data_1Y8J # _entry.id 1Y8J # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 1Y8J RCSB RCSB031250 WWPDB D_1000031250 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1R1J . unspecified PDB 1R1I . unspecified PDB 1R1H . unspecified PDB 1DMT . unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 1Y8J _pdbx_database_status.recvd_initial_deposition_date 2004-12-13 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry N _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Sahli, S.' 1 'Frank, B.' 2 'Schweizer, W.B.' 3 'Diederich, F.' 4 'Blum-Kaelin, D.' 5 'Aebi, J.D.' 6 'Bohm, H.J.' 7 'Oefner, C.' 8 'Dale, G.E.' 9 # _citation.id primary _citation.title ;Second-Generation Inhibitors for the Metalloprotease Neprilysin Based on Bicyclic Heteroaromatic Scaffolds: Synthesis, Biological Activity, and X-ray Crystal Structure Analysis ; _citation.journal_abbrev HELV.CHIM.ACTA _citation.journal_volume 88 _citation.page_first 731 _citation.page_last 750 _citation.year 2005 _citation.journal_id_ASTM HCACAV _citation.country SZ _citation.journal_id_ISSN 0018-019X _citation.journal_id_CSD 0010 _citation.book_publisher ? _citation.pdbx_database_id_PubMed -1 _citation.pdbx_database_id_DOI 10.1002/hlca.200590051 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Sahli, S.' 1 primary 'Frank, B.' 2 primary 'Schweizer, W.B.' 3 primary 'Diederich, F.' 4 primary 'Blum-Kaelin, D.' 5 primary 'Aebi, J.D.' 6 primary 'Bohm, H.J.' 7 primary 'Oefner, C.' 8 primary 'Dale, G.E.' 9 # _cell.entry_id 1Y8J _cell.length_a 107.355 _cell.length_b 107.356 _cell.length_c 112.466 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 6 _cell.pdbx_unique_axis ? # _symmetry.entry_id 1Y8J _symmetry.space_group_name_H-M 'P 32 2 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 154 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Neprilysin 79525.508 1 3.4.24.11 ? 'Extracellular domain (residues 54-179)' ? 2 non-polymer syn N-ACETYL-D-GLUCOSAMINE 221.208 3 ? ? ? ? 3 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 4 non-polymer syn 'ACETATE ION' 59.044 1 ? ? ? ? 5 non-polymer syn '2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM' 270.373 1 ? ? ? ? 6 water nat water 18.015 212 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Neutral endopeptidase, NEP, Enkephalinase, Common acute lymphocytic leukemia antigen, CALLA, Neutral endopeptidase 24.11, CD10' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;GICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQ KAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVN HVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRN DPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWR FIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQT LDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDE WISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASN FKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVW CGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW ; _entity_poly.pdbx_seq_one_letter_code_can ;GICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQ KAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVN HVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRN DPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWR FIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQT LDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDE WISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASN FKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVW CGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLY n 1 2 ILE n 1 3 CYS n 1 4 LYS n 1 5 SER n 1 6 SER n 1 7 ASP n 1 8 CYS n 1 9 ILE n 1 10 LYS n 1 11 SER n 1 12 ALA n 1 13 ALA n 1 14 ARG n 1 15 LEU n 1 16 ILE n 1 17 GLN n 1 18 ASN n 1 19 MET n 1 20 ASP n 1 21 ALA n 1 22 THR n 1 23 THR n 1 24 GLU n 1 25 PRO n 1 26 CYS n 1 27 THR n 1 28 ASP n 1 29 PHE n 1 30 PHE n 1 31 LYS n 1 32 TYR n 1 33 ALA n 1 34 CYS n 1 35 GLY n 1 36 GLY n 1 37 TRP n 1 38 LEU n 1 39 LYS n 1 40 ARG n 1 41 ASN n 1 42 VAL n 1 43 ILE n 1 44 PRO n 1 45 GLU n 1 46 THR n 1 47 SER n 1 48 SER n 1 49 ARG n 1 50 TYR n 1 51 GLY n 1 52 ASN n 1 53 PHE n 1 54 ASP n 1 55 ILE n 1 56 LEU n 1 57 ARG n 1 58 ASP n 1 59 GLU n 1 60 LEU n 1 61 GLU n 1 62 VAL n 1 63 VAL n 1 64 LEU n 1 65 LYS n 1 66 ASP n 1 67 VAL n 1 68 LEU n 1 69 GLN n 1 70 GLU n 1 71 PRO n 1 72 LYS n 1 73 THR n 1 74 GLU n 1 75 ASP n 1 76 ILE n 1 77 VAL n 1 78 ALA n 1 79 VAL n 1 80 GLN n 1 81 LYS n 1 82 ALA n 1 83 LYS n 1 84 ALA n 1 85 LEU n 1 86 TYR n 1 87 ARG n 1 88 SER n 1 89 CYS n 1 90 ILE n 1 91 ASN n 1 92 GLU n 1 93 SER n 1 94 ALA n 1 95 ILE n 1 96 ASP n 1 97 SER n 1 98 ARG n 1 99 GLY n 1 100 GLY n 1 101 GLU n 1 102 PRO n 1 103 LEU n 1 104 LEU n 1 105 LYS n 1 106 LEU n 1 107 LEU n 1 108 PRO n 1 109 ASP n 1 110 ILE n 1 111 TYR n 1 112 GLY n 1 113 TRP n 1 114 PRO n 1 115 VAL n 1 116 ALA n 1 117 THR n 1 118 GLU n 1 119 ASN n 1 120 TRP n 1 121 GLU n 1 122 GLN n 1 123 LYS n 1 124 TYR n 1 125 GLY n 1 126 ALA n 1 127 SER n 1 128 TRP n 1 129 THR n 1 130 ALA n 1 131 GLU n 1 132 LYS n 1 133 ALA n 1 134 ILE n 1 135 ALA n 1 136 GLN n 1 137 LEU n 1 138 ASN n 1 139 SER n 1 140 LYS n 1 141 TYR n 1 142 GLY n 1 143 LYS n 1 144 LYS n 1 145 VAL n 1 146 LEU n 1 147 ILE n 1 148 ASN n 1 149 LEU n 1 150 PHE n 1 151 VAL n 1 152 GLY n 1 153 THR n 1 154 ASP n 1 155 ASP n 1 156 LYS n 1 157 ASN n 1 158 SER n 1 159 VAL n 1 160 ASN n 1 161 HIS n 1 162 VAL n 1 163 ILE n 1 164 HIS n 1 165 ILE n 1 166 ASP n 1 167 GLN n 1 168 PRO n 1 169 ARG n 1 170 LEU n 1 171 GLY n 1 172 LEU n 1 173 PRO n 1 174 SER n 1 175 ARG n 1 176 ASP n 1 177 TYR n 1 178 TYR n 1 179 GLU n 1 180 CYS n 1 181 THR n 1 182 GLY n 1 183 ILE n 1 184 TYR n 1 185 LYS n 1 186 GLU n 1 187 ALA n 1 188 CYS n 1 189 THR n 1 190 ALA n 1 191 TYR n 1 192 VAL n 1 193 ASP n 1 194 PHE n 1 195 MET n 1 196 ILE n 1 197 SER n 1 198 VAL n 1 199 ALA n 1 200 ARG n 1 201 LEU n 1 202 ILE n 1 203 ARG n 1 204 GLN n 1 205 GLU n 1 206 GLU n 1 207 ARG n 1 208 LEU n 1 209 PRO n 1 210 ILE n 1 211 ASP n 1 212 GLU n 1 213 ASN n 1 214 GLN n 1 215 LEU n 1 216 ALA n 1 217 LEU n 1 218 GLU n 1 219 MET n 1 220 ASN n 1 221 LYS n 1 222 VAL n 1 223 MET n 1 224 GLU n 1 225 LEU n 1 226 GLU n 1 227 LYS n 1 228 GLU n 1 229 ILE n 1 230 ALA n 1 231 ASN n 1 232 ALA n 1 233 THR n 1 234 ALA n 1 235 LYS n 1 236 PRO n 1 237 GLU n 1 238 ASP n 1 239 ARG n 1 240 ASN n 1 241 ASP n 1 242 PRO n 1 243 MET n 1 244 LEU n 1 245 LEU n 1 246 TYR n 1 247 ASN n 1 248 LYS n 1 249 MET n 1 250 THR n 1 251 LEU n 1 252 ALA n 1 253 GLN n 1 254 ILE n 1 255 GLN n 1 256 ASN n 1 257 ASN n 1 258 PHE n 1 259 SER n 1 260 LEU n 1 261 GLU n 1 262 ILE n 1 263 ASN n 1 264 GLY n 1 265 LYS n 1 266 PRO n 1 267 PHE n 1 268 SER n 1 269 TRP n 1 270 LEU n 1 271 ASN n 1 272 PHE n 1 273 THR n 1 274 ASN n 1 275 GLU n 1 276 ILE n 1 277 MET n 1 278 SER n 1 279 THR n 1 280 VAL n 1 281 ASN n 1 282 ILE n 1 283 SER n 1 284 ILE n 1 285 THR n 1 286 ASN n 1 287 GLU n 1 288 GLU n 1 289 ASP n 1 290 VAL n 1 291 VAL n 1 292 VAL n 1 293 TYR n 1 294 ALA n 1 295 PRO n 1 296 GLU n 1 297 TYR n 1 298 LEU n 1 299 THR n 1 300 LYS n 1 301 LEU n 1 302 LYS n 1 303 PRO n 1 304 ILE n 1 305 LEU n 1 306 THR n 1 307 LYS n 1 308 TYR n 1 309 SER n 1 310 ALA n 1 311 ARG n 1 312 ASP n 1 313 LEU n 1 314 GLN n 1 315 ASN n 1 316 LEU n 1 317 MET n 1 318 SER n 1 319 TRP n 1 320 ARG n 1 321 PHE n 1 322 ILE n 1 323 MET n 1 324 ASP n 1 325 LEU n 1 326 VAL n 1 327 SER n 1 328 SER n 1 329 LEU n 1 330 SER n 1 331 ARG n 1 332 THR n 1 333 TYR n 1 334 LYS n 1 335 GLU n 1 336 SER n 1 337 ARG n 1 338 ASN n 1 339 ALA n 1 340 PHE n 1 341 ARG n 1 342 LYS n 1 343 ALA n 1 344 LEU n 1 345 TYR n 1 346 GLY n 1 347 THR n 1 348 THR n 1 349 SER n 1 350 GLU n 1 351 THR n 1 352 ALA n 1 353 THR n 1 354 TRP n 1 355 ARG n 1 356 ARG n 1 357 CYS n 1 358 ALA n 1 359 ASN n 1 360 TYR n 1 361 VAL n 1 362 ASN n 1 363 GLY n 1 364 ASN n 1 365 MET n 1 366 GLU n 1 367 ASN n 1 368 ALA n 1 369 VAL n 1 370 GLY n 1 371 ARG n 1 372 LEU n 1 373 TYR n 1 374 VAL n 1 375 GLU n 1 376 ALA n 1 377 ALA n 1 378 PHE n 1 379 ALA n 1 380 GLY n 1 381 GLU n 1 382 SER n 1 383 LYS n 1 384 HIS n 1 385 VAL n 1 386 VAL n 1 387 GLU n 1 388 ASP n 1 389 LEU n 1 390 ILE n 1 391 ALA n 1 392 GLN n 1 393 ILE n 1 394 ARG n 1 395 GLU n 1 396 VAL n 1 397 PHE n 1 398 ILE n 1 399 GLN n 1 400 THR n 1 401 LEU n 1 402 ASP n 1 403 ASP n 1 404 LEU n 1 405 THR n 1 406 TRP n 1 407 MET n 1 408 ASP n 1 409 ALA n 1 410 GLU n 1 411 THR n 1 412 LYS n 1 413 LYS n 1 414 ARG n 1 415 ALA n 1 416 GLU n 1 417 GLU n 1 418 LYS n 1 419 ALA n 1 420 LEU n 1 421 ALA n 1 422 ILE n 1 423 LYS n 1 424 GLU n 1 425 ARG n 1 426 ILE n 1 427 GLY n 1 428 TYR n 1 429 PRO n 1 430 ASP n 1 431 ASP n 1 432 ILE n 1 433 VAL n 1 434 SER n 1 435 ASN n 1 436 ASP n 1 437 ASN n 1 438 LYS n 1 439 LEU n 1 440 ASN n 1 441 ASN n 1 442 GLU n 1 443 TYR n 1 444 LEU n 1 445 GLU n 1 446 LEU n 1 447 ASN n 1 448 TYR n 1 449 LYS n 1 450 GLU n 1 451 ASP n 1 452 GLU n 1 453 TYR n 1 454 PHE n 1 455 GLU n 1 456 ASN n 1 457 ILE n 1 458 ILE n 1 459 GLN n 1 460 ASN n 1 461 LEU n 1 462 LYS n 1 463 PHE n 1 464 SER n 1 465 GLN n 1 466 SER n 1 467 LYS n 1 468 GLN n 1 469 LEU n 1 470 LYS n 1 471 LYS n 1 472 LEU n 1 473 ARG n 1 474 GLU n 1 475 LYS n 1 476 VAL n 1 477 ASP n 1 478 LYS n 1 479 ASP n 1 480 GLU n 1 481 TRP n 1 482 ILE n 1 483 SER n 1 484 GLY n 1 485 ALA n 1 486 ALA n 1 487 VAL n 1 488 VAL n 1 489 ASN n 1 490 ALA n 1 491 PHE n 1 492 TYR n 1 493 SER n 1 494 SER n 1 495 GLY n 1 496 ARG n 1 497 ASN n 1 498 GLN n 1 499 ILE n 1 500 VAL n 1 501 PHE n 1 502 PRO n 1 503 ALA n 1 504 GLY n 1 505 ILE n 1 506 LEU n 1 507 GLN n 1 508 PRO n 1 509 PRO n 1 510 PHE n 1 511 PHE n 1 512 SER n 1 513 ALA n 1 514 GLN n 1 515 GLN n 1 516 SER n 1 517 ASN n 1 518 SER n 1 519 LEU n 1 520 ASN n 1 521 TYR n 1 522 GLY n 1 523 GLY n 1 524 ILE n 1 525 GLY n 1 526 MET n 1 527 VAL n 1 528 ILE n 1 529 GLY n 1 530 HIS n 1 531 GLU n 1 532 ILE n 1 533 THR n 1 534 HIS n 1 535 GLY n 1 536 PHE n 1 537 ASP n 1 538 ASP n 1 539 ASN n 1 540 GLY n 1 541 ARG n 1 542 ASN n 1 543 PHE n 1 544 ASN n 1 545 LYS n 1 546 ASP n 1 547 GLY n 1 548 ASP n 1 549 LEU n 1 550 VAL n 1 551 ASP n 1 552 TRP n 1 553 TRP n 1 554 THR n 1 555 GLN n 1 556 GLN n 1 557 SER n 1 558 ALA n 1 559 SER n 1 560 ASN n 1 561 PHE n 1 562 LYS n 1 563 GLU n 1 564 GLN n 1 565 SER n 1 566 GLN n 1 567 CYS n 1 568 MET n 1 569 VAL n 1 570 TYR n 1 571 GLN n 1 572 TYR n 1 573 GLY n 1 574 ASN n 1 575 PHE n 1 576 SER n 1 577 TRP n 1 578 ASP n 1 579 LEU n 1 580 ALA n 1 581 GLY n 1 582 GLY n 1 583 GLN n 1 584 HIS n 1 585 LEU n 1 586 ASN n 1 587 GLY n 1 588 ILE n 1 589 ASN n 1 590 THR n 1 591 LEU n 1 592 GLY n 1 593 GLU n 1 594 ASN n 1 595 ILE n 1 596 ALA n 1 597 ASP n 1 598 ASN n 1 599 GLY n 1 600 GLY n 1 601 LEU n 1 602 GLY n 1 603 GLN n 1 604 ALA n 1 605 TYR n 1 606 ARG n 1 607 ALA n 1 608 TYR n 1 609 GLN n 1 610 ASN n 1 611 TYR n 1 612 ILE n 1 613 LYS n 1 614 LYS n 1 615 ASN n 1 616 GLY n 1 617 GLU n 1 618 GLU n 1 619 LYS n 1 620 LEU n 1 621 LEU n 1 622 PRO n 1 623 GLY n 1 624 LEU n 1 625 ASP n 1 626 LEU n 1 627 ASN n 1 628 HIS n 1 629 LYS n 1 630 GLN n 1 631 LEU n 1 632 PHE n 1 633 PHE n 1 634 LEU n 1 635 ASN n 1 636 PHE n 1 637 ALA n 1 638 GLN n 1 639 VAL n 1 640 TRP n 1 641 CYS n 1 642 GLY n 1 643 THR n 1 644 TYR n 1 645 ARG n 1 646 PRO n 1 647 GLU n 1 648 TYR n 1 649 ALA n 1 650 VAL n 1 651 ASN n 1 652 SER n 1 653 ILE n 1 654 LYS n 1 655 THR n 1 656 ASP n 1 657 VAL n 1 658 HIS n 1 659 SER n 1 660 PRO n 1 661 GLY n 1 662 ASN n 1 663 PHE n 1 664 ARG n 1 665 ILE n 1 666 ILE n 1 667 GLY n 1 668 THR n 1 669 LEU n 1 670 GLN n 1 671 ASN n 1 672 SER n 1 673 ALA n 1 674 GLU n 1 675 PHE n 1 676 SER n 1 677 GLU n 1 678 ALA n 1 679 PHE n 1 680 HIS n 1 681 CYS n 1 682 ARG n 1 683 LYS n 1 684 ASN n 1 685 SER n 1 686 TYR n 1 687 MET n 1 688 ASN n 1 689 PRO n 1 690 GLU n 1 691 LYS n 1 692 LYS n 1 693 CYS n 1 694 ARG n 1 695 VAL n 1 696 TRP n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus Homo _entity_src_gen.pdbx_gene_src_gene 'MME, EPN' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ;baker's yeast ; _entity_src_gen.pdbx_host_org_scientific_name 'Saccharomyces cerevisiae' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 4932 _entity_src_gen.host_org_genus Saccharomyces _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code NEP_HUMAN _struct_ref.pdbx_db_accession P08473 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;GICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQ KAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVN HVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRN DPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWR FIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQT LDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDE WISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASN FKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVW CGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW ; _struct_ref.pdbx_align_begin 54 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 1Y8J _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 696 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession P08473 _struct_ref_seq.db_align_beg 54 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 749 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 54 _struct_ref_seq.pdbx_auth_seq_align_end 749 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ACT non-polymer . 'ACETATE ION' ? 'C2 H3 O2 -1' 59.044 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 STS non-polymer . '2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM' ? 'C15 H16 N3 S 1' 270.373 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 1Y8J _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.35 _exptl_crystal.density_percent_sol 47.72 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp ? _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pdbx_details 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector 'IMAGE PLATE' _diffrn_detector.type MARRESEARCH _diffrn_detector.pdbx_collection_date 2003-08-13 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'osmic mirror' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength . _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source 'ROTATING ANODE' _diffrn_source.type 'ENRAF-NONIUS FR591' _diffrn_source.pdbx_synchrotron_site ? _diffrn_source.pdbx_synchrotron_beamline ? _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list ? # _reflns.entry_id 1Y8J _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.d_resolution_high 2.25 _reflns.d_resolution_low 20.0 _reflns.number_all ? _reflns.number_obs 34323 _reflns.percent_possible_obs 95.4 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy ? _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 2.25 _reflns_shell.d_res_low 2.39 _reflns_shell.percent_possible_all 84.9 _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 1Y8J _refine.ls_number_reflns_obs 32573 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 20.00 _refine.ls_d_res_high 2.25 _refine.ls_percent_reflns_obs 95.46 _refine.ls_R_factor_obs 0.22984 _refine.ls_R_factor_all 0.22639 _refine.ls_R_factor_R_work 0.22639 _refine.ls_R_factor_R_free 0.29637 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.0 _refine.ls_number_reflns_R_free 1732 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.917 _refine.correlation_coeff_Fo_to_Fc_free 0.866 _refine.B_iso_mean 27.668 _refine.aniso_B[1][1] 0.32 _refine.aniso_B[2][2] 0.32 _refine.aniso_B[3][3] -0.48 _refine.aniso_B[1][2] 0.16 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'BABINET MODEL WITH MASK' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.40 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model 'PDB entry 1DMT' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.423 _refine.pdbx_overall_ESU_R_Free 0.293 _refine.overall_SU_ML 0.310 _refine.overall_SU_B 12.474 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 5595 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 66 _refine_hist.number_atoms_solvent 212 _refine_hist.number_atoms_total 5873 _refine_hist.d_res_high 2.25 _refine_hist.d_res_low 20.00 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.007 0.021 ? 5788 'X-RAY DIFFRACTION' ? r_bond_other_d 0.001 0.020 ? 5066 'X-RAY DIFFRACTION' ? r_angle_refined_deg 0.889 1.954 ? 7834 'X-RAY DIFFRACTION' ? r_angle_other_deg 0.552 3.000 ? 11826 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 9.083 3.000 ? 695 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 24.031 15.000 ? 1037 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_chiral_restr 0.047 0.200 ? 840 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.003 0.020 ? 6441 'X-RAY DIFFRACTION' ? r_gen_planes_other 0.002 0.020 ? 1164 'X-RAY DIFFRACTION' ? r_nbd_refined 0.299 0.300 ? 1712 'X-RAY DIFFRACTION' ? r_nbd_other 0.278 0.300 ? 5669 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other 0.749 0.500 ? 3 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 0.208 0.500 ? 327 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other 0.182 0.500 ? 18 'X-RAY DIFFRACTION' ? r_metal_ion_refined 0.161 0.500 ? 1 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 0.664 0.300 ? 39 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other 0.437 0.300 ? 36 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 0.472 0.500 ? 5 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 1.899 2.000 ? 3464 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 2.933 3.000 ? 5574 'X-RAY DIFFRACTION' ? r_scbond_it 1.925 2.000 ? 2324 'X-RAY DIFFRACTION' ? r_scangle_it 2.951 3.000 ? 2260 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 10 _refine_ls_shell.d_res_high 2.250 _refine_ls_shell.d_res_low 2.370 _refine_ls_shell.number_reflns_R_work 4074 _refine_ls_shell.R_factor_R_work 0.271 _refine_ls_shell.percent_reflns_obs ? _refine_ls_shell.R_factor_R_free 0.34 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 206 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.number_reflns_all ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.R_factor_all ? # _struct.entry_id 1Y8J _struct.title 'Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor' _struct.pdbx_descriptor 'Neprilysin (E.C.3.4.24.11)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 1Y8J _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'LT1_6, HYDROLASE' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 2 ? E N N 3 ? F N N 4 ? G N N 5 ? H N N 6 ? # _struct_biol.id 1 _struct_biol.pdbx_parent_biol_id ? _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 SER A 5 ? MET A 19 ? SER A 58 MET A 72 1 ? 15 HELX_P HELX_P2 2 ASP A 28 ? ASN A 41 ? ASP A 81 ASN A 94 1 ? 14 HELX_P HELX_P3 3 ASN A 52 ? GLN A 69 ? ASN A 105 GLN A 122 1 ? 18 HELX_P HELX_P4 4 ILE A 76 ? ASN A 91 ? ILE A 129 ASN A 144 1 ? 16 HELX_P HELX_P5 5 ASN A 91 ? ARG A 98 ? ASN A 144 ARG A 151 1 ? 8 HELX_P HELX_P6 6 GLY A 100 ? LYS A 105 ? GLY A 153 LYS A 158 1 ? 6 HELX_P HELX_P7 7 LEU A 106 ? TYR A 111 ? LEU A 159 TYR A 164 5 ? 6 HELX_P HELX_P8 8 TRP A 113 ? THR A 117 ? TRP A 166 THR A 170 5 ? 5 HELX_P HELX_P9 9 ASN A 119 ? TYR A 124 ? ASN A 172 TYR A 177 1 ? 6 HELX_P HELX_P10 10 THR A 129 ? TYR A 141 ? THR A 182 TYR A 194 1 ? 13 HELX_P HELX_P11 11 SER A 174 ? CYS A 180 ? SER A 227 CYS A 233 5 ? 7 HELX_P HELX_P12 12 THR A 181 ? ILE A 183 ? THR A 234 ILE A 236 5 ? 3 HELX_P HELX_P13 13 TYR A 184 ? GLU A 206 ? TYR A 237 GLU A 259 1 ? 23 HELX_P HELX_P14 14 ASP A 211 ? THR A 233 ? ASP A 264 THR A 286 1 ? 23 HELX_P HELX_P15 15 LYS A 235 ? ARG A 239 ? LYS A 288 ARG A 292 5 ? 5 HELX_P HELX_P16 16 ASP A 241 ? TYR A 246 ? ASP A 294 TYR A 299 1 ? 6 HELX_P HELX_P17 17 LEU A 251 ? PHE A 258 ? LEU A 304 PHE A 311 1 ? 8 HELX_P HELX_P18 18 SER A 268 ? SER A 278 ? SER A 321 SER A 331 1 ? 11 HELX_P HELX_P19 19 THR A 279 ? ASN A 281 ? THR A 332 ASN A 334 5 ? 3 HELX_P HELX_P20 20 ALA A 294 ? THR A 306 ? ALA A 347 THR A 359 1 ? 13 HELX_P HELX_P21 21 SER A 309 ? MET A 323 ? SER A 362 MET A 376 1 ? 15 HELX_P HELX_P22 22 ASP A 324 ? LEU A 329 ? ASP A 377 LEU A 382 5 ? 6 HELX_P HELX_P23 23 SER A 330 ? SER A 336 ? SER A 383 SER A 389 1 ? 7 HELX_P HELX_P24 24 ARG A 337 ? GLY A 346 ? ARG A 390 GLY A 399 1 ? 10 HELX_P HELX_P25 25 ALA A 352 ? MET A 365 ? ALA A 405 MET A 418 1 ? 14 HELX_P HELX_P26 26 MET A 365 ? PHE A 378 ? MET A 418 PHE A 431 1 ? 14 HELX_P HELX_P27 27 GLU A 381 ? LEU A 401 ? GLU A 434 LEU A 454 1 ? 21 HELX_P HELX_P28 28 ASP A 408 ? ALA A 421 ? ASP A 461 ALA A 474 1 ? 14 HELX_P HELX_P29 29 ASP A 430 ? ASN A 435 ? ASP A 483 ASN A 488 1 ? 6 HELX_P HELX_P30 30 ASN A 435 ? TYR A 443 ? ASN A 488 TYR A 496 1 ? 9 HELX_P HELX_P31 31 GLU A 452 ? LYS A 470 ? GLU A 505 LYS A 523 1 ? 19 HELX_P HELX_P32 32 GLY A 504 ? LEU A 506 ? GLY A 557 LEU A 559 5 ? 3 HELX_P HELX_P33 33 SER A 516 ? HIS A 534 ? SER A 569 HIS A 587 1 ? 19 HELX_P HELX_P34 34 GLY A 535 ? ASP A 537 ? GLY A 588 ASP A 590 5 ? 3 HELX_P HELX_P35 35 ASN A 539 ? PHE A 543 ? ASN A 592 PHE A 596 5 ? 5 HELX_P HELX_P36 36 THR A 554 ? ASN A 574 ? THR A 607 ASN A 627 1 ? 21 HELX_P HELX_P37 37 TRP A 577 ? GLY A 581 ? TRP A 630 GLY A 634 5 ? 5 HELX_P HELX_P38 38 THR A 590 ? GLY A 616 ? THR A 643 GLY A 669 1 ? 27 HELX_P HELX_P39 39 ASN A 627 ? VAL A 639 ? ASN A 680 VAL A 692 1 ? 13 HELX_P HELX_P40 40 ARG A 645 ? ASP A 656 ? ARG A 698 ASP A 709 1 ? 12 HELX_P HELX_P41 41 PRO A 660 ? ASN A 671 ? PRO A 713 ASN A 724 1 ? 12 HELX_P HELX_P42 42 SER A 672 ? PHE A 679 ? SER A 725 PHE A 732 1 ? 8 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 3 SG ? ? ? 1_555 A CYS 8 SG ? ? A CYS 56 A CYS 61 1_555 ? ? ? ? ? ? ? 2.036 ? disulf2 disulf ? ? A CYS 26 SG ? ? ? 1_555 A CYS 681 SG ? ? A CYS 79 A CYS 734 1_555 ? ? ? ? ? ? ? 2.025 ? disulf3 disulf ? ? A CYS 34 SG ? ? ? 1_555 A CYS 641 SG ? ? A CYS 87 A CYS 694 1_555 ? ? ? ? ? ? ? 2.034 ? disulf4 disulf ? ? A CYS 89 SG ? ? ? 1_555 A CYS 357 SG ? ? A CYS 142 A CYS 410 1_555 ? ? ? ? ? ? ? 2.023 ? disulf5 disulf ? ? A CYS 180 SG ? ? ? 1_555 A CYS 188 SG ? ? A CYS 233 A CYS 241 1_555 ? ? ? ? ? ? ? 2.038 ? disulf6 disulf ? ? A CYS 567 SG ? ? ? 1_555 A CYS 693 SG ? ? A CYS 620 A CYS 746 1_555 ? ? ? ? ? ? ? 2.042 ? covale1 covale ? ? A ASN 91 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 144 A NAG 752 1_555 ? ? ? ? ? ? ? 1.441 ? covale2 covale ? ? A ASN 271 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 324 A NAG 753 1_555 ? ? ? ? ? ? ? 1.438 ? covale3 covale ? ? A ASN 574 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 627 A NAG 754 1_555 ? ? ? ? ? ? ? 1.440 ? metalc1 metalc ? ? E ZN . ZN ? ? ? 1_555 A HIS 534 NE2 ? ? A ZN 800 A HIS 587 1_555 ? ? ? ? ? ? ? 2.048 ? metalc2 metalc ? ? E ZN . ZN ? ? ? 1_555 A HIS 530 NE2 ? ? A ZN 800 A HIS 583 1_555 ? ? ? ? ? ? ? 1.900 ? metalc3 metalc ? ? E ZN . ZN ? ? ? 1_555 A GLU 593 OE1 ? ? A ZN 800 A GLU 646 1_555 ? ? ? ? ? ? ? 2.082 ? metalc4 metalc ? ? E ZN . ZN ? ? ? 1_555 G STS . S10 ? ? A ZN 800 A STS 900 1_555 ? ? ? ? ? ? ? 2.204 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 LYS 265 A . ? LYS 318 A PRO 266 A ? PRO 319 A 1 -3.79 2 PRO 508 A . ? PRO 561 A PRO 509 A ? PRO 562 A 1 5.40 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 4 ? C ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? parallel B 3 4 ? anti-parallel C 1 2 ? parallel C 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 ARG A 49 ? GLY A 51 ? ARG A 102 GLY A 104 A 2 GLY A 642 ? TYR A 644 ? GLY A 695 TYR A 697 B 1 ASN A 148 ? ASP A 154 ? ASN A 201 ASP A 207 B 2 ASN A 157 ? ASP A 166 ? ASN A 210 ASP A 219 B 3 ASP A 289 ? VAL A 292 ? ASP A 342 VAL A 345 B 4 ASN A 247 ? THR A 250 ? ASN A 300 THR A 303 C 1 LYS A 423 ? GLY A 427 ? LYS A 476 GLY A 480 C 2 GLN A 498 ? PRO A 502 ? GLN A 551 PRO A 555 C 3 PHE A 491 ? SER A 493 ? PHE A 544 SER A 546 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N TYR A 50 ? N TYR A 103 O THR A 643 ? O THR A 696 B 1 2 N GLY A 152 ? N GLY A 205 O VAL A 162 ? O VAL A 215 B 2 3 N ILE A 163 ? N ILE A 216 O VAL A 291 ? O VAL A 344 B 3 4 O VAL A 290 ? O VAL A 343 N MET A 249 ? N MET A 302 C 1 2 N GLY A 427 ? N GLY A 480 O PHE A 501 ? O PHE A 554 C 2 3 O GLN A 498 ? O GLN A 551 N SER A 493 ? N SER A 546 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 752' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 753' AC3 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 754' AC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ZN A 800' AC5 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE ACT A 801' AC6 Software ? ? ? ? 11 'BINDING SITE FOR RESIDUE STS A 900' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 2 ASN A 91 ? ASN A 144 . ? 1_555 ? 2 AC1 2 ALA A 94 ? ALA A 147 . ? 1_555 ? 3 AC2 5 ASN A 271 ? ASN A 324 . ? 1_555 ? 4 AC2 5 ASN A 274 ? ASN A 327 . ? 1_555 ? 5 AC2 5 GLU A 275 ? GLU A 328 . ? 1_555 ? 6 AC2 5 HOH H . ? HOH A 1046 . ? 1_555 ? 7 AC2 5 HOH H . ? HOH A 1047 . ? 1_555 ? 8 AC3 3 TYR A 570 ? TYR A 623 . ? 1_555 ? 9 AC3 3 GLY A 573 ? GLY A 626 . ? 1_555 ? 10 AC3 3 ASN A 574 ? ASN A 627 . ? 1_555 ? 11 AC4 4 HIS A 530 ? HIS A 583 . ? 1_555 ? 12 AC4 4 HIS A 534 ? HIS A 587 . ? 1_555 ? 13 AC4 4 GLU A 593 ? GLU A 646 . ? 1_555 ? 14 AC4 4 STS G . ? STS A 900 . ? 1_555 ? 15 AC5 7 VAL A 145 ? VAL A 198 . ? 1_555 ? 16 AC5 7 LEU A 146 ? LEU A 199 . ? 1_555 ? 17 AC5 7 ARG A 169 ? ARG A 222 . ? 1_555 ? 18 AC5 7 LEU A 170 ? LEU A 223 . ? 1_555 ? 19 AC5 7 GLU A 226 ? GLU A 279 . ? 1_555 ? 20 AC5 7 ILE A 229 ? ILE A 282 . ? 1_555 ? 21 AC5 7 ARG A 320 ? ARG A 373 . ? 1_555 ? 22 AC6 11 ARG A 57 ? ARG A 110 . ? 1_555 ? 23 AC6 11 ASN A 489 ? ASN A 542 . ? 1_555 ? 24 AC6 11 ALA A 490 ? ALA A 543 . ? 1_555 ? 25 AC6 11 MET A 526 ? MET A 579 . ? 1_555 ? 26 AC6 11 HIS A 530 ? HIS A 583 . ? 1_555 ? 27 AC6 11 GLU A 531 ? GLU A 584 . ? 1_555 ? 28 AC6 11 GLU A 593 ? GLU A 646 . ? 1_555 ? 29 AC6 11 TRP A 640 ? TRP A 693 . ? 1_555 ? 30 AC6 11 HIS A 658 ? HIS A 711 . ? 1_555 ? 31 AC6 11 ARG A 664 ? ARG A 717 . ? 1_555 ? 32 AC6 11 ZN E . ? ZN A 800 . ? 1_555 ? # _database_PDB_matrix.entry_id 1Y8J _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 1Y8J _atom_sites.fract_transf_matrix[1][1] 0.009315 _atom_sites.fract_transf_matrix[1][2] 0.005378 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.010756 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.008892 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLY A 1 1 ? -39.161 75.251 32.131 1.00 38.68 ? 54 GLY A N 1 ATOM 2 C CA . GLY A 1 1 ? -39.889 74.226 31.317 1.00 41.39 ? 54 GLY A CA 1 ATOM 3 C C . GLY A 1 1 ? -39.129 72.912 31.239 1.00 42.18 ? 54 GLY A C 1 ATOM 4 O O . GLY A 1 1 ? -38.812 72.433 30.150 1.00 42.93 ? 54 GLY A O 1 ATOM 5 N N . ILE A 1 2 ? -38.812 72.354 32.404 1.00 41.78 ? 55 ILE A N 1 ATOM 6 C CA . ILE A 1 2 ? -38.382 70.962 32.541 1.00 42.59 ? 55 ILE A CA 1 ATOM 7 C C . ILE A 1 2 ? -39.512 69.948 32.373 1.00 40.72 ? 55 ILE A C 1 ATOM 8 O O . ILE A 1 2 ? -40.511 69.999 33.093 1.00 42.82 ? 55 ILE A O 1 ATOM 9 C CB . ILE A 1 2 ? -37.756 70.788 33.928 1.00 43.91 ? 55 ILE A CB 1 ATOM 10 C CG1 . ILE A 1 2 ? -36.737 71.901 34.172 1.00 44.70 ? 55 ILE A CG1 1 ATOM 11 C CG2 . ILE A 1 2 ? -37.110 69.429 34.061 1.00 44.99 ? 55 ILE A CG2 1 ATOM 12 C CD1 . ILE A 1 2 ? -35.955 72.261 32.945 1.00 45.76 ? 55 ILE A CD1 1 ATOM 13 N N . CYS A 1 3 ? -39.337 69.008 31.444 1.00 37.97 ? 56 CYS A N 1 ATOM 14 C CA . CYS A 1 3 ? -40.053 67.721 31.485 1.00 36.64 ? 56 CYS A CA 1 ATOM 15 C C . CYS A 1 3 ? -39.916 66.997 32.830 1.00 37.82 ? 56 CYS A C 1 ATOM 16 O O . CYS A 1 3 ? -38.814 66.838 33.355 1.00 35.59 ? 56 CYS A O 1 ATOM 17 C CB . CYS A 1 3 ? -39.560 66.799 30.363 1.00 35.81 ? 56 CYS A CB 1 ATOM 18 S SG . CYS A 1 3 ? -40.483 65.253 30.239 1.00 33.63 ? 56 CYS A SG 1 ATOM 19 N N . LYS A 1 4 ? -41.039 66.552 33.390 1.00 39.91 ? 57 LYS A N 1 ATOM 20 C CA . LYS A 1 4 ? -41.007 65.811 34.652 1.00 39.53 ? 57 LYS A CA 1 ATOM 21 C C . LYS A 1 4 ? -41.831 64.532 34.583 1.00 36.62 ? 57 LYS A C 1 ATOM 22 O O . LYS A 1 4 ? -42.405 64.104 35.577 1.00 36.55 ? 57 LYS A O 1 ATOM 23 C CB . LYS A 1 4 ? -41.507 66.683 35.802 1.00 40.85 ? 57 LYS A CB 1 ATOM 24 C CG . LYS A 1 4 ? -42.638 67.613 35.413 1.00 44.31 ? 57 LYS A CG 1 ATOM 25 C CD . LYS A 1 4 ? -42.196 69.070 35.470 1.00 47.15 ? 57 LYS A CD 1 ATOM 26 C CE . LYS A 1 4 ? -41.298 69.324 36.670 1.00 47.58 ? 57 LYS A CE 1 ATOM 27 N NZ . LYS A 1 4 ? -42.017 70.096 37.718 1.00 50.05 ? 57 LYS A NZ 1 ATOM 28 N N . SER A 1 5 ? -41.888 63.921 33.409 1.00 37.71 ? 58 SER A N 1 ATOM 29 C CA . SER A 1 5 ? -42.534 62.619 33.258 1.00 37.56 ? 58 SER A CA 1 ATOM 30 C C . SER A 1 5 ? -41.736 61.480 33.907 1.00 35.34 ? 58 SER A C 1 ATOM 31 O O . SER A 1 5 ? -40.531 61.582 34.136 1.00 36.64 ? 58 SER A O 1 ATOM 32 C CB . SER A 1 5 ? -42.740 62.305 31.777 1.00 38.65 ? 58 SER A CB 1 ATOM 33 O OG . SER A 1 5 ? -41.494 62.251 31.096 1.00 40.29 ? 58 SER A OG 1 ATOM 34 N N . SER A 1 6 ? -42.427 60.388 34.187 1.00 34.93 ? 59 SER A N 1 ATOM 35 C CA . SER A 1 6 ? -41.790 59.144 34.580 1.00 34.02 ? 59 SER A CA 1 ATOM 36 C C . SER A 1 6 ? -40.629 58.828 33.656 1.00 34.45 ? 59 SER A C 1 ATOM 37 O O . SER A 1 6 ? -39.502 58.586 34.091 1.00 31.46 ? 59 SER A O 1 ATOM 38 C CB . SER A 1 6 ? -42.809 58.009 34.525 1.00 32.92 ? 59 SER A CB 1 ATOM 39 O OG . SER A 1 6 ? -43.078 57.517 35.820 1.00 33.69 ? 59 SER A OG 1 ATOM 40 N N . ASP A 1 7 ? -40.919 58.813 32.366 1.00 35.62 ? 60 ASP A N 1 ATOM 41 C CA . ASP A 1 7 ? -39.938 58.395 31.384 1.00 35.12 ? 60 ASP A CA 1 ATOM 42 C C . ASP A 1 7 ? -38.804 59.415 31.308 1.00 32.31 ? 60 ASP A C 1 ATOM 43 O O . ASP A 1 7 ? -37.656 59.065 31.069 1.00 28.73 ? 60 ASP A O 1 ATOM 44 C CB . ASP A 1 7 ? -40.625 58.219 30.037 1.00 37.09 ? 60 ASP A CB 1 ATOM 45 C CG . ASP A 1 7 ? -41.797 57.253 30.116 1.00 39.43 ? 60 ASP A CG 1 ATOM 46 O OD1 . ASP A 1 7 ? -41.569 56.059 30.415 1.00 38.77 ? 60 ASP A OD1 1 ATOM 47 O OD2 . ASP A 1 7 ? -42.980 57.601 29.915 1.00 41.87 ? 60 ASP A OD2 1 ATOM 48 N N . CYS A 1 8 ? -39.128 60.677 31.547 1.00 31.95 ? 61 CYS A N 1 ATOM 49 C CA . CYS A 1 8 ? -38.100 61.705 31.621 1.00 32.84 ? 61 CYS A CA 1 ATOM 50 C C . CYS A 1 8 ? -37.222 61.521 32.846 1.00 28.12 ? 61 CYS A C 1 ATOM 51 O O . CYS A 1 8 ? -36.016 61.713 32.776 1.00 28.78 ? 61 CYS A O 1 ATOM 52 C CB . CYS A 1 8 ? -38.727 63.097 31.631 1.00 34.09 ? 61 CYS A CB 1 ATOM 53 S SG . CYS A 1 8 ? -39.250 63.651 29.993 1.00 38.15 ? 61 CYS A SG 1 ATOM 54 N N . ILE A 1 9 ? -37.824 61.149 33.967 1.00 25.71 ? 62 ILE A N 1 ATOM 55 C CA . ILE A 1 9 ? -37.051 60.908 35.168 1.00 25.62 ? 62 ILE A CA 1 ATOM 56 C C . ILE A 1 9 ? -36.085 59.757 34.963 1.00 22.62 ? 62 ILE A C 1 ATOM 57 O O . ILE A 1 9 ? -34.939 59.827 35.397 1.00 21.11 ? 62 ILE A O 1 ATOM 58 C CB . ILE A 1 9 ? -37.961 60.628 36.372 1.00 27.97 ? 62 ILE A CB 1 ATOM 59 C CG1 . ILE A 1 9 ? -38.315 61.932 37.083 1.00 29.16 ? 62 ILE A CG1 1 ATOM 60 C CG2 . ILE A 1 9 ? -37.268 59.712 37.354 1.00 28.51 ? 62 ILE A CG2 1 ATOM 61 C CD1 . ILE A 1 9 ? -38.803 63.003 36.157 1.00 28.78 ? 62 ILE A CD1 1 ATOM 62 N N . LYS A 1 10 ? -36.533 58.705 34.286 1.00 21.73 ? 63 LYS A N 1 ATOM 63 C CA . LYS A 1 10 ? -35.681 57.541 34.065 1.00 22.81 ? 63 LYS A CA 1 ATOM 64 C C . LYS A 1 10 ? -34.499 57.926 33.190 1.00 22.75 ? 63 LYS A C 1 ATOM 65 O O . LYS A 1 10 ? -33.346 57.660 33.514 1.00 16.60 ? 63 LYS A O 1 ATOM 66 C CB . LYS A 1 10 ? -36.467 56.402 33.411 1.00 24.07 ? 63 LYS A CB 1 ATOM 67 C CG . LYS A 1 10 ? -37.238 55.540 34.395 1.00 26.41 ? 63 LYS A CG 1 ATOM 68 C CD . LYS A 1 10 ? -38.533 55.030 33.780 1.00 28.17 ? 63 LYS A CD 1 ATOM 69 C CE . LYS A 1 10 ? -38.772 53.576 34.120 1.00 29.69 ? 63 LYS A CE 1 ATOM 70 N NZ . LYS A 1 10 ? -39.861 52.997 33.294 1.00 29.01 ? 63 LYS A NZ 1 ATOM 71 N N . SER A 1 11 ? -34.816 58.552 32.068 1.00 27.23 ? 64 SER A N 1 ATOM 72 C CA . SER A 1 11 ? -33.820 59.018 31.126 1.00 27.92 ? 64 SER A CA 1 ATOM 73 C C . SER A 1 11 ? -32.736 59.828 31.821 1.00 25.38 ? 64 SER A C 1 ATOM 74 O O . SER A 1 11 ? -31.555 59.484 31.759 1.00 24.54 ? 64 SER A O 1 ATOM 75 C CB . SER A 1 11 ? -34.500 59.880 30.070 1.00 28.18 ? 64 SER A CB 1 ATOM 76 O OG . SER A 1 11 ? -34.616 59.154 28.880 1.00 31.91 ? 64 SER A OG 1 ATOM 77 N N . ALA A 1 12 ? -33.150 60.898 32.489 1.00 22.22 ? 65 ALA A N 1 ATOM 78 C CA . ALA A 1 12 ? -32.205 61.823 33.108 1.00 22.51 ? 65 ALA A CA 1 ATOM 79 C C . ALA A 1 12 ? -31.291 61.104 34.089 1.00 21.27 ? 65 ALA A C 1 ATOM 80 O O . ALA A 1 12 ? -30.081 61.330 34.099 1.00 21.48 ? 65 ALA A O 1 ATOM 81 C CB . ALA A 1 12 ? -32.950 62.933 33.801 1.00 22.43 ? 65 ALA A CB 1 ATOM 82 N N . ALA A 1 13 ? -31.873 60.222 34.896 1.00 20.64 ? 66 ALA A N 1 ATOM 83 C CA . ALA A 1 13 ? -31.135 59.539 35.948 1.00 19.20 ? 66 ALA A CA 1 ATOM 84 C C . ALA A 1 13 ? -30.055 58.664 35.351 1.00 21.75 ? 66 ALA A C 1 ATOM 85 O O . ALA A 1 13 ? -28.938 58.604 35.870 1.00 22.62 ? 66 ALA A O 1 ATOM 86 C CB . ALA A 1 13 ? -32.063 58.703 36.796 1.00 17.72 ? 66 ALA A CB 1 ATOM 87 N N . ARG A 1 14 ? -30.387 57.978 34.261 1.00 21.62 ? 67 ARG A N 1 ATOM 88 C CA . ARG A 1 14 ? -29.401 57.179 33.549 1.00 22.46 ? 67 ARG A CA 1 ATOM 89 C C . ARG A 1 14 ? -28.277 58.046 32.977 1.00 21.73 ? 67 ARG A C 1 ATOM 90 O O . ARG A 1 14 ? -27.103 57.716 33.111 1.00 26.06 ? 67 ARG A O 1 ATOM 91 C CB . ARG A 1 14 ? -30.065 56.386 32.425 1.00 23.17 ? 67 ARG A CB 1 ATOM 92 C CG . ARG A 1 14 ? -29.125 55.434 31.730 1.00 22.38 ? 67 ARG A CG 1 ATOM 93 C CD . ARG A 1 14 ? -28.457 56.033 30.517 1.00 22.18 ? 67 ARG A CD 1 ATOM 94 N NE . ARG A 1 14 ? -29.448 56.370 29.508 1.00 22.46 ? 67 ARG A NE 1 ATOM 95 C CZ . ARG A 1 14 ? -29.187 57.014 28.384 1.00 25.09 ? 67 ARG A CZ 1 ATOM 96 N NH1 . ARG A 1 14 ? -27.948 57.406 28.110 1.00 24.45 ? 67 ARG A NH1 1 ATOM 97 N NH2 . ARG A 1 14 ? -30.175 57.275 27.533 1.00 25.06 ? 67 ARG A NH2 1 ATOM 98 N N . LEU A 1 15 ? -28.635 59.155 32.345 1.00 19.57 ? 68 LEU A N 1 ATOM 99 C CA . LEU A 1 15 ? -27.637 60.048 31.778 1.00 19.22 ? 68 LEU A CA 1 ATOM 100 C C . LEU A 1 15 ? -26.713 60.589 32.864 1.00 19.86 ? 68 LEU A C 1 ATOM 101 O O . LEU A 1 15 ? -25.498 60.641 32.685 1.00 20.41 ? 68 LEU A O 1 ATOM 102 C CB . LEU A 1 15 ? -28.319 61.199 31.042 1.00 19.15 ? 68 LEU A CB 1 ATOM 103 C CG . LEU A 1 15 ? -29.017 60.801 29.735 1.00 19.00 ? 68 LEU A CG 1 ATOM 104 C CD1 . LEU A 1 15 ? -29.820 61.958 29.161 1.00 19.00 ? 68 LEU A CD1 1 ATOM 105 C CD2 . LEU A 1 15 ? -28.009 60.312 28.720 1.00 19.91 ? 68 LEU A CD2 1 ATOM 106 N N . ILE A 1 16 ? -27.300 60.972 33.995 1.00 21.69 ? 69 ILE A N 1 ATOM 107 C CA . ILE A 1 16 ? -26.554 61.508 35.121 1.00 20.61 ? 69 ILE A CA 1 ATOM 108 C C . ILE A 1 16 ? -25.577 60.499 35.692 1.00 21.66 ? 69 ILE A C 1 ATOM 109 O O . ILE A 1 16 ? -24.405 60.804 35.906 1.00 23.38 ? 69 ILE A O 1 ATOM 110 C CB . ILE A 1 16 ? -27.525 61.969 36.236 1.00 19.76 ? 69 ILE A CB 1 ATOM 111 C CG1 . ILE A 1 16 ? -28.487 63.028 35.698 1.00 18.74 ? 69 ILE A CG1 1 ATOM 112 C CG2 . ILE A 1 16 ? -26.736 62.540 37.404 1.00 20.06 ? 69 ILE A CG2 1 ATOM 113 C CD1 . ILE A 1 16 ? -29.671 63.320 36.611 1.00 18.56 ? 69 ILE A CD1 1 ATOM 114 N N . GLN A 1 17 ? -26.068 59.301 35.964 1.00 22.40 ? 70 GLN A N 1 ATOM 115 C CA . GLN A 1 17 ? -25.286 58.322 36.690 1.00 23.60 ? 70 GLN A CA 1 ATOM 116 C C . GLN A 1 17 ? -24.093 57.885 35.837 1.00 22.85 ? 70 GLN A C 1 ATOM 117 O O . GLN A 1 17 ? -23.043 57.546 36.366 1.00 23.24 ? 70 GLN A O 1 ATOM 118 C CB . GLN A 1 17 ? -26.150 57.132 37.103 1.00 25.38 ? 70 GLN A CB 1 ATOM 119 C CG . GLN A 1 17 ? -27.243 57.510 38.122 1.00 29.82 ? 70 GLN A CG 1 ATOM 120 C CD . GLN A 1 17 ? -28.341 56.455 38.266 1.00 31.65 ? 70 GLN A CD 1 ATOM 121 O OE1 . GLN A 1 17 ? -28.097 55.243 38.082 1.00 34.92 ? 70 GLN A OE1 1 ATOM 122 N NE2 . GLN A 1 17 ? -29.547 56.906 38.610 1.00 32.72 ? 70 GLN A NE2 1 ATOM 123 N N . ASN A 1 18 ? -24.249 57.906 34.518 1.00 22.93 ? 71 ASN A N 1 ATOM 124 C CA . ASN A 1 18 ? -23.184 57.450 33.634 1.00 22.88 ? 71 ASN A CA 1 ATOM 125 C C . ASN A 1 18 ? -22.069 58.494 33.511 1.00 21.63 ? 71 ASN A C 1 ATOM 126 O O . ASN A 1 18 ? -20.900 58.149 33.404 1.00 20.02 ? 71 ASN A O 1 ATOM 127 C CB . ASN A 1 18 ? -23.738 57.109 32.253 1.00 24.63 ? 71 ASN A CB 1 ATOM 128 C CG . ASN A 1 18 ? -24.464 55.783 32.226 1.00 27.79 ? 71 ASN A CG 1 ATOM 129 O OD1 . ASN A 1 18 ? -24.311 54.954 33.123 1.00 31.73 ? 71 ASN A OD1 1 ATOM 130 N ND2 . ASN A 1 18 ? -25.258 55.573 31.195 1.00 28.93 ? 71 ASN A ND2 1 ATOM 131 N N . MET A 1 19 ? -22.434 59.772 33.529 1.00 22.75 ? 72 MET A N 1 ATOM 132 C CA . MET A 1 19 ? -21.510 60.833 33.123 1.00 23.68 ? 72 MET A CA 1 ATOM 133 C C . MET A 1 19 ? -20.609 61.299 34.271 1.00 23.30 ? 72 MET A C 1 ATOM 134 O O . MET A 1 19 ? -20.954 61.152 35.429 1.00 22.61 ? 72 MET A O 1 ATOM 135 C CB . MET A 1 19 ? -22.291 62.009 32.537 1.00 24.29 ? 72 MET A CB 1 ATOM 136 C CG . MET A 1 19 ? -23.048 62.832 33.545 1.00 25.90 ? 72 MET A CG 1 ATOM 137 S SD . MET A 1 19 ? -24.054 64.072 32.715 1.00 25.68 ? 72 MET A SD 1 ATOM 138 C CE . MET A 1 19 ? -22.789 65.171 32.073 1.00 27.48 ? 72 MET A CE 1 ATOM 139 N N . ASP A 1 20 ? -19.434 61.832 33.951 1.00 27.09 ? 73 ASP A N 1 ATOM 140 C CA . ASP A 1 20 ? -18.602 62.485 34.965 1.00 29.13 ? 73 ASP A CA 1 ATOM 141 C C . ASP A 1 20 ? -18.436 63.952 34.634 1.00 31.26 ? 73 ASP A C 1 ATOM 142 O O . ASP A 1 20 ? -17.564 64.327 33.851 1.00 31.04 ? 73 ASP A O 1 ATOM 143 C CB . ASP A 1 20 ? -17.218 61.848 35.070 1.00 29.57 ? 73 ASP A CB 1 ATOM 144 C CG . ASP A 1 20 ? -16.244 62.693 35.898 1.00 29.57 ? 73 ASP A CG 1 ATOM 145 O OD1 . ASP A 1 20 ? -16.686 63.673 36.539 1.00 29.51 ? 73 ASP A OD1 1 ATOM 146 O OD2 . ASP A 1 20 ? -15.019 62.454 35.962 1.00 29.72 ? 73 ASP A OD2 1 ATOM 147 N N . ALA A 1 21 ? -19.275 64.780 35.238 1.00 32.39 ? 74 ALA A N 1 ATOM 148 C CA . ALA A 1 21 ? -19.326 66.181 34.881 1.00 34.24 ? 74 ALA A CA 1 ATOM 149 C C . ALA A 1 21 ? -18.107 66.900 35.468 1.00 35.93 ? 74 ALA A C 1 ATOM 150 O O . ALA A 1 21 ? -17.907 68.084 35.230 1.00 35.51 ? 74 ALA A O 1 ATOM 151 C CB . ALA A 1 21 ? -20.623 66.803 35.375 1.00 34.50 ? 74 ALA A CB 1 ATOM 152 N N . THR A 1 22 ? -17.289 66.163 36.214 1.00 36.84 ? 75 THR A N 1 ATOM 153 C CA . THR A 1 22 ? -16.002 66.664 36.688 1.00 36.47 ? 75 THR A CA 1 ATOM 154 C C . THR A 1 22 ? -15.024 66.864 35.533 1.00 37.60 ? 75 THR A C 1 ATOM 155 O O . THR A 1 22 ? -14.018 67.561 35.672 1.00 36.37 ? 75 THR A O 1 ATOM 156 C CB . THR A 1 22 ? -15.397 65.680 37.704 1.00 35.46 ? 75 THR A CB 1 ATOM 157 O OG1 . THR A 1 22 ? -15.940 65.924 39.007 1.00 35.38 ? 75 THR A OG1 1 ATOM 158 C CG2 . THR A 1 22 ? -13.912 65.923 37.877 1.00 37.26 ? 75 THR A CG2 1 ATOM 159 N N . THR A 1 23 ? -15.318 66.229 34.401 1.00 37.85 ? 76 THR A N 1 ATOM 160 C CA . THR A 1 23 ? -14.417 66.244 33.254 1.00 36.23 ? 76 THR A CA 1 ATOM 161 C C . THR A 1 23 ? -14.899 67.215 32.182 1.00 33.79 ? 76 THR A C 1 ATOM 162 O O . THR A 1 23 ? -16.073 67.229 31.812 1.00 34.30 ? 76 THR A O 1 ATOM 163 C CB . THR A 1 23 ? -14.274 64.821 32.654 1.00 36.44 ? 76 THR A CB 1 ATOM 164 O OG1 . THR A 1 23 ? -13.460 64.005 33.504 1.00 36.30 ? 76 THR A OG1 1 ATOM 165 C CG2 . THR A 1 23 ? -13.501 64.850 31.328 1.00 37.02 ? 76 THR A CG2 1 ATOM 166 N N . GLU A 1 24 ? -13.973 68.020 31.677 1.00 31.51 ? 77 GLU A N 1 ATOM 167 C CA . GLU A 1 24 ? -14.241 68.894 30.543 1.00 29.16 ? 77 GLU A CA 1 ATOM 168 C C . GLU A 1 24 ? -14.560 68.113 29.269 1.00 26.93 ? 77 GLU A C 1 ATOM 169 O O . GLU A 1 24 ? -13.694 67.462 28.696 1.00 24.41 ? 77 GLU A O 1 ATOM 170 C CB . GLU A 1 24 ? -13.031 69.790 30.297 1.00 32.71 ? 77 GLU A CB 1 ATOM 171 C CG . GLU A 1 24 ? -13.114 70.595 29.012 1.00 33.14 ? 77 GLU A CG 1 ATOM 172 C CD . GLU A 1 24 ? -14.312 71.505 29.002 1.00 33.43 ? 77 GLU A CD 1 ATOM 173 O OE1 . GLU A 1 24 ? -15.006 71.571 27.957 1.00 32.32 ? 77 GLU A OE1 1 ATOM 174 O OE2 . GLU A 1 24 ? -14.563 72.140 30.052 1.00 34.66 ? 77 GLU A OE2 1 ATOM 175 N N . PRO A 1 25 ? -15.804 68.206 28.821 1.00 26.23 ? 78 PRO A N 1 ATOM 176 C CA . PRO A 1 25 ? -16.248 67.564 27.585 1.00 27.80 ? 78 PRO A CA 1 ATOM 177 C C . PRO A 1 25 ? -15.287 67.773 26.416 1.00 29.63 ? 78 PRO A C 1 ATOM 178 O O . PRO A 1 25 ? -15.228 66.933 25.510 1.00 27.51 ? 78 PRO A O 1 ATOM 179 C CB . PRO A 1 25 ? -17.588 68.248 27.290 1.00 26.54 ? 78 PRO A CB 1 ATOM 180 C CG . PRO A 1 25 ? -17.747 69.301 28.312 1.00 27.00 ? 78 PRO A CG 1 ATOM 181 C CD . PRO A 1 25 ? -16.891 68.943 29.474 1.00 28.00 ? 78 PRO A CD 1 ATOM 182 N N . CYS A 1 26 ? -14.548 68.877 26.434 1.00 28.24 ? 79 CYS A N 1 ATOM 183 C CA . CYS A 1 26 ? -13.727 69.237 25.287 1.00 28.97 ? 79 CYS A CA 1 ATOM 184 C C . CYS A 1 26 ? -12.322 68.673 25.426 1.00 26.79 ? 79 CYS A C 1 ATOM 185 O O . CYS A 1 26 ? -11.583 68.600 24.446 1.00 27.67 ? 79 CYS A O 1 ATOM 186 C CB . CYS A 1 26 ? -13.679 70.754 25.113 1.00 29.82 ? 79 CYS A CB 1 ATOM 187 S SG . CYS A 1 26 ? -15.254 71.457 24.595 1.00 29.68 ? 79 CYS A SG 1 ATOM 188 N N . THR A 1 27 ? -11.968 68.276 26.647 1.00 25.87 ? 80 THR A N 1 ATOM 189 C CA . THR A 1 27 ? -10.721 67.565 26.914 1.00 26.77 ? 80 THR A CA 1 ATOM 190 C C . THR A 1 27 ? -10.860 66.061 26.649 1.00 24.47 ? 80 THR A C 1 ATOM 191 O O . THR A 1 27 ? -10.042 65.474 25.957 1.00 21.95 ? 80 THR A O 1 ATOM 192 C CB . THR A 1 27 ? -10.272 67.802 28.383 1.00 30.16 ? 80 THR A CB 1 ATOM 193 O OG1 . THR A 1 27 ? -9.995 69.194 28.604 1.00 31.75 ? 80 THR A OG1 1 ATOM 194 C CG2 . THR A 1 27 ? -8.948 67.108 28.675 1.00 29.82 ? 80 THR A CG2 1 ATOM 195 N N . ASP A 1 28 ? -11.897 65.430 27.186 1.00 25.13 ? 81 ASP A N 1 ATOM 196 C CA . ASP A 1 28 ? -12.100 64.002 26.916 1.00 25.00 ? 81 ASP A CA 1 ATOM 197 C C . ASP A 1 28 ? -13.556 63.552 27.031 1.00 24.31 ? 81 ASP A C 1 ATOM 198 O O . ASP A 1 28 ? -13.999 63.148 28.104 1.00 26.09 ? 81 ASP A O 1 ATOM 199 C CB . ASP A 1 28 ? -11.236 63.181 27.863 1.00 24.16 ? 81 ASP A CB 1 ATOM 200 C CG . ASP A 1 28 ? -11.318 61.705 27.587 1.00 25.65 ? 81 ASP A CG 1 ATOM 201 O OD1 . ASP A 1 28 ? -12.355 61.263 27.044 1.00 25.96 ? 81 ASP A OD1 1 ATOM 202 O OD2 . ASP A 1 28 ? -10.396 60.912 27.881 1.00 24.59 ? 81 ASP A OD2 1 ATOM 203 N N . PHE A 1 29 ? -14.292 63.588 25.921 1.00 25.15 ? 82 PHE A N 1 ATOM 204 C CA . PHE A 1 29 ? -15.747 63.466 25.977 1.00 24.74 ? 82 PHE A CA 1 ATOM 205 C C . PHE A 1 29 ? -16.216 62.066 26.363 1.00 24.28 ? 82 PHE A C 1 ATOM 206 O O . PHE A 1 29 ? -17.318 61.905 26.877 1.00 24.36 ? 82 PHE A O 1 ATOM 207 C CB . PHE A 1 29 ? -16.398 63.855 24.651 1.00 23.79 ? 82 PHE A CB 1 ATOM 208 C CG . PHE A 1 29 ? -17.889 64.061 24.755 1.00 26.56 ? 82 PHE A CG 1 ATOM 209 C CD1 . PHE A 1 29 ? -18.405 65.231 25.292 1.00 27.55 ? 82 PHE A CD1 1 ATOM 210 C CD2 . PHE A 1 29 ? -18.772 63.079 24.338 1.00 25.83 ? 82 PHE A CD2 1 ATOM 211 C CE1 . PHE A 1 29 ? -19.771 65.418 25.389 1.00 28.73 ? 82 PHE A CE1 1 ATOM 212 C CE2 . PHE A 1 29 ? -20.132 63.263 24.436 1.00 25.41 ? 82 PHE A CE2 1 ATOM 213 C CZ . PHE A 1 29 ? -20.636 64.429 24.958 1.00 27.22 ? 82 PHE A CZ 1 ATOM 214 N N . PHE A 1 30 ? -15.398 61.057 26.100 1.00 23.31 ? 83 PHE A N 1 ATOM 215 C CA . PHE A 1 30 ? -15.680 59.718 26.611 1.00 26.99 ? 83 PHE A CA 1 ATOM 216 C C . PHE A 1 30 ? -15.627 59.687 28.144 1.00 28.64 ? 83 PHE A C 1 ATOM 217 O O . PHE A 1 30 ? -16.520 59.140 28.789 1.00 27.37 ? 83 PHE A O 1 ATOM 218 C CB . PHE A 1 30 ? -14.716 58.686 26.025 1.00 25.85 ? 83 PHE A CB 1 ATOM 219 C CG . PHE A 1 30 ? -15.012 57.276 26.449 1.00 25.92 ? 83 PHE A CG 1 ATOM 220 C CD1 . PHE A 1 30 ? -14.165 56.605 27.305 1.00 27.32 ? 83 PHE A CD1 1 ATOM 221 C CD2 . PHE A 1 30 ? -16.128 56.623 25.982 1.00 26.26 ? 83 PHE A CD2 1 ATOM 222 C CE1 . PHE A 1 30 ? -14.433 55.304 27.692 1.00 29.18 ? 83 PHE A CE1 1 ATOM 223 C CE2 . PHE A 1 30 ? -16.407 55.329 26.370 1.00 27.69 ? 83 PHE A CE2 1 ATOM 224 C CZ . PHE A 1 30 ? -15.555 54.669 27.230 1.00 27.57 ? 83 PHE A CZ 1 ATOM 225 N N . LYS A 1 31 ? -14.586 60.285 28.722 1.00 30.84 ? 84 LYS A N 1 ATOM 226 C CA . LYS A 1 31 ? -14.500 60.428 30.175 1.00 29.42 ? 84 LYS A CA 1 ATOM 227 C C . LYS A 1 31 ? -15.726 61.164 30.692 1.00 24.99 ? 84 LYS A C 1 ATOM 228 O O . LYS A 1 31 ? -16.379 60.739 31.629 1.00 20.59 ? 84 LYS A O 1 ATOM 229 C CB . LYS A 1 31 ? -13.237 61.205 30.553 1.00 34.14 ? 84 LYS A CB 1 ATOM 230 C CG . LYS A 1 31 ? -12.373 60.557 31.647 1.00 38.20 ? 84 LYS A CG 1 ATOM 231 C CD . LYS A 1 31 ? -11.344 61.556 32.220 1.00 40.05 ? 84 LYS A CD 1 ATOM 232 C CE . LYS A 1 31 ? -10.232 60.857 33.004 1.00 42.66 ? 84 LYS A CE 1 ATOM 233 N NZ . LYS A 1 31 ? -8.865 60.980 32.369 1.00 42.25 ? 84 LYS A NZ 1 ATOM 234 N N . TYR A 1 32 ? -16.028 62.288 30.067 1.00 24.85 ? 85 TYR A N 1 ATOM 235 C CA . TYR A 1 32 ? -17.138 63.123 30.484 1.00 24.08 ? 85 TYR A CA 1 ATOM 236 C C . TYR A 1 32 ? -18.443 62.339 30.449 1.00 25.22 ? 85 TYR A C 1 ATOM 237 O O . TYR A 1 32 ? -19.228 62.373 31.395 1.00 25.56 ? 85 TYR A O 1 ATOM 238 C CB . TYR A 1 32 ? -17.232 64.337 29.567 1.00 21.78 ? 85 TYR A CB 1 ATOM 239 C CG . TYR A 1 32 ? -18.473 65.167 29.757 1.00 21.78 ? 85 TYR A CG 1 ATOM 240 C CD1 . TYR A 1 32 ? -18.568 66.091 30.785 1.00 22.70 ? 85 TYR A CD1 1 ATOM 241 C CD2 . TYR A 1 32 ? -19.553 65.028 28.895 1.00 21.98 ? 85 TYR A CD2 1 ATOM 242 C CE1 . TYR A 1 32 ? -19.714 66.857 30.951 1.00 24.65 ? 85 TYR A CE1 1 ATOM 243 C CE2 . TYR A 1 32 ? -20.694 65.776 29.049 1.00 20.81 ? 85 TYR A CE2 1 ATOM 244 C CZ . TYR A 1 32 ? -20.778 66.691 30.068 1.00 23.84 ? 85 TYR A CZ 1 ATOM 245 O OH . TYR A 1 32 ? -21.935 67.430 30.213 1.00 22.81 ? 85 TYR A OH 1 ATOM 246 N N . ALA A 1 33 ? -18.676 61.645 29.344 1.00 23.20 ? 86 ALA A N 1 ATOM 247 C CA . ALA A 1 33 ? -19.971 61.051 29.087 1.00 22.09 ? 86 ALA A CA 1 ATOM 248 C C . ALA A 1 33 ? -20.095 59.735 29.834 1.00 20.57 ? 86 ALA A C 1 ATOM 249 O O . ALA A 1 33 ? -21.198 59.267 30.086 1.00 18.37 ? 86 ALA A O 1 ATOM 250 C CB . ALA A 1 33 ? -20.159 60.830 27.597 1.00 25.34 ? 86 ALA A CB 1 ATOM 251 N N . CYS A 1 34 ? -18.960 59.150 30.203 1.00 18.04 ? 87 CYS A N 1 ATOM 252 C CA . CYS A 1 34 ? -18.948 57.774 30.655 1.00 19.06 ? 87 CYS A CA 1 ATOM 253 C C . CYS A 1 34 ? -18.255 57.570 31.988 1.00 17.98 ? 87 CYS A C 1 ATOM 254 O O . CYS A 1 34 ? -18.181 56.452 32.477 1.00 11.29 ? 87 CYS A O 1 ATOM 255 C CB . CYS A 1 34 ? -18.314 56.887 29.595 1.00 19.33 ? 87 CYS A CB 1 ATOM 256 S SG . CYS A 1 34 ? -19.453 56.646 28.248 1.00 20.59 ? 87 CYS A SG 1 ATOM 257 N N . GLY A 1 35 ? -17.785 58.656 32.586 1.00 22.35 ? 88 GLY A N 1 ATOM 258 C CA . GLY A 1 35 ? -16.827 58.567 33.674 1.00 25.39 ? 88 GLY A CA 1 ATOM 259 C C . GLY A 1 35 ? -17.405 57.839 34.872 1.00 26.12 ? 88 GLY A C 1 ATOM 260 O O . GLY A 1 35 ? -16.696 57.109 35.574 1.00 25.94 ? 88 GLY A O 1 ATOM 261 N N . GLY A 1 36 ? -18.696 58.048 35.108 1.00 24.48 ? 89 GLY A N 1 ATOM 262 C CA . GLY A 1 36 ? -19.352 57.516 36.290 1.00 24.84 ? 89 GLY A CA 1 ATOM 263 C C . GLY A 1 36 ? -19.670 56.043 36.140 1.00 22.71 ? 89 GLY A C 1 ATOM 264 O O . GLY A 1 36 ? -19.611 55.276 37.105 1.00 20.33 ? 89 GLY A O 1 ATOM 265 N N . TRP A 1 37 ? -19.982 55.642 34.913 1.00 21.00 ? 90 TRP A N 1 ATOM 266 C CA . TRP A 1 37 ? -20.083 54.231 34.584 1.00 17.50 ? 90 TRP A CA 1 ATOM 267 C C . TRP A 1 37 ? -18.761 53.525 34.860 1.00 18.40 ? 90 TRP A C 1 ATOM 268 O O . TRP A 1 37 ? -18.727 52.461 35.491 1.00 20.13 ? 90 TRP A O 1 ATOM 269 C CB . TRP A 1 37 ? -20.525 54.033 33.121 1.00 15.76 ? 90 TRP A CB 1 ATOM 270 C CG . TRP A 1 37 ? -20.946 52.630 32.871 1.00 16.50 ? 90 TRP A CG 1 ATOM 271 C CD1 . TRP A 1 37 ? -22.221 52.124 32.930 1.00 19.42 ? 90 TRP A CD1 1 ATOM 272 C CD2 . TRP A 1 37 ? -20.097 51.529 32.585 1.00 15.97 ? 90 TRP A CD2 1 ATOM 273 N NE1 . TRP A 1 37 ? -22.204 50.773 32.688 1.00 17.14 ? 90 TRP A NE1 1 ATOM 274 C CE2 . TRP A 1 37 ? -20.911 50.382 32.474 1.00 19.53 ? 90 TRP A CE2 1 ATOM 275 C CE3 . TRP A 1 37 ? -18.721 51.387 32.411 1.00 16.75 ? 90 TRP A CE3 1 ATOM 276 C CZ2 . TRP A 1 37 ? -20.391 49.120 32.200 1.00 18.50 ? 90 TRP A CZ2 1 ATOM 277 C CZ3 . TRP A 1 37 ? -18.216 50.147 32.139 1.00 20.26 ? 90 TRP A CZ3 1 ATOM 278 C CH2 . TRP A 1 37 ? -19.049 49.025 32.029 1.00 18.63 ? 90 TRP A CH2 1 ATOM 279 N N . LEU A 1 38 ? -17.670 54.113 34.383 1.00 21.03 ? 91 LEU A N 1 ATOM 280 C CA . LEU A 1 38 ? -16.346 53.527 34.544 1.00 24.33 ? 91 LEU A CA 1 ATOM 281 C C . LEU A 1 38 ? -16.007 53.309 36.019 1.00 24.55 ? 91 LEU A C 1 ATOM 282 O O . LEU A 1 38 ? -15.421 52.293 36.388 1.00 22.41 ? 91 LEU A O 1 ATOM 283 C CB . LEU A 1 38 ? -15.286 54.417 33.911 1.00 26.12 ? 91 LEU A CB 1 ATOM 284 C CG . LEU A 1 38 ? -15.049 54.294 32.404 1.00 29.43 ? 91 LEU A CG 1 ATOM 285 C CD1 . LEU A 1 38 ? -15.439 52.924 31.854 1.00 27.86 ? 91 LEU A CD1 1 ATOM 286 C CD2 . LEU A 1 38 ? -15.773 55.408 31.663 1.00 29.90 ? 91 LEU A CD2 1 ATOM 287 N N . LYS A 1 39 ? -16.380 54.257 36.864 1.00 26.73 ? 92 LYS A N 1 ATOM 288 C CA . LYS A 1 39 ? -16.050 54.164 38.278 1.00 31.15 ? 92 LYS A CA 1 ATOM 289 C C . LYS A 1 39 ? -16.786 53.017 38.951 1.00 30.90 ? 92 LYS A C 1 ATOM 290 O O . LYS A 1 39 ? -16.216 52.308 39.780 1.00 34.43 ? 92 LYS A O 1 ATOM 291 C CB . LYS A 1 39 ? -16.385 55.462 39.001 1.00 34.17 ? 92 LYS A CB 1 ATOM 292 C CG . LYS A 1 39 ? -15.960 55.461 40.455 1.00 37.40 ? 92 LYS A CG 1 ATOM 293 C CD . LYS A 1 39 ? -17.137 55.644 41.399 1.00 40.07 ? 92 LYS A CD 1 ATOM 294 C CE . LYS A 1 39 ? -16.654 55.797 42.840 1.00 41.14 ? 92 LYS A CE 1 ATOM 295 N NZ . LYS A 1 39 ? -15.236 56.275 42.873 1.00 42.44 ? 92 LYS A NZ 1 ATOM 296 N N . ARG A 1 40 ? -18.051 52.830 38.594 1.00 31.40 ? 93 ARG A N 1 ATOM 297 C CA . ARG A 1 40 ? -18.962 52.051 39.421 1.00 33.56 ? 93 ARG A CA 1 ATOM 298 C C . ARG A 1 40 ? -18.904 50.567 39.024 1.00 31.09 ? 93 ARG A C 1 ATOM 299 O O . ARG A 1 40 ? -19.235 49.686 39.820 1.00 30.87 ? 93 ARG A O 1 ATOM 300 C CB . ARG A 1 40 ? -20.390 52.614 39.323 1.00 36.00 ? 93 ARG A CB 1 ATOM 301 C CG . ARG A 1 40 ? -20.639 53.806 40.242 1.00 41.44 ? 93 ARG A CG 1 ATOM 302 C CD . ARG A 1 40 ? -22.083 54.319 40.251 1.00 46.34 ? 93 ARG A CD 1 ATOM 303 N NE . ARG A 1 40 ? -22.177 55.739 39.894 1.00 49.72 ? 93 ARG A NE 1 ATOM 304 C CZ . ARG A 1 40 ? -23.099 56.584 40.357 1.00 53.42 ? 93 ARG A CZ 1 ATOM 305 N NH1 . ARG A 1 40 ? -24.032 56.172 41.207 1.00 53.75 ? 93 ARG A NH1 1 ATOM 306 N NH2 . ARG A 1 40 ? -23.091 57.852 39.965 1.00 54.77 ? 93 ARG A NH2 1 ATOM 307 N N . ASN A 1 41 ? -18.466 50.299 37.797 1.00 26.04 ? 94 ASN A N 1 ATOM 308 C CA . ASN A 1 41 ? -18.639 48.983 37.202 1.00 23.25 ? 94 ASN A CA 1 ATOM 309 C C . ASN A 1 41 ? -17.296 48.310 37.101 1.00 23.82 ? 94 ASN A C 1 ATOM 310 O O . ASN A 1 41 ? -16.314 48.942 36.742 1.00 23.33 ? 94 ASN A O 1 ATOM 311 C CB . ASN A 1 41 ? -19.269 49.086 35.814 1.00 22.69 ? 94 ASN A CB 1 ATOM 312 C CG . ASN A 1 41 ? -20.766 49.287 35.869 1.00 22.28 ? 94 ASN A CG 1 ATOM 313 O OD1 . ASN A 1 41 ? -21.518 48.340 36.096 1.00 24.47 ? 94 ASN A OD1 1 ATOM 314 N ND2 . ASN A 1 41 ? -21.210 50.531 35.678 1.00 22.24 ? 94 ASN A ND2 1 ATOM 315 N N . VAL A 1 42 ? -17.242 47.030 37.440 1.00 24.70 ? 95 VAL A N 1 ATOM 316 C CA . VAL A 1 42 ? -16.109 46.206 37.076 1.00 24.59 ? 95 VAL A CA 1 ATOM 317 C C . VAL A 1 42 ? -16.578 45.140 36.086 1.00 24.72 ? 95 VAL A C 1 ATOM 318 O O . VAL A 1 42 ? -17.692 44.632 36.194 1.00 26.60 ? 95 VAL A O 1 ATOM 319 C CB . VAL A 1 42 ? -15.498 45.559 38.321 1.00 27.94 ? 95 VAL A CB 1 ATOM 320 C CG1 . VAL A 1 42 ? -14.456 44.514 37.934 1.00 30.30 ? 95 VAL A CG1 1 ATOM 321 C CG2 . VAL A 1 42 ? -14.881 46.614 39.222 1.00 29.78 ? 95 VAL A CG2 1 ATOM 322 N N . ILE A 1 43 ? -15.740 44.812 35.112 1.00 22.14 ? 96 ILE A N 1 ATOM 323 C CA . ILE A 1 43 ? -16.053 43.737 34.191 1.00 20.09 ? 96 ILE A CA 1 ATOM 324 C C . ILE A 1 43 ? -16.294 42.452 34.967 1.00 19.62 ? 96 ILE A C 1 ATOM 325 O O . ILE A 1 43 ? -15.450 42.031 35.739 1.00 17.64 ? 96 ILE A O 1 ATOM 326 C CB . ILE A 1 43 ? -14.913 43.525 33.217 1.00 19.49 ? 96 ILE A CB 1 ATOM 327 C CG1 . ILE A 1 43 ? -14.454 44.868 32.659 1.00 22.98 ? 96 ILE A CG1 1 ATOM 328 C CG2 . ILE A 1 43 ? -15.355 42.581 32.102 1.00 20.34 ? 96 ILE A CG2 1 ATOM 329 C CD1 . ILE A 1 43 ? -13.238 44.778 31.729 1.00 23.63 ? 96 ILE A CD1 1 ATOM 330 N N . PRO A 1 44 ? -17.450 41.836 34.759 1.00 20.30 ? 97 PRO A N 1 ATOM 331 C CA . PRO A 1 44 ? -17.731 40.503 35.301 1.00 18.04 ? 97 PRO A CA 1 ATOM 332 C C . PRO A 1 44 ? -16.712 39.467 34.840 1.00 18.22 ? 97 PRO A C 1 ATOM 333 O O . PRO A 1 44 ? -16.135 39.596 33.764 1.00 17.68 ? 97 PRO A O 1 ATOM 334 C CB . PRO A 1 44 ? -19.127 40.182 34.755 1.00 18.99 ? 97 PRO A CB 1 ATOM 335 C CG . PRO A 1 44 ? -19.737 41.506 34.463 1.00 20.49 ? 97 PRO A CG 1 ATOM 336 C CD . PRO A 1 44 ? -18.596 42.400 34.027 1.00 20.21 ? 97 PRO A CD 1 ATOM 337 N N . GLU A 1 45 ? -16.504 38.450 35.667 1.00 17.25 ? 98 GLU A N 1 ATOM 338 C CA . GLU A 1 45 ? -15.572 37.361 35.369 1.00 20.18 ? 98 GLU A CA 1 ATOM 339 C C . GLU A 1 45 ? -15.919 36.593 34.084 1.00 17.38 ? 98 GLU A C 1 ATOM 340 O O . GLU A 1 45 ? -15.059 35.991 33.459 1.00 16.10 ? 98 GLU A O 1 ATOM 341 C CB . GLU A 1 45 ? -15.524 36.395 36.562 1.00 20.50 ? 98 GLU A CB 1 ATOM 342 C CG . GLU A 1 45 ? -15.079 37.074 37.853 1.00 20.81 ? 98 GLU A CG 1 ATOM 343 C CD . GLU A 1 45 ? -13.730 37.753 37.706 1.00 18.67 ? 98 GLU A CD 1 ATOM 344 O OE1 . GLU A 1 45 ? -12.738 37.046 37.548 1.00 18.32 ? 98 GLU A OE1 1 ATOM 345 O OE2 . GLU A 1 45 ? -13.664 39.000 37.746 1.00 23.26 ? 98 GLU A OE2 1 ATOM 346 N N . THR A 1 46 ? -17.181 36.642 33.691 1.00 17.14 ? 99 THR A N 1 ATOM 347 C CA . THR A 1 46 ? -17.641 35.899 32.541 1.00 13.49 ? 99 THR A CA 1 ATOM 348 C C . THR A 1 46 ? -17.693 36.810 31.335 1.00 13.17 ? 99 THR A C 1 ATOM 349 O O . THR A 1 46 ? -18.175 36.400 30.291 1.00 13.57 ? 99 THR A O 1 ATOM 350 C CB . THR A 1 46 ? -19.052 35.357 32.783 1.00 12.33 ? 99 THR A CB 1 ATOM 351 O OG1 . THR A 1 46 ? -19.926 36.448 33.097 1.00 17.05 ? 99 THR A OG1 1 ATOM 352 C CG2 . THR A 1 46 ? -19.128 34.468 34.006 1.00 12.29 ? 99 THR A CG2 1 ATOM 353 N N . SER A 1 47 ? -17.255 38.060 31.492 1.00 13.41 ? 100 SER A N 1 ATOM 354 C CA . SER A 1 47 ? -17.335 39.052 30.412 1.00 13.78 ? 100 SER A CA 1 ATOM 355 C C . SER A 1 47 ? -15.938 39.320 29.845 1.00 13.56 ? 100 SER A C 1 ATOM 356 O O . SER A 1 47 ? -14.965 39.482 30.594 1.00 10.47 ? 100 SER A O 1 ATOM 357 C CB . SER A 1 47 ? -17.911 40.385 30.925 1.00 15.58 ? 100 SER A CB 1 ATOM 358 O OG . SER A 1 47 ? -19.333 40.412 31.013 1.00 14.29 ? 100 SER A OG 1 ATOM 359 N N . SER A 1 48 ? -15.819 39.365 28.527 1.00 12.57 ? 101 SER A N 1 ATOM 360 C CA . SER A 1 48 ? -14.593 39.864 27.939 1.00 13.86 ? 101 SER A CA 1 ATOM 361 C C . SER A 1 48 ? -14.717 41.354 27.657 1.00 14.68 ? 101 SER A C 1 ATOM 362 O O . SER A 1 48 ? -13.725 42.063 27.577 1.00 16.31 ? 101 SER A O 1 ATOM 363 C CB . SER A 1 48 ? -14.260 39.096 26.681 1.00 16.31 ? 101 SER A CB 1 ATOM 364 O OG . SER A 1 48 ? -15.342 39.141 25.793 1.00 22.50 ? 101 SER A OG 1 ATOM 365 N N . ARG A 1 49 ? -15.949 41.827 27.538 1.00 17.57 ? 102 ARG A N 1 ATOM 366 C CA . ARG A 1 49 ? -16.206 43.242 27.370 1.00 21.93 ? 102 ARG A CA 1 ATOM 367 C C . ARG A 1 49 ? -17.497 43.563 28.102 1.00 20.64 ? 102 ARG A C 1 ATOM 368 O O . ARG A 1 49 ? -18.422 42.763 28.117 1.00 18.05 ? 102 ARG A O 1 ATOM 369 C CB . ARG A 1 49 ? -16.307 43.582 25.881 1.00 23.62 ? 102 ARG A CB 1 ATOM 370 C CG . ARG A 1 49 ? -16.798 44.981 25.574 1.00 26.17 ? 102 ARG A CG 1 ATOM 371 C CD . ARG A 1 49 ? -17.114 45.217 24.084 1.00 25.39 ? 102 ARG A CD 1 ATOM 372 N NE . ARG A 1 49 ? -18.384 44.605 23.719 1.00 27.45 ? 102 ARG A NE 1 ATOM 373 C CZ . ARG A 1 49 ? -18.778 44.351 22.476 1.00 27.70 ? 102 ARG A CZ 1 ATOM 374 N NH1 . ARG A 1 49 ? -18.003 44.649 21.451 1.00 29.29 ? 102 ARG A NH1 1 ATOM 375 N NH2 . ARG A 1 49 ? -19.951 43.780 22.263 1.00 28.28 ? 102 ARG A NH2 1 ATOM 376 N N . TYR A 1 50 ? -17.555 44.731 28.725 1.00 17.97 ? 103 TYR A N 1 ATOM 377 C CA . TYR A 1 50 ? -18.760 45.136 29.416 1.00 17.76 ? 103 TYR A CA 1 ATOM 378 C C . TYR A 1 50 ? -18.996 46.589 29.127 1.00 15.23 ? 103 TYR A C 1 ATOM 379 O O . TYR A 1 50 ? -18.070 47.342 28.874 1.00 21.51 ? 103 TYR A O 1 ATOM 380 C CB . TYR A 1 50 ? -18.606 44.898 30.917 1.00 19.05 ? 103 TYR A CB 1 ATOM 381 C CG . TYR A 1 50 ? -19.893 44.713 31.690 1.00 19.47 ? 103 TYR A CG 1 ATOM 382 C CD1 . TYR A 1 50 ? -20.813 43.741 31.342 1.00 19.56 ? 103 TYR A CD1 1 ATOM 383 C CD2 . TYR A 1 50 ? -20.155 45.482 32.811 1.00 19.20 ? 103 TYR A CD2 1 ATOM 384 C CE1 . TYR A 1 50 ? -21.978 43.561 32.076 1.00 18.45 ? 103 TYR A CE1 1 ATOM 385 C CE2 . TYR A 1 50 ? -21.302 45.308 33.546 1.00 20.91 ? 103 TYR A CE2 1 ATOM 386 C CZ . TYR A 1 50 ? -22.214 44.349 33.180 1.00 21.37 ? 103 TYR A CZ 1 ATOM 387 O OH . TYR A 1 50 ? -23.366 44.202 33.931 1.00 23.56 ? 103 TYR A OH 1 ATOM 388 N N . GLY A 1 51 ? -20.250 46.987 29.156 1.00 19.88 ? 104 GLY A N 1 ATOM 389 C CA . GLY A 1 51 ? -20.635 48.287 28.654 1.00 19.97 ? 104 GLY A CA 1 ATOM 390 C C . GLY A 1 51 ? -22.134 48.299 28.476 1.00 22.03 ? 104 GLY A C 1 ATOM 391 O O . GLY A 1 51 ? -22.776 47.245 28.552 1.00 18.29 ? 104 GLY A O 1 ATOM 392 N N . ASN A 1 52 ? -22.690 49.490 28.266 1.00 21.66 ? 105 ASN A N 1 ATOM 393 C CA . ASN A 1 52 ? -24.124 49.659 28.181 1.00 22.59 ? 105 ASN A CA 1 ATOM 394 C C . ASN A 1 52 ? -24.707 48.750 27.099 1.00 23.45 ? 105 ASN A C 1 ATOM 395 O O . ASN A 1 52 ? -25.769 48.169 27.257 1.00 25.84 ? 105 ASN A O 1 ATOM 396 C CB . ASN A 1 52 ? -24.464 51.129 27.905 1.00 25.07 ? 105 ASN A CB 1 ATOM 397 C CG . ASN A 1 52 ? -24.434 52.007 29.174 1.00 26.89 ? 105 ASN A CG 1 ATOM 398 O OD1 . ASN A 1 52 ? -24.188 53.209 29.085 1.00 29.41 ? 105 ASN A OD1 1 ATOM 399 N ND2 . ASN A 1 52 ? -24.701 51.412 30.346 1.00 23.11 ? 105 ASN A ND2 1 ATOM 400 N N . PHE A 1 53 ? -23.989 48.613 25.999 1.00 23.50 ? 106 PHE A N 1 ATOM 401 C CA . PHE A 1 53 ? -24.437 47.801 24.891 1.00 21.70 ? 106 PHE A CA 1 ATOM 402 C C . PHE A 1 53 ? -24.497 46.327 25.279 1.00 22.56 ? 106 PHE A C 1 ATOM 403 O O . PHE A 1 53 ? -25.492 45.640 25.027 1.00 19.83 ? 106 PHE A O 1 ATOM 404 C CB . PHE A 1 53 ? -23.474 48.009 23.729 1.00 27.31 ? 106 PHE A CB 1 ATOM 405 C CG . PHE A 1 53 ? -23.943 47.431 22.437 1.00 25.30 ? 106 PHE A CG 1 ATOM 406 C CD1 . PHE A 1 53 ? -24.916 48.070 21.695 1.00 27.74 ? 106 PHE A CD1 1 ATOM 407 C CD2 . PHE A 1 53 ? -23.396 46.269 21.960 1.00 26.29 ? 106 PHE A CD2 1 ATOM 408 C CE1 . PHE A 1 53 ? -25.356 47.545 20.518 1.00 25.55 ? 106 PHE A CE1 1 ATOM 409 C CE2 . PHE A 1 53 ? -23.819 45.740 20.773 1.00 28.38 ? 106 PHE A CE2 1 ATOM 410 C CZ . PHE A 1 53 ? -24.807 46.381 20.051 1.00 29.30 ? 106 PHE A CZ 1 ATOM 411 N N . ASP A 1 54 ? -23.439 45.826 25.906 1.00 20.49 ? 107 ASP A N 1 ATOM 412 C CA . ASP A 1 54 ? -23.461 44.449 26.398 1.00 18.88 ? 107 ASP A CA 1 ATOM 413 C C . ASP A 1 54 ? -24.550 44.239 27.473 1.00 19.06 ? 107 ASP A C 1 ATOM 414 O O . ASP A 1 54 ? -25.212 43.205 27.495 1.00 19.43 ? 107 ASP A O 1 ATOM 415 C CB . ASP A 1 54 ? -22.082 44.037 26.934 1.00 18.62 ? 107 ASP A CB 1 ATOM 416 C CG . ASP A 1 54 ? -21.024 43.937 25.831 1.00 19.32 ? 107 ASP A CG 1 ATOM 417 O OD1 . ASP A 1 54 ? -21.251 43.226 24.836 1.00 22.60 ? 107 ASP A OD1 1 ATOM 418 O OD2 . ASP A 1 54 ? -19.931 44.530 25.871 1.00 18.27 ? 107 ASP A OD2 1 ATOM 419 N N . ILE A 1 55 ? -24.746 45.218 28.351 1.00 16.49 ? 108 ILE A N 1 ATOM 420 C CA . ILE A 1 55 ? -25.771 45.098 29.379 1.00 18.77 ? 108 ILE A CA 1 ATOM 421 C C . ILE A 1 55 ? -27.152 44.860 28.758 1.00 17.65 ? 108 ILE A C 1 ATOM 422 O O . ILE A 1 55 ? -27.912 43.991 29.208 1.00 18.38 ? 108 ILE A O 1 ATOM 423 C CB . ILE A 1 55 ? -25.774 46.347 30.302 1.00 20.80 ? 108 ILE A CB 1 ATOM 424 C CG1 . ILE A 1 55 ? -24.522 46.349 31.176 1.00 20.89 ? 108 ILE A CG1 1 ATOM 425 C CG2 . ILE A 1 55 ? -27.043 46.386 31.194 1.00 18.74 ? 108 ILE A CG2 1 ATOM 426 C CD1 . ILE A 1 55 ? -24.389 47.579 32.023 1.00 21.96 ? 108 ILE A CD1 1 ATOM 427 N N . LEU A 1 56 ? -27.474 45.604 27.709 1.00 21.07 ? 109 LEU A N 1 ATOM 428 C CA . LEU A 1 56 ? -28.694 45.332 26.940 1.00 22.12 ? 109 LEU A CA 1 ATOM 429 C C . LEU A 1 56 ? -28.789 43.869 26.516 1.00 20.61 ? 109 LEU A C 1 ATOM 430 O O . LEU A 1 56 ? -29.846 43.252 26.601 1.00 20.23 ? 109 LEU A O 1 ATOM 431 C CB . LEU A 1 56 ? -28.733 46.200 25.703 1.00 22.81 ? 109 LEU A CB 1 ATOM 432 C CG . LEU A 1 56 ? -29.083 47.649 25.957 1.00 24.70 ? 109 LEU A CG 1 ATOM 433 C CD1 . LEU A 1 56 ? -29.775 48.203 24.725 1.00 27.53 ? 109 LEU A CD1 1 ATOM 434 C CD2 . LEU A 1 56 ? -29.961 47.762 27.182 1.00 25.54 ? 109 LEU A CD2 1 ATOM 435 N N . ARG A 1 57 ? -27.676 43.314 26.056 1.00 20.53 ? 110 ARG A N 1 ATOM 436 C CA . ARG A 1 57 ? -27.675 41.935 25.608 1.00 23.35 ? 110 ARG A CA 1 ATOM 437 C C . ARG A 1 57 ? -27.868 40.978 26.779 1.00 20.63 ? 110 ARG A C 1 ATOM 438 O O . ARG A 1 57 ? -28.480 39.920 26.617 1.00 18.12 ? 110 ARG A O 1 ATOM 439 C CB . ARG A 1 57 ? -26.391 41.611 24.855 1.00 24.36 ? 110 ARG A CB 1 ATOM 440 C CG . ARG A 1 57 ? -26.435 41.974 23.383 1.00 27.69 ? 110 ARG A CG 1 ATOM 441 C CD . ARG A 1 57 ? -25.079 41.892 22.702 1.00 29.97 ? 110 ARG A CD 1 ATOM 442 N NE . ARG A 1 57 ? -25.089 42.355 21.315 1.00 31.00 ? 110 ARG A NE 1 ATOM 443 C CZ . ARG A 1 57 ? -24.024 42.296 20.518 1.00 31.43 ? 110 ARG A CZ 1 ATOM 444 N NH1 . ARG A 1 57 ? -22.882 41.798 20.981 1.00 29.65 ? 110 ARG A NH1 1 ATOM 445 N NH2 . ARG A 1 57 ? -24.091 42.735 19.266 1.00 31.52 ? 110 ARG A NH2 1 ATOM 446 N N . ASP A 1 58 ? -27.357 41.344 27.955 1.00 20.88 ? 111 ASP A N 1 ATOM 447 C CA . ASP A 1 58 ? -27.612 40.554 29.166 1.00 20.46 ? 111 ASP A CA 1 ATOM 448 C C . ASP A 1 58 ? -29.068 40.640 29.578 1.00 15.40 ? 111 ASP A C 1 ATOM 449 O O . ASP A 1 58 ? -29.631 39.689 30.081 1.00 16.88 ? 111 ASP A O 1 ATOM 450 C CB . ASP A 1 58 ? -26.740 41.028 30.325 1.00 21.37 ? 111 ASP A CB 1 ATOM 451 C CG . ASP A 1 58 ? -25.317 40.560 30.205 1.00 21.56 ? 111 ASP A CG 1 ATOM 452 O OD1 . ASP A 1 58 ? -24.468 41.092 30.938 1.00 24.10 ? 111 ASP A OD1 1 ATOM 453 O OD2 . ASP A 1 58 ? -24.954 39.673 29.406 1.00 20.64 ? 111 ASP A OD2 1 ATOM 454 N N . GLU A 1 59 ? -29.669 41.801 29.371 1.00 16.98 ? 112 GLU A N 1 ATOM 455 C CA . GLU A 1 59 ? -31.055 42.005 29.756 1.00 19.61 ? 112 GLU A CA 1 ATOM 456 C C . GLU A 1 59 ? -31.999 41.286 28.808 1.00 19.74 ? 112 GLU A C 1 ATOM 457 O O . GLU A 1 59 ? -33.085 40.852 29.213 1.00 16.49 ? 112 GLU A O 1 ATOM 458 C CB . GLU A 1 59 ? -31.380 43.494 29.830 1.00 17.31 ? 112 GLU A CB 1 ATOM 459 C CG . GLU A 1 59 ? -30.701 44.132 31.032 1.00 20.74 ? 112 GLU A CG 1 ATOM 460 C CD . GLU A 1 59 ? -30.942 45.615 31.158 1.00 21.61 ? 112 GLU A CD 1 ATOM 461 O OE1 . GLU A 1 59 ? -31.534 46.203 30.239 1.00 24.93 ? 112 GLU A OE1 1 ATOM 462 O OE2 . GLU A 1 59 ? -30.533 46.185 32.196 1.00 27.28 ? 112 GLU A OE2 1 ATOM 463 N N . LEU A 1 60 ? -31.568 41.134 27.559 1.00 17.02 ? 113 LEU A N 1 ATOM 464 C CA . LEU A 1 60 ? -32.395 40.476 26.559 1.00 16.53 ? 113 LEU A CA 1 ATOM 465 C C . LEU A 1 60 ? -32.415 39.003 26.870 1.00 15.62 ? 113 LEU A C 1 ATOM 466 O O . LEU A 1 60 ? -33.424 38.319 26.684 1.00 16.23 ? 113 LEU A O 1 ATOM 467 C CB . LEU A 1 60 ? -31.851 40.712 25.149 1.00 15.65 ? 113 LEU A CB 1 ATOM 468 C CG . LEU A 1 60 ? -32.695 40.114 24.027 1.00 15.94 ? 113 LEU A CG 1 ATOM 469 C CD1 . LEU A 1 60 ? -33.093 41.170 23.023 1.00 18.90 ? 113 LEU A CD1 1 ATOM 470 C CD2 . LEU A 1 60 ? -31.931 39.005 23.339 1.00 15.59 ? 113 LEU A CD2 1 ATOM 471 N N . GLU A 1 61 ? -31.292 38.504 27.353 1.00 15.89 ? 114 GLU A N 1 ATOM 472 C CA . GLU A 1 61 ? -31.230 37.105 27.731 1.00 15.58 ? 114 GLU A CA 1 ATOM 473 C C . GLU A 1 61 ? -32.242 36.810 28.847 1.00 16.94 ? 114 GLU A C 1 ATOM 474 O O . GLU A 1 61 ? -32.861 35.748 28.857 1.00 15.63 ? 114 GLU A O 1 ATOM 475 C CB . GLU A 1 61 ? -29.814 36.725 28.142 1.00 15.67 ? 114 GLU A CB 1 ATOM 476 C CG . GLU A 1 61 ? -28.848 36.552 26.972 1.00 18.26 ? 114 GLU A CG 1 ATOM 477 C CD . GLU A 1 61 ? -27.381 36.658 27.384 1.00 16.60 ? 114 GLU A CD 1 ATOM 478 O OE1 . GLU A 1 61 ? -27.101 36.694 28.588 1.00 19.96 ? 114 GLU A OE1 1 ATOM 479 O OE2 . GLU A 1 61 ? -26.507 36.714 26.506 1.00 17.95 ? 114 GLU A OE2 1 ATOM 480 N N . VAL A 1 62 ? -32.411 37.732 29.793 1.00 16.43 ? 115 VAL A N 1 ATOM 481 C CA . VAL A 1 62 ? -33.326 37.467 30.904 1.00 17.10 ? 115 VAL A CA 1 ATOM 482 C C . VAL A 1 62 ? -34.732 37.260 30.319 1.00 19.60 ? 115 VAL A C 1 ATOM 483 O O . VAL A 1 62 ? -35.469 36.361 30.726 1.00 17.23 ? 115 VAL A O 1 ATOM 484 C CB . VAL A 1 62 ? -33.335 38.605 31.942 1.00 16.82 ? 115 VAL A CB 1 ATOM 485 C CG1 . VAL A 1 62 ? -34.544 38.486 32.872 1.00 18.56 ? 115 VAL A CG1 1 ATOM 486 C CG2 . VAL A 1 62 ? -32.039 38.618 32.736 1.00 17.62 ? 115 VAL A CG2 1 ATOM 487 N N . VAL A 1 63 ? -35.090 38.073 29.333 1.00 18.20 ? 116 VAL A N 1 ATOM 488 C CA . VAL A 1 63 ? -36.383 37.916 28.691 1.00 19.44 ? 116 VAL A CA 1 ATOM 489 C C . VAL A 1 63 ? -36.522 36.533 28.032 1.00 19.45 ? 116 VAL A C 1 ATOM 490 O O . VAL A 1 63 ? -37.577 35.894 28.119 1.00 19.24 ? 116 VAL A O 1 ATOM 491 C CB . VAL A 1 63 ? -36.622 39.021 27.658 1.00 21.63 ? 116 VAL A CB 1 ATOM 492 C CG1 . VAL A 1 63 ? -37.944 38.812 26.967 1.00 21.07 ? 116 VAL A CG1 1 ATOM 493 C CG2 . VAL A 1 63 ? -36.570 40.394 28.326 1.00 21.25 ? 116 VAL A CG2 1 ATOM 494 N N . LEU A 1 64 ? -35.457 36.071 27.386 1.00 17.19 ? 117 LEU A N 1 ATOM 495 C CA . LEU A 1 64 ? -35.487 34.800 26.678 1.00 17.19 ? 117 LEU A CA 1 ATOM 496 C C . LEU A 1 64 ? -35.676 33.632 27.645 1.00 18.62 ? 117 LEU A C 1 ATOM 497 O O . LEU A 1 64 ? -36.428 32.684 27.372 1.00 17.25 ? 117 LEU A O 1 ATOM 498 C CB . LEU A 1 64 ? -34.198 34.607 25.872 1.00 17.10 ? 117 LEU A CB 1 ATOM 499 C CG . LEU A 1 64 ? -33.943 35.587 24.716 1.00 16.39 ? 117 LEU A CG 1 ATOM 500 C CD1 . LEU A 1 64 ? -32.751 35.141 23.880 1.00 14.19 ? 117 LEU A CD1 1 ATOM 501 C CD2 . LEU A 1 64 ? -35.187 35.736 23.840 1.00 13.89 ? 117 LEU A CD2 1 ATOM 502 N N . LYS A 1 65 ? -34.983 33.691 28.773 1.00 17.38 ? 118 LYS A N 1 ATOM 503 C CA . LYS A 1 65 ? -35.089 32.642 29.775 1.00 17.85 ? 118 LYS A CA 1 ATOM 504 C C . LYS A 1 65 ? -36.523 32.565 30.297 1.00 20.19 ? 118 LYS A C 1 ATOM 505 O O . LYS A 1 65 ? -37.055 31.482 30.485 1.00 22.65 ? 118 LYS A O 1 ATOM 506 C CB . LYS A 1 65 ? -34.095 32.890 30.914 1.00 19.09 ? 118 LYS A CB 1 ATOM 507 C CG . LYS A 1 65 ? -34.593 32.516 32.296 1.00 19.00 ? 118 LYS A CG 1 ATOM 508 C CD . LYS A 1 65 ? -33.679 33.052 33.386 1.00 18.38 ? 118 LYS A CD 1 ATOM 509 C CE . LYS A 1 65 ? -33.534 32.024 34.528 1.00 21.35 ? 118 LYS A CE 1 ATOM 510 N NZ . LYS A 1 65 ? -34.742 31.951 35.412 1.00 22.26 ? 118 LYS A NZ 1 ATOM 511 N N . ASP A 1 66 ? -37.148 33.718 30.507 1.00 21.90 ? 119 ASP A N 1 ATOM 512 C CA . ASP A 1 66 ? -38.538 33.775 30.928 1.00 24.18 ? 119 ASP A CA 1 ATOM 513 C C . ASP A 1 66 ? -39.495 33.146 29.909 1.00 24.53 ? 119 ASP A C 1 ATOM 514 O O . ASP A 1 66 ? -40.476 32.507 30.292 1.00 22.44 ? 119 ASP A O 1 ATOM 515 C CB . ASP A 1 66 ? -38.957 35.229 31.158 1.00 28.40 ? 119 ASP A CB 1 ATOM 516 C CG . ASP A 1 66 ? -38.511 35.774 32.510 1.00 32.77 ? 119 ASP A CG 1 ATOM 517 O OD1 . ASP A 1 66 ? -37.654 35.154 33.186 1.00 34.58 ? 119 ASP A OD1 1 ATOM 518 O OD2 . ASP A 1 66 ? -38.962 36.848 32.971 1.00 37.10 ? 119 ASP A OD2 1 ATOM 519 N N . VAL A 1 67 ? -39.262 33.359 28.614 1.00 22.67 ? 120 VAL A N 1 ATOM 520 C CA . VAL A 1 67 ? -40.210 32.834 27.629 1.00 22.95 ? 120 VAL A CA 1 ATOM 521 C C . VAL A 1 67 ? -39.839 31.439 27.165 1.00 22.26 ? 120 VAL A C 1 ATOM 522 O O . VAL A 1 67 ? -40.594 30.826 26.446 1.00 26.77 ? 120 VAL A O 1 ATOM 523 C CB . VAL A 1 67 ? -40.365 33.737 26.386 1.00 23.40 ? 120 VAL A CB 1 ATOM 524 C CG1 . VAL A 1 67 ? -40.715 35.132 26.806 1.00 23.89 ? 120 VAL A CG1 1 ATOM 525 C CG2 . VAL A 1 67 ? -39.084 33.706 25.507 1.00 23.09 ? 120 VAL A CG2 1 ATOM 526 N N . LEU A 1 68 ? -38.691 30.918 27.572 1.00 22.43 ? 121 LEU A N 1 ATOM 527 C CA . LEU A 1 68 ? -38.331 29.570 27.146 1.00 22.12 ? 121 LEU A CA 1 ATOM 528 C C . LEU A 1 68 ? -38.531 28.513 28.237 1.00 23.45 ? 121 LEU A C 1 ATOM 529 O O . LEU A 1 68 ? -38.593 27.321 27.929 1.00 22.65 ? 121 LEU A O 1 ATOM 530 C CB . LEU A 1 68 ? -36.896 29.526 26.628 1.00 21.90 ? 121 LEU A CB 1 ATOM 531 C CG . LEU A 1 68 ? -36.622 30.251 25.303 1.00 19.39 ? 121 LEU A CG 1 ATOM 532 C CD1 . LEU A 1 68 ? -35.150 30.426 25.111 1.00 16.90 ? 121 LEU A CD1 1 ATOM 533 C CD2 . LEU A 1 68 ? -37.204 29.484 24.128 1.00 20.88 ? 121 LEU A CD2 1 ATOM 534 N N . GLN A 1 69 ? -38.623 28.933 29.499 1.00 22.56 ? 122 GLN A N 1 ATOM 535 C CA . GLN A 1 69 ? -38.422 27.999 30.611 1.00 22.91 ? 122 GLN A CA 1 ATOM 536 C C . GLN A 1 69 ? -39.706 27.278 31.042 1.00 24.69 ? 122 GLN A C 1 ATOM 537 O O . GLN A 1 69 ? -39.644 26.251 31.712 1.00 25.28 ? 122 GLN A O 1 ATOM 538 C CB . GLN A 1 69 ? -37.796 28.713 31.814 1.00 21.00 ? 122 GLN A CB 1 ATOM 539 C CG . GLN A 1 69 ? -38.660 29.786 32.451 1.00 21.56 ? 122 GLN A CG 1 ATOM 540 C CD . GLN A 1 69 ? -37.924 30.562 33.541 1.00 19.41 ? 122 GLN A CD 1 ATOM 541 O OE1 . GLN A 1 69 ? -36.819 30.192 33.925 1.00 20.58 ? 122 GLN A OE1 1 ATOM 542 N NE2 . GLN A 1 69 ? -38.528 31.642 34.022 1.00 18.44 ? 122 GLN A NE2 1 ATOM 543 N N . GLU A 1 70 ? -40.861 27.817 30.663 1.00 27.52 ? 123 GLU A N 1 ATOM 544 C CA . GLU A 1 70 ? -42.145 27.270 31.100 1.00 31.39 ? 123 GLU A CA 1 ATOM 545 C C . GLU A 1 70 ? -42.957 26.829 29.891 1.00 30.52 ? 123 GLU A C 1 ATOM 546 O O . GLU A 1 70 ? -43.387 27.654 29.084 1.00 27.61 ? 123 GLU A O 1 ATOM 547 C CB . GLU A 1 70 ? -42.944 28.305 31.917 1.00 35.26 ? 123 GLU A CB 1 ATOM 548 C CG . GLU A 1 70 ? -43.012 28.039 33.418 1.00 38.60 ? 123 GLU A CG 1 ATOM 549 C CD . GLU A 1 70 ? -44.026 28.926 34.144 1.00 42.86 ? 123 GLU A CD 1 ATOM 550 O OE1 . GLU A 1 70 ? -43.600 29.856 34.869 1.00 46.14 ? 123 GLU A OE1 1 ATOM 551 O OE2 . GLU A 1 70 ? -45.251 28.697 34.004 1.00 44.27 ? 123 GLU A OE2 1 ATOM 552 N N . PRO A 1 71 ? -43.169 25.523 29.782 1.00 30.18 ? 124 PRO A N 1 ATOM 553 C CA . PRO A 1 71 ? -44.123 24.953 28.827 1.00 32.75 ? 124 PRO A CA 1 ATOM 554 C C . PRO A 1 71 ? -45.483 25.634 28.890 1.00 33.54 ? 124 PRO A C 1 ATOM 555 O O . PRO A 1 71 ? -45.957 25.945 29.982 1.00 33.89 ? 124 PRO A O 1 ATOM 556 C CB . PRO A 1 71 ? -44.252 23.503 29.295 1.00 33.88 ? 124 PRO A CB 1 ATOM 557 C CG . PRO A 1 71 ? -42.951 23.200 29.969 1.00 33.10 ? 124 PRO A CG 1 ATOM 558 C CD . PRO A 1 71 ? -42.503 24.491 30.591 1.00 31.88 ? 124 PRO A CD 1 ATOM 559 N N . LYS A 1 72 ? -46.109 25.855 27.742 1.00 33.98 ? 125 LYS A N 1 ATOM 560 C CA . LYS A 1 72 ? -47.485 26.346 27.725 1.00 37.05 ? 125 LYS A CA 1 ATOM 561 C C . LYS A 1 72 ? -48.366 25.526 26.789 1.00 37.46 ? 125 LYS A C 1 ATOM 562 O O . LYS A 1 72 ? -47.960 25.186 25.677 1.00 34.79 ? 125 LYS A O 1 ATOM 563 C CB . LYS A 1 72 ? -47.531 27.825 27.339 1.00 37.24 ? 125 LYS A CB 1 ATOM 564 C CG . LYS A 1 72 ? -47.505 28.750 28.538 1.00 40.85 ? 125 LYS A CG 1 ATOM 565 C CD . LYS A 1 72 ? -48.165 30.098 28.243 1.00 43.94 ? 125 LYS A CD 1 ATOM 566 C CE . LYS A 1 72 ? -48.864 30.672 29.490 1.00 45.18 ? 125 LYS A CE 1 ATOM 567 N NZ . LYS A 1 72 ? -48.134 31.837 30.094 1.00 43.99 ? 125 LYS A NZ 1 ATOM 568 N N . THR A 1 73 ? -49.574 25.210 27.255 1.00 38.54 ? 126 THR A N 1 ATOM 569 C CA . THR A 1 73 ? -50.405 24.200 26.615 1.00 37.52 ? 126 THR A CA 1 ATOM 570 C C . THR A 1 73 ? -50.596 24.562 25.154 1.00 36.86 ? 126 THR A C 1 ATOM 571 O O . THR A 1 73 ? -50.560 23.699 24.273 1.00 34.80 ? 126 THR A O 1 ATOM 572 C CB . THR A 1 73 ? -51.772 24.103 27.308 1.00 40.26 ? 126 THR A CB 1 ATOM 573 O OG1 . THR A 1 73 ? -51.707 23.203 28.427 1.00 38.72 ? 126 THR A OG1 1 ATOM 574 C CG2 . THR A 1 73 ? -52.797 23.463 26.376 1.00 41.12 ? 126 THR A CG2 1 ATOM 575 N N . GLU A 1 74 ? -50.783 25.852 24.898 1.00 38.40 ? 127 GLU A N 1 ATOM 576 C CA . GLU A 1 74 ? -51.163 26.322 23.572 1.00 38.06 ? 127 GLU A CA 1 ATOM 577 C C . GLU A 1 74 ? -49.958 26.468 22.662 1.00 35.08 ? 127 GLU A C 1 ATOM 578 O O . GLU A 1 74 ? -50.100 26.884 21.518 1.00 34.72 ? 127 GLU A O 1 ATOM 579 C CB . GLU A 1 74 ? -51.880 27.664 23.665 1.00 40.90 ? 127 GLU A CB 1 ATOM 580 C CG . GLU A 1 74 ? -50.981 28.808 24.093 1.00 45.20 ? 127 GLU A CG 1 ATOM 581 C CD . GLU A 1 74 ? -49.887 29.112 23.084 1.00 48.48 ? 127 GLU A CD 1 ATOM 582 O OE1 . GLU A 1 74 ? -48.735 29.355 23.516 1.00 49.20 ? 127 GLU A OE1 1 ATOM 583 O OE2 . GLU A 1 74 ? -50.178 29.118 21.864 1.00 50.92 ? 127 GLU A OE2 1 ATOM 584 N N . ASP A 1 75 ? -48.774 26.134 23.169 1.00 31.02 ? 128 ASP A N 1 ATOM 585 C CA . ASP A 1 75 ? -47.542 26.333 22.412 1.00 28.70 ? 128 ASP A CA 1 ATOM 586 C C . ASP A 1 75 ? -47.565 25.537 21.117 1.00 27.49 ? 128 ASP A C 1 ATOM 587 O O . ASP A 1 75 ? -47.651 24.318 21.136 1.00 27.83 ? 128 ASP A O 1 ATOM 588 C CB . ASP A 1 75 ? -46.332 25.893 23.231 1.00 26.41 ? 128 ASP A CB 1 ATOM 589 C CG . ASP A 1 75 ? -45.877 26.943 24.205 1.00 23.47 ? 128 ASP A CG 1 ATOM 590 O OD1 . ASP A 1 75 ? -46.410 28.067 24.167 1.00 23.04 ? 128 ASP A OD1 1 ATOM 591 O OD2 . ASP A 1 75 ? -44.979 26.731 25.034 1.00 22.44 ? 128 ASP A OD2 1 ATOM 592 N N . ILE A 1 76 ? -47.459 26.211 19.984 1.00 26.54 ? 129 ILE A N 1 ATOM 593 C CA . ILE A 1 76 ? -47.259 25.482 18.740 1.00 27.27 ? 129 ILE A CA 1 ATOM 594 C C . ILE A 1 76 ? -45.935 24.705 18.733 1.00 25.91 ? 129 ILE A C 1 ATOM 595 O O . ILE A 1 76 ? -45.067 24.913 19.582 1.00 25.50 ? 129 ILE A O 1 ATOM 596 C CB . ILE A 1 76 ? -47.322 26.431 17.548 1.00 24.54 ? 129 ILE A CB 1 ATOM 597 C CG1 . ILE A 1 76 ? -46.306 27.550 17.716 1.00 23.98 ? 129 ILE A CG1 1 ATOM 598 C CG2 . ILE A 1 76 ? -48.723 27.008 17.407 1.00 25.58 ? 129 ILE A CG2 1 ATOM 599 C CD1 . ILE A 1 76 ? -45.921 28.146 16.422 1.00 22.37 ? 129 ILE A CD1 1 ATOM 600 N N . VAL A 1 77 ? -45.818 23.796 17.770 1.00 24.31 ? 130 VAL A N 1 ATOM 601 C CA . VAL A 1 77 ? -44.786 22.766 17.772 1.00 22.05 ? 130 VAL A CA 1 ATOM 602 C C . VAL A 1 77 ? -43.417 23.412 17.659 1.00 22.00 ? 130 VAL A C 1 ATOM 603 O O . VAL A 1 77 ? -42.447 22.948 18.250 1.00 25.43 ? 130 VAL A O 1 ATOM 604 C CB . VAL A 1 77 ? -45.010 21.780 16.605 1.00 17.26 ? 130 VAL A CB 1 ATOM 605 C CG1 . VAL A 1 77 ? -43.795 20.859 16.396 1.00 16.66 ? 130 VAL A CG1 1 ATOM 606 C CG2 . VAL A 1 77 ? -46.258 20.972 16.881 1.00 17.93 ? 130 VAL A CG2 1 ATOM 607 N N . ALA A 1 78 ? -43.369 24.502 16.906 1.00 20.31 ? 131 ALA A N 1 ATOM 608 C CA . ALA A 1 78 ? -42.126 25.169 16.596 1.00 21.81 ? 131 ALA A CA 1 ATOM 609 C C . ALA A 1 78 ? -41.472 25.680 17.872 1.00 22.23 ? 131 ALA A C 1 ATOM 610 O O . ALA A 1 78 ? -40.265 25.765 17.967 1.00 23.14 ? 131 ALA A O 1 ATOM 611 C CB . ALA A 1 78 ? -42.382 26.323 15.624 1.00 22.85 ? 131 ALA A CB 1 ATOM 612 N N . VAL A 1 79 ? -42.294 26.009 18.853 1.00 23.49 ? 132 VAL A N 1 ATOM 613 C CA . VAL A 1 79 ? -41.883 26.679 20.072 1.00 25.66 ? 132 VAL A CA 1 ATOM 614 C C . VAL A 1 79 ? -41.673 25.637 21.158 1.00 26.23 ? 132 VAL A C 1 ATOM 615 O O . VAL A 1 79 ? -40.760 25.762 21.987 1.00 25.90 ? 132 VAL A O 1 ATOM 616 C CB . VAL A 1 79 ? -42.949 27.696 20.513 1.00 25.52 ? 132 VAL A CB 1 ATOM 617 C CG1 . VAL A 1 79 ? -43.047 27.777 22.019 1.00 27.00 ? 132 VAL A CG1 1 ATOM 618 C CG2 . VAL A 1 79 ? -42.636 29.044 19.921 1.00 26.50 ? 132 VAL A CG2 1 ATOM 619 N N . GLN A 1 80 ? -42.486 24.586 21.118 1.00 24.32 ? 133 GLN A N 1 ATOM 620 C CA . GLN A 1 80 ? -42.192 23.370 21.871 1.00 23.31 ? 133 GLN A CA 1 ATOM 621 C C . GLN A 1 80 ? -40.795 22.838 21.571 1.00 21.80 ? 133 GLN A C 1 ATOM 622 O O . GLN A 1 80 ? -40.127 22.285 22.454 1.00 22.71 ? 133 GLN A O 1 ATOM 623 C CB . GLN A 1 80 ? -43.211 22.270 21.562 1.00 23.70 ? 133 GLN A CB 1 ATOM 624 C CG . GLN A 1 80 ? -44.655 22.624 21.853 1.00 24.09 ? 133 GLN A CG 1 ATOM 625 C CD . GLN A 1 80 ? -45.606 21.553 21.343 1.00 23.71 ? 133 GLN A CD 1 ATOM 626 O OE1 . GLN A 1 80 ? -45.331 20.366 21.492 1.00 27.79 ? 133 GLN A OE1 1 ATOM 627 N NE2 . GLN A 1 80 ? -46.712 21.967 20.731 1.00 21.93 ? 133 GLN A NE2 1 ATOM 628 N N . LYS A 1 81 ? -40.362 22.966 20.323 1.00 19.13 ? 134 LYS A N 1 ATOM 629 C CA . LYS A 1 81 ? -39.022 22.528 19.958 1.00 18.38 ? 134 LYS A CA 1 ATOM 630 C C . LYS A 1 81 ? -37.992 23.437 20.610 1.00 16.48 ? 134 LYS A C 1 ATOM 631 O O . LYS A 1 81 ? -37.024 22.967 21.190 1.00 20.83 ? 134 LYS A O 1 ATOM 632 C CB . LYS A 1 81 ? -38.838 22.510 18.435 1.00 18.48 ? 134 LYS A CB 1 ATOM 633 C CG . LYS A 1 81 ? -39.935 21.735 17.678 1.00 21.97 ? 134 LYS A CG 1 ATOM 634 C CD . LYS A 1 81 ? -39.346 20.942 16.507 1.00 22.32 ? 134 LYS A CD 1 ATOM 635 C CE . LYS A 1 81 ? -40.328 19.923 15.935 1.00 22.75 ? 134 LYS A CE 1 ATOM 636 N NZ . LYS A 1 81 ? -40.611 20.168 14.486 1.00 20.53 ? 134 LYS A NZ 1 ATOM 637 N N . ALA A 1 82 ? -38.215 24.741 20.528 1.00 16.97 ? 135 ALA A N 1 ATOM 638 C CA . ALA A 1 82 ? -37.272 25.705 21.076 1.00 16.43 ? 135 ALA A CA 1 ATOM 639 C C . ALA A 1 82 ? -37.102 25.413 22.562 1.00 16.53 ? 135 ALA A C 1 ATOM 640 O O . ALA A 1 82 ? -35.983 25.268 23.057 1.00 19.77 ? 135 ALA A O 1 ATOM 641 C CB . ALA A 1 82 ? -37.780 27.132 20.850 1.00 15.66 ? 135 ALA A CB 1 ATOM 642 N N . LYS A 1 83 ? -38.228 25.283 23.262 1.00 16.59 ? 136 LYS A N 1 ATOM 643 C CA . LYS A 1 83 ? -38.217 25.086 24.698 1.00 17.05 ? 136 LYS A CA 1 ATOM 644 C C . LYS A 1 83 ? -37.587 23.729 25.020 1.00 19.67 ? 136 LYS A C 1 ATOM 645 O O . LYS A 1 83 ? -36.760 23.605 25.926 1.00 19.77 ? 136 LYS A O 1 ATOM 646 C CB . LYS A 1 83 ? -39.644 25.188 25.257 1.00 16.50 ? 136 LYS A CB 1 ATOM 647 C CG . LYS A 1 83 ? -40.287 26.552 25.027 1.00 15.89 ? 136 LYS A CG 1 ATOM 648 C CD . LYS A 1 83 ? -41.484 26.811 25.938 1.00 14.57 ? 136 LYS A CD 1 ATOM 649 C CE . LYS A 1 83 ? -42.105 28.151 25.611 1.00 12.35 ? 136 LYS A CE 1 ATOM 650 N NZ . LYS A 1 83 ? -43.420 28.326 26.260 1.00 11.61 ? 136 LYS A NZ 1 ATOM 651 N N . ALA A 1 84 ? -37.951 22.705 24.265 1.00 19.12 ? 137 ALA A N 1 ATOM 652 C CA . ALA A 1 84 ? -37.345 21.398 24.494 1.00 20.60 ? 137 ALA A CA 1 ATOM 653 C C . ALA A 1 84 ? -35.820 21.450 24.296 1.00 20.10 ? 137 ALA A C 1 ATOM 654 O O . ALA A 1 84 ? -35.069 20.811 25.033 1.00 22.59 ? 137 ALA A O 1 ATOM 655 C CB . ALA A 1 84 ? -37.984 20.341 23.591 1.00 21.31 ? 137 ALA A CB 1 ATOM 656 N N . LEU A 1 85 ? -35.371 22.211 23.303 1.00 20.14 ? 138 LEU A N 1 ATOM 657 C CA . LEU A 1 85 ? -33.944 22.408 23.059 1.00 20.27 ? 138 LEU A CA 1 ATOM 658 C C . LEU A 1 85 ? -33.291 23.151 24.215 1.00 17.89 ? 138 LEU A C 1 ATOM 659 O O . LEU A 1 85 ? -32.215 22.796 24.671 1.00 13.36 ? 138 LEU A O 1 ATOM 660 C CB . LEU A 1 85 ? -33.741 23.227 21.781 1.00 21.22 ? 138 LEU A CB 1 ATOM 661 C CG . LEU A 1 85 ? -32.304 23.444 21.286 1.00 22.49 ? 138 LEU A CG 1 ATOM 662 C CD1 . LEU A 1 85 ? -31.562 22.128 21.088 1.00 24.34 ? 138 LEU A CD1 1 ATOM 663 C CD2 . LEU A 1 85 ? -32.311 24.214 19.977 1.00 21.89 ? 138 LEU A CD2 1 ATOM 664 N N . TYR A 1 86 ? -33.955 24.213 24.652 1.00 18.82 ? 139 TYR A N 1 ATOM 665 C CA . TYR A 1 86 ? -33.607 24.893 25.883 1.00 17.72 ? 139 TYR A CA 1 ATOM 666 C C . TYR A 1 86 ? -33.448 23.919 27.048 1.00 16.68 ? 139 TYR A C 1 ATOM 667 O O . TYR A 1 86 ? -32.405 23.920 27.715 1.00 17.92 ? 139 TYR A O 1 ATOM 668 C CB . TYR A 1 86 ? -34.666 25.935 26.228 1.00 17.54 ? 139 TYR A CB 1 ATOM 669 C CG . TYR A 1 86 ? -34.282 26.730 27.445 1.00 17.32 ? 139 TYR A CG 1 ATOM 670 C CD1 . TYR A 1 86 ? -33.228 27.630 27.388 1.00 17.30 ? 139 TYR A CD1 1 ATOM 671 C CD2 . TYR A 1 86 ? -34.943 26.562 28.652 1.00 13.01 ? 139 TYR A CD2 1 ATOM 672 C CE1 . TYR A 1 86 ? -32.861 28.357 28.486 1.00 18.16 ? 139 TYR A CE1 1 ATOM 673 C CE2 . TYR A 1 86 ? -34.578 27.274 29.748 1.00 16.78 ? 139 TYR A CE2 1 ATOM 674 C CZ . TYR A 1 86 ? -33.528 28.172 29.665 1.00 18.95 ? 139 TYR A CZ 1 ATOM 675 O OH . TYR A 1 86 ? -33.144 28.908 30.761 1.00 23.06 ? 139 TYR A OH 1 ATOM 676 N N . ARG A 1 87 ? -34.465 23.087 27.278 1.00 15.63 ? 140 ARG A N 1 ATOM 677 C CA . ARG A 1 87 ? -34.448 22.152 28.409 1.00 19.40 ? 140 ARG A CA 1 ATOM 678 C C . ARG A 1 87 ? -33.326 21.141 28.272 1.00 18.93 ? 140 ARG A C 1 ATOM 679 O O . ARG A 1 87 ? -32.693 20.788 29.255 1.00 17.91 ? 140 ARG A O 1 ATOM 680 C CB . ARG A 1 87 ? -35.783 21.410 28.554 1.00 20.70 ? 140 ARG A CB 1 ATOM 681 C CG . ARG A 1 87 ? -36.903 22.272 29.116 1.00 22.32 ? 140 ARG A CG 1 ATOM 682 C CD . ARG A 1 87 ? -38.153 21.511 29.535 1.00 22.23 ? 140 ARG A CD 1 ATOM 683 N NE . ARG A 1 87 ? -38.609 20.548 28.533 1.00 25.11 ? 140 ARG A NE 1 ATOM 684 C CZ . ARG A 1 87 ? -39.533 20.805 27.620 1.00 28.45 ? 140 ARG A CZ 1 ATOM 685 N NH1 . ARG A 1 87 ? -40.092 22.009 27.556 1.00 28.58 ? 140 ARG A NH1 1 ATOM 686 N NH2 . ARG A 1 87 ? -39.896 19.864 26.761 1.00 28.54 ? 140 ARG A NH2 1 ATOM 687 N N . SER A 1 88 ? -33.083 20.658 27.055 1.00 21.73 ? 141 SER A N 1 ATOM 688 C CA . SER A 1 88 ? -32.009 19.692 26.851 1.00 20.02 ? 141 SER A CA 1 ATOM 689 C C . SER A 1 88 ? -30.671 20.362 27.098 1.00 20.99 ? 141 SER A C 1 ATOM 690 O O . SER A 1 88 ? -29.683 19.699 27.423 1.00 19.57 ? 141 SER A O 1 ATOM 691 C CB . SER A 1 88 ? -32.049 19.102 25.441 1.00 20.11 ? 141 SER A CB 1 ATOM 692 O OG . SER A 1 88 ? -31.152 19.763 24.573 1.00 16.83 ? 141 SER A OG 1 ATOM 693 N N . CYS A 1 89 ? -30.649 21.682 26.947 1.00 22.24 ? 142 CYS A N 1 ATOM 694 C CA . CYS A 1 89 ? -29.402 22.429 27.010 1.00 21.81 ? 142 CYS A CA 1 ATOM 695 C C . CYS A 1 89 ? -29.026 22.773 28.448 1.00 20.38 ? 142 CYS A C 1 ATOM 696 O O . CYS A 1 89 ? -27.865 22.700 28.802 1.00 19.08 ? 142 CYS A O 1 ATOM 697 C CB . CYS A 1 89 ? -29.475 23.702 26.172 1.00 19.32 ? 142 CYS A CB 1 ATOM 698 S SG . CYS A 1 89 ? -27.914 24.609 26.152 1.00 20.03 ? 142 CYS A SG 1 ATOM 699 N N . ILE A 1 90 ? -30.003 23.103 29.287 1.00 19.22 ? 143 ILE A N 1 ATOM 700 C CA . ILE A 1 90 ? -29.695 23.426 30.682 1.00 20.67 ? 143 ILE A CA 1 ATOM 701 C C . ILE A 1 90 ? -29.613 22.232 31.637 1.00 19.70 ? 143 ILE A C 1 ATOM 702 O O . ILE A 1 90 ? -29.280 22.410 32.796 1.00 20.40 ? 143 ILE A O 1 ATOM 703 C CB . ILE A 1 90 ? -30.701 24.429 31.246 1.00 18.90 ? 143 ILE A CB 1 ATOM 704 C CG1 . ILE A 1 90 ? -31.998 23.696 31.593 1.00 22.77 ? 143 ILE A CG1 1 ATOM 705 C CG2 . ILE A 1 90 ? -30.924 25.565 30.261 1.00 21.84 ? 143 ILE A CG2 1 ATOM 706 C CD1 . ILE A 1 90 ? -33.201 24.582 31.708 1.00 23.14 ? 143 ILE A CD1 1 ATOM 707 N N . ASN A 1 91 ? -29.896 21.020 31.175 1.00 20.75 ? 144 ASN A N 1 ATOM 708 C CA . ASN A 1 91 ? -29.722 19.840 32.036 1.00 22.96 ? 144 ASN A CA 1 ATOM 709 C C . ASN A 1 91 ? -28.277 19.327 32.072 1.00 21.84 ? 144 ASN A C 1 ATOM 710 O O . ASN A 1 91 ? -27.884 18.534 31.239 1.00 23.57 ? 144 ASN A O 1 ATOM 711 C CB . ASN A 1 91 ? -30.657 18.702 31.588 1.00 25.40 ? 144 ASN A CB 1 ATOM 712 C CG . ASN A 1 91 ? -30.916 17.666 32.700 1.00 29.80 ? 144 ASN A CG 1 ATOM 713 O OD1 . ASN A 1 91 ? -30.015 17.305 33.462 1.00 28.80 ? 144 ASN A OD1 1 ATOM 714 N ND2 . ASN A 1 91 ? -32.157 17.194 32.786 1.00 34.97 ? 144 ASN A ND2 1 ATOM 715 N N . GLU A 1 92 ? -27.494 19.759 33.052 1.00 25.97 ? 145 GLU A N 1 ATOM 716 C CA . GLU A 1 92 ? -26.075 19.430 33.079 1.00 28.76 ? 145 GLU A CA 1 ATOM 717 C C . GLU A 1 92 ? -25.830 18.003 33.587 1.00 30.14 ? 145 GLU A C 1 ATOM 718 O O . GLU A 1 92 ? -24.837 17.366 33.221 1.00 27.94 ? 145 GLU A O 1 ATOM 719 C CB . GLU A 1 92 ? -25.298 20.445 33.926 1.00 31.86 ? 145 GLU A CB 1 ATOM 720 C CG . GLU A 1 92 ? -25.369 21.871 33.391 1.00 35.63 ? 145 GLU A CG 1 ATOM 721 C CD . GLU A 1 92 ? -24.375 22.819 34.049 1.00 40.33 ? 145 GLU A CD 1 ATOM 722 O OE1 . GLU A 1 92 ? -24.564 24.049 33.924 1.00 42.40 ? 145 GLU A OE1 1 ATOM 723 O OE2 . GLU A 1 92 ? -23.405 22.344 34.689 1.00 41.93 ? 145 GLU A OE2 1 ATOM 724 N N . SER A 1 93 ? -26.722 17.494 34.432 1.00 29.32 ? 146 SER A N 1 ATOM 725 C CA . SER A 1 93 ? -26.493 16.179 35.002 1.00 29.45 ? 146 SER A CA 1 ATOM 726 C C . SER A 1 93 ? -26.655 15.121 33.904 1.00 29.93 ? 146 SER A C 1 ATOM 727 O O . SER A 1 93 ? -25.802 14.255 33.733 1.00 30.83 ? 146 SER A O 1 ATOM 728 C CB . SER A 1 93 ? -27.409 15.908 36.202 1.00 31.21 ? 146 SER A CB 1 ATOM 729 O OG . SER A 1 93 ? -28.737 16.342 35.982 1.00 31.92 ? 146 SER A OG 1 ATOM 730 N N . ALA A 1 94 ? -27.723 15.225 33.130 1.00 29.29 ? 147 ALA A N 1 ATOM 731 C CA . ALA A 1 94 ? -27.835 14.452 31.897 1.00 30.54 ? 147 ALA A CA 1 ATOM 732 C C . ALA A 1 94 ? -26.554 14.507 31.057 1.00 29.53 ? 147 ALA A C 1 ATOM 733 O O . ALA A 1 94 ? -26.050 13.473 30.623 1.00 32.63 ? 147 ALA A O 1 ATOM 734 C CB . ALA A 1 94 ? -29.038 14.922 31.083 1.00 30.01 ? 147 ALA A CB 1 ATOM 735 N N . ILE A 1 95 ? -26.023 15.705 30.838 1.00 27.92 ? 148 ILE A N 1 ATOM 736 C CA . ILE A 1 95 ? -24.834 15.867 30.003 1.00 25.15 ? 148 ILE A CA 1 ATOM 737 C C . ILE A 1 95 ? -23.573 15.333 30.684 1.00 26.04 ? 148 ILE A C 1 ATOM 738 O O . ILE A 1 95 ? -22.720 14.702 30.043 1.00 26.08 ? 148 ILE A O 1 ATOM 739 C CB . ILE A 1 95 ? -24.635 17.362 29.625 1.00 23.50 ? 148 ILE A CB 1 ATOM 740 C CG1 . ILE A 1 95 ? -25.637 17.777 28.543 1.00 22.24 ? 148 ILE A CG1 1 ATOM 741 C CG2 . ILE A 1 95 ? -23.221 17.596 29.141 1.00 21.14 ? 148 ILE A CG2 1 ATOM 742 C CD1 . ILE A 1 95 ? -25.930 19.258 28.512 1.00 20.80 ? 148 ILE A CD1 1 ATOM 743 N N . ASP A 1 96 ? -23.443 15.593 31.979 1.00 24.57 ? 149 ASP A N 1 ATOM 744 C CA . ASP A 1 96 ? -22.278 15.132 32.718 1.00 25.51 ? 149 ASP A CA 1 ATOM 745 C C . ASP A 1 96 ? -22.231 13.598 32.785 1.00 26.07 ? 149 ASP A C 1 ATOM 746 O O . ASP A 1 96 ? -21.162 12.998 32.766 1.00 27.10 ? 149 ASP A O 1 ATOM 747 C CB . ASP A 1 96 ? -22.270 15.743 34.125 1.00 26.73 ? 149 ASP A CB 1 ATOM 748 C CG . ASP A 1 96 ? -21.611 17.105 34.159 1.00 26.34 ? 149 ASP A CG 1 ATOM 749 O OD1 . ASP A 1 96 ? -21.826 17.865 35.122 1.00 30.74 ? 149 ASP A OD1 1 ATOM 750 O OD2 . ASP A 1 96 ? -20.864 17.510 33.257 1.00 28.79 ? 149 ASP A OD2 1 ATOM 751 N N . SER A 1 97 ? -23.393 12.961 32.837 1.00 28.71 ? 150 SER A N 1 ATOM 752 C CA . SER A 1 97 ? -23.447 11.506 32.905 1.00 31.42 ? 150 SER A CA 1 ATOM 753 C C . SER A 1 97 ? -22.980 10.834 31.610 1.00 32.56 ? 150 SER A C 1 ATOM 754 O O . SER A 1 97 ? -22.631 9.653 31.607 1.00 34.14 ? 150 SER A O 1 ATOM 755 C CB . SER A 1 97 ? -24.866 11.041 33.257 1.00 33.05 ? 150 SER A CB 1 ATOM 756 O OG . SER A 1 97 ? -25.808 11.475 32.292 1.00 35.18 ? 150 SER A OG 1 ATOM 757 N N . ARG A 1 98 ? -22.972 11.571 30.505 1.00 33.30 ? 151 ARG A N 1 ATOM 758 C CA . ARG A 1 98 ? -22.598 10.975 29.227 1.00 31.61 ? 151 ARG A CA 1 ATOM 759 C C . ARG A 1 98 ? -21.100 11.128 28.962 1.00 32.12 ? 151 ARG A C 1 ATOM 760 O O . ARG A 1 98 ? -20.566 10.595 27.990 1.00 32.91 ? 151 ARG A O 1 ATOM 761 C CB . ARG A 1 98 ? -23.436 11.569 28.100 1.00 33.74 ? 151 ARG A CB 1 ATOM 762 C CG . ARG A 1 98 ? -24.856 11.021 28.066 1.00 35.55 ? 151 ARG A CG 1 ATOM 763 C CD . ARG A 1 98 ? -25.870 11.916 27.383 1.00 39.01 ? 151 ARG A CD 1 ATOM 764 N NE . ARG A 1 98 ? -25.796 11.803 25.931 1.00 44.41 ? 151 ARG A NE 1 ATOM 765 C CZ . ARG A 1 98 ? -26.014 10.681 25.246 1.00 47.37 ? 151 ARG A CZ 1 ATOM 766 N NH1 . ARG A 1 98 ? -26.325 9.558 25.880 1.00 49.08 ? 151 ARG A NH1 1 ATOM 767 N NH2 . ARG A 1 98 ? -25.917 10.679 23.921 1.00 47.63 ? 151 ARG A NH2 1 ATOM 768 N N . GLY A 1 99 ? -20.416 11.837 29.854 1.00 33.02 ? 152 GLY A N 1 ATOM 769 C CA . GLY A 1 99 ? -18.994 12.079 29.700 1.00 31.62 ? 152 GLY A CA 1 ATOM 770 C C . GLY A 1 99 ? -18.673 12.636 28.329 1.00 31.55 ? 152 GLY A C 1 ATOM 771 O O . GLY A 1 99 ? -19.225 13.658 27.929 1.00 30.26 ? 152 GLY A O 1 ATOM 772 N N . GLY A 1 100 ? -17.776 11.958 27.617 1.00 32.99 ? 153 GLY A N 1 ATOM 773 C CA . GLY A 1 100 ? -17.388 12.340 26.272 1.00 32.99 ? 153 GLY A CA 1 ATOM 774 C C . GLY A 1 100 ? -17.980 11.398 25.242 1.00 34.27 ? 153 GLY A C 1 ATOM 775 O O . GLY A 1 100 ? -17.778 11.563 24.029 1.00 33.58 ? 153 GLY A O 1 ATOM 776 N N . GLU A 1 101 ? -18.735 10.417 25.729 1.00 34.03 ? 154 GLU A N 1 ATOM 777 C CA . GLU A 1 101 ? -19.185 9.314 24.891 1.00 35.07 ? 154 GLU A CA 1 ATOM 778 C C . GLU A 1 101 ? -19.762 9.846 23.590 1.00 32.18 ? 154 GLU A C 1 ATOM 779 O O . GLU A 1 101 ? -19.408 9.379 22.516 1.00 31.64 ? 154 GLU A O 1 ATOM 780 C CB . GLU A 1 101 ? -20.213 8.460 25.642 1.00 39.60 ? 154 GLU A CB 1 ATOM 781 C CG . GLU A 1 101 ? -21.286 7.822 24.765 1.00 44.51 ? 154 GLU A CG 1 ATOM 782 C CD . GLU A 1 101 ? -20.781 6.632 23.963 1.00 47.32 ? 154 GLU A CD 1 ATOM 783 O OE1 . GLU A 1 101 ? -21.337 6.380 22.876 1.00 50.47 ? 154 GLU A OE1 1 ATOM 784 O OE2 . GLU A 1 101 ? -19.830 5.947 24.411 1.00 51.40 ? 154 GLU A OE2 1 ATOM 785 N N . PRO A 1 102 ? -20.636 10.842 23.682 1.00 31.23 ? 155 PRO A N 1 ATOM 786 C CA . PRO A 1 102 ? -21.274 11.420 22.495 1.00 31.99 ? 155 PRO A CA 1 ATOM 787 C C . PRO A 1 102 ? -20.268 11.898 21.440 1.00 34.13 ? 155 PRO A C 1 ATOM 788 O O . PRO A 1 102 ? -20.600 11.928 20.256 1.00 35.73 ? 155 PRO A O 1 ATOM 789 C CB . PRO A 1 102 ? -22.071 12.600 23.059 1.00 31.44 ? 155 PRO A CB 1 ATOM 790 C CG . PRO A 1 102 ? -22.271 12.294 24.490 1.00 31.66 ? 155 PRO A CG 1 ATOM 791 C CD . PRO A 1 102 ? -21.084 11.490 24.925 1.00 32.52 ? 155 PRO A CD 1 ATOM 792 N N . LEU A 1 103 ? -19.059 12.256 21.862 1.00 35.02 ? 156 LEU A N 1 ATOM 793 C CA . LEU A 1 103 ? -18.001 12.609 20.923 1.00 34.19 ? 156 LEU A CA 1 ATOM 794 C C . LEU A 1 103 ? -17.341 11.359 20.360 1.00 32.78 ? 156 LEU A C 1 ATOM 795 O O . LEU A 1 103 ? -17.077 11.280 19.164 1.00 34.03 ? 156 LEU A O 1 ATOM 796 C CB . LEU A 1 103 ? -16.951 13.501 21.599 1.00 34.58 ? 156 LEU A CB 1 ATOM 797 C CG . LEU A 1 103 ? -16.172 14.495 20.721 1.00 34.41 ? 156 LEU A CG 1 ATOM 798 C CD1 . LEU A 1 103 ? -14.857 13.925 20.251 1.00 34.54 ? 156 LEU A CD1 1 ATOM 799 C CD2 . LEU A 1 103 ? -16.983 14.958 19.524 1.00 35.44 ? 156 LEU A CD2 1 ATOM 800 N N . LEU A 1 104 ? -17.080 10.378 21.217 1.00 33.40 ? 157 LEU A N 1 ATOM 801 C CA . LEU A 1 104 ? -16.481 9.123 20.770 1.00 33.58 ? 157 LEU A CA 1 ATOM 802 C C . LEU A 1 104 ? -17.359 8.438 19.717 1.00 36.98 ? 157 LEU A C 1 ATOM 803 O O . LEU A 1 104 ? -16.846 7.896 18.734 1.00 37.50 ? 157 LEU A O 1 ATOM 804 C CB . LEU A 1 104 ? -16.239 8.176 21.947 1.00 32.21 ? 157 LEU A CB 1 ATOM 805 C CG . LEU A 1 104 ? -15.514 8.742 23.171 1.00 31.56 ? 157 LEU A CG 1 ATOM 806 C CD1 . LEU A 1 104 ? -15.698 7.826 24.384 1.00 31.24 ? 157 LEU A CD1 1 ATOM 807 C CD2 . LEU A 1 104 ? -14.049 8.940 22.884 1.00 31.71 ? 157 LEU A CD2 1 ATOM 808 N N . LYS A 1 105 ? -18.677 8.472 19.914 1.00 38.70 ? 158 LYS A N 1 ATOM 809 C CA . LYS A 1 105 ? -19.612 7.949 18.919 1.00 39.72 ? 158 LYS A CA 1 ATOM 810 C C . LYS A 1 105 ? -19.369 8.644 17.589 1.00 39.55 ? 158 LYS A C 1 ATOM 811 O O . LYS A 1 105 ? -19.706 8.124 16.525 1.00 43.31 ? 158 LYS A O 1 ATOM 812 C CB . LYS A 1 105 ? -21.062 8.177 19.355 1.00 41.09 ? 158 LYS A CB 1 ATOM 813 C CG . LYS A 1 105 ? -21.726 6.969 20.002 1.00 42.61 ? 158 LYS A CG 1 ATOM 814 C CD . LYS A 1 105 ? -22.831 7.391 20.972 1.00 42.88 ? 158 LYS A CD 1 ATOM 815 C CE . LYS A 1 105 ? -24.209 6.991 20.466 1.00 43.92 ? 158 LYS A CE 1 ATOM 816 N NZ . LYS A 1 105 ? -25.188 6.798 21.583 1.00 43.59 ? 158 LYS A NZ 1 ATOM 817 N N . LEU A 1 106 ? -18.796 9.836 17.665 1.00 36.93 ? 159 LEU A N 1 ATOM 818 C CA . LEU A 1 106 ? -18.839 10.778 16.562 1.00 34.86 ? 159 LEU A CA 1 ATOM 819 C C . LEU A 1 106 ? -17.535 10.686 15.772 1.00 32.69 ? 159 LEU A C 1 ATOM 820 O O . LEU A 1 106 ? -17.508 10.816 14.551 1.00 31.29 ? 159 LEU A O 1 ATOM 821 C CB . LEU A 1 106 ? -19.042 12.192 17.109 1.00 35.69 ? 159 LEU A CB 1 ATOM 822 C CG . LEU A 1 106 ? -19.074 13.315 16.079 1.00 35.76 ? 159 LEU A CG 1 ATOM 823 C CD1 . LEU A 1 106 ? -19.205 12.725 14.691 1.00 37.78 ? 159 LEU A CD1 1 ATOM 824 C CD2 . LEU A 1 106 ? -20.215 14.293 16.370 1.00 35.79 ? 159 LEU A CD2 1 ATOM 825 N N . LEU A 1 107 ? -16.448 10.459 16.489 1.00 33.91 ? 160 LEU A N 1 ATOM 826 C CA . LEU A 1 107 ? -15.124 10.482 15.888 1.00 35.40 ? 160 LEU A CA 1 ATOM 827 C C . LEU A 1 107 ? -14.997 9.631 14.620 1.00 36.50 ? 160 LEU A C 1 ATOM 828 O O . LEU A 1 107 ? -14.515 10.109 13.596 1.00 38.57 ? 160 LEU A O 1 ATOM 829 C CB . LEU A 1 107 ? -14.089 10.071 16.922 1.00 34.50 ? 160 LEU A CB 1 ATOM 830 C CG . LEU A 1 107 ? -13.342 11.296 17.444 1.00 35.51 ? 160 LEU A CG 1 ATOM 831 C CD1 . LEU A 1 107 ? -13.847 12.551 16.747 1.00 35.35 ? 160 LEU A CD1 1 ATOM 832 C CD2 . LEU A 1 107 ? -13.482 11.430 18.942 1.00 35.74 ? 160 LEU A CD2 1 ATOM 833 N N . PRO A 1 108 ? -15.423 8.376 14.671 1.00 38.22 ? 161 PRO A N 1 ATOM 834 C CA . PRO A 1 108 ? -15.175 7.462 13.552 1.00 38.34 ? 161 PRO A CA 1 ATOM 835 C C . PRO A 1 108 ? -15.665 8.079 12.251 1.00 38.97 ? 161 PRO A C 1 ATOM 836 O O . PRO A 1 108 ? -15.186 7.745 11.170 1.00 41.71 ? 161 PRO A O 1 ATOM 837 C CB . PRO A 1 108 ? -15.996 6.218 13.914 1.00 38.19 ? 161 PRO A CB 1 ATOM 838 C CG . PRO A 1 108 ? -16.152 6.274 15.391 1.00 38.17 ? 161 PRO A CG 1 ATOM 839 C CD . PRO A 1 108 ? -16.173 7.735 15.764 1.00 38.08 ? 161 PRO A CD 1 ATOM 840 N N . ASP A 1 109 ? -16.619 8.991 12.367 1.00 38.98 ? 162 ASP A N 1 ATOM 841 C CA . ASP A 1 109 ? -17.413 9.407 11.225 1.00 38.22 ? 162 ASP A CA 1 ATOM 842 C C . ASP A 1 109 ? -16.879 10.690 10.611 1.00 37.66 ? 162 ASP A C 1 ATOM 843 O O . ASP A 1 109 ? -17.434 11.186 9.631 1.00 37.65 ? 162 ASP A O 1 ATOM 844 C CB . ASP A 1 109 ? -18.866 9.620 11.648 1.00 39.78 ? 162 ASP A CB 1 ATOM 845 C CG . ASP A 1 109 ? -19.760 9.986 10.485 1.00 40.02 ? 162 ASP A CG 1 ATOM 846 O OD1 . ASP A 1 109 ? -20.521 10.972 10.596 1.00 39.69 ? 162 ASP A OD1 1 ATOM 847 O OD2 . ASP A 1 109 ? -19.769 9.338 9.419 1.00 42.13 ? 162 ASP A OD2 1 ATOM 848 N N . ILE A 1 110 ? -15.804 11.229 11.182 1.00 37.18 ? 163 ILE A N 1 ATOM 849 C CA . ILE A 1 110 ? -15.032 12.273 10.506 1.00 34.20 ? 163 ILE A CA 1 ATOM 850 C C . ILE A 1 110 ? -13.611 11.790 10.241 1.00 34.55 ? 163 ILE A C 1 ATOM 851 O O . ILE A 1 110 ? -12.680 12.582 10.109 1.00 32.85 ? 163 ILE A O 1 ATOM 852 C CB . ILE A 1 110 ? -15.023 13.593 11.328 1.00 31.77 ? 163 ILE A CB 1 ATOM 853 C CG1 . ILE A 1 110 ? -14.509 13.364 12.746 1.00 30.79 ? 163 ILE A CG1 1 ATOM 854 C CG2 . ILE A 1 110 ? -16.412 14.205 11.391 1.00 31.90 ? 163 ILE A CG2 1 ATOM 855 C CD1 . ILE A 1 110 ? -14.390 14.645 13.544 1.00 30.62 ? 163 ILE A CD1 1 ATOM 856 N N . TYR A 1 111 ? -13.448 10.477 10.163 1.00 36.74 ? 164 TYR A N 1 ATOM 857 C CA . TYR A 1 111 ? -12.172 9.909 9.758 1.00 38.32 ? 164 TYR A CA 1 ATOM 858 C C . TYR A 1 111 ? -11.168 9.892 10.908 1.00 37.68 ? 164 TYR A C 1 ATOM 859 O O . TYR A 1 111 ? -9.969 9.708 10.692 1.00 38.80 ? 164 TYR A O 1 ATOM 860 C CB . TYR A 1 111 ? -11.619 10.697 8.567 1.00 38.40 ? 164 TYR A CB 1 ATOM 861 C CG . TYR A 1 111 ? -12.331 10.340 7.294 1.00 39.84 ? 164 TYR A CG 1 ATOM 862 C CD1 . TYR A 1 111 ? -13.264 11.191 6.732 1.00 40.72 ? 164 TYR A CD1 1 ATOM 863 C CD2 . TYR A 1 111 ? -12.099 9.120 6.673 1.00 41.50 ? 164 TYR A CD2 1 ATOM 864 C CE1 . TYR A 1 111 ? -13.935 10.842 5.578 1.00 41.09 ? 164 TYR A CE1 1 ATOM 865 C CE2 . TYR A 1 111 ? -12.758 8.767 5.523 1.00 40.96 ? 164 TYR A CE2 1 ATOM 866 C CZ . TYR A 1 111 ? -13.677 9.626 4.977 1.00 40.68 ? 164 TYR A CZ 1 ATOM 867 O OH . TYR A 1 111 ? -14.341 9.260 3.825 1.00 41.56 ? 164 TYR A OH 1 ATOM 868 N N . GLY A 1 112 ? -11.660 10.079 12.128 1.00 34.59 ? 165 GLY A N 1 ATOM 869 C CA . GLY A 1 112 ? -10.865 9.811 13.311 1.00 34.26 ? 165 GLY A CA 1 ATOM 870 C C . GLY A 1 112 ? -10.194 11.052 13.871 1.00 32.59 ? 165 GLY A C 1 ATOM 871 O O . GLY A 1 112 ? -10.180 12.101 13.233 1.00 34.48 ? 165 GLY A O 1 ATOM 872 N N . TRP A 1 113 ? -9.632 10.927 15.069 1.00 30.14 ? 166 TRP A N 1 ATOM 873 C CA . TRP A 1 113 ? -8.563 11.816 15.502 1.00 27.47 ? 166 TRP A CA 1 ATOM 874 C C . TRP A 1 113 ? -7.301 11.028 15.813 1.00 26.10 ? 166 TRP A C 1 ATOM 875 O O . TRP A 1 113 ? -7.164 10.491 16.901 1.00 24.21 ? 166 TRP A O 1 ATOM 876 C CB . TRP A 1 113 ? -8.983 12.586 16.755 1.00 26.83 ? 166 TRP A CB 1 ATOM 877 C CG . TRP A 1 113 ? -8.172 13.833 16.997 1.00 24.33 ? 166 TRP A CG 1 ATOM 878 C CD1 . TRP A 1 113 ? -7.501 14.563 16.068 1.00 24.22 ? 166 TRP A CD1 1 ATOM 879 C CD2 . TRP A 1 113 ? -7.968 14.499 18.248 1.00 24.21 ? 166 TRP A CD2 1 ATOM 880 N NE1 . TRP A 1 113 ? -6.887 15.642 16.658 1.00 24.16 ? 166 TRP A NE1 1 ATOM 881 C CE2 . TRP A 1 113 ? -7.151 15.621 18.001 1.00 23.38 ? 166 TRP A CE2 1 ATOM 882 C CE3 . TRP A 1 113 ? -8.394 14.260 19.557 1.00 23.40 ? 166 TRP A CE3 1 ATOM 883 C CZ2 . TRP A 1 113 ? -6.755 16.496 19.007 1.00 21.96 ? 166 TRP A CZ2 1 ATOM 884 C CZ3 . TRP A 1 113 ? -8.000 15.123 20.549 1.00 24.07 ? 166 TRP A CZ3 1 ATOM 885 C CH2 . TRP A 1 113 ? -7.193 16.232 20.269 1.00 24.78 ? 166 TRP A CH2 1 ATOM 886 N N . PRO A 1 114 ? -6.371 10.980 14.869 1.00 25.42 ? 167 PRO A N 1 ATOM 887 C CA . PRO A 1 114 ? -5.240 10.051 14.954 1.00 28.13 ? 167 PRO A CA 1 ATOM 888 C C . PRO A 1 114 ? -4.579 10.075 16.332 1.00 28.51 ? 167 PRO A C 1 ATOM 889 O O . PRO A 1 114 ? -4.583 9.051 17.017 1.00 31.85 ? 167 PRO A O 1 ATOM 890 C CB . PRO A 1 114 ? -4.285 10.554 13.867 1.00 27.52 ? 167 PRO A CB 1 ATOM 891 C CG . PRO A 1 114 ? -5.186 11.224 12.864 1.00 28.91 ? 167 PRO A CG 1 ATOM 892 C CD . PRO A 1 114 ? -6.324 11.812 13.657 1.00 26.93 ? 167 PRO A CD 1 ATOM 893 N N . VAL A 1 115 ? -4.043 11.220 16.740 1.00 27.75 ? 168 VAL A N 1 ATOM 894 C CA . VAL A 1 115 ? -3.408 11.340 18.049 1.00 30.29 ? 168 VAL A CA 1 ATOM 895 C C . VAL A 1 115 ? -4.195 10.611 19.138 1.00 30.54 ? 168 VAL A C 1 ATOM 896 O O . VAL A 1 115 ? -3.632 10.213 20.144 1.00 27.96 ? 168 VAL A O 1 ATOM 897 C CB . VAL A 1 115 ? -3.157 12.818 18.440 1.00 31.53 ? 168 VAL A CB 1 ATOM 898 C CG1 . VAL A 1 115 ? -4.451 13.612 18.368 1.00 31.62 ? 168 VAL A CG1 1 ATOM 899 C CG2 . VAL A 1 115 ? -2.557 12.911 19.830 1.00 32.31 ? 168 VAL A CG2 1 ATOM 900 N N . ALA A 1 116 ? -5.487 10.400 18.926 1.00 33.77 ? 169 ALA A N 1 ATOM 901 C CA . ALA A 1 116 ? -6.317 9.785 19.955 1.00 35.32 ? 169 ALA A CA 1 ATOM 902 C C . ALA A 1 116 ? -6.840 8.428 19.492 1.00 38.24 ? 169 ALA A C 1 ATOM 903 O O . ALA A 1 116 ? -7.885 7.962 19.948 1.00 39.90 ? 169 ALA A O 1 ATOM 904 C CB . ALA A 1 116 ? -7.470 10.716 20.321 1.00 35.27 ? 169 ALA A CB 1 ATOM 905 N N . THR A 1 117 ? -6.105 7.801 18.579 1.00 40.70 ? 170 THR A N 1 ATOM 906 C CA . THR A 1 117 ? -6.496 6.508 18.025 1.00 42.25 ? 170 THR A CA 1 ATOM 907 C C . THR A 1 117 ? -5.352 5.493 18.064 1.00 42.83 ? 170 THR A C 1 ATOM 908 O O . THR A 1 117 ? -4.197 5.865 18.201 1.00 43.93 ? 170 THR A O 1 ATOM 909 C CB . THR A 1 117 ? -6.982 6.702 16.584 1.00 42.63 ? 170 THR A CB 1 ATOM 910 O OG1 . THR A 1 117 ? -7.403 8.059 16.399 1.00 42.38 ? 170 THR A OG1 1 ATOM 911 C CG2 . THR A 1 117 ? -8.231 5.898 16.322 1.00 43.12 ? 170 THR A CG2 1 ATOM 912 N N . GLU A 1 118 ? -5.695 4.210 17.957 1.00 44.80 ? 171 GLU A N 1 ATOM 913 C CA . GLU A 1 118 ? -4.767 3.167 17.517 1.00 43.22 ? 171 GLU A CA 1 ATOM 914 C C . GLU A 1 118 ? -4.782 2.981 15.997 1.00 40.81 ? 171 GLU A C 1 ATOM 915 O O . GLU A 1 118 ? -5.837 2.993 15.367 1.00 38.29 ? 171 GLU A O 1 ATOM 916 C CB . GLU A 1 118 ? -5.142 1.843 18.187 1.00 45.82 ? 171 GLU A CB 1 ATOM 917 C CG . GLU A 1 118 ? -6.643 1.576 18.230 1.00 46.90 ? 171 GLU A CG 1 ATOM 918 C CD . GLU A 1 118 ? -7.074 0.899 19.515 1.00 47.57 ? 171 GLU A CD 1 ATOM 919 O OE1 . GLU A 1 118 ? -8.295 0.854 19.792 1.00 47.89 ? 171 GLU A OE1 1 ATOM 920 O OE2 . GLU A 1 118 ? -6.186 0.411 20.249 1.00 49.38 ? 171 GLU A OE2 1 ATOM 921 N N . ASN A 1 119 ? -3.599 2.799 15.422 1.00 40.64 ? 172 ASN A N 1 ATOM 922 C CA . ASN A 1 119 ? -3.444 2.459 14.004 1.00 40.65 ? 172 ASN A CA 1 ATOM 923 C C . ASN A 1 119 ? -4.357 3.244 13.065 1.00 39.20 ? 172 ASN A C 1 ATOM 924 O O . ASN A 1 119 ? -5.037 2.667 12.214 1.00 39.76 ? 172 ASN A O 1 ATOM 925 C CB . ASN A 1 119 ? -3.637 0.949 13.790 1.00 40.74 ? 172 ASN A CB 1 ATOM 926 C CG . ASN A 1 119 ? -2.740 0.115 14.692 1.00 39.89 ? 172 ASN A CG 1 ATOM 927 O OD1 . ASN A 1 119 ? -1.513 0.139 14.564 1.00 35.67 ? 172 ASN A OD1 1 ATOM 928 N ND2 . ASN A 1 119 ? -3.351 -0.618 15.620 1.00 41.05 ? 172 ASN A ND2 1 ATOM 929 N N . TRP A 1 120 ? -4.345 4.565 13.202 1.00 37.21 ? 173 TRP A N 1 ATOM 930 C CA . TRP A 1 120 ? -5.170 5.413 12.359 1.00 36.36 ? 173 TRP A CA 1 ATOM 931 C C . TRP A 1 120 ? -4.954 5.061 10.895 1.00 36.11 ? 173 TRP A C 1 ATOM 932 O O . TRP A 1 120 ? -5.890 5.093 10.092 1.00 36.13 ? 173 TRP A O 1 ATOM 933 C CB . TRP A 1 120 ? -4.865 6.897 12.597 1.00 36.07 ? 173 TRP A CB 1 ATOM 934 C CG . TRP A 1 120 ? -5.724 7.806 11.789 1.00 33.27 ? 173 TRP A CG 1 ATOM 935 C CD1 . TRP A 1 120 ? -6.986 8.218 12.087 1.00 32.93 ? 173 TRP A CD1 1 ATOM 936 C CD2 . TRP A 1 120 ? -5.393 8.413 10.541 1.00 32.61 ? 173 TRP A CD2 1 ATOM 937 N NE1 . TRP A 1 120 ? -7.464 9.043 11.098 1.00 31.01 ? 173 TRP A NE1 1 ATOM 938 C CE2 . TRP A 1 120 ? -6.504 9.177 10.134 1.00 31.56 ? 173 TRP A CE2 1 ATOM 939 C CE3 . TRP A 1 120 ? -4.265 8.391 9.718 1.00 32.40 ? 173 TRP A CE3 1 ATOM 940 C CZ2 . TRP A 1 120 ? -6.520 9.904 8.950 1.00 32.38 ? 173 TRP A CZ2 1 ATOM 941 C CZ3 . TRP A 1 120 ? -4.285 9.113 8.542 1.00 32.02 ? 173 TRP A CZ3 1 ATOM 942 C CH2 . TRP A 1 120 ? -5.405 9.858 8.170 1.00 32.12 ? 173 TRP A CH2 1 ATOM 943 N N . GLU A 1 121 ? -3.721 4.728 10.545 1.00 36.49 ? 174 GLU A N 1 ATOM 944 C CA . GLU A 1 121 ? -3.386 4.477 9.148 1.00 38.81 ? 174 GLU A CA 1 ATOM 945 C C . GLU A 1 121 ? -4.094 3.237 8.610 1.00 39.39 ? 174 GLU A C 1 ATOM 946 O O . GLU A 1 121 ? -4.619 3.266 7.503 1.00 38.21 ? 174 GLU A O 1 ATOM 947 C CB . GLU A 1 121 ? -1.873 4.349 8.965 1.00 38.95 ? 174 GLU A CB 1 ATOM 948 C CG . GLU A 1 121 ? -1.130 5.665 9.121 1.00 39.12 ? 174 GLU A CG 1 ATOM 949 C CD . GLU A 1 121 ? -0.947 6.058 10.575 1.00 40.41 ? 174 GLU A CD 1 ATOM 950 O OE1 . GLU A 1 121 ? -1.444 5.326 11.460 1.00 39.54 ? 174 GLU A OE1 1 ATOM 951 O OE2 . GLU A 1 121 ? -0.296 7.096 10.834 1.00 41.32 ? 174 GLU A OE2 1 ATOM 952 N N . GLN A 1 122 ? -4.122 2.158 9.391 1.00 44.20 ? 175 GLN A N 1 ATOM 953 C CA . GLN A 1 122 ? -4.804 0.927 8.973 1.00 46.72 ? 175 GLN A CA 1 ATOM 954 C C . GLN A 1 122 ? -6.296 1.163 8.810 1.00 46.23 ? 175 GLN A C 1 ATOM 955 O O . GLN A 1 122 ? -6.896 0.745 7.822 1.00 49.68 ? 175 GLN A O 1 ATOM 956 C CB . GLN A 1 122 ? -4.584 -0.209 9.981 1.00 49.46 ? 175 GLN A CB 1 ATOM 957 C CG . GLN A 1 122 ? -4.604 -1.611 9.356 1.00 52.38 ? 175 GLN A CG 1 ATOM 958 C CD . GLN A 1 122 ? -5.838 -2.441 9.733 1.00 54.21 ? 175 GLN A CD 1 ATOM 959 O OE1 . GLN A 1 122 ? -6.255 -2.460 10.893 1.00 56.80 ? 175 GLN A OE1 1 ATOM 960 N NE2 . GLN A 1 122 ? -6.406 -3.142 8.754 1.00 54.87 ? 175 GLN A NE2 1 ATOM 961 N N . LYS A 1 123 ? -6.900 1.836 9.779 1.00 45.30 ? 176 LYS A N 1 ATOM 962 C CA . LYS A 1 123 ? -8.357 1.960 9.811 1.00 44.81 ? 176 LYS A CA 1 ATOM 963 C C . LYS A 1 123 ? -8.877 2.851 8.679 1.00 45.46 ? 176 LYS A C 1 ATOM 964 O O . LYS A 1 123 ? -9.816 2.483 7.978 1.00 46.64 ? 176 LYS A O 1 ATOM 965 C CB . LYS A 1 123 ? -8.807 2.492 11.170 1.00 42.87 ? 176 LYS A CB 1 ATOM 966 C CG . LYS A 1 123 ? -8.060 1.864 12.344 1.00 43.76 ? 176 LYS A CG 1 ATOM 967 C CD . LYS A 1 123 ? -8.580 2.377 13.688 1.00 45.53 ? 176 LYS A CD 1 ATOM 968 C CE . LYS A 1 123 ? -7.893 1.685 14.865 1.00 45.09 ? 176 LYS A CE 1 ATOM 969 N NZ . LYS A 1 123 ? -8.754 0.653 15.493 1.00 44.57 ? 176 LYS A NZ 1 ATOM 970 N N . TYR A 1 124 ? -8.262 4.015 8.493 1.00 45.88 ? 177 TYR A N 1 ATOM 971 C CA . TYR A 1 124 ? -8.793 5.025 7.578 1.00 47.02 ? 177 TYR A CA 1 ATOM 972 C C . TYR A 1 124 ? -7.896 5.241 6.360 1.00 48.48 ? 177 TYR A C 1 ATOM 973 O O . TYR A 1 124 ? -8.348 5.167 5.217 1.00 47.42 ? 177 TYR A O 1 ATOM 974 C CB . TYR A 1 124 ? -8.981 6.354 8.314 1.00 45.35 ? 177 TYR A CB 1 ATOM 975 C CG . TYR A 1 124 ? -9.833 6.227 9.551 1.00 44.07 ? 177 TYR A CG 1 ATOM 976 C CD1 . TYR A 1 124 ? -11.218 6.273 9.470 1.00 43.85 ? 177 TYR A CD1 1 ATOM 977 C CD2 . TYR A 1 124 ? -9.255 6.050 10.794 1.00 42.37 ? 177 TYR A CD2 1 ATOM 978 C CE1 . TYR A 1 124 ? -11.999 6.154 10.595 1.00 42.35 ? 177 TYR A CE1 1 ATOM 979 C CE2 . TYR A 1 124 ? -10.026 5.928 11.924 1.00 42.25 ? 177 TYR A CE2 1 ATOM 980 C CZ . TYR A 1 124 ? -11.399 5.982 11.821 1.00 42.81 ? 177 TYR A CZ 1 ATOM 981 O OH . TYR A 1 124 ? -12.174 5.861 12.956 1.00 41.12 ? 177 TYR A OH 1 ATOM 982 N N . GLY A 1 125 ? -6.625 5.529 6.615 1.00 53.07 ? 178 GLY A N 1 ATOM 983 C CA . GLY A 1 125 ? -5.715 5.972 5.575 1.00 54.16 ? 178 GLY A CA 1 ATOM 984 C C . GLY A 1 125 ? -5.929 5.223 4.273 1.00 55.73 ? 178 GLY A C 1 ATOM 985 O O . GLY A 1 125 ? -5.797 5.794 3.186 1.00 55.01 ? 178 GLY A O 1 ATOM 986 N N . ALA A 1 126 ? -6.270 3.941 4.376 1.00 57.04 ? 179 ALA A N 1 ATOM 987 C CA . ALA A 1 126 ? -7.059 3.299 3.337 1.00 56.44 ? 179 ALA A CA 1 ATOM 988 C C . ALA A 1 126 ? -8.026 4.329 2.790 1.00 57.44 ? 179 ALA A C 1 ATOM 989 O O . ALA A 1 126 ? -7.701 5.086 1.871 1.00 59.70 ? 179 ALA A O 1 ATOM 990 C CB . ALA A 1 126 ? -7.820 2.122 3.902 1.00 56.28 ? 179 ALA A CB 1 ATOM 991 N N . SER A 1 127 ? -9.210 4.373 3.392 1.00 56.34 ? 180 SER A N 1 ATOM 992 C CA . SER A 1 127 ? -10.340 5.073 2.812 1.00 53.79 ? 180 SER A CA 1 ATOM 993 C C . SER A 1 127 ? -9.975 6.539 2.689 1.00 53.84 ? 180 SER A C 1 ATOM 994 O O . SER A 1 127 ? -10.332 7.207 1.718 1.00 56.32 ? 180 SER A O 1 ATOM 995 C CB . SER A 1 127 ? -11.567 4.914 3.705 1.00 52.39 ? 180 SER A CB 1 ATOM 996 O OG . SER A 1 127 ? -11.178 4.812 5.060 1.00 50.39 ? 180 SER A OG 1 ATOM 997 N N . TRP A 1 128 ? -9.247 7.029 3.683 1.00 51.55 ? 181 TRP A N 1 ATOM 998 C CA . TRP A 1 128 ? -8.932 8.442 3.779 1.00 47.86 ? 181 TRP A CA 1 ATOM 999 C C . TRP A 1 128 ? -8.563 8.978 2.403 1.00 46.92 ? 181 TRP A C 1 ATOM 1000 O O . TRP A 1 128 ? -7.822 8.335 1.659 1.00 46.80 ? 181 TRP A O 1 ATOM 1001 C CB . TRP A 1 128 ? -7.777 8.632 4.760 1.00 47.27 ? 181 TRP A CB 1 ATOM 1002 C CG . TRP A 1 128 ? -7.654 10.018 5.291 1.00 46.65 ? 181 TRP A CG 1 ATOM 1003 C CD1 . TRP A 1 128 ? -8.212 10.515 6.433 1.00 45.82 ? 181 TRP A CD1 1 ATOM 1004 C CD2 . TRP A 1 128 ? -6.911 11.089 4.710 1.00 46.33 ? 181 TRP A CD2 1 ATOM 1005 N NE1 . TRP A 1 128 ? -7.864 11.834 6.593 1.00 45.69 ? 181 TRP A NE1 1 ATOM 1006 C CE2 . TRP A 1 128 ? -7.063 12.211 5.549 1.00 45.55 ? 181 TRP A CE2 1 ATOM 1007 C CE3 . TRP A 1 128 ? -6.120 11.215 3.564 1.00 45.67 ? 181 TRP A CE3 1 ATOM 1008 C CZ2 . TRP A 1 128 ? -6.460 13.434 5.278 1.00 45.18 ? 181 TRP A CZ2 1 ATOM 1009 C CZ3 . TRP A 1 128 ? -5.528 12.431 3.293 1.00 45.96 ? 181 TRP A CZ3 1 ATOM 1010 C CH2 . TRP A 1 128 ? -5.702 13.525 4.146 1.00 46.03 ? 181 TRP A CH2 1 ATOM 1011 N N . THR A 1 129 ? -9.099 10.147 2.061 1.00 46.14 ? 182 THR A N 1 ATOM 1012 C CA . THR A 1 129 ? -8.338 11.166 1.355 1.00 45.54 ? 182 THR A CA 1 ATOM 1013 C C . THR A 1 129 ? -8.897 12.552 1.660 1.00 46.33 ? 182 THR A C 1 ATOM 1014 O O . THR A 1 129 ? -9.971 12.693 2.238 1.00 45.86 ? 182 THR A O 1 ATOM 1015 C CB . THR A 1 129 ? -8.365 10.913 -0.165 1.00 47.35 ? 182 THR A CB 1 ATOM 1016 O OG1 . THR A 1 129 ? -9.660 11.226 -0.693 1.00 44.51 ? 182 THR A OG1 1 ATOM 1017 C CG2 . THR A 1 129 ? -8.194 9.432 -0.480 1.00 47.93 ? 182 THR A CG2 1 ATOM 1018 N N . ALA A 1 130 ? -8.161 13.585 1.282 1.00 45.21 ? 183 ALA A N 1 ATOM 1019 C CA . ALA A 1 130 ? -8.446 14.913 1.794 1.00 44.36 ? 183 ALA A CA 1 ATOM 1020 C C . ALA A 1 130 ? -9.723 15.473 1.179 1.00 41.99 ? 183 ALA A C 1 ATOM 1021 O O . ALA A 1 130 ? -10.487 16.175 1.843 1.00 42.24 ? 183 ALA A O 1 ATOM 1022 C CB . ALA A 1 130 ? -7.275 15.844 1.518 1.00 44.00 ? 183 ALA A CB 1 ATOM 1023 N N . GLU A 1 131 ? -9.938 15.179 -0.097 1.00 39.27 ? 184 GLU A N 1 ATOM 1024 C CA . GLU A 1 131 ? -11.247 15.345 -0.708 1.00 38.83 ? 184 GLU A CA 1 ATOM 1025 C C . GLU A 1 131 ? -12.329 14.843 0.233 1.00 37.86 ? 184 GLU A C 1 ATOM 1026 O O . GLU A 1 131 ? -13.224 15.593 0.624 1.00 35.41 ? 184 GLU A O 1 ATOM 1027 C CB . GLU A 1 131 ? -11.318 14.579 -2.026 1.00 39.02 ? 184 GLU A CB 1 ATOM 1028 C CG . GLU A 1 131 ? -10.473 15.178 -3.134 1.00 39.30 ? 184 GLU A CG 1 ATOM 1029 C CD . GLU A 1 131 ? -9.113 14.513 -3.257 1.00 41.66 ? 184 GLU A CD 1 ATOM 1030 O OE1 . GLU A 1 131 ? -8.680 13.836 -2.293 1.00 40.42 ? 184 GLU A OE1 1 ATOM 1031 O OE2 . GLU A 1 131 ? -8.472 14.673 -4.323 1.00 45.22 ? 184 GLU A OE2 1 ATOM 1032 N N . LYS A 1 132 ? -12.247 13.567 0.594 1.00 36.57 ? 185 LYS A N 1 ATOM 1033 C CA . LYS A 1 132 ? -13.360 12.897 1.260 1.00 35.59 ? 185 LYS A CA 1 ATOM 1034 C C . LYS A 1 132 ? -13.486 13.416 2.685 1.00 32.16 ? 185 LYS A C 1 ATOM 1035 O O . LYS A 1 132 ? -14.587 13.541 3.210 1.00 33.11 ? 185 LYS A O 1 ATOM 1036 C CB . LYS A 1 132 ? -13.171 11.375 1.270 1.00 37.35 ? 185 LYS A CB 1 ATOM 1037 C CG . LYS A 1 132 ? -13.604 10.695 -0.009 1.00 39.78 ? 185 LYS A CG 1 ATOM 1038 C CD . LYS A 1 132 ? -14.299 9.376 0.288 1.00 41.68 ? 185 LYS A CD 1 ATOM 1039 C CE . LYS A 1 132 ? -13.346 8.194 0.178 1.00 42.36 ? 185 LYS A CE 1 ATOM 1040 N NZ . LYS A 1 132 ? -13.025 7.608 1.508 1.00 45.14 ? 185 LYS A NZ 1 ATOM 1041 N N . ALA A 1 133 ? -12.349 13.716 3.303 1.00 31.29 ? 186 ALA A N 1 ATOM 1042 C CA . ALA A 1 133 ? -12.310 14.115 4.709 1.00 30.69 ? 186 ALA A CA 1 ATOM 1043 C C . ALA A 1 133 ? -12.696 15.581 4.913 1.00 29.01 ? 186 ALA A C 1 ATOM 1044 O O . ALA A 1 133 ? -13.455 15.907 5.819 1.00 30.40 ? 186 ALA A O 1 ATOM 1045 C CB . ALA A 1 133 ? -10.936 13.856 5.294 1.00 30.75 ? 186 ALA A CB 1 ATOM 1046 N N . ILE A 1 134 ? -12.178 16.465 4.077 1.00 27.74 ? 187 ILE A N 1 ATOM 1047 C CA . ILE A 1 134 ? -12.511 17.873 4.202 1.00 27.76 ? 187 ILE A CA 1 ATOM 1048 C C . ILE A 1 134 ? -13.985 18.043 3.922 1.00 29.53 ? 187 ILE A C 1 ATOM 1049 O O . ILE A 1 134 ? -14.675 18.845 4.562 1.00 27.83 ? 187 ILE A O 1 ATOM 1050 C CB . ILE A 1 134 ? -11.698 18.718 3.226 1.00 26.71 ? 187 ILE A CB 1 ATOM 1051 C CG1 . ILE A 1 134 ? -10.214 18.615 3.542 1.00 28.95 ? 187 ILE A CG1 1 ATOM 1052 C CG2 . ILE A 1 134 ? -12.114 20.150 3.316 1.00 25.83 ? 187 ILE A CG2 1 ATOM 1053 C CD1 . ILE A 1 134 ? -9.320 19.154 2.447 1.00 28.69 ? 187 ILE A CD1 1 ATOM 1054 N N . ALA A 1 135 ? -14.462 17.262 2.961 1.00 28.85 ? 188 ALA A N 1 ATOM 1055 C CA . ALA A 1 135 ? -15.833 17.364 2.500 1.00 27.04 ? 188 ALA A CA 1 ATOM 1056 C C . ALA A 1 135 ? -16.824 16.866 3.547 1.00 24.10 ? 188 ALA A C 1 ATOM 1057 O O . ALA A 1 135 ? -17.928 17.390 3.642 1.00 19.21 ? 188 ALA A O 1 ATOM 1058 C CB . ALA A 1 135 ? -16.005 16.595 1.203 1.00 27.73 ? 188 ALA A CB 1 ATOM 1059 N N . GLN A 1 136 ? -16.444 15.852 4.319 1.00 26.73 ? 189 GLN A N 1 ATOM 1060 C CA . GLN A 1 136 ? -17.328 15.352 5.365 1.00 29.31 ? 189 GLN A CA 1 ATOM 1061 C C . GLN A 1 136 ? -17.543 16.485 6.345 1.00 29.16 ? 189 GLN A C 1 ATOM 1062 O O . GLN A 1 136 ? -18.670 16.910 6.564 1.00 30.37 ? 189 GLN A O 1 ATOM 1063 C CB . GLN A 1 136 ? -16.723 14.164 6.107 1.00 32.04 ? 189 GLN A CB 1 ATOM 1064 C CG . GLN A 1 136 ? -17.374 12.816 5.823 1.00 35.07 ? 189 GLN A CG 1 ATOM 1065 C CD . GLN A 1 136 ? -18.880 12.821 5.959 1.00 34.61 ? 189 GLN A CD 1 ATOM 1066 O OE1 . GLN A 1 136 ? -19.571 13.453 5.169 1.00 39.55 ? 189 GLN A OE1 1 ATOM 1067 N NE2 . GLN A 1 136 ? -19.393 12.095 6.942 1.00 32.28 ? 189 GLN A NE2 1 ATOM 1068 N N . LEU A 1 137 ? -16.447 16.975 6.923 1.00 28.42 ? 190 LEU A N 1 ATOM 1069 C CA . LEU A 1 137 ? -16.524 17.983 7.965 1.00 24.93 ? 190 LEU A CA 1 ATOM 1070 C C . LEU A 1 137 ? -17.376 19.137 7.484 1.00 24.41 ? 190 LEU A C 1 ATOM 1071 O O . LEU A 1 137 ? -18.209 19.642 8.227 1.00 20.46 ? 190 LEU A O 1 ATOM 1072 C CB . LEU A 1 137 ? -15.128 18.455 8.376 1.00 24.44 ? 190 LEU A CB 1 ATOM 1073 C CG . LEU A 1 137 ? -14.442 17.516 9.375 1.00 23.22 ? 190 LEU A CG 1 ATOM 1074 C CD1 . LEU A 1 137 ? -12.958 17.854 9.573 1.00 23.15 ? 190 LEU A CD1 1 ATOM 1075 C CD2 . LEU A 1 137 ? -15.180 17.519 10.703 1.00 21.57 ? 190 LEU A CD2 1 ATOM 1076 N N . ASN A 1 138 ? -17.190 19.526 6.223 1.00 26.45 ? 191 ASN A N 1 ATOM 1077 C CA . ASN A 1 138 ? -17.873 20.690 5.662 1.00 26.13 ? 191 ASN A CA 1 ATOM 1078 C C . ASN A 1 138 ? -19.385 20.489 5.459 1.00 28.20 ? 191 ASN A C 1 ATOM 1079 O O . ASN A 1 138 ? -20.184 21.390 5.731 1.00 26.13 ? 191 ASN A O 1 ATOM 1080 C CB . ASN A 1 138 ? -17.215 21.092 4.341 1.00 25.91 ? 191 ASN A CB 1 ATOM 1081 C CG . ASN A 1 138 ? -18.076 22.034 3.519 1.00 27.39 ? 191 ASN A CG 1 ATOM 1082 O OD1 . ASN A 1 138 ? -19.246 21.760 3.279 1.00 29.27 ? 191 ASN A OD1 1 ATOM 1083 N ND2 . ASN A 1 138 ? -17.493 23.148 3.071 1.00 27.77 ? 191 ASN A ND2 1 ATOM 1084 N N . SER A 1 139 ? -19.783 19.326 4.961 1.00 28.53 ? 192 SER A N 1 ATOM 1085 C CA . SER A 1 139 ? -21.153 19.159 4.466 1.00 31.20 ? 192 SER A CA 1 ATOM 1086 C C . SER A 1 139 ? -22.052 18.574 5.545 1.00 31.31 ? 192 SER A C 1 ATOM 1087 O O . SER A 1 139 ? -23.248 18.850 5.580 1.00 32.64 ? 192 SER A O 1 ATOM 1088 C CB . SER A 1 139 ? -21.192 18.246 3.238 1.00 29.79 ? 192 SER A CB 1 ATOM 1089 O OG . SER A 1 139 ? -20.838 16.928 3.606 1.00 30.74 ? 192 SER A OG 1 ATOM 1090 N N . LYS A 1 140 ? -21.471 17.758 6.415 1.00 30.10 ? 193 LYS A N 1 ATOM 1091 C CA . LYS A 1 140 ? -22.214 17.169 7.515 1.00 32.91 ? 193 LYS A CA 1 ATOM 1092 C C . LYS A 1 140 ? -22.211 18.096 8.738 1.00 31.06 ? 193 LYS A C 1 ATOM 1093 O O . LYS A 1 140 ? -23.221 18.234 9.419 1.00 29.72 ? 193 LYS A O 1 ATOM 1094 C CB . LYS A 1 140 ? -21.625 15.800 7.886 1.00 37.19 ? 193 LYS A CB 1 ATOM 1095 C CG . LYS A 1 140 ? -22.535 14.609 7.573 1.00 41.35 ? 193 LYS A CG 1 ATOM 1096 C CD . LYS A 1 140 ? -22.001 13.315 8.209 1.00 43.70 ? 193 LYS A CD 1 ATOM 1097 C CE . LYS A 1 140 ? -23.067 12.222 8.296 1.00 44.10 ? 193 LYS A CE 1 ATOM 1098 N NZ . LYS A 1 140 ? -23.188 11.658 9.678 1.00 43.06 ? 193 LYS A NZ 1 ATOM 1099 N N . TYR A 1 141 ? -21.074 18.719 9.025 1.00 28.16 ? 194 TYR A N 1 ATOM 1100 C CA . TYR A 1 141 ? -20.912 19.422 10.297 1.00 26.95 ? 194 TYR A CA 1 ATOM 1101 C C . TYR A 1 141 ? -20.551 20.888 10.095 1.00 25.31 ? 194 TYR A C 1 ATOM 1102 O O . TYR A 1 141 ? -20.366 21.632 11.051 1.00 26.77 ? 194 TYR A O 1 ATOM 1103 C CB . TYR A 1 141 ? -19.871 18.716 11.167 1.00 25.33 ? 194 TYR A CB 1 ATOM 1104 C CG . TYR A 1 141 ? -20.176 17.251 11.370 1.00 27.07 ? 194 TYR A CG 1 ATOM 1105 C CD1 . TYR A 1 141 ? -21.164 16.845 12.258 1.00 27.30 ? 194 TYR A CD1 1 ATOM 1106 C CD2 . TYR A 1 141 ? -19.495 16.273 10.659 1.00 28.41 ? 194 TYR A CD2 1 ATOM 1107 C CE1 . TYR A 1 141 ? -21.452 15.508 12.442 1.00 27.04 ? 194 TYR A CE1 1 ATOM 1108 C CE2 . TYR A 1 141 ? -19.774 14.932 10.837 1.00 27.78 ? 194 TYR A CE2 1 ATOM 1109 C CZ . TYR A 1 141 ? -20.755 14.553 11.729 1.00 28.02 ? 194 TYR A CZ 1 ATOM 1110 O OH . TYR A 1 141 ? -21.042 13.218 11.904 1.00 24.71 ? 194 TYR A OH 1 ATOM 1111 N N . GLY A 1 142 ? -20.476 21.296 8.837 1.00 28.83 ? 195 GLY A N 1 ATOM 1112 C CA . GLY A 1 142 ? -20.285 22.691 8.489 1.00 30.02 ? 195 GLY A CA 1 ATOM 1113 C C . GLY A 1 142 ? -18.955 23.229 8.968 1.00 30.45 ? 195 GLY A C 1 ATOM 1114 O O . GLY A 1 142 ? -18.765 24.444 9.022 1.00 33.65 ? 195 GLY A O 1 ATOM 1115 N N . LYS A 1 143 ? -18.036 22.334 9.322 1.00 27.08 ? 196 LYS A N 1 ATOM 1116 C CA . LYS A 1 143 ? -16.714 22.749 9.762 1.00 26.49 ? 196 LYS A CA 1 ATOM 1117 C C . LYS A 1 143 ? -15.765 22.897 8.571 1.00 25.47 ? 196 LYS A C 1 ATOM 1118 O O . LYS A 1 143 ? -15.617 21.977 7.770 1.00 27.39 ? 196 LYS A O 1 ATOM 1119 C CB . LYS A 1 143 ? -16.146 21.738 10.754 1.00 26.57 ? 196 LYS A CB 1 ATOM 1120 C CG . LYS A 1 143 ? -15.110 22.328 11.694 1.00 25.98 ? 196 LYS A CG 1 ATOM 1121 C CD . LYS A 1 143 ? -15.555 23.692 12.192 1.00 23.97 ? 196 LYS A CD 1 ATOM 1122 C CE . LYS A 1 143 ? -14.939 24.023 13.511 1.00 22.84 ? 196 LYS A CE 1 ATOM 1123 N NZ . LYS A 1 143 ? -14.674 25.472 13.635 1.00 22.74 ? 196 LYS A NZ 1 ATOM 1124 N N . LYS A 1 144 ? -15.134 24.059 8.455 1.00 23.30 ? 197 LYS A N 1 ATOM 1125 C CA . LYS A 1 144 ? -14.420 24.425 7.231 1.00 22.71 ? 197 LYS A CA 1 ATOM 1126 C C . LYS A 1 144 ? -12.926 24.490 7.479 1.00 23.68 ? 197 LYS A C 1 ATOM 1127 O O . LYS A 1 144 ? -12.429 25.424 8.102 1.00 21.55 ? 197 LYS A O 1 ATOM 1128 C CB . LYS A 1 144 ? -14.900 25.775 6.699 1.00 22.30 ? 197 LYS A CB 1 ATOM 1129 C CG . LYS A 1 144 ? -16.413 25.869 6.520 1.00 24.56 ? 197 LYS A CG 1 ATOM 1130 C CD . LYS A 1 144 ? -16.939 24.783 5.599 1.00 24.30 ? 197 LYS A CD 1 ATOM 1131 C CE . LYS A 1 144 ? -18.465 24.836 5.468 1.00 25.43 ? 197 LYS A CE 1 ATOM 1132 N NZ . LYS A 1 144 ? -18.939 26.148 4.977 1.00 26.03 ? 197 LYS A NZ 1 ATOM 1133 N N . VAL A 1 145 ? -12.218 23.479 6.994 1.00 25.84 ? 198 VAL A N 1 ATOM 1134 C CA . VAL A 1 145 ? -10.807 23.331 7.277 1.00 27.48 ? 198 VAL A CA 1 ATOM 1135 C C . VAL A 1 145 ? -10.053 23.241 5.963 1.00 29.64 ? 198 VAL A C 1 ATOM 1136 O O . VAL A 1 145 ? -10.599 22.757 4.964 1.00 29.87 ? 198 VAL A O 1 ATOM 1137 C CB . VAL A 1 145 ? -10.536 22.085 8.128 1.00 28.93 ? 198 VAL A CB 1 ATOM 1138 C CG1 . VAL A 1 145 ? -11.293 22.181 9.430 1.00 29.38 ? 198 VAL A CG1 1 ATOM 1139 C CG2 . VAL A 1 145 ? -10.942 20.838 7.390 1.00 30.32 ? 198 VAL A CG2 1 ATOM 1140 N N . LEU A 1 146 ? -8.816 23.742 5.976 1.00 27.80 ? 199 LEU A N 1 ATOM 1141 C CA . LEU A 1 146 ? -7.897 23.682 4.841 1.00 26.39 ? 199 LEU A CA 1 ATOM 1142 C C . LEU A 1 146 ? -8.374 24.534 3.670 1.00 26.95 ? 199 LEU A C 1 ATOM 1143 O O . LEU A 1 146 ? -7.707 25.485 3.285 1.00 24.43 ? 199 LEU A O 1 ATOM 1144 C CB . LEU A 1 146 ? -7.677 22.239 4.391 1.00 28.10 ? 199 LEU A CB 1 ATOM 1145 C CG . LEU A 1 146 ? -6.952 21.320 5.383 1.00 30.78 ? 199 LEU A CG 1 ATOM 1146 C CD1 . LEU A 1 146 ? -6.437 20.083 4.663 1.00 30.85 ? 199 LEU A CD1 1 ATOM 1147 C CD2 . LEU A 1 146 ? -5.813 22.033 6.081 1.00 31.00 ? 199 LEU A CD2 1 ATOM 1148 N N . ILE A 1 147 ? -9.522 24.177 3.103 1.00 28.10 ? 200 ILE A N 1 ATOM 1149 C CA . ILE A 1 147 ? -10.136 24.947 2.033 1.00 28.70 ? 200 ILE A CA 1 ATOM 1150 C C . ILE A 1 147 ? -11.592 25.116 2.409 1.00 31.29 ? 200 ILE A C 1 ATOM 1151 O O . ILE A 1 147 ? -12.254 24.145 2.755 1.00 35.63 ? 200 ILE A O 1 ATOM 1152 C CB . ILE A 1 147 ? -10.053 24.183 0.696 1.00 30.60 ? 200 ILE A CB 1 ATOM 1153 C CG1 . ILE A 1 147 ? -8.643 23.654 0.446 1.00 29.77 ? 200 ILE A CG1 1 ATOM 1154 C CG2 . ILE A 1 147 ? -10.498 25.057 -0.459 1.00 32.25 ? 200 ILE A CG2 1 ATOM 1155 C CD1 . ILE A 1 147 ? -8.616 22.489 -0.508 1.00 29.85 ? 200 ILE A CD1 1 ATOM 1156 N N . ASN A 1 148 ? -12.095 26.339 2.345 1.00 31.66 ? 201 ASN A N 1 ATOM 1157 C CA . ASN A 1 148 ? -13.492 26.594 2.653 1.00 31.01 ? 201 ASN A CA 1 ATOM 1158 C C . ASN A 1 148 ? -14.346 26.700 1.397 1.00 30.30 ? 201 ASN A C 1 ATOM 1159 O O . ASN A 1 148 ? -14.372 27.726 0.728 1.00 33.47 ? 201 ASN A O 1 ATOM 1160 C CB . ASN A 1 148 ? -13.644 27.864 3.482 1.00 29.83 ? 201 ASN A CB 1 ATOM 1161 C CG . ASN A 1 148 ? -15.088 28.137 3.846 1.00 28.71 ? 201 ASN A CG 1 ATOM 1162 O OD1 . ASN A 1 148 ? -15.940 27.271 3.689 1.00 28.28 ? 201 ASN A OD1 1 ATOM 1163 N ND2 . ASN A 1 148 ? -15.371 29.341 4.305 1.00 26.08 ? 201 ASN A ND2 1 ATOM 1164 N N . LEU A 1 149 ? -15.056 25.633 1.084 1.00 31.90 ? 202 LEU A N 1 ATOM 1165 C CA . LEU A 1 149 ? -16.115 25.697 0.092 1.00 33.27 ? 202 LEU A CA 1 ATOM 1166 C C . LEU A 1 149 ? -17.413 26.088 0.783 1.00 32.16 ? 202 LEU A C 1 ATOM 1167 O O . LEU A 1 149 ? -17.726 25.587 1.861 1.00 32.37 ? 202 LEU A O 1 ATOM 1168 C CB . LEU A 1 149 ? -16.271 24.340 -0.593 1.00 34.50 ? 202 LEU A CB 1 ATOM 1169 C CG . LEU A 1 149 ? -16.501 24.368 -2.102 1.00 35.96 ? 202 LEU A CG 1 ATOM 1170 C CD1 . LEU A 1 149 ? -17.968 24.554 -2.411 1.00 34.81 ? 202 LEU A CD1 1 ATOM 1171 C CD2 . LEU A 1 149 ? -15.666 25.470 -2.734 1.00 37.32 ? 202 LEU A CD2 1 ATOM 1172 N N . PHE A 1 150 ? -18.154 27.004 0.172 1.00 34.10 ? 203 PHE A N 1 ATOM 1173 C CA . PHE A 1 150 ? -19.419 27.456 0.735 1.00 33.64 ? 203 PHE A CA 1 ATOM 1174 C C . PHE A 1 150 ? -20.363 27.908 -0.374 1.00 34.47 ? 203 PHE A C 1 ATOM 1175 O O . PHE A 1 150 ? -20.009 28.732 -1.210 1.00 34.56 ? 203 PHE A O 1 ATOM 1176 C CB . PHE A 1 150 ? -19.190 28.543 1.806 1.00 32.50 ? 203 PHE A CB 1 ATOM 1177 C CG . PHE A 1 150 ? -19.265 29.966 1.293 1.00 32.66 ? 203 PHE A CG 1 ATOM 1178 C CD1 . PHE A 1 150 ? -20.485 30.541 0.976 1.00 32.15 ? 203 PHE A CD1 1 ATOM 1179 C CD2 . PHE A 1 150 ? -18.118 30.749 1.183 1.00 31.94 ? 203 PHE A CD2 1 ATOM 1180 C CE1 . PHE A 1 150 ? -20.563 31.842 0.527 1.00 33.02 ? 203 PHE A CE1 1 ATOM 1181 C CE2 . PHE A 1 150 ? -18.195 32.053 0.735 1.00 32.32 ? 203 PHE A CE2 1 ATOM 1182 C CZ . PHE A 1 150 ? -19.418 32.599 0.406 1.00 33.65 ? 203 PHE A CZ 1 ATOM 1183 N N . VAL A 1 151 ? -21.565 27.340 -0.404 1.00 32.31 ? 204 VAL A N 1 ATOM 1184 C CA . VAL A 1 151 ? -22.604 27.923 -1.224 1.00 29.96 ? 204 VAL A CA 1 ATOM 1185 C C . VAL A 1 151 ? -22.949 29.274 -0.635 1.00 28.82 ? 204 VAL A C 1 ATOM 1186 O O . VAL A 1 151 ? -23.185 29.405 0.563 1.00 28.67 ? 204 VAL A O 1 ATOM 1187 C CB . VAL A 1 151 ? -23.861 27.047 -1.299 1.00 31.06 ? 204 VAL A CB 1 ATOM 1188 C CG1 . VAL A 1 151 ? -24.786 27.547 -2.394 1.00 31.63 ? 204 VAL A CG1 1 ATOM 1189 C CG2 . VAL A 1 151 ? -23.495 25.602 -1.546 1.00 30.87 ? 204 VAL A CG2 1 ATOM 1190 N N . GLY A 1 152 ? -22.947 30.291 -1.481 1.00 29.11 ? 205 GLY A N 1 ATOM 1191 C CA . GLY A 1 152 ? -23.281 31.630 -1.051 1.00 27.89 ? 205 GLY A CA 1 ATOM 1192 C C . GLY A 1 152 ? -24.025 32.353 -2.144 1.00 29.13 ? 205 GLY A C 1 ATOM 1193 O O . GLY A 1 152 ? -24.241 31.805 -3.214 1.00 31.87 ? 205 GLY A O 1 ATOM 1194 N N . THR A 1 153 ? -24.424 33.585 -1.861 1.00 30.18 ? 206 THR A N 1 ATOM 1195 C CA . THR A 1 153 ? -24.931 34.499 -2.869 1.00 28.82 ? 206 THR A CA 1 ATOM 1196 C C . THR A 1 153 ? -23.817 34.944 -3.817 1.00 30.61 ? 206 THR A C 1 ATOM 1197 O O . THR A 1 153 ? -22.638 34.939 -3.450 1.00 31.70 ? 206 THR A O 1 ATOM 1198 C CB . THR A 1 153 ? -25.531 35.722 -2.165 1.00 28.18 ? 206 THR A CB 1 ATOM 1199 O OG1 . THR A 1 153 ? -26.644 35.321 -1.358 1.00 27.21 ? 206 THR A OG1 1 ATOM 1200 C CG2 . THR A 1 153 ? -26.136 36.690 -3.155 1.00 29.88 ? 206 THR A CG2 1 ATOM 1201 N N . ASP A 1 154 ? -24.191 35.343 -5.032 1.00 29.07 ? 207 ASP A N 1 ATOM 1202 C CA . ASP A 1 154 ? -23.210 35.801 -6.014 1.00 26.92 ? 207 ASP A CA 1 ATOM 1203 C C . ASP A 1 154 ? -23.097 37.315 -6.024 1.00 23.62 ? 207 ASP A C 1 ATOM 1204 O O . ASP A 1 154 ? -24.060 38.013 -6.305 1.00 21.37 ? 207 ASP A O 1 ATOM 1205 C CB . ASP A 1 154 ? -23.577 35.316 -7.413 1.00 28.27 ? 207 ASP A CB 1 ATOM 1206 C CG . ASP A 1 154 ? -22.475 35.556 -8.407 1.00 28.54 ? 207 ASP A CG 1 ATOM 1207 O OD1 . ASP A 1 154 ? -22.339 34.734 -9.337 1.00 27.46 ? 207 ASP A OD1 1 ATOM 1208 O OD2 . ASP A 1 154 ? -21.690 36.538 -8.322 1.00 30.54 ? 207 ASP A OD2 1 ATOM 1209 N N . ASP A 1 155 ? -21.918 37.829 -5.705 1.00 23.27 ? 208 ASP A N 1 ATOM 1210 C CA . ASP A 1 155 ? -21.741 39.274 -5.597 1.00 25.74 ? 208 ASP A CA 1 ATOM 1211 C C . ASP A 1 155 ? -22.121 40.026 -6.885 1.00 27.19 ? 208 ASP A C 1 ATOM 1212 O O . ASP A 1 155 ? -22.407 41.218 -6.836 1.00 24.78 ? 208 ASP A O 1 ATOM 1213 C CB . ASP A 1 155 ? -20.301 39.613 -5.204 1.00 25.26 ? 208 ASP A CB 1 ATOM 1214 C CG . ASP A 1 155 ? -19.878 38.941 -3.911 1.00 26.27 ? 208 ASP A CG 1 ATOM 1215 O OD1 . ASP A 1 155 ? -18.680 38.622 -3.771 1.00 26.09 ? 208 ASP A OD1 1 ATOM 1216 O OD2 . ASP A 1 155 ? -20.675 38.682 -2.983 1.00 25.43 ? 208 ASP A OD2 1 ATOM 1217 N N . LYS A 1 156 ? -22.102 39.349 -8.031 1.00 29.29 ? 209 LYS A N 1 ATOM 1218 C CA . LYS A 1 156 ? -22.343 40.036 -9.302 1.00 32.88 ? 209 LYS A CA 1 ATOM 1219 C C . LYS A 1 156 ? -23.741 39.785 -9.855 1.00 31.69 ? 209 LYS A C 1 ATOM 1220 O O . LYS A 1 156 ? -24.163 40.434 -10.805 1.00 33.03 ? 209 LYS A O 1 ATOM 1221 C CB . LYS A 1 156 ? -21.302 39.639 -10.350 1.00 35.62 ? 209 LYS A CB 1 ATOM 1222 C CG . LYS A 1 156 ? -20.263 40.715 -10.611 1.00 37.64 ? 209 LYS A CG 1 ATOM 1223 C CD . LYS A 1 156 ? -19.031 40.141 -11.279 1.00 38.97 ? 209 LYS A CD 1 ATOM 1224 C CE . LYS A 1 156 ? -18.359 39.101 -10.386 1.00 41.24 ? 209 LYS A CE 1 ATOM 1225 N NZ . LYS A 1 156 ? -16.980 39.526 -9.977 1.00 41.67 ? 209 LYS A NZ 1 ATOM 1226 N N . ASN A 1 157 ? -24.460 38.850 -9.258 1.00 31.62 ? 210 ASN A N 1 ATOM 1227 C CA . ASN A 1 157 ? -25.884 38.713 -9.526 1.00 34.32 ? 210 ASN A CA 1 ATOM 1228 C C . ASN A 1 157 ? -26.656 38.251 -8.294 1.00 29.23 ? 210 ASN A C 1 ATOM 1229 O O . ASN A 1 157 ? -26.687 37.070 -7.984 1.00 24.40 ? 210 ASN A O 1 ATOM 1230 C CB . ASN A 1 157 ? -26.100 37.723 -10.672 1.00 37.70 ? 210 ASN A CB 1 ATOM 1231 C CG . ASN A 1 157 ? -27.527 37.720 -11.181 1.00 41.69 ? 210 ASN A CG 1 ATOM 1232 O OD1 . ASN A 1 157 ? -28.439 38.268 -10.544 1.00 42.60 ? 210 ASN A OD1 1 ATOM 1233 N ND2 . ASN A 1 157 ? -27.733 37.099 -12.337 1.00 42.71 ? 210 ASN A ND2 1 ATOM 1234 N N . SER A 1 158 ? -27.284 39.196 -7.607 1.00 29.12 ? 211 SER A N 1 ATOM 1235 C CA . SER A 1 158 ? -27.753 38.980 -6.242 1.00 27.77 ? 211 SER A CA 1 ATOM 1236 C C . SER A 1 158 ? -28.959 38.031 -6.124 1.00 28.16 ? 211 SER A C 1 ATOM 1237 O O . SER A 1 158 ? -29.405 37.717 -5.021 1.00 27.97 ? 211 SER A O 1 ATOM 1238 C CB . SER A 1 158 ? -28.100 40.316 -5.615 1.00 25.28 ? 211 SER A CB 1 ATOM 1239 O OG . SER A 1 158 ? -28.893 41.090 -6.482 1.00 25.44 ? 211 SER A OG 1 ATOM 1240 N N . VAL A 1 159 ? -29.476 37.567 -7.254 1.00 28.34 ? 212 VAL A N 1 ATOM 1241 C CA . VAL A 1 159 ? -30.636 36.688 -7.251 1.00 28.52 ? 212 VAL A CA 1 ATOM 1242 C C . VAL A 1 159 ? -30.193 35.250 -7.320 1.00 29.29 ? 212 VAL A C 1 ATOM 1243 O O . VAL A 1 159 ? -30.996 34.333 -7.147 1.00 31.49 ? 212 VAL A O 1 ATOM 1244 C CB . VAL A 1 159 ? -31.566 36.963 -8.448 1.00 30.44 ? 212 VAL A CB 1 ATOM 1245 C CG1 . VAL A 1 159 ? -31.816 38.448 -8.606 1.00 32.24 ? 212 VAL A CG1 1 ATOM 1246 C CG2 . VAL A 1 159 ? -30.981 36.380 -9.729 1.00 29.88 ? 212 VAL A CG2 1 ATOM 1247 N N . ASN A 1 160 ? -28.913 35.046 -7.597 1.00 30.60 ? 213 ASN A N 1 ATOM 1248 C CA . ASN A 1 160 ? -28.386 33.700 -7.748 1.00 32.03 ? 213 ASN A CA 1 ATOM 1249 C C . ASN A 1 160 ? -27.480 33.300 -6.598 1.00 33.63 ? 213 ASN A C 1 ATOM 1250 O O . ASN A 1 160 ? -26.965 34.154 -5.864 1.00 31.35 ? 213 ASN A O 1 ATOM 1251 C CB . ASN A 1 160 ? -27.600 33.581 -9.048 1.00 32.75 ? 213 ASN A CB 1 ATOM 1252 C CG . ASN A 1 160 ? -28.486 33.621 -10.273 1.00 33.82 ? 213 ASN A CG 1 ATOM 1253 O OD1 . ASN A 1 160 ? -29.642 33.190 -10.234 1.00 32.14 ? 213 ASN A OD1 1 ATOM 1254 N ND2 . ASN A 1 160 ? -27.942 34.134 -11.379 1.00 33.49 ? 213 ASN A ND2 1 ATOM 1255 N N . HIS A 1 161 ? -27.271 31.992 -6.479 1.00 34.00 ? 214 HIS A N 1 ATOM 1256 C CA . HIS A 1 161 ? -26.280 31.425 -5.581 1.00 34.20 ? 214 HIS A CA 1 ATOM 1257 C C . HIS A 1 161 ? -25.103 30.825 -6.357 1.00 34.07 ? 214 HIS A C 1 ATOM 1258 O O . HIS A 1 161 ? -25.286 30.288 -7.445 1.00 32.81 ? 214 HIS A O 1 ATOM 1259 C CB . HIS A 1 161 ? -26.934 30.334 -4.733 1.00 34.40 ? 214 HIS A CB 1 ATOM 1260 C CG . HIS A 1 161 ? -27.921 30.852 -3.737 1.00 37.04 ? 214 HIS A CG 1 ATOM 1261 N ND1 . HIS A 1 161 ? -29.258 30.517 -3.770 1.00 39.96 ? 214 HIS A ND1 1 ATOM 1262 C CD2 . HIS A 1 161 ? -27.764 31.667 -2.667 1.00 39.53 ? 214 HIS A CD2 1 ATOM 1263 C CE1 . HIS A 1 161 ? -29.884 31.115 -2.772 1.00 39.23 ? 214 HIS A CE1 1 ATOM 1264 N NE2 . HIS A 1 161 ? -29.001 31.817 -2.087 1.00 39.26 ? 214 HIS A NE2 1 ATOM 1265 N N . VAL A 1 162 ? -23.901 30.894 -5.790 1.00 31.68 ? 215 VAL A N 1 ATOM 1266 C CA . VAL A 1 162 ? -22.753 30.209 -6.376 1.00 34.01 ? 215 VAL A CA 1 ATOM 1267 C C . VAL A 1 162 ? -21.991 29.396 -5.347 1.00 33.07 ? 215 VAL A C 1 ATOM 1268 O O . VAL A 1 162 ? -22.164 29.579 -4.148 1.00 38.24 ? 215 VAL A O 1 ATOM 1269 C CB . VAL A 1 162 ? -21.771 31.200 -6.993 1.00 36.46 ? 215 VAL A CB 1 ATOM 1270 C CG1 . VAL A 1 162 ? -21.434 30.798 -8.420 1.00 36.13 ? 215 VAL A CG1 1 ATOM 1271 C CG2 . VAL A 1 162 ? -22.339 32.609 -6.940 1.00 37.56 ? 215 VAL A CG2 1 ATOM 1272 N N . ILE A 1 163 ? -21.123 28.510 -5.812 1.00 31.23 ? 216 ILE A N 1 ATOM 1273 C CA . ILE A 1 163 ? -20.121 27.930 -4.938 1.00 31.49 ? 216 ILE A CA 1 ATOM 1274 C C . ILE A 1 163 ? -18.892 28.825 -4.813 1.00 32.95 ? 216 ILE A C 1 ATOM 1275 O O . ILE A 1 163 ? -18.370 29.333 -5.802 1.00 33.93 ? 216 ILE A O 1 ATOM 1276 C CB . ILE A 1 163 ? -19.733 26.538 -5.419 1.00 31.94 ? 216 ILE A CB 1 ATOM 1277 C CG1 . ILE A 1 163 ? -20.825 25.543 -5.031 1.00 31.65 ? 216 ILE A CG1 1 ATOM 1278 C CG2 . ILE A 1 163 ? -18.403 26.125 -4.817 1.00 31.93 ? 216 ILE A CG2 1 ATOM 1279 C CD1 . ILE A 1 163 ? -20.906 24.367 -5.939 1.00 32.23 ? 216 ILE A CD1 1 ATOM 1280 N N . HIS A 1 164 ? -18.467 29.029 -3.568 1.00 30.77 ? 217 HIS A N 1 ATOM 1281 C CA . HIS A 1 164 ? -17.346 29.890 -3.238 1.00 27.82 ? 217 HIS A CA 1 ATOM 1282 C C . HIS A 1 164 ? -16.193 29.014 -2.790 1.00 27.14 ? 217 HIS A C 1 ATOM 1283 O O . HIS A 1 164 ? -16.411 27.964 -2.198 1.00 28.21 ? 217 HIS A O 1 ATOM 1284 C CB . HIS A 1 164 ? -17.733 30.839 -2.105 1.00 27.34 ? 217 HIS A CB 1 ATOM 1285 C CG . HIS A 1 164 ? -18.723 31.884 -2.513 1.00 27.77 ? 217 HIS A CG 1 ATOM 1286 N ND1 . HIS A 1 164 ? -18.347 33.143 -2.919 1.00 27.58 ? 217 HIS A ND1 1 ATOM 1287 C CD2 . HIS A 1 164 ? -20.073 31.851 -2.598 1.00 26.93 ? 217 HIS A CD2 1 ATOM 1288 C CE1 . HIS A 1 164 ? -19.422 33.840 -3.239 1.00 27.67 ? 217 HIS A CE1 1 ATOM 1289 N NE2 . HIS A 1 164 ? -20.482 33.079 -3.049 1.00 25.32 ? 217 HIS A NE2 1 ATOM 1290 N N . ILE A 1 165 ? -14.967 29.443 -3.064 1.00 26.35 ? 218 ILE A N 1 ATOM 1291 C CA . ILE A 1 165 ? -13.807 28.902 -2.367 1.00 27.29 ? 218 ILE A CA 1 ATOM 1292 C C . ILE A 1 165 ? -13.058 30.039 -1.715 1.00 24.15 ? 218 ILE A C 1 ATOM 1293 O O . ILE A 1 165 ? -12.712 31.014 -2.371 1.00 22.10 ? 218 ILE A O 1 ATOM 1294 C CB . ILE A 1 165 ? -12.870 28.157 -3.336 1.00 28.21 ? 218 ILE A CB 1 ATOM 1295 C CG1 . ILE A 1 165 ? -13.672 27.225 -4.234 1.00 30.35 ? 218 ILE A CG1 1 ATOM 1296 C CG2 . ILE A 1 165 ? -11.832 27.353 -2.568 1.00 28.62 ? 218 ILE A CG2 1 ATOM 1297 C CD1 . ILE A 1 165 ? -13.478 25.769 -3.905 1.00 31.39 ? 218 ILE A CD1 1 ATOM 1298 N N . ASP A 1 166 ? -12.810 29.911 -0.419 1.00 23.29 ? 219 ASP A N 1 ATOM 1299 C CA . ASP A 1 166 ? -12.062 30.929 0.310 1.00 23.46 ? 219 ASP A CA 1 ATOM 1300 C C . ASP A 1 166 ? -11.088 30.267 1.280 1.00 20.88 ? 219 ASP A C 1 ATOM 1301 O O . ASP A 1 166 ? -11.172 29.067 1.530 1.00 24.62 ? 219 ASP A O 1 ATOM 1302 C CB . ASP A 1 166 ? -13.020 31.853 1.058 1.00 23.81 ? 219 ASP A CB 1 ATOM 1303 C CG . ASP A 1 166 ? -12.414 33.189 1.365 1.00 27.01 ? 219 ASP A CG 1 ATOM 1304 O OD1 . ASP A 1 166 ? -11.232 33.405 1.021 1.00 28.34 ? 219 ASP A OD1 1 ATOM 1305 O OD2 . ASP A 1 166 ? -13.036 34.104 1.945 1.00 28.42 ? 219 ASP A OD2 1 ATOM 1306 N N . GLN A 1 167 ? -10.160 31.052 1.818 1.00 21.74 ? 220 GLN A N 1 ATOM 1307 C CA . GLN A 1 167 ? -9.289 30.577 2.887 1.00 20.90 ? 220 GLN A CA 1 ATOM 1308 C C . GLN A 1 167 ? -10.103 30.314 4.149 1.00 22.50 ? 220 GLN A C 1 ATOM 1309 O O . GLN A 1 167 ? -11.088 30.996 4.412 1.00 22.00 ? 220 GLN A O 1 ATOM 1310 C CB . GLN A 1 167 ? -8.197 31.603 3.162 1.00 21.29 ? 220 GLN A CB 1 ATOM 1311 C CG . GLN A 1 167 ? -8.685 32.840 3.888 1.00 20.08 ? 220 GLN A CG 1 ATOM 1312 C CD . GLN A 1 167 ? -7.663 33.959 3.877 1.00 20.57 ? 220 GLN A CD 1 ATOM 1313 O OE1 . GLN A 1 167 ? -6.795 34.001 3.010 1.00 26.20 ? 220 GLN A OE1 1 ATOM 1314 N NE2 . GLN A 1 167 ? -7.764 34.868 4.833 1.00 19.45 ? 220 GLN A NE2 1 ATOM 1315 N N . PRO A 1 168 ? -9.709 29.310 4.924 1.00 24.60 ? 221 PRO A N 1 ATOM 1316 C CA . PRO A 1 168 ? -10.433 28.956 6.152 1.00 24.05 ? 221 PRO A CA 1 ATOM 1317 C C . PRO A 1 168 ? -10.082 29.862 7.322 1.00 25.50 ? 221 PRO A C 1 ATOM 1318 O O . PRO A 1 168 ? -9.064 30.535 7.267 1.00 24.39 ? 221 PRO A O 1 ATOM 1319 C CB . PRO A 1 168 ? -9.969 27.531 6.429 1.00 24.30 ? 221 PRO A CB 1 ATOM 1320 C CG . PRO A 1 168 ? -8.575 27.469 5.840 1.00 25.49 ? 221 PRO A CG 1 ATOM 1321 C CD . PRO A 1 168 ? -8.565 28.420 4.674 1.00 24.95 ? 221 PRO A CD 1 ATOM 1322 N N . ARG A 1 169 ? -10.933 29.874 8.349 1.00 27.52 ? 222 ARG A N 1 ATOM 1323 C CA . ARG A 1 169 ? -10.626 30.477 9.643 1.00 29.42 ? 222 ARG A CA 1 ATOM 1324 C C . ARG A 1 169 ? -9.679 29.606 10.450 1.00 27.71 ? 222 ARG A C 1 ATOM 1325 O O . ARG A 1 169 ? -9.596 28.398 10.229 1.00 30.08 ? 222 ARG A O 1 ATOM 1326 C CB . ARG A 1 169 ? -11.918 30.661 10.446 1.00 35.17 ? 222 ARG A CB 1 ATOM 1327 C CG . ARG A 1 169 ? -12.647 31.968 10.178 1.00 41.29 ? 222 ARG A CG 1 ATOM 1328 C CD . ARG A 1 169 ? -14.101 31.987 10.660 1.00 45.62 ? 222 ARG A CD 1 ATOM 1329 N NE . ARG A 1 169 ? -14.378 33.116 11.551 1.00 49.86 ? 222 ARG A NE 1 ATOM 1330 C CZ . ARG A 1 169 ? -15.600 33.536 11.869 1.00 53.37 ? 222 ARG A CZ 1 ATOM 1331 N NH1 . ARG A 1 169 ? -16.667 32.927 11.366 1.00 54.60 ? 222 ARG A NH1 1 ATOM 1332 N NH2 . ARG A 1 169 ? -15.759 34.567 12.693 1.00 53.78 ? 222 ARG A NH2 1 ATOM 1333 N N . LEU A 1 170 ? -8.999 30.209 11.419 1.00 24.00 ? 223 LEU A N 1 ATOM 1334 C CA . LEU A 1 170 ? -8.015 29.486 12.214 1.00 23.75 ? 223 LEU A CA 1 ATOM 1335 C C . LEU A 1 170 ? -8.496 29.226 13.633 1.00 20.31 ? 223 LEU A C 1 ATOM 1336 O O . LEU A 1 170 ? -9.522 29.741 14.063 1.00 18.04 ? 223 LEU A O 1 ATOM 1337 C CB . LEU A 1 170 ? -6.698 30.256 12.264 1.00 24.27 ? 223 LEU A CB 1 ATOM 1338 C CG . LEU A 1 170 ? -6.290 30.812 10.903 1.00 25.19 ? 223 LEU A CG 1 ATOM 1339 C CD1 . LEU A 1 170 ? -5.335 31.977 11.067 1.00 21.17 ? 223 LEU A CD1 1 ATOM 1340 C CD2 . LEU A 1 170 ? -5.687 29.685 10.061 1.00 26.47 ? 223 LEU A CD2 1 ATOM 1341 N N . GLY A 1 171 ? -7.740 28.408 14.355 1.00 18.80 ? 224 GLY A N 1 ATOM 1342 C CA . GLY A 1 171 ? -8.126 28.005 15.698 1.00 18.83 ? 224 GLY A CA 1 ATOM 1343 C C . GLY A 1 171 ? -7.841 29.099 16.710 1.00 17.98 ? 224 GLY A C 1 ATOM 1344 O O . GLY A 1 171 ? -8.475 29.164 17.762 1.00 18.84 ? 224 GLY A O 1 ATOM 1345 N N . LEU A 1 172 ? -6.884 29.963 16.388 1.00 17.40 ? 225 LEU A N 1 ATOM 1346 C CA . LEU A 1 172 ? -6.740 31.217 17.109 1.00 19.33 ? 225 LEU A CA 1 ATOM 1347 C C . LEU A 1 172 ? -7.427 32.349 16.359 1.00 18.70 ? 225 LEU A C 1 ATOM 1348 O O . LEU A 1 172 ? -7.725 32.218 15.181 1.00 18.00 ? 225 LEU A O 1 ATOM 1349 C CB . LEU A 1 172 ? -5.256 31.515 17.357 1.00 20.45 ? 225 LEU A CB 1 ATOM 1350 C CG . LEU A 1 172 ? -4.687 30.456 18.301 1.00 20.15 ? 225 LEU A CG 1 ATOM 1351 C CD1 . LEU A 1 172 ? -3.346 30.011 17.843 1.00 21.91 ? 225 LEU A CD1 1 ATOM 1352 C CD2 . LEU A 1 172 ? -4.675 30.956 19.745 1.00 22.16 ? 225 LEU A CD2 1 ATOM 1353 N N . PRO A 1 173 ? -7.711 33.433 17.075 1.00 18.53 ? 226 PRO A N 1 ATOM 1354 C CA . PRO A 1 173 ? -8.547 34.540 16.589 1.00 19.05 ? 226 PRO A CA 1 ATOM 1355 C C . PRO A 1 173 ? -8.060 35.214 15.305 1.00 19.97 ? 226 PRO A C 1 ATOM 1356 O O . PRO A 1 173 ? -8.886 35.625 14.491 1.00 18.68 ? 226 PRO A O 1 ATOM 1357 C CB . PRO A 1 173 ? -8.480 35.544 17.747 1.00 20.54 ? 226 PRO A CB 1 ATOM 1358 C CG . PRO A 1 173 ? -8.205 34.711 18.951 1.00 20.72 ? 226 PRO A CG 1 ATOM 1359 C CD . PRO A 1 173 ? -7.269 33.645 18.464 1.00 20.76 ? 226 PRO A CD 1 ATOM 1360 N N . SER A 1 174 ? -6.749 35.347 15.127 1.00 18.93 ? 227 SER A N 1 ATOM 1361 C CA . SER A 1 174 ? -6.229 35.956 13.907 1.00 21.17 ? 227 SER A CA 1 ATOM 1362 C C . SER A 1 174 ? -4.875 35.387 13.512 1.00 20.84 ? 227 SER A C 1 ATOM 1363 O O . SER A 1 174 ? -4.204 34.743 14.315 1.00 23.27 ? 227 SER A O 1 ATOM 1364 C CB . SER A 1 174 ? -6.102 37.469 14.075 1.00 22.18 ? 227 SER A CB 1 ATOM 1365 O OG . SER A 1 174 ? -4.962 37.793 14.842 1.00 19.95 ? 227 SER A OG 1 ATOM 1366 N N . ARG A 1 175 ? -4.469 35.653 12.275 1.00 19.53 ? 228 ARG A N 1 ATOM 1367 C CA . ARG A 1 175 ? -3.225 35.109 11.757 1.00 21.64 ? 228 ARG A CA 1 ATOM 1368 C C . ARG A 1 175 ? -2.043 35.626 12.579 1.00 18.96 ? 228 ARG A C 1 ATOM 1369 O O . ARG A 1 175 ? -1.041 34.953 12.713 1.00 16.18 ? 228 ARG A O 1 ATOM 1370 C CB . ARG A 1 175 ? -3.058 35.469 10.280 1.00 22.14 ? 228 ARG A CB 1 ATOM 1371 C CG . ARG A 1 175 ? -2.870 36.956 10.026 1.00 25.16 ? 228 ARG A CG 1 ATOM 1372 C CD . ARG A 1 175 ? -3.036 37.379 8.564 1.00 25.89 ? 228 ARG A CD 1 ATOM 1373 N NE . ARG A 1 175 ? -2.136 36.657 7.666 1.00 30.04 ? 228 ARG A NE 1 ATOM 1374 C CZ . ARG A 1 175 ? -0.855 36.961 7.467 1.00 31.47 ? 228 ARG A CZ 1 ATOM 1375 N NH1 . ARG A 1 175 ? -0.311 37.982 8.100 1.00 30.83 ? 228 ARG A NH1 1 ATOM 1376 N NH2 . ARG A 1 175 ? -0.114 36.241 6.625 1.00 30.35 ? 228 ARG A NH2 1 ATOM 1377 N N . ASP A 1 176 ? -2.186 36.815 13.151 1.00 20.74 ? 229 ASP A N 1 ATOM 1378 C CA . ASP A 1 176 ? -1.131 37.412 13.958 1.00 20.29 ? 229 ASP A CA 1 ATOM 1379 C C . ASP A 1 176 ? -0.746 36.543 15.147 1.00 19.46 ? 229 ASP A C 1 ATOM 1380 O O . ASP A 1 176 ? 0.411 36.499 15.543 1.00 22.44 ? 229 ASP A O 1 ATOM 1381 C CB . ASP A 1 176 ? -1.575 38.766 14.484 1.00 20.43 ? 229 ASP A CB 1 ATOM 1382 C CG . ASP A 1 176 ? -2.246 39.600 13.441 1.00 21.11 ? 229 ASP A CG 1 ATOM 1383 O OD1 . ASP A 1 176 ? -3.446 39.357 13.174 1.00 24.70 ? 229 ASP A OD1 1 ATOM 1384 O OD2 . ASP A 1 176 ? -1.662 40.543 12.855 1.00 24.62 ? 229 ASP A OD2 1 ATOM 1385 N N . TYR A 1 177 ? -1.724 35.882 15.744 1.00 18.00 ? 230 TYR A N 1 ATOM 1386 C CA . TYR A 1 177 ? -1.480 35.141 16.970 1.00 19.13 ? 230 TYR A CA 1 ATOM 1387 C C . TYR A 1 177 ? -0.346 34.140 16.757 1.00 20.63 ? 230 TYR A C 1 ATOM 1388 O O . TYR A 1 177 ? 0.398 33.818 17.685 1.00 24.28 ? 230 TYR A O 1 ATOM 1389 C CB . TYR A 1 177 ? -2.757 34.425 17.416 1.00 19.52 ? 230 TYR A CB 1 ATOM 1390 C CG . TYR A 1 177 ? -3.581 35.221 18.391 1.00 18.64 ? 230 TYR A CG 1 ATOM 1391 C CD1 . TYR A 1 177 ? -4.337 36.303 17.965 1.00 21.13 ? 230 TYR A CD1 1 ATOM 1392 C CD2 . TYR A 1 177 ? -3.625 34.883 19.736 1.00 22.01 ? 230 TYR A CD2 1 ATOM 1393 C CE1 . TYR A 1 177 ? -5.113 37.030 18.853 1.00 19.99 ? 230 TYR A CE1 1 ATOM 1394 C CE2 . TYR A 1 177 ? -4.402 35.604 20.632 1.00 19.88 ? 230 TYR A CE2 1 ATOM 1395 C CZ . TYR A 1 177 ? -5.141 36.674 20.188 1.00 21.39 ? 230 TYR A CZ 1 ATOM 1396 O OH . TYR A 1 177 ? -5.910 37.403 21.078 1.00 22.70 ? 230 TYR A OH 1 ATOM 1397 N N . TYR A 1 178 ? -0.216 33.655 15.528 1.00 19.38 ? 231 TYR A N 1 ATOM 1398 C CA . TYR A 1 178 ? 0.673 32.543 15.233 1.00 22.70 ? 231 TYR A CA 1 ATOM 1399 C C . TYR A 1 178 ? 2.142 32.985 15.227 1.00 24.15 ? 231 TYR A C 1 ATOM 1400 O O . TYR A 1 178 ? 3.043 32.168 15.056 1.00 22.97 ? 231 TYR A O 1 ATOM 1401 C CB . TYR A 1 178 ? 0.260 31.878 13.912 1.00 23.06 ? 231 TYR A CB 1 ATOM 1402 C CG . TYR A 1 178 ? -1.057 31.153 14.066 1.00 24.74 ? 231 TYR A CG 1 ATOM 1403 C CD1 . TYR A 1 178 ? -2.263 31.796 13.815 1.00 24.00 ? 231 TYR A CD1 1 ATOM 1404 C CD2 . TYR A 1 178 ? -1.099 29.845 14.530 1.00 24.62 ? 231 TYR A CD2 1 ATOM 1405 C CE1 . TYR A 1 178 ? -3.470 31.145 13.994 1.00 23.24 ? 231 TYR A CE1 1 ATOM 1406 C CE2 . TYR A 1 178 ? -2.299 29.190 14.713 1.00 24.24 ? 231 TYR A CE2 1 ATOM 1407 C CZ . TYR A 1 178 ? -3.484 29.846 14.449 1.00 24.20 ? 231 TYR A CZ 1 ATOM 1408 O OH . TYR A 1 178 ? -4.686 29.191 14.628 1.00 23.97 ? 231 TYR A OH 1 ATOM 1409 N N . GLU A 1 179 ? 2.374 34.272 15.463 1.00 26.91 ? 232 GLU A N 1 ATOM 1410 C CA . GLU A 1 179 ? 3.682 34.745 15.895 1.00 28.40 ? 232 GLU A CA 1 ATOM 1411 C C . GLU A 1 179 ? 4.104 34.058 17.189 1.00 26.93 ? 232 GLU A C 1 ATOM 1412 O O . GLU A 1 179 ? 5.242 33.587 17.317 1.00 24.91 ? 232 GLU A O 1 ATOM 1413 C CB . GLU A 1 179 ? 3.661 36.259 16.101 1.00 30.75 ? 232 GLU A CB 1 ATOM 1414 C CG . GLU A 1 179 ? 3.540 37.087 14.831 1.00 34.18 ? 232 GLU A CG 1 ATOM 1415 C CD . GLU A 1 179 ? 3.310 38.567 15.128 1.00 37.40 ? 232 GLU A CD 1 ATOM 1416 O OE1 . GLU A 1 179 ? 2.366 39.179 14.564 1.00 35.95 ? 232 GLU A OE1 1 ATOM 1417 O OE2 . GLU A 1 179 ? 4.080 39.119 15.944 1.00 41.55 ? 232 GLU A OE2 1 ATOM 1418 N N . CYS A 1 180 ? 3.182 34.014 18.147 1.00 25.78 ? 233 CYS A N 1 ATOM 1419 C CA . CYS A 1 180 ? 3.337 33.160 19.316 1.00 22.02 ? 233 CYS A CA 1 ATOM 1420 C C . CYS A 1 180 ? 4.445 33.672 20.216 1.00 22.99 ? 233 CYS A C 1 ATOM 1421 O O . CYS A 1 180 ? 5.005 32.923 21.015 1.00 27.38 ? 233 CYS A O 1 ATOM 1422 C CB . CYS A 1 180 ? 3.646 31.727 18.889 1.00 19.08 ? 233 CYS A CB 1 ATOM 1423 S SG . CYS A 1 180 ? 2.214 30.880 18.186 1.00 23.26 ? 233 CYS A SG 1 ATOM 1424 N N . THR A 1 181 ? 4.750 34.952 20.107 1.00 23.29 ? 234 THR A N 1 ATOM 1425 C CA . THR A 1 181 ? 5.623 35.583 21.084 1.00 26.32 ? 234 THR A CA 1 ATOM 1426 C C . THR A 1 181 ? 4.892 36.706 21.793 1.00 27.53 ? 234 THR A C 1 ATOM 1427 O O . THR A 1 181 ? 3.772 37.069 21.424 1.00 25.72 ? 234 THR A O 1 ATOM 1428 C CB . THR A 1 181 ? 6.850 36.160 20.400 1.00 26.88 ? 234 THR A CB 1 ATOM 1429 O OG1 . THR A 1 181 ? 6.436 37.108 19.404 1.00 22.39 ? 234 THR A OG1 1 ATOM 1430 C CG2 . THR A 1 181 ? 7.615 35.077 19.630 1.00 28.03 ? 234 THR A CG2 1 ATOM 1431 N N . GLY A 1 182 ? 5.550 37.273 22.800 1.00 27.40 ? 235 GLY A N 1 ATOM 1432 C CA . GLY A 1 182 ? 5.068 38.482 23.427 1.00 24.93 ? 235 GLY A CA 1 ATOM 1433 C C . GLY A 1 182 ? 3.602 38.299 23.766 1.00 25.30 ? 235 GLY A C 1 ATOM 1434 O O . GLY A 1 182 ? 3.224 37.321 24.417 1.00 20.56 ? 235 GLY A O 1 ATOM 1435 N N . ILE A 1 183 ? 2.774 39.235 23.323 1.00 23.98 ? 236 ILE A N 1 ATOM 1436 C CA . ILE A 1 183 ? 1.409 39.299 23.816 1.00 25.47 ? 236 ILE A CA 1 ATOM 1437 C C . ILE A 1 183 ? 0.637 38.076 23.363 1.00 24.91 ? 236 ILE A C 1 ATOM 1438 O O . ILE A 1 183 ? -0.493 37.891 23.785 1.00 28.00 ? 236 ILE A O 1 ATOM 1439 C CB . ILE A 1 183 ? 0.697 40.569 23.330 1.00 24.50 ? 236 ILE A CB 1 ATOM 1440 C CG1 . ILE A 1 183 ? 0.613 40.567 21.801 1.00 24.66 ? 236 ILE A CG1 1 ATOM 1441 C CG2 . ILE A 1 183 ? 1.416 41.815 23.872 1.00 24.23 ? 236 ILE A CG2 1 ATOM 1442 C CD1 . ILE A 1 183 ? 0.248 41.911 21.211 1.00 25.68 ? 236 ILE A CD1 1 ATOM 1443 N N . TYR A 1 184 ? 1.249 37.248 22.513 1.00 22.62 ? 237 TYR A N 1 ATOM 1444 C CA . TYR A 1 184 ? 0.567 36.085 21.948 1.00 22.96 ? 237 TYR A CA 1 ATOM 1445 C C . TYR A 1 184 ? 1.025 34.763 22.568 1.00 27.14 ? 237 TYR A C 1 ATOM 1446 O O . TYR A 1 184 ? 0.438 33.713 22.301 1.00 28.75 ? 237 TYR A O 1 ATOM 1447 C CB . TYR A 1 184 ? 0.762 36.030 20.425 1.00 21.84 ? 237 TYR A CB 1 ATOM 1448 C CG . TYR A 1 184 ? 0.183 37.222 19.691 1.00 19.39 ? 237 TYR A CG 1 ATOM 1449 C CD1 . TYR A 1 184 ? -1.175 37.498 19.721 1.00 18.98 ? 237 TYR A CD1 1 ATOM 1450 C CD2 . TYR A 1 184 ? 0.996 38.072 18.978 1.00 21.03 ? 237 TYR A CD2 1 ATOM 1451 C CE1 . TYR A 1 184 ? -1.695 38.596 19.048 1.00 18.13 ? 237 TYR A CE1 1 ATOM 1452 C CE2 . TYR A 1 184 ? 0.494 39.163 18.311 1.00 22.75 ? 237 TYR A CE2 1 ATOM 1453 C CZ . TYR A 1 184 ? -0.851 39.424 18.343 1.00 21.45 ? 237 TYR A CZ 1 ATOM 1454 O OH . TYR A 1 184 ? -1.287 40.529 17.658 1.00 23.10 ? 237 TYR A OH 1 ATOM 1455 N N . LYS A 1 185 ? 2.062 34.807 23.396 1.00 29.59 ? 238 LYS A N 1 ATOM 1456 C CA . LYS A 1 185 ? 2.700 33.581 23.871 1.00 32.29 ? 238 LYS A CA 1 ATOM 1457 C C . LYS A 1 185 ? 1.733 32.699 24.655 1.00 29.53 ? 238 LYS A C 1 ATOM 1458 O O . LYS A 1 185 ? 1.632 31.501 24.404 1.00 30.12 ? 238 LYS A O 1 ATOM 1459 C CB . LYS A 1 185 ? 3.938 33.892 24.729 1.00 35.27 ? 238 LYS A CB 1 ATOM 1460 C CG . LYS A 1 185 ? 4.832 32.676 25.008 1.00 38.36 ? 238 LYS A CG 1 ATOM 1461 C CD . LYS A 1 185 ? 6.301 33.067 25.225 1.00 41.97 ? 238 LYS A CD 1 ATOM 1462 C CE . LYS A 1 185 ? 6.752 32.861 26.683 1.00 44.85 ? 238 LYS A CE 1 ATOM 1463 N NZ . LYS A 1 185 ? 7.583 31.627 26.888 1.00 46.29 ? 238 LYS A NZ 1 ATOM 1464 N N . GLU A 1 186 ? 1.031 33.273 25.620 1.00 30.00 ? 239 GLU A N 1 ATOM 1465 C CA . GLU A 1 186 ? 0.178 32.457 26.464 1.00 29.58 ? 239 GLU A CA 1 ATOM 1466 C C . GLU A 1 186 ? -0.833 31.739 25.584 1.00 25.59 ? 239 GLU A C 1 ATOM 1467 O O . GLU A 1 186 ? -1.078 30.554 25.759 1.00 24.71 ? 239 GLU A O 1 ATOM 1468 C CB . GLU A 1 186 ? -0.542 33.295 27.521 1.00 32.51 ? 239 GLU A CB 1 ATOM 1469 C CG . GLU A 1 186 ? -1.508 32.481 28.382 1.00 34.49 ? 239 GLU A CG 1 ATOM 1470 C CD . GLU A 1 186 ? -0.863 31.270 29.055 1.00 36.28 ? 239 GLU A CD 1 ATOM 1471 O OE1 . GLU A 1 186 ? 0.382 31.165 29.044 1.00 40.44 ? 239 GLU A OE1 1 ATOM 1472 O OE2 . GLU A 1 186 ? -1.601 30.421 29.613 1.00 35.94 ? 239 GLU A OE2 1 ATOM 1473 N N . ALA A 1 187 ? -1.398 32.468 24.625 1.00 23.29 ? 240 ALA A N 1 ATOM 1474 C CA . ALA A 1 187 ? -2.455 31.936 23.790 1.00 21.50 ? 240 ALA A CA 1 ATOM 1475 C C . ALA A 1 187 ? -1.956 30.720 23.048 1.00 19.90 ? 240 ALA A C 1 ATOM 1476 O O . ALA A 1 187 ? -2.606 29.686 23.033 1.00 19.88 ? 240 ALA A O 1 ATOM 1477 C CB . ALA A 1 187 ? -2.943 32.993 22.820 1.00 23.70 ? 240 ALA A CB 1 ATOM 1478 N N . CYS A 1 188 ? -0.791 30.836 22.426 1.00 20.09 ? 241 CYS A N 1 ATOM 1479 C CA . CYS A 1 188 ? -0.271 29.727 21.654 1.00 21.61 ? 241 CYS A CA 1 ATOM 1480 C C . CYS A 1 188 ? 0.018 28.568 22.581 1.00 22.34 ? 241 CYS A C 1 ATOM 1481 O O . CYS A 1 188 ? -0.211 27.417 22.236 1.00 23.07 ? 241 CYS A O 1 ATOM 1482 C CB . CYS A 1 188 ? 0.979 30.133 20.896 1.00 21.41 ? 241 CYS A CB 1 ATOM 1483 S SG . CYS A 1 188 ? 0.632 31.131 19.446 1.00 21.29 ? 241 CYS A SG 1 ATOM 1484 N N . THR A 1 189 ? 0.487 28.880 23.777 1.00 22.72 ? 242 THR A N 1 ATOM 1485 C CA . THR A 1 189 ? 0.823 27.843 24.733 1.00 22.41 ? 242 THR A CA 1 ATOM 1486 C C . THR A 1 189 ? -0.445 27.202 25.281 1.00 24.16 ? 242 THR A C 1 ATOM 1487 O O . THR A 1 189 ? -0.535 25.977 25.408 1.00 24.44 ? 242 THR A O 1 ATOM 1488 C CB . THR A 1 189 ? 1.680 28.431 25.864 1.00 22.25 ? 242 THR A CB 1 ATOM 1489 O OG1 . THR A 1 189 ? 2.930 28.889 25.330 1.00 19.78 ? 242 THR A OG1 1 ATOM 1490 C CG2 . THR A 1 189 ? 2.071 27.360 26.886 1.00 20.47 ? 242 THR A CG2 1 ATOM 1491 N N . ALA A 1 190 ? -1.435 28.023 25.597 1.00 23.23 ? 243 ALA A N 1 ATOM 1492 C CA . ALA A 1 190 ? -2.713 27.498 26.059 1.00 21.17 ? 243 ALA A CA 1 ATOM 1493 C C . ALA A 1 190 ? -3.411 26.647 24.982 1.00 20.22 ? 243 ALA A C 1 ATOM 1494 O O . ALA A 1 190 ? -4.077 25.674 25.291 1.00 22.98 ? 243 ALA A O 1 ATOM 1495 C CB . ALA A 1 190 ? -3.591 28.617 26.503 1.00 19.70 ? 243 ALA A CB 1 ATOM 1496 N N . TYR A 1 191 ? -3.245 27.022 23.724 1.00 20.65 ? 244 TYR A N 1 ATOM 1497 C CA . TYR A 1 191 ? -3.911 26.360 22.602 1.00 20.95 ? 244 TYR A CA 1 ATOM 1498 C C . TYR A 1 191 ? -3.378 24.938 22.467 1.00 23.07 ? 244 TYR A C 1 ATOM 1499 O O . TYR A 1 191 ? -4.134 23.970 22.373 1.00 19.73 ? 244 TYR A O 1 ATOM 1500 C CB . TYR A 1 191 ? -3.657 27.180 21.327 1.00 17.92 ? 244 TYR A CB 1 ATOM 1501 C CG . TYR A 1 191 ? -4.293 26.703 20.049 1.00 18.61 ? 244 TYR A CG 1 ATOM 1502 C CD1 . TYR A 1 191 ? -3.543 26.638 18.875 1.00 18.77 ? 244 TYR A CD1 1 ATOM 1503 C CD2 . TYR A 1 191 ? -5.643 26.352 19.986 1.00 18.79 ? 244 TYR A CD2 1 ATOM 1504 C CE1 . TYR A 1 191 ? -4.104 26.214 17.683 1.00 18.07 ? 244 TYR A CE1 1 ATOM 1505 C CE2 . TYR A 1 191 ? -6.221 25.929 18.790 1.00 16.85 ? 244 TYR A CE2 1 ATOM 1506 C CZ . TYR A 1 191 ? -5.448 25.864 17.638 1.00 19.98 ? 244 TYR A CZ 1 ATOM 1507 O OH . TYR A 1 191 ? -5.984 25.448 16.429 1.00 17.74 ? 244 TYR A OH 1 ATOM 1508 N N . VAL A 1 192 ? -2.064 24.793 22.480 1.00 25.51 ? 245 VAL A N 1 ATOM 1509 C CA . VAL A 1 192 ? -1.494 23.476 22.268 1.00 26.80 ? 245 VAL A CA 1 ATOM 1510 C C . VAL A 1 192 ? -1.713 22.596 23.504 1.00 24.89 ? 245 VAL A C 1 ATOM 1511 O O . VAL A 1 192 ? -1.961 21.406 23.380 1.00 22.91 ? 245 VAL A O 1 ATOM 1512 C CB . VAL A 1 192 ? -0.014 23.572 21.868 1.00 29.17 ? 245 VAL A CB 1 ATOM 1513 C CG1 . VAL A 1 192 ? 0.690 22.249 22.081 1.00 29.16 ? 245 VAL A CG1 1 ATOM 1514 C CG2 . VAL A 1 192 ? 0.085 23.998 20.408 1.00 29.43 ? 245 VAL A CG2 1 ATOM 1515 N N . ASP A 1 193 ? -1.669 23.192 24.689 1.00 25.92 ? 246 ASP A N 1 ATOM 1516 C CA . ASP A 1 193 ? -1.938 22.453 25.918 1.00 26.55 ? 246 ASP A CA 1 ATOM 1517 C C . ASP A 1 193 ? -3.357 21.898 25.877 1.00 26.52 ? 246 ASP A C 1 ATOM 1518 O O . ASP A 1 193 ? -3.660 20.843 26.456 1.00 24.97 ? 246 ASP A O 1 ATOM 1519 C CB . ASP A 1 193 ? -1.761 23.357 27.141 1.00 27.66 ? 246 ASP A CB 1 ATOM 1520 C CG . ASP A 1 193 ? -0.300 23.468 27.597 1.00 27.91 ? 246 ASP A CG 1 ATOM 1521 O OD1 . ASP A 1 193 ? 0.608 22.920 26.933 1.00 26.83 ? 246 ASP A OD1 1 ATOM 1522 O OD2 . ASP A 1 193 ? 0.028 24.094 28.618 1.00 29.09 ? 246 ASP A OD2 1 ATOM 1523 N N . PHE A 1 194 ? -4.222 22.635 25.187 1.00 24.52 ? 247 PHE A N 1 ATOM 1524 C CA . PHE A 1 194 ? -5.644 22.346 25.144 1.00 22.18 ? 247 PHE A CA 1 ATOM 1525 C C . PHE A 1 194 ? -5.896 21.198 24.160 1.00 20.36 ? 247 PHE A C 1 ATOM 1526 O O . PHE A 1 194 ? -6.579 20.240 24.488 1.00 22.19 ? 247 PHE A O 1 ATOM 1527 C CB . PHE A 1 194 ? -6.404 23.623 24.748 1.00 24.59 ? 247 PHE A CB 1 ATOM 1528 C CG . PHE A 1 194 ? -7.879 23.417 24.508 1.00 23.75 ? 247 PHE A CG 1 ATOM 1529 C CD1 . PHE A 1 194 ? -8.553 24.202 23.597 1.00 24.16 ? 247 PHE A CD1 1 ATOM 1530 C CD2 . PHE A 1 194 ? -8.584 22.453 25.199 1.00 21.80 ? 247 PHE A CD2 1 ATOM 1531 C CE1 . PHE A 1 194 ? -9.903 24.025 23.376 1.00 23.61 ? 247 PHE A CE1 1 ATOM 1532 C CE2 . PHE A 1 194 ? -9.931 22.272 24.973 1.00 21.73 ? 247 PHE A CE2 1 ATOM 1533 C CZ . PHE A 1 194 ? -10.589 23.058 24.069 1.00 21.16 ? 247 PHE A CZ 1 ATOM 1534 N N . MET A 1 195 ? -5.308 21.275 22.973 1.00 18.99 ? 248 MET A N 1 ATOM 1535 C CA . MET A 1 195 ? -5.053 20.081 22.159 1.00 20.85 ? 248 MET A CA 1 ATOM 1536 C C . MET A 1 195 ? -4.654 18.905 23.002 1.00 20.62 ? 248 MET A C 1 ATOM 1537 O O . MET A 1 195 ? -5.263 17.843 22.942 1.00 17.94 ? 248 MET A O 1 ATOM 1538 C CB . MET A 1 195 ? -3.908 20.304 21.175 1.00 18.44 ? 248 MET A CB 1 ATOM 1539 C CG . MET A 1 195 ? -4.250 21.165 20.001 1.00 22.57 ? 248 MET A CG 1 ATOM 1540 S SD . MET A 1 195 ? -2.802 21.418 18.965 1.00 21.51 ? 248 MET A SD 1 ATOM 1541 C CE . MET A 1 195 ? -3.598 21.758 17.387 1.00 27.68 ? 248 MET A CE 1 ATOM 1542 N N . ILE A 1 196 ? -3.562 19.082 23.724 1.00 25.41 ? 249 ILE A N 1 ATOM 1543 C CA . ILE A 1 196 ? -2.952 17.981 24.435 1.00 27.92 ? 249 ILE A CA 1 ATOM 1544 C C . ILE A 1 196 ? -3.953 17.444 25.438 1.00 27.76 ? 249 ILE A C 1 ATOM 1545 O O . ILE A 1 196 ? -4.159 16.239 25.543 1.00 28.88 ? 249 ILE A O 1 ATOM 1546 C CB . ILE A 1 196 ? -1.676 18.437 25.136 1.00 28.77 ? 249 ILE A CB 1 ATOM 1547 C CG1 . ILE A 1 196 ? -0.546 18.573 24.117 1.00 30.26 ? 249 ILE A CG1 1 ATOM 1548 C CG2 . ILE A 1 196 ? -1.269 17.421 26.187 1.00 32.19 ? 249 ILE A CG2 1 ATOM 1549 C CD1 . ILE A 1 196 ? 0.718 19.136 24.684 1.00 30.64 ? 249 ILE A CD1 1 ATOM 1550 N N . SER A 1 197 ? -4.586 18.350 26.165 1.00 28.25 ? 250 SER A N 1 ATOM 1551 C CA . SER A 1 197 ? -5.464 17.951 27.242 1.00 28.79 ? 250 SER A CA 1 ATOM 1552 C C . SER A 1 197 ? -6.667 17.175 26.699 1.00 29.71 ? 250 SER A C 1 ATOM 1553 O O . SER A 1 197 ? -7.115 16.200 27.305 1.00 26.70 ? 250 SER A O 1 ATOM 1554 C CB . SER A 1 197 ? -5.909 19.180 28.020 1.00 29.87 ? 250 SER A CB 1 ATOM 1555 O OG . SER A 1 197 ? -4.919 19.551 28.960 1.00 31.43 ? 250 SER A OG 1 ATOM 1556 N N . VAL A 1 198 ? -7.191 17.603 25.554 1.00 28.58 ? 251 VAL A N 1 ATOM 1557 C CA . VAL A 1 198 ? -8.408 16.995 25.031 1.00 27.98 ? 251 VAL A CA 1 ATOM 1558 C C . VAL A 1 198 ? -8.081 15.585 24.547 1.00 28.84 ? 251 VAL A C 1 ATOM 1559 O O . VAL A 1 198 ? -8.847 14.647 24.752 1.00 27.26 ? 251 VAL A O 1 ATOM 1560 C CB . VAL A 1 198 ? -9.029 17.834 23.885 1.00 27.57 ? 251 VAL A CB 1 ATOM 1561 C CG1 . VAL A 1 198 ? -10.085 17.026 23.129 1.00 26.74 ? 251 VAL A CG1 1 ATOM 1562 C CG2 . VAL A 1 198 ? -9.632 19.138 24.434 1.00 26.05 ? 251 VAL A CG2 1 ATOM 1563 N N . ALA A 1 199 ? -6.923 15.442 23.917 1.00 28.97 ? 252 ALA A N 1 ATOM 1564 C CA . ALA A 1 199 ? -6.512 14.161 23.376 1.00 28.83 ? 252 ALA A CA 1 ATOM 1565 C C . ALA A 1 199 ? -6.177 13.168 24.484 1.00 30.34 ? 252 ALA A C 1 ATOM 1566 O O . ALA A 1 199 ? -6.342 11.961 24.309 1.00 30.48 ? 252 ALA A O 1 ATOM 1567 C CB . ALA A 1 199 ? -5.332 14.344 22.451 1.00 29.95 ? 252 ALA A CB 1 ATOM 1568 N N . ARG A 1 200 ? -5.729 13.667 25.633 1.00 31.75 ? 253 ARG A N 1 ATOM 1569 C CA . ARG A 1 200 ? -5.497 12.799 26.784 1.00 31.58 ? 253 ARG A CA 1 ATOM 1570 C C . ARG A 1 200 ? -6.791 12.279 27.382 1.00 32.00 ? 253 ARG A C 1 ATOM 1571 O O . ARG A 1 200 ? -6.888 11.101 27.730 1.00 32.51 ? 253 ARG A O 1 ATOM 1572 C CB . ARG A 1 200 ? -4.686 13.511 27.863 1.00 31.48 ? 253 ARG A CB 1 ATOM 1573 C CG . ARG A 1 200 ? -3.832 12.567 28.698 1.00 32.71 ? 253 ARG A CG 1 ATOM 1574 C CD . ARG A 1 200 ? -2.835 13.286 29.573 1.00 33.99 ? 253 ARG A CD 1 ATOM 1575 N NE . ARG A 1 200 ? -3.362 14.595 29.903 1.00 36.24 ? 253 ARG A NE 1 ATOM 1576 C CZ . ARG A 1 200 ? -2.693 15.724 29.800 1.00 36.06 ? 253 ARG A CZ 1 ATOM 1577 N NH1 . ARG A 1 200 ? -1.436 15.726 29.391 1.00 38.03 ? 253 ARG A NH1 1 ATOM 1578 N NH2 . ARG A 1 200 ? -3.289 16.860 30.114 1.00 38.22 ? 253 ARG A NH2 1 ATOM 1579 N N . LEU A 1 201 ? -7.789 13.145 27.504 1.00 31.94 ? 254 LEU A N 1 ATOM 1580 C CA . LEU A 1 201 ? -9.076 12.706 28.040 1.00 33.01 ? 254 LEU A CA 1 ATOM 1581 C C . LEU A 1 201 ? -9.626 11.581 27.173 1.00 33.17 ? 254 LEU A C 1 ATOM 1582 O O . LEU A 1 201 ? -10.036 10.538 27.672 1.00 35.72 ? 254 LEU A O 1 ATOM 1583 C CB . LEU A 1 201 ? -10.067 13.871 28.124 1.00 32.15 ? 254 LEU A CB 1 ATOM 1584 C CG . LEU A 1 201 ? -9.584 15.048 28.976 1.00 33.02 ? 254 LEU A CG 1 ATOM 1585 C CD1 . LEU A 1 201 ? -10.592 16.171 28.947 1.00 33.41 ? 254 LEU A CD1 1 ATOM 1586 C CD2 . LEU A 1 201 ? -9.323 14.614 30.406 1.00 33.10 ? 254 LEU A CD2 1 ATOM 1587 N N . ILE A 1 202 ? -9.609 11.776 25.865 1.00 32.97 ? 255 ILE A N 1 ATOM 1588 C CA . ILE A 1 202 ? -10.183 10.783 24.974 1.00 33.82 ? 255 ILE A CA 1 ATOM 1589 C C . ILE A 1 202 ? -9.445 9.447 25.091 1.00 35.17 ? 255 ILE A C 1 ATOM 1590 O O . ILE A 1 202 ? -10.077 8.400 25.213 1.00 37.31 ? 255 ILE A O 1 ATOM 1591 C CB . ILE A 1 202 ? -10.184 11.302 23.539 1.00 34.19 ? 255 ILE A CB 1 ATOM 1592 C CG1 . ILE A 1 202 ? -11.133 12.502 23.438 1.00 32.66 ? 255 ILE A CG1 1 ATOM 1593 C CG2 . ILE A 1 202 ? -10.589 10.184 22.567 1.00 33.84 ? 255 ILE A CG2 1 ATOM 1594 C CD1 . ILE A 1 202 ? -10.661 13.563 22.491 1.00 32.91 ? 255 ILE A CD1 1 ATOM 1595 N N . ARG A 1 203 ? -8.117 9.478 25.078 1.00 34.67 ? 256 ARG A N 1 ATOM 1596 C CA . ARG A 1 203 ? -7.343 8.248 25.200 1.00 35.72 ? 256 ARG A CA 1 ATOM 1597 C C . ARG A 1 203 ? -7.702 7.564 26.508 1.00 37.40 ? 256 ARG A C 1 ATOM 1598 O O . ARG A 1 203 ? -7.927 6.356 26.540 1.00 36.03 ? 256 ARG A O 1 ATOM 1599 C CB . ARG A 1 203 ? -5.836 8.517 25.125 1.00 34.42 ? 256 ARG A CB 1 ATOM 1600 C CG . ARG A 1 203 ? -5.368 9.066 23.782 1.00 34.30 ? 256 ARG A CG 1 ATOM 1601 C CD . ARG A 1 203 ? -3.881 8.870 23.503 1.00 37.07 ? 256 ARG A CD 1 ATOM 1602 N NE . ARG A 1 203 ? -3.628 7.896 22.438 1.00 37.62 ? 256 ARG A NE 1 ATOM 1603 C CZ . ARG A 1 203 ? -2.861 6.833 22.586 1.00 39.47 ? 256 ARG A CZ 1 ATOM 1604 N NH1 . ARG A 1 203 ? -2.266 6.601 23.749 1.00 41.32 ? 256 ARG A NH1 1 ATOM 1605 N NH2 . ARG A 1 203 ? -2.685 5.995 21.578 1.00 41.05 ? 256 ARG A NH2 1 ATOM 1606 N N . GLN A 1 204 ? -7.796 8.353 27.578 1.00 39.46 ? 257 GLN A N 1 ATOM 1607 C CA . GLN A 1 204 ? -8.193 7.827 28.880 1.00 38.15 ? 257 GLN A CA 1 ATOM 1608 C C . GLN A 1 204 ? -9.564 7.179 28.823 1.00 37.66 ? 257 GLN A C 1 ATOM 1609 O O . GLN A 1 204 ? -9.752 6.073 29.325 1.00 38.37 ? 257 GLN A O 1 ATOM 1610 C CB . GLN A 1 204 ? -8.189 8.934 29.929 1.00 38.53 ? 257 GLN A CB 1 ATOM 1611 C CG . GLN A 1 204 ? -6.888 9.706 29.972 1.00 38.81 ? 257 GLN A CG 1 ATOM 1612 C CD . GLN A 1 204 ? -6.730 10.530 31.239 1.00 39.91 ? 257 GLN A CD 1 ATOM 1613 O OE1 . GLN A 1 204 ? -5.785 10.320 31.998 1.00 40.82 ? 257 GLN A OE1 1 ATOM 1614 N NE2 . GLN A 1 204 ? -7.642 11.475 31.462 1.00 37.96 ? 257 GLN A NE2 1 ATOM 1615 N N . GLU A 1 205 ? -10.524 7.867 28.216 1.00 36.66 ? 258 GLU A N 1 ATOM 1616 C CA . GLU A 1 205 ? -11.899 7.385 28.201 1.00 35.63 ? 258 GLU A CA 1 ATOM 1617 C C . GLU A 1 205 ? -11.991 6.164 27.305 1.00 37.38 ? 258 GLU A C 1 ATOM 1618 O O . GLU A 1 205 ? -12.841 5.300 27.504 1.00 33.93 ? 258 GLU A O 1 ATOM 1619 C CB . GLU A 1 205 ? -12.860 8.471 27.709 1.00 35.86 ? 258 GLU A CB 1 ATOM 1620 C CG . GLU A 1 205 ? -14.228 8.433 28.378 1.00 34.73 ? 258 GLU A CG 1 ATOM 1621 C CD . GLU A 1 205 ? -15.114 9.595 27.979 1.00 35.82 ? 258 GLU A CD 1 ATOM 1622 O OE1 . GLU A 1 205 ? -14.604 10.559 27.382 1.00 36.77 ? 258 GLU A OE1 1 ATOM 1623 O OE2 . GLU A 1 205 ? -16.330 9.547 28.253 1.00 38.23 ? 258 GLU A OE2 1 ATOM 1624 N N . GLU A 1 206 ? -11.109 6.103 26.313 1.00 39.45 ? 259 GLU A N 1 ATOM 1625 C CA . GLU A 1 206 ? -11.040 4.953 25.427 1.00 41.47 ? 259 GLU A CA 1 ATOM 1626 C C . GLU A 1 206 ? -10.301 3.818 26.114 1.00 43.14 ? 259 GLU A C 1 ATOM 1627 O O . GLU A 1 206 ? -10.162 2.731 25.556 1.00 44.74 ? 259 GLU A O 1 ATOM 1628 C CB . GLU A 1 206 ? -10.331 5.321 24.127 1.00 41.81 ? 259 GLU A CB 1 ATOM 1629 C CG . GLU A 1 206 ? -11.253 5.877 23.057 1.00 43.25 ? 259 GLU A CG 1 ATOM 1630 C CD . GLU A 1 206 ? -12.431 4.966 22.775 1.00 45.01 ? 259 GLU A CD 1 ATOM 1631 O OE1 . GLU A 1 206 ? -13.020 5.058 21.677 1.00 44.30 ? 259 GLU A OE1 1 ATOM 1632 O OE2 . GLU A 1 206 ? -12.771 4.153 23.659 1.00 50.47 ? 259 GLU A OE2 1 ATOM 1633 N N . ARG A 1 207 ? -9.827 4.078 27.327 1.00 43.15 ? 260 ARG A N 1 ATOM 1634 C CA . ARG A 1 207 ? -8.645 3.409 27.837 1.00 46.17 ? 260 ARG A CA 1 ATOM 1635 C C . ARG A 1 207 ? -7.693 3.120 26.687 1.00 45.52 ? 260 ARG A C 1 ATOM 1636 O O . ARG A 1 207 ? -7.647 2.005 26.174 1.00 48.11 ? 260 ARG A O 1 ATOM 1637 C CB . ARG A 1 207 ? -9.033 2.101 28.539 1.00 48.70 ? 260 ARG A CB 1 ATOM 1638 C CG . ARG A 1 207 ? -9.110 2.197 30.063 1.00 50.21 ? 260 ARG A CG 1 ATOM 1639 C CD . ARG A 1 207 ? -10.288 3.011 30.575 1.00 53.17 ? 260 ARG A CD 1 ATOM 1640 N NE . ARG A 1 207 ? -11.355 2.175 31.126 1.00 55.54 ? 260 ARG A NE 1 ATOM 1641 C CZ . ARG A 1 207 ? -12.122 1.367 30.403 1.00 56.05 ? 260 ARG A CZ 1 ATOM 1642 N NH1 . ARG A 1 207 ? -11.944 1.271 29.093 1.00 54.79 ? 260 ARG A NH1 1 ATOM 1643 N NH2 . ARG A 1 207 ? -13.069 0.651 30.990 1.00 57.12 ? 260 ARG A NH2 1 ATOM 1644 N N . LEU A 1 208 ? -6.944 4.133 26.273 1.00 43.81 ? 261 LEU A N 1 ATOM 1645 C CA . LEU A 1 208 ? -5.703 3.917 25.550 1.00 43.37 ? 261 LEU A CA 1 ATOM 1646 C C . LEU A 1 208 ? -4.526 4.336 26.421 1.00 42.38 ? 261 LEU A C 1 ATOM 1647 O O . LEU A 1 208 ? -4.681 5.098 27.378 1.00 40.86 ? 261 LEU A O 1 ATOM 1648 C CB . LEU A 1 208 ? -5.704 4.698 24.235 1.00 43.60 ? 261 LEU A CB 1 ATOM 1649 C CG . LEU A 1 208 ? -6.931 4.442 23.354 1.00 44.76 ? 261 LEU A CG 1 ATOM 1650 C CD1 . LEU A 1 208 ? -6.664 4.790 21.896 1.00 44.21 ? 261 LEU A CD1 1 ATOM 1651 C CD2 . LEU A 1 208 ? -7.388 2.993 23.480 1.00 45.70 ? 261 LEU A CD2 1 ATOM 1652 N N . PRO A 1 209 ? -3.352 3.812 26.103 1.00 41.82 ? 262 PRO A N 1 ATOM 1653 C CA . PRO A 1 209 ? -2.129 4.181 26.822 1.00 41.98 ? 262 PRO A CA 1 ATOM 1654 C C . PRO A 1 209 ? -1.648 5.580 26.451 1.00 39.66 ? 262 PRO A C 1 ATOM 1655 O O . PRO A 1 209 ? -1.826 6.038 25.323 1.00 34.39 ? 262 PRO A O 1 ATOM 1656 C CB . PRO A 1 209 ? -1.118 3.112 26.389 1.00 42.06 ? 262 PRO A CB 1 ATOM 1657 C CG . PRO A 1 209 ? -1.620 2.602 25.076 1.00 43.20 ? 262 PRO A CG 1 ATOM 1658 C CD . PRO A 1 209 ? -3.112 2.818 25.045 1.00 42.60 ? 262 PRO A CD 1 ATOM 1659 N N . ILE A 1 210 ? -1.054 6.261 27.419 1.00 38.32 ? 263 ILE A N 1 ATOM 1660 C CA . ILE A 1 210 ? -0.816 7.682 27.287 1.00 38.86 ? 263 ILE A CA 1 ATOM 1661 C C . ILE A 1 210 ? 0.669 7.973 27.423 1.00 40.37 ? 263 ILE A C 1 ATOM 1662 O O . ILE A 1 210 ? 1.285 7.719 28.464 1.00 41.86 ? 263 ILE A O 1 ATOM 1663 C CB . ILE A 1 210 ? -1.632 8.470 28.331 1.00 36.61 ? 263 ILE A CB 1 ATOM 1664 C CG1 . ILE A 1 210 ? -2.759 9.232 27.640 1.00 34.52 ? 263 ILE A CG1 1 ATOM 1665 C CG2 . ILE A 1 210 ? -0.741 9.434 29.081 1.00 36.09 ? 263 ILE A CG2 1 ATOM 1666 C CD1 . ILE A 1 210 ? -4.074 8.506 27.657 1.00 33.51 ? 263 ILE A CD1 1 ATOM 1667 N N . ASP A 1 211 ? 1.233 8.501 26.345 1.00 40.82 ? 264 ASP A N 1 ATOM 1668 C CA . ASP A 1 211 ? 2.643 8.831 26.291 1.00 40.48 ? 264 ASP A CA 1 ATOM 1669 C C . ASP A 1 211 ? 2.785 10.320 26.033 1.00 39.32 ? 264 ASP A C 1 ATOM 1670 O O . ASP A 1 211 ? 2.674 10.781 24.896 1.00 39.63 ? 264 ASP A O 1 ATOM 1671 C CB . ASP A 1 211 ? 3.318 8.029 25.182 1.00 42.05 ? 264 ASP A CB 1 ATOM 1672 C CG . ASP A 1 211 ? 4.698 8.532 24.865 1.00 42.72 ? 264 ASP A CG 1 ATOM 1673 O OD1 . ASP A 1 211 ? 5.303 9.182 25.740 1.00 44.81 ? 264 ASP A OD1 1 ATOM 1674 O OD2 . ASP A 1 211 ? 5.251 8.333 23.764 1.00 43.65 ? 264 ASP A OD2 1 ATOM 1675 N N . GLU A 1 212 ? 3.009 11.075 27.102 1.00 40.72 ? 265 GLU A N 1 ATOM 1676 C CA . GLU A 1 212 ? 2.941 12.530 27.046 1.00 39.28 ? 265 GLU A CA 1 ATOM 1677 C C . GLU A 1 212 ? 3.790 13.053 25.897 1.00 40.01 ? 265 GLU A C 1 ATOM 1678 O O . GLU A 1 212 ? 3.380 13.964 25.175 1.00 40.21 ? 265 GLU A O 1 ATOM 1679 C CB . GLU A 1 212 ? 3.396 13.128 28.373 1.00 37.79 ? 265 GLU A CB 1 ATOM 1680 C CG . GLU A 1 212 ? 2.486 12.758 29.537 1.00 37.27 ? 265 GLU A CG 1 ATOM 1681 C CD . GLU A 1 212 ? 1.122 13.423 29.434 1.00 35.74 ? 265 GLU A CD 1 ATOM 1682 O OE1 . GLU A 1 212 ? 0.275 13.243 30.342 1.00 33.34 ? 265 GLU A OE1 1 ATOM 1683 O OE2 . GLU A 1 212 ? 0.906 14.137 28.439 1.00 32.28 ? 265 GLU A OE2 1 ATOM 1684 N N . ASN A 1 213 ? 4.961 12.458 25.716 1.00 38.95 ? 266 ASN A N 1 ATOM 1685 C CA . ASN A 1 213 ? 5.936 13.007 24.791 1.00 40.34 ? 266 ASN A CA 1 ATOM 1686 C C . ASN A 1 213 ? 5.414 12.959 23.370 1.00 38.06 ? 266 ASN A C 1 ATOM 1687 O O . ASN A 1 213 ? 5.594 13.906 22.588 1.00 34.83 ? 266 ASN A O 1 ATOM 1688 C CB . ASN A 1 213 ? 7.267 12.260 24.895 1.00 42.44 ? 266 ASN A CB 1 ATOM 1689 C CG . ASN A 1 213 ? 8.413 13.184 25.224 1.00 44.31 ? 266 ASN A CG 1 ATOM 1690 O OD1 . ASN A 1 213 ? 9.396 13.267 24.481 1.00 48.07 ? 266 ASN A OD1 1 ATOM 1691 N ND2 . ASN A 1 213 ? 8.285 13.910 26.330 1.00 43.82 ? 266 ASN A ND2 1 ATOM 1692 N N . GLN A 1 214 ? 4.744 11.859 23.047 1.00 36.63 ? 267 GLN A N 1 ATOM 1693 C CA . GLN A 1 214 ? 4.187 11.673 21.713 1.00 35.48 ? 267 GLN A CA 1 ATOM 1694 C C . GLN A 1 214 ? 2.960 12.560 21.500 1.00 32.86 ? 267 GLN A C 1 ATOM 1695 O O . GLN A 1 214 ? 2.706 13.015 20.389 1.00 31.54 ? 267 GLN A O 1 ATOM 1696 C CB . GLN A 1 214 ? 3.817 10.206 21.493 1.00 36.37 ? 267 GLN A CB 1 ATOM 1697 C CG . GLN A 1 214 ? 3.329 9.898 20.093 1.00 37.26 ? 267 GLN A CG 1 ATOM 1698 C CD . GLN A 1 214 ? 4.461 9.746 19.102 1.00 37.78 ? 267 GLN A CD 1 ATOM 1699 O OE1 . GLN A 1 214 ? 4.230 9.716 17.893 1.00 39.38 ? 267 GLN A OE1 1 ATOM 1700 N NE2 . GLN A 1 214 ? 5.685 9.649 19.606 1.00 38.55 ? 267 GLN A NE2 1 ATOM 1701 N N . LEU A 1 215 ? 2.204 12.806 22.566 1.00 33.57 ? 268 LEU A N 1 ATOM 1702 C CA . LEU A 1 215 ? 1.116 13.782 22.519 1.00 34.39 ? 268 LEU A CA 1 ATOM 1703 C C . LEU A 1 215 ? 1.657 15.161 22.149 1.00 32.24 ? 268 LEU A C 1 ATOM 1704 O O . LEU A 1 215 ? 1.213 15.778 21.183 1.00 30.84 ? 268 LEU A O 1 ATOM 1705 C CB . LEU A 1 215 ? 0.400 13.866 23.864 1.00 33.74 ? 268 LEU A CB 1 ATOM 1706 C CG . LEU A 1 215 ? -0.514 12.719 24.305 1.00 32.58 ? 268 LEU A CG 1 ATOM 1707 C CD1 . LEU A 1 215 ? -1.135 13.093 25.623 1.00 32.65 ? 268 LEU A CD1 1 ATOM 1708 C CD2 . LEU A 1 215 ? -1.585 12.404 23.294 1.00 33.02 ? 268 LEU A CD2 1 ATOM 1709 N N . ALA A 1 216 ? 2.625 15.632 22.922 1.00 30.96 ? 269 ALA A N 1 ATOM 1710 C CA . ALA A 1 216 ? 3.298 16.883 22.618 1.00 31.86 ? 269 ALA A CA 1 ATOM 1711 C C . ALA A 1 216 ? 3.897 16.807 21.230 1.00 33.26 ? 269 ALA A C 1 ATOM 1712 O O . ALA A 1 216 ? 3.839 17.763 20.464 1.00 33.13 ? 269 ALA A O 1 ATOM 1713 C CB . ALA A 1 216 ? 4.377 17.160 23.646 1.00 31.99 ? 269 ALA A CB 1 ATOM 1714 N N . LEU A 1 217 ? 4.470 15.653 20.913 1.00 35.75 ? 270 LEU A N 1 ATOM 1715 C CA . LEU A 1 217 ? 5.054 15.431 19.604 1.00 37.49 ? 270 LEU A CA 1 ATOM 1716 C C . LEU A 1 217 ? 4.064 15.826 18.532 1.00 35.16 ? 270 LEU A C 1 ATOM 1717 O O . LEU A 1 217 ? 4.378 16.614 17.641 1.00 37.56 ? 270 LEU A O 1 ATOM 1718 C CB . LEU A 1 217 ? 5.451 13.962 19.433 1.00 41.32 ? 270 LEU A CB 1 ATOM 1719 C CG . LEU A 1 217 ? 6.372 13.704 18.240 1.00 42.97 ? 270 LEU A CG 1 ATOM 1720 C CD1 . LEU A 1 217 ? 7.417 14.804 18.130 1.00 43.33 ? 270 LEU A CD1 1 ATOM 1721 C CD2 . LEU A 1 217 ? 7.038 12.348 18.351 1.00 42.52 ? 270 LEU A CD2 1 ATOM 1722 N N . GLU A 1 218 ? 2.858 15.274 18.626 1.00 33.49 ? 271 GLU A N 1 ATOM 1723 C CA . GLU A 1 218 ? 1.899 15.327 17.526 1.00 29.80 ? 271 GLU A CA 1 ATOM 1724 C C . GLU A 1 218 ? 1.134 16.650 17.531 1.00 27.16 ? 271 GLU A C 1 ATOM 1725 O O . GLU A 1 218 ? 0.837 17.211 16.477 1.00 22.09 ? 271 GLU A O 1 ATOM 1726 C CB . GLU A 1 218 ? 0.915 14.151 17.607 1.00 31.29 ? 271 GLU A CB 1 ATOM 1727 C CG . GLU A 1 218 ? 1.303 12.958 16.742 1.00 32.68 ? 271 GLU A CG 1 ATOM 1728 C CD . GLU A 1 218 ? 0.225 11.890 16.690 1.00 32.95 ? 271 GLU A CD 1 ATOM 1729 O OE1 . GLU A 1 218 ? -0.688 11.993 15.838 1.00 29.31 ? 271 GLU A OE1 1 ATOM 1730 O OE2 . GLU A 1 218 ? 0.293 10.947 17.505 1.00 35.70 ? 271 GLU A OE2 1 ATOM 1731 N N . MET A 1 219 ? 0.835 17.159 18.719 1.00 26.72 ? 272 MET A N 1 ATOM 1732 C CA . MET A 1 219 ? 0.121 18.423 18.825 1.00 28.36 ? 272 MET A CA 1 ATOM 1733 C C . MET A 1 219 ? 1.009 19.619 18.461 1.00 29.09 ? 272 MET A C 1 ATOM 1734 O O . MET A 1 219 ? 0.528 20.636 17.974 1.00 29.70 ? 272 MET A O 1 ATOM 1735 C CB . MET A 1 219 ? -0.460 18.591 20.229 1.00 28.15 ? 272 MET A CB 1 ATOM 1736 C CG . MET A 1 219 ? -1.644 17.681 20.517 1.00 29.06 ? 272 MET A CG 1 ATOM 1737 S SD . MET A 1 219 ? -2.797 17.537 19.109 1.00 28.66 ? 272 MET A SD 1 ATOM 1738 C CE . MET A 1 219 ? -1.961 16.324 18.080 1.00 28.16 ? 272 MET A CE 1 ATOM 1739 N N . ASN A 1 220 ? 2.307 19.511 18.678 1.00 30.90 ? 273 ASN A N 1 ATOM 1740 C CA . ASN A 1 220 ? 3.189 20.581 18.229 1.00 33.50 ? 273 ASN A CA 1 ATOM 1741 C C . ASN A 1 220 ? 3.231 20.589 16.707 1.00 33.17 ? 273 ASN A C 1 ATOM 1742 O O . ASN A 1 220 ? 3.246 21.645 16.080 1.00 33.48 ? 273 ASN A O 1 ATOM 1743 C CB . ASN A 1 220 ? 4.591 20.448 18.838 1.00 33.17 ? 273 ASN A CB 1 ATOM 1744 C CG . ASN A 1 220 ? 4.671 21.052 20.233 1.00 34.27 ? 273 ASN A CG 1 ATOM 1745 O OD1 . ASN A 1 220 ? 4.234 22.183 20.458 1.00 32.49 ? 273 ASN A OD1 1 ATOM 1746 N ND2 . ASN A 1 220 ? 5.225 20.298 21.175 1.00 33.78 ? 273 ASN A ND2 1 ATOM 1747 N N . LYS A 1 221 ? 3.222 19.394 16.125 1.00 33.55 ? 274 LYS A N 1 ATOM 1748 C CA . LYS A 1 221 ? 3.220 19.230 14.682 1.00 31.78 ? 274 LYS A CA 1 ATOM 1749 C C . LYS A 1 221 ? 1.965 19.840 14.068 1.00 30.34 ? 274 LYS A C 1 ATOM 1750 O O . LYS A 1 221 ? 2.026 20.456 13.004 1.00 30.05 ? 274 LYS A O 1 ATOM 1751 C CB . LYS A 1 221 ? 3.311 17.742 14.335 1.00 34.29 ? 274 LYS A CB 1 ATOM 1752 C CG . LYS A 1 221 ? 3.868 17.449 12.948 1.00 36.37 ? 274 LYS A CG 1 ATOM 1753 C CD . LYS A 1 221 ? 5.404 17.425 12.948 1.00 38.36 ? 274 LYS A CD 1 ATOM 1754 C CE . LYS A 1 221 ? 5.966 17.965 11.641 1.00 40.61 ? 274 LYS A CE 1 ATOM 1755 N NZ . LYS A 1 221 ? 7.381 18.447 11.769 1.00 42.62 ? 274 LYS A NZ 1 ATOM 1756 N N . VAL A 1 222 ? 0.828 19.679 14.743 1.00 27.39 ? 275 VAL A N 1 ATOM 1757 C CA . VAL A 1 222 ? -0.410 20.324 14.308 1.00 26.20 ? 275 VAL A CA 1 ATOM 1758 C C . VAL A 1 222 ? -0.297 21.845 14.312 1.00 24.49 ? 275 VAL A C 1 ATOM 1759 O O . VAL A 1 222 ? -0.773 22.512 13.385 1.00 28.82 ? 275 VAL A O 1 ATOM 1760 C CB . VAL A 1 222 ? -1.608 19.923 15.181 1.00 25.01 ? 275 VAL A CB 1 ATOM 1761 C CG1 . VAL A 1 222 ? -2.805 20.807 14.866 1.00 24.39 ? 275 VAL A CG1 1 ATOM 1762 C CG2 . VAL A 1 222 ? -1.942 18.461 14.974 1.00 26.23 ? 275 VAL A CG2 1 ATOM 1763 N N . MET A 1 223 ? 0.334 22.383 15.348 1.00 24.75 ? 276 MET A N 1 ATOM 1764 C CA . MET A 1 223 ? 0.549 23.825 15.473 1.00 26.04 ? 276 MET A CA 1 ATOM 1765 C C . MET A 1 223 ? 1.437 24.379 14.359 1.00 28.35 ? 276 MET A C 1 ATOM 1766 O O . MET A 1 223 ? 1.180 25.465 13.832 1.00 26.31 ? 276 MET A O 1 ATOM 1767 C CB . MET A 1 223 ? 1.168 24.145 16.835 1.00 28.51 ? 276 MET A CB 1 ATOM 1768 C CG . MET A 1 223 ? 1.382 25.627 17.083 1.00 30.03 ? 276 MET A CG 1 ATOM 1769 S SD . MET A 1 223 ? -0.132 26.565 16.804 1.00 31.06 ? 276 MET A SD 1 ATOM 1770 C CE . MET A 1 223 ? 0.042 27.883 17.995 1.00 29.53 ? 276 MET A CE 1 ATOM 1771 N N . GLU A 1 224 ? 2.490 23.649 13.994 1.00 29.63 ? 277 GLU A N 1 ATOM 1772 C CA . GLU A 1 224 ? 3.424 24.186 13.014 1.00 31.51 ? 277 GLU A CA 1 ATOM 1773 C C . GLU A 1 224 ? 2.790 24.122 11.630 1.00 28.35 ? 277 GLU A C 1 ATOM 1774 O O . GLU A 1 224 ? 3.032 24.983 10.790 1.00 28.40 ? 277 GLU A O 1 ATOM 1775 C CB . GLU A 1 224 ? 4.776 23.461 13.055 1.00 35.18 ? 277 GLU A CB 1 ATOM 1776 C CG . GLU A 1 224 ? 5.813 24.003 12.069 1.00 39.56 ? 277 GLU A CG 1 ATOM 1777 C CD . GLU A 1 224 ? 6.155 25.488 12.268 1.00 41.47 ? 277 GLU A CD 1 ATOM 1778 O OE1 . GLU A 1 224 ? 5.585 26.339 11.545 1.00 37.80 ? 277 GLU A OE1 1 ATOM 1779 O OE2 . GLU A 1 224 ? 7.014 25.808 13.130 1.00 43.51 ? 277 GLU A OE2 1 ATOM 1780 N N . LEU A 1 225 ? 1.945 23.119 11.410 1.00 27.15 ? 278 LEU A N 1 ATOM 1781 C CA . LEU A 1 225 ? 1.046 23.117 10.261 1.00 23.39 ? 278 LEU A CA 1 ATOM 1782 C C . LEU A 1 225 ? 0.187 24.367 10.240 1.00 23.40 ? 278 LEU A C 1 ATOM 1783 O O . LEU A 1 225 ? 0.079 25.030 9.214 1.00 21.57 ? 278 LEU A O 1 ATOM 1784 C CB . LEU A 1 225 ? 0.133 21.898 10.307 1.00 23.43 ? 278 LEU A CB 1 ATOM 1785 C CG . LEU A 1 225 ? -0.226 21.170 9.011 1.00 23.33 ? 278 LEU A CG 1 ATOM 1786 C CD1 . LEU A 1 225 ? -1.586 20.512 9.158 1.00 20.93 ? 278 LEU A CD1 1 ATOM 1787 C CD2 . LEU A 1 225 ? -0.199 22.089 7.783 1.00 26.15 ? 278 LEU A CD2 1 ATOM 1788 N N . GLU A 1 226 ? -0.459 24.684 11.360 1.00 25.31 ? 279 GLU A N 1 ATOM 1789 C CA . GLU A 1 226 ? -1.433 25.764 11.330 1.00 25.44 ? 279 GLU A CA 1 ATOM 1790 C C . GLU A 1 226 ? -0.687 27.076 11.201 1.00 24.32 ? 279 GLU A C 1 ATOM 1791 O O . GLU A 1 226 ? -1.158 27.995 10.537 1.00 24.14 ? 279 GLU A O 1 ATOM 1792 C CB . GLU A 1 226 ? -2.365 25.769 12.547 1.00 25.94 ? 279 GLU A CB 1 ATOM 1793 C CG . GLU A 1 226 ? -3.694 26.473 12.251 1.00 25.46 ? 279 GLU A CG 1 ATOM 1794 C CD . GLU A 1 226 ? -4.670 26.494 13.422 1.00 26.66 ? 279 GLU A CD 1 ATOM 1795 O OE1 . GLU A 1 226 ? -4.228 26.392 14.585 1.00 29.67 ? 279 GLU A OE1 1 ATOM 1796 O OE2 . GLU A 1 226 ? -5.897 26.604 13.181 1.00 26.92 ? 279 GLU A OE2 1 ATOM 1797 N N . LYS A 1 227 ? 0.489 27.148 11.814 1.00 24.48 ? 280 LYS A N 1 ATOM 1798 C CA . LYS A 1 227 ? 1.356 28.300 11.650 1.00 25.23 ? 280 LYS A CA 1 ATOM 1799 C C . LYS A 1 227 ? 1.538 28.627 10.173 1.00 24.85 ? 280 LYS A C 1 ATOM 1800 O O . LYS A 1 227 ? 1.318 29.762 9.749 1.00 25.53 ? 280 LYS A O 1 ATOM 1801 C CB . LYS A 1 227 ? 2.712 28.053 12.324 1.00 27.85 ? 280 LYS A CB 1 ATOM 1802 C CG . LYS A 1 227 ? 2.811 28.670 13.738 1.00 29.27 ? 280 LYS A CG 1 ATOM 1803 C CD . LYS A 1 227 ? 4.183 28.473 14.377 1.00 28.55 ? 280 LYS A CD 1 ATOM 1804 C CE . LYS A 1 227 ? 4.115 28.554 15.897 1.00 29.10 ? 280 LYS A CE 1 ATOM 1805 N NZ . LYS A 1 227 ? 5.465 28.402 16.537 1.00 29.73 ? 280 LYS A NZ 1 ATOM 1806 N N . GLU A 1 228 ? 1.925 27.623 9.393 1.00 25.40 ? 281 GLU A N 1 ATOM 1807 C CA . GLU A 1 228 ? 2.131 27.792 7.962 1.00 24.92 ? 281 GLU A CA 1 ATOM 1808 C C . GLU A 1 228 ? 0.856 28.218 7.233 1.00 25.64 ? 281 GLU A C 1 ATOM 1809 O O . GLU A 1 228 ? 0.878 29.165 6.443 1.00 24.68 ? 281 GLU A O 1 ATOM 1810 C CB . GLU A 1 228 ? 2.684 26.510 7.356 1.00 25.43 ? 281 GLU A CB 1 ATOM 1811 C CG . GLU A 1 228 ? 4.089 26.196 7.832 1.00 29.18 ? 281 GLU A CG 1 ATOM 1812 C CD . GLU A 1 228 ? 4.783 25.147 6.982 1.00 29.73 ? 281 GLU A CD 1 ATOM 1813 O OE1 . GLU A 1 228 ? 4.997 24.019 7.480 1.00 33.71 ? 281 GLU A OE1 1 ATOM 1814 O OE2 . GLU A 1 228 ? 5.126 25.457 5.826 1.00 28.78 ? 281 GLU A OE2 1 ATOM 1815 N N . ILE A 1 229 ? -0.252 27.531 7.498 1.00 25.87 ? 282 ILE A N 1 ATOM 1816 C CA . ILE A 1 229 ? -1.534 27.914 6.914 1.00 25.15 ? 282 ILE A CA 1 ATOM 1817 C C . ILE A 1 229 ? -1.866 29.350 7.300 1.00 24.86 ? 282 ILE A C 1 ATOM 1818 O O . ILE A 1 229 ? -2.417 30.115 6.505 1.00 26.25 ? 282 ILE A O 1 ATOM 1819 C CB . ILE A 1 229 ? -2.651 26.938 7.375 1.00 26.57 ? 282 ILE A CB 1 ATOM 1820 C CG1 . ILE A 1 229 ? -2.401 25.539 6.800 1.00 26.01 ? 282 ILE A CG1 1 ATOM 1821 C CG2 . ILE A 1 229 ? -4.038 27.440 6.959 1.00 24.60 ? 282 ILE A CG2 1 ATOM 1822 C CD1 . ILE A 1 229 ? -3.333 24.478 7.350 1.00 25.08 ? 282 ILE A CD1 1 ATOM 1823 N N . ALA A 1 230 ? -1.514 29.731 8.516 1.00 24.79 ? 283 ALA A N 1 ATOM 1824 C CA . ALA A 1 230 ? -1.739 31.107 8.957 1.00 27.55 ? 283 ALA A CA 1 ATOM 1825 C C . ALA A 1 230 ? -0.935 32.092 8.119 1.00 28.49 ? 283 ALA A C 1 ATOM 1826 O O . ALA A 1 230 ? -1.446 33.155 7.740 1.00 28.24 ? 283 ALA A O 1 ATOM 1827 C CB . ALA A 1 230 ? -1.402 31.265 10.439 1.00 24.68 ? 283 ALA A CB 1 ATOM 1828 N N . ASN A 1 231 ? 0.321 31.746 7.838 1.00 27.98 ? 284 ASN A N 1 ATOM 1829 C CA . ASN A 1 231 ? 1.224 32.682 7.185 1.00 25.75 ? 284 ASN A CA 1 ATOM 1830 C C . ASN A 1 231 ? 0.784 32.838 5.748 1.00 24.14 ? 284 ASN A C 1 ATOM 1831 O O . ASN A 1 231 ? 1.064 33.858 5.110 1.00 21.02 ? 284 ASN A O 1 ATOM 1832 C CB . ASN A 1 231 ? 2.675 32.201 7.253 1.00 28.98 ? 284 ASN A CB 1 ATOM 1833 C CG . ASN A 1 231 ? 3.637 33.129 6.513 1.00 31.22 ? 284 ASN A CG 1 ATOM 1834 O OD1 . ASN A 1 231 ? 4.371 32.701 5.617 1.00 33.38 ? 284 ASN A OD1 1 ATOM 1835 N ND2 . ASN A 1 231 ? 3.623 34.406 6.875 1.00 30.18 ? 284 ASN A ND2 1 ATOM 1836 N N . ALA A 1 232 ? 0.078 31.817 5.262 1.00 20.10 ? 285 ALA A N 1 ATOM 1837 C CA . ALA A 1 232 ? -0.344 31.737 3.874 1.00 19.93 ? 285 ALA A CA 1 ATOM 1838 C C . ALA A 1 232 ? -1.668 32.458 3.649 1.00 24.00 ? 285 ALA A C 1 ATOM 1839 O O . ALA A 1 232 ? -2.000 32.796 2.513 1.00 23.92 ? 285 ALA A O 1 ATOM 1840 C CB . ALA A 1 232 ? -0.478 30.284 3.456 1.00 17.86 ? 285 ALA A CB 1 ATOM 1841 N N . THR A 1 233 ? -2.440 32.681 4.713 1.00 24.29 ? 286 THR A N 1 ATOM 1842 C CA . THR A 1 233 ? -3.685 33.420 4.564 1.00 22.78 ? 286 THR A CA 1 ATOM 1843 C C . THR A 1 233 ? -3.414 34.887 4.292 1.00 22.96 ? 286 THR A C 1 ATOM 1844 O O . THR A 1 233 ? -2.496 35.468 4.843 1.00 27.06 ? 286 THR A O 1 ATOM 1845 C CB . THR A 1 233 ? -4.583 33.269 5.796 1.00 21.52 ? 286 THR A CB 1 ATOM 1846 O OG1 . THR A 1 233 ? -3.958 33.838 6.952 1.00 21.63 ? 286 THR A OG1 1 ATOM 1847 C CG2 . THR A 1 233 ? -4.762 31.830 6.153 1.00 21.13 ? 286 THR A CG2 1 ATOM 1848 N N . ALA A 1 234 ? -4.236 35.486 3.443 1.00 26.18 ? 287 ALA A N 1 ATOM 1849 C CA . ALA A 1 234 ? -4.147 36.911 3.166 1.00 24.86 ? 287 ALA A CA 1 ATOM 1850 C C . ALA A 1 234 ? -4.667 37.699 4.348 1.00 26.04 ? 287 ALA A C 1 ATOM 1851 O O . ALA A 1 234 ? -5.565 37.248 5.050 1.00 26.85 ? 287 ALA A O 1 ATOM 1852 C CB . ALA A 1 234 ? -4.934 37.256 1.912 1.00 25.69 ? 287 ALA A CB 1 ATOM 1853 N N . LYS A 1 235 ? -4.074 38.869 4.570 1.00 27.06 ? 288 LYS A N 1 ATOM 1854 C CA . LYS A 1 235 ? -4.517 39.803 5.590 1.00 26.81 ? 288 LYS A CA 1 ATOM 1855 C C . LYS A 1 235 ? -5.900 40.324 5.239 1.00 26.66 ? 288 LYS A C 1 ATOM 1856 O O . LYS A 1 235 ? -6.294 40.317 4.065 1.00 26.04 ? 288 LYS A O 1 ATOM 1857 C CB . LYS A 1 235 ? -3.546 40.982 5.670 1.00 28.49 ? 288 LYS A CB 1 ATOM 1858 C CG . LYS A 1 235 ? -2.244 40.707 6.406 1.00 31.21 ? 288 LYS A CG 1 ATOM 1859 C CD . LYS A 1 235 ? -1.214 41.817 6.151 1.00 32.78 ? 288 LYS A CD 1 ATOM 1860 C CE . LYS A 1 235 ? -0.279 42.017 7.351 1.00 34.71 ? 288 LYS A CE 1 ATOM 1861 N NZ . LYS A 1 235 ? 1.017 42.697 7.001 1.00 34.02 ? 288 LYS A NZ 1 ATOM 1862 N N . PRO A 1 236 ? -6.624 40.789 6.255 1.00 26.34 ? 289 PRO A N 1 ATOM 1863 C CA . PRO A 1 236 ? -7.857 41.572 6.068 1.00 28.92 ? 289 PRO A CA 1 ATOM 1864 C C . PRO A 1 236 ? -7.687 42.783 5.160 1.00 30.66 ? 289 PRO A C 1 ATOM 1865 O O . PRO A 1 236 ? -8.528 43.010 4.290 1.00 29.83 ? 289 PRO A O 1 ATOM 1866 C CB . PRO A 1 236 ? -8.211 42.016 7.492 1.00 27.49 ? 289 PRO A CB 1 ATOM 1867 C CG . PRO A 1 236 ? -7.592 40.966 8.369 1.00 26.68 ? 289 PRO A CG 1 ATOM 1868 C CD . PRO A 1 236 ? -6.324 40.569 7.679 1.00 27.09 ? 289 PRO A CD 1 ATOM 1869 N N . GLU A 1 237 ? -6.602 43.528 5.346 1.00 31.95 ? 290 GLU A N 1 ATOM 1870 C CA . GLU A 1 237 ? -6.369 44.758 4.595 1.00 32.34 ? 290 GLU A CA 1 ATOM 1871 C C . GLU A 1 237 ? -6.149 44.503 3.110 1.00 32.52 ? 290 GLU A C 1 ATOM 1872 O O . GLU A 1 237 ? -6.228 45.428 2.295 1.00 33.26 ? 290 GLU A O 1 ATOM 1873 C CB . GLU A 1 237 ? -5.144 45.476 5.150 1.00 33.81 ? 290 GLU A CB 1 ATOM 1874 C CG . GLU A 1 237 ? -5.258 45.820 6.618 1.00 34.67 ? 290 GLU A CG 1 ATOM 1875 C CD . GLU A 1 237 ? -4.327 44.989 7.468 1.00 35.56 ? 290 GLU A CD 1 ATOM 1876 O OE1 . GLU A 1 237 ? -3.291 45.536 7.896 1.00 38.84 ? 290 GLU A OE1 1 ATOM 1877 O OE2 . GLU A 1 237 ? -4.628 43.796 7.698 1.00 33.77 ? 290 GLU A OE2 1 ATOM 1878 N N . ASP A 1 238 ? -5.839 43.257 2.772 1.00 32.19 ? 291 ASP A N 1 ATOM 1879 C CA . ASP A 1 238 ? -5.621 42.868 1.387 1.00 33.62 ? 291 ASP A CA 1 ATOM 1880 C C . ASP A 1 238 ? -6.820 42.064 0.910 1.00 32.55 ? 291 ASP A C 1 ATOM 1881 O O . ASP A 1 238 ? -6.764 41.449 -0.156 1.00 28.08 ? 291 ASP A O 1 ATOM 1882 C CB . ASP A 1 238 ? -4.407 41.949 1.255 1.00 35.51 ? 291 ASP A CB 1 ATOM 1883 C CG . ASP A 1 238 ? -3.090 42.659 1.481 1.00 36.22 ? 291 ASP A CG 1 ATOM 1884 O OD1 . ASP A 1 238 ? -2.939 43.840 1.088 1.00 35.85 ? 291 ASP A OD1 1 ATOM 1885 O OD2 . ASP A 1 238 ? -2.139 42.070 2.038 1.00 36.04 ? 291 ASP A OD2 1 ATOM 1886 N N . ARG A 1 239 ? -7.875 42.025 1.726 1.00 32.51 ? 292 ARG A N 1 ATOM 1887 C CA . ARG A 1 239 ? -9.095 41.269 1.409 1.00 28.96 ? 292 ARG A CA 1 ATOM 1888 C C . ARG A 1 239 ? -10.261 42.236 1.300 1.00 28.51 ? 292 ARG A C 1 ATOM 1889 O O . ARG A 1 239 ? -11.406 41.833 1.208 1.00 27.48 ? 292 ARG A O 1 ATOM 1890 C CB . ARG A 1 239 ? -9.423 40.215 2.481 1.00 28.47 ? 292 ARG A CB 1 ATOM 1891 C CG . ARG A 1 239 ? -8.719 38.895 2.312 1.00 29.02 ? 292 ARG A CG 1 ATOM 1892 C CD . ARG A 1 239 ? -8.926 37.940 3.484 1.00 27.95 ? 292 ARG A CD 1 ATOM 1893 N NE . ARG A 1 239 ? -10.322 37.529 3.667 1.00 28.61 ? 292 ARG A NE 1 ATOM 1894 C CZ . ARG A 1 239 ? -10.873 36.453 3.114 1.00 30.87 ? 292 ARG A CZ 1 ATOM 1895 N NH1 . ARG A 1 239 ? -10.158 35.674 2.313 1.00 32.41 ? 292 ARG A NH1 1 ATOM 1896 N NH2 . ARG A 1 239 ? -12.148 36.152 3.347 1.00 30.21 ? 292 ARG A NH2 1 ATOM 1897 N N . ASN A 1 240 ? -9.974 43.526 1.335 1.00 30.65 ? 293 ASN A N 1 ATOM 1898 C CA . ASN A 1 240 ? -11.025 44.499 1.588 1.00 27.54 ? 293 ASN A CA 1 ATOM 1899 C C . ASN A 1 240 ? -11.618 45.081 0.307 1.00 28.04 ? 293 ASN A C 1 ATOM 1900 O O . ASN A 1 240 ? -12.525 45.905 0.363 1.00 29.63 ? 293 ASN A O 1 ATOM 1901 C CB . ASN A 1 240 ? -10.519 45.613 2.503 1.00 28.29 ? 293 ASN A CB 1 ATOM 1902 C CG . ASN A 1 240 ? -9.334 46.362 1.920 1.00 30.32 ? 293 ASN A CG 1 ATOM 1903 O OD1 . ASN A 1 240 ? -8.625 45.859 1.047 1.00 31.65 ? 293 ASN A OD1 1 ATOM 1904 N ND2 . ASN A 1 240 ? -9.111 47.571 2.410 1.00 32.17 ? 293 ASN A ND2 1 ATOM 1905 N N . ASP A 1 241 ? -11.115 44.648 -0.845 1.00 28.83 ? 294 ASP A N 1 ATOM 1906 C CA . ASP A 1 241 ? -11.611 45.157 -2.113 1.00 29.40 ? 294 ASP A CA 1 ATOM 1907 C C . ASP A 1 241 ? -12.390 44.111 -2.872 1.00 29.35 ? 294 ASP A C 1 ATOM 1908 O O . ASP A 1 241 ? -11.821 43.171 -3.435 1.00 29.59 ? 294 ASP A O 1 ATOM 1909 C CB . ASP A 1 241 ? -10.473 45.660 -2.991 1.00 30.76 ? 294 ASP A CB 1 ATOM 1910 C CG . ASP A 1 241 ? -10.975 46.346 -4.241 1.00 31.80 ? 294 ASP A CG 1 ATOM 1911 O OD1 . ASP A 1 241 ? -12.098 46.017 -4.671 1.00 35.59 ? 294 ASP A OD1 1 ATOM 1912 O OD2 . ASP A 1 241 ? -10.331 47.227 -4.855 1.00 33.20 ? 294 ASP A OD2 1 ATOM 1913 N N . PRO A 1 242 ? -13.701 44.288 -2.904 1.00 27.84 ? 295 PRO A N 1 ATOM 1914 C CA . PRO A 1 242 ? -14.603 43.224 -3.346 1.00 26.49 ? 295 PRO A CA 1 ATOM 1915 C C . PRO A 1 242 ? -14.474 42.967 -4.846 1.00 27.74 ? 295 PRO A C 1 ATOM 1916 O O . PRO A 1 242 ? -14.728 41.854 -5.287 1.00 31.30 ? 295 PRO A O 1 ATOM 1917 C CB . PRO A 1 242 ? -16.004 43.738 -2.974 1.00 22.75 ? 295 PRO A CB 1 ATOM 1918 C CG . PRO A 1 242 ? -15.838 45.085 -2.431 1.00 25.39 ? 295 PRO A CG 1 ATOM 1919 C CD . PRO A 1 242 ? -14.405 45.521 -2.537 1.00 25.01 ? 295 PRO A CD 1 ATOM 1920 N N . MET A 1 243 ? -14.062 43.967 -5.614 1.00 32.50 ? 296 MET A N 1 ATOM 1921 C CA . MET A 1 243 ? -13.695 43.739 -7.019 1.00 35.12 ? 296 MET A CA 1 ATOM 1922 C C . MET A 1 243 ? -12.392 42.953 -7.163 1.00 34.15 ? 296 MET A C 1 ATOM 1923 O O . MET A 1 243 ? -12.291 42.066 -8.000 1.00 32.46 ? 296 MET A O 1 ATOM 1924 C CB . MET A 1 243 ? -13.573 45.063 -7.766 1.00 35.63 ? 296 MET A CB 1 ATOM 1925 C CG . MET A 1 243 ? -14.885 45.772 -7.944 1.00 37.62 ? 296 MET A CG 1 ATOM 1926 S SD . MET A 1 243 ? -15.918 45.102 -9.284 1.00 38.66 ? 296 MET A SD 1 ATOM 1927 C CE . MET A 1 243 ? -16.940 46.503 -9.504 1.00 37.63 ? 296 MET A CE 1 ATOM 1928 N N . LEU A 1 244 ? -11.399 43.264 -6.339 1.00 34.67 ? 297 LEU A N 1 ATOM 1929 C CA . LEU A 1 244 ? -10.200 42.438 -6.283 1.00 34.77 ? 297 LEU A CA 1 ATOM 1930 C C . LEU A 1 244 ? -10.559 41.018 -5.866 1.00 33.75 ? 297 LEU A C 1 ATOM 1931 O O . LEU A 1 244 ? -10.003 40.043 -6.383 1.00 33.35 ? 297 LEU A O 1 ATOM 1932 C CB . LEU A 1 244 ? -9.182 43.029 -5.306 1.00 37.38 ? 297 LEU A CB 1 ATOM 1933 C CG . LEU A 1 244 ? -8.343 44.195 -5.830 1.00 39.52 ? 297 LEU A CG 1 ATOM 1934 C CD1 . LEU A 1 244 ? -6.869 43.993 -5.480 1.00 40.36 ? 297 LEU A CD1 1 ATOM 1935 C CD2 . LEU A 1 244 ? -8.529 44.345 -7.329 1.00 39.50 ? 297 LEU A CD2 1 ATOM 1936 N N . LEU A 1 245 ? -11.488 40.910 -4.921 1.00 31.42 ? 298 LEU A N 1 ATOM 1937 C CA . LEU A 1 245 ? -11.756 39.645 -4.243 1.00 31.35 ? 298 LEU A CA 1 ATOM 1938 C C . LEU A 1 245 ? -12.528 38.678 -5.157 1.00 29.89 ? 298 LEU A C 1 ATOM 1939 O O . LEU A 1 245 ? -12.367 37.464 -5.060 1.00 28.89 ? 298 LEU A O 1 ATOM 1940 C CB . LEU A 1 245 ? -12.546 39.901 -2.954 1.00 31.69 ? 298 LEU A CB 1 ATOM 1941 C CG . LEU A 1 245 ? -11.940 39.472 -1.616 1.00 34.31 ? 298 LEU A CG 1 ATOM 1942 C CD1 . LEU A 1 245 ? -12.869 38.491 -0.899 1.00 34.86 ? 298 LEU A CD1 1 ATOM 1943 C CD2 . LEU A 1 245 ? -10.559 38.868 -1.800 1.00 34.87 ? 298 LEU A CD2 1 ATOM 1944 N N . TYR A 1 246 ? -13.351 39.223 -6.051 1.00 30.12 ? 299 TYR A N 1 ATOM 1945 C CA . TYR A 1 246 ? -14.222 38.409 -6.910 1.00 31.44 ? 299 TYR A CA 1 ATOM 1946 C C . TYR A 1 246 ? -13.539 37.957 -8.210 1.00 34.30 ? 299 TYR A C 1 ATOM 1947 O O . TYR A 1 246 ? -13.471 38.708 -9.186 1.00 33.71 ? 299 TYR A O 1 ATOM 1948 C CB . TYR A 1 246 ? -15.486 39.198 -7.249 1.00 30.71 ? 299 TYR A CB 1 ATOM 1949 C CG . TYR A 1 246 ? -16.566 38.418 -7.977 1.00 32.76 ? 299 TYR A CG 1 ATOM 1950 C CD1 . TYR A 1 246 ? -16.459 38.139 -9.336 1.00 31.74 ? 299 TYR A CD1 1 ATOM 1951 C CD2 . TYR A 1 246 ? -17.714 37.993 -7.313 1.00 33.85 ? 299 TYR A CD2 1 ATOM 1952 C CE1 . TYR A 1 246 ? -17.450 37.444 -10.005 1.00 30.98 ? 299 TYR A CE1 1 ATOM 1953 C CE2 . TYR A 1 246 ? -18.707 37.289 -7.976 1.00 32.76 ? 299 TYR A CE2 1 ATOM 1954 C CZ . TYR A 1 246 ? -18.571 37.022 -9.326 1.00 32.65 ? 299 TYR A CZ 1 ATOM 1955 O OH . TYR A 1 246 ? -19.563 36.335 -9.997 1.00 31.55 ? 299 TYR A OH 1 ATOM 1956 N N . ASN A 1 247 ? -13.062 36.717 -8.217 1.00 35.40 ? 300 ASN A N 1 ATOM 1957 C CA . ASN A 1 247 ? -12.492 36.102 -9.407 1.00 35.16 ? 300 ASN A CA 1 ATOM 1958 C C . ASN A 1 247 ? -13.201 34.803 -9.754 1.00 34.44 ? 300 ASN A C 1 ATOM 1959 O O . ASN A 1 247 ? -13.004 33.794 -9.081 1.00 33.91 ? 300 ASN A O 1 ATOM 1960 C CB . ASN A 1 247 ? -11.012 35.781 -9.183 1.00 37.20 ? 300 ASN A CB 1 ATOM 1961 C CG . ASN A 1 247 ? -10.276 36.890 -8.479 1.00 39.06 ? 300 ASN A CG 1 ATOM 1962 O OD1 . ASN A 1 247 ? -9.948 37.917 -9.084 1.00 42.46 ? 300 ASN A OD1 1 ATOM 1963 N ND2 . ASN A 1 247 ? -10.007 36.697 -7.192 1.00 36.15 ? 300 ASN A ND2 1 ATOM 1964 N N . LYS A 1 248 ? -14.006 34.817 -10.813 1.00 34.40 ? 301 LYS A N 1 ATOM 1965 C CA . LYS A 1 248 ? -14.860 33.673 -11.130 1.00 34.54 ? 301 LYS A CA 1 ATOM 1966 C C . LYS A 1 248 ? -14.217 32.676 -12.105 1.00 34.66 ? 301 LYS A C 1 ATOM 1967 O O . LYS A 1 248 ? -13.849 33.026 -13.226 1.00 33.96 ? 301 LYS A O 1 ATOM 1968 C CB . LYS A 1 248 ? -16.197 34.150 -11.695 1.00 33.95 ? 301 LYS A CB 1 ATOM 1969 C CG . LYS A 1 248 ? -17.084 33.028 -12.189 1.00 33.17 ? 301 LYS A CG 1 ATOM 1970 C CD . LYS A 1 248 ? -18.462 33.536 -12.546 1.00 32.03 ? 301 LYS A CD 1 ATOM 1971 C CE . LYS A 1 248 ? -19.497 33.039 -11.556 1.00 30.67 ? 301 LYS A CE 1 ATOM 1972 N NZ . LYS A 1 248 ? -20.660 33.957 -11.432 1.00 28.74 ? 301 LYS A NZ 1 ATOM 1973 N N . MET A 1 249 ? -14.114 31.429 -11.659 1.00 34.54 ? 302 MET A N 1 ATOM 1974 C CA . MET A 1 249 ? -13.475 30.365 -12.413 1.00 35.12 ? 302 MET A CA 1 ATOM 1975 C C . MET A 1 249 ? -14.460 29.235 -12.618 1.00 36.00 ? 302 MET A C 1 ATOM 1976 O O . MET A 1 249 ? -15.418 29.102 -11.855 1.00 39.24 ? 302 MET A O 1 ATOM 1977 C CB . MET A 1 249 ? -12.299 29.811 -11.621 1.00 36.43 ? 302 MET A CB 1 ATOM 1978 C CG . MET A 1 249 ? -10.981 30.404 -11.988 1.00 38.81 ? 302 MET A CG 1 ATOM 1979 S SD . MET A 1 249 ? -9.925 30.561 -10.569 1.00 38.96 ? 302 MET A SD 1 ATOM 1980 C CE . MET A 1 249 ? -9.906 32.329 -10.394 1.00 36.36 ? 302 MET A CE 1 ATOM 1981 N N . THR A 1 250 ? -14.201 28.396 -13.616 1.00 35.01 ? 303 THR A N 1 ATOM 1982 C CA . THR A 1 250 ? -14.691 27.022 -13.607 1.00 33.55 ? 303 THR A CA 1 ATOM 1983 C C . THR A 1 250 ? -13.790 26.155 -12.764 1.00 31.68 ? 303 THR A C 1 ATOM 1984 O O . THR A 1 250 ? -12.588 26.381 -12.704 1.00 31.88 ? 303 THR A O 1 ATOM 1985 C CB . THR A 1 250 ? -14.757 26.441 -15.047 1.00 34.50 ? 303 THR A CB 1 ATOM 1986 O OG1 . THR A 1 250 ? -13.494 25.858 -15.404 1.00 34.99 ? 303 THR A OG1 1 ATOM 1987 C CG2 . THR A 1 250 ? -14.953 27.535 -16.068 1.00 34.43 ? 303 THR A CG2 1 ATOM 1988 N N . LEU A 1 251 ? -14.371 25.136 -12.141 1.00 32.01 ? 304 LEU A N 1 ATOM 1989 C CA . LEU A 1 251 ? -13.591 24.042 -11.598 1.00 33.68 ? 304 LEU A CA 1 ATOM 1990 C C . LEU A 1 251 ? -12.420 23.716 -12.507 1.00 35.57 ? 304 LEU A C 1 ATOM 1991 O O . LEU A 1 251 ? -11.321 23.445 -12.034 1.00 36.09 ? 304 LEU A O 1 ATOM 1992 C CB . LEU A 1 251 ? -14.466 22.802 -11.406 1.00 35.17 ? 304 LEU A CB 1 ATOM 1993 C CG . LEU A 1 251 ? -15.229 22.816 -10.089 1.00 36.40 ? 304 LEU A CG 1 ATOM 1994 C CD1 . LEU A 1 251 ? -14.970 21.557 -9.295 1.00 38.26 ? 304 LEU A CD1 1 ATOM 1995 C CD2 . LEU A 1 251 ? -14.826 24.044 -9.293 1.00 36.51 ? 304 LEU A CD2 1 ATOM 1996 N N . ALA A 1 252 ? -12.655 23.732 -13.816 1.00 36.00 ? 305 ALA A N 1 ATOM 1997 C CA . ALA A 1 252 ? -11.601 23.406 -14.761 1.00 37.92 ? 305 ALA A CA 1 ATOM 1998 C C . ALA A 1 252 ? -10.404 24.311 -14.516 1.00 37.09 ? 305 ALA A C 1 ATOM 1999 O O . ALA A 1 252 ? -9.359 23.867 -14.063 1.00 35.95 ? 305 ALA A O 1 ATOM 2000 C CB . ALA A 1 252 ? -12.099 23.546 -16.205 1.00 38.45 ? 305 ALA A CB 1 ATOM 2001 N N . GLN A 1 253 ? -10.561 25.590 -14.805 1.00 40.08 ? 306 GLN A N 1 ATOM 2002 C CA . GLN A 1 253 ? -9.504 26.536 -14.523 1.00 42.25 ? 306 GLN A CA 1 ATOM 2003 C C . GLN A 1 253 ? -8.894 26.198 -13.162 1.00 43.10 ? 306 GLN A C 1 ATOM 2004 O O . GLN A 1 253 ? -7.679 26.159 -13.004 1.00 42.79 ? 306 GLN A O 1 ATOM 2005 C CB . GLN A 1 253 ? -10.057 27.957 -14.559 1.00 43.65 ? 306 GLN A CB 1 ATOM 2006 C CG . GLN A 1 253 ? -11.279 28.107 -15.455 1.00 45.59 ? 306 GLN A CG 1 ATOM 2007 C CD . GLN A 1 253 ? -11.382 29.482 -16.094 1.00 47.67 ? 306 GLN A CD 1 ATOM 2008 O OE1 . GLN A 1 253 ? -10.432 29.948 -16.722 1.00 50.41 ? 306 GLN A OE1 1 ATOM 2009 N NE2 . GLN A 1 253 ? -12.538 30.130 -15.942 1.00 46.16 ? 306 GLN A NE2 1 ATOM 2010 N N . ILE A 1 254 ? -9.743 25.927 -12.181 1.00 44.51 ? 307 ILE A N 1 ATOM 2011 C CA . ILE A 1 254 ? -9.272 25.791 -10.810 1.00 45.05 ? 307 ILE A CA 1 ATOM 2012 C C . ILE A 1 254 ? -8.307 24.623 -10.705 1.00 44.58 ? 307 ILE A C 1 ATOM 2013 O O . ILE A 1 254 ? -7.222 24.750 -10.141 1.00 46.57 ? 307 ILE A O 1 ATOM 2014 C CB . ILE A 1 254 ? -10.459 25.606 -9.846 1.00 45.20 ? 307 ILE A CB 1 ATOM 2015 C CG1 . ILE A 1 254 ? -11.150 26.949 -9.611 1.00 45.85 ? 307 ILE A CG1 1 ATOM 2016 C CG2 . ILE A 1 254 ? -9.988 25.017 -8.528 1.00 45.04 ? 307 ILE A CG2 1 ATOM 2017 C CD1 . ILE A 1 254 ? -12.416 26.845 -8.799 1.00 46.86 ? 307 ILE A CD1 1 ATOM 2018 N N . GLN A 1 255 ? -8.706 23.489 -11.264 1.00 44.34 ? 308 GLN A N 1 ATOM 2019 C CA . GLN A 1 255 ? -7.893 22.280 -11.217 1.00 45.04 ? 308 GLN A CA 1 ATOM 2020 C C . GLN A 1 255 ? -6.551 22.483 -11.909 1.00 45.47 ? 308 GLN A C 1 ATOM 2021 O O . GLN A 1 255 ? -5.564 21.852 -11.547 1.00 46.12 ? 308 GLN A O 1 ATOM 2022 C CB . GLN A 1 255 ? -8.630 21.113 -11.876 1.00 42.57 ? 308 GLN A CB 1 ATOM 2023 C CG . GLN A 1 255 ? -7.882 19.796 -11.781 1.00 41.19 ? 308 GLN A CG 1 ATOM 2024 C CD . GLN A 1 255 ? -7.794 19.273 -10.362 1.00 41.50 ? 308 GLN A CD 1 ATOM 2025 O OE1 . GLN A 1 255 ? -8.810 18.951 -9.748 1.00 37.96 ? 308 GLN A OE1 1 ATOM 2026 N NE2 . GLN A 1 255 ? -6.579 19.183 -9.839 1.00 43.69 ? 308 GLN A NE2 1 ATOM 2027 N N . ASN A 1 256 ? -6.524 23.363 -12.903 1.00 47.47 ? 309 ASN A N 1 ATOM 2028 C CA . ASN A 1 256 ? -5.339 23.550 -13.730 1.00 51.10 ? 309 ASN A CA 1 ATOM 2029 C C . ASN A 1 256 ? -4.541 24.786 -13.317 1.00 50.24 ? 309 ASN A C 1 ATOM 2030 O O . ASN A 1 256 ? -3.409 24.979 -13.760 1.00 51.72 ? 309 ASN A O 1 ATOM 2031 C CB . ASN A 1 256 ? -5.734 23.660 -15.211 1.00 53.83 ? 309 ASN A CB 1 ATOM 2032 C CG . ASN A 1 256 ? -5.820 22.300 -15.908 1.00 56.00 ? 309 ASN A CG 1 ATOM 2033 O OD1 . ASN A 1 256 ? -6.263 21.304 -15.319 1.00 58.43 ? 309 ASN A OD1 1 ATOM 2034 N ND2 . ASN A 1 256 ? -5.404 22.258 -17.172 1.00 55.80 ? 309 ASN A ND2 1 ATOM 2035 N N . ASN A 1 257 ? -5.134 25.624 -12.475 1.00 47.57 ? 310 ASN A N 1 ATOM 2036 C CA . ASN A 1 257 ? -4.462 26.828 -12.008 1.00 46.58 ? 310 ASN A CA 1 ATOM 2037 C C . ASN A 1 257 ? -4.140 26.799 -10.517 1.00 44.62 ? 310 ASN A C 1 ATOM 2038 O O . ASN A 1 257 ? -3.415 27.664 -10.026 1.00 44.96 ? 310 ASN A O 1 ATOM 2039 C CB . ASN A 1 257 ? -5.319 28.053 -12.311 1.00 48.08 ? 310 ASN A CB 1 ATOM 2040 C CG . ASN A 1 257 ? -5.049 28.618 -13.683 1.00 49.64 ? 310 ASN A CG 1 ATOM 2041 O OD1 . ASN A 1 257 ? -4.064 28.256 -14.327 1.00 51.50 ? 310 ASN A OD1 1 ATOM 2042 N ND2 . ASN A 1 257 ? -5.919 29.513 -14.142 1.00 49.78 ? 310 ASN A ND2 1 ATOM 2043 N N . PHE A 1 258 ? -4.684 25.817 -9.801 1.00 40.22 ? 311 PHE A N 1 ATOM 2044 C CA . PHE A 1 258 ? -4.520 25.746 -8.352 1.00 38.98 ? 311 PHE A CA 1 ATOM 2045 C C . PHE A 1 258 ? -4.441 24.314 -7.869 1.00 39.98 ? 311 PHE A C 1 ATOM 2046 O O . PHE A 1 258 ? -5.222 23.892 -7.012 1.00 38.96 ? 311 PHE A O 1 ATOM 2047 C CB . PHE A 1 258 ? -5.678 26.440 -7.641 1.00 36.58 ? 311 PHE A CB 1 ATOM 2048 C CG . PHE A 1 258 ? -5.708 27.908 -7.852 1.00 33.78 ? 311 PHE A CG 1 ATOM 2049 C CD1 . PHE A 1 258 ? -4.653 28.693 -7.443 1.00 32.26 ? 311 PHE A CD1 1 ATOM 2050 C CD2 . PHE A 1 258 ? -6.789 28.509 -8.468 1.00 34.09 ? 311 PHE A CD2 1 ATOM 2051 C CE1 . PHE A 1 258 ? -4.676 30.052 -7.637 1.00 31.47 ? 311 PHE A CE1 1 ATOM 2052 C CE2 . PHE A 1 258 ? -6.814 29.867 -8.669 1.00 32.44 ? 311 PHE A CE2 1 ATOM 2053 C CZ . PHE A 1 258 ? -5.754 30.638 -8.249 1.00 32.10 ? 311 PHE A CZ 1 ATOM 2054 N N . SER A 1 259 ? -3.484 23.578 -8.417 1.00 40.83 ? 312 SER A N 1 ATOM 2055 C CA . SER A 1 259 ? -3.287 22.180 -8.078 1.00 41.73 ? 312 SER A CA 1 ATOM 2056 C C . SER A 1 259 ? -2.850 22.038 -6.627 1.00 41.48 ? 312 SER A C 1 ATOM 2057 O O . SER A 1 259 ? -2.173 22.911 -6.085 1.00 40.24 ? 312 SER A O 1 ATOM 2058 C CB . SER A 1 259 ? -2.219 21.586 -8.991 1.00 40.81 ? 312 SER A CB 1 ATOM 2059 O OG . SER A 1 259 ? -1.236 22.563 -9.272 1.00 41.04 ? 312 SER A OG 1 ATOM 2060 N N . LEU A 1 260 ? -3.235 20.929 -6.008 1.00 42.42 ? 313 LEU A N 1 ATOM 2061 C CA . LEU A 1 260 ? -2.702 20.544 -4.712 1.00 44.61 ? 313 LEU A CA 1 ATOM 2062 C C . LEU A 1 260 ? -2.293 19.079 -4.742 1.00 46.10 ? 313 LEU A C 1 ATOM 2063 O O . LEU A 1 260 ? -2.967 18.253 -5.358 1.00 47.61 ? 313 LEU A O 1 ATOM 2064 C CB . LEU A 1 260 ? -3.754 20.760 -3.624 1.00 45.04 ? 313 LEU A CB 1 ATOM 2065 C CG . LEU A 1 260 ? -4.222 22.198 -3.399 1.00 44.85 ? 313 LEU A CG 1 ATOM 2066 C CD1 . LEU A 1 260 ? -5.465 22.202 -2.533 1.00 45.87 ? 313 LEU A CD1 1 ATOM 2067 C CD2 . LEU A 1 260 ? -3.136 23.032 -2.758 1.00 44.94 ? 313 LEU A CD2 1 ATOM 2068 N N . GLU A 1 261 ? -1.191 18.759 -4.075 1.00 48.91 ? 314 GLU A N 1 ATOM 2069 C CA . GLU A 1 261 ? -0.806 17.367 -3.860 1.00 50.70 ? 314 GLU A CA 1 ATOM 2070 C C . GLU A 1 261 ? -0.891 17.031 -2.379 1.00 50.58 ? 314 GLU A C 1 ATOM 2071 O O . GLU A 1 261 ? -0.006 17.355 -1.591 1.00 50.53 ? 314 GLU A O 1 ATOM 2072 C CB . GLU A 1 261 ? 0.605 17.100 -4.391 1.00 52.96 ? 314 GLU A CB 1 ATOM 2073 C CG . GLU A 1 261 ? 1.183 15.754 -3.974 1.00 55.94 ? 314 GLU A CG 1 ATOM 2074 C CD . GLU A 1 261 ? 2.025 15.094 -5.061 1.00 57.45 ? 314 GLU A CD 1 ATOM 2075 O OE1 . GLU A 1 261 ? 1.522 14.151 -5.718 1.00 58.79 ? 314 GLU A OE1 1 ATOM 2076 O OE2 . GLU A 1 261 ? 3.191 15.508 -5.253 1.00 57.00 ? 314 GLU A OE2 1 ATOM 2077 N N . ILE A 1 262 ? -1.985 16.393 -2.000 1.00 52.11 ? 315 ILE A N 1 ATOM 2078 C CA . ILE A 1 262 ? -2.185 16.002 -0.620 1.00 52.33 ? 315 ILE A CA 1 ATOM 2079 C C . ILE A 1 262 ? -1.892 14.520 -0.486 1.00 52.97 ? 315 ILE A C 1 ATOM 2080 O O . ILE A 1 262 ? -2.526 13.691 -1.135 1.00 51.68 ? 315 ILE A O 1 ATOM 2081 C CB . ILE A 1 262 ? -3.630 16.309 -0.181 1.00 51.10 ? 315 ILE A CB 1 ATOM 2082 C CG1 . ILE A 1 262 ? -3.965 17.787 -0.418 1.00 51.24 ? 315 ILE A CG1 1 ATOM 2083 C CG2 . ILE A 1 262 ? -3.827 15.945 1.283 1.00 50.33 ? 315 ILE A CG2 1 ATOM 2084 C CD1 . ILE A 1 262 ? -2.993 18.508 -1.342 1.00 51.95 ? 315 ILE A CD1 1 ATOM 2085 N N . ASN A 1 263 ? -0.919 14.193 0.354 1.00 56.10 ? 316 ASN A N 1 ATOM 2086 C CA . ASN A 1 263 ? -0.585 12.806 0.611 1.00 58.79 ? 316 ASN A CA 1 ATOM 2087 C C . ASN A 1 263 ? 0.108 12.207 -0.610 1.00 60.28 ? 316 ASN A C 1 ATOM 2088 O O . ASN A 1 263 ? 1.222 11.701 -0.526 1.00 61.75 ? 316 ASN A O 1 ATOM 2089 C CB . ASN A 1 263 ? -1.861 12.030 0.953 1.00 59.72 ? 316 ASN A CB 1 ATOM 2090 C CG . ASN A 1 263 ? -1.600 10.568 1.265 1.00 60.75 ? 316 ASN A CG 1 ATOM 2091 O OD1 . ASN A 1 263 ? -2.050 9.682 0.539 1.00 63.67 ? 316 ASN A OD1 1 ATOM 2092 N ND2 . ASN A 1 263 ? -0.892 10.307 2.357 1.00 60.13 ? 316 ASN A ND2 1 ATOM 2093 N N . GLY A 1 264 ? -0.554 12.288 -1.754 1.00 61.87 ? 317 GLY A N 1 ATOM 2094 C CA . GLY A 1 264 ? -0.028 11.718 -2.978 1.00 62.04 ? 317 GLY A CA 1 ATOM 2095 C C . GLY A 1 264 ? -1.161 11.424 -3.934 1.00 61.91 ? 317 GLY A C 1 ATOM 2096 O O . GLY A 1 264 ? -1.872 10.424 -3.784 1.00 63.06 ? 317 GLY A O 1 ATOM 2097 N N . LYS A 1 265 ? -1.347 12.305 -4.909 1.00 60.10 ? 318 LYS A N 1 ATOM 2098 C CA . LYS A 1 265 ? -2.601 12.350 -5.645 1.00 59.22 ? 318 LYS A CA 1 ATOM 2099 C C . LYS A 1 265 ? -2.392 12.861 -7.065 1.00 57.43 ? 318 LYS A C 1 ATOM 2100 O O . LYS A 1 265 ? -2.040 12.091 -7.956 1.00 58.34 ? 318 LYS A O 1 ATOM 2101 C CB . LYS A 1 265 ? -3.625 13.210 -4.906 1.00 59.72 ? 318 LYS A CB 1 ATOM 2102 C CG . LYS A 1 265 ? -4.735 12.392 -4.240 1.00 60.25 ? 318 LYS A CG 1 ATOM 2103 C CD . LYS A 1 265 ? -5.984 12.307 -5.116 1.00 60.09 ? 318 LYS A CD 1 ATOM 2104 C CE . LYS A 1 265 ? -7.128 11.592 -4.399 1.00 59.94 ? 318 LYS A CE 1 ATOM 2105 N NZ . LYS A 1 265 ? -8.239 11.217 -5.322 1.00 58.80 ? 318 LYS A NZ 1 ATOM 2106 N N . PRO A 1 266 ? -2.596 14.159 -7.271 1.00 53.87 ? 319 PRO A N 1 ATOM 2107 C CA . PRO A 1 266 ? -3.078 15.061 -6.230 1.00 51.96 ? 319 PRO A CA 1 ATOM 2108 C C . PRO A 1 266 ? -4.579 15.323 -6.336 1.00 47.89 ? 319 PRO A C 1 ATOM 2109 O O . PRO A 1 266 ? -5.348 14.419 -6.663 1.00 45.41 ? 319 PRO A O 1 ATOM 2110 C CB . PRO A 1 266 ? -2.315 16.350 -6.542 1.00 53.48 ? 319 PRO A CB 1 ATOM 2111 C CG . PRO A 1 266 ? -2.129 16.321 -8.062 1.00 53.74 ? 319 PRO A CG 1 ATOM 2112 C CD . PRO A 1 266 ? -2.343 14.884 -8.526 1.00 54.14 ? 319 PRO A CD 1 ATOM 2113 N N . PHE A 1 267 ? -4.979 16.564 -6.070 1.00 42.76 ? 320 PHE A N 1 ATOM 2114 C CA . PHE A 1 267 ? -6.260 16.841 -5.434 1.00 39.21 ? 320 PHE A CA 1 ATOM 2115 C C . PHE A 1 267 ? -7.321 16.981 -6.515 1.00 37.01 ? 320 PHE A C 1 ATOM 2116 O O . PHE A 1 267 ? -7.136 17.722 -7.484 1.00 33.65 ? 320 PHE A O 1 ATOM 2117 C CB . PHE A 1 267 ? -6.163 18.130 -4.602 1.00 37.95 ? 320 PHE A CB 1 ATOM 2118 C CG . PHE A 1 267 ? -7.354 18.385 -3.710 1.00 36.52 ? 320 PHE A CG 1 ATOM 2119 C CD1 . PHE A 1 267 ? -8.300 19.340 -4.051 1.00 37.65 ? 320 PHE A CD1 1 ATOM 2120 C CD2 . PHE A 1 267 ? -7.512 17.698 -2.520 1.00 37.08 ? 320 PHE A CD2 1 ATOM 2121 C CE1 . PHE A 1 267 ? -9.386 19.598 -3.223 1.00 36.68 ? 320 PHE A CE1 1 ATOM 2122 C CE2 . PHE A 1 267 ? -8.598 17.946 -1.695 1.00 37.27 ? 320 PHE A CE2 1 ATOM 2123 C CZ . PHE A 1 267 ? -9.533 18.897 -2.046 1.00 36.36 ? 320 PHE A CZ 1 ATOM 2124 N N . SER A 1 268 ? -8.435 16.277 -6.357 1.00 35.26 ? 321 SER A N 1 ATOM 2125 C CA . SER A 1 268 ? -9.515 16.387 -7.339 1.00 33.75 ? 321 SER A CA 1 ATOM 2126 C C . SER A 1 268 ? -10.567 17.377 -6.870 1.00 32.14 ? 321 SER A C 1 ATOM 2127 O O . SER A 1 268 ? -11.435 17.049 -6.060 1.00 30.29 ? 321 SER A O 1 ATOM 2128 C CB . SER A 1 268 ? -10.159 15.026 -7.616 1.00 31.85 ? 321 SER A CB 1 ATOM 2129 O OG . SER A 1 268 ? -11.106 15.136 -8.660 1.00 30.81 ? 321 SER A OG 1 ATOM 2130 N N . TRP A 1 269 ? -10.485 18.592 -7.389 1.00 32.44 ? 322 TRP A N 1 ATOM 2131 C CA . TRP A 1 269 ? -11.458 19.616 -7.058 1.00 35.38 ? 322 TRP A CA 1 ATOM 2132 C C . TRP A 1 269 ? -12.878 19.130 -7.402 1.00 37.48 ? 322 TRP A C 1 ATOM 2133 O O . TRP A 1 269 ? -13.809 19.281 -6.604 1.00 35.14 ? 322 TRP A O 1 ATOM 2134 C CB . TRP A 1 269 ? -11.117 20.910 -7.792 1.00 34.64 ? 322 TRP A CB 1 ATOM 2135 C CG . TRP A 1 269 ? -9.994 21.674 -7.150 1.00 35.94 ? 322 TRP A CG 1 ATOM 2136 C CD1 . TRP A 1 269 ? -8.679 21.640 -7.498 1.00 35.45 ? 322 TRP A CD1 1 ATOM 2137 C CD2 . TRP A 1 269 ? -10.088 22.584 -6.043 1.00 35.93 ? 322 TRP A CD2 1 ATOM 2138 N NE1 . TRP A 1 269 ? -7.950 22.472 -6.684 1.00 34.59 ? 322 TRP A NE1 1 ATOM 2139 C CE2 . TRP A 1 269 ? -8.791 23.063 -5.781 1.00 34.34 ? 322 TRP A CE2 1 ATOM 2140 C CE3 . TRP A 1 269 ? -11.141 23.050 -5.253 1.00 34.80 ? 322 TRP A CE3 1 ATOM 2141 C CZ2 . TRP A 1 269 ? -8.517 23.974 -4.763 1.00 35.71 ? 322 TRP A CZ2 1 ATOM 2142 C CZ3 . TRP A 1 269 ? -10.867 23.958 -4.242 1.00 35.74 ? 322 TRP A CZ3 1 ATOM 2143 C CH2 . TRP A 1 269 ? -9.568 24.410 -4.007 1.00 35.64 ? 322 TRP A CH2 1 ATOM 2144 N N . LEU A 1 270 ? -13.020 18.526 -8.579 1.00 36.76 ? 323 LEU A N 1 ATOM 2145 C CA . LEU A 1 270 ? -14.272 17.909 -9.000 1.00 38.70 ? 323 LEU A CA 1 ATOM 2146 C C . LEU A 1 270 ? -14.773 16.902 -7.980 1.00 38.75 ? 323 LEU A C 1 ATOM 2147 O O . LEU A 1 270 ? -15.962 16.833 -7.684 1.00 39.40 ? 323 LEU A O 1 ATOM 2148 C CB . LEU A 1 270 ? -14.068 17.191 -10.333 1.00 42.13 ? 323 LEU A CB 1 ATOM 2149 C CG . LEU A 1 270 ? -15.273 17.129 -11.268 1.00 44.70 ? 323 LEU A CG 1 ATOM 2150 C CD1 . LEU A 1 270 ? -16.156 18.366 -11.095 1.00 46.01 ? 323 LEU A CD1 1 ATOM 2151 C CD2 . LEU A 1 270 ? -14.795 16.995 -12.715 1.00 44.31 ? 323 LEU A CD2 1 ATOM 2152 N N . ASN A 1 271 ? -13.855 16.102 -7.461 1.00 37.62 ? 324 ASN A N 1 ATOM 2153 C CA . ASN A 1 271 ? -14.204 15.078 -6.503 1.00 37.05 ? 324 ASN A CA 1 ATOM 2154 C C . ASN A 1 271 ? -14.603 15.699 -5.171 1.00 36.89 ? 324 ASN A C 1 ATOM 2155 O O . ASN A 1 271 ? -15.654 15.379 -4.608 1.00 36.86 ? 324 ASN A O 1 ATOM 2156 C CB . ASN A 1 271 ? -13.018 14.143 -6.295 1.00 37.68 ? 324 ASN A CB 1 ATOM 2157 C CG . ASN A 1 271 ? -13.367 12.948 -5.438 1.00 38.16 ? 324 ASN A CG 1 ATOM 2158 O OD1 . ASN A 1 271 ? -12.711 12.677 -4.439 1.00 36.80 ? 324 ASN A OD1 1 ATOM 2159 N ND2 . ASN A 1 271 ? -14.416 12.234 -5.822 1.00 40.39 ? 324 ASN A ND2 1 ATOM 2160 N N . PHE A 1 272 ? -13.731 16.568 -4.671 1.00 35.92 ? 325 PHE A N 1 ATOM 2161 C CA . PHE A 1 272 ? -14.009 17.404 -3.510 1.00 33.08 ? 325 PHE A CA 1 ATOM 2162 C C . PHE A 1 272 ? -15.373 18.070 -3.622 1.00 31.85 ? 325 PHE A C 1 ATOM 2163 O O . PHE A 1 272 ? -16.198 17.953 -2.723 1.00 31.92 ? 325 PHE A O 1 ATOM 2164 C CB . PHE A 1 272 ? -12.903 18.451 -3.366 1.00 30.66 ? 325 PHE A CB 1 ATOM 2165 C CG . PHE A 1 272 ? -13.167 19.480 -2.311 1.00 30.19 ? 325 PHE A CG 1 ATOM 2166 C CD1 . PHE A 1 272 ? -13.014 20.824 -2.593 1.00 29.61 ? 325 PHE A CD1 1 ATOM 2167 C CD2 . PHE A 1 272 ? -13.547 19.107 -1.033 1.00 28.28 ? 325 PHE A CD2 1 ATOM 2168 C CE1 . PHE A 1 272 ? -13.238 21.775 -1.620 1.00 29.40 ? 325 PHE A CE1 1 ATOM 2169 C CE2 . PHE A 1 272 ? -13.770 20.053 -0.061 1.00 26.99 ? 325 PHE A CE2 1 ATOM 2170 C CZ . PHE A 1 272 ? -13.618 21.386 -0.352 1.00 27.53 ? 325 PHE A CZ 1 ATOM 2171 N N . THR A 1 273 ? -15.629 18.741 -4.736 1.00 32.19 ? 326 THR A N 1 ATOM 2172 C CA . THR A 1 273 ? -16.828 19.565 -4.841 1.00 32.27 ? 326 THR A CA 1 ATOM 2173 C C . THR A 1 273 ? -18.103 18.724 -4.909 1.00 35.58 ? 326 THR A C 1 ATOM 2174 O O . THR A 1 273 ? -19.180 19.193 -4.529 1.00 35.12 ? 326 THR A O 1 ATOM 2175 C CB . THR A 1 273 ? -16.737 20.468 -6.058 1.00 31.39 ? 326 THR A CB 1 ATOM 2176 O OG1 . THR A 1 273 ? -15.675 21.412 -5.881 1.00 31.79 ? 326 THR A OG1 1 ATOM 2177 C CG2 . THR A 1 273 ? -17.972 21.334 -6.177 1.00 31.70 ? 326 THR A CG2 1 ATOM 2178 N N . ASN A 1 274 ? -17.977 17.486 -5.385 1.00 36.78 ? 327 ASN A N 1 ATOM 2179 C CA . ASN A 1 274 ? -19.113 16.569 -5.475 1.00 38.57 ? 327 ASN A CA 1 ATOM 2180 C C . ASN A 1 274 ? -19.380 15.799 -4.184 1.00 38.47 ? 327 ASN A C 1 ATOM 2181 O O . ASN A 1 274 ? -20.524 15.443 -3.893 1.00 38.56 ? 327 ASN A O 1 ATOM 2182 C CB . ASN A 1 274 ? -18.907 15.559 -6.616 1.00 39.18 ? 327 ASN A CB 1 ATOM 2183 C CG . ASN A 1 274 ? -19.248 16.132 -7.982 1.00 39.72 ? 327 ASN A CG 1 ATOM 2184 O OD1 . ASN A 1 274 ? -20.306 16.735 -8.183 1.00 41.07 ? 327 ASN A OD1 1 ATOM 2185 N ND2 . ASN A 1 274 ? -18.351 15.934 -8.933 1.00 38.82 ? 327 ASN A ND2 1 ATOM 2186 N N . GLU A 1 275 ? -18.331 15.524 -3.414 1.00 38.70 ? 328 GLU A N 1 ATOM 2187 C CA . GLU A 1 275 ? -18.511 14.909 -2.102 1.00 36.58 ? 328 GLU A CA 1 ATOM 2188 C C . GLU A 1 275 ? -19.327 15.815 -1.198 1.00 35.12 ? 328 GLU A C 1 ATOM 2189 O O . GLU A 1 275 ? -20.068 15.336 -0.339 1.00 40.29 ? 328 GLU A O 1 ATOM 2190 C CB . GLU A 1 275 ? -17.166 14.618 -1.452 1.00 37.47 ? 328 GLU A CB 1 ATOM 2191 C CG . GLU A 1 275 ? -16.458 13.406 -2.017 1.00 37.53 ? 328 GLU A CG 1 ATOM 2192 C CD . GLU A 1 275 ? -17.046 12.109 -1.516 1.00 38.84 ? 328 GLU A CD 1 ATOM 2193 O OE1 . GLU A 1 275 ? -17.621 12.096 -0.406 1.00 41.74 ? 328 GLU A OE1 1 ATOM 2194 O OE2 . GLU A 1 275 ? -16.929 11.097 -2.231 1.00 42.36 ? 328 GLU A OE2 1 ATOM 2195 N N . ILE A 1 276 ? -19.198 17.122 -1.405 1.00 33.30 ? 329 ILE A N 1 ATOM 2196 C CA . ILE A 1 276 ? -19.978 18.095 -0.656 1.00 32.36 ? 329 ILE A CA 1 ATOM 2197 C C . ILE A 1 276 ? -21.390 18.145 -1.225 1.00 33.95 ? 329 ILE A C 1 ATOM 2198 O O . ILE A 1 276 ? -22.355 17.812 -0.544 1.00 37.01 ? 329 ILE A O 1 ATOM 2199 C CB . ILE A 1 276 ? -19.314 19.489 -0.717 1.00 30.62 ? 329 ILE A CB 1 ATOM 2200 C CG1 . ILE A 1 276 ? -18.066 19.540 0.172 1.00 31.89 ? 329 ILE A CG1 1 ATOM 2201 C CG2 . ILE A 1 276 ? -20.292 20.576 -0.285 1.00 29.38 ? 329 ILE A CG2 1 ATOM 2202 C CD1 . ILE A 1 276 ? -17.479 20.942 0.342 1.00 31.01 ? 329 ILE A CD1 1 ATOM 2203 N N . MET A 1 277 ? -21.497 18.548 -2.487 1.00 37.10 ? 330 MET A N 1 ATOM 2204 C CA . MET A 1 277 ? -22.785 18.762 -3.128 1.00 36.44 ? 330 MET A CA 1 ATOM 2205 C C . MET A 1 277 ? -23.588 17.467 -3.180 1.00 37.11 ? 330 MET A C 1 ATOM 2206 O O . MET A 1 277 ? -24.813 17.491 -3.166 1.00 37.35 ? 330 MET A O 1 ATOM 2207 C CB . MET A 1 277 ? -22.591 19.293 -4.545 1.00 34.42 ? 330 MET A CB 1 ATOM 2208 C CG . MET A 1 277 ? -22.194 20.753 -4.626 1.00 35.18 ? 330 MET A CG 1 ATOM 2209 S SD . MET A 1 277 ? -22.782 21.750 -3.245 1.00 35.77 ? 330 MET A SD 1 ATOM 2210 C CE . MET A 1 277 ? -24.537 21.687 -3.489 1.00 35.28 ? 330 MET A CE 1 ATOM 2211 N N . SER A 1 278 ? -22.892 16.339 -3.250 1.00 38.55 ? 331 SER A N 1 ATOM 2212 C CA . SER A 1 278 ? -23.547 15.041 -3.274 1.00 39.62 ? 331 SER A CA 1 ATOM 2213 C C . SER A 1 278 ? -24.505 14.938 -2.106 1.00 41.82 ? 331 SER A C 1 ATOM 2214 O O . SER A 1 278 ? -25.522 14.240 -2.167 1.00 43.13 ? 331 SER A O 1 ATOM 2215 C CB . SER A 1 278 ? -22.511 13.922 -3.197 1.00 39.73 ? 331 SER A CB 1 ATOM 2216 O OG . SER A 1 278 ? -21.836 13.930 -1.951 1.00 36.78 ? 331 SER A OG 1 ATOM 2217 N N . THR A 1 279 ? -24.166 15.637 -1.033 1.00 42.96 ? 332 THR A N 1 ATOM 2218 C CA . THR A 1 279 ? -24.790 15.399 0.252 1.00 44.35 ? 332 THR A CA 1 ATOM 2219 C C . THR A 1 279 ? -26.228 15.850 0.157 1.00 44.52 ? 332 THR A C 1 ATOM 2220 O O . THR A 1 279 ? -27.058 15.528 1.007 1.00 45.91 ? 332 THR A O 1 ATOM 2221 C CB . THR A 1 279 ? -24.063 16.187 1.345 1.00 43.42 ? 332 THR A CB 1 ATOM 2222 O OG1 . THR A 1 279 ? -23.619 15.292 2.367 1.00 44.87 ? 332 THR A OG1 1 ATOM 2223 C CG2 . THR A 1 279 ? -25.016 17.134 2.067 1.00 43.88 ? 332 THR A CG2 1 ATOM 2224 N N . VAL A 1 280 ? -26.510 16.610 -0.892 1.00 44.48 ? 333 VAL A N 1 ATOM 2225 C CA . VAL A 1 280 ? -27.867 17.039 -1.172 1.00 47.75 ? 333 VAL A CA 1 ATOM 2226 C C . VAL A 1 280 ? -28.272 16.733 -2.617 1.00 46.83 ? 333 VAL A C 1 ATOM 2227 O O . VAL A 1 280 ? -28.973 17.516 -3.247 1.00 44.65 ? 333 VAL A O 1 ATOM 2228 C CB . VAL A 1 280 ? -28.021 18.542 -0.902 1.00 48.09 ? 333 VAL A CB 1 ATOM 2229 C CG1 . VAL A 1 280 ? -29.341 19.046 -1.448 1.00 50.10 ? 333 VAL A CG1 1 ATOM 2230 C CG2 . VAL A 1 280 ? -27.914 18.821 0.588 1.00 48.68 ? 333 VAL A CG2 1 ATOM 2231 N N . ASN A 1 281 ? -27.834 15.590 -3.134 1.00 48.92 ? 334 ASN A N 1 ATOM 2232 C CA . ASN A 1 281 ? -28.296 15.125 -4.441 1.00 50.69 ? 334 ASN A CA 1 ATOM 2233 C C . ASN A 1 281 ? -28.184 16.218 -5.498 1.00 50.58 ? 334 ASN A C 1 ATOM 2234 O O . ASN A 1 281 ? -29.110 16.429 -6.277 1.00 50.04 ? 334 ASN A O 1 ATOM 2235 C CB . ASN A 1 281 ? -29.751 14.655 -4.351 1.00 51.27 ? 334 ASN A CB 1 ATOM 2236 C CG . ASN A 1 281 ? -30.202 13.895 -5.592 1.00 53.09 ? 334 ASN A CG 1 ATOM 2237 O OD1 . ASN A 1 281 ? -30.862 14.454 -6.474 1.00 53.79 ? 334 ASN A OD1 1 ATOM 2238 N ND2 . ASN A 1 281 ? -29.854 12.611 -5.660 1.00 53.74 ? 334 ASN A ND2 1 ATOM 2239 N N . ILE A 1 282 ? -27.047 16.906 -5.532 1.00 51.36 ? 335 ILE A N 1 ATOM 2240 C CA . ILE A 1 282 ? -26.755 17.826 -6.626 1.00 51.66 ? 335 ILE A CA 1 ATOM 2241 C C . ILE A 1 282 ? -25.443 17.493 -7.317 1.00 54.12 ? 335 ILE A C 1 ATOM 2242 O O . ILE A 1 282 ? -24.502 16.987 -6.697 1.00 53.21 ? 335 ILE A O 1 ATOM 2243 C CB . ILE A 1 282 ? -26.692 19.270 -6.134 1.00 50.85 ? 335 ILE A CB 1 ATOM 2244 C CG1 . ILE A 1 282 ? -28.048 19.707 -5.579 1.00 51.33 ? 335 ILE A CG1 1 ATOM 2245 C CG2 . ILE A 1 282 ? -26.282 20.171 -7.271 1.00 50.64 ? 335 ILE A CG2 1 ATOM 2246 C CD1 . ILE A 1 282 ? -28.199 21.206 -5.437 1.00 50.54 ? 335 ILE A CD1 1 ATOM 2247 N N . SER A 1 283 ? -25.394 17.808 -8.609 1.00 55.05 ? 336 SER A N 1 ATOM 2248 C CA . SER A 1 283 ? -24.375 17.291 -9.504 1.00 54.32 ? 336 SER A CA 1 ATOM 2249 C C . SER A 1 283 ? -23.567 18.444 -10.067 1.00 53.45 ? 336 SER A C 1 ATOM 2250 O O . SER A 1 283 ? -24.128 19.447 -10.506 1.00 52.21 ? 336 SER A O 1 ATOM 2251 C CB . SER A 1 283 ? -25.031 16.538 -10.655 1.00 56.04 ? 336 SER A CB 1 ATOM 2252 O OG . SER A 1 283 ? -25.854 17.411 -11.410 1.00 56.83 ? 336 SER A OG 1 ATOM 2253 N N . ILE A 1 284 ? -22.247 18.298 -10.061 1.00 52.94 ? 337 ILE A N 1 ATOM 2254 C CA . ILE A 1 284 ? -21.364 19.413 -10.368 1.00 51.23 ? 337 ILE A CA 1 ATOM 2255 C C . ILE A 1 284 ? -20.421 19.080 -11.510 1.00 49.56 ? 337 ILE A C 1 ATOM 2256 O O . ILE A 1 284 ? -19.645 18.129 -11.442 1.00 49.51 ? 337 ILE A O 1 ATOM 2257 C CB . ILE A 1 284 ? -20.557 19.813 -9.132 1.00 51.49 ? 337 ILE A CB 1 ATOM 2258 C CG1 . ILE A 1 284 ? -21.485 20.427 -8.083 1.00 51.95 ? 337 ILE A CG1 1 ATOM 2259 C CG2 . ILE A 1 284 ? -19.464 20.793 -9.520 1.00 50.46 ? 337 ILE A CG2 1 ATOM 2260 C CD1 . ILE A 1 284 ? -22.510 21.372 -8.667 1.00 52.30 ? 337 ILE A CD1 1 ATOM 2261 N N . THR A 1 285 ? -20.497 19.885 -12.560 1.00 50.42 ? 338 THR A N 1 ATOM 2262 C CA . THR A 1 285 ? -19.603 19.764 -13.700 1.00 49.39 ? 338 THR A CA 1 ATOM 2263 C C . THR A 1 285 ? -18.287 20.481 -13.434 1.00 48.84 ? 338 THR A C 1 ATOM 2264 O O . THR A 1 285 ? -18.273 21.605 -12.937 1.00 43.21 ? 338 THR A O 1 ATOM 2265 C CB . THR A 1 285 ? -20.280 20.375 -14.937 1.00 49.61 ? 338 THR A CB 1 ATOM 2266 O OG1 . THR A 1 285 ? -21.236 19.451 -15.479 1.00 49.68 ? 338 THR A OG1 1 ATOM 2267 C CG2 . THR A 1 285 ? -19.277 20.593 -16.053 1.00 50.75 ? 338 THR A CG2 1 ATOM 2268 N N . ASN A 1 286 ? -17.182 19.829 -13.783 1.00 50.94 ? 339 ASN A N 1 ATOM 2269 C CA . ASN A 1 286 ? -15.912 20.524 -13.993 1.00 51.01 ? 339 ASN A CA 1 ATOM 2270 C C . ASN A 1 286 ? -16.060 21.805 -14.807 1.00 48.52 ? 339 ASN A C 1 ATOM 2271 O O . ASN A 1 286 ? -15.105 22.558 -14.972 1.00 49.54 ? 339 ASN A O 1 ATOM 2272 C CB . ASN A 1 286 ? -14.904 19.600 -14.673 1.00 52.04 ? 339 ASN A CB 1 ATOM 2273 C CG . ASN A 1 286 ? -13.658 19.396 -13.845 1.00 54.24 ? 339 ASN A CG 1 ATOM 2274 O OD1 . ASN A 1 286 ? -13.000 18.356 -13.932 1.00 56.38 ? 339 ASN A OD1 1 ATOM 2275 N ND2 . ASN A 1 286 ? -13.326 20.387 -13.025 1.00 55.26 ? 339 ASN A ND2 1 ATOM 2276 N N . GLU A 1 287 ? -17.260 22.060 -15.305 1.00 46.61 ? 340 GLU A N 1 ATOM 2277 C CA . GLU A 1 287 ? -17.515 23.285 -16.048 1.00 45.90 ? 340 GLU A CA 1 ATOM 2278 C C . GLU A 1 287 ? -18.341 24.259 -15.206 1.00 45.04 ? 340 GLU A C 1 ATOM 2279 O O . GLU A 1 287 ? -18.703 25.350 -15.657 1.00 43.86 ? 340 GLU A O 1 ATOM 2280 C CB . GLU A 1 287 ? -18.227 22.948 -17.359 1.00 47.81 ? 340 GLU A CB 1 ATOM 2281 C CG . GLU A 1 287 ? -17.521 21.873 -18.172 1.00 48.43 ? 340 GLU A CG 1 ATOM 2282 C CD . GLU A 1 287 ? -18.377 20.643 -18.384 1.00 51.23 ? 340 GLU A CD 1 ATOM 2283 O OE1 . GLU A 1 287 ? -19.545 20.803 -18.802 1.00 52.70 ? 340 GLU A OE1 1 ATOM 2284 O OE2 . GLU A 1 287 ? -17.881 19.518 -18.133 1.00 52.78 ? 340 GLU A OE2 1 ATOM 2285 N N . GLU A 1 288 ? -18.619 23.850 -13.969 1.00 43.29 ? 341 GLU A N 1 ATOM 2286 C CA . GLU A 1 288 ? -19.307 24.685 -12.991 1.00 40.88 ? 341 GLU A CA 1 ATOM 2287 C C . GLU A 1 288 ? -18.536 25.961 -12.674 1.00 39.12 ? 341 GLU A C 1 ATOM 2288 O O . GLU A 1 288 ? -17.314 25.944 -12.544 1.00 35.95 ? 341 GLU A O 1 ATOM 2289 C CB . GLU A 1 288 ? -19.510 23.896 -11.701 1.00 41.08 ? 341 GLU A CB 1 ATOM 2290 C CG . GLU A 1 288 ? -20.223 24.679 -10.615 1.00 42.56 ? 341 GLU A CG 1 ATOM 2291 C CD . GLU A 1 288 ? -21.731 24.576 -10.718 1.00 42.60 ? 341 GLU A CD 1 ATOM 2292 O OE1 . GLU A 1 288 ? -22.429 25.132 -9.841 1.00 41.34 ? 341 GLU A OE1 1 ATOM 2293 O OE2 . GLU A 1 288 ? -22.216 23.941 -11.680 1.00 44.05 ? 341 GLU A OE2 1 ATOM 2294 N N . ASP A 1 289 ? -19.254 27.067 -12.527 1.00 37.86 ? 342 ASP A N 1 ATOM 2295 C CA . ASP A 1 289 ? -18.619 28.327 -12.162 1.00 37.82 ? 342 ASP A CA 1 ATOM 2296 C C . ASP A 1 289 ? -18.389 28.403 -10.661 1.00 36.76 ? 342 ASP A C 1 ATOM 2297 O O . ASP A 1 289 ? -19.230 27.968 -9.874 1.00 35.31 ? 342 ASP A O 1 ATOM 2298 C CB . ASP A 1 289 ? -19.489 29.498 -12.591 1.00 38.94 ? 342 ASP A CB 1 ATOM 2299 C CG . ASP A 1 289 ? -19.329 29.834 -14.050 1.00 38.96 ? 342 ASP A CG 1 ATOM 2300 O OD1 . ASP A 1 289 ? -18.406 29.293 -14.696 1.00 39.31 ? 342 ASP A OD1 1 ATOM 2301 O OD2 . ASP A 1 289 ? -20.082 30.634 -14.631 1.00 40.58 ? 342 ASP A OD2 1 ATOM 2302 N N . VAL A 1 290 ? -17.255 28.972 -10.270 1.00 36.27 ? 343 VAL A N 1 ATOM 2303 C CA . VAL A 1 290 ? -16.927 29.125 -8.855 1.00 35.37 ? 343 VAL A CA 1 ATOM 2304 C C . VAL A 1 290 ? -16.309 30.475 -8.590 1.00 35.81 ? 343 VAL A C 1 ATOM 2305 O O . VAL A 1 290 ? -15.456 30.937 -9.341 1.00 39.43 ? 343 VAL A O 1 ATOM 2306 C CB . VAL A 1 290 ? -15.947 28.058 -8.382 1.00 33.70 ? 343 VAL A CB 1 ATOM 2307 C CG1 . VAL A 1 290 ? -15.607 28.276 -6.920 1.00 35.84 ? 343 VAL A CG1 1 ATOM 2308 C CG2 . VAL A 1 290 ? -16.529 26.678 -8.594 1.00 33.23 ? 343 VAL A CG2 1 ATOM 2309 N N . VAL A 1 291 ? -16.739 31.115 -7.514 1.00 36.25 ? 344 VAL A N 1 ATOM 2310 C CA . VAL A 1 291 ? -16.154 32.386 -7.130 1.00 35.06 ? 344 VAL A CA 1 ATOM 2311 C C . VAL A 1 291 ? -15.038 32.130 -6.131 1.00 35.45 ? 344 VAL A C 1 ATOM 2312 O O . VAL A 1 291 ? -15.261 31.540 -5.077 1.00 36.91 ? 344 VAL A O 1 ATOM 2313 C CB . VAL A 1 291 ? -17.196 33.319 -6.533 1.00 34.13 ? 344 VAL A CB 1 ATOM 2314 C CG1 . VAL A 1 291 ? -16.530 34.586 -5.980 1.00 35.09 ? 344 VAL A CG1 1 ATOM 2315 C CG2 . VAL A 1 291 ? -18.247 33.658 -7.582 1.00 33.03 ? 344 VAL A CG2 1 ATOM 2316 N N . VAL A 1 292 ? -13.833 32.555 -6.489 1.00 35.54 ? 345 VAL A N 1 ATOM 2317 C CA . VAL A 1 292 ? -12.639 32.230 -5.723 1.00 36.14 ? 345 VAL A CA 1 ATOM 2318 C C . VAL A 1 292 ? -12.110 33.458 -5.008 1.00 33.87 ? 345 VAL A C 1 ATOM 2319 O O . VAL A 1 292 ? -11.619 34.379 -5.643 1.00 34.66 ? 345 VAL A O 1 ATOM 2320 C CB . VAL A 1 292 ? -11.528 31.717 -6.637 1.00 36.80 ? 345 VAL A CB 1 ATOM 2321 C CG1 . VAL A 1 292 ? -10.174 31.992 -6.019 1.00 36.57 ? 345 VAL A CG1 1 ATOM 2322 C CG2 . VAL A 1 292 ? -11.719 30.232 -6.925 1.00 36.87 ? 345 VAL A CG2 1 ATOM 2323 N N . TYR A 1 293 ? -12.202 33.459 -3.683 1.00 32.96 ? 346 TYR A N 1 ATOM 2324 C CA . TYR A 1 293 ? -11.858 34.630 -2.885 1.00 32.62 ? 346 TYR A CA 1 ATOM 2325 C C . TYR A 1 293 ? -10.368 34.667 -2.520 1.00 30.41 ? 346 TYR A C 1 ATOM 2326 O O . TYR A 1 293 ? -9.868 35.686 -2.043 1.00 30.65 ? 346 TYR A O 1 ATOM 2327 C CB . TYR A 1 293 ? -12.675 34.634 -1.592 1.00 33.25 ? 346 TYR A CB 1 ATOM 2328 C CG . TYR A 1 293 ? -14.046 35.269 -1.692 1.00 33.09 ? 346 TYR A CG 1 ATOM 2329 C CD1 . TYR A 1 293 ? -14.354 36.157 -2.710 1.00 32.96 ? 346 TYR A CD1 1 ATOM 2330 C CD2 . TYR A 1 293 ? -15.034 34.988 -0.742 1.00 33.03 ? 346 TYR A CD2 1 ATOM 2331 C CE1 . TYR A 1 293 ? -15.607 36.741 -2.796 1.00 31.34 ? 346 TYR A CE1 1 ATOM 2332 C CE2 . TYR A 1 293 ? -16.287 35.572 -0.815 1.00 31.94 ? 346 TYR A CE2 1 ATOM 2333 C CZ . TYR A 1 293 ? -16.571 36.443 -1.853 1.00 31.58 ? 346 TYR A CZ 1 ATOM 2334 O OH . TYR A 1 293 ? -17.813 37.031 -1.942 1.00 29.62 ? 346 TYR A OH 1 ATOM 2335 N N . ALA A 1 294 ? -9.667 33.555 -2.709 1.00 28.06 ? 347 ALA A N 1 ATOM 2336 C CA . ALA A 1 294 ? -8.390 33.339 -2.028 1.00 26.24 ? 347 ALA A CA 1 ATOM 2337 C C . ALA A 1 294 ? -7.397 32.599 -2.935 1.00 25.40 ? 347 ALA A C 1 ATOM 2338 O O . ALA A 1 294 ? -6.729 31.640 -2.522 1.00 19.47 ? 347 ALA A O 1 ATOM 2339 C CB . ALA A 1 294 ? -8.613 32.569 -0.740 1.00 25.84 ? 347 ALA A CB 1 ATOM 2340 N N . PRO A 1 295 ? -7.303 33.067 -4.173 1.00 25.81 ? 348 PRO A N 1 ATOM 2341 C CA . PRO A 1 295 ? -6.385 32.494 -5.159 1.00 27.91 ? 348 PRO A CA 1 ATOM 2342 C C . PRO A 1 295 ? -4.972 32.343 -4.613 1.00 27.58 ? 348 PRO A C 1 ATOM 2343 O O . PRO A 1 295 ? -4.380 31.269 -4.721 1.00 27.06 ? 348 PRO A O 1 ATOM 2344 C CB . PRO A 1 295 ? -6.411 33.512 -6.305 1.00 28.02 ? 348 PRO A CB 1 ATOM 2345 C CG . PRO A 1 295 ? -7.156 34.704 -5.781 1.00 27.58 ? 348 PRO A CG 1 ATOM 2346 C CD . PRO A 1 295 ? -8.056 34.212 -4.707 1.00 26.98 ? 348 PRO A CD 1 ATOM 2347 N N . GLU A 1 296 ? -4.436 33.404 -4.022 1.00 27.38 ? 349 GLU A N 1 ATOM 2348 C CA . GLU A 1 296 ? -3.047 33.388 -3.600 1.00 31.36 ? 349 GLU A CA 1 ATOM 2349 C C . GLU A 1 296 ? -2.846 32.355 -2.511 1.00 30.50 ? 349 GLU A C 1 ATOM 2350 O O . GLU A 1 296 ? -1.791 31.715 -2.429 1.00 30.83 ? 349 GLU A O 1 ATOM 2351 C CB . GLU A 1 296 ? -2.642 34.758 -3.098 1.00 35.45 ? 349 GLU A CB 1 ATOM 2352 C CG . GLU A 1 296 ? -3.647 35.820 -3.490 1.00 41.32 ? 349 GLU A CG 1 ATOM 2353 C CD . GLU A 1 296 ? -2.982 37.052 -4.035 1.00 43.93 ? 349 GLU A CD 1 ATOM 2354 O OE1 . GLU A 1 296 ? -3.667 37.835 -4.730 1.00 45.05 ? 349 GLU A OE1 1 ATOM 2355 O OE2 . GLU A 1 296 ? -1.776 37.228 -3.754 1.00 46.35 ? 349 GLU A OE2 1 ATOM 2356 N N . TYR A 1 297 ? -3.864 32.189 -1.677 1.00 25.96 ? 350 TYR A N 1 ATOM 2357 C CA . TYR A 1 297 ? -3.762 31.287 -0.554 1.00 24.31 ? 350 TYR A CA 1 ATOM 2358 C C . TYR A 1 297 ? -3.697 29.870 -1.079 1.00 24.52 ? 350 TYR A C 1 ATOM 2359 O O . TYR A 1 297 ? -2.949 29.039 -0.559 1.00 27.04 ? 350 TYR A O 1 ATOM 2360 C CB . TYR A 1 297 ? -4.957 31.461 0.381 1.00 23.29 ? 350 TYR A CB 1 ATOM 2361 C CG . TYR A 1 297 ? -5.192 30.297 1.309 1.00 22.32 ? 350 TYR A CG 1 ATOM 2362 C CD1 . TYR A 1 297 ? -6.200 29.398 1.059 1.00 22.22 ? 350 TYR A CD1 1 ATOM 2363 C CD2 . TYR A 1 297 ? -4.410 30.112 2.439 1.00 23.07 ? 350 TYR A CD2 1 ATOM 2364 C CE1 . TYR A 1 297 ? -6.428 28.335 1.899 1.00 21.77 ? 350 TYR A CE1 1 ATOM 2365 C CE2 . TYR A 1 297 ? -4.625 29.053 3.287 1.00 24.38 ? 350 TYR A CE2 1 ATOM 2366 C CZ . TYR A 1 297 ? -5.642 28.166 3.015 1.00 23.51 ? 350 TYR A CZ 1 ATOM 2367 O OH . TYR A 1 297 ? -5.853 27.110 3.867 1.00 24.68 ? 350 TYR A OH 1 ATOM 2368 N N . LEU A 1 298 ? -4.478 29.597 -2.115 1.00 25.68 ? 351 LEU A N 1 ATOM 2369 C CA . LEU A 1 298 ? -4.472 28.282 -2.740 1.00 30.06 ? 351 LEU A CA 1 ATOM 2370 C C . LEU A 1 298 ? -3.105 27.993 -3.344 1.00 31.65 ? 351 LEU A C 1 ATOM 2371 O O . LEU A 1 298 ? -2.473 26.987 -3.022 1.00 30.92 ? 351 LEU A O 1 ATOM 2372 C CB . LEU A 1 298 ? -5.550 28.193 -3.816 1.00 30.46 ? 351 LEU A CB 1 ATOM 2373 C CG . LEU A 1 298 ? -6.989 28.141 -3.301 1.00 30.63 ? 351 LEU A CG 1 ATOM 2374 C CD1 . LEU A 1 298 ? -7.961 28.046 -4.466 1.00 31.90 ? 351 LEU A CD1 1 ATOM 2375 C CD2 . LEU A 1 298 ? -7.186 26.978 -2.346 1.00 29.15 ? 351 LEU A CD2 1 ATOM 2376 N N . THR A 1 299 ? -2.648 28.890 -4.211 1.00 33.96 ? 352 THR A N 1 ATOM 2377 C CA . THR A 1 299 ? -1.264 28.879 -4.666 1.00 35.63 ? 352 THR A CA 1 ATOM 2378 C C . THR A 1 299 ? -0.351 28.465 -3.521 1.00 34.55 ? 352 THR A C 1 ATOM 2379 O O . THR A 1 299 ? 0.340 27.437 -3.593 1.00 34.67 ? 352 THR A O 1 ATOM 2380 C CB . THR A 1 299 ? -0.872 30.267 -5.183 1.00 37.86 ? 352 THR A CB 1 ATOM 2381 O OG1 . THR A 1 299 ? -1.785 30.671 -6.216 1.00 39.79 ? 352 THR A OG1 1 ATOM 2382 C CG2 . THR A 1 299 ? 0.492 30.230 -5.876 1.00 39.27 ? 352 THR A CG2 1 ATOM 2383 N N . LYS A 1 300 ? -0.366 29.253 -2.452 1.00 31.89 ? 353 LYS A N 1 ATOM 2384 C CA . LYS A 1 300 ? 0.629 29.111 -1.397 1.00 30.53 ? 353 LYS A CA 1 ATOM 2385 C C . LYS A 1 300 ? 0.467 27.775 -0.691 1.00 30.62 ? 353 LYS A C 1 ATOM 2386 O O . LYS A 1 300 ? 1.403 27.264 -0.090 1.00 27.94 ? 353 LYS A O 1 ATOM 2387 C CB . LYS A 1 300 ? 0.497 30.242 -0.388 1.00 30.07 ? 353 LYS A CB 1 ATOM 2388 C CG . LYS A 1 300 ? 1.090 31.556 -0.845 1.00 28.48 ? 353 LYS A CG 1 ATOM 2389 C CD . LYS A 1 300 ? 0.533 32.692 -0.019 1.00 28.62 ? 353 LYS A CD 1 ATOM 2390 C CE . LYS A 1 300 ? 1.339 33.950 -0.192 1.00 29.42 ? 353 LYS A CE 1 ATOM 2391 N NZ . LYS A 1 300 ? 0.860 35.036 0.711 1.00 31.52 ? 353 LYS A NZ 1 ATOM 2392 N N . LEU A 1 301 ? -0.737 27.221 -0.768 1.00 32.10 ? 354 LEU A N 1 ATOM 2393 C CA . LEU A 1 301 ? -1.077 25.999 -0.048 1.00 33.70 ? 354 LEU A CA 1 ATOM 2394 C C . LEU A 1 301 ? -0.281 24.806 -0.563 1.00 34.36 ? 354 LEU A C 1 ATOM 2395 O O . LEU A 1 301 ? 0.088 23.924 0.204 1.00 36.34 ? 354 LEU A O 1 ATOM 2396 C CB . LEU A 1 301 ? -2.571 25.719 -0.188 1.00 34.28 ? 354 LEU A CB 1 ATOM 2397 C CG . LEU A 1 301 ? -3.271 25.168 1.050 1.00 35.85 ? 354 LEU A CG 1 ATOM 2398 C CD1 . LEU A 1 301 ? -2.467 25.422 2.313 1.00 34.56 ? 354 LEU A CD1 1 ATOM 2399 C CD2 . LEU A 1 301 ? -4.672 25.751 1.170 1.00 37.49 ? 354 LEU A CD2 1 ATOM 2400 N N . LYS A 1 302 ? -0.023 24.787 -1.869 1.00 34.54 ? 355 LYS A N 1 ATOM 2401 C CA . LYS A 1 302 ? 0.549 23.620 -2.530 1.00 32.99 ? 355 LYS A CA 1 ATOM 2402 C C . LYS A 1 302 ? 1.793 23.099 -1.815 1.00 33.60 ? 355 LYS A C 1 ATOM 2403 O O . LYS A 1 302 ? 1.805 21.966 -1.336 1.00 34.12 ? 355 LYS A O 1 ATOM 2404 C CB . LYS A 1 302 ? 0.884 23.946 -3.988 1.00 33.33 ? 355 LYS A CB 1 ATOM 2405 C CG . LYS A 1 302 ? 1.060 22.720 -4.859 1.00 34.18 ? 355 LYS A CG 1 ATOM 2406 C CD . LYS A 1 302 ? 1.848 23.030 -6.120 1.00 35.39 ? 355 LYS A CD 1 ATOM 2407 C CE . LYS A 1 302 ? 1.495 22.078 -7.255 1.00 35.93 ? 355 LYS A CE 1 ATOM 2408 N NZ . LYS A 1 302 ? 0.902 22.785 -8.429 1.00 36.22 ? 355 LYS A NZ 1 ATOM 2409 N N . PRO A 1 303 ? 2.846 23.911 -1.747 1.00 33.98 ? 356 PRO A N 1 ATOM 2410 C CA . PRO A 1 303 ? 4.105 23.465 -1.143 1.00 35.62 ? 356 PRO A CA 1 ATOM 2411 C C . PRO A 1 303 ? 3.939 23.115 0.333 1.00 36.85 ? 356 PRO A C 1 ATOM 2412 O O . PRO A 1 303 ? 4.681 22.284 0.857 1.00 41.87 ? 356 PRO A O 1 ATOM 2413 C CB . PRO A 1 303 ? 5.044 24.672 -1.328 1.00 35.22 ? 356 PRO A CB 1 ATOM 2414 C CG . PRO A 1 303 ? 4.165 25.831 -1.596 1.00 33.40 ? 356 PRO A CG 1 ATOM 2415 C CD . PRO A 1 303 ? 2.930 25.290 -2.249 1.00 33.60 ? 356 PRO A CD 1 ATOM 2416 N N . ILE A 1 304 ? 2.963 23.729 0.992 1.00 36.67 ? 357 ILE A N 1 ATOM 2417 C CA . ILE A 1 304 ? 2.736 23.467 2.407 1.00 35.52 ? 357 ILE A CA 1 ATOM 2418 C C . ILE A 1 304 ? 2.231 22.048 2.577 1.00 35.05 ? 357 ILE A C 1 ATOM 2419 O O . ILE A 1 304 ? 2.796 21.240 3.318 1.00 34.86 ? 357 ILE A O 1 ATOM 2420 C CB . ILE A 1 304 ? 1.697 24.443 2.975 1.00 35.16 ? 357 ILE A CB 1 ATOM 2421 C CG1 . ILE A 1 304 ? 2.228 25.880 2.947 1.00 35.22 ? 357 ILE A CG1 1 ATOM 2422 C CG2 . ILE A 1 304 ? 1.320 24.034 4.388 1.00 34.53 ? 357 ILE A CG2 1 ATOM 2423 C CD1 . ILE A 1 304 ? 1.885 26.632 1.676 1.00 37.04 ? 357 ILE A CD1 1 ATOM 2424 N N . LEU A 1 305 ? 1.146 21.758 1.876 1.00 36.14 ? 358 LEU A N 1 ATOM 2425 C CA . LEU A 1 305 ? 0.439 20.501 2.044 1.00 35.42 ? 358 LEU A CA 1 ATOM 2426 C C . LEU A 1 305 ? 1.356 19.319 1.725 1.00 35.47 ? 358 LEU A C 1 ATOM 2427 O O . LEU A 1 305 ? 1.397 18.343 2.467 1.00 35.34 ? 358 LEU A O 1 ATOM 2428 C CB . LEU A 1 305 ? -0.798 20.492 1.150 1.00 36.37 ? 358 LEU A CB 1 ATOM 2429 C CG . LEU A 1 305 ? -2.093 20.984 1.805 1.00 36.57 ? 358 LEU A CG 1 ATOM 2430 C CD1 . LEU A 1 305 ? -1.820 22.093 2.798 1.00 37.43 ? 358 LEU A CD1 1 ATOM 2431 C CD2 . LEU A 1 305 ? -3.106 21.435 0.756 1.00 35.78 ? 358 LEU A CD2 1 ATOM 2432 N N . THR A 1 306 ? 2.114 19.430 0.637 1.00 37.84 ? 359 THR A N 1 ATOM 2433 C CA . THR A 1 306 ? 2.936 18.324 0.154 1.00 39.87 ? 359 THR A CA 1 ATOM 2434 C C . THR A 1 306 ? 3.880 17.814 1.233 1.00 39.90 ? 359 THR A C 1 ATOM 2435 O O . THR A 1 306 ? 4.578 16.819 1.038 1.00 40.83 ? 359 THR A O 1 ATOM 2436 C CB . THR A 1 306 ? 3.772 18.751 -1.054 1.00 42.32 ? 359 THR A CB 1 ATOM 2437 O OG1 . THR A 1 306 ? 5.068 19.181 -0.611 1.00 45.05 ? 359 THR A OG1 1 ATOM 2438 C CG2 . THR A 1 306 ? 3.183 19.986 -1.719 1.00 44.01 ? 359 THR A CG2 1 ATOM 2439 N N . LYS A 1 307 ? 3.919 18.508 2.363 1.00 39.61 ? 360 LYS A N 1 ATOM 2440 C CA . LYS A 1 307 ? 5.032 18.366 3.289 1.00 39.06 ? 360 LYS A CA 1 ATOM 2441 C C . LYS A 1 307 ? 4.607 17.609 4.536 1.00 38.74 ? 360 LYS A C 1 ATOM 2442 O O . LYS A 1 307 ? 5.437 17.283 5.384 1.00 39.73 ? 360 LYS A O 1 ATOM 2443 C CB . LYS A 1 307 ? 5.582 19.738 3.685 1.00 40.54 ? 360 LYS A CB 1 ATOM 2444 C CG . LYS A 1 307 ? 6.526 20.366 2.660 1.00 41.27 ? 360 LYS A CG 1 ATOM 2445 C CD . LYS A 1 307 ? 7.305 21.539 3.248 1.00 41.30 ? 360 LYS A CD 1 ATOM 2446 C CE . LYS A 1 307 ? 6.556 22.184 4.412 1.00 41.19 ? 360 LYS A CE 1 ATOM 2447 N NZ . LYS A 1 307 ? 6.953 23.607 4.625 1.00 39.17 ? 360 LYS A NZ 1 ATOM 2448 N N . TYR A 1 308 ? 3.310 17.341 4.657 1.00 35.48 ? 361 TYR A N 1 ATOM 2449 C CA . TYR A 1 308 ? 2.763 16.801 5.895 1.00 33.29 ? 361 TYR A CA 1 ATOM 2450 C C . TYR A 1 308 ? 2.073 15.469 5.617 1.00 33.17 ? 361 TYR A C 1 ATOM 2451 O O . TYR A 1 308 ? 1.661 15.211 4.498 1.00 33.05 ? 361 TYR A O 1 ATOM 2452 C CB . TYR A 1 308 ? 1.788 17.799 6.532 1.00 29.38 ? 361 TYR A CB 1 ATOM 2453 C CG . TYR A 1 308 ? 2.464 18.978 7.184 1.00 24.64 ? 361 TYR A CG 1 ATOM 2454 C CD1 . TYR A 1 308 ? 2.885 18.920 8.499 1.00 24.27 ? 361 TYR A CD1 1 ATOM 2455 C CD2 . TYR A 1 308 ? 2.684 20.148 6.485 1.00 26.29 ? 361 TYR A CD2 1 ATOM 2456 C CE1 . TYR A 1 308 ? 3.513 19.990 9.099 1.00 23.51 ? 361 TYR A CE1 1 ATOM 2457 C CE2 . TYR A 1 308 ? 3.303 21.235 7.086 1.00 25.42 ? 361 TYR A CE2 1 ATOM 2458 C CZ . TYR A 1 308 ? 3.715 21.146 8.391 1.00 23.84 ? 361 TYR A CZ 1 ATOM 2459 O OH . TYR A 1 308 ? 4.332 22.222 8.992 1.00 24.61 ? 361 TYR A OH 1 ATOM 2460 N N . SER A 1 309 ? 1.962 14.612 6.624 1.00 34.85 ? 362 SER A N 1 ATOM 2461 C CA . SER A 1 309 ? 1.223 13.367 6.444 1.00 36.49 ? 362 SER A CA 1 ATOM 2462 C C . SER A 1 309 ? -0.278 13.630 6.333 1.00 37.60 ? 362 SER A C 1 ATOM 2463 O O . SER A 1 309 ? -0.759 14.715 6.668 1.00 37.81 ? 362 SER A O 1 ATOM 2464 C CB . SER A 1 309 ? 1.498 12.399 7.591 1.00 35.62 ? 362 SER A CB 1 ATOM 2465 O OG . SER A 1 309 ? 1.547 13.090 8.820 1.00 37.40 ? 362 SER A OG 1 ATOM 2466 N N . ALA A 1 310 ? -1.004 12.627 5.847 1.00 36.30 ? 363 ALA A N 1 ATOM 2467 C CA . ALA A 1 310 ? -2.434 12.494 6.100 1.00 35.87 ? 363 ALA A CA 1 ATOM 2468 C C . ALA A 1 310 ? -2.751 12.519 7.598 1.00 34.71 ? 363 ALA A C 1 ATOM 2469 O O . ALA A 1 310 ? -3.768 13.066 8.021 1.00 33.80 ? 363 ALA A O 1 ATOM 2470 C CB . ALA A 1 310 ? -2.948 11.208 5.476 1.00 36.18 ? 363 ALA A CB 1 ATOM 2471 N N . ARG A 1 311 ? -1.874 11.924 8.391 1.00 31.52 ? 364 ARG A N 1 ATOM 2472 C CA . ARG A 1 311 ? -2.025 11.919 9.832 1.00 31.60 ? 364 ARG A CA 1 ATOM 2473 C C . ARG A 1 311 ? -1.919 13.336 10.395 1.00 33.84 ? 364 ARG A C 1 ATOM 2474 O O . ARG A 1 311 ? -2.756 13.767 11.194 1.00 30.31 ? 364 ARG A O 1 ATOM 2475 C CB . ARG A 1 311 ? -0.952 11.028 10.445 1.00 31.61 ? 364 ARG A CB 1 ATOM 2476 C CG . ARG A 1 311 ? -0.704 11.264 11.911 1.00 34.19 ? 364 ARG A CG 1 ATOM 2477 C CD . ARG A 1 311 ? 0.104 10.163 12.588 1.00 34.20 ? 364 ARG A CD 1 ATOM 2478 N NE . ARG A 1 311 ? -0.301 10.030 13.977 1.00 38.24 ? 364 ARG A NE 1 ATOM 2479 C CZ . ARG A 1 311 ? -0.980 9.003 14.463 1.00 39.64 ? 364 ARG A CZ 1 ATOM 2480 N NH1 . ARG A 1 311 ? -1.311 7.987 13.673 1.00 41.70 ? 364 ARG A NH1 1 ATOM 2481 N NH2 . ARG A 1 311 ? -1.322 8.987 15.744 1.00 38.68 ? 364 ARG A NH2 1 ATOM 2482 N N . ASP A 1 312 ? -0.890 14.064 9.975 1.00 33.87 ? 365 ASP A N 1 ATOM 2483 C CA . ASP A 1 312 ? -0.728 15.433 10.419 1.00 32.26 ? 365 ASP A CA 1 ATOM 2484 C C . ASP A 1 312 ? -1.984 16.206 10.034 1.00 31.56 ? 365 ASP A C 1 ATOM 2485 O O . ASP A 1 312 ? -2.561 16.925 10.849 1.00 28.84 ? 365 ASP A O 1 ATOM 2486 C CB . ASP A 1 312 ? 0.502 16.075 9.782 1.00 31.72 ? 365 ASP A CB 1 ATOM 2487 C CG . ASP A 1 312 ? 1.790 15.354 10.124 1.00 32.00 ? 365 ASP A CG 1 ATOM 2488 O OD1 . ASP A 1 312 ? 1.916 14.825 11.254 1.00 30.82 ? 365 ASP A OD1 1 ATOM 2489 O OD2 . ASP A 1 312 ? 2.742 15.283 9.313 1.00 33.22 ? 365 ASP A OD2 1 ATOM 2490 N N . LEU A 1 313 ? -2.406 16.046 8.785 1.00 32.00 ? 366 LEU A N 1 ATOM 2491 C CA . LEU A 1 313 ? -3.483 16.861 8.241 1.00 32.03 ? 366 LEU A CA 1 ATOM 2492 C C . LEU A 1 313 ? -4.739 16.606 9.056 1.00 31.28 ? 366 LEU A C 1 ATOM 2493 O O . LEU A 1 313 ? -5.434 17.538 9.457 1.00 31.74 ? 366 LEU A O 1 ATOM 2494 C CB . LEU A 1 313 ? -3.731 16.530 6.772 1.00 30.92 ? 366 LEU A CB 1 ATOM 2495 C CG . LEU A 1 313 ? -2.596 16.887 5.808 1.00 32.74 ? 366 LEU A CG 1 ATOM 2496 C CD1 . LEU A 1 313 ? -2.876 16.321 4.419 1.00 32.80 ? 366 LEU A CD1 1 ATOM 2497 C CD2 . LEU A 1 313 ? -2.394 18.388 5.727 1.00 31.04 ? 366 LEU A CD2 1 ATOM 2498 N N . GLN A 1 314 ? -5.013 15.332 9.315 1.00 29.77 ? 367 GLN A N 1 ATOM 2499 C CA . GLN A 1 314 ? -6.280 14.943 9.908 1.00 29.95 ? 367 GLN A CA 1 ATOM 2500 C C . GLN A 1 314 ? -6.269 15.294 11.371 1.00 26.48 ? 367 GLN A C 1 ATOM 2501 O O . GLN A 1 314 ? -7.316 15.472 11.983 1.00 29.28 ? 367 GLN A O 1 ATOM 2502 C CB . GLN A 1 314 ? -6.524 13.441 9.760 1.00 30.44 ? 367 GLN A CB 1 ATOM 2503 C CG . GLN A 1 314 ? -7.906 13.026 10.216 1.00 30.94 ? 367 GLN A CG 1 ATOM 2504 C CD . GLN A 1 314 ? -8.999 13.701 9.407 1.00 30.94 ? 367 GLN A CD 1 ATOM 2505 O OE1 . GLN A 1 314 ? -8.980 13.655 8.179 1.00 32.37 ? 367 GLN A OE1 1 ATOM 2506 N NE2 . GLN A 1 314 ? -9.943 14.340 10.090 1.00 29.71 ? 367 GLN A NE2 1 ATOM 2507 N N . ASN A 1 315 ? -5.077 15.365 11.937 1.00 26.70 ? 368 ASN A N 1 ATOM 2508 C CA . ASN A 1 315 ? -4.916 15.739 13.332 1.00 27.72 ? 368 ASN A CA 1 ATOM 2509 C C . ASN A 1 315 ? -5.295 17.203 13.560 1.00 28.65 ? 368 ASN A C 1 ATOM 2510 O O . ASN A 1 315 ? -5.940 17.539 14.545 1.00 29.07 ? 368 ASN A O 1 ATOM 2511 C CB . ASN A 1 315 ? -3.478 15.504 13.770 1.00 27.57 ? 368 ASN A CB 1 ATOM 2512 C CG . ASN A 1 315 ? -3.318 14.259 14.635 1.00 27.91 ? 368 ASN A CG 1 ATOM 2513 O OD1 . ASN A 1 315 ? -2.216 13.955 15.095 1.00 28.44 ? 368 ASN A OD1 1 ATOM 2514 N ND2 . ASN A 1 315 ? -4.409 13.540 14.861 1.00 26.31 ? 368 ASN A ND2 1 ATOM 2515 N N . LEU A 1 316 ? -4.901 18.068 12.637 1.00 29.93 ? 369 LEU A N 1 ATOM 2516 C CA . LEU A 1 316 ? -5.365 19.451 12.651 1.00 27.82 ? 369 LEU A CA 1 ATOM 2517 C C . LEU A 1 316 ? -6.846 19.500 12.309 1.00 28.21 ? 369 LEU A C 1 ATOM 2518 O O . LEU A 1 316 ? -7.619 20.197 12.956 1.00 26.98 ? 369 LEU A O 1 ATOM 2519 C CB . LEU A 1 316 ? -4.575 20.289 11.650 1.00 25.06 ? 369 LEU A CB 1 ATOM 2520 C CG . LEU A 1 316 ? -5.230 21.604 11.251 1.00 24.63 ? 369 LEU A CG 1 ATOM 2521 C CD1 . LEU A 1 316 ? -5.599 22.398 12.496 1.00 24.76 ? 369 LEU A CD1 1 ATOM 2522 C CD2 . LEU A 1 316 ? -4.310 22.416 10.336 1.00 24.35 ? 369 LEU A CD2 1 ATOM 2523 N N . MET A 1 317 ? -7.241 18.764 11.278 1.00 29.72 ? 370 MET A N 1 ATOM 2524 C CA . MET A 1 317 ? -8.573 18.923 10.711 1.00 28.47 ? 370 MET A CA 1 ATOM 2525 C C . MET A 1 317 ? -9.638 18.567 11.734 1.00 27.05 ? 370 MET A C 1 ATOM 2526 O O . MET A 1 317 ? -10.621 19.302 11.889 1.00 22.48 ? 370 MET A O 1 ATOM 2527 C CB . MET A 1 317 ? -8.734 18.071 9.457 1.00 30.88 ? 370 MET A CB 1 ATOM 2528 C CG . MET A 1 317 ? -8.560 18.879 8.177 1.00 34.00 ? 370 MET A CG 1 ATOM 2529 S SD . MET A 1 317 ? -8.770 17.886 6.699 1.00 37.63 ? 370 MET A SD 1 ATOM 2530 C CE . MET A 1 317 ? -7.532 16.674 7.000 1.00 36.25 ? 370 MET A CE 1 ATOM 2531 N N . SER A 1 318 ? -9.428 17.459 12.446 1.00 24.02 ? 371 SER A N 1 ATOM 2532 C CA . SER A 1 318 ? -10.404 16.974 13.420 1.00 25.16 ? 371 SER A CA 1 ATOM 2533 C C . SER A 1 318 ? -10.429 17.859 14.660 1.00 24.48 ? 371 SER A C 1 ATOM 2534 O O . SER A 1 318 ? -11.490 18.117 15.213 1.00 26.51 ? 371 SER A O 1 ATOM 2535 C CB . SER A 1 318 ? -10.104 15.525 13.840 1.00 25.29 ? 371 SER A CB 1 ATOM 2536 O OG . SER A 1 318 ? -10.359 14.599 12.794 1.00 26.36 ? 371 SER A OG 1 ATOM 2537 N N . TRP A 1 319 ? -9.254 18.304 15.102 1.00 25.13 ? 372 TRP A N 1 ATOM 2538 C CA . TRP A 1 319 ? -9.136 19.163 16.284 1.00 23.95 ? 372 TRP A CA 1 ATOM 2539 C C . TRP A 1 319 ? -9.887 20.470 16.140 1.00 20.55 ? 372 TRP A C 1 ATOM 2540 O O . TRP A 1 319 ? -10.254 21.090 17.135 1.00 20.40 ? 372 TRP A O 1 ATOM 2541 C CB . TRP A 1 319 ? -7.665 19.488 16.578 1.00 22.22 ? 372 TRP A CB 1 ATOM 2542 C CG . TRP A 1 319 ? -7.476 20.699 17.494 1.00 22.36 ? 372 TRP A CG 1 ATOM 2543 C CD1 . TRP A 1 319 ? -6.901 21.895 17.161 1.00 21.01 ? 372 TRP A CD1 1 ATOM 2544 C CD2 . TRP A 1 319 ? -7.870 20.822 18.875 1.00 19.49 ? 372 TRP A CD2 1 ATOM 2545 N NE1 . TRP A 1 319 ? -6.907 22.745 18.242 1.00 21.37 ? 372 TRP A NE1 1 ATOM 2546 C CE2 . TRP A 1 319 ? -7.500 22.115 19.305 1.00 22.10 ? 372 TRP A CE2 1 ATOM 2547 C CE3 . TRP A 1 319 ? -8.490 19.969 19.792 1.00 20.59 ? 372 TRP A CE3 1 ATOM 2548 C CZ2 . TRP A 1 319 ? -7.721 22.567 20.608 1.00 20.33 ? 372 TRP A CZ2 1 ATOM 2549 C CZ3 . TRP A 1 319 ? -8.715 20.418 21.082 1.00 22.52 ? 372 TRP A CZ3 1 ATOM 2550 C CH2 . TRP A 1 319 ? -8.333 21.711 21.481 1.00 20.49 ? 372 TRP A CH2 1 ATOM 2551 N N . ARG A 1 320 ? -10.066 20.914 14.903 1.00 22.40 ? 373 ARG A N 1 ATOM 2552 C CA . ARG A 1 320 ? -10.683 22.209 14.660 1.00 23.39 ? 373 ARG A CA 1 ATOM 2553 C C . ARG A 1 320 ? -12.207 22.111 14.823 1.00 23.41 ? 373 ARG A C 1 ATOM 2554 O O . ARG A 1 320 ? -12.875 23.113 15.099 1.00 19.60 ? 373 ARG A O 1 ATOM 2555 C CB . ARG A 1 320 ? -10.325 22.721 13.265 1.00 23.68 ? 373 ARG A CB 1 ATOM 2556 C CG . ARG A 1 320 ? -8.912 23.278 13.156 1.00 24.08 ? 373 ARG A CG 1 ATOM 2557 C CD . ARG A 1 320 ? -8.741 24.691 13.729 1.00 24.89 ? 373 ARG A CD 1 ATOM 2558 N NE . ARG A 1 320 ? -9.495 25.695 12.983 1.00 23.62 ? 373 ARG A NE 1 ATOM 2559 C CZ . ARG A 1 320 ? -10.619 26.245 13.406 1.00 22.38 ? 373 ARG A CZ 1 ATOM 2560 N NH1 . ARG A 1 320 ? -11.127 25.892 14.577 1.00 25.48 ? 373 ARG A NH1 1 ATOM 2561 N NH2 . ARG A 1 320 ? -11.245 27.138 12.658 1.00 21.09 ? 373 ARG A NH2 1 ATOM 2562 N N . PHE A 1 321 ? -12.737 20.901 14.649 1.00 21.99 ? 374 PHE A N 1 ATOM 2563 C CA . PHE A 1 321 ? -14.122 20.587 15.003 1.00 22.26 ? 374 PHE A CA 1 ATOM 2564 C C . PHE A 1 321 ? -14.257 20.286 16.495 1.00 22.05 ? 374 PHE A C 1 ATOM 2565 O O . PHE A 1 321 ? -15.114 20.850 17.178 1.00 20.95 ? 374 PHE A O 1 ATOM 2566 C CB . PHE A 1 321 ? -14.591 19.376 14.182 1.00 22.23 ? 374 PHE A CB 1 ATOM 2567 C CG . PHE A 1 321 ? -16.062 19.088 14.291 1.00 22.30 ? 374 PHE A CG 1 ATOM 2568 C CD1 . PHE A 1 321 ? -16.984 20.114 14.498 1.00 25.74 ? 374 PHE A CD1 1 ATOM 2569 C CD2 . PHE A 1 321 ? -16.527 17.795 14.185 1.00 21.77 ? 374 PHE A CD2 1 ATOM 2570 C CE1 . PHE A 1 321 ? -18.343 19.836 14.593 1.00 23.75 ? 374 PHE A CE1 1 ATOM 2571 C CE2 . PHE A 1 321 ? -17.879 17.513 14.282 1.00 20.86 ? 374 PHE A CE2 1 ATOM 2572 C CZ . PHE A 1 321 ? -18.785 18.530 14.492 1.00 22.67 ? 374 PHE A CZ 1 ATOM 2573 N N . ILE A 1 322 ? -13.412 19.381 16.987 1.00 22.79 ? 375 ILE A N 1 ATOM 2574 C CA . ILE A 1 322 ? -13.375 19.023 18.410 1.00 24.40 ? 375 ILE A CA 1 ATOM 2575 C C . ILE A 1 322 ? -13.282 20.260 19.313 1.00 23.91 ? 375 ILE A C 1 ATOM 2576 O O . ILE A 1 322 ? -14.087 20.441 20.220 1.00 23.52 ? 375 ILE A O 1 ATOM 2577 C CB . ILE A 1 322 ? -12.181 18.063 18.672 1.00 25.91 ? 375 ILE A CB 1 ATOM 2578 C CG1 . ILE A 1 322 ? -12.182 16.932 17.645 1.00 27.32 ? 375 ILE A CG1 1 ATOM 2579 C CG2 . ILE A 1 322 ? -12.233 17.464 20.082 1.00 24.92 ? 375 ILE A CG2 1 ATOM 2580 C CD1 . ILE A 1 322 ? -11.704 15.611 18.204 1.00 28.04 ? 375 ILE A CD1 1 ATOM 2581 N N . MET A 1 323 ? -12.294 21.111 19.056 1.00 26.40 ? 376 MET A N 1 ATOM 2582 C CA . MET A 1 323 ? -12.292 22.473 19.593 1.00 28.38 ? 376 MET A CA 1 ATOM 2583 C C . MET A 1 323 ? -13.686 22.884 20.068 1.00 25.02 ? 376 MET A C 1 ATOM 2584 O O . MET A 1 323 ? -13.871 23.390 21.173 1.00 22.93 ? 376 MET A O 1 ATOM 2585 C CB . MET A 1 323 ? -11.854 23.449 18.504 1.00 28.92 ? 376 MET A CB 1 ATOM 2586 C CG . MET A 1 323 ? -10.399 23.856 18.552 1.00 29.11 ? 376 MET A CG 1 ATOM 2587 S SD . MET A 1 323 ? -10.166 25.490 17.816 1.00 33.67 ? 376 MET A SD 1 ATOM 2588 C CE . MET A 1 323 ? -10.531 26.551 19.222 1.00 30.83 ? 376 MET A CE 1 ATOM 2589 N N . ASP A 1 324 ? -14.662 22.715 19.191 1.00 26.41 ? 377 ASP A N 1 ATOM 2590 C CA . ASP A 1 324 ? -15.910 23.458 19.303 1.00 25.19 ? 377 ASP A CA 1 ATOM 2591 C C . ASP A 1 324 ? -16.973 22.636 19.998 1.00 23.21 ? 377 ASP A C 1 ATOM 2592 O O . ASP A 1 324 ? -18.051 23.151 20.272 1.00 25.95 ? 377 ASP A O 1 ATOM 2593 C CB . ASP A 1 324 ? -16.419 23.870 17.924 1.00 25.29 ? 377 ASP A CB 1 ATOM 2594 C CG . ASP A 1 324 ? -15.585 24.963 17.300 1.00 27.76 ? 377 ASP A CG 1 ATOM 2595 O OD1 . ASP A 1 324 ? -15.761 25.225 16.095 1.00 29.75 ? 377 ASP A OD1 1 ATOM 2596 O OD2 . ASP A 1 324 ? -14.716 25.605 17.929 1.00 31.76 ? 377 ASP A OD2 1 ATOM 2597 N N . LEU A 1 325 ? -16.667 21.368 20.269 1.00 21.17 ? 378 LEU A N 1 ATOM 2598 C CA . LEU A 1 325 ? -17.662 20.407 20.753 1.00 21.62 ? 378 LEU A CA 1 ATOM 2599 C C . LEU A 1 325 ? -17.529 20.222 22.254 1.00 23.66 ? 378 LEU A C 1 ATOM 2600 O O . LEU A 1 325 ? -18.464 19.800 22.942 1.00 25.04 ? 378 LEU A O 1 ATOM 2601 C CB . LEU A 1 325 ? -17.465 19.057 20.077 1.00 20.45 ? 378 LEU A CB 1 ATOM 2602 C CG . LEU A 1 325 ? -17.709 19.029 18.570 1.00 22.49 ? 378 LEU A CG 1 ATOM 2603 C CD1 . LEU A 1 325 ? -17.687 17.600 18.054 1.00 22.16 ? 378 LEU A CD1 1 ATOM 2604 C CD2 . LEU A 1 325 ? -19.034 19.701 18.237 1.00 21.54 ? 378 LEU A CD2 1 ATOM 2605 N N . VAL A 1 326 ? -16.348 20.513 22.761 1.00 22.10 ? 379 VAL A N 1 ATOM 2606 C CA . VAL A 1 326 ? -15.936 19.939 24.016 1.00 25.63 ? 379 VAL A CA 1 ATOM 2607 C C . VAL A 1 326 ? -16.661 20.665 25.149 1.00 25.79 ? 379 VAL A C 1 ATOM 2608 O O . VAL A 1 326 ? -16.837 20.128 26.231 1.00 23.80 ? 379 VAL A O 1 ATOM 2609 C CB . VAL A 1 326 ? -14.401 19.997 24.162 1.00 28.11 ? 379 VAL A CB 1 ATOM 2610 C CG1 . VAL A 1 326 ? -13.940 21.421 24.402 1.00 29.24 ? 379 VAL A CG1 1 ATOM 2611 C CG2 . VAL A 1 326 ? -13.936 19.075 25.273 1.00 30.73 ? 379 VAL A CG2 1 ATOM 2612 N N . SER A 1 327 ? -17.135 21.875 24.884 1.00 27.13 ? 380 SER A N 1 ATOM 2613 C CA . SER A 1 327 ? -17.910 22.590 25.886 1.00 28.78 ? 380 SER A CA 1 ATOM 2614 C C . SER A 1 327 ? -19.378 22.170 25.873 1.00 26.40 ? 380 SER A C 1 ATOM 2615 O O . SER A 1 327 ? -20.166 22.645 26.686 1.00 25.17 ? 380 SER A O 1 ATOM 2616 C CB . SER A 1 327 ? -17.774 24.107 25.706 1.00 29.12 ? 380 SER A CB 1 ATOM 2617 O OG . SER A 1 327 ? -18.810 24.632 24.895 1.00 31.14 ? 380 SER A OG 1 ATOM 2618 N N . SER A 1 328 ? -19.738 21.261 24.972 1.00 25.83 ? 381 SER A N 1 ATOM 2619 C CA . SER A 1 328 ? -21.061 20.640 25.005 1.00 26.34 ? 381 SER A CA 1 ATOM 2620 C C . SER A 1 328 ? -21.003 19.240 25.628 1.00 28.61 ? 381 SER A C 1 ATOM 2621 O O . SER A 1 328 ? -21.988 18.506 25.650 1.00 30.94 ? 381 SER A O 1 ATOM 2622 C CB . SER A 1 328 ? -21.643 20.560 23.599 1.00 26.09 ? 381 SER A CB 1 ATOM 2623 O OG . SER A 1 328 ? -21.424 21.761 22.877 1.00 28.51 ? 381 SER A OG 1 ATOM 2624 N N . LEU A 1 329 ? -19.836 18.872 26.133 1.00 29.80 ? 382 LEU A N 1 ATOM 2625 C CA . LEU A 1 329 ? -19.681 17.613 26.840 1.00 28.83 ? 382 LEU A CA 1 ATOM 2626 C C . LEU A 1 329 ? -19.655 17.852 28.339 1.00 29.07 ? 382 LEU A C 1 ATOM 2627 O O . LEU A 1 329 ? -19.992 18.937 28.816 1.00 30.06 ? 382 LEU A O 1 ATOM 2628 C CB . LEU A 1 329 ? -18.390 16.924 26.399 1.00 28.94 ? 382 LEU A CB 1 ATOM 2629 C CG . LEU A 1 329 ? -18.317 16.639 24.901 1.00 29.51 ? 382 LEU A CG 1 ATOM 2630 C CD1 . LEU A 1 329 ? -16.920 16.196 24.489 1.00 32.70 ? 382 LEU A CD1 1 ATOM 2631 C CD2 . LEU A 1 329 ? -19.343 15.606 24.492 1.00 29.74 ? 382 LEU A CD2 1 ATOM 2632 N N . SER A 1 330 ? -19.248 16.825 29.076 1.00 30.88 ? 383 SER A N 1 ATOM 2633 C CA . SER A 1 330 ? -19.269 16.851 30.533 1.00 30.13 ? 383 SER A CA 1 ATOM 2634 C C . SER A 1 330 ? -18.255 17.837 31.093 1.00 30.78 ? 383 SER A C 1 ATOM 2635 O O . SER A 1 330 ? -17.476 18.429 30.355 1.00 27.88 ? 383 SER A O 1 ATOM 2636 C CB . SER A 1 330 ? -18.939 15.461 31.066 1.00 28.29 ? 383 SER A CB 1 ATOM 2637 O OG . SER A 1 330 ? -17.627 15.095 30.679 1.00 25.14 ? 383 SER A OG 1 ATOM 2638 N N . ARG A 1 331 ? -18.250 17.977 32.415 1.00 35.10 ? 384 ARG A N 1 ATOM 2639 C CA . ARG A 1 331 ? -17.558 19.076 33.075 1.00 37.00 ? 384 ARG A CA 1 ATOM 2640 C C . ARG A 1 331 ? -16.052 18.953 32.866 1.00 35.80 ? 384 ARG A C 1 ATOM 2641 O O . ARG A 1 331 ? -15.355 19.952 32.710 1.00 36.66 ? 384 ARG A O 1 ATOM 2642 C CB . ARG A 1 331 ? -17.894 19.082 34.566 1.00 39.19 ? 384 ARG A CB 1 ATOM 2643 C CG . ARG A 1 331 ? -17.202 20.167 35.373 1.00 41.81 ? 384 ARG A CG 1 ATOM 2644 C CD . ARG A 1 331 ? -17.252 21.559 34.743 1.00 44.73 ? 384 ARG A CD 1 ATOM 2645 N NE . ARG A 1 331 ? -18.598 22.134 34.709 1.00 47.43 ? 384 ARG A NE 1 ATOM 2646 C CZ . ARG A 1 331 ? -18.922 23.228 34.026 1.00 48.36 ? 384 ARG A CZ 1 ATOM 2647 N NH1 . ARG A 1 331 ? -17.999 23.873 33.327 1.00 49.34 ? 384 ARG A NH1 1 ATOM 2648 N NH2 . ARG A 1 331 ? -20.165 23.684 34.042 1.00 49.27 ? 384 ARG A NH2 1 ATOM 2649 N N . THR A 1 332 ? -15.559 17.718 32.851 1.00 33.98 ? 385 THR A N 1 ATOM 2650 C CA . THR A 1 332 ? -14.146 17.455 32.623 1.00 30.90 ? 385 THR A CA 1 ATOM 2651 C C . THR A 1 332 ? -13.712 17.888 31.223 1.00 30.42 ? 385 THR A C 1 ATOM 2652 O O . THR A 1 332 ? -12.585 18.335 31.011 1.00 29.62 ? 385 THR A O 1 ATOM 2653 C CB . THR A 1 332 ? -13.870 15.962 32.784 1.00 30.90 ? 385 THR A CB 1 ATOM 2654 O OG1 . THR A 1 332 ? -13.940 15.592 34.168 1.00 30.92 ? 385 THR A OG1 1 ATOM 2655 C CG2 . THR A 1 332 ? -12.440 15.643 32.392 1.00 32.91 ? 385 THR A CG2 1 ATOM 2656 N N . TYR A 1 333 ? -14.599 17.727 30.255 1.00 30.26 ? 386 TYR A N 1 ATOM 2657 C CA . TYR A 1 333 ? -14.326 18.228 28.924 1.00 31.07 ? 386 TYR A CA 1 ATOM 2658 C C . TYR A 1 333 ? -14.448 19.742 28.914 1.00 31.81 ? 386 TYR A C 1 ATOM 2659 O O . TYR A 1 333 ? -13.593 20.435 28.360 1.00 30.32 ? 386 TYR A O 1 ATOM 2660 C CB . TYR A 1 333 ? -15.251 17.572 27.901 1.00 30.78 ? 386 TYR A CB 1 ATOM 2661 C CG . TYR A 1 333 ? -14.764 16.195 27.522 1.00 29.27 ? 386 TYR A CG 1 ATOM 2662 C CD1 . TYR A 1 333 ? -13.783 16.035 26.571 1.00 28.02 ? 386 TYR A CD1 1 ATOM 2663 C CD2 . TYR A 1 333 ? -15.254 15.061 28.156 1.00 30.88 ? 386 TYR A CD2 1 ATOM 2664 C CE1 . TYR A 1 333 ? -13.317 14.795 26.234 1.00 28.93 ? 386 TYR A CE1 1 ATOM 2665 C CE2 . TYR A 1 333 ? -14.789 13.804 27.828 1.00 29.59 ? 386 TYR A CE2 1 ATOM 2666 C CZ . TYR A 1 333 ? -13.820 13.680 26.864 1.00 28.67 ? 386 TYR A CZ 1 ATOM 2667 O OH . TYR A 1 333 ? -13.335 12.449 26.520 1.00 28.36 ? 386 TYR A OH 1 ATOM 2668 N N . LYS A 1 334 ? -15.487 20.254 29.565 1.00 32.34 ? 387 LYS A N 1 ATOM 2669 C CA . LYS A 1 334 ? -15.634 21.695 29.731 1.00 32.46 ? 387 LYS A CA 1 ATOM 2670 C C . LYS A 1 334 ? -14.332 22.282 30.261 1.00 31.55 ? 387 LYS A C 1 ATOM 2671 O O . LYS A 1 334 ? -13.857 23.290 29.744 1.00 31.45 ? 387 LYS A O 1 ATOM 2672 C CB . LYS A 1 334 ? -16.785 22.020 30.683 1.00 33.36 ? 387 LYS A CB 1 ATOM 2673 C CG . LYS A 1 334 ? -18.173 21.834 30.089 1.00 32.90 ? 387 LYS A CG 1 ATOM 2674 C CD . LYS A 1 334 ? -19.094 22.974 30.506 1.00 33.79 ? 387 LYS A CD 1 ATOM 2675 C CE . LYS A 1 334 ? -20.513 22.506 30.773 1.00 33.05 ? 387 LYS A CE 1 ATOM 2676 N NZ . LYS A 1 334 ? -21.093 21.703 29.657 1.00 34.14 ? 387 LYS A NZ 1 ATOM 2677 N N . GLU A 1 335 ? -13.757 21.635 31.277 1.00 29.25 ? 388 GLU A N 1 ATOM 2678 C CA . GLU A 1 335 ? -12.658 22.204 32.062 1.00 28.45 ? 388 GLU A CA 1 ATOM 2679 C C . GLU A 1 335 ? -11.390 22.393 31.245 1.00 25.79 ? 388 GLU A C 1 ATOM 2680 O O . GLU A 1 335 ? -10.581 23.266 31.547 1.00 24.49 ? 388 GLU A O 1 ATOM 2681 C CB . GLU A 1 335 ? -12.304 21.300 33.248 1.00 32.29 ? 388 GLU A CB 1 ATOM 2682 C CG . GLU A 1 335 ? -13.219 21.411 34.458 1.00 35.84 ? 388 GLU A CG 1 ATOM 2683 C CD . GLU A 1 335 ? -13.069 20.234 35.415 1.00 38.31 ? 388 GLU A CD 1 ATOM 2684 O OE1 . GLU A 1 335 ? -12.027 19.538 35.361 1.00 39.97 ? 388 GLU A OE1 1 ATOM 2685 O OE2 . GLU A 1 335 ? -13.994 20.000 36.223 1.00 42.05 ? 388 GLU A OE2 1 ATOM 2686 N N . SER A 1 336 ? -11.190 21.550 30.237 1.00 24.10 ? 389 SER A N 1 ATOM 2687 C CA . SER A 1 336 ? -9.927 21.548 29.502 1.00 21.88 ? 389 SER A CA 1 ATOM 2688 C C . SER A 1 336 ? -9.794 22.794 28.661 1.00 21.95 ? 389 SER A C 1 ATOM 2689 O O . SER A 1 336 ? -8.724 23.070 28.129 1.00 23.30 ? 389 SER A O 1 ATOM 2690 C CB . SER A 1 336 ? -9.809 20.329 28.589 1.00 21.05 ? 389 SER A CB 1 ATOM 2691 O OG . SER A 1 336 ? -10.814 20.332 27.596 1.00 16.59 ? 389 SER A OG 1 ATOM 2692 N N . ARG A 1 337 ? -10.889 23.535 28.524 1.00 23.49 ? 390 ARG A N 1 ATOM 2693 C CA . ARG A 1 337 ? -10.881 24.755 27.725 1.00 25.50 ? 390 ARG A CA 1 ATOM 2694 C C . ARG A 1 337 ? -10.394 25.932 28.550 1.00 23.19 ? 390 ARG A C 1 ATOM 2695 O O . ARG A 1 337 ? -10.162 27.014 28.019 1.00 23.82 ? 390 ARG A O 1 ATOM 2696 C CB . ARG A 1 337 ? -12.276 25.058 27.170 1.00 26.97 ? 390 ARG A CB 1 ATOM 2697 C CG . ARG A 1 337 ? -12.264 25.613 25.763 1.00 28.21 ? 390 ARG A CG 1 ATOM 2698 C CD . ARG A 1 337 ? -13.632 26.019 25.236 1.00 30.47 ? 390 ARG A CD 1 ATOM 2699 N NE . ARG A 1 337 ? -13.524 26.922 24.091 1.00 33.29 ? 390 ARG A NE 1 ATOM 2700 C CZ . ARG A 1 337 ? -13.900 28.196 24.117 1.00 36.47 ? 390 ARG A CZ 1 ATOM 2701 N NH1 . ARG A 1 337 ? -14.418 28.709 25.226 1.00 36.48 ? 390 ARG A NH1 1 ATOM 2702 N NH2 . ARG A 1 337 ? -13.765 28.958 23.035 1.00 36.40 ? 390 ARG A NH2 1 ATOM 2703 N N . ASN A 1 338 ? -10.264 25.726 29.856 1.00 23.30 ? 391 ASN A N 1 ATOM 2704 C CA . ASN A 1 338 ? -10.256 26.837 30.806 1.00 22.74 ? 391 ASN A CA 1 ATOM 2705 C C . ASN A 1 338 ? -9.234 27.893 30.430 1.00 17.80 ? 391 ASN A C 1 ATOM 2706 O O . ASN A 1 338 ? -9.558 29.059 30.276 1.00 17.77 ? 391 ASN A O 1 ATOM 2707 C CB . ASN A 1 338 ? -9.965 26.328 32.211 1.00 26.47 ? 391 ASN A CB 1 ATOM 2708 C CG . ASN A 1 338 ? -11.197 25.743 32.884 1.00 31.48 ? 391 ASN A CG 1 ATOM 2709 O OD1 . ASN A 1 338 ? -12.327 26.136 32.580 1.00 31.54 ? 391 ASN A OD1 1 ATOM 2710 N ND2 . ASN A 1 338 ? -10.983 24.800 33.807 1.00 32.28 ? 391 ASN A ND2 1 ATOM 2711 N N . ALA A 1 339 ? -7.990 27.471 30.278 1.00 19.08 ? 392 ALA A N 1 ATOM 2712 C CA . ALA A 1 339 ? -6.878 28.392 30.143 1.00 21.31 ? 392 ALA A CA 1 ATOM 2713 C C . ALA A 1 339 ? -6.829 29.026 28.754 1.00 20.80 ? 392 ALA A C 1 ATOM 2714 O O . ALA A 1 339 ? -6.351 30.138 28.599 1.00 23.78 ? 392 ALA A O 1 ATOM 2715 C CB . ALA A 1 339 ? -5.580 27.663 30.436 1.00 23.38 ? 392 ALA A CB 1 ATOM 2716 N N . PHE A 1 340 ? -7.320 28.304 27.752 1.00 22.12 ? 393 PHE A N 1 ATOM 2717 C CA . PHE A 1 340 ? -7.377 28.798 26.379 1.00 22.85 ? 393 PHE A CA 1 ATOM 2718 C C . PHE A 1 340 ? -8.360 29.966 26.234 1.00 24.98 ? 393 PHE A C 1 ATOM 2719 O O . PHE A 1 340 ? -8.040 30.984 25.611 1.00 22.44 ? 393 PHE A O 1 ATOM 2720 C CB . PHE A 1 340 ? -7.782 27.664 25.458 1.00 21.62 ? 393 PHE A CB 1 ATOM 2721 C CG . PHE A 1 340 ? -7.881 28.043 24.002 1.00 23.11 ? 393 PHE A CG 1 ATOM 2722 C CD1 . PHE A 1 340 ? -9.100 28.007 23.349 1.00 23.04 ? 393 PHE A CD1 1 ATOM 2723 C CD2 . PHE A 1 340 ? -6.757 28.369 23.275 1.00 21.96 ? 393 PHE A CD2 1 ATOM 2724 C CE1 . PHE A 1 340 ? -9.197 28.329 22.005 1.00 21.69 ? 393 PHE A CE1 1 ATOM 2725 C CE2 . PHE A 1 340 ? -6.854 28.678 21.935 1.00 22.59 ? 393 PHE A CE2 1 ATOM 2726 C CZ . PHE A 1 340 ? -8.076 28.657 21.301 1.00 20.49 ? 393 PHE A CZ 1 ATOM 2727 N N . ARG A 1 341 ? -9.555 29.838 26.801 1.00 23.56 ? 394 ARG A N 1 ATOM 2728 C CA . ARG A 1 341 ? -10.496 30.939 26.683 1.00 25.97 ? 394 ARG A CA 1 ATOM 2729 C C . ARG A 1 341 ? -10.069 32.130 27.545 1.00 23.86 ? 394 ARG A C 1 ATOM 2730 O O . ARG A 1 341 ? -10.299 33.273 27.167 1.00 16.00 ? 394 ARG A O 1 ATOM 2731 C CB . ARG A 1 341 ? -11.942 30.507 26.978 1.00 27.71 ? 394 ARG A CB 1 ATOM 2732 C CG . ARG A 1 341 ? -12.252 30.253 28.415 1.00 27.93 ? 394 ARG A CG 1 ATOM 2733 C CD . ARG A 1 341 ? -13.516 30.929 28.935 1.00 27.43 ? 394 ARG A CD 1 ATOM 2734 N NE . ARG A 1 341 ? -13.388 31.131 30.374 1.00 30.05 ? 394 ARG A NE 1 ATOM 2735 C CZ . ARG A 1 341 ? -13.388 30.142 31.262 1.00 30.79 ? 394 ARG A CZ 1 ATOM 2736 N NH1 . ARG A 1 341 ? -13.558 28.900 30.863 1.00 29.35 ? 394 ARG A NH1 1 ATOM 2737 N NH2 . ARG A 1 341 ? -13.247 30.392 32.553 1.00 33.49 ? 394 ARG A NH2 1 ATOM 2738 N N . LYS A 1 342 ? -9.415 31.870 28.677 1.00 26.44 ? 395 LYS A N 1 ATOM 2739 C CA . LYS A 1 342 ? -8.792 32.950 29.445 1.00 25.32 ? 395 LYS A CA 1 ATOM 2740 C C . LYS A 1 342 ? -7.772 33.706 28.616 1.00 24.13 ? 395 LYS A C 1 ATOM 2741 O O . LYS A 1 342 ? -7.745 34.938 28.613 1.00 26.27 ? 395 LYS A O 1 ATOM 2742 C CB . LYS A 1 342 ? -8.124 32.424 30.710 1.00 28.38 ? 395 LYS A CB 1 ATOM 2743 C CG . LYS A 1 342 ? -7.377 33.504 31.487 1.00 31.42 ? 395 LYS A CG 1 ATOM 2744 C CD . LYS A 1 342 ? -7.331 33.193 32.970 1.00 34.33 ? 395 LYS A CD 1 ATOM 2745 C CE . LYS A 1 342 ? -6.334 34.066 33.697 1.00 36.31 ? 395 LYS A CE 1 ATOM 2746 N NZ . LYS A 1 342 ? -6.931 35.373 34.099 1.00 38.05 ? 395 LYS A NZ 1 ATOM 2747 N N . ALA A 1 343 ? -6.926 32.975 27.907 1.00 22.29 ? 396 ALA A N 1 ATOM 2748 C CA . ALA A 1 343 ? -5.936 33.606 27.046 1.00 18.97 ? 396 ALA A CA 1 ATOM 2749 C C . ALA A 1 343 ? -6.549 34.464 25.919 1.00 17.70 ? 396 ALA A C 1 ATOM 2750 O O . ALA A 1 343 ? -6.002 35.517 25.568 1.00 15.36 ? 396 ALA A O 1 ATOM 2751 C CB . ALA A 1 343 ? -4.998 32.549 26.459 1.00 21.23 ? 396 ALA A CB 1 ATOM 2752 N N . LEU A 1 344 ? -7.654 34.020 25.330 1.00 16.83 ? 397 LEU A N 1 ATOM 2753 C CA . LEU A 1 344 ? -8.238 34.764 24.221 1.00 17.81 ? 397 LEU A CA 1 ATOM 2754 C C . LEU A 1 344 ? -9.164 35.867 24.718 1.00 19.75 ? 397 LEU A C 1 ATOM 2755 O O . LEU A 1 344 ? -9.339 36.895 24.048 1.00 19.73 ? 397 LEU A O 1 ATOM 2756 C CB . LEU A 1 344 ? -9.007 33.851 23.267 1.00 21.84 ? 397 LEU A CB 1 ATOM 2757 C CG . LEU A 1 344 ? -8.364 32.574 22.748 1.00 25.33 ? 397 LEU A CG 1 ATOM 2758 C CD1 . LEU A 1 344 ? -9.238 32.011 21.645 1.00 25.54 ? 397 LEU A CD1 1 ATOM 2759 C CD2 . LEU A 1 344 ? -6.941 32.787 22.268 1.00 24.45 ? 397 LEU A CD2 1 ATOM 2760 N N . TYR A 1 345 ? -9.761 35.652 25.888 1.00 21.00 ? 398 TYR A N 1 ATOM 2761 C CA . TYR A 1 345 ? -10.933 36.408 26.299 1.00 19.48 ? 398 TYR A CA 1 ATOM 2762 C C . TYR A 1 345 ? -10.769 37.059 27.669 1.00 21.99 ? 398 TYR A C 1 ATOM 2763 O O . TYR A 1 345 ? -11.451 38.036 27.977 1.00 23.65 ? 398 TYR A O 1 ATOM 2764 C CB . TYR A 1 345 ? -12.144 35.494 26.318 1.00 19.52 ? 398 TYR A CB 1 ATOM 2765 C CG . TYR A 1 345 ? -12.500 34.973 24.951 1.00 21.35 ? 398 TYR A CG 1 ATOM 2766 C CD1 . TYR A 1 345 ? -12.962 35.837 23.968 1.00 20.04 ? 398 TYR A CD1 1 ATOM 2767 C CD2 . TYR A 1 345 ? -12.365 33.618 24.634 1.00 19.86 ? 398 TYR A CD2 1 ATOM 2768 C CE1 . TYR A 1 345 ? -13.283 35.379 22.719 1.00 22.59 ? 398 TYR A CE1 1 ATOM 2769 C CE2 . TYR A 1 345 ? -12.689 33.150 23.373 1.00 19.47 ? 398 TYR A CE2 1 ATOM 2770 C CZ . TYR A 1 345 ? -13.139 34.035 22.422 1.00 20.75 ? 398 TYR A CZ 1 ATOM 2771 O OH . TYR A 1 345 ? -13.468 33.607 21.166 1.00 20.88 ? 398 TYR A OH 1 ATOM 2772 N N . GLY A 1 346 ? -9.888 36.508 28.499 1.00 21.15 ? 399 GLY A N 1 ATOM 2773 C CA . GLY A 1 346 ? -9.627 37.079 29.811 1.00 20.68 ? 399 GLY A CA 1 ATOM 2774 C C . GLY A 1 346 ? -10.667 36.734 30.863 1.00 22.82 ? 399 GLY A C 1 ATOM 2775 O O . GLY A 1 346 ? -10.583 37.208 31.993 1.00 23.65 ? 399 GLY A O 1 ATOM 2776 N N . THR A 1 347 ? -11.635 35.894 30.496 1.00 22.42 ? 400 THR A N 1 ATOM 2777 C CA . THR A 1 347 ? -12.676 35.463 31.414 1.00 22.07 ? 400 THR A CA 1 ATOM 2778 C C . THR A 1 347 ? -12.200 34.290 32.271 1.00 22.04 ? 400 THR A C 1 ATOM 2779 O O . THR A 1 347 ? -11.396 33.476 31.827 1.00 21.46 ? 400 THR A O 1 ATOM 2780 C CB . THR A 1 347 ? -13.928 35.031 30.629 1.00 22.94 ? 400 THR A CB 1 ATOM 2781 O OG1 . THR A 1 347 ? -13.593 33.988 29.701 1.00 20.73 ? 400 THR A OG1 1 ATOM 2782 C CG2 . THR A 1 347 ? -14.435 36.150 29.748 1.00 22.87 ? 400 THR A CG2 1 ATOM 2783 N N . THR A 1 348 ? -12.701 34.203 33.497 1.00 19.35 ? 401 THR A N 1 ATOM 2784 C CA . THR A 1 348 ? -12.232 33.186 34.427 1.00 20.52 ? 401 THR A CA 1 ATOM 2785 C C . THR A 1 348 ? -13.281 32.117 34.648 1.00 20.10 ? 401 THR A C 1 ATOM 2786 O O . THR A 1 348 ? -13.037 31.151 35.357 1.00 22.68 ? 401 THR A O 1 ATOM 2787 C CB . THR A 1 348 ? -11.820 33.806 35.785 1.00 20.00 ? 401 THR A CB 1 ATOM 2788 O OG1 . THR A 1 348 ? -12.899 34.552 36.355 1.00 19.46 ? 401 THR A OG1 1 ATOM 2789 C CG2 . THR A 1 348 ? -10.756 34.832 35.595 1.00 22.19 ? 401 THR A CG2 1 ATOM 2790 N N . SER A 1 349 ? -14.443 32.286 34.035 1.00 19.64 ? 402 SER A N 1 ATOM 2791 C CA . SER A 1 349 ? -15.502 31.296 34.145 1.00 22.66 ? 402 SER A CA 1 ATOM 2792 C C . SER A 1 349 ? -16.439 31.352 32.932 1.00 24.09 ? 402 SER A C 1 ATOM 2793 O O . SER A 1 349 ? -16.532 32.371 32.258 1.00 22.95 ? 402 SER A O 1 ATOM 2794 C CB . SER A 1 349 ? -16.280 31.524 35.450 1.00 25.08 ? 402 SER A CB 1 ATOM 2795 O OG . SER A 1 349 ? -17.557 30.923 35.403 1.00 28.67 ? 402 SER A OG 1 ATOM 2796 N N . GLU A 1 350 ? -17.122 30.244 32.662 1.00 26.66 ? 403 GLU A N 1 ATOM 2797 C CA . GLU A 1 350 ? -18.269 30.217 31.760 1.00 28.38 ? 403 GLU A CA 1 ATOM 2798 C C . GLU A 1 350 ? -19.372 31.149 32.237 1.00 25.35 ? 403 GLU A C 1 ATOM 2799 O O . GLU A 1 350 ? -19.640 31.203 33.434 1.00 21.34 ? 403 GLU A O 1 ATOM 2800 C CB . GLU A 1 350 ? -18.844 28.804 31.694 1.00 31.80 ? 403 GLU A CB 1 ATOM 2801 C CG . GLU A 1 350 ? -18.361 27.961 30.533 1.00 35.51 ? 403 GLU A CG 1 ATOM 2802 C CD . GLU A 1 350 ? -18.682 26.491 30.744 1.00 40.63 ? 403 GLU A CD 1 ATOM 2803 O OE1 . GLU A 1 350 ? -19.012 26.124 31.903 1.00 43.19 ? 403 GLU A OE1 1 ATOM 2804 O OE2 . GLU A 1 350 ? -18.612 25.709 29.761 1.00 40.36 ? 403 GLU A OE2 1 ATOM 2805 N N . THR A 1 351 ? -20.011 31.852 31.291 1.00 22.44 ? 404 THR A N 1 ATOM 2806 C CA . THR A 1 351 ? -21.326 32.473 31.497 1.00 23.55 ? 404 THR A CA 1 ATOM 2807 C C . THR A 1 351 ? -22.354 31.470 31.998 1.00 19.06 ? 404 THR A C 1 ATOM 2808 O O . THR A 1 351 ? -22.190 30.271 31.820 1.00 18.67 ? 404 THR A O 1 ATOM 2809 C CB . THR A 1 351 ? -21.859 33.116 30.181 1.00 25.53 ? 404 THR A CB 1 ATOM 2810 O OG1 . THR A 1 351 ? -22.941 34.013 30.465 1.00 26.26 ? 404 THR A OG1 1 ATOM 2811 C CG2 . THR A 1 351 ? -22.540 32.085 29.309 1.00 27.57 ? 404 THR A CG2 1 ATOM 2812 N N . ALA A 1 352 ? -23.406 31.967 32.639 1.00 17.39 ? 405 ALA A N 1 ATOM 2813 C CA . ALA A 1 352 ? -24.431 31.097 33.191 1.00 18.55 ? 405 ALA A CA 1 ATOM 2814 C C . ALA A 1 352 ? -24.975 30.173 32.108 1.00 19.55 ? 405 ALA A C 1 ATOM 2815 O O . ALA A 1 352 ? -25.141 30.567 30.951 1.00 22.87 ? 405 ALA A O 1 ATOM 2816 C CB . ALA A 1 352 ? -25.542 31.911 33.793 1.00 19.32 ? 405 ALA A CB 1 ATOM 2817 N N . THR A 1 353 ? -25.249 28.939 32.495 1.00 19.50 ? 406 THR A N 1 ATOM 2818 C CA . THR A 1 353 ? -25.694 27.920 31.561 1.00 20.33 ? 406 THR A CA 1 ATOM 2819 C C . THR A 1 353 ? -27.021 28.300 30.903 1.00 19.63 ? 406 THR A C 1 ATOM 2820 O O . THR A 1 353 ? -27.210 28.088 29.705 1.00 22.47 ? 406 THR A O 1 ATOM 2821 C CB . THR A 1 353 ? -25.812 26.579 32.272 1.00 21.51 ? 406 THR A CB 1 ATOM 2822 O OG1 . THR A 1 353 ? -24.501 26.113 32.623 1.00 23.07 ? 406 THR A OG1 1 ATOM 2823 C CG2 . THR A 1 353 ? -26.348 25.507 31.305 1.00 23.33 ? 406 THR A CG2 1 ATOM 2824 N N . TRP A 1 354 ? -27.918 28.895 31.672 1.00 16.65 ? 407 TRP A N 1 ATOM 2825 C CA . TRP A 1 354 ? -29.191 29.341 31.126 1.00 19.00 ? 407 TRP A CA 1 ATOM 2826 C C . TRP A 1 354 ? -29.015 30.425 30.054 1.00 19.12 ? 407 TRP A C 1 ATOM 2827 O O . TRP A 1 354 ? -29.744 30.438 29.059 1.00 16.61 ? 407 TRP A O 1 ATOM 2828 C CB . TRP A 1 354 ? -30.170 29.765 32.246 1.00 18.29 ? 407 TRP A CB 1 ATOM 2829 C CG . TRP A 1 354 ? -29.935 31.120 32.915 1.00 20.06 ? 407 TRP A CG 1 ATOM 2830 C CD1 . TRP A 1 354 ? -29.408 31.340 34.172 1.00 20.05 ? 407 TRP A CD1 1 ATOM 2831 C CD2 . TRP A 1 354 ? -30.270 32.418 32.399 1.00 18.61 ? 407 TRP A CD2 1 ATOM 2832 N NE1 . TRP A 1 354 ? -29.378 32.686 34.445 1.00 20.10 ? 407 TRP A NE1 1 ATOM 2833 C CE2 . TRP A 1 354 ? -29.895 33.372 33.375 1.00 19.77 ? 407 TRP A CE2 1 ATOM 2834 C CE3 . TRP A 1 354 ? -30.829 32.876 31.203 1.00 19.14 ? 407 TRP A CE3 1 ATOM 2835 C CZ2 . TRP A 1 354 ? -30.068 34.738 33.193 1.00 18.73 ? 407 TRP A CZ2 1 ATOM 2836 C CZ3 . TRP A 1 354 ? -30.999 34.247 31.021 1.00 19.59 ? 407 TRP A CZ3 1 ATOM 2837 C CH2 . TRP A 1 354 ? -30.623 35.157 32.015 1.00 19.60 ? 407 TRP A CH2 1 ATOM 2838 N N . ARG A 1 355 ? -28.034 31.304 30.233 1.00 17.73 ? 408 ARG A N 1 ATOM 2839 C CA . ARG A 1 355 ? -27.766 32.349 29.242 1.00 16.85 ? 408 ARG A CA 1 ATOM 2840 C C . ARG A 1 355 ? -27.156 31.774 27.966 1.00 18.79 ? 408 ARG A C 1 ATOM 2841 O O . ARG A 1 355 ? -27.557 32.155 26.860 1.00 14.90 ? 408 ARG A O 1 ATOM 2842 C CB . ARG A 1 355 ? -26.815 33.408 29.796 1.00 15.18 ? 408 ARG A CB 1 ATOM 2843 C CG . ARG A 1 355 ? -27.379 34.244 30.930 1.00 16.63 ? 408 ARG A CG 1 ATOM 2844 C CD . ARG A 1 355 ? -26.401 35.292 31.447 1.00 15.76 ? 408 ARG A CD 1 ATOM 2845 N NE . ARG A 1 355 ? -26.936 36.029 32.578 1.00 16.05 ? 408 ARG A NE 1 ATOM 2846 C CZ . ARG A 1 355 ? -27.725 37.083 32.469 1.00 16.72 ? 408 ARG A CZ 1 ATOM 2847 N NH1 . ARG A 1 355 ? -28.064 37.542 31.265 1.00 17.50 ? 408 ARG A NH1 1 ATOM 2848 N NH2 . ARG A 1 355 ? -28.163 37.697 33.559 1.00 15.11 ? 408 ARG A NH2 1 ATOM 2849 N N . ARG A 1 356 ? -26.174 30.885 28.128 1.00 18.09 ? 409 ARG A N 1 ATOM 2850 C CA . ARG A 1 356 ? -25.508 30.251 26.991 1.00 20.51 ? 409 ARG A CA 1 ATOM 2851 C C . ARG A 1 356 ? -26.570 29.551 26.185 1.00 20.53 ? 409 ARG A C 1 ATOM 2852 O O . ARG A 1 356 ? -26.568 29.581 24.947 1.00 21.52 ? 409 ARG A O 1 ATOM 2853 C CB . ARG A 1 356 ? -24.491 29.209 27.454 1.00 23.25 ? 409 ARG A CB 1 ATOM 2854 C CG . ARG A 1 356 ? -23.085 29.742 27.601 1.00 27.90 ? 409 ARG A CG 1 ATOM 2855 C CD . ARG A 1 356 ? -22.140 28.869 28.421 1.00 30.18 ? 409 ARG A CD 1 ATOM 2856 N NE . ARG A 1 356 ? -22.555 27.475 28.537 1.00 32.34 ? 409 ARG A NE 1 ATOM 2857 C CZ . ARG A 1 356 ? -22.574 26.814 29.688 1.00 34.75 ? 409 ARG A CZ 1 ATOM 2858 N NH1 . ARG A 1 356 ? -22.218 27.438 30.802 1.00 35.31 ? 409 ARG A NH1 1 ATOM 2859 N NH2 . ARG A 1 356 ? -22.946 25.540 29.740 1.00 35.24 ? 409 ARG A NH2 1 ATOM 2860 N N . CYS A 1 357 ? -27.479 28.923 26.918 1.00 17.47 ? 410 CYS A N 1 ATOM 2861 C CA . CYS A 1 357 ? -28.489 28.075 26.331 1.00 20.35 ? 410 CYS A CA 1 ATOM 2862 C C . CYS A 1 357 ? -29.578 28.915 25.686 1.00 16.79 ? 410 CYS A C 1 ATOM 2863 O O . CYS A 1 357 ? -30.005 28.630 24.570 1.00 18.00 ? 410 CYS A O 1 ATOM 2864 C CB . CYS A 1 357 ? -29.048 27.128 27.392 1.00 19.95 ? 410 CYS A CB 1 ATOM 2865 S SG . CYS A 1 357 ? -27.872 25.805 27.783 1.00 19.72 ? 410 CYS A SG 1 ATOM 2866 N N . ALA A 1 358 ? -29.981 29.979 26.365 1.00 15.30 ? 411 ALA A N 1 ATOM 2867 C CA . ALA A 1 358 ? -30.912 30.930 25.797 1.00 13.91 ? 411 ALA A CA 1 ATOM 2868 C C . ALA A 1 358 ? -30.405 31.451 24.470 1.00 16.73 ? 411 ALA A C 1 ATOM 2869 O O . ALA A 1 358 ? -31.188 31.581 23.523 1.00 14.35 ? 411 ALA A O 1 ATOM 2870 C CB . ALA A 1 358 ? -31.138 32.058 26.739 1.00 15.68 ? 411 ALA A CB 1 ATOM 2871 N N . ASN A 1 359 ? -29.101 31.727 24.396 1.00 18.09 ? 412 ASN A N 1 ATOM 2872 C CA . ASN A 1 359 ? -28.499 32.342 23.211 1.00 20.42 ? 412 ASN A CA 1 ATOM 2873 C C . ASN A 1 359 ? -28.356 31.305 22.112 1.00 18.81 ? 412 ASN A C 1 ATOM 2874 O O . ASN A 1 359 ? -28.569 31.594 20.953 1.00 18.55 ? 412 ASN A O 1 ATOM 2875 C CB . ASN A 1 359 ? -27.141 32.975 23.553 1.00 25.65 ? 412 ASN A CB 1 ATOM 2876 C CG . ASN A 1 359 ? -26.405 33.560 22.318 1.00 31.37 ? 412 ASN A CG 1 ATOM 2877 O OD1 . ASN A 1 359 ? -27.010 34.164 21.420 1.00 37.15 ? 412 ASN A OD1 1 ATOM 2878 N ND2 . ASN A 1 359 ? -25.085 33.399 22.297 1.00 34.73 ? 412 ASN A ND2 1 ATOM 2879 N N . TYR A 1 360 ? -28.022 30.079 22.483 1.00 20.36 ? 413 TYR A N 1 ATOM 2880 C CA . TYR A 1 360 ? -27.865 29.015 21.499 1.00 20.24 ? 413 TYR A CA 1 ATOM 2881 C C . TYR A 1 360 ? -29.180 28.716 20.765 1.00 21.57 ? 413 TYR A C 1 ATOM 2882 O O . TYR A 1 360 ? -29.231 28.694 19.538 1.00 24.71 ? 413 TYR A O 1 ATOM 2883 C CB . TYR A 1 360 ? -27.325 27.750 22.168 1.00 21.55 ? 413 TYR A CB 1 ATOM 2884 C CG . TYR A 1 360 ? -27.245 26.578 21.231 1.00 20.70 ? 413 TYR A CG 1 ATOM 2885 C CD1 . TYR A 1 360 ? -28.290 25.672 21.134 1.00 18.14 ? 413 TYR A CD1 1 ATOM 2886 C CD2 . TYR A 1 360 ? -26.135 26.393 20.419 1.00 19.93 ? 413 TYR A CD2 1 ATOM 2887 C CE1 . TYR A 1 360 ? -28.234 24.616 20.259 1.00 18.54 ? 413 TYR A CE1 1 ATOM 2888 C CE2 . TYR A 1 360 ? -26.062 25.329 19.540 1.00 18.87 ? 413 TYR A CE2 1 ATOM 2889 C CZ . TYR A 1 360 ? -27.114 24.445 19.460 1.00 20.33 ? 413 TYR A CZ 1 ATOM 2890 O OH . TYR A 1 360 ? -27.041 23.383 18.581 1.00 22.47 ? 413 TYR A OH 1 ATOM 2891 N N . VAL A 1 361 ? -30.252 28.510 21.516 1.00 23.88 ? 414 VAL A N 1 ATOM 2892 C CA . VAL A 1 361 ? -31.574 28.355 20.922 1.00 20.96 ? 414 VAL A CA 1 ATOM 2893 C C . VAL A 1 361 ? -31.976 29.536 20.030 1.00 19.32 ? 414 VAL A C 1 ATOM 2894 O O . VAL A 1 361 ? -32.445 29.337 18.917 1.00 16.26 ? 414 VAL A O 1 ATOM 2895 C CB . VAL A 1 361 ? -32.613 28.177 22.000 1.00 23.85 ? 414 VAL A CB 1 ATOM 2896 C CG1 . VAL A 1 361 ? -32.382 26.875 22.734 1.00 24.49 ? 414 VAL A CG1 1 ATOM 2897 C CG2 . VAL A 1 361 ? -32.531 29.326 22.973 1.00 29.43 ? 414 VAL A CG2 1 ATOM 2898 N N . ASN A 1 362 ? -31.794 30.760 20.511 1.00 17.04 ? 415 ASN A N 1 ATOM 2899 C CA . ASN A 1 362 ? -31.948 31.936 19.659 1.00 15.93 ? 415 ASN A CA 1 ATOM 2900 C C . ASN A 1 362 ? -31.137 31.799 18.372 1.00 15.74 ? 415 ASN A C 1 ATOM 2901 O O . ASN A 1 362 ? -31.638 32.094 17.286 1.00 15.68 ? 415 ASN A O 1 ATOM 2902 C CB . ASN A 1 362 ? -31.543 33.199 20.411 1.00 16.52 ? 415 ASN A CB 1 ATOM 2903 C CG . ASN A 1 362 ? -32.106 34.470 19.789 1.00 18.03 ? 415 ASN A CG 1 ATOM 2904 O OD1 . ASN A 1 362 ? -33.079 34.432 19.043 1.00 20.34 ? 415 ASN A OD1 1 ATOM 2905 N ND2 . ASN A 1 362 ? -31.490 35.612 20.108 1.00 17.75 ? 415 ASN A ND2 1 ATOM 2906 N N . GLY A 1 363 ? -29.904 31.326 18.494 1.00 14.24 ? 416 GLY A N 1 ATOM 2907 C CA . GLY A 1 363 ? -29.033 31.174 17.343 1.00 15.92 ? 416 GLY A CA 1 ATOM 2908 C C . GLY A 1 363 ? -29.624 30.262 16.287 1.00 18.72 ? 416 GLY A C 1 ATOM 2909 O O . GLY A 1 363 ? -29.488 30.514 15.084 1.00 17.76 ? 416 GLY A O 1 ATOM 2910 N N . ASN A 1 364 ? -30.297 29.205 16.738 1.00 16.21 ? 417 ASN A N 1 ATOM 2911 C CA . ASN A 1 364 ? -30.625 28.095 15.871 1.00 19.99 ? 417 ASN A CA 1 ATOM 2912 C C . ASN A 1 364 ? -32.111 28.120 15.484 1.00 20.85 ? 417 ASN A C 1 ATOM 2913 O O . ASN A 1 364 ? -32.538 27.435 14.558 1.00 24.59 ? 417 ASN A O 1 ATOM 2914 C CB . ASN A 1 364 ? -30.219 26.773 16.535 1.00 18.34 ? 417 ASN A CB 1 ATOM 2915 C CG . ASN A 1 364 ? -28.718 26.502 16.419 1.00 23.07 ? 417 ASN A CG 1 ATOM 2916 O OD1 . ASN A 1 364 ? -28.261 25.861 15.470 1.00 23.86 ? 417 ASN A OD1 1 ATOM 2917 N ND2 . ASN A 1 364 ? -27.941 27.001 17.382 1.00 24.61 ? 417 ASN A ND2 1 ATOM 2918 N N . MET A 1 365 ? -32.886 28.940 16.180 1.00 19.08 ? 418 MET A N 1 ATOM 2919 C CA . MET A 1 365 ? -34.321 29.000 15.967 1.00 16.66 ? 418 MET A CA 1 ATOM 2920 C C . MET A 1 365 ? -34.766 30.433 16.113 1.00 17.29 ? 418 MET A C 1 ATOM 2921 O O . MET A 1 365 ? -35.661 30.733 16.912 1.00 17.02 ? 418 MET A O 1 ATOM 2922 C CB . MET A 1 365 ? -35.085 28.156 16.984 1.00 14.74 ? 418 MET A CB 1 ATOM 2923 C CG . MET A 1 365 ? -34.675 26.714 17.074 1.00 15.87 ? 418 MET A CG 1 ATOM 2924 S SD . MET A 1 365 ? -35.942 25.714 17.896 1.00 17.57 ? 418 MET A SD 1 ATOM 2925 C CE . MET A 1 365 ? -37.306 25.961 16.808 1.00 16.16 ? 418 MET A CE 1 ATOM 2926 N N . GLU A 1 366 ? -34.150 31.305 15.323 1.00 16.44 ? 419 GLU A N 1 ATOM 2927 C CA . GLU A 1 366 ? -34.172 32.726 15.576 1.00 18.45 ? 419 GLU A CA 1 ATOM 2928 C C . GLU A 1 366 ? -35.573 33.299 15.357 1.00 19.75 ? 419 GLU A C 1 ATOM 2929 O O . GLU A 1 366 ? -35.964 34.269 16.009 1.00 23.62 ? 419 GLU A O 1 ATOM 2930 C CB . GLU A 1 366 ? -33.124 33.440 14.708 1.00 20.97 ? 419 GLU A CB 1 ATOM 2931 C CG . GLU A 1 366 ? -33.526 33.636 13.254 1.00 26.24 ? 419 GLU A CG 1 ATOM 2932 C CD . GLU A 1 366 ? -32.332 33.754 12.317 1.00 29.26 ? 419 GLU A CD 1 ATOM 2933 O OE1 . GLU A 1 366 ? -31.245 33.233 12.665 1.00 30.30 ? 419 GLU A OE1 1 ATOM 2934 O OE2 . GLU A 1 366 ? -32.486 34.372 11.228 1.00 31.66 ? 419 GLU A OE2 1 ATOM 2935 N N . ASN A 1 367 ? -36.355 32.701 14.470 1.00 19.96 ? 420 ASN A N 1 ATOM 2936 C CA . ASN A 1 367 ? -37.688 33.242 14.218 1.00 20.81 ? 420 ASN A CA 1 ATOM 2937 C C . ASN A 1 367 ? -38.652 32.821 15.285 1.00 19.80 ? 420 ASN A C 1 ATOM 2938 O O . ASN A 1 367 ? -39.433 33.623 15.764 1.00 25.35 ? 420 ASN A O 1 ATOM 2939 C CB . ASN A 1 367 ? -38.214 32.838 12.843 1.00 21.11 ? 420 ASN A CB 1 ATOM 2940 C CG . ASN A 1 367 ? -37.510 33.557 11.745 1.00 21.40 ? 420 ASN A CG 1 ATOM 2941 O OD1 . ASN A 1 367 ? -36.918 34.611 11.981 1.00 22.25 ? 420 ASN A OD1 1 ATOM 2942 N ND2 . ASN A 1 367 ? -37.532 32.991 10.537 1.00 23.93 ? 420 ASN A ND2 1 ATOM 2943 N N . ALA A 1 368 ? -38.566 31.561 15.679 1.00 20.35 ? 421 ALA A N 1 ATOM 2944 C CA . ALA A 1 368 ? -39.336 31.052 16.795 1.00 19.51 ? 421 ALA A CA 1 ATOM 2945 C C . ALA A 1 368 ? -38.995 31.796 18.097 1.00 19.19 ? 421 ALA A C 1 ATOM 2946 O O . ALA A 1 368 ? -39.842 32.423 18.700 1.00 19.94 ? 421 ALA A O 1 ATOM 2947 C CB . ALA A 1 368 ? -39.092 29.561 16.952 1.00 20.15 ? 421 ALA A CB 1 ATOM 2948 N N . VAL A 1 369 ? -37.754 31.745 18.540 1.00 21.17 ? 422 VAL A N 1 ATOM 2949 C CA . VAL A 1 369 ? -37.370 32.531 19.708 1.00 16.43 ? 422 VAL A CA 1 ATOM 2950 C C . VAL A 1 369 ? -37.824 33.980 19.539 1.00 19.12 ? 422 VAL A C 1 ATOM 2951 O O . VAL A 1 369 ? -38.234 34.631 20.493 1.00 20.14 ? 422 VAL A O 1 ATOM 2952 C CB . VAL A 1 369 ? -35.859 32.499 19.914 1.00 14.30 ? 422 VAL A CB 1 ATOM 2953 C CG1 . VAL A 1 369 ? -35.461 33.402 21.070 1.00 15.94 ? 422 VAL A CG1 1 ATOM 2954 C CG2 . VAL A 1 369 ? -35.412 31.087 20.147 1.00 13.22 ? 422 VAL A CG2 1 ATOM 2955 N N . GLY A 1 370 ? -37.748 34.485 18.313 1.00 21.77 ? 423 GLY A N 1 ATOM 2956 C CA . GLY A 1 370 ? -38.035 35.884 18.051 1.00 18.72 ? 423 GLY A CA 1 ATOM 2957 C C . GLY A 1 370 ? -39.519 36.217 18.202 1.00 19.61 ? 423 GLY A C 1 ATOM 2958 O O . GLY A 1 370 ? -39.876 37.280 18.717 1.00 16.21 ? 423 GLY A O 1 ATOM 2959 N N . ARG A 1 371 ? -40.387 35.312 17.755 1.00 19.26 ? 424 ARG A N 1 ATOM 2960 C CA . ARG A 1 371 ? -41.806 35.445 18.007 1.00 19.97 ? 424 ARG A CA 1 ATOM 2961 C C . ARG A 1 371 ? -42.044 35.663 19.495 1.00 18.10 ? 424 ARG A C 1 ATOM 2962 O O . ARG A 1 371 ? -42.788 36.542 19.887 1.00 11.62 ? 424 ARG A O 1 ATOM 2963 C CB . ARG A 1 371 ? -42.556 34.200 17.516 1.00 25.52 ? 424 ARG A CB 1 ATOM 2964 C CG . ARG A 1 371 ? -44.052 34.125 17.902 1.00 27.92 ? 424 ARG A CG 1 ATOM 2965 C CD . ARG A 1 371 ? -44.476 32.730 18.354 1.00 32.57 ? 424 ARG A CD 1 ATOM 2966 N NE . ARG A 1 371 ? -45.926 32.495 18.374 1.00 33.69 ? 424 ARG A NE 1 ATOM 2967 C CZ . ARG A 1 371 ? -46.657 32.231 17.301 1.00 33.48 ? 424 ARG A CZ 1 ATOM 2968 N NH1 . ARG A 1 371 ? -46.094 32.212 16.102 1.00 30.88 ? 424 ARG A NH1 1 ATOM 2969 N NH2 . ARG A 1 371 ? -47.963 32.009 17.421 1.00 32.59 ? 424 ARG A NH2 1 ATOM 2970 N N . LEU A 1 372 ? -41.403 34.857 20.324 1.00 18.82 ? 425 LEU A N 1 ATOM 2971 C CA . LEU A 1 372 ? -41.704 34.883 21.741 1.00 20.60 ? 425 LEU A CA 1 ATOM 2972 C C . LEU A 1 372 ? -41.239 36.215 22.309 1.00 19.65 ? 425 LEU A C 1 ATOM 2973 O O . LEU A 1 372 ? -41.941 36.833 23.109 1.00 17.39 ? 425 LEU A O 1 ATOM 2974 C CB . LEU A 1 372 ? -41.019 33.710 22.444 1.00 22.21 ? 425 LEU A CB 1 ATOM 2975 C CG . LEU A 1 372 ? -41.640 32.383 22.023 1.00 23.52 ? 425 LEU A CG 1 ATOM 2976 C CD1 . LEU A 1 372 ? -40.720 31.212 22.291 1.00 22.00 ? 425 LEU A CD1 1 ATOM 2977 C CD2 . LEU A 1 372 ? -42.976 32.223 22.742 1.00 24.89 ? 425 LEU A CD2 1 ATOM 2978 N N . TYR A 1 373 ? -40.060 36.659 21.874 1.00 21.61 ? 426 TYR A N 1 ATOM 2979 C CA . TYR A 1 373 ? -39.436 37.853 22.433 1.00 19.74 ? 426 TYR A CA 1 ATOM 2980 C C . TYR A 1 373 ? -40.336 39.033 22.171 1.00 20.30 ? 426 TYR A C 1 ATOM 2981 O O . TYR A 1 373 ? -40.534 39.903 23.030 1.00 17.80 ? 426 TYR A O 1 ATOM 2982 C CB . TYR A 1 373 ? -38.058 38.105 21.807 1.00 20.05 ? 426 TYR A CB 1 ATOM 2983 C CG . TYR A 1 373 ? -37.450 39.425 22.182 1.00 17.36 ? 426 TYR A CG 1 ATOM 2984 C CD1 . TYR A 1 373 ? -36.981 39.649 23.460 1.00 17.84 ? 426 TYR A CD1 1 ATOM 2985 C CD2 . TYR A 1 373 ? -37.367 40.465 21.264 1.00 20.92 ? 426 TYR A CD2 1 ATOM 2986 C CE1 . TYR A 1 373 ? -36.436 40.860 23.816 1.00 19.51 ? 426 TYR A CE1 1 ATOM 2987 C CE2 . TYR A 1 373 ? -36.819 41.681 21.610 1.00 19.32 ? 426 TYR A CE2 1 ATOM 2988 C CZ . TYR A 1 373 ? -36.354 41.872 22.892 1.00 19.60 ? 426 TYR A CZ 1 ATOM 2989 O OH . TYR A 1 373 ? -35.801 43.075 23.265 1.00 22.48 ? 426 TYR A OH 1 ATOM 2990 N N . VAL A 1 374 ? -40.886 39.067 20.970 1.00 22.31 ? 427 VAL A N 1 ATOM 2991 C CA . VAL A 1 374 ? -41.643 40.226 20.551 1.00 24.40 ? 427 VAL A CA 1 ATOM 2992 C C . VAL A 1 374 ? -42.954 40.280 21.343 1.00 25.61 ? 427 VAL A C 1 ATOM 2993 O O . VAL A 1 374 ? -43.357 41.340 21.814 1.00 19.46 ? 427 VAL A O 1 ATOM 2994 C CB . VAL A 1 374 ? -41.905 40.193 19.042 1.00 25.80 ? 427 VAL A CB 1 ATOM 2995 C CG1 . VAL A 1 374 ? -40.624 40.536 18.281 1.00 27.23 ? 427 VAL A CG1 1 ATOM 2996 C CG2 . VAL A 1 374 ? -42.424 38.826 18.626 1.00 27.51 ? 427 VAL A CG2 1 ATOM 2997 N N . GLU A 1 375 ? -43.604 39.131 21.499 1.00 26.49 ? 428 GLU A N 1 ATOM 2998 C CA . GLU A 1 375 ? -44.836 39.055 22.282 1.00 30.94 ? 428 GLU A CA 1 ATOM 2999 C C . GLU A 1 375 ? -44.634 39.564 23.698 1.00 29.72 ? 428 GLU A C 1 ATOM 3000 O O . GLU A 1 375 ? -45.494 40.250 24.248 1.00 31.81 ? 428 GLU A O 1 ATOM 3001 C CB . GLU A 1 375 ? -45.353 37.616 22.351 1.00 33.38 ? 428 GLU A CB 1 ATOM 3002 C CG . GLU A 1 375 ? -45.428 36.920 21.009 1.00 36.81 ? 428 GLU A CG 1 ATOM 3003 C CD . GLU A 1 375 ? -46.245 35.646 21.066 1.00 40.16 ? 428 GLU A CD 1 ATOM 3004 O OE1 . GLU A 1 375 ? -45.807 34.678 21.733 1.00 39.31 ? 428 GLU A OE1 1 ATOM 3005 O OE2 . GLU A 1 375 ? -47.328 35.621 20.441 1.00 44.04 ? 428 GLU A OE2 1 ATOM 3006 N N . ALA A 1 376 ? -43.512 39.202 24.307 1.00 28.49 ? 429 ALA A N 1 ATOM 3007 C CA . ALA A 1 376 ? -43.279 39.587 25.689 1.00 28.47 ? 429 ALA A CA 1 ATOM 3008 C C . ALA A 1 376 ? -42.886 41.062 25.792 1.00 26.55 ? 429 ALA A C 1 ATOM 3009 O O . ALA A 1 376 ? -43.311 41.745 26.713 1.00 29.07 ? 429 ALA A O 1 ATOM 3010 C CB . ALA A 1 376 ? -42.231 38.691 26.331 1.00 27.99 ? 429 ALA A CB 1 ATOM 3011 N N . ALA A 1 377 ? -42.090 41.558 24.851 1.00 26.31 ? 430 ALA A N 1 ATOM 3012 C CA . ALA A 1 377 ? -41.186 42.666 25.149 1.00 27.47 ? 430 ALA A CA 1 ATOM 3013 C C . ALA A 1 377 ? -41.277 43.828 24.162 1.00 30.16 ? 430 ALA A C 1 ATOM 3014 O O . ALA A 1 377 ? -40.755 44.907 24.440 1.00 30.06 ? 430 ALA A O 1 ATOM 3015 C CB . ALA A 1 377 ? -39.755 42.171 25.243 1.00 27.81 ? 430 ALA A CB 1 ATOM 3016 N N . PHE A 1 378 ? -41.943 43.625 23.025 1.00 34.55 ? 431 PHE A N 1 ATOM 3017 C CA . PHE A 1 378 ? -41.932 44.621 21.946 1.00 36.85 ? 431 PHE A CA 1 ATOM 3018 C C . PHE A 1 378 ? -43.316 45.172 21.590 1.00 40.32 ? 431 PHE A C 1 ATOM 3019 O O . PHE A 1 378 ? -44.242 44.417 21.296 1.00 42.96 ? 431 PHE A O 1 ATOM 3020 C CB . PHE A 1 378 ? -41.286 44.040 20.685 1.00 36.69 ? 431 PHE A CB 1 ATOM 3021 C CG . PHE A 1 378 ? -40.977 45.075 19.642 1.00 34.29 ? 431 PHE A CG 1 ATOM 3022 C CD1 . PHE A 1 378 ? -41.510 44.982 18.372 1.00 32.63 ? 431 PHE A CD1 1 ATOM 3023 C CD2 . PHE A 1 378 ? -40.158 46.151 19.942 1.00 32.34 ? 431 PHE A CD2 1 ATOM 3024 C CE1 . PHE A 1 378 ? -41.235 45.941 17.421 1.00 32.59 ? 431 PHE A CE1 1 ATOM 3025 C CE2 . PHE A 1 378 ? -39.881 47.105 18.998 1.00 31.51 ? 431 PHE A CE2 1 ATOM 3026 C CZ . PHE A 1 378 ? -40.419 47.001 17.733 1.00 31.06 ? 431 PHE A CZ 1 ATOM 3027 N N . ALA A 1 379 ? -43.446 46.495 21.601 1.00 43.61 ? 432 ALA A N 1 ATOM 3028 C CA . ALA A 1 379 ? -44.740 47.136 21.828 1.00 46.49 ? 432 ALA A CA 1 ATOM 3029 C C . ALA A 1 379 ? -45.639 47.072 20.584 1.00 49.20 ? 432 ALA A C 1 ATOM 3030 O O . ALA A 1 379 ? -46.842 46.810 20.686 1.00 48.37 ? 432 ALA A O 1 ATOM 3031 C CB . ALA A 1 379 ? -44.544 48.575 22.273 1.00 46.14 ? 432 ALA A CB 1 ATOM 3032 N N . GLY A 1 380 ? -45.050 47.300 19.412 1.00 50.68 ? 433 GLY A N 1 ATOM 3033 C CA . GLY A 1 380 ? -45.776 47.168 18.160 1.00 49.71 ? 433 GLY A CA 1 ATOM 3034 C C . GLY A 1 380 ? -45.940 48.483 17.419 1.00 49.52 ? 433 GLY A C 1 ATOM 3035 O O . GLY A 1 380 ? -46.175 48.495 16.210 1.00 50.93 ? 433 GLY A O 1 ATOM 3036 N N . GLU A 1 381 ? -45.838 49.592 18.145 1.00 48.65 ? 434 GLU A N 1 ATOM 3037 C CA . GLU A 1 381 ? -45.902 50.918 17.537 1.00 48.32 ? 434 GLU A CA 1 ATOM 3038 C C . GLU A 1 381 ? -44.539 51.602 17.529 1.00 45.55 ? 434 GLU A C 1 ATOM 3039 O O . GLU A 1 381 ? -44.323 52.574 16.803 1.00 43.02 ? 434 GLU A O 1 ATOM 3040 C CB . GLU A 1 381 ? -46.901 51.793 18.287 1.00 51.07 ? 434 GLU A CB 1 ATOM 3041 C CG . GLU A 1 381 ? -48.309 51.760 17.712 1.00 54.29 ? 434 GLU A CG 1 ATOM 3042 C CD . GLU A 1 381 ? -48.926 53.141 17.622 1.00 56.83 ? 434 GLU A CD 1 ATOM 3043 O OE1 . GLU A 1 381 ? -48.597 53.996 18.470 1.00 59.18 ? 434 GLU A OE1 1 ATOM 3044 O OE2 . GLU A 1 381 ? -49.745 53.370 16.706 1.00 60.09 ? 434 GLU A OE2 1 ATOM 3045 N N . SER A 1 382 ? -43.616 51.098 18.336 1.00 41.22 ? 435 SER A N 1 ATOM 3046 C CA . SER A 1 382 ? -42.233 51.502 18.203 1.00 38.79 ? 435 SER A CA 1 ATOM 3047 C C . SER A 1 382 ? -41.902 51.516 16.718 1.00 37.78 ? 435 SER A C 1 ATOM 3048 O O . SER A 1 382 ? -41.182 52.390 16.240 1.00 38.10 ? 435 SER A O 1 ATOM 3049 C CB . SER A 1 382 ? -41.320 50.541 18.957 1.00 39.84 ? 435 SER A CB 1 ATOM 3050 O OG . SER A 1 382 ? -41.330 50.809 20.351 1.00 39.51 ? 435 SER A OG 1 ATOM 3051 N N . LYS A 1 383 ? -42.459 50.556 15.984 1.00 33.72 ? 436 LYS A N 1 ATOM 3052 C CA . LYS A 1 383 ? -41.945 50.211 14.667 1.00 33.72 ? 436 LYS A CA 1 ATOM 3053 C C . LYS A 1 383 ? -42.453 51.172 13.590 1.00 33.19 ? 436 LYS A C 1 ATOM 3054 O O . LYS A 1 383 ? -41.797 51.380 12.580 1.00 33.41 ? 436 LYS A O 1 ATOM 3055 C CB . LYS A 1 383 ? -42.322 48.770 14.304 1.00 33.43 ? 436 LYS A CB 1 ATOM 3056 C CG . LYS A 1 383 ? -42.896 48.620 12.904 1.00 33.94 ? 436 LYS A CG 1 ATOM 3057 C CD . LYS A 1 383 ? -43.081 47.160 12.496 1.00 33.92 ? 436 LYS A CD 1 ATOM 3058 C CE . LYS A 1 383 ? -42.677 46.943 11.035 1.00 33.45 ? 436 LYS A CE 1 ATOM 3059 N NZ . LYS A 1 383 ? -43.852 46.714 10.156 1.00 36.07 ? 436 LYS A NZ 1 ATOM 3060 N N . HIS A 1 384 ? -43.628 51.751 13.812 1.00 33.84 ? 437 HIS A N 1 ATOM 3061 C CA . HIS A 1 384 ? -44.094 52.874 13.008 1.00 33.33 ? 437 HIS A CA 1 ATOM 3062 C C . HIS A 1 384 ? -43.230 54.124 13.180 1.00 28.38 ? 437 HIS A C 1 ATOM 3063 O O . HIS A 1 384 ? -42.933 54.813 12.215 1.00 28.25 ? 437 HIS A O 1 ATOM 3064 C CB . HIS A 1 384 ? -45.538 53.206 13.360 1.00 35.28 ? 437 HIS A CB 1 ATOM 3065 C CG . HIS A 1 384 ? -46.514 52.140 12.976 1.00 38.41 ? 437 HIS A CG 1 ATOM 3066 N ND1 . HIS A 1 384 ? -46.907 51.146 13.844 1.00 38.87 ? 437 HIS A ND1 1 ATOM 3067 C CD2 . HIS A 1 384 ? -47.189 51.921 11.823 1.00 40.33 ? 437 HIS A CD2 1 ATOM 3068 C CE1 . HIS A 1 384 ? -47.776 50.354 13.240 1.00 40.29 ? 437 HIS A CE1 1 ATOM 3069 N NE2 . HIS A 1 384 ? -47.965 50.803 12.012 1.00 39.53 ? 437 HIS A NE2 1 ATOM 3070 N N . VAL A 1 385 ? -42.842 54.429 14.406 1.00 24.95 ? 438 VAL A N 1 ATOM 3071 C CA . VAL A 1 385 ? -42.041 55.617 14.651 1.00 24.90 ? 438 VAL A CA 1 ATOM 3072 C C . VAL A 1 385 ? -40.663 55.452 14.002 1.00 25.59 ? 438 VAL A C 1 ATOM 3073 O O . VAL A 1 385 ? -40.126 56.383 13.395 1.00 24.60 ? 438 VAL A O 1 ATOM 3074 C CB . VAL A 1 385 ? -41.901 55.892 16.158 1.00 26.31 ? 438 VAL A CB 1 ATOM 3075 C CG1 . VAL A 1 385 ? -40.854 56.972 16.414 1.00 24.89 ? 438 VAL A CG1 1 ATOM 3076 C CG2 . VAL A 1 385 ? -43.278 56.278 16.752 1.00 27.49 ? 438 VAL A CG2 1 ATOM 3077 N N . VAL A 1 386 ? -40.112 54.252 14.110 1.00 23.46 ? 439 VAL A N 1 ATOM 3078 C CA . VAL A 1 386 ? -38.836 53.946 13.502 1.00 25.20 ? 439 VAL A CA 1 ATOM 3079 C C . VAL A 1 386 ? -38.893 54.016 11.966 1.00 27.03 ? 439 VAL A C 1 ATOM 3080 O O . VAL A 1 386 ? -38.029 54.643 11.345 1.00 25.71 ? 439 VAL A O 1 ATOM 3081 C CB . VAL A 1 386 ? -38.331 52.574 14.002 1.00 26.35 ? 439 VAL A CB 1 ATOM 3082 C CG1 . VAL A 1 386 ? -37.276 51.998 13.082 1.00 24.10 ? 439 VAL A CG1 1 ATOM 3083 C CG2 . VAL A 1 386 ? -37.782 52.720 15.425 1.00 26.64 ? 439 VAL A CG2 1 ATOM 3084 N N . GLU A 1 387 ? -39.908 53.401 11.357 1.00 29.33 ? 440 GLU A N 1 ATOM 3085 C CA . GLU A 1 387 ? -40.174 53.587 9.918 1.00 31.38 ? 440 GLU A CA 1 ATOM 3086 C C . GLU A 1 387 ? -40.048 55.054 9.501 1.00 31.19 ? 440 GLU A C 1 ATOM 3087 O O . GLU A 1 387 ? -39.432 55.377 8.491 1.00 30.64 ? 440 GLU A O 1 ATOM 3088 C CB . GLU A 1 387 ? -41.583 53.109 9.550 1.00 33.89 ? 440 GLU A CB 1 ATOM 3089 C CG . GLU A 1 387 ? -41.704 51.629 9.226 1.00 37.39 ? 440 GLU A CG 1 ATOM 3090 C CD . GLU A 1 387 ? -43.127 51.118 9.393 1.00 38.66 ? 440 GLU A CD 1 ATOM 3091 O OE1 . GLU A 1 387 ? -43.328 49.886 9.485 1.00 41.61 ? 440 GLU A OE1 1 ATOM 3092 O OE2 . GLU A 1 387 ? -44.049 51.953 9.436 1.00 41.03 ? 440 GLU A OE2 1 ATOM 3093 N N . ASP A 1 388 ? -40.655 55.946 10.272 1.00 29.74 ? 441 ASP A N 1 ATOM 3094 C CA . ASP A 1 388 ? -40.653 57.350 9.909 1.00 31.95 ? 441 ASP A CA 1 ATOM 3095 C C . ASP A 1 388 ? -39.283 58.005 10.112 1.00 28.28 ? 441 ASP A C 1 ATOM 3096 O O . ASP A 1 388 ? -38.866 58.844 9.318 1.00 27.54 ? 441 ASP A O 1 ATOM 3097 C CB . ASP A 1 388 ? -41.708 58.100 10.714 1.00 35.41 ? 441 ASP A CB 1 ATOM 3098 C CG . ASP A 1 388 ? -41.559 59.582 10.591 1.00 38.41 ? 441 ASP A CG 1 ATOM 3099 O OD1 . ASP A 1 388 ? -41.877 60.112 9.511 1.00 44.90 ? 441 ASP A OD1 1 ATOM 3100 O OD2 . ASP A 1 388 ? -41.111 60.301 11.503 1.00 43.32 ? 441 ASP A OD2 1 ATOM 3101 N N . LEU A 1 389 ? -38.587 57.619 11.174 1.00 26.10 ? 442 LEU A N 1 ATOM 3102 C CA . LEU A 1 389 ? -37.206 58.054 11.376 1.00 26.64 ? 442 LEU A CA 1 ATOM 3103 C C . LEU A 1 389 ? -36.320 57.630 10.213 1.00 24.00 ? 442 LEU A C 1 ATOM 3104 O O . LEU A 1 389 ? -35.494 58.405 9.753 1.00 22.40 ? 442 LEU A O 1 ATOM 3105 C CB . LEU A 1 389 ? -36.627 57.474 12.671 1.00 26.42 ? 442 LEU A CB 1 ATOM 3106 C CG . LEU A 1 389 ? -37.296 57.885 13.971 1.00 28.87 ? 442 LEU A CG 1 ATOM 3107 C CD1 . LEU A 1 389 ? -36.669 57.109 15.117 1.00 29.80 ? 442 LEU A CD1 1 ATOM 3108 C CD2 . LEU A 1 389 ? -37.199 59.408 14.200 1.00 27.54 ? 442 LEU A CD2 1 ATOM 3109 N N . ILE A 1 390 ? -36.497 56.397 9.745 1.00 23.96 ? 443 ILE A N 1 ATOM 3110 C CA . ILE A 1 390 ? -35.696 55.889 8.640 1.00 26.17 ? 443 ILE A CA 1 ATOM 3111 C C . ILE A 1 390 ? -35.952 56.662 7.356 1.00 28.04 ? 443 ILE A C 1 ATOM 3112 O O . ILE A 1 390 ? -35.020 56.937 6.597 1.00 30.32 ? 443 ILE A O 1 ATOM 3113 C CB . ILE A 1 390 ? -35.961 54.397 8.422 1.00 26.28 ? 443 ILE A CB 1 ATOM 3114 C CG1 . ILE A 1 390 ? -35.267 53.582 9.510 1.00 25.91 ? 443 ILE A CG1 1 ATOM 3115 C CG2 . ILE A 1 390 ? -35.448 53.960 7.078 1.00 24.85 ? 443 ILE A CG2 1 ATOM 3116 C CD1 . ILE A 1 390 ? -35.421 52.116 9.342 1.00 26.80 ? 443 ILE A CD1 1 ATOM 3117 N N . ALA A 1 391 ? -37.210 57.024 7.121 1.00 28.95 ? 444 ALA A N 1 ATOM 3118 C CA . ALA A 1 391 ? -37.560 57.923 6.029 1.00 27.87 ? 444 ALA A CA 1 ATOM 3119 C C . ALA A 1 391 ? -36.864 59.265 6.180 1.00 29.60 ? 444 ALA A C 1 ATOM 3120 O O . ALA A 1 391 ? -36.346 59.812 5.204 1.00 32.62 ? 444 ALA A O 1 ATOM 3121 C CB . ALA A 1 391 ? -39.060 58.116 5.959 1.00 27.69 ? 444 ALA A CB 1 ATOM 3122 N N . GLN A 1 392 ? -36.838 59.805 7.394 1.00 30.50 ? 445 GLN A N 1 ATOM 3123 C CA . GLN A 1 392 ? -36.199 61.100 7.609 1.00 29.96 ? 445 GLN A CA 1 ATOM 3124 C C . GLN A 1 392 ? -34.714 61.006 7.258 1.00 30.44 ? 445 GLN A C 1 ATOM 3125 O O . GLN A 1 392 ? -34.190 61.812 6.497 1.00 32.80 ? 445 GLN A O 1 ATOM 3126 C CB . GLN A 1 392 ? -36.343 61.552 9.056 1.00 30.47 ? 445 GLN A CB 1 ATOM 3127 C CG . GLN A 1 392 ? -37.587 62.333 9.375 1.00 30.87 ? 445 GLN A CG 1 ATOM 3128 C CD . GLN A 1 392 ? -37.891 62.313 10.868 1.00 34.32 ? 445 GLN A CD 1 ATOM 3129 O OE1 . GLN A 1 392 ? -37.079 62.770 11.671 1.00 33.66 ? 445 GLN A OE1 1 ATOM 3130 N NE2 . GLN A 1 392 ? -39.053 61.765 11.244 1.00 34.70 ? 445 GLN A NE2 1 ATOM 3131 N N . ILE A 1 393 ? -34.034 60.022 7.829 1.00 28.34 ? 446 ILE A N 1 ATOM 3132 C CA . ILE A 1 393 ? -32.596 59.934 7.689 1.00 27.65 ? 446 ILE A CA 1 ATOM 3133 C C . ILE A 1 393 ? -32.193 59.583 6.250 1.00 24.37 ? 446 ILE A C 1 ATOM 3134 O O . ILE A 1 393 ? -31.189 60.072 5.747 1.00 22.23 ? 446 ILE A O 1 ATOM 3135 C CB . ILE A 1 393 ? -32.023 58.918 8.705 1.00 28.02 ? 446 ILE A CB 1 ATOM 3136 C CG1 . ILE A 1 393 ? -31.914 59.564 10.090 1.00 29.48 ? 446 ILE A CG1 1 ATOM 3137 C CG2 . ILE A 1 393 ? -30.644 58.430 8.275 1.00 28.39 ? 446 ILE A CG2 1 ATOM 3138 C CD1 . ILE A 1 393 ? -32.861 59.008 11.079 1.00 30.96 ? 446 ILE A CD1 1 ATOM 3139 N N . ARG A 1 394 ? -32.966 58.740 5.580 1.00 24.76 ? 447 ARG A N 1 ATOM 3140 C CA . ARG A 1 394 ? -32.673 58.447 4.179 1.00 27.29 ? 447 ARG A CA 1 ATOM 3141 C C . ARG A 1 394 ? -32.777 59.703 3.313 1.00 28.07 ? 447 ARG A C 1 ATOM 3142 O O . ARG A 1 394 ? -32.013 59.880 2.364 1.00 26.46 ? 447 ARG A O 1 ATOM 3143 C CB . ARG A 1 394 ? -33.597 57.371 3.634 1.00 27.19 ? 447 ARG A CB 1 ATOM 3144 C CG . ARG A 1 394 ? -33.361 57.081 2.159 1.00 28.07 ? 447 ARG A CG 1 ATOM 3145 C CD . ARG A 1 394 ? -34.608 56.680 1.405 1.00 25.32 ? 447 ARG A CD 1 ATOM 3146 N NE . ARG A 1 394 ? -35.321 55.626 2.103 1.00 25.89 ? 447 ARG A NE 1 ATOM 3147 C CZ . ARG A 1 394 ? -35.238 54.345 1.787 1.00 28.36 ? 447 ARG A CZ 1 ATOM 3148 N NH1 . ARG A 1 394 ? -34.476 53.950 0.776 1.00 32.27 ? 447 ARG A NH1 1 ATOM 3149 N NH2 . ARG A 1 394 ? -35.924 53.451 2.478 1.00 28.92 ? 447 ARG A NH2 1 ATOM 3150 N N . GLU A 1 395 ? -33.717 60.574 3.655 1.00 28.76 ? 448 GLU A N 1 ATOM 3151 C CA . GLU A 1 395 ? -33.906 61.821 2.929 1.00 31.97 ? 448 GLU A CA 1 ATOM 3152 C C . GLU A 1 395 ? -32.714 62.742 3.142 1.00 31.68 ? 448 GLU A C 1 ATOM 3153 O O . GLU A 1 395 ? -32.212 63.339 2.195 1.00 30.01 ? 448 GLU A O 1 ATOM 3154 C CB . GLU A 1 395 ? -35.185 62.505 3.394 1.00 34.96 ? 448 GLU A CB 1 ATOM 3155 C CG . GLU A 1 395 ? -35.507 63.811 2.693 1.00 38.43 ? 448 GLU A CG 1 ATOM 3156 C CD . GLU A 1 395 ? -35.237 63.761 1.205 1.00 40.89 ? 448 GLU A CD 1 ATOM 3157 O OE1 . GLU A 1 395 ? -35.614 62.763 0.556 1.00 41.15 ? 448 GLU A OE1 1 ATOM 3158 O OE2 . GLU A 1 395 ? -34.644 64.734 0.688 1.00 43.48 ? 448 GLU A OE2 1 ATOM 3159 N N . VAL A 1 396 ? -32.264 62.839 4.390 1.00 30.73 ? 449 VAL A N 1 ATOM 3160 C CA . VAL A 1 396 ? -31.104 63.647 4.745 1.00 29.32 ? 449 VAL A CA 1 ATOM 3161 C C . VAL A 1 396 ? -29.854 63.218 3.974 1.00 32.17 ? 449 VAL A C 1 ATOM 3162 O O . VAL A 1 396 ? -29.148 64.045 3.400 1.00 31.47 ? 449 VAL A O 1 ATOM 3163 C CB . VAL A 1 396 ? -30.813 63.546 6.253 1.00 29.89 ? 449 VAL A CB 1 ATOM 3164 C CG1 . VAL A 1 396 ? -29.433 64.113 6.590 1.00 30.69 ? 449 VAL A CG1 1 ATOM 3165 C CG2 . VAL A 1 396 ? -31.878 64.267 7.047 1.00 28.94 ? 449 VAL A CG2 1 ATOM 3166 N N . PHE A 1 397 ? -29.576 61.921 3.955 1.00 32.53 ? 450 PHE A N 1 ATOM 3167 C CA . PHE A 1 397 ? -28.448 61.419 3.187 1.00 33.59 ? 450 PHE A CA 1 ATOM 3168 C C . PHE A 1 397 ? -28.500 61.987 1.770 1.00 34.98 ? 450 PHE A C 1 ATOM 3169 O O . PHE A 1 397 ? -27.557 62.640 1.312 1.00 34.94 ? 450 PHE A O 1 ATOM 3170 C CB . PHE A 1 397 ? -28.479 59.898 3.155 1.00 32.43 ? 450 PHE A CB 1 ATOM 3171 C CG . PHE A 1 397 ? -27.432 59.280 2.281 1.00 33.33 ? 450 PHE A CG 1 ATOM 3172 C CD1 . PHE A 1 397 ? -27.677 59.072 0.938 1.00 34.12 ? 450 PHE A CD1 1 ATOM 3173 C CD2 . PHE A 1 397 ? -26.215 58.881 2.806 1.00 33.21 ? 450 PHE A CD2 1 ATOM 3174 C CE1 . PHE A 1 397 ? -26.732 58.481 0.136 1.00 34.27 ? 450 PHE A CE1 1 ATOM 3175 C CE2 . PHE A 1 397 ? -25.262 58.290 2.006 1.00 33.67 ? 450 PHE A CE2 1 ATOM 3176 C CZ . PHE A 1 397 ? -25.521 58.086 0.671 1.00 35.00 ? 450 PHE A CZ 1 ATOM 3177 N N . ILE A 1 398 ? -29.618 61.748 1.091 1.00 33.33 ? 451 ILE A N 1 ATOM 3178 C CA . ILE A 1 398 ? -29.844 62.270 -0.255 1.00 32.69 ? 451 ILE A CA 1 ATOM 3179 C C . ILE A 1 398 ? -29.529 63.762 -0.366 1.00 30.03 ? 451 ILE A C 1 ATOM 3180 O O . ILE A 1 398 ? -28.702 64.165 -1.186 1.00 26.81 ? 451 ILE A O 1 ATOM 3181 C CB . ILE A 1 398 ? -31.292 62.009 -0.669 1.00 32.16 ? 451 ILE A CB 1 ATOM 3182 C CG1 . ILE A 1 398 ? -31.563 60.511 -0.680 1.00 31.52 ? 451 ILE A CG1 1 ATOM 3183 C CG2 . ILE A 1 398 ? -31.576 62.590 -2.042 1.00 33.50 ? 451 ILE A CG2 1 ATOM 3184 C CD1 . ILE A 1 398 ? -33.018 60.182 -0.735 1.00 32.04 ? 451 ILE A CD1 1 ATOM 3185 N N . GLN A 1 399 ? -30.179 64.561 0.474 1.00 28.59 ? 452 GLN A N 1 ATOM 3186 C CA . GLN A 1 399 ? -29.896 65.989 0.594 1.00 32.08 ? 452 GLN A CA 1 ATOM 3187 C C . GLN A 1 399 ? -28.402 66.290 0.506 1.00 31.05 ? 452 GLN A C 1 ATOM 3188 O O . GLN A 1 399 ? -27.962 67.096 -0.327 1.00 33.23 ? 452 GLN A O 1 ATOM 3189 C CB . GLN A 1 399 ? -30.431 66.530 1.930 1.00 37.25 ? 452 GLN A CB 1 ATOM 3190 C CG . GLN A 1 399 ? -31.932 66.798 1.952 1.00 41.28 ? 452 GLN A CG 1 ATOM 3191 C CD . GLN A 1 399 ? -32.413 67.456 3.243 1.00 44.21 ? 452 GLN A CD 1 ATOM 3192 O OE1 . GLN A 1 399 ? -31.648 67.603 4.206 1.00 45.19 ? 452 GLN A OE1 1 ATOM 3193 N NE2 . GLN A 1 399 ? -33.681 67.857 3.260 1.00 44.34 ? 452 GLN A NE2 1 ATOM 3194 N N . THR A 1 400 ? -27.638 65.660 1.394 1.00 26.97 ? 453 THR A N 1 ATOM 3195 C CA . THR A 1 400 ? -26.259 66.033 1.687 1.00 25.29 ? 453 THR A CA 1 ATOM 3196 C C . THR A 1 400 ? -25.408 65.779 0.455 1.00 23.42 ? 453 THR A C 1 ATOM 3197 O O . THR A 1 400 ? -24.343 66.341 0.291 1.00 22.92 ? 453 THR A O 1 ATOM 3198 C CB . THR A 1 400 ? -25.761 65.182 2.887 1.00 22.40 ? 453 THR A CB 1 ATOM 3199 O OG1 . THR A 1 400 ? -26.545 65.495 4.039 1.00 21.94 ? 453 THR A OG1 1 ATOM 3200 C CG2 . THR A 1 400 ? -24.335 65.536 3.291 1.00 21.16 ? 453 THR A CG2 1 ATOM 3201 N N . LEU A 1 401 ? -25.898 64.896 -0.401 1.00 28.61 ? 454 LEU A N 1 ATOM 3202 C CA . LEU A 1 401 ? -25.229 64.605 -1.656 1.00 32.01 ? 454 LEU A CA 1 ATOM 3203 C C . LEU A 1 401 ? -24.921 65.907 -2.393 1.00 36.84 ? 454 LEU A C 1 ATOM 3204 O O . LEU A 1 401 ? -23.940 65.990 -3.132 1.00 38.70 ? 454 LEU A O 1 ATOM 3205 C CB . LEU A 1 401 ? -26.085 63.680 -2.519 1.00 28.48 ? 454 LEU A CB 1 ATOM 3206 C CG . LEU A 1 401 ? -26.146 62.234 -2.022 1.00 29.42 ? 454 LEU A CG 1 ATOM 3207 C CD1 . LEU A 1 401 ? -26.967 61.357 -2.948 1.00 29.09 ? 454 LEU A CD1 1 ATOM 3208 C CD2 . LEU A 1 401 ? -24.744 61.648 -1.843 1.00 29.68 ? 454 LEU A CD2 1 ATOM 3209 N N . ASP A 1 402 ? -25.743 66.927 -2.171 1.00 39.54 ? 455 ASP A N 1 ATOM 3210 C CA . ASP A 1 402 ? -25.585 68.188 -2.883 1.00 43.11 ? 455 ASP A CA 1 ATOM 3211 C C . ASP A 1 402 ? -24.425 69.004 -2.332 1.00 42.68 ? 455 ASP A C 1 ATOM 3212 O O . ASP A 1 402 ? -23.784 69.743 -3.073 1.00 44.41 ? 455 ASP A O 1 ATOM 3213 C CB . ASP A 1 402 ? -26.875 69.009 -2.830 1.00 45.74 ? 455 ASP A CB 1 ATOM 3214 C CG . ASP A 1 402 ? -28.066 68.261 -3.404 1.00 48.43 ? 455 ASP A CG 1 ATOM 3215 O OD1 . ASP A 1 402 ? -28.019 67.013 -3.464 1.00 50.94 ? 455 ASP A OD1 1 ATOM 3216 O OD2 . ASP A 1 402 ? -29.102 68.834 -3.805 1.00 50.28 ? 455 ASP A OD2 1 ATOM 3217 N N . ASP A 1 403 ? -24.148 68.866 -1.040 1.00 42.22 ? 456 ASP A N 1 ATOM 3218 C CA . ASP A 1 403 ? -23.160 69.715 -0.377 1.00 43.31 ? 456 ASP A CA 1 ATOM 3219 C C . ASP A 1 403 ? -21.793 69.034 -0.330 1.00 42.07 ? 456 ASP A C 1 ATOM 3220 O O . ASP A 1 403 ? -20.821 69.593 0.185 1.00 43.32 ? 456 ASP A O 1 ATOM 3221 C CB . ASP A 1 403 ? -23.610 70.064 1.043 1.00 45.35 ? 456 ASP A CB 1 ATOM 3222 C CG . ASP A 1 403 ? -24.709 71.105 1.069 1.00 48.34 ? 456 ASP A CG 1 ATOM 3223 O OD1 . ASP A 1 403 ? -24.411 72.286 0.763 1.00 51.02 ? 456 ASP A OD1 1 ATOM 3224 O OD2 . ASP A 1 403 ? -25.889 70.841 1.391 1.00 46.66 ? 456 ASP A OD2 1 ATOM 3225 N N . LEU A 1 404 ? -21.719 67.827 -0.872 1.00 38.03 ? 457 LEU A N 1 ATOM 3226 C CA . LEU A 1 404 ? -20.485 67.068 -0.833 1.00 37.39 ? 457 LEU A CA 1 ATOM 3227 C C . LEU A 1 404 ? -19.653 67.369 -2.067 1.00 37.03 ? 457 LEU A C 1 ATOM 3228 O O . LEU A 1 404 ? -20.047 67.014 -3.182 1.00 36.09 ? 457 LEU A O 1 ATOM 3229 C CB . LEU A 1 404 ? -20.795 65.575 -0.765 1.00 36.57 ? 457 LEU A CB 1 ATOM 3230 C CG . LEU A 1 404 ? -21.580 65.160 0.481 1.00 35.41 ? 457 LEU A CG 1 ATOM 3231 C CD1 . LEU A 1 404 ? -21.545 63.657 0.654 1.00 35.43 ? 457 LEU A CD1 1 ATOM 3232 C CD2 . LEU A 1 404 ? -21.027 65.855 1.717 1.00 34.52 ? 457 LEU A CD2 1 ATOM 3233 N N . THR A 1 405 ? -18.507 68.022 -1.871 1.00 35.54 ? 458 THR A N 1 ATOM 3234 C CA . THR A 1 405 ? -17.778 68.629 -2.985 1.00 35.83 ? 458 THR A CA 1 ATOM 3235 C C . THR A 1 405 ? -16.843 67.646 -3.700 1.00 35.24 ? 458 THR A C 1 ATOM 3236 O O . THR A 1 405 ? -16.178 68.019 -4.662 1.00 37.98 ? 458 THR A O 1 ATOM 3237 C CB . THR A 1 405 ? -16.979 69.865 -2.514 1.00 35.98 ? 458 THR A CB 1 ATOM 3238 O OG1 . THR A 1 405 ? -16.092 69.512 -1.452 1.00 37.34 ? 458 THR A OG1 1 ATOM 3239 C CG2 . THR A 1 405 ? -17.897 70.906 -1.889 1.00 36.87 ? 458 THR A CG2 1 ATOM 3240 N N . TRP A 1 406 ? -16.801 66.394 -3.253 1.00 31.41 ? 459 TRP A N 1 ATOM 3241 C CA . TRP A 1 406 ? -15.779 65.468 -3.722 1.00 28.82 ? 459 TRP A CA 1 ATOM 3242 C C . TRP A 1 406 ? -16.352 64.406 -4.651 1.00 28.56 ? 459 TRP A C 1 ATOM 3243 O O . TRP A 1 406 ? -15.639 63.507 -5.095 1.00 28.32 ? 459 TRP A O 1 ATOM 3244 C CB . TRP A 1 406 ? -15.038 64.824 -2.542 1.00 27.94 ? 459 TRP A CB 1 ATOM 3245 C CG . TRP A 1 406 ? -15.932 64.174 -1.528 1.00 25.69 ? 459 TRP A CG 1 ATOM 3246 C CD1 . TRP A 1 406 ? -16.391 64.726 -0.370 1.00 24.79 ? 459 TRP A CD1 1 ATOM 3247 C CD2 . TRP A 1 406 ? -16.454 62.846 -1.572 1.00 23.52 ? 459 TRP A CD2 1 ATOM 3248 N NE1 . TRP A 1 406 ? -17.182 63.826 0.303 1.00 26.55 ? 459 TRP A NE1 1 ATOM 3249 C CE2 . TRP A 1 406 ? -17.235 62.661 -0.414 1.00 24.67 ? 459 TRP A CE2 1 ATOM 3250 C CE3 . TRP A 1 406 ? -16.351 61.792 -2.479 1.00 23.54 ? 459 TRP A CE3 1 ATOM 3251 C CZ2 . TRP A 1 406 ? -17.906 61.475 -0.145 1.00 23.87 ? 459 TRP A CZ2 1 ATOM 3252 C CZ3 . TRP A 1 406 ? -17.018 60.610 -2.210 1.00 25.77 ? 459 TRP A CZ3 1 ATOM 3253 C CH2 . TRP A 1 406 ? -17.792 60.465 -1.055 1.00 25.55 ? 459 TRP A CH2 1 ATOM 3254 N N . MET A 1 407 ? -17.636 64.522 -4.967 1.00 30.99 ? 460 MET A N 1 ATOM 3255 C CA . MET A 1 407 ? -18.235 63.694 -6.003 1.00 32.49 ? 460 MET A CA 1 ATOM 3256 C C . MET A 1 407 ? -18.598 64.542 -7.207 1.00 32.33 ? 460 MET A C 1 ATOM 3257 O O . MET A 1 407 ? -18.791 65.744 -7.089 1.00 30.64 ? 460 MET A O 1 ATOM 3258 C CB . MET A 1 407 ? -19.493 62.994 -5.483 1.00 33.19 ? 460 MET A CB 1 ATOM 3259 C CG . MET A 1 407 ? -19.299 62.239 -4.171 1.00 34.17 ? 460 MET A CG 1 ATOM 3260 S SD . MET A 1 407 ? -20.731 61.242 -3.764 1.00 32.78 ? 460 MET A SD 1 ATOM 3261 C CE . MET A 1 407 ? -20.655 60.081 -5.028 1.00 34.53 ? 460 MET A CE 1 ATOM 3262 N N . ASP A 1 408 ? -18.697 63.895 -8.362 1.00 33.70 ? 461 ASP A N 1 ATOM 3263 C CA . ASP A 1 408 ? -19.187 64.537 -9.569 1.00 33.21 ? 461 ASP A CA 1 ATOM 3264 C C . ASP A 1 408 ? -20.670 64.265 -9.720 1.00 34.66 ? 461 ASP A C 1 ATOM 3265 O O . ASP A 1 408 ? -21.218 63.356 -9.095 1.00 32.91 ? 461 ASP A O 1 ATOM 3266 C CB . ASP A 1 408 ? -18.441 64.021 -10.801 1.00 32.54 ? 461 ASP A CB 1 ATOM 3267 C CG . ASP A 1 408 ? -18.483 62.504 -10.917 1.00 31.88 ? 461 ASP A CG 1 ATOM 3268 O OD1 . ASP A 1 408 ? -17.500 61.895 -11.392 1.00 30.47 ? 461 ASP A OD1 1 ATOM 3269 O OD2 . ASP A 1 408 ? -19.466 61.836 -10.557 1.00 30.61 ? 461 ASP A OD2 1 ATOM 3270 N N . ALA A 1 409 ? -21.307 65.072 -10.561 1.00 36.22 ? 462 ALA A N 1 ATOM 3271 C CA . ALA A 1 409 ? -22.749 65.078 -10.708 1.00 36.42 ? 462 ALA A CA 1 ATOM 3272 C C . ALA A 1 409 ? -23.294 63.686 -10.958 1.00 35.74 ? 462 ALA A C 1 ATOM 3273 O O . ALA A 1 409 ? -24.186 63.231 -10.253 1.00 39.89 ? 462 ALA A O 1 ATOM 3274 C CB . ALA A 1 409 ? -23.159 66.011 -11.848 1.00 37.25 ? 462 ALA A CB 1 ATOM 3275 N N . GLU A 1 410 ? -22.798 63.003 -11.973 1.00 35.73 ? 463 GLU A N 1 ATOM 3276 C CA . GLU A 1 410 ? -23.387 61.709 -12.291 1.00 36.94 ? 463 GLU A CA 1 ATOM 3277 C C . GLU A 1 410 ? -23.297 60.794 -11.075 1.00 36.66 ? 463 GLU A C 1 ATOM 3278 O O . GLU A 1 410 ? -24.206 60.008 -10.808 1.00 39.20 ? 463 GLU A O 1 ATOM 3279 C CB . GLU A 1 410 ? -22.708 61.053 -13.487 1.00 37.41 ? 463 GLU A CB 1 ATOM 3280 C CG . GLU A 1 410 ? -21.245 61.415 -13.670 1.00 40.09 ? 463 GLU A CG 1 ATOM 3281 C CD . GLU A 1 410 ? -20.688 60.872 -14.976 1.00 42.21 ? 463 GLU A CD 1 ATOM 3282 O OE1 . GLU A 1 410 ? -20.143 61.668 -15.773 1.00 42.48 ? 463 GLU A OE1 1 ATOM 3283 O OE2 . GLU A 1 410 ? -20.815 59.648 -15.210 1.00 43.00 ? 463 GLU A OE2 1 ATOM 3284 N N . THR A 1 411 ? -22.188 60.880 -10.350 1.00 34.28 ? 464 THR A N 1 ATOM 3285 C CA . THR A 1 411 ? -21.938 59.949 -9.262 1.00 34.12 ? 464 THR A CA 1 ATOM 3286 C C . THR A 1 411 ? -22.942 60.204 -8.141 1.00 33.67 ? 464 THR A C 1 ATOM 3287 O O . THR A 1 411 ? -23.577 59.275 -7.641 1.00 32.83 ? 464 THR A O 1 ATOM 3288 C CB . THR A 1 411 ? -20.475 60.062 -8.756 1.00 32.49 ? 464 THR A CB 1 ATOM 3289 O OG1 . THR A 1 411 ? -19.579 59.487 -9.722 1.00 28.37 ? 464 THR A OG1 1 ATOM 3290 C CG2 . THR A 1 411 ? -20.255 59.211 -7.489 1.00 31.72 ? 464 THR A CG2 1 ATOM 3291 N N . LYS A 1 412 ? -23.113 61.470 -7.777 1.00 33.93 ? 465 LYS A N 1 ATOM 3292 C CA . LYS A 1 412 ? -24.175 61.849 -6.853 1.00 32.74 ? 465 LYS A CA 1 ATOM 3293 C C . LYS A 1 412 ? -25.478 61.172 -7.251 1.00 35.23 ? 465 LYS A C 1 ATOM 3294 O O . LYS A 1 412 ? -26.136 60.535 -6.421 1.00 31.10 ? 465 LYS A O 1 ATOM 3295 C CB . LYS A 1 412 ? -24.350 63.367 -6.812 1.00 31.12 ? 465 LYS A CB 1 ATOM 3296 C CG . LYS A 1 412 ? -23.236 64.069 -6.068 1.00 30.73 ? 465 LYS A CG 1 ATOM 3297 C CD . LYS A 1 412 ? -23.383 65.587 -6.030 1.00 30.26 ? 465 LYS A CD 1 ATOM 3298 C CE . LYS A 1 412 ? -22.162 66.208 -5.360 1.00 29.35 ? 465 LYS A CE 1 ATOM 3299 N NZ . LYS A 1 412 ? -22.318 67.634 -4.968 1.00 28.74 ? 465 LYS A NZ 1 ATOM 3300 N N . LYS A 1 413 ? -25.838 61.294 -8.525 1.00 36.59 ? 466 LYS A N 1 ATOM 3301 C CA . LYS A 1 413 ? -27.148 60.847 -8.985 1.00 39.31 ? 466 LYS A CA 1 ATOM 3302 C C . LYS A 1 413 ? -27.322 59.365 -8.721 1.00 37.71 ? 466 LYS A C 1 ATOM 3303 O O . LYS A 1 413 ? -28.363 58.923 -8.252 1.00 37.76 ? 466 LYS A O 1 ATOM 3304 C CB . LYS A 1 413 ? -27.324 61.114 -10.481 1.00 41.47 ? 466 LYS A CB 1 ATOM 3305 C CG . LYS A 1 413 ? -28.508 60.378 -11.107 1.00 43.16 ? 466 LYS A CG 1 ATOM 3306 C CD . LYS A 1 413 ? -28.701 60.767 -12.579 1.00 46.26 ? 466 LYS A CD 1 ATOM 3307 C CE . LYS A 1 413 ? -28.389 62.251 -12.830 1.00 46.53 ? 466 LYS A CE 1 ATOM 3308 N NZ . LYS A 1 413 ? -29.147 62.811 -13.997 1.00 47.80 ? 466 LYS A NZ 1 ATOM 3309 N N . ARG A 1 414 ? -26.299 58.591 -9.034 1.00 38.01 ? 467 ARG A N 1 ATOM 3310 C CA . ARG A 1 414 ? -26.362 57.164 -8.795 1.00 38.92 ? 467 ARG A CA 1 ATOM 3311 C C . ARG A 1 414 ? -26.425 56.881 -7.300 1.00 37.26 ? 467 ARG A C 1 ATOM 3312 O O . ARG A 1 414 ? -27.063 55.926 -6.874 1.00 36.40 ? 467 ARG A O 1 ATOM 3313 C CB . ARG A 1 414 ? -25.163 56.468 -9.417 1.00 43.33 ? 467 ARG A CB 1 ATOM 3314 C CG . ARG A 1 414 ? -25.483 55.817 -10.752 1.00 47.69 ? 467 ARG A CG 1 ATOM 3315 C CD . ARG A 1 414 ? -24.454 56.101 -11.805 1.00 50.95 ? 467 ARG A CD 1 ATOM 3316 N NE . ARG A 1 414 ? -24.595 55.236 -12.967 1.00 55.24 ? 467 ARG A NE 1 ATOM 3317 C CZ . ARG A 1 414 ? -23.779 55.283 -14.011 1.00 58.86 ? 467 ARG A CZ 1 ATOM 3318 N NH1 . ARG A 1 414 ? -22.776 56.154 -14.022 1.00 59.45 ? 467 ARG A NH1 1 ATOM 3319 N NH2 . ARG A 1 414 ? -23.961 54.467 -15.043 1.00 59.71 ? 467 ARG A NH2 1 ATOM 3320 N N . ALA A 1 415 ? -25.766 57.719 -6.511 1.00 33.20 ? 468 ALA A N 1 ATOM 3321 C CA . ALA A 1 415 ? -25.768 57.551 -5.075 1.00 32.69 ? 468 ALA A CA 1 ATOM 3322 C C . ALA A 1 415 ? -27.176 57.731 -4.532 1.00 34.61 ? 468 ALA A C 1 ATOM 3323 O O . ALA A 1 415 ? -27.600 57.001 -3.636 1.00 35.81 ? 468 ALA A O 1 ATOM 3324 C CB . ALA A 1 415 ? -24.821 58.538 -4.424 1.00 29.54 ? 468 ALA A CB 1 ATOM 3325 N N . GLU A 1 416 ? -27.896 58.705 -5.077 1.00 35.14 ? 469 GLU A N 1 ATOM 3326 C CA . GLU A 1 416 ? -29.279 58.941 -4.689 1.00 35.92 ? 469 GLU A CA 1 ATOM 3327 C C . GLU A 1 416 ? -30.136 57.758 -5.118 1.00 35.54 ? 469 GLU A C 1 ATOM 3328 O O . GLU A 1 416 ? -30.922 57.211 -4.339 1.00 30.67 ? 469 GLU A O 1 ATOM 3329 C CB . GLU A 1 416 ? -29.792 60.232 -5.327 1.00 34.89 ? 469 GLU A CB 1 ATOM 3330 C CG . GLU A 1 416 ? -31.295 60.278 -5.551 1.00 34.66 ? 469 GLU A CG 1 ATOM 3331 C CD . GLU A 1 416 ? -31.783 61.672 -5.892 1.00 35.13 ? 469 GLU A CD 1 ATOM 3332 O OE1 . GLU A 1 416 ? -33.009 61.892 -5.873 1.00 38.87 ? 469 GLU A OE1 1 ATOM 3333 O OE2 . GLU A 1 416 ? -30.945 62.556 -6.167 1.00 34.48 ? 469 GLU A OE2 1 ATOM 3334 N N . GLU A 1 417 ? -29.950 57.362 -6.369 1.00 35.76 ? 470 GLU A N 1 ATOM 3335 C CA . GLU A 1 417 ? -30.511 56.123 -6.876 1.00 35.23 ? 470 GLU A CA 1 ATOM 3336 C C . GLU A 1 417 ? -30.453 55.011 -5.841 1.00 32.60 ? 470 GLU A C 1 ATOM 3337 O O . GLU A 1 417 ? -31.489 54.515 -5.400 1.00 29.41 ? 470 GLU A O 1 ATOM 3338 C CB . GLU A 1 417 ? -29.761 55.694 -8.122 1.00 35.89 ? 470 GLU A CB 1 ATOM 3339 C CG . GLU A 1 417 ? -30.656 55.454 -9.319 1.00 39.59 ? 470 GLU A CG 1 ATOM 3340 C CD . GLU A 1 417 ? -29.902 55.608 -10.627 1.00 39.05 ? 470 GLU A CD 1 ATOM 3341 O OE1 . GLU A 1 417 ? -29.871 56.737 -11.158 1.00 36.83 ? 470 GLU A OE1 1 ATOM 3342 O OE2 . GLU A 1 417 ? -29.333 54.600 -11.103 1.00 38.54 ? 470 GLU A OE2 1 ATOM 3343 N N . LYS A 1 418 ? -29.238 54.615 -5.473 1.00 31.00 ? 471 LYS A N 1 ATOM 3344 C CA . LYS A 1 418 ? -29.039 53.424 -4.655 1.00 30.55 ? 471 LYS A CA 1 ATOM 3345 C C . LYS A 1 418 ? -29.727 53.616 -3.311 1.00 28.37 ? 471 LYS A C 1 ATOM 3346 O O . LYS A 1 418 ? -30.260 52.678 -2.740 1.00 31.46 ? 471 LYS A O 1 ATOM 3347 C CB . LYS A 1 418 ? -27.553 53.154 -4.424 1.00 30.20 ? 471 LYS A CB 1 ATOM 3348 C CG . LYS A 1 418 ? -27.293 52.291 -3.199 1.00 30.38 ? 471 LYS A CG 1 ATOM 3349 C CD . LYS A 1 418 ? -26.102 51.364 -3.357 1.00 29.38 ? 471 LYS A CD 1 ATOM 3350 C CE . LYS A 1 418 ? -25.926 50.485 -2.122 1.00 29.47 ? 471 LYS A CE 1 ATOM 3351 N NZ . LYS A 1 418 ? -24.977 49.334 -2.310 1.00 28.54 ? 471 LYS A NZ 1 ATOM 3352 N N . ALA A 1 419 ? -29.704 54.850 -2.828 1.00 27.15 ? 472 ALA A N 1 ATOM 3353 C CA . ALA A 1 419 ? -30.277 55.199 -1.548 1.00 26.96 ? 472 ALA A CA 1 ATOM 3354 C C . ALA A 1 419 ? -31.798 55.081 -1.571 1.00 30.22 ? 472 ALA A C 1 ATOM 3355 O O . ALA A 1 419 ? -32.397 54.539 -0.639 1.00 30.55 ? 472 ALA A O 1 ATOM 3356 C CB . ALA A 1 419 ? -29.874 56.595 -1.188 1.00 26.04 ? 472 ALA A CB 1 ATOM 3357 N N . LEU A 1 420 ? -32.423 55.581 -2.635 1.00 28.90 ? 473 LEU A N 1 ATOM 3358 C CA . LEU A 1 420 ? -33.864 55.423 -2.806 1.00 28.26 ? 473 LEU A CA 1 ATOM 3359 C C . LEU A 1 420 ? -34.227 53.948 -2.782 1.00 28.50 ? 473 LEU A C 1 ATOM 3360 O O . LEU A 1 420 ? -35.339 53.565 -2.401 1.00 30.37 ? 473 LEU A O 1 ATOM 3361 C CB . LEU A 1 420 ? -34.339 56.077 -4.111 1.00 27.37 ? 473 LEU A CB 1 ATOM 3362 C CG . LEU A 1 420 ? -34.231 57.601 -4.098 1.00 27.48 ? 473 LEU A CG 1 ATOM 3363 C CD1 . LEU A 1 420 ? -34.172 58.181 -5.522 1.00 28.23 ? 473 LEU A CD1 1 ATOM 3364 C CD2 . LEU A 1 420 ? -35.387 58.195 -3.295 1.00 27.91 ? 473 LEU A CD2 1 ATOM 3365 N N . ALA A 1 421 ? -33.272 53.115 -3.162 1.00 27.17 ? 474 ALA A N 1 ATOM 3366 C CA . ALA A 1 421 ? -33.536 51.702 -3.374 1.00 27.78 ? 474 ALA A CA 1 ATOM 3367 C C . ALA A 1 421 ? -33.318 50.872 -2.103 1.00 27.13 ? 474 ALA A C 1 ATOM 3368 O O . ALA A 1 421 ? -33.616 49.676 -2.074 1.00 25.85 ? 474 ALA A O 1 ATOM 3369 C CB . ALA A 1 421 ? -32.656 51.184 -4.490 1.00 29.45 ? 474 ALA A CB 1 ATOM 3370 N N . ILE A 1 422 ? -32.803 51.492 -1.052 1.00 26.76 ? 475 ILE A N 1 ATOM 3371 C CA . ILE A 1 422 ? -32.645 50.761 0.197 1.00 29.60 ? 475 ILE A CA 1 ATOM 3372 C C . ILE A 1 422 ? -33.998 50.353 0.732 1.00 28.42 ? 475 ILE A C 1 ATOM 3373 O O . ILE A 1 422 ? -34.947 51.135 0.737 1.00 30.47 ? 475 ILE A O 1 ATOM 3374 C CB . ILE A 1 422 ? -31.933 51.612 1.248 1.00 29.46 ? 475 ILE A CB 1 ATOM 3375 C CG1 . ILE A 1 422 ? -30.624 52.169 0.684 1.00 29.10 ? 475 ILE A CG1 1 ATOM 3376 C CG2 . ILE A 1 422 ? -31.666 50.800 2.507 1.00 29.56 ? 475 ILE A CG2 1 ATOM 3377 C CD1 . ILE A 1 422 ? -29.683 52.708 1.740 1.00 29.31 ? 475 ILE A CD1 1 ATOM 3378 N N . LYS A 1 423 ? -34.076 49.129 1.211 1.00 30.25 ? 476 LYS A N 1 ATOM 3379 C CA . LYS A 1 423 ? -35.326 48.630 1.731 1.00 34.48 ? 476 LYS A CA 1 ATOM 3380 C C . LYS A 1 423 ? -35.122 48.155 3.157 1.00 33.98 ? 476 LYS A C 1 ATOM 3381 O O . LYS A 1 423 ? -34.125 47.508 3.473 1.00 35.59 ? 476 LYS A O 1 ATOM 3382 C CB . LYS A 1 423 ? -35.846 47.501 0.851 1.00 37.60 ? 476 LYS A CB 1 ATOM 3383 C CG . LYS A 1 423 ? -37.020 47.892 -0.040 1.00 41.93 ? 476 LYS A CG 1 ATOM 3384 C CD . LYS A 1 423 ? -38.287 47.058 0.267 1.00 45.03 ? 476 LYS A CD 1 ATOM 3385 C CE . LYS A 1 423 ? -38.123 45.578 -0.061 1.00 46.19 ? 476 LYS A CE 1 ATOM 3386 N NZ . LYS A 1 423 ? -39.440 44.883 -0.141 1.00 48.30 ? 476 LYS A NZ 1 ATOM 3387 N N . GLU A 1 424 ? -36.067 48.508 4.015 1.00 31.47 ? 477 GLU A N 1 ATOM 3388 C CA . GLU A 1 424 ? -35.808 48.608 5.437 1.00 31.43 ? 477 GLU A CA 1 ATOM 3389 C C . GLU A 1 424 ? -36.569 47.505 6.141 1.00 30.37 ? 477 GLU A C 1 ATOM 3390 O O . GLU A 1 424 ? -37.665 47.135 5.717 1.00 31.50 ? 477 GLU A O 1 ATOM 3391 C CB . GLU A 1 424 ? -36.224 49.981 5.968 1.00 32.77 ? 477 GLU A CB 1 ATOM 3392 C CG . GLU A 1 424 ? -37.722 50.156 6.157 1.00 34.29 ? 477 GLU A CG 1 ATOM 3393 C CD . GLU A 1 424 ? -38.289 51.299 5.337 1.00 36.77 ? 477 GLU A CD 1 ATOM 3394 O OE1 . GLU A 1 424 ? -38.439 52.414 5.884 1.00 39.20 ? 477 GLU A OE1 1 ATOM 3395 O OE2 . GLU A 1 424 ? -38.595 51.083 4.143 1.00 38.78 ? 477 GLU A OE2 1 ATOM 3396 N N . ARG A 1 425 ? -35.967 46.970 7.200 1.00 27.85 ? 478 ARG A N 1 ATOM 3397 C CA . ARG A 1 425 ? -36.521 45.843 7.935 1.00 27.20 ? 478 ARG A CA 1 ATOM 3398 C C . ARG A 1 425 ? -36.558 46.222 9.395 1.00 24.65 ? 478 ARG A C 1 ATOM 3399 O O . ARG A 1 425 ? -35.514 46.444 10.000 1.00 19.81 ? 478 ARG A O 1 ATOM 3400 C CB . ARG A 1 425 ? -35.630 44.617 7.794 1.00 30.19 ? 478 ARG A CB 1 ATOM 3401 C CG . ARG A 1 425 ? -35.426 44.188 6.381 1.00 34.76 ? 478 ARG A CG 1 ATOM 3402 C CD . ARG A 1 425 ? -36.672 43.642 5.764 1.00 37.64 ? 478 ARG A CD 1 ATOM 3403 N NE . ARG A 1 425 ? -36.378 42.582 4.818 1.00 41.19 ? 478 ARG A NE 1 ATOM 3404 C CZ . ARG A 1 425 ? -37.218 42.188 3.881 1.00 43.14 ? 478 ARG A CZ 1 ATOM 3405 N NH1 . ARG A 1 425 ? -38.406 42.773 3.777 1.00 42.82 ? 478 ARG A NH1 1 ATOM 3406 N NH2 . ARG A 1 425 ? -36.872 41.214 3.049 1.00 44.00 ? 478 ARG A NH2 1 ATOM 3407 N N . ILE A 1 426 ? -37.752 46.296 9.962 1.00 23.95 ? 479 ILE A N 1 ATOM 3408 C CA . ILE A 1 426 ? -37.928 46.972 11.236 1.00 24.22 ? 479 ILE A CA 1 ATOM 3409 C C . ILE A 1 426 ? -38.592 46.044 12.223 1.00 23.37 ? 479 ILE A C 1 ATOM 3410 O O . ILE A 1 426 ? -39.722 45.617 12.012 1.00 26.84 ? 479 ILE A O 1 ATOM 3411 C CB . ILE A 1 426 ? -38.760 48.250 11.058 1.00 22.33 ? 479 ILE A CB 1 ATOM 3412 C CG1 . ILE A 1 426 ? -38.167 49.110 9.949 1.00 23.65 ? 479 ILE A CG1 1 ATOM 3413 C CG2 . ILE A 1 426 ? -38.781 49.039 12.332 1.00 22.30 ? 479 ILE A CG2 1 ATOM 3414 C CD1 . ILE A 1 426 ? -39.168 50.000 9.278 1.00 24.21 ? 479 ILE A CD1 1 ATOM 3415 N N . GLY A 1 427 ? -37.884 45.726 13.300 1.00 23.87 ? 480 GLY A N 1 ATOM 3416 C CA . GLY A 1 427 ? -38.501 45.086 14.452 1.00 20.98 ? 480 GLY A CA 1 ATOM 3417 C C . GLY A 1 427 ? -38.523 43.583 14.302 1.00 20.65 ? 480 GLY A C 1 ATOM 3418 O O . GLY A 1 427 ? -37.653 42.889 14.822 1.00 19.17 ? 480 GLY A O 1 ATOM 3419 N N . TYR A 1 428 ? -39.512 43.081 13.570 1.00 21.03 ? 481 TYR A N 1 ATOM 3420 C CA . TYR A 1 428 ? -39.606 41.655 13.266 1.00 20.94 ? 481 TYR A CA 1 ATOM 3421 C C . TYR A 1 428 ? -40.480 41.485 12.039 1.00 20.10 ? 481 TYR A C 1 ATOM 3422 O O . TYR A 1 428 ? -41.193 42.403 11.661 1.00 24.92 ? 481 TYR A O 1 ATOM 3423 C CB . TYR A 1 428 ? -40.239 40.902 14.437 1.00 19.40 ? 481 TYR A CB 1 ATOM 3424 C CG . TYR A 1 428 ? -41.644 41.364 14.731 1.00 19.18 ? 481 TYR A CG 1 ATOM 3425 C CD1 . TYR A 1 428 ? -42.744 40.664 14.249 1.00 20.74 ? 481 TYR A CD1 1 ATOM 3426 C CD2 . TYR A 1 428 ? -41.869 42.510 15.468 1.00 18.89 ? 481 TYR A CD2 1 ATOM 3427 C CE1 . TYR A 1 428 ? -44.036 41.097 14.499 1.00 21.72 ? 481 TYR A CE1 1 ATOM 3428 C CE2 . TYR A 1 428 ? -43.145 42.945 15.740 1.00 21.98 ? 481 TYR A CE2 1 ATOM 3429 C CZ . TYR A 1 428 ? -44.231 42.238 15.252 1.00 24.97 ? 481 TYR A CZ 1 ATOM 3430 O OH . TYR A 1 428 ? -45.516 42.679 15.522 1.00 29.94 ? 481 TYR A OH 1 ATOM 3431 N N . PRO A 1 429 ? -40.450 40.313 11.429 1.00 20.59 ? 482 PRO A N 1 ATOM 3432 C CA . PRO A 1 429 ? -41.369 39.999 10.332 1.00 24.57 ? 482 PRO A CA 1 ATOM 3433 C C . PRO A 1 429 ? -42.696 39.447 10.842 1.00 28.14 ? 482 PRO A C 1 ATOM 3434 O O . PRO A 1 429 ? -42.738 38.378 11.451 1.00 29.15 ? 482 PRO A O 1 ATOM 3435 C CB . PRO A 1 429 ? -40.617 38.930 9.535 1.00 20.64 ? 482 PRO A CB 1 ATOM 3436 C CG . PRO A 1 429 ? -39.667 38.281 10.538 1.00 21.60 ? 482 PRO A CG 1 ATOM 3437 C CD . PRO A 1 429 ? -39.543 39.196 11.728 1.00 20.87 ? 482 PRO A CD 1 ATOM 3438 N N . ASP A 1 430 ? -43.772 40.171 10.567 1.00 33.38 ? 483 ASP A N 1 ATOM 3439 C CA . ASP A 1 430 ? -45.106 39.778 11.011 1.00 36.24 ? 483 ASP A CA 1 ATOM 3440 C C . ASP A 1 430 ? -45.412 38.292 10.798 1.00 34.70 ? 483 ASP A C 1 ATOM 3441 O O . ASP A 1 430 ? -46.132 37.684 11.578 1.00 34.72 ? 483 ASP A O 1 ATOM 3442 C CB . ASP A 1 430 ? -46.154 40.632 10.302 1.00 38.27 ? 483 ASP A CB 1 ATOM 3443 C CG . ASP A 1 430 ? -46.901 41.529 11.259 1.00 43.24 ? 483 ASP A CG 1 ATOM 3444 O OD1 . ASP A 1 430 ? -47.991 41.120 11.720 1.00 45.49 ? 483 ASP A OD1 1 ATOM 3445 O OD2 . ASP A 1 430 ? -46.472 42.652 11.620 1.00 46.45 ? 483 ASP A OD2 1 ATOM 3446 N N . ASP A 1 431 ? -44.865 37.707 9.742 1.00 35.75 ? 484 ASP A N 1 ATOM 3447 C CA . ASP A 1 431 ? -45.044 36.280 9.500 1.00 36.98 ? 484 ASP A CA 1 ATOM 3448 C C . ASP A 1 431 ? -44.906 35.482 10.787 1.00 33.75 ? 484 ASP A C 1 ATOM 3449 O O . ASP A 1 431 ? -45.702 34.579 11.048 1.00 31.18 ? 484 ASP A O 1 ATOM 3450 C CB . ASP A 1 431 ? -44.030 35.772 8.476 1.00 38.48 ? 484 ASP A CB 1 ATOM 3451 C CG . ASP A 1 431 ? -44.636 35.616 7.103 1.00 41.92 ? 484 ASP A CG 1 ATOM 3452 O OD1 . ASP A 1 431 ? -43.964 35.070 6.200 1.00 44.38 ? 484 ASP A OD1 1 ATOM 3453 O OD2 . ASP A 1 431 ? -45.784 36.019 6.835 1.00 42.60 ? 484 ASP A OD2 1 ATOM 3454 N N . ILE A 1 432 ? -43.881 35.787 11.580 1.00 30.28 ? 485 ILE A N 1 ATOM 3455 C CA . ILE A 1 432 ? -43.471 34.854 12.630 1.00 29.10 ? 485 ILE A CA 1 ATOM 3456 C C . ILE A 1 432 ? -44.502 34.882 13.751 1.00 26.13 ? 485 ILE A C 1 ATOM 3457 O O . ILE A 1 432 ? -44.497 34.032 14.628 1.00 25.66 ? 485 ILE A O 1 ATOM 3458 C CB . ILE A 1 432 ? -42.059 35.175 13.179 1.00 27.35 ? 485 ILE A CB 1 ATOM 3459 C CG1 . ILE A 1 432 ? -42.060 36.507 13.923 1.00 26.82 ? 485 ILE A CG1 1 ATOM 3460 C CG2 . ILE A 1 432 ? -41.041 35.207 12.051 1.00 28.04 ? 485 ILE A CG2 1 ATOM 3461 C CD1 . ILE A 1 432 ? -40.784 36.759 14.699 1.00 28.62 ? 485 ILE A CD1 1 ATOM 3462 N N . VAL A 1 433 ? -45.396 35.856 13.712 1.00 26.25 ? 486 VAL A N 1 ATOM 3463 C CA . VAL A 1 433 ? -46.521 35.850 14.635 1.00 29.50 ? 486 VAL A CA 1 ATOM 3464 C C . VAL A 1 433 ? -47.825 35.371 13.998 1.00 27.80 ? 486 VAL A C 1 ATOM 3465 O O . VAL A 1 433 ? -48.602 34.677 14.642 1.00 29.13 ? 486 VAL A O 1 ATOM 3466 C CB . VAL A 1 433 ? -46.746 37.241 15.264 1.00 30.52 ? 486 VAL A CB 1 ATOM 3467 C CG1 . VAL A 1 433 ? -47.982 37.230 16.149 1.00 31.29 ? 486 VAL A CG1 1 ATOM 3468 C CG2 . VAL A 1 433 ? -45.532 37.661 16.060 1.00 31.85 ? 486 VAL A CG2 1 ATOM 3469 N N . SER A 1 434 ? -48.076 35.748 12.749 1.00 28.71 ? 487 SER A N 1 ATOM 3470 C CA . SER A 1 434 ? -49.414 35.599 12.173 1.00 29.56 ? 487 SER A CA 1 ATOM 3471 C C . SER A 1 434 ? -49.555 34.274 11.422 1.00 30.29 ? 487 SER A C 1 ATOM 3472 O O . SER A 1 434 ? -50.664 33.792 11.182 1.00 33.65 ? 487 SER A O 1 ATOM 3473 C CB . SER A 1 434 ? -49.718 36.752 11.225 1.00 30.46 ? 487 SER A CB 1 ATOM 3474 O OG . SER A 1 434 ? -48.797 36.764 10.144 1.00 32.96 ? 487 SER A OG 1 ATOM 3475 N N . ASN A 1 435 ? -48.427 33.689 11.048 1.00 28.71 ? 488 ASN A N 1 ATOM 3476 C CA . ASN A 1 435 ? -48.435 32.539 10.170 1.00 25.82 ? 488 ASN A CA 1 ATOM 3477 C C . ASN A 1 435 ? -47.811 31.309 10.822 1.00 26.07 ? 488 ASN A C 1 ATOM 3478 O O . ASN A 1 435 ? -46.626 31.043 10.665 1.00 27.25 ? 488 ASN A O 1 ATOM 3479 C CB . ASN A 1 435 ? -47.715 32.871 8.872 1.00 26.81 ? 488 ASN A CB 1 ATOM 3480 C CG . ASN A 1 435 ? -47.994 31.864 7.793 1.00 25.74 ? 488 ASN A CG 1 ATOM 3481 O OD1 . ASN A 1 435 ? -48.360 30.732 8.081 1.00 28.72 ? 488 ASN A OD1 1 ATOM 3482 N ND2 . ASN A 1 435 ? -47.825 32.266 6.542 1.00 25.90 ? 488 ASN A ND2 1 ATOM 3483 N N . ASP A 1 436 ? -48.625 30.557 11.554 1.00 26.00 ? 489 ASP A N 1 ATOM 3484 C CA . ASP A 1 436 ? -48.127 29.477 12.370 1.00 27.30 ? 489 ASP A CA 1 ATOM 3485 C C . ASP A 1 436 ? -47.502 28.403 11.477 1.00 30.47 ? 489 ASP A C 1 ATOM 3486 O O . ASP A 1 436 ? -46.364 28.002 11.683 1.00 30.70 ? 489 ASP A O 1 ATOM 3487 C CB . ASP A 1 436 ? -49.269 28.896 13.203 1.00 29.12 ? 489 ASP A CB 1 ATOM 3488 C CG . ASP A 1 436 ? -49.584 29.735 14.429 1.00 28.26 ? 489 ASP A CG 1 ATOM 3489 O OD1 . ASP A 1 436 ? -48.890 30.747 14.657 1.00 27.59 ? 489 ASP A OD1 1 ATOM 3490 O OD2 . ASP A 1 436 ? -50.506 29.457 15.221 1.00 28.09 ? 489 ASP A OD2 1 ATOM 3491 N N . ASN A 1 437 ? -48.248 27.962 10.468 1.00 33.06 ? 490 ASN A N 1 ATOM 3492 C CA . ASN A 1 437 ? -47.752 26.974 9.507 1.00 32.46 ? 490 ASN A CA 1 ATOM 3493 C C . ASN A 1 437 ? -46.322 27.252 9.073 1.00 30.86 ? 490 ASN A C 1 ATOM 3494 O O . ASN A 1 437 ? -45.466 26.372 9.091 1.00 32.21 ? 490 ASN A O 1 ATOM 3495 C CB . ASN A 1 437 ? -48.635 26.965 8.259 1.00 33.54 ? 490 ASN A CB 1 ATOM 3496 C CG . ASN A 1 437 ? -49.761 25.977 8.351 1.00 34.59 ? 490 ASN A CG 1 ATOM 3497 O OD1 . ASN A 1 437 ? -50.780 26.130 7.683 1.00 37.80 ? 490 ASN A OD1 1 ATOM 3498 N ND2 . ASN A 1 437 ? -49.596 24.961 9.186 1.00 34.55 ? 490 ASN A ND2 1 ATOM 3499 N N . LYS A 1 438 ? -46.072 28.479 8.647 1.00 30.54 ? 491 LYS A N 1 ATOM 3500 C CA . LYS A 1 438 ? -44.780 28.819 8.085 1.00 29.73 ? 491 LYS A CA 1 ATOM 3501 C C . LYS A 1 438 ? -43.667 28.679 9.120 1.00 30.76 ? 491 LYS A C 1 ATOM 3502 O O . LYS A 1 438 ? -42.518 28.387 8.770 1.00 30.27 ? 491 LYS A O 1 ATOM 3503 C CB . LYS A 1 438 ? -44.809 30.237 7.548 1.00 31.01 ? 491 LYS A CB 1 ATOM 3504 C CG . LYS A 1 438 ? -43.440 30.806 7.268 1.00 32.18 ? 491 LYS A CG 1 ATOM 3505 C CD . LYS A 1 438 ? -43.546 32.068 6.445 1.00 31.88 ? 491 LYS A CD 1 ATOM 3506 C CE . LYS A 1 438 ? -42.202 32.440 5.845 1.00 32.09 ? 491 LYS A CE 1 ATOM 3507 N NZ . LYS A 1 438 ? -42.252 33.814 5.297 1.00 33.37 ? 491 LYS A NZ 1 ATOM 3508 N N . LEU A 1 439 ? -43.998 28.902 10.391 1.00 30.19 ? 492 LEU A N 1 ATOM 3509 C CA . LEU A 1 439 ? -42.983 28.880 11.437 1.00 27.31 ? 492 LEU A CA 1 ATOM 3510 C C . LEU A 1 439 ? -42.748 27.443 11.837 1.00 25.51 ? 492 LEU A C 1 ATOM 3511 O O . LEU A 1 439 ? -41.613 27.007 11.952 1.00 25.38 ? 492 LEU A O 1 ATOM 3512 C CB . LEU A 1 439 ? -43.397 29.722 12.648 1.00 27.96 ? 492 LEU A CB 1 ATOM 3513 C CG . LEU A 1 439 ? -42.314 29.940 13.716 1.00 27.41 ? 492 LEU A CG 1 ATOM 3514 C CD1 . LEU A 1 439 ? -41.963 28.637 14.435 1.00 27.99 ? 492 LEU A CD1 1 ATOM 3515 C CD2 . LEU A 1 439 ? -41.066 30.559 13.100 1.00 26.42 ? 492 LEU A CD2 1 ATOM 3516 N N . ASN A 1 440 ? -43.825 26.688 12.007 1.00 26.92 ? 493 ASN A N 1 ATOM 3517 C CA . ASN A 1 440 ? -43.689 25.260 12.220 1.00 27.41 ? 493 ASN A CA 1 ATOM 3518 C C . ASN A 1 440 ? -42.890 24.606 11.085 1.00 29.19 ? 493 ASN A C 1 ATOM 3519 O O . ASN A 1 440 ? -42.038 23.755 11.331 1.00 29.28 ? 493 ASN A O 1 ATOM 3520 C CB . ASN A 1 440 ? -45.056 24.609 12.389 1.00 28.57 ? 493 ASN A CB 1 ATOM 3521 C CG . ASN A 1 440 ? -45.722 24.964 13.720 1.00 29.76 ? 493 ASN A CG 1 ATOM 3522 O OD1 . ASN A 1 440 ? -45.064 25.101 14.750 1.00 28.72 ? 493 ASN A OD1 1 ATOM 3523 N ND2 . ASN A 1 440 ? -47.040 25.111 13.694 1.00 32.47 ? 493 ASN A ND2 1 ATOM 3524 N N . ASN A 1 441 ? -43.129 25.032 9.849 1.00 30.40 ? 494 ASN A N 1 ATOM 3525 C CA . ASN A 1 441 ? -42.527 24.365 8.692 1.00 32.02 ? 494 ASN A CA 1 ATOM 3526 C C . ASN A 1 441 ? -41.039 24.648 8.502 1.00 33.37 ? 494 ASN A C 1 ATOM 3527 O O . ASN A 1 441 ? -40.321 23.853 7.887 1.00 34.62 ? 494 ASN A O 1 ATOM 3528 C CB . ASN A 1 441 ? -43.289 24.727 7.414 1.00 32.04 ? 494 ASN A CB 1 ATOM 3529 C CG . ASN A 1 441 ? -44.529 23.879 7.228 1.00 30.62 ? 494 ASN A CG 1 ATOM 3530 O OD1 . ASN A 1 441 ? -44.661 22.825 7.846 1.00 30.55 ? 494 ASN A OD1 1 ATOM 3531 N ND2 . ASN A 1 441 ? -45.448 24.337 6.386 1.00 31.81 ? 494 ASN A ND2 1 ATOM 3532 N N . GLU A 1 442 ? -40.565 25.773 9.025 1.00 33.02 ? 495 GLU A N 1 ATOM 3533 C CA . GLU A 1 442 ? -39.133 26.049 9.013 1.00 31.93 ? 495 GLU A CA 1 ATOM 3534 C C . GLU A 1 442 ? -38.376 25.037 9.874 1.00 29.74 ? 495 GLU A C 1 ATOM 3535 O O . GLU A 1 442 ? -37.195 24.774 9.652 1.00 30.07 ? 495 GLU A O 1 ATOM 3536 C CB . GLU A 1 442 ? -38.857 27.466 9.506 1.00 32.64 ? 495 GLU A CB 1 ATOM 3537 C CG . GLU A 1 442 ? -37.427 27.928 9.306 1.00 31.81 ? 495 GLU A CG 1 ATOM 3538 C CD . GLU A 1 442 ? -37.153 29.275 9.954 1.00 32.79 ? 495 GLU A CD 1 ATOM 3539 O OE1 . GLU A 1 442 ? -38.118 30.036 10.208 1.00 29.41 ? 495 GLU A OE1 1 ATOM 3540 O OE2 . GLU A 1 442 ? -35.963 29.569 10.213 1.00 34.33 ? 495 GLU A OE2 1 ATOM 3541 N N . TYR A 1 443 ? -39.055 24.466 10.859 1.00 28.76 ? 496 TYR A N 1 ATOM 3542 C CA . TYR A 1 443 ? -38.394 23.549 11.787 1.00 29.80 ? 496 TYR A CA 1 ATOM 3543 C C . TYR A 1 443 ? -38.942 22.130 11.696 1.00 28.04 ? 496 TYR A C 1 ATOM 3544 O O . TYR A 1 443 ? -38.646 21.287 12.549 1.00 29.87 ? 496 TYR A O 1 ATOM 3545 C CB . TYR A 1 443 ? -38.548 24.062 13.218 1.00 28.66 ? 496 TYR A CB 1 ATOM 3546 C CG . TYR A 1 443 ? -38.074 25.470 13.377 1.00 27.67 ? 496 TYR A CG 1 ATOM 3547 C CD1 . TYR A 1 443 ? -36.738 25.786 13.219 1.00 26.58 ? 496 TYR A CD1 1 ATOM 3548 C CD2 . TYR A 1 443 ? -38.969 26.497 13.651 1.00 27.56 ? 496 TYR A CD2 1 ATOM 3549 C CE1 . TYR A 1 443 ? -36.305 27.083 13.345 1.00 28.72 ? 496 TYR A CE1 1 ATOM 3550 C CE2 . TYR A 1 443 ? -38.542 27.790 13.787 1.00 27.00 ? 496 TYR A CE2 1 ATOM 3551 C CZ . TYR A 1 443 ? -37.212 28.081 13.638 1.00 26.70 ? 496 TYR A CZ 1 ATOM 3552 O OH . TYR A 1 443 ? -36.781 29.375 13.778 1.00 28.77 ? 496 TYR A OH 1 ATOM 3553 N N . LEU A 1 444 ? -39.753 21.877 10.674 1.00 25.32 ? 497 LEU A N 1 ATOM 3554 C CA . LEU A 1 444 ? -40.352 20.564 10.481 1.00 27.12 ? 497 LEU A CA 1 ATOM 3555 C C . LEU A 1 444 ? -39.315 19.470 10.627 1.00 25.78 ? 497 LEU A C 1 ATOM 3556 O O . LEU A 1 444 ? -39.529 18.491 11.313 1.00 27.74 ? 497 LEU A O 1 ATOM 3557 C CB . LEU A 1 444 ? -40.964 20.464 9.090 1.00 27.95 ? 497 LEU A CB 1 ATOM 3558 C CG . LEU A 1 444 ? -42.433 20.065 9.025 1.00 28.49 ? 497 LEU A CG 1 ATOM 3559 C CD1 . LEU A 1 444 ? -42.676 19.234 7.784 1.00 28.31 ? 497 LEU A CD1 1 ATOM 3560 C CD2 . LEU A 1 444 ? -42.861 19.324 10.274 1.00 29.85 ? 497 LEU A CD2 1 ATOM 3561 N N . GLU A 1 445 ? -38.193 19.630 9.955 1.00 26.98 ? 498 GLU A N 1 ATOM 3562 C CA . GLU A 1 445 ? -37.298 18.512 9.761 1.00 32.20 ? 498 GLU A CA 1 ATOM 3563 C C . GLU A 1 445 ? -36.535 18.259 11.055 1.00 32.94 ? 498 GLU A C 1 ATOM 3564 O O . GLU A 1 445 ? -35.813 17.274 11.180 1.00 38.00 ? 498 GLU A O 1 ATOM 3565 C CB . GLU A 1 445 ? -36.350 18.781 8.594 1.00 33.92 ? 498 GLU A CB 1 ATOM 3566 C CG . GLU A 1 445 ? -36.376 17.699 7.523 1.00 37.92 ? 498 GLU A CG 1 ATOM 3567 C CD . GLU A 1 445 ? -36.465 18.237 6.096 1.00 37.32 ? 498 GLU A CD 1 ATOM 3568 O OE1 . GLU A 1 445 ? -36.512 19.471 5.898 1.00 38.93 ? 498 GLU A OE1 1 ATOM 3569 O OE2 . GLU A 1 445 ? -36.481 17.412 5.166 1.00 35.38 ? 498 GLU A OE2 1 ATOM 3570 N N . LEU A 1 446 ? -36.714 19.139 12.031 1.00 31.34 ? 499 LEU A N 1 ATOM 3571 C CA . LEU A 1 446 ? -36.030 18.973 13.305 1.00 30.74 ? 499 LEU A CA 1 ATOM 3572 C C . LEU A 1 446 ? -36.882 18.220 14.313 1.00 28.96 ? 499 LEU A C 1 ATOM 3573 O O . LEU A 1 446 ? -38.095 18.393 14.370 1.00 25.51 ? 499 LEU A O 1 ATOM 3574 C CB . LEU A 1 446 ? -35.626 20.327 13.863 1.00 31.97 ? 499 LEU A CB 1 ATOM 3575 C CG . LEU A 1 446 ? -34.608 21.029 12.970 1.00 32.67 ? 499 LEU A CG 1 ATOM 3576 C CD1 . LEU A 1 446 ? -34.521 22.509 13.313 1.00 33.33 ? 499 LEU A CD1 1 ATOM 3577 C CD2 . LEU A 1 446 ? -33.253 20.354 13.104 1.00 32.33 ? 499 LEU A CD2 1 ATOM 3578 N N . ASN A 1 447 ? -36.228 17.372 15.098 1.00 31.63 ? 500 ASN A N 1 ATOM 3579 C CA . ASN A 1 447 ? -36.885 16.636 16.165 1.00 34.36 ? 500 ASN A CA 1 ATOM 3580 C C . ASN A 1 447 ? -35.913 16.397 17.309 1.00 32.39 ? 500 ASN A C 1 ATOM 3581 O O . ASN A 1 447 ? -34.953 15.636 17.171 1.00 33.49 ? 500 ASN A O 1 ATOM 3582 C CB . ASN A 1 447 ? -37.414 15.303 15.628 1.00 40.28 ? 500 ASN A CB 1 ATOM 3583 C CG . ASN A 1 447 ? -38.231 14.538 16.655 1.00 45.26 ? 500 ASN A CG 1 ATOM 3584 O OD1 . ASN A 1 447 ? -37.827 13.462 17.100 1.00 50.05 ? 500 ASN A OD1 1 ATOM 3585 N ND2 . ASN A 1 447 ? -39.395 15.081 17.025 1.00 46.99 ? 500 ASN A ND2 1 ATOM 3586 N N . TYR A 1 448 ? -36.144 17.068 18.431 1.00 30.98 ? 501 TYR A N 1 ATOM 3587 C CA . TYR A 1 448 ? -35.158 17.135 19.491 1.00 28.04 ? 501 TYR A CA 1 ATOM 3588 C C . TYR A 1 448 ? -35.509 16.156 20.589 1.00 31.75 ? 501 TYR A C 1 ATOM 3589 O O . TYR A 1 448 ? -36.681 15.923 20.860 1.00 34.71 ? 501 TYR A O 1 ATOM 3590 C CB . TYR A 1 448 ? -35.098 18.538 20.078 1.00 25.49 ? 501 TYR A CB 1 ATOM 3591 C CG . TYR A 1 448 ? -34.558 19.604 19.149 1.00 23.41 ? 501 TYR A CG 1 ATOM 3592 C CD1 . TYR A 1 448 ? -33.443 19.381 18.334 1.00 19.92 ? 501 TYR A CD1 1 ATOM 3593 C CD2 . TYR A 1 448 ? -35.149 20.853 19.120 1.00 20.65 ? 501 TYR A CD2 1 ATOM 3594 C CE1 . TYR A 1 448 ? -32.965 20.386 17.507 1.00 18.49 ? 501 TYR A CE1 1 ATOM 3595 C CE2 . TYR A 1 448 ? -34.690 21.838 18.313 1.00 20.48 ? 501 TYR A CE2 1 ATOM 3596 C CZ . TYR A 1 448 ? -33.621 21.609 17.505 1.00 19.22 ? 501 TYR A CZ 1 ATOM 3597 O OH . TYR A 1 448 ? -33.217 22.647 16.722 1.00 17.49 ? 501 TYR A OH 1 ATOM 3598 N N . LYS A 1 449 ? -34.495 15.590 21.234 1.00 35.37 ? 502 LYS A N 1 ATOM 3599 C CA . LYS A 1 449 ? -34.720 14.776 22.425 1.00 37.46 ? 502 LYS A CA 1 ATOM 3600 C C . LYS A 1 449 ? -34.145 15.429 23.684 1.00 35.81 ? 502 LYS A C 1 ATOM 3601 O O . LYS A 1 449 ? -32.993 15.860 23.710 1.00 35.23 ? 502 LYS A O 1 ATOM 3602 C CB . LYS A 1 449 ? -34.113 13.384 22.237 1.00 40.03 ? 502 LYS A CB 1 ATOM 3603 C CG . LYS A 1 449 ? -34.726 12.595 21.099 1.00 41.75 ? 502 LYS A CG 1 ATOM 3604 C CD . LYS A 1 449 ? -34.329 11.129 21.142 1.00 43.49 ? 502 LYS A CD 1 ATOM 3605 C CE . LYS A 1 449 ? -32.840 10.924 20.872 1.00 45.37 ? 502 LYS A CE 1 ATOM 3606 N NZ . LYS A 1 449 ? -32.526 9.498 20.503 1.00 46.12 ? 502 LYS A NZ 1 ATOM 3607 N N . GLU A 1 450 ? -34.960 15.493 24.728 1.00 33.31 ? 503 GLU A N 1 ATOM 3608 C CA . GLU A 1 450 ? -34.730 16.425 25.813 1.00 32.20 ? 503 GLU A CA 1 ATOM 3609 C C . GLU A 1 450 ? -33.535 15.990 26.650 1.00 28.94 ? 503 GLU A C 1 ATOM 3610 O O . GLU A 1 450 ? -33.001 16.776 27.425 1.00 28.57 ? 503 GLU A O 1 ATOM 3611 C CB . GLU A 1 450 ? -35.971 16.521 26.696 1.00 34.08 ? 503 GLU A CB 1 ATOM 3612 C CG . GLU A 1 450 ? -37.169 17.137 25.998 1.00 34.78 ? 503 GLU A CG 1 ATOM 3613 C CD . GLU A 1 450 ? -38.148 17.746 26.973 1.00 35.32 ? 503 GLU A CD 1 ATOM 3614 O OE1 . GLU A 1 450 ? -39.348 17.830 26.646 1.00 37.78 ? 503 GLU A OE1 1 ATOM 3615 O OE2 . GLU A 1 450 ? -37.714 18.140 28.071 1.00 36.27 ? 503 GLU A OE2 1 ATOM 3616 N N . ASP A 1 451 ? -33.126 14.737 26.486 1.00 25.66 ? 504 ASP A N 1 ATOM 3617 C CA . ASP A 1 451 ? -32.038 14.171 27.264 1.00 27.23 ? 504 ASP A CA 1 ATOM 3618 C C . ASP A 1 451 ? -30.794 13.959 26.413 1.00 27.99 ? 504 ASP A C 1 ATOM 3619 O O . ASP A 1 451 ? -29.845 13.315 26.842 1.00 26.08 ? 504 ASP A O 1 ATOM 3620 C CB . ASP A 1 451 ? -32.473 12.838 27.880 1.00 31.90 ? 504 ASP A CB 1 ATOM 3621 C CG . ASP A 1 451 ? -32.859 11.809 26.838 1.00 35.48 ? 504 ASP A CG 1 ATOM 3622 O OD1 . ASP A 1 451 ? -32.582 10.606 27.052 1.00 41.74 ? 504 ASP A OD1 1 ATOM 3623 O OD2 . ASP A 1 451 ? -33.439 12.103 25.773 1.00 37.41 ? 504 ASP A OD2 1 ATOM 3624 N N . GLU A 1 452 ? -30.803 14.497 25.199 1.00 27.78 ? 505 GLU A N 1 ATOM 3625 C CA . GLU A 1 452 ? -29.698 14.303 24.281 1.00 28.81 ? 505 GLU A CA 1 ATOM 3626 C C . GLU A 1 452 ? -29.284 15.621 23.653 1.00 26.41 ? 505 GLU A C 1 ATOM 3627 O O . GLU A 1 452 ? -29.424 15.801 22.445 1.00 27.69 ? 505 GLU A O 1 ATOM 3628 C CB . GLU A 1 452 ? -30.093 13.309 23.183 1.00 31.83 ? 505 GLU A CB 1 ATOM 3629 C CG . GLU A 1 452 ? -30.354 11.906 23.699 1.00 34.04 ? 505 GLU A CG 1 ATOM 3630 C CD . GLU A 1 452 ? -29.184 11.351 24.491 1.00 36.22 ? 505 GLU A CD 1 ATOM 3631 O OE1 . GLU A 1 452 ? -28.078 11.925 24.389 1.00 39.83 ? 505 GLU A OE1 1 ATOM 3632 O OE2 . GLU A 1 452 ? -29.362 10.340 25.210 1.00 37.84 ? 505 GLU A OE2 1 ATOM 3633 N N . TYR A 1 453 ? -28.779 16.541 24.472 1.00 23.93 ? 506 TYR A N 1 ATOM 3634 C CA . TYR A 1 453 ? -28.341 17.842 23.979 1.00 22.41 ? 506 TYR A CA 1 ATOM 3635 C C . TYR A 1 453 ? -27.313 17.693 22.848 1.00 22.43 ? 506 TYR A C 1 ATOM 3636 O O . TYR A 1 453 ? -27.395 18.393 21.845 1.00 21.14 ? 506 TYR A O 1 ATOM 3637 C CB . TYR A 1 453 ? -27.768 18.699 25.115 1.00 20.84 ? 506 TYR A CB 1 ATOM 3638 C CG . TYR A 1 453 ? -27.195 20.023 24.645 1.00 20.50 ? 506 TYR A CG 1 ATOM 3639 C CD1 . TYR A 1 453 ? -25.834 20.299 24.754 1.00 20.56 ? 506 TYR A CD1 1 ATOM 3640 C CD2 . TYR A 1 453 ? -28.007 20.986 24.083 1.00 18.52 ? 506 TYR A CD2 1 ATOM 3641 C CE1 . TYR A 1 453 ? -25.318 21.502 24.323 1.00 21.24 ? 506 TYR A CE1 1 ATOM 3642 C CE2 . TYR A 1 453 ? -27.496 22.194 23.660 1.00 18.41 ? 506 TYR A CE2 1 ATOM 3643 C CZ . TYR A 1 453 ? -26.160 22.444 23.775 1.00 18.38 ? 506 TYR A CZ 1 ATOM 3644 O OH . TYR A 1 453 ? -25.662 23.640 23.335 1.00 17.75 ? 506 TYR A OH 1 ATOM 3645 N N . PHE A 1 454 ? -26.365 16.770 22.999 1.00 24.33 ? 507 PHE A N 1 ATOM 3646 C CA . PHE A 1 454 ? -25.280 16.629 22.016 1.00 25.74 ? 507 PHE A CA 1 ATOM 3647 C C . PHE A 1 454 ? -25.800 16.104 20.675 1.00 26.17 ? 507 PHE A C 1 ATOM 3648 O O . PHE A 1 454 ? -25.466 16.632 19.618 1.00 25.89 ? 507 PHE A O 1 ATOM 3649 C CB . PHE A 1 454 ? -24.151 15.726 22.546 1.00 22.65 ? 507 PHE A CB 1 ATOM 3650 C CG . PHE A 1 454 ? -22.850 15.861 21.787 1.00 22.18 ? 507 PHE A CG 1 ATOM 3651 C CD1 . PHE A 1 454 ? -22.594 15.081 20.670 1.00 22.24 ? 507 PHE A CD1 1 ATOM 3652 C CD2 . PHE A 1 454 ? -21.883 16.775 22.185 1.00 23.09 ? 507 PHE A CD2 1 ATOM 3653 C CE1 . PHE A 1 454 ? -21.397 15.201 19.974 1.00 18.87 ? 507 PHE A CE1 1 ATOM 3654 C CE2 . PHE A 1 454 ? -20.674 16.896 21.484 1.00 19.29 ? 507 PHE A CE2 1 ATOM 3655 C CZ . PHE A 1 454 ? -20.440 16.108 20.385 1.00 17.69 ? 507 PHE A CZ 1 ATOM 3656 N N . GLU A 1 455 ? -26.646 15.089 20.715 1.00 28.08 ? 508 GLU A N 1 ATOM 3657 C CA . GLU A 1 455 ? -27.393 14.710 19.521 1.00 29.55 ? 508 GLU A CA 1 ATOM 3658 C C . GLU A 1 455 ? -28.066 15.931 18.898 1.00 29.03 ? 508 GLU A C 1 ATOM 3659 O O . GLU A 1 455 ? -28.023 16.118 17.682 1.00 25.58 ? 508 GLU A O 1 ATOM 3660 C CB . GLU A 1 455 ? -28.440 13.647 19.850 1.00 32.03 ? 508 GLU A CB 1 ATOM 3661 C CG . GLU A 1 455 ? -27.854 12.274 20.116 1.00 35.18 ? 508 GLU A CG 1 ATOM 3662 C CD . GLU A 1 455 ? -26.893 12.261 21.291 1.00 39.85 ? 508 GLU A CD 1 ATOM 3663 O OE1 . GLU A 1 455 ? -26.998 13.144 22.179 1.00 44.89 ? 508 GLU A OE1 1 ATOM 3664 O OE2 . GLU A 1 455 ? -26.031 11.356 21.334 1.00 43.41 ? 508 GLU A OE2 1 ATOM 3665 N N . ASN A 1 456 ? -28.696 16.756 19.730 1.00 28.26 ? 509 ASN A N 1 ATOM 3666 C CA . ASN A 1 456 ? -29.500 17.852 19.217 1.00 26.81 ? 509 ASN A CA 1 ATOM 3667 C C . ASN A 1 456 ? -28.618 18.802 18.428 1.00 29.29 ? 509 ASN A C 1 ATOM 3668 O O . ASN A 1 456 ? -28.960 19.200 17.317 1.00 33.26 ? 509 ASN A O 1 ATOM 3669 C CB . ASN A 1 456 ? -30.193 18.603 20.349 1.00 28.60 ? 509 ASN A CB 1 ATOM 3670 C CG . ASN A 1 456 ? -31.298 17.795 20.992 1.00 25.44 ? 509 ASN A CG 1 ATOM 3671 O OD1 . ASN A 1 456 ? -31.650 18.015 22.147 1.00 25.52 ? 509 ASN A OD1 1 ATOM 3672 N ND2 . ASN A 1 456 ? -31.840 16.852 20.253 1.00 21.74 ? 509 ASN A ND2 1 ATOM 3673 N N . ILE A 1 457 ? -27.461 19.156 18.987 1.00 26.80 ? 510 ILE A N 1 ATOM 3674 C CA . ILE A 1 457 ? -26.651 20.196 18.360 1.00 25.66 ? 510 ILE A CA 1 ATOM 3675 C C . ILE A 1 457 ? -25.918 19.653 17.137 1.00 23.86 ? 510 ILE A C 1 ATOM 3676 O O . ILE A 1 457 ? -25.749 20.353 16.146 1.00 19.79 ? 510 ILE A O 1 ATOM 3677 C CB . ILE A 1 457 ? -25.627 20.831 19.339 1.00 27.25 ? 510 ILE A CB 1 ATOM 3678 C CG1 . ILE A 1 457 ? -24.401 19.937 19.511 1.00 26.48 ? 510 ILE A CG1 1 ATOM 3679 C CG2 . ILE A 1 457 ? -26.254 21.135 20.690 1.00 27.92 ? 510 ILE A CG2 1 ATOM 3680 C CD1 . ILE A 1 457 ? -23.479 20.433 20.586 1.00 29.13 ? 510 ILE A CD1 1 ATOM 3681 N N . ILE A 1 458 ? -25.484 18.402 17.186 1.00 24.70 ? 511 ILE A N 1 ATOM 3682 C CA . ILE A 1 458 ? -25.100 17.743 15.952 1.00 26.16 ? 511 ILE A CA 1 ATOM 3683 C C . ILE A 1 458 ? -26.187 17.946 14.883 1.00 26.37 ? 511 ILE A C 1 ATOM 3684 O O . ILE A 1 458 ? -25.906 18.423 13.774 1.00 23.04 ? 511 ILE A O 1 ATOM 3685 C CB . ILE A 1 458 ? -24.810 16.253 16.174 1.00 28.00 ? 511 ILE A CB 1 ATOM 3686 C CG1 . ILE A 1 458 ? -23.687 16.085 17.191 1.00 26.76 ? 511 ILE A CG1 1 ATOM 3687 C CG2 . ILE A 1 458 ? -24.408 15.592 14.853 1.00 28.21 ? 511 ILE A CG2 1 ATOM 3688 C CD1 . ILE A 1 458 ? -22.438 16.812 16.794 1.00 26.67 ? 511 ILE A CD1 1 ATOM 3689 N N . GLN A 1 459 ? -27.427 17.606 15.217 1.00 25.90 ? 512 GLN A N 1 ATOM 3690 C CA . GLN A 1 459 ? -28.498 17.674 14.228 1.00 25.62 ? 512 GLN A CA 1 ATOM 3691 C C . GLN A 1 459 ? -28.641 19.078 13.654 1.00 26.26 ? 512 GLN A C 1 ATOM 3692 O O . GLN A 1 459 ? -28.792 19.234 12.446 1.00 27.21 ? 512 GLN A O 1 ATOM 3693 C CB . GLN A 1 459 ? -29.841 17.209 14.809 1.00 26.65 ? 512 GLN A CB 1 ATOM 3694 C CG . GLN A 1 459 ? -30.951 17.239 13.782 1.00 26.11 ? 512 GLN A CG 1 ATOM 3695 C CD . GLN A 1 459 ? -32.337 16.990 14.354 1.00 29.47 ? 512 GLN A CD 1 ATOM 3696 O OE1 . GLN A 1 459 ? -33.332 17.401 13.754 1.00 33.17 ? 512 GLN A OE1 1 ATOM 3697 N NE2 . GLN A 1 459 ? -32.413 16.309 15.491 1.00 28.89 ? 512 GLN A NE2 1 ATOM 3698 N N . ASN A 1 460 ? -28.594 20.102 14.506 1.00 27.36 ? 513 ASN A N 1 ATOM 3699 C CA . ASN A 1 460 ? -28.666 21.482 14.020 1.00 25.82 ? 513 ASN A CA 1 ATOM 3700 C C . ASN A 1 460 ? -27.524 21.819 13.044 1.00 26.94 ? 513 ASN A C 1 ATOM 3701 O O . ASN A 1 460 ? -27.734 22.531 12.065 1.00 28.88 ? 513 ASN A O 1 ATOM 3702 C CB . ASN A 1 460 ? -28.703 22.485 15.184 1.00 27.92 ? 513 ASN A CB 1 ATOM 3703 C CG . ASN A 1 460 ? -30.098 22.600 15.844 1.00 27.62 ? 513 ASN A CG 1 ATOM 3704 O OD1 . ASN A 1 460 ? -31.072 22.010 15.385 1.00 26.57 ? 513 ASN A OD1 1 ATOM 3705 N ND2 . ASN A 1 460 ? -30.175 23.354 16.935 1.00 28.49 ? 513 ASN A ND2 1 ATOM 3706 N N . LEU A 1 461 ? -26.318 21.304 13.273 1.00 27.91 ? 514 LEU A N 1 ATOM 3707 C CA . LEU A 1 461 ? -25.231 21.558 12.321 1.00 26.74 ? 514 LEU A CA 1 ATOM 3708 C C . LEU A 1 461 ? -25.556 20.954 10.947 1.00 27.67 ? 514 LEU A C 1 ATOM 3709 O O . LEU A 1 461 ? -25.369 21.617 9.929 1.00 21.43 ? 514 LEU A O 1 ATOM 3710 C CB . LEU A 1 461 ? -23.888 21.028 12.828 1.00 26.25 ? 514 LEU A CB 1 ATOM 3711 C CG . LEU A 1 461 ? -23.274 21.766 14.024 1.00 27.94 ? 514 LEU A CG 1 ATOM 3712 C CD1 . LEU A 1 461 ? -22.110 20.985 14.573 1.00 27.05 ? 514 LEU A CD1 1 ATOM 3713 C CD2 . LEU A 1 461 ? -22.839 23.172 13.658 1.00 27.26 ? 514 LEU A CD2 1 ATOM 3714 N N . LYS A 1 462 ? -26.043 19.707 10.938 1.00 28.54 ? 515 LYS A N 1 ATOM 3715 C CA . LYS A 1 462 ? -26.436 19.007 9.707 1.00 30.13 ? 515 LYS A CA 1 ATOM 3716 C C . LYS A 1 462 ? -27.545 19.744 8.968 1.00 31.56 ? 515 LYS A C 1 ATOM 3717 O O . LYS A 1 462 ? -27.459 20.012 7.768 1.00 32.13 ? 515 LYS A O 1 ATOM 3718 C CB . LYS A 1 462 ? -26.924 17.583 10.025 1.00 30.96 ? 515 LYS A CB 1 ATOM 3719 C CG . LYS A 1 462 ? -25.828 16.612 10.539 1.00 32.59 ? 515 LYS A CG 1 ATOM 3720 C CD . LYS A 1 462 ? -26.313 15.156 10.557 1.00 32.75 ? 515 LYS A CD 1 ATOM 3721 C CE . LYS A 1 462 ? -25.153 14.154 10.692 1.00 33.78 ? 515 LYS A CE 1 ATOM 3722 N NZ . LYS A 1 462 ? -25.416 13.118 11.744 1.00 31.28 ? 515 LYS A NZ 1 ATOM 3723 N N . PHE A 1 463 ? -28.602 20.056 9.694 1.00 32.09 ? 516 PHE A N 1 ATOM 3724 C CA . PHE A 1 463 ? -29.722 20.760 9.116 1.00 32.67 ? 516 PHE A CA 1 ATOM 3725 C C . PHE A 1 463 ? -29.268 22.074 8.491 1.00 31.56 ? 516 PHE A C 1 ATOM 3726 O O . PHE A 1 463 ? -29.613 22.385 7.362 1.00 29.74 ? 516 PHE A O 1 ATOM 3727 C CB . PHE A 1 463 ? -30.750 21.045 10.195 1.00 33.44 ? 516 PHE A CB 1 ATOM 3728 C CG . PHE A 1 463 ? -32.048 21.537 9.663 1.00 35.83 ? 516 PHE A CG 1 ATOM 3729 C CD1 . PHE A 1 463 ? -32.362 22.879 9.705 1.00 36.39 ? 516 PHE A CD1 1 ATOM 3730 C CD2 . PHE A 1 463 ? -32.961 20.653 9.113 1.00 38.78 ? 516 PHE A CD2 1 ATOM 3731 C CE1 . PHE A 1 463 ? -33.573 23.334 9.221 1.00 38.25 ? 516 PHE A CE1 1 ATOM 3732 C CE2 . PHE A 1 463 ? -34.173 21.105 8.620 1.00 40.11 ? 516 PHE A CE2 1 ATOM 3733 C CZ . PHE A 1 463 ? -34.477 22.447 8.677 1.00 39.30 ? 516 PHE A CZ 1 ATOM 3734 N N . SER A 1 464 ? -28.510 22.842 9.261 1.00 30.88 ? 517 SER A N 1 ATOM 3735 C CA . SER A 1 464 ? -27.999 24.133 8.837 1.00 32.12 ? 517 SER A CA 1 ATOM 3736 C C . SER A 1 464 ? -27.291 24.005 7.500 1.00 34.69 ? 517 SER A C 1 ATOM 3737 O O . SER A 1 464 ? -27.503 24.795 6.576 1.00 33.15 ? 517 SER A O 1 ATOM 3738 C CB . SER A 1 464 ? -27.006 24.637 9.886 1.00 31.24 ? 517 SER A CB 1 ATOM 3739 O OG . SER A 1 464 ? -26.887 26.041 9.865 1.00 31.93 ? 517 SER A OG 1 ATOM 3740 N N . GLN A 1 465 ? -26.428 23.005 7.412 1.00 36.16 ? 518 GLN A N 1 ATOM 3741 C CA . GLN A 1 465 ? -25.537 22.889 6.277 1.00 38.55 ? 518 GLN A CA 1 ATOM 3742 C C . GLN A 1 465 ? -26.265 22.315 5.065 1.00 37.18 ? 518 GLN A C 1 ATOM 3743 O O . GLN A 1 465 ? -26.074 22.779 3.947 1.00 35.48 ? 518 GLN A O 1 ATOM 3744 C CB . GLN A 1 465 ? -24.342 22.017 6.632 1.00 37.97 ? 518 GLN A CB 1 ATOM 3745 C CG . GLN A 1 465 ? -23.215 22.153 5.644 1.00 41.16 ? 518 GLN A CG 1 ATOM 3746 C CD . GLN A 1 465 ? -22.565 23.524 5.667 1.00 40.19 ? 518 GLN A CD 1 ATOM 3747 O OE1 . GLN A 1 465 ? -22.891 24.362 6.507 1.00 39.11 ? 518 GLN A OE1 1 ATOM 3748 N NE2 . GLN A 1 465 ? -21.640 23.752 4.741 1.00 41.42 ? 518 GLN A NE2 1 ATOM 3749 N N . SER A 1 466 ? -27.098 21.307 5.292 1.00 37.01 ? 519 SER A N 1 ATOM 3750 C CA . SER A 1 466 ? -28.055 20.863 4.279 1.00 37.26 ? 519 SER A CA 1 ATOM 3751 C C . SER A 1 466 ? -28.825 22.036 3.673 1.00 35.10 ? 519 SER A C 1 ATOM 3752 O O . SER A 1 466 ? -28.884 22.189 2.453 1.00 36.07 ? 519 SER A O 1 ATOM 3753 C CB . SER A 1 466 ? -29.031 19.854 4.878 1.00 38.15 ? 519 SER A CB 1 ATOM 3754 O OG . SER A 1 466 ? -28.772 18.550 4.387 1.00 40.80 ? 519 SER A OG 1 ATOM 3755 N N . LYS A 1 467 ? -29.404 22.868 4.527 1.00 29.75 ? 520 LYS A N 1 ATOM 3756 C CA . LYS A 1 467 ? -30.194 23.995 4.064 1.00 31.02 ? 520 LYS A CA 1 ATOM 3757 C C . LYS A 1 467 ? -29.422 24.830 3.059 1.00 31.65 ? 520 LYS A C 1 ATOM 3758 O O . LYS A 1 467 ? -29.918 25.123 1.969 1.00 31.14 ? 520 LYS A O 1 ATOM 3759 C CB . LYS A 1 467 ? -30.592 24.884 5.240 1.00 32.05 ? 520 LYS A CB 1 ATOM 3760 C CG . LYS A 1 467 ? -31.931 25.553 5.072 1.00 32.13 ? 520 LYS A CG 1 ATOM 3761 C CD . LYS A 1 467 ? -31.876 27.019 5.479 1.00 33.28 ? 520 LYS A CD 1 ATOM 3762 C CE . LYS A 1 467 ? -32.934 27.315 6.517 1.00 32.83 ? 520 LYS A CE 1 ATOM 3763 N NZ . LYS A 1 467 ? -33.334 26.062 7.201 1.00 31.94 ? 520 LYS A NZ 1 ATOM 3764 N N . GLN A 1 468 ? -28.211 25.224 3.447 1.00 31.51 ? 521 GLN A N 1 ATOM 3765 C CA . GLN A 1 468 ? -27.461 26.248 2.737 1.00 32.01 ? 521 GLN A CA 1 ATOM 3766 C C . GLN A 1 468 ? -27.098 25.735 1.352 1.00 31.19 ? 521 GLN A C 1 ATOM 3767 O O . GLN A 1 468 ? -27.284 26.436 0.362 1.00 30.32 ? 521 GLN A O 1 ATOM 3768 C CB . GLN A 1 468 ? -26.198 26.624 3.522 1.00 33.38 ? 521 GLN A CB 1 ATOM 3769 C CG . GLN A 1 468 ? -25.412 27.804 2.956 1.00 35.95 ? 521 GLN A CG 1 ATOM 3770 C CD . GLN A 1 468 ? -26.268 29.041 2.697 1.00 38.45 ? 521 GLN A CD 1 ATOM 3771 O OE1 . GLN A 1 468 ? -27.356 29.183 3.258 1.00 38.03 ? 521 GLN A OE1 1 ATOM 3772 N NE2 . GLN A 1 468 ? -25.763 29.950 1.856 1.00 41.22 ? 521 GLN A NE2 1 ATOM 3773 N N . LEU A 1 469 ? -26.593 24.506 1.286 1.00 32.31 ? 522 LEU A N 1 ATOM 3774 C CA . LEU A 1 469 ? -26.019 23.983 0.050 1.00 35.40 ? 522 LEU A CA 1 ATOM 3775 C C . LEU A 1 469 ? -27.086 23.783 -1.020 1.00 38.97 ? 522 LEU A C 1 ATOM 3776 O O . LEU A 1 469 ? -26.796 23.851 -2.214 1.00 40.58 ? 522 LEU A O 1 ATOM 3777 C CB . LEU A 1 469 ? -25.291 22.667 0.302 1.00 36.72 ? 522 LEU A CB 1 ATOM 3778 C CG . LEU A 1 469 ? -25.262 22.194 1.751 1.00 38.97 ? 522 LEU A CG 1 ATOM 3779 C CD1 . LEU A 1 469 ? -23.866 21.694 2.081 1.00 38.08 ? 522 LEU A CD1 1 ATOM 3780 C CD2 . LEU A 1 469 ? -25.703 23.316 2.691 1.00 40.65 ? 522 LEU A CD2 1 ATOM 3781 N N . LYS A 1 470 ? -28.319 23.534 -0.595 1.00 39.28 ? 523 LYS A N 1 ATOM 3782 C CA . LYS A 1 470 ? -29.393 23.273 -1.537 1.00 40.61 ? 523 LYS A CA 1 ATOM 3783 C C . LYS A 1 470 ? -29.902 24.567 -2.168 1.00 41.11 ? 523 LYS A C 1 ATOM 3784 O O . LYS A 1 470 ? -30.761 24.537 -3.052 1.00 43.68 ? 523 LYS A O 1 ATOM 3785 C CB . LYS A 1 470 ? -30.531 22.516 -0.853 1.00 41.28 ? 523 LYS A CB 1 ATOM 3786 C CG . LYS A 1 470 ? -31.705 23.373 -0.445 1.00 41.82 ? 523 LYS A CG 1 ATOM 3787 C CD . LYS A 1 470 ? -32.747 22.547 0.294 1.00 43.49 ? 523 LYS A CD 1 ATOM 3788 C CE . LYS A 1 470 ? -32.555 21.060 0.038 1.00 43.34 ? 523 LYS A CE 1 ATOM 3789 N NZ . LYS A 1 470 ? -31.162 20.745 -0.387 1.00 42.36 ? 523 LYS A NZ 1 ATOM 3790 N N . LYS A 1 471 ? -29.359 25.696 -1.729 1.00 37.38 ? 524 LYS A N 1 ATOM 3791 C CA . LYS A 1 471 ? -29.666 26.978 -2.351 1.00 37.97 ? 524 LYS A CA 1 ATOM 3792 C C . LYS A 1 471 ? -28.964 27.162 -3.702 1.00 36.79 ? 524 LYS A C 1 ATOM 3793 O O . LYS A 1 471 ? -29.248 28.112 -4.426 1.00 34.56 ? 524 LYS A O 1 ATOM 3794 C CB . LYS A 1 471 ? -29.279 28.131 -1.416 1.00 39.63 ? 524 LYS A CB 1 ATOM 3795 C CG . LYS A 1 471 ? -30.235 28.333 -0.239 1.00 40.50 ? 524 LYS A CG 1 ATOM 3796 C CD . LYS A 1 471 ? -29.562 29.051 0.925 1.00 41.47 ? 524 LYS A CD 1 ATOM 3797 C CE . LYS A 1 471 ? -30.535 29.969 1.658 1.00 42.70 ? 524 LYS A CE 1 ATOM 3798 N NZ . LYS A 1 471 ? -29.859 31.149 2.282 1.00 41.39 ? 524 LYS A NZ 1 ATOM 3799 N N . LEU A 1 472 ? -28.034 26.271 -4.029 1.00 37.50 ? 525 LEU A N 1 ATOM 3800 C CA . LEU A 1 472 ? -27.130 26.495 -5.156 1.00 37.00 ? 525 LEU A CA 1 ATOM 3801 C C . LEU A 1 472 ? -27.907 26.920 -6.396 1.00 37.37 ? 525 LEU A C 1 ATOM 3802 O O . LEU A 1 472 ? -27.609 27.951 -7.002 1.00 35.57 ? 525 LEU A O 1 ATOM 3803 C CB . LEU A 1 472 ? -26.318 25.232 -5.467 1.00 37.00 ? 525 LEU A CB 1 ATOM 3804 C CG . LEU A 1 472 ? -25.265 25.387 -6.570 1.00 34.45 ? 525 LEU A CG 1 ATOM 3805 C CD1 . LEU A 1 472 ? -24.314 26.513 -6.235 1.00 34.92 ? 525 LEU A CD1 1 ATOM 3806 C CD2 . LEU A 1 472 ? -24.495 24.113 -6.769 1.00 34.73 ? 525 LEU A CD2 1 ATOM 3807 N N . ARG A 1 473 ? -28.905 26.128 -6.777 1.00 37.24 ? 526 ARG A N 1 ATOM 3808 C CA . ARG A 1 473 ? -29.622 26.375 -8.030 1.00 36.41 ? 526 ARG A CA 1 ATOM 3809 C C . ARG A 1 473 ? -30.938 27.087 -7.772 1.00 37.61 ? 526 ARG A C 1 ATOM 3810 O O . ARG A 1 473 ? -31.734 27.301 -8.692 1.00 37.43 ? 526 ARG A O 1 ATOM 3811 C CB . ARG A 1 473 ? -29.882 25.063 -8.762 1.00 35.90 ? 526 ARG A CB 1 ATOM 3812 C CG . ARG A 1 473 ? -28.646 24.212 -8.903 1.00 35.00 ? 526 ARG A CG 1 ATOM 3813 C CD . ARG A 1 473 ? -27.584 24.825 -9.804 1.00 34.58 ? 526 ARG A CD 1 ATOM 3814 N NE . ARG A 1 473 ? -26.673 23.811 -10.314 1.00 33.62 ? 526 ARG A NE 1 ATOM 3815 C CZ . ARG A 1 473 ? -25.363 23.953 -10.359 1.00 34.21 ? 526 ARG A CZ 1 ATOM 3816 N NH1 . ARG A 1 473 ? -24.811 25.074 -9.925 1.00 34.36 ? 526 ARG A NH1 1 ATOM 3817 N NH2 . ARG A 1 473 ? -24.603 22.976 -10.837 1.00 35.09 ? 526 ARG A NH2 1 ATOM 3818 N N . GLU A 1 474 ? -31.162 27.456 -6.515 1.00 37.71 ? 527 GLU A N 1 ATOM 3819 C CA . GLU A 1 474 ? -32.351 28.214 -6.148 1.00 37.06 ? 527 GLU A CA 1 ATOM 3820 C C . GLU A 1 474 ? -32.077 29.710 -6.232 1.00 33.79 ? 527 GLU A C 1 ATOM 3821 O O . GLU A 1 474 ? -30.941 30.149 -6.126 1.00 32.81 ? 527 GLU A O 1 ATOM 3822 C CB . GLU A 1 474 ? -32.799 27.840 -4.732 1.00 38.76 ? 527 GLU A CB 1 ATOM 3823 C CG . GLU A 1 474 ? -33.623 26.566 -4.652 1.00 41.64 ? 527 GLU A CG 1 ATOM 3824 C CD . GLU A 1 474 ? -34.789 26.542 -5.637 1.00 44.09 ? 527 GLU A CD 1 ATOM 3825 O OE1 . GLU A 1 474 ? -35.551 27.543 -5.713 1.00 44.26 ? 527 GLU A OE1 1 ATOM 3826 O OE2 . GLU A 1 474 ? -34.945 25.512 -6.331 1.00 45.08 ? 527 GLU A OE2 1 ATOM 3827 N N . LYS A 1 475 ? -33.128 30.493 -6.413 1.00 34.74 ? 528 LYS A N 1 ATOM 3828 C CA . LYS A 1 475 ? -33.019 31.938 -6.331 1.00 36.90 ? 528 LYS A CA 1 ATOM 3829 C C . LYS A 1 475 ? -32.841 32.371 -4.878 1.00 36.84 ? 528 LYS A C 1 ATOM 3830 O O . LYS A 1 475 ? -33.082 31.589 -3.961 1.00 34.46 ? 528 LYS A O 1 ATOM 3831 C CB . LYS A 1 475 ? -34.270 32.588 -6.909 1.00 38.91 ? 528 LYS A CB 1 ATOM 3832 C CG . LYS A 1 475 ? -34.300 32.644 -8.421 1.00 42.27 ? 528 LYS A CG 1 ATOM 3833 C CD . LYS A 1 475 ? -34.897 33.970 -8.906 1.00 44.95 ? 528 LYS A CD 1 ATOM 3834 C CE . LYS A 1 475 ? -35.400 33.878 -10.348 1.00 46.08 ? 528 LYS A CE 1 ATOM 3835 N NZ . LYS A 1 475 ? -36.898 33.886 -10.414 1.00 46.81 ? 528 LYS A NZ 1 ATOM 3836 N N . VAL A 1 476 ? -32.428 33.621 -4.677 1.00 36.56 ? 529 VAL A N 1 ATOM 3837 C CA . VAL A 1 476 ? -32.491 34.261 -3.370 1.00 36.13 ? 529 VAL A CA 1 ATOM 3838 C C . VAL A 1 476 ? -33.898 34.746 -3.053 1.00 37.36 ? 529 VAL A C 1 ATOM 3839 O O . VAL A 1 476 ? -34.509 35.446 -3.852 1.00 38.82 ? 529 VAL A O 1 ATOM 3840 C CB . VAL A 1 476 ? -31.553 35.482 -3.319 1.00 35.12 ? 529 VAL A CB 1 ATOM 3841 C CG1 . VAL A 1 476 ? -31.292 35.904 -1.877 1.00 33.38 ? 529 VAL A CG1 1 ATOM 3842 C CG2 . VAL A 1 476 ? -30.265 35.178 -4.042 1.00 34.08 ? 529 VAL A CG2 1 ATOM 3843 N N . ASP A 1 477 ? -34.410 34.399 -1.881 1.00 39.42 ? 530 ASP A N 1 ATOM 3844 C CA . ASP A 1 477 ? -35.697 34.928 -1.463 1.00 41.66 ? 530 ASP A CA 1 ATOM 3845 C C . ASP A 1 477 ? -35.522 36.309 -0.859 1.00 44.21 ? 530 ASP A C 1 ATOM 3846 O O . ASP A 1 477 ? -34.750 36.488 0.083 1.00 41.11 ? 530 ASP A O 1 ATOM 3847 C CB . ASP A 1 477 ? -36.364 34.028 -0.432 1.00 43.37 ? 530 ASP A CB 1 ATOM 3848 C CG . ASP A 1 477 ? -37.646 34.633 0.106 1.00 44.84 ? 530 ASP A CG 1 ATOM 3849 O OD1 . ASP A 1 477 ? -37.936 35.799 -0.245 1.00 47.49 ? 530 ASP A OD1 1 ATOM 3850 O OD2 . ASP A 1 477 ? -38.421 34.034 0.876 1.00 47.89 ? 530 ASP A OD2 1 ATOM 3851 N N . LYS A 1 478 ? -36.256 37.277 -1.390 1.00 46.43 ? 531 LYS A N 1 ATOM 3852 C CA . LYS A 1 478 ? -36.102 38.666 -0.976 1.00 48.21 ? 531 LYS A CA 1 ATOM 3853 C C . LYS A 1 478 ? -37.016 38.952 0.214 1.00 46.24 ? 531 LYS A C 1 ATOM 3854 O O . LYS A 1 478 ? -37.009 40.055 0.770 1.00 43.46 ? 531 LYS A O 1 ATOM 3855 C CB . LYS A 1 478 ? -36.416 39.606 -2.146 1.00 50.57 ? 531 LYS A CB 1 ATOM 3856 C CG . LYS A 1 478 ? -35.743 39.200 -3.462 1.00 52.39 ? 531 LYS A CG 1 ATOM 3857 C CD . LYS A 1 478 ? -36.359 39.906 -4.674 1.00 54.27 ? 531 LYS A CD 1 ATOM 3858 C CE . LYS A 1 478 ? -35.542 41.130 -5.105 1.00 54.71 ? 531 LYS A CE 1 ATOM 3859 N NZ . LYS A 1 478 ? -34.725 40.873 -6.340 1.00 54.87 ? 531 LYS A NZ 1 ATOM 3860 N N . ASP A 1 479 ? -37.788 37.940 0.601 1.00 45.03 ? 532 ASP A N 1 ATOM 3861 C CA . ASP A 1 479 ? -38.587 37.984 1.820 1.00 46.38 ? 532 ASP A CA 1 ATOM 3862 C C . ASP A 1 479 ? -37.689 37.841 3.043 1.00 43.60 ? 532 ASP A C 1 ATOM 3863 O O . ASP A 1 479 ? -38.056 38.233 4.143 1.00 46.20 ? 532 ASP A O 1 ATOM 3864 C CB . ASP A 1 479 ? -39.604 36.831 1.839 1.00 48.72 ? 532 ASP A CB 1 ATOM 3865 C CG . ASP A 1 479 ? -40.835 37.104 0.986 1.00 52.17 ? 532 ASP A CG 1 ATOM 3866 O OD1 . ASP A 1 479 ? -40.981 38.247 0.494 1.00 54.39 ? 532 ASP A OD1 1 ATOM 3867 O OD2 . ASP A 1 479 ? -41.711 36.224 0.761 1.00 53.40 ? 532 ASP A OD2 1 ATOM 3868 N N . GLU A 1 480 ? -36.535 37.222 2.864 1.00 40.41 ? 533 GLU A N 1 ATOM 3869 C CA . GLU A 1 480 ? -35.858 36.605 3.988 1.00 41.10 ? 533 GLU A CA 1 ATOM 3870 C C . GLU A 1 480 ? -35.215 37.701 4.826 1.00 35.86 ? 533 GLU A C 1 ATOM 3871 O O . GLU A 1 480 ? -34.560 38.579 4.291 1.00 34.02 ? 533 GLU A O 1 ATOM 3872 C CB . GLU A 1 480 ? -34.803 35.618 3.498 1.00 43.33 ? 533 GLU A CB 1 ATOM 3873 C CG . GLU A 1 480 ? -34.856 34.253 4.160 1.00 46.04 ? 533 GLU A CG 1 ATOM 3874 C CD . GLU A 1 480 ? -33.577 33.463 3.952 1.00 49.52 ? 533 GLU A CD 1 ATOM 3875 O OE1 . GLU A 1 480 ? -33.503 32.689 2.971 1.00 50.72 ? 533 GLU A OE1 1 ATOM 3876 O OE2 . GLU A 1 480 ? -32.641 33.620 4.769 1.00 52.44 ? 533 GLU A OE2 1 ATOM 3877 N N . TRP A 1 481 ? -35.419 37.655 6.137 1.00 33.41 ? 534 TRP A N 1 ATOM 3878 C CA . TRP A 1 481 ? -34.685 38.529 7.054 1.00 29.57 ? 534 TRP A CA 1 ATOM 3879 C C . TRP A 1 481 ? -33.304 37.958 7.321 1.00 27.90 ? 534 TRP A C 1 ATOM 3880 O O . TRP A 1 481 ? -33.119 36.747 7.356 1.00 24.84 ? 534 TRP A O 1 ATOM 3881 C CB . TRP A 1 481 ? -35.441 38.676 8.381 1.00 28.68 ? 534 TRP A CB 1 ATOM 3882 C CG . TRP A 1 481 ? -36.586 39.635 8.324 1.00 27.73 ? 534 TRP A CG 1 ATOM 3883 C CD1 . TRP A 1 481 ? -37.607 39.633 7.427 1.00 26.13 ? 534 TRP A CD1 1 ATOM 3884 C CD2 . TRP A 1 481 ? -36.835 40.735 9.205 1.00 28.20 ? 534 TRP A CD2 1 ATOM 3885 N NE1 . TRP A 1 481 ? -38.473 40.663 7.692 1.00 25.76 ? 534 TRP A NE1 1 ATOM 3886 C CE2 . TRP A 1 481 ? -38.018 41.357 8.777 1.00 27.93 ? 534 TRP A CE2 1 ATOM 3887 C CE3 . TRP A 1 481 ? -36.172 41.266 10.306 1.00 27.06 ? 534 TRP A CE3 1 ATOM 3888 C CZ2 . TRP A 1 481 ? -38.544 42.469 9.410 1.00 29.06 ? 534 TRP A CZ2 1 ATOM 3889 C CZ3 . TRP A 1 481 ? -36.701 42.367 10.931 1.00 27.88 ? 534 TRP A CZ3 1 ATOM 3890 C CH2 . TRP A 1 481 ? -37.870 42.956 10.483 1.00 28.17 ? 534 TRP A CH2 1 ATOM 3891 N N . ILE A 1 482 ? -32.331 38.833 7.532 1.00 30.35 ? 535 ILE A N 1 ATOM 3892 C CA . ILE A 1 482 ? -30.968 38.392 7.777 1.00 30.75 ? 535 ILE A CA 1 ATOM 3893 C C . ILE A 1 482 ? -30.613 38.520 9.254 1.00 30.38 ? 535 ILE A C 1 ATOM 3894 O O . ILE A 1 482 ? -29.454 38.390 9.639 1.00 31.69 ? 535 ILE A O 1 ATOM 3895 C CB . ILE A 1 482 ? -30.012 39.227 6.947 1.00 30.95 ? 535 ILE A CB 1 ATOM 3896 C CG1 . ILE A 1 482 ? -29.987 40.655 7.484 1.00 30.28 ? 535 ILE A CG1 1 ATOM 3897 C CG2 . ILE A 1 482 ? -30.436 39.180 5.479 1.00 32.35 ? 535 ILE A CG2 1 ATOM 3898 C CD1 . ILE A 1 482 ? -28.799 41.459 7.026 1.00 32.75 ? 535 ILE A CD1 1 ATOM 3899 N N . SER A 1 483 ? -31.615 38.795 10.075 1.00 29.03 ? 536 SER A N 1 ATOM 3900 C CA . SER A 1 483 ? -31.451 38.733 11.523 1.00 28.77 ? 536 SER A CA 1 ATOM 3901 C C . SER A 1 483 ? -32.780 38.352 12.134 1.00 27.07 ? 536 SER A C 1 ATOM 3902 O O . SER A 1 483 ? -33.829 38.736 11.625 1.00 27.80 ? 536 SER A O 1 ATOM 3903 C CB . SER A 1 483 ? -30.998 40.082 12.074 1.00 27.85 ? 536 SER A CB 1 ATOM 3904 O OG . SER A 1 483 ? -30.931 40.045 13.482 1.00 28.42 ? 536 SER A OG 1 ATOM 3905 N N . GLY A 1 484 ? -32.736 37.588 13.218 1.00 25.42 ? 537 GLY A N 1 ATOM 3906 C CA . GLY A 1 484 ? -33.893 37.425 14.066 1.00 21.37 ? 537 GLY A CA 1 ATOM 3907 C C . GLY A 1 484 ? -34.178 38.706 14.815 1.00 18.81 ? 537 GLY A C 1 ATOM 3908 O O . GLY A 1 484 ? -33.365 39.621 14.782 1.00 18.21 ? 537 GLY A O 1 ATOM 3909 N N . ALA A 1 485 ? -35.323 38.754 15.497 1.00 16.07 ? 538 ALA A N 1 ATOM 3910 C CA . ALA A 1 485 ? -35.765 39.948 16.213 1.00 17.34 ? 538 ALA A CA 1 ATOM 3911 C C . ALA A 1 485 ? -35.081 40.091 17.564 1.00 16.23 ? 538 ALA A C 1 ATOM 3912 O O . ALA A 1 485 ? -34.902 41.202 18.061 1.00 19.34 ? 538 ALA A O 1 ATOM 3913 C CB . ALA A 1 485 ? -37.250 39.912 16.405 1.00 16.08 ? 538 ALA A CB 1 ATOM 3914 N N . ALA A 1 486 ? -34.708 38.964 18.162 1.00 19.87 ? 539 ALA A N 1 ATOM 3915 C CA . ALA A 1 486 ? -34.199 38.959 19.529 1.00 18.10 ? 539 ALA A CA 1 ATOM 3916 C C . ALA A 1 486 ? -32.677 39.108 19.539 1.00 16.29 ? 539 ALA A C 1 ATOM 3917 O O . ALA A 1 486 ? -31.952 38.186 19.917 1.00 16.71 ? 539 ALA A O 1 ATOM 3918 C CB . ALA A 1 486 ? -34.620 37.691 20.242 1.00 16.89 ? 539 ALA A CB 1 ATOM 3919 N N . VAL A 1 487 ? -32.222 40.285 19.119 1.00 15.65 ? 540 VAL A N 1 ATOM 3920 C CA . VAL A 1 487 ? -30.827 40.559 18.800 1.00 14.87 ? 540 VAL A CA 1 ATOM 3921 C C . VAL A 1 487 ? -30.636 42.060 19.051 1.00 15.52 ? 540 VAL A C 1 ATOM 3922 O O . VAL A 1 487 ? -31.402 42.885 18.547 1.00 16.57 ? 540 VAL A O 1 ATOM 3923 C CB . VAL A 1 487 ? -30.478 40.221 17.316 1.00 17.28 ? 540 VAL A CB 1 ATOM 3924 C CG1 . VAL A 1 487 ? -29.055 40.649 16.987 1.00 15.91 ? 540 VAL A CG1 1 ATOM 3925 C CG2 . VAL A 1 487 ? -30.686 38.717 16.995 1.00 16.85 ? 540 VAL A CG2 1 ATOM 3926 N N . VAL A 1 488 ? -29.642 42.397 19.865 1.00 13.61 ? 541 VAL A N 1 ATOM 3927 C CA . VAL A 1 488 ? -29.230 43.765 20.074 1.00 15.19 ? 541 VAL A CA 1 ATOM 3928 C C . VAL A 1 488 ? -28.153 44.130 19.071 1.00 16.18 ? 541 VAL A C 1 ATOM 3929 O O . VAL A 1 488 ? -26.970 44.013 19.349 1.00 18.85 ? 541 VAL A O 1 ATOM 3930 C CB . VAL A 1 488 ? -28.697 43.954 21.499 1.00 16.31 ? 541 VAL A CB 1 ATOM 3931 C CG1 . VAL A 1 488 ? -28.160 45.337 21.687 1.00 16.61 ? 541 VAL A CG1 1 ATOM 3932 C CG2 . VAL A 1 488 ? -29.814 43.682 22.519 1.00 20.02 ? 541 VAL A CG2 1 ATOM 3933 N N . ASN A 1 489 ? -28.585 44.549 17.886 1.00 16.64 ? 542 ASN A N 1 ATOM 3934 C CA . ASN A 1 489 ? -27.699 44.904 16.787 1.00 16.98 ? 542 ASN A CA 1 ATOM 3935 C C . ASN A 1 489 ? -28.525 45.487 15.645 1.00 19.35 ? 542 ASN A C 1 ATOM 3936 O O . ASN A 1 489 ? -29.755 45.532 15.718 1.00 17.40 ? 542 ASN A O 1 ATOM 3937 C CB . ASN A 1 489 ? -26.941 43.666 16.287 1.00 17.54 ? 542 ASN A CB 1 ATOM 3938 C CG . ASN A 1 489 ? -25.525 43.984 15.841 1.00 18.00 ? 542 ASN A CG 1 ATOM 3939 O OD1 . ASN A 1 489 ? -25.231 45.102 15.440 1.00 19.05 ? 542 ASN A OD1 1 ATOM 3940 N ND2 . ASN A 1 489 ? -24.639 42.996 15.925 1.00 18.03 ? 542 ASN A ND2 1 ATOM 3941 N N . ALA A 1 490 ? -27.840 45.925 14.596 1.00 18.85 ? 543 ALA A N 1 ATOM 3942 C CA . ALA A 1 490 ? -28.470 46.275 13.332 1.00 19.57 ? 543 ALA A CA 1 ATOM 3943 C C . ALA A 1 490 ? -27.522 45.942 12.173 1.00 18.32 ? 543 ALA A C 1 ATOM 3944 O O . ALA A 1 490 ? -26.346 45.693 12.384 1.00 16.94 ? 543 ALA A O 1 ATOM 3945 C CB . ALA A 1 490 ? -28.831 47.764 13.316 1.00 19.66 ? 543 ALA A CB 1 ATOM 3946 N N . PHE A 1 491 ? -28.039 45.932 10.954 1.00 21.00 ? 544 PHE A N 1 ATOM 3947 C CA . PHE A 1 491 ? -27.354 45.282 9.848 1.00 25.69 ? 544 PHE A CA 1 ATOM 3948 C C . PHE A 1 491 ? -27.546 46.020 8.528 1.00 24.23 ? 544 PHE A C 1 ATOM 3949 O O . PHE A 1 491 ? -28.578 46.633 8.299 1.00 25.05 ? 544 PHE A O 1 ATOM 3950 C CB . PHE A 1 491 ? -27.828 43.836 9.709 1.00 26.46 ? 544 PHE A CB 1 ATOM 3951 C CG . PHE A 1 491 ? -27.664 43.033 10.955 1.00 30.55 ? 544 PHE A CG 1 ATOM 3952 C CD1 . PHE A 1 491 ? -26.516 42.289 11.169 1.00 32.02 ? 544 PHE A CD1 1 ATOM 3953 C CD2 . PHE A 1 491 ? -28.653 43.029 11.928 1.00 30.40 ? 544 PHE A CD2 1 ATOM 3954 C CE1 . PHE A 1 491 ? -26.363 41.547 12.333 1.00 33.55 ? 544 PHE A CE1 1 ATOM 3955 C CE2 . PHE A 1 491 ? -28.501 42.292 13.087 1.00 31.73 ? 544 PHE A CE2 1 ATOM 3956 C CZ . PHE A 1 491 ? -27.360 41.546 13.288 1.00 32.08 ? 544 PHE A CZ 1 ATOM 3957 N N . TYR A 1 492 ? -26.534 45.944 7.670 1.00 24.07 ? 545 TYR A N 1 ATOM 3958 C CA . TYR A 1 492 ? -26.667 46.273 6.254 1.00 22.62 ? 545 TYR A CA 1 ATOM 3959 C C . TYR A 1 492 ? -26.206 45.092 5.415 1.00 24.04 ? 545 TYR A C 1 ATOM 3960 O O . TYR A 1 492 ? -25.125 44.541 5.629 1.00 21.77 ? 545 TYR A O 1 ATOM 3961 C CB . TYR A 1 492 ? -25.845 47.508 5.884 1.00 23.61 ? 545 TYR A CB 1 ATOM 3962 C CG . TYR A 1 492 ? -25.879 47.792 4.398 1.00 24.59 ? 545 TYR A CG 1 ATOM 3963 C CD1 . TYR A 1 492 ? -26.970 48.435 3.825 1.00 25.63 ? 545 TYR A CD1 1 ATOM 3964 C CD2 . TYR A 1 492 ? -24.837 47.401 3.567 1.00 21.36 ? 545 TYR A CD2 1 ATOM 3965 C CE1 . TYR A 1 492 ? -27.022 48.675 2.469 1.00 24.42 ? 545 TYR A CE1 1 ATOM 3966 C CE2 . TYR A 1 492 ? -24.884 47.633 2.211 1.00 23.97 ? 545 TYR A CE2 1 ATOM 3967 C CZ . TYR A 1 492 ? -25.975 48.273 1.669 1.00 23.32 ? 545 TYR A CZ 1 ATOM 3968 O OH . TYR A 1 492 ? -26.020 48.514 0.318 1.00 20.61 ? 545 TYR A OH 1 ATOM 3969 N N . SER A 1 493 ? -27.050 44.688 4.475 1.00 24.58 ? 546 SER A N 1 ATOM 3970 C CA . SER A 1 493 ? -26.680 43.681 3.503 1.00 25.48 ? 546 SER A CA 1 ATOM 3971 C C . SER A 1 493 ? -26.498 44.345 2.151 1.00 25.77 ? 546 SER A C 1 ATOM 3972 O O . SER A 1 493 ? -27.415 44.993 1.647 1.00 25.01 ? 546 SER A O 1 ATOM 3973 C CB . SER A 1 493 ? -27.785 42.642 3.397 1.00 25.90 ? 546 SER A CB 1 ATOM 3974 O OG . SER A 1 493 ? -27.765 42.021 2.126 1.00 28.61 ? 546 SER A OG 1 ATOM 3975 N N . SER A 1 494 ? -25.322 44.188 1.556 1.00 27.87 ? 547 SER A N 1 ATOM 3976 C CA . SER A 1 494 ? -25.047 44.866 0.296 1.00 31.50 ? 547 SER A CA 1 ATOM 3977 C C . SER A 1 494 ? -25.645 44.054 -0.850 1.00 31.56 ? 547 SER A C 1 ATOM 3978 O O . SER A 1 494 ? -26.078 44.614 -1.847 1.00 30.27 ? 547 SER A O 1 ATOM 3979 C CB . SER A 1 494 ? -23.544 45.114 0.097 1.00 31.34 ? 547 SER A CB 1 ATOM 3980 O OG . SER A 1 494 ? -22.788 43.924 0.231 1.00 34.46 ? 547 SER A OG 1 ATOM 3981 N N . GLY A 1 495 ? -25.699 42.737 -0.668 1.00 30.93 ? 548 GLY A N 1 ATOM 3982 C CA . GLY A 1 495 ? -26.405 41.846 -1.572 1.00 32.60 ? 548 GLY A CA 1 ATOM 3983 C C . GLY A 1 495 ? -27.908 42.052 -1.631 1.00 33.52 ? 548 GLY A C 1 ATOM 3984 O O . GLY A 1 495 ? -28.529 41.829 -2.669 1.00 31.84 ? 548 GLY A O 1 ATOM 3985 N N . ARG A 1 496 ? -28.496 42.468 -0.514 1.00 34.17 ? 549 ARG A N 1 ATOM 3986 C CA . ARG A 1 496 ? -29.930 42.704 -0.448 1.00 33.32 ? 549 ARG A CA 1 ATOM 3987 C C . ARG A 1 496 ? -30.172 44.201 -0.482 1.00 32.67 ? 549 ARG A C 1 ATOM 3988 O O . ARG A 1 496 ? -31.306 44.669 -0.563 1.00 35.43 ? 549 ARG A O 1 ATOM 3989 C CB . ARG A 1 496 ? -30.513 42.097 0.829 1.00 36.25 ? 549 ARG A CB 1 ATOM 3990 C CG . ARG A 1 496 ? -30.781 40.606 0.725 1.00 38.16 ? 549 ARG A CG 1 ATOM 3991 C CD . ARG A 1 496 ? -30.738 39.856 2.042 1.00 42.16 ? 549 ARG A CD 1 ATOM 3992 N NE . ARG A 1 496 ? -31.402 38.570 1.895 1.00 47.14 ? 549 ARG A NE 1 ATOM 3993 C CZ . ARG A 1 496 ? -32.645 38.439 1.457 1.00 51.55 ? 549 ARG A CZ 1 ATOM 3994 N NH1 . ARG A 1 496 ? -33.352 39.519 1.149 1.00 53.56 ? 549 ARG A NH1 1 ATOM 3995 N NH2 . ARG A 1 496 ? -33.186 37.233 1.334 1.00 53.32 ? 549 ARG A NH2 1 ATOM 3996 N N . ASN A 1 497 ? -29.082 44.952 -0.421 1.00 31.13 ? 550 ASN A N 1 ATOM 3997 C CA . ASN A 1 497 ? -29.152 46.395 -0.247 1.00 28.70 ? 550 ASN A CA 1 ATOM 3998 C C . ASN A 1 497 ? -30.251 46.783 0.736 1.00 29.67 ? 550 ASN A C 1 ATOM 3999 O O . ASN A 1 497 ? -31.165 47.533 0.401 1.00 27.69 ? 550 ASN A O 1 ATOM 4000 C CB . ASN A 1 497 ? -29.375 47.071 -1.596 1.00 28.47 ? 550 ASN A CB 1 ATOM 4001 C CG . ASN A 1 497 ? -29.412 48.585 -1.499 1.00 27.37 ? 550 ASN A CG 1 ATOM 4002 O OD1 . ASN A 1 497 ? -30.071 49.246 -2.304 1.00 26.58 ? 550 ASN A OD1 1 ATOM 4003 N ND2 . ASN A 1 497 ? -28.697 49.145 -0.524 1.00 24.93 ? 550 ASN A ND2 1 ATOM 4004 N N . GLN A 1 498 ? -30.142 46.273 1.958 1.00 28.46 ? 551 GLN A N 1 ATOM 4005 C CA . GLN A 1 498 ? -31.237 46.322 2.914 1.00 27.77 ? 551 GLN A CA 1 ATOM 4006 C C . GLN A 1 498 ? -30.713 46.664 4.306 1.00 25.16 ? 551 GLN A C 1 ATOM 4007 O O . GLN A 1 498 ? -29.643 46.210 4.706 1.00 24.74 ? 551 GLN A O 1 ATOM 4008 C CB . GLN A 1 498 ? -31.970 44.984 2.913 1.00 28.36 ? 551 GLN A CB 1 ATOM 4009 C CG . GLN A 1 498 ? -32.185 44.333 4.259 1.00 29.17 ? 551 GLN A CG 1 ATOM 4010 C CD . GLN A 1 498 ? -33.078 43.116 4.133 1.00 30.73 ? 551 GLN A CD 1 ATOM 4011 O OE1 . GLN A 1 498 ? -33.837 43.010 3.169 1.00 35.15 ? 551 GLN A OE1 1 ATOM 4012 N NE2 . GLN A 1 498 ? -32.980 42.187 5.081 1.00 31.99 ? 551 GLN A NE2 1 ATOM 4013 N N . ILE A 1 499 ? -31.462 47.489 5.021 1.00 21.14 ? 552 ILE A N 1 ATOM 4014 C CA . ILE A 1 499 ? -31.133 47.826 6.396 1.00 18.78 ? 552 ILE A CA 1 ATOM 4015 C C . ILE A 1 499 ? -32.129 47.134 7.318 1.00 20.39 ? 552 ILE A C 1 ATOM 4016 O O . ILE A 1 499 ? -33.333 47.077 7.035 1.00 19.67 ? 552 ILE A O 1 ATOM 4017 C CB . ILE A 1 499 ? -31.145 49.346 6.629 1.00 15.49 ? 552 ILE A CB 1 ATOM 4018 C CG1 . ILE A 1 499 ? -32.426 49.981 6.102 1.00 14.90 ? 552 ILE A CG1 1 ATOM 4019 C CG2 . ILE A 1 499 ? -29.947 50.017 5.972 1.00 14.62 ? 552 ILE A CG2 1 ATOM 4020 C CD1 . ILE A 1 499 ? -32.547 51.464 6.466 1.00 15.13 ? 552 ILE A CD1 1 ATOM 4021 N N . VAL A 1 500 ? -31.600 46.578 8.402 1.00 20.04 ? 553 VAL A N 1 ATOM 4022 C CA . VAL A 1 500 ? -32.381 45.797 9.341 1.00 18.96 ? 553 VAL A CA 1 ATOM 4023 C C . VAL A 1 500 ? -32.161 46.300 10.749 1.00 17.21 ? 553 VAL A C 1 ATOM 4024 O O . VAL A 1 500 ? -31.032 46.485 11.186 1.00 14.74 ? 553 VAL A O 1 ATOM 4025 C CB . VAL A 1 500 ? -31.985 44.342 9.305 1.00 20.61 ? 553 VAL A CB 1 ATOM 4026 C CG1 . VAL A 1 500 ? -33.040 43.506 10.020 1.00 21.53 ? 553 VAL A CG1 1 ATOM 4027 C CG2 . VAL A 1 500 ? -31.809 43.893 7.878 1.00 23.76 ? 553 VAL A CG2 1 ATOM 4028 N N . PHE A 1 501 ? -33.254 46.529 11.457 1.00 20.50 ? 554 PHE A N 1 ATOM 4029 C CA . PHE A 1 501 ? -33.189 46.932 12.853 1.00 21.27 ? 554 PHE A CA 1 ATOM 4030 C C . PHE A 1 501 ? -34.122 46.059 13.670 1.00 19.43 ? 554 PHE A C 1 ATOM 4031 O O . PHE A 1 501 ? -35.303 46.335 13.759 1.00 19.62 ? 554 PHE A O 1 ATOM 4032 C CB . PHE A 1 501 ? -33.586 48.398 12.981 1.00 23.43 ? 554 PHE A CB 1 ATOM 4033 C CG . PHE A 1 501 ? -32.846 49.311 12.033 1.00 24.04 ? 554 PHE A CG 1 ATOM 4034 C CD1 . PHE A 1 501 ? -31.697 49.966 12.439 1.00 23.89 ? 554 PHE A CD1 1 ATOM 4035 C CD2 . PHE A 1 501 ? -33.306 49.511 10.740 1.00 25.41 ? 554 PHE A CD2 1 ATOM 4036 C CE1 . PHE A 1 501 ? -31.012 50.793 11.570 1.00 25.12 ? 554 PHE A CE1 1 ATOM 4037 C CE2 . PHE A 1 501 ? -32.630 50.351 9.862 1.00 26.28 ? 554 PHE A CE2 1 ATOM 4038 C CZ . PHE A 1 501 ? -31.485 50.992 10.273 1.00 25.97 ? 554 PHE A CZ 1 ATOM 4039 N N . PRO A 1 502 ? -33.578 44.999 14.256 1.00 19.80 ? 555 PRO A N 1 ATOM 4040 C CA . PRO A 1 502 ? -34.332 44.101 15.142 1.00 16.93 ? 555 PRO A CA 1 ATOM 4041 C C . PRO A 1 502 ? -34.919 44.763 16.401 1.00 16.81 ? 555 PRO A C 1 ATOM 4042 O O . PRO A 1 502 ? -34.306 45.656 16.989 1.00 18.27 ? 555 PRO A O 1 ATOM 4043 C CB . PRO A 1 502 ? -33.293 43.049 15.532 1.00 17.83 ? 555 PRO A CB 1 ATOM 4044 C CG . PRO A 1 502 ? -32.219 43.134 14.491 1.00 15.67 ? 555 PRO A CG 1 ATOM 4045 C CD . PRO A 1 502 ? -32.184 44.560 14.073 1.00 17.55 ? 555 PRO A CD 1 ATOM 4046 N N . ALA A 1 503 ? -36.107 44.298 16.790 1.00 17.38 ? 556 ALA A N 1 ATOM 4047 C CA . ALA A 1 503 ? -36.746 44.629 18.062 1.00 18.60 ? 556 ALA A CA 1 ATOM 4048 C C . ALA A 1 503 ? -35.699 44.919 19.142 1.00 15.93 ? 556 ALA A C 1 ATOM 4049 O O . ALA A 1 503 ? -35.784 45.919 19.816 1.00 13.56 ? 556 ALA A O 1 ATOM 4050 C CB . ALA A 1 503 ? -37.646 43.492 18.494 1.00 19.09 ? 556 ALA A CB 1 ATOM 4051 N N . GLY A 1 504 ? -34.722 44.035 19.291 1.00 16.94 ? 557 GLY A N 1 ATOM 4052 C CA . GLY A 1 504 ? -33.763 44.109 20.388 1.00 17.90 ? 557 GLY A CA 1 ATOM 4053 C C . GLY A 1 504 ? -32.949 45.394 20.524 1.00 17.43 ? 557 GLY A C 1 ATOM 4054 O O . GLY A 1 504 ? -32.573 45.766 21.637 1.00 18.92 ? 557 GLY A O 1 ATOM 4055 N N . ILE A 1 505 ? -32.661 46.083 19.425 1.00 17.73 ? 558 ILE A N 1 ATOM 4056 C CA . ILE A 1 505 ? -31.914 47.345 19.518 1.00 17.82 ? 558 ILE A CA 1 ATOM 4057 C C . ILE A 1 505 ? -32.848 48.555 19.658 1.00 18.71 ? 558 ILE A C 1 ATOM 4058 O O . ILE A 1 505 ? -32.389 49.681 19.861 1.00 21.53 ? 558 ILE A O 1 ATOM 4059 C CB . ILE A 1 505 ? -30.956 47.519 18.313 1.00 18.87 ? 558 ILE A CB 1 ATOM 4060 C CG1 . ILE A 1 505 ? -29.837 48.516 18.642 1.00 20.25 ? 558 ILE A CG1 1 ATOM 4061 C CG2 . ILE A 1 505 ? -31.726 47.984 17.090 1.00 19.38 ? 558 ILE A CG2 1 ATOM 4062 C CD1 . ILE A 1 505 ? -28.474 48.174 18.029 1.00 18.13 ? 558 ILE A CD1 1 ATOM 4063 N N . LEU A 1 506 ? -34.152 48.319 19.567 1.00 16.50 ? 559 LEU A N 1 ATOM 4064 C CA . LEU A 1 506 ? -35.127 49.404 19.570 1.00 20.76 ? 559 LEU A CA 1 ATOM 4065 C C . LEU A 1 506 ? -35.669 49.639 20.977 1.00 22.34 ? 559 LEU A C 1 ATOM 4066 O O . LEU A 1 506 ? -36.864 49.505 21.239 1.00 18.78 ? 559 LEU A O 1 ATOM 4067 C CB . LEU A 1 506 ? -36.285 49.106 18.620 1.00 22.49 ? 559 LEU A CB 1 ATOM 4068 C CG . LEU A 1 506 ? -35.883 48.861 17.165 1.00 25.18 ? 559 LEU A CG 1 ATOM 4069 C CD1 . LEU A 1 506 ? -37.113 48.655 16.295 1.00 26.02 ? 559 LEU A CD1 1 ATOM 4070 C CD2 . LEU A 1 506 ? -35.039 50.013 16.641 1.00 27.62 ? 559 LEU A CD2 1 ATOM 4071 N N . GLN A 1 507 ? -34.768 50.014 21.872 1.00 22.61 ? 560 GLN A N 1 ATOM 4072 C CA . GLN A 1 507 ? -35.111 50.272 23.259 1.00 20.42 ? 560 GLN A CA 1 ATOM 4073 C C . GLN A 1 507 ? -34.049 51.200 23.805 1.00 18.18 ? 560 GLN A C 1 ATOM 4074 O O . GLN A 1 507 ? -33.026 51.424 23.167 1.00 16.29 ? 560 GLN A O 1 ATOM 4075 C CB . GLN A 1 507 ? -35.140 48.967 24.046 1.00 20.61 ? 560 GLN A CB 1 ATOM 4076 C CG . GLN A 1 507 ? -33.829 48.226 24.018 1.00 21.57 ? 560 GLN A CG 1 ATOM 4077 C CD . GLN A 1 507 ? -33.843 47.025 24.935 1.00 21.67 ? 560 GLN A CD 1 ATOM 4078 O OE1 . GLN A 1 507 ? -34.124 47.162 26.123 1.00 19.97 ? 560 GLN A OE1 1 ATOM 4079 N NE2 . GLN A 1 507 ? -33.522 45.845 24.393 1.00 17.55 ? 560 GLN A NE2 1 ATOM 4080 N N . PRO A 1 508 ? -34.280 51.773 24.970 1.00 17.46 ? 561 PRO A N 1 ATOM 4081 C CA . PRO A 1 508 ? -33.299 52.708 25.506 1.00 16.57 ? 561 PRO A CA 1 ATOM 4082 C C . PRO A 1 508 ? -31.977 51.987 25.705 1.00 16.55 ? 561 PRO A C 1 ATOM 4083 O O . PRO A 1 508 ? -31.959 50.793 25.964 1.00 17.43 ? 561 PRO A O 1 ATOM 4084 C CB . PRO A 1 508 ? -33.928 53.156 26.818 1.00 17.73 ? 561 PRO A CB 1 ATOM 4085 C CG . PRO A 1 508 ? -35.403 52.888 26.618 1.00 18.78 ? 561 PRO A CG 1 ATOM 4086 C CD . PRO A 1 508 ? -35.444 51.608 25.852 1.00 15.97 ? 561 PRO A CD 1 ATOM 4087 N N . PRO A 1 509 ? -30.872 52.700 25.562 1.00 17.40 ? 562 PRO A N 1 ATOM 4088 C CA . PRO A 1 509 ? -30.884 54.144 25.341 1.00 17.90 ? 562 PRO A CA 1 ATOM 4089 C C . PRO A 1 509 ? -31.057 54.556 23.871 1.00 18.25 ? 562 PRO A C 1 ATOM 4090 O O . PRO A 1 509 ? -31.084 55.758 23.585 1.00 18.81 ? 562 PRO A O 1 ATOM 4091 C CB . PRO A 1 509 ? -29.503 54.556 25.843 1.00 15.71 ? 562 PRO A CB 1 ATOM 4092 C CG . PRO A 1 509 ? -28.639 53.346 25.585 1.00 14.30 ? 562 PRO A CG 1 ATOM 4093 C CD . PRO A 1 509 ? -29.504 52.158 25.631 1.00 15.22 ? 562 PRO A CD 1 ATOM 4094 N N . PHE A 1 510 ? -31.155 53.587 22.962 1.00 17.79 ? 563 PHE A N 1 ATOM 4095 C CA . PHE A 1 510 ? -31.266 53.889 21.531 1.00 14.94 ? 563 PHE A CA 1 ATOM 4096 C C . PHE A 1 510 ? -32.607 54.501 21.187 1.00 17.69 ? 563 PHE A C 1 ATOM 4097 O O . PHE A 1 510 ? -32.675 55.519 20.498 1.00 19.21 ? 563 PHE A O 1 ATOM 4098 C CB . PHE A 1 510 ? -31.111 52.629 20.686 1.00 13.86 ? 563 PHE A CB 1 ATOM 4099 C CG . PHE A 1 510 ? -29.761 51.990 20.788 1.00 16.15 ? 563 PHE A CG 1 ATOM 4100 C CD1 . PHE A 1 510 ? -28.698 52.459 20.040 1.00 14.74 ? 563 PHE A CD1 1 ATOM 4101 C CD2 . PHE A 1 510 ? -29.559 50.918 21.622 1.00 14.88 ? 563 PHE A CD2 1 ATOM 4102 C CE1 . PHE A 1 510 ? -27.469 51.863 20.132 1.00 15.72 ? 563 PHE A CE1 1 ATOM 4103 C CE2 . PHE A 1 510 ? -28.327 50.326 21.711 1.00 16.33 ? 563 PHE A CE2 1 ATOM 4104 C CZ . PHE A 1 510 ? -27.280 50.805 20.981 1.00 12.91 ? 563 PHE A CZ 1 ATOM 4105 N N . PHE A 1 511 ? -33.683 53.852 21.622 1.00 17.29 ? 564 PHE A N 1 ATOM 4106 C CA . PHE A 1 511 ? -35.009 54.285 21.227 1.00 18.52 ? 564 PHE A CA 1 ATOM 4107 C C . PHE A 1 511 ? -36.084 54.104 22.289 1.00 18.86 ? 564 PHE A C 1 ATOM 4108 O O . PHE A 1 511 ? -36.238 53.028 22.878 1.00 16.77 ? 564 PHE A O 1 ATOM 4109 C CB . PHE A 1 511 ? -35.472 53.571 19.968 1.00 20.70 ? 564 PHE A CB 1 ATOM 4110 C CG . PHE A 1 511 ? -36.844 53.968 19.565 1.00 20.22 ? 564 PHE A CG 1 ATOM 4111 C CD1 . PHE A 1 511 ? -37.075 55.227 19.051 1.00 20.54 ? 564 PHE A CD1 1 ATOM 4112 C CD2 . PHE A 1 511 ? -37.912 53.123 19.774 1.00 20.81 ? 564 PHE A CD2 1 ATOM 4113 C CE1 . PHE A 1 511 ? -38.335 55.618 18.700 1.00 20.04 ? 564 PHE A CE1 1 ATOM 4114 C CE2 . PHE A 1 511 ? -39.181 53.518 19.440 1.00 21.14 ? 564 PHE A CE2 1 ATOM 4115 C CZ . PHE A 1 511 ? -39.391 54.763 18.897 1.00 20.31 ? 564 PHE A CZ 1 ATOM 4116 N N . SER A 1 512 ? -36.866 55.157 22.494 1.00 20.02 ? 565 SER A N 1 ATOM 4117 C CA . SER A 1 512 ? -38.200 55.000 23.071 1.00 19.64 ? 565 SER A CA 1 ATOM 4118 C C . SER A 1 512 ? -39.117 56.122 22.630 1.00 17.58 ? 565 SER A C 1 ATOM 4119 O O . SER A 1 512 ? -38.734 57.296 22.614 1.00 21.61 ? 565 SER A O 1 ATOM 4120 C CB . SER A 1 512 ? -38.122 54.976 24.602 1.00 20.64 ? 565 SER A CB 1 ATOM 4121 O OG . SER A 1 512 ? -39.395 55.186 25.193 1.00 17.59 ? 565 SER A OG 1 ATOM 4122 N N . ALA A 1 513 ? -40.339 55.755 22.288 1.00 20.62 ? 566 ALA A N 1 ATOM 4123 C CA . ALA A 1 513 ? -41.337 56.724 21.875 1.00 21.84 ? 566 ALA A CA 1 ATOM 4124 C C . ALA A 1 513 ? -41.620 57.664 23.028 1.00 23.68 ? 566 ALA A C 1 ATOM 4125 O O . ALA A 1 513 ? -42.170 58.748 22.845 1.00 25.57 ? 566 ALA A O 1 ATOM 4126 C CB . ALA A 1 513 ? -42.592 56.016 21.449 1.00 20.74 ? 566 ALA A CB 1 ATOM 4127 N N . GLN A 1 514 ? -41.243 57.247 24.228 1.00 25.84 ? 567 GLN A N 1 ATOM 4128 C CA . GLN A 1 514 ? -41.491 58.066 25.401 1.00 30.31 ? 567 GLN A CA 1 ATOM 4129 C C . GLN A 1 514 ? -40.290 58.941 25.793 1.00 29.15 ? 567 GLN A C 1 ATOM 4130 O O . GLN A 1 514 ? -40.470 59.969 26.442 1.00 33.09 ? 567 GLN A O 1 ATOM 4131 C CB . GLN A 1 514 ? -41.940 57.184 26.563 1.00 36.27 ? 567 GLN A CB 1 ATOM 4132 C CG . GLN A 1 514 ? -43.429 56.841 26.526 1.00 38.91 ? 567 GLN A CG 1 ATOM 4133 C CD . GLN A 1 514 ? -43.776 55.869 25.408 1.00 44.15 ? 567 GLN A CD 1 ATOM 4134 O OE1 . GLN A 1 514 ? -43.103 54.847 25.237 1.00 47.91 ? 567 GLN A OE1 1 ATOM 4135 N NE2 . GLN A 1 514 ? -44.825 56.182 24.645 1.00 44.31 ? 567 GLN A NE2 1 ATOM 4136 N N . GLN A 1 515 ? -39.079 58.572 25.374 1.00 26.32 ? 568 GLN A N 1 ATOM 4137 C CA . GLN A 1 515 ? -37.894 59.377 25.699 1.00 23.04 ? 568 GLN A CA 1 ATOM 4138 C C . GLN A 1 515 ? -37.773 60.555 24.740 1.00 20.78 ? 568 GLN A C 1 ATOM 4139 O O . GLN A 1 515 ? -38.499 60.630 23.762 1.00 21.83 ? 568 GLN A O 1 ATOM 4140 C CB . GLN A 1 515 ? -36.609 58.531 25.705 1.00 22.40 ? 568 GLN A CB 1 ATOM 4141 C CG . GLN A 1 515 ? -35.847 58.442 24.370 1.00 20.05 ? 568 GLN A CG 1 ATOM 4142 C CD . GLN A 1 515 ? -34.704 57.426 24.428 1.00 21.29 ? 568 GLN A CD 1 ATOM 4143 O OE1 . GLN A 1 515 ? -34.404 56.899 25.499 1.00 22.06 ? 568 GLN A OE1 1 ATOM 4144 N NE2 . GLN A 1 515 ? -34.064 57.158 23.286 1.00 17.50 ? 568 GLN A NE2 1 ATOM 4145 N N . SER A 1 516 ? -36.872 61.482 25.039 1.00 19.09 ? 569 SER A N 1 ATOM 4146 C CA . SER A 1 516 ? -36.701 62.676 24.213 1.00 21.63 ? 569 SER A CA 1 ATOM 4147 C C . SER A 1 516 ? -36.173 62.333 22.826 1.00 21.19 ? 569 SER A C 1 ATOM 4148 O O . SER A 1 516 ? -35.330 61.452 22.660 1.00 21.70 ? 569 SER A O 1 ATOM 4149 C CB . SER A 1 516 ? -35.759 63.671 24.879 1.00 19.13 ? 569 SER A CB 1 ATOM 4150 O OG . SER A 1 516 ? -36.118 63.886 26.231 1.00 22.72 ? 569 SER A OG 1 ATOM 4151 N N . ASN A 1 517 ? -36.678 63.044 21.831 1.00 22.85 ? 570 ASN A N 1 ATOM 4152 C CA . ASN A 1 517 ? -36.263 62.835 20.453 1.00 23.53 ? 570 ASN A CA 1 ATOM 4153 C C . ASN A 1 517 ? -34.762 63.004 20.319 1.00 22.41 ? 570 ASN A C 1 ATOM 4154 O O . ASN A 1 517 ? -34.100 62.253 19.601 1.00 22.99 ? 570 ASN A O 1 ATOM 4155 C CB . ASN A 1 517 ? -36.994 63.812 19.525 1.00 24.23 ? 570 ASN A CB 1 ATOM 4156 C CG . ASN A 1 517 ? -38.497 63.616 19.545 1.00 27.17 ? 570 ASN A CG 1 ATOM 4157 O OD1 . ASN A 1 517 ? -39.006 62.588 19.102 1.00 30.18 ? 570 ASN A OD1 1 ATOM 4158 N ND2 . ASN A 1 517 ? -39.214 64.598 20.075 1.00 27.49 ? 570 ASN A ND2 1 ATOM 4159 N N . SER A 1 518 ? -34.221 63.993 21.015 1.00 24.28 ? 571 SER A N 1 ATOM 4160 C CA . SER A 1 518 ? -32.779 64.218 20.993 1.00 27.07 ? 571 SER A CA 1 ATOM 4161 C C . SER A 1 518 ? -32.024 62.933 21.333 1.00 26.00 ? 571 SER A C 1 ATOM 4162 O O . SER A 1 518 ? -31.049 62.576 20.661 1.00 28.38 ? 571 SER A O 1 ATOM 4163 C CB . SER A 1 518 ? -32.397 65.301 21.989 1.00 26.43 ? 571 SER A CB 1 ATOM 4164 O OG . SER A 1 518 ? -32.580 64.828 23.304 1.00 29.75 ? 571 SER A OG 1 ATOM 4165 N N . LEU A 1 519 ? -32.474 62.251 22.383 1.00 22.17 ? 572 LEU A N 1 ATOM 4166 C CA . LEU A 1 519 ? -31.927 60.951 22.739 1.00 22.66 ? 572 LEU A CA 1 ATOM 4167 C C . LEU A 1 519 ? -32.176 59.938 21.625 1.00 20.85 ? 572 LEU A C 1 ATOM 4168 O O . LEU A 1 519 ? -31.297 59.129 21.288 1.00 17.29 ? 572 LEU A O 1 ATOM 4169 C CB . LEU A 1 519 ? -32.526 60.451 24.057 1.00 20.47 ? 572 LEU A CB 1 ATOM 4170 C CG . LEU A 1 519 ? -32.367 61.420 25.235 1.00 20.67 ? 572 LEU A CG 1 ATOM 4171 C CD1 . LEU A 1 519 ? -32.900 60.810 26.520 1.00 19.82 ? 572 LEU A CD1 1 ATOM 4172 C CD2 . LEU A 1 519 ? -30.924 61.856 25.417 1.00 17.04 ? 572 LEU A CD2 1 ATOM 4173 N N . ASN A 1 520 ? -33.366 59.986 21.046 1.00 18.04 ? 573 ASN A N 1 ATOM 4174 C CA . ASN A 1 520 ? -33.690 59.060 19.976 1.00 20.02 ? 573 ASN A CA 1 ATOM 4175 C C . ASN A 1 520 ? -32.773 59.233 18.783 1.00 22.06 ? 573 ASN A C 1 ATOM 4176 O O . ASN A 1 520 ? -32.262 58.257 18.241 1.00 16.59 ? 573 ASN A O 1 ATOM 4177 C CB . ASN A 1 520 ? -35.138 59.220 19.552 1.00 20.83 ? 573 ASN A CB 1 ATOM 4178 C CG . ASN A 1 520 ? -36.080 58.562 20.517 1.00 22.62 ? 573 ASN A CG 1 ATOM 4179 O OD1 . ASN A 1 520 ? -35.720 57.580 21.180 1.00 25.02 ? 573 ASN A OD1 1 ATOM 4180 N ND2 . ASN A 1 520 ? -37.285 59.097 20.626 1.00 19.67 ? 573 ASN A ND2 1 ATOM 4181 N N . TYR A 1 521 ? -32.574 60.482 18.377 1.00 21.90 ? 574 TYR A N 1 ATOM 4182 C CA . TYR A 1 521 ? -31.890 60.766 17.130 1.00 23.36 ? 574 TYR A CA 1 ATOM 4183 C C . TYR A 1 521 ? -30.385 60.513 17.314 1.00 21.67 ? 574 TYR A C 1 ATOM 4184 O O . TYR A 1 521 ? -29.683 60.135 16.375 1.00 20.51 ? 574 TYR A O 1 ATOM 4185 C CB . TYR A 1 521 ? -32.122 62.218 16.714 1.00 25.40 ? 574 TYR A CB 1 ATOM 4186 C CG . TYR A 1 521 ? -33.407 62.459 15.954 1.00 25.89 ? 574 TYR A CG 1 ATOM 4187 C CD1 . TYR A 1 521 ? -33.436 62.410 14.567 1.00 28.36 ? 574 TYR A CD1 1 ATOM 4188 C CD2 . TYR A 1 521 ? -34.581 62.759 16.623 1.00 25.46 ? 574 TYR A CD2 1 ATOM 4189 C CE1 . TYR A 1 521 ? -34.607 62.640 13.865 1.00 28.16 ? 574 TYR A CE1 1 ATOM 4190 C CE2 . TYR A 1 521 ? -35.749 62.983 15.937 1.00 27.45 ? 574 TYR A CE2 1 ATOM 4191 C CZ . TYR A 1 521 ? -35.759 62.926 14.557 1.00 27.71 ? 574 TYR A CZ 1 ATOM 4192 O OH . TYR A 1 521 ? -36.923 63.161 13.876 1.00 23.58 ? 574 TYR A OH 1 ATOM 4193 N N . GLY A 1 522 ? -29.909 60.716 18.538 1.00 19.20 ? 575 GLY A N 1 ATOM 4194 C CA . GLY A 1 522 ? -28.516 60.477 18.863 1.00 18.98 ? 575 GLY A CA 1 ATOM 4195 C C . GLY A 1 522 ? -28.221 59.011 19.121 1.00 16.97 ? 575 GLY A C 1 ATOM 4196 O O . GLY A 1 522 ? -27.068 58.586 19.109 1.00 17.09 ? 575 GLY A O 1 ATOM 4197 N N . GLY A 1 523 ? -29.276 58.243 19.350 1.00 15.96 ? 576 GLY A N 1 ATOM 4198 C CA . GLY A 1 523 ? -29.167 56.818 19.584 1.00 15.56 ? 576 GLY A CA 1 ATOM 4199 C C . GLY A 1 523 ? -29.530 56.058 18.332 1.00 15.49 ? 576 GLY A C 1 ATOM 4200 O O . GLY A 1 523 ? -28.679 55.789 17.493 1.00 17.11 ? 576 GLY A O 1 ATOM 4201 N N . ILE A 1 524 ? -30.804 55.722 18.177 1.00 20.33 ? 577 ILE A N 1 ATOM 4202 C CA . ILE A 1 524 ? -31.206 54.900 17.039 1.00 19.61 ? 577 ILE A CA 1 ATOM 4203 C C . ILE A 1 524 ? -31.026 55.667 15.732 1.00 17.97 ? 577 ILE A C 1 ATOM 4204 O O . ILE A 1 524 ? -30.693 55.083 14.698 1.00 17.95 ? 577 ILE A O 1 ATOM 4205 C CB . ILE A 1 524 ? -32.631 54.372 17.194 1.00 21.49 ? 577 ILE A CB 1 ATOM 4206 C CG1 . ILE A 1 524 ? -32.682 52.918 16.724 1.00 23.25 ? 577 ILE A CG1 1 ATOM 4207 C CG2 . ILE A 1 524 ? -33.624 55.229 16.408 1.00 23.36 ? 577 ILE A CG2 1 ATOM 4208 C CD1 . ILE A 1 524 ? -31.608 52.045 17.325 1.00 26.67 ? 577 ILE A CD1 1 ATOM 4209 N N . GLY A 1 525 ? -31.210 56.979 15.782 1.00 16.33 ? 578 GLY A N 1 ATOM 4210 C CA . GLY A 1 525 ? -31.057 57.796 14.590 1.00 19.24 ? 578 GLY A CA 1 ATOM 4211 C C . GLY A 1 525 ? -29.648 57.744 14.026 1.00 19.29 ? 578 GLY A C 1 ATOM 4212 O O . GLY A 1 525 ? -29.457 57.566 12.829 1.00 19.71 ? 578 GLY A O 1 ATOM 4213 N N . MET A 1 526 ? -28.663 57.912 14.900 1.00 19.32 ? 579 MET A N 1 ATOM 4214 C CA . MET A 1 526 ? -27.267 57.686 14.559 1.00 20.60 ? 579 MET A CA 1 ATOM 4215 C C . MET A 1 526 ? -27.084 56.274 14.003 1.00 22.52 ? 579 MET A C 1 ATOM 4216 O O . MET A 1 526 ? -26.352 56.073 13.035 1.00 23.27 ? 579 MET A O 1 ATOM 4217 C CB . MET A 1 526 ? -26.400 57.908 15.796 1.00 22.29 ? 579 MET A CB 1 ATOM 4218 C CG . MET A 1 526 ? -24.908 57.815 15.556 1.00 23.88 ? 579 MET A CG 1 ATOM 4219 S SD . MET A 1 526 ? -24.348 56.114 15.592 1.00 23.32 ? 579 MET A SD 1 ATOM 4220 C CE . MET A 1 526 ? -24.808 55.642 17.260 1.00 26.97 ? 579 MET A CE 1 ATOM 4221 N N . VAL A 1 527 ? -27.782 55.301 14.589 1.00 21.48 ? 580 VAL A N 1 ATOM 4222 C CA . VAL A 1 527 ? -27.637 53.905 14.178 1.00 19.84 ? 580 VAL A CA 1 ATOM 4223 C C . VAL A 1 527 ? -28.187 53.662 12.760 1.00 18.53 ? 580 VAL A C 1 ATOM 4224 O O . VAL A 1 527 ? -27.549 53.017 11.938 1.00 18.55 ? 580 VAL A O 1 ATOM 4225 C CB . VAL A 1 527 ? -28.335 52.958 15.178 1.00 19.70 ? 580 VAL A CB 1 ATOM 4226 C CG1 . VAL A 1 527 ? -28.332 51.523 14.648 1.00 19.24 ? 580 VAL A CG1 1 ATOM 4227 C CG2 . VAL A 1 527 ? -27.663 53.034 16.540 1.00 19.46 ? 580 VAL A CG2 1 ATOM 4228 N N . ILE A 1 528 ? -29.367 54.197 12.475 1.00 19.04 ? 581 ILE A N 1 ATOM 4229 C CA . ILE A 1 528 ? -29.934 54.121 11.134 1.00 15.65 ? 581 ILE A CA 1 ATOM 4230 C C . ILE A 1 528 ? -29.030 54.733 10.058 1.00 14.45 ? 581 ILE A C 1 ATOM 4231 O O . ILE A 1 528 ? -28.932 54.200 8.958 1.00 17.21 ? 581 ILE A O 1 ATOM 4232 C CB . ILE A 1 528 ? -31.306 54.804 11.089 1.00 15.19 ? 581 ILE A CB 1 ATOM 4233 C CG1 . ILE A 1 528 ? -32.224 54.255 12.188 1.00 14.71 ? 581 ILE A CG1 1 ATOM 4234 C CG2 . ILE A 1 528 ? -31.948 54.607 9.708 1.00 14.72 ? 581 ILE A CG2 1 ATOM 4235 C CD1 . ILE A 1 528 ? -33.520 55.061 12.370 1.00 13.83 ? 581 ILE A CD1 1 ATOM 4236 N N . GLY A 1 529 ? -28.392 55.856 10.361 1.00 15.93 ? 582 GLY A N 1 ATOM 4237 C CA . GLY A 1 529 ? -27.433 56.454 9.440 1.00 15.86 ? 582 GLY A CA 1 ATOM 4238 C C . GLY A 1 529 ? -26.170 55.618 9.270 1.00 19.72 ? 582 GLY A C 1 ATOM 4239 O O . GLY A 1 529 ? -25.679 55.440 8.160 1.00 22.47 ? 582 GLY A O 1 ATOM 4240 N N . HIS A 1 530 ? -25.648 55.101 10.377 1.00 20.21 ? 583 HIS A N 1 ATOM 4241 C CA . HIS A 1 530 ? -24.598 54.090 10.333 1.00 18.91 ? 583 HIS A CA 1 ATOM 4242 C C . HIS A 1 530 ? -24.951 53.086 9.257 1.00 18.34 ? 583 HIS A C 1 ATOM 4243 O O . HIS A 1 530 ? -24.173 52.845 8.331 1.00 16.69 ? 583 HIS A O 1 ATOM 4244 C CB . HIS A 1 530 ? -24.457 53.414 11.713 1.00 17.72 ? 583 HIS A CB 1 ATOM 4245 C CG . HIS A 1 530 ? -23.347 52.408 11.803 1.00 15.30 ? 583 HIS A CG 1 ATOM 4246 N ND1 . HIS A 1 530 ? -22.030 52.762 11.986 1.00 14.58 ? 583 HIS A ND1 1 ATOM 4247 C CD2 . HIS A 1 530 ? -23.371 51.054 11.784 1.00 15.02 ? 583 HIS A CD2 1 ATOM 4248 C CE1 . HIS A 1 530 ? -21.285 51.671 12.025 1.00 16.79 ? 583 HIS A CE1 1 ATOM 4249 N NE2 . HIS A 1 530 ? -22.078 50.619 11.923 1.00 12.08 ? 583 HIS A NE2 1 ATOM 4250 N N . GLU A 1 531 ? -26.130 52.489 9.373 1.00 20.86 ? 584 GLU A N 1 ATOM 4251 C CA . GLU A 1 531 ? -26.450 51.318 8.561 1.00 20.19 ? 584 GLU A CA 1 ATOM 4252 C C . GLU A 1 531 ? -26.590 51.719 7.096 1.00 18.52 ? 584 GLU A C 1 ATOM 4253 O O . GLU A 1 531 ? -26.158 50.996 6.207 1.00 15.73 ? 584 GLU A O 1 ATOM 4254 C CB . GLU A 1 531 ? -27.749 50.669 9.042 1.00 20.41 ? 584 GLU A CB 1 ATOM 4255 C CG . GLU A 1 531 ? -27.623 49.981 10.378 1.00 20.16 ? 584 GLU A CG 1 ATOM 4256 C CD . GLU A 1 531 ? -26.387 49.110 10.465 1.00 21.16 ? 584 GLU A CD 1 ATOM 4257 O OE1 . GLU A 1 531 ? -26.074 48.429 9.460 1.00 22.12 ? 584 GLU A OE1 1 ATOM 4258 O OE2 . GLU A 1 531 ? -25.735 49.106 11.537 1.00 17.26 ? 584 GLU A OE2 1 ATOM 4259 N N . ILE A 1 532 ? -27.206 52.874 6.863 1.00 18.20 ? 585 ILE A N 1 ATOM 4260 C CA . ILE A 1 532 ? -27.349 53.417 5.520 1.00 18.71 ? 585 ILE A CA 1 ATOM 4261 C C . ILE A 1 532 ? -25.980 53.714 4.942 1.00 18.57 ? 585 ILE A C 1 ATOM 4262 O O . ILE A 1 532 ? -25.671 53.356 3.810 1.00 19.58 ? 585 ILE A O 1 ATOM 4263 C CB . ILE A 1 532 ? -28.169 54.712 5.552 1.00 19.11 ? 585 ILE A CB 1 ATOM 4264 C CG1 . ILE A 1 532 ? -29.642 54.403 5.766 1.00 17.92 ? 585 ILE A CG1 1 ATOM 4265 C CG2 . ILE A 1 532 ? -27.997 55.484 4.244 1.00 22.10 ? 585 ILE A CG2 1 ATOM 4266 C CD1 . ILE A 1 532 ? -30.462 55.611 6.073 1.00 16.19 ? 585 ILE A CD1 1 ATOM 4267 N N . THR A 1 533 ? -25.149 54.361 5.738 1.00 20.66 ? 586 THR A N 1 ATOM 4268 C CA . THR A 1 533 ? -23.852 54.783 5.263 1.00 21.90 ? 586 THR A CA 1 ATOM 4269 C C . THR A 1 533 ? -23.014 53.586 4.850 1.00 21.32 ? 586 THR A C 1 ATOM 4270 O O . THR A 1 533 ? -22.097 53.725 4.054 1.00 24.32 ? 586 THR A O 1 ATOM 4271 C CB . THR A 1 533 ? -23.155 55.607 6.336 1.00 25.10 ? 586 THR A CB 1 ATOM 4272 O OG1 . THR A 1 533 ? -23.872 56.835 6.526 1.00 26.00 ? 586 THR A OG1 1 ATOM 4273 C CG2 . THR A 1 533 ? -21.772 56.046 5.873 1.00 25.60 ? 586 THR A CG2 1 ATOM 4274 N N . HIS A 1 534 ? -23.336 52.402 5.363 1.00 23.27 ? 587 HIS A N 1 ATOM 4275 C CA . HIS A 1 534 ? -22.527 51.227 5.070 1.00 24.32 ? 587 HIS A CA 1 ATOM 4276 C C . HIS A 1 534 ? -22.696 50.875 3.607 1.00 21.60 ? 587 HIS A C 1 ATOM 4277 O O . HIS A 1 534 ? -21.856 50.188 3.027 1.00 14.74 ? 587 HIS A O 1 ATOM 4278 C CB . HIS A 1 534 ? -22.973 49.997 5.866 1.00 29.07 ? 587 HIS A CB 1 ATOM 4279 C CG . HIS A 1 534 ? -22.409 49.893 7.252 1.00 32.74 ? 587 HIS A CG 1 ATOM 4280 N ND1 . HIS A 1 534 ? -21.058 49.797 7.494 1.00 38.35 ? 587 HIS A ND1 1 ATOM 4281 C CD2 . HIS A 1 534 ? -23.010 49.782 8.458 1.00 37.88 ? 587 HIS A CD2 1 ATOM 4282 C CE1 . HIS A 1 534 ? -20.847 49.661 8.789 1.00 36.41 ? 587 HIS A CE1 1 ATOM 4283 N NE2 . HIS A 1 534 ? -22.016 49.649 9.397 1.00 38.03 ? 587 HIS A NE2 1 ATOM 4284 N N . GLY A 1 535 ? -23.830 51.282 3.041 1.00 21.99 ? 588 GLY A N 1 ATOM 4285 C CA . GLY A 1 535 ? -24.117 51.034 1.643 1.00 20.29 ? 588 GLY A CA 1 ATOM 4286 C C . GLY A 1 535 ? -23.145 51.816 0.786 1.00 21.58 ? 588 GLY A C 1 ATOM 4287 O O . GLY A 1 535 ? -23.027 51.581 -0.408 1.00 25.40 ? 588 GLY A O 1 ATOM 4288 N N . PHE A 1 536 ? -22.432 52.740 1.412 1.00 23.66 ? 589 PHE A N 1 ATOM 4289 C CA . PHE A 1 536 ? -21.598 53.664 0.678 1.00 24.57 ? 589 PHE A CA 1 ATOM 4290 C C . PHE A 1 536 ? -20.231 53.759 1.338 1.00 24.13 ? 589 PHE A C 1 ATOM 4291 O O . PHE A 1 536 ? -19.498 54.759 1.157 1.00 23.17 ? 589 PHE A O 1 ATOM 4292 C CB . PHE A 1 536 ? -22.245 55.044 0.657 1.00 24.07 ? 589 PHE A CB 1 ATOM 4293 C CG . PHE A 1 536 ? -23.637 55.060 0.095 1.00 23.53 ? 589 PHE A CG 1 ATOM 4294 C CD1 . PHE A 1 536 ? -23.846 55.291 -1.252 1.00 22.66 ? 589 PHE A CD1 1 ATOM 4295 C CD2 . PHE A 1 536 ? -24.736 54.881 0.918 1.00 21.30 ? 589 PHE A CD2 1 ATOM 4296 C CE1 . PHE A 1 536 ? -25.117 55.325 -1.774 1.00 22.71 ? 589 PHE A CE1 1 ATOM 4297 C CE2 . PHE A 1 536 ? -26.009 54.933 0.407 1.00 24.12 ? 589 PHE A CE2 1 ATOM 4298 C CZ . PHE A 1 536 ? -26.205 55.145 -0.942 1.00 23.84 ? 589 PHE A CZ 1 ATOM 4299 N N . ASP A 1 537 ? -19.887 52.735 2.119 1.00 22.93 ? 590 ASP A N 1 ATOM 4300 C CA . ASP A 1 537 ? -18.538 52.645 2.666 1.00 23.31 ? 590 ASP A CA 1 ATOM 4301 C C . ASP A 1 537 ? -17.656 51.850 1.713 1.00 22.98 ? 590 ASP A C 1 ATOM 4302 O O . ASP A 1 537 ? -18.025 51.621 0.564 1.00 19.93 ? 590 ASP A O 1 ATOM 4303 C CB . ASP A 1 537 ? -18.537 52.047 4.075 1.00 21.88 ? 590 ASP A CB 1 ATOM 4304 C CG . ASP A 1 537 ? -18.641 50.549 4.077 1.00 21.50 ? 590 ASP A CG 1 ATOM 4305 O OD1 . ASP A 1 537 ? -18.500 49.932 2.999 1.00 22.10 ? 590 ASP A OD1 1 ATOM 4306 O OD2 . ASP A 1 537 ? -18.875 49.898 5.123 1.00 22.93 ? 590 ASP A OD2 1 ATOM 4307 N N . ASP A 1 538 ? -16.466 51.484 2.171 1.00 24.23 ? 591 ASP A N 1 ATOM 4308 C CA . ASP A 1 538 ? -15.395 51.114 1.259 1.00 26.19 ? 591 ASP A CA 1 ATOM 4309 C C . ASP A 1 538 ? -15.657 49.714 0.679 1.00 26.39 ? 591 ASP A C 1 ATOM 4310 O O . ASP A 1 538 ? -15.053 49.332 -0.314 1.00 18.91 ? 591 ASP A O 1 ATOM 4311 C CB . ASP A 1 538 ? -14.049 51.156 1.982 1.00 29.51 ? 591 ASP A CB 1 ATOM 4312 C CG . ASP A 1 538 ? -14.007 50.223 3.172 1.00 32.65 ? 591 ASP A CG 1 ATOM 4313 O OD1 . ASP A 1 538 ? -14.942 50.286 4.003 1.00 33.58 ? 591 ASP A OD1 1 ATOM 4314 O OD2 . ASP A 1 538 ? -13.095 49.384 3.343 1.00 33.98 ? 591 ASP A OD2 1 ATOM 4315 N N . ASN A 1 539 ? -16.568 48.953 1.294 1.00 25.53 ? 592 ASN A N 1 ATOM 4316 C CA . ASN A 1 539 ? -17.087 47.718 0.694 1.00 23.47 ? 592 ASN A CA 1 ATOM 4317 C C . ASN A 1 539 ? -18.356 47.997 -0.090 1.00 23.71 ? 592 ASN A C 1 ATOM 4318 O O . ASN A 1 539 ? -18.469 47.637 -1.258 1.00 24.47 ? 592 ASN A O 1 ATOM 4319 C CB . ASN A 1 539 ? -17.368 46.668 1.776 1.00 24.25 ? 592 ASN A CB 1 ATOM 4320 C CG . ASN A 1 539 ? -18.274 45.552 1.291 1.00 24.44 ? 592 ASN A CG 1 ATOM 4321 O OD1 . ASN A 1 539 ? -19.484 45.566 1.530 1.00 27.47 ? 592 ASN A OD1 1 ATOM 4322 N ND2 . ASN A 1 539 ? -17.691 44.563 0.624 1.00 26.27 ? 592 ASN A ND2 1 ATOM 4323 N N . GLY A 1 540 ? -19.314 48.639 0.570 1.00 24.39 ? 593 GLY A N 1 ATOM 4324 C CA . GLY A 1 540 ? -20.665 48.749 0.050 1.00 24.09 ? 593 GLY A CA 1 ATOM 4325 C C . GLY A 1 540 ? -20.750 49.655 -1.168 1.00 25.31 ? 593 GLY A C 1 ATOM 4326 O O . GLY A 1 540 ? -21.581 49.442 -2.049 1.00 23.47 ? 593 GLY A O 1 ATOM 4327 N N . ARG A 1 541 ? -19.892 50.666 -1.242 1.00 24.73 ? 594 ARG A N 1 ATOM 4328 C CA . ARG A 1 541 ? -19.939 51.557 -2.393 1.00 26.24 ? 594 ARG A CA 1 ATOM 4329 C C . ARG A 1 541 ? -19.804 50.748 -3.681 1.00 25.35 ? 594 ARG A C 1 ATOM 4330 O O . ARG A 1 541 ? -20.216 51.188 -4.740 1.00 28.54 ? 594 ARG A O 1 ATOM 4331 C CB . ARG A 1 541 ? -18.867 52.645 -2.303 1.00 26.46 ? 594 ARG A CB 1 ATOM 4332 C CG . ARG A 1 541 ? -17.479 52.213 -2.752 1.00 25.22 ? 594 ARG A CG 1 ATOM 4333 C CD . ARG A 1 541 ? -16.432 53.308 -2.636 1.00 26.77 ? 594 ARG A CD 1 ATOM 4334 N NE . ARG A 1 541 ? -15.152 52.851 -3.175 1.00 28.69 ? 594 ARG A NE 1 ATOM 4335 C CZ . ARG A 1 541 ? -14.845 52.864 -4.464 1.00 25.96 ? 594 ARG A CZ 1 ATOM 4336 N NH1 . ARG A 1 541 ? -15.715 53.339 -5.347 1.00 24.30 ? 594 ARG A NH1 1 ATOM 4337 N NH2 . ARG A 1 541 ? -13.669 52.402 -4.866 1.00 24.53 ? 594 ARG A NH2 1 ATOM 4338 N N . ASN A 1 542 ? -19.248 49.547 -3.576 1.00 26.97 ? 595 ASN A N 1 ATOM 4339 C CA . ASN A 1 542 ? -18.991 48.725 -4.746 1.00 24.31 ? 595 ASN A CA 1 ATOM 4340 C C . ASN A 1 542 ? -20.241 47.973 -5.197 1.00 25.36 ? 595 ASN A C 1 ATOM 4341 O O . ASN A 1 542 ? -20.259 47.348 -6.265 1.00 22.10 ? 595 ASN A O 1 ATOM 4342 C CB . ASN A 1 542 ? -17.859 47.731 -4.459 1.00 26.04 ? 595 ASN A CB 1 ATOM 4343 C CG . ASN A 1 542 ? -16.483 48.399 -4.409 1.00 28.40 ? 595 ASN A CG 1 ATOM 4344 O OD1 . ASN A 1 542 ? -15.926 48.764 -5.438 1.00 30.02 ? 595 ASN A OD1 1 ATOM 4345 N ND2 . ASN A 1 542 ? -15.934 48.557 -3.203 1.00 27.85 ? 595 ASN A ND2 1 ATOM 4346 N N . PHE A 1 543 ? -21.300 48.022 -4.398 1.00 24.56 ? 596 PHE A N 1 ATOM 4347 C CA . PHE A 1 543 ? -22.513 47.317 -4.781 1.00 25.17 ? 596 PHE A CA 1 ATOM 4348 C C . PHE A 1 543 ? -23.601 48.287 -5.206 1.00 25.83 ? 596 PHE A C 1 ATOM 4349 O O . PHE A 1 543 ? -23.687 49.403 -4.690 1.00 23.07 ? 596 PHE A O 1 ATOM 4350 C CB . PHE A 1 543 ? -23.002 46.403 -3.654 1.00 24.24 ? 596 PHE A CB 1 ATOM 4351 C CG . PHE A 1 543 ? -22.077 45.254 -3.353 1.00 22.09 ? 596 PHE A CG 1 ATOM 4352 C CD1 . PHE A 1 543 ? -22.347 43.992 -3.826 1.00 23.59 ? 596 PHE A CD1 1 ATOM 4353 C CD2 . PHE A 1 543 ? -20.946 45.441 -2.569 1.00 24.58 ? 596 PHE A CD2 1 ATOM 4354 C CE1 . PHE A 1 543 ? -21.503 42.916 -3.526 1.00 23.19 ? 596 PHE A CE1 1 ATOM 4355 C CE2 . PHE A 1 543 ? -20.094 44.386 -2.271 1.00 23.28 ? 596 PHE A CE2 1 ATOM 4356 C CZ . PHE A 1 543 ? -20.373 43.118 -2.753 1.00 23.57 ? 596 PHE A CZ 1 ATOM 4357 N N . ASN A 1 544 ? -24.422 47.871 -6.169 1.00 27.26 ? 597 ASN A N 1 ATOM 4358 C CA . ASN A 1 544 ? -25.372 48.797 -6.788 1.00 30.44 ? 597 ASN A CA 1 ATOM 4359 C C . ASN A 1 544 ? -26.768 48.634 -6.211 1.00 30.92 ? 597 ASN A C 1 ATOM 4360 O O . ASN A 1 544 ? -26.957 47.912 -5.238 1.00 33.81 ? 597 ASN A O 1 ATOM 4361 C CB . ASN A 1 544 ? -25.394 48.618 -8.312 1.00 30.90 ? 597 ASN A CB 1 ATOM 4362 C CG . ASN A 1 544 ? -26.210 47.404 -8.757 1.00 31.36 ? 597 ASN A CG 1 ATOM 4363 O OD1 . ASN A 1 544 ? -26.284 47.103 -9.954 1.00 30.70 ? 597 ASN A OD1 1 ATOM 4364 N ND2 . ASN A 1 544 ? -26.816 46.701 -7.800 1.00 30.09 ? 597 ASN A ND2 1 ATOM 4365 N N . LYS A 1 545 ? -27.748 49.304 -6.804 1.00 31.16 ? 598 LYS A N 1 ATOM 4366 C CA . LYS A 1 545 ? -29.046 49.444 -6.161 1.00 32.83 ? 598 LYS A CA 1 ATOM 4367 C C . LYS A 1 545 ? -29.710 48.082 -6.013 1.00 32.24 ? 598 LYS A C 1 ATOM 4368 O O . LYS A 1 545 ? -30.592 47.891 -5.179 1.00 33.63 ? 598 LYS A O 1 ATOM 4369 C CB . LYS A 1 545 ? -29.941 50.397 -6.948 1.00 34.16 ? 598 LYS A CB 1 ATOM 4370 C CG . LYS A 1 545 ? -30.497 49.805 -8.232 1.00 34.93 ? 598 LYS A CG 1 ATOM 4371 C CD . LYS A 1 545 ? -30.597 50.863 -9.323 1.00 35.82 ? 598 LYS A CD 1 ATOM 4372 C CE . LYS A 1 545 ? -32.031 51.058 -9.799 1.00 35.70 ? 598 LYS A CE 1 ATOM 4373 N NZ . LYS A 1 545 ? -32.484 49.945 -10.682 1.00 34.95 ? 598 LYS A NZ 1 ATOM 4374 N N . ASP A 1 546 ? -29.267 47.123 -6.810 1.00 32.56 ? 599 ASP A N 1 ATOM 4375 C CA . ASP A 1 546 ? -29.899 45.813 -6.827 1.00 31.71 ? 599 ASP A CA 1 ATOM 4376 C C . ASP A 1 546 ? -29.035 44.809 -6.075 1.00 31.74 ? 599 ASP A C 1 ATOM 4377 O O . ASP A 1 546 ? -29.311 43.605 -6.077 1.00 31.70 ? 599 ASP A O 1 ATOM 4378 C CB . ASP A 1 546 ? -30.125 45.363 -8.269 1.00 32.98 ? 599 ASP A CB 1 ATOM 4379 C CG . ASP A 1 546 ? -31.140 46.226 -8.990 1.00 35.66 ? 599 ASP A CG 1 ATOM 4380 O OD1 . ASP A 1 546 ? -32.203 46.517 -8.395 1.00 35.82 ? 599 ASP A OD1 1 ATOM 4381 O OD2 . ASP A 1 546 ? -30.960 46.671 -10.146 1.00 39.21 ? 599 ASP A OD2 1 ATOM 4382 N N . GLY A 1 547 ? -27.987 45.316 -5.429 1.00 32.01 ? 600 GLY A N 1 ATOM 4383 C CA . GLY A 1 547 ? -27.103 44.485 -4.626 1.00 31.60 ? 600 GLY A CA 1 ATOM 4384 C C . GLY A 1 547 ? -25.997 43.807 -5.418 1.00 30.63 ? 600 GLY A C 1 ATOM 4385 O O . GLY A 1 547 ? -25.292 42.947 -4.886 1.00 31.80 ? 600 GLY A O 1 ATOM 4386 N N . ASP A 1 548 ? -25.840 44.184 -6.687 1.00 28.75 ? 601 ASP A N 1 ATOM 4387 C CA . ASP A 1 548 ? -24.864 43.531 -7.561 1.00 27.26 ? 601 ASP A CA 1 ATOM 4388 C C . ASP A 1 548 ? -23.522 44.242 -7.508 1.00 23.27 ? 601 ASP A C 1 ATOM 4389 O O . ASP A 1 548 ? -23.447 45.468 -7.501 1.00 22.30 ? 601 ASP A O 1 ATOM 4390 C CB . ASP A 1 548 ? -25.357 43.487 -9.015 1.00 29.58 ? 601 ASP A CB 1 ATOM 4391 C CG . ASP A 1 548 ? -26.461 42.462 -9.229 1.00 31.61 ? 601 ASP A CG 1 ATOM 4392 O OD1 . ASP A 1 548 ? -26.358 41.329 -8.698 1.00 33.09 ? 601 ASP A OD1 1 ATOM 4393 O OD2 . ASP A 1 548 ? -27.477 42.710 -9.910 1.00 34.16 ? 601 ASP A OD2 1 ATOM 4394 N N . LEU A 1 549 ? -22.458 43.455 -7.497 1.00 23.79 ? 602 LEU A N 1 ATOM 4395 C CA . LEU A 1 549 ? -21.114 43.991 -7.476 1.00 26.17 ? 602 LEU A CA 1 ATOM 4396 C C . LEU A 1 549 ? -20.769 44.574 -8.847 1.00 28.79 ? 602 LEU A C 1 ATOM 4397 O O . LEU A 1 549 ? -20.345 43.862 -9.751 1.00 30.53 ? 602 LEU A O 1 ATOM 4398 C CB . LEU A 1 549 ? -20.139 42.882 -7.085 1.00 25.09 ? 602 LEU A CB 1 ATOM 4399 C CG . LEU A 1 549 ? -18.656 43.197 -7.225 1.00 24.75 ? 602 LEU A CG 1 ATOM 4400 C CD1 . LEU A 1 549 ? -18.320 44.392 -6.390 1.00 24.09 ? 602 LEU A CD1 1 ATOM 4401 C CD2 . LEU A 1 549 ? -17.816 42.000 -6.810 1.00 23.80 ? 602 LEU A CD2 1 ATOM 4402 N N . VAL A 1 550 ? -20.969 45.877 -8.993 1.00 31.06 ? 603 VAL A N 1 ATOM 4403 C CA . VAL A 1 550 ? -20.705 46.556 -10.246 1.00 32.53 ? 603 VAL A CA 1 ATOM 4404 C C . VAL A 1 550 ? -20.481 48.046 -10.040 1.00 32.32 ? 603 VAL A C 1 ATOM 4405 O O . VAL A 1 550 ? -21.193 48.698 -9.275 1.00 28.96 ? 603 VAL A O 1 ATOM 4406 C CB . VAL A 1 550 ? -21.861 46.386 -11.238 1.00 34.68 ? 603 VAL A CB 1 ATOM 4407 C CG1 . VAL A 1 550 ? -23.018 47.259 -10.849 1.00 34.36 ? 603 VAL A CG1 1 ATOM 4408 C CG2 . VAL A 1 550 ? -21.392 46.718 -12.660 1.00 35.74 ? 603 VAL A CG2 1 ATOM 4409 N N . ASP A 1 551 ? -19.489 48.572 -10.755 1.00 30.82 ? 604 ASP A N 1 ATOM 4410 C CA . ASP A 1 551 ? -18.939 49.890 -10.497 1.00 27.12 ? 604 ASP A CA 1 ATOM 4411 C C . ASP A 1 551 ? -19.865 50.952 -11.073 1.00 27.55 ? 604 ASP A C 1 ATOM 4412 O O . ASP A 1 551 ? -20.183 50.932 -12.262 1.00 28.71 ? 604 ASP A O 1 ATOM 4413 C CB . ASP A 1 551 ? -17.558 49.978 -11.139 1.00 27.22 ? 604 ASP A CB 1 ATOM 4414 C CG . ASP A 1 551 ? -16.864 51.291 -10.873 1.00 25.09 ? 604 ASP A CG 1 ATOM 4415 O OD1 . ASP A 1 551 ? -17.497 52.206 -10.306 1.00 24.38 ? 604 ASP A OD1 1 ATOM 4416 O OD2 . ASP A 1 551 ? -15.674 51.490 -11.198 1.00 24.87 ? 604 ASP A OD2 1 ATOM 4417 N N . TRP A 1 552 ? -20.308 51.873 -10.230 1.00 25.86 ? 605 TRP A N 1 ATOM 4418 C CA . TRP A 1 552 ? -21.165 52.958 -10.679 1.00 25.26 ? 605 TRP A CA 1 ATOM 4419 C C . TRP A 1 552 ? -20.544 54.286 -10.326 1.00 25.49 ? 605 TRP A C 1 ATOM 4420 O O . TRP A 1 552 ? -21.217 55.312 -10.269 1.00 20.45 ? 605 TRP A O 1 ATOM 4421 C CB . TRP A 1 552 ? -22.577 52.854 -10.083 1.00 25.05 ? 605 TRP A CB 1 ATOM 4422 C CG . TRP A 1 552 ? -22.666 52.612 -8.595 1.00 22.75 ? 605 TRP A CG 1 ATOM 4423 C CD1 . TRP A 1 552 ? -22.839 51.409 -7.977 1.00 24.54 ? 605 TRP A CD1 1 ATOM 4424 C CD2 . TRP A 1 552 ? -22.637 53.593 -7.551 1.00 20.45 ? 605 TRP A CD2 1 ATOM 4425 N NE1 . TRP A 1 552 ? -22.902 51.578 -6.614 1.00 24.61 ? 605 TRP A NE1 1 ATOM 4426 C CE2 . TRP A 1 552 ? -22.781 52.911 -6.327 1.00 22.10 ? 605 TRP A CE2 1 ATOM 4427 C CE3 . TRP A 1 552 ? -22.501 54.984 -7.525 1.00 21.14 ? 605 TRP A CE3 1 ATOM 4428 C CZ2 . TRP A 1 552 ? -22.792 53.570 -5.095 1.00 20.85 ? 605 TRP A CZ2 1 ATOM 4429 C CZ3 . TRP A 1 552 ? -22.510 55.641 -6.302 1.00 20.85 ? 605 TRP A CZ3 1 ATOM 4430 C CH2 . TRP A 1 552 ? -22.668 54.932 -5.102 1.00 22.13 ? 605 TRP A CH2 1 ATOM 4431 N N . TRP A 1 553 ? -19.241 54.243 -10.101 1.00 28.79 ? 606 TRP A N 1 ATOM 4432 C CA . TRP A 1 553 ? -18.463 55.421 -9.777 1.00 31.23 ? 606 TRP A CA 1 ATOM 4433 C C . TRP A 1 553 ? -17.644 55.839 -10.989 1.00 32.88 ? 606 TRP A C 1 ATOM 4434 O O . TRP A 1 553 ? -17.220 54.990 -11.771 1.00 33.37 ? 606 TRP A O 1 ATOM 4435 C CB . TRP A 1 553 ? -17.542 55.100 -8.594 1.00 31.62 ? 606 TRP A CB 1 ATOM 4436 C CG . TRP A 1 553 ? -18.291 54.915 -7.316 1.00 29.77 ? 606 TRP A CG 1 ATOM 4437 C CD1 . TRP A 1 553 ? -19.071 53.854 -6.960 1.00 30.17 ? 606 TRP A CD1 1 ATOM 4438 C CD2 . TRP A 1 553 ? -18.352 55.836 -6.224 1.00 29.31 ? 606 TRP A CD2 1 ATOM 4439 N NE1 . TRP A 1 553 ? -19.603 54.057 -5.707 1.00 29.71 ? 606 TRP A NE1 1 ATOM 4440 C CE2 . TRP A 1 553 ? -19.174 55.268 -5.236 1.00 27.61 ? 606 TRP A CE2 1 ATOM 4441 C CE3 . TRP A 1 553 ? -17.781 57.081 -5.975 1.00 27.15 ? 606 TRP A CE3 1 ATOM 4442 C CZ2 . TRP A 1 553 ? -19.437 55.902 -4.039 1.00 28.81 ? 606 TRP A CZ2 1 ATOM 4443 C CZ3 . TRP A 1 553 ? -18.042 57.702 -4.782 1.00 26.54 ? 606 TRP A CZ3 1 ATOM 4444 C CH2 . TRP A 1 553 ? -18.861 57.118 -3.832 1.00 27.03 ? 606 TRP A CH2 1 ATOM 4445 N N . THR A 1 554 ? -17.421 57.140 -11.143 1.00 34.63 ? 607 THR A N 1 ATOM 4446 C CA . THR A 1 554 ? -16.361 57.624 -12.020 1.00 35.25 ? 607 THR A CA 1 ATOM 4447 C C . THR A 1 554 ? -15.019 57.478 -11.350 1.00 37.10 ? 607 THR A C 1 ATOM 4448 O O . THR A 1 554 ? -14.900 57.608 -10.127 1.00 37.91 ? 607 THR A O 1 ATOM 4449 C CB . THR A 1 554 ? -16.552 59.108 -12.375 1.00 35.91 ? 607 THR A CB 1 ATOM 4450 O OG1 . THR A 1 554 ? -16.255 59.927 -11.231 1.00 33.39 ? 607 THR A OG1 1 ATOM 4451 C CG2 . THR A 1 554 ? -18.000 59.415 -12.706 1.00 36.91 ? 607 THR A CG2 1 ATOM 4452 N N . GLN A 1 555 ? -13.999 57.247 -12.167 1.00 37.18 ? 608 GLN A N 1 ATOM 4453 C CA . GLN A 1 555 ? -12.643 57.147 -11.671 1.00 36.41 ? 608 GLN A CA 1 ATOM 4454 C C . GLN A 1 555 ? -12.309 58.313 -10.740 1.00 34.23 ? 608 GLN A C 1 ATOM 4455 O O . GLN A 1 555 ? -11.698 58.121 -9.688 1.00 35.03 ? 608 GLN A O 1 ATOM 4456 C CB . GLN A 1 555 ? -11.667 57.077 -12.841 1.00 38.75 ? 608 GLN A CB 1 ATOM 4457 C CG . GLN A 1 555 ? -11.653 55.721 -13.516 1.00 42.40 ? 608 GLN A CG 1 ATOM 4458 C CD . GLN A 1 555 ? -11.542 55.825 -15.023 1.00 45.83 ? 608 GLN A CD 1 ATOM 4459 O OE1 . GLN A 1 555 ? -10.654 56.510 -15.537 1.00 48.24 ? 608 GLN A OE1 1 ATOM 4460 N NE2 . GLN A 1 555 ? -12.442 55.146 -15.739 1.00 46.41 ? 608 GLN A NE2 1 ATOM 4461 N N . GLN A 1 556 ? -12.710 59.522 -11.110 1.00 32.13 ? 609 GLN A N 1 ATOM 4462 C CA . GLN A 1 556 ? -12.383 60.681 -10.284 1.00 31.42 ? 609 GLN A CA 1 ATOM 4463 C C . GLN A 1 556 ? -13.064 60.582 -8.918 1.00 30.65 ? 609 GLN A C 1 ATOM 4464 O O . GLN A 1 556 ? -12.436 60.785 -7.880 1.00 32.94 ? 609 GLN A O 1 ATOM 4465 C CB . GLN A 1 556 ? -12.794 61.981 -10.966 1.00 27.92 ? 609 GLN A CB 1 ATOM 4466 C CG . GLN A 1 556 ? -12.116 63.206 -10.371 1.00 29.28 ? 609 GLN A CG 1 ATOM 4467 C CD . GLN A 1 556 ? -10.600 63.091 -10.362 1.00 33.08 ? 609 GLN A CD 1 ATOM 4468 O OE1 . GLN A 1 556 ? -9.961 63.242 -9.306 1.00 33.25 ? 609 GLN A OE1 1 ATOM 4469 N NE2 . GLN A 1 556 ? -10.017 62.816 -11.531 1.00 31.27 ? 609 GLN A NE2 1 ATOM 4470 N N . SER A 1 557 ? -14.356 60.290 -8.927 1.00 29.34 ? 610 SER A N 1 ATOM 4471 C CA . SER A 1 557 ? -15.122 60.256 -7.696 1.00 31.75 ? 610 SER A CA 1 ATOM 4472 C C . SER A 1 557 ? -14.652 59.112 -6.807 1.00 31.21 ? 610 SER A C 1 ATOM 4473 O O . SER A 1 557 ? -14.484 59.289 -5.608 1.00 32.88 ? 610 SER A O 1 ATOM 4474 C CB . SER A 1 557 ? -16.608 60.132 -8.007 1.00 31.85 ? 610 SER A CB 1 ATOM 4475 O OG . SER A 1 557 ? -17.125 61.408 -8.337 1.00 34.33 ? 610 SER A OG 1 ATOM 4476 N N . ALA A 1 558 ? -14.392 57.958 -7.412 1.00 30.71 ? 611 ALA A N 1 ATOM 4477 C CA . ALA A 1 558 ? -13.844 56.813 -6.693 1.00 31.38 ? 611 ALA A CA 1 ATOM 4478 C C . ALA A 1 558 ? -12.517 57.136 -6.026 1.00 32.34 ? 611 ALA A C 1 ATOM 4479 O O . ALA A 1 558 ? -12.261 56.730 -4.890 1.00 29.03 ? 611 ALA A O 1 ATOM 4480 C CB . ALA A 1 558 ? -13.670 55.636 -7.639 1.00 31.18 ? 611 ALA A CB 1 ATOM 4481 N N . SER A 1 559 ? -11.666 57.860 -6.744 1.00 33.50 ? 612 SER A N 1 ATOM 4482 C CA . SER A 1 559 ? -10.335 58.180 -6.247 1.00 29.88 ? 612 SER A CA 1 ATOM 4483 C C . SER A 1 559 ? -10.401 59.195 -5.120 1.00 27.62 ? 612 SER A C 1 ATOM 4484 O O . SER A 1 559 ? -9.562 59.196 -4.232 1.00 30.34 ? 612 SER A O 1 ATOM 4485 C CB . SER A 1 559 ? -9.461 58.731 -7.378 1.00 29.30 ? 612 SER A CB 1 ATOM 4486 O OG . SER A 1 559 ? -8.616 59.766 -6.898 1.00 29.26 ? 612 SER A OG 1 ATOM 4487 N N . ASN A 1 560 ? -11.389 60.077 -5.170 1.00 28.96 ? 613 ASN A N 1 ATOM 4488 C CA . ASN A 1 560 ? -11.583 61.061 -4.112 1.00 26.94 ? 613 ASN A CA 1 ATOM 4489 C C . ASN A 1 560 ? -12.100 60.420 -2.813 1.00 26.52 ? 613 ASN A C 1 ATOM 4490 O O . ASN A 1 560 ? -11.671 60.786 -1.704 1.00 22.36 ? 613 ASN A O 1 ATOM 4491 C CB . ASN A 1 560 ? -12.570 62.125 -4.583 1.00 29.05 ? 613 ASN A CB 1 ATOM 4492 C CG . ASN A 1 560 ? -12.040 62.943 -5.754 1.00 30.21 ? 613 ASN A CG 1 ATOM 4493 O OD1 . ASN A 1 560 ? -10.835 62.948 -6.029 1.00 29.62 ? 613 ASN A OD1 1 ATOM 4494 N ND2 . ASN A 1 560 ? -12.941 63.656 -6.439 1.00 27.95 ? 613 ASN A ND2 1 ATOM 4495 N N . PHE A 1 561 ? -13.025 59.473 -2.965 1.00 24.10 ? 614 PHE A N 1 ATOM 4496 C CA . PHE A 1 561 ? -13.479 58.638 -1.855 1.00 25.85 ? 614 PHE A CA 1 ATOM 4497 C C . PHE A 1 561 ? -12.274 58.050 -1.131 1.00 25.85 ? 614 PHE A C 1 ATOM 4498 O O . PHE A 1 561 ? -12.086 58.260 0.069 1.00 21.25 ? 614 PHE A O 1 ATOM 4499 C CB . PHE A 1 561 ? -14.391 57.509 -2.358 1.00 24.57 ? 614 PHE A CB 1 ATOM 4500 C CG . PHE A 1 561 ? -14.925 56.626 -1.265 1.00 26.38 ? 614 PHE A CG 1 ATOM 4501 C CD1 . PHE A 1 561 ? -14.222 55.497 -0.858 1.00 28.21 ? 614 PHE A CD1 1 ATOM 4502 C CD2 . PHE A 1 561 ? -16.127 56.918 -0.647 1.00 27.69 ? 614 PHE A CD2 1 ATOM 4503 C CE1 . PHE A 1 561 ? -14.706 54.682 0.146 1.00 29.37 ? 614 PHE A CE1 1 ATOM 4504 C CE2 . PHE A 1 561 ? -16.620 56.111 0.361 1.00 29.83 ? 614 PHE A CE2 1 ATOM 4505 C CZ . PHE A 1 561 ? -15.909 54.987 0.759 1.00 31.16 ? 614 PHE A CZ 1 ATOM 4506 N N . LYS A 1 562 ? -11.441 57.335 -1.875 1.00 28.67 ? 615 LYS A N 1 ATOM 4507 C CA . LYS A 1 562 ? -10.211 56.805 -1.307 1.00 31.14 ? 615 LYS A CA 1 ATOM 4508 C C . LYS A 1 562 ? -9.433 57.908 -0.617 1.00 31.40 ? 615 LYS A C 1 ATOM 4509 O O . LYS A 1 562 ? -8.882 57.705 0.463 1.00 35.57 ? 615 LYS A O 1 ATOM 4510 C CB . LYS A 1 562 ? -9.356 56.146 -2.383 1.00 31.10 ? 615 LYS A CB 1 ATOM 4511 C CG . LYS A 1 562 ? -9.824 54.749 -2.739 1.00 30.58 ? 615 LYS A CG 1 ATOM 4512 C CD . LYS A 1 562 ? -9.843 54.541 -4.227 1.00 29.18 ? 615 LYS A CD 1 ATOM 4513 C CE . LYS A 1 562 ? -9.664 53.089 -4.588 1.00 30.04 ? 615 LYS A CE 1 ATOM 4514 N NZ . LYS A 1 562 ? -8.728 52.930 -5.732 1.00 33.23 ? 615 LYS A NZ 1 ATOM 4515 N N . GLU A 1 563 ? -9.396 59.086 -1.219 1.00 30.34 ? 616 GLU A N 1 ATOM 4516 C CA . GLU A 1 563 ? -8.590 60.142 -0.645 1.00 31.54 ? 616 GLU A CA 1 ATOM 4517 C C . GLU A 1 563 ? -9.250 60.683 0.615 1.00 29.69 ? 616 GLU A C 1 ATOM 4518 O O . GLU A 1 563 ? -8.597 60.839 1.649 1.00 27.98 ? 616 GLU A O 1 ATOM 4519 C CB . GLU A 1 563 ? -8.348 61.278 -1.635 1.00 34.45 ? 616 GLU A CB 1 ATOM 4520 C CG . GLU A 1 563 ? -7.603 62.441 -1.005 1.00 38.24 ? 616 GLU A CG 1 ATOM 4521 C CD . GLU A 1 563 ? -7.370 63.591 -1.959 1.00 43.75 ? 616 GLU A CD 1 ATOM 4522 O OE1 . GLU A 1 563 ? -7.634 64.748 -1.548 1.00 45.55 ? 616 GLU A OE1 1 ATOM 4523 O OE2 . GLU A 1 563 ? -6.920 63.339 -3.112 1.00 46.54 ? 616 GLU A OE2 1 ATOM 4524 N N . GLN A 1 564 ? -10.541 60.983 0.527 1.00 28.18 ? 617 GLN A N 1 ATOM 4525 C CA . GLN A 1 564 ? -11.275 61.458 1.693 1.00 28.18 ? 617 GLN A CA 1 ATOM 4526 C C . GLN A 1 564 ? -11.242 60.404 2.801 1.00 25.92 ? 617 GLN A C 1 ATOM 4527 O O . GLN A 1 564 ? -11.053 60.732 3.959 1.00 26.02 ? 617 GLN A O 1 ATOM 4528 C CB . GLN A 1 564 ? -12.727 61.781 1.336 1.00 30.34 ? 617 GLN A CB 1 ATOM 4529 C CG . GLN A 1 564 ? -12.896 62.781 0.213 1.00 31.06 ? 617 GLN A CG 1 ATOM 4530 C CD . GLN A 1 564 ? -12.495 64.183 0.622 1.00 30.90 ? 617 GLN A CD 1 ATOM 4531 O OE1 . GLN A 1 564 ? -11.920 64.926 -0.175 1.00 31.30 ? 617 GLN A OE1 1 ATOM 4532 N NE2 . GLN A 1 564 ? -12.794 64.550 1.863 1.00 29.69 ? 617 GLN A NE2 1 ATOM 4533 N N . SER A 1 565 ? -11.427 59.140 2.446 1.00 26.22 ? 618 SER A N 1 ATOM 4534 C CA . SER A 1 565 ? -11.511 58.100 3.467 1.00 26.14 ? 618 SER A CA 1 ATOM 4535 C C . SER A 1 565 ? -10.129 57.858 4.077 1.00 29.04 ? 618 SER A C 1 ATOM 4536 O O . SER A 1 565 ? -10.007 57.503 5.248 1.00 26.22 ? 618 SER A O 1 ATOM 4537 C CB . SER A 1 565 ? -12.106 56.802 2.904 1.00 24.07 ? 618 SER A CB 1 ATOM 4538 O OG . SER A 1 565 ? -11.334 56.290 1.831 1.00 28.63 ? 618 SER A OG 1 ATOM 4539 N N . GLN A 1 566 ? -9.087 58.100 3.291 1.00 30.96 ? 619 GLN A N 1 ATOM 4540 C CA . GLN A 1 566 ? -7.719 58.003 3.792 1.00 32.14 ? 619 GLN A CA 1 ATOM 4541 C C . GLN A 1 566 ? -7.514 58.806 5.076 1.00 29.61 ? 619 GLN A C 1 ATOM 4542 O O . GLN A 1 566 ? -6.726 58.432 5.934 1.00 29.79 ? 619 GLN A O 1 ATOM 4543 C CB . GLN A 1 566 ? -6.720 58.465 2.723 1.00 32.86 ? 619 GLN A CB 1 ATOM 4544 C CG . GLN A 1 566 ? -5.358 57.783 2.832 1.00 34.06 ? 619 GLN A CG 1 ATOM 4545 C CD . GLN A 1 566 ? -5.466 56.261 2.787 1.00 36.98 ? 619 GLN A CD 1 ATOM 4546 O OE1 . GLN A 1 566 ? -4.652 55.561 3.378 1.00 37.59 ? 619 GLN A OE1 1 ATOM 4547 N NE2 . GLN A 1 566 ? -6.482 55.756 2.092 1.00 39.75 ? 619 GLN A NE2 1 ATOM 4548 N N . CYS A 1 567 ? -8.221 59.918 5.205 1.00 30.08 ? 620 CYS A N 1 ATOM 4549 C CA . CYS A 1 567 ? -8.101 60.745 6.390 1.00 29.19 ? 620 CYS A CA 1 ATOM 4550 C C . CYS A 1 567 ? -8.495 59.962 7.649 1.00 29.90 ? 620 CYS A C 1 ATOM 4551 O O . CYS A 1 567 ? -7.925 60.168 8.711 1.00 33.14 ? 620 CYS A O 1 ATOM 4552 C CB . CYS A 1 567 ? -8.971 61.985 6.231 1.00 29.77 ? 620 CYS A CB 1 ATOM 4553 S SG . CYS A 1 567 ? -8.907 63.125 7.619 1.00 31.26 ? 620 CYS A SG 1 ATOM 4554 N N . MET A 1 568 ? -9.462 59.057 7.523 1.00 25.80 ? 621 MET A N 1 ATOM 4555 C CA . MET A 1 568 ? -9.926 58.267 8.662 1.00 24.12 ? 621 MET A CA 1 ATOM 4556 C C . MET A 1 568 ? -9.005 57.084 8.932 1.00 22.89 ? 621 MET A C 1 ATOM 4557 O O . MET A 1 568 ? -8.822 56.669 10.071 1.00 19.43 ? 621 MET A O 1 ATOM 4558 C CB . MET A 1 568 ? -11.361 57.783 8.427 1.00 23.10 ? 621 MET A CB 1 ATOM 4559 C CG . MET A 1 568 ? -12.402 58.889 8.580 1.00 21.68 ? 621 MET A CG 1 ATOM 4560 S SD . MET A 1 568 ? -14.047 58.412 8.053 1.00 24.58 ? 621 MET A SD 1 ATOM 4561 C CE . MET A 1 568 ? -14.916 59.954 8.294 1.00 25.27 ? 621 MET A CE 1 ATOM 4562 N N . VAL A 1 569 ? -8.401 56.553 7.883 1.00 24.63 ? 622 VAL A N 1 ATOM 4563 C CA . VAL A 1 569 ? -7.364 55.557 8.066 1.00 26.27 ? 622 VAL A CA 1 ATOM 4564 C C . VAL A 1 569 ? -6.272 56.114 8.977 1.00 27.77 ? 622 VAL A C 1 ATOM 4565 O O . VAL A 1 569 ? -5.897 55.471 9.954 1.00 31.27 ? 622 VAL A O 1 ATOM 4566 C CB . VAL A 1 569 ? -6.801 55.075 6.718 1.00 26.93 ? 622 VAL A CB 1 ATOM 4567 C CG1 . VAL A 1 569 ? -5.674 54.067 6.926 1.00 25.78 ? 622 VAL A CG1 1 ATOM 4568 C CG2 . VAL A 1 569 ? -7.914 54.444 5.887 1.00 26.99 ? 622 VAL A CG2 1 ATOM 4569 N N . TYR A 1 570 ? -5.787 57.317 8.686 1.00 26.55 ? 623 TYR A N 1 ATOM 4570 C CA . TYR A 1 570 ? -4.740 57.935 9.505 1.00 27.08 ? 623 TYR A CA 1 ATOM 4571 C C . TYR A 1 570 ? -5.204 58.308 10.927 1.00 22.99 ? 623 TYR A C 1 ATOM 4572 O O . TYR A 1 570 ? -4.553 57.944 11.910 1.00 23.76 ? 623 TYR A O 1 ATOM 4573 C CB . TYR A 1 570 ? -4.169 59.177 8.807 1.00 28.88 ? 623 TYR A CB 1 ATOM 4574 C CG . TYR A 1 570 ? -3.353 58.872 7.572 1.00 31.48 ? 623 TYR A CG 1 ATOM 4575 C CD1 . TYR A 1 570 ? -2.664 57.669 7.450 1.00 30.42 ? 623 TYR A CD1 1 ATOM 4576 C CD2 . TYR A 1 570 ? -3.267 59.788 6.524 1.00 32.89 ? 623 TYR A CD2 1 ATOM 4577 C CE1 . TYR A 1 570 ? -1.911 57.386 6.326 1.00 31.60 ? 623 TYR A CE1 1 ATOM 4578 C CE2 . TYR A 1 570 ? -2.509 59.509 5.387 1.00 33.85 ? 623 TYR A CE2 1 ATOM 4579 C CZ . TYR A 1 570 ? -1.835 58.307 5.297 1.00 33.40 ? 623 TYR A CZ 1 ATOM 4580 O OH . TYR A 1 570 ? -1.088 58.018 4.175 1.00 33.80 ? 623 TYR A OH 1 ATOM 4581 N N . GLN A 1 571 ? -6.316 59.031 11.035 1.00 20.51 ? 624 GLN A N 1 ATOM 4582 C CA . GLN A 1 571 ? -6.804 59.503 12.340 1.00 20.87 ? 624 GLN A CA 1 ATOM 4583 C C . GLN A 1 571 ? -6.939 58.359 13.326 1.00 21.27 ? 624 GLN A C 1 ATOM 4584 O O . GLN A 1 571 ? -6.480 58.460 14.468 1.00 27.74 ? 624 GLN A O 1 ATOM 4585 C CB . GLN A 1 571 ? -8.157 60.210 12.201 1.00 20.32 ? 624 GLN A CB 1 ATOM 4586 C CG . GLN A 1 571 ? -8.865 60.492 13.532 1.00 17.88 ? 624 GLN A CG 1 ATOM 4587 C CD . GLN A 1 571 ? -10.332 60.879 13.348 1.00 17.22 ? 624 GLN A CD 1 ATOM 4588 O OE1 . GLN A 1 571 ? -10.934 60.600 12.309 1.00 18.34 ? 624 GLN A OE1 1 ATOM 4589 N NE2 . GLN A 1 571 ? -10.900 61.512 14.348 1.00 14.15 ? 624 GLN A NE2 1 ATOM 4590 N N . TYR A 1 572 ? -7.562 57.268 12.889 1.00 19.53 ? 625 TYR A N 1 ATOM 4591 C CA . TYR A 1 572 ? -7.827 56.148 13.778 1.00 20.24 ? 625 TYR A CA 1 ATOM 4592 C C . TYR A 1 572 ? -6.626 55.213 13.901 1.00 20.70 ? 625 TYR A C 1 ATOM 4593 O O . TYR A 1 572 ? -6.361 54.655 14.967 1.00 21.08 ? 625 TYR A O 1 ATOM 4594 C CB . TYR A 1 572 ? -9.018 55.339 13.279 1.00 20.07 ? 625 TYR A CB 1 ATOM 4595 C CG . TYR A 1 572 ? -10.368 55.962 13.519 1.00 19.45 ? 625 TYR A CG 1 ATOM 4596 C CD1 . TYR A 1 572 ? -10.841 56.968 12.687 1.00 19.23 ? 625 TYR A CD1 1 ATOM 4597 C CD2 . TYR A 1 572 ? -11.196 55.515 14.548 1.00 19.66 ? 625 TYR A CD2 1 ATOM 4598 C CE1 . TYR A 1 572 ? -12.096 57.523 12.876 1.00 19.13 ? 625 TYR A CE1 1 ATOM 4599 C CE2 . TYR A 1 572 ? -12.445 56.072 14.750 1.00 18.23 ? 625 TYR A CE2 1 ATOM 4600 C CZ . TYR A 1 572 ? -12.890 57.083 13.905 1.00 19.49 ? 625 TYR A CZ 1 ATOM 4601 O OH . TYR A 1 572 ? -14.134 57.658 14.075 1.00 17.53 ? 625 TYR A OH 1 ATOM 4602 N N . GLY A 1 573 ? -5.912 55.037 12.800 1.00 23.26 ? 626 GLY A N 1 ATOM 4603 C CA . GLY A 1 573 ? -4.623 54.375 12.817 1.00 22.72 ? 626 GLY A CA 1 ATOM 4604 C C . GLY A 1 573 ? -3.739 54.887 13.925 1.00 25.21 ? 626 GLY A C 1 ATOM 4605 O O . GLY A 1 573 ? -2.871 54.165 14.400 1.00 25.76 ? 626 GLY A O 1 ATOM 4606 N N . ASN A 1 574 ? -3.963 56.130 14.344 1.00 25.63 ? 627 ASN A N 1 ATOM 4607 C CA . ASN A 1 574 ? -3.014 56.811 15.211 1.00 27.51 ? 627 ASN A CA 1 ATOM 4608 C C . ASN A 1 574 ? -3.338 56.716 16.698 1.00 28.37 ? 627 ASN A C 1 ATOM 4609 O O . ASN A 1 574 ? -2.442 56.888 17.531 1.00 24.96 ? 627 ASN A O 1 ATOM 4610 C CB . ASN A 1 574 ? -2.895 58.284 14.817 1.00 31.43 ? 627 ASN A CB 1 ATOM 4611 C CG . ASN A 1 574 ? -1.754 58.528 13.867 1.00 33.79 ? 627 ASN A CG 1 ATOM 4612 O OD1 . ASN A 1 574 ? -0.644 58.841 14.285 1.00 35.20 ? 627 ASN A OD1 1 ATOM 4613 N ND2 . ASN A 1 574 ? -2.012 58.364 12.579 1.00 36.80 ? 627 ASN A ND2 1 ATOM 4614 N N . PHE A 1 575 ? -4.596 56.441 17.037 1.00 25.52 ? 628 PHE A N 1 ATOM 4615 C CA . PHE A 1 575 ? -4.935 56.118 18.416 1.00 25.92 ? 628 PHE A CA 1 ATOM 4616 C C . PHE A 1 575 ? -4.111 54.924 18.860 1.00 26.30 ? 628 PHE A C 1 ATOM 4617 O O . PHE A 1 575 ? -3.978 53.941 18.135 1.00 27.72 ? 628 PHE A O 1 ATOM 4618 C CB . PHE A 1 575 ? -6.410 55.748 18.564 1.00 24.91 ? 628 PHE A CB 1 ATOM 4619 C CG . PHE A 1 575 ? -7.361 56.829 18.168 1.00 22.78 ? 628 PHE A CG 1 ATOM 4620 C CD1 . PHE A 1 575 ? -7.258 58.106 18.685 1.00 22.39 ? 628 PHE A CD1 1 ATOM 4621 C CD2 . PHE A 1 575 ? -8.383 56.549 17.287 1.00 24.22 ? 628 PHE A CD2 1 ATOM 4622 C CE1 . PHE A 1 575 ? -8.165 59.092 18.313 1.00 23.60 ? 628 PHE A CE1 1 ATOM 4623 C CE2 . PHE A 1 575 ? -9.298 57.522 16.917 1.00 24.71 ? 628 PHE A CE2 1 ATOM 4624 C CZ . PHE A 1 575 ? -9.192 58.794 17.428 1.00 23.58 ? 628 PHE A CZ 1 ATOM 4625 N N . SER A 1 576 ? -3.579 54.994 20.069 1.00 27.83 ? 629 SER A N 1 ATOM 4626 C CA . SER A 1 576 ? -3.024 53.811 20.682 1.00 27.84 ? 629 SER A CA 1 ATOM 4627 C C . SER A 1 576 ? -3.874 53.413 21.871 1.00 25.04 ? 629 SER A C 1 ATOM 4628 O O . SER A 1 576 ? -4.402 54.258 22.581 1.00 27.39 ? 629 SER A O 1 ATOM 4629 C CB . SER A 1 576 ? -1.580 54.061 21.102 1.00 29.10 ? 629 SER A CB 1 ATOM 4630 O OG . SER A 1 576 ? -1.500 55.229 21.889 1.00 33.26 ? 629 SER A OG 1 ATOM 4631 N N . TRP A 1 577 ? -4.011 52.116 22.076 1.00 22.07 ? 630 TRP A N 1 ATOM 4632 C CA . TRP A 1 577 ? -5.055 51.595 22.935 1.00 20.95 ? 630 TRP A CA 1 ATOM 4633 C C . TRP A 1 577 ? -4.442 50.946 24.168 1.00 20.96 ? 630 TRP A C 1 ATOM 4634 O O . TRP A 1 577 ? -3.796 49.905 24.079 1.00 20.46 ? 630 TRP A O 1 ATOM 4635 C CB . TRP A 1 577 ? -5.885 50.569 22.169 1.00 19.41 ? 630 TRP A CB 1 ATOM 4636 C CG . TRP A 1 577 ? -7.094 50.160 22.893 1.00 20.14 ? 630 TRP A CG 1 ATOM 4637 C CD1 . TRP A 1 577 ? -7.615 50.739 24.014 1.00 17.88 ? 630 TRP A CD1 1 ATOM 4638 C CD2 . TRP A 1 577 ? -7.962 49.079 22.560 1.00 19.08 ? 630 TRP A CD2 1 ATOM 4639 N NE1 . TRP A 1 577 ? -8.761 50.084 24.388 1.00 17.28 ? 630 TRP A NE1 1 ATOM 4640 C CE2 . TRP A 1 577 ? -8.987 49.054 23.513 1.00 17.70 ? 630 TRP A CE2 1 ATOM 4641 C CE3 . TRP A 1 577 ? -7.979 48.125 21.540 1.00 19.91 ? 630 TRP A CE3 1 ATOM 4642 C CZ2 . TRP A 1 577 ? -9.999 48.118 23.483 1.00 15.58 ? 630 TRP A CZ2 1 ATOM 4643 C CZ3 . TRP A 1 577 ? -8.976 47.199 21.522 1.00 17.34 ? 630 TRP A CZ3 1 ATOM 4644 C CH2 . TRP A 1 577 ? -9.971 47.198 22.479 1.00 17.88 ? 630 TRP A CH2 1 ATOM 4645 N N . ASP A 1 578 ? -4.643 51.559 25.325 1.00 24.03 ? 631 ASP A N 1 ATOM 4646 C CA . ASP A 1 578 ? -3.928 51.128 26.506 1.00 26.09 ? 631 ASP A CA 1 ATOM 4647 C C . ASP A 1 578 ? -4.203 49.651 26.718 1.00 24.67 ? 631 ASP A C 1 ATOM 4648 O O . ASP A 1 578 ? -3.283 48.855 26.850 1.00 25.70 ? 631 ASP A O 1 ATOM 4649 C CB . ASP A 1 578 ? -4.325 51.961 27.721 1.00 28.61 ? 631 ASP A CB 1 ATOM 4650 C CG . ASP A 1 578 ? -5.815 52.000 27.939 1.00 30.38 ? 631 ASP A CG 1 ATOM 4651 O OD1 . ASP A 1 578 ? -6.232 52.450 29.032 1.00 34.03 ? 631 ASP A OD1 1 ATOM 4652 O OD2 . ASP A 1 578 ? -6.641 51.596 27.090 1.00 26.94 ? 631 ASP A OD2 1 ATOM 4653 N N . LEU A 1 579 ? -5.474 49.279 26.700 1.00 24.13 ? 632 LEU A N 1 ATOM 4654 C CA . LEU A 1 579 ? -5.878 47.962 27.172 1.00 26.09 ? 632 LEU A CA 1 ATOM 4655 C C . LEU A 1 579 ? -5.237 46.870 26.320 1.00 25.58 ? 632 LEU A C 1 ATOM 4656 O O . LEU A 1 579 ? -4.975 45.761 26.796 1.00 22.79 ? 632 LEU A O 1 ATOM 4657 C CB . LEU A 1 579 ? -7.407 47.845 27.167 1.00 27.65 ? 632 LEU A CB 1 ATOM 4658 C CG . LEU A 1 579 ? -8.089 48.612 28.313 1.00 29.54 ? 632 LEU A CG 1 ATOM 4659 C CD1 . LEU A 1 579 ? -9.603 48.577 28.164 1.00 30.25 ? 632 LEU A CD1 1 ATOM 4660 C CD2 . LEU A 1 579 ? -7.673 48.058 29.680 1.00 28.62 ? 632 LEU A CD2 1 ATOM 4661 N N . ALA A 1 580 ? -4.963 47.201 25.062 1.00 24.07 ? 633 ALA A N 1 ATOM 4662 C CA . ALA A 1 580 ? -4.239 46.301 24.184 1.00 24.75 ? 633 ALA A CA 1 ATOM 4663 C C . ALA A 1 580 ? -2.734 46.532 24.294 1.00 25.74 ? 633 ALA A C 1 ATOM 4664 O O . ALA A 1 580 ? -1.979 46.140 23.409 1.00 21.86 ? 633 ALA A O 1 ATOM 4665 C CB . ALA A 1 580 ? -4.696 46.499 22.751 1.00 26.71 ? 633 ALA A CB 1 ATOM 4666 N N . GLY A 1 581 ? -2.306 47.173 25.381 1.00 26.24 ? 634 GLY A N 1 ATOM 4667 C CA . GLY A 1 581 ? -0.893 47.394 25.624 1.00 27.11 ? 634 GLY A CA 1 ATOM 4668 C C . GLY A 1 581 ? -0.242 48.421 24.699 1.00 26.73 ? 634 GLY A C 1 ATOM 4669 O O . GLY A 1 581 ? 0.935 48.307 24.368 1.00 26.54 ? 634 GLY A O 1 ATOM 4670 N N . GLY A 1 582 ? -0.998 49.429 24.284 1.00 24.80 ? 635 GLY A N 1 ATOM 4671 C CA . GLY A 1 582 ? -0.430 50.535 23.542 1.00 25.74 ? 635 GLY A CA 1 ATOM 4672 C C . GLY A 1 582 ? -0.371 50.359 22.027 1.00 26.19 ? 635 GLY A C 1 ATOM 4673 O O . GLY A 1 582 ? 0.050 51.271 21.319 1.00 25.36 ? 635 GLY A O 1 ATOM 4674 N N . GLN A 1 583 ? -0.803 49.214 21.513 1.00 25.16 ? 636 GLN A N 1 ATOM 4675 C CA . GLN A 1 583 ? -0.923 49.065 20.066 1.00 25.21 ? 636 GLN A CA 1 ATOM 4676 C C . GLN A 1 583 ? -1.854 50.116 19.439 1.00 26.44 ? 636 GLN A C 1 ATOM 4677 O O . GLN A 1 583 ? -2.834 50.570 20.042 1.00 24.61 ? 636 GLN A O 1 ATOM 4678 C CB . GLN A 1 583 ? -1.418 47.667 19.693 1.00 25.42 ? 636 GLN A CB 1 ATOM 4679 C CG . GLN A 1 583 ? -0.485 46.527 20.067 1.00 25.42 ? 636 GLN A CG 1 ATOM 4680 C CD . GLN A 1 583 ? -1.138 45.172 19.864 1.00 25.00 ? 636 GLN A CD 1 ATOM 4681 O OE1 . GLN A 1 583 ? -0.892 44.500 18.867 1.00 26.68 ? 636 GLN A OE1 1 ATOM 4682 N NE2 . GLN A 1 583 ? -1.984 44.777 20.805 1.00 24.07 ? 636 GLN A NE2 1 ATOM 4683 N N . HIS A 1 584 ? -1.530 50.484 18.208 1.00 27.43 ? 637 HIS A N 1 ATOM 4684 C CA . HIS A 1 584 ? -2.407 51.283 17.382 1.00 28.70 ? 637 HIS A CA 1 ATOM 4685 C C . HIS A 1 584 ? -3.558 50.419 16.870 1.00 24.15 ? 637 HIS A C 1 ATOM 4686 O O . HIS A 1 584 ? -3.399 49.223 16.630 1.00 20.83 ? 637 HIS A O 1 ATOM 4687 C CB . HIS A 1 584 ? -1.621 51.883 16.216 1.00 32.74 ? 637 HIS A CB 1 ATOM 4688 C CG . HIS A 1 584 ? -1.060 53.241 16.503 1.00 38.25 ? 637 HIS A CG 1 ATOM 4689 N ND1 . HIS A 1 584 ? 0.060 53.441 17.285 1.00 40.97 ? 637 HIS A ND1 1 ATOM 4690 C CD2 . HIS A 1 584 ? -1.472 54.471 16.115 1.00 42.09 ? 637 HIS A CD2 1 ATOM 4691 C CE1 . HIS A 1 584 ? 0.311 54.736 17.365 1.00 42.39 ? 637 HIS A CE1 1 ATOM 4692 N NE2 . HIS A 1 584 ? -0.605 55.382 16.666 1.00 43.64 ? 637 HIS A NE2 1 ATOM 4693 N N . LEU A 1 585 ? -4.724 51.027 16.714 1.00 23.08 ? 638 LEU A N 1 ATOM 4694 C CA . LEU A 1 585 ? -5.799 50.410 15.944 1.00 21.23 ? 638 LEU A CA 1 ATOM 4695 C C . LEU A 1 585 ? -5.361 50.223 14.503 1.00 20.92 ? 638 LEU A C 1 ATOM 4696 O O . LEU A 1 585 ? -4.567 50.996 13.993 1.00 18.24 ? 638 LEU A O 1 ATOM 4697 C CB . LEU A 1 585 ? -7.059 51.280 16.006 1.00 20.81 ? 638 LEU A CB 1 ATOM 4698 C CG . LEU A 1 585 ? -7.451 51.803 17.394 1.00 19.88 ? 638 LEU A CG 1 ATOM 4699 C CD1 . LEU A 1 585 ? -8.530 52.861 17.278 1.00 20.12 ? 638 LEU A CD1 1 ATOM 4700 C CD2 . LEU A 1 585 ? -7.879 50.676 18.332 1.00 19.09 ? 638 LEU A CD2 1 ATOM 4701 N N . ASN A 1 586 ? -5.874 49.186 13.851 1.00 21.48 ? 639 ASN A N 1 ATOM 4702 C CA . ASN A 1 586 ? -5.789 49.078 12.407 1.00 21.15 ? 639 ASN A CA 1 ATOM 4703 C C . ASN A 1 586 ? -6.779 49.997 11.703 1.00 22.77 ? 639 ASN A C 1 ATOM 4704 O O . ASN A 1 586 ? -7.987 49.759 11.749 1.00 17.11 ? 639 ASN A O 1 ATOM 4705 C CB . ASN A 1 586 ? -6.037 47.637 11.963 1.00 22.67 ? 639 ASN A CB 1 ATOM 4706 C CG . ASN A 1 586 ? -5.600 47.393 10.536 1.00 23.95 ? 639 ASN A CG 1 ATOM 4707 O OD1 . ASN A 1 586 ? -5.990 48.123 9.619 1.00 26.06 ? 639 ASN A OD1 1 ATOM 4708 N ND2 . ASN A 1 586 ? -4.778 46.377 10.338 1.00 25.81 ? 639 ASN A ND2 1 ATOM 4709 N N . GLY A 1 587 ? -6.253 51.030 11.038 1.00 24.30 ? 640 GLY A N 1 ATOM 4710 C CA . GLY A 1 587 ? -7.071 52.050 10.393 1.00 24.22 ? 640 GLY A CA 1 ATOM 4711 C C . GLY A 1 587 ? -7.806 51.538 9.163 1.00 24.46 ? 640 GLY A C 1 ATOM 4712 O O . GLY A 1 587 ? -8.894 52.018 8.809 1.00 26.26 ? 640 GLY A O 1 ATOM 4713 N N . ILE A 1 588 ? -7.221 50.550 8.505 1.00 24.88 ? 641 ILE A N 1 ATOM 4714 C CA . ILE A 1 588 ? -7.838 49.971 7.319 1.00 23.24 ? 641 ILE A CA 1 ATOM 4715 C C . ILE A 1 588 ? -8.988 49.018 7.672 1.00 20.43 ? 641 ILE A C 1 ATOM 4716 O O . ILE A 1 588 ? -10.068 49.121 7.119 1.00 15.05 ? 641 ILE A O 1 ATOM 4717 C CB . ILE A 1 588 ? -6.787 49.260 6.466 1.00 25.37 ? 641 ILE A CB 1 ATOM 4718 C CG1 . ILE A 1 588 ? -5.897 50.291 5.768 1.00 28.78 ? 641 ILE A CG1 1 ATOM 4719 C CG2 . ILE A 1 588 ? -7.470 48.370 5.419 1.00 25.89 ? 641 ILE A CG2 1 ATOM 4720 C CD1 . ILE A 1 588 ? -4.473 49.824 5.523 1.00 30.79 ? 641 ILE A CD1 1 ATOM 4721 N N . ASN A 1 589 ? -8.757 48.096 8.598 1.00 21.52 ? 642 ASN A N 1 ATOM 4722 C CA . ASN A 1 589 ? -9.766 47.096 8.936 1.00 21.71 ? 642 ASN A CA 1 ATOM 4723 C C . ASN A 1 589 ? -10.985 47.696 9.652 1.00 18.96 ? 642 ASN A C 1 ATOM 4724 O O . ASN A 1 589 ? -12.048 47.091 9.686 1.00 21.85 ? 642 ASN A O 1 ATOM 4725 C CB . ASN A 1 589 ? -9.147 45.992 9.789 1.00 22.48 ? 642 ASN A CB 1 ATOM 4726 C CG . ASN A 1 589 ? -8.013 45.280 9.081 1.00 26.14 ? 642 ASN A CG 1 ATOM 4727 O OD1 . ASN A 1 589 ? -7.913 45.324 7.856 1.00 28.65 ? 642 ASN A OD1 1 ATOM 4728 N ND2 . ASN A 1 589 ? -7.160 44.606 9.846 1.00 23.35 ? 642 ASN A ND2 1 ATOM 4729 N N . THR A 1 590 ? -10.837 48.887 10.211 1.00 15.92 ? 643 THR A N 1 ATOM 4730 C CA . THR A 1 590 ? -11.953 49.551 10.858 1.00 18.62 ? 643 THR A CA 1 ATOM 4731 C C . THR A 1 590 ? -12.608 50.582 9.957 1.00 17.74 ? 643 THR A C 1 ATOM 4732 O O . THR A 1 590 ? -13.639 51.160 10.318 1.00 17.25 ? 643 THR A O 1 ATOM 4733 C CB . THR A 1 590 ? -11.497 50.231 12.148 1.00 18.48 ? 643 THR A CB 1 ATOM 4734 O OG1 . THR A 1 590 ? -10.403 51.110 11.865 1.00 21.85 ? 643 THR A OG1 1 ATOM 4735 C CG2 . THR A 1 590 ? -10.929 49.224 13.111 1.00 19.65 ? 643 THR A CG2 1 ATOM 4736 N N . LEU A 1 591 ? -12.016 50.823 8.793 1.00 16.52 ? 644 LEU A N 1 ATOM 4737 C CA . LEU A 1 591 ? -12.373 52.008 8.025 1.00 19.05 ? 644 LEU A CA 1 ATOM 4738 C C . LEU A 1 591 ? -13.877 52.023 7.796 1.00 16.29 ? 644 LEU A C 1 ATOM 4739 O O . LEU A 1 591 ? -14.520 53.052 7.940 1.00 17.64 ? 644 LEU A O 1 ATOM 4740 C CB . LEU A 1 591 ? -11.639 52.051 6.677 1.00 17.93 ? 644 LEU A CB 1 ATOM 4741 C CG . LEU A 1 591 ? -12.008 53.288 5.853 1.00 19.34 ? 644 LEU A CG 1 ATOM 4742 C CD1 . LEU A 1 591 ? -11.526 54.523 6.541 1.00 19.37 ? 644 LEU A CD1 1 ATOM 4743 C CD2 . LEU A 1 591 ? -11.442 53.229 4.431 1.00 21.68 ? 644 LEU A CD2 1 ATOM 4744 N N . GLY A 1 592 ? -14.429 50.874 7.429 1.00 14.75 ? 645 GLY A N 1 ATOM 4745 C CA . GLY A 1 592 ? -15.814 50.808 7.007 1.00 15.31 ? 645 GLY A CA 1 ATOM 4746 C C . GLY A 1 592 ? -16.714 51.242 8.145 1.00 16.73 ? 645 GLY A C 1 ATOM 4747 O O . GLY A 1 592 ? -17.653 52.031 7.964 1.00 13.08 ? 645 GLY A O 1 ATOM 4748 N N . GLU A 1 593 ? -16.415 50.727 9.335 1.00 12.28 ? 646 GLU A N 1 ATOM 4749 C CA . GLU A 1 593 ? -17.208 51.050 10.507 1.00 16.50 ? 646 GLU A CA 1 ATOM 4750 C C . GLU A 1 593 ? -17.034 52.509 10.895 1.00 17.36 ? 646 GLU A C 1 ATOM 4751 O O . GLU A 1 593 ? -17.974 53.163 11.318 1.00 17.02 ? 646 GLU A O 1 ATOM 4752 C CB . GLU A 1 593 ? -16.834 50.130 11.668 1.00 14.45 ? 646 GLU A CB 1 ATOM 4753 C CG . GLU A 1 593 ? -17.245 48.692 11.418 1.00 14.09 ? 646 GLU A CG 1 ATOM 4754 C CD . GLU A 1 593 ? -18.754 48.512 11.256 1.00 12.99 ? 646 GLU A CD 1 ATOM 4755 O OE1 . GLU A 1 593 ? -19.544 49.336 11.755 1.00 16.08 ? 646 GLU A OE1 1 ATOM 4756 O OE2 . GLU A 1 593 ? -19.161 47.512 10.656 1.00 15.92 ? 646 GLU A OE2 1 ATOM 4757 N N . ASN A 1 594 ? -15.827 53.032 10.735 1.00 20.08 ? 647 ASN A N 1 ATOM 4758 C CA . ASN A 1 594 ? -15.591 54.417 11.079 1.00 17.20 ? 647 ASN A CA 1 ATOM 4759 C C . ASN A 1 594 ? -16.278 55.370 10.096 1.00 18.01 ? 647 ASN A C 1 ATOM 4760 O O . ASN A 1 594 ? -16.815 56.411 10.484 1.00 17.21 ? 647 ASN A O 1 ATOM 4761 C CB . ASN A 1 594 ? -14.094 54.672 11.171 1.00 17.08 ? 647 ASN A CB 1 ATOM 4762 C CG . ASN A 1 594 ? -13.447 53.923 12.327 1.00 16.55 ? 647 ASN A CG 1 ATOM 4763 O OD1 . ASN A 1 594 ? -14.096 53.640 13.328 1.00 17.12 ? 647 ASN A OD1 1 ATOM 4764 N ND2 . ASN A 1 594 ? -12.174 53.586 12.183 1.00 14.69 ? 647 ASN A ND2 1 ATOM 4765 N N . ILE A 1 595 ? -16.296 55.009 8.823 1.00 18.31 ? 648 ILE A N 1 ATOM 4766 C CA . ILE A 1 595 ? -17.008 55.824 7.850 1.00 17.78 ? 648 ILE A CA 1 ATOM 4767 C C . ILE A 1 595 ? -18.480 55.843 8.220 1.00 17.59 ? 648 ILE A C 1 ATOM 4768 O O . ILE A 1 595 ? -19.144 56.868 8.122 1.00 19.27 ? 648 ILE A O 1 ATOM 4769 C CB . ILE A 1 595 ? -16.816 55.271 6.424 1.00 17.27 ? 648 ILE A CB 1 ATOM 4770 C CG1 . ILE A 1 595 ? -15.432 55.626 5.893 1.00 17.85 ? 648 ILE A CG1 1 ATOM 4771 C CG2 . ILE A 1 595 ? -17.884 55.832 5.472 1.00 19.04 ? 648 ILE A CG2 1 ATOM 4772 C CD1 . ILE A 1 595 ? -14.906 54.628 4.866 1.00 15.03 ? 648 ILE A CD1 1 ATOM 4773 N N . ALA A 1 596 ? -18.991 54.690 8.641 1.00 19.20 ? 649 ALA A N 1 ATOM 4774 C CA . ALA A 1 596 ? -20.408 54.564 8.954 1.00 20.67 ? 649 ALA A CA 1 ATOM 4775 C C . ALA A 1 596 ? -20.783 55.337 10.214 1.00 19.85 ? 649 ALA A C 1 ATOM 4776 O O . ALA A 1 596 ? -21.890 55.853 10.307 1.00 18.14 ? 649 ALA A O 1 ATOM 4777 C CB . ALA A 1 596 ? -20.811 53.098 9.081 1.00 20.04 ? 649 ALA A CB 1 ATOM 4778 N N . ASP A 1 597 ? -19.863 55.434 11.169 1.00 18.58 ? 650 ASP A N 1 ATOM 4779 C CA . ASP A 1 597 ? -20.112 56.235 12.366 1.00 18.81 ? 650 ASP A CA 1 ATOM 4780 C C . ASP A 1 597 ? -20.143 57.735 12.102 1.00 19.97 ? 650 ASP A C 1 ATOM 4781 O O . ASP A 1 597 ? -21.028 58.441 12.585 1.00 18.16 ? 650 ASP A O 1 ATOM 4782 C CB . ASP A 1 597 ? -19.043 55.952 13.422 1.00 20.14 ? 650 ASP A CB 1 ATOM 4783 C CG . ASP A 1 597 ? -19.244 54.636 14.105 1.00 15.83 ? 650 ASP A CG 1 ATOM 4784 O OD1 . ASP A 1 597 ? -18.297 54.163 14.757 1.00 14.89 ? 650 ASP A OD1 1 ATOM 4785 O OD2 . ASP A 1 597 ? -20.312 54.002 14.026 1.00 14.57 ? 650 ASP A OD2 1 ATOM 4786 N N . ASN A 1 598 ? -19.152 58.227 11.362 1.00 20.16 ? 651 ASN A N 1 ATOM 4787 C CA . ASN A 1 598 ? -19.024 59.655 11.125 1.00 20.42 ? 651 ASN A CA 1 ATOM 4788 C C . ASN A 1 598 ? -20.144 60.181 10.212 1.00 20.93 ? 651 ASN A C 1 ATOM 4789 O O . ASN A 1 598 ? -20.732 61.226 10.476 1.00 21.12 ? 651 ASN A O 1 ATOM 4790 C CB . ASN A 1 598 ? -17.653 59.952 10.520 1.00 21.55 ? 651 ASN A CB 1 ATOM 4791 C CG . ASN A 1 598 ? -16.555 59.996 11.566 1.00 21.60 ? 651 ASN A CG 1 ATOM 4792 O OD1 . ASN A 1 598 ? -16.310 61.041 12.169 1.00 23.19 ? 651 ASN A OD1 1 ATOM 4793 N ND2 . ASN A 1 598 ? -15.886 58.859 11.789 1.00 18.43 ? 651 ASN A ND2 1 ATOM 4794 N N . GLY A 1 599 ? -20.460 59.448 9.151 1.00 21.19 ? 652 GLY A N 1 ATOM 4795 C CA . GLY A 1 599 ? -21.596 59.805 8.310 1.00 21.55 ? 652 GLY A CA 1 ATOM 4796 C C . GLY A 1 599 ? -22.915 59.686 9.048 1.00 23.34 ? 652 GLY A C 1 ATOM 4797 O O . GLY A 1 599 ? -23.808 60.540 8.941 1.00 22.36 ? 652 GLY A O 1 ATOM 4798 N N . GLY A 1 600 ? -23.035 58.613 9.816 1.00 23.54 ? 653 GLY A N 1 ATOM 4799 C CA . GLY A 1 600 ? -24.292 58.271 10.440 1.00 23.79 ? 653 GLY A CA 1 ATOM 4800 C C . GLY A 1 600 ? -24.669 59.259 11.514 1.00 21.61 ? 653 GLY A C 1 ATOM 4801 O O . GLY A 1 600 ? -25.833 59.594 11.661 1.00 21.81 ? 653 GLY A O 1 ATOM 4802 N N . LEU A 1 601 ? -23.683 59.726 12.269 1.00 22.60 ? 654 LEU A N 1 ATOM 4803 C CA . LEU A 1 601 ? -23.934 60.717 13.308 1.00 21.72 ? 654 LEU A CA 1 ATOM 4804 C C . LEU A 1 601 ? -24.323 62.068 12.727 1.00 22.28 ? 654 LEU A C 1 ATOM 4805 O O . LEU A 1 601 ? -25.215 62.727 13.230 1.00 23.10 ? 654 LEU A O 1 ATOM 4806 C CB . LEU A 1 601 ? -22.706 60.899 14.187 1.00 21.69 ? 654 LEU A CB 1 ATOM 4807 C CG . LEU A 1 601 ? -23.025 61.735 15.421 1.00 23.05 ? 654 LEU A CG 1 ATOM 4808 C CD1 . LEU A 1 601 ? -23.876 60.933 16.397 1.00 24.92 ? 654 LEU A CD1 1 ATOM 4809 C CD2 . LEU A 1 601 ? -21.779 62.194 16.072 1.00 25.89 ? 654 LEU A CD2 1 ATOM 4810 N N . GLY A 1 602 ? -23.629 62.491 11.680 1.00 23.72 ? 655 GLY A N 1 ATOM 4811 C CA . GLY A 1 602 ? -23.931 63.755 11.050 1.00 22.88 ? 655 GLY A CA 1 ATOM 4812 C C . GLY A 1 602 ? -25.309 63.752 10.418 1.00 21.72 ? 655 GLY A C 1 ATOM 4813 O O . GLY A 1 602 ? -26.061 64.697 10.576 1.00 21.73 ? 655 GLY A O 1 ATOM 4814 N N . GLN A 1 603 ? -25.629 62.685 9.698 1.00 21.67 ? 656 GLN A N 1 ATOM 4815 C CA . GLN A 1 603 ? -26.972 62.470 9.194 1.00 19.11 ? 656 GLN A CA 1 ATOM 4816 C C . GLN A 1 603 ? -28.018 62.676 10.274 1.00 20.76 ? 656 GLN A C 1 ATOM 4817 O O . GLN A 1 603 ? -29.051 63.297 10.044 1.00 23.91 ? 656 GLN A O 1 ATOM 4818 C CB . GLN A 1 603 ? -27.103 61.055 8.636 1.00 20.06 ? 656 GLN A CB 1 ATOM 4819 C CG . GLN A 1 603 ? -26.653 60.914 7.199 1.00 20.58 ? 656 GLN A CG 1 ATOM 4820 C CD . GLN A 1 603 ? -25.787 59.695 6.977 1.00 20.32 ? 656 GLN A CD 1 ATOM 4821 O OE1 . GLN A 1 603 ? -24.852 59.724 6.167 1.00 21.99 ? 656 GLN A OE1 1 ATOM 4822 N NE2 . GLN A 1 603 ? -26.102 58.614 7.674 1.00 15.20 ? 656 GLN A NE2 1 ATOM 4823 N N . ALA A 1 604 ? -27.774 62.123 11.453 1.00 21.08 ? 657 ALA A N 1 ATOM 4824 C CA . ALA A 1 604 ? -28.832 62.006 12.435 1.00 18.02 ? 657 ALA A CA 1 ATOM 4825 C C . ALA A 1 604 ? -29.036 63.353 13.107 1.00 19.25 ? 657 ALA A C 1 ATOM 4826 O O . ALA A 1 604 ? -30.158 63.720 13.454 1.00 19.84 ? 657 ALA A O 1 ATOM 4827 C CB . ALA A 1 604 ? -28.497 60.915 13.468 1.00 18.28 ? 657 ALA A CB 1 ATOM 4828 N N . TYR A 1 605 ? -27.949 64.094 13.286 1.00 22.24 ? 658 TYR A N 1 ATOM 4829 C CA . TYR A 1 605 ? -28.037 65.442 13.836 1.00 26.78 ? 658 TYR A CA 1 ATOM 4830 C C . TYR A 1 605 ? -28.870 66.349 12.950 1.00 27.39 ? 658 TYR A C 1 ATOM 4831 O O . TYR A 1 605 ? -29.750 67.064 13.435 1.00 23.61 ? 658 TYR A O 1 ATOM 4832 C CB . TYR A 1 605 ? -26.652 66.053 14.003 1.00 27.91 ? 658 TYR A CB 1 ATOM 4833 C CG . TYR A 1 605 ? -26.593 67.229 14.970 1.00 30.77 ? 658 TYR A CG 1 ATOM 4834 C CD1 . TYR A 1 605 ? -26.964 67.084 16.302 1.00 32.14 ? 658 TYR A CD1 1 ATOM 4835 C CD2 . TYR A 1 605 ? -26.149 68.476 14.548 1.00 31.59 ? 658 TYR A CD2 1 ATOM 4836 C CE1 . TYR A 1 605 ? -26.902 68.156 17.183 1.00 35.73 ? 658 TYR A CE1 1 ATOM 4837 C CE2 . TYR A 1 605 ? -26.080 69.548 15.420 1.00 32.23 ? 658 TYR A CE2 1 ATOM 4838 C CZ . TYR A 1 605 ? -26.445 69.383 16.733 1.00 35.30 ? 658 TYR A CZ 1 ATOM 4839 O OH . TYR A 1 605 ? -26.360 70.461 17.581 1.00 40.48 ? 658 TYR A OH 1 ATOM 4840 N N . ARG A 1 606 ? -28.567 66.337 11.655 1.00 29.47 ? 659 ARG A N 1 ATOM 4841 C CA . ARG A 1 606 ? -29.313 67.129 10.685 1.00 30.95 ? 659 ARG A CA 1 ATOM 4842 C C . ARG A 1 606 ? -30.773 66.703 10.649 1.00 30.01 ? 659 ARG A C 1 ATOM 4843 O O . ARG A 1 606 ? -31.656 67.511 10.391 1.00 30.13 ? 659 ARG A O 1 ATOM 4844 C CB . ARG A 1 606 ? -28.715 66.977 9.282 1.00 33.95 ? 659 ARG A CB 1 ATOM 4845 C CG . ARG A 1 606 ? -27.372 67.644 9.083 1.00 35.37 ? 659 ARG A CG 1 ATOM 4846 C CD . ARG A 1 606 ? -26.716 67.337 7.727 1.00 37.10 ? 659 ARG A CD 1 ATOM 4847 N NE . ARG A 1 606 ? -25.312 66.990 7.888 1.00 38.11 ? 659 ARG A NE 1 ATOM 4848 C CZ . ARG A 1 606 ? -24.783 65.846 7.497 1.00 37.18 ? 659 ARG A CZ 1 ATOM 4849 N NH1 . ARG A 1 606 ? -25.532 64.929 6.890 1.00 36.33 ? 659 ARG A NH1 1 ATOM 4850 N NH2 . ARG A 1 606 ? -23.498 65.623 7.705 1.00 36.00 ? 659 ARG A NH2 1 ATOM 4851 N N . ALA A 1 607 ? -31.037 65.428 10.899 1.00 30.74 ? 660 ALA A N 1 ATOM 4852 C CA . ALA A 1 607 ? -32.422 64.984 10.978 1.00 29.21 ? 660 ALA A CA 1 ATOM 4853 C C . ALA A 1 607 ? -33.090 65.452 12.278 1.00 28.44 ? 660 ALA A C 1 ATOM 4854 O O . ALA A 1 607 ? -34.294 65.709 12.285 1.00 31.15 ? 660 ALA A O 1 ATOM 4855 C CB . ALA A 1 607 ? -32.520 63.470 10.818 1.00 28.72 ? 660 ALA A CB 1 ATOM 4856 N N . TYR A 1 608 ? -32.321 65.589 13.360 1.00 24.81 ? 661 TYR A N 1 ATOM 4857 C CA . TYR A 1 608 ? -32.825 66.254 14.567 1.00 22.98 ? 661 TYR A CA 1 ATOM 4858 C C . TYR A 1 608 ? -32.988 67.761 14.351 1.00 24.67 ? 661 TYR A C 1 ATOM 4859 O O . TYR A 1 608 ? -33.983 68.362 14.767 1.00 22.58 ? 661 TYR A O 1 ATOM 4860 C CB . TYR A 1 608 ? -31.909 66.011 15.775 1.00 21.28 ? 661 TYR A CB 1 ATOM 4861 C CG . TYR A 1 608 ? -32.442 66.553 17.093 1.00 20.30 ? 661 TYR A CG 1 ATOM 4862 C CD1 . TYR A 1 608 ? -33.703 66.208 17.547 1.00 22.26 ? 661 TYR A CD1 1 ATOM 4863 C CD2 . TYR A 1 608 ? -31.678 67.399 17.888 1.00 22.85 ? 661 TYR A CD2 1 ATOM 4864 C CE1 . TYR A 1 608 ? -34.202 66.695 18.754 1.00 20.67 ? 661 TYR A CE1 1 ATOM 4865 C CE2 . TYR A 1 608 ? -32.163 67.889 19.093 1.00 21.15 ? 661 TYR A CE2 1 ATOM 4866 C CZ . TYR A 1 608 ? -33.434 67.533 19.519 1.00 22.79 ? 661 TYR A CZ 1 ATOM 4867 O OH . TYR A 1 608 ? -33.928 68.009 20.723 1.00 20.63 ? 661 TYR A OH 1 ATOM 4868 N N . GLN A 1 609 ? -32.004 68.381 13.720 1.00 25.84 ? 662 GLN A N 1 ATOM 4869 C CA . GLN A 1 609 ? -32.141 69.781 13.356 1.00 28.38 ? 662 GLN A CA 1 ATOM 4870 C C . GLN A 1 609 ? -33.425 69.963 12.553 1.00 29.22 ? 662 GLN A C 1 ATOM 4871 O O . GLN A 1 609 ? -34.248 70.813 12.868 1.00 29.33 ? 662 GLN A O 1 ATOM 4872 C CB . GLN A 1 609 ? -30.944 70.243 12.545 1.00 30.86 ? 662 GLN A CB 1 ATOM 4873 C CG . GLN A 1 609 ? -29.735 70.652 13.372 1.00 32.09 ? 662 GLN A CG 1 ATOM 4874 C CD . GLN A 1 609 ? -28.568 71.032 12.481 1.00 36.04 ? 662 GLN A CD 1 ATOM 4875 O OE1 . GLN A 1 609 ? -28.260 70.319 11.525 1.00 37.37 ? 662 GLN A OE1 1 ATOM 4876 N NE2 . GLN A 1 609 ? -27.929 72.163 12.775 1.00 38.84 ? 662 GLN A NE2 1 ATOM 4877 N N . ASN A 1 610 ? -33.610 69.145 11.529 1.00 28.30 ? 663 ASN A N 1 ATOM 4878 C CA . ASN A 1 610 ? -34.796 69.263 10.711 1.00 30.43 ? 663 ASN A CA 1 ATOM 4879 C C . ASN A 1 610 ? -36.073 69.044 11.528 1.00 33.51 ? 663 ASN A C 1 ATOM 4880 O O . ASN A 1 610 ? -37.114 69.611 11.217 1.00 36.73 ? 663 ASN A O 1 ATOM 4881 C CB . ASN A 1 610 ? -34.726 68.310 9.518 1.00 29.53 ? 663 ASN A CB 1 ATOM 4882 C CG . ASN A 1 610 ? -33.698 68.754 8.467 1.00 29.52 ? 663 ASN A CG 1 ATOM 4883 O OD1 . ASN A 1 610 ? -33.072 69.813 8.592 1.00 30.64 ? 663 ASN A OD1 1 ATOM 4884 N ND2 . ASN A 1 610 ? -33.525 67.944 7.432 1.00 26.41 ? 663 ASN A ND2 1 ATOM 4885 N N . TYR A 1 611 ? -35.986 68.243 12.587 1.00 36.72 ? 664 TYR A N 1 ATOM 4886 C CA . TYR A 1 611 ? -37.149 67.949 13.420 1.00 35.90 ? 664 TYR A CA 1 ATOM 4887 C C . TYR A 1 611 ? -37.511 69.147 14.275 1.00 36.49 ? 664 TYR A C 1 ATOM 4888 O O . TYR A 1 611 ? -38.688 69.481 14.431 1.00 35.87 ? 664 TYR A O 1 ATOM 4889 C CB . TYR A 1 611 ? -36.881 66.747 14.334 1.00 35.74 ? 664 TYR A CB 1 ATOM 4890 C CG . TYR A 1 611 ? -37.812 66.657 15.528 1.00 33.55 ? 664 TYR A CG 1 ATOM 4891 C CD1 . TYR A 1 611 ? -37.497 67.279 16.725 1.00 33.70 ? 664 TYR A CD1 1 ATOM 4892 C CD2 . TYR A 1 611 ? -39.003 65.955 15.453 1.00 34.63 ? 664 TYR A CD2 1 ATOM 4893 C CE1 . TYR A 1 611 ? -38.327 67.196 17.815 1.00 34.57 ? 664 TYR A CE1 1 ATOM 4894 C CE2 . TYR A 1 611 ? -39.853 65.869 16.538 1.00 34.70 ? 664 TYR A CE2 1 ATOM 4895 C CZ . TYR A 1 611 ? -39.514 66.493 17.719 1.00 35.41 ? 664 TYR A CZ 1 ATOM 4896 O OH . TYR A 1 611 ? -40.363 66.412 18.806 1.00 35.41 ? 664 TYR A OH 1 ATOM 4897 N N . ILE A 1 612 ? -36.495 69.778 14.847 1.00 36.60 ? 665 ILE A N 1 ATOM 4898 C CA . ILE A 1 612 ? -36.726 70.879 15.760 1.00 40.52 ? 665 ILE A CA 1 ATOM 4899 C C . ILE A 1 612 ? -37.264 72.090 15.010 1.00 41.92 ? 665 ILE A C 1 ATOM 4900 O O . ILE A 1 612 ? -38.197 72.745 15.468 1.00 42.44 ? 665 ILE A O 1 ATOM 4901 C CB . ILE A 1 612 ? -35.439 71.255 16.498 1.00 41.97 ? 665 ILE A CB 1 ATOM 4902 C CG1 . ILE A 1 612 ? -35.190 70.268 17.637 1.00 42.59 ? 665 ILE A CG1 1 ATOM 4903 C CG2 . ILE A 1 612 ? -35.549 72.672 17.036 1.00 43.37 ? 665 ILE A CG2 1 ATOM 4904 C CD1 . ILE A 1 612 ? -33.746 69.868 17.785 1.00 44.36 ? 665 ILE A CD1 1 ATOM 4905 N N . LYS A 1 613 ? -36.671 72.383 13.860 1.00 43.50 ? 666 LYS A N 1 ATOM 4906 C CA . LYS A 1 613 ? -37.179 73.433 12.991 1.00 46.31 ? 666 LYS A CA 1 ATOM 4907 C C . LYS A 1 613 ? -38.676 73.267 12.796 1.00 45.09 ? 666 LYS A C 1 ATOM 4908 O O . LYS A 1 613 ? -39.427 74.239 12.845 1.00 44.81 ? 666 LYS A O 1 ATOM 4909 C CB . LYS A 1 613 ? -36.472 73.402 11.635 1.00 48.72 ? 666 LYS A CB 1 ATOM 4910 C CG . LYS A 1 613 ? -36.562 74.714 10.860 1.00 50.82 ? 666 LYS A CG 1 ATOM 4911 C CD . LYS A 1 613 ? -36.053 74.557 9.422 1.00 52.23 ? 666 LYS A CD 1 ATOM 4912 C CE . LYS A 1 613 ? -35.223 73.283 9.252 1.00 52.25 ? 666 LYS A CE 1 ATOM 4913 N NZ . LYS A 1 613 ? -34.360 73.323 8.036 1.00 52.51 ? 666 LYS A NZ 1 ATOM 4914 N N . LYS A 1 614 ? -39.108 72.035 12.568 1.00 43.97 ? 667 LYS A N 1 ATOM 4915 C CA . LYS A 1 614 ? -40.491 71.785 12.181 1.00 45.73 ? 667 LYS A CA 1 ATOM 4916 C C . LYS A 1 614 ? -41.434 71.744 13.385 1.00 45.05 ? 667 LYS A C 1 ATOM 4917 O O . LYS A 1 614 ? -42.603 72.116 13.267 1.00 45.20 ? 667 LYS A O 1 ATOM 4918 C CB . LYS A 1 614 ? -40.596 70.482 11.398 1.00 47.46 ? 667 LYS A CB 1 ATOM 4919 C CG . LYS A 1 614 ? -41.892 69.736 11.624 1.00 49.71 ? 667 LYS A CG 1 ATOM 4920 C CD . LYS A 1 614 ? -42.523 69.311 10.307 1.00 51.55 ? 667 LYS A CD 1 ATOM 4921 C CE . LYS A 1 614 ? -41.469 69.080 9.227 1.00 52.48 ? 667 LYS A CE 1 ATOM 4922 N NZ . LYS A 1 614 ? -41.702 67.811 8.475 1.00 52.04 ? 667 LYS A NZ 1 ATOM 4923 N N . ASN A 1 615 ? -40.934 71.298 14.539 1.00 42.76 ? 668 ASN A N 1 ATOM 4924 C CA . ASN A 1 615 ? -41.805 71.056 15.692 1.00 42.04 ? 668 ASN A CA 1 ATOM 4925 C C . ASN A 1 615 ? -41.445 71.901 16.915 1.00 42.24 ? 668 ASN A C 1 ATOM 4926 O O . ASN A 1 615 ? -42.185 71.914 17.903 1.00 43.31 ? 668 ASN A O 1 ATOM 4927 C CB . ASN A 1 615 ? -41.798 69.577 16.086 1.00 41.37 ? 668 ASN A CB 1 ATOM 4928 C CG . ASN A 1 615 ? -42.139 68.663 14.933 1.00 40.09 ? 668 ASN A CG 1 ATOM 4929 O OD1 . ASN A 1 615 ? -43.306 68.418 14.654 1.00 42.36 ? 668 ASN A OD1 1 ATOM 4930 N ND2 . ASN A 1 615 ? -41.119 68.147 14.259 1.00 39.09 ? 668 ASN A ND2 1 ATOM 4931 N N . GLY A 1 616 ? -40.326 72.611 16.845 1.00 41.17 ? 669 GLY A N 1 ATOM 4932 C CA . GLY A 1 616 ? -39.912 73.482 17.931 1.00 42.00 ? 669 GLY A CA 1 ATOM 4933 C C . GLY A 1 616 ? -39.171 72.713 19.007 1.00 41.15 ? 669 GLY A C 1 ATOM 4934 O O . GLY A 1 616 ? -39.084 71.495 18.950 1.00 37.24 ? 669 GLY A O 1 ATOM 4935 N N . GLU A 1 617 ? -38.619 73.422 19.983 1.00 43.21 ? 670 GLU A N 1 ATOM 4936 C CA . GLU A 1 617 ? -37.610 72.829 20.845 1.00 44.90 ? 670 GLU A CA 1 ATOM 4937 C C . GLU A 1 617 ? -38.280 71.870 21.822 1.00 43.33 ? 670 GLU A C 1 ATOM 4938 O O . GLU A 1 617 ? -39.495 71.914 22.010 1.00 41.92 ? 670 GLU A O 1 ATOM 4939 C CB . GLU A 1 617 ? -36.818 73.911 21.581 1.00 48.07 ? 670 GLU A CB 1 ATOM 4940 C CG . GLU A 1 617 ? -35.494 74.265 20.913 1.00 51.19 ? 670 GLU A CG 1 ATOM 4941 C CD . GLU A 1 617 ? -35.045 75.690 21.211 1.00 54.59 ? 670 GLU A CD 1 ATOM 4942 O OE1 . GLU A 1 617 ? -33.910 75.876 21.706 1.00 57.74 ? 670 GLU A OE1 1 ATOM 4943 O OE2 . GLU A 1 617 ? -35.820 76.632 20.948 1.00 55.14 ? 670 GLU A OE2 1 ATOM 4944 N N . GLU A 1 618 ? -37.495 70.984 22.427 1.00 42.83 ? 671 GLU A N 1 ATOM 4945 C CA . GLU A 1 618 ? -38.034 70.079 23.434 1.00 42.18 ? 671 GLU A CA 1 ATOM 4946 C C . GLU A 1 618 ? -37.827 70.641 24.823 1.00 40.54 ? 671 GLU A C 1 ATOM 4947 O O . GLU A 1 618 ? -36.880 71.387 25.084 1.00 37.79 ? 671 GLU A O 1 ATOM 4948 C CB . GLU A 1 618 ? -37.385 68.702 23.348 1.00 42.65 ? 671 GLU A CB 1 ATOM 4949 C CG . GLU A 1 618 ? -37.026 68.281 21.939 1.00 44.54 ? 671 GLU A CG 1 ATOM 4950 C CD . GLU A 1 618 ? -36.456 66.880 21.886 1.00 44.20 ? 671 GLU A CD 1 ATOM 4951 O OE1 . GLU A 1 618 ? -35.384 66.699 21.272 1.00 45.20 ? 671 GLU A OE1 1 ATOM 4952 O OE2 . GLU A 1 618 ? -37.088 65.967 22.450 1.00 44.38 ? 671 GLU A OE2 1 ATOM 4953 N N . LYS A 1 619 ? -38.719 70.259 25.723 1.00 40.14 ? 672 LYS A N 1 ATOM 4954 C CA . LYS A 1 619 ? -38.538 70.577 27.120 1.00 38.62 ? 672 LYS A CA 1 ATOM 4955 C C . LYS A 1 619 ? -37.314 69.849 27.646 1.00 37.55 ? 672 LYS A C 1 ATOM 4956 O O . LYS A 1 619 ? -37.008 68.724 27.224 1.00 31.26 ? 672 LYS A O 1 ATOM 4957 C CB . LYS A 1 619 ? -39.788 70.212 27.905 1.00 41.24 ? 672 LYS A CB 1 ATOM 4958 C CG . LYS A 1 619 ? -41.000 71.053 27.498 1.00 43.20 ? 672 LYS A CG 1 ATOM 4959 C CD . LYS A 1 619 ? -41.753 71.587 28.708 1.00 45.31 ? 672 LYS A CD 1 ATOM 4960 C CE . LYS A 1 619 ? -43.109 70.903 28.816 1.00 47.09 ? 672 LYS A CE 1 ATOM 4961 N NZ . LYS A 1 619 ? -43.305 69.950 27.674 1.00 46.35 ? 672 LYS A NZ 1 ATOM 4962 N N . LEU A 1 620 ? -36.599 70.521 28.541 1.00 33.45 ? 673 LEU A N 1 ATOM 4963 C CA . LEU A 1 620 ? -35.281 70.082 28.947 1.00 33.93 ? 673 LEU A CA 1 ATOM 4964 C C . LEU A 1 620 ? -35.462 68.943 29.938 1.00 32.24 ? 673 LEU A C 1 ATOM 4965 O O . LEU A 1 620 ? -36.565 68.724 30.440 1.00 30.20 ? 673 LEU A O 1 ATOM 4966 C CB . LEU A 1 620 ? -34.510 71.242 29.583 1.00 34.62 ? 673 LEU A CB 1 ATOM 4967 C CG . LEU A 1 620 ? -34.606 72.585 28.846 1.00 36.87 ? 673 LEU A CG 1 ATOM 4968 C CD1 . LEU A 1 620 ? -34.406 73.765 29.793 1.00 37.09 ? 673 LEU A CD1 1 ATOM 4969 C CD2 . LEU A 1 620 ? -33.603 72.652 27.696 1.00 36.74 ? 673 LEU A CD2 1 ATOM 4970 N N . LEU A 1 621 ? -34.383 68.223 30.216 1.00 31.15 ? 674 LEU A N 1 ATOM 4971 C CA . LEU A 1 621 ? -34.422 67.122 31.173 1.00 30.18 ? 674 LEU A CA 1 ATOM 4972 C C . LEU A 1 621 ? -34.037 67.624 32.553 1.00 26.54 ? 674 LEU A C 1 ATOM 4973 O O . LEU A 1 621 ? -33.145 68.437 32.686 1.00 25.50 ? 674 LEU A O 1 ATOM 4974 C CB . LEU A 1 621 ? -33.462 66.009 30.742 1.00 30.11 ? 674 LEU A CB 1 ATOM 4975 C CG . LEU A 1 621 ? -33.980 65.033 29.680 1.00 30.52 ? 674 LEU A CG 1 ATOM 4976 C CD1 . LEU A 1 621 ? -33.034 63.851 29.517 1.00 28.86 ? 674 LEU A CD1 1 ATOM 4977 C CD2 . LEU A 1 621 ? -35.364 64.548 30.024 1.00 31.58 ? 674 LEU A CD2 1 ATOM 4978 N N . PRO A 1 622 ? -34.705 67.133 33.584 1.00 26.85 ? 675 PRO A N 1 ATOM 4979 C CA . PRO A 1 622 ? -34.444 67.591 34.949 1.00 27.76 ? 675 PRO A CA 1 ATOM 4980 C C . PRO A 1 622 ? -33.147 67.015 35.482 1.00 29.94 ? 675 PRO A C 1 ATOM 4981 O O . PRO A 1 622 ? -32.823 65.860 35.204 1.00 31.82 ? 675 PRO A O 1 ATOM 4982 C CB . PRO A 1 622 ? -35.636 67.048 35.731 1.00 26.55 ? 675 PRO A CB 1 ATOM 4983 C CG . PRO A 1 622 ? -36.066 65.855 34.979 1.00 27.29 ? 675 PRO A CG 1 ATOM 4984 C CD . PRO A 1 622 ? -35.743 66.094 33.536 1.00 26.89 ? 675 PRO A CD 1 ATOM 4985 N N . GLY A 1 623 ? -32.403 67.826 36.222 1.00 29.57 ? 676 GLY A N 1 ATOM 4986 C CA . GLY A 1 623 ? -31.206 67.366 36.896 1.00 30.11 ? 676 GLY A CA 1 ATOM 4987 C C . GLY A 1 623 ? -29.975 67.505 36.029 1.00 28.64 ? 676 GLY A C 1 ATOM 4988 O O . GLY A 1 623 ? -28.879 67.155 36.441 1.00 31.98 ? 676 GLY A O 1 ATOM 4989 N N . LEU A 1 624 ? -30.156 68.011 34.820 1.00 29.24 ? 677 LEU A N 1 ATOM 4990 C CA . LEU A 1 624 ? -29.057 68.112 33.875 1.00 30.93 ? 677 LEU A CA 1 ATOM 4991 C C . LEU A 1 624 ? -28.956 69.528 33.327 1.00 32.63 ? 677 LEU A C 1 ATOM 4992 O O . LEU A 1 624 ? -29.908 70.044 32.744 1.00 33.22 ? 677 LEU A O 1 ATOM 4993 C CB . LEU A 1 624 ? -29.259 67.127 32.724 1.00 31.79 ? 677 LEU A CB 1 ATOM 4994 C CG . LEU A 1 624 ? -28.825 65.691 33.016 1.00 30.19 ? 677 LEU A CG 1 ATOM 4995 C CD1 . LEU A 1 624 ? -29.673 64.695 32.236 1.00 29.35 ? 677 LEU A CD1 1 ATOM 4996 C CD2 . LEU A 1 624 ? -27.356 65.520 32.691 1.00 30.07 ? 677 LEU A CD2 1 ATOM 4997 N N . ASP A 1 625 ? -27.800 70.153 33.528 1.00 34.10 ? 678 ASP A N 1 ATOM 4998 C CA . ASP A 1 625 ? -27.528 71.474 32.970 1.00 35.22 ? 678 ASP A CA 1 ATOM 4999 C C . ASP A 1 625 ? -27.041 71.368 31.524 1.00 33.07 ? 678 ASP A C 1 ATOM 5000 O O . ASP A 1 625 ? -25.949 71.833 31.181 1.00 30.99 ? 678 ASP A O 1 ATOM 5001 C CB . ASP A 1 625 ? -26.483 72.204 33.821 1.00 38.09 ? 678 ASP A CB 1 ATOM 5002 C CG . ASP A 1 625 ? -26.925 72.390 35.266 1.00 40.91 ? 678 ASP A CG 1 ATOM 5003 O OD1 . ASP A 1 625 ? -28.133 72.269 35.542 1.00 42.82 ? 678 ASP A OD1 1 ATOM 5004 O OD2 . ASP A 1 625 ? -26.137 72.673 36.194 1.00 45.85 ? 678 ASP A OD2 1 ATOM 5005 N N . LEU A 1 626 ? -27.861 70.749 30.683 1.00 30.29 ? 679 LEU A N 1 ATOM 5006 C CA . LEU A 1 626 ? -27.529 70.582 29.273 1.00 30.88 ? 679 LEU A CA 1 ATOM 5007 C C . LEU A 1 626 ? -28.758 70.871 28.436 1.00 25.86 ? 679 LEU A C 1 ATOM 5008 O O . LEU A 1 626 ? -29.856 70.520 28.822 1.00 24.56 ? 679 LEU A O 1 ATOM 5009 C CB . LEU A 1 626 ? -27.067 69.154 29.005 1.00 30.73 ? 679 LEU A CB 1 ATOM 5010 C CG . LEU A 1 626 ? -25.722 68.766 29.608 1.00 32.22 ? 679 LEU A CG 1 ATOM 5011 C CD1 . LEU A 1 626 ? -25.358 67.341 29.210 1.00 31.80 ? 679 LEU A CD1 1 ATOM 5012 C CD2 . LEU A 1 626 ? -24.653 69.746 29.166 1.00 31.09 ? 679 LEU A CD2 1 ATOM 5013 N N . ASN A 1 627 ? -28.571 71.495 27.284 1.00 23.74 ? 680 ASN A N 1 ATOM 5014 C CA . ASN A 1 627 ? -29.626 71.536 26.283 1.00 26.47 ? 680 ASN A CA 1 ATOM 5015 C C . ASN A 1 627 ? -29.588 70.311 25.383 1.00 27.55 ? 680 ASN A C 1 ATOM 5016 O O . ASN A 1 627 ? -28.750 69.420 25.564 1.00 27.32 ? 680 ASN A O 1 ATOM 5017 C CB . ASN A 1 627 ? -29.509 72.802 25.436 1.00 26.91 ? 680 ASN A CB 1 ATOM 5018 C CG . ASN A 1 627 ? -28.234 72.842 24.633 1.00 27.52 ? 680 ASN A CG 1 ATOM 5019 O OD1 . ASN A 1 627 ? -27.631 71.807 24.377 1.00 28.02 ? 680 ASN A OD1 1 ATOM 5020 N ND2 . ASN A 1 627 ? -27.806 74.044 24.237 1.00 28.40 ? 680 ASN A ND2 1 ATOM 5021 N N . HIS A 1 628 ? -30.486 70.271 24.404 1.00 29.18 ? 681 HIS A N 1 ATOM 5022 C CA . HIS A 1 628 ? -30.790 69.027 23.710 1.00 33.36 ? 681 HIS A CA 1 ATOM 5023 C C . HIS A 1 628 ? -29.770 68.701 22.641 1.00 32.11 ? 681 HIS A C 1 ATOM 5024 O O . HIS A 1 628 ? -29.554 67.533 22.339 1.00 31.39 ? 681 HIS A O 1 ATOM 5025 C CB . HIS A 1 628 ? -32.168 69.074 23.067 1.00 35.96 ? 681 HIS A CB 1 ATOM 5026 C CG . HIS A 1 628 ? -33.273 68.689 23.994 1.00 38.24 ? 681 HIS A CG 1 ATOM 5027 N ND1 . HIS A 1 628 ? -33.076 68.502 25.341 1.00 42.65 ? 681 HIS A ND1 1 ATOM 5028 C CD2 . HIS A 1 628 ? -34.587 68.463 23.772 1.00 42.22 ? 681 HIS A CD2 1 ATOM 5029 C CE1 . HIS A 1 628 ? -34.222 68.179 25.913 1.00 42.90 ? 681 HIS A CE1 1 ATOM 5030 N NE2 . HIS A 1 628 ? -35.156 68.149 24.982 1.00 43.69 ? 681 HIS A NE2 1 ATOM 5031 N N . LYS A 1 629 ? -29.159 69.728 22.055 1.00 31.83 ? 682 LYS A N 1 ATOM 5032 C CA . LYS A 1 629 ? -28.017 69.513 21.181 1.00 32.16 ? 682 LYS A CA 1 ATOM 5033 C C . LYS A 1 629 ? -26.950 68.798 21.980 1.00 28.60 ? 682 LYS A C 1 ATOM 5034 O O . LYS A 1 629 ? -26.354 67.835 21.508 1.00 26.47 ? 682 LYS A O 1 ATOM 5035 C CB . LYS A 1 629 ? -27.484 70.835 20.627 1.00 35.44 ? 682 LYS A CB 1 ATOM 5036 C CG . LYS A 1 629 ? -28.581 71.860 20.334 1.00 40.65 ? 682 LYS A CG 1 ATOM 5037 C CD . LYS A 1 629 ? -28.165 72.858 19.249 1.00 43.11 ? 682 LYS A CD 1 ATOM 5038 C CE . LYS A 1 629 ? -29.073 72.772 18.024 1.00 45.98 ? 682 LYS A CE 1 ATOM 5039 N NZ . LYS A 1 629 ? -28.277 72.573 16.778 1.00 48.56 ? 682 LYS A NZ 1 ATOM 5040 N N . GLN A 1 630 ? -26.743 69.251 23.213 1.00 26.47 ? 683 GLN A N 1 ATOM 5041 C CA . GLN A 1 630 ? -25.786 68.611 24.095 1.00 27.99 ? 683 GLN A CA 1 ATOM 5042 C C . GLN A 1 630 ? -26.240 67.180 24.418 1.00 26.60 ? 683 GLN A C 1 ATOM 5043 O O . GLN A 1 630 ? -25.436 66.256 24.369 1.00 29.96 ? 683 GLN A O 1 ATOM 5044 C CB . GLN A 1 630 ? -25.577 69.434 25.377 1.00 28.33 ? 683 GLN A CB 1 ATOM 5045 C CG . GLN A 1 630 ? -25.067 70.862 25.145 1.00 29.07 ? 683 GLN A CG 1 ATOM 5046 C CD . GLN A 1 630 ? -25.023 71.709 26.427 1.00 30.15 ? 683 GLN A CD 1 ATOM 5047 O OE1 . GLN A 1 630 ? -25.905 71.614 27.297 1.00 29.10 ? 683 GLN A OE1 1 ATOM 5048 N NE2 . GLN A 1 630 ? -23.995 72.535 26.540 1.00 31.62 ? 683 GLN A NE2 1 ATOM 5049 N N . LEU A 1 631 ? -27.523 67.004 24.739 1.00 26.74 ? 684 LEU A N 1 ATOM 5050 C CA . LEU A 1 631 ? -28.061 65.684 25.076 1.00 24.70 ? 684 LEU A CA 1 ATOM 5051 C C . LEU A 1 631 ? -27.928 64.732 23.907 1.00 22.94 ? 684 LEU A C 1 ATOM 5052 O O . LEU A 1 631 ? -27.625 63.563 24.089 1.00 20.27 ? 684 LEU A O 1 ATOM 5053 C CB . LEU A 1 631 ? -29.531 65.756 25.471 1.00 23.48 ? 684 LEU A CB 1 ATOM 5054 C CG . LEU A 1 631 ? -29.854 66.444 26.789 1.00 25.64 ? 684 LEU A CG 1 ATOM 5055 C CD1 . LEU A 1 631 ? -31.349 66.675 26.882 1.00 24.24 ? 684 LEU A CD1 1 ATOM 5056 C CD2 . LEU A 1 631 ? -29.333 65.643 27.977 1.00 25.46 ? 684 LEU A CD2 1 ATOM 5057 N N . PHE A 1 632 ? -28.151 65.246 22.704 1.00 22.05 ? 685 PHE A N 1 ATOM 5058 C CA . PHE A 1 632 ? -28.022 64.443 21.506 1.00 19.23 ? 685 PHE A CA 1 ATOM 5059 C C . PHE A 1 632 ? -26.705 63.689 21.516 1.00 20.96 ? 685 PHE A C 1 ATOM 5060 O O . PHE A 1 632 ? -26.675 62.491 21.238 1.00 20.63 ? 685 PHE A O 1 ATOM 5061 C CB . PHE A 1 632 ? -28.083 65.320 20.259 1.00 20.38 ? 685 PHE A CB 1 ATOM 5062 C CG . PHE A 1 632 ? -27.759 64.582 18.993 1.00 15.99 ? 685 PHE A CG 1 ATOM 5063 C CD1 . PHE A 1 632 ? -26.466 64.510 18.536 1.00 19.21 ? 685 PHE A CD1 1 ATOM 5064 C CD2 . PHE A 1 632 ? -28.745 63.939 18.289 1.00 18.22 ? 685 PHE A CD2 1 ATOM 5065 C CE1 . PHE A 1 632 ? -26.161 63.811 17.381 1.00 19.46 ? 685 PHE A CE1 1 ATOM 5066 C CE2 . PHE A 1 632 ? -28.458 63.246 17.131 1.00 19.80 ? 685 PHE A CE2 1 ATOM 5067 C CZ . PHE A 1 632 ? -27.155 63.180 16.677 1.00 19.06 ? 685 PHE A CZ 1 ATOM 5068 N N . PHE A 1 633 ? -25.620 64.405 21.816 1.00 23.35 ? 686 PHE A N 1 ATOM 5069 C CA . PHE A 1 633 ? -24.256 63.860 21.773 1.00 23.29 ? 686 PHE A CA 1 ATOM 5070 C C . PHE A 1 633 ? -23.895 63.035 23.018 1.00 23.25 ? 686 PHE A C 1 ATOM 5071 O O . PHE A 1 633 ? -23.107 62.085 22.945 1.00 22.88 ? 686 PHE A O 1 ATOM 5072 C CB . PHE A 1 633 ? -23.242 65.000 21.645 1.00 23.78 ? 686 PHE A CB 1 ATOM 5073 C CG . PHE A 1 633 ? -23.227 65.637 20.298 1.00 25.07 ? 686 PHE A CG 1 ATOM 5074 C CD1 . PHE A 1 633 ? -23.617 66.950 20.139 1.00 23.93 ? 686 PHE A CD1 1 ATOM 5075 C CD2 . PHE A 1 633 ? -22.831 64.918 19.179 1.00 24.52 ? 686 PHE A CD2 1 ATOM 5076 C CE1 . PHE A 1 633 ? -23.605 67.544 18.884 1.00 22.46 ? 686 PHE A CE1 1 ATOM 5077 C CE2 . PHE A 1 633 ? -22.836 65.503 17.928 1.00 23.57 ? 686 PHE A CE2 1 ATOM 5078 C CZ . PHE A 1 633 ? -23.215 66.818 17.783 1.00 20.09 ? 686 PHE A CZ 1 ATOM 5079 N N . LEU A 1 634 ? -24.440 63.433 24.162 1.00 19.94 ? 687 LEU A N 1 ATOM 5080 C CA . LEU A 1 634 ? -24.352 62.635 25.370 1.00 20.19 ? 687 LEU A CA 1 ATOM 5081 C C . LEU A 1 634 ? -24.752 61.209 25.082 1.00 20.36 ? 687 LEU A C 1 ATOM 5082 O O . LEU A 1 634 ? -24.048 60.260 25.431 1.00 21.21 ? 687 LEU A O 1 ATOM 5083 C CB . LEU A 1 634 ? -25.279 63.195 26.445 1.00 22.33 ? 687 LEU A CB 1 ATOM 5084 C CG . LEU A 1 634 ? -24.602 63.396 27.790 1.00 20.69 ? 687 LEU A CG 1 ATOM 5085 C CD1 . LEU A 1 634 ? -25.632 63.441 28.903 1.00 23.72 ? 687 LEU A CD1 1 ATOM 5086 C CD2 . LEU A 1 634 ? -23.579 62.321 28.024 1.00 18.53 ? 687 LEU A CD2 1 ATOM 5087 N N . ASN A 1 635 ? -25.897 61.067 24.442 1.00 16.81 ? 688 ASN A N 1 ATOM 5088 C CA . ASN A 1 635 ? -26.535 59.777 24.343 1.00 19.97 ? 688 ASN A CA 1 ATOM 5089 C C . ASN A 1 635 ? -25.828 58.924 23.298 1.00 20.06 ? 688 ASN A C 1 ATOM 5090 O O . ASN A 1 635 ? -25.590 57.734 23.516 1.00 18.34 ? 688 ASN A O 1 ATOM 5091 C CB . ASN A 1 635 ? -28.014 59.949 23.997 1.00 19.68 ? 688 ASN A CB 1 ATOM 5092 C CG . ASN A 1 635 ? -28.843 58.733 24.370 1.00 19.02 ? 688 ASN A CG 1 ATOM 5093 O OD1 . ASN A 1 635 ? -29.608 58.211 23.563 1.00 20.28 ? 688 ASN A OD1 1 ATOM 5094 N ND2 . ASN A 1 635 ? -28.685 58.276 25.587 1.00 17.38 ? 688 ASN A ND2 1 ATOM 5095 N N . PHE A 1 636 ? -25.481 59.553 22.177 1.00 21.40 ? 689 PHE A N 1 ATOM 5096 C CA . PHE A 1 636 ? -24.554 58.971 21.220 1.00 20.58 ? 689 PHE A CA 1 ATOM 5097 C C . PHE A 1 636 ? -23.391 58.322 21.944 1.00 20.01 ? 689 PHE A C 1 ATOM 5098 O O . PHE A 1 636 ? -23.122 57.142 21.743 1.00 18.33 ? 689 PHE A O 1 ATOM 5099 C CB . PHE A 1 636 ? -24.046 60.027 20.253 1.00 21.98 ? 689 PHE A CB 1 ATOM 5100 C CG . PHE A 1 636 ? -22.877 59.582 19.439 1.00 20.99 ? 689 PHE A CG 1 ATOM 5101 C CD1 . PHE A 1 636 ? -21.618 60.116 19.662 1.00 19.36 ? 689 PHE A CD1 1 ATOM 5102 C CD2 . PHE A 1 636 ? -23.029 58.616 18.462 1.00 19.65 ? 689 PHE A CD2 1 ATOM 5103 C CE1 . PHE A 1 636 ? -20.519 59.691 18.925 1.00 19.40 ? 689 PHE A CE1 1 ATOM 5104 C CE2 . PHE A 1 636 ? -21.943 58.200 17.711 1.00 21.74 ? 689 PHE A CE2 1 ATOM 5105 C CZ . PHE A 1 636 ? -20.674 58.743 17.947 1.00 21.86 ? 689 PHE A CZ 1 ATOM 5106 N N . ALA A 1 637 ? -22.732 59.072 22.824 1.00 21.87 ? 690 ALA A N 1 ATOM 5107 C CA . ALA A 1 637 ? -21.532 58.570 23.498 1.00 22.01 ? 690 ALA A CA 1 ATOM 5108 C C . ALA A 1 637 ? -21.850 57.477 24.517 1.00 19.80 ? 690 ALA A C 1 ATOM 5109 O O . ALA A 1 637 ? -21.061 56.549 24.714 1.00 16.78 ? 690 ALA A O 1 ATOM 5110 C CB . ALA A 1 637 ? -20.770 59.714 24.175 1.00 22.22 ? 690 ALA A CB 1 ATOM 5111 N N . GLN A 1 638 ? -22.986 57.588 25.190 1.00 20.18 ? 691 GLN A N 1 ATOM 5112 C CA . GLN A 1 638 ? -23.244 56.693 26.313 1.00 21.88 ? 691 GLN A CA 1 ATOM 5113 C C . GLN A 1 638 ? -23.622 55.301 25.815 1.00 20.82 ? 691 GLN A C 1 ATOM 5114 O O . GLN A 1 638 ? -23.464 54.323 26.530 1.00 23.26 ? 691 GLN A O 1 ATOM 5115 C CB . GLN A 1 638 ? -24.291 57.276 27.276 1.00 22.58 ? 691 GLN A CB 1 ATOM 5116 C CG . GLN A 1 638 ? -23.670 58.260 28.293 1.00 21.54 ? 691 GLN A CG 1 ATOM 5117 C CD . GLN A 1 638 ? -24.612 58.673 29.424 1.00 24.44 ? 691 GLN A CD 1 ATOM 5118 O OE1 . GLN A 1 638 ? -25.662 58.064 29.634 1.00 25.37 ? 691 GLN A OE1 1 ATOM 5119 N NE2 . GLN A 1 638 ? -24.219 59.704 30.169 1.00 27.47 ? 691 GLN A NE2 1 ATOM 5120 N N . VAL A 1 639 ? -24.049 55.201 24.563 1.00 21.45 ? 692 VAL A N 1 ATOM 5121 C CA . VAL A 1 639 ? -24.202 53.898 23.938 1.00 21.67 ? 692 VAL A CA 1 ATOM 5122 C C . VAL A 1 639 ? -22.942 53.062 24.130 1.00 24.74 ? 692 VAL A C 1 ATOM 5123 O O . VAL A 1 639 ? -22.998 51.832 24.139 1.00 26.96 ? 692 VAL A O 1 ATOM 5124 C CB . VAL A 1 639 ? -24.514 54.020 22.447 1.00 23.40 ? 692 VAL A CB 1 ATOM 5125 C CG1 . VAL A 1 639 ? -24.125 52.757 21.713 1.00 24.28 ? 692 VAL A CG1 1 ATOM 5126 C CG2 . VAL A 1 639 ? -25.986 54.329 22.238 1.00 23.22 ? 692 VAL A CG2 1 ATOM 5127 N N . TRP A 1 640 ? -21.801 53.716 24.297 1.00 23.59 ? 693 TRP A N 1 ATOM 5128 C CA . TRP A 1 640 ? -20.542 52.997 24.256 1.00 22.52 ? 693 TRP A CA 1 ATOM 5129 C C . TRP A 1 640 ? -19.754 53.095 25.548 1.00 21.17 ? 693 TRP A C 1 ATOM 5130 O O . TRP A 1 640 ? -18.606 52.651 25.591 1.00 26.19 ? 693 TRP A O 1 ATOM 5131 C CB . TRP A 1 640 ? -19.686 53.476 23.072 1.00 24.08 ? 693 TRP A CB 1 ATOM 5132 C CG . TRP A 1 640 ? -20.250 53.041 21.794 1.00 23.76 ? 693 TRP A CG 1 ATOM 5133 C CD1 . TRP A 1 640 ? -20.677 53.828 20.774 1.00 25.89 ? 693 TRP A CD1 1 ATOM 5134 C CD2 . TRP A 1 640 ? -20.508 51.692 21.398 1.00 24.92 ? 693 TRP A CD2 1 ATOM 5135 N NE1 . TRP A 1 640 ? -21.168 53.051 19.754 1.00 26.42 ? 693 TRP A NE1 1 ATOM 5136 C CE2 . TRP A 1 640 ? -21.074 51.734 20.114 1.00 24.46 ? 693 TRP A CE2 1 ATOM 5137 C CE3 . TRP A 1 640 ? -20.312 50.443 22.001 1.00 24.14 ? 693 TRP A CE3 1 ATOM 5138 C CZ2 . TRP A 1 640 ? -21.450 50.588 19.427 1.00 23.64 ? 693 TRP A CZ2 1 ATOM 5139 C CZ3 . TRP A 1 640 ? -20.682 49.303 21.311 1.00 23.96 ? 693 TRP A CZ3 1 ATOM 5140 C CH2 . TRP A 1 640 ? -21.251 49.385 20.045 1.00 23.85 ? 693 TRP A CH2 1 ATOM 5141 N N . CYS A 1 641 ? -20.351 53.620 26.615 1.00 19.65 ? 694 CYS A N 1 ATOM 5142 C CA . CYS A 1 641 ? -19.742 53.442 27.941 1.00 20.23 ? 694 CYS A CA 1 ATOM 5143 C C . CYS A 1 641 ? -19.473 51.951 28.146 1.00 19.40 ? 694 CYS A C 1 ATOM 5144 O O . CYS A 1 641 ? -20.368 51.130 27.988 1.00 18.99 ? 694 CYS A O 1 ATOM 5145 C CB . CYS A 1 641 ? -20.637 53.949 29.076 1.00 19.72 ? 694 CYS A CB 1 ATOM 5146 S SG . CYS A 1 641 ? -21.083 55.702 29.016 1.00 20.89 ? 694 CYS A SG 1 ATOM 5147 N N . GLY A 1 642 ? -18.238 51.612 28.493 1.00 19.03 ? 695 GLY A N 1 ATOM 5148 C CA . GLY A 1 642 ? -17.775 50.238 28.421 1.00 18.15 ? 695 GLY A CA 1 ATOM 5149 C C . GLY A 1 642 ? -16.280 50.125 28.615 1.00 15.95 ? 695 GLY A C 1 ATOM 5150 O O . GLY A 1 642 ? -15.554 51.099 28.570 1.00 17.21 ? 695 GLY A O 1 ATOM 5151 N N . THR A 1 643 ? -15.805 48.918 28.839 1.00 19.98 ? 696 THR A N 1 ATOM 5152 C CA . THR A 1 643 ? -14.369 48.689 28.923 1.00 20.22 ? 696 THR A CA 1 ATOM 5153 C C . THR A 1 643 ? -14.109 47.269 28.464 1.00 17.62 ? 696 THR A C 1 ATOM 5154 O O . THR A 1 643 ? -15.058 46.523 28.216 1.00 20.75 ? 696 THR A O 1 ATOM 5155 C CB . THR A 1 643 ? -13.860 48.938 30.371 1.00 24.02 ? 696 THR A CB 1 ATOM 5156 O OG1 . THR A 1 643 ? -12.484 48.540 30.495 1.00 24.91 ? 696 THR A OG1 1 ATOM 5157 C CG2 . THR A 1 643 ? -14.597 48.057 31.382 1.00 25.08 ? 696 THR A CG2 1 ATOM 5158 N N . TYR A 1 644 ? -12.840 46.905 28.323 1.00 17.44 ? 697 TYR A N 1 ATOM 5159 C CA . TYR A 1 644 ? -12.445 45.593 27.827 1.00 15.76 ? 697 TYR A CA 1 ATOM 5160 C C . TYR A 1 644 ? -11.425 44.977 28.784 1.00 17.13 ? 697 TYR A C 1 ATOM 5161 O O . TYR A 1 644 ? -10.671 45.692 29.427 1.00 17.25 ? 697 TYR A O 1 ATOM 5162 C CB . TYR A 1 644 ? -11.793 45.693 26.449 1.00 17.62 ? 697 TYR A CB 1 ATOM 5163 C CG . TYR A 1 644 ? -12.662 46.210 25.309 1.00 20.02 ? 697 TYR A CG 1 ATOM 5164 C CD1 . TYR A 1 644 ? -12.941 45.406 24.190 1.00 21.77 ? 697 TYR A CD1 1 ATOM 5165 C CD2 . TYR A 1 644 ? -13.154 47.506 25.320 1.00 17.06 ? 697 TYR A CD2 1 ATOM 5166 C CE1 . TYR A 1 644 ? -13.724 45.888 23.125 1.00 18.45 ? 697 TYR A CE1 1 ATOM 5167 C CE2 . TYR A 1 644 ? -13.928 47.981 24.280 1.00 20.44 ? 697 TYR A CE2 1 ATOM 5168 C CZ . TYR A 1 644 ? -14.214 47.171 23.192 1.00 19.81 ? 697 TYR A CZ 1 ATOM 5169 O OH . TYR A 1 644 ? -14.983 47.677 22.174 1.00 25.63 ? 697 TYR A OH 1 ATOM 5170 N N . ARG A 1 645 ? -11.373 43.650 28.840 1.00 16.74 ? 698 ARG A N 1 ATOM 5171 C CA . ARG A 1 645 ? -10.219 42.955 29.385 1.00 15.80 ? 698 ARG A CA 1 ATOM 5172 C C . ARG A 1 645 ? -9.024 43.015 28.425 1.00 18.81 ? 698 ARG A C 1 ATOM 5173 O O . ARG A 1 645 ? -9.173 42.837 27.217 1.00 17.72 ? 698 ARG A O 1 ATOM 5174 C CB . ARG A 1 645 ? -10.570 41.495 29.660 1.00 14.21 ? 698 ARG A CB 1 ATOM 5175 C CG . ARG A 1 645 ? -11.638 41.286 30.723 1.00 14.25 ? 698 ARG A CG 1 ATOM 5176 C CD . ARG A 1 645 ? -11.845 39.824 31.108 1.00 10.87 ? 698 ARG A CD 1 ATOM 5177 N NE . ARG A 1 645 ? -12.705 39.719 32.270 1.00 12.59 ? 698 ARG A NE 1 ATOM 5178 C CZ . ARG A 1 645 ? -12.305 39.765 33.532 1.00 12.11 ? 698 ARG A CZ 1 ATOM 5179 N NH1 . ARG A 1 645 ? -11.025 39.897 33.852 1.00 13.57 ? 698 ARG A NH1 1 ATOM 5180 N NH2 . ARG A 1 645 ? -13.209 39.676 34.487 1.00 16.87 ? 698 ARG A NH2 1 ATOM 5181 N N . PRO A 1 646 ? -7.836 43.247 28.972 1.00 19.28 ? 699 PRO A N 1 ATOM 5182 C CA . PRO A 1 646 ? -6.614 43.340 28.161 1.00 19.31 ? 699 PRO A CA 1 ATOM 5183 C C . PRO A 1 646 ? -6.491 42.177 27.170 1.00 21.03 ? 699 PRO A C 1 ATOM 5184 O O . PRO A 1 646 ? -6.185 42.391 26.000 1.00 25.08 ? 699 PRO A O 1 ATOM 5185 C CB . PRO A 1 646 ? -5.481 43.309 29.200 1.00 21.31 ? 699 PRO A CB 1 ATOM 5186 C CG . PRO A 1 646 ? -6.148 43.059 30.554 1.00 22.29 ? 699 PRO A CG 1 ATOM 5187 C CD . PRO A 1 646 ? -7.584 43.434 30.411 1.00 19.85 ? 699 PRO A CD 1 ATOM 5188 N N . GLU A 1 647 ? -6.749 40.957 27.623 1.00 18.33 ? 700 GLU A N 1 ATOM 5189 C CA . GLU A 1 647 ? -6.681 39.799 26.744 1.00 18.84 ? 700 GLU A CA 1 ATOM 5190 C C . GLU A 1 647 ? -7.598 39.944 25.536 1.00 20.81 ? 700 GLU A C 1 ATOM 5191 O O . GLU A 1 647 ? -7.214 39.622 24.402 1.00 22.06 ? 700 GLU A O 1 ATOM 5192 C CB . GLU A 1 647 ? -7.053 38.526 27.505 1.00 19.55 ? 700 GLU A CB 1 ATOM 5193 C CG . GLU A 1 647 ? -6.057 38.137 28.595 1.00 19.88 ? 700 GLU A CG 1 ATOM 5194 C CD . GLU A 1 647 ? -6.440 38.682 29.960 1.00 20.07 ? 700 GLU A CD 1 ATOM 5195 O OE1 . GLU A 1 647 ? -5.886 38.202 30.970 1.00 23.22 ? 700 GLU A OE1 1 ATOM 5196 O OE2 . GLU A 1 647 ? -7.286 39.596 30.024 1.00 17.54 ? 700 GLU A OE2 1 ATOM 5197 N N . TYR A 1 648 ? -8.816 40.417 25.767 1.00 21.31 ? 701 TYR A N 1 ATOM 5198 C CA . TYR A 1 648 ? -9.767 40.566 24.675 1.00 22.53 ? 701 TYR A CA 1 ATOM 5199 C C . TYR A 1 648 ? -9.474 41.771 23.808 1.00 19.27 ? 701 TYR A C 1 ATOM 5200 O O . TYR A 1 648 ? -9.808 41.785 22.633 1.00 21.26 ? 701 TYR A O 1 ATOM 5201 C CB . TYR A 1 648 ? -11.197 40.680 25.195 1.00 25.85 ? 701 TYR A CB 1 ATOM 5202 C CG . TYR A 1 648 ? -12.205 40.704 24.069 1.00 25.94 ? 701 TYR A CG 1 ATOM 5203 C CD1 . TYR A 1 648 ? -13.046 41.788 23.887 1.00 26.81 ? 701 TYR A CD1 1 ATOM 5204 C CD2 . TYR A 1 648 ? -12.296 39.646 23.177 1.00 25.01 ? 701 TYR A CD2 1 ATOM 5205 C CE1 . TYR A 1 648 ? -13.958 41.811 22.854 1.00 27.23 ? 701 TYR A CE1 1 ATOM 5206 C CE2 . TYR A 1 648 ? -13.201 39.659 22.151 1.00 24.83 ? 701 TYR A CE2 1 ATOM 5207 C CZ . TYR A 1 648 ? -14.028 40.744 21.986 1.00 26.83 ? 701 TYR A CZ 1 ATOM 5208 O OH . TYR A 1 648 ? -14.944 40.760 20.958 1.00 29.78 ? 701 TYR A OH 1 ATOM 5209 N N . ALA A 1 649 ? -8.864 42.787 24.397 1.00 18.70 ? 702 ALA A N 1 ATOM 5210 C CA . ALA A 1 649 ? -8.498 43.983 23.653 1.00 18.98 ? 702 ALA A CA 1 ATOM 5211 C C . ALA A 1 649 ? -7.471 43.609 22.618 1.00 20.79 ? 702 ALA A C 1 ATOM 5212 O O . ALA A 1 649 ? -7.537 44.067 21.473 1.00 19.95 ? 702 ALA A O 1 ATOM 5213 C CB . ALA A 1 649 ? -7.934 45.038 24.584 1.00 17.78 ? 702 ALA A CB 1 ATOM 5214 N N . VAL A 1 650 ? -6.521 42.772 23.043 1.00 22.39 ? 703 VAL A N 1 ATOM 5215 C CA . VAL A 1 650 ? -5.517 42.184 22.158 1.00 23.00 ? 703 VAL A CA 1 ATOM 5216 C C . VAL A 1 650 ? -6.167 41.332 21.071 1.00 22.92 ? 703 VAL A C 1 ATOM 5217 O O . VAL A 1 650 ? -5.730 41.313 19.928 1.00 22.56 ? 703 VAL A O 1 ATOM 5218 C CB . VAL A 1 650 ? -4.582 41.261 22.947 1.00 23.68 ? 703 VAL A CB 1 ATOM 5219 C CG1 . VAL A 1 650 ? -3.862 40.306 22.008 1.00 24.22 ? 703 VAL A CG1 1 ATOM 5220 C CG2 . VAL A 1 650 ? -3.592 42.064 23.795 1.00 23.85 ? 703 VAL A CG2 1 ATOM 5221 N N . ASN A 1 651 ? -7.204 40.603 21.449 1.00 22.58 ? 704 ASN A N 1 ATOM 5222 C CA . ASN A 1 651 ? -7.978 39.815 20.500 1.00 19.53 ? 704 ASN A CA 1 ATOM 5223 C C . ASN A 1 651 ? -8.733 40.712 19.526 1.00 20.17 ? 704 ASN A C 1 ATOM 5224 O O . ASN A 1 651 ? -8.769 40.446 18.325 1.00 21.49 ? 704 ASN A O 1 ATOM 5225 C CB . ASN A 1 651 ? -8.954 38.931 21.268 1.00 17.99 ? 704 ASN A CB 1 ATOM 5226 C CG . ASN A 1 651 ? -9.848 38.132 20.370 1.00 17.72 ? 704 ASN A CG 1 ATOM 5227 O OD1 . ASN A 1 651 ? -10.104 38.527 19.236 1.00 14.14 ? 704 ASN A OD1 1 ATOM 5228 N ND2 . ASN A 1 651 ? -10.369 37.004 20.888 1.00 16.51 ? 704 ASN A ND2 1 ATOM 5229 N N . SER A 1 652 ? -9.341 41.771 20.043 1.00 19.65 ? 705 SER A N 1 ATOM 5230 C CA . SER A 1 652 ? -10.334 42.515 19.280 1.00 20.54 ? 705 SER A CA 1 ATOM 5231 C C . SER A 1 652 ? -9.690 43.544 18.345 1.00 19.09 ? 705 SER A C 1 ATOM 5232 O O . SER A 1 652 ? -10.232 43.855 17.281 1.00 12.78 ? 705 SER A O 1 ATOM 5233 C CB . SER A 1 652 ? -11.335 43.192 20.220 1.00 21.90 ? 705 SER A CB 1 ATOM 5234 O OG . SER A 1 652 ? -10.841 44.425 20.692 1.00 27.89 ? 705 SER A OG 1 ATOM 5235 N N . ILE A 1 653 ? -8.540 44.078 18.733 1.00 18.86 ? 706 ILE A N 1 ATOM 5236 C CA . ILE A 1 653 ? -7.867 45.064 17.900 1.00 20.21 ? 706 ILE A CA 1 ATOM 5237 C C . ILE A 1 653 ? -7.441 44.435 16.572 1.00 17.54 ? 706 ILE A C 1 ATOM 5238 O O . ILE A 1 653 ? -7.125 45.136 15.634 1.00 20.29 ? 706 ILE A O 1 ATOM 5239 C CB . ILE A 1 653 ? -6.675 45.701 18.651 1.00 19.42 ? 706 ILE A CB 1 ATOM 5240 C CG1 . ILE A 1 653 ? -6.382 47.097 18.083 1.00 20.72 ? 706 ILE A CG1 1 ATOM 5241 C CG2 . ILE A 1 653 ? -5.459 44.800 18.587 1.00 21.18 ? 706 ILE A CG2 1 ATOM 5242 C CD1 . ILE A 1 653 ? -5.166 47.793 18.709 1.00 18.81 ? 706 ILE A CD1 1 ATOM 5243 N N . LYS A 1 654 ? -7.475 43.115 16.491 1.00 20.24 ? 707 LYS A N 1 ATOM 5244 C CA . LYS A 1 654 ? -7.228 42.410 15.236 1.00 19.69 ? 707 LYS A CA 1 ATOM 5245 C C . LYS A 1 654 ? -8.491 41.830 14.601 1.00 20.60 ? 707 LYS A C 1 ATOM 5246 O O . LYS A 1 654 ? -8.524 41.593 13.398 1.00 22.53 ? 707 LYS A O 1 ATOM 5247 C CB . LYS A 1 654 ? -6.236 41.264 15.453 1.00 19.02 ? 707 LYS A CB 1 ATOM 5248 C CG . LYS A 1 654 ? -4.925 41.649 16.105 1.00 21.36 ? 707 LYS A CG 1 ATOM 5249 C CD . LYS A 1 654 ? -4.045 42.495 15.183 1.00 20.88 ? 707 LYS A CD 1 ATOM 5250 C CE . LYS A 1 654 ? -2.656 42.712 15.773 1.00 19.91 ? 707 LYS A CE 1 ATOM 5251 N NZ . LYS A 1 654 ? -2.567 43.914 16.662 1.00 23.39 ? 707 LYS A NZ 1 ATOM 5252 N N . THR A 1 655 ? -9.514 41.558 15.402 1.00 22.48 ? 708 THR A N 1 ATOM 5253 C CA . THR A 1 655 ? -10.633 40.735 14.942 1.00 24.24 ? 708 THR A CA 1 ATOM 5254 C C . THR A 1 655 ? -11.894 41.571 14.728 1.00 24.50 ? 708 THR A C 1 ATOM 5255 O O . THR A 1 655 ? -12.785 41.194 13.974 1.00 25.38 ? 708 THR A O 1 ATOM 5256 C CB . THR A 1 655 ? -10.927 39.602 15.941 1.00 22.96 ? 708 THR A CB 1 ATOM 5257 O OG1 . THR A 1 655 ? -11.054 40.138 17.265 1.00 24.06 ? 708 THR A OG1 1 ATOM 5258 C CG2 . THR A 1 655 ? -9.753 38.647 16.046 1.00 24.51 ? 708 THR A CG2 1 ATOM 5259 N N . ASP A 1 656 ? -11.983 42.702 15.406 1.00 25.16 ? 709 ASP A N 1 ATOM 5260 C CA . ASP A 1 656 ? -13.199 43.497 15.328 1.00 24.66 ? 709 ASP A CA 1 ATOM 5261 C C . ASP A 1 656 ? -13.134 44.470 14.155 1.00 23.88 ? 709 ASP A C 1 ATOM 5262 O O . ASP A 1 656 ? -12.191 45.232 14.028 1.00 23.90 ? 709 ASP A O 1 ATOM 5263 C CB . ASP A 1 656 ? -13.406 44.265 16.620 1.00 24.59 ? 709 ASP A CB 1 ATOM 5264 C CG . ASP A 1 656 ? -14.860 44.542 16.900 1.00 25.06 ? 709 ASP A CG 1 ATOM 5265 O OD1 . ASP A 1 656 ? -15.625 44.752 15.938 1.00 25.36 ? 709 ASP A OD1 1 ATOM 5266 O OD2 . ASP A 1 656 ? -15.322 44.570 18.058 1.00 28.73 ? 709 ASP A OD2 1 ATOM 5267 N N . VAL A 1 657 ? -14.154 44.465 13.312 1.00 23.49 ? 710 VAL A N 1 ATOM 5268 C CA . VAL A 1 657 ? -14.260 45.492 12.294 1.00 22.35 ? 710 VAL A CA 1 ATOM 5269 C C . VAL A 1 657 ? -14.700 46.841 12.859 1.00 20.31 ? 710 VAL A C 1 ATOM 5270 O O . VAL A 1 657 ? -14.596 47.849 12.176 1.00 20.24 ? 710 VAL A O 1 ATOM 5271 C CB . VAL A 1 657 ? -15.196 45.057 11.149 1.00 23.04 ? 710 VAL A CB 1 ATOM 5272 C CG1 . VAL A 1 657 ? -14.717 43.730 10.558 1.00 22.36 ? 710 VAL A CG1 1 ATOM 5273 C CG2 . VAL A 1 657 ? -16.638 44.982 11.621 1.00 21.49 ? 710 VAL A CG2 1 ATOM 5274 N N . HIS A 1 658 ? -15.162 46.874 14.107 1.00 21.24 ? 711 HIS A N 1 ATOM 5275 C CA . HIS A 1 658 ? -15.404 48.154 14.791 1.00 19.78 ? 711 HIS A CA 1 ATOM 5276 C C . HIS A 1 658 ? -14.164 48.657 15.520 1.00 19.54 ? 711 HIS A C 1 ATOM 5277 O O . HIS A 1 658 ? -13.347 47.867 15.984 1.00 22.24 ? 711 HIS A O 1 ATOM 5278 C CB . HIS A 1 658 ? -16.565 48.030 15.793 1.00 18.66 ? 711 HIS A CB 1 ATOM 5279 C CG . HIS A 1 658 ? -17.755 47.300 15.253 1.00 18.78 ? 711 HIS A CG 1 ATOM 5280 N ND1 . HIS A 1 658 ? -17.808 45.929 15.165 1.00 17.52 ? 711 HIS A ND1 1 ATOM 5281 C CD2 . HIS A 1 658 ? -18.940 47.753 14.775 1.00 20.16 ? 711 HIS A CD2 1 ATOM 5282 C CE1 . HIS A 1 658 ? -18.967 45.568 14.639 1.00 16.75 ? 711 HIS A CE1 1 ATOM 5283 N NE2 . HIS A 1 658 ? -19.672 46.656 14.394 1.00 15.66 ? 711 HIS A NE2 1 ATOM 5284 N N . SER A 1 659 ? -14.035 49.977 15.633 1.00 19.76 ? 712 SER A N 1 ATOM 5285 C CA . SER A 1 659 ? -13.229 50.588 16.675 1.00 18.03 ? 712 SER A CA 1 ATOM 5286 C C . SER A 1 659 ? -13.839 50.363 18.046 1.00 20.71 ? 712 SER A C 1 ATOM 5287 O O . SER A 1 659 ? -15.049 50.320 18.202 1.00 20.97 ? 712 SER A O 1 ATOM 5288 C CB . SER A 1 659 ? -13.068 52.088 16.420 1.00 18.03 ? 712 SER A CB 1 ATOM 5289 O OG . SER A 1 659 ? -12.457 52.331 15.167 1.00 16.16 ? 712 SER A OG 1 ATOM 5290 N N . PRO A 1 660 ? -12.983 50.233 19.045 1.00 20.07 ? 713 PRO A N 1 ATOM 5291 C CA . PRO A 1 660 ? -13.443 50.111 20.423 1.00 20.22 ? 713 PRO A CA 1 ATOM 5292 C C . PRO A 1 660 ? -14.277 51.322 20.812 1.00 17.80 ? 713 PRO A C 1 ATOM 5293 O O . PRO A 1 660 ? -14.037 52.413 20.317 1.00 14.76 ? 713 PRO A O 1 ATOM 5294 C CB . PRO A 1 660 ? -12.139 50.072 21.219 1.00 21.28 ? 713 PRO A CB 1 ATOM 5295 C CG . PRO A 1 660 ? -11.101 49.625 20.235 1.00 20.56 ? 713 PRO A CG 1 ATOM 5296 C CD . PRO A 1 660 ? -11.517 50.233 18.942 1.00 19.70 ? 713 PRO A CD 1 ATOM 5297 N N . GLY A 1 661 ? -15.250 51.128 21.688 1.00 19.42 ? 714 GLY A N 1 ATOM 5298 C CA . GLY A 1 661 ? -16.286 52.128 21.886 1.00 20.19 ? 714 GLY A CA 1 ATOM 5299 C C . GLY A 1 661 ? -15.737 53.506 22.182 1.00 17.69 ? 714 GLY A C 1 ATOM 5300 O O . GLY A 1 661 ? -16.227 54.509 21.670 1.00 17.54 ? 714 GLY A O 1 ATOM 5301 N N . ASN A 1 662 ? -14.721 53.570 23.028 1.00 18.83 ? 715 ASN A N 1 ATOM 5302 C CA . ASN A 1 662 ? -14.177 54.860 23.408 1.00 20.00 ? 715 ASN A CA 1 ATOM 5303 C C . ASN A 1 662 ? -13.613 55.639 22.213 1.00 19.49 ? 715 ASN A C 1 ATOM 5304 O O . ASN A 1 662 ? -13.788 56.850 22.126 1.00 17.09 ? 715 ASN A O 1 ATOM 5305 C CB . ASN A 1 662 ? -13.124 54.698 24.512 1.00 21.73 ? 715 ASN A CB 1 ATOM 5306 C CG . ASN A 1 662 ? -11.897 53.986 24.043 1.00 22.83 ? 715 ASN A CG 1 ATOM 5307 O OD1 . ASN A 1 662 ? -11.980 52.942 23.398 1.00 25.34 ? 715 ASN A OD1 1 ATOM 5308 N ND2 . ASN A 1 662 ? -10.734 54.544 24.363 1.00 22.58 ? 715 ASN A ND2 1 ATOM 5309 N N . PHE A 1 663 ? -12.943 54.958 21.290 1.00 18.38 ? 716 PHE A N 1 ATOM 5310 C CA . PHE A 1 663 ? -12.375 55.653 20.139 1.00 19.70 ? 716 PHE A CA 1 ATOM 5311 C C . PHE A 1 663 ? -13.441 55.967 19.079 1.00 21.46 ? 716 PHE A C 1 ATOM 5312 O O . PHE A 1 663 ? -13.235 56.830 18.221 1.00 18.26 ? 716 PHE A O 1 ATOM 5313 C CB . PHE A 1 663 ? -11.205 54.856 19.536 1.00 23.04 ? 716 PHE A CB 1 ATOM 5314 C CG . PHE A 1 663 ? -10.001 54.770 20.450 1.00 19.46 ? 716 PHE A CG 1 ATOM 5315 C CD1 . PHE A 1 663 ? -9.602 53.569 20.978 1.00 20.88 ? 716 PHE A CD1 1 ATOM 5316 C CD2 . PHE A 1 663 ? -9.312 55.898 20.799 1.00 21.70 ? 716 PHE A CD2 1 ATOM 5317 C CE1 . PHE A 1 663 ? -8.525 53.494 21.820 1.00 22.17 ? 716 PHE A CE1 1 ATOM 5318 C CE2 . PHE A 1 663 ? -8.246 55.833 21.654 1.00 22.42 ? 716 PHE A CE2 1 ATOM 5319 C CZ . PHE A 1 663 ? -7.846 54.629 22.160 1.00 23.17 ? 716 PHE A CZ 1 ATOM 5320 N N . ARG A 1 664 ? -14.594 55.307 19.155 1.00 17.04 ? 717 ARG A N 1 ATOM 5321 C CA . ARG A 1 664 ? -15.713 55.706 18.319 1.00 21.76 ? 717 ARG A CA 1 ATOM 5322 C C . ARG A 1 664 ? -16.291 57.049 18.760 1.00 21.16 ? 717 ARG A C 1 ATOM 5323 O O . ARG A 1 664 ? -16.469 57.949 17.950 1.00 20.55 ? 717 ARG A O 1 ATOM 5324 C CB . ARG A 1 664 ? -16.788 54.631 18.317 1.00 21.77 ? 717 ARG A CB 1 ATOM 5325 C CG . ARG A 1 664 ? -16.288 53.304 17.803 1.00 22.02 ? 717 ARG A CG 1 ATOM 5326 C CD . ARG A 1 664 ? -17.313 52.213 17.856 1.00 21.14 ? 717 ARG A CD 1 ATOM 5327 N NE . ARG A 1 664 ? -18.319 52.393 16.829 1.00 21.68 ? 717 ARG A NE 1 ATOM 5328 C CZ . ARG A 1 664 ? -19.114 51.431 16.418 1.00 21.78 ? 717 ARG A CZ 1 ATOM 5329 N NH1 . ARG A 1 664 ? -19.019 50.221 16.955 1.00 24.98 ? 717 ARG A NH1 1 ATOM 5330 N NH2 . ARG A 1 664 ? -20.013 51.679 15.480 1.00 18.10 ? 717 ARG A NH2 1 ATOM 5331 N N . ILE A 1 665 ? -16.552 57.192 20.051 1.00 23.67 ? 718 ILE A N 1 ATOM 5332 C CA . ILE A 1 665 ? -16.936 58.482 20.587 1.00 24.22 ? 718 ILE A CA 1 ATOM 5333 C C . ILE A 1 665 ? -15.940 59.548 20.136 1.00 23.62 ? 718 ILE A C 1 ATOM 5334 O O . ILE A 1 665 ? -16.330 60.557 19.564 1.00 23.77 ? 718 ILE A O 1 ATOM 5335 C CB . ILE A 1 665 ? -17.017 58.443 22.116 1.00 26.16 ? 718 ILE A CB 1 ATOM 5336 C CG1 . ILE A 1 665 ? -18.066 57.428 22.570 1.00 29.21 ? 718 ILE A CG1 1 ATOM 5337 C CG2 . ILE A 1 665 ? -17.384 59.820 22.659 1.00 25.38 ? 718 ILE A CG2 1 ATOM 5338 C CD1 . ILE A 1 665 ? -17.915 56.063 21.924 1.00 32.52 ? 718 ILE A CD1 1 ATOM 5339 N N . ILE A 1 666 ? -14.660 59.321 20.403 1.00 23.42 ? 719 ILE A N 1 ATOM 5340 C CA . ILE A 1 666 ? -13.649 60.356 20.232 1.00 25.66 ? 719 ILE A CA 1 ATOM 5341 C C . ILE A 1 666 ? -13.325 60.565 18.750 1.00 27.26 ? 719 ILE A C 1 ATOM 5342 O O . ILE A 1 666 ? -13.220 61.700 18.281 1.00 28.45 ? 719 ILE A O 1 ATOM 5343 C CB . ILE A 1 666 ? -12.384 59.979 20.998 1.00 27.55 ? 719 ILE A CB 1 ATOM 5344 C CG1 . ILE A 1 666 ? -12.603 60.173 22.496 1.00 28.10 ? 719 ILE A CG1 1 ATOM 5345 C CG2 . ILE A 1 666 ? -11.209 60.818 20.530 1.00 27.49 ? 719 ILE A CG2 1 ATOM 5346 C CD1 . ILE A 1 666 ? -11.484 59.640 23.315 1.00 30.80 ? 719 ILE A CD1 1 ATOM 5347 N N . GLY A 1 667 ? -13.188 59.460 18.019 1.00 26.83 ? 720 GLY A N 1 ATOM 5348 C CA . GLY A 1 667 ? -13.083 59.494 16.572 1.00 26.03 ? 720 GLY A CA 1 ATOM 5349 C C . GLY A 1 667 ? -14.048 60.467 15.928 1.00 25.25 ? 720 GLY A C 1 ATOM 5350 O O . GLY A 1 667 ? -13.629 61.373 15.184 1.00 21.53 ? 720 GLY A O 1 ATOM 5351 N N . THR A 1 668 ? -15.338 60.285 16.206 1.00 23.28 ? 721 THR A N 1 ATOM 5352 C CA . THR A 1 668 ? -16.379 60.898 15.392 1.00 25.02 ? 721 THR A CA 1 ATOM 5353 C C . THR A 1 668 ? -16.578 62.347 15.792 1.00 23.88 ? 721 THR A C 1 ATOM 5354 O O . THR A 1 668 ? -16.734 63.201 14.936 1.00 24.79 ? 721 THR A O 1 ATOM 5355 C CB . THR A 1 668 ? -17.716 60.124 15.494 1.00 26.40 ? 721 THR A CB 1 ATOM 5356 O OG1 . THR A 1 668 ? -18.294 60.312 16.793 1.00 34.56 ? 721 THR A OG1 1 ATOM 5357 C CG2 . THR A 1 668 ? -17.487 58.616 15.407 1.00 25.88 ? 721 THR A CG2 1 ATOM 5358 N N . LEU A 1 669 ? -16.557 62.621 17.092 1.00 24.03 ? 722 LEU A N 1 ATOM 5359 C CA . LEU A 1 669 ? -16.750 63.978 17.600 1.00 25.04 ? 722 LEU A CA 1 ATOM 5360 C C . LEU A 1 669 ? -15.618 64.948 17.266 1.00 26.40 ? 722 LEU A C 1 ATOM 5361 O O . LEU A 1 669 ? -15.845 66.150 17.137 1.00 29.44 ? 722 LEU A O 1 ATOM 5362 C CB . LEU A 1 669 ? -16.959 63.933 19.109 1.00 24.72 ? 722 LEU A CB 1 ATOM 5363 C CG . LEU A 1 669 ? -18.195 63.137 19.501 1.00 24.32 ? 722 LEU A CG 1 ATOM 5364 C CD1 . LEU A 1 669 ? -18.349 63.074 21.008 1.00 24.39 ? 722 LEU A CD1 1 ATOM 5365 C CD2 . LEU A 1 669 ? -19.414 63.752 18.847 1.00 23.79 ? 722 LEU A CD2 1 ATOM 5366 N N . GLN A 1 670 ? -14.407 64.435 17.127 1.00 27.55 ? 723 GLN A N 1 ATOM 5367 C CA . GLN A 1 670 ? -13.314 65.252 16.625 1.00 28.45 ? 723 GLN A CA 1 ATOM 5368 C C . GLN A 1 670 ? -13.581 65.705 15.188 1.00 28.67 ? 723 GLN A C 1 ATOM 5369 O O . GLN A 1 670 ? -13.192 66.806 14.793 1.00 31.36 ? 723 GLN A O 1 ATOM 5370 C CB . GLN A 1 670 ? -12.001 64.483 16.718 1.00 27.57 ? 723 GLN A CB 1 ATOM 5371 C CG . GLN A 1 670 ? -11.464 64.377 18.140 1.00 25.10 ? 723 GLN A CG 1 ATOM 5372 C CD . GLN A 1 670 ? -10.206 63.527 18.229 1.00 24.92 ? 723 GLN A CD 1 ATOM 5373 O OE1 . GLN A 1 670 ? -9.942 62.712 17.345 1.00 21.39 ? 723 GLN A OE1 1 ATOM 5374 N NE2 . GLN A 1 670 ? -9.437 63.705 19.305 1.00 23.35 ? 723 GLN A NE2 1 ATOM 5375 N N . ASN A 1 671 ? -14.269 64.868 14.424 1.00 26.57 ? 724 ASN A N 1 ATOM 5376 C CA . ASN A 1 671 ? -14.594 65.197 13.042 1.00 26.79 ? 724 ASN A CA 1 ATOM 5377 C C . ASN A 1 671 ? -15.861 66.036 12.916 1.00 26.26 ? 724 ASN A C 1 ATOM 5378 O O . ASN A 1 671 ? -16.247 66.412 11.823 1.00 29.13 ? 724 ASN A O 1 ATOM 5379 C CB . ASN A 1 671 ? -14.737 63.926 12.215 1.00 25.31 ? 724 ASN A CB 1 ATOM 5380 C CG . ASN A 1 671 ? -13.422 63.185 12.058 1.00 25.41 ? 724 ASN A CG 1 ATOM 5381 O OD1 . ASN A 1 671 ? -12.359 63.793 12.022 1.00 24.77 ? 724 ASN A OD1 1 ATOM 5382 N ND2 . ASN A 1 671 ? -13.490 61.867 11.975 1.00 26.82 ? 724 ASN A ND2 1 ATOM 5383 N N . SER A 1 672 ? -16.509 66.332 14.035 1.00 29.08 ? 725 SER A N 1 ATOM 5384 C CA . SER A 1 672 ? -17.810 66.984 13.988 1.00 29.18 ? 725 SER A CA 1 ATOM 5385 C C . SER A 1 672 ? -17.715 68.406 14.519 1.00 29.04 ? 725 SER A C 1 ATOM 5386 O O . SER A 1 672 ? -17.391 68.623 15.673 1.00 28.30 ? 725 SER A O 1 ATOM 5387 C CB . SER A 1 672 ? -18.844 66.185 14.783 1.00 28.19 ? 725 SER A CB 1 ATOM 5388 O OG . SER A 1 672 ? -19.960 66.990 15.111 1.00 26.73 ? 725 SER A OG 1 ATOM 5389 N N . ALA A 1 673 ? -18.000 69.374 13.657 1.00 31.62 ? 726 ALA A N 1 ATOM 5390 C CA . ALA A 1 673 ? -18.070 70.763 14.072 1.00 30.78 ? 726 ALA A CA 1 ATOM 5391 C C . ALA A 1 673 ? -19.260 71.000 14.994 1.00 28.98 ? 726 ALA A C 1 ATOM 5392 O O . ALA A 1 673 ? -19.171 71.782 15.937 1.00 28.92 ? 726 ALA A O 1 ATOM 5393 C CB . ALA A 1 673 ? -18.137 71.682 12.847 1.00 32.07 ? 726 ALA A CB 1 ATOM 5394 N N . GLU A 1 674 ? -20.367 70.314 14.738 1.00 31.32 ? 727 GLU A N 1 ATOM 5395 C CA . GLU A 1 674 ? -21.589 70.527 15.524 1.00 32.14 ? 727 GLU A CA 1 ATOM 5396 C C . GLU A 1 674 ? -21.319 70.294 17.000 1.00 29.40 ? 727 GLU A C 1 ATOM 5397 O O . GLU A 1 674 ? -21.733 71.079 17.851 1.00 28.97 ? 727 GLU A O 1 ATOM 5398 C CB . GLU A 1 674 ? -22.703 69.594 15.064 1.00 35.32 ? 727 GLU A CB 1 ATOM 5399 C CG . GLU A 1 674 ? -23.317 69.964 13.722 1.00 38.30 ? 727 GLU A CG 1 ATOM 5400 C CD . GLU A 1 674 ? -22.278 70.101 12.628 1.00 39.13 ? 727 GLU A CD 1 ATOM 5401 O OE1 . GLU A 1 674 ? -21.508 69.142 12.412 1.00 39.56 ? 727 GLU A OE1 1 ATOM 5402 O OE2 . GLU A 1 674 ? -22.234 71.174 11.992 1.00 42.69 ? 727 GLU A OE2 1 ATOM 5403 N N . PHE A 1 675 ? -20.605 69.215 17.297 1.00 26.62 ? 728 PHE A N 1 ATOM 5404 C CA . PHE A 1 675 ? -20.303 68.865 18.676 1.00 27.88 ? 728 PHE A CA 1 ATOM 5405 C C . PHE A 1 675 ? -19.612 70.019 19.386 1.00 30.65 ? 728 PHE A C 1 ATOM 5406 O O . PHE A 1 675 ? -20.017 70.417 20.475 1.00 31.97 ? 728 PHE A O 1 ATOM 5407 C CB . PHE A 1 675 ? -19.412 67.632 18.738 1.00 27.68 ? 728 PHE A CB 1 ATOM 5408 C CG . PHE A 1 675 ? -18.837 67.389 20.096 1.00 27.27 ? 728 PHE A CG 1 ATOM 5409 C CD1 . PHE A 1 675 ? -17.568 67.841 20.416 1.00 27.47 ? 728 PHE A CD1 1 ATOM 5410 C CD2 . PHE A 1 675 ? -19.570 66.721 21.056 1.00 24.65 ? 728 PHE A CD2 1 ATOM 5411 C CE1 . PHE A 1 675 ? -17.050 67.633 21.665 1.00 28.38 ? 728 PHE A CE1 1 ATOM 5412 C CE2 . PHE A 1 675 ? -19.053 66.508 22.302 1.00 27.35 ? 728 PHE A CE2 1 ATOM 5413 C CZ . PHE A 1 675 ? -17.790 66.964 22.614 1.00 27.90 ? 728 PHE A CZ 1 ATOM 5414 N N . SER A 1 676 ? -18.570 70.549 18.752 1.00 31.41 ? 729 SER A N 1 ATOM 5415 C CA . SER A 1 676 ? -17.724 71.571 19.353 1.00 32.00 ? 729 SER A CA 1 ATOM 5416 C C . SER A 1 676 ? -18.466 72.897 19.496 1.00 34.49 ? 729 SER A C 1 ATOM 5417 O O . SER A 1 676 ? -18.111 73.719 20.342 1.00 35.91 ? 729 SER A O 1 ATOM 5418 C CB . SER A 1 676 ? -16.474 71.784 18.501 1.00 31.07 ? 729 SER A CB 1 ATOM 5419 O OG . SER A 1 676 ? -15.404 70.985 18.963 1.00 29.86 ? 729 SER A OG 1 ATOM 5420 N N . GLU A 1 677 ? -19.486 73.098 18.664 1.00 34.73 ? 730 GLU A N 1 ATOM 5421 C CA . GLU A 1 677 ? -20.450 74.172 18.856 1.00 36.73 ? 730 GLU A CA 1 ATOM 5422 C C . GLU A 1 677 ? -21.365 73.871 20.034 1.00 36.10 ? 730 GLU A C 1 ATOM 5423 O O . GLU A 1 677 ? -21.840 74.775 20.709 1.00 34.77 ? 730 GLU A O 1 ATOM 5424 C CB . GLU A 1 677 ? -21.282 74.352 17.586 1.00 39.28 ? 730 GLU A CB 1 ATOM 5425 C CG . GLU A 1 677 ? -22.128 75.614 17.563 1.00 44.36 ? 730 GLU A CG 1 ATOM 5426 C CD . GLU A 1 677 ? -23.543 75.390 18.088 1.00 48.10 ? 730 GLU A CD 1 ATOM 5427 O OE1 . GLU A 1 677 ? -24.442 74.994 17.305 1.00 52.06 ? 730 GLU A OE1 1 ATOM 5428 O OE2 . GLU A 1 677 ? -23.764 75.620 19.296 1.00 50.30 ? 730 GLU A OE2 1 ATOM 5429 N N . ALA A 1 678 ? -21.626 72.594 20.274 1.00 36.34 ? 731 ALA A N 1 ATOM 5430 C CA . ALA A 1 678 ? -22.467 72.215 21.393 1.00 36.94 ? 731 ALA A CA 1 ATOM 5431 C C . ALA A 1 678 ? -21.751 72.514 22.704 1.00 34.88 ? 731 ALA A C 1 ATOM 5432 O O . ALA A 1 678 ? -22.352 73.044 23.631 1.00 37.58 ? 731 ALA A O 1 ATOM 5433 C CB . ALA A 1 678 ? -22.842 70.752 21.301 1.00 38.43 ? 731 ALA A CB 1 ATOM 5434 N N . PHE A 1 679 ? -20.460 72.207 22.768 1.00 33.47 ? 732 PHE A N 1 ATOM 5435 C CA . PHE A 1 679 ? -19.713 72.345 24.016 1.00 34.01 ? 732 PHE A CA 1 ATOM 5436 C C . PHE A 1 679 ? -18.623 73.411 23.948 1.00 35.77 ? 732 PHE A C 1 ATOM 5437 O O . PHE A 1 679 ? -17.657 73.384 24.713 1.00 34.62 ? 732 PHE A O 1 ATOM 5438 C CB . PHE A 1 679 ? -19.119 70.997 24.414 1.00 32.18 ? 732 PHE A CB 1 ATOM 5439 C CG . PHE A 1 679 ? -20.156 69.941 24.641 1.00 31.79 ? 732 PHE A CG 1 ATOM 5440 C CD1 . PHE A 1 679 ? -20.689 69.735 25.902 1.00 30.31 ? 732 PHE A CD1 1 ATOM 5441 C CD2 . PHE A 1 679 ? -20.627 69.175 23.583 1.00 32.18 ? 732 PHE A CD2 1 ATOM 5442 C CE1 . PHE A 1 679 ? -21.653 68.768 26.112 1.00 29.28 ? 732 PHE A CE1 1 ATOM 5443 C CE2 . PHE A 1 679 ? -21.595 68.213 23.792 1.00 31.20 ? 732 PHE A CE2 1 ATOM 5444 C CZ . PHE A 1 679 ? -22.107 68.014 25.062 1.00 29.43 ? 732 PHE A CZ 1 ATOM 5445 N N . HIS A 1 680 ? -18.792 74.365 23.040 1.00 37.34 ? 733 HIS A N 1 ATOM 5446 C CA . HIS A 1 680 ? -17.971 75.565 23.057 1.00 39.20 ? 733 HIS A CA 1 ATOM 5447 C C . HIS A 1 680 ? -16.504 75.170 23.203 1.00 38.75 ? 733 HIS A C 1 ATOM 5448 O O . HIS A 1 680 ? -15.792 75.657 24.072 1.00 41.62 ? 733 HIS A O 1 ATOM 5449 C CB . HIS A 1 680 ? -18.429 76.492 24.185 1.00 39.53 ? 733 HIS A CB 1 ATOM 5450 C CG . HIS A 1 680 ? -19.916 76.673 24.238 1.00 42.08 ? 733 HIS A CG 1 ATOM 5451 N ND1 . HIS A 1 680 ? -20.727 75.944 25.081 1.00 43.19 ? 733 HIS A ND1 1 ATOM 5452 C CD2 . HIS A 1 680 ? -20.741 77.482 23.531 1.00 44.49 ? 733 HIS A CD2 1 ATOM 5453 C CE1 . HIS A 1 680 ? -21.985 76.306 24.902 1.00 43.45 ? 733 HIS A CE1 1 ATOM 5454 N NE2 . HIS A 1 680 ? -22.022 77.234 23.963 1.00 44.10 ? 733 HIS A NE2 1 ATOM 5455 N N . CYS A 1 681 ? -16.060 74.275 22.333 1.00 39.50 ? 734 CYS A N 1 ATOM 5456 C CA . CYS A 1 681 ? -14.694 73.780 22.376 1.00 40.09 ? 734 CYS A CA 1 ATOM 5457 C C . CYS A 1 681 ? -13.748 74.747 21.668 1.00 43.23 ? 734 CYS A C 1 ATOM 5458 O O . CYS A 1 681 ? -14.042 75.234 20.575 1.00 44.27 ? 734 CYS A O 1 ATOM 5459 C CB . CYS A 1 681 ? -14.624 72.393 21.733 1.00 38.77 ? 734 CYS A CB 1 ATOM 5460 S SG . CYS A 1 681 ? -15.587 71.141 22.623 1.00 37.28 ? 734 CYS A SG 1 ATOM 5461 N N . ARG A 1 682 ? -12.617 75.028 22.307 1.00 44.92 ? 735 ARG A N 1 ATOM 5462 C CA . ARG A 1 682 ? -11.607 75.895 21.731 1.00 46.78 ? 735 ARG A CA 1 ATOM 5463 C C . ARG A 1 682 ? -11.074 75.238 20.476 1.00 46.26 ? 735 ARG A C 1 ATOM 5464 O O . ARG A 1 682 ? -10.974 74.011 20.398 1.00 43.21 ? 735 ARG A O 1 ATOM 5465 C CB . ARG A 1 682 ? -10.465 76.137 22.724 1.00 49.85 ? 735 ARG A CB 1 ATOM 5466 C CG . ARG A 1 682 ? -10.728 77.271 23.716 1.00 53.41 ? 735 ARG A CG 1 ATOM 5467 C CD . ARG A 1 682 ? -9.727 77.344 24.874 1.00 56.10 ? 735 ARG A CD 1 ATOM 5468 N NE . ARG A 1 682 ? -8.627 78.269 24.599 1.00 59.05 ? 735 ARG A NE 1 ATOM 5469 C CZ . ARG A 1 682 ? -7.830 78.796 25.529 1.00 60.06 ? 735 ARG A CZ 1 ATOM 5470 N NH1 . ARG A 1 682 ? -8.003 78.495 26.811 1.00 60.26 ? 735 ARG A NH1 1 ATOM 5471 N NH2 . ARG A 1 682 ? -6.858 79.630 25.174 1.00 59.15 ? 735 ARG A NH2 1 ATOM 5472 N N . LYS A 1 683 ? -10.731 76.056 19.490 1.00 45.01 ? 736 LYS A N 1 ATOM 5473 C CA . LYS A 1 683 ? -9.828 75.617 18.444 1.00 44.70 ? 736 LYS A CA 1 ATOM 5474 C C . LYS A 1 683 ? -8.692 74.828 19.085 1.00 42.22 ? 736 LYS A C 1 ATOM 5475 O O . LYS A 1 683 ? -7.933 75.359 19.894 1.00 41.45 ? 736 LYS A O 1 ATOM 5476 C CB . LYS A 1 683 ? -9.290 76.817 17.659 1.00 47.64 ? 736 LYS A CB 1 ATOM 5477 C CG . LYS A 1 683 ? -10.134 78.087 17.784 1.00 49.58 ? 736 LYS A CG 1 ATOM 5478 C CD . LYS A 1 683 ? -9.352 79.322 17.338 1.00 51.06 ? 736 LYS A CD 1 ATOM 5479 C CE . LYS A 1 683 ? -8.672 80.027 18.510 1.00 51.68 ? 736 LYS A CE 1 ATOM 5480 N NZ . LYS A 1 683 ? -9.153 81.431 18.687 1.00 51.86 ? 736 LYS A NZ 1 ATOM 5481 N N . ASN A 1 684 ? -8.592 73.550 18.735 1.00 39.89 ? 737 ASN A N 1 ATOM 5482 C CA . ASN A 1 684 ? -7.380 72.785 18.971 1.00 37.72 ? 737 ASN A CA 1 ATOM 5483 C C . ASN A 1 684 ? -7.375 72.102 20.335 1.00 36.11 ? 737 ASN A C 1 ATOM 5484 O O . ASN A 1 684 ? -6.395 71.448 20.704 1.00 35.41 ? 737 ASN A O 1 ATOM 5485 C CB . ASN A 1 684 ? -6.163 73.697 18.854 1.00 39.37 ? 737 ASN A CB 1 ATOM 5486 C CG . ASN A 1 684 ? -5.666 73.817 17.435 1.00 42.66 ? 737 ASN A CG 1 ATOM 5487 O OD1 . ASN A 1 684 ? -5.782 72.881 16.645 1.00 42.83 ? 737 ASN A OD1 1 ATOM 5488 N ND2 . ASN A 1 684 ? -5.111 74.975 17.097 1.00 45.33 ? 737 ASN A ND2 1 ATOM 5489 N N . SER A 1 685 ? -8.464 72.267 21.081 1.00 32.18 ? 738 SER A N 1 ATOM 5490 C CA . SER A 1 685 ? -8.824 71.338 22.148 1.00 32.06 ? 738 SER A CA 1 ATOM 5491 C C . SER A 1 685 ? -8.813 69.906 21.655 1.00 28.25 ? 738 SER A C 1 ATOM 5492 O O . SER A 1 685 ? -9.049 69.641 20.482 1.00 27.47 ? 738 SER A O 1 ATOM 5493 C CB . SER A 1 685 ? -10.216 71.662 22.687 1.00 31.60 ? 738 SER A CB 1 ATOM 5494 O OG . SER A 1 685 ? -11.200 71.227 21.774 1.00 30.74 ? 738 SER A OG 1 ATOM 5495 N N . TYR A 1 686 ? -8.544 68.973 22.555 1.00 29.24 ? 739 TYR A N 1 ATOM 5496 C CA . TYR A 1 686 ? -8.342 67.595 22.134 1.00 27.77 ? 739 TYR A CA 1 ATOM 5497 C C . TYR A 1 686 ? -9.525 67.111 21.285 1.00 29.21 ? 739 TYR A C 1 ATOM 5498 O O . TYR A 1 686 ? -9.329 66.420 20.283 1.00 30.36 ? 739 TYR A O 1 ATOM 5499 C CB . TYR A 1 686 ? -8.097 66.670 23.331 1.00 27.78 ? 739 TYR A CB 1 ATOM 5500 C CG . TYR A 1 686 ? -7.915 65.232 22.903 1.00 26.82 ? 739 TYR A CG 1 ATOM 5501 C CD1 . TYR A 1 686 ? -8.911 64.285 23.128 1.00 25.53 ? 739 TYR A CD1 1 ATOM 5502 C CD2 . TYR A 1 686 ? -6.769 64.835 22.227 1.00 25.28 ? 739 TYR A CD2 1 ATOM 5503 C CE1 . TYR A 1 686 ? -8.756 62.970 22.703 1.00 25.65 ? 739 TYR A CE1 1 ATOM 5504 C CE2 . TYR A 1 686 ? -6.605 63.535 21.795 1.00 24.86 ? 739 TYR A CE2 1 ATOM 5505 C CZ . TYR A 1 686 ? -7.603 62.605 22.040 1.00 26.63 ? 739 TYR A CZ 1 ATOM 5506 O OH . TYR A 1 686 ? -7.445 61.314 21.616 1.00 26.57 ? 739 TYR A OH 1 ATOM 5507 N N . MET A 1 687 ? -10.745 67.483 21.671 1.00 29.55 ? 740 MET A N 1 ATOM 5508 C CA . MET A 1 687 ? -11.942 67.028 20.953 1.00 29.20 ? 740 MET A CA 1 ATOM 5509 C C . MET A 1 687 ? -12.187 67.812 19.663 1.00 32.32 ? 740 MET A C 1 ATOM 5510 O O . MET A 1 687 ? -13.091 67.481 18.887 1.00 33.03 ? 740 MET A O 1 ATOM 5511 C CB . MET A 1 687 ? -13.191 67.152 21.837 1.00 26.78 ? 740 MET A CB 1 ATOM 5512 C CG . MET A 1 687 ? -13.208 66.240 23.053 1.00 26.32 ? 740 MET A CG 1 ATOM 5513 S SD . MET A 1 687 ? -12.771 64.545 22.694 1.00 25.07 ? 740 MET A SD 1 ATOM 5514 C CE . MET A 1 687 ? -14.111 64.086 21.578 1.00 22.34 ? 740 MET A CE 1 ATOM 5515 N N . ASN A 1 688 ? -11.413 68.869 19.448 1.00 33.22 ? 741 ASN A N 1 ATOM 5516 C CA . ASN A 1 688 ? -11.675 69.785 18.342 1.00 33.64 ? 741 ASN A CA 1 ATOM 5517 C C . ASN A 1 688 ? -10.412 70.140 17.560 1.00 33.34 ? 741 ASN A C 1 ATOM 5518 O O . ASN A 1 688 ? -9.963 71.286 17.578 1.00 32.03 ? 741 ASN A O 1 ATOM 5519 C CB . ASN A 1 688 ? -12.328 71.067 18.861 1.00 33.39 ? 741 ASN A CB 1 ATOM 5520 C CG . ASN A 1 688 ? -12.783 71.989 17.736 1.00 32.76 ? 741 ASN A CG 1 ATOM 5521 O OD1 . ASN A 1 688 ? -12.727 71.627 16.561 1.00 32.40 ? 741 ASN A OD1 1 ATOM 5522 N ND2 . ASN A 1 688 ? -13.240 73.188 18.097 1.00 33.58 ? 741 ASN A ND2 1 ATOM 5523 N N . PRO A 1 689 ? -9.861 69.164 16.851 1.00 32.22 ? 742 PRO A N 1 ATOM 5524 C CA . PRO A 1 689 ? -8.754 69.423 15.928 1.00 33.64 ? 742 PRO A CA 1 ATOM 5525 C C . PRO A 1 689 ? -9.199 70.313 14.770 1.00 35.74 ? 742 PRO A C 1 ATOM 5526 O O . PRO A 1 689 ? -10.318 70.173 14.290 1.00 35.39 ? 742 PRO A O 1 ATOM 5527 C CB . PRO A 1 689 ? -8.378 68.027 15.425 1.00 33.15 ? 742 PRO A CB 1 ATOM 5528 C CG . PRO A 1 689 ? -9.607 67.198 15.629 1.00 33.91 ? 742 PRO A CG 1 ATOM 5529 C CD . PRO A 1 689 ? -10.278 67.751 16.851 1.00 32.96 ? 742 PRO A CD 1 ATOM 5530 N N . GLU A 1 690 ? -8.327 71.214 14.327 1.00 39.41 ? 743 GLU A N 1 ATOM 5531 C CA . GLU A 1 690 ? -8.623 72.054 13.177 1.00 39.76 ? 743 GLU A CA 1 ATOM 5532 C C . GLU A 1 690 ? -8.766 71.179 11.947 1.00 38.08 ? 743 GLU A C 1 ATOM 5533 O O . GLU A 1 690 ? -9.590 71.449 11.075 1.00 35.74 ? 743 GLU A O 1 ATOM 5534 C CB . GLU A 1 690 ? -7.509 73.084 12.964 1.00 43.93 ? 743 GLU A CB 1 ATOM 5535 C CG . GLU A 1 690 ? -7.805 74.117 11.881 1.00 46.77 ? 743 GLU A CG 1 ATOM 5536 C CD . GLU A 1 690 ? -7.424 73.640 10.488 1.00 49.71 ? 743 GLU A CD 1 ATOM 5537 O OE1 . GLU A 1 690 ? -6.515 72.781 10.380 1.00 52.20 ? 743 GLU A OE1 1 ATOM 5538 O OE2 . GLU A 1 690 ? -8.032 74.121 9.501 1.00 50.22 ? 743 GLU A OE2 1 ATOM 5539 N N . LYS A 1 691 ? -7.958 70.124 11.887 1.00 37.00 ? 744 LYS A N 1 ATOM 5540 C CA . LYS A 1 691 ? -8.019 69.168 10.789 1.00 37.67 ? 744 LYS A CA 1 ATOM 5541 C C . LYS A 1 691 ? -9.065 68.081 11.032 1.00 37.25 ? 744 LYS A C 1 ATOM 5542 O O . LYS A 1 691 ? -9.002 67.352 12.036 1.00 37.33 ? 744 LYS A O 1 ATOM 5543 C CB . LYS A 1 691 ? -6.647 68.515 10.581 1.00 38.10 ? 744 LYS A CB 1 ATOM 5544 C CG . LYS A 1 691 ? -6.346 68.193 9.124 1.00 39.83 ? 744 LYS A CG 1 ATOM 5545 C CD . LYS A 1 691 ? -6.297 66.691 8.873 1.00 39.33 ? 744 LYS A CD 1 ATOM 5546 C CE . LYS A 1 691 ? -5.777 66.375 7.476 1.00 39.06 ? 744 LYS A CE 1 ATOM 5547 N NZ . LYS A 1 691 ? -6.863 66.029 6.508 1.00 36.23 ? 744 LYS A NZ 1 ATOM 5548 N N . LYS A 1 692 ? -10.016 67.968 10.106 1.00 34.37 ? 745 LYS A N 1 ATOM 5549 C CA . LYS A 1 692 ? -11.162 67.083 10.288 1.00 33.21 ? 745 LYS A CA 1 ATOM 5550 C C . LYS A 1 692 ? -11.452 66.246 9.055 1.00 30.95 ? 745 LYS A C 1 ATOM 5551 O O . LYS A 1 692 ? -11.315 66.702 7.922 1.00 29.98 ? 745 LYS A O 1 ATOM 5552 C CB . LYS A 1 692 ? -12.407 67.878 10.679 1.00 33.79 ? 745 LYS A CB 1 ATOM 5553 C CG . LYS A 1 692 ? -12.353 68.396 12.102 1.00 34.72 ? 745 LYS A CG 1 ATOM 5554 C CD . LYS A 1 692 ? -13.737 68.551 12.707 1.00 35.33 ? 745 LYS A CD 1 ATOM 5555 C CE . LYS A 1 692 ? -13.877 69.875 13.425 1.00 32.78 ? 745 LYS A CE 1 ATOM 5556 N NZ . LYS A 1 692 ? -12.973 69.970 14.599 1.00 33.47 ? 745 LYS A NZ 1 ATOM 5557 N N . CYS A 1 693 ? -11.843 65.005 9.294 1.00 27.20 ? 746 CYS A N 1 ATOM 5558 C CA . CYS A 1 693 ? -12.150 64.089 8.220 1.00 27.15 ? 746 CYS A CA 1 ATOM 5559 C C . CYS A 1 693 ? -13.620 64.195 7.893 1.00 23.58 ? 746 CYS A C 1 ATOM 5560 O O . CYS A 1 693 ? -14.440 64.447 8.758 1.00 26.90 ? 746 CYS A O 1 ATOM 5561 C CB . CYS A 1 693 ? -11.813 62.655 8.624 1.00 28.73 ? 746 CYS A CB 1 ATOM 5562 S SG . CYS A 1 693 ? -10.098 62.418 9.119 1.00 28.82 ? 746 CYS A SG 1 ATOM 5563 N N . ARG A 1 694 ? -13.938 64.019 6.626 1.00 22.54 ? 747 ARG A N 1 ATOM 5564 C CA . ARG A 1 694 ? -15.300 63.945 6.182 1.00 23.62 ? 747 ARG A CA 1 ATOM 5565 C C . ARG A 1 694 ? -15.328 63.127 4.919 1.00 25.42 ? 747 ARG A C 1 ATOM 5566 O O . ARG A 1 694 ? -14.554 63.396 4.000 1.00 28.03 ? 747 ARG A O 1 ATOM 5567 C CB . ARG A 1 694 ? -15.816 65.338 5.887 1.00 26.06 ? 747 ARG A CB 1 ATOM 5568 C CG . ARG A 1 694 ? -17.233 65.353 5.379 1.00 26.48 ? 747 ARG A CG 1 ATOM 5569 C CD . ARG A 1 694 ? -18.240 65.524 6.465 1.00 27.39 ? 747 ARG A CD 1 ATOM 5570 N NE . ARG A 1 694 ? -19.582 65.152 6.029 1.00 29.18 ? 747 ARG A NE 1 ATOM 5571 C CZ . ARG A 1 694 ? -20.529 66.020 5.732 1.00 28.47 ? 747 ARG A CZ 1 ATOM 5572 N NH1 . ARG A 1 694 ? -20.281 67.320 5.801 1.00 29.14 ? 747 ARG A NH1 1 ATOM 5573 N NH2 . ARG A 1 694 ? -21.721 65.592 5.351 1.00 31.11 ? 747 ARG A NH2 1 ATOM 5574 N N . VAL A 1 695 ? -16.213 62.134 4.857 1.00 24.78 ? 748 VAL A N 1 ATOM 5575 C CA . VAL A 1 695 ? -16.620 61.592 3.571 1.00 24.70 ? 748 VAL A CA 1 ATOM 5576 C C . VAL A 1 695 ? -18.117 61.766 3.322 1.00 23.97 ? 748 VAL A C 1 ATOM 5577 O O . VAL A 1 695 ? -18.505 62.596 2.499 1.00 24.69 ? 748 VAL A O 1 ATOM 5578 C CB . VAL A 1 695 ? -16.169 60.130 3.383 1.00 26.81 ? 748 VAL A CB 1 ATOM 5579 C CG1 . VAL A 1 695 ? -15.384 59.653 4.585 1.00 27.51 ? 748 VAL A CG1 1 ATOM 5580 C CG2 . VAL A 1 695 ? -17.346 59.230 3.080 1.00 27.52 ? 748 VAL A CG2 1 ATOM 5581 N N . TRP A 1 696 ? -18.961 61.014 4.019 1.00 21.02 ? 749 TRP A N 1 ATOM 5582 C CA . TRP A 1 696 ? -20.394 61.238 3.897 1.00 24.01 ? 749 TRP A CA 1 ATOM 5583 C C . TRP A 1 696 ? -20.900 62.238 4.931 1.00 23.72 ? 749 TRP A C 1 ATOM 5584 O O . TRP A 1 696 ? -22.039 62.700 4.839 1.00 26.62 ? 749 TRP A O 1 ATOM 5585 C CB . TRP A 1 696 ? -21.173 59.919 3.960 1.00 23.19 ? 749 TRP A CB 1 ATOM 5586 C CG . TRP A 1 696 ? -20.721 58.928 2.933 1.00 22.69 ? 749 TRP A CG 1 ATOM 5587 C CD1 . TRP A 1 696 ? -19.975 57.823 3.152 1.00 23.28 ? 749 TRP A CD1 1 ATOM 5588 C CD2 . TRP A 1 696 ? -20.979 58.962 1.522 1.00 23.84 ? 749 TRP A CD2 1 ATOM 5589 N NE1 . TRP A 1 696 ? -19.739 57.161 1.971 1.00 23.64 ? 749 TRP A NE1 1 ATOM 5590 C CE2 . TRP A 1 696 ? -20.344 57.845 0.951 1.00 23.35 ? 749 TRP A CE2 1 ATOM 5591 C CE3 . TRP A 1 696 ? -21.652 59.850 0.676 1.00 24.03 ? 749 TRP A CE3 1 ATOM 5592 C CZ2 . TRP A 1 696 ? -20.382 57.581 -0.416 1.00 24.16 ? 749 TRP A CZ2 1 ATOM 5593 C CZ3 . TRP A 1 696 ? -21.683 59.589 -0.677 1.00 25.02 ? 749 TRP A CZ3 1 ATOM 5594 C CH2 . TRP A 1 696 ? -21.059 58.462 -1.209 1.00 24.60 ? 749 TRP A CH2 1 ATOM 5595 O OXT . TRP A 1 696 ? -20.189 62.623 5.856 1.00 20.23 ? 749 TRP A OXT 1 HETATM 5596 C C1 . NAG B 2 . ? -32.189 15.880 33.376 1.00 40.20 ? 752 NAG A C1 1 HETATM 5597 C C2 . NAG B 2 . ? -33.603 15.854 33.946 1.00 41.99 ? 752 NAG A C2 1 HETATM 5598 C C3 . NAG B 2 . ? -33.739 14.554 34.721 1.00 43.95 ? 752 NAG A C3 1 HETATM 5599 C C4 . NAG B 2 . ? -33.619 13.425 33.710 1.00 45.86 ? 752 NAG A C4 1 HETATM 5600 C C5 . NAG B 2 . ? -32.300 13.538 32.941 1.00 45.48 ? 752 NAG A C5 1 HETATM 5601 C C6 . NAG B 2 . ? -32.277 12.530 31.796 1.00 47.19 ? 752 NAG A C6 1 HETATM 5602 C C7 . NAG B 2 . ? -34.790 17.921 34.535 1.00 44.17 ? 752 NAG A C7 1 HETATM 5603 C C8 . NAG B 2 . ? -34.927 19.027 35.543 1.00 45.24 ? 752 NAG A C8 1 HETATM 5604 N N2 . NAG B 2 . ? -33.867 16.996 34.796 1.00 43.20 ? 752 NAG A N2 1 HETATM 5605 O O3 . NAG B 2 . ? -34.975 14.487 35.390 1.00 43.17 ? 752 NAG A O3 1 HETATM 5606 O O4 . NAG B 2 . ? -33.715 12.178 34.368 1.00 46.92 ? 752 NAG A O4 1 HETATM 5607 O O5 . NAG B 2 . ? -32.103 14.842 32.414 1.00 42.97 ? 752 NAG A O5 1 HETATM 5608 O O6 . NAG B 2 . ? -31.562 11.380 32.203 1.00 49.15 ? 752 NAG A O6 1 HETATM 5609 O O7 . NAG B 2 . ? -35.503 17.905 33.537 1.00 45.44 ? 752 NAG A O7 1 HETATM 5610 C C1 . NAG C 2 . ? -14.368 10.933 -5.211 1.00 41.93 ? 753 NAG A C1 1 HETATM 5611 C C2 . NAG C 2 . ? -15.519 9.972 -5.497 1.00 41.98 ? 753 NAG A C2 1 HETATM 5612 C C3 . NAG C 2 . ? -15.378 8.686 -4.705 1.00 43.10 ? 753 NAG A C3 1 HETATM 5613 C C4 . NAG C 2 . ? -13.989 8.127 -4.931 1.00 43.87 ? 753 NAG A C4 1 HETATM 5614 C C5 . NAG C 2 . ? -12.962 9.190 -4.561 1.00 44.26 ? 753 NAG A C5 1 HETATM 5615 C C6 . NAG C 2 . ? -11.545 8.646 -4.649 1.00 43.39 ? 753 NAG A C6 1 HETATM 5616 C C7 . NAG C 2 . ? -17.273 11.498 -6.033 1.00 42.82 ? 753 NAG A C7 1 HETATM 5617 C C8 . NAG C 2 . ? -18.403 12.351 -5.527 1.00 41.78 ? 753 NAG A C8 1 HETATM 5618 N N2 . NAG C 2 . ? -16.784 10.597 -5.190 1.00 40.18 ? 753 NAG A N2 1 HETATM 5619 O O3 . NAG C 2 . ? -16.345 7.752 -5.123 1.00 43.30 ? 753 NAG A O3 1 HETATM 5620 O O4 . NAG C 2 . ? -13.837 6.983 -4.131 1.00 46.11 ? 753 NAG A O4 1 HETATM 5621 O O5 . NAG C 2 . ? -13.128 10.297 -5.427 1.00 43.48 ? 753 NAG A O5 1 HETATM 5622 O O6 . NAG C 2 . ? -11.446 7.529 -3.794 1.00 44.73 ? 753 NAG A O6 1 HETATM 5623 O O7 . NAG C 2 . ? -16.826 11.648 -7.177 1.00 42.52 ? 753 NAG A O7 1 HETATM 5624 C C1 . NAG D 2 . ? -0.833 58.777 11.862 1.00 42.58 ? 754 NAG A C1 1 HETATM 5625 C C2 . NAG D 2 . ? -0.606 57.470 11.119 1.00 43.79 ? 754 NAG A C2 1 HETATM 5626 C C3 . NAG D 2 . ? 0.609 57.597 10.218 1.00 45.50 ? 754 NAG A C3 1 HETATM 5627 C C4 . NAG D 2 . ? 0.430 58.810 9.317 1.00 46.07 ? 754 NAG A C4 1 HETATM 5628 C C5 . NAG D 2 . ? 0.109 60.041 10.162 1.00 45.76 ? 754 NAG A C5 1 HETATM 5629 C C6 . NAG D 2 . ? -0.071 61.283 9.302 1.00 45.74 ? 754 NAG A C6 1 HETATM 5630 C C7 . NAG D 2 . ? -0.799 55.150 11.713 1.00 41.74 ? 754 NAG A C7 1 HETATM 5631 C C8 . NAG D 2 . ? -0.281 54.049 12.585 1.00 42.79 ? 754 NAG A C8 1 HETATM 5632 N N2 . NAG D 2 . ? -0.426 56.374 12.047 1.00 42.78 ? 754 NAG A N2 1 HETATM 5633 O O3 . NAG D 2 . ? 0.753 56.425 9.446 1.00 47.34 ? 754 NAG A O3 1 HETATM 5634 O O4 . NAG D 2 . ? 1.624 59.014 8.599 1.00 46.62 ? 754 NAG A O4 1 HETATM 5635 O O5 . NAG D 2 . ? -1.057 59.806 10.923 1.00 43.50 ? 754 NAG A O5 1 HETATM 5636 O O6 . NAG D 2 . ? -0.808 60.924 8.160 1.00 47.59 ? 754 NAG A O6 1 HETATM 5637 O O7 . NAG D 2 . ? -1.522 54.913 10.745 1.00 41.50 ? 754 NAG A O7 1 HETATM 5638 ZN ZN . ZN E 3 . ? -21.523 48.931 11.251 1.00 21.99 ? 800 ZN A ZN 1 HETATM 5639 C C . ACT F 4 . ? -7.224 25.750 9.447 1.00 32.31 ? 801 ACT A C 1 HETATM 5640 O O . ACT F 4 . ? -7.262 25.623 10.693 1.00 24.49 ? 801 ACT A O 1 HETATM 5641 O OXT . ACT F 4 . ? -7.851 24.918 8.739 1.00 32.44 ? 801 ACT A OXT 1 HETATM 5642 C CH3 . ACT F 4 . ? -6.467 26.874 8.823 1.00 35.21 ? 801 ACT A CH3 1 HETATM 5643 S S10 . STS G 5 . ? -22.268 47.065 12.157 1.00 25.02 ? 900 STS A S10 1 HETATM 5644 C C2 . STS G 5 . ? -23.670 47.519 13.215 1.00 24.13 ? 900 STS A C2 1 HETATM 5645 C C1 . STS G 5 . ? -23.326 48.465 14.360 1.00 24.91 ? 900 STS A C1 1 HETATM 5646 C C11 . STS G 5 . ? -22.567 47.749 15.413 1.00 25.53 ? 900 STS A C11 1 HETATM 5647 N N13 . STS G 5 . ? -22.885 46.532 15.896 1.00 27.56 ? 900 STS A N13 1 HETATM 5648 C C15 . STS G 5 . ? -22.002 46.181 16.831 1.00 28.13 ? 900 STS A C15 1 HETATM 5649 C C14 . STS G 5 . ? -21.079 47.309 16.923 1.00 27.57 ? 900 STS A C14 1 HETATM 5650 N N12 . STS G 5 . ? -21.474 48.214 16.029 1.00 25.37 ? 900 STS A N12 1 HETATM 5651 C C16 . STS G 5 . ? -20.050 47.219 17.833 1.00 28.15 ? 900 STS A C16 1 HETATM 5652 C C19 . STS G 5 . ? -19.928 46.078 18.618 1.00 31.77 ? 900 STS A C19 1 HETATM 5653 N N18 . STS G 5 . ? -20.793 45.056 18.517 1.00 33.88 ? 900 STS A N18 1 HETATM 5654 C C17 . STS G 5 . ? -21.827 45.082 17.658 1.00 30.75 ? 900 STS A C17 1 HETATM 5655 C C3 . STS G 5 . ? -24.630 48.981 14.958 1.00 25.57 ? 900 STS A C3 1 HETATM 5656 C C4 . STS G 5 . ? -24.400 50.205 15.806 1.00 26.69 ? 900 STS A C4 1 HETATM 5657 C C5 . STS G 5 . ? -24.602 50.158 17.182 1.00 27.39 ? 900 STS A C5 1 HETATM 5658 C C6 . STS G 5 . ? -24.398 51.295 17.959 1.00 29.07 ? 900 STS A C6 1 HETATM 5659 C C7 . STS G 5 . ? -23.977 52.477 17.359 1.00 28.76 ? 900 STS A C7 1 HETATM 5660 C C8 . STS G 5 . ? -23.781 52.526 15.983 1.00 28.14 ? 900 STS A C8 1 HETATM 5661 C C9 . STS G 5 . ? -23.992 51.388 15.208 1.00 28.09 ? 900 STS A C9 1 HETATM 5662 O O . HOH H 6 . ? -14.857 48.416 9.197 1.00 19.51 ? 901 HOH A O 1 HETATM 5663 O O . HOH H 6 . ? -13.104 48.308 6.680 1.00 26.77 ? 902 HOH A O 1 HETATM 5664 O O . HOH H 6 . ? -17.962 47.783 5.693 1.00 21.63 ? 903 HOH A O 1 HETATM 5665 O O . HOH H 6 . ? -20.671 47.292 3.735 1.00 35.42 ? 904 HOH A O 1 HETATM 5666 O O . HOH H 6 . ? -24.477 43.301 8.372 1.00 36.33 ? 905 HOH A O 1 HETATM 5667 O O . HOH H 6 . ? -15.978 51.950 14.290 1.00 22.70 ? 906 HOH A O 1 HETATM 5668 O O . HOH H 6 . ? -15.309 55.513 14.906 1.00 17.53 ? 907 HOH A O 1 HETATM 5669 O O . HOH H 6 . ? -23.008 55.326 19.322 1.00 45.99 ? 908 HOH A O 1 HETATM 5670 O O . HOH H 6 . ? -26.063 56.068 18.887 1.00 22.51 ? 909 HOH A O 1 HETATM 5671 O O . HOH H 6 . ? -22.756 62.992 7.542 1.00 23.38 ? 910 HOH A O 1 HETATM 5672 O O . HOH H 6 . ? -24.365 62.066 4.485 1.00 27.69 ? 911 HOH A O 1 HETATM 5673 O O . HOH H 6 . ? -23.407 68.638 4.882 1.00 39.35 ? 912 HOH A O 1 HETATM 5674 O O . HOH H 6 . ? -18.119 61.286 7.070 1.00 25.17 ? 913 HOH A O 1 HETATM 5675 O O . HOH H 6 . ? -18.612 59.142 6.380 1.00 21.22 ? 914 HOH A O 1 HETATM 5676 O O . HOH H 6 . ? -11.614 63.021 4.641 1.00 25.97 ? 915 HOH A O 1 HETATM 5677 O O . HOH H 6 . ? -9.358 64.450 13.436 1.00 32.96 ? 916 HOH A O 1 HETATM 5678 O O . HOH H 6 . ? -4.029 57.645 21.052 1.00 25.45 ? 917 HOH A O 1 HETATM 5679 O O . HOH H 6 . ? -26.559 52.863 31.765 1.00 23.57 ? 918 HOH A O 1 HETATM 5680 O O . HOH H 6 . ? -24.376 53.289 35.555 1.00 36.31 ? 919 HOH A O 1 HETATM 5681 O O . HOH H 6 . ? -32.873 55.283 34.864 1.00 28.31 ? 920 HOH A O 1 HETATM 5682 O O . HOH H 6 . ? -39.391 51.131 26.583 1.00 41.45 ? 921 HOH A O 1 HETATM 5683 O O . HOH H 6 . ? -41.315 53.016 22.394 1.00 26.06 ? 922 HOH A O 1 HETATM 5684 O O . HOH H 6 . ? -39.942 49.015 21.904 1.00 36.34 ? 923 HOH A O 1 HETATM 5685 O O . HOH H 6 . ? -47.680 49.286 20.351 1.00 28.84 ? 924 HOH A O 1 HETATM 5686 O O . HOH H 6 . ? -45.957 43.562 18.960 1.00 52.64 ? 925 HOH A O 1 HETATM 5687 O O . HOH H 6 . ? -46.810 40.820 19.209 1.00 45.18 ? 926 HOH A O 1 HETATM 5688 O O . HOH H 6 . ? -42.233 21.704 13.345 1.00 34.07 ? 927 HOH A O 1 HETATM 5689 O O . HOH H 6 . ? -40.763 30.740 9.065 1.00 35.67 ? 928 HOH A O 1 HETATM 5690 O O . HOH H 6 . ? -41.749 27.710 6.292 1.00 32.78 ? 929 HOH A O 1 HETATM 5691 O O . HOH H 6 . ? -37.784 35.800 7.456 1.00 28.95 ? 930 HOH A O 1 HETATM 5692 O O . HOH H 6 . ? -21.882 27.994 -8.624 1.00 45.02 ? 931 HOH A O 1 HETATM 5693 O O . HOH H 6 . ? -23.892 29.252 -10.195 1.00 32.57 ? 932 HOH A O 1 HETATM 5694 O O . HOH H 6 . ? -0.590 26.995 -7.656 1.00 26.92 ? 933 HOH A O 1 HETATM 5695 O O . HOH H 6 . ? -17.321 8.543 6.909 1.00 44.06 ? 934 HOH A O 1 HETATM 5696 O O . HOH H 6 . ? -21.356 9.657 7.375 1.00 43.90 ? 935 HOH A O 1 HETATM 5697 O O . HOH H 6 . ? -23.060 10.521 19.216 1.00 37.38 ? 936 HOH A O 1 HETATM 5698 O O . HOH H 6 . ? -8.365 5.530 30.417 1.00 41.13 ? 937 HOH A O 1 HETATM 5699 O O . HOH H 6 . ? -18.086 14.647 34.269 1.00 30.34 ? 938 HOH A O 1 HETATM 5700 O O . HOH H 6 . ? -21.484 20.236 31.818 1.00 27.18 ? 939 HOH A O 1 HETATM 5701 O O . HOH H 6 . ? -24.394 23.261 27.511 1.00 33.59 ? 940 HOH A O 1 HETATM 5702 O O . HOH H 6 . ? -19.694 23.307 22.555 1.00 24.27 ? 941 HOH A O 1 HETATM 5703 O O . HOH H 6 . ? -15.939 23.630 23.005 1.00 27.38 ? 942 HOH A O 1 HETATM 5704 O O . HOH H 6 . ? -12.603 25.970 21.663 1.00 29.69 ? 943 HOH A O 1 HETATM 5705 O O . HOH H 6 . ? -1.075 3.562 16.886 1.00 31.58 ? 944 HOH A O 1 HETATM 5706 O O . HOH H 6 . ? -5.291 5.956 30.544 1.00 37.78 ? 945 HOH A O 1 HETATM 5707 O O . HOH H 6 . ? -9.883 11.704 32.446 1.00 39.40 ? 946 HOH A O 1 HETATM 5708 O O . HOH H 6 . ? -7.008 14.114 31.948 1.00 31.33 ? 947 HOH A O 1 HETATM 5709 O O . HOH H 6 . ? -19.343 17.146 37.427 1.00 45.04 ? 948 HOH A O 1 HETATM 5710 O O . HOH H 6 . ? -21.475 14.739 27.442 1.00 22.07 ? 949 HOH A O 1 HETATM 5711 O O . HOH H 6 . ? -23.135 16.052 25.966 1.00 23.04 ? 950 HOH A O 1 HETATM 5712 O O . HOH H 6 . ? -25.569 15.129 25.252 1.00 19.80 ? 951 HOH A O 1 HETATM 5713 O O . HOH H 6 . ? -37.181 14.070 24.511 1.00 27.11 ? 952 HOH A O 1 HETATM 5714 O O . HOH H 6 . ? -32.048 8.909 24.587 1.00 36.68 ? 953 HOH A O 1 HETATM 5715 O O . HOH H 6 . ? 5.480 24.497 18.455 1.00 56.70 ? 954 HOH A O 1 HETATM 5716 O O . HOH H 6 . ? -5.764 37.151 23.823 1.00 18.00 ? 955 HOH A O 1 HETATM 5717 O O . HOH H 6 . ? -1.689 35.463 24.944 1.00 22.06 ? 956 HOH A O 1 HETATM 5718 O O . HOH H 6 . ? -2.367 38.692 25.493 1.00 21.46 ? 957 HOH A O 1 HETATM 5719 O O . HOH H 6 . ? -3.240 38.000 31.659 1.00 44.48 ? 958 HOH A O 1 HETATM 5720 O O . HOH H 6 . ? -8.192 37.462 33.353 1.00 24.91 ? 959 HOH A O 1 HETATM 5721 O O . HOH H 6 . ? -8.659 39.784 32.174 1.00 17.42 ? 960 HOH A O 1 HETATM 5722 O O . HOH H 6 . ? -13.260 46.562 35.046 1.00 35.21 ? 961 HOH A O 1 HETATM 5723 O O . HOH H 6 . ? -20.525 47.213 25.757 1.00 25.36 ? 962 HOH A O 1 HETATM 5724 O O . HOH H 6 . ? -33.102 45.912 28.376 1.00 14.13 ? 963 HOH A O 1 HETATM 5725 O O . HOH H 6 . ? -32.725 44.072 26.342 1.00 18.94 ? 964 HOH A O 1 HETATM 5726 O O . HOH H 6 . ? -35.098 42.895 25.912 1.00 19.83 ? 965 HOH A O 1 HETATM 5727 O O . HOH H 6 . ? -34.603 42.132 31.024 1.00 12.35 ? 966 HOH A O 1 HETATM 5728 O O . HOH H 6 . ? -37.247 45.618 22.182 1.00 20.76 ? 967 HOH A O 1 HETATM 5729 O O . HOH H 6 . ? -16.057 42.216 13.718 1.00 25.01 ? 968 HOH A O 1 HETATM 5730 O O . HOH H 6 . ? -18.122 38.565 38.007 1.00 25.80 ? 969 HOH A O 1 HETATM 5731 O O . HOH H 6 . ? -24.791 40.118 -4.462 1.00 36.22 ? 970 HOH A O 1 HETATM 5732 O O . HOH H 6 . ? -13.654 42.496 -0.294 1.00 33.78 ? 971 HOH A O 1 HETATM 5733 O O . HOH H 6 . ? -11.901 42.725 4.045 1.00 39.69 ? 972 HOH A O 1 HETATM 5734 O O . HOH H 6 . ? -14.946 44.125 6.606 1.00 37.16 ? 973 HOH A O 1 HETATM 5735 O O . HOH H 6 . ? -16.367 42.545 4.678 1.00 56.30 ? 974 HOH A O 1 HETATM 5736 O O . HOH H 6 . ? -5.994 34.775 8.481 1.00 25.37 ? 975 HOH A O 1 HETATM 5737 O O . HOH H 6 . ? -7.949 35.053 10.872 1.00 26.22 ? 976 HOH A O 1 HETATM 5738 O O . HOH H 6 . ? -9.655 32.645 13.171 1.00 46.31 ? 977 HOH A O 1 HETATM 5739 O O . HOH H 6 . ? -10.584 31.155 18.451 1.00 31.60 ? 978 HOH A O 1 HETATM 5740 O O . HOH H 6 . ? -14.074 21.193 5.770 1.00 18.72 ? 979 HOH A O 1 HETATM 5741 O O . HOH H 6 . ? -15.777 26.790 10.004 1.00 22.42 ? 980 HOH A O 1 HETATM 5742 O O . HOH H 6 . ? -21.968 27.259 4.693 1.00 34.94 ? 981 HOH A O 1 HETATM 5743 O O . HOH H 6 . ? -19.060 31.371 4.608 1.00 32.04 ? 982 HOH A O 1 HETATM 5744 O O . HOH H 6 . ? -22.729 26.633 2.010 1.00 38.61 ? 983 HOH A O 1 HETATM 5745 O O . HOH H 6 . ? -21.986 27.458 -12.761 1.00 43.48 ? 984 HOH A O 1 HETATM 5746 O O . HOH H 6 . ? -28.511 27.444 6.772 1.00 34.12 ? 985 HOH A O 1 HETATM 5747 O O . HOH H 6 . ? -20.523 35.700 -1.744 1.00 26.73 ? 986 HOH A O 1 HETATM 5748 O O . HOH H 6 . ? -19.646 35.761 0.989 1.00 45.37 ? 987 HOH A O 1 HETATM 5749 O O . HOH H 6 . ? -19.580 36.204 -4.864 1.00 26.05 ? 988 HOH A O 1 HETATM 5750 O O . HOH H 6 . ? -14.348 37.552 -12.297 1.00 16.39 ? 989 HOH A O 1 HETATM 5751 O O . HOH H 6 . ? -16.193 31.736 -15.388 1.00 23.04 ? 990 HOH A O 1 HETATM 5752 O O . HOH H 6 . ? -17.039 12.990 2.051 1.00 33.45 ? 991 HOH A O 1 HETATM 5753 O O . HOH H 6 . ? -26.171 24.851 14.816 1.00 25.42 ? 992 HOH A O 1 HETATM 5754 O O . HOH H 6 . ? -24.936 27.654 16.862 1.00 29.05 ? 993 HOH A O 1 HETATM 5755 O O . HOH H 6 . ? -19.290 23.527 12.151 1.00 35.43 ? 994 HOH A O 1 HETATM 5756 O O . HOH H 6 . ? -16.888 26.962 22.290 1.00 42.65 ? 995 HOH A O 1 HETATM 5757 O O . HOH H 6 . ? -17.483 40.344 23.569 1.00 40.47 ? 996 HOH A O 1 HETATM 5758 O O . HOH H 6 . ? -18.188 39.510 27.114 1.00 22.92 ? 997 HOH A O 1 HETATM 5759 O O . HOH H 6 . ? -15.479 33.923 27.493 1.00 14.95 ? 998 HOH A O 1 HETATM 5760 O O . HOH H 6 . ? -17.503 33.693 29.722 1.00 24.58 ? 999 HOH A O 1 HETATM 5761 O O . HOH H 6 . ? -7.528 25.532 27.760 1.00 21.00 ? 1000 HOH A O 1 HETATM 5762 O O . HOH H 6 . ? -7.541 25.349 31.953 1.00 36.22 ? 1001 HOH A O 1 HETATM 5763 O O . HOH H 6 . ? -24.017 26.902 24.105 1.00 33.96 ? 1002 HOH A O 1 HETATM 5764 O O . HOH H 6 . ? -35.450 30.554 12.556 1.00 24.15 ? 1003 HOH A O 1 HETATM 5765 O O . HOH H 6 . ? -34.345 35.897 17.609 1.00 21.12 ? 1004 HOH A O 1 HETATM 5766 O O . HOH H 6 . ? -35.550 31.515 8.761 1.00 38.00 ? 1005 HOH A O 1 HETATM 5767 O O . HOH H 6 . ? -32.203 25.681 12.617 1.00 28.73 ? 1006 HOH A O 1 HETATM 5768 O O . HOH H 6 . ? -27.817 40.610 20.719 1.00 20.75 ? 1007 HOH A O 1 HETATM 5769 O O . HOH H 6 . ? -41.791 48.129 7.155 1.00 33.67 ? 1008 HOH A O 1 HETATM 5770 O O . HOH H 6 . ? -34.353 28.495 33.269 1.00 22.58 ? 1009 HOH A O 1 HETATM 5771 O O . HOH H 6 . ? -41.280 30.004 29.833 1.00 36.21 ? 1010 HOH A O 1 HETATM 5772 O O . HOH H 6 . ? -40.982 32.358 33.015 1.00 26.42 ? 1011 HOH A O 1 HETATM 5773 O O . HOH H 6 . ? -46.670 28.981 32.081 1.00 50.85 ? 1012 HOH A O 1 HETATM 5774 O O . HOH H 6 . ? -46.634 22.187 25.179 1.00 50.47 ? 1013 HOH A O 1 HETATM 5775 O O . HOH H 6 . ? -44.762 24.369 26.044 1.00 43.65 ? 1014 HOH A O 1 HETATM 5776 O O . HOH H 6 . ? -42.788 22.412 25.911 1.00 32.05 ? 1015 HOH A O 1 HETATM 5777 O O . HOH H 6 . ? -45.621 17.509 20.428 1.00 34.10 ? 1016 HOH A O 1 HETATM 5778 O O . HOH H 6 . ? -46.346 31.952 20.959 1.00 27.75 ? 1017 HOH A O 1 HETATM 5779 O O . HOH H 6 . ? -43.765 38.161 7.632 1.00 33.81 ? 1018 HOH A O 1 HETATM 5780 O O . HOH H 6 . ? -40.265 46.100 8.527 1.00 26.35 ? 1019 HOH A O 1 HETATM 5781 O O . HOH H 6 . ? -41.732 44.205 9.514 1.00 22.59 ? 1020 HOH A O 1 HETATM 5782 O O . HOH H 6 . ? -17.613 49.020 18.907 1.00 19.76 ? 1021 HOH A O 1 HETATM 5783 O O . HOH H 6 . ? -11.926 46.946 19.154 1.00 31.15 ? 1022 HOH A O 1 HETATM 5784 O O . HOH H 6 . ? -10.887 46.910 16.252 1.00 23.38 ? 1023 HOH A O 1 HETATM 5785 O O . HOH H 6 . ? -8.143 47.626 15.255 1.00 18.45 ? 1024 HOH A O 1 HETATM 5786 O O . HOH H 6 . ? -3.570 46.021 14.934 1.00 30.94 ? 1025 HOH A O 1 HETATM 5787 O O . HOH H 6 . ? -4.120 44.681 12.195 1.00 31.51 ? 1026 HOH A O 1 HETATM 5788 O O . HOH H 6 . ? -3.581 51.530 10.065 1.00 24.59 ? 1027 HOH A O 1 HETATM 5789 O O . HOH H 6 . ? -10.211 54.185 9.583 1.00 27.57 ? 1028 HOH A O 1 HETATM 5790 O O . HOH H 6 . ? -17.010 50.845 25.052 1.00 19.82 ? 1029 HOH A O 1 HETATM 5791 O O . HOH H 6 . ? -14.754 51.369 24.513 1.00 22.37 ? 1030 HOH A O 1 HETATM 5792 O O . HOH H 6 . ? -19.624 63.978 9.915 1.00 40.27 ? 1031 HOH A O 1 HETATM 5793 O O . HOH H 6 . ? -17.093 63.145 9.505 1.00 33.53 ? 1032 HOH A O 1 HETATM 5794 O O . HOH H 6 . ? -6.621 62.660 10.701 1.00 33.14 ? 1033 HOH A O 1 HETATM 5795 O O . HOH H 6 . ? -7.005 62.126 16.739 1.00 33.18 ? 1034 HOH A O 1 HETATM 5796 O O . HOH H 6 . ? 0.139 59.276 17.176 1.00 44.09 ? 1035 HOH A O 1 HETATM 5797 O O . HOH H 6 . ? -8.660 61.755 -6.077 1.00 25.20 ? 1036 HOH A O 1 HETATM 5798 O O . HOH H 6 . ? -14.587 53.378 -11.010 1.00 28.24 ? 1037 HOH A O 1 HETATM 5799 O O . HOH H 6 . ? -14.736 57.889 -15.027 1.00 25.53 ? 1038 HOH A O 1 HETATM 5800 O O . HOH H 6 . ? -15.456 60.502 -15.909 1.00 29.98 ? 1039 HOH A O 1 HETATM 5801 O O . HOH H 6 . ? -13.126 60.620 -14.106 1.00 34.34 ? 1040 HOH A O 1 HETATM 5802 O O . HOH H 6 . ? -12.516 51.993 -7.148 1.00 20.99 ? 1041 HOH A O 1 HETATM 5803 O O . HOH H 6 . ? -19.596 50.540 -7.522 1.00 20.10 ? 1042 HOH A O 1 HETATM 5804 O O . HOH H 6 . ? -15.388 47.874 5.007 1.00 37.40 ? 1043 HOH A O 1 HETATM 5805 O O . HOH H 6 . ? -28.548 36.236 3.315 1.00 48.95 ? 1044 HOH A O 1 HETATM 5806 O O . HOH H 6 . ? -2.490 29.715 -16.118 1.00 48.47 ? 1045 HOH A O 1 HETATM 5807 O O . HOH H 6 . ? -15.073 12.126 -8.997 1.00 32.25 ? 1046 HOH A O 1 HETATM 5808 O O . HOH H 6 . ? -10.589 10.938 -6.320 1.00 26.53 ? 1047 HOH A O 1 HETATM 5809 O O . HOH H 6 . ? -8.716 6.296 -2.387 1.00 35.27 ? 1048 HOH A O 1 HETATM 5810 O O . HOH H 6 . ? 2.231 14.798 -0.888 1.00 31.87 ? 1049 HOH A O 1 HETATM 5811 O O . HOH H 6 . ? -7.947 36.230 -0.125 1.00 28.35 ? 1050 HOH A O 1 HETATM 5812 O O . HOH H 6 . ? 3.282 29.998 5.389 1.00 26.16 ? 1051 HOH A O 1 HETATM 5813 O O . HOH H 6 . ? 2.657 31.182 2.593 1.00 32.40 ? 1052 HOH A O 1 HETATM 5814 O O . HOH H 6 . ? 2.032 35.581 9.976 1.00 37.01 ? 1053 HOH A O 1 HETATM 5815 O O . HOH H 6 . ? -1.740 42.963 11.489 1.00 31.73 ? 1054 HOH A O 1 HETATM 5816 O O . HOH H 6 . ? -4.638 39.978 11.254 1.00 19.35 ? 1055 HOH A O 1 HETATM 5817 O O . HOH H 6 . ? -1.477 44.541 8.791 1.00 27.32 ? 1056 HOH A O 1 HETATM 5818 O O . HOH H 6 . ? -1.976 39.683 2.744 1.00 45.87 ? 1057 HOH A O 1 HETATM 5819 O O . HOH H 6 . ? 0.487 41.845 4.008 1.00 43.23 ? 1058 HOH A O 1 HETATM 5820 O O . HOH H 6 . ? -24.874 61.699 1.783 1.00 23.74 ? 1059 HOH A O 1 HETATM 5821 O O . HOH H 6 . ? -15.222 51.853 -7.997 1.00 36.20 ? 1060 HOH A O 1 HETATM 5822 O O . HOH H 6 . ? -23.323 51.268 -13.654 1.00 33.06 ? 1061 HOH A O 1 HETATM 5823 O O . HOH H 6 . ? -24.963 49.838 -11.887 1.00 31.53 ? 1062 HOH A O 1 HETATM 5824 O O . HOH H 6 . ? -27.414 51.431 -8.935 1.00 29.75 ? 1063 HOH A O 1 HETATM 5825 O O . HOH H 6 . ? -36.345 60.269 -0.112 1.00 31.71 ? 1064 HOH A O 1 HETATM 5826 O O . HOH H 6 . ? -37.879 59.354 2.408 1.00 33.66 ? 1065 HOH A O 1 HETATM 5827 O O . HOH H 6 . ? -33.676 49.498 27.529 1.00 26.87 ? 1066 HOH A O 1 HETATM 5828 O O . HOH H 6 . ? -31.726 49.281 29.762 1.00 36.03 ? 1067 HOH A O 1 HETATM 5829 O O . HOH H 6 . ? -25.210 42.904 33.282 1.00 27.73 ? 1068 HOH A O 1 HETATM 5830 O O . HOH H 6 . ? -18.886 31.476 28.044 1.00 31.93 ? 1069 HOH A O 1 HETATM 5831 O O . HOH H 6 . ? -15.394 27.716 27.559 1.00 31.07 ? 1070 HOH A O 1 HETATM 5832 O O . HOH H 6 . ? -24.619 30.116 23.706 1.00 25.74 ? 1071 HOH A O 1 HETATM 5833 O O . HOH H 6 . ? -22.475 39.981 27.504 1.00 33.86 ? 1072 HOH A O 1 HETATM 5834 O O . HOH H 6 . ? -23.158 34.448 33.669 1.00 25.54 ? 1073 HOH A O 1 HETATM 5835 O O . HOH H 6 . ? -28.543 40.178 33.150 1.00 20.91 ? 1074 HOH A O 1 HETATM 5836 O O . HOH H 6 . ? -30.975 42.094 34.620 1.00 27.93 ? 1075 HOH A O 1 HETATM 5837 O O . HOH H 6 . ? -29.811 44.552 34.446 1.00 29.23 ? 1076 HOH A O 1 HETATM 5838 O O . HOH H 6 . ? -12.390 29.777 19.915 1.00 34.52 ? 1077 HOH A O 1 HETATM 5839 O O . HOH H 6 . ? -19.057 27.489 25.230 1.00 32.11 ? 1078 HOH A O 1 HETATM 5840 O O . HOH H 6 . ? -17.336 48.575 21.606 1.00 48.74 ? 1079 HOH A O 1 HETATM 5841 O O . HOH H 6 . ? -22.389 41.102 17.714 1.00 29.98 ? 1080 HOH A O 1 HETATM 5842 O O . HOH H 6 . ? -16.272 35.860 26.320 1.00 19.56 ? 1081 HOH A O 1 HETATM 5843 O O . HOH H 6 . ? -17.170 35.851 23.749 1.00 52.04 ? 1082 HOH A O 1 HETATM 5844 O O . HOH H 6 . ? -11.109 39.299 6.022 1.00 26.51 ? 1083 HOH A O 1 HETATM 5845 O O . HOH H 6 . ? -12.199 34.275 6.649 1.00 36.58 ? 1084 HOH A O 1 HETATM 5846 O O . HOH H 6 . ? -29.092 35.561 21.776 1.00 24.13 ? 1085 HOH A O 1 HETATM 5847 O O . HOH H 6 . ? -28.949 35.022 16.827 1.00 41.74 ? 1086 HOH A O 1 HETATM 5848 O O . HOH H 6 . ? -26.038 32.980 15.335 1.00 49.87 ? 1087 HOH A O 1 HETATM 5849 O O . HOH H 6 . ? -28.141 27.984 34.860 1.00 28.22 ? 1088 HOH A O 1 HETATM 5850 O O . HOH H 6 . ? -32.601 27.372 34.705 1.00 39.42 ? 1089 HOH A O 1 HETATM 5851 O O . HOH H 6 . ? -37.791 34.603 35.581 1.00 27.53 ? 1090 HOH A O 1 HETATM 5852 O O . HOH H 6 . ? -37.690 55.364 -1.466 1.00 40.69 ? 1091 HOH A O 1 HETATM 5853 O O . HOH H 6 . ? -11.018 65.017 -2.212 1.00 48.86 ? 1092 HOH A O 1 HETATM 5854 O O . HOH H 6 . ? -6.448 54.253 25.153 1.00 30.75 ? 1093 HOH A O 1 HETATM 5855 O O . HOH H 6 . ? -9.994 56.978 25.403 1.00 44.30 ? 1094 HOH A O 1 HETATM 5856 O O . HOH H 6 . ? 2.980 50.256 22.613 1.00 37.20 ? 1095 HOH A O 1 HETATM 5857 O O . HOH H 6 . ? -4.235 31.363 30.083 1.00 19.80 ? 1096 HOH A O 1 HETATM 5858 O O . HOH H 6 . ? 7.184 8.868 22.547 1.00 40.14 ? 1097 HOH A O 1 HETATM 5859 O O . HOH H 6 . ? -13.806 40.276 17.867 1.00 31.27 ? 1098 HOH A O 1 HETATM 5860 O O . HOH H 6 . ? -12.314 35.245 19.335 1.00 25.37 ? 1099 HOH A O 1 HETATM 5861 O O . HOH H 6 . ? -24.660 37.457 21.937 1.00 39.90 ? 1100 HOH A O 1 HETATM 5862 O O . HOH H 6 . ? -28.903 33.234 0.933 1.00 46.00 ? 1101 HOH A O 1 HETATM 5863 O O . HOH H 6 . ? -29.094 35.484 10.771 1.00 45.09 ? 1102 HOH A O 1 HETATM 5864 O O . HOH H 6 . ? -21.957 43.290 14.367 1.00 37.80 ? 1103 HOH A O 1 HETATM 5865 O O . HOH H 6 . ? -45.430 27.327 4.552 1.00 30.27 ? 1104 HOH A O 1 HETATM 5866 O O . HOH H 6 . ? -48.635 28.453 5.221 1.00 38.77 ? 1105 HOH A O 1 HETATM 5867 O O . HOH H 6 . ? -50.864 29.133 10.030 1.00 28.50 ? 1106 HOH A O 1 HETATM 5868 O O . HOH H 6 . ? -48.445 23.486 16.036 1.00 23.01 ? 1107 HOH A O 1 HETATM 5869 O O . HOH H 6 . ? -51.757 22.622 20.693 1.00 39.69 ? 1108 HOH A O 1 HETATM 5870 O O . HOH H 6 . ? -14.331 55.399 45.411 1.00 32.28 ? 1109 HOH A O 1 HETATM 5871 O O . HOH H 6 . ? -12.234 74.301 25.974 1.00 28.05 ? 1110 HOH A O 1 HETATM 5872 O O . HOH H 6 . ? -7.792 69.731 24.884 1.00 29.72 ? 1111 HOH A O 1 HETATM 5873 O O . HOH H 6 . ? 0.071 37.162 2.958 1.00 31.73 ? 1112 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLY 1 54 54 GLY GLY A . n A 1 2 ILE 2 55 55 ILE ILE A . n A 1 3 CYS 3 56 56 CYS CYS A . n A 1 4 LYS 4 57 57 LYS LYS A . n A 1 5 SER 5 58 58 SER SER A . n A 1 6 SER 6 59 59 SER SER A . n A 1 7 ASP 7 60 60 ASP ASP A . n A 1 8 CYS 8 61 61 CYS CYS A . n A 1 9 ILE 9 62 62 ILE ILE A . n A 1 10 LYS 10 63 63 LYS LYS A . n A 1 11 SER 11 64 64 SER SER A . n A 1 12 ALA 12 65 65 ALA ALA A . n A 1 13 ALA 13 66 66 ALA ALA A . n A 1 14 ARG 14 67 67 ARG ARG A . n A 1 15 LEU 15 68 68 LEU LEU A . n A 1 16 ILE 16 69 69 ILE ILE A . n A 1 17 GLN 17 70 70 GLN GLN A . n A 1 18 ASN 18 71 71 ASN ASN A . n A 1 19 MET 19 72 72 MET MET A . n A 1 20 ASP 20 73 73 ASP ASP A . n A 1 21 ALA 21 74 74 ALA ALA A . n A 1 22 THR 22 75 75 THR THR A . n A 1 23 THR 23 76 76 THR THR A . n A 1 24 GLU 24 77 77 GLU GLU A . n A 1 25 PRO 25 78 78 PRO PRO A . n A 1 26 CYS 26 79 79 CYS CYS A . n A 1 27 THR 27 80 80 THR THR A . n A 1 28 ASP 28 81 81 ASP ASP A . n A 1 29 PHE 29 82 82 PHE PHE A . n A 1 30 PHE 30 83 83 PHE PHE A . n A 1 31 LYS 31 84 84 LYS LYS A . n A 1 32 TYR 32 85 85 TYR TYR A . n A 1 33 ALA 33 86 86 ALA ALA A . n A 1 34 CYS 34 87 87 CYS CYS A . n A 1 35 GLY 35 88 88 GLY GLY A . n A 1 36 GLY 36 89 89 GLY GLY A . n A 1 37 TRP 37 90 90 TRP TRP A . n A 1 38 LEU 38 91 91 LEU LEU A . n A 1 39 LYS 39 92 92 LYS LYS A . n A 1 40 ARG 40 93 93 ARG ARG A . n A 1 41 ASN 41 94 94 ASN ASN A . n A 1 42 VAL 42 95 95 VAL VAL A . n A 1 43 ILE 43 96 96 ILE ILE A . n A 1 44 PRO 44 97 97 PRO PRO A . n A 1 45 GLU 45 98 98 GLU GLU A . n A 1 46 THR 46 99 99 THR THR A . n A 1 47 SER 47 100 100 SER SER A . n A 1 48 SER 48 101 101 SER SER A . n A 1 49 ARG 49 102 102 ARG ARG A . n A 1 50 TYR 50 103 103 TYR TYR A . n A 1 51 GLY 51 104 104 GLY GLY A . n A 1 52 ASN 52 105 105 ASN ASN A . n A 1 53 PHE 53 106 106 PHE PHE A . n A 1 54 ASP 54 107 107 ASP ASP A . n A 1 55 ILE 55 108 108 ILE ILE A . n A 1 56 LEU 56 109 109 LEU LEU A . n A 1 57 ARG 57 110 110 ARG ARG A . n A 1 58 ASP 58 111 111 ASP ASP A . n A 1 59 GLU 59 112 112 GLU GLU A . n A 1 60 LEU 60 113 113 LEU LEU A . n A 1 61 GLU 61 114 114 GLU GLU A . n A 1 62 VAL 62 115 115 VAL VAL A . n A 1 63 VAL 63 116 116 VAL VAL A . n A 1 64 LEU 64 117 117 LEU LEU A . n A 1 65 LYS 65 118 118 LYS LYS A . n A 1 66 ASP 66 119 119 ASP ASP A . n A 1 67 VAL 67 120 120 VAL VAL A . n A 1 68 LEU 68 121 121 LEU LEU A . n A 1 69 GLN 69 122 122 GLN GLN A . n A 1 70 GLU 70 123 123 GLU GLU A . n A 1 71 PRO 71 124 124 PRO PRO A . n A 1 72 LYS 72 125 125 LYS LYS A . n A 1 73 THR 73 126 126 THR THR A . n A 1 74 GLU 74 127 127 GLU GLU A . n A 1 75 ASP 75 128 128 ASP ASP A . n A 1 76 ILE 76 129 129 ILE ILE A . n A 1 77 VAL 77 130 130 VAL VAL A . n A 1 78 ALA 78 131 131 ALA ALA A . n A 1 79 VAL 79 132 132 VAL VAL A . n A 1 80 GLN 80 133 133 GLN GLN A . n A 1 81 LYS 81 134 134 LYS LYS A . n A 1 82 ALA 82 135 135 ALA ALA A . n A 1 83 LYS 83 136 136 LYS LYS A . n A 1 84 ALA 84 137 137 ALA ALA A . n A 1 85 LEU 85 138 138 LEU LEU A . n A 1 86 TYR 86 139 139 TYR TYR A . n A 1 87 ARG 87 140 140 ARG ARG A . n A 1 88 SER 88 141 141 SER SER A . n A 1 89 CYS 89 142 142 CYS CYS A . n A 1 90 ILE 90 143 143 ILE ILE A . n A 1 91 ASN 91 144 144 ASN ASN A . n A 1 92 GLU 92 145 145 GLU GLU A . n A 1 93 SER 93 146 146 SER SER A . n A 1 94 ALA 94 147 147 ALA ALA A . n A 1 95 ILE 95 148 148 ILE ILE A . n A 1 96 ASP 96 149 149 ASP ASP A . n A 1 97 SER 97 150 150 SER SER A . n A 1 98 ARG 98 151 151 ARG ARG A . n A 1 99 GLY 99 152 152 GLY GLY A . n A 1 100 GLY 100 153 153 GLY GLY A . n A 1 101 GLU 101 154 154 GLU GLU A . n A 1 102 PRO 102 155 155 PRO PRO A . n A 1 103 LEU 103 156 156 LEU LEU A . n A 1 104 LEU 104 157 157 LEU LEU A . n A 1 105 LYS 105 158 158 LYS LYS A . n A 1 106 LEU 106 159 159 LEU LEU A . n A 1 107 LEU 107 160 160 LEU LEU A . n A 1 108 PRO 108 161 161 PRO PRO A . n A 1 109 ASP 109 162 162 ASP ASP A . n A 1 110 ILE 110 163 163 ILE ILE A . n A 1 111 TYR 111 164 164 TYR TYR A . n A 1 112 GLY 112 165 165 GLY GLY A . n A 1 113 TRP 113 166 166 TRP TRP A . n A 1 114 PRO 114 167 167 PRO PRO A . n A 1 115 VAL 115 168 168 VAL VAL A . n A 1 116 ALA 116 169 169 ALA ALA A . n A 1 117 THR 117 170 170 THR THR A . n A 1 118 GLU 118 171 171 GLU GLU A . n A 1 119 ASN 119 172 172 ASN ASN A . n A 1 120 TRP 120 173 173 TRP TRP A . n A 1 121 GLU 121 174 174 GLU GLU A . n A 1 122 GLN 122 175 175 GLN GLN A . n A 1 123 LYS 123 176 176 LYS LYS A . n A 1 124 TYR 124 177 177 TYR TYR A . n A 1 125 GLY 125 178 178 GLY GLY A . n A 1 126 ALA 126 179 179 ALA ALA A . n A 1 127 SER 127 180 180 SER SER A . n A 1 128 TRP 128 181 181 TRP TRP A . n A 1 129 THR 129 182 182 THR THR A . n A 1 130 ALA 130 183 183 ALA ALA A . n A 1 131 GLU 131 184 184 GLU GLU A . n A 1 132 LYS 132 185 185 LYS LYS A . n A 1 133 ALA 133 186 186 ALA ALA A . n A 1 134 ILE 134 187 187 ILE ILE A . n A 1 135 ALA 135 188 188 ALA ALA A . n A 1 136 GLN 136 189 189 GLN GLN A . n A 1 137 LEU 137 190 190 LEU LEU A . n A 1 138 ASN 138 191 191 ASN ASN A . n A 1 139 SER 139 192 192 SER SER A . n A 1 140 LYS 140 193 193 LYS LYS A . n A 1 141 TYR 141 194 194 TYR TYR A . n A 1 142 GLY 142 195 195 GLY GLY A . n A 1 143 LYS 143 196 196 LYS LYS A . n A 1 144 LYS 144 197 197 LYS LYS A . n A 1 145 VAL 145 198 198 VAL VAL A . n A 1 146 LEU 146 199 199 LEU LEU A . n A 1 147 ILE 147 200 200 ILE ILE A . n A 1 148 ASN 148 201 201 ASN ASN A . n A 1 149 LEU 149 202 202 LEU LEU A . n A 1 150 PHE 150 203 203 PHE PHE A . n A 1 151 VAL 151 204 204 VAL VAL A . n A 1 152 GLY 152 205 205 GLY GLY A . n A 1 153 THR 153 206 206 THR THR A . n A 1 154 ASP 154 207 207 ASP ASP A . n A 1 155 ASP 155 208 208 ASP ASP A . n A 1 156 LYS 156 209 209 LYS LYS A . n A 1 157 ASN 157 210 210 ASN ASN A . n A 1 158 SER 158 211 211 SER SER A . n A 1 159 VAL 159 212 212 VAL VAL A . n A 1 160 ASN 160 213 213 ASN ASN A . n A 1 161 HIS 161 214 214 HIS HIS A . n A 1 162 VAL 162 215 215 VAL VAL A . n A 1 163 ILE 163 216 216 ILE ILE A . n A 1 164 HIS 164 217 217 HIS HIS A . n A 1 165 ILE 165 218 218 ILE ILE A . n A 1 166 ASP 166 219 219 ASP ASP A . n A 1 167 GLN 167 220 220 GLN GLN A . n A 1 168 PRO 168 221 221 PRO PRO A . n A 1 169 ARG 169 222 222 ARG ARG A . n A 1 170 LEU 170 223 223 LEU LEU A . n A 1 171 GLY 171 224 224 GLY GLY A . n A 1 172 LEU 172 225 225 LEU LEU A . n A 1 173 PRO 173 226 226 PRO PRO A . n A 1 174 SER 174 227 227 SER SER A . n A 1 175 ARG 175 228 228 ARG ARG A . n A 1 176 ASP 176 229 229 ASP ASP A . n A 1 177 TYR 177 230 230 TYR TYR A . n A 1 178 TYR 178 231 231 TYR TYR A . n A 1 179 GLU 179 232 232 GLU GLU A . n A 1 180 CYS 180 233 233 CYS CYS A . n A 1 181 THR 181 234 234 THR THR A . n A 1 182 GLY 182 235 235 GLY GLY A . n A 1 183 ILE 183 236 236 ILE ILE A . n A 1 184 TYR 184 237 237 TYR TYR A . n A 1 185 LYS 185 238 238 LYS LYS A . n A 1 186 GLU 186 239 239 GLU GLU A . n A 1 187 ALA 187 240 240 ALA ALA A . n A 1 188 CYS 188 241 241 CYS CYS A . n A 1 189 THR 189 242 242 THR THR A . n A 1 190 ALA 190 243 243 ALA ALA A . n A 1 191 TYR 191 244 244 TYR TYR A . n A 1 192 VAL 192 245 245 VAL VAL A . n A 1 193 ASP 193 246 246 ASP ASP A . n A 1 194 PHE 194 247 247 PHE PHE A . n A 1 195 MET 195 248 248 MET MET A . n A 1 196 ILE 196 249 249 ILE ILE A . n A 1 197 SER 197 250 250 SER SER A . n A 1 198 VAL 198 251 251 VAL VAL A . n A 1 199 ALA 199 252 252 ALA ALA A . n A 1 200 ARG 200 253 253 ARG ARG A . n A 1 201 LEU 201 254 254 LEU LEU A . n A 1 202 ILE 202 255 255 ILE ILE A . n A 1 203 ARG 203 256 256 ARG ARG A . n A 1 204 GLN 204 257 257 GLN GLN A . n A 1 205 GLU 205 258 258 GLU GLU A . n A 1 206 GLU 206 259 259 GLU GLU A . n A 1 207 ARG 207 260 260 ARG ARG A . n A 1 208 LEU 208 261 261 LEU LEU A . n A 1 209 PRO 209 262 262 PRO PRO A . n A 1 210 ILE 210 263 263 ILE ILE A . n A 1 211 ASP 211 264 264 ASP ASP A . n A 1 212 GLU 212 265 265 GLU GLU A . n A 1 213 ASN 213 266 266 ASN ASN A . n A 1 214 GLN 214 267 267 GLN GLN A . n A 1 215 LEU 215 268 268 LEU LEU A . n A 1 216 ALA 216 269 269 ALA ALA A . n A 1 217 LEU 217 270 270 LEU LEU A . n A 1 218 GLU 218 271 271 GLU GLU A . n A 1 219 MET 219 272 272 MET MET A . n A 1 220 ASN 220 273 273 ASN ASN A . n A 1 221 LYS 221 274 274 LYS LYS A . n A 1 222 VAL 222 275 275 VAL VAL A . n A 1 223 MET 223 276 276 MET MET A . n A 1 224 GLU 224 277 277 GLU GLU A . n A 1 225 LEU 225 278 278 LEU LEU A . n A 1 226 GLU 226 279 279 GLU GLU A . n A 1 227 LYS 227 280 280 LYS LYS A . n A 1 228 GLU 228 281 281 GLU GLU A . n A 1 229 ILE 229 282 282 ILE ILE A . n A 1 230 ALA 230 283 283 ALA ALA A . n A 1 231 ASN 231 284 284 ASN ASN A . n A 1 232 ALA 232 285 285 ALA ALA A . n A 1 233 THR 233 286 286 THR THR A . n A 1 234 ALA 234 287 287 ALA ALA A . n A 1 235 LYS 235 288 288 LYS LYS A . n A 1 236 PRO 236 289 289 PRO PRO A . n A 1 237 GLU 237 290 290 GLU GLU A . n A 1 238 ASP 238 291 291 ASP ASP A . n A 1 239 ARG 239 292 292 ARG ARG A . n A 1 240 ASN 240 293 293 ASN ASN A . n A 1 241 ASP 241 294 294 ASP ASP A . n A 1 242 PRO 242 295 295 PRO PRO A . n A 1 243 MET 243 296 296 MET MET A . n A 1 244 LEU 244 297 297 LEU LEU A . n A 1 245 LEU 245 298 298 LEU LEU A . n A 1 246 TYR 246 299 299 TYR TYR A . n A 1 247 ASN 247 300 300 ASN ASN A . n A 1 248 LYS 248 301 301 LYS LYS A . n A 1 249 MET 249 302 302 MET MET A . n A 1 250 THR 250 303 303 THR THR A . n A 1 251 LEU 251 304 304 LEU LEU A . n A 1 252 ALA 252 305 305 ALA ALA A . n A 1 253 GLN 253 306 306 GLN GLN A . n A 1 254 ILE 254 307 307 ILE ILE A . n A 1 255 GLN 255 308 308 GLN GLN A . n A 1 256 ASN 256 309 309 ASN ASN A . n A 1 257 ASN 257 310 310 ASN ASN A . n A 1 258 PHE 258 311 311 PHE PHE A . n A 1 259 SER 259 312 312 SER SER A . n A 1 260 LEU 260 313 313 LEU LEU A . n A 1 261 GLU 261 314 314 GLU GLU A . n A 1 262 ILE 262 315 315 ILE ILE A . n A 1 263 ASN 263 316 316 ASN ASN A . n A 1 264 GLY 264 317 317 GLY GLY A . n A 1 265 LYS 265 318 318 LYS LYS A . n A 1 266 PRO 266 319 319 PRO PRO A . n A 1 267 PHE 267 320 320 PHE PHE A . n A 1 268 SER 268 321 321 SER SER A . n A 1 269 TRP 269 322 322 TRP TRP A . n A 1 270 LEU 270 323 323 LEU LEU A . n A 1 271 ASN 271 324 324 ASN ASN A . n A 1 272 PHE 272 325 325 PHE PHE A . n A 1 273 THR 273 326 326 THR THR A . n A 1 274 ASN 274 327 327 ASN ASN A . n A 1 275 GLU 275 328 328 GLU GLU A . n A 1 276 ILE 276 329 329 ILE ILE A . n A 1 277 MET 277 330 330 MET MET A . n A 1 278 SER 278 331 331 SER SER A . n A 1 279 THR 279 332 332 THR THR A . n A 1 280 VAL 280 333 333 VAL VAL A . n A 1 281 ASN 281 334 334 ASN ASN A . n A 1 282 ILE 282 335 335 ILE ILE A . n A 1 283 SER 283 336 336 SER SER A . n A 1 284 ILE 284 337 337 ILE ILE A . n A 1 285 THR 285 338 338 THR THR A . n A 1 286 ASN 286 339 339 ASN ASN A . n A 1 287 GLU 287 340 340 GLU GLU A . n A 1 288 GLU 288 341 341 GLU GLU A . n A 1 289 ASP 289 342 342 ASP ASP A . n A 1 290 VAL 290 343 343 VAL VAL A . n A 1 291 VAL 291 344 344 VAL VAL A . n A 1 292 VAL 292 345 345 VAL VAL A . n A 1 293 TYR 293 346 346 TYR TYR A . n A 1 294 ALA 294 347 347 ALA ALA A . n A 1 295 PRO 295 348 348 PRO PRO A . n A 1 296 GLU 296 349 349 GLU GLU A . n A 1 297 TYR 297 350 350 TYR TYR A . n A 1 298 LEU 298 351 351 LEU LEU A . n A 1 299 THR 299 352 352 THR THR A . n A 1 300 LYS 300 353 353 LYS LYS A . n A 1 301 LEU 301 354 354 LEU LEU A . n A 1 302 LYS 302 355 355 LYS LYS A . n A 1 303 PRO 303 356 356 PRO PRO A . n A 1 304 ILE 304 357 357 ILE ILE A . n A 1 305 LEU 305 358 358 LEU LEU A . n A 1 306 THR 306 359 359 THR THR A . n A 1 307 LYS 307 360 360 LYS LYS A . n A 1 308 TYR 308 361 361 TYR TYR A . n A 1 309 SER 309 362 362 SER SER A . n A 1 310 ALA 310 363 363 ALA ALA A . n A 1 311 ARG 311 364 364 ARG ARG A . n A 1 312 ASP 312 365 365 ASP ASP A . n A 1 313 LEU 313 366 366 LEU LEU A . n A 1 314 GLN 314 367 367 GLN GLN A . n A 1 315 ASN 315 368 368 ASN ASN A . n A 1 316 LEU 316 369 369 LEU LEU A . n A 1 317 MET 317 370 370 MET MET A . n A 1 318 SER 318 371 371 SER SER A . n A 1 319 TRP 319 372 372 TRP TRP A . n A 1 320 ARG 320 373 373 ARG ARG A . n A 1 321 PHE 321 374 374 PHE PHE A . n A 1 322 ILE 322 375 375 ILE ILE A . n A 1 323 MET 323 376 376 MET MET A . n A 1 324 ASP 324 377 377 ASP ASP A . n A 1 325 LEU 325 378 378 LEU LEU A . n A 1 326 VAL 326 379 379 VAL VAL A . n A 1 327 SER 327 380 380 SER SER A . n A 1 328 SER 328 381 381 SER SER A . n A 1 329 LEU 329 382 382 LEU LEU A . n A 1 330 SER 330 383 383 SER SER A . n A 1 331 ARG 331 384 384 ARG ARG A . n A 1 332 THR 332 385 385 THR THR A . n A 1 333 TYR 333 386 386 TYR TYR A . n A 1 334 LYS 334 387 387 LYS LYS A . n A 1 335 GLU 335 388 388 GLU GLU A . n A 1 336 SER 336 389 389 SER SER A . n A 1 337 ARG 337 390 390 ARG ARG A . n A 1 338 ASN 338 391 391 ASN ASN A . n A 1 339 ALA 339 392 392 ALA ALA A . n A 1 340 PHE 340 393 393 PHE PHE A . n A 1 341 ARG 341 394 394 ARG ARG A . n A 1 342 LYS 342 395 395 LYS LYS A . n A 1 343 ALA 343 396 396 ALA ALA A . n A 1 344 LEU 344 397 397 LEU LEU A . n A 1 345 TYR 345 398 398 TYR TYR A . n A 1 346 GLY 346 399 399 GLY GLY A . n A 1 347 THR 347 400 400 THR THR A . n A 1 348 THR 348 401 401 THR THR A . n A 1 349 SER 349 402 402 SER SER A . n A 1 350 GLU 350 403 403 GLU GLU A . n A 1 351 THR 351 404 404 THR THR A . n A 1 352 ALA 352 405 405 ALA ALA A . n A 1 353 THR 353 406 406 THR THR A . n A 1 354 TRP 354 407 407 TRP TRP A . n A 1 355 ARG 355 408 408 ARG ARG A . n A 1 356 ARG 356 409 409 ARG ARG A . n A 1 357 CYS 357 410 410 CYS CYS A . n A 1 358 ALA 358 411 411 ALA ALA A . n A 1 359 ASN 359 412 412 ASN ASN A . n A 1 360 TYR 360 413 413 TYR TYR A . n A 1 361 VAL 361 414 414 VAL VAL A . n A 1 362 ASN 362 415 415 ASN ASN A . n A 1 363 GLY 363 416 416 GLY GLY A . n A 1 364 ASN 364 417 417 ASN ASN A . n A 1 365 MET 365 418 418 MET MET A . n A 1 366 GLU 366 419 419 GLU GLU A . n A 1 367 ASN 367 420 420 ASN ASN A . n A 1 368 ALA 368 421 421 ALA ALA A . n A 1 369 VAL 369 422 422 VAL VAL A . n A 1 370 GLY 370 423 423 GLY GLY A . n A 1 371 ARG 371 424 424 ARG ARG A . n A 1 372 LEU 372 425 425 LEU LEU A . n A 1 373 TYR 373 426 426 TYR TYR A . n A 1 374 VAL 374 427 427 VAL VAL A . n A 1 375 GLU 375 428 428 GLU GLU A . n A 1 376 ALA 376 429 429 ALA ALA A . n A 1 377 ALA 377 430 430 ALA ALA A . n A 1 378 PHE 378 431 431 PHE PHE A . n A 1 379 ALA 379 432 432 ALA ALA A . n A 1 380 GLY 380 433 433 GLY GLY A . n A 1 381 GLU 381 434 434 GLU GLU A . n A 1 382 SER 382 435 435 SER SER A . n A 1 383 LYS 383 436 436 LYS LYS A . n A 1 384 HIS 384 437 437 HIS HIS A . n A 1 385 VAL 385 438 438 VAL VAL A . n A 1 386 VAL 386 439 439 VAL VAL A . n A 1 387 GLU 387 440 440 GLU GLU A . n A 1 388 ASP 388 441 441 ASP ASP A . n A 1 389 LEU 389 442 442 LEU LEU A . n A 1 390 ILE 390 443 443 ILE ILE A . n A 1 391 ALA 391 444 444 ALA ALA A . n A 1 392 GLN 392 445 445 GLN GLN A . n A 1 393 ILE 393 446 446 ILE ILE A . n A 1 394 ARG 394 447 447 ARG ARG A . n A 1 395 GLU 395 448 448 GLU GLU A . n A 1 396 VAL 396 449 449 VAL VAL A . n A 1 397 PHE 397 450 450 PHE PHE A . n A 1 398 ILE 398 451 451 ILE ILE A . n A 1 399 GLN 399 452 452 GLN GLN A . n A 1 400 THR 400 453 453 THR THR A . n A 1 401 LEU 401 454 454 LEU LEU A . n A 1 402 ASP 402 455 455 ASP ASP A . n A 1 403 ASP 403 456 456 ASP ASP A . n A 1 404 LEU 404 457 457 LEU LEU A . n A 1 405 THR 405 458 458 THR THR A . n A 1 406 TRP 406 459 459 TRP TRP A . n A 1 407 MET 407 460 460 MET MET A . n A 1 408 ASP 408 461 461 ASP ASP A . n A 1 409 ALA 409 462 462 ALA ALA A . n A 1 410 GLU 410 463 463 GLU GLU A . n A 1 411 THR 411 464 464 THR THR A . n A 1 412 LYS 412 465 465 LYS LYS A . n A 1 413 LYS 413 466 466 LYS LYS A . n A 1 414 ARG 414 467 467 ARG ARG A . n A 1 415 ALA 415 468 468 ALA ALA A . n A 1 416 GLU 416 469 469 GLU GLU A . n A 1 417 GLU 417 470 470 GLU GLU A . n A 1 418 LYS 418 471 471 LYS LYS A . n A 1 419 ALA 419 472 472 ALA ALA A . n A 1 420 LEU 420 473 473 LEU LEU A . n A 1 421 ALA 421 474 474 ALA ALA A . n A 1 422 ILE 422 475 475 ILE ILE A . n A 1 423 LYS 423 476 476 LYS LYS A . n A 1 424 GLU 424 477 477 GLU GLU A . n A 1 425 ARG 425 478 478 ARG ARG A . n A 1 426 ILE 426 479 479 ILE ILE A . n A 1 427 GLY 427 480 480 GLY GLY A . n A 1 428 TYR 428 481 481 TYR TYR A . n A 1 429 PRO 429 482 482 PRO PRO A . n A 1 430 ASP 430 483 483 ASP ASP A . n A 1 431 ASP 431 484 484 ASP ASP A . n A 1 432 ILE 432 485 485 ILE ILE A . n A 1 433 VAL 433 486 486 VAL VAL A . n A 1 434 SER 434 487 487 SER SER A . n A 1 435 ASN 435 488 488 ASN ASN A . n A 1 436 ASP 436 489 489 ASP ASP A . n A 1 437 ASN 437 490 490 ASN ASN A . n A 1 438 LYS 438 491 491 LYS LYS A . n A 1 439 LEU 439 492 492 LEU LEU A . n A 1 440 ASN 440 493 493 ASN ASN A . n A 1 441 ASN 441 494 494 ASN ASN A . n A 1 442 GLU 442 495 495 GLU GLU A . n A 1 443 TYR 443 496 496 TYR TYR A . n A 1 444 LEU 444 497 497 LEU LEU A . n A 1 445 GLU 445 498 498 GLU GLU A . n A 1 446 LEU 446 499 499 LEU LEU A . n A 1 447 ASN 447 500 500 ASN ASN A . n A 1 448 TYR 448 501 501 TYR TYR A . n A 1 449 LYS 449 502 502 LYS LYS A . n A 1 450 GLU 450 503 503 GLU GLU A . n A 1 451 ASP 451 504 504 ASP ASP A . n A 1 452 GLU 452 505 505 GLU GLU A . n A 1 453 TYR 453 506 506 TYR TYR A . n A 1 454 PHE 454 507 507 PHE PHE A . n A 1 455 GLU 455 508 508 GLU GLU A . n A 1 456 ASN 456 509 509 ASN ASN A . n A 1 457 ILE 457 510 510 ILE ILE A . n A 1 458 ILE 458 511 511 ILE ILE A . n A 1 459 GLN 459 512 512 GLN GLN A . n A 1 460 ASN 460 513 513 ASN ASN A . n A 1 461 LEU 461 514 514 LEU LEU A . n A 1 462 LYS 462 515 515 LYS LYS A . n A 1 463 PHE 463 516 516 PHE PHE A . n A 1 464 SER 464 517 517 SER SER A . n A 1 465 GLN 465 518 518 GLN GLN A . n A 1 466 SER 466 519 519 SER SER A . n A 1 467 LYS 467 520 520 LYS LYS A . n A 1 468 GLN 468 521 521 GLN GLN A . n A 1 469 LEU 469 522 522 LEU LEU A . n A 1 470 LYS 470 523 523 LYS LYS A . n A 1 471 LYS 471 524 524 LYS LYS A . n A 1 472 LEU 472 525 525 LEU LEU A . n A 1 473 ARG 473 526 526 ARG ARG A . n A 1 474 GLU 474 527 527 GLU GLU A . n A 1 475 LYS 475 528 528 LYS LYS A . n A 1 476 VAL 476 529 529 VAL VAL A . n A 1 477 ASP 477 530 530 ASP ASP A . n A 1 478 LYS 478 531 531 LYS LYS A . n A 1 479 ASP 479 532 532 ASP ASP A . n A 1 480 GLU 480 533 533 GLU GLU A . n A 1 481 TRP 481 534 534 TRP TRP A . n A 1 482 ILE 482 535 535 ILE ILE A . n A 1 483 SER 483 536 536 SER SER A . n A 1 484 GLY 484 537 537 GLY GLY A . n A 1 485 ALA 485 538 538 ALA ALA A . n A 1 486 ALA 486 539 539 ALA ALA A . n A 1 487 VAL 487 540 540 VAL VAL A . n A 1 488 VAL 488 541 541 VAL VAL A . n A 1 489 ASN 489 542 542 ASN ASN A . n A 1 490 ALA 490 543 543 ALA ALA A . n A 1 491 PHE 491 544 544 PHE PHE A . n A 1 492 TYR 492 545 545 TYR TYR A . n A 1 493 SER 493 546 546 SER SER A . n A 1 494 SER 494 547 547 SER SER A . n A 1 495 GLY 495 548 548 GLY GLY A . n A 1 496 ARG 496 549 549 ARG ARG A . n A 1 497 ASN 497 550 550 ASN ASN A . n A 1 498 GLN 498 551 551 GLN GLN A . n A 1 499 ILE 499 552 552 ILE ILE A . n A 1 500 VAL 500 553 553 VAL VAL A . n A 1 501 PHE 501 554 554 PHE PHE A . n A 1 502 PRO 502 555 555 PRO PRO A . n A 1 503 ALA 503 556 556 ALA ALA A . n A 1 504 GLY 504 557 557 GLY GLY A . n A 1 505 ILE 505 558 558 ILE ILE A . n A 1 506 LEU 506 559 559 LEU LEU A . n A 1 507 GLN 507 560 560 GLN GLN A . n A 1 508 PRO 508 561 561 PRO PRO A . n A 1 509 PRO 509 562 562 PRO PRO A . n A 1 510 PHE 510 563 563 PHE PHE A . n A 1 511 PHE 511 564 564 PHE PHE A . n A 1 512 SER 512 565 565 SER SER A . n A 1 513 ALA 513 566 566 ALA ALA A . n A 1 514 GLN 514 567 567 GLN GLN A . n A 1 515 GLN 515 568 568 GLN GLN A . n A 1 516 SER 516 569 569 SER SER A . n A 1 517 ASN 517 570 570 ASN ASN A . n A 1 518 SER 518 571 571 SER SER A . n A 1 519 LEU 519 572 572 LEU LEU A . n A 1 520 ASN 520 573 573 ASN ASN A . n A 1 521 TYR 521 574 574 TYR TYR A . n A 1 522 GLY 522 575 575 GLY GLY A . n A 1 523 GLY 523 576 576 GLY GLY A . n A 1 524 ILE 524 577 577 ILE ILE A . n A 1 525 GLY 525 578 578 GLY GLY A . n A 1 526 MET 526 579 579 MET MET A . n A 1 527 VAL 527 580 580 VAL VAL A . n A 1 528 ILE 528 581 581 ILE ILE A . n A 1 529 GLY 529 582 582 GLY GLY A . n A 1 530 HIS 530 583 583 HIS HIS A . n A 1 531 GLU 531 584 584 GLU GLU A . n A 1 532 ILE 532 585 585 ILE ILE A . n A 1 533 THR 533 586 586 THR THR A . n A 1 534 HIS 534 587 587 HIS HIS A . n A 1 535 GLY 535 588 588 GLY GLY A . n A 1 536 PHE 536 589 589 PHE PHE A . n A 1 537 ASP 537 590 590 ASP ASP A . n A 1 538 ASP 538 591 591 ASP ASP A . n A 1 539 ASN 539 592 592 ASN ASN A . n A 1 540 GLY 540 593 593 GLY GLY A . n A 1 541 ARG 541 594 594 ARG ARG A . n A 1 542 ASN 542 595 595 ASN ASN A . n A 1 543 PHE 543 596 596 PHE PHE A . n A 1 544 ASN 544 597 597 ASN ASN A . n A 1 545 LYS 545 598 598 LYS LYS A . n A 1 546 ASP 546 599 599 ASP ASP A . n A 1 547 GLY 547 600 600 GLY GLY A . n A 1 548 ASP 548 601 601 ASP ASP A . n A 1 549 LEU 549 602 602 LEU LEU A . n A 1 550 VAL 550 603 603 VAL VAL A . n A 1 551 ASP 551 604 604 ASP ASP A . n A 1 552 TRP 552 605 605 TRP TRP A . n A 1 553 TRP 553 606 606 TRP TRP A . n A 1 554 THR 554 607 607 THR THR A . n A 1 555 GLN 555 608 608 GLN GLN A . n A 1 556 GLN 556 609 609 GLN GLN A . n A 1 557 SER 557 610 610 SER SER A . n A 1 558 ALA 558 611 611 ALA ALA A . n A 1 559 SER 559 612 612 SER SER A . n A 1 560 ASN 560 613 613 ASN ASN A . n A 1 561 PHE 561 614 614 PHE PHE A . n A 1 562 LYS 562 615 615 LYS LYS A . n A 1 563 GLU 563 616 616 GLU GLU A . n A 1 564 GLN 564 617 617 GLN GLN A . n A 1 565 SER 565 618 618 SER SER A . n A 1 566 GLN 566 619 619 GLN GLN A . n A 1 567 CYS 567 620 620 CYS CYS A . n A 1 568 MET 568 621 621 MET MET A . n A 1 569 VAL 569 622 622 VAL VAL A . n A 1 570 TYR 570 623 623 TYR TYR A . n A 1 571 GLN 571 624 624 GLN GLN A . n A 1 572 TYR 572 625 625 TYR TYR A . n A 1 573 GLY 573 626 626 GLY GLY A . n A 1 574 ASN 574 627 627 ASN ASN A . n A 1 575 PHE 575 628 628 PHE PHE A . n A 1 576 SER 576 629 629 SER SER A . n A 1 577 TRP 577 630 630 TRP TRP A . n A 1 578 ASP 578 631 631 ASP ASP A . n A 1 579 LEU 579 632 632 LEU LEU A . n A 1 580 ALA 580 633 633 ALA ALA A . n A 1 581 GLY 581 634 634 GLY GLY A . n A 1 582 GLY 582 635 635 GLY GLY A . n A 1 583 GLN 583 636 636 GLN GLN A . n A 1 584 HIS 584 637 637 HIS HIS A . n A 1 585 LEU 585 638 638 LEU LEU A . n A 1 586 ASN 586 639 639 ASN ASN A . n A 1 587 GLY 587 640 640 GLY GLY A . n A 1 588 ILE 588 641 641 ILE ILE A . n A 1 589 ASN 589 642 642 ASN ASN A . n A 1 590 THR 590 643 643 THR THR A . n A 1 591 LEU 591 644 644 LEU LEU A . n A 1 592 GLY 592 645 645 GLY GLY A . n A 1 593 GLU 593 646 646 GLU GLU A . n A 1 594 ASN 594 647 647 ASN ASN A . n A 1 595 ILE 595 648 648 ILE ILE A . n A 1 596 ALA 596 649 649 ALA ALA A . n A 1 597 ASP 597 650 650 ASP ASP A . n A 1 598 ASN 598 651 651 ASN ASN A . n A 1 599 GLY 599 652 652 GLY GLY A . n A 1 600 GLY 600 653 653 GLY GLY A . n A 1 601 LEU 601 654 654 LEU LEU A . n A 1 602 GLY 602 655 655 GLY GLY A . n A 1 603 GLN 603 656 656 GLN GLN A . n A 1 604 ALA 604 657 657 ALA ALA A . n A 1 605 TYR 605 658 658 TYR TYR A . n A 1 606 ARG 606 659 659 ARG ARG A . n A 1 607 ALA 607 660 660 ALA ALA A . n A 1 608 TYR 608 661 661 TYR TYR A . n A 1 609 GLN 609 662 662 GLN GLN A . n A 1 610 ASN 610 663 663 ASN ASN A . n A 1 611 TYR 611 664 664 TYR TYR A . n A 1 612 ILE 612 665 665 ILE ILE A . n A 1 613 LYS 613 666 666 LYS LYS A . n A 1 614 LYS 614 667 667 LYS LYS A . n A 1 615 ASN 615 668 668 ASN ASN A . n A 1 616 GLY 616 669 669 GLY GLY A . n A 1 617 GLU 617 670 670 GLU GLU A . n A 1 618 GLU 618 671 671 GLU GLU A . n A 1 619 LYS 619 672 672 LYS LYS A . n A 1 620 LEU 620 673 673 LEU LEU A . n A 1 621 LEU 621 674 674 LEU LEU A . n A 1 622 PRO 622 675 675 PRO PRO A . n A 1 623 GLY 623 676 676 GLY GLY A . n A 1 624 LEU 624 677 677 LEU LEU A . n A 1 625 ASP 625 678 678 ASP ASP A . n A 1 626 LEU 626 679 679 LEU LEU A . n A 1 627 ASN 627 680 680 ASN ASN A . n A 1 628 HIS 628 681 681 HIS HIS A . n A 1 629 LYS 629 682 682 LYS LYS A . n A 1 630 GLN 630 683 683 GLN GLN A . n A 1 631 LEU 631 684 684 LEU LEU A . n A 1 632 PHE 632 685 685 PHE PHE A . n A 1 633 PHE 633 686 686 PHE PHE A . n A 1 634 LEU 634 687 687 LEU LEU A . n A 1 635 ASN 635 688 688 ASN ASN A . n A 1 636 PHE 636 689 689 PHE PHE A . n A 1 637 ALA 637 690 690 ALA ALA A . n A 1 638 GLN 638 691 691 GLN GLN A . n A 1 639 VAL 639 692 692 VAL VAL A . n A 1 640 TRP 640 693 693 TRP TRP A . n A 1 641 CYS 641 694 694 CYS CYS A . n A 1 642 GLY 642 695 695 GLY GLY A . n A 1 643 THR 643 696 696 THR THR A . n A 1 644 TYR 644 697 697 TYR TYR A . n A 1 645 ARG 645 698 698 ARG ARG A . n A 1 646 PRO 646 699 699 PRO PRO A . n A 1 647 GLU 647 700 700 GLU GLU A . n A 1 648 TYR 648 701 701 TYR TYR A . n A 1 649 ALA 649 702 702 ALA ALA A . n A 1 650 VAL 650 703 703 VAL VAL A . n A 1 651 ASN 651 704 704 ASN ASN A . n A 1 652 SER 652 705 705 SER SER A . n A 1 653 ILE 653 706 706 ILE ILE A . n A 1 654 LYS 654 707 707 LYS LYS A . n A 1 655 THR 655 708 708 THR THR A . n A 1 656 ASP 656 709 709 ASP ASP A . n A 1 657 VAL 657 710 710 VAL VAL A . n A 1 658 HIS 658 711 711 HIS HIS A . n A 1 659 SER 659 712 712 SER SER A . n A 1 660 PRO 660 713 713 PRO PRO A . n A 1 661 GLY 661 714 714 GLY GLY A . n A 1 662 ASN 662 715 715 ASN ASN A . n A 1 663 PHE 663 716 716 PHE PHE A . n A 1 664 ARG 664 717 717 ARG ARG A . n A 1 665 ILE 665 718 718 ILE ILE A . n A 1 666 ILE 666 719 719 ILE ILE A . n A 1 667 GLY 667 720 720 GLY GLY A . n A 1 668 THR 668 721 721 THR THR A . n A 1 669 LEU 669 722 722 LEU LEU A . n A 1 670 GLN 670 723 723 GLN GLN A . n A 1 671 ASN 671 724 724 ASN ASN A . n A 1 672 SER 672 725 725 SER SER A . n A 1 673 ALA 673 726 726 ALA ALA A . n A 1 674 GLU 674 727 727 GLU GLU A . n A 1 675 PHE 675 728 728 PHE PHE A . n A 1 676 SER 676 729 729 SER SER A . n A 1 677 GLU 677 730 730 GLU GLU A . n A 1 678 ALA 678 731 731 ALA ALA A . n A 1 679 PHE 679 732 732 PHE PHE A . n A 1 680 HIS 680 733 733 HIS HIS A . n A 1 681 CYS 681 734 734 CYS CYS A . n A 1 682 ARG 682 735 735 ARG ARG A . n A 1 683 LYS 683 736 736 LYS LYS A . n A 1 684 ASN 684 737 737 ASN ASN A . n A 1 685 SER 685 738 738 SER SER A . n A 1 686 TYR 686 739 739 TYR TYR A . n A 1 687 MET 687 740 740 MET MET A . n A 1 688 ASN 688 741 741 ASN ASN A . n A 1 689 PRO 689 742 742 PRO PRO A . n A 1 690 GLU 690 743 743 GLU GLU A . n A 1 691 LYS 691 744 744 LYS LYS A . n A 1 692 LYS 692 745 745 LYS LYS A . n A 1 693 CYS 693 746 746 CYS CYS A . n A 1 694 ARG 694 747 747 ARG ARG A . n A 1 695 VAL 695 748 748 VAL VAL A . n A 1 696 TRP 696 749 749 TRP TRP A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 752 752 NAG NAG A . C 2 NAG 1 753 753 NAG NAG A . D 2 NAG 1 754 754 NAG NAG A . E 3 ZN 1 800 1 ZN ZN A . F 4 ACT 1 801 1 ACT ACT A . G 5 STS 1 900 1 STS STS A . H 6 HOH 1 901 1 HOH HOH A . H 6 HOH 2 902 2 HOH HOH A . H 6 HOH 3 903 3 HOH HOH A . H 6 HOH 4 904 4 HOH HOH A . H 6 HOH 5 905 5 HOH HOH A . H 6 HOH 6 906 6 HOH HOH A . H 6 HOH 7 907 7 HOH HOH A . H 6 HOH 8 908 8 HOH HOH A . H 6 HOH 9 909 9 HOH HOH A . H 6 HOH 10 910 10 HOH HOH A . H 6 HOH 11 911 11 HOH HOH A . H 6 HOH 12 912 12 HOH HOH A . H 6 HOH 13 913 13 HOH HOH A . H 6 HOH 14 914 14 HOH HOH A . H 6 HOH 15 915 15 HOH HOH A . H 6 HOH 16 916 16 HOH HOH A . H 6 HOH 17 917 17 HOH HOH A . H 6 HOH 18 918 18 HOH HOH A . H 6 HOH 19 919 20 HOH HOH A . H 6 HOH 20 920 21 HOH HOH A . H 6 HOH 21 921 22 HOH HOH A . H 6 HOH 22 922 23 HOH HOH A . H 6 HOH 23 923 24 HOH HOH A . H 6 HOH 24 924 25 HOH HOH A . H 6 HOH 25 925 26 HOH HOH A . H 6 HOH 26 926 27 HOH HOH A . H 6 HOH 27 927 28 HOH HOH A . H 6 HOH 28 928 29 HOH HOH A . H 6 HOH 29 929 30 HOH HOH A . H 6 HOH 30 930 31 HOH HOH A . H 6 HOH 31 931 33 HOH HOH A . H 6 HOH 32 932 34 HOH HOH A . H 6 HOH 33 933 35 HOH HOH A . H 6 HOH 34 934 36 HOH HOH A . H 6 HOH 35 935 37 HOH HOH A . H 6 HOH 36 936 38 HOH HOH A . H 6 HOH 37 937 39 HOH HOH A . H 6 HOH 38 938 40 HOH HOH A . H 6 HOH 39 939 41 HOH HOH A . H 6 HOH 40 940 42 HOH HOH A . H 6 HOH 41 941 43 HOH HOH A . H 6 HOH 42 942 44 HOH HOH A . H 6 HOH 43 943 45 HOH HOH A . H 6 HOH 44 944 46 HOH HOH A . H 6 HOH 45 945 47 HOH HOH A . H 6 HOH 46 946 48 HOH HOH A . H 6 HOH 47 947 49 HOH HOH A . H 6 HOH 48 948 50 HOH HOH A . H 6 HOH 49 949 51 HOH HOH A . H 6 HOH 50 950 52 HOH HOH A . H 6 HOH 51 951 53 HOH HOH A . H 6 HOH 52 952 54 HOH HOH A . H 6 HOH 53 953 55 HOH HOH A . H 6 HOH 54 954 56 HOH HOH A . H 6 HOH 55 955 57 HOH HOH A . H 6 HOH 56 956 58 HOH HOH A . H 6 HOH 57 957 59 HOH HOH A . H 6 HOH 58 958 60 HOH HOH A . H 6 HOH 59 959 61 HOH HOH A . H 6 HOH 60 960 62 HOH HOH A . H 6 HOH 61 961 63 HOH HOH A . H 6 HOH 62 962 64 HOH HOH A . H 6 HOH 63 963 65 HOH HOH A . H 6 HOH 64 964 66 HOH HOH A . H 6 HOH 65 965 67 HOH HOH A . H 6 HOH 66 966 68 HOH HOH A . H 6 HOH 67 967 69 HOH HOH A . H 6 HOH 68 968 70 HOH HOH A . H 6 HOH 69 969 72 HOH HOH A . H 6 HOH 70 970 73 HOH HOH A . H 6 HOH 71 971 74 HOH HOH A . H 6 HOH 72 972 75 HOH HOH A . H 6 HOH 73 973 76 HOH HOH A . H 6 HOH 74 974 77 HOH HOH A . H 6 HOH 75 975 78 HOH HOH A . H 6 HOH 76 976 79 HOH HOH A . H 6 HOH 77 977 80 HOH HOH A . H 6 HOH 78 978 81 HOH HOH A . H 6 HOH 79 979 82 HOH HOH A . H 6 HOH 80 980 83 HOH HOH A . H 6 HOH 81 981 84 HOH HOH A . H 6 HOH 82 982 85 HOH HOH A . H 6 HOH 83 983 86 HOH HOH A . H 6 HOH 84 984 87 HOH HOH A . H 6 HOH 85 985 88 HOH HOH A . H 6 HOH 86 986 89 HOH HOH A . H 6 HOH 87 987 90 HOH HOH A . H 6 HOH 88 988 91 HOH HOH A . H 6 HOH 89 989 92 HOH HOH A . H 6 HOH 90 990 93 HOH HOH A . H 6 HOH 91 991 94 HOH HOH A . H 6 HOH 92 992 95 HOH HOH A . H 6 HOH 93 993 96 HOH HOH A . H 6 HOH 94 994 97 HOH HOH A . H 6 HOH 95 995 98 HOH HOH A . H 6 HOH 96 996 99 HOH HOH A . H 6 HOH 97 997 100 HOH HOH A . H 6 HOH 98 998 101 HOH HOH A . H 6 HOH 99 999 102 HOH HOH A . H 6 HOH 100 1000 103 HOH HOH A . H 6 HOH 101 1001 104 HOH HOH A . H 6 HOH 102 1002 105 HOH HOH A . H 6 HOH 103 1003 106 HOH HOH A . H 6 HOH 104 1004 107 HOH HOH A . H 6 HOH 105 1005 108 HOH HOH A . H 6 HOH 106 1006 109 HOH HOH A . H 6 HOH 107 1007 110 HOH HOH A . H 6 HOH 108 1008 111 HOH HOH A . H 6 HOH 109 1009 112 HOH HOH A . H 6 HOH 110 1010 113 HOH HOH A . H 6 HOH 111 1011 114 HOH HOH A . H 6 HOH 112 1012 115 HOH HOH A . H 6 HOH 113 1013 116 HOH HOH A . H 6 HOH 114 1014 117 HOH HOH A . H 6 HOH 115 1015 118 HOH HOH A . H 6 HOH 116 1016 119 HOH HOH A . H 6 HOH 117 1017 120 HOH HOH A . H 6 HOH 118 1018 121 HOH HOH A . H 6 HOH 119 1019 122 HOH HOH A . H 6 HOH 120 1020 123 HOH HOH A . H 6 HOH 121 1021 124 HOH HOH A . H 6 HOH 122 1022 125 HOH HOH A . H 6 HOH 123 1023 126 HOH HOH A . H 6 HOH 124 1024 127 HOH HOH A . H 6 HOH 125 1025 128 HOH HOH A . H 6 HOH 126 1026 129 HOH HOH A . H 6 HOH 127 1027 130 HOH HOH A . H 6 HOH 128 1028 131 HOH HOH A . H 6 HOH 129 1029 132 HOH HOH A . H 6 HOH 130 1030 133 HOH HOH A . H 6 HOH 131 1031 134 HOH HOH A . H 6 HOH 132 1032 135 HOH HOH A . H 6 HOH 133 1033 136 HOH HOH A . H 6 HOH 134 1034 137 HOH HOH A . H 6 HOH 135 1035 138 HOH HOH A . H 6 HOH 136 1036 139 HOH HOH A . H 6 HOH 137 1037 140 HOH HOH A . H 6 HOH 138 1038 141 HOH HOH A . H 6 HOH 139 1039 142 HOH HOH A . H 6 HOH 140 1040 143 HOH HOH A . H 6 HOH 141 1041 144 HOH HOH A . H 6 HOH 142 1042 145 HOH HOH A . H 6 HOH 143 1043 146 HOH HOH A . H 6 HOH 144 1044 147 HOH HOH A . H 6 HOH 145 1045 148 HOH HOH A . H 6 HOH 146 1046 149 HOH HOH A . H 6 HOH 147 1047 150 HOH HOH A . H 6 HOH 148 1048 151 HOH HOH A . H 6 HOH 149 1049 152 HOH HOH A . H 6 HOH 150 1050 153 HOH HOH A . H 6 HOH 151 1051 154 HOH HOH A . H 6 HOH 152 1052 155 HOH HOH A . H 6 HOH 153 1053 156 HOH HOH A . H 6 HOH 154 1054 157 HOH HOH A . H 6 HOH 155 1055 158 HOH HOH A . H 6 HOH 156 1056 159 HOH HOH A . H 6 HOH 157 1057 160 HOH HOH A . H 6 HOH 158 1058 161 HOH HOH A . H 6 HOH 159 1059 162 HOH HOH A . H 6 HOH 160 1060 163 HOH HOH A . H 6 HOH 161 1061 164 HOH HOH A . H 6 HOH 162 1062 165 HOH HOH A . H 6 HOH 163 1063 166 HOH HOH A . H 6 HOH 164 1064 167 HOH HOH A . H 6 HOH 165 1065 168 HOH HOH A . H 6 HOH 166 1066 169 HOH HOH A . H 6 HOH 167 1067 170 HOH HOH A . H 6 HOH 168 1068 171 HOH HOH A . H 6 HOH 169 1069 172 HOH HOH A . H 6 HOH 170 1070 173 HOH HOH A . H 6 HOH 171 1071 174 HOH HOH A . H 6 HOH 172 1072 175 HOH HOH A . H 6 HOH 173 1073 176 HOH HOH A . H 6 HOH 174 1074 177 HOH HOH A . H 6 HOH 175 1075 178 HOH HOH A . H 6 HOH 176 1076 179 HOH HOH A . H 6 HOH 177 1077 180 HOH HOH A . H 6 HOH 178 1078 181 HOH HOH A . H 6 HOH 179 1079 182 HOH HOH A . H 6 HOH 180 1080 183 HOH HOH A . H 6 HOH 181 1081 184 HOH HOH A . H 6 HOH 182 1082 185 HOH HOH A . H 6 HOH 183 1083 186 HOH HOH A . H 6 HOH 184 1084 187 HOH HOH A . H 6 HOH 185 1085 188 HOH HOH A . H 6 HOH 186 1086 189 HOH HOH A . H 6 HOH 187 1087 190 HOH HOH A . H 6 HOH 188 1088 191 HOH HOH A . H 6 HOH 189 1089 192 HOH HOH A . H 6 HOH 190 1090 193 HOH HOH A . H 6 HOH 191 1091 194 HOH HOH A . H 6 HOH 192 1092 195 HOH HOH A . H 6 HOH 193 1093 196 HOH HOH A . H 6 HOH 194 1094 197 HOH HOH A . H 6 HOH 195 1095 198 HOH HOH A . H 6 HOH 196 1096 199 HOH HOH A . H 6 HOH 197 1097 200 HOH HOH A . H 6 HOH 198 1098 201 HOH HOH A . H 6 HOH 199 1099 202 HOH HOH A . H 6 HOH 200 1100 203 HOH HOH A . H 6 HOH 201 1101 204 HOH HOH A . H 6 HOH 202 1102 205 HOH HOH A . H 6 HOH 203 1103 206 HOH HOH A . H 6 HOH 204 1104 207 HOH HOH A . H 6 HOH 205 1105 208 HOH HOH A . H 6 HOH 206 1106 209 HOH HOH A . H 6 HOH 207 1107 210 HOH HOH A . H 6 HOH 208 1108 211 HOH HOH A . H 6 HOH 209 1109 212 HOH HOH A . H 6 HOH 210 1110 213 HOH HOH A . H 6 HOH 211 1111 214 HOH HOH A . H 6 HOH 212 1112 215 HOH HOH A . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 91 A ASN 144 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 271 A ASN 324 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 574 A ASN 627 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 534 ? A HIS 587 ? 1_555 ZN ? E ZN . ? A ZN 800 ? 1_555 NE2 ? A HIS 530 ? A HIS 583 ? 1_555 86.5 ? 2 NE2 ? A HIS 534 ? A HIS 587 ? 1_555 ZN ? E ZN . ? A ZN 800 ? 1_555 OE1 ? A GLU 593 ? A GLU 646 ? 1_555 112.3 ? 3 NE2 ? A HIS 530 ? A HIS 583 ? 1_555 ZN ? E ZN . ? A ZN 800 ? 1_555 OE1 ? A GLU 593 ? A GLU 646 ? 1_555 91.1 ? 4 NE2 ? A HIS 534 ? A HIS 587 ? 1_555 ZN ? E ZN . ? A ZN 800 ? 1_555 S10 ? G STS . ? A STS 900 ? 1_555 126.0 ? 5 NE2 ? A HIS 530 ? A HIS 583 ? 1_555 ZN ? E ZN . ? A ZN 800 ? 1_555 S10 ? G STS . ? A STS 900 ? 1_555 120.5 ? 6 OE1 ? A GLU 593 ? A GLU 646 ? 1_555 ZN ? E ZN . ? A ZN 800 ? 1_555 S10 ? G STS . ? A STS 900 ? 1_555 112.7 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2005-06-07 2 'Structure model' 1 1 2008-04-30 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal REFMAC refinement 5.0 ? 1 DENZO 'data reduction' . ? 2 SCALEPACK 'data scaling' . ? 3 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 O A GLN 518 ? ? CD2 A LEU 522 ? ? 1.42 2 1 NZ A LYS 209 ? ? CD1 A TYR 299 ? ? 1.61 3 1 NH1 A ARG 256 ? ? O A PRO 262 ? ? 1.73 4 1 O A GLN 257 ? ? O A HOH 937 ? ? 1.85 5 1 CE A LYS 209 ? ? CE1 A TYR 299 ? ? 1.93 6 1 O A LYS 353 ? ? CD1 A ILE 357 ? ? 1.94 7 1 OH A TYR 661 ? ? OE1 A GLU 671 ? ? 2.03 8 1 CE A MET 579 ? ? O A HOH 909 ? ? 2.10 9 1 NH2 A ARG 140 ? ? OE1 A GLU 503 ? ? 2.11 10 1 NZ A LYS 209 ? ? CE1 A TYR 299 ? ? 2.13 11 1 O A ASP 530 ? ? NH2 A ARG 549 ? ? 2.14 12 1 OG A SER 612 ? ? O A HOH 1036 ? ? 2.15 13 1 OH A TYR 496 ? ? O A HOH 1003 ? ? 2.16 14 1 O A TYR 177 ? ? N A SER 180 ? ? 2.17 15 1 OD2 A ASP 604 ? ? O A HOH 1037 ? ? 2.19 # loop_ _pdbx_validate_symm_contact.id _pdbx_validate_symm_contact.PDB_model_num _pdbx_validate_symm_contact.auth_atom_id_1 _pdbx_validate_symm_contact.auth_asym_id_1 _pdbx_validate_symm_contact.auth_comp_id_1 _pdbx_validate_symm_contact.auth_seq_id_1 _pdbx_validate_symm_contact.PDB_ins_code_1 _pdbx_validate_symm_contact.label_alt_id_1 _pdbx_validate_symm_contact.site_symmetry_1 _pdbx_validate_symm_contact.auth_atom_id_2 _pdbx_validate_symm_contact.auth_asym_id_2 _pdbx_validate_symm_contact.auth_comp_id_2 _pdbx_validate_symm_contact.auth_seq_id_2 _pdbx_validate_symm_contact.PDB_ins_code_2 _pdbx_validate_symm_contact.label_alt_id_2 _pdbx_validate_symm_contact.site_symmetry_2 _pdbx_validate_symm_contact.dist 1 1 OE1 A GLN 175 ? ? 1_555 O A ARG 260 ? ? 5_555 1.52 2 1 OE1 A GLN 175 ? ? 1_555 C A ARG 260 ? ? 5_555 1.58 3 1 OE1 A GLN 175 ? ? 1_555 N A LEU 261 ? ? 5_555 1.84 4 1 OE1 A GLN 175 ? ? 1_555 CA A LEU 261 ? ? 5_555 1.88 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ALA A 179 ? ? -34.67 -91.00 2 1 LEU A 199 ? ? 67.11 -63.51 3 1 ARG A 260 ? ? 32.66 79.82 4 1 PHE A 311 ? ? -145.82 56.66 5 1 ASN A 316 ? ? 71.79 -55.74 6 1 LYS A 318 ? ? -151.33 -95.30 7 1 PRO A 319 ? ? -99.03 -141.59 8 1 ASN A 339 ? ? -44.47 -5.53 9 1 ALA A 347 ? ? -143.63 46.68 10 1 THR A 359 ? ? -55.35 -6.61 11 1 MET A 376 ? ? -17.39 -51.78 12 1 LEU A 382 ? ? -102.09 -166.80 13 1 MET A 418 ? ? -143.06 55.91 14 1 ASN A 550 ? ? 39.39 58.86 15 1 ALA A 556 ? ? -29.50 -49.58 16 1 ASN A 737 ? ? 89.51 1.73 17 1 VAL A 748 ? ? -118.70 -71.94 # loop_ _pdbx_validate_peptide_omega.id _pdbx_validate_peptide_omega.PDB_model_num _pdbx_validate_peptide_omega.auth_comp_id_1 _pdbx_validate_peptide_omega.auth_asym_id_1 _pdbx_validate_peptide_omega.auth_seq_id_1 _pdbx_validate_peptide_omega.PDB_ins_code_1 _pdbx_validate_peptide_omega.label_alt_id_1 _pdbx_validate_peptide_omega.auth_comp_id_2 _pdbx_validate_peptide_omega.auth_asym_id_2 _pdbx_validate_peptide_omega.auth_seq_id_2 _pdbx_validate_peptide_omega.PDB_ins_code_2 _pdbx_validate_peptide_omega.label_alt_id_2 _pdbx_validate_peptide_omega.omega 1 1 TRP A 181 ? ? THR A 182 ? ? 139.40 2 1 PRO A 319 ? ? PHE A 320 ? ? -146.22 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'ZINC ION' ZN 4 'ACETATE ION' ACT 5 '2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM' STS 6 water HOH #