data_1T7X # _entry.id 1T7X # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.286 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 1T7X RCSB RCSB022423 WWPDB D_1000022423 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1ZAG . unspecified PDB 1t7v . unspecified PDB 1t7w . unspecified PDB 1t7y . unspecified PDB 1t7z . unspecified PDB 1t80 . unspecified # _pdbx_database_status.entry_id 1T7X _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2004-05-11 _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.SG_entry . _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Delker, S.L.' 1 'West Jr., A.P.' 2 'McDermott, L.' 3 'Kennedy, M.W.' 4 'Bjorkman, P.J.' 5 # loop_ _citation.id _citation.title _citation.journal_abbrev _citation.journal_volume _citation.page_first _citation.page_last _citation.year _citation.journal_id_ASTM _citation.country _citation.journal_id_ISSN _citation.journal_id_CSD _citation.book_publisher _citation.pdbx_database_id_PubMed _citation.pdbx_database_id_DOI primary 'Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein.' J.Struct.Biol. 148 205 213 2004 JSBIEM US 1047-8477 0803 ? 15477100 10.1016/j.jsb.2004.04.009 1 'Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules' Science 283 1914 1919 1999 SCIEAS US 0036-8075 0038 ? ? 10.1126/science.283.5409.1914 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Delker, S.L.' 1 primary 'West Jr., A.P.' 2 primary 'McDermott, L.' 3 primary 'Kennedy, M.W.' 4 primary 'Bjorkman, P.J.' 5 1 'Sanchez, L.M.' 6 1 'Chirino, A.J.' 7 1 'Bjorkman, P.J.' 8 # _cell.entry_id 1T7X _cell.length_a 122.747 _cell.length_b 122.747 _cell.length_c 65.124 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.pdbx_unique_axis ? _cell.Z_PDB 8 # _symmetry.entry_id 1T7X _symmetry.space_group_name_H-M 'P 43 21 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.Int_Tables_number 96 _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Zinc-alpha-2-glycoprotein 32185.953 1 ? 'N89K, N92T' ? ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 3 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Zn-alpha-2-glycoprotein, Zn-alpha-2-GP' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;QENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMET LKDIVEYYKDSTGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKA YLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNG TYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS ; _entity_poly.pdbx_seq_one_letter_code_can ;QENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMET LKDIVEYYKDSTGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKA YLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNG TYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLN n 1 2 GLU n 1 3 ASN n 1 4 GLN n 1 5 ASP n 1 6 GLY n 1 7 ARG n 1 8 TYR n 1 9 SER n 1 10 LEU n 1 11 THR n 1 12 TYR n 1 13 ILE n 1 14 TYR n 1 15 THR n 1 16 GLY n 1 17 LEU n 1 18 SER n 1 19 LYS n 1 20 HIS n 1 21 VAL n 1 22 GLU n 1 23 ASP n 1 24 VAL n 1 25 PRO n 1 26 ALA n 1 27 PHE n 1 28 GLN n 1 29 ALA n 1 30 LEU n 1 31 GLY n 1 32 SER n 1 33 LEU n 1 34 ASN n 1 35 ASP n 1 36 LEU n 1 37 GLN n 1 38 PHE n 1 39 PHE n 1 40 ARG n 1 41 TYR n 1 42 ASN n 1 43 SER n 1 44 LYS n 1 45 ASP n 1 46 ARG n 1 47 LYS n 1 48 SER n 1 49 GLN n 1 50 PRO n 1 51 MET n 1 52 GLY n 1 53 LEU n 1 54 TRP n 1 55 ARG n 1 56 GLN n 1 57 VAL n 1 58 GLU n 1 59 GLY n 1 60 MET n 1 61 GLU n 1 62 ASP n 1 63 TRP n 1 64 LYS n 1 65 GLN n 1 66 ASP n 1 67 SER n 1 68 GLN n 1 69 LEU n 1 70 GLN n 1 71 LYS n 1 72 ALA n 1 73 ARG n 1 74 GLU n 1 75 ASP n 1 76 ILE n 1 77 PHE n 1 78 MET n 1 79 GLU n 1 80 THR n 1 81 LEU n 1 82 LYS n 1 83 ASP n 1 84 ILE n 1 85 VAL n 1 86 GLU n 1 87 TYR n 1 88 TYR n 1 89 LYS n 1 90 ASP n 1 91 SER n 1 92 THR n 1 93 GLY n 1 94 SER n 1 95 HIS n 1 96 VAL n 1 97 LEU n 1 98 GLN n 1 99 GLY n 1 100 ARG n 1 101 PHE n 1 102 GLY n 1 103 CYS n 1 104 GLU n 1 105 ILE n 1 106 GLU n 1 107 ASN n 1 108 ASN n 1 109 ARG n 1 110 SER n 1 111 SER n 1 112 GLY n 1 113 ALA n 1 114 PHE n 1 115 TRP n 1 116 LYS n 1 117 TYR n 1 118 TYR n 1 119 TYR n 1 120 ASP n 1 121 GLY n 1 122 LYS n 1 123 ASP n 1 124 TYR n 1 125 ILE n 1 126 GLU n 1 127 PHE n 1 128 ASN n 1 129 LYS n 1 130 GLU n 1 131 ILE n 1 132 PRO n 1 133 ALA n 1 134 TRP n 1 135 VAL n 1 136 PRO n 1 137 PHE n 1 138 ASP n 1 139 PRO n 1 140 ALA n 1 141 ALA n 1 142 GLN n 1 143 ILE n 1 144 THR n 1 145 LYS n 1 146 GLN n 1 147 LYS n 1 148 TRP n 1 149 GLU n 1 150 ALA n 1 151 GLU n 1 152 PRO n 1 153 VAL n 1 154 TYR n 1 155 VAL n 1 156 GLN n 1 157 ARG n 1 158 ALA n 1 159 LYS n 1 160 ALA n 1 161 TYR n 1 162 LEU n 1 163 GLU n 1 164 GLU n 1 165 GLU n 1 166 CYS n 1 167 PRO n 1 168 ALA n 1 169 THR n 1 170 LEU n 1 171 ARG n 1 172 LYS n 1 173 TYR n 1 174 LEU n 1 175 LYS n 1 176 TYR n 1 177 SER n 1 178 LYS n 1 179 ASN n 1 180 ILE n 1 181 LEU n 1 182 ASP n 1 183 ARG n 1 184 GLN n 1 185 ASP n 1 186 PRO n 1 187 PRO n 1 188 SER n 1 189 VAL n 1 190 VAL n 1 191 VAL n 1 192 THR n 1 193 SER n 1 194 HIS n 1 195 GLN n 1 196 ALA n 1 197 PRO n 1 198 GLY n 1 199 GLU n 1 200 LYS n 1 201 LYS n 1 202 LYS n 1 203 LEU n 1 204 LYS n 1 205 CYS n 1 206 LEU n 1 207 ALA n 1 208 TYR n 1 209 ASP n 1 210 PHE n 1 211 TYR n 1 212 PRO n 1 213 GLY n 1 214 LYS n 1 215 ILE n 1 216 ASP n 1 217 VAL n 1 218 HIS n 1 219 TRP n 1 220 THR n 1 221 ARG n 1 222 ALA n 1 223 GLY n 1 224 GLU n 1 225 VAL n 1 226 GLN n 1 227 GLU n 1 228 PRO n 1 229 GLU n 1 230 LEU n 1 231 ARG n 1 232 GLY n 1 233 ASP n 1 234 VAL n 1 235 LEU n 1 236 HIS n 1 237 ASN n 1 238 GLY n 1 239 ASN n 1 240 GLY n 1 241 THR n 1 242 TYR n 1 243 GLN n 1 244 SER n 1 245 TRP n 1 246 VAL n 1 247 VAL n 1 248 VAL n 1 249 ALA n 1 250 VAL n 1 251 PRO n 1 252 PRO n 1 253 GLN n 1 254 ASP n 1 255 THR n 1 256 ALA n 1 257 PRO n 1 258 TYR n 1 259 SER n 1 260 CYS n 1 261 HIS n 1 262 VAL n 1 263 GLN n 1 264 HIS n 1 265 SER n 1 266 SER n 1 267 LEU n 1 268 ALA n 1 269 GLN n 1 270 PRO n 1 271 LEU n 1 272 VAL n 1 273 VAL n 1 274 PRO n 1 275 TRP n 1 276 GLU n 1 277 ALA n 1 278 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus Homo _entity_src_gen.pdbx_gene_src_gene 'AZGP1, ZAG, ZNGP1' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'Chinese hamster' _entity_src_gen.pdbx_host_org_scientific_name 'Cricetulus griseus' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 10029 _entity_src_gen.host_org_genus Cricetulus _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type PLASMID _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pBJ5-GS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code ZA2G_HUMAN _struct_ref.pdbx_db_accession P25311 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;QENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMET LKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKA YLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNG TYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS ; _struct_ref.pdbx_align_begin 18 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 1T7X _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 278 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession P25311 _struct_ref_seq.db_align_beg 18 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 295 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 1 _struct_ref_seq.pdbx_auth_seq_align_end 278 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 1T7X LYS A 89 ? UNP P25311 ASN 106 ENGINEERED 89 1 1 1T7X THR A 92 ? UNP P25311 ASN 109 ENGINEERED 92 2 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 1T7X _exptl.crystals_number 1 _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 67.72 _exptl_crystal.density_Matthews 3.81 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method MICROBATCH _exptl_crystal_grow.pH 7.5 _exptl_crystal_grow.temp 298.0 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_details 'Ammonium sulfate, PEG 400, HEPES, pH 7.5, Microbatch, temperature 298.0K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 210' _diffrn_detector.pdbx_collection_date 2003-09-28 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator 'Double crystal Si(111)' _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0781 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ALS BEAMLINE 8.2.1' _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.0781 _diffrn_source.pdbx_synchrotron_site ALS _diffrn_source.pdbx_synchrotron_beamline 8.2.1 # _reflns.percent_possible_obs 93.700 _reflns.entry_id 1T7X _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.d_resolution_high 3.1 _reflns.d_resolution_low 20.0 _reflns.number_all ? _reflns.number_obs 8738 _reflns.pdbx_Rmerge_I_obs 0.151 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 12.0 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 3.7 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 3.1 _reflns_shell.d_res_low 3.21 _reflns_shell.percent_possible_obs 86.200 _reflns_shell.Rmerge_I_obs 0.435 _reflns_shell.percent_possible_all 98.2 _reflns_shell.meanI_over_sigI_obs 4.0 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_redundancy ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 1T7X _refine.ls_number_reflns_all 9406 _refine.ls_number_reflns_obs 8832 _refine.ls_percent_reflns_obs 93.9 _refine.ls_d_res_high 3.10 _refine.ls_d_res_low 20.0 _refine.B_iso_min 4.65 _refine.B_iso_max 161.01 _refine.B_iso_mean 36.88 _refine.occupancy_min 1.00 _refine.occupancy_max 1.00 _refine.aniso_B[1][1] 2.73 _refine.aniso_B[2][2] 2.73 _refine.aniso_B[3][3] -5.45 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_param_bsol 13.6085 _refine.solvent_model_param_ksol 0.303916 _refine.solvent_model_details 'CNS bulk solvent model used' _refine.ls_R_factor_R_work 0.232 _refine.ls_R_factor_R_free 0.293 _refine.ls_R_factor_R_free_error 0.014 _refine.ls_number_reflns_R_free 466 _refine.ls_percent_reflns_R_free 5.3 _refine.details ;The difference between the number of observed unique reflections reported for the refinement and the data collection is due to running scalepack a second time over the resolution range used in the refinement to give the merging statistics reported. ; _refine.pdbx_ls_sigma_F ? _refine.pdbx_ls_sigma_I ? _refine.ls_R_factor_all ? _refine.ls_R_factor_obs ? _refine.ls_redundancy_reflns_obs ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model 'PDB Entry 1T7V' _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details Random _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.pdbx_isotropic_thermal_model ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_SU_B ? _refine.overall_SU_ML ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 1T7X _refine_analyze.Luzzati_d_res_low_obs 5.00 _refine_analyze.Luzzati_coordinate_error_obs 0.34 _refine_analyze.Luzzati_sigma_a_obs 0.32 _refine_analyze.Luzzati_coordinate_error_free 0.48 _refine_analyze.Luzzati_sigma_a_free 0.40 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 2232 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 42 _refine_hist.number_atoms_solvent 0 _refine_hist.number_atoms_total 2274 _refine_hist.d_res_high 3.10 _refine_hist.d_res_low 20.0 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function x_bond_d 0.008 . ? ? 'X-RAY DIFFRACTION' ? x_angle_deg 1.3 . ? ? 'X-RAY DIFFRACTION' ? x_torsion_deg 24.4 . ? ? 'X-RAY DIFFRACTION' ? x_torsion_impr_deg 0.77 . ? ? 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.number_reflns_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_work _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.number_reflns_R_free _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.pdbx_refine_id _refine_ls_shell.R_factor_all 3.10 3.21 890 875 832 98.2 0.28 0.297 0.045 43 4.9 . . 'X-RAY DIFFRACTION' . 3.21 3.34 929 908 861 97.6 0.258 0.357 0.052 47 5.2 . . 'X-RAY DIFFRACTION' . 3.34 3.49 919 896 853 97.4 0.235 0.289 0.044 43 4.8 . . 'X-RAY DIFFRACTION' . 3.49 3.67 926 901 852 97.2 0.23 0.326 0.047 49 5.4 . . 'X-RAY DIFFRACTION' . 3.67 3.90 925 893 845 96.4 0.218 0.317 0.046 48 5.4 . . 'X-RAY DIFFRACTION' . 3.90 4.20 932 893 851 95.8 0.192 0.245 0.038 42 4.7 . . 'X-RAY DIFFRACTION' . 4.20 4.62 947 897 845 94.7 0.205 0.279 0.039 52 5.8 . . 'X-RAY DIFFRACTION' . 4.62 5.27 944 787 752 83.3 0.212 0.266 0.045 35 4.4 . . 'X-RAY DIFFRACTION' . 5.27 6.60 975 892 835 91.5 0.249 0.328 0.043 57 6.4 . . 'X-RAY DIFFRACTION' . 6.60 19.60 1023 890 840 87.0 0.269 0.254 0.036 50 5.6 . . 'X-RAY DIFFRACTION' . # _struct.entry_id 1T7X _struct.title 'Zn-alpha-2-glycoprotein; refolded CHO-ZAG PEG 400' _struct.pdbx_descriptor Zinc-alpha-2-glycoprotein _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 1T7X _struct_keywords.pdbx_keywords 'LIPID BINDING PROTEIN' _struct_keywords.text 'MHC class I homolog, LIPID BINDING PROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 2 ? # _struct_biol.id 1 _struct_biol.pdbx_parent_biol_id ? _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 GLY A 52 ? GLN A 56 ? GLY A 52 GLN A 56 5 ? 5 HELX_P HELX_P2 2 ASP A 62 ? TYR A 88 ? ASP A 62 TYR A 88 1 ? 27 HELX_P HELX_P3 3 ALA A 140 ? TRP A 148 ? ALA A 140 TRP A 148 1 ? 9 HELX_P HELX_P4 4 PRO A 152 ? GLU A 164 ? PRO A 152 GLU A 164 1 ? 13 HELX_P HELX_P5 5 GLU A 164 ? SER A 177 ? GLU A 164 SER A 177 1 ? 14 HELX_P HELX_P6 6 SER A 177 ? ASP A 182 ? SER A 177 ASP A 182 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 205 SG ? ? ? 1_555 A CYS 260 SG ? ? A CYS 205 A CYS 260 1_555 ? ? ? ? ? ? ? 2.027 ? covale1 covale ? ? A ASN 108 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 108 A NAG 310 1_555 ? ? ? ? ? ? ? 1.455 ? covale2 covale ? ? A ASN 239 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 239 A NAG 320 1_555 ? ? ? ? ? ? ? 1.456 ? covale3 covale ? ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 320 A NAG 321 1_555 ? ? ? ? ? ? ? 1.382 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ILE 131 A . ? ILE 131 A PRO 132 A ? PRO 132 A 1 -0.34 2 TYR 211 A . ? TYR 211 A PRO 212 A ? PRO 212 A 1 -0.07 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 8 ? B ? 4 ? C ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel A 4 5 ? anti-parallel A 5 6 ? anti-parallel A 6 7 ? anti-parallel A 7 8 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel C 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 GLN A 49 ? PRO A 50 ? GLN A 49 PRO A 50 A 2 LEU A 36 ? ASN A 42 ? LEU A 36 ASN A 42 A 3 PHE A 27 ? LEU A 33 ? PHE A 27 LEU A 33 A 4 ARG A 7 ? LEU A 17 ? ARG A 7 LEU A 17 A 5 VAL A 96 ? GLU A 106 ? VAL A 96 GLU A 106 A 6 SER A 110 ? TYR A 119 ? SER A 110 TYR A 119 A 7 LYS A 122 ? ASN A 128 ? LYS A 122 ASN A 128 A 8 ALA A 133 ? PRO A 136 ? ALA A 133 PRO A 136 B 1 SER A 188 ? GLN A 195 ? SER A 188 GLN A 195 B 2 LYS A 201 ? PHE A 210 ? LYS A 201 PHE A 210 B 3 THR A 241 ? VAL A 250 ? THR A 241 VAL A 250 B 4 LEU A 230 ? HIS A 236 ? LEU A 230 HIS A 236 C 1 GLU A 224 ? VAL A 225 ? GLU A 224 VAL A 225 C 2 ASP A 216 ? ARG A 221 ? ASP A 216 ARG A 221 C 3 TYR A 258 ? GLN A 263 ? TYR A 258 GLN A 263 C 4 LEU A 271 ? PRO A 274 ? LEU A 271 PRO A 274 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 O GLN A 49 ? O GLN A 49 N ARG A 40 ? N ARG A 40 A 2 3 O LEU A 36 ? O LEU A 36 N LEU A 33 ? N LEU A 33 A 3 4 O GLN A 28 ? O GLN A 28 N THR A 15 ? N THR A 15 A 4 5 N LEU A 10 ? N LEU A 10 O CYS A 103 ? O CYS A 103 A 5 6 N GLN A 98 ? N GLN A 98 O TYR A 118 ? O TYR A 118 A 6 7 N TYR A 117 ? N TYR A 117 O ILE A 125 ? O ILE A 125 A 7 8 N GLU A 126 ? N GLU A 126 O VAL A 135 ? O VAL A 135 B 1 2 N THR A 192 ? N THR A 192 O LYS A 204 ? O LYS A 204 B 2 3 N PHE A 210 ? N PHE A 210 O TYR A 242 ? O TYR A 242 B 3 4 O THR A 241 ? O THR A 241 N HIS A 236 ? N HIS A 236 C 1 2 O GLU A 224 ? O GLU A 224 N ARG A 221 ? N ARG A 221 C 2 3 N HIS A 218 ? N HIS A 218 O HIS A 261 ? O HIS A 261 C 3 4 N CYS A 260 ? N CYS A 260 O VAL A 273 ? O VAL A 273 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 310' AC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 320' AC3 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 321' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 2 ASN A 108 ? ASN A 108 . ? 1_555 ? 2 AC1 2 ARG A 171 ? ARG A 171 . ? 1_555 ? 3 AC2 3 ASP A 209 ? ASP A 209 . ? 1_555 ? 4 AC2 3 ASN A 239 ? ASN A 239 . ? 1_555 ? 5 AC2 3 NAG D . ? NAG A 321 . ? 1_555 ? 6 AC3 2 GLN A 243 ? GLN A 243 . ? 1_555 ? 7 AC3 2 NAG C . ? NAG A 320 . ? 1_555 ? # _atom_sites.entry_id 1T7X _atom_sites.fract_transf_matrix[1][1] 0.008147 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.008147 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.015355 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASP A 1 5 ? 18.731 79.166 1.580 1.00 94.50 ? 5 ASP A N 1 ATOM 2 C CA . ASP A 1 5 ? 18.082 79.298 2.915 1.00 92.68 ? 5 ASP A CA 1 ATOM 3 C C . ASP A 1 5 ? 18.075 77.963 3.653 1.00 91.11 ? 5 ASP A C 1 ATOM 4 O O . ASP A 1 5 ? 18.188 76.902 3.036 1.00 96.94 ? 5 ASP A O 1 ATOM 5 C CB . ASP A 1 5 ? 16.645 79.796 2.753 1.00 85.05 ? 5 ASP A CB 1 ATOM 6 C CG . ASP A 1 5 ? 16.574 81.223 2.249 1.00 91.72 ? 5 ASP A CG 1 ATOM 7 O OD1 . ASP A 1 5 ? 16.828 82.151 3.047 1.00 91.57 ? 5 ASP A OD1 1 ATOM 8 O OD2 . ASP A 1 5 ? 16.266 81.413 1.051 1.00 89.49 ? 5 ASP A OD2 1 ATOM 9 N N . GLY A 1 6 ? 17.941 78.028 4.978 1.00 62.99 ? 6 GLY A N 1 ATOM 10 C CA . GLY A 1 6 ? 17.919 76.825 5.792 1.00 49.39 ? 6 GLY A CA 1 ATOM 11 C C . GLY A 1 6 ? 16.688 76.767 6.674 1.00 41.01 ? 6 GLY A C 1 ATOM 12 O O . GLY A 1 6 ? 15.666 77.365 6.345 1.00 33.88 ? 6 GLY A O 1 ATOM 13 N N . ARG A 1 7 ? 16.796 76.060 7.795 1.00 38.97 ? 7 ARG A N 1 ATOM 14 C CA . ARG A 1 7 ? 15.692 75.905 8.739 1.00 36.20 ? 7 ARG A CA 1 ATOM 15 C C . ARG A 1 7 ? 15.526 77.097 9.679 1.00 31.06 ? 7 ARG A C 1 ATOM 16 O O . ARG A 1 7 ? 16.500 77.720 10.073 1.00 27.01 ? 7 ARG A O 1 ATOM 17 C CB . ARG A 1 7 ? 15.908 74.650 9.588 1.00 92.74 ? 7 ARG A CB 1 ATOM 18 C CG . ARG A 1 7 ? 16.013 73.361 8.803 1.00 105.19 ? 7 ARG A CG 1 ATOM 19 C CD . ARG A 1 7 ? 14.733 72.554 8.900 1.00 125.12 ? 7 ARG A CD 1 ATOM 20 N NE . ARG A 1 7 ? 14.498 72.057 10.252 1.00 132.81 ? 7 ARG A NE 1 ATOM 21 C CZ . ARG A 1 7 ? 13.454 71.311 10.600 1.00 138.59 ? 7 ARG A CZ 1 ATOM 22 N NH1 . ARG A 1 7 ? 12.544 70.972 9.696 1.00 133.87 ? 7 ARG A NH1 1 ATOM 23 N NH2 . ARG A 1 7 ? 13.320 70.900 11.854 1.00 137.64 ? 7 ARG A NH2 1 ATOM 24 N N . TYR A 1 8 ? 14.283 77.407 10.029 1.00 13.35 ? 8 TYR A N 1 ATOM 25 C CA . TYR A 1 8 ? 13.971 78.482 10.964 1.00 13.35 ? 8 TYR A CA 1 ATOM 26 C C . TYR A 1 8 ? 12.644 78.146 11.602 1.00 13.35 ? 8 TYR A C 1 ATOM 27 O O . TYR A 1 8 ? 11.705 77.747 10.915 1.00 13.35 ? 8 TYR A O 1 ATOM 28 C CB . TYR A 1 8 ? 13.842 79.822 10.263 1.00 36.05 ? 8 TYR A CB 1 ATOM 29 C CG . TYR A 1 8 ? 15.121 80.339 9.681 1.00 43.48 ? 8 TYR A CG 1 ATOM 30 C CD1 . TYR A 1 8 ? 16.119 80.889 10.488 1.00 39.19 ? 8 TYR A CD1 1 ATOM 31 C CD2 . TYR A 1 8 ? 15.341 80.279 8.311 1.00 37.79 ? 8 TYR A CD2 1 ATOM 32 C CE1 . TYR A 1 8 ? 17.304 81.368 9.927 1.00 38.79 ? 8 TYR A CE1 1 ATOM 33 C CE2 . TYR A 1 8 ? 16.515 80.748 7.748 1.00 45.89 ? 8 TYR A CE2 1 ATOM 34 C CZ . TYR A 1 8 ? 17.484 81.287 8.552 1.00 43.85 ? 8 TYR A CZ 1 ATOM 35 O OH . TYR A 1 8 ? 18.625 81.724 7.948 1.00 40.69 ? 8 TYR A OH 1 ATOM 36 N N . SER A 1 9 ? 12.560 78.311 12.915 1.00 13.64 ? 9 SER A N 1 ATOM 37 C CA . SER A 1 9 ? 11.327 78.018 13.626 1.00 13.64 ? 9 SER A CA 1 ATOM 38 C C . SER A 1 9 ? 10.922 79.109 14.604 1.00 13.64 ? 9 SER A C 1 ATOM 39 O O . SER A 1 9 ? 11.743 79.861 15.099 1.00 13.91 ? 9 SER A O 1 ATOM 40 C CB . SER A 1 9 ? 11.468 76.691 14.351 1.00 11.86 ? 9 SER A CB 1 ATOM 41 O OG . SER A 1 9 ? 12.747 76.596 14.937 1.00 21.53 ? 9 SER A OG 1 ATOM 42 N N . LEU A 1 10 ? 9.632 79.203 14.862 1.00 10.31 ? 10 LEU A N 1 ATOM 43 C CA . LEU A 1 10 ? 9.116 80.189 15.786 1.00 10.31 ? 10 LEU A CA 1 ATOM 44 C C . LEU A 1 10 ? 8.278 79.428 16.804 1.00 10.31 ? 10 LEU A C 1 ATOM 45 O O . LEU A 1 10 ? 7.313 78.757 16.446 1.00 10.31 ? 10 LEU A O 1 ATOM 46 C CB . LEU A 1 10 ? 8.256 81.199 15.034 1.00 4.76 ? 10 LEU A CB 1 ATOM 47 C CG . LEU A 1 10 ? 7.542 82.227 15.902 1.00 4.76 ? 10 LEU A CG 1 ATOM 48 C CD1 . LEU A 1 10 ? 8.541 83.183 16.486 1.00 4.76 ? 10 LEU A CD1 1 ATOM 49 C CD2 . LEU A 1 10 ? 6.520 82.970 15.072 1.00 4.76 ? 10 LEU A CD2 1 ATOM 50 N N . THR A 1 11 ? 8.646 79.520 18.073 1.00 8.41 ? 11 THR A N 1 ATOM 51 C CA . THR A 1 11 ? 7.905 78.797 19.094 1.00 8.41 ? 11 THR A CA 1 ATOM 52 C C . THR A 1 11 ? 7.526 79.637 20.301 1.00 8.41 ? 11 THR A C 1 ATOM 53 O O . THR A 1 11 ? 8.308 80.447 20.787 1.00 8.41 ? 11 THR A O 1 ATOM 54 C CB . THR A 1 11 ? 8.701 77.569 19.608 1.00 11.26 ? 11 THR A CB 1 ATOM 55 O OG1 . THR A 1 11 ? 9.127 76.753 18.508 1.00 11.26 ? 11 THR A OG1 1 ATOM 56 C CG2 . THR A 1 11 ? 7.832 76.729 20.502 1.00 11.26 ? 11 THR A CG2 1 ATOM 57 N N . TYR A 1 12 ? 6.305 79.432 20.775 1.00 10.77 ? 12 TYR A N 1 ATOM 58 C CA . TYR A 1 12 ? 5.805 80.122 21.945 1.00 10.77 ? 12 TYR A CA 1 ATOM 59 C C . TYR A 1 12 ? 5.330 79.072 22.927 1.00 10.77 ? 12 TYR A C 1 ATOM 60 O O . TYR A 1 12 ? 4.709 78.087 22.537 1.00 10.77 ? 12 TYR A O 1 ATOM 61 C CB . TYR A 1 12 ? 4.635 81.013 21.597 1.00 7.12 ? 12 TYR A CB 1 ATOM 62 C CG . TYR A 1 12 ? 4.942 82.089 20.592 1.00 7.12 ? 12 TYR A CG 1 ATOM 63 C CD1 . TYR A 1 12 ? 4.883 81.838 19.229 1.00 7.12 ? 12 TYR A CD1 1 ATOM 64 C CD2 . TYR A 1 12 ? 5.225 83.380 21.004 1.00 7.12 ? 12 TYR A CD2 1 ATOM 65 C CE1 . TYR A 1 12 ? 5.080 82.849 18.308 1.00 7.12 ? 12 TYR A CE1 1 ATOM 66 C CE2 . TYR A 1 12 ? 5.428 84.387 20.093 1.00 7.12 ? 12 TYR A CE2 1 ATOM 67 C CZ . TYR A 1 12 ? 5.347 84.120 18.750 1.00 7.12 ? 12 TYR A CZ 1 ATOM 68 O OH . TYR A 1 12 ? 5.482 85.155 17.858 1.00 7.12 ? 12 TYR A OH 1 ATOM 69 N N . ILE A 1 13 ? 5.627 79.283 24.204 1.00 21.48 ? 13 ILE A N 1 ATOM 70 C CA . ILE A 1 13 ? 5.212 78.359 25.244 1.00 21.48 ? 13 ILE A CA 1 ATOM 71 C C . ILE A 1 13 ? 4.533 79.116 26.374 1.00 21.48 ? 13 ILE A C 1 ATOM 72 O O . ILE A 1 13 ? 5.087 80.072 26.924 1.00 21.48 ? 13 ILE A O 1 ATOM 73 C CB . ILE A 1 13 ? 6.404 77.578 25.786 1.00 13.10 ? 13 ILE A CB 1 ATOM 74 C CG1 . ILE A 1 13 ? 7.003 76.739 24.658 1.00 13.10 ? 13 ILE A CG1 1 ATOM 75 C CG2 . ILE A 1 13 ? 5.973 76.707 26.950 1.00 13.10 ? 13 ILE A CG2 1 ATOM 76 C CD1 . ILE A 1 13 ? 8.047 75.763 25.128 1.00 16.99 ? 13 ILE A CD1 1 ATOM 77 N N . TYR A 1 14 ? 3.319 78.683 26.703 1.00 9.05 ? 14 TYR A N 1 ATOM 78 C CA . TYR A 1 14 ? 2.524 79.309 27.753 1.00 9.05 ? 14 TYR A CA 1 ATOM 79 C C . TYR A 1 14 ? 2.365 78.382 28.937 1.00 9.05 ? 14 TYR A C 1 ATOM 80 O O . TYR A 1 14 ? 2.065 77.209 28.768 1.00 9.05 ? 14 TYR A O 1 ATOM 81 C CB . TYR A 1 14 ? 1.140 79.682 27.219 1.00 24.91 ? 14 TYR A CB 1 ATOM 82 C CG . TYR A 1 14 ? 1.150 80.795 26.200 1.00 24.91 ? 14 TYR A CG 1 ATOM 83 C CD1 . TYR A 1 14 ? 1.929 80.714 25.061 1.00 24.91 ? 14 TYR A CD1 1 ATOM 84 C CD2 . TYR A 1 14 ? 0.402 81.938 26.389 1.00 24.91 ? 14 TYR A CD2 1 ATOM 85 C CE1 . TYR A 1 14 ? 1.968 81.749 24.141 1.00 24.91 ? 14 TYR A CE1 1 ATOM 86 C CE2 . TYR A 1 14 ? 0.434 82.980 25.473 1.00 24.91 ? 14 TYR A CE2 1 ATOM 87 C CZ . TYR A 1 14 ? 1.222 82.881 24.353 1.00 24.91 ? 14 TYR A CZ 1 ATOM 88 O OH . TYR A 1 14 ? 1.292 83.924 23.458 1.00 26.98 ? 14 TYR A OH 1 ATOM 89 N N . THR A 1 15 ? 2.589 78.920 30.132 1.00 4.65 ? 15 THR A N 1 ATOM 90 C CA . THR A 1 15 ? 2.453 78.169 31.369 1.00 4.65 ? 15 THR A CA 1 ATOM 91 C C . THR A 1 15 ? 1.550 78.941 32.303 1.00 4.65 ? 15 THR A C 1 ATOM 92 O O . THR A 1 15 ? 1.810 80.099 32.584 1.00 4.65 ? 15 THR A O 1 ATOM 93 C CB . THR A 1 15 ? 3.766 78.022 32.062 1.00 7.33 ? 15 THR A CB 1 ATOM 94 O OG1 . THR A 1 15 ? 4.729 77.529 31.141 1.00 7.33 ? 15 THR A OG1 1 ATOM 95 C CG2 . THR A 1 15 ? 3.642 77.058 33.188 1.00 7.33 ? 15 THR A CG2 1 ATOM 96 N N . GLY A 1 16 ? 0.487 78.299 32.775 1.00 13.17 ? 16 GLY A N 1 ATOM 97 C CA . GLY A 1 16 ? -0.440 78.946 33.687 1.00 13.17 ? 16 GLY A CA 1 ATOM 98 C C . GLY A 1 16 ? -0.642 78.082 34.909 1.00 13.17 ? 16 GLY A C 1 ATOM 99 O O . GLY A 1 16 ? -0.743 76.863 34.781 1.00 13.17 ? 16 GLY A O 1 ATOM 100 N N . LEU A 1 17 ? -0.690 78.695 36.093 1.00 14.98 ? 17 LEU A N 1 ATOM 101 C CA . LEU A 1 17 ? -0.874 77.961 37.352 1.00 14.98 ? 17 LEU A CA 1 ATOM 102 C C . LEU A 1 17 ? -2.190 78.378 38.016 1.00 14.98 ? 17 LEU A C 1 ATOM 103 O O . LEU A 1 17 ? -2.446 79.565 38.192 1.00 14.98 ? 17 LEU A O 1 ATOM 104 C CB . LEU A 1 17 ? 0.305 78.244 38.286 1.00 7.05 ? 17 LEU A CB 1 ATOM 105 C CG . LEU A 1 17 ? 1.712 77.905 37.775 1.00 7.05 ? 17 LEU A CG 1 ATOM 106 C CD1 . LEU A 1 17 ? 2.737 78.745 38.484 1.00 7.05 ? 17 LEU A CD1 1 ATOM 107 C CD2 . LEU A 1 17 ? 2.009 76.452 37.982 1.00 7.05 ? 17 LEU A CD2 1 ATOM 108 N N . SER A 1 18 ? -3.018 77.406 38.393 1.00 15.42 ? 18 SER A N 1 ATOM 109 C CA . SER A 1 18 ? -4.312 77.707 38.997 1.00 15.42 ? 18 SER A CA 1 ATOM 110 C C . SER A 1 18 ? -4.183 78.338 40.358 1.00 22.62 ? 18 SER A C 1 ATOM 111 O O . SER A 1 18 ? -4.922 79.261 40.686 1.00 19.54 ? 18 SER A O 1 ATOM 112 C CB . SER A 1 18 ? -5.158 76.449 39.124 1.00 31.18 ? 18 SER A CB 1 ATOM 113 O OG . SER A 1 18 ? -4.758 75.689 40.244 1.00 31.18 ? 18 SER A OG 1 ATOM 114 N N . LYS A 1 19 ? -3.248 77.824 41.151 1.00 19.11 ? 19 LYS A N 1 ATOM 115 C CA . LYS A 1 19 ? -2.999 78.332 42.502 1.00 20.26 ? 19 LYS A CA 1 ATOM 116 C C . LYS A 1 19 ? -1.494 78.545 42.664 1.00 19.11 ? 19 LYS A C 1 ATOM 117 O O . LYS A 1 19 ? -0.766 77.639 43.046 1.00 20.84 ? 19 LYS A O 1 ATOM 118 C CB . LYS A 1 19 ? -3.531 77.328 43.533 1.00 54.45 ? 19 LYS A CB 1 ATOM 119 C CG . LYS A 1 19 ? -3.386 77.753 44.982 1.00 70.04 ? 19 LYS A CG 1 ATOM 120 C CD . LYS A 1 19 ? -4.221 76.868 45.897 1.00 71.33 ? 19 LYS A CD 1 ATOM 121 C CE . LYS A 1 19 ? -5.664 77.339 45.969 1.00 81.22 ? 19 LYS A CE 1 ATOM 122 N NZ . LYS A 1 19 ? -6.284 77.480 44.626 1.00 94.59 ? 19 LYS A NZ 1 ATOM 123 N N . HIS A 1 20 ? -1.035 79.756 42.376 1.00 10.10 ? 20 HIS A N 1 ATOM 124 C CA . HIS A 1 20 ? 0.383 80.069 42.437 1.00 9.75 ? 20 HIS A CA 1 ATOM 125 C C . HIS A 1 20 ? 0.922 80.536 43.789 1.00 15.09 ? 20 HIS A C 1 ATOM 126 O O . HIS A 1 20 ? 0.302 81.331 44.486 1.00 9.75 ? 20 HIS A O 1 ATOM 127 C CB . HIS A 1 20 ? 0.714 81.106 41.347 1.00 20.16 ? 20 HIS A CB 1 ATOM 128 C CG . HIS A 1 20 ? 0.374 82.521 41.719 1.00 26.47 ? 20 HIS A CG 1 ATOM 129 N ND1 . HIS A 1 20 ? 1.250 83.347 42.393 1.00 34.64 ? 20 HIS A ND1 1 ATOM 130 C CD2 . HIS A 1 20 ? -0.739 83.261 41.498 1.00 31.26 ? 20 HIS A CD2 1 ATOM 131 C CE1 . HIS A 1 20 ? 0.694 84.531 42.567 1.00 36.49 ? 20 HIS A CE1 1 ATOM 132 N NE2 . HIS A 1 20 ? -0.513 84.506 42.033 1.00 33.47 ? 20 HIS A NE2 1 ATOM 133 N N . VAL A 1 21 ? 2.094 80.028 44.141 1.00 21.26 ? 21 VAL A N 1 ATOM 134 C CA . VAL A 1 21 ? 2.768 80.389 45.377 1.00 23.18 ? 21 VAL A CA 1 ATOM 135 C C . VAL A 1 21 ? 3.348 81.792 45.220 1.00 25.57 ? 21 VAL A C 1 ATOM 136 O O . VAL A 1 21 ? 3.431 82.305 44.110 1.00 19.86 ? 21 VAL A O 1 ATOM 137 C CB . VAL A 1 21 ? 3.931 79.426 45.678 1.00 9.55 ? 21 VAL A CB 1 ATOM 138 C CG1 . VAL A 1 21 ? 3.415 78.015 45.783 1.00 9.55 ? 21 VAL A CG1 1 ATOM 139 C CG2 . VAL A 1 21 ? 4.997 79.538 44.591 1.00 10.91 ? 21 VAL A CG2 1 ATOM 140 N N . GLU A 1 22 ? 3.773 82.394 46.326 1.00 35.41 ? 22 GLU A N 1 ATOM 141 C CA . GLU A 1 22 ? 4.329 83.742 46.299 1.00 37.50 ? 22 GLU A CA 1 ATOM 142 C C . GLU A 1 22 ? 5.634 83.849 45.515 1.00 25.29 ? 22 GLU A C 1 ATOM 143 O O . GLU A 1 22 ? 6.512 82.992 45.630 1.00 34.68 ? 22 GLU A O 1 ATOM 144 C CB . GLU A 1 22 ? 4.549 84.237 47.730 1.00 102.31 ? 22 GLU A CB 1 ATOM 145 C CG . GLU A 1 22 ? 3.310 84.145 48.613 1.00 130.98 ? 22 GLU A CG 1 ATOM 146 C CD . GLU A 1 22 ? 2.151 84.971 48.086 1.00 142.49 ? 22 GLU A CD 1 ATOM 147 O OE1 . GLU A 1 22 ? 2.283 86.211 48.032 1.00 148.83 ? 22 GLU A OE1 1 ATOM 148 O OE2 . GLU A 1 22 ? 1.111 84.380 47.724 1.00 149.26 ? 22 GLU A OE2 1 ATOM 149 N N . ASP A 1 23 ? 5.746 84.910 44.717 1.00 26.78 ? 23 ASP A N 1 ATOM 150 C CA . ASP A 1 23 ? 6.930 85.186 43.902 1.00 31.63 ? 23 ASP A CA 1 ATOM 151 C C . ASP A 1 23 ? 7.017 84.426 42.577 1.00 27.88 ? 23 ASP A C 1 ATOM 152 O O . ASP A 1 23 ? 8.043 84.476 41.888 1.00 29.47 ? 23 ASP A O 1 ATOM 153 C CB . ASP A 1 23 ? 8.205 84.961 44.718 1.00 90.59 ? 23 ASP A CB 1 ATOM 154 C CG . ASP A 1 23 ? 8.374 85.989 45.821 1.00 107.21 ? 23 ASP A CG 1 ATOM 155 O OD1 . ASP A 1 23 ? 8.358 87.199 45.507 1.00 104.90 ? 23 ASP A OD1 1 ATOM 156 O OD2 . ASP A 1 23 ? 8.523 85.591 46.996 1.00 111.59 ? 23 ASP A OD2 1 ATOM 157 N N . VAL A 1 24 ? 5.939 83.730 42.220 1.00 33.09 ? 24 VAL A N 1 ATOM 158 C CA . VAL A 1 24 ? 5.871 82.979 40.966 1.00 26.16 ? 24 VAL A CA 1 ATOM 159 C C . VAL A 1 24 ? 4.625 83.430 40.217 1.00 26.16 ? 24 VAL A C 1 ATOM 160 O O . VAL A 1 24 ? 3.509 83.158 40.639 1.00 26.16 ? 24 VAL A O 1 ATOM 161 C CB . VAL A 1 24 ? 5.767 81.468 41.217 1.00 19.27 ? 24 VAL A CB 1 ATOM 162 C CG1 . VAL A 1 24 ? 5.595 80.744 39.914 1.00 19.27 ? 24 VAL A CG1 1 ATOM 163 C CG2 . VAL A 1 24 ? 6.999 80.972 41.920 1.00 19.27 ? 24 VAL A CG2 1 ATOM 164 N N . PRO A 1 25 ? 4.800 84.139 39.099 1.00 17.00 ? 25 PRO A N 1 ATOM 165 C CA . PRO A 1 25 ? 3.663 84.613 38.321 1.00 17.00 ? 25 PRO A CA 1 ATOM 166 C C . PRO A 1 25 ? 2.762 83.480 37.888 1.00 17.00 ? 25 PRO A C 1 ATOM 167 O O . PRO A 1 25 ? 3.245 82.424 37.484 1.00 17.00 ? 25 PRO A O 1 ATOM 168 C CB . PRO A 1 25 ? 4.325 85.304 37.137 1.00 4.65 ? 25 PRO A CB 1 ATOM 169 C CG . PRO A 1 25 ? 5.591 84.569 37.002 1.00 15.67 ? 25 PRO A CG 1 ATOM 170 C CD . PRO A 1 25 ? 6.053 84.458 38.409 1.00 4.65 ? 25 PRO A CD 1 ATOM 171 N N . ALA A 1 26 ? 1.455 83.699 37.963 1.00 22.81 ? 26 ALA A N 1 ATOM 172 C CA . ALA A 1 26 ? 0.498 82.683 37.569 1.00 22.81 ? 26 ALA A CA 1 ATOM 173 C C . ALA A 1 26 ? 0.581 82.358 36.085 1.00 22.81 ? 26 ALA A C 1 ATOM 174 O O . ALA A 1 26 ? 0.282 81.242 35.677 1.00 22.81 ? 26 ALA A O 1 ATOM 175 C CB . ALA A 1 26 ? -0.883 83.141 37.887 1.00 4.65 ? 26 ALA A CB 1 ATOM 176 N N . PHE A 1 27 ? 0.991 83.332 35.279 1.00 15.55 ? 27 PHE A N 1 ATOM 177 C CA . PHE A 1 27 ? 1.057 83.138 33.843 1.00 15.55 ? 27 PHE A CA 1 ATOM 178 C C . PHE A 1 27 ? 2.346 83.649 33.206 1.00 15.55 ? 27 PHE A C 1 ATOM 179 O O . PHE A 1 27 ? 2.690 84.823 33.309 1.00 15.55 ? 27 PHE A O 1 ATOM 180 C CB . PHE A 1 27 ? -0.153 83.823 33.202 1.00 13.89 ? 27 PHE A CB 1 ATOM 181 C CG . PHE A 1 27 ? -0.202 83.709 31.716 1.00 13.89 ? 27 PHE A CG 1 ATOM 182 C CD1 . PHE A 1 27 ? -0.707 82.568 31.111 1.00 13.89 ? 27 PHE A CD1 1 ATOM 183 C CD2 . PHE A 1 27 ? 0.282 84.734 30.918 1.00 13.89 ? 27 PHE A CD2 1 ATOM 184 C CE1 . PHE A 1 27 ? -0.726 82.453 29.731 1.00 13.89 ? 27 PHE A CE1 1 ATOM 185 C CE2 . PHE A 1 27 ? 0.269 84.631 29.538 1.00 13.89 ? 27 PHE A CE2 1 ATOM 186 C CZ . PHE A 1 27 ? -0.235 83.492 28.944 1.00 13.89 ? 27 PHE A CZ 1 ATOM 187 N N . GLN A 1 28 ? 3.061 82.748 32.546 1.00 11.87 ? 28 GLN A N 1 ATOM 188 C CA . GLN A 1 28 ? 4.291 83.096 31.871 1.00 11.87 ? 28 GLN A CA 1 ATOM 189 C C . GLN A 1 28 ? 4.165 82.723 30.403 1.00 11.87 ? 28 GLN A C 1 ATOM 190 O O . GLN A 1 28 ? 3.480 81.766 30.038 1.00 11.87 ? 28 GLN A O 1 ATOM 191 C CB . GLN A 1 28 ? 5.478 82.374 32.518 1.00 39.39 ? 28 GLN A CB 1 ATOM 192 C CG . GLN A 1 28 ? 6.062 83.156 33.680 1.00 43.87 ? 28 GLN A CG 1 ATOM 193 C CD . GLN A 1 28 ? 6.694 82.288 34.752 1.00 50.45 ? 28 GLN A CD 1 ATOM 194 O OE1 . GLN A 1 28 ? 6.035 81.418 35.332 1.00 56.07 ? 28 GLN A OE1 1 ATOM 195 N NE2 . GLN A 1 28 ? 7.972 82.533 35.039 1.00 48.17 ? 28 GLN A NE2 1 ATOM 196 N N . ALA A 1 29 ? 4.823 83.503 29.559 1.00 10.14 ? 29 ALA A N 1 ATOM 197 C CA . ALA A 1 29 ? 4.820 83.279 28.126 1.00 10.14 ? 29 ALA A CA 1 ATOM 198 C C . ALA A 1 29 ? 6.242 83.522 27.656 1.00 10.14 ? 29 ALA A C 1 ATOM 199 O O . ALA A 1 29 ? 6.953 84.337 28.230 1.00 10.14 ? 29 ALA A O 1 ATOM 200 C CB . ALA A 1 29 ? 3.869 84.252 27.460 1.00 4.65 ? 29 ALA A CB 1 ATOM 201 N N . LEU A 1 30 ? 6.681 82.811 26.634 1.00 14.39 ? 30 LEU A N 1 ATOM 202 C CA . LEU A 1 30 ? 8.026 83.041 26.150 1.00 14.39 ? 30 LEU A CA 1 ATOM 203 C C . LEU A 1 30 ? 8.078 82.670 24.694 1.00 14.39 ? 30 LEU A C 1 ATOM 204 O O . LEU A 1 30 ? 7.191 81.973 24.206 1.00 14.39 ? 30 LEU A O 1 ATOM 205 C CB . LEU A 1 30 ? 9.031 82.222 26.962 1.00 35.05 ? 30 LEU A CB 1 ATOM 206 C CG . LEU A 1 30 ? 9.136 80.699 26.858 1.00 43.24 ? 30 LEU A CG 1 ATOM 207 C CD1 . LEU A 1 30 ? 9.892 80.314 25.598 1.00 43.80 ? 30 LEU A CD1 1 ATOM 208 C CD2 . LEU A 1 30 ? 9.873 80.173 28.067 1.00 42.91 ? 30 LEU A CD2 1 ATOM 209 N N . GLY A 1 31 ? 9.102 83.142 23.995 1.00 24.16 ? 31 GLY A N 1 ATOM 210 C CA . GLY A 1 31 ? 9.222 82.847 22.579 1.00 24.16 ? 31 GLY A CA 1 ATOM 211 C C . GLY A 1 31 ? 10.660 82.644 22.157 1.00 24.16 ? 31 GLY A C 1 ATOM 212 O O . GLY A 1 31 ? 11.548 83.396 22.561 1.00 24.16 ? 31 GLY A O 1 ATOM 213 N N . SER A 1 32 ? 10.896 81.626 21.339 1.00 23.76 ? 32 SER A N 1 ATOM 214 C CA . SER A 1 32 ? 12.237 81.324 20.880 1.00 23.76 ? 32 SER A CA 1 ATOM 215 C C . SER A 1 32 ? 12.295 81.252 19.375 1.00 23.76 ? 32 SER A C 1 ATOM 216 O O . SER A 1 32 ? 11.381 80.730 18.730 1.00 23.76 ? 32 SER A O 1 ATOM 217 C CB . SER A 1 32 ? 12.704 79.981 21.435 1.00 25.59 ? 32 SER A CB 1 ATOM 218 O OG . SER A 1 32 ? 12.884 80.018 22.836 1.00 30.75 ? 32 SER A OG 1 ATOM 219 N N . LEU A 1 33 ? 13.371 81.793 18.815 1.00 14.27 ? 33 LEU A N 1 ATOM 220 C CA . LEU A 1 33 ? 13.595 81.741 17.378 1.00 14.27 ? 33 LEU A CA 1 ATOM 221 C C . LEU A 1 33 ? 14.758 80.788 17.272 1.00 14.27 ? 33 LEU A C 1 ATOM 222 O O . LEU A 1 33 ? 15.806 81.037 17.844 1.00 14.27 ? 33 LEU A O 1 ATOM 223 C CB . LEU A 1 33 ? 13.974 83.114 16.824 1.00 8.52 ? 33 LEU A CB 1 ATOM 224 C CG . LEU A 1 33 ? 12.842 83.994 16.298 1.00 8.52 ? 33 LEU A CG 1 ATOM 225 C CD1 . LEU A 1 33 ? 13.353 85.380 16.043 1.00 8.52 ? 33 LEU A CD1 1 ATOM 226 C CD2 . LEU A 1 33 ? 12.296 83.398 15.025 1.00 8.52 ? 33 LEU A CD2 1 ATOM 227 N N . ASN A 1 34 ? 14.564 79.686 16.562 1.00 23.97 ? 34 ASN A N 1 ATOM 228 C CA . ASN A 1 34 ? 15.602 78.681 16.428 1.00 23.97 ? 34 ASN A CA 1 ATOM 229 C C . ASN A 1 34 ? 16.071 78.280 17.806 1.00 23.97 ? 34 ASN A C 1 ATOM 230 O O . ASN A 1 34 ? 15.263 77.880 18.627 1.00 23.97 ? 34 ASN A O 1 ATOM 231 C CB . ASN A 1 34 ? 16.773 79.201 15.609 1.00 27.23 ? 34 ASN A CB 1 ATOM 232 C CG . ASN A 1 34 ? 16.500 79.157 14.134 1.00 34.59 ? 34 ASN A CG 1 ATOM 233 O OD1 . ASN A 1 34 ? 15.747 78.311 13.665 1.00 29.30 ? 34 ASN A OD1 1 ATOM 234 N ND2 . ASN A 1 34 ? 17.123 80.053 13.386 1.00 27.80 ? 34 ASN A ND2 1 ATOM 235 N N . ASP A 1 35 ? 17.359 78.423 18.086 1.00 10.27 ? 35 ASP A N 1 ATOM 236 C CA . ASP A 1 35 ? 17.879 78.016 19.389 1.00 10.27 ? 35 ASP A CA 1 ATOM 237 C C . ASP A 1 35 ? 17.960 79.119 20.442 1.00 10.27 ? 35 ASP A C 1 ATOM 238 O O . ASP A 1 35 ? 18.503 78.897 21.527 1.00 10.27 ? 35 ASP A O 1 ATOM 239 C CB . ASP A 1 35 ? 19.262 77.388 19.206 1.00 20.22 ? 35 ASP A CB 1 ATOM 240 C CG . ASP A 1 35 ? 20.307 78.392 18.734 1.00 24.69 ? 35 ASP A CG 1 ATOM 241 O OD1 . ASP A 1 35 ? 19.928 79.407 18.110 1.00 20.22 ? 35 ASP A OD1 1 ATOM 242 O OD2 . ASP A 1 35 ? 21.513 78.157 18.976 1.00 20.22 ? 35 ASP A OD2 1 ATOM 243 N N . LEU A 1 36 ? 17.406 80.291 20.138 1.00 11.63 ? 36 LEU A N 1 ATOM 244 C CA . LEU A 1 36 ? 17.465 81.429 21.053 1.00 11.63 ? 36 LEU A CA 1 ATOM 245 C C . LEU A 1 36 ? 16.112 82.030 21.422 1.00 11.63 ? 36 LEU A C 1 ATOM 246 O O . LEU A 1 36 ? 15.213 82.138 20.583 1.00 11.63 ? 36 LEU A O 1 ATOM 247 C CB . LEU A 1 36 ? 18.336 82.515 20.430 1.00 12.50 ? 36 LEU A CB 1 ATOM 248 C CG . LEU A 1 36 ? 19.677 82.002 19.913 1.00 12.50 ? 36 LEU A CG 1 ATOM 249 C CD1 . LEU A 1 36 ? 20.259 83.001 18.942 1.00 12.50 ? 36 LEU A CD1 1 ATOM 250 C CD2 . LEU A 1 36 ? 20.618 81.749 21.073 1.00 12.50 ? 36 LEU A CD2 1 ATOM 251 N N . GLN A 1 37 ? 15.979 82.439 22.680 1.00 20.95 ? 37 GLN A N 1 ATOM 252 C CA . GLN A 1 37 ? 14.739 83.036 23.172 1.00 20.95 ? 37 GLN A CA 1 ATOM 253 C C . GLN A 1 37 ? 14.782 84.516 22.883 1.00 20.95 ? 37 GLN A C 1 ATOM 254 O O . GLN A 1 37 ? 15.788 85.164 23.161 1.00 20.95 ? 37 GLN A O 1 ATOM 255 C CB . GLN A 1 37 ? 14.593 82.801 24.670 1.00 19.77 ? 37 GLN A CB 1 ATOM 256 C CG . GLN A 1 37 ? 13.433 83.542 25.270 1.00 19.77 ? 37 GLN A CG 1 ATOM 257 C CD . GLN A 1 37 ? 13.119 83.085 26.669 1.00 31.37 ? 37 GLN A CD 1 ATOM 258 O OE1 . GLN A 1 37 ? 12.399 83.755 27.413 1.00 24.43 ? 37 GLN A OE1 1 ATOM 259 N NE2 . GLN A 1 37 ? 13.643 81.929 27.034 1.00 23.20 ? 37 GLN A NE2 1 ATOM 260 N N . PHE A 1 38 ? 13.696 85.063 22.346 1.00 13.02 ? 38 PHE A N 1 ATOM 261 C CA . PHE A 1 38 ? 13.692 86.474 21.990 1.00 13.02 ? 38 PHE A CA 1 ATOM 262 C C . PHE A 1 38 ? 12.715 87.357 22.757 1.00 13.02 ? 38 PHE A C 1 ATOM 263 O O . PHE A 1 38 ? 12.799 88.586 22.695 1.00 13.02 ? 38 PHE A O 1 ATOM 264 C CB . PHE A 1 38 ? 13.467 86.621 20.480 1.00 16.76 ? 38 PHE A CB 1 ATOM 265 C CG . PHE A 1 38 ? 12.068 86.274 20.024 1.00 16.76 ? 38 PHE A CG 1 ATOM 266 C CD1 . PHE A 1 38 ? 11.046 87.214 20.085 1.00 16.76 ? 38 PHE A CD1 1 ATOM 267 C CD2 . PHE A 1 38 ? 11.775 85.008 19.536 1.00 16.76 ? 38 PHE A CD2 1 ATOM 268 C CE1 . PHE A 1 38 ? 9.766 86.899 19.671 1.00 16.76 ? 38 PHE A CE1 1 ATOM 269 C CE2 . PHE A 1 38 ? 10.496 84.690 19.124 1.00 16.76 ? 38 PHE A CE2 1 ATOM 270 C CZ . PHE A 1 38 ? 9.488 85.637 19.191 1.00 16.76 ? 38 PHE A CZ 1 ATOM 271 N N . PHE A 1 39 ? 11.788 86.754 23.486 1.00 19.91 ? 39 PHE A N 1 ATOM 272 C CA . PHE A 1 39 ? 10.855 87.565 24.244 1.00 19.91 ? 39 PHE A CA 1 ATOM 273 C C . PHE A 1 39 ? 10.350 86.823 25.481 1.00 19.91 ? 39 PHE A C 1 ATOM 274 O O . PHE A 1 39 ? 10.643 85.638 25.663 1.00 19.91 ? 39 PHE A O 1 ATOM 275 C CB . PHE A 1 39 ? 9.713 88.014 23.323 1.00 12.15 ? 39 PHE A CB 1 ATOM 276 C CG . PHE A 1 39 ? 8.398 87.373 23.612 1.00 12.15 ? 39 PHE A CG 1 ATOM 277 C CD1 . PHE A 1 39 ? 8.111 86.095 23.148 1.00 12.15 ? 39 PHE A CD1 1 ATOM 278 C CD2 . PHE A 1 39 ? 7.436 88.047 24.373 1.00 12.15 ? 39 PHE A CD2 1 ATOM 279 C CE1 . PHE A 1 39 ? 6.885 85.489 23.437 1.00 12.15 ? 39 PHE A CE1 1 ATOM 280 C CE2 . PHE A 1 39 ? 6.195 87.447 24.673 1.00 13.22 ? 39 PHE A CE2 1 ATOM 281 C CZ . PHE A 1 39 ? 5.923 86.170 24.205 1.00 12.15 ? 39 PHE A CZ 1 ATOM 282 N N . ARG A 1 40 ? 9.638 87.527 26.356 1.00 16.58 ? 40 ARG A N 1 ATOM 283 C CA . ARG A 1 40 ? 9.097 86.899 27.558 1.00 16.58 ? 40 ARG A CA 1 ATOM 284 C C . ARG A 1 40 ? 7.991 87.772 28.100 1.00 16.58 ? 40 ARG A C 1 ATOM 285 O O . ARG A 1 40 ? 7.998 88.969 27.886 1.00 16.58 ? 40 ARG A O 1 ATOM 286 C CB . ARG A 1 40 ? 10.173 86.730 28.625 1.00 43.54 ? 40 ARG A CB 1 ATOM 287 C CG . ARG A 1 40 ? 10.607 88.024 29.257 1.00 49.95 ? 40 ARG A CG 1 ATOM 288 C CD . ARG A 1 40 ? 11.625 87.793 30.350 1.00 56.78 ? 40 ARG A CD 1 ATOM 289 N NE . ARG A 1 40 ? 11.989 89.045 31.002 1.00 66.31 ? 40 ARG A NE 1 ATOM 290 C CZ . ARG A 1 40 ? 12.872 89.143 31.988 1.00 78.16 ? 40 ARG A CZ 1 ATOM 291 N NH1 . ARG A 1 40 ? 13.484 88.056 32.440 1.00 77.27 ? 40 ARG A NH1 1 ATOM 292 N NH2 . ARG A 1 40 ? 13.146 90.329 32.517 1.00 81.50 ? 40 ARG A NH2 1 ATOM 293 N N . TYR A 1 41 ? 7.040 87.173 28.802 1.00 17.11 ? 41 TYR A N 1 ATOM 294 C CA . TYR A 1 41 ? 5.924 87.914 29.357 1.00 17.11 ? 41 TYR A CA 1 ATOM 295 C C . TYR A 1 41 ? 5.336 87.160 30.540 1.00 17.11 ? 41 TYR A C 1 ATOM 296 O O . TYR A 1 41 ? 5.138 85.960 30.459 1.00 17.11 ? 41 TYR A O 1 ATOM 297 C CB . TYR A 1 41 ? 4.857 88.109 28.277 1.00 10.67 ? 41 TYR A CB 1 ATOM 298 C CG . TYR A 1 41 ? 3.549 88.680 28.775 1.00 10.67 ? 41 TYR A CG 1 ATOM 299 C CD1 . TYR A 1 41 ? 2.608 87.876 29.415 1.00 10.67 ? 41 TYR A CD1 1 ATOM 300 C CD2 . TYR A 1 41 ? 3.277 90.033 28.649 1.00 10.67 ? 41 TYR A CD2 1 ATOM 301 C CE1 . TYR A 1 41 ? 1.438 88.408 29.923 1.00 10.67 ? 41 TYR A CE1 1 ATOM 302 C CE2 . TYR A 1 41 ? 2.112 90.579 29.149 1.00 10.67 ? 41 TYR A CE2 1 ATOM 303 C CZ . TYR A 1 41 ? 1.196 89.769 29.788 1.00 10.67 ? 41 TYR A CZ 1 ATOM 304 O OH . TYR A 1 41 ? 0.050 90.340 30.309 1.00 10.67 ? 41 TYR A OH 1 ATOM 305 N N . ASN A 1 42 ? 5.065 87.844 31.643 1.00 6.62 ? 42 ASN A N 1 ATOM 306 C CA . ASN A 1 42 ? 4.467 87.172 32.779 1.00 6.62 ? 42 ASN A CA 1 ATOM 307 C C . ASN A 1 42 ? 3.338 88.029 33.368 1.00 6.62 ? 42 ASN A C 1 ATOM 308 O O . ASN A 1 42 ? 3.257 89.221 33.105 1.00 6.62 ? 42 ASN A O 1 ATOM 309 C CB . ASN A 1 42 ? 5.530 86.871 33.825 1.00 22.06 ? 42 ASN A CB 1 ATOM 310 C CG . ASN A 1 42 ? 6.031 88.102 34.506 1.00 25.92 ? 42 ASN A CG 1 ATOM 311 O OD1 . ASN A 1 42 ? 5.260 88.838 35.110 1.00 26.24 ? 42 ASN A OD1 1 ATOM 312 N ND2 . ASN A 1 42 ? 7.332 88.336 34.424 1.00 25.21 ? 42 ASN A ND2 1 ATOM 313 N N . SER A 1 43 ? 2.466 87.421 34.166 1.00 12.32 ? 43 SER A N 1 ATOM 314 C CA . SER A 1 43 ? 1.333 88.131 34.751 1.00 12.32 ? 43 SER A CA 1 ATOM 315 C C . SER A 1 43 ? 1.661 89.160 35.843 1.00 16.82 ? 43 SER A C 1 ATOM 316 O O . SER A 1 43 ? 0.759 89.810 36.372 1.00 14.96 ? 43 SER A O 1 ATOM 317 C CB . SER A 1 43 ? 0.319 87.114 35.286 1.00 13.80 ? 43 SER A CB 1 ATOM 318 O OG . SER A 1 43 ? 0.891 86.285 36.281 1.00 13.80 ? 43 SER A OG 1 ATOM 319 N N . LYS A 1 44 ? 2.936 89.322 36.185 1.00 21.48 ? 44 LYS A N 1 ATOM 320 C CA . LYS A 1 44 ? 3.303 90.295 37.213 1.00 32.68 ? 44 LYS A CA 1 ATOM 321 C C . LYS A 1 44 ? 3.580 91.675 36.605 1.00 31.17 ? 44 LYS A C 1 ATOM 322 O O . LYS A 1 44 ? 2.897 92.654 36.922 1.00 32.92 ? 44 LYS A O 1 ATOM 323 C CB . LYS A 1 44 ? 4.523 89.819 38.000 1.00 82.90 ? 44 LYS A CB 1 ATOM 324 C CG . LYS A 1 44 ? 4.798 90.646 39.244 1.00 98.12 ? 44 LYS A CG 1 ATOM 325 C CD . LYS A 1 44 ? 6.051 90.174 39.964 1.00 107.13 ? 44 LYS A CD 1 ATOM 326 C CE . LYS A 1 44 ? 6.336 91.022 41.197 1.00 115.49 ? 44 LYS A CE 1 ATOM 327 N NZ . LYS A 1 44 ? 7.582 90.591 41.895 1.00 113.45 ? 44 LYS A NZ 1 ATOM 328 N N . ASP A 1 45 ? 4.574 91.755 35.727 1.00 22.46 ? 45 ASP A N 1 ATOM 329 C CA . ASP A 1 45 ? 4.908 93.021 35.090 1.00 24.13 ? 45 ASP A CA 1 ATOM 330 C C . ASP A 1 45 ? 4.004 93.250 33.878 1.00 28.81 ? 45 ASP A C 1 ATOM 331 O O . ASP A 1 45 ? 3.912 94.356 33.355 1.00 21.32 ? 45 ASP A O 1 ATOM 332 C CB . ASP A 1 45 ? 6.381 93.025 34.666 1.00 108.17 ? 45 ASP A CB 1 ATOM 333 C CG . ASP A 1 45 ? 7.333 92.845 35.844 1.00 121.42 ? 45 ASP A CG 1 ATOM 334 O OD1 . ASP A 1 45 ? 7.284 93.667 36.784 1.00 118.24 ? 45 ASP A OD1 1 ATOM 335 O OD2 . ASP A 1 45 ? 8.131 91.882 35.830 1.00 129.71 ? 45 ASP A OD2 1 ATOM 336 N N . ARG A 1 46 ? 3.335 92.189 33.443 1.00 24.55 ? 46 ARG A N 1 ATOM 337 C CA . ARG A 1 46 ? 2.425 92.228 32.305 1.00 20.68 ? 46 ARG A CA 1 ATOM 338 C C . ARG A 1 46 ? 2.955 93.011 31.116 1.00 23.65 ? 46 ARG A C 1 ATOM 339 O O . ARG A 1 46 ? 2.201 93.727 30.474 1.00 21.76 ? 46 ARG A O 1 ATOM 340 C CB . ARG A 1 46 ? 1.084 92.824 32.725 1.00 25.59 ? 46 ARG A CB 1 ATOM 341 C CG . ARG A 1 46 ? 0.572 92.339 34.071 1.00 40.22 ? 46 ARG A CG 1 ATOM 342 C CD . ARG A 1 46 ? -0.816 92.874 34.346 1.00 41.32 ? 46 ARG A CD 1 ATOM 343 N NE . ARG A 1 46 ? -1.780 92.270 33.444 1.00 42.18 ? 46 ARG A NE 1 ATOM 344 C CZ . ARG A 1 46 ? -2.270 91.047 33.595 1.00 50.86 ? 46 ARG A CZ 1 ATOM 345 N NH1 . ARG A 1 46 ? -1.888 90.299 34.625 1.00 28.30 ? 46 ARG A NH1 1 ATOM 346 N NH2 . ARG A 1 46 ? -3.133 90.567 32.708 1.00 57.89 ? 46 ARG A NH2 1 ATOM 347 N N . LYS A 1 47 ? 4.241 92.876 30.807 1.00 23.76 ? 47 LYS A N 1 ATOM 348 C CA . LYS A 1 47 ? 4.809 93.600 29.673 1.00 26.70 ? 47 LYS A CA 1 ATOM 349 C C . LYS A 1 47 ? 5.710 92.748 28.773 1.00 28.10 ? 47 LYS A C 1 ATOM 350 O O . LYS A 1 47 ? 6.701 92.189 29.232 1.00 24.05 ? 47 LYS A O 1 ATOM 351 C CB . LYS A 1 47 ? 5.597 94.812 30.175 1.00 67.79 ? 47 LYS A CB 1 ATOM 352 C CG . LYS A 1 47 ? 4.749 95.824 30.920 1.00 72.67 ? 47 LYS A CG 1 ATOM 353 C CD . LYS A 1 47 ? 3.578 96.308 30.058 1.00 86.25 ? 47 LYS A CD 1 ATOM 354 C CE . LYS A 1 47 ? 2.624 97.208 30.836 1.00 90.86 ? 47 LYS A CE 1 ATOM 355 N NZ . LYS A 1 47 ? 1.435 97.567 30.020 1.00 87.11 ? 47 LYS A NZ 1 ATOM 356 N N . SER A 1 48 ? 5.367 92.643 27.493 1.00 20.09 ? 48 SER A N 1 ATOM 357 C CA . SER A 1 48 ? 6.194 91.879 26.567 1.00 23.11 ? 48 SER A CA 1 ATOM 358 C C . SER A 1 48 ? 7.569 92.526 26.528 1.00 25.96 ? 48 SER A C 1 ATOM 359 O O . SER A 1 48 ? 7.675 93.731 26.337 1.00 25.89 ? 48 SER A O 1 ATOM 360 C CB . SER A 1 48 ? 5.599 91.894 25.161 1.00 49.70 ? 48 SER A CB 1 ATOM 361 O OG . SER A 1 48 ? 4.374 91.191 25.122 1.00 58.16 ? 48 SER A OG 1 ATOM 362 N N . GLN A 1 49 ? 8.616 91.728 26.701 1.00 16.83 ? 49 GLN A N 1 ATOM 363 C CA . GLN A 1 49 ? 9.975 92.243 26.686 1.00 20.46 ? 49 GLN A CA 1 ATOM 364 C C . GLN A 1 49 ? 10.945 91.445 25.816 1.00 20.44 ? 49 GLN A C 1 ATOM 365 O O . GLN A 1 49 ? 11.083 90.233 25.970 1.00 18.52 ? 49 GLN A O 1 ATOM 366 C CB . GLN A 1 49 ? 10.517 92.303 28.114 1.00 63.09 ? 49 GLN A CB 1 ATOM 367 C CG . GLN A 1 49 ? 9.706 93.187 29.034 1.00 74.60 ? 49 GLN A CG 1 ATOM 368 C CD . GLN A 1 49 ? 10.263 93.239 30.441 1.00 82.31 ? 49 GLN A CD 1 ATOM 369 O OE1 . GLN A 1 49 ? 10.357 92.218 31.124 1.00 88.12 ? 49 GLN A OE1 1 ATOM 370 N NE2 . GLN A 1 49 ? 10.636 94.433 30.884 1.00 84.98 ? 49 GLN A NE2 1 ATOM 371 N N . PRO A 1 50 ? 11.635 92.122 24.885 1.00 11.72 ? 50 PRO A N 1 ATOM 372 C CA . PRO A 1 50 ? 12.598 91.454 24.006 1.00 11.72 ? 50 PRO A CA 1 ATOM 373 C C . PRO A 1 50 ? 13.725 90.903 24.858 1.00 11.72 ? 50 PRO A C 1 ATOM 374 O O . PRO A 1 50 ? 13.894 91.321 26.000 1.00 11.72 ? 50 PRO A O 1 ATOM 375 C CB . PRO A 1 50 ? 13.079 92.583 23.108 1.00 17.36 ? 50 PRO A CB 1 ATOM 376 C CG . PRO A 1 50 ? 12.992 93.768 24.008 1.00 21.73 ? 50 PRO A CG 1 ATOM 377 C CD . PRO A 1 50 ? 11.654 93.576 24.659 1.00 18.86 ? 50 PRO A CD 1 ATOM 378 N N . MET A 1 51 ? 14.508 89.983 24.315 1.00 20.39 ? 51 MET A N 1 ATOM 379 C CA . MET A 1 51 ? 15.604 89.411 25.075 1.00 20.39 ? 51 MET A CA 1 ATOM 380 C C . MET A 1 51 ? 16.828 89.155 24.237 1.00 20.39 ? 51 MET A C 1 ATOM 381 O O . MET A 1 51 ? 16.768 89.175 23.012 1.00 20.39 ? 51 MET A O 1 ATOM 382 C CB . MET A 1 51 ? 15.156 88.114 25.727 1.00 22.95 ? 51 MET A CB 1 ATOM 383 C CG . MET A 1 51 ? 14.324 88.351 26.960 1.00 27.32 ? 51 MET A CG 1 ATOM 384 S SD . MET A 1 51 ? 13.719 86.853 27.697 1.00 42.68 ? 51 MET A SD 1 ATOM 385 C CE . MET A 1 51 ? 15.247 85.928 27.922 1.00 41.89 ? 51 MET A CE 1 ATOM 386 N N . GLY A 1 52 ? 17.948 88.914 24.903 1.00 20.31 ? 52 GLY A N 1 ATOM 387 C CA . GLY A 1 52 ? 19.174 88.633 24.187 1.00 20.31 ? 52 GLY A CA 1 ATOM 388 C C . GLY A 1 52 ? 19.474 89.748 23.229 1.00 20.31 ? 52 GLY A C 1 ATOM 389 O O . GLY A 1 52 ? 19.135 90.900 23.497 1.00 21.87 ? 52 GLY A O 1 ATOM 390 N N . LEU A 1 53 ? 20.096 89.402 22.107 1.00 28.81 ? 53 LEU A N 1 ATOM 391 C CA . LEU A 1 53 ? 20.463 90.375 21.086 1.00 28.81 ? 53 LEU A CA 1 ATOM 392 C C . LEU A 1 53 ? 19.268 91.110 20.508 1.00 36.16 ? 53 LEU A C 1 ATOM 393 O O . LEU A 1 53 ? 19.420 92.145 19.877 1.00 33.11 ? 53 LEU A O 1 ATOM 394 C CB . LEU A 1 53 ? 21.199 89.681 19.956 1.00 9.35 ? 53 LEU A CB 1 ATOM 395 C CG . LEU A 1 53 ? 22.438 88.893 20.355 1.00 14.75 ? 53 LEU A CG 1 ATOM 396 C CD1 . LEU A 1 53 ? 22.832 87.946 19.246 1.00 9.65 ? 53 LEU A CD1 1 ATOM 397 C CD2 . LEU A 1 53 ? 23.549 89.850 20.648 1.00 13.63 ? 53 LEU A CD2 1 ATOM 398 N N . TRP A 1 54 ? 18.075 90.578 20.703 1.00 27.48 ? 54 TRP A N 1 ATOM 399 C CA . TRP A 1 54 ? 16.905 91.242 20.168 1.00 25.26 ? 54 TRP A CA 1 ATOM 400 C C . TRP A 1 54 ? 16.599 92.471 20.985 1.00 24.88 ? 54 TRP A C 1 ATOM 401 O O . TRP A 1 54 ? 15.695 93.234 20.653 1.00 27.26 ? 54 TRP A O 1 ATOM 402 C CB . TRP A 1 54 ? 15.709 90.288 20.150 1.00 13.11 ? 54 TRP A CB 1 ATOM 403 C CG . TRP A 1 54 ? 15.709 89.408 18.941 1.00 13.11 ? 54 TRP A CG 1 ATOM 404 C CD1 . TRP A 1 54 ? 15.298 89.748 17.695 1.00 13.11 ? 54 TRP A CD1 1 ATOM 405 C CD2 . TRP A 1 54 ? 16.207 88.065 18.847 1.00 13.11 ? 54 TRP A CD2 1 ATOM 406 N NE1 . TRP A 1 54 ? 15.506 88.713 16.824 1.00 13.11 ? 54 TRP A NE1 1 ATOM 407 C CE2 . TRP A 1 54 ? 16.063 87.663 17.504 1.00 13.11 ? 54 TRP A CE2 1 ATOM 408 C CE3 . TRP A 1 54 ? 16.764 87.164 19.768 1.00 13.11 ? 54 TRP A CE3 1 ATOM 409 C CZ2 . TRP A 1 54 ? 16.456 86.391 17.050 1.00 13.11 ? 54 TRP A CZ2 1 ATOM 410 C CZ3 . TRP A 1 54 ? 17.158 85.902 19.320 1.00 13.11 ? 54 TRP A CZ3 1 ATOM 411 C CH2 . TRP A 1 54 ? 17.000 85.530 17.972 1.00 13.11 ? 54 TRP A CH2 1 ATOM 412 N N . ARG A 1 55 ? 17.356 92.663 22.058 1.00 9.81 ? 55 ARG A N 1 ATOM 413 C CA . ARG A 1 55 ? 17.159 93.822 22.916 1.00 14.24 ? 55 ARG A CA 1 ATOM 414 C C . ARG A 1 55 ? 17.672 95.050 22.197 1.00 15.14 ? 55 ARG A C 1 ATOM 415 O O . ARG A 1 55 ? 17.265 96.171 22.488 1.00 18.32 ? 55 ARG A O 1 ATOM 416 C CB . ARG A 1 55 ? 17.919 93.654 24.227 1.00 51.22 ? 55 ARG A CB 1 ATOM 417 C CG . ARG A 1 55 ? 17.184 92.877 25.286 1.00 49.81 ? 55 ARG A CG 1 ATOM 418 C CD . ARG A 1 55 ? 18.054 92.708 26.513 1.00 42.62 ? 55 ARG A CD 1 ATOM 419 N NE . ARG A 1 55 ? 19.190 91.822 26.261 1.00 50.79 ? 55 ARG A NE 1 ATOM 420 C CZ . ARG A 1 55 ? 20.159 91.576 27.139 1.00 58.84 ? 55 ARG A CZ 1 ATOM 421 N NH1 . ARG A 1 55 ? 20.140 92.151 28.334 1.00 58.04 ? 55 ARG A NH1 1 ATOM 422 N NH2 . ARG A 1 55 ? 21.148 90.749 26.827 1.00 58.87 ? 55 ARG A NH2 1 ATOM 423 N N . GLN A 1 56 ? 18.562 94.807 21.241 1.00 25.21 ? 56 GLN A N 1 ATOM 424 C CA . GLN A 1 56 ? 19.194 95.851 20.452 1.00 37.00 ? 56 GLN A CA 1 ATOM 425 C C . GLN A 1 56 ? 18.592 95.984 19.060 1.00 37.79 ? 56 GLN A C 1 ATOM 426 O O . GLN A 1 56 ? 18.969 96.870 18.304 1.00 41.95 ? 56 GLN A O 1 ATOM 427 C CB . GLN A 1 56 ? 20.688 95.559 20.342 1.00 75.31 ? 56 GLN A CB 1 ATOM 428 C CG . GLN A 1 56 ? 21.382 95.392 21.687 1.00 91.48 ? 56 GLN A CG 1 ATOM 429 C CD . GLN A 1 56 ? 22.779 94.810 21.555 1.00 104.34 ? 56 GLN A CD 1 ATOM 430 O OE1 . GLN A 1 56 ? 22.946 93.647 21.190 1.00 100.28 ? 56 GLN A OE1 1 ATOM 431 N NE2 . GLN A 1 56 ? 23.791 95.622 21.846 1.00 110.58 ? 56 GLN A NE2 1 ATOM 432 N N . VAL A 1 57 ? 17.660 95.104 18.715 1.00 35.56 ? 57 VAL A N 1 ATOM 433 C CA . VAL A 1 57 ? 17.018 95.159 17.401 1.00 34.30 ? 57 VAL A CA 1 ATOM 434 C C . VAL A 1 57 ? 15.828 96.115 17.398 1.00 41.70 ? 57 VAL A C 1 ATOM 435 O O . VAL A 1 57 ? 14.845 95.913 18.112 1.00 41.31 ? 57 VAL A O 1 ATOM 436 C CB . VAL A 1 57 ? 16.547 93.768 16.955 1.00 19.04 ? 57 VAL A CB 1 ATOM 437 C CG1 . VAL A 1 57 ? 15.660 93.895 15.728 1.00 9.65 ? 57 VAL A CG1 1 ATOM 438 C CG2 . VAL A 1 57 ? 17.756 92.887 16.660 1.00 12.15 ? 57 VAL A CG2 1 ATOM 439 N N . GLU A 1 58 ? 15.915 97.150 16.573 1.00 46.52 ? 58 GLU A N 1 ATOM 440 C CA . GLU A 1 58 ? 14.863 98.154 16.511 1.00 44.59 ? 58 GLU A CA 1 ATOM 441 C C . GLU A 1 58 ? 13.913 98.020 15.332 1.00 37.60 ? 58 GLU A C 1 ATOM 442 O O . GLU A 1 58 ? 14.335 97.784 14.198 1.00 36.16 ? 58 GLU A O 1 ATOM 443 C CB . GLU A 1 58 ? 15.490 99.553 16.513 1.00 78.51 ? 58 GLU A CB 1 ATOM 444 C CG . GLU A 1 58 ? 16.347 99.837 17.749 1.00 96.07 ? 58 GLU A CG 1 ATOM 445 C CD . GLU A 1 58 ? 16.994 101.215 17.736 1.00 107.57 ? 58 GLU A CD 1 ATOM 446 O OE1 . GLU A 1 58 ? 16.257 102.225 17.724 1.00 116.69 ? 58 GLU A OE1 1 ATOM 447 O OE2 . GLU A 1 58 ? 18.243 101.286 17.742 1.00 108.09 ? 58 GLU A OE2 1 ATOM 448 N N . GLY A 1 59 ? 12.622 98.157 15.618 1.00 46.35 ? 59 GLY A N 1 ATOM 449 C CA . GLY A 1 59 ? 11.618 98.086 14.575 1.00 56.45 ? 59 GLY A CA 1 ATOM 450 C C . GLY A 1 59 ? 11.131 96.724 14.119 1.00 58.11 ? 59 GLY A C 1 ATOM 451 O O . GLY A 1 59 ? 10.598 96.603 13.016 1.00 54.46 ? 59 GLY A O 1 ATOM 452 N N . MET A 1 60 ? 11.294 95.699 14.948 1.00 34.92 ? 60 MET A N 1 ATOM 453 C CA . MET A 1 60 ? 10.836 94.364 14.574 1.00 27.69 ? 60 MET A CA 1 ATOM 454 C C . MET A 1 60 ? 9.478 94.061 15.179 1.00 27.92 ? 60 MET A C 1 ATOM 455 O O . MET A 1 60 ? 8.706 93.291 14.624 1.00 23.04 ? 60 MET A O 1 ATOM 456 C CB . MET A 1 60 ? 11.826 93.304 15.036 1.00 53.05 ? 60 MET A CB 1 ATOM 457 C CG . MET A 1 60 ? 11.340 91.888 14.819 1.00 46.29 ? 60 MET A CG 1 ATOM 458 S SD . MET A 1 60 ? 12.366 90.707 15.674 1.00 42.41 ? 60 MET A SD 1 ATOM 459 C CE . MET A 1 60 ? 13.547 90.342 14.418 1.00 57.49 ? 60 MET A CE 1 ATOM 460 N N . GLU A 1 61 ? 9.198 94.674 16.323 1.00 26.59 ? 61 GLU A N 1 ATOM 461 C CA . GLU A 1 61 ? 7.935 94.470 17.015 1.00 24.26 ? 61 GLU A CA 1 ATOM 462 C C . GLU A 1 61 ? 7.643 95.670 17.926 1.00 29.03 ? 61 GLU A C 1 ATOM 463 O O . GLU A 1 61 ? 8.539 96.170 18.608 1.00 34.03 ? 61 GLU A O 1 ATOM 464 C CB . GLU A 1 61 ? 8.013 93.177 17.843 1.00 35.15 ? 61 GLU A CB 1 ATOM 465 C CG . GLU A 1 61 ? 6.682 92.673 18.386 1.00 35.70 ? 61 GLU A CG 1 ATOM 466 C CD . GLU A 1 61 ? 5.680 92.376 17.290 1.00 38.99 ? 61 GLU A CD 1 ATOM 467 O OE1 . GLU A 1 61 ? 5.949 91.482 16.463 1.00 35.29 ? 61 GLU A OE1 1 ATOM 468 O OE2 . GLU A 1 61 ? 4.623 93.043 17.257 1.00 48.82 ? 61 GLU A OE2 1 ATOM 469 N N . ASP A 1 62 ? 6.401 96.147 17.922 1.00 28.64 ? 62 ASP A N 1 ATOM 470 C CA . ASP A 1 62 ? 6.029 97.271 18.773 1.00 31.96 ? 62 ASP A CA 1 ATOM 471 C C . ASP A 1 62 ? 5.645 96.686 20.123 1.00 31.55 ? 62 ASP A C 1 ATOM 472 O O . ASP A 1 62 ? 4.481 96.713 20.513 1.00 25.83 ? 62 ASP A O 1 ATOM 473 C CB . ASP A 1 62 ? 4.840 98.025 18.179 1.00 53.79 ? 62 ASP A CB 1 ATOM 474 C CG . ASP A 1 62 ? 4.434 99.227 19.015 1.00 57.49 ? 62 ASP A CG 1 ATOM 475 O OD1 . ASP A 1 62 ? 4.284 99.081 20.241 1.00 52.43 ? 62 ASP A OD1 1 ATOM 476 O OD2 . ASP A 1 62 ? 4.255 100.324 18.452 1.00 64.59 ? 62 ASP A OD2 1 ATOM 477 N N . TRP A 1 63 ? 6.631 96.160 20.838 1.00 27.30 ? 63 TRP A N 1 ATOM 478 C CA . TRP A 1 63 ? 6.399 95.529 22.132 1.00 24.47 ? 63 TRP A CA 1 ATOM 479 C C . TRP A 1 63 ? 5.287 96.124 22.994 1.00 26.07 ? 63 TRP A C 1 ATOM 480 O O . TRP A 1 63 ? 4.517 95.378 23.595 1.00 22.15 ? 63 TRP A O 1 ATOM 481 C CB . TRP A 1 63 ? 7.706 95.476 22.919 1.00 20.05 ? 63 TRP A CB 1 ATOM 482 C CG . TRP A 1 63 ? 8.806 94.786 22.175 1.00 15.21 ? 63 TRP A CG 1 ATOM 483 C CD1 . TRP A 1 63 ? 9.977 95.336 21.760 1.00 18.72 ? 63 TRP A CD1 1 ATOM 484 C CD2 . TRP A 1 63 ? 8.825 93.422 21.728 1.00 17.86 ? 63 TRP A CD2 1 ATOM 485 N NE1 . TRP A 1 63 ? 10.727 94.407 21.080 1.00 19.44 ? 63 TRP A NE1 1 ATOM 486 C CE2 . TRP A 1 63 ? 10.040 93.223 21.046 1.00 18.64 ? 63 TRP A CE2 1 ATOM 487 C CE3 . TRP A 1 63 ? 7.930 92.346 21.841 1.00 21.26 ? 63 TRP A CE3 1 ATOM 488 C CZ2 . TRP A 1 63 ? 10.387 91.995 20.477 1.00 22.77 ? 63 TRP A CZ2 1 ATOM 489 C CZ3 . TRP A 1 63 ? 8.276 91.125 21.278 1.00 19.18 ? 63 TRP A CZ3 1 ATOM 490 C CH2 . TRP A 1 63 ? 9.495 90.962 20.604 1.00 21.36 ? 63 TRP A CH2 1 ATOM 491 N N . LYS A 1 64 ? 5.186 97.449 23.056 1.00 45.07 ? 64 LYS A N 1 ATOM 492 C CA . LYS A 1 64 ? 4.145 98.087 23.868 1.00 47.23 ? 64 LYS A CA 1 ATOM 493 C C . LYS A 1 64 ? 2.752 97.555 23.533 1.00 42.71 ? 64 LYS A C 1 ATOM 494 O O . LYS A 1 64 ? 1.900 97.392 24.416 1.00 42.21 ? 64 LYS A O 1 ATOM 495 C CB . LYS A 1 64 ? 4.167 99.610 23.686 1.00 97.19 ? 64 LYS A CB 1 ATOM 496 C CG . LYS A 1 64 ? 5.292 100.310 24.431 1.00 112.95 ? 64 LYS A CG 1 ATOM 497 C CD . LYS A 1 64 ? 5.193 101.825 24.306 1.00 125.95 ? 64 LYS A CD 1 ATOM 498 C CE . LYS A 1 64 ? 6.260 102.523 25.144 1.00 130.10 ? 64 LYS A CE 1 ATOM 499 N NZ . LYS A 1 64 ? 7.641 102.113 24.758 1.00 136.92 ? 64 LYS A NZ 1 ATOM 500 N N . GLN A 1 65 ? 2.532 97.287 22.249 1.00 47.72 ? 65 GLN A N 1 ATOM 501 C CA . GLN A 1 65 ? 1.253 96.775 21.779 1.00 50.31 ? 65 GLN A CA 1 ATOM 502 C C . GLN A 1 65 ? 1.181 95.273 22.010 1.00 45.51 ? 65 GLN A C 1 ATOM 503 O O . GLN A 1 65 ? 0.146 94.756 22.443 1.00 45.08 ? 65 GLN A O 1 ATOM 504 C CB . GLN A 1 65 ? 1.075 97.097 20.288 1.00 83.54 ? 65 GLN A CB 1 ATOM 505 C CG . GLN A 1 65 ? -0.230 96.605 19.664 1.00 92.18 ? 65 GLN A CG 1 ATOM 506 C CD . GLN A 1 65 ? -1.467 97.076 20.412 1.00 103.57 ? 65 GLN A CD 1 ATOM 507 O OE1 . GLN A 1 65 ? -1.587 98.250 20.770 1.00 105.42 ? 65 GLN A OE1 1 ATOM 508 N NE2 . GLN A 1 65 ? -2.402 96.159 20.641 1.00 90.11 ? 65 GLN A NE2 1 ATOM 509 N N . ASP A 1 66 ? 2.284 94.580 21.732 1.00 22.80 ? 66 ASP A N 1 ATOM 510 C CA . ASP A 1 66 ? 2.329 93.140 21.916 1.00 21.43 ? 66 ASP A CA 1 ATOM 511 C C . ASP A 1 66 ? 1.954 92.810 23.349 1.00 23.03 ? 66 ASP A C 1 ATOM 512 O O . ASP A 1 66 ? 1.450 91.726 23.630 1.00 17.18 ? 66 ASP A O 1 ATOM 513 C CB . ASP A 1 66 ? 3.722 92.593 21.626 1.00 19.79 ? 66 ASP A CB 1 ATOM 514 C CG . ASP A 1 66 ? 3.739 91.080 21.522 1.00 28.59 ? 66 ASP A CG 1 ATOM 515 O OD1 . ASP A 1 66 ? 3.114 90.549 20.586 1.00 27.26 ? 66 ASP A OD1 1 ATOM 516 O OD2 . ASP A 1 66 ? 4.365 90.411 22.367 1.00 22.07 ? 66 ASP A OD2 1 ATOM 517 N N . SER A 1 67 ? 2.201 93.752 24.255 1.00 12.80 ? 67 SER A N 1 ATOM 518 C CA . SER A 1 67 ? 1.883 93.545 25.661 1.00 12.80 ? 67 SER A CA 1 ATOM 519 C C . SER A 1 67 ? 0.381 93.415 25.802 1.00 15.92 ? 67 SER A C 1 ATOM 520 O O . SER A 1 67 ? -0.124 92.648 26.618 1.00 12.80 ? 67 SER A O 1 ATOM 521 C CB . SER A 1 67 ? 2.383 94.720 26.497 1.00 27.07 ? 67 SER A CB 1 ATOM 522 O OG . SER A 1 67 ? 3.770 94.919 26.310 1.00 28.89 ? 67 SER A OG 1 ATOM 523 N N . GLN A 1 68 ? -0.329 94.175 24.987 1.00 19.36 ? 68 GLN A N 1 ATOM 524 C CA . GLN A 1 68 ? -1.769 94.158 25.002 1.00 16.56 ? 68 GLN A CA 1 ATOM 525 C C . GLN A 1 68 ? -2.261 92.855 24.400 1.00 15.35 ? 68 GLN A C 1 ATOM 526 O O . GLN A 1 68 ? -3.286 92.316 24.806 1.00 16.68 ? 68 GLN A O 1 ATOM 527 C CB . GLN A 1 68 ? -2.294 95.354 24.217 1.00 33.52 ? 68 GLN A CB 1 ATOM 528 C CG . GLN A 1 68 ? -2.109 96.671 24.944 1.00 34.73 ? 68 GLN A CG 1 ATOM 529 C CD . GLN A 1 68 ? -2.733 96.638 26.326 1.00 33.69 ? 68 GLN A CD 1 ATOM 530 O OE1 . GLN A 1 68 ? -3.934 96.393 26.472 1.00 43.84 ? 68 GLN A OE1 1 ATOM 531 N NE2 . GLN A 1 68 ? -1.918 96.877 27.351 1.00 33.33 ? 68 GLN A NE2 1 ATOM 532 N N . LEU A 1 69 ? -1.519 92.349 23.423 1.00 26.14 ? 69 LEU A N 1 ATOM 533 C CA . LEU A 1 69 ? -1.873 91.095 22.775 1.00 29.84 ? 69 LEU A CA 1 ATOM 534 C C . LEU A 1 69 ? -1.761 89.982 23.818 1.00 27.55 ? 69 LEU A C 1 ATOM 535 O O . LEU A 1 69 ? -2.696 89.220 24.046 1.00 26.14 ? 69 LEU A O 1 ATOM 536 C CB . LEU A 1 69 ? -0.924 90.840 21.602 1.00 18.82 ? 69 LEU A CB 1 ATOM 537 C CG . LEU A 1 69 ? -1.036 89.485 20.911 1.00 23.77 ? 69 LEU A CG 1 ATOM 538 C CD1 . LEU A 1 69 ? -2.456 89.295 20.370 1.00 21.46 ? 69 LEU A CD1 1 ATOM 539 C CD2 . LEU A 1 69 ? 0.016 89.395 19.803 1.00 23.22 ? 69 LEU A CD2 1 ATOM 540 N N . GLN A 1 70 ? -0.608 89.917 24.467 1.00 28.87 ? 70 GLN A N 1 ATOM 541 C CA . GLN A 1 70 ? -0.362 88.924 25.496 1.00 31.96 ? 70 GLN A CA 1 ATOM 542 C C . GLN A 1 70 ? -1.429 88.975 26.587 1.00 29.61 ? 70 GLN A C 1 ATOM 543 O O . GLN A 1 70 ? -1.929 87.938 27.018 1.00 31.33 ? 70 GLN A O 1 ATOM 544 C CB . GLN A 1 70 ? 1.024 89.144 26.101 1.00 32.03 ? 70 GLN A CB 1 ATOM 545 C CG . GLN A 1 70 ? 2.155 89.041 25.090 1.00 32.39 ? 70 GLN A CG 1 ATOM 546 C CD . GLN A 1 70 ? 1.987 87.866 24.146 1.00 33.12 ? 70 GLN A CD 1 ATOM 547 O OE1 . GLN A 1 70 ? 1.683 86.751 24.568 1.00 32.33 ? 70 GLN A OE1 1 ATOM 548 N NE2 . GLN A 1 70 ? 2.189 88.109 22.858 1.00 32.03 ? 70 GLN A NE2 1 ATOM 549 N N . LYS A 1 71 ? -1.773 90.175 27.041 1.00 26.87 ? 71 LYS A N 1 ATOM 550 C CA . LYS A 1 71 ? -2.795 90.314 28.072 1.00 22.47 ? 71 LYS A CA 1 ATOM 551 C C . LYS A 1 71 ? -4.088 89.653 27.609 1.00 23.82 ? 71 LYS A C 1 ATOM 552 O O . LYS A 1 71 ? -4.883 89.198 28.424 1.00 23.44 ? 71 LYS A O 1 ATOM 553 C CB . LYS A 1 71 ? -3.076 91.786 28.383 1.00 36.97 ? 71 LYS A CB 1 ATOM 554 C CG . LYS A 1 71 ? -1.928 92.551 28.998 1.00 45.80 ? 71 LYS A CG 1 ATOM 555 C CD . LYS A 1 71 ? -2.332 93.991 29.283 1.00 52.13 ? 71 LYS A CD 1 ATOM 556 C CE . LYS A 1 71 ? -1.136 94.832 29.692 1.00 56.29 ? 71 LYS A CE 1 ATOM 557 N NZ . LYS A 1 71 ? -1.501 96.255 29.890 1.00 53.85 ? 71 LYS A NZ 1 ATOM 558 N N . ALA A 1 72 ? -4.302 89.615 26.298 1.00 18.17 ? 72 ALA A N 1 ATOM 559 C CA . ALA A 1 72 ? -5.497 88.995 25.738 1.00 20.99 ? 72 ALA A CA 1 ATOM 560 C C . ALA A 1 72 ? -5.357 87.471 25.749 1.00 17.56 ? 72 ALA A C 1 ATOM 561 O O . ALA A 1 72 ? -6.274 86.762 26.163 1.00 17.56 ? 72 ALA A O 1 ATOM 562 C CB . ALA A 1 72 ? -5.720 89.489 24.328 1.00 27.39 ? 72 ALA A CB 1 ATOM 563 N N . ARG A 1 73 ? -4.208 86.976 25.292 1.00 7.23 ? 73 ARG A N 1 ATOM 564 C CA . ARG A 1 73 ? -3.939 85.544 25.279 1.00 9.37 ? 73 ARG A CA 1 ATOM 565 C C . ARG A 1 73 ? -4.050 85.017 26.715 1.00 7.23 ? 73 ARG A C 1 ATOM 566 O O . ARG A 1 73 ? -4.635 83.958 26.967 1.00 7.23 ? 73 ARG A O 1 ATOM 567 C CB . ARG A 1 73 ? -2.519 85.260 24.779 1.00 20.74 ? 73 ARG A CB 1 ATOM 568 C CG . ARG A 1 73 ? -2.159 85.792 23.411 1.00 27.69 ? 73 ARG A CG 1 ATOM 569 C CD . ARG A 1 73 ? -2.698 84.931 22.306 1.00 28.89 ? 73 ARG A CD 1 ATOM 570 N NE . ARG A 1 73 ? -2.278 85.412 20.991 1.00 30.33 ? 73 ARG A NE 1 ATOM 571 C CZ . ARG A 1 73 ? -1.053 85.279 20.494 1.00 27.90 ? 73 ARG A CZ 1 ATOM 572 N NH1 . ARG A 1 73 ? -0.112 84.679 21.203 1.00 26.26 ? 73 ARG A NH1 1 ATOM 573 N NH2 . ARG A 1 73 ? -0.774 85.727 19.279 1.00 21.12 ? 73 ARG A NH2 1 ATOM 574 N N . GLU A 1 74 ? -3.469 85.763 27.650 1.00 15.17 ? 74 GLU A N 1 ATOM 575 C CA . GLU A 1 74 ? -3.472 85.384 29.052 1.00 15.17 ? 74 GLU A CA 1 ATOM 576 C C . GLU A 1 74 ? -4.863 85.182 29.630 1.00 15.35 ? 74 GLU A C 1 ATOM 577 O O . GLU A 1 74 ? -5.114 84.208 30.355 1.00 15.17 ? 74 GLU A O 1 ATOM 578 C CB . GLU A 1 74 ? -2.761 86.437 29.883 1.00 18.13 ? 74 GLU A CB 1 ATOM 579 C CG . GLU A 1 74 ? -2.692 86.072 31.342 1.00 18.13 ? 74 GLU A CG 1 ATOM 580 C CD . GLU A 1 74 ? -2.233 87.218 32.199 1.00 22.37 ? 74 GLU A CD 1 ATOM 581 O OE1 . GLU A 1 74 ? -1.372 88.002 31.739 1.00 22.90 ? 74 GLU A OE1 1 ATOM 582 O OE2 . GLU A 1 74 ? -2.726 87.324 33.340 1.00 23.64 ? 74 GLU A OE2 1 ATOM 583 N N . ASP A 1 75 ? -5.772 86.103 29.321 1.00 23.15 ? 75 ASP A N 1 ATOM 584 C CA . ASP A 1 75 ? -7.112 86.000 29.858 1.00 23.15 ? 75 ASP A CA 1 ATOM 585 C C . ASP A 1 75 ? -7.847 84.795 29.316 1.00 23.15 ? 75 ASP A C 1 ATOM 586 O O . ASP A 1 75 ? -8.659 84.212 30.024 1.00 23.15 ? 75 ASP A O 1 ATOM 587 C CB . ASP A 1 75 ? -7.898 87.291 29.621 1.00 53.46 ? 75 ASP A CB 1 ATOM 588 C CG . ASP A 1 75 ? -7.321 88.476 30.398 1.00 67.12 ? 75 ASP A CG 1 ATOM 589 O OD1 . ASP A 1 75 ? -6.840 88.279 31.539 1.00 66.16 ? 75 ASP A OD1 1 ATOM 590 O OD2 . ASP A 1 75 ? -7.356 89.609 29.874 1.00 67.21 ? 75 ASP A OD2 1 ATOM 591 N N . ILE A 1 76 ? -7.568 84.395 28.079 1.00 18.75 ? 76 ILE A N 1 ATOM 592 C CA . ILE A 1 76 ? -8.233 83.206 27.545 1.00 18.75 ? 76 ILE A CA 1 ATOM 593 C C . ILE A 1 76 ? -7.517 81.975 28.103 1.00 18.75 ? 76 ILE A C 1 ATOM 594 O O . ILE A 1 76 ? -8.125 80.943 28.368 1.00 18.75 ? 76 ILE A O 1 ATOM 595 C CB . ILE A 1 76 ? -8.167 83.117 26.008 1.00 23.43 ? 76 ILE A CB 1 ATOM 596 C CG1 . ILE A 1 76 ? -8.785 84.350 25.365 1.00 31.43 ? 76 ILE A CG1 1 ATOM 597 C CG2 . ILE A 1 76 ? -8.940 81.915 25.536 1.00 26.74 ? 76 ILE A CG2 1 ATOM 598 C CD1 . ILE A 1 76 ? -8.738 84.319 23.846 1.00 44.58 ? 76 ILE A CD1 1 ATOM 599 N N . PHE A 1 77 ? -6.211 82.089 28.291 1.00 23.54 ? 77 PHE A N 1 ATOM 600 C CA . PHE A 1 77 ? -5.456 80.961 28.789 1.00 23.54 ? 77 PHE A CA 1 ATOM 601 C C . PHE A 1 77 ? -5.891 80.554 30.179 1.00 23.54 ? 77 PHE A C 1 ATOM 602 O O . PHE A 1 77 ? -6.187 79.391 30.410 1.00 23.54 ? 77 PHE A O 1 ATOM 603 C CB . PHE A 1 77 ? -3.966 81.270 28.796 1.00 13.50 ? 77 PHE A CB 1 ATOM 604 C CG . PHE A 1 77 ? -3.109 80.047 28.876 1.00 13.50 ? 77 PHE A CG 1 ATOM 605 C CD1 . PHE A 1 77 ? -2.645 79.434 27.720 1.00 13.50 ? 77 PHE A CD1 1 ATOM 606 C CD2 . PHE A 1 77 ? -2.807 79.477 30.101 1.00 13.50 ? 77 PHE A CD2 1 ATOM 607 C CE1 . PHE A 1 77 ? -1.893 78.269 27.779 1.00 13.50 ? 77 PHE A CE1 1 ATOM 608 C CE2 . PHE A 1 77 ? -2.056 78.308 30.171 1.00 13.50 ? 77 PHE A CE2 1 ATOM 609 C CZ . PHE A 1 77 ? -1.597 77.703 29.008 1.00 13.50 ? 77 PHE A CZ 1 ATOM 610 N N . MET A 1 78 ? -5.934 81.502 31.108 1.00 19.62 ? 78 MET A N 1 ATOM 611 C CA . MET A 1 78 ? -6.332 81.175 32.472 1.00 19.62 ? 78 MET A CA 1 ATOM 612 C C . MET A 1 78 ? -7.803 80.755 32.595 1.00 19.62 ? 78 MET A C 1 ATOM 613 O O . MET A 1 78 ? -8.149 79.930 33.444 1.00 19.62 ? 78 MET A O 1 ATOM 614 C CB . MET A 1 78 ? -6.055 82.355 33.393 1.00 24.14 ? 78 MET A CB 1 ATOM 615 C CG . MET A 1 78 ? -4.642 82.902 33.294 1.00 24.14 ? 78 MET A CG 1 ATOM 616 S SD . MET A 1 78 ? -3.317 81.735 33.666 1.00 24.14 ? 78 MET A SD 1 ATOM 617 C CE . MET A 1 78 ? -3.633 81.355 35.369 1.00 24.14 ? 78 MET A CE 1 ATOM 618 N N . GLU A 1 79 ? -8.664 81.314 31.746 1.00 14.15 ? 79 GLU A N 1 ATOM 619 C CA . GLU A 1 79 ? -10.083 80.976 31.778 1.00 14.15 ? 79 GLU A CA 1 ATOM 620 C C . GLU A 1 79 ? -10.228 79.508 31.424 1.00 14.15 ? 79 GLU A C 1 ATOM 621 O O . GLU A 1 79 ? -11.016 78.787 32.012 1.00 14.15 ? 79 GLU A O 1 ATOM 622 C CB . GLU A 1 79 ? -10.868 81.825 30.780 1.00 70.79 ? 79 GLU A CB 1 ATOM 623 C CG . GLU A 1 79 ? -12.374 81.799 31.005 1.00 83.91 ? 79 GLU A CG 1 ATOM 624 C CD . GLU A 1 79 ? -13.143 82.522 29.912 1.00 93.29 ? 79 GLU A CD 1 ATOM 625 O OE1 . GLU A 1 79 ? -12.696 83.613 29.493 1.00 89.78 ? 79 GLU A OE1 1 ATOM 626 O OE2 . GLU A 1 79 ? -14.198 82.006 29.477 1.00 95.53 ? 79 GLU A OE2 1 ATOM 627 N N . THR A 1 80 ? -9.442 79.073 30.453 1.00 17.77 ? 80 THR A N 1 ATOM 628 C CA . THR A 1 80 ? -9.466 77.696 30.011 1.00 17.77 ? 80 THR A CA 1 ATOM 629 C C . THR A 1 80 ? -9.041 76.836 31.175 1.00 17.77 ? 80 THR A C 1 ATOM 630 O O . THR A 1 80 ? -9.635 75.788 31.441 1.00 17.77 ? 80 THR A O 1 ATOM 631 C CB . THR A 1 80 ? -8.512 77.509 28.840 1.00 29.69 ? 80 THR A CB 1 ATOM 632 O OG1 . THR A 1 80 ? -8.975 78.306 27.747 1.00 29.69 ? 80 THR A OG1 1 ATOM 633 C CG2 . THR A 1 80 ? -8.455 76.060 28.406 1.00 29.69 ? 80 THR A CG2 1 ATOM 634 N N . LEU A 1 81 ? -8.012 77.291 31.880 1.00 19.28 ? 81 LEU A N 1 ATOM 635 C CA . LEU A 1 81 ? -7.515 76.565 33.032 1.00 19.28 ? 81 LEU A CA 1 ATOM 636 C C . LEU A 1 81 ? -8.603 76.543 34.103 1.00 19.28 ? 81 LEU A C 1 ATOM 637 O O . LEU A 1 81 ? -8.821 75.515 34.757 1.00 19.28 ? 81 LEU A O 1 ATOM 638 C CB . LEU A 1 81 ? -6.253 77.239 33.568 1.00 4.65 ? 81 LEU A CB 1 ATOM 639 C CG . LEU A 1 81 ? -5.619 76.569 34.787 1.00 4.65 ? 81 LEU A CG 1 ATOM 640 C CD1 . LEU A 1 81 ? -5.464 75.083 34.525 1.00 4.65 ? 81 LEU A CD1 1 ATOM 641 C CD2 . LEU A 1 81 ? -4.298 77.220 35.106 1.00 4.65 ? 81 LEU A CD2 1 ATOM 642 N N . LYS A 1 82 ? -9.287 77.680 34.268 1.00 12.14 ? 82 LYS A N 1 ATOM 643 C CA . LYS A 1 82 ? -10.358 77.801 35.246 1.00 12.14 ? 82 LYS A CA 1 ATOM 644 C C . LYS A 1 82 ? -11.407 76.726 34.985 1.00 12.14 ? 82 LYS A C 1 ATOM 645 O O . LYS A 1 82 ? -11.770 75.974 35.881 1.00 12.14 ? 82 LYS A O 1 ATOM 646 C CB . LYS A 1 82 ? -11.007 79.181 35.160 1.00 58.30 ? 82 LYS A CB 1 ATOM 647 C CG . LYS A 1 82 ? -11.584 79.670 36.486 1.00 70.94 ? 82 LYS A CG 1 ATOM 648 C CD . LYS A 1 82 ? -12.427 80.934 36.332 1.00 81.13 ? 82 LYS A CD 1 ATOM 649 C CE . LYS A 1 82 ? -13.873 80.613 35.960 1.00 87.30 ? 82 LYS A CE 1 ATOM 650 N NZ . LYS A 1 82 ? -13.997 79.899 34.662 1.00 91.25 ? 82 LYS A NZ 1 ATOM 651 N N . ASP A 1 83 ? -11.881 76.652 33.748 1.00 14.17 ? 83 ASP A N 1 ATOM 652 C CA . ASP A 1 83 ? -12.884 75.665 33.371 1.00 14.17 ? 83 ASP A CA 1 ATOM 653 C C . ASP A 1 83 ? -12.430 74.212 33.598 1.00 14.17 ? 83 ASP A C 1 ATOM 654 O O . ASP A 1 83 ? -13.242 73.353 33.939 1.00 14.17 ? 83 ASP A O 1 ATOM 655 C CB . ASP A 1 83 ? -13.286 75.846 31.902 1.00 18.47 ? 83 ASP A CB 1 ATOM 656 C CG . ASP A 1 83 ? -13.730 77.270 31.577 1.00 34.53 ? 83 ASP A CG 1 ATOM 657 O OD1 . ASP A 1 83 ? -14.219 77.968 32.490 1.00 33.44 ? 83 ASP A OD1 1 ATOM 658 O OD2 . ASP A 1 83 ? -13.609 77.683 30.399 1.00 36.02 ? 83 ASP A OD2 1 ATOM 659 N N . ILE A 1 84 ? -11.147 73.921 33.404 1.00 13.96 ? 84 ILE A N 1 ATOM 660 C CA . ILE A 1 84 ? -10.669 72.555 33.608 1.00 13.96 ? 84 ILE A CA 1 ATOM 661 C C . ILE A 1 84 ? -10.765 72.195 35.089 1.00 13.96 ? 84 ILE A C 1 ATOM 662 O O . ILE A 1 84 ? -11.347 71.179 35.449 1.00 13.96 ? 84 ILE A O 1 ATOM 663 C CB . ILE A 1 84 ? -9.207 72.376 33.133 1.00 8.10 ? 84 ILE A CB 1 ATOM 664 C CG1 . ILE A 1 84 ? -9.094 72.684 31.634 1.00 8.10 ? 84 ILE A CG1 1 ATOM 665 C CG2 . ILE A 1 84 ? -8.757 70.961 33.391 1.00 8.10 ? 84 ILE A CG2 1 ATOM 666 C CD1 . ILE A 1 84 ? -7.676 72.709 31.092 1.00 8.10 ? 84 ILE A CD1 1 ATOM 667 N N . VAL A 1 85 ? -10.194 73.035 35.944 1.00 14.63 ? 85 VAL A N 1 ATOM 668 C CA . VAL A 1 85 ? -10.241 72.823 37.389 1.00 14.63 ? 85 VAL A CA 1 ATOM 669 C C . VAL A 1 85 ? -11.707 72.803 37.850 1.00 14.87 ? 85 VAL A C 1 ATOM 670 O O . VAL A 1 85 ? -12.085 72.047 38.743 1.00 16.84 ? 85 VAL A O 1 ATOM 671 C CB . VAL A 1 85 ? -9.486 73.948 38.124 1.00 18.01 ? 85 VAL A CB 1 ATOM 672 C CG1 . VAL A 1 85 ? -9.590 73.759 39.600 1.00 21.28 ? 85 VAL A CG1 1 ATOM 673 C CG2 . VAL A 1 85 ? -8.036 73.952 37.714 1.00 15.74 ? 85 VAL A CG2 1 ATOM 674 N N . GLU A 1 86 ? -12.525 73.648 37.230 1.00 15.20 ? 86 GLU A N 1 ATOM 675 C CA . GLU A 1 86 ? -13.945 73.718 37.538 1.00 21.54 ? 86 GLU A CA 1 ATOM 676 C C . GLU A 1 86 ? -14.532 72.337 37.254 1.00 22.84 ? 86 GLU A C 1 ATOM 677 O O . GLU A 1 86 ? -15.113 71.708 38.129 1.00 19.51 ? 86 GLU A O 1 ATOM 678 C CB . GLU A 1 86 ? -14.628 74.756 36.640 1.00 44.19 ? 86 GLU A CB 1 ATOM 679 C CG . GLU A 1 86 ? -15.516 75.775 37.358 1.00 68.47 ? 86 GLU A CG 1 ATOM 680 C CD . GLU A 1 86 ? -14.734 76.921 38.003 1.00 79.46 ? 86 GLU A CD 1 ATOM 681 O OE1 . GLU A 1 86 ? -13.935 76.666 38.932 1.00 88.13 ? 86 GLU A OE1 1 ATOM 682 O OE2 . GLU A 1 86 ? -14.923 78.084 37.577 1.00 74.46 ? 86 GLU A OE2 1 ATOM 683 N N . TYR A 1 87 ? -14.358 71.864 36.023 1.00 28.13 ? 87 TYR A N 1 ATOM 684 C CA . TYR A 1 87 ? -14.883 70.563 35.616 1.00 25.99 ? 87 TYR A CA 1 ATOM 685 C C . TYR A 1 87 ? -14.572 69.472 36.621 1.00 25.99 ? 87 TYR A C 1 ATOM 686 O O . TYR A 1 87 ? -15.467 68.741 37.039 1.00 25.99 ? 87 TYR A O 1 ATOM 687 C CB . TYR A 1 87 ? -14.321 70.154 34.247 1.00 4.65 ? 87 TYR A CB 1 ATOM 688 C CG . TYR A 1 87 ? -14.732 68.753 33.770 1.00 4.65 ? 87 TYR A CG 1 ATOM 689 C CD1 . TYR A 1 87 ? -15.976 68.531 33.173 1.00 4.65 ? 87 TYR A CD1 1 ATOM 690 C CD2 . TYR A 1 87 ? -13.889 67.651 33.961 1.00 4.65 ? 87 TYR A CD2 1 ATOM 691 C CE1 . TYR A 1 87 ? -16.370 67.253 32.790 1.00 11.11 ? 87 TYR A CE1 1 ATOM 692 C CE2 . TYR A 1 87 ? -14.272 66.380 33.579 1.00 8.06 ? 87 TYR A CE2 1 ATOM 693 C CZ . TYR A 1 87 ? -15.516 66.184 32.998 1.00 6.06 ? 87 TYR A CZ 1 ATOM 694 O OH . TYR A 1 87 ? -15.922 64.911 32.653 1.00 8.04 ? 87 TYR A OH 1 ATOM 695 N N . TYR A 1 88 ? -13.304 69.367 37.005 1.00 21.34 ? 88 TYR A N 1 ATOM 696 C CA . TYR A 1 88 ? -12.872 68.340 37.944 1.00 21.34 ? 88 TYR A CA 1 ATOM 697 C C . TYR A 1 88 ? -13.198 68.581 39.405 1.00 26.04 ? 88 TYR A C 1 ATOM 698 O O . TYR A 1 88 ? -12.754 67.827 40.272 1.00 23.79 ? 88 TYR A O 1 ATOM 699 C CB . TYR A 1 88 ? -11.379 68.093 37.796 1.00 26.16 ? 88 TYR A CB 1 ATOM 700 C CG . TYR A 1 88 ? -11.065 67.253 36.595 1.00 26.16 ? 88 TYR A CG 1 ATOM 701 C CD1 . TYR A 1 88 ? -10.432 67.794 35.481 1.00 26.16 ? 88 TYR A CD1 1 ATOM 702 C CD2 . TYR A 1 88 ? -11.458 65.921 36.549 1.00 26.16 ? 88 TYR A CD2 1 ATOM 703 C CE1 . TYR A 1 88 ? -10.204 67.027 34.352 1.00 26.16 ? 88 TYR A CE1 1 ATOM 704 C CE2 . TYR A 1 88 ? -11.241 65.149 35.431 1.00 30.69 ? 88 TYR A CE2 1 ATOM 705 C CZ . TYR A 1 88 ? -10.616 65.702 34.335 1.00 26.16 ? 88 TYR A CZ 1 ATOM 706 O OH . TYR A 1 88 ? -10.412 64.919 33.223 1.00 26.47 ? 88 TYR A OH 1 ATOM 707 N N . LYS A 1 89 ? -13.976 69.627 39.672 1.00 57.49 ? 89 LYS A N 1 ATOM 708 C CA . LYS A 1 89 ? -14.383 69.968 41.029 1.00 67.36 ? 89 LYS A CA 1 ATOM 709 C C . LYS A 1 89 ? -13.223 69.931 42.008 1.00 67.00 ? 89 LYS A C 1 ATOM 710 O O . LYS A 1 89 ? -13.314 69.304 43.061 1.00 66.99 ? 89 LYS A O 1 ATOM 711 C CB . LYS A 1 89 ? -15.475 69.009 41.499 1.00 66.28 ? 89 LYS A CB 1 ATOM 712 C CG . LYS A 1 89 ? -16.750 69.101 40.697 1.00 73.34 ? 89 LYS A CG 1 ATOM 713 C CD . LYS A 1 89 ? -17.758 68.044 41.119 1.00 83.07 ? 89 LYS A CD 1 ATOM 714 C CE . LYS A 1 89 ? -19.035 68.162 40.297 1.00 84.40 ? 89 LYS A CE 1 ATOM 715 N NZ . LYS A 1 89 ? -20.070 67.166 40.685 1.00 93.31 ? 89 LYS A NZ 1 ATOM 716 N N . ASP A 1 90 ? -12.128 70.598 41.661 1.00 42.50 ? 90 ASP A N 1 ATOM 717 C CA . ASP A 1 90 ? -10.972 70.626 42.544 1.00 41.87 ? 90 ASP A CA 1 ATOM 718 C C . ASP A 1 90 ? -10.180 71.917 42.456 1.00 43.52 ? 90 ASP A C 1 ATOM 719 O O . ASP A 1 90 ? -9.047 71.916 41.988 1.00 40.19 ? 90 ASP A O 1 ATOM 720 C CB . ASP A 1 90 ? -10.039 69.454 42.252 1.00 49.29 ? 90 ASP A CB 1 ATOM 721 C CG . ASP A 1 90 ? -8.838 69.436 43.175 1.00 59.42 ? 90 ASP A CG 1 ATOM 722 O OD1 . ASP A 1 90 ? -9.033 69.352 44.404 1.00 66.61 ? 90 ASP A OD1 1 ATOM 723 O OD2 . ASP A 1 90 ? -7.701 69.517 42.675 1.00 56.87 ? 90 ASP A OD2 1 ATOM 724 N N . SER A 1 91 ? -10.777 73.011 42.920 1.00 20.04 ? 91 SER A N 1 ATOM 725 C CA . SER A 1 91 ? -10.123 74.312 42.906 1.00 28.29 ? 91 SER A CA 1 ATOM 726 C C . SER A 1 91 ? -9.209 74.529 44.118 1.00 28.03 ? 91 SER A C 1 ATOM 727 O O . SER A 1 91 ? -8.566 75.566 44.236 1.00 30.21 ? 91 SER A O 1 ATOM 728 C CB . SER A 1 91 ? -11.175 75.423 42.828 1.00 66.27 ? 91 SER A CB 1 ATOM 729 O OG . SER A 1 91 ? -12.147 75.279 43.844 1.00 80.71 ? 91 SER A OG 1 ATOM 730 N N . THR A 1 92 ? -9.148 73.543 45.008 1.00 78.78 ? 92 THR A N 1 ATOM 731 C CA . THR A 1 92 ? -8.307 73.630 46.203 1.00 82.94 ? 92 THR A CA 1 ATOM 732 C C . THR A 1 92 ? -6.898 73.138 45.902 1.00 82.14 ? 92 THR A C 1 ATOM 733 O O . THR A 1 92 ? -5.958 73.425 46.643 1.00 79.75 ? 92 THR A O 1 ATOM 734 C CB . THR A 1 92 ? -8.866 72.772 47.361 1.00 76.96 ? 92 THR A CB 1 ATOM 735 O OG1 . THR A 1 92 ? -8.789 71.383 47.013 1.00 85.28 ? 92 THR A OG1 1 ATOM 736 C CG2 . THR A 1 92 ? -10.312 73.136 47.642 1.00 79.75 ? 92 THR A CG2 1 ATOM 737 N N . GLY A 1 93 ? -6.767 72.387 44.813 1.00 50.71 ? 93 GLY A N 1 ATOM 738 C CA . GLY A 1 93 ? -5.475 71.856 44.424 1.00 48.28 ? 93 GLY A CA 1 ATOM 739 C C . GLY A 1 93 ? -4.705 72.809 43.533 1.00 38.46 ? 93 GLY A C 1 ATOM 740 O O . GLY A 1 93 ? -5.234 73.840 43.091 1.00 36.36 ? 93 GLY A O 1 ATOM 741 N N . SER A 1 94 ? -3.451 72.461 43.266 1.00 71.14 ? 94 SER A N 1 ATOM 742 C CA . SER A 1 94 ? -2.583 73.274 42.426 1.00 68.52 ? 94 SER A CA 1 ATOM 743 C C . SER A 1 94 ? -2.356 72.615 41.063 1.00 58.61 ? 94 SER A C 1 ATOM 744 O O . SER A 1 94 ? -1.606 71.641 40.950 1.00 60.19 ? 94 SER A O 1 ATOM 745 C CB . SER A 1 94 ? -1.251 73.491 43.133 1.00 24.46 ? 94 SER A CB 1 ATOM 746 O OG . SER A 1 94 ? -0.296 74.010 42.236 1.00 31.67 ? 94 SER A OG 1 ATOM 747 N N . HIS A 1 95 ? -2.993 73.161 40.028 1.00 15.74 ? 95 HIS A N 1 ATOM 748 C CA . HIS A 1 95 ? -2.882 72.610 38.680 1.00 15.74 ? 95 HIS A CA 1 ATOM 749 C C . HIS A 1 95 ? -2.109 73.456 37.682 1.00 15.74 ? 95 HIS A C 1 ATOM 750 O O . HIS A 1 95 ? -1.827 74.629 37.922 1.00 15.74 ? 95 HIS A O 1 ATOM 751 C CB . HIS A 1 95 ? -4.277 72.313 38.152 1.00 19.57 ? 95 HIS A CB 1 ATOM 752 C CG . HIS A 1 95 ? -5.084 71.485 39.092 1.00 19.57 ? 95 HIS A CG 1 ATOM 753 N ND1 . HIS A 1 95 ? -4.806 70.160 39.333 1.00 19.57 ? 95 HIS A ND1 1 ATOM 754 C CD2 . HIS A 1 95 ? -6.093 71.818 39.928 1.00 19.57 ? 95 HIS A CD2 1 ATOM 755 C CE1 . HIS A 1 95 ? -5.607 69.711 40.281 1.00 20.78 ? 95 HIS A CE1 1 ATOM 756 N NE2 . HIS A 1 95 ? -6.397 70.698 40.660 1.00 19.57 ? 95 HIS A NE2 1 ATOM 757 N N . VAL A 1 96 ? -1.780 72.856 36.546 1.00 19.96 ? 96 VAL A N 1 ATOM 758 C CA . VAL A 1 96 ? -0.991 73.552 35.535 1.00 19.96 ? 96 VAL A CA 1 ATOM 759 C C . VAL A 1 96 ? -1.458 73.282 34.122 1.00 19.96 ? 96 VAL A C 1 ATOM 760 O O . VAL A 1 96 ? -1.901 72.186 33.803 1.00 19.96 ? 96 VAL A O 1 ATOM 761 C CB . VAL A 1 96 ? 0.509 73.143 35.639 1.00 8.12 ? 96 VAL A CB 1 ATOM 762 C CG1 . VAL A 1 96 ? 0.643 71.635 35.441 1.00 8.12 ? 96 VAL A CG1 1 ATOM 763 C CG2 . VAL A 1 96 ? 1.346 73.915 34.635 1.00 8.12 ? 96 VAL A CG2 1 ATOM 764 N N . LEU A 1 97 ? -1.363 74.303 33.284 1.00 4.65 ? 97 LEU A N 1 ATOM 765 C CA . LEU A 1 97 ? -1.737 74.177 31.893 1.00 4.65 ? 97 LEU A CA 1 ATOM 766 C C . LEU A 1 97 ? -0.600 74.753 31.053 1.00 4.65 ? 97 LEU A C 1 ATOM 767 O O . LEU A 1 97 ? -0.223 75.917 31.208 1.00 4.65 ? 97 LEU A O 1 ATOM 768 C CB . LEU A 1 97 ? -3.042 74.928 31.596 1.00 5.91 ? 97 LEU A CB 1 ATOM 769 C CG . LEU A 1 97 ? -3.523 74.813 30.137 1.00 5.91 ? 97 LEU A CG 1 ATOM 770 C CD1 . LEU A 1 97 ? -4.042 73.406 29.884 1.00 5.91 ? 97 LEU A CD1 1 ATOM 771 C CD2 . LEU A 1 97 ? -4.583 75.849 29.835 1.00 5.91 ? 97 LEU A CD2 1 ATOM 772 N N . GLN A 1 98 ? -0.043 73.915 30.186 1.00 4.65 ? 98 GLN A N 1 ATOM 773 C CA . GLN A 1 98 ? 1.024 74.332 29.302 1.00 4.65 ? 98 GLN A CA 1 ATOM 774 C C . GLN A 1 98 ? 0.523 74.263 27.874 1.00 4.65 ? 98 GLN A C 1 ATOM 775 O O . GLN A 1 98 ? -0.216 73.364 27.514 1.00 4.65 ? 98 GLN A O 1 ATOM 776 C CB . GLN A 1 98 ? 2.239 73.436 29.474 1.00 15.95 ? 98 GLN A CB 1 ATOM 777 C CG . GLN A 1 98 ? 3.176 73.907 30.563 1.00 15.95 ? 98 GLN A CG 1 ATOM 778 C CD . GLN A 1 98 ? 3.659 72.804 31.485 1.00 15.95 ? 98 GLN A CD 1 ATOM 779 O OE1 . GLN A 1 98 ? 4.778 72.868 31.978 1.00 15.95 ? 98 GLN A OE1 1 ATOM 780 N NE2 . GLN A 1 98 ? 2.817 71.804 31.737 1.00 15.95 ? 98 GLN A NE2 1 ATOM 781 N N . GLY A 1 99 ? 0.907 75.237 27.066 1.00 8.91 ? 99 GLY A N 1 ATOM 782 C CA . GLY A 1 99 ? 0.488 75.269 25.685 1.00 8.91 ? 99 GLY A CA 1 ATOM 783 C C . GLY A 1 99 ? 1.717 75.556 24.864 1.00 8.91 ? 99 GLY A C 1 ATOM 784 O O . GLY A 1 99 ? 2.634 76.247 25.301 1.00 8.91 ? 99 GLY A O 1 ATOM 785 N N . ARG A 1 100 ? 1.748 75.032 23.657 1.00 5.57 ? 100 ARG A N 1 ATOM 786 C CA . ARG A 1 100 ? 2.902 75.246 22.817 1.00 5.57 ? 100 ARG A CA 1 ATOM 787 C C . ARG A 1 100 ? 2.450 75.450 21.403 1.00 5.57 ? 100 ARG A C 1 ATOM 788 O O . ARG A 1 100 ? 1.686 74.661 20.886 1.00 5.57 ? 100 ARG A O 1 ATOM 789 C CB . ARG A 1 100 ? 3.814 74.032 22.908 1.00 25.98 ? 100 ARG A CB 1 ATOM 790 C CG . ARG A 1 100 ? 4.863 73.965 21.851 1.00 25.98 ? 100 ARG A CG 1 ATOM 791 C CD . ARG A 1 100 ? 6.021 73.175 22.357 1.00 26.25 ? 100 ARG A CD 1 ATOM 792 N NE . ARG A 1 100 ? 7.076 73.019 21.367 1.00 34.99 ? 100 ARG A NE 1 ATOM 793 C CZ . ARG A 1 100 ? 7.000 72.193 20.336 1.00 33.35 ? 100 ARG A CZ 1 ATOM 794 N NH1 . ARG A 1 100 ? 5.913 71.446 20.161 1.00 26.32 ? 100 ARG A NH1 1 ATOM 795 N NH2 . ARG A 1 100 ? 8.009 72.112 19.482 1.00 28.45 ? 100 ARG A NH2 1 ATOM 796 N N . PHE A 1 101 ? 2.892 76.520 20.770 1.00 13.50 ? 101 PHE A N 1 ATOM 797 C CA . PHE A 1 101 ? 2.493 76.719 19.397 1.00 13.50 ? 101 PHE A CA 1 ATOM 798 C C . PHE A 1 101 ? 3.530 77.515 18.657 1.00 13.50 ? 101 PHE A C 1 ATOM 799 O O . PHE A 1 101 ? 4.315 78.228 19.257 1.00 13.50 ? 101 PHE A O 1 ATOM 800 C CB . PHE A 1 101 ? 1.124 77.386 19.324 1.00 44.57 ? 101 PHE A CB 1 ATOM 801 C CG . PHE A 1 101 ? 1.128 78.810 19.722 1.00 44.57 ? 101 PHE A CG 1 ATOM 802 C CD1 . PHE A 1 101 ? 1.334 79.803 18.772 1.00 44.57 ? 101 PHE A CD1 1 ATOM 803 C CD2 . PHE A 1 101 ? 0.931 79.170 21.054 1.00 44.57 ? 101 PHE A CD2 1 ATOM 804 C CE1 . PHE A 1 101 ? 1.343 81.140 19.141 1.00 44.57 ? 101 PHE A CE1 1 ATOM 805 C CE2 . PHE A 1 101 ? 0.939 80.509 21.440 1.00 44.57 ? 101 PHE A CE2 1 ATOM 806 C CZ . PHE A 1 101 ? 1.144 81.499 20.483 1.00 47.83 ? 101 PHE A CZ 1 ATOM 807 N N . GLY A 1 102 ? 3.547 77.355 17.343 1.00 12.80 ? 102 GLY A N 1 ATOM 808 C CA . GLY A 1 102 ? 4.517 78.050 16.525 1.00 12.80 ? 102 GLY A CA 1 ATOM 809 C C . GLY A 1 102 ? 4.558 77.375 15.179 1.00 12.80 ? 102 GLY A C 1 ATOM 810 O O . GLY A 1 102 ? 3.704 76.547 14.881 1.00 12.80 ? 102 GLY A O 1 ATOM 811 N N . CYS A 1 103 ? 5.547 77.710 14.367 1.00 12.97 ? 103 CYS A N 1 ATOM 812 C CA . CYS A 1 103 ? 5.650 77.114 13.046 1.00 12.97 ? 103 CYS A CA 1 ATOM 813 C C . CYS A 1 103 ? 7.088 77.130 12.562 1.00 12.97 ? 103 CYS A C 1 ATOM 814 O O . CYS A 1 103 ? 7.969 77.636 13.244 1.00 12.97 ? 103 CYS A O 1 ATOM 815 C CB . CYS A 1 103 ? 4.786 77.899 12.070 1.00 27.75 ? 103 CYS A CB 1 ATOM 816 S SG . CYS A 1 103 ? 5.350 79.591 11.830 1.00 27.75 ? 103 CYS A SG 1 ATOM 817 N N . GLU A 1 104 ? 7.332 76.569 11.386 1.00 29.72 ? 104 GLU A N 1 ATOM 818 C CA . GLU A 1 104 ? 8.679 76.585 10.838 1.00 29.72 ? 104 GLU A CA 1 ATOM 819 C C . GLU A 1 104 ? 8.691 76.561 9.318 1.00 29.72 ? 104 GLU A C 1 ATOM 820 O O . GLU A 1 104 ? 7.771 76.047 8.684 1.00 29.72 ? 104 GLU A O 1 ATOM 821 C CB . GLU A 1 104 ? 9.513 75.423 11.385 1.00 35.54 ? 104 GLU A CB 1 ATOM 822 C CG . GLU A 1 104 ? 9.151 74.056 10.859 1.00 61.00 ? 104 GLU A CG 1 ATOM 823 C CD . GLU A 1 104 ? 10.154 73.004 11.286 1.00 75.42 ? 104 GLU A CD 1 ATOM 824 O OE1 . GLU A 1 104 ? 11.344 73.157 10.947 1.00 74.04 ? 104 GLU A OE1 1 ATOM 825 O OE2 . GLU A 1 104 ? 9.758 72.030 11.959 1.00 73.47 ? 104 GLU A OE2 1 ATOM 826 N N . ILE A 1 105 ? 9.734 77.156 8.748 1.00 22.98 ? 105 ILE A N 1 ATOM 827 C CA . ILE A 1 105 ? 9.917 77.208 7.304 1.00 23.34 ? 105 ILE A CA 1 ATOM 828 C C . ILE A 1 105 ? 11.264 76.573 6.986 1.00 26.76 ? 105 ILE A C 1 ATOM 829 O O . ILE A 1 105 ? 12.105 76.404 7.866 1.00 24.18 ? 105 ILE A O 1 ATOM 830 C CB . ILE A 1 105 ? 9.925 78.665 6.776 1.00 28.04 ? 105 ILE A CB 1 ATOM 831 C CG1 . ILE A 1 105 ? 11.073 79.441 7.412 1.00 36.88 ? 105 ILE A CG1 1 ATOM 832 C CG2 . ILE A 1 105 ? 8.611 79.353 7.092 1.00 23.31 ? 105 ILE A CG2 1 ATOM 833 C CD1 . ILE A 1 105 ? 11.132 80.881 6.986 1.00 41.52 ? 105 ILE A CD1 1 ATOM 834 N N . GLU A 1 106 ? 11.454 76.189 5.735 1.00 22.51 ? 106 GLU A N 1 ATOM 835 C CA . GLU A 1 106 ? 12.711 75.608 5.303 1.00 28.38 ? 106 GLU A CA 1 ATOM 836 C C . GLU A 1 106 ? 12.810 75.938 3.834 1.00 32.57 ? 106 GLU A C 1 ATOM 837 O O . GLU A 1 106 ? 11.983 75.500 3.037 1.00 33.43 ? 106 GLU A O 1 ATOM 838 C CB . GLU A 1 106 ? 12.744 74.096 5.519 1.00 7.18 ? 106 GLU A CB 1 ATOM 839 C CG . GLU A 1 106 ? 14.053 73.455 5.074 1.00 24.10 ? 106 GLU A CG 1 ATOM 840 C CD . GLU A 1 106 ? 14.326 72.096 5.725 1.00 35.31 ? 106 GLU A CD 1 ATOM 841 O OE1 . GLU A 1 106 ? 13.411 71.247 5.754 1.00 40.31 ? 106 GLU A OE1 1 ATOM 842 O OE2 . GLU A 1 106 ? 15.464 71.868 6.200 1.00 39.00 ? 106 GLU A OE2 1 ATOM 843 N N . ASN A 1 107 ? 13.808 76.743 3.485 1.00 44.02 ? 107 ASN A N 1 ATOM 844 C CA . ASN A 1 107 ? 14.007 77.151 2.104 1.00 41.13 ? 107 ASN A CA 1 ATOM 845 C C . ASN A 1 107 ? 12.864 78.076 1.723 1.00 37.85 ? 107 ASN A C 1 ATOM 846 O O . ASN A 1 107 ? 12.376 78.039 0.597 1.00 41.63 ? 107 ASN A O 1 ATOM 847 C CB . ASN A 1 107 ? 14.032 75.929 1.178 1.00 87.17 ? 107 ASN A CB 1 ATOM 848 C CG . ASN A 1 107 ? 15.102 74.920 1.570 1.00 98.83 ? 107 ASN A CG 1 ATOM 849 O OD1 . ASN A 1 107 ? 15.163 73.822 1.020 1.00 100.32 ? 107 ASN A OD1 1 ATOM 850 N ND2 . ASN A 1 107 ? 15.951 75.293 2.522 1.00 101.23 ? 107 ASN A ND2 1 ATOM 851 N N . ASN A 1 108 ? 12.444 78.903 2.678 1.00 31.52 ? 108 ASN A N 1 ATOM 852 C CA . ASN A 1 108 ? 11.361 79.858 2.466 1.00 39.33 ? 108 ASN A CA 1 ATOM 853 C C . ASN A 1 108 ? 10.046 79.116 2.196 1.00 41.24 ? 108 ASN A C 1 ATOM 854 O O . ASN A 1 108 ? 9.098 79.661 1.651 1.00 39.60 ? 108 ASN A O 1 ATOM 855 C CB . ASN A 1 108 ? 11.764 80.838 1.336 1.00 64.51 ? 108 ASN A CB 1 ATOM 856 C CG . ASN A 1 108 ? 10.583 81.583 0.724 1.00 81.27 ? 108 ASN A CG 1 ATOM 857 O OD1 . ASN A 1 108 ? 9.823 81.001 -0.055 1.00 96.82 ? 108 ASN A OD1 1 ATOM 858 N ND2 . ASN A 1 108 ? 10.425 82.866 1.044 1.00 79.63 ? 108 ASN A ND2 1 ATOM 859 N N . ARG A 1 109 ? 9.991 77.860 2.622 1.00 41.34 ? 109 ARG A N 1 ATOM 860 C CA . ARG A 1 109 ? 8.789 77.044 2.457 1.00 46.24 ? 109 ARG A CA 1 ATOM 861 C C . ARG A 1 109 ? 8.253 76.566 3.813 1.00 39.18 ? 109 ARG A C 1 ATOM 862 O O . ARG A 1 109 ? 8.946 75.835 4.530 1.00 33.64 ? 109 ARG A O 1 ATOM 863 C CB . ARG A 1 109 ? 9.089 75.810 1.594 1.00 80.04 ? 109 ARG A CB 1 ATOM 864 C CG . ARG A 1 109 ? 9.516 76.110 0.172 1.00 102.53 ? 109 ARG A CG 1 ATOM 865 C CD . ARG A 1 109 ? 8.349 76.530 -0.706 1.00 112.45 ? 109 ARG A CD 1 ATOM 866 N NE . ARG A 1 109 ? 8.817 77.075 -1.978 1.00 121.82 ? 109 ARG A NE 1 ATOM 867 C CZ . ARG A 1 109 ? 8.025 77.418 -2.988 1.00 126.99 ? 109 ARG A CZ 1 ATOM 868 N NH1 . ARG A 1 109 ? 6.710 77.271 -2.888 1.00 129.55 ? 109 ARG A NH1 1 ATOM 869 N NH2 . ARG A 1 109 ? 8.551 77.923 -4.097 1.00 127.15 ? 109 ARG A NH2 1 ATOM 870 N N . SER A 1 110 ? 7.035 76.974 4.171 1.00 13.46 ? 110 SER A N 1 ATOM 871 C CA . SER A 1 110 ? 6.452 76.511 5.428 1.00 13.09 ? 110 SER A CA 1 ATOM 872 C C . SER A 1 110 ? 6.601 74.995 5.467 1.00 15.40 ? 110 SER A C 1 ATOM 873 O O . SER A 1 110 ? 6.134 74.299 4.562 1.00 15.84 ? 110 SER A O 1 ATOM 874 C CB . SER A 1 110 ? 4.981 76.886 5.508 1.00 28.36 ? 110 SER A CB 1 ATOM 875 O OG . SER A 1 110 ? 4.850 78.290 5.571 1.00 30.43 ? 110 SER A OG 1 ATOM 876 N N . SER A 1 111 ? 7.262 74.499 6.513 1.00 12.43 ? 111 SER A N 1 ATOM 877 C CA . SER A 1 111 ? 7.513 73.074 6.663 1.00 11.44 ? 111 SER A CA 1 ATOM 878 C C . SER A 1 111 ? 6.982 72.468 7.948 1.00 11.44 ? 111 SER A C 1 ATOM 879 O O . SER A 1 111 ? 7.147 71.273 8.178 1.00 17.51 ? 111 SER A O 1 ATOM 880 C CB . SER A 1 111 ? 9.007 72.811 6.596 1.00 22.32 ? 111 SER A CB 1 ATOM 881 O OG . SER A 1 111 ? 9.643 73.314 7.753 1.00 26.84 ? 111 SER A OG 1 ATOM 882 N N . GLY A 1 112 ? 6.351 73.281 8.789 1.00 19.21 ? 112 GLY A N 1 ATOM 883 C CA . GLY A 1 112 ? 5.826 72.764 10.043 1.00 18.59 ? 112 GLY A CA 1 ATOM 884 C C . GLY A 1 112 ? 4.805 73.660 10.712 1.00 19.31 ? 112 GLY A C 1 ATOM 885 O O . GLY A 1 112 ? 4.664 74.827 10.352 1.00 18.41 ? 112 GLY A O 1 ATOM 886 N N . ALA A 1 113 ? 4.086 73.097 11.682 1.00 18.71 ? 113 ALA A N 1 ATOM 887 C CA . ALA A 1 113 ? 3.065 73.811 12.453 1.00 18.71 ? 113 ALA A CA 1 ATOM 888 C C . ALA A 1 113 ? 2.631 72.950 13.634 1.00 18.71 ? 113 ALA A C 1 ATOM 889 O O . ALA A 1 113 ? 2.479 71.739 13.498 1.00 18.71 ? 113 ALA A O 1 ATOM 890 C CB . ALA A 1 113 ? 1.873 74.113 11.589 1.00 4.65 ? 113 ALA A CB 1 ATOM 891 N N . PHE A 1 114 ? 2.431 73.577 14.788 1.00 9.41 ? 114 PHE A N 1 ATOM 892 C CA . PHE A 1 114 ? 2.009 72.868 15.994 1.00 9.41 ? 114 PHE A CA 1 ATOM 893 C C . PHE A 1 114 ? 1.256 73.783 16.942 1.00 9.41 ? 114 PHE A C 1 ATOM 894 O O . PHE A 1 114 ? 1.521 74.980 17.025 1.00 9.41 ? 114 PHE A O 1 ATOM 895 C CB . PHE A 1 114 ? 3.220 72.247 16.718 1.00 33.89 ? 114 PHE A CB 1 ATOM 896 C CG . PHE A 1 114 ? 4.358 73.205 16.947 1.00 33.89 ? 114 PHE A CG 1 ATOM 897 C CD1 . PHE A 1 114 ? 4.337 74.099 18.014 1.00 33.89 ? 114 PHE A CD1 1 ATOM 898 C CD2 . PHE A 1 114 ? 5.445 73.234 16.073 1.00 33.89 ? 114 PHE A CD2 1 ATOM 899 C CE1 . PHE A 1 114 ? 5.386 75.012 18.208 1.00 33.89 ? 114 PHE A CE1 1 ATOM 900 C CE2 . PHE A 1 114 ? 6.491 74.137 16.256 1.00 33.89 ? 114 PHE A CE2 1 ATOM 901 C CZ . PHE A 1 114 ? 6.460 75.029 17.326 1.00 33.89 ? 114 PHE A CZ 1 ATOM 902 N N . TRP A 1 115 ? 0.304 73.203 17.653 1.00 14.02 ? 115 TRP A N 1 ATOM 903 C CA . TRP A 1 115 ? -0.513 73.941 18.593 1.00 14.02 ? 115 TRP A CA 1 ATOM 904 C C . TRP A 1 115 ? -1.080 72.861 19.494 1.00 14.02 ? 115 TRP A C 1 ATOM 905 O O . TRP A 1 115 ? -2.015 72.167 19.127 1.00 14.02 ? 115 TRP A O 1 ATOM 906 C CB . TRP A 1 115 ? -1.632 74.652 17.838 1.00 4.65 ? 115 TRP A CB 1 ATOM 907 C CG . TRP A 1 115 ? -2.363 75.692 18.617 1.00 4.65 ? 115 TRP A CG 1 ATOM 908 C CD1 . TRP A 1 115 ? -2.383 75.859 19.979 1.00 4.65 ? 115 TRP A CD1 1 ATOM 909 C CD2 . TRP A 1 115 ? -3.195 76.715 18.080 1.00 4.65 ? 115 TRP A CD2 1 ATOM 910 N NE1 . TRP A 1 115 ? -3.175 76.924 20.314 1.00 4.65 ? 115 TRP A NE1 1 ATOM 911 C CE2 . TRP A 1 115 ? -3.685 77.469 19.165 1.00 4.65 ? 115 TRP A CE2 1 ATOM 912 C CE3 . TRP A 1 115 ? -3.575 77.074 16.783 1.00 4.65 ? 115 TRP A CE3 1 ATOM 913 C CZ2 . TRP A 1 115 ? -4.537 78.560 18.986 1.00 4.65 ? 115 TRP A CZ2 1 ATOM 914 C CZ3 . TRP A 1 115 ? -4.420 78.163 16.611 1.00 4.65 ? 115 TRP A CZ3 1 ATOM 915 C CH2 . TRP A 1 115 ? -4.889 78.889 17.703 1.00 4.65 ? 115 TRP A CH2 1 ATOM 916 N N . LYS A 1 116 ? -0.499 72.709 20.671 1.00 7.98 ? 116 LYS A N 1 ATOM 917 C CA . LYS A 1 116 ? -0.934 71.688 21.604 1.00 7.98 ? 116 LYS A CA 1 ATOM 918 C C . LYS A 1 116 ? -0.939 72.211 23.046 1.00 7.98 ? 116 LYS A C 1 ATOM 919 O O . LYS A 1 116 ? -0.095 73.030 23.411 1.00 7.98 ? 116 LYS A O 1 ATOM 920 C CB . LYS A 1 116 ? 0.008 70.493 21.477 1.00 7.52 ? 116 LYS A CB 1 ATOM 921 C CG . LYS A 1 116 ? -0.408 69.252 22.240 1.00 7.52 ? 116 LYS A CG 1 ATOM 922 C CD . LYS A 1 116 ? 0.550 68.119 21.979 1.00 7.52 ? 116 LYS A CD 1 ATOM 923 C CE . LYS A 1 116 ? 0.138 66.893 22.728 1.00 7.52 ? 116 LYS A CE 1 ATOM 924 N NZ . LYS A 1 116 ? 1.043 65.749 22.420 1.00 7.52 ? 116 LYS A NZ 1 ATOM 925 N N . TYR A 1 117 ? -1.900 71.760 23.852 1.00 13.64 ? 117 TYR A N 1 ATOM 926 C CA . TYR A 1 117 ? -1.975 72.157 25.260 1.00 13.64 ? 117 TYR A CA 1 ATOM 927 C C . TYR A 1 117 ? -1.827 70.942 26.164 1.00 13.64 ? 117 TYR A C 1 ATOM 928 O O . TYR A 1 117 ? -2.324 69.862 25.860 1.00 13.64 ? 117 TYR A O 1 ATOM 929 C CB . TYR A 1 117 ? -3.307 72.833 25.594 1.00 4.65 ? 117 TYR A CB 1 ATOM 930 C CG . TYR A 1 117 ? -3.557 74.110 24.857 1.00 4.65 ? 117 TYR A CG 1 ATOM 931 C CD1 . TYR A 1 117 ? -3.989 74.099 23.549 1.00 4.65 ? 117 TYR A CD1 1 ATOM 932 C CD2 . TYR A 1 117 ? -3.307 75.335 25.455 1.00 4.65 ? 117 TYR A CD2 1 ATOM 933 C CE1 . TYR A 1 117 ? -4.161 75.284 22.855 1.00 4.65 ? 117 TYR A CE1 1 ATOM 934 C CE2 . TYR A 1 117 ? -3.473 76.513 24.771 1.00 4.65 ? 117 TYR A CE2 1 ATOM 935 C CZ . TYR A 1 117 ? -3.898 76.485 23.475 1.00 4.65 ? 117 TYR A CZ 1 ATOM 936 O OH . TYR A 1 117 ? -4.057 77.656 22.788 1.00 4.65 ? 117 TYR A OH 1 ATOM 937 N N . TYR A 1 118 ? -1.159 71.135 27.292 1.00 10.52 ? 118 TYR A N 1 ATOM 938 C CA . TYR A 1 118 ? -0.947 70.063 28.249 1.00 10.52 ? 118 TYR A CA 1 ATOM 939 C C . TYR A 1 118 ? -1.524 70.423 29.608 1.00 10.52 ? 118 TYR A C 1 ATOM 940 O O . TYR A 1 118 ? -1.343 71.541 30.083 1.00 10.52 ? 118 TYR A O 1 ATOM 941 C CB . TYR A 1 118 ? 0.546 69.781 28.382 1.00 4.65 ? 118 TYR A CB 1 ATOM 942 C CG . TYR A 1 118 ? 1.221 69.536 27.065 1.00 4.65 ? 118 TYR A CG 1 ATOM 943 C CD1 . TYR A 1 118 ? 1.654 70.597 26.268 1.00 4.65 ? 118 TYR A CD1 1 ATOM 944 C CD2 . TYR A 1 118 ? 1.437 68.239 26.607 1.00 4.65 ? 118 TYR A CD2 1 ATOM 945 C CE1 . TYR A 1 118 ? 2.298 70.358 25.045 1.00 4.65 ? 118 TYR A CE1 1 ATOM 946 C CE2 . TYR A 1 118 ? 2.071 67.996 25.394 1.00 4.65 ? 118 TYR A CE2 1 ATOM 947 C CZ . TYR A 1 118 ? 2.502 69.052 24.622 1.00 4.65 ? 118 TYR A CZ 1 ATOM 948 O OH . TYR A 1 118 ? 3.161 68.799 23.451 1.00 4.65 ? 118 TYR A OH 1 ATOM 949 N N . TYR A 1 119 ? -2.211 69.470 30.231 1.00 9.33 ? 119 TYR A N 1 ATOM 950 C CA . TYR A 1 119 ? -2.814 69.704 31.537 1.00 9.33 ? 119 TYR A CA 1 ATOM 951 C C . TYR A 1 119 ? -2.261 68.772 32.605 1.00 9.33 ? 119 TYR A C 1 ATOM 952 O O . TYR A 1 119 ? -2.493 67.573 32.581 1.00 9.33 ? 119 TYR A O 1 ATOM 953 C CB . TYR A 1 119 ? -4.311 69.526 31.448 1.00 10.15 ? 119 TYR A CB 1 ATOM 954 C CG . TYR A 1 119 ? -4.997 69.632 32.773 1.00 10.15 ? 119 TYR A CG 1 ATOM 955 C CD1 . TYR A 1 119 ? -5.144 70.853 33.401 1.00 10.15 ? 119 TYR A CD1 1 ATOM 956 C CD2 . TYR A 1 119 ? -5.514 68.507 33.394 1.00 10.15 ? 119 TYR A CD2 1 ATOM 957 C CE1 . TYR A 1 119 ? -5.796 70.951 34.620 1.00 10.15 ? 119 TYR A CE1 1 ATOM 958 C CE2 . TYR A 1 119 ? -6.161 68.592 34.608 1.00 10.15 ? 119 TYR A CE2 1 ATOM 959 C CZ . TYR A 1 119 ? -6.299 69.811 35.220 1.00 12.19 ? 119 TYR A CZ 1 ATOM 960 O OH . TYR A 1 119 ? -6.912 69.887 36.446 1.00 10.59 ? 119 TYR A OH 1 ATOM 961 N N . ASP A 1 120 ? -1.554 69.338 33.568 1.00 11.00 ? 120 ASP A N 1 ATOM 962 C CA . ASP A 1 120 ? -0.938 68.548 34.620 1.00 11.00 ? 120 ASP A CA 1 ATOM 963 C C . ASP A 1 120 ? 0.003 67.555 33.962 1.00 11.00 ? 120 ASP A C 1 ATOM 964 O O . ASP A 1 120 ? 0.195 66.443 34.443 1.00 11.00 ? 120 ASP A O 1 ATOM 965 C CB . ASP A 1 120 ? -1.985 67.826 35.482 1.00 18.32 ? 120 ASP A CB 1 ATOM 966 C CG . ASP A 1 120 ? -2.482 68.689 36.635 1.00 18.32 ? 120 ASP A CG 1 ATOM 967 O OD1 . ASP A 1 120 ? -1.786 69.658 36.973 1.00 18.32 ? 120 ASP A OD1 1 ATOM 968 O OD2 . ASP A 1 120 ? -3.550 68.407 37.212 1.00 18.32 ? 120 ASP A OD2 1 ATOM 969 N N . GLY A 1 121 ? 0.587 67.973 32.846 1.00 4.65 ? 121 GLY A N 1 ATOM 970 C CA . GLY A 1 121 ? 1.539 67.130 32.158 1.00 4.65 ? 121 GLY A CA 1 ATOM 971 C C . GLY A 1 121 ? 0.976 66.219 31.101 1.00 4.65 ? 121 GLY A C 1 ATOM 972 O O . GLY A 1 121 ? 1.708 65.774 30.223 1.00 4.65 ? 121 GLY A O 1 ATOM 973 N N . LYS A 1 122 ? -0.314 65.927 31.177 1.00 6.62 ? 122 LYS A N 1 ATOM 974 C CA . LYS A 1 122 ? -0.922 65.052 30.197 1.00 6.62 ? 122 LYS A CA 1 ATOM 975 C C . LYS A 1 122 ? -1.365 65.846 28.976 1.00 6.62 ? 122 LYS A C 1 ATOM 976 O O . LYS A 1 122 ? -1.628 67.054 29.062 1.00 6.62 ? 122 LYS A O 1 ATOM 977 C CB . LYS A 1 122 ? -2.137 64.320 30.779 1.00 42.31 ? 122 LYS A CB 1 ATOM 978 C CG . LYS A 1 122 ? -1.862 63.406 31.955 1.00 44.94 ? 122 LYS A CG 1 ATOM 979 C CD . LYS A 1 122 ? -2.042 64.148 33.276 1.00 76.90 ? 122 LYS A CD 1 ATOM 980 C CE . LYS A 1 122 ? -1.849 63.229 34.482 1.00 87.31 ? 122 LYS A CE 1 ATOM 981 N NZ . LYS A 1 122 ? -1.885 63.976 35.780 1.00 73.16 ? 122 LYS A NZ 1 ATOM 982 N N . ASP A 1 123 ? -1.438 65.153 27.838 1.00 10.34 ? 123 ASP A N 1 ATOM 983 C CA . ASP A 1 123 ? -1.883 65.767 26.602 1.00 10.34 ? 123 ASP A CA 1 ATOM 984 C C . ASP A 1 123 ? -3.306 66.180 26.870 1.00 10.34 ? 123 ASP A C 1 ATOM 985 O O . ASP A 1 123 ? -4.081 65.397 27.394 1.00 10.34 ? 123 ASP A O 1 ATOM 986 C CB . ASP A 1 123 ? -1.871 64.769 25.450 1.00 22.51 ? 123 ASP A CB 1 ATOM 987 C CG . ASP A 1 123 ? -0.477 64.376 25.023 1.00 22.51 ? 123 ASP A CG 1 ATOM 988 O OD1 . ASP A 1 123 ? 0.467 65.160 25.243 1.00 22.51 ? 123 ASP A OD1 1 ATOM 989 O OD2 . ASP A 1 123 ? -0.331 63.286 24.440 1.00 22.51 ? 123 ASP A OD2 1 ATOM 990 N N . TYR A 1 124 ? -3.656 67.405 26.519 1.00 8.12 ? 124 TYR A N 1 ATOM 991 C CA . TYR A 1 124 ? -5.004 67.865 26.765 1.00 8.12 ? 124 TYR A CA 1 ATOM 992 C C . TYR A 1 124 ? -5.828 68.030 25.497 1.00 8.12 ? 124 TYR A C 1 ATOM 993 O O . TYR A 1 124 ? -6.874 67.408 25.348 1.00 8.12 ? 124 TYR A O 1 ATOM 994 C CB . TYR A 1 124 ? -4.967 69.187 27.530 1.00 9.85 ? 124 TYR A CB 1 ATOM 995 C CG . TYR A 1 124 ? -6.329 69.710 27.896 1.00 9.85 ? 124 TYR A CG 1 ATOM 996 C CD1 . TYR A 1 124 ? -7.126 69.050 28.823 1.00 9.85 ? 124 TYR A CD1 1 ATOM 997 C CD2 . TYR A 1 124 ? -6.839 70.836 27.279 1.00 9.85 ? 124 TYR A CD2 1 ATOM 998 C CE1 . TYR A 1 124 ? -8.408 69.500 29.119 1.00 9.85 ? 124 TYR A CE1 1 ATOM 999 C CE2 . TYR A 1 124 ? -8.112 71.293 27.565 1.00 9.85 ? 124 TYR A CE2 1 ATOM 1000 C CZ . TYR A 1 124 ? -8.890 70.624 28.482 1.00 9.85 ? 124 TYR A CZ 1 ATOM 1001 O OH . TYR A 1 124 ? -10.147 71.097 28.746 1.00 9.85 ? 124 TYR A OH 1 ATOM 1002 N N . ILE A 1 125 ? -5.362 68.887 24.596 1.00 4.65 ? 125 ILE A N 1 ATOM 1003 C CA . ILE A 1 125 ? -6.069 69.141 23.350 1.00 4.65 ? 125 ILE A CA 1 ATOM 1004 C C . ILE A 1 125 ? -5.040 69.689 22.381 1.00 4.65 ? 125 ILE A C 1 ATOM 1005 O O . ILE A 1 125 ? -4.084 70.332 22.789 1.00 4.65 ? 125 ILE A O 1 ATOM 1006 C CB . ILE A 1 125 ? -7.240 70.165 23.562 1.00 6.48 ? 125 ILE A CB 1 ATOM 1007 C CG1 . ILE A 1 125 ? -8.311 69.972 22.493 1.00 6.48 ? 125 ILE A CG1 1 ATOM 1008 C CG2 . ILE A 1 125 ? -6.728 71.599 23.520 1.00 6.48 ? 125 ILE A CG2 1 ATOM 1009 C CD1 . ILE A 1 125 ? -9.439 71.018 22.534 1.00 6.48 ? 125 ILE A CD1 1 ATOM 1010 N N . GLU A 1 126 ? -5.213 69.406 21.099 1.00 15.10 ? 126 GLU A N 1 ATOM 1011 C CA . GLU A 1 126 ? -4.280 69.886 20.091 1.00 15.10 ? 126 GLU A CA 1 ATOM 1012 C C . GLU A 1 126 ? -5.067 70.143 18.819 1.00 15.10 ? 126 GLU A C 1 ATOM 1013 O O . GLU A 1 126 ? -6.077 69.486 18.570 1.00 15.10 ? 126 GLU A O 1 ATOM 1014 C CB . GLU A 1 126 ? -3.198 68.843 19.817 1.00 21.59 ? 126 GLU A CB 1 ATOM 1015 C CG . GLU A 1 126 ? -3.711 67.673 19.035 1.00 21.59 ? 126 GLU A CG 1 ATOM 1016 C CD . GLU A 1 126 ? -2.623 66.765 18.522 1.00 26.21 ? 126 GLU A CD 1 ATOM 1017 O OE1 . GLU A 1 126 ? -2.943 65.923 17.649 1.00 21.59 ? 126 GLU A OE1 1 ATOM 1018 O OE2 . GLU A 1 126 ? -1.463 66.878 18.985 1.00 21.59 ? 126 GLU A OE2 1 ATOM 1019 N N . PHE A 1 127 ? -4.608 71.084 18.007 1.00 15.97 ? 127 PHE A N 1 ATOM 1020 C CA . PHE A 1 127 ? -5.311 71.395 16.766 1.00 15.97 ? 127 PHE A CA 1 ATOM 1021 C C . PHE A 1 127 ? -4.720 70.694 15.530 1.00 15.97 ? 127 PHE A C 1 ATOM 1022 O O . PHE A 1 127 ? -3.494 70.629 15.360 1.00 15.97 ? 127 PHE A O 1 ATOM 1023 C CB . PHE A 1 127 ? -5.311 72.906 16.564 1.00 7.36 ? 127 PHE A CB 1 ATOM 1024 C CG . PHE A 1 127 ? -6.047 73.361 15.351 1.00 7.36 ? 127 PHE A CG 1 ATOM 1025 C CD1 . PHE A 1 127 ? -7.424 73.375 15.330 1.00 7.36 ? 127 PHE A CD1 1 ATOM 1026 C CD2 . PHE A 1 127 ? -5.356 73.819 14.244 1.00 7.36 ? 127 PHE A CD2 1 ATOM 1027 C CE1 . PHE A 1 127 ? -8.106 73.844 14.227 1.00 7.36 ? 127 PHE A CE1 1 ATOM 1028 C CE2 . PHE A 1 127 ? -6.029 74.286 13.142 1.00 7.36 ? 127 PHE A CE2 1 ATOM 1029 C CZ . PHE A 1 127 ? -7.406 74.302 13.132 1.00 7.36 ? 127 PHE A CZ 1 ATOM 1030 N N . ASN A 1 128 ? -5.601 70.169 14.681 1.00 10.91 ? 128 ASN A N 1 ATOM 1031 C CA . ASN A 1 128 ? -5.210 69.479 13.453 1.00 10.91 ? 128 ASN A CA 1 ATOM 1032 C C . ASN A 1 128 ? -5.703 70.335 12.285 1.00 10.91 ? 128 ASN A C 1 ATOM 1033 O O . ASN A 1 128 ? -6.864 70.245 11.883 1.00 10.91 ? 128 ASN A O 1 ATOM 1034 C CB . ASN A 1 128 ? -5.871 68.103 13.420 1.00 13.04 ? 128 ASN A CB 1 ATOM 1035 C CG . ASN A 1 128 ? -5.440 67.265 12.232 1.00 13.04 ? 128 ASN A CG 1 ATOM 1036 O OD1 . ASN A 1 128 ? -5.343 67.758 11.120 1.00 13.04 ? 128 ASN A OD1 1 ATOM 1037 N ND2 . ASN A 1 128 ? -5.203 65.984 12.467 1.00 13.04 ? 128 ASN A ND2 1 ATOM 1038 N N . LYS A 1 129 ? -4.825 71.169 11.740 1.00 11.67 ? 129 LYS A N 1 ATOM 1039 C CA . LYS A 1 129 ? -5.207 72.057 10.652 1.00 11.67 ? 129 LYS A CA 1 ATOM 1040 C C . LYS A 1 129 ? -5.635 71.369 9.364 1.00 11.67 ? 129 LYS A C 1 ATOM 1041 O O . LYS A 1 129 ? -6.029 72.039 8.417 1.00 11.67 ? 129 LYS A O 1 ATOM 1042 C CB . LYS A 1 129 ? -4.074 73.020 10.337 1.00 20.80 ? 129 LYS A CB 1 ATOM 1043 C CG . LYS A 1 129 ? -2.862 72.326 9.783 1.00 20.80 ? 129 LYS A CG 1 ATOM 1044 C CD . LYS A 1 129 ? -1.775 73.302 9.349 1.00 20.80 ? 129 LYS A CD 1 ATOM 1045 C CE . LYS A 1 129 ? -0.640 72.567 8.644 1.00 23.43 ? 129 LYS A CE 1 ATOM 1046 N NZ . LYS A 1 129 ? -1.189 71.649 7.592 1.00 29.57 ? 129 LYS A NZ 1 ATOM 1047 N N . GLU A 1 130 ? -5.574 70.044 9.306 1.00 19.29 ? 130 GLU A N 1 ATOM 1048 C CA . GLU A 1 130 ? -5.976 69.363 8.085 1.00 19.29 ? 130 GLU A CA 1 ATOM 1049 C C . GLU A 1 130 ? -7.453 69.024 8.046 1.00 19.29 ? 130 GLU A C 1 ATOM 1050 O O . GLU A 1 130 ? -8.071 69.012 6.980 1.00 19.29 ? 130 GLU A O 1 ATOM 1051 C CB . GLU A 1 130 ? -5.193 68.080 7.888 1.00 9.15 ? 130 GLU A CB 1 ATOM 1052 C CG . GLU A 1 130 ? -5.466 67.467 6.540 1.00 10.99 ? 130 GLU A CG 1 ATOM 1053 C CD . GLU A 1 130 ? -4.728 66.182 6.320 1.00 17.00 ? 130 GLU A CD 1 ATOM 1054 O OE1 . GLU A 1 130 ? -5.124 65.174 6.913 1.00 9.15 ? 130 GLU A OE1 1 ATOM 1055 O OE2 . GLU A 1 130 ? -3.749 66.171 5.558 1.00 9.15 ? 130 GLU A OE2 1 ATOM 1056 N N . ILE A 1 131 ? -8.026 68.742 9.208 1.00 10.53 ? 131 ILE A N 1 ATOM 1057 C CA . ILE A 1 131 ? -9.420 68.386 9.251 1.00 10.53 ? 131 ILE A CA 1 ATOM 1058 C C . ILE A 1 131 ? -10.347 69.493 8.755 1.00 10.53 ? 131 ILE A C 1 ATOM 1059 O O . ILE A 1 131 ? -11.077 69.276 7.804 1.00 10.53 ? 131 ILE A O 1 ATOM 1060 C CB . ILE A 1 131 ? -9.819 67.925 10.645 1.00 14.93 ? 131 ILE A CB 1 ATOM 1061 C CG1 . ILE A 1 131 ? -9.034 66.663 10.995 1.00 14.93 ? 131 ILE A CG1 1 ATOM 1062 C CG2 . ILE A 1 131 ? -11.305 67.646 10.688 1.00 14.93 ? 131 ILE A CG2 1 ATOM 1063 C CD1 . ILE A 1 131 ? -9.443 66.020 12.299 1.00 14.93 ? 131 ILE A CD1 1 ATOM 1064 N N . PRO A 1 132 ? -10.352 70.690 9.380 1.00 12.89 ? 132 PRO A N 1 ATOM 1065 C CA . PRO A 1 132 ? -9.621 71.228 10.525 1.00 12.89 ? 132 PRO A CA 1 ATOM 1066 C C . PRO A 1 132 ? -10.487 71.180 11.776 1.00 12.89 ? 132 PRO A C 1 ATOM 1067 O O . PRO A 1 132 ? -11.689 71.448 11.728 1.00 12.89 ? 132 PRO A O 1 ATOM 1068 C CB . PRO A 1 132 ? -9.345 72.652 10.091 1.00 5.75 ? 132 PRO A CB 1 ATOM 1069 C CG . PRO A 1 132 ? -10.595 73.005 9.458 1.00 5.75 ? 132 PRO A CG 1 ATOM 1070 C CD . PRO A 1 132 ? -10.928 71.806 8.609 1.00 5.75 ? 132 PRO A CD 1 ATOM 1071 N N . ALA A 1 133 ? -9.875 70.841 12.899 1.00 17.36 ? 133 ALA A N 1 ATOM 1072 C CA . ALA A 1 133 ? -10.613 70.767 14.142 1.00 17.36 ? 133 ALA A CA 1 ATOM 1073 C C . ALA A 1 133 ? -9.671 70.473 15.266 1.00 17.36 ? 133 ALA A C 1 ATOM 1074 O O . ALA A 1 133 ? -8.521 70.123 15.040 1.00 17.36 ? 133 ALA A O 1 ATOM 1075 C CB . ALA A 1 133 ? -11.640 69.686 14.063 1.00 6.07 ? 133 ALA A CB 1 ATOM 1076 N N . TRP A 1 134 ? -10.165 70.624 16.484 1.00 4.65 ? 134 TRP A N 1 ATOM 1077 C CA . TRP A 1 134 ? -9.359 70.339 17.647 1.00 4.65 ? 134 TRP A CA 1 ATOM 1078 C C . TRP A 1 134 ? -9.600 68.878 17.999 1.00 4.65 ? 134 TRP A C 1 ATOM 1079 O O . TRP A 1 134 ? -10.687 68.349 17.817 1.00 4.65 ? 134 TRP A O 1 ATOM 1080 C CB . TRP A 1 134 ? -9.747 71.244 18.821 1.00 7.14 ? 134 TRP A CB 1 ATOM 1081 C CG . TRP A 1 134 ? -9.408 72.677 18.615 1.00 7.14 ? 134 TRP A CG 1 ATOM 1082 C CD1 . TRP A 1 134 ? -10.176 73.622 17.998 1.00 7.14 ? 134 TRP A CD1 1 ATOM 1083 C CD2 . TRP A 1 134 ? -8.191 73.329 18.979 1.00 7.14 ? 134 TRP A CD2 1 ATOM 1084 N NE1 . TRP A 1 134 ? -9.511 74.823 17.954 1.00 7.14 ? 134 TRP A NE1 1 ATOM 1085 C CE2 . TRP A 1 134 ? -8.288 74.669 18.547 1.00 7.14 ? 134 TRP A CE2 1 ATOM 1086 C CE3 . TRP A 1 134 ? -7.024 72.912 19.625 1.00 7.14 ? 134 TRP A CE3 1 ATOM 1087 C CZ2 . TRP A 1 134 ? -7.261 75.594 18.738 1.00 7.14 ? 134 TRP A CZ2 1 ATOM 1088 C CZ3 . TRP A 1 134 ? -5.998 73.834 19.816 1.00 7.14 ? 134 TRP A CZ3 1 ATOM 1089 C CH2 . TRP A 1 134 ? -6.126 75.161 19.372 1.00 7.14 ? 134 TRP A CH2 1 ATOM 1090 N N . VAL A 1 135 ? -8.558 68.215 18.462 1.00 4.65 ? 135 VAL A N 1 ATOM 1091 C CA . VAL A 1 135 ? -8.670 66.831 18.863 1.00 4.65 ? 135 VAL A CA 1 ATOM 1092 C C . VAL A 1 135 ? -8.586 66.869 20.376 1.00 4.65 ? 135 VAL A C 1 ATOM 1093 O O . VAL A 1 135 ? -7.642 67.413 20.938 1.00 4.65 ? 135 VAL A O 1 ATOM 1094 C CB . VAL A 1 135 ? -7.510 65.985 18.308 1.00 4.65 ? 135 VAL A CB 1 ATOM 1095 C CG1 . VAL A 1 135 ? -7.650 64.561 18.756 1.00 4.65 ? 135 VAL A CG1 1 ATOM 1096 C CG2 . VAL A 1 135 ? -7.489 66.062 16.803 1.00 4.65 ? 135 VAL A CG2 1 ATOM 1097 N N . PRO A 1 136 ? -9.601 66.333 21.058 1.00 18.99 ? 136 PRO A N 1 ATOM 1098 C CA . PRO A 1 136 ? -9.569 66.336 22.518 1.00 18.99 ? 136 PRO A CA 1 ATOM 1099 C C . PRO A 1 136 ? -8.987 65.023 23.004 1.00 18.99 ? 136 PRO A C 1 ATOM 1100 O O . PRO A 1 136 ? -9.294 63.982 22.458 1.00 18.99 ? 136 PRO A O 1 ATOM 1101 C CB . PRO A 1 136 ? -11.034 66.488 22.881 1.00 4.65 ? 136 PRO A CB 1 ATOM 1102 C CG . PRO A 1 136 ? -11.699 65.669 21.822 1.00 4.65 ? 136 PRO A CG 1 ATOM 1103 C CD . PRO A 1 136 ? -10.942 65.980 20.557 1.00 4.65 ? 136 PRO A CD 1 ATOM 1104 N N . PHE A 1 137 ? -8.128 65.075 24.010 1.00 13.90 ? 137 PHE A N 1 ATOM 1105 C CA . PHE A 1 137 ? -7.534 63.867 24.566 1.00 13.90 ? 137 PHE A CA 1 ATOM 1106 C C . PHE A 1 137 ? -7.982 63.652 26.013 1.00 13.90 ? 137 PHE A C 1 ATOM 1107 O O . PHE A 1 137 ? -7.785 62.588 26.585 1.00 28.67 ? 137 PHE A O 1 ATOM 1108 C CB . PHE A 1 137 ? -6.025 63.955 24.528 1.00 4.65 ? 137 PHE A CB 1 ATOM 1109 C CG . PHE A 1 137 ? -5.465 64.158 23.163 1.00 4.65 ? 137 PHE A CG 1 ATOM 1110 C CD1 . PHE A 1 137 ? -5.620 63.197 22.189 1.00 4.65 ? 137 PHE A CD1 1 ATOM 1111 C CD2 . PHE A 1 137 ? -4.731 65.311 22.862 1.00 4.65 ? 137 PHE A CD2 1 ATOM 1112 C CE1 . PHE A 1 137 ? -5.052 63.368 20.929 1.00 4.65 ? 137 PHE A CE1 1 ATOM 1113 C CE2 . PHE A 1 137 ? -4.161 65.490 21.606 1.00 4.65 ? 137 PHE A CE2 1 ATOM 1114 C CZ . PHE A 1 137 ? -4.324 64.512 20.640 1.00 4.65 ? 137 PHE A CZ 1 ATOM 1115 N N . ASP A 1 138 ? -8.592 64.672 26.595 1.00 13.16 ? 138 ASP A N 1 ATOM 1116 C CA . ASP A 1 138 ? -9.061 64.595 27.965 1.00 13.16 ? 138 ASP A CA 1 ATOM 1117 C C . ASP A 1 138 ? -10.566 64.868 28.009 1.00 13.16 ? 138 ASP A C 1 ATOM 1118 O O . ASP A 1 138 ? -11.081 65.699 27.260 1.00 13.16 ? 138 ASP A O 1 ATOM 1119 C CB . ASP A 1 138 ? -8.300 65.617 28.809 1.00 23.02 ? 138 ASP A CB 1 ATOM 1120 C CG . ASP A 1 138 ? -8.675 65.575 30.272 1.00 23.09 ? 138 ASP A CG 1 ATOM 1121 O OD1 . ASP A 1 138 ? -9.849 65.823 30.601 1.00 23.02 ? 138 ASP A OD1 1 ATOM 1122 O OD2 . ASP A 1 138 ? -7.782 65.304 31.097 1.00 23.02 ? 138 ASP A OD2 1 ATOM 1123 N N . PRO A 1 139 ? -11.296 64.156 28.881 1.00 12.81 ? 139 PRO A N 1 ATOM 1124 C CA . PRO A 1 139 ? -12.736 64.374 28.972 1.00 12.81 ? 139 PRO A CA 1 ATOM 1125 C C . PRO A 1 139 ? -13.162 65.842 29.094 1.00 12.81 ? 139 PRO A C 1 ATOM 1126 O O . PRO A 1 139 ? -14.213 66.232 28.607 1.00 12.81 ? 139 PRO A O 1 ATOM 1127 C CB . PRO A 1 139 ? -13.138 63.526 30.182 1.00 6.70 ? 139 PRO A CB 1 ATOM 1128 C CG . PRO A 1 139 ? -11.845 63.258 30.902 1.00 16.85 ? 139 PRO A CG 1 ATOM 1129 C CD . PRO A 1 139 ? -10.880 63.082 29.791 1.00 9.51 ? 139 PRO A CD 1 ATOM 1130 N N . ALA A 1 140 ? -12.356 66.666 29.739 1.00 17.64 ? 140 ALA A N 1 ATOM 1131 C CA . ALA A 1 140 ? -12.725 68.059 29.868 1.00 17.64 ? 140 ALA A CA 1 ATOM 1132 C C . ALA A 1 140 ? -12.354 68.784 28.588 1.00 17.64 ? 140 ALA A C 1 ATOM 1133 O O . ALA A 1 140 ? -12.861 69.872 28.314 1.00 17.64 ? 140 ALA A O 1 ATOM 1134 C CB . ALA A 1 140 ? -12.018 68.680 31.046 1.00 20.86 ? 140 ALA A CB 1 ATOM 1135 N N . ALA A 1 141 ? -11.464 68.191 27.799 1.00 13.70 ? 141 ALA A N 1 ATOM 1136 C CA . ALA A 1 141 ? -11.059 68.828 26.555 1.00 13.70 ? 141 ALA A CA 1 ATOM 1137 C C . ALA A 1 141 ? -12.283 68.909 25.661 1.00 13.70 ? 141 ALA A C 1 ATOM 1138 O O . ALA A 1 141 ? -12.374 69.777 24.793 1.00 13.70 ? 141 ALA A O 1 ATOM 1139 C CB . ALA A 1 141 ? -9.958 68.031 25.881 1.00 18.41 ? 141 ALA A CB 1 ATOM 1140 N N . GLN A 1 142 ? -13.229 68.003 25.902 1.00 12.95 ? 142 GLN A N 1 ATOM 1141 C CA . GLN A 1 142 ? -14.465 67.949 25.140 1.00 12.95 ? 142 GLN A CA 1 ATOM 1142 C C . GLN A 1 142 ? -15.254 69.244 25.237 1.00 12.95 ? 142 GLN A C 1 ATOM 1143 O O . GLN A 1 142 ? -15.800 69.716 24.245 1.00 12.95 ? 142 GLN A O 1 ATOM 1144 C CB . GLN A 1 142 ? -15.316 66.773 25.602 1.00 14.34 ? 142 GLN A CB 1 ATOM 1145 C CG . GLN A 1 142 ? -14.742 65.448 25.150 1.00 14.34 ? 142 GLN A CG 1 ATOM 1146 C CD . GLN A 1 142 ? -15.626 64.267 25.476 1.00 14.34 ? 142 GLN A CD 1 ATOM 1147 O OE1 . GLN A 1 142 ? -16.849 64.360 25.447 1.00 14.34 ? 142 GLN A OE1 1 ATOM 1148 N NE2 . GLN A 1 142 ? -15.007 63.139 25.768 1.00 14.34 ? 142 GLN A NE2 1 ATOM 1149 N N . ILE A 1 143 ? -15.309 69.831 26.425 1.00 8.71 ? 143 ILE A N 1 ATOM 1150 C CA . ILE A 1 143 ? -16.028 71.079 26.591 1.00 8.71 ? 143 ILE A CA 1 ATOM 1151 C C . ILE A 1 143 ? -15.233 72.204 25.926 1.00 8.71 ? 143 ILE A C 1 ATOM 1152 O O . ILE A 1 143 ? -15.780 73.018 25.196 1.00 8.71 ? 143 ILE A O 1 ATOM 1153 C CB . ILE A 1 143 ? -16.193 71.458 28.059 1.00 15.28 ? 143 ILE A CB 1 ATOM 1154 C CG1 . ILE A 1 143 ? -16.761 70.287 28.865 1.00 16.34 ? 143 ILE A CG1 1 ATOM 1155 C CG2 . ILE A 1 143 ? -17.052 72.701 28.145 1.00 15.28 ? 143 ILE A CG2 1 ATOM 1156 C CD1 . ILE A 1 143 ? -18.157 69.945 28.534 1.00 30.07 ? 143 ILE A CD1 1 ATOM 1157 N N . THR A 1 144 ? -13.938 72.261 26.198 1.00 10.43 ? 144 THR A N 1 ATOM 1158 C CA . THR A 1 144 ? -13.097 73.288 25.614 1.00 10.43 ? 144 THR A CA 1 ATOM 1159 C C . THR A 1 144 ? -13.264 73.300 24.100 1.00 10.43 ? 144 THR A C 1 ATOM 1160 O O . THR A 1 144 ? -13.412 74.355 23.496 1.00 10.43 ? 144 THR A O 1 ATOM 1161 C CB . THR A 1 144 ? -11.622 73.037 25.951 1.00 10.35 ? 144 THR A CB 1 ATOM 1162 O OG1 . THR A 1 144 ? -11.465 72.976 27.372 1.00 10.35 ? 144 THR A OG1 1 ATOM 1163 C CG2 . THR A 1 144 ? -10.753 74.144 25.408 1.00 10.35 ? 144 THR A CG2 1 ATOM 1164 N N . LYS A 1 145 ? -13.238 72.120 23.487 1.00 15.51 ? 145 LYS A N 1 ATOM 1165 C CA . LYS A 1 145 ? -13.381 72.021 22.038 1.00 15.51 ? 145 LYS A CA 1 ATOM 1166 C C . LYS A 1 145 ? -14.716 72.615 21.641 1.00 15.51 ? 145 LYS A C 1 ATOM 1167 O O . LYS A 1 145 ? -14.821 73.337 20.660 1.00 15.51 ? 145 LYS A O 1 ATOM 1168 C CB . LYS A 1 145 ? -13.308 70.559 21.597 1.00 6.37 ? 145 LYS A CB 1 ATOM 1169 C CG . LYS A 1 145 ? -13.570 70.315 20.113 1.00 6.37 ? 145 LYS A CG 1 ATOM 1170 C CD . LYS A 1 145 ? -13.369 68.830 19.771 1.00 6.37 ? 145 LYS A CD 1 ATOM 1171 C CE . LYS A 1 145 ? -14.054 68.438 18.476 1.00 6.37 ? 145 LYS A CE 1 ATOM 1172 N NZ . LYS A 1 145 ? -13.636 69.278 17.338 1.00 6.37 ? 145 LYS A NZ 1 ATOM 1173 N N . GLN A 1 146 ? -15.734 72.307 22.432 1.00 24.20 ? 146 GLN A N 1 ATOM 1174 C CA . GLN A 1 146 ? -17.089 72.788 22.199 1.00 24.20 ? 146 GLN A CA 1 ATOM 1175 C C . GLN A 1 146 ? -17.094 74.309 22.138 1.00 24.20 ? 146 GLN A C 1 ATOM 1176 O O . GLN A 1 146 ? -17.651 74.894 21.220 1.00 24.20 ? 146 GLN A O 1 ATOM 1177 C CB . GLN A 1 146 ? -17.993 72.319 23.340 1.00 32.22 ? 146 GLN A CB 1 ATOM 1178 C CG . GLN A 1 146 ? -19.459 72.565 23.139 1.00 51.09 ? 146 GLN A CG 1 ATOM 1179 C CD . GLN A 1 146 ? -20.180 71.329 22.650 1.00 64.67 ? 146 GLN A CD 1 ATOM 1180 O OE1 . GLN A 1 146 ? -19.949 70.856 21.533 1.00 54.88 ? 146 GLN A OE1 1 ATOM 1181 N NE2 . GLN A 1 146 ? -21.056 70.787 23.493 1.00 59.38 ? 146 GLN A NE2 1 ATOM 1182 N N . LYS A 1 147 ? -16.462 74.936 23.124 1.00 11.49 ? 147 LYS A N 1 ATOM 1183 C CA . LYS A 1 147 ? -16.404 76.384 23.218 1.00 11.49 ? 147 LYS A CA 1 ATOM 1184 C C . LYS A 1 147 ? -15.591 77.048 22.130 1.00 11.49 ? 147 LYS A C 1 ATOM 1185 O O . LYS A 1 147 ? -15.968 78.110 21.627 1.00 11.49 ? 147 LYS A O 1 ATOM 1186 C CB . LYS A 1 147 ? -15.819 76.807 24.565 1.00 18.51 ? 147 LYS A CB 1 ATOM 1187 C CG . LYS A 1 147 ? -16.722 76.553 25.747 1.00 23.05 ? 147 LYS A CG 1 ATOM 1188 C CD . LYS A 1 147 ? -16.202 77.248 26.987 1.00 31.23 ? 147 LYS A CD 1 ATOM 1189 C CE . LYS A 1 147 ? -17.033 76.872 28.193 1.00 29.71 ? 147 LYS A CE 1 ATOM 1190 N NZ . LYS A 1 147 ? -16.470 77.467 29.431 1.00 45.36 ? 147 LYS A NZ 1 ATOM 1191 N N . TRP A 1 148 ? -14.459 76.433 21.800 1.00 22.64 ? 148 TRP A N 1 ATOM 1192 C CA . TRP A 1 148 ? -13.547 76.953 20.791 1.00 22.64 ? 148 TRP A CA 1 ATOM 1193 C C . TRP A 1 148 ? -14.030 76.679 19.385 1.00 22.64 ? 148 TRP A C 1 ATOM 1194 O O . TRP A 1 148 ? -13.340 77.009 18.424 1.00 22.64 ? 148 TRP A O 1 ATOM 1195 C CB . TRP A 1 148 ? -12.163 76.337 20.949 1.00 5.37 ? 148 TRP A CB 1 ATOM 1196 C CG . TRP A 1 148 ? -11.428 76.695 22.197 1.00 5.37 ? 148 TRP A CG 1 ATOM 1197 C CD1 . TRP A 1 148 ? -11.842 77.522 23.209 1.00 5.37 ? 148 TRP A CD1 1 ATOM 1198 C CD2 . TRP A 1 148 ? -10.129 76.235 22.563 1.00 5.37 ? 148 TRP A CD2 1 ATOM 1199 N NE1 . TRP A 1 148 ? -10.872 77.602 24.185 1.00 5.37 ? 148 TRP A NE1 1 ATOM 1200 C CE2 . TRP A 1 148 ? -9.811 76.820 23.811 1.00 5.37 ? 148 TRP A CE2 1 ATOM 1201 C CE3 . TRP A 1 148 ? -9.195 75.384 21.954 1.00 5.37 ? 148 TRP A CE3 1 ATOM 1202 C CZ2 . TRP A 1 148 ? -8.602 76.578 24.456 1.00 5.37 ? 148 TRP A CZ2 1 ATOM 1203 C CZ3 . TRP A 1 148 ? -7.992 75.149 22.599 1.00 5.37 ? 148 TRP A CZ3 1 ATOM 1204 C CH2 . TRP A 1 148 ? -7.709 75.743 23.835 1.00 5.37 ? 148 TRP A CH2 1 ATOM 1205 N N . GLU A 1 149 ? -15.199 76.060 19.263 1.00 13.23 ? 149 GLU A N 1 ATOM 1206 C CA . GLU A 1 149 ? -15.763 75.775 17.953 1.00 13.23 ? 149 GLU A CA 1 ATOM 1207 C C . GLU A 1 149 ? -17.236 76.151 17.890 1.00 13.23 ? 149 GLU A C 1 ATOM 1208 O O . GLU A 1 149 ? -17.983 75.628 17.071 1.00 13.23 ? 149 GLU A O 1 ATOM 1209 C CB . GLU A 1 149 ? -15.587 74.297 17.601 1.00 16.46 ? 149 GLU A CB 1 ATOM 1210 C CG . GLU A 1 149 ? -14.140 73.874 17.443 1.00 16.46 ? 149 GLU A CG 1 ATOM 1211 C CD . GLU A 1 149 ? -14.008 72.408 17.091 1.00 16.46 ? 149 GLU A CD 1 ATOM 1212 O OE1 . GLU A 1 149 ? -14.992 71.666 17.298 1.00 16.46 ? 149 GLU A OE1 1 ATOM 1213 O OE2 . GLU A 1 149 ? -12.926 71.993 16.624 1.00 16.46 ? 149 GLU A OE2 1 ATOM 1214 N N . ALA A 1 150 ? -17.652 77.080 18.737 1.00 12.90 ? 150 ALA A N 1 ATOM 1215 C CA . ALA A 1 150 ? -19.044 77.477 18.760 1.00 12.90 ? 150 ALA A CA 1 ATOM 1216 C C . ALA A 1 150 ? -19.475 78.167 17.487 1.00 12.90 ? 150 ALA A C 1 ATOM 1217 O O . ALA A 1 150 ? -20.646 78.145 17.149 1.00 13.11 ? 150 ALA A O 1 ATOM 1218 C CB . ALA A 1 150 ? -19.307 78.360 19.931 1.00 20.98 ? 150 ALA A CB 1 ATOM 1219 N N . GLU A 1 151 ? -18.540 78.779 16.776 1.00 19.12 ? 151 GLU A N 1 ATOM 1220 C CA . GLU A 1 151 ? -18.855 79.464 15.528 1.00 19.12 ? 151 GLU A CA 1 ATOM 1221 C C . GLU A 1 151 ? -17.993 78.925 14.367 1.00 19.12 ? 151 GLU A C 1 ATOM 1222 O O . GLU A 1 151 ? -16.785 78.734 14.507 1.00 19.12 ? 151 GLU A O 1 ATOM 1223 C CB . GLU A 1 151 ? -18.622 80.969 15.686 1.00 26.56 ? 151 GLU A CB 1 ATOM 1224 C CG . GLU A 1 151 ? -19.396 81.650 16.803 1.00 39.53 ? 151 GLU A CG 1 ATOM 1225 C CD . GLU A 1 151 ? -20.908 81.588 16.628 1.00 53.33 ? 151 GLU A CD 1 ATOM 1226 O OE1 . GLU A 1 151 ? -21.373 81.529 15.469 1.00 45.81 ? 151 GLU A OE1 1 ATOM 1227 O OE2 . GLU A 1 151 ? -21.634 81.619 17.652 1.00 58.53 ? 151 GLU A OE2 1 ATOM 1228 N N . PRO A 1 152 ? -18.608 78.669 13.204 1.00 18.71 ? 152 PRO A N 1 ATOM 1229 C CA . PRO A 1 152 ? -17.916 78.158 12.023 1.00 22.66 ? 152 PRO A CA 1 ATOM 1230 C C . PRO A 1 152 ? -16.615 78.886 11.723 1.00 18.71 ? 152 PRO A C 1 ATOM 1231 O O . PRO A 1 152 ? -15.701 78.314 11.129 1.00 18.71 ? 152 PRO A O 1 ATOM 1232 C CB . PRO A 1 152 ? -18.936 78.374 10.924 1.00 27.78 ? 152 PRO A CB 1 ATOM 1233 C CG . PRO A 1 152 ? -20.192 78.104 11.610 1.00 27.64 ? 152 PRO A CG 1 ATOM 1234 C CD . PRO A 1 152 ? -20.038 78.847 12.914 1.00 28.25 ? 152 PRO A CD 1 ATOM 1235 N N . VAL A 1 153 ? -16.534 80.145 12.136 1.00 38.38 ? 153 VAL A N 1 ATOM 1236 C CA . VAL A 1 153 ? -15.353 80.972 11.892 1.00 38.38 ? 153 VAL A CA 1 ATOM 1237 C C . VAL A 1 153 ? -14.119 80.556 12.661 1.00 38.38 ? 153 VAL A C 1 ATOM 1238 O O . VAL A 1 153 ? -13.011 80.604 12.140 1.00 38.38 ? 153 VAL A O 1 ATOM 1239 C CB . VAL A 1 153 ? -15.599 82.432 12.285 1.00 39.07 ? 153 VAL A CB 1 ATOM 1240 C CG1 . VAL A 1 153 ? -14.510 83.315 11.711 1.00 52.74 ? 153 VAL A CG1 1 ATOM 1241 C CG2 . VAL A 1 153 ? -16.967 82.858 11.825 1.00 39.13 ? 153 VAL A CG2 1 ATOM 1242 N N . TYR A 1 154 ? -14.323 80.171 13.912 1.00 30.17 ? 154 TYR A N 1 ATOM 1243 C CA . TYR A 1 154 ? -13.237 79.799 14.802 1.00 30.17 ? 154 TYR A CA 1 ATOM 1244 C C . TYR A 1 154 ? -12.174 78.836 14.280 1.00 30.17 ? 154 TYR A C 1 ATOM 1245 O O . TYR A 1 154 ? -10.984 79.109 14.420 1.00 30.17 ? 154 TYR A O 1 ATOM 1246 C CB . TYR A 1 154 ? -13.817 79.270 16.114 1.00 10.54 ? 154 TYR A CB 1 ATOM 1247 C CG . TYR A 1 154 ? -14.702 80.259 16.825 1.00 10.54 ? 154 TYR A CG 1 ATOM 1248 C CD1 . TYR A 1 154 ? -14.769 81.596 16.424 1.00 13.16 ? 154 TYR A CD1 1 ATOM 1249 C CD2 . TYR A 1 154 ? -15.452 79.871 17.918 1.00 10.54 ? 154 TYR A CD2 1 ATOM 1250 C CE1 . TYR A 1 154 ? -15.566 82.518 17.102 1.00 10.54 ? 154 TYR A CE1 1 ATOM 1251 C CE2 . TYR A 1 154 ? -16.246 80.783 18.602 1.00 10.54 ? 154 TYR A CE2 1 ATOM 1252 C CZ . TYR A 1 154 ? -16.298 82.098 18.190 1.00 15.21 ? 154 TYR A CZ 1 ATOM 1253 O OH . TYR A 1 154 ? -17.086 82.973 18.891 1.00 17.94 ? 154 TYR A OH 1 ATOM 1254 N N . VAL A 1 155 ? -12.571 77.713 13.690 1.00 13.44 ? 155 VAL A N 1 ATOM 1255 C CA . VAL A 1 155 ? -11.555 76.797 13.212 1.00 13.44 ? 155 VAL A CA 1 ATOM 1256 C C . VAL A 1 155 ? -10.907 77.308 11.941 1.00 13.44 ? 155 VAL A C 1 ATOM 1257 O O . VAL A 1 155 ? -9.811 76.886 11.598 1.00 13.44 ? 155 VAL A O 1 ATOM 1258 C CB . VAL A 1 155 ? -12.107 75.389 12.998 1.00 10.36 ? 155 VAL A CB 1 ATOM 1259 C CG1 . VAL A 1 155 ? -12.821 74.950 14.236 1.00 10.36 ? 155 VAL A CG1 1 ATOM 1260 C CG2 . VAL A 1 155 ? -13.013 75.353 11.810 1.00 10.45 ? 155 VAL A CG2 1 ATOM 1261 N N . GLN A 1 156 ? -11.571 78.222 11.240 1.00 19.38 ? 156 GLN A N 1 ATOM 1262 C CA . GLN A 1 156 ? -10.986 78.785 10.031 1.00 19.38 ? 156 GLN A CA 1 ATOM 1263 C C . GLN A 1 156 ? -9.843 79.713 10.467 1.00 19.38 ? 156 GLN A C 1 ATOM 1264 O O . GLN A 1 156 ? -8.781 79.741 9.843 1.00 19.38 ? 156 GLN A O 1 ATOM 1265 C CB . GLN A 1 156 ? -12.035 79.555 9.222 1.00 26.16 ? 156 GLN A CB 1 ATOM 1266 C CG . GLN A 1 156 ? -13.276 78.732 8.846 1.00 26.16 ? 156 GLN A CG 1 ATOM 1267 C CD . GLN A 1 156 ? -14.201 79.428 7.839 1.00 40.65 ? 156 GLN A CD 1 ATOM 1268 O OE1 . GLN A 1 156 ? -14.343 80.650 7.840 1.00 33.16 ? 156 GLN A OE1 1 ATOM 1269 N NE2 . GLN A 1 156 ? -14.846 78.644 6.993 1.00 26.33 ? 156 GLN A NE2 1 ATOM 1270 N N . ARG A 1 157 ? -10.055 80.448 11.557 1.00 16.26 ? 157 ARG A N 1 ATOM 1271 C CA . ARG A 1 157 ? -9.048 81.361 12.092 1.00 16.26 ? 157 ARG A CA 1 ATOM 1272 C C . ARG A 1 157 ? -7.784 80.650 12.570 1.00 16.26 ? 157 ARG A C 1 ATOM 1273 O O . ARG A 1 157 ? -6.659 81.109 12.317 1.00 16.26 ? 157 ARG A O 1 ATOM 1274 C CB . ARG A 1 157 ? -9.604 82.135 13.271 1.00 19.11 ? 157 ARG A CB 1 ATOM 1275 C CG . ARG A 1 157 ? -10.495 83.282 12.938 1.00 19.11 ? 157 ARG A CG 1 ATOM 1276 C CD . ARG A 1 157 ? -11.046 83.800 14.239 1.00 21.14 ? 157 ARG A CD 1 ATOM 1277 N NE . ARG A 1 157 ? -11.927 84.950 14.108 1.00 19.11 ? 157 ARG A NE 1 ATOM 1278 C CZ . ARG A 1 157 ? -12.633 85.435 15.121 1.00 28.29 ? 157 ARG A CZ 1 ATOM 1279 N NH1 . ARG A 1 157 ? -12.547 84.849 16.311 1.00 19.11 ? 157 ARG A NH1 1 ATOM 1280 N NH2 . ARG A 1 157 ? -13.406 86.503 14.954 1.00 29.51 ? 157 ARG A NH2 1 ATOM 1281 N N . ALA A 1 158 ? -7.979 79.552 13.298 1.00 13.06 ? 158 ALA A N 1 ATOM 1282 C CA . ALA A 1 158 ? -6.875 78.770 13.825 1.00 13.06 ? 158 ALA A CA 1 ATOM 1283 C C . ALA A 1 158 ? -6.044 78.240 12.683 1.00 13.06 ? 158 ALA A C 1 ATOM 1284 O O . ALA A 1 158 ? -4.826 78.271 12.739 1.00 13.06 ? 158 ALA A O 1 ATOM 1285 C CB . ALA A 1 158 ? -7.394 77.622 14.651 1.00 4.65 ? 158 ALA A CB 1 ATOM 1286 N N . LYS A 1 159 ? -6.692 77.739 11.643 1.00 8.57 ? 159 LYS A N 1 ATOM 1287 C CA . LYS A 1 159 ? -5.944 77.217 10.514 1.00 8.57 ? 159 LYS A CA 1 ATOM 1288 C C . LYS A 1 159 ? -5.157 78.383 9.960 1.00 8.57 ? 159 LYS A C 1 ATOM 1289 O O . LYS A 1 159 ? -3.992 78.258 9.587 1.00 8.57 ? 159 LYS A O 1 ATOM 1290 C CB . LYS A 1 159 ? -6.900 76.668 9.456 1.00 10.67 ? 159 LYS A CB 1 ATOM 1291 C CG . LYS A 1 159 ? -6.227 76.057 8.243 1.00 10.67 ? 159 LYS A CG 1 ATOM 1292 C CD . LYS A 1 159 ? -7.270 75.685 7.230 1.00 10.67 ? 159 LYS A CD 1 ATOM 1293 C CE . LYS A 1 159 ? -6.668 75.223 5.924 1.00 10.67 ? 159 LYS A CE 1 ATOM 1294 N NZ . LYS A 1 159 ? -5.968 73.900 6.041 1.00 15.06 ? 159 LYS A NZ 1 ATOM 1295 N N . ALA A 1 160 ? -5.818 79.534 9.936 1.00 13.22 ? 160 ALA A N 1 ATOM 1296 C CA . ALA A 1 160 ? -5.244 80.769 9.432 1.00 13.22 ? 160 ALA A CA 1 ATOM 1297 C C . ALA A 1 160 ? -4.044 81.239 10.238 1.00 13.22 ? 160 ALA A C 1 ATOM 1298 O O . ALA A 1 160 ? -3.166 81.903 9.706 1.00 13.22 ? 160 ALA A O 1 ATOM 1299 C CB . ALA A 1 160 ? -6.302 81.833 9.418 1.00 4.65 ? 160 ALA A CB 1 ATOM 1300 N N . TYR A 1 161 ? -4.007 80.919 11.526 1.00 11.51 ? 161 TYR A N 1 ATOM 1301 C CA . TYR A 1 161 ? -2.877 81.336 12.348 1.00 11.51 ? 161 TYR A CA 1 ATOM 1302 C C . TYR A 1 161 ? -1.657 80.479 12.085 1.00 11.51 ? 161 TYR A C 1 ATOM 1303 O O . TYR A 1 161 ? -0.545 80.975 11.998 1.00 11.51 ? 161 TYR A O 1 ATOM 1304 C CB . TYR A 1 161 ? -3.200 81.267 13.838 1.00 68.36 ? 161 TYR A CB 1 ATOM 1305 C CG . TYR A 1 161 ? -2.026 81.716 14.682 1.00 68.36 ? 161 TYR A CG 1 ATOM 1306 C CD1 . TYR A 1 161 ? -1.607 83.046 14.664 1.00 72.64 ? 161 TYR A CD1 1 ATOM 1307 C CD2 . TYR A 1 161 ? -1.289 80.804 15.443 1.00 68.36 ? 161 TYR A CD2 1 ATOM 1308 C CE1 . TYR A 1 161 ? -0.480 83.464 15.374 1.00 72.79 ? 161 TYR A CE1 1 ATOM 1309 C CE2 . TYR A 1 161 ? -0.152 81.209 16.160 1.00 68.36 ? 161 TYR A CE2 1 ATOM 1310 C CZ . TYR A 1 161 ? 0.246 82.544 16.116 1.00 73.92 ? 161 TYR A CZ 1 ATOM 1311 O OH . TYR A 1 161 ? 1.377 82.966 16.784 1.00 71.85 ? 161 TYR A OH 1 ATOM 1312 N N . LEU A 1 162 ? -1.864 79.183 11.951 1.00 14.66 ? 162 LEU A N 1 ATOM 1313 C CA . LEU A 1 162 ? -0.751 78.286 11.719 1.00 14.66 ? 162 LEU A CA 1 ATOM 1314 C C . LEU A 1 162 ? -0.225 78.298 10.283 1.00 14.66 ? 162 LEU A C 1 ATOM 1315 O O . LEU A 1 162 ? 0.985 78.221 10.051 1.00 14.66 ? 162 LEU A O 1 ATOM 1316 C CB . LEU A 1 162 ? -1.153 76.858 12.100 1.00 15.45 ? 162 LEU A CB 1 ATOM 1317 C CG . LEU A 1 162 ? -1.485 76.537 13.553 1.00 15.45 ? 162 LEU A CG 1 ATOM 1318 C CD1 . LEU A 1 162 ? -1.945 75.105 13.640 1.00 15.45 ? 162 LEU A CD1 1 ATOM 1319 C CD2 . LEU A 1 162 ? -0.271 76.747 14.427 1.00 15.45 ? 162 LEU A CD2 1 ATOM 1320 N N . GLU A 1 163 ? -1.129 78.395 9.318 1.00 21.26 ? 163 GLU A N 1 ATOM 1321 C CA . GLU A 1 163 ? -0.719 78.370 7.928 1.00 21.51 ? 163 GLU A CA 1 ATOM 1322 C C . GLU A 1 163 ? -0.424 79.707 7.289 1.00 21.26 ? 163 GLU A C 1 ATOM 1323 O O . GLU A 1 163 ? 0.255 79.758 6.267 1.00 21.26 ? 163 GLU A O 1 ATOM 1324 C CB . GLU A 1 163 ? -1.767 77.642 7.093 1.00 13.42 ? 163 GLU A CB 1 ATOM 1325 C CG . GLU A 1 163 ? -1.963 76.198 7.501 1.00 16.13 ? 163 GLU A CG 1 ATOM 1326 C CD . GLU A 1 163 ? -2.912 75.473 6.586 1.00 14.99 ? 163 GLU A CD 1 ATOM 1327 O OE1 . GLU A 1 163 ? -3.668 76.177 5.880 1.00 20.38 ? 163 GLU A OE1 1 ATOM 1328 O OE2 . GLU A 1 163 ? -2.905 74.222 6.586 1.00 20.51 ? 163 GLU A OE2 1 ATOM 1329 N N . GLU A 1 164 ? -0.914 80.787 7.881 1.00 14.07 ? 164 GLU A N 1 ATOM 1330 C CA . GLU A 1 164 ? -0.695 82.090 7.290 1.00 15.32 ? 164 GLU A CA 1 ATOM 1331 C C . GLU A 1 164 ? -0.058 83.141 8.191 1.00 14.07 ? 164 GLU A C 1 ATOM 1332 O O . GLU A 1 164 ? 1.000 83.685 7.876 1.00 14.07 ? 164 GLU A O 1 ATOM 1333 C CB . GLU A 1 164 ? -2.016 82.621 6.739 1.00 20.45 ? 164 GLU A CB 1 ATOM 1334 C CG . GLU A 1 164 ? -2.730 81.648 5.824 1.00 38.34 ? 164 GLU A CG 1 ATOM 1335 C CD . GLU A 1 164 ? -3.970 82.241 5.173 1.00 50.24 ? 164 GLU A CD 1 ATOM 1336 O OE1 . GLU A 1 164 ? -4.701 83.000 5.850 1.00 55.72 ? 164 GLU A OE1 1 ATOM 1337 O OE2 . GLU A 1 164 ? -4.218 81.933 3.983 1.00 61.61 ? 164 GLU A OE2 1 ATOM 1338 N N . GLU A 1 165 ? -0.693 83.427 9.316 1.00 14.23 ? 165 GLU A N 1 ATOM 1339 C CA . GLU A 1 165 ? -0.187 84.453 10.204 1.00 14.23 ? 165 GLU A CA 1 ATOM 1340 C C . GLU A 1 165 ? 1.131 84.170 10.888 1.00 15.21 ? 165 GLU A C 1 ATOM 1341 O O . GLU A 1 165 ? 2.032 85.001 10.844 1.00 14.23 ? 165 GLU A O 1 ATOM 1342 C CB . GLU A 1 165 ? -1.249 84.799 11.236 1.00 48.56 ? 165 GLU A CB 1 ATOM 1343 C CG . GLU A 1 165 ? -2.485 85.419 10.613 1.00 66.67 ? 165 GLU A CG 1 ATOM 1344 C CD . GLU A 1 165 ? -3.556 85.711 11.630 1.00 72.53 ? 165 GLU A CD 1 ATOM 1345 O OE1 . GLU A 1 165 ? -3.263 86.430 12.607 1.00 79.17 ? 165 GLU A OE1 1 ATOM 1346 O OE2 . GLU A 1 165 ? -4.691 85.222 11.452 1.00 75.57 ? 165 GLU A OE2 1 ATOM 1347 N N . CYS A 1 166 ? 1.260 83.009 11.519 1.00 20.37 ? 166 CYS A N 1 ATOM 1348 C CA . CYS A 1 166 ? 2.498 82.679 12.205 1.00 20.37 ? 166 CYS A CA 1 ATOM 1349 C C . CYS A 1 166 ? 3.693 82.737 11.258 1.00 20.37 ? 166 CYS A C 1 ATOM 1350 O O . CYS A 1 166 ? 4.668 83.434 11.535 1.00 20.37 ? 166 CYS A O 1 ATOM 1351 C CB . CYS A 1 166 ? 2.410 81.297 12.850 1.00 17.39 ? 166 CYS A CB 1 ATOM 1352 S SG . CYS A 1 166 ? 3.586 81.047 14.227 1.00 19.50 ? 166 CYS A SG 1 ATOM 1353 N N . PRO A 1 167 ? 3.644 82.011 10.125 1.00 17.09 ? 167 PRO A N 1 ATOM 1354 C CA . PRO A 1 167 ? 4.774 82.047 9.195 1.00 17.09 ? 167 PRO A CA 1 ATOM 1355 C C . PRO A 1 167 ? 5.029 83.439 8.660 1.00 18.47 ? 167 PRO A C 1 ATOM 1356 O O . PRO A 1 167 ? 6.136 83.764 8.250 1.00 17.17 ? 167 PRO A O 1 ATOM 1357 C CB . PRO A 1 167 ? 4.363 81.056 8.112 1.00 6.27 ? 167 PRO A CB 1 ATOM 1358 C CG . PRO A 1 167 ? 2.908 81.099 8.155 1.00 10.50 ? 167 PRO A CG 1 ATOM 1359 C CD . PRO A 1 167 ? 2.603 81.109 9.615 1.00 5.67 ? 167 PRO A CD 1 ATOM 1360 N N . ALA A 1 168 ? 4.001 84.269 8.663 1.00 29.25 ? 168 ALA A N 1 ATOM 1361 C CA . ALA A 1 168 ? 4.182 85.625 8.198 1.00 30.37 ? 168 ALA A CA 1 ATOM 1362 C C . ALA A 1 168 ? 5.091 86.307 9.221 1.00 32.85 ? 168 ALA A C 1 ATOM 1363 O O . ALA A 1 168 ? 6.058 86.982 8.860 1.00 29.59 ? 168 ALA A O 1 ATOM 1364 C CB . ALA A 1 168 ? 2.855 86.318 8.118 1.00 4.65 ? 168 ALA A CB 1 ATOM 1365 N N . THR A 1 169 ? 4.779 86.117 10.502 1.00 25.92 ? 169 THR A N 1 ATOM 1366 C CA . THR A 1 169 ? 5.584 86.690 11.572 1.00 25.44 ? 169 THR A CA 1 ATOM 1367 C C . THR A 1 169 ? 7.008 86.141 11.511 1.00 25.44 ? 169 THR A C 1 ATOM 1368 O O . THR A 1 169 ? 7.956 86.899 11.631 1.00 25.44 ? 169 THR A O 1 ATOM 1369 C CB . THR A 1 169 ? 5.001 86.372 12.962 1.00 16.15 ? 169 THR A CB 1 ATOM 1370 O OG1 . THR A 1 169 ? 3.662 86.866 13.045 1.00 16.15 ? 169 THR A OG1 1 ATOM 1371 C CG2 . THR A 1 169 ? 5.832 87.028 14.047 1.00 16.15 ? 169 THR A CG2 1 ATOM 1372 N N . LEU A 1 170 ? 7.169 84.831 11.327 1.00 25.91 ? 170 LEU A N 1 ATOM 1373 C CA . LEU A 1 170 ? 8.514 84.277 11.248 1.00 25.91 ? 170 LEU A CA 1 ATOM 1374 C C . LEU A 1 170 ? 9.304 84.980 10.157 1.00 30.02 ? 170 LEU A C 1 ATOM 1375 O O . LEU A 1 170 ? 10.442 85.368 10.378 1.00 25.91 ? 170 LEU A O 1 ATOM 1376 C CB . LEU A 1 170 ? 8.502 82.764 10.970 1.00 4.65 ? 170 LEU A CB 1 ATOM 1377 C CG . LEU A 1 170 ? 9.881 82.143 10.641 1.00 4.65 ? 170 LEU A CG 1 ATOM 1378 C CD1 . LEU A 1 170 ? 10.898 82.534 11.663 1.00 4.65 ? 170 LEU A CD1 1 ATOM 1379 C CD2 . LEU A 1 170 ? 9.792 80.646 10.597 1.00 4.65 ? 170 LEU A CD2 1 ATOM 1380 N N . ARG A 1 171 ? 8.707 85.153 8.981 1.00 14.99 ? 171 ARG A N 1 ATOM 1381 C CA . ARG A 1 171 ? 9.403 85.815 7.882 1.00 15.38 ? 171 ARG A CA 1 ATOM 1382 C C . ARG A 1 171 ? 9.750 87.257 8.222 1.00 13.74 ? 171 ARG A C 1 ATOM 1383 O O . ARG A 1 171 ? 10.859 87.710 7.983 1.00 21.48 ? 171 ARG A O 1 ATOM 1384 C CB . ARG A 1 171 ? 8.562 85.770 6.607 1.00 4.65 ? 171 ARG A CB 1 ATOM 1385 C CG . ARG A 1 171 ? 8.478 84.399 5.958 1.00 4.65 ? 171 ARG A CG 1 ATOM 1386 C CD . ARG A 1 171 ? 7.608 84.488 4.723 1.00 9.83 ? 171 ARG A CD 1 ATOM 1387 N NE . ARG A 1 171 ? 6.996 83.217 4.333 1.00 24.08 ? 171 ARG A NE 1 ATOM 1388 C CZ . ARG A 1 171 ? 7.647 82.210 3.763 1.00 14.36 ? 171 ARG A CZ 1 ATOM 1389 N NH1 . ARG A 1 171 ? 8.949 82.300 3.507 1.00 30.96 ? 171 ARG A NH1 1 ATOM 1390 N NH2 . ARG A 1 171 ? 6.985 81.118 3.433 1.00 17.92 ? 171 ARG A NH2 1 ATOM 1391 N N . LYS A 1 172 ? 8.793 87.981 8.779 1.00 10.03 ? 172 LYS A N 1 ATOM 1392 C CA . LYS A 1 172 ? 9.032 89.357 9.165 1.00 10.03 ? 172 LYS A CA 1 ATOM 1393 C C . LYS A 1 172 ? 10.200 89.379 10.135 1.00 20.90 ? 172 LYS A C 1 ATOM 1394 O O . LYS A 1 172 ? 11.191 90.051 9.909 1.00 13.50 ? 172 LYS A O 1 ATOM 1395 C CB . LYS A 1 172 ? 7.790 89.933 9.833 1.00 9.32 ? 172 LYS A CB 1 ATOM 1396 C CG . LYS A 1 172 ? 7.974 91.320 10.387 1.00 16.91 ? 172 LYS A CG 1 ATOM 1397 C CD . LYS A 1 172 ? 6.704 91.778 11.070 1.00 28.49 ? 172 LYS A CD 1 ATOM 1398 C CE . LYS A 1 172 ? 6.888 93.110 11.768 1.00 36.77 ? 172 LYS A CE 1 ATOM 1399 N NZ . LYS A 1 172 ? 5.644 93.505 12.489 1.00 40.39 ? 172 LYS A NZ 1 ATOM 1400 N N . TYR A 1 173 ? 10.076 88.624 11.215 1.00 16.65 ? 173 TYR A N 1 ATOM 1401 C CA . TYR A 1 173 ? 11.119 88.548 12.222 1.00 15.94 ? 173 TYR A CA 1 ATOM 1402 C C . TYR A 1 173 ? 12.457 88.172 11.625 1.00 18.14 ? 173 TYR A C 1 ATOM 1403 O O . TYR A 1 173 ? 13.492 88.587 12.125 1.00 21.32 ? 173 TYR A O 1 ATOM 1404 C CB . TYR A 1 173 ? 10.747 87.525 13.299 1.00 9.65 ? 173 TYR A CB 1 ATOM 1405 C CG . TYR A 1 173 ? 9.717 88.012 14.297 1.00 11.08 ? 173 TYR A CG 1 ATOM 1406 C CD1 . TYR A 1 173 ? 9.052 89.221 14.107 1.00 9.65 ? 173 TYR A CD1 1 ATOM 1407 C CD2 . TYR A 1 173 ? 9.395 87.253 15.418 1.00 9.65 ? 173 TYR A CD2 1 ATOM 1408 C CE1 . TYR A 1 173 ? 8.096 89.664 15.004 1.00 9.65 ? 173 TYR A CE1 1 ATOM 1409 C CE2 . TYR A 1 173 ? 8.440 87.683 16.320 1.00 9.65 ? 173 TYR A CE2 1 ATOM 1410 C CZ . TYR A 1 173 ? 7.792 88.896 16.112 1.00 9.65 ? 173 TYR A CZ 1 ATOM 1411 O OH . TYR A 1 173 ? 6.870 89.363 17.024 1.00 9.65 ? 173 TYR A OH 1 ATOM 1412 N N . LEU A 1 174 ? 12.441 87.385 10.558 1.00 17.65 ? 174 LEU A N 1 ATOM 1413 C CA . LEU A 1 174 ? 13.679 86.957 9.921 1.00 24.41 ? 174 LEU A CA 1 ATOM 1414 C C . LEU A 1 174 ? 14.396 88.059 9.156 1.00 28.60 ? 174 LEU A C 1 ATOM 1415 O O . LEU A 1 174 ? 15.622 88.010 9.001 1.00 27.00 ? 174 LEU A O 1 ATOM 1416 C CB . LEU A 1 174 ? 13.418 85.781 8.987 1.00 8.08 ? 174 LEU A CB 1 ATOM 1417 C CG . LEU A 1 174 ? 13.190 84.448 9.677 1.00 17.57 ? 174 LEU A CG 1 ATOM 1418 C CD1 . LEU A 1 174 ? 12.980 83.369 8.644 1.00 17.41 ? 174 LEU A CD1 1 ATOM 1419 C CD2 . LEU A 1 174 ? 14.387 84.123 10.536 1.00 10.23 ? 174 LEU A CD2 1 ATOM 1420 N N . LYS A 1 175 ? 13.636 89.040 8.674 1.00 27.55 ? 175 LYS A N 1 ATOM 1421 C CA . LYS A 1 175 ? 14.210 90.152 7.936 1.00 38.08 ? 175 LYS A CA 1 ATOM 1422 C C . LYS A 1 175 ? 15.085 90.992 8.861 1.00 36.24 ? 175 LYS A C 1 ATOM 1423 O O . LYS A 1 175 ? 16.067 91.587 8.423 1.00 37.76 ? 175 LYS A O 1 ATOM 1424 C CB . LYS A 1 175 ? 13.106 91.020 7.344 1.00 69.24 ? 175 LYS A CB 1 ATOM 1425 C CG . LYS A 1 175 ? 12.259 90.308 6.324 1.00 79.00 ? 175 LYS A CG 1 ATOM 1426 C CD . LYS A 1 175 ? 11.103 91.183 5.882 1.00 88.95 ? 175 LYS A CD 1 ATOM 1427 C CE . LYS A 1 175 ? 10.167 90.433 4.948 1.00 94.70 ? 175 LYS A CE 1 ATOM 1428 N NZ . LYS A 1 175 ? 8.982 91.254 4.593 1.00 98.10 ? 175 LYS A NZ 1 ATOM 1429 N N . TYR A 1 176 ? 14.732 91.027 10.141 1.00 32.55 ? 176 TYR A N 1 ATOM 1430 C CA . TYR A 1 176 ? 15.483 91.791 11.131 1.00 30.51 ? 176 TYR A CA 1 ATOM 1431 C C . TYR A 1 176 ? 16.474 90.921 11.918 1.00 29.58 ? 176 TYR A C 1 ATOM 1432 O O . TYR A 1 176 ? 17.328 91.446 12.642 1.00 30.17 ? 176 TYR A O 1 ATOM 1433 C CB . TYR A 1 176 ? 14.521 92.441 12.128 1.00 24.55 ? 176 TYR A CB 1 ATOM 1434 C CG . TYR A 1 176 ? 13.551 93.428 11.525 1.00 41.72 ? 176 TYR A CG 1 ATOM 1435 C CD1 . TYR A 1 176 ? 12.754 93.081 10.436 1.00 41.51 ? 176 TYR A CD1 1 ATOM 1436 C CD2 . TYR A 1 176 ? 13.446 94.720 12.032 1.00 40.42 ? 176 TYR A CD2 1 ATOM 1437 C CE1 . TYR A 1 176 ? 11.878 94.000 9.860 1.00 45.02 ? 176 TYR A CE1 1 ATOM 1438 C CE2 . TYR A 1 176 ? 12.579 95.645 11.464 1.00 41.71 ? 176 TYR A CE2 1 ATOM 1439 C CZ . TYR A 1 176 ? 11.797 95.282 10.378 1.00 43.92 ? 176 TYR A CZ 1 ATOM 1440 O OH . TYR A 1 176 ? 10.945 96.202 9.804 1.00 43.74 ? 176 TYR A OH 1 ATOM 1441 N N . SER A 1 177 ? 16.373 89.601 11.763 1.00 20.99 ? 177 SER A N 1 ATOM 1442 C CA . SER A 1 177 ? 17.210 88.673 12.513 1.00 20.45 ? 177 SER A CA 1 ATOM 1443 C C . SER A 1 177 ? 18.349 88.027 11.753 1.00 30.56 ? 177 SER A C 1 ATOM 1444 O O . SER A 1 177 ? 18.959 87.066 12.237 1.00 29.63 ? 177 SER A O 1 ATOM 1445 C CB . SER A 1 177 ? 16.333 87.579 13.118 1.00 38.05 ? 177 SER A CB 1 ATOM 1446 O OG . SER A 1 177 ? 15.291 88.141 13.900 1.00 28.41 ? 177 SER A OG 1 ATOM 1447 N N . LYS A 1 178 ? 18.634 88.546 10.566 1.00 43.46 ? 178 LYS A N 1 ATOM 1448 C CA . LYS A 1 178 ? 19.728 88.024 9.758 1.00 47.00 ? 178 LYS A CA 1 ATOM 1449 C C . LYS A 1 178 ? 21.021 88.088 10.570 1.00 41.76 ? 178 LYS A C 1 ATOM 1450 O O . LYS A 1 178 ? 21.608 87.061 10.890 1.00 51.17 ? 178 LYS A O 1 ATOM 1451 C CB . LYS A 1 178 ? 19.870 88.851 8.479 1.00 92.48 ? 178 LYS A CB 1 ATOM 1452 C CG . LYS A 1 178 ? 18.761 88.626 7.460 1.00 97.79 ? 178 LYS A CG 1 ATOM 1453 C CD . LYS A 1 178 ? 18.811 89.673 6.355 1.00 102.30 ? 178 LYS A CD 1 ATOM 1454 C CE . LYS A 1 178 ? 17.967 89.277 5.153 1.00 107.58 ? 178 LYS A CE 1 ATOM 1455 N NZ . LYS A 1 178 ? 18.579 88.144 4.398 1.00 108.68 ? 178 LYS A NZ 1 ATOM 1456 N N . ASN A 1 179 ? 21.446 89.301 10.913 1.00 65.09 ? 179 ASN A N 1 ATOM 1457 C CA . ASN A 1 179 ? 22.664 89.507 11.694 1.00 71.08 ? 179 ASN A CA 1 ATOM 1458 C C . ASN A 1 179 ? 22.676 88.756 13.018 1.00 73.13 ? 179 ASN A C 1 ATOM 1459 O O . ASN A 1 179 ? 23.569 88.977 13.840 1.00 71.61 ? 179 ASN A O 1 ATOM 1460 C CB . ASN A 1 179 ? 22.880 90.996 11.994 1.00 89.72 ? 179 ASN A CB 1 ATOM 1461 C CG . ASN A 1 179 ? 23.391 91.770 10.797 1.00 104.05 ? 179 ASN A CG 1 ATOM 1462 O OD1 . ASN A 1 179 ? 24.404 91.412 10.197 1.00 110.58 ? 179 ASN A OD1 1 ATOM 1463 N ND2 . ASN A 1 179 ? 22.698 92.847 10.450 1.00 102.78 ? 179 ASN A ND2 1 ATOM 1464 N N . ILE A 1 180 ? 21.688 87.891 13.240 1.00 34.71 ? 180 ILE A N 1 ATOM 1465 C CA . ILE A 1 180 ? 21.627 87.123 14.478 1.00 27.31 ? 180 ILE A CA 1 ATOM 1466 C C . ILE A 1 180 ? 21.585 85.620 14.255 1.00 25.92 ? 180 ILE A C 1 ATOM 1467 O O . ILE A 1 180 ? 22.510 84.910 14.637 1.00 26.50 ? 180 ILE A O 1 ATOM 1468 C CB . ILE A 1 180 ? 20.421 87.509 15.336 1.00 4.77 ? 180 ILE A CB 1 ATOM 1469 C CG1 . ILE A 1 180 ? 20.584 88.939 15.855 1.00 4.65 ? 180 ILE A CG1 1 ATOM 1470 C CG2 . ILE A 1 180 ? 20.327 86.570 16.512 1.00 4.65 ? 180 ILE A CG2 1 ATOM 1471 C CD1 . ILE A 1 180 ? 19.487 89.420 16.835 1.00 4.65 ? 180 ILE A CD1 1 ATOM 1472 N N . LEU A 1 181 ? 20.518 85.128 13.637 1.00 21.06 ? 181 LEU A N 1 ATOM 1473 C CA . LEU A 1 181 ? 20.413 83.693 13.413 1.00 21.06 ? 181 LEU A CA 1 ATOM 1474 C C . LEU A 1 181 ? 21.402 83.150 12.394 1.00 23.65 ? 181 LEU A C 1 ATOM 1475 O O . LEU A 1 181 ? 21.831 82.007 12.512 1.00 21.06 ? 181 LEU A O 1 ATOM 1476 C CB . LEU A 1 181 ? 18.986 83.317 13.018 1.00 7.34 ? 181 LEU A CB 1 ATOM 1477 C CG . LEU A 1 181 ? 17.913 83.648 14.065 1.00 7.34 ? 181 LEU A CG 1 ATOM 1478 C CD1 . LEU A 1 181 ? 16.541 83.378 13.494 1.00 9.61 ? 181 LEU A CD1 1 ATOM 1479 C CD2 . LEU A 1 181 ? 18.125 82.836 15.317 1.00 7.34 ? 181 LEU A CD2 1 ATOM 1480 N N . ASP A 1 182 ? 21.789 83.961 11.413 1.00 30.86 ? 182 ASP A N 1 ATOM 1481 C CA . ASP A 1 182 ? 22.736 83.505 10.394 1.00 34.00 ? 182 ASP A CA 1 ATOM 1482 C C . ASP A 1 182 ? 24.197 83.660 10.756 1.00 37.68 ? 182 ASP A C 1 ATOM 1483 O O . ASP A 1 182 ? 25.067 83.270 9.984 1.00 36.39 ? 182 ASP A O 1 ATOM 1484 C CB . ASP A 1 182 ? 22.492 84.210 9.071 1.00 38.88 ? 182 ASP A CB 1 ATOM 1485 C CG . ASP A 1 182 ? 21.151 83.894 8.504 1.00 51.81 ? 182 ASP A CG 1 ATOM 1486 O OD1 . ASP A 1 182 ? 20.744 82.725 8.646 1.00 52.42 ? 182 ASP A OD1 1 ATOM 1487 O OD2 . ASP A 1 182 ? 20.513 84.796 7.918 1.00 56.08 ? 182 ASP A OD2 1 ATOM 1488 N N . ARG A 1 183 ? 24.470 84.241 11.917 1.00 12.24 ? 183 ARG A N 1 ATOM 1489 C CA . ARG A 1 183 ? 25.841 84.410 12.367 1.00 12.93 ? 183 ARG A CA 1 ATOM 1490 C C . ARG A 1 183 ? 26.682 83.148 12.229 1.00 12.21 ? 183 ARG A C 1 ATOM 1491 O O . ARG A 1 183 ? 26.171 82.029 12.182 1.00 9.51 ? 183 ARG A O 1 ATOM 1492 C CB . ARG A 1 183 ? 25.866 84.855 13.824 1.00 23.01 ? 183 ARG A CB 1 ATOM 1493 C CG . ARG A 1 183 ? 25.859 86.343 13.991 1.00 25.74 ? 183 ARG A CG 1 ATOM 1494 C CD . ARG A 1 183 ? 25.205 86.735 15.283 1.00 42.48 ? 183 ARG A CD 1 ATOM 1495 N NE . ARG A 1 183 ? 25.822 86.081 16.424 1.00 42.31 ? 183 ARG A NE 1 ATOM 1496 C CZ . ARG A 1 183 ? 25.160 85.327 17.290 1.00 34.80 ? 183 ARG A CZ 1 ATOM 1497 N NH1 . ARG A 1 183 ? 23.860 85.127 17.141 1.00 22.65 ? 183 ARG A NH1 1 ATOM 1498 N NH2 . ARG A 1 183 ? 25.795 84.793 18.318 1.00 21.74 ? 183 ARG A NH2 1 ATOM 1499 N N . GLN A 1 184 ? 27.985 83.367 12.149 1.00 31.75 ? 184 GLN A N 1 ATOM 1500 C CA . GLN A 1 184 ? 28.983 82.322 12.051 1.00 31.50 ? 184 GLN A CA 1 ATOM 1501 C C . GLN A 1 184 ? 30.195 82.911 12.754 1.00 34.73 ? 184 GLN A C 1 ATOM 1502 O O . GLN A 1 184 ? 31.206 83.208 12.133 1.00 35.06 ? 184 GLN A O 1 ATOM 1503 C CB . GLN A 1 184 ? 29.293 82.011 10.589 1.00 28.80 ? 184 GLN A CB 1 ATOM 1504 C CG . GLN A 1 184 ? 28.360 80.979 9.975 1.00 33.53 ? 184 GLN A CG 1 ATOM 1505 C CD . GLN A 1 184 ? 28.614 79.576 10.502 1.00 34.20 ? 184 GLN A CD 1 ATOM 1506 O OE1 . GLN A 1 184 ? 27.825 78.658 10.285 1.00 37.19 ? 184 GLN A OE1 1 ATOM 1507 N NE2 . GLN A 1 184 ? 29.726 79.404 11.190 1.00 25.49 ? 184 GLN A NE2 1 ATOM 1508 N N . ASP A 1 185 ? 30.058 83.103 14.062 1.00 22.07 ? 185 ASP A N 1 ATOM 1509 C CA . ASP A 1 185 ? 31.104 83.684 14.880 1.00 21.07 ? 185 ASP A CA 1 ATOM 1510 C C . ASP A 1 185 ? 32.156 82.667 15.247 1.00 27.11 ? 185 ASP A C 1 ATOM 1511 O O . ASP A 1 185 ? 31.856 81.666 15.889 1.00 23.86 ? 185 ASP A O 1 ATOM 1512 C CB . ASP A 1 185 ? 30.510 84.266 16.152 1.00 30.13 ? 185 ASP A CB 1 ATOM 1513 C CG . ASP A 1 185 ? 29.506 85.356 15.874 1.00 39.10 ? 185 ASP A CG 1 ATOM 1514 O OD1 . ASP A 1 185 ? 29.467 85.840 14.720 1.00 42.83 ? 185 ASP A OD1 1 ATOM 1515 O OD2 . ASP A 1 185 ? 28.769 85.739 16.811 1.00 40.30 ? 185 ASP A OD2 1 ATOM 1516 N N . PRO A 1 186 ? 33.417 82.916 14.855 1.00 28.24 ? 186 PRO A N 1 ATOM 1517 C CA . PRO A 1 186 ? 34.504 81.990 15.162 1.00 28.51 ? 186 PRO A CA 1 ATOM 1518 C C . PRO A 1 186 ? 34.719 81.904 16.658 1.00 28.24 ? 186 PRO A C 1 ATOM 1519 O O . PRO A 1 186 ? 34.547 82.882 17.378 1.00 29.56 ? 186 PRO A O 1 ATOM 1520 C CB . PRO A 1 186 ? 35.679 82.595 14.415 1.00 26.05 ? 186 PRO A CB 1 ATOM 1521 C CG . PRO A 1 186 ? 35.387 84.049 14.485 1.00 26.85 ? 186 PRO A CG 1 ATOM 1522 C CD . PRO A 1 186 ? 33.934 84.094 14.142 1.00 25.00 ? 186 PRO A CD 1 ATOM 1523 N N . PRO A 1 187 ? 35.104 80.722 17.142 1.00 15.31 ? 187 PRO A N 1 ATOM 1524 C CA . PRO A 1 187 ? 35.344 80.460 18.558 1.00 13.93 ? 187 PRO A CA 1 ATOM 1525 C C . PRO A 1 187 ? 36.713 80.879 19.000 1.00 14.79 ? 187 PRO A C 1 ATOM 1526 O O . PRO A 1 187 ? 37.681 80.578 18.324 1.00 14.66 ? 187 PRO A O 1 ATOM 1527 C CB . PRO A 1 187 ? 35.194 78.957 18.638 1.00 11.70 ? 187 PRO A CB 1 ATOM 1528 C CG . PRO A 1 187 ? 35.901 78.539 17.386 1.00 13.78 ? 187 PRO A CG 1 ATOM 1529 C CD . PRO A 1 187 ? 35.387 79.518 16.340 1.00 9.71 ? 187 PRO A CD 1 ATOM 1530 N N . SER A 1 188 ? 36.800 81.571 20.129 1.00 13.00 ? 188 SER A N 1 ATOM 1531 C CA . SER A 1 188 ? 38.097 81.962 20.664 1.00 16.97 ? 188 SER A CA 1 ATOM 1532 C C . SER A 1 188 ? 38.446 80.882 21.691 1.00 23.42 ? 188 SER A C 1 ATOM 1533 O O . SER A 1 188 ? 37.554 80.329 22.324 1.00 16.01 ? 188 SER A O 1 ATOM 1534 C CB . SER A 1 188 ? 38.011 83.331 21.338 1.00 28.84 ? 188 SER A CB 1 ATOM 1535 O OG . SER A 1 188 ? 37.544 84.310 20.429 1.00 40.44 ? 188 SER A OG 1 ATOM 1536 N N . VAL A 1 189 ? 39.722 80.548 21.848 1.00 25.20 ? 189 VAL A N 1 ATOM 1537 C CA . VAL A 1 189 ? 40.069 79.526 22.827 1.00 31.43 ? 189 VAL A CA 1 ATOM 1538 C C . VAL A 1 189 ? 41.098 79.993 23.842 1.00 36.39 ? 189 VAL A C 1 ATOM 1539 O O . VAL A 1 189 ? 41.764 81.005 23.655 1.00 36.25 ? 189 VAL A O 1 ATOM 1540 C CB . VAL A 1 189 ? 40.580 78.227 22.155 1.00 20.33 ? 189 VAL A CB 1 ATOM 1541 C CG1 . VAL A 1 189 ? 40.041 78.133 20.745 1.00 15.40 ? 189 VAL A CG1 1 ATOM 1542 C CG2 . VAL A 1 189 ? 42.089 78.168 22.189 1.00 36.18 ? 189 VAL A CG2 1 ATOM 1543 N N . VAL A 1 190 ? 41.199 79.235 24.928 1.00 30.03 ? 190 VAL A N 1 ATOM 1544 C CA . VAL A 1 190 ? 42.128 79.501 26.018 1.00 27.95 ? 190 VAL A CA 1 ATOM 1545 C C . VAL A 1 190 ? 42.446 78.150 26.626 1.00 35.81 ? 190 VAL A C 1 ATOM 1546 O O . VAL A 1 190 ? 41.545 77.435 27.047 1.00 28.53 ? 190 VAL A O 1 ATOM 1547 C CB . VAL A 1 190 ? 41.490 80.348 27.144 1.00 21.72 ? 190 VAL A CB 1 ATOM 1548 C CG1 . VAL A 1 190 ? 42.555 80.866 28.076 1.00 17.11 ? 190 VAL A CG1 1 ATOM 1549 C CG2 . VAL A 1 190 ? 40.708 81.488 26.570 1.00 32.05 ? 190 VAL A CG2 1 ATOM 1550 N N . VAL A 1 191 ? 43.718 77.784 26.648 1.00 26.65 ? 191 VAL A N 1 ATOM 1551 C CA . VAL A 1 191 ? 44.116 76.526 27.254 1.00 23.92 ? 191 VAL A CA 1 ATOM 1552 C C . VAL A 1 191 ? 44.721 76.888 28.596 1.00 25.93 ? 191 VAL A C 1 ATOM 1553 O O . VAL A 1 191 ? 45.711 77.604 28.670 1.00 23.54 ? 191 VAL A O 1 ATOM 1554 C CB . VAL A 1 191 ? 45.162 75.777 26.424 1.00 20.12 ? 191 VAL A CB 1 ATOM 1555 C CG1 . VAL A 1 191 ? 45.696 74.619 27.223 1.00 22.23 ? 191 VAL A CG1 1 ATOM 1556 C CG2 . VAL A 1 191 ? 44.543 75.257 25.155 1.00 11.88 ? 191 VAL A CG2 1 ATOM 1557 N N . THR A 1 192 ? 44.100 76.411 29.660 1.00 27.89 ? 192 THR A N 1 ATOM 1558 C CA . THR A 1 192 ? 44.580 76.693 30.993 1.00 23.75 ? 192 THR A CA 1 ATOM 1559 C C . THR A 1 192 ? 44.774 75.370 31.721 1.00 26.09 ? 192 THR A C 1 ATOM 1560 O O . THR A 1 192 ? 44.141 74.373 31.384 1.00 27.54 ? 192 THR A O 1 ATOM 1561 C CB . THR A 1 192 ? 43.573 77.563 31.753 1.00 47.62 ? 192 THR A CB 1 ATOM 1562 O OG1 . THR A 1 192 ? 44.175 78.038 32.964 1.00 64.71 ? 192 THR A OG1 1 ATOM 1563 C CG2 . THR A 1 192 ? 42.311 76.754 32.081 1.00 42.80 ? 192 THR A CG2 1 ATOM 1564 N N . SER A 1 193 ? 45.660 75.354 32.710 1.00 53.83 ? 193 SER A N 1 ATOM 1565 C CA . SER A 1 193 ? 45.917 74.136 33.466 1.00 58.51 ? 193 SER A CA 1 ATOM 1566 C C . SER A 1 193 ? 45.827 74.461 34.933 1.00 57.46 ? 193 SER A C 1 ATOM 1567 O O . SER A 1 193 ? 46.353 75.480 35.379 1.00 52.89 ? 193 SER A O 1 ATOM 1568 C CB . SER A 1 193 ? 47.312 73.599 33.175 1.00 66.58 ? 193 SER A CB 1 ATOM 1569 O OG . SER A 1 193 ? 48.293 74.457 33.733 1.00 69.91 ? 193 SER A OG 1 ATOM 1570 N N . HIS A 1 194 ? 45.157 73.596 35.682 1.00 92.19 ? 194 HIS A N 1 ATOM 1571 C CA . HIS A 1 194 ? 45.023 73.807 37.108 1.00 97.85 ? 194 HIS A CA 1 ATOM 1572 C C . HIS A 1 194 ? 45.553 72.591 37.849 1.00 96.23 ? 194 HIS A C 1 ATOM 1573 O O . HIS A 1 194 ? 45.300 71.446 37.462 1.00 84.63 ? 194 HIS A O 1 ATOM 1574 C CB . HIS A 1 194 ? 43.563 74.058 37.482 1.00 140.81 ? 194 HIS A CB 1 ATOM 1575 C CG . HIS A 1 194 ? 43.398 74.879 38.723 1.00 152.12 ? 194 HIS A CG 1 ATOM 1576 N ND1 . HIS A 1 194 ? 43.952 74.519 39.933 1.00 155.88 ? 194 HIS A ND1 1 ATOM 1577 C CD2 . HIS A 1 194 ? 42.763 76.056 38.936 1.00 155.82 ? 194 HIS A CD2 1 ATOM 1578 C CE1 . HIS A 1 194 ? 43.666 75.439 40.837 1.00 161.01 ? 194 HIS A CE1 1 ATOM 1579 N NE2 . HIS A 1 194 ? 42.945 76.382 40.258 1.00 159.97 ? 194 HIS A NE2 1 ATOM 1580 N N . GLN A 1 195 ? 46.306 72.855 38.909 1.00 75.99 ? 195 GLN A N 1 ATOM 1581 C CA . GLN A 1 195 ? 46.888 71.803 39.728 1.00 86.00 ? 195 GLN A CA 1 ATOM 1582 C C . GLN A 1 195 ? 46.253 71.843 41.111 1.00 88.61 ? 195 GLN A C 1 ATOM 1583 O O . GLN A 1 195 ? 46.327 72.856 41.808 1.00 85.38 ? 195 GLN A O 1 ATOM 1584 C CB . GLN A 1 195 ? 48.403 72.005 39.849 1.00 107.55 ? 195 GLN A CB 1 ATOM 1585 C CG . GLN A 1 195 ? 49.122 70.986 40.734 1.00 108.06 ? 195 GLN A CG 1 ATOM 1586 C CD . GLN A 1 195 ? 49.173 69.600 40.119 1.00 110.41 ? 195 GLN A CD 1 ATOM 1587 O OE1 . GLN A 1 195 ? 48.140 68.998 39.827 1.00 113.81 ? 195 GLN A OE1 1 ATOM 1588 N NE2 . GLN A 1 195 ? 50.382 69.086 39.919 1.00 107.19 ? 195 GLN A NE2 1 ATOM 1589 N N . ALA A 1 196 ? 45.614 70.745 41.498 1.00 129.91 ? 196 ALA A N 1 ATOM 1590 C CA . ALA A 1 196 ? 44.982 70.662 42.806 1.00 134.40 ? 196 ALA A CA 1 ATOM 1591 C C . ALA A 1 196 ? 45.987 70.066 43.787 1.00 135.80 ? 196 ALA A C 1 ATOM 1592 O O . ALA A 1 196 ? 46.817 69.237 43.411 1.00 136.14 ? 196 ALA A O 1 ATOM 1593 C CB . ALA A 1 196 ? 43.734 69.797 42.733 1.00 104.50 ? 196 ALA A CB 1 ATOM 1594 N N . PRO A 1 197 ? 45.931 70.486 45.060 1.00 124.77 ? 197 PRO A N 1 ATOM 1595 C CA . PRO A 1 197 ? 46.848 69.984 46.087 1.00 124.77 ? 197 PRO A CA 1 ATOM 1596 C C . PRO A 1 197 ? 46.632 68.518 46.458 1.00 124.40 ? 197 PRO A C 1 ATOM 1597 O O . PRO A 1 197 ? 45.964 68.214 47.445 1.00 126.40 ? 197 PRO A O 1 ATOM 1598 C CB . PRO A 1 197 ? 46.589 70.925 47.261 1.00 129.52 ? 197 PRO A CB 1 ATOM 1599 C CG . PRO A 1 197 ? 45.132 71.243 47.108 1.00 131.43 ? 197 PRO A CG 1 ATOM 1600 C CD . PRO A 1 197 ? 45.014 71.495 45.623 1.00 133.20 ? 197 PRO A CD 1 ATOM 1601 N N . GLY A 1 198 ? 47.204 67.612 45.668 1.00 87.22 ? 198 GLY A N 1 ATOM 1602 C CA . GLY A 1 198 ? 47.052 66.197 45.950 1.00 84.19 ? 198 GLY A CA 1 ATOM 1603 C C . GLY A 1 198 ? 46.860 65.325 44.724 1.00 85.25 ? 198 GLY A C 1 ATOM 1604 O O . GLY A 1 198 ? 47.528 64.301 44.581 1.00 86.21 ? 198 GLY A O 1 ATOM 1605 N N . GLU A 1 199 ? 45.949 65.727 43.840 1.00 140.86 ? 199 GLU A N 1 ATOM 1606 C CA . GLU A 1 199 ? 45.659 64.976 42.615 1.00 137.99 ? 199 GLU A CA 1 ATOM 1607 C C . GLU A 1 199 ? 46.677 65.265 41.511 1.00 134.49 ? 199 GLU A C 1 ATOM 1608 O O . GLU A 1 199 ? 47.733 65.845 41.762 1.00 129.80 ? 199 GLU A O 1 ATOM 1609 C CB . GLU A 1 199 ? 44.250 65.317 42.105 1.00 133.20 ? 199 GLU A CB 1 ATOM 1610 C CG . GLU A 1 199 ? 43.120 65.004 43.084 1.00 135.61 ? 199 GLU A CG 1 ATOM 1611 C CD . GLU A 1 199 ? 41.756 65.450 42.575 1.00 137.08 ? 199 GLU A CD 1 ATOM 1612 O OE1 . GLU A 1 199 ? 41.332 64.971 41.502 1.00 138.28 ? 199 GLU A OE1 1 ATOM 1613 O OE2 . GLU A 1 199 ? 41.109 66.278 43.250 1.00 136.39 ? 199 GLU A OE2 1 ATOM 1614 N N . LYS A 1 200 ? 46.349 64.854 40.288 1.00 61.85 ? 200 LYS A N 1 ATOM 1615 C CA . LYS A 1 200 ? 47.221 65.070 39.135 1.00 59.06 ? 200 LYS A CA 1 ATOM 1616 C C . LYS A 1 200 ? 46.943 66.440 38.518 1.00 60.39 ? 200 LYS A C 1 ATOM 1617 O O . LYS A 1 200 ? 46.021 67.137 38.937 1.00 59.92 ? 200 LYS A O 1 ATOM 1618 C CB . LYS A 1 200 ? 46.975 63.987 38.080 1.00 86.92 ? 200 LYS A CB 1 ATOM 1619 C CG . LYS A 1 200 ? 47.166 62.572 38.582 1.00 85.84 ? 200 LYS A CG 1 ATOM 1620 C CD . LYS A 1 200 ? 46.911 61.558 37.481 1.00 82.23 ? 200 LYS A CD 1 ATOM 1621 C CE . LYS A 1 200 ? 47.192 60.137 37.964 1.00 92.90 ? 200 LYS A CE 1 ATOM 1622 N NZ . LYS A 1 200 ? 48.613 59.937 38.383 1.00 93.52 ? 200 LYS A NZ 1 ATOM 1623 N N . LYS A 1 201 ? 47.739 66.834 37.530 1.00 85.76 ? 201 LYS A N 1 ATOM 1624 C CA . LYS A 1 201 ? 47.513 68.117 36.879 1.00 82.09 ? 201 LYS A CA 1 ATOM 1625 C C . LYS A 1 201 ? 46.406 67.941 35.836 1.00 78.61 ? 201 LYS A C 1 ATOM 1626 O O . LYS A 1 201 ? 46.298 66.885 35.208 1.00 74.83 ? 201 LYS A O 1 ATOM 1627 C CB . LYS A 1 201 ? 48.796 68.625 36.210 1.00 83.70 ? 201 LYS A CB 1 ATOM 1628 C CG . LYS A 1 201 ? 48.606 69.944 35.465 1.00 85.26 ? 201 LYS A CG 1 ATOM 1629 C CD . LYS A 1 201 ? 49.894 70.457 34.834 1.00 85.50 ? 201 LYS A CD 1 ATOM 1630 C CE . LYS A 1 201 ? 50.818 71.081 35.861 1.00 87.71 ? 201 LYS A CE 1 ATOM 1631 N NZ . LYS A 1 201 ? 51.999 71.706 35.208 1.00 89.47 ? 201 LYS A NZ 1 ATOM 1632 N N . LYS A 1 202 ? 45.583 68.971 35.660 1.00 82.34 ? 202 LYS A N 1 ATOM 1633 C CA . LYS A 1 202 ? 44.483 68.909 34.703 1.00 80.80 ? 202 LYS A CA 1 ATOM 1634 C C . LYS A 1 202 ? 44.519 70.071 33.711 1.00 75.55 ? 202 LYS A C 1 ATOM 1635 O O . LYS A 1 202 ? 44.695 71.233 34.095 1.00 66.83 ? 202 LYS A O 1 ATOM 1636 C CB . LYS A 1 202 ? 43.153 68.900 35.458 1.00 97.61 ? 202 LYS A CB 1 ATOM 1637 C CG . LYS A 1 202 ? 43.028 67.747 36.445 1.00 103.19 ? 202 LYS A CG 1 ATOM 1638 C CD . LYS A 1 202 ? 41.781 67.872 37.310 1.00 111.11 ? 202 LYS A CD 1 ATOM 1639 C CE . LYS A 1 202 ? 41.706 66.746 38.330 1.00 111.12 ? 202 LYS A CE 1 ATOM 1640 N NZ . LYS A 1 202 ? 40.551 66.919 39.248 1.00 116.97 ? 202 LYS A NZ 1 ATOM 1641 N N . LEU A 1 203 ? 44.344 69.747 32.432 1.00 59.86 ? 203 LEU A N 1 ATOM 1642 C CA . LEU A 1 203 ? 44.371 70.750 31.369 1.00 62.31 ? 203 LEU A CA 1 ATOM 1643 C C . LEU A 1 203 ? 42.979 71.060 30.817 1.00 59.31 ? 203 LEU A C 1 ATOM 1644 O O . LEU A 1 203 ? 42.303 70.181 30.275 1.00 54.88 ? 203 LEU A O 1 ATOM 1645 C CB . LEU A 1 203 ? 45.259 70.270 30.219 1.00 40.68 ? 203 LEU A CB 1 ATOM 1646 C CG . LEU A 1 203 ? 46.583 69.592 30.572 1.00 44.14 ? 203 LEU A CG 1 ATOM 1647 C CD1 . LEU A 1 203 ? 47.315 69.231 29.284 1.00 40.74 ? 203 LEU A CD1 1 ATOM 1648 C CD2 . LEU A 1 203 ? 47.423 70.507 31.455 1.00 37.81 ? 203 LEU A CD2 1 ATOM 1649 N N . LYS A 1 204 ? 42.569 72.320 30.940 1.00 36.89 ? 204 LYS A N 1 ATOM 1650 C CA . LYS A 1 204 ? 41.268 72.762 30.455 1.00 33.38 ? 204 LYS A CA 1 ATOM 1651 C C . LYS A 1 204 ? 41.379 73.573 29.161 1.00 36.14 ? 204 LYS A C 1 ATOM 1652 O O . LYS A 1 204 ? 42.053 74.595 29.107 1.00 37.18 ? 204 LYS A O 1 ATOM 1653 C CB . LYS A 1 204 ? 40.578 73.602 31.535 1.00 33.84 ? 204 LYS A CB 1 ATOM 1654 C CG . LYS A 1 204 ? 39.159 74.042 31.209 1.00 41.68 ? 204 LYS A CG 1 ATOM 1655 C CD . LYS A 1 204 ? 38.544 74.740 32.410 1.00 45.65 ? 204 LYS A CD 1 ATOM 1656 C CE . LYS A 1 204 ? 37.117 75.171 32.143 1.00 60.56 ? 204 LYS A CE 1 ATOM 1657 N NZ . LYS A 1 204 ? 36.489 75.799 33.341 1.00 58.34 ? 204 LYS A NZ 1 ATOM 1658 N N . CYS A 1 205 ? 40.716 73.098 28.116 1.00 32.39 ? 205 CYS A N 1 ATOM 1659 C CA . CYS A 1 205 ? 40.705 73.782 26.832 1.00 32.26 ? 205 CYS A CA 1 ATOM 1660 C C . CYS A 1 205 ? 39.305 74.305 26.614 1.00 32.37 ? 205 CYS A C 1 ATOM 1661 O O . CYS A 1 205 ? 38.374 73.527 26.400 1.00 31.45 ? 205 CYS A O 1 ATOM 1662 C CB . CYS A 1 205 ? 41.020 72.833 25.698 1.00 34.19 ? 205 CYS A CB 1 ATOM 1663 S SG . CYS A 1 205 ? 40.946 73.716 24.123 1.00 54.12 ? 205 CYS A SG 1 ATOM 1664 N N . LEU A 1 206 ? 39.161 75.622 26.651 1.00 26.96 ? 206 LEU A N 1 ATOM 1665 C CA . LEU A 1 206 ? 37.860 76.248 26.491 1.00 20.62 ? 206 LEU A CA 1 ATOM 1666 C C . LEU A 1 206 ? 37.681 76.946 25.158 1.00 30.29 ? 206 LEU A C 1 ATOM 1667 O O . LEU A 1 206 ? 38.578 77.628 24.688 1.00 23.93 ? 206 LEU A O 1 ATOM 1668 C CB . LEU A 1 206 ? 37.639 77.252 27.626 1.00 5.97 ? 206 LEU A CB 1 ATOM 1669 C CG . LEU A 1 206 ? 36.440 78.184 27.495 1.00 10.91 ? 206 LEU A CG 1 ATOM 1670 C CD1 . LEU A 1 206 ? 35.166 77.371 27.441 1.00 20.08 ? 206 LEU A CD1 1 ATOM 1671 C CD2 . LEU A 1 206 ? 36.416 79.151 28.651 1.00 11.23 ? 206 LEU A CD2 1 ATOM 1672 N N . ALA A 1 207 ? 36.514 76.760 24.553 1.00 17.87 ? 207 ALA A N 1 ATOM 1673 C CA . ALA A 1 207 ? 36.172 77.410 23.291 1.00 17.50 ? 207 ALA A CA 1 ATOM 1674 C C . ALA A 1 207 ? 34.992 78.346 23.604 1.00 22.41 ? 207 ALA A C 1 ATOM 1675 O O . ALA A 1 207 ? 33.905 77.884 23.930 1.00 22.92 ? 207 ALA A O 1 ATOM 1676 C CB . ALA A 1 207 ? 35.777 76.370 22.269 1.00 4.65 ? 207 ALA A CB 1 ATOM 1677 N N . TYR A 1 208 ? 35.208 79.656 23.525 1.00 8.03 ? 208 TYR A N 1 ATOM 1678 C CA . TYR A 1 208 ? 34.152 80.622 23.849 1.00 8.03 ? 208 TYR A CA 1 ATOM 1679 C C . TYR A 1 208 ? 33.769 81.611 22.768 1.00 8.03 ? 208 TYR A C 1 ATOM 1680 O O . TYR A 1 208 ? 34.419 81.715 21.747 1.00 8.30 ? 208 TYR A O 1 ATOM 1681 C CB . TYR A 1 208 ? 34.515 81.408 25.112 1.00 19.76 ? 208 TYR A CB 1 ATOM 1682 C CG . TYR A 1 208 ? 35.769 82.249 25.010 1.00 24.45 ? 208 TYR A CG 1 ATOM 1683 C CD1 . TYR A 1 208 ? 37.002 81.678 24.695 1.00 30.25 ? 208 TYR A CD1 1 ATOM 1684 C CD2 . TYR A 1 208 ? 35.728 83.612 25.259 1.00 27.59 ? 208 TYR A CD2 1 ATOM 1685 C CE1 . TYR A 1 208 ? 38.157 82.449 24.633 1.00 31.84 ? 208 TYR A CE1 1 ATOM 1686 C CE2 . TYR A 1 208 ? 36.878 84.389 25.205 1.00 25.91 ? 208 TYR A CE2 1 ATOM 1687 C CZ . TYR A 1 208 ? 38.087 83.804 24.893 1.00 40.00 ? 208 TYR A CZ 1 ATOM 1688 O OH . TYR A 1 208 ? 39.218 84.585 24.861 1.00 48.12 ? 208 TYR A OH 1 ATOM 1689 N N . ASP A 1 209 ? 32.691 82.335 23.015 1.00 16.73 ? 209 ASP A N 1 ATOM 1690 C CA . ASP A 1 209 ? 32.188 83.333 22.084 1.00 21.28 ? 209 ASP A CA 1 ATOM 1691 C C . ASP A 1 209 ? 31.939 82.860 20.658 1.00 25.53 ? 209 ASP A C 1 ATOM 1692 O O . ASP A 1 209 ? 32.280 83.567 19.721 1.00 21.77 ? 209 ASP A O 1 ATOM 1693 C CB . ASP A 1 209 ? 33.128 84.546 22.032 1.00 25.36 ? 209 ASP A CB 1 ATOM 1694 C CG . ASP A 1 209 ? 33.197 85.298 23.346 1.00 27.39 ? 209 ASP A CG 1 ATOM 1695 O OD1 . ASP A 1 209 ? 32.166 85.379 24.055 1.00 25.94 ? 209 ASP A OD1 1 ATOM 1696 O OD2 . ASP A 1 209 ? 34.289 85.821 23.654 1.00 34.20 ? 209 ASP A OD2 1 ATOM 1697 N N . PHE A 1 210 ? 31.346 81.688 20.474 1.00 11.70 ? 210 PHE A N 1 ATOM 1698 C CA . PHE A 1 210 ? 31.073 81.220 19.116 1.00 11.70 ? 210 PHE A CA 1 ATOM 1699 C C . PHE A 1 210 ? 29.591 80.939 18.869 1.00 11.70 ? 210 PHE A C 1 ATOM 1700 O O . PHE A 1 210 ? 28.789 80.925 19.802 1.00 11.70 ? 210 PHE A O 1 ATOM 1701 C CB . PHE A 1 210 ? 31.904 79.977 18.802 1.00 29.51 ? 210 PHE A CB 1 ATOM 1702 C CG . PHE A 1 210 ? 31.565 78.784 19.647 1.00 36.77 ? 210 PHE A CG 1 ATOM 1703 C CD1 . PHE A 1 210 ? 30.513 77.943 19.300 1.00 29.51 ? 210 PHE A CD1 1 ATOM 1704 C CD2 . PHE A 1 210 ? 32.309 78.490 20.787 1.00 29.51 ? 210 PHE A CD2 1 ATOM 1705 C CE1 . PHE A 1 210 ? 30.210 76.826 20.073 1.00 29.51 ? 210 PHE A CE1 1 ATOM 1706 C CE2 . PHE A 1 210 ? 32.011 77.374 21.566 1.00 33.80 ? 210 PHE A CE2 1 ATOM 1707 C CZ . PHE A 1 210 ? 30.962 76.543 21.207 1.00 29.51 ? 210 PHE A CZ 1 ATOM 1708 N N . TYR A 1 211 ? 29.239 80.730 17.602 1.00 17.71 ? 211 TYR A N 1 ATOM 1709 C CA . TYR A 1 211 ? 27.862 80.459 17.188 1.00 17.71 ? 211 TYR A CA 1 ATOM 1710 C C . TYR A 1 211 ? 27.897 80.089 15.725 1.00 17.71 ? 211 TYR A C 1 ATOM 1711 O O . TYR A 1 211 ? 28.554 80.768 14.950 1.00 20.53 ? 211 TYR A O 1 ATOM 1712 C CB . TYR A 1 211 ? 26.995 81.710 17.335 1.00 19.20 ? 211 TYR A CB 1 ATOM 1713 C CG . TYR A 1 211 ? 25.521 81.467 17.082 1.00 19.20 ? 211 TYR A CG 1 ATOM 1714 C CD1 . TYR A 1 211 ? 24.664 81.136 18.121 1.00 19.20 ? 211 TYR A CD1 1 ATOM 1715 C CD2 . TYR A 1 211 ? 24.995 81.533 15.797 1.00 19.20 ? 211 TYR A CD2 1 ATOM 1716 C CE1 . TYR A 1 211 ? 23.318 80.873 17.886 1.00 19.20 ? 211 TYR A CE1 1 ATOM 1717 C CE2 . TYR A 1 211 ? 23.653 81.270 15.548 1.00 21.64 ? 211 TYR A CE2 1 ATOM 1718 C CZ . TYR A 1 211 ? 22.818 80.937 16.598 1.00 19.29 ? 211 TYR A CZ 1 ATOM 1719 O OH . TYR A 1 211 ? 21.494 80.633 16.362 1.00 19.20 ? 211 TYR A OH 1 ATOM 1720 N N . PRO A 1 212 ? 27.174 79.035 15.306 1.00 31.33 ? 212 PRO A N 1 ATOM 1721 C CA . PRO A 1 212 ? 26.291 78.084 15.987 1.00 31.33 ? 212 PRO A CA 1 ATOM 1722 C C . PRO A 1 212 ? 26.963 77.310 17.111 1.00 32.83 ? 212 PRO A C 1 ATOM 1723 O O . PRO A 1 212 ? 28.167 77.440 17.325 1.00 31.33 ? 212 PRO A O 1 ATOM 1724 C CB . PRO A 1 212 ? 25.844 77.172 14.856 1.00 36.50 ? 212 PRO A CB 1 ATOM 1725 C CG . PRO A 1 212 ? 25.822 78.084 13.698 1.00 48.20 ? 212 PRO A CG 1 ATOM 1726 C CD . PRO A 1 212 ? 27.135 78.789 13.856 1.00 36.50 ? 212 PRO A CD 1 ATOM 1727 N N . GLY A 1 213 ? 26.180 76.491 17.809 1.00 17.78 ? 213 GLY A N 1 ATOM 1728 C CA . GLY A 1 213 ? 26.706 75.736 18.931 1.00 16.97 ? 213 GLY A CA 1 ATOM 1729 C C . GLY A 1 213 ? 27.435 74.451 18.601 1.00 16.97 ? 213 GLY A C 1 ATOM 1730 O O . GLY A 1 213 ? 28.249 73.982 19.391 1.00 19.23 ? 213 GLY A O 1 ATOM 1731 N N . LYS A 1 214 ? 27.134 73.869 17.447 1.00 20.44 ? 214 LYS A N 1 ATOM 1732 C CA . LYS A 1 214 ? 27.780 72.631 17.037 1.00 21.44 ? 214 LYS A CA 1 ATOM 1733 C C . LYS A 1 214 ? 29.282 72.900 16.872 1.00 24.43 ? 214 LYS A C 1 ATOM 1734 O O . LYS A 1 214 ? 29.722 73.570 15.932 1.00 20.33 ? 214 LYS A O 1 ATOM 1735 C CB . LYS A 1 214 ? 27.138 72.135 15.731 1.00 46.95 ? 214 LYS A CB 1 ATOM 1736 C CG . LYS A 1 214 ? 27.850 70.990 15.019 1.00 62.09 ? 214 LYS A CG 1 ATOM 1737 C CD . LYS A 1 214 ? 27.743 69.673 15.770 1.00 74.42 ? 214 LYS A CD 1 ATOM 1738 C CE . LYS A 1 214 ? 28.417 68.540 14.997 1.00 79.25 ? 214 LYS A CE 1 ATOM 1739 N NZ . LYS A 1 214 ? 27.790 68.303 13.663 1.00 86.59 ? 214 LYS A NZ 1 ATOM 1740 N N . ILE A 1 215 ? 30.066 72.389 17.812 1.00 30.72 ? 215 ILE A N 1 ATOM 1741 C CA . ILE A 1 215 ? 31.511 72.568 17.791 1.00 33.71 ? 215 ILE A CA 1 ATOM 1742 C C . ILE A 1 215 ? 32.182 71.228 18.030 1.00 41.23 ? 215 ILE A C 1 ATOM 1743 O O . ILE A 1 215 ? 31.537 70.258 18.412 1.00 32.64 ? 215 ILE A O 1 ATOM 1744 C CB . ILE A 1 215 ? 31.970 73.532 18.908 1.00 17.44 ? 215 ILE A CB 1 ATOM 1745 C CG1 . ILE A 1 215 ? 33.336 74.127 18.572 1.00 21.82 ? 215 ILE A CG1 1 ATOM 1746 C CG2 . ILE A 1 215 ? 32.096 72.788 20.212 1.00 18.77 ? 215 ILE A CG2 1 ATOM 1747 C CD1 . ILE A 1 215 ? 33.769 75.242 19.499 1.00 15.37 ? 215 ILE A CD1 1 ATOM 1748 N N . ASP A 1 216 ? 33.484 71.179 17.803 1.00 34.22 ? 216 ASP A N 1 ATOM 1749 C CA . ASP A 1 216 ? 34.254 69.970 18.025 1.00 28.52 ? 216 ASP A CA 1 ATOM 1750 C C . ASP A 1 216 ? 35.532 70.387 18.739 1.00 35.21 ? 216 ASP A C 1 ATOM 1751 O O . ASP A 1 216 ? 36.440 70.951 18.130 1.00 35.10 ? 216 ASP A O 1 ATOM 1752 C CB . ASP A 1 216 ? 34.577 69.286 16.699 1.00 70.13 ? 216 ASP A CB 1 ATOM 1753 C CG . ASP A 1 216 ? 35.261 67.949 16.890 1.00 87.26 ? 216 ASP A CG 1 ATOM 1754 O OD1 . ASP A 1 216 ? 36.428 67.933 17.330 1.00 89.54 ? 216 ASP A OD1 1 ATOM 1755 O OD2 . ASP A 1 216 ? 34.628 66.911 16.608 1.00 92.27 ? 216 ASP A OD2 1 ATOM 1756 N N . VAL A 1 217 ? 35.578 70.114 20.039 1.00 18.57 ? 217 VAL A N 1 ATOM 1757 C CA . VAL A 1 217 ? 36.719 70.452 20.881 1.00 27.18 ? 217 VAL A CA 1 ATOM 1758 C C . VAL A 1 217 ? 37.364 69.214 21.502 1.00 36.08 ? 217 VAL A C 1 ATOM 1759 O O . VAL A 1 217 ? 36.722 68.509 22.278 1.00 35.31 ? 217 VAL A O 1 ATOM 1760 C CB . VAL A 1 217 ? 36.275 71.363 22.038 1.00 12.71 ? 217 VAL A CB 1 ATOM 1761 C CG1 . VAL A 1 217 ? 37.478 71.877 22.803 1.00 13.81 ? 217 VAL A CG1 1 ATOM 1762 C CG2 . VAL A 1 217 ? 35.436 72.489 21.506 1.00 13.83 ? 217 VAL A CG2 1 ATOM 1763 N N . HIS A 1 218 ? 38.625 68.945 21.176 1.00 34.78 ? 218 HIS A N 1 ATOM 1764 C CA . HIS A 1 218 ? 39.302 67.799 21.778 1.00 38.45 ? 218 HIS A CA 1 ATOM 1765 C C . HIS A 1 218 ? 40.805 67.989 21.958 1.00 40.88 ? 218 HIS A C 1 ATOM 1766 O O . HIS A 1 218 ? 41.424 68.783 21.249 1.00 40.63 ? 218 HIS A O 1 ATOM 1767 C CB . HIS A 1 218 ? 39.041 66.528 20.964 1.00 36.47 ? 218 HIS A CB 1 ATOM 1768 C CG . HIS A 1 218 ? 39.771 66.474 19.660 1.00 42.91 ? 218 HIS A CG 1 ATOM 1769 N ND1 . HIS A 1 218 ? 39.127 66.547 18.444 1.00 44.68 ? 218 HIS A ND1 1 ATOM 1770 C CD2 . HIS A 1 218 ? 41.086 66.318 19.380 1.00 46.37 ? 218 HIS A CD2 1 ATOM 1771 C CE1 . HIS A 1 218 ? 40.013 66.438 17.471 1.00 40.60 ? 218 HIS A CE1 1 ATOM 1772 N NE2 . HIS A 1 218 ? 41.210 66.297 18.012 1.00 47.26 ? 218 HIS A NE2 1 ATOM 1773 N N . TRP A 1 219 ? 41.382 67.271 22.927 1.00 44.79 ? 219 TRP A N 1 ATOM 1774 C CA . TRP A 1 219 ? 42.826 67.325 23.177 1.00 43.74 ? 219 TRP A CA 1 ATOM 1775 C C . TRP A 1 219 ? 43.506 66.177 22.447 1.00 46.55 ? 219 TRP A C 1 ATOM 1776 O O . TRP A 1 219 ? 42.856 65.295 21.883 1.00 47.38 ? 219 TRP A O 1 ATOM 1777 C CB . TRP A 1 219 ? 43.181 67.143 24.652 1.00 33.27 ? 219 TRP A CB 1 ATOM 1778 C CG . TRP A 1 219 ? 42.922 68.276 25.551 1.00 36.26 ? 219 TRP A CG 1 ATOM 1779 C CD1 . TRP A 1 219 ? 41.821 68.460 26.324 1.00 28.35 ? 219 TRP A CD1 1 ATOM 1780 C CD2 . TRP A 1 219 ? 43.813 69.355 25.857 1.00 35.56 ? 219 TRP A CD2 1 ATOM 1781 N NE1 . TRP A 1 219 ? 41.968 69.584 27.107 1.00 32.89 ? 219 TRP A NE1 1 ATOM 1782 C CE2 . TRP A 1 219 ? 43.185 70.152 26.837 1.00 33.53 ? 219 TRP A CE2 1 ATOM 1783 C CE3 . TRP A 1 219 ? 45.083 69.724 25.403 1.00 39.85 ? 219 TRP A CE3 1 ATOM 1784 C CZ2 . TRP A 1 219 ? 43.783 71.297 27.374 1.00 38.09 ? 219 TRP A CZ2 1 ATOM 1785 C CZ3 . TRP A 1 219 ? 45.678 70.866 25.944 1.00 29.97 ? 219 TRP A CZ3 1 ATOM 1786 C CH2 . TRP A 1 219 ? 45.025 71.634 26.917 1.00 34.63 ? 219 TRP A CH2 1 ATOM 1787 N N . THR A 1 220 ? 44.831 66.202 22.475 1.00 40.87 ? 220 THR A N 1 ATOM 1788 C CA . THR A 1 220 ? 45.640 65.156 21.878 1.00 42.78 ? 220 THR A CA 1 ATOM 1789 C C . THR A 1 220 ? 46.882 65.074 22.737 1.00 44.71 ? 220 THR A C 1 ATOM 1790 O O . THR A 1 220 ? 47.219 66.020 23.452 1.00 42.20 ? 220 THR A O 1 ATOM 1791 C CB . THR A 1 220 ? 46.053 65.460 20.412 1.00 48.33 ? 220 THR A CB 1 ATOM 1792 O OG1 . THR A 1 220 ? 46.820 66.667 20.357 1.00 49.35 ? 220 THR A OG1 1 ATOM 1793 C CG2 . THR A 1 220 ? 44.829 65.598 19.536 1.00 53.27 ? 220 THR A CG2 1 ATOM 1794 N N . ARG A 1 221 ? 47.542 63.928 22.692 1.00 88.28 ? 221 ARG A N 1 ATOM 1795 C CA . ARG A 1 221 ? 48.758 63.730 23.452 1.00 91.08 ? 221 ARG A CA 1 ATOM 1796 C C . ARG A 1 221 ? 49.738 63.086 22.492 1.00 91.63 ? 221 ARG A C 1 ATOM 1797 O O . ARG A 1 221 ? 49.720 61.872 22.302 1.00 91.45 ? 221 ARG A O 1 ATOM 1798 C CB . ARG A 1 221 ? 48.492 62.817 24.648 1.00 72.76 ? 221 ARG A CB 1 ATOM 1799 C CG . ARG A 1 221 ? 49.702 62.608 25.530 1.00 75.87 ? 221 ARG A CG 1 ATOM 1800 C CD . ARG A 1 221 ? 49.376 61.786 26.767 1.00 78.42 ? 221 ARG A CD 1 ATOM 1801 N NE . ARG A 1 221 ? 50.599 61.315 27.414 1.00 75.47 ? 221 ARG A NE 1 ATOM 1802 C CZ . ARG A 1 221 ? 51.423 60.416 26.883 1.00 75.16 ? 221 ARG A CZ 1 ATOM 1803 N NH1 . ARG A 1 221 ? 51.158 59.881 25.696 1.00 75.16 ? 221 ARG A NH1 1 ATOM 1804 N NH2 . ARG A 1 221 ? 52.521 60.059 27.535 1.00 76.76 ? 221 ARG A NH2 1 ATOM 1805 N N . ALA A 1 222 ? 50.577 63.915 21.874 1.00 69.45 ? 222 ALA A N 1 ATOM 1806 C CA . ALA A 1 222 ? 51.561 63.446 20.905 1.00 69.80 ? 222 ALA A CA 1 ATOM 1807 C C . ALA A 1 222 ? 50.859 62.896 19.673 1.00 68.60 ? 222 ALA A C 1 ATOM 1808 O O . ALA A 1 222 ? 51.291 61.897 19.100 1.00 69.07 ? 222 ALA A O 1 ATOM 1809 C CB . ALA A 1 222 ? 52.453 62.368 21.519 1.00 38.92 ? 222 ALA A CB 1 ATOM 1810 N N . GLY A 1 223 ? 49.765 63.542 19.281 1.00 89.13 ? 223 GLY A N 1 ATOM 1811 C CA . GLY A 1 223 ? 49.033 63.108 18.106 1.00 87.97 ? 223 GLY A CA 1 ATOM 1812 C C . GLY A 1 223 ? 47.863 62.176 18.361 1.00 92.52 ? 223 GLY A C 1 ATOM 1813 O O . GLY A 1 223 ? 47.024 61.986 17.479 1.00 93.26 ? 223 GLY A O 1 ATOM 1814 N N . GLU A 1 224 ? 47.796 61.598 19.557 1.00 76.61 ? 224 GLU A N 1 ATOM 1815 C CA . GLU A 1 224 ? 46.714 60.675 19.900 1.00 79.90 ? 224 GLU A CA 1 ATOM 1816 C C . GLU A 1 224 ? 45.561 61.368 20.627 1.00 75.64 ? 224 GLU A C 1 ATOM 1817 O O . GLU A 1 224 ? 45.718 61.834 21.758 1.00 71.85 ? 224 GLU A O 1 ATOM 1818 C CB . GLU A 1 224 ? 47.247 59.532 20.776 1.00 93.11 ? 224 GLU A CB 1 ATOM 1819 C CG . GLU A 1 224 ? 48.284 58.639 20.108 1.00 100.17 ? 224 GLU A CG 1 ATOM 1820 C CD . GLU A 1 224 ? 47.689 57.730 19.051 1.00 102.57 ? 224 GLU A CD 1 ATOM 1821 O OE1 . GLU A 1 224 ? 46.901 56.832 19.409 1.00 103.26 ? 224 GLU A OE1 1 ATOM 1822 O OE2 . GLU A 1 224 ? 48.009 57.915 17.859 1.00 100.61 ? 224 GLU A OE2 1 ATOM 1823 N N . VAL A 1 225 ? 44.404 61.430 19.971 1.00 57.52 ? 225 VAL A N 1 ATOM 1824 C CA . VAL A 1 225 ? 43.220 62.048 20.558 1.00 58.62 ? 225 VAL A CA 1 ATOM 1825 C C . VAL A 1 225 ? 42.924 61.418 21.918 1.00 54.62 ? 225 VAL A C 1 ATOM 1826 O O . VAL A 1 225 ? 42.544 60.252 22.007 1.00 52.89 ? 225 VAL A O 1 ATOM 1827 C CB . VAL A 1 225 ? 41.994 61.880 19.631 1.00 63.18 ? 225 VAL A CB 1 ATOM 1828 C CG1 . VAL A 1 225 ? 41.936 60.459 19.101 1.00 67.54 ? 225 VAL A CG1 1 ATOM 1829 C CG2 . VAL A 1 225 ? 40.716 62.210 20.387 1.00 59.36 ? 225 VAL A CG2 1 ATOM 1830 N N . GLN A 1 226 ? 43.107 62.205 22.971 1.00 51.48 ? 226 GLN A N 1 ATOM 1831 C CA . GLN A 1 226 ? 42.888 61.755 24.341 1.00 53.78 ? 226 GLN A CA 1 ATOM 1832 C C . GLN A 1 226 ? 41.425 61.725 24.750 1.00 58.23 ? 226 GLN A C 1 ATOM 1833 O O . GLN A 1 226 ? 40.595 62.435 24.188 1.00 60.78 ? 226 GLN A O 1 ATOM 1834 C CB . GLN A 1 226 ? 43.658 62.654 25.310 1.00 72.62 ? 226 GLN A CB 1 ATOM 1835 C CG . GLN A 1 226 ? 45.160 62.556 25.160 1.00 76.45 ? 226 GLN A CG 1 ATOM 1836 C CD . GLN A 1 226 ? 45.685 61.188 25.536 1.00 70.53 ? 226 GLN A CD 1 ATOM 1837 O OE1 . GLN A 1 226 ? 45.808 60.861 26.719 1.00 70.51 ? 226 GLN A OE1 1 ATOM 1838 N NE2 . GLN A 1 226 ? 45.985 60.373 24.530 1.00 65.11 ? 226 GLN A NE2 1 ATOM 1839 N N . GLU A 1 227 ? 41.122 60.892 25.741 1.00 71.49 ? 227 GLU A N 1 ATOM 1840 C CA . GLU A 1 227 ? 39.766 60.757 26.259 1.00 66.39 ? 227 GLU A CA 1 ATOM 1841 C C . GLU A 1 227 ? 39.577 61.818 27.339 1.00 57.53 ? 227 GLU A C 1 ATOM 1842 O O . GLU A 1 227 ? 40.378 61.925 28.267 1.00 57.46 ? 227 GLU A O 1 ATOM 1843 C CB . GLU A 1 227 ? 39.567 59.361 26.854 1.00 127.77 ? 227 GLU A CB 1 ATOM 1844 C CG . GLU A 1 227 ? 38.113 58.980 27.056 1.00 139.41 ? 227 GLU A CG 1 ATOM 1845 C CD . GLU A 1 227 ? 37.341 58.944 25.750 1.00 144.57 ? 227 GLU A CD 1 ATOM 1846 O OE1 . GLU A 1 227 ? 37.727 58.169 24.849 1.00 145.66 ? 227 GLU A OE1 1 ATOM 1847 O OE2 . GLU A 1 227 ? 36.350 59.692 25.624 1.00 148.43 ? 227 GLU A OE2 1 ATOM 1848 N N . PRO A 1 228 ? 38.515 62.621 27.231 1.00 43.34 ? 228 PRO A N 1 ATOM 1849 C CA . PRO A 1 228 ? 38.285 63.663 28.232 1.00 42.15 ? 228 PRO A CA 1 ATOM 1850 C C . PRO A 1 228 ? 37.760 63.162 29.575 1.00 42.77 ? 228 PRO A C 1 ATOM 1851 O O . PRO A 1 228 ? 37.021 62.180 29.647 1.00 42.85 ? 228 PRO A O 1 ATOM 1852 C CB . PRO A 1 228 ? 37.312 64.607 27.525 1.00 39.44 ? 228 PRO A CB 1 ATOM 1853 C CG . PRO A 1 228 ? 36.509 63.683 26.680 1.00 34.88 ? 228 PRO A CG 1 ATOM 1854 C CD . PRO A 1 228 ? 37.532 62.707 26.135 1.00 38.65 ? 228 PRO A CD 1 ATOM 1855 N N . GLU A 1 229 ? 38.174 63.854 30.632 1.00 34.47 ? 229 GLU A N 1 ATOM 1856 C CA . GLU A 1 229 ? 37.789 63.559 32.005 1.00 33.75 ? 229 GLU A CA 1 ATOM 1857 C C . GLU A 1 229 ? 36.500 64.312 32.291 1.00 42.00 ? 229 GLU A C 1 ATOM 1858 O O . GLU A 1 229 ? 35.566 63.760 32.862 1.00 43.92 ? 229 GLU A O 1 ATOM 1859 C CB . GLU A 1 229 ? 38.905 64.013 32.949 1.00 51.31 ? 229 GLU A CB 1 ATOM 1860 C CG . GLU A 1 229 ? 38.590 63.925 34.422 1.00 58.36 ? 229 GLU A CG 1 ATOM 1861 C CD . GLU A 1 229 ? 39.818 64.152 35.291 1.00 64.14 ? 229 GLU A CD 1 ATOM 1862 O OE1 . GLU A 1 229 ? 40.720 63.283 35.273 1.00 64.18 ? 229 GLU A OE1 1 ATOM 1863 O OE2 . GLU A 1 229 ? 39.884 65.193 35.985 1.00 62.19 ? 229 GLU A OE2 1 ATOM 1864 N N . LEU A 1 230 ? 36.458 65.577 31.888 1.00 71.58 ? 230 LEU A N 1 ATOM 1865 C CA . LEU A 1 230 ? 35.278 66.420 32.056 1.00 70.01 ? 230 LEU A CA 1 ATOM 1866 C C . LEU A 1 230 ? 34.956 67.074 30.730 1.00 74.91 ? 230 LEU A C 1 ATOM 1867 O O . LEU A 1 230 ? 35.849 67.534 30.028 1.00 75.28 ? 230 LEU A O 1 ATOM 1868 C CB . LEU A 1 230 ? 35.508 67.532 33.084 1.00 54.44 ? 230 LEU A CB 1 ATOM 1869 C CG . LEU A 1 230 ? 35.325 67.248 34.573 1.00 62.79 ? 230 LEU A CG 1 ATOM 1870 C CD1 . LEU A 1 230 ? 36.440 66.348 35.083 1.00 68.72 ? 230 LEU A CD1 1 ATOM 1871 C CD2 . LEU A 1 230 ? 35.322 68.569 35.323 1.00 58.23 ? 230 LEU A CD2 1 ATOM 1872 N N . ARG A 1 231 ? 33.677 67.110 30.388 1.00 42.82 ? 231 ARG A N 1 ATOM 1873 C CA . ARG A 1 231 ? 33.235 67.736 29.154 1.00 37.87 ? 231 ARG A CA 1 ATOM 1874 C C . ARG A 1 231 ? 32.038 68.603 29.500 1.00 42.38 ? 231 ARG A C 1 ATOM 1875 O O . ARG A 1 231 ? 31.177 68.192 30.279 1.00 35.49 ? 231 ARG A O 1 ATOM 1876 C CB . ARG A 1 231 ? 32.828 66.679 28.128 1.00 74.07 ? 231 ARG A CB 1 ATOM 1877 C CG . ARG A 1 231 ? 32.328 67.262 26.819 1.00 87.28 ? 231 ARG A CG 1 ATOM 1878 C CD . ARG A 1 231 ? 31.792 66.180 25.914 1.00 94.94 ? 231 ARG A CD 1 ATOM 1879 N NE . ARG A 1 231 ? 32.787 65.144 25.676 1.00 103.11 ? 231 ARG A NE 1 ATOM 1880 C CZ . ARG A 1 231 ? 32.586 64.085 24.901 1.00 105.14 ? 231 ARG A CZ 1 ATOM 1881 N NH1 . ARG A 1 231 ? 31.421 63.923 24.289 1.00 102.32 ? 231 ARG A NH1 1 ATOM 1882 N NH2 . ARG A 1 231 ? 33.548 63.188 24.736 1.00 111.11 ? 231 ARG A NH2 1 ATOM 1883 N N . GLY A 1 232 ? 31.978 69.804 28.937 1.00 56.81 ? 232 GLY A N 1 ATOM 1884 C CA . GLY A 1 232 ? 30.857 70.670 29.235 1.00 56.77 ? 232 GLY A CA 1 ATOM 1885 C C . GLY A 1 232 ? 30.621 71.736 28.193 1.00 64.76 ? 232 GLY A C 1 ATOM 1886 O O . GLY A 1 232 ? 31.432 71.917 27.293 1.00 58.26 ? 232 GLY A O 1 ATOM 1887 N N . ASP A 1 233 ? 29.499 72.435 28.314 1.00 16.45 ? 233 ASP A N 1 ATOM 1888 C CA . ASP A 1 233 ? 29.157 73.496 27.389 1.00 8.69 ? 233 ASP A CA 1 ATOM 1889 C C . ASP A 1 233 ? 27.949 74.294 27.855 1.00 14.72 ? 233 ASP A C 1 ATOM 1890 O O . ASP A 1 233 ? 27.190 73.845 28.700 1.00 10.93 ? 233 ASP A O 1 ATOM 1891 C CB . ASP A 1 233 ? 28.928 72.937 25.976 1.00 7.89 ? 233 ASP A CB 1 ATOM 1892 C CG . ASP A 1 233 ? 27.752 71.998 25.882 1.00 12.64 ? 233 ASP A CG 1 ATOM 1893 O OD1 . ASP A 1 233 ? 26.668 72.340 26.384 1.00 18.06 ? 233 ASP A OD1 1 ATOM 1894 O OD2 . ASP A 1 233 ? 27.908 70.926 25.273 1.00 15.73 ? 233 ASP A OD2 1 ATOM 1895 N N . VAL A 1 234 ? 27.764 75.485 27.302 1.00 22.13 ? 234 VAL A N 1 ATOM 1896 C CA . VAL A 1 234 ? 26.657 76.314 27.732 1.00 22.13 ? 234 VAL A CA 1 ATOM 1897 C C . VAL A 1 234 ? 26.246 77.321 26.682 1.00 22.13 ? 234 VAL A C 1 ATOM 1898 O O . VAL A 1 234 ? 26.986 77.575 25.750 1.00 22.13 ? 234 VAL A O 1 ATOM 1899 C CB . VAL A 1 234 ? 27.041 77.079 28.989 1.00 5.10 ? 234 VAL A CB 1 ATOM 1900 C CG1 . VAL A 1 234 ? 28.147 78.052 28.662 1.00 5.10 ? 234 VAL A CG1 1 ATOM 1901 C CG2 . VAL A 1 234 ? 25.841 77.791 29.571 1.00 6.70 ? 234 VAL A CG2 1 ATOM 1902 N N . LEU A 1 235 ? 25.052 77.881 26.847 1.00 13.06 ? 235 LEU A N 1 ATOM 1903 C CA . LEU A 1 235 ? 24.521 78.888 25.941 1.00 13.06 ? 235 LEU A CA 1 ATOM 1904 C C . LEU A 1 235 ? 24.191 80.125 26.746 1.00 13.06 ? 235 LEU A C 1 ATOM 1905 O O . LEU A 1 235 ? 23.517 80.055 27.758 1.00 13.06 ? 235 LEU A O 1 ATOM 1906 C CB . LEU A 1 235 ? 23.243 78.409 25.240 1.00 9.56 ? 235 LEU A CB 1 ATOM 1907 C CG . LEU A 1 235 ? 22.401 79.550 24.648 1.00 9.56 ? 235 LEU A CG 1 ATOM 1908 C CD1 . LEU A 1 235 ? 23.175 80.167 23.514 1.00 9.56 ? 235 LEU A CD1 1 ATOM 1909 C CD2 . LEU A 1 235 ? 21.051 79.073 24.161 1.00 9.56 ? 235 LEU A CD2 1 ATOM 1910 N N . HIS A 1 236 ? 24.683 81.261 26.297 1.00 12.74 ? 236 HIS A N 1 ATOM 1911 C CA . HIS A 1 236 ? 24.404 82.505 26.973 1.00 12.74 ? 236 HIS A CA 1 ATOM 1912 C C . HIS A 1 236 ? 23.456 83.214 26.037 1.00 12.74 ? 236 HIS A C 1 ATOM 1913 O O . HIS A 1 236 ? 23.833 83.596 24.946 1.00 12.74 ? 236 HIS A O 1 ATOM 1914 C CB . HIS A 1 236 ? 25.694 83.287 27.161 1.00 26.92 ? 236 HIS A CB 1 ATOM 1915 C CG . HIS A 1 236 ? 26.659 82.628 28.098 1.00 28.32 ? 236 HIS A CG 1 ATOM 1916 N ND1 . HIS A 1 236 ? 26.433 82.537 29.454 1.00 24.86 ? 236 HIS A ND1 1 ATOM 1917 C CD2 . HIS A 1 236 ? 27.851 82.029 27.875 1.00 26.37 ? 236 HIS A CD2 1 ATOM 1918 C CE1 . HIS A 1 236 ? 27.446 81.915 30.027 1.00 31.83 ? 236 HIS A CE1 1 ATOM 1919 N NE2 . HIS A 1 236 ? 28.320 81.595 29.090 1.00 32.37 ? 236 HIS A NE2 1 ATOM 1920 N N . ASN A 1 237 ? 22.213 83.359 26.457 1.00 11.92 ? 237 ASN A N 1 ATOM 1921 C CA . ASN A 1 237 ? 21.216 83.983 25.620 1.00 12.51 ? 237 ASN A CA 1 ATOM 1922 C C . ASN A 1 237 ? 21.465 85.470 25.461 1.00 11.92 ? 237 ASN A C 1 ATOM 1923 O O . ASN A 1 237 ? 21.169 86.041 24.414 1.00 11.92 ? 237 ASN A O 1 ATOM 1924 C CB . ASN A 1 237 ? 19.829 83.734 26.207 1.00 16.52 ? 237 ASN A CB 1 ATOM 1925 C CG . ASN A 1 237 ? 18.719 84.076 25.244 1.00 16.52 ? 237 ASN A CG 1 ATOM 1926 O OD1 . ASN A 1 237 ? 18.551 83.430 24.217 1.00 16.52 ? 237 ASN A OD1 1 ATOM 1927 N ND2 . ASN A 1 237 ? 17.951 85.104 25.575 1.00 16.52 ? 237 ASN A ND2 1 ATOM 1928 N N . GLY A 1 238 ? 22.006 86.103 26.493 1.00 23.54 ? 238 GLY A N 1 ATOM 1929 C CA . GLY A 1 238 ? 22.272 87.526 26.403 1.00 23.54 ? 238 GLY A CA 1 ATOM 1930 C C . GLY A 1 238 ? 23.100 87.904 25.186 1.00 23.54 ? 238 GLY A C 1 ATOM 1931 O O . GLY A 1 238 ? 22.760 88.837 24.459 1.00 24.87 ? 238 GLY A O 1 ATOM 1932 N N . ASN A 1 239 ? 24.196 87.185 24.966 1.00 19.13 ? 239 ASN A N 1 ATOM 1933 C CA . ASN A 1 239 ? 25.078 87.454 23.843 1.00 25.39 ? 239 ASN A CA 1 ATOM 1934 C C . ASN A 1 239 ? 24.563 86.682 22.655 1.00 20.30 ? 239 ASN A C 1 ATOM 1935 O O . ASN A 1 239 ? 24.510 87.191 21.545 1.00 19.13 ? 239 ASN A O 1 ATOM 1936 C CB . ASN A 1 239 ? 26.508 86.977 24.130 1.00 49.98 ? 239 ASN A CB 1 ATOM 1937 C CG . ASN A 1 239 ? 27.046 87.482 25.449 1.00 61.40 ? 239 ASN A CG 1 ATOM 1938 O OD1 . ASN A 1 239 ? 27.393 88.653 25.600 1.00 85.55 ? 239 ASN A OD1 1 ATOM 1939 N ND2 . ASN A 1 239 ? 27.086 86.580 26.422 1.00 47.62 ? 239 ASN A ND2 1 ATOM 1940 N N . GLY A 1 240 ? 24.179 85.437 22.908 1.00 17.28 ? 240 GLY A N 1 ATOM 1941 C CA . GLY A 1 240 ? 23.715 84.556 21.854 1.00 17.28 ? 240 GLY A CA 1 ATOM 1942 C C . GLY A 1 240 ? 24.949 83.809 21.408 1.00 17.28 ? 240 GLY A C 1 ATOM 1943 O O . GLY A 1 240 ? 25.158 83.600 20.229 1.00 17.28 ? 240 GLY A O 1 ATOM 1944 N N . THR A 1 241 ? 25.772 83.423 22.381 1.00 25.85 ? 241 THR A N 1 ATOM 1945 C CA . THR A 1 241 ? 27.035 82.717 22.146 1.00 25.85 ? 241 THR A CA 1 ATOM 1946 C C . THR A 1 241 ? 27.148 81.439 22.974 1.00 25.85 ? 241 THR A C 1 ATOM 1947 O O . THR A 1 241 ? 26.589 81.335 24.056 1.00 25.85 ? 241 THR A O 1 ATOM 1948 C CB . THR A 1 241 ? 28.248 83.618 22.487 1.00 43.46 ? 241 THR A CB 1 ATOM 1949 O OG1 . THR A 1 241 ? 28.053 84.213 23.774 1.00 41.74 ? 241 THR A OG1 1 ATOM 1950 C CG2 . THR A 1 241 ? 28.410 84.720 21.459 1.00 43.34 ? 241 THR A CG2 1 ATOM 1951 N N . TYR A 1 242 ? 27.871 80.462 22.450 1.00 18.41 ? 242 TYR A N 1 ATOM 1952 C CA . TYR A 1 242 ? 28.051 79.200 23.143 1.00 18.41 ? 242 TYR A CA 1 ATOM 1953 C C . TYR A 1 242 ? 29.451 79.121 23.710 1.00 21.02 ? 242 TYR A C 1 ATOM 1954 O O . TYR A 1 242 ? 30.316 79.883 23.337 1.00 18.41 ? 242 TYR A O 1 ATOM 1955 C CB . TYR A 1 242 ? 27.846 78.019 22.188 1.00 32.24 ? 242 TYR A CB 1 ATOM 1956 C CG . TYR A 1 242 ? 26.407 77.667 21.865 1.00 36.04 ? 242 TYR A CG 1 ATOM 1957 C CD1 . TYR A 1 242 ? 25.669 78.404 20.943 1.00 34.67 ? 242 TYR A CD1 1 ATOM 1958 C CD2 . TYR A 1 242 ? 25.792 76.582 22.477 1.00 32.24 ? 242 TYR A CD2 1 ATOM 1959 C CE1 . TYR A 1 242 ? 24.345 78.057 20.640 1.00 32.24 ? 242 TYR A CE1 1 ATOM 1960 C CE2 . TYR A 1 242 ? 24.483 76.233 22.185 1.00 32.24 ? 242 TYR A CE2 1 ATOM 1961 C CZ . TYR A 1 242 ? 23.762 76.968 21.270 1.00 32.24 ? 242 TYR A CZ 1 ATOM 1962 O OH . TYR A 1 242 ? 22.468 76.605 20.993 1.00 32.24 ? 242 TYR A OH 1 ATOM 1963 N N . GLN A 1 243 ? 29.662 78.185 24.615 1.00 20.72 ? 243 GLN A N 1 ATOM 1964 C CA . GLN A 1 243 ? 30.957 77.970 25.232 1.00 20.72 ? 243 GLN A CA 1 ATOM 1965 C C . GLN A 1 243 ? 31.056 76.466 25.419 1.00 24.39 ? 243 GLN A C 1 ATOM 1966 O O . GLN A 1 243 ? 30.097 75.830 25.839 1.00 22.80 ? 243 GLN A O 1 ATOM 1967 C CB . GLN A 1 243 ? 31.044 78.669 26.588 1.00 12.74 ? 243 GLN A CB 1 ATOM 1968 C CG . GLN A 1 243 ? 31.371 80.137 26.527 1.00 14.73 ? 243 GLN A CG 1 ATOM 1969 C CD . GLN A 1 243 ? 31.619 80.735 27.896 1.00 14.67 ? 243 GLN A CD 1 ATOM 1970 O OE1 . GLN A 1 243 ? 32.367 80.192 28.695 1.00 19.84 ? 243 GLN A OE1 1 ATOM 1971 N NE2 . GLN A 1 243 ? 31.001 81.867 28.165 1.00 16.59 ? 243 GLN A NE2 1 ATOM 1972 N N . SER A 1 244 ? 32.213 75.901 25.102 1.00 22.70 ? 244 SER A N 1 ATOM 1973 C CA . SER A 1 244 ? 32.415 74.469 25.218 1.00 22.02 ? 244 SER A CA 1 ATOM 1974 C C . SER A 1 244 ? 33.839 74.163 25.640 1.00 33.32 ? 244 SER A C 1 ATOM 1975 O O . SER A 1 244 ? 34.790 74.571 24.978 1.00 29.46 ? 244 SER A O 1 ATOM 1976 C CB . SER A 1 244 ? 32.122 73.805 23.876 1.00 42.99 ? 244 SER A CB 1 ATOM 1977 O OG . SER A 1 244 ? 32.396 72.420 23.925 1.00 46.88 ? 244 SER A OG 1 ATOM 1978 N N . TRP A 1 245 ? 33.983 73.436 26.741 1.00 27.15 ? 245 TRP A N 1 ATOM 1979 C CA . TRP A 1 245 ? 35.297 73.076 27.254 1.00 23.89 ? 245 TRP A CA 1 ATOM 1980 C C . TRP A 1 245 ? 35.493 71.567 27.337 1.00 35.85 ? 245 TRP A C 1 ATOM 1981 O O . TRP A 1 245 ? 34.571 70.786 27.112 1.00 28.76 ? 245 TRP A O 1 ATOM 1982 C CB . TRP A 1 245 ? 35.493 73.703 28.634 1.00 26.74 ? 245 TRP A CB 1 ATOM 1983 C CG . TRP A 1 245 ? 34.453 73.298 29.615 1.00 36.39 ? 245 TRP A CG 1 ATOM 1984 C CD1 . TRP A 1 245 ? 34.517 72.264 30.501 1.00 38.60 ? 245 TRP A CD1 1 ATOM 1985 C CD2 . TRP A 1 245 ? 33.156 73.872 29.764 1.00 43.18 ? 245 TRP A CD2 1 ATOM 1986 N NE1 . TRP A 1 245 ? 33.336 72.155 31.192 1.00 39.38 ? 245 TRP A NE1 1 ATOM 1987 C CE2 . TRP A 1 245 ? 32.482 73.132 30.756 1.00 43.48 ? 245 TRP A CE2 1 ATOM 1988 C CE3 . TRP A 1 245 ? 32.493 74.940 29.151 1.00 45.04 ? 245 TRP A CE3 1 ATOM 1989 C CZ2 . TRP A 1 245 ? 31.175 73.425 31.150 1.00 49.16 ? 245 TRP A CZ2 1 ATOM 1990 C CZ3 . TRP A 1 245 ? 31.191 75.233 29.545 1.00 52.61 ? 245 TRP A CZ3 1 ATOM 1991 C CH2 . TRP A 1 245 ? 30.547 74.476 30.535 1.00 50.53 ? 245 TRP A CH2 1 ATOM 1992 N N . VAL A 1 246 ? 36.721 71.175 27.646 1.00 35.03 ? 246 VAL A N 1 ATOM 1993 C CA . VAL A 1 246 ? 37.106 69.776 27.791 1.00 41.92 ? 246 VAL A CA 1 ATOM 1994 C C . VAL A 1 246 ? 38.295 69.729 28.746 1.00 45.56 ? 246 VAL A C 1 ATOM 1995 O O . VAL A 1 246 ? 39.136 70.627 28.743 1.00 40.85 ? 246 VAL A O 1 ATOM 1996 C CB . VAL A 1 246 ? 37.547 69.151 26.457 1.00 10.70 ? 246 VAL A CB 1 ATOM 1997 C CG1 . VAL A 1 246 ? 38.174 67.827 26.727 1.00 19.51 ? 246 VAL A CG1 1 ATOM 1998 C CG2 . VAL A 1 246 ? 36.365 68.969 25.520 1.00 13.06 ? 246 VAL A CG2 1 ATOM 1999 N N . VAL A 1 247 ? 38.370 68.686 29.561 1.00 29.55 ? 247 VAL A N 1 ATOM 2000 C CA . VAL A 1 247 ? 39.473 68.569 30.513 1.00 34.00 ? 247 VAL A CA 1 ATOM 2001 C C . VAL A 1 247 ? 40.111 67.192 30.516 1.00 35.62 ? 247 VAL A C 1 ATOM 2002 O O . VAL A 1 247 ? 39.428 66.187 30.423 1.00 34.95 ? 247 VAL A O 1 ATOM 2003 C CB . VAL A 1 247 ? 39.011 68.878 31.947 1.00 16.43 ? 247 VAL A CB 1 ATOM 2004 C CG1 . VAL A 1 247 ? 40.201 68.845 32.885 1.00 18.17 ? 247 VAL A CG1 1 ATOM 2005 C CG2 . VAL A 1 247 ? 38.318 70.238 31.995 1.00 14.51 ? 247 VAL A CG2 1 ATOM 2006 N N . VAL A 1 248 ? 41.431 67.144 30.612 1.00 66.31 ? 248 VAL A N 1 ATOM 2007 C CA . VAL A 1 248 ? 42.108 65.860 30.640 1.00 65.00 ? 248 VAL A CA 1 ATOM 2008 C C . VAL A 1 248 ? 43.078 65.800 31.797 1.00 67.01 ? 248 VAL A C 1 ATOM 2009 O O . VAL A 1 248 ? 43.616 66.822 32.233 1.00 61.95 ? 248 VAL A O 1 ATOM 2010 C CB . VAL A 1 248 ? 42.877 65.581 29.336 1.00 22.86 ? 248 VAL A CB 1 ATOM 2011 C CG1 . VAL A 1 248 ? 41.906 65.438 28.187 1.00 16.65 ? 248 VAL A CG1 1 ATOM 2012 C CG2 . VAL A 1 248 ? 43.858 66.693 29.067 1.00 18.87 ? 248 VAL A CG2 1 ATOM 2013 N N . ALA A 1 249 ? 43.276 64.589 32.302 1.00 49.61 ? 249 ALA A N 1 ATOM 2014 C CA . ALA A 1 249 ? 44.191 64.363 33.403 1.00 51.74 ? 249 ALA A CA 1 ATOM 2015 C C . ALA A 1 249 ? 45.532 63.971 32.802 1.00 49.36 ? 249 ALA A C 1 ATOM 2016 O O . ALA A 1 249 ? 45.590 63.190 31.849 1.00 40.41 ? 249 ALA A O 1 ATOM 2017 C CB . ALA A 1 249 ? 43.666 63.256 34.298 1.00 69.22 ? 249 ALA A CB 1 ATOM 2018 N N . VAL A 1 250 ? 46.605 64.527 33.354 1.00 43.65 ? 250 VAL A N 1 ATOM 2019 C CA . VAL A 1 250 ? 47.943 64.238 32.864 1.00 53.04 ? 250 VAL A CA 1 ATOM 2020 C C . VAL A 1 250 ? 48.829 63.652 33.971 1.00 51.67 ? 250 VAL A C 1 ATOM 2021 O O . VAL A 1 250 ? 48.990 64.254 35.037 1.00 49.21 ? 250 VAL A O 1 ATOM 2022 C CB . VAL A 1 250 ? 48.598 65.521 32.281 1.00 65.48 ? 250 VAL A CB 1 ATOM 2023 C CG1 . VAL A 1 250 ? 48.767 66.573 33.367 1.00 61.49 ? 250 VAL A CG1 1 ATOM 2024 C CG2 . VAL A 1 250 ? 49.931 65.181 31.651 1.00 65.36 ? 250 VAL A CG2 1 ATOM 2025 N N . PRO A 1 251 ? 49.404 62.456 33.731 1.00 99.84 ? 251 PRO A N 1 ATOM 2026 C CA . PRO A 1 251 ? 50.275 61.787 34.705 1.00 105.55 ? 251 PRO A CA 1 ATOM 2027 C C . PRO A 1 251 ? 51.327 62.738 35.282 1.00 110.48 ? 251 PRO A C 1 ATOM 2028 O O . PRO A 1 251 ? 51.780 63.662 34.605 1.00 109.69 ? 251 PRO A O 1 ATOM 2029 C CB . PRO A 1 251 ? 50.889 60.658 33.888 1.00 65.82 ? 251 PRO A CB 1 ATOM 2030 C CG . PRO A 1 251 ? 49.768 60.284 32.966 1.00 64.39 ? 251 PRO A CG 1 ATOM 2031 C CD . PRO A 1 251 ? 49.249 61.633 32.516 1.00 62.47 ? 251 PRO A CD 1 ATOM 2032 N N . PRO A 1 252 ? 51.738 62.510 36.541 1.00 102.81 ? 252 PRO A N 1 ATOM 2033 C CA . PRO A 1 252 ? 52.734 63.341 37.228 1.00 103.94 ? 252 PRO A CA 1 ATOM 2034 C C . PRO A 1 252 ? 54.109 63.373 36.562 1.00 104.88 ? 252 PRO A C 1 ATOM 2035 O O . PRO A 1 252 ? 54.791 64.399 36.574 1.00 105.21 ? 252 PRO A O 1 ATOM 2036 C CB . PRO A 1 252 ? 52.778 62.731 38.625 1.00 105.94 ? 252 PRO A CB 1 ATOM 2037 C CG . PRO A 1 252 ? 52.528 61.282 38.351 1.00 106.82 ? 252 PRO A CG 1 ATOM 2038 C CD . PRO A 1 252 ? 51.388 61.335 37.360 1.00 105.29 ? 252 PRO A CD 1 ATOM 2039 N N . GLN A 1 253 ? 54.513 62.248 35.982 1.00 85.79 ? 253 GLN A N 1 ATOM 2040 C CA . GLN A 1 253 ? 55.807 62.162 35.322 1.00 88.73 ? 253 GLN A CA 1 ATOM 2041 C C . GLN A 1 253 ? 55.633 61.987 33.812 1.00 88.49 ? 253 GLN A C 1 ATOM 2042 O O . GLN A 1 253 ? 55.991 60.952 33.249 1.00 87.04 ? 253 GLN A O 1 ATOM 2043 C CB . GLN A 1 253 ? 56.609 60.993 35.904 1.00 125.04 ? 253 GLN A CB 1 ATOM 2044 C CG . GLN A 1 253 ? 58.050 60.905 35.418 1.00 127.80 ? 253 GLN A CG 1 ATOM 2045 C CD . GLN A 1 253 ? 58.789 59.712 35.997 1.00 133.48 ? 253 GLN A CD 1 ATOM 2046 O OE1 . GLN A 1 253 ? 58.955 59.598 37.211 1.00 135.09 ? 253 GLN A OE1 1 ATOM 2047 N NE2 . GLN A 1 253 ? 59.236 58.815 35.126 1.00 131.51 ? 253 GLN A NE2 1 ATOM 2048 N N . ASP A 1 254 ? 55.074 63.003 33.163 1.00 112.66 ? 254 ASP A N 1 ATOM 2049 C CA . ASP A 1 254 ? 54.860 62.961 31.720 1.00 111.33 ? 254 ASP A CA 1 ATOM 2050 C C . ASP A 1 254 ? 55.400 64.246 31.109 1.00 107.30 ? 254 ASP A C 1 ATOM 2051 O O . ASP A 1 254 ? 55.250 65.324 31.684 1.00 102.96 ? 254 ASP A O 1 ATOM 2052 C CB . ASP A 1 254 ? 53.368 62.824 31.400 1.00 103.17 ? 254 ASP A CB 1 ATOM 2053 C CG . ASP A 1 254 ? 53.110 62.465 29.943 1.00 104.82 ? 254 ASP A CG 1 ATOM 2054 O OD1 . ASP A 1 254 ? 53.632 63.162 29.048 1.00 107.46 ? 254 ASP A OD1 1 ATOM 2055 O OD2 . ASP A 1 254 ? 52.380 61.486 29.690 1.00 108.86 ? 254 ASP A OD2 1 ATOM 2056 N N . THR A 1 255 ? 56.026 64.128 29.942 1.00 102.42 ? 255 THR A N 1 ATOM 2057 C CA . THR A 1 255 ? 56.594 65.286 29.267 1.00 103.40 ? 255 THR A CA 1 ATOM 2058 C C . THR A 1 255 ? 55.949 65.534 27.910 1.00 99.32 ? 255 THR A C 1 ATOM 2059 O O . THR A 1 255 ? 55.996 66.649 27.391 1.00 99.26 ? 255 THR A O 1 ATOM 2060 C CB . THR A 1 255 ? 58.110 65.112 29.068 1.00 122.96 ? 255 THR A CB 1 ATOM 2061 O OG1 . THR A 1 255 ? 58.731 64.862 30.335 1.00 120.78 ? 255 THR A OG1 1 ATOM 2062 C CG2 . THR A 1 255 ? 58.716 66.367 28.457 1.00 123.51 ? 255 THR A CG2 1 ATOM 2063 N N . ALA A 1 256 ? 55.347 64.490 27.345 1.00 84.46 ? 256 ALA A N 1 ATOM 2064 C CA . ALA A 1 256 ? 54.689 64.573 26.041 1.00 82.84 ? 256 ALA A CA 1 ATOM 2065 C C . ALA A 1 256 ? 53.934 65.887 25.854 1.00 80.97 ? 256 ALA A C 1 ATOM 2066 O O . ALA A 1 256 ? 53.399 66.445 26.809 1.00 69.61 ? 256 ALA A O 1 ATOM 2067 C CB . ALA A 1 256 ? 53.740 63.399 25.863 1.00 66.83 ? 256 ALA A CB 1 ATOM 2068 N N . PRO A 1 257 ? 53.882 66.393 24.611 1.00 109.65 ? 257 PRO A N 1 ATOM 2069 C CA . PRO A 1 257 ? 53.199 67.647 24.272 1.00 108.36 ? 257 PRO A CA 1 ATOM 2070 C C . PRO A 1 257 ? 51.687 67.520 24.058 1.00 106.41 ? 257 PRO A C 1 ATOM 2071 O O . PRO A 1 257 ? 51.229 66.694 23.265 1.00 103.67 ? 257 PRO A O 1 ATOM 2072 C CB . PRO A 1 257 ? 53.919 68.082 23.003 1.00 110.12 ? 257 PRO A CB 1 ATOM 2073 C CG . PRO A 1 257 ? 54.145 66.769 22.313 1.00 112.77 ? 257 PRO A CG 1 ATOM 2074 C CD . PRO A 1 257 ? 54.616 65.867 23.443 1.00 112.56 ? 257 PRO A CD 1 ATOM 2075 N N . TYR A 1 258 ? 50.920 68.350 24.762 1.00 65.01 ? 258 TYR A N 1 ATOM 2076 C CA . TYR A 1 258 ? 49.463 68.339 24.636 1.00 65.13 ? 258 TYR A CA 1 ATOM 2077 C C . TYR A 1 258 ? 48.968 69.496 23.771 1.00 61.39 ? 258 TYR A C 1 ATOM 2078 O O . TYR A 1 258 ? 49.355 70.648 23.973 1.00 60.70 ? 258 TYR A O 1 ATOM 2079 C CB . TYR A 1 258 ? 48.799 68.411 26.015 1.00 99.54 ? 258 TYR A CB 1 ATOM 2080 C CG . TYR A 1 258 ? 48.985 67.165 26.851 1.00 106.96 ? 258 TYR A CG 1 ATOM 2081 C CD1 . TYR A 1 258 ? 50.174 66.931 27.539 1.00 103.57 ? 258 TYR A CD1 1 ATOM 2082 C CD2 . TYR A 1 258 ? 47.980 66.204 26.931 1.00 105.78 ? 258 TYR A CD2 1 ATOM 2083 C CE1 . TYR A 1 258 ? 50.356 65.771 28.287 1.00 107.98 ? 258 TYR A CE1 1 ATOM 2084 C CE2 . TYR A 1 258 ? 48.153 65.042 27.673 1.00 109.20 ? 258 TYR A CE2 1 ATOM 2085 C CZ . TYR A 1 258 ? 49.341 64.832 28.348 1.00 109.13 ? 258 TYR A CZ 1 ATOM 2086 O OH . TYR A 1 258 ? 49.513 63.682 29.082 1.00 107.83 ? 258 TYR A OH 1 ATOM 2087 N N . SER A 1 259 ? 48.101 69.182 22.815 1.00 86.37 ? 259 SER A N 1 ATOM 2088 C CA . SER A 1 259 ? 47.564 70.191 21.910 1.00 88.52 ? 259 SER A CA 1 ATOM 2089 C C . SER A 1 259 ? 46.039 70.129 21.824 1.00 86.21 ? 259 SER A C 1 ATOM 2090 O O . SER A 1 259 ? 45.465 69.052 21.671 1.00 76.68 ? 259 SER A O 1 ATOM 2091 C CB . SER A 1 259 ? 48.163 69.995 20.515 1.00 100.17 ? 259 SER A CB 1 ATOM 2092 O OG . SER A 1 259 ? 49.575 69.876 20.576 1.00 117.21 ? 259 SER A OG 1 ATOM 2093 N N . CYS A 1 260 ? 45.384 71.284 21.924 1.00 42.68 ? 260 CYS A N 1 ATOM 2094 C CA . CYS A 1 260 ? 43.929 71.330 21.837 1.00 39.16 ? 260 CYS A CA 1 ATOM 2095 C C . CYS A 1 260 ? 43.510 71.605 20.414 1.00 36.33 ? 260 CYS A C 1 ATOM 2096 O O . CYS A 1 260 ? 44.047 72.497 19.771 1.00 36.68 ? 260 CYS A O 1 ATOM 2097 C CB . CYS A 1 260 ? 43.340 72.428 22.723 1.00 48.77 ? 260 CYS A CB 1 ATOM 2098 S SG . CYS A 1 260 ? 41.517 72.327 22.762 1.00 52.78 ? 260 CYS A SG 1 ATOM 2099 N N . HIS A 1 261 ? 42.545 70.847 19.916 1.00 40.45 ? 261 HIS A N 1 ATOM 2100 C CA . HIS A 1 261 ? 42.090 71.062 18.555 1.00 37.44 ? 261 HIS A CA 1 ATOM 2101 C C . HIS A 1 261 ? 40.618 71.463 18.522 1.00 46.38 ? 261 HIS A C 1 ATOM 2102 O O . HIS A 1 261 ? 39.764 70.775 19.069 1.00 37.80 ? 261 HIS A O 1 ATOM 2103 C CB . HIS A 1 261 ? 42.328 69.806 17.709 1.00 35.61 ? 261 HIS A CB 1 ATOM 2104 C CG . HIS A 1 261 ? 43.738 69.292 17.768 1.00 48.31 ? 261 HIS A CG 1 ATOM 2105 N ND1 . HIS A 1 261 ? 44.356 68.683 16.695 1.00 49.87 ? 261 HIS A ND1 1 ATOM 2106 C CD2 . HIS A 1 261 ? 44.637 69.264 18.783 1.00 52.48 ? 261 HIS A CD2 1 ATOM 2107 C CE1 . HIS A 1 261 ? 45.572 68.303 17.047 1.00 54.82 ? 261 HIS A CE1 1 ATOM 2108 N NE2 . HIS A 1 261 ? 45.766 68.644 18.309 1.00 55.23 ? 261 HIS A NE2 1 ATOM 2109 N N . VAL A 1 262 ? 40.333 72.590 17.880 1.00 36.34 ? 262 VAL A N 1 ATOM 2110 C CA . VAL A 1 262 ? 38.972 73.101 17.777 1.00 28.02 ? 262 VAL A CA 1 ATOM 2111 C C . VAL A 1 262 ? 38.478 73.152 16.327 1.00 34.80 ? 262 VAL A C 1 ATOM 2112 O O . VAL A 1 262 ? 39.166 73.663 15.456 1.00 35.93 ? 262 VAL A O 1 ATOM 2113 C CB . VAL A 1 262 ? 38.887 74.523 18.394 1.00 7.70 ? 262 VAL A CB 1 ATOM 2114 C CG1 . VAL A 1 262 ? 37.530 75.103 18.181 1.00 8.79 ? 262 VAL A CG1 1 ATOM 2115 C CG2 . VAL A 1 262 ? 39.185 74.464 19.866 1.00 6.26 ? 262 VAL A CG2 1 ATOM 2116 N N . GLN A 1 263 ? 37.290 72.614 16.071 1.00 56.79 ? 263 GLN A N 1 ATOM 2117 C CA . GLN A 1 263 ? 36.710 72.638 14.724 1.00 54.01 ? 263 GLN A CA 1 ATOM 2118 C C . GLN A 1 263 ? 35.385 73.396 14.776 1.00 61.66 ? 263 GLN A C 1 ATOM 2119 O O . GLN A 1 263 ? 34.740 73.445 15.819 1.00 60.45 ? 263 GLN A O 1 ATOM 2120 C CB . GLN A 1 263 ? 36.477 71.216 14.205 1.00 72.12 ? 263 GLN A CB 1 ATOM 2121 C CG . GLN A 1 263 ? 35.581 71.140 12.976 1.00 82.26 ? 263 GLN A CG 1 ATOM 2122 C CD . GLN A 1 263 ? 36.189 71.797 11.751 1.00 99.94 ? 263 GLN A CD 1 ATOM 2123 O OE1 . GLN A 1 263 ? 36.691 72.918 11.817 1.00 100.99 ? 263 GLN A OE1 1 ATOM 2124 N NE2 . GLN A 1 263 ? 36.132 71.104 10.617 1.00 106.02 ? 263 GLN A NE2 1 ATOM 2125 N N . HIS A 1 264 ? 34.978 73.986 13.655 1.00 38.22 ? 264 HIS A N 1 ATOM 2126 C CA . HIS A 1 264 ? 33.735 74.751 13.622 1.00 38.86 ? 264 HIS A CA 1 ATOM 2127 C C . HIS A 1 264 ? 33.313 75.090 12.204 1.00 43.00 ? 264 HIS A C 1 ATOM 2128 O O . HIS A 1 264 ? 34.110 75.012 11.284 1.00 44.17 ? 264 HIS A O 1 ATOM 2129 C CB . HIS A 1 264 ? 33.909 76.046 14.407 1.00 24.02 ? 264 HIS A CB 1 ATOM 2130 C CG . HIS A 1 264 ? 32.620 76.673 14.821 1.00 31.18 ? 264 HIS A CG 1 ATOM 2131 N ND1 . HIS A 1 264 ? 32.241 77.930 14.412 1.00 24.02 ? 264 HIS A ND1 1 ATOM 2132 C CD2 . HIS A 1 264 ? 31.618 76.212 15.605 1.00 24.02 ? 264 HIS A CD2 1 ATOM 2133 C CE1 . HIS A 1 264 ? 31.058 78.218 14.924 1.00 32.22 ? 264 HIS A CE1 1 ATOM 2134 N NE2 . HIS A 1 264 ? 30.658 77.191 15.652 1.00 25.25 ? 264 HIS A NE2 1 ATOM 2135 N N . SER A 1 265 ? 32.060 75.477 12.025 1.00 32.04 ? 265 SER A N 1 ATOM 2136 C CA . SER A 1 265 ? 31.584 75.818 10.698 1.00 33.94 ? 265 SER A CA 1 ATOM 2137 C C . SER A 1 265 ? 32.084 77.207 10.298 1.00 34.03 ? 265 SER A C 1 ATOM 2138 O O . SER A 1 265 ? 32.140 77.554 9.116 1.00 38.86 ? 265 SER A O 1 ATOM 2139 C CB . SER A 1 265 ? 30.059 75.785 10.674 1.00 30.82 ? 265 SER A CB 1 ATOM 2140 O OG . SER A 1 265 ? 29.525 76.714 11.596 1.00 31.26 ? 265 SER A OG 1 ATOM 2141 N N . SER A 1 266 ? 32.462 77.995 11.296 1.00 30.75 ? 266 SER A N 1 ATOM 2142 C CA . SER A 1 266 ? 32.929 79.350 11.070 1.00 29.00 ? 266 SER A CA 1 ATOM 2143 C C . SER A 1 266 ? 34.371 79.354 10.635 1.00 34.58 ? 266 SER A C 1 ATOM 2144 O O . SER A 1 266 ? 34.820 80.302 9.991 1.00 34.61 ? 266 SER A O 1 ATOM 2145 C CB . SER A 1 266 ? 32.824 80.154 12.349 1.00 33.78 ? 266 SER A CB 1 ATOM 2146 O OG . SER A 1 266 ? 33.794 79.692 13.272 1.00 33.87 ? 266 SER A OG 1 ATOM 2147 N N . LEU A 1 267 ? 35.100 78.302 10.997 1.00 22.47 ? 267 LEU A N 1 ATOM 2148 C CA . LEU A 1 267 ? 36.513 78.198 10.653 1.00 23.67 ? 267 LEU A CA 1 ATOM 2149 C C . LEU A 1 267 ? 36.778 77.557 9.300 1.00 32.83 ? 267 LEU A C 1 ATOM 2150 O O . LEU A 1 267 ? 36.114 76.594 8.929 1.00 32.03 ? 267 LEU A O 1 ATOM 2151 C CB . LEU A 1 267 ? 37.243 77.411 11.732 1.00 20.86 ? 267 LEU A CB 1 ATOM 2152 C CG . LEU A 1 267 ? 37.177 78.015 13.133 1.00 24.44 ? 267 LEU A CG 1 ATOM 2153 C CD1 . LEU A 1 267 ? 38.111 77.225 14.034 1.00 22.14 ? 267 LEU A CD1 1 ATOM 2154 C CD2 . LEU A 1 267 ? 37.579 79.494 13.118 1.00 19.13 ? 267 LEU A CD2 1 ATOM 2155 N N . ALA A 1 268 ? 37.756 78.090 8.569 1.00 22.79 ? 268 ALA A N 1 ATOM 2156 C CA . ALA A 1 268 ? 38.110 77.549 7.253 1.00 27.34 ? 268 ALA A CA 1 ATOM 2157 C C . ALA A 1 268 ? 38.832 76.208 7.400 1.00 26.34 ? 268 ALA A C 1 ATOM 2158 O O . ALA A 1 268 ? 38.717 75.322 6.557 1.00 23.71 ? 268 ALA A O 1 ATOM 2159 C CB . ALA A 1 268 ? 38.983 78.532 6.507 1.00 66.10 ? 268 ALA A CB 1 ATOM 2160 N N . GLN A 1 269 ? 39.585 76.082 8.483 1.00 35.04 ? 269 GLN A N 1 ATOM 2161 C CA . GLN A 1 269 ? 40.313 74.863 8.798 1.00 32.95 ? 269 GLN A CA 1 ATOM 2162 C C . GLN A 1 269 ? 40.433 74.805 10.310 1.00 29.88 ? 269 GLN A C 1 ATOM 2163 O O . GLN A 1 269 ? 40.368 75.831 10.981 1.00 26.89 ? 269 GLN A O 1 ATOM 2164 C CB . GLN A 1 269 ? 41.707 74.858 8.164 1.00 54.00 ? 269 GLN A CB 1 ATOM 2165 C CG . GLN A 1 269 ? 42.091 76.122 7.419 1.00 71.63 ? 269 GLN A CG 1 ATOM 2166 C CD . GLN A 1 269 ? 42.248 77.306 8.337 1.00 66.18 ? 269 GLN A CD 1 ATOM 2167 O OE1 . GLN A 1 269 ? 41.280 77.788 8.914 1.00 63.58 ? 269 GLN A OE1 1 ATOM 2168 N NE2 . GLN A 1 269 ? 43.476 77.778 8.486 1.00 75.48 ? 269 GLN A NE2 1 ATOM 2169 N N . PRO A 1 270 ? 40.596 73.600 10.870 1.00 29.25 ? 270 PRO A N 1 ATOM 2170 C CA . PRO A 1 270 ? 40.718 73.443 12.322 1.00 32.37 ? 270 PRO A CA 1 ATOM 2171 C C . PRO A 1 270 ? 41.836 74.250 12.980 1.00 34.02 ? 270 PRO A C 1 ATOM 2172 O O . PRO A 1 270 ? 42.863 74.532 12.373 1.00 35.57 ? 270 PRO A O 1 ATOM 2173 C CB . PRO A 1 270 ? 40.896 71.933 12.494 1.00 58.75 ? 270 PRO A CB 1 ATOM 2174 C CG . PRO A 1 270 ? 41.473 71.489 11.175 1.00 58.54 ? 270 PRO A CG 1 ATOM 2175 C CD . PRO A 1 270 ? 40.679 72.296 10.191 1.00 61.28 ? 270 PRO A CD 1 ATOM 2176 N N . LEU A 1 271 ? 41.609 74.630 14.229 1.00 26.72 ? 271 LEU A N 1 ATOM 2177 C CA . LEU A 1 271 ? 42.573 75.395 15.000 1.00 23.80 ? 271 LEU A CA 1 ATOM 2178 C C . LEU A 1 271 ? 43.332 74.445 15.905 1.00 27.68 ? 271 LEU A C 1 ATOM 2179 O O . LEU A 1 271 ? 42.861 73.352 16.209 1.00 29.95 ? 271 LEU A O 1 ATOM 2180 C CB . LEU A 1 271 ? 41.856 76.434 15.859 1.00 22.96 ? 271 LEU A CB 1 ATOM 2181 C CG . LEU A 1 271 ? 41.747 77.880 15.384 1.00 37.33 ? 271 LEU A CG 1 ATOM 2182 C CD1 . LEU A 1 271 ? 41.466 77.955 13.896 1.00 49.65 ? 271 LEU A CD1 1 ATOM 2183 C CD2 . LEU A 1 271 ? 40.648 78.551 16.175 1.00 34.19 ? 271 LEU A CD2 1 ATOM 2184 N N . VAL A 1 272 ? 44.516 74.858 16.330 1.00 23.13 ? 272 VAL A N 1 ATOM 2185 C CA . VAL A 1 272 ? 45.314 74.038 17.220 1.00 21.97 ? 272 VAL A CA 1 ATOM 2186 C C . VAL A 1 272 ? 45.920 74.938 18.277 1.00 23.77 ? 272 VAL A C 1 ATOM 2187 O O . VAL A 1 272 ? 46.378 76.039 17.981 1.00 27.06 ? 272 VAL A O 1 ATOM 2188 C CB . VAL A 1 272 ? 46.447 73.312 16.463 1.00 50.31 ? 272 VAL A CB 1 ATOM 2189 C CG1 . VAL A 1 272 ? 47.315 72.543 17.445 1.00 50.11 ? 272 VAL A CG1 1 ATOM 2190 C CG2 . VAL A 1 272 ? 45.861 72.362 15.437 1.00 44.68 ? 272 VAL A CG2 1 ATOM 2191 N N . VAL A 1 273 ? 45.913 74.473 19.516 1.00 33.59 ? 273 VAL A N 1 ATOM 2192 C CA . VAL A 1 273 ? 46.479 75.245 20.609 1.00 40.24 ? 273 VAL A CA 1 ATOM 2193 C C . VAL A 1 273 ? 47.247 74.336 21.567 1.00 49.72 ? 273 VAL A C 1 ATOM 2194 O O . VAL A 1 273 ? 46.655 73.587 22.342 1.00 53.58 ? 273 VAL A O 1 ATOM 2195 C CB . VAL A 1 273 ? 45.381 75.991 21.366 1.00 16.48 ? 273 VAL A CB 1 ATOM 2196 C CG1 . VAL A 1 273 ? 45.986 76.806 22.476 1.00 16.60 ? 273 VAL A CG1 1 ATOM 2197 C CG2 . VAL A 1 273 ? 44.631 76.882 20.418 1.00 15.65 ? 273 VAL A CG2 1 ATOM 2198 N N . PRO A 1 274 ? 48.585 74.388 21.516 1.00 83.38 ? 274 PRO A N 1 ATOM 2199 C CA . PRO A 1 274 ? 49.425 73.560 22.382 1.00 84.41 ? 274 PRO A CA 1 ATOM 2200 C C . PRO A 1 274 ? 49.574 74.157 23.773 1.00 84.47 ? 274 PRO A C 1 ATOM 2201 O O . PRO A 1 274 ? 49.395 75.360 23.961 1.00 81.59 ? 274 PRO A O 1 ATOM 2202 C CB . PRO A 1 274 ? 50.743 73.525 21.626 1.00 73.06 ? 274 PRO A CB 1 ATOM 2203 C CG . PRO A 1 274 ? 50.819 74.917 21.091 1.00 71.67 ? 274 PRO A CG 1 ATOM 2204 C CD . PRO A 1 274 ? 49.415 75.159 20.572 1.00 68.82 ? 274 PRO A CD 1 ATOM 2205 N N . TRP A 1 275 ? 49.900 73.311 24.744 1.00 80.60 ? 275 TRP A N 1 ATOM 2206 C CA . TRP A 1 275 ? 50.085 73.771 26.113 1.00 87.74 ? 275 TRP A CA 1 ATOM 2207 C C . TRP A 1 275 ? 51.570 73.803 26.462 1.00 94.38 ? 275 TRP A C 1 ATOM 2208 O O . TRP A 1 275 ? 52.209 72.759 26.625 1.00 92.20 ? 275 TRP A O 1 ATOM 2209 C CB . TRP A 1 275 ? 49.337 72.866 27.099 1.00 52.38 ? 275 TRP A CB 1 ATOM 2210 C CG . TRP A 1 275 ? 49.529 73.282 28.521 1.00 44.64 ? 275 TRP A CG 1 ATOM 2211 C CD1 . TRP A 1 275 ? 49.108 74.445 29.099 1.00 45.55 ? 275 TRP A CD1 1 ATOM 2212 C CD2 . TRP A 1 275 ? 50.276 72.584 29.520 1.00 42.61 ? 275 TRP A CD2 1 ATOM 2213 N NE1 . TRP A 1 275 ? 49.555 74.519 30.396 1.00 49.65 ? 275 TRP A NE1 1 ATOM 2214 C CE2 . TRP A 1 275 ? 50.276 73.389 30.681 1.00 45.92 ? 275 TRP A CE2 1 ATOM 2215 C CE3 . TRP A 1 275 ? 50.951 71.355 29.546 1.00 45.00 ? 275 TRP A CE3 1 ATOM 2216 C CZ2 . TRP A 1 275 ? 50.927 73.007 31.859 1.00 47.98 ? 275 TRP A CZ2 1 ATOM 2217 C CZ3 . TRP A 1 275 ? 51.601 70.971 30.721 1.00 53.71 ? 275 TRP A CZ3 1 ATOM 2218 C CH2 . TRP A 1 275 ? 51.583 71.798 31.862 1.00 54.09 ? 275 TRP A CH2 1 ATOM 2219 N N . GLU A 1 276 ? 52.109 75.014 26.567 1.00 95.44 ? 276 GLU A N 1 ATOM 2220 C CA . GLU A 1 276 ? 53.516 75.220 26.897 1.00 103.38 ? 276 GLU A CA 1 ATOM 2221 C C . GLU A 1 276 ? 53.733 75.138 28.409 1.00 106.98 ? 276 GLU A C 1 ATOM 2222 O O . GLU A 1 276 ? 53.388 76.064 29.149 1.00 106.35 ? 276 GLU A O 1 ATOM 2223 C CB . GLU A 1 276 ? 53.985 76.589 26.384 1.00 136.86 ? 276 GLU A CB 1 ATOM 2224 C CG . GLU A 1 276 ? 53.984 76.740 24.865 1.00 144.59 ? 276 GLU A CG 1 ATOM 2225 C CD . GLU A 1 276 ? 55.072 75.923 24.188 1.00 149.16 ? 276 GLU A CD 1 ATOM 2226 O OE1 . GLU A 1 276 ? 56.265 76.188 24.448 1.00 152.59 ? 276 GLU A OE1 1 ATOM 2227 O OE2 . GLU A 1 276 ? 54.736 75.017 23.396 1.00 149.34 ? 276 GLU A OE2 1 ATOM 2228 N N . ALA A 1 277 ? 54.309 74.027 28.859 1.00 121.14 ? 277 ALA A N 1 ATOM 2229 C CA . ALA A 1 277 ? 54.575 73.820 30.277 1.00 124.10 ? 277 ALA A CA 1 ATOM 2230 C C . ALA A 1 277 ? 55.503 74.904 30.830 1.00 127.23 ? 277 ALA A C 1 ATOM 2231 O O . ALA A 1 277 ? 55.916 75.786 30.047 1.00 127.63 ? 277 ALA A O 1 ATOM 2232 C CB . ALA A 1 277 ? 55.189 72.435 30.495 1.00 104.66 ? 277 ALA A CB 1 HETATM 2233 C C1 . NAG B 2 . ? 10.090 83.821 -0.002 1.00 73.63 ? 310 NAG A C1 1 HETATM 2234 C C2 . NAG B 2 . ? 8.881 84.701 0.406 1.00 74.24 ? 310 NAG A C2 1 HETATM 2235 C C3 . NAG B 2 . ? 8.638 85.846 -0.604 1.00 77.97 ? 310 NAG A C3 1 HETATM 2236 C C4 . NAG B 2 . ? 9.939 86.576 -0.941 1.00 81.31 ? 310 NAG A C4 1 HETATM 2237 C C5 . NAG B 2 . ? 10.984 85.550 -1.388 1.00 83.25 ? 310 NAG A C5 1 HETATM 2238 C C6 . NAG B 2 . ? 12.323 86.146 -1.777 1.00 85.90 ? 310 NAG A C6 1 HETATM 2239 C C7 . NAG B 2 . ? 6.810 83.773 -0.483 1.00 85.09 ? 310 NAG A C7 1 HETATM 2240 C C8 . NAG B 2 . ? 7.176 82.878 -1.657 1.00 79.64 ? 310 NAG A C8 1 HETATM 2241 N N2 . NAG B 2 . ? 7.689 83.871 0.516 1.00 73.99 ? 310 NAG A N2 1 HETATM 2242 O O3 . NAG B 2 . ? 7.703 86.776 -0.073 1.00 74.06 ? 310 NAG A O3 1 HETATM 2243 O O4 . NAG B 2 . ? 9.701 87.520 -1.976 1.00 85.85 ? 310 NAG A O4 1 HETATM 2244 O O5 . NAG B 2 . ? 11.233 84.625 -0.314 1.00 80.04 ? 310 NAG A O5 1 HETATM 2245 O O6 . NAG B 2 . ? 13.311 85.132 -1.911 1.00 82.35 ? 310 NAG A O6 1 HETATM 2246 O O7 . NAG B 2 . ? 5.723 84.355 -0.476 1.00 89.97 ? 310 NAG A O7 1 HETATM 2247 C C1 . NAG C 2 . ? 28.308 86.234 27.134 1.00 21.22 ? 320 NAG A C1 1 HETATM 2248 C C2 . NAG C 2 . ? 29.506 87.121 26.777 1.00 29.60 ? 320 NAG A C2 1 HETATM 2249 C C3 . NAG C 2 . ? 30.733 86.580 27.524 1.00 32.64 ? 320 NAG A C3 1 HETATM 2250 C C4 . NAG C 2 . ? 30.452 86.460 29.031 1.00 31.36 ? 320 NAG A C4 1 HETATM 2251 C C5 . NAG C 2 . ? 29.136 85.721 29.306 1.00 29.43 ? 320 NAG A C5 1 HETATM 2252 C C6 . NAG C 2 . ? 28.716 85.837 30.768 1.00 32.96 ? 320 NAG A C6 1 HETATM 2253 C C7 . NAG C 2 . ? 30.237 88.180 24.734 1.00 28.72 ? 320 NAG A C7 1 HETATM 2254 C C8 . NAG C 2 . ? 31.295 87.966 23.663 1.00 26.58 ? 320 NAG A C8 1 HETATM 2255 N N2 . NAG C 2 . ? 29.744 87.105 25.346 1.00 25.33 ? 320 NAG A N2 1 HETATM 2256 O O3 . NAG C 2 . ? 31.848 87.441 27.320 1.00 33.87 ? 320 NAG A O3 1 HETATM 2257 O O4 . NAG C 2 . ? 31.532 85.758 29.674 1.00 37.09 ? 320 NAG A O4 1 HETATM 2258 O O5 . NAG C 2 . ? 28.072 86.292 28.537 1.00 26.60 ? 320 NAG A O5 1 HETATM 2259 O O6 . NAG C 2 . ? 27.810 86.917 30.976 1.00 29.78 ? 320 NAG A O6 1 HETATM 2260 O O7 . NAG C 2 . ? 29.871 89.322 25.001 1.00 25.28 ? 320 NAG A O7 1 HETATM 2261 C C1 . NAG D 2 . ? 32.065 86.373 30.791 1.00 65.00 ? 321 NAG A C1 1 HETATM 2262 C C2 . NAG D 2 . ? 32.383 85.314 31.849 1.00 71.17 ? 321 NAG A C2 1 HETATM 2263 C C3 . NAG D 2 . ? 33.113 85.956 33.037 1.00 81.31 ? 321 NAG A C3 1 HETATM 2264 C C4 . NAG D 2 . ? 34.334 86.743 32.548 1.00 85.20 ? 321 NAG A C4 1 HETATM 2265 C C5 . NAG D 2 . ? 33.899 87.751 31.475 1.00 86.63 ? 321 NAG A C5 1 HETATM 2266 C C6 . NAG D 2 . ? 35.060 88.532 30.882 1.00 85.56 ? 321 NAG A C6 1 HETATM 2267 C C7 . NAG D 2 . ? 30.948 83.397 32.165 1.00 77.95 ? 321 NAG A C7 1 HETATM 2268 C C8 . NAG D 2 . ? 30.413 82.665 33.382 1.00 84.06 ? 321 NAG A C8 1 HETATM 2269 N N2 . NAG D 2 . ? 31.142 84.706 32.293 1.00 69.28 ? 321 NAG A N2 1 HETATM 2270 O O3 . NAG D 2 . ? 33.531 84.948 33.946 1.00 77.00 ? 321 NAG A O3 1 HETATM 2271 O O4 . NAG D 2 . ? 34.942 87.420 33.641 1.00 93.77 ? 321 NAG A O4 1 HETATM 2272 O O5 . NAG D 2 . ? 33.256 87.059 30.385 1.00 78.36 ? 321 NAG A O5 1 HETATM 2273 O O6 . NAG D 2 . ? 35.385 88.072 29.577 1.00 85.61 ? 321 NAG A O6 1 HETATM 2274 O O7 . NAG D 2 . ? 31.187 82.775 31.128 1.00 81.88 ? 321 NAG A O7 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLN 1 1 ? ? ? A . n A 1 2 GLU 2 2 ? ? ? A . n A 1 3 ASN 3 3 ? ? ? A . n A 1 4 GLN 4 4 ? ? ? A . n A 1 5 ASP 5 5 5 ASP ASP A . n A 1 6 GLY 6 6 6 GLY GLY A . n A 1 7 ARG 7 7 7 ARG ARG A . n A 1 8 TYR 8 8 8 TYR TYR A . n A 1 9 SER 9 9 9 SER SER A . n A 1 10 LEU 10 10 10 LEU LEU A . n A 1 11 THR 11 11 11 THR THR A . n A 1 12 TYR 12 12 12 TYR TYR A . n A 1 13 ILE 13 13 13 ILE ILE A . n A 1 14 TYR 14 14 14 TYR TYR A . n A 1 15 THR 15 15 15 THR THR A . n A 1 16 GLY 16 16 16 GLY GLY A . n A 1 17 LEU 17 17 17 LEU LEU A . n A 1 18 SER 18 18 18 SER SER A . n A 1 19 LYS 19 19 19 LYS LYS A . n A 1 20 HIS 20 20 20 HIS HIS A . n A 1 21 VAL 21 21 21 VAL VAL A . n A 1 22 GLU 22 22 22 GLU GLU A . n A 1 23 ASP 23 23 23 ASP ASP A . n A 1 24 VAL 24 24 24 VAL VAL A . n A 1 25 PRO 25 25 25 PRO PRO A . n A 1 26 ALA 26 26 26 ALA ALA A . n A 1 27 PHE 27 27 27 PHE PHE A . n A 1 28 GLN 28 28 28 GLN GLN A . n A 1 29 ALA 29 29 29 ALA ALA A . n A 1 30 LEU 30 30 30 LEU LEU A . n A 1 31 GLY 31 31 31 GLY GLY A . n A 1 32 SER 32 32 32 SER SER A . n A 1 33 LEU 33 33 33 LEU LEU A . n A 1 34 ASN 34 34 34 ASN ASN A . n A 1 35 ASP 35 35 35 ASP ASP A . n A 1 36 LEU 36 36 36 LEU LEU A . n A 1 37 GLN 37 37 37 GLN GLN A . n A 1 38 PHE 38 38 38 PHE PHE A . n A 1 39 PHE 39 39 39 PHE PHE A . n A 1 40 ARG 40 40 40 ARG ARG A . n A 1 41 TYR 41 41 41 TYR TYR A . n A 1 42 ASN 42 42 42 ASN ASN A . n A 1 43 SER 43 43 43 SER SER A . n A 1 44 LYS 44 44 44 LYS LYS A . n A 1 45 ASP 45 45 45 ASP ASP A . n A 1 46 ARG 46 46 46 ARG ARG A . n A 1 47 LYS 47 47 47 LYS LYS A . n A 1 48 SER 48 48 48 SER SER A . n A 1 49 GLN 49 49 49 GLN GLN A . n A 1 50 PRO 50 50 50 PRO PRO A . n A 1 51 MET 51 51 51 MET MET A . n A 1 52 GLY 52 52 52 GLY GLY A . n A 1 53 LEU 53 53 53 LEU LEU A . n A 1 54 TRP 54 54 54 TRP TRP A . n A 1 55 ARG 55 55 55 ARG ARG A . n A 1 56 GLN 56 56 56 GLN GLN A . n A 1 57 VAL 57 57 57 VAL VAL A . n A 1 58 GLU 58 58 58 GLU GLU A . n A 1 59 GLY 59 59 59 GLY GLY A . n A 1 60 MET 60 60 60 MET MET A . n A 1 61 GLU 61 61 61 GLU GLU A . n A 1 62 ASP 62 62 62 ASP ASP A . n A 1 63 TRP 63 63 63 TRP TRP A . n A 1 64 LYS 64 64 64 LYS LYS A . n A 1 65 GLN 65 65 65 GLN GLN A . n A 1 66 ASP 66 66 66 ASP ASP A . n A 1 67 SER 67 67 67 SER SER A . n A 1 68 GLN 68 68 68 GLN GLN A . n A 1 69 LEU 69 69 69 LEU LEU A . n A 1 70 GLN 70 70 70 GLN GLN A . n A 1 71 LYS 71 71 71 LYS LYS A . n A 1 72 ALA 72 72 72 ALA ALA A . n A 1 73 ARG 73 73 73 ARG ARG A . n A 1 74 GLU 74 74 74 GLU GLU A . n A 1 75 ASP 75 75 75 ASP ASP A . n A 1 76 ILE 76 76 76 ILE ILE A . n A 1 77 PHE 77 77 77 PHE PHE A . n A 1 78 MET 78 78 78 MET MET A . n A 1 79 GLU 79 79 79 GLU GLU A . n A 1 80 THR 80 80 80 THR THR A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 LYS 82 82 82 LYS LYS A . n A 1 83 ASP 83 83 83 ASP ASP A . n A 1 84 ILE 84 84 84 ILE ILE A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 GLU 86 86 86 GLU GLU A . n A 1 87 TYR 87 87 87 TYR TYR A . n A 1 88 TYR 88 88 88 TYR TYR A . n A 1 89 LYS 89 89 89 LYS LYS A . n A 1 90 ASP 90 90 90 ASP ASP A . n A 1 91 SER 91 91 91 SER SER A . n A 1 92 THR 92 92 92 THR THR A . n A 1 93 GLY 93 93 93 GLY GLY A . n A 1 94 SER 94 94 94 SER SER A . n A 1 95 HIS 95 95 95 HIS HIS A . n A 1 96 VAL 96 96 96 VAL VAL A . n A 1 97 LEU 97 97 97 LEU LEU A . n A 1 98 GLN 98 98 98 GLN GLN A . n A 1 99 GLY 99 99 99 GLY GLY A . n A 1 100 ARG 100 100 100 ARG ARG A . n A 1 101 PHE 101 101 101 PHE PHE A . n A 1 102 GLY 102 102 102 GLY GLY A . n A 1 103 CYS 103 103 103 CYS CYS A . n A 1 104 GLU 104 104 104 GLU GLU A . n A 1 105 ILE 105 105 105 ILE ILE A . n A 1 106 GLU 106 106 106 GLU GLU A . n A 1 107 ASN 107 107 107 ASN ASN A . n A 1 108 ASN 108 108 108 ASN ASN A . n A 1 109 ARG 109 109 109 ARG ARG A . n A 1 110 SER 110 110 110 SER SER A . n A 1 111 SER 111 111 111 SER SER A . n A 1 112 GLY 112 112 112 GLY GLY A . n A 1 113 ALA 113 113 113 ALA ALA A . n A 1 114 PHE 114 114 114 PHE PHE A . n A 1 115 TRP 115 115 115 TRP TRP A . n A 1 116 LYS 116 116 116 LYS LYS A . n A 1 117 TYR 117 117 117 TYR TYR A . n A 1 118 TYR 118 118 118 TYR TYR A . n A 1 119 TYR 119 119 119 TYR TYR A . n A 1 120 ASP 120 120 120 ASP ASP A . n A 1 121 GLY 121 121 121 GLY GLY A . n A 1 122 LYS 122 122 122 LYS LYS A . n A 1 123 ASP 123 123 123 ASP ASP A . n A 1 124 TYR 124 124 124 TYR TYR A . n A 1 125 ILE 125 125 125 ILE ILE A . n A 1 126 GLU 126 126 126 GLU GLU A . n A 1 127 PHE 127 127 127 PHE PHE A . n A 1 128 ASN 128 128 128 ASN ASN A . n A 1 129 LYS 129 129 129 LYS LYS A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 PRO 132 132 132 PRO PRO A . n A 1 133 ALA 133 133 133 ALA ALA A . n A 1 134 TRP 134 134 134 TRP TRP A . n A 1 135 VAL 135 135 135 VAL VAL A . n A 1 136 PRO 136 136 136 PRO PRO A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 ASP 138 138 138 ASP ASP A . n A 1 139 PRO 139 139 139 PRO PRO A . n A 1 140 ALA 140 140 140 ALA ALA A . n A 1 141 ALA 141 141 141 ALA ALA A . n A 1 142 GLN 142 142 142 GLN GLN A . n A 1 143 ILE 143 143 143 ILE ILE A . n A 1 144 THR 144 144 144 THR THR A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 GLN 146 146 146 GLN GLN A . n A 1 147 LYS 147 147 147 LYS LYS A . n A 1 148 TRP 148 148 148 TRP TRP A . n A 1 149 GLU 149 149 149 GLU GLU A . n A 1 150 ALA 150 150 150 ALA ALA A . n A 1 151 GLU 151 151 151 GLU GLU A . n A 1 152 PRO 152 152 152 PRO PRO A . n A 1 153 VAL 153 153 153 VAL VAL A . n A 1 154 TYR 154 154 154 TYR TYR A . n A 1 155 VAL 155 155 155 VAL VAL A . n A 1 156 GLN 156 156 156 GLN GLN A . n A 1 157 ARG 157 157 157 ARG ARG A . n A 1 158 ALA 158 158 158 ALA ALA A . n A 1 159 LYS 159 159 159 LYS LYS A . n A 1 160 ALA 160 160 160 ALA ALA A . n A 1 161 TYR 161 161 161 TYR TYR A . n A 1 162 LEU 162 162 162 LEU LEU A . n A 1 163 GLU 163 163 163 GLU GLU A . n A 1 164 GLU 164 164 164 GLU GLU A . n A 1 165 GLU 165 165 165 GLU GLU A . n A 1 166 CYS 166 166 166 CYS CYS A . n A 1 167 PRO 167 167 167 PRO PRO A . n A 1 168 ALA 168 168 168 ALA ALA A . n A 1 169 THR 169 169 169 THR THR A . n A 1 170 LEU 170 170 170 LEU LEU A . n A 1 171 ARG 171 171 171 ARG ARG A . n A 1 172 LYS 172 172 172 LYS LYS A . n A 1 173 TYR 173 173 173 TYR TYR A . n A 1 174 LEU 174 174 174 LEU LEU A . n A 1 175 LYS 175 175 175 LYS LYS A . n A 1 176 TYR 176 176 176 TYR TYR A . n A 1 177 SER 177 177 177 SER SER A . n A 1 178 LYS 178 178 178 LYS LYS A . n A 1 179 ASN 179 179 179 ASN ASN A . n A 1 180 ILE 180 180 180 ILE ILE A . n A 1 181 LEU 181 181 181 LEU LEU A . n A 1 182 ASP 182 182 182 ASP ASP A . n A 1 183 ARG 183 183 183 ARG ARG A . n A 1 184 GLN 184 184 184 GLN GLN A . n A 1 185 ASP 185 185 185 ASP ASP A . n A 1 186 PRO 186 186 186 PRO PRO A . n A 1 187 PRO 187 187 187 PRO PRO A . n A 1 188 SER 188 188 188 SER SER A . n A 1 189 VAL 189 189 189 VAL VAL A . n A 1 190 VAL 190 190 190 VAL VAL A . n A 1 191 VAL 191 191 191 VAL VAL A . n A 1 192 THR 192 192 192 THR THR A . n A 1 193 SER 193 193 193 SER SER A . n A 1 194 HIS 194 194 194 HIS HIS A . n A 1 195 GLN 195 195 195 GLN GLN A . n A 1 196 ALA 196 196 196 ALA ALA A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 GLY 198 198 198 GLY GLY A . n A 1 199 GLU 199 199 199 GLU GLU A . n A 1 200 LYS 200 200 200 LYS LYS A . n A 1 201 LYS 201 201 201 LYS LYS A . n A 1 202 LYS 202 202 202 LYS LYS A . n A 1 203 LEU 203 203 203 LEU LEU A . n A 1 204 LYS 204 204 204 LYS LYS A . n A 1 205 CYS 205 205 205 CYS CYS A . n A 1 206 LEU 206 206 206 LEU LEU A . n A 1 207 ALA 207 207 207 ALA ALA A . n A 1 208 TYR 208 208 208 TYR TYR A . n A 1 209 ASP 209 209 209 ASP ASP A . n A 1 210 PHE 210 210 210 PHE PHE A . n A 1 211 TYR 211 211 211 TYR TYR A . n A 1 212 PRO 212 212 212 PRO PRO A . n A 1 213 GLY 213 213 213 GLY GLY A . n A 1 214 LYS 214 214 214 LYS LYS A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 ASP 216 216 216 ASP ASP A . n A 1 217 VAL 217 217 217 VAL VAL A . n A 1 218 HIS 218 218 218 HIS HIS A . n A 1 219 TRP 219 219 219 TRP TRP A . n A 1 220 THR 220 220 220 THR THR A . n A 1 221 ARG 221 221 221 ARG ARG A . n A 1 222 ALA 222 222 222 ALA ALA A . n A 1 223 GLY 223 223 223 GLY GLY A . n A 1 224 GLU 224 224 224 GLU GLU A . n A 1 225 VAL 225 225 225 VAL VAL A . n A 1 226 GLN 226 226 226 GLN GLN A . n A 1 227 GLU 227 227 227 GLU GLU A . n A 1 228 PRO 228 228 228 PRO PRO A . n A 1 229 GLU 229 229 229 GLU GLU A . n A 1 230 LEU 230 230 230 LEU LEU A . n A 1 231 ARG 231 231 231 ARG ARG A . n A 1 232 GLY 232 232 232 GLY GLY A . n A 1 233 ASP 233 233 233 ASP ASP A . n A 1 234 VAL 234 234 234 VAL VAL A . n A 1 235 LEU 235 235 235 LEU LEU A . n A 1 236 HIS 236 236 236 HIS HIS A . n A 1 237 ASN 237 237 237 ASN ASN A . n A 1 238 GLY 238 238 238 GLY GLY A . n A 1 239 ASN 239 239 239 ASN ASN A . n A 1 240 GLY 240 240 240 GLY GLY A . n A 1 241 THR 241 241 241 THR THR A . n A 1 242 TYR 242 242 242 TYR TYR A . n A 1 243 GLN 243 243 243 GLN GLN A . n A 1 244 SER 244 244 244 SER SER A . n A 1 245 TRP 245 245 245 TRP TRP A . n A 1 246 VAL 246 246 246 VAL VAL A . n A 1 247 VAL 247 247 247 VAL VAL A . n A 1 248 VAL 248 248 248 VAL VAL A . n A 1 249 ALA 249 249 249 ALA ALA A . n A 1 250 VAL 250 250 250 VAL VAL A . n A 1 251 PRO 251 251 251 PRO PRO A . n A 1 252 PRO 252 252 252 PRO PRO A . n A 1 253 GLN 253 253 253 GLN GLN A . n A 1 254 ASP 254 254 254 ASP ASP A . n A 1 255 THR 255 255 255 THR THR A . n A 1 256 ALA 256 256 256 ALA ALA A . n A 1 257 PRO 257 257 257 PRO PRO A . n A 1 258 TYR 258 258 258 TYR TYR A . n A 1 259 SER 259 259 259 SER SER A . n A 1 260 CYS 260 260 260 CYS CYS A . n A 1 261 HIS 261 261 261 HIS HIS A . n A 1 262 VAL 262 262 262 VAL VAL A . n A 1 263 GLN 263 263 263 GLN GLN A . n A 1 264 HIS 264 264 264 HIS HIS A . n A 1 265 SER 265 265 265 SER SER A . n A 1 266 SER 266 266 266 SER SER A . n A 1 267 LEU 267 267 267 LEU LEU A . n A 1 268 ALA 268 268 268 ALA ALA A . n A 1 269 GLN 269 269 269 GLN GLN A . n A 1 270 PRO 270 270 270 PRO PRO A . n A 1 271 LEU 271 271 271 LEU LEU A . n A 1 272 VAL 272 272 272 VAL VAL A . n A 1 273 VAL 273 273 273 VAL VAL A . n A 1 274 PRO 274 274 274 PRO PRO A . n A 1 275 TRP 275 275 275 TRP TRP A . n A 1 276 GLU 276 276 276 GLU GLU A . n A 1 277 ALA 277 277 277 ALA ALA A . n A 1 278 SER 278 278 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 310 310 NAG NAG A . C 2 NAG 1 320 320 NAG NAG A . D 2 NAG 2 321 321 NAG NAG A . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 108 A ASN 108 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 239 A ASN 239 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2004-12-21 2 'Structure model' 1 1 2008-04-30 3 'Structure model' 1 2 2011-07-13 4 'Structure model' 1 3 2017-10-11 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' 4 4 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 4 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # _phasing.method MR # loop_ _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id _software.pdbx_ordinal CNS 1.1 1998 package 'Axel T. Brunger' axel.brunger@yale.edu refinement http://cns.csb.yale.edu/v1.1/ Fortran_77 ? 1 DENZO . ? package 'Zbyszek Otwinowski' zbyszek@mix.swmed.edu 'data reduction' http://www.lnls.br/infra/linhasluz/denzo-hkl.htm ? ? 2 SCALEPACK . ? package 'Zbyszek Otwinowski' zbyszek@mix.swmed.edu 'data scaling' http://www.lnls.br/infra/linhasluz/denzo-hkl.htm ? ? 3 AMoRE . ? ? ? ? phasing ? ? ? 4 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 23 ? ? 81.44 8.35 2 1 ASN A 34 ? ? 53.46 -122.55 3 1 TRP A 115 ? ? -160.64 101.08 4 1 GLU A 164 ? ? -125.49 -57.92 5 1 ASN A 179 ? ? -55.67 7.97 6 1 ILE A 180 ? ? -123.46 -64.76 7 1 ARG A 183 ? ? -47.28 156.32 8 1 PRO A 197 ? ? -68.56 83.10 9 1 TYR A 211 ? ? -172.20 135.40 10 1 PRO A 212 ? ? -58.24 176.23 11 1 GLN A 253 ? ? -112.80 65.04 12 1 ALA A 256 ? ? -39.28 147.00 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLN 1 ? A GLN 1 2 1 Y 1 A GLU 2 ? A GLU 2 3 1 Y 1 A ASN 3 ? A ASN 3 4 1 Y 1 A GLN 4 ? A GLN 4 5 1 Y 1 A SER 278 ? A SER 278 # _pdbx_entity_nonpoly.entity_id 2 _pdbx_entity_nonpoly.name N-ACETYL-D-GLUCOSAMINE _pdbx_entity_nonpoly.comp_id NAG #