data_1XLU # _entry.id 1XLU # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.286 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 1XLU RCSB RCSB030492 WWPDB D_1000030492 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1POI . unspecified PDB 1POM . unspecified PDB 1POP . unspecified PDB 1POQ . unspecified PDB 1XLV . unspecified PDB 1XLW . unspecified # _pdbx_database_status.entry_id 1XLU _pdbx_database_status.status_code REL _pdbx_database_status.recvd_initial_deposition_date 2004-09-30 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry N _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Nachon, F.' 1 'Asojo, O.A.' 2 'Borgstahl, G.E.O.' 3 'Masson, P.' 4 'Lockridge, O.' 5 # loop_ _citation.id _citation.title _citation.journal_abbrev _citation.journal_volume _citation.page_first _citation.page_last _citation.year _citation.journal_id_ASTM _citation.country _citation.journal_id_ISSN _citation.journal_id_CSD _citation.book_publisher _citation.pdbx_database_id_PubMed _citation.pdbx_database_id_DOI primary ;Role of Water in Aging of Human Butyrylcholinesterase Inhibited by Echothiophate: The Crystal Structure Suggests Two Alternative Mechanisms of Aging ; Biochemistry 44 1154 1162 2005 BICHAW US 0006-2960 0033 ? 15667209 10.1021/bi048238d 1 ;Engineering of a monomeric and low-glycosylated form of human butyrylcholinesterase: expression, purification, characterization and crystallization ; Eur.J.Biochem. 269 630 666 2002 EJBCAI IX 0014-2956 0262 ? ? ? 2 'Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products' J.Biol.Chem. 278 41141 41147 2003 JBCHA3 US 0021-9258 0071 ? ? ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Nachon, F.' 1 primary 'Asojo, O.A.' 2 primary 'Borgstahl, G.E.O.' 3 primary 'Masson, P.' 4 primary 'Lockridge, O.' 5 1 'Nachon, F.' 6 1 'Nicolet, Y.' 7 1 'Viguie, N.' 8 1 'Masson, P.' 9 1 'Fontecilla-Camps, J.C.' 10 1 'Lockridge, O.' 11 2 'Nicolet, Y.' 12 2 'Lockridge, O.' 13 2 'Masson, P.' 14 2 'Fontecilla-Camps, J.C.' 15 2 'Nachon, F.' 16 # _cell.entry_id 1XLU _cell.length_a 154.495 _cell.length_b 154.495 _cell.length_c 127.290 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 16 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 1XLU _symmetry.space_group_name_H-M 'I 4 2 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 97 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man BUTYRYLCHOLINESTERASE 59745.574 1 3.1.1.8 aged ? 'aged, Ser 198 covalently bound to ISP' 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 7 ? ? ? ? 3 non-polymer man BETA-L-FUCOSE 164.156 1 ? ? ? ? 4 non-polymer syn 'SULFATE ION' 96.063 3 ? ? ? ? 5 non-polymer syn 'CHLORIDE ION' 35.453 2 ? ? ? ? 6 non-polymer syn PHOSPHORYLISOPROPANE 140.075 1 ? ? ? ? 7 non-polymer syn GLYCEROL 92.094 4 ? ? ? ? 8 water nat water 18.015 255 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Acylcholine acylhydrolase; Choline esterase II; Butyrylcholine esterase; Pseudocholinesterase' # _entity_name_sys.entity_id 1 _entity_name_sys.name E.C.3.1.1.8 # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer yes _entity_poly.pdbx_seq_one_letter_code ;EDDIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSC(CSS)QNIDQSFPGF HGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLAL PGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSL YEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQ ILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDY NFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAK YGNPQETQNQSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV ; _entity_poly.pdbx_seq_one_letter_code_can ;EDDIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSE MWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNP EAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEAR NRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVG VNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFIC PALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNP QETQNQSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLU n 1 2 ASP n 1 3 ASP n 1 4 ILE n 1 5 ILE n 1 6 ILE n 1 7 ALA n 1 8 THR n 1 9 LYS n 1 10 ASN n 1 11 GLY n 1 12 LYS n 1 13 VAL n 1 14 ARG n 1 15 GLY n 1 16 MET n 1 17 GLN n 1 18 LEU n 1 19 THR n 1 20 VAL n 1 21 PHE n 1 22 GLY n 1 23 GLY n 1 24 THR n 1 25 VAL n 1 26 THR n 1 27 ALA n 1 28 PHE n 1 29 LEU n 1 30 GLY n 1 31 ILE n 1 32 PRO n 1 33 TYR n 1 34 ALA n 1 35 GLN n 1 36 PRO n 1 37 PRO n 1 38 LEU n 1 39 GLY n 1 40 ARG n 1 41 LEU n 1 42 ARG n 1 43 PHE n 1 44 LYS n 1 45 LYS n 1 46 PRO n 1 47 GLN n 1 48 SER n 1 49 LEU n 1 50 THR n 1 51 LYS n 1 52 TRP n 1 53 SER n 1 54 ASP n 1 55 ILE n 1 56 TRP n 1 57 ASN n 1 58 ALA n 1 59 THR n 1 60 LYS n 1 61 TYR n 1 62 ALA n 1 63 ASN n 1 64 SER n 1 65 CYS n 1 66 CSS n 1 67 GLN n 1 68 ASN n 1 69 ILE n 1 70 ASP n 1 71 GLN n 1 72 SER n 1 73 PHE n 1 74 PRO n 1 75 GLY n 1 76 PHE n 1 77 HIS n 1 78 GLY n 1 79 SER n 1 80 GLU n 1 81 MET n 1 82 TRP n 1 83 ASN n 1 84 PRO n 1 85 ASN n 1 86 THR n 1 87 ASP n 1 88 LEU n 1 89 SER n 1 90 GLU n 1 91 ASP n 1 92 CYS n 1 93 LEU n 1 94 TYR n 1 95 LEU n 1 96 ASN n 1 97 VAL n 1 98 TRP n 1 99 ILE n 1 100 PRO n 1 101 ALA n 1 102 PRO n 1 103 LYS n 1 104 PRO n 1 105 LYS n 1 106 ASN n 1 107 ALA n 1 108 THR n 1 109 VAL n 1 110 LEU n 1 111 ILE n 1 112 TRP n 1 113 ILE n 1 114 TYR n 1 115 GLY n 1 116 GLY n 1 117 GLY n 1 118 PHE n 1 119 GLN n 1 120 THR n 1 121 GLY n 1 122 THR n 1 123 SER n 1 124 SER n 1 125 LEU n 1 126 HIS n 1 127 VAL n 1 128 TYR n 1 129 ASP n 1 130 GLY n 1 131 LYS n 1 132 PHE n 1 133 LEU n 1 134 ALA n 1 135 ARG n 1 136 VAL n 1 137 GLU n 1 138 ARG n 1 139 VAL n 1 140 ILE n 1 141 VAL n 1 142 VAL n 1 143 SER n 1 144 MET n 1 145 ASN n 1 146 TYR n 1 147 ARG n 1 148 VAL n 1 149 GLY n 1 150 ALA n 1 151 LEU n 1 152 GLY n 1 153 PHE n 1 154 LEU n 1 155 ALA n 1 156 LEU n 1 157 PRO n 1 158 GLY n 1 159 ASN n 1 160 PRO n 1 161 GLU n 1 162 ALA n 1 163 PRO n 1 164 GLY n 1 165 ASN n 1 166 MET n 1 167 GLY n 1 168 LEU n 1 169 PHE n 1 170 ASP n 1 171 GLN n 1 172 GLN n 1 173 LEU n 1 174 ALA n 1 175 LEU n 1 176 GLN n 1 177 TRP n 1 178 VAL n 1 179 GLN n 1 180 LYS n 1 181 ASN n 1 182 ILE n 1 183 ALA n 1 184 ALA n 1 185 PHE n 1 186 GLY n 1 187 GLY n 1 188 ASN n 1 189 PRO n 1 190 LYS n 1 191 SER n 1 192 VAL n 1 193 THR n 1 194 LEU n 1 195 PHE n 1 196 GLY n 1 197 GLU n 1 198 SER n 1 199 ALA n 1 200 GLY n 1 201 ALA n 1 202 ALA n 1 203 SER n 1 204 VAL n 1 205 SER n 1 206 LEU n 1 207 HIS n 1 208 LEU n 1 209 LEU n 1 210 SER n 1 211 PRO n 1 212 GLY n 1 213 SER n 1 214 HIS n 1 215 SER n 1 216 LEU n 1 217 PHE n 1 218 THR n 1 219 ARG n 1 220 ALA n 1 221 ILE n 1 222 LEU n 1 223 GLN n 1 224 SER n 1 225 GLY n 1 226 SER n 1 227 PHE n 1 228 ASN n 1 229 ALA n 1 230 PRO n 1 231 TRP n 1 232 ALA n 1 233 VAL n 1 234 THR n 1 235 SER n 1 236 LEU n 1 237 TYR n 1 238 GLU n 1 239 ALA n 1 240 ARG n 1 241 ASN n 1 242 ARG n 1 243 THR n 1 244 LEU n 1 245 ASN n 1 246 LEU n 1 247 ALA n 1 248 LYS n 1 249 LEU n 1 250 THR n 1 251 GLY n 1 252 CYS n 1 253 SER n 1 254 ARG n 1 255 GLU n 1 256 ASN n 1 257 GLU n 1 258 THR n 1 259 GLU n 1 260 ILE n 1 261 ILE n 1 262 LYS n 1 263 CYS n 1 264 LEU n 1 265 ARG n 1 266 ASN n 1 267 LYS n 1 268 ASP n 1 269 PRO n 1 270 GLN n 1 271 GLU n 1 272 ILE n 1 273 LEU n 1 274 LEU n 1 275 ASN n 1 276 GLU n 1 277 ALA n 1 278 PHE n 1 279 VAL n 1 280 VAL n 1 281 PRO n 1 282 TYR n 1 283 GLY n 1 284 THR n 1 285 PRO n 1 286 LEU n 1 287 SER n 1 288 VAL n 1 289 ASN n 1 290 PHE n 1 291 GLY n 1 292 PRO n 1 293 THR n 1 294 VAL n 1 295 ASP n 1 296 GLY n 1 297 ASP n 1 298 PHE n 1 299 LEU n 1 300 THR n 1 301 ASP n 1 302 MET n 1 303 PRO n 1 304 ASP n 1 305 ILE n 1 306 LEU n 1 307 LEU n 1 308 GLU n 1 309 LEU n 1 310 GLY n 1 311 GLN n 1 312 PHE n 1 313 LYS n 1 314 LYS n 1 315 THR n 1 316 GLN n 1 317 ILE n 1 318 LEU n 1 319 VAL n 1 320 GLY n 1 321 VAL n 1 322 ASN n 1 323 LYS n 1 324 ASP n 1 325 GLU n 1 326 GLY n 1 327 THR n 1 328 ALA n 1 329 PHE n 1 330 LEU n 1 331 VAL n 1 332 TYR n 1 333 GLY n 1 334 ALA n 1 335 PRO n 1 336 GLY n 1 337 PHE n 1 338 SER n 1 339 LYS n 1 340 ASP n 1 341 ASN n 1 342 ASN n 1 343 SER n 1 344 ILE n 1 345 ILE n 1 346 THR n 1 347 ARG n 1 348 LYS n 1 349 GLU n 1 350 PHE n 1 351 GLN n 1 352 GLU n 1 353 GLY n 1 354 LEU n 1 355 LYS n 1 356 ILE n 1 357 PHE n 1 358 PHE n 1 359 PRO n 1 360 GLY n 1 361 VAL n 1 362 SER n 1 363 GLU n 1 364 PHE n 1 365 GLY n 1 366 LYS n 1 367 GLU n 1 368 SER n 1 369 ILE n 1 370 LEU n 1 371 PHE n 1 372 HIS n 1 373 TYR n 1 374 THR n 1 375 ASP n 1 376 TRP n 1 377 VAL n 1 378 ASP n 1 379 ASP n 1 380 GLN n 1 381 ARG n 1 382 PRO n 1 383 GLU n 1 384 ASN n 1 385 TYR n 1 386 ARG n 1 387 GLU n 1 388 ALA n 1 389 LEU n 1 390 GLY n 1 391 ASP n 1 392 VAL n 1 393 VAL n 1 394 GLY n 1 395 ASP n 1 396 TYR n 1 397 ASN n 1 398 PHE n 1 399 ILE n 1 400 CYS n 1 401 PRO n 1 402 ALA n 1 403 LEU n 1 404 GLU n 1 405 PHE n 1 406 THR n 1 407 LYS n 1 408 LYS n 1 409 PHE n 1 410 SER n 1 411 GLU n 1 412 TRP n 1 413 GLY n 1 414 ASN n 1 415 ASN n 1 416 ALA n 1 417 PHE n 1 418 PHE n 1 419 TYR n 1 420 TYR n 1 421 PHE n 1 422 GLU n 1 423 HIS n 1 424 ARG n 1 425 SER n 1 426 SER n 1 427 LYS n 1 428 LEU n 1 429 PRO n 1 430 TRP n 1 431 PRO n 1 432 GLU n 1 433 TRP n 1 434 MET n 1 435 GLY n 1 436 VAL n 1 437 MET n 1 438 HIS n 1 439 GLY n 1 440 TYR n 1 441 GLU n 1 442 ILE n 1 443 GLU n 1 444 PHE n 1 445 VAL n 1 446 PHE n 1 447 GLY n 1 448 LEU n 1 449 PRO n 1 450 LEU n 1 451 GLU n 1 452 ARG n 1 453 ARG n 1 454 ASP n 1 455 GLN n 1 456 TYR n 1 457 THR n 1 458 LYS n 1 459 ALA n 1 460 GLU n 1 461 GLU n 1 462 ILE n 1 463 LEU n 1 464 SER n 1 465 ARG n 1 466 SER n 1 467 ILE n 1 468 VAL n 1 469 LYS n 1 470 ARG n 1 471 TRP n 1 472 ALA n 1 473 ASN n 1 474 PHE n 1 475 ALA n 1 476 LYS n 1 477 TYR n 1 478 GLY n 1 479 ASN n 1 480 PRO n 1 481 GLN n 1 482 GLU n 1 483 THR n 1 484 GLN n 1 485 ASN n 1 486 GLN n 1 487 SER n 1 488 THR n 1 489 SER n 1 490 TRP n 1 491 PRO n 1 492 VAL n 1 493 PHE n 1 494 LYS n 1 495 SER n 1 496 THR n 1 497 GLU n 1 498 GLN n 1 499 LYS n 1 500 TYR n 1 501 LEU n 1 502 THR n 1 503 LEU n 1 504 ASN n 1 505 THR n 1 506 GLU n 1 507 SER n 1 508 THR n 1 509 ARG n 1 510 ILE n 1 511 MET n 1 512 THR n 1 513 LYS n 1 514 LEU n 1 515 ARG n 1 516 ALA n 1 517 GLN n 1 518 GLN n 1 519 CYS n 1 520 ARG n 1 521 PHE n 1 522 TRP n 1 523 THR n 1 524 SER n 1 525 PHE n 1 526 PHE n 1 527 PRO n 1 528 LYS n 1 529 VAL n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus Homo _entity_src_gen.pdbx_gene_src_gene ? _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'Chinese hamster' _entity_src_gen.pdbx_host_org_scientific_name 'Cricetulus griseus' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 10029 _entity_src_gen.host_org_genus Cricetulus _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell 'Baby Hampster Kidney Cells' _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type Plasmid _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name PGS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.entity_id 1 _struct_ref.db_name UNP _struct_ref.db_code CHLE_HUMAN _struct_ref.pdbx_db_accession P06276 _struct_ref.pdbx_align_begin 29 _struct_ref.pdbx_seq_one_letter_code ;EDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSE MWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNP EAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEAR NRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVG VNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFIC PALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNP NETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV ; _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 1XLU _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 529 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession P06276 _struct_ref_seq.db_align_beg 29 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 557 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 1 _struct_ref_seq.pdbx_auth_seq_align_end 529 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 1XLU GLN A 17 ? UNP P06276 ASN 45 ENGINEERED 17 1 1 1XLU GLN A 455 ? UNP P06276 ASN 483 ENGINEERED 455 2 1 1XLU GLN A 481 ? UNP P06276 ASN 509 ENGINEERED 481 3 1 1XLU GLN A 486 ? UNP P06276 ASN 514 ENGINEERED 486 4 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CL non-polymer . 'CHLORIDE ION' ? 'Cl -1' 35.453 CSS 'L-peptide linking' n S-MERCAPTOCYSTEINE ? 'C3 H7 N O2 S2' 153.223 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FUL L-saccharide . BETA-L-FUCOSE 6-DEOXY-BETA-L-GALACTOSE 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 ISP non-polymer . PHOSPHORYLISOPROPANE ? 'C3 H9 O4 P' 140.075 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 1XLU _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_percent_sol 56 _exptl_crystal.density_Matthews 2.9 _exptl_crystal.density_meas ? _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 298 _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_details 'AMMONIUM SULFATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K' _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100. _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector 'IMAGE PLATE' _diffrn_detector.type 'RIGAKU RAXIS IV' _diffrn_detector.pdbx_collection_date 2003-12-15 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.5418 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source 'ROTATING ANODE' _diffrn_source.type 'RIGAKU FR-E SUPERBRIGHT' _diffrn_source.pdbx_synchrotron_site ? _diffrn_source.pdbx_synchrotron_beamline ? _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.5418 # _reflns.entry_id 1XLU _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.d_resolution_high 2.198 _reflns.d_resolution_low 50. _reflns.number_all ? _reflns.number_obs 37851 _reflns.percent_possible_obs 96.3 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value 0.063 _reflns.pdbx_netI_over_sigmaI 27.9 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 7.8 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 2.198 _reflns_shell.d_res_low 2.28 _reflns_shell.percent_possible_all 100. _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value 0.401 _reflns_shell.meanI_over_sigI_obs 4.6 _reflns_shell.pdbx_redundancy 7.7 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 1XLU _refine.ls_number_reflns_obs 33683 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 40.00 _refine.ls_d_res_high 2.198 _refine.ls_percent_reflns_obs 90.27 _refine.ls_R_factor_obs 0.19551 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.19305 _refine.ls_R_factor_R_free 0.24216 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.1 _refine.ls_number_reflns_R_free 1806 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.942 _refine.correlation_coeff_Fo_to_Fc_free 0.920 _refine.B_iso_mean 45.803 _refine.aniso_B[1][1] -1.30 _refine.aniso_B[2][2] -1.30 _refine.aniso_B[3][3] 2.59 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ? _refine.pdbx_starting_model 1POI _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.250 _refine.pdbx_overall_ESU_R_Free 0.209 _refine.overall_SU_ML 0.124 _refine.overall_SU_B 4.843 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 4180 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 156 _refine_hist.number_atoms_solvent 255 _refine_hist.number_atoms_total 4591 _refine_hist.d_res_high 2.198 _refine_hist.d_res_low 40.00 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.017 0.022 ? 4563 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.600 1.963 ? 6212 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.350 5.000 ? 542 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 36.928 24.019 ? 209 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 17.094 15.000 ? 717 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 14.606 15.000 ? 23 'X-RAY DIFFRACTION' ? r_chiral_restr 0.109 0.200 ? 665 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.007 0.020 ? 3471 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined 0.215 0.200 ? 2263 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined 0.315 0.200 ? 3100 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 0.158 0.200 ? 333 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 0.214 0.200 ? 47 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 0.184 0.200 ? 12 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 1.235 1.500 ? 2742 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 1.702 2.000 ? 4317 'X-RAY DIFFRACTION' ? r_scbond_it 2.654 3.000 ? 2090 'X-RAY DIFFRACTION' ? r_scangle_it 3.831 4.500 ? 1895 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.198 _refine_ls_shell.d_res_low 2.255 _refine_ls_shell.number_reflns_R_work 2396 _refine_ls_shell.R_factor_R_work 0.211 _refine_ls_shell.percent_reflns_obs 89.04 _refine_ls_shell.R_factor_R_free 0.25 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 154 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 1XLU _struct.title 'X-Ray Structure Of Di-Isopropyl-Phosphoro-Fluoridate (Dfp) Inhibited Butyrylcholinesterase after Aging' _struct.pdbx_descriptor 'BUTYRYLCHOLINESTERASE (E.C.3.1.1.8)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 1XLU _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'CHOLINESTERASE, HYDROLASE' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 3 ? E N N 2 ? F N N 2 ? G N N 2 ? H N N 2 ? I N N 2 ? J N N 4 ? K N N 4 ? L N N 4 ? M N N 5 ? N N N 5 ? O N N 6 ? P N N 7 ? Q N N 7 ? R N N 7 ? S N N 7 ? T N N 8 ? # _struct_biol.id 1 _struct_biol.pdbx_parent_biol_id ? _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 LEU A 38 ? ARG A 42 ? LEU A 38 ARG A 42 5 ? 5 HELX_P HELX_P2 2 PHE A 76 ? MET A 81 ? PHE A 76 MET A 81 1 ? 6 HELX_P HELX_P3 3 LEU A 125 ? ASP A 129 ? LEU A 125 ASP A 129 5 ? 5 HELX_P HELX_P4 4 GLY A 130 ? ARG A 138 ? GLY A 130 ARG A 138 1 ? 9 HELX_P HELX_P5 5 GLY A 149 ? LEU A 154 ? GLY A 149 LEU A 154 1 ? 6 HELX_P HELX_P6 6 ASN A 165 ? ILE A 182 ? ASN A 165 ILE A 182 1 ? 18 HELX_P HELX_P7 7 ALA A 183 ? PHE A 185 ? ALA A 183 PHE A 185 5 ? 3 HELX_P HELX_P8 8 SER A 198 ? SER A 210 ? SER A 198 SER A 210 1 ? 13 HELX_P HELX_P9 9 PRO A 211 ? PHE A 217 ? PRO A 211 PHE A 217 5 ? 7 HELX_P HELX_P10 10 SER A 235 ? THR A 250 ? SER A 235 THR A 250 1 ? 16 HELX_P HELX_P11 11 ASN A 256 ? ARG A 265 ? ASN A 256 ARG A 265 1 ? 10 HELX_P HELX_P12 12 ASP A 268 ? ALA A 277 ? ASP A 268 ALA A 277 1 ? 10 HELX_P HELX_P13 13 PHE A 278 ? VAL A 280 ? PHE A 278 VAL A 280 5 ? 3 HELX_P HELX_P14 14 MET A 302 ? LEU A 309 ? MET A 302 LEU A 309 1 ? 8 HELX_P HELX_P15 15 GLY A 326 ? VAL A 331 ? GLY A 326 VAL A 331 1 ? 6 HELX_P HELX_P16 16 THR A 346 ? PHE A 358 ? THR A 346 PHE A 358 1 ? 13 HELX_P HELX_P17 17 SER A 362 ? THR A 374 ? SER A 362 THR A 374 1 ? 13 HELX_P HELX_P18 18 GLU A 383 ? PHE A 398 ? GLU A 383 PHE A 398 1 ? 16 HELX_P HELX_P19 19 PHE A 398 ? GLU A 411 ? PHE A 398 GLU A 411 1 ? 14 HELX_P HELX_P20 20 PRO A 431 ? GLY A 435 ? PRO A 431 GLY A 435 5 ? 5 HELX_P HELX_P21 21 GLU A 441 ? PHE A 446 ? GLU A 441 PHE A 446 1 ? 6 HELX_P HELX_P22 22 GLY A 447 ? GLN A 455 ? GLY A 447 GLN A 455 5 ? 9 HELX_P HELX_P23 23 THR A 457 ? GLY A 478 ? THR A 457 GLY A 478 1 ? 22 HELX_P HELX_P24 24 ARG A 515 ? SER A 524 ? ARG A 515 SER A 524 1 ? 10 HELX_P HELX_P25 25 PHE A 525 ? VAL A 529 ? PHE A 525 VAL A 529 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 65 SG ? ? ? 1_555 A CYS 92 SG ? ? A CYS 65 A CYS 92 1_555 ? ? ? ? ? ? ? 2.066 ? disulf2 disulf ? ? A CYS 252 SG ? ? ? 1_555 A CYS 263 SG ? ? A CYS 252 A CYS 263 1_555 ? ? ? ? ? ? ? 2.087 ? disulf3 disulf ? ? A CYS 400 SG ? ? ? 1_555 A CYS 519 SG ? ? A CYS 400 A CYS 519 1_555 ? ? ? ? ? ? ? 2.067 ? covale1 covale ? ? A CYS 65 C ? ? ? 1_555 A CSS 66 N ? ? A CYS 65 A CSS 66 1_555 ? ? ? ? ? ? ? 1.337 ? covale2 covale ? ? A CSS 66 C ? ? ? 1_555 A GLN 67 N ? ? A CSS 66 A GLN 67 1_555 ? ? ? ? ? ? ? 1.314 ? covale3 covale ? ? A ASN 57 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 57 A NAG 536 1_555 ? ? ? ? ? ? ? 1.458 ? covale4 covale ? ? A ASN 106 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 106 A NAG 535 1_555 ? ? ? ? ? ? ? 1.425 ? covale5 covale ? ? A ASN 241 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 241 A NAG 530 1_555 ? ? ? ? ? ? ? 1.451 ? covale6 covale ? ? A ASN 341 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 341 A NAG 533 1_555 ? ? ? ? ? ? ? 1.422 ? covale7 covale ? ? A ASN 485 ND2 ? ? ? 1_555 I NAG . C1 ? ? A ASN 485 A NAG 537 1_555 ? ? ? ? ? ? ? 1.449 ? covale8 covale ? ? B NAG . O4 ? ? ? 1_555 C NAG . C1 ? ? A NAG 530 A NAG 531 1_555 ? ? ? ? ? ? ? 1.447 ? covale9 covale ? ? B NAG . O6 ? ? ? 1_555 D FUL . C1 ? ? A NAG 530 A FUL 532 1_555 ? ? ? ? ? ? ? 1.440 ? covale10 covale ? ? E NAG . O4 ? ? ? 1_555 F NAG . C1 ? ? A NAG 533 A NAG 534 1_555 ? ? ? ? ? ? ? 1.435 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # _struct_mon_prot_cis.pdbx_id 1 _struct_mon_prot_cis.label_comp_id ALA _struct_mon_prot_cis.label_seq_id 101 _struct_mon_prot_cis.label_asym_id A _struct_mon_prot_cis.label_alt_id . _struct_mon_prot_cis.pdbx_PDB_ins_code ? _struct_mon_prot_cis.auth_comp_id ALA _struct_mon_prot_cis.auth_seq_id 101 _struct_mon_prot_cis.auth_asym_id A _struct_mon_prot_cis.pdbx_label_comp_id_2 PRO _struct_mon_prot_cis.pdbx_label_seq_id_2 102 _struct_mon_prot_cis.pdbx_label_asym_id_2 A _struct_mon_prot_cis.pdbx_PDB_ins_code_2 ? _struct_mon_prot_cis.pdbx_auth_comp_id_2 PRO _struct_mon_prot_cis.pdbx_auth_seq_id_2 102 _struct_mon_prot_cis.pdbx_auth_asym_id_2 A _struct_mon_prot_cis.pdbx_PDB_model_num 1 _struct_mon_prot_cis.pdbx_omega_angle 2.42 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 3 ? B ? 11 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? parallel B 5 6 ? parallel B 6 7 ? parallel B 7 8 ? parallel B 8 9 ? parallel B 9 10 ? parallel B 10 11 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 ILE A 5 ? THR A 8 ? ILE A 5 THR A 8 A 2 GLY A 11 ? ARG A 14 ? GLY A 11 ARG A 14 A 3 ILE A 55 ? ASN A 57 ? ILE A 55 ASN A 57 B 1 MET A 16 ? VAL A 20 ? MET A 16 VAL A 20 B 2 GLY A 23 ? PRO A 32 ? GLY A 23 PRO A 32 B 3 TYR A 94 ? ALA A 101 ? TYR A 94 ALA A 101 B 4 ILE A 140 ? MET A 144 ? ILE A 140 MET A 144 B 5 ALA A 107 ? ILE A 113 ? ALA A 107 ILE A 113 B 6 GLY A 187 ? GLU A 197 ? GLY A 187 GLU A 197 B 7 ARG A 219 ? GLN A 223 ? ARG A 219 GLN A 223 B 8 ILE A 317 ? ASN A 322 ? ILE A 317 ASN A 322 B 9 ALA A 416 ? PHE A 421 ? ALA A 416 PHE A 421 B 10 LYS A 499 ? LEU A 503 ? LYS A 499 LEU A 503 B 11 ILE A 510 ? THR A 512 ? ILE A 510 THR A 512 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N THR A 8 ? N THR A 8 O GLY A 11 ? O GLY A 11 A 2 3 N ARG A 14 ? N ARG A 14 O TRP A 56 ? O TRP A 56 B 1 2 N LEU A 18 ? N LEU A 18 O VAL A 25 ? O VAL A 25 B 2 3 N ILE A 31 ? N ILE A 31 O LEU A 95 ? O LEU A 95 B 3 4 N TRP A 98 ? N TRP A 98 O VAL A 141 ? O VAL A 141 B 4 5 O VAL A 142 ? O VAL A 142 N TRP A 112 ? N TRP A 112 B 5 6 N VAL A 109 ? N VAL A 109 O SER A 191 ? O SER A 191 B 6 7 N GLY A 196 ? N GLY A 196 O GLN A 223 ? O GLN A 223 B 7 8 N LEU A 222 ? N LEU A 222 O LEU A 318 ? O LEU A 318 B 8 9 N VAL A 319 ? N VAL A 319 O PHE A 417 ? O PHE A 417 B 9 10 N TYR A 420 ? N TYR A 420 O LEU A 503 ? O LEU A 503 B 10 11 N TYR A 500 ? N TYR A 500 O MET A 511 ? O MET A 511 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A 530' AC2 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 531' AC3 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE FUL A 532' AC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 533' AC5 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 534' AC6 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 535' AC7 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 536' AC8 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 537' AC9 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE SO4 A 601' BC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE SO4 A 602' BC2 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE SO4 A 603' BC3 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE CL A 701' BC4 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE CL A 702' BC5 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE ISP A 1001' BC6 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE GOL A 604' BC7 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 605' BC8 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 606' BC9 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE GOL A 607' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 6 TYR A 237 ? TYR A 237 . ? 1_555 ? 2 AC1 6 ASN A 241 ? ASN A 241 . ? 1_555 ? 3 AC1 6 ASN A 245 ? ASN A 245 . ? 1_555 ? 4 AC1 6 PRO A 281 ? PRO A 281 . ? 1_555 ? 5 AC1 6 NAG C . ? NAG A 531 . ? 1_555 ? 6 AC1 6 FUL D . ? FUL A 532 . ? 1_555 ? 7 AC2 2 NAG B . ? NAG A 530 . ? 1_555 ? 8 AC2 2 FUL D . ? FUL A 532 . ? 1_555 ? 9 AC3 7 ASN A 245 ? ASN A 245 . ? 1_555 ? 10 AC3 7 LEU A 249 ? LEU A 249 . ? 1_555 ? 11 AC3 7 PHE A 278 ? PHE A 278 . ? 1_555 ? 12 AC3 7 NAG B . ? NAG A 530 . ? 1_555 ? 13 AC3 7 NAG C . ? NAG A 531 . ? 1_555 ? 14 AC3 7 HOH T . ? HOH A 1192 . ? 1_555 ? 15 AC3 7 HOH T . ? HOH A 1333 . ? 1_555 ? 16 AC4 5 SER A 338 ? SER A 338 . ? 1_555 ? 17 AC4 5 ASN A 341 ? ASN A 341 . ? 1_555 ? 18 AC4 5 ASN A 342 ? ASN A 342 . ? 1_555 ? 19 AC4 5 NAG F . ? NAG A 534 . ? 1_555 ? 20 AC4 5 HOH T . ? HOH A 1346 . ? 1_555 ? 21 AC5 2 GLY A 336 ? GLY A 336 . ? 1_555 ? 22 AC5 2 NAG E . ? NAG A 533 . ? 1_555 ? 23 AC6 2 ASN A 106 ? ASN A 106 . ? 1_555 ? 24 AC6 2 ASN A 188 ? ASN A 188 . ? 1_555 ? 25 AC7 2 ARG A 14 ? ARG A 14 . ? 1_555 ? 26 AC7 2 ASN A 57 ? ASN A 57 . ? 1_555 ? 27 AC8 2 ARG A 465 ? ARG A 465 . ? 1_555 ? 28 AC8 2 ASN A 485 ? ASN A 485 . ? 1_555 ? 29 AC9 4 GLN A 316 ? GLN A 316 . ? 1_555 ? 30 AC9 4 GLY A 413 ? GLY A 413 . ? 1_555 ? 31 AC9 4 ASN A 414 ? ASN A 414 . ? 1_555 ? 32 AC9 4 ASN A 415 ? ASN A 415 . ? 1_555 ? 33 BC1 4 HIS A 372 ? HIS A 372 . ? 1_555 ? 34 BC1 4 ARG A 520 ? ARG A 520 . ? 1_555 ? 35 BC1 4 PHE A 521 ? PHE A 521 . ? 1_555 ? 36 BC1 4 LYS A 528 ? LYS A 528 . ? 5_655 ? 37 BC2 2 ARG A 347 ? ARG A 347 . ? 1_555 ? 38 BC2 2 GLN A 351 ? GLN A 351 . ? 1_555 ? 39 BC3 1 THR A 508 ? THR A 508 . ? 1_555 ? 40 BC4 2 TYR A 420 ? TYR A 420 . ? 1_555 ? 41 BC4 2 HOH T . ? HOH A 1329 . ? 1_555 ? 42 BC5 7 GLY A 115 ? GLY A 115 . ? 1_555 ? 43 BC5 7 GLY A 116 ? GLY A 116 . ? 1_555 ? 44 BC5 7 GLY A 117 ? GLY A 117 . ? 1_555 ? 45 BC5 7 SER A 198 ? SER A 198 . ? 1_555 ? 46 BC5 7 ALA A 199 ? ALA A 199 . ? 1_555 ? 47 BC5 7 HIS A 438 ? HIS A 438 . ? 1_555 ? 48 BC5 7 GOL Q . ? GOL A 605 . ? 1_555 ? 49 BC6 6 TRP A 231 ? TRP A 231 . ? 1_555 ? 50 BC6 6 THR A 234 ? THR A 234 . ? 1_555 ? 51 BC6 6 GLU A 238 ? GLU A 238 . ? 1_555 ? 52 BC6 6 ARG A 242 ? ARG A 242 . ? 1_555 ? 53 BC6 6 VAL A 288 ? VAL A 288 . ? 1_555 ? 54 BC6 6 HOH T . ? HOH A 1314 . ? 1_555 ? 55 BC7 5 TRP A 82 ? TRP A 82 . ? 1_555 ? 56 BC7 5 GLY A 115 ? GLY A 115 . ? 1_555 ? 57 BC7 5 GLY A 116 ? GLY A 116 . ? 1_555 ? 58 BC7 5 GLU A 197 ? GLU A 197 . ? 1_555 ? 59 BC7 5 ISP O . ? ISP A 1001 . ? 1_555 ? 60 BC8 5 LEU A 18 ? LEU A 18 . ? 1_555 ? 61 BC8 5 TYR A 61 ? TYR A 61 . ? 1_555 ? 62 BC8 5 TRP A 98 ? TRP A 98 . ? 1_555 ? 63 BC8 5 ASP A 129 ? ASP A 129 . ? 1_555 ? 64 BC8 5 LYS A 131 ? LYS A 131 . ? 1_555 ? 65 BC9 8 MET A 81 ? MET A 81 . ? 1_555 ? 66 BC9 8 SER A 425 ? SER A 425 . ? 1_555 ? 67 BC9 8 LYS A 427 ? LYS A 427 . ? 1_555 ? 68 BC9 8 LEU A 428 ? LEU A 428 . ? 1_555 ? 69 BC9 8 TYR A 440 ? TYR A 440 . ? 1_555 ? 70 BC9 8 GLU A 443 ? GLU A 443 . ? 1_555 ? 71 BC9 8 HOH T . ? HOH A 1198 . ? 1_555 ? 72 BC9 8 HOH T . ? HOH A 1299 . ? 1_555 ? # _atom_sites.entry_id 1XLU _atom_sites.fract_transf_matrix[1][1] 0.006473 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.006473 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007856 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CL N O P S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ILE A 1 4 ? 42.747 95.960 48.879 1.00 64.08 ? 4 ILE A N 1 ATOM 2 C CA . ILE A 1 4 ? 43.857 95.030 48.482 1.00 64.26 ? 4 ILE A CA 1 ATOM 3 C C . ILE A 1 4 ? 45.214 95.600 48.894 1.00 63.37 ? 4 ILE A C 1 ATOM 4 O O . ILE A 1 4 ? 45.601 96.686 48.454 1.00 63.80 ? 4 ILE A O 1 ATOM 5 C CB . ILE A 1 4 ? 43.839 94.754 46.958 1.00 64.83 ? 4 ILE A CB 1 ATOM 6 C CG1 . ILE A 1 4 ? 42.439 94.997 46.359 1.00 65.91 ? 4 ILE A CG1 1 ATOM 7 C CG2 . ILE A 1 4 ? 44.392 93.351 46.657 1.00 65.57 ? 4 ILE A CG2 1 ATOM 8 C CD1 . ILE A 1 4 ? 42.046 96.516 46.199 1.00 67.17 ? 4 ILE A CD1 1 ATOM 9 N N . ILE A 1 5 ? 45.922 94.866 49.749 1.00 61.95 ? 5 ILE A N 1 ATOM 10 C CA . ILE A 1 5 ? 47.177 95.319 50.321 1.00 60.49 ? 5 ILE A CA 1 ATOM 11 C C . ILE A 1 5 ? 48.276 94.347 49.905 1.00 59.64 ? 5 ILE A C 1 ATOM 12 O O . ILE A 1 5 ? 48.062 93.139 49.873 1.00 59.29 ? 5 ILE A O 1 ATOM 13 C CB . ILE A 1 5 ? 47.075 95.411 51.880 1.00 60.58 ? 5 ILE A CB 1 ATOM 14 C CG1 . ILE A 1 5 ? 46.131 96.544 52.312 1.00 61.42 ? 5 ILE A CG1 1 ATOM 15 C CG2 . ILE A 1 5 ? 48.422 95.655 52.513 1.00 59.05 ? 5 ILE A CG2 1 ATOM 16 C CD1 . ILE A 1 5 ? 44.810 96.060 52.872 1.00 62.57 ? 5 ILE A CD1 1 ATOM 17 N N . ILE A 1 6 ? 49.446 94.882 49.579 1.00 58.33 ? 6 ILE A N 1 ATOM 18 C CA . ILE A 1 6 ? 50.557 94.068 49.131 1.00 57.20 ? 6 ILE A CA 1 ATOM 19 C C . ILE A 1 6 ? 51.714 94.430 50.011 1.00 57.19 ? 6 ILE A C 1 ATOM 20 O O . ILE A 1 6 ? 51.914 95.605 50.274 1.00 57.22 ? 6 ILE A O 1 ATOM 21 C CB . ILE A 1 6 ? 50.908 94.394 47.638 1.00 56.47 ? 6 ILE A CB 1 ATOM 22 C CG1 . ILE A 1 6 ? 49.741 94.083 46.704 1.00 55.81 ? 6 ILE A CG1 1 ATOM 23 C CG2 . ILE A 1 6 ? 52.170 93.666 47.196 1.00 56.21 ? 6 ILE A CG2 1 ATOM 24 C CD1 . ILE A 1 6 ? 49.413 92.590 46.490 1.00 53.90 ? 6 ILE A CD1 1 ATOM 25 N N . ALA A 1 7 ? 52.482 93.445 50.462 1.00 56.99 ? 7 ALA A N 1 ATOM 26 C CA . ALA A 1 7 ? 53.662 93.743 51.257 1.00 57.96 ? 7 ALA A CA 1 ATOM 27 C C . ALA A 1 7 ? 54.874 93.916 50.360 1.00 58.23 ? 7 ALA A C 1 ATOM 28 O O . ALA A 1 7 ? 55.156 93.055 49.545 1.00 58.95 ? 7 ALA A O 1 ATOM 29 C CB . ALA A 1 7 ? 53.915 92.646 52.303 1.00 58.21 ? 7 ALA A CB 1 ATOM 30 N N . THR A 1 8 ? 55.588 95.026 50.495 1.00 58.58 ? 8 THR A N 1 ATOM 31 C CA . THR A 1 8 ? 56.793 95.233 49.693 1.00 59.20 ? 8 THR A CA 1 ATOM 32 C C . THR A 1 8 ? 57.995 95.179 50.619 1.00 60.12 ? 8 THR A C 1 ATOM 33 O O . THR A 1 8 ? 57.822 95.127 51.840 1.00 60.86 ? 8 THR A O 1 ATOM 34 C CB . THR A 1 8 ? 56.747 96.576 48.882 1.00 58.92 ? 8 THR A CB 1 ATOM 35 O OG1 . THR A 1 8 ? 57.007 97.695 49.742 1.00 57.20 ? 8 THR A OG1 1 ATOM 36 C CG2 . THR A 1 8 ? 55.365 96.838 48.331 1.00 57.20 ? 8 THR A CG2 1 ATOM 37 N N . LYS A 1 9 ? 59.207 95.199 50.058 1.00 60.87 ? 9 LYS A N 1 ATOM 38 C CA . LYS A 1 9 ? 60.421 95.146 50.888 1.00 61.40 ? 9 LYS A CA 1 ATOM 39 C C . LYS A 1 9 ? 60.452 96.272 51.915 1.00 61.31 ? 9 LYS A C 1 ATOM 40 O O . LYS A 1 9 ? 60.955 96.078 53.019 1.00 61.01 ? 9 LYS A O 1 ATOM 41 C CB . LYS A 1 9 ? 61.713 95.158 50.041 1.00 61.76 ? 9 LYS A CB 1 ATOM 42 C CG . LYS A 1 9 ? 62.014 93.854 49.240 1.00 63.00 ? 9 LYS A CG 1 ATOM 43 C CD . LYS A 1 9 ? 62.033 92.599 50.094 1.00 64.23 ? 9 LYS A CD 1 ATOM 44 C CE . LYS A 1 9 ? 61.153 91.491 49.466 1.00 66.11 ? 9 LYS A CE 1 ATOM 45 N NZ . LYS A 1 9 ? 59.710 91.927 49.333 1.00 65.29 ? 9 LYS A NZ 1 ATOM 46 N N . ASN A 1 10 ? 59.893 97.431 51.539 1.00 61.32 ? 10 ASN A N 1 ATOM 47 C CA . ASN A 1 10 ? 59.868 98.659 52.366 1.00 61.34 ? 10 ASN A CA 1 ATOM 48 C C . ASN A 1 10 ? 58.596 98.907 53.155 1.00 60.72 ? 10 ASN A C 1 ATOM 49 O O . ASN A 1 10 ? 58.547 99.821 53.964 1.00 60.97 ? 10 ASN A O 1 ATOM 50 C CB . ASN A 1 10 ? 60.076 99.899 51.491 1.00 62.17 ? 10 ASN A CB 1 ATOM 51 C CG . ASN A 1 10 ? 61.524 100.147 51.172 1.00 64.45 ? 10 ASN A CG 1 ATOM 52 O OD1 . ASN A 1 10 ? 62.292 99.209 50.951 1.00 64.94 ? 10 ASN A OD1 1 ATOM 53 N ND2 . ASN A 1 10 ? 61.909 101.423 51.134 1.00 66.93 ? 10 ASN A ND2 1 ATOM 54 N N . GLY A 1 11 ? 57.545 98.146 52.899 1.00 59.66 ? 11 GLY A N 1 ATOM 55 C CA . GLY A 1 11 ? 56.343 98.342 53.661 1.00 58.64 ? 11 GLY A CA 1 ATOM 56 C C . GLY A 1 11 ? 55.142 97.908 52.874 1.00 58.70 ? 11 GLY A C 1 ATOM 57 O O . GLY A 1 11 ? 55.276 97.466 51.731 1.00 58.80 ? 11 GLY A O 1 ATOM 58 N N . LYS A 1 12 ? 53.973 98.039 53.493 1.00 57.69 ? 12 LYS A N 1 ATOM 59 C CA . LYS A 1 12 ? 52.713 97.679 52.877 1.00 57.58 ? 12 LYS A CA 1 ATOM 60 C C . LYS A 1 12 ? 52.171 98.832 52.057 1.00 56.63 ? 12 LYS A C 1 ATOM 61 O O . LYS A 1 12 ? 52.310 100.004 52.427 1.00 56.57 ? 12 LYS A O 1 ATOM 62 C CB . LYS A 1 12 ? 51.681 97.288 53.941 1.00 57.99 ? 12 LYS A CB 1 ATOM 63 C CG . LYS A 1 12 ? 52.077 96.107 54.784 1.00 61.03 ? 12 LYS A CG 1 ATOM 64 C CD . LYS A 1 12 ? 50.893 95.632 55.627 1.00 64.75 ? 12 LYS A CD 1 ATOM 65 C CE . LYS A 1 12 ? 51.144 94.235 56.185 1.00 65.96 ? 12 LYS A CE 1 ATOM 66 N NZ . LYS A 1 12 ? 49.947 93.747 56.933 1.00 68.66 ? 12 LYS A NZ 1 ATOM 67 N N . VAL A 1 13 ? 51.566 98.498 50.927 1.00 55.42 ? 13 VAL A N 1 ATOM 68 C CA . VAL A 1 13 ? 50.937 99.498 50.104 1.00 54.66 ? 13 VAL A CA 1 ATOM 69 C C . VAL A 1 13 ? 49.513 99.072 49.829 1.00 54.58 ? 13 VAL A C 1 ATOM 70 O O . VAL A 1 13 ? 49.233 97.897 49.637 1.00 54.64 ? 13 VAL A O 1 ATOM 71 C CB . VAL A 1 13 ? 51.749 99.820 48.776 1.00 54.78 ? 13 VAL A CB 1 ATOM 72 C CG1 . VAL A 1 13 ? 53.177 100.252 49.106 1.00 53.85 ? 13 VAL A CG1 1 ATOM 73 C CG2 . VAL A 1 13 ? 51.774 98.637 47.806 1.00 53.23 ? 13 VAL A CG2 1 ATOM 74 N N . ARG A 1 14 ? 48.609 100.042 49.824 1.00 55.18 ? 14 ARG A N 1 ATOM 75 C CA . ARG A 1 14 ? 47.208 99.807 49.478 1.00 55.25 ? 14 ARG A CA 1 ATOM 76 C C . ARG A 1 14 ? 46.908 100.368 48.080 1.00 54.49 ? 14 ARG A C 1 ATOM 77 O O . ARG A 1 14 ? 47.237 101.516 47.777 1.00 54.15 ? 14 ARG A O 1 ATOM 78 C CB . ARG A 1 14 ? 46.292 100.487 50.523 1.00 55.23 ? 14 ARG A CB 1 ATOM 79 C CG . ARG A 1 14 ? 44.794 100.542 50.152 1.00 56.78 ? 14 ARG A CG 1 ATOM 80 C CD . ARG A 1 14 ? 43.904 101.147 51.246 1.00 60.51 ? 14 ARG A CD 1 ATOM 81 N NE . ARG A 1 14 ? 43.679 100.193 52.333 1.00 62.64 ? 14 ARG A NE 1 ATOM 82 C CZ . ARG A 1 14 ? 44.143 100.312 53.577 1.00 63.46 ? 14 ARG A CZ 1 ATOM 83 N NH1 . ARG A 1 14 ? 44.875 101.367 53.933 1.00 62.46 ? 14 ARG A NH1 1 ATOM 84 N NH2 . ARG A 1 14 ? 43.865 99.357 54.470 1.00 64.09 ? 14 ARG A NH2 1 ATOM 85 N N . GLY A 1 15 ? 46.246 99.573 47.260 1.00 54.18 ? 15 GLY A N 1 ATOM 86 C CA . GLY A 1 15 ? 45.845 100.010 45.939 1.00 54.62 ? 15 GLY A CA 1 ATOM 87 C C . GLY A 1 15 ? 44.362 100.297 45.883 1.00 55.60 ? 15 GLY A C 1 ATOM 88 O O . GLY A 1 15 ? 43.681 100.395 46.924 1.00 56.13 ? 15 GLY A O 1 ATOM 89 N N . MET A 1 16 ? 43.866 100.469 44.671 1.00 55.16 ? 16 MET A N 1 ATOM 90 C CA . MET A 1 16 ? 42.472 100.677 44.438 1.00 55.70 ? 16 MET A CA 1 ATOM 91 C C . MET A 1 16 ? 41.996 99.804 43.277 1.00 55.81 ? 16 MET A C 1 ATOM 92 O O . MET A 1 16 ? 42.789 99.418 42.422 1.00 55.93 ? 16 MET A O 1 ATOM 93 C CB . MET A 1 16 ? 42.216 102.161 44.152 1.00 56.27 ? 16 MET A CB 1 ATOM 94 C CG . MET A 1 16 ? 42.652 102.679 42.789 1.00 58.17 ? 16 MET A CG 1 ATOM 95 S SD . MET A 1 16 ? 42.651 104.485 42.772 1.00 64.39 ? 16 MET A SD 1 ATOM 96 C CE . MET A 1 16 ? 40.882 104.809 42.611 1.00 65.81 ? 16 MET A CE 1 ATOM 97 N N . GLN A 1 17 ? 40.700 99.513 43.235 1.00 55.65 ? 17 GLN A N 1 ATOM 98 C CA . GLN A 1 17 ? 40.138 98.736 42.146 1.00 55.77 ? 17 GLN A CA 1 ATOM 99 C C . GLN A 1 17 ? 39.533 99.647 41.128 1.00 54.61 ? 17 GLN A C 1 ATOM 100 O O . GLN A 1 17 ? 38.991 100.690 41.467 1.00 54.69 ? 17 GLN A O 1 ATOM 101 C CB . GLN A 1 17 ? 39.079 97.779 42.665 1.00 56.85 ? 17 GLN A CB 1 ATOM 102 C CG . GLN A 1 17 ? 39.611 96.881 43.746 1.00 60.47 ? 17 GLN A CG 1 ATOM 103 C CD . GLN A 1 17 ? 39.838 95.457 43.283 1.00 64.81 ? 17 GLN A CD 1 ATOM 104 O OE1 . GLN A 1 17 ? 39.228 94.538 43.829 1.00 67.58 ? 17 GLN A OE1 1 ATOM 105 N NE2 . GLN A 1 17 ? 40.717 95.263 42.300 1.00 65.39 ? 17 GLN A NE2 1 ATOM 106 N N . LEU A 1 18 ? 39.645 99.243 39.872 1.00 53.83 ? 18 LEU A N 1 ATOM 107 C CA . LEU A 1 18 ? 39.144 100.015 38.743 1.00 53.42 ? 18 LEU A CA 1 ATOM 108 C C . LEU A 1 18 ? 38.373 99.078 37.857 1.00 52.80 ? 18 LEU A C 1 ATOM 109 O O . LEU A 1 18 ? 38.772 97.936 37.651 1.00 54.12 ? 18 LEU A O 1 ATOM 110 C CB . LEU A 1 18 ? 40.300 100.627 37.923 1.00 52.76 ? 18 LEU A CB 1 ATOM 111 C CG . LEU A 1 18 ? 41.392 101.453 38.602 1.00 52.37 ? 18 LEU A CG 1 ATOM 112 C CD1 . LEU A 1 18 ? 42.434 101.956 37.564 1.00 50.87 ? 18 LEU A CD1 1 ATOM 113 C CD2 . LEU A 1 18 ? 40.751 102.628 39.344 1.00 51.62 ? 18 LEU A CD2 1 ATOM 114 N N . THR A 1 19 ? 37.282 99.574 37.314 1.00 52.29 ? 19 THR A N 1 ATOM 115 C CA . THR A 1 19 ? 36.484 98.830 36.366 1.00 51.42 ? 19 THR A CA 1 ATOM 116 C C . THR A 1 19 ? 36.918 99.253 34.989 1.00 50.17 ? 19 THR A C 1 ATOM 117 O O . THR A 1 19 ? 36.997 100.441 34.693 1.00 48.10 ? 19 THR A O 1 ATOM 118 C CB . THR A 1 19 ? 34.978 99.147 36.596 1.00 52.19 ? 19 THR A CB 1 ATOM 119 O OG1 . THR A 1 19 ? 34.630 98.647 37.881 1.00 53.13 ? 19 THR A OG1 1 ATOM 120 C CG2 . THR A 1 19 ? 34.059 98.337 35.639 1.00 52.09 ? 19 THR A CG2 1 ATOM 121 N N . VAL A 1 20 ? 37.224 98.253 34.166 1.00 49.75 ? 20 VAL A N 1 ATOM 122 C CA . VAL A 1 20 ? 37.717 98.479 32.815 1.00 49.40 ? 20 VAL A CA 1 ATOM 123 C C . VAL A 1 20 ? 37.162 97.330 31.988 1.00 49.40 ? 20 VAL A C 1 ATOM 124 O O . VAL A 1 20 ? 37.457 96.164 32.267 1.00 49.33 ? 20 VAL A O 1 ATOM 125 C CB . VAL A 1 20 ? 39.301 98.439 32.719 1.00 48.94 ? 20 VAL A CB 1 ATOM 126 C CG1 . VAL A 1 20 ? 39.773 98.983 31.358 1.00 49.13 ? 20 VAL A CG1 1 ATOM 127 C CG2 . VAL A 1 20 ? 39.985 99.183 33.874 1.00 48.43 ? 20 VAL A CG2 1 ATOM 128 N N . PHE A 1 21 ? 36.362 97.667 30.988 1.00 49.94 ? 21 PHE A N 1 ATOM 129 C CA . PHE A 1 21 ? 35.863 96.705 29.992 1.00 51.40 ? 21 PHE A CA 1 ATOM 130 C C . PHE A 1 21 ? 35.180 95.477 30.602 1.00 52.27 ? 21 PHE A C 1 ATOM 131 O O . PHE A 1 21 ? 35.402 94.354 30.136 1.00 52.22 ? 21 PHE A O 1 ATOM 132 C CB . PHE A 1 21 ? 36.989 96.227 29.050 1.00 51.22 ? 21 PHE A CB 1 ATOM 133 C CG . PHE A 1 21 ? 37.723 97.333 28.336 1.00 50.71 ? 21 PHE A CG 1 ATOM 134 C CD1 . PHE A 1 21 ? 39.014 97.115 27.866 1.00 50.99 ? 21 PHE A CD1 1 ATOM 135 C CD2 . PHE A 1 21 ? 37.130 98.575 28.117 1.00 51.30 ? 21 PHE A CD2 1 ATOM 136 C CE1 . PHE A 1 21 ? 39.717 98.118 27.185 1.00 50.33 ? 21 PHE A CE1 1 ATOM 137 C CE2 . PHE A 1 21 ? 37.816 99.595 27.442 1.00 51.72 ? 21 PHE A CE2 1 ATOM 138 C CZ . PHE A 1 21 ? 39.113 99.361 26.969 1.00 51.22 ? 21 PHE A CZ 1 ATOM 139 N N . GLY A 1 22 ? 34.359 95.699 31.635 1.00 52.36 ? 22 GLY A N 1 ATOM 140 C CA . GLY A 1 22 ? 33.543 94.640 32.222 1.00 52.29 ? 22 GLY A CA 1 ATOM 141 C C . GLY A 1 22 ? 34.377 93.739 33.090 1.00 52.35 ? 22 GLY A C 1 ATOM 142 O O . GLY A 1 22 ? 34.008 92.598 33.381 1.00 52.79 ? 22 GLY A O 1 ATOM 143 N N . GLY A 1 23 ? 35.526 94.248 33.498 1.00 51.82 ? 23 GLY A N 1 ATOM 144 C CA . GLY A 1 23 ? 36.472 93.444 34.251 1.00 51.31 ? 23 GLY A CA 1 ATOM 145 C C . GLY A 1 23 ? 37.055 94.390 35.250 1.00 50.66 ? 23 GLY A C 1 ATOM 146 O O . GLY A 1 23 ? 36.542 95.487 35.410 1.00 51.11 ? 23 GLY A O 1 ATOM 147 N N . THR A 1 24 ? 38.141 93.978 35.889 1.00 50.15 ? 24 THR A N 1 ATOM 148 C CA . THR A 1 24 ? 38.751 94.755 36.956 1.00 49.23 ? 24 THR A CA 1 ATOM 149 C C . THR A 1 24 ? 40.265 94.832 36.846 1.00 48.05 ? 24 THR A C 1 ATOM 150 O O . THR A 1 24 ? 40.934 93.832 36.580 1.00 47.60 ? 24 THR A O 1 ATOM 151 C CB . THR A 1 24 ? 38.361 94.147 38.317 1.00 49.20 ? 24 THR A CB 1 ATOM 152 O OG1 . THR A 1 24 ? 36.975 94.431 38.551 1.00 52.63 ? 24 THR A OG1 1 ATOM 153 C CG2 . THR A 1 24 ? 39.038 94.878 39.463 1.00 48.17 ? 24 THR A CG2 1 ATOM 154 N N . VAL A 1 25 ? 40.798 96.022 37.110 1.00 46.64 ? 25 VAL A N 1 ATOM 155 C CA . VAL A 1 25 ? 42.237 96.208 37.230 1.00 45.41 ? 25 VAL A CA 1 ATOM 156 C C . VAL A 1 25 ? 42.544 96.806 38.608 1.00 45.01 ? 25 VAL A C 1 ATOM 157 O O . VAL A 1 25 ? 41.855 97.718 39.038 1.00 43.53 ? 25 VAL A O 1 ATOM 158 C CB . VAL A 1 25 ? 42.783 97.132 36.085 1.00 45.12 ? 25 VAL A CB 1 ATOM 159 C CG1 . VAL A 1 25 ? 44.253 97.541 36.327 1.00 42.75 ? 25 VAL A CG1 1 ATOM 160 C CG2 . VAL A 1 25 ? 42.628 96.456 34.724 1.00 45.17 ? 25 VAL A CG2 1 ATOM 161 N N . THR A 1 26 ? 43.572 96.280 39.278 1.00 45.50 ? 26 THR A N 1 ATOM 162 C CA . THR A 1 26 ? 44.109 96.887 40.505 1.00 45.73 ? 26 THR A CA 1 ATOM 163 C C . THR A 1 26 ? 45.287 97.849 40.189 1.00 45.64 ? 26 THR A C 1 ATOM 164 O O . THR A 1 26 ? 46.261 97.473 39.491 1.00 45.53 ? 26 THR A O 1 ATOM 165 C CB . THR A 1 26 ? 44.566 95.793 41.481 1.00 45.99 ? 26 THR A CB 1 ATOM 166 O OG1 . THR A 1 26 ? 43.587 94.758 41.514 1.00 46.95 ? 26 THR A OG1 1 ATOM 167 C CG2 . THR A 1 26 ? 44.636 96.307 42.912 1.00 45.24 ? 26 THR A CG2 1 ATOM 168 N N . ALA A 1 27 ? 45.163 99.081 40.697 1.00 44.56 ? 27 ALA A N 1 ATOM 169 C CA . ALA A 1 27 ? 46.105 100.169 40.490 1.00 43.51 ? 27 ALA A CA 1 ATOM 170 C C . ALA A 1 27 ? 46.738 100.592 41.802 1.00 44.25 ? 27 ALA A C 1 ATOM 171 O O . ALA A 1 27 ? 46.036 100.780 42.826 1.00 43.74 ? 27 ALA A O 1 ATOM 172 C CB . ALA A 1 27 ? 45.396 101.358 39.852 1.00 43.28 ? 27 ALA A CB 1 ATOM 173 N N . PHE A 1 28 ? 48.056 100.740 41.769 1.00 43.01 ? 28 PHE A N 1 ATOM 174 C CA . PHE A 1 28 ? 48.810 101.278 42.888 1.00 43.23 ? 28 PHE A CA 1 ATOM 175 C C . PHE A 1 28 ? 49.483 102.517 42.347 1.00 42.22 ? 28 PHE A C 1 ATOM 176 O O . PHE A 1 28 ? 50.515 102.432 41.686 1.00 42.86 ? 28 PHE A O 1 ATOM 177 C CB . PHE A 1 28 ? 49.855 100.293 43.411 1.00 42.81 ? 28 PHE A CB 1 ATOM 178 C CG . PHE A 1 28 ? 49.260 99.031 43.968 1.00 46.37 ? 28 PHE A CG 1 ATOM 179 C CD1 . PHE A 1 28 ? 48.749 98.049 43.109 1.00 48.68 ? 28 PHE A CD1 1 ATOM 180 C CD2 . PHE A 1 28 ? 49.182 98.833 45.354 1.00 48.46 ? 28 PHE A CD2 1 ATOM 181 C CE1 . PHE A 1 28 ? 48.166 96.872 43.602 1.00 50.38 ? 28 PHE A CE1 1 ATOM 182 C CE2 . PHE A 1 28 ? 48.614 97.654 45.877 1.00 50.41 ? 28 PHE A CE2 1 ATOM 183 C CZ . PHE A 1 28 ? 48.098 96.669 44.995 1.00 50.57 ? 28 PHE A CZ 1 ATOM 184 N N . LEU A 1 29 ? 48.869 103.654 42.605 1.00 40.55 ? 29 LEU A N 1 ATOM 185 C CA . LEU A 1 29 ? 49.288 104.898 42.008 1.00 40.75 ? 29 LEU A CA 1 ATOM 186 C C . LEU A 1 29 ? 50.067 105.658 43.056 1.00 40.29 ? 29 LEU A C 1 ATOM 187 O O . LEU A 1 29 ? 49.541 105.899 44.113 1.00 40.97 ? 29 LEU A O 1 ATOM 188 C CB . LEU A 1 29 ? 48.054 105.694 41.592 1.00 39.20 ? 29 LEU A CB 1 ATOM 189 C CG . LEU A 1 29 ? 47.107 105.162 40.518 1.00 39.98 ? 29 LEU A CG 1 ATOM 190 C CD1 . LEU A 1 29 ? 46.187 106.307 40.159 1.00 36.49 ? 29 LEU A CD1 1 ATOM 191 C CD2 . LEU A 1 29 ? 47.851 104.654 39.238 1.00 37.33 ? 29 LEU A CD2 1 ATOM 192 N N . GLY A 1 30 ? 51.314 106.016 42.782 1.00 40.87 ? 30 GLY A N 1 ATOM 193 C CA . GLY A 1 30 ? 52.106 106.840 43.704 1.00 40.20 ? 30 GLY A CA 1 ATOM 194 C C . GLY A 1 30 ? 52.879 106.160 44.791 1.00 41.83 ? 30 GLY A C 1 ATOM 195 O O . GLY A 1 30 ? 52.898 106.652 45.946 1.00 42.69 ? 30 GLY A O 1 ATOM 196 N N . ILE A 1 31 ? 53.549 105.041 44.471 1.00 41.68 ? 31 ILE A N 1 ATOM 197 C CA . ILE A 1 31 ? 54.433 104.378 45.456 1.00 41.67 ? 31 ILE A CA 1 ATOM 198 C C . ILE A 1 31 ? 55.797 105.072 45.464 1.00 41.98 ? 31 ILE A C 1 ATOM 199 O O . ILE A 1 31 ? 56.421 105.222 44.397 1.00 42.46 ? 31 ILE A O 1 ATOM 200 C CB . ILE A 1 31 ? 54.631 102.858 45.099 1.00 41.83 ? 31 ILE A CB 1 ATOM 201 C CG1 . ILE A 1 31 ? 53.296 102.168 44.863 1.00 41.70 ? 31 ILE A CG1 1 ATOM 202 C CG2 . ILE A 1 31 ? 55.505 102.125 46.159 1.00 42.31 ? 31 ILE A CG2 1 ATOM 203 C CD1 . ILE A 1 31 ? 53.438 100.761 44.315 1.00 43.91 ? 31 ILE A CD1 1 ATOM 204 N N . PRO A 1 32 ? 56.329 105.422 46.638 1.00 41.77 ? 32 PRO A N 1 ATOM 205 C CA . PRO A 1 32 ? 57.632 106.045 46.661 1.00 41.51 ? 32 PRO A CA 1 ATOM 206 C C . PRO A 1 32 ? 58.702 104.983 46.355 1.00 41.69 ? 32 PRO A C 1 ATOM 207 O O . PRO A 1 32 ? 58.539 103.829 46.732 1.00 41.87 ? 32 PRO A O 1 ATOM 208 C CB . PRO A 1 32 ? 57.756 106.559 48.105 1.00 41.86 ? 32 PRO A CB 1 ATOM 209 C CG . PRO A 1 32 ? 56.872 105.623 48.925 1.00 42.46 ? 32 PRO A CG 1 ATOM 210 C CD . PRO A 1 32 ? 55.781 105.193 47.997 1.00 41.37 ? 32 PRO A CD 1 ATOM 211 N N . TYR A 1 33 ? 59.783 105.365 45.687 1.00 41.45 ? 33 TYR A N 1 ATOM 212 C CA . TYR A 1 33 ? 60.813 104.394 45.376 1.00 41.93 ? 33 TYR A CA 1 ATOM 213 C C . TYR A 1 33 ? 62.192 104.908 45.709 1.00 42.17 ? 33 TYR A C 1 ATOM 214 O O . TYR A 1 33 ? 63.164 104.180 45.544 1.00 42.24 ? 33 TYR A O 1 ATOM 215 C CB . TYR A 1 33 ? 60.731 103.917 43.906 1.00 41.48 ? 33 TYR A CB 1 ATOM 216 C CG . TYR A 1 33 ? 61.135 104.952 42.861 1.00 38.57 ? 33 TYR A CG 1 ATOM 217 C CD1 . TYR A 1 33 ? 60.171 105.734 42.217 1.00 34.16 ? 33 TYR A CD1 1 ATOM 218 C CD2 . TYR A 1 33 ? 62.456 105.097 42.485 1.00 34.32 ? 33 TYR A CD2 1 ATOM 219 C CE1 . TYR A 1 33 ? 60.537 106.672 41.251 1.00 34.13 ? 33 TYR A CE1 1 ATOM 220 C CE2 . TYR A 1 33 ? 62.828 106.035 41.518 1.00 35.90 ? 33 TYR A CE2 1 ATOM 221 C CZ . TYR A 1 33 ? 61.872 106.811 40.905 1.00 34.42 ? 33 TYR A CZ 1 ATOM 222 O OH . TYR A 1 33 ? 62.256 107.703 39.921 1.00 35.06 ? 33 TYR A OH 1 ATOM 223 N N . ALA A 1 34 ? 62.268 106.158 46.174 1.00 42.34 ? 34 ALA A N 1 ATOM 224 C CA . ALA A 1 34 ? 63.528 106.714 46.696 1.00 42.91 ? 34 ALA A CA 1 ATOM 225 C C . ALA A 1 34 ? 63.262 107.792 47.782 1.00 43.13 ? 34 ALA A C 1 ATOM 226 O O . ALA A 1 34 ? 62.118 108.234 47.950 1.00 42.79 ? 34 ALA A O 1 ATOM 227 C CB . ALA A 1 34 ? 64.382 107.286 45.544 1.00 41.45 ? 34 ALA A CB 1 ATOM 228 N N A GLN A 1 35 ? 64.313 108.190 48.503 0.50 43.66 ? 35 GLN A N 1 ATOM 229 N N B GLN A 1 35 ? 64.311 108.198 48.497 0.50 43.67 ? 35 GLN A N 1 ATOM 230 C CA A GLN A 1 35 ? 64.269 109.370 49.379 0.50 44.26 ? 35 GLN A CA 1 ATOM 231 C CA B GLN A 1 35 ? 64.238 109.346 49.407 0.50 44.29 ? 35 GLN A CA 1 ATOM 232 C C A GLN A 1 35 ? 63.926 110.592 48.536 0.50 44.01 ? 35 GLN A C 1 ATOM 233 C C B GLN A 1 35 ? 63.959 110.603 48.581 0.50 44.03 ? 35 GLN A C 1 ATOM 234 O O A GLN A 1 35 ? 64.528 110.766 47.473 0.50 44.29 ? 35 GLN A O 1 ATOM 235 O O B GLN A 1 35 ? 64.654 110.819 47.584 0.50 44.28 ? 35 GLN A O 1 ATOM 236 C CB A GLN A 1 35 ? 65.627 109.616 50.051 0.50 44.54 ? 35 GLN A CB 1 ATOM 237 C CB B GLN A 1 35 ? 65.563 109.541 50.153 0.50 44.55 ? 35 GLN A CB 1 ATOM 238 C CG A GLN A 1 35 ? 65.711 109.293 51.545 0.50 45.96 ? 35 GLN A CG 1 ATOM 239 C CG B GLN A 1 35 ? 65.924 108.467 51.183 0.50 46.14 ? 35 GLN A CG 1 ATOM 240 C CD A GLN A 1 35 ? 64.720 110.068 52.379 0.50 49.47 ? 35 GLN A CD 1 ATOM 241 C CD B GLN A 1 35 ? 67.239 108.765 51.911 0.50 48.10 ? 35 GLN A CD 1 ATOM 242 O OE1 A GLN A 1 35 ? 64.849 111.299 52.547 0.50 49.45 ? 35 GLN A OE1 1 ATOM 243 O OE1 B GLN A 1 35 ? 68.003 107.841 52.260 0.50 48.72 ? 35 GLN A OE1 1 ATOM 244 N NE2 A GLN A 1 35 ? 63.726 109.352 52.929 0.50 49.14 ? 35 GLN A NE2 1 ATOM 245 N NE2 B GLN A 1 35 ? 67.511 110.047 52.131 0.50 46.47 ? 35 GLN A NE2 1 ATOM 246 N N . PRO A 1 36 ? 62.974 111.424 48.978 1.00 43.64 ? 36 PRO A N 1 ATOM 247 C CA . PRO A 1 36 ? 62.704 112.701 48.291 1.00 43.65 ? 36 PRO A CA 1 ATOM 248 C C . PRO A 1 36 ? 64.030 113.478 48.075 1.00 43.13 ? 36 PRO A C 1 ATOM 249 O O . PRO A 1 36 ? 64.788 113.651 49.011 1.00 44.02 ? 36 PRO A O 1 ATOM 250 C CB . PRO A 1 36 ? 61.728 113.423 49.245 1.00 43.16 ? 36 PRO A CB 1 ATOM 251 C CG . PRO A 1 36 ? 61.003 112.311 49.949 1.00 43.07 ? 36 PRO A CG 1 ATOM 252 C CD . PRO A 1 36 ? 62.044 111.221 50.117 1.00 43.83 ? 36 PRO A CD 1 ATOM 253 N N . PRO A 1 37 ? 64.364 113.839 46.840 1.00 43.59 ? 37 PRO A N 1 ATOM 254 C CA . PRO A 1 37 ? 65.695 114.405 46.565 1.00 43.86 ? 37 PRO A CA 1 ATOM 255 C C . PRO A 1 37 ? 65.730 115.895 46.917 1.00 44.96 ? 37 PRO A C 1 ATOM 256 O O . PRO A 1 37 ? 65.903 116.748 46.045 1.00 45.10 ? 37 PRO A O 1 ATOM 257 C CB . PRO A 1 37 ? 65.870 114.153 45.059 1.00 44.10 ? 37 PRO A CB 1 ATOM 258 C CG . PRO A 1 37 ? 64.425 114.079 44.513 1.00 43.61 ? 37 PRO A CG 1 ATOM 259 C CD . PRO A 1 37 ? 63.541 113.680 45.619 1.00 42.46 ? 37 PRO A CD 1 ATOM 260 N N . LEU A 1 38 ? 65.513 116.190 48.198 1.00 46.59 ? 38 LEU A N 1 ATOM 261 C CA . LEU A 1 38 ? 65.357 117.567 48.689 1.00 48.22 ? 38 LEU A CA 1 ATOM 262 C C . LEU A 1 38 ? 66.569 118.009 49.479 1.00 48.57 ? 38 LEU A C 1 ATOM 263 O O . LEU A 1 38 ? 67.337 117.177 49.966 1.00 49.30 ? 38 LEU A O 1 ATOM 264 C CB . LEU A 1 38 ? 64.108 117.676 49.555 1.00 48.52 ? 38 LEU A CB 1 ATOM 265 C CG . LEU A 1 38 ? 62.843 117.015 49.015 1.00 50.42 ? 38 LEU A CG 1 ATOM 266 C CD1 . LEU A 1 38 ? 61.858 116.732 50.140 1.00 53.27 ? 38 LEU A CD1 1 ATOM 267 C CD2 . LEU A 1 38 ? 62.181 117.891 47.948 1.00 52.34 ? 38 LEU A CD2 1 ATOM 268 N N . GLY A 1 39 ? 66.752 119.326 49.585 1.00 50.21 ? 39 GLY A N 1 ATOM 269 C CA . GLY A 1 39 ? 67.802 119.926 50.433 1.00 49.77 ? 39 GLY A CA 1 ATOM 270 C C . GLY A 1 39 ? 69.209 119.602 50.001 1.00 50.48 ? 39 GLY A C 1 ATOM 271 O O . GLY A 1 39 ? 69.631 119.956 48.896 1.00 51.12 ? 39 GLY A O 1 ATOM 272 N N . ARG A 1 40 ? 69.962 118.931 50.869 1.00 51.19 ? 40 ARG A N 1 ATOM 273 C CA . ARG A 1 40 ? 71.300 118.438 50.505 1.00 51.17 ? 40 ARG A CA 1 ATOM 274 C C . ARG A 1 40 ? 71.293 117.395 49.354 1.00 50.53 ? 40 ARG A C 1 ATOM 275 O O . ARG A 1 40 ? 72.302 117.260 48.653 1.00 51.02 ? 40 ARG A O 1 ATOM 276 C CB . ARG A 1 40 ? 72.038 117.890 51.735 1.00 52.23 ? 40 ARG A CB 1 ATOM 277 C CG . ARG A 1 40 ? 71.369 116.691 52.431 1.00 55.39 ? 40 ARG A CG 1 ATOM 278 C CD . ARG A 1 40 ? 72.244 116.038 53.500 1.00 62.47 ? 40 ARG A CD 1 ATOM 279 N NE . ARG A 1 40 ? 72.531 116.976 54.591 1.00 69.35 ? 40 ARG A NE 1 ATOM 280 C CZ . ARG A 1 40 ? 73.512 116.849 55.504 1.00 72.14 ? 40 ARG A CZ 1 ATOM 281 N NH1 . ARG A 1 40 ? 74.361 115.811 55.486 1.00 71.74 ? 40 ARG A NH1 1 ATOM 282 N NH2 . ARG A 1 40 ? 73.644 117.788 56.445 1.00 71.65 ? 40 ARG A NH2 1 ATOM 283 N N . LEU A 1 41 ? 70.164 116.682 49.170 1.00 49.26 ? 41 LEU A N 1 ATOM 284 C CA . LEU A 1 41 ? 70.000 115.648 48.117 1.00 47.37 ? 41 LEU A CA 1 ATOM 285 C C . LEU A 1 41 ? 69.686 116.207 46.717 1.00 47.02 ? 41 LEU A C 1 ATOM 286 O O . LEU A 1 41 ? 69.735 115.459 45.727 1.00 47.34 ? 41 LEU A O 1 ATOM 287 C CB . LEU A 1 41 ? 68.958 114.579 48.522 1.00 46.41 ? 41 LEU A CB 1 ATOM 288 C CG . LEU A 1 41 ? 69.210 113.856 49.861 1.00 46.39 ? 41 LEU A CG 1 ATOM 289 C CD1 . LEU A 1 41 ? 68.078 112.916 50.245 1.00 44.75 ? 41 LEU A CD1 1 ATOM 290 C CD2 . LEU A 1 41 ? 70.592 113.170 49.927 1.00 43.07 ? 41 LEU A CD2 1 ATOM 291 N N . ARG A 1 42 ? 69.377 117.501 46.620 1.00 45.75 ? 42 ARG A N 1 ATOM 292 C CA . ARG A 1 42 ? 69.091 118.093 45.326 1.00 45.11 ? 42 ARG A CA 1 ATOM 293 C C . ARG A 1 42 ? 70.332 117.970 44.455 1.00 45.03 ? 42 ARG A C 1 ATOM 294 O O . ARG A 1 42 ? 71.440 118.263 44.933 1.00 45.14 ? 42 ARG A O 1 ATOM 295 C CB . ARG A 1 42 ? 68.674 119.569 45.453 1.00 44.58 ? 42 ARG A CB 1 ATOM 296 C CG . ARG A 1 42 ? 68.608 120.260 44.108 1.00 43.60 ? 42 ARG A CG 1 ATOM 297 C CD . ARG A 1 42 ? 68.424 121.762 44.116 1.00 43.01 ? 42 ARG A CD 1 ATOM 298 N NE . ARG A 1 42 ? 67.084 122.148 44.548 1.00 42.32 ? 42 ARG A NE 1 ATOM 299 C CZ . ARG A 1 42 ? 66.711 123.406 44.781 1.00 41.64 ? 42 ARG A CZ 1 ATOM 300 N NH1 . ARG A 1 42 ? 67.577 124.402 44.616 1.00 40.81 ? 42 ARG A NH1 1 ATOM 301 N NH2 . ARG A 1 42 ? 65.475 123.659 45.194 1.00 38.95 ? 42 ARG A NH2 1 ATOM 302 N N . PHE A 1 43 ? 70.144 117.545 43.189 1.00 44.61 ? 43 PHE A N 1 ATOM 303 C CA . PHE A 1 43 ? 71.239 117.245 42.221 1.00 43.46 ? 43 PHE A CA 1 ATOM 304 C C . PHE A 1 43 ? 72.037 115.970 42.485 1.00 43.39 ? 43 PHE A C 1 ATOM 305 O O . PHE A 1 43 ? 72.956 115.666 41.744 1.00 43.57 ? 43 PHE A O 1 ATOM 306 C CB . PHE A 1 43 ? 72.247 118.392 42.071 1.00 43.88 ? 43 PHE A CB 1 ATOM 307 C CG . PHE A 1 43 ? 71.637 119.716 41.772 1.00 45.28 ? 43 PHE A CG 1 ATOM 308 C CD1 . PHE A 1 43 ? 70.879 119.909 40.627 1.00 44.51 ? 43 PHE A CD1 1 ATOM 309 C CD2 . PHE A 1 43 ? 71.862 120.799 42.622 1.00 44.92 ? 43 PHE A CD2 1 ATOM 310 C CE1 . PHE A 1 43 ? 70.338 121.170 40.341 1.00 45.22 ? 43 PHE A CE1 1 ATOM 311 C CE2 . PHE A 1 43 ? 71.328 122.053 42.343 1.00 43.08 ? 43 PHE A CE2 1 ATOM 312 C CZ . PHE A 1 43 ? 70.565 122.238 41.213 1.00 43.90 ? 43 PHE A CZ 1 ATOM 313 N N . LYS A 1 44 ? 71.701 115.221 43.528 1.00 42.91 ? 44 LYS A N 1 ATOM 314 C CA . LYS A 1 44 ? 72.431 113.999 43.787 1.00 44.00 ? 44 LYS A CA 1 ATOM 315 C C . LYS A 1 44 ? 71.671 112.781 43.254 1.00 44.04 ? 44 LYS A C 1 ATOM 316 O O . LYS A 1 44 ? 70.439 112.831 43.058 1.00 44.16 ? 44 LYS A O 1 ATOM 317 C CB . LYS A 1 44 ? 72.650 113.803 45.301 1.00 43.91 ? 44 LYS A CB 1 ATOM 318 C CG . LYS A 1 44 ? 73.639 114.740 45.955 1.00 46.97 ? 44 LYS A CG 1 ATOM 319 C CD . LYS A 1 44 ? 73.873 114.237 47.371 1.00 51.79 ? 44 LYS A CD 1 ATOM 320 C CE . LYS A 1 44 ? 75.345 114.265 47.727 1.00 55.88 ? 44 LYS A CE 1 ATOM 321 N NZ . LYS A 1 44 ? 75.779 115.705 47.841 1.00 59.71 ? 44 LYS A NZ 1 ATOM 322 N N . LYS A 1 45 ? 72.409 111.681 43.087 1.00 43.34 ? 45 LYS A N 1 ATOM 323 C CA . LYS A 1 45 ? 71.847 110.407 42.714 1.00 44.60 ? 45 LYS A CA 1 ATOM 324 C C . LYS A 1 45 ? 70.767 110.097 43.745 1.00 45.61 ? 45 LYS A C 1 ATOM 325 O O . LYS A 1 45 ? 70.880 110.552 44.893 1.00 46.15 ? 45 LYS A O 1 ATOM 326 C CB . LYS A 1 45 ? 72.952 109.308 42.628 1.00 44.24 ? 45 LYS A CB 1 ATOM 327 C CG . LYS A 1 45 ? 73.772 109.399 41.309 1.00 44.36 ? 45 LYS A CG 1 ATOM 328 C CD . LYS A 1 45 ? 75.024 108.511 41.245 1.00 45.01 ? 45 LYS A CD 1 ATOM 329 C CE . LYS A 1 45 ? 74.729 107.005 41.299 1.00 48.76 ? 45 LYS A CE 1 ATOM 330 N NZ . LYS A 1 45 ? 76.006 106.137 41.220 1.00 48.22 ? 45 LYS A NZ 1 ATOM 331 N N . PRO A 1 46 ? 69.720 109.365 43.353 1.00 45.83 ? 46 PRO A N 1 ATOM 332 C CA . PRO A 1 46 ? 68.627 109.076 44.275 1.00 47.02 ? 46 PRO A CA 1 ATOM 333 C C . PRO A 1 46 ? 69.117 108.169 45.412 1.00 49.09 ? 46 PRO A C 1 ATOM 334 O O . PRO A 1 46 ? 69.988 107.341 45.213 1.00 49.76 ? 46 PRO A O 1 ATOM 335 C CB . PRO A 1 46 ? 67.580 108.384 43.385 1.00 46.72 ? 46 PRO A CB 1 ATOM 336 C CG . PRO A 1 46 ? 68.369 107.833 42.188 1.00 44.45 ? 46 PRO A CG 1 ATOM 337 C CD . PRO A 1 46 ? 69.513 108.769 42.018 1.00 44.86 ? 46 PRO A CD 1 ATOM 338 N N . GLN A 1 47 ? 68.581 108.344 46.605 1.00 51.47 ? 47 GLN A N 1 ATOM 339 C CA . GLN A 1 47 ? 69.029 107.576 47.756 1.00 53.26 ? 47 GLN A CA 1 ATOM 340 C C . GLN A 1 47 ? 67.951 106.582 48.071 1.00 54.74 ? 47 GLN A C 1 ATOM 341 O O . GLN A 1 47 ? 66.766 106.851 47.833 1.00 53.58 ? 47 GLN A O 1 ATOM 342 C CB . GLN A 1 47 ? 69.271 108.480 48.971 1.00 52.87 ? 47 GLN A CB 1 ATOM 343 C CG . GLN A 1 47 ? 70.225 109.637 48.725 1.00 55.04 ? 47 GLN A CG 1 ATOM 344 C CD . GLN A 1 47 ? 71.655 109.199 48.466 1.00 59.52 ? 47 GLN A CD 1 ATOM 345 O OE1 . GLN A 1 47 ? 72.204 108.405 49.244 1.00 61.16 ? 47 GLN A OE1 1 ATOM 346 N NE2 . GLN A 1 47 ? 72.275 109.716 47.371 1.00 58.24 ? 47 GLN A NE2 1 ATOM 347 N N . SER A 1 48 ? 68.363 105.437 48.617 1.00 57.65 ? 48 SER A N 1 ATOM 348 C CA . SER A 1 48 ? 67.443 104.335 48.945 1.00 60.61 ? 48 SER A CA 1 ATOM 349 C C . SER A 1 48 ? 66.466 104.735 50.043 1.00 61.70 ? 48 SER A C 1 ATOM 350 O O . SER A 1 48 ? 66.806 105.464 50.976 1.00 62.36 ? 48 SER A O 1 ATOM 351 C CB . SER A 1 48 ? 68.217 103.080 49.359 1.00 61.00 ? 48 SER A CB 1 ATOM 352 O OG . SER A 1 48 ? 68.483 103.119 50.759 1.00 63.96 ? 48 SER A OG 1 ATOM 353 N N . LEU A 1 49 ? 65.254 104.236 49.915 1.00 63.66 ? 49 LEU A N 1 ATOM 354 C CA . LEU A 1 49 ? 64.183 104.566 50.817 1.00 65.73 ? 49 LEU A CA 1 ATOM 355 C C . LEU A 1 49 ? 64.176 103.637 52.031 1.00 67.53 ? 49 LEU A C 1 ATOM 356 O O . LEU A 1 49 ? 64.357 102.413 51.897 1.00 67.99 ? 49 LEU A O 1 ATOM 357 C CB . LEU A 1 49 ? 62.862 104.462 50.070 1.00 65.49 ? 49 LEU A CB 1 ATOM 358 C CG . LEU A 1 49 ? 61.619 105.052 50.701 1.00 65.66 ? 49 LEU A CG 1 ATOM 359 C CD1 . LEU A 1 49 ? 61.806 106.534 51.043 1.00 66.01 ? 49 LEU A CD1 1 ATOM 360 C CD2 . LEU A 1 49 ? 60.484 104.830 49.721 1.00 67.65 ? 49 LEU A CD2 1 ATOM 361 N N . THR A 1 50 ? 63.972 104.231 53.206 1.00 69.02 ? 50 THR A N 1 ATOM 362 C CA . THR A 1 50 ? 63.861 103.468 54.434 1.00 70.90 ? 50 THR A CA 1 ATOM 363 C C . THR A 1 50 ? 62.415 103.055 54.667 1.00 71.27 ? 50 THR A C 1 ATOM 364 O O . THR A 1 50 ? 61.476 103.789 54.343 1.00 70.92 ? 50 THR A O 1 ATOM 365 C CB . THR A 1 50 ? 64.501 104.231 55.644 1.00 71.44 ? 50 THR A CB 1 ATOM 366 O OG1 . THR A 1 50 ? 65.835 103.732 55.861 1.00 72.99 ? 50 THR A OG1 1 ATOM 367 C CG2 . THR A 1 50 ? 63.816 103.889 56.973 1.00 72.47 ? 50 THR A CG2 1 ATOM 368 N N . LYS A 1 51 ? 62.273 101.852 55.213 1.00 72.02 ? 51 LYS A N 1 ATOM 369 C CA . LYS A 1 51 ? 60.989 101.213 55.467 1.00 72.97 ? 51 LYS A CA 1 ATOM 370 C C . LYS A 1 51 ? 59.995 102.086 56.239 1.00 72.89 ? 51 LYS A C 1 ATOM 371 O O . LYS A 1 51 ? 60.391 102.927 57.059 1.00 73.09 ? 51 LYS A O 1 ATOM 372 C CB . LYS A 1 51 ? 61.216 99.885 56.217 1.00 73.68 ? 51 LYS A CB 1 ATOM 373 C CG . LYS A 1 51 ? 62.226 99.976 57.388 1.00 75.88 ? 51 LYS A CG 1 ATOM 374 C CD . LYS A 1 51 ? 62.244 98.719 58.278 1.00 77.37 ? 51 LYS A CD 1 ATOM 375 C CE . LYS A 1 51 ? 63.502 98.710 59.162 1.00 78.93 ? 51 LYS A CE 1 ATOM 376 N NZ . LYS A 1 51 ? 63.467 97.654 60.219 1.00 78.13 ? 51 LYS A NZ 1 ATOM 377 N N . TRP A 1 52 ? 58.711 101.893 55.944 1.00 72.48 ? 52 TRP A N 1 ATOM 378 C CA . TRP A 1 52 ? 57.622 102.427 56.758 1.00 72.14 ? 52 TRP A CA 1 ATOM 379 C C . TRP A 1 52 ? 56.819 101.269 57.349 1.00 72.02 ? 52 TRP A C 1 ATOM 380 O O . TRP A 1 52 ? 56.955 100.109 56.927 1.00 72.13 ? 52 TRP A O 1 ATOM 381 C CB . TRP A 1 52 ? 56.698 103.360 55.954 1.00 71.58 ? 52 TRP A CB 1 ATOM 382 C CG . TRP A 1 52 ? 56.008 102.687 54.809 1.00 71.77 ? 52 TRP A CG 1 ATOM 383 C CD1 . TRP A 1 52 ? 54.791 102.051 54.828 1.00 71.22 ? 52 TRP A CD1 1 ATOM 384 C CD2 . TRP A 1 52 ? 56.496 102.564 53.467 1.00 71.45 ? 52 TRP A CD2 1 ATOM 385 N NE1 . TRP A 1 52 ? 54.498 101.547 53.582 1.00 69.65 ? 52 TRP A NE1 1 ATOM 386 C CE2 . TRP A 1 52 ? 55.528 101.845 52.728 1.00 69.99 ? 52 TRP A CE2 1 ATOM 387 C CE3 . TRP A 1 52 ? 57.661 102.988 52.809 1.00 71.57 ? 52 TRP A CE3 1 ATOM 388 C CZ2 . TRP A 1 52 ? 55.686 101.547 51.373 1.00 69.56 ? 52 TRP A CZ2 1 ATOM 389 C CZ3 . TRP A 1 52 ? 57.811 102.695 51.456 1.00 70.97 ? 52 TRP A CZ3 1 ATOM 390 C CH2 . TRP A 1 52 ? 56.825 101.983 50.757 1.00 69.58 ? 52 TRP A CH2 1 ATOM 391 N N . SER A 1 53 ? 56.011 101.607 58.350 1.00 71.67 ? 53 SER A N 1 ATOM 392 C CA . SER A 1 53 ? 54.997 100.723 58.904 1.00 71.16 ? 53 SER A CA 1 ATOM 393 C C . SER A 1 53 ? 53.700 101.463 58.674 1.00 70.61 ? 53 SER A C 1 ATOM 394 O O . SER A 1 53 ? 53.714 102.642 58.291 1.00 71.37 ? 53 SER A O 1 ATOM 395 C CB . SER A 1 53 ? 55.231 100.466 60.397 1.00 71.54 ? 53 SER A CB 1 ATOM 396 O OG . SER A 1 53 ? 56.581 100.088 60.641 1.00 71.71 ? 53 SER A OG 1 ATOM 397 N N . ASP A 1 54 ? 52.588 100.782 58.920 1.00 69.29 ? 54 ASP A N 1 ATOM 398 C CA . ASP A 1 54 ? 51.275 101.214 58.452 1.00 67.85 ? 54 ASP A CA 1 ATOM 399 C C . ASP A 1 54 ? 51.230 101.083 56.921 1.00 66.84 ? 54 ASP A C 1 ATOM 400 O O . ASP A 1 54 ? 52.221 100.692 56.288 1.00 66.87 ? 54 ASP A O 1 ATOM 401 C CB . ASP A 1 54 ? 50.843 102.598 59.010 0.10 67.91 ? 54 ASP A CB 1 ATOM 402 C CG . ASP A 1 54 ? 51.128 103.761 58.058 0.10 67.67 ? 54 ASP A CG 1 ATOM 403 O OD1 . ASP A 1 54 ? 50.418 103.898 57.039 0.10 67.71 ? 54 ASP A OD1 1 ATOM 404 O OD2 . ASP A 1 54 ? 52.014 104.616 58.274 0.10 67.20 ? 54 ASP A OD2 1 ATOM 405 N N . ILE A 1 55 ? 50.068 101.358 56.347 1.00 65.08 ? 55 ILE A N 1 ATOM 406 C CA . ILE A 1 55 ? 49.834 101.066 54.965 1.00 63.39 ? 55 ILE A CA 1 ATOM 407 C C . ILE A 1 55 ? 49.966 102.353 54.185 1.00 62.61 ? 55 ILE A C 1 ATOM 408 O O . ILE A 1 55 ? 49.202 103.306 54.418 1.00 62.14 ? 55 ILE A O 1 ATOM 409 C CB . ILE A 1 55 ? 48.445 100.419 54.787 1.00 63.89 ? 55 ILE A CB 1 ATOM 410 C CG1 . ILE A 1 55 ? 48.380 99.108 55.602 1.00 62.97 ? 55 ILE A CG1 1 ATOM 411 C CG2 . ILE A 1 55 ? 48.109 100.229 53.270 1.00 62.33 ? 55 ILE A CG2 1 ATOM 412 C CD1 . ILE A 1 55 ? 47.011 98.438 55.663 1.00 61.64 ? 55 ILE A CD1 1 ATOM 413 N N . TRP A 1 56 ? 50.973 102.398 53.296 1.00 60.94 ? 56 TRP A N 1 ATOM 414 C CA . TRP A 1 56 ? 51.082 103.491 52.332 1.00 58.80 ? 56 TRP A CA 1 ATOM 415 C C . TRP A 1 56 ? 49.917 103.437 51.347 1.00 58.38 ? 56 TRP A C 1 ATOM 416 O O . TRP A 1 56 ? 49.635 102.405 50.735 1.00 58.08 ? 56 TRP A O 1 ATOM 417 C CB . TRP A 1 56 ? 52.398 103.467 51.579 1.00 58.44 ? 56 TRP A CB 1 ATOM 418 C CG . TRP A 1 56 ? 52.501 104.647 50.654 1.00 56.19 ? 56 TRP A CG 1 ATOM 419 C CD1 . TRP A 1 56 ? 51.780 104.871 49.508 1.00 52.35 ? 56 TRP A CD1 1 ATOM 420 C CD2 . TRP A 1 56 ? 53.342 105.784 50.824 1.00 55.22 ? 56 TRP A CD2 1 ATOM 421 N NE1 . TRP A 1 56 ? 52.131 106.079 48.955 1.00 53.71 ? 56 TRP A NE1 1 ATOM 422 C CE2 . TRP A 1 56 ? 53.099 106.656 49.732 1.00 53.96 ? 56 TRP A CE2 1 ATOM 423 C CE3 . TRP A 1 56 ? 54.309 106.143 51.769 1.00 55.38 ? 56 TRP A CE3 1 ATOM 424 C CZ2 . TRP A 1 56 ? 53.775 107.864 49.570 1.00 55.37 ? 56 TRP A CZ2 1 ATOM 425 C CZ3 . TRP A 1 56 ? 54.991 107.352 51.602 1.00 57.92 ? 56 TRP A CZ3 1 ATOM 426 C CH2 . TRP A 1 56 ? 54.714 108.198 50.515 1.00 54.84 ? 56 TRP A CH2 1 ATOM 427 N N . ASN A 1 57 ? 49.239 104.565 51.217 1.00 57.80 ? 57 ASN A N 1 ATOM 428 C CA . ASN A 1 57 ? 48.079 104.678 50.359 1.00 57.34 ? 57 ASN A CA 1 ATOM 429 C C . ASN A 1 57 ? 48.505 105.099 48.951 1.00 55.88 ? 57 ASN A C 1 ATOM 430 O O . ASN A 1 57 ? 48.892 106.245 48.728 1.00 55.27 ? 57 ASN A O 1 ATOM 431 C CB . ASN A 1 57 ? 47.069 105.671 50.969 1.00 59.02 ? 57 ASN A CB 1 ATOM 432 C CG . ASN A 1 57 ? 46.199 105.034 52.073 1.00 61.94 ? 57 ASN A CG 1 ATOM 433 O OD1 . ASN A 1 57 ? 46.020 103.808 52.100 1.00 65.17 ? 57 ASN A OD1 1 ATOM 434 N ND2 . ASN A 1 57 ? 45.647 105.871 52.962 1.00 66.06 ? 57 ASN A ND2 1 ATOM 435 N N . ALA A 1 58 ? 48.465 104.136 48.027 1.00 53.74 ? 58 ALA A N 1 ATOM 436 C CA . ALA A 1 58 ? 48.822 104.340 46.624 1.00 51.61 ? 58 ALA A CA 1 ATOM 437 C C . ALA A 1 58 ? 47.543 104.417 45.822 1.00 50.19 ? 58 ALA A C 1 ATOM 438 O O . ALA A 1 58 ? 47.244 103.555 45.011 1.00 50.45 ? 58 ALA A O 1 ATOM 439 C CB . ALA A 1 58 ? 49.699 103.195 46.129 1.00 51.35 ? 58 ALA A CB 1 ATOM 440 N N . THR A 1 59 ? 46.782 105.474 46.057 1.00 48.80 ? 59 THR A N 1 ATOM 441 C CA . THR A 1 59 ? 45.408 105.533 45.572 1.00 47.04 ? 59 THR A CA 1 ATOM 442 C C . THR A 1 59 ? 45.226 106.751 44.687 1.00 45.97 ? 59 THR A C 1 ATOM 443 O O . THR A 1 59 ? 44.140 106.989 44.150 1.00 45.45 ? 59 THR A O 1 ATOM 444 C CB . THR A 1 59 ? 44.409 105.530 46.770 1.00 47.47 ? 59 THR A CB 1 ATOM 445 O OG1 . THR A 1 59 ? 44.966 106.292 47.856 1.00 48.17 ? 59 THR A OG1 1 ATOM 446 C CG2 . THR A 1 59 ? 44.316 104.116 47.367 1.00 45.35 ? 59 THR A CG2 1 ATOM 447 N N . LYS A 1 60 ? 46.296 107.534 44.546 1.00 44.22 ? 60 LYS A N 1 ATOM 448 C CA . LYS A 1 60 ? 46.299 108.606 43.553 1.00 43.78 ? 60 LYS A CA 1 ATOM 449 C C . LYS A 1 60 ? 47.691 108.848 43.008 1.00 41.51 ? 60 LYS A C 1 ATOM 450 O O . LYS A 1 60 ? 48.662 108.496 43.646 1.00 40.60 ? 60 LYS A O 1 ATOM 451 C CB . LYS A 1 60 ? 45.677 109.911 44.121 1.00 44.11 ? 60 LYS A CB 1 ATOM 452 C CG . LYS A 1 60 ? 46.352 110.546 45.309 1.00 46.61 ? 60 LYS A CG 1 ATOM 453 C CD . LYS A 1 60 ? 45.630 111.934 45.622 1.00 53.47 ? 60 LYS A CD 1 ATOM 454 C CE . LYS A 1 60 ? 46.612 113.047 46.152 1.00 58.29 ? 60 LYS A CE 1 ATOM 455 N NZ . LYS A 1 60 ? 46.217 114.527 45.846 1.00 58.13 ? 60 LYS A NZ 1 ATOM 456 N N . TYR A 1 61 ? 47.772 109.439 41.822 1.00 40.03 ? 61 TYR A N 1 ATOM 457 C CA . TYR A 1 61 ? 49.065 109.868 41.260 1.00 39.03 ? 61 TYR A CA 1 ATOM 458 C C . TYR A 1 61 ? 49.794 110.850 42.153 1.00 38.48 ? 61 TYR A C 1 ATOM 459 O O . TYR A 1 61 ? 49.179 111.715 42.773 1.00 38.49 ? 61 TYR A O 1 ATOM 460 C CB . TYR A 1 61 ? 48.846 110.546 39.915 1.00 38.59 ? 61 TYR A CB 1 ATOM 461 C CG . TYR A 1 61 ? 48.364 109.657 38.778 1.00 38.59 ? 61 TYR A CG 1 ATOM 462 C CD1 . TYR A 1 61 ? 49.164 108.618 38.274 1.00 38.25 ? 61 TYR A CD1 1 ATOM 463 C CD2 . TYR A 1 61 ? 47.152 109.911 38.149 1.00 40.01 ? 61 TYR A CD2 1 ATOM 464 C CE1 . TYR A 1 61 ? 48.727 107.816 37.164 1.00 37.36 ? 61 TYR A CE1 1 ATOM 465 C CE2 . TYR A 1 61 ? 46.712 109.136 37.059 1.00 37.24 ? 61 TYR A CE2 1 ATOM 466 C CZ . TYR A 1 61 ? 47.517 108.089 36.581 1.00 38.02 ? 61 TYR A CZ 1 ATOM 467 O OH . TYR A 1 61 ? 47.077 107.339 35.514 1.00 38.86 ? 61 TYR A OH 1 ATOM 468 N N . ALA A 1 62 ? 51.107 110.725 42.210 1.00 38.05 ? 62 ALA A N 1 ATOM 469 C CA . ALA A 1 62 ? 51.917 111.576 43.074 1.00 38.21 ? 62 ALA A CA 1 ATOM 470 C C . ALA A 1 62 ? 52.291 112.865 42.359 1.00 38.34 ? 62 ALA A C 1 ATOM 471 O O . ALA A 1 62 ? 51.888 113.081 41.201 1.00 38.81 ? 62 ALA A O 1 ATOM 472 C CB . ALA A 1 62 ? 53.170 110.815 43.550 1.00 37.61 ? 62 ALA A CB 1 ATOM 473 N N . ASN A 1 63 ? 53.038 113.729 43.039 1.00 37.26 ? 63 ASN A N 1 ATOM 474 C CA . ASN A 1 63 ? 53.599 114.909 42.409 1.00 37.25 ? 63 ASN A CA 1 ATOM 475 C C . ASN A 1 63 ? 54.451 114.557 41.164 1.00 36.99 ? 63 ASN A C 1 ATOM 476 O O . ASN A 1 63 ? 55.209 113.594 41.213 1.00 36.02 ? 63 ASN A O 1 ATOM 477 C CB . ASN A 1 63 ? 54.548 115.625 43.370 1.00 37.74 ? 63 ASN A CB 1 ATOM 478 C CG . ASN A 1 63 ? 53.868 116.085 44.663 1.00 38.79 ? 63 ASN A CG 1 ATOM 479 O OD1 . ASN A 1 63 ? 52.701 116.425 44.684 1.00 36.63 ? 63 ASN A OD1 1 ATOM 480 N ND2 . ASN A 1 63 ? 54.632 116.089 45.742 1.00 42.58 ? 63 ASN A ND2 1 ATOM 481 N N . SER A 1 64 ? 54.364 115.402 40.126 1.00 36.37 ? 64 SER A N 1 ATOM 482 C CA . SER A 1 64 ? 55.261 115.381 38.974 1.00 37.09 ? 64 SER A CA 1 ATOM 483 C C . SER A 1 64 ? 56.508 116.200 39.356 1.00 38.46 ? 64 SER A C 1 ATOM 484 O O . SER A 1 64 ? 56.416 117.098 40.193 1.00 39.68 ? 64 SER A O 1 ATOM 485 C CB . SER A 1 64 ? 54.610 116.036 37.755 1.00 35.20 ? 64 SER A CB 1 ATOM 486 O OG . SER A 1 64 ? 53.345 115.479 37.428 1.00 35.17 ? 64 SER A OG 1 ATOM 487 N N . CYS A 1 65 ? 57.649 115.916 38.722 1.00 37.64 ? 65 CYS A N 1 ATOM 488 C CA . CYS A 1 65 ? 58.882 116.646 38.980 1.00 37.84 ? 65 CYS A CA 1 ATOM 489 C C . CYS A 1 65 ? 58.786 118.088 38.511 1.00 37.37 ? 65 CYS A C 1 ATOM 490 O O . CYS A 1 65 ? 57.992 118.375 37.642 1.00 37.25 ? 65 CYS A O 1 ATOM 491 C CB . CYS A 1 65 ? 60.067 115.922 38.308 1.00 37.45 ? 65 CYS A CB 1 ATOM 492 S SG . CYS A 1 65 ? 60.219 114.276 39.014 1.00 38.59 ? 65 CYS A SG 1 HETATM 493 N N . CSS A 1 66 ? 59.610 118.977 39.074 1.00 37.53 ? 66 CSS A N 1 HETATM 494 C CA . CSS A 1 66 ? 59.572 120.380 38.682 1.00 39.07 ? 66 CSS A CA 1 HETATM 495 C CB . CSS A 1 66 ? 60.537 121.235 39.517 1.00 39.52 ? 66 CSS A CB 1 HETATM 496 S SG . CSS A 1 66 ? 60.312 121.088 41.299 1.00 45.37 ? 66 CSS A SG 1 HETATM 497 S SD . CSS A 1 66 ? 58.587 122.168 41.319 1.00 54.84 ? 66 CSS A SD 1 HETATM 498 C C . CSS A 1 66 ? 59.980 120.493 37.234 1.00 39.47 ? 66 CSS A C 1 HETATM 499 O O . CSS A 1 66 ? 60.913 119.821 36.775 1.00 39.27 ? 66 CSS A O 1 ATOM 500 N N . GLN A 1 67 ? 59.302 121.360 36.517 1.00 38.99 ? 67 GLN A N 1 ATOM 501 C CA . GLN A 1 67 ? 59.575 121.492 35.102 1.00 39.48 ? 67 GLN A CA 1 ATOM 502 C C . GLN A 1 67 ? 58.867 122.743 34.591 1.00 39.37 ? 67 GLN A C 1 ATOM 503 O O . GLN A 1 67 ? 57.806 123.101 35.085 1.00 39.29 ? 67 GLN A O 1 ATOM 504 C CB . GLN A 1 67 ? 59.063 120.258 34.343 1.00 37.85 ? 67 GLN A CB 1 ATOM 505 C CG . GLN A 1 67 ? 57.546 119.953 34.587 1.00 39.07 ? 67 GLN A CG 1 ATOM 506 C CD . GLN A 1 67 ? 57.127 118.572 34.038 1.00 37.99 ? 67 GLN A CD 1 ATOM 507 O OE1 . GLN A 1 67 ? 56.716 118.458 32.892 1.00 34.24 ? 67 GLN A OE1 1 ATOM 508 N NE2 . GLN A 1 67 ? 57.192 117.552 34.883 1.00 36.63 ? 67 GLN A NE2 1 ATOM 509 N N . ASN A 1 68 ? 59.437 123.357 33.571 1.00 39.93 ? 68 ASN A N 1 ATOM 510 C CA . ASN A 1 68 ? 58.710 124.334 32.820 1.00 41.35 ? 68 ASN A CA 1 ATOM 511 C C . ASN A 1 68 ? 57.554 123.703 32.071 1.00 41.92 ? 68 ASN A C 1 ATOM 512 O O . ASN A 1 68 ? 57.568 122.496 31.751 1.00 41.49 ? 68 ASN A O 1 ATOM 513 C CB . ASN A 1 68 ? 59.665 125.119 31.925 1.00 40.93 ? 68 ASN A CB 1 ATOM 514 C CG . ASN A 1 68 ? 60.655 125.938 32.753 1.00 43.68 ? 68 ASN A CG 1 ATOM 515 O OD1 . ASN A 1 68 ? 60.251 126.768 33.596 1.00 45.93 ? 68 ASN A OD1 1 ATOM 516 N ND2 . ASN A 1 68 ? 61.941 125.680 32.567 1.00 41.71 ? 68 ASN A ND2 1 ATOM 517 N N . ILE A 1 69 ? 56.540 124.521 31.821 1.00 42.82 ? 69 ILE A N 1 ATOM 518 C CA . ILE A 1 69 ? 55.337 124.099 31.115 1.00 44.15 ? 69 ILE A CA 1 ATOM 519 C C . ILE A 1 69 ? 55.239 124.769 29.748 1.00 44.79 ? 69 ILE A C 1 ATOM 520 O O . ILE A 1 69 ? 55.634 125.927 29.594 1.00 43.74 ? 69 ILE A O 1 ATOM 521 C CB . ILE A 1 69 ? 54.105 124.429 31.995 1.00 45.36 ? 69 ILE A CB 1 ATOM 522 C CG1 . ILE A 1 69 ? 53.864 123.302 33.008 1.00 46.26 ? 69 ILE A CG1 1 ATOM 523 C CG2 . ILE A 1 69 ? 52.845 124.557 31.175 1.00 45.46 ? 69 ILE A CG2 1 ATOM 524 C CD1 . ILE A 1 69 ? 54.683 123.345 34.170 1.00 49.08 ? 69 ILE A CD1 1 ATOM 525 N N . ASP A 1 70 ? 54.707 124.027 28.768 1.00 44.89 ? 70 ASP A N 1 ATOM 526 C CA . ASP A 1 70 ? 54.307 124.577 27.458 1.00 46.41 ? 70 ASP A CA 1 ATOM 527 C C . ASP A 1 70 ? 53.097 125.545 27.591 1.00 46.74 ? 70 ASP A C 1 ATOM 528 O O . ASP A 1 70 ? 51.932 125.099 27.703 1.00 46.52 ? 70 ASP A O 1 ATOM 529 C CB . ASP A 1 70 ? 53.957 123.413 26.496 1.00 46.19 ? 70 ASP A CB 1 ATOM 530 C CG . ASP A 1 70 ? 53.606 123.877 25.076 1.00 46.69 ? 70 ASP A CG 1 ATOM 531 O OD1 . ASP A 1 70 ? 53.285 123.004 24.244 1.00 45.34 ? 70 ASP A OD1 1 ATOM 532 O OD2 . ASP A 1 70 ? 53.624 125.064 24.668 1.00 49.72 ? 70 ASP A OD2 1 ATOM 533 N N . GLN A 1 71 ? 53.391 126.847 27.551 1.00 46.65 ? 71 GLN A N 1 ATOM 534 C CA . GLN A 1 71 ? 52.364 127.914 27.560 1.00 47.47 ? 71 GLN A CA 1 ATOM 535 C C . GLN A 1 71 ? 52.121 128.536 26.183 1.00 46.63 ? 71 GLN A C 1 ATOM 536 O O . GLN A 1 71 ? 51.464 129.591 26.086 1.00 45.81 ? 71 GLN A O 1 ATOM 537 C CB . GLN A 1 71 ? 52.764 129.049 28.500 1.00 47.93 ? 71 GLN A CB 1 ATOM 538 C CG . GLN A 1 71 ? 53.097 128.627 29.931 1.00 53.22 ? 71 GLN A CG 1 ATOM 539 C CD . GLN A 1 71 ? 53.979 129.660 30.642 1.00 59.36 ? 71 GLN A CD 1 ATOM 540 O OE1 . GLN A 1 71 ? 54.591 129.361 31.675 1.00 61.82 ? 71 GLN A OE1 1 ATOM 541 N NE2 . GLN A 1 71 ? 54.032 130.880 30.097 1.00 60.68 ? 71 GLN A NE2 1 ATOM 542 N N . SER A 1 72 ? 52.627 127.887 25.125 1.00 45.03 ? 72 SER A N 1 ATOM 543 C CA . SER A 1 72 ? 52.440 128.406 23.763 1.00 44.21 ? 72 SER A CA 1 ATOM 544 C C . SER A 1 72 ? 50.995 128.467 23.318 1.00 42.90 ? 72 SER A C 1 ATOM 545 O O . SER A 1 72 ? 50.631 129.382 22.608 1.00 43.77 ? 72 SER A O 1 ATOM 546 C CB . SER A 1 72 ? 53.301 127.659 22.715 1.00 43.91 ? 72 SER A CB 1 ATOM 547 O OG . SER A 1 72 ? 54.671 127.770 23.065 1.00 44.09 ? 72 SER A OG 1 ATOM 548 N N . PHE A 1 73 ? 50.171 127.507 23.739 1.00 41.50 ? 73 PHE A N 1 ATOM 549 C CA . PHE A 1 73 ? 48.764 127.489 23.335 1.00 40.91 ? 73 PHE A CA 1 ATOM 550 C C . PHE A 1 73 ? 47.771 127.274 24.492 1.00 40.61 ? 73 PHE A C 1 ATOM 551 O O . PHE A 1 73 ? 47.175 126.205 24.594 1.00 40.35 ? 73 PHE A O 1 ATOM 552 C CB . PHE A 1 73 ? 48.572 126.434 22.251 1.00 41.38 ? 73 PHE A CB 1 ATOM 553 C CG . PHE A 1 73 ? 49.573 126.529 21.113 1.00 41.46 ? 73 PHE A CG 1 ATOM 554 C CD1 . PHE A 1 73 ? 49.468 127.534 20.154 1.00 42.45 ? 73 PHE A CD1 1 ATOM 555 C CD2 . PHE A 1 73 ? 50.622 125.613 21.013 1.00 40.82 ? 73 PHE A CD2 1 ATOM 556 C CE1 . PHE A 1 73 ? 50.386 127.614 19.091 1.00 41.50 ? 73 PHE A CE1 1 ATOM 557 C CE2 . PHE A 1 73 ? 51.540 125.686 19.972 1.00 40.05 ? 73 PHE A CE2 1 ATOM 558 C CZ . PHE A 1 73 ? 51.420 126.686 19.004 1.00 40.02 ? 73 PHE A CZ 1 ATOM 559 N N . PRO A 1 74 ? 47.574 128.269 25.364 1.00 40.41 ? 74 PRO A N 1 ATOM 560 C CA . PRO A 1 74 ? 46.650 128.096 26.501 1.00 40.57 ? 74 PRO A CA 1 ATOM 561 C C . PRO A 1 74 ? 45.246 127.683 26.033 1.00 40.33 ? 74 PRO A C 1 ATOM 562 O O . PRO A 1 74 ? 44.752 128.182 25.021 1.00 40.94 ? 74 PRO A O 1 ATOM 563 C CB . PRO A 1 74 ? 46.642 129.473 27.160 1.00 40.44 ? 74 PRO A CB 1 ATOM 564 C CG . PRO A 1 74 ? 47.969 130.033 26.810 1.00 41.08 ? 74 PRO A CG 1 ATOM 565 C CD . PRO A 1 74 ? 48.145 129.626 25.331 1.00 39.73 ? 74 PRO A CD 1 ATOM 566 N N . GLY A 1 75 ? 44.668 126.712 26.720 1.00 39.78 ? 75 GLY A N 1 ATOM 567 C CA . GLY A 1 75 ? 43.306 126.260 26.447 1.00 39.87 ? 75 GLY A CA 1 ATOM 568 C C . GLY A 1 75 ? 43.217 125.301 25.296 1.00 39.94 ? 75 GLY A C 1 ATOM 569 O O . GLY A 1 75 ? 42.133 124.838 24.957 1.00 39.06 ? 75 GLY A O 1 ATOM 570 N N . PHE A 1 76 ? 44.361 125.032 24.660 1.00 40.12 ? 76 PHE A N 1 ATOM 571 C CA . PHE A 1 76 ? 44.419 124.119 23.491 1.00 38.96 ? 76 PHE A CA 1 ATOM 572 C C . PHE A 1 76 ? 44.823 122.707 23.902 1.00 38.52 ? 76 PHE A C 1 ATOM 573 O O . PHE A 1 76 ? 45.919 122.494 24.396 1.00 38.19 ? 76 PHE A O 1 ATOM 574 C CB . PHE A 1 76 ? 45.376 124.641 22.404 1.00 38.14 ? 76 PHE A CB 1 ATOM 575 C CG . PHE A 1 76 ? 45.475 123.733 21.185 1.00 37.16 ? 76 PHE A CG 1 ATOM 576 C CD1 . PHE A 1 76 ? 44.327 123.345 20.482 1.00 36.39 ? 76 PHE A CD1 1 ATOM 577 C CD2 . PHE A 1 76 ? 46.719 123.262 20.748 1.00 34.99 ? 76 PHE A CD2 1 ATOM 578 C CE1 . PHE A 1 76 ? 44.430 122.513 19.352 1.00 36.89 ? 76 PHE A CE1 1 ATOM 579 C CE2 . PHE A 1 76 ? 46.835 122.445 19.633 1.00 33.98 ? 76 PHE A CE2 1 ATOM 580 C CZ . PHE A 1 76 ? 45.715 122.092 18.922 1.00 36.11 ? 76 PHE A CZ 1 ATOM 581 N N . HIS A 1 77 ? 43.948 121.747 23.635 1.00 38.14 ? 77 HIS A N 1 ATOM 582 C CA . HIS A 1 77 ? 44.172 120.379 24.051 1.00 38.92 ? 77 HIS A CA 1 ATOM 583 C C . HIS A 1 77 ? 45.440 119.711 23.446 1.00 38.93 ? 77 HIS A C 1 ATOM 584 O O . HIS A 1 77 ? 46.096 118.892 24.121 1.00 39.14 ? 77 HIS A O 1 ATOM 585 C CB . HIS A 1 77 ? 42.922 119.528 23.792 1.00 38.72 ? 77 HIS A CB 1 ATOM 586 C CG . HIS A 1 77 ? 43.043 118.146 24.341 1.00 40.62 ? 77 HIS A CG 1 ATOM 587 N ND1 . HIS A 1 77 ? 43.283 117.898 25.676 1.00 42.15 ? 77 HIS A ND1 1 ATOM 588 C CD2 . HIS A 1 77 ? 42.993 116.937 23.736 1.00 42.73 ? 77 HIS A CD2 1 ATOM 589 C CE1 . HIS A 1 77 ? 43.374 116.596 25.872 1.00 42.66 ? 77 HIS A CE1 1 ATOM 590 N NE2 . HIS A 1 77 ? 43.216 115.992 24.709 1.00 43.99 ? 77 HIS A NE2 1 ATOM 591 N N . GLY A 1 78 ? 45.761 120.037 22.186 1.00 38.76 ? 78 GLY A N 1 ATOM 592 C CA . GLY A 1 78 ? 46.919 119.455 21.482 1.00 37.89 ? 78 GLY A CA 1 ATOM 593 C C . GLY A 1 78 ? 48.200 119.631 22.268 1.00 39.25 ? 78 GLY A C 1 ATOM 594 O O . GLY A 1 78 ? 49.027 118.739 22.315 1.00 39.37 ? 78 GLY A O 1 ATOM 595 N N . SER A 1 79 ? 48.361 120.779 22.920 1.00 39.60 ? 79 SER A N 1 ATOM 596 C CA . SER A 1 79 ? 49.547 121.042 23.688 1.00 39.18 ? 79 SER A CA 1 ATOM 597 C C . SER A 1 79 ? 49.363 120.713 25.119 1.00 39.57 ? 79 SER A C 1 ATOM 598 O O . SER A 1 79 ? 50.287 120.192 25.748 1.00 38.98 ? 79 SER A O 1 ATOM 599 C CB . SER A 1 79 ? 50.019 122.504 23.561 1.00 39.73 ? 79 SER A CB 1 ATOM 600 O OG . SER A 1 79 ? 48.978 123.447 23.731 1.00 41.30 ? 79 SER A OG 1 ATOM 601 N N . GLU A 1 80 ? 48.187 121.042 25.657 1.00 39.14 ? 80 GLU A N 1 ATOM 602 C CA . GLU A 1 80 ? 47.977 120.929 27.083 1.00 39.78 ? 80 GLU A CA 1 ATOM 603 C C . GLU A 1 80 ? 47.833 119.492 27.531 1.00 38.83 ? 80 GLU A C 1 ATOM 604 O O . GLU A 1 80 ? 48.042 119.200 28.699 1.00 39.26 ? 80 GLU A O 1 ATOM 605 C CB . GLU A 1 80 ? 46.762 121.774 27.570 1.00 40.74 ? 80 GLU A CB 1 ATOM 606 C CG . GLU A 1 80 ? 46.909 123.294 27.400 1.00 42.85 ? 80 GLU A CG 1 ATOM 607 C CD . GLU A 1 80 ? 45.807 124.110 28.128 1.00 45.56 ? 80 GLU A CD 1 ATOM 608 O OE1 . GLU A 1 80 ? 46.110 125.213 28.585 1.00 46.59 ? 80 GLU A OE1 1 ATOM 609 O OE2 . GLU A 1 80 ? 44.648 123.657 28.258 1.00 46.29 ? 80 GLU A OE2 1 ATOM 610 N N . MET A 1 81 ? 47.458 118.583 26.640 1.00 37.95 ? 81 MET A N 1 ATOM 611 C CA . MET A 1 81 ? 47.474 117.152 27.014 1.00 37.13 ? 81 MET A CA 1 ATOM 612 C C . MET A 1 81 ? 48.829 116.614 27.492 1.00 36.47 ? 81 MET A C 1 ATOM 613 O O . MET A 1 81 ? 48.854 115.548 28.098 1.00 36.06 ? 81 MET A O 1 ATOM 614 C CB . MET A 1 81 ? 47.020 116.278 25.850 1.00 36.89 ? 81 MET A CB 1 ATOM 615 C CG . MET A 1 81 ? 47.947 116.333 24.655 1.00 36.37 ? 81 MET A CG 1 ATOM 616 S SD . MET A 1 81 ? 47.219 115.410 23.298 1.00 41.36 ? 81 MET A SD 1 ATOM 617 C CE . MET A 1 81 ? 47.592 113.740 23.900 1.00 34.42 ? 81 MET A CE 1 ATOM 618 N N . TRP A 1 82 ? 49.930 117.323 27.174 1.00 36.95 ? 82 TRP A N 1 ATOM 619 C CA . TRP A 1 82 ? 51.322 116.970 27.556 1.00 36.73 ? 82 TRP A CA 1 ATOM 620 C C . TRP A 1 82 ? 51.832 117.637 28.855 1.00 38.09 ? 82 TRP A C 1 ATOM 621 O O . TRP A 1 82 ? 52.833 117.185 29.512 1.00 37.75 ? 82 TRP A O 1 ATOM 622 C CB . TRP A 1 82 ? 52.283 117.252 26.376 1.00 36.84 ? 82 TRP A CB 1 ATOM 623 C CG . TRP A 1 82 ? 51.862 116.588 25.067 1.00 34.50 ? 82 TRP A CG 1 ATOM 624 C CD1 . TRP A 1 82 ? 51.381 117.200 23.944 1.00 34.27 ? 82 TRP A CD1 1 ATOM 625 C CD2 . TRP A 1 82 ? 51.839 115.176 24.788 1.00 35.59 ? 82 TRP A CD2 1 ATOM 626 N NE1 . TRP A 1 82 ? 51.086 116.264 22.972 1.00 34.85 ? 82 TRP A NE1 1 ATOM 627 C CE2 . TRP A 1 82 ? 51.369 115.014 23.461 1.00 35.55 ? 82 TRP A CE2 1 ATOM 628 C CE3 . TRP A 1 82 ? 52.233 114.033 25.505 1.00 34.50 ? 82 TRP A CE3 1 ATOM 629 C CZ2 . TRP A 1 82 ? 51.260 113.749 22.841 1.00 37.66 ? 82 TRP A CZ2 1 ATOM 630 C CZ3 . TRP A 1 82 ? 52.119 112.775 24.898 1.00 36.22 ? 82 TRP A CZ3 1 ATOM 631 C CH2 . TRP A 1 82 ? 51.639 112.648 23.562 1.00 35.44 ? 82 TRP A CH2 1 ATOM 632 N N . ASN A 1 83 ? 51.136 118.687 29.278 1.00 38.27 ? 83 ASN A N 1 ATOM 633 C CA . ASN A 1 83 ? 51.492 119.363 30.552 1.00 38.49 ? 83 ASN A CA 1 ATOM 634 C C . ASN A 1 83 ? 51.178 118.492 31.788 1.00 38.23 ? 83 ASN A C 1 ATOM 635 O O . ASN A 1 83 ? 50.266 117.690 31.759 1.00 38.25 ? 83 ASN A O 1 ATOM 636 C CB . ASN A 1 83 ? 50.796 120.720 30.614 1.00 38.85 ? 83 ASN A CB 1 ATOM 637 C CG . ASN A 1 83 ? 51.342 121.673 29.573 1.00 41.36 ? 83 ASN A CG 1 ATOM 638 O OD1 . ASN A 1 83 ? 52.508 121.534 29.168 1.00 40.64 ? 83 ASN A OD1 1 ATOM 639 N ND2 . ASN A 1 83 ? 50.526 122.639 29.124 1.00 40.05 ? 83 ASN A ND2 1 ATOM 640 N N . PRO A 1 84 ? 51.925 118.650 32.870 1.00 37.93 ? 84 PRO A N 1 ATOM 641 C CA . PRO A 1 84 ? 51.678 117.887 34.077 1.00 38.10 ? 84 PRO A CA 1 ATOM 642 C C . PRO A 1 84 ? 50.253 118.075 34.596 1.00 38.14 ? 84 PRO A C 1 ATOM 643 O O . PRO A 1 84 ? 49.713 119.158 34.501 1.00 37.26 ? 84 PRO A O 1 ATOM 644 C CB . PRO A 1 84 ? 52.675 118.472 35.070 1.00 38.92 ? 84 PRO A CB 1 ATOM 645 C CG . PRO A 1 84 ? 53.755 119.035 34.214 1.00 38.51 ? 84 PRO A CG 1 ATOM 646 C CD . PRO A 1 84 ? 53.055 119.579 33.013 1.00 38.41 ? 84 PRO A CD 1 ATOM 647 N N . ASN A 1 85 ? 49.659 117.004 35.104 1.00 37.90 ? 85 ASN A N 1 ATOM 648 C CA . ASN A 1 85 ? 48.281 117.021 35.593 1.00 38.88 ? 85 ASN A CA 1 ATOM 649 C C . ASN A 1 85 ? 48.281 116.662 37.069 1.00 38.35 ? 85 ASN A C 1 ATOM 650 O O . ASN A 1 85 ? 47.297 116.217 37.634 1.00 39.47 ? 85 ASN A O 1 ATOM 651 C CB . ASN A 1 85 ? 47.408 116.046 34.759 1.00 38.43 ? 85 ASN A CB 1 ATOM 652 C CG . ASN A 1 85 ? 47.937 114.594 34.810 1.00 39.20 ? 85 ASN A CG 1 ATOM 653 O OD1 . ASN A 1 85 ? 49.063 114.346 35.264 1.00 42.49 ? 85 ASN A OD1 1 ATOM 654 N ND2 . ASN A 1 85 ? 47.133 113.647 34.336 1.00 37.57 ? 85 ASN A ND2 1 ATOM 655 N N . THR A 1 86 ? 49.417 116.877 37.696 1.00 39.84 ? 86 THR A N 1 ATOM 656 C CA . THR A 1 86 ? 49.566 116.668 39.119 1.00 39.64 ? 86 THR A CA 1 ATOM 657 C C . THR A 1 86 ? 50.491 117.811 39.589 1.00 39.95 ? 86 THR A C 1 ATOM 658 O O . THR A 1 86 ? 51.305 118.301 38.778 1.00 40.14 ? 86 THR A O 1 ATOM 659 C CB . THR A 1 86 ? 50.173 115.270 39.223 1.00 40.34 ? 86 THR A CB 1 ATOM 660 O OG1 . THR A 1 86 ? 49.376 114.443 40.078 1.00 44.77 ? 86 THR A OG1 1 ATOM 661 C CG2 . THR A 1 86 ? 51.510 115.256 39.734 1.00 33.31 ? 86 THR A CG2 1 ATOM 662 N N A ASP A 1 87 ? 50.379 118.220 40.863 0.50 39.59 ? 87 ASP A N 1 ATOM 663 N N B ASP A 1 87 ? 50.368 118.237 40.842 0.50 39.70 ? 87 ASP A N 1 ATOM 664 C CA A ASP A 1 87 ? 51.257 119.263 41.447 0.50 39.97 ? 87 ASP A CA 1 ATOM 665 C CA B ASP A 1 87 ? 51.241 119.284 41.383 0.50 40.17 ? 87 ASP A CA 1 ATOM 666 C C A ASP A 1 87 ? 52.690 118.960 41.111 0.50 40.11 ? 87 ASP A C 1 ATOM 667 C C B ASP A 1 87 ? 52.695 118.967 41.170 0.50 40.23 ? 87 ASP A C 1 ATOM 668 O O A ASP A 1 87 ? 53.095 117.797 41.097 0.50 39.98 ? 87 ASP A O 1 ATOM 669 O O B ASP A 1 87 ? 53.110 117.808 41.265 0.50 40.05 ? 87 ASP A O 1 ATOM 670 C CB A ASP A 1 87 ? 51.222 119.348 42.995 0.50 39.54 ? 87 ASP A CB 1 ATOM 671 C CB B ASP A 1 87 ? 51.004 119.498 42.881 0.50 39.91 ? 87 ASP A CB 1 ATOM 672 C CG A ASP A 1 87 ? 49.833 119.245 43.583 0.50 39.18 ? 87 ASP A CG 1 ATOM 673 C CG B ASP A 1 87 ? 49.733 120.241 43.149 0.50 40.00 ? 87 ASP A CG 1 ATOM 674 O OD1 A ASP A 1 87 ? 49.355 120.246 44.142 0.50 38.17 ? 87 ASP A OD1 1 ATOM 675 O OD1 B ASP A 1 87 ? 49.815 121.423 43.519 0.50 39.42 ? 87 ASP A OD1 1 ATOM 676 O OD2 A ASP A 1 87 ? 49.161 118.200 43.591 0.50 41.49 ? 87 ASP A OD2 1 ATOM 677 O OD2 B ASP A 1 87 ? 48.607 119.751 42.964 0.50 40.14 ? 87 ASP A OD2 1 ATOM 678 N N . LEU A 1 88 ? 53.463 120.018 40.907 1.00 40.63 ? 88 LEU A N 1 ATOM 679 C CA . LEU A 1 88 ? 54.877 119.899 40.693 1.00 41.28 ? 88 LEU A CA 1 ATOM 680 C C . LEU A 1 88 ? 55.548 119.984 42.045 1.00 42.27 ? 88 LEU A C 1 ATOM 681 O O . LEU A 1 88 ? 55.142 120.765 42.932 1.00 42.64 ? 88 LEU A O 1 ATOM 682 C CB . LEU A 1 88 ? 55.391 121.026 39.779 1.00 41.08 ? 88 LEU A CB 1 ATOM 683 C CG . LEU A 1 88 ? 54.747 121.200 38.383 1.00 39.72 ? 88 LEU A CG 1 ATOM 684 C CD1 . LEU A 1 88 ? 55.479 122.247 37.621 1.00 37.39 ? 88 LEU A CD1 1 ATOM 685 C CD2 . LEU A 1 88 ? 54.793 119.903 37.584 1.00 37.46 ? 88 LEU A CD2 1 ATOM 686 N N . SER A 1 89 ? 56.608 119.212 42.200 1.00 41.88 ? 89 SER A N 1 ATOM 687 C CA . SER A 1 89 ? 57.318 119.232 43.453 1.00 41.86 ? 89 SER A CA 1 ATOM 688 C C . SER A 1 89 ? 58.662 118.541 43.235 1.00 42.12 ? 89 SER A C 1 ATOM 689 O O . SER A 1 89 ? 58.758 117.651 42.404 1.00 41.55 ? 89 SER A O 1 ATOM 690 C CB . SER A 1 89 ? 56.477 118.496 44.500 1.00 40.66 ? 89 SER A CB 1 ATOM 691 O OG . SER A 1 89 ? 57.220 118.334 45.690 1.00 42.72 ? 89 SER A OG 1 ATOM 692 N N . GLU A 1 90 ? 59.693 118.958 43.953 1.00 42.60 ? 90 GLU A N 1 ATOM 693 C CA . GLU A 1 90 ? 60.939 118.181 43.968 1.00 43.97 ? 90 GLU A CA 1 ATOM 694 C C . GLU A 1 90 ? 60.722 116.818 44.599 1.00 43.45 ? 90 GLU A C 1 ATOM 695 O O . GLU A 1 90 ? 61.532 115.903 44.427 1.00 43.50 ? 90 GLU A O 1 ATOM 696 C CB . GLU A 1 90 ? 62.023 118.892 44.754 1.00 44.45 ? 90 GLU A CB 1 ATOM 697 C CG . GLU A 1 90 ? 62.503 120.140 44.063 1.00 45.86 ? 90 GLU A CG 1 ATOM 698 C CD . GLU A 1 90 ? 63.709 120.696 44.767 1.00 48.69 ? 90 GLU A CD 1 ATOM 699 O OE1 . GLU A 1 90 ? 63.534 121.463 45.738 1.00 53.77 ? 90 GLU A OE1 1 ATOM 700 O OE2 . GLU A 1 90 ? 64.829 120.365 44.350 1.00 51.03 ? 90 GLU A OE2 1 ATOM 701 N N . ASP A 1 91 ? 59.610 116.690 45.307 1.00 42.15 ? 91 ASP A N 1 ATOM 702 C CA . ASP A 1 91 ? 59.266 115.450 45.964 1.00 42.46 ? 91 ASP A CA 1 ATOM 703 C C . ASP A 1 91 ? 58.356 114.737 44.960 1.00 40.87 ? 91 ASP A C 1 ATOM 704 O O . ASP A 1 91 ? 57.128 114.813 45.018 1.00 39.27 ? 91 ASP A O 1 ATOM 705 C CB . ASP A 1 91 ? 58.641 115.751 47.342 1.00 42.56 ? 91 ASP A CB 1 ATOM 706 C CG . ASP A 1 91 ? 58.100 114.536 48.027 1.00 47.01 ? 91 ASP A CG 1 ATOM 707 O OD1 . ASP A 1 91 ? 58.328 113.393 47.557 1.00 48.58 ? 91 ASP A OD1 1 ATOM 708 O OD2 . ASP A 1 91 ? 57.408 114.637 49.070 1.00 50.75 ? 91 ASP A OD2 1 ATOM 709 N N . CYS A 1 92 ? 59.013 114.070 44.004 1.00 39.92 ? 92 CYS A N 1 ATOM 710 C CA . CYS A 1 92 ? 58.339 113.513 42.839 1.00 38.57 ? 92 CYS A CA 1 ATOM 711 C C . CYS A 1 92 ? 58.785 112.041 42.493 1.00 38.81 ? 92 CYS A C 1 ATOM 712 O O . CYS A 1 92 ? 58.270 111.447 41.543 1.00 38.04 ? 92 CYS A O 1 ATOM 713 C CB . CYS A 1 92 ? 58.570 114.434 41.653 1.00 37.66 ? 92 CYS A CB 1 ATOM 714 S SG . CYS A 1 92 ? 60.304 114.519 41.064 1.00 37.69 ? 92 CYS A SG 1 ATOM 715 N N . LEU A 1 93 ? 59.707 111.472 43.270 1.00 37.45 ? 93 LEU A N 1 ATOM 716 C CA . LEU A 1 93 ? 60.237 110.104 42.993 1.00 37.57 ? 93 LEU A CA 1 ATOM 717 C C . LEU A 1 93 ? 59.263 109.002 43.372 1.00 37.73 ? 93 LEU A C 1 ATOM 718 O O . LEU A 1 93 ? 59.408 108.310 44.399 1.00 39.14 ? 93 LEU A O 1 ATOM 719 C CB . LEU A 1 93 ? 61.641 109.914 43.613 1.00 36.76 ? 93 LEU A CB 1 ATOM 720 C CG . LEU A 1 93 ? 62.637 110.911 43.006 1.00 35.35 ? 93 LEU A CG 1 ATOM 721 C CD1 . LEU A 1 93 ? 64.090 110.649 43.381 1.00 32.36 ? 93 LEU A CD1 1 ATOM 722 C CD2 . LEU A 1 93 ? 62.457 110.991 41.427 1.00 34.38 ? 93 LEU A CD2 1 ATOM 723 N N . TYR A 1 94 ? 58.258 108.844 42.519 1.00 37.16 ? 94 TYR A N 1 ATOM 724 C CA . TYR A 1 94 ? 57.152 107.890 42.738 1.00 37.35 ? 94 TYR A CA 1 ATOM 725 C C . TYR A 1 94 ? 56.896 107.075 41.451 1.00 37.41 ? 94 TYR A C 1 ATOM 726 O O . TYR A 1 94 ? 57.252 107.490 40.326 1.00 35.93 ? 94 TYR A O 1 ATOM 727 C CB . TYR A 1 94 ? 55.841 108.625 43.171 1.00 37.18 ? 94 TYR A CB 1 ATOM 728 C CG . TYR A 1 94 ? 56.032 109.411 44.488 1.00 37.03 ? 94 TYR A CG 1 ATOM 729 C CD1 . TYR A 1 94 ? 56.546 110.721 44.479 1.00 35.14 ? 94 TYR A CD1 1 ATOM 730 C CD2 . TYR A 1 94 ? 55.744 108.827 45.713 1.00 35.64 ? 94 TYR A CD2 1 ATOM 731 C CE1 . TYR A 1 94 ? 56.771 111.427 45.644 1.00 36.72 ? 94 TYR A CE1 1 ATOM 732 C CE2 . TYR A 1 94 ? 55.967 109.527 46.910 1.00 36.96 ? 94 TYR A CE2 1 ATOM 733 C CZ . TYR A 1 94 ? 56.481 110.823 46.861 1.00 39.61 ? 94 TYR A CZ 1 ATOM 734 O OH . TYR A 1 94 ? 56.738 111.521 48.022 1.00 42.44 ? 94 TYR A OH 1 ATOM 735 N N . LEU A 1 95 ? 56.281 105.921 41.652 1.00 37.02 ? 95 LEU A N 1 ATOM 736 C CA . LEU A 1 95 ? 55.945 105.059 40.571 1.00 37.50 ? 95 LEU A CA 1 ATOM 737 C C . LEU A 1 95 ? 54.517 104.506 40.755 1.00 37.96 ? 95 LEU A C 1 ATOM 738 O O . LEU A 1 95 ? 53.934 104.557 41.873 1.00 37.14 ? 95 LEU A O 1 ATOM 739 C CB . LEU A 1 95 ? 57.019 103.973 40.410 1.00 36.84 ? 95 LEU A CB 1 ATOM 740 C CG . LEU A 1 95 ? 57.285 102.947 41.527 1.00 36.99 ? 95 LEU A CG 1 ATOM 741 C CD1 . LEU A 1 95 ? 56.139 101.913 41.675 1.00 36.60 ? 95 LEU A CD1 1 ATOM 742 C CD2 . LEU A 1 95 ? 58.635 102.227 41.254 1.00 35.48 ? 95 LEU A CD2 1 ATOM 743 N N . ASN A 1 96 ? 53.991 103.988 39.645 1.00 37.08 ? 96 ASN A N 1 ATOM 744 C CA . ASN A 1 96 ? 52.661 103.421 39.527 1.00 37.66 ? 96 ASN A CA 1 ATOM 745 C C . ASN A 1 96 ? 52.728 101.957 39.059 1.00 37.57 ? 96 ASN A C 1 ATOM 746 O O . ASN A 1 96 ? 53.591 101.594 38.225 1.00 35.57 ? 96 ASN A O 1 ATOM 747 C CB . ASN A 1 96 ? 51.863 104.194 38.476 1.00 37.92 ? 96 ASN A CB 1 ATOM 748 C CG . ASN A 1 96 ? 52.035 105.703 38.611 1.00 41.62 ? 96 ASN A CG 1 ATOM 749 O OD1 . ASN A 1 96 ? 51.748 106.262 39.674 1.00 40.65 ? 96 ASN A OD1 1 ATOM 750 N ND2 . ASN A 1 96 ? 52.542 106.366 37.537 1.00 36.25 ? 96 ASN A ND2 1 ATOM 751 N N . VAL A 1 97 ? 51.820 101.130 39.591 1.00 37.58 ? 97 VAL A N 1 ATOM 752 C CA . VAL A 1 97 ? 51.707 99.720 39.170 1.00 37.47 ? 97 VAL A CA 1 ATOM 753 C C . VAL A 1 97 ? 50.260 99.376 38.829 1.00 38.64 ? 97 VAL A C 1 ATOM 754 O O . VAL A 1 97 ? 49.334 99.648 39.636 1.00 38.34 ? 97 VAL A O 1 ATOM 755 C CB . VAL A 1 97 ? 52.272 98.758 40.209 1.00 37.16 ? 97 VAL A CB 1 ATOM 756 C CG1 . VAL A 1 97 ? 52.321 97.347 39.657 1.00 36.82 ? 97 VAL A CG1 1 ATOM 757 C CG2 . VAL A 1 97 ? 53.655 99.151 40.608 1.00 37.81 ? 97 VAL A CG2 1 ATOM 758 N N . TRP A 1 98 ? 50.039 98.859 37.610 1.00 37.99 ? 98 TRP A N 1 ATOM 759 C CA . TRP A 1 98 ? 48.707 98.354 37.257 1.00 38.63 ? 98 TRP A CA 1 ATOM 760 C C . TRP A 1 98 ? 48.845 96.870 37.065 1.00 39.87 ? 98 TRP A C 1 ATOM 761 O O . TRP A 1 98 ? 49.721 96.398 36.320 1.00 40.10 ? 98 TRP A O 1 ATOM 762 C CB . TRP A 1 98 ? 48.141 98.950 35.987 1.00 36.69 ? 98 TRP A CB 1 ATOM 763 C CG . TRP A 1 98 ? 47.769 100.397 36.029 1.00 37.28 ? 98 TRP A CG 1 ATOM 764 C CD1 . TRP A 1 98 ? 46.512 100.921 36.261 1.00 35.59 ? 98 TRP A CD1 1 ATOM 765 C CD2 . TRP A 1 98 ? 48.628 101.529 35.756 1.00 35.71 ? 98 TRP A CD2 1 ATOM 766 N NE1 . TRP A 1 98 ? 46.556 102.292 36.177 1.00 37.34 ? 98 TRP A NE1 1 ATOM 767 C CE2 . TRP A 1 98 ? 47.838 102.695 35.876 1.00 36.96 ? 98 TRP A CE2 1 ATOM 768 C CE3 . TRP A 1 98 ? 49.985 101.671 35.418 1.00 34.56 ? 98 TRP A CE3 1 ATOM 769 C CZ2 . TRP A 1 98 ? 48.362 103.999 35.663 1.00 37.01 ? 98 TRP A CZ2 1 ATOM 770 C CZ3 . TRP A 1 98 ? 50.507 102.954 35.230 1.00 36.19 ? 98 TRP A CZ3 1 ATOM 771 C CH2 . TRP A 1 98 ? 49.696 104.102 35.340 1.00 33.42 ? 98 TRP A CH2 1 ATOM 772 N N . ILE A 1 99 ? 47.998 96.138 37.776 1.00 41.39 ? 99 ILE A N 1 ATOM 773 C CA . ILE A 1 99 ? 48.000 94.704 37.727 1.00 43.29 ? 99 ILE A CA 1 ATOM 774 C C . ILE A 1 99 ? 46.615 94.178 37.347 1.00 44.30 ? 99 ILE A C 1 ATOM 775 O O . ILE A 1 99 ? 45.583 94.763 37.712 1.00 44.90 ? 99 ILE A O 1 ATOM 776 C CB . ILE A 1 99 ? 48.582 94.058 39.031 1.00 43.38 ? 99 ILE A CB 1 ATOM 777 C CG1 . ILE A 1 99 ? 47.572 94.051 40.187 1.00 44.12 ? 99 ILE A CG1 1 ATOM 778 C CG2 . ILE A 1 99 ? 49.910 94.719 39.414 1.00 43.14 ? 99 ILE A CG2 1 ATOM 779 C CD1 . ILE A 1 99 ? 47.995 93.170 41.414 1.00 45.05 ? 99 ILE A CD1 1 ATOM 780 N N . PRO A 1 100 ? 46.591 93.078 36.597 1.00 45.09 ? 100 PRO A N 1 ATOM 781 C CA . PRO A 1 100 ? 45.324 92.450 36.235 1.00 46.10 ? 100 PRO A CA 1 ATOM 782 C C . PRO A 1 100 ? 44.615 91.867 37.490 1.00 47.25 ? 100 PRO A C 1 ATOM 783 O O . PRO A 1 100 ? 45.248 91.622 38.516 1.00 45.36 ? 100 PRO A O 1 ATOM 784 C CB . PRO A 1 100 ? 45.730 91.351 35.244 1.00 45.91 ? 100 PRO A CB 1 ATOM 785 C CG . PRO A 1 100 ? 47.203 91.541 34.980 1.00 45.83 ? 100 PRO A CG 1 ATOM 786 C CD . PRO A 1 100 ? 47.759 92.349 36.079 1.00 44.91 ? 100 PRO A CD 1 ATOM 787 N N . ALA A 1 101 ? 43.296 91.705 37.395 1.00 49.21 ? 101 ALA A N 1 ATOM 788 C CA . ALA A 1 101 ? 42.505 91.134 38.463 1.00 51.06 ? 101 ALA A CA 1 ATOM 789 C C . ALA A 1 101 ? 41.716 90.031 37.811 1.00 51.87 ? 101 ALA A C 1 ATOM 790 O O . ALA A 1 101 ? 41.080 90.263 36.792 1.00 53.20 ? 101 ALA A O 1 ATOM 791 C CB . ALA A 1 101 ? 41.567 92.176 39.071 1.00 51.88 ? 101 ALA A CB 1 ATOM 792 N N . PRO A 1 102 ? 41.779 88.818 38.349 1.00 52.63 ? 102 PRO A N 1 ATOM 793 C CA . PRO A 1 102 ? 42.530 88.527 39.559 1.00 52.43 ? 102 PRO A CA 1 ATOM 794 C C . PRO A 1 102 ? 44.033 88.543 39.363 1.00 52.04 ? 102 PRO A C 1 ATOM 795 O O . PRO A 1 102 ? 44.527 88.393 38.245 1.00 51.45 ? 102 PRO A O 1 ATOM 796 C CB . PRO A 1 102 ? 42.049 87.121 39.955 1.00 53.01 ? 102 PRO A CB 1 ATOM 797 C CG . PRO A 1 102 ? 41.507 86.504 38.698 1.00 53.32 ? 102 PRO A CG 1 ATOM 798 C CD . PRO A 1 102 ? 41.101 87.629 37.790 1.00 53.33 ? 102 PRO A CD 1 ATOM 799 N N . LYS A 1 103 ? 44.720 88.755 40.479 1.00 52.02 ? 103 LYS A N 1 ATOM 800 C CA . LYS A 1 103 ? 46.152 88.788 40.579 1.00 52.14 ? 103 LYS A CA 1 ATOM 801 C C . LYS A 1 103 ? 46.778 87.735 39.674 1.00 51.72 ? 103 LYS A C 1 ATOM 802 O O . LYS A 1 103 ? 46.398 86.577 39.748 1.00 51.69 ? 103 LYS A O 1 ATOM 803 C CB . LYS A 1 103 ? 46.538 88.527 42.017 1.00 52.49 ? 103 LYS A CB 1 ATOM 804 C CG . LYS A 1 103 ? 47.996 88.757 42.337 1.00 54.69 ? 103 LYS A CG 1 ATOM 805 C CD . LYS A 1 103 ? 48.120 89.024 43.836 1.00 58.02 ? 103 LYS A CD 1 ATOM 806 C CE . LYS A 1 103 ? 49.538 89.341 44.260 1.00 59.21 ? 103 LYS A CE 1 ATOM 807 N NZ . LYS A 1 103 ? 50.318 88.080 44.372 1.00 61.95 ? 103 LYS A NZ 1 ATOM 808 N N . PRO A 1 104 ? 47.725 88.143 38.820 1.00 50.78 ? 104 PRO A N 1 ATOM 809 C CA . PRO A 1 104 ? 48.361 87.224 37.886 1.00 50.22 ? 104 PRO A CA 1 ATOM 810 C C . PRO A 1 104 ? 49.337 86.373 38.664 1.00 49.88 ? 104 PRO A C 1 ATOM 811 O O . PRO A 1 104 ? 49.676 86.742 39.794 1.00 49.55 ? 104 PRO A O 1 ATOM 812 C CB . PRO A 1 104 ? 49.100 88.169 36.938 1.00 49.88 ? 104 PRO A CB 1 ATOM 813 C CG . PRO A 1 104 ? 49.498 89.283 37.837 1.00 50.35 ? 104 PRO A CG 1 ATOM 814 C CD . PRO A 1 104 ? 48.280 89.507 38.709 1.00 50.04 ? 104 PRO A CD 1 ATOM 815 N N . LYS A 1 105 ? 49.778 85.250 38.095 1.00 49.65 ? 105 LYS A N 1 ATOM 816 C CA . LYS A 1 105 ? 50.742 84.393 38.790 1.00 50.62 ? 105 LYS A CA 1 ATOM 817 C C . LYS A 1 105 ? 52.216 84.767 38.544 1.00 50.22 ? 105 LYS A C 1 ATOM 818 O O . LYS A 1 105 ? 53.022 84.802 39.493 1.00 52.13 ? 105 LYS A O 1 ATOM 819 C CB . LYS A 1 105 ? 50.504 82.906 38.473 1.00 51.42 ? 105 LYS A CB 1 ATOM 820 C CG . LYS A 1 105 ? 49.196 82.341 39.043 1.00 53.76 ? 105 LYS A CG 1 ATOM 821 C CD . LYS A 1 105 ? 49.403 81.405 40.211 1.00 56.56 ? 105 LYS A CD 1 ATOM 822 C CE . LYS A 1 105 ? 48.059 81.068 40.889 1.00 56.27 ? 105 LYS A CE 1 ATOM 823 N NZ . LYS A 1 105 ? 46.930 81.441 39.985 1.00 53.45 ? 105 LYS A NZ 1 ATOM 824 N N . ASN A 1 106 ? 52.579 85.027 37.292 1.00 47.82 ? 106 ASN A N 1 ATOM 825 C CA . ASN A 1 106 ? 53.959 85.379 36.949 1.00 46.32 ? 106 ASN A CA 1 ATOM 826 C C . ASN A 1 106 ? 53.873 86.239 35.654 1.00 44.54 ? 106 ASN A C 1 ATOM 827 O O . ASN A 1 106 ? 54.310 85.836 34.582 1.00 43.95 ? 106 ASN A O 1 ATOM 828 C CB . ASN A 1 106 ? 54.686 84.061 36.708 1.00 46.45 ? 106 ASN A CB 1 ATOM 829 C CG . ASN A 1 106 ? 56.175 84.117 36.939 1.00 50.66 ? 106 ASN A CG 1 ATOM 830 O OD1 . ASN A 1 106 ? 56.714 84.931 37.713 1.00 50.78 ? 106 ASN A OD1 1 ATOM 831 N ND2 . ASN A 1 106 ? 56.865 83.191 36.245 1.00 55.66 ? 106 ASN A ND2 1 ATOM 832 N N . ALA A 1 107 ? 53.237 87.400 35.747 1.00 42.67 ? 107 ALA A N 1 ATOM 833 C CA . ALA A 1 107 ? 52.928 88.193 34.555 1.00 41.09 ? 107 ALA A CA 1 ATOM 834 C C . ALA A 1 107 ? 54.169 88.900 34.050 1.00 40.41 ? 107 ALA A C 1 ATOM 835 O O . ALA A 1 107 ? 55.037 89.302 34.839 1.00 40.68 ? 107 ALA A O 1 ATOM 836 C CB . ALA A 1 107 ? 51.819 89.191 34.850 1.00 40.81 ? 107 ALA A CB 1 ATOM 837 N N . THR A 1 108 ? 54.263 89.027 32.734 1.00 39.43 ? 108 THR A N 1 ATOM 838 C CA . THR A 1 108 ? 55.297 89.832 32.107 1.00 38.50 ? 108 THR A CA 1 ATOM 839 C C . THR A 1 108 ? 55.060 91.319 32.483 1.00 37.89 ? 108 THR A C 1 ATOM 840 O O . THR A 1 108 ? 53.899 91.804 32.554 1.00 36.92 ? 108 THR A O 1 ATOM 841 C CB . THR A 1 108 ? 55.242 89.617 30.562 1.00 39.24 ? 108 THR A CB 1 ATOM 842 O OG1 . THR A 1 108 ? 56.004 88.455 30.210 1.00 40.97 ? 108 THR A OG1 1 ATOM 843 C CG2 . THR A 1 108 ? 55.973 90.751 29.808 1.00 38.81 ? 108 THR A CG2 1 ATOM 844 N N . VAL A 1 109 ? 56.166 92.033 32.688 1.00 38.01 ? 109 VAL A N 1 ATOM 845 C CA . VAL A 1 109 ? 56.127 93.424 33.152 1.00 38.16 ? 109 VAL A CA 1 ATOM 846 C C . VAL A 1 109 ? 56.591 94.400 32.056 1.00 37.72 ? 109 VAL A C 1 ATOM 847 O O . VAL A 1 109 ? 57.641 94.223 31.474 1.00 37.98 ? 109 VAL A O 1 ATOM 848 C CB . VAL A 1 109 ? 56.984 93.603 34.425 1.00 36.68 ? 109 VAL A CB 1 ATOM 849 C CG1 . VAL A 1 109 ? 57.000 95.080 34.902 1.00 36.73 ? 109 VAL A CG1 1 ATOM 850 C CG2 . VAL A 1 109 ? 56.506 92.630 35.563 1.00 38.34 ? 109 VAL A CG2 1 ATOM 851 N N . LEU A 1 110 ? 55.782 95.428 31.836 1.00 37.56 ? 110 LEU A N 1 ATOM 852 C CA . LEU A 1 110 ? 56.005 96.525 30.880 1.00 37.10 ? 110 LEU A CA 1 ATOM 853 C C . LEU A 1 110 ? 56.290 97.835 31.654 1.00 35.83 ? 110 LEU A C 1 ATOM 854 O O . LEU A 1 110 ? 55.437 98.310 32.396 1.00 34.91 ? 110 LEU A O 1 ATOM 855 C CB . LEU A 1 110 ? 54.756 96.684 30.012 1.00 36.53 ? 110 LEU A CB 1 ATOM 856 C CG . LEU A 1 110 ? 54.848 95.931 28.685 1.00 40.83 ? 110 LEU A CG 1 ATOM 857 C CD1 . LEU A 1 110 ? 55.070 94.431 28.889 1.00 42.41 ? 110 LEU A CD1 1 ATOM 858 C CD2 . LEU A 1 110 ? 53.603 96.169 27.845 1.00 41.70 ? 110 LEU A CD2 1 ATOM 859 N N . ILE A 1 111 ? 57.501 98.384 31.499 1.00 34.95 ? 111 ILE A N 1 ATOM 860 C CA . ILE A 1 111 ? 57.882 99.564 32.253 1.00 33.60 ? 111 ILE A CA 1 ATOM 861 C C . ILE A 1 111 ? 58.025 100.736 31.346 1.00 32.64 ? 111 ILE A C 1 ATOM 862 O O . ILE A 1 111 ? 58.931 100.733 30.481 1.00 32.12 ? 111 ILE A O 1 ATOM 863 C CB . ILE A 1 111 ? 59.184 99.400 33.018 1.00 33.74 ? 111 ILE A CB 1 ATOM 864 C CG1 . ILE A 1 111 ? 59.153 98.191 33.976 1.00 34.42 ? 111 ILE A CG1 1 ATOM 865 C CG2 . ILE A 1 111 ? 59.442 100.701 33.744 1.00 30.63 ? 111 ILE A CG2 1 ATOM 866 C CD1 . ILE A 1 111 ? 60.484 97.991 34.727 1.00 34.04 ? 111 ILE A CD1 1 ATOM 867 N N . TRP A 1 112 ? 57.147 101.728 31.574 1.00 31.00 ? 112 TRP A N 1 ATOM 868 C CA . TRP A 1 112 ? 57.063 102.929 30.738 1.00 31.60 ? 112 TRP A CA 1 ATOM 869 C C . TRP A 1 112 ? 57.975 104.041 31.213 1.00 31.20 ? 112 TRP A C 1 ATOM 870 O O . TRP A 1 112 ? 57.980 104.415 32.409 1.00 30.38 ? 112 TRP A O 1 ATOM 871 C CB . TRP A 1 112 ? 55.611 103.440 30.626 1.00 30.79 ? 112 TRP A CB 1 ATOM 872 C CG . TRP A 1 112 ? 55.436 104.716 29.801 1.00 30.17 ? 112 TRP A CG 1 ATOM 873 C CD1 . TRP A 1 112 ? 55.164 105.995 30.278 1.00 29.35 ? 112 TRP A CD1 1 ATOM 874 C CD2 . TRP A 1 112 ? 55.511 104.842 28.366 1.00 30.55 ? 112 TRP A CD2 1 ATOM 875 N NE1 . TRP A 1 112 ? 55.098 106.885 29.232 1.00 28.70 ? 112 TRP A NE1 1 ATOM 876 C CE2 . TRP A 1 112 ? 55.282 106.210 28.049 1.00 31.44 ? 112 TRP A CE2 1 ATOM 877 C CE3 . TRP A 1 112 ? 55.743 103.932 27.309 1.00 31.46 ? 112 TRP A CE3 1 ATOM 878 C CZ2 . TRP A 1 112 ? 55.252 106.681 26.730 1.00 29.71 ? 112 TRP A CZ2 1 ATOM 879 C CZ3 . TRP A 1 112 ? 55.712 104.398 26.011 1.00 27.74 ? 112 TRP A CZ3 1 ATOM 880 C CH2 . TRP A 1 112 ? 55.486 105.757 25.726 1.00 28.58 ? 112 TRP A CH2 1 ATOM 881 N N . ILE A 1 113 ? 58.740 104.566 30.266 1.00 30.51 ? 113 ILE A N 1 ATOM 882 C CA . ILE A 1 113 ? 59.533 105.773 30.488 1.00 30.32 ? 113 ILE A CA 1 ATOM 883 C C . ILE A 1 113 ? 59.066 106.874 29.552 1.00 30.82 ? 113 ILE A C 1 ATOM 884 O O . ILE A 1 113 ? 59.277 106.805 28.309 1.00 30.93 ? 113 ILE A O 1 ATOM 885 C CB . ILE A 1 113 ? 61.081 105.489 30.304 1.00 30.19 ? 113 ILE A CB 1 ATOM 886 C CG1 . ILE A 1 113 ? 61.542 104.252 31.116 1.00 28.75 ? 113 ILE A CG1 1 ATOM 887 C CG2 . ILE A 1 113 ? 61.902 106.769 30.665 1.00 29.22 ? 113 ILE A CG2 1 ATOM 888 C CD1 . ILE A 1 113 ? 63.104 103.880 30.928 1.00 29.52 ? 113 ILE A CD1 1 ATOM 889 N N . TYR A 1 114 ? 58.457 107.919 30.127 1.00 31.94 ? 114 TYR A N 1 ATOM 890 C CA . TYR A 1 114 ? 57.930 109.064 29.316 1.00 31.22 ? 114 TYR A CA 1 ATOM 891 C C . TYR A 1 114 ? 59.034 109.889 28.643 1.00 30.90 ? 114 TYR A C 1 ATOM 892 O O . TYR A 1 114 ? 60.151 109.992 29.148 1.00 31.71 ? 114 TYR A O 1 ATOM 893 C CB . TYR A 1 114 ? 57.007 109.979 30.169 1.00 30.94 ? 114 TYR A CB 1 ATOM 894 C CG . TYR A 1 114 ? 57.659 110.618 31.421 1.00 31.67 ? 114 TYR A CG 1 ATOM 895 C CD1 . TYR A 1 114 ? 58.561 111.685 31.330 1.00 29.75 ? 114 TYR A CD1 1 ATOM 896 C CD2 . TYR A 1 114 ? 57.316 110.188 32.675 1.00 29.07 ? 114 TYR A CD2 1 ATOM 897 C CE1 . TYR A 1 114 ? 59.121 112.258 32.486 1.00 28.08 ? 114 TYR A CE1 1 ATOM 898 C CE2 . TYR A 1 114 ? 57.901 110.719 33.818 1.00 28.76 ? 114 TYR A CE2 1 ATOM 899 C CZ . TYR A 1 114 ? 58.753 111.752 33.733 1.00 29.22 ? 114 TYR A CZ 1 ATOM 900 O OH . TYR A 1 114 ? 59.292 112.230 34.920 1.00 32.39 ? 114 TYR A OH 1 ATOM 901 N N . GLY A 1 115 ? 58.698 110.522 27.537 1.00 30.81 ? 115 GLY A N 1 ATOM 902 C CA . GLY A 1 115 ? 59.521 111.583 26.991 1.00 31.46 ? 115 GLY A CA 1 ATOM 903 C C . GLY A 1 115 ? 59.081 113.001 27.423 1.00 32.60 ? 115 GLY A C 1 ATOM 904 O O . GLY A 1 115 ? 58.324 113.194 28.394 1.00 31.25 ? 115 GLY A O 1 ATOM 905 N N . GLY A 1 116 ? 59.609 113.984 26.708 1.00 32.20 ? 116 GLY A N 1 ATOM 906 C CA . GLY A 1 116 ? 59.522 115.373 27.132 1.00 33.50 ? 116 GLY A CA 1 ATOM 907 C C . GLY A 1 116 ? 60.854 116.095 26.989 1.00 34.51 ? 116 GLY A C 1 ATOM 908 O O . GLY A 1 116 ? 61.128 117.069 27.711 1.00 34.43 ? 116 GLY A O 1 ATOM 909 N N . GLY A 1 117 ? 61.705 115.592 26.085 1.00 33.69 ? 117 GLY A N 1 ATOM 910 C CA . GLY A 1 117 ? 63.025 116.182 25.848 1.00 34.70 ? 117 GLY A CA 1 ATOM 911 C C . GLY A 1 117 ? 63.977 116.197 27.047 1.00 34.29 ? 117 GLY A C 1 ATOM 912 O O . GLY A 1 117 ? 64.884 116.967 27.051 1.00 35.31 ? 117 GLY A O 1 ATOM 913 N N . PHE A 1 118 ? 63.788 115.320 28.031 1.00 34.11 ? 118 PHE A N 1 ATOM 914 C CA . PHE A 1 118 ? 64.544 115.346 29.306 1.00 34.62 ? 118 PHE A CA 1 ATOM 915 C C . PHE A 1 118 ? 64.335 116.637 30.145 1.00 34.95 ? 118 PHE A C 1 ATOM 916 O O . PHE A 1 118 ? 65.057 116.854 31.102 1.00 34.06 ? 118 PHE A O 1 ATOM 917 C CB . PHE A 1 118 ? 66.081 115.061 29.138 1.00 33.89 ? 118 PHE A CB 1 ATOM 918 C CG . PHE A 1 118 ? 66.407 113.704 28.537 1.00 33.04 ? 118 PHE A CG 1 ATOM 919 C CD1 . PHE A 1 118 ? 66.325 112.549 29.314 1.00 30.43 ? 118 PHE A CD1 1 ATOM 920 C CD2 . PHE A 1 118 ? 66.819 113.608 27.185 1.00 30.61 ? 118 PHE A CD2 1 ATOM 921 C CE1 . PHE A 1 118 ? 66.633 111.301 28.766 1.00 34.81 ? 118 PHE A CE1 1 ATOM 922 C CE2 . PHE A 1 118 ? 67.168 112.365 26.632 1.00 30.98 ? 118 PHE A CE2 1 ATOM 923 C CZ . PHE A 1 118 ? 67.037 111.205 27.419 1.00 30.62 ? 118 PHE A CZ 1 ATOM 924 N N . GLN A 1 119 ? 63.380 117.490 29.765 1.00 35.37 ? 119 GLN A N 1 ATOM 925 C CA . GLN A 1 119 ? 63.117 118.759 30.487 1.00 35.84 ? 119 GLN A CA 1 ATOM 926 C C . GLN A 1 119 ? 61.713 118.727 31.094 1.00 35.97 ? 119 GLN A C 1 ATOM 927 O O . GLN A 1 119 ? 61.424 119.460 32.037 1.00 36.31 ? 119 GLN A O 1 ATOM 928 C CB . GLN A 1 119 ? 63.213 119.998 29.554 1.00 35.81 ? 119 GLN A CB 1 ATOM 929 C CG . GLN A 1 119 ? 64.386 120.074 28.520 1.00 35.09 ? 119 GLN A CG 1 ATOM 930 C CD . GLN A 1 119 ? 65.740 119.744 29.138 1.00 40.10 ? 119 GLN A CD 1 ATOM 931 O OE1 . GLN A 1 119 ? 66.382 118.730 28.770 1.00 41.43 ? 119 GLN A OE1 1 ATOM 932 N NE2 . GLN A 1 119 ? 66.148 120.535 30.123 1.00 38.12 ? 119 GLN A NE2 1 ATOM 933 N N . THR A 1 120 ? 60.831 117.916 30.516 1.00 35.77 ? 120 THR A N 1 ATOM 934 C CA . THR A 1 120 ? 59.451 117.825 30.947 1.00 35.99 ? 120 THR A CA 1 ATOM 935 C C . THR A 1 120 ? 58.933 116.380 30.967 1.00 35.45 ? 120 THR A C 1 ATOM 936 O O . THR A 1 120 ? 59.625 115.449 30.536 1.00 35.46 ? 120 THR A O 1 ATOM 937 C CB . THR A 1 120 ? 58.512 118.639 30.016 1.00 36.82 ? 120 THR A CB 1 ATOM 938 O OG1 . THR A 1 120 ? 58.523 118.039 28.716 1.00 36.37 ? 120 THR A OG1 1 ATOM 939 C CG2 . THR A 1 120 ? 58.981 120.141 29.799 1.00 34.87 ? 120 THR A CG2 1 ATOM 940 N N . GLY A 1 121 ? 57.713 116.231 31.483 1.00 33.81 ? 121 GLY A N 1 ATOM 941 C CA . GLY A 1 121 ? 56.965 115.016 31.410 1.00 33.62 ? 121 GLY A CA 1 ATOM 942 C C . GLY A 1 121 ? 56.577 114.433 32.738 1.00 33.25 ? 121 GLY A C 1 ATOM 943 O O . GLY A 1 121 ? 57.119 114.780 33.797 1.00 33.29 ? 121 GLY A O 1 ATOM 944 N N . THR A 1 122 ? 55.613 113.538 32.693 1.00 32.32 ? 122 THR A N 1 ATOM 945 C CA . THR A 1 122 ? 55.225 112.897 33.920 1.00 32.68 ? 122 THR A CA 1 ATOM 946 C C . THR A 1 122 ? 54.508 111.574 33.614 1.00 32.47 ? 122 THR A C 1 ATOM 947 O O . THR A 1 122 ? 53.919 111.425 32.522 1.00 31.75 ? 122 THR A O 1 ATOM 948 C CB . THR A 1 122 ? 54.365 113.902 34.800 1.00 33.47 ? 122 THR A CB 1 ATOM 949 O OG1 . THR A 1 122 ? 53.998 113.268 36.025 1.00 34.65 ? 122 THR A OG1 1 ATOM 950 C CG2 . THR A 1 122 ? 53.007 114.248 34.118 1.00 31.42 ? 122 THR A CG2 1 ATOM 951 N N . SER A 1 123 ? 54.546 110.626 34.556 1.00 32.79 ? 123 SER A N 1 ATOM 952 C CA . SER A 1 123 ? 53.907 109.317 34.340 1.00 34.22 ? 123 SER A CA 1 ATOM 953 C C . SER A 1 123 ? 52.354 109.311 34.458 1.00 36.09 ? 123 SER A C 1 ATOM 954 O O . SER A 1 123 ? 51.680 108.299 34.156 1.00 35.47 ? 123 SER A O 1 ATOM 955 C CB . SER A 1 123 ? 54.536 108.261 35.237 1.00 33.69 ? 123 SER A CB 1 ATOM 956 O OG . SER A 1 123 ? 54.326 108.582 36.590 1.00 35.25 ? 123 SER A OG 1 ATOM 957 N N . SER A 1 124 ? 51.785 110.454 34.839 1.00 36.81 ? 124 SER A N 1 ATOM 958 C CA . SER A 1 124 ? 50.373 110.531 35.180 1.00 37.86 ? 124 SER A CA 1 ATOM 959 C C . SER A 1 124 ? 49.487 110.999 34.032 1.00 37.84 ? 124 SER A C 1 ATOM 960 O O . SER A 1 124 ? 48.288 111.047 34.168 1.00 37.95 ? 124 SER A O 1 ATOM 961 C CB . SER A 1 124 ? 50.158 111.394 36.458 1.00 38.99 ? 124 SER A CB 1 ATOM 962 O OG . SER A 1 124 ? 50.696 112.710 36.348 1.00 39.64 ? 124 SER A OG 1 ATOM 963 N N . LEU A 1 125 ? 50.070 111.325 32.890 1.00 37.57 ? 125 LEU A N 1 ATOM 964 C CA . LEU A 1 125 ? 49.271 111.653 31.728 1.00 36.77 ? 125 LEU A CA 1 ATOM 965 C C . LEU A 1 125 ? 48.270 110.554 31.391 1.00 37.74 ? 125 LEU A C 1 ATOM 966 O O . LEU A 1 125 ? 48.522 109.336 31.542 1.00 37.58 ? 125 LEU A O 1 ATOM 967 C CB . LEU A 1 125 ? 50.134 112.068 30.506 1.00 36.51 ? 125 LEU A CB 1 ATOM 968 C CG . LEU A 1 125 ? 51.258 113.135 30.625 1.00 34.94 ? 125 LEU A CG 1 ATOM 969 C CD1 . LEU A 1 125 ? 51.868 113.473 29.225 1.00 31.55 ? 125 LEU A CD1 1 ATOM 970 C CD2 . LEU A 1 125 ? 50.711 114.407 31.295 1.00 37.69 ? 125 LEU A CD2 1 ATOM 971 N N . HIS A 1 126 ? 47.107 111.018 30.953 1.00 37.80 ? 126 HIS A N 1 ATOM 972 C CA . HIS A 1 126 ? 46.005 110.184 30.499 1.00 38.20 ? 126 HIS A CA 1 ATOM 973 C C . HIS A 1 126 ? 46.466 109.181 29.390 1.00 37.62 ? 126 HIS A C 1 ATOM 974 O O . HIS A 1 126 ? 46.003 108.035 29.341 1.00 36.95 ? 126 HIS A O 1 ATOM 975 C CB . HIS A 1 126 ? 44.897 111.155 29.985 1.00 38.33 ? 126 HIS A CB 1 ATOM 976 C CG . HIS A 1 126 ? 43.727 110.485 29.354 1.00 42.88 ? 126 HIS A CG 1 ATOM 977 N ND1 . HIS A 1 126 ? 42.914 109.601 30.040 1.00 48.52 ? 126 HIS A ND1 1 ATOM 978 C CD2 . HIS A 1 126 ? 43.228 110.562 28.096 1.00 45.65 ? 126 HIS A CD2 1 ATOM 979 C CE1 . HIS A 1 126 ? 41.972 109.157 29.221 1.00 50.28 ? 126 HIS A CE1 1 ATOM 980 N NE2 . HIS A 1 126 ? 42.135 109.730 28.039 1.00 47.77 ? 126 HIS A NE2 1 ATOM 981 N N . VAL A 1 127 ? 47.357 109.634 28.505 1.00 35.98 ? 127 VAL A N 1 ATOM 982 C CA . VAL A 1 127 ? 47.830 108.808 27.386 1.00 35.16 ? 127 VAL A CA 1 ATOM 983 C C . VAL A 1 127 ? 48.817 107.730 27.820 1.00 34.92 ? 127 VAL A C 1 ATOM 984 O O . VAL A 1 127 ? 49.142 106.845 27.034 1.00 36.05 ? 127 VAL A O 1 ATOM 985 C CB . VAL A 1 127 ? 48.402 109.666 26.178 1.00 34.74 ? 127 VAL A CB 1 ATOM 986 C CG1 . VAL A 1 127 ? 47.279 110.421 25.545 1.00 34.88 ? 127 VAL A CG1 1 ATOM 987 C CG2 . VAL A 1 127 ? 49.586 110.617 26.601 1.00 32.68 ? 127 VAL A CG2 1 ATOM 988 N N . TYR A 1 128 ? 49.296 107.810 29.057 1.00 33.56 ? 128 TYR A N 1 ATOM 989 C CA . TYR A 1 128 ? 50.153 106.763 29.640 1.00 33.30 ? 128 TYR A CA 1 ATOM 990 C C . TYR A 1 128 ? 49.440 105.835 30.669 1.00 33.53 ? 128 TYR A C 1 ATOM 991 O O . TYR A 1 128 ? 50.091 105.183 31.499 1.00 33.79 ? 128 TYR A O 1 ATOM 992 C CB . TYR A 1 128 ? 51.362 107.397 30.337 1.00 31.81 ? 128 TYR A CB 1 ATOM 993 C CG . TYR A 1 128 ? 52.140 108.429 29.544 1.00 30.23 ? 128 TYR A CG 1 ATOM 994 C CD1 . TYR A 1 128 ? 52.261 108.351 28.147 1.00 28.09 ? 128 TYR A CD1 1 ATOM 995 C CD2 . TYR A 1 128 ? 52.829 109.456 30.212 1.00 30.86 ? 128 TYR A CD2 1 ATOM 996 C CE1 . TYR A 1 128 ? 53.001 109.336 27.419 1.00 28.90 ? 128 TYR A CE1 1 ATOM 997 C CE2 . TYR A 1 128 ? 53.585 110.384 29.523 1.00 29.96 ? 128 TYR A CE2 1 ATOM 998 C CZ . TYR A 1 128 ? 53.656 110.323 28.110 1.00 28.76 ? 128 TYR A CZ 1 ATOM 999 O OH . TYR A 1 128 ? 54.385 111.245 27.422 1.00 30.93 ? 128 TYR A OH 1 ATOM 1000 N N . ASP A 1 129 ? 48.122 105.812 30.640 1.00 34.12 ? 129 ASP A N 1 ATOM 1001 C CA . ASP A 1 129 ? 47.330 105.083 31.654 1.00 35.30 ? 129 ASP A CA 1 ATOM 1002 C C . ASP A 1 129 ? 47.414 103.589 31.350 1.00 35.57 ? 129 ASP A C 1 ATOM 1003 O O . ASP A 1 129 ? 46.907 103.146 30.315 1.00 35.59 ? 129 ASP A O 1 ATOM 1004 C CB . ASP A 1 129 ? 45.871 105.504 31.543 1.00 36.19 ? 129 ASP A CB 1 ATOM 1005 C CG . ASP A 1 129 ? 45.021 105.076 32.747 1.00 39.16 ? 129 ASP A CG 1 ATOM 1006 O OD1 . ASP A 1 129 ? 45.384 104.108 33.476 1.00 37.70 ? 129 ASP A OD1 1 ATOM 1007 O OD2 . ASP A 1 129 ? 43.953 105.680 32.993 1.00 43.56 ? 129 ASP A OD2 1 ATOM 1008 N N . GLY A 1 130 ? 48.110 102.852 32.213 1.00 35.77 ? 130 GLY A N 1 ATOM 1009 C CA . GLY A 1 130 ? 48.393 101.440 32.024 1.00 36.39 ? 130 GLY A CA 1 ATOM 1010 C C . GLY A 1 130 ? 47.272 100.436 32.277 1.00 38.64 ? 130 GLY A C 1 ATOM 1011 O O . GLY A 1 130 ? 47.473 99.251 32.042 1.00 38.35 ? 130 GLY A O 1 ATOM 1012 N N . LYS A 1 131 ? 46.088 100.893 32.709 1.00 39.07 ? 131 LYS A N 1 ATOM 1013 C CA . LYS A 1 131 ? 44.955 99.995 33.009 1.00 39.99 ? 131 LYS A CA 1 ATOM 1014 C C . LYS A 1 131 ? 44.396 99.188 31.811 1.00 40.39 ? 131 LYS A C 1 ATOM 1015 O O . LYS A 1 131 ? 44.003 98.009 31.955 1.00 41.38 ? 131 LYS A O 1 ATOM 1016 C CB . LYS A 1 131 ? 43.833 100.771 33.752 1.00 40.13 ? 131 LYS A CB 1 ATOM 1017 C CG . LYS A 1 131 ? 43.000 101.612 32.859 1.00 39.63 ? 131 LYS A CG 1 ATOM 1018 C CD . LYS A 1 131 ? 41.976 102.467 33.629 1.00 42.60 ? 131 LYS A CD 1 ATOM 1019 C CE . LYS A 1 131 ? 41.189 103.365 32.664 1.00 44.12 ? 131 LYS A CE 1 ATOM 1020 N NZ . LYS A 1 131 ? 40.065 104.093 33.319 1.00 47.01 ? 131 LYS A NZ 1 ATOM 1021 N N . PHE A 1 132 ? 44.357 99.792 30.629 1.00 40.04 ? 132 PHE A N 1 ATOM 1022 C CA . PHE A 1 132 ? 43.890 99.069 29.454 1.00 39.55 ? 132 PHE A CA 1 ATOM 1023 C C . PHE A 1 132 ? 44.817 97.880 29.119 1.00 39.52 ? 132 PHE A C 1 ATOM 1024 O O . PHE A 1 132 ? 44.352 96.767 28.891 1.00 39.45 ? 132 PHE A O 1 ATOM 1025 C CB . PHE A 1 132 ? 43.757 100.031 28.271 1.00 40.44 ? 132 PHE A CB 1 ATOM 1026 C CG . PHE A 1 132 ? 42.860 101.233 28.555 1.00 42.92 ? 132 PHE A CG 1 ATOM 1027 C CD1 . PHE A 1 132 ? 41.473 101.067 28.746 1.00 42.17 ? 132 PHE A CD1 1 ATOM 1028 C CD2 . PHE A 1 132 ? 43.397 102.513 28.644 1.00 44.57 ? 132 PHE A CD2 1 ATOM 1029 C CE1 . PHE A 1 132 ? 40.638 102.164 29.009 1.00 43.43 ? 132 PHE A CE1 1 ATOM 1030 C CE2 . PHE A 1 132 ? 42.573 103.631 28.922 1.00 46.92 ? 132 PHE A CE2 1 ATOM 1031 C CZ . PHE A 1 132 ? 41.179 103.447 29.093 1.00 46.05 ? 132 PHE A CZ 1 ATOM 1032 N N . LEU A 1 133 ? 46.132 98.112 29.113 1.00 38.77 ? 133 LEU A N 1 ATOM 1033 C CA . LEU A 1 133 ? 47.096 97.050 28.869 1.00 38.54 ? 133 LEU A CA 1 ATOM 1034 C C . LEU A 1 133 ? 46.964 95.892 29.890 1.00 38.98 ? 133 LEU A C 1 ATOM 1035 O O . LEU A 1 133 ? 46.973 94.686 29.508 1.00 37.95 ? 133 LEU A O 1 ATOM 1036 C CB . LEU A 1 133 ? 48.524 97.603 28.842 1.00 38.25 ? 133 LEU A CB 1 ATOM 1037 C CG . LEU A 1 133 ? 48.924 98.403 27.580 1.00 39.67 ? 133 LEU A CG 1 ATOM 1038 C CD1 . LEU A 1 133 ? 50.169 99.305 27.833 1.00 37.91 ? 133 LEU A CD1 1 ATOM 1039 C CD2 . LEU A 1 133 ? 49.138 97.484 26.385 1.00 38.63 ? 133 LEU A CD2 1 ATOM 1040 N N . ALA A 1 134 ? 46.870 96.257 31.171 1.00 38.10 ? 134 ALA A N 1 ATOM 1041 C CA . ALA A 1 134 ? 46.696 95.285 32.238 1.00 39.71 ? 134 ALA A CA 1 ATOM 1042 C C . ALA A 1 134 ? 45.383 94.451 32.024 1.00 40.50 ? 134 ALA A C 1 ATOM 1043 O O . ALA A 1 134 ? 45.397 93.205 31.989 1.00 40.92 ? 134 ALA A O 1 ATOM 1044 C CB . ALA A 1 134 ? 46.731 96.023 33.639 1.00 39.51 ? 134 ALA A CB 1 ATOM 1045 N N . ARG A 1 135 ? 44.276 95.141 31.778 1.00 40.49 ? 135 ARG A N 1 ATOM 1046 C CA . ARG A 1 135 ? 43.025 94.474 31.482 1.00 42.06 ? 135 ARG A CA 1 ATOM 1047 C C . ARG A 1 135 ? 43.125 93.500 30.263 1.00 43.29 ? 135 ARG A C 1 ATOM 1048 O O . ARG A 1 135 ? 42.811 92.300 30.378 1.00 44.55 ? 135 ARG A O 1 ATOM 1049 C CB . ARG A 1 135 ? 41.945 95.531 31.235 1.00 42.40 ? 135 ARG A CB 1 ATOM 1050 C CG . ARG A 1 135 ? 40.551 95.022 30.901 1.00 43.60 ? 135 ARG A CG 1 ATOM 1051 C CD . ARG A 1 135 ? 39.870 94.236 32.039 1.00 50.57 ? 135 ARG A CD 1 ATOM 1052 N NE . ARG A 1 135 ? 38.589 93.725 31.563 1.00 56.03 ? 135 ARG A NE 1 ATOM 1053 C CZ . ARG A 1 135 ? 38.399 92.534 30.989 1.00 59.81 ? 135 ARG A CZ 1 ATOM 1054 N NH1 . ARG A 1 135 ? 39.407 91.672 30.827 1.00 60.42 ? 135 ARG A NH1 1 ATOM 1055 N NH2 . ARG A 1 135 ? 37.178 92.195 30.582 1.00 61.56 ? 135 ARG A NH2 1 ATOM 1056 N N . VAL A 1 136 ? 43.524 94.037 29.113 1.00 42.30 ? 136 VAL A N 1 ATOM 1057 C CA . VAL A 1 136 ? 43.433 93.339 27.850 1.00 41.92 ? 136 VAL A CA 1 ATOM 1058 C C . VAL A 1 136 ? 44.533 92.289 27.640 1.00 41.77 ? 136 VAL A C 1 ATOM 1059 O O . VAL A 1 136 ? 44.253 91.246 27.104 1.00 41.54 ? 136 VAL A O 1 ATOM 1060 C CB . VAL A 1 136 ? 43.398 94.358 26.681 1.00 42.26 ? 136 VAL A CB 1 ATOM 1061 C CG1 . VAL A 1 136 ? 43.477 93.665 25.322 1.00 40.92 ? 136 VAL A CG1 1 ATOM 1062 C CG2 . VAL A 1 136 ? 42.125 95.221 26.777 1.00 41.48 ? 136 VAL A CG2 1 ATOM 1063 N N . GLU A 1 137 ? 45.771 92.556 28.074 1.00 40.81 ? 137 GLU A N 1 ATOM 1064 C CA . GLU A 1 137 ? 46.882 91.623 27.848 1.00 40.35 ? 137 GLU A CA 1 ATOM 1065 C C . GLU A 1 137 ? 47.390 90.860 29.107 1.00 40.19 ? 137 GLU A C 1 ATOM 1066 O O . GLU A 1 137 ? 48.306 90.005 29.024 1.00 39.14 ? 137 GLU A O 1 ATOM 1067 C CB . GLU A 1 137 ? 48.018 92.357 27.065 1.00 39.83 ? 137 GLU A CB 1 ATOM 1068 C CG . GLU A 1 137 ? 47.558 92.788 25.661 1.00 38.25 ? 137 GLU A CG 1 ATOM 1069 C CD . GLU A 1 137 ? 47.309 91.616 24.687 1.00 41.03 ? 137 GLU A CD 1 ATOM 1070 O OE1 . GLU A 1 137 ? 47.906 90.540 24.862 1.00 43.55 ? 137 GLU A OE1 1 ATOM 1071 O OE2 . GLU A 1 137 ? 46.494 91.744 23.728 1.00 41.88 ? 137 GLU A OE2 1 ATOM 1072 N N A ARG A 1 138 ? 46.793 91.142 30.265 0.50 39.95 ? 138 ARG A N 1 ATOM 1073 N N B ARG A 1 138 ? 46.796 91.186 30.257 0.50 39.90 ? 138 ARG A N 1 ATOM 1074 C CA A ARG A 1 138 ? 47.226 90.511 31.517 0.50 39.78 ? 138 ARG A CA 1 ATOM 1075 C CA B ARG A 1 138 ? 47.183 90.594 31.538 0.50 39.68 ? 138 ARG A CA 1 ATOM 1076 C C A ARG A 1 138 ? 48.741 90.676 31.704 0.50 39.62 ? 138 ARG A C 1 ATOM 1077 C C B ARG A 1 138 ? 48.685 90.735 31.803 0.50 39.60 ? 138 ARG A C 1 ATOM 1078 O O A ARG A 1 138 ? 49.446 89.758 32.139 0.50 39.72 ? 138 ARG A O 1 ATOM 1079 O O B ARG A 1 138 ? 49.321 89.858 32.404 0.50 39.68 ? 138 ARG A O 1 ATOM 1080 C CB A ARG A 1 138 ? 46.810 89.017 31.597 0.50 40.13 ? 138 ARG A CB 1 ATOM 1081 C CB B ARG A 1 138 ? 46.727 89.124 31.646 0.50 40.06 ? 138 ARG A CB 1 ATOM 1082 C CG A ARG A 1 138 ? 45.289 88.742 31.643 0.50 41.88 ? 138 ARG A CG 1 ATOM 1083 C CG B ARG A 1 138 ? 45.461 88.892 32.492 0.50 41.61 ? 138 ARG A CG 1 ATOM 1084 C CD A ARG A 1 138 ? 44.879 87.296 32.144 0.50 43.88 ? 138 ARG A CD 1 ATOM 1085 C CD B ARG A 1 138 ? 44.143 88.799 31.718 0.50 42.17 ? 138 ARG A CD 1 ATOM 1086 N NE A ARG A 1 138 ? 45.147 87.057 33.577 0.50 43.75 ? 138 ARG A NE 1 ATOM 1087 N NE B ARG A 1 138 ? 43.366 90.021 31.868 0.50 44.79 ? 138 ARG A NE 1 ATOM 1088 C CZ A ARG A 1 138 ? 44.469 87.617 34.592 0.50 42.86 ? 138 ARG A CZ 1 ATOM 1089 C CZ B ARG A 1 138 ? 42.477 90.249 32.837 0.50 41.91 ? 138 ARG A CZ 1 ATOM 1090 N NH1 A ARG A 1 138 ? 44.803 87.332 35.839 0.50 40.40 ? 138 ARG A NH1 1 ATOM 1091 N NH1 B ARG A 1 138 ? 42.236 89.319 33.768 0.50 41.99 ? 138 ARG A NH1 1 ATOM 1092 N NH2 A ARG A 1 138 ? 43.466 88.475 34.370 0.50 43.66 ? 138 ARG A NH2 1 ATOM 1093 N NH2 B ARG A 1 138 ? 41.852 91.420 32.873 0.50 36.73 ? 138 ARG A NH2 1 ATOM 1094 N N . VAL A 1 139 ? 49.247 91.851 31.352 1.00 38.79 ? 139 VAL A N 1 ATOM 1095 C CA . VAL A 1 139 ? 50.589 92.226 31.739 1.00 38.44 ? 139 VAL A CA 1 ATOM 1096 C C . VAL A 1 139 ? 50.442 93.139 32.931 1.00 38.84 ? 139 VAL A C 1 ATOM 1097 O O . VAL A 1 139 ? 49.374 93.678 33.153 1.00 39.62 ? 139 VAL A O 1 ATOM 1098 C CB . VAL A 1 139 ? 51.378 92.920 30.587 1.00 37.66 ? 139 VAL A CB 1 ATOM 1099 C CG1 . VAL A 1 139 ? 51.701 91.877 29.519 1.00 35.72 ? 139 VAL A CG1 1 ATOM 1100 C CG2 . VAL A 1 139 ? 50.589 94.047 29.982 1.00 34.18 ? 139 VAL A CG2 1 ATOM 1101 N N . ILE A 1 140 ? 51.518 93.275 33.698 1.00 38.61 ? 140 ILE A N 1 ATOM 1102 C CA . ILE A 1 140 ? 51.682 94.349 34.650 1.00 36.99 ? 140 ILE A CA 1 ATOM 1103 C C . ILE A 1 140 ? 52.352 95.534 33.934 1.00 36.97 ? 140 ILE A C 1 ATOM 1104 O O . ILE A 1 140 ? 53.322 95.350 33.155 1.00 36.42 ? 140 ILE A O 1 ATOM 1105 C CB . ILE A 1 140 ? 52.531 93.827 35.814 1.00 37.30 ? 140 ILE A CB 1 ATOM 1106 C CG1 . ILE A 1 140 ? 51.700 92.758 36.576 1.00 37.78 ? 140 ILE A CG1 1 ATOM 1107 C CG2 . ILE A 1 140 ? 52.974 94.951 36.712 1.00 34.68 ? 140 ILE A CG2 1 ATOM 1108 C CD1 . ILE A 1 140 ? 52.373 92.205 37.883 1.00 37.46 ? 140 ILE A CD1 1 ATOM 1109 N N . VAL A 1 141 ? 51.795 96.730 34.151 1.00 36.11 ? 141 VAL A N 1 ATOM 1110 C CA . VAL A 1 141 ? 52.399 97.978 33.674 1.00 35.73 ? 141 VAL A CA 1 ATOM 1111 C C . VAL A 1 141 ? 52.974 98.760 34.872 1.00 35.82 ? 141 VAL A C 1 ATOM 1112 O O . VAL A 1 141 ? 52.298 98.986 35.884 1.00 36.48 ? 141 VAL A O 1 ATOM 1113 C CB . VAL A 1 141 ? 51.374 98.807 32.898 1.00 34.71 ? 141 VAL A CB 1 ATOM 1114 C CG1 . VAL A 1 141 ? 51.986 100.072 32.280 1.00 35.43 ? 141 VAL A CG1 1 ATOM 1115 C CG2 . VAL A 1 141 ? 50.680 97.927 31.852 1.00 35.84 ? 141 VAL A CG2 1 ATOM 1116 N N . VAL A 1 142 ? 54.239 99.128 34.773 1.00 34.99 ? 142 VAL A N 1 ATOM 1117 C CA . VAL A 1 142 ? 54.849 100.032 35.740 1.00 35.04 ? 142 VAL A CA 1 ATOM 1118 C C . VAL A 1 142 ? 55.256 101.326 34.997 1.00 35.69 ? 142 VAL A C 1 ATOM 1119 O O . VAL A 1 142 ? 55.644 101.271 33.788 1.00 34.87 ? 142 VAL A O 1 ATOM 1120 C CB . VAL A 1 142 ? 56.061 99.377 36.418 1.00 35.01 ? 142 VAL A CB 1 ATOM 1121 C CG1 . VAL A 1 142 ? 56.773 100.332 37.294 1.00 34.26 ? 142 VAL A CG1 1 ATOM 1122 C CG2 . VAL A 1 142 ? 55.655 98.074 37.173 1.00 34.62 ? 142 VAL A CG2 1 ATOM 1123 N N . SER A 1 143 ? 55.086 102.472 35.671 1.00 35.06 ? 143 SER A N 1 ATOM 1124 C CA . SER A 1 143 ? 55.619 103.756 35.190 1.00 35.07 ? 143 SER A CA 1 ATOM 1125 C C . SER A 1 143 ? 56.213 104.576 36.337 1.00 34.93 ? 143 SER A C 1 ATOM 1126 O O . SER A 1 143 ? 55.803 104.414 37.472 1.00 35.06 ? 143 SER A O 1 ATOM 1127 C CB . SER A 1 143 ? 54.564 104.537 34.411 1.00 34.88 ? 143 SER A CB 1 ATOM 1128 O OG . SER A 1 143 ? 53.564 105.075 35.256 1.00 37.63 ? 143 SER A OG 1 ATOM 1129 N N . MET A 1 144 ? 57.227 105.404 36.057 1.00 34.52 ? 144 MET A N 1 ATOM 1130 C CA . MET A 1 144 ? 57.856 106.218 37.101 1.00 33.31 ? 144 MET A CA 1 ATOM 1131 C C . MET A 1 144 ? 58.020 107.690 36.719 1.00 33.77 ? 144 MET A C 1 ATOM 1132 O O . MET A 1 144 ? 58.169 108.034 35.512 1.00 33.46 ? 144 MET A O 1 ATOM 1133 C CB . MET A 1 144 ? 59.219 105.623 37.544 1.00 33.01 ? 144 MET A CB 1 ATOM 1134 C CG . MET A 1 144 ? 60.472 106.042 36.758 1.00 31.31 ? 144 MET A CG 1 ATOM 1135 S SD . MET A 1 144 ? 60.452 105.586 34.976 1.00 34.87 ? 144 MET A SD 1 ATOM 1136 C CE . MET A 1 144 ? 60.949 103.838 35.087 1.00 26.53 ? 144 MET A CE 1 ATOM 1137 N N . ASN A 1 145 ? 58.039 108.550 37.740 1.00 33.39 ? 145 ASN A N 1 ATOM 1138 C CA . ASN A 1 145 ? 58.524 109.909 37.543 1.00 35.27 ? 145 ASN A CA 1 ATOM 1139 C C . ASN A 1 145 ? 60.009 109.961 37.810 1.00 35.62 ? 145 ASN A C 1 ATOM 1140 O O . ASN A 1 145 ? 60.534 109.338 38.766 1.00 35.57 ? 145 ASN A O 1 ATOM 1141 C CB . ASN A 1 145 ? 57.814 110.947 38.434 1.00 35.17 ? 145 ASN A CB 1 ATOM 1142 C CG . ASN A 1 145 ? 56.351 111.057 38.155 1.00 36.69 ? 145 ASN A CG 1 ATOM 1143 O OD1 . ASN A 1 145 ? 55.877 110.656 37.096 1.00 37.67 ? 145 ASN A OD1 1 ATOM 1144 N ND2 . ASN A 1 145 ? 55.601 111.615 39.109 1.00 38.76 ? 145 ASN A ND2 1 ATOM 1145 N N . TYR A 1 146 ? 60.703 110.697 36.946 1.00 35.55 ? 146 TYR A N 1 ATOM 1146 C CA . TYR A 1 146 ? 62.133 110.846 37.112 1.00 34.21 ? 146 TYR A CA 1 ATOM 1147 C C . TYR A 1 146 ? 62.418 112.344 36.934 1.00 33.97 ? 146 TYR A C 1 ATOM 1148 O O . TYR A 1 146 ? 61.684 113.003 36.226 1.00 33.20 ? 146 TYR A O 1 ATOM 1149 C CB . TYR A 1 146 ? 62.880 109.974 36.086 1.00 33.34 ? 146 TYR A CB 1 ATOM 1150 C CG . TYR A 1 146 ? 62.632 110.305 34.615 1.00 30.48 ? 146 TYR A CG 1 ATOM 1151 C CD1 . TYR A 1 146 ? 63.413 111.253 33.958 1.00 30.25 ? 146 TYR A CD1 1 ATOM 1152 C CD2 . TYR A 1 146 ? 61.605 109.679 33.890 1.00 29.40 ? 146 TYR A CD2 1 ATOM 1153 C CE1 . TYR A 1 146 ? 63.192 111.582 32.620 1.00 28.97 ? 146 TYR A CE1 1 ATOM 1154 C CE2 . TYR A 1 146 ? 61.412 109.960 32.525 1.00 30.93 ? 146 TYR A CE2 1 ATOM 1155 C CZ . TYR A 1 146 ? 62.215 110.920 31.907 1.00 30.79 ? 146 TYR A CZ 1 ATOM 1156 O OH . TYR A 1 146 ? 62.043 111.265 30.582 1.00 31.63 ? 146 TYR A OH 1 ATOM 1157 N N . ARG A 1 147 ? 63.452 112.865 37.597 1.00 34.10 ? 147 ARG A N 1 ATOM 1158 C CA . ARG A 1 147 ? 63.787 114.274 37.510 1.00 33.50 ? 147 ARG A CA 1 ATOM 1159 C C . ARG A 1 147 ? 64.210 114.668 36.085 1.00 34.47 ? 147 ARG A C 1 ATOM 1160 O O . ARG A 1 147 ? 64.878 113.880 35.358 1.00 34.69 ? 147 ARG A O 1 ATOM 1161 C CB . ARG A 1 147 ? 64.870 114.630 38.521 1.00 33.57 ? 147 ARG A CB 1 ATOM 1162 C CG . ARG A 1 147 ? 64.433 114.460 39.999 1.00 33.78 ? 147 ARG A CG 1 ATOM 1163 C CD . ARG A 1 147 ? 65.596 114.568 40.975 1.00 34.76 ? 147 ARG A CD 1 ATOM 1164 N NE . ARG A 1 147 ? 66.305 113.303 41.112 1.00 32.98 ? 147 ARG A NE 1 ATOM 1165 C CZ . ARG A 1 147 ? 67.469 113.146 41.726 1.00 35.38 ? 147 ARG A CZ 1 ATOM 1166 N NH1 . ARG A 1 147 ? 68.116 114.215 42.242 1.00 35.82 ? 147 ARG A NH1 1 ATOM 1167 N NH2 . ARG A 1 147 ? 67.995 111.922 41.815 1.00 30.13 ? 147 ARG A NH2 1 ATOM 1168 N N . VAL A 1 148 ? 63.823 115.882 35.705 1.00 32.84 ? 148 VAL A N 1 ATOM 1169 C CA . VAL A 1 148 ? 64.051 116.422 34.379 1.00 33.72 ? 148 VAL A CA 1 ATOM 1170 C C . VAL A 1 148 ? 64.652 117.839 34.569 1.00 35.51 ? 148 VAL A C 1 ATOM 1171 O O . VAL A 1 148 ? 64.689 118.386 35.702 1.00 35.68 ? 148 VAL A O 1 ATOM 1172 C CB . VAL A 1 148 ? 62.705 116.425 33.571 1.00 34.26 ? 148 VAL A CB 1 ATOM 1173 C CG1 . VAL A 1 148 ? 62.275 114.995 33.212 1.00 31.23 ? 148 VAL A CG1 1 ATOM 1174 C CG2 . VAL A 1 148 ? 61.530 117.161 34.355 1.00 29.94 ? 148 VAL A CG2 1 ATOM 1175 N N . GLY A 1 149 ? 65.171 118.393 33.494 1.00 35.74 ? 149 GLY A N 1 ATOM 1176 C CA . GLY A 1 149 ? 65.824 119.697 33.517 1.00 36.58 ? 149 GLY A CA 1 ATOM 1177 C C . GLY A 1 149 ? 67.110 119.637 34.289 1.00 37.85 ? 149 GLY A C 1 ATOM 1178 O O . GLY A 1 149 ? 67.736 118.553 34.391 1.00 37.75 ? 149 GLY A O 1 ATOM 1179 N N . ALA A 1 150 ? 67.482 120.776 34.888 1.00 37.11 ? 150 ALA A N 1 ATOM 1180 C CA . ALA A 1 150 ? 68.735 120.880 35.609 1.00 37.50 ? 150 ALA A CA 1 ATOM 1181 C C . ALA A 1 150 ? 68.685 120.058 36.844 1.00 37.65 ? 150 ALA A C 1 ATOM 1182 O O . ALA A 1 150 ? 69.707 119.580 37.311 1.00 38.30 ? 150 ALA A O 1 ATOM 1183 C CB . ALA A 1 150 ? 69.060 122.384 35.971 1.00 38.45 ? 150 ALA A CB 1 ATOM 1184 N N . LEU A 1 151 ? 67.499 119.911 37.421 1.00 38.10 ? 151 LEU A N 1 ATOM 1185 C CA . LEU A 1 151 ? 67.367 119.127 38.656 1.00 38.59 ? 151 LEU A CA 1 ATOM 1186 C C . LEU A 1 151 ? 67.626 117.621 38.423 1.00 39.21 ? 151 LEU A C 1 ATOM 1187 O O . LEU A 1 151 ? 67.954 116.877 39.368 1.00 38.14 ? 151 LEU A O 1 ATOM 1188 C CB . LEU A 1 151 ? 65.961 119.321 39.254 1.00 39.57 ? 151 LEU A CB 1 ATOM 1189 C CG . LEU A 1 151 ? 65.650 120.733 39.804 1.00 40.85 ? 151 LEU A CG 1 ATOM 1190 C CD1 . LEU A 1 151 ? 64.144 120.972 40.006 1.00 41.26 ? 151 LEU A CD1 1 ATOM 1191 C CD2 . LEU A 1 151 ? 66.443 120.997 41.112 1.00 38.63 ? 151 LEU A CD2 1 ATOM 1192 N N . GLY A 1 152 ? 67.440 117.193 37.166 1.00 38.78 ? 152 GLY A N 1 ATOM 1193 C CA . GLY A 1 152 ? 67.677 115.805 36.744 1.00 39.39 ? 152 GLY A CA 1 ATOM 1194 C C . GLY A 1 152 ? 69.021 115.578 36.063 1.00 39.10 ? 152 GLY A C 1 ATOM 1195 O O . GLY A 1 152 ? 69.574 114.470 36.122 1.00 39.52 ? 152 GLY A O 1 ATOM 1196 N N . PHE A 1 153 ? 69.571 116.620 35.459 1.00 39.32 ? 153 PHE A N 1 ATOM 1197 C CA . PHE A 1 153 ? 70.692 116.446 34.529 1.00 39.64 ? 153 PHE A CA 1 ATOM 1198 C C . PHE A 1 153 ? 71.827 117.473 34.577 1.00 41.11 ? 153 PHE A C 1 ATOM 1199 O O . PHE A 1 153 ? 72.793 117.394 33.777 1.00 41.74 ? 153 PHE A O 1 ATOM 1200 C CB . PHE A 1 153 ? 70.126 116.315 33.113 1.00 38.72 ? 153 PHE A CB 1 ATOM 1201 C CG . PHE A 1 153 ? 69.279 115.058 32.916 1.00 36.05 ? 153 PHE A CG 1 ATOM 1202 C CD1 . PHE A 1 153 ? 69.893 113.812 32.697 1.00 34.74 ? 153 PHE A CD1 1 ATOM 1203 C CD2 . PHE A 1 153 ? 67.869 115.121 32.975 1.00 32.66 ? 153 PHE A CD2 1 ATOM 1204 C CE1 . PHE A 1 153 ? 69.106 112.623 32.483 1.00 35.62 ? 153 PHE A CE1 1 ATOM 1205 C CE2 . PHE A 1 153 ? 67.067 113.939 32.800 1.00 33.26 ? 153 PHE A CE2 1 ATOM 1206 C CZ . PHE A 1 153 ? 67.686 112.697 32.555 1.00 31.96 ? 153 PHE A CZ 1 ATOM 1207 N N . LEU A 1 154 ? 71.742 118.440 35.497 1.00 42.44 ? 154 LEU A N 1 ATOM 1208 C CA . LEU A 1 154 ? 72.907 119.305 35.758 1.00 43.65 ? 154 LEU A CA 1 ATOM 1209 C C . LEU A 1 154 ? 74.157 118.431 35.982 1.00 44.60 ? 154 LEU A C 1 ATOM 1210 O O . LEU A 1 154 ? 74.133 117.475 36.765 1.00 43.35 ? 154 LEU A O 1 ATOM 1211 C CB . LEU A 1 154 ? 72.689 120.172 36.983 1.00 43.91 ? 154 LEU A CB 1 ATOM 1212 C CG . LEU A 1 154 ? 73.743 121.215 37.404 1.00 44.59 ? 154 LEU A CG 1 ATOM 1213 C CD1 . LEU A 1 154 ? 73.341 122.550 36.907 1.00 45.09 ? 154 LEU A CD1 1 ATOM 1214 C CD2 . LEU A 1 154 ? 73.756 121.266 38.900 1.00 43.49 ? 154 LEU A CD2 1 ATOM 1215 N N . ALA A 1 155 ? 75.235 118.777 35.290 1.00 45.86 ? 155 ALA A N 1 ATOM 1216 C CA . ALA A 1 155 ? 76.457 117.983 35.325 1.00 48.06 ? 155 ALA A CA 1 ATOM 1217 C C . ALA A 1 155 ? 77.700 118.845 35.595 1.00 49.80 ? 155 ALA A C 1 ATOM 1218 O O . ALA A 1 155 ? 77.899 119.902 34.973 1.00 48.33 ? 155 ALA A O 1 ATOM 1219 C CB . ALA A 1 155 ? 76.629 117.186 33.980 1.00 47.48 ? 155 ALA A CB 1 ATOM 1220 N N . LEU A 1 156 ? 78.493 118.376 36.548 1.00 52.69 ? 156 LEU A N 1 ATOM 1221 C CA . LEU A 1 156 ? 79.896 118.757 36.699 1.00 56.46 ? 156 LEU A CA 1 ATOM 1222 C C . LEU A 1 156 ? 80.642 117.430 36.807 1.00 58.56 ? 156 LEU A C 1 ATOM 1223 O O . LEU A 1 156 ? 80.680 116.806 37.887 1.00 58.59 ? 156 LEU A O 1 ATOM 1224 C CB . LEU A 1 156 ? 80.090 119.547 37.981 1.00 56.88 ? 156 LEU A CB 1 ATOM 1225 C CG . LEU A 1 156 ? 80.356 121.040 38.018 1.00 57.93 ? 156 LEU A CG 1 ATOM 1226 C CD1 . LEU A 1 156 ? 80.012 121.772 36.723 1.00 58.45 ? 156 LEU A CD1 1 ATOM 1227 C CD2 . LEU A 1 156 ? 79.630 121.602 39.235 1.00 58.19 ? 156 LEU A CD2 1 ATOM 1228 N N . PRO A 1 157 ? 81.186 116.981 35.676 1.00 60.68 ? 157 PRO A N 1 ATOM 1229 C CA . PRO A 1 157 ? 81.796 115.654 35.554 1.00 62.32 ? 157 PRO A CA 1 ATOM 1230 C C . PRO A 1 157 ? 82.614 115.236 36.777 1.00 63.39 ? 157 PRO A C 1 ATOM 1231 O O . PRO A 1 157 ? 83.508 115.984 37.222 1.00 63.89 ? 157 PRO A O 1 ATOM 1232 C CB . PRO A 1 157 ? 82.708 115.824 34.341 1.00 62.47 ? 157 PRO A CB 1 ATOM 1233 C CG . PRO A 1 157 ? 81.960 116.820 33.474 1.00 62.03 ? 157 PRO A CG 1 ATOM 1234 C CD . PRO A 1 157 ? 81.227 117.723 34.401 1.00 60.76 ? 157 PRO A CD 1 ATOM 1235 N N . GLY A 1 158 ? 82.268 114.077 37.335 1.00 63.73 ? 158 GLY A N 1 ATOM 1236 C CA . GLY A 1 158 ? 83.035 113.486 38.433 1.00 64.32 ? 158 GLY A CA 1 ATOM 1237 C C . GLY A 1 158 ? 82.695 113.954 39.834 1.00 64.69 ? 158 GLY A C 1 ATOM 1238 O O . GLY A 1 158 ? 83.059 113.289 40.807 1.00 65.29 ? 158 GLY A O 1 ATOM 1239 N N . ASN A 1 159 ? 81.984 115.085 39.933 1.00 64.46 ? 159 ASN A N 1 ATOM 1240 C CA . ASN A 1 159 ? 81.632 115.738 41.203 1.00 63.15 ? 159 ASN A CA 1 ATOM 1241 C C . ASN A 1 159 ? 80.309 115.177 41.718 1.00 62.55 ? 159 ASN A C 1 ATOM 1242 O O . ASN A 1 159 ? 79.263 115.506 41.143 1.00 62.57 ? 159 ASN A O 1 ATOM 1243 C CB . ASN A 1 159 ? 81.492 117.235 40.925 1.00 63.33 ? 159 ASN A CB 1 ATOM 1244 C CG . ASN A 1 159 ? 81.394 118.079 42.182 1.00 64.10 ? 159 ASN A CG 1 ATOM 1245 O OD1 . ASN A 1 159 ? 80.898 117.639 43.225 1.00 61.91 ? 159 ASN A OD1 1 ATOM 1246 N ND2 . ASN A 1 159 ? 81.841 119.334 42.069 1.00 66.42 ? 159 ASN A ND2 1 ATOM 1247 N N . PRO A 1 160 ? 80.321 114.368 42.791 1.00 61.67 ? 160 PRO A N 1 ATOM 1248 C CA . PRO A 1 160 ? 79.097 113.663 43.235 1.00 60.63 ? 160 PRO A CA 1 ATOM 1249 C C . PRO A 1 160 ? 78.015 114.593 43.787 1.00 60.06 ? 160 PRO A C 1 ATOM 1250 O O . PRO A 1 160 ? 76.898 114.148 44.097 1.00 60.40 ? 160 PRO A O 1 ATOM 1251 C CB . PRO A 1 160 ? 79.595 112.681 44.312 1.00 60.61 ? 160 PRO A CB 1 ATOM 1252 C CG . PRO A 1 160 ? 80.917 113.228 44.768 1.00 61.09 ? 160 PRO A CG 1 ATOM 1253 C CD . PRO A 1 160 ? 81.480 114.069 43.660 1.00 61.62 ? 160 PRO A CD 1 ATOM 1254 N N . GLU A 1 161 ? 78.332 115.876 43.905 1.00 58.94 ? 161 GLU A N 1 ATOM 1255 C CA . GLU A 1 161 ? 77.311 116.860 44.271 1.00 57.81 ? 161 GLU A CA 1 ATOM 1256 C C . GLU A 1 161 ? 76.375 117.147 43.110 1.00 55.36 ? 161 GLU A C 1 ATOM 1257 O O . GLU A 1 161 ? 75.220 117.486 43.334 1.00 54.97 ? 161 GLU A O 1 ATOM 1258 C CB . GLU A 1 161 ? 77.933 118.168 44.800 1.00 58.03 ? 161 GLU A CB 1 ATOM 1259 C CG . GLU A 1 161 ? 77.819 118.277 46.308 1.00 61.32 ? 161 GLU A CG 1 ATOM 1260 C CD . GLU A 1 161 ? 78.651 117.242 47.031 1.00 65.68 ? 161 GLU A CD 1 ATOM 1261 O OE1 . GLU A 1 161 ? 78.101 116.433 47.836 1.00 66.83 ? 161 GLU A OE1 1 ATOM 1262 O OE2 . GLU A 1 161 ? 79.867 117.233 46.779 1.00 68.73 ? 161 GLU A OE2 1 ATOM 1263 N N . ALA A 1 162 ? 76.908 117.050 41.891 1.00 52.68 ? 162 ALA A N 1 ATOM 1264 C CA . ALA A 1 162 ? 76.130 117.202 40.649 1.00 50.32 ? 162 ALA A CA 1 ATOM 1265 C C . ALA A 1 162 ? 76.775 116.374 39.535 1.00 47.99 ? 162 ALA A C 1 ATOM 1266 O O . ALA A 1 162 ? 77.404 116.939 38.638 1.00 47.39 ? 162 ALA A O 1 ATOM 1267 C CB . ALA A 1 162 ? 76.032 118.681 40.232 1.00 50.14 ? 162 ALA A CB 1 ATOM 1268 N N . PRO A 1 163 ? 76.653 115.044 39.607 1.00 46.07 ? 163 PRO A N 1 ATOM 1269 C CA . PRO A 1 163 ? 77.433 114.181 38.730 1.00 44.84 ? 163 PRO A CA 1 ATOM 1270 C C . PRO A 1 163 ? 76.903 114.149 37.290 1.00 43.69 ? 163 PRO A C 1 ATOM 1271 O O . PRO A 1 163 ? 77.699 113.873 36.370 1.00 43.95 ? 163 PRO A O 1 ATOM 1272 C CB . PRO A 1 163 ? 77.356 112.813 39.404 1.00 44.53 ? 163 PRO A CB 1 ATOM 1273 C CG . PRO A 1 163 ? 76.096 112.824 40.179 1.00 45.23 ? 163 PRO A CG 1 ATOM 1274 C CD . PRO A 1 163 ? 75.781 114.264 40.505 1.00 46.24 ? 163 PRO A CD 1 ATOM 1275 N N . GLY A 1 164 ? 75.619 114.507 37.104 1.00 40.99 ? 164 GLY A N 1 ATOM 1276 C CA . GLY A 1 164 ? 74.922 114.365 35.828 1.00 38.97 ? 164 GLY A CA 1 ATOM 1277 C C . GLY A 1 164 ? 74.121 113.071 35.815 1.00 37.90 ? 164 GLY A C 1 ATOM 1278 O O . GLY A 1 164 ? 74.307 112.211 36.687 1.00 36.07 ? 164 GLY A O 1 ATOM 1279 N N . ASN A 1 165 ? 73.186 112.961 34.863 1.00 36.77 ? 165 ASN A N 1 ATOM 1280 C CA . ASN A 1 165 ? 72.387 111.713 34.673 1.00 35.70 ? 165 ASN A CA 1 ATOM 1281 C C . ASN A 1 165 ? 71.525 111.293 35.847 1.00 35.36 ? 165 ASN A C 1 ATOM 1282 O O . ASN A 1 165 ? 71.086 110.151 35.940 1.00 34.89 ? 165 ASN A O 1 ATOM 1283 C CB . ASN A 1 165 ? 73.314 110.552 34.260 1.00 34.51 ? 165 ASN A CB 1 ATOM 1284 C CG . ASN A 1 165 ? 73.937 110.772 32.914 1.00 35.43 ? 165 ASN A CG 1 ATOM 1285 O OD1 . ASN A 1 165 ? 73.501 111.658 32.139 1.00 33.36 ? 165 ASN A OD1 1 ATOM 1286 N ND2 . ASN A 1 165 ? 74.970 109.977 32.601 1.00 35.01 ? 165 ASN A ND2 1 ATOM 1287 N N . MET A 1 166 ? 71.253 112.217 36.757 1.00 35.36 ? 166 MET A N 1 ATOM 1288 C CA . MET A 1 166 ? 70.520 111.847 37.967 1.00 35.16 ? 166 MET A CA 1 ATOM 1289 C C . MET A 1 166 ? 69.135 111.265 37.627 1.00 34.82 ? 166 MET A C 1 ATOM 1290 O O . MET A 1 166 ? 68.669 110.289 38.273 1.00 35.13 ? 166 MET A O 1 ATOM 1291 C CB . MET A 1 166 ? 70.421 113.089 38.896 1.00 36.34 ? 166 MET A CB 1 ATOM 1292 C CG . MET A 1 166 ? 71.802 113.623 39.360 1.00 34.43 ? 166 MET A CG 1 ATOM 1293 S SD . MET A 1 166 ? 72.559 114.836 38.259 1.00 41.58 ? 166 MET A SD 1 ATOM 1294 C CE . MET A 1 166 ? 71.519 116.301 38.494 1.00 38.36 ? 166 MET A CE 1 ATOM 1295 N N . GLY A 1 167 ? 68.483 111.857 36.620 1.00 34.52 ? 167 GLY A N 1 ATOM 1296 C CA . GLY A 1 167 ? 67.148 111.388 36.161 1.00 34.48 ? 167 GLY A CA 1 ATOM 1297 C C . GLY A 1 167 ? 67.185 109.977 35.558 1.00 34.46 ? 167 GLY A C 1 ATOM 1298 O O . GLY A 1 167 ? 66.272 109.186 35.704 1.00 35.17 ? 167 GLY A O 1 ATOM 1299 N N . LEU A 1 168 ? 68.268 109.663 34.867 1.00 34.91 ? 168 LEU A N 1 ATOM 1300 C CA . LEU A 1 168 ? 68.544 108.293 34.405 1.00 33.45 ? 168 LEU A CA 1 ATOM 1301 C C . LEU A 1 168 ? 68.800 107.329 35.585 1.00 32.99 ? 168 LEU A C 1 ATOM 1302 O O . LEU A 1 168 ? 68.297 106.204 35.572 1.00 31.95 ? 168 LEU A O 1 ATOM 1303 C CB . LEU A 1 168 ? 69.717 108.331 33.434 1.00 33.45 ? 168 LEU A CB 1 ATOM 1304 C CG . LEU A 1 168 ? 69.481 108.947 32.053 1.00 31.88 ? 168 LEU A CG 1 ATOM 1305 C CD1 . LEU A 1 168 ? 70.811 109.035 31.308 1.00 29.85 ? 168 LEU A CD1 1 ATOM 1306 C CD2 . LEU A 1 168 ? 68.471 108.140 31.269 1.00 32.32 ? 168 LEU A CD2 1 ATOM 1307 N N . PHE A 1 169 ? 69.536 107.777 36.617 1.00 32.75 ? 169 PHE A N 1 ATOM 1308 C CA . PHE A 1 169 ? 69.602 107.017 37.872 1.00 34.15 ? 169 PHE A CA 1 ATOM 1309 C C . PHE A 1 169 ? 68.254 106.876 38.615 1.00 34.54 ? 169 PHE A C 1 ATOM 1310 O O . PHE A 1 169 ? 68.003 105.868 39.297 1.00 36.49 ? 169 PHE A O 1 ATOM 1311 C CB . PHE A 1 169 ? 70.727 107.533 38.795 1.00 34.07 ? 169 PHE A CB 1 ATOM 1312 C CG . PHE A 1 169 ? 72.112 107.105 38.356 1.00 34.41 ? 169 PHE A CG 1 ATOM 1313 C CD1 . PHE A 1 169 ? 73.041 108.039 37.935 1.00 35.08 ? 169 PHE A CD1 1 ATOM 1314 C CD2 . PHE A 1 169 ? 72.481 105.770 38.415 1.00 33.56 ? 169 PHE A CD2 1 ATOM 1315 C CE1 . PHE A 1 169 ? 74.324 107.638 37.523 1.00 38.46 ? 169 PHE A CE1 1 ATOM 1316 C CE2 . PHE A 1 169 ? 73.760 105.353 38.018 1.00 36.94 ? 169 PHE A CE2 1 ATOM 1317 C CZ . PHE A 1 169 ? 74.684 106.295 37.581 1.00 38.30 ? 169 PHE A CZ 1 ATOM 1318 N N . ASP A 1 170 ? 67.363 107.857 38.462 1.00 35.16 ? 170 ASP A N 1 ATOM 1319 C CA . ASP A 1 170 ? 66.022 107.716 39.028 1.00 34.30 ? 170 ASP A CA 1 ATOM 1320 C C . ASP A 1 170 ? 65.305 106.533 38.333 1.00 34.32 ? 170 ASP A C 1 ATOM 1321 O O . ASP A 1 170 ? 64.729 105.657 39.001 1.00 35.05 ? 170 ASP A O 1 ATOM 1322 C CB . ASP A 1 170 ? 65.186 109.000 38.836 1.00 33.98 ? 170 ASP A CB 1 ATOM 1323 C CG . ASP A 1 170 ? 65.688 110.193 39.662 1.00 37.72 ? 170 ASP A CG 1 ATOM 1324 O OD1 . ASP A 1 170 ? 66.453 110.019 40.628 1.00 39.43 ? 170 ASP A OD1 1 ATOM 1325 O OD2 . ASP A 1 170 ? 65.367 111.366 39.389 1.00 39.39 ? 170 ASP A OD2 1 ATOM 1326 N N . GLN A 1 171 ? 65.271 106.564 36.991 1.00 32.92 ? 171 GLN A N 1 ATOM 1327 C CA . GLN A 1 171 ? 64.740 105.472 36.196 1.00 31.37 ? 171 GLN A CA 1 ATOM 1328 C C . GLN A 1 171 ? 65.347 104.136 36.641 1.00 31.37 ? 171 GLN A C 1 ATOM 1329 O O . GLN A 1 171 ? 64.620 103.189 36.858 1.00 31.72 ? 171 GLN A O 1 ATOM 1330 C CB . GLN A 1 171 ? 64.983 105.707 34.707 1.00 30.66 ? 171 GLN A CB 1 ATOM 1331 C CG . GLN A 1 171 ? 64.353 106.976 34.146 1.00 30.83 ? 171 GLN A CG 1 ATOM 1332 C CD . GLN A 1 171 ? 64.802 107.231 32.746 1.00 34.77 ? 171 GLN A CD 1 ATOM 1333 O OE1 . GLN A 1 171 ? 65.319 106.296 32.072 1.00 32.78 ? 171 GLN A OE1 1 ATOM 1334 N NE2 . GLN A 1 171 ? 64.624 108.485 32.271 1.00 31.72 ? 171 GLN A NE2 1 ATOM 1335 N N . GLN A 1 172 ? 66.655 104.077 36.844 1.00 33.02 ? 172 GLN A N 1 ATOM 1336 C CA . GLN A 1 172 ? 67.327 102.817 37.185 1.00 34.58 ? 172 GLN A CA 1 ATOM 1337 C C . GLN A 1 172 ? 66.947 102.297 38.574 1.00 36.32 ? 172 GLN A C 1 ATOM 1338 O O . GLN A 1 172 ? 66.727 101.099 38.776 1.00 36.98 ? 172 GLN A O 1 ATOM 1339 C CB . GLN A 1 172 ? 68.844 102.990 37.053 1.00 34.44 ? 172 GLN A CB 1 ATOM 1340 C CG . GLN A 1 172 ? 69.609 101.668 37.073 1.00 35.54 ? 172 GLN A CG 1 ATOM 1341 C CD . GLN A 1 172 ? 71.105 101.896 37.098 1.00 36.73 ? 172 GLN A CD 1 ATOM 1342 O OE1 . GLN A 1 172 ? 71.776 101.829 36.054 1.00 39.89 ? 172 GLN A OE1 1 ATOM 1343 N NE2 . GLN A 1 172 ? 71.628 102.219 38.265 1.00 36.03 ? 172 GLN A NE2 1 ATOM 1344 N N . LEU A 1 173 ? 66.835 103.203 39.542 1.00 37.38 ? 173 LEU A N 1 ATOM 1345 C CA . LEU A 1 173 ? 66.413 102.804 40.888 1.00 36.38 ? 173 LEU A CA 1 ATOM 1346 C C . LEU A 1 173 ? 64.985 102.293 40.830 1.00 36.70 ? 173 LEU A C 1 ATOM 1347 O O . LEU A 1 173 ? 64.639 101.347 41.522 1.00 37.11 ? 173 LEU A O 1 ATOM 1348 C CB . LEU A 1 173 ? 66.561 103.977 41.895 1.00 37.00 ? 173 LEU A CB 1 ATOM 1349 C CG . LEU A 1 173 ? 66.395 103.708 43.419 1.00 39.02 ? 173 LEU A CG 1 ATOM 1350 C CD1 . LEU A 1 173 ? 67.334 102.582 43.926 1.00 40.59 ? 173 LEU A CD1 1 ATOM 1351 C CD2 . LEU A 1 173 ? 66.610 104.986 44.255 1.00 37.22 ? 173 LEU A CD2 1 ATOM 1352 N N . ALA A 1 174 ? 64.142 102.865 39.975 1.00 36.82 ? 174 ALA A N 1 ATOM 1353 C CA . ALA A 1 174 ? 62.809 102.298 39.835 1.00 36.44 ? 174 ALA A CA 1 ATOM 1354 C C . ALA A 1 174 ? 62.810 100.895 39.155 1.00 37.51 ? 174 ALA A C 1 ATOM 1355 O O . ALA A 1 174 ? 61.952 100.038 39.488 1.00 37.68 ? 174 ALA A O 1 ATOM 1356 C CB . ALA A 1 174 ? 61.907 103.249 39.111 1.00 37.55 ? 174 ALA A CB 1 ATOM 1357 N N . LEU A 1 175 ? 63.716 100.674 38.190 1.00 37.18 ? 175 LEU A N 1 ATOM 1358 C CA . LEU A 1 175 ? 63.878 99.322 37.585 1.00 38.45 ? 175 LEU A CA 1 ATOM 1359 C C . LEU A 1 175 ? 64.293 98.297 38.682 1.00 38.28 ? 175 LEU A C 1 ATOM 1360 O O . LEU A 1 175 ? 63.805 97.165 38.700 1.00 37.30 ? 175 LEU A O 1 ATOM 1361 C CB . LEU A 1 175 ? 64.902 99.334 36.444 1.00 37.03 ? 175 LEU A CB 1 ATOM 1362 C CG . LEU A 1 175 ? 64.785 100.418 35.355 1.00 38.48 ? 175 LEU A CG 1 ATOM 1363 C CD1 . LEU A 1 175 ? 65.737 100.129 34.156 1.00 35.46 ? 175 LEU A CD1 1 ATOM 1364 C CD2 . LEU A 1 175 ? 63.357 100.615 34.863 1.00 39.23 ? 175 LEU A CD2 1 ATOM 1365 N N A GLN A 1 176 ? 65.203 98.706 39.571 0.50 38.54 ? 176 GLN A N 1 ATOM 1366 N N B GLN A 1 176 ? 65.189 98.750 39.559 0.50 38.41 ? 176 GLN A N 1 ATOM 1367 C CA A GLN A 1 176 ? 65.598 97.889 40.723 0.50 39.52 ? 176 GLN A CA 1 ATOM 1368 C CA B GLN A 1 176 ? 65.663 98.049 40.748 0.50 39.23 ? 176 GLN A CA 1 ATOM 1369 C C A GLN A 1 176 ? 64.412 97.619 41.635 0.50 39.74 ? 176 GLN A C 1 ATOM 1370 C C B GLN A 1 176 ? 64.509 97.692 41.679 0.50 39.59 ? 176 GLN A C 1 ATOM 1371 O O A GLN A 1 176 ? 64.208 96.482 42.095 0.50 39.96 ? 176 GLN A O 1 ATOM 1372 O O B GLN A 1 176 ? 64.427 96.566 42.188 0.50 40.05 ? 176 GLN A O 1 ATOM 1373 C CB A GLN A 1 176 ? 66.734 98.540 41.525 0.50 40.06 ? 176 GLN A CB 1 ATOM 1374 C CB B GLN A 1 176 ? 66.649 98.975 41.467 0.50 39.66 ? 176 GLN A CB 1 ATOM 1375 C CG A GLN A 1 176 ? 68.111 97.854 41.394 0.50 42.72 ? 176 GLN A CG 1 ATOM 1376 C CG B GLN A 1 176 ? 67.505 98.369 42.553 0.50 40.96 ? 176 GLN A CG 1 ATOM 1377 C CD A GLN A 1 176 ? 68.136 96.416 41.933 0.50 45.48 ? 176 GLN A CD 1 ATOM 1378 C CD B GLN A 1 176 ? 68.796 99.149 42.727 0.50 44.34 ? 176 GLN A CD 1 ATOM 1379 O OE1 A GLN A 1 176 ? 68.863 95.571 41.417 0.50 47.29 ? 176 GLN A OE1 1 ATOM 1380 O OE1 B GLN A 1 176 ? 69.438 99.546 41.733 0.50 44.17 ? 176 GLN A OE1 1 ATOM 1381 N NE2 A GLN A 1 176 ? 67.331 96.142 42.958 0.50 46.90 ? 176 GLN A NE2 1 ATOM 1382 N NE2 B GLN A 1 176 ? 69.188 99.373 43.985 0.50 45.33 ? 176 GLN A NE2 1 ATOM 1383 N N . TRP A 1 177 ? 63.600 98.648 41.871 1.00 40.00 ? 177 TRP A N 1 ATOM 1384 C CA . TRP A 1 177 ? 62.414 98.472 42.738 1.00 39.80 ? 177 TRP A CA 1 ATOM 1385 C C . TRP A 1 177 ? 61.550 97.343 42.159 1.00 39.21 ? 177 TRP A C 1 ATOM 1386 O O . TRP A 1 177 ? 60.998 96.534 42.897 1.00 38.08 ? 177 TRP A O 1 ATOM 1387 C CB . TRP A 1 177 ? 61.610 99.787 42.861 1.00 39.65 ? 177 TRP A CB 1 ATOM 1388 C CG . TRP A 1 177 ? 60.417 99.665 43.776 1.00 40.40 ? 177 TRP A CG 1 ATOM 1389 C CD1 . TRP A 1 177 ? 60.365 100.002 45.123 1.00 41.12 ? 177 TRP A CD1 1 ATOM 1390 C CD2 . TRP A 1 177 ? 59.116 99.145 43.451 1.00 38.78 ? 177 TRP A CD2 1 ATOM 1391 N NE1 . TRP A 1 177 ? 59.121 99.701 45.635 1.00 39.14 ? 177 TRP A NE1 1 ATOM 1392 C CE2 . TRP A 1 177 ? 58.324 99.212 44.632 1.00 38.58 ? 177 TRP A CE2 1 ATOM 1393 C CE3 . TRP A 1 177 ? 58.520 98.648 42.273 1.00 39.41 ? 177 TRP A CE3 1 ATOM 1394 C CZ2 . TRP A 1 177 ? 56.985 98.774 44.674 1.00 37.46 ? 177 TRP A CZ2 1 ATOM 1395 C CZ3 . TRP A 1 177 ? 57.197 98.223 42.306 1.00 36.09 ? 177 TRP A CZ3 1 ATOM 1396 C CH2 . TRP A 1 177 ? 56.443 98.276 43.510 1.00 38.99 ? 177 TRP A CH2 1 ATOM 1397 N N . VAL A 1 178 ? 61.399 97.326 40.829 1.00 38.71 ? 178 VAL A N 1 ATOM 1398 C CA . VAL A 1 178 ? 60.622 96.272 40.174 1.00 38.72 ? 178 VAL A CA 1 ATOM 1399 C C . VAL A 1 178 ? 61.288 94.891 40.376 1.00 39.42 ? 178 VAL A C 1 ATOM 1400 O O . VAL A 1 178 ? 60.615 93.909 40.659 1.00 39.45 ? 178 VAL A O 1 ATOM 1401 C CB . VAL A 1 178 ? 60.399 96.565 38.644 1.00 39.28 ? 178 VAL A CB 1 ATOM 1402 C CG1 . VAL A 1 178 ? 59.824 95.369 37.932 1.00 36.55 ? 178 VAL A CG1 1 ATOM 1403 C CG2 . VAL A 1 178 ? 59.495 97.774 38.434 1.00 38.25 ? 178 VAL A CG2 1 ATOM 1404 N N . GLN A 1 179 ? 62.607 94.822 40.197 1.00 40.76 ? 179 GLN A N 1 ATOM 1405 C CA . GLN A 1 179 ? 63.353 93.572 40.403 1.00 41.86 ? 179 GLN A CA 1 ATOM 1406 C C . GLN A 1 179 ? 63.033 93.041 41.834 1.00 42.79 ? 179 GLN A C 1 ATOM 1407 O O . GLN A 1 179 ? 62.559 91.895 41.994 1.00 41.69 ? 179 GLN A O 1 ATOM 1408 C CB . GLN A 1 179 ? 64.865 93.770 40.168 1.00 41.26 ? 179 GLN A CB 1 ATOM 1409 C CG . GLN A 1 179 ? 65.296 93.802 38.685 1.00 42.06 ? 179 GLN A CG 1 ATOM 1410 C CD . GLN A 1 179 ? 64.750 92.607 37.895 1.00 43.14 ? 179 GLN A CD 1 ATOM 1411 O OE1 . GLN A 1 179 ? 65.263 91.508 38.027 1.00 43.29 ? 179 GLN A OE1 1 ATOM 1412 N NE2 . GLN A 1 179 ? 63.691 92.815 37.123 1.00 41.96 ? 179 GLN A NE2 1 ATOM 1413 N N . LYS A 1 180 ? 63.244 93.901 42.841 1.00 43.09 ? 180 LYS A N 1 ATOM 1414 C CA . LYS A 1 180 ? 62.973 93.550 44.255 1.00 44.30 ? 180 LYS A CA 1 ATOM 1415 C C . LYS A 1 180 ? 61.506 93.284 44.647 1.00 43.91 ? 180 LYS A C 1 ATOM 1416 O O . LYS A 1 180 ? 61.237 92.426 45.484 1.00 44.88 ? 180 LYS A O 1 ATOM 1417 C CB . LYS A 1 180 ? 63.606 94.589 45.166 1.00 44.34 ? 180 LYS A CB 1 ATOM 1418 C CG . LYS A 1 180 ? 65.080 94.393 45.224 1.00 49.16 ? 180 LYS A CG 1 ATOM 1419 C CD . LYS A 1 180 ? 65.857 95.709 45.221 1.00 57.76 ? 180 LYS A CD 1 ATOM 1420 C CE . LYS A 1 180 ? 66.280 96.166 46.624 1.00 60.45 ? 180 LYS A CE 1 ATOM 1421 N NZ . LYS A 1 180 ? 67.613 96.831 46.537 1.00 64.69 ? 180 LYS A NZ 1 ATOM 1422 N N . ASN A 1 181 ? 60.553 93.965 44.020 1.00 43.19 ? 181 ASN A N 1 ATOM 1423 C CA . ASN A 1 181 ? 59.215 94.008 44.570 1.00 42.33 ? 181 ASN A CA 1 ATOM 1424 C C . ASN A 1 181 ? 58.106 93.449 43.706 1.00 41.68 ? 181 ASN A C 1 ATOM 1425 O O . ASN A 1 181 ? 57.034 93.147 44.223 1.00 40.78 ? 181 ASN A O 1 ATOM 1426 C CB . ASN A 1 181 ? 58.856 95.459 44.981 1.00 42.04 ? 181 ASN A CB 1 ATOM 1427 C CG . ASN A 1 181 ? 59.783 96.002 46.018 1.00 43.32 ? 181 ASN A CG 1 ATOM 1428 O OD1 . ASN A 1 181 ? 59.668 95.663 47.188 1.00 46.83 ? 181 ASN A OD1 1 ATOM 1429 N ND2 . ASN A 1 181 ? 60.724 96.853 45.608 1.00 43.35 ? 181 ASN A ND2 1 ATOM 1430 N N . ILE A 1 182 ? 58.323 93.332 42.401 1.00 40.62 ? 182 ILE A N 1 ATOM 1431 C CA . ILE A 1 182 ? 57.200 92.959 41.531 1.00 40.27 ? 182 ILE A CA 1 ATOM 1432 C C . ILE A 1 182 ? 56.647 91.518 41.686 1.00 40.87 ? 182 ILE A C 1 ATOM 1433 O O . ILE A 1 182 ? 55.498 91.270 41.338 1.00 41.58 ? 182 ILE A O 1 ATOM 1434 C CB . ILE A 1 182 ? 57.526 93.314 40.024 1.00 40.82 ? 182 ILE A CB 1 ATOM 1435 C CG1 . ILE A 1 182 ? 56.281 93.791 39.279 1.00 39.30 ? 182 ILE A CG1 1 ATOM 1436 C CG2 . ILE A 1 182 ? 58.265 92.170 39.317 1.00 38.79 ? 182 ILE A CG2 1 ATOM 1437 C CD1 . ILE A 1 182 ? 55.849 95.200 39.691 1.00 40.62 ? 182 ILE A CD1 1 ATOM 1438 N N . ALA A 1 183 ? 57.429 90.559 42.177 1.00 42.25 ? 183 ALA A N 1 ATOM 1439 C CA . ALA A 1 183 ? 56.867 89.196 42.399 1.00 42.66 ? 183 ALA A CA 1 ATOM 1440 C C . ALA A 1 183 ? 55.726 89.229 43.407 1.00 43.45 ? 183 ALA A C 1 ATOM 1441 O O . ALA A 1 183 ? 54.758 88.496 43.266 1.00 43.52 ? 183 ALA A O 1 ATOM 1442 C CB . ALA A 1 183 ? 57.935 88.244 42.849 1.00 43.15 ? 183 ALA A CB 1 ATOM 1443 N N . ALA A 1 184 ? 55.807 90.141 44.375 1.00 44.01 ? 184 ALA A N 1 ATOM 1444 C CA . ALA A 1 184 ? 54.747 90.314 45.380 1.00 44.92 ? 184 ALA A CA 1 ATOM 1445 C C . ALA A 1 184 ? 53.421 90.774 44.760 1.00 45.90 ? 184 ALA A C 1 ATOM 1446 O O . ALA A 1 184 ? 52.325 90.563 45.318 1.00 47.27 ? 184 ALA A O 1 ATOM 1447 C CB . ALA A 1 184 ? 55.214 91.272 46.452 1.00 44.84 ? 184 ALA A CB 1 ATOM 1448 N N . PHE A 1 185 ? 53.509 91.367 43.575 1.00 45.29 ? 185 PHE A N 1 ATOM 1449 C CA . PHE A 1 185 ? 52.332 91.812 42.858 1.00 44.25 ? 185 PHE A CA 1 ATOM 1450 C C . PHE A 1 185 ? 51.918 90.792 41.811 1.00 44.06 ? 185 PHE A C 1 ATOM 1451 O O . PHE A 1 185 ? 51.000 91.039 41.064 1.00 43.90 ? 185 PHE A O 1 ATOM 1452 C CB . PHE A 1 185 ? 52.601 93.152 42.152 1.00 44.40 ? 185 PHE A CB 1 ATOM 1453 C CG . PHE A 1 185 ? 52.815 94.316 43.091 1.00 42.73 ? 185 PHE A CG 1 ATOM 1454 C CD1 . PHE A 1 185 ? 54.067 94.538 43.670 1.00 40.01 ? 185 PHE A CD1 1 ATOM 1455 C CD2 . PHE A 1 185 ? 51.764 95.188 43.386 1.00 38.62 ? 185 PHE A CD2 1 ATOM 1456 C CE1 . PHE A 1 185 ? 54.267 95.613 44.539 1.00 42.12 ? 185 PHE A CE1 1 ATOM 1457 C CE2 . PHE A 1 185 ? 51.948 96.252 44.270 1.00 40.74 ? 185 PHE A CE2 1 ATOM 1458 C CZ . PHE A 1 185 ? 53.196 96.486 44.833 1.00 41.55 ? 185 PHE A CZ 1 ATOM 1459 N N . GLY A 1 186 ? 52.596 89.648 41.762 1.00 44.17 ? 186 GLY A N 1 ATOM 1460 C CA . GLY A 1 186 ? 52.308 88.628 40.758 1.00 43.06 ? 186 GLY A CA 1 ATOM 1461 C C . GLY A 1 186 ? 53.050 88.794 39.432 1.00 42.86 ? 186 GLY A C 1 ATOM 1462 O O . GLY A 1 186 ? 52.671 88.200 38.422 1.00 42.07 ? 186 GLY A O 1 ATOM 1463 N N . GLY A 1 187 ? 54.113 89.595 39.439 1.00 42.46 ? 187 GLY A N 1 ATOM 1464 C CA . GLY A 1 187 ? 54.838 89.932 38.220 1.00 41.34 ? 187 GLY A CA 1 ATOM 1465 C C . GLY A 1 187 ? 56.112 89.123 38.170 1.00 41.49 ? 187 GLY A C 1 ATOM 1466 O O . GLY A 1 187 ? 56.622 88.714 39.198 1.00 41.42 ? 187 GLY A O 1 ATOM 1467 N N . ASN A 1 188 ? 56.630 88.885 36.967 1.00 40.38 ? 188 ASN A N 1 ATOM 1468 C CA . ASN A 1 188 ? 57.893 88.173 36.803 1.00 38.94 ? 188 ASN A CA 1 ATOM 1469 C C . ASN A 1 188 ? 59.088 89.126 36.554 1.00 39.13 ? 188 ASN A C 1 ATOM 1470 O O . ASN A 1 188 ? 59.207 89.651 35.470 1.00 38.86 ? 188 ASN A O 1 ATOM 1471 C CB . ASN A 1 188 ? 57.723 87.209 35.617 1.00 38.71 ? 188 ASN A CB 1 ATOM 1472 C CG . ASN A 1 188 ? 58.945 86.383 35.337 1.00 35.58 ? 188 ASN A CG 1 ATOM 1473 O OD1 . ASN A 1 188 ? 59.922 86.402 36.071 1.00 40.87 ? 188 ASN A OD1 1 ATOM 1474 N ND2 . ASN A 1 188 ? 58.893 85.652 34.273 1.00 34.59 ? 188 ASN A ND2 1 ATOM 1475 N N . PRO A 1 189 ? 59.995 89.296 37.519 1.00 39.68 ? 189 PRO A N 1 ATOM 1476 C CA . PRO A 1 189 ? 61.167 90.150 37.324 1.00 40.09 ? 189 PRO A CA 1 ATOM 1477 C C . PRO A 1 189 ? 62.096 89.702 36.186 1.00 40.91 ? 189 PRO A C 1 ATOM 1478 O O . PRO A 1 189 ? 62.921 90.500 35.712 1.00 41.34 ? 189 PRO A O 1 ATOM 1479 C CB . PRO A 1 189 ? 61.917 90.034 38.662 1.00 40.45 ? 189 PRO A CB 1 ATOM 1480 C CG . PRO A 1 189 ? 61.410 88.774 39.284 1.00 40.05 ? 189 PRO A CG 1 ATOM 1481 C CD . PRO A 1 189 ? 59.976 88.693 38.870 1.00 39.26 ? 189 PRO A CD 1 ATOM 1482 N N . LYS A 1 190 ? 61.965 88.450 35.748 1.00 40.71 ? 190 LYS A N 1 ATOM 1483 C CA . LYS A 1 190 ? 62.784 87.919 34.651 1.00 40.40 ? 190 LYS A CA 1 ATOM 1484 C C . LYS A 1 190 ? 62.176 88.185 33.273 1.00 39.08 ? 190 LYS A C 1 ATOM 1485 O O . LYS A 1 190 ? 62.815 87.882 32.245 1.00 38.19 ? 190 LYS A O 1 ATOM 1486 C CB . LYS A 1 190 ? 62.976 86.400 34.825 1.00 41.66 ? 190 LYS A CB 1 ATOM 1487 C CG . LYS A 1 190 ? 63.980 86.041 35.913 1.00 43.98 ? 190 LYS A CG 1 ATOM 1488 C CD . LYS A 1 190 ? 64.002 84.513 36.146 1.00 51.79 ? 190 LYS A CD 1 ATOM 1489 C CE . LYS A 1 190 ? 63.989 84.201 37.648 1.00 55.57 ? 190 LYS A CE 1 ATOM 1490 N NZ . LYS A 1 190 ? 64.871 83.024 37.972 1.00 61.73 ? 190 LYS A NZ 1 ATOM 1491 N N . SER A 1 191 ? 60.950 88.734 33.252 1.00 36.78 ? 191 SER A N 1 ATOM 1492 C CA . SER A 1 191 ? 60.246 89.086 31.991 1.00 34.99 ? 191 SER A CA 1 ATOM 1493 C C . SER A 1 191 ? 59.794 90.579 32.075 1.00 34.68 ? 191 SER A C 1 ATOM 1494 O O . SER A 1 191 ? 58.610 90.904 32.304 1.00 35.07 ? 191 SER A O 1 ATOM 1495 C CB . SER A 1 191 ? 59.097 88.141 31.722 1.00 33.18 ? 191 SER A CB 1 ATOM 1496 O OG . SER A 1 191 ? 58.445 88.375 30.466 1.00 35.81 ? 191 SER A OG 1 ATOM 1497 N N . VAL A 1 192 ? 60.766 91.465 31.882 1.00 33.71 ? 192 VAL A N 1 ATOM 1498 C CA . VAL A 1 192 ? 60.565 92.903 32.001 1.00 33.65 ? 192 VAL A CA 1 ATOM 1499 C C . VAL A 1 192 ? 60.942 93.592 30.699 1.00 32.50 ? 192 VAL A C 1 ATOM 1500 O O . VAL A 1 192 ? 62.102 93.565 30.297 1.00 32.17 ? 192 VAL A O 1 ATOM 1501 C CB . VAL A 1 192 ? 61.408 93.487 33.158 1.00 33.60 ? 192 VAL A CB 1 ATOM 1502 C CG1 . VAL A 1 192 ? 61.282 95.065 33.215 1.00 34.47 ? 192 VAL A CG1 1 ATOM 1503 C CG2 . VAL A 1 192 ? 60.966 92.869 34.475 1.00 35.58 ? 192 VAL A CG2 1 ATOM 1504 N N . THR A 1 193 ? 59.968 94.235 30.068 1.00 31.91 ? 193 THR A N 1 ATOM 1505 C CA . THR A 1 193 ? 60.246 95.049 28.901 1.00 31.67 ? 193 THR A CA 1 ATOM 1506 C C . THR A 1 193 ? 60.158 96.556 29.178 1.00 31.50 ? 193 THR A C 1 ATOM 1507 O O . THR A 1 193 ? 59.162 97.017 29.685 1.00 31.57 ? 193 THR A O 1 ATOM 1508 C CB . THR A 1 193 ? 59.292 94.634 27.800 1.00 31.39 ? 193 THR A CB 1 ATOM 1509 O OG1 . THR A 1 193 ? 59.610 93.280 27.487 1.00 32.22 ? 193 THR A OG1 1 ATOM 1510 C CG2 . THR A 1 193 ? 59.560 95.415 26.469 1.00 29.13 ? 193 THR A CG2 1 ATOM 1511 N N . LEU A 1 194 ? 61.217 97.304 28.867 1.00 31.61 ? 194 LEU A N 1 ATOM 1512 C CA . LEU A 1 194 ? 61.147 98.773 28.940 1.00 30.69 ? 194 LEU A CA 1 ATOM 1513 C C . LEU A 1 194 ? 60.521 99.241 27.652 1.00 31.29 ? 194 LEU A C 1 ATOM 1514 O O . LEU A 1 194 ? 60.813 98.671 26.580 1.00 30.75 ? 194 LEU A O 1 ATOM 1515 C CB . LEU A 1 194 ? 62.549 99.388 29.068 1.00 29.69 ? 194 LEU A CB 1 ATOM 1516 C CG . LEU A 1 194 ? 63.481 98.828 30.159 1.00 30.52 ? 194 LEU A CG 1 ATOM 1517 C CD1 . LEU A 1 194 ? 64.870 99.518 30.170 1.00 29.94 ? 194 LEU A CD1 1 ATOM 1518 C CD2 . LEU A 1 194 ? 62.863 98.780 31.598 1.00 28.41 ? 194 LEU A CD2 1 ATOM 1519 N N . PHE A 1 195 ? 59.641 100.244 27.749 1.00 31.84 ? 195 PHE A N 1 ATOM 1520 C CA . PHE A 1 195 ? 59.152 100.950 26.578 1.00 31.55 ? 195 PHE A CA 1 ATOM 1521 C C . PHE A 1 195 ? 59.069 102.424 26.928 1.00 33.20 ? 195 PHE A C 1 ATOM 1522 O O . PHE A 1 195 ? 58.941 102.773 28.118 1.00 32.85 ? 195 PHE A O 1 ATOM 1523 C CB . PHE A 1 195 ? 57.900 100.301 25.947 1.00 30.66 ? 195 PHE A CB 1 ATOM 1524 C CG . PHE A 1 195 ? 56.617 100.419 26.733 1.00 30.93 ? 195 PHE A CG 1 ATOM 1525 C CD1 . PHE A 1 195 ? 56.567 100.224 28.104 1.00 30.97 ? 195 PHE A CD1 1 ATOM 1526 C CD2 . PHE A 1 195 ? 55.433 100.662 26.062 1.00 30.58 ? 195 PHE A CD2 1 ATOM 1527 C CE1 . PHE A 1 195 ? 55.373 100.334 28.769 1.00 30.18 ? 195 PHE A CE1 1 ATOM 1528 C CE2 . PHE A 1 195 ? 54.261 100.776 26.729 1.00 31.93 ? 195 PHE A CE2 1 ATOM 1529 C CZ . PHE A 1 195 ? 54.231 100.597 28.107 1.00 29.96 ? 195 PHE A CZ 1 ATOM 1530 N N . GLY A 1 196 ? 59.301 103.284 25.924 1.00 32.98 ? 196 GLY A N 1 ATOM 1531 C CA . GLY A 1 196 ? 59.367 104.702 26.154 1.00 31.60 ? 196 GLY A CA 1 ATOM 1532 C C . GLY A 1 196 ? 59.224 105.387 24.831 1.00 32.15 ? 196 GLY A C 1 ATOM 1533 O O . GLY A 1 196 ? 59.434 104.753 23.798 1.00 32.44 ? 196 GLY A O 1 ATOM 1534 N N . GLU A 1 197 ? 58.872 106.678 24.851 1.00 31.52 ? 197 GLU A N 1 ATOM 1535 C CA . GLU A 1 197 ? 58.741 107.477 23.621 1.00 31.13 ? 197 GLU A CA 1 ATOM 1536 C C . GLU A 1 197 ? 59.598 108.731 23.705 1.00 31.16 ? 197 GLU A C 1 ATOM 1537 O O . GLU A 1 197 ? 59.763 109.309 24.801 1.00 31.67 ? 197 GLU A O 1 ATOM 1538 C CB . GLU A 1 197 ? 57.260 107.782 23.282 1.00 30.58 ? 197 GLU A CB 1 ATOM 1539 C CG . GLU A 1 197 ? 57.029 108.528 21.954 1.00 29.67 ? 197 GLU A CG 1 ATOM 1540 C CD . GLU A 1 197 ? 57.001 110.055 22.118 1.00 33.30 ? 197 GLU A CD 1 ATOM 1541 O OE1 . GLU A 1 197 ? 57.079 110.521 23.291 1.00 31.92 ? 197 GLU A OE1 1 ATOM 1542 O OE2 . GLU A 1 197 ? 56.886 110.790 21.091 1.00 29.43 ? 197 GLU A OE2 1 ATOM 1543 N N . SER A 1 198 ? 60.168 109.102 22.551 1.00 31.48 ? 198 SER A N 1 ATOM 1544 C CA . SER A 1 198 ? 61.100 110.229 22.367 1.00 31.73 ? 198 SER A CA 1 ATOM 1545 C C . SER A 1 198 ? 62.255 110.154 23.375 1.00 31.94 ? 198 SER A C 1 ATOM 1546 O O . SER A 1 198 ? 62.987 109.167 23.359 1.00 33.94 ? 198 SER A O 1 ATOM 1547 C CB . SER A 1 198 ? 60.355 111.573 22.386 1.00 32.91 ? 198 SER A CB 1 ATOM 1548 O OG . SER A 1 198 ? 60.984 112.826 22.027 1.00 47.55 ? 198 SER A OG 1 ATOM 1549 N N . ALA A 1 199 ? 62.384 111.129 24.291 1.00 30.82 ? 199 ALA A N 1 ATOM 1550 C CA . ALA A 1 199 ? 63.410 111.062 25.345 1.00 30.04 ? 199 ALA A CA 1 ATOM 1551 C C . ALA A 1 199 ? 63.260 109.842 26.211 1.00 29.39 ? 199 ALA A C 1 ATOM 1552 O O . ALA A 1 199 ? 64.239 109.391 26.804 1.00 29.65 ? 199 ALA A O 1 ATOM 1553 C CB . ALA A 1 199 ? 63.412 112.357 26.256 1.00 29.37 ? 199 ALA A CB 1 ATOM 1554 N N . GLY A 1 200 ? 62.032 109.334 26.358 1.00 29.08 ? 200 GLY A N 1 ATOM 1555 C CA . GLY A 1 200 ? 61.860 108.086 27.081 1.00 28.98 ? 200 GLY A CA 1 ATOM 1556 C C . GLY A 1 200 ? 62.459 106.926 26.283 1.00 28.98 ? 200 GLY A C 1 ATOM 1557 O O . GLY A 1 200 ? 63.013 106.025 26.852 1.00 29.36 ? 200 GLY A O 1 ATOM 1558 N N . ALA A 1 201 ? 62.322 106.961 24.954 1.00 30.13 ? 201 ALA A N 1 ATOM 1559 C CA . ALA A 1 201 ? 62.951 105.968 24.034 1.00 30.00 ? 201 ALA A CA 1 ATOM 1560 C C . ALA A 1 201 ? 64.463 106.106 24.032 1.00 30.89 ? 201 ALA A C 1 ATOM 1561 O O . ALA A 1 201 ? 65.176 105.103 24.116 1.00 30.46 ? 201 ALA A O 1 ATOM 1562 C CB . ALA A 1 201 ? 62.406 106.113 22.590 1.00 29.00 ? 201 ALA A CB 1 ATOM 1563 N N . ALA A 1 202 ? 64.968 107.343 23.910 1.00 30.82 ? 202 ALA A N 1 ATOM 1564 C CA . ALA A 1 202 ? 66.409 107.565 24.113 1.00 30.89 ? 202 ALA A CA 1 ATOM 1565 C C . ALA A 1 202 ? 66.882 107.027 25.505 1.00 31.57 ? 202 ALA A C 1 ATOM 1566 O O . ALA A 1 202 ? 67.967 106.390 25.633 1.00 32.05 ? 202 ALA A O 1 ATOM 1567 C CB . ALA A 1 202 ? 66.730 109.067 23.967 1.00 31.50 ? 202 ALA A CB 1 ATOM 1568 N N . SER A 1 203 ? 66.075 107.240 26.538 1.00 30.15 ? 203 SER A N 1 ATOM 1569 C CA . SER A 1 203 ? 66.407 106.698 27.856 1.00 31.03 ? 203 SER A CA 1 ATOM 1570 C C . SER A 1 203 ? 66.491 105.157 27.798 1.00 31.45 ? 203 SER A C 1 ATOM 1571 O O . SER A 1 203 ? 67.440 104.557 28.246 1.00 31.36 ? 203 SER A O 1 ATOM 1572 C CB . SER A 1 203 ? 65.345 107.109 28.873 1.00 30.42 ? 203 SER A CB 1 ATOM 1573 O OG . SER A 1 203 ? 65.368 108.527 29.095 1.00 34.92 ? 203 SER A OG 1 ATOM 1574 N N . VAL A 1 204 ? 65.480 104.526 27.218 1.00 31.54 ? 204 VAL A N 1 ATOM 1575 C CA . VAL A 1 204 ? 65.507 103.071 27.040 1.00 32.02 ? 204 VAL A CA 1 ATOM 1576 C C . VAL A 1 204 ? 66.814 102.646 26.339 1.00 31.59 ? 204 VAL A C 1 ATOM 1577 O O . VAL A 1 204 ? 67.480 101.726 26.787 1.00 31.57 ? 204 VAL A O 1 ATOM 1578 C CB . VAL A 1 204 ? 64.224 102.531 26.272 1.00 31.69 ? 204 VAL A CB 1 ATOM 1579 C CG1 . VAL A 1 204 ? 64.423 101.079 25.711 1.00 31.03 ? 204 VAL A CG1 1 ATOM 1580 C CG2 . VAL A 1 204 ? 63.015 102.560 27.192 1.00 30.61 ? 204 VAL A CG2 1 ATOM 1581 N N . SER A 1 205 ? 67.192 103.351 25.287 1.00 32.29 ? 205 SER A N 1 ATOM 1582 C CA . SER A 1 205 ? 68.385 102.963 24.528 1.00 33.40 ? 205 SER A CA 1 ATOM 1583 C C . SER A 1 205 ? 69.687 103.074 25.363 1.00 34.19 ? 205 SER A C 1 ATOM 1584 O O . SER A 1 205 ? 70.619 102.281 25.172 1.00 35.22 ? 205 SER A O 1 ATOM 1585 C CB . SER A 1 205 ? 68.463 103.695 23.177 1.00 31.73 ? 205 SER A CB 1 ATOM 1586 O OG . SER A 1 205 ? 68.792 105.065 23.326 1.00 33.48 ? 205 SER A OG 1 ATOM 1587 N N . LEU A 1 206 ? 69.727 104.028 26.294 1.00 33.74 ? 206 LEU A N 1 ATOM 1588 C CA . LEU A 1 206 ? 70.871 104.210 27.212 1.00 33.19 ? 206 LEU A CA 1 ATOM 1589 C C . LEU A 1 206 ? 70.954 103.130 28.308 1.00 33.14 ? 206 LEU A C 1 ATOM 1590 O O . LEU A 1 206 ? 72.031 102.815 28.789 1.00 32.64 ? 206 LEU A O 1 ATOM 1591 C CB . LEU A 1 206 ? 70.796 105.624 27.860 1.00 33.24 ? 206 LEU A CB 1 ATOM 1592 C CG . LEU A 1 206 ? 71.094 106.748 26.862 1.00 31.37 ? 206 LEU A CG 1 ATOM 1593 C CD1 . LEU A 1 206 ? 70.767 108.125 27.397 1.00 33.57 ? 206 LEU A CD1 1 ATOM 1594 C CD2 . LEU A 1 206 ? 72.564 106.673 26.354 1.00 29.57 ? 206 LEU A CD2 1 ATOM 1595 N N . HIS A 1 207 ? 69.809 102.640 28.760 1.00 32.82 ? 207 HIS A N 1 ATOM 1596 C CA . HIS A 1 207 ? 69.755 101.491 29.650 1.00 33.85 ? 207 HIS A CA 1 ATOM 1597 C C . HIS A 1 207 ? 70.321 100.217 28.991 1.00 35.67 ? 207 HIS A C 1 ATOM 1598 O O . HIS A 1 207 ? 70.860 99.395 29.691 1.00 36.02 ? 207 HIS A O 1 ATOM 1599 C CB . HIS A 1 207 ? 68.309 101.262 30.112 1.00 34.20 ? 207 HIS A CB 1 ATOM 1600 C CG . HIS A 1 207 ? 67.845 102.263 31.148 1.00 35.50 ? 207 HIS A CG 1 ATOM 1601 N ND1 . HIS A 1 207 ? 68.295 102.250 32.455 1.00 34.10 ? 207 HIS A ND1 1 ATOM 1602 C CD2 . HIS A 1 207 ? 66.981 103.305 31.059 1.00 33.04 ? 207 HIS A CD2 1 ATOM 1603 C CE1 . HIS A 1 207 ? 67.724 103.238 33.126 1.00 37.68 ? 207 HIS A CE1 1 ATOM 1604 N NE2 . HIS A 1 207 ? 66.914 103.888 32.304 1.00 32.95 ? 207 HIS A NE2 1 ATOM 1605 N N . LEU A 1 208 ? 70.182 100.080 27.656 1.00 35.88 ? 208 LEU A N 1 ATOM 1606 C CA . LEU A 1 208 ? 70.840 99.046 26.884 1.00 36.79 ? 208 LEU A CA 1 ATOM 1607 C C . LEU A 1 208 ? 72.368 99.170 26.937 1.00 37.37 ? 208 LEU A C 1 ATOM 1608 O O . LEU A 1 208 ? 73.070 98.168 26.835 1.00 37.86 ? 208 LEU A O 1 ATOM 1609 C CB . LEU A 1 208 ? 70.379 99.075 25.405 1.00 35.18 ? 208 LEU A CB 1 ATOM 1610 C CG . LEU A 1 208 ? 68.940 98.596 25.126 1.00 35.18 ? 208 LEU A CG 1 ATOM 1611 C CD1 . LEU A 1 208 ? 68.529 98.932 23.661 1.00 29.66 ? 208 LEU A CD1 1 ATOM 1612 C CD2 . LEU A 1 208 ? 68.746 97.084 25.446 1.00 31.64 ? 208 LEU A CD2 1 ATOM 1613 N N . LEU A 1 209 ? 72.869 100.393 27.082 1.00 37.86 ? 209 LEU A N 1 ATOM 1614 C CA . LEU A 1 209 ? 74.286 100.645 27.175 1.00 38.41 ? 209 LEU A CA 1 ATOM 1615 C C . LEU A 1 209 ? 74.825 100.659 28.587 1.00 39.47 ? 209 LEU A C 1 ATOM 1616 O O . LEU A 1 209 ? 76.018 100.491 28.769 1.00 41.53 ? 209 LEU A O 1 ATOM 1617 C CB . LEU A 1 209 ? 74.660 101.968 26.528 1.00 39.07 ? 209 LEU A CB 1 ATOM 1618 C CG . LEU A 1 209 ? 74.249 102.269 25.087 1.00 40.87 ? 209 LEU A CG 1 ATOM 1619 C CD1 . LEU A 1 209 ? 75.039 103.428 24.535 1.00 42.39 ? 209 LEU A CD1 1 ATOM 1620 C CD2 . LEU A 1 209 ? 74.417 101.120 24.207 1.00 40.62 ? 209 LEU A CD2 1 ATOM 1621 N N . SER A 1 210 ? 73.992 100.896 29.588 1.00 39.65 ? 210 SER A N 1 ATOM 1622 C CA . SER A 1 210 ? 74.517 101.041 30.935 1.00 39.63 ? 210 SER A CA 1 ATOM 1623 C C . SER A 1 210 ? 74.683 99.683 31.584 1.00 40.64 ? 210 SER A C 1 ATOM 1624 O O . SER A 1 210 ? 73.726 98.971 31.748 1.00 40.51 ? 210 SER A O 1 ATOM 1625 C CB . SER A 1 210 ? 73.597 101.905 31.801 1.00 39.65 ? 210 SER A CB 1 ATOM 1626 O OG . SER A 1 210 ? 74.293 102.263 32.992 1.00 39.87 ? 210 SER A OG 1 ATOM 1627 N N . PRO A 1 211 ? 75.901 99.332 31.988 1.00 42.55 ? 211 PRO A N 1 ATOM 1628 C CA . PRO A 1 211 ? 76.136 98.086 32.728 1.00 42.94 ? 211 PRO A CA 1 ATOM 1629 C C . PRO A 1 211 ? 75.287 97.926 33.996 1.00 42.30 ? 211 PRO A C 1 ATOM 1630 O O . PRO A 1 211 ? 74.853 96.805 34.287 1.00 42.89 ? 211 PRO A O 1 ATOM 1631 C CB . PRO A 1 211 ? 77.645 98.149 33.033 1.00 43.46 ? 211 PRO A CB 1 ATOM 1632 C CG . PRO A 1 211 ? 78.167 98.904 31.803 1.00 44.21 ? 211 PRO A CG 1 ATOM 1633 C CD . PRO A 1 211 ? 77.164 100.062 31.733 1.00 42.98 ? 211 PRO A CD 1 ATOM 1634 N N . GLY A 1 212 ? 75.022 99.023 34.706 1.00 41.47 ? 212 GLY A N 1 ATOM 1635 C CA . GLY A 1 212 ? 74.179 99.000 35.903 1.00 40.63 ? 212 GLY A CA 1 ATOM 1636 C C . GLY A 1 212 ? 72.713 98.672 35.606 1.00 41.13 ? 212 GLY A C 1 ATOM 1637 O O . GLY A 1 212 ? 71.971 98.252 36.476 1.00 41.18 ? 212 GLY A O 1 ATOM 1638 N N . SER A 1 213 ? 72.275 98.825 34.361 1.00 40.76 ? 213 SER A N 1 ATOM 1639 C CA . SER A 1 213 ? 70.910 98.428 34.029 1.00 39.90 ? 213 SER A CA 1 ATOM 1640 C C . SER A 1 213 ? 70.771 97.054 33.406 1.00 40.36 ? 213 SER A C 1 ATOM 1641 O O . SER A 1 213 ? 69.648 96.568 33.297 1.00 41.24 ? 213 SER A O 1 ATOM 1642 C CB . SER A 1 213 ? 70.229 99.487 33.140 1.00 39.66 ? 213 SER A CB 1 ATOM 1643 O OG . SER A 1 213 ? 70.262 100.763 33.787 1.00 39.73 ? 213 SER A OG 1 ATOM 1644 N N A HIS A 1 214 ? 71.895 96.440 32.999 0.50 40.54 ? 214 HIS A N 1 ATOM 1645 N N B HIS A 1 214 ? 71.865 96.425 32.994 0.50 40.30 ? 214 HIS A N 1 ATOM 1646 C CA A HIS A 1 214 ? 71.924 95.116 32.310 0.50 40.68 ? 214 HIS A CA 1 ATOM 1647 C CA B HIS A 1 214 ? 71.750 95.172 32.231 0.50 40.11 ? 214 HIS A CA 1 ATOM 1648 C C A HIS A 1 214 ? 70.941 94.101 32.888 0.50 40.87 ? 214 HIS A C 1 ATOM 1649 C C B HIS A 1 214 ? 70.911 94.064 32.881 0.50 40.58 ? 214 HIS A C 1 ATOM 1650 O O A HIS A 1 214 ? 70.094 93.568 32.180 0.50 40.83 ? 214 HIS A O 1 ATOM 1651 O O B HIS A 1 214 ? 70.109 93.428 32.206 0.50 40.47 ? 214 HIS A O 1 ATOM 1652 C CB A HIS A 1 214 ? 73.364 94.514 32.275 0.50 40.85 ? 214 HIS A CB 1 ATOM 1653 C CB B HIS A 1 214 ? 73.129 94.688 31.756 0.50 40.30 ? 214 HIS A CB 1 ATOM 1654 C CG A HIS A 1 214 ? 73.503 93.305 31.384 0.50 40.39 ? 214 HIS A CG 1 ATOM 1655 C CG B HIS A 1 214 ? 73.719 95.539 30.673 0.50 38.07 ? 214 HIS A CG 1 ATOM 1656 N ND1 A HIS A 1 214 ? 74.065 93.365 30.124 0.50 39.50 ? 214 HIS A ND1 1 ATOM 1657 N ND1 B HIS A 1 214 ? 73.047 96.615 30.115 0.50 36.08 ? 214 HIS A ND1 1 ATOM 1658 C CD2 A HIS A 1 214 ? 73.130 92.012 31.564 0.50 40.34 ? 214 HIS A CD2 1 ATOM 1659 C CD2 B HIS A 1 214 ? 74.911 95.460 30.030 0.50 37.34 ? 214 HIS A CD2 1 ATOM 1660 C CE1 A HIS A 1 214 ? 74.041 92.164 29.572 0.50 37.73 ? 214 HIS A CE1 1 ATOM 1661 C CE1 B HIS A 1 214 ? 73.813 97.161 29.184 0.50 36.46 ? 214 HIS A CE1 1 ATOM 1662 N NE2 A HIS A 1 214 ? 73.468 91.326 30.419 0.50 39.27 ? 214 HIS A NE2 1 ATOM 1663 N NE2 B HIS A 1 214 ? 74.945 96.475 29.108 0.50 33.78 ? 214 HIS A NE2 1 ATOM 1664 N N . SER A 1 215 ? 71.043 93.857 34.192 1.00 41.45 ? 215 SER A N 1 ATOM 1665 C CA . SER A 1 215 ? 70.271 92.794 34.856 1.00 41.79 ? 215 SER A CA 1 ATOM 1666 C C . SER A 1 215 ? 68.894 93.247 35.306 1.00 41.13 ? 215 SER A C 1 ATOM 1667 O O . SER A 1 215 ? 68.151 92.449 35.880 1.00 41.10 ? 215 SER A O 1 ATOM 1668 C CB . SER A 1 215 ? 71.053 92.253 36.062 1.00 43.81 ? 215 SER A CB 1 ATOM 1669 O OG . SER A 1 215 ? 71.198 93.289 37.042 1.00 48.74 ? 215 SER A OG 1 ATOM 1670 N N . LEU A 1 216 ? 68.529 94.514 35.025 1.00 39.67 ? 216 LEU A N 1 ATOM 1671 C CA . LEU A 1 216 ? 67.250 95.052 35.509 1.00 38.27 ? 216 LEU A CA 1 ATOM 1672 C C . LEU A 1 216 ? 66.109 94.976 34.509 1.00 38.36 ? 216 LEU A C 1 ATOM 1673 O O . LEU A 1 216 ? 65.005 95.463 34.788 1.00 38.20 ? 216 LEU A O 1 ATOM 1674 C CB . LEU A 1 216 ? 67.434 96.493 35.958 1.00 38.13 ? 216 LEU A CB 1 ATOM 1675 C CG . LEU A 1 216 ? 68.581 96.767 36.920 1.00 38.85 ? 216 LEU A CG 1 ATOM 1676 C CD1 . LEU A 1 216 ? 68.581 98.253 37.298 1.00 37.61 ? 216 LEU A CD1 1 ATOM 1677 C CD2 . LEU A 1 216 ? 68.544 95.834 38.168 1.00 37.72 ? 216 LEU A CD2 1 ATOM 1678 N N . PHE A 1 217 ? 66.387 94.430 33.312 1.00 36.93 ? 217 PHE A N 1 ATOM 1679 C CA . PHE A 1 217 ? 65.328 94.211 32.298 1.00 35.80 ? 217 PHE A CA 1 ATOM 1680 C C . PHE A 1 217 ? 65.674 93.145 31.240 1.00 35.55 ? 217 PHE A C 1 ATOM 1681 O O . PHE A 1 217 ? 66.819 92.754 31.121 1.00 35.55 ? 217 PHE A O 1 ATOM 1682 C CB . PHE A 1 217 ? 64.933 95.527 31.602 1.00 34.22 ? 217 PHE A CB 1 ATOM 1683 C CG . PHE A 1 217 ? 65.999 96.102 30.701 1.00 32.39 ? 217 PHE A CG 1 ATOM 1684 C CD1 . PHE A 1 217 ? 67.124 96.721 31.233 1.00 30.62 ? 217 PHE A CD1 1 ATOM 1685 C CD2 . PHE A 1 217 ? 65.829 96.089 29.299 1.00 29.28 ? 217 PHE A CD2 1 ATOM 1686 C CE1 . PHE A 1 217 ? 68.093 97.273 30.414 1.00 29.50 ? 217 PHE A CE1 1 ATOM 1687 C CE2 . PHE A 1 217 ? 66.799 96.595 28.471 1.00 27.70 ? 217 PHE A CE2 1 ATOM 1688 C CZ . PHE A 1 217 ? 67.917 97.236 29.014 1.00 30.30 ? 217 PHE A CZ 1 ATOM 1689 N N . THR A 1 218 ? 64.672 92.695 30.495 1.00 34.96 ? 218 THR A N 1 ATOM 1690 C CA . THR A 1 218 ? 64.851 91.644 29.499 1.00 35.54 ? 218 THR A CA 1 ATOM 1691 C C . THR A 1 218 ? 64.960 92.213 28.061 1.00 35.43 ? 218 THR A C 1 ATOM 1692 O O . THR A 1 218 ? 65.903 91.902 27.343 1.00 35.77 ? 218 THR A O 1 ATOM 1693 C CB . THR A 1 218 ? 63.636 90.723 29.546 1.00 36.34 ? 218 THR A CB 1 ATOM 1694 O OG1 . THR A 1 218 ? 63.367 90.323 30.918 1.00 36.66 ? 218 THR A OG1 1 ATOM 1695 C CG2 . THR A 1 218 ? 63.924 89.418 28.741 1.00 35.88 ? 218 THR A CG2 1 ATOM 1696 N N . ARG A 1 219 ? 63.976 93.016 27.653 1.00 33.70 ? 219 ARG A N 1 ATOM 1697 C CA . ARG A 1 219 ? 63.839 93.476 26.250 1.00 34.63 ? 219 ARG A CA 1 ATOM 1698 C C . ARG A 1 219 ? 63.535 94.990 26.248 1.00 32.75 ? 219 ARG A C 1 ATOM 1699 O O . ARG A 1 219 ? 63.273 95.556 27.321 1.00 32.40 ? 219 ARG A O 1 ATOM 1700 C CB . ARG A 1 219 ? 62.664 92.731 25.596 1.00 34.88 ? 219 ARG A CB 1 ATOM 1701 C CG . ARG A 1 219 ? 63.040 91.512 24.878 1.00 39.68 ? 219 ARG A CG 1 ATOM 1702 C CD . ARG A 1 219 ? 61.887 90.826 24.184 1.00 39.44 ? 219 ARG A CD 1 ATOM 1703 N NE . ARG A 1 219 ? 61.153 90.092 25.177 1.00 41.70 ? 219 ARG A NE 1 ATOM 1704 C CZ . ARG A 1 219 ? 61.484 88.901 25.620 1.00 40.65 ? 219 ARG A CZ 1 ATOM 1705 N NH1 . ARG A 1 219 ? 60.751 88.376 26.572 1.00 38.84 ? 219 ARG A NH1 1 ATOM 1706 N NH2 . ARG A 1 219 ? 62.535 88.232 25.122 1.00 38.47 ? 219 ARG A NH2 1 ATOM 1707 N N . ALA A 1 220 ? 63.522 95.613 25.062 1.00 31.06 ? 220 ALA A N 1 ATOM 1708 C CA . ALA A 1 220 ? 63.325 97.070 24.959 1.00 29.85 ? 220 ALA A CA 1 ATOM 1709 C C . ALA A 1 220 ? 62.535 97.467 23.725 1.00 30.27 ? 220 ALA A C 1 ATOM 1710 O O . ALA A 1 220 ? 62.685 96.861 22.653 1.00 30.49 ? 220 ALA A O 1 ATOM 1711 C CB . ALA A 1 220 ? 64.704 97.833 25.025 1.00 27.24 ? 220 ALA A CB 1 ATOM 1712 N N . ILE A 1 221 ? 61.686 98.489 23.879 1.00 30.86 ? 221 ILE A N 1 ATOM 1713 C CA . ILE A 1 221 ? 60.881 99.058 22.778 1.00 30.81 ? 221 ILE A CA 1 ATOM 1714 C C . ILE A 1 221 ? 61.200 100.537 22.723 1.00 31.24 ? 221 ILE A C 1 ATOM 1715 O O . ILE A 1 221 ? 61.138 101.232 23.752 1.00 31.47 ? 221 ILE A O 1 ATOM 1716 C CB . ILE A 1 221 ? 59.340 98.901 23.051 1.00 31.43 ? 221 ILE A CB 1 ATOM 1717 C CG1 . ILE A 1 221 ? 58.919 97.416 23.235 1.00 30.01 ? 221 ILE A CG1 1 ATOM 1718 C CG2 . ILE A 1 221 ? 58.494 99.665 21.971 1.00 30.25 ? 221 ILE A CG2 1 ATOM 1719 C CD1 . ILE A 1 221 ? 57.441 97.192 23.563 1.00 30.65 ? 221 ILE A CD1 1 ATOM 1720 N N . LEU A 1 222 ? 61.509 101.025 21.531 1.00 31.43 ? 222 LEU A N 1 ATOM 1721 C CA . LEU A 1 222 ? 61.911 102.421 21.329 1.00 32.50 ? 222 LEU A CA 1 ATOM 1722 C C . LEU A 1 222 ? 60.985 103.137 20.379 1.00 32.64 ? 222 LEU A C 1 ATOM 1723 O O . LEU A 1 222 ? 61.051 102.920 19.159 1.00 31.52 ? 222 LEU A O 1 ATOM 1724 C CB . LEU A 1 222 ? 63.347 102.502 20.802 1.00 31.91 ? 222 LEU A CB 1 ATOM 1725 C CG . LEU A 1 222 ? 64.489 102.135 21.764 1.00 35.36 ? 222 LEU A CG 1 ATOM 1726 C CD1 . LEU A 1 222 ? 64.447 100.640 22.048 1.00 36.03 ? 222 LEU A CD1 1 ATOM 1727 C CD2 . LEU A 1 222 ? 65.840 102.508 21.088 1.00 32.85 ? 222 LEU A CD2 1 ATOM 1728 N N . GLN A 1 223 ? 60.107 103.977 20.933 1.00 32.51 ? 223 GLN A N 1 ATOM 1729 C CA . GLN A 1 223 ? 59.177 104.740 20.081 1.00 31.77 ? 223 GLN A CA 1 ATOM 1730 C C . GLN A 1 223 ? 59.693 106.139 19.821 1.00 30.83 ? 223 GLN A C 1 ATOM 1731 O O . GLN A 1 223 ? 59.828 106.916 20.747 1.00 30.88 ? 223 GLN A O 1 ATOM 1732 C CB . GLN A 1 223 ? 57.764 104.759 20.680 1.00 32.20 ? 223 GLN A CB 1 ATOM 1733 C CG . GLN A 1 223 ? 57.224 103.318 21.009 1.00 32.45 ? 223 GLN A CG 1 ATOM 1734 C CD . GLN A 1 223 ? 55.958 103.254 21.882 1.00 33.39 ? 223 GLN A CD 1 ATOM 1735 O OE1 . GLN A 1 223 ? 55.721 102.244 22.515 1.00 33.79 ? 223 GLN A OE1 1 ATOM 1736 N NE2 . GLN A 1 223 ? 55.160 104.307 21.904 1.00 35.88 ? 223 GLN A NE2 1 ATOM 1737 N N . SER A 1 224 ? 59.982 106.462 18.553 1.00 30.69 ? 224 SER A N 1 ATOM 1738 C CA . SER A 1 224 ? 60.469 107.820 18.165 1.00 31.08 ? 224 SER A CA 1 ATOM 1739 C C . SER A 1 224 ? 61.581 108.355 19.059 1.00 31.63 ? 224 SER A C 1 ATOM 1740 O O . SER A 1 224 ? 61.458 109.473 19.587 1.00 31.72 ? 224 SER A O 1 ATOM 1741 C CB . SER A 1 224 ? 59.348 108.872 18.192 1.00 30.34 ? 224 SER A CB 1 ATOM 1742 O OG . SER A 1 224 ? 58.151 108.425 17.556 1.00 32.57 ? 224 SER A OG 1 ATOM 1743 N N . GLY A 1 225 ? 62.645 107.579 19.273 1.00 31.36 ? 225 GLY A N 1 ATOM 1744 C CA . GLY A 1 225 ? 63.827 108.147 19.935 1.00 30.99 ? 225 GLY A CA 1 ATOM 1745 C C . GLY A 1 225 ? 64.893 107.085 20.153 1.00 32.41 ? 225 GLY A C 1 ATOM 1746 O O . GLY A 1 225 ? 64.587 105.866 20.183 1.00 31.18 ? 225 GLY A O 1 ATOM 1747 N N . SER A 1 226 ? 66.140 107.550 20.299 1.00 32.49 ? 226 SER A N 1 ATOM 1748 C CA . SER A 1 226 ? 67.286 106.681 20.564 1.00 33.28 ? 226 SER A CA 1 ATOM 1749 C C . SER A 1 226 ? 68.401 107.645 20.917 1.00 33.66 ? 226 SER A C 1 ATOM 1750 O O . SER A 1 226 ? 68.374 108.808 20.471 1.00 33.47 ? 226 SER A O 1 ATOM 1751 C CB . SER A 1 226 ? 67.628 105.829 19.316 1.00 33.33 ? 226 SER A CB 1 ATOM 1752 O OG . SER A 1 226 ? 67.821 106.671 18.173 1.00 32.12 ? 226 SER A OG 1 ATOM 1753 N N A PHE A 1 227 ? 69.392 107.137 21.655 0.50 33.44 ? 227 PHE A N 1 ATOM 1754 N N B PHE A 1 227 ? 69.383 107.207 21.704 0.50 33.58 ? 227 PHE A N 1 ATOM 1755 C CA A PHE A 1 227 ? 70.499 107.942 22.189 0.50 33.60 ? 227 PHE A CA 1 ATOM 1756 C CA B PHE A 1 227 ? 70.438 108.124 22.171 0.50 33.84 ? 227 PHE A CA 1 ATOM 1757 C C A PHE A 1 227 ? 71.468 108.572 21.189 0.50 34.24 ? 227 PHE A C 1 ATOM 1758 C C B PHE A 1 227 ? 71.163 108.888 21.065 0.50 34.10 ? 227 PHE A C 1 ATOM 1759 O O A PHE A 1 227 ? 72.355 109.323 21.618 0.50 34.12 ? 227 PHE A O 1 ATOM 1760 O O B PHE A 1 227 ? 71.617 110.017 21.301 0.50 33.17 ? 227 PHE A O 1 ATOM 1761 C CB A PHE A 1 227 ? 71.308 107.138 23.246 0.50 33.88 ? 227 PHE A CB 1 ATOM 1762 C CB B PHE A 1 227 ? 71.503 107.376 22.992 0.50 34.60 ? 227 PHE A CB 1 ATOM 1763 C CG A PHE A 1 227 ? 72.058 105.937 22.685 0.50 32.62 ? 227 PHE A CG 1 ATOM 1764 C CG B PHE A 1 227 ? 72.549 106.723 22.136 0.50 35.39 ? 227 PHE A CG 1 ATOM 1765 C CD1 A PHE A 1 227 ? 71.681 104.662 23.028 0.50 31.76 ? 227 PHE A CD1 1 ATOM 1766 C CD1 B PHE A 1 227 ? 72.438 105.383 21.792 0.50 33.39 ? 227 PHE A CD1 1 ATOM 1767 C CD2 A PHE A 1 227 ? 73.150 106.099 21.833 0.50 32.89 ? 227 PHE A CD2 1 ATOM 1768 C CD2 B PHE A 1 227 ? 73.616 107.468 21.633 0.50 34.82 ? 227 PHE A CD2 1 ATOM 1769 C CE1 A PHE A 1 227 ? 72.339 103.562 22.538 0.50 31.33 ? 227 PHE A CE1 1 ATOM 1770 C CE1 B PHE A 1 227 ? 73.376 104.790 20.970 0.50 34.90 ? 227 PHE A CE1 1 ATOM 1771 C CE2 A PHE A 1 227 ? 73.824 105.007 21.335 0.50 33.06 ? 227 PHE A CE2 1 ATOM 1772 C CE2 B PHE A 1 227 ? 74.568 106.880 20.812 0.50 34.74 ? 227 PHE A CE2 1 ATOM 1773 C CZ A PHE A 1 227 ? 73.413 103.722 21.692 0.50 33.19 ? 227 PHE A CZ 1 ATOM 1774 C CZ B PHE A 1 227 ? 74.448 105.534 20.482 0.50 35.31 ? 227 PHE A CZ 1 ATOM 1775 N N . ASN A 1 228 ? 71.320 108.250 19.889 1.00 34.23 ? 228 ASN A N 1 ATOM 1776 C CA . ASN A 1 228 ? 72.164 108.789 18.794 1.00 33.86 ? 228 ASN A CA 1 ATOM 1777 C C . ASN A 1 228 ? 71.480 109.914 18.049 1.00 34.06 ? 228 ASN A C 1 ATOM 1778 O O . ASN A 1 228 ? 72.037 110.495 17.104 1.00 33.85 ? 228 ASN A O 1 ATOM 1779 C CB . ASN A 1 228 ? 72.631 107.679 17.785 1.00 32.84 ? 228 ASN A CB 1 ATOM 1780 C CG . ASN A 1 228 ? 71.452 106.946 17.105 1.00 34.83 ? 228 ASN A CG 1 ATOM 1781 O OD1 . ASN A 1 228 ? 70.471 106.627 17.759 1.00 35.14 ? 228 ASN A OD1 1 ATOM 1782 N ND2 . ASN A 1 228 ? 71.534 106.719 15.784 1.00 35.64 ? 228 ASN A ND2 1 ATOM 1783 N N . ALA A 1 229 ? 70.243 110.193 18.422 1.00 34.48 ? 229 ALA A N 1 ATOM 1784 C CA . ALA A 1 229 ? 69.560 111.378 17.909 1.00 34.71 ? 229 ALA A CA 1 ATOM 1785 C C . ALA A 1 229 ? 70.356 112.632 18.327 1.00 34.61 ? 229 ALA A C 1 ATOM 1786 O O . ALA A 1 229 ? 70.964 112.660 19.416 1.00 34.02 ? 229 ALA A O 1 ATOM 1787 C CB . ALA A 1 229 ? 68.090 111.420 18.429 1.00 34.81 ? 229 ALA A CB 1 ATOM 1788 N N . PRO A 1 230 ? 70.370 113.661 17.487 1.00 34.67 ? 230 PRO A N 1 ATOM 1789 C CA . PRO A 1 230 ? 71.217 114.842 17.740 1.00 35.04 ? 230 PRO A CA 1 ATOM 1790 C C . PRO A 1 230 ? 70.892 115.614 19.031 1.00 35.46 ? 230 PRO A C 1 ATOM 1791 O O . PRO A 1 230 ? 71.775 116.288 19.591 1.00 35.25 ? 230 PRO A O 1 ATOM 1792 C CB . PRO A 1 230 ? 71.017 115.707 16.501 1.00 34.87 ? 230 PRO A CB 1 ATOM 1793 C CG . PRO A 1 230 ? 69.771 115.240 15.869 1.00 35.57 ? 230 PRO A CG 1 ATOM 1794 C CD . PRO A 1 230 ? 69.590 113.789 16.251 1.00 35.38 ? 230 PRO A CD 1 ATOM 1795 N N . TRP A 1 231 ? 69.674 115.458 19.540 1.00 35.69 ? 231 TRP A N 1 ATOM 1796 C CA . TRP A 1 231 ? 69.249 116.148 20.770 1.00 34.79 ? 231 TRP A CA 1 ATOM 1797 C C . TRP A 1 231 ? 69.493 115.350 22.054 1.00 35.57 ? 231 TRP A C 1 ATOM 1798 O O . TRP A 1 231 ? 69.252 115.862 23.136 1.00 34.92 ? 231 TRP A O 1 ATOM 1799 C CB . TRP A 1 231 ? 67.758 116.517 20.680 1.00 34.24 ? 231 TRP A CB 1 ATOM 1800 C CG . TRP A 1 231 ? 66.890 115.364 20.249 1.00 32.93 ? 231 TRP A CG 1 ATOM 1801 C CD1 . TRP A 1 231 ? 66.484 115.083 18.968 1.00 32.77 ? 231 TRP A CD1 1 ATOM 1802 C CD2 . TRP A 1 231 ? 66.391 114.288 21.065 1.00 31.38 ? 231 TRP A CD2 1 ATOM 1803 N NE1 . TRP A 1 231 ? 65.750 113.921 18.943 1.00 30.02 ? 231 TRP A NE1 1 ATOM 1804 C CE2 . TRP A 1 231 ? 65.665 113.420 20.221 1.00 32.71 ? 231 TRP A CE2 1 ATOM 1805 C CE3 . TRP A 1 231 ? 66.456 113.980 22.430 1.00 35.31 ? 231 TRP A CE3 1 ATOM 1806 C CZ2 . TRP A 1 231 ? 65.027 112.260 20.697 1.00 32.93 ? 231 TRP A CZ2 1 ATOM 1807 C CZ3 . TRP A 1 231 ? 65.809 112.788 22.900 1.00 31.48 ? 231 TRP A CZ3 1 ATOM 1808 C CH2 . TRP A 1 231 ? 65.116 111.977 22.039 1.00 30.41 ? 231 TRP A CH2 1 ATOM 1809 N N . ALA A 1 232 ? 69.932 114.094 21.961 1.00 36.42 ? 232 ALA A N 1 ATOM 1810 C CA . ALA A 1 232 ? 69.797 113.177 23.116 1.00 37.39 ? 232 ALA A CA 1 ATOM 1811 C C . ALA A 1 232 ? 70.934 113.147 24.135 1.00 38.79 ? 232 ALA A C 1 ATOM 1812 O O . ALA A 1 232 ? 70.755 112.720 25.284 1.00 39.63 ? 232 ALA A O 1 ATOM 1813 C CB . ALA A 1 232 ? 69.506 111.766 22.624 1.00 37.15 ? 232 ALA A CB 1 ATOM 1814 N N . VAL A 1 233 ? 72.121 113.567 23.735 1.00 40.00 ? 233 VAL A N 1 ATOM 1815 C CA . VAL A 1 233 ? 73.255 113.498 24.657 1.00 41.11 ? 233 VAL A CA 1 ATOM 1816 C C . VAL A 1 233 ? 73.995 114.847 24.641 1.00 43.64 ? 233 VAL A C 1 ATOM 1817 O O . VAL A 1 233 ? 74.318 115.364 23.570 1.00 43.60 ? 233 VAL A O 1 ATOM 1818 C CB . VAL A 1 233 ? 74.232 112.333 24.295 1.00 41.50 ? 233 VAL A CB 1 ATOM 1819 C CG1 . VAL A 1 233 ? 75.428 112.300 25.276 1.00 36.54 ? 233 VAL A CG1 1 ATOM 1820 C CG2 . VAL A 1 233 ? 73.475 110.922 24.214 1.00 37.99 ? 233 VAL A CG2 1 ATOM 1821 N N . THR A 1 234 ? 74.199 115.420 25.825 1.00 45.82 ? 234 THR A N 1 ATOM 1822 C CA . THR A 1 234 ? 74.902 116.703 25.994 1.00 48.56 ? 234 THR A CA 1 ATOM 1823 C C . THR A 1 234 ? 76.398 116.424 26.064 1.00 49.72 ? 234 THR A C 1 ATOM 1824 O O . THR A 1 234 ? 76.826 115.592 26.854 1.00 49.87 ? 234 THR A O 1 ATOM 1825 C CB . THR A 1 234 ? 74.459 117.406 27.326 1.00 48.73 ? 234 THR A CB 1 ATOM 1826 O OG1 . THR A 1 234 ? 73.017 117.474 27.417 1.00 47.59 ? 234 THR A OG1 1 ATOM 1827 C CG2 . THR A 1 234 ? 74.956 118.880 27.364 1.00 48.84 ? 234 THR A CG2 1 ATOM 1828 N N . SER A 1 235 ? 77.195 117.090 25.236 1.00 52.03 ? 235 SER A N 1 ATOM 1829 C CA . SER A 1 235 ? 78.656 116.967 25.370 1.00 55.08 ? 235 SER A CA 1 ATOM 1830 C C . SER A 1 235 ? 79.156 117.503 26.735 1.00 56.31 ? 235 SER A C 1 ATOM 1831 O O . SER A 1 235 ? 78.544 118.394 27.334 1.00 56.77 ? 235 SER A O 1 ATOM 1832 C CB . SER A 1 235 ? 79.364 117.704 24.248 1.00 54.97 ? 235 SER A CB 1 ATOM 1833 O OG . SER A 1 235 ? 79.508 119.065 24.604 1.00 57.66 ? 235 SER A OG 1 ATOM 1834 N N . LEU A 1 236 ? 80.242 116.926 27.230 1.00 58.12 ? 236 LEU A N 1 ATOM 1835 C CA . LEU A 1 236 ? 80.943 117.426 28.415 1.00 60.22 ? 236 LEU A CA 1 ATOM 1836 C C . LEU A 1 236 ? 81.222 118.934 28.288 1.00 60.91 ? 236 LEU A C 1 ATOM 1837 O O . LEU A 1 236 ? 81.030 119.686 29.231 1.00 60.41 ? 236 LEU A O 1 ATOM 1838 C CB . LEU A 1 236 ? 82.250 116.657 28.563 1.00 60.90 ? 236 LEU A CB 1 ATOM 1839 C CG . LEU A 1 236 ? 82.942 116.543 29.910 1.00 63.45 ? 236 LEU A CG 1 ATOM 1840 C CD1 . LEU A 1 236 ? 83.176 115.058 30.255 1.00 64.83 ? 236 LEU A CD1 1 ATOM 1841 C CD2 . LEU A 1 236 ? 84.250 117.353 29.931 1.00 66.39 ? 236 LEU A CD2 1 ATOM 1842 N N . TYR A 1 237 ? 81.639 119.359 27.097 1.00 62.16 ? 237 TYR A N 1 ATOM 1843 C CA . TYR A 1 237 ? 81.849 120.766 26.784 1.00 63.78 ? 237 TYR A CA 1 ATOM 1844 C C . TYR A 1 237 ? 80.584 121.626 27.014 1.00 63.23 ? 237 TYR A C 1 ATOM 1845 O O . TYR A 1 237 ? 80.609 122.535 27.859 1.00 63.49 ? 237 TYR A O 1 ATOM 1846 C CB . TYR A 1 237 ? 82.439 120.928 25.369 1.00 64.91 ? 237 TYR A CB 1 ATOM 1847 C CG . TYR A 1 237 ? 82.695 122.363 24.946 1.00 69.48 ? 237 TYR A CG 1 ATOM 1848 C CD1 . TYR A 1 237 ? 82.084 122.890 23.796 1.00 72.88 ? 237 TYR A CD1 1 ATOM 1849 C CD2 . TYR A 1 237 ? 83.539 123.209 25.704 1.00 73.12 ? 237 TYR A CD2 1 ATOM 1850 C CE1 . TYR A 1 237 ? 82.311 124.222 23.398 1.00 75.10 ? 237 TYR A CE1 1 ATOM 1851 C CE2 . TYR A 1 237 ? 83.769 124.538 25.321 1.00 75.01 ? 237 TYR A CE2 1 ATOM 1852 C CZ . TYR A 1 237 ? 83.146 125.039 24.166 1.00 76.55 ? 237 TYR A CZ 1 ATOM 1853 O OH . TYR A 1 237 ? 83.369 126.350 23.769 1.00 77.98 ? 237 TYR A OH 1 ATOM 1854 N N . GLU A 1 238 ? 79.485 121.318 26.319 1.00 62.01 ? 238 GLU A N 1 ATOM 1855 C CA . GLU A 1 238 ? 78.236 122.051 26.521 1.00 61.39 ? 238 GLU A CA 1 ATOM 1856 C C . GLU A 1 238 ? 77.763 122.004 27.982 1.00 60.11 ? 238 GLU A C 1 ATOM 1857 O O . GLU A 1 238 ? 77.291 122.986 28.501 1.00 59.84 ? 238 GLU A O 1 ATOM 1858 C CB . GLU A 1 238 ? 77.103 121.503 25.653 1.00 61.49 ? 238 GLU A CB 1 ATOM 1859 C CG . GLU A 1 238 ? 77.326 121.475 24.156 1.00 64.90 ? 238 GLU A CG 1 ATOM 1860 C CD . GLU A 1 238 ? 76.478 120.381 23.480 1.00 69.41 ? 238 GLU A CD 1 ATOM 1861 O OE1 . GLU A 1 238 ? 76.337 119.281 24.081 1.00 69.24 ? 238 GLU A OE1 1 ATOM 1862 O OE2 . GLU A 1 238 ? 75.953 120.611 22.349 1.00 69.27 ? 238 GLU A OE2 1 ATOM 1863 N N . ALA A 1 239 ? 77.873 120.853 28.626 1.00 59.49 ? 239 ALA A N 1 ATOM 1864 C CA . ALA A 1 239 ? 77.325 120.667 29.972 1.00 59.24 ? 239 ALA A CA 1 ATOM 1865 C C . ALA A 1 239 ? 77.975 121.594 31.003 1.00 59.56 ? 239 ALA A C 1 ATOM 1866 O O . ALA A 1 239 ? 77.269 122.235 31.783 1.00 59.20 ? 239 ALA A O 1 ATOM 1867 C CB . ALA A 1 239 ? 77.429 119.203 30.404 1.00 58.45 ? 239 ALA A CB 1 ATOM 1868 N N . ARG A 1 240 ? 79.313 121.665 30.993 1.00 60.17 ? 240 ARG A N 1 ATOM 1869 C CA . ARG A 1 240 ? 80.088 122.625 31.824 1.00 60.75 ? 240 ARG A CA 1 ATOM 1870 C C . ARG A 1 240 ? 79.634 124.063 31.596 1.00 59.89 ? 240 ARG A C 1 ATOM 1871 O O . ARG A 1 240 ? 79.320 124.777 32.540 1.00 59.83 ? 240 ARG A O 1 ATOM 1872 C CB . ARG A 1 240 ? 81.608 122.501 31.550 1.00 61.34 ? 240 ARG A CB 1 ATOM 1873 C CG . ARG A 1 240 ? 82.441 123.766 31.921 1.00 65.01 ? 240 ARG A CG 1 ATOM 1874 C CD . ARG A 1 240 ? 83.945 123.525 32.257 1.00 70.40 ? 240 ARG A CD 1 ATOM 1875 N NE . ARG A 1 240 ? 84.303 124.177 33.525 1.00 74.37 ? 240 ARG A NE 1 ATOM 1876 C CZ . ARG A 1 240 ? 84.106 123.631 34.731 1.00 76.43 ? 240 ARG A CZ 1 ATOM 1877 N NH1 . ARG A 1 240 ? 83.590 122.408 34.848 1.00 77.37 ? 240 ARG A NH1 1 ATOM 1878 N NH2 . ARG A 1 240 ? 84.433 124.308 35.828 1.00 78.48 ? 240 ARG A NH2 1 ATOM 1879 N N . ASN A 1 241 ? 79.575 124.458 30.328 1.00 59.63 ? 241 ASN A N 1 ATOM 1880 C CA . ASN A 1 241 ? 79.210 125.802 29.964 1.00 59.72 ? 241 ASN A CA 1 ATOM 1881 C C . ASN A 1 241 ? 77.830 126.154 30.486 1.00 58.78 ? 241 ASN A C 1 ATOM 1882 O O . ASN A 1 241 ? 77.596 127.290 30.947 1.00 58.81 ? 241 ASN A O 1 ATOM 1883 C CB . ASN A 1 241 ? 79.259 125.998 28.442 1.00 60.41 ? 241 ASN A CB 1 ATOM 1884 C CG . ASN A 1 241 ? 79.603 127.451 28.035 1.00 64.27 ? 241 ASN A CG 1 ATOM 1885 O OD1 . ASN A 1 241 ? 80.592 128.038 28.515 1.00 62.21 ? 241 ASN A OD1 1 ATOM 1886 N ND2 . ASN A 1 241 ? 78.785 128.018 27.131 1.00 70.37 ? 241 ASN A ND2 1 ATOM 1887 N N . ARG A 1 242 ? 76.926 125.176 30.398 1.00 56.88 ? 242 ARG A N 1 ATOM 1888 C CA . ARG A 1 242 ? 75.530 125.353 30.771 1.00 55.18 ? 242 ARG A CA 1 ATOM 1889 C C . ARG A 1 242 ? 75.376 125.416 32.296 1.00 54.28 ? 242 ARG A C 1 ATOM 1890 O O . ARG A 1 242 ? 74.656 126.269 32.804 1.00 53.47 ? 242 ARG A O 1 ATOM 1891 C CB . ARG A 1 242 ? 74.660 124.277 30.110 1.00 54.48 ? 242 ARG A CB 1 ATOM 1892 C CG . ARG A 1 242 ? 74.753 124.324 28.583 1.00 55.23 ? 242 ARG A CG 1 ATOM 1893 C CD . ARG A 1 242 ? 73.953 123.251 27.861 1.00 54.99 ? 242 ARG A CD 1 ATOM 1894 N NE . ARG A 1 242 ? 74.148 123.238 26.412 1.00 54.14 ? 242 ARG A NE 1 ATOM 1895 C CZ . ARG A 1 242 ? 73.461 122.454 25.554 1.00 56.13 ? 242 ARG A CZ 1 ATOM 1896 N NH1 . ARG A 1 242 ? 72.518 121.604 25.974 1.00 52.73 ? 242 ARG A NH1 1 ATOM 1897 N NH2 . ARG A 1 242 ? 73.729 122.504 24.259 1.00 53.77 ? 242 ARG A NH2 1 ATOM 1898 N N . THR A 1 243 ? 76.088 124.549 33.009 1.00 53.99 ? 243 THR A N 1 ATOM 1899 C CA . THR A 1 243 ? 76.169 124.618 34.471 1.00 55.12 ? 243 THR A CA 1 ATOM 1900 C C . THR A 1 243 ? 76.716 125.983 34.940 1.00 55.75 ? 243 THR A C 1 ATOM 1901 O O . THR A 1 243 ? 76.242 126.533 35.918 1.00 55.61 ? 243 THR A O 1 ATOM 1902 C CB . THR A 1 243 ? 77.076 123.504 34.999 1.00 54.99 ? 243 THR A CB 1 ATOM 1903 O OG1 . THR A 1 243 ? 76.462 122.233 34.762 1.00 54.27 ? 243 THR A OG1 1 ATOM 1904 C CG2 . THR A 1 243 ? 77.217 123.561 36.535 1.00 55.29 ? 243 THR A CG2 1 ATOM 1905 N N . LEU A 1 244 ? 77.713 126.503 34.224 1.00 56.54 ? 244 LEU A N 1 ATOM 1906 C CA . LEU A 1 244 ? 78.320 127.804 34.534 1.00 57.09 ? 244 LEU A CA 1 ATOM 1907 C C . LEU A 1 244 ? 77.394 128.948 34.219 1.00 56.66 ? 244 LEU A C 1 ATOM 1908 O O . LEU A 1 244 ? 77.299 129.899 34.987 1.00 56.76 ? 244 LEU A O 1 ATOM 1909 C CB . LEU A 1 244 ? 79.636 128.012 33.765 1.00 57.03 ? 244 LEU A CB 1 ATOM 1910 C CG . LEU A 1 244 ? 80.795 127.112 34.141 1.00 57.36 ? 244 LEU A CG 1 ATOM 1911 C CD1 . LEU A 1 244 ? 82.036 127.530 33.369 1.00 59.09 ? 244 LEU A CD1 1 ATOM 1912 C CD2 . LEU A 1 244 ? 80.996 127.152 35.653 1.00 58.84 ? 244 LEU A CD2 1 ATOM 1913 N N . ASN A 1 245 ? 76.717 128.872 33.083 1.00 56.82 ? 245 ASN A N 1 ATOM 1914 C CA . ASN A 1 245 ? 75.699 129.875 32.798 1.00 57.16 ? 245 ASN A CA 1 ATOM 1915 C C . ASN A 1 245 ? 74.566 129.873 33.824 1.00 57.06 ? 245 ASN A C 1 ATOM 1916 O O . ASN A 1 245 ? 74.119 130.938 34.245 1.00 57.41 ? 245 ASN A O 1 ATOM 1917 C CB . ASN A 1 245 ? 75.205 129.767 31.354 1.00 57.44 ? 245 ASN A CB 1 ATOM 1918 C CG . ASN A 1 245 ? 76.332 129.956 30.355 1.00 59.27 ? 245 ASN A CG 1 ATOM 1919 O OD1 . ASN A 1 245 ? 77.442 130.368 30.725 1.00 61.05 ? 245 ASN A OD1 1 ATOM 1920 N ND2 . ASN A 1 245 ? 76.067 129.646 29.092 1.00 59.51 ? 245 ASN A ND2 1 ATOM 1921 N N . LEU A 1 246 ? 74.119 128.690 34.248 1.00 56.78 ? 246 LEU A N 1 ATOM 1922 C CA . LEU A 1 246 ? 73.104 128.616 35.284 1.00 56.69 ? 246 LEU A CA 1 ATOM 1923 C C . LEU A 1 246 ? 73.595 129.311 36.565 1.00 56.87 ? 246 LEU A C 1 ATOM 1924 O O . LEU A 1 246 ? 72.859 130.094 37.138 1.00 55.70 ? 246 LEU A O 1 ATOM 1925 C CB . LEU A 1 246 ? 72.669 127.165 35.580 1.00 56.07 ? 246 LEU A CB 1 ATOM 1926 C CG . LEU A 1 246 ? 71.342 127.071 36.360 1.00 55.41 ? 246 LEU A CG 1 ATOM 1927 C CD1 . LEU A 1 246 ? 70.226 127.827 35.640 1.00 52.01 ? 246 LEU A CD1 1 ATOM 1928 C CD2 . LEU A 1 246 ? 70.919 125.632 36.624 1.00 53.41 ? 246 LEU A CD2 1 ATOM 1929 N N . ALA A 1 247 ? 74.828 129.000 36.986 1.00 57.89 ? 247 ALA A N 1 ATOM 1930 C CA . ALA A 1 247 ? 75.520 129.645 38.122 1.00 59.08 ? 247 ALA A CA 1 ATOM 1931 C C . ALA A 1 247 ? 75.492 131.163 38.016 1.00 59.89 ? 247 ALA A C 1 ATOM 1932 O O . ALA A 1 247 ? 75.022 131.852 38.921 1.00 60.41 ? 247 ALA A O 1 ATOM 1933 C CB . ALA A 1 247 ? 76.950 129.179 38.188 1.00 58.87 ? 247 ALA A CB 1 ATOM 1934 N N . LYS A 1 248 ? 75.981 131.671 36.893 1.00 60.55 ? 248 LYS A N 1 ATOM 1935 C CA . LYS A 1 248 ? 75.987 133.092 36.631 1.00 61.67 ? 248 LYS A CA 1 ATOM 1936 C C . LYS A 1 248 ? 74.585 133.675 36.837 1.00 61.47 ? 248 LYS A C 1 ATOM 1937 O O . LYS A 1 248 ? 74.392 134.548 37.691 1.00 61.69 ? 248 LYS A O 1 ATOM 1938 C CB . LYS A 1 248 ? 76.518 133.387 35.223 1.00 62.14 ? 248 LYS A CB 1 ATOM 1939 C CG . LYS A 1 248 ? 77.111 134.793 35.094 1.00 65.46 ? 248 LYS A CG 1 ATOM 1940 C CD . LYS A 1 248 ? 77.789 135.028 33.738 1.00 68.27 ? 248 LYS A CD 1 ATOM 1941 C CE . LYS A 1 248 ? 78.271 136.497 33.607 1.00 71.71 ? 248 LYS A CE 1 ATOM 1942 N NZ . LYS A 1 248 ? 79.683 136.734 34.078 1.00 71.20 ? 248 LYS A NZ 1 ATOM 1943 N N . LEU A 1 249 ? 73.611 133.143 36.099 1.00 60.81 ? 249 LEU A N 1 ATOM 1944 C CA . LEU A 1 249 ? 72.237 133.655 36.085 1.00 59.56 ? 249 LEU A CA 1 ATOM 1945 C C . LEU A 1 249 ? 71.557 133.645 37.452 1.00 59.45 ? 249 LEU A C 1 ATOM 1946 O O . LEU A 1 249 ? 70.548 134.340 37.656 1.00 59.76 ? 249 LEU A O 1 ATOM 1947 C CB . LEU A 1 249 ? 71.391 132.881 35.067 1.00 59.56 ? 249 LEU A CB 1 ATOM 1948 C CG . LEU A 1 249 ? 71.725 133.018 33.575 1.00 58.83 ? 249 LEU A CG 1 ATOM 1949 C CD1 . LEU A 1 249 ? 71.355 131.775 32.777 1.00 59.06 ? 249 LEU A CD1 1 ATOM 1950 C CD2 . LEU A 1 249 ? 71.023 134.206 33.002 1.00 60.80 ? 249 LEU A CD2 1 ATOM 1951 N N . THR A 1 250 ? 72.101 132.883 38.390 1.00 58.59 ? 250 THR A N 1 ATOM 1952 C CA . THR A 1 250 ? 71.482 132.767 39.708 1.00 58.97 ? 250 THR A CA 1 ATOM 1953 C C . THR A 1 250 ? 72.310 133.381 40.849 1.00 59.77 ? 250 THR A C 1 ATOM 1954 O O . THR A 1 250 ? 71.976 133.203 42.029 1.00 59.98 ? 250 THR A O 1 ATOM 1955 C CB . THR A 1 250 ? 71.219 131.289 40.054 1.00 58.40 ? 250 THR A CB 1 ATOM 1956 O OG1 . THR A 1 250 ? 72.431 130.542 39.873 1.00 57.06 ? 250 THR A OG1 1 ATOM 1957 C CG2 . THR A 1 250 ? 70.173 130.658 39.126 1.00 56.93 ? 250 THR A CG2 1 ATOM 1958 N N . GLY A 1 251 ? 73.393 134.068 40.502 1.00 60.53 ? 251 GLY A N 1 ATOM 1959 C CA . GLY A 1 251 ? 74.293 134.659 41.496 1.00 61.42 ? 251 GLY A CA 1 ATOM 1960 C C . GLY A 1 251 ? 75.150 133.629 42.194 1.00 62.33 ? 251 GLY A C 1 ATOM 1961 O O . GLY A 1 251 ? 75.662 133.867 43.300 1.00 62.10 ? 251 GLY A O 1 ATOM 1962 N N . CYS A 1 252 ? 75.324 132.489 41.528 1.00 62.98 ? 252 CYS A N 1 ATOM 1963 C CA . CYS A 1 252 ? 75.998 131.346 42.102 1.00 63.83 ? 252 CYS A CA 1 ATOM 1964 C C . CYS A 1 252 ? 77.377 131.106 41.503 1.00 64.98 ? 252 CYS A C 1 ATOM 1965 O O . CYS A 1 252 ? 78.026 130.092 41.818 1.00 64.69 ? 252 CYS A O 1 ATOM 1966 C CB . CYS A 1 252 ? 75.130 130.091 41.954 1.00 63.70 ? 252 CYS A CB 1 ATOM 1967 S SG . CYS A 1 252 ? 73.751 129.983 43.104 1.00 62.50 ? 252 CYS A SG 1 ATOM 1968 N N . SER A 1 253 ? 77.839 132.019 40.645 1.00 66.57 ? 253 SER A N 1 ATOM 1969 C CA . SER A 1 253 ? 79.228 131.932 40.164 1.00 68.13 ? 253 SER A CA 1 ATOM 1970 C C . SER A 1 253 ? 80.187 131.930 41.365 1.00 69.24 ? 253 SER A C 1 ATOM 1971 O O . SER A 1 253 ? 80.098 132.791 42.234 1.00 69.30 ? 253 SER A O 1 ATOM 1972 C CB . SER A 1 253 ? 79.554 133.069 39.207 1.00 68.03 ? 253 SER A CB 1 ATOM 1973 O OG . SER A 1 253 ? 78.843 132.920 38.000 1.00 68.64 ? 253 SER A OG 1 ATOM 1974 N N . ARG A 1 254 ? 81.062 130.930 41.424 1.00 70.73 ? 254 ARG A N 1 ATOM 1975 C CA . ARG A 1 254 ? 82.005 130.752 42.540 1.00 71.90 ? 254 ARG A CA 1 ATOM 1976 C C . ARG A 1 254 ? 83.365 130.270 42.028 1.00 73.30 ? 254 ARG A C 1 ATOM 1977 O O . ARG A 1 254 ? 83.634 130.346 40.830 1.00 73.75 ? 254 ARG A O 1 ATOM 1978 C CB . ARG A 1 254 ? 81.441 129.773 43.582 1.00 71.42 ? 254 ARG A CB 1 ATOM 1979 C CG . ARG A 1 254 ? 81.116 130.382 44.947 1.00 69.89 ? 254 ARG A CG 1 ATOM 1980 C CD . ARG A 1 254 ? 80.240 131.600 44.886 1.00 66.23 ? 254 ARG A CD 1 ATOM 1981 N NE . ARG A 1 254 ? 79.269 131.646 45.973 1.00 63.53 ? 254 ARG A NE 1 ATOM 1982 C CZ . ARG A 1 254 ? 78.114 132.290 45.896 1.00 61.28 ? 254 ARG A CZ 1 ATOM 1983 N NH1 . ARG A 1 254 ? 77.284 132.281 46.924 1.00 59.39 ? 254 ARG A NH1 1 ATOM 1984 N NH2 . ARG A 1 254 ? 77.781 132.928 44.780 1.00 60.06 ? 254 ARG A NH2 1 ATOM 1985 N N . GLU A 1 255 ? 84.215 129.774 42.926 1.00 74.44 ? 255 GLU A N 1 ATOM 1986 C CA . GLU A 1 255 ? 85.503 129.212 42.528 1.00 75.70 ? 255 GLU A CA 1 ATOM 1987 C C . GLU A 1 255 ? 85.602 127.711 42.853 1.00 75.82 ? 255 GLU A C 1 ATOM 1988 O O . GLU A 1 255 ? 85.919 126.897 41.974 1.00 76.07 ? 255 GLU A O 1 ATOM 1989 C CB . GLU A 1 255 ? 86.673 130.029 43.110 1.00 76.47 ? 255 GLU A CB 1 ATOM 1990 C CG . GLU A 1 255 ? 86.691 130.197 44.641 1.00 78.86 ? 255 GLU A CG 1 ATOM 1991 C CD . GLU A 1 255 ? 85.376 130.713 45.214 1.00 81.08 ? 255 GLU A CD 1 ATOM 1992 O OE1 . GLU A 1 255 ? 84.940 131.840 44.847 1.00 82.27 ? 255 GLU A OE1 1 ATOM 1993 O OE2 . GLU A 1 255 ? 84.776 129.981 46.030 1.00 81.90 ? 255 GLU A OE2 1 ATOM 1994 N N . ASN A 1 256 ? 85.339 127.350 44.108 1.00 75.58 ? 256 ASN A N 1 ATOM 1995 C CA . ASN A 1 256 ? 85.117 125.964 44.471 1.00 75.35 ? 256 ASN A CA 1 ATOM 1996 C C . ASN A 1 256 ? 83.863 125.574 43.679 1.00 74.98 ? 256 ASN A C 1 ATOM 1997 O O . ASN A 1 256 ? 82.833 126.272 43.743 1.00 75.04 ? 256 ASN A O 1 ATOM 1998 C CB . ASN A 1 256 ? 84.916 125.840 45.997 1.00 75.50 ? 256 ASN A CB 1 ATOM 1999 C CG . ASN A 1 256 ? 85.037 124.394 46.529 1.00 76.38 ? 256 ASN A CG 1 ATOM 2000 O OD1 . ASN A 1 256 ? 84.368 123.472 46.058 1.00 78.14 ? 256 ASN A OD1 1 ATOM 2001 N ND2 . ASN A 1 256 ? 85.863 124.216 47.553 1.00 76.31 ? 256 ASN A ND2 1 ATOM 2002 N N . GLU A 1 257 ? 83.977 124.511 42.881 1.00 74.02 ? 257 GLU A N 1 ATOM 2003 C CA . GLU A 1 257 ? 82.838 123.986 42.128 1.00 72.83 ? 257 GLU A CA 1 ATOM 2004 C C . GLU A 1 257 ? 81.778 123.439 43.054 1.00 72.34 ? 257 GLU A C 1 ATOM 2005 O O . GLU A 1 257 ? 80.592 123.512 42.747 1.00 72.11 ? 257 GLU A O 1 ATOM 2006 C CB . GLU A 1 257 ? 83.268 122.889 41.164 1.00 73.13 ? 257 GLU A CB 1 ATOM 2007 C CG . GLU A 1 257 ? 83.773 123.405 39.828 1.00 72.13 ? 257 GLU A CG 1 ATOM 2008 C CD . GLU A 1 257 ? 84.033 122.285 38.831 1.00 72.66 ? 257 GLU A CD 1 ATOM 2009 O OE1 . GLU A 1 257 ? 83.938 121.073 39.205 1.00 71.49 ? 257 GLU A OE1 1 ATOM 2010 O OE2 . GLU A 1 257 ? 84.321 122.635 37.664 1.00 70.83 ? 257 GLU A OE2 1 ATOM 2011 N N . THR A 1 258 ? 82.203 122.885 44.189 1.00 71.48 ? 258 THR A N 1 ATOM 2012 C CA . THR A 1 258 ? 81.251 122.387 45.177 1.00 70.67 ? 258 THR A CA 1 ATOM 2013 C C . THR A 1 258 ? 80.545 123.549 45.900 1.00 69.57 ? 258 THR A C 1 ATOM 2014 O O . THR A 1 258 ? 79.460 123.370 46.460 1.00 69.37 ? 258 THR A O 1 ATOM 2015 C CB . THR A 1 258 ? 81.917 121.373 46.144 1.00 70.94 ? 258 THR A CB 1 ATOM 2016 O OG1 . THR A 1 258 ? 82.526 120.319 45.383 1.00 70.81 ? 258 THR A OG1 1 ATOM 2017 C CG2 . THR A 1 258 ? 80.855 120.618 46.968 1.00 71.85 ? 258 THR A CG2 1 ATOM 2018 N N . GLU A 1 259 ? 81.153 124.740 45.842 1.00 68.22 ? 259 GLU A N 1 ATOM 2019 C CA . GLU A 1 259 ? 80.495 125.972 46.288 1.00 66.65 ? 259 GLU A CA 1 ATOM 2020 C C . GLU A 1 259 ? 79.423 126.465 45.306 1.00 64.55 ? 259 GLU A C 1 ATOM 2021 O O . GLU A 1 259 ? 78.460 127.093 45.719 1.00 64.46 ? 259 GLU A O 1 ATOM 2022 C CB . GLU A 1 259 ? 81.509 127.093 46.557 1.00 67.08 ? 259 GLU A CB 1 ATOM 2023 C CG . GLU A 1 259 ? 82.173 127.055 47.936 1.00 69.58 ? 259 GLU A CG 1 ATOM 2024 C CD . GLU A 1 259 ? 82.938 128.342 48.261 1.00 72.28 ? 259 GLU A CD 1 ATOM 2025 O OE1 . GLU A 1 259 ? 84.166 128.273 48.522 1.00 72.37 ? 259 GLU A OE1 1 ATOM 2026 O OE2 . GLU A 1 259 ? 82.313 129.437 48.250 1.00 73.58 ? 259 GLU A OE2 1 ATOM 2027 N N . ILE A 1 260 ? 79.596 126.214 44.014 1.00 62.44 ? 260 ILE A N 1 ATOM 2028 C CA . ILE A 1 260 ? 78.517 126.485 43.058 1.00 60.89 ? 260 ILE A CA 1 ATOM 2029 C C . ILE A 1 260 ? 77.300 125.631 43.381 1.00 59.07 ? 260 ILE A C 1 ATOM 2030 O O . ILE A 1 260 ? 76.205 126.158 43.511 1.00 58.45 ? 260 ILE A O 1 ATOM 2031 C CB . ILE A 1 260 ? 78.948 126.263 41.593 1.00 60.91 ? 260 ILE A CB 1 ATOM 2032 C CG1 . ILE A 1 260 ? 80.152 127.140 41.260 1.00 61.49 ? 260 ILE A CG1 1 ATOM 2033 C CG2 . ILE A 1 260 ? 77.769 126.567 40.641 1.00 60.85 ? 260 ILE A CG2 1 ATOM 2034 C CD1 . ILE A 1 260 ? 81.014 126.579 40.139 1.00 62.30 ? 260 ILE A CD1 1 ATOM 2035 N N . ILE A 1 261 ? 77.506 124.327 43.543 1.00 57.42 ? 261 ILE A N 1 ATOM 2036 C CA . ILE A 1 261 ? 76.399 123.426 43.832 1.00 56.85 ? 261 ILE A CA 1 ATOM 2037 C C . ILE A 1 261 ? 75.702 123.761 45.137 1.00 56.83 ? 261 ILE A C 1 ATOM 2038 O O . ILE A 1 261 ? 74.475 123.863 45.139 1.00 56.65 ? 261 ILE A O 1 ATOM 2039 C CB . ILE A 1 261 ? 76.817 121.927 43.762 1.00 56.49 ? 261 ILE A CB 1 ATOM 2040 C CG1 . ILE A 1 261 ? 77.495 121.628 42.416 1.00 56.76 ? 261 ILE A CG1 1 ATOM 2041 C CG2 . ILE A 1 261 ? 75.611 121.012 43.942 1.00 55.12 ? 261 ILE A CG2 1 ATOM 2042 C CD1 . ILE A 1 261 ? 76.663 122.099 41.154 1.00 59.18 ? 261 ILE A CD1 1 ATOM 2043 N N . LYS A 1 262 ? 76.473 123.923 46.226 1.00 57.34 ? 262 LYS A N 1 ATOM 2044 C CA . LYS A 1 262 ? 75.925 124.360 47.526 1.00 57.87 ? 262 LYS A CA 1 ATOM 2045 C C . LYS A 1 262 ? 75.084 125.623 47.354 1.00 57.25 ? 262 LYS A C 1 ATOM 2046 O O . LYS A 1 262 ? 73.939 125.654 47.805 1.00 57.52 ? 262 LYS A O 1 ATOM 2047 C CB . LYS A 1 262 ? 76.998 124.544 48.621 1.00 58.11 ? 262 LYS A CB 1 ATOM 2048 C CG . LYS A 1 262 ? 76.382 124.889 50.020 1.00 60.73 ? 262 LYS A CG 1 ATOM 2049 C CD . LYS A 1 262 ? 77.400 124.926 51.206 1.00 64.19 ? 262 LYS A CD 1 ATOM 2050 C CE . LYS A 1 262 ? 77.453 123.582 52.026 1.00 67.79 ? 262 LYS A CE 1 ATOM 2051 N NZ . LYS A 1 262 ? 76.421 123.466 53.147 1.00 69.94 ? 262 LYS A NZ 1 ATOM 2052 N N . CYS A 1 263 ? 75.618 126.635 46.666 1.00 56.55 ? 263 CYS A N 1 ATOM 2053 C CA . CYS A 1 263 ? 74.819 127.815 46.394 1.00 56.74 ? 263 CYS A CA 1 ATOM 2054 C C . CYS A 1 263 ? 73.523 127.434 45.655 1.00 56.34 ? 263 CYS A C 1 ATOM 2055 O O . CYS A 1 263 ? 72.435 127.762 46.138 1.00 55.99 ? 263 CYS A O 1 ATOM 2056 C CB . CYS A 1 263 ? 75.589 128.881 45.625 1.00 57.10 ? 263 CYS A CB 1 ATOM 2057 S SG . CYS A 1 263 ? 74.515 130.224 45.031 1.00 60.37 ? 263 CYS A SG 1 ATOM 2058 N N . LEU A 1 264 ? 73.641 126.734 44.507 1.00 55.20 ? 264 LEU A N 1 ATOM 2059 C CA . LEU A 1 264 ? 72.461 126.288 43.706 1.00 53.75 ? 264 LEU A CA 1 ATOM 2060 C C . LEU A 1 264 ? 71.400 125.528 44.526 1.00 53.06 ? 264 LEU A C 1 ATOM 2061 O O . LEU A 1 264 ? 70.211 125.642 44.279 1.00 52.01 ? 264 LEU A O 1 ATOM 2062 C CB . LEU A 1 264 ? 72.878 125.499 42.443 1.00 53.28 ? 264 LEU A CB 1 ATOM 2063 C CG . LEU A 1 264 ? 73.442 126.286 41.240 1.00 52.97 ? 264 LEU A CG 1 ATOM 2064 C CD1 . LEU A 1 264 ? 74.019 125.338 40.218 1.00 50.35 ? 264 LEU A CD1 1 ATOM 2065 C CD2 . LEU A 1 264 ? 72.428 127.230 40.541 1.00 52.16 ? 264 LEU A CD2 1 ATOM 2066 N N . ARG A 1 265 ? 71.845 124.776 45.521 1.00 53.34 ? 265 ARG A N 1 ATOM 2067 C CA . ARG A 1 265 ? 70.946 124.077 46.410 1.00 53.58 ? 265 ARG A CA 1 ATOM 2068 C C . ARG A 1 265 ? 70.121 124.983 47.315 1.00 54.72 ? 265 ARG A C 1 ATOM 2069 O O . ARG A 1 265 ? 69.175 124.520 47.971 1.00 54.66 ? 265 ARG A O 1 ATOM 2070 C CB . ARG A 1 265 ? 71.733 123.068 47.240 1.00 53.86 ? 265 ARG A CB 1 ATOM 2071 C CG . ARG A 1 265 ? 72.127 121.815 46.448 1.00 54.52 ? 265 ARG A CG 1 ATOM 2072 C CD . ARG A 1 265 ? 72.282 120.581 47.300 1.00 57.96 ? 265 ARG A CD 1 ATOM 2073 N NE . ARG A 1 265 ? 73.672 120.154 47.343 1.00 64.27 ? 265 ARG A NE 1 ATOM 2074 C CZ . ARG A 1 265 ? 74.555 120.469 48.293 1.00 66.02 ? 265 ARG A CZ 1 ATOM 2075 N NH1 . ARG A 1 265 ? 75.788 120.014 48.187 1.00 64.21 ? 265 ARG A NH1 1 ATOM 2076 N NH2 . ARG A 1 265 ? 74.219 121.221 49.345 1.00 68.19 ? 265 ARG A NH2 1 ATOM 2077 N N . ASN A 1 266 ? 70.478 126.264 47.374 1.00 55.81 ? 266 ASN A N 1 ATOM 2078 C CA . ASN A 1 266 ? 69.721 127.218 48.183 1.00 57.59 ? 266 ASN A CA 1 ATOM 2079 C C . ASN A 1 266 ? 68.710 127.977 47.395 1.00 57.46 ? 266 ASN A C 1 ATOM 2080 O O . ASN A 1 266 ? 67.819 128.584 47.969 1.00 57.84 ? 266 ASN A O 1 ATOM 2081 C CB . ASN A 1 266 ? 70.639 128.192 48.931 1.00 58.58 ? 266 ASN A CB 1 ATOM 2082 C CG . ASN A 1 266 ? 71.327 127.543 50.094 1.00 60.91 ? 266 ASN A CG 1 ATOM 2083 O OD1 . ASN A 1 266 ? 70.763 126.662 50.754 1.00 64.43 ? 266 ASN A OD1 1 ATOM 2084 N ND2 . ASN A 1 266 ? 72.566 127.956 50.349 1.00 65.93 ? 266 ASN A ND2 1 ATOM 2085 N N . LYS A 1 267 ? 68.833 127.926 46.072 1.00 57.90 ? 267 LYS A N 1 ATOM 2086 C CA . LYS A 1 267 ? 67.864 128.577 45.195 1.00 57.76 ? 267 LYS A CA 1 ATOM 2087 C C . LYS A 1 267 ? 66.506 127.900 45.265 1.00 57.89 ? 267 LYS A C 1 ATOM 2088 O O . LYS A 1 267 ? 66.410 126.718 45.577 1.00 57.21 ? 267 LYS A O 1 ATOM 2089 C CB . LYS A 1 267 ? 68.412 128.683 43.769 1.00 58.02 ? 267 LYS A CB 1 ATOM 2090 C CG . LYS A 1 267 ? 69.628 129.637 43.654 1.00 59.04 ? 267 LYS A CG 1 ATOM 2091 C CD . LYS A 1 267 ? 69.223 131.101 43.939 1.00 62.13 ? 267 LYS A CD 1 ATOM 2092 C CE . LYS A 1 267 ? 70.345 131.954 44.552 1.00 67.20 ? 267 LYS A CE 1 ATOM 2093 N NZ . LYS A 1 267 ? 69.845 133.346 44.909 1.00 69.34 ? 267 LYS A NZ 1 ATOM 2094 N N . ASP A 1 268 ? 65.442 128.680 45.066 1.00 58.71 ? 268 ASP A N 1 ATOM 2095 C CA . ASP A 1 268 ? 64.099 128.121 44.981 1.00 59.04 ? 268 ASP A CA 1 ATOM 2096 C C . ASP A 1 268 ? 63.997 127.344 43.659 1.00 57.87 ? 268 ASP A C 1 ATOM 2097 O O . ASP A 1 268 ? 64.408 127.855 42.615 1.00 57.63 ? 268 ASP A O 1 ATOM 2098 C CB . ASP A 1 268 ? 63.026 129.220 45.011 1.00 59.82 ? 268 ASP A CB 1 ATOM 2099 C CG . ASP A 1 268 ? 62.758 129.752 46.421 1.00 63.85 ? 268 ASP A CG 1 ATOM 2100 O OD1 . ASP A 1 268 ? 62.355 130.943 46.541 1.00 67.81 ? 268 ASP A OD1 1 ATOM 2101 O OD2 . ASP A 1 268 ? 62.926 129.070 47.461 1.00 67.09 ? 268 ASP A OD2 1 ATOM 2102 N N . PRO A 1 269 ? 63.423 126.144 43.703 1.00 56.90 ? 269 PRO A N 1 ATOM 2103 C CA . PRO A 1 269 ? 63.223 125.314 42.498 1.00 56.55 ? 269 PRO A CA 1 ATOM 2104 C C . PRO A 1 269 ? 62.791 126.172 41.315 1.00 55.88 ? 269 PRO A C 1 ATOM 2105 O O . PRO A 1 269 ? 63.279 126.019 40.198 1.00 55.53 ? 269 PRO A O 1 ATOM 2106 C CB . PRO A 1 269 ? 62.069 124.400 42.905 1.00 56.93 ? 269 PRO A CB 1 ATOM 2107 C CG . PRO A 1 269 ? 62.122 124.335 44.432 1.00 56.97 ? 269 PRO A CG 1 ATOM 2108 C CD . PRO A 1 269 ? 62.905 125.505 44.923 1.00 56.64 ? 269 PRO A CD 1 ATOM 2109 N N . GLN A 1 270 ? 61.907 127.120 41.599 1.00 55.79 ? 270 GLN A N 1 ATOM 2110 C CA . GLN A 1 270 ? 61.335 127.995 40.593 1.00 55.40 ? 270 GLN A CA 1 ATOM 2111 C C . GLN A 1 270 ? 62.381 128.944 39.993 1.00 54.19 ? 270 GLN A C 1 ATOM 2112 O O . GLN A 1 270 ? 62.289 129.325 38.838 1.00 54.01 ? 270 GLN A O 1 ATOM 2113 C CB . GLN A 1 270 ? 60.135 128.739 41.211 1.00 55.89 ? 270 GLN A CB 1 ATOM 2114 C CG . GLN A 1 270 ? 59.159 129.321 40.216 1.00 59.20 ? 270 GLN A CG 1 ATOM 2115 C CD . GLN A 1 270 ? 58.672 128.299 39.190 1.00 63.46 ? 270 GLN A CD 1 ATOM 2116 O OE1 . GLN A 1 270 ? 58.088 127.264 39.558 1.00 62.74 ? 270 GLN A OE1 1 ATOM 2117 N NE2 . GLN A 1 270 ? 58.926 128.581 37.900 1.00 63.40 ? 270 GLN A NE2 1 ATOM 2118 N N . GLU A 1 271 ? 63.409 129.299 40.755 1.00 53.90 ? 271 GLU A N 1 ATOM 2119 C CA . GLU A 1 271 ? 64.472 130.147 40.182 1.00 53.65 ? 271 GLU A CA 1 ATOM 2120 C C . GLU A 1 271 ? 65.389 129.332 39.278 1.00 52.59 ? 271 GLU A C 1 ATOM 2121 O O . GLU A 1 271 ? 65.906 129.839 38.268 1.00 52.27 ? 271 GLU A O 1 ATOM 2122 C CB . GLU A 1 271 ? 65.295 130.882 41.265 1.00 54.28 ? 271 GLU A CB 1 ATOM 2123 C CG . GLU A 1 271 ? 66.502 131.635 40.695 1.00 56.55 ? 271 GLU A CG 1 ATOM 2124 C CD . GLU A 1 271 ? 67.054 132.763 41.593 1.00 61.56 ? 271 GLU A CD 1 ATOM 2125 O OE1 . GLU A 1 271 ? 66.820 132.749 42.844 1.00 61.38 ? 271 GLU A OE1 1 ATOM 2126 O OE2 . GLU A 1 271 ? 67.749 133.662 41.035 1.00 61.40 ? 271 GLU A OE2 1 ATOM 2127 N N . ILE A 1 272 ? 65.609 128.073 39.640 1.00 51.34 ? 272 ILE A N 1 ATOM 2128 C CA . ILE A 1 272 ? 66.351 127.186 38.752 1.00 50.73 ? 272 ILE A CA 1 ATOM 2129 C C . ILE A 1 272 ? 65.629 127.043 37.401 1.00 50.18 ? 272 ILE A C 1 ATOM 2130 O O . ILE A 1 272 ? 66.258 127.251 36.352 1.00 50.23 ? 272 ILE A O 1 ATOM 2131 C CB . ILE A 1 272 ? 66.644 125.861 39.451 1.00 51.13 ? 272 ILE A CB 1 ATOM 2132 C CG1 . ILE A 1 272 ? 67.772 126.086 40.469 1.00 51.42 ? 272 ILE A CG1 1 ATOM 2133 C CG2 . ILE A 1 272 ? 67.049 124.764 38.436 1.00 51.42 ? 272 ILE A CG2 1 ATOM 2134 C CD1 . ILE A 1 272 ? 67.826 125.073 41.591 1.00 53.12 ? 272 ILE A CD1 1 ATOM 2135 N N . LEU A 1 273 ? 64.313 126.787 37.434 1.00 49.68 ? 273 LEU A N 1 ATOM 2136 C CA . LEU A 1 273 ? 63.507 126.568 36.219 1.00 49.59 ? 273 LEU A CA 1 ATOM 2137 C C . LEU A 1 273 ? 63.504 127.762 35.273 1.00 51.01 ? 273 LEU A C 1 ATOM 2138 O O . LEU A 1 273 ? 63.754 127.617 34.052 1.00 50.18 ? 273 LEU A O 1 ATOM 2139 C CB . LEU A 1 273 ? 62.060 126.219 36.562 1.00 49.12 ? 273 LEU A CB 1 ATOM 2140 C CG . LEU A 1 273 ? 61.781 124.862 37.209 1.00 49.08 ? 273 LEU A CG 1 ATOM 2141 C CD1 . LEU A 1 273 ? 60.295 124.700 37.570 1.00 48.47 ? 273 LEU A CD1 1 ATOM 2142 C CD2 . LEU A 1 273 ? 62.240 123.731 36.271 1.00 46.96 ? 273 LEU A CD2 1 ATOM 2143 N N . LEU A 1 274 ? 63.230 128.942 35.850 1.00 51.72 ? 274 LEU A N 1 ATOM 2144 C CA . LEU A 1 274 ? 63.226 130.199 35.113 1.00 52.76 ? 274 LEU A CA 1 ATOM 2145 C C . LEU A 1 274 ? 64.537 130.415 34.335 1.00 52.39 ? 274 LEU A C 1 ATOM 2146 O O . LEU A 1 274 ? 64.537 130.870 33.192 1.00 52.20 ? 274 LEU A O 1 ATOM 2147 C CB . LEU A 1 274 ? 62.970 131.348 36.095 1.00 53.34 ? 274 LEU A CB 1 ATOM 2148 C CG . LEU A 1 274 ? 62.842 132.782 35.595 1.00 57.11 ? 274 LEU A CG 1 ATOM 2149 C CD1 . LEU A 1 274 ? 61.366 133.133 35.194 1.00 59.68 ? 274 LEU A CD1 1 ATOM 2150 C CD2 . LEU A 1 274 ? 63.366 133.767 36.676 1.00 58.87 ? 274 LEU A CD2 1 ATOM 2151 N N . ASN A 1 275 ? 65.661 130.062 34.939 1.00 52.89 ? 275 ASN A N 1 ATOM 2152 C CA . ASN A 1 275 ? 66.940 130.262 34.260 1.00 53.67 ? 275 ASN A CA 1 ATOM 2153 C C . ASN A 1 275 ? 67.449 129.199 33.245 1.00 53.98 ? 275 ASN A C 1 ATOM 2154 O O . ASN A 1 275 ? 68.416 129.459 32.508 1.00 54.29 ? 275 ASN A O 1 ATOM 2155 C CB . ASN A 1 275 ? 67.988 130.667 35.297 1.00 54.00 ? 275 ASN A CB 1 ATOM 2156 C CG . ASN A 1 275 ? 67.693 132.057 35.876 1.00 54.57 ? 275 ASN A CG 1 ATOM 2157 O OD1 . ASN A 1 275 ? 67.467 132.213 37.081 1.00 58.02 ? 275 ASN A OD1 1 ATOM 2158 N ND2 . ASN A 1 275 ? 67.627 133.052 34.999 1.00 52.15 ? 275 ASN A ND2 1 ATOM 2159 N N . GLU A 1 276 ? 66.784 128.037 33.190 1.00 54.04 ? 276 GLU A N 1 ATOM 2160 C CA . GLU A 1 276 ? 67.196 126.915 32.327 1.00 54.00 ? 276 GLU A CA 1 ATOM 2161 C C . GLU A 1 276 ? 67.224 127.287 30.861 1.00 55.19 ? 276 GLU A C 1 ATOM 2162 O O . GLU A 1 276 ? 68.155 126.904 30.149 1.00 55.30 ? 276 GLU A O 1 ATOM 2163 C CB . GLU A 1 276 ? 66.268 125.705 32.511 1.00 53.75 ? 276 GLU A CB 1 ATOM 2164 C CG . GLU A 1 276 ? 66.399 125.004 33.853 1.00 53.00 ? 276 GLU A CG 1 ATOM 2165 C CD . GLU A 1 276 ? 65.588 123.721 33.941 1.00 51.47 ? 276 GLU A CD 1 ATOM 2166 O OE1 . GLU A 1 276 ? 64.792 123.423 33.045 1.00 50.97 ? 276 GLU A OE1 1 ATOM 2167 O OE2 . GLU A 1 276 ? 65.737 123.006 34.929 1.00 54.27 ? 276 GLU A OE2 1 ATOM 2168 N N . ALA A 1 277 ? 66.218 128.044 30.408 1.00 56.50 ? 277 ALA A N 1 ATOM 2169 C CA . ALA A 1 277 ? 66.068 128.352 28.983 1.00 57.65 ? 277 ALA A CA 1 ATOM 2170 C C . ALA A 1 277 ? 67.272 129.096 28.412 1.00 58.96 ? 277 ALA A C 1 ATOM 2171 O O . ALA A 1 277 ? 67.679 128.894 27.247 1.00 59.23 ? 277 ALA A O 1 ATOM 2172 C CB . ALA A 1 277 ? 64.815 129.121 28.759 1.00 58.14 ? 277 ALA A CB 1 ATOM 2173 N N . PHE A 1 278 ? 67.879 129.913 29.267 1.00 60.02 ? 278 PHE A N 1 ATOM 2174 C CA . PHE A 1 278 ? 68.863 130.894 28.828 1.00 60.51 ? 278 PHE A CA 1 ATOM 2175 C C . PHE A 1 278 ? 70.282 130.402 28.888 1.00 60.63 ? 278 PHE A C 1 ATOM 2176 O O . PHE A 1 278 ? 71.183 131.104 28.429 1.00 61.23 ? 278 PHE A O 1 ATOM 2177 C CB . PHE A 1 278 ? 68.725 132.165 29.659 1.00 61.09 ? 278 PHE A CB 1 ATOM 2178 C CG . PHE A 1 278 ? 67.325 132.643 29.758 1.00 62.53 ? 278 PHE A CG 1 ATOM 2179 C CD1 . PHE A 1 278 ? 66.624 132.520 30.943 1.00 65.51 ? 278 PHE A CD1 1 ATOM 2180 C CD2 . PHE A 1 278 ? 66.683 133.176 28.642 1.00 65.55 ? 278 PHE A CD2 1 ATOM 2181 C CE1 . PHE A 1 278 ? 65.308 132.941 31.030 1.00 66.74 ? 278 PHE A CE1 1 ATOM 2182 C CE2 . PHE A 1 278 ? 65.361 133.603 28.715 1.00 66.93 ? 278 PHE A CE2 1 ATOM 2183 C CZ . PHE A 1 278 ? 64.674 133.486 29.905 1.00 67.53 ? 278 PHE A CZ 1 ATOM 2184 N N . VAL A 1 279 ? 70.497 129.201 29.422 1.00 60.16 ? 279 VAL A N 1 ATOM 2185 C CA . VAL A 1 279 ? 71.865 128.707 29.569 1.00 60.26 ? 279 VAL A CA 1 ATOM 2186 C C . VAL A 1 279 ? 72.602 128.511 28.228 1.00 60.73 ? 279 VAL A C 1 ATOM 2187 O O . VAL A 1 279 ? 73.821 128.379 28.219 1.00 60.57 ? 279 VAL A O 1 ATOM 2188 C CB . VAL A 1 279 ? 71.971 127.466 30.496 1.00 60.47 ? 279 VAL A CB 1 ATOM 2189 C CG1 . VAL A 1 279 ? 71.337 127.758 31.858 1.00 58.44 ? 279 VAL A CG1 1 ATOM 2190 C CG2 . VAL A 1 279 ? 71.353 126.216 29.846 1.00 59.57 ? 279 VAL A CG2 1 ATOM 2191 N N . VAL A 1 280 ? 71.853 128.523 27.119 1.00 61.72 ? 280 VAL A N 1 ATOM 2192 C CA . VAL A 1 280 ? 72.395 128.506 25.749 1.00 62.72 ? 280 VAL A CA 1 ATOM 2193 C C . VAL A 1 280 ? 72.084 129.827 25.038 1.00 63.85 ? 280 VAL A C 1 ATOM 2194 O O . VAL A 1 280 ? 70.983 130.389 25.208 1.00 64.36 ? 280 VAL A O 1 ATOM 2195 C CB . VAL A 1 280 ? 71.846 127.306 24.858 1.00 63.19 ? 280 VAL A CB 1 ATOM 2196 C CG1 . VAL A 1 280 ? 72.483 125.969 25.240 1.00 62.47 ? 280 VAL A CG1 1 ATOM 2197 C CG2 . VAL A 1 280 ? 70.319 127.217 24.879 1.00 62.89 ? 280 VAL A CG2 1 ATOM 2198 N N . PRO A 1 281 ? 73.035 130.338 24.248 1.00 64.29 ? 281 PRO A N 1 ATOM 2199 C CA . PRO A 1 281 ? 72.836 131.611 23.544 1.00 64.61 ? 281 PRO A CA 1 ATOM 2200 C C . PRO A 1 281 ? 71.703 131.537 22.519 1.00 64.25 ? 281 PRO A C 1 ATOM 2201 O O . PRO A 1 281 ? 70.890 132.474 22.438 1.00 64.21 ? 281 PRO A O 1 ATOM 2202 C CB . PRO A 1 281 ? 74.197 131.875 22.868 1.00 64.97 ? 281 PRO A CB 1 ATOM 2203 C CG . PRO A 1 281 ? 74.859 130.542 22.787 1.00 64.85 ? 281 PRO A CG 1 ATOM 2204 C CD . PRO A 1 281 ? 74.366 129.769 23.980 1.00 64.87 ? 281 PRO A CD 1 ATOM 2205 N N . TYR A 1 282 ? 71.646 130.435 21.767 1.00 63.04 ? 282 TYR A N 1 ATOM 2206 C CA . TYR A 1 282 ? 70.565 130.211 20.807 1.00 62.47 ? 282 TYR A CA 1 ATOM 2207 C C . TYR A 1 282 ? 70.005 128.781 20.917 1.00 61.50 ? 282 TYR A C 1 ATOM 2208 O O . TYR A 1 282 ? 70.692 127.802 20.590 1.00 62.98 ? 282 TYR A O 1 ATOM 2209 C CB . TYR A 1 282 ? 71.015 130.536 19.354 1.00 62.29 ? 282 TYR A CB 1 ATOM 2210 C CG . TYR A 1 282 ? 69.958 131.276 18.551 0.10 62.37 ? 282 TYR A CG 1 ATOM 2211 C CD1 . TYR A 1 282 ? 69.284 130.628 17.495 0.10 62.34 ? 282 TYR A CD1 1 ATOM 2212 C CD2 . TYR A 1 282 ? 69.626 132.625 18.855 0.10 62.56 ? 282 TYR A CD2 1 ATOM 2213 C CE1 . TYR A 1 282 ? 68.313 131.302 16.756 0.10 62.31 ? 282 TYR A CE1 1 ATOM 2214 C CE2 . TYR A 1 282 ? 68.652 133.307 18.125 0.10 62.42 ? 282 TYR A CE2 1 ATOM 2215 C CZ . TYR A 1 282 ? 68.000 132.637 17.078 0.10 62.46 ? 282 TYR A CZ 1 ATOM 2216 O OH . TYR A 1 282 ? 67.036 133.301 16.349 0.10 62.56 ? 282 TYR A OH 1 ATOM 2217 N N . GLY A 1 283 ? 68.769 128.658 21.389 1.00 59.30 ? 283 GLY A N 1 ATOM 2218 C CA . GLY A 1 283 ? 68.108 127.355 21.418 1.00 55.94 ? 283 GLY A CA 1 ATOM 2219 C C . GLY A 1 283 ? 67.191 127.159 20.220 1.00 53.52 ? 283 GLY A C 1 ATOM 2220 O O . GLY A 1 283 ? 66.921 128.097 19.473 1.00 53.42 ? 283 GLY A O 1 ATOM 2221 N N . THR A 1 284 ? 66.719 125.935 20.030 1.00 50.42 ? 284 THR A N 1 ATOM 2222 C CA . THR A 1 284 ? 65.721 125.652 19.007 1.00 47.95 ? 284 THR A CA 1 ATOM 2223 C C . THR A 1 284 ? 64.502 125.051 19.730 1.00 46.27 ? 284 THR A C 1 ATOM 2224 O O . THR A 1 284 ? 64.567 124.797 20.946 1.00 45.25 ? 284 THR A O 1 ATOM 2225 C CB . THR A 1 284 ? 66.272 124.653 17.958 1.00 47.62 ? 284 THR A CB 1 ATOM 2226 O OG1 . THR A 1 284 ? 66.393 123.374 18.576 1.00 47.34 ? 284 THR A OG1 1 ATOM 2227 C CG2 . THR A 1 284 ? 67.697 124.981 17.553 1.00 47.11 ? 284 THR A CG2 1 ATOM 2228 N N . PRO A 1 285 ? 63.401 124.821 19.010 1.00 45.11 ? 285 PRO A N 1 ATOM 2229 C CA . PRO A 1 285 ? 62.240 124.117 19.604 1.00 45.28 ? 285 PRO A CA 1 ATOM 2230 C C . PRO A 1 285 ? 62.572 122.690 20.074 1.00 45.86 ? 285 PRO A C 1 ATOM 2231 O O . PRO A 1 285 ? 61.750 122.062 20.722 1.00 46.86 ? 285 PRO A O 1 ATOM 2232 C CB . PRO A 1 285 ? 61.255 124.068 18.456 1.00 44.78 ? 285 PRO A CB 1 ATOM 2233 C CG . PRO A 1 285 ? 61.682 125.210 17.541 1.00 43.58 ? 285 PRO A CG 1 ATOM 2234 C CD . PRO A 1 285 ? 63.145 125.232 17.616 1.00 44.08 ? 285 PRO A CD 1 ATOM 2235 N N . LEU A 1 286 ? 63.760 122.190 19.727 1.00 46.11 ? 286 LEU A N 1 ATOM 2236 C CA . LEU A 1 286 ? 64.197 120.838 20.074 1.00 46.03 ? 286 LEU A CA 1 ATOM 2237 C C . LEU A 1 286 ? 65.364 120.878 21.065 1.00 45.95 ? 286 LEU A C 1 ATOM 2238 O O . LEU A 1 286 ? 65.978 119.859 21.364 1.00 46.01 ? 286 LEU A O 1 ATOM 2239 C CB . LEU A 1 286 ? 64.604 120.049 18.821 1.00 46.15 ? 286 LEU A CB 1 ATOM 2240 C CG . LEU A 1 286 ? 63.416 119.565 17.997 1.00 45.59 ? 286 LEU A CG 1 ATOM 2241 C CD1 . LEU A 1 286 ? 63.305 120.372 16.777 1.00 42.70 ? 286 LEU A CD1 1 ATOM 2242 C CD2 . LEU A 1 286 ? 63.556 118.106 17.656 1.00 44.91 ? 286 LEU A CD2 1 ATOM 2243 N N . SER A 1 287 ? 65.634 122.055 21.608 1.00 45.67 ? 287 SER A N 1 ATOM 2244 C CA . SER A 1 287 ? 66.666 122.215 22.628 1.00 45.07 ? 287 SER A CA 1 ATOM 2245 C C . SER A 1 287 ? 66.508 121.289 23.832 1.00 43.52 ? 287 SER A C 1 ATOM 2246 O O . SER A 1 287 ? 65.440 121.110 24.381 1.00 44.48 ? 287 SER A O 1 ATOM 2247 C CB . SER A 1 287 ? 66.719 123.679 23.097 1.00 44.96 ? 287 SER A CB 1 ATOM 2248 O OG . SER A 1 287 ? 67.692 124.376 22.347 1.00 47.11 ? 287 SER A OG 1 ATOM 2249 N N . VAL A 1 288 ? 67.610 120.728 24.253 1.00 42.32 ? 288 VAL A N 1 ATOM 2250 C CA . VAL A 1 288 ? 67.633 119.871 25.401 1.00 41.24 ? 288 VAL A CA 1 ATOM 2251 C C . VAL A 1 288 ? 68.753 120.480 26.193 1.00 41.89 ? 288 VAL A C 1 ATOM 2252 O O . VAL A 1 288 ? 69.894 120.029 26.129 1.00 42.47 ? 288 VAL A O 1 ATOM 2253 C CB . VAL A 1 288 ? 67.932 118.381 25.022 1.00 41.00 ? 288 VAL A CB 1 ATOM 2254 C CG1 . VAL A 1 288 ? 68.260 117.550 26.262 1.00 36.21 ? 288 VAL A CG1 1 ATOM 2255 C CG2 . VAL A 1 288 ? 66.727 117.776 24.233 1.00 38.84 ? 288 VAL A CG2 1 ATOM 2256 N N . ASN A 1 289 ? 68.415 121.524 26.927 1.00 42.07 ? 289 ASN A N 1 ATOM 2257 C CA . ASN A 1 289 ? 69.391 122.285 27.685 1.00 42.43 ? 289 ASN A CA 1 ATOM 2258 C C . ASN A 1 289 ? 70.187 121.391 28.612 1.00 40.55 ? 289 ASN A C 1 ATOM 2259 O O . ASN A 1 289 ? 71.406 121.474 28.604 1.00 40.35 ? 289 ASN A O 1 ATOM 2260 C CB . ASN A 1 289 ? 68.707 123.402 28.509 1.00 43.38 ? 289 ASN A CB 1 ATOM 2261 C CG . ASN A 1 289 ? 68.021 124.450 27.634 1.00 46.59 ? 289 ASN A CG 1 ATOM 2262 O OD1 . ASN A 1 289 ? 68.594 124.915 26.643 1.00 48.61 ? 289 ASN A OD1 1 ATOM 2263 N ND2 . ASN A 1 289 ? 66.758 124.794 27.985 1.00 47.34 ? 289 ASN A ND2 1 ATOM 2264 N N . PHE A 1 290 ? 69.479 120.576 29.414 1.00 39.05 ? 290 PHE A N 1 ATOM 2265 C CA . PHE A 1 290 ? 70.062 119.670 30.413 1.00 38.17 ? 290 PHE A CA 1 ATOM 2266 C C . PHE A 1 290 ? 69.651 118.239 30.131 1.00 37.72 ? 290 PHE A C 1 ATOM 2267 O O . PHE A 1 290 ? 68.499 117.856 30.365 1.00 38.81 ? 290 PHE A O 1 ATOM 2268 C CB . PHE A 1 290 ? 69.648 120.068 31.854 1.00 37.22 ? 290 PHE A CB 1 ATOM 2269 C CG . PHE A 1 290 ? 70.186 121.402 32.242 1.00 40.54 ? 290 PHE A CG 1 ATOM 2270 C CD1 . PHE A 1 290 ? 71.516 121.519 32.693 1.00 38.59 ? 290 PHE A CD1 1 ATOM 2271 C CD2 . PHE A 1 290 ? 69.435 122.560 31.995 1.00 38.20 ? 290 PHE A CD2 1 ATOM 2272 C CE1 . PHE A 1 290 ? 72.058 122.761 32.965 1.00 42.26 ? 290 PHE A CE1 1 ATOM 2273 C CE2 . PHE A 1 290 ? 69.964 123.830 32.288 1.00 39.56 ? 290 PHE A CE2 1 ATOM 2274 C CZ . PHE A 1 290 ? 71.268 123.940 32.758 1.00 39.75 ? 290 PHE A CZ 1 ATOM 2275 N N . GLY A 1 291 ? 70.596 117.443 29.674 1.00 37.27 ? 291 GLY A N 1 ATOM 2276 C CA . GLY A 1 291 ? 70.323 116.055 29.302 1.00 37.57 ? 291 GLY A CA 1 ATOM 2277 C C . GLY A 1 291 ? 71.414 115.085 29.663 1.00 37.44 ? 291 GLY A C 1 ATOM 2278 O O . GLY A 1 291 ? 72.347 115.425 30.401 1.00 38.62 ? 291 GLY A O 1 ATOM 2279 N N . PRO A 1 292 ? 71.285 113.850 29.217 1.00 36.82 ? 292 PRO A N 1 ATOM 2280 C CA . PRO A 1 292 ? 72.321 112.839 29.507 1.00 36.45 ? 292 PRO A CA 1 ATOM 2281 C C . PRO A 1 292 ? 73.721 113.279 29.104 1.00 36.05 ? 292 PRO A C 1 ATOM 2282 O O . PRO A 1 292 ? 73.896 113.915 28.072 1.00 35.52 ? 292 PRO A O 1 ATOM 2283 C CB . PRO A 1 292 ? 71.883 111.616 28.675 1.00 35.41 ? 292 PRO A CB 1 ATOM 2284 C CG . PRO A 1 292 ? 70.422 111.799 28.430 1.00 36.08 ? 292 PRO A CG 1 ATOM 2285 C CD . PRO A 1 292 ? 70.131 113.295 28.488 1.00 36.03 ? 292 PRO A CD 1 ATOM 2286 N N . THR A 1 293 ? 74.702 112.961 29.936 1.00 36.30 ? 293 THR A N 1 ATOM 2287 C CA . THR A 1 293 ? 76.101 113.199 29.612 1.00 36.80 ? 293 THR A CA 1 ATOM 2288 C C . THR A 1 293 ? 76.902 111.907 29.768 1.00 37.13 ? 293 THR A C 1 ATOM 2289 O O . THR A 1 293 ? 76.463 110.946 30.408 1.00 38.44 ? 293 THR A O 1 ATOM 2290 C CB . THR A 1 293 ? 76.759 114.239 30.564 1.00 37.11 ? 293 THR A CB 1 ATOM 2291 O OG1 . THR A 1 293 ? 76.283 114.046 31.908 1.00 34.87 ? 293 THR A OG1 1 ATOM 2292 C CG2 . THR A 1 293 ? 76.354 115.592 30.226 1.00 38.80 ? 293 THR A CG2 1 ATOM 2293 N N . VAL A 1 294 ? 78.115 111.908 29.253 1.00 37.25 ? 294 VAL A N 1 ATOM 2294 C CA . VAL A 1 294 ? 79.028 110.829 29.588 1.00 38.21 ? 294 VAL A CA 1 ATOM 2295 C C . VAL A 1 294 ? 79.589 111.171 30.975 1.00 39.07 ? 294 VAL A C 1 ATOM 2296 O O . VAL A 1 294 ? 80.451 112.035 31.112 1.00 40.65 ? 294 VAL A O 1 ATOM 2297 C CB . VAL A 1 294 ? 80.136 110.681 28.492 1.00 37.78 ? 294 VAL A CB 1 ATOM 2298 C CG1 . VAL A 1 294 ? 81.153 109.586 28.851 1.00 38.29 ? 294 VAL A CG1 1 ATOM 2299 C CG2 . VAL A 1 294 ? 79.492 110.418 27.133 1.00 37.43 ? 294 VAL A CG2 1 ATOM 2300 N N . ASP A 1 295 ? 79.078 110.508 31.993 1.00 39.88 ? 295 ASP A N 1 ATOM 2301 C CA . ASP A 1 295 ? 79.404 110.819 33.374 1.00 41.62 ? 295 ASP A CA 1 ATOM 2302 C C . ASP A 1 295 ? 80.473 109.853 33.996 1.00 42.76 ? 295 ASP A C 1 ATOM 2303 O O . ASP A 1 295 ? 80.913 110.026 35.146 1.00 43.26 ? 295 ASP A O 1 ATOM 2304 C CB . ASP A 1 295 ? 78.105 110.767 34.194 1.00 40.12 ? 295 ASP A CB 1 ATOM 2305 C CG . ASP A 1 295 ? 77.498 109.398 34.204 1.00 41.37 ? 295 ASP A CG 1 ATOM 2306 O OD1 . ASP A 1 295 ? 77.865 108.592 33.302 1.00 41.76 ? 295 ASP A OD1 1 ATOM 2307 O OD2 . ASP A 1 295 ? 76.673 109.006 35.068 1.00 37.22 ? 295 ASP A OD2 1 ATOM 2308 N N . GLY A 1 296 ? 80.867 108.822 33.248 1.00 43.28 ? 296 GLY A N 1 ATOM 2309 C CA . GLY A 1 296 ? 81.777 107.811 33.771 1.00 42.72 ? 296 GLY A CA 1 ATOM 2310 C C . GLY A 1 296 ? 81.138 106.882 34.787 1.00 42.79 ? 296 GLY A C 1 ATOM 2311 O O . GLY A 1 296 ? 81.837 106.165 35.488 1.00 43.37 ? 296 GLY A O 1 ATOM 2312 N N . ASP A 1 297 ? 79.808 106.897 34.887 1.00 42.47 ? 297 ASP A N 1 ATOM 2313 C CA . ASP A 1 297 ? 79.097 106.106 35.889 1.00 41.22 ? 297 ASP A CA 1 ATOM 2314 C C . ASP A 1 297 ? 77.922 105.358 35.224 1.00 41.21 ? 297 ASP A C 1 ATOM 2315 O O . ASP A 1 297 ? 78.027 104.171 34.961 1.00 41.55 ? 297 ASP A O 1 ATOM 2316 C CB . ASP A 1 297 ? 78.636 107.020 37.056 1.00 40.75 ? 297 ASP A CB 1 ATOM 2317 C CG . ASP A 1 297 ? 78.081 106.240 38.216 1.00 42.21 ? 297 ASP A CG 1 ATOM 2318 O OD1 . ASP A 1 297 ? 78.010 104.988 38.119 1.00 43.54 ? 297 ASP A OD1 1 ATOM 2319 O OD2 . ASP A 1 297 ? 77.696 106.779 39.285 1.00 46.88 ? 297 ASP A OD2 1 ATOM 2320 N N . PHE A 1 298 ? 76.811 106.055 34.938 1.00 40.24 ? 298 PHE A N 1 ATOM 2321 C CA . PHE A 1 298 ? 75.744 105.491 34.120 1.00 39.17 ? 298 PHE A CA 1 ATOM 2322 C C . PHE A 1 298 ? 76.277 105.218 32.696 1.00 39.26 ? 298 PHE A C 1 ATOM 2323 O O . PHE A 1 298 ? 75.976 104.178 32.110 1.00 39.06 ? 298 PHE A O 1 ATOM 2324 C CB . PHE A 1 298 ? 74.549 106.448 34.017 1.00 38.31 ? 298 PHE A CB 1 ATOM 2325 C CG . PHE A 1 298 ? 73.336 105.834 33.372 1.00 36.33 ? 298 PHE A CG 1 ATOM 2326 C CD1 . PHE A 1 298 ? 73.089 106.017 32.005 1.00 36.41 ? 298 PHE A CD1 1 ATOM 2327 C CD2 . PHE A 1 298 ? 72.450 105.077 34.115 1.00 32.89 ? 298 PHE A CD2 1 ATOM 2328 C CE1 . PHE A 1 298 ? 71.954 105.462 31.383 1.00 34.01 ? 298 PHE A CE1 1 ATOM 2329 C CE2 . PHE A 1 298 ? 71.327 104.513 33.516 1.00 32.50 ? 298 PHE A CE2 1 ATOM 2330 C CZ . PHE A 1 298 ? 71.077 104.728 32.131 1.00 34.28 ? 298 PHE A CZ 1 ATOM 2331 N N . LEU A 1 299 ? 77.064 106.142 32.182 1.00 38.93 ? 299 LEU A N 1 ATOM 2332 C CA . LEU A 1 299 ? 77.525 106.093 30.815 1.00 40.89 ? 299 LEU A CA 1 ATOM 2333 C C . LEU A 1 299 ? 79.061 106.152 30.829 1.00 41.85 ? 299 LEU A C 1 ATOM 2334 O O . LEU A 1 299 ? 79.669 107.187 31.164 1.00 41.53 ? 299 LEU A O 1 ATOM 2335 C CB . LEU A 1 299 ? 76.982 107.289 30.061 1.00 40.40 ? 299 LEU A CB 1 ATOM 2336 C CG . LEU A 1 299 ? 76.257 107.141 28.721 1.00 45.00 ? 299 LEU A CG 1 ATOM 2337 C CD1 . LEU A 1 299 ? 76.014 108.501 28.072 1.00 44.12 ? 299 LEU A CD1 1 ATOM 2338 C CD2 . LEU A 1 299 ? 76.960 106.206 27.703 1.00 47.39 ? 299 LEU A CD2 1 ATOM 2339 N N . THR A 1 300 ? 79.694 105.042 30.454 1.00 42.61 ? 300 THR A N 1 ATOM 2340 C CA . THR A 1 300 ? 81.167 104.956 30.554 1.00 44.19 ? 300 THR A CA 1 ATOM 2341 C C . THR A 1 300 ? 81.969 105.504 29.393 1.00 43.50 ? 300 THR A C 1 ATOM 2342 O O . THR A 1 300 ? 83.167 105.709 29.524 1.00 44.21 ? 300 THR A O 1 ATOM 2343 C CB . THR A 1 300 ? 81.585 103.534 30.827 1.00 44.90 ? 300 THR A CB 1 ATOM 2344 O OG1 . THR A 1 300 ? 81.297 102.740 29.666 1.00 46.42 ? 300 THR A OG1 1 ATOM 2345 C CG2 . THR A 1 300 ? 80.672 102.942 31.945 1.00 45.61 ? 300 THR A CG2 1 ATOM 2346 N N . ASP A 1 301 ? 81.326 105.776 28.271 1.00 42.98 ? 301 ASP A N 1 ATOM 2347 C CA . ASP A 1 301 ? 82.057 106.302 27.126 1.00 43.07 ? 301 ASP A CA 1 ATOM 2348 C C . ASP A 1 301 ? 81.049 106.938 26.182 1.00 42.84 ? 301 ASP A C 1 ATOM 2349 O O . ASP A 1 301 ? 79.873 106.813 26.389 1.00 42.75 ? 301 ASP A O 1 ATOM 2350 C CB . ASP A 1 301 ? 82.798 105.147 26.446 1.00 42.43 ? 301 ASP A CB 1 ATOM 2351 C CG . ASP A 1 301 ? 83.897 105.614 25.503 1.00 43.91 ? 301 ASP A CG 1 ATOM 2352 O OD1 . ASP A 1 301 ? 84.630 104.715 24.993 1.00 44.71 ? 301 ASP A OD1 1 ATOM 2353 O OD2 . ASP A 1 301 ? 84.076 106.820 25.199 1.00 40.60 ? 301 ASP A OD2 1 ATOM 2354 N N . MET A 1 302 ? 81.502 107.640 25.164 1.00 43.10 ? 302 MET A N 1 ATOM 2355 C CA . MET A 1 302 ? 80.571 108.231 24.228 1.00 43.96 ? 302 MET A CA 1 ATOM 2356 C C . MET A 1 302 ? 79.706 107.139 23.647 1.00 43.07 ? 302 MET A C 1 ATOM 2357 O O . MET A 1 302 ? 80.206 106.145 23.178 1.00 43.33 ? 302 MET A O 1 ATOM 2358 C CB . MET A 1 302 ? 81.318 109.006 23.171 1.00 45.24 ? 302 MET A CB 1 ATOM 2359 C CG . MET A 1 302 ? 82.134 110.158 23.771 1.00 48.21 ? 302 MET A CG 1 ATOM 2360 S SD . MET A 1 302 ? 83.118 110.887 22.451 1.00 58.74 ? 302 MET A SD 1 ATOM 2361 C CE . MET A 1 302 ? 81.790 111.855 21.634 1.00 59.26 ? 302 MET A CE 1 ATOM 2362 N N . PRO A 1 303 ? 78.397 107.273 23.779 1.00 42.97 ? 303 PRO A N 1 ATOM 2363 C CA . PRO A 1 303 ? 77.501 106.185 23.396 1.00 42.22 ? 303 PRO A CA 1 ATOM 2364 C C . PRO A 1 303 ? 77.617 105.781 21.915 1.00 40.79 ? 303 PRO A C 1 ATOM 2365 O O . PRO A 1 303 ? 77.435 104.631 21.599 1.00 40.27 ? 303 PRO A O 1 ATOM 2366 C CB . PRO A 1 303 ? 76.091 106.696 23.775 1.00 42.70 ? 303 PRO A CB 1 ATOM 2367 C CG . PRO A 1 303 ? 76.249 108.130 24.124 1.00 43.96 ? 303 PRO A CG 1 ATOM 2368 C CD . PRO A 1 303 ? 77.695 108.436 24.353 1.00 42.29 ? 303 PRO A CD 1 ATOM 2369 N N . ASP A 1 304 ? 77.975 106.683 21.034 1.00 40.00 ? 304 ASP A N 1 ATOM 2370 C CA . ASP A 1 304 ? 78.195 106.282 19.644 1.00 41.75 ? 304 ASP A CA 1 ATOM 2371 C C . ASP A 1 304 ? 79.268 105.204 19.522 1.00 41.02 ? 304 ASP A C 1 ATOM 2372 O O . ASP A 1 304 ? 79.208 104.384 18.598 1.00 40.31 ? 304 ASP A O 1 ATOM 2373 C CB . ASP A 1 304 ? 78.610 107.474 18.770 1.00 43.22 ? 304 ASP A CB 1 ATOM 2374 C CG . ASP A 1 304 ? 79.598 108.434 19.476 1.00 49.12 ? 304 ASP A CG 1 ATOM 2375 O OD1 . ASP A 1 304 ? 79.355 108.808 20.661 1.00 54.68 ? 304 ASP A OD1 1 ATOM 2376 O OD2 . ASP A 1 304 ? 80.603 108.931 18.894 1.00 54.42 ? 304 ASP A OD2 1 ATOM 2377 N N . ILE A 1 305 ? 80.250 105.238 20.437 1.00 38.93 ? 305 ILE A N 1 ATOM 2378 C CA . ILE A 1 305 ? 81.411 104.345 20.365 1.00 38.69 ? 305 ILE A CA 1 ATOM 2379 C C . ILE A 1 305 ? 80.954 102.978 20.862 1.00 37.69 ? 305 ILE A C 1 ATOM 2380 O O . ILE A 1 305 ? 81.228 101.965 20.214 1.00 35.76 ? 305 ILE A O 1 ATOM 2381 C CB . ILE A 1 305 ? 82.652 104.888 21.184 1.00 38.25 ? 305 ILE A CB 1 ATOM 2382 C CG1 . ILE A 1 305 ? 83.028 106.303 20.702 1.00 40.12 ? 305 ILE A CG1 1 ATOM 2383 C CG2 . ILE A 1 305 ? 83.833 103.890 21.093 1.00 39.03 ? 305 ILE A CG2 1 ATOM 2384 C CD1 . ILE A 1 305 ? 84.278 106.966 21.392 1.00 41.69 ? 305 ILE A CD1 1 ATOM 2385 N N . LEU A 1 306 ? 80.211 102.987 21.973 1.00 36.68 ? 306 LEU A N 1 ATOM 2386 C CA . LEU A 1 306 ? 79.562 101.777 22.517 1.00 37.57 ? 306 LEU A CA 1 ATOM 2387 C C . LEU A 1 306 ? 78.687 101.025 21.492 1.00 37.60 ? 306 LEU A C 1 ATOM 2388 O O . LEU A 1 306 ? 78.751 99.802 21.379 1.00 38.09 ? 306 LEU A O 1 ATOM 2389 C CB . LEU A 1 306 ? 78.748 102.126 23.779 1.00 35.85 ? 306 LEU A CB 1 ATOM 2390 C CG . LEU A 1 306 ? 79.626 102.710 24.908 1.00 37.34 ? 306 LEU A CG 1 ATOM 2391 C CD1 . LEU A 1 306 ? 78.766 103.240 26.067 1.00 34.68 ? 306 LEU A CD1 1 ATOM 2392 C CD2 . LEU A 1 306 ? 80.642 101.680 25.488 1.00 36.15 ? 306 LEU A CD2 1 ATOM 2393 N N . LEU A 1 307 ? 77.846 101.768 20.765 1.00 38.39 ? 307 LEU A N 1 ATOM 2394 C CA . LEU A 1 307 ? 76.951 101.181 19.764 1.00 37.98 ? 307 LEU A CA 1 ATOM 2395 C C . LEU A 1 307 ? 77.772 100.583 18.612 1.00 38.11 ? 307 LEU A C 1 ATOM 2396 O O . LEU A 1 307 ? 77.556 99.433 18.184 1.00 38.50 ? 307 LEU A O 1 ATOM 2397 C CB . LEU A 1 307 ? 76.030 102.259 19.196 1.00 37.69 ? 307 LEU A CB 1 ATOM 2398 C CG . LEU A 1 307 ? 75.019 101.793 18.120 1.00 37.68 ? 307 LEU A CG 1 ATOM 2399 C CD1 . LEU A 1 307 ? 74.087 100.664 18.667 1.00 37.77 ? 307 LEU A CD1 1 ATOM 2400 C CD2 . LEU A 1 307 ? 74.196 102.985 17.621 1.00 36.12 ? 307 LEU A CD2 1 ATOM 2401 N N . GLU A 1 308 ? 78.698 101.382 18.099 1.00 37.84 ? 308 GLU A N 1 ATOM 2402 C CA . GLU A 1 308 ? 79.525 100.960 16.958 1.00 38.58 ? 308 GLU A CA 1 ATOM 2403 C C . GLU A 1 308 ? 80.277 99.662 17.261 1.00 38.14 ? 308 GLU A C 1 ATOM 2404 O O . GLU A 1 308 ? 80.404 98.796 16.393 1.00 38.41 ? 308 GLU A O 1 ATOM 2405 C CB . GLU A 1 308 ? 80.486 102.084 16.550 1.00 37.83 ? 308 GLU A CB 1 ATOM 2406 C CG . GLU A 1 308 ? 81.438 101.701 15.444 1.00 40.31 ? 308 GLU A CG 1 ATOM 2407 C CD . GLU A 1 308 ? 80.756 101.446 14.115 1.00 45.73 ? 308 GLU A CD 1 ATOM 2408 O OE1 . GLU A 1 308 ? 81.292 100.648 13.299 1.00 48.73 ? 308 GLU A OE1 1 ATOM 2409 O OE2 . GLU A 1 308 ? 79.704 102.067 13.869 1.00 45.86 ? 308 GLU A OE2 1 ATOM 2410 N N . LEU A 1 309 ? 80.711 99.512 18.512 1.00 37.41 ? 309 LEU A N 1 ATOM 2411 C CA . LEU A 1 309 ? 81.640 98.423 18.897 1.00 37.14 ? 309 LEU A CA 1 ATOM 2412 C C . LEU A 1 309 ? 80.976 97.324 19.672 1.00 36.78 ? 309 LEU A C 1 ATOM 2413 O O . LEU A 1 309 ? 81.653 96.438 20.192 1.00 36.74 ? 309 LEU A O 1 ATOM 2414 C CB . LEU A 1 309 ? 82.876 98.970 19.663 1.00 35.67 ? 309 LEU A CB 1 ATOM 2415 C CG . LEU A 1 309 ? 83.736 99.884 18.776 1.00 34.17 ? 309 LEU A CG 1 ATOM 2416 C CD1 . LEU A 1 309 ? 84.897 100.419 19.563 1.00 33.64 ? 309 LEU A CD1 1 ATOM 2417 C CD2 . LEU A 1 309 ? 84.234 99.183 17.408 1.00 29.48 ? 309 LEU A CD2 1 ATOM 2418 N N . GLY A 1 310 ? 79.648 97.390 19.767 1.00 37.56 ? 310 GLY A N 1 ATOM 2419 C CA . GLY A 1 310 ? 78.867 96.248 20.237 1.00 37.48 ? 310 GLY A CA 1 ATOM 2420 C C . GLY A 1 310 ? 78.813 96.129 21.721 1.00 38.82 ? 310 GLY A C 1 ATOM 2421 O O . GLY A 1 310 ? 78.571 95.023 22.223 1.00 38.55 ? 310 GLY A O 1 ATOM 2422 N N . GLN A 1 311 ? 79.037 97.241 22.442 1.00 38.66 ? 311 GLN A N 1 ATOM 2423 C CA . GLN A 1 311 ? 79.064 97.175 23.901 1.00 39.20 ? 311 GLN A CA 1 ATOM 2424 C C . GLN A 1 311 ? 77.705 97.615 24.454 1.00 38.95 ? 311 GLN A C 1 ATOM 2425 O O . GLN A 1 311 ? 77.488 98.792 24.786 1.00 38.62 ? 311 GLN A O 1 ATOM 2426 C CB . GLN A 1 311 ? 80.204 98.020 24.498 1.00 40.05 ? 311 GLN A CB 1 ATOM 2427 C CG . GLN A 1 311 ? 81.550 97.840 23.768 1.00 42.27 ? 311 GLN A CG 1 ATOM 2428 C CD . GLN A 1 311 ? 82.060 96.419 23.904 1.00 44.75 ? 311 GLN A CD 1 ATOM 2429 O OE1 . GLN A 1 311 ? 82.276 95.726 22.892 1.00 46.12 ? 311 GLN A OE1 1 ATOM 2430 N NE2 . GLN A 1 311 ? 82.189 95.952 25.147 1.00 41.62 ? 311 GLN A NE2 1 ATOM 2431 N N . PHE A 1 312 ? 76.780 96.654 24.494 1.00 37.75 ? 312 PHE A N 1 ATOM 2432 C CA . PHE A 1 312 ? 75.414 96.876 24.929 1.00 36.93 ? 312 PHE A CA 1 ATOM 2433 C C . PHE A 1 312 ? 74.775 95.543 25.209 1.00 37.23 ? 312 PHE A C 1 ATOM 2434 O O . PHE A 1 312 ? 75.311 94.495 24.795 1.00 36.92 ? 312 PHE A O 1 ATOM 2435 C CB . PHE A 1 312 ? 74.597 97.661 23.885 1.00 35.64 ? 312 PHE A CB 1 ATOM 2436 C CG . PHE A 1 312 ? 74.695 97.126 22.470 1.00 35.04 ? 312 PHE A CG 1 ATOM 2437 C CD1 . PHE A 1 312 ? 74.007 96.001 22.082 1.00 34.03 ? 312 PHE A CD1 1 ATOM 2438 C CD2 . PHE A 1 312 ? 75.433 97.798 21.518 1.00 35.72 ? 312 PHE A CD2 1 ATOM 2439 C CE1 . PHE A 1 312 ? 74.076 95.535 20.756 1.00 34.87 ? 312 PHE A CE1 1 ATOM 2440 C CE2 . PHE A 1 312 ? 75.512 97.352 20.201 1.00 35.73 ? 312 PHE A CE2 1 ATOM 2441 C CZ . PHE A 1 312 ? 74.801 96.196 19.824 1.00 34.08 ? 312 PHE A CZ 1 ATOM 2442 N N . LYS A 1 313 ? 73.619 95.585 25.860 1.00 35.82 ? 313 LYS A N 1 ATOM 2443 C CA . LYS A 1 313 ? 72.934 94.373 26.260 1.00 36.20 ? 313 LYS A CA 1 ATOM 2444 C C . LYS A 1 313 ? 72.403 93.675 24.991 1.00 36.39 ? 313 LYS A C 1 ATOM 2445 O O . LYS A 1 313 ? 71.779 94.321 24.142 1.00 35.84 ? 313 LYS A O 1 ATOM 2446 C CB . LYS A 1 313 ? 71.771 94.743 27.196 1.00 36.08 ? 313 LYS A CB 1 ATOM 2447 C CG . LYS A 1 313 ? 70.912 93.578 27.629 1.00 36.51 ? 313 LYS A CG 1 ATOM 2448 C CD . LYS A 1 313 ? 69.653 94.080 28.300 1.00 40.08 ? 313 LYS A CD 1 ATOM 2449 C CE . LYS A 1 313 ? 68.738 92.932 28.743 1.00 39.55 ? 313 LYS A CE 1 ATOM 2450 N NZ . LYS A 1 313 ? 69.352 92.212 29.894 1.00 37.81 ? 313 LYS A NZ 1 ATOM 2451 N N . LYS A 1 314 ? 72.652 92.371 24.887 1.00 35.61 ? 314 LYS A N 1 ATOM 2452 C CA . LYS A 1 314 ? 72.330 91.582 23.714 1.00 35.96 ? 314 LYS A CA 1 ATOM 2453 C C . LYS A 1 314 ? 70.934 91.005 23.953 1.00 36.07 ? 314 LYS A C 1 ATOM 2454 O O . LYS A 1 314 ? 70.765 90.183 24.846 1.00 37.03 ? 314 LYS A O 1 ATOM 2455 C CB . LYS A 1 314 ? 73.376 90.443 23.556 1.00 36.57 ? 314 LYS A CB 1 ATOM 2456 C CG . LYS A 1 314 ? 74.836 90.910 23.244 1.00 37.02 ? 314 LYS A CG 1 ATOM 2457 C CD . LYS A 1 314 ? 74.840 92.035 22.168 1.00 40.58 ? 314 LYS A CD 1 ATOM 2458 C CE . LYS A 1 314 ? 76.220 92.501 21.702 1.00 39.90 ? 314 LYS A CE 1 ATOM 2459 N NZ . LYS A 1 314 ? 77.041 92.983 22.827 1.00 42.24 ? 314 LYS A NZ 1 ATOM 2460 N N . THR A 1 315 ? 69.929 91.531 23.246 1.00 35.71 ? 315 THR A N 1 ATOM 2461 C CA . THR A 1 315 ? 68.495 91.185 23.457 1.00 35.02 ? 315 THR A CA 1 ATOM 2462 C C . THR A 1 315 ? 67.733 91.678 22.257 1.00 35.11 ? 315 THR A C 1 ATOM 2463 O O . THR A 1 315 ? 68.336 92.278 21.374 1.00 35.49 ? 315 THR A O 1 ATOM 2464 C CB . THR A 1 315 ? 67.935 91.775 24.775 1.00 35.39 ? 315 THR A CB 1 ATOM 2465 O OG1 . THR A 1 315 ? 66.610 91.269 25.013 1.00 32.37 ? 315 THR A OG1 1 ATOM 2466 C CG2 . THR A 1 315 ? 67.757 93.343 24.667 1.00 33.55 ? 315 THR A CG2 1 ATOM 2467 N N . GLN A 1 316 ? 66.440 91.377 22.177 1.00 35.02 ? 316 GLN A N 1 ATOM 2468 C CA . GLN A 1 316 ? 65.603 91.814 21.057 1.00 35.36 ? 316 GLN A CA 1 ATOM 2469 C C . GLN A 1 316 ? 65.160 93.269 21.270 1.00 34.75 ? 316 GLN A C 1 ATOM 2470 O O . GLN A 1 316 ? 64.868 93.668 22.397 1.00 33.75 ? 316 GLN A O 1 ATOM 2471 C CB . GLN A 1 316 ? 64.331 90.904 20.879 1.00 34.86 ? 316 GLN A CB 1 ATOM 2472 C CG . GLN A 1 316 ? 64.612 89.378 20.763 1.00 36.18 ? 316 GLN A CG 1 ATOM 2473 C CD . GLN A 1 316 ? 65.085 88.776 22.099 1.00 37.11 ? 316 GLN A CD 1 ATOM 2474 O OE1 . GLN A 1 316 ? 64.528 89.049 23.156 1.00 34.56 ? 316 GLN A OE1 1 ATOM 2475 N NE2 . GLN A 1 316 ? 66.162 88.024 22.044 1.00 40.57 ? 316 GLN A NE2 1 ATOM 2476 N N . ILE A 1 317 ? 65.078 94.036 20.187 1.00 33.33 ? 317 ILE A N 1 ATOM 2477 C CA . ILE A 1 317 ? 64.534 95.396 20.253 1.00 32.92 ? 317 ILE A CA 1 ATOM 2478 C C . ILE A 1 317 ? 63.359 95.609 19.281 1.00 32.94 ? 317 ILE A C 1 ATOM 2479 O O . ILE A 1 317 ? 63.294 95.014 18.195 1.00 32.66 ? 317 ILE A O 1 ATOM 2480 C CB . ILE A 1 317 ? 65.613 96.467 19.997 1.00 32.99 ? 317 ILE A CB 1 ATOM 2481 C CG1 . ILE A 1 317 ? 66.253 96.252 18.605 1.00 33.81 ? 317 ILE A CG1 1 ATOM 2482 C CG2 . ILE A 1 317 ? 66.629 96.467 21.110 1.00 32.70 ? 317 ILE A CG2 1 ATOM 2483 C CD1 . ILE A 1 317 ? 67.189 97.387 18.068 1.00 31.22 ? 317 ILE A CD1 1 ATOM 2484 N N . LEU A 1 318 ? 62.423 96.450 19.682 1.00 31.94 ? 318 LEU A N 1 ATOM 2485 C CA . LEU A 1 318 ? 61.369 96.866 18.765 1.00 31.54 ? 318 LEU A CA 1 ATOM 2486 C C . LEU A 1 318 ? 61.467 98.409 18.657 1.00 31.51 ? 318 LEU A C 1 ATOM 2487 O O . LEU A 1 318 ? 61.466 99.141 19.677 1.00 30.64 ? 318 LEU A O 1 ATOM 2488 C CB . LEU A 1 318 ? 60.032 96.371 19.312 1.00 31.62 ? 318 LEU A CB 1 ATOM 2489 C CG . LEU A 1 318 ? 58.717 96.500 18.517 1.00 34.34 ? 318 LEU A CG 1 ATOM 2490 C CD1 . LEU A 1 318 ? 57.578 95.841 19.309 1.00 33.36 ? 318 LEU A CD1 1 ATOM 2491 C CD2 . LEU A 1 318 ? 58.321 97.923 18.306 1.00 35.10 ? 318 LEU A CD2 1 ATOM 2492 N N . VAL A 1 319 ? 61.620 98.903 17.433 1.00 31.24 ? 319 VAL A N 1 ATOM 2493 C CA . VAL A 1 319 ? 61.930 100.314 17.202 1.00 30.56 ? 319 VAL A CA 1 ATOM 2494 C C . VAL A 1 319 ? 60.968 100.867 16.175 1.00 31.78 ? 319 VAL A C 1 ATOM 2495 O O . VAL A 1 319 ? 60.620 100.174 15.179 1.00 32.24 ? 319 VAL A O 1 ATOM 2496 C CB . VAL A 1 319 ? 63.377 100.519 16.679 1.00 30.91 ? 319 VAL A CB 1 ATOM 2497 C CG1 . VAL A 1 319 ? 63.776 101.998 16.705 1.00 26.57 ? 319 VAL A CG1 1 ATOM 2498 C CG2 . VAL A 1 319 ? 64.384 99.712 17.523 1.00 30.24 ? 319 VAL A CG2 1 ATOM 2499 N N . GLY A 1 320 ? 60.526 102.105 16.371 1.00 30.63 ? 320 GLY A N 1 ATOM 2500 C CA . GLY A 1 320 ? 59.734 102.680 15.298 1.00 31.58 ? 320 GLY A CA 1 ATOM 2501 C C . GLY A 1 320 ? 59.648 104.177 15.346 1.00 32.48 ? 320 GLY A C 1 ATOM 2502 O O . GLY A 1 320 ? 60.092 104.800 16.315 1.00 32.01 ? 320 GLY A O 1 ATOM 2503 N N . VAL A 1 321 ? 59.073 104.741 14.282 1.00 32.00 ? 321 VAL A N 1 ATOM 2504 C CA . VAL A 1 321 ? 58.868 106.175 14.146 1.00 31.65 ? 321 VAL A CA 1 ATOM 2505 C C . VAL A 1 321 ? 57.510 106.417 13.493 1.00 32.19 ? 321 VAL A C 1 ATOM 2506 O O . VAL A 1 321 ? 56.884 105.490 12.958 1.00 32.53 ? 321 VAL A O 1 ATOM 2507 C CB . VAL A 1 321 ? 59.981 106.845 13.256 1.00 31.12 ? 321 VAL A CB 1 ATOM 2508 C CG1 . VAL A 1 321 ? 61.351 106.752 13.994 1.00 30.12 ? 321 VAL A CG1 1 ATOM 2509 C CG2 . VAL A 1 321 ? 59.989 106.154 11.842 1.00 30.38 ? 321 VAL A CG2 1 ATOM 2510 N N . ASN A 1 322 ? 57.086 107.675 13.540 1.00 31.94 ? 322 ASN A N 1 ATOM 2511 C CA . ASN A 1 322 ? 55.852 108.142 12.959 1.00 32.89 ? 322 ASN A CA 1 ATOM 2512 C C . ASN A 1 322 ? 56.138 108.864 11.653 1.00 33.52 ? 322 ASN A C 1 ATOM 2513 O O . ASN A 1 322 ? 57.238 109.407 11.448 1.00 33.42 ? 322 ASN A O 1 ATOM 2514 C CB . ASN A 1 322 ? 55.134 109.068 13.941 1.00 31.70 ? 322 ASN A CB 1 ATOM 2515 C CG . ASN A 1 322 ? 54.689 108.335 15.189 1.00 33.90 ? 322 ASN A CG 1 ATOM 2516 O OD1 . ASN A 1 322 ? 54.912 107.118 15.329 1.00 35.20 ? 322 ASN A OD1 1 ATOM 2517 N ND2 . ASN A 1 322 ? 54.081 109.050 16.104 1.00 31.46 ? 322 ASN A ND2 1 ATOM 2518 N N . LYS A 1 323 ? 55.138 108.884 10.782 1.00 35.01 ? 323 LYS A N 1 ATOM 2519 C CA . LYS A 1 323 ? 55.297 109.443 9.429 1.00 35.40 ? 323 LYS A CA 1 ATOM 2520 C C . LYS A 1 323 ? 55.671 110.930 9.406 1.00 35.55 ? 323 LYS A C 1 ATOM 2521 O O . LYS A 1 323 ? 56.464 111.364 8.541 1.00 35.01 ? 323 LYS A O 1 ATOM 2522 C CB . LYS A 1 323 ? 54.042 109.148 8.588 1.00 35.60 ? 323 LYS A CB 1 ATOM 2523 C CG . LYS A 1 323 ? 53.956 109.878 7.246 1.00 37.78 ? 323 LYS A CG 1 ATOM 2524 C CD . LYS A 1 323 ? 52.775 109.402 6.416 1.00 41.52 ? 323 LYS A CD 1 ATOM 2525 C CE . LYS A 1 323 ? 52.395 110.530 5.409 1.00 50.99 ? 323 LYS A CE 1 ATOM 2526 N NZ . LYS A 1 323 ? 52.030 110.059 4.009 1.00 56.56 ? 323 LYS A NZ 1 ATOM 2527 N N . ASP A 1 324 ? 55.128 111.705 10.346 1.00 36.03 ? 324 ASP A N 1 ATOM 2528 C CA . ASP A 1 324 ? 55.404 113.161 10.413 1.00 36.18 ? 324 ASP A CA 1 ATOM 2529 C C . ASP A 1 324 ? 55.952 113.608 11.773 1.00 36.35 ? 324 ASP A C 1 ATOM 2530 O O . ASP A 1 324 ? 55.402 114.520 12.427 1.00 36.90 ? 324 ASP A O 1 ATOM 2531 C CB . ASP A 1 324 ? 54.135 113.978 10.068 1.00 36.14 ? 324 ASP A CB 1 ATOM 2532 C CG . ASP A 1 324 ? 53.568 113.628 8.696 1.00 38.32 ? 324 ASP A CG 1 ATOM 2533 O OD1 . ASP A 1 324 ? 54.217 113.980 7.678 1.00 37.71 ? 324 ASP A OD1 1 ATOM 2534 O OD2 . ASP A 1 324 ? 52.493 113.007 8.531 1.00 36.46 ? 324 ASP A OD2 1 ATOM 2535 N N . GLU A 1 325 ? 57.064 113.002 12.166 1.00 35.93 ? 325 GLU A N 1 ATOM 2536 C CA . GLU A 1 325 ? 57.796 113.350 13.383 1.00 35.67 ? 325 GLU A CA 1 ATOM 2537 C C . GLU A 1 325 ? 58.099 114.851 13.511 1.00 36.22 ? 325 GLU A C 1 ATOM 2538 O O . GLU A 1 325 ? 57.986 115.429 14.599 1.00 36.01 ? 325 GLU A O 1 ATOM 2539 C CB . GLU A 1 325 ? 59.116 112.589 13.424 1.00 34.56 ? 325 GLU A CB 1 ATOM 2540 C CG . GLU A 1 325 ? 58.939 111.073 13.584 1.00 35.56 ? 325 GLU A CG 1 ATOM 2541 C CD . GLU A 1 325 ? 58.563 110.674 15.007 1.00 35.35 ? 325 GLU A CD 1 ATOM 2542 O OE1 . GLU A 1 325 ? 58.428 111.583 15.867 1.00 33.25 ? 325 GLU A OE1 1 ATOM 2543 O OE2 . GLU A 1 325 ? 58.423 109.459 15.263 1.00 32.70 ? 325 GLU A OE2 1 ATOM 2544 N N . GLY A 1 326 ? 58.481 115.477 12.402 1.00 35.36 ? 326 GLY A N 1 ATOM 2545 C CA . GLY A 1 326 ? 58.950 116.845 12.486 1.00 35.87 ? 326 GLY A CA 1 ATOM 2546 C C . GLY A 1 326 ? 57.932 117.972 12.550 1.00 35.67 ? 326 GLY A C 1 ATOM 2547 O O . GLY A 1 326 ? 58.309 119.078 12.912 1.00 37.58 ? 326 GLY A O 1 ATOM 2548 N N . THR A 1 327 ? 56.681 117.732 12.172 1.00 34.94 ? 327 THR A N 1 ATOM 2549 C CA . THR A 1 327 ? 55.705 118.830 12.058 1.00 36.64 ? 327 THR A CA 1 ATOM 2550 C C . THR A 1 327 ? 55.373 119.622 13.370 1.00 36.71 ? 327 THR A C 1 ATOM 2551 O O . THR A 1 327 ? 55.320 120.849 13.335 1.00 36.30 ? 327 THR A O 1 ATOM 2552 C CB . THR A 1 327 ? 54.419 118.367 11.399 1.00 36.33 ? 327 THR A CB 1 ATOM 2553 O OG1 . THR A 1 327 ? 53.898 117.245 12.122 1.00 34.49 ? 327 THR A OG1 1 ATOM 2554 C CG2 . THR A 1 327 ? 54.678 117.864 9.962 1.00 36.20 ? 327 THR A CG2 1 ATOM 2555 N N . ALA A 1 328 ? 55.133 118.902 14.473 1.00 36.89 ? 328 ALA A N 1 ATOM 2556 C CA . ALA A 1 328 ? 54.876 119.460 15.800 1.00 36.82 ? 328 ALA A CA 1 ATOM 2557 C C . ALA A 1 328 ? 55.804 120.638 16.113 1.00 37.58 ? 328 ALA A C 1 ATOM 2558 O O . ALA A 1 328 ? 55.399 121.594 16.780 1.00 36.30 ? 328 ALA A O 1 ATOM 2559 C CB . ALA A 1 328 ? 55.051 118.368 16.900 1.00 36.35 ? 328 ALA A CB 1 ATOM 2560 N N . PHE A 1 329 ? 57.048 120.573 15.627 1.00 37.11 ? 329 PHE A N 1 ATOM 2561 C CA . PHE A 1 329 ? 58.041 121.521 16.103 1.00 37.93 ? 329 PHE A CA 1 ATOM 2562 C C . PHE A 1 329 ? 58.006 122.846 15.365 1.00 38.53 ? 329 PHE A C 1 ATOM 2563 O O . PHE A 1 329 ? 58.481 123.850 15.883 1.00 38.26 ? 329 PHE A O 1 ATOM 2564 C CB . PHE A 1 329 ? 59.466 120.892 16.164 1.00 37.02 ? 329 PHE A CB 1 ATOM 2565 C CG . PHE A 1 329 ? 59.526 119.686 17.059 1.00 38.05 ? 329 PHE A CG 1 ATOM 2566 C CD1 . PHE A 1 329 ? 59.253 118.409 16.547 1.00 37.89 ? 329 PHE A CD1 1 ATOM 2567 C CD2 . PHE A 1 329 ? 59.797 119.834 18.433 1.00 36.70 ? 329 PHE A CD2 1 ATOM 2568 C CE1 . PHE A 1 329 ? 59.272 117.277 17.392 1.00 37.64 ? 329 PHE A CE1 1 ATOM 2569 C CE2 . PHE A 1 329 ? 59.839 118.728 19.277 1.00 38.18 ? 329 PHE A CE2 1 ATOM 2570 C CZ . PHE A 1 329 ? 59.565 117.441 18.761 1.00 37.65 ? 329 PHE A CZ 1 ATOM 2571 N N . LEU A 1 330 ? 57.429 122.841 14.173 1.00 39.54 ? 330 LEU A N 1 ATOM 2572 C CA . LEU A 1 330 ? 57.476 124.018 13.278 1.00 41.08 ? 330 LEU A CA 1 ATOM 2573 C C . LEU A 1 330 ? 56.665 125.207 13.816 1.00 41.92 ? 330 LEU A C 1 ATOM 2574 O O . LEU A 1 330 ? 56.990 126.353 13.531 1.00 41.58 ? 330 LEU A O 1 ATOM 2575 C CB . LEU A 1 330 ? 56.976 123.634 11.871 1.00 40.61 ? 330 LEU A CB 1 ATOM 2576 C CG . LEU A 1 330 ? 57.622 122.363 11.283 1.00 39.54 ? 330 LEU A CG 1 ATOM 2577 C CD1 . LEU A 1 330 ? 57.013 121.997 9.948 1.00 37.04 ? 330 LEU A CD1 1 ATOM 2578 C CD2 . LEU A 1 330 ? 59.136 122.525 11.203 1.00 36.35 ? 330 LEU A CD2 1 ATOM 2579 N N . VAL A 1 331 ? 55.613 124.924 14.589 1.00 42.54 ? 331 VAL A N 1 ATOM 2580 C CA . VAL A 1 331 ? 54.766 126.002 15.117 1.00 43.13 ? 331 VAL A CA 1 ATOM 2581 C C . VAL A 1 331 ? 55.312 126.578 16.413 1.00 43.75 ? 331 VAL A C 1 ATOM 2582 O O . VAL A 1 331 ? 54.671 127.435 17.023 1.00 43.72 ? 331 VAL A O 1 ATOM 2583 C CB . VAL A 1 331 ? 53.294 125.574 15.291 1.00 43.57 ? 331 VAL A CB 1 ATOM 2584 C CG1 . VAL A 1 331 ? 52.699 125.237 13.934 1.00 42.71 ? 331 VAL A CG1 1 ATOM 2585 C CG2 . VAL A 1 331 ? 53.134 124.375 16.335 1.00 42.47 ? 331 VAL A CG2 1 ATOM 2586 N N . TYR A 1 332 ? 56.486 126.097 16.827 1.00 43.38 ? 332 TYR A N 1 ATOM 2587 C CA . TYR A 1 332 ? 57.157 126.611 18.006 1.00 44.17 ? 332 TYR A CA 1 ATOM 2588 C C . TYR A 1 332 ? 58.364 127.476 17.633 1.00 45.79 ? 332 TYR A C 1 ATOM 2589 O O . TYR A 1 332 ? 59.341 127.552 18.389 1.00 46.42 ? 332 TYR A O 1 ATOM 2590 C CB . TYR A 1 332 ? 57.585 125.471 18.946 1.00 43.28 ? 332 TYR A CB 1 ATOM 2591 C CG . TYR A 1 332 ? 56.447 124.805 19.661 1.00 42.32 ? 332 TYR A CG 1 ATOM 2592 C CD1 . TYR A 1 332 ? 55.722 123.773 19.058 1.00 40.95 ? 332 TYR A CD1 1 ATOM 2593 C CD2 . TYR A 1 332 ? 56.103 125.190 20.972 1.00 43.15 ? 332 TYR A CD2 1 ATOM 2594 C CE1 . TYR A 1 332 ? 54.643 123.163 19.723 1.00 40.40 ? 332 TYR A CE1 1 ATOM 2595 C CE2 . TYR A 1 332 ? 55.051 124.588 21.654 1.00 40.62 ? 332 TYR A CE2 1 ATOM 2596 C CZ . TYR A 1 332 ? 54.330 123.571 21.032 1.00 42.71 ? 332 TYR A CZ 1 ATOM 2597 O OH . TYR A 1 332 ? 53.290 122.977 21.708 1.00 39.72 ? 332 TYR A OH 1 ATOM 2598 N N . GLY A 1 333 ? 58.298 128.152 16.485 1.00 47.21 ? 333 GLY A N 1 ATOM 2599 C CA . GLY A 1 333 ? 59.339 129.113 16.153 1.00 48.99 ? 333 GLY A CA 1 ATOM 2600 C C . GLY A 1 333 ? 59.644 129.321 14.670 1.00 50.34 ? 333 GLY A C 1 ATOM 2601 O O . GLY A 1 333 ? 60.353 130.256 14.337 1.00 51.29 ? 333 GLY A O 1 ATOM 2602 N N . ALA A 1 334 ? 59.148 128.460 13.782 1.00 49.77 ? 334 ALA A N 1 ATOM 2603 C CA . ALA A 1 334 ? 59.421 128.624 12.354 1.00 49.95 ? 334 ALA A CA 1 ATOM 2604 C C . ALA A 1 334 ? 58.490 129.651 11.690 1.00 50.22 ? 334 ALA A C 1 ATOM 2605 O O . ALA A 1 334 ? 57.253 129.546 11.825 1.00 50.38 ? 334 ALA A O 1 ATOM 2606 C CB . ALA A 1 334 ? 59.350 127.263 11.623 1.00 49.75 ? 334 ALA A CB 1 ATOM 2607 N N . PRO A 1 335 ? 59.072 130.638 10.979 1.00 50.34 ? 335 PRO A N 1 ATOM 2608 C CA . PRO A 1 335 ? 58.287 131.702 10.322 1.00 49.50 ? 335 PRO A CA 1 ATOM 2609 C C . PRO A 1 335 ? 57.317 131.199 9.278 1.00 49.25 ? 335 PRO A C 1 ATOM 2610 O O . PRO A 1 335 ? 57.653 130.329 8.468 1.00 49.26 ? 335 PRO A O 1 ATOM 2611 C CB . PRO A 1 335 ? 59.358 132.608 9.683 1.00 49.63 ? 335 PRO A CB 1 ATOM 2612 C CG . PRO A 1 335 ? 60.584 132.357 10.519 1.00 50.57 ? 335 PRO A CG 1 ATOM 2613 C CD . PRO A 1 335 ? 60.527 130.859 10.815 1.00 50.06 ? 335 PRO A CD 1 ATOM 2614 N N . GLY A 1 336 ? 56.099 131.733 9.327 1.00 48.37 ? 336 GLY A N 1 ATOM 2615 C CA . GLY A 1 336 ? 55.075 131.418 8.364 1.00 47.83 ? 336 GLY A CA 1 ATOM 2616 C C . GLY A 1 336 ? 54.246 130.228 8.769 1.00 47.97 ? 336 GLY A C 1 ATOM 2617 O O . GLY A 1 336 ? 53.305 129.873 8.057 1.00 48.36 ? 336 GLY A O 1 ATOM 2618 N N . PHE A 1 337 ? 54.584 129.620 9.909 1.00 47.19 ? 337 PHE A N 1 ATOM 2619 C CA . PHE A 1 337 ? 53.873 128.427 10.382 1.00 47.06 ? 337 PHE A CA 1 ATOM 2620 C C . PHE A 1 337 ? 52.793 128.777 11.406 1.00 47.37 ? 337 PHE A C 1 ATOM 2621 O O . PHE A 1 337 ? 52.947 129.735 12.169 1.00 48.23 ? 337 PHE A O 1 ATOM 2622 C CB . PHE A 1 337 ? 54.846 127.355 10.938 1.00 45.58 ? 337 PHE A CB 1 ATOM 2623 C CG . PHE A 1 337 ? 55.583 126.614 9.857 1.00 45.25 ? 337 PHE A CG 1 ATOM 2624 C CD1 . PHE A 1 337 ? 56.793 127.093 9.362 1.00 41.16 ? 337 PHE A CD1 1 ATOM 2625 C CD2 . PHE A 1 337 ? 55.031 125.481 9.277 1.00 43.32 ? 337 PHE A CD2 1 ATOM 2626 C CE1 . PHE A 1 337 ? 57.448 126.422 8.318 1.00 43.54 ? 337 PHE A CE1 1 ATOM 2627 C CE2 . PHE A 1 337 ? 55.691 124.824 8.216 1.00 44.75 ? 337 PHE A CE2 1 ATOM 2628 C CZ . PHE A 1 337 ? 56.906 125.291 7.756 1.00 39.96 ? 337 PHE A CZ 1 ATOM 2629 N N . SER A 1 338 ? 51.714 128.006 11.427 1.00 46.94 ? 338 SER A N 1 ATOM 2630 C CA . SER A 1 338 ? 50.701 128.214 12.448 1.00 46.57 ? 338 SER A CA 1 ATOM 2631 C C . SER A 1 338 ? 49.790 127.029 12.508 1.00 45.16 ? 338 SER A C 1 ATOM 2632 O O . SER A 1 338 ? 49.427 126.478 11.478 1.00 44.31 ? 338 SER A O 1 ATOM 2633 C CB . SER A 1 338 ? 49.913 129.518 12.170 1.00 47.27 ? 338 SER A CB 1 ATOM 2634 O OG . SER A 1 338 ? 48.712 129.605 12.912 1.00 48.32 ? 338 SER A OG 1 ATOM 2635 N N . LYS A 1 339 ? 49.388 126.632 13.711 1.00 45.20 ? 339 LYS A N 1 ATOM 2636 C CA . LYS A 1 339 ? 48.422 125.532 13.799 1.00 45.33 ? 339 LYS A CA 1 ATOM 2637 C C . LYS A 1 339 ? 47.052 125.943 13.231 1.00 46.20 ? 339 LYS A C 1 ATOM 2638 O O . LYS A 1 339 ? 46.227 125.082 12.933 1.00 46.66 ? 339 LYS A O 1 ATOM 2639 C CB . LYS A 1 339 ? 48.276 125.005 15.226 1.00 45.53 ? 339 LYS A CB 1 ATOM 2640 C CG . LYS A 1 339 ? 47.551 125.964 16.161 1.00 43.21 ? 339 LYS A CG 1 ATOM 2641 C CD . LYS A 1 339 ? 47.279 125.311 17.513 1.00 44.75 ? 339 LYS A CD 1 ATOM 2642 C CE . LYS A 1 339 ? 46.235 126.113 18.321 1.00 42.27 ? 339 LYS A CE 1 ATOM 2643 N NZ . LYS A 1 339 ? 44.881 126.070 17.633 1.00 40.78 ? 339 LYS A NZ 1 ATOM 2644 N N . ASP A 1 340 ? 46.813 127.247 13.067 1.00 46.89 ? 340 ASP A N 1 ATOM 2645 C CA . ASP A 1 340 ? 45.482 127.735 12.634 1.00 47.77 ? 340 ASP A CA 1 ATOM 2646 C C . ASP A 1 340 ? 45.346 128.171 11.159 1.00 49.41 ? 340 ASP A C 1 ATOM 2647 O O . ASP A 1 340 ? 44.356 128.835 10.788 1.00 49.05 ? 340 ASP A O 1 ATOM 2648 C CB . ASP A 1 340 ? 45.045 128.887 13.527 1.00 47.70 ? 340 ASP A CB 1 ATOM 2649 C CG . ASP A 1 340 ? 44.929 128.471 14.961 1.00 45.83 ? 340 ASP A CG 1 ATOM 2650 O OD1 . ASP A 1 340 ? 45.639 129.047 15.803 1.00 44.08 ? 340 ASP A OD1 1 ATOM 2651 O OD2 . ASP A 1 340 ? 44.195 127.532 15.313 1.00 43.92 ? 340 ASP A OD2 1 ATOM 2652 N N . ASN A 1 341 ? 46.326 127.806 10.335 1.00 49.57 ? 341 ASN A N 1 ATOM 2653 C CA . ASN A 1 341 ? 46.235 127.977 8.872 1.00 50.83 ? 341 ASN A CA 1 ATOM 2654 C C . ASN A 1 341 ? 47.172 126.981 8.212 1.00 51.41 ? 341 ASN A C 1 ATOM 2655 O O . ASN A 1 341 ? 47.930 126.275 8.899 1.00 51.68 ? 341 ASN A O 1 ATOM 2656 C CB . ASN A 1 341 ? 46.557 129.411 8.416 1.00 50.00 ? 341 ASN A CB 1 ATOM 2657 C CG . ASN A 1 341 ? 48.002 129.793 8.647 1.00 50.66 ? 341 ASN A CG 1 ATOM 2658 O OD1 . ASN A 1 341 ? 48.905 128.947 8.591 1.00 49.36 ? 341 ASN A OD1 1 ATOM 2659 N ND2 . ASN A 1 341 ? 48.220 131.083 8.946 1.00 49.91 ? 341 ASN A ND2 1 ATOM 2660 N N . ASN A 1 342 ? 47.133 126.918 6.889 1.00 51.57 ? 342 ASN A N 1 ATOM 2661 C CA . ASN A 1 342 ? 47.731 125.778 6.227 1.00 51.50 ? 342 ASN A CA 1 ATOM 2662 C C . ASN A 1 342 ? 49.244 125.877 6.055 1.00 50.77 ? 342 ASN A C 1 ATOM 2663 O O . ASN A 1 342 ? 49.856 124.989 5.483 1.00 51.41 ? 342 ASN A O 1 ATOM 2664 C CB . ASN A 1 342 ? 46.991 125.472 4.933 1.00 52.21 ? 342 ASN A CB 1 ATOM 2665 C CG . ASN A 1 342 ? 47.172 126.549 3.891 1.00 53.85 ? 342 ASN A CG 1 ATOM 2666 O OD1 . ASN A 1 342 ? 47.661 127.661 4.173 1.00 53.23 ? 342 ASN A OD1 1 ATOM 2667 N ND2 . ASN A 1 342 ? 46.775 126.224 2.659 1.00 57.82 ? 342 ASN A ND2 1 ATOM 2668 N N . SER A 1 343 ? 49.814 126.960 6.570 1.00 50.07 ? 343 SER A N 1 ATOM 2669 C CA . SER A 1 343 ? 51.252 127.152 6.731 1.00 50.06 ? 343 SER A CA 1 ATOM 2670 C C . SER A 1 343 ? 52.085 127.043 5.429 1.00 50.05 ? 343 SER A C 1 ATOM 2671 O O . SER A 1 343 ? 53.262 126.664 5.466 1.00 49.12 ? 343 SER A O 1 ATOM 2672 C CB . SER A 1 343 ? 51.794 126.246 7.856 1.00 49.48 ? 343 SER A CB 1 ATOM 2673 O OG . SER A 1 343 ? 51.264 126.636 9.119 1.00 48.49 ? 343 SER A OG 1 ATOM 2674 N N . ILE A 1 344 ? 51.469 127.397 4.294 1.00 50.23 ? 344 ILE A N 1 ATOM 2675 C CA . ILE A 1 344 ? 52.196 127.527 3.006 1.00 50.26 ? 344 ILE A CA 1 ATOM 2676 C C . ILE A 1 344 ? 53.305 128.544 3.218 1.00 50.03 ? 344 ILE A C 1 ATOM 2677 O O . ILE A 1 344 ? 53.046 129.707 3.504 1.00 51.19 ? 344 ILE A O 1 ATOM 2678 C CB . ILE A 1 344 ? 51.232 127.934 1.813 1.00 51.21 ? 344 ILE A CB 1 ATOM 2679 C CG1 . ILE A 1 344 ? 50.032 126.973 1.692 1.00 50.77 ? 344 ILE A CG1 1 ATOM 2680 C CG2 . ILE A 1 344 ? 51.988 127.990 0.436 1.00 50.65 ? 344 ILE A CG2 1 ATOM 2681 C CD1 . ILE A 1 344 ? 50.424 125.492 1.413 1.00 52.21 ? 344 ILE A CD1 1 ATOM 2682 N N . ILE A 1 345 ? 54.550 128.103 3.184 1.00 49.25 ? 345 ILE A N 1 ATOM 2683 C CA . ILE A 1 345 ? 55.650 129.027 3.339 1.00 47.85 ? 345 ILE A CA 1 ATOM 2684 C C . ILE A 1 345 ? 56.371 129.155 2.010 1.00 49.00 ? 345 ILE A C 1 ATOM 2685 O O . ILE A 1 345 ? 56.205 128.303 1.111 1.00 48.11 ? 345 ILE A O 1 ATOM 2686 C CB . ILE A 1 345 ? 56.615 128.547 4.419 1.00 48.32 ? 345 ILE A CB 1 ATOM 2687 C CG1 . ILE A 1 345 ? 57.036 127.075 4.171 1.00 46.61 ? 345 ILE A CG1 1 ATOM 2688 C CG2 . ILE A 1 345 ? 55.987 128.741 5.801 1.00 47.67 ? 345 ILE A CG2 1 ATOM 2689 C CD1 . ILE A 1 345 ? 58.385 126.738 4.736 1.00 41.42 ? 345 ILE A CD1 1 ATOM 2690 N N . THR A 1 346 ? 57.174 130.208 1.887 1.00 49.41 ? 346 THR A N 1 ATOM 2691 C CA . THR A 1 346 ? 57.991 130.403 0.697 1.00 50.64 ? 346 THR A CA 1 ATOM 2692 C C . THR A 1 346 ? 59.402 129.841 0.902 1.00 51.05 ? 346 THR A C 1 ATOM 2693 O O . THR A 1 346 ? 59.811 129.497 2.033 1.00 50.30 ? 346 THR A O 1 ATOM 2694 C CB . THR A 1 346 ? 58.125 131.895 0.387 1.00 50.26 ? 346 THR A CB 1 ATOM 2695 O OG1 . THR A 1 346 ? 58.590 132.565 1.571 1.00 52.66 ? 346 THR A OG1 1 ATOM 2696 C CG2 . THR A 1 346 ? 56.774 132.504 0.085 1.00 50.99 ? 346 THR A CG2 1 ATOM 2697 N N . ARG A 1 347 ? 60.147 129.786 -0.197 1.00 51.39 ? 347 ARG A N 1 ATOM 2698 C CA . ARG A 1 347 ? 61.567 129.441 -0.161 1.00 52.88 ? 347 ARG A CA 1 ATOM 2699 C C . ARG A 1 347 ? 62.303 130.179 0.953 1.00 52.49 ? 347 ARG A C 1 ATOM 2700 O O . ARG A 1 347 ? 63.064 129.577 1.733 1.00 53.28 ? 347 ARG A O 1 ATOM 2701 C CB . ARG A 1 347 ? 62.217 129.701 -1.539 1.00 52.87 ? 347 ARG A CB 1 ATOM 2702 C CG . ARG A 1 347 ? 63.752 129.513 -1.587 1.00 54.52 ? 347 ARG A CG 1 ATOM 2703 C CD . ARG A 1 347 ? 64.308 129.575 -3.014 1.00 55.88 ? 347 ARG A CD 1 ATOM 2704 N NE . ARG A 1 347 ? 65.698 129.114 -3.162 1.00 59.36 ? 347 ARG A NE 1 ATOM 2705 C CZ . ARG A 1 347 ? 66.089 127.851 -3.418 1.00 60.22 ? 347 ARG A CZ 1 ATOM 2706 N NH1 . ARG A 1 347 ? 67.384 127.595 -3.556 1.00 63.32 ? 347 ARG A NH1 1 ATOM 2707 N NH2 . ARG A 1 347 ? 65.220 126.844 -3.527 1.00 59.83 ? 347 ARG A NH2 1 ATOM 2708 N N . LYS A 1 348 ? 62.046 131.478 1.050 1.00 52.81 ? 348 LYS A N 1 ATOM 2709 C CA . LYS A 1 348 ? 62.756 132.329 1.981 1.00 52.35 ? 348 LYS A CA 1 ATOM 2710 C C . LYS A 1 348 ? 62.377 132.039 3.421 1.00 51.42 ? 348 LYS A C 1 ATOM 2711 O O . LYS A 1 348 ? 63.225 132.118 4.297 1.00 51.75 ? 348 LYS A O 1 ATOM 2712 C CB . LYS A 1 348 ? 62.540 133.817 1.639 1.00 53.36 ? 348 LYS A CB 1 ATOM 2713 C CG . LYS A 1 348 ? 63.775 134.717 1.902 1.00 57.05 ? 348 LYS A CG 1 ATOM 2714 C CD . LYS A 1 348 ? 65.076 134.148 1.210 1.00 62.93 ? 348 LYS A CD 1 ATOM 2715 C CE . LYS A 1 348 ? 66.415 134.543 1.926 1.00 66.02 ? 348 LYS A CE 1 ATOM 2716 N NZ . LYS A 1 348 ? 66.652 133.940 3.316 1.00 66.04 ? 348 LYS A NZ 1 ATOM 2717 N N . GLU A 1 349 ? 61.110 131.720 3.670 1.00 50.63 ? 349 GLU A N 1 ATOM 2718 C CA . GLU A 1 349 ? 60.677 131.249 5.003 1.00 50.36 ? 349 GLU A CA 1 ATOM 2719 C C . GLU A 1 349 ? 61.336 129.902 5.358 1.00 49.15 ? 349 GLU A C 1 ATOM 2720 O O . GLU A 1 349 ? 61.860 129.710 6.482 1.00 48.17 ? 349 GLU A O 1 ATOM 2721 C CB . GLU A 1 349 ? 59.139 131.192 5.080 1.00 50.73 ? 349 GLU A CB 1 ATOM 2722 C CG . GLU A 1 349 ? 58.524 132.606 5.150 1.00 54.65 ? 349 GLU A CG 1 ATOM 2723 C CD . GLU A 1 349 ? 57.014 132.659 4.986 1.00 55.65 ? 349 GLU A CD 1 ATOM 2724 O OE1 . GLU A 1 349 ? 56.384 133.377 5.781 1.00 58.23 ? 349 GLU A OE1 1 ATOM 2725 O OE2 . GLU A 1 349 ? 56.455 132.015 4.075 1.00 57.14 ? 349 GLU A OE2 1 ATOM 2726 N N . PHE A 1 350 ? 61.344 128.991 4.382 1.00 48.03 ? 350 PHE A N 1 ATOM 2727 C CA . PHE A 1 350 ? 62.063 127.716 4.523 1.00 47.74 ? 350 PHE A CA 1 ATOM 2728 C C . PHE A 1 350 ? 63.501 127.960 4.988 1.00 47.49 ? 350 PHE A C 1 ATOM 2729 O O . PHE A 1 350 ? 63.949 127.410 6.015 1.00 46.97 ? 350 PHE A O 1 ATOM 2730 C CB . PHE A 1 350 ? 62.015 126.929 3.226 1.00 46.67 ? 350 PHE A CB 1 ATOM 2731 C CG . PHE A 1 350 ? 62.755 125.615 3.283 1.00 48.39 ? 350 PHE A CG 1 ATOM 2732 C CD1 . PHE A 1 350 ? 62.097 124.446 3.685 1.00 44.48 ? 350 PHE A CD1 1 ATOM 2733 C CD2 . PHE A 1 350 ? 64.126 125.538 2.919 1.00 45.92 ? 350 PHE A CD2 1 ATOM 2734 C CE1 . PHE A 1 350 ? 62.798 123.214 3.737 1.00 48.82 ? 350 PHE A CE1 1 ATOM 2735 C CE2 . PHE A 1 350 ? 64.819 124.303 2.970 1.00 48.72 ? 350 PHE A CE2 1 ATOM 2736 C CZ . PHE A 1 350 ? 64.160 123.143 3.369 1.00 45.30 ? 350 PHE A CZ 1 ATOM 2737 N N . GLN A 1 351 ? 64.200 128.841 4.265 1.00 47.81 ? 351 GLN A N 1 ATOM 2738 C CA . GLN A 1 351 ? 65.593 129.175 4.586 1.00 47.70 ? 351 GLN A CA 1 ATOM 2739 C C . GLN A 1 351 ? 65.754 129.734 6.002 1.00 47.41 ? 351 GLN A C 1 ATOM 2740 O O . GLN A 1 351 ? 66.713 129.389 6.726 1.00 45.60 ? 351 GLN A O 1 ATOM 2741 C CB . GLN A 1 351 ? 66.168 130.125 3.530 1.00 48.15 ? 351 GLN A CB 1 ATOM 2742 C CG . GLN A 1 351 ? 66.405 129.444 2.141 1.00 51.20 ? 351 GLN A CG 1 ATOM 2743 C CD . GLN A 1 351 ? 66.844 130.425 1.036 1.00 54.36 ? 351 GLN A CD 1 ATOM 2744 O OE1 . GLN A 1 351 ? 66.188 131.437 0.802 1.00 56.44 ? 351 GLN A OE1 1 ATOM 2745 N NE2 . GLN A 1 351 ? 67.923 130.097 0.339 1.00 56.13 ? 351 GLN A NE2 1 ATOM 2746 N N . GLU A 1 352 ? 64.796 130.589 6.390 1.00 47.72 ? 352 GLU A N 1 ATOM 2747 C CA . GLU A 1 352 ? 64.752 131.166 7.751 1.00 47.77 ? 352 GLU A CA 1 ATOM 2748 C C . GLU A 1 352 ? 64.492 130.070 8.766 1.00 46.12 ? 352 GLU A C 1 ATOM 2749 O O . GLU A 1 352 ? 65.107 130.047 9.830 1.00 46.60 ? 352 GLU A O 1 ATOM 2750 C CB . GLU A 1 352 ? 63.664 132.272 7.880 1.00 49.08 ? 352 GLU A CB 1 ATOM 2751 C CG . GLU A 1 352 ? 63.937 133.581 7.129 1.00 52.81 ? 352 GLU A CG 1 ATOM 2752 C CD . GLU A 1 352 ? 65.340 134.160 7.362 1.00 57.96 ? 352 GLU A CD 1 ATOM 2753 O OE1 . GLU A 1 352 ? 65.806 134.227 8.528 1.00 59.41 ? 352 GLU A OE1 1 ATOM 2754 O OE2 . GLU A 1 352 ? 65.991 134.558 6.362 1.00 62.58 ? 352 GLU A OE2 1 ATOM 2755 N N . GLY A 1 353 ? 63.594 129.161 8.422 1.00 45.01 ? 353 GLY A N 1 ATOM 2756 C CA . GLY A 1 353 ? 63.291 127.998 9.275 1.00 45.34 ? 353 GLY A CA 1 ATOM 2757 C C . GLY A 1 353 ? 64.501 127.136 9.562 1.00 44.45 ? 353 GLY A C 1 ATOM 2758 O O . GLY A 1 353 ? 64.667 126.677 10.681 1.00 44.38 ? 353 GLY A O 1 ATOM 2759 N N . LEU A 1 354 ? 65.372 126.948 8.560 1.00 44.45 ? 354 LEU A N 1 ATOM 2760 C CA . LEU A 1 354 ? 66.621 126.184 8.766 1.00 43.93 ? 354 LEU A CA 1 ATOM 2761 C C . LEU A 1 354 ? 67.483 126.895 9.750 1.00 44.00 ? 354 LEU A C 1 ATOM 2762 O O . LEU A 1 354 ? 68.196 126.284 10.558 1.00 43.50 ? 354 LEU A O 1 ATOM 2763 C CB . LEU A 1 354 ? 67.427 125.980 7.475 1.00 42.98 ? 354 LEU A CB 1 ATOM 2764 C CG . LEU A 1 354 ? 66.956 124.982 6.423 1.00 43.61 ? 354 LEU A CG 1 ATOM 2765 C CD1 . LEU A 1 354 ? 68.064 124.736 5.394 1.00 41.96 ? 354 LEU A CD1 1 ATOM 2766 C CD2 . LEU A 1 354 ? 66.504 123.662 7.067 1.00 42.06 ? 354 LEU A CD2 1 ATOM 2767 N N . LYS A 1 355 ? 67.429 128.212 9.677 1.00 45.30 ? 355 LYS A N 1 ATOM 2768 C CA . LYS A 1 355 ? 68.202 129.005 10.595 1.00 46.51 ? 355 LYS A CA 1 ATOM 2769 C C . LYS A 1 355 ? 67.666 128.802 12.024 1.00 46.14 ? 355 LYS A C 1 ATOM 2770 O O . LYS A 1 355 ? 68.461 128.674 12.947 1.00 47.64 ? 355 LYS A O 1 ATOM 2771 C CB . LYS A 1 355 ? 68.212 130.466 10.136 1.00 47.02 ? 355 LYS A CB 1 ATOM 2772 C CG . LYS A 1 355 ? 69.406 131.213 10.630 1.00 51.41 ? 355 LYS A CG 1 ATOM 2773 C CD . LYS A 1 355 ? 69.370 132.711 10.333 1.00 56.97 ? 355 LYS A CD 1 ATOM 2774 C CE . LYS A 1 355 ? 69.453 133.018 8.827 1.00 62.19 ? 355 LYS A CE 1 ATOM 2775 N NZ . LYS A 1 355 ? 70.051 134.394 8.652 1.00 66.33 ? 355 LYS A NZ 1 ATOM 2776 N N . ILE A 1 356 ? 66.338 128.731 12.198 1.00 46.86 ? 356 ILE A N 1 ATOM 2777 C CA . ILE A 1 356 ? 65.712 128.420 13.515 1.00 47.32 ? 356 ILE A CA 1 ATOM 2778 C C . ILE A 1 356 ? 66.196 127.052 14.013 1.00 47.34 ? 356 ILE A C 1 ATOM 2779 O O . ILE A 1 356 ? 66.679 126.939 15.122 1.00 47.50 ? 356 ILE A O 1 ATOM 2780 C CB . ILE A 1 356 ? 64.130 128.414 13.484 1.00 47.14 ? 356 ILE A CB 1 ATOM 2781 C CG1 . ILE A 1 356 ? 63.480 129.773 13.078 1.00 47.82 ? 356 ILE A CG1 1 ATOM 2782 C CG2 . ILE A 1 356 ? 63.562 127.903 14.830 1.00 48.34 ? 356 ILE A CG2 1 ATOM 2783 C CD1 . ILE A 1 356 ? 63.991 131.025 13.749 1.00 46.92 ? 356 ILE A CD1 1 ATOM 2784 N N . PHE A 1 357 ? 66.108 126.029 13.155 1.00 47.41 ? 357 PHE A N 1 ATOM 2785 C CA . PHE A 1 357 ? 66.454 124.659 13.558 1.00 46.08 ? 357 PHE A CA 1 ATOM 2786 C C . PHE A 1 357 ? 67.935 124.293 13.549 1.00 46.59 ? 357 PHE A C 1 ATOM 2787 O O . PHE A 1 357 ? 68.321 123.335 14.196 1.00 46.54 ? 357 PHE A O 1 ATOM 2788 C CB . PHE A 1 357 ? 65.621 123.667 12.743 1.00 46.13 ? 357 PHE A CB 1 ATOM 2789 C CG . PHE A 1 357 ? 64.177 123.649 13.149 1.00 44.40 ? 357 PHE A CG 1 ATOM 2790 C CD1 . PHE A 1 357 ? 63.779 122.971 14.298 1.00 44.18 ? 357 PHE A CD1 1 ATOM 2791 C CD2 . PHE A 1 357 ? 63.221 124.349 12.411 1.00 45.32 ? 357 PHE A CD2 1 ATOM 2792 C CE1 . PHE A 1 357 ? 62.451 122.984 14.710 1.00 42.91 ? 357 PHE A CE1 1 ATOM 2793 C CE2 . PHE A 1 357 ? 61.868 124.365 12.805 1.00 46.15 ? 357 PHE A CE2 1 ATOM 2794 C CZ . PHE A 1 357 ? 61.488 123.673 13.953 1.00 43.68 ? 357 PHE A CZ 1 ATOM 2795 N N . PHE A 1 358 ? 68.766 125.059 12.841 1.00 47.35 ? 358 PHE A N 1 ATOM 2796 C CA . PHE A 1 358 ? 70.204 124.739 12.713 1.00 47.95 ? 358 PHE A CA 1 ATOM 2797 C C . PHE A 1 358 ? 71.066 125.981 12.992 1.00 49.70 ? 358 PHE A C 1 ATOM 2798 O O . PHE A 1 358 ? 71.861 126.413 12.141 1.00 49.91 ? 358 PHE A O 1 ATOM 2799 C CB . PHE A 1 358 ? 70.486 124.159 11.321 1.00 46.49 ? 358 PHE A CB 1 ATOM 2800 C CG . PHE A 1 358 ? 69.808 122.846 11.071 1.00 44.59 ? 358 PHE A CG 1 ATOM 2801 C CD1 . PHE A 1 358 ? 68.541 122.801 10.489 1.00 40.27 ? 358 PHE A CD1 1 ATOM 2802 C CD2 . PHE A 1 358 ? 70.413 121.640 11.465 1.00 39.61 ? 358 PHE A CD2 1 ATOM 2803 C CE1 . PHE A 1 358 ? 67.910 121.568 10.259 1.00 38.89 ? 358 PHE A CE1 1 ATOM 2804 C CE2 . PHE A 1 358 ? 69.776 120.432 11.232 1.00 37.45 ? 358 PHE A CE2 1 ATOM 2805 C CZ . PHE A 1 358 ? 68.531 120.400 10.636 1.00 36.65 ? 358 PHE A CZ 1 ATOM 2806 N N . PRO A 1 359 ? 70.886 126.560 14.185 1.00 51.41 ? 359 PRO A N 1 ATOM 2807 C CA . PRO A 1 359 ? 71.371 127.899 14.472 1.00 52.45 ? 359 PRO A CA 1 ATOM 2808 C C . PRO A 1 359 ? 72.883 128.074 14.412 1.00 52.96 ? 359 PRO A C 1 ATOM 2809 O O . PRO A 1 359 ? 73.348 129.150 13.992 1.00 53.93 ? 359 PRO A O 1 ATOM 2810 C CB . PRO A 1 359 ? 70.849 128.156 15.900 1.00 53.11 ? 359 PRO A CB 1 ATOM 2811 C CG . PRO A 1 359 ? 70.683 126.780 16.498 1.00 51.78 ? 359 PRO A CG 1 ATOM 2812 C CD . PRO A 1 359 ? 70.175 125.991 15.351 1.00 51.27 ? 359 PRO A CD 1 ATOM 2813 N N . GLY A 1 360 ? 73.641 127.069 14.840 1.00 52.54 ? 360 GLY A N 1 ATOM 2814 C CA . GLY A 1 360 ? 75.108 127.197 14.863 1.00 53.28 ? 360 GLY A CA 1 ATOM 2815 C C . GLY A 1 360 ? 75.771 126.456 13.698 1.00 53.64 ? 360 GLY A C 1 ATOM 2816 O O . GLY A 1 360 ? 76.937 126.032 13.795 1.00 54.46 ? 360 GLY A O 1 ATOM 2817 N N . VAL A 1 361 ? 75.011 126.278 12.611 1.00 52.60 ? 361 VAL A N 1 ATOM 2818 C CA . VAL A 1 361 ? 75.425 125.460 11.473 1.00 50.40 ? 361 VAL A CA 1 ATOM 2819 C C . VAL A 1 361 ? 75.890 126.410 10.379 1.00 49.81 ? 361 VAL A C 1 ATOM 2820 O O . VAL A 1 361 ? 75.244 127.439 10.103 1.00 49.33 ? 361 VAL A O 1 ATOM 2821 C CB . VAL A 1 361 ? 74.288 124.460 10.995 1.00 50.19 ? 361 VAL A CB 1 ATOM 2822 C CG1 . VAL A 1 361 ? 74.567 123.868 9.618 1.00 48.71 ? 361 VAL A CG1 1 ATOM 2823 C CG2 . VAL A 1 361 ? 74.087 123.328 12.020 1.00 47.35 ? 361 VAL A CG2 1 ATOM 2824 N N . SER A 1 362 ? 77.028 126.058 9.789 1.00 48.93 ? 362 SER A N 1 ATOM 2825 C CA . SER A 1 362 ? 77.637 126.823 8.722 1.00 48.56 ? 362 SER A CA 1 ATOM 2826 C C . SER A 1 362 ? 76.628 127.128 7.623 1.00 47.94 ? 362 SER A C 1 ATOM 2827 O O . SER A 1 362 ? 75.651 126.390 7.408 1.00 48.22 ? 362 SER A O 1 ATOM 2828 C CB . SER A 1 362 ? 78.839 126.046 8.160 1.00 48.59 ? 362 SER A CB 1 ATOM 2829 O OG . SER A 1 362 ? 78.447 125.046 7.229 1.00 47.93 ? 362 SER A OG 1 ATOM 2830 N N A GLU A 1 363 ? 76.845 128.212 6.897 0.50 47.64 ? 363 GLU A N 1 ATOM 2831 N N B GLU A 1 363 ? 76.866 128.242 6.953 0.50 47.73 ? 363 GLU A N 1 ATOM 2832 C CA A GLU A 1 363 ? 75.961 128.510 5.775 0.50 47.15 ? 363 GLU A CA 1 ATOM 2833 C CA B GLU A 1 363 ? 76.138 128.620 5.756 0.50 47.41 ? 363 GLU A CA 1 ATOM 2834 C C A GLU A 1 363 ? 76.002 127.402 4.706 0.50 46.35 ? 363 GLU A C 1 ATOM 2835 C C B GLU A 1 363 ? 76.037 127.443 4.760 0.50 46.50 ? 363 GLU A C 1 ATOM 2836 O O A GLU A 1 363 ? 74.991 127.124 4.038 0.50 46.43 ? 363 GLU A O 1 ATOM 2837 O O B GLU A 1 363 ? 74.965 127.157 4.205 0.50 46.71 ? 363 GLU A O 1 ATOM 2838 C CB A GLU A 1 363 ? 76.275 129.891 5.187 0.50 47.29 ? 363 GLU A CB 1 ATOM 2839 C CB B GLU A 1 363 ? 76.858 129.820 5.129 0.50 47.51 ? 363 GLU A CB 1 ATOM 2840 C CG A GLU A 1 363 ? 75.057 130.810 5.135 0.50 48.18 ? 363 GLU A CG 1 ATOM 2841 C CG B GLU A 1 363 ? 75.950 130.875 4.530 0.50 49.17 ? 363 GLU A CG 1 ATOM 2842 C CD A GLU A 1 363 ? 74.429 131.069 6.497 0.50 47.69 ? 363 GLU A CD 1 ATOM 2843 C CD B GLU A 1 363 ? 75.356 130.449 3.204 0.50 50.22 ? 363 GLU A CD 1 ATOM 2844 O OE1 A GLU A 1 363 ? 73.212 131.315 6.525 0.50 48.25 ? 363 GLU A OE1 1 ATOM 2845 O OE1 B GLU A 1 363 ? 74.248 130.941 2.845 0.50 48.35 ? 363 GLU A OE1 1 ATOM 2846 O OE2 A GLU A 1 363 ? 75.133 131.019 7.539 0.50 47.94 ? 363 GLU A OE2 1 ATOM 2847 O OE2 B GLU A 1 363 ? 76.011 129.619 2.529 0.50 51.25 ? 363 GLU A OE2 1 ATOM 2848 N N . PHE A 1 364 ? 77.160 126.764 4.551 1.00 45.30 ? 364 PHE A N 1 ATOM 2849 C CA . PHE A 1 364 ? 77.256 125.642 3.608 1.00 43.79 ? 364 PHE A CA 1 ATOM 2850 C C . PHE A 1 364 ? 76.403 124.445 4.108 1.00 42.51 ? 364 PHE A C 1 ATOM 2851 O O . PHE A 1 364 ? 75.706 123.804 3.327 1.00 42.35 ? 364 PHE A O 1 ATOM 2852 C CB . PHE A 1 364 ? 78.731 125.268 3.365 1.00 43.29 ? 364 PHE A CB 1 ATOM 2853 C CG . PHE A 1 364 ? 78.920 123.949 2.678 1.00 43.56 ? 364 PHE A CG 1 ATOM 2854 C CD1 . PHE A 1 364 ? 79.338 122.837 3.394 1.00 42.18 ? 364 PHE A CD1 1 ATOM 2855 C CD2 . PHE A 1 364 ? 78.662 123.816 1.328 1.00 41.69 ? 364 PHE A CD2 1 ATOM 2856 C CE1 . PHE A 1 364 ? 79.507 121.621 2.768 1.00 41.69 ? 364 PHE A CE1 1 ATOM 2857 C CE2 . PHE A 1 364 ? 78.820 122.611 0.715 1.00 44.46 ? 364 PHE A CE2 1 ATOM 2858 C CZ . PHE A 1 364 ? 79.246 121.508 1.439 1.00 40.95 ? 364 PHE A CZ 1 ATOM 2859 N N . GLY A 1 365 ? 76.426 124.200 5.415 1.00 42.18 ? 365 GLY A N 1 ATOM 2860 C CA . GLY A 1 365 ? 75.593 123.182 6.054 1.00 41.16 ? 365 GLY A CA 1 ATOM 2861 C C . GLY A 1 365 ? 74.123 123.370 5.730 1.00 41.42 ? 365 GLY A C 1 ATOM 2862 O O . GLY A 1 365 ? 73.429 122.432 5.300 1.00 41.22 ? 365 GLY A O 1 ATOM 2863 N N . LYS A 1 366 ? 73.657 124.610 5.853 1.00 41.25 ? 366 LYS A N 1 ATOM 2864 C CA . LYS A 1 366 ? 72.260 124.911 5.574 1.00 41.24 ? 366 LYS A CA 1 ATOM 2865 C C . LYS A 1 366 ? 71.881 124.836 4.111 1.00 40.65 ? 366 LYS A C 1 ATOM 2866 O O . LYS A 1 366 ? 70.779 124.353 3.789 1.00 40.66 ? 366 LYS A O 1 ATOM 2867 C CB . LYS A 1 366 ? 71.826 126.244 6.194 1.00 41.12 ? 366 LYS A CB 1 ATOM 2868 C CG . LYS A 1 366 ? 71.986 126.295 7.725 1.00 44.57 ? 366 LYS A CG 1 ATOM 2869 C CD . LYS A 1 366 ? 71.456 127.616 8.267 1.00 49.34 ? 366 LYS A CD 1 ATOM 2870 C CE . LYS A 1 366 ? 72.611 128.586 8.547 1.00 54.22 ? 366 LYS A CE 1 ATOM 2871 N NZ . LYS A 1 366 ? 72.761 128.756 10.030 1.00 59.05 ? 366 LYS A NZ 1 ATOM 2872 N N A GLU A 1 367 ? 72.737 125.308 3.207 0.50 40.60 ? 367 GLU A N 1 ATOM 2873 N N B GLU A 1 367 ? 72.776 125.306 3.235 0.50 40.36 ? 367 GLU A N 1 ATOM 2874 C CA A GLU A 1 367 ? 72.400 125.200 1.775 0.50 40.26 ? 367 GLU A CA 1 ATOM 2875 C CA B GLU A 1 367 ? 72.582 125.216 1.774 0.50 39.91 ? 367 GLU A CA 1 ATOM 2876 C C A GLU A 1 367 ? 72.359 123.710 1.346 0.50 39.50 ? 367 GLU A C 1 ATOM 2877 C C B GLU A 1 367 ? 72.416 123.749 1.338 0.50 39.26 ? 367 GLU A C 1 ATOM 2878 O O A GLU A 1 367 ? 71.496 123.290 0.538 0.50 39.23 ? 367 GLU A O 1 ATOM 2879 O O B GLU A 1 367 ? 71.562 123.394 0.494 0.50 39.07 ? 367 GLU A O 1 ATOM 2880 C CB A GLU A 1 367 ? 73.349 126.059 0.917 0.50 40.78 ? 367 GLU A CB 1 ATOM 2881 C CB B GLU A 1 367 ? 73.787 125.823 1.035 0.50 40.02 ? 367 GLU A CB 1 ATOM 2882 C CG A GLU A 1 367 ? 73.197 125.919 -0.596 0.50 42.55 ? 367 GLU A CG 1 ATOM 2883 C CG B GLU A 1 367 ? 73.887 127.344 1.030 0.50 41.07 ? 367 GLU A CG 1 ATOM 2884 C CD A GLU A 1 367 ? 72.073 126.745 -1.221 0.50 47.72 ? 367 GLU A CD 1 ATOM 2885 C CD B GLU A 1 367 ? 74.858 127.864 -0.033 0.50 42.18 ? 367 GLU A CD 1 ATOM 2886 O OE1 A GLU A 1 367 ? 71.316 126.170 -2.041 0.50 51.13 ? 367 GLU A OE1 1 ATOM 2887 O OE1 B GLU A 1 367 ? 76.074 127.576 0.036 0.50 39.75 ? 367 GLU A OE1 1 ATOM 2888 O OE2 A GLU A 1 367 ? 71.951 127.961 -0.935 0.50 47.21 ? 367 GLU A OE2 1 ATOM 2889 O OE2 B GLU A 1 367 ? 74.395 128.558 -0.966 0.50 45.63 ? 367 GLU A OE2 1 ATOM 2890 N N . SER A 1 368 ? 73.240 122.899 1.931 1.00 39.05 ? 368 SER A N 1 ATOM 2891 C CA . SER A 1 368 ? 73.250 121.451 1.629 1.00 38.68 ? 368 SER A CA 1 ATOM 2892 C C . SER A 1 368 ? 71.919 120.751 2.019 1.00 38.22 ? 368 SER A C 1 ATOM 2893 O O . SER A 1 368 ? 71.417 119.864 1.305 1.00 37.93 ? 368 SER A O 1 ATOM 2894 C CB . SER A 1 368 ? 74.475 120.809 2.269 1.00 38.21 ? 368 SER A CB 1 ATOM 2895 O OG . SER A 1 368 ? 74.206 120.402 3.589 1.00 41.20 ? 368 SER A OG 1 ATOM 2896 N N . ILE A 1 369 ? 71.313 121.200 3.120 1.00 38.48 ? 369 ILE A N 1 ATOM 2897 C CA . ILE A 1 369 ? 69.978 120.701 3.498 1.00 37.98 ? 369 ILE A CA 1 ATOM 2898 C C . ILE A 1 369 ? 69.013 121.152 2.437 1.00 38.09 ? 369 ILE A C 1 ATOM 2899 O O . ILE A 1 369 ? 68.272 120.355 1.879 1.00 38.15 ? 369 ILE A O 1 ATOM 2900 C CB . ILE A 1 369 ? 69.509 121.218 4.883 1.00 37.61 ? 369 ILE A CB 1 ATOM 2901 C CG1 . ILE A 1 369 ? 70.465 120.792 5.989 1.00 37.17 ? 369 ILE A CG1 1 ATOM 2902 C CG2 . ILE A 1 369 ? 68.132 120.675 5.179 1.00 37.51 ? 369 ILE A CG2 1 ATOM 2903 C CD1 . ILE A 1 369 ? 70.115 121.423 7.329 1.00 40.19 ? 369 ILE A CD1 1 ATOM 2904 N N . LEU A 1 370 ? 69.019 122.454 2.173 1.00 39.26 ? 370 LEU A N 1 ATOM 2905 C CA . LEU A 1 370 ? 68.188 123.004 1.142 1.00 40.17 ? 370 LEU A CA 1 ATOM 2906 C C . LEU A 1 370 ? 68.370 122.248 -0.163 1.00 40.36 ? 370 LEU A C 1 ATOM 2907 O O . LEU A 1 370 ? 67.393 121.872 -0.792 1.00 40.47 ? 370 LEU A O 1 ATOM 2908 C CB . LEU A 1 370 ? 68.460 124.508 0.959 1.00 40.77 ? 370 LEU A CB 1 ATOM 2909 C CG . LEU A 1 370 ? 67.504 125.061 -0.099 1.00 42.33 ? 370 LEU A CG 1 ATOM 2910 C CD1 . LEU A 1 370 ? 66.976 126.373 0.239 1.00 44.53 ? 370 LEU A CD1 1 ATOM 2911 C CD2 . LEU A 1 370 ? 68.209 125.089 -1.457 1.00 42.83 ? 370 LEU A CD2 1 ATOM 2912 N N . PHE A 1 371 ? 69.614 122.043 -0.585 1.00 41.47 ? 371 PHE A N 1 ATOM 2913 C CA . PHE A 1 371 ? 69.863 121.280 -1.836 1.00 42.60 ? 371 PHE A CA 1 ATOM 2914 C C . PHE A 1 371 ? 69.217 119.880 -1.822 1.00 41.88 ? 371 PHE A C 1 ATOM 2915 O O . PHE A 1 371 ? 68.520 119.493 -2.779 1.00 40.62 ? 371 PHE A O 1 ATOM 2916 C CB . PHE A 1 371 ? 71.374 121.151 -2.085 1.00 43.50 ? 371 PHE A CB 1 ATOM 2917 C CG . PHE A 1 371 ? 71.708 120.389 -3.315 1.00 48.22 ? 371 PHE A CG 1 ATOM 2918 C CD1 . PHE A 1 371 ? 72.114 119.046 -3.231 1.00 51.13 ? 371 PHE A CD1 1 ATOM 2919 C CD2 . PHE A 1 371 ? 71.620 121.004 -4.580 1.00 52.55 ? 371 PHE A CD2 1 ATOM 2920 C CE1 . PHE A 1 371 ? 72.416 118.312 -4.399 1.00 52.60 ? 371 PHE A CE1 1 ATOM 2921 C CE2 . PHE A 1 371 ? 71.911 120.266 -5.771 1.00 55.13 ? 371 PHE A CE2 1 ATOM 2922 C CZ . PHE A 1 371 ? 72.324 118.935 -5.684 1.00 52.05 ? 371 PHE A CZ 1 ATOM 2923 N N A HIS A 1 372 ? 69.454 119.121 -0.746 0.50 41.45 ? 372 HIS A N 1 ATOM 2924 N N B HIS A 1 372 ? 69.441 119.138 -0.743 0.50 41.91 ? 372 HIS A N 1 ATOM 2925 C CA A HIS A 1 372 ? 68.919 117.749 -0.655 0.50 42.00 ? 372 HIS A CA 1 ATOM 2926 C CA B HIS A 1 372 ? 68.963 117.761 -0.699 0.50 42.81 ? 372 HIS A CA 1 ATOM 2927 C C A HIS A 1 372 ? 67.390 117.744 -0.664 0.50 43.06 ? 372 HIS A C 1 ATOM 2928 C C B HIS A 1 372 ? 67.443 117.634 -0.456 0.50 43.54 ? 372 HIS A C 1 ATOM 2929 O O A HIS A 1 372 ? 66.756 116.934 -1.358 0.50 42.49 ? 372 HIS A O 1 ATOM 2930 O O B HIS A 1 372 ? 66.852 116.616 -0.815 0.50 43.14 ? 372 HIS A O 1 ATOM 2931 C CB A HIS A 1 372 ? 69.438 116.997 0.583 0.50 41.33 ? 372 HIS A CB 1 ATOM 2932 C CB B HIS A 1 372 ? 69.821 116.913 0.252 0.50 42.91 ? 372 HIS A CB 1 ATOM 2933 C CG A HIS A 1 372 ? 69.167 115.525 0.537 0.50 40.49 ? 372 HIS A CG 1 ATOM 2934 C CG B HIS A 1 372 ? 71.209 116.644 -0.271 0.50 42.96 ? 372 HIS A CG 1 ATOM 2935 N ND1 A HIS A 1 372 ? 69.975 114.637 -0.144 0.50 38.02 ? 372 HIS A ND1 1 ATOM 2936 N ND1 B HIS A 1 372 ? 72.270 117.501 -0.055 0.50 43.32 ? 372 HIS A ND1 1 ATOM 2937 C CD2 A HIS A 1 372 ? 68.159 114.789 1.061 0.50 39.78 ? 372 HIS A CD2 1 ATOM 2938 C CD2 B HIS A 1 372 ? 71.703 115.619 -1.007 0.50 42.36 ? 372 HIS A CD2 1 ATOM 2939 C CE1 A HIS A 1 372 ? 69.471 113.422 -0.041 0.50 38.18 ? 372 HIS A CE1 1 ATOM 2940 C CE1 B HIS A 1 372 ? 73.358 117.005 -0.615 0.50 42.56 ? 372 HIS A CE1 1 ATOM 2941 N NE2 A HIS A 1 372 ? 68.370 113.488 0.687 0.50 39.37 ? 372 HIS A NE2 1 ATOM 2942 N NE2 B HIS A 1 372 ? 73.041 115.868 -1.206 0.50 41.30 ? 372 HIS A NE2 1 ATOM 2943 N N . TYR A 1 373 ? 66.807 118.688 0.072 1.00 43.92 ? 373 TYR A N 1 ATOM 2944 C CA . TYR A 1 373 ? 65.355 118.677 0.310 1.00 46.64 ? 373 TYR A CA 1 ATOM 2945 C C . TYR A 1 373 ? 64.459 119.506 -0.617 1.00 49.27 ? 373 TYR A C 1 ATOM 2946 O O . TYR A 1 373 ? 63.241 119.537 -0.401 1.00 49.49 ? 373 TYR A O 1 ATOM 2947 C CB . TYR A 1 373 ? 65.067 119.020 1.787 1.00 45.87 ? 373 TYR A CB 1 ATOM 2948 C CG . TYR A 1 373 ? 65.234 117.828 2.712 1.00 43.93 ? 373 TYR A CG 1 ATOM 2949 C CD1 . TYR A 1 373 ? 64.129 116.991 3.024 1.00 43.25 ? 373 TYR A CD1 1 ATOM 2950 C CD2 . TYR A 1 373 ? 66.479 117.539 3.289 1.00 39.75 ? 373 TYR A CD2 1 ATOM 2951 C CE1 . TYR A 1 373 ? 64.281 115.874 3.898 1.00 41.81 ? 373 TYR A CE1 1 ATOM 2952 C CE2 . TYR A 1 373 ? 66.639 116.459 4.157 1.00 41.22 ? 373 TYR A CE2 1 ATOM 2953 C CZ . TYR A 1 373 ? 65.532 115.623 4.459 1.00 40.82 ? 373 TYR A CZ 1 ATOM 2954 O OH . TYR A 1 373 ? 65.711 114.539 5.276 1.00 39.12 ? 373 TYR A OH 1 ATOM 2955 N N . THR A 1 374 ? 65.026 120.177 -1.632 1.00 52.47 ? 374 THR A N 1 ATOM 2956 C CA . THR A 1 374 ? 64.198 121.030 -2.516 1.00 56.45 ? 374 THR A CA 1 ATOM 2957 C C . THR A 1 374 ? 64.292 120.671 -3.989 1.00 58.98 ? 374 THR A C 1 ATOM 2958 O O . THR A 1 374 ? 64.068 121.525 -4.854 1.00 58.33 ? 374 THR A O 1 ATOM 2959 C CB . THR A 1 374 ? 64.534 122.541 -2.377 1.00 56.37 ? 374 THR A CB 1 ATOM 2960 O OG1 . THR A 1 374 ? 65.932 122.724 -2.632 1.00 58.92 ? 374 THR A OG1 1 ATOM 2961 C CG2 . THR A 1 374 ? 64.340 123.036 -0.953 1.00 56.52 ? 374 THR A CG2 1 ATOM 2962 N N . ASP A 1 375 ? 64.635 119.423 -4.276 1.00 62.59 ? 375 ASP A N 1 ATOM 2963 C CA . ASP A 1 375 ? 64.575 118.935 -5.648 1.00 66.01 ? 375 ASP A CA 1 ATOM 2964 C C . ASP A 1 375 ? 63.195 118.304 -5.918 1.00 67.43 ? 375 ASP A C 1 ATOM 2965 O O . ASP A 1 375 ? 62.973 117.110 -5.676 1.00 67.71 ? 375 ASP A O 1 ATOM 2966 C CB . ASP A 1 375 ? 65.714 117.966 -5.927 1.00 66.67 ? 375 ASP A CB 1 ATOM 2967 C CG . ASP A 1 375 ? 65.975 117.818 -7.403 1.00 69.54 ? 375 ASP A CG 1 ATOM 2968 O OD1 . ASP A 1 375 ? 66.901 118.500 -7.909 1.00 71.05 ? 375 ASP A OD1 1 ATOM 2969 O OD2 . ASP A 1 375 ? 65.267 117.079 -8.132 1.00 72.22 ? 375 ASP A OD2 1 ATOM 2970 N N . TRP A 1 376 ? 62.278 119.139 -6.408 1.00 69.08 ? 376 TRP A N 1 ATOM 2971 C CA . TRP A 1 376 ? 60.855 118.820 -6.483 1.00 70.72 ? 376 TRP A CA 1 ATOM 2972 C C . TRP A 1 376 ? 60.502 117.927 -7.685 1.00 72.17 ? 376 TRP A C 1 ATOM 2973 O O . TRP A 1 376 ? 61.070 118.093 -8.778 1.00 72.75 ? 376 TRP A O 1 ATOM 2974 C CB . TRP A 1 376 ? 60.028 120.102 -6.571 1.00 70.56 ? 376 TRP A CB 1 ATOM 2975 C CG . TRP A 1 376 ? 60.402 121.238 -5.630 1.00 70.17 ? 376 TRP A CG 1 ATOM 2976 C CD1 . TRP A 1 376 ? 60.747 122.512 -5.991 1.00 69.01 ? 376 TRP A CD1 1 ATOM 2977 C CD2 . TRP A 1 376 ? 60.420 121.214 -4.190 1.00 68.39 ? 376 TRP A CD2 1 ATOM 2978 N NE1 . TRP A 1 376 ? 60.991 123.273 -4.871 1.00 69.99 ? 376 TRP A NE1 1 ATOM 2979 C CE2 . TRP A 1 376 ? 60.793 122.506 -3.752 1.00 68.47 ? 376 TRP A CE2 1 ATOM 2980 C CE3 . TRP A 1 376 ? 60.172 120.229 -3.223 1.00 67.56 ? 376 TRP A CE3 1 ATOM 2981 C CZ2 . TRP A 1 376 ? 60.920 122.839 -2.395 1.00 68.41 ? 376 TRP A CZ2 1 ATOM 2982 C CZ3 . TRP A 1 376 ? 60.297 120.563 -1.871 1.00 66.67 ? 376 TRP A CZ3 1 ATOM 2983 C CH2 . TRP A 1 376 ? 60.668 121.855 -1.475 1.00 66.84 ? 376 TRP A CH2 1 ATOM 2984 N N . VAL A 1 377 ? 59.543 117.020 -7.469 1.00 73.41 ? 377 VAL A N 1 ATOM 2985 C CA . VAL A 1 377 ? 59.125 116.017 -8.454 1.00 74.80 ? 377 VAL A CA 1 ATOM 2986 C C . VAL A 1 377 ? 57.745 116.358 -9.031 1.00 75.28 ? 377 VAL A C 1 ATOM 2987 O O . VAL A 1 377 ? 57.497 117.494 -9.463 1.00 75.93 ? 377 VAL A O 1 ATOM 2988 C CB . VAL A 1 377 ? 59.096 114.568 -7.854 1.00 74.95 ? 377 VAL A CB 1 ATOM 2989 C CG1 . VAL A 1 377 ? 59.153 113.490 -8.984 1.00 75.57 ? 377 VAL A CG1 1 ATOM 2990 C CG2 . VAL A 1 377 ? 60.232 114.351 -6.832 1.00 75.76 ? 377 VAL A CG2 1 ATOM 2991 N N . GLN A 1 380 ? 56.379 124.623 -8.348 1.00 71.99 ? 380 GLN A N 1 ATOM 2992 C CA . GLN A 1 380 ? 55.393 123.546 -8.465 1.00 72.27 ? 380 GLN A CA 1 ATOM 2993 C C . GLN A 1 380 ? 54.227 123.684 -7.454 1.00 71.59 ? 380 GLN A C 1 ATOM 2994 O O . GLN A 1 380 ? 53.465 124.679 -7.460 1.00 71.74 ? 380 GLN A O 1 ATOM 2995 C CB . GLN A 1 380 ? 56.082 122.170 -8.276 1.00 72.87 ? 380 GLN A CB 1 ATOM 2996 C CG . GLN A 1 380 ? 56.162 121.274 -9.513 1.00 73.94 ? 380 GLN A CG 1 ATOM 2997 C CD . GLN A 1 380 ? 54.860 120.520 -9.780 1.00 74.10 ? 380 GLN A CD 1 ATOM 2998 O OE1 . GLN A 1 380 ? 54.750 119.328 -9.472 1.00 72.64 ? 380 GLN A OE1 1 ATOM 2999 N NE2 . GLN A 1 380 ? 53.871 121.216 -10.345 1.00 74.45 ? 380 GLN A NE2 1 ATOM 3000 N N . ARG A 1 381 ? 54.124 122.659 -6.599 1.00 70.32 ? 381 ARG A N 1 ATOM 3001 C CA . ARG A 1 381 ? 53.108 122.502 -5.550 1.00 68.34 ? 381 ARG A CA 1 ATOM 3002 C C . ARG A 1 381 ? 53.270 123.510 -4.417 1.00 66.23 ? 381 ARG A C 1 ATOM 3003 O O . ARG A 1 381 ? 54.378 123.692 -3.893 1.00 65.83 ? 381 ARG A O 1 ATOM 3004 C CB . ARG A 1 381 ? 53.214 121.096 -4.972 1.00 69.06 ? 381 ARG A CB 1 ATOM 3005 C CG . ARG A 1 381 ? 53.002 119.976 -5.989 1.00 70.56 ? 381 ARG A CG 1 ATOM 3006 C CD . ARG A 1 381 ? 53.066 118.577 -5.395 1.00 73.81 ? 381 ARG A CD 1 ATOM 3007 N NE . ARG A 1 381 ? 52.264 118.457 -4.174 1.00 76.96 ? 381 ARG A NE 1 ATOM 3008 C CZ . ARG A 1 381 ? 52.760 118.466 -2.930 1.00 78.46 ? 381 ARG A CZ 1 ATOM 3009 N NH1 . ARG A 1 381 ? 51.933 118.361 -1.895 1.00 77.87 ? 381 ARG A NH1 1 ATOM 3010 N NH2 . ARG A 1 381 ? 54.074 118.582 -2.716 1.00 77.41 ? 381 ARG A NH2 1 ATOM 3011 N N . PRO A 1 382 ? 52.172 124.153 -4.023 1.00 64.22 ? 382 PRO A N 1 ATOM 3012 C CA . PRO A 1 382 ? 52.234 125.214 -2.998 1.00 62.53 ? 382 PRO A CA 1 ATOM 3013 C C . PRO A 1 382 ? 52.854 124.758 -1.663 1.00 60.71 ? 382 PRO A C 1 ATOM 3014 O O . PRO A 1 382 ? 53.551 125.533 -1.017 1.00 59.52 ? 382 PRO A O 1 ATOM 3015 C CB . PRO A 1 382 ? 50.761 125.625 -2.807 1.00 62.76 ? 382 PRO A CB 1 ATOM 3016 C CG . PRO A 1 382 ? 50.027 125.087 -3.993 1.00 63.52 ? 382 PRO A CG 1 ATOM 3017 C CD . PRO A 1 382 ? 50.798 123.906 -4.504 1.00 63.82 ? 382 PRO A CD 1 ATOM 3018 N N . GLU A 1 383 ? 52.618 123.510 -1.263 1.00 59.28 ? 383 GLU A N 1 ATOM 3019 C CA . GLU A 1 383 ? 53.110 123.038 0.053 1.00 58.44 ? 383 GLU A CA 1 ATOM 3020 C C . GLU A 1 383 ? 54.488 122.351 0.049 1.00 57.14 ? 383 GLU A C 1 ATOM 3021 O O . GLU A 1 383 ? 54.903 121.746 1.065 1.00 56.01 ? 383 GLU A O 1 ATOM 3022 C CB . GLU A 1 383 ? 52.072 122.181 0.790 1.00 58.83 ? 383 GLU A CB 1 ATOM 3023 C CG . GLU A 1 383 ? 51.649 120.908 0.100 1.00 61.78 ? 383 GLU A CG 1 ATOM 3024 C CD . GLU A 1 383 ? 50.506 121.135 -0.867 1.00 67.99 ? 383 GLU A CD 1 ATOM 3025 O OE1 . GLU A 1 383 ? 49.427 120.556 -0.621 1.00 71.84 ? 383 GLU A OE1 1 ATOM 3026 O OE2 . GLU A 1 383 ? 50.676 121.883 -1.870 1.00 69.03 ? 383 GLU A OE2 1 ATOM 3027 N N . ASN A 1 384 ? 55.191 122.459 -1.086 1.00 55.13 ? 384 ASN A N 1 ATOM 3028 C CA . ASN A 1 384 ? 56.532 121.916 -1.220 1.00 52.89 ? 384 ASN A CA 1 ATOM 3029 C C . ASN A 1 384 ? 57.429 122.314 -0.043 1.00 51.14 ? 384 ASN A C 1 ATOM 3030 O O . ASN A 1 384 ? 57.975 121.445 0.653 1.00 50.26 ? 384 ASN A O 1 ATOM 3031 C CB . ASN A 1 384 ? 57.157 122.343 -2.552 1.00 53.38 ? 384 ASN A CB 1 ATOM 3032 C CG . ASN A 1 384 ? 56.762 121.441 -3.704 1.00 55.73 ? 384 ASN A CG 1 ATOM 3033 O OD1 . ASN A 1 384 ? 56.227 120.321 -3.518 1.00 57.90 ? 384 ASN A OD1 1 ATOM 3034 N ND2 . ASN A 1 384 ? 57.045 121.905 -4.918 1.00 59.16 ? 384 ASN A ND2 1 ATOM 3035 N N . TYR A 1 385 ? 57.562 123.617 0.184 1.00 49.21 ? 385 TYR A N 1 ATOM 3036 C CA . TYR A 1 385 ? 58.438 124.110 1.233 1.00 49.21 ? 385 TYR A CA 1 ATOM 3037 C C . TYR A 1 385 ? 57.996 123.743 2.674 1.00 47.32 ? 385 TYR A C 1 ATOM 3038 O O . TYR A 1 385 ? 58.826 123.371 3.499 1.00 46.05 ? 385 TYR A O 1 ATOM 3039 C CB . TYR A 1 385 ? 58.680 125.620 1.083 1.00 49.65 ? 385 TYR A CB 1 ATOM 3040 C CG . TYR A 1 385 ? 59.610 125.936 -0.070 1.00 52.62 ? 385 TYR A CG 1 ATOM 3041 C CD1 . TYR A 1 385 ? 60.984 125.710 0.038 1.00 52.65 ? 385 TYR A CD1 1 ATOM 3042 C CD2 . TYR A 1 385 ? 59.110 126.450 -1.281 1.00 55.24 ? 385 TYR A CD2 1 ATOM 3043 C CE1 . TYR A 1 385 ? 61.844 125.984 -1.022 1.00 54.88 ? 385 TYR A CE1 1 ATOM 3044 C CE2 . TYR A 1 385 ? 59.959 126.729 -2.341 1.00 55.03 ? 385 TYR A CE2 1 ATOM 3045 C CZ . TYR A 1 385 ? 61.328 126.501 -2.201 1.00 55.49 ? 385 TYR A CZ 1 ATOM 3046 O OH . TYR A 1 385 ? 62.178 126.775 -3.247 1.00 56.82 ? 385 TYR A OH 1 ATOM 3047 N N . ARG A 1 386 ? 56.695 123.858 2.936 1.00 45.64 ? 386 ARG A N 1 ATOM 3048 C CA . ARG A 1 386 ? 56.083 123.460 4.215 1.00 44.14 ? 386 ARG A CA 1 ATOM 3049 C C . ARG A 1 386 ? 56.380 121.972 4.531 1.00 43.17 ? 386 ARG A C 1 ATOM 3050 O O . ARG A 1 386 ? 56.767 121.617 5.644 1.00 41.74 ? 386 ARG A O 1 ATOM 3051 C CB . ARG A 1 386 ? 54.582 123.670 4.127 1.00 43.43 ? 386 ARG A CB 1 ATOM 3052 C CG . ARG A 1 386 ? 53.825 123.450 5.448 1.00 44.58 ? 386 ARG A CG 1 ATOM 3053 C CD . ARG A 1 386 ? 52.326 123.420 5.259 1.00 42.16 ? 386 ARG A CD 1 ATOM 3054 N NE . ARG A 1 386 ? 51.871 122.151 4.716 1.00 44.46 ? 386 ARG A NE 1 ATOM 3055 C CZ . ARG A 1 386 ? 50.722 121.958 4.049 1.00 45.41 ? 386 ARG A CZ 1 ATOM 3056 N NH1 . ARG A 1 386 ? 49.879 122.971 3.839 1.00 44.50 ? 386 ARG A NH1 1 ATOM 3057 N NH2 . ARG A 1 386 ? 50.419 120.737 3.597 1.00 44.43 ? 386 ARG A NH2 1 ATOM 3058 N N . GLU A 1 387 ? 56.195 121.130 3.532 1.00 41.87 ? 387 GLU A N 1 ATOM 3059 C CA . GLU A 1 387 ? 56.412 119.721 3.683 1.00 42.79 ? 387 GLU A CA 1 ATOM 3060 C C . GLU A 1 387 ? 57.893 119.403 3.872 1.00 41.30 ? 387 GLU A C 1 ATOM 3061 O O . GLU A 1 387 ? 58.227 118.548 4.688 1.00 40.00 ? 387 GLU A O 1 ATOM 3062 C CB . GLU A 1 387 ? 55.815 118.927 2.503 1.00 43.36 ? 387 GLU A CB 1 ATOM 3063 C CG . GLU A 1 387 ? 54.390 119.339 2.208 1.00 49.45 ? 387 GLU A CG 1 ATOM 3064 C CD . GLU A 1 387 ? 53.434 118.184 1.982 1.00 58.06 ? 387 GLU A CD 1 ATOM 3065 O OE1 . GLU A 1 387 ? 52.309 118.205 2.572 1.00 59.99 ? 387 GLU A OE1 1 ATOM 3066 O OE2 . GLU A 1 387 ? 53.798 117.268 1.208 1.00 61.06 ? 387 GLU A OE2 1 ATOM 3067 N N . ALA A 1 388 ? 58.763 120.104 3.138 1.00 39.54 ? 388 ALA A N 1 ATOM 3068 C CA . ALA A 1 388 ? 60.208 119.818 3.214 1.00 38.56 ? 388 ALA A CA 1 ATOM 3069 C C . ALA A 1 388 ? 60.779 120.140 4.590 1.00 37.32 ? 388 ALA A C 1 ATOM 3070 O O . ALA A 1 388 ? 61.653 119.424 5.052 1.00 36.40 ? 388 ALA A O 1 ATOM 3071 C CB . ALA A 1 388 ? 61.018 120.583 2.119 1.00 37.33 ? 388 ALA A CB 1 ATOM 3072 N N . LEU A 1 389 ? 60.328 121.236 5.203 1.00 36.25 ? 389 LEU A N 1 ATOM 3073 C CA . LEU A 1 389 ? 60.849 121.632 6.502 1.00 36.87 ? 389 LEU A CA 1 ATOM 3074 C C . LEU A 1 389 ? 60.480 120.627 7.587 1.00 36.93 ? 389 LEU A C 1 ATOM 3075 O O . LEU A 1 389 ? 61.313 120.318 8.444 1.00 37.54 ? 389 LEU A O 1 ATOM 3076 C CB . LEU A 1 389 ? 60.448 123.081 6.928 1.00 36.49 ? 389 LEU A CB 1 ATOM 3077 C CG . LEU A 1 389 ? 61.233 123.597 8.153 1.00 37.00 ? 389 LEU A CG 1 ATOM 3078 C CD1 . LEU A 1 389 ? 62.732 123.689 7.880 1.00 37.62 ? 389 LEU A CD1 1 ATOM 3079 C CD2 . LEU A 1 389 ? 60.696 124.970 8.665 1.00 38.68 ? 389 LEU A CD2 1 ATOM 3080 N N . GLY A 1 390 ? 59.245 120.130 7.551 1.00 37.74 ? 390 GLY A N 1 ATOM 3081 C CA . GLY A 1 390 ? 58.818 119.089 8.497 1.00 38.23 ? 390 GLY A CA 1 ATOM 3082 C C . GLY A 1 390 ? 59.634 117.823 8.329 1.00 37.57 ? 390 GLY A C 1 ATOM 3083 O O . GLY A 1 390 ? 60.102 117.251 9.305 1.00 36.68 ? 390 GLY A O 1 ATOM 3084 N N . ASP A 1 391 ? 59.815 117.397 7.080 1.00 37.99 ? 391 ASP A N 1 ATOM 3085 C CA . ASP A 1 391 ? 60.701 116.252 6.775 1.00 38.35 ? 391 ASP A CA 1 ATOM 3086 C C . ASP A 1 391 ? 62.150 116.467 7.218 1.00 37.60 ? 391 ASP A C 1 ATOM 3087 O O . ASP A 1 391 ? 62.758 115.583 7.826 1.00 37.88 ? 391 ASP A O 1 ATOM 3088 C CB . ASP A 1 391 ? 60.603 115.874 5.300 1.00 38.67 ? 391 ASP A CB 1 ATOM 3089 C CG . ASP A 1 391 ? 59.272 115.219 4.978 1.00 42.30 ? 391 ASP A CG 1 ATOM 3090 O OD1 . ASP A 1 391 ? 58.790 114.414 5.819 1.00 45.65 ? 391 ASP A OD1 1 ATOM 3091 O OD2 . ASP A 1 391 ? 58.639 115.425 3.931 1.00 43.55 ? 391 ASP A OD2 1 ATOM 3092 N N . VAL A 1 392 ? 62.689 117.657 6.979 1.00 36.73 ? 392 VAL A N 1 ATOM 3093 C CA . VAL A 1 392 ? 64.032 117.958 7.438 1.00 35.84 ? 392 VAL A CA 1 ATOM 3094 C C . VAL A 1 392 ? 64.074 117.679 8.929 1.00 35.93 ? 392 VAL A C 1 ATOM 3095 O O . VAL A 1 392 ? 64.940 116.940 9.397 1.00 35.06 ? 392 VAL A O 1 ATOM 3096 C CB . VAL A 1 392 ? 64.435 119.438 7.120 1.00 35.90 ? 392 VAL A CB 1 ATOM 3097 C CG1 . VAL A 1 392 ? 65.622 119.857 7.921 1.00 34.30 ? 392 VAL A CG1 1 ATOM 3098 C CG2 . VAL A 1 392 ? 64.760 119.573 5.645 1.00 36.91 ? 392 VAL A CG2 1 ATOM 3099 N N . VAL A 1 393 ? 63.124 118.276 9.665 1.00 35.19 ? 393 VAL A N 1 ATOM 3100 C CA . VAL A 1 393 ? 63.165 118.209 11.124 1.00 35.12 ? 393 VAL A CA 1 ATOM 3101 C C . VAL A 1 393 ? 62.968 116.783 11.615 1.00 34.02 ? 393 VAL A C 1 ATOM 3102 O O . VAL A 1 393 ? 63.671 116.360 12.526 1.00 35.64 ? 393 VAL A O 1 ATOM 3103 C CB . VAL A 1 393 ? 62.150 119.199 11.823 1.00 34.81 ? 393 VAL A CB 1 ATOM 3104 C CG1 . VAL A 1 393 ? 62.077 118.922 13.349 1.00 33.81 ? 393 VAL A CG1 1 ATOM 3105 C CG2 . VAL A 1 393 ? 62.539 120.678 11.530 1.00 34.47 ? 393 VAL A CG2 1 ATOM 3106 N N . GLY A 1 394 ? 62.017 116.067 11.037 1.00 32.76 ? 394 GLY A N 1 ATOM 3107 C CA . GLY A 1 394 ? 61.729 114.688 11.457 1.00 33.27 ? 394 GLY A CA 1 ATOM 3108 C C . GLY A 1 394 ? 62.859 113.706 11.123 1.00 32.94 ? 394 GLY A C 1 ATOM 3109 O O . GLY A 1 394 ? 63.225 112.879 11.946 1.00 32.90 ? 394 GLY A O 1 ATOM 3110 N N . ASP A 1 395 ? 63.384 113.784 9.902 1.00 32.61 ? 395 ASP A N 1 ATOM 3111 C CA . ASP A 1 395 ? 64.491 112.898 9.481 1.00 32.82 ? 395 ASP A CA 1 ATOM 3112 C C . ASP A 1 395 ? 65.731 113.072 10.336 1.00 32.85 ? 395 ASP A C 1 ATOM 3113 O O . ASP A 1 395 ? 66.311 112.095 10.812 1.00 33.92 ? 395 ASP A O 1 ATOM 3114 C CB . ASP A 1 395 ? 64.827 113.118 8.002 1.00 32.66 ? 395 ASP A CB 1 ATOM 3115 C CG . ASP A 1 395 ? 63.668 112.698 7.077 1.00 34.76 ? 395 ASP A CG 1 ATOM 3116 O OD1 . ASP A 1 395 ? 63.708 113.021 5.870 1.00 34.34 ? 395 ASP A OD1 1 ATOM 3117 O OD2 . ASP A 1 395 ? 62.646 112.090 7.498 1.00 33.55 ? 395 ASP A OD2 1 ATOM 3118 N N . TYR A 1 396 ? 66.136 114.321 10.533 1.00 32.91 ? 396 TYR A N 1 ATOM 3119 C CA . TYR A 1 396 ? 67.374 114.641 11.218 1.00 31.98 ? 396 TYR A CA 1 ATOM 3120 C C . TYR A 1 396 ? 67.235 114.249 12.660 1.00 31.93 ? 396 TYR A C 1 ATOM 3121 O O . TYR A 1 396 ? 68.097 113.624 13.212 1.00 32.35 ? 396 TYR A O 1 ATOM 3122 C CB . TYR A 1 396 ? 67.663 116.141 11.104 1.00 31.38 ? 396 TYR A CB 1 ATOM 3123 C CG . TYR A 1 396 ? 68.819 116.634 11.962 1.00 32.94 ? 396 TYR A CG 1 ATOM 3124 C CD1 . TYR A 1 396 ? 70.115 116.074 11.836 1.00 31.82 ? 396 TYR A CD1 1 ATOM 3125 C CD2 . TYR A 1 396 ? 68.629 117.661 12.873 1.00 31.16 ? 396 TYR A CD2 1 ATOM 3126 C CE1 . TYR A 1 396 ? 71.186 116.544 12.600 1.00 35.24 ? 396 TYR A CE1 1 ATOM 3127 C CE2 . TYR A 1 396 ? 69.691 118.143 13.656 1.00 34.79 ? 396 TYR A CE2 1 ATOM 3128 C CZ . TYR A 1 396 ? 70.968 117.588 13.493 1.00 34.74 ? 396 TYR A CZ 1 ATOM 3129 O OH . TYR A 1 396 ? 71.999 118.031 14.254 1.00 37.62 ? 396 TYR A OH 1 ATOM 3130 N N . ASN A 1 397 ? 66.129 114.625 13.278 1.00 32.31 ? 397 ASN A N 1 ATOM 3131 C CA . ASN A 1 397 ? 66.000 114.448 14.718 1.00 32.90 ? 397 ASN A CA 1 ATOM 3132 C C . ASN A 1 397 ? 65.513 113.107 15.197 1.00 31.65 ? 397 ASN A C 1 ATOM 3133 O O . ASN A 1 397 ? 65.833 112.730 16.311 1.00 31.06 ? 397 ASN A O 1 ATOM 3134 C CB . ASN A 1 397 ? 65.098 115.558 15.298 1.00 32.92 ? 397 ASN A CB 1 ATOM 3135 C CG . ASN A 1 397 ? 65.827 116.853 15.379 1.00 34.55 ? 397 ASN A CG 1 ATOM 3136 O OD1 . ASN A 1 397 ? 66.710 117.028 16.243 1.00 31.67 ? 397 ASN A OD1 1 ATOM 3137 N ND2 . ASN A 1 397 ? 65.504 117.767 14.471 1.00 30.98 ? 397 ASN A ND2 1 ATOM 3138 N N . PHE A 1 398 ? 64.724 112.402 14.380 1.00 31.17 ? 398 PHE A N 1 ATOM 3139 C CA . PHE A 1 398 ? 64.097 111.152 14.860 1.00 31.18 ? 398 PHE A CA 1 ATOM 3140 C C . PHE A 1 398 ? 64.294 109.929 13.930 1.00 30.85 ? 398 PHE A C 1 ATOM 3141 O O . PHE A 1 398 ? 64.736 108.876 14.382 1.00 29.93 ? 398 PHE A O 1 ATOM 3142 C CB . PHE A 1 398 ? 62.598 111.367 15.152 1.00 30.65 ? 398 PHE A CB 1 ATOM 3143 C CG . PHE A 1 398 ? 62.336 112.444 16.174 1.00 31.35 ? 398 PHE A CG 1 ATOM 3144 C CD1 . PHE A 1 398 ? 61.992 113.735 15.753 1.00 31.03 ? 398 PHE A CD1 1 ATOM 3145 C CD2 . PHE A 1 398 ? 62.507 112.189 17.526 1.00 26.36 ? 398 PHE A CD2 1 ATOM 3146 C CE1 . PHE A 1 398 ? 61.762 114.803 16.679 1.00 30.87 ? 398 PHE A CE1 1 ATOM 3147 C CE2 . PHE A 1 398 ? 62.291 113.214 18.478 1.00 33.68 ? 398 PHE A CE2 1 ATOM 3148 C CZ . PHE A 1 398 ? 61.906 114.560 18.038 1.00 31.08 ? 398 PHE A CZ 1 ATOM 3149 N N . ILE A 1 399 ? 63.920 110.070 12.663 1.00 30.74 ? 399 ILE A N 1 ATOM 3150 C CA . ILE A 1 399 ? 63.773 108.885 11.794 1.00 31.92 ? 399 ILE A CA 1 ATOM 3151 C C . ILE A 1 399 ? 65.155 108.286 11.450 1.00 32.35 ? 399 ILE A C 1 ATOM 3152 O O . ILE A 1 399 ? 65.423 107.123 11.737 1.00 32.78 ? 399 ILE A O 1 ATOM 3153 C CB . ILE A 1 399 ? 62.960 109.218 10.527 1.00 31.97 ? 399 ILE A CB 1 ATOM 3154 C CG1 . ILE A 1 399 ? 61.497 109.577 10.896 1.00 31.64 ? 399 ILE A CG1 1 ATOM 3155 C CG2 . ILE A 1 399 ? 62.985 108.025 9.566 1.00 32.11 ? 399 ILE A CG2 1 ATOM 3156 C CD1 . ILE A 1 399 ? 60.613 109.792 9.720 1.00 35.72 ? 399 ILE A CD1 1 ATOM 3157 N N . CYS A 1 400 ? 66.047 109.101 10.878 1.00 33.50 ? 400 CYS A N 1 ATOM 3158 C CA . CYS A 1 400 ? 67.373 108.611 10.525 1.00 32.53 ? 400 CYS A CA 1 ATOM 3159 C C . CYS A 1 400 ? 68.164 108.091 11.724 1.00 32.77 ? 400 CYS A C 1 ATOM 3160 O O . CYS A 1 400 ? 68.799 107.043 11.575 1.00 31.94 ? 400 CYS A O 1 ATOM 3161 C CB . CYS A 1 400 ? 68.144 109.662 9.748 1.00 33.85 ? 400 CYS A CB 1 ATOM 3162 S SG . CYS A 1 400 ? 67.248 110.114 8.239 1.00 36.21 ? 400 CYS A SG 1 ATOM 3163 N N . PRO A 1 401 ? 68.167 108.776 12.895 1.00 31.55 ? 401 PRO A N 1 ATOM 3164 C CA . PRO A 1 401 ? 68.786 108.174 14.056 1.00 31.42 ? 401 PRO A CA 1 ATOM 3165 C C . PRO A 1 401 ? 68.148 106.832 14.491 1.00 32.23 ? 401 PRO A C 1 ATOM 3166 O O . PRO A 1 401 ? 68.910 105.915 14.862 1.00 32.45 ? 401 PRO A O 1 ATOM 3167 C CB . PRO A 1 401 ? 68.683 109.254 15.167 1.00 30.87 ? 401 PRO A CB 1 ATOM 3168 C CG . PRO A 1 401 ? 68.457 110.514 14.494 1.00 30.54 ? 401 PRO A CG 1 ATOM 3169 C CD . PRO A 1 401 ? 67.717 110.155 13.177 1.00 31.60 ? 401 PRO A CD 1 ATOM 3170 N N . ALA A 1 402 ? 66.808 106.693 14.459 1.00 31.19 ? 402 ALA A N 1 ATOM 3171 C CA . ALA A 1 402 ? 66.212 105.420 14.908 1.00 31.28 ? 402 ALA A CA 1 ATOM 3172 C C . ALA A 1 402 ? 66.652 104.307 13.950 1.00 31.26 ? 402 ALA A C 1 ATOM 3173 O O . ALA A 1 402 ? 66.952 103.180 14.366 1.00 30.68 ? 402 ALA A O 1 ATOM 3174 C CB . ALA A 1 402 ? 64.612 105.487 15.009 1.00 29.53 ? 402 ALA A CB 1 ATOM 3175 N N . LEU A 1 403 ? 66.681 104.638 12.667 1.00 31.25 ? 403 LEU A N 1 ATOM 3176 C CA . LEU A 1 403 ? 67.034 103.648 11.646 1.00 32.33 ? 403 LEU A CA 1 ATOM 3177 C C . LEU A 1 403 ? 68.501 103.230 11.784 1.00 32.81 ? 403 LEU A C 1 ATOM 3178 O O . LEU A 1 403 ? 68.813 102.034 11.736 1.00 32.99 ? 403 LEU A O 1 ATOM 3179 C CB . LEU A 1 403 ? 66.744 104.188 10.240 1.00 32.87 ? 403 LEU A CB 1 ATOM 3180 C CG . LEU A 1 403 ? 65.295 104.210 9.783 1.00 32.48 ? 403 LEU A CG 1 ATOM 3181 C CD1 . LEU A 1 403 ? 65.188 105.063 8.512 1.00 32.20 ? 403 LEU A CD1 1 ATOM 3182 C CD2 . LEU A 1 403 ? 64.809 102.772 9.557 1.00 29.44 ? 403 LEU A CD2 1 ATOM 3183 N N . GLU A 1 404 ? 69.371 104.195 12.066 1.00 33.28 ? 404 GLU A N 1 ATOM 3184 C CA . GLU A 1 404 ? 70.801 103.910 12.286 1.00 34.81 ? 404 GLU A CA 1 ATOM 3185 C C . GLU A 1 404 ? 71.079 103.094 13.568 1.00 34.11 ? 404 GLU A C 1 ATOM 3186 O O . GLU A 1 404 ? 71.923 102.180 13.576 1.00 33.74 ? 404 GLU A O 1 ATOM 3187 C CB . GLU A 1 404 ? 71.608 105.221 12.303 1.00 34.52 ? 404 GLU A CB 1 ATOM 3188 C CG . GLU A 1 404 ? 73.120 105.002 12.305 1.00 41.79 ? 404 GLU A CG 1 ATOM 3189 C CD . GLU A 1 404 ? 73.669 104.312 11.001 1.00 49.30 ? 404 GLU A CD 1 ATOM 3190 O OE1 . GLU A 1 404 ? 72.978 104.215 9.935 1.00 45.81 ? 404 GLU A OE1 1 ATOM 3191 O OE2 . GLU A 1 404 ? 74.842 103.886 11.048 1.00 55.67 ? 404 GLU A OE2 1 ATOM 3192 N N . PHE A 1 405 ? 70.403 103.472 14.659 1.00 33.45 ? 405 PHE A N 1 ATOM 3193 C CA . PHE A 1 405 ? 70.426 102.705 15.890 1.00 31.61 ? 405 PHE A CA 1 ATOM 3194 C C . PHE A 1 405 ? 70.054 101.225 15.607 1.00 31.70 ? 405 PHE A C 1 ATOM 3195 O O . PHE A 1 405 ? 70.731 100.262 16.052 1.00 31.35 ? 405 PHE A O 1 ATOM 3196 C CB . PHE A 1 405 ? 69.422 103.285 16.892 1.00 31.08 ? 405 PHE A CB 1 ATOM 3197 C CG . PHE A 1 405 ? 69.400 102.504 18.140 1.00 33.32 ? 405 PHE A CG 1 ATOM 3198 C CD1 . PHE A 1 405 ? 70.402 102.711 19.110 1.00 32.92 ? 405 PHE A CD1 1 ATOM 3199 C CD2 . PHE A 1 405 ? 68.511 101.436 18.287 1.00 31.00 ? 405 PHE A CD2 1 ATOM 3200 C CE1 . PHE A 1 405 ? 70.452 101.905 20.251 1.00 33.18 ? 405 PHE A CE1 1 ATOM 3201 C CE2 . PHE A 1 405 ? 68.558 100.632 19.417 1.00 34.09 ? 405 PHE A CE2 1 ATOM 3202 C CZ . PHE A 1 405 ? 69.499 100.901 20.422 1.00 32.19 ? 405 PHE A CZ 1 ATOM 3203 N N . THR A 1 406 ? 68.964 101.045 14.860 1.00 30.49 ? 406 THR A N 1 ATOM 3204 C CA . THR A 1 406 ? 68.478 99.726 14.543 1.00 31.54 ? 406 THR A CA 1 ATOM 3205 C C . THR A 1 406 ? 69.465 98.891 13.671 1.00 31.58 ? 406 THR A C 1 ATOM 3206 O O . THR A 1 406 ? 69.708 97.719 13.971 1.00 31.50 ? 406 THR A O 1 ATOM 3207 C CB . THR A 1 406 ? 67.077 99.844 13.891 1.00 30.99 ? 406 THR A CB 1 ATOM 3208 O OG1 . THR A 1 406 ? 66.230 100.620 14.763 1.00 34.46 ? 406 THR A OG1 1 ATOM 3209 C CG2 . THR A 1 406 ? 66.394 98.449 13.783 1.00 30.49 ? 406 THR A CG2 1 ATOM 3210 N N . LYS A 1 407 ? 70.016 99.478 12.618 1.00 32.60 ? 407 LYS A N 1 ATOM 3211 C CA . LYS A 1 407 ? 71.042 98.789 11.828 1.00 35.15 ? 407 LYS A CA 1 ATOM 3212 C C . LYS A 1 407 ? 72.182 98.368 12.712 1.00 35.15 ? 407 LYS A C 1 ATOM 3213 O O . LYS A 1 407 ? 72.557 97.187 12.741 1.00 36.17 ? 407 LYS A O 1 ATOM 3214 C CB . LYS A 1 407 ? 71.611 99.678 10.737 1.00 34.55 ? 407 LYS A CB 1 ATOM 3215 C CG . LYS A 1 407 ? 70.645 100.030 9.722 1.00 40.99 ? 407 LYS A CG 1 ATOM 3216 C CD . LYS A 1 407 ? 71.275 100.964 8.684 1.00 47.81 ? 407 LYS A CD 1 ATOM 3217 C CE . LYS A 1 407 ? 70.187 101.776 7.990 1.00 49.15 ? 407 LYS A CE 1 ATOM 3218 N NZ . LYS A 1 407 ? 70.729 102.519 6.805 1.00 50.72 ? 407 LYS A NZ 1 ATOM 3219 N N . LYS A 1 408 ? 72.748 99.331 13.427 1.00 34.90 ? 408 LYS A N 1 ATOM 3220 C CA . LYS A 1 408 ? 73.953 99.050 14.217 1.00 35.89 ? 408 LYS A CA 1 ATOM 3221 C C . LYS A 1 408 ? 73.742 98.022 15.307 1.00 35.77 ? 408 LYS A C 1 ATOM 3222 O O . LYS A 1 408 ? 74.646 97.229 15.598 1.00 36.28 ? 408 LYS A O 1 ATOM 3223 C CB . LYS A 1 408 ? 74.565 100.317 14.794 1.00 34.17 ? 408 LYS A CB 1 ATOM 3224 C CG . LYS A 1 408 ? 75.123 101.230 13.754 1.00 40.15 ? 408 LYS A CG 1 ATOM 3225 C CD . LYS A 1 408 ? 76.456 100.719 13.223 1.00 50.63 ? 408 LYS A CD 1 ATOM 3226 C CE . LYS A 1 408 ? 77.004 101.626 12.109 1.00 55.83 ? 408 LYS A CE 1 ATOM 3227 N NZ . LYS A 1 408 ? 78.382 101.187 11.670 1.00 60.39 ? 408 LYS A NZ 1 ATOM 3228 N N . PHE A 1 409 ? 72.563 98.041 15.915 1.00 35.98 ? 409 PHE A N 1 ATOM 3229 C CA . PHE A 1 409 ? 72.233 97.111 17.001 1.00 35.54 ? 409 PHE A CA 1 ATOM 3230 C C . PHE A 1 409 ? 72.036 95.697 16.432 1.00 36.40 ? 409 PHE A C 1 ATOM 3231 O O . PHE A 1 409 ? 72.452 94.687 17.037 1.00 36.10 ? 409 PHE A O 1 ATOM 3232 C CB . PHE A 1 409 ? 70.960 97.575 17.730 1.00 34.66 ? 409 PHE A CB 1 ATOM 3233 C CG . PHE A 1 409 ? 70.691 96.831 19.057 1.00 35.34 ? 409 PHE A CG 1 ATOM 3234 C CD1 . PHE A 1 409 ? 71.076 97.388 20.268 1.00 31.19 ? 409 PHE A CD1 1 ATOM 3235 C CD2 . PHE A 1 409 ? 70.069 95.578 19.068 1.00 31.28 ? 409 PHE A CD2 1 ATOM 3236 C CE1 . PHE A 1 409 ? 70.838 96.687 21.483 1.00 33.35 ? 409 PHE A CE1 1 ATOM 3237 C CE2 . PHE A 1 409 ? 69.825 94.879 20.286 1.00 34.88 ? 409 PHE A CE2 1 ATOM 3238 C CZ . PHE A 1 409 ? 70.226 95.436 21.488 1.00 28.45 ? 409 PHE A CZ 1 ATOM 3239 N N . SER A 1 410 ? 71.363 95.624 15.278 1.00 36.36 ? 410 SER A N 1 ATOM 3240 C CA . SER A 1 410 ? 71.022 94.348 14.688 1.00 37.04 ? 410 SER A CA 1 ATOM 3241 C C . SER A 1 410 ? 72.299 93.648 14.156 1.00 38.27 ? 410 SER A C 1 ATOM 3242 O O . SER A 1 410 ? 72.355 92.422 14.074 1.00 36.90 ? 410 SER A O 1 ATOM 3243 C CB . SER A 1 410 ? 69.970 94.543 13.594 1.00 36.66 ? 410 SER A CB 1 ATOM 3244 O OG . SER A 1 410 ? 70.582 95.123 12.445 1.00 40.16 ? 410 SER A OG 1 ATOM 3245 N N . GLU A 1 411 ? 73.350 94.432 13.875 1.00 40.05 ? 411 GLU A N 1 ATOM 3246 C CA . GLU A 1 411 ? 74.585 93.884 13.311 1.00 41.38 ? 411 GLU A CA 1 ATOM 3247 C C . GLU A 1 411 ? 75.339 92.968 14.280 1.00 41.95 ? 411 GLU A C 1 ATOM 3248 O O . GLU A 1 411 ? 76.223 92.222 13.871 1.00 41.87 ? 411 GLU A O 1 ATOM 3249 C CB . GLU A 1 411 ? 75.485 94.999 12.832 1.00 42.09 ? 411 GLU A CB 1 ATOM 3250 C CG . GLU A 1 411 ? 75.290 95.295 11.352 1.00 46.05 ? 411 GLU A CG 1 ATOM 3251 C CD . GLU A 1 411 ? 75.705 96.710 11.002 1.00 54.39 ? 411 GLU A CD 1 ATOM 3252 O OE1 . GLU A 1 411 ? 76.612 97.264 11.688 1.00 57.01 ? 411 GLU A OE1 1 ATOM 3253 O OE2 . GLU A 1 411 ? 75.121 97.277 10.047 1.00 57.51 ? 411 GLU A OE2 1 ATOM 3254 N N . TRP A 1 412 ? 74.936 92.977 15.544 1.00 41.65 ? 412 TRP A N 1 ATOM 3255 C CA . TRP A 1 412 ? 75.571 92.156 16.558 1.00 41.26 ? 412 TRP A CA 1 ATOM 3256 C C . TRP A 1 412 ? 74.797 90.915 16.867 1.00 41.45 ? 412 TRP A C 1 ATOM 3257 O O . TRP A 1 412 ? 75.031 90.269 17.868 1.00 42.19 ? 412 TRP A O 1 ATOM 3258 C CB . TRP A 1 412 ? 75.832 92.994 17.801 1.00 41.32 ? 412 TRP A CB 1 ATOM 3259 C CG . TRP A 1 412 ? 76.952 93.939 17.500 1.00 41.38 ? 412 TRP A CG 1 ATOM 3260 C CD1 . TRP A 1 412 ? 76.860 95.167 16.927 1.00 41.20 ? 412 TRP A CD1 1 ATOM 3261 C CD2 . TRP A 1 412 ? 78.349 93.688 17.697 1.00 42.95 ? 412 TRP A CD2 1 ATOM 3262 N NE1 . TRP A 1 412 ? 78.111 95.722 16.777 1.00 42.49 ? 412 TRP A NE1 1 ATOM 3263 C CE2 . TRP A 1 412 ? 79.051 94.829 17.233 1.00 42.47 ? 412 TRP A CE2 1 ATOM 3264 C CE3 . TRP A 1 412 ? 79.084 92.617 18.241 1.00 43.38 ? 412 TRP A CE3 1 ATOM 3265 C CZ2 . TRP A 1 412 ? 80.467 94.935 17.290 1.00 45.52 ? 412 TRP A CZ2 1 ATOM 3266 C CZ3 . TRP A 1 412 ? 80.521 92.723 18.304 1.00 44.93 ? 412 TRP A CZ3 1 ATOM 3267 C CH2 . TRP A 1 412 ? 81.180 93.874 17.829 1.00 44.01 ? 412 TRP A CH2 1 ATOM 3268 N N . GLY A 1 413 ? 73.865 90.557 15.997 1.00 41.95 ? 413 GLY A N 1 ATOM 3269 C CA . GLY A 1 413 ? 73.236 89.266 16.130 1.00 41.64 ? 413 GLY A CA 1 ATOM 3270 C C . GLY A 1 413 ? 71.793 89.227 16.559 1.00 42.19 ? 413 GLY A C 1 ATOM 3271 O O . GLY A 1 413 ? 71.119 88.259 16.270 1.00 43.61 ? 413 GLY A O 1 ATOM 3272 N N . ASN A 1 414 ? 71.281 90.269 17.220 1.00 41.67 ? 414 ASN A N 1 ATOM 3273 C CA . ASN A 1 414 ? 69.964 90.133 17.826 1.00 39.98 ? 414 ASN A CA 1 ATOM 3274 C C . ASN A 1 414 ? 68.834 90.485 16.876 1.00 38.68 ? 414 ASN A C 1 ATOM 3275 O O . ASN A 1 414 ? 69.005 91.292 15.949 1.00 38.75 ? 414 ASN A O 1 ATOM 3276 C CB . ASN A 1 414 ? 69.857 90.974 19.091 1.00 40.77 ? 414 ASN A CB 1 ATOM 3277 C CG . ASN A 1 414 ? 70.743 90.468 20.236 1.00 40.01 ? 414 ASN A CG 1 ATOM 3278 O OD1 . ASN A 1 414 ? 71.723 91.138 20.566 1.00 37.05 ? 414 ASN A OD1 1 ATOM 3279 N ND2 . ASN A 1 414 ? 70.372 89.294 20.879 1.00 36.12 ? 414 ASN A ND2 1 ATOM 3280 N N . ASN A 1 415 ? 67.682 89.863 17.103 1.00 37.58 ? 415 ASN A N 1 ATOM 3281 C CA . ASN A 1 415 ? 66.469 90.200 16.390 1.00 37.21 ? 415 ASN A CA 1 ATOM 3282 C C . ASN A 1 415 ? 65.988 91.650 16.694 1.00 36.74 ? 415 ASN A C 1 ATOM 3283 O O . ASN A 1 415 ? 65.891 92.055 17.844 1.00 36.84 ? 415 ASN A O 1 ATOM 3284 C CB . ASN A 1 415 ? 65.360 89.190 16.730 1.00 37.51 ? 415 ASN A CB 1 ATOM 3285 C CG . ASN A 1 415 ? 65.479 87.894 15.939 1.00 39.00 ? 415 ASN A CG 1 ATOM 3286 O OD1 . ASN A 1 415 ? 66.376 87.735 15.100 1.00 40.03 ? 415 ASN A OD1 1 ATOM 3287 N ND2 . ASN A 1 415 ? 64.570 86.973 16.197 1.00 35.84 ? 415 ASN A ND2 1 ATOM 3288 N N . ALA A 1 416 ? 65.709 92.407 15.643 1.00 35.05 ? 416 ALA A N 1 ATOM 3289 C CA . ALA A 1 416 ? 65.166 93.737 15.776 1.00 34.15 ? 416 ALA A CA 1 ATOM 3290 C C . ALA A 1 416 ? 64.001 93.831 14.815 1.00 33.62 ? 416 ALA A C 1 ATOM 3291 O O . ALA A 1 416 ? 64.039 93.234 13.701 1.00 33.20 ? 416 ALA A O 1 ATOM 3292 C CB . ALA A 1 416 ? 66.208 94.765 15.441 1.00 33.95 ? 416 ALA A CB 1 ATOM 3293 N N . PHE A 1 417 ? 62.982 94.585 15.244 1.00 31.97 ? 417 PHE A N 1 ATOM 3294 C CA . PHE A 1 417 ? 61.759 94.829 14.481 1.00 32.12 ? 417 PHE A CA 1 ATOM 3295 C C . PHE A 1 417 ? 61.533 96.334 14.384 1.00 32.05 ? 417 PHE A C 1 ATOM 3296 O O . PHE A 1 417 ? 61.536 97.041 15.413 1.00 31.68 ? 417 PHE A O 1 ATOM 3297 C CB . PHE A 1 417 ? 60.564 94.118 15.179 1.00 32.77 ? 417 PHE A CB 1 ATOM 3298 C CG . PHE A 1 417 ? 60.828 92.641 15.461 1.00 33.20 ? 417 PHE A CG 1 ATOM 3299 C CD1 . PHE A 1 417 ? 61.484 92.247 16.619 1.00 30.12 ? 417 PHE A CD1 1 ATOM 3300 C CD2 . PHE A 1 417 ? 60.479 91.659 14.507 1.00 33.41 ? 417 PHE A CD2 1 ATOM 3301 C CE1 . PHE A 1 417 ? 61.763 90.922 16.868 1.00 30.71 ? 417 PHE A CE1 1 ATOM 3302 C CE2 . PHE A 1 417 ? 60.755 90.306 14.748 1.00 33.01 ? 417 PHE A CE2 1 ATOM 3303 C CZ . PHE A 1 417 ? 61.397 89.933 15.908 1.00 32.32 ? 417 PHE A CZ 1 ATOM 3304 N N . PHE A 1 418 ? 61.348 96.836 13.162 1.00 31.06 ? 418 PHE A N 1 ATOM 3305 C CA . PHE A 1 418 ? 61.172 98.269 12.951 1.00 30.80 ? 418 PHE A CA 1 ATOM 3306 C C . PHE A 1 418 ? 59.746 98.566 12.419 1.00 31.41 ? 418 PHE A C 1 ATOM 3307 O O . PHE A 1 418 ? 59.243 97.810 11.549 1.00 30.84 ? 418 PHE A O 1 ATOM 3308 C CB . PHE A 1 418 ? 62.262 98.799 11.975 1.00 29.64 ? 418 PHE A CB 1 ATOM 3309 C CG . PHE A 1 418 ? 62.378 100.259 12.002 1.00 29.66 ? 418 PHE A CG 1 ATOM 3310 C CD1 . PHE A 1 418 ? 61.473 101.048 11.291 1.00 28.70 ? 418 PHE A CD1 1 ATOM 3311 C CD2 . PHE A 1 418 ? 63.321 100.883 12.846 1.00 27.76 ? 418 PHE A CD2 1 ATOM 3312 C CE1 . PHE A 1 418 ? 61.539 102.437 11.375 1.00 29.38 ? 418 PHE A CE1 1 ATOM 3313 C CE2 . PHE A 1 418 ? 63.393 102.258 12.915 1.00 27.82 ? 418 PHE A CE2 1 ATOM 3314 C CZ . PHE A 1 418 ? 62.519 103.038 12.176 1.00 26.02 ? 418 PHE A CZ 1 ATOM 3315 N N . TYR A 1 419 ? 59.067 99.612 12.938 1.00 30.53 ? 419 TYR A N 1 ATOM 3316 C CA . TYR A 1 419 ? 57.717 99.962 12.407 1.00 30.97 ? 419 TYR A CA 1 ATOM 3317 C C . TYR A 1 419 ? 57.711 101.402 11.883 1.00 32.34 ? 419 TYR A C 1 ATOM 3318 O O . TYR A 1 419 ? 58.549 102.209 12.275 1.00 31.79 ? 419 TYR A O 1 ATOM 3319 C CB . TYR A 1 419 ? 56.555 99.767 13.436 1.00 31.90 ? 419 TYR A CB 1 ATOM 3320 C CG . TYR A 1 419 ? 56.647 100.725 14.629 1.00 28.37 ? 419 TYR A CG 1 ATOM 3321 C CD1 . TYR A 1 419 ? 57.269 100.351 15.790 1.00 31.26 ? 419 TYR A CD1 1 ATOM 3322 C CD2 . TYR A 1 419 ? 56.158 102.028 14.527 1.00 27.96 ? 419 TYR A CD2 1 ATOM 3323 C CE1 . TYR A 1 419 ? 57.392 101.268 16.907 1.00 33.54 ? 419 TYR A CE1 1 ATOM 3324 C CE2 . TYR A 1 419 ? 56.242 102.915 15.565 1.00 29.71 ? 419 TYR A CE2 1 ATOM 3325 C CZ . TYR A 1 419 ? 56.878 102.555 16.754 1.00 32.06 ? 419 TYR A CZ 1 ATOM 3326 O OH . TYR A 1 419 ? 56.984 103.506 17.763 1.00 30.66 ? 419 TYR A OH 1 ATOM 3327 N N . TYR A 1 420 ? 56.770 101.705 10.981 1.00 33.09 ? 420 TYR A N 1 ATOM 3328 C CA . TYR A 1 420 ? 56.555 103.047 10.503 1.00 33.38 ? 420 TYR A CA 1 ATOM 3329 C C . TYR A 1 420 ? 55.065 103.302 10.744 1.00 34.59 ? 420 TYR A C 1 ATOM 3330 O O . TYR A 1 420 ? 54.191 102.706 10.084 1.00 33.93 ? 420 TYR A O 1 ATOM 3331 C CB . TYR A 1 420 ? 56.866 103.111 9.000 1.00 33.11 ? 420 TYR A CB 1 ATOM 3332 C CG . TYR A 1 420 ? 56.794 104.483 8.368 1.00 32.44 ? 420 TYR A CG 1 ATOM 3333 C CD1 . TYR A 1 420 ? 57.560 105.538 8.872 1.00 31.00 ? 420 TYR A CD1 1 ATOM 3334 C CD2 . TYR A 1 420 ? 56.012 104.716 7.227 1.00 32.66 ? 420 TYR A CD2 1 ATOM 3335 C CE1 . TYR A 1 420 ? 57.560 106.807 8.248 1.00 33.88 ? 420 TYR A CE1 1 ATOM 3336 C CE2 . TYR A 1 420 ? 55.993 105.973 6.612 1.00 33.14 ? 420 TYR A CE2 1 ATOM 3337 C CZ . TYR A 1 420 ? 56.775 107.008 7.131 1.00 32.75 ? 420 TYR A CZ 1 ATOM 3338 O OH . TYR A 1 420 ? 56.779 108.246 6.547 1.00 35.74 ? 420 TYR A OH 1 ATOM 3339 N N . PHE A 1 421 ? 54.788 104.126 11.745 1.00 34.97 ? 421 PHE A N 1 ATOM 3340 C CA . PHE A 1 421 ? 53.417 104.389 12.144 1.00 35.71 ? 421 PHE A CA 1 ATOM 3341 C C . PHE A 1 421 ? 52.884 105.507 11.256 1.00 35.17 ? 421 PHE A C 1 ATOM 3342 O O . PHE A 1 421 ? 53.382 106.654 11.265 1.00 35.19 ? 421 PHE A O 1 ATOM 3343 C CB . PHE A 1 421 ? 53.362 104.743 13.642 1.00 34.31 ? 421 PHE A CB 1 ATOM 3344 C CG . PHE A 1 421 ? 51.982 105.016 14.162 1.00 36.27 ? 421 PHE A CG 1 ATOM 3345 C CD1 . PHE A 1 421 ? 51.134 103.975 14.538 1.00 37.61 ? 421 PHE A CD1 1 ATOM 3346 C CD2 . PHE A 1 421 ? 51.542 106.322 14.326 1.00 36.46 ? 421 PHE A CD2 1 ATOM 3347 C CE1 . PHE A 1 421 ? 49.835 104.243 15.033 1.00 37.75 ? 421 PHE A CE1 1 ATOM 3348 C CE2 . PHE A 1 421 ? 50.285 106.600 14.831 1.00 36.29 ? 421 PHE A CE2 1 ATOM 3349 C CZ . PHE A 1 421 ? 49.414 105.563 15.184 1.00 35.54 ? 421 PHE A CZ 1 ATOM 3350 N N . GLU A 1 422 ? 51.870 105.182 10.478 1.00 36.13 ? 422 GLU A N 1 ATOM 3351 C CA . GLU A 1 422 ? 51.377 106.169 9.539 1.00 37.99 ? 422 GLU A CA 1 ATOM 3352 C C . GLU A 1 422 ? 49.869 106.426 9.693 1.00 38.93 ? 422 GLU A C 1 ATOM 3353 O O . GLU A 1 422 ? 49.198 106.796 8.739 1.00 38.67 ? 422 GLU A O 1 ATOM 3354 C CB . GLU A 1 422 ? 51.788 105.789 8.096 1.00 38.85 ? 422 GLU A CB 1 ATOM 3355 C CG . GLU A 1 422 ? 51.390 104.389 7.719 1.00 41.68 ? 422 GLU A CG 1 ATOM 3356 C CD . GLU A 1 422 ? 51.837 103.972 6.314 1.00 45.47 ? 422 GLU A CD 1 ATOM 3357 O OE1 . GLU A 1 422 ? 52.735 104.612 5.737 1.00 43.89 ? 422 GLU A OE1 1 ATOM 3358 O OE2 . GLU A 1 422 ? 51.288 102.962 5.811 1.00 48.07 ? 422 GLU A OE2 1 ATOM 3359 N N . HIS A 1 423 ? 49.333 106.267 10.905 1.00 39.08 ? 423 HIS A N 1 ATOM 3360 C CA . HIS A 1 423 ? 47.930 106.603 11.100 1.00 39.84 ? 423 HIS A CA 1 ATOM 3361 C C . HIS A 1 423 ? 47.719 107.936 11.846 1.00 40.05 ? 423 HIS A C 1 ATOM 3362 O O . HIS A 1 423 ? 48.220 108.107 12.960 1.00 38.72 ? 423 HIS A O 1 ATOM 3363 C CB . HIS A 1 423 ? 47.184 105.489 11.834 1.00 39.90 ? 423 HIS A CB 1 ATOM 3364 C CG . HIS A 1 423 ? 45.753 105.835 12.082 1.00 42.49 ? 423 HIS A CG 1 ATOM 3365 N ND1 . HIS A 1 423 ? 44.833 105.937 11.059 1.00 44.08 ? 423 HIS A ND1 1 ATOM 3366 C CD2 . HIS A 1 423 ? 45.101 106.189 13.217 1.00 44.55 ? 423 HIS A CD2 1 ATOM 3367 C CE1 . HIS A 1 423 ? 43.673 106.333 11.556 1.00 45.41 ? 423 HIS A CE1 1 ATOM 3368 N NE2 . HIS A 1 423 ? 43.807 106.478 12.863 1.00 43.96 ? 423 HIS A NE2 1 ATOM 3369 N N . ARG A 1 424 ? 46.960 108.852 11.241 1.00 40.78 ? 424 ARG A N 1 ATOM 3370 C CA . ARG A 1 424 ? 46.531 110.077 11.935 1.00 42.54 ? 424 ARG A CA 1 ATOM 3371 C C . ARG A 1 424 ? 45.221 109.871 12.735 1.00 43.02 ? 424 ARG A C 1 ATOM 3372 O O . ARG A 1 424 ? 44.191 109.567 12.143 1.00 42.73 ? 424 ARG A O 1 ATOM 3373 C CB . ARG A 1 424 ? 46.334 111.228 10.951 1.00 42.37 ? 424 ARG A CB 1 ATOM 3374 C CG . ARG A 1 424 ? 46.018 112.571 11.647 1.00 43.38 ? 424 ARG A CG 1 ATOM 3375 C CD . ARG A 1 424 ? 45.834 113.686 10.670 1.00 45.97 ? 424 ARG A CD 1 ATOM 3376 N NE . ARG A 1 424 ? 45.024 114.800 11.162 1.00 49.19 ? 424 ARG A NE 1 ATOM 3377 C CZ . ARG A 1 424 ? 45.511 115.965 11.605 1.00 52.87 ? 424 ARG A CZ 1 ATOM 3378 N NH1 . ARG A 1 424 ? 46.850 116.187 11.672 1.00 52.58 ? 424 ARG A NH1 1 ATOM 3379 N NH2 . ARG A 1 424 ? 44.654 116.921 11.992 1.00 48.21 ? 424 ARG A NH2 1 ATOM 3380 N N . SER A 1 425 ? 45.282 110.026 14.059 1.00 43.22 ? 425 SER A N 1 ATOM 3381 C CA . SER A 1 425 ? 44.102 109.981 14.938 1.00 44.29 ? 425 SER A CA 1 ATOM 3382 C C . SER A 1 425 ? 42.923 110.831 14.377 1.00 44.31 ? 425 SER A C 1 ATOM 3383 O O . SER A 1 425 ? 43.109 111.972 13.964 1.00 44.76 ? 425 SER A O 1 ATOM 3384 C CB . SER A 1 425 ? 44.505 110.500 16.314 1.00 44.15 ? 425 SER A CB 1 ATOM 3385 O OG . SER A 1 425 ? 43.555 110.179 17.313 1.00 45.91 ? 425 SER A OG 1 ATOM 3386 N N . SER A 1 426 ? 41.736 110.251 14.312 1.00 44.62 ? 426 SER A N 1 ATOM 3387 C CA . SER A 1 426 ? 40.498 110.975 13.916 1.00 45.89 ? 426 SER A CA 1 ATOM 3388 C C . SER A 1 426 ? 40.170 112.082 14.934 1.00 46.84 ? 426 SER A C 1 ATOM 3389 O O . SER A 1 426 ? 39.460 113.014 14.626 1.00 46.68 ? 426 SER A O 1 ATOM 3390 C CB . SER A 1 426 ? 39.305 110.006 13.824 1.00 45.30 ? 426 SER A CB 1 ATOM 3391 O OG . SER A 1 426 ? 39.105 109.326 15.074 1.00 44.16 ? 426 SER A OG 1 ATOM 3392 N N . LYS A 1 427 ? 40.698 111.959 16.143 1.00 48.08 ? 427 LYS A N 1 ATOM 3393 C CA . LYS A 1 427 ? 40.480 112.953 17.188 1.00 49.54 ? 427 LYS A CA 1 ATOM 3394 C C . LYS A 1 427 ? 41.612 114.024 17.283 1.00 49.95 ? 427 LYS A C 1 ATOM 3395 O O . LYS A 1 427 ? 41.575 114.899 18.177 1.00 50.31 ? 427 LYS A O 1 ATOM 3396 C CB . LYS A 1 427 ? 40.313 112.238 18.543 1.00 49.46 ? 427 LYS A CB 1 ATOM 3397 C CG . LYS A 1 427 ? 39.298 111.082 18.549 1.00 51.64 ? 427 LYS A CG 1 ATOM 3398 C CD . LYS A 1 427 ? 39.182 110.434 19.951 1.00 55.05 ? 427 LYS A CD 1 ATOM 3399 C CE . LYS A 1 427 ? 38.808 111.482 21.060 1.00 57.40 ? 427 LYS A CE 1 ATOM 3400 N NZ . LYS A 1 427 ? 39.274 111.102 22.436 1.00 57.61 ? 427 LYS A NZ 1 ATOM 3401 N N . LEU A 1 428 ? 42.614 113.968 16.391 1.00 48.63 ? 428 LEU A N 1 ATOM 3402 C CA . LEU A 1 428 ? 43.796 114.844 16.530 1.00 46.71 ? 428 LEU A CA 1 ATOM 3403 C C . LEU A 1 428 ? 43.376 116.326 16.521 1.00 45.01 ? 428 LEU A C 1 ATOM 3404 O O . LEU A 1 428 ? 42.721 116.756 15.594 1.00 44.68 ? 428 LEU A O 1 ATOM 3405 C CB . LEU A 1 428 ? 44.836 114.529 15.423 1.00 46.97 ? 428 LEU A CB 1 ATOM 3406 C CG . LEU A 1 428 ? 46.370 114.639 15.600 1.00 47.50 ? 428 LEU A CG 1 ATOM 3407 C CD1 . LEU A 1 428 ? 46.920 115.833 14.918 1.00 47.77 ? 428 LEU A CD1 1 ATOM 3408 C CD2 . LEU A 1 428 ? 46.858 114.606 17.013 1.00 46.42 ? 428 LEU A CD2 1 ATOM 3409 N N . PRO A 1 429 ? 43.719 117.095 17.559 1.00 43.31 ? 429 PRO A N 1 ATOM 3410 C CA . PRO A 1 429 ? 43.319 118.510 17.639 1.00 42.25 ? 429 PRO A CA 1 ATOM 3411 C C . PRO A 1 429 ? 44.206 119.448 16.827 1.00 41.23 ? 429 PRO A C 1 ATOM 3412 O O . PRO A 1 429 ? 43.809 120.580 16.536 1.00 40.78 ? 429 PRO A O 1 ATOM 3413 C CB . PRO A 1 429 ? 43.440 118.838 19.138 1.00 41.60 ? 429 PRO A CB 1 ATOM 3414 C CG . PRO A 1 429 ? 44.206 117.772 19.730 1.00 42.36 ? 429 PRO A CG 1 ATOM 3415 C CD . PRO A 1 429 ? 44.482 116.674 18.736 1.00 43.17 ? 429 PRO A CD 1 ATOM 3416 N N . TRP A 1 430 ? 45.387 118.974 16.444 1.00 39.87 ? 430 TRP A N 1 ATOM 3417 C CA . TRP A 1 430 ? 46.259 119.736 15.564 1.00 39.58 ? 430 TRP A CA 1 ATOM 3418 C C . TRP A 1 430 ? 45.764 119.692 14.091 1.00 39.58 ? 430 TRP A C 1 ATOM 3419 O O . TRP A 1 430 ? 45.071 118.767 13.735 1.00 39.40 ? 430 TRP A O 1 ATOM 3420 C CB . TRP A 1 430 ? 47.666 119.160 15.664 1.00 39.41 ? 430 TRP A CB 1 ATOM 3421 C CG . TRP A 1 430 ? 48.311 119.245 17.052 1.00 34.87 ? 430 TRP A CG 1 ATOM 3422 C CD1 . TRP A 1 430 ? 48.349 118.259 18.020 1.00 34.49 ? 430 TRP A CD1 1 ATOM 3423 C CD2 . TRP A 1 430 ? 49.005 120.352 17.593 1.00 34.90 ? 430 TRP A CD2 1 ATOM 3424 N NE1 . TRP A 1 430 ? 49.039 118.696 19.128 1.00 33.32 ? 430 TRP A NE1 1 ATOM 3425 C CE2 . TRP A 1 430 ? 49.458 119.981 18.896 1.00 32.04 ? 430 TRP A CE2 1 ATOM 3426 C CE3 . TRP A 1 430 ? 49.306 121.639 17.121 1.00 34.10 ? 430 TRP A CE3 1 ATOM 3427 C CZ2 . TRP A 1 430 ? 50.175 120.830 19.699 1.00 32.31 ? 430 TRP A CZ2 1 ATOM 3428 C CZ3 . TRP A 1 430 ? 50.073 122.487 17.953 1.00 32.33 ? 430 TRP A CZ3 1 ATOM 3429 C CH2 . TRP A 1 430 ? 50.463 122.092 19.210 1.00 31.64 ? 430 TRP A CH2 1 ATOM 3430 N N . PRO A 1 431 ? 46.107 120.670 13.246 1.00 39.14 ? 431 PRO A N 1 ATOM 3431 C CA . PRO A 1 431 ? 45.605 120.666 11.858 1.00 40.43 ? 431 PRO A CA 1 ATOM 3432 C C . PRO A 1 431 ? 46.101 119.475 11.012 1.00 42.55 ? 431 PRO A C 1 ATOM 3433 O O . PRO A 1 431 ? 47.101 118.791 11.372 1.00 41.83 ? 431 PRO A O 1 ATOM 3434 C CB . PRO A 1 431 ? 46.120 121.978 11.267 1.00 39.48 ? 431 PRO A CB 1 ATOM 3435 C CG . PRO A 1 431 ? 47.287 122.409 12.213 1.00 40.58 ? 431 PRO A CG 1 ATOM 3436 C CD . PRO A 1 431 ? 46.939 121.848 13.558 1.00 38.57 ? 431 PRO A CD 1 ATOM 3437 N N . GLU A 1 432 ? 45.403 119.255 9.896 1.00 43.66 ? 432 GLU A N 1 ATOM 3438 C CA . GLU A 1 432 ? 45.695 118.187 8.953 1.00 46.51 ? 432 GLU A CA 1 ATOM 3439 C C . GLU A 1 432 ? 47.081 118.236 8.354 1.00 45.93 ? 432 GLU A C 1 ATOM 3440 O O . GLU A 1 432 ? 47.691 117.187 8.154 1.00 45.95 ? 432 GLU A O 1 ATOM 3441 C CB . GLU A 1 432 ? 44.643 118.113 7.837 1.00 47.25 ? 432 GLU A CB 1 ATOM 3442 C CG . GLU A 1 432 ? 43.533 117.124 8.163 1.00 55.22 ? 432 GLU A CG 1 ATOM 3443 C CD . GLU A 1 432 ? 43.707 115.785 7.449 1.00 65.30 ? 432 GLU A CD 1 ATOM 3444 O OE1 . GLU A 1 432 ? 43.540 115.754 6.194 1.00 69.02 ? 432 GLU A OE1 1 ATOM 3445 O OE2 . GLU A 1 432 ? 43.986 114.754 8.134 1.00 68.78 ? 432 GLU A OE2 1 ATOM 3446 N N . TRP A 1 433 ? 47.575 119.441 8.074 1.00 45.71 ? 433 TRP A N 1 ATOM 3447 C CA . TRP A 1 433 ? 48.890 119.574 7.415 1.00 45.58 ? 433 TRP A CA 1 ATOM 3448 C C . TRP A 1 433 ? 50.007 118.986 8.294 1.00 45.30 ? 433 TRP A C 1 ATOM 3449 O O . TRP A 1 433 ? 51.068 118.602 7.777 1.00 45.69 ? 433 TRP A O 1 ATOM 3450 C CB . TRP A 1 433 ? 49.200 121.030 7.051 1.00 45.06 ? 433 TRP A CB 1 ATOM 3451 C CG . TRP A 1 433 ? 49.556 121.970 8.178 1.00 45.06 ? 433 TRP A CG 1 ATOM 3452 C CD1 . TRP A 1 433 ? 48.750 122.926 8.714 1.00 43.69 ? 433 TRP A CD1 1 ATOM 3453 C CD2 . TRP A 1 433 ? 50.838 122.111 8.855 1.00 45.73 ? 433 TRP A CD2 1 ATOM 3454 N NE1 . TRP A 1 433 ? 49.424 123.636 9.683 1.00 42.75 ? 433 TRP A NE1 1 ATOM 3455 C CE2 . TRP A 1 433 ? 50.700 123.158 9.798 1.00 43.02 ? 433 TRP A CE2 1 ATOM 3456 C CE3 . TRP A 1 433 ? 52.088 121.450 8.763 1.00 45.87 ? 433 TRP A CE3 1 ATOM 3457 C CZ2 . TRP A 1 433 ? 51.752 123.566 10.644 1.00 43.99 ? 433 TRP A CZ2 1 ATOM 3458 C CZ3 . TRP A 1 433 ? 53.128 121.842 9.614 1.00 43.54 ? 433 TRP A CZ3 1 ATOM 3459 C CH2 . TRP A 1 433 ? 52.951 122.887 10.546 1.00 44.33 ? 433 TRP A CH2 1 ATOM 3460 N N . MET A 1 434 ? 49.754 118.909 9.607 1.00 42.99 ? 434 MET A N 1 ATOM 3461 C CA . MET A 1 434 ? 50.737 118.345 10.540 1.00 42.39 ? 434 MET A CA 1 ATOM 3462 C C . MET A 1 434 ? 50.777 116.820 10.484 1.00 40.52 ? 434 MET A C 1 ATOM 3463 O O . MET A 1 434 ? 51.718 116.214 10.955 1.00 41.62 ? 434 MET A O 1 ATOM 3464 C CB . MET A 1 434 ? 50.521 118.838 11.969 1.00 41.66 ? 434 MET A CB 1 ATOM 3465 C CG . MET A 1 434 ? 50.612 120.356 12.115 1.00 43.62 ? 434 MET A CG 1 ATOM 3466 S SD . MET A 1 434 ? 50.755 120.800 13.835 1.00 43.42 ? 434 MET A SD 1 ATOM 3467 C CE . MET A 1 434 ? 51.171 122.502 13.738 1.00 49.18 ? 434 MET A CE 1 ATOM 3468 N N . GLY A 1 435 ? 49.761 116.217 9.903 1.00 39.19 ? 435 GLY A N 1 ATOM 3469 C CA . GLY A 1 435 ? 49.744 114.790 9.639 1.00 37.46 ? 435 GLY A CA 1 ATOM 3470 C C . GLY A 1 435 ? 49.889 113.875 10.838 1.00 37.13 ? 435 GLY A C 1 ATOM 3471 O O . GLY A 1 435 ? 49.219 114.092 11.862 1.00 35.56 ? 435 GLY A O 1 ATOM 3472 N N . VAL A 1 436 ? 50.750 112.847 10.694 1.00 36.19 ? 436 VAL A N 1 ATOM 3473 C CA . VAL A 1 436 ? 50.935 111.784 11.695 1.00 35.80 ? 436 VAL A CA 1 ATOM 3474 C C . VAL A 1 436 ? 52.055 112.191 12.642 1.00 36.41 ? 436 VAL A C 1 ATOM 3475 O O . VAL A 1 436 ? 53.250 111.847 12.455 1.00 37.01 ? 436 VAL A O 1 ATOM 3476 C CB . VAL A 1 436 ? 51.251 110.377 11.035 1.00 36.19 ? 436 VAL A CB 1 ATOM 3477 C CG1 . VAL A 1 436 ? 51.267 109.238 12.089 1.00 33.68 ? 436 VAL A CG1 1 ATOM 3478 C CG2 . VAL A 1 436 ? 50.273 110.077 9.881 1.00 34.30 ? 436 VAL A CG2 1 ATOM 3479 N N . MET A 1 437 ? 51.656 112.895 13.685 1.00 35.17 ? 437 MET A N 1 ATOM 3480 C CA . MET A 1 437 ? 52.582 113.637 14.487 1.00 34.54 ? 437 MET A CA 1 ATOM 3481 C C . MET A 1 437 ? 53.325 112.801 15.492 1.00 34.41 ? 437 MET A C 1 ATOM 3482 O O . MET A 1 437 ? 52.851 111.732 15.936 1.00 32.88 ? 437 MET A O 1 ATOM 3483 C CB . MET A 1 437 ? 51.843 114.757 15.240 1.00 35.16 ? 437 MET A CB 1 ATOM 3484 C CG . MET A 1 437 ? 51.414 115.904 14.353 1.00 36.40 ? 437 MET A CG 1 ATOM 3485 S SD . MET A 1 437 ? 50.282 117.024 15.253 1.00 38.31 ? 437 MET A SD 1 ATOM 3486 C CE . MET A 1 437 ? 51.369 117.734 16.506 1.00 31.03 ? 437 MET A CE 1 ATOM 3487 N N . HIS A 1 438 ? 54.503 113.331 15.839 1.00 34.35 ? 438 HIS A N 1 ATOM 3488 C CA . HIS A 1 438 ? 55.271 112.929 17.001 1.00 34.74 ? 438 HIS A CA 1 ATOM 3489 C C . HIS A 1 438 ? 54.393 112.822 18.242 1.00 35.26 ? 438 HIS A C 1 ATOM 3490 O O . HIS A 1 438 ? 53.694 113.763 18.542 1.00 34.93 ? 438 HIS A O 1 ATOM 3491 C CB . HIS A 1 438 ? 56.341 114.012 17.240 1.00 34.55 ? 438 HIS A CB 1 ATOM 3492 C CG . HIS A 1 438 ? 57.325 113.666 18.310 1.00 33.57 ? 438 HIS A CG 1 ATOM 3493 N ND1 . HIS A 1 438 ? 58.276 112.690 18.149 1.00 33.54 ? 438 HIS A ND1 1 ATOM 3494 C CD2 . HIS A 1 438 ? 57.527 114.192 19.542 1.00 33.77 ? 438 HIS A CD2 1 ATOM 3495 C CE1 . HIS A 1 438 ? 59.020 112.619 19.240 1.00 34.19 ? 438 HIS A CE1 1 ATOM 3496 N NE2 . HIS A 1 438 ? 58.584 113.522 20.102 1.00 33.79 ? 438 HIS A NE2 1 ATOM 3497 N N . GLY A 1 439 ? 54.416 111.677 18.940 1.00 35.85 ? 439 GLY A N 1 ATOM 3498 C CA . GLY A 1 439 ? 53.717 111.511 20.239 1.00 34.41 ? 439 GLY A CA 1 ATOM 3499 C C . GLY A 1 439 ? 52.358 110.874 20.039 1.00 35.22 ? 439 GLY A C 1 ATOM 3500 O O . GLY A 1 439 ? 51.710 110.445 20.991 1.00 35.22 ? 439 GLY A O 1 ATOM 3501 N N . TYR A 1 440 ? 51.889 110.799 18.799 1.00 34.32 ? 440 TYR A N 1 ATOM 3502 C CA . TYR A 1 440 ? 50.475 110.406 18.606 1.00 34.17 ? 440 TYR A CA 1 ATOM 3503 C C . TYR A 1 440 ? 50.246 108.925 18.243 1.00 34.48 ? 440 TYR A C 1 ATOM 3504 O O . TYR A 1 440 ? 49.134 108.533 17.882 1.00 36.29 ? 440 TYR A O 1 ATOM 3505 C CB . TYR A 1 440 ? 49.745 111.431 17.677 1.00 33.86 ? 440 TYR A CB 1 ATOM 3506 C CG . TYR A 1 440 ? 49.532 112.731 18.464 1.00 34.27 ? 440 TYR A CG 1 ATOM 3507 C CD1 . TYR A 1 440 ? 50.469 113.757 18.446 1.00 32.60 ? 440 TYR A CD1 1 ATOM 3508 C CD2 . TYR A 1 440 ? 48.446 112.854 19.341 1.00 34.68 ? 440 TYR A CD2 1 ATOM 3509 C CE1 . TYR A 1 440 ? 50.287 114.954 19.223 1.00 35.42 ? 440 TYR A CE1 1 ATOM 3510 C CE2 . TYR A 1 440 ? 48.273 114.009 20.144 1.00 34.32 ? 440 TYR A CE2 1 ATOM 3511 C CZ . TYR A 1 440 ? 49.160 115.047 20.063 1.00 36.15 ? 440 TYR A CZ 1 ATOM 3512 O OH . TYR A 1 440 ? 48.926 116.130 20.880 1.00 39.12 ? 440 TYR A OH 1 ATOM 3513 N N . GLU A 1 441 ? 51.281 108.099 18.348 1.00 33.55 ? 441 GLU A N 1 ATOM 3514 C CA . GLU A 1 441 ? 51.089 106.646 18.374 1.00 33.07 ? 441 GLU A CA 1 ATOM 3515 C C . GLU A 1 441 ? 50.838 106.152 19.816 1.00 32.95 ? 441 GLU A C 1 ATOM 3516 O O . GLU A 1 441 ? 50.347 105.026 20.039 1.00 32.89 ? 441 GLU A O 1 ATOM 3517 C CB . GLU A 1 441 ? 52.326 105.952 17.774 1.00 33.79 ? 441 GLU A CB 1 ATOM 3518 C CG . GLU A 1 441 ? 53.433 105.621 18.760 1.00 33.32 ? 441 GLU A CG 1 ATOM 3519 C CD . GLU A 1 441 ? 54.172 106.842 19.322 1.00 36.18 ? 441 GLU A CD 1 ATOM 3520 O OE1 . GLU A 1 441 ? 53.973 107.983 18.810 1.00 33.57 ? 441 GLU A OE1 1 ATOM 3521 O OE2 . GLU A 1 441 ? 54.984 106.626 20.272 1.00 33.44 ? 441 GLU A OE2 1 ATOM 3522 N N . ILE A 1 442 ? 51.193 106.995 20.790 1.00 32.39 ? 442 ILE A N 1 ATOM 3523 C CA . ILE A 1 442 ? 51.264 106.574 22.181 1.00 33.27 ? 442 ILE A CA 1 ATOM 3524 C C . ILE A 1 442 ? 49.896 106.089 22.596 1.00 33.97 ? 442 ILE A C 1 ATOM 3525 O O . ILE A 1 442 ? 49.767 105.006 23.158 1.00 34.55 ? 442 ILE A O 1 ATOM 3526 C CB . ILE A 1 442 ? 51.745 107.711 23.104 1.00 33.37 ? 442 ILE A CB 1 ATOM 3527 C CG1 . ILE A 1 442 ? 53.186 108.103 22.744 1.00 32.57 ? 442 ILE A CG1 1 ATOM 3528 C CG2 . ILE A 1 442 ? 51.678 107.272 24.594 1.00 33.49 ? 442 ILE A CG2 1 ATOM 3529 C CD1 . ILE A 1 442 ? 53.709 109.321 23.519 1.00 29.39 ? 442 ILE A CD1 1 ATOM 3530 N N . GLU A 1 443 ? 48.858 106.848 22.239 1.00 35.40 ? 443 GLU A N 1 ATOM 3531 C CA . GLU A 1 443 ? 47.503 106.479 22.676 1.00 36.08 ? 443 GLU A CA 1 ATOM 3532 C C . GLU A 1 443 ? 47.042 105.148 22.052 1.00 36.09 ? 443 GLU A C 1 ATOM 3533 O O . GLU A 1 443 ? 46.239 104.467 22.654 1.00 35.39 ? 443 GLU A O 1 ATOM 3534 C CB . GLU A 1 443 ? 46.507 107.597 22.419 1.00 35.57 ? 443 GLU A CB 1 ATOM 3535 C CG . GLU A 1 443 ? 46.307 107.907 20.952 1.00 38.44 ? 443 GLU A CG 1 ATOM 3536 C CD . GLU A 1 443 ? 45.824 109.332 20.739 1.00 42.77 ? 443 GLU A CD 1 ATOM 3537 O OE1 . GLU A 1 443 ? 46.616 110.293 20.953 1.00 38.61 ? 443 GLU A OE1 1 ATOM 3538 O OE2 . GLU A 1 443 ? 44.648 109.478 20.323 1.00 45.45 ? 443 GLU A OE2 1 ATOM 3539 N N . PHE A 1 444 ? 47.538 104.797 20.852 1.00 36.15 ? 444 PHE A N 1 ATOM 3540 C CA . PHE A 1 444 ? 47.286 103.456 20.261 1.00 35.62 ? 444 PHE A CA 1 ATOM 3541 C C . PHE A 1 444 ? 48.002 102.323 21.010 1.00 35.82 ? 444 PHE A C 1 ATOM 3542 O O . PHE A 1 444 ? 47.435 101.231 21.229 1.00 36.69 ? 444 PHE A O 1 ATOM 3543 C CB . PHE A 1 444 ? 47.631 103.437 18.763 1.00 35.17 ? 444 PHE A CB 1 ATOM 3544 C CG . PHE A 1 444 ? 46.658 104.207 17.973 1.00 34.59 ? 444 PHE A CG 1 ATOM 3545 C CD1 . PHE A 1 444 ? 46.701 105.596 17.970 1.00 32.96 ? 444 PHE A CD1 1 ATOM 3546 C CD2 . PHE A 1 444 ? 45.611 103.556 17.332 1.00 37.70 ? 444 PHE A CD2 1 ATOM 3547 C CE1 . PHE A 1 444 ? 45.713 106.333 17.303 1.00 34.50 ? 444 PHE A CE1 1 ATOM 3548 C CE2 . PHE A 1 444 ? 44.614 104.281 16.670 1.00 34.52 ? 444 PHE A CE2 1 ATOM 3549 C CZ . PHE A 1 444 ? 44.677 105.665 16.646 1.00 35.05 ? 444 PHE A CZ 1 ATOM 3550 N N . VAL A 1 445 ? 49.246 102.580 21.392 1.00 34.57 ? 445 VAL A N 1 ATOM 3551 C CA . VAL A 1 445 ? 50.016 101.618 22.164 1.00 33.57 ? 445 VAL A CA 1 ATOM 3552 C C . VAL A 1 445 ? 49.353 101.315 23.520 1.00 34.46 ? 445 VAL A C 1 ATOM 3553 O O . VAL A 1 445 ? 49.320 100.149 23.947 1.00 34.11 ? 445 VAL A O 1 ATOM 3554 C CB . VAL A 1 445 ? 51.493 102.125 22.356 1.00 34.18 ? 445 VAL A CB 1 ATOM 3555 C CG1 . VAL A 1 445 ? 52.235 101.341 23.479 1.00 30.68 ? 445 VAL A CG1 1 ATOM 3556 C CG2 . VAL A 1 445 ? 52.244 102.101 20.986 1.00 30.10 ? 445 VAL A CG2 1 ATOM 3557 N N . PHE A 1 446 ? 48.836 102.354 24.189 1.00 34.30 ? 446 PHE A N 1 ATOM 3558 C CA . PHE A 1 446 ? 48.252 102.164 25.521 1.00 34.69 ? 446 PHE A CA 1 ATOM 3559 C C . PHE A 1 446 ? 46.776 101.701 25.460 1.00 36.38 ? 446 PHE A C 1 ATOM 3560 O O . PHE A 1 446 ? 46.181 101.390 26.502 1.00 36.74 ? 446 PHE A O 1 ATOM 3561 C CB . PHE A 1 446 ? 48.439 103.414 26.405 1.00 33.51 ? 446 PHE A CB 1 ATOM 3562 C CG . PHE A 1 446 ? 49.785 103.497 27.091 1.00 31.04 ? 446 PHE A CG 1 ATOM 3563 C CD1 . PHE A 1 446 ? 50.886 104.075 26.432 1.00 30.94 ? 446 PHE A CD1 1 ATOM 3564 C CD2 . PHE A 1 446 ? 49.950 103.016 28.367 1.00 30.57 ? 446 PHE A CD2 1 ATOM 3565 C CE1 . PHE A 1 446 ? 52.136 104.187 27.059 1.00 31.89 ? 446 PHE A CE1 1 ATOM 3566 C CE2 . PHE A 1 446 ? 51.184 103.106 29.034 1.00 32.85 ? 446 PHE A CE2 1 ATOM 3567 C CZ . PHE A 1 446 ? 52.300 103.709 28.382 1.00 29.68 ? 446 PHE A CZ 1 ATOM 3568 N N . GLY A 1 447 ? 46.194 101.658 24.250 1.00 37.74 ? 447 GLY A N 1 ATOM 3569 C CA . GLY A 1 447 ? 44.877 101.019 24.059 1.00 38.65 ? 447 GLY A CA 1 ATOM 3570 C C . GLY A 1 447 ? 43.712 101.961 24.284 1.00 40.00 ? 447 GLY A C 1 ATOM 3571 O O . GLY A 1 447 ? 42.585 101.545 24.514 1.00 39.29 ? 447 GLY A O 1 ATOM 3572 N N . LEU A 1 448 ? 43.975 103.258 24.202 1.00 40.81 ? 448 LEU A N 1 ATOM 3573 C CA . LEU A 1 448 ? 42.914 104.215 24.453 1.00 42.22 ? 448 LEU A CA 1 ATOM 3574 C C . LEU A 1 448 ? 41.723 104.016 23.503 1.00 43.73 ? 448 LEU A C 1 ATOM 3575 O O . LEU A 1 448 ? 40.573 104.099 23.960 1.00 44.72 ? 448 LEU A O 1 ATOM 3576 C CB . LEU A 1 448 ? 43.435 105.657 24.465 1.00 41.19 ? 448 LEU A CB 1 ATOM 3577 C CG . LEU A 1 448 ? 43.872 106.243 25.823 1.00 40.68 ? 448 LEU A CG 1 ATOM 3578 C CD1 . LEU A 1 448 ? 45.013 105.461 26.489 1.00 36.50 ? 448 LEU A CD1 1 ATOM 3579 C CD2 . LEU A 1 448 ? 44.238 107.733 25.598 1.00 40.25 ? 448 LEU A CD2 1 ATOM 3580 N N . PRO A 1 449 ? 41.980 103.745 22.211 1.00 44.54 ? 449 PRO A N 1 ATOM 3581 C CA . PRO A 1 449 ? 40.894 103.410 21.264 1.00 45.45 ? 449 PRO A CA 1 ATOM 3582 C C . PRO A 1 449 ? 40.118 102.126 21.534 1.00 46.02 ? 449 PRO A C 1 ATOM 3583 O O . PRO A 1 449 ? 39.143 101.882 20.861 1.00 46.25 ? 449 PRO A O 1 ATOM 3584 C CB . PRO A 1 449 ? 41.603 103.325 19.904 1.00 44.36 ? 449 PRO A CB 1 ATOM 3585 C CG . PRO A 1 449 ? 42.861 104.121 20.113 1.00 45.22 ? 449 PRO A CG 1 ATOM 3586 C CD . PRO A 1 449 ? 43.285 103.811 21.523 1.00 43.20 ? 449 PRO A CD 1 ATOM 3587 N N . LEU A 1 450 ? 40.544 101.309 22.478 1.00 47.91 ? 450 LEU A N 1 ATOM 3588 C CA . LEU A 1 450 ? 39.752 100.141 22.872 1.00 49.72 ? 450 LEU A CA 1 ATOM 3589 C C . LEU A 1 450 ? 38.525 100.560 23.706 1.00 52.28 ? 450 LEU A C 1 ATOM 3590 O O . LEU A 1 450 ? 37.567 99.795 23.874 1.00 52.17 ? 450 LEU A O 1 ATOM 3591 C CB . LEU A 1 450 ? 40.597 99.097 23.607 1.00 48.06 ? 450 LEU A CB 1 ATOM 3592 C CG . LEU A 1 450 ? 41.856 98.618 22.862 1.00 48.19 ? 450 LEU A CG 1 ATOM 3593 C CD1 . LEU A 1 450 ? 42.689 97.642 23.682 1.00 44.80 ? 450 LEU A CD1 1 ATOM 3594 C CD2 . LEU A 1 450 ? 41.542 98.037 21.441 1.00 47.94 ? 450 LEU A CD2 1 ATOM 3595 N N . GLU A 1 451 ? 38.568 101.784 24.222 1.00 55.46 ? 451 GLU A N 1 ATOM 3596 C CA . GLU A 1 451 ? 37.452 102.351 24.954 1.00 57.92 ? 451 GLU A CA 1 ATOM 3597 C C . GLU A 1 451 ? 36.475 102.958 23.955 1.00 58.93 ? 451 GLU A C 1 ATOM 3598 O O . GLU A 1 451 ? 36.734 104.004 23.324 1.00 58.39 ? 451 GLU A O 1 ATOM 3599 C CB . GLU A 1 451 ? 37.927 103.376 25.972 1.00 58.78 ? 451 GLU A CB 1 ATOM 3600 C CG . GLU A 1 451 ? 36.799 104.114 26.681 1.00 62.57 ? 451 GLU A CG 1 ATOM 3601 C CD . GLU A 1 451 ? 36.128 103.250 27.738 1.00 67.10 ? 451 GLU A CD 1 ATOM 3602 O OE1 . GLU A 1 451 ? 35.118 102.563 27.414 1.00 69.64 ? 451 GLU A OE1 1 ATOM 3603 O OE2 . GLU A 1 451 ? 36.634 103.238 28.888 1.00 69.71 ? 451 GLU A OE2 1 ATOM 3604 N N . ARG A 1 452 ? 35.356 102.257 23.815 1.00 60.83 ? 452 ARG A N 1 ATOM 3605 C CA . ARG A 1 452 ? 34.285 102.605 22.881 1.00 63.38 ? 452 ARG A CA 1 ATOM 3606 C C . ARG A 1 452 ? 33.587 103.951 23.155 1.00 63.83 ? 452 ARG A C 1 ATOM 3607 O O . ARG A 1 452 ? 33.057 104.570 22.239 1.00 63.54 ? 452 ARG A O 1 ATOM 3608 C CB . ARG A 1 452 ? 33.265 101.465 22.824 1.00 63.54 ? 452 ARG A CB 1 ATOM 3609 C CG . ARG A 1 452 ? 33.583 100.471 21.747 1.00 67.41 ? 452 ARG A CG 1 ATOM 3610 C CD . ARG A 1 452 ? 32.970 100.852 20.410 1.00 73.94 ? 452 ARG A CD 1 ATOM 3611 N NE . ARG A 1 452 ? 33.831 100.469 19.291 1.00 78.34 ? 452 ARG A NE 1 ATOM 3612 C CZ . ARG A 1 452 ? 34.436 101.316 18.452 1.00 79.19 ? 452 ARG A CZ 1 ATOM 3613 N NH1 . ARG A 1 452 ? 34.289 102.637 18.563 1.00 79.66 ? 452 ARG A NH1 1 ATOM 3614 N NH2 . ARG A 1 452 ? 35.191 100.821 17.484 1.00 78.62 ? 452 ARG A NH2 1 ATOM 3615 N N . ARG A 1 453 ? 33.597 104.398 24.405 1.00 64.86 ? 453 ARG A N 1 ATOM 3616 C CA . ARG A 1 453 ? 32.965 105.665 24.747 1.00 66.50 ? 453 ARG A CA 1 ATOM 3617 C C . ARG A 1 453 ? 33.762 106.836 24.173 1.00 66.73 ? 453 ARG A C 1 ATOM 3618 O O . ARG A 1 453 ? 33.215 107.939 23.981 1.00 67.51 ? 453 ARG A O 1 ATOM 3619 C CB . ARG A 1 453 ? 32.821 105.825 26.276 1.00 67.07 ? 453 ARG A CB 1 ATOM 3620 C CG . ARG A 1 453 ? 32.606 104.519 27.092 1.00 70.09 ? 453 ARG A CG 1 ATOM 3621 C CD . ARG A 1 453 ? 31.418 103.641 26.686 1.00 75.04 ? 453 ARG A CD 1 ATOM 3622 N NE . ARG A 1 453 ? 30.140 104.178 27.150 1.00 79.47 ? 453 ARG A NE 1 ATOM 3623 C CZ . ARG A 1 453 ? 29.295 104.911 26.410 1.00 81.93 ? 453 ARG A CZ 1 ATOM 3624 N NH1 . ARG A 1 453 ? 29.569 105.212 25.139 1.00 82.00 ? 453 ARG A NH1 1 ATOM 3625 N NH2 . ARG A 1 453 ? 28.159 105.344 26.949 1.00 82.73 ? 453 ARG A NH2 1 ATOM 3626 N N . ASP A 1 454 ? 35.038 106.582 23.865 1.00 65.92 ? 454 ASP A N 1 ATOM 3627 C CA . ASP A 1 454 ? 36.005 107.646 23.662 1.00 65.59 ? 454 ASP A CA 1 ATOM 3628 C C . ASP A 1 454 ? 35.995 108.392 22.321 1.00 64.11 ? 454 ASP A C 1 ATOM 3629 O O . ASP A 1 454 ? 36.828 109.282 22.123 1.00 64.96 ? 454 ASP A O 1 ATOM 3630 C CB . ASP A 1 454 ? 37.412 107.135 23.961 1.00 66.57 ? 454 ASP A CB 1 ATOM 3631 C CG . ASP A 1 454 ? 38.120 107.971 25.014 1.00 69.97 ? 454 ASP A CG 1 ATOM 3632 O OD1 . ASP A 1 454 ? 37.428 108.419 25.980 1.00 73.09 ? 454 ASP A OD1 1 ATOM 3633 O OD2 . ASP A 1 454 ? 39.366 108.206 24.977 1.00 73.09 ? 454 ASP A OD2 1 ATOM 3634 N N . GLN A 1 455 ? 35.081 108.041 21.415 1.00 61.87 ? 455 GLN A N 1 ATOM 3635 C CA . GLN A 1 455 ? 34.884 108.784 20.149 1.00 59.52 ? 455 GLN A CA 1 ATOM 3636 C C . GLN A 1 455 ? 35.828 108.397 18.969 1.00 58.00 ? 455 GLN A C 1 ATOM 3637 O O . GLN A 1 455 ? 35.723 109.003 17.907 1.00 58.40 ? 455 GLN A O 1 ATOM 3638 C CB . GLN A 1 455 ? 34.938 110.311 20.375 0.30 59.84 ? 455 GLN A CB 1 ATOM 3639 C CG . GLN A 1 455 ? 33.979 110.865 21.435 0.30 60.05 ? 455 GLN A CG 1 ATOM 3640 C CD . GLN A 1 455 ? 32.722 111.459 20.834 0.30 60.61 ? 455 GLN A CD 1 ATOM 3641 O OE1 . GLN A 1 455 ? 32.574 112.686 20.795 0.30 60.77 ? 455 GLN A OE1 1 ATOM 3642 N NE2 . GLN A 1 455 ? 31.816 110.599 20.355 0.30 60.46 ? 455 GLN A NE2 1 ATOM 3643 N N . TYR A 1 456 ? 36.740 107.428 19.146 1.00 54.90 ? 456 TYR A N 1 ATOM 3644 C CA . TYR A 1 456 ? 37.556 106.883 18.027 1.00 51.13 ? 456 TYR A CA 1 ATOM 3645 C C . TYR A 1 456 ? 36.714 106.014 17.092 1.00 50.75 ? 456 TYR A C 1 ATOM 3646 O O . TYR A 1 456 ? 35.740 105.390 17.541 1.00 49.77 ? 456 TYR A O 1 ATOM 3647 C CB . TYR A 1 456 ? 38.695 105.984 18.558 1.00 49.89 ? 456 TYR A CB 1 ATOM 3648 C CG . TYR A 1 456 ? 39.755 106.658 19.425 1.00 45.55 ? 456 TYR A CG 1 ATOM 3649 C CD1 . TYR A 1 456 ? 39.681 106.641 20.818 1.00 42.87 ? 456 TYR A CD1 1 ATOM 3650 C CD2 . TYR A 1 456 ? 40.837 107.306 18.836 1.00 43.45 ? 456 TYR A CD2 1 ATOM 3651 C CE1 . TYR A 1 456 ? 40.688 107.255 21.619 1.00 41.48 ? 456 TYR A CE1 1 ATOM 3652 C CE2 . TYR A 1 456 ? 41.830 107.916 19.608 1.00 42.55 ? 456 TYR A CE2 1 ATOM 3653 C CZ . TYR A 1 456 ? 41.762 107.886 20.979 1.00 42.16 ? 456 TYR A CZ 1 ATOM 3654 O OH . TYR A 1 456 ? 42.775 108.488 21.679 1.00 41.88 ? 456 TYR A OH 1 ATOM 3655 N N . THR A 1 457 ? 37.134 105.920 15.817 1.00 49.14 ? 457 THR A N 1 ATOM 3656 C CA . THR A 1 457 ? 36.500 105.040 14.848 1.00 47.89 ? 457 THR A CA 1 ATOM 3657 C C . THR A 1 457 ? 36.744 103.562 15.143 1.00 48.42 ? 457 THR A C 1 ATOM 3658 O O . THR A 1 457 ? 37.633 103.189 15.925 1.00 48.11 ? 457 THR A O 1 ATOM 3659 C CB . THR A 1 457 ? 36.933 105.329 13.371 1.00 47.66 ? 457 THR A CB 1 ATOM 3660 O OG1 . THR A 1 457 ? 38.283 104.912 13.180 1.00 46.92 ? 457 THR A OG1 1 ATOM 3661 C CG2 . THR A 1 457 ? 36.926 106.831 13.021 1.00 45.66 ? 457 THR A CG2 1 ATOM 3662 N N . LYS A 1 458 ? 35.952 102.723 14.476 1.00 48.12 ? 458 LYS A N 1 ATOM 3663 C CA . LYS A 1 458 ? 36.068 101.273 14.588 1.00 48.23 ? 458 LYS A CA 1 ATOM 3664 C C . LYS A 1 458 ? 37.402 100.768 13.999 1.00 47.09 ? 458 LYS A C 1 ATOM 3665 O O . LYS A 1 458 ? 38.019 99.847 14.545 1.00 45.76 ? 458 LYS A O 1 ATOM 3666 C CB . LYS A 1 458 ? 34.855 100.570 13.904 1.00 48.99 ? 458 LYS A CB 1 ATOM 3667 C CG . LYS A 1 458 ? 34.886 99.053 14.000 1.00 52.03 ? 458 LYS A CG 1 ATOM 3668 C CD . LYS A 1 458 ? 34.170 98.600 15.255 1.00 56.22 ? 458 LYS A CD 1 ATOM 3669 C CE . LYS A 1 458 ? 34.732 97.276 15.783 1.00 59.67 ? 458 LYS A CE 1 ATOM 3670 N NZ . LYS A 1 458 ? 34.165 97.018 17.166 1.00 60.44 ? 458 LYS A NZ 1 ATOM 3671 N N . ALA A 1 459 ? 37.827 101.364 12.884 1.00 45.65 ? 459 ALA A N 1 ATOM 3672 C CA . ALA A 1 459 ? 39.084 100.973 12.303 1.00 45.75 ? 459 ALA A CA 1 ATOM 3673 C C . ALA A 1 459 ? 40.229 101.248 13.295 1.00 45.56 ? 459 ALA A C 1 ATOM 3674 O O . ALA A 1 459 ? 41.203 100.503 13.317 1.00 46.01 ? 459 ALA A O 1 ATOM 3675 C CB . ALA A 1 459 ? 39.315 101.658 10.932 1.00 45.07 ? 459 ALA A CB 1 ATOM 3676 N N . GLU A 1 460 ? 40.068 102.280 14.124 1.00 44.91 ? 460 GLU A N 1 ATOM 3677 C CA . GLU A 1 460 ? 41.069 102.670 15.137 1.00 44.71 ? 460 GLU A CA 1 ATOM 3678 C C . GLU A 1 460 ? 41.094 101.727 16.335 1.00 44.45 ? 460 GLU A C 1 ATOM 3679 O O . GLU A 1 460 ? 42.160 101.350 16.829 1.00 43.83 ? 460 GLU A O 1 ATOM 3680 C CB . GLU A 1 460 ? 40.860 104.138 15.576 1.00 44.45 ? 460 GLU A CB 1 ATOM 3681 C CG . GLU A 1 460 ? 41.283 105.129 14.496 1.00 44.30 ? 460 GLU A CG 1 ATOM 3682 C CD . GLU A 1 460 ? 41.061 106.602 14.846 1.00 46.99 ? 460 GLU A CD 1 ATOM 3683 O OE1 . GLU A 1 460 ? 40.114 106.927 15.586 1.00 48.07 ? 460 GLU A OE1 1 ATOM 3684 O OE2 . GLU A 1 460 ? 41.817 107.467 14.329 1.00 46.32 ? 460 GLU A OE2 1 ATOM 3685 N N . GLU A 1 461 ? 39.918 101.315 16.802 1.00 44.97 ? 461 GLU A N 1 ATOM 3686 C CA . GLU A 1 461 ? 39.839 100.233 17.782 1.00 44.63 ? 461 GLU A CA 1 ATOM 3687 C C . GLU A 1 461 ? 40.611 99.008 17.308 1.00 43.64 ? 461 GLU A C 1 ATOM 3688 O O . GLU A 1 461 ? 41.418 98.440 18.032 1.00 44.26 ? 461 GLU A O 1 ATOM 3689 C CB . GLU A 1 461 ? 38.379 99.846 18.063 1.00 44.92 ? 461 GLU A CB 1 ATOM 3690 C CG . GLU A 1 461 ? 38.259 98.713 19.092 1.00 48.09 ? 461 GLU A CG 1 ATOM 3691 C CD . GLU A 1 461 ? 36.853 98.112 19.197 1.00 53.60 ? 461 GLU A CD 1 ATOM 3692 O OE1 . GLU A 1 461 ? 36.727 96.876 19.135 1.00 55.88 ? 461 GLU A OE1 1 ATOM 3693 O OE2 . GLU A 1 461 ? 35.871 98.864 19.333 1.00 56.90 ? 461 GLU A OE2 1 ATOM 3694 N N . ILE A 1 462 ? 40.348 98.579 16.088 1.00 43.74 ? 462 ILE A N 1 ATOM 3695 C CA . ILE A 1 462 ? 41.016 97.382 15.574 1.00 43.77 ? 462 ILE A CA 1 ATOM 3696 C C . ILE A 1 462 ? 42.563 97.593 15.469 1.00 42.02 ? 462 ILE A C 1 ATOM 3697 O O . ILE A 1 462 ? 43.346 96.716 15.864 1.00 42.46 ? 462 ILE A O 1 ATOM 3698 C CB . ILE A 1 462 ? 40.359 96.934 14.210 1.00 44.87 ? 462 ILE A CB 1 ATOM 3699 C CG1 . ILE A 1 462 ? 38.859 96.654 14.402 1.00 48.21 ? 462 ILE A CG1 1 ATOM 3700 C CG2 . ILE A 1 462 ? 40.996 95.636 13.678 1.00 44.83 ? 462 ILE A CG2 1 ATOM 3701 C CD1 . ILE A 1 462 ? 38.570 95.288 15.154 1.00 49.21 ? 462 ILE A CD1 1 ATOM 3702 N N . LEU A 1 463 ? 42.992 98.765 14.999 1.00 39.97 ? 463 LEU A N 1 ATOM 3703 C CA . LEU A 1 463 ? 44.439 99.067 14.903 1.00 39.54 ? 463 LEU A CA 1 ATOM 3704 C C . LEU A 1 463 ? 45.083 99.033 16.291 1.00 38.23 ? 463 LEU A C 1 ATOM 3705 O O . LEU A 1 463 ? 46.114 98.401 16.498 1.00 37.95 ? 463 LEU A O 1 ATOM 3706 C CB . LEU A 1 463 ? 44.687 100.422 14.212 1.00 38.97 ? 463 LEU A CB 1 ATOM 3707 C CG . LEU A 1 463 ? 46.153 100.913 14.168 1.00 39.73 ? 463 LEU A CG 1 ATOM 3708 C CD1 . LEU A 1 463 ? 47.152 99.929 13.448 1.00 40.39 ? 463 LEU A CD1 1 ATOM 3709 C CD2 . LEU A 1 463 ? 46.162 102.257 13.515 1.00 37.49 ? 463 LEU A CD2 1 ATOM 3710 N N . SER A 1 464 ? 44.425 99.663 17.254 1.00 37.87 ? 464 SER A N 1 ATOM 3711 C CA . SER A 1 464 ? 44.935 99.689 18.616 1.00 38.26 ? 464 SER A CA 1 ATOM 3712 C C . SER A 1 464 ? 45.006 98.265 19.184 1.00 38.58 ? 464 SER A C 1 ATOM 3713 O O . SER A 1 464 ? 46.001 97.876 19.784 1.00 39.65 ? 464 SER A O 1 ATOM 3714 C CB . SER A 1 464 ? 44.102 100.618 19.513 1.00 37.05 ? 464 SER A CB 1 ATOM 3715 O OG . SER A 1 464 ? 44.650 100.682 20.823 1.00 35.01 ? 464 SER A OG 1 ATOM 3716 N N . ARG A 1 465 ? 43.965 97.484 18.955 1.00 38.84 ? 465 ARG A N 1 ATOM 3717 C CA . ARG A 1 465 ? 43.905 96.105 19.464 1.00 39.27 ? 465 ARG A CA 1 ATOM 3718 C C . ARG A 1 465 ? 45.115 95.295 18.990 1.00 38.96 ? 465 ARG A C 1 ATOM 3719 O O . ARG A 1 465 ? 45.782 94.564 19.756 1.00 40.19 ? 465 ARG A O 1 ATOM 3720 C CB . ARG A 1 465 ? 42.559 95.429 19.010 1.00 38.80 ? 465 ARG A CB 1 ATOM 3721 C CG . ARG A 1 465 ? 42.328 94.019 19.592 1.00 40.23 ? 465 ARG A CG 1 ATOM 3722 C CD . ARG A 1 465 ? 42.230 94.036 21.141 1.00 43.23 ? 465 ARG A CD 1 ATOM 3723 N NE . ARG A 1 465 ? 42.483 92.742 21.790 1.00 46.86 ? 465 ARG A NE 1 ATOM 3724 C CZ . ARG A 1 465 ? 43.668 92.301 22.249 1.00 48.85 ? 465 ARG A CZ 1 ATOM 3725 N NH1 . ARG A 1 465 ? 44.818 93.024 22.126 1.00 45.33 ? 465 ARG A NH1 1 ATOM 3726 N NH2 . ARG A 1 465 ? 43.699 91.108 22.845 1.00 47.98 ? 465 ARG A NH2 1 ATOM 3727 N N . SER A 1 466 ? 45.388 95.410 17.707 1.00 38.35 ? 466 SER A N 1 ATOM 3728 C CA . SER A 1 466 ? 46.480 94.681 17.098 1.00 38.52 ? 466 SER A CA 1 ATOM 3729 C C . SER A 1 466 ? 47.905 95.081 17.610 1.00 37.62 ? 466 SER A C 1 ATOM 3730 O O . SER A 1 466 ? 48.764 94.199 17.900 1.00 38.42 ? 466 SER A O 1 ATOM 3731 C CB . SER A 1 466 ? 46.359 94.834 15.572 1.00 37.87 ? 466 SER A CB 1 ATOM 3732 O OG . SER A 1 466 ? 47.474 94.190 14.985 1.00 42.96 ? 466 SER A OG 1 ATOM 3733 N N . ILE A 1 467 ? 48.132 96.392 17.724 1.00 36.81 ? 467 ILE A N 1 ATOM 3734 C CA . ILE A 1 467 ? 49.380 97.004 18.244 1.00 35.40 ? 467 ILE A CA 1 ATOM 3735 C C . ILE A 1 467 ? 49.600 96.546 19.677 1.00 35.62 ? 467 ILE A C 1 ATOM 3736 O O . ILE A 1 467 ? 50.691 96.150 20.071 1.00 34.82 ? 467 ILE A O 1 ATOM 3737 C CB . ILE A 1 467 ? 49.279 98.592 18.174 1.00 36.12 ? 467 ILE A CB 1 ATOM 3738 C CG1 . ILE A 1 467 ? 49.447 99.082 16.714 1.00 36.08 ? 467 ILE A CG1 1 ATOM 3739 C CG2 . ILE A 1 467 ? 50.294 99.306 19.179 1.00 34.69 ? 467 ILE A CG2 1 ATOM 3740 C CD1 . ILE A 1 467 ? 49.219 100.640 16.466 1.00 29.46 ? 467 ILE A CD1 1 ATOM 3741 N N . VAL A 1 468 ? 48.530 96.594 20.460 1.00 35.50 ? 468 VAL A N 1 ATOM 3742 C CA . VAL A 1 468 ? 48.591 96.173 21.863 1.00 34.81 ? 468 VAL A CA 1 ATOM 3743 C C . VAL A 1 468 ? 49.021 94.708 21.952 1.00 34.90 ? 468 VAL A C 1 ATOM 3744 O O . VAL A 1 468 ? 49.908 94.354 22.764 1.00 34.91 ? 468 VAL A O 1 ATOM 3745 C CB . VAL A 1 468 ? 47.187 96.405 22.544 1.00 35.19 ? 468 VAL A CB 1 ATOM 3746 C CG1 . VAL A 1 468 ? 47.007 95.520 23.769 1.00 33.04 ? 468 VAL A CG1 1 ATOM 3747 C CG2 . VAL A 1 468 ? 46.969 97.900 22.859 1.00 31.71 ? 468 VAL A CG2 1 ATOM 3748 N N . LYS A 1 469 ? 48.426 93.874 21.087 1.00 33.62 ? 469 LYS A N 1 ATOM 3749 C CA . LYS A 1 469 ? 48.806 92.457 20.990 1.00 33.45 ? 469 LYS A CA 1 ATOM 3750 C C . LYS A 1 469 ? 50.270 92.281 20.526 1.00 33.13 ? 469 LYS A C 1 ATOM 3751 O O . LYS A 1 469 ? 51.026 91.519 21.111 1.00 34.22 ? 469 LYS A O 1 ATOM 3752 C CB . LYS A 1 469 ? 47.836 91.710 20.039 1.00 33.18 ? 469 LYS A CB 1 ATOM 3753 C CG . LYS A 1 469 ? 48.137 90.237 19.819 1.00 33.60 ? 469 LYS A CG 1 ATOM 3754 C CD . LYS A 1 469 ? 48.194 89.470 21.151 1.00 37.10 ? 469 LYS A CD 1 ATOM 3755 C CE . LYS A 1 469 ? 46.793 89.186 21.742 1.00 38.17 ? 469 LYS A CE 1 ATOM 3756 N NZ . LYS A 1 469 ? 46.945 88.511 23.084 1.00 39.09 ? 469 LYS A NZ 1 ATOM 3757 N N . ARG A 1 470 ? 50.684 93.025 19.506 1.00 33.54 ? 470 ARG A N 1 ATOM 3758 C CA . ARG A 1 470 ? 52.091 92.928 19.032 1.00 33.69 ? 470 ARG A CA 1 ATOM 3759 C C . ARG A 1 470 ? 53.102 93.335 20.139 1.00 34.10 ? 470 ARG A C 1 ATOM 3760 O O . ARG A 1 470 ? 54.101 92.645 20.360 1.00 32.84 ? 470 ARG A O 1 ATOM 3761 C CB . ARG A 1 470 ? 52.310 93.742 17.752 1.00 32.96 ? 470 ARG A CB 1 ATOM 3762 C CG . ARG A 1 470 ? 51.575 93.202 16.522 1.00 31.86 ? 470 ARG A CG 1 ATOM 3763 C CD . ARG A 1 470 ? 51.795 94.044 15.277 1.00 33.43 ? 470 ARG A CD 1 ATOM 3764 N NE . ARG A 1 470 ? 51.057 93.615 14.063 1.00 35.19 ? 470 ARG A NE 1 ATOM 3765 C CZ . ARG A 1 470 ? 51.445 92.674 13.187 1.00 38.05 ? 470 ARG A CZ 1 ATOM 3766 N NH1 . ARG A 1 470 ? 50.693 92.421 12.106 1.00 40.13 ? 470 ARG A NH1 1 ATOM 3767 N NH2 . ARG A 1 470 ? 52.541 91.952 13.393 1.00 36.57 ? 470 ARG A NH2 1 ATOM 3768 N N . TRP A 1 471 ? 52.815 94.447 20.838 1.00 34.14 ? 471 TRP A N 1 ATOM 3769 C CA . TRP A 1 471 ? 53.686 94.930 21.918 1.00 33.32 ? 471 TRP A CA 1 ATOM 3770 C C . TRP A 1 471 ? 53.764 93.937 23.039 1.00 33.11 ? 471 TRP A C 1 ATOM 3771 O O . TRP A 1 471 ? 54.828 93.720 23.563 1.00 33.58 ? 471 TRP A O 1 ATOM 3772 C CB . TRP A 1 471 ? 53.208 96.309 22.445 1.00 32.69 ? 471 TRP A CB 1 ATOM 3773 C CG . TRP A 1 471 ? 53.871 97.593 21.813 1.00 31.87 ? 471 TRP A CG 1 ATOM 3774 C CD1 . TRP A 1 471 ? 54.415 98.681 22.503 1.00 31.06 ? 471 TRP A CD1 1 ATOM 3775 C CD2 . TRP A 1 471 ? 53.992 97.916 20.416 1.00 29.07 ? 471 TRP A CD2 1 ATOM 3776 N NE1 . TRP A 1 471 ? 54.869 99.627 21.609 1.00 31.91 ? 471 TRP A NE1 1 ATOM 3777 C CE2 . TRP A 1 471 ? 54.623 99.185 20.324 1.00 30.02 ? 471 TRP A CE2 1 ATOM 3778 C CE3 . TRP A 1 471 ? 53.588 97.271 19.217 1.00 29.82 ? 471 TRP A CE3 1 ATOM 3779 C CZ2 . TRP A 1 471 ? 54.876 99.813 19.093 1.00 30.82 ? 471 TRP A CZ2 1 ATOM 3780 C CZ3 . TRP A 1 471 ? 53.837 97.899 17.976 1.00 29.95 ? 471 TRP A CZ3 1 ATOM 3781 C CH2 . TRP A 1 471 ? 54.488 99.150 17.921 1.00 30.00 ? 471 TRP A CH2 1 ATOM 3782 N N . ALA A 1 472 ? 52.625 93.359 23.429 1.00 34.88 ? 472 ALA A N 1 ATOM 3783 C CA . ALA A 1 472 ? 52.575 92.363 24.512 1.00 36.01 ? 472 ALA A CA 1 ATOM 3784 C C . ALA A 1 472 ? 53.267 91.066 24.107 1.00 35.77 ? 472 ALA A C 1 ATOM 3785 O O . ALA A 1 472 ? 54.003 90.471 24.903 1.00 35.90 ? 472 ALA A O 1 ATOM 3786 C CB . ALA A 1 472 ? 51.134 92.071 24.926 1.00 37.61 ? 472 ALA A CB 1 ATOM 3787 N N . ASN A 1 473 ? 53.038 90.631 22.876 1.00 35.03 ? 473 ASN A N 1 ATOM 3788 C CA . ASN A 1 473 ? 53.791 89.467 22.356 1.00 35.00 ? 473 ASN A CA 1 ATOM 3789 C C . ASN A 1 473 ? 55.276 89.732 22.296 1.00 34.64 ? 473 ASN A C 1 ATOM 3790 O O . ASN A 1 473 ? 56.067 88.851 22.651 1.00 34.90 ? 473 ASN A O 1 ATOM 3791 C CB . ASN A 1 473 ? 53.283 88.986 20.984 1.00 35.09 ? 473 ASN A CB 1 ATOM 3792 C CG . ASN A 1 473 ? 52.003 88.153 21.088 1.00 36.88 ? 473 ASN A CG 1 ATOM 3793 O OD1 . ASN A 1 473 ? 51.520 87.859 22.200 1.00 35.88 ? 473 ASN A OD1 1 ATOM 3794 N ND2 . ASN A 1 473 ? 51.407 87.830 19.928 1.00 34.40 ? 473 ASN A ND2 1 ATOM 3795 N N . PHE A 1 474 ? 55.676 90.939 21.876 1.00 34.41 ? 474 PHE A N 1 ATOM 3796 C CA . PHE A 1 474 ? 57.099 91.296 21.963 1.00 34.06 ? 474 PHE A CA 1 ATOM 3797 C C . PHE A 1 474 ? 57.588 91.137 23.389 1.00 34.80 ? 474 PHE A C 1 ATOM 3798 O O . PHE A 1 474 ? 58.615 90.507 23.644 1.00 35.94 ? 474 PHE A O 1 ATOM 3799 C CB . PHE A 1 474 ? 57.410 92.728 21.470 1.00 33.90 ? 474 PHE A CB 1 ATOM 3800 C CG . PHE A 1 474 ? 58.897 93.052 21.524 1.00 33.44 ? 474 PHE A CG 1 ATOM 3801 C CD1 . PHE A 1 474 ? 59.790 92.452 20.600 1.00 33.24 ? 474 PHE A CD1 1 ATOM 3802 C CD2 . PHE A 1 474 ? 59.402 93.885 22.502 1.00 29.76 ? 474 PHE A CD2 1 ATOM 3803 C CE1 . PHE A 1 474 ? 61.151 92.717 20.654 1.00 33.97 ? 474 PHE A CE1 1 ATOM 3804 C CE2 . PHE A 1 474 ? 60.777 94.193 22.549 1.00 30.79 ? 474 PHE A CE2 1 ATOM 3805 C CZ . PHE A 1 474 ? 61.658 93.572 21.637 1.00 29.57 ? 474 PHE A CZ 1 ATOM 3806 N N . ALA A 1 475 ? 56.867 91.728 24.335 1.00 34.85 ? 475 ALA A N 1 ATOM 3807 C CA . ALA A 1 475 ? 57.302 91.712 25.703 1.00 35.45 ? 475 ALA A CA 1 ATOM 3808 C C . ALA A 1 475 ? 57.396 90.269 26.256 1.00 35.51 ? 475 ALA A C 1 ATOM 3809 O O . ALA A 1 475 ? 58.389 89.878 26.837 1.00 36.35 ? 475 ALA A O 1 ATOM 3810 C CB . ALA A 1 475 ? 56.355 92.538 26.540 1.00 34.83 ? 475 ALA A CB 1 ATOM 3811 N N . LYS A 1 476 ? 56.350 89.498 26.090 1.00 35.79 ? 476 LYS A N 1 ATOM 3812 C CA . LYS A 1 476 ? 56.318 88.157 26.657 1.00 36.93 ? 476 LYS A CA 1 ATOM 3813 C C . LYS A 1 476 ? 57.262 87.202 25.924 1.00 36.88 ? 476 LYS A C 1 ATOM 3814 O O . LYS A 1 476 ? 57.894 86.384 26.570 1.00 37.68 ? 476 LYS A O 1 ATOM 3815 C CB . LYS A 1 476 ? 54.903 87.583 26.616 1.00 36.92 ? 476 LYS A CB 1 ATOM 3816 C CG . LYS A 1 476 ? 53.856 88.347 27.408 1.00 38.61 ? 476 LYS A CG 1 ATOM 3817 C CD . LYS A 1 476 ? 52.489 87.730 27.219 1.00 40.60 ? 476 LYS A CD 1 ATOM 3818 C CE . LYS A 1 476 ? 51.422 88.444 28.078 1.00 45.10 ? 476 LYS A CE 1 ATOM 3819 N NZ . LYS A 1 476 ? 50.057 88.563 27.353 1.00 43.34 ? 476 LYS A NZ 1 ATOM 3820 N N . TYR A 1 477 ? 57.352 87.317 24.600 1.00 36.80 ? 477 TYR A N 1 ATOM 3821 C CA . TYR A 1 477 ? 57.959 86.257 23.766 1.00 38.12 ? 477 TYR A CA 1 ATOM 3822 C C . TYR A 1 477 ? 59.053 86.724 22.824 1.00 38.44 ? 477 TYR A C 1 ATOM 3823 O O . TYR A 1 477 ? 59.654 85.893 22.133 1.00 38.86 ? 477 TYR A O 1 ATOM 3824 C CB . TYR A 1 477 ? 56.881 85.596 22.894 1.00 37.51 ? 477 TYR A CB 1 ATOM 3825 C CG . TYR A 1 477 ? 55.642 85.236 23.660 1.00 37.21 ? 477 TYR A CG 1 ATOM 3826 C CD1 . TYR A 1 477 ? 54.373 85.613 23.208 1.00 36.51 ? 477 TYR A CD1 1 ATOM 3827 C CD2 . TYR A 1 477 ? 55.739 84.525 24.858 1.00 34.67 ? 477 TYR A CD2 1 ATOM 3828 C CE1 . TYR A 1 477 ? 53.218 85.291 23.955 1.00 34.79 ? 477 TYR A CE1 1 ATOM 3829 C CE2 . TYR A 1 477 ? 54.594 84.199 25.596 1.00 37.57 ? 477 TYR A CE2 1 ATOM 3830 C CZ . TYR A 1 477 ? 53.354 84.559 25.145 1.00 38.95 ? 477 TYR A CZ 1 ATOM 3831 O OH . TYR A 1 477 ? 52.267 84.217 25.934 1.00 37.95 ? 477 TYR A OH 1 ATOM 3832 N N . GLY A 1 478 ? 59.279 88.039 22.767 1.00 37.42 ? 478 GLY A N 1 ATOM 3833 C CA . GLY A 1 478 ? 60.353 88.599 21.951 1.00 36.07 ? 478 GLY A CA 1 ATOM 3834 C C . GLY A 1 478 ? 60.019 88.652 20.467 1.00 35.75 ? 478 GLY A C 1 ATOM 3835 O O . GLY A 1 478 ? 60.924 88.760 19.622 1.00 35.79 ? 478 GLY A O 1 ATOM 3836 N N . ASN A 1 479 ? 58.738 88.619 20.143 1.00 35.52 ? 479 ASN A N 1 ATOM 3837 C CA . ASN A 1 479 ? 58.319 88.533 18.746 1.00 36.96 ? 479 ASN A CA 1 ATOM 3838 C C . ASN A 1 479 ? 56.991 89.194 18.553 1.00 36.93 ? 479 ASN A C 1 ATOM 3839 O O . ASN A 1 479 ? 56.006 88.620 18.963 1.00 38.85 ? 479 ASN A O 1 ATOM 3840 C CB . ASN A 1 479 ? 58.214 87.052 18.341 1.00 37.60 ? 479 ASN A CB 1 ATOM 3841 C CG . ASN A 1 479 ? 58.493 86.812 16.845 1.00 38.89 ? 479 ASN A CG 1 ATOM 3842 O OD1 . ASN A 1 479 ? 58.375 87.715 16.001 1.00 40.07 ? 479 ASN A OD1 1 ATOM 3843 N ND2 . ASN A 1 479 ? 58.856 85.575 16.523 1.00 41.49 ? 479 ASN A ND2 1 ATOM 3844 N N . PRO A 1 480 ? 56.959 90.381 17.918 1.00 36.71 ? 480 PRO A N 1 ATOM 3845 C CA . PRO A 1 480 ? 55.770 91.231 17.870 1.00 36.54 ? 480 PRO A CA 1 ATOM 3846 C C . PRO A 1 480 ? 54.774 90.799 16.794 1.00 37.31 ? 480 PRO A C 1 ATOM 3847 O O . PRO A 1 480 ? 54.357 91.593 15.924 1.00 36.68 ? 480 PRO A O 1 ATOM 3848 C CB . PRO A 1 480 ? 56.362 92.620 17.554 1.00 36.39 ? 480 PRO A CB 1 ATOM 3849 C CG . PRO A 1 480 ? 57.529 92.281 16.586 1.00 34.47 ? 480 PRO A CG 1 ATOM 3850 C CD . PRO A 1 480 ? 58.103 91.019 17.227 1.00 36.40 ? 480 PRO A CD 1 ATOM 3851 N N . GLN A 1 481 ? 54.383 89.534 16.860 1.00 37.61 ? 481 GLN A N 1 ATOM 3852 C CA . GLN A 1 481 ? 53.420 89.011 15.907 1.00 37.23 ? 481 GLN A CA 1 ATOM 3853 C C . GLN A 1 481 ? 52.047 89.142 16.506 1.00 37.85 ? 481 GLN A C 1 ATOM 3854 O O . GLN A 1 481 ? 51.891 89.192 17.744 1.00 38.15 ? 481 GLN A O 1 ATOM 3855 C CB . GLN A 1 481 ? 53.724 87.532 15.557 1.00 36.23 ? 481 GLN A CB 1 ATOM 3856 C CG . GLN A 1 481 ? 55.171 87.251 15.055 1.00 35.83 ? 481 GLN A CG 1 ATOM 3857 C CD . GLN A 1 481 ? 55.622 88.114 13.866 1.00 34.82 ? 481 GLN A CD 1 ATOM 3858 O OE1 . GLN A 1 481 ? 54.808 88.516 13.022 1.00 34.29 ? 481 GLN A OE1 1 ATOM 3859 N NE2 . GLN A 1 481 ? 56.934 88.400 13.810 1.00 32.01 ? 481 GLN A NE2 1 ATOM 3860 N N . GLU A 1 482 ? 51.058 89.235 15.631 1.00 38.42 ? 482 GLU A N 1 ATOM 3861 C CA . GLU A 1 482 ? 49.680 89.019 16.001 1.00 41.55 ? 482 GLU A CA 1 ATOM 3862 C C . GLU A 1 482 ? 49.330 87.715 15.277 1.00 42.29 ? 482 GLU A C 1 ATOM 3863 O O . GLU A 1 482 ? 49.164 87.728 14.068 1.00 43.25 ? 482 GLU A O 1 ATOM 3864 C CB . GLU A 1 482 ? 48.791 90.179 15.513 1.00 41.54 ? 482 GLU A CB 1 ATOM 3865 C CG . GLU A 1 482 ? 47.348 90.155 16.062 1.00 44.26 ? 482 GLU A CG 1 ATOM 3866 C CD . GLU A 1 482 ? 46.542 88.959 15.538 1.00 46.95 ? 482 GLU A CD 1 ATOM 3867 O OE1 . GLU A 1 482 ? 46.067 88.148 16.340 1.00 45.52 ? 482 GLU A OE1 1 ATOM 3868 O OE2 . GLU A 1 482 ? 46.433 88.787 14.301 1.00 52.19 ? 482 GLU A OE2 1 ATOM 3869 N N . THR A 1 483 ? 49.252 86.592 15.986 1.00 42.89 ? 483 THR A N 1 ATOM 3870 C CA . THR A 1 483 ? 49.170 85.291 15.282 1.00 44.26 ? 483 THR A CA 1 ATOM 3871 C C . THR A 1 483 ? 47.753 84.728 14.892 1.00 45.75 ? 483 THR A C 1 ATOM 3872 O O . THR A 1 483 ? 47.655 83.695 14.212 1.00 45.15 ? 483 THR A O 1 ATOM 3873 C CB . THR A 1 483 ? 49.915 84.224 16.093 1.00 43.27 ? 483 THR A CB 1 ATOM 3874 O OG1 . THR A 1 483 ? 49.317 84.154 17.392 1.00 43.92 ? 483 THR A OG1 1 ATOM 3875 C CG2 . THR A 1 483 ? 51.323 84.660 16.370 1.00 42.53 ? 483 THR A CG2 1 ATOM 3876 N N . GLN A 1 484 ? 46.683 85.379 15.329 1.00 47.56 ? 484 GLN A N 1 ATOM 3877 C CA . GLN A 1 484 ? 45.357 84.775 15.253 1.00 50.06 ? 484 GLN A CA 1 ATOM 3878 C C . GLN A 1 484 ? 44.485 85.276 14.115 1.00 51.14 ? 484 GLN A C 1 ATOM 3879 O O . GLN A 1 484 ? 43.569 84.585 13.696 1.00 51.23 ? 484 GLN A O 1 ATOM 3880 C CB . GLN A 1 484 ? 44.613 84.979 16.572 1.00 49.49 ? 484 GLN A CB 1 ATOM 3881 C CG . GLN A 1 484 ? 45.281 84.284 17.715 1.00 52.34 ? 484 GLN A CG 1 ATOM 3882 C CD . GLN A 1 484 ? 44.610 84.524 19.074 1.00 56.51 ? 484 GLN A CD 1 ATOM 3883 O OE1 . GLN A 1 484 ? 44.054 85.618 19.355 1.00 58.62 ? 484 GLN A OE1 1 ATOM 3884 N NE2 . GLN A 1 484 ? 44.666 83.496 19.932 1.00 56.18 ? 484 GLN A NE2 1 ATOM 3885 N N . ASN A 1 485 ? 44.737 86.487 13.634 1.00 53.22 ? 485 ASN A N 1 ATOM 3886 C CA . ASN A 1 485 ? 43.784 87.117 12.725 1.00 55.06 ? 485 ASN A CA 1 ATOM 3887 C C . ASN A 1 485 ? 44.308 87.355 11.325 1.00 55.81 ? 485 ASN A C 1 ATOM 3888 O O . ASN A 1 485 ? 44.004 88.377 10.711 1.00 57.05 ? 485 ASN A O 1 ATOM 3889 C CB . ASN A 1 485 ? 43.183 88.389 13.346 1.00 55.58 ? 485 ASN A CB 1 ATOM 3890 C CG . ASN A 1 485 ? 42.357 88.100 14.612 1.00 57.85 ? 485 ASN A CG 1 ATOM 3891 O OD1 . ASN A 1 485 ? 41.987 86.956 14.887 1.00 58.77 ? 485 ASN A OD1 1 ATOM 3892 N ND2 . ASN A 1 485 ? 42.112 89.150 15.404 1.00 64.18 ? 485 ASN A ND2 1 ATOM 3893 N N . GLN A 1 486 ? 45.069 86.386 10.820 1.00 56.74 ? 486 GLN A N 1 ATOM 3894 C CA . GLN A 1 486 ? 45.632 86.404 9.468 1.00 57.46 ? 486 GLN A CA 1 ATOM 3895 C C . GLN A 1 486 ? 46.365 87.718 9.211 1.00 56.90 ? 486 GLN A C 1 ATOM 3896 O O . GLN A 1 486 ? 46.189 88.363 8.164 1.00 57.81 ? 486 GLN A O 1 ATOM 3897 C CB . GLN A 1 486 ? 44.549 86.186 8.402 1.00 58.68 ? 486 GLN A CB 1 ATOM 3898 C CG . GLN A 1 486 ? 43.506 85.099 8.732 1.00 62.55 ? 486 GLN A CG 1 ATOM 3899 C CD . GLN A 1 486 ? 42.109 85.497 8.238 1.00 67.14 ? 486 GLN A CD 1 ATOM 3900 O OE1 . GLN A 1 486 ? 41.330 86.110 8.992 1.00 70.41 ? 486 GLN A OE1 1 ATOM 3901 N NE2 . GLN A 1 486 ? 41.803 85.183 6.969 1.00 66.51 ? 486 GLN A NE2 1 ATOM 3902 N N . SER A 1 487 ? 47.178 88.111 10.183 1.00 54.70 ? 487 SER A N 1 ATOM 3903 C CA . SER A 1 487 ? 47.907 89.356 10.128 1.00 52.97 ? 487 SER A CA 1 ATOM 3904 C C . SER A 1 487 ? 49.171 89.199 9.318 1.00 51.40 ? 487 SER A C 1 ATOM 3905 O O . SER A 1 487 ? 49.730 88.100 9.230 1.00 50.97 ? 487 SER A O 1 ATOM 3906 C CB . SER A 1 487 ? 48.283 89.803 11.542 1.00 52.33 ? 487 SER A CB 1 ATOM 3907 O OG . SER A 1 487 ? 47.120 90.157 12.252 1.00 53.84 ? 487 SER A OG 1 ATOM 3908 N N . THR A 1 488 ? 49.619 90.314 8.750 1.00 49.70 ? 488 THR A N 1 ATOM 3909 C CA . THR A 1 488 ? 50.932 90.393 8.127 1.00 48.40 ? 488 THR A CA 1 ATOM 3910 C C . THR A 1 488 ? 51.944 90.025 9.196 1.00 47.62 ? 488 THR A C 1 ATOM 3911 O O . THR A 1 488 ? 51.859 90.476 10.348 1.00 46.81 ? 488 THR A O 1 ATOM 3912 C CB . THR A 1 488 ? 51.193 91.818 7.627 1.00 48.65 ? 488 THR A CB 1 ATOM 3913 O OG1 . THR A 1 488 ? 50.142 92.198 6.725 1.00 49.37 ? 488 THR A OG1 1 ATOM 3914 C CG2 . THR A 1 488 ? 52.439 91.873 6.762 1.00 48.67 ? 488 THR A CG2 1 ATOM 3915 N N . SER A 1 489 ? 52.865 89.164 8.797 1.00 45.96 ? 489 SER A N 1 ATOM 3916 C CA . SER A 1 489 ? 53.945 88.718 9.621 1.00 45.46 ? 489 SER A CA 1 ATOM 3917 C C . SER A 1 489 ? 55.040 89.822 9.638 1.00 43.55 ? 489 SER A C 1 ATOM 3918 O O . SER A 1 489 ? 55.333 90.426 8.618 1.00 43.14 ? 489 SER A O 1 ATOM 3919 C CB . SER A 1 489 ? 54.441 87.381 9.068 1.00 46.30 ? 489 SER A CB 1 ATOM 3920 O OG . SER A 1 489 ? 55.731 87.102 9.573 1.00 52.20 ? 489 SER A OG 1 ATOM 3921 N N . TRP A 1 490 ? 55.564 90.138 10.823 1.00 40.56 ? 490 TRP A N 1 ATOM 3922 C CA . TRP A 1 490 ? 56.467 91.257 10.966 1.00 38.00 ? 490 TRP A CA 1 ATOM 3923 C C . TRP A 1 490 ? 57.872 90.672 10.822 1.00 37.12 ? 490 TRP A C 1 ATOM 3924 O O . TRP A 1 490 ? 58.264 89.904 11.661 1.00 35.99 ? 490 TRP A O 1 ATOM 3925 C CB . TRP A 1 490 ? 56.288 91.892 12.353 1.00 36.83 ? 490 TRP A CB 1 ATOM 3926 C CG . TRP A 1 490 ? 57.006 93.184 12.555 1.00 35.55 ? 490 TRP A CG 1 ATOM 3927 C CD1 . TRP A 1 490 ? 58.097 93.651 11.868 1.00 35.31 ? 490 TRP A CD1 1 ATOM 3928 C CD2 . TRP A 1 490 ? 56.676 94.202 13.507 1.00 34.53 ? 490 TRP A CD2 1 ATOM 3929 N NE1 . TRP A 1 490 ? 58.449 94.902 12.316 1.00 33.14 ? 490 TRP A NE1 1 ATOM 3930 C CE2 . TRP A 1 490 ? 57.613 95.256 13.342 1.00 33.56 ? 490 TRP A CE2 1 ATOM 3931 C CE3 . TRP A 1 490 ? 55.666 94.343 14.476 1.00 30.36 ? 490 TRP A CE3 1 ATOM 3932 C CZ2 . TRP A 1 490 ? 57.582 96.421 14.120 1.00 32.67 ? 490 TRP A CZ2 1 ATOM 3933 C CZ3 . TRP A 1 490 ? 55.635 95.496 15.258 1.00 34.70 ? 490 TRP A CZ3 1 ATOM 3934 C CH2 . TRP A 1 490 ? 56.596 96.507 15.089 1.00 35.12 ? 490 TRP A CH2 1 ATOM 3935 N N . PRO A 1 491 ? 58.611 90.973 9.749 1.00 37.05 ? 491 PRO A N 1 ATOM 3936 C CA . PRO A 1 491 ? 59.920 90.376 9.577 1.00 37.25 ? 491 PRO A CA 1 ATOM 3937 C C . PRO A 1 491 ? 60.958 91.044 10.453 1.00 37.61 ? 491 PRO A C 1 ATOM 3938 O O . PRO A 1 491 ? 60.858 92.230 10.758 1.00 37.99 ? 491 PRO A O 1 ATOM 3939 C CB . PRO A 1 491 ? 60.248 90.646 8.102 1.00 37.60 ? 491 PRO A CB 1 ATOM 3940 C CG . PRO A 1 491 ? 59.566 91.953 7.820 1.00 38.23 ? 491 PRO A CG 1 ATOM 3941 C CD . PRO A 1 491 ? 58.244 91.839 8.608 1.00 37.57 ? 491 PRO A CD 1 ATOM 3942 N N . VAL A 1 492 ? 61.945 90.274 10.861 1.00 37.09 ? 492 VAL A N 1 ATOM 3943 C CA . VAL A 1 492 ? 63.131 90.829 11.439 1.00 38.02 ? 492 VAL A CA 1 ATOM 3944 C C . VAL A 1 492 ? 63.769 91.894 10.502 1.00 38.15 ? 492 VAL A C 1 ATOM 3945 O O . VAL A 1 492 ? 63.802 91.763 9.236 1.00 37.30 ? 492 VAL A O 1 ATOM 3946 C CB . VAL A 1 492 ? 64.078 89.664 11.811 1.00 38.41 ? 492 VAL A CB 1 ATOM 3947 C CG1 . VAL A 1 492 ? 65.427 90.120 12.013 1.00 41.79 ? 492 VAL A CG1 1 ATOM 3948 C CG2 . VAL A 1 492 ? 63.570 88.943 13.108 1.00 40.13 ? 492 VAL A CG2 1 ATOM 3949 N N . PHE A 1 493 ? 64.246 92.957 11.129 1.00 38.25 ? 493 PHE A N 1 ATOM 3950 C CA . PHE A 1 493 ? 65.048 93.993 10.463 1.00 39.18 ? 493 PHE A CA 1 ATOM 3951 C C . PHE A 1 493 ? 66.525 93.595 10.513 1.00 41.45 ? 493 PHE A C 1 ATOM 3952 O O . PHE A 1 493 ? 67.074 93.387 11.594 1.00 40.82 ? 493 PHE A O 1 ATOM 3953 C CB . PHE A 1 493 ? 64.850 95.339 11.180 1.00 37.35 ? 493 PHE A CB 1 ATOM 3954 C CG . PHE A 1 493 ? 65.585 96.503 10.572 1.00 36.55 ? 493 PHE A CG 1 ATOM 3955 C CD1 . PHE A 1 493 ? 66.947 96.684 10.798 1.00 35.91 ? 493 PHE A CD1 1 ATOM 3956 C CD2 . PHE A 1 493 ? 64.889 97.459 9.816 1.00 35.64 ? 493 PHE A CD2 1 ATOM 3957 C CE1 . PHE A 1 493 ? 67.628 97.778 10.273 1.00 35.72 ? 493 PHE A CE1 1 ATOM 3958 C CE2 . PHE A 1 493 ? 65.535 98.583 9.292 1.00 36.12 ? 493 PHE A CE2 1 ATOM 3959 C CZ . PHE A 1 493 ? 66.914 98.753 9.523 1.00 36.40 ? 493 PHE A CZ 1 ATOM 3960 N N . LYS A 1 494 ? 67.139 93.491 9.335 1.00 43.19 ? 494 LYS A N 1 ATOM 3961 C CA . LYS A 1 494 ? 68.543 93.150 9.189 1.00 46.21 ? 494 LYS A CA 1 ATOM 3962 C C . LYS A 1 494 ? 69.203 94.260 8.380 1.00 46.81 ? 494 LYS A C 1 ATOM 3963 O O . LYS A 1 494 ? 68.542 94.871 7.542 1.00 47.14 ? 494 LYS A O 1 ATOM 3964 C CB . LYS A 1 494 ? 68.667 91.813 8.469 1.00 47.12 ? 494 LYS A CB 1 ATOM 3965 C CG . LYS A 1 494 ? 68.414 90.607 9.366 1.00 50.99 ? 494 LYS A CG 1 ATOM 3966 C CD . LYS A 1 494 ? 68.214 89.355 8.520 1.00 58.49 ? 494 LYS A CD 1 ATOM 3967 C CE . LYS A 1 494 ? 68.335 88.071 9.351 1.00 61.96 ? 494 LYS A CE 1 ATOM 3968 N NZ . LYS A 1 494 ? 66.983 87.488 9.649 1.00 65.29 ? 494 LYS A NZ 1 ATOM 3969 N N . SER A 1 495 ? 70.488 94.540 8.616 1.00 47.90 ? 495 SER A N 1 ATOM 3970 C CA . SER A 1 495 ? 71.099 95.743 8.024 1.00 49.33 ? 495 SER A CA 1 ATOM 3971 C C . SER A 1 495 ? 71.224 95.699 6.495 1.00 48.98 ? 495 SER A C 1 ATOM 3972 O O . SER A 1 495 ? 71.400 96.740 5.874 1.00 49.29 ? 495 SER A O 1 ATOM 3973 C CB . SER A 1 495 ? 72.453 96.071 8.652 1.00 50.79 ? 495 SER A CB 1 ATOM 3974 O OG . SER A 1 495 ? 73.479 95.358 7.977 1.00 54.11 ? 495 SER A OG 1 ATOM 3975 N N . THR A 1 496 ? 71.097 94.510 5.906 1.00 48.38 ? 496 THR A N 1 ATOM 3976 C CA . THR A 1 496 ? 71.061 94.346 4.451 1.00 49.17 ? 496 THR A CA 1 ATOM 3977 C C . THR A 1 496 ? 69.691 94.692 3.847 1.00 47.41 ? 496 THR A C 1 ATOM 3978 O O . THR A 1 496 ? 69.539 95.686 3.128 1.00 46.75 ? 496 THR A O 1 ATOM 3979 C CB . THR A 1 496 ? 71.424 92.879 4.083 1.00 50.58 ? 496 THR A CB 1 ATOM 3980 O OG1 . THR A 1 496 ? 71.007 92.006 5.169 1.00 55.77 ? 496 THR A OG1 1 ATOM 3981 C CG2 . THR A 1 496 ? 72.953 92.693 4.035 1.00 51.97 ? 496 THR A CG2 1 ATOM 3982 N N . GLU A 1 497 ? 68.692 93.882 4.158 1.00 45.28 ? 497 GLU A N 1 ATOM 3983 C CA . GLU A 1 497 ? 67.371 94.073 3.579 1.00 44.27 ? 497 GLU A CA 1 ATOM 3984 C C . GLU A 1 497 ? 66.544 95.219 4.197 1.00 41.26 ? 497 GLU A C 1 ATOM 3985 O O . GLU A 1 497 ? 65.814 95.928 3.478 1.00 38.57 ? 497 GLU A O 1 ATOM 3986 C CB . GLU A 1 497 ? 66.625 92.755 3.567 1.00 45.13 ? 497 GLU A CB 1 ATOM 3987 C CG . GLU A 1 497 ? 67.244 91.770 2.558 1.00 50.17 ? 497 GLU A CG 1 ATOM 3988 C CD . GLU A 1 497 ? 66.447 90.481 2.465 1.00 57.74 ? 497 GLU A CD 1 ATOM 3989 O OE1 . GLU A 1 497 ? 65.761 90.257 1.421 1.00 61.20 ? 497 GLU A OE1 1 ATOM 3990 O OE2 . GLU A 1 497 ? 66.462 89.708 3.452 1.00 59.47 ? 497 GLU A OE2 1 ATOM 3991 N N . GLN A 1 498 ? 66.676 95.388 5.512 1.00 38.78 ? 498 GLN A N 1 ATOM 3992 C CA . GLN A 1 498 ? 66.097 96.559 6.191 1.00 37.54 ? 498 GLN A CA 1 ATOM 3993 C C . GLN A 1 498 ? 64.585 96.593 5.998 1.00 35.84 ? 498 GLN A C 1 ATOM 3994 O O . GLN A 1 498 ? 64.013 97.630 5.648 1.00 36.15 ? 498 GLN A O 1 ATOM 3995 C CB . GLN A 1 498 ? 66.747 97.857 5.653 1.00 37.86 ? 498 GLN A CB 1 ATOM 3996 C CG . GLN A 1 498 ? 68.210 97.988 6.011 1.00 40.59 ? 498 GLN A CG 1 ATOM 3997 C CD . GLN A 1 498 ? 68.946 99.015 5.169 1.00 44.40 ? 498 GLN A CD 1 ATOM 3998 O OE1 . GLN A 1 498 ? 68.505 100.142 5.006 1.00 43.06 ? 498 GLN A OE1 1 ATOM 3999 N NE2 . GLN A 1 498 ? 70.073 98.605 4.618 1.00 49.70 ? 498 GLN A NE2 1 ATOM 4000 N N . LYS A 1 499 ? 63.951 95.446 6.197 1.00 34.14 ? 499 LYS A N 1 ATOM 4001 C CA . LYS A 1 499 ? 62.489 95.340 6.169 1.00 34.46 ? 499 LYS A CA 1 ATOM 4002 C C . LYS A 1 499 ? 61.870 95.991 7.384 1.00 34.07 ? 499 LYS A C 1 ATOM 4003 O O . LYS A 1 499 ? 62.393 95.849 8.513 1.00 34.47 ? 499 LYS A O 1 ATOM 4004 C CB . LYS A 1 499 ? 62.023 93.871 6.096 1.00 33.56 ? 499 LYS A CB 1 ATOM 4005 C CG . LYS A 1 499 ? 62.564 93.125 4.868 1.00 34.58 ? 499 LYS A CG 1 ATOM 4006 C CD . LYS A 1 499 ? 61.905 91.760 4.670 1.00 34.40 ? 499 LYS A CD 1 ATOM 4007 C CE . LYS A 1 499 ? 62.587 91.022 3.484 1.00 35.38 ? 499 LYS A CE 1 ATOM 4008 N NZ . LYS A 1 499 ? 62.176 89.598 3.534 1.00 35.91 ? 499 LYS A NZ 1 ATOM 4009 N N . TYR A 1 500 ? 60.770 96.701 7.149 1.00 33.48 ? 500 TYR A N 1 ATOM 4010 C CA . TYR A 1 500 ? 59.995 97.270 8.242 1.00 34.22 ? 500 TYR A CA 1 ATOM 4011 C C . TYR A 1 500 ? 58.501 97.038 7.984 1.00 34.92 ? 500 TYR A C 1 ATOM 4012 O O . TYR A 1 500 ? 58.085 96.836 6.843 1.00 35.12 ? 500 TYR A O 1 ATOM 4013 C CB . TYR A 1 500 ? 60.325 98.754 8.423 1.00 32.22 ? 500 TYR A CB 1 ATOM 4014 C CG . TYR A 1 500 ? 59.953 99.666 7.254 1.00 31.75 ? 500 TYR A CG 1 ATOM 4015 C CD1 . TYR A 1 500 ? 60.800 99.792 6.136 1.00 29.22 ? 500 TYR A CD1 1 ATOM 4016 C CD2 . TYR A 1 500 ? 58.784 100.444 7.295 1.00 29.33 ? 500 TYR A CD2 1 ATOM 4017 C CE1 . TYR A 1 500 ? 60.496 100.640 5.069 1.00 29.82 ? 500 TYR A CE1 1 ATOM 4018 C CE2 . TYR A 1 500 ? 58.461 101.296 6.226 1.00 32.50 ? 500 TYR A CE2 1 ATOM 4019 C CZ . TYR A 1 500 ? 59.327 101.373 5.114 1.00 30.88 ? 500 TYR A CZ 1 ATOM 4020 O OH . TYR A 1 500 ? 59.018 102.195 4.073 1.00 32.41 ? 500 TYR A OH 1 ATOM 4021 N N . LEU A 1 501 ? 57.709 97.101 9.043 1.00 35.01 ? 501 LEU A N 1 ATOM 4022 C CA . LEU A 1 501 ? 56.250 96.964 8.930 1.00 35.66 ? 501 LEU A CA 1 ATOM 4023 C C . LEU A 1 501 ? 55.568 98.347 9.034 1.00 35.53 ? 501 LEU A C 1 ATOM 4024 O O . LEU A 1 501 ? 55.920 99.141 9.905 1.00 35.11 ? 501 LEU A O 1 ATOM 4025 C CB . LEU A 1 501 ? 55.739 96.025 10.038 1.00 34.72 ? 501 LEU A CB 1 ATOM 4026 C CG . LEU A 1 501 ? 54.233 95.700 10.179 1.00 37.57 ? 501 LEU A CG 1 ATOM 4027 C CD1 . LEU A 1 501 ? 53.792 94.769 9.094 1.00 38.76 ? 501 LEU A CD1 1 ATOM 4028 C CD2 . LEU A 1 501 ? 53.921 95.062 11.511 1.00 37.65 ? 501 LEU A CD2 1 ATOM 4029 N N . THR A 1 502 ? 54.605 98.635 8.159 1.00 35.76 ? 502 THR A N 1 ATOM 4030 C CA . THR A 1 502 ? 53.789 99.826 8.331 1.00 37.62 ? 502 THR A CA 1 ATOM 4031 C C . THR A 1 502 ? 52.540 99.533 9.184 1.00 37.86 ? 502 THR A C 1 ATOM 4032 O O . THR A 1 502 ? 51.924 98.445 9.102 1.00 37.95 ? 502 THR A O 1 ATOM 4033 C CB . THR A 1 502 ? 53.378 100.507 7.004 1.00 38.85 ? 502 THR A CB 1 ATOM 4034 O OG1 . THR A 1 502 ? 52.554 99.606 6.240 1.00 38.02 ? 502 THR A OG1 1 ATOM 4035 C CG2 . THR A 1 502 ? 54.629 100.825 6.121 1.00 37.02 ? 502 THR A CG2 1 ATOM 4036 N N . LEU A 1 503 ? 52.165 100.533 9.968 1.00 37.05 ? 503 LEU A N 1 ATOM 4037 C CA . LEU A 1 503 ? 51.044 100.434 10.888 1.00 37.70 ? 503 LEU A CA 1 ATOM 4038 C C . LEU A 1 503 ? 50.039 101.495 10.482 1.00 39.04 ? 503 LEU A C 1 ATOM 4039 O O . LEU A 1 503 ? 50.325 102.688 10.524 1.00 38.19 ? 503 LEU A O 1 ATOM 4040 C CB . LEU A 1 503 ? 51.504 100.663 12.333 1.00 35.92 ? 503 LEU A CB 1 ATOM 4041 C CG . LEU A 1 503 ? 52.523 99.690 12.948 1.00 36.42 ? 503 LEU A CG 1 ATOM 4042 C CD1 . LEU A 1 503 ? 52.912 100.138 14.370 1.00 32.91 ? 503 LEU A CD1 1 ATOM 4043 C CD2 . LEU A 1 503 ? 51.981 98.228 12.939 1.00 34.89 ? 503 LEU A CD2 1 ATOM 4044 N N . ASN A 1 504 ? 48.845 101.047 10.101 1.00 41.71 ? 504 ASN A N 1 ATOM 4045 C CA . ASN A 1 504 ? 47.824 101.946 9.548 1.00 44.04 ? 504 ASN A CA 1 ATOM 4046 C C . ASN A 1 504 ? 46.502 101.213 9.588 1.00 45.13 ? 504 ASN A C 1 ATOM 4047 O O . ASN A 1 504 ? 46.498 99.992 9.749 1.00 44.31 ? 504 ASN A O 1 ATOM 4048 C CB . ASN A 1 504 ? 48.198 102.348 8.106 1.00 43.81 ? 504 ASN A CB 1 ATOM 4049 C CG . ASN A 1 504 ? 48.215 101.158 7.172 1.00 46.10 ? 504 ASN A CG 1 ATOM 4050 O OD1 . ASN A 1 504 ? 47.178 100.556 6.925 1.00 46.84 ? 504 ASN A OD1 1 ATOM 4051 N ND2 . ASN A 1 504 ? 49.397 100.803 6.653 1.00 48.19 ? 504 ASN A ND2 1 ATOM 4052 N N . THR A 1 505 ? 45.381 101.923 9.429 1.00 47.67 ? 505 THR A N 1 ATOM 4053 C CA . THR A 1 505 ? 44.087 101.217 9.485 1.00 50.39 ? 505 THR A CA 1 ATOM 4054 C C . THR A 1 505 ? 43.791 100.432 8.199 1.00 53.67 ? 505 THR A C 1 ATOM 4055 O O . THR A 1 505 ? 43.205 99.345 8.261 1.00 54.90 ? 505 THR A O 1 ATOM 4056 C CB . THR A 1 505 ? 42.898 102.135 9.822 1.00 49.77 ? 505 THR A CB 1 ATOM 4057 O OG1 . THR A 1 505 ? 42.770 103.152 8.822 1.00 48.99 ? 505 THR A OG1 1 ATOM 4058 C CG2 . THR A 1 505 ? 43.118 102.889 11.144 1.00 46.97 ? 505 THR A CG2 1 ATOM 4059 N N . GLU A 1 506 ? 44.180 100.962 7.043 1.00 56.14 ? 506 GLU A N 1 ATOM 4060 C CA . GLU A 1 506 ? 43.878 100.249 5.783 1.00 59.00 ? 506 GLU A CA 1 ATOM 4061 C C . GLU A 1 506 ? 44.610 98.900 5.654 1.00 59.59 ? 506 GLU A C 1 ATOM 4062 O O . GLU A 1 506 ? 44.121 97.879 6.152 1.00 61.37 ? 506 GLU A O 1 ATOM 4063 C CB . GLU A 1 506 ? 44.086 101.144 4.557 1.00 59.50 ? 506 GLU A CB 1 ATOM 4064 C CG . GLU A 1 506 ? 45.449 101.807 4.470 1.00 63.85 ? 506 GLU A CG 1 ATOM 4065 C CD . GLU A 1 506 ? 45.470 102.907 3.432 1.00 70.26 ? 506 GLU A CD 1 ATOM 4066 O OE1 . GLU A 1 506 ? 46.360 102.854 2.526 1.00 73.78 ? 506 GLU A OE1 1 ATOM 4067 O OE2 . GLU A 1 506 ? 44.592 103.810 3.519 1.00 70.69 ? 506 GLU A OE2 1 ATOM 4068 N N . SER A 1 507 ? 45.774 98.889 5.008 1.00 59.79 ? 507 SER A N 1 ATOM 4069 C CA . SER A 1 507 ? 46.522 97.648 4.779 1.00 59.11 ? 507 SER A CA 1 ATOM 4070 C C . SER A 1 507 ? 47.933 97.767 5.299 1.00 57.78 ? 507 SER A C 1 ATOM 4071 O O . SER A 1 507 ? 48.632 98.747 5.011 1.00 58.02 ? 507 SER A O 1 ATOM 4072 C CB . SER A 1 507 ? 46.595 97.342 3.276 1.00 59.97 ? 507 SER A CB 1 ATOM 4073 O OG . SER A 1 507 ? 47.387 98.325 2.629 1.00 61.73 ? 507 SER A OG 1 ATOM 4074 N N . THR A 1 508 ? 48.359 96.773 6.058 1.00 56.08 ? 508 THR A N 1 ATOM 4075 C CA . THR A 1 508 ? 49.664 96.837 6.662 1.00 54.57 ? 508 THR A CA 1 ATOM 4076 C C . THR A 1 508 ? 50.655 96.202 5.709 1.00 52.62 ? 508 THR A C 1 ATOM 4077 O O . THR A 1 508 ? 50.376 95.166 5.108 1.00 52.56 ? 508 THR A O 1 ATOM 4078 C CB . THR A 1 508 ? 49.648 96.214 8.065 1.00 55.20 ? 508 THR A CB 1 ATOM 4079 O OG1 . THR A 1 508 ? 50.300 94.941 8.085 1.00 55.67 ? 508 THR A OG1 1 ATOM 4080 C CG2 . THR A 1 508 ? 48.227 95.932 8.441 1.00 55.61 ? 508 THR A CG2 1 ATOM 4081 N N . ARG A 1 509 ? 51.791 96.862 5.531 1.00 49.83 ? 509 ARG A N 1 ATOM 4082 C CA . ARG A 1 509 ? 52.744 96.402 4.552 1.00 47.31 ? 509 ARG A CA 1 ATOM 4083 C C . ARG A 1 509 ? 54.128 96.138 5.077 1.00 44.98 ? 509 ARG A C 1 ATOM 4084 O O . ARG A 1 509 ? 54.601 96.804 5.992 1.00 43.42 ? 509 ARG A O 1 ATOM 4085 C CB . ARG A 1 509 ? 52.803 97.393 3.387 1.00 48.22 ? 509 ARG A CB 1 ATOM 4086 C CG . ARG A 1 509 ? 51.584 97.252 2.522 1.00 51.10 ? 509 ARG A CG 1 ATOM 4087 C CD . ARG A 1 509 ? 51.149 98.473 1.732 1.00 58.22 ? 509 ARG A CD 1 ATOM 4088 N NE . ARG A 1 509 ? 49.747 98.279 1.314 1.00 63.54 ? 509 ARG A NE 1 ATOM 4089 C CZ . ARG A 1 509 ? 49.316 97.355 0.437 1.00 65.57 ? 509 ARG A CZ 1 ATOM 4090 N NH1 . ARG A 1 509 ? 50.168 96.535 -0.176 1.00 63.82 ? 509 ARG A NH1 1 ATOM 4091 N NH2 . ARG A 1 509 ? 48.013 97.253 0.180 1.00 66.51 ? 509 ARG A NH2 1 ATOM 4092 N N . ILE A 1 510 ? 54.773 95.152 4.451 1.00 42.07 ? 510 ILE A N 1 ATOM 4093 C CA . ILE A 1 510 ? 56.186 94.992 4.535 1.00 39.33 ? 510 ILE A CA 1 ATOM 4094 C C . ILE A 1 510 ? 56.831 95.844 3.436 1.00 38.43 ? 510 ILE A C 1 ATOM 4095 O O . ILE A 1 510 ? 56.540 95.676 2.234 1.00 36.85 ? 510 ILE A O 1 ATOM 4096 C CB . ILE A 1 510 ? 56.591 93.524 4.433 1.00 39.58 ? 510 ILE A CB 1 ATOM 4097 C CG1 . ILE A 1 510 ? 55.899 92.676 5.517 1.00 40.75 ? 510 ILE A CG1 1 ATOM 4098 C CG2 . ILE A 1 510 ? 58.080 93.375 4.634 1.00 40.10 ? 510 ILE A CG2 1 ATOM 4099 C CD1 . ILE A 1 510 ? 55.910 93.364 6.960 1.00 41.96 ? 510 ILE A CD1 1 ATOM 4100 N N A MET A 1 511 ? 57.695 96.764 3.861 0.50 36.92 ? 511 MET A N 1 ATOM 4101 N N B MET A 1 511 ? 57.716 96.739 3.883 0.50 36.75 ? 511 MET A N 1 ATOM 4102 C CA A MET A 1 511 ? 58.454 97.612 2.947 0.50 36.65 ? 511 MET A CA 1 ATOM 4103 C CA B MET A 1 511 ? 58.441 97.685 3.034 0.50 36.37 ? 511 MET A CA 1 ATOM 4104 C C A MET A 1 511 ? 59.933 97.561 3.294 0.50 35.52 ? 511 MET A C 1 ATOM 4105 C C B MET A 1 511 ? 59.934 97.616 3.342 0.50 35.34 ? 511 MET A C 1 ATOM 4106 O O A MET A 1 511 ? 60.324 96.910 4.271 0.50 34.52 ? 511 MET A O 1 ATOM 4107 O O B MET A 1 511 ? 60.332 97.023 4.354 0.50 34.23 ? 511 MET A O 1 ATOM 4108 C CB A MET A 1 511 ? 57.915 99.041 2.970 0.50 36.89 ? 511 MET A CB 1 ATOM 4109 C CB B MET A 1 511 ? 57.925 99.097 3.297 0.50 36.38 ? 511 MET A CB 1 ATOM 4110 C CG A MET A 1 511 ? 56.436 99.126 2.557 0.50 38.44 ? 511 MET A CG 1 ATOM 4111 C CG B MET A 1 511 ? 56.418 99.258 3.073 0.50 37.64 ? 511 MET A CG 1 ATOM 4112 S SD A MET A 1 511 ? 55.757 100.785 2.470 0.50 41.28 ? 511 MET A SD 1 ATOM 4113 S SD B MET A 1 511 ? 56.006 99.061 1.331 0.50 38.87 ? 511 MET A SD 1 ATOM 4114 C CE A MET A 1 511 ? 56.640 101.409 1.064 0.50 38.67 ? 511 MET A CE 1 ATOM 4115 C CE B MET A 1 511 ? 56.547 100.646 0.712 0.50 38.64 ? 511 MET A CE 1 ATOM 4116 N N . THR A 1 512 ? 60.758 98.204 2.478 1.00 35.20 ? 512 THR A N 1 ATOM 4117 C CA . THR A 1 512 ? 62.225 98.177 2.674 1.00 34.61 ? 512 THR A CA 1 ATOM 4118 C C . THR A 1 512 ? 62.883 99.554 2.620 1.00 34.00 ? 512 THR A C 1 ATOM 4119 O O . THR A 1 512 ? 62.463 100.434 1.841 1.00 31.96 ? 512 THR A O 1 ATOM 4120 C CB . THR A 1 512 ? 62.895 97.235 1.637 1.00 35.75 ? 512 THR A CB 1 ATOM 4121 O OG1 . THR A 1 512 ? 62.394 97.556 0.324 1.00 37.84 ? 512 THR A OG1 1 ATOM 4122 C CG2 . THR A 1 512 ? 62.433 95.744 1.855 1.00 33.87 ? 512 THR A CG2 1 ATOM 4123 N N . LYS A 1 513 ? 63.912 99.721 3.462 1.00 33.28 ? 513 LYS A N 1 ATOM 4124 C CA . LYS A 1 513 ? 64.839 100.850 3.374 1.00 33.64 ? 513 LYS A CA 1 ATOM 4125 C C . LYS A 1 513 ? 64.122 102.165 3.476 1.00 32.96 ? 513 LYS A C 1 ATOM 4126 O O . LYS A 1 513 ? 64.149 102.994 2.543 1.00 33.39 ? 513 LYS A O 1 ATOM 4127 C CB . LYS A 1 513 ? 65.707 100.751 2.107 1.00 34.14 ? 513 LYS A CB 1 ATOM 4128 C CG . LYS A 1 513 ? 66.656 99.512 2.083 1.00 35.88 ? 513 LYS A CG 1 ATOM 4129 C CD . LYS A 1 513 ? 67.368 99.312 0.697 1.00 37.90 ? 513 LYS A CD 1 ATOM 4130 C CE . LYS A 1 513 ? 68.044 97.927 0.628 1.00 42.78 ? 513 LYS A CE 1 ATOM 4131 N NZ . LYS A 1 513 ? 68.989 97.832 -0.521 1.00 45.19 ? 513 LYS A NZ 1 ATOM 4132 N N . LEU A 1 514 ? 63.427 102.342 4.608 1.00 32.96 ? 514 LEU A N 1 ATOM 4133 C CA . LEU A 1 514 ? 62.735 103.597 4.929 1.00 32.57 ? 514 LEU A CA 1 ATOM 4134 C C . LEU A 1 514 ? 63.680 104.790 4.752 1.00 33.60 ? 514 LEU A C 1 ATOM 4135 O O . LEU A 1 514 ? 64.769 104.786 5.317 1.00 32.66 ? 514 LEU A O 1 ATOM 4136 C CB . LEU A 1 514 ? 62.244 103.551 6.378 1.00 31.90 ? 514 LEU A CB 1 ATOM 4137 C CG . LEU A 1 514 ? 61.412 104.743 6.916 1.00 32.37 ? 514 LEU A CG 1 ATOM 4138 C CD1 . LEU A 1 514 ? 60.134 104.951 6.083 1.00 30.46 ? 514 LEU A CD1 1 ATOM 4139 C CD2 . LEU A 1 514 ? 61.025 104.542 8.419 1.00 30.99 ? 514 LEU A CD2 1 ATOM 4140 N N . ARG A 1 515 ? 63.263 105.799 3.997 1.00 35.47 ? 515 ARG A N 1 ATOM 4141 C CA . ARG A 1 515 ? 64.028 107.064 3.846 1.00 37.92 ? 515 ARG A CA 1 ATOM 4142 C C . ARG A 1 515 ? 65.466 106.874 3.392 1.00 38.38 ? 515 ARG A C 1 ATOM 4143 O O . ARG A 1 515 ? 66.366 107.591 3.857 1.00 38.01 ? 515 ARG A O 1 ATOM 4144 C CB . ARG A 1 515 ? 64.065 107.877 5.159 1.00 38.00 ? 515 ARG A CB 1 ATOM 4145 C CG . ARG A 1 515 ? 62.716 108.301 5.716 1.00 40.14 ? 515 ARG A CG 1 ATOM 4146 C CD . ARG A 1 515 ? 62.136 109.541 5.092 1.00 42.18 ? 515 ARG A CD 1 ATOM 4147 N NE . ARG A 1 515 ? 61.067 110.126 5.893 1.00 41.71 ? 515 ARG A NE 1 ATOM 4148 C CZ . ARG A 1 515 ? 59.846 109.600 6.046 1.00 45.05 ? 515 ARG A CZ 1 ATOM 4149 N NH1 . ARG A 1 515 ? 58.914 110.211 6.811 1.00 39.90 ? 515 ARG A NH1 1 ATOM 4150 N NH2 . ARG A 1 515 ? 59.537 108.464 5.424 1.00 46.42 ? 515 ARG A NH2 1 ATOM 4151 N N . ALA A 1 516 ? 65.688 105.898 2.516 1.00 39.03 ? 516 ALA A N 1 ATOM 4152 C CA . ALA A 1 516 ? 67.032 105.512 2.151 1.00 40.43 ? 516 ALA A CA 1 ATOM 4153 C C . ALA A 1 516 ? 67.859 106.762 1.741 1.00 41.06 ? 516 ALA A C 1 ATOM 4154 O O . ALA A 1 516 ? 68.944 107.004 2.286 1.00 39.76 ? 516 ALA A O 1 ATOM 4155 C CB . ALA A 1 516 ? 66.999 104.461 1.032 1.00 39.99 ? 516 ALA A CB 1 ATOM 4156 N N . GLN A 1 517 ? 67.322 107.565 0.822 1.00 42.42 ? 517 GLN A N 1 ATOM 4157 C CA . GLN A 1 517 ? 68.072 108.719 0.278 1.00 44.19 ? 517 GLN A CA 1 ATOM 4158 C C . GLN A 1 517 ? 68.335 109.826 1.304 1.00 42.94 ? 517 GLN A C 1 ATOM 4159 O O . GLN A 1 517 ? 69.405 110.406 1.339 1.00 42.31 ? 517 GLN A O 1 ATOM 4160 C CB . GLN A 1 517 ? 67.316 109.321 -0.901 1.00 45.80 ? 517 GLN A CB 1 ATOM 4161 C CG . GLN A 1 517 ? 67.733 108.778 -2.223 1.00 52.25 ? 517 GLN A CG 1 ATOM 4162 C CD . GLN A 1 517 ? 67.288 109.683 -3.356 1.00 60.11 ? 517 GLN A CD 1 ATOM 4163 O OE1 . GLN A 1 517 ? 68.128 110.310 -4.023 1.00 62.41 ? 517 GLN A OE1 1 ATOM 4164 N NE2 . GLN A 1 517 ? 65.965 109.773 -3.569 1.00 62.05 ? 517 GLN A NE2 1 ATOM 4165 N N . GLN A 1 518 ? 67.339 110.085 2.149 1.00 41.98 ? 518 GLN A N 1 ATOM 4166 C CA . GLN A 1 518 ? 67.407 111.124 3.159 1.00 40.37 ? 518 GLN A CA 1 ATOM 4167 C C . GLN A 1 518 ? 68.403 110.819 4.227 1.00 40.23 ? 518 GLN A C 1 ATOM 4168 O O . GLN A 1 518 ? 69.147 111.705 4.690 1.00 40.96 ? 518 GLN A O 1 ATOM 4169 C CB . GLN A 1 518 ? 66.029 111.284 3.795 1.00 40.19 ? 518 GLN A CB 1 ATOM 4170 C CG . GLN A 1 518 ? 64.998 111.820 2.826 1.00 40.45 ? 518 GLN A CG 1 ATOM 4171 C CD . GLN A 1 518 ? 64.168 110.734 2.132 1.00 41.90 ? 518 GLN A CD 1 ATOM 4172 O OE1 . GLN A 1 518 ? 63.010 110.963 1.803 1.00 45.79 ? 518 GLN A OE1 1 ATOM 4173 N NE2 . GLN A 1 518 ? 64.752 109.579 1.893 1.00 43.91 ? 518 GLN A NE2 1 ATOM 4174 N N . CYS A 1 519 ? 68.413 109.570 4.672 1.00 39.76 ? 519 CYS A N 1 ATOM 4175 C CA . CYS A 1 519 ? 69.255 109.182 5.788 1.00 39.84 ? 519 CYS A CA 1 ATOM 4176 C C . CYS A 1 519 ? 70.728 109.068 5.409 1.00 39.95 ? 519 CYS A C 1 ATOM 4177 O O . CYS A 1 519 ? 71.595 109.377 6.236 1.00 39.30 ? 519 CYS A O 1 ATOM 4178 C CB . CYS A 1 519 ? 68.684 107.917 6.442 1.00 40.11 ? 519 CYS A CB 1 ATOM 4179 S SG . CYS A 1 519 ? 67.086 108.307 7.249 1.00 44.27 ? 519 CYS A SG 1 ATOM 4180 N N . ARG A 1 520 ? 71.014 108.668 4.148 1.00 39.61 ? 520 ARG A N 1 ATOM 4181 C CA . ARG A 1 520 ? 72.376 108.727 3.621 1.00 40.25 ? 520 ARG A CA 1 ATOM 4182 C C . ARG A 1 520 ? 72.899 110.159 3.783 1.00 38.77 ? 520 ARG A C 1 ATOM 4183 O O . ARG A 1 520 ? 74.014 110.365 4.171 1.00 38.05 ? 520 ARG A O 1 ATOM 4184 C CB . ARG A 1 520 ? 72.456 108.268 2.127 1.00 41.01 ? 520 ARG A CB 1 ATOM 4185 C CG . ARG A 1 520 ? 72.475 106.691 1.927 1.00 46.87 ? 520 ARG A CG 1 ATOM 4186 C CD . ARG A 1 520 ? 72.638 106.143 0.433 1.00 50.06 ? 520 ARG A CD 1 ATOM 4187 N NE . ARG A 1 520 ? 71.398 105.558 -0.149 1.00 54.89 ? 520 ARG A NE 1 ATOM 4188 C CZ . ARG A 1 520 ? 70.663 106.111 -1.130 1.00 54.66 ? 520 ARG A CZ 1 ATOM 4189 N NH1 . ARG A 1 520 ? 69.565 105.498 -1.578 1.00 55.57 ? 520 ARG A NH1 1 ATOM 4190 N NH2 . ARG A 1 520 ? 71.017 107.282 -1.672 1.00 58.31 ? 520 ARG A NH2 1 ATOM 4191 N N . PHE A 1 521 ? 72.061 111.145 3.483 1.00 38.82 ? 521 PHE A N 1 ATOM 4192 C CA . PHE A 1 521 ? 72.415 112.555 3.691 1.00 38.92 ? 521 PHE A CA 1 ATOM 4193 C C . PHE A 1 521 ? 72.706 112.906 5.170 1.00 39.17 ? 521 PHE A C 1 ATOM 4194 O O . PHE A 1 521 ? 73.772 113.426 5.497 1.00 38.82 ? 521 PHE A O 1 ATOM 4195 C CB . PHE A 1 521 ? 71.350 113.497 3.056 1.00 37.87 ? 521 PHE A CB 1 ATOM 4196 C CG . PHE A 1 521 ? 71.525 114.926 3.470 1.00 40.37 ? 521 PHE A CG 1 ATOM 4197 C CD1 . PHE A 1 521 ? 72.501 115.741 2.843 1.00 38.18 ? 521 PHE A CD1 1 ATOM 4198 C CD2 . PHE A 1 521 ? 70.773 115.457 4.535 1.00 40.26 ? 521 PHE A CD2 1 ATOM 4199 C CE1 . PHE A 1 521 ? 72.709 117.062 3.269 1.00 36.85 ? 521 PHE A CE1 1 ATOM 4200 C CE2 . PHE A 1 521 ? 70.978 116.792 4.963 1.00 40.53 ? 521 PHE A CE2 1 ATOM 4201 C CZ . PHE A 1 521 ? 71.955 117.588 4.321 1.00 40.17 ? 521 PHE A CZ 1 ATOM 4202 N N . TRP A 1 522 ? 71.771 112.599 6.067 1.00 39.83 ? 522 TRP A N 1 ATOM 4203 C CA . TRP A 1 522 ? 71.933 112.941 7.491 1.00 40.79 ? 522 TRP A CA 1 ATOM 4204 C C . TRP A 1 522 ? 73.025 112.134 8.188 1.00 43.71 ? 522 TRP A C 1 ATOM 4205 O O . TRP A 1 522 ? 73.733 112.608 9.082 1.00 43.58 ? 522 TRP A O 1 ATOM 4206 C CB . TRP A 1 522 ? 70.588 112.769 8.238 1.00 39.01 ? 522 TRP A CB 1 ATOM 4207 C CG . TRP A 1 522 ? 69.595 113.782 7.820 1.00 35.36 ? 522 TRP A CG 1 ATOM 4208 C CD1 . TRP A 1 522 ? 68.456 113.563 7.085 1.00 35.53 ? 522 TRP A CD1 1 ATOM 4209 C CD2 . TRP A 1 522 ? 69.667 115.197 8.036 1.00 34.21 ? 522 TRP A CD2 1 ATOM 4210 N NE1 . TRP A 1 522 ? 67.813 114.749 6.833 1.00 36.51 ? 522 TRP A NE1 1 ATOM 4211 C CE2 . TRP A 1 522 ? 68.531 115.775 7.411 1.00 36.84 ? 522 TRP A CE2 1 ATOM 4212 C CE3 . TRP A 1 522 ? 70.586 116.046 8.680 1.00 33.97 ? 522 TRP A CE3 1 ATOM 4213 C CZ2 . TRP A 1 522 ? 68.279 117.171 7.421 1.00 34.97 ? 522 TRP A CZ2 1 ATOM 4214 C CZ3 . TRP A 1 522 ? 70.337 117.449 8.676 1.00 35.83 ? 522 TRP A CZ3 1 ATOM 4215 C CH2 . TRP A 1 522 ? 69.185 117.982 8.060 1.00 34.78 ? 522 TRP A CH2 1 ATOM 4216 N N . THR A 1 523 ? 73.144 110.878 7.784 1.00 46.90 ? 523 THR A N 1 ATOM 4217 C CA . THR A 1 523 ? 73.905 109.946 8.566 1.00 49.41 ? 523 THR A CA 1 ATOM 4218 C C . THR A 1 523 ? 75.334 109.955 8.075 1.00 51.51 ? 523 THR A C 1 ATOM 4219 O O . THR A 1 523 ? 76.254 109.947 8.881 1.00 52.29 ? 523 THR A O 1 ATOM 4220 C CB . THR A 1 523 ? 73.197 108.566 8.527 1.00 49.61 ? 523 THR A CB 1 ATOM 4221 O OG1 . THR A 1 523 ? 71.897 108.720 9.136 1.00 50.44 ? 523 THR A OG1 1 ATOM 4222 C CG2 . THR A 1 523 ? 73.870 107.535 9.428 1.00 49.88 ? 523 THR A CG2 1 ATOM 4223 N N . SER A 1 524 ? 75.533 110.037 6.764 1.00 53.69 ? 524 SER A N 1 ATOM 4224 C CA . SER A 1 524 ? 76.894 109.959 6.237 1.00 56.19 ? 524 SER A CA 1 ATOM 4225 C C . SER A 1 524 ? 77.468 111.319 6.042 1.00 56.83 ? 524 SER A C 1 ATOM 4226 O O . SER A 1 524 ? 78.502 111.628 6.654 1.00 59.59 ? 524 SER A O 1 ATOM 4227 C CB . SER A 1 524 ? 76.980 109.146 4.942 1.00 56.64 ? 524 SER A CB 1 ATOM 4228 O OG . SER A 1 524 ? 76.714 107.785 5.237 1.00 58.70 ? 524 SER A OG 1 ATOM 4229 N N . PHE A 1 525 ? 76.798 112.139 5.238 1.00 56.03 ? 525 PHE A N 1 ATOM 4230 C CA . PHE A 1 525 ? 77.298 113.465 4.923 1.00 56.03 ? 525 PHE A CA 1 ATOM 4231 C C . PHE A 1 525 ? 77.164 114.536 6.027 1.00 55.68 ? 525 PHE A C 1 ATOM 4232 O O . PHE A 1 525 ? 78.183 115.105 6.475 1.00 55.23 ? 525 PHE A O 1 ATOM 4233 C CB . PHE A 1 525 ? 76.675 114.030 3.659 1.00 55.62 ? 525 PHE A CB 1 ATOM 4234 C CG . PHE A 1 525 ? 77.089 115.445 3.405 1.00 59.35 ? 525 PHE A CG 1 ATOM 4235 C CD1 . PHE A 1 525 ? 76.145 116.445 3.230 1.00 60.45 ? 525 PHE A CD1 1 ATOM 4236 C CD2 . PHE A 1 525 ? 78.459 115.795 3.397 1.00 61.53 ? 525 PHE A CD2 1 ATOM 4237 C CE1 . PHE A 1 525 ? 76.541 117.766 3.026 1.00 60.18 ? 525 PHE A CE1 1 ATOM 4238 C CE2 . PHE A 1 525 ? 78.866 117.105 3.203 1.00 59.58 ? 525 PHE A CE2 1 ATOM 4239 C CZ . PHE A 1 525 ? 77.893 118.095 3.021 1.00 61.86 ? 525 PHE A CZ 1 ATOM 4240 N N . PHE A 1 526 ? 75.924 114.848 6.426 1.00 54.15 ? 526 PHE A N 1 ATOM 4241 C CA . PHE A 1 526 ? 75.705 115.962 7.358 1.00 53.12 ? 526 PHE A CA 1 ATOM 4242 C C . PHE A 1 526 ? 76.642 116.048 8.600 1.00 53.06 ? 526 PHE A C 1 ATOM 4243 O O . PHE A 1 526 ? 77.016 117.147 8.957 1.00 52.07 ? 526 PHE A O 1 ATOM 4244 C CB . PHE A 1 526 ? 74.220 116.133 7.753 1.00 51.62 ? 526 PHE A CB 1 ATOM 4245 C CG . PHE A 1 526 ? 73.922 117.454 8.454 1.00 49.22 ? 526 PHE A CG 1 ATOM 4246 C CD1 . PHE A 1 526 ? 73.761 118.633 7.723 1.00 47.52 ? 526 PHE A CD1 1 ATOM 4247 C CD2 . PHE A 1 526 ? 73.852 117.526 9.838 1.00 47.43 ? 526 PHE A CD2 1 ATOM 4248 C CE1 . PHE A 1 526 ? 73.503 119.829 8.351 1.00 46.30 ? 526 PHE A CE1 1 ATOM 4249 C CE2 . PHE A 1 526 ? 73.579 118.736 10.479 1.00 46.76 ? 526 PHE A CE2 1 ATOM 4250 C CZ . PHE A 1 526 ? 73.389 119.874 9.739 1.00 46.93 ? 526 PHE A CZ 1 ATOM 4251 N N . PRO A 1 527 ? 77.004 114.935 9.259 1.00 54.32 ? 527 PRO A N 1 ATOM 4252 C CA . PRO A 1 527 ? 77.856 115.009 10.456 1.00 56.00 ? 527 PRO A CA 1 ATOM 4253 C C . PRO A 1 527 ? 79.237 115.616 10.179 1.00 57.52 ? 527 PRO A C 1 ATOM 4254 O O . PRO A 1 527 ? 79.965 115.934 11.121 1.00 57.29 ? 527 PRO A O 1 ATOM 4255 C CB . PRO A 1 527 ? 78.011 113.541 10.892 1.00 55.85 ? 527 PRO A CB 1 ATOM 4256 C CG . PRO A 1 527 ? 76.928 112.801 10.210 1.00 55.43 ? 527 PRO A CG 1 ATOM 4257 C CD . PRO A 1 527 ? 76.630 113.541 8.959 1.00 54.63 ? 527 PRO A CD 1 ATOM 4258 N N . LYS A 1 528 ? 79.573 115.774 8.897 1.00 59.06 ? 528 LYS A N 1 ATOM 4259 C CA . LYS A 1 528 ? 80.847 116.358 8.507 1.00 60.67 ? 528 LYS A CA 1 ATOM 4260 C C . LYS A 1 528 ? 80.845 117.887 8.566 1.00 61.42 ? 528 LYS A C 1 ATOM 4261 O O . LYS A 1 528 ? 81.866 118.493 8.930 1.00 62.17 ? 528 LYS A O 1 ATOM 4262 C CB . LYS A 1 528 ? 81.271 115.851 7.128 1.00 60.32 ? 528 LYS A CB 1 ATOM 4263 C CG . LYS A 1 528 ? 81.724 114.399 7.154 1.00 60.94 ? 528 LYS A CG 1 ATOM 4264 C CD . LYS A 1 528 ? 81.630 113.748 5.786 1.00 62.54 ? 528 LYS A CD 1 ATOM 4265 C CE . LYS A 1 528 ? 81.820 112.259 5.928 1.00 64.17 ? 528 LYS A CE 1 ATOM 4266 N NZ . LYS A 1 528 ? 81.208 111.553 4.793 1.00 65.58 ? 528 LYS A NZ 1 ATOM 4267 N N . VAL A 1 529 ? 79.710 118.511 8.243 1.00 61.46 ? 529 VAL A N 1 ATOM 4268 C CA . VAL A 1 529 ? 79.628 119.984 8.245 1.00 61.56 ? 529 VAL A CA 1 ATOM 4269 C C . VAL A 1 529 ? 79.890 120.595 9.651 1.00 61.98 ? 529 VAL A C 1 ATOM 4270 O O . VAL A 1 529 ? 79.807 119.941 10.712 1.00 61.55 ? 529 VAL A O 1 ATOM 4271 C CB . VAL A 1 529 ? 78.297 120.529 7.579 1.00 61.79 ? 529 VAL A CB 1 ATOM 4272 C CG1 . VAL A 1 529 ? 77.971 119.772 6.299 1.00 59.87 ? 529 VAL A CG1 1 ATOM 4273 C CG2 . VAL A 1 529 ? 77.098 120.501 8.547 1.00 60.00 ? 529 VAL A CG2 1 ATOM 4274 O OXT . VAL A 1 529 ? 80.211 121.777 9.765 1.00 62.31 ? 529 VAL A OXT 1 HETATM 4275 C C1 . NAG B 2 . ? 79.152 129.342 26.665 1.00 77.58 ? 530 NAG A C1 1 HETATM 4276 C C2 . NAG B 2 . ? 78.781 129.480 25.183 1.00 81.74 ? 530 NAG A C2 1 HETATM 4277 C C3 . NAG B 2 . ? 78.960 130.916 24.672 1.00 81.91 ? 530 NAG A C3 1 HETATM 4278 C C4 . NAG B 2 . ? 78.400 131.987 25.614 1.00 82.25 ? 530 NAG A C4 1 HETATM 4279 C C5 . NAG B 2 . ? 78.768 131.678 27.072 1.00 81.09 ? 530 NAG A C5 1 HETATM 4280 C C6 . NAG B 2 . ? 78.095 132.592 28.108 1.00 80.12 ? 530 NAG A C6 1 HETATM 4281 C C7 . NAG B 2 . ? 79.159 127.410 23.912 1.00 86.18 ? 530 NAG A C7 1 HETATM 4282 C C8 . NAG B 2 . ? 79.855 126.192 24.462 1.00 87.07 ? 530 NAG A C8 1 HETATM 4283 N N2 . NAG B 2 . ? 79.593 128.589 24.369 1.00 84.34 ? 530 NAG A N2 1 HETATM 4284 O O3 . NAG B 2 . ? 78.381 131.076 23.387 1.00 81.65 ? 530 NAG A O3 1 HETATM 4285 O O4 . NAG B 2 . ? 78.954 133.245 25.251 1.00 84.52 ? 530 NAG A O4 1 HETATM 4286 O O5 . NAG B 2 . ? 78.442 130.334 27.384 1.00 80.37 ? 530 NAG A O5 1 HETATM 4287 O O6 . NAG B 2 . ? 77.236 133.561 27.530 1.00 80.28 ? 530 NAG A O6 1 HETATM 4288 O O7 . NAG B 2 . ? 78.245 127.295 23.090 1.00 86.11 ? 530 NAG A O7 1 HETATM 4289 C C1 . NAG C 2 . ? 78.117 134.031 24.370 1.00 85.53 ? 531 NAG A C1 1 HETATM 4290 C C2 . NAG C 2 . ? 78.420 135.528 24.522 1.00 86.14 ? 531 NAG A C2 1 HETATM 4291 C C3 . NAG C 2 . ? 77.387 136.300 23.691 1.00 87.25 ? 531 NAG A C3 1 HETATM 4292 C C4 . NAG C 2 . ? 77.581 135.902 22.221 1.00 87.70 ? 531 NAG A C4 1 HETATM 4293 C C5 . NAG C 2 . ? 77.494 134.374 22.060 1.00 87.47 ? 531 NAG A C5 1 HETATM 4294 C C6 . NAG C 2 . ? 77.967 133.940 20.677 1.00 88.14 ? 531 NAG A C6 1 HETATM 4295 C C7 . NAG C 2 . ? 79.656 135.998 26.608 1.00 83.19 ? 531 NAG A C7 1 HETATM 4296 C C8 . NAG C 2 . ? 79.537 136.541 28.001 1.00 82.29 ? 531 NAG A C8 1 HETATM 4297 N N2 . NAG C 2 . ? 78.501 135.954 25.914 1.00 84.32 ? 531 NAG A N2 1 HETATM 4298 O O3 . NAG C 2 . ? 77.535 137.699 23.828 1.00 88.11 ? 531 NAG A O3 1 HETATM 4299 O O4 . NAG C 2 . ? 76.676 136.596 21.375 1.00 87.09 ? 531 NAG A O4 1 HETATM 4300 O O5 . NAG C 2 . ? 78.297 133.672 23.008 1.00 86.57 ? 531 NAG A O5 1 HETATM 4301 O O6 . NAG C 2 . ? 76.851 133.927 19.815 1.00 88.85 ? 531 NAG A O6 1 HETATM 4302 O O7 . NAG C 2 . ? 80.766 135.631 26.196 1.00 79.49 ? 531 NAG A O7 1 HETATM 4303 C C1 . FUL D 3 . ? 75.926 133.441 28.115 1.00 80.29 ? 532 FUL A C1 1 HETATM 4304 C C2 . FUL D 3 . ? 74.780 134.018 27.289 1.00 80.13 ? 532 FUL A C2 1 HETATM 4305 O O2 . FUL D 3 . ? 74.969 133.903 25.898 1.00 81.21 ? 532 FUL A O2 1 HETATM 4306 C C3 . FUL D 3 . ? 73.605 133.154 27.731 1.00 80.34 ? 532 FUL A C3 1 HETATM 4307 O O3 . FUL D 3 . ? 72.439 133.408 26.969 1.00 81.49 ? 532 FUL A O3 1 HETATM 4308 C C4 . FUL D 3 . ? 73.383 133.320 29.245 1.00 79.97 ? 532 FUL A C4 1 HETATM 4309 O O4 . FUL D 3 . ? 72.717 134.542 29.485 1.00 80.13 ? 532 FUL A O4 1 HETATM 4310 C C5 . FUL D 3 . ? 74.705 133.168 30.044 1.00 79.19 ? 532 FUL A C5 1 HETATM 4311 C C6 . FUL D 3 . ? 74.599 133.505 31.530 1.00 79.08 ? 532 FUL A C6 1 HETATM 4312 O O5 . FUL D 3 . ? 75.767 133.900 29.449 1.00 79.15 ? 532 FUL A O5 1 HETATM 4313 C C1 . NAG E 2 . ? 49.562 131.552 8.984 1.00 56.20 ? 533 NAG A C1 1 HETATM 4314 C C2 . NAG E 2 . ? 49.682 132.547 7.809 1.00 60.76 ? 533 NAG A C2 1 HETATM 4315 C C3 . NAG E 2 . ? 50.969 133.348 7.918 1.00 61.43 ? 533 NAG A C3 1 HETATM 4316 C C4 . NAG E 2 . ? 51.189 133.921 9.317 1.00 63.12 ? 533 NAG A C4 1 HETATM 4317 C C5 . NAG E 2 . ? 50.887 132.925 10.436 1.00 60.99 ? 533 NAG A C5 1 HETATM 4318 C C6 . NAG E 2 . ? 50.881 133.596 11.825 1.00 62.69 ? 533 NAG A C6 1 HETATM 4319 C C7 . NAG E 2 . ? 48.783 131.559 5.681 1.00 64.73 ? 533 NAG A C7 1 HETATM 4320 C C8 . NAG E 2 . ? 47.371 132.011 5.909 1.00 64.11 ? 533 NAG A C8 1 HETATM 4321 N N2 . NAG E 2 . ? 49.767 131.961 6.493 1.00 61.05 ? 533 NAG A N2 1 HETATM 4322 O O3 . NAG E 2 . ? 50.901 134.393 6.986 1.00 60.19 ? 533 NAG A O3 1 HETATM 4323 O O4 . NAG E 2 . ? 52.514 134.388 9.413 1.00 67.51 ? 533 NAG A O4 1 HETATM 4324 O O5 . NAG E 2 . ? 49.649 132.279 10.190 1.00 57.26 ? 533 NAG A O5 1 HETATM 4325 O O6 . NAG E 2 . ? 49.659 134.264 12.107 1.00 66.91 ? 533 NAG A O6 1 HETATM 4326 O O7 . NAG E 2 . ? 49.022 130.811 4.724 1.00 66.54 ? 533 NAG A O7 1 HETATM 4327 C C1 . NAG F 2 . ? 52.419 135.809 9.587 1.00 73.92 ? 534 NAG A C1 1 HETATM 4328 C C2 . NAG F 2 . ? 53.680 136.282 10.280 1.00 76.47 ? 534 NAG A C2 1 HETATM 4329 C C3 . NAG F 2 . ? 53.582 137.768 10.584 1.00 77.54 ? 534 NAG A C3 1 HETATM 4330 C C4 . NAG F 2 . ? 53.086 138.613 9.385 1.00 77.96 ? 534 NAG A C4 1 HETATM 4331 C C5 . NAG F 2 . ? 52.366 137.896 8.226 1.00 77.84 ? 534 NAG A C5 1 HETATM 4332 C C6 . NAG F 2 . ? 53.101 138.205 6.911 1.00 78.11 ? 534 NAG A C6 1 HETATM 4333 C C7 . NAG F 2 . ? 54.887 134.573 11.556 1.00 81.28 ? 534 NAG A C7 1 HETATM 4334 C C8 . NAG F 2 . ? 55.187 133.956 12.902 1.00 80.21 ? 534 NAG A C8 1 HETATM 4335 N N2 . NAG F 2 . ? 53.924 135.513 11.490 1.00 78.78 ? 534 NAG A N2 1 HETATM 4336 O O3 . NAG F 2 . ? 54.887 138.165 10.958 1.00 77.15 ? 534 NAG A O3 1 HETATM 4337 O O4 . NAG F 2 . ? 52.202 139.628 9.804 1.00 76.72 ? 534 NAG A O4 1 HETATM 4338 O O5 . NAG F 2 . ? 52.160 136.479 8.354 1.00 76.92 ? 534 NAG A O5 1 HETATM 4339 O O6 . NAG F 2 . ? 53.698 137.054 6.331 1.00 77.02 ? 534 NAG A O6 1 HETATM 4340 O O7 . NAG F 2 . ? 55.534 134.193 10.571 1.00 82.32 ? 534 NAG A O7 1 HETATM 4341 C C1 . NAG G 2 . ? 58.224 82.890 36.550 1.00 62.52 ? 535 NAG A C1 1 HETATM 4342 C C2 . NAG G 2 . ? 58.498 81.893 37.702 1.00 67.32 ? 535 NAG A C2 1 HETATM 4343 C C3 . NAG G 2 . ? 60.002 81.592 37.808 1.00 67.95 ? 535 NAG A C3 1 HETATM 4344 C C4 . NAG G 2 . ? 60.538 81.122 36.451 1.00 68.67 ? 535 NAG A C4 1 HETATM 4345 C C5 . NAG G 2 . ? 60.192 82.210 35.401 1.00 68.02 ? 535 NAG A C5 1 HETATM 4346 C C6 . NAG G 2 . ? 60.773 81.993 33.996 1.00 68.23 ? 535 NAG A C6 1 HETATM 4347 C C7 . NAG G 2 . ? 56.763 81.953 39.510 1.00 70.02 ? 535 NAG A C7 1 HETATM 4348 C C8 . NAG G 2 . ? 55.721 81.251 38.671 1.00 69.90 ? 535 NAG A C8 1 HETATM 4349 N N2 . NAG G 2 . ? 57.942 82.339 38.985 1.00 68.25 ? 535 NAG A N2 1 HETATM 4350 O O3 . NAG G 2 . ? 60.301 80.651 38.824 1.00 69.46 ? 535 NAG A O3 1 HETATM 4351 O O4 . NAG G 2 . ? 61.928 80.855 36.579 1.00 69.82 ? 535 NAG A O4 1 HETATM 4352 O O5 . NAG G 2 . ? 58.769 82.385 35.337 1.00 64.94 ? 535 NAG A O5 1 HETATM 4353 O O6 . NAG G 2 . ? 60.810 83.200 33.258 1.00 68.09 ? 535 NAG A O6 1 HETATM 4354 O O7 . NAG G 2 . ? 56.506 82.159 40.695 1.00 72.03 ? 535 NAG A O7 1 HETATM 4355 C C1 . NAG H 2 . ? 44.790 105.230 53.952 1.00 72.59 ? 536 NAG A C1 1 HETATM 4356 C C2 . NAG H 2 . ? 44.529 106.193 55.122 1.00 76.64 ? 536 NAG A C2 1 HETATM 4357 C C3 . NAG H 2 . ? 43.668 105.547 56.220 1.00 77.79 ? 536 NAG A C3 1 HETATM 4358 C C4 . NAG H 2 . ? 42.369 105.057 55.572 1.00 78.39 ? 536 NAG A C4 1 HETATM 4359 C C5 . NAG H 2 . ? 42.731 104.082 54.443 1.00 78.03 ? 536 NAG A C5 1 HETATM 4360 C C6 . NAG H 2 . ? 41.505 103.358 53.853 1.00 78.56 ? 536 NAG A C6 1 HETATM 4361 C C7 . NAG H 2 . ? 46.077 108.059 55.543 1.00 76.05 ? 536 NAG A C7 1 HETATM 4362 C C8 . NAG H 2 . ? 45.006 109.069 55.192 1.00 76.46 ? 536 NAG A C8 1 HETATM 4363 N N2 . NAG H 2 . ? 45.756 106.763 55.657 1.00 75.29 ? 536 NAG A N2 1 HETATM 4364 O O3 . NAG H 2 . ? 43.389 106.490 57.229 1.00 78.96 ? 536 NAG A O3 1 HETATM 4365 O O4 . NAG H 2 . ? 41.487 104.466 56.500 1.00 79.09 ? 536 NAG A O4 1 HETATM 4366 O O5 . NAG H 2 . ? 43.526 104.773 53.464 1.00 75.79 ? 536 NAG A O5 1 HETATM 4367 O O6 . NAG H 2 . ? 40.440 104.227 53.519 1.00 79.23 ? 536 NAG A O6 1 HETATM 4368 O O7 . NAG H 2 . ? 47.235 108.440 55.725 1.00 76.18 ? 536 NAG A O7 1 HETATM 4369 C C1 . NAG I 2 . ? 40.908 89.097 16.208 1.00 71.48 ? 537 NAG A C1 1 HETATM 4370 C C2 . NAG I 2 . ? 41.130 90.145 17.319 1.00 72.75 ? 537 NAG A C2 1 HETATM 4371 C C3 . NAG I 2 . ? 39.872 90.327 18.198 1.00 75.11 ? 537 NAG A C3 1 HETATM 4372 C C4 . NAG I 2 . ? 38.583 90.472 17.364 1.00 77.69 ? 537 NAG A C4 1 HETATM 4373 C C5 . NAG I 2 . ? 38.536 89.417 16.236 1.00 78.36 ? 537 NAG A C5 1 HETATM 4374 C C6 . NAG I 2 . ? 37.299 89.532 15.324 1.00 80.05 ? 537 NAG A C6 1 HETATM 4375 C C7 . NAG I 2 . ? 43.439 90.665 18.025 1.00 66.24 ? 537 NAG A C7 1 HETATM 4376 C C8 . NAG I 2 . ? 44.523 90.358 19.016 1.00 64.06 ? 537 NAG A C8 1 HETATM 4377 N N2 . NAG I 2 . ? 42.337 89.883 18.099 1.00 68.37 ? 537 NAG A N2 1 HETATM 4378 O O3 . NAG I 2 . ? 39.977 91.484 19.000 1.00 75.46 ? 537 NAG A O3 1 HETATM 4379 O O4 . NAG I 2 . ? 37.451 90.400 18.228 1.00 78.46 ? 537 NAG A O4 1 HETATM 4380 O O5 . NAG I 2 . ? 39.745 89.499 15.473 1.00 76.17 ? 537 NAG A O5 1 HETATM 4381 O O6 . NAG I 2 . ? 37.133 88.379 14.512 1.00 80.79 ? 537 NAG A O6 1 HETATM 4382 O O7 . NAG I 2 . ? 43.621 91.597 17.221 1.00 63.11 ? 537 NAG A O7 1 HETATM 4383 S S . SO4 J 4 . ? 67.831 86.803 19.182 1.00 60.92 ? 601 SO4 A S 1 HETATM 4384 O O1 . SO4 J 4 . ? 67.531 86.059 20.394 1.00 58.52 ? 601 SO4 A O1 1 HETATM 4385 O O2 . SO4 J 4 . ? 67.777 88.259 19.455 1.00 58.86 ? 601 SO4 A O2 1 HETATM 4386 O O3 . SO4 J 4 . ? 66.846 86.454 18.164 1.00 59.83 ? 601 SO4 A O3 1 HETATM 4387 O O4 . SO4 J 4 . ? 69.172 86.429 18.697 1.00 57.68 ? 601 SO4 A O4 1 HETATM 4388 S S . SO4 K 4 . ? 74.377 112.179 -0.280 0.50 49.39 ? 602 SO4 A S 1 HETATM 4389 O O1 . SO4 K 4 . ? 75.666 112.024 0.406 0.50 48.83 ? 602 SO4 A O1 1 HETATM 4390 O O2 . SO4 K 4 . ? 74.190 111.111 -1.257 0.50 46.78 ? 602 SO4 A O2 1 HETATM 4391 O O3 . SO4 K 4 . ? 74.321 113.481 -0.966 0.50 48.61 ? 602 SO4 A O3 1 HETATM 4392 O O4 . SO4 K 4 . ? 73.307 112.103 0.697 0.50 46.84 ? 602 SO4 A O4 1 HETATM 4393 S S . SO4 L 4 . ? 68.456 131.346 -3.206 0.50 57.33 ? 603 SO4 A S 1 HETATM 4394 O O1 . SO4 L 4 . ? 68.684 129.907 -3.059 0.50 57.10 ? 603 SO4 A O1 1 HETATM 4395 O O2 . SO4 L 4 . ? 69.063 132.054 -2.080 0.50 52.19 ? 603 SO4 A O2 1 HETATM 4396 O O3 . SO4 L 4 . ? 67.014 131.593 -3.239 0.50 56.34 ? 603 SO4 A O3 1 HETATM 4397 O O4 . SO4 L 4 . ? 69.019 131.803 -4.473 0.50 55.92 ? 603 SO4 A O4 1 HETATM 4398 CL CL . CL M 5 . ? 46.993 93.173 8.644 1.00 63.44 ? 701 CL A CL 1 HETATM 4399 CL CL . CL N 5 . ? 55.941 108.885 3.707 1.00 73.17 ? 702 CL A CL 1 HETATM 4400 C C1 . ISP O 6 . ? 61.297 117.333 22.487 1.00 58.48 ? 1001 ISP A C1 1 HETATM 4401 C C2 . ISP O 6 . ? 62.139 116.264 21.805 1.00 56.54 ? 1001 ISP A C2 1 HETATM 4402 C C3 . ISP O 6 . ? 63.583 116.735 21.819 1.00 55.57 ? 1001 ISP A C3 1 HETATM 4403 P P . ISP O 6 . ? 60.827 114.077 22.943 1.00 56.56 ? 1001 ISP A P 1 HETATM 4404 O O1P . ISP O 6 . ? 62.098 115.037 22.521 1.00 56.33 ? 1001 ISP A O1P 1 HETATM 4405 O O3P . ISP O 6 . ? 59.550 114.836 22.598 1.00 54.55 ? 1001 ISP A O3P 1 HETATM 4406 O O4P . ISP O 6 . ? 61.039 113.789 24.431 1.00 47.31 ? 1001 ISP A O4P 1 HETATM 4407 C C1 . GOL P 7 . ? 70.965 120.093 21.980 1.00 62.24 ? 604 GOL A C1 1 HETATM 4408 O O1 . GOL P 7 . ? 70.659 121.397 22.373 1.00 62.10 ? 604 GOL A O1 1 HETATM 4409 C C2 . GOL P 7 . ? 71.925 119.565 23.031 1.00 63.55 ? 604 GOL A C2 1 HETATM 4410 O O2 . GOL P 7 . ? 73.159 119.339 22.378 1.00 68.62 ? 604 GOL A O2 1 HETATM 4411 C C3 . GOL P 7 . ? 71.379 118.235 23.571 1.00 61.71 ? 604 GOL A C3 1 HETATM 4412 O O3 . GOL P 7 . ? 71.500 118.174 24.979 1.00 57.19 ? 604 GOL A O3 1 HETATM 4413 C C1 . GOL Q 7 . ? 55.342 114.661 22.761 1.00 54.01 ? 605 GOL A C1 1 HETATM 4414 O O1 . GOL Q 7 . ? 54.893 115.923 22.332 1.00 58.37 ? 605 GOL A O1 1 HETATM 4415 C C2 . GOL Q 7 . ? 55.606 114.793 24.253 1.00 56.88 ? 605 GOL A C2 1 HETATM 4416 O O2 . GOL Q 7 . ? 56.673 115.675 24.511 1.00 57.85 ? 605 GOL A O2 1 HETATM 4417 C C3 . GOL Q 7 . ? 55.939 113.430 24.836 1.00 56.93 ? 605 GOL A C3 1 HETATM 4418 O O3 . GOL Q 7 . ? 57.241 113.063 24.439 1.00 59.08 ? 605 GOL A O3 1 HETATM 4419 C C1 . GOL R 7 . ? 44.378 105.238 36.238 1.00 52.88 ? 606 GOL A C1 1 HETATM 4420 O O1 . GOL R 7 . ? 44.383 103.921 35.689 1.00 49.94 ? 606 GOL A O1 1 HETATM 4421 C C2 . GOL R 7 . ? 42.939 105.710 36.429 1.00 54.79 ? 606 GOL A C2 1 HETATM 4422 O O2 . GOL R 7 . ? 42.239 105.688 35.197 1.00 55.15 ? 606 GOL A O2 1 HETATM 4423 C C3 . GOL R 7 . ? 42.948 107.128 36.964 1.00 57.89 ? 606 GOL A C3 1 HETATM 4424 O O3 . GOL R 7 . ? 42.769 106.984 38.345 1.00 62.55 ? 606 GOL A O3 1 HETATM 4425 C C1 . GOL S 7 . ? 45.072 113.298 21.083 1.00 55.34 ? 607 GOL A C1 1 HETATM 4426 O O1 . GOL S 7 . ? 45.226 112.292 22.026 1.00 55.84 ? 607 GOL A O1 1 HETATM 4427 C C2 . GOL S 7 . ? 43.616 113.471 20.722 1.00 60.06 ? 607 GOL A C2 1 HETATM 4428 O O2 . GOL S 7 . ? 42.660 113.066 21.711 1.00 59.82 ? 607 GOL A O2 1 HETATM 4429 C C3 . GOL S 7 . ? 43.462 112.767 19.391 1.00 60.88 ? 607 GOL A C3 1 HETATM 4430 O O3 . GOL S 7 . ? 43.741 111.397 19.484 1.00 61.67 ? 607 GOL A O3 1 HETATM 4431 O O . HOH T 8 . ? 61.343 95.018 10.901 1.00 32.69 ? 1102 HOH A O 1 HETATM 4432 O O . HOH T 8 . ? 55.219 116.010 14.710 1.00 31.89 ? 1103 HOH A O 1 HETATM 4433 O O . HOH T 8 . ? 55.695 112.972 28.942 1.00 26.04 ? 1104 HOH A O 1 HETATM 4434 O O . HOH T 8 . ? 73.597 114.915 32.716 1.00 30.42 ? 1105 HOH A O 1 HETATM 4435 O O . HOH T 8 . ? 57.589 106.883 32.978 1.00 32.81 ? 1106 HOH A O 1 HETATM 4436 O O . HOH T 8 . ? 56.346 110.073 25.879 1.00 36.23 ? 1107 HOH A O 1 HETATM 4437 O O . HOH T 8 . ? 61.743 113.765 29.474 1.00 31.45 ? 1108 HOH A O 1 HETATM 4438 O O . HOH T 8 . ? 56.608 105.980 17.150 1.00 28.61 ? 1109 HOH A O 1 HETATM 4439 O O . HOH T 8 . ? 55.887 120.568 31.334 1.00 37.75 ? 1110 HOH A O 1 HETATM 4440 O O . HOH T 8 . ? 65.198 92.783 7.255 1.00 35.13 ? 1111 HOH A O 1 HETATM 4441 O O . HOH T 8 . ? 65.501 117.837 43.642 1.00 38.14 ? 1112 HOH A O 1 HETATM 4442 O O . HOH T 8 . ? 57.297 114.000 36.491 1.00 33.44 ? 1113 HOH A O 1 HETATM 4443 O O . HOH T 8 . ? 77.893 99.516 27.223 1.00 37.90 ? 1114 HOH A O 1 HETATM 4444 O O . HOH T 8 . ? 71.072 109.988 11.589 1.00 31.51 ? 1115 HOH A O 1 HETATM 4445 O O . HOH T 8 . ? 69.972 106.576 9.155 1.00 39.77 ? 1116 HOH A O 1 HETATM 4446 O O . HOH T 8 . ? 56.203 109.544 18.968 1.00 27.69 ? 1117 HOH A O 1 HETATM 4447 O O . HOH T 8 . ? 63.101 95.665 36.601 1.00 33.22 ? 1118 HOH A O 1 HETATM 4448 O O . HOH T 8 . ? 80.326 123.230 7.248 1.00 66.38 ? 1119 HOH A O 1 HETATM 4449 O O . HOH T 8 . ? 65.680 108.714 17.207 1.00 36.82 ? 1120 HOH A O 1 HETATM 4450 O O . HOH T 8 . ? 74.213 118.146 45.893 1.00 61.15 ? 1121 HOH A O 1 HETATM 4451 O O . HOH T 8 . ? 47.944 109.593 15.043 1.00 46.20 ? 1122 HOH A O 1 HETATM 4452 O O . HOH T 8 . ? 51.985 105.779 33.150 1.00 31.41 ? 1123 HOH A O 1 HETATM 4453 O O . HOH T 8 . ? 60.006 109.300 47.047 1.00 43.03 ? 1124 HOH A O 1 HETATM 4454 O O . HOH T 8 . ? 73.359 118.122 31.218 1.00 41.64 ? 1125 HOH A O 1 HETATM 4455 O O . HOH T 8 . ? 63.718 102.536 -0.083 1.00 39.08 ? 1126 HOH A O 1 HETATM 4456 O O . HOH T 8 . ? 62.887 117.887 37.777 1.00 37.25 ? 1127 HOH A O 1 HETATM 4457 O O . HOH T 8 . ? 55.180 95.060 -0.006 1.00 44.54 ? 1128 HOH A O 1 HETATM 4458 O O . HOH T 8 . ? 48.929 107.722 33.380 1.00 36.21 ? 1129 HOH A O 1 HETATM 4459 O O . HOH T 8 . ? 53.311 93.470 2.489 1.00 40.67 ? 1130 HOH A O 1 HETATM 4460 O O . HOH T 8 . ? 73.316 112.543 20.532 1.00 49.11 ? 1131 HOH A O 1 HETATM 4461 O O . HOH T 8 . ? 46.944 100.877 28.923 1.00 36.87 ? 1132 HOH A O 1 HETATM 4462 O O . HOH T 8 . ? 59.960 128.598 8.324 1.00 46.46 ? 1133 HOH A O 1 HETATM 4463 O O . HOH T 8 . ? 52.810 120.531 24.967 1.00 37.38 ? 1134 HOH A O 1 HETATM 4464 O O . HOH T 8 . ? 64.199 100.330 6.635 1.00 31.04 ? 1135 HOH A O 1 HETATM 4465 O O . HOH T 8 . ? 67.640 91.618 13.336 1.00 39.78 ? 1136 HOH A O 1 HETATM 4466 O O . HOH T 8 . ? 55.207 120.029 7.167 1.00 40.85 ? 1137 HOH A O 1 HETATM 4467 O O . HOH T 8 . ? 72.521 92.521 18.618 1.00 42.27 ? 1138 HOH A O 1 HETATM 4468 O O . HOH T 8 . ? 39.971 105.574 11.139 1.00 50.40 ? 1139 HOH A O 1 HETATM 4469 O O . HOH T 8 . ? 52.662 111.995 38.635 1.00 40.72 ? 1140 HOH A O 1 HETATM 4470 O O . HOH T 8 . ? 84.574 106.364 35.903 1.00 55.06 ? 1141 HOH A O 1 HETATM 4471 O O . HOH T 8 . ? 68.189 119.077 17.215 1.00 39.78 ? 1142 HOH A O 1 HETATM 4472 O O . HOH T 8 . ? 49.107 109.752 21.764 1.00 38.56 ? 1143 HOH A O 1 HETATM 4473 O O . HOH T 8 . ? 53.095 113.071 45.969 1.00 47.02 ? 1144 HOH A O 1 HETATM 4474 O O . HOH T 8 . ? 49.216 95.506 13.499 1.00 46.27 ? 1145 HOH A O 1 HETATM 4475 O O . HOH T 8 . ? 77.916 109.423 39.168 1.00 36.38 ? 1146 HOH A O 1 HETATM 4476 O O . HOH T 8 . ? 63.329 116.720 42.097 1.00 37.74 ? 1147 HOH A O 1 HETATM 4477 O O . HOH T 8 . ? 70.445 112.505 12.289 1.00 39.63 ? 1148 HOH A O 1 HETATM 4478 O O . HOH T 8 . ? 51.973 88.991 12.892 1.00 51.25 ? 1149 HOH A O 1 HETATM 4479 O O . HOH T 8 . ? 76.562 110.488 37.318 1.00 37.94 ? 1150 HOH A O 1 HETATM 4480 O O . HOH T 8 . ? 52.530 130.630 5.806 1.00 45.17 ? 1151 HOH A O 1 HETATM 4481 O O . HOH T 8 . ? 60.269 111.826 46.182 1.00 38.11 ? 1152 HOH A O 1 HETATM 4482 O O . HOH T 8 . ? 49.289 86.779 23.413 1.00 38.11 ? 1153 HOH A O 1 HETATM 4483 O O . HOH T 8 . ? 67.122 110.766 47.054 1.00 45.58 ? 1154 HOH A O 1 HETATM 4484 O O . HOH T 8 . ? 59.718 90.966 28.898 1.00 38.32 ? 1155 HOH A O 1 HETATM 4485 O O . HOH T 8 . ? 67.118 103.657 5.594 1.00 40.24 ? 1156 HOH A O 1 HETATM 4486 O O . HOH T 8 . ? 60.611 102.316 1.933 1.00 37.11 ? 1157 HOH A O 1 HETATM 4487 O O . HOH T 8 . ? 64.740 96.777 -1.376 1.00 41.91 ? 1158 HOH A O 1 HETATM 4488 O O . HOH T 8 . ? 66.828 101.319 6.763 1.00 40.02 ? 1159 HOH A O 1 HETATM 4489 O O . HOH T 8 . ? 69.081 112.676 45.797 1.00 40.43 ? 1160 HOH A O 1 HETATM 4490 O O . HOH T 8 . ? 67.733 117.118 42.020 1.00 33.72 ? 1161 HOH A O 1 HETATM 4491 O O . HOH T 8 . ? 46.665 94.697 5.324 1.00 69.12 ? 1162 HOH A O 1 HETATM 4492 O O . HOH T 8 . ? 64.926 121.215 36.715 1.00 42.12 ? 1163 HOH A O 1 HETATM 4493 O O . HOH T 8 . ? 54.805 115.518 28.526 1.00 33.38 ? 1164 HOH A O 1 HETATM 4494 O O . HOH T 8 . ? 50.205 125.390 25.546 1.00 39.37 ? 1165 HOH A O 1 HETATM 4495 O O . HOH T 8 . ? 48.847 86.631 18.801 1.00 37.85 ? 1166 HOH A O 1 HETATM 4496 O O . HOH T 8 . ? 65.638 121.267 47.682 1.00 47.51 ? 1167 HOH A O 1 HETATM 4497 O O . HOH T 8 . ? 62.758 105.169 17.551 1.00 33.56 ? 1168 HOH A O 1 HETATM 4498 O O . HOH T 8 . ? 50.697 86.007 42.183 1.00 69.43 ? 1169 HOH A O 1 HETATM 4499 O O . HOH T 8 . ? 55.194 125.831 1.123 1.00 54.76 ? 1170 HOH A O 1 HETATM 4500 O O . HOH T 8 . ? 56.330 126.494 24.773 1.00 48.64 ? 1171 HOH A O 1 HETATM 4501 O O . HOH T 8 . ? 36.092 102.663 10.919 1.00 41.29 ? 1172 HOH A O 1 HETATM 4502 O O . HOH T 8 . ? 48.863 98.136 9.766 1.00 52.62 ? 1173 HOH A O 1 HETATM 4503 O O . HOH T 8 . ? 60.268 96.198 -0.700 1.00 43.52 ? 1174 HOH A O 1 HETATM 4504 O O . HOH T 8 . ? 65.576 132.846 10.994 1.00 57.43 ? 1175 HOH A O 1 HETATM 4505 O O . HOH T 8 . ? 80.428 130.472 37.404 1.00 64.99 ? 1176 HOH A O 1 HETATM 4506 O O . HOH T 8 . ? 41.174 122.333 22.412 1.00 51.86 ? 1177 HOH A O 1 HETATM 4507 O O . HOH T 8 . ? 77.349 98.209 15.768 1.00 46.94 ? 1178 HOH A O 1 HETATM 4508 O O . HOH T 8 . ? 58.668 114.457 9.621 1.00 35.55 ? 1179 HOH A O 1 HETATM 4509 O O . HOH T 8 . ? 52.308 108.621 40.535 1.00 40.61 ? 1180 HOH A O 1 HETATM 4510 O O . HOH T 8 . ? 46.845 113.826 30.972 1.00 36.68 ? 1181 HOH A O 1 HETATM 4511 O O . HOH T 8 . ? 74.831 120.647 33.002 1.00 42.99 ? 1182 HOH A O 1 HETATM 4512 O O . HOH T 8 . ? 77.873 102.729 29.947 1.00 51.10 ? 1183 HOH A O 1 HETATM 4513 O O . HOH T 8 . ? 56.291 117.528 27.469 1.00 46.63 ? 1184 HOH A O 1 HETATM 4514 O O . HOH T 8 . ? 44.516 92.223 41.092 1.00 51.18 ? 1185 HOH A O 1 HETATM 4515 O O . HOH T 8 . ? 72.929 122.170 51.402 1.00 59.96 ? 1186 HOH A O 1 HETATM 4516 O O . HOH T 8 . ? 62.937 100.262 -1.166 1.00 38.78 ? 1187 HOH A O 1 HETATM 4517 O O . HOH T 8 . ? 50.171 115.943 43.665 1.00 41.99 ? 1188 HOH A O 1 HETATM 4518 O O . HOH T 8 . ? 57.128 104.266 3.765 1.00 45.55 ? 1189 HOH A O 1 HETATM 4519 O O . HOH T 8 . ? 61.081 126.679 -6.140 1.00 63.34 ? 1190 HOH A O 1 HETATM 4520 O O . HOH T 8 . ? 80.072 112.309 36.739 1.00 54.36 ? 1191 HOH A O 1 HETATM 4521 O O . HOH T 8 . ? 70.352 135.372 29.085 1.00 59.54 ? 1192 HOH A O 1 HETATM 4522 O O . HOH T 8 . ? 45.072 110.328 40.837 1.00 42.13 ? 1193 HOH A O 1 HETATM 4523 O O . HOH T 8 . ? 62.224 118.189 40.393 1.00 34.14 ? 1194 HOH A O 1 HETATM 4524 O O . HOH T 8 . ? 59.365 121.200 45.808 1.00 43.72 ? 1195 HOH A O 1 HETATM 4525 O O . HOH T 8 . ? 43.374 121.678 27.140 1.00 43.49 ? 1196 HOH A O 1 HETATM 4526 O O . HOH T 8 . ? 45.004 113.186 26.842 1.00 46.04 ? 1197 HOH A O 1 HETATM 4527 O O . HOH T 8 . ? 44.010 112.766 24.501 1.00 51.01 ? 1198 HOH A O 1 HETATM 4528 O O . HOH T 8 . ? 61.289 122.103 47.300 1.00 47.73 ? 1199 HOH A O 1 HETATM 4529 O O . HOH T 8 . ? 42.125 90.500 42.166 1.00 67.83 ? 1200 HOH A O 1 HETATM 4530 O O . HOH T 8 . ? 54.663 85.534 30.023 1.00 54.44 ? 1201 HOH A O 1 HETATM 4531 O O . HOH T 8 . ? 56.893 84.835 28.995 1.00 44.58 ? 1202 HOH A O 1 HETATM 4532 O O . HOH T 8 . ? 85.727 104.790 28.548 1.00 50.77 ? 1203 HOH A O 1 HETATM 4533 O O . HOH T 8 . ? 60.560 90.697 42.621 1.00 41.44 ? 1204 HOH A O 1 HETATM 4534 O O . HOH T 8 . ? 74.331 91.016 26.865 1.00 49.66 ? 1205 HOH A O 1 HETATM 4535 O O . HOH T 8 . ? 78.266 113.844 22.671 1.00 72.99 ? 1206 HOH A O 1 HETATM 4536 O O . HOH T 8 . ? 77.499 104.576 16.528 1.00 45.89 ? 1207 HOH A O 1 HETATM 4537 O O . HOH T 8 . ? 84.084 95.373 19.535 1.00 43.92 ? 1208 HOH A O 1 HETATM 4538 O O . HOH T 8 . ? 78.279 123.752 10.490 1.00 54.25 ? 1209 HOH A O 1 HETATM 4539 O O . HOH T 8 . ? 61.512 112.736 3.922 1.00 46.44 ? 1210 HOH A O 1 HETATM 4540 O O . HOH T 8 . ? 80.007 91.216 14.399 1.00 63.11 ? 1211 HOH A O 1 HETATM 4541 O O . HOH T 8 . ? 45.668 108.290 8.629 1.00 46.98 ? 1212 HOH A O 1 HETATM 4542 O O . HOH T 8 . ? 33.485 104.398 13.170 1.00 52.09 ? 1213 HOH A O 1 HETATM 4543 O O . HOH T 8 . ? 40.516 90.209 22.022 1.00 62.84 ? 1214 HOH A O 1 HETATM 4544 O O . HOH T 8 . ? 61.895 87.268 9.839 1.00 38.69 ? 1215 HOH A O 1 HETATM 4545 O O . HOH T 8 . ? 60.253 92.858 1.771 1.00 40.63 ? 1216 HOH A O 1 HETATM 4546 O O . HOH T 8 . ? 45.705 104.578 8.521 1.00 48.13 ? 1217 HOH A O 1 HETATM 4547 O O . HOH T 8 . ? 76.625 109.438 11.624 1.00 66.64 ? 1218 HOH A O 1 HETATM 4548 O O . HOH T 8 . ? 36.566 102.737 38.177 1.00 56.72 ? 1219 HOH A O 1 HETATM 4549 O O . HOH T 8 . ? 75.420 111.782 43.420 1.00 59.13 ? 1220 HOH A O 1 HETATM 4550 O O . HOH T 8 . ? 83.624 112.954 26.678 1.00 58.42 ? 1221 HOH A O 1 HETATM 4551 O O . HOH T 8 . ? 61.803 114.375 1.758 1.00 47.91 ? 1222 HOH A O 1 HETATM 4552 O O . HOH T 8 . ? 59.565 111.050 3.437 1.00 42.32 ? 1223 HOH A O 1 HETATM 4553 O O . HOH T 8 . ? 62.631 87.217 18.429 1.00 37.78 ? 1224 HOH A O 1 HETATM 4554 O O . HOH T 8 . ? 68.278 121.860 47.703 1.00 55.27 ? 1225 HOH A O 1 HETATM 4555 O O . HOH T 8 . ? 45.700 129.669 22.786 1.00 39.91 ? 1226 HOH A O 1 HETATM 4556 O O . HOH T 8 . ? 52.637 109.522 38.504 1.00 45.62 ? 1227 HOH A O 1 HETATM 4557 O O . HOH T 8 . ? 79.885 93.564 13.720 1.00 57.43 ? 1228 HOH A O 1 HETATM 4558 O O . HOH T 8 . ? 69.339 116.792 -5.081 1.00 55.40 ? 1229 HOH A O 1 HETATM 4559 O O . HOH T 8 . ? 54.250 98.614 56.385 1.00 66.22 ? 1230 HOH A O 1 HETATM 4560 O O . HOH T 8 . ? 58.513 109.618 49.577 1.00 51.18 ? 1231 HOH A O 1 HETATM 4561 O O . HOH T 8 . ? 66.589 115.536 52.093 1.00 48.75 ? 1232 HOH A O 1 HETATM 4562 O O . HOH T 8 . ? 64.474 125.073 48.102 1.00 59.11 ? 1233 HOH A O 1 HETATM 4563 O O . HOH T 8 . ? 45.589 108.486 51.941 1.00 57.74 ? 1234 HOH A O 1 HETATM 4564 O O . HOH T 8 . ? 44.340 114.476 32.806 1.00 60.52 ? 1235 HOH A O 1 HETATM 4565 O O . HOH T 8 . ? 56.834 116.804 50.177 1.00 54.82 ? 1236 HOH A O 1 HETATM 4566 O O . HOH T 8 . ? 52.434 87.759 31.206 1.00 51.68 ? 1237 HOH A O 1 HETATM 4567 O O . HOH T 8 . ? 73.918 120.846 30.524 1.00 49.67 ? 1238 HOH A O 1 HETATM 4568 O O . HOH T 8 . ? 43.177 114.159 28.773 1.00 51.29 ? 1239 HOH A O 1 HETATM 4569 O O . HOH T 8 . ? 78.417 113.970 33.962 1.00 44.15 ? 1240 HOH A O 1 HETATM 4570 O O . HOH T 8 . ? 70.440 102.210 40.588 1.00 56.26 ? 1241 HOH A O 1 HETATM 4571 O O . HOH T 8 . ? 64.601 89.602 41.560 1.00 54.53 ? 1242 HOH A O 1 HETATM 4572 O O . HOH T 8 . ? 73.250 95.025 35.808 1.00 54.18 ? 1243 HOH A O 1 HETATM 4573 O O . HOH T 8 . ? 73.799 107.135 14.504 1.00 53.79 ? 1244 HOH A O 1 HETATM 4574 O O . HOH T 8 . ? 52.475 83.545 28.356 1.00 53.50 ? 1245 HOH A O 1 HETATM 4575 O O . HOH T 8 . ? 75.882 108.572 18.559 1.00 67.29 ? 1246 HOH A O 1 HETATM 4576 O O . HOH T 8 . ? 82.227 97.584 27.262 1.00 61.50 ? 1247 HOH A O 1 HETATM 4577 O O . HOH T 8 . ? 56.547 115.254 7.984 1.00 34.07 ? 1248 HOH A O 1 HETATM 4578 O O . HOH T 8 . ? 50.432 128.506 15.832 1.00 42.70 ? 1249 HOH A O 1 HETATM 4579 O O . HOH T 8 . ? 45.524 121.677 7.732 1.00 48.94 ? 1250 HOH A O 1 HETATM 4580 O O . HOH T 8 . ? 60.816 133.365 -1.366 1.00 49.16 ? 1251 HOH A O 1 HETATM 4581 O O . HOH T 8 . ? 56.385 117.402 6.646 1.00 49.84 ? 1252 HOH A O 1 HETATM 4582 O O . HOH T 8 . ? 40.071 105.946 25.917 1.00 51.95 ? 1253 HOH A O 1 HETATM 4583 O O . HOH T 8 . ? 51.574 86.250 11.711 1.00 55.10 ? 1254 HOH A O 1 HETATM 4584 O O . HOH T 8 . ? 65.926 90.621 5.699 1.00 38.47 ? 1255 HOH A O 1 HETATM 4585 O O . HOH T 8 . ? 65.680 95.127 0.652 1.00 42.20 ? 1256 HOH A O 1 HETATM 4586 O O . HOH T 8 . ? 62.386 88.273 5.686 1.00 51.10 ? 1257 HOH A O 1 HETATM 4587 O O . HOH T 8 . ? 64.169 111.485 -1.172 1.00 69.61 ? 1258 HOH A O 1 HETATM 4588 O O . HOH T 8 . ? 74.933 114.877 12.722 1.00 53.69 ? 1259 HOH A O 1 HETATM 4589 O O . HOH T 8 . ? 35.874 100.017 30.539 1.00 54.22 ? 1260 HOH A O 1 HETATM 4590 O O . HOH T 8 . ? 48.728 126.005 28.304 1.00 59.60 ? 1261 HOH A O 1 HETATM 4591 O O . HOH T 8 . ? 58.906 90.717 45.695 1.00 56.32 ? 1262 HOH A O 1 HETATM 4592 O O . HOH T 8 . ? 81.544 114.495 25.591 1.00 61.63 ? 1263 HOH A O 1 HETATM 4593 O O . HOH T 8 . ? 64.838 92.623 0.359 1.00 50.46 ? 1264 HOH A O 1 HETATM 4594 O O . HOH T 8 . ? 67.735 102.440 -1.425 1.00 51.83 ? 1265 HOH A O 1 HETATM 4595 O O . HOH T 8 . ? 54.351 116.677 48.585 1.00 73.01 ? 1266 HOH A O 1 HETATM 4596 O O . HOH T 8 . ? 43.371 112.051 33.303 1.00 57.73 ? 1267 HOH A O 1 HETATM 4597 O O . HOH T 8 . ? 53.723 121.018 45.422 1.00 62.26 ? 1268 HOH A O 1 HETATM 4598 O O . HOH T 8 . ? 77.734 110.854 21.966 1.00 71.33 ? 1269 HOH A O 1 HETATM 4599 O O . HOH T 8 . ? 77.566 103.741 13.986 1.00 65.15 ? 1270 HOH A O 1 HETATM 4600 O O . HOH T 8 . ? 68.748 119.164 54.050 1.00 56.04 ? 1271 HOH A O 1 HETATM 4601 O O . HOH T 8 . ? 65.892 122.488 26.763 1.00 52.90 ? 1272 HOH A O 1 HETATM 4602 O O . HOH T 8 . ? 68.567 119.903 19.993 1.00 48.51 ? 1273 HOH A O 1 HETATM 4603 O O . HOH T 8 . ? 65.627 131.880 44.905 1.00 56.70 ? 1274 HOH A O 1 HETATM 4604 O O . HOH T 8 . ? 55.791 115.116 3.662 1.00 50.86 ? 1275 HOH A O 1 HETATM 4605 O O . HOH T 8 . ? 42.647 113.631 12.247 1.00 55.55 ? 1276 HOH A O 1 HETATM 4606 O O . HOH T 8 . ? 42.210 98.871 11.245 1.00 57.26 ? 1277 HOH A O 1 HETATM 4607 O O . HOH T 8 . ? 48.624 94.034 11.502 1.00 52.62 ? 1278 HOH A O 1 HETATM 4608 O O . HOH T 8 . ? 67.068 97.530 -2.333 1.00 61.25 ? 1279 HOH A O 1 HETATM 4609 O O . HOH T 8 . ? 77.886 90.690 24.704 1.00 60.88 ? 1280 HOH A O 1 HETATM 4610 O O . HOH T 8 . ? 61.351 88.142 43.600 1.00 61.79 ? 1281 HOH A O 1 HETATM 4611 O O . HOH T 8 . ? 87.324 122.488 48.316 1.00 61.98 ? 1282 HOH A O 1 HETATM 4612 O O . HOH T 8 . ? 75.087 128.488 17.986 1.00 71.09 ? 1283 HOH A O 1 HETATM 4613 O O . HOH T 8 . ? 80.220 115.135 30.513 1.00 73.59 ? 1284 HOH A O 1 HETATM 4614 O O . HOH T 8 . ? 46.018 133.029 8.512 1.00 49.19 ? 1285 HOH A O 1 HETATM 4615 O O . HOH T 8 . ? 64.619 116.930 -3.007 1.00 61.76 ? 1286 HOH A O 1 HETATM 4616 O O . HOH T 8 . ? 76.295 106.478 44.464 1.00 64.23 ? 1287 HOH A O 1 HETATM 4617 O O . HOH T 8 . ? 86.710 108.087 28.233 1.00 64.04 ? 1288 HOH A O 1 HETATM 4618 O O . HOH T 8 . ? 72.918 109.065 13.446 0.50 44.02 ? 1289 HOH A O 1 HETATM 4619 O O . HOH T 8 . ? 76.033 125.114 25.283 1.00 61.29 ? 1290 HOH A O 1 HETATM 4620 O O . HOH T 8 . ? 85.079 122.598 49.503 1.00 63.80 ? 1291 HOH A O 1 HETATM 4621 O O . HOH T 8 . ? 60.080 127.605 44.187 1.00 65.88 ? 1292 HOH A O 1 HETATM 4622 O O . HOH T 8 . ? 66.030 113.377 -0.087 1.00 70.21 ? 1293 HOH A O 1 HETATM 4623 O O . HOH T 8 . ? 72.018 90.737 7.171 1.00 60.69 ? 1294 HOH A O 1 HETATM 4624 O O . HOH T 8 . ? 64.255 107.127 -0.145 1.00 59.20 ? 1295 HOH A O 1 HETATM 4625 O O . HOH T 8 . ? 76.649 117.811 0.034 0.50 47.39 ? 1296 HOH A O 1 HETATM 4626 O O . HOH T 8 . ? 49.838 109.352 45.796 1.00 65.27 ? 1297 HOH A O 1 HETATM 4627 O O . HOH T 8 . ? 52.446 111.630 48.026 1.00 62.48 ? 1298 HOH A O 1 HETATM 4628 O O . HOH T 8 . ? 40.919 115.388 20.893 1.00 58.16 ? 1299 HOH A O 1 HETATM 4629 O O . HOH T 8 . ? 39.078 106.062 31.696 1.00 61.10 ? 1300 HOH A O 1 HETATM 4630 O O . HOH T 8 . ? 64.159 89.557 7.550 1.00 42.85 ? 1301 HOH A O 1 HETATM 4631 O O . HOH T 8 . ? 44.438 123.508 15.875 1.00 61.36 ? 1302 HOH A O 1 HETATM 4632 O O . HOH T 8 . ? 63.052 120.853 35.155 1.00 59.22 ? 1303 HOH A O 1 HETATM 4633 O O . HOH T 8 . ? 69.804 104.665 40.951 1.00 45.76 ? 1304 HOH A O 1 HETATM 4634 O O . HOH T 8 . ? 78.811 114.186 27.580 1.00 44.55 ? 1305 HOH A O 1 HETATM 4635 O O . HOH T 8 . ? 66.574 128.752 17.178 1.00 51.99 ? 1306 HOH A O 1 HETATM 4636 O O . HOH T 8 . ? 56.291 129.254 14.500 1.00 48.68 ? 1307 HOH A O 1 HETATM 4637 O O . HOH T 8 . ? 69.522 129.120 5.827 1.00 59.60 ? 1308 HOH A O 1 HETATM 4638 O O . HOH T 8 . ? 58.380 111.543 10.457 1.00 89.78 ? 1309 HOH A O 1 HETATM 4639 O O . HOH T 8 . ? 72.984 113.806 11.209 1.00 43.89 ? 1310 HOH A O 1 HETATM 4640 O O . HOH T 8 . ? 72.020 112.349 14.888 1.00 52.39 ? 1311 HOH A O 1 HETATM 4641 O O . HOH T 8 . ? 77.182 118.538 11.222 1.00 61.08 ? 1312 HOH A O 1 HETATM 4642 O O . HOH T 8 . ? 47.298 112.981 28.249 1.00 43.49 ? 1313 HOH A O 1 HETATM 4643 O O . HOH T 8 . ? 71.460 115.770 26.348 1.00 87.08 ? 1314 HOH A O 1 HETATM 4644 O O . HOH T 8 . ? 66.594 120.287 14.055 1.00 55.54 ? 1315 HOH A O 1 HETATM 4645 O O . HOH T 8 . ? 70.246 121.974 15.447 1.00 54.58 ? 1316 HOH A O 1 HETATM 4646 O O . HOH T 8 . ? 50.995 123.036 42.936 1.00 40.14 ? 1317 HOH A O 1 HETATM 4647 O O . HOH T 8 . ? 71.398 87.354 22.639 1.00 50.26 ? 1318 HOH A O 1 HETATM 4648 O O . HOH T 8 . ? 44.923 127.502 29.888 1.00 53.62 ? 1319 HOH A O 1 HETATM 4649 O O . HOH T 8 . ? 54.302 116.798 31.698 1.00 46.30 ? 1320 HOH A O 1 HETATM 4650 O O . HOH T 8 . ? 59.991 112.918 7.806 1.00 32.23 ? 1321 HOH A O 1 HETATM 4651 O O . HOH T 8 . ? 50.686 112.702 6.530 1.00 52.84 ? 1322 HOH A O 1 HETATM 4652 O O . HOH T 8 . ? 52.983 106.880 4.214 1.00 52.94 ? 1323 HOH A O 1 HETATM 4653 O O . HOH T 8 . ? 60.772 106.843 2.123 1.00 52.70 ? 1324 HOH A O 1 HETATM 4654 O O . HOH T 8 . ? 44.328 124.974 10.360 1.00 62.46 ? 1325 HOH A O 1 HETATM 4655 O O . HOH T 8 . ? 79.810 128.006 4.946 1.00 56.24 ? 1326 HOH A O 1 HETATM 4656 O O . HOH T 8 . ? 46.429 87.270 18.680 1.00 44.71 ? 1327 HOH A O 1 HETATM 4657 O O . HOH T 8 . ? 52.338 94.906 0.289 1.00 58.86 ? 1328 HOH A O 1 HETATM 4658 O O . HOH T 8 . ? 58.019 106.701 3.197 1.00 54.22 ? 1329 HOH A O 1 HETATM 4659 O O . HOH T 8 . ? 52.998 119.515 5.794 1.00 44.38 ? 1330 HOH A O 1 HETATM 4660 O O . HOH T 8 . ? 58.349 97.653 56.575 1.00 61.80 ? 1331 HOH A O 1 HETATM 4661 O O . HOH T 8 . ? 47.461 118.804 45.421 1.00 48.04 ? 1332 HOH A O 1 HETATM 4662 O O . HOH T 8 . ? 77.564 136.037 30.443 1.00 74.82 ? 1333 HOH A O 1 HETATM 4663 O O . HOH T 8 . ? 62.213 92.335 -0.028 0.50 41.35 ? 1334 HOH A O 1 HETATM 4664 O O . HOH T 8 . ? 36.803 104.751 20.495 1.00 57.96 ? 1335 HOH A O 1 HETATM 4665 O O . HOH T 8 . ? 49.266 113.801 44.351 1.00 56.27 ? 1336 HOH A O 1 HETATM 4666 O O . HOH T 8 . ? 43.634 119.213 27.565 1.00 53.46 ? 1337 HOH A O 1 HETATM 4667 O O . HOH T 8 . ? 79.390 134.634 31.066 1.00 68.28 ? 1338 HOH A O 1 HETATM 4668 O O . HOH T 8 . ? 52.773 129.178 16.426 1.00 48.80 ? 1339 HOH A O 1 HETATM 4669 O O . HOH T 8 . ? 58.822 123.219 -8.717 1.00 66.72 ? 1340 HOH A O 1 HETATM 4670 O O . HOH T 8 . ? 51.456 101.127 4.034 1.00 48.83 ? 1341 HOH A O 1 HETATM 4671 O O . HOH T 8 . ? 60.922 84.860 38.044 1.00 56.12 ? 1342 HOH A O 1 HETATM 4672 O O . HOH T 8 . ? 36.651 104.780 9.530 1.00 56.79 ? 1343 HOH A O 1 HETATM 4673 O O . HOH T 8 . ? 80.449 120.162 33.743 1.00 71.91 ? 1344 HOH A O 1 HETATM 4674 O O . HOH T 8 . ? 56.895 125.382 36.462 1.00 42.28 ? 1345 HOH A O 1 HETATM 4675 O O . HOH T 8 . ? 48.176 136.848 12.731 1.00 58.91 ? 1346 HOH A O 1 HETATM 4676 O O . HOH T 8 . ? 83.312 133.680 45.436 1.00 58.63 ? 1347 HOH A O 1 HETATM 4677 O O . HOH T 8 . ? 70.325 105.243 3.954 1.00 50.79 ? 1348 HOH A O 1 HETATM 4678 O O . HOH T 8 . ? 45.101 96.899 12.230 1.00 59.64 ? 1349 HOH A O 1 HETATM 4679 O O . HOH T 8 . ? 77.091 129.429 -0.129 0.50 82.23 ? 1350 HOH A O 1 HETATM 4680 O O . HOH T 8 . ? 55.996 127.679 26.814 1.00 58.12 ? 1351 HOH A O 1 HETATM 4681 O O . HOH T 8 . ? 81.173 118.968 31.380 1.00 61.79 ? 1352 HOH A O 1 HETATM 4682 O O . HOH T 8 . ? 56.246 85.925 32.899 1.00 57.10 ? 1353 HOH A O 1 HETATM 4683 O O . HOH T 8 . ? 39.730 117.948 18.170 1.00 61.55 ? 1354 HOH A O 1 HETATM 4684 O O . HOH T 8 . ? 40.645 120.493 20.388 1.00 65.26 ? 1355 HOH A O 1 HETATM 4685 O O . HOH T 8 . ? 79.655 130.036 7.677 1.00 57.05 ? 1356 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLU 1 1 ? ? ? A . n A 1 2 ASP 2 2 ? ? ? A . n A 1 3 ASP 3 3 ? ? ? A . n A 1 4 ILE 4 4 4 ILE ILE A . n A 1 5 ILE 5 5 5 ILE ILE A . n A 1 6 ILE 6 6 6 ILE ILE A . n A 1 7 ALA 7 7 7 ALA ALA A . n A 1 8 THR 8 8 8 THR THR A . n A 1 9 LYS 9 9 9 LYS LYS A . n A 1 10 ASN 10 10 10 ASN ASN A . n A 1 11 GLY 11 11 11 GLY GLY A . n A 1 12 LYS 12 12 12 LYS LYS A . n A 1 13 VAL 13 13 13 VAL VAL A . n A 1 14 ARG 14 14 14 ARG ARG A . n A 1 15 GLY 15 15 15 GLY GLY A . n A 1 16 MET 16 16 16 MET MET A . n A 1 17 GLN 17 17 17 GLN GLN A . n A 1 18 LEU 18 18 18 LEU LEU A . n A 1 19 THR 19 19 19 THR THR A . n A 1 20 VAL 20 20 20 VAL VAL A . n A 1 21 PHE 21 21 21 PHE PHE A . n A 1 22 GLY 22 22 22 GLY GLY A . n A 1 23 GLY 23 23 23 GLY GLY A . n A 1 24 THR 24 24 24 THR THR A . n A 1 25 VAL 25 25 25 VAL VAL A . n A 1 26 THR 26 26 26 THR THR A . n A 1 27 ALA 27 27 27 ALA ALA A . n A 1 28 PHE 28 28 28 PHE PHE A . n A 1 29 LEU 29 29 29 LEU LEU A . n A 1 30 GLY 30 30 30 GLY GLY A . n A 1 31 ILE 31 31 31 ILE ILE A . n A 1 32 PRO 32 32 32 PRO PRO A . n A 1 33 TYR 33 33 33 TYR TYR A . n A 1 34 ALA 34 34 34 ALA ALA A . n A 1 35 GLN 35 35 35 GLN GLN A . n A 1 36 PRO 36 36 36 PRO PRO A . n A 1 37 PRO 37 37 37 PRO PRO A . n A 1 38 LEU 38 38 38 LEU LEU A . n A 1 39 GLY 39 39 39 GLY GLY A . n A 1 40 ARG 40 40 40 ARG ARG A . n A 1 41 LEU 41 41 41 LEU LEU A . n A 1 42 ARG 42 42 42 ARG ARG A . n A 1 43 PHE 43 43 43 PHE PHE A . n A 1 44 LYS 44 44 44 LYS LYS A . n A 1 45 LYS 45 45 45 LYS LYS A . n A 1 46 PRO 46 46 46 PRO PRO A . n A 1 47 GLN 47 47 47 GLN GLN A . n A 1 48 SER 48 48 48 SER SER A . n A 1 49 LEU 49 49 49 LEU LEU A . n A 1 50 THR 50 50 50 THR THR A . n A 1 51 LYS 51 51 51 LYS LYS A . n A 1 52 TRP 52 52 52 TRP TRP A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 ASP 54 54 54 ASP ASP A . n A 1 55 ILE 55 55 55 ILE ILE A . n A 1 56 TRP 56 56 56 TRP TRP A . n A 1 57 ASN 57 57 57 ASN ASN A . n A 1 58 ALA 58 58 58 ALA ALA A . n A 1 59 THR 59 59 59 THR THR A . n A 1 60 LYS 60 60 60 LYS LYS A . n A 1 61 TYR 61 61 61 TYR TYR A . n A 1 62 ALA 62 62 62 ALA ALA A . n A 1 63 ASN 63 63 63 ASN ASN A . n A 1 64 SER 64 64 64 SER SER A . n A 1 65 CYS 65 65 65 CYS CYS A . n A 1 66 CSS 66 66 66 CSS CSS A . n A 1 67 GLN 67 67 67 GLN GLN A . n A 1 68 ASN 68 68 68 ASN ASN A . n A 1 69 ILE 69 69 69 ILE ILE A . n A 1 70 ASP 70 70 70 ASP ASP A . n A 1 71 GLN 71 71 71 GLN GLN A . n A 1 72 SER 72 72 72 SER SER A . n A 1 73 PHE 73 73 73 PHE PHE A . n A 1 74 PRO 74 74 74 PRO PRO A . n A 1 75 GLY 75 75 75 GLY GLY A . n A 1 76 PHE 76 76 76 PHE PHE A . n A 1 77 HIS 77 77 77 HIS HIS A . n A 1 78 GLY 78 78 78 GLY GLY A . n A 1 79 SER 79 79 79 SER SER A . n A 1 80 GLU 80 80 80 GLU GLU A . n A 1 81 MET 81 81 81 MET MET A . n A 1 82 TRP 82 82 82 TRP TRP A . n A 1 83 ASN 83 83 83 ASN ASN A . n A 1 84 PRO 84 84 84 PRO PRO A . n A 1 85 ASN 85 85 85 ASN ASN A . n A 1 86 THR 86 86 86 THR THR A . n A 1 87 ASP 87 87 87 ASP ASP A . n A 1 88 LEU 88 88 88 LEU LEU A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 GLU 90 90 90 GLU GLU A . n A 1 91 ASP 91 91 91 ASP ASP A . n A 1 92 CYS 92 92 92 CYS CYS A . n A 1 93 LEU 93 93 93 LEU LEU A . n A 1 94 TYR 94 94 94 TYR TYR A . n A 1 95 LEU 95 95 95 LEU LEU A . n A 1 96 ASN 96 96 96 ASN ASN A . n A 1 97 VAL 97 97 97 VAL VAL A . n A 1 98 TRP 98 98 98 TRP TRP A . n A 1 99 ILE 99 99 99 ILE ILE A . n A 1 100 PRO 100 100 100 PRO PRO A . n A 1 101 ALA 101 101 101 ALA ALA A . n A 1 102 PRO 102 102 102 PRO PRO A . n A 1 103 LYS 103 103 103 LYS LYS A . n A 1 104 PRO 104 104 104 PRO PRO A . n A 1 105 LYS 105 105 105 LYS LYS A . n A 1 106 ASN 106 106 106 ASN ASN A . n A 1 107 ALA 107 107 107 ALA ALA A . n A 1 108 THR 108 108 108 THR THR A . n A 1 109 VAL 109 109 109 VAL VAL A . n A 1 110 LEU 110 110 110 LEU LEU A . n A 1 111 ILE 111 111 111 ILE ILE A . n A 1 112 TRP 112 112 112 TRP TRP A . n A 1 113 ILE 113 113 113 ILE ILE A . n A 1 114 TYR 114 114 114 TYR TYR A . n A 1 115 GLY 115 115 115 GLY GLY A . n A 1 116 GLY 116 116 116 GLY GLY A . n A 1 117 GLY 117 117 117 GLY GLY A . n A 1 118 PHE 118 118 118 PHE PHE A . n A 1 119 GLN 119 119 119 GLN GLN A . n A 1 120 THR 120 120 120 THR THR A . n A 1 121 GLY 121 121 121 GLY GLY A . n A 1 122 THR 122 122 122 THR THR A . n A 1 123 SER 123 123 123 SER SER A . n A 1 124 SER 124 124 124 SER SER A . n A 1 125 LEU 125 125 125 LEU LEU A . n A 1 126 HIS 126 126 126 HIS HIS A . n A 1 127 VAL 127 127 127 VAL VAL A . n A 1 128 TYR 128 128 128 TYR TYR A . n A 1 129 ASP 129 129 129 ASP ASP A . n A 1 130 GLY 130 130 130 GLY GLY A . n A 1 131 LYS 131 131 131 LYS LYS A . n A 1 132 PHE 132 132 132 PHE PHE A . n A 1 133 LEU 133 133 133 LEU LEU A . n A 1 134 ALA 134 134 134 ALA ALA A . n A 1 135 ARG 135 135 135 ARG ARG A . n A 1 136 VAL 136 136 136 VAL VAL A . n A 1 137 GLU 137 137 137 GLU GLU A . n A 1 138 ARG 138 138 138 ARG ARG A . n A 1 139 VAL 139 139 139 VAL VAL A . n A 1 140 ILE 140 140 140 ILE ILE A . n A 1 141 VAL 141 141 141 VAL VAL A . n A 1 142 VAL 142 142 142 VAL VAL A . n A 1 143 SER 143 143 143 SER SER A . n A 1 144 MET 144 144 144 MET MET A . n A 1 145 ASN 145 145 145 ASN ASN A . n A 1 146 TYR 146 146 146 TYR TYR A . n A 1 147 ARG 147 147 147 ARG ARG A . n A 1 148 VAL 148 148 148 VAL VAL A . n A 1 149 GLY 149 149 149 GLY GLY A . n A 1 150 ALA 150 150 150 ALA ALA A . n A 1 151 LEU 151 151 151 LEU LEU A . n A 1 152 GLY 152 152 152 GLY GLY A . n A 1 153 PHE 153 153 153 PHE PHE A . n A 1 154 LEU 154 154 154 LEU LEU A . n A 1 155 ALA 155 155 155 ALA ALA A . n A 1 156 LEU 156 156 156 LEU LEU A . n A 1 157 PRO 157 157 157 PRO PRO A . n A 1 158 GLY 158 158 158 GLY GLY A . n A 1 159 ASN 159 159 159 ASN ASN A . n A 1 160 PRO 160 160 160 PRO PRO A . n A 1 161 GLU 161 161 161 GLU GLU A . n A 1 162 ALA 162 162 162 ALA ALA A . n A 1 163 PRO 163 163 163 PRO PRO A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 ASN 165 165 165 ASN ASN A . n A 1 166 MET 166 166 166 MET MET A . n A 1 167 GLY 167 167 167 GLY GLY A . n A 1 168 LEU 168 168 168 LEU LEU A . n A 1 169 PHE 169 169 169 PHE PHE A . n A 1 170 ASP 170 170 170 ASP ASP A . n A 1 171 GLN 171 171 171 GLN GLN A . n A 1 172 GLN 172 172 172 GLN GLN A . n A 1 173 LEU 173 173 173 LEU LEU A . n A 1 174 ALA 174 174 174 ALA ALA A . n A 1 175 LEU 175 175 175 LEU LEU A . n A 1 176 GLN 176 176 176 GLN GLN A . n A 1 177 TRP 177 177 177 TRP TRP A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 GLN 179 179 179 GLN GLN A . n A 1 180 LYS 180 180 180 LYS LYS A . n A 1 181 ASN 181 181 181 ASN ASN A . n A 1 182 ILE 182 182 182 ILE ILE A . n A 1 183 ALA 183 183 183 ALA ALA A . n A 1 184 ALA 184 184 184 ALA ALA A . n A 1 185 PHE 185 185 185 PHE PHE A . n A 1 186 GLY 186 186 186 GLY GLY A . n A 1 187 GLY 187 187 187 GLY GLY A . n A 1 188 ASN 188 188 188 ASN ASN A . n A 1 189 PRO 189 189 189 PRO PRO A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 SER 191 191 191 SER SER A . n A 1 192 VAL 192 192 192 VAL VAL A . n A 1 193 THR 193 193 193 THR THR A . n A 1 194 LEU 194 194 194 LEU LEU A . n A 1 195 PHE 195 195 195 PHE PHE A . n A 1 196 GLY 196 196 196 GLY GLY A . n A 1 197 GLU 197 197 197 GLU GLU A . n A 1 198 SER 198 198 198 SER SER A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 GLY 200 200 200 GLY GLY A . n A 1 201 ALA 201 201 201 ALA ALA A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 SER 203 203 203 SER SER A . n A 1 204 VAL 204 204 204 VAL VAL A . n A 1 205 SER 205 205 205 SER SER A . n A 1 206 LEU 206 206 206 LEU LEU A . n A 1 207 HIS 207 207 207 HIS HIS A . n A 1 208 LEU 208 208 208 LEU LEU A . n A 1 209 LEU 209 209 209 LEU LEU A . n A 1 210 SER 210 210 210 SER SER A . n A 1 211 PRO 211 211 211 PRO PRO A . n A 1 212 GLY 212 212 212 GLY GLY A . n A 1 213 SER 213 213 213 SER SER A . n A 1 214 HIS 214 214 214 HIS HIS A . n A 1 215 SER 215 215 215 SER SER A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 PHE 217 217 217 PHE PHE A . n A 1 218 THR 218 218 218 THR THR A . n A 1 219 ARG 219 219 219 ARG ARG A . n A 1 220 ALA 220 220 220 ALA ALA A . n A 1 221 ILE 221 221 221 ILE ILE A . n A 1 222 LEU 222 222 222 LEU LEU A . n A 1 223 GLN 223 223 223 GLN GLN A . n A 1 224 SER 224 224 224 SER SER A . n A 1 225 GLY 225 225 225 GLY GLY A . n A 1 226 SER 226 226 226 SER SER A . n A 1 227 PHE 227 227 227 PHE PHE A . n A 1 228 ASN 228 228 228 ASN ASN A . n A 1 229 ALA 229 229 229 ALA ALA A . n A 1 230 PRO 230 230 230 PRO PRO A . n A 1 231 TRP 231 231 231 TRP TRP A . n A 1 232 ALA 232 232 232 ALA ALA A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 THR 234 234 234 THR THR A . n A 1 235 SER 235 235 235 SER SER A . n A 1 236 LEU 236 236 236 LEU LEU A . n A 1 237 TYR 237 237 237 TYR TYR A . n A 1 238 GLU 238 238 238 GLU GLU A . n A 1 239 ALA 239 239 239 ALA ALA A . n A 1 240 ARG 240 240 240 ARG ARG A . n A 1 241 ASN 241 241 241 ASN ASN A . n A 1 242 ARG 242 242 242 ARG ARG A . n A 1 243 THR 243 243 243 THR THR A . n A 1 244 LEU 244 244 244 LEU LEU A . n A 1 245 ASN 245 245 245 ASN ASN A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 ALA 247 247 247 ALA ALA A . n A 1 248 LYS 248 248 248 LYS LYS A . n A 1 249 LEU 249 249 249 LEU LEU A . n A 1 250 THR 250 250 250 THR THR A . n A 1 251 GLY 251 251 251 GLY GLY A . n A 1 252 CYS 252 252 252 CYS CYS A . n A 1 253 SER 253 253 253 SER SER A . n A 1 254 ARG 254 254 254 ARG ARG A . n A 1 255 GLU 255 255 255 GLU GLU A . n A 1 256 ASN 256 256 256 ASN ASN A . n A 1 257 GLU 257 257 257 GLU GLU A . n A 1 258 THR 258 258 258 THR THR A . n A 1 259 GLU 259 259 259 GLU GLU A . n A 1 260 ILE 260 260 260 ILE ILE A . n A 1 261 ILE 261 261 261 ILE ILE A . n A 1 262 LYS 262 262 262 LYS LYS A . n A 1 263 CYS 263 263 263 CYS CYS A . n A 1 264 LEU 264 264 264 LEU LEU A . n A 1 265 ARG 265 265 265 ARG ARG A . n A 1 266 ASN 266 266 266 ASN ASN A . n A 1 267 LYS 267 267 267 LYS LYS A . n A 1 268 ASP 268 268 268 ASP ASP A . n A 1 269 PRO 269 269 269 PRO PRO A . n A 1 270 GLN 270 270 270 GLN GLN A . n A 1 271 GLU 271 271 271 GLU GLU A . n A 1 272 ILE 272 272 272 ILE ILE A . n A 1 273 LEU 273 273 273 LEU LEU A . n A 1 274 LEU 274 274 274 LEU LEU A . n A 1 275 ASN 275 275 275 ASN ASN A . n A 1 276 GLU 276 276 276 GLU GLU A . n A 1 277 ALA 277 277 277 ALA ALA A . n A 1 278 PHE 278 278 278 PHE PHE A . n A 1 279 VAL 279 279 279 VAL VAL A . n A 1 280 VAL 280 280 280 VAL VAL A . n A 1 281 PRO 281 281 281 PRO PRO A . n A 1 282 TYR 282 282 282 TYR TYR A . n A 1 283 GLY 283 283 283 GLY GLY A . n A 1 284 THR 284 284 284 THR THR A . n A 1 285 PRO 285 285 285 PRO PRO A . n A 1 286 LEU 286 286 286 LEU LEU A . n A 1 287 SER 287 287 287 SER SER A . n A 1 288 VAL 288 288 288 VAL VAL A . n A 1 289 ASN 289 289 289 ASN ASN A . n A 1 290 PHE 290 290 290 PHE PHE A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 PRO 292 292 292 PRO PRO A . n A 1 293 THR 293 293 293 THR THR A . n A 1 294 VAL 294 294 294 VAL VAL A . n A 1 295 ASP 295 295 295 ASP ASP A . n A 1 296 GLY 296 296 296 GLY GLY A . n A 1 297 ASP 297 297 297 ASP ASP A . n A 1 298 PHE 298 298 298 PHE PHE A . n A 1 299 LEU 299 299 299 LEU LEU A . n A 1 300 THR 300 300 300 THR THR A . n A 1 301 ASP 301 301 301 ASP ASP A . n A 1 302 MET 302 302 302 MET MET A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ASP 304 304 304 ASP ASP A . n A 1 305 ILE 305 305 305 ILE ILE A . n A 1 306 LEU 306 306 306 LEU LEU A . n A 1 307 LEU 307 307 307 LEU LEU A . n A 1 308 GLU 308 308 308 GLU GLU A . n A 1 309 LEU 309 309 309 LEU LEU A . n A 1 310 GLY 310 310 310 GLY GLY A . n A 1 311 GLN 311 311 311 GLN GLN A . n A 1 312 PHE 312 312 312 PHE PHE A . n A 1 313 LYS 313 313 313 LYS LYS A . n A 1 314 LYS 314 314 314 LYS LYS A . n A 1 315 THR 315 315 315 THR THR A . n A 1 316 GLN 316 316 316 GLN GLN A . n A 1 317 ILE 317 317 317 ILE ILE A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 GLY 320 320 320 GLY GLY A . n A 1 321 VAL 321 321 321 VAL VAL A . n A 1 322 ASN 322 322 322 ASN ASN A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 ASP 324 324 324 ASP ASP A . n A 1 325 GLU 325 325 325 GLU GLU A . n A 1 326 GLY 326 326 326 GLY GLY A . n A 1 327 THR 327 327 327 THR THR A . n A 1 328 ALA 328 328 328 ALA ALA A . n A 1 329 PHE 329 329 329 PHE PHE A . n A 1 330 LEU 330 330 330 LEU LEU A . n A 1 331 VAL 331 331 331 VAL VAL A . n A 1 332 TYR 332 332 332 TYR TYR A . n A 1 333 GLY 333 333 333 GLY GLY A . n A 1 334 ALA 334 334 334 ALA ALA A . n A 1 335 PRO 335 335 335 PRO PRO A . n A 1 336 GLY 336 336 336 GLY GLY A . n A 1 337 PHE 337 337 337 PHE PHE A . n A 1 338 SER 338 338 338 SER SER A . n A 1 339 LYS 339 339 339 LYS LYS A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASN 341 341 341 ASN ASN A . n A 1 342 ASN 342 342 342 ASN ASN A . n A 1 343 SER 343 343 343 SER SER A . n A 1 344 ILE 344 344 344 ILE ILE A . n A 1 345 ILE 345 345 345 ILE ILE A . n A 1 346 THR 346 346 346 THR THR A . n A 1 347 ARG 347 347 347 ARG ARG A . n A 1 348 LYS 348 348 348 LYS LYS A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 PHE 350 350 350 PHE PHE A . n A 1 351 GLN 351 351 351 GLN GLN A . n A 1 352 GLU 352 352 352 GLU GLU A . n A 1 353 GLY 353 353 353 GLY GLY A . n A 1 354 LEU 354 354 354 LEU LEU A . n A 1 355 LYS 355 355 355 LYS LYS A . n A 1 356 ILE 356 356 356 ILE ILE A . n A 1 357 PHE 357 357 357 PHE PHE A . n A 1 358 PHE 358 358 358 PHE PHE A . n A 1 359 PRO 359 359 359 PRO PRO A . n A 1 360 GLY 360 360 360 GLY GLY A . n A 1 361 VAL 361 361 361 VAL VAL A . n A 1 362 SER 362 362 362 SER SER A . n A 1 363 GLU 363 363 363 GLU GLU A . n A 1 364 PHE 364 364 364 PHE PHE A . n A 1 365 GLY 365 365 365 GLY GLY A . n A 1 366 LYS 366 366 366 LYS LYS A . n A 1 367 GLU 367 367 367 GLU GLU A . n A 1 368 SER 368 368 368 SER SER A . n A 1 369 ILE 369 369 369 ILE ILE A . n A 1 370 LEU 370 370 370 LEU LEU A . n A 1 371 PHE 371 371 371 PHE PHE A . n A 1 372 HIS 372 372 372 HIS HIS A . n A 1 373 TYR 373 373 373 TYR TYR A . n A 1 374 THR 374 374 374 THR THR A . n A 1 375 ASP 375 375 375 ASP ASP A . n A 1 376 TRP 376 376 376 TRP TRP A . n A 1 377 VAL 377 377 377 VAL VAL A . n A 1 378 ASP 378 378 ? ? ? A . n A 1 379 ASP 379 379 ? ? ? A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 ARG 381 381 381 ARG ARG A . n A 1 382 PRO 382 382 382 PRO PRO A . n A 1 383 GLU 383 383 383 GLU GLU A . n A 1 384 ASN 384 384 384 ASN ASN A . n A 1 385 TYR 385 385 385 TYR TYR A . n A 1 386 ARG 386 386 386 ARG ARG A . n A 1 387 GLU 387 387 387 GLU GLU A . n A 1 388 ALA 388 388 388 ALA ALA A . n A 1 389 LEU 389 389 389 LEU LEU A . n A 1 390 GLY 390 390 390 GLY GLY A . n A 1 391 ASP 391 391 391 ASP ASP A . n A 1 392 VAL 392 392 392 VAL VAL A . n A 1 393 VAL 393 393 393 VAL VAL A . n A 1 394 GLY 394 394 394 GLY GLY A . n A 1 395 ASP 395 395 395 ASP ASP A . n A 1 396 TYR 396 396 396 TYR TYR A . n A 1 397 ASN 397 397 397 ASN ASN A . n A 1 398 PHE 398 398 398 PHE PHE A . n A 1 399 ILE 399 399 399 ILE ILE A . n A 1 400 CYS 400 400 400 CYS CYS A . n A 1 401 PRO 401 401 401 PRO PRO A . n A 1 402 ALA 402 402 402 ALA ALA A . n A 1 403 LEU 403 403 403 LEU LEU A . n A 1 404 GLU 404 404 404 GLU GLU A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 LYS 407 407 407 LYS LYS A . n A 1 408 LYS 408 408 408 LYS LYS A . n A 1 409 PHE 409 409 409 PHE PHE A . n A 1 410 SER 410 410 410 SER SER A . n A 1 411 GLU 411 411 411 GLU GLU A . n A 1 412 TRP 412 412 412 TRP TRP A . n A 1 413 GLY 413 413 413 GLY GLY A . n A 1 414 ASN 414 414 414 ASN ASN A . n A 1 415 ASN 415 415 415 ASN ASN A . n A 1 416 ALA 416 416 416 ALA ALA A . n A 1 417 PHE 417 417 417 PHE PHE A . n A 1 418 PHE 418 418 418 PHE PHE A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 TYR 420 420 420 TYR TYR A . n A 1 421 PHE 421 421 421 PHE PHE A . n A 1 422 GLU 422 422 422 GLU GLU A . n A 1 423 HIS 423 423 423 HIS HIS A . n A 1 424 ARG 424 424 424 ARG ARG A . n A 1 425 SER 425 425 425 SER SER A . n A 1 426 SER 426 426 426 SER SER A . n A 1 427 LYS 427 427 427 LYS LYS A . n A 1 428 LEU 428 428 428 LEU LEU A . n A 1 429 PRO 429 429 429 PRO PRO A . n A 1 430 TRP 430 430 430 TRP TRP A . n A 1 431 PRO 431 431 431 PRO PRO A . n A 1 432 GLU 432 432 432 GLU GLU A . n A 1 433 TRP 433 433 433 TRP TRP A . n A 1 434 MET 434 434 434 MET MET A . n A 1 435 GLY 435 435 435 GLY GLY A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 MET 437 437 437 MET MET A . n A 1 438 HIS 438 438 438 HIS HIS A . n A 1 439 GLY 439 439 439 GLY GLY A . n A 1 440 TYR 440 440 440 TYR TYR A . n A 1 441 GLU 441 441 441 GLU GLU A . n A 1 442 ILE 442 442 442 ILE ILE A . n A 1 443 GLU 443 443 443 GLU GLU A . n A 1 444 PHE 444 444 444 PHE PHE A . n A 1 445 VAL 445 445 445 VAL VAL A . n A 1 446 PHE 446 446 446 PHE PHE A . n A 1 447 GLY 447 447 447 GLY GLY A . n A 1 448 LEU 448 448 448 LEU LEU A . n A 1 449 PRO 449 449 449 PRO PRO A . n A 1 450 LEU 450 450 450 LEU LEU A . n A 1 451 GLU 451 451 451 GLU GLU A . n A 1 452 ARG 452 452 452 ARG ARG A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ASP 454 454 454 ASP ASP A . n A 1 455 GLN 455 455 455 GLN GLN A . n A 1 456 TYR 456 456 456 TYR TYR A . n A 1 457 THR 457 457 457 THR THR A . n A 1 458 LYS 458 458 458 LYS LYS A . n A 1 459 ALA 459 459 459 ALA ALA A . n A 1 460 GLU 460 460 460 GLU GLU A . n A 1 461 GLU 461 461 461 GLU GLU A . n A 1 462 ILE 462 462 462 ILE ILE A . n A 1 463 LEU 463 463 463 LEU LEU A . n A 1 464 SER 464 464 464 SER SER A . n A 1 465 ARG 465 465 465 ARG ARG A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 ILE 467 467 467 ILE ILE A . n A 1 468 VAL 468 468 468 VAL VAL A . n A 1 469 LYS 469 469 469 LYS LYS A . n A 1 470 ARG 470 470 470 ARG ARG A . n A 1 471 TRP 471 471 471 TRP TRP A . n A 1 472 ALA 472 472 472 ALA ALA A . n A 1 473 ASN 473 473 473 ASN ASN A . n A 1 474 PHE 474 474 474 PHE PHE A . n A 1 475 ALA 475 475 475 ALA ALA A . n A 1 476 LYS 476 476 476 LYS LYS A . n A 1 477 TYR 477 477 477 TYR TYR A . n A 1 478 GLY 478 478 478 GLY GLY A . n A 1 479 ASN 479 479 479 ASN ASN A . n A 1 480 PRO 480 480 480 PRO PRO A . n A 1 481 GLN 481 481 481 GLN GLN A . n A 1 482 GLU 482 482 482 GLU GLU A . n A 1 483 THR 483 483 483 THR THR A . n A 1 484 GLN 484 484 484 GLN GLN A . n A 1 485 ASN 485 485 485 ASN ASN A . n A 1 486 GLN 486 486 486 GLN GLN A . n A 1 487 SER 487 487 487 SER SER A . n A 1 488 THR 488 488 488 THR THR A . n A 1 489 SER 489 489 489 SER SER A . n A 1 490 TRP 490 490 490 TRP TRP A . n A 1 491 PRO 491 491 491 PRO PRO A . n A 1 492 VAL 492 492 492 VAL VAL A . n A 1 493 PHE 493 493 493 PHE PHE A . n A 1 494 LYS 494 494 494 LYS LYS A . n A 1 495 SER 495 495 495 SER SER A . n A 1 496 THR 496 496 496 THR THR A . n A 1 497 GLU 497 497 497 GLU GLU A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 LYS 499 499 499 LYS LYS A . n A 1 500 TYR 500 500 500 TYR TYR A . n A 1 501 LEU 501 501 501 LEU LEU A . n A 1 502 THR 502 502 502 THR THR A . n A 1 503 LEU 503 503 503 LEU LEU A . n A 1 504 ASN 504 504 504 ASN ASN A . n A 1 505 THR 505 505 505 THR THR A . n A 1 506 GLU 506 506 506 GLU GLU A . n A 1 507 SER 507 507 507 SER SER A . n A 1 508 THR 508 508 508 THR THR A . n A 1 509 ARG 509 509 509 ARG ARG A . n A 1 510 ILE 510 510 510 ILE ILE A . n A 1 511 MET 511 511 511 MET MET A . n A 1 512 THR 512 512 512 THR THR A . n A 1 513 LYS 513 513 513 LYS LYS A . n A 1 514 LEU 514 514 514 LEU LEU A . n A 1 515 ARG 515 515 515 ARG ARG A . n A 1 516 ALA 516 516 516 ALA ALA A . n A 1 517 GLN 517 517 517 GLN GLN A . n A 1 518 GLN 518 518 518 GLN GLN A . n A 1 519 CYS 519 519 519 CYS CYS A . n A 1 520 ARG 520 520 520 ARG ARG A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 TRP 522 522 522 TRP TRP A . n A 1 523 THR 523 523 523 THR THR A . n A 1 524 SER 524 524 524 SER SER A . n A 1 525 PHE 525 525 525 PHE PHE A . n A 1 526 PHE 526 526 526 PHE PHE A . n A 1 527 PRO 527 527 527 PRO PRO A . n A 1 528 LYS 528 528 528 LYS LYS A . n A 1 529 VAL 529 529 529 VAL VAL A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 530 530 NAG NAG A . C 2 NAG 2 531 531 NAG NAG A . D 3 FUL 3 532 532 FUL FUL A . E 2 NAG 1 533 533 NAG NAG A . F 2 NAG 2 534 534 NAG NAG A . G 2 NAG 1 535 535 NAG NAG A . H 2 NAG 1 536 536 NAG NAG A . I 2 NAG 1 537 537 NAG NAG A . J 4 SO4 1 601 601 SO4 SO4 A . K 4 SO4 1 602 602 SO4 SO4 A . L 4 SO4 1 603 603 SO4 SO4 A . M 5 CL 1 701 701 CL CL A . N 5 CL 1 702 702 CL CL A . O 6 ISP 1 1001 1001 ISP ISP A . P 7 GOL 1 604 604 GOL GOL A . Q 7 GOL 1 605 605 GOL GOL A . R 7 GOL 1 606 606 GOL GOL A . S 7 GOL 1 607 607 GOL GOL A . T 8 HOH 1 1102 1102 HOH HOH A . T 8 HOH 2 1103 1103 HOH HOH A . T 8 HOH 3 1104 1104 HOH HOH A . T 8 HOH 4 1105 1105 HOH HOH A . T 8 HOH 5 1106 1106 HOH HOH A . T 8 HOH 6 1107 1107 HOH HOH A . T 8 HOH 7 1108 1108 HOH HOH A . T 8 HOH 8 1109 1109 HOH HOH A . T 8 HOH 9 1110 1110 HOH HOH A . T 8 HOH 10 1111 1111 HOH HOH A . T 8 HOH 11 1112 1112 HOH HOH A . T 8 HOH 12 1113 1113 HOH HOH A . T 8 HOH 13 1114 1114 HOH HOH A . T 8 HOH 14 1115 1115 HOH HOH A . T 8 HOH 15 1116 1116 HOH HOH A . T 8 HOH 16 1117 1117 HOH HOH A . T 8 HOH 17 1118 1118 HOH HOH A . T 8 HOH 18 1119 1119 HOH HOH A . T 8 HOH 19 1120 1120 HOH HOH A . T 8 HOH 20 1121 1121 HOH HOH A . T 8 HOH 21 1122 1122 HOH HOH A . T 8 HOH 22 1123 1123 HOH HOH A . T 8 HOH 23 1124 1124 HOH HOH A . T 8 HOH 24 1125 1125 HOH HOH A . T 8 HOH 25 1126 1126 HOH HOH A . T 8 HOH 26 1127 1127 HOH HOH A . T 8 HOH 27 1128 1128 HOH HOH A . T 8 HOH 28 1129 1129 HOH HOH A . T 8 HOH 29 1130 1130 HOH HOH A . T 8 HOH 30 1131 1131 HOH HOH A . T 8 HOH 31 1132 1132 HOH HOH A . T 8 HOH 32 1133 1133 HOH HOH A . T 8 HOH 33 1134 1134 HOH HOH A . T 8 HOH 34 1135 1135 HOH HOH A . T 8 HOH 35 1136 1136 HOH HOH A . T 8 HOH 36 1137 1137 HOH HOH A . T 8 HOH 37 1138 1138 HOH HOH A . T 8 HOH 38 1139 1139 HOH HOH A . T 8 HOH 39 1140 1140 HOH HOH A . T 8 HOH 40 1141 1141 HOH HOH A . T 8 HOH 41 1142 1142 HOH HOH A . T 8 HOH 42 1143 1143 HOH HOH A . T 8 HOH 43 1144 1144 HOH HOH A . T 8 HOH 44 1145 1145 HOH HOH A . T 8 HOH 45 1146 1146 HOH HOH A . T 8 HOH 46 1147 1147 HOH HOH A . T 8 HOH 47 1148 1148 HOH HOH A . T 8 HOH 48 1149 1149 HOH HOH A . T 8 HOH 49 1150 1150 HOH HOH A . T 8 HOH 50 1151 1151 HOH HOH A . T 8 HOH 51 1152 1152 HOH HOH A . T 8 HOH 52 1153 1153 HOH HOH A . T 8 HOH 53 1154 1154 HOH HOH A . T 8 HOH 54 1155 1155 HOH HOH A . T 8 HOH 55 1156 1156 HOH HOH A . T 8 HOH 56 1157 1157 HOH HOH A . T 8 HOH 57 1158 1158 HOH HOH A . T 8 HOH 58 1159 1159 HOH HOH A . T 8 HOH 59 1160 1160 HOH HOH A . T 8 HOH 60 1161 1161 HOH HOH A . T 8 HOH 61 1162 1162 HOH HOH A . T 8 HOH 62 1163 1163 HOH HOH A . T 8 HOH 63 1164 1164 HOH HOH A . T 8 HOH 64 1165 1165 HOH HOH A . T 8 HOH 65 1166 1166 HOH HOH A . T 8 HOH 66 1167 1167 HOH HOH A . T 8 HOH 67 1168 1168 HOH HOH A . T 8 HOH 68 1169 1169 HOH HOH A . T 8 HOH 69 1170 1170 HOH HOH A . T 8 HOH 70 1171 1171 HOH HOH A . T 8 HOH 71 1172 1172 HOH HOH A . T 8 HOH 72 1173 1173 HOH HOH A . T 8 HOH 73 1174 1174 HOH HOH A . T 8 HOH 74 1175 1175 HOH HOH A . T 8 HOH 75 1176 1176 HOH HOH A . T 8 HOH 76 1177 1177 HOH HOH A . T 8 HOH 77 1178 1178 HOH HOH A . T 8 HOH 78 1179 1179 HOH HOH A . T 8 HOH 79 1180 1180 HOH HOH A . T 8 HOH 80 1181 1181 HOH HOH A . T 8 HOH 81 1182 1182 HOH HOH A . T 8 HOH 82 1183 1183 HOH HOH A . T 8 HOH 83 1184 1184 HOH HOH A . T 8 HOH 84 1185 1185 HOH HOH A . T 8 HOH 85 1186 1186 HOH HOH A . T 8 HOH 86 1187 1187 HOH HOH A . T 8 HOH 87 1188 1188 HOH HOH A . T 8 HOH 88 1189 1189 HOH HOH A . T 8 HOH 89 1190 1190 HOH HOH A . T 8 HOH 90 1191 1191 HOH HOH A . T 8 HOH 91 1192 1192 HOH HOH A . T 8 HOH 92 1193 1193 HOH HOH A . T 8 HOH 93 1194 1194 HOH HOH A . T 8 HOH 94 1195 1195 HOH HOH A . T 8 HOH 95 1196 1196 HOH HOH A . T 8 HOH 96 1197 1197 HOH HOH A . T 8 HOH 97 1198 1198 HOH HOH A . T 8 HOH 98 1199 1199 HOH HOH A . T 8 HOH 99 1200 1200 HOH HOH A . T 8 HOH 100 1201 1201 HOH HOH A . T 8 HOH 101 1202 1202 HOH HOH A . T 8 HOH 102 1203 1203 HOH HOH A . T 8 HOH 103 1204 1204 HOH HOH A . T 8 HOH 104 1205 1205 HOH HOH A . T 8 HOH 105 1206 1206 HOH HOH A . T 8 HOH 106 1207 1207 HOH HOH A . T 8 HOH 107 1208 1208 HOH HOH A . T 8 HOH 108 1209 1209 HOH HOH A . T 8 HOH 109 1210 1210 HOH HOH A . T 8 HOH 110 1211 1211 HOH HOH A . T 8 HOH 111 1212 1212 HOH HOH A . T 8 HOH 112 1213 1213 HOH HOH A . T 8 HOH 113 1214 1214 HOH HOH A . T 8 HOH 114 1215 1215 HOH HOH A . T 8 HOH 115 1216 1216 HOH HOH A . T 8 HOH 116 1217 1217 HOH HOH A . T 8 HOH 117 1218 1218 HOH HOH A . T 8 HOH 118 1219 1219 HOH HOH A . T 8 HOH 119 1220 1220 HOH HOH A . T 8 HOH 120 1221 1221 HOH HOH A . T 8 HOH 121 1222 1222 HOH HOH A . T 8 HOH 122 1223 1223 HOH HOH A . T 8 HOH 123 1224 1224 HOH HOH A . T 8 HOH 124 1225 1225 HOH HOH A . T 8 HOH 125 1226 1226 HOH HOH A . T 8 HOH 126 1227 1227 HOH HOH A . T 8 HOH 127 1228 1228 HOH HOH A . T 8 HOH 128 1229 1229 HOH HOH A . T 8 HOH 129 1230 1230 HOH HOH A . T 8 HOH 130 1231 1231 HOH HOH A . T 8 HOH 131 1232 1232 HOH HOH A . T 8 HOH 132 1233 1233 HOH HOH A . T 8 HOH 133 1234 1234 HOH HOH A . T 8 HOH 134 1235 1235 HOH HOH A . T 8 HOH 135 1236 1236 HOH HOH A . T 8 HOH 136 1237 1237 HOH HOH A . T 8 HOH 137 1238 1238 HOH HOH A . T 8 HOH 138 1239 1239 HOH HOH A . T 8 HOH 139 1240 1240 HOH HOH A . T 8 HOH 140 1241 1241 HOH HOH A . T 8 HOH 141 1242 1242 HOH HOH A . T 8 HOH 142 1243 1243 HOH HOH A . T 8 HOH 143 1244 1244 HOH HOH A . T 8 HOH 144 1245 1245 HOH HOH A . T 8 HOH 145 1246 1246 HOH HOH A . T 8 HOH 146 1247 1247 HOH HOH A . T 8 HOH 147 1248 1248 HOH HOH A . T 8 HOH 148 1249 1249 HOH HOH A . T 8 HOH 149 1250 1250 HOH HOH A . T 8 HOH 150 1251 1251 HOH HOH A . T 8 HOH 151 1252 1252 HOH HOH A . T 8 HOH 152 1253 1253 HOH HOH A . T 8 HOH 153 1254 1254 HOH HOH A . T 8 HOH 154 1255 1255 HOH HOH A . T 8 HOH 155 1256 1256 HOH HOH A . T 8 HOH 156 1257 1257 HOH HOH A . T 8 HOH 157 1258 1258 HOH HOH A . T 8 HOH 158 1259 1259 HOH HOH A . T 8 HOH 159 1260 1260 HOH HOH A . T 8 HOH 160 1261 1261 HOH HOH A . T 8 HOH 161 1262 1262 HOH HOH A . T 8 HOH 162 1263 1263 HOH HOH A . T 8 HOH 163 1264 1264 HOH HOH A . T 8 HOH 164 1265 1265 HOH HOH A . T 8 HOH 165 1266 1266 HOH HOH A . T 8 HOH 166 1267 1267 HOH HOH A . T 8 HOH 167 1268 1268 HOH HOH A . T 8 HOH 168 1269 1269 HOH HOH A . T 8 HOH 169 1270 1270 HOH HOH A . T 8 HOH 170 1271 1271 HOH HOH A . T 8 HOH 171 1272 1272 HOH HOH A . T 8 HOH 172 1273 1273 HOH HOH A . T 8 HOH 173 1274 1274 HOH HOH A . T 8 HOH 174 1275 1275 HOH HOH A . T 8 HOH 175 1276 1276 HOH HOH A . T 8 HOH 176 1277 1277 HOH HOH A . T 8 HOH 177 1278 1278 HOH HOH A . T 8 HOH 178 1279 1279 HOH HOH A . T 8 HOH 179 1280 1280 HOH HOH A . T 8 HOH 180 1281 1281 HOH HOH A . T 8 HOH 181 1282 1282 HOH HOH A . T 8 HOH 182 1283 1283 HOH HOH A . T 8 HOH 183 1284 1284 HOH HOH A . T 8 HOH 184 1285 1285 HOH HOH A . T 8 HOH 185 1286 1286 HOH HOH A . T 8 HOH 186 1287 1287 HOH HOH A . T 8 HOH 187 1288 1288 HOH HOH A . T 8 HOH 188 1289 1289 HOH HOH A . T 8 HOH 189 1290 1290 HOH HOH A . T 8 HOH 190 1291 1291 HOH HOH A . T 8 HOH 191 1292 1292 HOH HOH A . T 8 HOH 192 1293 1293 HOH HOH A . T 8 HOH 193 1294 1294 HOH HOH A . T 8 HOH 194 1295 1295 HOH HOH A . T 8 HOH 195 1296 1296 HOH HOH A . T 8 HOH 196 1297 1297 HOH HOH A . T 8 HOH 197 1298 1298 HOH HOH A . T 8 HOH 198 1299 1299 HOH HOH A . T 8 HOH 199 1300 1300 HOH HOH A . T 8 HOH 200 1301 1301 HOH HOH A . T 8 HOH 201 1302 1302 HOH HOH A . T 8 HOH 202 1303 1303 HOH HOH A . T 8 HOH 203 1304 1304 HOH HOH A . T 8 HOH 204 1305 1305 HOH HOH A . T 8 HOH 205 1306 1306 HOH HOH A . T 8 HOH 206 1307 1307 HOH HOH A . T 8 HOH 207 1308 1308 HOH HOH A . T 8 HOH 208 1309 1309 HOH HOH A . T 8 HOH 209 1310 1310 HOH HOH A . T 8 HOH 210 1311 1311 HOH HOH A . T 8 HOH 211 1312 1312 HOH HOH A . T 8 HOH 212 1313 1313 HOH HOH A . T 8 HOH 213 1314 1314 HOH HOH A . T 8 HOH 214 1315 1315 HOH HOH A . T 8 HOH 215 1316 1316 HOH HOH A . T 8 HOH 216 1317 1317 HOH HOH A . T 8 HOH 217 1318 1318 HOH HOH A . T 8 HOH 218 1319 1319 HOH HOH A . T 8 HOH 219 1320 1320 HOH HOH A . T 8 HOH 220 1321 1321 HOH HOH A . T 8 HOH 221 1322 1322 HOH HOH A . T 8 HOH 222 1323 1323 HOH HOH A . T 8 HOH 223 1324 1324 HOH HOH A . T 8 HOH 224 1325 1325 HOH HOH A . T 8 HOH 225 1326 1326 HOH HOH A . T 8 HOH 226 1327 1327 HOH HOH A . T 8 HOH 227 1328 1328 HOH HOH A . T 8 HOH 228 1329 1329 HOH HOH A . T 8 HOH 229 1330 1330 HOH HOH A . T 8 HOH 230 1331 1331 HOH HOH A . T 8 HOH 231 1332 1332 HOH HOH A . T 8 HOH 232 1333 1333 HOH HOH A . T 8 HOH 233 1334 1334 HOH HOH A . T 8 HOH 234 1335 1335 HOH HOH A . T 8 HOH 235 1336 1336 HOH HOH A . T 8 HOH 236 1337 1337 HOH HOH A . T 8 HOH 237 1338 1338 HOH HOH A . T 8 HOH 238 1339 1339 HOH HOH A . T 8 HOH 239 1340 1340 HOH HOH A . T 8 HOH 240 1341 1341 HOH HOH A . T 8 HOH 241 1342 1342 HOH HOH A . T 8 HOH 242 1343 1343 HOH HOH A . T 8 HOH 243 1344 1344 HOH HOH A . T 8 HOH 244 1345 1345 HOH HOH A . T 8 HOH 245 1346 1346 HOH HOH A . T 8 HOH 246 1347 1347 HOH HOH A . T 8 HOH 247 1348 1348 HOH HOH A . T 8 HOH 248 1349 1349 HOH HOH A . T 8 HOH 249 1350 1350 HOH HOH A . T 8 HOH 250 1351 1351 HOH HOH A . T 8 HOH 251 1352 1352 HOH HOH A . T 8 HOH 252 1353 1353 HOH HOH A . T 8 HOH 253 1354 1354 HOH HOH A . T 8 HOH 254 1355 1355 HOH HOH A . T 8 HOH 255 1356 1356 HOH HOH A . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 57 A ASN 57 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 106 A ASN 106 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 241 A ASN 241 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 341 A ASN 341 ? ASN 'GLYCOSYLATION SITE' 5 A ASN 485 A ASN 485 ? ASN 'GLYCOSYLATION SITE' 6 A CSS 66 A CSS 66 ? CYS S-MERCAPTOCYSTEINE # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 software_defined_assembly PISA dimeric 2 2 author_defined_assembly ? monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1,2 A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T 2 1 A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 9820 ? 1 MORE -68 ? 1 'SSA (A^2)' 41170 ? # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 5_655 -x+1,y,-z -1.0000000000 0.0000000000 0.0000000000 154.4950000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 # _pdbx_struct_special_symmetry.id 1 _pdbx_struct_special_symmetry.PDB_model_num 1 _pdbx_struct_special_symmetry.auth_asym_id A _pdbx_struct_special_symmetry.auth_comp_id HOH _pdbx_struct_special_symmetry.auth_seq_id 1334 _pdbx_struct_special_symmetry.PDB_ins_code ? _pdbx_struct_special_symmetry.label_asym_id T _pdbx_struct_special_symmetry.label_comp_id HOH _pdbx_struct_special_symmetry.label_seq_id . # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2005-02-01 2 'Structure model' 1 1 2008-04-30 3 'Structure model' 1 2 2011-07-13 4 'Structure model' 1 3 2017-10-11 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' 4 4 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 4 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal HKL-2000 'data reduction' . ? 1 AMoRE phasing . ? 2 REFMAC refinement 5.2 ? 3 HKL-2000 'data scaling' . ? 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OG A SER 198 ? ? P A ISP 1001 ? ? 1.56 2 1 OD1 A ASP 87 ? B O A HOH 1317 ? ? 2.08 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CB A ASP 70 ? ? CG A ASP 70 ? ? OD2 A ASP 70 ? ? 125.69 118.30 7.39 0.90 N 2 1 CB A ASP 87 ? A CG A ASP 87 ? A OD2 A ASP 87 ? A 123.83 118.30 5.53 0.90 N 3 1 CB A ASP 295 ? ? CG A ASP 295 ? ? OD2 A ASP 295 ? ? 123.75 118.30 5.45 0.90 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 54 ? ? 68.60 175.85 2 1 ALA A 58 ? ? -103.43 67.11 3 1 LYS A 103 ? ? -38.05 127.50 4 1 ASN A 106 ? ? -153.42 63.55 5 1 PRO A 157 ? ? -39.91 124.74 6 1 ALA A 162 ? ? -151.10 72.31 7 1 SER A 198 ? ? 51.64 -115.95 8 1 ASP A 297 ? ? -132.82 -77.27 9 1 PHE A 398 ? ? -129.39 -54.55 10 1 GLN A 455 ? ? 84.38 0.62 11 1 GLU A 506 ? ? -65.59 -93.88 # _pdbx_unobs_or_zero_occ_atoms.id 1 _pdbx_unobs_or_zero_occ_atoms.PDB_model_num 1 _pdbx_unobs_or_zero_occ_atoms.polymer_flag N _pdbx_unobs_or_zero_occ_atoms.occupancy_flag 1 _pdbx_unobs_or_zero_occ_atoms.auth_asym_id A _pdbx_unobs_or_zero_occ_atoms.auth_comp_id ISP _pdbx_unobs_or_zero_occ_atoms.auth_seq_id 1001 _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code ? _pdbx_unobs_or_zero_occ_atoms.auth_atom_id O2P _pdbx_unobs_or_zero_occ_atoms.label_alt_id ? _pdbx_unobs_or_zero_occ_atoms.label_asym_id O _pdbx_unobs_or_zero_occ_atoms.label_comp_id ISP _pdbx_unobs_or_zero_occ_atoms.label_seq_id 1 _pdbx_unobs_or_zero_occ_atoms.label_atom_id O2P # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLU 1 ? A GLU 1 2 1 Y 1 A ASP 2 ? A ASP 2 3 1 Y 1 A ASP 3 ? A ASP 3 4 1 Y 1 A ASP 378 ? A ASP 378 5 1 Y 1 A ASP 379 ? A ASP 379 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 BETA-L-FUCOSE FUL 4 'SULFATE ION' SO4 5 'CHLORIDE ION' CL 6 PHOSPHORYLISOPROPANE ISP 7 GLYCEROL GOL 8 water HOH #