data_1QX1 # _entry.id 1QX1 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 1QX1 RCSB RCSB020171 WWPDB D_1000020171 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1QWN . unspecified PDB 1QWU . unspecified PDB 1PS3 . unspecified PDB 1HTY . unspecified PDB 1HWW . unspecified PDB 1HXK . unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 1QX1 _pdbx_database_status.recvd_initial_deposition_date 2003-09-04 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.SG_entry . _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Numao, S.' 1 'Kuntz, D.A.' 2 'Withers, S.G.' 3 'Rose, D.R.' 4 # _citation.id primary _citation.title ;Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates. ; _citation.journal_abbrev J.Biol.Chem. _citation.journal_volume 278 _citation.page_first 48074 _citation.page_last 48083 _citation.year 2003 _citation.journal_id_ASTM JBCHA3 _citation.country US _citation.journal_id_ISSN 0021-9258 _citation.journal_id_CSD 0071 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 12960159 _citation.pdbx_database_id_DOI 10.1074/jbc.M309249200 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Numao, S.' 1 primary 'Kuntz, D.A.' 2 primary 'Withers, S.G.' 3 primary 'Rose, D.R.' 4 # _cell.entry_id 1QX1 _cell.length_a 69.046 _cell.length_b 109.826 _cell.length_c 138.907 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? # _symmetry.entry_id 1QX1 _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Alpha-mannosidase II' 119700.633 1 3.2.1.114 D341N 'Family 38 catalytic domain (residues 94-1108)' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 4 non-polymer syn '2-DEOXY-2-FLUOROHEXOPYRANOSYL FLUORIDE' 184.138 1 ? ? ? ? 5 non-polymer syn '(4S)-2-METHYL-2,4-PENTANEDIOL' 118.174 1 ? ? ? ? 6 water nat water 18.015 1042 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDNFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_seq_one_letter_code_can ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDNFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 SER n 1 3 SER n 1 4 HIS n 1 5 HIS n 1 6 HIS n 1 7 HIS n 1 8 HIS n 1 9 HIS n 1 10 GLY n 1 11 GLU n 1 12 PHE n 1 13 ASP n 1 14 ASP n 1 15 PRO n 1 16 ILE n 1 17 ARG n 1 18 PRO n 1 19 PRO n 1 20 LEU n 1 21 LYS n 1 22 VAL n 1 23 ALA n 1 24 ARG n 1 25 SER n 1 26 PRO n 1 27 ARG n 1 28 PRO n 1 29 GLY n 1 30 GLN n 1 31 CYS n 1 32 GLN n 1 33 ASP n 1 34 VAL n 1 35 VAL n 1 36 GLN n 1 37 ASP n 1 38 VAL n 1 39 PRO n 1 40 ASN n 1 41 VAL n 1 42 ASP n 1 43 VAL n 1 44 GLN n 1 45 MET n 1 46 LEU n 1 47 GLU n 1 48 LEU n 1 49 TYR n 1 50 ASP n 1 51 ARG n 1 52 MET n 1 53 SER n 1 54 PHE n 1 55 LYS n 1 56 ASP n 1 57 ILE n 1 58 ASP n 1 59 GLY n 1 60 GLY n 1 61 VAL n 1 62 TRP n 1 63 LYS n 1 64 GLN n 1 65 GLY n 1 66 TRP n 1 67 ASN n 1 68 ILE n 1 69 LYS n 1 70 TYR n 1 71 ASP n 1 72 PRO n 1 73 LEU n 1 74 LYS n 1 75 TYR n 1 76 ASN n 1 77 ALA n 1 78 HIS n 1 79 HIS n 1 80 LYS n 1 81 LEU n 1 82 LYS n 1 83 VAL n 1 84 PHE n 1 85 VAL n 1 86 VAL n 1 87 PRO n 1 88 HIS n 1 89 SER n 1 90 HIS n 1 91 ASN n 1 92 ASP n 1 93 PRO n 1 94 GLY n 1 95 TRP n 1 96 ILE n 1 97 GLN n 1 98 THR n 1 99 PHE n 1 100 GLU n 1 101 GLU n 1 102 TYR n 1 103 TYR n 1 104 GLN n 1 105 HIS n 1 106 ASP n 1 107 THR n 1 108 LYS n 1 109 HIS n 1 110 ILE n 1 111 LEU n 1 112 SER n 1 113 ASN n 1 114 ALA n 1 115 LEU n 1 116 ARG n 1 117 HIS n 1 118 LEU n 1 119 HIS n 1 120 ASP n 1 121 ASN n 1 122 PRO n 1 123 GLU n 1 124 MET n 1 125 LYS n 1 126 PHE n 1 127 ILE n 1 128 TRP n 1 129 ALA n 1 130 GLU n 1 131 ILE n 1 132 SER n 1 133 TYR n 1 134 PHE n 1 135 ALA n 1 136 ARG n 1 137 PHE n 1 138 TYR n 1 139 HIS n 1 140 ASP n 1 141 LEU n 1 142 GLY n 1 143 GLU n 1 144 ASN n 1 145 LYS n 1 146 LYS n 1 147 LEU n 1 148 GLN n 1 149 MET n 1 150 LYS n 1 151 SER n 1 152 ILE n 1 153 VAL n 1 154 LYS n 1 155 ASN n 1 156 GLY n 1 157 GLN n 1 158 LEU n 1 159 GLU n 1 160 PHE n 1 161 VAL n 1 162 THR n 1 163 GLY n 1 164 GLY n 1 165 TRP n 1 166 VAL n 1 167 MET n 1 168 PRO n 1 169 ASP n 1 170 GLU n 1 171 ALA n 1 172 ASN n 1 173 SER n 1 174 HIS n 1 175 TRP n 1 176 ARG n 1 177 ASN n 1 178 VAL n 1 179 LEU n 1 180 LEU n 1 181 GLN n 1 182 LEU n 1 183 THR n 1 184 GLU n 1 185 GLY n 1 186 GLN n 1 187 THR n 1 188 TRP n 1 189 LEU n 1 190 LYS n 1 191 GLN n 1 192 PHE n 1 193 MET n 1 194 ASN n 1 195 VAL n 1 196 THR n 1 197 PRO n 1 198 THR n 1 199 ALA n 1 200 SER n 1 201 TRP n 1 202 ALA n 1 203 ILE n 1 204 ASP n 1 205 PRO n 1 206 PHE n 1 207 GLY n 1 208 HIS n 1 209 SER n 1 210 PRO n 1 211 THR n 1 212 MET n 1 213 PRO n 1 214 TYR n 1 215 ILE n 1 216 LEU n 1 217 GLN n 1 218 LYS n 1 219 SER n 1 220 GLY n 1 221 PHE n 1 222 LYS n 1 223 ASN n 1 224 MET n 1 225 LEU n 1 226 ILE n 1 227 GLN n 1 228 ARG n 1 229 THR n 1 230 HIS n 1 231 TYR n 1 232 SER n 1 233 VAL n 1 234 LYS n 1 235 LYS n 1 236 GLU n 1 237 LEU n 1 238 ALA n 1 239 GLN n 1 240 GLN n 1 241 ARG n 1 242 GLN n 1 243 LEU n 1 244 GLU n 1 245 PHE n 1 246 LEU n 1 247 TRP n 1 248 ARG n 1 249 GLN n 1 250 ILE n 1 251 TRP n 1 252 ASP n 1 253 ASN n 1 254 LYS n 1 255 GLY n 1 256 ASP n 1 257 THR n 1 258 ALA n 1 259 LEU n 1 260 PHE n 1 261 THR n 1 262 HIS n 1 263 MET n 1 264 MET n 1 265 PRO n 1 266 PHE n 1 267 TYR n 1 268 SER n 1 269 TYR n 1 270 ASP n 1 271 ILE n 1 272 PRO n 1 273 HIS n 1 274 THR n 1 275 CYS n 1 276 GLY n 1 277 PRO n 1 278 ASP n 1 279 PRO n 1 280 LYS n 1 281 VAL n 1 282 CYS n 1 283 CYS n 1 284 GLN n 1 285 PHE n 1 286 ASP n 1 287 PHE n 1 288 LYS n 1 289 ARG n 1 290 MET n 1 291 GLY n 1 292 SER n 1 293 PHE n 1 294 GLY n 1 295 LEU n 1 296 SER n 1 297 CYS n 1 298 PRO n 1 299 TRP n 1 300 LYS n 1 301 VAL n 1 302 PRO n 1 303 PRO n 1 304 ARG n 1 305 THR n 1 306 ILE n 1 307 SER n 1 308 ASP n 1 309 GLN n 1 310 ASN n 1 311 VAL n 1 312 ALA n 1 313 ALA n 1 314 ARG n 1 315 SER n 1 316 ASP n 1 317 LEU n 1 318 LEU n 1 319 VAL n 1 320 ASP n 1 321 GLN n 1 322 TRP n 1 323 LYS n 1 324 LYS n 1 325 LYS n 1 326 ALA n 1 327 GLU n 1 328 LEU n 1 329 TYR n 1 330 ARG n 1 331 THR n 1 332 ASN n 1 333 VAL n 1 334 LEU n 1 335 LEU n 1 336 ILE n 1 337 PRO n 1 338 LEU n 1 339 GLY n 1 340 ASP n 1 341 ASN n 1 342 PHE n 1 343 ARG n 1 344 PHE n 1 345 LYS n 1 346 GLN n 1 347 ASN n 1 348 THR n 1 349 GLU n 1 350 TRP n 1 351 ASP n 1 352 VAL n 1 353 GLN n 1 354 ARG n 1 355 VAL n 1 356 ASN n 1 357 TYR n 1 358 GLU n 1 359 ARG n 1 360 LEU n 1 361 PHE n 1 362 GLU n 1 363 HIS n 1 364 ILE n 1 365 ASN n 1 366 SER n 1 367 GLN n 1 368 ALA n 1 369 HIS n 1 370 PHE n 1 371 ASN n 1 372 VAL n 1 373 GLN n 1 374 ALA n 1 375 GLN n 1 376 PHE n 1 377 GLY n 1 378 THR n 1 379 LEU n 1 380 GLN n 1 381 GLU n 1 382 TYR n 1 383 PHE n 1 384 ASP n 1 385 ALA n 1 386 VAL n 1 387 HIS n 1 388 GLN n 1 389 ALA n 1 390 GLU n 1 391 ARG n 1 392 ALA n 1 393 GLY n 1 394 GLN n 1 395 ALA n 1 396 GLU n 1 397 PHE n 1 398 PRO n 1 399 THR n 1 400 LEU n 1 401 SER n 1 402 GLY n 1 403 ASP n 1 404 PHE n 1 405 PHE n 1 406 THR n 1 407 TYR n 1 408 ALA n 1 409 ASP n 1 410 ARG n 1 411 SER n 1 412 ASP n 1 413 ASN n 1 414 TYR n 1 415 TRP n 1 416 SER n 1 417 GLY n 1 418 TYR n 1 419 TYR n 1 420 THR n 1 421 SER n 1 422 ARG n 1 423 PRO n 1 424 TYR n 1 425 HIS n 1 426 LYS n 1 427 ARG n 1 428 MET n 1 429 ASP n 1 430 ARG n 1 431 VAL n 1 432 LEU n 1 433 MET n 1 434 HIS n 1 435 TYR n 1 436 VAL n 1 437 ARG n 1 438 ALA n 1 439 ALA n 1 440 GLU n 1 441 MET n 1 442 LEU n 1 443 SER n 1 444 ALA n 1 445 TRP n 1 446 HIS n 1 447 SER n 1 448 TRP n 1 449 ASP n 1 450 GLY n 1 451 MET n 1 452 ALA n 1 453 ARG n 1 454 ILE n 1 455 GLU n 1 456 GLU n 1 457 ARG n 1 458 LEU n 1 459 GLU n 1 460 GLN n 1 461 ALA n 1 462 ARG n 1 463 ARG n 1 464 GLU n 1 465 LEU n 1 466 SER n 1 467 LEU n 1 468 PHE n 1 469 GLN n 1 470 HIS n 1 471 HIS n 1 472 ASP n 1 473 GLY n 1 474 ILE n 1 475 THR n 1 476 GLY n 1 477 THR n 1 478 ALA n 1 479 LYS n 1 480 THR n 1 481 HIS n 1 482 VAL n 1 483 VAL n 1 484 VAL n 1 485 ASP n 1 486 TYR n 1 487 GLU n 1 488 GLN n 1 489 ARG n 1 490 MET n 1 491 GLN n 1 492 GLU n 1 493 ALA n 1 494 LEU n 1 495 LYS n 1 496 ALA n 1 497 CYS n 1 498 GLN n 1 499 MET n 1 500 VAL n 1 501 MET n 1 502 GLN n 1 503 GLN n 1 504 SER n 1 505 VAL n 1 506 TYR n 1 507 ARG n 1 508 LEU n 1 509 LEU n 1 510 THR n 1 511 LYS n 1 512 PRO n 1 513 SER n 1 514 ILE n 1 515 TYR n 1 516 SER n 1 517 PRO n 1 518 ASP n 1 519 PHE n 1 520 SER n 1 521 PHE n 1 522 SER n 1 523 TYR n 1 524 PHE n 1 525 THR n 1 526 LEU n 1 527 ASP n 1 528 ASP n 1 529 SER n 1 530 ARG n 1 531 TRP n 1 532 PRO n 1 533 GLY n 1 534 SER n 1 535 GLY n 1 536 VAL n 1 537 GLU n 1 538 ASP n 1 539 SER n 1 540 ARG n 1 541 THR n 1 542 THR n 1 543 ILE n 1 544 ILE n 1 545 LEU n 1 546 GLY n 1 547 GLU n 1 548 ASP n 1 549 ILE n 1 550 LEU n 1 551 PRO n 1 552 SER n 1 553 LYS n 1 554 HIS n 1 555 VAL n 1 556 VAL n 1 557 MET n 1 558 HIS n 1 559 ASN n 1 560 THR n 1 561 LEU n 1 562 PRO n 1 563 HIS n 1 564 TRP n 1 565 ARG n 1 566 GLU n 1 567 GLN n 1 568 LEU n 1 569 VAL n 1 570 ASP n 1 571 PHE n 1 572 TYR n 1 573 VAL n 1 574 SER n 1 575 SER n 1 576 PRO n 1 577 PHE n 1 578 VAL n 1 579 SER n 1 580 VAL n 1 581 THR n 1 582 ASP n 1 583 LEU n 1 584 ALA n 1 585 ASN n 1 586 ASN n 1 587 PRO n 1 588 VAL n 1 589 GLU n 1 590 ALA n 1 591 GLN n 1 592 VAL n 1 593 SER n 1 594 PRO n 1 595 VAL n 1 596 TRP n 1 597 SER n 1 598 TRP n 1 599 HIS n 1 600 HIS n 1 601 ASP n 1 602 THR n 1 603 LEU n 1 604 THR n 1 605 LYS n 1 606 THR n 1 607 ILE n 1 608 HIS n 1 609 PRO n 1 610 GLN n 1 611 GLY n 1 612 SER n 1 613 THR n 1 614 THR n 1 615 LYS n 1 616 TYR n 1 617 ARG n 1 618 ILE n 1 619 ILE n 1 620 PHE n 1 621 LYS n 1 622 ALA n 1 623 ARG n 1 624 VAL n 1 625 PRO n 1 626 PRO n 1 627 MET n 1 628 GLY n 1 629 LEU n 1 630 ALA n 1 631 THR n 1 632 TYR n 1 633 VAL n 1 634 LEU n 1 635 THR n 1 636 ILE n 1 637 SER n 1 638 ASP n 1 639 SER n 1 640 LYS n 1 641 PRO n 1 642 GLU n 1 643 HIS n 1 644 THR n 1 645 SER n 1 646 TYR n 1 647 ALA n 1 648 SER n 1 649 ASN n 1 650 LEU n 1 651 LEU n 1 652 LEU n 1 653 ARG n 1 654 LYS n 1 655 ASN n 1 656 PRO n 1 657 THR n 1 658 SER n 1 659 LEU n 1 660 PRO n 1 661 LEU n 1 662 GLY n 1 663 GLN n 1 664 TYR n 1 665 PRO n 1 666 GLU n 1 667 ASP n 1 668 VAL n 1 669 LYS n 1 670 PHE n 1 671 GLY n 1 672 ASP n 1 673 PRO n 1 674 ARG n 1 675 GLU n 1 676 ILE n 1 677 SER n 1 678 LEU n 1 679 ARG n 1 680 VAL n 1 681 GLY n 1 682 ASN n 1 683 GLY n 1 684 PRO n 1 685 THR n 1 686 LEU n 1 687 ALA n 1 688 PHE n 1 689 SER n 1 690 GLU n 1 691 GLN n 1 692 GLY n 1 693 LEU n 1 694 LEU n 1 695 LYS n 1 696 SER n 1 697 ILE n 1 698 GLN n 1 699 LEU n 1 700 THR n 1 701 GLN n 1 702 ASP n 1 703 SER n 1 704 PRO n 1 705 HIS n 1 706 VAL n 1 707 PRO n 1 708 VAL n 1 709 HIS n 1 710 PHE n 1 711 LYS n 1 712 PHE n 1 713 LEU n 1 714 LYS n 1 715 TYR n 1 716 GLY n 1 717 VAL n 1 718 ARG n 1 719 SER n 1 720 HIS n 1 721 GLY n 1 722 ASP n 1 723 ARG n 1 724 SER n 1 725 GLY n 1 726 ALA n 1 727 TYR n 1 728 LEU n 1 729 PHE n 1 730 LEU n 1 731 PRO n 1 732 ASN n 1 733 GLY n 1 734 PRO n 1 735 ALA n 1 736 SER n 1 737 PRO n 1 738 VAL n 1 739 GLU n 1 740 LEU n 1 741 GLY n 1 742 GLN n 1 743 PRO n 1 744 VAL n 1 745 VAL n 1 746 LEU n 1 747 VAL n 1 748 THR n 1 749 LYS n 1 750 GLY n 1 751 LYS n 1 752 LEU n 1 753 GLU n 1 754 SER n 1 755 SER n 1 756 VAL n 1 757 SER n 1 758 VAL n 1 759 GLY n 1 760 LEU n 1 761 PRO n 1 762 SER n 1 763 VAL n 1 764 VAL n 1 765 HIS n 1 766 GLN n 1 767 THR n 1 768 ILE n 1 769 MET n 1 770 ARG n 1 771 GLY n 1 772 GLY n 1 773 ALA n 1 774 PRO n 1 775 GLU n 1 776 ILE n 1 777 ARG n 1 778 ASN n 1 779 LEU n 1 780 VAL n 1 781 ASP n 1 782 ILE n 1 783 GLY n 1 784 SER n 1 785 LEU n 1 786 ASP n 1 787 ASN n 1 788 THR n 1 789 GLU n 1 790 ILE n 1 791 VAL n 1 792 MET n 1 793 ARG n 1 794 LEU n 1 795 GLU n 1 796 THR n 1 797 HIS n 1 798 ILE n 1 799 ASP n 1 800 SER n 1 801 GLY n 1 802 ASP n 1 803 ILE n 1 804 PHE n 1 805 TYR n 1 806 THR n 1 807 ASP n 1 808 LEU n 1 809 ASN n 1 810 GLY n 1 811 LEU n 1 812 GLN n 1 813 PHE n 1 814 ILE n 1 815 LYS n 1 816 ARG n 1 817 ARG n 1 818 ARG n 1 819 LEU n 1 820 ASP n 1 821 LYS n 1 822 LEU n 1 823 PRO n 1 824 LEU n 1 825 GLN n 1 826 ALA n 1 827 ASN n 1 828 TYR n 1 829 TYR n 1 830 PRO n 1 831 ILE n 1 832 PRO n 1 833 SER n 1 834 GLY n 1 835 MET n 1 836 PHE n 1 837 ILE n 1 838 GLU n 1 839 ASP n 1 840 ALA n 1 841 ASN n 1 842 THR n 1 843 ARG n 1 844 LEU n 1 845 THR n 1 846 LEU n 1 847 LEU n 1 848 THR n 1 849 GLY n 1 850 GLN n 1 851 PRO n 1 852 LEU n 1 853 GLY n 1 854 GLY n 1 855 SER n 1 856 SER n 1 857 LEU n 1 858 ALA n 1 859 SER n 1 860 GLY n 1 861 GLU n 1 862 LEU n 1 863 GLU n 1 864 ILE n 1 865 MET n 1 866 GLN n 1 867 ASP n 1 868 ARG n 1 869 ARG n 1 870 LEU n 1 871 ALA n 1 872 SER n 1 873 ASP n 1 874 ASP n 1 875 GLU n 1 876 ARG n 1 877 GLY n 1 878 LEU n 1 879 GLY n 1 880 GLN n 1 881 GLY n 1 882 VAL n 1 883 LEU n 1 884 ASP n 1 885 ASN n 1 886 LYS n 1 887 PRO n 1 888 VAL n 1 889 LEU n 1 890 HIS n 1 891 ILE n 1 892 TYR n 1 893 ARG n 1 894 LEU n 1 895 VAL n 1 896 LEU n 1 897 GLU n 1 898 LYS n 1 899 VAL n 1 900 ASN n 1 901 ASN n 1 902 CYS n 1 903 VAL n 1 904 ARG n 1 905 PRO n 1 906 SER n 1 907 LYS n 1 908 LEU n 1 909 HIS n 1 910 PRO n 1 911 ALA n 1 912 GLY n 1 913 TYR n 1 914 LEU n 1 915 THR n 1 916 SER n 1 917 ALA n 1 918 ALA n 1 919 HIS n 1 920 LYS n 1 921 ALA n 1 922 SER n 1 923 GLN n 1 924 SER n 1 925 LEU n 1 926 LEU n 1 927 ASP n 1 928 PRO n 1 929 LEU n 1 930 ASP n 1 931 LYS n 1 932 PHE n 1 933 ILE n 1 934 PHE n 1 935 ALA n 1 936 GLU n 1 937 ASN n 1 938 GLU n 1 939 TRP n 1 940 ILE n 1 941 GLY n 1 942 ALA n 1 943 GLN n 1 944 GLY n 1 945 GLN n 1 946 PHE n 1 947 GLY n 1 948 GLY n 1 949 ASP n 1 950 HIS n 1 951 PRO n 1 952 SER n 1 953 ALA n 1 954 ARG n 1 955 GLU n 1 956 ASP n 1 957 LEU n 1 958 ASP n 1 959 VAL n 1 960 SER n 1 961 VAL n 1 962 MET n 1 963 ARG n 1 964 ARG n 1 965 LEU n 1 966 THR n 1 967 LYS n 1 968 SER n 1 969 SER n 1 970 ALA n 1 971 LYS n 1 972 THR n 1 973 GLN n 1 974 ARG n 1 975 VAL n 1 976 GLY n 1 977 TYR n 1 978 VAL n 1 979 LEU n 1 980 HIS n 1 981 ARG n 1 982 THR n 1 983 ASN n 1 984 LEU n 1 985 MET n 1 986 GLN n 1 987 CYS n 1 988 GLY n 1 989 THR n 1 990 PRO n 1 991 GLU n 1 992 GLU n 1 993 HIS n 1 994 THR n 1 995 GLN n 1 996 LYS n 1 997 LEU n 1 998 ASP n 1 999 VAL n 1 1000 CYS n 1 1001 HIS n 1 1002 LEU n 1 1003 LEU n 1 1004 PRO n 1 1005 ASN n 1 1006 VAL n 1 1007 ALA n 1 1008 ARG n 1 1009 CYS n 1 1010 GLU n 1 1011 ARG n 1 1012 THR n 1 1013 THR n 1 1014 LEU n 1 1015 THR n 1 1016 PHE n 1 1017 LEU n 1 1018 GLN n 1 1019 ASN n 1 1020 LEU n 1 1021 GLU n 1 1022 HIS n 1 1023 LEU n 1 1024 ASP n 1 1025 GLY n 1 1026 MET n 1 1027 VAL n 1 1028 ALA n 1 1029 PRO n 1 1030 GLU n 1 1031 VAL n 1 1032 CYS n 1 1033 PRO n 1 1034 MET n 1 1035 GLU n 1 1036 THR n 1 1037 ALA n 1 1038 ALA n 1 1039 TYR n 1 1040 VAL n 1 1041 SER n 1 1042 SER n 1 1043 HIS n 1 1044 SER n 1 1045 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'fruit fly' _entity_src_gen.gene_src_genus Drosophila _entity_src_gen.pdbx_gene_src_gene 'ALPHA-MAN-II OR GMII OR CG18474/CG18802/CG8139' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 7227 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'fruit fly' _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus Drosophila _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain S2 _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MAN2_DROME _struct_ref.pdbx_db_accession Q24451 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHND PGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEAN SHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWD NKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTN VLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSD NYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQE ALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFY VSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLL RKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPN GPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQ FIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIY RLVLEKVNNCVRPSELHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKT QRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS ; _struct_ref.pdbx_align_begin 76 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 1QX1 _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 13 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 1045 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q24451 _struct_ref_seq.db_align_beg 76 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 1108 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 13 _struct_ref_seq.pdbx_auth_seq_align_end 1045 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 1QX1 ARG A 1 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 1 1 1 1QX1 SER A 2 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 2 2 1 1QX1 SER A 3 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 3 3 1 1QX1 HIS A 4 ? UNP Q24451 ? ? 'EXPRESSION TAG' 4 4 1 1QX1 HIS A 5 ? UNP Q24451 ? ? 'EXPRESSION TAG' 5 5 1 1QX1 HIS A 6 ? UNP Q24451 ? ? 'EXPRESSION TAG' 6 6 1 1QX1 HIS A 7 ? UNP Q24451 ? ? 'EXPRESSION TAG' 7 7 1 1QX1 HIS A 8 ? UNP Q24451 ? ? 'EXPRESSION TAG' 8 8 1 1QX1 HIS A 9 ? UNP Q24451 ? ? 'EXPRESSION TAG' 9 9 1 1QX1 GLY A 10 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 10 10 1 1QX1 GLU A 11 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 11 11 1 1QX1 PHE A 12 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 12 12 1 1QX1 ASN A 341 ? UNP Q24451 ASP 404 ENGINEERED 341 13 1 1QX1 LYS A 907 ? UNP Q24451 GLU 970 'SEE REMARK 999' 907 14 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FMF non-polymer . '2-DEOXY-2-FLUOROHEXOPYRANOSYL FLUORIDE' '2-DEOXY-2-FLUORO-ALPHA-D-MANNOSYL FLUORIDE' 'C6 H10 F2 O4' 184.138 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MPD non-polymer . '(4S)-2-METHYL-2,4-PENTANEDIOL' ? 'C6 H14 O2' 118.174 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 1QX1 _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.20 _exptl_crystal.density_percent_sol 44.06 _exptl_crystal.description ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7 _exptl_crystal_grow.pdbx_details 'PEG 6000, MPD, Tris, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 298K' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2002-03-22 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'Si(111)' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.95 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'CHESS BEAMLINE F1' _diffrn_source.pdbx_synchrotron_site CHESS _diffrn_source.pdbx_synchrotron_beamline F1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.95 # _reflns.entry_id 1QX1 _reflns.observed_criterion_sigma_I 2.0 _reflns.observed_criterion_sigma_F 2.9 _reflns.d_resolution_low 30 _reflns.d_resolution_high 1.3 _reflns.number_obs 246051 _reflns.number_all 258750 _reflns.percent_possible_obs 95.3 _reflns.pdbx_Rmerge_I_obs 0.106 _reflns.pdbx_Rsym_value 0.106 _reflns.pdbx_netI_over_sigmaI 14.7 _reflns.B_iso_Wilson_estimate 12.9 _reflns.pdbx_redundancy 6.5 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.3 _reflns_shell.d_res_low 1.38 _reflns_shell.percent_possible_all 83.2 _reflns_shell.Rmerge_I_obs 0.586 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 2.9 _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 1QX1 _refine.ls_number_reflns_obs 239861 _refine.ls_number_reflns_all 258759 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.0 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 29.23 _refine.ls_d_res_high 1.30 _refine.ls_percent_reflns_obs 92.7 _refine.ls_R_factor_obs 0.17 _refine.ls_R_factor_all 0.17 _refine.ls_R_factor_R_work 0.17 _refine.ls_R_factor_R_free 0.189 _refine.ls_R_factor_R_free_error 0.004 _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 0.9 _refine.ls_number_reflns_R_free 2180 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 16.1 _refine.aniso_B[1][1] 0.08 _refine.aniso_B[2][2] 0.22 _refine.aniso_B[3][3] -0.30 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'FLAT MODEL' _refine.solvent_model_param_ksol 0.369171 _refine.solvent_model_param_bsol 54.9168 _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ? _refine.pdbx_starting_model 1HTY _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 1QX1 _refine_analyze.Luzzati_coordinate_error_obs ? _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_coordinate_error_free 0.15 _refine_analyze.Luzzati_sigma_a_free 0.12 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8181 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 34 _refine_hist.number_atoms_solvent 1042 _refine_hist.number_atoms_total 9257 _refine_hist.d_res_high 1.30 _refine_hist.d_res_low 29.23 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d 0.022 ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg 2.0 ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d 25.4 ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d 1.42 ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it 1.56 1.50 ? ? 'X-RAY DIFFRACTION' ? c_mcangle_it 2.16 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scbond_it 2.90 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scangle_it 4.03 2.50 ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 6 _refine_ls_shell.d_res_high 1.30 _refine_ls_shell.d_res_low 1.38 _refine_ls_shell.number_reflns_R_work 35149 _refine_ls_shell.R_factor_R_work 0.231 _refine_ls_shell.percent_reflns_obs 83.2 _refine_ls_shell.R_factor_R_free 0.263 _refine_ls_shell.R_factor_R_free_error 0.014 _refine_ls_shell.percent_reflns_R_free 1.0 _refine_ls_shell.number_reflns_R_free 352 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.number_reflns_all ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.R_factor_all ? # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 PROTEIN_REP.PARAM PROTEIN_REP.TOP 'X-RAY DIFFRACTION' 2 CARBOHYDRATE.PARAM CARBOHYDRATE.TOP 'X-RAY DIFFRACTION' 3 CIS_PEPTIDE.PARAM CIS_PEPTIDE.TOP 'X-RAY DIFFRACTION' 4 WATER_REP.PARAM WATER_REP.TOP 'X-RAY DIFFRACTION' 5 ION.PARAM ION.TOP 'X-RAY DIFFRACTION' # _struct.entry_id 1QX1 _struct.title 'Golgi alpha-mannosidase II D341N mutant complex with 2-F-mannosyl-F' _struct.pdbx_descriptor 'Alpha-mannosidase II (E.C.3.2.1.114)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 1QX1 _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'Glycosyl hydrolase family 38, covalent catalytic intermediate, HYDROLASE' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 6 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 MET A 45 ? MET A 52 ? MET A 45 MET A 52 1 ? 8 HELX_P HELX_P2 2 ASP A 71 ? TYR A 75 ? ASP A 71 TYR A 75 5 ? 5 HELX_P HELX_P3 3 THR A 98 ? ASP A 106 ? THR A 98 ASP A 106 1 ? 9 HELX_P HELX_P4 4 ASP A 106 ? ASN A 121 ? ASP A 106 ASN A 121 1 ? 16 HELX_P HELX_P5 5 GLU A 130 ? LEU A 141 ? GLU A 130 LEU A 141 1 ? 12 HELX_P HELX_P6 6 GLY A 142 ? ASN A 155 ? GLY A 142 ASN A 155 1 ? 14 HELX_P HELX_P7 7 HIS A 174 ? ASN A 194 ? HIS A 174 ASN A 194 1 ? 21 HELX_P HELX_P8 8 PRO A 210 ? LYS A 218 ? PRO A 210 LYS A 218 1 ? 9 HELX_P HELX_P9 9 HIS A 230 ? GLN A 240 ? HIS A 230 GLN A 240 1 ? 11 HELX_P HELX_P10 10 ASP A 270 ? THR A 274 ? ASP A 270 THR A 274 5 ? 5 HELX_P HELX_P11 11 ASP A 278 ? CYS A 283 ? ASP A 278 CYS A 283 1 ? 6 HELX_P HELX_P12 12 GLN A 284 ? MET A 290 ? GLN A 284 MET A 290 5 ? 7 HELX_P HELX_P13 13 ASN A 310 ? GLU A 327 ? ASN A 310 GLU A 327 1 ? 18 HELX_P HELX_P14 14 GLN A 346 ? GLN A 367 ? GLN A 346 GLN A 367 1 ? 22 HELX_P HELX_P15 15 ALA A 368 ? PHE A 370 ? ALA A 368 PHE A 370 5 ? 3 HELX_P HELX_P16 16 THR A 378 ? ALA A 392 ? THR A 378 ALA A 392 1 ? 15 HELX_P HELX_P17 17 SER A 416 ? THR A 420 ? SER A 416 THR A 420 5 ? 5 HELX_P HELX_P18 18 ARG A 422 ? TRP A 445 ? ARG A 422 TRP A 445 1 ? 24 HELX_P HELX_P19 19 ASP A 449 ? ALA A 452 ? ASP A 449 ALA A 452 5 ? 4 HELX_P HELX_P20 20 ARG A 453 ? GLN A 469 ? ARG A 453 GLN A 469 1 ? 17 HELX_P HELX_P21 21 LYS A 479 ? LEU A 509 ? LYS A 479 LEU A 509 1 ? 31 HELX_P HELX_P22 22 PRO A 823 ? TYR A 828 ? PRO A 823 TYR A 828 5 ? 6 HELX_P HELX_P23 23 THR A 915 ? ASP A 927 ? THR A 915 ASP A 927 1 ? 13 HELX_P HELX_P24 24 ASP A 998 ? LEU A 1002 ? ASP A 998 LEU A 1002 5 ? 5 HELX_P HELX_P25 25 ASP A 1024 ? VAL A 1027 ? ASP A 1024 VAL A 1027 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 31 SG ? ? ? 1_555 A CYS 1032 SG ? ? A CYS 31 A CYS 1032 1_555 ? ? ? ? ? ? ? 2.054 ? disulf2 disulf ? ? A CYS 275 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 275 A CYS 282 1_555 ? ? ? ? ? ? ? 2.044 ? disulf3 disulf ? ? A CYS 283 SG ? ? ? 1_555 A CYS 297 SG ? ? A CYS 283 A CYS 297 1_555 ? ? ? ? ? ? ? 2.100 ? disulf4 disulf ? ? A CYS 902 SG ? ? ? 1_555 A CYS 987 SG ? ? A CYS 902 A CYS 987 1_555 ? ? ? ? ? ? ? 2.068 ? disulf5 disulf ? ? A CYS 1000 SG ? ? ? 1_555 A CYS 1009 SG ? ? A CYS 1000 A CYS 1009 1_555 ? ? ? ? ? ? ? 2.014 ? covale1 covale ? ? A ASN 194 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 194 A NAG 2001 1_555 ? ? ? ? ? ? ? 1.891 ? covale2 covale ? ? A ASP 204 OD1 ? ? ? 1_555 D FMF . C1 A ? A ASP 204 A FMF 2003 1_555 ? ? ? ? ? ? ? 2.173 ? covale3 covale ? ? A ASP 204 OD1 ? ? ? 1_555 D FMF . C1 B ? A ASP 204 A FMF 2003 1_555 ? ? ? ? ? ? ? 1.503 ? metalc1 metalc ? ? C ZN . ZN ? ? ? 1_555 A ASP 92 OD1 ? ? A ZN 2004 A ASP 92 1_555 ? ? ? ? ? ? ? 2.044 ? metalc2 metalc ? ? C ZN . ZN ? ? ? 1_555 D FMF . F2 B ? A ZN 2004 A FMF 2003 1_555 ? ? ? ? ? ? ? 2.484 ? metalc3 metalc ? ? C ZN . ZN ? ? ? 1_555 D FMF . O3 A ? A ZN 2004 A FMF 2003 1_555 ? ? ? ? ? ? ? 2.078 ? metalc4 metalc ? ? C ZN . ZN ? ? ? 1_555 D FMF . O3 B ? A ZN 2004 A FMF 2003 1_555 ? ? ? ? ? ? ? 2.197 ? metalc5 metalc ? ? C ZN . ZN ? ? ? 1_555 A HIS 471 NE2 ? ? A ZN 2004 A HIS 471 1_555 ? ? ? ? ? ? ? 2.081 ? metalc6 metalc ? ? C ZN . ZN ? ? ? 1_555 A HIS 90 NE2 ? ? A ZN 2004 A HIS 90 1_555 ? ? ? ? ? ? ? 2.072 ? metalc7 metalc ? ? C ZN . ZN ? ? ? 1_555 D FMF . F2 A ? A ZN 2004 A FMF 2003 1_555 ? ? ? ? ? ? ? 2.551 ? metalc8 metalc ? ? C ZN . ZN ? ? ? 1_555 A ASP 204 OD1 ? ? A ZN 2004 A ASP 204 1_555 ? ? ? ? ? ? ? 2.696 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 405 A . ? PHE 405 A THR 406 A ? THR 406 A 1 -2.26 2 TRP 531 A . ? TRP 531 A PRO 532 A ? PRO 532 A 1 -1.19 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 6 ? B ? 3 ? C ? 2 ? D ? 2 ? E ? 6 ? F ? 5 ? G ? 5 ? H ? 12 ? I ? 5 ? J ? 8 ? K ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? anti-parallel A 4 5 ? parallel A 5 6 ? parallel B 1 2 ? parallel B 2 3 ? parallel C 1 2 ? parallel D 1 2 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? anti-parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? parallel H 1 2 ? parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel H 6 7 ? anti-parallel H 7 8 ? anti-parallel H 8 9 ? anti-parallel H 9 10 ? anti-parallel H 10 11 ? anti-parallel H 11 12 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? anti-parallel J 6 7 ? anti-parallel J 7 8 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 VAL A 43 ? GLN A 44 ? VAL A 43 GLN A 44 A 2 THR A 399 ? SER A 401 ? THR A 399 SER A 401 A 3 GLU A 244 ? TRP A 247 ? GLU A 244 TRP A 247 A 4 LEU A 259 ? MET A 263 ? LEU A 259 MET A 263 A 5 ASN A 223 ? ILE A 226 ? ASN A 223 ILE A 226 A 6 ALA A 199 ? ALA A 202 ? ALA A 199 ALA A 202 B 1 VAL A 333 ? ASN A 341 ? VAL A 333 ASN A 341 B 2 LEU A 81 ? HIS A 90 ? LEU A 81 HIS A 90 B 3 VAL A 372 ? PHE A 376 ? VAL A 372 PHE A 376 C 1 PHE A 126 ? TRP A 128 ? PHE A 126 TRP A 128 C 2 LEU A 158 ? PHE A 160 ? LEU A 158 PHE A 160 D 1 ALA A 408 ? ARG A 410 ? ALA A 408 ARG A 410 D 2 ASN A 413 ? TYR A 414 ? ASN A 413 TYR A 414 E 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 E 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 E 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 E 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 E 5 VAL A 578 ? ASP A 582 ? VAL A 578 ASP A 582 E 6 PRO A 587 ? VAL A 588 ? PRO A 587 VAL A 588 F 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 F 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 F 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 F 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 F 5 GLN A 945 ? PHE A 946 ? GLN A 945 PHE A 946 G 1 THR A 542 ? ILE A 543 ? THR A 542 ILE A 543 G 2 ARG A 565 ? VAL A 573 ? ARG A 565 VAL A 573 G 3 THR A 606 ? VAL A 624 ? THR A 606 VAL A 624 G 4 ALA A 590 ? ASP A 601 ? ALA A 590 ASP A 601 G 5 THR A 644 ? TYR A 646 ? THR A 644 TYR A 646 H 1 LYS A 669 ? GLY A 671 ? LYS A 669 GLY A 671 H 2 SER A 648 ? LEU A 652 ? SER A 648 LEU A 652 H 3 VAL A 745 ? LYS A 749 ? VAL A 745 LYS A 749 H 4 SER A 754 ? LEU A 760 ? SER A 754 LEU A 760 H 5 VAL A 763 ? MET A 769 ? VAL A 763 MET A 769 H 6 GLU A 775 ? VAL A 780 ? GLU A 775 VAL A 780 H 7 VAL A 888 ? LYS A 898 ? VAL A 888 LYS A 898 H 8 THR A 842 ? THR A 848 ? THR A 842 THR A 848 H 9 GLY A 834 ? GLU A 838 ? GLY A 834 GLU A 838 H 10 ILE A 803 ? LEU A 808 ? ILE A 803 LEU A 808 H 11 GLN A 812 ? ARG A 817 ? GLN A 812 ARG A 817 H 12 ALA A 911 ? GLY A 912 ? ALA A 911 GLY A 912 I 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 I 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 I 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 I 4 HIS A 705 ? TYR A 715 ? HIS A 705 TYR A 715 I 5 SER A 736 ? PRO A 737 ? SER A 736 PRO A 737 J 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 J 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 J 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 J 4 HIS A 705 ? TYR A 715 ? HIS A 705 TYR A 715 J 5 THR A 788 ? THR A 796 ? THR A 788 THR A 796 J 6 GLU A 861 ? ARG A 869 ? GLU A 861 ARG A 869 J 7 LEU A 852 ? SER A 855 ? LEU A 852 SER A 855 J 8 TYR A 829 ? ILE A 831 ? TYR A 829 ILE A 831 K 1 LEU A 957 ? ARG A 964 ? LEU A 957 ARG A 964 K 2 GLN A 973 ? ARG A 981 ? GLN A 973 ARG A 981 K 3 THR A 1036 ? HIS A 1043 ? THR A 1036 HIS A 1043 K 4 VAL A 1006 ? THR A 1012 ? VAL A 1006 THR A 1012 K 5 ASN A 1019 ? HIS A 1022 ? ASN A 1019 HIS A 1022 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 43 ? N VAL A 43 O SER A 401 ? O SER A 401 A 2 3 O LEU A 400 ? O LEU A 400 N LEU A 246 ? N LEU A 246 A 3 4 N PHE A 245 ? N PHE A 245 O THR A 261 ? O THR A 261 A 4 5 O HIS A 262 ? O HIS A 262 N MET A 224 ? N MET A 224 A 5 6 O LEU A 225 ? O LEU A 225 N ALA A 202 ? N ALA A 202 B 1 2 O LEU A 334 ? O LEU A 334 N LYS A 82 ? N LYS A 82 B 2 3 N VAL A 85 ? N VAL A 85 O GLN A 375 ? O GLN A 375 C 1 2 N PHE A 126 ? N PHE A 126 O GLU A 159 ? O GLU A 159 D 1 2 N ARG A 410 ? N ARG A 410 O ASN A 413 ? O ASN A 413 E 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 E 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 E 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 E 4 5 O VAL A 633 ? O VAL A 633 N THR A 581 ? N THR A 581 E 5 6 N VAL A 580 ? N VAL A 580 O VAL A 588 ? O VAL A 588 F 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 F 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 F 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 F 4 5 N LEU A 629 ? N LEU A 629 O PHE A 946 ? O PHE A 946 G 1 2 N ILE A 543 ? N ILE A 543 O TYR A 572 ? O TYR A 572 G 2 3 N GLN A 567 ? N GLN A 567 O ALA A 622 ? O ALA A 622 G 3 4 O GLN A 610 ? O GLN A 610 N SER A 597 ? N SER A 597 G 4 5 N VAL A 592 ? N VAL A 592 O SER A 645 ? O SER A 645 H 1 2 O LYS A 669 ? O LYS A 669 N LEU A 651 ? N LEU A 651 H 2 3 N LEU A 652 ? N LEU A 652 O VAL A 745 ? O VAL A 745 H 3 4 N LEU A 746 ? N LEU A 746 O SER A 757 ? O SER A 757 H 4 5 N SER A 754 ? N SER A 754 O MET A 769 ? O MET A 769 H 5 6 N ILE A 768 ? N ILE A 768 O GLU A 775 ? O GLU A 775 H 6 7 N VAL A 780 ? N VAL A 780 O VAL A 888 ? O VAL A 888 H 7 8 O VAL A 895 ? O VAL A 895 N THR A 845 ? N THR A 845 H 8 9 O LEU A 846 ? O LEU A 846 N MET A 835 ? N MET A 835 H 9 10 O PHE A 836 ? O PHE A 836 N TYR A 805 ? N TYR A 805 H 10 11 N PHE A 804 ? N PHE A 804 O ARG A 816 ? O ARG A 816 H 11 12 N PHE A 813 ? N PHE A 813 O GLY A 912 ? O GLY A 912 I 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 I 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 I 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 I 4 5 N LYS A 714 ? N LYS A 714 O SER A 736 ? O SER A 736 J 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 J 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 J 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 J 4 5 N LYS A 711 ? N LYS A 711 O ARG A 793 ? O ARG A 793 J 5 6 N ILE A 790 ? N ILE A 790 O GLN A 866 ? O GLN A 866 J 6 7 O GLU A 863 ? O GLU A 863 N SER A 855 ? N SER A 855 J 7 8 O GLY A 854 ? O GLY A 854 N TYR A 829 ? N TYR A 829 K 1 2 N ARG A 963 ? N ARG A 963 O GLY A 976 ? O GLY A 976 K 2 3 N TYR A 977 ? N TYR A 977 O TYR A 1039 ? O TYR A 1039 K 3 4 O SER A 1042 ? O SER A 1042 N ARG A 1008 ? N ARG A 1008 K 4 5 N ARG A 1011 ? N ARG A 1011 O LEU A 1020 ? O LEU A 1020 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 2001' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE ZN A 2004' AC3 Software ? ? ? ? 15 'BINDING SITE FOR RESIDUE FMF A 2003' AC4 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE MPD A 2002' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 2 ASN A 194 ? ASN A 194 . ? 1_555 ? 2 AC1 2 HOH F . ? HOH A 2914 . ? 1_555 ? 3 AC2 5 HIS A 90 ? HIS A 90 . ? 1_555 ? 4 AC2 5 ASP A 92 ? ASP A 92 . ? 1_555 ? 5 AC2 5 ASP A 204 ? ASP A 204 . ? 1_555 ? 6 AC2 5 HIS A 471 ? HIS A 471 . ? 1_555 ? 7 AC2 5 FMF D . ? FMF A 2003 . ? 1_555 ? 8 AC3 15 HIS A 90 ? HIS A 90 . ? 1_555 ? 9 AC3 15 ASP A 92 ? ASP A 92 . ? 1_555 ? 10 AC3 15 TRP A 95 ? TRP A 95 . ? 1_555 ? 11 AC3 15 ASP A 204 ? ASP A 204 . ? 1_555 ? 12 AC3 15 ARG A 228 ? ARG A 228 . ? 1_555 ? 13 AC3 15 TYR A 269 ? TYR A 269 . ? 1_555 ? 14 AC3 15 TRP A 415 ? TRP A 415 . ? 1_555 ? 15 AC3 15 HIS A 471 ? HIS A 471 . ? 1_555 ? 16 AC3 15 ASP A 472 ? ASP A 472 . ? 1_555 ? 17 AC3 15 TYR A 727 ? TYR A 727 . ? 1_555 ? 18 AC3 15 ARG A 876 ? ARG A 876 . ? 1_555 ? 19 AC3 15 ZN C . ? ZN A 2004 . ? 1_555 ? 20 AC3 15 HOH F . ? HOH A 2876 . ? 1_555 ? 21 AC3 15 HOH F . ? HOH A 2895 . ? 1_555 ? 22 AC3 15 HOH F . ? HOH A 3046 . ? 1_555 ? 23 AC4 7 LYS A 63 ? LYS A 63 . ? 1_555 ? 24 AC4 7 GLN A 64 ? GLN A 64 . ? 1_555 ? 25 AC4 7 HIS A 273 ? HIS A 273 . ? 1_555 ? 26 AC4 7 HOH F . ? HOH A 2152 . ? 1_555 ? 27 AC4 7 HOH F . ? HOH A 2622 . ? 1_555 ? 28 AC4 7 HOH F . ? HOH A 2693 . ? 1_555 ? 29 AC4 7 HOH F . ? HOH A 2844 . ? 1_555 ? # _database_PDB_matrix.entry_id 1QX1 _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 1QX1 _atom_sites.fract_transf_matrix[1][1] 0.014483 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009105 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007199 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C F N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . CYS A 1 31 ? 44.269 36.133 -19.178 1.00 27.01 ? 31 CYS A N 1 ATOM 2 C CA . CYS A 1 31 ? 43.568 37.380 -18.707 1.00 21.20 ? 31 CYS A CA 1 ATOM 3 C C . CYS A 1 31 ? 42.080 37.186 -18.792 1.00 21.87 ? 31 CYS A C 1 ATOM 4 O O . CYS A 1 31 ? 41.594 36.645 -19.807 1.00 24.89 ? 31 CYS A O 1 ATOM 5 C CB . CYS A 1 31 ? 43.868 38.556 -19.610 1.00 20.89 ? 31 CYS A CB 1 ATOM 6 S SG . CYS A 1 31 ? 45.571 39.183 -19.580 1.00 25.51 ? 31 CYS A SG 1 ATOM 7 N N . GLN A 1 32 ? 41.351 37.644 -17.784 1.00 19.48 ? 32 GLN A N 1 ATOM 8 C CA . GLN A 1 32 ? 39.883 37.602 -17.781 1.00 19.86 ? 32 GLN A CA 1 ATOM 9 C C . GLN A 1 32 ? 39.344 38.522 -18.872 1.00 16.99 ? 32 GLN A C 1 ATOM 10 O O . GLN A 1 32 ? 39.916 39.594 -19.170 1.00 17.18 ? 32 GLN A O 1 ATOM 11 C CB . GLN A 1 32 ? 39.286 38.194 -16.483 1.00 21.82 ? 32 GLN A CB 1 ATOM 12 C CG . GLN A 1 32 ? 39.461 37.381 -15.212 1.00 27.73 ? 32 GLN A CG 1 ATOM 13 C CD . GLN A 1 32 ? 38.379 37.714 -14.156 1.00 31.13 ? 32 GLN A CD 1 ATOM 14 O OE1 . GLN A 1 32 ? 37.266 37.207 -14.226 1.00 30.18 ? 32 GLN A OE1 1 ATOM 15 N NE2 . GLN A 1 32 ? 38.711 38.572 -13.179 1.00 30.10 ? 32 GLN A NE2 1 ATOM 16 N N . ASP A 1 33 ? 38.216 38.142 -19.440 1.00 19.96 ? 33 ASP A N 1 ATOM 17 C CA . ASP A 1 33 ? 37.569 38.950 -20.477 1.00 14.99 ? 33 ASP A CA 1 ATOM 18 C C . ASP A 1 33 ? 36.648 39.931 -19.721 1.00 18.83 ? 33 ASP A C 1 ATOM 19 O O . ASP A 1 33 ? 35.686 39.543 -19.080 1.00 21.14 ? 33 ASP A O 1 ATOM 20 C CB . ASP A 1 33 ? 36.791 37.993 -21.417 1.00 16.75 ? 33 ASP A CB 1 ATOM 21 C CG . ASP A 1 33 ? 36.087 38.683 -22.568 1.00 20.37 ? 33 ASP A CG 1 ATOM 22 O OD1 . ASP A 1 33 ? 35.901 38.001 -23.598 1.00 22.00 ? 33 ASP A OD1 1 ATOM 23 O OD2 . ASP A 1 33 ? 35.634 39.850 -22.472 1.00 19.28 ? 33 ASP A OD2 1 ATOM 24 N N . VAL A 1 34 ? 36.918 41.220 -19.834 1.00 12.41 ? 34 VAL A N 1 ATOM 25 C CA . VAL A 1 34 ? 36.160 42.213 -19.080 1.00 11.11 ? 34 VAL A CA 1 ATOM 26 C C . VAL A 1 34 ? 34.953 42.771 -19.813 1.00 10.53 ? 34 VAL A C 1 ATOM 27 O O . VAL A 1 34 ? 34.227 43.658 -19.319 1.00 10.67 ? 34 VAL A O 1 ATOM 28 C CB . VAL A 1 34 ? 37.102 43.370 -18.597 1.00 12.14 ? 34 VAL A CB 1 ATOM 29 C CG1 . VAL A 1 34 ? 38.311 42.797 -17.836 1.00 13.44 ? 34 VAL A CG1 1 ATOM 30 C CG2 . VAL A 1 34 ? 37.566 44.211 -19.807 1.00 11.72 ? 34 VAL A CG2 1 ATOM 31 N N . VAL A 1 35 ? 34.736 42.253 -21.031 1.00 11.17 ? 35 VAL A N 1 ATOM 32 C CA . VAL A 1 35 ? 33.634 42.710 -21.862 1.00 11.11 ? 35 VAL A CA 1 ATOM 33 C C . VAL A 1 35 ? 32.428 41.781 -22.053 1.00 10.88 ? 35 VAL A C 1 ATOM 34 O O . VAL A 1 35 ? 31.295 42.189 -22.006 1.00 12.02 ? 35 VAL A O 1 ATOM 35 C CB . VAL A 1 35 ? 34.165 43.030 -23.278 1.00 12.06 ? 35 VAL A CB 1 ATOM 36 C CG1 . VAL A 1 35 ? 33.030 43.499 -24.224 1.00 12.86 ? 35 VAL A CG1 1 ATOM 37 C CG2 . VAL A 1 35 ? 35.250 44.140 -23.174 1.00 12.62 ? 35 VAL A CG2 1 ATOM 38 N N . GLN A 1 36 ? 32.770 40.522 -22.298 1.00 12.94 ? 36 GLN A N 1 ATOM 39 C CA . GLN A 1 36 ? 31.775 39.521 -22.773 1.00 14.04 ? 36 GLN A CA 1 ATOM 40 C C . GLN A 1 36 ? 31.125 38.612 -21.781 1.00 19.76 ? 36 GLN A C 1 ATOM 41 O O . GLN A 1 36 ? 30.159 37.934 -22.126 1.00 23.65 ? 36 GLN A O 1 ATOM 42 C CB . GLN A 1 36 ? 32.491 38.698 -23.851 1.00 12.60 ? 36 GLN A CB 1 ATOM 43 C CG . GLN A 1 36 ? 33.060 39.558 -24.962 1.00 16.47 ? 36 GLN A CG 1 ATOM 44 C CD . GLN A 1 36 ? 33.557 38.736 -26.141 1.00 15.06 ? 36 GLN A CD 1 ATOM 45 O OE1 . GLN A 1 36 ? 32.828 38.585 -27.132 1.00 18.96 ? 36 GLN A OE1 1 ATOM 46 N NE2 . GLN A 1 36 ? 34.755 38.235 -26.058 1.00 16.30 ? 36 GLN A NE2 1 ATOM 47 N N . ASP A 1 37 ? 31.621 38.568 -20.557 1.00 17.69 ? 37 ASP A N 1 ATOM 48 C CA . ASP A 1 37 ? 31.087 37.706 -19.498 1.00 18.41 ? 37 ASP A CA 1 ATOM 49 C C . ASP A 1 37 ? 30.443 38.546 -18.378 1.00 16.31 ? 37 ASP A C 1 ATOM 50 O O . ASP A 1 37 ? 31.197 39.179 -17.584 1.00 24.21 ? 37 ASP A O 1 ATOM 51 C CB . ASP A 1 37 ? 32.247 36.866 -18.879 1.00 23.75 ? 37 ASP A CB 1 ATOM 52 C CG . ASP A 1 37 ? 32.908 35.900 -19.874 1.00 28.85 ? 37 ASP A CG 1 ATOM 53 O OD1 . ASP A 1 37 ? 32.171 35.281 -20.657 1.00 30.22 ? 37 ASP A OD1 1 ATOM 54 O OD2 . ASP A 1 37 ? 34.165 35.771 -19.843 1.00 27.76 ? 37 ASP A OD2 1 ATOM 55 N N . VAL A 1 38 ? 29.121 38.546 -18.293 1.00 15.77 ? 38 VAL A N 1 ATOM 56 C CA . VAL A 1 38 ? 28.445 39.307 -17.243 1.00 14.39 ? 38 VAL A CA 1 ATOM 57 C C . VAL A 1 38 ? 28.631 38.578 -15.901 1.00 16.52 ? 38 VAL A C 1 ATOM 58 O O . VAL A 1 38 ? 28.195 37.422 -15.737 1.00 16.43 ? 38 VAL A O 1 ATOM 59 C CB . VAL A 1 38 ? 26.943 39.439 -17.542 1.00 15.25 ? 38 VAL A CB 1 ATOM 60 C CG1 . VAL A 1 38 ? 26.233 40.190 -16.435 1.00 17.12 ? 38 VAL A CG1 1 ATOM 61 C CG2 . VAL A 1 38 ? 26.747 40.107 -18.943 1.00 16.36 ? 38 VAL A CG2 1 ATOM 62 N N . PRO A 1 39 ? 29.267 39.229 -14.900 1.00 13.54 ? 39 PRO A N 1 ATOM 63 C CA . PRO A 1 39 ? 29.451 38.539 -13.613 1.00 14.06 ? 39 PRO A CA 1 ATOM 64 C C . PRO A 1 39 ? 28.159 38.180 -12.967 1.00 13.51 ? 39 PRO A C 1 ATOM 65 O O . PRO A 1 39 ? 27.155 38.892 -13.031 1.00 14.03 ? 39 PRO A O 1 ATOM 66 C CB . PRO A 1 39 ? 30.219 39.570 -12.765 1.00 14.36 ? 39 PRO A CB 1 ATOM 67 C CG . PRO A 1 39 ? 31.018 40.362 -13.840 1.00 12.43 ? 39 PRO A CG 1 ATOM 68 C CD . PRO A 1 39 ? 29.971 40.547 -14.915 1.00 14.28 ? 39 PRO A CD 1 ATOM 69 N N . ASN A 1 40 ? 28.175 37.004 -12.312 1.00 14.27 ? 40 ASN A N 1 ATOM 70 C CA . ASN A 1 40 ? 27.001 36.593 -11.561 1.00 16.37 ? 40 ASN A CA 1 ATOM 71 C C . ASN A 1 40 ? 27.224 36.970 -10.081 1.00 15.75 ? 40 ASN A C 1 ATOM 72 O O . ASN A 1 40 ? 28.090 36.375 -9.402 1.00 17.45 ? 40 ASN A O 1 ATOM 73 C CB . ASN A 1 40 ? 26.805 35.065 -11.741 1.00 22.66 ? 40 ASN A CB 1 ATOM 74 C CG . ASN A 1 40 ? 25.751 34.508 -10.827 1.00 28.89 ? 40 ASN A CG 1 ATOM 75 O OD1 . ASN A 1 40 ? 24.713 35.130 -10.594 1.00 32.86 ? 40 ASN A OD1 1 ATOM 76 N ND2 . ASN A 1 40 ? 26.020 33.321 -10.273 1.00 35.19 ? 40 ASN A ND2 1 ATOM 77 N N . VAL A 1 41 ? 26.501 37.972 -9.606 1.00 12.70 ? 41 VAL A N 1 ATOM 78 C CA . VAL A 1 41 ? 26.669 38.424 -8.206 1.00 11.91 ? 41 VAL A CA 1 ATOM 79 C C . VAL A 1 41 ? 25.329 38.427 -7.512 1.00 12.93 ? 41 VAL A C 1 ATOM 80 O O . VAL A 1 41 ? 24.277 38.572 -8.132 1.00 14.45 ? 41 VAL A O 1 ATOM 81 C CB . VAL A 1 41 ? 27.288 39.871 -8.133 1.00 11.43 ? 41 VAL A CB 1 ATOM 82 C CG1 . VAL A 1 41 ? 28.730 39.807 -8.601 1.00 11.96 ? 41 VAL A CG1 1 ATOM 83 C CG2 . VAL A 1 41 ? 26.448 40.879 -9.016 1.00 12.29 ? 41 VAL A CG2 1 ATOM 84 N N . ASP A 1 42 ? 25.293 38.317 -6.189 1.00 11.23 ? 42 ASP A N 1 ATOM 85 C CA . ASP A 1 42 ? 24.023 38.344 -5.485 1.00 11.15 ? 42 ASP A CA 1 ATOM 86 C C . ASP A 1 42 ? 23.327 39.680 -5.501 1.00 11.41 ? 42 ASP A C 1 ATOM 87 O O . ASP A 1 42 ? 22.076 39.804 -5.500 1.00 13.07 ? 42 ASP A O 1 ATOM 88 C CB . ASP A 1 42 ? 24.228 37.915 -4.019 1.00 12.22 ? 42 ASP A CB 1 ATOM 89 C CG . ASP A 1 42 ? 24.761 36.509 -3.908 1.00 17.32 ? 42 ASP A CG 1 ATOM 90 O OD1 . ASP A 1 42 ? 24.081 35.571 -4.451 1.00 19.03 ? 42 ASP A OD1 1 ATOM 91 O OD2 . ASP A 1 42 ? 25.849 36.243 -3.335 1.00 14.88 ? 42 ASP A OD2 1 ATOM 92 N N . VAL A 1 43 ? 24.124 40.754 -5.431 1.00 10.31 ? 43 VAL A N 1 ATOM 93 C CA . VAL A 1 43 ? 23.579 42.131 -5.433 1.00 11.38 ? 43 VAL A CA 1 ATOM 94 C C . VAL A 1 43 ? 24.341 42.926 -6.499 1.00 10.03 ? 43 VAL A C 1 ATOM 95 O O . VAL A 1 43 ? 25.595 43.004 -6.442 1.00 10.68 ? 43 VAL A O 1 ATOM 96 C CB . VAL A 1 43 ? 23.794 42.858 -4.071 1.00 10.74 ? 43 VAL A CB 1 ATOM 97 C CG1 . VAL A 1 43 ? 23.186 44.288 -4.148 1.00 12.66 ? 43 VAL A CG1 1 ATOM 98 C CG2 . VAL A 1 43 ? 23.098 42.055 -2.929 1.00 14.50 ? 43 VAL A CG2 1 ATOM 99 N N . GLN A 1 44 ? 23.642 43.426 -7.506 1.00 8.87 ? 44 GLN A N 1 ATOM 100 C CA . GLN A 1 44 ? 24.276 44.276 -8.538 1.00 9.20 ? 44 GLN A CA 1 ATOM 101 C C . GLN A 1 44 ? 23.549 45.588 -8.393 1.00 9.60 ? 44 GLN A C 1 ATOM 102 O O . GLN A 1 44 ? 22.318 45.667 -8.539 1.00 9.65 ? 44 GLN A O 1 ATOM 103 C CB . GLN A 1 44 ? 24.109 43.619 -9.935 1.00 9.97 ? 44 GLN A CB 1 ATOM 104 C CG . GLN A 1 44 ? 25.212 44.058 -10.885 1.00 9.24 ? 44 GLN A CG 1 ATOM 105 C CD . GLN A 1 44 ? 25.271 45.566 -11.034 1.00 10.20 ? 44 GLN A CD 1 ATOM 106 O OE1 . GLN A 1 44 ? 24.270 46.194 -11.370 1.00 10.48 ? 44 GLN A OE1 1 ATOM 107 N NE2 . GLN A 1 44 ? 26.452 46.161 -10.736 1.00 9.36 ? 44 GLN A NE2 1 ATOM 108 N N . MET A 1 45 ? 24.268 46.665 -8.021 1.00 8.75 ? 45 MET A N 1 ATOM 109 C CA . MET A 1 45 ? 23.565 47.892 -7.632 1.00 8.39 ? 45 MET A CA 1 ATOM 110 C C . MET A 1 45 ? 22.672 48.538 -8.686 1.00 8.67 ? 45 MET A C 1 ATOM 111 O O . MET A 1 45 ? 21.685 49.150 -8.288 1.00 9.58 ? 45 MET A O 1 ATOM 112 C CB . MET A 1 45 ? 24.564 48.936 -7.033 1.00 8.90 ? 45 MET A CB 1 ATOM 113 C CG . MET A 1 45 ? 25.220 48.461 -5.715 1.00 9.29 ? 45 MET A CG 1 ATOM 114 S SD . MET A 1 45 ? 24.005 48.133 -4.423 1.00 11.75 ? 45 MET A SD 1 ATOM 115 C CE . MET A 1 45 ? 23.291 49.822 -4.279 1.00 13.59 ? 45 MET A CE 1 ATOM 116 N N . LEU A 1 46 ? 23.032 48.419 -9.952 1.00 9.06 ? 46 LEU A N 1 ATOM 117 C CA . LEU A 1 46 ? 22.156 49.026 -10.981 1.00 8.19 ? 46 LEU A CA 1 ATOM 118 C C . LEU A 1 46 ? 20.818 48.240 -11.026 1.00 10.44 ? 46 LEU A C 1 ATOM 119 O O . LEU A 1 46 ? 19.762 48.840 -11.154 1.00 10.92 ? 46 LEU A O 1 ATOM 120 C CB . LEU A 1 46 ? 22.858 48.998 -12.322 1.00 11.22 ? 46 LEU A CB 1 ATOM 121 C CG . LEU A 1 46 ? 22.065 49.710 -13.429 1.00 9.99 ? 46 LEU A CG 1 ATOM 122 C CD1 . LEU A 1 46 ? 22.096 51.262 -13.211 1.00 12.13 ? 46 LEU A CD1 1 ATOM 123 C CD2 . LEU A 1 46 ? 22.661 49.425 -14.786 1.00 13.58 ? 46 LEU A CD2 1 ATOM 124 N N . GLU A 1 47 ? 20.893 46.926 -10.869 1.00 10.09 ? 47 GLU A N 1 ATOM 125 C CA . GLU A 1 47 ? 19.711 46.068 -10.920 1.00 12.19 ? 47 GLU A CA 1 ATOM 126 C C . GLU A 1 47 ? 18.914 46.343 -9.668 1.00 11.66 ? 47 GLU A C 1 ATOM 127 O O . GLU A 1 47 ? 17.659 46.488 -9.701 1.00 12.79 ? 47 GLU A O 1 ATOM 128 C CB . GLU A 1 47 ? 20.140 44.624 -11.005 1.00 13.18 ? 47 GLU A CB 1 ATOM 129 C CG . GLU A 1 47 ? 18.929 43.652 -11.238 1.00 17.47 ? 47 GLU A CG 1 ATOM 130 C CD . GLU A 1 47 ? 18.143 43.302 -9.978 1.00 25.69 ? 47 GLU A CD 1 ATOM 131 O OE1 . GLU A 1 47 ? 18.652 43.424 -8.850 1.00 20.21 ? 47 GLU A OE1 1 ATOM 132 O OE2 . GLU A 1 47 ? 16.950 42.859 -10.096 1.00 27.63 ? 47 GLU A OE2 1 ATOM 133 N N . LEU A 1 48 ? 19.578 46.503 -8.514 1.00 11.11 ? 48 LEU A N 1 ATOM 134 C CA . LEU A 1 48 ? 18.858 46.814 -7.311 1.00 11.08 ? 48 LEU A CA 1 ATOM 135 C C . LEU A 1 48 ? 18.112 48.120 -7.414 1.00 11.04 ? 48 LEU A C 1 ATOM 136 O O . LEU A 1 48 ? 16.921 48.237 -7.034 1.00 13.67 ? 48 LEU A O 1 ATOM 137 C CB . LEU A 1 48 ? 19.837 46.839 -6.114 1.00 12.85 ? 48 LEU A CB 1 ATOM 138 C CG . LEU A 1 48 ? 19.196 47.068 -4.746 1.00 13.54 ? 48 LEU A CG 1 ATOM 139 C CD1 . LEU A 1 48 ? 18.127 45.987 -4.466 1.00 20.99 ? 48 LEU A CD1 1 ATOM 140 C CD2 . LEU A 1 48 ? 20.254 47.108 -3.637 1.00 18.95 ? 48 LEU A CD2 1 ATOM 141 N N . TYR A 1 49 ? 18.789 49.160 -7.937 1.00 10.57 ? 49 TYR A N 1 ATOM 142 C CA . TYR A 1 49 ? 18.142 50.462 -8.127 1.00 11.04 ? 49 TYR A CA 1 ATOM 143 C C . TYR A 1 49 ? 16.886 50.390 -9.038 1.00 11.59 ? 49 TYR A C 1 ATOM 144 O O . TYR A 1 49 ? 15.920 51.092 -8.784 1.00 12.62 ? 49 TYR A O 1 ATOM 145 C CB . TYR A 1 49 ? 19.164 51.455 -8.755 1.00 10.03 ? 49 TYR A CB 1 ATOM 146 C CG . TYR A 1 49 ? 19.775 52.367 -7.714 1.00 11.09 ? 49 TYR A CG 1 ATOM 147 C CD1 . TYR A 1 49 ? 20.240 51.875 -6.454 1.00 10.33 ? 49 TYR A CD1 1 ATOM 148 C CD2 . TYR A 1 49 ? 19.809 53.723 -7.952 1.00 11.31 ? 49 TYR A CD2 1 ATOM 149 C CE1 . TYR A 1 49 ? 20.677 52.720 -5.468 1.00 11.01 ? 49 TYR A CE1 1 ATOM 150 C CE2 . TYR A 1 49 ? 20.261 54.619 -6.951 1.00 11.48 ? 49 TYR A CE2 1 ATOM 151 C CZ . TYR A 1 49 ? 20.675 54.102 -5.701 1.00 9.23 ? 49 TYR A CZ 1 ATOM 152 O OH . TYR A 1 49 ? 21.034 54.917 -4.694 1.00 10.71 ? 49 TYR A OH 1 ATOM 153 N N . ASP A 1 50 ? 16.949 49.523 -10.048 1.00 11.59 ? 50 ASP A N 1 ATOM 154 C CA . ASP A 1 50 ? 15.827 49.425 -10.988 1.00 15.14 ? 50 ASP A CA 1 ATOM 155 C C . ASP A 1 50 ? 14.618 48.857 -10.254 1.00 16.50 ? 50 ASP A C 1 ATOM 156 O O . ASP A 1 50 ? 13.446 49.284 -10.541 1.00 16.18 ? 50 ASP A O 1 ATOM 157 C CB . ASP A 1 50 ? 16.256 48.514 -12.129 1.00 15.68 ? 50 ASP A CB 1 ATOM 158 C CG . ASP A 1 50 ? 15.456 48.728 -13.395 1.00 23.55 ? 50 ASP A CG 1 ATOM 159 O OD1 . ASP A 1 50 ? 15.551 47.837 -14.271 1.00 27.98 ? 50 ASP A OD1 1 ATOM 160 O OD2 . ASP A 1 50 ? 14.794 49.773 -13.523 1.00 24.33 ? 50 ASP A OD2 1 ATOM 161 N N . ARG A 1 51 ? 14.862 47.927 -9.328 1.00 15.80 ? 51 ARG A N 1 ATOM 162 C CA . ARG A 1 51 ? 13.753 47.297 -8.608 1.00 16.78 ? 51 ARG A CA 1 ATOM 163 C C . ARG A 1 51 ? 13.263 47.977 -7.343 1.00 17.35 ? 51 ARG A C 1 ATOM 164 O O . ARG A 1 51 ? 12.081 47.890 -6.991 1.00 19.50 ? 51 ARG A O 1 ATOM 165 C CB . ARG A 1 51 ? 14.057 45.782 -8.395 1.00 23.94 ? 51 ARG A CB 1 ATOM 166 C CG . ARG A 1 51 ? 15.242 45.370 -7.588 1.00 30.80 ? 51 ARG A CG 1 ATOM 167 C CD . ARG A 1 51 ? 15.251 43.830 -7.412 1.00 34.22 ? 51 ARG A CD 1 ATOM 168 N NE . ARG A 1 51 ? 15.940 43.528 -6.167 1.00 39.05 ? 51 ARG A NE 1 ATOM 169 C CZ . ARG A 1 51 ? 17.128 42.956 -6.111 1.00 38.17 ? 51 ARG A CZ 1 ATOM 170 N NH1 . ARG A 1 51 ? 17.724 42.614 -7.235 1.00 42.66 ? 51 ARG A NH1 1 ATOM 171 N NH2 . ARG A 1 51 ? 17.734 42.763 -4.946 1.00 43.50 ? 51 ARG A NH2 1 ATOM 172 N N . MET A 1 52 ? 14.111 48.701 -6.632 1.00 16.45 ? 52 MET A N 1 ATOM 173 C CA . MET A 1 52 ? 13.718 49.399 -5.406 1.00 17.58 ? 52 MET A CA 1 ATOM 174 C C . MET A 1 52 ? 12.714 50.520 -5.605 1.00 15.57 ? 52 MET A C 1 ATOM 175 O O . MET A 1 52 ? 12.803 51.246 -6.615 1.00 17.34 ? 52 MET A O 1 ATOM 176 C CB . MET A 1 52 ? 14.944 50.100 -4.776 1.00 16.68 ? 52 MET A CB 1 ATOM 177 C CG . MET A 1 52 ? 15.886 49.149 -4.146 1.00 15.49 ? 52 MET A CG 1 ATOM 178 S SD . MET A 1 52 ? 17.530 50.017 -3.679 1.00 20.86 ? 52 MET A SD 1 ATOM 179 C CE . MET A 1 52 ? 16.952 51.361 -2.655 1.00 17.61 ? 52 MET A CE 1 ATOM 180 N N A SER A 1 53 ? 11.846 50.755 -4.601 0.50 16.91 ? 53 SER A N 1 ATOM 181 N N B SER A 1 53 ? 11.846 50.755 -4.601 0.50 17.36 ? 53 SER A N 1 ATOM 182 C CA A SER A 1 53 ? 10.840 51.839 -4.702 0.50 18.17 ? 53 SER A CA 1 ATOM 183 C CA B SER A 1 53 ? 10.840 51.839 -4.702 0.50 19.18 ? 53 SER A CA 1 ATOM 184 C C A SER A 1 53 ? 11.272 53.172 -4.069 0.50 16.34 ? 53 SER A C 1 ATOM 185 C C B SER A 1 53 ? 11.272 53.172 -4.069 0.50 16.86 ? 53 SER A C 1 ATOM 186 O O A SER A 1 53 ? 10.671 54.225 -4.303 0.50 17.62 ? 53 SER A O 1 ATOM 187 O O B SER A 1 53 ? 10.671 54.225 -4.303 0.50 18.16 ? 53 SER A O 1 ATOM 188 C CB A SER A 1 53 ? 9.528 51.344 -4.070 0.50 18.69 ? 53 SER A CB 1 ATOM 189 C CB B SER A 1 53 ? 9.528 51.344 -4.070 0.50 20.32 ? 53 SER A CB 1 ATOM 190 O OG A SER A 1 53 ? 9.101 50.231 -4.847 0.50 19.47 ? 53 SER A OG 1 ATOM 191 O OG B SER A 1 53 ? 9.639 51.582 -2.672 0.50 26.25 ? 53 SER A OG 1 ATOM 192 N N . PHE A 1 54 ? 12.257 53.116 -3.181 1.00 16.80 ? 54 PHE A N 1 ATOM 193 C CA . PHE A 1 54 ? 12.799 54.308 -2.520 1.00 14.28 ? 54 PHE A CA 1 ATOM 194 C C . PHE A 1 54 ? 11.765 55.083 -1.726 1.00 16.54 ? 54 PHE A C 1 ATOM 195 O O . PHE A 1 54 ? 11.848 56.311 -1.583 1.00 17.05 ? 54 PHE A O 1 ATOM 196 C CB . PHE A 1 54 ? 13.473 55.277 -3.539 1.00 15.12 ? 54 PHE A CB 1 ATOM 197 C CG . PHE A 1 54 ? 14.728 54.722 -4.209 1.00 13.35 ? 54 PHE A CG 1 ATOM 198 C CD1 . PHE A 1 54 ? 14.654 53.893 -5.321 1.00 12.98 ? 54 PHE A CD1 1 ATOM 199 C CD2 . PHE A 1 54 ? 15.972 55.070 -3.700 1.00 12.42 ? 54 PHE A CD2 1 ATOM 200 C CE1 . PHE A 1 54 ? 15.814 53.396 -5.946 1.00 13.24 ? 54 PHE A CE1 1 ATOM 201 C CE2 . PHE A 1 54 ? 17.139 54.600 -4.314 1.00 13.44 ? 54 PHE A CE2 1 ATOM 202 C CZ . PHE A 1 54 ? 17.069 53.761 -5.436 1.00 13.93 ? 54 PHE A CZ 1 ATOM 203 N N . LYS A 1 55 ? 10.745 54.396 -1.194 1.00 15.01 ? 55 LYS A N 1 ATOM 204 C CA . LYS A 1 55 ? 9.757 55.143 -0.384 1.00 17.44 ? 55 LYS A CA 1 ATOM 205 C C . LYS A 1 55 ? 10.339 55.593 0.936 1.00 17.69 ? 55 LYS A C 1 ATOM 206 O O . LYS A 1 55 ? 11.019 54.843 1.611 1.00 19.83 ? 55 LYS A O 1 ATOM 207 C CB . LYS A 1 55 ? 8.502 54.276 -0.093 1.00 19.21 ? 55 LYS A CB 1 ATOM 208 C CG . LYS A 1 55 ? 7.777 53.845 -1.346 1.00 20.96 ? 55 LYS A CG 1 ATOM 209 C CD . LYS A 1 55 ? 7.531 55.000 -2.342 1.00 19.26 ? 55 LYS A CD 1 ATOM 210 C CE . LYS A 1 55 ? 6.643 54.528 -3.526 1.00 23.57 ? 55 LYS A CE 1 ATOM 211 N NZ . LYS A 1 55 ? 6.457 55.587 -4.588 1.00 23.18 ? 55 LYS A NZ 1 ATOM 212 N N . ASP A 1 56 ? 10.080 56.825 1.320 1.00 15.89 ? 56 ASP A N 1 ATOM 213 C CA . ASP A 1 56 ? 10.588 57.412 2.519 1.00 15.26 ? 56 ASP A CA 1 ATOM 214 C C . ASP A 1 56 ? 9.516 57.367 3.627 1.00 18.29 ? 56 ASP A C 1 ATOM 215 O O . ASP A 1 56 ? 8.926 58.390 3.987 1.00 20.44 ? 56 ASP A O 1 ATOM 216 C CB . ASP A 1 56 ? 11.031 58.851 2.201 1.00 16.45 ? 56 ASP A CB 1 ATOM 217 C CG . ASP A 1 56 ? 11.728 59.521 3.363 1.00 16.78 ? 56 ASP A CG 1 ATOM 218 O OD1 . ASP A 1 56 ? 12.221 58.829 4.288 1.00 16.69 ? 56 ASP A OD1 1 ATOM 219 O OD2 . ASP A 1 56 ? 11.787 60.767 3.398 1.00 20.12 ? 56 ASP A OD2 1 ATOM 220 N N . ILE A 1 57 ? 9.314 56.201 4.197 1.00 19.19 ? 57 ILE A N 1 ATOM 221 C CA . ILE A 1 57 ? 8.298 56.115 5.225 1.00 22.02 ? 57 ILE A CA 1 ATOM 222 C C . ILE A 1 57 ? 8.890 56.120 6.598 1.00 20.83 ? 57 ILE A C 1 ATOM 223 O O . ILE A 1 57 ? 10.042 55.764 6.819 1.00 21.50 ? 57 ILE A O 1 ATOM 224 C CB . ILE A 1 57 ? 7.315 54.899 4.994 1.00 28.87 ? 57 ILE A CB 1 ATOM 225 C CG1 . ILE A 1 57 ? 7.712 53.711 5.818 1.00 29.88 ? 57 ILE A CG1 1 ATOM 226 C CG2 . ILE A 1 57 ? 7.177 54.549 3.519 1.00 31.05 ? 57 ILE A CG2 1 ATOM 227 C CD1 . ILE A 1 57 ? 6.978 53.722 7.109 1.00 36.02 ? 57 ILE A CD1 1 ATOM 228 N N . ASP A 1 58 ? 8.093 56.561 7.557 1.00 21.44 ? 58 ASP A N 1 ATOM 229 C CA . ASP A 1 58 ? 8.504 56.649 8.941 1.00 19.82 ? 58 ASP A CA 1 ATOM 230 C C . ASP A 1 58 ? 8.532 55.241 9.518 1.00 20.69 ? 58 ASP A C 1 ATOM 231 O O . ASP A 1 58 ? 7.490 54.605 9.686 1.00 21.98 ? 58 ASP A O 1 ATOM 232 C CB . ASP A 1 58 ? 7.505 57.519 9.685 1.00 20.47 ? 58 ASP A CB 1 ATOM 233 C CG . ASP A 1 58 ? 7.889 57.781 11.109 1.00 25.77 ? 58 ASP A CG 1 ATOM 234 O OD1 . ASP A 1 58 ? 7.317 58.735 11.692 1.00 31.45 ? 58 ASP A OD1 1 ATOM 235 O OD2 . ASP A 1 58 ? 8.741 57.073 11.692 1.00 22.84 ? 58 ASP A OD2 1 ATOM 236 N N . GLY A 1 59 ? 9.730 54.729 9.788 1.00 17.31 ? 59 GLY A N 1 ATOM 237 C CA . GLY A 1 59 ? 9.841 53.393 10.314 1.00 16.82 ? 59 GLY A CA 1 ATOM 238 C C . GLY A 1 59 ? 9.750 53.287 11.826 1.00 14.48 ? 59 GLY A C 1 ATOM 239 O O . GLY A 1 59 ? 9.973 52.186 12.316 1.00 16.84 ? 59 GLY A O 1 ATOM 240 N N . GLY A 1 60 ? 9.493 54.380 12.516 1.00 15.81 ? 60 GLY A N 1 ATOM 241 C CA . GLY A 1 60 ? 9.425 54.305 13.964 1.00 17.41 ? 60 GLY A CA 1 ATOM 242 C C . GLY A 1 60 ? 10.694 54.931 14.566 1.00 16.47 ? 60 GLY A C 1 ATOM 243 O O . GLY A 1 60 ? 11.208 55.924 14.021 1.00 18.26 ? 60 GLY A O 1 ATOM 244 N N . VAL A 1 61 ? 11.192 54.405 15.687 1.00 15.47 ? 61 VAL A N 1 ATOM 245 C CA . VAL A 1 61 ? 12.376 54.998 16.304 1.00 15.11 ? 61 VAL A CA 1 ATOM 246 C C . VAL A 1 61 ? 13.552 54.888 15.296 1.00 13.16 ? 61 VAL A C 1 ATOM 247 O O . VAL A 1 61 ? 14.389 55.826 15.265 1.00 14.98 ? 61 VAL A O 1 ATOM 248 C CB . VAL A 1 61 ? 12.754 54.386 17.665 1.00 14.76 ? 61 VAL A CB 1 ATOM 249 C CG1 . VAL A 1 61 ? 11.650 54.766 18.712 1.00 18.47 ? 61 VAL A CG1 1 ATOM 250 C CG2 . VAL A 1 61 ? 12.967 52.876 17.595 1.00 15.73 ? 61 VAL A CG2 1 ATOM 251 N N . TRP A 1 62 ? 13.630 53.817 14.533 1.00 13.20 ? 62 TRP A N 1 ATOM 252 C CA . TRP A 1 62 ? 14.641 53.735 13.452 1.00 11.55 ? 62 TRP A CA 1 ATOM 253 C C . TRP A 1 62 ? 13.831 54.404 12.338 1.00 14.36 ? 62 TRP A C 1 ATOM 254 O O . TRP A 1 62 ? 13.052 53.754 11.612 1.00 13.46 ? 62 TRP A O 1 ATOM 255 C CB . TRP A 1 62 ? 14.984 52.290 13.125 1.00 12.09 ? 62 TRP A CB 1 ATOM 256 C CG . TRP A 1 62 ? 15.999 52.186 12.011 1.00 9.78 ? 62 TRP A CG 1 ATOM 257 C CD1 . TRP A 1 62 ? 16.672 53.248 11.393 1.00 10.82 ? 62 TRP A CD1 1 ATOM 258 C CD2 . TRP A 1 62 ? 16.372 51.011 11.324 1.00 10.75 ? 62 TRP A CD2 1 ATOM 259 N NE1 . TRP A 1 62 ? 17.411 52.752 10.362 1.00 10.43 ? 62 TRP A NE1 1 ATOM 260 C CE2 . TRP A 1 62 ? 17.269 51.399 10.277 1.00 11.61 ? 62 TRP A CE2 1 ATOM 261 C CE3 . TRP A 1 62 ? 16.025 49.653 11.458 1.00 10.39 ? 62 TRP A CE3 1 ATOM 262 C CZ2 . TRP A 1 62 ? 17.829 50.495 9.368 1.00 11.56 ? 62 TRP A CZ2 1 ATOM 263 C CZ3 . TRP A 1 62 ? 16.575 48.731 10.550 1.00 11.58 ? 62 TRP A CZ3 1 ATOM 264 C CH2 . TRP A 1 62 ? 17.472 49.150 9.511 1.00 12.27 ? 62 TRP A CH2 1 ATOM 265 N N . LYS A 1 63 ? 14.052 55.704 12.145 1.00 13.43 ? 63 LYS A N 1 ATOM 266 C CA . LYS A 1 63 ? 13.182 56.452 11.225 1.00 13.66 ? 63 LYS A CA 1 ATOM 267 C C . LYS A 1 63 ? 13.185 55.990 9.810 1.00 15.31 ? 63 LYS A C 1 ATOM 268 O O . LYS A 1 63 ? 12.185 56.112 9.120 1.00 15.73 ? 63 LYS A O 1 ATOM 269 C CB . LYS A 1 63 ? 13.529 57.946 11.273 1.00 14.63 ? 63 LYS A CB 1 ATOM 270 C CG . LYS A 1 63 ? 13.197 58.666 12.628 1.00 22.16 ? 63 LYS A CG 1 ATOM 271 C CD . LYS A 1 63 ? 11.672 58.964 12.792 1.00 26.85 ? 63 LYS A CD 1 ATOM 272 C CE . LYS A 1 63 ? 11.267 59.617 14.153 1.00 32.90 ? 63 LYS A CE 1 ATOM 273 N NZ . LYS A 1 63 ? 11.388 58.907 15.539 1.00 32.55 ? 63 LYS A NZ 1 ATOM 274 N N . GLN A 1 64 ? 14.316 55.456 9.332 1.00 13.25 ? 64 GLN A N 1 ATOM 275 C CA . GLN A 1 64 ? 14.389 55.013 7.961 1.00 12.73 ? 64 GLN A CA 1 ATOM 276 C C . GLN A 1 64 ? 14.472 53.500 7.811 1.00 12.16 ? 64 GLN A C 1 ATOM 277 O O . GLN A 1 64 ? 14.805 52.984 6.731 1.00 11.74 ? 64 GLN A O 1 ATOM 278 C CB . GLN A 1 64 ? 15.596 55.694 7.282 1.00 12.95 ? 64 GLN A CB 1 ATOM 279 C CG . GLN A 1 64 ? 15.484 57.217 7.318 1.00 12.43 ? 64 GLN A CG 1 ATOM 280 C CD . GLN A 1 64 ? 16.862 57.886 7.163 1.00 12.07 ? 64 GLN A CD 1 ATOM 281 O OE1 . GLN A 1 64 ? 17.826 57.524 7.881 1.00 12.95 ? 64 GLN A OE1 1 ATOM 282 N NE2 . GLN A 1 64 ? 16.949 58.848 6.243 1.00 12.09 ? 64 GLN A NE2 1 ATOM 283 N N . GLY A 1 65 ? 14.076 52.797 8.897 1.00 13.08 ? 65 GLY A N 1 ATOM 284 C CA . GLY A 1 65 ? 14.056 51.326 8.878 1.00 13.69 ? 65 GLY A CA 1 ATOM 285 C C . GLY A 1 65 ? 12.684 50.765 9.288 1.00 14.42 ? 65 GLY A C 1 ATOM 286 O O . GLY A 1 65 ? 11.665 51.172 8.682 1.00 14.31 ? 65 GLY A O 1 ATOM 287 N N . TRP A 1 66 ? 12.684 49.872 10.273 1.00 15.36 ? 66 TRP A N 1 ATOM 288 C CA . TRP A 1 66 ? 11.410 49.253 10.771 1.00 14.43 ? 66 TRP A CA 1 ATOM 289 C C . TRP A 1 66 ? 11.706 48.896 12.202 1.00 14.80 ? 66 TRP A C 1 ATOM 290 O O . TRP A 1 66 ? 12.829 49.056 12.694 1.00 14.17 ? 66 TRP A O 1 ATOM 291 C CB . TRP A 1 66 ? 11.043 48.018 9.920 1.00 13.48 ? 66 TRP A CB 1 ATOM 292 C CG . TRP A 1 66 ? 12.021 46.885 10.103 1.00 13.97 ? 66 TRP A CG 1 ATOM 293 C CD1 . TRP A 1 66 ? 11.912 45.841 10.972 1.00 13.40 ? 66 TRP A CD1 1 ATOM 294 C CD2 . TRP A 1 66 ? 13.247 46.662 9.390 1.00 13.14 ? 66 TRP A CD2 1 ATOM 295 N NE1 . TRP A 1 66 ? 12.972 44.978 10.857 1.00 14.97 ? 66 TRP A NE1 1 ATOM 296 C CE2 . TRP A 1 66 ? 13.817 45.462 9.881 1.00 13.14 ? 66 TRP A CE2 1 ATOM 297 C CE3 . TRP A 1 66 ? 13.926 47.367 8.354 1.00 14.06 ? 66 TRP A CE3 1 ATOM 298 C CZ2 . TRP A 1 66 ? 15.034 44.933 9.398 1.00 15.55 ? 66 TRP A CZ2 1 ATOM 299 C CZ3 . TRP A 1 66 ? 15.132 46.834 7.877 1.00 14.25 ? 66 TRP A CZ3 1 ATOM 300 C CH2 . TRP A 1 66 ? 15.673 45.647 8.394 1.00 13.30 ? 66 TRP A CH2 1 ATOM 301 N N . ASN A 1 67 ? 10.680 48.468 12.964 1.00 15.67 ? 67 ASN A N 1 ATOM 302 C CA . ASN A 1 67 ? 10.874 48.062 14.373 1.00 14.12 ? 67 ASN A CA 1 ATOM 303 C C . ASN A 1 67 ? 11.471 46.655 14.384 1.00 14.83 ? 67 ASN A C 1 ATOM 304 O O . ASN A 1 67 ? 10.790 45.625 14.083 1.00 15.58 ? 67 ASN A O 1 ATOM 305 C CB . ASN A 1 67 ? 9.516 47.990 15.120 1.00 18.11 ? 67 ASN A CB 1 ATOM 306 C CG . ASN A 1 67 ? 8.889 49.327 15.331 1.00 21.91 ? 67 ASN A CG 1 ATOM 307 O OD1 . ASN A 1 67 ? 9.547 50.366 15.382 1.00 22.16 ? 67 ASN A OD1 1 ATOM 308 N ND2 . ASN A 1 67 ? 7.570 49.323 15.510 1.00 25.81 ? 67 ASN A ND2 1 ATOM 309 N N . ILE A 1 68 ? 12.756 46.567 14.716 1.00 13.62 ? 68 ILE A N 1 ATOM 310 C CA . ILE A 1 68 ? 13.430 45.298 14.668 1.00 14.47 ? 68 ILE A CA 1 ATOM 311 C C . ILE A 1 68 ? 12.962 44.390 15.808 1.00 14.21 ? 68 ILE A C 1 ATOM 312 O O . ILE A 1 68 ? 12.900 44.834 16.953 1.00 16.47 ? 68 ILE A O 1 ATOM 313 C CB . ILE A 1 68 ? 15.019 45.492 14.762 1.00 14.15 ? 68 ILE A CB 1 ATOM 314 C CG1 . ILE A 1 68 ? 15.537 46.301 13.551 1.00 14.25 ? 68 ILE A CG1 1 ATOM 315 C CG2 . ILE A 1 68 ? 15.725 44.142 14.822 1.00 16.52 ? 68 ILE A CG2 1 ATOM 316 C CD1 . ILE A 1 68 ? 16.956 46.861 13.789 1.00 12.73 ? 68 ILE A CD1 1 ATOM 317 N N . LYS A 1 69 ? 12.744 43.121 15.454 1.00 16.61 ? 69 LYS A N 1 ATOM 318 C CA . LYS A 1 69 ? 12.347 42.115 16.467 1.00 17.10 ? 69 LYS A CA 1 ATOM 319 C C . LYS A 1 69 ? 13.400 41.028 16.472 1.00 18.52 ? 69 LYS A C 1 ATOM 320 O O . LYS A 1 69 ? 14.035 40.766 15.455 1.00 19.02 ? 69 LYS A O 1 ATOM 321 C CB . LYS A 1 69 ? 10.987 41.518 16.091 1.00 21.06 ? 69 LYS A CB 1 ATOM 322 C CG . LYS A 1 69 ? 9.868 42.521 16.317 1.00 25.49 ? 69 LYS A CG 1 ATOM 323 C CD . LYS A 1 69 ? 8.591 41.996 15.671 1.00 35.56 ? 69 LYS A CD 1 ATOM 324 C CE . LYS A 1 69 ? 7.530 43.083 15.651 1.00 38.50 ? 69 LYS A CE 1 ATOM 325 N NZ . LYS A 1 69 ? 6.704 42.873 14.419 1.00 40.86 ? 69 LYS A NZ 1 ATOM 326 N N . TYR A 1 70 ? 13.625 40.403 17.622 1.00 18.05 ? 70 TYR A N 1 ATOM 327 C CA . TYR A 1 70 ? 14.576 39.314 17.669 1.00 16.68 ? 70 TYR A CA 1 ATOM 328 C C . TYR A 1 70 ? 14.027 38.256 18.637 1.00 18.39 ? 70 TYR A C 1 ATOM 329 O O . TYR A 1 70 ? 13.229 38.563 19.522 1.00 20.53 ? 70 TYR A O 1 ATOM 330 C CB . TYR A 1 70 ? 15.988 39.795 18.137 1.00 17.84 ? 70 TYR A CB 1 ATOM 331 C CG . TYR A 1 70 ? 16.053 40.371 19.522 1.00 15.99 ? 70 TYR A CG 1 ATOM 332 C CD1 . TYR A 1 70 ? 16.251 39.555 20.648 1.00 19.75 ? 70 TYR A CD1 1 ATOM 333 C CD2 . TYR A 1 70 ? 15.883 41.732 19.727 1.00 18.07 ? 70 TYR A CD2 1 ATOM 334 C CE1 . TYR A 1 70 ? 16.288 40.132 21.938 1.00 19.86 ? 70 TYR A CE1 1 ATOM 335 C CE2 . TYR A 1 70 ? 15.912 42.317 20.981 1.00 19.30 ? 70 TYR A CE2 1 ATOM 336 C CZ . TYR A 1 70 ? 16.110 41.513 22.104 1.00 19.17 ? 70 TYR A CZ 1 ATOM 337 O OH . TYR A 1 70 ? 16.084 42.137 23.353 1.00 21.81 ? 70 TYR A OH 1 ATOM 338 N N . ASP A 1 71 ? 14.493 37.032 18.448 1.00 20.67 ? 71 ASP A N 1 ATOM 339 C CA . ASP A 1 71 ? 14.090 35.919 19.303 1.00 21.44 ? 71 ASP A CA 1 ATOM 340 C C . ASP A 1 71 ? 15.064 35.876 20.475 1.00 23.54 ? 71 ASP A C 1 ATOM 341 O O . ASP A 1 71 ? 16.276 35.637 20.283 1.00 21.83 ? 71 ASP A O 1 ATOM 342 C CB . ASP A 1 71 ? 14.195 34.646 18.500 1.00 24.39 ? 71 ASP A CB 1 ATOM 343 C CG . ASP A 1 71 ? 13.805 33.408 19.310 1.00 29.35 ? 71 ASP A CG 1 ATOM 344 O OD1 . ASP A 1 71 ? 13.589 33.540 20.533 1.00 33.80 ? 71 ASP A OD1 1 ATOM 345 O OD2 . ASP A 1 71 ? 13.735 32.330 18.698 1.00 34.64 ? 71 ASP A OD2 1 ATOM 346 N N . PRO A 1 72 ? 14.577 36.135 21.710 1.00 25.57 ? 72 PRO A N 1 ATOM 347 C CA . PRO A 1 72 ? 15.519 36.093 22.830 1.00 26.58 ? 72 PRO A CA 1 ATOM 348 C C . PRO A 1 72 ? 16.274 34.773 22.972 1.00 25.73 ? 72 PRO A C 1 ATOM 349 O O . PRO A 1 72 ? 17.375 34.747 23.494 1.00 25.74 ? 72 PRO A O 1 ATOM 350 C CB . PRO A 1 72 ? 14.651 36.458 24.049 1.00 27.51 ? 72 PRO A CB 1 ATOM 351 C CG . PRO A 1 72 ? 13.289 36.129 23.625 1.00 30.55 ? 72 PRO A CG 1 ATOM 352 C CD . PRO A 1 72 ? 13.222 36.473 22.174 1.00 26.71 ? 72 PRO A CD 1 ATOM 353 N N . LEU A 1 73 ? 15.712 33.691 22.451 1.00 25.51 ? 73 LEU A N 1 ATOM 354 C CA . LEU A 1 73 ? 16.370 32.400 22.536 1.00 26.90 ? 73 LEU A CA 1 ATOM 355 C C . LEU A 1 73 ? 17.511 32.168 21.528 1.00 24.88 ? 73 LEU A C 1 ATOM 356 O O . LEU A 1 73 ? 18.193 31.139 21.554 1.00 26.29 ? 73 LEU A O 1 ATOM 357 C CB . LEU A 1 73 ? 15.316 31.289 22.384 1.00 27.51 ? 73 LEU A CB 1 ATOM 358 C CG . LEU A 1 73 ? 14.191 31.364 23.428 1.00 31.04 ? 73 LEU A CG 1 ATOM 359 C CD1 . LEU A 1 73 ? 13.187 30.243 23.156 1.00 32.64 ? 73 LEU A CD1 1 ATOM 360 C CD2 . LEU A 1 73 ? 14.789 31.250 24.847 1.00 32.42 ? 73 LEU A CD2 1 ATOM 361 N N . LYS A 1 74 ? 17.740 33.140 20.626 1.00 20.84 ? 74 LYS A N 1 ATOM 362 C CA . LYS A 1 74 ? 18.797 32.974 19.645 1.00 22.16 ? 74 LYS A CA 1 ATOM 363 C C . LYS A 1 74 ? 20.201 32.820 20.251 1.00 19.14 ? 74 LYS A C 1 ATOM 364 O O . LYS A 1 74 ? 21.054 32.073 19.762 1.00 22.11 ? 74 LYS A O 1 ATOM 365 C CB . LYS A 1 74 ? 18.753 34.162 18.701 1.00 22.15 ? 74 LYS A CB 1 ATOM 366 C CG . LYS A 1 74 ? 19.830 34.173 17.648 1.00 26.26 ? 74 LYS A CG 1 ATOM 367 C CD . LYS A 1 74 ? 19.463 35.314 16.683 1.00 25.15 ? 74 LYS A CD 1 ATOM 368 C CE . LYS A 1 74 ? 20.538 35.621 15.697 1.00 33.36 ? 74 LYS A CE 1 ATOM 369 N NZ . LYS A 1 74 ? 21.011 34.392 15.049 1.00 38.12 ? 74 LYS A NZ 1 ATOM 370 N N A TYR A 1 75 ? 20.441 33.554 21.323 0.50 20.98 ? 75 TYR A N 1 ATOM 371 N N B TYR A 1 75 ? 20.441 33.554 21.323 0.50 22.55 ? 75 TYR A N 1 ATOM 372 C CA A TYR A 1 75 ? 21.743 33.463 21.991 0.50 19.09 ? 75 TYR A CA 1 ATOM 373 C CA B TYR A 1 75 ? 21.743 33.463 21.991 0.50 22.35 ? 75 TYR A CA 1 ATOM 374 C C A TYR A 1 75 ? 21.525 32.682 23.318 0.50 21.11 ? 75 TYR A C 1 ATOM 375 C C B TYR A 1 75 ? 21.550 32.579 23.256 0.50 23.20 ? 75 TYR A C 1 ATOM 376 O O A TYR A 1 75 ? 20.506 32.842 23.964 0.50 23.18 ? 75 TYR A O 1 ATOM 377 O O B TYR A 1 75 ? 20.523 32.652 23.905 0.50 25.74 ? 75 TYR A O 1 ATOM 378 C CB A TYR A 1 75 ? 22.298 34.887 22.218 0.50 20.18 ? 75 TYR A CB 1 ATOM 379 C CB B TYR A 1 75 ? 22.243 34.886 22.326 0.50 26.01 ? 75 TYR A CB 1 ATOM 380 C CG A TYR A 1 75 ? 22.678 35.540 20.902 0.50 13.19 ? 75 TYR A CG 1 ATOM 381 C CG B TYR A 1 75 ? 21.997 35.836 21.168 0.50 27.14 ? 75 TYR A CG 1 ATOM 382 C CD1 A TYR A 1 75 ? 21.911 36.555 20.339 0.50 18.70 ? 75 TYR A CD1 1 ATOM 383 C CD1 B TYR A 1 75 ? 20.949 36.752 21.182 0.50 28.84 ? 75 TYR A CD1 1 ATOM 384 C CD2 A TYR A 1 75 ? 23.736 35.045 20.173 0.50 12.79 ? 75 TYR A CD2 1 ATOM 385 C CD2 B TYR A 1 75 ? 22.743 35.720 20.017 0.50 28.72 ? 75 TYR A CD2 1 ATOM 386 C CE1 A TYR A 1 75 ? 22.204 37.031 19.076 0.50 16.28 ? 75 TYR A CE1 1 ATOM 387 C CE1 B TYR A 1 75 ? 20.667 37.504 20.058 0.50 27.93 ? 75 TYR A CE1 1 ATOM 388 C CE2 A TYR A 1 75 ? 24.048 35.509 18.870 0.50 18.16 ? 75 TYR A CE2 1 ATOM 389 C CE2 B TYR A 1 75 ? 22.464 36.472 18.848 0.50 31.44 ? 75 TYR A CE2 1 ATOM 390 C CZ A TYR A 1 75 ? 23.281 36.494 18.318 0.50 15.89 ? 75 TYR A CZ 1 ATOM 391 C CZ B TYR A 1 75 ? 21.424 37.357 18.864 0.50 31.65 ? 75 TYR A CZ 1 ATOM 392 O OH A TYR A 1 75 ? 23.569 36.902 16.964 0.50 17.61 ? 75 TYR A OH 1 ATOM 393 O OH B TYR A 1 75 ? 21.111 38.059 17.643 0.50 35.12 ? 75 TYR A OH 1 ATOM 394 N N . ASN A 1 76 ? 22.493 31.854 23.671 1.00 21.00 ? 76 ASN A N 1 ATOM 395 C CA . ASN A 1 76 ? 22.428 30.992 24.863 1.00 22.25 ? 76 ASN A CA 1 ATOM 396 C C . ASN A 1 76 ? 23.856 30.656 25.283 1.00 22.04 ? 76 ASN A C 1 ATOM 397 O O . ASN A 1 76 ? 24.839 31.095 24.671 1.00 24.58 ? 76 ASN A O 1 ATOM 398 C CB . ASN A 1 76 ? 21.633 29.699 24.556 1.00 24.44 ? 76 ASN A CB 1 ATOM 399 C CG . ASN A 1 76 ? 22.186 28.920 23.385 1.00 23.07 ? 76 ASN A CG 1 ATOM 400 O OD1 . ASN A 1 76 ? 23.385 28.706 23.265 1.00 27.48 ? 76 ASN A OD1 1 ATOM 401 N ND2 . ASN A 1 76 ? 21.285 28.465 22.505 1.00 32.38 ? 76 ASN A ND2 1 ATOM 402 N N . ALA A 1 77 ? 24.003 29.875 26.362 1.00 26.24 ? 77 ALA A N 1 ATOM 403 C CA . ALA A 1 77 ? 25.361 29.581 26.831 1.00 26.14 ? 77 ALA A CA 1 ATOM 404 C C . ALA A 1 77 ? 26.315 29.017 25.785 1.00 27.43 ? 77 ALA A C 1 ATOM 405 O O . ALA A 1 77 ? 27.533 29.226 25.850 1.00 29.01 ? 77 ALA A O 1 ATOM 406 C CB . ALA A 1 77 ? 25.302 28.635 28.027 1.00 31.22 ? 77 ALA A CB 1 ATOM 407 N N . HIS A 1 78 ? 25.790 28.322 24.795 1.00 31.20 ? 78 HIS A N 1 ATOM 408 C CA . HIS A 1 78 ? 26.710 27.755 23.812 1.00 32.56 ? 78 HIS A CA 1 ATOM 409 C C . HIS A 1 78 ? 26.834 28.580 22.540 1.00 31.40 ? 78 HIS A C 1 ATOM 410 O O . HIS A 1 78 ? 27.536 28.188 21.610 1.00 32.65 ? 78 HIS A O 1 ATOM 411 C CB . HIS A 1 78 ? 26.296 26.300 23.509 1.00 36.39 ? 78 HIS A CB 1 ATOM 412 C CG . HIS A 1 78 ? 26.070 25.490 24.750 1.00 41.39 ? 78 HIS A CG 1 ATOM 413 N ND1 . HIS A 1 78 ? 27.034 25.350 25.732 1.00 43.75 ? 78 HIS A ND1 1 ATOM 414 C CD2 . HIS A 1 78 ? 24.956 24.881 25.227 1.00 43.09 ? 78 HIS A CD2 1 ATOM 415 C CE1 . HIS A 1 78 ? 26.521 24.697 26.762 1.00 45.86 ? 78 HIS A CE1 1 ATOM 416 N NE2 . HIS A 1 78 ? 25.261 24.402 26.483 1.00 47.37 ? 78 HIS A NE2 1 ATOM 417 N N . HIS A 1 79 ? 26.188 29.747 22.543 1.00 27.01 ? 79 HIS A N 1 ATOM 418 C CA . HIS A 1 79 ? 26.193 30.635 21.372 1.00 22.58 ? 79 HIS A CA 1 ATOM 419 C C . HIS A 1 79 ? 25.944 32.062 21.858 1.00 15.70 ? 79 HIS A C 1 ATOM 420 O O . HIS A 1 79 ? 24.810 32.528 21.879 1.00 19.08 ? 79 HIS A O 1 ATOM 421 C CB . HIS A 1 79 ? 25.071 30.241 20.438 1.00 22.99 ? 79 HIS A CB 1 ATOM 422 C CG . HIS A 1 79 ? 25.166 30.902 19.092 1.00 22.77 ? 79 HIS A CG 1 ATOM 423 N ND1 . HIS A 1 79 ? 24.260 31.846 18.649 1.00 26.50 ? 79 HIS A ND1 1 ATOM 424 C CD2 . HIS A 1 79 ? 26.116 30.812 18.129 1.00 24.13 ? 79 HIS A CD2 1 ATOM 425 C CE1 . HIS A 1 79 ? 24.655 32.318 17.477 1.00 21.62 ? 79 HIS A CE1 1 ATOM 426 N NE2 . HIS A 1 79 ? 25.777 31.708 17.141 1.00 23.83 ? 79 HIS A NE2 1 ATOM 427 N N . LYS A 1 80 ? 27.023 32.702 22.291 1.00 15.77 ? 80 LYS A N 1 ATOM 428 C CA . LYS A 1 80 ? 26.874 34.026 22.850 1.00 15.58 ? 80 LYS A CA 1 ATOM 429 C C . LYS A 1 80 ? 27.079 35.113 21.768 1.00 15.28 ? 80 LYS A C 1 ATOM 430 O O . LYS A 1 80 ? 27.687 34.845 20.718 1.00 17.84 ? 80 LYS A O 1 ATOM 431 C CB . LYS A 1 80 ? 27.921 34.259 23.908 1.00 16.23 ? 80 LYS A CB 1 ATOM 432 C CG . LYS A 1 80 ? 27.845 33.201 25.044 1.00 18.85 ? 80 LYS A CG 1 ATOM 433 C CD . LYS A 1 80 ? 29.053 33.266 25.939 1.00 27.28 ? 80 LYS A CD 1 ATOM 434 C CE . LYS A 1 80 ? 29.025 34.483 26.820 1.00 28.29 ? 80 LYS A CE 1 ATOM 435 N NZ . LYS A 1 80 ? 29.917 34.252 28.048 1.00 31.25 ? 80 LYS A NZ 1 ATOM 436 N N . LEU A 1 81 ? 26.550 36.282 22.027 1.00 13.46 ? 81 LEU A N 1 ATOM 437 C CA . LEU A 1 81 ? 26.795 37.443 21.128 1.00 11.81 ? 81 LEU A CA 1 ATOM 438 C C . LEU A 1 81 ? 28.109 38.116 21.608 1.00 13.96 ? 81 LEU A C 1 ATOM 439 O O . LEU A 1 81 ? 28.216 38.521 22.779 1.00 13.96 ? 81 LEU A O 1 ATOM 440 C CB . LEU A 1 81 ? 25.639 38.410 21.258 1.00 12.30 ? 81 LEU A CB 1 ATOM 441 C CG . LEU A 1 81 ? 25.742 39.686 20.390 1.00 12.98 ? 81 LEU A CG 1 ATOM 442 C CD1 . LEU A 1 81 ? 25.774 39.271 18.914 1.00 13.41 ? 81 LEU A CD1 1 ATOM 443 C CD2 . LEU A 1 81 ? 24.582 40.640 20.719 1.00 16.15 ? 81 LEU A CD2 1 ATOM 444 N N A LYS A 1 82 ? 29.117 38.200 20.760 0.50 11.61 ? 82 LYS A N 1 ATOM 445 N N B LYS A 1 82 ? 29.109 38.154 20.772 0.50 13.05 ? 82 LYS A N 1 ATOM 446 C CA A LYS A 1 82 ? 30.372 38.824 21.133 0.50 10.31 ? 82 LYS A CA 1 ATOM 447 C CA B LYS A 1 82 ? 30.345 38.836 21.116 0.50 12.04 ? 82 LYS A CA 1 ATOM 448 C C A LYS A 1 82 ? 30.283 40.244 20.625 0.50 9.55 ? 82 LYS A C 1 ATOM 449 C C B LYS A 1 82 ? 30.318 40.278 20.630 0.50 11.57 ? 82 LYS A C 1 ATOM 450 O O A LYS A 1 82 ? 30.046 40.439 19.401 0.50 12.02 ? 82 LYS A O 1 ATOM 451 O O B LYS A 1 82 ? 29.975 40.444 19.419 0.50 13.94 ? 82 LYS A O 1 ATOM 452 C CB A LYS A 1 82 ? 31.502 38.101 20.436 0.50 11.55 ? 82 LYS A CB 1 ATOM 453 C CB B LYS A 1 82 ? 31.541 38.080 20.543 0.50 15.80 ? 82 LYS A CB 1 ATOM 454 C CG A LYS A 1 82 ? 32.883 38.677 20.633 0.50 15.46 ? 82 LYS A CG 1 ATOM 455 C CG B LYS A 1 82 ? 31.440 36.570 20.688 0.50 19.19 ? 82 LYS A CG 1 ATOM 456 C CD A LYS A 1 82 ? 33.369 38.559 22.085 0.50 23.93 ? 82 LYS A CD 1 ATOM 457 C CD B LYS A 1 82 ? 32.710 35.883 20.217 0.50 28.43 ? 82 LYS A CD 1 ATOM 458 C CE A LYS A 1 82 ? 34.878 38.204 22.068 0.50 25.56 ? 82 LYS A CE 1 ATOM 459 C CE B LYS A 1 82 ? 32.394 34.708 19.304 0.50 33.36 ? 82 LYS A CE 1 ATOM 460 N NZ A LYS A 1 82 ? 35.386 38.011 23.445 0.50 30.24 ? 82 LYS A NZ 1 ATOM 461 N NZ B LYS A 1 82 ? 32.679 33.403 19.959 0.50 33.51 ? 82 LYS A NZ 1 ATOM 462 N N . VAL A 1 83 ? 30.468 41.229 21.489 1.00 9.35 ? 83 VAL A N 1 ATOM 463 C CA . VAL A 1 83 ? 30.309 42.637 21.128 1.00 9.92 ? 83 VAL A CA 1 ATOM 464 C C . VAL A 1 83 ? 31.655 43.340 21.276 1.00 10.00 ? 83 VAL A C 1 ATOM 465 O O . VAL A 1 83 ? 32.289 43.316 22.366 1.00 11.71 ? 83 VAL A O 1 ATOM 466 C CB . VAL A 1 83 ? 29.284 43.290 22.067 1.00 9.44 ? 83 VAL A CB 1 ATOM 467 C CG1 . VAL A 1 83 ? 29.066 44.803 21.708 1.00 11.96 ? 83 VAL A CG1 1 ATOM 468 C CG2 . VAL A 1 83 ? 27.930 42.543 21.903 1.00 11.48 ? 83 VAL A CG2 1 ATOM 469 N N . PHE A 1 84 ? 32.075 44.052 20.209 1.00 10.47 ? 84 PHE A N 1 ATOM 470 C CA . PHE A 1 84 ? 33.319 44.830 20.234 1.00 10.44 ? 84 PHE A CA 1 ATOM 471 C C . PHE A 1 84 ? 32.951 46.307 20.182 1.00 9.64 ? 84 PHE A C 1 ATOM 472 O O . PHE A 1 84 ? 32.407 46.790 19.166 1.00 10.15 ? 84 PHE A O 1 ATOM 473 C CB . PHE A 1 84 ? 34.198 44.476 19.042 1.00 12.39 ? 84 PHE A CB 1 ATOM 474 C CG . PHE A 1 84 ? 34.831 43.142 19.181 1.00 11.97 ? 84 PHE A CG 1 ATOM 475 C CD1 . PHE A 1 84 ? 34.384 42.059 18.473 1.00 14.59 ? 84 PHE A CD1 1 ATOM 476 C CD2 . PHE A 1 84 ? 35.913 42.987 20.055 1.00 15.64 ? 84 PHE A CD2 1 ATOM 477 C CE1 . PHE A 1 84 ? 35.034 40.798 18.610 1.00 18.25 ? 84 PHE A CE1 1 ATOM 478 C CE2 . PHE A 1 84 ? 36.586 41.735 20.209 1.00 14.92 ? 84 PHE A CE2 1 ATOM 479 C CZ . PHE A 1 84 ? 36.142 40.653 19.468 1.00 17.64 ? 84 PHE A CZ 1 ATOM 480 N N . VAL A 1 85 ? 33.238 47.045 21.259 1.00 9.67 ? 85 VAL A N 1 ATOM 481 C CA . VAL A 1 85 ? 32.965 48.501 21.325 1.00 9.32 ? 85 VAL A CA 1 ATOM 482 C C . VAL A 1 85 ? 34.287 49.133 20.914 1.00 9.17 ? 85 VAL A C 1 ATOM 483 O O . VAL A 1 85 ? 35.327 48.937 21.575 1.00 9.69 ? 85 VAL A O 1 ATOM 484 C CB . VAL A 1 85 ? 32.555 48.899 22.743 1.00 8.85 ? 85 VAL A CB 1 ATOM 485 C CG1 . VAL A 1 85 ? 32.383 50.421 22.857 1.00 12.07 ? 85 VAL A CG1 1 ATOM 486 C CG2 . VAL A 1 85 ? 31.210 48.190 23.104 1.00 11.30 ? 85 VAL A CG2 1 ATOM 487 N N . VAL A 1 86 ? 34.243 49.878 19.821 1.00 8.05 ? 86 VAL A N 1 ATOM 488 C CA . VAL A 1 86 ? 35.496 50.395 19.202 1.00 8.90 ? 86 VAL A CA 1 ATOM 489 C C . VAL A 1 86 ? 35.565 51.912 19.322 1.00 8.28 ? 86 VAL A C 1 ATOM 490 O O . VAL A 1 86 ? 34.902 52.631 18.555 1.00 9.27 ? 86 VAL A O 1 ATOM 491 C CB . VAL A 1 86 ? 35.532 49.942 17.717 1.00 9.30 ? 86 VAL A CB 1 ATOM 492 C CG1 . VAL A 1 86 ? 36.836 50.496 17.030 1.00 11.70 ? 86 VAL A CG1 1 ATOM 493 C CG2 . VAL A 1 86 ? 35.501 48.377 17.604 1.00 10.70 ? 86 VAL A CG2 1 ATOM 494 N N . PRO A 1 87 ? 36.341 52.433 20.290 1.00 7.78 ? 87 PRO A N 1 ATOM 495 C CA . PRO A 1 87 ? 36.435 53.899 20.452 1.00 8.65 ? 87 PRO A CA 1 ATOM 496 C C . PRO A 1 87 ? 37.161 54.551 19.244 1.00 8.34 ? 87 PRO A C 1 ATOM 497 O O . PRO A 1 87 ? 38.185 53.989 18.742 1.00 8.19 ? 87 PRO A O 1 ATOM 498 C CB . PRO A 1 87 ? 37.278 54.064 21.738 1.00 8.08 ? 87 PRO A CB 1 ATOM 499 C CG . PRO A 1 87 ? 36.986 52.754 22.425 1.00 10.19 ? 87 PRO A CG 1 ATOM 500 C CD . PRO A 1 87 ? 37.045 51.718 21.373 1.00 9.40 ? 87 PRO A CD 1 ATOM 501 N N . HIS A 1 88 ? 36.662 55.715 18.841 1.00 7.40 ? 88 HIS A N 1 ATOM 502 C CA . HIS A 1 88 ? 37.236 56.403 17.637 1.00 8.53 ? 88 HIS A CA 1 ATOM 503 C C . HIS A 1 88 ? 36.958 57.881 17.750 1.00 9.00 ? 88 HIS A C 1 ATOM 504 O O . HIS A 1 88 ? 36.130 58.351 18.549 1.00 8.38 ? 88 HIS A O 1 ATOM 505 C CB . HIS A 1 88 ? 36.640 55.805 16.319 1.00 8.58 ? 88 HIS A CB 1 ATOM 506 C CG . HIS A 1 88 ? 35.189 56.107 16.122 1.00 8.35 ? 88 HIS A CG 1 ATOM 507 N ND1 . HIS A 1 88 ? 34.750 57.165 15.344 1.00 8.94 ? 88 HIS A ND1 1 ATOM 508 C CD2 . HIS A 1 88 ? 34.077 55.472 16.587 1.00 8.14 ? 88 HIS A CD2 1 ATOM 509 C CE1 . HIS A 1 88 ? 33.427 57.158 15.330 1.00 9.49 ? 88 HIS A CE1 1 ATOM 510 N NE2 . HIS A 1 88 ? 32.987 56.142 16.084 1.00 10.00 ? 88 HIS A NE2 1 ATOM 511 N N . SER A 1 89 ? 37.640 58.670 16.916 1.00 8.61 ? 89 SER A N 1 ATOM 512 C CA . SER A 1 89 ? 37.518 60.109 16.900 1.00 8.98 ? 89 SER A CA 1 ATOM 513 C C . SER A 1 89 ? 37.673 60.555 15.419 1.00 8.33 ? 89 SER A C 1 ATOM 514 O O . SER A 1 89 ? 38.782 60.355 14.851 1.00 9.25 ? 89 SER A O 1 ATOM 515 C CB . SER A 1 89 ? 38.648 60.666 17.780 1.00 9.23 ? 89 SER A CB 1 ATOM 516 O OG . SER A 1 89 ? 38.609 62.095 17.730 1.00 9.73 ? 89 SER A OG 1 ATOM 517 N N . HIS A 1 90 ? 36.659 61.184 14.892 1.00 8.42 ? 90 HIS A N 1 ATOM 518 C CA . HIS A 1 90 ? 36.731 61.597 13.477 1.00 7.93 ? 90 HIS A CA 1 ATOM 519 C C . HIS A 1 90 ? 37.381 62.977 13.397 1.00 8.60 ? 90 HIS A C 1 ATOM 520 O O . HIS A 1 90 ? 36.849 63.971 13.857 1.00 10.01 ? 90 HIS A O 1 ATOM 521 C CB . HIS A 1 90 ? 35.336 61.575 12.866 1.00 9.10 ? 90 HIS A CB 1 ATOM 522 C CG . HIS A 1 90 ? 35.327 61.942 11.407 1.00 8.75 ? 90 HIS A CG 1 ATOM 523 N ND1 . HIS A 1 90 ? 35.856 61.129 10.428 1.00 10.65 ? 90 HIS A ND1 1 ATOM 524 C CD2 . HIS A 1 90 ? 34.908 63.058 10.795 1.00 10.03 ? 90 HIS A CD2 1 ATOM 525 C CE1 . HIS A 1 90 ? 35.765 61.772 9.257 1.00 8.30 ? 90 HIS A CE1 1 ATOM 526 N NE2 . HIS A 1 90 ? 35.215 62.945 9.444 1.00 9.75 ? 90 HIS A NE2 1 ATOM 527 N N . ASN A 1 91 ? 38.569 62.989 12.811 1.00 9.25 ? 91 ASN A N 1 ATOM 528 C CA . ASN A 1 91 ? 39.384 64.207 12.722 1.00 9.02 ? 91 ASN A CA 1 ATOM 529 C C . ASN A 1 91 ? 39.552 64.674 11.279 1.00 9.82 ? 91 ASN A C 1 ATOM 530 O O . ASN A 1 91 ? 40.198 63.976 10.466 1.00 15.69 ? 91 ASN A O 1 ATOM 531 C CB . ASN A 1 91 ? 40.788 63.959 13.315 1.00 10.28 ? 91 ASN A CB 1 ATOM 532 C CG . ASN A 1 91 ? 40.755 63.874 14.828 1.00 9.62 ? 91 ASN A CG 1 ATOM 533 O OD1 . ASN A 1 91 ? 40.149 62.945 15.385 1.00 12.28 ? 91 ASN A OD1 1 ATOM 534 N ND2 . ASN A 1 91 ? 41.375 64.781 15.494 1.00 7.67 ? 91 ASN A ND2 1 ATOM 535 N N . ASP A 1 92 ? 38.989 65.796 10.942 1.00 8.62 ? 92 ASP A N 1 ATOM 536 C CA . ASP A 1 92 ? 39.114 66.306 9.563 1.00 10.24 ? 92 ASP A CA 1 ATOM 537 C C . ASP A 1 92 ? 40.349 67.134 9.374 1.00 9.75 ? 92 ASP A C 1 ATOM 538 O O . ASP A 1 92 ? 40.554 68.096 10.111 1.00 10.70 ? 92 ASP A O 1 ATOM 539 C CB . ASP A 1 92 ? 37.943 67.250 9.307 1.00 11.49 ? 92 ASP A CB 1 ATOM 540 C CG . ASP A 1 92 ? 36.708 66.526 9.199 1.00 13.97 ? 92 ASP A CG 1 ATOM 541 O OD1 . ASP A 1 92 ? 36.692 65.603 8.430 1.00 13.04 ? 92 ASP A OD1 1 ATOM 542 O OD2 . ASP A 1 92 ? 35.723 66.841 9.909 1.00 16.72 ? 92 ASP A OD2 1 ATOM 543 N N . PRO A 1 93 ? 41.188 66.825 8.354 1.00 9.45 ? 93 PRO A N 1 ATOM 544 C CA . PRO A 1 93 ? 42.406 67.624 8.070 1.00 9.35 ? 93 PRO A CA 1 ATOM 545 C C . PRO A 1 93 ? 41.977 68.892 7.285 1.00 10.86 ? 93 PRO A C 1 ATOM 546 O O . PRO A 1 93 ? 42.308 69.061 6.089 1.00 12.61 ? 93 PRO A O 1 ATOM 547 C CB . PRO A 1 93 ? 43.265 66.689 7.225 1.00 10.58 ? 93 PRO A CB 1 ATOM 548 C CG . PRO A 1 93 ? 42.712 65.296 7.489 1.00 16.38 ? 93 PRO A CG 1 ATOM 549 C CD . PRO A 1 93 ? 41.186 65.509 7.650 1.00 8.56 ? 93 PRO A CD 1 ATOM 550 N N . GLY A 1 94 ? 41.166 69.719 7.965 1.00 9.48 ? 94 GLY A N 1 ATOM 551 C CA . GLY A 1 94 ? 40.589 70.950 7.403 1.00 9.38 ? 94 GLY A CA 1 ATOM 552 C C . GLY A 1 94 ? 39.107 70.734 7.148 1.00 9.82 ? 94 GLY A C 1 ATOM 553 O O . GLY A 1 94 ? 38.701 69.673 6.610 1.00 11.11 ? 94 GLY A O 1 ATOM 554 N N . TRP A 1 95 ? 38.273 71.701 7.563 1.00 9.94 ? 95 TRP A N 1 ATOM 555 C CA . TRP A 1 95 ? 36.840 71.702 7.251 1.00 8.50 ? 95 TRP A CA 1 ATOM 556 C C . TRP A 1 95 ? 36.361 73.119 7.669 1.00 10.11 ? 95 TRP A C 1 ATOM 557 O O . TRP A 1 95 ? 36.318 74.043 6.858 1.00 9.97 ? 95 TRP A O 1 ATOM 558 C CB . TRP A 1 95 ? 36.058 70.577 7.939 1.00 8.97 ? 95 TRP A CB 1 ATOM 559 C CG . TRP A 1 95 ? 34.609 70.668 7.609 1.00 10.06 ? 95 TRP A CG 1 ATOM 560 C CD1 . TRP A 1 95 ? 34.036 71.122 6.448 1.00 9.87 ? 95 TRP A CD1 1 ATOM 561 C CD2 . TRP A 1 95 ? 33.551 70.236 8.459 1.00 12.46 ? 95 TRP A CD2 1 ATOM 562 N NE1 . TRP A 1 95 ? 32.656 71.034 6.538 1.00 11.09 ? 95 TRP A NE1 1 ATOM 563 C CE2 . TRP A 1 95 ? 32.345 70.462 7.752 1.00 11.73 ? 95 TRP A CE2 1 ATOM 564 C CE3 . TRP A 1 95 ? 33.510 69.631 9.755 1.00 15.13 ? 95 TRP A CE3 1 ATOM 565 C CZ2 . TRP A 1 95 ? 31.085 70.103 8.283 1.00 14.24 ? 95 TRP A CZ2 1 ATOM 566 C CZ3 . TRP A 1 95 ? 32.220 69.267 10.287 1.00 17.26 ? 95 TRP A CZ3 1 ATOM 567 C CH2 . TRP A 1 95 ? 31.050 69.511 9.541 1.00 18.06 ? 95 TRP A CH2 1 ATOM 568 N N . ILE A 1 96 ? 36.047 73.290 8.957 1.00 9.55 ? 96 ILE A N 1 ATOM 569 C CA . ILE A 1 96 ? 35.595 74.576 9.536 1.00 11.45 ? 96 ILE A CA 1 ATOM 570 C C . ILE A 1 96 ? 36.854 75.354 9.949 1.00 11.29 ? 96 ILE A C 1 ATOM 571 O O . ILE A 1 96 ? 36.812 76.598 10.007 1.00 13.71 ? 96 ILE A O 1 ATOM 572 C CB . ILE A 1 96 ? 34.726 74.336 10.850 1.00 16.25 ? 96 ILE A CB 1 ATOM 573 C CG1 . ILE A 1 96 ? 33.505 73.483 10.552 1.00 18.60 ? 96 ILE A CG1 1 ATOM 574 C CG2 . ILE A 1 96 ? 34.365 75.689 11.509 1.00 18.92 ? 96 ILE A CG2 1 ATOM 575 C CD1 . ILE A 1 96 ? 32.928 73.849 9.179 1.00 18.05 ? 96 ILE A CD1 1 ATOM 576 N N . GLN A 1 97 ? 37.934 74.656 10.289 1.00 9.17 ? 97 GLN A N 1 ATOM 577 C CA . GLN A 1 97 ? 39.230 75.263 10.607 1.00 9.85 ? 97 GLN A CA 1 ATOM 578 C C . GLN A 1 97 ? 40.238 74.633 9.652 1.00 9.65 ? 97 GLN A C 1 ATOM 579 O O . GLN A 1 97 ? 39.953 73.624 8.978 1.00 9.07 ? 97 GLN A O 1 ATOM 580 C CB . GLN A 1 97 ? 39.633 74.966 12.058 1.00 11.24 ? 97 GLN A CB 1 ATOM 581 C CG . GLN A 1 97 ? 38.581 75.454 13.125 1.00 13.50 ? 97 GLN A CG 1 ATOM 582 C CD . GLN A 1 97 ? 39.067 75.193 14.542 1.00 17.82 ? 97 GLN A CD 1 ATOM 583 O OE1 . GLN A 1 97 ? 40.205 75.537 14.890 1.00 24.02 ? 97 GLN A OE1 1 ATOM 584 N NE2 . GLN A 1 97 ? 38.233 74.544 15.367 1.00 21.28 ? 97 GLN A NE2 1 ATOM 585 N N . THR A 1 98 ? 41.426 75.231 9.539 1.00 9.56 ? 98 THR A N 1 ATOM 586 C CA . THR A 1 98 ? 42.476 74.652 8.703 1.00 8.39 ? 98 THR A CA 1 ATOM 587 C C . THR A 1 98 ? 43.090 73.457 9.405 1.00 9.34 ? 98 THR A C 1 ATOM 588 O O . THR A 1 98 ? 42.869 73.225 10.615 1.00 9.83 ? 98 THR A O 1 ATOM 589 C CB . THR A 1 98 ? 43.588 75.641 8.455 1.00 9.64 ? 98 THR A CB 1 ATOM 590 O OG1 . THR A 1 98 ? 44.174 75.973 9.724 1.00 10.12 ? 98 THR A OG1 1 ATOM 591 C CG2 . THR A 1 98 ? 43.042 76.963 7.834 1.00 10.47 ? 98 THR A CG2 1 ATOM 592 N N . PHE A 1 99 ? 43.857 72.690 8.657 1.00 9.27 ? 99 PHE A N 1 ATOM 593 C CA . PHE A 1 99 ? 44.605 71.602 9.222 1.00 8.84 ? 99 PHE A CA 1 ATOM 594 C C . PHE A 1 99 ? 45.374 72.049 10.477 1.00 9.34 ? 99 PHE A C 1 ATOM 595 O O . PHE A 1 99 ? 45.320 71.406 11.562 1.00 9.62 ? 99 PHE A O 1 ATOM 596 C CB . PHE A 1 99 ? 45.610 71.038 8.192 1.00 10.11 ? 99 PHE A CB 1 ATOM 597 C CG . PHE A 1 99 ? 46.465 69.957 8.738 1.00 9.78 ? 99 PHE A CG 1 ATOM 598 C CD1 . PHE A 1 99 ? 46.080 68.617 8.601 1.00 9.99 ? 99 PHE A CD1 1 ATOM 599 C CD2 . PHE A 1 99 ? 47.687 70.253 9.373 1.00 11.24 ? 99 PHE A CD2 1 ATOM 600 C CE1 . PHE A 1 99 ? 46.893 67.608 9.094 1.00 10.03 ? 99 PHE A CE1 1 ATOM 601 C CE2 . PHE A 1 99 ? 48.505 69.261 9.887 1.00 12.72 ? 99 PHE A CE2 1 ATOM 602 C CZ . PHE A 1 99 ? 48.102 67.901 9.745 1.00 11.04 ? 99 PHE A CZ 1 ATOM 603 N N . GLU A 1 100 ? 46.135 73.116 10.358 1.00 9.34 ? 100 GLU A N 1 ATOM 604 C CA . GLU A 1 100 ? 46.951 73.548 11.482 1.00 9.78 ? 100 GLU A CA 1 ATOM 605 C C . GLU A 1 100 ? 46.138 74.081 12.637 1.00 9.68 ? 100 GLU A C 1 ATOM 606 O O . GLU A 1 100 ? 46.504 73.830 13.815 1.00 10.20 ? 100 GLU A O 1 ATOM 607 C CB . GLU A 1 100 ? 48.009 74.586 11.041 1.00 12.11 ? 100 GLU A CB 1 ATOM 608 C CG . GLU A 1 100 ? 49.015 74.962 12.156 1.00 14.00 ? 100 GLU A CG 1 ATOM 609 C CD . GLU A 1 100 ? 49.866 73.805 12.587 1.00 15.70 ? 100 GLU A CD 1 ATOM 610 O OE1 . GLU A 1 100 ? 50.006 72.785 11.855 1.00 16.75 ? 100 GLU A OE1 1 ATOM 611 O OE2 . GLU A 1 100 ? 50.509 73.951 13.681 1.00 16.99 ? 100 GLU A OE2 1 ATOM 612 N N . GLU A 1 101 ? 45.033 74.768 12.369 1.00 9.02 ? 101 GLU A N 1 ATOM 613 C CA . GLU A 1 101 ? 44.184 75.275 13.453 1.00 10.18 ? 101 GLU A CA 1 ATOM 614 C C . GLU A 1 101 ? 43.583 74.087 14.211 1.00 9.69 ? 101 GLU A C 1 ATOM 615 O O . GLU A 1 101 ? 43.578 74.057 15.473 1.00 9.90 ? 101 GLU A O 1 ATOM 616 C CB . GLU A 1 101 ? 43.054 76.122 12.881 1.00 11.37 ? 101 GLU A CB 1 ATOM 617 C CG . GLU A 1 101 ? 43.523 77.543 12.466 1.00 15.26 ? 101 GLU A CG 1 ATOM 618 C CD . GLU A 1 101 ? 42.517 78.290 11.560 1.00 18.29 ? 101 GLU A CD 1 ATOM 619 O OE1 . GLU A 1 101 ? 41.486 77.727 11.040 1.00 14.09 ? 101 GLU A OE1 1 ATOM 620 O OE2 . GLU A 1 101 ? 42.777 79.519 11.321 1.00 22.25 ? 101 GLU A OE2 1 ATOM 621 N N . TYR A 1 102 ? 43.019 73.112 13.484 1.00 9.38 ? 102 TYR A N 1 ATOM 622 C CA . TYR A 1 102 ? 42.494 71.951 14.218 1.00 9.13 ? 102 TYR A CA 1 ATOM 623 C C . TYR A 1 102 ? 43.597 71.202 14.972 1.00 8.51 ? 102 TYR A C 1 ATOM 624 O O . TYR A 1 102 ? 43.348 70.677 16.063 1.00 10.05 ? 102 TYR A O 1 ATOM 625 C CB . TYR A 1 102 ? 41.837 70.916 13.289 1.00 10.04 ? 102 TYR A CB 1 ATOM 626 C CG . TYR A 1 102 ? 40.445 71.218 12.807 1.00 10.29 ? 102 TYR A CG 1 ATOM 627 C CD1 . TYR A 1 102 ? 39.373 71.487 13.710 1.00 10.80 ? 102 TYR A CD1 1 ATOM 628 C CD2 . TYR A 1 102 ? 40.129 71.088 11.435 1.00 10.24 ? 102 TYR A CD2 1 ATOM 629 C CE1 . TYR A 1 102 ? 38.060 71.611 13.249 1.00 10.91 ? 102 TYR A CE1 1 ATOM 630 C CE2 . TYR A 1 102 ? 38.816 71.176 10.968 1.00 10.26 ? 102 TYR A CE2 1 ATOM 631 C CZ . TYR A 1 102 ? 37.786 71.439 11.870 1.00 9.81 ? 102 TYR A CZ 1 ATOM 632 O OH . TYR A 1 102 ? 36.500 71.483 11.405 1.00 11.87 ? 102 TYR A OH 1 ATOM 633 N N . TYR A 1 103 ? 44.791 71.097 14.393 1.00 9.84 ? 103 TYR A N 1 ATOM 634 C CA . TYR A 1 103 ? 45.841 70.399 15.075 1.00 10.67 ? 103 TYR A CA 1 ATOM 635 C C . TYR A 1 103 ? 46.113 71.054 16.426 1.00 10.43 ? 103 TYR A C 1 ATOM 636 O O . TYR A 1 103 ? 46.247 70.366 17.468 1.00 10.77 ? 103 TYR A O 1 ATOM 637 C CB . TYR A 1 103 ? 47.114 70.375 14.239 1.00 10.77 ? 103 TYR A CB 1 ATOM 638 C CG . TYR A 1 103 ? 48.232 69.706 14.975 1.00 11.78 ? 103 TYR A CG 1 ATOM 639 C CD1 . TYR A 1 103 ? 48.220 68.318 15.189 1.00 12.41 ? 103 TYR A CD1 1 ATOM 640 C CD2 . TYR A 1 103 ? 49.304 70.464 15.503 1.00 11.86 ? 103 TYR A CD2 1 ATOM 641 C CE1 . TYR A 1 103 ? 49.214 67.692 15.907 1.00 11.78 ? 103 TYR A CE1 1 ATOM 642 C CE2 . TYR A 1 103 ? 50.346 69.846 16.247 1.00 11.32 ? 103 TYR A CE2 1 ATOM 643 C CZ . TYR A 1 103 ? 50.278 68.459 16.448 1.00 12.32 ? 103 TYR A CZ 1 ATOM 644 O OH . TYR A 1 103 ? 51.243 67.827 17.245 1.00 15.05 ? 103 TYR A OH 1 ATOM 645 N N . GLN A 1 104 ? 46.207 72.385 16.412 1.00 10.71 ? 104 GLN A N 1 ATOM 646 C CA . GLN A 1 104 ? 46.530 73.104 17.660 1.00 10.55 ? 104 GLN A CA 1 ATOM 647 C C . GLN A 1 104 ? 45.410 73.115 18.633 1.00 13.49 ? 104 GLN A C 1 ATOM 648 O O . GLN A 1 104 ? 45.673 73.008 19.872 1.00 14.52 ? 104 GLN A O 1 ATOM 649 C CB . GLN A 1 104 ? 46.938 74.579 17.346 1.00 14.14 ? 104 GLN A CB 1 ATOM 650 C CG . GLN A 1 104 ? 48.224 74.744 16.609 1.00 12.66 ? 104 GLN A CG 1 ATOM 651 C CD . GLN A 1 104 ? 49.413 74.222 17.400 1.00 15.50 ? 104 GLN A CD 1 ATOM 652 O OE1 . GLN A 1 104 ? 49.392 74.308 18.647 1.00 16.04 ? 104 GLN A OE1 1 ATOM 653 N NE2 . GLN A 1 104 ? 50.427 73.682 16.722 1.00 14.57 ? 104 GLN A NE2 1 ATOM 654 N N . HIS A 1 105 ? 44.173 73.200 18.166 1.00 11.33 ? 105 HIS A N 1 ATOM 655 C CA . HIS A 1 105 ? 43.037 73.349 19.100 1.00 12.68 ? 105 HIS A CA 1 ATOM 656 C C . HIS A 1 105 ? 42.435 72.043 19.554 1.00 14.09 ? 105 HIS A C 1 ATOM 657 O O . HIS A 1 105 ? 41.902 71.967 20.649 1.00 15.23 ? 105 HIS A O 1 ATOM 658 C CB . HIS A 1 105 ? 41.928 74.174 18.445 1.00 14.44 ? 105 HIS A CB 1 ATOM 659 C CG . HIS A 1 105 ? 42.373 75.540 17.987 1.00 17.03 ? 105 HIS A CG 1 ATOM 660 N ND1 . HIS A 1 105 ? 41.820 76.161 16.884 1.00 22.65 ? 105 HIS A ND1 1 ATOM 661 C CD2 . HIS A 1 105 ? 43.336 76.376 18.456 1.00 23.65 ? 105 HIS A CD2 1 ATOM 662 C CE1 . HIS A 1 105 ? 42.438 77.317 16.687 1.00 22.54 ? 105 HIS A CE1 1 ATOM 663 N NE2 . HIS A 1 105 ? 43.360 77.473 17.625 1.00 23.30 ? 105 HIS A NE2 1 ATOM 664 N N . ASP A 1 106 ? 42.591 71.003 18.739 1.00 12.23 ? 106 ASP A N 1 ATOM 665 C CA . ASP A 1 106 ? 41.924 69.750 19.010 1.00 12.39 ? 106 ASP A CA 1 ATOM 666 C C . ASP A 1 106 ? 42.761 68.519 18.888 1.00 10.42 ? 106 ASP A C 1 ATOM 667 O O . ASP A 1 106 ? 42.945 67.793 19.882 1.00 11.14 ? 106 ASP A O 1 ATOM 668 C CB . ASP A 1 106 ? 40.725 69.585 18.049 1.00 13.60 ? 106 ASP A CB 1 ATOM 669 C CG . ASP A 1 106 ? 39.652 70.660 18.280 1.00 19.13 ? 106 ASP A CG 1 ATOM 670 O OD1 . ASP A 1 106 ? 38.861 70.534 19.278 1.00 20.19 ? 106 ASP A OD1 1 ATOM 671 O OD2 . ASP A 1 106 ? 39.656 71.650 17.487 1.00 20.80 ? 106 ASP A OD2 1 ATOM 672 N N . THR A 1 107 ? 43.329 68.262 17.702 1.00 10.70 ? 107 THR A N 1 ATOM 673 C CA . THR A 1 107 ? 43.942 66.956 17.450 1.00 8.93 ? 107 THR A CA 1 ATOM 674 C C . THR A 1 107 ? 45.170 66.681 18.284 1.00 9.29 ? 107 THR A C 1 ATOM 675 O O . THR A 1 107 ? 45.372 65.528 18.727 1.00 9.25 ? 107 THR A O 1 ATOM 676 C CB . THR A 1 107 ? 44.219 66.804 15.924 1.00 8.83 ? 107 THR A CB 1 ATOM 677 O OG1 . THR A 1 107 ? 42.994 67.040 15.242 1.00 10.16 ? 107 THR A OG1 1 ATOM 678 C CG2 . THR A 1 107 ? 44.762 65.417 15.608 1.00 10.29 ? 107 THR A CG2 1 ATOM 679 N N . LYS A 1 108 ? 46.028 67.680 18.519 1.00 9.60 ? 108 LYS A N 1 ATOM 680 C CA . LYS A 1 108 ? 47.190 67.350 19.335 1.00 10.01 ? 108 LYS A CA 1 ATOM 681 C C . LYS A 1 108 ? 46.793 66.932 20.770 1.00 8.55 ? 108 LYS A C 1 ATOM 682 O O . LYS A 1 108 ? 47.480 66.111 21.343 1.00 11.06 ? 108 LYS A O 1 ATOM 683 C CB . LYS A 1 108 ? 48.168 68.539 19.326 1.00 11.86 ? 108 LYS A CB 1 ATOM 684 C CG . LYS A 1 108 ? 47.899 69.720 20.263 1.00 12.09 ? 108 LYS A CG 1 ATOM 685 C CD . LYS A 1 108 ? 49.013 70.748 20.118 1.00 13.79 ? 108 LYS A CD 1 ATOM 686 C CE . LYS A 1 108 ? 48.820 71.909 21.025 1.00 15.14 ? 108 LYS A CE 1 ATOM 687 N NZ . LYS A 1 108 ? 50.005 72.852 20.970 1.00 18.59 ? 108 LYS A NZ 1 ATOM 688 N N . HIS A 1 109 ? 45.695 67.494 21.268 1.00 9.70 ? 109 HIS A N 1 ATOM 689 C CA . HIS A 1 109 ? 45.204 67.147 22.615 1.00 10.17 ? 109 HIS A CA 1 ATOM 690 C C . HIS A 1 109 ? 44.582 65.760 22.614 1.00 9.43 ? 109 HIS A C 1 ATOM 691 O O . HIS A 1 109 ? 44.783 64.943 23.543 1.00 11.40 ? 109 HIS A O 1 ATOM 692 C CB . HIS A 1 109 ? 44.209 68.179 23.076 1.00 12.20 ? 109 HIS A CB 1 ATOM 693 C CG . HIS A 1 109 ? 44.784 69.547 23.117 1.00 13.99 ? 109 HIS A CG 1 ATOM 694 N ND1 . HIS A 1 109 ? 45.769 69.891 24.021 1.00 21.17 ? 109 HIS A ND1 1 ATOM 695 C CD2 . HIS A 1 109 ? 44.592 70.629 22.324 1.00 18.03 ? 109 HIS A CD2 1 ATOM 696 C CE1 . HIS A 1 109 ? 46.170 71.132 23.771 1.00 18.65 ? 109 HIS A CE1 1 ATOM 697 N NE2 . HIS A 1 109 ? 45.476 71.597 22.751 1.00 18.68 ? 109 HIS A NE2 1 ATOM 698 N N . ILE A 1 110 ? 43.824 65.433 21.535 1.00 9.99 ? 110 ILE A N 1 ATOM 699 C CA . ILE A 1 110 ? 43.237 64.084 21.416 1.00 9.65 ? 110 ILE A CA 1 ATOM 700 C C . ILE A 1 110 ? 44.366 63.043 21.391 1.00 8.53 ? 110 ILE A C 1 ATOM 701 O O . ILE A 1 110 ? 44.299 62.020 22.114 1.00 9.86 ? 110 ILE A O 1 ATOM 702 C CB . ILE A 1 110 ? 42.398 63.991 20.107 1.00 9.35 ? 110 ILE A CB 1 ATOM 703 C CG1 . ILE A 1 110 ? 41.215 64.935 20.230 1.00 9.51 ? 110 ILE A CG1 1 ATOM 704 C CG2 . ILE A 1 110 ? 41.976 62.529 19.816 1.00 9.55 ? 110 ILE A CG2 1 ATOM 705 C CD1 . ILE A 1 110 ? 40.449 65.171 18.882 1.00 9.66 ? 110 ILE A CD1 1 ATOM 706 N N . LEU A 1 111 ? 45.400 63.248 20.574 1.00 8.27 ? 111 LEU A N 1 ATOM 707 C CA . LEU A 1 111 ? 46.450 62.265 20.526 1.00 8.33 ? 111 LEU A CA 1 ATOM 708 C C . LEU A 1 111 ? 47.316 62.188 21.792 1.00 8.63 ? 111 LEU A C 1 ATOM 709 O O . LEU A 1 111 ? 47.704 61.112 22.214 1.00 10.11 ? 111 LEU A O 1 ATOM 710 C CB . LEU A 1 111 ? 47.344 62.505 19.263 1.00 9.37 ? 111 LEU A CB 1 ATOM 711 C CG . LEU A 1 111 ? 46.596 62.199 17.934 1.00 9.43 ? 111 LEU A CG 1 ATOM 712 C CD1 . LEU A 1 111 ? 47.425 62.676 16.727 1.00 10.17 ? 111 LEU A CD1 1 ATOM 713 C CD2 . LEU A 1 111 ? 46.364 60.710 17.858 1.00 12.81 ? 111 LEU A CD2 1 ATOM 714 N N A SER A 1 112 ? 47.572 63.345 22.374 0.50 8.26 ? 112 SER A N 1 ATOM 715 N N B SER A 1 112 ? 47.572 63.345 22.374 0.50 10.08 ? 112 SER A N 1 ATOM 716 C CA A SER A 1 112 ? 48.339 63.345 23.647 0.50 8.80 ? 112 SER A CA 1 ATOM 717 C CA B SER A 1 112 ? 48.339 63.345 23.647 0.50 12.25 ? 112 SER A CA 1 ATOM 718 C C A SER A 1 112 ? 47.559 62.612 24.760 0.50 9.62 ? 112 SER A C 1 ATOM 719 C C B SER A 1 112 ? 47.559 62.612 24.760 0.50 11.72 ? 112 SER A C 1 ATOM 720 O O A SER A 1 112 ? 48.131 61.830 25.532 0.50 10.89 ? 112 SER A O 1 ATOM 721 O O B SER A 1 112 ? 48.131 61.830 25.532 0.50 12.17 ? 112 SER A O 1 ATOM 722 C CB A SER A 1 112 ? 48.595 64.797 24.043 0.50 8.65 ? 112 SER A CB 1 ATOM 723 C CB B SER A 1 112 ? 48.595 64.797 24.043 0.50 14.85 ? 112 SER A CB 1 ATOM 724 O OG A SER A 1 112 ? 49.386 64.788 25.240 0.50 9.52 ? 112 SER A OG 1 ATOM 725 O OG B SER A 1 112 ? 49.442 65.378 23.041 0.50 19.79 ? 112 SER A OG 1 ATOM 726 N N . ASN A 1 113 ? 46.257 62.853 24.823 1.00 9.90 ? 113 ASN A N 1 ATOM 727 C CA . ASN A 1 113 ? 45.475 62.181 25.855 1.00 11.73 ? 113 ASN A CA 1 ATOM 728 C C . ASN A 1 113 ? 45.227 60.744 25.511 1.00 11.96 ? 113 ASN A C 1 ATOM 729 O O . ASN A 1 113 ? 45.154 59.909 26.437 1.00 12.34 ? 113 ASN A O 1 ATOM 730 C CB . ASN A 1 113 ? 44.220 62.997 26.168 1.00 12.63 ? 113 ASN A CB 1 ATOM 731 C CG . ASN A 1 113 ? 44.619 64.318 26.856 1.00 15.67 ? 113 ASN A CG 1 ATOM 732 O OD1 . ASN A 1 113 ? 45.713 64.408 27.450 1.00 22.97 ? 113 ASN A OD1 1 ATOM 733 N ND2 . ASN A 1 113 ? 43.833 65.333 26.724 1.00 15.61 ? 113 ASN A ND2 1 ATOM 734 N N . ALA A 1 114 ? 45.193 60.371 24.218 1.00 10.20 ? 114 ALA A N 1 ATOM 735 C CA . ALA A 1 114 ? 45.032 58.943 23.878 1.00 10.05 ? 114 ALA A CA 1 ATOM 736 C C . ALA A 1 114 ? 46.319 58.224 24.325 1.00 10.27 ? 114 ALA A C 1 ATOM 737 O O . ALA A 1 114 ? 46.249 57.114 24.885 1.00 11.74 ? 114 ALA A O 1 ATOM 738 C CB . ALA A 1 114 ? 44.871 58.774 22.361 1.00 10.86 ? 114 ALA A CB 1 ATOM 739 N N . LEU A 1 115 ? 47.482 58.830 24.103 1.00 9.70 ? 115 LEU A N 1 ATOM 740 C CA . LEU A 1 115 ? 48.711 58.176 24.516 1.00 12.27 ? 115 LEU A CA 1 ATOM 741 C C . LEU A 1 115 ? 48.723 57.957 26.056 1.00 12.61 ? 115 LEU A C 1 ATOM 742 O O . LEU A 1 115 ? 48.997 56.825 26.532 1.00 12.63 ? 115 LEU A O 1 ATOM 743 C CB . LEU A 1 115 ? 49.909 59.024 24.074 1.00 11.00 ? 115 LEU A CB 1 ATOM 744 C CG . LEU A 1 115 ? 51.291 58.503 24.522 1.00 12.08 ? 115 LEU A CG 1 ATOM 745 C CD1 . LEU A 1 115 ? 51.546 57.073 24.085 1.00 15.25 ? 115 LEU A CD1 1 ATOM 746 C CD2 . LEU A 1 115 ? 52.351 59.468 23.956 1.00 14.84 ? 115 LEU A CD2 1 ATOM 747 N N . ARG A 1 116 ? 48.360 59.006 26.789 1.00 11.74 ? 116 ARG A N 1 ATOM 748 C CA . ARG A 1 116 ? 48.338 58.869 28.251 1.00 12.56 ? 116 ARG A CA 1 ATOM 749 C C . ARG A 1 116 ? 47.285 57.823 28.723 1.00 12.39 ? 116 ARG A C 1 ATOM 750 O O . ARG A 1 116 ? 47.592 56.910 29.547 1.00 13.08 ? 116 ARG A O 1 ATOM 751 C CB . ARG A 1 116 ? 48.045 60.222 28.868 1.00 14.79 ? 116 ARG A CB 1 ATOM 752 C CG . ARG A 1 116 ? 47.803 60.193 30.388 1.00 21.45 ? 116 ARG A CG 1 ATOM 753 C CD . ARG A 1 116 ? 47.068 61.506 30.774 1.00 26.83 ? 116 ARG A CD 1 ATOM 754 N NE . ARG A 1 116 ? 46.521 61.402 32.134 1.00 31.94 ? 116 ARG A NE 1 ATOM 755 C CZ . ARG A 1 116 ? 46.051 62.425 32.846 1.00 33.41 ? 116 ARG A CZ 1 ATOM 756 N NH1 . ARG A 1 116 ? 46.040 63.662 32.336 1.00 28.19 ? 116 ARG A NH1 1 ATOM 757 N NH2 . ARG A 1 116 ? 45.635 62.199 34.093 1.00 33.03 ? 116 ARG A NH2 1 ATOM 758 N N A HIS A 1 117 ? 46.060 57.921 28.229 0.50 9.51 ? 117 HIS A N 1 ATOM 759 N N B HIS A 1 117 ? 46.060 57.921 28.229 0.50 13.78 ? 117 HIS A N 1 ATOM 760 C CA A HIS A 1 117 ? 45.029 57.023 28.701 0.50 9.54 ? 117 HIS A CA 1 ATOM 761 C CA B HIS A 1 117 ? 45.029 57.023 28.701 0.50 14.90 ? 117 HIS A CA 1 ATOM 762 C C A HIS A 1 117 ? 45.216 55.613 28.294 0.50 9.58 ? 117 HIS A C 1 ATOM 763 C C B HIS A 1 117 ? 45.315 55.590 28.466 0.50 17.04 ? 117 HIS A C 1 ATOM 764 O O A HIS A 1 117 ? 44.929 54.725 29.113 0.50 7.19 ? 117 HIS A O 1 ATOM 765 O O B HIS A 1 117 ? 44.990 54.778 29.347 0.50 20.14 ? 117 HIS A O 1 ATOM 766 C CB A HIS A 1 117 ? 43.669 57.551 28.320 0.50 9.81 ? 117 HIS A CB 1 ATOM 767 C CB B HIS A 1 117 ? 43.689 57.436 28.146 0.50 16.62 ? 117 HIS A CB 1 ATOM 768 C CG A HIS A 1 117 ? 43.245 58.696 29.191 0.50 12.07 ? 117 HIS A CG 1 ATOM 769 C CG B HIS A 1 117 ? 42.582 57.234 29.137 0.50 13.03 ? 117 HIS A CG 1 ATOM 770 N ND1 A HIS A 1 117 ? 42.559 58.495 30.380 0.50 12.22 ? 117 HIS A ND1 1 ATOM 771 N ND1 B HIS A 1 117 ? 41.827 56.070 29.162 0.50 16.26 ? 117 HIS A ND1 1 ATOM 772 C CD2 A HIS A 1 117 ? 43.527 60.020 29.123 0.50 12.56 ? 117 HIS A CD2 1 ATOM 773 C CD2 B HIS A 1 117 ? 42.201 57.969 30.210 0.50 16.45 ? 117 HIS A CD2 1 ATOM 774 C CE1 A HIS A 1 117 ? 42.458 59.662 31.014 0.50 15.70 ? 117 HIS A CE1 1 ATOM 775 C CE1 B HIS A 1 117 ? 41.036 56.100 30.233 0.50 13.03 ? 117 HIS A CE1 1 ATOM 776 N NE2 A HIS A 1 117 ? 43.039 60.600 30.278 0.50 12.98 ? 117 HIS A NE2 1 ATOM 777 N NE2 B HIS A 1 117 ? 41.246 57.235 30.887 0.50 18.47 ? 117 HIS A NE2 1 ATOM 778 N N . LEU A 1 118 ? 45.655 55.324 27.065 1.00 10.76 ? 118 LEU A N 1 ATOM 779 C CA . LEU A 1 118 ? 45.910 53.951 26.677 1.00 10.97 ? 118 LEU A CA 1 ATOM 780 C C . LEU A 1 118 ? 47.117 53.445 27.462 1.00 10.42 ? 118 LEU A C 1 ATOM 781 O O . LEU A 1 118 ? 47.095 52.272 27.909 1.00 11.95 ? 118 LEU A O 1 ATOM 782 C CB . LEU A 1 118 ? 46.180 53.858 25.122 1.00 10.52 ? 118 LEU A CB 1 ATOM 783 C CG . LEU A 1 118 ? 44.887 54.255 24.336 1.00 14.73 ? 118 LEU A CG 1 ATOM 784 C CD1 . LEU A 1 118 ? 45.331 54.325 22.834 1.00 16.14 ? 118 LEU A CD1 1 ATOM 785 C CD2 . LEU A 1 118 ? 43.711 53.330 24.515 1.00 17.22 ? 118 LEU A CD2 1 ATOM 786 N N . HIS A 1 119 ? 48.181 54.224 27.609 1.00 11.64 ? 119 HIS A N 1 ATOM 787 C CA . HIS A 1 119 ? 49.329 53.734 28.390 1.00 11.44 ? 119 HIS A CA 1 ATOM 788 C C . HIS A 1 119 ? 48.864 53.293 29.800 1.00 13.90 ? 119 HIS A C 1 ATOM 789 O O . HIS A 1 119 ? 49.190 52.189 30.247 1.00 14.16 ? 119 HIS A O 1 ATOM 790 C CB . HIS A 1 119 ? 50.340 54.859 28.549 1.00 14.29 ? 119 HIS A CB 1 ATOM 791 C CG . HIS A 1 119 ? 51.496 54.541 29.424 1.00 18.50 ? 119 HIS A CG 1 ATOM 792 N ND1 . HIS A 1 119 ? 51.550 54.897 30.761 1.00 22.46 ? 119 HIS A ND1 1 ATOM 793 C CD2 . HIS A 1 119 ? 52.680 53.952 29.136 1.00 19.60 ? 119 HIS A CD2 1 ATOM 794 C CE1 . HIS A 1 119 ? 52.726 54.538 31.257 1.00 24.04 ? 119 HIS A CE1 1 ATOM 795 N NE2 . HIS A 1 119 ? 53.431 53.962 30.293 1.00 23.50 ? 119 HIS A NE2 1 ATOM 796 N N . ASP A 1 120 ? 48.036 54.112 30.423 1.00 12.35 ? 120 ASP A N 1 ATOM 797 C CA . ASP A 1 120 ? 47.603 53.821 31.811 1.00 14.16 ? 120 ASP A CA 1 ATOM 798 C C . ASP A 1 120 ? 46.468 52.800 31.999 1.00 16.06 ? 120 ASP A C 1 ATOM 799 O O . ASP A 1 120 ? 46.231 52.331 33.140 1.00 16.37 ? 120 ASP A O 1 ATOM 800 C CB . ASP A 1 120 ? 47.148 55.119 32.472 1.00 14.72 ? 120 ASP A CB 1 ATOM 801 C CG . ASP A 1 120 ? 48.299 56.062 32.765 1.00 19.58 ? 120 ASP A CG 1 ATOM 802 O OD1 . ASP A 1 120 ? 49.456 55.628 32.699 1.00 21.12 ? 120 ASP A OD1 1 ATOM 803 O OD2 . ASP A 1 120 ? 48.042 57.253 33.054 1.00 24.29 ? 120 ASP A OD2 1 ATOM 804 N N . ASN A 1 121 ? 45.746 52.419 30.940 1.00 13.55 ? 121 ASN A N 1 ATOM 805 C CA . ASN A 1 121 ? 44.565 51.540 30.999 1.00 13.14 ? 121 ASN A CA 1 ATOM 806 C C . ASN A 1 121 ? 44.746 50.511 29.934 1.00 14.00 ? 121 ASN A C 1 ATOM 807 O O . ASN A 1 121 ? 44.246 50.656 28.808 1.00 13.00 ? 121 ASN A O 1 ATOM 808 C CB . ASN A 1 121 ? 43.260 52.345 30.790 1.00 12.52 ? 121 ASN A CB 1 ATOM 809 C CG . ASN A 1 121 ? 43.094 53.422 31.849 1.00 14.43 ? 121 ASN A CG 1 ATOM 810 O OD1 . ASN A 1 121 ? 43.441 54.612 31.646 1.00 16.48 ? 121 ASN A OD1 1 ATOM 811 N ND2 . ASN A 1 121 ? 42.603 53.002 33.030 1.00 14.17 ? 121 ASN A ND2 1 ATOM 812 N N . PRO A 1 122 ? 45.427 49.416 30.249 1.00 12.50 ? 122 PRO A N 1 ATOM 813 C CA . PRO A 1 122 ? 45.733 48.367 29.268 1.00 14.00 ? 122 PRO A CA 1 ATOM 814 C C . PRO A 1 122 ? 44.636 47.752 28.463 1.00 13.11 ? 122 PRO A C 1 ATOM 815 O O . PRO A 1 122 ? 44.903 47.238 27.329 1.00 15.40 ? 122 PRO A O 1 ATOM 816 C CB . PRO A 1 122 ? 46.532 47.314 30.082 1.00 15.75 ? 122 PRO A CB 1 ATOM 817 C CG . PRO A 1 122 ? 47.114 48.159 31.213 1.00 17.71 ? 122 PRO A CG 1 ATOM 818 C CD . PRO A 1 122 ? 45.984 49.096 31.598 1.00 14.94 ? 122 PRO A CD 1 ATOM 819 N N . GLU A 1 123 ? 43.408 47.747 28.979 1.00 13.83 ? 123 GLU A N 1 ATOM 820 C CA . GLU A 1 123 ? 42.314 47.158 28.225 1.00 14.18 ? 123 GLU A CA 1 ATOM 821 C C . GLU A 1 123 ? 41.590 48.148 27.294 1.00 13.06 ? 123 GLU A C 1 ATOM 822 O O . GLU A 1 123 ? 40.761 47.720 26.514 1.00 14.87 ? 123 GLU A O 1 ATOM 823 C CB . GLU A 1 123 ? 41.254 46.519 29.149 1.00 18.20 ? 123 GLU A CB 1 ATOM 824 C CG . GLU A 1 123 ? 41.788 45.294 29.968 1.00 29.63 ? 123 GLU A CG 1 ATOM 825 C CD . GLU A 1 123 ? 42.280 44.131 29.098 1.00 37.72 ? 123 GLU A CD 1 ATOM 826 O OE1 . GLU A 1 123 ? 41.468 43.494 28.365 1.00 42.86 ? 123 GLU A OE1 1 ATOM 827 O OE2 . GLU A 1 123 ? 43.503 43.852 29.150 1.00 43.52 ? 123 GLU A OE2 1 ATOM 828 N N . MET A 1 124 ? 41.889 49.446 27.432 1.00 12.64 ? 124 MET A N 1 ATOM 829 C CA . MET A 1 124 ? 41.249 50.451 26.574 1.00 10.78 ? 124 MET A CA 1 ATOM 830 C C . MET A 1 124 ? 41.882 50.347 25.164 1.00 11.60 ? 124 MET A C 1 ATOM 831 O O . MET A 1 124 ? 43.061 50.012 25.030 1.00 11.51 ? 124 MET A O 1 ATOM 832 C CB . MET A 1 124 ? 41.500 51.836 27.167 1.00 12.53 ? 124 MET A CB 1 ATOM 833 C CG . MET A 1 124 ? 40.688 52.985 26.505 1.00 13.54 ? 124 MET A CG 1 ATOM 834 S SD . MET A 1 124 ? 38.923 52.597 26.388 1.00 13.50 ? 124 MET A SD 1 ATOM 835 C CE . MET A 1 124 ? 38.339 54.069 25.547 1.00 15.28 ? 124 MET A CE 1 ATOM 836 N N . LYS A 1 125 ? 41.064 50.685 24.152 1.00 10.74 ? 125 LYS A N 1 ATOM 837 C CA . LYS A 1 125 ? 41.469 50.594 22.748 1.00 10.19 ? 125 LYS A CA 1 ATOM 838 C C . LYS A 1 125 ? 41.070 51.860 22.050 1.00 11.11 ? 125 LYS A C 1 ATOM 839 O O . LYS A 1 125 ? 40.222 52.615 22.520 1.00 10.54 ? 125 LYS A O 1 ATOM 840 C CB . LYS A 1 125 ? 40.729 49.432 22.099 1.00 12.23 ? 125 LYS A CB 1 ATOM 841 C CG . LYS A 1 125 ? 40.890 48.061 22.741 1.00 16.00 ? 125 LYS A CG 1 ATOM 842 C CD . LYS A 1 125 ? 42.279 47.536 22.465 1.00 17.29 ? 125 LYS A CD 1 ATOM 843 C CE . LYS A 1 125 ? 42.690 46.189 23.149 1.00 26.78 ? 125 LYS A CE 1 ATOM 844 N NZ . LYS A 1 125 ? 41.621 45.229 23.052 1.00 26.61 ? 125 LYS A NZ 1 ATOM 845 N N . PHE A 1 126 ? 41.671 52.086 20.855 1.00 9.36 ? 126 PHE A N 1 ATOM 846 C CA . PHE A 1 126 ? 41.341 53.322 20.105 1.00 9.09 ? 126 PHE A CA 1 ATOM 847 C C . PHE A 1 126 ? 41.814 53.068 18.659 1.00 8.97 ? 126 PHE A C 1 ATOM 848 O O . PHE A 1 126 ? 42.844 52.441 18.454 1.00 10.12 ? 126 PHE A O 1 ATOM 849 C CB . PHE A 1 126 ? 42.131 54.521 20.683 1.00 9.66 ? 126 PHE A CB 1 ATOM 850 C CG . PHE A 1 126 ? 41.726 55.871 20.170 1.00 8.27 ? 126 PHE A CG 1 ATOM 851 C CD1 . PHE A 1 126 ? 40.409 56.318 20.210 1.00 9.41 ? 126 PHE A CD1 1 ATOM 852 C CD2 . PHE A 1 126 ? 42.750 56.778 19.803 1.00 11.00 ? 126 PHE A CD2 1 ATOM 853 C CE1 . PHE A 1 126 ? 40.099 57.698 19.891 1.00 9.74 ? 126 PHE A CE1 1 ATOM 854 C CE2 . PHE A 1 126 ? 42.466 58.110 19.504 1.00 10.51 ? 126 PHE A CE2 1 ATOM 855 C CZ . PHE A 1 126 ? 41.164 58.572 19.546 1.00 8.46 ? 126 PHE A CZ 1 ATOM 856 N N . ILE A 1 127 ? 41.069 53.566 17.693 1.00 8.20 ? 127 ILE A N 1 ATOM 857 C CA . ILE A 1 127 ? 41.505 53.433 16.290 1.00 8.08 ? 127 ILE A CA 1 ATOM 858 C C . ILE A 1 127 ? 41.762 54.826 15.718 1.00 8.43 ? 127 ILE A C 1 ATOM 859 O O . ILE A 1 127 ? 41.139 55.824 16.134 1.00 9.03 ? 127 ILE A O 1 ATOM 860 C CB . ILE A 1 127 ? 40.522 52.673 15.373 1.00 8.28 ? 127 ILE A CB 1 ATOM 861 C CG1 . ILE A 1 127 ? 39.136 53.294 15.390 1.00 8.75 ? 127 ILE A CG1 1 ATOM 862 C CG2 . ILE A 1 127 ? 40.427 51.142 15.802 1.00 9.80 ? 127 ILE A CG2 1 ATOM 863 C CD1 . ILE A 1 127 ? 38.142 52.738 14.274 1.00 9.27 ? 127 ILE A CD1 1 ATOM 864 N N . TRP A 1 128 ? 42.692 54.897 14.767 1.00 8.77 ? 128 TRP A N 1 ATOM 865 C CA . TRP A 1 128 ? 43.102 56.201 14.168 1.00 8.23 ? 128 TRP A CA 1 ATOM 866 C C . TRP A 1 128 ? 43.228 56.025 12.649 1.00 7.77 ? 128 TRP A C 1 ATOM 867 O O . TRP A 1 128 ? 43.891 55.093 12.201 1.00 7.78 ? 128 TRP A O 1 ATOM 868 C CB . TRP A 1 128 ? 44.426 56.674 14.756 1.00 8.55 ? 128 TRP A CB 1 ATOM 869 C CG . TRP A 1 128 ? 44.703 58.093 14.391 1.00 8.10 ? 128 TRP A CG 1 ATOM 870 C CD1 . TRP A 1 128 ? 45.456 58.574 13.334 1.00 8.92 ? 128 TRP A CD1 1 ATOM 871 C CD2 . TRP A 1 128 ? 44.129 59.216 15.013 1.00 7.07 ? 128 TRP A CD2 1 ATOM 872 N NE1 . TRP A 1 128 ? 45.330 59.955 13.275 1.00 8.95 ? 128 TRP A NE1 1 ATOM 873 C CE2 . TRP A 1 128 ? 44.532 60.362 14.307 1.00 8.16 ? 128 TRP A CE2 1 ATOM 874 C CE3 . TRP A 1 128 ? 43.256 59.353 16.135 1.00 9.09 ? 128 TRP A CE3 1 ATOM 875 C CZ2 . TRP A 1 128 ? 44.121 61.648 14.671 1.00 9.30 ? 128 TRP A CZ2 1 ATOM 876 C CZ3 . TRP A 1 128 ? 42.856 60.621 16.481 1.00 9.67 ? 128 TRP A CZ3 1 ATOM 877 C CH2 . TRP A 1 128 ? 43.293 61.760 15.755 1.00 9.73 ? 128 TRP A CH2 1 ATOM 878 N N . ALA A 1 129 ? 42.673 56.981 11.909 1.00 8.82 ? 129 ALA A N 1 ATOM 879 C CA . ALA A 1 129 ? 42.725 56.887 10.440 1.00 8.86 ? 129 ALA A CA 1 ATOM 880 C C . ALA A 1 129 ? 43.644 57.851 9.702 1.00 10.33 ? 129 ALA A C 1 ATOM 881 O O . ALA A 1 129 ? 44.239 57.453 8.696 1.00 11.47 ? 129 ALA A O 1 ATOM 882 C CB . ALA A 1 129 ? 41.307 57.171 9.886 1.00 10.32 ? 129 ALA A CB 1 ATOM 883 N N . GLU A 1 130 ? 43.744 59.108 10.153 1.00 10.01 ? 130 GLU A N 1 ATOM 884 C CA . GLU A 1 130 ? 44.452 60.178 9.324 1.00 9.43 ? 130 GLU A CA 1 ATOM 885 C C . GLU A 1 130 ? 45.929 60.311 9.660 1.00 9.35 ? 130 GLU A C 1 ATOM 886 O O . GLU A 1 130 ? 46.308 60.882 10.748 1.00 9.75 ? 130 GLU A O 1 ATOM 887 C CB . GLU A 1 130 ? 43.774 61.531 9.531 1.00 12.21 ? 130 GLU A CB 1 ATOM 888 C CG . GLU A 1 130 ? 42.262 61.535 9.219 1.00 13.63 ? 130 GLU A CG 1 ATOM 889 C CD . GLU A 1 130 ? 41.434 60.966 10.295 1.00 16.37 ? 130 GLU A CD 1 ATOM 890 O OE1 . GLU A 1 130 ? 41.912 60.786 11.476 1.00 16.79 ? 130 GLU A OE1 1 ATOM 891 O OE2 . GLU A 1 130 ? 40.228 60.673 10.042 1.00 20.94 ? 130 GLU A OE2 1 ATOM 892 N N . ILE A 1 131 ? 46.798 59.822 8.797 1.00 8.57 ? 131 ILE A N 1 ATOM 893 C CA . ILE A 1 131 ? 48.223 59.847 9.090 1.00 8.63 ? 131 ILE A CA 1 ATOM 894 C C . ILE A 1 131 ? 48.783 61.246 8.921 1.00 9.96 ? 131 ILE A C 1 ATOM 895 O O . ILE A 1 131 ? 49.823 61.561 9.566 1.00 10.70 ? 131 ILE A O 1 ATOM 896 C CB . ILE A 1 131 ? 48.974 58.757 8.276 1.00 9.30 ? 131 ILE A CB 1 ATOM 897 C CG1 . ILE A 1 131 ? 48.322 57.398 8.595 1.00 9.33 ? 131 ILE A CG1 1 ATOM 898 C CG2 . ILE A 1 131 ? 50.461 58.753 8.587 1.00 10.60 ? 131 ILE A CG2 1 ATOM 899 C CD1 . ILE A 1 131 ? 48.233 57.049 10.122 1.00 11.39 ? 131 ILE A CD1 1 ATOM 900 N N . SER A 1 132 ? 48.180 62.135 8.160 1.00 8.13 ? 132 SER A N 1 ATOM 901 C CA . SER A 1 132 ? 48.703 63.509 8.104 1.00 7.62 ? 132 SER A CA 1 ATOM 902 C C . SER A 1 132 ? 48.764 64.099 9.547 1.00 7.90 ? 132 SER A C 1 ATOM 903 O O . SER A 1 132 ? 49.820 64.680 9.925 1.00 9.29 ? 132 SER A O 1 ATOM 904 C CB . SER A 1 132 ? 47.773 64.356 7.231 1.00 8.63 ? 132 SER A CB 1 ATOM 905 O OG . SER A 1 132 ? 46.395 64.282 7.662 1.00 8.81 ? 132 SER A OG 1 ATOM 906 N N . TYR A 1 133 ? 47.706 63.901 10.332 1.00 7.97 ? 133 TYR A N 1 ATOM 907 C CA . TYR A 1 133 ? 47.724 64.391 11.727 1.00 8.35 ? 133 TYR A CA 1 ATOM 908 C C . TYR A 1 133 ? 48.673 63.540 12.592 1.00 9.97 ? 133 TYR A C 1 ATOM 909 O O . TYR A 1 133 ? 49.393 64.126 13.437 1.00 10.83 ? 133 TYR A O 1 ATOM 910 C CB . TYR A 1 133 ? 46.339 64.303 12.366 1.00 9.20 ? 133 TYR A CB 1 ATOM 911 C CG . TYR A 1 133 ? 45.437 65.452 12.014 1.00 7.82 ? 133 TYR A CG 1 ATOM 912 C CD1 . TYR A 1 133 ? 44.173 65.241 11.517 1.00 8.30 ? 133 TYR A CD1 1 ATOM 913 C CD2 . TYR A 1 133 ? 45.877 66.782 12.262 1.00 9.29 ? 133 TYR A CD2 1 ATOM 914 C CE1 . TYR A 1 133 ? 43.298 66.302 11.291 1.00 8.75 ? 133 TYR A CE1 1 ATOM 915 C CE2 . TYR A 1 133 ? 45.030 67.860 12.017 1.00 9.80 ? 133 TYR A CE2 1 ATOM 916 C CZ . TYR A 1 133 ? 43.734 67.586 11.540 1.00 9.66 ? 133 TYR A CZ 1 ATOM 917 O OH . TYR A 1 133 ? 42.912 68.679 11.285 1.00 11.41 ? 133 TYR A OH 1 ATOM 918 N N . PHE A 1 134 ? 48.662 62.228 12.437 1.00 8.27 ? 134 PHE A N 1 ATOM 919 C CA . PHE A 1 134 ? 49.469 61.426 13.339 1.00 8.33 ? 134 PHE A CA 1 ATOM 920 C C . PHE A 1 134 ? 50.966 61.727 13.124 1.00 9.26 ? 134 PHE A C 1 ATOM 921 O O . PHE A 1 134 ? 51.733 61.826 14.112 1.00 10.20 ? 134 PHE A O 1 ATOM 922 C CB . PHE A 1 134 ? 49.182 59.943 13.132 1.00 8.27 ? 134 PHE A CB 1 ATOM 923 C CG . PHE A 1 134 ? 49.771 59.096 14.243 1.00 9.91 ? 134 PHE A CG 1 ATOM 924 C CD1 . PHE A 1 134 ? 49.055 58.911 15.449 1.00 10.32 ? 134 PHE A CD1 1 ATOM 925 C CD2 . PHE A 1 134 ? 51.038 58.586 14.139 1.00 11.08 ? 134 PHE A CD2 1 ATOM 926 C CE1 . PHE A 1 134 ? 49.647 58.207 16.535 1.00 10.42 ? 134 PHE A CE1 1 ATOM 927 C CE2 . PHE A 1 134 ? 51.651 57.877 15.219 1.00 12.18 ? 134 PHE A CE2 1 ATOM 928 C CZ . PHE A 1 134 ? 50.910 57.711 16.416 1.00 12.20 ? 134 PHE A CZ 1 ATOM 929 N N . ALA A 1 135 ? 51.417 61.873 11.875 1.00 10.12 ? 135 ALA A N 1 ATOM 930 C CA . ALA A 1 135 ? 52.842 62.171 11.601 1.00 10.35 ? 135 ALA A CA 1 ATOM 931 C C . ALA A 1 135 ? 53.157 63.572 12.189 1.00 11.81 ? 135 ALA A C 1 ATOM 932 O O . ALA A 1 135 ? 54.275 63.728 12.773 1.00 15.58 ? 135 ALA A O 1 ATOM 933 C CB . ALA A 1 135 ? 53.096 62.147 10.115 1.00 12.05 ? 135 ALA A CB 1 ATOM 934 N N . ARG A 1 136 ? 52.265 64.522 12.070 1.00 11.29 ? 136 ARG A N 1 ATOM 935 C CA . ARG A 1 136 ? 52.486 65.908 12.607 1.00 13.88 ? 136 ARG A CA 1 ATOM 936 C C . ARG A 1 136 ? 52.717 65.780 14.144 1.00 15.36 ? 136 ARG A C 1 ATOM 937 O O . ARG A 1 136 ? 53.680 66.366 14.710 1.00 19.57 ? 136 ARG A O 1 ATOM 938 C CB . ARG A 1 136 ? 51.247 66.768 12.339 1.00 15.50 ? 136 ARG A CB 1 ATOM 939 C CG . ARG A 1 136 ? 51.230 68.196 13.002 1.00 16.53 ? 136 ARG A CG 1 ATOM 940 C CD . ARG A 1 136 ? 51.903 69.258 12.091 1.00 19.52 ? 136 ARG A CD 1 ATOM 941 N NE . ARG A 1 136 ? 51.899 70.624 12.681 1.00 18.38 ? 136 ARG A NE 1 ATOM 942 C CZ . ARG A 1 136 ? 52.676 70.912 13.704 1.00 18.22 ? 136 ARG A CZ 1 ATOM 943 N NH1 . ARG A 1 136 ? 53.507 69.967 14.173 1.00 19.39 ? 136 ARG A NH1 1 ATOM 944 N NH2 . ARG A 1 136 ? 52.512 72.066 14.355 1.00 15.28 ? 136 ARG A NH2 1 ATOM 945 N N . PHE A 1 137 ? 51.904 64.970 14.831 1.00 11.46 ? 137 PHE A N 1 ATOM 946 C CA . PHE A 1 137 ? 51.990 64.768 16.263 1.00 10.83 ? 137 PHE A CA 1 ATOM 947 C C . PHE A 1 137 ? 53.241 64.023 16.636 1.00 10.38 ? 137 PHE A C 1 ATOM 948 O O . PHE A 1 137 ? 54.019 64.453 17.541 1.00 13.15 ? 137 PHE A O 1 ATOM 949 C CB . PHE A 1 137 ? 50.766 63.979 16.679 1.00 10.52 ? 137 PHE A CB 1 ATOM 950 C CG . PHE A 1 137 ? 50.724 63.721 18.148 1.00 11.97 ? 137 PHE A CG 1 ATOM 951 C CD1 . PHE A 1 137 ? 50.449 64.787 19.025 1.00 12.66 ? 137 PHE A CD1 1 ATOM 952 C CD2 . PHE A 1 137 ? 50.978 62.473 18.635 1.00 12.79 ? 137 PHE A CD2 1 ATOM 953 C CE1 . PHE A 1 137 ? 50.421 64.597 20.386 1.00 15.99 ? 137 PHE A CE1 1 ATOM 954 C CE2 . PHE A 1 137 ? 50.970 62.277 20.081 1.00 15.12 ? 137 PHE A CE2 1 ATOM 955 C CZ . PHE A 1 137 ? 50.681 63.355 20.903 1.00 14.37 ? 137 PHE A CZ 1 ATOM 956 N N . TYR A 1 138 ? 53.499 62.881 16.011 1.00 11.65 ? 138 TYR A N 1 ATOM 957 C CA . TYR A 1 138 ? 54.592 61.998 16.372 1.00 13.12 ? 138 TYR A CA 1 ATOM 958 C C . TYR A 1 138 ? 55.950 62.687 16.217 1.00 15.10 ? 138 TYR A C 1 ATOM 959 O O . TYR A 1 138 ? 56.816 62.559 17.117 1.00 14.64 ? 138 TYR A O 1 ATOM 960 C CB . TYR A 1 138 ? 54.555 60.701 15.522 1.00 13.77 ? 138 TYR A CB 1 ATOM 961 C CG . TYR A 1 138 ? 55.617 59.687 15.910 1.00 13.59 ? 138 TYR A CG 1 ATOM 962 C CD1 . TYR A 1 138 ? 55.362 58.789 16.913 1.00 14.15 ? 138 TYR A CD1 1 ATOM 963 C CD2 . TYR A 1 138 ? 56.834 59.630 15.251 1.00 15.33 ? 138 TYR A CD2 1 ATOM 964 C CE1 . TYR A 1 138 ? 56.293 57.824 17.291 1.00 17.50 ? 138 TYR A CE1 1 ATOM 965 C CE2 . TYR A 1 138 ? 57.810 58.649 15.615 1.00 13.59 ? 138 TYR A CE2 1 ATOM 966 C CZ . TYR A 1 138 ? 57.494 57.762 16.636 1.00 14.84 ? 138 TYR A CZ 1 ATOM 967 O OH . TYR A 1 138 ? 58.380 56.746 16.991 1.00 19.06 ? 138 TYR A OH 1 ATOM 968 N N . HIS A 1 139 ? 56.126 63.473 15.162 1.00 14.29 ? 139 HIS A N 1 ATOM 969 C CA . HIS A 1 139 ? 57.437 64.091 14.987 1.00 17.87 ? 139 HIS A CA 1 ATOM 970 C C . HIS A 1 139 ? 57.692 65.150 16.073 1.00 20.07 ? 139 HIS A C 1 ATOM 971 O O . HIS A 1 139 ? 58.857 65.510 16.351 1.00 23.41 ? 139 HIS A O 1 ATOM 972 C CB . HIS A 1 139 ? 57.540 64.634 13.552 1.00 19.49 ? 139 HIS A CB 1 ATOM 973 C CG . HIS A 1 139 ? 57.767 63.548 12.538 1.00 23.07 ? 139 HIS A CG 1 ATOM 974 N ND1 . HIS A 1 139 ? 58.856 62.689 12.596 1.00 29.12 ? 139 HIS A ND1 1 ATOM 975 C CD2 . HIS A 1 139 ? 57.054 63.185 11.437 1.00 24.70 ? 139 HIS A CD2 1 ATOM 976 C CE1 . HIS A 1 139 ? 58.804 61.858 11.561 1.00 29.51 ? 139 HIS A CE1 1 ATOM 977 N NE2 . HIS A 1 139 ? 57.727 62.144 10.838 1.00 25.74 ? 139 HIS A NE2 1 ATOM 978 N N . ASP A 1 140 ? 56.648 65.681 16.681 1.00 15.20 ? 140 ASP A N 1 ATOM 979 C CA . ASP A 1 140 ? 56.809 66.690 17.758 1.00 16.87 ? 140 ASP A CA 1 ATOM 980 C C . ASP A 1 140 ? 56.986 66.059 19.160 1.00 15.72 ? 140 ASP A C 1 ATOM 981 O O . ASP A 1 140 ? 57.328 66.782 20.125 1.00 17.66 ? 140 ASP A O 1 ATOM 982 C CB . ASP A 1 140 ? 55.621 67.639 17.813 1.00 18.77 ? 140 ASP A CB 1 ATOM 983 C CG . ASP A 1 140 ? 55.753 68.794 16.855 1.00 26.28 ? 140 ASP A CG 1 ATOM 984 O OD1 . ASP A 1 140 ? 56.613 68.716 15.982 1.00 25.68 ? 140 ASP A OD1 1 ATOM 985 O OD2 . ASP A 1 140 ? 54.992 69.775 17.011 1.00 27.15 ? 140 ASP A OD2 1 ATOM 986 N N . LEU A 1 141 ? 56.795 64.764 19.288 1.00 15.35 ? 141 LEU A N 1 ATOM 987 C CA . LEU A 1 141 ? 56.993 64.086 20.584 1.00 14.01 ? 141 LEU A CA 1 ATOM 988 C C . LEU A 1 141 ? 58.450 63.893 20.944 1.00 15.49 ? 141 LEU A C 1 ATOM 989 O O . LEU A 1 141 ? 59.275 63.655 20.100 1.00 15.82 ? 141 LEU A O 1 ATOM 990 C CB . LEU A 1 141 ? 56.420 62.647 20.556 1.00 14.07 ? 141 LEU A CB 1 ATOM 991 C CG . LEU A 1 141 ? 54.906 62.488 20.560 1.00 16.90 ? 141 LEU A CG 1 ATOM 992 C CD1 . LEU A 1 141 ? 54.617 60.945 20.487 1.00 14.32 ? 141 LEU A CD1 1 ATOM 993 C CD2 . LEU A 1 141 ? 54.265 63.156 21.818 1.00 14.91 ? 141 LEU A CD2 1 ATOM 994 N N . GLY A 1 142 ? 58.742 63.998 22.254 1.00 17.17 ? 142 GLY A N 1 ATOM 995 C CA . GLY A 1 142 ? 60.076 63.665 22.729 1.00 17.14 ? 142 GLY A CA 1 ATOM 996 C C . GLY A 1 142 ? 60.265 62.144 22.601 1.00 17.82 ? 142 GLY A C 1 ATOM 997 O O . GLY A 1 142 ? 59.283 61.363 22.458 1.00 16.73 ? 142 GLY A O 1 ATOM 998 N N . GLU A 1 143 ? 61.495 61.684 22.623 1.00 17.05 ? 143 GLU A N 1 ATOM 999 C CA . GLU A 1 143 ? 61.837 60.281 22.467 1.00 17.78 ? 143 GLU A CA 1 ATOM 1000 C C . GLU A 1 143 ? 61.151 59.358 23.468 1.00 17.01 ? 143 GLU A C 1 ATOM 1001 O O . GLU A 1 143 ? 60.701 58.246 23.097 1.00 16.77 ? 143 GLU A O 1 ATOM 1002 C CB . GLU A 1 143 ? 63.365 60.086 22.514 1.00 22.88 ? 143 GLU A CB 1 ATOM 1003 C CG . GLU A 1 143 ? 63.858 58.747 21.964 1.00 24.67 ? 143 GLU A CG 1 ATOM 1004 C CD . GLU A 1 143 ? 63.571 58.541 20.458 1.00 31.96 ? 143 GLU A CD 1 ATOM 1005 O OE1 . GLU A 1 143 ? 63.411 59.525 19.687 1.00 31.33 ? 143 GLU A OE1 1 ATOM 1006 O OE2 . GLU A 1 143 ? 63.533 57.372 20.043 1.00 36.28 ? 143 GLU A OE2 1 ATOM 1007 N N . ASN A 1 144 ? 61.016 59.773 24.727 1.00 16.94 ? 144 ASN A N 1 ATOM 1008 C CA . ASN A 1 144 ? 60.379 58.901 25.702 1.00 18.44 ? 144 ASN A CA 1 ATOM 1009 C C . ASN A 1 144 ? 58.925 58.580 25.274 1.00 15.97 ? 144 ASN A C 1 ATOM 1010 O O . ASN A 1 144 ? 58.492 57.396 25.296 1.00 16.48 ? 144 ASN A O 1 ATOM 1011 C CB . ASN A 1 144 ? 60.461 59.574 27.098 1.00 21.08 ? 144 ASN A CB 1 ATOM 1012 C CG . ASN A 1 144 ? 59.721 58.810 28.189 1.00 31.68 ? 144 ASN A CG 1 ATOM 1013 O OD1 . ASN A 1 144 ? 58.491 58.897 28.302 1.00 34.78 ? 144 ASN A OD1 1 ATOM 1014 N ND2 . ASN A 1 144 ? 60.465 58.041 28.994 1.00 32.42 ? 144 ASN A ND2 1 ATOM 1015 N N . LYS A 1 145 ? 58.210 59.620 24.871 1.00 16.09 ? 145 LYS A N 1 ATOM 1016 C CA . LYS A 1 145 ? 56.832 59.468 24.429 1.00 14.38 ? 145 LYS A CA 1 ATOM 1017 C C . LYS A 1 145 ? 56.764 58.753 23.064 1.00 13.89 ? 145 LYS A C 1 ATOM 1018 O O . LYS A 1 145 ? 55.816 58.008 22.877 1.00 14.22 ? 145 LYS A O 1 ATOM 1019 C CB . LYS A 1 145 ? 56.145 60.840 24.381 1.00 16.95 ? 145 LYS A CB 1 ATOM 1020 C CG . LYS A 1 145 ? 55.932 61.484 25.767 1.00 21.24 ? 145 LYS A CG 1 ATOM 1021 C CD . LYS A 1 145 ? 55.001 60.686 26.638 1.00 31.33 ? 145 LYS A CD 1 ATOM 1022 C CE . LYS A 1 145 ? 54.657 61.497 27.923 1.00 33.74 ? 145 LYS A CE 1 ATOM 1023 N NZ . LYS A 1 145 ? 55.813 62.283 28.484 1.00 41.73 ? 145 LYS A NZ 1 ATOM 1024 N N . LYS A 1 146 ? 57.716 58.959 22.153 1.00 13.91 ? 146 LYS A N 1 ATOM 1025 C CA . LYS A 1 146 ? 57.702 58.203 20.869 1.00 13.90 ? 146 LYS A CA 1 ATOM 1026 C C . LYS A 1 146 ? 57.740 56.743 21.246 1.00 14.02 ? 146 LYS A C 1 ATOM 1027 O O . LYS A 1 146 ? 56.989 55.926 20.674 1.00 14.06 ? 146 LYS A O 1 ATOM 1028 C CB . LYS A 1 146 ? 58.904 58.499 19.951 1.00 13.36 ? 146 LYS A CB 1 ATOM 1029 C CG . LYS A 1 146 ? 58.841 59.841 19.248 1.00 13.83 ? 146 LYS A CG 1 ATOM 1030 C CD . LYS A 1 146 ? 59.993 59.954 18.262 1.00 13.72 ? 146 LYS A CD 1 ATOM 1031 C CE . LYS A 1 146 ? 59.855 61.074 17.227 1.00 15.04 ? 146 LYS A CE 1 ATOM 1032 N NZ . LYS A 1 146 ? 60.005 62.384 17.881 1.00 19.35 ? 146 LYS A NZ 1 ATOM 1033 N N . LEU A 1 147 ? 58.595 56.348 22.209 1.00 15.31 ? 147 LEU A N 1 ATOM 1034 C CA . LEU A 1 147 ? 58.698 54.948 22.607 1.00 14.25 ? 147 LEU A CA 1 ATOM 1035 C C . LEU A 1 147 ? 57.400 54.425 23.251 1.00 12.79 ? 147 LEU A C 1 ATOM 1036 O O . LEU A 1 147 ? 56.995 53.304 22.943 1.00 13.33 ? 147 LEU A O 1 ATOM 1037 C CB . LEU A 1 147 ? 59.950 54.751 23.536 1.00 15.50 ? 147 LEU A CB 1 ATOM 1038 C CG . LEU A 1 147 ? 61.300 54.908 22.827 1.00 18.74 ? 147 LEU A CG 1 ATOM 1039 C CD1 . LEU A 1 147 ? 62.447 54.946 23.854 1.00 20.77 ? 147 LEU A CD1 1 ATOM 1040 C CD2 . LEU A 1 147 ? 61.494 53.747 21.908 1.00 21.20 ? 147 LEU A CD2 1 ATOM 1041 N N . GLN A 1 148 ? 56.735 55.226 24.093 1.00 13.40 ? 148 GLN A N 1 ATOM 1042 C CA . GLN A 1 148 ? 55.492 54.789 24.686 1.00 12.71 ? 148 GLN A CA 1 ATOM 1043 C C . GLN A 1 148 ? 54.459 54.583 23.562 1.00 12.59 ? 148 GLN A C 1 ATOM 1044 O O . GLN A 1 148 ? 53.675 53.646 23.634 1.00 13.64 ? 148 GLN A O 1 ATOM 1045 C CB . GLN A 1 148 ? 54.962 55.820 25.660 1.00 14.73 ? 148 GLN A CB 1 ATOM 1046 C CG . GLN A 1 148 ? 55.775 55.948 26.912 1.00 19.14 ? 148 GLN A CG 1 ATOM 1047 C CD . GLN A 1 148 ? 55.074 56.781 27.965 1.00 26.68 ? 148 GLN A CD 1 ATOM 1048 O OE1 . GLN A 1 148 ? 55.604 56.944 29.099 1.00 30.69 ? 148 GLN A OE1 1 ATOM 1049 N NE2 . GLN A 1 148 ? 53.890 57.294 27.640 1.00 24.51 ? 148 GLN A NE2 1 ATOM 1050 N N . MET A 1 149 ? 54.449 55.486 22.571 1.00 12.71 ? 149 MET A N 1 ATOM 1051 C CA . MET A 1 149 ? 53.480 55.385 21.458 1.00 11.05 ? 149 MET A CA 1 ATOM 1052 C C . MET A 1 149 ? 53.733 54.129 20.643 1.00 11.75 ? 149 MET A C 1 ATOM 1053 O O . MET A 1 149 ? 52.785 53.415 20.321 1.00 12.09 ? 149 MET A O 1 ATOM 1054 C CB . MET A 1 149 ? 53.582 56.657 20.599 1.00 13.14 ? 149 MET A CB 1 ATOM 1055 C CG . MET A 1 149 ? 52.588 56.678 19.411 1.00 12.09 ? 149 MET A CG 1 ATOM 1056 S SD . MET A 1 149 ? 50.902 56.793 19.961 1.00 14.74 ? 149 MET A SD 1 ATOM 1057 C CE . MET A 1 149 ? 50.725 58.551 20.071 1.00 21.46 ? 149 MET A CE 1 ATOM 1058 N N . LYS A 1 150 ? 55.000 53.831 20.340 1.00 11.75 ? 150 LYS A N 1 ATOM 1059 C CA . LYS A 1 150 ? 55.290 52.641 19.565 1.00 12.60 ? 150 LYS A CA 1 ATOM 1060 C C . LYS A 1 150 ? 54.835 51.405 20.363 1.00 11.79 ? 150 LYS A C 1 ATOM 1061 O O . LYS A 1 150 ? 54.335 50.435 19.764 1.00 14.35 ? 150 LYS A O 1 ATOM 1062 C CB . LYS A 1 150 ? 56.778 52.490 19.242 1.00 14.00 ? 150 LYS A CB 1 ATOM 1063 C CG . LYS A 1 150 ? 57.280 53.475 18.235 1.00 16.30 ? 150 LYS A CG 1 ATOM 1064 C CD . LYS A 1 150 ? 58.639 53.079 17.771 1.00 23.99 ? 150 LYS A CD 1 ATOM 1065 C CE . LYS A 1 150 ? 59.607 54.104 18.148 1.00 29.69 ? 150 LYS A CE 1 ATOM 1066 N NZ . LYS A 1 150 ? 60.953 53.785 17.604 1.00 34.53 ? 150 LYS A NZ 1 ATOM 1067 N N . SER A 1 151 ? 54.948 51.425 21.699 1.00 12.61 ? 151 SER A N 1 ATOM 1068 C CA . SER A 1 151 ? 54.531 50.274 22.493 1.00 13.98 ? 151 SER A CA 1 ATOM 1069 C C . SER A 1 151 ? 53.016 50.039 22.466 1.00 11.58 ? 151 SER A C 1 ATOM 1070 O O . SER A 1 151 ? 52.576 48.885 22.359 1.00 13.37 ? 151 SER A O 1 ATOM 1071 C CB . SER A 1 151 ? 54.987 50.471 23.957 1.00 15.75 ? 151 SER A CB 1 ATOM 1072 O OG . SER A 1 151 ? 54.815 49.215 24.618 1.00 21.34 ? 151 SER A OG 1 ATOM 1073 N N . ILE A 1 152 ? 52.200 51.101 22.596 1.00 12.06 ? 152 ILE A N 1 ATOM 1074 C CA . ILE A 1 152 ? 50.746 50.905 22.543 1.00 11.69 ? 152 ILE A CA 1 ATOM 1075 C C . ILE A 1 152 ? 50.263 50.489 21.149 1.00 11.06 ? 152 ILE A C 1 ATOM 1076 O O . ILE A 1 152 ? 49.199 49.919 21.043 1.00 12.50 ? 152 ILE A O 1 ATOM 1077 C CB . ILE A 1 152 ? 49.895 52.101 23.124 1.00 11.27 ? 152 ILE A CB 1 ATOM 1078 C CG1 . ILE A 1 152 ? 50.171 53.413 22.409 1.00 12.35 ? 152 ILE A CG1 1 ATOM 1079 C CG2 . ILE A 1 152 ? 50.180 52.221 24.672 1.00 13.46 ? 152 ILE A CG2 1 ATOM 1080 C CD1 . ILE A 1 152 ? 49.100 54.480 22.727 1.00 13.37 ? 152 ILE A CD1 1 ATOM 1081 N N . VAL A 1 153 ? 51.039 50.796 20.101 1.00 11.26 ? 153 VAL A N 1 ATOM 1082 C CA . VAL A 1 153 ? 50.698 50.326 18.741 1.00 11.48 ? 153 VAL A CA 1 ATOM 1083 C C . VAL A 1 153 ? 51.137 48.866 18.616 1.00 12.51 ? 153 VAL A C 1 ATOM 1084 O O . VAL A 1 153 ? 50.363 48.002 18.192 1.00 13.38 ? 153 VAL A O 1 ATOM 1085 C CB . VAL A 1 153 ? 51.359 51.207 17.717 1.00 11.95 ? 153 VAL A CB 1 ATOM 1086 C CG1 . VAL A 1 153 ? 51.236 50.582 16.288 1.00 12.90 ? 153 VAL A CG1 1 ATOM 1087 C CG2 . VAL A 1 153 ? 50.726 52.587 17.775 1.00 12.08 ? 153 VAL A CG2 1 ATOM 1088 N N . LYS A 1 154 ? 52.363 48.586 19.042 1.00 13.19 ? 154 LYS A N 1 ATOM 1089 C CA . LYS A 1 154 ? 52.877 47.214 18.891 1.00 14.71 ? 154 LYS A CA 1 ATOM 1090 C C . LYS A 1 154 ? 52.019 46.210 19.686 1.00 14.40 ? 154 LYS A C 1 ATOM 1091 O O . LYS A 1 154 ? 51.816 45.056 19.234 1.00 17.22 ? 154 LYS A O 1 ATOM 1092 C CB . LYS A 1 154 ? 54.348 47.158 19.347 1.00 16.20 ? 154 LYS A CB 1 ATOM 1093 C CG . LYS A 1 154 ? 55.008 45.767 19.129 1.00 20.75 ? 154 LYS A CG 1 ATOM 1094 C CD . LYS A 1 154 ? 56.501 45.896 19.437 1.00 22.98 ? 154 LYS A CD 1 ATOM 1095 C CE . LYS A 1 154 ? 57.287 44.653 18.992 1.00 28.81 ? 154 LYS A CE 1 ATOM 1096 N NZ . LYS A 1 154 ? 57.327 44.501 17.480 1.00 28.39 ? 154 LYS A NZ 1 ATOM 1097 N N . ASN A 1 155 ? 51.483 46.622 20.825 1.00 14.34 ? 155 ASN A N 1 ATOM 1098 C CA . ASN A 1 155 ? 50.651 45.752 21.721 1.00 15.60 ? 155 ASN A CA 1 ATOM 1099 C C . ASN A 1 155 ? 49.149 45.740 21.347 1.00 16.09 ? 155 ASN A C 1 ATOM 1100 O O . ASN A 1 155 ? 48.331 45.088 22.008 1.00 16.96 ? 155 ASN A O 1 ATOM 1101 C CB . ASN A 1 155 ? 50.814 46.144 23.247 1.00 21.67 ? 155 ASN A CB 1 ATOM 1102 C CG . ASN A 1 155 ? 49.913 47.404 23.686 1.00 24.06 ? 155 ASN A CG 1 ATOM 1103 O OD1 . ASN A 1 155 ? 49.156 47.875 22.877 1.00 26.36 ? 155 ASN A OD1 1 ATOM 1104 N ND2 . ASN A 1 155 ? 50.009 47.923 24.953 1.00 19.75 ? 155 ASN A ND2 1 ATOM 1105 N N . GLY A 1 156 ? 48.765 46.490 20.321 1.00 13.44 ? 156 GLY A N 1 ATOM 1106 C CA . GLY A 1 156 ? 47.375 46.418 19.850 1.00 14.25 ? 156 GLY A CA 1 ATOM 1107 C C . GLY A 1 156 ? 46.358 47.309 20.502 1.00 14.92 ? 156 GLY A C 1 ATOM 1108 O O . GLY A 1 156 ? 45.182 47.179 20.172 1.00 16.14 ? 156 GLY A O 1 ATOM 1109 N N . GLN A 1 157 ? 46.744 48.237 21.364 1.00 12.19 ? 157 GLN A N 1 ATOM 1110 C CA . GLN A 1 157 ? 45.772 49.119 21.973 1.00 11.75 ? 157 GLN A CA 1 ATOM 1111 C C . GLN A 1 157 ? 45.368 50.239 21.008 1.00 10.21 ? 157 GLN A C 1 ATOM 1112 O O . GLN A 1 157 ? 44.212 50.561 20.935 1.00 10.62 ? 157 GLN A O 1 ATOM 1113 C CB . GLN A 1 157 ? 46.323 49.762 23.243 1.00 10.10 ? 157 GLN A CB 1 ATOM 1114 C CG . GLN A 1 157 ? 46.279 48.814 24.443 1.00 12.12 ? 157 GLN A CG 1 ATOM 1115 C CD . GLN A 1 157 ? 46.597 49.604 25.676 1.00 10.11 ? 157 GLN A CD 1 ATOM 1116 O OE1 . GLN A 1 157 ? 45.730 50.298 26.258 1.00 13.14 ? 157 GLN A OE1 1 ATOM 1117 N NE2 . GLN A 1 157 ? 47.871 49.594 26.006 1.00 10.21 ? 157 GLN A NE2 1 ATOM 1118 N N . LEU A 1 158 ? 46.343 50.848 20.336 1.00 10.72 ? 158 LEU A N 1 ATOM 1119 C CA . LEU A 1 158 ? 46.057 51.908 19.342 1.00 10.22 ? 158 LEU A CA 1 ATOM 1120 C C . LEU A 1 158 ? 46.263 51.216 17.983 1.00 10.58 ? 158 LEU A C 1 ATOM 1121 O O . LEU A 1 158 ? 47.355 50.717 17.694 1.00 11.97 ? 158 LEU A O 1 ATOM 1122 C CB . LEU A 1 158 ? 47.068 53.038 19.518 1.00 11.77 ? 158 LEU A CB 1 ATOM 1123 C CG . LEU A 1 158 ? 47.008 54.102 18.440 1.00 17.00 ? 158 LEU A CG 1 ATOM 1124 C CD1 . LEU A 1 158 ? 45.710 54.735 18.471 1.00 15.83 ? 158 LEU A CD1 1 ATOM 1125 C CD2 . LEU A 1 158 ? 48.208 55.114 18.686 1.00 17.31 ? 158 LEU A CD2 1 ATOM 1126 N N . GLU A 1 159 ? 45.231 51.219 17.153 1.00 9.09 ? 159 GLU A N 1 ATOM 1127 C CA . GLU A 1 159 ? 45.344 50.570 15.844 1.00 8.91 ? 159 GLU A CA 1 ATOM 1128 C C . GLU A 1 159 ? 45.025 51.544 14.736 1.00 8.91 ? 159 GLU A C 1 ATOM 1129 O O . GLU A 1 159 ? 44.014 52.270 14.762 1.00 9.21 ? 159 GLU A O 1 ATOM 1130 C CB . GLU A 1 159 ? 44.322 49.422 15.812 1.00 10.90 ? 159 GLU A CB 1 ATOM 1131 C CG . GLU A 1 159 ? 44.310 48.662 14.501 1.00 11.21 ? 159 GLU A CG 1 ATOM 1132 C CD . GLU A 1 159 ? 43.301 47.541 14.556 1.00 13.47 ? 159 GLU A CD 1 ATOM 1133 O OE1 . GLU A 1 159 ? 43.640 46.516 15.258 1.00 14.61 ? 159 GLU A OE1 1 ATOM 1134 O OE2 . GLU A 1 159 ? 42.211 47.707 13.953 1.00 12.61 ? 159 GLU A OE2 1 ATOM 1135 N N . PHE A 1 160 ? 45.891 51.544 13.732 1.00 8.90 ? 160 PHE A N 1 ATOM 1136 C CA . PHE A 1 160 ? 45.645 52.375 12.549 1.00 8.17 ? 160 PHE A CA 1 ATOM 1137 C C . PHE A 1 160 ? 44.697 51.644 11.609 1.00 8.71 ? 160 PHE A C 1 ATOM 1138 O O . PHE A 1 160 ? 44.848 50.444 11.341 1.00 9.08 ? 160 PHE A O 1 ATOM 1139 C CB . PHE A 1 160 ? 46.983 52.708 11.866 1.00 8.41 ? 160 PHE A CB 1 ATOM 1140 C CG . PHE A 1 160 ? 47.867 53.536 12.745 1.00 8.94 ? 160 PHE A CG 1 ATOM 1141 C CD1 . PHE A 1 160 ? 48.944 52.950 13.434 1.00 10.16 ? 160 PHE A CD1 1 ATOM 1142 C CD2 . PHE A 1 160 ? 47.587 54.896 12.940 1.00 9.44 ? 160 PHE A CD2 1 ATOM 1143 C CE1 . PHE A 1 160 ? 49.709 53.757 14.283 1.00 10.44 ? 160 PHE A CE1 1 ATOM 1144 C CE2 . PHE A 1 160 ? 48.358 55.676 13.817 1.00 10.58 ? 160 PHE A CE2 1 ATOM 1145 C CZ . PHE A 1 160 ? 49.388 55.101 14.451 1.00 11.75 ? 160 PHE A CZ 1 ATOM 1146 N N . VAL A 1 161 ? 43.738 52.407 11.123 1.00 7.15 ? 161 VAL A N 1 ATOM 1147 C CA . VAL A 1 161 ? 42.730 51.914 10.189 1.00 7.77 ? 161 VAL A CA 1 ATOM 1148 C C . VAL A 1 161 ? 42.930 52.705 8.902 1.00 7.26 ? 161 VAL A C 1 ATOM 1149 O O . VAL A 1 161 ? 43.057 53.943 8.906 1.00 9.35 ? 161 VAL A O 1 ATOM 1150 C CB . VAL A 1 161 ? 41.269 52.001 10.764 1.00 7.10 ? 161 VAL A CB 1 ATOM 1151 C CG1 . VAL A 1 161 ? 41.138 50.983 11.914 1.00 9.29 ? 161 VAL A CG1 1 ATOM 1152 C CG2 . VAL A 1 161 ? 40.946 53.381 11.270 1.00 8.66 ? 161 VAL A CG2 1 ATOM 1153 N N . THR A 1 162 ? 43.009 51.962 7.792 1.00 7.64 ? 162 THR A N 1 ATOM 1154 C CA . THR A 1 162 ? 43.345 52.474 6.432 1.00 7.76 ? 162 THR A CA 1 ATOM 1155 C C . THR A 1 162 ? 44.828 52.929 6.403 1.00 6.94 ? 162 THR A C 1 ATOM 1156 O O . THR A 1 162 ? 45.649 52.354 5.685 1.00 9.19 ? 162 THR A O 1 ATOM 1157 C CB . THR A 1 162 ? 42.459 53.631 5.923 1.00 8.73 ? 162 THR A CB 1 ATOM 1158 O OG1 . THR A 1 162 ? 41.073 53.269 6.016 1.00 10.34 ? 162 THR A OG1 1 ATOM 1159 C CG2 . THR A 1 162 ? 42.759 53.888 4.383 1.00 10.55 ? 162 THR A CG2 1 ATOM 1160 N N . GLY A 1 163 ? 45.155 53.962 7.153 1.00 7.97 ? 163 GLY A N 1 ATOM 1161 C CA . GLY A 1 163 ? 46.533 54.401 7.165 1.00 9.08 ? 163 GLY A CA 1 ATOM 1162 C C . GLY A 1 163 ? 46.885 55.324 6.035 1.00 7.72 ? 163 GLY A C 1 ATOM 1163 O O . GLY A 1 163 ? 48.056 55.519 5.741 1.00 9.18 ? 163 GLY A O 1 ATOM 1164 N N . GLY A 1 164 ? 45.874 55.902 5.361 1.00 7.18 ? 164 GLY A N 1 ATOM 1165 C CA . GLY A 1 164 ? 46.192 56.928 4.362 1.00 7.91 ? 164 GLY A CA 1 ATOM 1166 C C . GLY A 1 164 ? 46.502 58.278 4.979 1.00 7.58 ? 164 GLY A C 1 ATOM 1167 O O . GLY A 1 164 ? 46.256 58.530 6.189 1.00 7.60 ? 164 GLY A O 1 ATOM 1168 N N . TRP A 1 165 ? 47.095 59.164 4.176 1.00 6.60 ? 165 TRP A N 1 ATOM 1169 C CA . TRP A 1 165 ? 47.331 60.530 4.675 1.00 5.91 ? 165 TRP A CA 1 ATOM 1170 C C . TRP A 1 165 ? 46.024 61.152 5.150 1.00 6.68 ? 165 TRP A C 1 ATOM 1171 O O . TRP A 1 165 ? 46.018 61.897 6.159 1.00 7.12 ? 165 TRP A O 1 ATOM 1172 C CB . TRP A 1 165 ? 47.999 61.345 3.520 1.00 6.19 ? 165 TRP A CB 1 ATOM 1173 C CG . TRP A 1 165 ? 48.762 62.510 3.974 1.00 6.64 ? 165 TRP A CG 1 ATOM 1174 C CD1 . TRP A 1 165 ? 48.529 63.809 3.664 1.00 8.84 ? 165 TRP A CD1 1 ATOM 1175 C CD2 . TRP A 1 165 ? 49.966 62.470 4.769 1.00 8.42 ? 165 TRP A CD2 1 ATOM 1176 N NE1 . TRP A 1 165 ? 49.529 64.627 4.241 1.00 9.89 ? 165 TRP A NE1 1 ATOM 1177 C CE2 . TRP A 1 165 ? 50.395 63.824 4.915 1.00 8.24 ? 165 TRP A CE2 1 ATOM 1178 C CE3 . TRP A 1 165 ? 50.703 61.437 5.351 1.00 8.71 ? 165 TRP A CE3 1 ATOM 1179 C CZ2 . TRP A 1 165 ? 51.565 64.181 5.678 1.00 10.84 ? 165 TRP A CZ2 1 ATOM 1180 C CZ3 . TRP A 1 165 ? 51.892 61.798 6.098 1.00 12.39 ? 165 TRP A CZ3 1 ATOM 1181 C CH2 . TRP A 1 165 ? 52.275 63.147 6.235 1.00 12.14 ? 165 TRP A CH2 1 ATOM 1182 N N . VAL A 1 166 ? 44.936 60.852 4.420 1.00 6.59 ? 166 VAL A N 1 ATOM 1183 C CA . VAL A 1 166 ? 43.600 61.339 4.752 1.00 6.43 ? 166 VAL A CA 1 ATOM 1184 C C . VAL A 1 166 ? 42.600 60.213 4.563 1.00 6.96 ? 166 VAL A C 1 ATOM 1185 O O . VAL A 1 166 ? 42.957 59.080 4.276 1.00 7.43 ? 166 VAL A O 1 ATOM 1186 C CB . VAL A 1 166 ? 43.170 62.561 3.827 1.00 7.00 ? 166 VAL A CB 1 ATOM 1187 C CG1 . VAL A 1 166 ? 44.204 63.698 3.941 1.00 7.65 ? 166 VAL A CG1 1 ATOM 1188 C CG2 . VAL A 1 166 ? 43.094 62.082 2.343 1.00 7.91 ? 166 VAL A CG2 1 ATOM 1189 N N . MET A 1 167 ? 41.339 60.544 4.810 1.00 7.27 ? 167 MET A N 1 ATOM 1190 C CA . MET A 1 167 ? 40.190 59.646 4.477 1.00 6.53 ? 167 MET A CA 1 ATOM 1191 C C . MET A 1 167 ? 39.635 60.389 3.244 1.00 7.48 ? 167 MET A C 1 ATOM 1192 O O . MET A 1 167 ? 38.865 61.343 3.366 1.00 8.18 ? 167 MET A O 1 ATOM 1193 C CB . MET A 1 167 ? 39.224 59.619 5.648 1.00 7.75 ? 167 MET A CB 1 ATOM 1194 C CG . MET A 1 167 ? 37.921 58.810 5.340 1.00 8.41 ? 167 MET A CG 1 ATOM 1195 S SD . MET A 1 167 ? 36.739 58.962 6.733 1.00 9.28 ? 167 MET A SD 1 ATOM 1196 C CE . MET A 1 167 ? 37.739 58.197 8.083 1.00 10.27 ? 167 MET A CE 1 ATOM 1197 N N . PRO A 1 168 ? 39.957 59.914 2.058 1.00 6.38 ? 168 PRO A N 1 ATOM 1198 C CA . PRO A 1 168 ? 39.567 60.683 0.875 1.00 8.38 ? 168 PRO A CA 1 ATOM 1199 C C . PRO A 1 168 ? 38.164 60.709 0.431 1.00 7.41 ? 168 PRO A C 1 ATOM 1200 O O . PRO A 1 168 ? 37.416 59.753 0.703 1.00 7.50 ? 168 PRO A O 1 ATOM 1201 C CB . PRO A 1 168 ? 40.480 60.069 -0.244 1.00 7.90 ? 168 PRO A CB 1 ATOM 1202 C CG . PRO A 1 168 ? 40.586 58.623 0.181 1.00 8.31 ? 168 PRO A CG 1 ATOM 1203 C CD . PRO A 1 168 ? 40.766 58.705 1.717 1.00 7.25 ? 168 PRO A CD 1 ATOM 1204 N N . ASP A 1 169 ? 37.807 61.804 -0.238 1.00 7.24 ? 169 ASP A N 1 ATOM 1205 C CA . ASP A 1 169 ? 36.577 61.806 -1.031 1.00 7.66 ? 169 ASP A CA 1 ATOM 1206 C C . ASP A 1 169 ? 36.700 60.635 -2.012 1.00 6.78 ? 169 ASP A C 1 ATOM 1207 O O . ASP A 1 169 ? 37.808 60.255 -2.470 1.00 7.48 ? 169 ASP A O 1 ATOM 1208 C CB . ASP A 1 169 ? 36.561 63.095 -1.839 1.00 7.70 ? 169 ASP A CB 1 ATOM 1209 C CG . ASP A 1 169 ? 35.373 63.170 -2.790 1.00 8.16 ? 169 ASP A CG 1 ATOM 1210 O OD1 . ASP A 1 169 ? 34.278 62.690 -2.471 1.00 8.41 ? 169 ASP A OD1 1 ATOM 1211 O OD2 . ASP A 1 169 ? 35.523 63.752 -3.865 1.00 10.25 ? 169 ASP A OD2 1 ATOM 1212 N N . GLU A 1 170 ? 35.565 60.018 -2.342 1.00 6.86 ? 170 GLU A N 1 ATOM 1213 C CA . GLU A 1 170 ? 35.531 58.906 -3.284 1.00 6.10 ? 170 GLU A CA 1 ATOM 1214 C C . GLU A 1 170 ? 34.808 59.273 -4.580 1.00 7.07 ? 170 GLU A C 1 ATOM 1215 O O . GLU A 1 170 ? 34.802 58.475 -5.534 1.00 7.19 ? 170 GLU A O 1 ATOM 1216 C CB . GLU A 1 170 ? 34.854 57.670 -2.632 1.00 7.87 ? 170 GLU A CB 1 ATOM 1217 C CG . GLU A 1 170 ? 35.692 57.219 -1.375 1.00 8.75 ? 170 GLU A CG 1 ATOM 1218 C CD . GLU A 1 170 ? 35.190 55.989 -0.675 1.00 9.78 ? 170 GLU A CD 1 ATOM 1219 O OE1 . GLU A 1 170 ? 34.429 55.218 -1.324 1.00 9.14 ? 170 GLU A OE1 1 ATOM 1220 O OE2 . GLU A 1 170 ? 35.580 55.779 0.525 1.00 10.50 ? 170 GLU A OE2 1 ATOM 1221 N N . ALA A 1 171 ? 34.234 60.461 -4.665 1.00 6.70 ? 171 ALA A N 1 ATOM 1222 C CA . ALA A 1 171 ? 33.517 60.829 -5.880 1.00 6.30 ? 171 ALA A CA 1 ATOM 1223 C C . ALA A 1 171 ? 34.372 61.592 -6.910 1.00 6.80 ? 171 ALA A C 1 ATOM 1224 O O . ALA A 1 171 ? 34.372 61.323 -8.105 1.00 7.73 ? 171 ALA A O 1 ATOM 1225 C CB . ALA A 1 171 ? 32.295 61.733 -5.507 1.00 8.55 ? 171 ALA A CB 1 ATOM 1226 N N . ASN A 1 172 ? 35.088 62.625 -6.420 1.00 6.90 ? 172 ASN A N 1 ATOM 1227 C CA . ASN A 1 172 ? 35.818 63.509 -7.333 1.00 6.50 ? 172 ASN A CA 1 ATOM 1228 C C . ASN A 1 172 ? 37.287 63.129 -7.504 1.00 6.67 ? 172 ASN A C 1 ATOM 1229 O O . ASN A 1 172 ? 37.960 63.593 -8.413 1.00 7.34 ? 172 ASN A O 1 ATOM 1230 C CB . ASN A 1 172 ? 35.763 64.928 -6.751 1.00 7.47 ? 172 ASN A CB 1 ATOM 1231 C CG . ASN A 1 172 ? 34.362 65.464 -6.622 1.00 9.87 ? 172 ASN A CG 1 ATOM 1232 O OD1 . ASN A 1 172 ? 33.680 65.684 -7.619 1.00 10.99 ? 172 ASN A OD1 1 ATOM 1233 N ND2 . ASN A 1 172 ? 33.954 65.769 -5.406 1.00 10.23 ? 172 ASN A ND2 1 ATOM 1234 N N . SER A 1 173 ? 37.814 62.349 -6.576 1.00 6.29 ? 173 SER A N 1 ATOM 1235 C CA . SER A 1 173 ? 39.245 61.990 -6.560 1.00 6.60 ? 173 SER A CA 1 ATOM 1236 C C . SER A 1 173 ? 39.632 61.089 -7.691 1.00 6.20 ? 173 SER A C 1 ATOM 1237 O O . SER A 1 173 ? 38.890 60.175 -8.091 1.00 8.00 ? 173 SER A O 1 ATOM 1238 C CB . SER A 1 173 ? 39.579 61.331 -5.240 1.00 6.84 ? 173 SER A CB 1 ATOM 1239 O OG . SER A 1 173 ? 38.651 60.210 -5.050 1.00 7.75 ? 173 SER A OG 1 ATOM 1240 N N . HIS A 1 174 ? 40.794 61.350 -8.266 1.00 5.77 ? 174 HIS A N 1 ATOM 1241 C CA . HIS A 1 174 ? 41.313 60.445 -9.287 1.00 5.46 ? 174 HIS A CA 1 ATOM 1242 C C . HIS A 1 174 ? 41.971 59.235 -8.571 1.00 5.16 ? 174 HIS A C 1 ATOM 1243 O O . HIS A 1 174 ? 42.610 59.428 -7.542 1.00 6.12 ? 174 HIS A O 1 ATOM 1244 C CB . HIS A 1 174 ? 42.360 61.169 -10.131 1.00 6.73 ? 174 HIS A CB 1 ATOM 1245 C CG . HIS A 1 174 ? 42.604 60.495 -11.417 1.00 6.30 ? 174 HIS A CG 1 ATOM 1246 N ND1 . HIS A 1 174 ? 43.368 59.340 -11.536 1.00 8.10 ? 174 HIS A ND1 1 ATOM 1247 C CD2 . HIS A 1 174 ? 42.134 60.806 -12.648 1.00 7.91 ? 174 HIS A CD2 1 ATOM 1248 C CE1 . HIS A 1 174 ? 43.334 58.972 -12.813 1.00 9.84 ? 174 HIS A CE1 1 ATOM 1249 N NE2 . HIS A 1 174 ? 42.596 59.831 -13.492 1.00 9.73 ? 174 HIS A NE2 1 ATOM 1250 N N . TRP A 1 175 ? 41.821 58.041 -9.150 1.00 5.54 ? 175 TRP A N 1 ATOM 1251 C CA . TRP A 1 175 ? 42.410 56.861 -8.515 1.00 5.89 ? 175 TRP A CA 1 ATOM 1252 C C . TRP A 1 175 ? 43.909 57.045 -8.290 1.00 6.06 ? 175 TRP A C 1 ATOM 1253 O O . TRP A 1 175 ? 44.425 56.530 -7.278 1.00 6.84 ? 175 TRP A O 1 ATOM 1254 C CB . TRP A 1 175 ? 42.122 55.595 -9.315 1.00 5.74 ? 175 TRP A CB 1 ATOM 1255 C CG . TRP A 1 175 ? 42.937 55.411 -10.570 1.00 6.42 ? 175 TRP A CG 1 ATOM 1256 C CD1 . TRP A 1 175 ? 42.611 55.782 -11.872 1.00 6.06 ? 175 TRP A CD1 1 ATOM 1257 C CD2 . TRP A 1 175 ? 44.221 54.772 -10.652 1.00 6.67 ? 175 TRP A CD2 1 ATOM 1258 N NE1 . TRP A 1 175 ? 43.643 55.400 -12.726 1.00 7.17 ? 175 TRP A NE1 1 ATOM 1259 C CE2 . TRP A 1 175 ? 44.627 54.771 -11.992 1.00 6.72 ? 175 TRP A CE2 1 ATOM 1260 C CE3 . TRP A 1 175 ? 45.079 54.184 -9.685 1.00 7.79 ? 175 TRP A CE3 1 ATOM 1261 C CZ2 . TRP A 1 175 ? 45.879 54.206 -12.424 1.00 8.36 ? 175 TRP A CZ2 1 ATOM 1262 C CZ3 . TRP A 1 175 ? 46.301 53.626 -10.111 1.00 9.15 ? 175 TRP A CZ3 1 ATOM 1263 C CH2 . TRP A 1 175 ? 46.680 53.651 -11.485 1.00 9.36 ? 175 TRP A CH2 1 ATOM 1264 N N . ARG A 1 176 ? 44.607 57.760 -9.194 1.00 6.67 ? 176 ARG A N 1 ATOM 1265 C CA . ARG A 1 176 ? 46.057 57.923 -8.997 1.00 6.87 ? 176 ARG A CA 1 ATOM 1266 C C . ARG A 1 176 ? 46.304 58.674 -7.696 1.00 5.74 ? 176 ARG A C 1 ATOM 1267 O O . ARG A 1 176 ? 47.310 58.401 -7.000 1.00 6.86 ? 176 ARG A O 1 ATOM 1268 C CB . ARG A 1 176 ? 46.651 58.691 -10.213 1.00 7.77 ? 176 ARG A CB 1 ATOM 1269 C CG . ARG A 1 176 ? 46.642 57.813 -11.459 1.00 9.78 ? 176 ARG A CG 1 ATOM 1270 C CD . ARG A 1 176 ? 46.601 58.636 -12.762 1.00 12.40 ? 176 ARG A CD 1 ATOM 1271 N NE . ARG A 1 176 ? 47.703 59.546 -12.870 1.00 12.14 ? 176 ARG A NE 1 ATOM 1272 C CZ . ARG A 1 176 ? 47.851 60.401 -13.907 1.00 10.20 ? 176 ARG A CZ 1 ATOM 1273 N NH1 . ARG A 1 176 ? 46.913 60.392 -14.870 1.00 12.58 ? 176 ARG A NH1 1 ATOM 1274 N NH2 . ARG A 1 176 ? 48.799 61.309 -13.876 1.00 12.17 ? 176 ARG A NH2 1 ATOM 1275 N N . ASN A 1 177 ? 45.457 59.654 -7.347 1.00 5.64 ? 177 ASN A N 1 ATOM 1276 C CA . ASN A 1 177 ? 45.669 60.402 -6.110 1.00 5.78 ? 177 ASN A CA 1 ATOM 1277 C C . ASN A 1 177 ? 45.163 59.681 -4.882 1.00 6.54 ? 177 ASN A C 1 ATOM 1278 O O . ASN A 1 177 ? 45.701 59.887 -3.778 1.00 6.90 ? 177 ASN A O 1 ATOM 1279 C CB . ASN A 1 177 ? 45.076 61.828 -6.220 1.00 6.38 ? 177 ASN A CB 1 ATOM 1280 C CG . ASN A 1 177 ? 45.754 62.639 -7.256 1.00 7.80 ? 177 ASN A CG 1 ATOM 1281 O OD1 . ASN A 1 177 ? 46.922 62.431 -7.583 1.00 8.17 ? 177 ASN A OD1 1 ATOM 1282 N ND2 . ASN A 1 177 ? 44.967 63.582 -7.818 1.00 10.17 ? 177 ASN A ND2 1 ATOM 1283 N N . VAL A 1 178 ? 44.184 58.816 -5.043 1.00 7.08 ? 178 VAL A N 1 ATOM 1284 C CA . VAL A 1 178 ? 43.751 58.002 -3.911 1.00 6.59 ? 178 VAL A CA 1 ATOM 1285 C C . VAL A 1 178 ? 44.960 57.068 -3.586 1.00 6.16 ? 178 VAL A C 1 ATOM 1286 O O . VAL A 1 178 ? 45.294 56.870 -2.401 1.00 7.21 ? 178 VAL A O 1 ATOM 1287 C CB . VAL A 1 178 ? 42.530 57.129 -4.296 1.00 6.90 ? 178 VAL A CB 1 ATOM 1288 C CG1 . VAL A 1 178 ? 42.200 56.134 -3.190 1.00 8.37 ? 178 VAL A CG1 1 ATOM 1289 C CG2 . VAL A 1 178 ? 41.302 58.028 -4.502 1.00 8.78 ? 178 VAL A CG2 1 ATOM 1290 N N . LEU A 1 179 ? 45.611 56.513 -4.609 1.00 5.83 ? 179 LEU A N 1 ATOM 1291 C CA . LEU A 1 179 ? 46.760 55.674 -4.339 1.00 6.88 ? 179 LEU A CA 1 ATOM 1292 C C . LEU A 1 179 ? 47.926 56.503 -3.768 1.00 6.83 ? 179 LEU A C 1 ATOM 1293 O O . LEU A 1 179 ? 48.583 56.044 -2.808 1.00 7.53 ? 179 LEU A O 1 ATOM 1294 C CB . LEU A 1 179 ? 47.201 54.995 -5.667 1.00 6.56 ? 179 LEU A CB 1 ATOM 1295 C CG . LEU A 1 179 ? 48.533 54.173 -5.492 1.00 7.13 ? 179 LEU A CG 1 ATOM 1296 C CD1 . LEU A 1 179 ? 48.435 53.061 -4.412 1.00 8.83 ? 179 LEU A CD1 1 ATOM 1297 C CD2 . LEU A 1 179 ? 48.886 53.535 -6.859 1.00 9.95 ? 179 LEU A CD2 1 ATOM 1298 N N . LEU A 1 180 ? 48.137 57.718 -4.257 1.00 5.89 ? 180 LEU A N 1 ATOM 1299 C CA . LEU A 1 180 ? 49.230 58.563 -3.779 1.00 6.19 ? 180 LEU A CA 1 ATOM 1300 C C . LEU A 1 180 ? 49.061 58.813 -2.281 1.00 5.79 ? 180 LEU A C 1 ATOM 1301 O O . LEU A 1 180 ? 50.040 58.608 -1.487 1.00 7.17 ? 180 LEU A O 1 ATOM 1302 C CB . LEU A 1 180 ? 49.219 59.884 -4.550 1.00 7.55 ? 180 LEU A CB 1 ATOM 1303 C CG . LEU A 1 180 ? 50.349 60.851 -4.147 1.00 8.23 ? 180 LEU A CG 1 ATOM 1304 C CD1 . LEU A 1 180 ? 51.603 60.364 -4.801 1.00 11.43 ? 180 LEU A CD1 1 ATOM 1305 C CD2 . LEU A 1 180 ? 49.979 62.244 -4.679 1.00 10.65 ? 180 LEU A CD2 1 ATOM 1306 N N . GLN A 1 181 ? 47.846 59.186 -1.852 1.00 6.28 ? 181 GLN A N 1 ATOM 1307 C CA . GLN A 1 181 ? 47.690 59.513 -0.431 1.00 6.72 ? 181 GLN A CA 1 ATOM 1308 C C . GLN A 1 181 ? 47.758 58.264 0.449 1.00 6.05 ? 181 GLN A C 1 ATOM 1309 O O . GLN A 1 181 ? 48.269 58.325 1.598 1.00 6.68 ? 181 GLN A O 1 ATOM 1310 C CB . GLN A 1 181 ? 46.421 60.353 -0.203 1.00 6.60 ? 181 GLN A CB 1 ATOM 1311 C CG . GLN A 1 181 ? 45.119 59.612 -0.430 1.00 6.68 ? 181 GLN A CG 1 ATOM 1312 C CD . GLN A 1 181 ? 44.728 58.705 0.701 1.00 7.03 ? 181 GLN A CD 1 ATOM 1313 O OE1 . GLN A 1 181 ? 45.001 58.983 1.884 1.00 8.29 ? 181 GLN A OE1 1 ATOM 1314 N NE2 . GLN A 1 181 ? 44.052 57.603 0.360 1.00 7.98 ? 181 GLN A NE2 1 ATOM 1315 N N . LEU A 1 182 ? 47.246 57.132 -0.045 1.00 6.86 ? 182 LEU A N 1 ATOM 1316 C CA . LEU A 1 182 ? 47.350 55.885 0.696 1.00 6.60 ? 182 LEU A CA 1 ATOM 1317 C C . LEU A 1 182 ? 48.821 55.533 0.899 1.00 6.70 ? 182 LEU A C 1 ATOM 1318 O O . LEU A 1 182 ? 49.243 55.143 2.002 1.00 7.33 ? 182 LEU A O 1 ATOM 1319 C CB . LEU A 1 182 ? 46.633 54.762 -0.071 1.00 7.11 ? 182 LEU A CB 1 ATOM 1320 C CG . LEU A 1 182 ? 46.730 53.428 0.640 1.00 6.91 ? 182 LEU A CG 1 ATOM 1321 C CD1 . LEU A 1 182 ? 45.912 53.371 1.964 1.00 9.52 ? 182 LEU A CD1 1 ATOM 1322 C CD2 . LEU A 1 182 ? 46.145 52.340 -0.309 1.00 8.91 ? 182 LEU A CD2 1 ATOM 1323 N N . THR A 1 183 ? 49.609 55.676 -0.150 1.00 6.84 ? 183 THR A N 1 ATOM 1324 C CA . THR A 1 183 ? 51.032 55.335 -0.096 1.00 6.29 ? 183 THR A CA 1 ATOM 1325 C C . THR A 1 183 ? 51.750 56.295 0.829 1.00 6.92 ? 183 THR A C 1 ATOM 1326 O O . THR A 1 183 ? 52.664 55.876 1.574 1.00 7.16 ? 183 THR A O 1 ATOM 1327 C CB . THR A 1 183 ? 51.648 55.413 -1.518 1.00 6.92 ? 183 THR A CB 1 ATOM 1328 O OG1 . THR A 1 183 ? 50.971 54.494 -2.393 1.00 7.81 ? 183 THR A OG1 1 ATOM 1329 C CG2 . THR A 1 183 ? 53.132 54.999 -1.500 1.00 8.56 ? 183 THR A CG2 1 ATOM 1330 N N . GLU A 1 184 ? 51.411 57.565 0.832 1.00 7.00 ? 184 GLU A N 1 ATOM 1331 C CA . GLU A 1 184 ? 52.107 58.523 1.680 1.00 7.12 ? 184 GLU A CA 1 ATOM 1332 C C . GLU A 1 184 ? 51.879 58.137 3.141 1.00 7.11 ? 184 GLU A C 1 ATOM 1333 O O . GLU A 1 184 ? 52.835 58.124 3.949 1.00 8.98 ? 184 GLU A O 1 ATOM 1334 C CB . GLU A 1 184 ? 51.548 59.931 1.440 1.00 8.76 ? 184 GLU A CB 1 ATOM 1335 C CG . GLU A 1 184 ? 52.461 61.036 1.964 1.00 12.30 ? 184 GLU A CG 1 ATOM 1336 C CD . GLU A 1 184 ? 53.823 61.092 1.233 1.00 11.27 ? 184 GLU A CD 1 ATOM 1337 O OE1 . GLU A 1 184 ? 53.980 60.698 0.069 1.00 12.66 ? 184 GLU A OE1 1 ATOM 1338 O OE2 . GLU A 1 184 ? 54.738 61.577 1.937 1.00 15.36 ? 184 GLU A OE2 1 ATOM 1339 N N . GLY A 1 185 ? 50.642 57.858 3.540 1.00 6.90 ? 185 GLY A N 1 ATOM 1340 C CA . GLY A 1 185 ? 50.412 57.489 4.924 1.00 7.15 ? 185 GLY A CA 1 ATOM 1341 C C . GLY A 1 185 ? 51.000 56.135 5.280 1.00 7.23 ? 185 GLY A C 1 ATOM 1342 O O . GLY A 1 185 ? 51.601 55.980 6.385 1.00 7.83 ? 185 GLY A O 1 ATOM 1343 N N . GLN A 1 186 ? 50.874 55.139 4.399 1.00 7.48 ? 186 GLN A N 1 ATOM 1344 C CA . GLN A 1 186 ? 51.350 53.800 4.787 1.00 7.05 ? 186 GLN A CA 1 ATOM 1345 C C . GLN A 1 186 ? 52.856 53.758 4.786 1.00 6.92 ? 186 GLN A C 1 ATOM 1346 O O . GLN A 1 186 ? 53.445 52.980 5.558 1.00 8.06 ? 186 GLN A O 1 ATOM 1347 C CB . GLN A 1 186 ? 50.777 52.724 3.855 1.00 7.24 ? 186 GLN A CB 1 ATOM 1348 C CG . GLN A 1 186 ? 49.235 52.555 4.096 1.00 9.45 ? 186 GLN A CG 1 ATOM 1349 C CD . GLN A 1 186 ? 48.802 51.175 3.854 1.00 10.21 ? 186 GLN A CD 1 ATOM 1350 O OE1 . GLN A 1 186 ? 49.438 50.483 3.056 1.00 12.70 ? 186 GLN A OE1 1 ATOM 1351 N NE2 . GLN A 1 186 ? 47.782 50.713 4.531 1.00 10.02 ? 186 GLN A NE2 1 ATOM 1352 N N . THR A 1 187 ? 53.528 54.494 3.897 1.00 8.62 ? 187 THR A N 1 ATOM 1353 C CA . THR A 1 187 ? 54.989 54.498 3.902 1.00 8.32 ? 187 THR A CA 1 ATOM 1354 C C . THR A 1 187 ? 55.486 55.089 5.232 1.00 8.99 ? 187 THR A C 1 ATOM 1355 O O . THR A 1 187 ? 56.439 54.552 5.839 1.00 9.28 ? 187 THR A O 1 ATOM 1356 C CB . THR A 1 187 ? 55.527 55.274 2.703 1.00 8.06 ? 187 THR A CB 1 ATOM 1357 O OG1 . THR A 1 187 ? 55.028 54.617 1.509 1.00 8.86 ? 187 THR A OG1 1 ATOM 1358 C CG2 . THR A 1 187 ? 57.073 55.259 2.664 1.00 9.51 ? 187 THR A CG2 1 ATOM 1359 N N . TRP A 1 188 ? 54.851 56.146 5.708 1.00 7.73 ? 188 TRP A N 1 ATOM 1360 C CA . TRP A 1 188 ? 55.211 56.736 7.007 1.00 9.08 ? 188 TRP A CA 1 ATOM 1361 C C . TRP A 1 188 ? 54.940 55.677 8.109 1.00 8.77 ? 188 TRP A C 1 ATOM 1362 O O . TRP A 1 188 ? 55.834 55.428 8.973 1.00 8.78 ? 188 TRP A O 1 ATOM 1363 C CB . TRP A 1 188 ? 54.377 57.993 7.242 1.00 9.64 ? 188 TRP A CB 1 ATOM 1364 C CG . TRP A 1 188 ? 54.802 58.760 8.464 1.00 9.45 ? 188 TRP A CG 1 ATOM 1365 C CD1 . TRP A 1 188 ? 55.712 59.785 8.486 1.00 10.72 ? 188 TRP A CD1 1 ATOM 1366 C CD2 . TRP A 1 188 ? 54.453 58.470 9.842 1.00 9.91 ? 188 TRP A CD2 1 ATOM 1367 N NE1 . TRP A 1 188 ? 55.965 60.164 9.792 1.00 11.81 ? 188 TRP A NE1 1 ATOM 1368 C CE2 . TRP A 1 188 ? 55.218 59.362 10.643 1.00 10.40 ? 188 TRP A CE2 1 ATOM 1369 C CE3 . TRP A 1 188 ? 53.604 57.544 10.461 1.00 9.64 ? 188 TRP A CE3 1 ATOM 1370 C CZ2 . TRP A 1 188 ? 55.156 59.351 12.041 1.00 11.24 ? 188 TRP A CZ2 1 ATOM 1371 C CZ3 . TRP A 1 188 ? 53.562 57.508 11.864 1.00 10.47 ? 188 TRP A CZ3 1 ATOM 1372 C CH2 . TRP A 1 188 ? 54.342 58.423 12.621 1.00 11.49 ? 188 TRP A CH2 1 ATOM 1373 N N . LEU A 1 189 ? 53.803 55.010 8.107 1.00 8.20 ? 189 LEU A N 1 ATOM 1374 C CA . LEU A 1 189 ? 53.537 54.013 9.142 1.00 8.38 ? 189 LEU A CA 1 ATOM 1375 C C . LEU A 1 189 ? 54.528 52.895 9.111 1.00 9.46 ? 189 LEU A C 1 ATOM 1376 O O . LEU A 1 189 ? 54.937 52.398 10.225 1.00 10.60 ? 189 LEU A O 1 ATOM 1377 C CB . LEU A 1 189 ? 52.099 53.442 8.968 1.00 8.94 ? 189 LEU A CB 1 ATOM 1378 C CG . LEU A 1 189 ? 50.978 54.324 9.445 1.00 7.93 ? 189 LEU A CG 1 ATOM 1379 C CD1 . LEU A 1 189 ? 49.622 53.662 9.124 1.00 10.46 ? 189 LEU A CD1 1 ATOM 1380 C CD2 . LEU A 1 189 ? 51.076 54.522 11.002 1.00 10.32 ? 189 LEU A CD2 1 ATOM 1381 N N . LYS A 1 190 ? 54.927 52.406 7.961 1.00 8.43 ? 190 LYS A N 1 ATOM 1382 C CA . LYS A 1 190 ? 55.868 51.298 7.948 1.00 9.34 ? 190 LYS A CA 1 ATOM 1383 C C . LYS A 1 190 ? 57.217 51.776 8.548 1.00 10.37 ? 190 LYS A C 1 ATOM 1384 O O . LYS A 1 190 ? 57.824 51.057 9.371 1.00 12.13 ? 190 LYS A O 1 ATOM 1385 C CB . LYS A 1 190 ? 56.133 50.774 6.524 1.00 11.99 ? 190 LYS A CB 1 ATOM 1386 C CG . LYS A 1 190 ? 57.065 49.554 6.514 1.00 14.48 ? 190 LYS A CG 1 ATOM 1387 C CD . LYS A 1 190 ? 57.273 49.060 5.108 1.00 18.32 ? 190 LYS A CD 1 ATOM 1388 C CE . LYS A 1 190 ? 58.023 47.725 5.122 1.00 24.75 ? 190 LYS A CE 1 ATOM 1389 N NZ . LYS A 1 190 ? 58.421 47.374 3.670 1.00 23.55 ? 190 LYS A NZ 1 ATOM 1390 N N . GLN A 1 191 ? 57.669 52.955 8.183 1.00 10.63 ? 191 GLN A N 1 ATOM 1391 C CA . GLN A 1 191 ? 58.950 53.444 8.652 1.00 13.29 ? 191 GLN A CA 1 ATOM 1392 C C . GLN A 1 191 ? 58.959 53.716 10.148 1.00 13.62 ? 191 GLN A C 1 ATOM 1393 O O . GLN A 1 191 ? 59.902 53.255 10.849 1.00 17.86 ? 191 GLN A O 1 ATOM 1394 C CB . GLN A 1 191 ? 59.330 54.721 7.885 1.00 14.30 ? 191 GLN A CB 1 ATOM 1395 C CG . GLN A 1 191 ? 60.725 55.285 8.313 1.00 23.37 ? 191 GLN A CG 1 ATOM 1396 C CD . GLN A 1 191 ? 61.168 56.513 7.469 1.00 24.48 ? 191 GLN A CD 1 ATOM 1397 O OE1 . GLN A 1 191 ? 60.498 56.920 6.495 1.00 31.05 ? 191 GLN A OE1 1 ATOM 1398 N NE2 . GLN A 1 191 ? 62.288 57.105 7.862 1.00 33.50 ? 191 GLN A NE2 1 ATOM 1399 N N . PHE A 1 192 ? 57.981 54.418 10.681 1.00 11.86 ? 192 PHE A N 1 ATOM 1400 C CA . PHE A 1 192 ? 58.000 54.833 12.066 1.00 11.54 ? 192 PHE A CA 1 ATOM 1401 C C . PHE A 1 192 ? 57.248 53.961 13.036 1.00 14.99 ? 192 PHE A C 1 ATOM 1402 O O . PHE A 1 192 ? 57.646 53.899 14.212 1.00 16.58 ? 192 PHE A O 1 ATOM 1403 C CB . PHE A 1 192 ? 57.499 56.277 12.176 1.00 10.31 ? 192 PHE A CB 1 ATOM 1404 C CG . PHE A 1 192 ? 58.404 57.258 11.455 1.00 11.97 ? 192 PHE A CG 1 ATOM 1405 C CD1 . PHE A 1 192 ? 58.105 57.720 10.166 1.00 12.86 ? 192 PHE A CD1 1 ATOM 1406 C CD2 . PHE A 1 192 ? 59.657 57.644 12.056 1.00 15.09 ? 192 PHE A CD2 1 ATOM 1407 C CE1 . PHE A 1 192 ? 58.986 58.541 9.477 1.00 14.32 ? 192 PHE A CE1 1 ATOM 1408 C CE2 . PHE A 1 192 ? 60.561 58.483 11.338 1.00 16.52 ? 192 PHE A CE2 1 ATOM 1409 C CZ . PHE A 1 192 ? 60.246 58.926 10.098 1.00 14.32 ? 192 PHE A CZ 1 ATOM 1410 N N . MET A 1 193 ? 56.193 53.259 12.621 1.00 11.53 ? 193 MET A N 1 ATOM 1411 C CA . MET A 1 193 ? 55.388 52.454 13.531 1.00 10.83 ? 193 MET A CA 1 ATOM 1412 C C . MET A 1 193 ? 55.602 50.965 13.284 1.00 11.37 ? 193 MET A C 1 ATOM 1413 O O . MET A 1 193 ? 54.965 50.154 13.999 1.00 13.28 ? 193 MET A O 1 ATOM 1414 C CB . MET A 1 193 ? 53.906 52.810 13.393 1.00 12.28 ? 193 MET A CB 1 ATOM 1415 C CG . MET A 1 193 ? 53.583 54.257 13.728 1.00 15.61 ? 193 MET A CG 1 ATOM 1416 S SD . MET A 1 193 ? 54.169 54.741 15.364 1.00 44.06 ? 193 MET A SD 1 ATOM 1417 C CE . MET A 1 193 ? 55.426 55.940 14.933 1.00 30.71 ? 193 MET A CE 1 ATOM 1418 N N . ASN A 1 194 ? 56.219 50.602 12.155 1.00 11.00 ? 194 ASN A N 1 ATOM 1419 C CA . ASN A 1 194 ? 56.366 49.215 11.747 1.00 12.19 ? 194 ASN A CA 1 ATOM 1420 C C . ASN A 1 194 ? 55.026 48.431 11.625 1.00 14.26 ? 194 ASN A C 1 ATOM 1421 O O . ASN A 1 194 ? 54.906 47.289 12.090 1.00 14.30 ? 194 ASN A O 1 ATOM 1422 C CB . ASN A 1 194 ? 57.295 48.487 12.769 1.00 14.11 ? 194 ASN A CB 1 ATOM 1423 C CG . ASN A 1 194 ? 57.765 47.146 12.260 1.00 17.04 ? 194 ASN A CG 1 ATOM 1424 O OD1 . ASN A 1 194 ? 57.869 46.906 11.076 1.00 17.90 ? 194 ASN A OD1 1 ATOM 1425 N ND2 . ASN A 1 194 ? 58.047 46.259 13.194 1.00 20.21 ? 194 ASN A ND2 1 ATOM 1426 N N . VAL A 1 195 ? 54.013 49.064 11.028 1.00 11.94 ? 195 VAL A N 1 ATOM 1427 C CA . VAL A 1 195 ? 52.726 48.375 10.817 1.00 10.96 ? 195 VAL A CA 1 ATOM 1428 C C . VAL A 1 195 ? 52.169 48.836 9.476 1.00 10.78 ? 195 VAL A C 1 ATOM 1429 O O . VAL A 1 195 ? 52.439 49.960 9.039 1.00 10.65 ? 195 VAL A O 1 ATOM 1430 C CB . VAL A 1 195 ? 51.653 48.735 11.929 1.00 12.26 ? 195 VAL A CB 1 ATOM 1431 C CG1 . VAL A 1 195 ? 52.026 48.241 13.329 1.00 18.97 ? 195 VAL A CG1 1 ATOM 1432 C CG2 . VAL A 1 195 ? 51.350 50.211 11.977 1.00 14.31 ? 195 VAL A CG2 1 ATOM 1433 N N . THR A 1 196 ? 51.402 47.949 8.858 1.00 10.30 ? 196 THR A N 1 ATOM 1434 C CA . THR A 1 196 ? 50.693 48.214 7.592 1.00 11.05 ? 196 THR A CA 1 ATOM 1435 C C . THR A 1 196 ? 49.249 47.742 7.794 1.00 11.10 ? 196 THR A C 1 ATOM 1436 O O . THR A 1 196 ? 48.971 46.531 7.869 1.00 11.56 ? 196 THR A O 1 ATOM 1437 C CB . THR A 1 196 ? 51.354 47.472 6.378 1.00 10.04 ? 196 THR A CB 1 ATOM 1438 O OG1 . THR A 1 196 ? 52.707 47.924 6.267 1.00 12.36 ? 196 THR A OG1 1 ATOM 1439 C CG2 . THR A 1 196 ? 50.576 47.813 5.076 1.00 12.89 ? 196 THR A CG2 1 ATOM 1440 N N . PRO A 1 197 ? 48.308 48.676 7.923 1.00 9.00 ? 197 PRO A N 1 ATOM 1441 C CA . PRO A 1 197 ? 46.915 48.301 8.125 1.00 8.74 ? 197 PRO A CA 1 ATOM 1442 C C . PRO A 1 197 ? 46.378 47.439 6.993 1.00 10.06 ? 197 PRO A C 1 ATOM 1443 O O . PRO A 1 197 ? 46.689 47.665 5.815 1.00 9.12 ? 197 PRO A O 1 ATOM 1444 C CB . PRO A 1 197 ? 46.192 49.663 8.117 1.00 9.91 ? 197 PRO A CB 1 ATOM 1445 C CG . PRO A 1 197 ? 47.209 50.605 8.610 1.00 10.01 ? 197 PRO A CG 1 ATOM 1446 C CD . PRO A 1 197 ? 48.516 50.138 8.053 1.00 9.80 ? 197 PRO A CD 1 ATOM 1447 N N . THR A 1 198 ? 45.535 46.470 7.355 1.00 8.83 ? 198 THR A N 1 ATOM 1448 C CA . THR A 1 198 ? 44.825 45.644 6.356 1.00 9.72 ? 198 THR A CA 1 ATOM 1449 C C . THR A 1 198 ? 43.306 45.809 6.458 1.00 7.35 ? 198 THR A C 1 ATOM 1450 O O . THR A 1 198 ? 42.584 45.116 5.711 1.00 8.27 ? 198 THR A O 1 ATOM 1451 C CB . THR A 1 198 ? 45.169 44.148 6.500 1.00 10.92 ? 198 THR A CB 1 ATOM 1452 O OG1 . THR A 1 198 ? 44.750 43.727 7.781 1.00 12.43 ? 198 THR A OG1 1 ATOM 1453 C CG2 . THR A 1 198 ? 46.691 43.899 6.297 1.00 12.28 ? 198 THR A CG2 1 ATOM 1454 N N . ALA A 1 199 ? 42.828 46.681 7.337 1.00 7.68 ? 199 ALA A N 1 ATOM 1455 C CA . ALA A 1 199 ? 41.392 47.001 7.433 1.00 7.75 ? 199 ALA A CA 1 ATOM 1456 C C . ALA A 1 199 ? 41.252 48.489 7.192 1.00 8.37 ? 199 ALA A C 1 ATOM 1457 O O . ALA A 1 199 ? 42.020 49.278 7.765 1.00 8.88 ? 199 ALA A O 1 ATOM 1458 C CB . ALA A 1 199 ? 40.866 46.657 8.868 1.00 9.92 ? 199 ALA A CB 1 ATOM 1459 N N . SER A 1 200 ? 40.273 48.857 6.392 1.00 7.67 ? 200 SER A N 1 ATOM 1460 C CA . SER A 1 200 ? 39.998 50.258 6.065 1.00 7.92 ? 200 SER A CA 1 ATOM 1461 C C . SER A 1 200 ? 38.727 50.741 6.756 1.00 7.64 ? 200 SER A C 1 ATOM 1462 O O . SER A 1 200 ? 37.762 49.983 6.937 1.00 8.97 ? 200 SER A O 1 ATOM 1463 C CB . SER A 1 200 ? 39.858 50.393 4.543 1.00 9.29 ? 200 SER A CB 1 ATOM 1464 O OG . SER A 1 200 ? 39.618 51.776 4.176 1.00 11.09 ? 200 SER A OG 1 ATOM 1465 N N . TRP A 1 201 ? 38.707 52.006 7.123 1.00 7.82 ? 201 TRP A N 1 ATOM 1466 C CA . TRP A 1 201 ? 37.616 52.677 7.831 1.00 7.58 ? 201 TRP A CA 1 ATOM 1467 C C . TRP A 1 201 ? 37.296 53.987 7.096 1.00 8.03 ? 201 TRP A C 1 ATOM 1468 O O . TRP A 1 201 ? 38.135 54.938 7.108 1.00 9.54 ? 201 TRP A O 1 ATOM 1469 C CB . TRP A 1 201 ? 38.134 52.975 9.276 1.00 8.14 ? 201 TRP A CB 1 ATOM 1470 C CG . TRP A 1 201 ? 37.271 53.807 10.202 1.00 9.35 ? 201 TRP A CG 1 ATOM 1471 C CD1 . TRP A 1 201 ? 37.413 55.154 10.508 1.00 9.75 ? 201 TRP A CD1 1 ATOM 1472 C CD2 . TRP A 1 201 ? 36.300 53.303 11.123 1.00 8.43 ? 201 TRP A CD2 1 ATOM 1473 N NE1 . TRP A 1 201 ? 36.608 55.496 11.564 1.00 9.29 ? 201 TRP A NE1 1 ATOM 1474 C CE2 . TRP A 1 201 ? 35.918 54.383 11.970 1.00 9.30 ? 201 TRP A CE2 1 ATOM 1475 C CE3 . TRP A 1 201 ? 35.733 52.049 11.333 1.00 9.69 ? 201 TRP A CE3 1 ATOM 1476 C CZ2 . TRP A 1 201 ? 34.982 54.227 13.030 1.00 10.16 ? 201 TRP A CZ2 1 ATOM 1477 C CZ3 . TRP A 1 201 ? 34.804 51.880 12.386 1.00 11.14 ? 201 TRP A CZ3 1 ATOM 1478 C CH2 . TRP A 1 201 ? 34.452 52.967 13.212 1.00 11.17 ? 201 TRP A CH2 1 ATOM 1479 N N . ALA A 1 202 ? 36.115 54.061 6.497 1.00 8.01 ? 202 ALA A N 1 ATOM 1480 C CA . ALA A 1 202 ? 35.714 55.286 5.744 1.00 8.57 ? 202 ALA A CA 1 ATOM 1481 C C . ALA A 1 202 ? 34.286 55.641 6.145 1.00 8.71 ? 202 ALA A C 1 ATOM 1482 O O . ALA A 1 202 ? 33.309 55.183 5.561 1.00 9.30 ? 202 ALA A O 1 ATOM 1483 C CB . ALA A 1 202 ? 35.861 55.037 4.236 1.00 10.31 ? 202 ALA A CB 1 ATOM 1484 N N . ILE A 1 203 ? 34.197 56.435 7.205 1.00 8.64 ? 203 ILE A N 1 ATOM 1485 C CA . ILE A 1 203 ? 32.879 56.721 7.803 1.00 8.20 ? 203 ILE A CA 1 ATOM 1486 C C . ILE A 1 203 ? 32.237 58.017 7.383 1.00 9.66 ? 203 ILE A C 1 ATOM 1487 O O . ILE A 1 203 ? 31.052 58.232 7.659 1.00 9.75 ? 203 ILE A O 1 ATOM 1488 C CB . ILE A 1 203 ? 32.953 56.662 9.374 1.00 8.80 ? 203 ILE A CB 1 ATOM 1489 C CG1 . ILE A 1 203 ? 34.002 57.648 9.929 1.00 10.24 ? 203 ILE A CG1 1 ATOM 1490 C CG2 . ILE A 1 203 ? 33.259 55.205 9.804 1.00 9.99 ? 203 ILE A CG2 1 ATOM 1491 C CD1 . ILE A 1 203 ? 33.865 57.880 11.426 1.00 10.76 ? 203 ILE A CD1 1 ATOM 1492 N N . ASP A 1 204 ? 32.986 58.888 6.690 1.00 9.17 ? 204 ASP A N 1 ATOM 1493 C CA . ASP A 1 204 ? 32.426 60.168 6.297 1.00 8.85 ? 204 ASP A CA 1 ATOM 1494 C C . ASP A 1 204 ? 32.387 60.580 4.824 1.00 7.95 ? 204 ASP A C 1 ATOM 1495 O O . ASP A 1 204 ? 31.672 61.560 4.556 1.00 10.07 ? 204 ASP A O 1 ATOM 1496 C CB . ASP A 1 204 ? 33.060 61.299 7.107 1.00 10.24 ? 204 ASP A CB 1 ATOM 1497 C CG . ASP A 1 204 ? 32.082 62.441 7.455 1.00 9.86 ? 204 ASP A CG 1 ATOM 1498 O OD1 . ASP A 1 204 ? 32.512 63.636 7.698 1.00 11.42 ? 204 ASP A OD1 1 ATOM 1499 O OD2 . ASP A 1 204 ? 30.864 62.249 7.600 1.00 10.55 ? 204 ASP A OD2 1 ATOM 1500 N N . PRO A 1 205 ? 33.094 59.918 3.859 1.00 7.95 ? 205 PRO A N 1 ATOM 1501 C CA . PRO A 1 205 ? 32.961 60.394 2.441 1.00 8.70 ? 205 PRO A CA 1 ATOM 1502 C C . PRO A 1 205 ? 31.474 60.298 2.043 1.00 8.51 ? 205 PRO A C 1 ATOM 1503 O O . PRO A 1 205 ? 30.690 59.437 2.539 1.00 9.03 ? 205 PRO A O 1 ATOM 1504 C CB . PRO A 1 205 ? 33.799 59.412 1.646 1.00 9.92 ? 205 PRO A CB 1 ATOM 1505 C CG . PRO A 1 205 ? 34.909 58.994 2.649 1.00 13.66 ? 205 PRO A CG 1 ATOM 1506 C CD . PRO A 1 205 ? 34.060 58.800 3.942 1.00 9.51 ? 205 PRO A CD 1 ATOM 1507 N N . PHE A 1 206 ? 31.058 61.174 1.118 1.00 7.65 ? 206 PHE A N 1 ATOM 1508 C CA . PHE A 1 206 ? 29.592 61.317 0.856 1.00 7.80 ? 206 PHE A CA 1 ATOM 1509 C C . PHE A 1 206 ? 29.170 60.404 -0.299 1.00 7.46 ? 206 PHE A C 1 ATOM 1510 O O . PHE A 1 206 ? 28.955 60.803 -1.456 1.00 8.48 ? 206 PHE A O 1 ATOM 1511 C CB . PHE A 1 206 ? 29.294 62.790 0.539 1.00 8.16 ? 206 PHE A CB 1 ATOM 1512 C CG . PHE A 1 206 ? 30.125 63.787 1.378 1.00 7.71 ? 206 PHE A CG 1 ATOM 1513 C CD1 . PHE A 1 206 ? 30.340 63.586 2.717 1.00 8.19 ? 206 PHE A CD1 1 ATOM 1514 C CD2 . PHE A 1 206 ? 30.684 64.916 0.765 1.00 7.81 ? 206 PHE A CD2 1 ATOM 1515 C CE1 . PHE A 1 206 ? 31.130 64.493 3.448 1.00 9.05 ? 206 PHE A CE1 1 ATOM 1516 C CE2 . PHE A 1 206 ? 31.471 65.814 1.508 1.00 7.96 ? 206 PHE A CE2 1 ATOM 1517 C CZ . PHE A 1 206 ? 31.686 65.590 2.846 1.00 8.94 ? 206 PHE A CZ 1 ATOM 1518 N N . GLY A 1 207 ? 29.060 59.126 0.049 1.00 8.32 ? 207 GLY A N 1 ATOM 1519 C CA . GLY A 1 207 ? 28.856 58.061 -0.928 1.00 7.85 ? 207 GLY A CA 1 ATOM 1520 C C . GLY A 1 207 ? 30.180 57.325 -1.166 1.00 7.71 ? 207 GLY A C 1 ATOM 1521 O O . GLY A 1 207 ? 31.246 57.889 -0.831 1.00 8.18 ? 207 GLY A O 1 ATOM 1522 N N . HIS A 1 208 ? 30.135 56.148 -1.759 1.00 7.50 ? 208 HIS A N 1 ATOM 1523 C CA . HIS A 1 208 ? 31.341 55.290 -1.842 1.00 7.35 ? 208 HIS A CA 1 ATOM 1524 C C . HIS A 1 208 ? 31.517 54.678 -3.201 1.00 7.28 ? 208 HIS A C 1 ATOM 1525 O O . HIS A 1 208 ? 30.551 54.352 -3.924 1.00 7.76 ? 208 HIS A O 1 ATOM 1526 C CB . HIS A 1 208 ? 31.211 54.164 -0.765 1.00 7.49 ? 208 HIS A CB 1 ATOM 1527 C CG . HIS A 1 208 ? 31.325 54.684 0.650 1.00 8.06 ? 208 HIS A CG 1 ATOM 1528 N ND1 . HIS A 1 208 ? 32.557 54.915 1.244 1.00 10.40 ? 208 HIS A ND1 1 ATOM 1529 C CD2 . HIS A 1 208 ? 30.380 55.019 1.554 1.00 9.42 ? 208 HIS A CD2 1 ATOM 1530 C CE1 . HIS A 1 208 ? 32.329 55.368 2.479 1.00 10.85 ? 208 HIS A CE1 1 ATOM 1531 N NE2 . HIS A 1 208 ? 31.043 55.443 2.688 1.00 11.33 ? 208 HIS A NE2 1 ATOM 1532 N N . SER A 1 209 ? 32.786 54.536 -3.602 1.00 7.44 ? 209 SER A N 1 ATOM 1533 C CA . SER A 1 209 ? 33.176 54.052 -4.916 1.00 6.60 ? 209 SER A CA 1 ATOM 1534 C C . SER A 1 209 ? 33.894 52.727 -4.864 1.00 7.24 ? 209 SER A C 1 ATOM 1535 O O . SER A 1 209 ? 34.716 52.490 -3.967 1.00 7.34 ? 209 SER A O 1 ATOM 1536 C CB . SER A 1 209 ? 34.154 55.066 -5.515 1.00 7.37 ? 209 SER A CB 1 ATOM 1537 O OG . SER A 1 209 ? 34.665 54.548 -6.736 1.00 7.73 ? 209 SER A OG 1 ATOM 1538 N N . PRO A 1 210 ? 33.652 51.832 -5.835 1.00 6.96 ? 210 PRO A N 1 ATOM 1539 C CA . PRO A 1 210 ? 34.341 50.535 -5.885 1.00 7.89 ? 210 PRO A CA 1 ATOM 1540 C C . PRO A 1 210 ? 35.829 50.745 -6.206 1.00 7.41 ? 210 PRO A C 1 ATOM 1541 O O . PRO A 1 210 ? 36.629 49.772 -6.173 1.00 7.36 ? 210 PRO A O 1 ATOM 1542 C CB . PRO A 1 210 ? 33.601 49.752 -6.964 1.00 8.04 ? 210 PRO A CB 1 ATOM 1543 C CG . PRO A 1 210 ? 33.041 50.863 -7.891 1.00 9.04 ? 210 PRO A CG 1 ATOM 1544 C CD . PRO A 1 210 ? 32.649 51.976 -6.905 1.00 7.26 ? 210 PRO A CD 1 ATOM 1545 N N . THR A 1 211 ? 36.255 51.973 -6.602 1.00 6.95 ? 211 THR A N 1 ATOM 1546 C CA . THR A 1 211 ? 37.694 52.172 -6.779 1.00 7.85 ? 211 THR A CA 1 ATOM 1547 C C . THR A 1 211 ? 38.435 51.913 -5.460 1.00 6.95 ? 211 THR A C 1 ATOM 1548 O O . THR A 1 211 ? 39.621 51.536 -5.510 1.00 7.40 ? 211 THR A O 1 ATOM 1549 C CB . THR A 1 211 ? 37.928 53.618 -7.273 1.00 7.44 ? 211 THR A CB 1 ATOM 1550 O OG1 . THR A 1 211 ? 37.366 53.679 -8.594 1.00 8.35 ? 211 THR A OG1 1 ATOM 1551 C CG2 . THR A 1 211 ? 39.425 53.977 -7.301 1.00 9.15 ? 211 THR A CG2 1 ATOM 1552 N N . MET A 1 212 ? 37.790 52.167 -4.320 1.00 6.99 ? 212 MET A N 1 ATOM 1553 C CA . MET A 1 212 ? 38.482 51.925 -3.058 1.00 7.03 ? 212 MET A CA 1 ATOM 1554 C C . MET A 1 212 ? 38.820 50.435 -2.861 1.00 7.75 ? 212 MET A C 1 ATOM 1555 O O . MET A 1 212 ? 40.012 50.118 -2.653 1.00 8.02 ? 212 MET A O 1 ATOM 1556 C CB . MET A 1 212 ? 37.667 52.496 -1.896 1.00 9.04 ? 212 MET A CB 1 ATOM 1557 C CG . MET A 1 212 ? 37.420 53.999 -1.983 1.00 10.86 ? 212 MET A CG 1 ATOM 1558 S SD . MET A 1 212 ? 38.909 54.965 -2.253 1.00 14.79 ? 212 MET A SD 1 ATOM 1559 C CE . MET A 1 212 ? 39.614 54.938 -0.803 1.00 15.92 ? 212 MET A CE 1 ATOM 1560 N N . PRO A 1 213 ? 37.848 49.498 -2.899 1.00 7.46 ? 213 PRO A N 1 ATOM 1561 C CA . PRO A 1 213 ? 38.281 48.094 -2.739 1.00 6.54 ? 213 PRO A CA 1 ATOM 1562 C C . PRO A 1 213 ? 39.249 47.708 -3.855 1.00 7.80 ? 213 PRO A C 1 ATOM 1563 O O . PRO A 1 213 ? 40.146 46.840 -3.614 1.00 8.16 ? 213 PRO A O 1 ATOM 1564 C CB . PRO A 1 213 ? 36.966 47.277 -2.775 1.00 8.63 ? 213 PRO A CB 1 ATOM 1565 C CG . PRO A 1 213 ? 35.955 48.240 -3.422 1.00 8.53 ? 213 PRO A CG 1 ATOM 1566 C CD . PRO A 1 213 ? 36.379 49.608 -2.863 1.00 7.77 ? 213 PRO A CD 1 ATOM 1567 N N . TYR A 1 214 ? 39.126 48.265 -5.072 1.00 7.31 ? 214 TYR A N 1 ATOM 1568 C CA . TYR A 1 214 ? 40.073 47.909 -6.137 1.00 7.94 ? 214 TYR A CA 1 ATOM 1569 C C . TYR A 1 214 ? 41.520 48.198 -5.677 1.00 9.37 ? 214 TYR A C 1 ATOM 1570 O O . TYR A 1 214 ? 42.408 47.299 -5.763 1.00 9.07 ? 214 TYR A O 1 ATOM 1571 C CB . TYR A 1 214 ? 39.792 48.732 -7.399 1.00 8.12 ? 214 TYR A CB 1 ATOM 1572 C CG . TYR A 1 214 ? 40.742 48.473 -8.512 1.00 9.45 ? 214 TYR A CG 1 ATOM 1573 C CD1 . TYR A 1 214 ? 40.519 47.389 -9.374 1.00 14.23 ? 214 TYR A CD1 1 ATOM 1574 C CD2 . TYR A 1 214 ? 41.808 49.309 -8.784 1.00 8.50 ? 214 TYR A CD2 1 ATOM 1575 C CE1 . TYR A 1 214 ? 41.332 47.170 -10.512 1.00 15.00 ? 214 TYR A CE1 1 ATOM 1576 C CE2 . TYR A 1 214 ? 42.649 49.129 -9.898 1.00 9.55 ? 214 TYR A CE2 1 ATOM 1577 C CZ . TYR A 1 214 ? 42.366 48.065 -10.745 1.00 12.77 ? 214 TYR A CZ 1 ATOM 1578 O OH . TYR A 1 214 ? 43.113 47.945 -11.914 1.00 13.92 ? 214 TYR A OH 1 ATOM 1579 N N . ILE A 1 215 ? 41.783 49.438 -5.220 1.00 7.07 ? 215 ILE A N 1 ATOM 1580 C CA . ILE A 1 215 ? 43.127 49.814 -4.788 1.00 7.03 ? 215 ILE A CA 1 ATOM 1581 C C . ILE A 1 215 ? 43.530 49.073 -3.507 1.00 8.21 ? 215 ILE A C 1 ATOM 1582 O O . ILE A 1 215 ? 44.662 48.576 -3.380 1.00 7.81 ? 215 ILE A O 1 ATOM 1583 C CB . ILE A 1 215 ? 43.183 51.333 -4.595 1.00 7.44 ? 215 ILE A CB 1 ATOM 1584 C CG1 . ILE A 1 215 ? 43.074 52.050 -5.928 1.00 9.16 ? 215 ILE A CG1 1 ATOM 1585 C CG2 . ILE A 1 215 ? 44.524 51.736 -3.868 1.00 9.13 ? 215 ILE A CG2 1 ATOM 1586 C CD1 . ILE A 1 215 ? 42.885 53.583 -5.748 1.00 11.99 ? 215 ILE A CD1 1 ATOM 1587 N N . LEU A 1 216 ? 42.612 49.006 -2.561 1.00 6.68 ? 216 LEU A N 1 ATOM 1588 C CA . LEU A 1 216 ? 42.921 48.388 -1.260 1.00 7.04 ? 216 LEU A CA 1 ATOM 1589 C C . LEU A 1 216 ? 43.256 46.906 -1.402 1.00 7.74 ? 216 LEU A C 1 ATOM 1590 O O . LEU A 1 216 ? 44.265 46.458 -0.792 1.00 8.15 ? 216 LEU A O 1 ATOM 1591 C CB . LEU A 1 216 ? 41.742 48.554 -0.298 1.00 6.63 ? 216 LEU A CB 1 ATOM 1592 C CG . LEU A 1 216 ? 41.365 49.993 0.104 1.00 7.81 ? 216 LEU A CG 1 ATOM 1593 C CD1 . LEU A 1 216 ? 40.056 49.970 0.878 1.00 9.37 ? 216 LEU A CD1 1 ATOM 1594 C CD2 . LEU A 1 216 ? 42.522 50.651 0.951 1.00 9.62 ? 216 LEU A CD2 1 ATOM 1595 N N . GLN A 1 217 ? 42.496 46.165 -2.209 1.00 7.61 ? 217 GLN A N 1 ATOM 1596 C CA . GLN A 1 217 ? 42.769 44.737 -2.364 1.00 8.23 ? 217 GLN A CA 1 ATOM 1597 C C . GLN A 1 217 ? 44.140 44.530 -3.038 1.00 8.69 ? 217 GLN A C 1 ATOM 1598 O O . GLN A 1 217 ? 44.792 43.505 -2.769 1.00 10.94 ? 217 GLN A O 1 ATOM 1599 C CB . GLN A 1 217 ? 41.576 44.126 -3.097 1.00 10.83 ? 217 GLN A CB 1 ATOM 1600 C CG . GLN A 1 217 ? 41.632 42.563 -3.196 1.00 10.45 ? 217 GLN A CG 1 ATOM 1601 C CD . GLN A 1 217 ? 42.497 42.041 -4.303 1.00 14.73 ? 217 GLN A CD 1 ATOM 1602 O OE1 . GLN A 1 217 ? 42.608 42.656 -5.361 1.00 15.24 ? 217 GLN A OE1 1 ATOM 1603 N NE2 . GLN A 1 217 ? 43.089 40.851 -4.089 1.00 17.82 ? 217 GLN A NE2 1 ATOM 1604 N N . LYS A 1 218 ? 44.609 45.450 -3.872 1.00 7.98 ? 218 LYS A N 1 ATOM 1605 C CA . LYS A 1 218 ? 45.922 45.341 -4.529 1.00 7.84 ? 218 LYS A CA 1 ATOM 1606 C C . LYS A 1 218 ? 47.026 45.960 -3.643 1.00 9.00 ? 218 LYS A C 1 ATOM 1607 O O . LYS A 1 218 ? 48.193 46.051 -4.066 1.00 9.04 ? 218 LYS A O 1 ATOM 1608 C CB . LYS A 1 218 ? 45.852 46.075 -5.879 1.00 8.44 ? 218 LYS A CB 1 ATOM 1609 C CG . LYS A 1 218 ? 45.094 45.248 -6.892 1.00 9.95 ? 218 LYS A CG 1 ATOM 1610 C CD . LYS A 1 218 ? 44.792 46.110 -8.177 1.00 9.31 ? 218 LYS A CD 1 ATOM 1611 C CE . LYS A 1 218 ? 44.360 45.271 -9.349 1.00 13.70 ? 218 LYS A CE 1 ATOM 1612 N NZ . LYS A 1 218 ? 43.259 44.311 -9.127 1.00 14.32 ? 218 LYS A NZ 1 ATOM 1613 N N . SER A 1 219 ? 46.660 46.400 -2.445 1.00 7.44 ? 219 SER A N 1 ATOM 1614 C CA . SER A 1 219 ? 47.561 46.996 -1.473 1.00 8.58 ? 219 SER A CA 1 ATOM 1615 C C . SER A 1 219 ? 47.595 46.197 -0.140 1.00 8.07 ? 219 SER A C 1 ATOM 1616 O O . SER A 1 219 ? 47.918 46.751 0.914 1.00 8.87 ? 219 SER A O 1 ATOM 1617 C CB . SER A 1 219 ? 47.194 48.466 -1.189 1.00 8.04 ? 219 SER A CB 1 ATOM 1618 O OG . SER A 1 219 ? 47.243 49.202 -2.442 1.00 9.59 ? 219 SER A OG 1 ATOM 1619 N N . GLY A 1 220 ? 47.247 44.913 -0.225 1.00 8.69 ? 220 GLY A N 1 ATOM 1620 C CA . GLY A 1 220 ? 47.319 44.033 0.957 1.00 9.55 ? 220 GLY A CA 1 ATOM 1621 C C . GLY A 1 220 ? 46.098 44.004 1.854 1.00 9.14 ? 220 GLY A C 1 ATOM 1622 O O . GLY A 1 220 ? 46.089 43.207 2.807 1.00 10.37 ? 220 GLY A O 1 ATOM 1623 N N . PHE A 1 221 ? 45.040 44.773 1.579 1.00 9.18 ? 221 PHE A N 1 ATOM 1624 C CA . PHE A 1 221 ? 43.920 44.787 2.516 1.00 8.08 ? 221 PHE A CA 1 ATOM 1625 C C . PHE A 1 221 ? 43.085 43.525 2.428 1.00 8.10 ? 221 PHE A C 1 ATOM 1626 O O . PHE A 1 221 ? 42.979 42.876 1.370 1.00 9.08 ? 221 PHE A O 1 ATOM 1627 C CB . PHE A 1 221 ? 43.026 46.007 2.251 1.00 7.53 ? 221 PHE A CB 1 ATOM 1628 C CG . PHE A 1 221 ? 43.587 47.295 2.771 1.00 7.56 ? 221 PHE A CG 1 ATOM 1629 C CD1 . PHE A 1 221 ? 44.720 47.906 2.190 1.00 7.69 ? 221 PHE A CD1 1 ATOM 1630 C CD2 . PHE A 1 221 ? 43.009 47.910 3.896 1.00 7.51 ? 221 PHE A CD2 1 ATOM 1631 C CE1 . PHE A 1 221 ? 45.237 49.083 2.732 1.00 7.25 ? 221 PHE A CE1 1 ATOM 1632 C CE2 . PHE A 1 221 ? 43.526 49.079 4.423 1.00 8.23 ? 221 PHE A CE2 1 ATOM 1633 C CZ . PHE A 1 221 ? 44.650 49.693 3.834 1.00 7.58 ? 221 PHE A CZ 1 ATOM 1634 N N A LYS A 1 222 ? 42.421 43.268 3.559 0.50 9.66 ? 222 LYS A N 1 ATOM 1635 N N B LYS A 1 222 ? 42.421 43.268 3.559 0.50 9.78 ? 222 LYS A N 1 ATOM 1636 C CA A LYS A 1 222 ? 41.515 42.148 3.712 0.50 9.50 ? 222 LYS A CA 1 ATOM 1637 C CA B LYS A 1 222 ? 41.515 42.148 3.712 0.50 9.76 ? 222 LYS A CA 1 ATOM 1638 C C A LYS A 1 222 ? 40.115 42.558 4.055 0.50 9.03 ? 222 LYS A C 1 ATOM 1639 C C B LYS A 1 222 ? 40.115 42.558 4.055 0.50 9.20 ? 222 LYS A C 1 ATOM 1640 O O A LYS A 1 222 ? 39.202 41.755 3.839 0.50 9.54 ? 222 LYS A O 1 ATOM 1641 O O B LYS A 1 222 ? 39.202 41.755 3.839 0.50 9.66 ? 222 LYS A O 1 ATOM 1642 C CB A LYS A 1 222 ? 42.016 41.179 4.797 0.50 13.48 ? 222 LYS A CB 1 ATOM 1643 C CB B LYS A 1 222 ? 42.016 41.179 4.797 0.50 13.98 ? 222 LYS A CB 1 ATOM 1644 C CG A LYS A 1 222 ? 43.401 40.627 4.510 0.50 15.55 ? 222 LYS A CG 1 ATOM 1645 C CG B LYS A 1 222 ? 43.401 40.627 4.510 0.50 16.57 ? 222 LYS A CG 1 ATOM 1646 C CD A LYS A 1 222 ? 43.505 40.008 3.148 0.50 22.62 ? 222 LYS A CD 1 ATOM 1647 C CD B LYS A 1 222 ? 43.505 40.008 3.148 0.50 23.52 ? 222 LYS A CD 1 ATOM 1648 C CE A LYS A 1 222 ? 44.913 39.444 2.889 0.50 30.46 ? 222 LYS A CE 1 ATOM 1649 C CE B LYS A 1 222 ? 44.913 39.444 2.889 0.50 30.93 ? 222 LYS A CE 1 ATOM 1650 N NZ A LYS A 1 222 ? 45.288 38.633 4.085 0.50 34.11 ? 222 LYS A NZ 1 ATOM 1651 N NZ B LYS A 1 222 ? 45.834 40.610 2.747 0.50 35.32 ? 222 LYS A NZ 1 ATOM 1652 N N . ASN A 1 223 ? 39.903 43.779 4.534 1.00 7.27 ? 223 ASN A N 1 ATOM 1653 C CA . ASN A 1 223 ? 38.551 44.176 4.956 1.00 8.73 ? 223 ASN A CA 1 ATOM 1654 C C . ASN A 1 223 ? 38.397 45.672 4.830 1.00 8.17 ? 223 ASN A C 1 ATOM 1655 O O . ASN A 1 223 ? 39.390 46.417 4.951 1.00 7.83 ? 223 ASN A O 1 ATOM 1656 C CB . ASN A 1 223 ? 38.335 43.835 6.479 1.00 8.23 ? 223 ASN A CB 1 ATOM 1657 C CG . ASN A 1 223 ? 38.427 42.333 6.761 1.00 10.24 ? 223 ASN A CG 1 ATOM 1658 O OD1 . ASN A 1 223 ? 39.499 41.830 7.227 1.00 13.62 ? 223 ASN A OD1 1 ATOM 1659 N ND2 . ASN A 1 223 ? 37.396 41.638 6.453 1.00 7.87 ? 223 ASN A ND2 1 ATOM 1660 N N . MET A 1 224 ? 37.156 46.117 4.690 1.00 7.34 ? 224 MET A N 1 ATOM 1661 C CA . MET A 1 224 ? 36.881 47.574 4.690 1.00 6.65 ? 224 MET A CA 1 ATOM 1662 C C . MET A 1 224 ? 35.500 47.874 5.245 1.00 7.72 ? 224 MET A C 1 ATOM 1663 O O . MET A 1 224 ? 34.602 46.979 5.223 1.00 8.83 ? 224 MET A O 1 ATOM 1664 C CB . MET A 1 224 ? 37.050 48.178 3.281 1.00 8.88 ? 224 MET A CB 1 ATOM 1665 C CG . MET A 1 224 ? 36.046 47.590 2.256 1.00 8.47 ? 224 MET A CG 1 ATOM 1666 S SD . MET A 1 224 ? 36.178 48.415 0.616 1.00 10.34 ? 224 MET A SD 1 ATOM 1667 C CE . MET A 1 224 ? 35.851 49.994 0.986 1.00 14.46 ? 224 MET A CE 1 ATOM 1668 N N . LEU A 1 225 ? 35.322 49.096 5.707 1.00 7.33 ? 225 LEU A N 1 ATOM 1669 C CA . LEU A 1 225 ? 34.061 49.522 6.286 1.00 7.58 ? 225 LEU A CA 1 ATOM 1670 C C . LEU A 1 225 ? 33.638 50.838 5.664 1.00 8.05 ? 225 LEU A C 1 ATOM 1671 O O . LEU A 1 225 ? 34.496 51.734 5.471 1.00 8.30 ? 225 LEU A O 1 ATOM 1672 C CB . LEU A 1 225 ? 34.261 49.625 7.799 1.00 8.28 ? 225 LEU A CB 1 ATOM 1673 C CG . LEU A 1 225 ? 33.025 50.220 8.549 1.00 8.44 ? 225 LEU A CG 1 ATOM 1674 C CD1 . LEU A 1 225 ? 32.922 49.580 9.959 1.00 9.13 ? 225 LEU A CD1 1 ATOM 1675 C CD2 . LEU A 1 225 ? 33.071 51.744 8.614 1.00 8.67 ? 225 LEU A CD2 1 ATOM 1676 N N . ILE A 1 226 ? 32.353 50.960 5.371 1.00 7.47 ? 226 ILE A N 1 ATOM 1677 C CA . ILE A 1 226 ? 31.754 52.195 4.802 1.00 8.43 ? 226 ILE A CA 1 ATOM 1678 C C . ILE A 1 226 ? 30.514 52.557 5.575 1.00 7.83 ? 226 ILE A C 1 ATOM 1679 O O . ILE A 1 226 ? 29.942 51.721 6.304 1.00 8.49 ? 226 ILE A O 1 ATOM 1680 C CB . ILE A 1 226 ? 31.449 51.996 3.280 1.00 8.42 ? 226 ILE A CB 1 ATOM 1681 C CG1 . ILE A 1 226 ? 30.419 50.869 3.053 1.00 8.73 ? 226 ILE A CG1 1 ATOM 1682 C CG2 . ILE A 1 226 ? 32.781 51.695 2.524 1.00 9.59 ? 226 ILE A CG2 1 ATOM 1683 C CD1 . ILE A 1 226 ? 30.055 50.730 1.565 1.00 10.23 ? 226 ILE A CD1 1 ATOM 1684 N N . GLN A 1 227 ? 30.099 53.805 5.449 1.00 9.06 ? 227 GLN A N 1 ATOM 1685 C CA . GLN A 1 227 ? 28.931 54.333 6.197 1.00 9.47 ? 227 GLN A CA 1 ATOM 1686 C C . GLN A 1 227 ? 27.947 55.151 5.380 1.00 9.51 ? 227 GLN A C 1 ATOM 1687 O O . GLN A 1 227 ? 26.730 54.889 5.484 1.00 10.16 ? 227 GLN A O 1 ATOM 1688 C CB . GLN A 1 227 ? 29.442 55.186 7.369 1.00 9.62 ? 227 GLN A CB 1 ATOM 1689 C CG . GLN A 1 227 ? 28.451 56.246 7.991 1.00 12.71 ? 227 GLN A CG 1 ATOM 1690 C CD . GLN A 1 227 ? 27.092 55.731 8.447 1.00 11.03 ? 227 GLN A CD 1 ATOM 1691 O OE1 . GLN A 1 227 ? 26.946 54.529 8.719 1.00 13.72 ? 227 GLN A OE1 1 ATOM 1692 N NE2 . GLN A 1 227 ? 26.110 56.621 8.554 1.00 12.05 ? 227 GLN A NE2 1 ATOM 1693 N N . ARG A 1 228 ? 28.359 56.138 4.601 1.00 8.51 ? 228 ARG A N 1 ATOM 1694 C CA . ARG A 1 228 ? 27.362 56.982 3.973 1.00 9.16 ? 228 ARG A CA 1 ATOM 1695 C C . ARG A 1 228 ? 26.874 56.439 2.689 1.00 9.33 ? 228 ARG A C 1 ATOM 1696 O O . ARG A 1 228 ? 27.442 56.707 1.630 1.00 10.25 ? 228 ARG A O 1 ATOM 1697 C CB . ARG A 1 228 ? 27.937 58.432 3.800 1.00 9.57 ? 228 ARG A CB 1 ATOM 1698 C CG . ARG A 1 228 ? 28.118 59.182 5.074 1.00 8.85 ? 228 ARG A CG 1 ATOM 1699 C CD . ARG A 1 228 ? 28.416 60.661 4.747 1.00 10.10 ? 228 ARG A CD 1 ATOM 1700 N NE . ARG A 1 228 ? 28.678 61.532 5.908 1.00 9.80 ? 228 ARG A NE 1 ATOM 1701 C CZ . ARG A 1 228 ? 27.742 62.236 6.537 1.00 10.63 ? 228 ARG A CZ 1 ATOM 1702 N NH1 . ARG A 1 228 ? 26.473 62.107 6.170 1.00 11.57 ? 228 ARG A NH1 1 ATOM 1703 N NH2 . ARG A 1 228 ? 28.103 63.156 7.438 1.00 12.87 ? 228 ARG A NH2 1 ATOM 1704 N N . THR A 1 229 ? 25.785 55.670 2.776 1.00 9.88 ? 229 THR A N 1 ATOM 1705 C CA . THR A 1 229 ? 25.098 55.139 1.613 1.00 8.39 ? 229 THR A CA 1 ATOM 1706 C C . THR A 1 229 ? 23.625 55.554 1.800 1.00 8.26 ? 229 THR A C 1 ATOM 1707 O O . THR A 1 229 ? 23.132 55.818 2.911 1.00 9.83 ? 229 THR A O 1 ATOM 1708 C CB . THR A 1 229 ? 25.252 53.602 1.501 1.00 10.11 ? 229 THR A CB 1 ATOM 1709 O OG1 . THR A 1 229 ? 24.612 53.017 2.643 1.00 10.64 ? 229 THR A OG1 1 ATOM 1710 C CG2 . THR A 1 229 ? 26.719 53.200 1.446 1.00 9.68 ? 229 THR A CG2 1 ATOM 1711 N N . HIS A 1 230 ? 22.949 55.597 0.662 1.00 8.34 ? 230 HIS A N 1 ATOM 1712 C CA . HIS A 1 230 ? 21.556 56.054 0.657 1.00 9.70 ? 230 HIS A CA 1 ATOM 1713 C C . HIS A 1 230 ? 20.720 55.303 1.689 1.00 8.89 ? 230 HIS A C 1 ATOM 1714 O O . HIS A 1 230 ? 20.793 54.064 1.790 1.00 9.71 ? 230 HIS A O 1 ATOM 1715 C CB . HIS A 1 230 ? 21.012 55.803 -0.752 1.00 9.12 ? 230 HIS A CB 1 ATOM 1716 C CG . HIS A 1 230 ? 19.709 56.487 -1.087 1.00 9.98 ? 230 HIS A CG 1 ATOM 1717 N ND1 . HIS A 1 230 ? 18.519 56.209 -0.417 1.00 10.52 ? 230 HIS A ND1 1 ATOM 1718 C CD2 . HIS A 1 230 ? 19.407 57.390 -2.051 1.00 11.86 ? 230 HIS A CD2 1 ATOM 1719 C CE1 . HIS A 1 230 ? 17.546 56.938 -0.948 1.00 11.02 ? 230 HIS A CE1 1 ATOM 1720 N NE2 . HIS A 1 230 ? 18.049 57.653 -1.945 1.00 10.88 ? 230 HIS A NE2 1 ATOM 1721 N N . TYR A 1 231 ? 19.894 56.046 2.422 1.00 10.18 ? 231 TYR A N 1 ATOM 1722 C CA . TYR A 1 231 ? 19.074 55.385 3.445 1.00 9.82 ? 231 TYR A CA 1 ATOM 1723 C C . TYR A 1 231 ? 18.194 54.276 2.886 1.00 11.06 ? 231 TYR A C 1 ATOM 1724 O O . TYR A 1 231 ? 17.917 53.311 3.621 1.00 11.42 ? 231 TYR A O 1 ATOM 1725 C CB . TYR A 1 231 ? 18.221 56.404 4.218 1.00 11.11 ? 231 TYR A CB 1 ATOM 1726 C CG . TYR A 1 231 ? 17.236 57.194 3.347 1.00 12.01 ? 231 TYR A CG 1 ATOM 1727 C CD1 . TYR A 1 231 ? 15.909 56.716 3.151 1.00 12.22 ? 231 TYR A CD1 1 ATOM 1728 C CD2 . TYR A 1 231 ? 17.605 58.419 2.737 1.00 10.92 ? 231 TYR A CD2 1 ATOM 1729 C CE1 . TYR A 1 231 ? 15.007 57.438 2.379 1.00 13.03 ? 231 TYR A CE1 1 ATOM 1730 C CE2 . TYR A 1 231 ? 16.678 59.164 1.986 1.00 11.28 ? 231 TYR A CE2 1 ATOM 1731 C CZ . TYR A 1 231 ? 15.376 58.648 1.809 1.00 11.90 ? 231 TYR A CZ 1 ATOM 1732 O OH . TYR A 1 231 ? 14.460 59.389 1.048 1.00 13.33 ? 231 TYR A OH 1 ATOM 1733 N N . SER A 1 232 ? 17.733 54.356 1.662 1.00 10.45 ? 232 SER A N 1 ATOM 1734 C CA . SER A 1 232 ? 16.904 53.262 1.111 1.00 11.25 ? 232 SER A CA 1 ATOM 1735 C C . SER A 1 232 ? 17.729 52.047 0.871 1.00 11.38 ? 232 SER A C 1 ATOM 1736 O O . SER A 1 232 ? 17.235 50.895 0.976 1.00 11.70 ? 232 SER A O 1 ATOM 1737 C CB . SER A 1 232 ? 16.242 53.648 -0.210 1.00 12.48 ? 232 SER A CB 1 ATOM 1738 O OG . SER A 1 232 ? 15.327 54.745 -0.041 1.00 15.27 ? 232 SER A OG 1 ATOM 1739 N N . VAL A 1 233 ? 19.003 52.225 0.473 1.00 10.52 ? 233 VAL A N 1 ATOM 1740 C CA . VAL A 1 233 ? 19.907 51.093 0.269 1.00 11.15 ? 233 VAL A CA 1 ATOM 1741 C C . VAL A 1 233 ? 20.178 50.395 1.632 1.00 9.71 ? 233 VAL A C 1 ATOM 1742 O O . VAL A 1 233 ? 20.177 49.141 1.720 1.00 10.90 ? 233 VAL A O 1 ATOM 1743 C CB . VAL A 1 233 ? 21.243 51.577 -0.390 1.00 11.03 ? 233 VAL A CB 1 ATOM 1744 C CG1 . VAL A 1 233 ? 22.272 50.443 -0.394 1.00 11.16 ? 233 VAL A CG1 1 ATOM 1745 C CG2 . VAL A 1 233 ? 20.939 51.944 -1.855 1.00 12.96 ? 233 VAL A CG2 1 ATOM 1746 N N . LYS A 1 234 ? 20.484 51.163 2.667 1.00 9.49 ? 234 LYS A N 1 ATOM 1747 C CA . LYS A 1 234 ? 20.676 50.537 3.999 1.00 9.99 ? 234 LYS A CA 1 ATOM 1748 C C . LYS A 1 234 ? 19.428 49.702 4.376 1.00 9.83 ? 234 LYS A C 1 ATOM 1749 O O . LYS A 1 234 ? 19.609 48.599 4.854 1.00 10.35 ? 234 LYS A O 1 ATOM 1750 C CB . LYS A 1 234 ? 20.870 51.629 5.047 1.00 9.02 ? 234 LYS A CB 1 ATOM 1751 C CG . LYS A 1 234 ? 22.286 52.322 4.951 1.00 11.58 ? 234 LYS A CG 1 ATOM 1752 C CD . LYS A 1 234 ? 22.256 53.601 5.725 1.00 11.38 ? 234 LYS A CD 1 ATOM 1753 C CE . LYS A 1 234 ? 23.712 54.252 5.718 1.00 9.58 ? 234 LYS A CE 1 ATOM 1754 N NZ . LYS A 1 234 ? 24.610 53.719 6.836 1.00 9.77 ? 234 LYS A NZ 1 ATOM 1755 N N . LYS A 1 235 ? 18.224 50.239 4.151 1.00 10.51 ? 235 LYS A N 1 ATOM 1756 C CA . LYS A 1 235 ? 17.031 49.461 4.524 1.00 12.54 ? 235 LYS A CA 1 ATOM 1757 C C . LYS A 1 235 ? 16.903 48.209 3.743 1.00 11.03 ? 235 LYS A C 1 ATOM 1758 O O . LYS A 1 235 ? 16.651 47.116 4.342 1.00 12.01 ? 235 LYS A O 1 ATOM 1759 C CB . LYS A 1 235 ? 15.850 50.353 4.343 1.00 12.01 ? 235 LYS A CB 1 ATOM 1760 C CG . LYS A 1 235 ? 14.468 49.653 4.771 1.00 12.79 ? 235 LYS A CG 1 ATOM 1761 C CD . LYS A 1 235 ? 13.322 50.626 4.712 1.00 14.71 ? 235 LYS A CD 1 ATOM 1762 C CE . LYS A 1 235 ? 12.005 49.949 5.153 1.00 16.80 ? 235 LYS A CE 1 ATOM 1763 N NZ . LYS A 1 235 ? 10.852 50.919 4.933 1.00 23.23 ? 235 LYS A NZ 1 ATOM 1764 N N . GLU A 1 236 ? 17.102 48.264 2.436 1.00 10.62 ? 236 GLU A N 1 ATOM 1765 C CA . GLU A 1 236 ? 16.985 47.081 1.595 1.00 11.33 ? 236 GLU A CA 1 ATOM 1766 C C . GLU A 1 236 ? 18.018 46.011 1.936 1.00 13.65 ? 236 GLU A C 1 ATOM 1767 O O . GLU A 1 236 ? 17.739 44.815 2.057 1.00 14.26 ? 236 GLU A O 1 ATOM 1768 C CB . GLU A 1 236 ? 17.147 47.510 0.130 1.00 15.09 ? 236 GLU A CB 1 ATOM 1769 C CG . GLU A 1 236 ? 17.005 46.418 -0.929 1.00 22.33 ? 236 GLU A CG 1 ATOM 1770 C CD . GLU A 1 236 ? 15.528 46.027 -1.174 1.00 30.83 ? 236 GLU A CD 1 ATOM 1771 O OE1 . GLU A 1 236 ? 15.306 45.019 -1.861 1.00 34.52 ? 236 GLU A OE1 1 ATOM 1772 O OE2 . GLU A 1 236 ? 14.601 46.736 -0.706 1.00 30.90 ? 236 GLU A OE2 1 ATOM 1773 N N . LEU A 1 237 ? 19.286 46.409 2.056 1.00 10.91 ? 237 LEU A N 1 ATOM 1774 C CA . LEU A 1 237 ? 20.301 45.447 2.366 1.00 11.30 ? 237 LEU A CA 1 ATOM 1775 C C . LEU A 1 237 ? 20.096 44.934 3.806 1.00 10.67 ? 237 LEU A C 1 ATOM 1776 O O . LEU A 1 237 ? 20.343 43.727 4.055 1.00 12.64 ? 237 LEU A O 1 ATOM 1777 C CB . LEU A 1 237 ? 21.709 46.042 2.236 1.00 11.12 ? 237 LEU A CB 1 ATOM 1778 C CG . LEU A 1 237 ? 22.053 46.487 0.783 1.00 10.53 ? 237 LEU A CG 1 ATOM 1779 C CD1 . LEU A 1 237 ? 23.523 47.045 0.737 1.00 12.81 ? 237 LEU A CD1 1 ATOM 1780 C CD2 . LEU A 1 237 ? 21.977 45.321 -0.251 1.00 14.11 ? 237 LEU A CD2 1 ATOM 1781 N N . ALA A 1 238 ? 19.681 45.769 4.734 1.00 11.09 ? 238 ALA A N 1 ATOM 1782 C CA . ALA A 1 238 ? 19.482 45.265 6.103 1.00 11.12 ? 238 ALA A CA 1 ATOM 1783 C C . ALA A 1 238 ? 18.398 44.165 6.124 1.00 12.97 ? 238 ALA A C 1 ATOM 1784 O O . ALA A 1 238 ? 18.579 43.152 6.829 1.00 13.81 ? 238 ALA A O 1 ATOM 1785 C CB . ALA A 1 238 ? 19.075 46.385 7.000 1.00 11.79 ? 238 ALA A CB 1 ATOM 1786 N N . GLN A 1 239 ? 17.344 44.353 5.344 1.00 12.82 ? 239 GLN A N 1 ATOM 1787 C CA . GLN A 1 239 ? 16.237 43.366 5.338 1.00 13.46 ? 239 GLN A CA 1 ATOM 1788 C C . GLN A 1 239 ? 16.711 42.011 4.860 1.00 15.79 ? 239 GLN A C 1 ATOM 1789 O O . GLN A 1 239 ? 16.130 40.989 5.247 1.00 17.89 ? 239 GLN A O 1 ATOM 1790 C CB . GLN A 1 239 ? 15.122 43.888 4.438 1.00 16.54 ? 239 GLN A CB 1 ATOM 1791 C CG . GLN A 1 239 ? 14.315 44.991 5.102 1.00 21.43 ? 239 GLN A CG 1 ATOM 1792 C CD . GLN A 1 239 ? 13.289 45.667 4.187 1.00 26.45 ? 239 GLN A CD 1 ATOM 1793 O OE1 . GLN A 1 239 ? 13.414 45.669 2.966 1.00 31.33 ? 239 GLN A OE1 1 ATOM 1794 N NE2 . GLN A 1 239 ? 12.272 46.273 4.801 1.00 31.13 ? 239 GLN A NE2 1 ATOM 1795 N N . GLN A 1 240 ? 17.721 41.951 4.009 1.00 12.49 ? 240 GLN A N 1 ATOM 1796 C CA . GLN A 1 240 ? 18.235 40.693 3.490 1.00 13.05 ? 240 GLN A CA 1 ATOM 1797 C C . GLN A 1 240 ? 19.541 40.274 4.147 1.00 11.16 ? 240 GLN A C 1 ATOM 1798 O O . GLN A 1 240 ? 20.149 39.313 3.723 1.00 12.76 ? 240 GLN A O 1 ATOM 1799 C CB . GLN A 1 240 ? 18.499 40.830 1.971 1.00 16.29 ? 240 GLN A CB 1 ATOM 1800 C CG . GLN A 1 240 ? 17.334 41.407 1.179 1.00 20.49 ? 240 GLN A CG 1 ATOM 1801 C CD . GLN A 1 240 ? 16.134 40.510 1.288 1.00 23.23 ? 240 GLN A CD 1 ATOM 1802 O OE1 . GLN A 1 240 ? 15.015 41.000 1.410 1.00 31.18 ? 240 GLN A OE1 1 ATOM 1803 N NE2 . GLN A 1 240 ? 16.358 39.199 1.274 1.00 23.40 ? 240 GLN A NE2 1 ATOM 1804 N N . ARG A 1 241 ? 19.949 40.986 5.217 1.00 11.90 ? 241 ARG A N 1 ATOM 1805 C CA . ARG A 1 241 ? 21.257 40.735 5.868 1.00 11.36 ? 241 ARG A CA 1 ATOM 1806 C C . ARG A 1 241 ? 22.381 40.710 4.846 1.00 10.60 ? 241 ARG A C 1 ATOM 1807 O O . ARG A 1 241 ? 23.217 39.811 4.778 1.00 11.34 ? 241 ARG A O 1 ATOM 1808 C CB . ARG A 1 241 ? 21.248 39.452 6.712 1.00 12.93 ? 241 ARG A CB 1 ATOM 1809 C CG . ARG A 1 241 ? 20.202 39.588 7.840 1.00 14.86 ? 241 ARG A CG 1 ATOM 1810 C CD . ARG A 1 241 ? 20.248 38.409 8.802 1.00 17.37 ? 241 ARG A CD 1 ATOM 1811 N NE . ARG A 1 241 ? 20.299 37.117 8.150 1.00 24.23 ? 241 ARG A NE 1 ATOM 1812 C CZ . ARG A 1 241 ? 20.731 35.999 8.759 1.00 25.53 ? 241 ARG A CZ 1 ATOM 1813 N NH1 . ARG A 1 241 ? 21.131 36.025 10.032 1.00 25.18 ? 241 ARG A NH1 1 ATOM 1814 N NH2 . ARG A 1 241 ? 20.835 34.862 8.068 1.00 28.05 ? 241 ARG A NH2 1 ATOM 1815 N N . GLN A 1 242 ? 22.368 41.755 3.987 1.00 10.54 ? 242 GLN A N 1 ATOM 1816 C CA . GLN A 1 242 ? 23.404 41.921 2.934 1.00 9.92 ? 242 GLN A CA 1 ATOM 1817 C C . GLN A 1 242 ? 24.242 43.171 3.203 1.00 9.95 ? 242 GLN A C 1 ATOM 1818 O O . GLN A 1 242 ? 24.786 43.735 2.233 1.00 11.77 ? 242 GLN A O 1 ATOM 1819 C CB . GLN A 1 242 ? 22.781 41.971 1.525 1.00 11.09 ? 242 GLN A CB 1 ATOM 1820 C CG . GLN A 1 242 ? 22.111 40.627 1.127 1.00 12.47 ? 242 GLN A CG 1 ATOM 1821 C CD . GLN A 1 242 ? 21.268 40.751 -0.127 1.00 12.11 ? 242 GLN A CD 1 ATOM 1822 O OE1 . GLN A 1 242 ? 20.749 41.814 -0.411 1.00 13.32 ? 242 GLN A OE1 1 ATOM 1823 N NE2 . GLN A 1 242 ? 21.164 39.648 -0.875 1.00 13.87 ? 242 GLN A NE2 1 ATOM 1824 N N . LEU A 1 243 ? 24.376 43.566 4.472 1.00 9.29 ? 243 LEU A N 1 ATOM 1825 C CA . LEU A 1 243 ? 25.192 44.742 4.820 1.00 8.31 ? 243 LEU A CA 1 ATOM 1826 C C . LEU A 1 243 ? 26.661 44.342 4.869 1.00 9.47 ? 243 LEU A C 1 ATOM 1827 O O . LEU A 1 243 ? 27.522 45.262 4.890 1.00 10.64 ? 243 LEU A O 1 ATOM 1828 C CB . LEU A 1 243 ? 24.736 45.314 6.154 1.00 9.76 ? 243 LEU A CB 1 ATOM 1829 C CG . LEU A 1 243 ? 23.354 45.959 6.107 1.00 10.10 ? 243 LEU A CG 1 ATOM 1830 C CD1 . LEU A 1 243 ? 22.860 46.105 7.560 1.00 13.27 ? 243 LEU A CD1 1 ATOM 1831 C CD2 . LEU A 1 243 ? 23.402 47.347 5.464 1.00 10.96 ? 243 LEU A CD2 1 ATOM 1832 N N . GLU A 1 244 ? 27.001 43.057 4.954 1.00 8.88 ? 244 GLU A N 1 ATOM 1833 C CA . GLU A 1 244 ? 28.390 42.587 4.829 1.00 8.38 ? 244 GLU A CA 1 ATOM 1834 C C . GLU A 1 244 ? 28.402 41.808 3.531 1.00 9.29 ? 244 GLU A C 1 ATOM 1835 O O . GLU A 1 244 ? 27.578 40.877 3.309 1.00 10.14 ? 244 GLU A O 1 ATOM 1836 C CB . GLU A 1 244 ? 28.847 41.751 6.027 1.00 8.23 ? 244 GLU A CB 1 ATOM 1837 C CG . GLU A 1 244 ? 29.171 42.666 7.200 1.00 9.63 ? 244 GLU A CG 1 ATOM 1838 C CD . GLU A 1 244 ? 29.475 41.973 8.531 1.00 10.86 ? 244 GLU A CD 1 ATOM 1839 O OE1 . GLU A 1 244 ? 28.877 40.921 8.823 1.00 11.50 ? 244 GLU A OE1 1 ATOM 1840 O OE2 . GLU A 1 244 ? 30.309 42.536 9.297 1.00 10.72 ? 244 GLU A OE2 1 ATOM 1841 N N . PHE A 1 245 ? 29.379 42.093 2.674 1.00 8.68 ? 245 PHE A N 1 ATOM 1842 C CA . PHE A 1 245 ? 29.412 41.486 1.335 1.00 8.39 ? 245 PHE A CA 1 ATOM 1843 C C . PHE A 1 245 ? 30.819 41.450 0.783 1.00 7.67 ? 245 PHE A C 1 ATOM 1844 O O . PHE A 1 245 ? 31.676 42.239 1.249 1.00 8.96 ? 245 PHE A O 1 ATOM 1845 C CB . PHE A 1 245 ? 28.456 42.263 0.372 1.00 8.65 ? 245 PHE A CB 1 ATOM 1846 C CG . PHE A 1 245 ? 28.622 43.776 0.424 1.00 8.00 ? 245 PHE A CG 1 ATOM 1847 C CD1 . PHE A 1 245 ? 29.565 44.425 -0.384 1.00 8.29 ? 245 PHE A CD1 1 ATOM 1848 C CD2 . PHE A 1 245 ? 27.818 44.524 1.274 1.00 9.42 ? 245 PHE A CD2 1 ATOM 1849 C CE1 . PHE A 1 245 ? 29.706 45.826 -0.342 1.00 8.42 ? 245 PHE A CE1 1 ATOM 1850 C CE2 . PHE A 1 245 ? 27.954 45.950 1.322 1.00 9.57 ? 245 PHE A CE2 1 ATOM 1851 C CZ . PHE A 1 245 ? 28.906 46.576 0.500 1.00 9.49 ? 245 PHE A CZ 1 ATOM 1852 N N . LEU A 1 246 ? 31.046 40.618 -0.208 1.00 8.92 ? 246 LEU A N 1 ATOM 1853 C CA . LEU A 1 246 ? 32.316 40.550 -0.906 1.00 8.34 ? 246 LEU A CA 1 ATOM 1854 C C . LEU A 1 246 ? 32.170 41.469 -2.128 1.00 8.04 ? 246 LEU A C 1 ATOM 1855 O O . LEU A 1 246 ? 31.501 41.151 -3.107 1.00 9.08 ? 246 LEU A O 1 ATOM 1856 C CB . LEU A 1 246 ? 32.613 39.088 -1.324 1.00 10.38 ? 246 LEU A CB 1 ATOM 1857 C CG . LEU A 1 246 ? 32.936 38.196 -0.085 1.00 13.35 ? 246 LEU A CG 1 ATOM 1858 C CD1 . LEU A 1 246 ? 32.832 36.720 -0.533 1.00 17.02 ? 246 LEU A CD1 1 ATOM 1859 C CD2 . LEU A 1 246 ? 34.347 38.542 0.403 1.00 19.34 ? 246 LEU A CD2 1 ATOM 1860 N N . TRP A 1 247 ? 32.785 42.646 -2.025 1.00 8.22 ? 247 TRP A N 1 ATOM 1861 C CA . TRP A 1 247 ? 32.611 43.684 -3.053 1.00 7.66 ? 247 TRP A CA 1 ATOM 1862 C C . TRP A 1 247 ? 33.647 43.480 -4.136 1.00 7.36 ? 247 TRP A C 1 ATOM 1863 O O . TRP A 1 247 ? 34.851 43.651 -3.924 1.00 8.31 ? 247 TRP A O 1 ATOM 1864 C CB . TRP A 1 247 ? 32.784 45.027 -2.375 1.00 7.99 ? 247 TRP A CB 1 ATOM 1865 C CG . TRP A 1 247 ? 32.336 46.216 -3.225 1.00 7.24 ? 247 TRP A CG 1 ATOM 1866 C CD1 . TRP A 1 247 ? 31.814 46.206 -4.493 1.00 7.92 ? 247 TRP A CD1 1 ATOM 1867 C CD2 . TRP A 1 247 ? 32.356 47.583 -2.788 1.00 7.14 ? 247 TRP A CD2 1 ATOM 1868 N NE1 . TRP A 1 247 ? 31.471 47.504 -4.870 1.00 8.05 ? 247 TRP A NE1 1 ATOM 1869 C CE2 . TRP A 1 247 ? 31.800 48.351 -3.839 1.00 6.68 ? 247 TRP A CE2 1 ATOM 1870 C CE3 . TRP A 1 247 ? 32.774 48.236 -1.602 1.00 7.77 ? 247 TRP A CE3 1 ATOM 1871 C CZ2 . TRP A 1 247 ? 31.679 49.772 -3.749 1.00 8.27 ? 247 TRP A CZ2 1 ATOM 1872 C CZ3 . TRP A 1 247 ? 32.637 49.609 -1.527 1.00 7.66 ? 247 TRP A CZ3 1 ATOM 1873 C CH2 . TRP A 1 247 ? 32.111 50.373 -2.585 1.00 6.96 ? 247 TRP A CH2 1 ATOM 1874 N N . ARG A 1 248 ? 33.156 43.071 -5.323 1.00 7.61 ? 248 ARG A N 1 ATOM 1875 C CA . ARG A 1 248 ? 34.045 42.880 -6.460 1.00 7.78 ? 248 ARG A CA 1 ATOM 1876 C C . ARG A 1 248 ? 33.779 43.968 -7.523 1.00 7.82 ? 248 ARG A C 1 ATOM 1877 O O . ARG A 1 248 ? 32.739 44.632 -7.490 1.00 8.04 ? 248 ARG A O 1 ATOM 1878 C CB . ARG A 1 248 ? 33.841 41.495 -7.131 1.00 8.60 ? 248 ARG A CB 1 ATOM 1879 C CG . ARG A 1 248 ? 32.440 41.339 -7.784 1.00 8.19 ? 248 ARG A CG 1 ATOM 1880 C CD . ARG A 1 248 ? 32.381 40.037 -8.639 1.00 11.95 ? 248 ARG A CD 1 ATOM 1881 N NE . ARG A 1 248 ? 32.426 38.885 -7.724 1.00 11.26 ? 248 ARG A NE 1 ATOM 1882 C CZ . ARG A 1 248 ? 32.407 37.624 -8.185 1.00 13.15 ? 248 ARG A CZ 1 ATOM 1883 N NH1 . ARG A 1 248 ? 32.370 37.387 -9.492 1.00 14.79 ? 248 ARG A NH1 1 ATOM 1884 N NH2 . ARG A 1 248 ? 32.367 36.609 -7.312 1.00 15.01 ? 248 ARG A NH2 1 ATOM 1885 N N . GLN A 1 249 ? 34.722 44.119 -8.459 1.00 7.67 ? 249 GLN A N 1 ATOM 1886 C CA . GLN A 1 249 ? 34.532 45.096 -9.548 1.00 7.53 ? 249 GLN A CA 1 ATOM 1887 C C . GLN A 1 249 ? 33.420 44.648 -10.496 1.00 8.48 ? 249 GLN A C 1 ATOM 1888 O O . GLN A 1 249 ? 33.150 43.453 -10.671 1.00 10.17 ? 249 GLN A O 1 ATOM 1889 C CB . GLN A 1 249 ? 35.834 45.308 -10.339 1.00 9.28 ? 249 GLN A CB 1 ATOM 1890 C CG . GLN A 1 249 ? 36.958 45.790 -9.396 1.00 8.69 ? 249 GLN A CG 1 ATOM 1891 C CD . GLN A 1 249 ? 36.570 47.071 -8.647 1.00 8.71 ? 249 GLN A CD 1 ATOM 1892 O OE1 . GLN A 1 249 ? 36.554 47.124 -7.352 1.00 10.77 ? 249 GLN A OE1 1 ATOM 1893 N NE2 . GLN A 1 249 ? 36.239 48.096 -9.373 1.00 7.23 ? 249 GLN A NE2 1 ATOM 1894 N N . ILE A 1 250 ? 32.783 45.614 -11.151 1.00 8.35 ? 250 ILE A N 1 ATOM 1895 C CA . ILE A 1 250 ? 31.623 45.316 -11.991 1.00 9.34 ? 250 ILE A CA 1 ATOM 1896 C C . ILE A 1 250 ? 31.929 44.408 -13.171 1.00 9.30 ? 250 ILE A C 1 ATOM 1897 O O . ILE A 1 250 ? 30.988 43.736 -13.668 1.00 11.25 ? 250 ILE A O 1 ATOM 1898 C CB . ILE A 1 250 ? 30.896 46.627 -12.522 1.00 11.01 ? 250 ILE A CB 1 ATOM 1899 C CG1 . ILE A 1 250 ? 31.890 47.535 -13.284 1.00 11.67 ? 250 ILE A CG1 1 ATOM 1900 C CG2 . ILE A 1 250 ? 30.254 47.378 -11.371 1.00 11.33 ? 250 ILE A CG2 1 ATOM 1901 C CD1 . ILE A 1 250 ? 31.243 48.869 -13.815 1.00 12.24 ? 250 ILE A CD1 1 ATOM 1902 N N . TRP A 1 251 ? 33.175 44.356 -13.604 1.00 10.36 ? 251 TRP A N 1 ATOM 1903 C CA . TRP A 1 251 ? 33.551 43.500 -14.741 1.00 10.54 ? 251 TRP A CA 1 ATOM 1904 C C . TRP A 1 251 ? 34.194 42.190 -14.342 1.00 15.47 ? 251 TRP A C 1 ATOM 1905 O O . TRP A 1 251 ? 34.491 41.349 -15.213 1.00 16.27 ? 251 TRP A O 1 ATOM 1906 C CB . TRP A 1 251 ? 34.546 44.218 -15.669 1.00 12.86 ? 251 TRP A CB 1 ATOM 1907 C CG . TRP A 1 251 ? 35.779 44.349 -14.981 1.00 16.34 ? 251 TRP A CG 1 ATOM 1908 C CD1 . TRP A 1 251 ? 36.745 43.375 -14.816 1.00 17.91 ? 251 TRP A CD1 1 ATOM 1909 C CD2 . TRP A 1 251 ? 36.209 45.473 -14.260 1.00 14.46 ? 251 TRP A CD2 1 ATOM 1910 N NE1 . TRP A 1 251 ? 37.721 43.848 -14.048 1.00 16.28 ? 251 TRP A NE1 1 ATOM 1911 C CE2 . TRP A 1 251 ? 37.442 45.139 -13.669 1.00 14.70 ? 251 TRP A CE2 1 ATOM 1912 C CE3 . TRP A 1 251 ? 35.677 46.728 -14.033 1.00 13.93 ? 251 TRP A CE3 1 ATOM 1913 C CZ2 . TRP A 1 251 ? 38.168 46.012 -12.865 1.00 17.43 ? 251 TRP A CZ2 1 ATOM 1914 C CZ3 . TRP A 1 251 ? 36.392 47.609 -13.234 1.00 16.01 ? 251 TRP A CZ3 1 ATOM 1915 C CH2 . TRP A 1 251 ? 37.623 47.247 -12.663 1.00 18.78 ? 251 TRP A CH2 1 ATOM 1916 N N . ASP A 1 252 ? 34.381 41.957 -13.043 1.00 13.10 ? 252 ASP A N 1 ATOM 1917 C CA . ASP A 1 252 ? 35.108 40.780 -12.570 1.00 14.29 ? 252 ASP A CA 1 ATOM 1918 C C . ASP A 1 252 ? 34.289 39.510 -12.482 1.00 13.75 ? 252 ASP A C 1 ATOM 1919 O O . ASP A 1 252 ? 33.543 39.292 -11.563 1.00 14.48 ? 252 ASP A O 1 ATOM 1920 C CB . ASP A 1 252 ? 35.720 41.177 -11.216 1.00 11.67 ? 252 ASP A CB 1 ATOM 1921 C CG . ASP A 1 252 ? 36.471 40.038 -10.552 1.00 16.60 ? 252 ASP A CG 1 ATOM 1922 O OD1 . ASP A 1 252 ? 36.725 39.002 -11.229 1.00 18.75 ? 252 ASP A OD1 1 ATOM 1923 O OD2 . ASP A 1 252 ? 36.795 40.195 -9.370 1.00 15.70 ? 252 ASP A OD2 1 ATOM 1924 N N A ASN A 1 253 ? 34.402 38.664 -13.504 0.50 13.24 ? 253 ASN A N 1 ATOM 1925 N N B ASN A 1 253 ? 34.402 38.664 -13.504 0.50 15.59 ? 253 ASN A N 1 ATOM 1926 C CA A ASN A 1 253 ? 33.639 37.422 -13.524 0.50 11.83 ? 253 ASN A CA 1 ATOM 1927 C CA B ASN A 1 253 ? 33.639 37.422 -13.524 0.50 16.45 ? 253 ASN A CA 1 ATOM 1928 C C A ASN A 1 253 ? 34.077 36.361 -12.503 0.50 13.45 ? 253 ASN A C 1 ATOM 1929 C C B ASN A 1 253 ? 34.077 36.361 -12.503 0.50 16.15 ? 253 ASN A C 1 ATOM 1930 O O A ASN A 1 253 ? 33.248 35.717 -11.904 0.50 17.48 ? 253 ASN A O 1 ATOM 1931 O O B ASN A 1 253 ? 33.248 35.717 -11.904 0.50 19.07 ? 253 ASN A O 1 ATOM 1932 C CB A ASN A 1 253 ? 33.741 36.816 -14.953 0.50 14.24 ? 253 ASN A CB 1 ATOM 1933 C CB B ASN A 1 253 ? 33.741 36.816 -14.953 0.50 22.62 ? 253 ASN A CB 1 ATOM 1934 C CG A ASN A 1 253 ? 32.932 35.570 -15.090 0.50 18.23 ? 253 ASN A CG 1 ATOM 1935 C CG B ASN A 1 253 ? 32.461 36.182 -15.383 0.50 29.63 ? 253 ASN A CG 1 ATOM 1936 O OD1 A ASN A 1 253 ? 33.468 34.498 -15.416 0.50 19.15 ? 253 ASN A OD1 1 ATOM 1937 O OD1 B ASN A 1 253 ? 32.330 34.947 -15.376 0.50 36.16 ? 253 ASN A OD1 1 ATOM 1938 N ND2 A ASN A 1 253 ? 31.641 35.676 -14.845 0.50 13.37 ? 253 ASN A ND2 1 ATOM 1939 N ND2 B ASN A 1 253 ? 31.497 36.999 -15.760 0.50 29.42 ? 253 ASN A ND2 1 ATOM 1940 N N . LYS A 1 254 ? 35.364 36.305 -12.274 1.00 16.64 ? 254 LYS A N 1 ATOM 1941 C CA . LYS A 1 254 ? 35.892 35.269 -11.366 1.00 20.85 ? 254 LYS A CA 1 ATOM 1942 C C . LYS A 1 254 ? 35.837 35.652 -9.900 1.00 20.19 ? 254 LYS A C 1 ATOM 1943 O O . LYS A 1 254 ? 35.693 34.789 -9.030 1.00 22.37 ? 254 LYS A O 1 ATOM 1944 C CB . LYS A 1 254 ? 37.329 34.961 -11.756 1.00 27.31 ? 254 LYS A CB 1 ATOM 1945 C CG . LYS A 1 254 ? 37.985 33.759 -11.060 1.00 33.99 ? 254 LYS A CG 1 ATOM 1946 C CD . LYS A 1 254 ? 39.385 33.542 -11.678 1.00 36.50 ? 254 LYS A CD 1 ATOM 1947 C CE . LYS A 1 254 ? 40.155 32.356 -11.073 1.00 38.12 ? 254 LYS A CE 1 ATOM 1948 N NZ . LYS A 1 254 ? 40.469 32.479 -9.620 1.00 39.80 ? 254 LYS A NZ 1 ATOM 1949 N N . GLY A 1 255 ? 35.957 36.943 -9.600 1.00 16.29 ? 255 GLY A N 1 ATOM 1950 C CA . GLY A 1 255 ? 35.910 37.343 -8.194 1.00 16.93 ? 255 GLY A CA 1 ATOM 1951 C C . GLY A 1 255 ? 37.267 37.624 -7.559 1.00 14.93 ? 255 GLY A C 1 ATOM 1952 O O . GLY A 1 255 ? 37.275 37.921 -6.368 1.00 15.10 ? 255 GLY A O 1 ATOM 1953 N N . ASP A 1 256 ? 38.377 37.637 -8.293 1.00 15.87 ? 256 ASP A N 1 ATOM 1954 C CA . ASP A 1 256 ? 39.677 37.887 -7.669 1.00 19.35 ? 256 ASP A CA 1 ATOM 1955 C C . ASP A 1 256 ? 39.878 39.292 -7.119 1.00 16.18 ? 256 ASP A C 1 ATOM 1956 O O . ASP A 1 256 ? 40.769 39.531 -6.328 1.00 16.90 ? 256 ASP A O 1 ATOM 1957 C CB . ASP A 1 256 ? 40.839 37.577 -8.630 1.00 26.30 ? 256 ASP A CB 1 ATOM 1958 C CG . ASP A 1 256 ? 40.897 36.095 -9.028 1.00 36.40 ? 256 ASP A CG 1 ATOM 1959 O OD1 . ASP A 1 256 ? 40.395 35.249 -8.253 1.00 36.86 ? 256 ASP A OD1 1 ATOM 1960 O OD2 . ASP A 1 256 ? 41.458 35.799 -10.115 1.00 39.66 ? 256 ASP A OD2 1 ATOM 1961 N N . THR A 1 257 ? 39.029 40.239 -7.517 1.00 12.18 ? 257 THR A N 1 ATOM 1962 C CA . THR A 1 257 ? 39.155 41.594 -6.958 1.00 12.08 ? 257 THR A CA 1 ATOM 1963 C C . THR A 1 257 ? 38.365 41.774 -5.651 1.00 12.25 ? 257 THR A C 1 ATOM 1964 O O . THR A 1 257 ? 38.427 42.853 -5.044 1.00 12.10 ? 257 THR A O 1 ATOM 1965 C CB . THR A 1 257 ? 38.581 42.678 -7.958 1.00 12.47 ? 257 THR A CB 1 ATOM 1966 O OG1 . THR A 1 257 ? 37.176 42.459 -8.146 1.00 11.35 ? 257 THR A OG1 1 ATOM 1967 C CG2 . THR A 1 257 ? 39.360 42.648 -9.289 1.00 13.56 ? 257 THR A CG2 1 ATOM 1968 N N . ALA A 1 258 ? 37.604 40.748 -5.251 1.00 10.57 ? 258 ALA A N 1 ATOM 1969 C CA . ALA A 1 258 ? 36.713 40.886 -4.096 1.00 11.03 ? 258 ALA A CA 1 ATOM 1970 C C . ALA A 1 258 ? 37.381 41.293 -2.793 1.00 9.91 ? 258 ALA A C 1 ATOM 1971 O O . ALA A 1 258 ? 38.450 40.790 -2.456 1.00 11.64 ? 258 ALA A O 1 ATOM 1972 C CB . ALA A 1 258 ? 35.916 39.598 -3.817 1.00 10.84 ? 258 ALA A CB 1 ATOM 1973 N N . LEU A 1 259 ? 36.725 42.195 -2.078 1.00 8.61 ? 259 LEU A N 1 ATOM 1974 C CA . LEU A 1 259 ? 37.183 42.629 -0.748 1.00 8.40 ? 259 LEU A CA 1 ATOM 1975 C C . LEU A 1 259 ? 35.989 42.620 0.178 1.00 8.53 ? 259 LEU A C 1 ATOM 1976 O O . LEU A 1 259 ? 34.945 43.238 -0.090 1.00 8.38 ? 259 LEU A O 1 ATOM 1977 C CB . LEU A 1 259 ? 37.781 44.019 -0.831 1.00 9.41 ? 259 LEU A CB 1 ATOM 1978 C CG . LEU A 1 259 ? 38.525 44.417 0.465 1.00 8.08 ? 259 LEU A CG 1 ATOM 1979 C CD1 . LEU A 1 259 ? 39.800 43.530 0.744 1.00 10.23 ? 259 LEU A CD1 1 ATOM 1980 C CD2 . LEU A 1 259 ? 38.990 45.884 0.296 1.00 10.95 ? 259 LEU A CD2 1 ATOM 1981 N N . PHE A 1 260 ? 36.152 41.961 1.343 1.00 8.35 ? 260 PHE A N 1 ATOM 1982 C CA . PHE A 1 260 ? 35.070 41.932 2.319 1.00 7.71 ? 260 PHE A CA 1 ATOM 1983 C C . PHE A 1 260 ? 34.764 43.326 2.804 1.00 7.20 ? 260 PHE A C 1 ATOM 1984 O O . PHE A 1 260 ? 35.681 44.065 3.259 1.00 8.23 ? 260 PHE A O 1 ATOM 1985 C CB . PHE A 1 260 ? 35.500 41.011 3.509 1.00 8.36 ? 260 PHE A CB 1 ATOM 1986 C CG . PHE A 1 260 ? 34.393 40.863 4.547 1.00 8.30 ? 260 PHE A CG 1 ATOM 1987 C CD1 . PHE A 1 260 ? 33.407 39.900 4.328 1.00 10.41 ? 260 PHE A CD1 1 ATOM 1988 C CD2 . PHE A 1 260 ? 34.295 41.624 5.673 1.00 8.77 ? 260 PHE A CD2 1 ATOM 1989 C CE1 . PHE A 1 260 ? 32.330 39.719 5.271 1.00 12.68 ? 260 PHE A CE1 1 ATOM 1990 C CE2 . PHE A 1 260 ? 33.230 41.478 6.634 1.00 10.50 ? 260 PHE A CE2 1 ATOM 1991 C CZ . PHE A 1 260 ? 32.253 40.522 6.422 1.00 12.73 ? 260 PHE A CZ 1 ATOM 1992 N N . THR A 1 261 ? 33.475 43.686 2.782 1.00 7.39 ? 261 THR A N 1 ATOM 1993 C CA . THR A 1 261 ? 33.064 45.033 3.133 1.00 7.61 ? 261 THR A CA 1 ATOM 1994 C C . THR A 1 261 ? 31.922 44.982 4.158 1.00 7.81 ? 261 THR A C 1 ATOM 1995 O O . THR A 1 261 ? 30.955 44.215 3.983 1.00 9.11 ? 261 THR A O 1 ATOM 1996 C CB . THR A 1 261 ? 32.552 45.769 1.835 1.00 8.18 ? 261 THR A CB 1 ATOM 1997 O OG1 . THR A 1 261 ? 33.613 45.824 0.895 1.00 8.43 ? 261 THR A OG1 1 ATOM 1998 C CG2 . THR A 1 261 ? 32.111 47.163 2.114 1.00 9.04 ? 261 THR A CG2 1 ATOM 1999 N N . HIS A 1 262 ? 32.021 45.865 5.157 1.00 7.44 ? 262 HIS A N 1 ATOM 2000 C CA . HIS A 1 262 ? 30.961 46.050 6.137 1.00 7.00 ? 262 HIS A CA 1 ATOM 2001 C C . HIS A 1 262 ? 30.336 47.429 5.955 1.00 7.92 ? 262 HIS A C 1 ATOM 2002 O O . HIS A 1 262 ? 31.043 48.460 6.081 1.00 8.28 ? 262 HIS A O 1 ATOM 2003 C CB . HIS A 1 262 ? 31.593 45.961 7.561 1.00 8.69 ? 262 HIS A CB 1 ATOM 2004 C CG . HIS A 1 262 ? 30.640 46.302 8.659 1.00 7.80 ? 262 HIS A CG 1 ATOM 2005 N ND1 . HIS A 1 262 ? 30.042 45.325 9.429 1.00 9.11 ? 262 HIS A ND1 1 ATOM 2006 C CD2 . HIS A 1 262 ? 30.171 47.491 9.106 1.00 7.99 ? 262 HIS A CD2 1 ATOM 2007 C CE1 . HIS A 1 262 ? 29.255 45.923 10.324 1.00 10.35 ? 262 HIS A CE1 1 ATOM 2008 N NE2 . HIS A 1 262 ? 29.297 47.239 10.145 1.00 9.70 ? 262 HIS A NE2 1 ATOM 2009 N N . MET A 1 263 ? 29.055 47.489 5.626 1.00 7.93 ? 263 MET A N 1 ATOM 2010 C CA . MET A 1 263 ? 28.327 48.732 5.564 1.00 7.30 ? 263 MET A CA 1 ATOM 2011 C C . MET A 1 263 ? 27.604 48.921 6.920 1.00 8.43 ? 263 MET A C 1 ATOM 2012 O O . MET A 1 263 ? 26.832 48.010 7.345 1.00 9.53 ? 263 MET A O 1 ATOM 2013 C CB . MET A 1 263 ? 27.297 48.666 4.423 1.00 8.36 ? 263 MET A CB 1 ATOM 2014 C CG . MET A 1 263 ? 26.506 49.975 4.301 1.00 8.88 ? 263 MET A CG 1 ATOM 2015 S SD . MET A 1 263 ? 25.161 49.871 3.090 1.00 9.89 ? 263 MET A SD 1 ATOM 2016 C CE . MET A 1 263 ? 26.017 49.481 1.545 1.00 10.44 ? 263 MET A CE 1 ATOM 2017 N N A MET A 1 264 ? 27.815 50.057 7.588 0.50 5.95 ? 264 MET A N 1 ATOM 2018 N N B MET A 1 264 ? 27.844 50.054 7.602 0.50 11.07 ? 264 MET A N 1 ATOM 2019 C CA A MET A 1 264 ? 27.097 50.396 8.839 0.50 5.60 ? 264 MET A CA 1 ATOM 2020 C CA B MET A 1 264 ? 27.082 50.392 8.797 0.50 13.63 ? 264 MET A CA 1 ATOM 2021 C C A MET A 1 264 ? 25.625 50.609 8.439 0.50 6.25 ? 264 MET A C 1 ATOM 2022 C C B MET A 1 264 ? 25.611 50.616 8.467 0.50 11.71 ? 264 MET A C 1 ATOM 2023 O O A MET A 1 264 ? 25.303 51.066 7.323 0.50 8.63 ? 264 MET A O 1 ATOM 2024 O O B MET A 1 264 ? 25.303 51.066 7.323 0.50 11.77 ? 264 MET A O 1 ATOM 2025 C CB A MET A 1 264 ? 27.723 51.591 9.504 0.50 4.21 ? 264 MET A CB 1 ATOM 2026 C CB B MET A 1 264 ? 27.673 51.629 9.476 0.50 21.14 ? 264 MET A CB 1 ATOM 2027 C CG A MET A 1 264 ? 29.189 51.301 9.933 0.50 2.37 ? 264 MET A CG 1 ATOM 2028 C CG B MET A 1 264 ? 29.071 51.421 10.036 0.50 31.92 ? 264 MET A CG 1 ATOM 2029 S SD A MET A 1 264 ? 30.089 52.852 10.468 0.50 7.68 ? 264 MET A SD 1 ATOM 2030 S SD B MET A 1 264 ? 29.334 52.292 11.592 0.50 40.26 ? 264 MET A SD 1 ATOM 2031 C CE A MET A 1 264 ? 29.046 53.566 11.595 0.50 6.89 ? 264 MET A CE 1 ATOM 2032 C CE B MET A 1 264 ? 29.486 53.981 11.014 0.50 41.29 ? 264 MET A CE 1 ATOM 2033 N N . PRO A 1 265 ? 24.710 50.343 9.384 1.00 9.36 ? 265 PRO A N 1 ATOM 2034 C CA . PRO A 1 265 ? 23.286 50.382 9.014 1.00 10.04 ? 265 PRO A CA 1 ATOM 2035 C C . PRO A 1 265 ? 22.463 51.594 9.189 1.00 10.47 ? 265 PRO A C 1 ATOM 2036 O O . PRO A 1 265 ? 21.391 51.646 8.592 1.00 10.83 ? 265 PRO A O 1 ATOM 2037 C CB . PRO A 1 265 ? 22.687 49.224 9.898 1.00 11.35 ? 265 PRO A CB 1 ATOM 2038 C CG . PRO A 1 265 ? 23.515 49.325 11.161 1.00 13.47 ? 265 PRO A CG 1 ATOM 2039 C CD . PRO A 1 265 ? 24.948 49.771 10.732 1.00 9.64 ? 265 PRO A CD 1 ATOM 2040 N N . PHE A 1 266 ? 22.939 52.540 9.961 1.00 9.86 ? 266 PHE A N 1 ATOM 2041 C CA . PHE A 1 266 ? 22.157 53.654 10.412 1.00 10.21 ? 266 PHE A CA 1 ATOM 2042 C C . PHE A 1 266 ? 22.543 55.002 9.821 1.00 10.12 ? 266 PHE A C 1 ATOM 2043 O O . PHE A 1 266 ? 23.443 55.112 8.996 1.00 10.68 ? 266 PHE A O 1 ATOM 2044 C CB . PHE A 1 266 ? 22.127 53.638 11.967 1.00 10.25 ? 266 PHE A CB 1 ATOM 2045 C CG . PHE A 1 266 ? 21.565 52.305 12.567 1.00 11.23 ? 266 PHE A CG 1 ATOM 2046 C CD1 . PHE A 1 266 ? 22.201 51.737 13.664 1.00 10.98 ? 266 PHE A CD1 1 ATOM 2047 C CD2 . PHE A 1 266 ? 20.424 51.664 12.022 1.00 11.53 ? 266 PHE A CD2 1 ATOM 2048 C CE1 . PHE A 1 266 ? 21.695 50.536 14.235 1.00 11.52 ? 266 PHE A CE1 1 ATOM 2049 C CE2 . PHE A 1 266 ? 19.939 50.469 12.596 1.00 10.98 ? 266 PHE A CE2 1 ATOM 2050 C CZ . PHE A 1 266 ? 20.563 49.926 13.675 1.00 10.69 ? 266 PHE A CZ 1 ATOM 2051 N N . TYR A 1 267 ? 21.861 56.032 10.263 1.00 9.86 ? 267 TYR A N 1 ATOM 2052 C CA . TYR A 1 267 ? 21.949 57.344 9.640 1.00 9.49 ? 267 TYR A CA 1 ATOM 2053 C C . TYR A 1 267 ? 23.286 58.054 9.881 1.00 10.68 ? 267 TYR A C 1 ATOM 2054 O O . TYR A 1 267 ? 23.686 58.868 9.039 1.00 10.86 ? 267 TYR A O 1 ATOM 2055 C CB . TYR A 1 267 ? 20.787 58.183 10.198 1.00 12.29 ? 267 TYR A CB 1 ATOM 2056 C CG . TYR A 1 267 ? 20.898 59.700 10.091 1.00 11.25 ? 267 TYR A CG 1 ATOM 2057 C CD1 . TYR A 1 267 ? 20.583 60.366 8.910 1.00 13.98 ? 267 TYR A CD1 1 ATOM 2058 C CD2 . TYR A 1 267 ? 21.302 60.464 11.196 1.00 12.54 ? 267 TYR A CD2 1 ATOM 2059 C CE1 . TYR A 1 267 ? 20.666 61.761 8.809 1.00 13.32 ? 267 TYR A CE1 1 ATOM 2060 C CE2 . TYR A 1 267 ? 21.378 61.840 11.107 1.00 14.35 ? 267 TYR A CE2 1 ATOM 2061 C CZ . TYR A 1 267 ? 21.051 62.466 9.914 1.00 14.91 ? 267 TYR A CZ 1 ATOM 2062 O OH . TYR A 1 267 ? 21.060 63.870 9.869 1.00 19.28 ? 267 TYR A OH 1 ATOM 2063 N N . SER A 1 268 ? 23.984 57.754 10.963 1.00 9.93 ? 268 SER A N 1 ATOM 2064 C CA . SER A 1 268 ? 25.247 58.435 11.291 1.00 10.87 ? 268 SER A CA 1 ATOM 2065 C C . SER A 1 268 ? 26.190 57.487 11.972 1.00 9.63 ? 268 SER A C 1 ATOM 2066 O O . SER A 1 268 ? 25.783 56.373 12.399 1.00 10.39 ? 268 SER A O 1 ATOM 2067 C CB . SER A 1 268 ? 24.933 59.613 12.244 1.00 10.37 ? 268 SER A CB 1 ATOM 2068 O OG . SER A 1 268 ? 26.123 60.255 12.715 1.00 12.18 ? 268 SER A OG 1 ATOM 2069 N N . TYR A 1 269 ? 27.495 57.873 12.054 1.00 10.29 ? 269 TYR A N 1 ATOM 2070 C CA . TYR A 1 269 ? 28.467 57.130 12.857 1.00 9.44 ? 269 TYR A CA 1 ATOM 2071 C C . TYR A 1 269 ? 28.552 57.648 14.299 1.00 10.22 ? 269 TYR A C 1 ATOM 2072 O O . TYR A 1 269 ? 29.400 57.180 15.059 1.00 10.19 ? 269 TYR A O 1 ATOM 2073 C CB . TYR A 1 269 ? 29.883 57.231 12.195 1.00 9.42 ? 269 TYR A CB 1 ATOM 2074 C CG . TYR A 1 269 ? 30.343 58.651 11.930 1.00 10.93 ? 269 TYR A CG 1 ATOM 2075 C CD1 . TYR A 1 269 ? 30.789 59.477 12.947 1.00 9.92 ? 269 TYR A CD1 1 ATOM 2076 C CD2 . TYR A 1 269 ? 30.266 59.158 10.635 1.00 11.20 ? 269 TYR A CD2 1 ATOM 2077 C CE1 . TYR A 1 269 ? 31.177 60.792 12.718 1.00 10.97 ? 269 TYR A CE1 1 ATOM 2078 C CE2 . TYR A 1 269 ? 30.662 60.504 10.362 1.00 11.47 ? 269 TYR A CE2 1 ATOM 2079 C CZ . TYR A 1 269 ? 31.106 61.280 11.436 1.00 10.75 ? 269 TYR A CZ 1 ATOM 2080 O OH . TYR A 1 269 ? 31.439 62.603 11.115 1.00 12.93 ? 269 TYR A OH 1 ATOM 2081 N N . ASP A 1 270 ? 27.748 58.648 14.652 1.00 9.72 ? 270 ASP A N 1 ATOM 2082 C CA . ASP A 1 270 ? 27.766 59.140 16.045 1.00 9.93 ? 270 ASP A CA 1 ATOM 2083 C C . ASP A 1 270 ? 27.190 58.106 17.040 1.00 9.87 ? 270 ASP A C 1 ATOM 2084 O O . ASP A 1 270 ? 26.637 57.086 16.605 1.00 10.04 ? 270 ASP A O 1 ATOM 2085 C CB . ASP A 1 270 ? 27.103 60.534 16.125 1.00 11.66 ? 270 ASP A CB 1 ATOM 2086 C CG . ASP A 1 270 ? 25.596 60.529 15.909 1.00 14.66 ? 270 ASP A CG 1 ATOM 2087 O OD1 . ASP A 1 270 ? 24.952 59.445 15.801 1.00 14.08 ? 270 ASP A OD1 1 ATOM 2088 O OD2 . ASP A 1 270 ? 25.025 61.685 15.889 1.00 16.35 ? 270 ASP A OD2 1 ATOM 2089 N N . ILE A 1 271 ? 27.401 58.325 18.325 1.00 9.75 ? 271 ILE A N 1 ATOM 2090 C CA . ILE A 1 271 ? 26.986 57.317 19.307 1.00 10.28 ? 271 ILE A CA 1 ATOM 2091 C C . ILE A 1 271 ? 25.456 57.046 19.268 1.00 9.26 ? 271 ILE A C 1 ATOM 2092 O O . ILE A 1 271 ? 25.055 55.888 19.294 1.00 10.33 ? 271 ILE A O 1 ATOM 2093 C CB . ILE A 1 271 ? 27.522 57.657 20.688 1.00 11.07 ? 271 ILE A CB 1 ATOM 2094 C CG1 . ILE A 1 271 ? 29.061 57.533 20.621 1.00 10.22 ? 271 ILE A CG1 1 ATOM 2095 C CG2 . ILE A 1 271 ? 26.952 56.690 21.725 1.00 11.12 ? 271 ILE A CG2 1 ATOM 2096 C CD1 . ILE A 1 271 ? 29.775 58.201 21.769 1.00 10.10 ? 271 ILE A CD1 1 ATOM 2097 N N . PRO A 1 272 ? 24.629 58.089 19.120 1.00 10.46 ? 272 PRO A N 1 ATOM 2098 C CA . PRO A 1 272 ? 23.176 57.827 19.062 1.00 11.04 ? 272 PRO A CA 1 ATOM 2099 C C . PRO A 1 272 ? 22.798 56.916 17.918 1.00 12.60 ? 272 PRO A C 1 ATOM 2100 O O . PRO A 1 272 ? 21.720 56.276 17.982 1.00 12.48 ? 272 PRO A O 1 ATOM 2101 C CB . PRO A 1 272 ? 22.562 59.210 18.871 1.00 11.08 ? 272 PRO A CB 1 ATOM 2102 C CG . PRO A 1 272 ? 23.496 60.142 19.657 1.00 12.30 ? 272 PRO A CG 1 ATOM 2103 C CD . PRO A 1 272 ? 24.891 59.543 19.279 1.00 10.35 ? 272 PRO A CD 1 ATOM 2104 N N . HIS A 1 273 ? 23.625 56.796 16.860 1.00 10.68 ? 273 HIS A N 1 ATOM 2105 C CA . HIS A 1 273 ? 23.253 55.953 15.699 1.00 11.10 ? 273 HIS A CA 1 ATOM 2106 C C . HIS A 1 273 ? 24.196 54.781 15.501 1.00 9.57 ? 273 HIS A C 1 ATOM 2107 O O . HIS A 1 273 ? 24.238 54.185 14.427 1.00 10.77 ? 273 HIS A O 1 ATOM 2108 C CB . HIS A 1 273 ? 23.120 56.782 14.382 1.00 10.90 ? 273 HIS A CB 1 ATOM 2109 C CG . HIS A 1 273 ? 22.119 57.897 14.496 1.00 11.44 ? 273 HIS A CG 1 ATOM 2110 N ND1 . HIS A 1 273 ? 20.766 57.830 14.146 1.00 12.92 ? 273 HIS A ND1 1 ATOM 2111 C CD2 . HIS A 1 273 ? 22.317 59.142 14.987 1.00 8.29 ? 273 HIS A CD2 1 ATOM 2112 C CE1 . HIS A 1 273 ? 20.192 58.993 14.421 1.00 9.13 ? 273 HIS A CE1 1 ATOM 2113 N NE2 . HIS A 1 273 ? 21.104 59.802 14.935 1.00 14.25 ? 273 HIS A NE2 1 ATOM 2114 N N . THR A 1 274 ? 24.857 54.382 16.600 1.00 10.53 ? 274 THR A N 1 ATOM 2115 C CA . THR A 1 274 ? 25.761 53.235 16.480 1.00 10.47 ? 274 THR A CA 1 ATOM 2116 C C . THR A 1 274 ? 25.524 52.149 17.534 1.00 10.38 ? 274 THR A C 1 ATOM 2117 O O . THR A 1 274 ? 26.069 51.047 17.381 1.00 12.71 ? 274 THR A O 1 ATOM 2118 C CB . THR A 1 274 ? 27.257 53.640 16.454 1.00 10.82 ? 274 THR A CB 1 ATOM 2119 O OG1 . THR A 1 274 ? 27.524 54.578 17.505 1.00 10.70 ? 274 THR A OG1 1 ATOM 2120 C CG2 . THR A 1 274 ? 27.602 54.231 15.083 1.00 11.32 ? 274 THR A CG2 1 ATOM 2121 N N . CYS A 1 275 ? 24.725 52.390 18.592 1.00 11.38 ? 275 CYS A N 1 ATOM 2122 C CA . CYS A 1 275 ? 24.529 51.297 19.542 1.00 12.58 ? 275 CYS A CA 1 ATOM 2123 C C . CYS A 1 275 ? 23.371 50.378 19.126 1.00 11.76 ? 275 CYS A C 1 ATOM 2124 O O . CYS A 1 275 ? 23.321 49.229 19.591 1.00 13.23 ? 275 CYS A O 1 ATOM 2125 C CB . CYS A 1 275 ? 24.241 51.913 20.922 1.00 11.58 ? 275 CYS A CB 1 ATOM 2126 S SG . CYS A 1 275 ? 22.508 51.992 21.481 1.00 15.13 ? 275 CYS A SG 1 ATOM 2127 N N . GLY A 1 276 ? 22.482 50.844 18.263 1.00 11.31 ? 276 GLY A N 1 ATOM 2128 C CA . GLY A 1 276 ? 21.256 50.119 17.901 1.00 12.19 ? 276 GLY A CA 1 ATOM 2129 C C . GLY A 1 276 ? 20.344 51.053 17.163 1.00 12.20 ? 276 GLY A C 1 ATOM 2130 O O . GLY A 1 276 ? 20.718 52.229 16.904 1.00 12.40 ? 276 GLY A O 1 ATOM 2131 N N . PRO A 1 277 ? 19.102 50.626 16.849 1.00 11.00 ? 277 PRO A N 1 ATOM 2132 C CA . PRO A 1 277 ? 18.133 51.384 16.101 1.00 11.32 ? 277 PRO A CA 1 ATOM 2133 C C . PRO A 1 277 ? 17.459 52.583 16.691 1.00 11.90 ? 277 PRO A C 1 ATOM 2134 O O . PRO A 1 277 ? 16.884 53.367 15.927 1.00 12.19 ? 277 PRO A O 1 ATOM 2135 C CB . PRO A 1 277 ? 17.082 50.306 15.707 1.00 13.86 ? 277 PRO A CB 1 ATOM 2136 C CG . PRO A 1 277 ? 17.125 49.409 16.924 1.00 11.47 ? 277 PRO A CG 1 ATOM 2137 C CD . PRO A 1 277 ? 18.595 49.273 17.188 1.00 12.17 ? 277 PRO A CD 1 ATOM 2138 N N . ASP A 1 278 ? 17.508 52.698 18.010 1.00 13.20 ? 278 ASP A N 1 ATOM 2139 C CA . ASP A 1 278 ? 16.750 53.806 18.643 1.00 12.29 ? 278 ASP A CA 1 ATOM 2140 C C . ASP A 1 278 ? 17.709 54.871 19.216 1.00 12.90 ? 278 ASP A C 1 ATOM 2141 O O . ASP A 1 278 ? 18.294 54.679 20.279 1.00 12.88 ? 278 ASP A O 1 ATOM 2142 C CB . ASP A 1 278 ? 15.896 53.251 19.821 1.00 12.90 ? 278 ASP A CB 1 ATOM 2143 C CG . ASP A 1 278 ? 14.980 54.324 20.387 1.00 15.69 ? 278 ASP A CG 1 ATOM 2144 O OD1 . ASP A 1 278 ? 15.110 55.509 20.037 1.00 16.63 ? 278 ASP A OD1 1 ATOM 2145 O OD2 . ASP A 1 278 ? 14.107 53.973 21.211 1.00 18.05 ? 278 ASP A OD2 1 ATOM 2146 N N . PRO A 1 279 ? 17.838 56.001 18.506 1.00 13.76 ? 279 PRO A N 1 ATOM 2147 C CA . PRO A 1 279 ? 18.752 57.025 19.026 1.00 14.26 ? 279 PRO A CA 1 ATOM 2148 C C . PRO A 1 279 ? 18.425 57.635 20.354 1.00 13.19 ? 279 PRO A C 1 ATOM 2149 O O . PRO A 1 279 ? 19.299 58.096 21.059 1.00 14.29 ? 279 PRO A O 1 ATOM 2150 C CB . PRO A 1 279 ? 18.810 58.053 17.906 1.00 14.12 ? 279 PRO A CB 1 ATOM 2151 C CG . PRO A 1 279 ? 17.503 57.930 17.197 1.00 14.11 ? 279 PRO A CG 1 ATOM 2152 C CD . PRO A 1 279 ? 17.130 56.429 17.285 1.00 13.29 ? 279 PRO A CD 1 ATOM 2153 N N . LYS A 1 280 ? 17.136 57.648 20.725 1.00 12.88 ? 280 LYS A N 1 ATOM 2154 C CA . LYS A 1 280 ? 16.759 58.196 22.026 1.00 14.80 ? 280 LYS A CA 1 ATOM 2155 C C . LYS A 1 280 ? 17.387 57.322 23.122 1.00 13.14 ? 280 LYS A C 1 ATOM 2156 O O . LYS A 1 280 ? 17.752 57.821 24.193 1.00 16.45 ? 280 LYS A O 1 ATOM 2157 C CB . LYS A 1 280 ? 15.232 58.222 22.130 1.00 16.31 ? 280 LYS A CB 1 ATOM 2158 C CG . LYS A 1 280 ? 14.714 58.684 23.461 1.00 17.55 ? 280 LYS A CG 1 ATOM 2159 C CD . LYS A 1 280 ? 13.181 58.716 23.388 1.00 23.31 ? 280 LYS A CD 1 ATOM 2160 C CE . LYS A 1 280 ? 12.611 59.575 24.502 1.00 34.10 ? 280 LYS A CE 1 ATOM 2161 N NZ . LYS A 1 280 ? 11.117 59.666 24.386 1.00 37.53 ? 280 LYS A NZ 1 ATOM 2162 N N . VAL A 1 281 ? 17.504 56.017 22.886 1.00 13.64 ? 281 VAL A N 1 ATOM 2163 C CA . VAL A 1 281 ? 18.168 55.124 23.829 1.00 14.47 ? 281 VAL A CA 1 ATOM 2164 C C . VAL A 1 281 ? 19.711 55.218 23.716 1.00 14.09 ? 281 VAL A C 1 ATOM 2165 O O . VAL A 1 281 ? 20.419 55.404 24.716 1.00 12.88 ? 281 VAL A O 1 ATOM 2166 C CB . VAL A 1 281 ? 17.757 53.621 23.609 1.00 14.79 ? 281 VAL A CB 1 ATOM 2167 C CG1 . VAL A 1 281 ? 18.513 52.696 24.571 1.00 17.15 ? 281 VAL A CG1 1 ATOM 2168 C CG2 . VAL A 1 281 ? 16.215 53.533 23.845 1.00 15.41 ? 281 VAL A CG2 1 ATOM 2169 N N . CYS A 1 282 ? 20.236 55.095 22.483 1.00 12.97 ? 282 CYS A N 1 ATOM 2170 C CA . CYS A 1 282 ? 21.699 55.121 22.325 1.00 12.18 ? 282 CYS A CA 1 ATOM 2171 C C . CYS A 1 282 ? 22.342 56.439 22.821 1.00 10.83 ? 282 CYS A C 1 ATOM 2172 O O . CYS A 1 282 ? 23.457 56.397 23.351 1.00 11.80 ? 282 CYS A O 1 ATOM 2173 C CB . CYS A 1 282 ? 22.061 54.930 20.850 1.00 12.65 ? 282 CYS A CB 1 ATOM 2174 S SG . CYS A 1 282 ? 21.629 53.303 20.183 1.00 14.16 ? 282 CYS A SG 1 ATOM 2175 N N . CYS A 1 283 ? 21.646 57.564 22.659 1.00 11.59 ? 283 CYS A N 1 ATOM 2176 C CA . CYS A 1 283 ? 22.223 58.808 23.148 1.00 12.30 ? 283 CYS A CA 1 ATOM 2177 C C . CYS A 1 283 ? 22.536 58.766 24.673 1.00 11.68 ? 283 CYS A C 1 ATOM 2178 O O . CYS A 1 283 ? 23.420 59.462 25.153 1.00 11.79 ? 283 CYS A O 1 ATOM 2179 C CB . CYS A 1 283 ? 21.265 59.942 22.788 1.00 13.14 ? 283 CYS A CB 1 ATOM 2180 S SG . CYS A 1 283 ? 22.060 61.566 22.923 1.00 14.53 ? 283 CYS A SG 1 ATOM 2181 N N . GLN A 1 284 ? 21.777 57.940 25.447 1.00 11.95 ? 284 GLN A N 1 ATOM 2182 C CA . GLN A 1 284 ? 22.016 57.799 26.861 1.00 13.69 ? 284 GLN A CA 1 ATOM 2183 C C . GLN A 1 284 ? 23.289 57.057 27.181 1.00 12.29 ? 284 GLN A C 1 ATOM 2184 O O . GLN A 1 284 ? 23.655 56.961 28.355 1.00 14.16 ? 284 GLN A O 1 ATOM 2185 C CB . GLN A 1 284 ? 20.814 57.070 27.543 1.00 13.71 ? 284 GLN A CB 1 ATOM 2186 C CG . GLN A 1 284 ? 19.510 57.821 27.323 1.00 15.09 ? 284 GLN A CG 1 ATOM 2187 C CD . GLN A 1 284 ? 18.306 57.028 27.855 1.00 14.28 ? 284 GLN A CD 1 ATOM 2188 O OE1 . GLN A 1 284 ? 18.312 56.597 29.006 1.00 19.08 ? 284 GLN A OE1 1 ATOM 2189 N NE2 . GLN A 1 284 ? 17.321 56.844 27.012 1.00 16.61 ? 284 GLN A NE2 1 ATOM 2190 N N . PHE A 1 285 ? 23.958 56.524 26.141 1.00 10.88 ? 285 PHE A N 1 ATOM 2191 C CA . PHE A 1 285 ? 25.178 55.798 26.355 1.00 11.25 ? 285 PHE A CA 1 ATOM 2192 C C . PHE A 1 285 ? 26.371 56.553 25.754 1.00 10.97 ? 285 PHE A C 1 ATOM 2193 O O . PHE A 1 285 ? 27.435 55.949 25.516 1.00 11.87 ? 285 PHE A O 1 ATOM 2194 C CB . PHE A 1 285 ? 25.045 54.329 25.891 1.00 11.79 ? 285 PHE A CB 1 ATOM 2195 C CG . PHE A 1 285 ? 24.036 53.562 26.738 1.00 11.68 ? 285 PHE A CG 1 ATOM 2196 C CD1 . PHE A 1 285 ? 24.447 52.959 27.907 1.00 13.68 ? 285 PHE A CD1 1 ATOM 2197 C CD2 . PHE A 1 285 ? 22.688 53.543 26.380 1.00 13.62 ? 285 PHE A CD2 1 ATOM 2198 C CE1 . PHE A 1 285 ? 23.506 52.310 28.771 1.00 13.77 ? 285 PHE A CE1 1 ATOM 2199 C CE2 . PHE A 1 285 ? 21.714 52.893 27.244 1.00 15.43 ? 285 PHE A CE2 1 ATOM 2200 C CZ . PHE A 1 285 ? 22.157 52.282 28.435 1.00 14.99 ? 285 PHE A CZ 1 ATOM 2201 N N . ASP A 1 286 ? 26.147 57.838 25.497 1.00 11.83 ? 286 ASP A N 1 ATOM 2202 C CA . ASP A 1 286 ? 27.259 58.745 25.104 1.00 10.58 ? 286 ASP A CA 1 ATOM 2203 C C . ASP A 1 286 ? 27.508 59.551 26.397 1.00 9.75 ? 286 ASP A C 1 ATOM 2204 O O . ASP A 1 286 ? 26.811 60.558 26.607 1.00 12.30 ? 286 ASP A O 1 ATOM 2205 C CB . ASP A 1 286 ? 26.844 59.641 23.966 1.00 10.44 ? 286 ASP A CB 1 ATOM 2206 C CG . ASP A 1 286 ? 27.969 60.536 23.457 1.00 9.80 ? 286 ASP A CG 1 ATOM 2207 O OD1 . ASP A 1 286 ? 28.995 60.612 24.165 1.00 10.77 ? 286 ASP A OD1 1 ATOM 2208 O OD2 . ASP A 1 286 ? 27.786 61.175 22.401 1.00 11.17 ? 286 ASP A OD2 1 ATOM 2209 N N . PHE A 1 287 ? 28.482 59.149 27.191 1.00 9.49 ? 287 PHE A N 1 ATOM 2210 C CA . PHE A 1 287 ? 28.621 59.760 28.506 1.00 10.84 ? 287 PHE A CA 1 ATOM 2211 C C . PHE A 1 287 ? 29.196 61.149 28.485 1.00 12.55 ? 287 PHE A C 1 ATOM 2212 O O . PHE A 1 287 ? 29.289 61.793 29.530 1.00 13.82 ? 287 PHE A O 1 ATOM 2213 C CB . PHE A 1 287 ? 29.358 58.797 29.419 1.00 11.49 ? 287 PHE A CB 1 ATOM 2214 C CG . PHE A 1 287 ? 28.546 57.528 29.663 1.00 10.41 ? 287 PHE A CG 1 ATOM 2215 C CD1 . PHE A 1 287 ? 28.716 56.385 28.873 1.00 12.33 ? 287 PHE A CD1 1 ATOM 2216 C CD2 . PHE A 1 287 ? 27.553 57.510 30.678 1.00 12.73 ? 287 PHE A CD2 1 ATOM 2217 C CE1 . PHE A 1 287 ? 27.914 55.240 29.055 1.00 12.93 ? 287 PHE A CE1 1 ATOM 2218 C CE2 . PHE A 1 287 ? 26.757 56.365 30.880 1.00 11.98 ? 287 PHE A CE2 1 ATOM 2219 C CZ . PHE A 1 287 ? 26.915 55.233 30.086 1.00 12.03 ? 287 PHE A CZ 1 ATOM 2220 N N . LYS A 1 288 ? 29.554 61.647 27.287 1.00 11.98 ? 288 LYS A N 1 ATOM 2221 C CA . LYS A 1 288 ? 30.006 63.047 27.206 1.00 12.08 ? 288 LYS A CA 1 ATOM 2222 C C . LYS A 1 288 ? 28.803 63.972 27.131 1.00 13.35 ? 288 LYS A C 1 ATOM 2223 O O . LYS A 1 288 ? 28.986 65.194 27.220 1.00 14.25 ? 288 LYS A O 1 ATOM 2224 C CB . LYS A 1 288 ? 30.912 63.236 25.911 1.00 12.14 ? 288 LYS A CB 1 ATOM 2225 C CG . LYS A 1 288 ? 31.696 64.566 25.969 1.00 11.63 ? 288 LYS A CG 1 ATOM 2226 C CD . LYS A 1 288 ? 32.554 64.706 24.706 1.00 10.76 ? 288 LYS A CD 1 ATOM 2227 C CE . LYS A 1 288 ? 33.384 65.988 24.881 1.00 11.52 ? 288 LYS A CE 1 ATOM 2228 N NZ . LYS A 1 288 ? 34.389 66.161 23.722 1.00 14.06 ? 288 LYS A NZ 1 ATOM 2229 N N . ARG A 1 289 ? 27.554 63.458 27.073 1.00 13.28 ? 289 ARG A N 1 ATOM 2230 C CA . ARG A 1 289 ? 26.413 64.352 26.951 1.00 14.01 ? 289 ARG A CA 1 ATOM 2231 C C . ARG A 1 289 ? 25.691 64.671 28.305 1.00 19.27 ? 289 ARG A C 1 ATOM 2232 O O . ARG A 1 289 ? 24.479 64.836 28.290 1.00 19.56 ? 289 ARG A O 1 ATOM 2233 C CB . ARG A 1 289 ? 25.390 63.766 25.963 1.00 14.15 ? 289 ARG A CB 1 ATOM 2234 C CG . ARG A 1 289 ? 26.007 63.570 24.571 1.00 12.77 ? 289 ARG A CG 1 ATOM 2235 C CD . ARG A 1 289 ? 25.000 63.181 23.585 1.00 15.20 ? 289 ARG A CD 1 ATOM 2236 N NE . ARG A 1 289 ? 25.551 62.916 22.250 1.00 12.26 ? 289 ARG A NE 1 ATOM 2237 C CZ . ARG A 1 289 ? 25.131 63.468 21.124 1.00 13.68 ? 289 ARG A CZ 1 ATOM 2238 N NH1 . ARG A 1 289 ? 24.160 64.381 21.107 1.00 15.36 ? 289 ARG A NH1 1 ATOM 2239 N NH2 . ARG A 1 289 ? 25.579 62.976 19.979 1.00 13.05 ? 289 ARG A NH2 1 ATOM 2240 N N . MET A 1 290 ? 26.384 64.777 29.445 1.00 25.28 ? 290 MET A N 1 ATOM 2241 C CA . MET A 1 290 ? 25.601 65.067 30.686 1.00 30.83 ? 290 MET A CA 1 ATOM 2242 C C . MET A 1 290 ? 25.477 66.559 31.154 1.00 33.69 ? 290 MET A C 1 ATOM 2243 O O . MET A 1 290 ? 24.691 66.841 32.106 1.00 36.51 ? 290 MET A O 1 ATOM 2244 C CB . MET A 1 290 ? 26.008 64.117 31.871 1.00 28.71 ? 290 MET A CB 1 ATOM 2245 C CG . MET A 1 290 ? 25.787 62.643 31.584 1.00 32.92 ? 290 MET A CG 1 ATOM 2246 S SD . MET A 1 290 ? 26.257 61.421 32.887 1.00 31.97 ? 290 MET A SD 1 ATOM 2247 C CE . MET A 1 290 ? 28.103 61.311 32.629 1.00 33.23 ? 290 MET A CE 1 ATOM 2248 N N . GLY A 1 291 ? 26.192 67.497 30.491 1.00 30.83 ? 291 GLY A N 1 ATOM 2249 C CA . GLY A 1 291 ? 26.120 68.929 30.816 1.00 27.70 ? 291 GLY A CA 1 ATOM 2250 C C . GLY A 1 291 ? 27.429 69.773 30.864 1.00 27.01 ? 291 GLY A C 1 ATOM 2251 O O . GLY A 1 291 ? 27.599 70.835 30.218 1.00 26.29 ? 291 GLY A O 1 ATOM 2252 N N . SER A 1 292 ? 28.385 69.282 31.644 1.00 21.59 ? 292 SER A N 1 ATOM 2253 C CA . SER A 1 292 ? 29.666 69.943 31.829 1.00 16.57 ? 292 SER A CA 1 ATOM 2254 C C . SER A 1 292 ? 30.520 70.069 30.556 1.00 15.72 ? 292 SER A C 1 ATOM 2255 O O . SER A 1 292 ? 31.433 70.893 30.510 1.00 15.49 ? 292 SER A O 1 ATOM 2256 C CB . SER A 1 292 ? 30.430 69.208 32.915 1.00 19.75 ? 292 SER A CB 1 ATOM 2257 O OG . SER A 1 292 ? 30.863 67.947 32.409 1.00 20.77 ? 292 SER A OG 1 ATOM 2258 N N . PHE A 1 293 ? 30.253 69.236 29.550 1.00 13.75 ? 293 PHE A N 1 ATOM 2259 C CA . PHE A 1 293 ? 30.940 69.295 28.261 1.00 13.93 ? 293 PHE A CA 1 ATOM 2260 C C . PHE A 1 293 ? 30.192 70.141 27.230 1.00 12.91 ? 293 PHE A C 1 ATOM 2261 O O . PHE A 1 293 ? 30.616 70.205 26.066 1.00 14.67 ? 293 PHE A O 1 ATOM 2262 C CB . PHE A 1 293 ? 31.105 67.850 27.684 1.00 14.35 ? 293 PHE A CB 1 ATOM 2263 C CG . PHE A 1 293 ? 32.013 66.984 28.501 1.00 12.25 ? 293 PHE A CG 1 ATOM 2264 C CD1 . PHE A 1 293 ? 31.488 66.061 29.383 1.00 14.90 ? 293 PHE A CD1 1 ATOM 2265 C CD2 . PHE A 1 293 ? 33.398 67.100 28.363 1.00 12.38 ? 293 PHE A CD2 1 ATOM 2266 C CE1 . PHE A 1 293 ? 32.350 65.223 30.143 1.00 14.62 ? 293 PHE A CE1 1 ATOM 2267 C CE2 . PHE A 1 293 ? 34.281 66.281 29.110 1.00 14.79 ? 293 PHE A CE2 1 ATOM 2268 C CZ . PHE A 1 293 ? 33.735 65.353 29.995 1.00 15.06 ? 293 PHE A CZ 1 ATOM 2269 N N . GLY A 1 294 ? 29.043 70.689 27.629 1.00 14.13 ? 294 GLY A N 1 ATOM 2270 C CA . GLY A 1 294 ? 28.290 71.495 26.666 1.00 17.67 ? 294 GLY A CA 1 ATOM 2271 C C . GLY A 1 294 ? 27.575 70.693 25.579 1.00 15.29 ? 294 GLY A C 1 ATOM 2272 O O . GLY A 1 294 ? 27.312 71.178 24.474 1.00 18.36 ? 294 GLY A O 1 ATOM 2273 N N . LEU A 1 295 ? 27.269 69.428 25.864 1.00 15.61 ? 295 LEU A N 1 ATOM 2274 C CA . LEU A 1 295 ? 26.556 68.591 24.913 1.00 14.63 ? 295 LEU A CA 1 ATOM 2275 C C . LEU A 1 295 ? 25.316 68.034 25.623 1.00 16.25 ? 295 LEU A C 1 ATOM 2276 O O . LEU A 1 295 ? 25.285 67.951 26.847 1.00 17.22 ? 295 LEU A O 1 ATOM 2277 C CB . LEU A 1 295 ? 27.453 67.431 24.440 1.00 15.40 ? 295 LEU A CB 1 ATOM 2278 C CG . LEU A 1 295 ? 28.755 67.903 23.740 1.00 16.02 ? 295 LEU A CG 1 ATOM 2279 C CD1 . LEU A 1 295 ? 29.666 66.660 23.534 1.00 16.53 ? 295 LEU A CD1 1 ATOM 2280 C CD2 . LEU A 1 295 ? 28.441 68.527 22.373 1.00 17.83 ? 295 LEU A CD2 1 ATOM 2281 N N . SER A 1 296 ? 24.311 67.709 24.819 1.00 14.86 ? 296 SER A N 1 ATOM 2282 C CA . SER A 1 296 ? 23.059 67.138 25.360 1.00 17.43 ? 296 SER A CA 1 ATOM 2283 C C . SER A 1 296 ? 22.461 66.202 24.312 1.00 18.48 ? 296 SER A C 1 ATOM 2284 O O . SER A 1 296 ? 22.971 66.094 23.208 1.00 16.23 ? 296 SER A O 1 ATOM 2285 C CB . SER A 1 296 ? 22.074 68.281 25.740 1.00 17.34 ? 296 SER A CB 1 ATOM 2286 O OG . SER A 1 296 ? 21.838 69.134 24.648 1.00 21.73 ? 296 SER A OG 1 ATOM 2287 N N . CYS A 1 297 ? 21.375 65.506 24.692 1.00 16.47 ? 297 CYS A N 1 ATOM 2288 C CA . CYS A 1 297 ? 20.677 64.574 23.816 1.00 17.39 ? 297 CYS A CA 1 ATOM 2289 C C . CYS A 1 297 ? 19.440 65.279 23.247 1.00 18.90 ? 297 CYS A C 1 ATOM 2290 O O . CYS A 1 297 ? 18.540 65.697 24.025 1.00 19.32 ? 297 CYS A O 1 ATOM 2291 C CB . CYS A 1 297 ? 20.231 63.334 24.624 1.00 18.13 ? 297 CYS A CB 1 ATOM 2292 S SG . CYS A 1 297 ? 21.648 62.191 24.885 1.00 18.77 ? 297 CYS A SG 1 ATOM 2293 N N . PRO A 1 298 ? 19.330 65.396 21.936 1.00 18.57 ? 298 PRO A N 1 ATOM 2294 C CA . PRO A 1 298 ? 18.153 66.069 21.374 1.00 20.49 ? 298 PRO A CA 1 ATOM 2295 C C . PRO A 1 298 ? 16.864 65.282 21.562 1.00 20.23 ? 298 PRO A C 1 ATOM 2296 O O . PRO A 1 298 ? 15.769 65.870 21.448 1.00 20.67 ? 298 PRO A O 1 ATOM 2297 C CB . PRO A 1 298 ? 18.499 66.300 19.903 1.00 23.38 ? 298 PRO A CB 1 ATOM 2298 C CG . PRO A 1 298 ? 19.718 65.437 19.616 1.00 23.17 ? 298 PRO A CG 1 ATOM 2299 C CD . PRO A 1 298 ? 20.420 65.230 20.928 1.00 16.58 ? 298 PRO A CD 1 ATOM 2300 N N . TRP A 1 299 ? 16.973 64.000 21.898 1.00 17.60 ? 299 TRP A N 1 ATOM 2301 C CA . TRP A 1 299 ? 15.766 63.161 22.116 1.00 17.28 ? 299 TRP A CA 1 ATOM 2302 C C . TRP A 1 299 ? 15.268 63.381 23.548 1.00 19.70 ? 299 TRP A C 1 ATOM 2303 O O . TRP A 1 299 ? 14.307 62.727 23.992 1.00 20.63 ? 299 TRP A O 1 ATOM 2304 C CB . TRP A 1 299 ? 16.082 61.668 21.834 1.00 16.57 ? 299 TRP A CB 1 ATOM 2305 C CG . TRP A 1 299 ? 16.439 61.478 20.409 1.00 16.51 ? 299 TRP A CG 1 ATOM 2306 C CD1 . TRP A 1 299 ? 15.608 61.278 19.388 1.00 16.79 ? 299 TRP A CD1 1 ATOM 2307 C CD2 . TRP A 1 299 ? 17.768 61.597 19.855 1.00 14.88 ? 299 TRP A CD2 1 ATOM 2308 N NE1 . TRP A 1 299 ? 16.308 61.255 18.181 1.00 18.60 ? 299 TRP A NE1 1 ATOM 2309 C CE2 . TRP A 1 299 ? 17.636 61.458 18.452 1.00 17.74 ? 299 TRP A CE2 1 ATOM 2310 C CE3 . TRP A 1 299 ? 19.030 61.807 20.414 1.00 15.02 ? 299 TRP A CE3 1 ATOM 2311 C CZ2 . TRP A 1 299 ? 18.728 61.530 17.579 1.00 15.69 ? 299 TRP A CZ2 1 ATOM 2312 C CZ3 . TRP A 1 299 ? 20.107 61.881 19.531 1.00 14.76 ? 299 TRP A CZ3 1 ATOM 2313 C CH2 . TRP A 1 299 ? 19.937 61.747 18.145 1.00 14.00 ? 299 TRP A CH2 1 ATOM 2314 N N . LYS A 1 300 ? 15.962 64.236 24.303 1.00 19.51 ? 300 LYS A N 1 ATOM 2315 C CA . LYS A 1 300 ? 15.496 64.676 25.648 1.00 20.78 ? 300 LYS A CA 1 ATOM 2316 C C . LYS A 1 300 ? 15.677 63.745 26.833 1.00 21.69 ? 300 LYS A C 1 ATOM 2317 O O . LYS A 1 300 ? 15.147 64.015 27.947 1.00 22.10 ? 300 LYS A O 1 ATOM 2318 C CB . LYS A 1 300 ? 14.024 65.124 25.563 1.00 24.68 ? 300 LYS A CB 1 ATOM 2319 C CG . LYS A 1 300 ? 13.834 66.288 24.662 1.00 23.77 ? 300 LYS A CG 1 ATOM 2320 C CD . LYS A 1 300 ? 12.325 66.583 24.462 1.00 30.89 ? 300 LYS A CD 1 ATOM 2321 C CE . LYS A 1 300 ? 12.095 67.871 23.707 1.00 34.39 ? 300 LYS A CE 1 ATOM 2322 N NZ . LYS A 1 300 ? 12.849 67.914 22.427 1.00 37.90 ? 300 LYS A NZ 1 ATOM 2323 N N . VAL A 1 301 ? 16.374 62.629 26.664 1.00 21.58 ? 301 VAL A N 1 ATOM 2324 C CA . VAL A 1 301 ? 16.633 61.775 27.787 1.00 19.51 ? 301 VAL A CA 1 ATOM 2325 C C . VAL A 1 301 ? 18.170 61.785 27.885 1.00 17.97 ? 301 VAL A C 1 ATOM 2326 O O . VAL A 1 301 ? 18.854 61.320 26.976 1.00 21.02 ? 301 VAL A O 1 ATOM 2327 C CB . VAL A 1 301 ? 16.122 60.326 27.589 1.00 20.99 ? 301 VAL A CB 1 ATOM 2328 C CG1 . VAL A 1 301 ? 16.398 59.557 28.867 1.00 21.34 ? 301 VAL A CG1 1 ATOM 2329 C CG2 . VAL A 1 301 ? 14.571 60.328 27.232 1.00 25.89 ? 301 VAL A CG2 1 ATOM 2330 N N . PRO A 1 302 ? 18.727 62.288 28.968 1.00 16.22 ? 302 PRO A N 1 ATOM 2331 C CA . PRO A 1 302 ? 20.171 62.350 29.099 1.00 17.73 ? 302 PRO A CA 1 ATOM 2332 C C . PRO A 1 302 ? 20.815 61.085 29.583 1.00 17.50 ? 302 PRO A C 1 ATOM 2333 O O . PRO A 1 302 ? 20.177 60.188 30.063 1.00 17.77 ? 302 PRO A O 1 ATOM 2334 C CB . PRO A 1 302 ? 20.363 63.450 30.134 1.00 20.00 ? 302 PRO A CB 1 ATOM 2335 C CG . PRO A 1 302 ? 19.182 63.233 31.071 1.00 21.48 ? 302 PRO A CG 1 ATOM 2336 C CD . PRO A 1 302 ? 18.046 62.963 30.109 1.00 17.87 ? 302 PRO A CD 1 ATOM 2337 N N . PRO A 1 303 ? 22.118 60.957 29.346 1.00 14.97 ? 303 PRO A N 1 ATOM 2338 C CA . PRO A 1 303 ? 22.788 59.775 29.876 1.00 14.31 ? 303 PRO A CA 1 ATOM 2339 C C . PRO A 1 303 ? 22.815 59.939 31.405 1.00 19.00 ? 303 PRO A C 1 ATOM 2340 O O . PRO A 1 303 ? 22.734 61.066 31.925 1.00 18.29 ? 303 PRO A O 1 ATOM 2341 C CB . PRO A 1 303 ? 24.246 59.886 29.374 1.00 16.26 ? 303 PRO A CB 1 ATOM 2342 C CG . PRO A 1 303 ? 24.319 61.221 28.615 1.00 19.50 ? 303 PRO A CG 1 ATOM 2343 C CD . PRO A 1 303 ? 23.031 61.937 28.709 1.00 16.58 ? 303 PRO A CD 1 ATOM 2344 N N . ARG A 1 304 ? 22.921 58.817 32.097 1.00 18.43 ? 304 ARG A N 1 ATOM 2345 C CA . ARG A 1 304 ? 23.077 58.830 33.545 1.00 19.25 ? 304 ARG A CA 1 ATOM 2346 C C . ARG A 1 304 ? 24.265 57.978 33.930 1.00 14.31 ? 304 ARG A C 1 ATOM 2347 O O . ARG A 1 304 ? 24.496 56.855 33.346 1.00 16.60 ? 304 ARG A O 1 ATOM 2348 C CB . ARG A 1 304 ? 21.809 58.312 34.236 1.00 23.47 ? 304 ARG A CB 1 ATOM 2349 C CG . ARG A 1 304 ? 20.694 59.361 34.184 1.00 27.81 ? 304 ARG A CG 1 ATOM 2350 C CD . ARG A 1 304 ? 19.485 58.913 34.942 1.00 31.41 ? 304 ARG A CD 1 ATOM 2351 N NE . ARG A 1 304 ? 18.699 57.948 34.185 1.00 33.75 ? 304 ARG A NE 1 ATOM 2352 C CZ . ARG A 1 304 ? 18.606 56.665 34.521 1.00 37.50 ? 304 ARG A CZ 1 ATOM 2353 N NH1 . ARG A 1 304 ? 19.254 56.217 35.597 1.00 39.83 ? 304 ARG A NH1 1 ATOM 2354 N NH2 . ARG A 1 304 ? 17.856 55.836 33.804 1.00 39.94 ? 304 ARG A NH2 1 ATOM 2355 N N . THR A 1 305 ? 25.057 58.495 34.862 1.00 16.64 ? 305 THR A N 1 ATOM 2356 C CA . THR A 1 305 ? 26.220 57.754 35.343 1.00 15.58 ? 305 THR A CA 1 ATOM 2357 C C . THR A 1 305 ? 25.840 56.356 35.760 1.00 14.88 ? 305 THR A C 1 ATOM 2358 O O . THR A 1 305 ? 24.791 56.188 36.479 1.00 17.34 ? 305 THR A O 1 ATOM 2359 C CB . THR A 1 305 ? 26.880 58.494 36.528 1.00 16.80 ? 305 THR A CB 1 ATOM 2360 O OG1 . THR A 1 305 ? 27.343 59.763 36.037 1.00 20.99 ? 305 THR A OG1 1 ATOM 2361 C CG2 . THR A 1 305 ? 27.959 57.727 37.173 1.00 17.72 ? 305 THR A CG2 1 ATOM 2362 N N . ILE A 1 306 ? 26.592 55.341 35.364 1.00 12.75 ? 306 ILE A N 1 ATOM 2363 C CA . ILE A 1 306 ? 26.273 53.969 35.745 1.00 13.47 ? 306 ILE A CA 1 ATOM 2364 C C . ILE A 1 306 ? 26.705 53.747 37.188 1.00 15.62 ? 306 ILE A C 1 ATOM 2365 O O . ILE A 1 306 ? 27.812 54.093 37.609 1.00 16.77 ? 306 ILE A O 1 ATOM 2366 C CB . ILE A 1 306 ? 26.982 52.967 34.792 1.00 13.03 ? 306 ILE A CB 1 ATOM 2367 C CG1 . ILE A 1 306 ? 26.617 53.227 33.300 1.00 12.79 ? 306 ILE A CG1 1 ATOM 2368 C CG2 . ILE A 1 306 ? 26.539 51.485 35.158 1.00 13.47 ? 306 ILE A CG2 1 ATOM 2369 C CD1 . ILE A 1 306 ? 25.085 53.235 32.982 1.00 14.12 ? 306 ILE A CD1 1 ATOM 2370 N N . SER A 1 307 ? 25.816 53.074 37.937 1.00 17.64 ? 307 SER A N 1 ATOM 2371 C CA . SER A 1 307 ? 26.023 52.768 39.368 1.00 17.55 ? 307 SER A CA 1 ATOM 2372 C C . SER A 1 307 ? 25.525 51.353 39.626 1.00 18.16 ? 307 SER A C 1 ATOM 2373 O O . SER A 1 307 ? 24.777 50.782 38.796 1.00 15.77 ? 307 SER A O 1 ATOM 2374 C CB . SER A 1 307 ? 25.141 53.679 40.244 1.00 18.48 ? 307 SER A CB 1 ATOM 2375 O OG . SER A 1 307 ? 23.750 53.390 40.078 1.00 18.67 ? 307 SER A OG 1 ATOM 2376 N N . ASP A 1 308 ? 25.801 50.847 40.833 1.00 20.01 ? 308 ASP A N 1 ATOM 2377 C CA . ASP A 1 308 ? 25.274 49.505 41.134 1.00 22.46 ? 308 ASP A CA 1 ATOM 2378 C C . ASP A 1 308 ? 23.728 49.496 41.201 1.00 20.35 ? 308 ASP A C 1 ATOM 2379 O O . ASP A 1 308 ? 23.130 48.441 40.917 1.00 18.06 ? 308 ASP A O 1 ATOM 2380 C CB . ASP A 1 308 ? 25.870 48.935 42.433 1.00 25.45 ? 308 ASP A CB 1 ATOM 2381 C CG . ASP A 1 308 ? 27.395 48.722 42.370 1.00 31.64 ? 308 ASP A CG 1 ATOM 2382 O OD1 . ASP A 1 308 ? 28.036 48.867 41.303 1.00 32.39 ? 308 ASP A OD1 1 ATOM 2383 O OD2 . ASP A 1 308 ? 28.000 48.378 43.408 1.00 37.27 ? 308 ASP A OD2 1 ATOM 2384 N N . GLN A 1 309 ? 23.061 50.623 41.459 1.00 20.83 ? 309 GLN A N 1 ATOM 2385 C CA . GLN A 1 309 ? 21.579 50.677 41.523 1.00 21.06 ? 309 GLN A CA 1 ATOM 2386 C C . GLN A 1 309 ? 20.906 50.807 40.180 1.00 23.28 ? 309 GLN A C 1 ATOM 2387 O O . GLN A 1 309 ? 19.682 50.553 40.059 1.00 21.26 ? 309 GLN A O 1 ATOM 2388 C CB . GLN A 1 309 ? 21.062 51.854 42.428 1.00 17.61 ? 309 GLN A CB 1 ATOM 2389 C CG . GLN A 1 309 ? 21.465 51.754 43.900 1.00 22.65 ? 309 GLN A CG 1 ATOM 2390 C CD . GLN A 1 309 ? 22.966 51.896 44.072 1.00 24.56 ? 309 GLN A CD 1 ATOM 2391 O OE1 . GLN A 1 309 ? 23.563 52.834 43.516 1.00 23.15 ? 309 GLN A OE1 1 ATOM 2392 N NE2 . GLN A 1 309 ? 23.597 50.965 44.817 1.00 25.22 ? 309 GLN A NE2 1 ATOM 2393 N N . ASN A 1 310 ? 21.653 51.197 39.137 1.00 18.11 ? 310 ASN A N 1 ATOM 2394 C CA . ASN A 1 310 ? 20.951 51.341 37.861 1.00 16.54 ? 310 ASN A CA 1 ATOM 2395 C C . ASN A 1 310 ? 21.588 50.435 36.772 1.00 14.60 ? 310 ASN A C 1 ATOM 2396 O O . ASN A 1 310 ? 21.046 50.340 35.701 1.00 15.47 ? 310 ASN A O 1 ATOM 2397 C CB . ASN A 1 310 ? 20.919 52.813 37.413 1.00 18.09 ? 310 ASN A CB 1 ATOM 2398 C CG . ASN A 1 310 ? 22.294 53.356 37.035 1.00 16.96 ? 310 ASN A CG 1 ATOM 2399 O OD1 . ASN A 1 310 ? 23.218 52.600 36.766 1.00 18.00 ? 310 ASN A OD1 1 ATOM 2400 N ND2 . ASN A 1 310 ? 22.409 54.662 37.040 1.00 19.46 ? 310 ASN A ND2 1 ATOM 2401 N N . VAL A 1 311 ? 22.671 49.758 37.105 1.00 14.08 ? 311 VAL A N 1 ATOM 2402 C CA . VAL A 1 311 ? 23.396 49.032 36.001 1.00 14.80 ? 311 VAL A CA 1 ATOM 2403 C C . VAL A 1 311 ? 22.548 47.930 35.412 1.00 17.93 ? 311 VAL A C 1 ATOM 2404 O O . VAL A 1 311 ? 22.650 47.666 34.222 1.00 16.33 ? 311 VAL A O 1 ATOM 2405 C CB . VAL A 1 311 ? 24.768 48.525 36.464 1.00 12.75 ? 311 VAL A CB 1 ATOM 2406 C CG1 . VAL A 1 311 ? 24.646 47.429 37.536 1.00 17.99 ? 311 VAL A CG1 1 ATOM 2407 C CG2 . VAL A 1 311 ? 25.619 48.005 35.230 1.00 15.88 ? 311 VAL A CG2 1 ATOM 2408 N N . ALA A 1 312 ? 21.682 47.285 36.196 1.00 15.92 ? 312 ALA A N 1 ATOM 2409 C CA . ALA A 1 312 ? 20.877 46.233 35.565 1.00 15.02 ? 312 ALA A CA 1 ATOM 2410 C C . ALA A 1 312 ? 19.861 46.781 34.594 1.00 16.07 ? 312 ALA A C 1 ATOM 2411 O O . ALA A 1 312 ? 19.723 46.239 33.480 1.00 16.73 ? 312 ALA A O 1 ATOM 2412 C CB . ALA A 1 312 ? 20.135 45.314 36.703 1.00 17.60 ? 312 ALA A CB 1 ATOM 2413 N N . ALA A 1 313 ? 19.175 47.881 34.901 1.00 15.33 ? 313 ALA A N 1 ATOM 2414 C CA . ALA A 1 313 ? 18.175 48.466 34.015 1.00 18.36 ? 313 ALA A CA 1 ATOM 2415 C C . ALA A 1 313 ? 18.888 49.072 32.793 1.00 18.67 ? 313 ALA A C 1 ATOM 2416 O O . ALA A 1 313 ? 18.382 48.987 31.694 1.00 17.48 ? 313 ALA A O 1 ATOM 2417 C CB . ALA A 1 313 ? 17.364 49.572 34.738 1.00 17.13 ? 313 ALA A CB 1 ATOM 2418 N N . ARG A 1 314 ? 20.021 49.738 33.022 1.00 16.83 ? 314 ARG A N 1 ATOM 2419 C CA . ARG A 1 314 ? 20.782 50.361 31.907 1.00 16.14 ? 314 ARG A CA 1 ATOM 2420 C C . ARG A 1 314 ? 21.305 49.230 31.011 1.00 14.81 ? 314 ARG A C 1 ATOM 2421 O O . ARG A 1 314 ? 21.233 49.377 29.790 1.00 15.47 ? 314 ARG A O 1 ATOM 2422 C CB . ARG A 1 314 ? 21.971 51.160 32.489 1.00 14.08 ? 314 ARG A CB 1 ATOM 2423 C CG . ARG A 1 314 ? 21.642 52.363 33.370 1.00 16.11 ? 314 ARG A CG 1 ATOM 2424 C CD . ARG A 1 314 ? 21.390 53.609 32.530 1.00 19.40 ? 314 ARG A CD 1 ATOM 2425 N NE . ARG A 1 314 ? 20.041 53.614 32.027 1.00 20.18 ? 314 ARG A NE 1 ATOM 2426 C CZ . ARG A 1 314 ? 19.522 54.503 31.205 1.00 19.43 ? 314 ARG A CZ 1 ATOM 2427 N NH1 . ARG A 1 314 ? 20.273 55.502 30.734 1.00 22.11 ? 314 ARG A NH1 1 ATOM 2428 N NH2 . ARG A 1 314 ? 18.219 54.487 30.892 1.00 20.60 ? 314 ARG A NH2 1 ATOM 2429 N N . SER A 1 315 ? 21.810 48.140 31.587 1.00 14.35 ? 315 SER A N 1 ATOM 2430 C CA . SER A 1 315 ? 22.292 47.021 30.753 1.00 15.79 ? 315 SER A CA 1 ATOM 2431 C C . SER A 1 315 ? 21.166 46.387 30.003 1.00 17.57 ? 315 SER A C 1 ATOM 2432 O O . SER A 1 315 ? 21.326 45.955 28.838 1.00 18.16 ? 315 SER A O 1 ATOM 2433 C CB . SER A 1 315 ? 22.996 45.972 31.591 1.00 12.69 ? 315 SER A CB 1 ATOM 2434 O OG . SER A 1 315 ? 24.152 46.484 32.202 1.00 15.99 ? 315 SER A OG 1 ATOM 2435 N N A ASP A 1 316 ? 20.007 46.257 30.633 0.50 16.69 ? 316 ASP A N 1 ATOM 2436 N N B ASP A 1 316 ? 20.007 46.257 30.633 0.50 17.96 ? 316 ASP A N 1 ATOM 2437 C CA A ASP A 1 316 ? 18.882 45.679 29.910 0.50 19.11 ? 316 ASP A CA 1 ATOM 2438 C CA B ASP A 1 316 ? 18.882 45.679 29.910 0.50 21.03 ? 316 ASP A CA 1 ATOM 2439 C C A ASP A 1 316 ? 18.543 46.509 28.659 0.50 14.01 ? 316 ASP A C 1 ATOM 2440 C C B ASP A 1 316 ? 18.797 46.239 28.479 0.50 20.11 ? 316 ASP A C 1 ATOM 2441 O O A ASP A 1 316 ? 18.280 45.953 27.574 0.50 11.81 ? 316 ASP A O 1 ATOM 2442 O O B ASP A 1 316 ? 18.558 45.489 27.511 0.50 22.33 ? 316 ASP A O 1 ATOM 2443 C CB A ASP A 1 316 ? 17.664 45.610 30.811 0.50 22.84 ? 316 ASP A CB 1 ATOM 2444 C CB B ASP A 1 316 ? 17.586 45.974 30.641 0.50 21.44 ? 316 ASP A CB 1 ATOM 2445 C CG A ASP A 1 316 ? 16.783 44.443 30.457 0.50 26.82 ? 316 ASP A CG 1 ATOM 2446 C CG B ASP A 1 316 ? 17.412 45.076 31.836 0.50 21.08 ? 316 ASP A CG 1 ATOM 2447 O OD1 A ASP A 1 316 ? 15.542 44.590 30.538 0.50 28.38 ? 316 ASP A OD1 1 ATOM 2448 O OD1 B ASP A 1 316 ? 16.565 45.396 32.700 0.50 20.95 ? 316 ASP A OD1 1 ATOM 2449 O OD2 A ASP A 1 316 ? 17.364 43.385 30.086 0.50 25.14 ? 316 ASP A OD2 1 ATOM 2450 O OD2 B ASP A 1 316 ? 18.134 44.041 31.878 0.50 20.13 ? 316 ASP A OD2 1 ATOM 2451 N N . LEU A 1 317 ? 18.554 47.839 28.782 1.00 16.40 ? 317 LEU A N 1 ATOM 2452 C CA . LEU A 1 317 ? 18.249 48.713 27.634 1.00 15.89 ? 317 LEU A CA 1 ATOM 2453 C C . LEU A 1 317 ? 19.356 48.614 26.565 1.00 13.72 ? 317 LEU A C 1 ATOM 2454 O O . LEU A 1 317 ? 19.031 48.510 25.393 1.00 15.52 ? 317 LEU A O 1 ATOM 2455 C CB . LEU A 1 317 ? 18.133 50.210 28.043 1.00 17.94 ? 317 LEU A CB 1 ATOM 2456 C CG . LEU A 1 317 ? 16.795 50.773 28.533 1.00 23.14 ? 317 LEU A CG 1 ATOM 2457 C CD1 . LEU A 1 317 ? 17.085 52.123 29.228 1.00 26.83 ? 317 LEU A CD1 1 ATOM 2458 C CD2 . LEU A 1 317 ? 15.802 50.950 27.354 1.00 23.24 ? 317 LEU A CD2 1 ATOM 2459 N N . LEU A 1 318 ? 20.603 48.594 26.994 1.00 14.43 ? 318 LEU A N 1 ATOM 2460 C CA . LEU A 1 318 ? 21.707 48.591 26.004 1.00 12.77 ? 318 LEU A CA 1 ATOM 2461 C C . LEU A 1 318 ? 21.813 47.249 25.288 1.00 14.68 ? 318 LEU A C 1 ATOM 2462 O O . LEU A 1 318 ? 21.928 47.213 24.033 1.00 13.81 ? 318 LEU A O 1 ATOM 2463 C CB . LEU A 1 318 ? 22.989 48.956 26.721 1.00 12.58 ? 318 LEU A CB 1 ATOM 2464 C CG . LEU A 1 318 ? 24.228 49.020 25.790 1.00 12.47 ? 318 LEU A CG 1 ATOM 2465 C CD1 . LEU A 1 318 ? 24.046 50.132 24.750 1.00 15.33 ? 318 LEU A CD1 1 ATOM 2466 C CD2 . LEU A 1 318 ? 25.446 49.273 26.657 1.00 15.02 ? 318 LEU A CD2 1 ATOM 2467 N N . VAL A 1 319 ? 21.705 46.143 26.013 1.00 12.42 ? 319 VAL A N 1 ATOM 2468 C CA . VAL A 1 319 ? 21.800 44.819 25.381 1.00 14.04 ? 319 VAL A CA 1 ATOM 2469 C C . VAL A 1 319 ? 20.646 44.641 24.396 1.00 14.61 ? 319 VAL A C 1 ATOM 2470 O O . VAL A 1 319 ? 20.838 44.023 23.341 1.00 13.47 ? 319 VAL A O 1 ATOM 2471 C CB . VAL A 1 319 ? 21.816 43.674 26.435 1.00 13.60 ? 319 VAL A CB 1 ATOM 2472 C CG1 . VAL A 1 319 ? 21.695 42.310 25.739 1.00 13.49 ? 319 VAL A CG1 1 ATOM 2473 C CG2 . VAL A 1 319 ? 23.141 43.735 27.244 1.00 15.71 ? 319 VAL A CG2 1 ATOM 2474 N N . ASP A 1 320 ? 19.461 45.168 24.703 1.00 14.17 ? 320 ASP A N 1 ATOM 2475 C CA . ASP A 1 320 ? 18.320 45.098 23.779 1.00 15.14 ? 320 ASP A CA 1 ATOM 2476 C C . ASP A 1 320 ? 18.663 45.823 22.474 1.00 13.45 ? 320 ASP A C 1 ATOM 2477 O O . ASP A 1 320 ? 18.341 45.313 21.396 1.00 14.05 ? 320 ASP A O 1 ATOM 2478 C CB . ASP A 1 320 ? 17.047 45.672 24.453 1.00 17.26 ? 320 ASP A CB 1 ATOM 2479 C CG . ASP A 1 320 ? 15.869 45.788 23.523 1.00 14.90 ? 320 ASP A CG 1 ATOM 2480 O OD1 . ASP A 1 320 ? 15.421 46.902 23.150 1.00 17.86 ? 320 ASP A OD1 1 ATOM 2481 O OD2 . ASP A 1 320 ? 15.388 44.645 23.167 1.00 20.17 ? 320 ASP A OD2 1 ATOM 2482 N N . GLN A 1 321 ? 19.267 47.024 22.568 1.00 13.37 ? 321 GLN A N 1 ATOM 2483 C CA . GLN A 1 321 ? 19.686 47.733 21.331 1.00 12.26 ? 321 GLN A CA 1 ATOM 2484 C C . GLN A 1 321 ? 20.724 46.882 20.560 1.00 10.71 ? 321 GLN A C 1 ATOM 2485 O O . GLN A 1 321 ? 20.587 46.762 19.349 1.00 11.20 ? 321 GLN A O 1 ATOM 2486 C CB . GLN A 1 321 ? 20.320 49.099 21.686 1.00 11.98 ? 321 GLN A CB 1 ATOM 2487 C CG . GLN A 1 321 ? 19.302 50.162 22.158 1.00 13.58 ? 321 GLN A CG 1 ATOM 2488 C CD . GLN A 1 321 ? 18.246 50.370 21.077 1.00 15.44 ? 321 GLN A CD 1 ATOM 2489 O OE1 . GLN A 1 321 ? 18.583 50.743 19.954 1.00 15.92 ? 321 GLN A OE1 1 ATOM 2490 N NE2 . GLN A 1 321 ? 16.959 50.085 21.384 1.00 14.95 ? 321 GLN A NE2 1 ATOM 2491 N N . TRP A 1 322 ? 21.724 46.323 21.259 1.00 10.99 ? 322 TRP A N 1 ATOM 2492 C CA . TRP A 1 322 ? 22.728 45.513 20.588 1.00 11.60 ? 322 TRP A CA 1 ATOM 2493 C C . TRP A 1 322 ? 22.109 44.314 19.874 1.00 12.42 ? 322 TRP A C 1 ATOM 2494 O O . TRP A 1 322 ? 22.469 43.996 18.725 1.00 11.98 ? 322 TRP A O 1 ATOM 2495 C CB . TRP A 1 322 ? 23.749 45.018 21.599 1.00 11.59 ? 322 TRP A CB 1 ATOM 2496 C CG . TRP A 1 322 ? 24.685 46.065 22.140 1.00 11.99 ? 322 TRP A CG 1 ATOM 2497 C CD1 . TRP A 1 322 ? 24.860 47.355 21.712 1.00 10.94 ? 322 TRP A CD1 1 ATOM 2498 C CD2 . TRP A 1 322 ? 25.591 45.872 23.240 1.00 11.19 ? 322 TRP A CD2 1 ATOM 2499 N NE1 . TRP A 1 322 ? 25.839 47.988 22.496 1.00 12.95 ? 322 TRP A NE1 1 ATOM 2500 C CE2 . TRP A 1 322 ? 26.295 47.093 23.428 1.00 11.60 ? 322 TRP A CE2 1 ATOM 2501 C CE3 . TRP A 1 322 ? 25.885 44.768 24.092 1.00 12.51 ? 322 TRP A CE3 1 ATOM 2502 C CZ2 . TRP A 1 322 ? 27.266 47.263 24.434 1.00 11.92 ? 322 TRP A CZ2 1 ATOM 2503 C CZ3 . TRP A 1 322 ? 26.863 44.950 25.107 1.00 12.52 ? 322 TRP A CZ3 1 ATOM 2504 C CH2 . TRP A 1 322 ? 27.525 46.170 25.270 1.00 12.15 ? 322 TRP A CH2 1 ATOM 2505 N N . LYS A 1 323 ? 21.168 43.640 20.541 1.00 13.14 ? 323 LYS A N 1 ATOM 2506 C CA . LYS A 1 323 ? 20.584 42.435 19.924 1.00 12.05 ? 323 LYS A CA 1 ATOM 2507 C C . LYS A 1 323 ? 19.717 42.796 18.746 1.00 12.70 ? 323 LYS A C 1 ATOM 2508 O O . LYS A 1 323 ? 19.614 42.024 17.779 1.00 13.31 ? 323 LYS A O 1 ATOM 2509 C CB . LYS A 1 323 ? 19.794 41.617 20.969 1.00 13.98 ? 323 LYS A CB 1 ATOM 2510 C CG . LYS A 1 323 ? 20.772 40.825 21.860 1.00 15.30 ? 323 LYS A CG 1 ATOM 2511 C CD . LYS A 1 323 ? 20.083 40.015 22.936 1.00 17.28 ? 323 LYS A CD 1 ATOM 2512 C CE . LYS A 1 323 ? 21.146 39.157 23.626 1.00 14.97 ? 323 LYS A CE 1 ATOM 2513 N NZ . LYS A 1 323 ? 20.411 38.322 24.640 1.00 23.31 ? 323 LYS A NZ 1 ATOM 2514 N N . LYS A 1 324 ? 19.101 43.955 18.763 1.00 11.47 ? 324 LYS A N 1 ATOM 2515 C CA . LYS A 1 324 ? 18.379 44.437 17.572 1.00 11.41 ? 324 LYS A CA 1 ATOM 2516 C C . LYS A 1 324 ? 19.358 44.724 16.428 1.00 11.62 ? 324 LYS A C 1 ATOM 2517 O O . LYS A 1 324 ? 19.101 44.321 15.299 1.00 12.08 ? 324 LYS A O 1 ATOM 2518 C CB . LYS A 1 324 ? 17.575 45.693 17.916 1.00 12.11 ? 324 LYS A CB 1 ATOM 2519 C CG . LYS A 1 324 ? 16.317 45.332 18.728 1.00 12.41 ? 324 LYS A CG 1 ATOM 2520 C CD . LYS A 1 324 ? 15.634 46.578 19.259 1.00 14.29 ? 324 LYS A CD 1 ATOM 2521 C CE . LYS A 1 324 ? 14.402 46.098 20.060 1.00 14.71 ? 324 LYS A CE 1 ATOM 2522 N NZ . LYS A 1 324 ? 13.814 47.232 20.847 1.00 17.34 ? 324 LYS A NZ 1 ATOM 2523 N N . LYS A 1 325 ? 20.444 45.461 16.719 1.00 11.07 ? 325 LYS A N 1 ATOM 2524 C CA . LYS A 1 325 ? 21.456 45.712 15.664 1.00 10.11 ? 325 LYS A CA 1 ATOM 2525 C C . LYS A 1 325 ? 21.968 44.371 15.102 1.00 10.03 ? 325 LYS A C 1 ATOM 2526 O O . LYS A 1 325 ? 22.152 44.210 13.858 1.00 10.12 ? 325 LYS A O 1 ATOM 2527 C CB . LYS A 1 325 ? 22.635 46.498 16.274 1.00 9.49 ? 325 LYS A CB 1 ATOM 2528 C CG . LYS A 1 325 ? 23.495 47.150 15.113 1.00 9.81 ? 325 LYS A CG 1 ATOM 2529 C CD . LYS A 1 325 ? 24.645 47.970 15.752 1.00 12.09 ? 325 LYS A CD 1 ATOM 2530 C CE . LYS A 1 325 ? 25.389 48.754 14.625 1.00 11.32 ? 325 LYS A CE 1 ATOM 2531 N NZ . LYS A 1 325 ? 26.589 49.347 15.254 1.00 12.05 ? 325 LYS A NZ 1 ATOM 2532 N N . ALA A 1 326 ? 22.209 43.377 15.961 1.00 11.07 ? 326 ALA A N 1 ATOM 2533 C CA . ALA A 1 326 ? 22.748 42.094 15.538 1.00 10.43 ? 326 ALA A CA 1 ATOM 2534 C C . ALA A 1 326 ? 21.824 41.358 14.585 1.00 11.13 ? 326 ALA A C 1 ATOM 2535 O O . ALA A 1 326 ? 22.264 40.537 13.787 1.00 12.81 ? 326 ALA A O 1 ATOM 2536 C CB . ALA A 1 326 ? 23.044 41.200 16.765 1.00 11.82 ? 326 ALA A CB 1 ATOM 2537 N N . GLU A 1 327 ? 20.535 41.634 14.661 1.00 12.03 ? 327 GLU A N 1 ATOM 2538 C CA . GLU A 1 327 ? 19.602 40.972 13.732 1.00 13.01 ? 327 GLU A CA 1 ATOM 2539 C C . GLU A 1 327 ? 19.850 41.334 12.266 1.00 13.12 ? 327 GLU A C 1 ATOM 2540 O O . GLU A 1 327 ? 19.382 40.666 11.363 1.00 15.01 ? 327 GLU A O 1 ATOM 2541 C CB . GLU A 1 327 ? 18.199 41.418 14.051 1.00 16.15 ? 327 GLU A CB 1 ATOM 2542 C CG . GLU A 1 327 ? 17.548 40.654 15.143 1.00 22.20 ? 327 GLU A CG 1 ATOM 2543 C CD . GLU A 1 327 ? 17.510 39.139 14.868 1.00 19.42 ? 327 GLU A CD 1 ATOM 2544 O OE1 . GLU A 1 327 ? 16.851 38.654 13.952 1.00 23.31 ? 327 GLU A OE1 1 ATOM 2545 O OE2 . GLU A 1 327 ? 18.190 38.429 15.563 1.00 22.72 ? 327 GLU A OE2 1 ATOM 2546 N N . LEU A 1 328 ? 20.542 42.455 12.019 1.00 11.88 ? 328 LEU A N 1 ATOM 2547 C CA . LEU A 1 328 ? 20.812 42.937 10.659 1.00 10.12 ? 328 LEU A CA 1 ATOM 2548 C C . LEU A 1 328 ? 22.041 42.274 10.060 1.00 11.57 ? 328 LEU A C 1 ATOM 2549 O O . LEU A 1 328 ? 22.303 42.523 8.866 1.00 13.26 ? 328 LEU A O 1 ATOM 2550 C CB . LEU A 1 328 ? 21.006 44.450 10.720 1.00 10.69 ? 328 LEU A CB 1 ATOM 2551 C CG . LEU A 1 328 ? 19.884 45.230 11.388 1.00 10.05 ? 328 LEU A CG 1 ATOM 2552 C CD1 . LEU A 1 328 ? 20.100 46.712 11.196 1.00 13.48 ? 328 LEU A CD1 1 ATOM 2553 C CD2 . LEU A 1 328 ? 18.484 44.842 10.850 1.00 13.75 ? 328 LEU A CD2 1 ATOM 2554 N N . TYR A 1 329 ? 22.753 41.430 10.797 1.00 10.17 ? 329 TYR A N 1 ATOM 2555 C CA . TYR A 1 329 ? 23.979 40.816 10.313 1.00 10.34 ? 329 TYR A CA 1 ATOM 2556 C C . TYR A 1 329 ? 23.957 39.313 10.499 1.00 11.93 ? 329 TYR A C 1 ATOM 2557 O O . TYR A 1 329 ? 23.068 38.796 11.227 1.00 13.60 ? 329 TYR A O 1 ATOM 2558 C CB . TYR A 1 329 ? 25.214 41.427 11.021 1.00 10.41 ? 329 TYR A CB 1 ATOM 2559 C CG . TYR A 1 329 ? 25.419 42.910 10.691 1.00 10.12 ? 329 TYR A CG 1 ATOM 2560 C CD1 . TYR A 1 329 ? 24.839 43.907 11.474 1.00 11.01 ? 329 TYR A CD1 1 ATOM 2561 C CD2 . TYR A 1 329 ? 26.150 43.289 9.577 1.00 10.69 ? 329 TYR A CD2 1 ATOM 2562 C CE1 . TYR A 1 329 ? 24.958 45.276 11.152 1.00 11.87 ? 329 TYR A CE1 1 ATOM 2563 C CE2 . TYR A 1 329 ? 26.296 44.650 9.223 1.00 11.73 ? 329 TYR A CE2 1 ATOM 2564 C CZ . TYR A 1 329 ? 25.694 45.611 10.002 1.00 10.56 ? 329 TYR A CZ 1 ATOM 2565 O OH . TYR A 1 329 ? 25.753 46.953 9.664 1.00 12.42 ? 329 TYR A OH 1 ATOM 2566 N N . ARG A 1 330 ? 24.873 38.610 9.883 1.00 11.62 ? 330 ARG A N 1 ATOM 2567 C CA . ARG A 1 330 ? 24.867 37.147 9.862 1.00 11.33 ? 330 ARG A CA 1 ATOM 2568 C C . ARG A 1 330 ? 25.663 36.377 10.894 1.00 12.85 ? 330 ARG A C 1 ATOM 2569 O O . ARG A 1 330 ? 25.441 35.166 11.032 1.00 15.34 ? 330 ARG A O 1 ATOM 2570 C CB . ARG A 1 330 ? 25.276 36.642 8.447 1.00 12.53 ? 330 ARG A CB 1 ATOM 2571 C CG . ARG A 1 330 ? 24.344 37.131 7.329 1.00 12.70 ? 330 ARG A CG 1 ATOM 2572 C CD . ARG A 1 330 ? 24.726 36.550 5.951 1.00 12.20 ? 330 ARG A CD 1 ATOM 2573 N NE . ARG A 1 330 ? 23.769 37.108 4.999 1.00 14.36 ? 330 ARG A NE 1 ATOM 2574 C CZ . ARG A 1 330 ? 23.466 36.587 3.816 1.00 15.54 ? 330 ARG A CZ 1 ATOM 2575 N NH1 . ARG A 1 330 ? 24.055 35.474 3.395 1.00 17.28 ? 330 ARG A NH1 1 ATOM 2576 N NH2 . ARG A 1 330 ? 22.583 37.241 3.051 1.00 15.30 ? 330 ARG A NH2 1 ATOM 2577 N N . THR A 1 331 ? 26.627 37.002 11.544 1.00 12.52 ? 331 THR A N 1 ATOM 2578 C CA . THR A 1 331 ? 27.401 36.266 12.554 1.00 11.60 ? 331 THR A CA 1 ATOM 2579 C C . THR A 1 331 ? 27.000 36.669 13.968 1.00 12.17 ? 331 THR A C 1 ATOM 2580 O O . THR A 1 331 ? 26.179 37.550 14.176 1.00 14.25 ? 331 THR A O 1 ATOM 2581 C CB . THR A 1 331 ? 28.948 36.494 12.409 1.00 12.63 ? 331 THR A CB 1 ATOM 2582 O OG1 . THR A 1 331 ? 29.308 37.802 12.912 1.00 12.21 ? 331 THR A OG1 1 ATOM 2583 C CG2 . THR A 1 331 ? 29.394 36.343 10.917 1.00 13.35 ? 331 THR A CG2 1 ATOM 2584 N N . ASN A 1 332 ? 27.621 36.012 14.944 1.00 12.14 ? 332 ASN A N 1 ATOM 2585 C CA . ASN A 1 332 ? 27.387 36.364 16.348 1.00 12.73 ? 332 ASN A CA 1 ATOM 2586 C C . ASN A 1 332 ? 28.468 37.302 16.861 1.00 11.88 ? 332 ASN A C 1 ATOM 2587 O O . ASN A 1 332 ? 28.716 37.340 18.079 1.00 13.22 ? 332 ASN A O 1 ATOM 2588 C CB . ASN A 1 332 ? 27.325 35.097 17.252 1.00 13.89 ? 332 ASN A CB 1 ATOM 2589 C CG . ASN A 1 332 ? 28.674 34.381 17.354 1.00 17.44 ? 332 ASN A CG 1 ATOM 2590 O OD1 . ASN A 1 332 ? 29.463 34.392 16.438 1.00 16.78 ? 332 ASN A OD1 1 ATOM 2591 N ND2 . ASN A 1 332 ? 28.944 33.723 18.499 1.00 20.07 ? 332 ASN A ND2 1 ATOM 2592 N N . VAL A 1 333 ? 29.079 38.085 15.952 1.00 10.51 ? 333 VAL A N 1 ATOM 2593 C CA . VAL A 1 333 ? 30.112 39.066 16.352 1.00 10.42 ? 333 VAL A CA 1 ATOM 2594 C C . VAL A 1 333 ? 29.565 40.426 15.933 1.00 10.16 ? 333 VAL A C 1 ATOM 2595 O O . VAL A 1 333 ? 29.290 40.628 14.731 1.00 11.33 ? 333 VAL A O 1 ATOM 2596 C CB . VAL A 1 333 ? 31.428 38.790 15.601 1.00 11.45 ? 333 VAL A CB 1 ATOM 2597 C CG1 . VAL A 1 333 ? 32.482 39.818 16.018 1.00 13.28 ? 333 VAL A CG1 1 ATOM 2598 C CG2 . VAL A 1 333 ? 31.904 37.383 15.878 1.00 15.86 ? 333 VAL A CG2 1 ATOM 2599 N N . LEU A 1 334 ? 29.438 41.382 16.843 1.00 10.18 ? 334 LEU A N 1 ATOM 2600 C CA . LEU A 1 334 ? 28.823 42.661 16.602 1.00 9.13 ? 334 LEU A CA 1 ATOM 2601 C C . LEU A 1 334 ? 29.792 43.821 16.784 1.00 9.52 ? 334 LEU A C 1 ATOM 2602 O O . LEU A 1 334 ? 30.511 43.921 17.784 1.00 11.17 ? 334 LEU A O 1 ATOM 2603 C CB . LEU A 1 334 ? 27.625 42.827 17.589 1.00 10.22 ? 334 LEU A CB 1 ATOM 2604 C CG . LEU A 1 334 ? 26.809 44.136 17.402 1.00 9.79 ? 334 LEU A CG 1 ATOM 2605 C CD1 . LEU A 1 334 ? 25.955 44.042 16.097 1.00 11.67 ? 334 LEU A CD1 1 ATOM 2606 C CD2 . LEU A 1 334 ? 25.853 44.289 18.619 1.00 12.63 ? 334 LEU A CD2 1 ATOM 2607 N N . LEU A 1 335 ? 29.773 44.736 15.803 1.00 9.63 ? 335 LEU A N 1 ATOM 2608 C CA . LEU A 1 335 ? 30.611 45.941 15.848 1.00 9.56 ? 335 LEU A CA 1 ATOM 2609 C C . LEU A 1 335 ? 29.815 47.108 16.395 1.00 7.37 ? 335 LEU A C 1 ATOM 2610 O O . LEU A 1 335 ? 28.750 47.439 15.861 1.00 10.08 ? 335 LEU A O 1 ATOM 2611 C CB . LEU A 1 335 ? 31.089 46.289 14.405 1.00 9.10 ? 335 LEU A CB 1 ATOM 2612 C CG . LEU A 1 335 ? 31.934 47.582 14.299 1.00 9.34 ? 335 LEU A CG 1 ATOM 2613 C CD1 . LEU A 1 335 ? 33.248 47.399 15.042 1.00 11.43 ? 335 LEU A CD1 1 ATOM 2614 C CD2 . LEU A 1 335 ? 32.154 47.917 12.846 1.00 12.41 ? 335 LEU A CD2 1 ATOM 2615 N N . ILE A 1 336 ? 30.327 47.748 17.456 1.00 8.64 ? 336 ILE A N 1 ATOM 2616 C CA . ILE A 1 336 ? 29.704 48.932 18.053 1.00 8.98 ? 336 ILE A CA 1 ATOM 2617 C C . ILE A 1 336 ? 30.724 50.065 18.103 1.00 8.15 ? 336 ILE A C 1 ATOM 2618 O O . ILE A 1 336 ? 31.546 50.157 19.014 1.00 9.75 ? 336 ILE A O 1 ATOM 2619 C CB . ILE A 1 336 ? 29.183 48.645 19.501 1.00 9.61 ? 336 ILE A CB 1 ATOM 2620 C CG1 . ILE A 1 336 ? 28.125 47.511 19.514 1.00 9.77 ? 336 ILE A CG1 1 ATOM 2621 C CG2 . ILE A 1 336 ? 28.592 49.959 20.082 1.00 11.00 ? 336 ILE A CG2 1 ATOM 2622 C CD1 . ILE A 1 336 ? 26.825 47.789 18.790 1.00 11.49 ? 336 ILE A CD1 1 ATOM 2623 N N . PRO A 1 337 ? 30.740 50.922 17.070 1.00 9.70 ? 337 PRO A N 1 ATOM 2624 C CA . PRO A 1 337 ? 31.665 52.076 17.116 1.00 9.66 ? 337 PRO A CA 1 ATOM 2625 C C . PRO A 1 337 ? 31.276 52.977 18.296 1.00 9.82 ? 337 PRO A C 1 ATOM 2626 O O . PRO A 1 337 ? 30.068 53.109 18.575 1.00 10.60 ? 337 PRO A O 1 ATOM 2627 C CB . PRO A 1 337 ? 31.394 52.799 15.768 1.00 9.28 ? 337 PRO A CB 1 ATOM 2628 C CG . PRO A 1 337 ? 30.948 51.653 14.850 1.00 9.41 ? 337 PRO A CG 1 ATOM 2629 C CD . PRO A 1 337 ? 29.988 50.879 15.805 1.00 10.43 ? 337 PRO A CD 1 ATOM 2630 N N . LEU A 1 338 ? 32.252 53.638 18.921 1.00 8.93 ? 338 LEU A N 1 ATOM 2631 C CA . LEU A 1 338 ? 31.978 54.556 20.039 1.00 8.17 ? 338 LEU A CA 1 ATOM 2632 C C . LEU A 1 338 ? 32.806 55.831 19.808 1.00 9.31 ? 338 LEU A C 1 ATOM 2633 O O . LEU A 1 338 ? 33.968 55.908 20.211 1.00 9.08 ? 338 LEU A O 1 ATOM 2634 C CB . LEU A 1 338 ? 32.340 53.875 21.375 1.00 9.47 ? 338 LEU A CB 1 ATOM 2635 C CG . LEU A 1 338 ? 31.973 54.778 22.564 1.00 9.66 ? 338 LEU A CG 1 ATOM 2636 C CD1 . LEU A 1 338 ? 30.434 54.671 22.859 1.00 11.93 ? 338 LEU A CD1 1 ATOM 2637 C CD2 . LEU A 1 338 ? 32.731 54.303 23.823 1.00 13.80 ? 338 LEU A CD2 1 ATOM 2638 N N . GLY A 1 339 ? 32.197 56.818 19.158 1.00 9.07 ? 339 GLY A N 1 ATOM 2639 C CA . GLY A 1 339 ? 32.962 58.022 18.837 1.00 9.34 ? 339 GLY A CA 1 ATOM 2640 C C . GLY A 1 339 ? 32.124 59.004 18.052 1.00 10.75 ? 339 GLY A C 1 ATOM 2641 O O . GLY A 1 339 ? 30.941 58.741 17.751 1.00 10.55 ? 339 GLY A O 1 ATOM 2642 N N . ASP A 1 340 ? 32.757 60.146 17.691 1.00 9.51 ? 340 ASP A N 1 ATOM 2643 C CA . ASP A 1 340 ? 32.118 61.224 16.934 1.00 9.07 ? 340 ASP A CA 1 ATOM 2644 C C . ASP A 1 340 ? 33.273 62.176 16.544 1.00 8.74 ? 340 ASP A C 1 ATOM 2645 O O . ASP A 1 340 ? 34.452 61.886 16.748 1.00 9.84 ? 340 ASP A O 1 ATOM 2646 C CB . ASP A 1 340 ? 31.039 61.874 17.845 1.00 9.69 ? 340 ASP A CB 1 ATOM 2647 C CG . ASP A 1 340 ? 29.918 62.645 17.113 1.00 12.55 ? 340 ASP A CG 1 ATOM 2648 O OD1 . ASP A 1 340 ? 30.112 62.978 15.907 1.00 13.11 ? 340 ASP A OD1 1 ATOM 2649 O OD2 . ASP A 1 340 ? 28.863 62.901 17.786 1.00 14.30 ? 340 ASP A OD2 1 ATOM 2650 N N . ASN A 1 341 ? 32.855 63.340 16.054 1.00 9.80 ? 341 ASN A N 1 ATOM 2651 C CA . ASN A 1 341 ? 33.821 64.329 15.490 1.00 9.17 ? 341 ASN A CA 1 ATOM 2652 C C . ASN A 1 341 ? 34.696 64.885 16.606 1.00 8.38 ? 341 ASN A C 1 ATOM 2653 O O . ASN A 1 341 ? 34.210 65.352 17.638 1.00 10.13 ? 341 ASN A O 1 ATOM 2654 C CB . ASN A 1 341 ? 33.066 65.483 14.811 1.00 11.55 ? 341 ASN A CB 1 ATOM 2655 C CG . ASN A 1 341 ? 32.310 65.034 13.591 1.00 11.96 ? 341 ASN A CG 1 ATOM 2656 O OD1 . ASN A 1 341 ? 32.539 63.925 13.052 1.00 13.03 ? 341 ASN A OD1 1 ATOM 2657 N ND2 . ASN A 1 341 ? 31.432 65.928 13.092 1.00 17.51 ? 341 ASN A ND2 1 ATOM 2658 N N . PHE A 1 342 ? 36.008 64.805 16.408 1.00 8.92 ? 342 PHE A N 1 ATOM 2659 C CA . PHE A 1 342 ? 36.968 65.331 17.352 1.00 9.79 ? 342 PHE A CA 1 ATOM 2660 C C . PHE A 1 342 ? 36.689 64.931 18.796 1.00 9.13 ? 342 PHE A C 1 ATOM 2661 O O . PHE A 1 342 ? 36.947 65.724 19.744 1.00 11.76 ? 342 PHE A O 1 ATOM 2662 C CB . PHE A 1 342 ? 37.125 66.876 17.186 1.00 9.09 ? 342 PHE A CB 1 ATOM 2663 C CG . PHE A 1 342 ? 37.692 67.270 15.857 1.00 10.42 ? 342 PHE A CG 1 ATOM 2664 C CD1 . PHE A 1 342 ? 36.865 67.742 14.818 1.00 10.20 ? 342 PHE A CD1 1 ATOM 2665 C CD2 . PHE A 1 342 ? 39.087 67.186 15.625 1.00 10.02 ? 342 PHE A CD2 1 ATOM 2666 C CE1 . PHE A 1 342 ? 37.422 68.144 13.553 1.00 11.73 ? 342 PHE A CE1 1 ATOM 2667 C CE2 . PHE A 1 342 ? 39.624 67.583 14.395 1.00 10.31 ? 342 PHE A CE2 1 ATOM 2668 C CZ . PHE A 1 342 ? 38.778 68.068 13.369 1.00 11.03 ? 342 PHE A CZ 1 ATOM 2669 N N . ARG A 1 343 ? 36.290 63.662 18.977 1.00 8.76 ? 343 ARG A N 1 ATOM 2670 C CA . ARG A 1 343 ? 36.090 63.161 20.340 1.00 9.20 ? 343 ARG A CA 1 ATOM 2671 C C . ARG A 1 343 ? 37.396 62.695 20.983 1.00 11.71 ? 343 ARG A C 1 ATOM 2672 O O . ARG A 1 343 ? 38.462 62.628 20.364 1.00 10.24 ? 343 ARG A O 1 ATOM 2673 C CB . ARG A 1 343 ? 35.069 62.006 20.324 1.00 9.79 ? 343 ARG A CB 1 ATOM 2674 C CG . ARG A 1 343 ? 33.626 62.433 20.110 1.00 10.46 ? 343 ARG A CG 1 ATOM 2675 C CD . ARG A 1 343 ? 33.146 63.394 21.239 1.00 10.38 ? 343 ARG A CD 1 ATOM 2676 N NE . ARG A 1 343 ? 31.690 63.650 21.148 1.00 10.16 ? 343 ARG A NE 1 ATOM 2677 C CZ . ARG A 1 343 ? 30.777 62.911 21.791 1.00 10.88 ? 343 ARG A CZ 1 ATOM 2678 N NH1 . ARG A 1 343 ? 31.159 61.861 22.529 1.00 10.26 ? 343 ARG A NH1 1 ATOM 2679 N NH2 . ARG A 1 343 ? 29.501 63.294 21.695 1.00 11.20 ? 343 ARG A NH2 1 ATOM 2680 N N . PHE A 1 344 ? 37.281 62.384 22.266 1.00 11.47 ? 344 PHE A N 1 ATOM 2681 C CA . PHE A 1 344 ? 38.415 61.917 23.100 1.00 11.03 ? 344 PHE A CA 1 ATOM 2682 C C . PHE A 1 344 ? 39.485 62.956 23.236 1.00 12.24 ? 344 PHE A C 1 ATOM 2683 O O . PHE A 1 344 ? 40.696 62.669 23.206 1.00 15.46 ? 344 PHE A O 1 ATOM 2684 C CB . PHE A 1 344 ? 38.873 60.544 22.587 1.00 11.89 ? 344 PHE A CB 1 ATOM 2685 C CG . PHE A 1 344 ? 37.843 59.483 22.799 1.00 12.42 ? 344 PHE A CG 1 ATOM 2686 C CD1 . PHE A 1 344 ? 37.033 59.042 21.769 1.00 12.45 ? 344 PHE A CD1 1 ATOM 2687 C CD2 . PHE A 1 344 ? 37.639 58.946 24.090 1.00 15.97 ? 344 PHE A CD2 1 ATOM 2688 C CE1 . PHE A 1 344 ? 36.045 58.100 21.978 1.00 13.54 ? 344 PHE A CE1 1 ATOM 2689 C CE2 . PHE A 1 344 ? 36.648 57.991 24.298 1.00 15.07 ? 344 PHE A CE2 1 ATOM 2690 C CZ . PHE A 1 344 ? 35.865 57.579 23.253 1.00 12.73 ? 344 PHE A CZ 1 ATOM 2691 N N . LYS A 1 345 ? 39.067 64.193 23.434 1.00 12.41 ? 345 LYS A N 1 ATOM 2692 C CA . LYS A 1 345 ? 39.945 65.313 23.592 1.00 14.08 ? 345 LYS A CA 1 ATOM 2693 C C . LYS A 1 345 ? 40.414 65.610 25.025 1.00 17.22 ? 345 LYS A C 1 ATOM 2694 O O . LYS A 1 345 ? 41.588 65.981 25.199 1.00 23.04 ? 345 LYS A O 1 ATOM 2695 C CB . LYS A 1 345 ? 39.239 66.552 23.076 1.00 17.28 ? 345 LYS A CB 1 ATOM 2696 C CG . LYS A 1 345 ? 40.055 67.743 23.187 1.00 16.19 ? 345 LYS A CG 1 ATOM 2697 C CD . LYS A 1 345 ? 39.353 68.908 22.500 1.00 22.85 ? 345 LYS A CD 1 ATOM 2698 C CE . LYS A 1 345 ? 40.056 70.204 22.764 1.00 22.91 ? 345 LYS A CE 1 ATOM 2699 N NZ . LYS A 1 345 ? 39.249 71.307 22.111 1.00 26.74 ? 345 LYS A NZ 1 ATOM 2700 N N . GLN A 1 346 ? 39.446 65.646 25.930 1.00 15.26 ? 346 GLN A N 1 ATOM 2701 C CA . GLN A 1 346 ? 39.681 65.966 27.353 1.00 16.79 ? 346 GLN A CA 1 ATOM 2702 C C . GLN A 1 346 ? 39.958 64.672 28.145 1.00 15.90 ? 346 GLN A C 1 ATOM 2703 O O . GLN A 1 346 ? 39.317 63.607 27.898 1.00 13.03 ? 346 GLN A O 1 ATOM 2704 C CB . GLN A 1 346 ? 38.416 66.646 27.975 1.00 18.60 ? 346 GLN A CB 1 ATOM 2705 C CG . GLN A 1 346 ? 37.913 68.030 27.381 1.00 25.30 ? 346 GLN A CG 1 ATOM 2706 C CD . GLN A 1 346 ? 36.696 67.874 26.428 1.00 25.42 ? 346 GLN A CD 1 ATOM 2707 O OE1 . GLN A 1 346 ? 36.649 66.925 25.614 1.00 21.58 ? 346 GLN A OE1 1 ATOM 2708 N NE2 . GLN A 1 346 ? 35.722 68.781 26.519 1.00 25.60 ? 346 GLN A NE2 1 ATOM 2709 N N . ASN A 1 347 ? 40.873 64.726 29.113 1.00 16.34 ? 347 ASN A N 1 ATOM 2710 C CA . ASN A 1 347 ? 41.122 63.566 29.986 1.00 15.43 ? 347 ASN A CA 1 ATOM 2711 C C . ASN A 1 347 ? 39.832 63.141 30.697 1.00 13.54 ? 347 ASN A C 1 ATOM 2712 O O . ASN A 1 347 ? 39.565 61.939 30.792 1.00 14.75 ? 347 ASN A O 1 ATOM 2713 C CB . ASN A 1 347 ? 42.150 63.927 31.088 1.00 18.87 ? 347 ASN A CB 1 ATOM 2714 C CG . ASN A 1 347 ? 43.446 64.144 30.500 1.00 27.56 ? 347 ASN A CG 1 ATOM 2715 O OD1 . ASN A 1 347 ? 43.918 63.263 29.807 1.00 27.10 ? 347 ASN A OD1 1 ATOM 2716 N ND2 . ASN A 1 347 ? 44.053 65.333 30.702 1.00 31.68 ? 347 ASN A ND2 1 ATOM 2717 N N . THR A 1 348 ? 39.008 64.097 31.123 1.00 12.81 ? 348 THR A N 1 ATOM 2718 C CA . THR A 1 348 ? 37.758 63.785 31.785 1.00 13.65 ? 348 THR A CA 1 ATOM 2719 C C . THR A 1 348 ? 36.808 63.027 30.842 1.00 14.39 ? 348 THR A C 1 ATOM 2720 O O . THR A 1 348 ? 35.947 62.265 31.309 1.00 14.47 ? 348 THR A O 1 ATOM 2721 C CB . THR A 1 348 ? 37.068 65.075 32.293 1.00 16.04 ? 348 THR A CB 1 ATOM 2722 O OG1 . THR A 1 348 ? 36.947 66.003 31.201 1.00 19.96 ? 348 THR A OG1 1 ATOM 2723 C CG2 . THR A 1 348 ? 37.878 65.708 33.490 1.00 17.37 ? 348 THR A CG2 1 ATOM 2724 N N . GLU A 1 349 ? 36.886 63.273 29.525 1.00 10.73 ? 349 GLU A N 1 ATOM 2725 C CA . GLU A 1 349 ? 36.046 62.536 28.557 1.00 12.24 ? 349 GLU A CA 1 ATOM 2726 C C . GLU A 1 349 ? 36.491 61.086 28.434 1.00 11.00 ? 349 GLU A C 1 ATOM 2727 O O . GLU A 1 349 ? 35.660 60.166 28.417 1.00 10.73 ? 349 GLU A O 1 ATOM 2728 C CB . GLU A 1 349 ? 36.091 63.222 27.176 1.00 12.04 ? 349 GLU A CB 1 ATOM 2729 C CG . GLU A 1 349 ? 35.315 62.471 26.142 1.00 12.31 ? 349 GLU A CG 1 ATOM 2730 C CD . GLU A 1 349 ? 35.537 63.061 24.733 1.00 13.58 ? 349 GLU A CD 1 ATOM 2731 O OE1 . GLU A 1 349 ? 35.026 62.440 23.809 1.00 14.03 ? 349 GLU A OE1 1 ATOM 2732 O OE2 . GLU A 1 349 ? 36.220 64.099 24.595 1.00 15.36 ? 349 GLU A OE2 1 ATOM 2733 N N . TRP A 1 350 ? 37.795 60.863 28.349 1.00 10.85 ? 350 TRP A N 1 ATOM 2734 C CA . TRP A 1 350 ? 38.316 59.486 28.329 1.00 10.56 ? 350 TRP A CA 1 ATOM 2735 C C . TRP A 1 350 ? 37.795 58.733 29.563 1.00 11.15 ? 350 TRP A C 1 ATOM 2736 O O . TRP A 1 350 ? 37.287 57.610 29.471 1.00 11.96 ? 350 TRP A O 1 ATOM 2737 C CB . TRP A 1 350 ? 39.857 59.442 28.377 1.00 10.00 ? 350 TRP A CB 1 ATOM 2738 C CG . TRP A 1 350 ? 40.477 59.724 27.043 1.00 10.42 ? 350 TRP A CG 1 ATOM 2739 C CD1 . TRP A 1 350 ? 40.788 60.926 26.514 1.00 10.56 ? 350 TRP A CD1 1 ATOM 2740 C CD2 . TRP A 1 350 ? 40.787 58.742 26.059 1.00 10.58 ? 350 TRP A CD2 1 ATOM 2741 N NE1 . TRP A 1 350 ? 41.296 60.770 25.244 1.00 10.37 ? 350 TRP A NE1 1 ATOM 2742 C CE2 . TRP A 1 350 ? 41.284 59.441 24.925 1.00 10.77 ? 350 TRP A CE2 1 ATOM 2743 C CE3 . TRP A 1 350 ? 40.690 57.358 26.010 1.00 14.05 ? 350 TRP A CE3 1 ATOM 2744 C CZ2 . TRP A 1 350 ? 41.680 58.772 23.740 1.00 12.72 ? 350 TRP A CZ2 1 ATOM 2745 C CZ3 . TRP A 1 350 ? 41.085 56.706 24.821 1.00 16.77 ? 350 TRP A CZ3 1 ATOM 2746 C CH2 . TRP A 1 350 ? 41.561 57.424 23.721 1.00 14.21 ? 350 TRP A CH2 1 ATOM 2747 N N . ASP A 1 351 ? 37.855 59.374 30.743 1.00 11.91 ? 351 ASP A N 1 ATOM 2748 C CA . ASP A 1 351 ? 37.420 58.713 31.971 1.00 13.00 ? 351 ASP A CA 1 ATOM 2749 C C . ASP A 1 351 ? 35.921 58.463 31.962 1.00 11.39 ? 351 ASP A C 1 ATOM 2750 O O . ASP A 1 351 ? 35.480 57.331 32.304 1.00 13.22 ? 351 ASP A O 1 ATOM 2751 C CB . ASP A 1 351 ? 37.735 59.592 33.197 1.00 15.62 ? 351 ASP A CB 1 ATOM 2752 C CG . ASP A 1 351 ? 39.198 59.670 33.518 1.00 20.71 ? 351 ASP A CG 1 ATOM 2753 O OD1 . ASP A 1 351 ? 39.953 58.716 33.233 1.00 25.44 ? 351 ASP A OD1 1 ATOM 2754 O OD2 . ASP A 1 351 ? 39.579 60.681 34.141 1.00 28.85 ? 351 ASP A OD2 1 ATOM 2755 N N . VAL A 1 352 ? 35.122 59.445 31.582 1.00 12.25 ? 352 VAL A N 1 ATOM 2756 C CA . VAL A 1 352 ? 33.690 59.238 31.666 1.00 12.52 ? 352 VAL A CA 1 ATOM 2757 C C . VAL A 1 352 ? 33.245 58.140 30.700 1.00 13.67 ? 352 VAL A C 1 ATOM 2758 O O . VAL A 1 352 ? 32.370 57.328 31.041 1.00 14.23 ? 352 VAL A O 1 ATOM 2759 C CB . VAL A 1 352 ? 32.927 60.599 31.503 1.00 16.43 ? 352 VAL A CB 1 ATOM 2760 C CG1 . VAL A 1 352 ? 32.684 60.965 30.066 1.00 15.11 ? 352 VAL A CG1 1 ATOM 2761 C CG2 . VAL A 1 352 ? 31.662 60.586 32.332 1.00 21.29 ? 352 VAL A CG2 1 ATOM 2762 N N . GLN A 1 353 ? 33.814 58.032 29.493 1.00 11.29 ? 353 GLN A N 1 ATOM 2763 C CA . GLN A 1 353 ? 33.378 56.960 28.628 1.00 10.00 ? 353 GLN A CA 1 ATOM 2764 C C . GLN A 1 353 ? 33.925 55.617 29.087 1.00 11.26 ? 353 GLN A C 1 ATOM 2765 O O . GLN A 1 353 ? 33.165 54.620 29.197 1.00 13.00 ? 353 GLN A O 1 ATOM 2766 C CB . GLN A 1 353 ? 33.818 57.202 27.158 1.00 11.14 ? 353 GLN A CB 1 ATOM 2767 C CG . GLN A 1 353 ? 33.299 58.490 26.512 1.00 11.63 ? 353 GLN A CG 1 ATOM 2768 C CD . GLN A 1 353 ? 31.849 58.453 26.070 1.00 11.70 ? 353 GLN A CD 1 ATOM 2769 O OE1 . GLN A 1 353 ? 30.996 57.766 26.677 1.00 12.56 ? 353 GLN A OE1 1 ATOM 2770 N NE2 . GLN A 1 353 ? 31.518 59.207 25.053 1.00 11.34 ? 353 GLN A NE2 1 ATOM 2771 N N . ARG A 1 354 ? 35.199 55.549 29.412 1.00 10.34 ? 354 ARG A N 1 ATOM 2772 C CA . ARG A 1 354 ? 35.765 54.295 29.804 1.00 11.28 ? 354 ARG A CA 1 ATOM 2773 C C . ARG A 1 354 ? 35.162 53.703 31.091 1.00 12.13 ? 354 ARG A C 1 ATOM 2774 O O . ARG A 1 354 ? 34.824 52.488 31.111 1.00 12.85 ? 354 ARG A O 1 ATOM 2775 C CB . ARG A 1 354 ? 37.283 54.416 30.023 1.00 11.07 ? 354 ARG A CB 1 ATOM 2776 C CG . ARG A 1 354 ? 37.938 53.062 30.497 1.00 11.64 ? 354 ARG A CG 1 ATOM 2777 C CD . ARG A 1 354 ? 39.476 53.219 30.751 1.00 14.52 ? 354 ARG A CD 1 ATOM 2778 N NE . ARG A 1 354 ? 39.782 54.280 31.725 1.00 16.22 ? 354 ARG A NE 1 ATOM 2779 C CZ . ARG A 1 354 ? 39.656 54.182 33.063 1.00 16.91 ? 354 ARG A CZ 1 ATOM 2780 N NH1 . ARG A 1 354 ? 39.226 53.061 33.613 1.00 17.61 ? 354 ARG A NH1 1 ATOM 2781 N NH2 . ARG A 1 354 ? 39.973 55.198 33.820 1.00 18.65 ? 354 ARG A NH2 1 ATOM 2782 N N . VAL A 1 355 ? 35.028 54.505 32.143 1.00 12.04 ? 355 VAL A N 1 ATOM 2783 C CA . VAL A 1 355 ? 34.576 53.913 33.410 1.00 12.45 ? 355 VAL A CA 1 ATOM 2784 C C . VAL A 1 355 ? 33.128 53.475 33.303 1.00 12.82 ? 355 VAL A C 1 ATOM 2785 O O . VAL A 1 355 ? 32.773 52.402 33.877 1.00 13.76 ? 355 VAL A O 1 ATOM 2786 C CB . VAL A 1 355 ? 34.743 54.963 34.559 1.00 14.41 ? 355 VAL A CB 1 ATOM 2787 C CG1 . VAL A 1 355 ? 34.050 54.531 35.866 1.00 21.10 ? 355 VAL A CG1 1 ATOM 2788 C CG2 . VAL A 1 355 ? 36.229 55.218 34.815 1.00 16.08 ? 355 VAL A CG2 1 ATOM 2789 N N . ASN A 1 356 ? 32.252 54.247 32.669 1.00 11.47 ? 356 ASN A N 1 ATOM 2790 C CA . ASN A 1 356 ? 30.864 53.830 32.554 1.00 11.65 ? 356 ASN A CA 1 ATOM 2791 C C . ASN A 1 356 ? 30.724 52.565 31.709 1.00 12.98 ? 356 ASN A C 1 ATOM 2792 O O . ASN A 1 356 ? 29.973 51.634 32.081 1.00 12.61 ? 356 ASN A O 1 ATOM 2793 C CB . ASN A 1 356 ? 30.018 54.985 32.052 1.00 12.26 ? 356 ASN A CB 1 ATOM 2794 C CG . ASN A 1 356 ? 29.796 56.014 33.127 1.00 13.81 ? 356 ASN A CG 1 ATOM 2795 O OD1 . ASN A 1 356 ? 29.093 55.686 34.116 1.00 14.17 ? 356 ASN A OD1 1 ATOM 2796 N ND2 . ASN A 1 356 ? 30.412 57.191 33.066 1.00 13.29 ? 356 ASN A ND2 1 ATOM 2797 N N . TYR A 1 357 ? 31.460 52.457 30.590 1.00 11.19 ? 357 TYR A N 1 ATOM 2798 C CA . TYR A 1 357 ? 31.389 51.242 29.790 1.00 12.78 ? 357 TYR A CA 1 ATOM 2799 C C . TYR A 1 357 ? 31.998 50.090 30.556 1.00 11.69 ? 357 TYR A C 1 ATOM 2800 O O . TYR A 1 357 ? 31.459 48.965 30.472 1.00 12.40 ? 357 TYR A O 1 ATOM 2801 C CB . TYR A 1 357 ? 32.041 51.466 28.370 1.00 11.46 ? 357 TYR A CB 1 ATOM 2802 C CG . TYR A 1 357 ? 31.022 51.981 27.407 1.00 10.93 ? 357 TYR A CG 1 ATOM 2803 C CD1 . TYR A 1 357 ? 30.840 53.354 27.238 1.00 10.71 ? 357 TYR A CD1 1 ATOM 2804 C CD2 . TYR A 1 357 ? 30.198 51.082 26.687 1.00 11.21 ? 357 TYR A CD2 1 ATOM 2805 C CE1 . TYR A 1 357 ? 29.881 53.833 26.384 1.00 10.41 ? 357 TYR A CE1 1 ATOM 2806 C CE2 . TYR A 1 357 ? 29.220 51.551 25.853 1.00 11.11 ? 357 TYR A CE2 1 ATOM 2807 C CZ . TYR A 1 357 ? 29.057 52.936 25.701 1.00 11.17 ? 357 TYR A CZ 1 ATOM 2808 O OH . TYR A 1 357 ? 28.062 53.344 24.878 1.00 12.55 ? 357 TYR A OH 1 ATOM 2809 N N . GLU A 1 358 ? 33.091 50.292 31.296 1.00 11.67 ? 358 GLU A N 1 ATOM 2810 C CA . GLU A 1 358 ? 33.631 49.160 32.075 1.00 12.69 ? 358 GLU A CA 1 ATOM 2811 C C . GLU A 1 358 ? 32.599 48.621 33.114 1.00 13.58 ? 358 GLU A C 1 ATOM 2812 O O . GLU A 1 358 ? 32.483 47.413 33.294 1.00 13.51 ? 358 GLU A O 1 ATOM 2813 C CB . GLU A 1 358 ? 34.886 49.545 32.821 1.00 13.77 ? 358 GLU A CB 1 ATOM 2814 C CG . GLU A 1 358 ? 36.233 49.684 32.012 1.00 19.67 ? 358 GLU A CG 1 ATOM 2815 C CD . GLU A 1 358 ? 37.375 50.187 32.930 1.00 19.18 ? 358 GLU A CD 1 ATOM 2816 O OE1 . GLU A 1 358 ? 37.160 50.280 34.177 1.00 32.93 ? 358 GLU A OE1 1 ATOM 2817 O OE2 . GLU A 1 358 ? 38.495 50.487 32.482 1.00 24.22 ? 358 GLU A OE2 1 ATOM 2818 N N A ARG A 1 359 ? 31.800 49.501 33.707 0.50 11.44 ? 359 ARG A N 1 ATOM 2819 N N B ARG A 1 359 ? 31.800 49.501 33.707 0.50 13.06 ? 359 ARG A N 1 ATOM 2820 C CA A ARG A 1 359 ? 30.808 48.995 34.667 0.50 13.99 ? 359 ARG A CA 1 ATOM 2821 C CA B ARG A 1 359 ? 30.808 48.995 34.667 0.50 15.93 ? 359 ARG A CA 1 ATOM 2822 C C A ARG A 1 359 ? 29.716 48.210 33.910 0.50 13.58 ? 359 ARG A C 1 ATOM 2823 C C B ARG A 1 359 ? 29.716 48.210 33.910 0.50 14.80 ? 359 ARG A C 1 ATOM 2824 O O A ARG A 1 359 ? 29.196 47.185 34.405 0.50 13.52 ? 359 ARG A O 1 ATOM 2825 O O B ARG A 1 359 ? 29.196 47.185 34.405 0.50 14.25 ? 359 ARG A O 1 ATOM 2826 C CB A ARG A 1 359 ? 30.172 50.152 35.413 0.50 11.48 ? 359 ARG A CB 1 ATOM 2827 C CB B ARG A 1 359 ? 30.172 50.152 35.413 0.50 16.55 ? 359 ARG A CB 1 ATOM 2828 C CG A ARG A 1 359 ? 31.082 50.830 36.432 0.50 14.74 ? 359 ARG A CG 1 ATOM 2829 C CG B ARG A 1 359 ? 31.082 50.830 36.432 0.50 21.37 ? 359 ARG A CG 1 ATOM 2830 C CD A ARG A 1 359 ? 30.330 52.066 36.945 0.50 20.90 ? 359 ARG A CD 1 ATOM 2831 C CD B ARG A 1 359 ? 30.330 52.066 36.945 0.50 27.70 ? 359 ARG A CD 1 ATOM 2832 N NE A ARG A 1 359 ? 31.143 52.986 37.766 0.50 22.96 ? 359 ARG A NE 1 ATOM 2833 N NE B ARG A 1 359 ? 30.903 52.675 38.162 0.50 31.71 ? 359 ARG A NE 1 ATOM 2834 C CZ A ARG A 1 359 ? 31.138 54.318 37.607 0.50 25.33 ? 359 ARG A CZ 1 ATOM 2835 C CZ B ARG A 1 359 ? 30.955 52.049 39.347 0.50 33.87 ? 359 ARG A CZ 1 ATOM 2836 N NH1 A ARG A 1 359 ? 30.379 54.931 36.649 0.50 16.71 ? 359 ARG A NH1 1 ATOM 2837 N NH1 B ARG A 1 359 ? 30.461 50.786 39.522 0.50 34.53 ? 359 ARG A NH1 1 ATOM 2838 N NH2 A ARG A 1 359 ? 31.890 55.050 38.430 0.50 31.56 ? 359 ARG A NH2 1 ATOM 2839 N NH2 B ARG A 1 359 ? 31.525 52.688 40.370 0.50 35.51 ? 359 ARG A NH2 1 ATOM 2840 N N . LEU A 1 360 ? 29.338 48.657 32.716 1.00 12.25 ? 360 LEU A N 1 ATOM 2841 C CA . LEU A 1 360 ? 28.342 47.936 31.935 1.00 11.60 ? 360 LEU A CA 1 ATOM 2842 C C . LEU A 1 360 ? 28.942 46.578 31.543 1.00 11.70 ? 360 LEU A C 1 ATOM 2843 O O . LEU A 1 360 ? 28.260 45.517 31.696 1.00 13.60 ? 360 LEU A O 1 ATOM 2844 C CB . LEU A 1 360 ? 27.934 48.746 30.696 1.00 13.04 ? 360 LEU A CB 1 ATOM 2845 C CG . LEU A 1 360 ? 27.083 49.969 31.058 1.00 11.76 ? 360 LEU A CG 1 ATOM 2846 C CD1 . LEU A 1 360 ? 27.153 50.968 29.908 1.00 15.17 ? 360 LEU A CD1 1 ATOM 2847 C CD2 . LEU A 1 360 ? 25.587 49.624 31.266 1.00 14.66 ? 360 LEU A CD2 1 ATOM 2848 N N . PHE A 1 361 ? 30.180 46.484 31.066 1.00 11.57 ? 361 PHE A N 1 ATOM 2849 C CA . PHE A 1 361 ? 30.732 45.202 30.664 1.00 13.05 ? 361 PHE A CA 1 ATOM 2850 C C . PHE A 1 361 ? 30.787 44.235 31.862 1.00 14.71 ? 361 PHE A C 1 ATOM 2851 O O . PHE A 1 361 ? 30.503 43.055 31.712 1.00 14.24 ? 361 PHE A O 1 ATOM 2852 C CB . PHE A 1 361 ? 32.168 45.356 30.141 1.00 11.70 ? 361 PHE A CB 1 ATOM 2853 C CG . PHE A 1 361 ? 32.294 46.193 28.878 1.00 12.98 ? 361 PHE A CG 1 ATOM 2854 C CD1 . PHE A 1 361 ? 33.531 46.770 28.601 1.00 11.76 ? 361 PHE A CD1 1 ATOM 2855 C CD2 . PHE A 1 361 ? 31.232 46.397 27.993 1.00 11.78 ? 361 PHE A CD2 1 ATOM 2856 C CE1 . PHE A 1 361 ? 33.732 47.561 27.421 1.00 12.35 ? 361 PHE A CE1 1 ATOM 2857 C CE2 . PHE A 1 361 ? 31.414 47.181 26.818 1.00 12.74 ? 361 PHE A CE2 1 ATOM 2858 C CZ . PHE A 1 361 ? 32.692 47.743 26.581 1.00 12.06 ? 361 PHE A CZ 1 ATOM 2859 N N . GLU A 1 362 ? 31.239 44.718 33.027 1.00 14.99 ? 362 GLU A N 1 ATOM 2860 C CA . GLU A 1 362 ? 31.382 43.822 34.170 1.00 14.12 ? 362 GLU A CA 1 ATOM 2861 C C . GLU A 1 362 ? 29.995 43.259 34.505 1.00 13.08 ? 362 GLU A C 1 ATOM 2862 O O . GLU A 1 362 ? 29.919 42.022 34.739 1.00 16.39 ? 362 GLU A O 1 ATOM 2863 C CB . GLU A 1 362 ? 31.936 44.525 35.407 1.00 17.89 ? 362 GLU A CB 1 ATOM 2864 C CG . GLU A 1 362 ? 32.122 43.401 36.526 1.00 21.42 ? 362 GLU A CG 1 ATOM 2865 C CD . GLU A 1 362 ? 32.596 43.933 37.884 1.00 30.58 ? 362 GLU A CD 1 ATOM 2866 O OE1 . GLU A 1 362 ? 33.163 45.038 37.915 1.00 30.21 ? 362 GLU A OE1 1 ATOM 2867 O OE2 . GLU A 1 362 ? 32.409 43.230 38.918 1.00 31.51 ? 362 GLU A OE2 1 ATOM 2868 N N . HIS A 1 363 ? 28.943 44.044 34.476 1.00 13.35 ? 363 HIS A N 1 ATOM 2869 C CA . HIS A 1 363 ? 27.621 43.517 34.773 1.00 14.97 ? 363 HIS A CA 1 ATOM 2870 C C . HIS A 1 363 ? 27.122 42.570 33.701 1.00 15.07 ? 363 HIS A C 1 ATOM 2871 O O . HIS A 1 363 ? 26.766 41.402 33.963 1.00 16.73 ? 363 HIS A O 1 ATOM 2872 C CB . HIS A 1 363 ? 26.636 44.645 34.974 1.00 15.74 ? 363 HIS A CB 1 ATOM 2873 C CG . HIS A 1 363 ? 25.236 44.179 35.282 1.00 15.17 ? 363 HIS A CG 1 ATOM 2874 N ND1 . HIS A 1 363 ? 24.874 43.650 36.521 1.00 23.82 ? 363 HIS A ND1 1 ATOM 2875 C CD2 . HIS A 1 363 ? 24.138 44.107 34.499 1.00 18.80 ? 363 HIS A CD2 1 ATOM 2876 C CE1 . HIS A 1 363 ? 23.609 43.259 36.453 1.00 20.43 ? 363 HIS A CE1 1 ATOM 2877 N NE2 . HIS A 1 363 ? 23.136 43.522 35.248 1.00 22.25 ? 363 HIS A NE2 1 ATOM 2878 N N . ILE A 1 364 ? 27.131 43.020 32.444 1.00 14.68 ? 364 ILE A N 1 ATOM 2879 C CA . ILE A 1 364 ? 26.637 42.239 31.339 1.00 13.90 ? 364 ILE A CA 1 ATOM 2880 C C . ILE A 1 364 ? 27.354 40.933 31.212 1.00 12.98 ? 364 ILE A C 1 ATOM 2881 O O . ILE A 1 364 ? 26.662 39.862 31.068 1.00 15.20 ? 364 ILE A O 1 ATOM 2882 C CB . ILE A 1 364 ? 26.744 43.040 29.998 1.00 12.57 ? 364 ILE A CB 1 ATOM 2883 C CG1 . ILE A 1 364 ? 25.740 44.171 30.052 1.00 13.20 ? 364 ILE A CG1 1 ATOM 2884 C CG2 . ILE A 1 364 ? 26.501 42.093 28.802 1.00 14.27 ? 364 ILE A CG2 1 ATOM 2885 C CD1 . ILE A 1 364 ? 26.020 45.313 29.026 1.00 14.30 ? 364 ILE A CD1 1 ATOM 2886 N N . ASN A 1 365 ? 28.660 40.924 31.293 1.00 12.94 ? 365 ASN A N 1 ATOM 2887 C CA . ASN A 1 365 ? 29.446 39.704 31.071 1.00 14.25 ? 365 ASN A CA 1 ATOM 2888 C C . ASN A 1 365 ? 29.294 38.660 32.185 1.00 17.65 ? 365 ASN A C 1 ATOM 2889 O O . ASN A 1 365 ? 29.557 37.464 31.974 1.00 17.77 ? 365 ASN A O 1 ATOM 2890 C CB . ASN A 1 365 ? 30.928 40.011 30.857 1.00 13.45 ? 365 ASN A CB 1 ATOM 2891 C CG . ASN A 1 365 ? 31.166 40.853 29.590 1.00 12.70 ? 365 ASN A CG 1 ATOM 2892 O OD1 . ASN A 1 365 ? 30.248 41.047 28.762 1.00 14.57 ? 365 ASN A OD1 1 ATOM 2893 N ND2 . ASN A 1 365 ? 32.385 41.346 29.463 1.00 13.35 ? 365 ASN A ND2 1 ATOM 2894 N N . SER A 1 366 ? 28.851 39.142 33.352 1.00 18.57 ? 366 SER A N 1 ATOM 2895 C CA . SER A 1 366 ? 28.660 38.244 34.529 1.00 20.90 ? 366 SER A CA 1 ATOM 2896 C C . SER A 1 366 ? 27.227 37.753 34.649 1.00 23.06 ? 366 SER A C 1 ATOM 2897 O O . SER A 1 366 ? 26.970 36.858 35.481 1.00 26.54 ? 366 SER A O 1 ATOM 2898 C CB . SER A 1 366 ? 29.085 38.998 35.817 1.00 22.95 ? 366 SER A CB 1 ATOM 2899 O OG . SER A 1 366 ? 28.088 39.952 36.138 1.00 25.56 ? 366 SER A OG 1 ATOM 2900 N N . GLN A 1 367 ? 26.287 38.303 33.896 1.00 24.37 ? 367 GLN A N 1 ATOM 2901 C CA . GLN A 1 367 ? 24.866 37.933 33.935 1.00 24.77 ? 367 GLN A CA 1 ATOM 2902 C C . GLN A 1 367 ? 24.580 36.933 32.800 1.00 25.95 ? 367 GLN A C 1 ATOM 2903 O O . GLN A 1 367 ? 24.251 37.328 31.672 1.00 22.13 ? 367 GLN A O 1 ATOM 2904 C CB . GLN A 1 367 ? 23.946 39.164 33.738 1.00 27.05 ? 367 GLN A CB 1 ATOM 2905 C CG . GLN A 1 367 ? 23.870 40.128 34.935 1.00 32.35 ? 367 GLN A CG 1 ATOM 2906 C CD . GLN A 1 367 ? 23.327 39.422 36.159 1.00 35.96 ? 367 GLN A CD 1 ATOM 2907 O OE1 . GLN A 1 367 ? 22.154 39.069 36.198 1.00 36.74 ? 367 GLN A OE1 1 ATOM 2908 N NE2 . GLN A 1 367 ? 24.194 39.187 37.160 1.00 39.85 ? 367 GLN A NE2 1 ATOM 2909 N N . ALA A 1 368 ? 24.650 35.632 33.108 1.00 24.51 ? 368 ALA A N 1 ATOM 2910 C CA . ALA A 1 368 ? 24.420 34.642 32.045 1.00 21.36 ? 368 ALA A CA 1 ATOM 2911 C C . ALA A 1 368 ? 23.171 34.817 31.192 1.00 21.81 ? 368 ALA A C 1 ATOM 2912 O O . ALA A 1 368 ? 23.224 34.511 29.972 1.00 21.47 ? 368 ALA A O 1 ATOM 2913 C CB . ALA A 1 368 ? 24.438 33.204 32.644 1.00 23.74 ? 368 ALA A CB 1 ATOM 2914 N N . HIS A 1 369 ? 22.056 35.293 31.762 1.00 20.41 ? 369 HIS A N 1 ATOM 2915 C CA . HIS A 1 369 ? 20.835 35.432 30.977 1.00 20.04 ? 369 HIS A CA 1 ATOM 2916 C C . HIS A 1 369 ? 20.973 36.322 29.713 1.00 18.11 ? 369 HIS A C 1 ATOM 2917 O O . HIS A 1 369 ? 20.155 36.254 28.816 1.00 20.95 ? 369 HIS A O 1 ATOM 2918 C CB . HIS A 1 369 ? 19.657 35.931 31.870 1.00 23.91 ? 369 HIS A CB 1 ATOM 2919 C CG . HIS A 1 369 ? 19.831 37.321 32.410 1.00 27.22 ? 369 HIS A CG 1 ATOM 2920 N ND1 . HIS A 1 369 ? 19.403 38.439 31.727 1.00 29.81 ? 369 HIS A ND1 1 ATOM 2921 C CD2 . HIS A 1 369 ? 20.447 37.774 33.526 1.00 29.75 ? 369 HIS A CD2 1 ATOM 2922 C CE1 . HIS A 1 369 ? 19.759 39.524 32.395 1.00 25.68 ? 369 HIS A CE1 1 ATOM 2923 N NE2 . HIS A 1 369 ? 20.396 39.148 33.490 1.00 29.72 ? 369 HIS A NE2 1 ATOM 2924 N N . PHE A 1 370 ? 21.971 37.208 29.708 1.00 22.07 ? 370 PHE A N 1 ATOM 2925 C CA . PHE A 1 370 ? 22.159 38.054 28.501 1.00 19.40 ? 370 PHE A CA 1 ATOM 2926 C C . PHE A 1 370 ? 22.846 37.277 27.379 1.00 16.15 ? 370 PHE A C 1 ATOM 2927 O O . PHE A 1 370 ? 22.653 37.588 26.218 1.00 16.62 ? 370 PHE A O 1 ATOM 2928 C CB . PHE A 1 370 ? 23.051 39.265 28.784 1.00 22.17 ? 370 PHE A CB 1 ATOM 2929 C CG . PHE A 1 370 ? 22.383 40.360 29.552 1.00 21.06 ? 370 PHE A CG 1 ATOM 2930 C CD1 . PHE A 1 370 ? 22.979 40.830 30.685 1.00 22.42 ? 370 PHE A CD1 1 ATOM 2931 C CD2 . PHE A 1 370 ? 21.210 40.948 29.104 1.00 20.89 ? 370 PHE A CD2 1 ATOM 2932 C CE1 . PHE A 1 370 ? 22.405 41.902 31.387 1.00 23.67 ? 370 PHE A CE1 1 ATOM 2933 C CE2 . PHE A 1 370 ? 20.643 42.032 29.803 1.00 26.27 ? 370 PHE A CE2 1 ATOM 2934 C CZ . PHE A 1 370 ? 21.261 42.481 30.933 1.00 22.16 ? 370 PHE A CZ 1 ATOM 2935 N N . ASN A 1 371 ? 23.695 36.340 27.753 1.00 14.53 ? 371 ASN A N 1 ATOM 2936 C CA . ASN A 1 371 ? 24.451 35.536 26.804 1.00 14.17 ? 371 ASN A CA 1 ATOM 2937 C C . ASN A 1 371 ? 25.247 36.447 25.876 1.00 13.40 ? 371 ASN A C 1 ATOM 2938 O O . ASN A 1 371 ? 25.276 36.239 24.657 1.00 14.09 ? 371 ASN A O 1 ATOM 2939 C CB . ASN A 1 371 ? 23.518 34.575 26.002 1.00 16.51 ? 371 ASN A CB 1 ATOM 2940 C CG . ASN A 1 371 ? 22.857 33.507 26.937 1.00 15.44 ? 371 ASN A CG 1 ATOM 2941 O OD1 . ASN A 1 371 ? 23.554 32.673 27.508 1.00 20.11 ? 371 ASN A OD1 1 ATOM 2942 N ND2 . ASN A 1 371 ? 21.554 33.622 27.114 1.00 20.62 ? 371 ASN A ND2 1 ATOM 2943 N N . VAL A 1 372 ? 25.931 37.395 26.501 1.00 13.49 ? 372 VAL A N 1 ATOM 2944 C CA . VAL A 1 372 ? 26.747 38.374 25.767 1.00 12.33 ? 372 VAL A CA 1 ATOM 2945 C C . VAL A 1 372 ? 28.119 38.451 26.404 1.00 13.72 ? 372 VAL A C 1 ATOM 2946 O O . VAL A 1 372 ? 28.258 38.388 27.653 1.00 14.48 ? 372 VAL A O 1 ATOM 2947 C CB . VAL A 1 372 ? 26.109 39.803 25.878 1.00 13.02 ? 372 VAL A CB 1 ATOM 2948 C CG1 . VAL A 1 372 ? 27.124 40.894 25.343 1.00 13.07 ? 372 VAL A CG1 1 ATOM 2949 C CG2 . VAL A 1 372 ? 24.803 39.881 25.094 1.00 14.10 ? 372 VAL A CG2 1 ATOM 2950 N N . GLN A 1 373 ? 29.174 38.625 25.583 1.00 13.12 ? 373 GLN A N 1 ATOM 2951 C CA . GLN A 1 373 ? 30.545 38.898 26.066 1.00 12.42 ? 373 GLN A CA 1 ATOM 2952 C C . GLN A 1 373 ? 30.939 40.205 25.342 1.00 12.15 ? 373 GLN A C 1 ATOM 2953 O O . GLN A 1 373 ? 31.149 40.202 24.104 1.00 12.53 ? 373 GLN A O 1 ATOM 2954 C CB . GLN A 1 373 ? 31.496 37.767 25.707 1.00 14.02 ? 373 GLN A CB 1 ATOM 2955 C CG . GLN A 1 373 ? 32.977 38.092 26.040 1.00 15.02 ? 373 GLN A CG 1 ATOM 2956 C CD . GLN A 1 373 ? 33.219 38.400 27.545 1.00 18.52 ? 373 GLN A CD 1 ATOM 2957 O OE1 . GLN A 1 373 ? 32.524 37.860 28.435 1.00 20.01 ? 373 GLN A OE1 1 ATOM 2958 N NE2 . GLN A 1 373 ? 34.204 39.236 27.830 1.00 18.81 ? 373 GLN A NE2 1 ATOM 2959 N N . ALA A 1 374 ? 31.022 41.309 26.072 1.00 11.10 ? 374 ALA A N 1 ATOM 2960 C CA . ALA A 1 374 ? 31.309 42.624 25.494 1.00 10.62 ? 374 ALA A CA 1 ATOM 2961 C C . ALA A 1 374 ? 32.642 43.146 25.958 1.00 10.84 ? 374 ALA A C 1 ATOM 2962 O O . ALA A 1 374 ? 32.998 42.977 27.148 1.00 11.73 ? 374 ALA A O 1 ATOM 2963 C CB . ALA A 1 374 ? 30.233 43.563 25.889 1.00 11.10 ? 374 ALA A CB 1 ATOM 2964 N N . GLN A 1 375 ? 33.367 43.859 25.090 1.00 11.03 ? 375 GLN A N 1 ATOM 2965 C CA . GLN A 1 375 ? 34.685 44.406 25.461 1.00 11.00 ? 375 GLN A CA 1 ATOM 2966 C C . GLN A 1 375 ? 35.070 45.503 24.483 1.00 10.83 ? 375 GLN A C 1 ATOM 2967 O O . GLN A 1 375 ? 34.471 45.613 23.400 1.00 11.82 ? 375 GLN A O 1 ATOM 2968 C CB . GLN A 1 375 ? 35.763 43.347 25.358 1.00 12.58 ? 375 GLN A CB 1 ATOM 2969 C CG . GLN A 1 375 ? 35.776 42.566 24.052 1.00 16.99 ? 375 GLN A CG 1 ATOM 2970 C CD . GLN A 1 375 ? 34.947 41.250 24.162 1.00 25.35 ? 375 GLN A CD 1 ATOM 2971 O OE1 . GLN A 1 375 ? 35.199 40.408 25.061 1.00 26.67 ? 375 GLN A OE1 1 ATOM 2972 N NE2 . GLN A 1 375 ? 33.940 41.067 23.265 1.00 22.50 ? 375 GLN A NE2 1 ATOM 2973 N N . PHE A 1 376 ? 36.014 46.331 24.912 1.00 10.54 ? 376 PHE A N 1 ATOM 2974 C CA . PHE A 1 376 ? 36.587 47.294 23.958 1.00 9.77 ? 376 PHE A CA 1 ATOM 2975 C C . PHE A 1 376 ? 37.393 46.476 22.979 1.00 12.29 ? 376 PHE A C 1 ATOM 2976 O O . PHE A 1 376 ? 38.071 45.500 23.330 1.00 12.57 ? 376 PHE A O 1 ATOM 2977 C CB . PHE A 1 376 ? 37.543 48.248 24.677 1.00 10.76 ? 376 PHE A CB 1 ATOM 2978 C CG . PHE A 1 376 ? 36.857 49.178 25.615 1.00 10.78 ? 376 PHE A CG 1 ATOM 2979 C CD1 . PHE A 1 376 ? 37.230 49.203 26.968 1.00 11.89 ? 376 PHE A CD1 1 ATOM 2980 C CD2 . PHE A 1 376 ? 35.834 50.015 25.175 1.00 11.06 ? 376 PHE A CD2 1 ATOM 2981 C CE1 . PHE A 1 376 ? 36.568 50.072 27.870 1.00 12.56 ? 376 PHE A CE1 1 ATOM 2982 C CE2 . PHE A 1 376 ? 35.180 50.891 26.138 1.00 13.76 ? 376 PHE A CE2 1 ATOM 2983 C CZ . PHE A 1 376 ? 35.581 50.891 27.459 1.00 14.25 ? 376 PHE A CZ 1 ATOM 2984 N N . GLY A 1 377 ? 37.371 46.930 21.729 1.00 10.60 ? 377 GLY A N 1 ATOM 2985 C CA . GLY A 1 377 ? 38.162 46.242 20.709 1.00 11.16 ? 377 GLY A CA 1 ATOM 2986 C C . GLY A 1 377 ? 38.583 47.223 19.628 1.00 10.52 ? 377 GLY A C 1 ATOM 2987 O O . GLY A 1 377 ? 38.251 48.397 19.661 1.00 10.58 ? 377 GLY A O 1 ATOM 2988 N N . THR A 1 378 ? 39.359 46.677 18.672 1.00 11.80 ? 378 THR A N 1 ATOM 2989 C CA . THR A 1 378 ? 39.786 47.464 17.505 1.00 11.04 ? 378 THR A CA 1 ATOM 2990 C C . THR A 1 378 ? 39.017 46.913 16.303 1.00 10.95 ? 378 THR A C 1 ATOM 2991 O O . THR A 1 378 ? 38.307 45.873 16.329 1.00 11.18 ? 378 THR A O 1 ATOM 2992 C CB . THR A 1 378 ? 41.289 47.367 17.241 1.00 12.14 ? 378 THR A CB 1 ATOM 2993 O OG1 . THR A 1 378 ? 41.589 46.007 16.896 1.00 12.85 ? 378 THR A OG1 1 ATOM 2994 C CG2 . THR A 1 378 ? 42.117 47.786 18.476 1.00 14.90 ? 378 THR A CG2 1 ATOM 2995 N N . LEU A 1 379 ? 39.161 47.640 15.188 1.00 10.32 ? 379 LEU A N 1 ATOM 2996 C CA . LEU A 1 379 ? 38.502 47.210 13.969 1.00 9.40 ? 379 LEU A CA 1 ATOM 2997 C C . LEU A 1 379 ? 38.990 45.844 13.459 1.00 8.93 ? 379 LEU A C 1 ATOM 2998 O O . LEU A 1 379 ? 38.193 44.993 13.032 1.00 9.93 ? 379 LEU A O 1 ATOM 2999 C CB . LEU A 1 379 ? 38.651 48.323 12.895 1.00 9.86 ? 379 LEU A CB 1 ATOM 3000 C CG . LEU A 1 379 ? 37.893 48.059 11.590 1.00 9.81 ? 379 LEU A CG 1 ATOM 3001 C CD1 . LEU A 1 379 ? 36.379 48.044 11.864 1.00 12.56 ? 379 LEU A CD1 1 ATOM 3002 C CD2 . LEU A 1 379 ? 38.331 49.147 10.553 1.00 11.51 ? 379 LEU A CD2 1 ATOM 3003 N N . GLN A 1 380 ? 40.305 45.632 13.470 1.00 9.91 ? 380 GLN A N 1 ATOM 3004 C CA . GLN A 1 380 ? 40.841 44.361 13.005 1.00 11.33 ? 380 GLN A CA 1 ATOM 3005 C C . GLN A 1 380 ? 40.358 43.223 13.916 1.00 11.77 ? 380 GLN A C 1 ATOM 3006 O O . GLN A 1 380 ? 40.117 42.118 13.422 1.00 10.31 ? 380 GLN A O 1 ATOM 3007 C CB . GLN A 1 380 ? 42.381 44.400 12.950 1.00 12.85 ? 380 GLN A CB 1 ATOM 3008 C CG . GLN A 1 380 ? 43.020 43.107 12.409 1.00 16.48 ? 380 GLN A CG 1 ATOM 3009 C CD . GLN A 1 380 ? 42.684 42.940 10.975 1.00 18.64 ? 380 GLN A CD 1 ATOM 3010 O OE1 . GLN A 1 380 ? 42.805 43.909 10.209 1.00 19.72 ? 380 GLN A OE1 1 ATOM 3011 N NE2 . GLN A 1 380 ? 42.204 41.733 10.580 1.00 20.50 ? 380 GLN A NE2 1 ATOM 3012 N N . GLU A 1 381 ? 40.226 43.464 15.218 1.00 10.97 ? 381 GLU A N 1 ATOM 3013 C CA . GLU A 1 381 ? 39.705 42.392 16.085 1.00 10.67 ? 381 GLU A CA 1 ATOM 3014 C C . GLU A 1 381 ? 38.276 42.009 15.668 1.00 9.54 ? 381 GLU A C 1 ATOM 3015 O O . GLU A 1 381 ? 37.966 40.827 15.684 1.00 12.69 ? 381 GLU A O 1 ATOM 3016 C CB . GLU A 1 381 ? 39.685 42.856 17.550 1.00 11.72 ? 381 GLU A CB 1 ATOM 3017 C CG . GLU A 1 381 ? 41.026 42.913 18.328 1.00 16.19 ? 381 GLU A CG 1 ATOM 3018 C CD . GLU A 1 381 ? 40.658 43.273 19.777 1.00 22.75 ? 381 GLU A CD 1 ATOM 3019 O OE1 . GLU A 1 381 ? 40.629 44.436 20.098 1.00 21.48 ? 381 GLU A OE1 1 ATOM 3020 O OE2 . GLU A 1 381 ? 40.338 42.358 20.617 1.00 29.44 ? 381 GLU A OE2 1 ATOM 3021 N N . TYR A 1 382 ? 37.426 42.988 15.359 1.00 10.31 ? 382 TYR A N 1 ATOM 3022 C CA . TYR A 1 382 ? 36.119 42.664 14.879 1.00 9.63 ? 382 TYR A CA 1 ATOM 3023 C C . TYR A 1 382 ? 36.170 41.765 13.615 1.00 9.83 ? 382 TYR A C 1 ATOM 3024 O O . TYR A 1 382 ? 35.517 40.714 13.539 1.00 9.79 ? 382 TYR A O 1 ATOM 3025 C CB . TYR A 1 382 ? 35.337 43.964 14.528 1.00 10.72 ? 382 TYR A CB 1 ATOM 3026 C CG . TYR A 1 382 ? 34.025 43.715 13.846 1.00 8.87 ? 382 TYR A CG 1 ATOM 3027 C CD1 . TYR A 1 382 ? 32.950 43.116 14.516 1.00 10.41 ? 382 TYR A CD1 1 ATOM 3028 C CD2 . TYR A 1 382 ? 33.884 43.973 12.466 1.00 9.65 ? 382 TYR A CD2 1 ATOM 3029 C CE1 . TYR A 1 382 ? 31.769 42.774 13.839 1.00 10.18 ? 382 TYR A CE1 1 ATOM 3030 C CE2 . TYR A 1 382 ? 32.713 43.650 11.794 1.00 10.64 ? 382 TYR A CE2 1 ATOM 3031 C CZ . TYR A 1 382 ? 31.652 43.041 12.496 1.00 9.53 ? 382 TYR A CZ 1 ATOM 3032 O OH . TYR A 1 382 ? 30.447 42.708 11.891 1.00 10.41 ? 382 TYR A OH 1 ATOM 3033 N N . PHE A 1 383 ? 36.912 42.226 12.599 1.00 8.84 ? 383 PHE A N 1 ATOM 3034 C CA . PHE A 1 383 ? 36.920 41.471 11.342 1.00 7.98 ? 383 PHE A CA 1 ATOM 3035 C C . PHE A 1 383 ? 37.566 40.074 11.580 1.00 9.49 ? 383 PHE A C 1 ATOM 3036 O O . PHE A 1 383 ? 37.079 39.101 10.970 1.00 10.23 ? 383 PHE A O 1 ATOM 3037 C CB . PHE A 1 383 ? 37.704 42.226 10.252 1.00 9.50 ? 383 PHE A CB 1 ATOM 3038 C CG . PHE A 1 383 ? 36.950 43.385 9.632 1.00 9.15 ? 383 PHE A CG 1 ATOM 3039 C CD1 . PHE A 1 383 ? 37.464 44.672 9.703 1.00 9.39 ? 383 PHE A CD1 1 ATOM 3040 C CD2 . PHE A 1 383 ? 35.731 43.177 8.987 1.00 10.45 ? 383 PHE A CD2 1 ATOM 3041 C CE1 . PHE A 1 383 ? 36.749 45.743 9.118 1.00 10.12 ? 383 PHE A CE1 1 ATOM 3042 C CE2 . PHE A 1 383 ? 35.018 44.258 8.397 1.00 10.79 ? 383 PHE A CE2 1 ATOM 3043 C CZ . PHE A 1 383 ? 35.551 45.550 8.475 1.00 10.24 ? 383 PHE A CZ 1 ATOM 3044 N N . ASP A 1 384 ? 38.615 39.973 12.404 1.00 10.17 ? 384 ASP A N 1 ATOM 3045 C CA . ASP A 1 384 ? 39.171 38.637 12.609 1.00 11.47 ? 384 ASP A CA 1 ATOM 3046 C C . ASP A 1 384 ? 38.110 37.710 13.229 1.00 10.98 ? 384 ASP A C 1 ATOM 3047 O O . ASP A 1 384 ? 37.990 36.533 12.818 1.00 12.26 ? 384 ASP A O 1 ATOM 3048 C CB . ASP A 1 384 ? 40.370 38.712 13.566 1.00 13.76 ? 384 ASP A CB 1 ATOM 3049 C CG . ASP A 1 384 ? 41.575 39.331 12.968 1.00 16.87 ? 384 ASP A CG 1 ATOM 3050 O OD1 . ASP A 1 384 ? 41.681 39.473 11.744 1.00 18.24 ? 384 ASP A OD1 1 ATOM 3051 O OD2 . ASP A 1 384 ? 42.451 39.674 13.805 1.00 22.69 ? 384 ASP A OD2 1 ATOM 3052 N N . ALA A 1 385 ? 37.327 38.198 14.179 1.00 10.50 ? 385 ALA A N 1 ATOM 3053 C CA . ALA A 1 385 ? 36.300 37.353 14.785 1.00 11.64 ? 385 ALA A CA 1 ATOM 3054 C C . ALA A 1 385 ? 35.185 37.019 13.784 1.00 12.99 ? 385 ALA A C 1 ATOM 3055 O O . ALA A 1 385 ? 34.687 35.870 13.763 1.00 12.59 ? 385 ALA A O 1 ATOM 3056 C CB . ALA A 1 385 ? 35.714 38.081 15.998 1.00 11.89 ? 385 ALA A CB 1 ATOM 3057 N N . VAL A 1 386 ? 34.781 37.977 12.919 1.00 11.22 ? 386 VAL A N 1 ATOM 3058 C CA . VAL A 1 386 ? 33.770 37.656 11.915 1.00 11.73 ? 386 VAL A CA 1 ATOM 3059 C C . VAL A 1 386 ? 34.253 36.528 11.004 1.00 12.61 ? 386 VAL A C 1 ATOM 3060 O O . VAL A 1 386 ? 33.478 35.566 10.705 1.00 13.17 ? 386 VAL A O 1 ATOM 3061 C CB . VAL A 1 386 ? 33.462 38.930 11.049 1.00 10.00 ? 386 VAL A CB 1 ATOM 3062 C CG1 . VAL A 1 386 ? 32.678 38.594 9.799 1.00 13.85 ? 386 VAL A CG1 1 ATOM 3063 C CG2 . VAL A 1 386 ? 32.725 39.939 11.899 1.00 12.78 ? 386 VAL A CG2 1 ATOM 3064 N N . HIS A 1 387 ? 35.488 36.602 10.543 1.00 11.74 ? 387 HIS A N 1 ATOM 3065 C CA . HIS A 1 387 ? 35.978 35.555 9.644 1.00 12.36 ? 387 HIS A CA 1 ATOM 3066 C C . HIS A 1 387 ? 36.200 34.228 10.376 1.00 14.41 ? 387 HIS A C 1 ATOM 3067 O O . HIS A 1 387 ? 36.124 33.172 9.699 1.00 12.83 ? 387 HIS A O 1 ATOM 3068 C CB . HIS A 1 387 ? 37.218 35.996 8.874 1.00 11.77 ? 387 HIS A CB 1 ATOM 3069 C CG . HIS A 1 387 ? 36.927 37.132 7.939 1.00 12.19 ? 387 HIS A CG 1 ATOM 3070 N ND1 . HIS A 1 387 ? 36.017 37.031 6.910 1.00 15.91 ? 387 HIS A ND1 1 ATOM 3071 C CD2 . HIS A 1 387 ? 37.380 38.412 7.938 1.00 11.56 ? 387 HIS A CD2 1 ATOM 3072 C CE1 . HIS A 1 387 ? 35.932 38.210 6.294 1.00 14.47 ? 387 HIS A CE1 1 ATOM 3073 N NE2 . HIS A 1 387 ? 36.752 39.062 6.900 1.00 13.67 ? 387 HIS A NE2 1 ATOM 3074 N N . GLN A 1 388 ? 36.491 34.253 11.683 1.00 13.35 ? 388 GLN A N 1 ATOM 3075 C CA . GLN A 1 388 ? 36.593 32.974 12.447 1.00 13.37 ? 388 GLN A CA 1 ATOM 3076 C C . GLN A 1 388 ? 35.189 32.356 12.418 1.00 15.06 ? 388 GLN A C 1 ATOM 3077 O O . GLN A 1 388 ? 35.030 31.134 12.221 1.00 16.27 ? 388 GLN A O 1 ATOM 3078 C CB . GLN A 1 388 ? 37.054 33.287 13.841 1.00 14.78 ? 388 GLN A CB 1 ATOM 3079 C CG . GLN A 1 388 ? 38.571 33.549 13.839 1.00 21.76 ? 388 GLN A CG 1 ATOM 3080 C CD . GLN A 1 388 ? 39.118 34.304 15.088 1.00 29.32 ? 388 GLN A CD 1 ATOM 3081 O OE1 . GLN A 1 388 ? 40.319 34.651 15.155 1.00 33.46 ? 388 GLN A OE1 1 ATOM 3082 N NE2 . GLN A 1 388 ? 38.253 34.559 16.066 1.00 31.74 ? 388 GLN A NE2 1 ATOM 3083 N N . ALA A 1 389 ? 34.138 33.141 12.586 1.00 14.51 ? 389 ALA A N 1 ATOM 3084 C CA . ALA A 1 389 ? 32.753 32.627 12.557 1.00 17.60 ? 389 ALA A CA 1 ATOM 3085 C C . ALA A 1 389 ? 32.435 32.062 11.173 1.00 19.74 ? 389 ALA A C 1 ATOM 3086 O O . ALA A 1 389 ? 31.857 30.969 11.053 1.00 20.57 ? 389 ALA A O 1 ATOM 3087 C CB . ALA A 1 389 ? 31.776 33.712 12.930 1.00 15.66 ? 389 ALA A CB 1 ATOM 3088 N N . GLU A 1 390 ? 32.824 32.786 10.111 1.00 17.29 ? 390 GLU A N 1 ATOM 3089 C CA . GLU A 1 390 ? 32.626 32.339 8.720 1.00 18.72 ? 390 GLU A CA 1 ATOM 3090 C C . GLU A 1 390 ? 33.297 30.976 8.501 1.00 19.76 ? 390 GLU A C 1 ATOM 3091 O O . GLU A 1 390 ? 32.679 30.066 7.928 1.00 22.43 ? 390 GLU A O 1 ATOM 3092 C CB . GLU A 1 390 ? 33.240 33.393 7.768 1.00 17.29 ? 390 GLU A CB 1 ATOM 3093 C CG . GLU A 1 390 ? 33.125 33.075 6.269 1.00 19.69 ? 390 GLU A CG 1 ATOM 3094 C CD . GLU A 1 390 ? 33.841 34.119 5.437 1.00 23.53 ? 390 GLU A CD 1 ATOM 3095 O OE1 . GLU A 1 390 ? 34.684 34.844 6.027 1.00 23.05 ? 390 GLU A OE1 1 ATOM 3096 O OE2 . GLU A 1 390 ? 33.572 34.223 4.222 1.00 24.77 ? 390 GLU A OE2 1 ATOM 3097 N N . ARG A 1 391 ? 34.546 30.827 8.948 1.00 19.70 ? 391 ARG A N 1 ATOM 3098 C CA . ARG A 1 391 ? 35.289 29.576 8.763 1.00 22.16 ? 391 ARG A CA 1 ATOM 3099 C C . ARG A 1 391 ? 34.646 28.463 9.600 1.00 22.42 ? 391 ARG A C 1 ATOM 3100 O O . ARG A 1 391 ? 34.720 27.270 9.207 1.00 28.91 ? 391 ARG A O 1 ATOM 3101 C CB . ARG A 1 391 ? 36.772 29.766 9.136 1.00 21.87 ? 391 ARG A CB 1 ATOM 3102 C CG . ARG A 1 391 ? 37.548 30.600 8.127 1.00 28.17 ? 391 ARG A CG 1 ATOM 3103 C CD . ARG A 1 391 ? 39.040 30.505 8.361 1.00 29.66 ? 391 ARG A CD 1 ATOM 3104 N NE . ARG A 1 391 ? 39.494 31.032 9.652 1.00 35.31 ? 391 ARG A NE 1 ATOM 3105 C CZ . ARG A 1 391 ? 39.700 32.332 9.905 1.00 31.48 ? 391 ARG A CZ 1 ATOM 3106 N NH1 . ARG A 1 391 ? 39.489 33.247 8.966 1.00 33.79 ? 391 ARG A NH1 1 ATOM 3107 N NH2 . ARG A 1 391 ? 40.143 32.695 11.083 1.00 34.68 ? 391 ARG A NH2 1 ATOM 3108 N N . ALA A 1 392 ? 33.989 28.799 10.695 1.00 23.41 ? 392 ALA A N 1 ATOM 3109 C CA . ALA A 1 392 ? 33.347 27.752 11.512 1.00 25.52 ? 392 ALA A CA 1 ATOM 3110 C C . ALA A 1 392 ? 32.021 27.348 10.833 1.00 27.70 ? 392 ALA A C 1 ATOM 3111 O O . ALA A 1 392 ? 31.266 26.522 11.378 1.00 28.73 ? 392 ALA A O 1 ATOM 3112 C CB . ALA A 1 392 ? 33.084 28.242 12.912 1.00 24.41 ? 392 ALA A CB 1 ATOM 3113 N N . GLY A 1 393 ? 31.728 27.936 9.662 1.00 25.01 ? 393 GLY A N 1 ATOM 3114 C CA . GLY A 1 393 ? 30.511 27.575 8.958 1.00 25.09 ? 393 GLY A CA 1 ATOM 3115 C C . GLY A 1 393 ? 29.286 28.247 9.497 1.00 21.46 ? 393 GLY A C 1 ATOM 3116 O O . GLY A 1 393 ? 28.153 27.869 9.186 1.00 24.25 ? 393 GLY A O 1 ATOM 3117 N N . GLN A 1 394 ? 29.455 29.306 10.280 1.00 22.10 ? 394 GLN A N 1 ATOM 3118 C CA . GLN A 1 394 ? 28.260 29.916 10.778 1.00 24.72 ? 394 GLN A CA 1 ATOM 3119 C C . GLN A 1 394 ? 27.605 30.963 9.902 1.00 21.51 ? 394 GLN A C 1 ATOM 3120 O O . GLN A 1 394 ? 26.456 31.320 10.149 1.00 27.43 ? 394 GLN A O 1 ATOM 3121 C CB . GLN A 1 394 ? 28.455 30.373 12.242 1.00 29.68 ? 394 GLN A CB 1 ATOM 3122 C CG . GLN A 1 394 ? 29.236 31.577 12.492 1.00 32.97 ? 394 GLN A CG 1 ATOM 3123 C CD . GLN A 1 394 ? 28.896 32.180 13.867 1.00 33.27 ? 394 GLN A CD 1 ATOM 3124 O OE1 . GLN A 1 394 ? 29.321 31.675 14.936 1.00 30.04 ? 394 GLN A OE1 1 ATOM 3125 N NE2 . GLN A 1 394 ? 28.131 33.263 13.842 1.00 19.52 ? 394 GLN A NE2 1 ATOM 3126 N N . ALA A 1 395 ? 28.273 31.402 8.826 1.00 19.06 ? 395 ALA A N 1 ATOM 3127 C CA . ALA A 1 395 ? 27.699 32.370 7.911 1.00 19.51 ? 395 ALA A CA 1 ATOM 3128 C C . ALA A 1 395 ? 28.377 32.285 6.528 1.00 18.49 ? 395 ALA A C 1 ATOM 3129 O O . ALA A 1 395 ? 29.521 31.835 6.421 1.00 18.67 ? 395 ALA A O 1 ATOM 3130 C CB . ALA A 1 395 ? 27.880 33.805 8.524 1.00 23.05 ? 395 ALA A CB 1 ATOM 3131 N N . GLU A 1 396 ? 27.674 32.680 5.475 1.00 20.73 ? 396 GLU A N 1 ATOM 3132 C CA . GLU A 1 396 ? 28.282 32.760 4.149 1.00 19.43 ? 396 GLU A CA 1 ATOM 3133 C C . GLU A 1 396 ? 27.848 34.174 3.748 1.00 17.46 ? 396 GLU A C 1 ATOM 3134 O O . GLU A 1 396 ? 26.730 34.626 4.164 1.00 19.82 ? 396 GLU A O 1 ATOM 3135 C CB . GLU A 1 396 ? 27.689 31.717 3.196 1.00 26.13 ? 396 GLU A CB 1 ATOM 3136 C CG . GLU A 1 396 ? 26.200 31.794 3.083 1.00 36.01 ? 396 GLU A CG 1 ATOM 3137 C CD . GLU A 1 396 ? 25.609 30.497 2.544 1.00 41.87 ? 396 GLU A CD 1 ATOM 3138 O OE1 . GLU A 1 396 ? 26.161 29.952 1.557 1.00 44.57 ? 396 GLU A OE1 1 ATOM 3139 O OE2 . GLU A 1 396 ? 24.593 30.025 3.111 1.00 47.30 ? 396 GLU A OE2 1 ATOM 3140 N N . PHE A 1 397 ? 28.701 34.855 2.982 1.00 14.46 ? 397 PHE A N 1 ATOM 3141 C CA . PHE A 1 397 ? 28.395 36.217 2.634 1.00 12.06 ? 397 PHE A CA 1 ATOM 3142 C C . PHE A 1 397 ? 28.072 36.393 1.162 1.00 11.57 ? 397 PHE A C 1 ATOM 3143 O O . PHE A 1 397 ? 28.640 35.710 0.312 1.00 14.35 ? 397 PHE A O 1 ATOM 3144 C CB . PHE A 1 397 ? 29.598 37.110 3.026 1.00 13.34 ? 397 PHE A CB 1 ATOM 3145 C CG . PHE A 1 397 ? 29.875 37.142 4.528 1.00 11.59 ? 397 PHE A CG 1 ATOM 3146 C CD1 . PHE A 1 397 ? 30.964 36.469 5.053 1.00 13.65 ? 397 PHE A CD1 1 ATOM 3147 C CD2 . PHE A 1 397 ? 29.017 37.829 5.372 1.00 11.67 ? 397 PHE A CD2 1 ATOM 3148 C CE1 . PHE A 1 397 ? 31.186 36.471 6.465 1.00 14.95 ? 397 PHE A CE1 1 ATOM 3149 C CE2 . PHE A 1 397 ? 29.233 37.841 6.736 1.00 13.08 ? 397 PHE A CE2 1 ATOM 3150 C CZ . PHE A 1 397 ? 30.321 37.153 7.263 1.00 12.82 ? 397 PHE A CZ 1 ATOM 3151 N N . PRO A 1 398 ? 27.170 37.303 0.888 1.00 10.15 ? 398 PRO A N 1 ATOM 3152 C CA . PRO A 1 398 ? 26.781 37.601 -0.499 1.00 11.18 ? 398 PRO A CA 1 ATOM 3153 C C . PRO A 1 398 ? 27.860 38.368 -1.263 1.00 10.12 ? 398 PRO A C 1 ATOM 3154 O O . PRO A 1 398 ? 28.726 39.040 -0.654 1.00 10.89 ? 398 PRO A O 1 ATOM 3155 C CB . PRO A 1 398 ? 25.521 38.422 -0.324 1.00 13.34 ? 398 PRO A CB 1 ATOM 3156 C CG . PRO A 1 398 ? 25.806 39.209 0.971 1.00 12.25 ? 398 PRO A CG 1 ATOM 3157 C CD . PRO A 1 398 ? 26.448 38.145 1.839 1.00 12.11 ? 398 PRO A CD 1 ATOM 3158 N N . THR A 1 399 ? 27.835 38.250 -2.548 1.00 10.04 ? 399 THR A N 1 ATOM 3159 C CA . THR A 1 399 ? 28.759 38.960 -3.459 1.00 9.26 ? 399 THR A CA 1 ATOM 3160 C C . THR A 1 399 ? 27.976 40.191 -3.967 1.00 9.82 ? 399 THR A C 1 ATOM 3161 O O . THR A 1 399 ? 26.768 40.181 -4.130 1.00 10.23 ? 399 THR A O 1 ATOM 3162 C CB . THR A 1 399 ? 29.168 38.071 -4.630 1.00 11.19 ? 399 THR A CB 1 ATOM 3163 O OG1 . THR A 1 399 ? 27.976 37.645 -5.307 1.00 12.27 ? 399 THR A OG1 1 ATOM 3164 C CG2 . THR A 1 399 ? 29.948 36.851 -4.108 1.00 11.81 ? 399 THR A CG2 1 ATOM 3165 N N . LEU A 1 400 ? 28.710 41.293 -4.219 1.00 8.82 ? 400 LEU A N 1 ATOM 3166 C CA . LEU A 1 400 ? 28.092 42.529 -4.656 1.00 7.48 ? 400 LEU A CA 1 ATOM 3167 C C . LEU A 1 400 ? 29.004 43.240 -5.627 1.00 8.51 ? 400 LEU A C 1 ATOM 3168 O O . LEU A 1 400 ? 30.249 43.208 -5.492 1.00 8.84 ? 400 LEU A O 1 ATOM 3169 C CB . LEU A 1 400 ? 27.858 43.430 -3.433 1.00 8.91 ? 400 LEU A CB 1 ATOM 3170 C CG . LEU A 1 400 ? 27.179 44.808 -3.660 1.00 8.28 ? 400 LEU A CG 1 ATOM 3171 C CD1 . LEU A 1 400 ? 26.343 45.215 -2.409 1.00 11.52 ? 400 LEU A CD1 1 ATOM 3172 C CD2 . LEU A 1 400 ? 28.213 45.878 -3.971 1.00 8.56 ? 400 LEU A CD2 1 ATOM 3173 N N . SER A 1 401 ? 28.402 43.885 -6.640 1.00 8.21 ? 401 SER A N 1 ATOM 3174 C CA . SER A 1 401 ? 29.189 44.821 -7.473 1.00 8.59 ? 401 SER A CA 1 ATOM 3175 C C . SER A 1 401 ? 28.326 46.067 -7.675 1.00 7.68 ? 401 SER A C 1 ATOM 3176 O O . SER A 1 401 ? 27.085 46.038 -7.478 1.00 7.97 ? 401 SER A O 1 ATOM 3177 C CB . SER A 1 401 ? 29.595 44.235 -8.817 1.00 8.81 ? 401 SER A CB 1 ATOM 3178 O OG . SER A 1 401 ? 28.468 44.217 -9.715 1.00 8.83 ? 401 SER A OG 1 ATOM 3179 N N . GLY A 1 402 ? 28.994 47.163 -8.016 1.00 8.08 ? 402 GLY A N 1 ATOM 3180 C CA . GLY A 1 402 ? 28.347 48.448 -8.210 1.00 8.60 ? 402 GLY A CA 1 ATOM 3181 C C . GLY A 1 402 ? 28.948 49.524 -7.354 1.00 7.69 ? 402 GLY A C 1 ATOM 3182 O O . GLY A 1 402 ? 30.027 49.342 -6.746 1.00 9.73 ? 402 GLY A O 1 ATOM 3183 N N . ASP A 1 403 ? 28.319 50.679 -7.311 1.00 7.51 ? 403 ASP A N 1 ATOM 3184 C CA . ASP A 1 403 ? 28.797 51.810 -6.461 1.00 7.89 ? 403 ASP A CA 1 ATOM 3185 C C . ASP A 1 403 ? 27.655 52.259 -5.554 1.00 8.96 ? 403 ASP A C 1 ATOM 3186 O O . ASP A 1 403 ? 26.535 51.689 -5.567 1.00 9.55 ? 403 ASP A O 1 ATOM 3187 C CB . ASP A 1 403 ? 29.305 52.988 -7.312 1.00 8.17 ? 403 ASP A CB 1 ATOM 3188 C CG . ASP A 1 403 ? 28.219 53.715 -8.054 1.00 11.29 ? 403 ASP A CG 1 ATOM 3189 O OD1 . ASP A 1 403 ? 27.061 53.256 -8.142 1.00 13.31 ? 403 ASP A OD1 1 ATOM 3190 O OD2 . ASP A 1 403 ? 28.569 54.778 -8.566 1.00 13.39 ? 403 ASP A OD2 1 ATOM 3191 N N . PHE A 1 404 ? 27.968 53.259 -4.746 1.00 7.34 ? 404 PHE A N 1 ATOM 3192 C CA . PHE A 1 404 ? 27.036 53.842 -3.790 1.00 7.52 ? 404 PHE A CA 1 ATOM 3193 C C . PHE A 1 404 ? 26.890 55.349 -3.958 1.00 6.81 ? 404 PHE A C 1 ATOM 3194 O O . PHE A 1 404 ? 27.017 56.110 -3.013 1.00 8.05 ? 404 PHE A O 1 ATOM 3195 C CB . PHE A 1 404 ? 27.398 53.450 -2.343 1.00 8.08 ? 404 PHE A CB 1 ATOM 3196 C CG . PHE A 1 404 ? 27.348 51.935 -2.121 1.00 7.29 ? 404 PHE A CG 1 ATOM 3197 C CD1 . PHE A 1 404 ? 28.517 51.175 -2.101 1.00 8.13 ? 404 PHE A CD1 1 ATOM 3198 C CD2 . PHE A 1 404 ? 26.093 51.296 -2.019 1.00 8.66 ? 404 PHE A CD2 1 ATOM 3199 C CE1 . PHE A 1 404 ? 28.439 49.783 -1.975 1.00 9.14 ? 404 PHE A CE1 1 ATOM 3200 C CE2 . PHE A 1 404 ? 26.041 49.872 -1.901 1.00 8.92 ? 404 PHE A CE2 1 ATOM 3201 C CZ . PHE A 1 404 ? 27.184 49.142 -1.873 1.00 9.03 ? 404 PHE A CZ 1 ATOM 3202 N N . PHE A 1 405 ? 26.662 55.728 -5.221 1.00 8.72 ? 405 PHE A N 1 ATOM 3203 C CA . PHE A 1 405 ? 26.293 57.127 -5.541 1.00 7.20 ? 405 PHE A CA 1 ATOM 3204 C C . PHE A 1 405 ? 24.932 57.097 -6.214 1.00 8.88 ? 405 PHE A C 1 ATOM 3205 O O . PHE A 1 405 ? 24.610 56.129 -6.897 1.00 10.56 ? 405 PHE A O 1 ATOM 3206 C CB . PHE A 1 405 ? 27.302 57.770 -6.524 1.00 8.76 ? 405 PHE A CB 1 ATOM 3207 C CG . PHE A 1 405 ? 28.721 57.872 -5.967 1.00 8.18 ? 405 PHE A CG 1 ATOM 3208 C CD1 . PHE A 1 405 ? 29.759 57.161 -6.572 1.00 8.33 ? 405 PHE A CD1 1 ATOM 3209 C CD2 . PHE A 1 405 ? 28.982 58.652 -4.857 1.00 8.88 ? 405 PHE A CD2 1 ATOM 3210 C CE1 . PHE A 1 405 ? 31.093 57.256 -6.008 1.00 8.82 ? 405 PHE A CE1 1 ATOM 3211 C CE2 . PHE A 1 405 ? 30.295 58.735 -4.323 1.00 7.97 ? 405 PHE A CE2 1 ATOM 3212 C CZ . PHE A 1 405 ? 31.319 58.050 -4.879 1.00 8.33 ? 405 PHE A CZ 1 ATOM 3213 N N . THR A 1 406 ? 24.122 58.135 -6.101 1.00 9.16 ? 406 THR A N 1 ATOM 3214 C CA . THR A 1 406 ? 24.351 59.360 -5.339 1.00 8.19 ? 406 THR A CA 1 ATOM 3215 C C . THR A 1 406 ? 23.702 59.236 -3.983 1.00 9.13 ? 406 THR A C 1 ATOM 3216 O O . THR A 1 406 ? 22.534 58.817 -3.823 1.00 9.94 ? 406 THR A O 1 ATOM 3217 C CB . THR A 1 406 ? 23.820 60.579 -6.128 1.00 8.31 ? 406 THR A CB 1 ATOM 3218 O OG1 . THR A 1 406 ? 24.754 60.786 -7.178 1.00 9.71 ? 406 THR A OG1 1 ATOM 3219 C CG2 . THR A 1 406 ? 23.691 61.838 -5.286 1.00 9.60 ? 406 THR A CG2 1 ATOM 3220 N N . TYR A 1 407 ? 24.454 59.579 -2.955 1.00 8.19 ? 407 TYR A N 1 ATOM 3221 C CA . TYR A 1 407 ? 24.019 59.478 -1.593 1.00 8.54 ? 407 TYR A CA 1 ATOM 3222 C C . TYR A 1 407 ? 22.913 60.462 -1.229 1.00 9.00 ? 407 TYR A C 1 ATOM 3223 O O . TYR A 1 407 ? 22.952 61.612 -1.676 1.00 9.35 ? 407 TYR A O 1 ATOM 3224 C CB . TYR A 1 407 ? 25.247 59.788 -0.697 1.00 9.23 ? 407 TYR A CB 1 ATOM 3225 C CG . TYR A 1 407 ? 25.027 59.921 0.783 1.00 7.95 ? 407 TYR A CG 1 ATOM 3226 C CD1 . TYR A 1 407 ? 24.545 58.853 1.560 1.00 9.72 ? 407 TYR A CD1 1 ATOM 3227 C CD2 . TYR A 1 407 ? 25.330 61.098 1.424 1.00 8.58 ? 407 TYR A CD2 1 ATOM 3228 C CE1 . TYR A 1 407 ? 24.382 58.971 2.949 1.00 8.81 ? 407 TYR A CE1 1 ATOM 3229 C CE2 . TYR A 1 407 ? 25.186 61.233 2.813 1.00 10.00 ? 407 TYR A CE2 1 ATOM 3230 C CZ . TYR A 1 407 ? 24.723 60.145 3.562 1.00 9.15 ? 407 TYR A CZ 1 ATOM 3231 O OH . TYR A 1 407 ? 24.729 60.275 4.935 1.00 10.01 ? 407 TYR A OH 1 ATOM 3232 N N . ALA A 1 408 ? 21.967 60.001 -0.411 1.00 10.27 ? 408 ALA A N 1 ATOM 3233 C CA . ALA A 1 408 ? 20.971 60.892 0.251 1.00 10.22 ? 408 ALA A CA 1 ATOM 3234 C C . ALA A 1 408 ? 20.928 60.417 1.693 1.00 10.14 ? 408 ALA A C 1 ATOM 3235 O O . ALA A 1 408 ? 20.836 59.184 1.957 1.00 10.64 ? 408 ALA A O 1 ATOM 3236 C CB . ALA A 1 408 ? 19.543 60.807 -0.389 1.00 10.93 ? 408 ALA A CB 1 ATOM 3237 N N . ASP A 1 409 ? 21.047 61.355 2.633 1.00 9.98 ? 409 ASP A N 1 ATOM 3238 C CA . ASP A 1 409 ? 20.972 60.975 4.057 1.00 10.81 ? 409 ASP A CA 1 ATOM 3239 C C . ASP A 1 409 ? 19.531 61.045 4.596 1.00 11.17 ? 409 ASP A C 1 ATOM 3240 O O . ASP A 1 409 ? 19.263 60.425 5.643 1.00 12.72 ? 409 ASP A O 1 ATOM 3241 C CB . ASP A 1 409 ? 21.872 61.856 4.949 1.00 10.23 ? 409 ASP A CB 1 ATOM 3242 C CG . ASP A 1 409 ? 21.613 63.366 4.839 1.00 9.05 ? 409 ASP A CG 1 ATOM 3243 O OD1 . ASP A 1 409 ? 21.002 63.856 3.865 1.00 10.47 ? 409 ASP A OD1 1 ATOM 3244 O OD2 . ASP A 1 409 ? 22.129 64.070 5.752 1.00 11.38 ? 409 ASP A OD2 1 ATOM 3245 N N . ARG A 1 410 ? 18.625 61.748 3.893 1.00 10.07 ? 410 ARG A N 1 ATOM 3246 C CA . ARG A 1 410 ? 17.203 61.843 4.345 1.00 10.75 ? 410 ARG A CA 1 ATOM 3247 C C . ARG A 1 410 ? 16.420 62.496 3.216 1.00 12.22 ? 410 ARG A C 1 ATOM 3248 O O . ARG A 1 410 ? 16.987 63.219 2.342 1.00 12.85 ? 410 ARG A O 1 ATOM 3249 C CB . ARG A 1 410 ? 17.038 62.646 5.636 1.00 12.28 ? 410 ARG A CB 1 ATOM 3250 C CG . ARG A 1 410 ? 17.509 64.116 5.550 1.00 13.88 ? 410 ARG A CG 1 ATOM 3251 C CD . ARG A 1 410 ? 17.490 64.705 6.959 1.00 18.88 ? 410 ARG A CD 1 ATOM 3252 N NE . ARG A 1 410 ? 18.118 66.030 7.085 1.00 17.44 ? 410 ARG A NE 1 ATOM 3253 C CZ . ARG A 1 410 ? 17.535 67.187 6.810 1.00 21.91 ? 410 ARG A CZ 1 ATOM 3254 N NH1 . ARG A 1 410 ? 16.270 67.211 6.378 1.00 24.17 ? 410 ARG A NH1 1 ATOM 3255 N NH2 . ARG A 1 410 ? 18.230 68.313 6.970 1.00 18.82 ? 410 ARG A NH2 1 ATOM 3256 N N A SER A 1 411 ? 15.124 62.154 3.175 0.50 11.72 ? 411 SER A N 1 ATOM 3257 N N B SER A 1 411 ? 15.124 62.154 3.175 0.50 13.51 ? 411 SER A N 1 ATOM 3258 C CA A SER A 1 411 ? 14.147 62.674 2.193 0.50 11.57 ? 411 SER A CA 1 ATOM 3259 C CA B SER A 1 411 ? 14.147 62.674 2.193 0.50 14.70 ? 411 SER A CA 1 ATOM 3260 C C A SER A 1 411 ? 14.696 62.771 0.790 0.50 11.19 ? 411 SER A C 1 ATOM 3261 C C B SER A 1 411 ? 14.653 62.653 0.771 0.50 14.33 ? 411 SER A C 1 ATOM 3262 O O A SER A 1 411 ? 15.166 61.778 0.238 0.50 10.83 ? 411 SER A O 1 ATOM 3263 O O B SER A 1 411 ? 15.044 61.602 0.267 0.50 18.12 ? 411 SER A O 1 ATOM 3264 C CB A SER A 1 411 ? 13.496 63.978 2.691 0.50 16.46 ? 411 SER A CB 1 ATOM 3265 C CB B SER A 1 411 ? 13.592 64.043 2.630 0.50 18.95 ? 411 SER A CB 1 ATOM 3266 O OG A SER A 1 411 ? 14.419 64.980 2.970 0.50 16.74 ? 411 SER A OG 1 ATOM 3267 O OG B SER A 1 411 ? 12.605 64.531 1.780 0.50 21.50 ? 411 SER A OG 1 ATOM 3268 N N . ASP A 1 412 ? 14.616 63.962 0.183 1.00 11.55 ? 412 ASP A N 1 ATOM 3269 C CA . ASP A 1 412 ? 15.113 64.173 -1.188 1.00 11.48 ? 412 ASP A CA 1 ATOM 3270 C C . ASP A 1 412 ? 16.460 64.946 -1.158 1.00 10.05 ? 412 ASP A C 1 ATOM 3271 O O . ASP A 1 412 ? 16.826 65.535 -2.184 1.00 11.59 ? 412 ASP A O 1 ATOM 3272 C CB . ASP A 1 412 ? 14.080 65.016 -1.985 1.00 12.91 ? 412 ASP A CB 1 ATOM 3273 C CG . ASP A 1 412 ? 13.931 66.440 -1.447 1.00 12.92 ? 412 ASP A CG 1 ATOM 3274 O OD1 . ASP A 1 412 ? 14.399 66.779 -0.363 1.00 13.39 ? 412 ASP A OD1 1 ATOM 3275 O OD2 . ASP A 1 412 ? 13.277 67.271 -2.155 1.00 15.48 ? 412 ASP A OD2 1 ATOM 3276 N N . ASN A 1 413 ? 17.153 64.903 -0.018 1.00 10.43 ? 413 ASN A N 1 ATOM 3277 C CA . ASN A 1 413 ? 18.407 65.662 0.139 1.00 10.95 ? 413 ASN A CA 1 ATOM 3278 C C . ASN A 1 413 ? 19.597 64.801 -0.425 1.00 10.68 ? 413 ASN A C 1 ATOM 3279 O O . ASN A 1 413 ? 20.283 64.095 0.350 1.00 10.38 ? 413 ASN A O 1 ATOM 3280 C CB . ASN A 1 413 ? 18.670 65.975 1.603 1.00 11.11 ? 413 ASN A CB 1 ATOM 3281 C CG . ASN A 1 413 ? 17.738 67.062 2.215 1.00 11.56 ? 413 ASN A CG 1 ATOM 3282 O OD1 . ASN A 1 413 ? 18.006 67.534 3.285 1.00 14.06 ? 413 ASN A OD1 1 ATOM 3283 N ND2 . ASN A 1 413 ? 16.657 67.414 1.525 1.00 11.48 ? 413 ASN A ND2 1 ATOM 3284 N N . TYR A 1 414 ? 19.760 64.858 -1.729 1.00 9.78 ? 414 TYR A N 1 ATOM 3285 C CA . TYR A 1 414 ? 20.854 64.146 -2.465 1.00 9.20 ? 414 TYR A CA 1 ATOM 3286 C C . TYR A 1 414 ? 22.086 65.033 -2.510 1.00 9.72 ? 414 TYR A C 1 ATOM 3287 O O . TYR A 1 414 ? 22.003 66.224 -2.839 1.00 10.60 ? 414 TYR A O 1 ATOM 3288 C CB . TYR A 1 414 ? 20.428 63.778 -3.896 1.00 9.66 ? 414 TYR A CB 1 ATOM 3289 C CG . TYR A 1 414 ? 19.412 62.634 -3.930 1.00 9.97 ? 414 TYR A CG 1 ATOM 3290 C CD1 . TYR A 1 414 ? 18.056 62.860 -3.697 1.00 10.97 ? 414 TYR A CD1 1 ATOM 3291 C CD2 . TYR A 1 414 ? 19.837 61.325 -4.120 1.00 10.90 ? 414 TYR A CD2 1 ATOM 3292 C CE1 . TYR A 1 414 ? 17.135 61.785 -3.653 1.00 11.09 ? 414 TYR A CE1 1 ATOM 3293 C CE2 . TYR A 1 414 ? 18.933 60.233 -4.087 1.00 11.28 ? 414 TYR A CE2 1 ATOM 3294 C CZ . TYR A 1 414 ? 17.587 60.508 -3.850 1.00 10.63 ? 414 TYR A CZ 1 ATOM 3295 O OH . TYR A 1 414 ? 16.717 59.394 -3.817 1.00 11.06 ? 414 TYR A OH 1 ATOM 3296 N N . TRP A 1 415 ? 23.212 64.388 -2.196 1.00 9.25 ? 415 TRP A N 1 ATOM 3297 C CA . TRP A 1 415 ? 24.487 65.115 -2.076 1.00 9.19 ? 415 TRP A CA 1 ATOM 3298 C C . TRP A 1 415 ? 25.178 65.144 -3.429 1.00 9.33 ? 415 TRP A C 1 ATOM 3299 O O . TRP A 1 415 ? 26.320 64.684 -3.565 1.00 11.44 ? 415 TRP A O 1 ATOM 3300 C CB . TRP A 1 415 ? 25.353 64.425 -1.026 1.00 8.53 ? 415 TRP A CB 1 ATOM 3301 C CG . TRP A 1 415 ? 24.791 64.521 0.378 1.00 8.98 ? 415 TRP A CG 1 ATOM 3302 C CD1 . TRP A 1 415 ? 23.443 64.264 0.795 1.00 9.02 ? 415 TRP A CD1 1 ATOM 3303 C CD2 . TRP A 1 415 ? 25.526 64.791 1.571 1.00 9.02 ? 415 TRP A CD2 1 ATOM 3304 N NE1 . TRP A 1 415 ? 23.388 64.364 2.148 1.00 9.32 ? 415 TRP A NE1 1 ATOM 3305 C CE2 . TRP A 1 415 ? 24.634 64.685 2.660 1.00 10.18 ? 415 TRP A CE2 1 ATOM 3306 C CE3 . TRP A 1 415 ? 26.896 65.111 1.840 1.00 8.77 ? 415 TRP A CE3 1 ATOM 3307 C CZ2 . TRP A 1 415 ? 25.033 64.868 3.983 1.00 9.43 ? 415 TRP A CZ2 1 ATOM 3308 C CZ3 . TRP A 1 415 ? 27.296 65.293 3.125 1.00 8.77 ? 415 TRP A CZ3 1 ATOM 3309 C CH2 . TRP A 1 415 ? 26.372 65.165 4.213 1.00 9.45 ? 415 TRP A CH2 1 ATOM 3310 N N . SER A 1 416 ? 24.558 65.733 -4.452 1.00 8.58 ? 416 SER A N 1 ATOM 3311 C CA . SER A 1 416 ? 25.204 65.855 -5.736 1.00 8.94 ? 416 SER A CA 1 ATOM 3312 C C . SER A 1 416 ? 25.801 67.265 -5.959 1.00 7.79 ? 416 SER A C 1 ATOM 3313 O O . SER A 1 416 ? 26.463 67.451 -6.963 1.00 8.45 ? 416 SER A O 1 ATOM 3314 C CB . SER A 1 416 ? 24.250 65.438 -6.871 1.00 8.32 ? 416 SER A CB 1 ATOM 3315 O OG . SER A 1 416 ? 22.947 66.015 -6.699 1.00 9.74 ? 416 SER A OG 1 ATOM 3316 N N . GLY A 1 417 ? 25.570 68.203 -5.051 1.00 7.89 ? 417 GLY A N 1 ATOM 3317 C CA . GLY A 1 417 ? 26.164 69.552 -5.220 1.00 9.29 ? 417 GLY A CA 1 ATOM 3318 C C . GLY A 1 417 ? 27.685 69.526 -5.135 1.00 7.31 ? 417 GLY A C 1 ATOM 3319 O O . GLY A 1 417 ? 28.342 70.229 -5.926 1.00 7.93 ? 417 GLY A O 1 ATOM 3320 N N . TYR A 1 418 ? 28.255 68.697 -4.234 1.00 7.26 ? 418 TYR A N 1 ATOM 3321 C CA . TYR A 1 418 ? 29.711 68.706 -4.086 1.00 6.45 ? 418 TYR A CA 1 ATOM 3322 C C . TYR A 1 418 ? 30.457 68.085 -5.254 1.00 7.39 ? 418 TYR A C 1 ATOM 3323 O O . TYR A 1 418 ? 31.697 68.093 -5.270 1.00 8.19 ? 418 TYR A O 1 ATOM 3324 C CB . TYR A 1 418 ? 30.091 68.033 -2.732 1.00 7.68 ? 418 TYR A CB 1 ATOM 3325 C CG . TYR A 1 418 ? 30.212 66.503 -2.781 1.00 7.39 ? 418 TYR A CG 1 ATOM 3326 C CD1 . TYR A 1 418 ? 31.447 65.906 -2.949 1.00 7.83 ? 418 TYR A CD1 1 ATOM 3327 C CD2 . TYR A 1 418 ? 29.071 65.689 -2.635 1.00 8.45 ? 418 TYR A CD2 1 ATOM 3328 C CE1 . TYR A 1 418 ? 31.586 64.530 -2.980 1.00 6.88 ? 418 TYR A CE1 1 ATOM 3329 C CE2 . TYR A 1 418 ? 29.190 64.284 -2.653 1.00 8.62 ? 418 TYR A CE2 1 ATOM 3330 C CZ . TYR A 1 418 ? 30.462 63.746 -2.825 1.00 7.19 ? 418 TYR A CZ 1 ATOM 3331 O OH . TYR A 1 418 ? 30.651 62.365 -2.797 1.00 8.41 ? 418 TYR A OH 1 ATOM 3332 N N . TYR A 1 419 ? 29.746 67.492 -6.223 1.00 7.38 ? 419 TYR A N 1 ATOM 3333 C CA . TYR A 1 419 ? 30.414 67.053 -7.455 1.00 7.33 ? 419 TYR A CA 1 ATOM 3334 C C . TYR A 1 419 ? 30.923 68.282 -8.263 1.00 6.60 ? 419 TYR A C 1 ATOM 3335 O O . TYR A 1 419 ? 31.774 68.128 -9.140 1.00 7.55 ? 419 TYR A O 1 ATOM 3336 C CB . TYR A 1 419 ? 29.467 66.239 -8.343 1.00 7.48 ? 419 TYR A CB 1 ATOM 3337 C CG . TYR A 1 419 ? 28.806 65.053 -7.688 1.00 6.68 ? 419 TYR A CG 1 ATOM 3338 C CD1 . TYR A 1 419 ? 27.616 64.559 -8.222 1.00 7.17 ? 419 TYR A CD1 1 ATOM 3339 C CD2 . TYR A 1 419 ? 29.397 64.377 -6.589 1.00 8.15 ? 419 TYR A CD2 1 ATOM 3340 C CE1 . TYR A 1 419 ? 27.008 63.408 -7.673 1.00 7.60 ? 419 TYR A CE1 1 ATOM 3341 C CE2 . TYR A 1 419 ? 28.802 63.221 -6.043 1.00 8.41 ? 419 TYR A CE2 1 ATOM 3342 C CZ . TYR A 1 419 ? 27.623 62.761 -6.610 1.00 8.22 ? 419 TYR A CZ 1 ATOM 3343 O OH . TYR A 1 419 ? 27.067 61.599 -6.102 1.00 8.47 ? 419 TYR A OH 1 ATOM 3344 N N . THR A 1 420 ? 30.447 69.490 -7.895 1.00 7.02 ? 420 THR A N 1 ATOM 3345 C CA . THR A 1 420 ? 30.845 70.719 -8.588 1.00 7.82 ? 420 THR A CA 1 ATOM 3346 C C . THR A 1 420 ? 31.371 71.803 -7.692 1.00 7.98 ? 420 THR A C 1 ATOM 3347 O O . THR A 1 420 ? 32.163 72.637 -8.178 1.00 8.87 ? 420 THR A O 1 ATOM 3348 C CB . THR A 1 420 ? 29.603 71.255 -9.405 1.00 7.73 ? 420 THR A CB 1 ATOM 3349 O OG1 . THR A 1 420 ? 29.153 70.182 -10.254 1.00 8.89 ? 420 THR A OG1 1 ATOM 3350 C CG2 . THR A 1 420 ? 29.913 72.494 -10.261 1.00 10.51 ? 420 THR A CG2 1 ATOM 3351 N N . SER A 1 421 ? 30.991 71.860 -6.420 1.00 7.53 ? 421 SER A N 1 ATOM 3352 C CA . SER A 1 421 ? 31.414 72.944 -5.568 1.00 7.94 ? 421 SER A CA 1 ATOM 3353 C C . SER A 1 421 ? 32.893 73.296 -5.615 1.00 8.04 ? 421 SER A C 1 ATOM 3354 O O . SER A 1 421 ? 33.742 72.398 -5.547 1.00 7.67 ? 421 SER A O 1 ATOM 3355 C CB . SER A 1 421 ? 31.031 72.619 -4.123 1.00 7.19 ? 421 SER A CB 1 ATOM 3356 O OG . SER A 1 421 ? 29.616 72.489 -4.009 1.00 8.66 ? 421 SER A OG 1 ATOM 3357 N N . ARG A 1 422 ? 33.190 74.616 -5.638 1.00 7.59 ? 422 ARG A N 1 ATOM 3358 C CA . ARG A 1 422 ? 34.604 75.118 -5.706 1.00 7.30 ? 422 ARG A CA 1 ATOM 3359 C C . ARG A 1 422 ? 35.337 74.446 -6.905 1.00 8.34 ? 422 ARG A C 1 ATOM 3360 O O . ARG A 1 422 ? 36.380 73.741 -6.764 1.00 7.84 ? 422 ARG A O 1 ATOM 3361 C CB . ARG A 1 422 ? 35.373 74.866 -4.398 1.00 8.18 ? 422 ARG A CB 1 ATOM 3362 C CG . ARG A 1 422 ? 35.084 75.916 -3.283 1.00 8.40 ? 422 ARG A CG 1 ATOM 3363 C CD . ARG A 1 422 ? 33.575 76.055 -2.854 1.00 8.57 ? 422 ARG A CD 1 ATOM 3364 N NE . ARG A 1 422 ? 33.538 77.046 -1.743 1.00 9.04 ? 422 ARG A NE 1 ATOM 3365 C CZ . ARG A 1 422 ? 33.607 76.751 -0.464 1.00 9.62 ? 422 ARG A CZ 1 ATOM 3366 N NH1 . ARG A 1 422 ? 33.595 75.493 -0.042 1.00 9.78 ? 422 ARG A NH1 1 ATOM 3367 N NH2 . ARG A 1 422 ? 33.876 77.717 0.432 1.00 9.97 ? 422 ARG A NH2 1 ATOM 3368 N N . PRO A 1 423 ? 34.833 74.652 -8.104 1.00 7.43 ? 423 PRO A N 1 ATOM 3369 C CA . PRO A 1 423 ? 35.431 74.025 -9.288 1.00 7.35 ? 423 PRO A CA 1 ATOM 3370 C C . PRO A 1 423 ? 36.821 74.488 -9.632 1.00 7.34 ? 423 PRO A C 1 ATOM 3371 O O . PRO A 1 423 ? 37.560 73.765 -10.310 1.00 7.92 ? 423 PRO A O 1 ATOM 3372 C CB . PRO A 1 423 ? 34.373 74.269 -10.397 1.00 8.45 ? 423 PRO A CB 1 ATOM 3373 C CG . PRO A 1 423 ? 33.800 75.620 -9.996 1.00 8.72 ? 423 PRO A CG 1 ATOM 3374 C CD . PRO A 1 423 ? 33.681 75.516 -8.466 1.00 7.98 ? 423 PRO A CD 1 ATOM 3375 N N . TYR A 1 424 ? 37.208 75.703 -9.207 1.00 8.74 ? 424 TYR A N 1 ATOM 3376 C CA . TYR A 1 424 ? 38.601 76.132 -9.478 1.00 8.04 ? 424 TYR A CA 1 ATOM 3377 C C . TYR A 1 424 ? 39.587 75.136 -8.862 1.00 6.89 ? 424 TYR A C 1 ATOM 3378 O O . TYR A 1 424 ? 40.564 74.741 -9.507 1.00 7.85 ? 424 TYR A O 1 ATOM 3379 C CB . TYR A 1 424 ? 38.834 77.521 -8.853 1.00 8.44 ? 424 TYR A CB 1 ATOM 3380 C CG . TYR A 1 424 ? 40.221 78.066 -9.086 1.00 8.00 ? 424 TYR A CG 1 ATOM 3381 C CD1 . TYR A 1 424 ? 40.481 78.825 -10.206 1.00 9.87 ? 424 TYR A CD1 1 ATOM 3382 C CD2 . TYR A 1 424 ? 41.259 77.823 -8.198 1.00 8.41 ? 424 TYR A CD2 1 ATOM 3383 C CE1 . TYR A 1 424 ? 41.757 79.350 -10.436 1.00 10.90 ? 424 TYR A CE1 1 ATOM 3384 C CE2 . TYR A 1 424 ? 42.563 78.340 -8.452 1.00 11.84 ? 424 TYR A CE2 1 ATOM 3385 C CZ . TYR A 1 424 ? 42.760 79.097 -9.573 1.00 11.15 ? 424 TYR A CZ 1 ATOM 3386 O OH . TYR A 1 424 ? 44.012 79.680 -9.852 1.00 15.22 ? 424 TYR A OH 1 ATOM 3387 N N . HIS A 1 425 ? 39.308 74.712 -7.634 1.00 7.54 ? 425 HIS A N 1 ATOM 3388 C CA . HIS A 1 425 ? 40.212 73.790 -6.928 1.00 6.99 ? 425 HIS A CA 1 ATOM 3389 C C . HIS A 1 425 ? 40.119 72.382 -7.406 1.00 7.86 ? 425 HIS A C 1 ATOM 3390 O O . HIS A 1 425 ? 41.105 71.610 -7.353 1.00 7.27 ? 425 HIS A O 1 ATOM 3391 C CB . HIS A 1 425 ? 40.007 73.931 -5.398 1.00 9.07 ? 425 HIS A CB 1 ATOM 3392 C CG . HIS A 1 425 ? 40.004 75.365 -4.974 1.00 8.78 ? 425 HIS A CG 1 ATOM 3393 N ND1 . HIS A 1 425 ? 41.141 76.118 -4.680 1.00 13.20 ? 425 HIS A ND1 1 ATOM 3394 C CD2 . HIS A 1 425 ? 38.973 76.227 -4.991 1.00 8.12 ? 425 HIS A CD2 1 ATOM 3395 C CE1 . HIS A 1 425 ? 40.772 77.392 -4.533 1.00 8.68 ? 425 HIS A CE1 1 ATOM 3396 N NE2 . HIS A 1 425 ? 39.470 77.472 -4.718 1.00 12.94 ? 425 HIS A NE2 1 ATOM 3397 N N . LYS A 1 426 ? 38.920 71.991 -7.889 1.00 6.89 ? 426 LYS A N 1 ATOM 3398 C CA . LYS A 1 426 ? 38.769 70.675 -8.538 1.00 7.61 ? 426 LYS A CA 1 ATOM 3399 C C . LYS A 1 426 ? 39.672 70.614 -9.783 1.00 6.66 ? 426 LYS A C 1 ATOM 3400 O O . LYS A 1 426 ? 40.299 69.573 -10.057 1.00 7.68 ? 426 LYS A O 1 ATOM 3401 C CB . LYS A 1 426 ? 37.281 70.485 -8.939 1.00 7.25 ? 426 LYS A CB 1 ATOM 3402 C CG . LYS A 1 426 ? 36.417 70.098 -7.721 1.00 7.26 ? 426 LYS A CG 1 ATOM 3403 C CD . LYS A 1 426 ? 34.889 70.148 -8.072 1.00 8.16 ? 426 LYS A CD 1 ATOM 3404 C CE . LYS A 1 426 ? 34.014 69.227 -7.181 1.00 7.49 ? 426 LYS A CE 1 ATOM 3405 N NZ . LYS A 1 426 ? 34.000 69.668 -5.747 1.00 7.31 ? 426 LYS A NZ 1 ATOM 3406 N N . ARG A 1 427 ? 39.711 71.705 -10.592 1.00 6.32 ? 427 ARG A N 1 ATOM 3407 C CA . ARG A 1 427 ? 40.601 71.717 -11.734 1.00 7.36 ? 427 ARG A CA 1 ATOM 3408 C C . ARG A 1 427 ? 42.078 71.744 -11.288 1.00 8.22 ? 427 ARG A C 1 ATOM 3409 O O . ARG A 1 427 ? 42.896 71.016 -11.861 1.00 7.05 ? 427 ARG A O 1 ATOM 3410 C CB . ARG A 1 427 ? 40.253 72.942 -12.614 1.00 7.53 ? 427 ARG A CB 1 ATOM 3411 C CG . ARG A 1 427 ? 41.209 73.223 -13.741 1.00 9.58 ? 427 ARG A CG 1 ATOM 3412 C CD . ARG A 1 427 ? 41.277 72.076 -14.777 1.00 10.12 ? 427 ARG A CD 1 ATOM 3413 N NE . ARG A 1 427 ? 42.310 72.497 -15.746 1.00 11.34 ? 427 ARG A NE 1 ATOM 3414 C CZ . ARG A 1 427 ? 43.110 71.678 -16.339 1.00 9.95 ? 427 ARG A CZ 1 ATOM 3415 N NH1 . ARG A 1 427 ? 43.080 70.365 -16.180 1.00 10.24 ? 427 ARG A NH1 1 ATOM 3416 N NH2 . ARG A 1 427 ? 44.078 72.217 -17.126 1.00 11.76 ? 427 ARG A NH2 1 ATOM 3417 N N . MET A 1 428 ? 42.396 72.540 -10.252 1.00 7.31 ? 428 MET A N 1 ATOM 3418 C CA . MET A 1 428 ? 43.782 72.597 -9.753 1.00 7.17 ? 428 MET A CA 1 ATOM 3419 C C . MET A 1 428 ? 44.266 71.196 -9.334 1.00 6.75 ? 428 MET A C 1 ATOM 3420 O O . MET A 1 428 ? 45.436 70.857 -9.555 1.00 7.41 ? 428 MET A O 1 ATOM 3421 C CB . MET A 1 428 ? 43.829 73.558 -8.577 1.00 9.07 ? 428 MET A CB 1 ATOM 3422 C CG . MET A 1 428 ? 45.266 73.950 -8.210 1.00 7.60 ? 428 MET A CG 1 ATOM 3423 S SD . MET A 1 428 ? 45.175 75.273 -6.947 1.00 10.52 ? 428 MET A SD 1 ATOM 3424 C CE . MET A 1 428 ? 46.888 75.787 -6.870 1.00 10.67 ? 428 MET A CE 1 ATOM 3425 N N . ASP A 1 429 ? 43.375 70.385 -8.741 1.00 7.85 ? 429 ASP A N 1 ATOM 3426 C CA . ASP A 1 429 ? 43.708 69.011 -8.361 1.00 7.48 ? 429 ASP A CA 1 ATOM 3427 C C . ASP A 1 429 ? 44.285 68.208 -9.534 1.00 7.33 ? 429 ASP A C 1 ATOM 3428 O O . ASP A 1 429 ? 45.308 67.522 -9.386 1.00 7.04 ? 429 ASP A O 1 ATOM 3429 C CB . ASP A 1 429 ? 42.445 68.300 -7.837 1.00 7.50 ? 429 ASP A CB 1 ATOM 3430 C CG . ASP A 1 429 ? 42.712 66.839 -7.530 1.00 6.60 ? 429 ASP A CG 1 ATOM 3431 O OD1 . ASP A 1 429 ? 42.406 65.971 -8.377 1.00 7.87 ? 429 ASP A OD1 1 ATOM 3432 O OD2 . ASP A 1 429 ? 43.228 66.601 -6.408 1.00 8.29 ? 429 ASP A OD2 1 ATOM 3433 N N . ARG A 1 430 ? 43.617 68.319 -10.690 1.00 6.31 ? 430 ARG A N 1 ATOM 3434 C CA . ARG A 1 430 ? 44.054 67.562 -11.840 1.00 6.72 ? 430 ARG A CA 1 ATOM 3435 C C . ARG A 1 430 ? 45.367 68.095 -12.403 1.00 6.43 ? 430 ARG A C 1 ATOM 3436 O O . ARG A 1 430 ? 46.213 67.312 -12.906 1.00 7.27 ? 430 ARG A O 1 ATOM 3437 C CB . ARG A 1 430 ? 42.990 67.581 -12.946 1.00 6.81 ? 430 ARG A CB 1 ATOM 3438 C CG . ARG A 1 430 ? 41.762 66.857 -12.548 1.00 7.49 ? 430 ARG A CG 1 ATOM 3439 C CD . ARG A 1 430 ? 41.985 65.394 -12.068 1.00 6.76 ? 430 ARG A CD 1 ATOM 3440 N NE . ARG A 1 430 ? 40.734 64.613 -12.088 1.00 7.95 ? 430 ARG A NE 1 ATOM 3441 C CZ . ARG A 1 430 ? 40.042 64.280 -11.005 1.00 6.90 ? 430 ARG A CZ 1 ATOM 3442 N NH1 . ARG A 1 430 ? 40.438 64.612 -9.774 1.00 7.10 ? 430 ARG A NH1 1 ATOM 3443 N NH2 . ARG A 1 430 ? 38.903 63.581 -11.143 1.00 8.04 ? 430 ARG A NH2 1 ATOM 3444 N N . VAL A 1 431 ? 45.572 69.407 -12.353 1.00 6.82 ? 431 VAL A N 1 ATOM 3445 C CA . VAL A 1 431 ? 46.862 69.984 -12.812 1.00 7.11 ? 431 VAL A CA 1 ATOM 3446 C C . VAL A 1 431 ? 47.995 69.465 -11.880 1.00 8.31 ? 431 VAL A C 1 ATOM 3447 O O . VAL A 1 431 ? 49.022 68.974 -12.358 1.00 7.38 ? 431 VAL A O 1 ATOM 3448 C CB . VAL A 1 431 ? 46.748 71.515 -12.780 1.00 6.27 ? 431 VAL A CB 1 ATOM 3449 C CG1 . VAL A 1 431 ? 48.109 72.126 -13.104 1.00 9.22 ? 431 VAL A CG1 1 ATOM 3450 C CG2 . VAL A 1 431 ? 45.715 71.970 -13.839 1.00 9.11 ? 431 VAL A CG2 1 ATOM 3451 N N . LEU A 1 432 ? 47.800 69.595 -10.576 1.00 6.45 ? 432 LEU A N 1 ATOM 3452 C CA . LEU A 1 432 ? 48.822 69.135 -9.643 1.00 6.48 ? 432 LEU A CA 1 ATOM 3453 C C . LEU A 1 432 ? 49.039 67.624 -9.745 1.00 6.79 ? 432 LEU A C 1 ATOM 3454 O O . LEU A 1 432 ? 50.190 67.164 -9.634 1.00 7.36 ? 432 LEU A O 1 ATOM 3455 C CB . LEU A 1 432 ? 48.502 69.607 -8.224 1.00 7.40 ? 432 LEU A CB 1 ATOM 3456 C CG . LEU A 1 432 ? 49.500 69.206 -7.157 1.00 7.71 ? 432 LEU A CG 1 ATOM 3457 C CD1 . LEU A 1 432 ? 50.933 69.738 -7.449 1.00 8.08 ? 432 LEU A CD1 1 ATOM 3458 C CD2 . LEU A 1 432 ? 49.054 69.840 -5.817 1.00 8.83 ? 432 LEU A CD2 1 ATOM 3459 N N . MET A 1 433 ? 47.985 66.851 -9.981 1.00 6.03 ? 433 MET A N 1 ATOM 3460 C CA . MET A 1 433 ? 48.144 65.411 -10.162 1.00 6.93 ? 433 MET A CA 1 ATOM 3461 C C . MET A 1 433 ? 49.193 65.116 -11.215 1.00 6.84 ? 433 MET A C 1 ATOM 3462 O O . MET A 1 433 ? 50.065 64.266 -11.028 1.00 6.35 ? 433 MET A O 1 ATOM 3463 C CB . MET A 1 433 ? 46.795 64.808 -10.665 1.00 6.87 ? 433 MET A CB 1 ATOM 3464 C CG . MET A 1 433 ? 46.891 63.324 -10.937 1.00 6.97 ? 433 MET A CG 1 ATOM 3465 S SD . MET A 1 433 ? 45.323 62.660 -11.621 1.00 9.57 ? 433 MET A SD 1 ATOM 3466 C CE . MET A 1 433 ? 45.391 63.362 -13.261 1.00 12.12 ? 433 MET A CE 1 ATOM 3467 N N . HIS A 1 434 ? 49.079 65.818 -12.343 1.00 6.20 ? 434 HIS A N 1 ATOM 3468 C CA . HIS A 1 434 ? 49.991 65.585 -13.467 1.00 6.86 ? 434 HIS A CA 1 ATOM 3469 C C . HIS A 1 434 ? 51.396 66.098 -13.132 1.00 6.48 ? 434 HIS A C 1 ATOM 3470 O O . HIS A 1 434 ? 52.388 65.446 -13.504 1.00 7.56 ? 434 HIS A O 1 ATOM 3471 C CB . HIS A 1 434 ? 49.448 66.295 -14.737 1.00 7.58 ? 434 HIS A CB 1 ATOM 3472 C CG . HIS A 1 434 ? 50.442 66.244 -15.848 1.00 6.65 ? 434 HIS A CG 1 ATOM 3473 N ND1 . HIS A 1 434 ? 51.264 67.285 -16.248 1.00 11.72 ? 434 HIS A ND1 1 ATOM 3474 C CD2 . HIS A 1 434 ? 50.821 65.156 -16.542 1.00 5.83 ? 434 HIS A CD2 1 ATOM 3475 C CE1 . HIS A 1 434 ? 52.117 66.823 -17.174 1.00 6.24 ? 434 HIS A CE1 1 ATOM 3476 N NE2 . HIS A 1 434 ? 51.865 65.541 -17.350 1.00 11.79 ? 434 HIS A NE2 1 ATOM 3477 N N A TYR A 1 435 ? 51.500 67.275 -12.509 0.50 4.56 ? 435 TYR A N 1 ATOM 3478 N N B TYR A 1 435 ? 51.500 67.275 -12.509 0.50 9.73 ? 435 TYR A N 1 ATOM 3479 C CA A TYR A 1 435 ? 52.832 67.818 -12.194 0.50 3.65 ? 435 TYR A CA 1 ATOM 3480 C CA B TYR A 1 435 ? 52.832 67.818 -12.194 0.50 13.09 ? 435 TYR A CA 1 ATOM 3481 C C A TYR A 1 435 ? 53.563 66.933 -11.185 0.50 1.99 ? 435 TYR A C 1 ATOM 3482 C C B TYR A 1 435 ? 53.426 67.139 -10.960 0.50 14.79 ? 435 TYR A C 1 ATOM 3483 O O A TYR A 1 435 ? 54.793 66.796 -11.276 0.50 1.00 ? 435 TYR A O 1 ATOM 3484 O O B TYR A 1 435 ? 54.656 67.141 -10.798 0.50 20.20 ? 435 TYR A O 1 ATOM 3485 C CB A TYR A 1 435 ? 52.748 69.238 -11.616 0.50 5.49 ? 435 TYR A CB 1 ATOM 3486 C CB B TYR A 1 435 ? 52.786 69.331 -11.935 0.50 16.41 ? 435 TYR A CB 1 ATOM 3487 C CG A TYR A 1 435 ? 52.591 70.414 -12.540 0.50 7.55 ? 435 TYR A CG 1 ATOM 3488 C CG B TYR A 1 435 ? 52.722 70.287 -13.094 0.50 17.49 ? 435 TYR A CG 1 ATOM 3489 C CD1 A TYR A 1 435 ? 51.630 70.475 -13.542 0.50 4.95 ? 435 TYR A CD1 1 ATOM 3490 C CD1 B TYR A 1 435 ? 53.584 70.226 -14.183 0.50 23.46 ? 435 TYR A CD1 1 ATOM 3491 C CD2 A TYR A 1 435 ? 53.368 71.551 -12.310 0.50 10.90 ? 435 TYR A CD2 1 ATOM 3492 C CD2 B TYR A 1 435 ? 51.675 71.209 -13.141 0.50 22.27 ? 435 TYR A CD2 1 ATOM 3493 C CE1 A TYR A 1 435 ? 51.436 71.578 -14.363 0.50 5.56 ? 435 TYR A CE1 1 ATOM 3494 C CE1 B TYR A 1 435 ? 53.499 71.064 -15.286 0.50 25.77 ? 435 TYR A CE1 1 ATOM 3495 C CE2 A TYR A 1 435 ? 53.175 72.707 -13.088 0.50 14.08 ? 435 TYR A CE2 1 ATOM 3496 C CE2 B TYR A 1 435 ? 51.524 72.048 -14.260 0.50 25.98 ? 435 TYR A CE2 1 ATOM 3497 C CZ A TYR A 1 435 ? 52.208 72.682 -14.113 0.50 10.68 ? 435 TYR A CZ 1 ATOM 3498 C CZ B TYR A 1 435 ? 52.460 71.957 -15.309 0.50 25.81 ? 435 TYR A CZ 1 ATOM 3499 O OH A TYR A 1 435 ? 51.994 73.819 -14.873 0.50 14.56 ? 435 TYR A OH 1 ATOM 3500 O OH B TYR A 1 435 ? 52.311 72.763 -16.425 0.50 22.69 ? 435 TYR A OH 1 ATOM 3501 N N . VAL A 1 436 ? 52.848 66.304 -10.243 1.00 6.52 ? 436 VAL A N 1 ATOM 3502 C CA . VAL A 1 436 ? 53.519 65.398 -9.314 1.00 6.53 ? 436 VAL A CA 1 ATOM 3503 C C . VAL A 1 436 ? 54.040 64.198 -10.106 1.00 7.24 ? 436 VAL A C 1 ATOM 3504 O O . VAL A 1 436 ? 55.201 63.744 -9.936 1.00 7.08 ? 436 VAL A O 1 ATOM 3505 C CB . VAL A 1 436 ? 52.539 64.969 -8.181 1.00 6.62 ? 436 VAL A CB 1 ATOM 3506 C CG1 . VAL A 1 436 ? 53.051 63.714 -7.410 1.00 8.06 ? 436 VAL A CG1 1 ATOM 3507 C CG2 . VAL A 1 436 ? 52.355 66.135 -7.173 1.00 7.59 ? 436 VAL A CG2 1 ATOM 3508 N N . ARG A 1 437 ? 53.199 63.603 -10.960 1.00 6.81 ? 437 ARG A N 1 ATOM 3509 C CA . ARG A 1 437 ? 53.669 62.472 -11.753 1.00 6.77 ? 437 ARG A CA 1 ATOM 3510 C C . ARG A 1 437 ? 54.884 62.853 -12.570 1.00 6.87 ? 437 ARG A C 1 ATOM 3511 O O . ARG A 1 437 ? 55.880 62.091 -12.639 1.00 7.81 ? 437 ARG A O 1 ATOM 3512 C CB . ARG A 1 437 ? 52.568 61.966 -12.697 1.00 7.91 ? 437 ARG A CB 1 ATOM 3513 C CG . ARG A 1 437 ? 53.077 60.985 -13.751 1.00 7.01 ? 437 ARG A CG 1 ATOM 3514 C CD . ARG A 1 437 ? 51.937 60.523 -14.613 1.00 8.35 ? 437 ARG A CD 1 ATOM 3515 N NE . ARG A 1 437 ? 52.448 59.768 -15.773 1.00 8.06 ? 437 ARG A NE 1 ATOM 3516 C CZ . ARG A 1 437 ? 51.696 58.946 -16.507 1.00 8.26 ? 437 ARG A CZ 1 ATOM 3517 N NH1 . ARG A 1 437 ? 50.427 58.734 -16.205 1.00 9.54 ? 437 ARG A NH1 1 ATOM 3518 N NH2 . ARG A 1 437 ? 52.225 58.409 -17.598 1.00 9.23 ? 437 ARG A NH2 1 ATOM 3519 N N . ALA A 1 438 ? 54.820 63.993 -13.267 1.00 6.19 ? 438 ALA A N 1 ATOM 3520 C CA . ALA A 1 438 ? 55.926 64.383 -14.151 1.00 7.10 ? 438 ALA A CA 1 ATOM 3521 C C . ALA A 1 438 ? 57.207 64.687 -13.343 1.00 6.74 ? 438 ALA A C 1 ATOM 3522 O O . ALA A 1 438 ? 58.316 64.318 -13.806 1.00 7.92 ? 438 ALA A O 1 ATOM 3523 C CB . ALA A 1 438 ? 55.535 65.612 -14.983 1.00 7.82 ? 438 ALA A CB 1 ATOM 3524 N N . ALA A 1 439 ? 57.083 65.350 -12.176 1.00 7.23 ? 439 ALA A N 1 ATOM 3525 C CA . ALA A 1 439 ? 58.264 65.628 -11.367 1.00 7.25 ? 439 ALA A CA 1 ATOM 3526 C C . ALA A 1 439 ? 58.903 64.349 -10.827 1.00 7.61 ? 439 ALA A C 1 ATOM 3527 O O . ALA A 1 439 ? 60.136 64.209 -10.816 1.00 8.38 ? 439 ALA A O 1 ATOM 3528 C CB . ALA A 1 439 ? 57.912 66.557 -10.247 1.00 8.07 ? 439 ALA A CB 1 ATOM 3529 N N . GLU A 1 440 ? 58.086 63.421 -10.342 1.00 6.61 ? 440 GLU A N 1 ATOM 3530 C CA . GLU A 1 440 ? 58.631 62.166 -9.822 1.00 7.42 ? 440 GLU A CA 1 ATOM 3531 C C . GLU A 1 440 ? 59.277 61.372 -10.963 1.00 7.36 ? 440 GLU A C 1 ATOM 3532 O O . GLU A 1 440 ? 60.337 60.735 -10.778 1.00 8.96 ? 440 GLU A O 1 ATOM 3533 C CB . GLU A 1 440 ? 57.544 61.315 -9.123 1.00 7.83 ? 440 GLU A CB 1 ATOM 3534 C CG . GLU A 1 440 ? 57.003 61.986 -7.857 1.00 8.42 ? 440 GLU A CG 1 ATOM 3535 C CD . GLU A 1 440 ? 56.331 60.985 -6.932 1.00 11.79 ? 440 GLU A CD 1 ATOM 3536 O OE1 . GLU A 1 440 ? 55.229 60.475 -7.206 1.00 11.13 ? 440 GLU A OE1 1 ATOM 3537 O OE2 . GLU A 1 440 ? 56.971 60.638 -5.918 1.00 12.07 ? 440 GLU A OE2 1 ATOM 3538 N N . MET A 1 441 ? 58.653 61.329 -12.145 1.00 7.10 ? 441 MET A N 1 ATOM 3539 C CA . MET A 1 441 ? 59.213 60.564 -13.263 1.00 7.16 ? 441 MET A CA 1 ATOM 3540 C C . MET A 1 441 ? 60.497 61.203 -13.805 1.00 8.01 ? 441 MET A C 1 ATOM 3541 O O . MET A 1 441 ? 61.545 60.493 -13.937 1.00 8.76 ? 441 MET A O 1 ATOM 3542 C CB . MET A 1 441 ? 58.157 60.458 -14.388 1.00 7.34 ? 441 MET A CB 1 ATOM 3543 C CG . MET A 1 441 ? 58.674 59.699 -15.597 1.00 7.60 ? 441 MET A CG 1 ATOM 3544 S SD . MET A 1 441 ? 57.426 59.447 -16.868 1.00 8.61 ? 441 MET A SD 1 ATOM 3545 C CE . MET A 1 441 ? 56.277 58.263 -16.032 1.00 9.65 ? 441 MET A CE 1 ATOM 3546 N N . LEU A 1 442 ? 60.494 62.503 -14.063 1.00 6.86 ? 442 LEU A N 1 ATOM 3547 C CA . LEU A 1 442 ? 61.713 63.149 -14.603 1.00 7.80 ? 442 LEU A CA 1 ATOM 3548 C C . LEU A 1 442 ? 62.899 63.039 -13.689 1.00 8.73 ? 442 LEU A C 1 ATOM 3549 O O . LEU A 1 442 ? 64.043 62.866 -14.195 1.00 9.38 ? 442 LEU A O 1 ATOM 3550 C CB . LEU A 1 442 ? 61.433 64.632 -14.914 1.00 8.30 ? 442 LEU A CB 1 ATOM 3551 C CG . LEU A 1 442 ? 60.741 64.872 -16.275 1.00 7.06 ? 442 LEU A CG 1 ATOM 3552 C CD1 . LEU A 1 442 ? 60.194 66.280 -16.345 1.00 9.94 ? 442 LEU A CD1 1 ATOM 3553 C CD2 . LEU A 1 442 ? 61.814 64.698 -17.415 1.00 10.44 ? 442 LEU A CD2 1 ATOM 3554 N N . SER A 1 443 ? 62.678 63.118 -12.377 1.00 7.41 ? 443 SER A N 1 ATOM 3555 C CA . SER A 1 443 ? 63.775 63.074 -11.440 1.00 8.33 ? 443 SER A CA 1 ATOM 3556 C C . SER A 1 443 ? 64.165 61.646 -11.088 1.00 8.65 ? 443 SER A C 1 ATOM 3557 O O . SER A 1 443 ? 65.288 61.474 -10.552 1.00 9.76 ? 443 SER A O 1 ATOM 3558 C CB . SER A 1 443 ? 63.510 63.905 -10.185 1.00 8.50 ? 443 SER A CB 1 ATOM 3559 O OG . SER A 1 443 ? 62.419 63.345 -9.433 1.00 9.21 ? 443 SER A OG 1 ATOM 3560 N N . ALA A 1 444 ? 63.370 60.649 -11.406 1.00 7.50 ? 444 ALA A N 1 ATOM 3561 C CA . ALA A 1 444 ? 63.666 59.256 -11.073 1.00 8.48 ? 444 ALA A CA 1 ATOM 3562 C C . ALA A 1 444 ? 64.826 58.726 -11.881 1.00 9.37 ? 444 ALA A C 1 ATOM 3563 O O . ALA A 1 444 ? 65.469 57.742 -11.445 1.00 10.44 ? 444 ALA A O 1 ATOM 3564 C CB . ALA A 1 444 ? 62.461 58.360 -11.345 1.00 10.06 ? 444 ALA A CB 1 ATOM 3565 N N . TRP A 1 445 ? 65.085 59.256 -13.071 1.00 9.35 ? 445 TRP A N 1 ATOM 3566 C CA . TRP A 1 445 ? 66.156 58.728 -13.935 1.00 10.89 ? 445 TRP A CA 1 ATOM 3567 C C . TRP A 1 445 ? 67.535 58.803 -13.313 1.00 11.07 ? 445 TRP A C 1 ATOM 3568 O O . TRP A 1 445 ? 68.407 58.007 -13.702 1.00 13.34 ? 445 TRP A O 1 ATOM 3569 C CB . TRP A 1 445 ? 66.159 59.481 -15.264 1.00 10.49 ? 445 TRP A CB 1 ATOM 3570 C CG . TRP A 1 445 ? 64.870 59.318 -16.037 1.00 9.21 ? 445 TRP A CG 1 ATOM 3571 C CD1 . TRP A 1 445 ? 63.884 60.289 -16.194 1.00 9.42 ? 445 TRP A CD1 1 ATOM 3572 C CD2 . TRP A 1 445 ? 64.389 58.136 -16.716 1.00 8.84 ? 445 TRP A CD2 1 ATOM 3573 N NE1 . TRP A 1 445 ? 62.853 59.752 -16.905 1.00 9.49 ? 445 TRP A NE1 1 ATOM 3574 C CE2 . TRP A 1 445 ? 63.126 58.440 -17.251 1.00 8.12 ? 445 TRP A CE2 1 ATOM 3575 C CE3 . TRP A 1 445 ? 64.931 56.846 -16.931 1.00 9.95 ? 445 TRP A CE3 1 ATOM 3576 C CZ2 . TRP A 1 445 ? 62.387 57.533 -17.978 1.00 8.85 ? 445 TRP A CZ2 1 ATOM 3577 C CZ3 . TRP A 1 445 ? 64.196 55.945 -17.654 1.00 10.40 ? 445 TRP A CZ3 1 ATOM 3578 C CH2 . TRP A 1 445 ? 62.923 56.274 -18.177 1.00 9.15 ? 445 TRP A CH2 1 ATOM 3579 N N . HIS A 1 446 ? 67.769 59.756 -12.436 1.00 11.17 ? 446 HIS A N 1 ATOM 3580 C CA . HIS A 1 446 ? 69.072 59.871 -11.799 1.00 12.75 ? 446 HIS A CA 1 ATOM 3581 C C . HIS A 1 446 ? 68.914 59.760 -10.293 1.00 11.59 ? 446 HIS A C 1 ATOM 3582 O O . HIS A 1 446 ? 67.863 59.962 -9.700 1.00 11.64 ? 446 HIS A O 1 ATOM 3583 C CB . HIS A 1 446 ? 69.658 61.268 -12.018 1.00 13.06 ? 446 HIS A CB 1 ATOM 3584 C CG . HIS A 1 446 ? 70.045 61.556 -13.431 1.00 14.80 ? 446 HIS A CG 1 ATOM 3585 N ND1 . HIS A 1 446 ? 69.252 62.299 -14.288 1.00 17.71 ? 446 HIS A ND1 1 ATOM 3586 C CD2 . HIS A 1 446 ? 71.161 61.229 -14.132 1.00 22.00 ? 446 HIS A CD2 1 ATOM 3587 C CE1 . HIS A 1 446 ? 69.862 62.423 -15.452 1.00 24.01 ? 446 HIS A CE1 1 ATOM 3588 N NE2 . HIS A 1 446 ? 71.018 61.786 -15.385 1.00 19.48 ? 446 HIS A NE2 1 ATOM 3589 N N . SER A 1 447 ? 70.058 59.489 -9.653 1.00 12.18 ? 447 SER A N 1 ATOM 3590 C CA . SER A 1 447 ? 70.209 59.582 -8.224 1.00 12.18 ? 447 SER A CA 1 ATOM 3591 C C . SER A 1 447 ? 70.666 61.072 -7.970 1.00 13.12 ? 447 SER A C 1 ATOM 3592 O O . SER A 1 447 ? 71.499 61.594 -8.749 1.00 15.73 ? 447 SER A O 1 ATOM 3593 C CB . SER A 1 447 ? 71.297 58.602 -7.843 1.00 16.93 ? 447 SER A CB 1 ATOM 3594 O OG . SER A 1 447 ? 71.280 58.535 -6.454 1.00 23.12 ? 447 SER A OG 1 ATOM 3595 N N . TRP A 1 448 ? 70.151 61.757 -6.957 1.00 11.35 ? 448 TRP A N 1 ATOM 3596 C CA . TRP A 1 448 ? 70.497 63.152 -6.728 1.00 12.41 ? 448 TRP A CA 1 ATOM 3597 C C . TRP A 1 448 ? 71.192 63.350 -5.403 1.00 14.64 ? 448 TRP A C 1 ATOM 3598 O O . TRP A 1 448 ? 70.845 62.733 -4.410 1.00 14.34 ? 448 TRP A O 1 ATOM 3599 C CB . TRP A 1 448 ? 69.231 64.069 -6.744 1.00 12.81 ? 448 TRP A CB 1 ATOM 3600 C CG . TRP A 1 448 ? 68.577 64.079 -8.111 1.00 11.17 ? 448 TRP A CG 1 ATOM 3601 C CD1 . TRP A 1 448 ? 67.716 63.150 -8.615 1.00 11.88 ? 448 TRP A CD1 1 ATOM 3602 C CD2 . TRP A 1 448 ? 68.745 65.073 -9.124 1.00 9.83 ? 448 TRP A CD2 1 ATOM 3603 N NE1 . TRP A 1 448 ? 67.312 63.500 -9.873 1.00 10.95 ? 448 TRP A NE1 1 ATOM 3604 C CE2 . TRP A 1 448 ? 67.928 64.680 -10.217 1.00 10.34 ? 448 TRP A CE2 1 ATOM 3605 C CE3 . TRP A 1 448 ? 69.506 66.265 -9.213 1.00 11.85 ? 448 TRP A CE3 1 ATOM 3606 C CZ2 . TRP A 1 448 ? 67.830 65.437 -11.381 1.00 12.24 ? 448 TRP A CZ2 1 ATOM 3607 C CZ3 . TRP A 1 448 ? 69.408 67.024 -10.375 1.00 11.80 ? 448 TRP A CZ3 1 ATOM 3608 C CH2 . TRP A 1 448 ? 68.564 66.590 -11.440 1.00 11.57 ? 448 TRP A CH2 1 ATOM 3609 N N . ASP A 1 449 ? 72.160 64.265 -5.390 1.00 15.83 ? 449 ASP A N 1 ATOM 3610 C CA . ASP A 1 449 ? 72.848 64.609 -4.166 1.00 18.61 ? 449 ASP A CA 1 ATOM 3611 C C . ASP A 1 449 ? 71.820 65.251 -3.238 1.00 17.38 ? 449 ASP A C 1 ATOM 3612 O O . ASP A 1 449 ? 70.910 65.937 -3.697 1.00 16.67 ? 449 ASP A O 1 ATOM 3613 C CB . ASP A 1 449 ? 73.975 65.600 -4.491 1.00 22.65 ? 449 ASP A CB 1 ATOM 3614 C CG . ASP A 1 449 ? 74.778 65.970 -3.254 1.00 28.03 ? 449 ASP A CG 1 ATOM 3615 O OD1 . ASP A 1 449 ? 74.515 67.036 -2.670 1.00 29.28 ? 449 ASP A OD1 1 ATOM 3616 O OD2 . ASP A 1 449 ? 75.647 65.152 -2.853 1.00 36.22 ? 449 ASP A OD2 1 ATOM 3617 N N . GLY A 1 450 ? 71.961 65.060 -1.926 1.00 17.36 ? 450 GLY A N 1 ATOM 3618 C CA . GLY A 1 450 ? 71.034 65.654 -0.978 1.00 18.19 ? 450 GLY A CA 1 ATOM 3619 C C . GLY A 1 450 ? 70.958 67.161 -1.091 1.00 19.76 ? 450 GLY A C 1 ATOM 3620 O O . GLY A 1 450 ? 69.926 67.749 -0.764 1.00 19.68 ? 450 GLY A O 1 ATOM 3621 N N A MET A 1 451 ? 72.040 67.816 -1.523 0.50 18.63 ? 451 MET A N 1 ATOM 3622 N N B MET A 1 451 ? 72.040 67.816 -1.523 0.50 18.57 ? 451 MET A N 1 ATOM 3623 C CA A MET A 1 451 ? 72.003 69.265 -1.635 0.50 20.40 ? 451 MET A CA 1 ATOM 3624 C CA B MET A 1 451 ? 72.003 69.265 -1.635 0.50 20.26 ? 451 MET A CA 1 ATOM 3625 C C A MET A 1 451 ? 71.037 69.774 -2.699 0.50 17.72 ? 451 MET A C 1 ATOM 3626 C C B MET A 1 451 ? 71.037 69.774 -2.699 0.50 17.67 ? 451 MET A C 1 ATOM 3627 O O A MET A 1 451 ? 70.707 70.947 -2.714 0.50 19.13 ? 451 MET A O 1 ATOM 3628 O O B MET A 1 451 ? 70.707 70.947 -2.714 0.50 19.18 ? 451 MET A O 1 ATOM 3629 C CB A MET A 1 451 ? 73.407 69.828 -1.949 0.50 24.64 ? 451 MET A CB 1 ATOM 3630 C CB B MET A 1 451 ? 73.407 69.828 -1.949 0.50 24.14 ? 451 MET A CB 1 ATOM 3631 C CG A MET A 1 451 ? 74.416 69.621 -0.804 0.50 31.09 ? 451 MET A CG 1 ATOM 3632 C CG B MET A 1 451 ? 74.402 69.665 -0.785 0.50 29.98 ? 451 MET A CG 1 ATOM 3633 S SD A MET A 1 451 ? 73.967 70.508 0.779 0.50 39.28 ? 451 MET A SD 1 ATOM 3634 S SD B MET A 1 451 ? 75.986 70.636 -0.994 0.50 38.78 ? 451 MET A SD 1 ATOM 3635 C CE A MET A 1 451 ? 73.204 69.080 1.820 0.50 37.78 ? 451 MET A CE 1 ATOM 3636 C CE B MET A 1 451 ? 76.064 70.844 -2.906 0.50 37.30 ? 451 MET A CE 1 ATOM 3637 N N . ALA A 1 452 ? 70.609 68.900 -3.613 1.00 14.76 ? 452 ALA A N 1 ATOM 3638 C CA . ALA A 1 452 ? 69.677 69.294 -4.674 1.00 15.12 ? 452 ALA A CA 1 ATOM 3639 C C . ALA A 1 452 ? 68.258 69.402 -4.112 1.00 13.04 ? 452 ALA A C 1 ATOM 3640 O O . ALA A 1 452 ? 67.400 69.975 -4.784 1.00 15.80 ? 452 ALA A O 1 ATOM 3641 C CB . ALA A 1 452 ? 69.719 68.284 -5.787 1.00 15.30 ? 452 ALA A CB 1 ATOM 3642 N N . ARG A 1 453 ? 68.004 68.852 -2.923 1.00 12.65 ? 453 ARG A N 1 ATOM 3643 C CA . ARG A 1 453 ? 66.683 68.954 -2.272 1.00 14.50 ? 453 ARG A CA 1 ATOM 3644 C C . ARG A 1 453 ? 65.562 68.377 -3.105 1.00 13.22 ? 453 ARG A C 1 ATOM 3645 O O . ARG A 1 453 ? 64.419 68.843 -2.988 1.00 15.20 ? 453 ARG A O 1 ATOM 3646 C CB . ARG A 1 453 ? 66.391 70.423 -1.911 1.00 16.42 ? 453 ARG A CB 1 ATOM 3647 C CG . ARG A 1 453 ? 67.497 71.041 -1.026 1.00 18.73 ? 453 ARG A CG 1 ATOM 3648 C CD . ARG A 1 453 ? 67.324 72.559 -0.889 1.00 25.88 ? 453 ARG A CD 1 ATOM 3649 N NE . ARG A 1 453 ? 66.159 72.832 -0.067 1.00 24.27 ? 453 ARG A NE 1 ATOM 3650 C CZ . ARG A 1 453 ? 65.670 74.045 0.179 1.00 29.00 ? 453 ARG A CZ 1 ATOM 3651 N NH1 . ARG A 1 453 ? 66.245 75.143 -0.346 1.00 27.42 ? 453 ARG A NH1 1 ATOM 3652 N NH2 . ARG A 1 453 ? 64.608 74.158 0.957 1.00 27.30 ? 453 ARG A NH2 1 ATOM 3653 N N . ILE A 1 454 ? 65.851 67.362 -3.904 1.00 11.39 ? 454 ILE A N 1 ATOM 3654 C CA . ILE A 1 454 ? 64.837 66.776 -4.756 1.00 10.89 ? 454 ILE A CA 1 ATOM 3655 C C . ILE A 1 454 ? 63.844 66.007 -3.886 1.00 11.52 ? 454 ILE A C 1 ATOM 3656 O O . ILE A 1 454 ? 62.615 66.222 -4.010 1.00 10.81 ? 454 ILE A O 1 ATOM 3657 C CB . ILE A 1 454 ? 65.496 65.820 -5.767 1.00 11.02 ? 454 ILE A CB 1 ATOM 3658 C CG1 . ILE A 1 454 ? 66.464 66.580 -6.706 1.00 13.57 ? 454 ILE A CG1 1 ATOM 3659 C CG2 . ILE A 1 454 ? 64.403 65.029 -6.535 1.00 12.67 ? 454 ILE A CG2 1 ATOM 3660 C CD1 . ILE A 1 454 ? 65.788 67.676 -7.566 1.00 14.54 ? 454 ILE A CD1 1 ATOM 3661 N N . GLU A 1 455 ? 64.301 65.152 -2.998 1.00 11.44 ? 455 GLU A N 1 ATOM 3662 C CA . GLU A 1 455 ? 63.384 64.362 -2.170 1.00 11.51 ? 455 GLU A CA 1 ATOM 3663 C C . GLU A 1 455 ? 62.538 65.270 -1.303 1.00 11.05 ? 455 GLU A C 1 ATOM 3664 O O . GLU A 1 455 ? 61.327 65.012 -1.081 1.00 10.67 ? 455 GLU A O 1 ATOM 3665 C CB . GLU A 1 455 ? 64.154 63.377 -1.258 1.00 13.23 ? 455 GLU A CB 1 ATOM 3666 C CG . GLU A 1 455 ? 64.761 62.187 -1.979 1.00 14.26 ? 455 GLU A CG 1 ATOM 3667 C CD . GLU A 1 455 ? 66.159 62.441 -2.644 1.00 13.74 ? 455 GLU A CD 1 ATOM 3668 O OE1 . GLU A 1 455 ? 66.652 63.602 -2.586 1.00 16.61 ? 455 GLU A OE1 1 ATOM 3669 O OE2 . GLU A 1 455 ? 66.694 61.453 -3.175 1.00 14.04 ? 455 GLU A OE2 1 ATOM 3670 N N . GLU A 1 456 ? 63.114 66.341 -0.790 1.00 11.91 ? 456 GLU A N 1 ATOM 3671 C CA . GLU A 1 456 ? 62.392 67.254 0.036 1.00 11.11 ? 456 GLU A CA 1 ATOM 3672 C C . GLU A 1 456 ? 61.258 67.892 -0.743 1.00 10.46 ? 456 GLU A C 1 ATOM 3673 O O . GLU A 1 456 ? 60.109 67.994 -0.251 1.00 10.49 ? 456 GLU A O 1 ATOM 3674 C CB . GLU A 1 456 ? 63.379 68.351 0.544 1.00 15.43 ? 456 GLU A CB 1 ATOM 3675 C CG . GLU A 1 456 ? 62.770 69.458 1.291 1.00 16.78 ? 456 GLU A CG 1 ATOM 3676 C CD . GLU A 1 456 ? 63.725 70.638 1.533 1.00 23.70 ? 456 GLU A CD 1 ATOM 3677 O OE1 . GLU A 1 456 ? 64.935 70.497 1.275 1.00 24.38 ? 456 GLU A OE1 1 ATOM 3678 O OE2 . GLU A 1 456 ? 63.250 71.717 1.982 1.00 25.79 ? 456 GLU A OE2 1 ATOM 3679 N N . ARG A 1 457 ? 61.543 68.376 -1.936 1.00 9.80 ? 457 ARG A N 1 ATOM 3680 C CA . ARG A 1 457 ? 60.463 69.071 -2.698 1.00 10.01 ? 457 ARG A CA 1 ATOM 3681 C C . ARG A 1 457 ? 59.376 68.083 -3.151 1.00 8.44 ? 457 ARG A C 1 ATOM 3682 O O . ARG A 1 457 ? 58.172 68.441 -3.107 1.00 9.36 ? 457 ARG A O 1 ATOM 3683 C CB . ARG A 1 457 ? 61.073 69.837 -3.928 1.00 9.68 ? 457 ARG A CB 1 ATOM 3684 C CG . ARG A 1 457 ? 61.423 71.297 -3.697 1.00 12.86 ? 457 ARG A CG 1 ATOM 3685 C CD . ARG A 1 457 ? 62.312 71.513 -2.560 1.00 16.74 ? 457 ARG A CD 1 ATOM 3686 N NE . ARG A 1 457 ? 62.626 72.951 -2.308 1.00 18.40 ? 457 ARG A NE 1 ATOM 3687 C CZ . ARG A 1 457 ? 63.579 73.686 -2.929 1.00 23.00 ? 457 ARG A CZ 1 ATOM 3688 N NH1 . ARG A 1 457 ? 64.394 73.175 -3.895 1.00 19.16 ? 457 ARG A NH1 1 ATOM 3689 N NH2 . ARG A 1 457 ? 63.721 74.962 -2.538 1.00 22.63 ? 457 ARG A NH2 1 ATOM 3690 N N . LEU A 1 458 ? 59.774 66.879 -3.523 1.00 8.03 ? 458 LEU A N 1 ATOM 3691 C CA . LEU A 1 458 ? 58.759 65.888 -3.958 1.00 8.42 ? 458 LEU A CA 1 ATOM 3692 C C . LEU A 1 458 ? 57.914 65.452 -2.760 1.00 10.71 ? 458 LEU A C 1 ATOM 3693 O O . LEU A 1 458 ? 56.693 65.252 -2.938 1.00 10.52 ? 458 LEU A O 1 ATOM 3694 C CB . LEU A 1 458 ? 59.464 64.696 -4.564 1.00 9.54 ? 458 LEU A CB 1 ATOM 3695 C CG . LEU A 1 458 ? 60.156 65.021 -5.910 1.00 9.16 ? 458 LEU A CG 1 ATOM 3696 C CD1 . LEU A 1 458 ? 60.882 63.749 -6.358 1.00 12.15 ? 458 LEU A CD1 1 ATOM 3697 C CD2 . LEU A 1 458 ? 59.045 65.369 -6.994 1.00 10.97 ? 458 LEU A CD2 1 ATOM 3698 N N . GLU A 1 459 ? 58.500 65.320 -1.558 1.00 9.22 ? 459 GLU A N 1 ATOM 3699 C CA . GLU A 1 459 ? 57.678 64.921 -0.412 1.00 8.93 ? 459 GLU A CA 1 ATOM 3700 C C . GLU A 1 459 ? 56.684 66.037 -0.109 1.00 10.00 ? 459 GLU A C 1 ATOM 3701 O O . GLU A 1 459 ? 55.493 65.759 0.176 1.00 9.19 ? 459 GLU A O 1 ATOM 3702 C CB . GLU A 1 459 ? 58.570 64.665 0.808 1.00 11.37 ? 459 GLU A CB 1 ATOM 3703 C CG . GLU A 1 459 ? 57.773 64.458 2.116 1.00 13.51 ? 459 GLU A CG 1 ATOM 3704 C CD . GLU A 1 459 ? 58.648 63.822 3.162 1.00 16.72 ? 459 GLU A CD 1 ATOM 3705 O OE1 . GLU A 1 459 ? 59.282 64.598 3.875 1.00 20.98 ? 459 GLU A OE1 1 ATOM 3706 O OE2 . GLU A 1 459 ? 58.710 62.568 3.241 1.00 20.42 ? 459 GLU A OE2 1 ATOM 3707 N N . GLN A 1 460 ? 57.099 67.315 -0.174 1.00 8.35 ? 460 GLN A N 1 ATOM 3708 C CA . GLN A 1 460 ? 56.152 68.409 0.055 1.00 9.19 ? 460 GLN A CA 1 ATOM 3709 C C . GLN A 1 460 ? 55.015 68.346 -1.001 1.00 9.81 ? 460 GLN A C 1 ATOM 3710 O O . GLN A 1 460 ? 53.817 68.446 -0.659 1.00 9.97 ? 460 GLN A O 1 ATOM 3711 C CB . GLN A 1 460 ? 56.889 69.744 -0.077 1.00 11.94 ? 460 GLN A CB 1 ATOM 3712 C CG . GLN A 1 460 ? 56.046 70.946 0.087 1.00 17.72 ? 460 GLN A CG 1 ATOM 3713 C CD . GLN A 1 460 ? 56.814 72.238 -0.246 1.00 20.27 ? 460 GLN A CD 1 ATOM 3714 O OE1 . GLN A 1 460 ? 56.328 73.314 0.064 1.00 31.41 ? 460 GLN A OE1 1 ATOM 3715 N NE2 . GLN A 1 460 ? 57.974 72.124 -0.925 1.00 24.74 ? 460 GLN A NE2 1 ATOM 3716 N N . ALA A 1 461 ? 55.376 68.181 -2.276 1.00 8.17 ? 461 ALA A N 1 ATOM 3717 C CA . ALA A 1 461 ? 54.317 68.141 -3.300 1.00 8.44 ? 461 ALA A CA 1 ATOM 3718 C C . ALA A 1 461 ? 53.375 66.964 -3.091 1.00 8.13 ? 461 ALA A C 1 ATOM 3719 O O . ALA A 1 461 ? 52.133 67.166 -3.203 1.00 8.71 ? 461 ALA A O 1 ATOM 3720 C CB . ALA A 1 461 ? 54.968 68.084 -4.666 1.00 9.30 ? 461 ALA A CB 1 ATOM 3721 N N . ARG A 1 462 ? 53.893 65.776 -2.822 1.00 7.65 ? 462 ARG A N 1 ATOM 3722 C CA . ARG A 1 462 ? 53.001 64.637 -2.608 1.00 7.22 ? 462 ARG A CA 1 ATOM 3723 C C . ARG A 1 462 ? 52.094 64.863 -1.416 1.00 8.27 ? 462 ARG A C 1 ATOM 3724 O O . ARG A 1 462 ? 50.903 64.508 -1.463 1.00 8.33 ? 462 ARG A O 1 ATOM 3725 C CB . ARG A 1 462 ? 53.747 63.324 -2.353 1.00 8.31 ? 462 ARG A CB 1 ATOM 3726 C CG . ARG A 1 462 ? 54.531 62.811 -3.567 1.00 7.87 ? 462 ARG A CG 1 ATOM 3727 C CD . ARG A 1 462 ? 54.987 61.360 -3.295 1.00 9.54 ? 462 ARG A CD 1 ATOM 3728 N NE . ARG A 1 462 ? 55.909 61.266 -2.143 1.00 9.10 ? 462 ARG A NE 1 ATOM 3729 C CZ . ARG A 1 462 ? 57.213 61.411 -2.235 1.00 9.84 ? 462 ARG A CZ 1 ATOM 3730 N NH1 . ARG A 1 462 ? 57.800 61.613 -3.402 1.00 11.09 ? 462 ARG A NH1 1 ATOM 3731 N NH2 . ARG A 1 462 ? 57.970 61.415 -1.132 1.00 12.69 ? 462 ARG A NH2 1 ATOM 3732 N N . ARG A 1 463 ? 52.600 65.471 -0.355 1.00 8.21 ? 463 ARG A N 1 ATOM 3733 C CA . ARG A 1 463 ? 51.794 65.641 0.860 1.00 8.27 ? 463 ARG A CA 1 ATOM 3734 C C . ARG A 1 463 ? 50.750 66.694 0.676 1.00 8.19 ? 463 ARG A C 1 ATOM 3735 O O . ARG A 1 463 ? 49.632 66.496 1.205 1.00 9.25 ? 463 ARG A O 1 ATOM 3736 C CB . ARG A 1 463 ? 52.702 65.936 2.067 1.00 8.83 ? 463 ARG A CB 1 ATOM 3737 C CG . ARG A 1 463 ? 53.374 64.642 2.504 1.00 9.42 ? 463 ARG A CG 1 ATOM 3738 C CD . ARG A 1 463 ? 54.430 64.828 3.611 1.00 11.18 ? 463 ARG A CD 1 ATOM 3739 N NE . ARG A 1 463 ? 54.934 63.490 3.959 1.00 13.10 ? 463 ARG A NE 1 ATOM 3740 C CZ . ARG A 1 463 ? 55.693 63.243 5.021 1.00 15.16 ? 463 ARG A CZ 1 ATOM 3741 N NH1 . ARG A 1 463 ? 56.018 64.259 5.783 1.00 15.92 ? 463 ARG A NH1 1 ATOM 3742 N NH2 . ARG A 1 463 ? 56.050 61.978 5.273 1.00 16.54 ? 463 ARG A NH2 1 ATOM 3743 N N . GLU A 1 464 ? 50.993 67.799 -0.034 1.00 7.49 ? 464 GLU A N 1 ATOM 3744 C CA . GLU A 1 464 ? 49.917 68.783 -0.219 1.00 8.66 ? 464 GLU A CA 1 ATOM 3745 C C . GLU A 1 464 ? 48.862 68.263 -1.155 1.00 9.05 ? 464 GLU A C 1 ATOM 3746 O O . GLU A 1 464 ? 47.683 68.528 -0.893 1.00 8.53 ? 464 GLU A O 1 ATOM 3747 C CB . GLU A 1 464 ? 50.427 70.117 -0.762 1.00 10.63 ? 464 GLU A CB 1 ATOM 3748 C CG . GLU A 1 464 ? 51.614 70.773 0.057 1.00 12.39 ? 464 GLU A CG 1 ATOM 3749 C CD . GLU A 1 464 ? 51.299 71.188 1.465 1.00 18.16 ? 464 GLU A CD 1 ATOM 3750 O OE1 . GLU A 1 464 ? 50.304 70.771 2.050 1.00 17.27 ? 464 GLU A OE1 1 ATOM 3751 O OE2 . GLU A 1 464 ? 52.149 71.948 2.007 1.00 22.73 ? 464 GLU A OE2 1 ATOM 3752 N N . LEU A 1 465 ? 49.234 67.532 -2.206 1.00 7.04 ? 465 LEU A N 1 ATOM 3753 C CA . LEU A 1 465 ? 48.198 66.981 -3.110 1.00 7.36 ? 465 LEU A CA 1 ATOM 3754 C C . LEU A 1 465 ? 47.430 65.907 -2.311 1.00 7.05 ? 465 LEU A C 1 ATOM 3755 O O . LEU A 1 465 ? 46.186 65.803 -2.414 1.00 7.57 ? 465 LEU A O 1 ATOM 3756 C CB . LEU A 1 465 ? 48.864 66.334 -4.340 1.00 7.87 ? 465 LEU A CB 1 ATOM 3757 C CG . LEU A 1 465 ? 47.862 65.679 -5.325 1.00 7.29 ? 465 LEU A CG 1 ATOM 3758 C CD1 . LEU A 1 465 ? 46.736 66.655 -5.772 1.00 9.03 ? 465 LEU A CD1 1 ATOM 3759 C CD2 . LEU A 1 465 ? 48.634 65.150 -6.530 1.00 8.95 ? 465 LEU A CD2 1 ATOM 3760 N N . SER A 1 466 ? 48.120 65.079 -1.520 1.00 6.88 ? 466 SER A N 1 ATOM 3761 C CA . SER A 1 466 ? 47.443 64.077 -0.705 1.00 6.32 ? 466 SER A CA 1 ATOM 3762 C C . SER A 1 466 ? 46.444 64.674 0.272 1.00 6.82 ? 466 SER A C 1 ATOM 3763 O O . SER A 1 466 ? 45.308 64.149 0.422 1.00 7.37 ? 466 SER A O 1 ATOM 3764 C CB . SER A 1 466 ? 48.459 63.217 0.040 1.00 7.18 ? 466 SER A CB 1 ATOM 3765 O OG . SER A 1 466 ? 49.225 62.408 -0.832 1.00 7.59 ? 466 SER A OG 1 ATOM 3766 N N . LEU A 1 467 ? 46.825 65.761 0.934 1.00 6.61 ? 467 LEU A N 1 ATOM 3767 C CA . LEU A 1 467 ? 45.951 66.412 1.886 1.00 7.15 ? 467 LEU A CA 1 ATOM 3768 C C . LEU A 1 467 ? 44.649 66.843 1.183 1.00 7.01 ? 467 LEU A C 1 ATOM 3769 O O . LEU A 1 467 ? 43.564 66.738 1.765 1.00 7.18 ? 467 LEU A O 1 ATOM 3770 C CB . LEU A 1 467 ? 46.686 67.631 2.478 1.00 8.03 ? 467 LEU A CB 1 ATOM 3771 C CG . LEU A 1 467 ? 45.909 68.252 3.628 1.00 12.37 ? 467 LEU A CG 1 ATOM 3772 C CD1 . LEU A 1 467 ? 46.189 67.290 4.918 1.00 16.31 ? 467 LEU A CD1 1 ATOM 3773 C CD2 . LEU A 1 467 ? 46.499 69.692 3.891 1.00 13.60 ? 467 LEU A CD2 1 ATOM 3774 N N . PHE A 1 468 ? 44.759 67.354 -0.038 1.00 6.63 ? 468 PHE A N 1 ATOM 3775 C CA . PHE A 1 468 ? 43.580 67.871 -0.754 1.00 6.92 ? 468 PHE A CA 1 ATOM 3776 C C . PHE A 1 468 ? 42.592 66.782 -1.136 1.00 6.19 ? 468 PHE A C 1 ATOM 3777 O O . PHE A 1 468 ? 41.433 67.075 -1.419 1.00 7.81 ? 468 PHE A O 1 ATOM 3778 C CB . PHE A 1 468 ? 43.998 68.688 -1.969 1.00 7.89 ? 468 PHE A CB 1 ATOM 3779 C CG . PHE A 1 468 ? 42.877 69.518 -2.537 1.00 6.63 ? 468 PHE A CG 1 ATOM 3780 C CD1 . PHE A 1 468 ? 42.234 70.450 -1.740 1.00 8.48 ? 468 PHE A CD1 1 ATOM 3781 C CD2 . PHE A 1 468 ? 42.429 69.354 -3.855 1.00 7.61 ? 468 PHE A CD2 1 ATOM 3782 C CE1 . PHE A 1 468 ? 41.165 71.209 -2.215 1.00 7.56 ? 468 PHE A CE1 1 ATOM 3783 C CE2 . PHE A 1 468 ? 41.352 70.111 -4.329 1.00 7.53 ? 468 PHE A CE2 1 ATOM 3784 C CZ . PHE A 1 468 ? 40.740 71.021 -3.518 1.00 7.19 ? 468 PHE A CZ 1 ATOM 3785 N N . GLN A 1 469 ? 43.010 65.506 -1.114 1.00 6.23 ? 469 GLN A N 1 ATOM 3786 C CA . GLN A 1 469 ? 42.083 64.413 -1.369 1.00 6.47 ? 469 GLN A CA 1 ATOM 3787 C C . GLN A 1 469 ? 41.067 64.256 -0.236 1.00 6.35 ? 469 GLN A C 1 ATOM 3788 O O . GLN A 1 469 ? 40.082 63.507 -0.428 1.00 6.87 ? 469 GLN A O 1 ATOM 3789 C CB . GLN A 1 469 ? 42.807 63.075 -1.561 1.00 6.98 ? 469 GLN A CB 1 ATOM 3790 C CG . GLN A 1 469 ? 43.892 63.134 -2.669 1.00 6.86 ? 469 GLN A CG 1 ATOM 3791 C CD . GLN A 1 469 ? 43.407 63.823 -3.941 1.00 6.38 ? 469 GLN A CD 1 ATOM 3792 O OE1 . GLN A 1 469 ? 44.035 64.852 -4.378 1.00 9.52 ? 469 GLN A OE1 1 ATOM 3793 N NE2 . GLN A 1 469 ? 42.368 63.334 -4.531 1.00 5.57 ? 469 GLN A NE2 1 ATOM 3794 N N . HIS A 1 470 ? 41.296 64.890 0.905 1.00 5.95 ? 470 HIS A N 1 ATOM 3795 C CA . HIS A 1 470 ? 40.355 64.842 2.003 1.00 6.01 ? 470 HIS A CA 1 ATOM 3796 C C . HIS A 1 470 ? 38.920 65.117 1.509 1.00 7.58 ? 470 HIS A C 1 ATOM 3797 O O . HIS A 1 470 ? 38.688 65.879 0.578 1.00 7.55 ? 470 HIS A O 1 ATOM 3798 C CB . HIS A 1 470 ? 40.785 65.905 3.054 1.00 7.02 ? 470 HIS A CB 1 ATOM 3799 C CG . HIS A 1 470 ? 39.788 66.062 4.143 1.00 6.70 ? 470 HIS A CG 1 ATOM 3800 N ND1 . HIS A 1 470 ? 39.309 67.254 4.649 1.00 10.37 ? 470 HIS A ND1 1 ATOM 3801 C CD2 . HIS A 1 470 ? 39.188 65.063 4.838 1.00 6.95 ? 470 HIS A CD2 1 ATOM 3802 C CE1 . HIS A 1 470 ? 38.448 66.961 5.630 1.00 6.66 ? 470 HIS A CE1 1 ATOM 3803 N NE2 . HIS A 1 470 ? 38.371 65.652 5.755 1.00 13.26 ? 470 HIS A NE2 1 ATOM 3804 N N . HIS A 1 471 ? 37.964 64.481 2.207 1.00 7.31 ? 471 HIS A N 1 ATOM 3805 C CA . HIS A 1 471 ? 36.536 64.628 1.898 1.00 7.92 ? 471 HIS A CA 1 ATOM 3806 C C . HIS A 1 471 ? 35.896 65.996 2.250 1.00 7.19 ? 471 HIS A C 1 ATOM 3807 O O . HIS A 1 471 ? 34.714 66.171 2.020 1.00 8.48 ? 471 HIS A O 1 ATOM 3808 C CB . HIS A 1 471 ? 35.713 63.461 2.482 1.00 7.46 ? 471 HIS A CB 1 ATOM 3809 C CG . HIS A 1 471 ? 35.812 63.359 3.978 1.00 7.32 ? 471 HIS A CG 1 ATOM 3810 N ND1 . HIS A 1 471 ? 36.775 62.607 4.656 1.00 8.08 ? 471 HIS A ND1 1 ATOM 3811 C CD2 . HIS A 1 471 ? 35.108 63.999 4.955 1.00 7.14 ? 471 HIS A CD2 1 ATOM 3812 C CE1 . HIS A 1 471 ? 36.624 62.768 5.970 1.00 9.32 ? 471 HIS A CE1 1 ATOM 3813 N NE2 . HIS A 1 471 ? 35.620 63.609 6.183 1.00 6.70 ? 471 HIS A NE2 1 ATOM 3814 N N . ASP A 1 472 ? 36.712 66.992 2.694 1.00 7.93 ? 472 ASP A N 1 ATOM 3815 C CA . ASP A 1 472 ? 36.281 68.397 2.699 1.00 8.09 ? 472 ASP A CA 1 ATOM 3816 C C . ASP A 1 472 ? 37.255 69.249 1.867 1.00 9.28 ? 472 ASP A C 1 ATOM 3817 O O . ASP A 1 472 ? 37.154 70.484 1.889 1.00 9.23 ? 472 ASP A O 1 ATOM 3818 C CB . ASP A 1 472 ? 36.152 68.995 4.118 1.00 8.34 ? 472 ASP A CB 1 ATOM 3819 C CG . ASP A 1 472 ? 35.099 68.283 4.922 1.00 8.00 ? 472 ASP A CG 1 ATOM 3820 O OD1 . ASP A 1 472 ? 33.917 68.307 4.471 1.00 8.64 ? 472 ASP A OD1 1 ATOM 3821 O OD2 . ASP A 1 472 ? 35.459 67.686 5.962 1.00 9.34 ? 472 ASP A OD2 1 ATOM 3822 N N . GLY A 1 473 ? 38.171 68.634 1.113 1.00 7.67 ? 473 GLY A N 1 ATOM 3823 C CA . GLY A 1 473 ? 39.155 69.370 0.292 1.00 7.44 ? 473 GLY A CA 1 ATOM 3824 C C . GLY A 1 473 ? 38.630 69.456 -1.129 1.00 6.92 ? 473 GLY A C 1 ATOM 3825 O O . GLY A 1 473 ? 37.877 70.388 -1.482 1.00 7.39 ? 473 GLY A O 1 ATOM 3826 N N . ILE A 1 474 ? 38.934 68.418 -1.936 1.00 6.60 ? 474 ILE A N 1 ATOM 3827 C CA . ILE A 1 474 ? 38.515 68.422 -3.327 1.00 7.58 ? 474 ILE A CA 1 ATOM 3828 C C . ILE A 1 474 ? 36.980 68.527 -3.461 1.00 7.59 ? 474 ILE A C 1 ATOM 3829 O O . ILE A 1 474 ? 36.495 69.017 -4.487 1.00 8.32 ? 474 ILE A O 1 ATOM 3830 C CB . ILE A 1 474 ? 39.077 67.151 -4.035 1.00 6.18 ? 474 ILE A CB 1 ATOM 3831 C CG1 . ILE A 1 474 ? 38.839 67.239 -5.540 1.00 8.05 ? 474 ILE A CG1 1 ATOM 3832 C CG2 . ILE A 1 474 ? 38.508 65.830 -3.417 1.00 8.07 ? 474 ILE A CG2 1 ATOM 3833 C CD1 . ILE A 1 474 ? 39.579 66.094 -6.319 1.00 9.18 ? 474 ILE A CD1 1 ATOM 3834 N N . THR A 1 475 ? 36.230 68.101 -2.460 1.00 7.24 ? 475 THR A N 1 ATOM 3835 C CA . THR A 1 475 ? 34.770 68.183 -2.479 1.00 7.44 ? 475 THR A CA 1 ATOM 3836 C C . THR A 1 475 ? 34.247 69.629 -2.477 1.00 7.27 ? 475 THR A C 1 ATOM 3837 O O . THR A 1 475 ? 33.062 69.837 -2.825 1.00 8.04 ? 475 THR A O 1 ATOM 3838 C CB . THR A 1 475 ? 34.215 67.529 -1.218 1.00 7.95 ? 475 THR A CB 1 ATOM 3839 O OG1 . THR A 1 475 ? 34.764 68.256 -0.115 1.00 8.12 ? 475 THR A OG1 1 ATOM 3840 C CG2 . THR A 1 475 ? 34.582 66.031 -1.083 1.00 8.74 ? 475 THR A CG2 1 ATOM 3841 N N . GLY A 1 476 ? 35.055 70.620 -2.101 1.00 7.11 ? 476 GLY A N 1 ATOM 3842 C CA . GLY A 1 476 ? 34.527 71.976 -2.070 1.00 7.38 ? 476 GLY A CA 1 ATOM 3843 C C . GLY A 1 476 ? 33.540 72.212 -0.929 1.00 7.91 ? 476 GLY A C 1 ATOM 3844 O O . GLY A 1 476 ? 32.648 73.050 -1.088 1.00 8.72 ? 476 GLY A O 1 ATOM 3845 N N . THR A 1 477 ? 33.691 71.500 0.185 1.00 7.17 ? 477 THR A N 1 ATOM 3846 C CA . THR A 1 477 ? 32.801 71.635 1.302 1.00 8.10 ? 477 THR A CA 1 ATOM 3847 C C . THR A 1 477 ? 33.468 72.256 2.527 1.00 8.51 ? 477 THR A C 1 ATOM 3848 O O . THR A 1 477 ? 32.924 72.120 3.647 1.00 10.80 ? 477 THR A O 1 ATOM 3849 C CB . THR A 1 477 ? 32.143 70.279 1.670 1.00 8.06 ? 477 THR A CB 1 ATOM 3850 O OG1 . THR A 1 477 ? 33.163 69.298 1.930 1.00 8.94 ? 477 THR A OG1 1 ATOM 3851 C CG2 . THR A 1 477 ? 31.290 69.763 0.486 1.00 8.46 ? 477 THR A CG2 1 ATOM 3852 N N . ALA A 1 478 ? 34.569 73.004 2.374 1.00 8.26 ? 478 ALA A N 1 ATOM 3853 C CA . ALA A 1 478 ? 35.217 73.641 3.548 1.00 8.42 ? 478 ALA A CA 1 ATOM 3854 C C . ALA A 1 478 ? 34.897 75.134 3.603 1.00 8.68 ? 478 ALA A C 1 ATOM 3855 O O . ALA A 1 478 ? 34.390 75.744 2.667 1.00 9.36 ? 478 ALA A O 1 ATOM 3856 C CB . ALA A 1 478 ? 36.774 73.431 3.497 1.00 10.18 ? 478 ALA A CB 1 ATOM 3857 N N . LYS A 1 479 ? 35.194 75.740 4.758 1.00 9.21 ? 479 LYS A N 1 ATOM 3858 C CA . LYS A 1 479 ? 34.976 77.202 4.899 1.00 10.56 ? 479 LYS A CA 1 ATOM 3859 C C . LYS A 1 479 ? 35.918 77.936 3.966 1.00 9.49 ? 479 LYS A C 1 ATOM 3860 O O . LYS A 1 479 ? 36.996 77.431 3.600 1.00 9.19 ? 479 LYS A O 1 ATOM 3861 C CB . LYS A 1 479 ? 35.223 77.646 6.353 1.00 11.25 ? 479 LYS A CB 1 ATOM 3862 C CG . LYS A 1 479 ? 34.007 77.312 7.275 1.00 17.96 ? 479 LYS A CG 1 ATOM 3863 C CD . LYS A 1 479 ? 33.848 78.407 8.329 1.00 23.59 ? 479 LYS A CD 1 ATOM 3864 C CE . LYS A 1 479 ? 32.623 78.149 9.231 1.00 22.20 ? 479 LYS A CE 1 ATOM 3865 N NZ . LYS A 1 479 ? 31.295 78.676 8.717 1.00 22.96 ? 479 LYS A NZ 1 ATOM 3866 N N . THR A 1 480 ? 35.535 79.163 3.583 1.00 10.57 ? 480 THR A N 1 ATOM 3867 C CA . THR A 1 480 ? 36.341 79.938 2.668 1.00 10.40 ? 480 THR A CA 1 ATOM 3868 C C . THR A 1 480 ? 37.825 80.036 3.024 1.00 9.86 ? 480 THR A C 1 ATOM 3869 O O . THR A 1 480 ? 38.708 79.826 2.171 1.00 10.65 ? 480 THR A O 1 ATOM 3870 C CB . THR A 1 480 ? 35.767 81.371 2.571 1.00 13.34 ? 480 THR A CB 1 ATOM 3871 O OG1 . THR A 1 480 ? 34.434 81.255 2.072 1.00 17.23 ? 480 THR A OG1 1 ATOM 3872 C CG2 . THR A 1 480 ? 36.600 82.282 1.625 1.00 16.52 ? 480 THR A CG2 1 ATOM 3873 N N . HIS A 1 481 ? 38.166 80.328 4.287 1.00 10.24 ? 481 HIS A N 1 ATOM 3874 C CA . HIS A 1 481 ? 39.593 80.473 4.600 1.00 9.24 ? 481 HIS A CA 1 ATOM 3875 C C . HIS A 1 481 ? 40.340 79.137 4.573 1.00 10.68 ? 481 HIS A C 1 ATOM 3876 O O . HIS A 1 481 ? 41.548 79.101 4.389 1.00 10.72 ? 481 HIS A O 1 ATOM 3877 C CB . HIS A 1 481 ? 39.791 81.179 5.981 1.00 11.02 ? 481 HIS A CB 1 ATOM 3878 C CG . HIS A 1 481 ? 39.660 80.277 7.173 1.00 10.92 ? 481 HIS A CG 1 ATOM 3879 N ND1 . HIS A 1 481 ? 38.447 79.820 7.662 1.00 14.36 ? 481 HIS A ND1 1 ATOM 3880 C CD2 . HIS A 1 481 ? 40.612 79.773 7.997 1.00 11.42 ? 481 HIS A CD2 1 ATOM 3881 C CE1 . HIS A 1 481 ? 38.667 79.087 8.736 1.00 14.01 ? 481 HIS A CE1 1 ATOM 3882 N NE2 . HIS A 1 481 ? 39.971 79.040 8.953 1.00 12.82 ? 481 HIS A NE2 1 ATOM 3883 N N . VAL A 1 482 ? 39.593 78.027 4.707 1.00 10.49 ? 482 VAL A N 1 ATOM 3884 C CA . VAL A 1 482 ? 40.219 76.713 4.606 1.00 9.39 ? 482 VAL A CA 1 ATOM 3885 C C . VAL A 1 482 ? 40.482 76.371 3.144 1.00 8.30 ? 482 VAL A C 1 ATOM 3886 O O . VAL A 1 482 ? 41.549 75.820 2.800 1.00 9.24 ? 482 VAL A O 1 ATOM 3887 C CB . VAL A 1 482 ? 39.296 75.661 5.283 1.00 7.82 ? 482 VAL A CB 1 ATOM 3888 C CG1 . VAL A 1 482 ? 39.949 74.241 5.209 1.00 8.98 ? 482 VAL A CG1 1 ATOM 3889 C CG2 . VAL A 1 482 ? 39.094 76.025 6.786 1.00 10.19 ? 482 VAL A CG2 1 ATOM 3890 N N . VAL A 1 483 ? 39.545 76.711 2.259 1.00 8.01 ? 483 VAL A N 1 ATOM 3891 C CA . VAL A 1 483 ? 39.788 76.556 0.834 1.00 9.21 ? 483 VAL A CA 1 ATOM 3892 C C . VAL A 1 483 ? 41.037 77.335 0.420 1.00 8.56 ? 483 VAL A C 1 ATOM 3893 O O . VAL A 1 483 ? 41.877 76.841 -0.329 1.00 9.20 ? 483 VAL A O 1 ATOM 3894 C CB . VAL A 1 483 ? 38.550 77.082 0.027 1.00 8.04 ? 483 VAL A CB 1 ATOM 3895 C CG1 . VAL A 1 483 ? 38.765 77.054 -1.456 1.00 11.42 ? 483 VAL A CG1 1 ATOM 3896 C CG2 . VAL A 1 483 ? 37.339 76.157 0.328 1.00 10.19 ? 483 VAL A CG2 1 ATOM 3897 N N . VAL A 1 484 ? 41.202 78.555 0.982 1.00 9.41 ? 484 VAL A N 1 ATOM 3898 C CA . VAL A 1 484 ? 42.394 79.359 0.656 1.00 11.64 ? 484 VAL A CA 1 ATOM 3899 C C . VAL A 1 484 ? 43.645 78.651 1.139 1.00 10.29 ? 484 VAL A C 1 ATOM 3900 O O . VAL A 1 484 ? 44.661 78.640 0.409 1.00 9.99 ? 484 VAL A O 1 ATOM 3901 C CB . VAL A 1 484 ? 42.265 80.771 1.272 1.00 11.29 ? 484 VAL A CB 1 ATOM 3902 C CG1 . VAL A 1 484 ? 43.637 81.524 1.136 1.00 13.92 ? 484 VAL A CG1 1 ATOM 3903 C CG2 . VAL A 1 484 ? 41.180 81.558 0.522 1.00 14.61 ? 484 VAL A CG2 1 ATOM 3904 N N . ASP A 1 485 ? 43.603 78.038 2.310 1.00 9.43 ? 485 ASP A N 1 ATOM 3905 C CA . ASP A 1 485 ? 44.754 77.290 2.799 1.00 8.37 ? 485 ASP A CA 1 ATOM 3906 C C . ASP A 1 485 ? 45.115 76.131 1.873 1.00 9.89 ? 485 ASP A C 1 ATOM 3907 O O . ASP A 1 485 ? 46.299 75.897 1.548 1.00 9.49 ? 485 ASP A O 1 ATOM 3908 C CB . ASP A 1 485 ? 44.495 76.766 4.235 1.00 9.52 ? 485 ASP A CB 1 ATOM 3909 C CG . ASP A 1 485 ? 45.731 76.134 4.850 1.00 10.65 ? 485 ASP A CG 1 ATOM 3910 O OD1 . ASP A 1 485 ? 45.751 74.954 5.225 1.00 11.74 ? 485 ASP A OD1 1 ATOM 3911 O OD2 . ASP A 1 485 ? 46.760 76.873 4.946 1.00 16.85 ? 485 ASP A OD2 1 ATOM 3912 N N . TYR A 1 486 ? 44.118 75.354 1.434 1.00 8.74 ? 486 TYR A N 1 ATOM 3913 C CA . TYR A 1 486 ? 44.409 74.272 0.471 1.00 7.56 ? 486 TYR A CA 1 ATOM 3914 C C . TYR A 1 486 ? 44.992 74.808 -0.829 1.00 8.69 ? 486 TYR A C 1 ATOM 3915 O O . TYR A 1 486 ? 45.930 74.206 -1.359 1.00 9.16 ? 486 TYR A O 1 ATOM 3916 C CB . TYR A 1 486 ? 43.132 73.473 0.133 1.00 8.77 ? 486 TYR A CB 1 ATOM 3917 C CG . TYR A 1 486 ? 42.547 72.626 1.265 1.00 8.35 ? 486 TYR A CG 1 ATOM 3918 C CD1 . TYR A 1 486 ? 41.174 72.650 1.495 1.00 8.95 ? 486 TYR A CD1 1 ATOM 3919 C CD2 . TYR A 1 486 ? 43.358 71.777 2.042 1.00 10.84 ? 486 TYR A CD2 1 ATOM 3920 C CE1 . TYR A 1 486 ? 40.591 71.846 2.487 1.00 9.89 ? 486 TYR A CE1 1 ATOM 3921 C CE2 . TYR A 1 486 ? 42.764 70.939 3.052 1.00 10.86 ? 486 TYR A CE2 1 ATOM 3922 C CZ . TYR A 1 486 ? 41.392 71.018 3.226 1.00 8.12 ? 486 TYR A CZ 1 ATOM 3923 O OH . TYR A 1 486 ? 40.781 70.199 4.150 1.00 10.94 ? 486 TYR A OH 1 ATOM 3924 N N . GLU A 1 487 ? 44.461 75.926 -1.318 1.00 8.57 ? 487 GLU A N 1 ATOM 3925 C CA . GLU A 1 487 ? 44.960 76.498 -2.542 1.00 9.61 ? 487 GLU A CA 1 ATOM 3926 C C . GLU A 1 487 ? 46.438 76.925 -2.380 1.00 9.81 ? 487 GLU A C 1 ATOM 3927 O O . GLU A 1 487 ? 47.275 76.680 -3.265 1.00 9.90 ? 487 GLU A O 1 ATOM 3928 C CB . GLU A 1 487 ? 44.139 77.713 -2.946 1.00 10.76 ? 487 GLU A CB 1 ATOM 3929 C CG . GLU A 1 487 ? 44.489 78.260 -4.325 1.00 11.67 ? 487 GLU A CG 1 ATOM 3930 C CD . GLU A 1 487 ? 43.628 79.433 -4.800 1.00 18.47 ? 487 GLU A CD 1 ATOM 3931 O OE1 . GLU A 1 487 ? 42.503 79.611 -4.341 1.00 18.97 ? 487 GLU A OE1 1 ATOM 3932 O OE2 . GLU A 1 487 ? 44.137 80.185 -5.668 1.00 20.99 ? 487 GLU A OE2 1 ATOM 3933 N N . GLN A 1 488 ? 46.769 77.584 -1.270 1.00 9.43 ? 488 GLN A N 1 ATOM 3934 C CA . GLN A 1 488 ? 48.167 78.037 -1.048 1.00 10.32 ? 488 GLN A CA 1 ATOM 3935 C C . GLN A 1 488 ? 49.072 76.834 -0.941 1.00 10.35 ? 488 GLN A C 1 ATOM 3936 O O . GLN A 1 488 ? 50.192 76.840 -1.490 1.00 10.58 ? 488 GLN A O 1 ATOM 3937 C CB . GLN A 1 488 ? 48.252 78.828 0.281 1.00 14.85 ? 488 GLN A CB 1 ATOM 3938 C CG . GLN A 1 488 ? 47.526 80.171 0.183 1.00 23.99 ? 488 GLN A CG 1 ATOM 3939 C CD . GLN A 1 488 ? 47.654 81.053 1.441 1.00 32.93 ? 488 GLN A CD 1 ATOM 3940 O OE1 . GLN A 1 488 ? 47.435 82.262 1.369 1.00 41.49 ? 488 GLN A OE1 1 ATOM 3941 N NE2 . GLN A 1 488 ? 47.981 80.455 2.578 1.00 37.95 ? 488 GLN A NE2 1 ATOM 3942 N N . ARG A 1 489 ? 48.660 75.784 -0.251 1.00 8.80 ? 489 ARG A N 1 ATOM 3943 C CA . ARG A 1 489 ? 49.463 74.582 -0.167 1.00 9.63 ? 489 ARG A CA 1 ATOM 3944 C C . ARG A 1 489 ? 49.675 73.988 -1.558 1.00 9.91 ? 489 ARG A C 1 ATOM 3945 O O . ARG A 1 489 ? 50.789 73.602 -1.915 1.00 8.80 ? 489 ARG A O 1 ATOM 3946 C CB . ARG A 1 489 ? 48.742 73.571 0.748 1.00 9.26 ? 489 ARG A CB 1 ATOM 3947 C CG . ARG A 1 489 ? 48.843 73.936 2.179 1.00 8.50 ? 489 ARG A CG 1 ATOM 3948 C CD . ARG A 1 489 ? 47.870 73.026 2.992 1.00 9.81 ? 489 ARG A CD 1 ATOM 3949 N NE . ARG A 1 489 ? 47.951 73.179 4.461 1.00 9.97 ? 489 ARG A NE 1 ATOM 3950 C CZ . ARG A 1 489 ? 48.831 72.524 5.227 1.00 11.83 ? 489 ARG A CZ 1 ATOM 3951 N NH1 . ARG A 1 489 ? 49.707 71.674 4.706 1.00 13.99 ? 489 ARG A NH1 1 ATOM 3952 N NH2 . ARG A 1 489 ? 48.805 72.764 6.551 1.00 12.82 ? 489 ARG A NH2 1 ATOM 3953 N N . MET A 1 490 ? 48.634 73.907 -2.388 1.00 8.25 ? 490 MET A N 1 ATOM 3954 C CA . MET A 1 490 ? 48.787 73.359 -3.732 1.00 8.34 ? 490 MET A CA 1 ATOM 3955 C C . MET A 1 490 ? 49.661 74.251 -4.612 1.00 8.50 ? 490 MET A C 1 ATOM 3956 O O . MET A 1 490 ? 50.402 73.744 -5.459 1.00 9.28 ? 490 MET A O 1 ATOM 3957 C CB . MET A 1 490 ? 47.447 73.107 -4.413 1.00 8.42 ? 490 MET A CB 1 ATOM 3958 C CG . MET A 1 490 ? 46.726 71.902 -3.769 1.00 9.75 ? 490 MET A CG 1 ATOM 3959 S SD . MET A 1 490 ? 45.376 71.230 -4.857 1.00 12.76 ? 490 MET A SD 1 ATOM 3960 C CE . MET A 1 490 ? 44.119 72.397 -4.462 1.00 13.69 ? 490 MET A CE 1 ATOM 3961 N N . GLN A 1 491 ? 49.612 75.574 -4.427 1.00 8.59 ? 491 GLN A N 1 ATOM 3962 C CA . GLN A 1 491 ? 50.497 76.469 -5.209 1.00 9.16 ? 491 GLN A CA 1 ATOM 3963 C C . GLN A 1 491 ? 51.962 76.216 -4.857 1.00 10.25 ? 491 GLN A C 1 ATOM 3964 O O . GLN A 1 491 ? 52.820 76.144 -5.743 1.00 10.44 ? 491 GLN A O 1 ATOM 3965 C CB . GLN A 1 491 ? 50.194 77.931 -4.883 1.00 12.32 ? 491 GLN A CB 1 ATOM 3966 C CG . GLN A 1 491 ? 50.946 78.866 -5.819 1.00 18.34 ? 491 GLN A CG 1 ATOM 3967 C CD . GLN A 1 491 ? 50.656 78.582 -7.284 1.00 29.41 ? 491 GLN A CD 1 ATOM 3968 O OE1 . GLN A 1 491 ? 51.524 78.077 -8.043 1.00 32.19 ? 491 GLN A OE1 1 ATOM 3969 N NE2 . GLN A 1 491 ? 49.439 78.868 -7.684 1.00 34.17 ? 491 GLN A NE2 1 ATOM 3970 N N . GLU A 1 492 ? 52.240 76.003 -3.583 1.00 9.59 ? 492 GLU A N 1 ATOM 3971 C CA . GLU A 1 492 ? 53.597 75.698 -3.179 1.00 10.71 ? 492 GLU A CA 1 ATOM 3972 C C . GLU A 1 492 ? 54.004 74.382 -3.770 1.00 10.42 ? 492 GLU A C 1 ATOM 3973 O O . GLU A 1 492 ? 55.153 74.209 -4.214 1.00 10.47 ? 492 GLU A O 1 ATOM 3974 C CB . GLU A 1 492 ? 53.719 75.637 -1.640 1.00 12.49 ? 492 GLU A CB 1 ATOM 3975 C CG . GLU A 1 492 ? 53.626 77.044 -0.949 1.00 19.07 ? 492 GLU A CG 1 ATOM 3976 C CD . GLU A 1 492 ? 54.581 78.106 -1.553 1.00 27.89 ? 492 GLU A CD 1 ATOM 3977 O OE1 . GLU A 1 492 ? 54.094 79.188 -1.938 1.00 34.24 ? 492 GLU A OE1 1 ATOM 3978 O OE2 . GLU A 1 492 ? 55.825 77.894 -1.650 1.00 32.46 ? 492 GLU A OE2 1 ATOM 3979 N N . ALA A 1 493 ? 53.084 73.412 -3.777 1.00 9.03 ? 493 ALA A N 1 ATOM 3980 C CA . ALA A 1 493 ? 53.405 72.117 -4.372 1.00 8.60 ? 493 ALA A CA 1 ATOM 3981 C C . ALA A 1 493 ? 53.713 72.244 -5.894 1.00 7.86 ? 493 ALA A C 1 ATOM 3982 O O . ALA A 1 493 ? 54.610 71.554 -6.394 1.00 8.42 ? 493 ALA A O 1 ATOM 3983 C CB . ALA A 1 493 ? 52.192 71.124 -4.148 1.00 8.23 ? 493 ALA A CB 1 ATOM 3984 N N . LEU A 1 494 ? 52.922 73.044 -6.620 1.00 8.22 ? 494 LEU A N 1 ATOM 3985 C CA . LEU A 1 494 ? 53.190 73.253 -8.039 1.00 8.44 ? 494 LEU A CA 1 ATOM 3986 C C . LEU A 1 494 ? 54.597 73.844 -8.225 1.00 8.83 ? 494 LEU A C 1 ATOM 3987 O O . LEU A 1 494 ? 55.298 73.420 -9.134 1.00 9.81 ? 494 LEU A O 1 ATOM 3988 C CB . LEU A 1 494 ? 52.125 74.169 -8.672 1.00 10.42 ? 494 LEU A CB 1 ATOM 3989 C CG . LEU A 1 494 ? 50.765 73.516 -8.873 1.00 10.33 ? 494 LEU A CG 1 ATOM 3990 C CD1 . LEU A 1 494 ? 49.732 74.625 -9.202 1.00 12.04 ? 494 LEU A CD1 1 ATOM 3991 C CD2 . LEU A 1 494 ? 50.838 72.488 -9.983 1.00 10.76 ? 494 LEU A CD2 1 ATOM 3992 N N . LYS A 1 495 ? 54.981 74.803 -7.396 1.00 9.81 ? 495 LYS A N 1 ATOM 3993 C CA . LYS A 1 495 ? 56.330 75.401 -7.506 1.00 8.51 ? 495 LYS A CA 1 ATOM 3994 C C . LYS A 1 495 ? 57.391 74.366 -7.192 1.00 9.87 ? 495 LYS A C 1 ATOM 3995 O O . LYS A 1 495 ? 58.441 74.329 -7.869 1.00 10.21 ? 495 LYS A O 1 ATOM 3996 C CB . LYS A 1 495 ? 56.448 76.610 -6.560 1.00 12.33 ? 495 LYS A CB 1 ATOM 3997 C CG . LYS A 1 495 ? 55.595 77.810 -7.028 1.00 17.20 ? 495 LYS A CG 1 ATOM 3998 C CD . LYS A 1 495 ? 55.821 79.073 -6.167 1.00 26.49 ? 495 LYS A CD 1 ATOM 3999 C CE . LYS A 1 495 ? 55.550 78.796 -4.708 1.00 32.65 ? 495 LYS A CE 1 ATOM 4000 N NZ . LYS A 1 495 ? 55.775 79.998 -3.783 1.00 38.87 ? 495 LYS A NZ 1 ATOM 4001 N N . ALA A 1 496 ? 57.141 73.482 -6.229 1.00 7.99 ? 496 ALA A N 1 ATOM 4002 C CA . ALA A 1 496 ? 58.102 72.459 -5.926 1.00 8.46 ? 496 ALA A CA 1 ATOM 4003 C C . ALA A 1 496 ? 58.276 71.527 -7.135 1.00 9.38 ? 496 ALA A C 1 ATOM 4004 O O . ALA A 1 496 ? 59.397 71.117 -7.508 1.00 9.00 ? 496 ALA A O 1 ATOM 4005 C CB . ALA A 1 496 ? 57.617 71.644 -4.658 1.00 9.11 ? 496 ALA A CB 1 ATOM 4006 N N . CYS A 1 497 ? 57.166 71.128 -7.759 1.00 7.92 ? 497 CYS A N 1 ATOM 4007 C CA . CYS A 1 497 ? 57.229 70.249 -8.931 1.00 8.81 ? 497 CYS A CA 1 ATOM 4008 C C . CYS A 1 497 ? 57.981 70.943 -10.069 1.00 8.86 ? 497 CYS A C 1 ATOM 4009 O O . CYS A 1 497 ? 58.780 70.303 -10.728 1.00 9.06 ? 497 CYS A O 1 ATOM 4010 C CB . CYS A 1 497 ? 55.818 69.832 -9.414 1.00 7.69 ? 497 CYS A CB 1 ATOM 4011 S SG . CYS A 1 497 ? 54.938 68.754 -8.329 1.00 8.93 ? 497 CYS A SG 1 ATOM 4012 N N . GLN A 1 498 ? 57.710 72.210 -10.296 1.00 8.19 ? 498 GLN A N 1 ATOM 4013 C CA . GLN A 1 498 ? 58.413 72.923 -11.379 1.00 9.42 ? 498 GLN A CA 1 ATOM 4014 C C . GLN A 1 498 ? 59.918 72.892 -11.115 1.00 9.34 ? 498 GLN A C 1 ATOM 4015 O O . GLN A 1 498 ? 60.694 72.676 -12.075 1.00 9.77 ? 498 GLN A O 1 ATOM 4016 C CB . GLN A 1 498 ? 57.933 74.376 -11.464 1.00 10.63 ? 498 GLN A CB 1 ATOM 4017 C CG . GLN A 1 498 ? 58.770 75.187 -12.450 1.00 17.76 ? 498 GLN A CG 1 ATOM 4018 C CD . GLN A 1 498 ? 58.326 76.628 -12.550 1.00 20.79 ? 498 GLN A CD 1 ATOM 4019 O OE1 . GLN A 1 498 ? 58.233 77.349 -11.490 1.00 25.76 ? 498 GLN A OE1 1 ATOM 4020 N NE2 . GLN A 1 498 ? 58.097 77.109 -13.773 1.00 16.96 ? 498 GLN A NE2 1 ATOM 4021 N N . MET A 1 499 ? 60.347 73.168 -9.888 1.00 8.80 ? 499 MET A N 1 ATOM 4022 C CA . MET A 1 499 ? 61.771 73.162 -9.575 1.00 9.20 ? 499 MET A CA 1 ATOM 4023 C C . MET A 1 499 ? 62.398 71.837 -9.888 1.00 9.76 ? 499 MET A C 1 ATOM 4024 O O . MET A 1 499 ? 63.433 71.771 -10.561 1.00 10.21 ? 499 MET A O 1 ATOM 4025 C CB . MET A 1 499 ? 61.948 73.524 -8.109 1.00 10.92 ? 499 MET A CB 1 ATOM 4026 C CG . MET A 1 499 ? 63.394 73.398 -7.600 1.00 13.50 ? 499 MET A CG 1 ATOM 4027 S SD . MET A 1 499 ? 64.691 74.366 -8.425 1.00 19.89 ? 499 MET A SD 1 ATOM 4028 C CE . MET A 1 499 ? 64.011 75.839 -8.016 1.00 18.75 ? 499 MET A CE 1 ATOM 4029 N N . VAL A 1 500 ? 61.768 70.739 -9.442 1.00 7.98 ? 500 VAL A N 1 ATOM 4030 C CA . VAL A 1 500 ? 62.322 69.420 -9.653 1.00 7.73 ? 500 VAL A CA 1 ATOM 4031 C C . VAL A 1 500 ? 62.348 69.109 -11.150 1.00 8.02 ? 500 VAL A C 1 ATOM 4032 O O . VAL A 1 500 ? 63.357 68.557 -11.668 1.00 8.78 ? 500 VAL A O 1 ATOM 4033 C CB . VAL A 1 500 ? 61.518 68.373 -8.880 1.00 8.08 ? 500 VAL A CB 1 ATOM 4034 C CG1 . VAL A 1 500 ? 61.956 66.991 -9.299 1.00 9.56 ? 500 VAL A CG1 1 ATOM 4035 C CG2 . VAL A 1 500 ? 61.725 68.578 -7.372 1.00 10.37 ? 500 VAL A CG2 1 ATOM 4036 N N . MET A 1 501 ? 61.260 69.393 -11.858 1.00 8.05 ? 501 MET A N 1 ATOM 4037 C CA . MET A 1 501 ? 61.181 69.102 -13.292 1.00 8.63 ? 501 MET A CA 1 ATOM 4038 C C . MET A 1 501 ? 62.272 69.850 -14.052 1.00 9.11 ? 501 MET A C 1 ATOM 4039 O O . MET A 1 501 ? 62.933 69.235 -14.917 1.00 8.78 ? 501 MET A O 1 ATOM 4040 C CB . MET A 1 501 ? 59.814 69.497 -13.844 1.00 10.23 ? 501 MET A CB 1 ATOM 4041 C CG . MET A 1 501 ? 58.691 68.578 -13.331 1.00 9.25 ? 501 MET A CG 1 ATOM 4042 S SD . MET A 1 501 ? 57.009 69.251 -13.555 1.00 14.81 ? 501 MET A SD 1 ATOM 4043 C CE . MET A 1 501 ? 57.042 68.833 -14.884 1.00 12.83 ? 501 MET A CE 1 ATOM 4044 N N . GLN A 1 502 ? 62.455 71.150 -13.804 1.00 9.76 ? 502 GLN A N 1 ATOM 4045 C CA . GLN A 1 502 ? 63.418 71.903 -14.624 1.00 8.57 ? 502 GLN A CA 1 ATOM 4046 C C . GLN A 1 502 ? 64.847 71.518 -14.291 1.00 10.63 ? 502 GLN A C 1 ATOM 4047 O O . GLN A 1 502 ? 65.669 71.442 -15.224 1.00 9.96 ? 502 GLN A O 1 ATOM 4048 C CB . GLN A 1 502 ? 63.130 73.377 -14.528 1.00 11.76 ? 502 GLN A CB 1 ATOM 4049 C CG . GLN A 1 502 ? 63.323 74.044 -13.177 1.00 11.90 ? 502 GLN A CG 1 ATOM 4050 C CD . GLN A 1 502 ? 64.773 74.502 -12.945 1.00 13.25 ? 502 GLN A CD 1 ATOM 4051 O OE1 . GLN A 1 502 ? 65.581 74.647 -13.942 1.00 13.05 ? 502 GLN A OE1 1 ATOM 4052 N NE2 . GLN A 1 502 ? 65.128 74.758 -11.681 1.00 13.43 ? 502 GLN A NE2 1 ATOM 4053 N N . GLN A 1 503 ? 65.156 71.208 -13.041 1.00 8.74 ? 503 GLN A N 1 ATOM 4054 C CA . GLN A 1 503 ? 66.521 70.700 -12.760 1.00 10.41 ? 503 GLN A CA 1 ATOM 4055 C C . GLN A 1 503 ? 66.710 69.392 -13.476 1.00 9.13 ? 503 GLN A C 1 ATOM 4056 O O . GLN A 1 503 ? 67.820 69.096 -13.981 1.00 10.61 ? 503 GLN A O 1 ATOM 4057 C CB . GLN A 1 503 ? 66.707 70.473 -11.244 1.00 10.71 ? 503 GLN A CB 1 ATOM 4058 C CG . GLN A 1 503 ? 66.864 71.764 -10.414 1.00 12.24 ? 503 GLN A CG 1 ATOM 4059 C CD . GLN A 1 503 ? 68.228 72.433 -10.581 1.00 13.93 ? 503 GLN A CD 1 ATOM 4060 O OE1 . GLN A 1 503 ? 69.241 71.778 -10.876 1.00 15.20 ? 503 GLN A OE1 1 ATOM 4061 N NE2 . GLN A 1 503 ? 68.262 73.722 -10.326 1.00 15.02 ? 503 GLN A NE2 1 ATOM 4062 N N . SER A 1 504 ? 65.698 68.520 -13.550 1.00 8.17 ? 504 SER A N 1 ATOM 4063 C CA . SER A 1 504 ? 65.864 67.226 -14.181 1.00 9.10 ? 504 SER A CA 1 ATOM 4064 C C . SER A 1 504 ? 66.043 67.377 -15.703 1.00 9.21 ? 504 SER A C 1 ATOM 4065 O O . SER A 1 504 ? 66.873 66.677 -16.292 1.00 9.37 ? 504 SER A O 1 ATOM 4066 C CB . SER A 1 504 ? 64.603 66.336 -13.937 1.00 9.12 ? 504 SER A CB 1 ATOM 4067 O OG . SER A 1 504 ? 64.455 66.063 -12.533 1.00 9.91 ? 504 SER A OG 1 ATOM 4068 N N . VAL A 1 505 ? 65.253 68.227 -16.361 1.00 8.63 ? 505 VAL A N 1 ATOM 4069 C CA . VAL A 1 505 ? 65.420 68.435 -17.803 1.00 9.77 ? 505 VAL A CA 1 ATOM 4070 C C . VAL A 1 505 ? 66.865 68.959 -18.085 1.00 9.62 ? 505 VAL A C 1 ATOM 4071 O O . VAL A 1 505 ? 67.532 68.475 -19.042 1.00 10.67 ? 505 VAL A O 1 ATOM 4072 C CB . VAL A 1 505 ? 64.375 69.473 -18.308 1.00 9.50 ? 505 VAL A CB 1 ATOM 4073 C CG1 . VAL A 1 505 ? 64.711 69.915 -19.779 1.00 11.29 ? 505 VAL A CG1 1 ATOM 4074 C CG2 . VAL A 1 505 ? 62.967 68.857 -18.224 1.00 11.35 ? 505 VAL A CG2 1 ATOM 4075 N N A TYR A 1 506 ? 67.350 69.871 -17.279 0.50 8.75 ? 506 TYR A N 1 ATOM 4076 N N B TYR A 1 506 ? 67.350 69.871 -17.279 0.50 9.76 ? 506 TYR A N 1 ATOM 4077 C CA A TYR A 1 506 ? 68.680 70.390 -17.545 0.50 9.85 ? 506 TYR A CA 1 ATOM 4078 C CA B TYR A 1 506 ? 68.680 70.390 -17.545 0.50 11.65 ? 506 TYR A CA 1 ATOM 4079 C C A TYR A 1 506 ? 69.710 69.253 -17.452 0.50 11.15 ? 506 TYR A C 1 ATOM 4080 C C B TYR A 1 506 ? 69.710 69.253 -17.452 0.50 12.20 ? 506 TYR A C 1 ATOM 4081 O O A TYR A 1 506 ? 70.629 69.117 -18.294 0.50 11.73 ? 506 TYR A O 1 ATOM 4082 O O B TYR A 1 506 ? 70.629 69.117 -18.294 0.50 12.50 ? 506 TYR A O 1 ATOM 4083 C CB A TYR A 1 506 ? 68.989 71.509 -16.547 0.50 8.44 ? 506 TYR A CB 1 ATOM 4084 C CB B TYR A 1 506 ? 68.989 71.509 -16.547 0.50 12.84 ? 506 TYR A CB 1 ATOM 4085 C CG A TYR A 1 506 ? 70.291 72.185 -16.811 0.50 10.09 ? 506 TYR A CG 1 ATOM 4086 C CG B TYR A 1 506 ? 70.432 71.882 -16.515 0.50 17.12 ? 506 TYR A CG 1 ATOM 4087 C CD1 A TYR A 1 506 ? 70.484 72.773 -18.092 0.50 10.06 ? 506 TYR A CD1 1 ATOM 4088 C CD1 B TYR A 1 506 ? 71.069 72.170 -17.754 0.50 20.58 ? 506 TYR A CD1 1 ATOM 4089 C CD2 A TYR A 1 506 ? 71.294 72.198 -15.879 0.50 9.84 ? 506 TYR A CD2 1 ATOM 4090 C CD2 B TYR A 1 506 ? 71.142 71.897 -15.344 0.50 16.69 ? 506 TYR A CD2 1 ATOM 4091 C CE1 A TYR A 1 506 ? 71.666 73.366 -18.440 0.50 14.80 ? 506 TYR A CE1 1 ATOM 4092 C CE1 B TYR A 1 506 ? 72.402 72.467 -17.824 0.50 22.06 ? 506 TYR A CE1 1 ATOM 4093 C CE2 A TYR A 1 506 ? 72.584 72.819 -16.250 0.50 13.01 ? 506 TYR A CE2 1 ATOM 4094 C CE2 B TYR A 1 506 ? 72.589 72.198 -15.409 0.50 20.22 ? 506 TYR A CE2 1 ATOM 4095 C CZ A TYR A 1 506 ? 72.682 73.388 -17.543 0.50 9.60 ? 506 TYR A CZ 1 ATOM 4096 C CZ B TYR A 1 506 ? 73.136 72.482 -16.684 0.50 20.83 ? 506 TYR A CZ 1 ATOM 4097 O OH A TYR A 1 506 ? 73.778 74.153 -17.907 0.50 14.18 ? 506 TYR A OH 1 ATOM 4098 O OH B TYR A 1 506 ? 74.430 72.958 -16.818 0.50 18.98 ? 506 TYR A OH 1 ATOM 4099 N N . ARG A 1 507 ? 69.568 68.373 -16.478 1.00 10.21 ? 507 ARG A N 1 ATOM 4100 C CA . ARG A 1 507 ? 70.510 67.274 -16.333 1.00 10.33 ? 507 ARG A CA 1 ATOM 4101 C C . ARG A 1 507 ? 70.360 66.242 -17.439 1.00 10.45 ? 507 ARG A C 1 ATOM 4102 O O . ARG A 1 507 ? 71.372 65.687 -17.931 1.00 11.35 ? 507 ARG A O 1 ATOM 4103 C CB . ARG A 1 507 ? 70.336 66.606 -14.952 1.00 10.90 ? 507 ARG A CB 1 ATOM 4104 C CG . ARG A 1 507 ? 71.485 65.595 -14.660 1.00 12.77 ? 507 ARG A CG 1 ATOM 4105 C CD . ARG A 1 507 ? 71.280 65.102 -13.221 1.00 13.02 ? 507 ARG A CD 1 ATOM 4106 N NE . ARG A 1 507 ? 72.336 64.141 -12.810 1.00 15.95 ? 507 ARG A NE 1 ATOM 4107 C CZ . ARG A 1 507 ? 72.380 63.588 -11.581 1.00 16.43 ? 507 ARG A CZ 1 ATOM 4108 N NH1 . ARG A 1 507 ? 71.507 63.895 -10.670 1.00 17.54 ? 507 ARG A NH1 1 ATOM 4109 N NH2 . ARG A 1 507 ? 73.228 62.598 -11.308 1.00 18.92 ? 507 ARG A NH2 1 ATOM 4110 N N . LEU A 1 508 ? 69.147 65.958 -17.876 1.00 9.94 ? 508 LEU A N 1 ATOM 4111 C CA . LEU A 1 508 ? 68.915 64.946 -18.887 1.00 9.58 ? 508 LEU A CA 1 ATOM 4112 C C . LEU A 1 508 ? 69.345 65.341 -20.291 1.00 10.34 ? 508 LEU A C 1 ATOM 4113 O O . LEU A 1 508 ? 69.579 64.478 -21.128 1.00 11.68 ? 508 LEU A O 1 ATOM 4114 C CB . LEU A 1 508 ? 67.416 64.565 -18.925 1.00 9.35 ? 508 LEU A CB 1 ATOM 4115 C CG . LEU A 1 508 ? 66.985 63.708 -17.706 1.00 9.29 ? 508 LEU A CG 1 ATOM 4116 C CD1 . LEU A 1 508 ? 65.442 63.826 -17.589 1.00 9.84 ? 508 LEU A CD1 1 ATOM 4117 C CD2 . LEU A 1 508 ? 67.395 62.267 -17.805 1.00 12.38 ? 508 LEU A CD2 1 ATOM 4118 N N . LEU A 1 509 ? 69.410 66.649 -20.550 1.00 10.50 ? 509 LEU A N 1 ATOM 4119 C CA . LEU A 1 509 ? 69.709 67.180 -21.890 1.00 9.92 ? 509 LEU A CA 1 ATOM 4120 C C . LEU A 1 509 ? 70.979 67.998 -21.982 1.00 11.18 ? 509 LEU A C 1 ATOM 4121 O O . LEU A 1 509 ? 71.127 68.735 -22.970 1.00 12.56 ? 509 LEU A O 1 ATOM 4122 C CB . LEU A 1 509 ? 68.455 67.952 -22.413 1.00 9.54 ? 509 LEU A CB 1 ATOM 4123 C CG . LEU A 1 509 ? 67.244 67.074 -22.702 1.00 10.19 ? 509 LEU A CG 1 ATOM 4124 C CD1 . LEU A 1 509 ? 66.098 68.056 -23.127 1.00 10.09 ? 509 LEU A CD1 1 ATOM 4125 C CD2 . LEU A 1 509 ? 67.477 66.041 -23.849 1.00 12.41 ? 509 LEU A CD2 1 ATOM 4126 N N . THR A 1 510 ? 71.892 67.875 -21.013 1.00 9.88 ? 510 THR A N 1 ATOM 4127 C CA . THR A 1 510 ? 73.154 68.616 -21.120 1.00 11.57 ? 510 THR A CA 1 ATOM 4128 C C . THR A 1 510 ? 74.297 67.597 -21.146 1.00 12.47 ? 510 THR A C 1 ATOM 4129 O O . THR A 1 510 ? 74.321 66.626 -20.366 1.00 13.08 ? 510 THR A O 1 ATOM 4130 C CB . THR A 1 510 ? 73.326 69.591 -19.964 1.00 11.02 ? 510 THR A CB 1 ATOM 4131 O OG1 . THR A 1 510 ? 72.235 70.511 -19.953 1.00 12.35 ? 510 THR A OG1 1 ATOM 4132 C CG2 . THR A 1 510 ? 74.650 70.424 -20.085 1.00 11.95 ? 510 THR A CG2 1 ATOM 4133 N N . LYS A 1 511 ? 75.259 67.838 -22.046 1.00 13.78 ? 511 LYS A N 1 ATOM 4134 C CA . LYS A 1 511 ? 76.460 66.951 -22.148 1.00 16.15 ? 511 LYS A CA 1 ATOM 4135 C C . LYS A 1 511 ? 76.978 66.782 -20.747 1.00 13.85 ? 511 LYS A C 1 ATOM 4136 O O . LYS A 1 511 ? 77.260 67.744 -20.029 1.00 13.31 ? 511 LYS A O 1 ATOM 4137 C CB . LYS A 1 511 ? 77.514 67.600 -23.070 1.00 18.93 ? 511 LYS A CB 1 ATOM 4138 C CG . LYS A 1 511 ? 78.770 66.703 -23.127 1.00 25.46 ? 511 LYS A CG 1 ATOM 4139 C CD . LYS A 1 511 ? 79.866 67.117 -24.098 1.00 29.96 ? 511 LYS A CD 1 ATOM 4140 C CE . LYS A 1 511 ? 80.961 66.006 -23.966 1.00 31.98 ? 511 LYS A CE 1 ATOM 4141 N NZ . LYS A 1 511 ? 82.263 66.095 -24.731 1.00 34.40 ? 511 LYS A NZ 1 ATOM 4142 N N . PRO A 1 512 ? 77.211 65.523 -20.322 1.00 16.63 ? 512 PRO A N 1 ATOM 4143 C CA . PRO A 1 512 ? 77.665 65.335 -18.947 1.00 16.32 ? 512 PRO A CA 1 ATOM 4144 C C . PRO A 1 512 ? 78.890 66.067 -18.398 1.00 14.82 ? 512 PRO A C 1 ATOM 4145 O O . PRO A 1 512 ? 78.933 66.493 -17.265 1.00 16.13 ? 512 PRO A O 1 ATOM 4146 C CB . PRO A 1 512 ? 77.828 63.817 -18.837 1.00 21.42 ? 512 PRO A CB 1 ATOM 4147 C CG . PRO A 1 512 ? 76.872 63.293 -19.827 1.00 21.32 ? 512 PRO A CG 1 ATOM 4148 C CD . PRO A 1 512 ? 76.852 64.245 -20.978 1.00 17.82 ? 512 PRO A CD 1 ATOM 4149 N N . SER A 1 513 ? 79.886 66.168 -19.257 1.00 15.70 ? 513 SER A N 1 ATOM 4150 C CA . SER A 1 513 ? 81.134 66.827 -18.806 1.00 15.45 ? 513 SER A CA 1 ATOM 4151 C C . SER A 1 513 ? 81.040 68.346 -18.784 1.00 14.86 ? 513 SER A C 1 ATOM 4152 O O . SER A 1 513 ? 82.000 69.029 -18.394 1.00 16.70 ? 513 SER A O 1 ATOM 4153 C CB . SER A 1 513 ? 82.309 66.374 -19.707 1.00 16.06 ? 513 SER A CB 1 ATOM 4154 O OG . SER A 1 513 ? 82.008 66.710 -21.020 1.00 18.39 ? 513 SER A OG 1 ATOM 4155 N N . ILE A 1 514 ? 79.888 68.885 -19.196 1.00 15.79 ? 514 ILE A N 1 ATOM 4156 C CA . ILE A 1 514 ? 79.602 70.324 -19.218 1.00 15.36 ? 514 ILE A CA 1 ATOM 4157 C C . ILE A 1 514 ? 78.601 70.670 -18.089 1.00 14.76 ? 514 ILE A C 1 ATOM 4158 O O . ILE A 1 514 ? 78.659 71.745 -17.514 1.00 15.15 ? 514 ILE A O 1 ATOM 4159 C CB . ILE A 1 514 ? 78.987 70.733 -20.630 1.00 17.44 ? 514 ILE A CB 1 ATOM 4160 C CG1 . ILE A 1 514 ? 80.065 70.589 -21.701 1.00 21.61 ? 514 ILE A CG1 1 ATOM 4161 C CG2 . ILE A 1 514 ? 78.337 72.117 -20.559 1.00 20.00 ? 514 ILE A CG2 1 ATOM 4162 C CD1 . ILE A 1 514 ? 79.643 71.038 -23.110 1.00 26.63 ? 514 ILE A CD1 1 ATOM 4163 N N . TYR A 1 515 ? 77.722 69.725 -17.746 1.00 13.55 ? 515 TYR A N 1 ATOM 4164 C CA . TYR A 1 515 ? 76.679 69.956 -16.738 1.00 12.74 ? 515 TYR A CA 1 ATOM 4165 C C . TYR A 1 515 ? 77.261 70.511 -15.452 1.00 13.60 ? 515 TYR A C 1 ATOM 4166 O O . TYR A 1 515 ? 78.121 69.875 -14.833 1.00 14.44 ? 515 TYR A O 1 ATOM 4167 C CB . TYR A 1 515 ? 75.996 68.600 -16.532 1.00 13.23 ? 515 TYR A CB 1 ATOM 4168 C CG . TYR A 1 515 ? 75.006 68.553 -15.420 1.00 12.82 ? 515 TYR A CG 1 ATOM 4169 C CD1 . TYR A 1 515 ? 73.840 69.286 -15.486 1.00 11.39 ? 515 TYR A CD1 1 ATOM 4170 C CD2 . TYR A 1 515 ? 75.222 67.734 -14.316 1.00 14.37 ? 515 TYR A CD2 1 ATOM 4171 C CE1 . TYR A 1 515 ? 72.870 69.203 -14.484 1.00 12.07 ? 515 TYR A CE1 1 ATOM 4172 C CE2 . TYR A 1 515 ? 74.266 67.649 -13.284 1.00 13.29 ? 515 TYR A CE2 1 ATOM 4173 C CZ . TYR A 1 515 ? 73.100 68.390 -13.406 1.00 13.10 ? 515 TYR A CZ 1 ATOM 4174 O OH . TYR A 1 515 ? 72.153 68.298 -12.401 1.00 13.54 ? 515 TYR A OH 1 ATOM 4175 N N . SER A 1 516 ? 76.786 71.686 -15.023 1.00 13.36 ? 516 SER A N 1 ATOM 4176 C CA . SER A 1 516 ? 77.312 72.326 -13.817 1.00 14.15 ? 516 SER A CA 1 ATOM 4177 C C . SER A 1 516 ? 76.152 72.979 -13.078 1.00 15.24 ? 516 SER A C 1 ATOM 4178 O O . SER A 1 516 ? 75.940 74.206 -13.115 1.00 16.90 ? 516 SER A O 1 ATOM 4179 C CB . SER A 1 516 ? 78.331 73.383 -14.269 1.00 16.76 ? 516 SER A CB 1 ATOM 4180 O OG . SER A 1 516 ? 79.078 73.878 -13.144 1.00 23.21 ? 516 SER A OG 1 ATOM 4181 N N . PRO A 1 517 ? 75.393 72.155 -12.347 1.00 14.73 ? 517 PRO A N 1 ATOM 4182 C CA . PRO A 1 517 ? 74.240 72.699 -11.670 1.00 16.74 ? 517 PRO A CA 1 ATOM 4183 C C . PRO A 1 517 ? 74.336 73.546 -10.456 1.00 17.19 ? 517 PRO A C 1 ATOM 4184 O O . PRO A 1 517 ? 75.195 73.315 -9.622 1.00 21.63 ? 517 PRO A O 1 ATOM 4185 C CB . PRO A 1 517 ? 73.406 71.448 -11.398 1.00 18.76 ? 517 PRO A CB 1 ATOM 4186 C CG . PRO A 1 517 ? 74.466 70.425 -11.076 1.00 18.44 ? 517 PRO A CG 1 ATOM 4187 C CD . PRO A 1 517 ? 75.559 70.711 -12.126 1.00 16.17 ? 517 PRO A CD 1 ATOM 4188 N N . ASP A 1 518 ? 73.508 74.564 -10.415 1.00 18.00 ? 518 ASP A N 1 ATOM 4189 C CA . ASP A 1 518 ? 73.322 75.361 -9.216 1.00 19.07 ? 518 ASP A CA 1 ATOM 4190 C C . ASP A 1 518 ? 71.881 74.882 -8.917 1.00 16.76 ? 518 ASP A C 1 ATOM 4191 O O . ASP A 1 518 ? 70.940 75.201 -9.648 1.00 16.06 ? 518 ASP A O 1 ATOM 4192 C CB . ASP A 1 518 ? 73.324 76.837 -9.554 1.00 21.21 ? 518 ASP A CB 1 ATOM 4193 C CG . ASP A 1 518 ? 72.862 77.706 -8.428 1.00 27.98 ? 518 ASP A CG 1 ATOM 4194 O OD1 . ASP A 1 518 ? 72.269 77.216 -7.429 1.00 23.17 ? 518 ASP A OD1 1 ATOM 4195 O OD2 . ASP A 1 518 ? 73.054 78.935 -8.575 1.00 29.29 ? 518 ASP A OD2 1 ATOM 4196 N N . PHE A 1 519 ? 71.736 74.146 -7.822 1.00 16.63 ? 519 PHE A N 1 ATOM 4197 C CA . PHE A 1 519 ? 70.436 73.571 -7.441 1.00 17.48 ? 519 PHE A CA 1 ATOM 4198 C C . PHE A 1 519 ? 69.362 74.547 -7.047 1.00 17.44 ? 519 PHE A C 1 ATOM 4199 O O . PHE A 1 519 ? 68.198 74.158 -6.882 1.00 18.52 ? 519 PHE A O 1 ATOM 4200 C CB . PHE A 1 519 ? 70.644 72.494 -6.362 1.00 15.25 ? 519 PHE A CB 1 ATOM 4201 C CG . PHE A 1 519 ? 71.485 71.339 -6.834 1.00 15.14 ? 519 PHE A CG 1 ATOM 4202 C CD1 . PHE A 1 519 ? 71.192 70.657 -8.025 1.00 16.37 ? 519 PHE A CD1 1 ATOM 4203 C CD2 . PHE A 1 519 ? 72.578 70.930 -6.066 1.00 15.99 ? 519 PHE A CD2 1 ATOM 4204 C CE1 . PHE A 1 519 ? 71.950 69.607 -8.458 1.00 14.92 ? 519 PHE A CE1 1 ATOM 4205 C CE2 . PHE A 1 519 ? 73.353 69.861 -6.488 1.00 15.68 ? 519 PHE A CE2 1 ATOM 4206 C CZ . PHE A 1 519 ? 73.040 69.187 -7.704 1.00 16.49 ? 519 PHE A CZ 1 ATOM 4207 N N . SER A 1 520 ? 69.695 75.837 -6.934 1.00 17.03 ? 520 SER A N 1 ATOM 4208 C CA . SER A 1 520 ? 68.685 76.854 -6.609 1.00 18.37 ? 520 SER A CA 1 ATOM 4209 C C . SER A 1 520 ? 68.320 77.683 -7.843 1.00 17.45 ? 520 SER A C 1 ATOM 4210 O O . SER A 1 520 ? 67.398 78.481 -7.781 1.00 18.39 ? 520 SER A O 1 ATOM 4211 C CB . SER A 1 520 ? 69.208 77.880 -5.584 1.00 18.67 ? 520 SER A CB 1 ATOM 4212 O OG . SER A 1 520 ? 70.260 78.661 -6.149 1.00 25.69 ? 520 SER A OG 1 ATOM 4213 N N . PHE A 1 521 ? 68.994 77.438 -8.972 1.00 16.97 ? 521 PHE A N 1 ATOM 4214 C CA . PHE A 1 521 ? 68.784 78.235 -10.188 1.00 17.01 ? 521 PHE A CA 1 ATOM 4215 C C . PHE A 1 521 ? 67.672 77.715 -11.086 1.00 14.89 ? 521 PHE A C 1 ATOM 4216 O O . PHE A 1 521 ? 67.456 76.481 -11.136 1.00 17.20 ? 521 PHE A O 1 ATOM 4217 C CB . PHE A 1 521 ? 70.140 78.265 -10.970 1.00 17.81 ? 521 PHE A CB 1 ATOM 4218 C CG . PHE A 1 521 ? 70.155 79.200 -12.151 1.00 18.47 ? 521 PHE A CG 1 ATOM 4219 C CD1 . PHE A 1 521 ? 70.305 80.582 -11.946 1.00 22.08 ? 521 PHE A CD1 1 ATOM 4220 C CD2 . PHE A 1 521 ? 69.960 78.709 -13.469 1.00 19.90 ? 521 PHE A CD2 1 ATOM 4221 C CE1 . PHE A 1 521 ? 70.244 81.470 -13.043 1.00 26.07 ? 521 PHE A CE1 1 ATOM 4222 C CE2 . PHE A 1 521 ? 69.897 79.589 -14.559 1.00 20.92 ? 521 PHE A CE2 1 ATOM 4223 C CZ . PHE A 1 521 ? 70.037 80.982 -14.345 1.00 24.08 ? 521 PHE A CZ 1 ATOM 4224 N N . SER A 1 522 ? 66.983 78.608 -11.798 1.00 17.19 ? 522 SER A N 1 ATOM 4225 C CA . SER A 1 522 ? 65.942 78.194 -12.736 1.00 17.06 ? 522 SER A CA 1 ATOM 4226 C C . SER A 1 522 ? 66.500 78.176 -14.149 1.00 14.23 ? 522 SER A C 1 ATOM 4227 O O . SER A 1 522 ? 66.610 79.220 -14.806 1.00 17.89 ? 522 SER A O 1 ATOM 4228 C CB . SER A 1 522 ? 64.734 79.136 -12.696 1.00 21.48 ? 522 SER A CB 1 ATOM 4229 O OG . SER A 1 522 ? 64.070 78.992 -11.436 1.00 30.02 ? 522 SER A OG 1 ATOM 4230 N N . TYR A 1 523 ? 66.893 76.998 -14.591 1.00 11.00 ? 523 TYR A N 1 ATOM 4231 C CA . TYR A 1 523 ? 67.351 76.796 -15.959 1.00 11.05 ? 523 TYR A CA 1 ATOM 4232 C C . TYR A 1 523 ? 66.222 76.866 -16.959 1.00 11.77 ? 523 TYR A C 1 ATOM 4233 O O . TYR A 1 523 ? 66.453 77.290 -18.102 1.00 11.37 ? 523 TYR A O 1 ATOM 4234 C CB . TYR A 1 523 ? 68.030 75.438 -16.085 1.00 12.22 ? 523 TYR A CB 1 ATOM 4235 C CG . TYR A 1 523 ? 69.306 75.369 -15.289 1.00 12.20 ? 523 TYR A CG 1 ATOM 4236 C CD1 . TYR A 1 523 ? 69.341 74.814 -14.021 1.00 12.70 ? 523 TYR A CD1 1 ATOM 4237 C CD2 . TYR A 1 523 ? 70.504 75.955 -15.806 1.00 13.68 ? 523 TYR A CD2 1 ATOM 4238 C CE1 . TYR A 1 523 ? 70.529 74.836 -13.283 1.00 15.22 ? 523 TYR A CE1 1 ATOM 4239 C CE2 . TYR A 1 523 ? 71.666 75.998 -15.077 1.00 15.23 ? 523 TYR A CE2 1 ATOM 4240 C CZ . TYR A 1 523 ? 71.671 75.443 -13.821 1.00 18.16 ? 523 TYR A CZ 1 ATOM 4241 O OH . TYR A 1 523 ? 72.793 75.538 -13.009 1.00 17.43 ? 523 TYR A OH 1 ATOM 4242 N N . PHE A 1 524 ? 65.007 76.463 -16.572 1.00 10.50 ? 524 PHE A N 1 ATOM 4243 C CA . PHE A 1 524 ? 63.848 76.518 -17.433 1.00 10.29 ? 524 PHE A CA 1 ATOM 4244 C C . PHE A 1 524 ? 62.687 76.991 -16.603 1.00 11.68 ? 524 PHE A C 1 ATOM 4245 O O . PHE A 1 524 ? 62.632 76.762 -15.395 1.00 12.65 ? 524 PHE A O 1 ATOM 4246 C CB . PHE A 1 524 ? 63.444 75.123 -17.979 1.00 10.92 ? 524 PHE A CB 1 ATOM 4247 C CG . PHE A 1 524 ? 64.482 74.467 -18.851 1.00 9.58 ? 524 PHE A CG 1 ATOM 4248 C CD1 . PHE A 1 524 ? 65.489 73.685 -18.285 1.00 10.77 ? 524 PHE A CD1 1 ATOM 4249 C CD2 . PHE A 1 524 ? 64.439 74.620 -20.248 1.00 10.48 ? 524 PHE A CD2 1 ATOM 4250 C CE1 . PHE A 1 524 ? 66.454 73.070 -19.095 1.00 12.75 ? 524 PHE A CE1 1 ATOM 4251 C CE2 . PHE A 1 524 ? 65.387 74.007 -21.062 1.00 10.20 ? 524 PHE A CE2 1 ATOM 4252 C CZ . PHE A 1 524 ? 66.404 73.235 -20.467 1.00 11.87 ? 524 PHE A CZ 1 ATOM 4253 N N . THR A 1 525 ? 61.783 77.638 -17.289 1.00 11.85 ? 525 THR A N 1 ATOM 4254 C CA . THR A 1 525 ? 60.515 77.957 -16.654 1.00 15.26 ? 525 THR A CA 1 ATOM 4255 C C . THR A 1 525 ? 59.448 77.148 -17.395 1.00 12.84 ? 525 THR A C 1 ATOM 4256 O O . THR A 1 525 ? 59.490 76.971 -18.661 1.00 14.16 ? 525 THR A O 1 ATOM 4257 C CB . THR A 1 525 ? 60.179 79.420 -16.692 1.00 19.69 ? 525 THR A CB 1 ATOM 4258 O OG1 . THR A 1 525 ? 59.935 79.790 -18.006 1.00 22.28 ? 525 THR A OG1 1 ATOM 4259 C CG2 . THR A 1 525 ? 61.381 80.278 -16.239 1.00 20.99 ? 525 THR A CG2 1 ATOM 4260 N N . LEU A 1 526 ? 58.472 76.622 -16.661 1.00 10.91 ? 526 LEU A N 1 ATOM 4261 C CA . LEU A 1 526 ? 57.382 75.901 -17.274 1.00 12.88 ? 526 LEU A CA 1 ATOM 4262 C C . LEU A 1 526 ? 56.430 76.866 -17.950 1.00 11.97 ? 526 LEU A C 1 ATOM 4263 O O . LEU A 1 526 ? 56.250 78.021 -17.500 1.00 16.99 ? 526 LEU A O 1 ATOM 4264 C CB . LEU A 1 526 ? 56.563 75.098 -16.223 1.00 16.32 ? 526 LEU A CB 1 ATOM 4265 C CG . LEU A 1 526 ? 57.021 73.694 -15.788 1.00 19.82 ? 526 LEU A CG 1 ATOM 4266 C CD1 . LEU A 1 526 ? 56.127 73.170 -14.620 1.00 24.73 ? 526 LEU A CD1 1 ATOM 4267 C CD2 . LEU A 1 526 ? 56.917 72.751 -16.950 1.00 18.19 ? 526 LEU A CD2 1 ATOM 4268 N N . ASP A 1 527 ? 55.831 76.432 -19.036 1.00 10.30 ? 527 ASP A N 1 ATOM 4269 C CA . ASP A 1 527 ? 54.839 77.219 -19.733 1.00 12.11 ? 527 ASP A CA 1 ATOM 4270 C C . ASP A 1 527 ? 53.603 76.329 -19.785 1.00 12.91 ? 527 ASP A C 1 ATOM 4271 O O . ASP A 1 527 ? 53.633 75.235 -20.318 1.00 17.02 ? 527 ASP A O 1 ATOM 4272 C CB . ASP A 1 527 ? 55.298 77.585 -21.163 1.00 12.91 ? 527 ASP A CB 1 ATOM 4273 C CG . ASP A 1 527 ? 54.302 78.484 -21.882 1.00 18.71 ? 527 ASP A CG 1 ATOM 4274 O OD1 . ASP A 1 527 ? 54.061 79.600 -21.418 1.00 17.58 ? 527 ASP A OD1 1 ATOM 4275 O OD2 . ASP A 1 527 ? 53.737 78.069 -22.914 1.00 20.01 ? 527 ASP A OD2 1 ATOM 4276 N N . ASP A 1 528 ? 52.523 76.764 -19.186 1.00 12.43 ? 528 ASP A N 1 ATOM 4277 C CA . ASP A 1 528 ? 51.298 75.942 -19.186 1.00 10.47 ? 528 ASP A CA 1 ATOM 4278 C C . ASP A 1 528 ? 50.195 76.795 -19.797 1.00 11.89 ? 528 ASP A C 1 ATOM 4279 O O . ASP A 1 528 ? 49.820 77.836 -19.251 1.00 12.43 ? 528 ASP A O 1 ATOM 4280 C CB . ASP A 1 528 ? 50.968 75.536 -17.730 1.00 11.39 ? 528 ASP A CB 1 ATOM 4281 C CG . ASP A 1 528 ? 49.862 74.494 -17.634 1.00 11.82 ? 528 ASP A CG 1 ATOM 4282 O OD1 . ASP A 1 528 ? 48.868 74.559 -18.372 1.00 13.72 ? 528 ASP A OD1 1 ATOM 4283 O OD2 . ASP A 1 528 ? 50.039 73.570 -16.790 1.00 15.41 ? 528 ASP A OD2 1 ATOM 4284 N N . SER A 1 529 ? 49.673 76.333 -20.929 1.00 12.20 ? 529 SER A N 1 ATOM 4285 C CA . SER A 1 529 ? 48.622 77.085 -21.626 1.00 11.77 ? 529 SER A CA 1 ATOM 4286 C C . SER A 1 529 ? 47.240 76.989 -21.019 1.00 12.22 ? 529 SER A C 1 ATOM 4287 O O . SER A 1 529 ? 46.378 77.760 -21.344 1.00 16.50 ? 529 SER A O 1 ATOM 4288 C CB . SER A 1 529 ? 48.434 76.615 -23.079 1.00 15.79 ? 529 SER A CB 1 ATOM 4289 O OG . SER A 1 529 ? 49.660 76.707 -23.739 1.00 18.12 ? 529 SER A OG 1 ATOM 4290 N N . ARG A 1 530 ? 47.011 76.037 -20.100 1.00 9.96 ? 530 ARG A N 1 ATOM 4291 C CA . ARG A 1 530 ? 45.653 75.831 -19.593 1.00 11.11 ? 530 ARG A CA 1 ATOM 4292 C C . ARG A 1 530 ? 45.523 75.923 -18.113 1.00 12.37 ? 530 ARG A C 1 ATOM 4293 O O . ARG A 1 530 ? 44.493 75.528 -17.555 1.00 17.76 ? 530 ARG A O 1 ATOM 4294 C CB . ARG A 1 530 ? 45.140 74.456 -20.098 1.00 9.82 ? 530 ARG A CB 1 ATOM 4295 C CG . ARG A 1 530 ? 45.136 74.410 -21.666 1.00 11.39 ? 530 ARG A CG 1 ATOM 4296 C CD . ARG A 1 530 ? 44.428 73.191 -22.256 1.00 12.17 ? 530 ARG A CD 1 ATOM 4297 N NE . ARG A 1 530 ? 45.123 71.991 -21.809 1.00 12.60 ? 530 ARG A NE 1 ATOM 4298 C CZ . ARG A 1 530 ? 44.916 70.782 -22.347 1.00 12.75 ? 530 ARG A CZ 1 ATOM 4299 N NH1 . ARG A 1 530 ? 44.042 70.633 -23.332 1.00 15.03 ? 530 ARG A NH1 1 ATOM 4300 N NH2 . ARG A 1 530 ? 45.573 69.753 -21.866 1.00 15.05 ? 530 ARG A NH2 1 ATOM 4301 N N . TRP A 1 531 ? 46.552 76.366 -17.430 1.00 9.61 ? 531 TRP A N 1 ATOM 4302 C CA . TRP A 1 531 ? 46.420 76.571 -15.969 1.00 9.78 ? 531 TRP A CA 1 ATOM 4303 C C . TRP A 1 531 ? 47.382 77.680 -15.546 1.00 10.09 ? 531 TRP A C 1 ATOM 4304 O O . TRP A 1 531 ? 48.574 77.596 -15.817 1.00 12.76 ? 531 TRP A O 1 ATOM 4305 C CB . TRP A 1 531 ? 46.749 75.317 -15.137 1.00 10.91 ? 531 TRP A CB 1 ATOM 4306 C CG . TRP A 1 531 ? 46.670 75.655 -13.671 1.00 12.68 ? 531 TRP A CG 1 ATOM 4307 C CD1 . TRP A 1 531 ? 47.717 76.077 -12.841 1.00 14.52 ? 531 TRP A CD1 1 ATOM 4308 C CD2 . TRP A 1 531 ? 45.496 75.757 -12.942 1.00 15.35 ? 531 TRP A CD2 1 ATOM 4309 N NE1 . TRP A 1 531 ? 47.203 76.428 -11.636 1.00 17.02 ? 531 TRP A NE1 1 ATOM 4310 C CE2 . TRP A 1 531 ? 45.845 76.252 -11.657 1.00 12.00 ? 531 TRP A CE2 1 ATOM 4311 C CE3 . TRP A 1 531 ? 44.202 75.490 -13.238 1.00 13.82 ? 531 TRP A CE3 1 ATOM 4312 C CZ2 . TRP A 1 531 ? 44.878 76.480 -10.633 1.00 16.22 ? 531 TRP A CZ2 1 ATOM 4313 C CZ3 . TRP A 1 531 ? 43.226 75.715 -12.243 1.00 13.65 ? 531 TRP A CZ3 1 ATOM 4314 C CH2 . TRP A 1 531 ? 43.580 76.204 -10.947 1.00 17.76 ? 531 TRP A CH2 1 ATOM 4315 N N . PRO A 1 532 ? 46.856 78.702 -14.845 1.00 11.28 ? 532 PRO A N 1 ATOM 4316 C CA . PRO A 1 532 ? 45.458 78.910 -14.446 1.00 11.36 ? 532 PRO A CA 1 ATOM 4317 C C . PRO A 1 532 ? 44.579 79.192 -15.677 1.00 12.68 ? 532 PRO A C 1 ATOM 4318 O O . PRO A 1 532 ? 43.353 79.042 -15.601 1.00 15.29 ? 532 PRO A O 1 ATOM 4319 C CB . PRO A 1 532 ? 45.533 80.121 -13.464 1.00 12.74 ? 532 PRO A CB 1 ATOM 4320 C CG . PRO A 1 532 ? 46.959 79.959 -12.868 1.00 14.96 ? 532 PRO A CG 1 ATOM 4321 C CD . PRO A 1 532 ? 47.768 79.629 -14.122 1.00 13.37 ? 532 PRO A CD 1 ATOM 4322 N N . GLY A 1 533 ? 45.195 79.581 -16.794 1.00 12.95 ? 533 GLY A N 1 ATOM 4323 C CA . GLY A 1 533 ? 44.480 79.792 -18.044 1.00 15.91 ? 533 GLY A CA 1 ATOM 4324 C C . GLY A 1 533 ? 44.260 81.253 -18.414 1.00 19.32 ? 533 GLY A C 1 ATOM 4325 O O . GLY A 1 533 ? 44.268 82.166 -17.564 1.00 17.74 ? 533 GLY A O 1 ATOM 4326 N N . SER A 1 534 ? 44.113 81.422 -19.732 1.00 21.64 ? 534 SER A N 1 ATOM 4327 C CA . SER A 1 534 ? 43.895 82.709 -20.385 1.00 23.10 ? 534 SER A CA 1 ATOM 4328 C C . SER A 1 534 ? 42.629 83.254 -19.745 1.00 21.85 ? 534 SER A C 1 ATOM 4329 O O . SER A 1 534 ? 41.595 82.555 -19.695 1.00 25.19 ? 534 SER A O 1 ATOM 4330 C CB . SER A 1 534 ? 43.689 82.459 -21.885 1.00 30.16 ? 534 SER A CB 1 ATOM 4331 O OG . SER A 1 534 ? 43.565 83.686 -22.579 1.00 36.25 ? 534 SER A OG 1 ATOM 4332 N N . GLY A 1 535 ? 42.693 84.480 -19.224 1.00 24.20 ? 535 GLY A N 1 ATOM 4333 C CA . GLY A 1 535 ? 41.519 85.048 -18.575 1.00 22.49 ? 535 GLY A CA 1 ATOM 4334 C C . GLY A 1 535 ? 41.374 84.761 -17.096 1.00 25.29 ? 535 GLY A C 1 ATOM 4335 O O . GLY A 1 535 ? 40.451 85.266 -16.420 1.00 26.48 ? 535 GLY A O 1 ATOM 4336 N N . VAL A 1 536 ? 42.260 83.908 -16.570 1.00 22.99 ? 536 VAL A N 1 ATOM 4337 C CA . VAL A 1 536 ? 42.229 83.559 -15.163 1.00 20.80 ? 536 VAL A CA 1 ATOM 4338 C C . VAL A 1 536 ? 43.432 84.233 -14.492 1.00 22.65 ? 536 VAL A C 1 ATOM 4339 O O . VAL A 1 536 ? 43.272 84.904 -13.455 1.00 21.07 ? 536 VAL A O 1 ATOM 4340 C CB . VAL A 1 536 ? 42.261 82.017 -15.009 1.00 17.75 ? 536 VAL A CB 1 ATOM 4341 C CG1 . VAL A 1 536 ? 42.107 81.606 -13.548 1.00 19.66 ? 536 VAL A CG1 1 ATOM 4342 C CG2 . VAL A 1 536 ? 41.045 81.419 -15.762 1.00 22.33 ? 536 VAL A CG2 1 ATOM 4343 N N . GLU A 1 537 ? 44.632 84.028 -15.036 1.00 21.88 ? 537 GLU A N 1 ATOM 4344 C CA . GLU A 1 537 ? 45.822 84.699 -14.496 1.00 24.82 ? 537 GLU A CA 1 ATOM 4345 C C . GLU A 1 537 ? 46.759 84.976 -15.678 1.00 25.62 ? 537 GLU A C 1 ATOM 4346 O O . GLU A 1 537 ? 46.854 84.149 -16.609 1.00 28.23 ? 537 GLU A O 1 ATOM 4347 C CB . GLU A 1 537 ? 46.553 83.815 -13.471 1.00 23.41 ? 537 GLU A CB 1 ATOM 4348 C CG . GLU A 1 537 ? 45.804 83.514 -12.150 1.00 29.48 ? 537 GLU A CG 1 ATOM 4349 C CD . GLU A 1 537 ? 45.438 84.731 -11.323 1.00 38.04 ? 537 GLU A CD 1 ATOM 4350 O OE1 . GLU A 1 537 ? 45.997 85.844 -11.537 1.00 38.22 ? 537 GLU A OE1 1 ATOM 4351 O OE2 . GLU A 1 537 ? 44.580 84.568 -10.424 1.00 37.31 ? 537 GLU A OE2 1 ATOM 4352 N N A ASP A 1 538 ? 47.440 86.132 -15.697 0.50 28.35 ? 538 ASP A N 1 ATOM 4353 N N B ASP A 1 538 ? 47.440 86.132 -15.697 0.50 28.99 ? 538 ASP A N 1 ATOM 4354 C CA A ASP A 1 538 ? 48.423 86.330 -16.806 0.50 31.87 ? 538 ASP A CA 1 ATOM 4355 C CA B ASP A 1 538 ? 48.423 86.330 -16.806 0.50 32.78 ? 538 ASP A CA 1 ATOM 4356 C C A ASP A 1 538 ? 49.683 85.822 -16.103 0.50 31.72 ? 538 ASP A C 1 ATOM 4357 C C B ASP A 1 538 ? 49.683 85.822 -16.103 0.50 32.28 ? 538 ASP A C 1 ATOM 4358 O O A ASP A 1 538 ? 50.323 86.538 -15.321 0.50 33.95 ? 538 ASP A O 1 ATOM 4359 O O B ASP A 1 538 ? 50.323 86.538 -15.321 0.50 34.38 ? 538 ASP A O 1 ATOM 4360 C CB A ASP A 1 538 ? 48.567 87.820 -17.242 0.50 36.09 ? 538 ASP A CB 1 ATOM 4361 C CB B ASP A 1 538 ? 48.567 87.820 -17.242 0.50 38.30 ? 538 ASP A CB 1 ATOM 4362 C CG A ASP A 1 538 ? 49.000 87.960 -18.744 0.50 39.70 ? 538 ASP A CG 1 ATOM 4363 C CG B ASP A 1 538 ? 48.381 88.007 -18.789 0.50 42.64 ? 538 ASP A CG 1 ATOM 4364 O OD1 A ASP A 1 538 ? 49.701 87.040 -19.235 0.50 39.72 ? 538 ASP A OD1 1 ATOM 4365 O OD1 B ASP A 1 538 ? 49.136 87.351 -19.549 0.50 44.13 ? 538 ASP A OD1 1 ATOM 4366 O OD2 A ASP A 1 538 ? 48.648 88.968 -19.441 0.50 39.30 ? 538 ASP A OD2 1 ATOM 4367 O OD2 B ASP A 1 538 ? 47.491 88.791 -19.257 0.50 45.80 ? 538 ASP A OD2 1 ATOM 4368 N N . SER A 1 539 ? 50.023 84.562 -16.344 1.00 29.37 ? 539 SER A N 1 ATOM 4369 C CA . SER A 1 539 ? 51.161 83.932 -15.647 1.00 28.19 ? 539 SER A CA 1 ATOM 4370 C C . SER A 1 539 ? 52.284 83.509 -16.584 1.00 27.12 ? 539 SER A C 1 ATOM 4371 O O . SER A 1 539 ? 53.397 83.233 -16.126 1.00 28.06 ? 539 SER A O 1 ATOM 4372 C CB . SER A 1 539 ? 50.672 82.665 -14.909 1.00 25.28 ? 539 SER A CB 1 ATOM 4373 O OG . SER A 1 539 ? 50.092 81.751 -15.864 1.00 31.10 ? 539 SER A OG 1 ATOM 4374 N N . ARG A 1 540 ? 51.970 83.437 -17.875 1.00 23.12 ? 540 ARG A N 1 ATOM 4375 C CA . ARG A 1 540 ? 52.914 82.932 -18.851 1.00 22.78 ? 540 ARG A CA 1 ATOM 4376 C C . ARG A 1 540 ? 53.939 83.928 -19.275 1.00 21.38 ? 540 ARG A C 1 ATOM 4377 O O . ARG A 1 540 ? 53.651 85.104 -19.404 1.00 26.69 ? 540 ARG A O 1 ATOM 4378 C CB . ARG A 1 540 ? 52.192 82.443 -20.090 1.00 24.20 ? 540 ARG A CB 1 ATOM 4379 C CG . ARG A 1 540 ? 51.253 81.245 -19.813 1.00 19.30 ? 540 ARG A CG 1 ATOM 4380 C CD . ARG A 1 540 ? 50.424 80.911 -21.061 1.00 17.06 ? 540 ARG A CD 1 ATOM 4381 N NE . ARG A 1 540 ? 51.241 80.267 -22.118 1.00 14.54 ? 540 ARG A NE 1 ATOM 4382 C CZ . ARG A 1 540 ? 50.791 79.879 -23.311 1.00 15.02 ? 540 ARG A CZ 1 ATOM 4383 N NH1 . ARG A 1 540 ? 49.526 80.037 -23.701 1.00 17.96 ? 540 ARG A NH1 1 ATOM 4384 N NH2 . ARG A 1 540 ? 51.638 79.293 -24.135 1.00 16.73 ? 540 ARG A NH2 1 ATOM 4385 N N . THR A 1 541 ? 55.136 83.436 -19.446 1.00 20.13 ? 541 THR A N 1 ATOM 4386 C CA . THR A 1 541 ? 56.156 84.336 -19.891 1.00 21.17 ? 541 THR A CA 1 ATOM 4387 C C . THR A 1 541 ? 56.178 84.387 -21.433 1.00 19.52 ? 541 THR A C 1 ATOM 4388 O O . THR A 1 541 ? 55.934 83.405 -22.133 1.00 24.52 ? 541 THR A O 1 ATOM 4389 C CB . THR A 1 541 ? 57.495 83.862 -19.422 1.00 25.10 ? 541 THR A CB 1 ATOM 4390 O OG1 . THR A 1 541 ? 57.824 82.723 -20.187 1.00 30.93 ? 541 THR A OG1 1 ATOM 4391 C CG2 . THR A 1 541 ? 57.453 83.453 -17.944 1.00 22.54 ? 541 THR A CG2 1 ATOM 4392 N N . THR A 1 542 ? 56.481 85.566 -21.945 1.00 17.38 ? 542 THR A N 1 ATOM 4393 C CA . THR A 1 542 ? 56.625 85.750 -23.374 1.00 14.52 ? 542 THR A CA 1 ATOM 4394 C C . THR A 1 542 ? 58.087 85.503 -23.704 1.00 12.76 ? 542 THR A C 1 ATOM 4395 O O . THR A 1 542 ? 58.988 85.947 -22.953 1.00 15.60 ? 542 THR A O 1 ATOM 4396 C CB . THR A 1 542 ? 56.285 87.203 -23.766 1.00 15.80 ? 542 THR A CB 1 ATOM 4397 O OG1 . THR A 1 542 ? 54.928 87.468 -23.408 1.00 17.81 ? 542 THR A OG1 1 ATOM 4398 C CG2 . THR A 1 542 ? 56.450 87.436 -25.250 1.00 15.14 ? 542 THR A CG2 1 ATOM 4399 N N . ILE A 1 543 ? 58.320 84.741 -24.754 1.00 11.41 ? 543 ILE A N 1 ATOM 4400 C CA . ILE A 1 543 ? 59.704 84.536 -25.245 1.00 12.07 ? 543 ILE A CA 1 ATOM 4401 C C . ILE A 1 543 ? 60.048 85.844 -26.035 1.00 11.54 ? 543 ILE A C 1 ATOM 4402 O O . ILE A 1 543 ? 59.402 86.130 -27.060 1.00 13.15 ? 543 ILE A O 1 ATOM 4403 C CB . ILE A 1 543 ? 59.763 83.315 -26.135 1.00 12.60 ? 543 ILE A CB 1 ATOM 4404 C CG1 . ILE A 1 543 ? 59.433 82.058 -25.267 1.00 13.56 ? 543 ILE A CG1 1 ATOM 4405 C CG2 . ILE A 1 543 ? 61.109 83.223 -26.867 1.00 13.04 ? 543 ILE A CG2 1 ATOM 4406 C CD1 . ILE A 1 543 ? 59.325 80.754 -26.065 1.00 12.46 ? 543 ILE A CD1 1 ATOM 4407 N N . ILE A 1 544 ? 60.993 86.593 -25.489 1.00 13.08 ? 544 ILE A N 1 ATOM 4408 C CA . ILE A 1 544 ? 61.384 87.877 -26.067 1.00 12.00 ? 544 ILE A CA 1 ATOM 4409 C C . ILE A 1 544 ? 62.614 87.720 -26.980 1.00 13.61 ? 544 ILE A C 1 ATOM 4410 O O . ILE A 1 544 ? 63.733 87.383 -26.538 1.00 14.69 ? 544 ILE A O 1 ATOM 4411 C CB . ILE A 1 544 ? 61.585 88.908 -24.938 1.00 15.17 ? 544 ILE A CB 1 ATOM 4412 C CG1 . ILE A 1 544 ? 60.236 89.053 -24.194 1.00 18.39 ? 544 ILE A CG1 1 ATOM 4413 C CG2 . ILE A 1 544 ? 62.044 90.261 -25.549 1.00 18.37 ? 544 ILE A CG2 1 ATOM 4414 C CD1 . ILE A 1 544 ? 60.131 90.142 -23.156 1.00 24.23 ? 544 ILE A CD1 1 ATOM 4415 N N . LEU A 1 545 ? 62.342 87.917 -28.268 1.00 12.37 ? 545 LEU A N 1 ATOM 4416 C CA . LEU A 1 545 ? 63.371 87.790 -29.289 1.00 11.86 ? 545 LEU A CA 1 ATOM 4417 C C . LEU A 1 545 ? 63.499 89.144 -29.995 1.00 14.71 ? 545 LEU A C 1 ATOM 4418 O O . LEU A 1 545 ? 62.583 89.963 -30.002 1.00 16.31 ? 545 LEU A O 1 ATOM 4419 C CB . LEU A 1 545 ? 62.971 86.690 -30.295 1.00 11.80 ? 545 LEU A CB 1 ATOM 4420 C CG . LEU A 1 545 ? 62.739 85.268 -29.700 1.00 12.15 ? 545 LEU A CG 1 ATOM 4421 C CD1 . LEU A 1 545 ? 62.291 84.305 -30.836 1.00 16.74 ? 545 LEU A CD1 1 ATOM 4422 C CD2 . LEU A 1 545 ? 64.048 84.767 -29.082 1.00 13.01 ? 545 LEU A CD2 1 ATOM 4423 N N . GLY A 1 546 ? 64.650 89.388 -30.587 1.00 14.54 ? 546 GLY A N 1 ATOM 4424 C CA . GLY A 1 546 ? 64.835 90.644 -31.307 1.00 15.78 ? 546 GLY A CA 1 ATOM 4425 C C . GLY A 1 546 ? 66.270 90.657 -31.758 1.00 13.80 ? 546 GLY A C 1 ATOM 4426 O O . GLY A 1 546 ? 67.197 90.183 -31.082 1.00 14.68 ? 546 GLY A O 1 ATOM 4427 N N . GLU A 1 547 ? 66.465 91.290 -32.913 1.00 17.05 ? 547 GLU A N 1 ATOM 4428 C CA . GLU A 1 547 ? 67.809 91.403 -33.505 1.00 20.81 ? 547 GLU A CA 1 ATOM 4429 C C . GLU A 1 547 ? 68.827 92.084 -32.568 1.00 22.13 ? 547 GLU A C 1 ATOM 4430 O O . GLU A 1 547 ? 70.020 91.732 -32.525 1.00 23.83 ? 547 GLU A O 1 ATOM 4431 C CB . GLU A 1 547 ? 67.732 92.178 -34.824 1.00 26.57 ? 547 GLU A CB 1 ATOM 4432 C CG . GLU A 1 547 ? 69.086 92.268 -35.543 1.00 39.14 ? 547 GLU A CG 1 ATOM 4433 C CD . GLU A 1 547 ? 69.102 93.311 -36.683 1.00 45.35 ? 547 GLU A CD 1 ATOM 4434 O OE1 . GLU A 1 547 ? 68.025 93.895 -36.994 1.00 47.76 ? 547 GLU A OE1 1 ATOM 4435 O OE2 . GLU A 1 547 ? 70.202 93.537 -37.263 1.00 49.00 ? 547 GLU A OE2 1 ATOM 4436 N N . ASP A 1 548 ? 68.332 93.018 -31.767 1.00 17.05 ? 548 ASP A N 1 ATOM 4437 C CA . ASP A 1 548 ? 69.194 93.717 -30.836 1.00 19.38 ? 548 ASP A CA 1 ATOM 4438 C C . ASP A 1 548 ? 69.160 93.144 -29.437 1.00 20.96 ? 548 ASP A C 1 ATOM 4439 O O . ASP A 1 548 ? 69.598 93.813 -28.505 1.00 23.42 ? 548 ASP A O 1 ATOM 4440 C CB . ASP A 1 548 ? 68.800 95.195 -30.772 1.00 19.95 ? 548 ASP A CB 1 ATOM 4441 C CG . ASP A 1 548 ? 69.000 95.894 -32.085 1.00 25.25 ? 548 ASP A CG 1 ATOM 4442 O OD1 . ASP A 1 548 ? 70.172 95.981 -32.527 1.00 28.88 ? 548 ASP A OD1 1 ATOM 4443 O OD2 . ASP A 1 548 ? 68.006 96.356 -32.682 1.00 29.28 ? 548 ASP A OD2 1 ATOM 4444 N N . ILE A 1 549 ? 68.644 91.926 -29.244 1.00 17.12 ? 549 ILE A N 1 ATOM 4445 C CA . ILE A 1 549 ? 68.625 91.377 -27.872 1.00 17.59 ? 549 ILE A CA 1 ATOM 4446 C C . ILE A 1 549 ? 68.870 89.852 -27.818 1.00 19.09 ? 549 ILE A C 1 ATOM 4447 O O . ILE A 1 549 ? 69.703 89.403 -27.024 1.00 18.99 ? 549 ILE A O 1 ATOM 4448 C CB . ILE A 1 549 ? 67.265 91.730 -27.106 1.00 17.73 ? 549 ILE A CB 1 ATOM 4449 C CG1 . ILE A 1 549 ? 67.262 91.103 -25.696 1.00 22.60 ? 549 ILE A CG1 1 ATOM 4450 C CG2 . ILE A 1 549 ? 66.027 91.251 -27.852 1.00 17.32 ? 549 ILE A CG2 1 ATOM 4451 C CD1 . ILE A 1 549 ? 67.972 91.930 -24.698 1.00 29.37 ? 549 ILE A CD1 1 ATOM 4452 N N . LEU A 1 550 ? 68.186 89.093 -28.680 1.00 15.06 ? 550 LEU A N 1 ATOM 4453 C CA . LEU A 1 550 ? 68.311 87.643 -28.597 1.00 14.04 ? 550 LEU A CA 1 ATOM 4454 C C . LEU A 1 550 ? 67.676 87.071 -29.846 1.00 13.53 ? 550 LEU A C 1 ATOM 4455 O O . LEU A 1 550 ? 66.477 87.199 -30.086 1.00 15.34 ? 550 LEU A O 1 ATOM 4456 C CB . LEU A 1 550 ? 67.563 87.145 -27.345 1.00 16.31 ? 550 LEU A CB 1 ATOM 4457 C CG . LEU A 1 550 ? 67.613 85.623 -27.169 1.00 16.14 ? 550 LEU A CG 1 ATOM 4458 C CD1 . LEU A 1 550 ? 69.046 85.261 -26.936 1.00 16.86 ? 550 LEU A CD1 1 ATOM 4459 C CD2 . LEU A 1 550 ? 66.759 85.167 -26.006 1.00 17.10 ? 550 LEU A CD2 1 ATOM 4460 N N . PRO A 1 551 ? 68.463 86.402 -30.689 1.00 13.49 ? 551 PRO A N 1 ATOM 4461 C CA . PRO A 1 551 ? 67.826 85.896 -31.896 1.00 14.88 ? 551 PRO A CA 1 ATOM 4462 C C . PRO A 1 551 ? 67.002 84.603 -31.800 1.00 13.20 ? 551 PRO A C 1 ATOM 4463 O O . PRO A 1 551 ? 66.159 84.365 -32.666 1.00 14.68 ? 551 PRO A O 1 ATOM 4464 C CB . PRO A 1 551 ? 68.992 85.718 -32.890 1.00 18.28 ? 551 PRO A CB 1 ATOM 4465 C CG . PRO A 1 551 ? 70.119 85.545 -32.121 1.00 21.07 ? 551 PRO A CG 1 ATOM 4466 C CD . PRO A 1 551 ? 69.928 86.397 -30.830 1.00 17.19 ? 551 PRO A CD 1 ATOM 4467 N N . SER A 1 552 ? 67.293 83.781 -30.783 1.00 12.12 ? 552 SER A N 1 ATOM 4468 C CA . SER A 1 552 ? 66.602 82.477 -30.722 1.00 11.51 ? 552 SER A CA 1 ATOM 4469 C C . SER A 1 552 ? 66.507 81.986 -29.283 1.00 10.48 ? 552 SER A C 1 ATOM 4470 O O . SER A 1 552 ? 67.147 82.494 -28.401 1.00 11.80 ? 552 SER A O 1 ATOM 4471 C CB . SER A 1 552 ? 67.313 81.441 -31.569 1.00 12.34 ? 552 SER A CB 1 ATOM 4472 O OG . SER A 1 552 ? 68.541 81.073 -31.011 1.00 15.63 ? 552 SER A OG 1 ATOM 4473 N N . LYS A 1 553 ? 65.608 81.001 -29.123 1.00 11.61 ? 553 LYS A N 1 ATOM 4474 C CA . LYS A 1 553 ? 65.332 80.421 -27.820 1.00 10.12 ? 553 LYS A CA 1 ATOM 4475 C C . LYS A 1 553 ? 65.060 78.896 -27.947 1.00 10.20 ? 553 LYS A C 1 ATOM 4476 O O . LYS A 1 553 ? 64.262 78.471 -28.785 1.00 10.69 ? 553 LYS A O 1 ATOM 4477 C CB . LYS A 1 553 ? 64.033 81.066 -27.250 1.00 11.45 ? 553 LYS A CB 1 ATOM 4478 C CG . LYS A 1 553 ? 63.563 80.518 -25.861 1.00 12.62 ? 553 LYS A CG 1 ATOM 4479 C CD . LYS A 1 553 ? 64.621 80.636 -24.848 1.00 13.02 ? 553 LYS A CD 1 ATOM 4480 C CE . LYS A 1 553 ? 64.808 82.095 -24.393 1.00 13.31 ? 553 LYS A CE 1 ATOM 4481 N NZ . LYS A 1 553 ? 66.048 82.174 -23.473 1.00 15.04 ? 553 LYS A NZ 1 ATOM 4482 N N . HIS A 1 554 ? 65.731 78.133 -27.081 1.00 9.59 ? 554 HIS A N 1 ATOM 4483 C CA . HIS A 1 554 ? 65.431 76.697 -26.953 1.00 9.44 ? 554 HIS A CA 1 ATOM 4484 C C . HIS A 1 554 ? 64.209 76.466 -26.030 1.00 8.49 ? 554 HIS A C 1 ATOM 4485 O O . HIS A 1 554 ? 64.085 77.089 -24.974 1.00 10.46 ? 554 HIS A O 1 ATOM 4486 C CB . HIS A 1 554 ? 66.658 75.943 -26.367 1.00 11.45 ? 554 HIS A CB 1 ATOM 4487 C CG . HIS A 1 554 ? 67.781 75.816 -27.350 1.00 12.97 ? 554 HIS A CG 1 ATOM 4488 N ND1 . HIS A 1 554 ? 68.486 74.658 -27.612 1.00 19.88 ? 554 HIS A ND1 1 ATOM 4489 C CD2 . HIS A 1 554 ? 68.340 76.778 -28.136 1.00 15.94 ? 554 HIS A CD2 1 ATOM 4490 C CE1 . HIS A 1 554 ? 69.442 74.922 -28.493 1.00 14.80 ? 554 HIS A CE1 1 ATOM 4491 N NE2 . HIS A 1 554 ? 69.370 76.197 -28.824 1.00 23.87 ? 554 HIS A NE2 1 ATOM 4492 N N . VAL A 1 555 ? 63.355 75.540 -26.477 1.00 8.98 ? 555 VAL A N 1 ATOM 4493 C CA . VAL A 1 555 ? 62.221 75.056 -25.686 1.00 9.79 ? 555 VAL A CA 1 ATOM 4494 C C . VAL A 1 555 ? 62.302 73.532 -25.662 1.00 9.16 ? 555 VAL A C 1 ATOM 4495 O O . VAL A 1 555 ? 62.859 72.904 -26.589 1.00 9.93 ? 555 VAL A O 1 ATOM 4496 C CB . VAL A 1 555 ? 60.877 75.524 -26.225 1.00 9.08 ? 555 VAL A CB 1 ATOM 4497 C CG1 . VAL A 1 555 ? 60.819 77.042 -26.151 1.00 10.64 ? 555 VAL A CG1 1 ATOM 4498 C CG2 . VAL A 1 555 ? 60.647 75.035 -27.624 1.00 10.84 ? 555 VAL A CG2 1 ATOM 4499 N N . VAL A 1 556 ? 61.764 72.918 -24.600 1.00 8.05 ? 556 VAL A N 1 ATOM 4500 C CA . VAL A 1 556 ? 61.821 71.453 -24.468 1.00 8.63 ? 556 VAL A CA 1 ATOM 4501 C C . VAL A 1 556 ? 60.430 70.949 -24.069 1.00 8.28 ? 556 VAL A C 1 ATOM 4502 O O . VAL A 1 556 ? 59.790 71.542 -23.168 1.00 8.41 ? 556 VAL A O 1 ATOM 4503 C CB . VAL A 1 556 ? 62.832 71.031 -23.354 1.00 8.72 ? 556 VAL A CB 1 ATOM 4504 C CG1 . VAL A 1 556 ? 62.776 69.498 -23.131 1.00 8.85 ? 556 VAL A CG1 1 ATOM 4505 C CG2 . VAL A 1 556 ? 64.255 71.446 -23.743 1.00 10.54 ? 556 VAL A CG2 1 ATOM 4506 N N . MET A 1 557 ? 60.006 69.866 -24.697 1.00 7.56 ? 557 MET A N 1 ATOM 4507 C CA . MET A 1 557 ? 58.741 69.207 -24.316 1.00 8.50 ? 557 MET A CA 1 ATOM 4508 C C . MET A 1 557 ? 59.016 67.879 -23.646 1.00 8.15 ? 557 MET A C 1 ATOM 4509 O O . MET A 1 557 ? 59.917 67.136 -24.071 1.00 8.63 ? 557 MET A O 1 ATOM 4510 C CB . MET A 1 557 ? 57.843 68.936 -25.526 1.00 8.34 ? 557 MET A CB 1 ATOM 4511 C CG . MET A 1 557 ? 56.843 70.057 -25.820 1.00 9.85 ? 557 MET A CG 1 ATOM 4512 S SD . MET A 1 557 ? 57.514 71.730 -26.009 1.00 10.72 ? 557 MET A SD 1 ATOM 4513 C CE . MET A 1 557 ? 58.567 71.481 -27.477 1.00 13.58 ? 557 MET A CE 1 ATOM 4514 N N . HIS A 1 558 ? 58.242 67.564 -22.595 1.00 7.69 ? 558 HIS A N 1 ATOM 4515 C CA . HIS A 1 558 ? 58.306 66.254 -21.930 1.00 6.40 ? 558 HIS A CA 1 ATOM 4516 C C . HIS A 1 558 ? 57.009 65.507 -22.173 1.00 8.37 ? 558 HIS A C 1 ATOM 4517 O O . HIS A 1 558 ? 55.908 66.109 -22.160 1.00 8.67 ? 558 HIS A O 1 ATOM 4518 C CB . HIS A 1 558 ? 58.489 66.442 -20.443 1.00 8.43 ? 558 HIS A CB 1 ATOM 4519 C CG . HIS A 1 558 ? 58.402 65.161 -19.657 1.00 7.16 ? 558 HIS A CG 1 ATOM 4520 N ND1 . HIS A 1 558 ? 57.463 65.006 -18.654 1.00 7.89 ? 558 HIS A ND1 1 ATOM 4521 C CD2 . HIS A 1 558 ? 59.144 64.017 -19.664 1.00 7.47 ? 558 HIS A CD2 1 ATOM 4522 C CE1 . HIS A 1 558 ? 57.655 63.817 -18.083 1.00 8.05 ? 558 HIS A CE1 1 ATOM 4523 N NE2 . HIS A 1 558 ? 58.665 63.190 -18.667 1.00 9.32 ? 558 HIS A NE2 1 ATOM 4524 N N . ASN A 1 559 ? 57.131 64.181 -22.379 1.00 7.21 ? 559 ASN A N 1 ATOM 4525 C CA . ASN A 1 559 ? 55.986 63.327 -22.572 1.00 6.44 ? 559 ASN A CA 1 ATOM 4526 C C . ASN A 1 559 ? 56.004 62.235 -21.502 1.00 6.80 ? 559 ASN A C 1 ATOM 4527 O O . ASN A 1 559 ? 56.760 61.266 -21.630 1.00 8.77 ? 559 ASN A O 1 ATOM 4528 C CB . ASN A 1 559 ? 56.086 62.694 -23.964 1.00 7.78 ? 559 ASN A CB 1 ATOM 4529 C CG . ASN A 1 559 ? 55.048 61.588 -24.174 1.00 8.13 ? 559 ASN A CG 1 ATOM 4530 O OD1 . ASN A 1 559 ? 53.945 61.576 -23.601 1.00 9.38 ? 559 ASN A OD1 1 ATOM 4531 N ND2 . ASN A 1 559 ? 55.388 60.624 -25.051 1.00 9.28 ? 559 ASN A ND2 1 ATOM 4532 N N . THR A 1 560 ? 55.133 62.340 -20.492 1.00 7.37 ? 560 THR A N 1 ATOM 4533 C CA . THR A 1 560 ? 55.152 61.352 -19.395 1.00 6.99 ? 560 THR A CA 1 ATOM 4534 C C . THR A 1 560 ? 54.558 60.003 -19.820 1.00 8.14 ? 560 THR A C 1 ATOM 4535 O O . THR A 1 560 ? 54.744 59.028 -19.102 1.00 8.03 ? 560 THR A O 1 ATOM 4536 C CB . THR A 1 560 ? 54.393 61.965 -18.205 1.00 6.96 ? 560 THR A CB 1 ATOM 4537 O OG1 . THR A 1 560 ? 54.690 61.214 -17.006 1.00 8.10 ? 560 THR A OG1 1 ATOM 4538 C CG2 . THR A 1 560 ? 52.877 62.004 -18.371 1.00 8.30 ? 560 THR A CG2 1 ATOM 4539 N N . LEU A 1 561 ? 53.823 59.931 -20.921 1.00 8.27 ? 561 LEU A N 1 ATOM 4540 C CA . LEU A 1 561 ? 53.216 58.649 -21.337 1.00 7.06 ? 561 LEU A CA 1 ATOM 4541 C C . LEU A 1 561 ? 54.230 57.748 -22.018 1.00 7.84 ? 561 LEU A C 1 ATOM 4542 O O . LEU A 1 561 ? 55.135 58.209 -22.727 1.00 8.56 ? 561 LEU A O 1 ATOM 4543 C CB . LEU A 1 561 ? 52.064 58.942 -22.307 1.00 8.88 ? 561 LEU A CB 1 ATOM 4544 C CG . LEU A 1 561 ? 50.964 59.881 -21.753 1.00 8.94 ? 561 LEU A CG 1 ATOM 4545 C CD1 . LEU A 1 561 ? 49.847 60.034 -22.842 1.00 11.45 ? 561 LEU A CD1 1 ATOM 4546 C CD2 . LEU A 1 561 ? 50.269 59.286 -20.506 1.00 9.68 ? 561 LEU A CD2 1 ATOM 4547 N N . PRO A 1 562 ? 54.085 56.431 -21.850 1.00 8.21 ? 562 PRO A N 1 ATOM 4548 C CA . PRO A 1 562 ? 55.040 55.469 -22.434 1.00 8.10 ? 562 PRO A CA 1 ATOM 4549 C C . PRO A 1 562 ? 54.838 55.104 -23.885 1.00 8.96 ? 562 PRO A C 1 ATOM 4550 O O . PRO A 1 562 ? 55.002 53.943 -24.266 1.00 10.53 ? 562 PRO A O 1 ATOM 4551 C CB . PRO A 1 562 ? 54.883 54.277 -21.487 1.00 9.24 ? 562 PRO A CB 1 ATOM 4552 C CG . PRO A 1 562 ? 53.399 54.273 -21.180 1.00 8.85 ? 562 PRO A CG 1 ATOM 4553 C CD . PRO A 1 562 ? 53.102 55.764 -20.964 1.00 8.45 ? 562 PRO A CD 1 ATOM 4554 N N . HIS A 1 563 ? 54.489 56.071 -24.715 1.00 8.70 ? 563 HIS A N 1 ATOM 4555 C CA . HIS A 1 563 ? 54.436 55.815 -26.158 1.00 9.27 ? 563 HIS A CA 1 ATOM 4556 C C . HIS A 1 563 ? 54.829 57.122 -26.825 1.00 9.64 ? 563 HIS A C 1 ATOM 4557 O O . HIS A 1 563 ? 54.649 58.224 -26.244 1.00 9.51 ? 563 HIS A O 1 ATOM 4558 C CB . HIS A 1 563 ? 53.033 55.349 -26.632 1.00 10.02 ? 563 HIS A CB 1 ATOM 4559 C CG . HIS A 1 563 ? 51.890 56.220 -26.181 1.00 10.23 ? 563 HIS A CG 1 ATOM 4560 N ND1 . HIS A 1 563 ? 51.085 55.894 -25.101 1.00 10.55 ? 563 HIS A ND1 1 ATOM 4561 C CD2 . HIS A 1 563 ? 51.392 57.390 -26.673 1.00 10.82 ? 563 HIS A CD2 1 ATOM 4562 C CE1 . HIS A 1 563 ? 50.134 56.810 -24.960 1.00 11.77 ? 563 HIS A CE1 1 ATOM 4563 N NE2 . HIS A 1 563 ? 50.302 57.735 -25.895 1.00 11.60 ? 563 HIS A NE2 1 ATOM 4564 N N . TRP A 1 564 ? 55.343 57.040 -28.043 1.00 9.90 ? 564 TRP A N 1 ATOM 4565 C CA . TRP A 1 564 ? 55.641 58.232 -28.838 1.00 8.71 ? 564 TRP A CA 1 ATOM 4566 C C . TRP A 1 564 ? 54.372 59.058 -28.963 1.00 10.02 ? 564 TRP A C 1 ATOM 4567 O O . TRP A 1 564 ? 53.236 58.546 -29.141 1.00 11.01 ? 564 TRP A O 1 ATOM 4568 C CB . TRP A 1 564 ? 56.091 57.864 -30.285 1.00 11.82 ? 564 TRP A CB 1 ATOM 4569 C CG . TRP A 1 564 ? 57.543 57.445 -30.350 1.00 10.25 ? 564 TRP A CG 1 ATOM 4570 C CD1 . TRP A 1 564 ? 58.045 56.146 -30.204 1.00 11.75 ? 564 TRP A CD1 1 ATOM 4571 C CD2 . TRP A 1 564 ? 58.683 58.295 -30.505 1.00 11.40 ? 564 TRP A CD2 1 ATOM 4572 N NE1 . TRP A 1 564 ? 59.384 56.192 -30.259 1.00 13.34 ? 564 TRP A NE1 1 ATOM 4573 C CE2 . TRP A 1 564 ? 59.833 57.478 -30.440 1.00 12.34 ? 564 TRP A CE2 1 ATOM 4574 C CE3 . TRP A 1 564 ? 58.838 59.682 -30.697 1.00 14.34 ? 564 TRP A CE3 1 ATOM 4575 C CZ2 . TRP A 1 564 ? 61.144 57.996 -30.555 1.00 14.56 ? 564 TRP A CZ2 1 ATOM 4576 C CZ3 . TRP A 1 564 ? 60.142 60.210 -30.808 1.00 13.89 ? 564 TRP A CZ3 1 ATOM 4577 C CH2 . TRP A 1 564 ? 61.278 59.364 -30.740 1.00 15.83 ? 564 TRP A CH2 1 ATOM 4578 N N . ARG A 1 565 ? 54.514 60.372 -28.868 1.00 9.95 ? 565 ARG A N 1 ATOM 4579 C CA . ARG A 1 565 ? 53.305 61.174 -28.927 1.00 10.37 ? 565 ARG A CA 1 ATOM 4580 C C . ARG A 1 565 ? 53.572 62.472 -29.669 1.00 10.20 ? 565 ARG A C 1 ATOM 4581 O O . ARG A 1 565 ? 54.596 63.126 -29.421 1.00 11.23 ? 565 ARG A O 1 ATOM 4582 C CB . ARG A 1 565 ? 52.790 61.503 -27.477 1.00 11.65 ? 565 ARG A CB 1 ATOM 4583 C CG . ARG A 1 565 ? 51.476 62.342 -27.504 1.00 13.42 ? 565 ARG A CG 1 ATOM 4584 C CD . ARG A 1 565 ? 50.612 62.273 -26.175 1.00 15.05 ? 565 ARG A CD 1 ATOM 4585 N NE . ARG A 1 565 ? 51.398 62.572 -24.991 1.00 15.00 ? 565 ARG A NE 1 ATOM 4586 C CZ . ARG A 1 565 ? 50.898 63.144 -23.902 1.00 11.80 ? 565 ARG A CZ 1 ATOM 4587 N NH1 . ARG A 1 565 ? 49.609 63.525 -23.838 1.00 12.25 ? 565 ARG A NH1 1 ATOM 4588 N NH2 . ARG A 1 565 ? 51.699 63.278 -22.876 1.00 11.54 ? 565 ARG A NH2 1 ATOM 4589 N N . GLU A 1 566 ? 52.633 62.836 -30.535 1.00 10.92 ? 566 GLU A N 1 ATOM 4590 C CA . GLU A 1 566 ? 52.647 64.184 -31.138 1.00 11.65 ? 566 GLU A CA 1 ATOM 4591 C C . GLU A 1 566 ? 51.498 64.982 -30.537 1.00 11.99 ? 566 GLU A C 1 ATOM 4592 O O . GLU A 1 566 ? 50.407 64.451 -30.261 1.00 13.00 ? 566 GLU A O 1 ATOM 4593 C CB . GLU A 1 566 ? 52.419 64.093 -32.633 1.00 14.37 ? 566 GLU A CB 1 ATOM 4594 C CG . GLU A 1 566 ? 53.530 63.479 -33.352 1.00 14.65 ? 566 GLU A CG 1 ATOM 4595 C CD . GLU A 1 566 ? 53.251 63.426 -34.872 1.00 18.78 ? 566 GLU A CD 1 ATOM 4596 O OE1 . GLU A 1 566 ? 52.069 63.231 -35.281 1.00 21.95 ? 566 GLU A OE1 1 ATOM 4597 O OE2 . GLU A 1 566 ? 54.230 63.619 -35.610 1.00 22.91 ? 566 GLU A OE2 1 ATOM 4598 N N . GLN A 1 567 ? 51.722 66.278 -30.348 1.00 11.22 ? 567 GLN A N 1 ATOM 4599 C CA . GLN A 1 567 ? 50.681 67.169 -29.832 1.00 10.09 ? 567 GLN A CA 1 ATOM 4600 C C . GLN A 1 567 ? 51.086 68.574 -30.242 1.00 11.14 ? 567 GLN A C 1 ATOM 4601 O O . GLN A 1 567 ? 52.297 68.919 -30.285 1.00 10.13 ? 567 GLN A O 1 ATOM 4602 C CB . GLN A 1 567 ? 50.642 67.115 -28.282 1.00 11.37 ? 567 GLN A CB 1 ATOM 4603 C CG . GLN A 1 567 ? 49.516 67.911 -27.655 1.00 11.49 ? 567 GLN A CG 1 ATOM 4604 C CD . GLN A 1 567 ? 49.896 68.360 -26.254 1.00 13.52 ? 567 GLN A CD 1 ATOM 4605 O OE1 . GLN A 1 567 ? 49.906 67.547 -25.315 1.00 12.79 ? 567 GLN A OE1 1 ATOM 4606 N NE2 . GLN A 1 567 ? 50.307 69.633 -26.101 1.00 16.94 ? 567 GLN A NE2 1 ATOM 4607 N N . LEU A 1 568 ? 50.086 69.369 -30.601 1.00 11.02 ? 568 LEU A N 1 ATOM 4608 C CA . LEU A 1 568 ? 50.409 70.788 -30.857 1.00 10.60 ? 568 LEU A CA 1 ATOM 4609 C C . LEU A 1 568 ? 50.744 71.473 -29.539 1.00 10.42 ? 568 LEU A C 1 ATOM 4610 O O . LEU A 1 568 ? 50.070 71.225 -28.497 1.00 11.32 ? 568 LEU A O 1 ATOM 4611 C CB . LEU A 1 568 ? 49.239 71.585 -31.478 1.00 12.35 ? 568 LEU A CB 1 ATOM 4612 C CG . LEU A 1 568 ? 48.778 71.104 -32.858 1.00 14.00 ? 568 LEU A CG 1 ATOM 4613 C CD1 . LEU A 1 568 ? 47.811 72.168 -33.442 1.00 15.39 ? 568 LEU A CD1 1 ATOM 4614 C CD2 . LEU A 1 568 ? 49.955 70.975 -33.799 1.00 16.12 ? 568 LEU A CD2 1 ATOM 4615 N N . VAL A 1 569 ? 51.743 72.315 -29.564 1.00 9.02 ? 569 VAL A N 1 ATOM 4616 C CA . VAL A 1 569 ? 52.134 73.101 -28.412 1.00 9.25 ? 569 VAL A CA 1 ATOM 4617 C C . VAL A 1 569 ? 52.195 74.572 -28.833 1.00 9.41 ? 569 VAL A C 1 ATOM 4618 O O . VAL A 1 569 ? 52.431 74.896 -29.998 1.00 11.07 ? 569 VAL A O 1 ATOM 4619 C CB . VAL A 1 569 ? 53.510 72.670 -27.824 1.00 9.25 ? 569 VAL A CB 1 ATOM 4620 C CG1 . VAL A 1 569 ? 53.371 71.270 -27.159 1.00 11.06 ? 569 VAL A CG1 1 ATOM 4621 C CG2 . VAL A 1 569 ? 54.639 72.687 -28.895 1.00 11.40 ? 569 VAL A CG2 1 ATOM 4622 N N . ASP A 1 570 ? 51.956 75.455 -27.882 1.00 9.73 ? 570 ASP A N 1 ATOM 4623 C CA . ASP A 1 570 ? 52.014 76.881 -28.220 1.00 9.82 ? 570 ASP A CA 1 ATOM 4624 C C . ASP A 1 570 ? 52.813 77.629 -27.198 1.00 10.93 ? 570 ASP A C 1 ATOM 4625 O O . ASP A 1 570 ? 52.912 77.243 -26.008 1.00 13.16 ? 570 ASP A O 1 ATOM 4626 C CB . ASP A 1 570 ? 50.592 77.478 -28.357 1.00 11.94 ? 570 ASP A CB 1 ATOM 4627 C CG . ASP A 1 570 ? 49.881 77.610 -27.037 1.00 19.59 ? 570 ASP A CG 1 ATOM 4628 O OD1 . ASP A 1 570 ? 49.723 76.603 -26.356 1.00 26.61 ? 570 ASP A OD1 1 ATOM 4629 O OD2 . ASP A 1 570 ? 49.498 78.709 -26.612 1.00 26.44 ? 570 ASP A OD2 1 ATOM 4630 N N . PHE A 1 571 ? 53.440 78.716 -27.661 1.00 10.30 ? 571 PHE A N 1 ATOM 4631 C CA . PHE A 1 571 ? 54.223 79.603 -26.796 1.00 10.42 ? 571 PHE A CA 1 ATOM 4632 C C . PHE A 1 571 ? 53.870 81.052 -27.185 1.00 9.81 ? 571 PHE A C 1 ATOM 4633 O O . PHE A 1 571 ? 53.552 81.307 -28.339 1.00 12.25 ? 571 PHE A O 1 ATOM 4634 C CB . PHE A 1 571 ? 55.741 79.425 -27.062 1.00 11.06 ? 571 PHE A CB 1 ATOM 4635 C CG . PHE A 1 571 ? 56.282 78.073 -26.643 1.00 9.32 ? 571 PHE A CG 1 ATOM 4636 C CD1 . PHE A 1 571 ? 56.254 77.007 -27.500 1.00 9.89 ? 571 PHE A CD1 1 ATOM 4637 C CD2 . PHE A 1 571 ? 56.737 77.907 -25.358 1.00 10.90 ? 571 PHE A CD2 1 ATOM 4638 C CE1 . PHE A 1 571 ? 56.680 75.727 -27.089 1.00 10.57 ? 571 PHE A CE1 1 ATOM 4639 C CE2 . PHE A 1 571 ? 57.162 76.650 -24.913 1.00 11.11 ? 571 PHE A CE2 1 ATOM 4640 C CZ . PHE A 1 571 ? 57.141 75.566 -25.788 1.00 11.36 ? 571 PHE A CZ 1 ATOM 4641 N N . TYR A 1 572 ? 54.001 81.969 -26.241 1.00 9.80 ? 572 TYR A N 1 ATOM 4642 C CA . TYR A 1 572 ? 53.866 83.400 -26.540 1.00 10.17 ? 572 TYR A CA 1 ATOM 4643 C C . TYR A 1 572 ? 55.263 83.887 -26.939 1.00 11.10 ? 572 TYR A C 1 ATOM 4644 O O . TYR A 1 572 ? 56.272 83.569 -26.278 1.00 11.20 ? 572 TYR A O 1 ATOM 4645 C CB . TYR A 1 572 ? 53.453 84.186 -25.299 1.00 11.91 ? 572 TYR A CB 1 ATOM 4646 C CG . TYR A 1 572 ? 52.032 84.020 -24.842 1.00 16.06 ? 572 TYR A CG 1 ATOM 4647 C CD1 . TYR A 1 572 ? 51.065 83.437 -25.643 1.00 16.81 ? 572 TYR A CD1 1 ATOM 4648 C CD2 . TYR A 1 572 ? 51.651 84.515 -23.593 1.00 23.05 ? 572 TYR A CD2 1 ATOM 4649 C CE1 . TYR A 1 572 ? 49.710 83.343 -25.225 1.00 17.69 ? 572 TYR A CE1 1 ATOM 4650 C CE2 . TYR A 1 572 ? 50.324 84.437 -23.173 1.00 22.17 ? 572 TYR A CE2 1 ATOM 4651 C CZ . TYR A 1 572 ? 49.366 83.857 -23.991 1.00 20.68 ? 572 TYR A CZ 1 ATOM 4652 O OH . TYR A 1 572 ? 48.038 83.803 -23.577 1.00 21.21 ? 572 TYR A OH 1 ATOM 4653 N N . VAL A 1 573 ? 55.288 84.675 -28.015 1.00 11.33 ? 573 VAL A N 1 ATOM 4654 C CA . VAL A 1 573 ? 56.536 85.252 -28.563 1.00 10.62 ? 573 VAL A CA 1 ATOM 4655 C C . VAL A 1 573 ? 56.297 86.740 -28.823 1.00 10.69 ? 573 VAL A C 1 ATOM 4656 O O . VAL A 1 573 ? 55.171 87.217 -29.077 1.00 12.56 ? 573 VAL A O 1 ATOM 4657 C CB . VAL A 1 573 ? 56.986 84.542 -29.857 1.00 12.02 ? 573 VAL A CB 1 ATOM 4658 C CG1 . VAL A 1 573 ? 57.526 83.133 -29.548 1.00 14.83 ? 573 VAL A CG1 1 ATOM 4659 C CG2 . VAL A 1 573 ? 55.870 84.457 -30.862 1.00 13.95 ? 573 VAL A CG2 1 ATOM 4660 N N . SER A 1 574 ? 57.402 87.485 -28.810 1.00 11.94 ? 574 SER A N 1 ATOM 4661 C CA . SER A 1 574 ? 57.299 88.968 -28.943 1.00 12.23 ? 574 SER A CA 1 ATOM 4662 C C . SER A 1 574 ? 57.277 89.466 -30.378 1.00 14.32 ? 574 SER A C 1 ATOM 4663 O O . SER A 1 574 ? 57.221 90.716 -30.580 1.00 18.22 ? 574 SER A O 1 ATOM 4664 C CB . SER A 1 574 ? 58.444 89.641 -28.195 1.00 14.73 ? 574 SER A CB 1 ATOM 4665 O OG . SER A 1 574 ? 59.696 89.293 -28.744 1.00 13.55 ? 574 SER A OG 1 ATOM 4666 N N . SER A 1 575 ? 57.309 88.567 -31.356 1.00 14.30 ? 575 SER A N 1 ATOM 4667 C CA . SER A 1 575 ? 57.225 88.917 -32.767 1.00 15.80 ? 575 SER A CA 1 ATOM 4668 C C . SER A 1 575 ? 56.456 87.845 -33.511 1.00 16.10 ? 575 SER A C 1 ATOM 4669 O O . SER A 1 575 ? 56.503 86.668 -33.133 1.00 14.85 ? 575 SER A O 1 ATOM 4670 C CB . SER A 1 575 ? 58.637 88.933 -33.382 1.00 18.13 ? 575 SER A CB 1 ATOM 4671 O OG . SER A 1 575 ? 58.619 88.990 -34.808 1.00 16.75 ? 575 SER A OG 1 ATOM 4672 N N . PRO A 1 576 ? 55.749 88.209 -34.573 1.00 15.72 ? 576 PRO A N 1 ATOM 4673 C CA . PRO A 1 576 ? 55.023 87.204 -35.346 1.00 13.37 ? 576 PRO A CA 1 ATOM 4674 C C . PRO A 1 576 ? 55.953 86.481 -36.349 1.00 13.45 ? 576 PRO A C 1 ATOM 4675 O O . PRO A 1 576 ? 55.586 85.485 -36.980 1.00 15.20 ? 576 PRO A O 1 ATOM 4676 C CB . PRO A 1 576 ? 53.915 88.030 -36.038 1.00 15.64 ? 576 PRO A CB 1 ATOM 4677 C CG . PRO A 1 576 ? 54.614 89.399 -36.219 1.00 20.26 ? 576 PRO A CG 1 ATOM 4678 C CD . PRO A 1 576 ? 55.474 89.595 -35.025 1.00 16.47 ? 576 PRO A CD 1 ATOM 4679 N N . PHE A 1 577 ? 57.164 87.017 -36.543 1.00 13.64 ? 577 PHE A N 1 ATOM 4680 C CA . PHE A 1 577 ? 58.077 86.461 -37.530 1.00 14.71 ? 577 PHE A CA 1 ATOM 4681 C C . PHE A 1 577 ? 59.054 85.512 -36.878 1.00 15.18 ? 577 PHE A C 1 ATOM 4682 O O . PHE A 1 577 ? 60.222 85.813 -36.659 1.00 15.91 ? 577 PHE A O 1 ATOM 4683 C CB . PHE A 1 577 ? 58.797 87.605 -38.260 1.00 15.06 ? 577 PHE A CB 1 ATOM 4684 C CG . PHE A 1 577 ? 57.838 88.598 -38.892 1.00 19.22 ? 577 PHE A CG 1 ATOM 4685 C CD1 . PHE A 1 577 ? 58.031 89.977 -38.680 1.00 22.93 ? 577 PHE A CD1 1 ATOM 4686 C CD2 . PHE A 1 577 ? 56.822 88.174 -39.720 1.00 17.36 ? 577 PHE A CD2 1 ATOM 4687 C CE1 . PHE A 1 577 ? 57.209 90.920 -39.305 1.00 24.17 ? 577 PHE A CE1 1 ATOM 4688 C CE2 . PHE A 1 577 ? 55.975 89.120 -40.366 1.00 20.13 ? 577 PHE A CE2 1 ATOM 4689 C CZ . PHE A 1 577 ? 56.199 90.488 -40.137 1.00 24.66 ? 577 PHE A CZ 1 ATOM 4690 N N . VAL A 1 578 ? 58.505 84.339 -36.552 1.00 12.70 ? 578 VAL A N 1 ATOM 4691 C CA . VAL A 1 578 ? 59.281 83.332 -35.834 1.00 14.04 ? 578 VAL A CA 1 ATOM 4692 C C . VAL A 1 578 ? 59.140 82.003 -36.523 1.00 12.66 ? 578 VAL A C 1 ATOM 4693 O O . VAL A 1 578 ? 58.086 81.666 -37.023 1.00 14.20 ? 578 VAL A O 1 ATOM 4694 C CB . VAL A 1 578 ? 58.779 83.245 -34.326 1.00 14.01 ? 578 VAL A CB 1 ATOM 4695 C CG1 . VAL A 1 578 ? 59.531 82.067 -33.585 1.00 15.97 ? 578 VAL A CG1 1 ATOM 4696 C CG2 . VAL A 1 578 ? 59.047 84.487 -33.619 1.00 15.82 ? 578 VAL A CG2 1 ATOM 4697 N N . SER A 1 579 ? 60.253 81.282 -36.599 1.00 15.34 ? 579 SER A N 1 ATOM 4698 C CA . SER A 1 579 ? 60.173 79.960 -37.179 1.00 15.86 ? 579 SER A CA 1 ATOM 4699 C C . SER A 1 579 ? 60.756 78.937 -36.206 1.00 11.94 ? 579 SER A C 1 ATOM 4700 O O . SER A 1 579 ? 61.523 79.266 -35.306 1.00 13.08 ? 579 SER A O 1 ATOM 4701 C CB . SER A 1 579 ? 60.798 79.901 -38.562 1.00 21.78 ? 579 SER A CB 1 ATOM 4702 O OG . SER A 1 579 ? 62.076 80.393 -38.490 1.00 23.72 ? 579 SER A OG 1 ATOM 4703 N N . VAL A 1 580 ? 60.377 77.703 -36.465 1.00 11.01 ? 580 VAL A N 1 ATOM 4704 C CA . VAL A 1 580 ? 60.723 76.621 -35.558 1.00 10.58 ? 580 VAL A CA 1 ATOM 4705 C C . VAL A 1 580 ? 61.601 75.588 -36.273 1.00 12.46 ? 580 VAL A C 1 ATOM 4706 O O . VAL A 1 580 ? 61.340 75.240 -37.446 1.00 12.98 ? 580 VAL A O 1 ATOM 4707 C CB . VAL A 1 580 ? 59.424 75.920 -35.070 1.00 10.54 ? 580 VAL A CB 1 ATOM 4708 C CG1 . VAL A 1 580 ? 59.752 74.795 -34.067 1.00 12.59 ? 580 VAL A CG1 1 ATOM 4709 C CG2 . VAL A 1 580 ? 58.491 76.937 -34.407 1.00 12.56 ? 580 VAL A CG2 1 ATOM 4710 N N . THR A 1 581 ? 62.577 75.077 -35.537 1.00 10.43 ? 581 THR A N 1 ATOM 4711 C CA . THR A 1 581 ? 63.440 73.987 -36.010 1.00 12.52 ? 581 THR A CA 1 ATOM 4712 C C . THR A 1 581 ? 63.596 72.974 -34.878 1.00 11.93 ? 581 THR A C 1 ATOM 4713 O O . THR A 1 581 ? 63.397 73.300 -33.696 1.00 12.15 ? 581 THR A O 1 ATOM 4714 C CB . THR A 1 581 ? 64.874 74.475 -36.405 1.00 14.04 ? 581 THR A CB 1 ATOM 4715 O OG1 . THR A 1 581 ? 65.374 75.390 -35.424 1.00 16.50 ? 581 THR A OG1 1 ATOM 4716 C CG2 . THR A 1 581 ? 64.769 75.284 -37.740 1.00 12.49 ? 581 THR A CG2 1 ATOM 4717 N N . ASP A 1 582 ? 63.930 71.742 -35.244 1.00 13.64 ? 582 ASP A N 1 ATOM 4718 C CA . ASP A 1 582 ? 64.284 70.708 -34.254 1.00 14.02 ? 582 ASP A CA 1 ATOM 4719 C C . ASP A 1 582 ? 65.801 70.857 -34.015 1.00 16.37 ? 582 ASP A C 1 ATOM 4720 O O . ASP A 1 582 ? 66.435 71.740 -34.565 1.00 18.14 ? 582 ASP A O 1 ATOM 4721 C CB . ASP A 1 582 ? 63.817 69.306 -34.676 1.00 19.93 ? 582 ASP A CB 1 ATOM 4722 C CG . ASP A 1 582 ? 64.532 68.741 -35.912 1.00 18.86 ? 582 ASP A CG 1 ATOM 4723 O OD1 . ASP A 1 582 ? 63.999 67.722 -36.430 1.00 21.54 ? 582 ASP A OD1 1 ATOM 4724 O OD2 . ASP A 1 582 ? 65.571 69.284 -36.317 1.00 16.77 ? 582 ASP A OD2 1 ATOM 4725 N N . LEU A 1 583 ? 66.427 70.050 -33.146 1.00 23.43 ? 583 LEU A N 1 ATOM 4726 C CA . LEU A 1 583 ? 67.839 70.368 -32.942 1.00 24.78 ? 583 LEU A CA 1 ATOM 4727 C C . LEU A 1 583 ? 68.746 69.928 -34.082 1.00 27.52 ? 583 LEU A C 1 ATOM 4728 O O . LEU A 1 583 ? 69.922 70.336 -34.124 1.00 29.97 ? 583 LEU A O 1 ATOM 4729 C CB . LEU A 1 583 ? 68.374 69.857 -31.573 1.00 25.51 ? 583 LEU A CB 1 ATOM 4730 C CG . LEU A 1 583 ? 69.289 70.856 -30.833 1.00 21.97 ? 583 LEU A CG 1 ATOM 4731 C CD1 . LEU A 1 583 ? 68.566 72.186 -30.745 1.00 28.21 ? 583 LEU A CD1 1 ATOM 4732 C CD2 . LEU A 1 583 ? 69.653 70.418 -29.404 1.00 27.14 ? 583 LEU A CD2 1 ATOM 4733 N N . ALA A 1 584 ? 68.217 69.141 -35.031 1.00 22.46 ? 584 ALA A N 1 ATOM 4734 C CA . ALA A 1 584 ? 69.057 68.824 -36.212 1.00 19.28 ? 584 ALA A CA 1 ATOM 4735 C C . ALA A 1 584 ? 68.821 69.926 -37.223 1.00 16.05 ? 584 ALA A C 1 ATOM 4736 O O . ALA A 1 584 ? 69.219 69.813 -38.402 1.00 17.00 ? 584 ALA A O 1 ATOM 4737 C CB . ALA A 1 584 ? 68.690 67.516 -36.844 1.00 17.20 ? 584 ALA A CB 1 ATOM 4738 N N . ASN A 1 585 ? 68.155 71.007 -36.819 1.00 16.73 ? 585 ASN A N 1 ATOM 4739 C CA . ASN A 1 585 ? 67.914 72.149 -37.688 1.00 16.58 ? 585 ASN A CA 1 ATOM 4740 C C . ASN A 1 585 ? 66.929 71.896 -38.823 1.00 17.99 ? 585 ASN A C 1 ATOM 4741 O O . ASN A 1 585 ? 66.911 72.630 -39.813 1.00 20.36 ? 585 ASN A O 1 ATOM 4742 C CB . ASN A 1 585 ? 69.257 72.668 -38.266 1.00 23.23 ? 585 ASN A CB 1 ATOM 4743 C CG . ASN A 1 585 ? 69.542 74.101 -37.909 1.00 31.69 ? 585 ASN A CG 1 ATOM 4744 O OD1 . ASN A 1 585 ? 68.650 74.974 -37.909 1.00 28.56 ? 585 ASN A OD1 1 ATOM 4745 N ND2 . ASN A 1 585 ? 70.806 74.372 -37.597 1.00 40.27 ? 585 ASN A ND2 1 ATOM 4746 N N . ASN A 1 586 ? 66.095 70.882 -38.704 1.00 13.82 ? 586 ASN A N 1 ATOM 4747 C CA . ASN A 1 586 ? 65.068 70.554 -39.692 1.00 16.45 ? 586 ASN A CA 1 ATOM 4748 C C . ASN A 1 586 ? 63.897 71.508 -39.402 1.00 17.66 ? 586 ASN A C 1 ATOM 4749 O O . ASN A 1 586 ? 63.469 71.683 -38.234 1.00 15.03 ? 586 ASN A O 1 ATOM 4750 C CB . ASN A 1 586 ? 64.506 69.158 -39.493 1.00 15.92 ? 586 ASN A CB 1 ATOM 4751 C CG . ASN A 1 586 ? 65.550 68.070 -39.603 1.00 19.78 ? 586 ASN A CG 1 ATOM 4752 O OD1 . ASN A 1 586 ? 66.413 68.114 -40.486 1.00 20.46 ? 586 ASN A OD1 1 ATOM 4753 N ND2 . ASN A 1 586 ? 65.489 67.089 -38.682 1.00 20.11 ? 586 ASN A ND2 1 ATOM 4754 N N . PRO A 1 587 ? 63.392 72.214 -40.414 1.00 16.79 ? 587 PRO A N 1 ATOM 4755 C CA . PRO A 1 587 ? 62.258 73.127 -40.185 1.00 15.73 ? 587 PRO A CA 1 ATOM 4756 C C . PRO A 1 587 ? 61.040 72.341 -39.727 1.00 14.15 ? 587 PRO A C 1 ATOM 4757 O O . PRO A 1 587 ? 60.849 71.164 -40.070 1.00 16.89 ? 587 PRO A O 1 ATOM 4758 C CB . PRO A 1 587 ? 62.041 73.820 -41.536 1.00 18.83 ? 587 PRO A CB 1 ATOM 4759 C CG . PRO A 1 587 ? 63.017 73.236 -42.494 1.00 23.25 ? 587 PRO A CG 1 ATOM 4760 C CD . PRO A 1 587 ? 63.943 72.272 -41.788 1.00 18.98 ? 587 PRO A CD 1 ATOM 4761 N N . VAL A 1 588 ? 60.199 72.992 -38.902 1.00 13.05 ? 588 VAL A N 1 ATOM 4762 C CA . VAL A 1 588 ? 58.988 72.397 -38.389 1.00 12.88 ? 588 VAL A CA 1 ATOM 4763 C C . VAL A 1 588 ? 57.876 73.396 -38.774 1.00 12.19 ? 588 VAL A C 1 ATOM 4764 O O . VAL A 1 588 ? 58.020 74.608 -38.497 1.00 12.48 ? 588 VAL A O 1 ATOM 4765 C CB . VAL A 1 588 ? 59.061 72.256 -36.806 1.00 13.81 ? 588 VAL A CB 1 ATOM 4766 C CG1 . VAL A 1 588 ? 57.723 71.866 -36.236 1.00 14.94 ? 588 VAL A CG1 1 ATOM 4767 C CG2 . VAL A 1 588 ? 60.213 71.265 -36.421 1.00 14.19 ? 588 VAL A CG2 1 ATOM 4768 N N . GLU A 1 589 ? 56.818 72.914 -39.378 1.00 13.03 ? 589 GLU A N 1 ATOM 4769 C CA . GLU A 1 589 ? 55.723 73.793 -39.777 1.00 12.88 ? 589 GLU A CA 1 ATOM 4770 C C . GLU A 1 589 ? 55.072 74.455 -38.541 1.00 13.04 ? 589 GLU A C 1 ATOM 4771 O O . GLU A 1 589 ? 54.816 73.769 -37.527 1.00 15.15 ? 589 GLU A O 1 ATOM 4772 C CB . GLU A 1 589 ? 54.664 73.001 -40.534 1.00 18.22 ? 589 GLU A CB 1 ATOM 4773 C CG . GLU A 1 589 ? 53.574 73.909 -41.100 1.00 26.82 ? 589 GLU A CG 1 ATOM 4774 C CD . GLU A 1 589 ? 52.460 73.171 -41.825 1.00 33.66 ? 589 GLU A CD 1 ATOM 4775 O OE1 . GLU A 1 589 ? 52.661 71.979 -42.138 1.00 38.90 ? 589 GLU A OE1 1 ATOM 4776 O OE2 . GLU A 1 589 ? 51.375 73.779 -42.089 1.00 33.49 ? 589 GLU A OE2 1 ATOM 4777 N N . ALA A 1 590 ? 54.777 75.733 -38.589 1.00 12.35 ? 590 ALA A N 1 ATOM 4778 C CA . ALA A 1 590 ? 54.241 76.436 -37.449 1.00 11.83 ? 590 ALA A CA 1 ATOM 4779 C C . ALA A 1 590 ? 53.134 77.368 -37.902 1.00 12.64 ? 590 ALA A C 1 ATOM 4780 O O . ALA A 1 590 ? 53.042 77.707 -39.123 1.00 13.23 ? 590 ALA A O 1 ATOM 4781 C CB . ALA A 1 590 ? 55.318 77.242 -36.775 1.00 12.78 ? 590 ALA A CB 1 ATOM 4782 N N . GLN A 1 591 ? 52.311 77.790 -36.974 1.00 12.15 ? 591 GLN A N 1 ATOM 4783 C CA . GLN A 1 591 ? 51.214 78.726 -37.229 1.00 10.98 ? 591 GLN A CA 1 ATOM 4784 C C . GLN A 1 591 ? 51.300 79.806 -36.170 1.00 12.24 ? 591 GLN A C 1 ATOM 4785 O O . GLN A 1 591 ? 51.531 79.514 -34.977 1.00 13.18 ? 591 GLN A O 1 ATOM 4786 C CB . GLN A 1 591 ? 49.848 78.012 -37.154 1.00 12.07 ? 591 GLN A CB 1 ATOM 4787 C CG . GLN A 1 591 ? 48.669 78.997 -37.132 1.00 12.28 ? 591 GLN A CG 1 ATOM 4788 C CD . GLN A 1 591 ? 47.325 78.290 -36.963 1.00 10.93 ? 591 GLN A CD 1 ATOM 4789 O OE1 . GLN A 1 591 ? 47.094 77.202 -37.539 1.00 12.64 ? 591 GLN A OE1 1 ATOM 4790 N NE2 . GLN A 1 591 ? 46.445 78.874 -36.165 1.00 12.46 ? 591 GLN A NE2 1 ATOM 4791 N N . VAL A 1 592 ? 51.163 81.086 -36.574 1.00 11.43 ? 592 VAL A N 1 ATOM 4792 C CA . VAL A 1 592 ? 51.106 82.178 -35.612 1.00 11.01 ? 592 VAL A CA 1 ATOM 4793 C C . VAL A 1 592 ? 49.688 82.715 -35.614 1.00 11.46 ? 592 VAL A C 1 ATOM 4794 O O . VAL A 1 592 ? 49.052 82.808 -36.679 1.00 13.10 ? 592 VAL A O 1 ATOM 4795 C CB . VAL A 1 592 ? 52.158 83.285 -35.959 1.00 11.71 ? 592 VAL A CB 1 ATOM 4796 C CG1 . VAL A 1 592 ? 51.916 84.565 -35.180 1.00 14.07 ? 592 VAL A CG1 1 ATOM 4797 C CG2 . VAL A 1 592 ? 53.599 82.736 -35.619 1.00 12.89 ? 592 VAL A CG2 1 ATOM 4798 N N . SER A 1 593 ? 49.180 82.983 -34.429 1.00 12.23 ? 593 SER A N 1 ATOM 4799 C CA . SER A 1 593 ? 47.818 83.529 -34.209 1.00 13.32 ? 593 SER A CA 1 ATOM 4800 C C . SER A 1 593 ? 47.957 84.645 -33.211 1.00 13.38 ? 593 SER A C 1 ATOM 4801 O O . SER A 1 593 ? 48.957 84.756 -32.474 1.00 14.79 ? 593 SER A O 1 ATOM 4802 C CB . SER A 1 593 ? 46.825 82.481 -33.595 1.00 13.87 ? 593 SER A CB 1 ATOM 4803 O OG . SER A 1 593 ? 46.640 81.317 -34.400 1.00 14.73 ? 593 SER A OG 1 ATOM 4804 N N . PRO A 1 594 ? 46.995 85.543 -33.148 1.00 11.72 ? 594 PRO A N 1 ATOM 4805 C CA . PRO A 1 594 ? 47.096 86.626 -32.156 1.00 12.58 ? 594 PRO A CA 1 ATOM 4806 C C . PRO A 1 594 ? 46.853 86.140 -30.720 1.00 12.07 ? 594 PRO A C 1 ATOM 4807 O O . PRO A 1 594 ? 46.384 84.968 -30.516 1.00 13.04 ? 594 PRO A O 1 ATOM 4808 C CB . PRO A 1 594 ? 45.964 87.606 -32.556 1.00 13.67 ? 594 PRO A CB 1 ATOM 4809 C CG . PRO A 1 594 ? 45.566 87.138 -33.993 1.00 13.46 ? 594 PRO A CG 1 ATOM 4810 C CD . PRO A 1 594 ? 45.780 85.668 -33.985 1.00 13.00 ? 594 PRO A CD 1 ATOM 4811 N N . VAL A 1 595 ? 47.164 86.981 -29.725 1.00 12.32 ? 595 VAL A N 1 ATOM 4812 C CA . VAL A 1 595 ? 46.797 86.649 -28.356 1.00 12.67 ? 595 VAL A CA 1 ATOM 4813 C C . VAL A 1 595 ? 45.530 87.452 -28.098 1.00 12.70 ? 595 VAL A C 1 ATOM 4814 O O . VAL A 1 595 ? 45.543 88.701 -28.144 1.00 14.66 ? 595 VAL A O 1 ATOM 4815 C CB . VAL A 1 595 ? 47.875 87.035 -27.320 1.00 14.44 ? 595 VAL A CB 1 ATOM 4816 C CG1 . VAL A 1 595 ? 47.307 86.782 -25.894 1.00 13.71 ? 595 VAL A CG1 1 ATOM 4817 C CG2 . VAL A 1 595 ? 49.159 86.211 -27.588 1.00 14.82 ? 595 VAL A CG2 1 ATOM 4818 N N . TRP A 1 596 ? 44.411 86.755 -27.877 1.00 12.29 ? 596 TRP A N 1 ATOM 4819 C CA . TRP A 1 596 ? 43.106 87.370 -27.676 1.00 13.67 ? 596 TRP A CA 1 ATOM 4820 C C . TRP A 1 596 ? 42.694 87.286 -26.234 1.00 16.02 ? 596 TRP A C 1 ATOM 4821 O O . TRP A 1 596 ? 42.824 86.207 -25.624 1.00 17.67 ? 596 TRP A O 1 ATOM 4822 C CB . TRP A 1 596 ? 42.040 86.607 -28.539 1.00 13.21 ? 596 TRP A CB 1 ATOM 4823 C CG . TRP A 1 596 ? 42.192 86.791 -30.008 1.00 11.90 ? 596 TRP A CG 1 ATOM 4824 C CD1 . TRP A 1 596 ? 42.578 85.854 -30.948 1.00 11.49 ? 596 TRP A CD1 1 ATOM 4825 C CD2 . TRP A 1 596 ? 41.880 87.974 -30.755 1.00 12.16 ? 596 TRP A CD2 1 ATOM 4826 N NE1 . TRP A 1 596 ? 42.523 86.398 -32.222 1.00 13.63 ? 596 TRP A NE1 1 ATOM 4827 C CE2 . TRP A 1 596 ? 42.095 87.698 -32.115 1.00 13.41 ? 596 TRP A CE2 1 ATOM 4828 C CE3 . TRP A 1 596 ? 41.431 89.252 -30.394 1.00 12.14 ? 596 TRP A CE3 1 ATOM 4829 C CZ2 . TRP A 1 596 ? 41.880 88.651 -33.105 1.00 14.50 ? 596 TRP A CZ2 1 ATOM 4830 C CZ3 . TRP A 1 596 ? 41.223 90.203 -31.392 1.00 14.88 ? 596 TRP A CZ3 1 ATOM 4831 C CH2 . TRP A 1 596 ? 41.446 89.890 -32.710 1.00 15.96 ? 596 TRP A CH2 1 ATOM 4832 N N . SER A 1 597 ? 42.254 88.387 -25.657 1.00 15.41 ? 597 SER A N 1 ATOM 4833 C CA . SER A 1 597 ? 41.737 88.343 -24.302 1.00 17.55 ? 597 SER A CA 1 ATOM 4834 C C . SER A 1 597 ? 40.333 88.943 -24.322 1.00 17.34 ? 597 SER A C 1 ATOM 4835 O O . SER A 1 597 ? 40.084 89.951 -25.020 1.00 21.15 ? 597 SER A O 1 ATOM 4836 C CB . SER A 1 597 ? 42.607 89.121 -23.349 1.00 22.17 ? 597 SER A CB 1 ATOM 4837 O OG . SER A 1 597 ? 42.768 90.358 -23.898 1.00 28.35 ? 597 SER A OG 1 ATOM 4838 N N . TRP A 1 598 ? 39.440 88.370 -23.551 1.00 14.51 ? 598 TRP A N 1 ATOM 4839 C CA . TRP A 1 598 ? 38.051 88.827 -23.499 1.00 14.55 ? 598 TRP A CA 1 ATOM 4840 C C . TRP A 1 598 ? 37.803 89.780 -22.327 1.00 15.64 ? 598 TRP A C 1 ATOM 4841 O O . TRP A 1 598 ? 38.230 89.558 -21.199 1.00 19.64 ? 598 TRP A O 1 ATOM 4842 C CB . TRP A 1 598 ? 37.121 87.613 -23.403 1.00 15.21 ? 598 TRP A CB 1 ATOM 4843 C CG . TRP A 1 598 ? 37.084 86.833 -24.714 1.00 12.80 ? 598 TRP A CG 1 ATOM 4844 C CD1 . TRP A 1 598 ? 38.013 85.942 -25.169 1.00 13.19 ? 598 TRP A CD1 1 ATOM 4845 C CD2 . TRP A 1 598 ? 36.079 86.915 -25.707 1.00 12.72 ? 598 TRP A CD2 1 ATOM 4846 N NE1 . TRP A 1 598 ? 37.618 85.448 -26.410 1.00 12.66 ? 598 TRP A NE1 1 ATOM 4847 C CE2 . TRP A 1 598 ? 36.440 86.037 -26.754 1.00 12.18 ? 598 TRP A CE2 1 ATOM 4848 C CE3 . TRP A 1 598 ? 34.872 87.650 -25.828 1.00 13.51 ? 598 TRP A CE3 1 ATOM 4849 C CZ2 . TRP A 1 598 ? 35.665 85.868 -27.887 1.00 13.55 ? 598 TRP A CZ2 1 ATOM 4850 C CZ3 . TRP A 1 598 ? 34.093 87.458 -26.980 1.00 12.37 ? 598 TRP A CZ3 1 ATOM 4851 C CH2 . TRP A 1 598 ? 34.504 86.579 -27.977 1.00 13.37 ? 598 TRP A CH2 1 ATOM 4852 N N A HIS A 1 599 ? 37.042 90.806 -22.621 0.50 18.15 ? 599 HIS A N 1 ATOM 4853 N N B HIS A 1 599 ? 37.042 90.806 -22.621 0.50 20.72 ? 599 HIS A N 1 ATOM 4854 C CA A HIS A 1 599 ? 36.786 91.831 -21.645 0.50 20.63 ? 599 HIS A CA 1 ATOM 4855 C CA B HIS A 1 599 ? 36.786 91.831 -21.645 0.50 25.07 ? 599 HIS A CA 1 ATOM 4856 C C A HIS A 1 599 ? 35.327 92.096 -21.483 0.50 19.76 ? 599 HIS A C 1 ATOM 4857 C C B HIS A 1 599 ? 35.383 92.332 -21.717 0.50 25.42 ? 599 HIS A C 1 ATOM 4858 O O A HIS A 1 599 ? 34.589 92.164 -22.465 0.50 16.24 ? 599 HIS A O 1 ATOM 4859 O O B HIS A 1 599 ? 34.751 92.281 -22.771 0.50 26.45 ? 599 HIS A O 1 ATOM 4860 C CB A HIS A 1 599 ? 37.498 93.100 -22.093 0.50 24.76 ? 599 HIS A CB 1 ATOM 4861 C CB B HIS A 1 599 ? 37.760 92.975 -21.893 0.50 31.78 ? 599 HIS A CB 1 ATOM 4862 C CG A HIS A 1 599 ? 38.985 92.941 -22.053 0.50 30.79 ? 599 HIS A CG 1 ATOM 4863 C CG B HIS A 1 599 ? 37.093 94.307 -21.754 0.50 35.48 ? 599 HIS A CG 1 ATOM 4864 N ND1 A HIS A 1 599 ? 39.663 92.674 -20.875 0.50 33.02 ? 599 HIS A ND1 1 ATOM 4865 N ND1 B HIS A 1 599 ? 37.147 95.036 -20.578 0.50 38.85 ? 599 HIS A ND1 1 ATOM 4866 C CD2 A HIS A 1 599 ? 39.895 92.811 -23.046 0.50 33.18 ? 599 HIS A CD2 1 ATOM 4867 C CD2 B HIS A 1 599 ? 36.537 95.126 -22.677 0.50 38.73 ? 599 HIS A CD2 1 ATOM 4868 C CE1 A HIS A 1 599 ? 40.921 92.380 -21.152 0.50 34.40 ? 599 HIS A CE1 1 ATOM 4869 C CE1 B HIS A 1 599 ? 36.660 96.245 -20.791 0.50 38.29 ? 599 HIS A CE1 1 ATOM 4870 N NE2 A HIS A 1 599 ? 41.087 92.455 -22.461 0.50 32.71 ? 599 HIS A NE2 1 ATOM 4871 N NE2 B HIS A 1 599 ? 36.285 96.326 -22.055 0.50 39.35 ? 599 HIS A NE2 1 ATOM 4872 N N . HIS A 1 600 ? 34.920 92.229 -20.237 1.00 24.44 ? 600 HIS A N 1 ATOM 4873 C CA . HIS A 1 600 ? 33.538 92.547 -19.920 1.00 22.75 ? 600 HIS A CA 1 ATOM 4874 C C . HIS A 1 600 ? 33.650 94.039 -19.866 1.00 23.09 ? 600 HIS A C 1 ATOM 4875 O O . HIS A 1 600 ? 34.207 94.612 -18.915 1.00 28.24 ? 600 HIS A O 1 ATOM 4876 C CB . HIS A 1 600 ? 33.195 91.875 -18.594 1.00 27.27 ? 600 HIS A CB 1 ATOM 4877 C CG . HIS A 1 600 ? 33.506 90.413 -18.638 1.00 35.65 ? 600 HIS A CG 1 ATOM 4878 N ND1 . HIS A 1 600 ? 34.754 89.952 -19.008 1.00 38.61 ? 600 HIS A ND1 1 ATOM 4879 C CD2 . HIS A 1 600 ? 32.704 89.318 -18.585 1.00 39.25 ? 600 HIS A CD2 1 ATOM 4880 C CE1 . HIS A 1 600 ? 34.709 88.643 -19.193 1.00 41.59 ? 600 HIS A CE1 1 ATOM 4881 N NE2 . HIS A 1 600 ? 33.475 88.232 -18.944 1.00 42.48 ? 600 HIS A NE2 1 ATOM 4882 N N . ASP A 1 601 ? 33.178 94.663 -20.933 1.00 22.82 ? 601 ASP A N 1 ATOM 4883 C CA . ASP A 1 601 ? 33.288 96.085 -21.112 1.00 23.49 ? 601 ASP A CA 1 ATOM 4884 C C . ASP A 1 601 ? 32.148 96.749 -20.322 1.00 25.95 ? 601 ASP A C 1 ATOM 4885 O O . ASP A 1 601 ? 30.993 96.676 -20.737 1.00 23.86 ? 601 ASP A O 1 ATOM 4886 C CB . ASP A 1 601 ? 33.192 96.359 -22.611 1.00 24.42 ? 601 ASP A CB 1 ATOM 4887 C CG . ASP A 1 601 ? 33.553 97.774 -22.993 1.00 30.28 ? 601 ASP A CG 1 ATOM 4888 O OD1 . ASP A 1 601 ? 33.311 98.713 -22.191 1.00 28.30 ? 601 ASP A OD1 1 ATOM 4889 O OD2 . ASP A 1 601 ? 34.045 97.953 -24.130 1.00 27.92 ? 601 ASP A OD2 1 ATOM 4890 N N . THR A 1 602 ? 32.472 97.357 -19.176 1.00 25.98 ? 602 THR A N 1 ATOM 4891 C CA . THR A 1 602 ? 31.427 97.986 -18.372 1.00 29.26 ? 602 THR A CA 1 ATOM 4892 C C . THR A 1 602 ? 30.886 99.273 -18.960 1.00 28.73 ? 602 THR A C 1 ATOM 4893 O O . THR A 1 602 ? 29.882 99.776 -18.455 1.00 30.16 ? 602 THR A O 1 ATOM 4894 C CB . THR A 1 602 ? 31.868 98.247 -16.921 1.00 30.57 ? 602 THR A CB 1 ATOM 4895 O OG1 . THR A 1 602 ? 33.008 99.116 -16.912 1.00 35.17 ? 602 THR A OG1 1 ATOM 4896 C CG2 . THR A 1 602 ? 32.194 96.934 -16.218 1.00 33.80 ? 602 THR A CG2 1 ATOM 4897 N N . LEU A 1 603 ? 31.513 99.796 -20.015 1.00 26.13 ? 603 LEU A N 1 ATOM 4898 C CA . LEU A 1 603 ? 31.026 100.993 -20.703 1.00 27.78 ? 603 LEU A CA 1 ATOM 4899 C C . LEU A 1 603 ? 30.003 100.635 -21.797 1.00 26.39 ? 603 LEU A C 1 ATOM 4900 O O . LEU A 1 603 ? 28.879 101.124 -21.773 1.00 23.72 ? 603 LEU A O 1 ATOM 4901 C CB . LEU A 1 603 ? 32.179 101.796 -21.328 1.00 32.71 ? 603 LEU A CB 1 ATOM 4902 C CG . LEU A 1 603 ? 33.002 102.743 -20.439 1.00 37.82 ? 603 LEU A CG 1 ATOM 4903 C CD1 . LEU A 1 603 ? 32.045 103.730 -19.720 1.00 39.31 ? 603 LEU A CD1 1 ATOM 4904 C CD2 . LEU A 1 603 ? 33.798 101.954 -19.421 1.00 40.40 ? 603 LEU A CD2 1 ATOM 4905 N N . THR A 1 604 ? 30.375 99.766 -22.753 1.00 21.91 ? 604 THR A N 1 ATOM 4906 C CA . THR A 1 604 ? 29.476 99.342 -23.814 1.00 21.10 ? 604 THR A CA 1 ATOM 4907 C C . THR A 1 604 ? 28.510 98.239 -23.366 1.00 17.51 ? 604 THR A C 1 ATOM 4908 O O . THR A 1 604 ? 27.587 97.908 -24.113 1.00 19.05 ? 604 THR A O 1 ATOM 4909 C CB . THR A 1 604 ? 30.247 98.806 -25.052 1.00 23.03 ? 604 THR A CB 1 ATOM 4910 O OG1 . THR A 1 604 ? 31.053 97.666 -24.662 1.00 23.51 ? 604 THR A OG1 1 ATOM 4911 C CG2 . THR A 1 604 ? 31.165 99.917 -25.631 1.00 23.32 ? 604 THR A CG2 1 ATOM 4912 N N . LYS A 1 605 ? 28.797 97.625 -22.219 1.00 17.60 ? 605 LYS A N 1 ATOM 4913 C CA . LYS A 1 605 ? 27.953 96.528 -21.688 1.00 18.64 ? 605 LYS A CA 1 ATOM 4914 C C . LYS A 1 605 ? 27.965 95.337 -22.666 1.00 21.35 ? 605 LYS A C 1 ATOM 4915 O O . LYS A 1 605 ? 26.932 94.759 -22.993 1.00 21.85 ? 605 LYS A O 1 ATOM 4916 C CB . LYS A 1 605 ? 26.479 96.970 -21.444 1.00 20.62 ? 605 LYS A CB 1 ATOM 4917 C CG . LYS A 1 605 ? 26.370 98.155 -20.517 1.00 20.78 ? 605 LYS A CG 1 ATOM 4918 C CD . LYS A 1 605 ? 26.797 97.758 -19.108 1.00 20.32 ? 605 LYS A CD 1 ATOM 4919 C CE . LYS A 1 605 ? 26.719 98.979 -18.140 1.00 21.02 ? 605 LYS A CE 1 ATOM 4920 N NZ . LYS A 1 605 ? 26.962 98.528 -16.748 1.00 26.70 ? 605 LYS A NZ 1 ATOM 4921 N N . THR A 1 606 ? 29.146 95.012 -23.179 1.00 18.47 ? 606 THR A N 1 ATOM 4922 C CA . THR A 1 606 ? 29.294 93.856 -24.081 1.00 18.59 ? 606 THR A CA 1 ATOM 4923 C C . THR A 1 606 ? 30.540 93.120 -23.647 1.00 15.93 ? 606 THR A C 1 ATOM 4924 O O . THR A 1 606 ? 31.386 93.650 -22.960 1.00 17.23 ? 606 THR A O 1 ATOM 4925 C CB . THR A 1 606 ? 29.486 94.256 -25.562 1.00 20.45 ? 606 THR A CB 1 ATOM 4926 O OG1 . THR A 1 606 ? 30.645 95.091 -25.685 1.00 23.65 ? 606 THR A OG1 1 ATOM 4927 C CG2 . THR A 1 606 ? 28.236 94.946 -26.116 1.00 20.77 ? 606 THR A CG2 1 ATOM 4928 N N . ILE A 1 607 ? 30.634 91.847 -24.030 1.00 15.91 ? 607 ILE A N 1 ATOM 4929 C CA . ILE A 1 607 ? 31.807 91.019 -23.685 1.00 13.99 ? 607 ILE A CA 1 ATOM 4930 C C . ILE A 1 607 ? 32.483 90.799 -25.037 1.00 13.60 ? 607 ILE A C 1 ATOM 4931 O O . ILE A 1 607 ? 31.918 90.180 -25.967 1.00 13.60 ? 607 ILE A O 1 ATOM 4932 C CB . ILE A 1 607 ? 31.316 89.696 -23.094 1.00 14.56 ? 607 ILE A CB 1 ATOM 4933 C CG1 . ILE A 1 607 ? 30.501 89.983 -21.824 1.00 17.06 ? 607 ILE A CG1 1 ATOM 4934 C CG2 . ILE A 1 607 ? 32.544 88.813 -22.756 1.00 15.77 ? 607 ILE A CG2 1 ATOM 4935 C CD1 . ILE A 1 607 ? 29.632 88.829 -21.361 1.00 21.05 ? 607 ILE A CD1 1 ATOM 4936 N N . HIS A 1 608 ? 33.710 91.305 -25.200 1.00 14.53 ? 608 HIS A N 1 ATOM 4937 C CA . HIS A 1 608 ? 34.321 91.247 -26.542 1.00 16.06 ? 608 HIS A CA 1 ATOM 4938 C C . HIS A 1 608 ? 35.821 91.076 -26.427 1.00 14.89 ? 608 HIS A C 1 ATOM 4939 O O . HIS A 1 608 ? 36.391 91.398 -25.379 1.00 16.75 ? 608 HIS A O 1 ATOM 4940 C CB . HIS A 1 608 ? 33.968 92.505 -27.358 1.00 19.36 ? 608 HIS A CB 1 ATOM 4941 C CG . HIS A 1 608 ? 34.527 93.777 -26.802 1.00 22.29 ? 608 HIS A CG 1 ATOM 4942 N ND1 . HIS A 1 608 ? 33.921 94.516 -25.800 1.00 25.59 ? 608 HIS A ND1 1 ATOM 4943 C CD2 . HIS A 1 608 ? 35.671 94.440 -27.110 1.00 25.09 ? 608 HIS A CD2 1 ATOM 4944 C CE1 . HIS A 1 608 ? 34.662 95.580 -25.523 1.00 25.33 ? 608 HIS A CE1 1 ATOM 4945 N NE2 . HIS A 1 608 ? 35.727 95.557 -26.301 1.00 30.13 ? 608 HIS A NE2 1 ATOM 4946 N N . PRO A 1 609 ? 36.465 90.597 -27.474 1.00 14.37 ? 609 PRO A N 1 ATOM 4947 C CA . PRO A 1 609 ? 37.898 90.371 -27.410 1.00 14.68 ? 609 PRO A CA 1 ATOM 4948 C C . PRO A 1 609 ? 38.784 91.499 -27.861 1.00 15.32 ? 609 PRO A C 1 ATOM 4949 O O . PRO A 1 609 ? 38.444 92.241 -28.805 1.00 20.00 ? 609 PRO A O 1 ATOM 4950 C CB . PRO A 1 609 ? 38.083 89.160 -28.314 1.00 16.55 ? 609 PRO A CB 1 ATOM 4951 C CG . PRO A 1 609 ? 37.061 89.401 -29.417 1.00 16.18 ? 609 PRO A CG 1 ATOM 4952 C CD . PRO A 1 609 ? 35.902 90.086 -28.750 1.00 12.66 ? 609 PRO A CD 1 ATOM 4953 N N . GLN A 1 610 ? 39.936 91.550 -27.210 1.00 14.62 ? 610 GLN A N 1 ATOM 4954 C CA . GLN A 1 610 ? 40.952 92.528 -27.532 1.00 17.24 ? 610 GLN A CA 1 ATOM 4955 C C . GLN A 1 610 ? 42.192 91.748 -27.947 1.00 13.91 ? 610 GLN A C 1 ATOM 4956 O O . GLN A 1 610 ? 42.503 90.753 -27.273 1.00 14.76 ? 610 GLN A O 1 ATOM 4957 C CB . GLN A 1 610 ? 41.276 93.382 -26.303 1.00 20.68 ? 610 GLN A CB 1 ATOM 4958 C CG . GLN A 1 610 ? 40.072 94.143 -25.814 1.00 33.15 ? 610 GLN A CG 1 ATOM 4959 C CD . GLN A 1 610 ? 39.805 95.396 -26.625 1.00 39.51 ? 610 GLN A CD 1 ATOM 4960 O OE1 . GLN A 1 610 ? 39.238 95.358 -27.739 1.00 42.59 ? 610 GLN A OE1 1 ATOM 4961 N NE2 . GLN A 1 610 ? 40.221 96.533 -26.067 1.00 43.58 ? 610 GLN A NE2 1 ATOM 4962 N N . GLY A 1 611 ? 42.869 92.192 -28.992 1.00 14.68 ? 611 GLY A N 1 ATOM 4963 C CA . GLY A 1 611 ? 44.090 91.501 -29.409 1.00 14.79 ? 611 GLY A CA 1 ATOM 4964 C C . GLY A 1 611 ? 45.332 92.266 -28.975 1.00 16.36 ? 611 GLY A C 1 ATOM 4965 O O . GLY A 1 611 ? 45.354 93.496 -28.888 1.00 18.21 ? 611 GLY A O 1 ATOM 4966 N N . SER A 1 612 ? 46.382 91.531 -28.693 1.00 16.80 ? 612 SER A N 1 ATOM 4967 C CA . SER A 1 612 ? 47.653 92.161 -28.318 1.00 17.52 ? 612 SER A CA 1 ATOM 4968 C C . SER A 1 612 ? 48.345 92.667 -29.546 1.00 14.22 ? 612 SER A C 1 ATOM 4969 O O . SER A 1 612 ? 48.273 92.093 -30.613 1.00 18.22 ? 612 SER A O 1 ATOM 4970 C CB . SER A 1 612 ? 48.529 91.092 -27.672 1.00 17.31 ? 612 SER A CB 1 ATOM 4971 O OG . SER A 1 612 ? 49.806 91.652 -27.352 1.00 19.28 ? 612 SER A OG 1 ATOM 4972 N N . THR A 1 613 ? 49.050 93.807 -29.396 1.00 23.18 ? 613 THR A N 1 ATOM 4973 C CA . THR A 1 613 ? 49.786 94.316 -30.540 1.00 23.09 ? 613 THR A CA 1 ATOM 4974 C C . THR A 1 613 ? 51.302 94.091 -30.367 1.00 26.60 ? 613 THR A C 1 ATOM 4975 O O . THR A 1 613 ? 52.107 94.571 -31.192 1.00 28.66 ? 613 THR A O 1 ATOM 4976 C CB . THR A 1 613 ? 49.556 95.818 -30.759 1.00 26.11 ? 613 THR A CB 1 ATOM 4977 O OG1 . THR A 1 613 ? 50.044 96.513 -29.607 1.00 22.91 ? 613 THR A OG1 1 ATOM 4978 C CG2 . THR A 1 613 ? 48.060 96.112 -30.880 1.00 25.65 ? 613 THR A CG2 1 ATOM 4979 N N . THR A 1 614 ? 51.673 93.321 -29.343 1.00 25.67 ? 614 THR A N 1 ATOM 4980 C CA . THR A 1 614 ? 53.098 93.028 -29.106 1.00 25.59 ? 614 THR A CA 1 ATOM 4981 C C . THR A 1 614 ? 53.428 91.601 -28.618 1.00 26.33 ? 614 THR A C 1 ATOM 4982 O O . THR A 1 614 ? 54.584 91.317 -28.324 1.00 27.15 ? 614 THR A O 1 ATOM 4983 C CB . THR A 1 614 ? 53.622 93.899 -28.068 1.00 25.72 ? 614 THR A CB 1 ATOM 4984 O OG1 . THR A 1 614 ? 52.830 93.676 -26.918 1.00 26.30 ? 614 THR A OG1 1 ATOM 4985 C CG2 . THR A 1 614 ? 53.631 95.376 -28.517 1.00 28.20 ? 614 THR A CG2 1 ATOM 4986 N N . LYS A 1 615 ? 52.430 90.734 -28.456 1.00 19.45 ? 615 LYS A N 1 ATOM 4987 C CA . LYS A 1 615 ? 52.662 89.345 -28.039 1.00 18.93 ? 615 LYS A CA 1 ATOM 4988 C C . LYS A 1 615 ? 51.847 88.584 -29.071 1.00 17.91 ? 615 LYS A C 1 ATOM 4989 O O . LYS A 1 615 ? 50.739 89.023 -29.408 1.00 17.89 ? 615 LYS A O 1 ATOM 4990 C CB . LYS A 1 615 ? 51.982 88.927 -26.701 1.00 24.82 ? 615 LYS A CB 1 ATOM 4991 C CG . LYS A 1 615 ? 52.444 89.462 -25.377 1.00 30.72 ? 615 LYS A CG 1 ATOM 4992 C CD . LYS A 1 615 ? 52.222 88.425 -24.222 1.00 26.55 ? 615 LYS A CD 1 ATOM 4993 C CE . LYS A 1 615 ? 50.762 88.095 -23.836 1.00 25.05 ? 615 LYS A CE 1 ATOM 4994 N NZ . LYS A 1 615 ? 50.712 88.113 -22.288 1.00 25.30 ? 615 LYS A NZ 1 ATOM 4995 N N . TYR A 1 616 ? 52.347 87.416 -29.502 1.00 14.23 ? 616 TYR A N 1 ATOM 4996 C CA . TYR A 1 616 ? 51.678 86.547 -30.450 1.00 13.86 ? 616 TYR A CA 1 ATOM 4997 C C . TYR A 1 616 ? 51.822 85.120 -29.998 1.00 11.51 ? 616 TYR A C 1 ATOM 4998 O O . TYR A 1 616 ? 52.731 84.820 -29.180 1.00 14.00 ? 616 TYR A O 1 ATOM 4999 C CB . TYR A 1 616 ? 52.331 86.683 -31.839 1.00 13.08 ? 616 TYR A CB 1 ATOM 5000 C CG . TYR A 1 616 ? 52.316 88.126 -32.247 1.00 18.34 ? 616 TYR A CG 1 ATOM 5001 C CD1 . TYR A 1 616 ? 53.364 88.981 -31.908 1.00 17.22 ? 616 TYR A CD1 1 ATOM 5002 C CD2 . TYR A 1 616 ? 51.153 88.654 -32.859 1.00 19.20 ? 616 TYR A CD2 1 ATOM 5003 C CE1 . TYR A 1 616 ? 53.249 90.382 -32.175 1.00 23.65 ? 616 TYR A CE1 1 ATOM 5004 C CE2 . TYR A 1 616 ? 51.031 89.991 -33.109 1.00 23.56 ? 616 TYR A CE2 1 ATOM 5005 C CZ . TYR A 1 616 ? 52.069 90.835 -32.775 1.00 23.02 ? 616 TYR A CZ 1 ATOM 5006 O OH . TYR A 1 616 ? 51.907 92.164 -33.150 1.00 28.28 ? 616 TYR A OH 1 ATOM 5007 N N . ARG A 1 617 ? 50.975 84.231 -30.505 1.00 12.64 ? 617 ARG A N 1 ATOM 5008 C CA . ARG A 1 617 ? 51.083 82.799 -30.179 1.00 12.82 ? 617 ARG A CA 1 ATOM 5009 C C . ARG A 1 617 ? 51.704 82.053 -31.347 1.00 13.46 ? 617 ARG A C 1 ATOM 5010 O O . ARG A 1 617 ? 51.222 82.190 -32.500 1.00 14.95 ? 617 ARG A O 1 ATOM 5011 C CB . ARG A 1 617 ? 49.714 82.167 -29.983 1.00 16.53 ? 617 ARG A CB 1 ATOM 5012 C CG . ARG A 1 617 ? 49.015 82.487 -28.698 1.00 20.13 ? 617 ARG A CG 1 ATOM 5013 C CD . ARG A 1 617 ? 47.594 81.846 -28.657 1.00 21.46 ? 617 ARG A CD 1 ATOM 5014 N NE . ARG A 1 617 ? 47.593 80.378 -28.640 1.00 18.08 ? 617 ARG A NE 1 ATOM 5015 C CZ . ARG A 1 617 ? 46.864 79.612 -29.460 1.00 19.95 ? 617 ARG A CZ 1 ATOM 5016 N NH1 . ARG A 1 617 ? 46.043 80.131 -30.393 1.00 18.07 ? 617 ARG A NH1 1 ATOM 5017 N NH2 . ARG A 1 617 ? 46.982 78.291 -29.399 1.00 18.78 ? 617 ARG A NH2 1 ATOM 5018 N N . ILE A 1 618 ? 52.734 81.235 -31.102 1.00 11.37 ? 618 ILE A N 1 ATOM 5019 C CA . ILE A 1 618 ? 53.255 80.384 -32.146 1.00 12.65 ? 618 ILE A CA 1 ATOM 5020 C C . ILE A 1 618 ? 52.883 78.952 -31.763 1.00 10.30 ? 618 ILE A C 1 ATOM 5021 O O . ILE A 1 618 ? 53.022 78.552 -30.584 1.00 12.45 ? 618 ILE A O 1 ATOM 5022 C CB . ILE A 1 618 ? 54.704 80.565 -32.372 1.00 12.19 ? 618 ILE A CB 1 ATOM 5023 C CG1 . ILE A 1 618 ? 55.081 79.739 -33.617 1.00 16.47 ? 618 ILE A CG1 1 ATOM 5024 C CG2 . ILE A 1 618 ? 55.558 80.236 -31.136 1.00 14.73 ? 618 ILE A CG2 1 ATOM 5025 C CD1 . ILE A 1 618 ? 56.355 80.144 -34.273 1.00 15.46 ? 618 ILE A CD1 1 ATOM 5026 N N . ILE A 1 619 ? 52.433 78.179 -32.720 1.00 10.78 ? 619 ILE A N 1 ATOM 5027 C CA . ILE A 1 619 ? 51.911 76.831 -32.493 1.00 10.56 ? 619 ILE A CA 1 ATOM 5028 C C . ILE A 1 619 ? 52.618 75.859 -33.427 1.00 11.60 ? 619 ILE A C 1 ATOM 5029 O O . ILE A 1 619 ? 52.802 76.173 -34.641 1.00 11.58 ? 619 ILE A O 1 ATOM 5030 C CB . ILE A 1 619 ? 50.384 76.839 -32.883 1.00 13.84 ? 619 ILE A CB 1 ATOM 5031 C CG1 . ILE A 1 619 ? 49.677 77.882 -32.042 1.00 14.55 ? 619 ILE A CG1 1 ATOM 5032 C CG2 . ILE A 1 619 ? 49.758 75.462 -32.802 1.00 16.39 ? 619 ILE A CG2 1 ATOM 5033 C CD1 . ILE A 1 619 ? 48.465 78.563 -32.802 1.00 17.90 ? 619 ILE A CD1 1 ATOM 5034 N N . PHE A 1 620 ? 53.027 74.688 -32.966 1.00 10.19 ? 620 PHE A N 1 ATOM 5035 C CA . PHE A 1 620 ? 53.656 73.728 -33.867 1.00 9.98 ? 620 PHE A CA 1 ATOM 5036 C C . PHE A 1 620 ? 53.467 72.344 -33.263 1.00 10.32 ? 620 PHE A C 1 ATOM 5037 O O . PHE A 1 620 ? 53.154 72.236 -32.052 1.00 10.72 ? 620 PHE A O 1 ATOM 5038 C CB . PHE A 1 620 ? 55.150 74.021 -34.078 1.00 10.22 ? 620 PHE A CB 1 ATOM 5039 C CG . PHE A 1 620 ? 55.993 73.936 -32.825 1.00 9.23 ? 620 PHE A CG 1 ATOM 5040 C CD1 . PHE A 1 620 ? 56.647 72.737 -32.497 1.00 11.86 ? 620 PHE A CD1 1 ATOM 5041 C CD2 . PHE A 1 620 ? 56.190 75.064 -32.028 1.00 10.72 ? 620 PHE A CD2 1 ATOM 5042 C CE1 . PHE A 1 620 ? 57.505 72.661 -31.369 1.00 11.54 ? 620 PHE A CE1 1 ATOM 5043 C CE2 . PHE A 1 620 ? 57.057 74.992 -30.893 1.00 11.58 ? 620 PHE A CE2 1 ATOM 5044 C CZ . PHE A 1 620 ? 57.687 73.780 -30.598 1.00 11.94 ? 620 PHE A CZ 1 ATOM 5045 N N . LYS A 1 621 ? 53.664 71.317 -34.079 1.00 9.90 ? 621 LYS A N 1 ATOM 5046 C CA . LYS A 1 621 ? 53.524 69.965 -33.608 1.00 10.49 ? 621 LYS A CA 1 ATOM 5047 C C . LYS A 1 621 ? 54.819 69.455 -33.024 1.00 12.05 ? 621 LYS A C 1 ATOM 5048 O O . LYS A 1 621 ? 55.862 69.417 -33.694 1.00 14.17 ? 621 LYS A O 1 ATOM 5049 C CB . LYS A 1 621 ? 53.055 69.110 -34.801 1.00 11.73 ? 621 LYS A CB 1 ATOM 5050 C CG . LYS A 1 621 ? 52.775 67.644 -34.399 1.00 13.93 ? 621 LYS A CG 1 ATOM 5051 C CD . LYS A 1 621 ? 51.982 66.942 -35.545 1.00 19.18 ? 621 LYS A CD 1 ATOM 5052 C CE . LYS A 1 621 ? 52.653 66.988 -36.865 1.00 23.35 ? 621 LYS A CE 1 ATOM 5053 N NZ . LYS A 1 621 ? 51.792 66.250 -37.894 1.00 26.68 ? 621 LYS A NZ 1 ATOM 5054 N N . ALA A 1 622 ? 54.782 69.120 -31.729 1.00 11.20 ? 622 ALA A N 1 ATOM 5055 C CA . ALA A 1 622 ? 55.975 68.502 -31.104 1.00 10.57 ? 622 ALA A CA 1 ATOM 5056 C C . ALA A 1 622 ? 55.820 66.985 -31.144 1.00 10.53 ? 622 ALA A C 1 ATOM 5057 O O . ALA A 1 622 ? 54.709 66.462 -31.022 1.00 14.71 ? 622 ALA A O 1 ATOM 5058 C CB . ALA A 1 622 ? 56.122 68.945 -29.633 1.00 11.72 ? 622 ALA A CB 1 ATOM 5059 N N . ARG A 1 623 ? 56.937 66.304 -31.360 1.00 10.26 ? 623 ARG A N 1 ATOM 5060 C CA . ARG A 1 623 ? 56.943 64.814 -31.391 1.00 10.42 ? 623 ARG A CA 1 ATOM 5061 C C . ARG A 1 623 ? 57.961 64.402 -30.359 1.00 9.40 ? 623 ARG A C 1 ATOM 5062 O O . ARG A 1 623 ? 59.128 64.775 -30.420 1.00 11.30 ? 623 ARG A O 1 ATOM 5063 C CB . ARG A 1 623 ? 57.326 64.292 -32.793 1.00 13.40 ? 623 ARG A CB 1 ATOM 5064 C CG . ARG A 1 623 ? 57.346 62.772 -32.811 1.00 14.82 ? 623 ARG A CG 1 ATOM 5065 C CD . ARG A 1 623 ? 57.406 62.213 -34.292 1.00 17.61 ? 623 ARG A CD 1 ATOM 5066 N NE . ARG A 1 623 ? 57.597 60.753 -34.291 1.00 18.47 ? 623 ARG A NE 1 ATOM 5067 C CZ . ARG A 1 623 ? 58.801 60.184 -34.211 1.00 20.26 ? 623 ARG A CZ 1 ATOM 5068 N NH1 . ARG A 1 623 ? 59.903 60.902 -34.156 1.00 22.11 ? 623 ARG A NH1 1 ATOM 5069 N NH2 . ARG A 1 623 ? 58.881 58.863 -34.084 1.00 22.18 ? 623 ARG A NH2 1 ATOM 5070 N N . VAL A 1 624 ? 57.486 63.631 -29.379 1.00 9.62 ? 624 VAL A N 1 ATOM 5071 C CA . VAL A 1 624 ? 58.283 63.350 -28.182 1.00 9.52 ? 624 VAL A CA 1 ATOM 5072 C C . VAL A 1 624 ? 58.353 61.864 -27.880 1.00 8.92 ? 624 VAL A C 1 ATOM 5073 O O . VAL A 1 624 ? 57.316 61.185 -27.969 1.00 9.15 ? 624 VAL A O 1 ATOM 5074 C CB . VAL A 1 624 ? 57.644 64.119 -26.977 1.00 9.43 ? 624 VAL A CB 1 ATOM 5075 C CG1 . VAL A 1 624 ? 58.659 64.082 -25.783 1.00 9.80 ? 624 VAL A CG1 1 ATOM 5076 C CG2 . VAL A 1 624 ? 57.301 65.602 -27.397 1.00 10.69 ? 624 VAL A CG2 1 ATOM 5077 N N . PRO A 1 625 ? 59.568 61.374 -27.513 1.00 9.00 ? 625 PRO A N 1 ATOM 5078 C CA . PRO A 1 625 ? 59.684 59.927 -27.253 1.00 9.24 ? 625 PRO A CA 1 ATOM 5079 C C . PRO A 1 625 ? 58.866 59.464 -26.037 1.00 8.99 ? 625 PRO A C 1 ATOM 5080 O O . PRO A 1 625 ? 58.438 60.284 -25.187 1.00 8.83 ? 625 PRO A O 1 ATOM 5081 C CB . PRO A 1 625 ? 61.167 59.730 -26.915 1.00 11.12 ? 625 PRO A CB 1 ATOM 5082 C CG . PRO A 1 625 ? 61.897 60.945 -27.529 1.00 11.25 ? 625 PRO A CG 1 ATOM 5083 C CD . PRO A 1 625 ? 60.870 62.063 -27.398 1.00 9.61 ? 625 PRO A CD 1 ATOM 5084 N N . PRO A 1 626 ? 58.658 58.165 -25.898 1.00 9.03 ? 626 PRO A N 1 ATOM 5085 C CA . PRO A 1 626 ? 57.933 57.614 -24.724 1.00 8.06 ? 626 PRO A CA 1 ATOM 5086 C C . PRO A 1 626 ? 58.733 58.049 -23.463 1.00 7.79 ? 626 PRO A C 1 ATOM 5087 O O . PRO A 1 626 ? 59.956 57.872 -23.385 1.00 8.95 ? 626 PRO A O 1 ATOM 5088 C CB . PRO A 1 626 ? 58.118 56.100 -24.893 1.00 8.31 ? 626 PRO A CB 1 ATOM 5089 C CG . PRO A 1 626 ? 58.373 55.917 -26.401 1.00 9.09 ? 626 PRO A CG 1 ATOM 5090 C CD . PRO A 1 626 ? 59.247 57.103 -26.758 1.00 9.71 ? 626 PRO A CD 1 ATOM 5091 N N . MET A 1 627 ? 58.027 58.604 -22.463 1.00 7.59 ? 627 MET A N 1 ATOM 5092 C CA . MET A 1 627 ? 58.666 59.023 -21.183 1.00 7.49 ? 627 MET A CA 1 ATOM 5093 C C . MET A 1 627 ? 59.931 59.787 -21.449 1.00 7.64 ? 627 MET A C 1 ATOM 5094 O O . MET A 1 627 ? 60.965 59.630 -20.772 1.00 8.80 ? 627 MET A O 1 ATOM 5095 C CB . MET A 1 627 ? 58.980 57.791 -20.300 1.00 8.34 ? 627 MET A CB 1 ATOM 5096 C CG . MET A 1 627 ? 57.645 57.069 -19.904 1.00 8.77 ? 627 MET A CG 1 ATOM 5097 S SD . MET A 1 627 ? 57.872 55.383 -19.240 1.00 11.26 ? 627 MET A SD 1 ATOM 5098 C CE . MET A 1 627 ? 58.714 55.704 -17.783 1.00 12.11 ? 627 MET A CE 1 ATOM 5099 N N . GLY A 1 628 ? 59.825 60.683 -22.442 1.00 8.99 ? 628 GLY A N 1 ATOM 5100 C CA . GLY A 1 628 ? 61.018 61.360 -22.951 1.00 10.36 ? 628 GLY A CA 1 ATOM 5101 C C . GLY A 1 628 ? 60.946 62.850 -23.158 1.00 7.76 ? 628 GLY A C 1 ATOM 5102 O O . GLY A 1 628 ? 59.970 63.507 -22.716 1.00 8.36 ? 628 GLY A O 1 ATOM 5103 N N . LEU A 1 629 ? 61.986 63.392 -23.796 1.00 8.37 ? 629 LEU A N 1 ATOM 5104 C CA . LEU A 1 629 ? 62.114 64.864 -24.005 1.00 8.91 ? 629 LEU A CA 1 ATOM 5105 C C . LEU A 1 629 ? 62.502 65.148 -25.423 1.00 9.29 ? 629 LEU A C 1 ATOM 5106 O O . LEU A 1 629 ? 63.257 64.351 -26.063 1.00 9.51 ? 629 LEU A O 1 ATOM 5107 C CB . LEU A 1 629 ? 63.199 65.454 -23.093 1.00 8.88 ? 629 LEU A CB 1 ATOM 5108 C CG . LEU A 1 629 ? 62.963 65.300 -21.597 1.00 8.98 ? 629 LEU A CG 1 ATOM 5109 C CD1 . LEU A 1 629 ? 64.225 65.521 -20.792 1.00 9.66 ? 629 LEU A CD1 1 ATOM 5110 C CD2 . LEU A 1 629 ? 61.899 66.321 -21.147 1.00 9.23 ? 629 LEU A CD2 1 ATOM 5111 N N . ALA A 1 630 ? 62.041 66.282 -25.935 1.00 9.03 ? 630 ALA A N 1 ATOM 5112 C CA . ALA A 1 630 ? 62.425 66.705 -27.315 1.00 9.15 ? 630 ALA A CA 1 ATOM 5113 C C . ALA A 1 630 ? 62.664 68.212 -27.297 1.00 9.18 ? 630 ALA A C 1 ATOM 5114 O O . ALA A 1 630 ? 61.847 68.972 -26.753 1.00 10.00 ? 630 ALA A O 1 ATOM 5115 C CB . ALA A 1 630 ? 61.339 66.338 -28.321 1.00 11.18 ? 630 ALA A CB 1 ATOM 5116 N N . THR A 1 631 ? 63.774 68.639 -27.894 1.00 9.93 ? 631 THR A N 1 ATOM 5117 C CA . THR A 1 631 ? 64.169 70.077 -27.919 1.00 10.80 ? 631 THR A CA 1 ATOM 5118 C C . THR A 1 631 ? 63.908 70.738 -29.271 1.00 10.15 ? 631 THR A C 1 ATOM 5119 O O . THR A 1 631 ? 64.135 70.107 -30.313 1.00 11.45 ? 631 THR A O 1 ATOM 5120 C CB . THR A 1 631 ? 65.688 70.158 -27.648 1.00 10.97 ? 631 THR A CB 1 ATOM 5121 O OG1 . THR A 1 631 ? 65.960 69.460 -26.424 1.00 11.03 ? 631 THR A OG1 1 ATOM 5122 C CG2 . THR A 1 631 ? 66.200 71.616 -27.482 1.00 13.62 ? 631 THR A CG2 1 ATOM 5123 N N . TYR A 1 632 ? 63.387 71.951 -29.231 1.00 9.83 ? 632 TYR A N 1 ATOM 5124 C CA . TYR A 1 632 ? 63.139 72.747 -30.462 1.00 8.88 ? 632 TYR A CA 1 ATOM 5125 C C . TYR A 1 632 ? 63.723 74.130 -30.220 1.00 9.86 ? 632 TYR A C 1 ATOM 5126 O O . TYR A 1 632 ? 64.046 74.536 -29.115 1.00 9.94 ? 632 TYR A O 1 ATOM 5127 C CB . TYR A 1 632 ? 61.640 72.851 -30.791 1.00 11.16 ? 632 TYR A CB 1 ATOM 5128 C CG . TYR A 1 632 ? 60.997 71.534 -31.123 1.00 9.99 ? 632 TYR A CG 1 ATOM 5129 C CD1 . TYR A 1 632 ? 60.610 70.619 -30.120 1.00 10.62 ? 632 TYR A CD1 1 ATOM 5130 C CD2 . TYR A 1 632 ? 60.790 71.162 -32.469 1.00 11.09 ? 632 TYR A CD2 1 ATOM 5131 C CE1 . TYR A 1 632 ? 60.056 69.399 -30.472 1.00 11.58 ? 632 TYR A CE1 1 ATOM 5132 C CE2 . TYR A 1 632 ? 60.240 69.936 -32.829 1.00 12.27 ? 632 TYR A CE2 1 ATOM 5133 C CZ . TYR A 1 632 ? 59.881 69.058 -31.812 1.00 12.27 ? 632 TYR A CZ 1 ATOM 5134 O OH . TYR A 1 632 ? 59.331 67.813 -32.146 1.00 14.53 ? 632 TYR A OH 1 ATOM 5135 N N . VAL A 1 633 ? 63.852 74.840 -31.344 1.00 9.83 ? 633 VAL A N 1 ATOM 5136 C CA . VAL A 1 633 ? 64.412 76.188 -31.318 1.00 10.47 ? 633 VAL A CA 1 ATOM 5137 C C . VAL A 1 633 ? 63.470 77.149 -32.056 1.00 9.89 ? 633 VAL A C 1 ATOM 5138 O O . VAL A 1 633 ? 62.980 76.831 -33.146 1.00 11.38 ? 633 VAL A O 1 ATOM 5139 C CB . VAL A 1 633 ? 65.815 76.225 -32.033 1.00 11.73 ? 633 VAL A CB 1 ATOM 5140 C CG1 . VAL A 1 633 ? 66.406 77.623 -31.956 1.00 14.66 ? 633 VAL A CG1 1 ATOM 5141 C CG2 . VAL A 1 633 ? 66.749 75.196 -31.405 1.00 14.23 ? 633 VAL A CG2 1 ATOM 5142 N N . LEU A 1 634 ? 63.226 78.285 -31.437 1.00 9.90 ? 634 LEU A N 1 ATOM 5143 C CA . LEU A 1 634 ? 62.374 79.349 -32.028 1.00 10.67 ? 634 LEU A CA 1 ATOM 5144 C C . LEU A 1 634 ? 63.348 80.459 -32.407 1.00 11.58 ? 634 LEU A C 1 ATOM 5145 O O . LEU A 1 634 ? 64.116 80.929 -31.571 1.00 12.20 ? 634 LEU A O 1 ATOM 5146 C CB . LEU A 1 634 ? 61.354 79.901 -31.012 1.00 12.73 ? 634 LEU A CB 1 ATOM 5147 C CG . LEU A 1 634 ? 60.477 78.898 -30.263 1.00 20.53 ? 634 LEU A CG 1 ATOM 5148 C CD1 . LEU A 1 634 ? 59.335 79.676 -29.570 1.00 17.50 ? 634 LEU A CD1 1 ATOM 5149 C CD2 . LEU A 1 634 ? 59.973 77.797 -31.091 1.00 22.48 ? 634 LEU A CD2 1 ATOM 5150 N N . THR A 1 635 ? 63.274 80.885 -33.689 1.00 12.47 ? 635 THR A N 1 ATOM 5151 C CA . THR A 1 635 ? 64.222 81.907 -34.195 1.00 11.44 ? 635 THR A CA 1 ATOM 5152 C C . THR A 1 635 ? 63.457 83.061 -34.854 1.00 12.89 ? 635 THR A C 1 ATOM 5153 O O . THR A 1 635 ? 62.508 82.851 -35.608 1.00 13.60 ? 635 THR A O 1 ATOM 5154 C CB . THR A 1 635 ? 65.148 81.262 -35.269 1.00 12.99 ? 635 THR A CB 1 ATOM 5155 O OG1 . THR A 1 635 ? 65.838 80.137 -34.670 1.00 14.60 ? 635 THR A OG1 1 ATOM 5156 C CG2 . THR A 1 635 ? 66.224 82.271 -35.739 1.00 14.05 ? 635 THR A CG2 1 ATOM 5157 N N . ILE A 1 636 ? 63.902 84.275 -34.545 1.00 14.77 ? 636 ILE A N 1 ATOM 5158 C CA . ILE A 1 636 ? 63.211 85.432 -35.148 1.00 15.96 ? 636 ILE A CA 1 ATOM 5159 C C . ILE A 1 636 ? 63.821 85.766 -36.528 1.00 17.06 ? 636 ILE A C 1 ATOM 5160 O O . ILE A 1 636 ? 64.959 85.392 -36.819 1.00 16.16 ? 636 ILE A O 1 ATOM 5161 C CB . ILE A 1 636 ? 63.321 86.626 -34.234 1.00 15.48 ? 636 ILE A CB 1 ATOM 5162 C CG1 . ILE A 1 636 ? 62.355 87.747 -34.681 1.00 15.30 ? 636 ILE A CG1 1 ATOM 5163 C CG2 . ILE A 1 636 ? 64.764 87.151 -34.217 1.00 16.59 ? 636 ILE A CG2 1 ATOM 5164 C CD1 . ILE A 1 636 ? 62.324 88.949 -33.736 1.00 19.29 ? 636 ILE A CD1 1 ATOM 5165 N N . SER A 1 637 ? 62.989 86.328 -37.409 1.00 17.74 ? 637 SER A N 1 ATOM 5166 C CA . SER A 1 637 ? 63.500 86.800 -38.715 1.00 20.05 ? 637 SER A CA 1 ATOM 5167 C C . SER A 1 637 ? 62.848 88.163 -38.937 1.00 22.65 ? 637 SER A C 1 ATOM 5168 O O . SER A 1 637 ? 61.944 88.560 -38.217 1.00 21.03 ? 637 SER A O 1 ATOM 5169 C CB . SER A 1 637 ? 63.181 85.813 -39.861 1.00 25.36 ? 637 SER A CB 1 ATOM 5170 O OG . SER A 1 637 ? 61.803 85.548 -39.988 1.00 32.35 ? 637 SER A OG 1 ATOM 5171 N N . ASP A 1 638 ? 63.346 88.896 -39.933 1.00 26.62 ? 638 ASP A N 1 ATOM 5172 C CA . ASP A 1 638 ? 62.802 90.237 -40.185 1.00 29.84 ? 638 ASP A CA 1 ATOM 5173 C C . ASP A 1 638 ? 61.471 90.207 -40.947 1.00 28.87 ? 638 ASP A C 1 ATOM 5174 O O . ASP A 1 638 ? 60.721 91.183 -40.910 1.00 34.27 ? 638 ASP A O 1 ATOM 5175 C CB . ASP A 1 638 ? 63.830 91.091 -40.937 1.00 35.79 ? 638 ASP A CB 1 ATOM 5176 C CG . ASP A 1 638 ? 63.769 90.871 -42.430 1.00 44.50 ? 638 ASP A CG 1 ATOM 5177 O OD1 . ASP A 1 638 ? 63.797 89.684 -42.855 1.00 49.24 ? 638 ASP A OD1 1 ATOM 5178 O OD2 . ASP A 1 638 ? 63.689 91.879 -43.188 1.00 48.98 ? 638 ASP A OD2 1 ATOM 5179 N N . SER A 1 639 ? 61.149 89.081 -41.596 1.00 24.78 ? 639 SER A N 1 ATOM 5180 C CA . SER A 1 639 ? 59.914 88.977 -42.352 1.00 26.34 ? 639 SER A CA 1 ATOM 5181 C C . SER A 1 639 ? 59.306 87.587 -42.249 1.00 25.40 ? 639 SER A C 1 ATOM 5182 O O . SER A 1 639 ? 59.880 86.700 -41.591 1.00 22.92 ? 639 SER A O 1 ATOM 5183 C CB . SER A 1 639 ? 60.162 89.331 -43.830 1.00 24.14 ? 639 SER A CB 1 ATOM 5184 O OG . SER A 1 639 ? 60.983 88.358 -44.456 1.00 32.58 ? 639 SER A OG 1 ATOM 5185 N N . LYS A 1 640 ? 58.153 87.401 -42.874 1.00 23.41 ? 640 LYS A N 1 ATOM 5186 C CA . LYS A 1 640 ? 57.469 86.109 -42.845 1.00 24.68 ? 640 LYS A CA 1 ATOM 5187 C C . LYS A 1 640 ? 58.394 84.947 -43.198 1.00 23.11 ? 640 LYS A C 1 ATOM 5188 O O . LYS A 1 640 ? 58.949 84.856 -44.298 1.00 23.25 ? 640 LYS A O 1 ATOM 5189 C CB . LYS A 1 640 ? 56.257 86.089 -43.783 1.00 27.29 ? 640 LYS A CB 1 ATOM 5190 C CG . LYS A 1 640 ? 55.006 86.833 -43.293 1.00 35.72 ? 640 LYS A CG 1 ATOM 5191 C CD . LYS A 1 640 ? 53.789 86.568 -44.221 1.00 38.28 ? 640 LYS A CD 1 ATOM 5192 C CE . LYS A 1 640 ? 54.019 87.096 -45.631 1.00 42.58 ? 640 LYS A CE 1 ATOM 5193 N NZ . LYS A 1 640 ? 52.979 88.095 -46.035 1.00 46.09 ? 640 LYS A NZ 1 ATOM 5194 N N . PRO A 1 641 ? 58.566 84.008 -42.255 1.00 21.37 ? 641 PRO A N 1 ATOM 5195 C CA . PRO A 1 641 ? 59.410 82.835 -42.446 1.00 20.79 ? 641 PRO A CA 1 ATOM 5196 C C . PRO A 1 641 ? 58.752 81.850 -43.406 1.00 19.55 ? 641 PRO A C 1 ATOM 5197 O O . PRO A 1 641 ? 57.529 81.699 -43.445 1.00 19.37 ? 641 PRO A O 1 ATOM 5198 C CB . PRO A 1 641 ? 59.480 82.210 -41.029 1.00 23.24 ? 641 PRO A CB 1 ATOM 5199 C CG . PRO A 1 641 ? 59.114 83.270 -40.127 1.00 20.71 ? 641 PRO A CG 1 ATOM 5200 C CD . PRO A 1 641 ? 58.099 84.091 -40.855 1.00 20.90 ? 641 PRO A CD 1 ATOM 5201 N N . GLU A 1 642 ? 59.556 81.109 -44.142 1.00 19.11 ? 642 GLU A N 1 ATOM 5202 C CA . GLU A 1 642 ? 58.998 80.134 -45.064 1.00 19.07 ? 642 GLU A CA 1 ATOM 5203 C C . GLU A 1 642 ? 58.045 79.060 -44.517 1.00 19.73 ? 642 GLU A C 1 ATOM 5204 O O . GLU A 1 642 ? 57.062 78.683 -45.148 1.00 22.57 ? 642 GLU A O 1 ATOM 5205 C CB . GLU A 1 642 ? 60.140 79.405 -45.802 1.00 22.84 ? 642 GLU A CB 1 ATOM 5206 C CG . GLU A 1 642 ? 59.686 78.315 -46.745 1.00 28.43 ? 642 GLU A CG 1 ATOM 5207 C CD . GLU A 1 642 ? 60.866 77.690 -47.484 1.00 36.14 ? 642 GLU A CD 1 ATOM 5208 O OE1 . GLU A 1 642 ? 60.647 76.653 -48.160 1.00 42.06 ? 642 GLU A OE1 1 ATOM 5209 O OE2 . GLU A 1 642 ? 62.001 78.234 -47.376 1.00 37.33 ? 642 GLU A OE2 1 ATOM 5210 N N . HIS A 1 643 ? 58.336 78.564 -43.316 1.00 17.57 ? 643 HIS A N 1 ATOM 5211 C CA . HIS A 1 643 ? 57.530 77.463 -42.761 1.00 17.47 ? 643 HIS A CA 1 ATOM 5212 C C . HIS A 1 643 ? 56.560 77.882 -41.667 1.00 15.47 ? 643 HIS A C 1 ATOM 5213 O O . HIS A 1 643 ? 56.110 77.011 -40.895 1.00 15.59 ? 643 HIS A O 1 ATOM 5214 C CB . HIS A 1 643 ? 58.464 76.362 -42.232 1.00 18.29 ? 643 HIS A CB 1 ATOM 5215 C CG . HIS A 1 643 ? 59.327 75.751 -43.295 1.00 18.97 ? 643 HIS A CG 1 ATOM 5216 N ND1 . HIS A 1 643 ? 58.882 74.736 -44.110 1.00 27.08 ? 643 HIS A ND1 1 ATOM 5217 C CD2 . HIS A 1 643 ? 60.574 76.061 -43.716 1.00 22.20 ? 643 HIS A CD2 1 ATOM 5218 C CE1 . HIS A 1 643 ? 59.823 74.445 -45.001 1.00 22.74 ? 643 HIS A CE1 1 ATOM 5219 N NE2 . HIS A 1 643 ? 60.854 75.239 -44.781 1.00 22.11 ? 643 HIS A NE2 1 ATOM 5220 N N . THR A 1 644 ? 56.238 79.165 -41.589 1.00 13.20 ? 644 THR A N 1 ATOM 5221 C CA . THR A 1 644 ? 55.266 79.653 -40.623 1.00 14.29 ? 644 THR A CA 1 ATOM 5222 C C . THR A 1 644 ? 54.097 80.293 -41.380 1.00 15.99 ? 644 THR A C 1 ATOM 5223 O O . THR A 1 644 ? 54.339 81.126 -42.286 1.00 17.77 ? 644 THR A O 1 ATOM 5224 C CB . THR A 1 644 ? 55.933 80.634 -39.675 1.00 13.85 ? 644 THR A CB 1 ATOM 5225 O OG1 . THR A 1 644 ? 56.985 79.936 -38.964 1.00 14.93 ? 644 THR A OG1 1 ATOM 5226 C CG2 . THR A 1 644 ? 54.947 81.245 -38.636 1.00 13.71 ? 644 THR A CG2 1 ATOM 5227 N N . SER A 1 645 ? 52.861 79.935 -41.044 1.00 13.89 ? 645 SER A N 1 ATOM 5228 C CA . SER A 1 645 ? 51.666 80.512 -41.652 1.00 13.70 ? 645 SER A CA 1 ATOM 5229 C C . SER A 1 645 ? 50.961 81.350 -40.592 1.00 13.03 ? 645 SER A C 1 ATOM 5230 O O . SER A 1 645 ? 51.286 81.285 -39.400 1.00 13.75 ? 645 SER A O 1 ATOM 5231 C CB . SER A 1 645 ? 50.737 79.433 -42.199 1.00 14.54 ? 645 SER A CB 1 ATOM 5232 O OG . SER A 1 645 ? 50.222 78.659 -41.103 1.00 15.36 ? 645 SER A OG 1 ATOM 5233 N N . TYR A 1 646 ? 50.015 82.183 -41.008 1.00 12.97 ? 646 TYR A N 1 ATOM 5234 C CA . TYR A 1 646 ? 49.306 83.076 -40.123 1.00 11.49 ? 646 TYR A CA 1 ATOM 5235 C C . TYR A 1 646 ? 47.810 82.861 -40.206 1.00 12.83 ? 646 TYR A C 1 ATOM 5236 O O . TYR A 1 646 ? 47.267 82.827 -41.300 1.00 16.47 ? 646 TYR A O 1 ATOM 5237 C CB . TYR A 1 646 ? 49.612 84.538 -40.527 1.00 14.05 ? 646 TYR A CB 1 ATOM 5238 C CG . TYR A 1 646 ? 51.085 84.798 -40.291 1.00 13.03 ? 646 TYR A CG 1 ATOM 5239 C CD1 . TYR A 1 646 ? 52.016 84.537 -41.284 1.00 15.23 ? 646 TYR A CD1 1 ATOM 5240 C CD2 . TYR A 1 646 ? 51.549 85.165 -39.036 1.00 11.99 ? 646 TYR A CD2 1 ATOM 5241 C CE1 . TYR A 1 646 ? 53.415 84.636 -41.047 1.00 16.86 ? 646 TYR A CE1 1 ATOM 5242 C CE2 . TYR A 1 646 ? 52.956 85.281 -38.781 1.00 16.01 ? 646 TYR A CE2 1 ATOM 5243 C CZ . TYR A 1 646 ? 53.855 85.002 -39.811 1.00 16.49 ? 646 TYR A CZ 1 ATOM 5244 O OH . TYR A 1 646 ? 55.220 85.063 -39.583 1.00 19.28 ? 646 TYR A OH 1 ATOM 5245 N N . ALA A 1 647 ? 47.139 82.775 -39.051 1.00 12.18 ? 647 ALA A N 1 ATOM 5246 C CA . ALA A 1 647 ? 45.715 82.551 -39.033 1.00 12.05 ? 647 ALA A CA 1 ATOM 5247 C C . ALA A 1 647 ? 44.939 83.798 -39.486 1.00 12.71 ? 647 ALA A C 1 ATOM 5248 O O . ALA A 1 647 ? 45.354 84.912 -39.301 1.00 13.46 ? 647 ALA A O 1 ATOM 5249 C CB . ALA A 1 647 ? 45.267 82.174 -37.584 1.00 13.29 ? 647 ALA A CB 1 ATOM 5250 N N . SER A 1 648 ? 43.791 83.534 -40.073 1.00 12.78 ? 648 SER A N 1 ATOM 5251 C CA . SER A 1 648 ? 42.883 84.653 -40.338 1.00 12.68 ? 648 SER A CA 1 ATOM 5252 C C . SER A 1 648 ? 41.999 84.800 -39.121 1.00 12.61 ? 648 SER A C 1 ATOM 5253 O O . SER A 1 648 ? 41.826 83.843 -38.312 1.00 12.46 ? 648 SER A O 1 ATOM 5254 C CB . SER A 1 648 ? 42.031 84.348 -41.568 1.00 15.09 ? 648 SER A CB 1 ATOM 5255 O OG . SER A 1 648 ? 41.213 83.215 -41.369 1.00 20.04 ? 648 SER A OG 1 ATOM 5256 N N . ASN A 1 649 ? 41.368 85.952 -38.933 1.00 11.77 ? 649 ASN A N 1 ATOM 5257 C CA . ASN A 1 649 ? 40.508 86.228 -37.783 1.00 11.47 ? 649 ASN A CA 1 ATOM 5258 C C . ASN A 1 649 ? 39.305 86.996 -38.251 1.00 11.73 ? 649 ASN A C 1 ATOM 5259 O O . ASN A 1 649 ? 39.468 88.011 -39.016 1.00 12.74 ? 649 ASN A O 1 ATOM 5260 C CB . ASN A 1 649 ? 41.240 87.035 -36.716 1.00 11.79 ? 649 ASN A CB 1 ATOM 5261 C CG . ASN A 1 649 ? 42.475 86.296 -36.147 1.00 12.36 ? 649 ASN A CG 1 ATOM 5262 O OD1 . ASN A 1 649 ? 42.340 85.511 -35.176 1.00 13.00 ? 649 ASN A OD1 1 ATOM 5263 N ND2 . ASN A 1 649 ? 43.661 86.480 -36.753 1.00 13.14 ? 649 ASN A ND2 1 ATOM 5264 N N . LEU A 1 650 ? 38.142 86.581 -37.805 1.00 12.50 ? 650 LEU A N 1 ATOM 5265 C CA . LEU A 1 650 ? 36.850 87.172 -38.190 1.00 11.07 ? 650 LEU A CA 1 ATOM 5266 C C . LEU A 1 650 ? 36.042 87.442 -36.949 1.00 11.31 ? 650 LEU A C 1 ATOM 5267 O O . LEU A 1 650 ? 35.783 86.507 -36.168 1.00 12.84 ? 650 LEU A O 1 ATOM 5268 C CB . LEU A 1 650 ? 36.128 86.191 -39.135 1.00 12.23 ? 650 LEU A CB 1 ATOM 5269 C CG . LEU A 1 650 ? 34.675 86.565 -39.458 1.00 11.97 ? 650 LEU A CG 1 ATOM 5270 C CD1 . LEU A 1 650 ? 34.626 87.862 -40.343 1.00 13.52 ? 650 LEU A CD1 1 ATOM 5271 C CD2 . LEU A 1 650 ? 34.026 85.413 -40.242 1.00 16.33 ? 650 LEU A CD2 1 ATOM 5272 N N . LEU A 1 651 ? 35.690 88.681 -36.668 1.00 12.90 ? 651 LEU A N 1 ATOM 5273 C CA . LEU A 1 651 ? 34.903 89.074 -35.530 1.00 12.18 ? 651 LEU A CA 1 ATOM 5274 C C . LEU A 1 651 ? 33.452 89.320 -35.978 1.00 13.46 ? 651 LEU A C 1 ATOM 5275 O O . LEU A 1 651 ? 33.194 90.219 -36.818 1.00 15.59 ? 651 LEU A O 1 ATOM 5276 C CB . LEU A 1 651 ? 35.532 90.326 -34.921 1.00 15.89 ? 651 LEU A CB 1 ATOM 5277 C CG . LEU A 1 651 ? 35.174 90.667 -33.455 1.00 22.18 ? 651 LEU A CG 1 ATOM 5278 C CD1 . LEU A 1 651 ? 33.832 91.275 -33.349 1.00 28.44 ? 651 LEU A CD1 1 ATOM 5279 C CD2 . LEU A 1 651 ? 35.263 89.449 -32.618 1.00 19.47 ? 651 LEU A CD2 1 ATOM 5280 N N . LEU A 1 652 ? 32.509 88.521 -35.511 1.00 13.11 ? 652 LEU A N 1 ATOM 5281 C CA . LEU A 1 652 ? 31.118 88.598 -35.886 1.00 13.32 ? 652 LEU A CA 1 ATOM 5282 C C . LEU A 1 652 ? 30.352 89.289 -34.791 1.00 16.16 ? 652 LEU A C 1 ATOM 5283 O O . LEU A 1 652 ? 30.245 88.810 -33.632 1.00 15.54 ? 652 LEU A O 1 ATOM 5284 C CB . LEU A 1 652 ? 30.574 87.200 -36.175 1.00 13.79 ? 652 LEU A CB 1 ATOM 5285 C CG . LEU A 1 652 ? 31.351 86.498 -37.285 1.00 14.25 ? 652 LEU A CG 1 ATOM 5286 C CD1 . LEU A 1 652 ? 30.815 85.071 -37.482 1.00 15.54 ? 652 LEU A CD1 1 ATOM 5287 C CD2 . LEU A 1 652 ? 31.235 87.284 -38.648 1.00 15.77 ? 652 LEU A CD2 1 ATOM 5288 N N . ARG A 1 653 ? 29.786 90.454 -35.126 1.00 15.70 ? 653 ARG A N 1 ATOM 5289 C CA . ARG A 1 653 ? 29.038 91.239 -34.170 1.00 17.95 ? 653 ARG A CA 1 ATOM 5290 C C . ARG A 1 653 ? 28.440 92.436 -34.911 1.00 18.38 ? 653 ARG A C 1 ATOM 5291 O O . ARG A 1 653 ? 28.959 92.852 -35.921 1.00 19.93 ? 653 ARG A O 1 ATOM 5292 C CB . ARG A 1 653 ? 29.953 91.747 -33.054 1.00 18.49 ? 653 ARG A CB 1 ATOM 5293 C CG . ARG A 1 653 ? 30.934 92.757 -33.470 1.00 20.65 ? 653 ARG A CG 1 ATOM 5294 C CD . ARG A 1 653 ? 30.583 93.899 -32.638 1.00 33.08 ? 653 ARG A CD 1 ATOM 5295 N NE . ARG A 1 653 ? 31.479 93.985 -31.520 1.00 27.75 ? 653 ARG A NE 1 ATOM 5296 C CZ . ARG A 1 653 ? 31.208 94.573 -30.352 1.00 31.30 ? 653 ARG A CZ 1 ATOM 5297 N NH1 . ARG A 1 653 ? 30.032 95.123 -30.094 1.00 35.81 ? 653 ARG A NH1 1 ATOM 5298 N NH2 . ARG A 1 653 ? 32.175 94.696 -29.466 1.00 36.97 ? 653 ARG A NH2 1 ATOM 5299 N N . LYS A 1 654 ? 27.349 92.962 -34.397 1.00 22.12 ? 654 LYS A N 1 ATOM 5300 C CA . LYS A 1 654 ? 26.834 94.176 -35.023 1.00 25.78 ? 654 LYS A CA 1 ATOM 5301 C C . LYS A 1 654 ? 27.664 95.325 -34.376 1.00 26.17 ? 654 LYS A C 1 ATOM 5302 O O . LYS A 1 654 ? 28.154 95.201 -33.259 1.00 28.53 ? 654 LYS A O 1 ATOM 5303 C CB . LYS A 1 654 ? 25.361 94.368 -34.665 1.00 28.99 ? 654 LYS A CB 1 ATOM 5304 C CG . LYS A 1 654 ? 24.438 93.240 -35.119 1.00 33.35 ? 654 LYS A CG 1 ATOM 5305 C CD . LYS A 1 654 ? 23.266 93.785 -35.910 1.00 40.46 ? 654 LYS A CD 1 ATOM 5306 C CE . LYS A 1 654 ? 23.755 94.525 -37.154 1.00 41.72 ? 654 LYS A CE 1 ATOM 5307 N NZ . LYS A 1 654 ? 22.631 95.148 -37.937 1.00 46.02 ? 654 LYS A NZ 1 ATOM 5308 N N . ASN A 1 655 ? 27.807 96.444 -35.054 1.00 28.22 ? 655 ASN A N 1 ATOM 5309 C CA . ASN A 1 655 ? 28.537 97.559 -34.424 1.00 28.85 ? 655 ASN A CA 1 ATOM 5310 C C . ASN A 1 655 ? 30.005 97.241 -34.043 1.00 25.00 ? 655 ASN A C 1 ATOM 5311 O O . ASN A 1 655 ? 30.432 97.440 -32.915 1.00 27.89 ? 655 ASN A O 1 ATOM 5312 C CB . ASN A 1 655 ? 27.785 97.993 -33.157 1.00 29.74 ? 655 ASN A CB 1 ATOM 5313 C CG . ASN A 1 655 ? 28.283 99.316 -32.602 1.00 38.10 ? 655 ASN A CG 1 ATOM 5314 O OD1 . ASN A 1 655 ? 28.131 99.597 -31.399 1.00 36.13 ? 655 ASN A OD1 1 ATOM 5315 N ND2 . ASN A 1 655 ? 28.864 100.158 -33.479 1.00 34.78 ? 655 ASN A ND2 1 ATOM 5316 N N . PRO A 1 656 ? 30.796 96.760 -34.997 1.00 21.40 ? 656 PRO A N 1 ATOM 5317 C CA . PRO A 1 656 ? 32.200 96.445 -34.693 1.00 19.45 ? 656 PRO A CA 1 ATOM 5318 C C . PRO A 1 656 ? 33.054 97.701 -34.705 1.00 19.23 ? 656 PRO A C 1 ATOM 5319 O O . PRO A 1 656 ? 32.704 98.749 -35.279 1.00 18.79 ? 656 PRO A O 1 ATOM 5320 C CB . PRO A 1 656 ? 32.605 95.542 -35.845 1.00 19.04 ? 656 PRO A CB 1 ATOM 5321 C CG . PRO A 1 656 ? 31.805 96.190 -37.004 1.00 17.91 ? 656 PRO A CG 1 ATOM 5322 C CD . PRO A 1 656 ? 30.450 96.359 -36.372 1.00 20.35 ? 656 PRO A CD 1 ATOM 5323 N N . THR A 1 657 ? 34.188 97.586 -34.031 1.00 18.98 ? 657 THR A N 1 ATOM 5324 C CA . THR A 1 657 ? 35.170 98.643 -34.044 1.00 18.47 ? 657 THR A CA 1 ATOM 5325 C C . THR A 1 657 ? 36.466 97.923 -34.442 1.00 19.79 ? 657 THR A C 1 ATOM 5326 O O . THR A 1 657 ? 36.606 96.682 -34.298 1.00 21.35 ? 657 THR A O 1 ATOM 5327 C CB . THR A 1 657 ? 35.328 99.302 -32.669 1.00 22.31 ? 657 THR A CB 1 ATOM 5328 O OG1 . THR A 1 657 ? 35.400 98.287 -31.660 1.00 25.81 ? 657 THR A OG1 1 ATOM 5329 C CG2 . THR A 1 657 ? 34.129 100.217 -32.356 1.00 23.38 ? 657 THR A CG2 1 ATOM 5330 N N . SER A 1 658 ? 37.437 98.684 -34.891 1.00 17.04 ? 658 SER A N 1 ATOM 5331 C CA . SER A 1 658 ? 38.699 98.157 -35.381 1.00 18.37 ? 658 SER A CA 1 ATOM 5332 C C . SER A 1 658 ? 39.454 97.348 -34.316 1.00 18.45 ? 658 SER A C 1 ATOM 5333 O O . SER A 1 658 ? 39.252 97.527 -33.111 1.00 20.81 ? 658 SER A O 1 ATOM 5334 C CB . SER A 1 658 ? 39.542 99.321 -35.831 1.00 22.55 ? 658 SER A CB 1 ATOM 5335 O OG . SER A 1 658 ? 39.913 100.049 -34.664 1.00 24.52 ? 658 SER A OG 1 ATOM 5336 N N . LEU A 1 659 ? 40.324 96.445 -34.792 1.00 17.72 ? 659 LEU A N 1 ATOM 5337 C CA . LEU A 1 659 ? 41.120 95.568 -33.880 1.00 20.05 ? 659 LEU A CA 1 ATOM 5338 C C . LEU A 1 659 ? 42.530 95.422 -34.501 1.00 20.11 ? 659 LEU A C 1 ATOM 5339 O O . LEU A 1 659 ? 42.825 94.441 -35.202 1.00 20.51 ? 659 LEU A O 1 ATOM 5340 C CB . LEU A 1 659 ? 40.475 94.156 -33.787 1.00 22.22 ? 659 LEU A CB 1 ATOM 5341 C CG . LEU A 1 659 ? 39.168 94.005 -32.987 1.00 22.94 ? 659 LEU A CG 1 ATOM 5342 C CD1 . LEU A 1 659 ? 38.506 92.617 -33.211 1.00 24.84 ? 659 LEU A CD1 1 ATOM 5343 C CD2 . LEU A 1 659 ? 39.448 94.179 -31.553 1.00 23.18 ? 659 LEU A CD2 1 ATOM 5344 N N . PRO A 1 660 ? 43.393 96.426 -34.308 1.00 20.54 ? 660 PRO A N 1 ATOM 5345 C CA . PRO A 1 660 ? 44.763 96.398 -34.843 1.00 20.61 ? 660 PRO A CA 1 ATOM 5346 C C . PRO A 1 660 ? 45.580 95.318 -34.095 1.00 17.96 ? 660 PRO A C 1 ATOM 5347 O O . PRO A 1 660 ? 45.328 95.046 -32.914 1.00 20.01 ? 660 PRO A O 1 ATOM 5348 C CB . PRO A 1 660 ? 45.266 97.823 -34.597 1.00 22.79 ? 660 PRO A CB 1 ATOM 5349 C CG . PRO A 1 660 ? 44.574 98.229 -33.349 1.00 23.10 ? 660 PRO A CG 1 ATOM 5350 C CD . PRO A 1 660 ? 43.131 97.641 -33.522 1.00 21.55 ? 660 PRO A CD 1 ATOM 5351 N N . LEU A 1 661 ? 46.533 94.733 -34.794 1.00 20.80 ? 661 LEU A N 1 ATOM 5352 C CA . LEU A 1 661 ? 47.312 93.642 -34.164 1.00 19.55 ? 661 LEU A CA 1 ATOM 5353 C C . LEU A 1 661 ? 48.849 93.850 -34.320 1.00 24.30 ? 661 LEU A C 1 ATOM 5354 O O . LEU A 1 661 ? 49.608 92.871 -34.423 1.00 19.82 ? 661 LEU A O 1 ATOM 5355 C CB . LEU A 1 661 ? 46.871 92.338 -34.840 1.00 20.36 ? 661 LEU A CB 1 ATOM 5356 C CG . LEU A 1 661 ? 45.421 91.890 -34.597 1.00 15.41 ? 661 LEU A CG 1 ATOM 5357 C CD1 . LEU A 1 661 ? 45.191 90.594 -35.396 1.00 15.98 ? 661 LEU A CD1 1 ATOM 5358 C CD2 . LEU A 1 661 ? 45.213 91.657 -33.078 1.00 19.08 ? 661 LEU A CD2 1 ATOM 5359 N N . GLY A 1 662 ? 49.308 95.106 -34.378 1.00 23.31 ? 662 GLY A N 1 ATOM 5360 C CA . GLY A 1 662 ? 50.750 95.359 -34.541 1.00 22.37 ? 662 GLY A CA 1 ATOM 5361 C C . GLY A 1 662 ? 51.321 94.782 -35.819 1.00 22.28 ? 662 GLY A C 1 ATOM 5362 O O . GLY A 1 662 ? 50.747 94.925 -36.906 1.00 25.83 ? 662 GLY A O 1 ATOM 5363 N N . GLN A 1 663 ? 52.427 94.024 -35.681 1.00 22.90 ? 663 GLN A N 1 ATOM 5364 C CA . GLN A 1 663 ? 53.083 93.432 -36.841 1.00 24.72 ? 663 GLN A CA 1 ATOM 5365 C C . GLN A 1 663 ? 52.402 92.214 -37.455 1.00 18.45 ? 663 GLN A C 1 ATOM 5366 O O . GLN A 1 663 ? 52.795 91.733 -38.525 1.00 24.26 ? 663 GLN A O 1 ATOM 5367 C CB . GLN A 1 663 ? 54.522 93.044 -36.489 1.00 28.59 ? 663 GLN A CB 1 ATOM 5368 C CG . GLN A 1 663 ? 55.262 93.949 -35.476 1.00 35.10 ? 663 GLN A CG 1 ATOM 5369 C CD . GLN A 1 663 ? 56.565 93.256 -35.039 1.00 35.79 ? 663 GLN A CD 1 ATOM 5370 O OE1 . GLN A 1 663 ? 57.433 92.972 -35.895 1.00 32.90 ? 663 GLN A OE1 1 ATOM 5371 N NE2 . GLN A 1 663 ? 56.688 92.937 -33.727 1.00 34.26 ? 663 GLN A NE2 1 ATOM 5372 N N . TYR A 1 664 ? 51.343 91.735 -36.808 1.00 23.78 ? 664 TYR A N 1 ATOM 5373 C CA . TYR A 1 664 ? 50.629 90.567 -37.320 1.00 22.29 ? 664 TYR A CA 1 ATOM 5374 C C . TYR A 1 664 ? 50.288 90.854 -38.785 1.00 19.90 ? 664 TYR A C 1 ATOM 5375 O O . TYR A 1 664 ? 49.626 91.873 -39.082 1.00 24.19 ? 664 TYR A O 1 ATOM 5376 C CB . TYR A 1 664 ? 49.407 90.338 -36.420 1.00 21.59 ? 664 TYR A CB 1 ATOM 5377 C CG . TYR A 1 664 ? 48.786 88.991 -36.641 1.00 17.02 ? 664 TYR A CG 1 ATOM 5378 C CD1 . TYR A 1 664 ? 49.327 87.816 -36.049 1.00 15.37 ? 664 TYR A CD1 1 ATOM 5379 C CD2 . TYR A 1 664 ? 47.677 88.866 -37.458 1.00 14.74 ? 664 TYR A CD2 1 ATOM 5380 C CE1 . TYR A 1 664 ? 48.766 86.602 -36.285 1.00 14.22 ? 664 TYR A CE1 1 ATOM 5381 C CE2 . TYR A 1 664 ? 47.087 87.624 -37.700 1.00 16.57 ? 664 TYR A CE2 1 ATOM 5382 C CZ . TYR A 1 664 ? 47.652 86.488 -37.094 1.00 13.76 ? 664 TYR A CZ 1 ATOM 5383 O OH . TYR A 1 664 ? 47.009 85.285 -37.296 1.00 13.85 ? 664 TYR A OH 1 ATOM 5384 N N . PRO A 1 665 ? 50.656 89.963 -39.717 1.00 23.65 ? 665 PRO A N 1 ATOM 5385 C CA . PRO A 1 665 ? 50.413 90.179 -41.148 1.00 23.55 ? 665 PRO A CA 1 ATOM 5386 C C . PRO A 1 665 ? 49.056 90.051 -41.831 1.00 25.43 ? 665 PRO A C 1 ATOM 5387 O O . PRO A 1 665 ? 48.939 90.295 -43.031 1.00 27.99 ? 665 PRO A O 1 ATOM 5388 C CB . PRO A 1 665 ? 51.471 89.273 -41.803 1.00 24.46 ? 665 PRO A CB 1 ATOM 5389 C CG . PRO A 1 665 ? 51.524 88.113 -40.841 1.00 23.45 ? 665 PRO A CG 1 ATOM 5390 C CD . PRO A 1 665 ? 51.523 88.781 -39.503 1.00 20.80 ? 665 PRO A CD 1 ATOM 5391 N N A GLU A 1 666 ? 48.019 89.688 -41.096 0.50 22.42 ? 666 GLU A N 1 ATOM 5392 N N B GLU A 1 666 ? 48.055 89.660 -41.119 0.50 23.20 ? 666 GLU A N 1 ATOM 5393 C CA A GLU A 1 666 ? 46.696 89.524 -41.717 0.50 21.55 ? 666 GLU A CA 1 ATOM 5394 C CA B GLU A 1 666 ? 46.717 89.544 -41.686 0.50 22.73 ? 666 GLU A CA 1 ATOM 5395 C C A GLU A 1 666 ? 45.780 90.415 -40.927 0.50 20.32 ? 666 GLU A C 1 ATOM 5396 C C B GLU A 1 666 ? 45.723 90.423 -40.935 0.50 21.62 ? 666 GLU A C 1 ATOM 5397 O O A GLU A 1 666 ? 45.736 90.338 -39.695 0.50 18.90 ? 666 GLU A O 1 ATOM 5398 O O B GLU A 1 666 ? 45.736 90.338 -39.695 0.50 20.06 ? 666 GLU A O 1 ATOM 5399 C CB A GLU A 1 666 ? 46.230 88.074 -41.580 0.50 23.41 ? 666 GLU A CB 1 ATOM 5400 C CB B GLU A 1 666 ? 46.255 88.086 -41.674 0.50 24.78 ? 666 GLU A CB 1 ATOM 5401 C CG A GLU A 1 666 ? 44.724 87.838 -41.747 0.50 30.44 ? 666 GLU A CG 1 ATOM 5402 C CG B GLU A 1 666 ? 47.004 87.190 -42.647 0.50 31.09 ? 666 GLU A CG 1 ATOM 5403 C CD A GLU A 1 666 ? 44.355 87.061 -43.028 0.50 30.76 ? 666 GLU A CD 1 ATOM 5404 C CD B GLU A 1 666 ? 46.633 87.460 -44.092 0.50 31.25 ? 666 GLU A CD 1 ATOM 5405 O OE1 A GLU A 1 666 ? 45.272 86.636 -43.768 0.50 36.81 ? 666 GLU A OE1 1 ATOM 5406 O OE1 B GLU A 1 666 ? 45.431 87.653 -44.371 0.50 34.77 ? 666 GLU A OE1 1 ATOM 5407 O OE2 A GLU A 1 666 ? 43.155 86.875 -43.312 0.50 29.15 ? 666 GLU A OE2 1 ATOM 5408 O OE2 B GLU A 1 666 ? 47.545 87.478 -44.946 0.50 37.32 ? 666 GLU A OE2 1 ATOM 5409 N N . ASP A 1 667 ? 45.042 91.275 -41.643 1.00 18.90 ? 667 ASP A N 1 ATOM 5410 C CA . ASP A 1 667 ? 44.102 92.175 -40.962 1.00 19.18 ? 667 ASP A CA 1 ATOM 5411 C C . ASP A 1 667 ? 42.806 91.417 -40.485 1.00 12.03 ? 667 ASP A C 1 ATOM 5412 O O . ASP A 1 667 ? 42.305 90.590 -41.208 1.00 15.77 ? 667 ASP A O 1 ATOM 5413 C CB . ASP A 1 667 ? 43.593 93.270 -41.947 1.00 20.70 ? 667 ASP A CB 1 ATOM 5414 C CG . ASP A 1 667 ? 44.685 94.250 -42.368 1.00 28.03 ? 667 ASP A CG 1 ATOM 5415 O OD1 . ASP A 1 667 ? 45.681 94.427 -41.613 1.00 31.51 ? 667 ASP A OD1 1 ATOM 5416 O OD2 . ASP A 1 667 ? 44.520 94.882 -43.441 1.00 30.30 ? 667 ASP A OD2 1 ATOM 5417 N N . VAL A 1 668 ? 42.349 91.773 -39.330 1.00 13.30 ? 668 VAL A N 1 ATOM 5418 C CA . VAL A 1 668 ? 41.087 91.212 -38.813 1.00 14.85 ? 668 VAL A CA 1 ATOM 5419 C C . VAL A 1 668 ? 39.924 91.590 -39.726 1.00 14.96 ? 668 VAL A C 1 ATOM 5420 O O . VAL A 1 668 ? 39.892 92.757 -40.204 1.00 15.33 ? 668 VAL A O 1 ATOM 5421 C CB . VAL A 1 668 ? 40.781 91.701 -37.386 1.00 16.41 ? 668 VAL A CB 1 ATOM 5422 C CG1 . VAL A 1 668 ? 39.418 91.106 -36.897 1.00 15.74 ? 668 VAL A CG1 1 ATOM 5423 C CG2 . VAL A 1 668 ? 41.935 91.258 -36.409 1.00 17.22 ? 668 VAL A CG2 1 ATOM 5424 N N A LYS A 1 669 ? 39.028 90.661 -40.013 0.50 13.13 ? 669 LYS A N 1 ATOM 5425 N N B LYS A 1 669 ? 39.028 90.661 -40.013 0.50 13.42 ? 669 LYS A N 1 ATOM 5426 C CA A LYS A 1 669 ? 37.817 90.897 -40.833 0.50 13.49 ? 669 LYS A CA 1 ATOM 5427 C CA B LYS A 1 669 ? 37.817 90.897 -40.833 0.50 13.92 ? 669 LYS A CA 1 ATOM 5428 C C A LYS A 1 669 ? 36.633 90.971 -39.878 0.50 13.69 ? 669 LYS A C 1 ATOM 5429 C C B LYS A 1 669 ? 36.633 90.971 -39.878 0.50 14.15 ? 669 LYS A C 1 ATOM 5430 O O A LYS A 1 669 ? 36.666 90.386 -38.740 0.50 12.85 ? 669 LYS A O 1 ATOM 5431 O O B LYS A 1 669 ? 36.666 90.386 -38.740 0.50 13.57 ? 669 LYS A O 1 ATOM 5432 C CB A LYS A 1 669 ? 37.639 89.770 -41.810 0.50 18.08 ? 669 LYS A CB 1 ATOM 5433 C CB B LYS A 1 669 ? 37.639 89.770 -41.810 0.50 18.60 ? 669 LYS A CB 1 ATOM 5434 C CG A LYS A 1 669 ? 38.799 89.583 -42.790 0.50 26.00 ? 669 LYS A CG 1 ATOM 5435 C CG B LYS A 1 669 ? 38.799 89.583 -42.790 0.50 26.56 ? 669 LYS A CG 1 ATOM 5436 C CD A LYS A 1 669 ? 39.115 90.881 -43.540 0.50 30.36 ? 669 LYS A CD 1 ATOM 5437 C CD B LYS A 1 669 ? 39.115 90.881 -43.540 0.50 30.92 ? 669 LYS A CD 1 ATOM 5438 C CE A LYS A 1 669 ? 40.171 90.641 -44.644 0.50 32.94 ? 669 LYS A CE 1 ATOM 5439 N NZ A LYS A 1 669 ? 41.486 90.213 -44.025 0.50 32.15 ? 669 LYS A NZ 1 ATOM 5440 N NZ B LYS A 1 669 ? 39.493 90.481 -45.990 0.50 33.62 ? 669 LYS A NZ 1 ATOM 5441 N N . PHE A 1 670 ? 35.538 91.593 -40.321 1.00 13.84 ? 670 PHE A N 1 ATOM 5442 C CA . PHE A 1 670 ? 34.346 91.797 -39.511 1.00 13.53 ? 670 PHE A CA 1 ATOM 5443 C C . PHE A 1 670 ? 33.107 91.388 -40.292 1.00 15.25 ? 670 PHE A C 1 ATOM 5444 O O . PHE A 1 670 ? 33.124 91.312 -41.516 1.00 15.75 ? 670 PHE A O 1 ATOM 5445 C CB . PHE A 1 670 ? 34.192 93.296 -39.051 1.00 14.63 ? 670 PHE A CB 1 ATOM 5446 C CG . PHE A 1 670 ? 35.355 93.795 -38.254 1.00 13.40 ? 670 PHE A CG 1 ATOM 5447 C CD1 . PHE A 1 670 ? 36.489 94.267 -38.931 1.00 17.11 ? 670 PHE A CD1 1 ATOM 5448 C CD2 . PHE A 1 670 ? 35.389 93.711 -36.868 1.00 17.23 ? 670 PHE A CD2 1 ATOM 5449 C CE1 . PHE A 1 670 ? 37.660 94.636 -38.227 1.00 17.10 ? 670 PHE A CE1 1 ATOM 5450 C CE2 . PHE A 1 670 ? 36.541 94.080 -36.155 1.00 18.09 ? 670 PHE A CE2 1 ATOM 5451 C CZ . PHE A 1 670 ? 37.691 94.545 -36.858 1.00 17.24 ? 670 PHE A CZ 1 ATOM 5452 N N . GLY A 1 671 ? 32.034 91.067 -39.586 1.00 14.64 ? 671 GLY A N 1 ATOM 5453 C CA . GLY A 1 671 ? 30.785 90.710 -40.259 1.00 13.36 ? 671 GLY A CA 1 ATOM 5454 C C . GLY A 1 671 ? 29.668 90.640 -39.252 1.00 14.30 ? 671 GLY A C 1 ATOM 5455 O O . GLY A 1 671 ? 29.871 90.621 -38.039 1.00 13.34 ? 671 GLY A O 1 ATOM 5456 N N . ASP A 1 672 ? 28.445 90.654 -39.758 1.00 15.01 ? 672 ASP A N 1 ATOM 5457 C CA . ASP A 1 672 ? 27.311 90.503 -38.874 1.00 14.89 ? 672 ASP A CA 1 ATOM 5458 C C . ASP A 1 672 ? 27.242 88.989 -38.432 1.00 14.29 ? 672 ASP A C 1 ATOM 5459 O O . ASP A 1 672 ? 27.752 88.113 -39.142 1.00 15.45 ? 672 ASP A O 1 ATOM 5460 C CB . ASP A 1 672 ? 25.994 90.761 -39.627 1.00 18.38 ? 672 ASP A CB 1 ATOM 5461 C CG . ASP A 1 672 ? 25.675 92.245 -39.806 1.00 23.15 ? 672 ASP A CG 1 ATOM 5462 O OD1 . ASP A 1 672 ? 26.353 93.098 -39.223 1.00 26.35 ? 672 ASP A OD1 1 ATOM 5463 O OD2 . ASP A 1 672 ? 24.679 92.517 -40.543 1.00 29.51 ? 672 ASP A OD2 1 ATOM 5464 N N . PRO A 1 673 ? 26.672 88.716 -37.230 1.00 14.59 ? 673 PRO A N 1 ATOM 5465 C CA . PRO A 1 673 ? 26.558 87.304 -36.807 1.00 16.37 ? 673 PRO A CA 1 ATOM 5466 C C . PRO A 1 673 ? 25.963 86.457 -37.928 1.00 18.00 ? 673 PRO A C 1 ATOM 5467 O O . PRO A 1 673 ? 25.054 86.908 -38.640 1.00 18.16 ? 673 PRO A O 1 ATOM 5468 C CB . PRO A 1 673 ? 25.603 87.387 -35.628 1.00 17.53 ? 673 PRO A CB 1 ATOM 5469 C CG . PRO A 1 673 ? 26.017 88.680 -34.963 1.00 20.56 ? 673 PRO A CG 1 ATOM 5470 C CD . PRO A 1 673 ? 26.095 89.611 -36.200 1.00 16.56 ? 673 PRO A CD 1 ATOM 5471 N N . ARG A 1 674 ? 26.473 85.245 -38.077 1.00 16.36 ? 674 ARG A N 1 ATOM 5472 C CA . ARG A 1 674 ? 25.993 84.307 -39.122 1.00 14.45 ? 674 ARG A CA 1 ATOM 5473 C C . ARG A 1 674 ? 26.470 82.906 -38.764 1.00 15.07 ? 674 ARG A C 1 ATOM 5474 O O . ARG A 1 674 ? 27.434 82.751 -37.993 1.00 15.36 ? 674 ARG A O 1 ATOM 5475 C CB . ARG A 1 674 ? 26.570 84.661 -40.522 1.00 16.00 ? 674 ARG A CB 1 ATOM 5476 C CG . ARG A 1 674 ? 28.094 84.604 -40.653 1.00 18.39 ? 674 ARG A CG 1 ATOM 5477 C CD . ARG A 1 674 ? 28.480 84.744 -42.124 1.00 19.72 ? 674 ARG A CD 1 ATOM 5478 N NE . ARG A 1 674 ? 29.854 84.431 -42.465 1.00 24.81 ? 674 ARG A NE 1 ATOM 5479 C CZ . ARG A 1 674 ? 30.824 85.322 -42.619 1.00 25.68 ? 674 ARG A CZ 1 ATOM 5480 N NH1 . ARG A 1 674 ? 30.595 86.642 -42.438 1.00 26.63 ? 674 ARG A NH1 1 ATOM 5481 N NH2 . ARG A 1 674 ? 32.029 84.863 -43.018 1.00 27.34 ? 674 ARG A NH2 1 ATOM 5482 N N . GLU A 1 675 ? 25.827 81.894 -39.311 1.00 16.25 ? 675 GLU A N 1 ATOM 5483 C CA . GLU A 1 675 ? 26.336 80.542 -39.131 1.00 14.83 ? 675 GLU A CA 1 ATOM 5484 C C . GLU A 1 675 ? 27.686 80.344 -39.862 1.00 16.72 ? 675 GLU A C 1 ATOM 5485 O O . GLU A 1 675 ? 27.986 80.964 -40.920 1.00 19.12 ? 675 GLU A O 1 ATOM 5486 C CB . GLU A 1 675 ? 25.311 79.532 -39.641 1.00 18.96 ? 675 GLU A CB 1 ATOM 5487 C CG . GLU A 1 675 ? 24.053 79.668 -38.877 1.00 19.54 ? 675 GLU A CG 1 ATOM 5488 C CD . GLU A 1 675 ? 23.176 78.431 -38.880 1.00 30.73 ? 675 GLU A CD 1 ATOM 5489 O OE1 . GLU A 1 675 ? 23.327 77.618 -39.830 1.00 33.56 ? 675 GLU A OE1 1 ATOM 5490 O OE2 . GLU A 1 675 ? 22.341 78.297 -37.923 1.00 34.55 ? 675 GLU A OE2 1 ATOM 5491 N N . ILE A 1 676 ? 28.545 79.487 -39.311 1.00 15.97 ? 676 ILE A N 1 ATOM 5492 C CA . ILE A 1 676 ? 29.785 79.220 -39.960 1.00 18.08 ? 676 ILE A CA 1 ATOM 5493 C C . ILE A 1 676 ? 30.171 77.751 -39.810 1.00 15.47 ? 676 ILE A C 1 ATOM 5494 O O . ILE A 1 676 ? 29.652 77.053 -38.908 1.00 16.94 ? 676 ILE A O 1 ATOM 5495 C CB . ILE A 1 676 ? 30.908 80.073 -39.462 1.00 22.88 ? 676 ILE A CB 1 ATOM 5496 C CG1 . ILE A 1 676 ? 31.079 79.844 -38.006 1.00 19.18 ? 676 ILE A CG1 1 ATOM 5497 C CG2 . ILE A 1 676 ? 30.716 81.582 -39.795 1.00 27.90 ? 676 ILE A CG2 1 ATOM 5498 C CD1 . ILE A 1 676 ? 32.502 79.359 -37.805 1.00 27.76 ? 676 ILE A CD1 1 ATOM 5499 N N A SER A 1 677 ? 31.049 77.306 -40.676 0.50 14.06 ? 677 SER A N 1 ATOM 5500 N N B SER A 1 677 ? 31.049 77.306 -40.676 0.50 14.06 ? 677 SER A N 1 ATOM 5501 C CA A SER A 1 677 ? 31.550 75.943 -40.714 0.50 17.75 ? 677 SER A CA 1 ATOM 5502 C CA B SER A 1 677 ? 31.550 75.943 -40.714 0.50 17.64 ? 677 SER A CA 1 ATOM 5503 C C A SER A 1 677 ? 33.061 75.978 -40.818 0.50 17.77 ? 677 SER A C 1 ATOM 5504 C C B SER A 1 677 ? 33.061 75.978 -40.818 0.50 17.75 ? 677 SER A C 1 ATOM 5505 O O A SER A 1 677 ? 33.639 76.820 -41.505 0.50 18.69 ? 677 SER A O 1 ATOM 5506 O O B SER A 1 677 ? 33.639 76.820 -41.505 0.50 18.70 ? 677 SER A O 1 ATOM 5507 C CB A SER A 1 677 ? 30.938 75.238 -41.954 0.50 19.96 ? 677 SER A CB 1 ATOM 5508 C CB B SER A 1 677 ? 30.938 75.238 -41.954 0.50 19.67 ? 677 SER A CB 1 ATOM 5509 O OG A SER A 1 677 ? 31.465 73.956 -42.147 0.50 23.51 ? 677 SER A OG 1 ATOM 5510 O OG B SER A 1 677 ? 29.641 74.772 -41.711 0.50 23.81 ? 677 SER A OG 1 ATOM 5511 N N . LEU A 1 678 ? 33.744 75.036 -40.156 1.00 14.99 ? 678 LEU A N 1 ATOM 5512 C CA . LEU A 1 678 ? 35.191 74.981 -40.173 1.00 15.53 ? 678 LEU A CA 1 ATOM 5513 C C . LEU A 1 678 ? 35.619 73.523 -40.267 1.00 14.77 ? 678 LEU A C 1 ATOM 5514 O O . LEU A 1 678 ? 34.873 72.634 -39.747 1.00 15.78 ? 678 LEU A O 1 ATOM 5515 C CB . LEU A 1 678 ? 35.772 75.536 -38.861 1.00 17.13 ? 678 LEU A CB 1 ATOM 5516 C CG . LEU A 1 678 ? 35.731 77.032 -38.659 1.00 16.82 ? 678 LEU A CG 1 ATOM 5517 C CD1 . LEU A 1 678 ? 36.056 77.294 -37.197 1.00 19.18 ? 678 LEU A CD1 1 ATOM 5518 C CD2 . LEU A 1 678 ? 36.790 77.702 -39.517 1.00 24.71 ? 678 LEU A CD2 1 ATOM 5519 N N . ARG A 1 679 ? 36.779 73.321 -40.851 1.00 14.00 ? 679 ARG A N 1 ATOM 5520 C CA . ARG A 1 679 ? 37.397 72.011 -40.947 1.00 15.55 ? 679 ARG A CA 1 ATOM 5521 C C . ARG A 1 679 ? 38.913 72.189 -40.886 1.00 17.85 ? 679 ARG A C 1 ATOM 5522 O O . ARG A 1 679 ? 39.489 72.961 -41.681 1.00 19.10 ? 679 ARG A O 1 ATOM 5523 C CB . ARG A 1 679 ? 37.023 71.330 -42.270 1.00 19.46 ? 679 ARG A CB 1 ATOM 5524 C CG . ARG A 1 679 ? 37.506 69.868 -42.315 1.00 21.07 ? 679 ARG A CG 1 ATOM 5525 C CD . ARG A 1 679 ? 37.321 69.249 -43.706 1.00 25.46 ? 679 ARG A CD 1 ATOM 5526 N NE . ARG A 1 679 ? 37.618 67.831 -43.574 1.00 31.16 ? 679 ARG A NE 1 ATOM 5527 C CZ . ARG A 1 679 ? 37.696 66.957 -44.569 1.00 36.05 ? 679 ARG A CZ 1 ATOM 5528 N NH1 . ARG A 1 679 ? 37.492 67.334 -45.832 1.00 38.55 ? 679 ARG A NH1 1 ATOM 5529 N NH2 . ARG A 1 679 ? 37.991 65.697 -44.277 1.00 37.18 ? 679 ARG A NH2 1 ATOM 5530 N N . VAL A 1 680 ? 39.596 71.501 -39.958 1.00 14.97 ? 680 VAL A N 1 ATOM 5531 C CA . VAL A 1 680 ? 41.044 71.521 -39.892 1.00 15.14 ? 680 VAL A CA 1 ATOM 5532 C C . VAL A 1 680 ? 41.579 70.169 -40.359 1.00 18.30 ? 680 VAL A C 1 ATOM 5533 O O . VAL A 1 680 ? 41.035 69.129 -39.968 1.00 17.09 ? 680 VAL A O 1 ATOM 5534 C CB . VAL A 1 680 ? 41.564 71.789 -38.461 1.00 14.49 ? 680 VAL A CB 1 ATOM 5535 C CG1 . VAL A 1 680 ? 43.058 71.608 -38.386 1.00 16.79 ? 680 VAL A CG1 1 ATOM 5536 C CG2 . VAL A 1 680 ? 41.112 73.228 -38.047 1.00 13.74 ? 680 VAL A CG2 1 ATOM 5537 N N . GLY A 1 681 ? 42.602 70.202 -41.219 1.00 18.38 ? 681 GLY A N 1 ATOM 5538 C CA . GLY A 1 681 ? 43.160 68.947 -41.752 1.00 24.22 ? 681 GLY A CA 1 ATOM 5539 C C . GLY A 1 681 ? 42.089 68.080 -42.441 1.00 24.00 ? 681 GLY A C 1 ATOM 5540 O O . GLY A 1 681 ? 41.216 68.583 -43.169 1.00 25.23 ? 681 GLY A O 1 ATOM 5541 N N . ASN A 1 682 ? 42.150 66.771 -42.174 1.00 30.36 ? 682 ASN A N 1 ATOM 5542 C CA . ASN A 1 682 ? 41.171 65.839 -42.755 1.00 32.11 ? 682 ASN A CA 1 ATOM 5543 C C . ASN A 1 682 ? 40.192 65.495 -41.680 1.00 33.90 ? 682 ASN A C 1 ATOM 5544 O O . ASN A 1 682 ? 39.442 64.529 -41.801 1.00 37.42 ? 682 ASN A O 1 ATOM 5545 C CB . ASN A 1 682 ? 41.827 64.537 -43.196 1.00 35.75 ? 682 ASN A CB 1 ATOM 5546 C CG . ASN A 1 682 ? 42.898 64.756 -44.202 1.00 39.09 ? 682 ASN A CG 1 ATOM 5547 O OD1 . ASN A 1 682 ? 42.680 65.415 -45.229 1.00 45.54 ? 682 ASN A OD1 1 ATOM 5548 N ND2 . ASN A 1 682 ? 44.079 64.213 -43.928 1.00 43.79 ? 682 ASN A ND2 1 ATOM 5549 N N . GLY A 1 683 ? 40.188 66.298 -40.628 1.00 30.83 ? 683 GLY A N 1 ATOM 5550 C CA . GLY A 1 683 ? 39.342 66.000 -39.496 1.00 28.04 ? 683 GLY A CA 1 ATOM 5551 C C . GLY A 1 683 ? 37.885 66.275 -39.730 1.00 23.81 ? 683 GLY A C 1 ATOM 5552 O O . GLY A 1 683 ? 37.464 66.495 -40.868 1.00 23.76 ? 683 GLY A O 1 ATOM 5553 N N . PRO A 1 684 ? 37.097 66.322 -38.663 1.00 18.52 ? 684 PRO A N 1 ATOM 5554 C CA . PRO A 1 684 ? 35.659 66.578 -38.827 1.00 18.09 ? 684 PRO A CA 1 ATOM 5555 C C . PRO A 1 684 ? 35.338 68.018 -39.258 1.00 15.62 ? 684 PRO A C 1 ATOM 5556 O O . PRO A 1 684 ? 36.154 68.899 -39.097 1.00 15.71 ? 684 PRO A O 1 ATOM 5557 C CB . PRO A 1 684 ? 35.105 66.267 -37.437 1.00 18.74 ? 684 PRO A CB 1 ATOM 5558 C CG . PRO A 1 684 ? 36.268 66.703 -36.509 1.00 20.83 ? 684 PRO A CG 1 ATOM 5559 C CD . PRO A 1 684 ? 37.454 66.125 -37.238 1.00 20.32 ? 684 PRO A CD 1 ATOM 5560 N N . THR A 1 685 ? 34.152 68.211 -39.818 1.00 15.79 ? 685 THR A N 1 ATOM 5561 C CA . THR A 1 685 ? 33.694 69.563 -40.206 1.00 15.79 ? 685 THR A CA 1 ATOM 5562 C C . THR A 1 685 ? 32.672 69.908 -39.157 1.00 15.30 ? 685 THR A C 1 ATOM 5563 O O . THR A 1 685 ? 31.741 69.161 -38.942 1.00 16.53 ? 685 THR A O 1 ATOM 5564 C CB . THR A 1 685 ? 33.059 69.573 -41.609 1.00 16.90 ? 685 THR A CB 1 ATOM 5565 O OG1 . THR A 1 685 ? 34.074 69.250 -42.541 1.00 19.75 ? 685 THR A OG1 1 ATOM 5566 C CG2 . THR A 1 685 ? 32.459 70.961 -41.923 1.00 19.36 ? 685 THR A CG2 1 ATOM 5567 N N . LEU A 1 686 ? 32.839 71.052 -38.486 1.00 12.09 ? 686 LEU A N 1 ATOM 5568 C CA . LEU A 1 686 ? 31.943 71.466 -37.434 1.00 13.79 ? 686 LEU A CA 1 ATOM 5569 C C . LEU A 1 686 ? 31.114 72.686 -37.884 1.00 11.51 ? 686 LEU A C 1 ATOM 5570 O O . LEU A 1 686 ? 31.736 73.640 -38.496 1.00 13.44 ? 686 LEU A O 1 ATOM 5571 C CB . LEU A 1 686 ? 32.746 71.870 -36.182 1.00 11.96 ? 686 LEU A CB 1 ATOM 5572 C CG . LEU A 1 686 ? 33.682 70.819 -35.558 1.00 18.63 ? 686 LEU A CG 1 ATOM 5573 C CD1 . LEU A 1 686 ? 33.945 71.212 -34.090 1.00 16.99 ? 686 LEU A CD1 1 ATOM 5574 C CD2 . LEU A 1 686 ? 33.210 69.439 -35.649 1.00 18.43 ? 686 LEU A CD2 1 ATOM 5575 N N . ALA A 1 687 ? 29.825 72.703 -37.618 1.00 12.47 ? 687 ALA A N 1 ATOM 5576 C CA . ALA A 1 687 ? 29.013 73.859 -37.982 1.00 13.59 ? 687 ALA A CA 1 ATOM 5577 C C . ALA A 1 687 ? 28.576 74.532 -36.692 1.00 14.77 ? 687 ALA A C 1 ATOM 5578 O O . ALA A 1 687 ? 28.277 73.836 -35.688 1.00 13.86 ? 687 ALA A O 1 ATOM 5579 C CB . ALA A 1 687 ? 27.758 73.370 -38.799 1.00 12.98 ? 687 ALA A CB 1 ATOM 5580 N N . PHE A 1 688 ? 28.497 75.874 -36.688 1.00 13.08 ? 688 PHE A N 1 ATOM 5581 C CA . PHE A 1 688 ? 28.139 76.639 -35.545 1.00 11.19 ? 688 PHE A CA 1 ATOM 5582 C C . PHE A 1 688 ? 26.961 77.545 -35.806 1.00 12.03 ? 688 PHE A C 1 ATOM 5583 O O . PHE A 1 688 ? 26.831 78.050 -36.954 1.00 14.85 ? 688 PHE A O 1 ATOM 5584 C CB . PHE A 1 688 ? 29.322 77.521 -35.089 1.00 13.14 ? 688 PHE A CB 1 ATOM 5585 C CG . PHE A 1 688 ? 30.565 76.720 -34.753 1.00 10.80 ? 688 PHE A CG 1 ATOM 5586 C CD1 . PHE A 1 688 ? 31.401 76.246 -35.732 1.00 11.70 ? 688 PHE A CD1 1 ATOM 5587 C CD2 . PHE A 1 688 ? 30.847 76.422 -33.419 1.00 10.97 ? 688 PHE A CD2 1 ATOM 5588 C CE1 . PHE A 1 688 ? 32.526 75.474 -35.430 1.00 11.25 ? 688 PHE A CE1 1 ATOM 5589 C CE2 . PHE A 1 688 ? 31.966 75.658 -33.126 1.00 10.98 ? 688 PHE A CE2 1 ATOM 5590 C CZ . PHE A 1 688 ? 32.799 75.190 -34.079 1.00 11.37 ? 688 PHE A CZ 1 ATOM 5591 N N . SER A 1 689 ? 26.166 77.817 -34.816 1.00 12.77 ? 689 SER A N 1 ATOM 5592 C CA . SER A 1 689 ? 25.039 78.748 -34.924 1.00 13.55 ? 689 SER A CA 1 ATOM 5593 C C . SER A 1 689 ? 25.613 80.185 -34.954 1.00 14.90 ? 689 SER A C 1 ATOM 5594 O O . SER A 1 689 ? 26.804 80.438 -34.704 1.00 13.82 ? 689 SER A O 1 ATOM 5595 C CB . SER A 1 689 ? 24.137 78.623 -33.705 1.00 14.20 ? 689 SER A CB 1 ATOM 5596 O OG . SER A 1 689 ? 24.767 79.176 -32.556 1.00 16.15 ? 689 SER A OG 1 ATOM 5597 N N . GLU A 1 690 ? 24.733 81.141 -35.239 1.00 14.16 ? 690 GLU A N 1 ATOM 5598 C CA . GLU A 1 690 ? 25.165 82.538 -35.229 1.00 13.36 ? 690 GLU A CA 1 ATOM 5599 C C . GLU A 1 690 ? 25.540 83.001 -33.829 1.00 16.06 ? 690 GLU A C 1 ATOM 5600 O O . GLU A 1 690 ? 26.101 84.090 -33.652 1.00 14.02 ? 690 GLU A O 1 ATOM 5601 C CB . GLU A 1 690 ? 24.079 83.435 -35.835 1.00 18.25 ? 690 GLU A CB 1 ATOM 5602 C CG . GLU A 1 690 ? 22.945 83.753 -34.967 1.00 21.13 ? 690 GLU A CG 1 ATOM 5603 C CD . GLU A 1 690 ? 22.115 84.865 -35.621 1.00 29.19 ? 690 GLU A CD 1 ATOM 5604 O OE1 . GLU A 1 690 ? 21.576 84.568 -36.704 1.00 31.89 ? 690 GLU A OE1 1 ATOM 5605 O OE2 . GLU A 1 690 ? 22.019 86.013 -35.081 1.00 33.76 ? 690 GLU A OE2 1 ATOM 5606 N N . GLN A 1 691 ? 25.214 82.190 -32.812 1.00 15.40 ? 691 GLN A N 1 ATOM 5607 C CA . GLN A 1 691 ? 25.627 82.523 -31.437 1.00 14.94 ? 691 GLN A CA 1 ATOM 5608 C C . GLN A 1 691 ? 26.978 81.867 -31.080 1.00 10.97 ? 691 GLN A C 1 ATOM 5609 O O . GLN A 1 691 ? 27.397 81.962 -29.905 1.00 16.40 ? 691 GLN A O 1 ATOM 5610 C CB . GLN A 1 691 ? 24.586 82.144 -30.375 1.00 17.31 ? 691 GLN A CB 1 ATOM 5611 C CG . GLN A 1 691 ? 23.331 82.965 -30.466 1.00 23.33 ? 691 GLN A CG 1 ATOM 5612 C CD . GLN A 1 691 ? 22.230 82.045 -30.545 1.00 34.15 ? 691 GLN A CD 1 ATOM 5613 O OE1 . GLN A 1 691 ? 21.747 81.543 -29.519 1.00 31.18 ? 691 GLN A OE1 1 ATOM 5614 N NE2 . GLN A 1 691 ? 21.834 81.725 -31.774 1.00 34.85 ? 691 GLN A NE2 1 ATOM 5615 N N . GLY A 1 692 ? 27.656 81.266 -32.028 1.00 11.43 ? 692 GLY A N 1 ATOM 5616 C CA . GLY A 1 692 ? 28.984 80.701 -31.759 1.00 12.73 ? 692 GLY A CA 1 ATOM 5617 C C . GLY A 1 692 ? 28.967 79.350 -31.082 1.00 12.21 ? 692 GLY A C 1 ATOM 5618 O O . GLY A 1 692 ? 30.009 78.931 -30.585 1.00 13.99 ? 692 GLY A O 1 ATOM 5619 N N . LEU A 1 693 ? 27.823 78.661 -31.099 1.00 12.36 ? 693 LEU A N 1 ATOM 5620 C CA . LEU A 1 693 ? 27.676 77.336 -30.432 1.00 12.11 ? 693 LEU A CA 1 ATOM 5621 C C . LEU A 1 693 ? 27.583 76.250 -31.414 1.00 12.30 ? 693 LEU A C 1 ATOM 5622 O O . LEU A 1 693 ? 26.868 76.375 -32.454 1.00 12.89 ? 693 LEU A O 1 ATOM 5623 C CB . LEU A 1 693 ? 26.437 77.346 -29.537 1.00 13.90 ? 693 LEU A CB 1 ATOM 5624 C CG . LEU A 1 693 ? 26.562 78.324 -28.368 1.00 16.40 ? 693 LEU A CG 1 ATOM 5625 C CD1 . LEU A 1 693 ? 25.136 78.662 -27.940 1.00 20.87 ? 693 LEU A CD1 1 ATOM 5626 C CD2 . LEU A 1 693 ? 27.382 77.741 -27.232 1.00 19.30 ? 693 LEU A CD2 1 ATOM 5627 N N . LEU A 1 694 ? 28.253 75.125 -31.151 1.00 11.96 ? 694 LEU A N 1 ATOM 5628 C CA . LEU A 1 694 ? 28.205 73.992 -32.048 1.00 11.46 ? 694 LEU A CA 1 ATOM 5629 C C . LEU A 1 694 ? 26.756 73.593 -32.333 1.00 11.08 ? 694 LEU A C 1 ATOM 5630 O O . LEU A 1 694 ? 25.896 73.598 -31.441 1.00 12.05 ? 694 LEU A O 1 ATOM 5631 C CB . LEU A 1 694 ? 28.935 72.792 -31.365 1.00 12.59 ? 694 LEU A CB 1 ATOM 5632 C CG . LEU A 1 694 ? 29.108 71.557 -32.231 1.00 12.55 ? 694 LEU A CG 1 ATOM 5633 C CD1 . LEU A 1 694 ? 30.032 71.810 -33.344 1.00 13.45 ? 694 LEU A CD1 1 ATOM 5634 C CD2 . LEU A 1 694 ? 29.607 70.371 -31.356 1.00 14.08 ? 694 LEU A CD2 1 ATOM 5635 N N . LYS A 1 695 ? 26.510 73.237 -33.603 1.00 11.95 ? 695 LYS A N 1 ATOM 5636 C CA . LYS A 1 695 ? 25.186 72.726 -33.982 1.00 13.16 ? 695 LYS A CA 1 ATOM 5637 C C . LYS A 1 695 ? 25.323 71.392 -34.692 1.00 12.19 ? 695 LYS A C 1 ATOM 5638 O O . LYS A 1 695 ? 24.337 70.618 -34.640 1.00 14.85 ? 695 LYS A O 1 ATOM 5639 C CB . LYS A 1 695 ? 24.354 73.727 -34.845 1.00 17.36 ? 695 LYS A CB 1 ATOM 5640 C CG . LYS A 1 695 ? 24.958 74.167 -36.130 1.00 19.91 ? 695 LYS A CG 1 ATOM 5641 C CD . LYS A 1 695 ? 23.972 75.166 -36.831 1.00 24.04 ? 695 LYS A CD 1 ATOM 5642 C CE . LYS A 1 695 ? 23.003 74.431 -37.756 1.00 33.30 ? 695 LYS A CE 1 ATOM 5643 N NZ . LYS A 1 695 ? 21.978 75.373 -38.384 1.00 34.80 ? 695 LYS A NZ 1 ATOM 5644 N N . SER A 1 696 ? 26.435 71.053 -35.308 1.00 12.60 ? 696 SER A N 1 ATOM 5645 C CA . SER A 1 696 ? 26.571 69.742 -35.957 1.00 13.81 ? 696 SER A CA 1 ATOM 5646 C C . SER A 1 696 ? 28.019 69.358 -36.159 1.00 13.78 ? 696 SER A C 1 ATOM 5647 O O . SER A 1 696 ? 28.919 70.230 -36.224 1.00 13.52 ? 696 SER A O 1 ATOM 5648 C CB . SER A 1 696 ? 25.770 69.708 -37.309 1.00 15.45 ? 696 SER A CB 1 ATOM 5649 O OG . SER A 1 696 ? 26.400 70.472 -38.330 1.00 17.61 ? 696 SER A OG 1 ATOM 5650 N N . ILE A 1 697 ? 28.290 68.046 -36.346 1.00 13.84 ? 697 ILE A N 1 ATOM 5651 C CA . ILE A 1 697 ? 29.575 67.469 -36.600 1.00 13.27 ? 697 ILE A CA 1 ATOM 5652 C C . ILE A 1 697 ? 29.447 66.526 -37.791 1.00 15.98 ? 697 ILE A C 1 ATOM 5653 O O . ILE A 1 697 ? 28.582 65.624 -37.770 1.00 17.29 ? 697 ILE A O 1 ATOM 5654 C CB . ILE A 1 697 ? 30.119 66.634 -35.382 1.00 14.21 ? 697 ILE A CB 1 ATOM 5655 C CG1 . ILE A 1 697 ? 30.253 67.574 -34.172 1.00 13.24 ? 697 ILE A CG1 1 ATOM 5656 C CG2 . ILE A 1 697 ? 31.477 66.038 -35.697 1.00 14.47 ? 697 ILE A CG2 1 ATOM 5657 C CD1 . ILE A 1 697 ? 30.759 66.811 -32.880 1.00 13.00 ? 697 ILE A CD1 1 ATOM 5658 N N . GLN A 1 698 ? 30.307 66.687 -38.775 1.00 14.93 ? 698 GLN A N 1 ATOM 5659 C CA . GLN A 1 698 ? 30.291 65.807 -39.937 1.00 16.41 ? 698 GLN A CA 1 ATOM 5660 C C . GLN A 1 698 ? 31.613 65.105 -39.889 1.00 15.40 ? 698 GLN A C 1 ATOM 5661 O O . GLN A 1 698 ? 32.666 65.708 -40.037 1.00 16.31 ? 698 GLN A O 1 ATOM 5662 C CB . GLN A 1 698 ? 30.162 66.654 -41.224 1.00 17.72 ? 698 GLN A CB 1 ATOM 5663 C CG . GLN A 1 698 ? 30.320 65.685 -42.435 1.00 22.92 ? 698 GLN A CG 1 ATOM 5664 C CD . GLN A 1 698 ? 30.309 66.411 -43.744 1.00 24.05 ? 698 GLN A CD 1 ATOM 5665 O OE1 . GLN A 1 698 ? 29.413 66.182 -44.589 1.00 29.61 ? 698 GLN A OE1 1 ATOM 5666 N NE2 . GLN A 1 698 ? 31.272 67.288 -43.933 1.00 24.69 ? 698 GLN A NE2 1 ATOM 5667 N N . LEU A 1 699 ? 31.604 63.784 -39.692 1.00 17.27 ? 699 LEU A N 1 ATOM 5668 C CA . LEU A 1 699 ? 32.882 63.108 -39.529 1.00 20.18 ? 699 LEU A CA 1 ATOM 5669 C C . LEU A 1 699 ? 33.838 63.036 -40.733 1.00 24.98 ? 699 LEU A C 1 ATOM 5670 O O . LEU A 1 699 ? 35.034 63.234 -40.576 1.00 25.94 ? 699 LEU A O 1 ATOM 5671 C CB . LEU A 1 699 ? 32.649 61.690 -38.924 1.00 23.46 ? 699 LEU A CB 1 ATOM 5672 C CG . LEU A 1 699 ? 32.028 61.647 -37.513 1.00 20.78 ? 699 LEU A CG 1 ATOM 5673 C CD1 . LEU A 1 699 ? 31.888 60.201 -37.072 1.00 23.31 ? 699 LEU A CD1 1 ATOM 5674 C CD2 . LEU A 1 699 ? 32.924 62.428 -36.532 1.00 18.91 ? 699 LEU A CD2 1 ATOM 5675 N N . THR A 1 700 ? 33.292 62.821 -41.927 1.00 28.09 ? 700 THR A N 1 ATOM 5676 C CA . THR A 1 700 ? 34.121 62.736 -43.129 1.00 32.96 ? 700 THR A CA 1 ATOM 5677 C C . THR A 1 700 ? 33.417 63.498 -44.251 1.00 32.72 ? 700 THR A C 1 ATOM 5678 O O . THR A 1 700 ? 32.272 63.896 -44.095 1.00 31.98 ? 700 THR A O 1 ATOM 5679 C CB . THR A 1 700 ? 34.336 61.253 -43.554 1.00 32.92 ? 700 THR A CB 1 ATOM 5680 O OG1 . THR A 1 700 ? 33.060 60.627 -43.732 1.00 35.02 ? 700 THR A OG1 1 ATOM 5681 C CG2 . THR A 1 700 ? 35.139 60.495 -42.488 1.00 34.87 ? 700 THR A CG2 1 ATOM 5682 N N . GLN A 1 701 ? 34.122 63.726 -45.363 1.00 37.70 ? 701 GLN A N 1 ATOM 5683 C CA . GLN A 1 701 ? 33.564 64.451 -46.517 1.00 40.51 ? 701 GLN A CA 1 ATOM 5684 C C . GLN A 1 701 ? 32.198 63.919 -46.929 1.00 41.46 ? 701 GLN A C 1 ATOM 5685 O O . GLN A 1 701 ? 31.245 64.682 -47.128 1.00 43.20 ? 701 GLN A O 1 ATOM 5686 C CB . GLN A 1 701 ? 34.499 64.339 -47.734 1.00 42.70 ? 701 GLN A CB 1 ATOM 5687 C CG . GLN A 1 701 ? 35.672 65.301 -47.770 1.00 44.54 ? 701 GLN A CG 1 ATOM 5688 C CD . GLN A 1 701 ? 35.247 66.749 -48.029 1.00 46.69 ? 701 GLN A CD 1 ATOM 5689 O OE1 . GLN A 1 701 ? 36.068 67.599 -48.423 1.00 45.44 ? 701 GLN A OE1 1 ATOM 5690 N NE2 . GLN A 1 701 ? 33.957 67.043 -47.794 1.00 47.37 ? 701 GLN A NE2 1 ATOM 5691 N N . ASP A 1 702 ? 32.117 62.600 -47.039 1.00 42.32 ? 702 ASP A N 1 ATOM 5692 C CA . ASP A 1 702 ? 30.907 61.911 -47.458 1.00 44.78 ? 702 ASP A CA 1 ATOM 5693 C C . ASP A 1 702 ? 29.794 61.811 -46.417 1.00 44.36 ? 702 ASP A C 1 ATOM 5694 O O . ASP A 1 702 ? 28.595 61.978 -46.737 1.00 43.79 ? 702 ASP A O 1 ATOM 5695 C CB . ASP A 1 702 ? 31.285 60.500 -47.947 1.00 47.39 ? 702 ASP A CB 1 ATOM 5696 C CG . ASP A 1 702 ? 32.291 60.526 -49.113 1.00 51.25 ? 702 ASP A CG 1 ATOM 5697 O OD1 . ASP A 1 702 ? 32.859 59.444 -49.436 1.00 53.70 ? 702 ASP A OD1 1 ATOM 5698 O OD2 . ASP A 1 702 ? 32.508 61.621 -49.711 1.00 51.02 ? 702 ASP A OD2 1 ATOM 5699 N N . SER A 1 703 ? 30.188 61.580 -45.164 1.00 41.29 ? 703 SER A N 1 ATOM 5700 C CA . SER A 1 703 ? 29.227 61.403 -44.084 1.00 36.67 ? 703 SER A CA 1 ATOM 5701 C C . SER A 1 703 ? 28.276 62.568 -43.828 1.00 33.76 ? 703 SER A C 1 ATOM 5702 O O . SER A 1 703 ? 28.490 63.679 -44.319 1.00 35.23 ? 703 SER A O 1 ATOM 5703 C CB . SER A 1 703 ? 29.976 61.049 -42.796 1.00 37.59 ? 703 SER A CB 1 ATOM 5704 O OG . SER A 1 703 ? 30.674 62.173 -42.271 1.00 33.47 ? 703 SER A OG 1 ATOM 5705 N N . PRO A 1 704 ? 27.191 62.316 -43.067 1.00 33.48 ? 704 PRO A N 1 ATOM 5706 C CA . PRO A 1 704 ? 26.140 63.256 -42.671 1.00 30.96 ? 704 PRO A CA 1 ATOM 5707 C C . PRO A 1 704 ? 26.467 64.300 -41.564 1.00 30.01 ? 704 PRO A C 1 ATOM 5708 O O . PRO A 1 704 ? 27.345 64.084 -40.716 1.00 28.39 ? 704 PRO A O 1 ATOM 5709 C CB . PRO A 1 704 ? 24.979 62.353 -42.267 1.00 35.34 ? 704 PRO A CB 1 ATOM 5710 C CG . PRO A 1 704 ? 25.581 61.080 -41.936 1.00 31.73 ? 704 PRO A CG 1 ATOM 5711 C CD . PRO A 1 704 ? 26.844 60.925 -42.705 1.00 34.01 ? 704 PRO A CD 1 ATOM 5712 N N . HIS A 1 705 ? 25.776 65.442 -41.609 1.00 26.58 ? 705 HIS A N 1 ATOM 5713 C CA . HIS A 1 705 ? 26.005 66.468 -40.568 1.00 24.71 ? 705 HIS A CA 1 ATOM 5714 C C . HIS A 1 705 ? 25.154 66.066 -39.356 1.00 23.88 ? 705 HIS A C 1 ATOM 5715 O O . HIS A 1 705 ? 23.986 66.374 -39.264 1.00 23.63 ? 705 HIS A O 1 ATOM 5716 C CB . HIS A 1 705 ? 25.596 67.866 -41.088 1.00 28.14 ? 705 HIS A CB 1 ATOM 5717 C CG . HIS A 1 705 ? 26.456 68.352 -42.210 1.00 31.24 ? 705 HIS A CG 1 ATOM 5718 N ND1 . HIS A 1 705 ? 27.636 69.032 -42.001 1.00 29.58 ? 705 HIS A ND1 1 ATOM 5719 C CD2 . HIS A 1 705 ? 26.395 68.116 -43.545 1.00 33.08 ? 705 HIS A CD2 1 ATOM 5720 C CE1 . HIS A 1 705 ? 28.277 69.178 -43.148 1.00 34.17 ? 705 HIS A CE1 1 ATOM 5721 N NE2 . HIS A 1 705 ? 27.544 68.630 -44.105 1.00 35.30 ? 705 HIS A NE2 1 ATOM 5722 N N . VAL A 1 706 ? 25.776 65.401 -38.373 1.00 19.73 ? 706 VAL A N 1 ATOM 5723 C CA . VAL A 1 706 ? 25.039 64.953 -37.194 1.00 18.34 ? 706 VAL A CA 1 ATOM 5724 C C . VAL A 1 706 ? 24.681 66.054 -36.210 1.00 17.46 ? 706 VAL A C 1 ATOM 5725 O O . VAL A 1 706 ? 25.587 66.760 -35.776 1.00 16.50 ? 706 VAL A O 1 ATOM 5726 C CB . VAL A 1 706 ? 25.901 63.872 -36.437 1.00 18.12 ? 706 VAL A CB 1 ATOM 5727 C CG1 . VAL A 1 706 ? 25.130 63.392 -35.231 1.00 16.62 ? 706 VAL A CG1 1 ATOM 5728 C CG2 . VAL A 1 706 ? 26.308 62.745 -37.414 1.00 18.13 ? 706 VAL A CG2 1 ATOM 5729 N N . PRO A 1 707 ? 23.421 66.239 -35.819 1.00 16.25 ? 707 PRO A N 1 ATOM 5730 C CA . PRO A 1 707 ? 23.075 67.291 -34.869 1.00 18.94 ? 707 PRO A CA 1 ATOM 5731 C C . PRO A 1 707 ? 23.727 67.038 -33.512 1.00 17.97 ? 707 PRO A C 1 ATOM 5732 O O . PRO A 1 707 ? 23.577 65.970 -32.903 1.00 17.84 ? 707 PRO A O 1 ATOM 5733 C CB . PRO A 1 707 ? 21.560 67.215 -34.762 1.00 19.16 ? 707 PRO A CB 1 ATOM 5734 C CG . PRO A 1 707 ? 21.132 66.613 -36.111 1.00 22.66 ? 707 PRO A CG 1 ATOM 5735 C CD . PRO A 1 707 ? 22.188 65.571 -36.345 1.00 17.42 ? 707 PRO A CD 1 ATOM 5736 N N . VAL A 1 708 ? 24.480 68.045 -33.055 1.00 16.29 ? 708 VAL A N 1 ATOM 5737 C CA . VAL A 1 708 ? 25.158 67.999 -31.738 1.00 14.16 ? 708 VAL A CA 1 ATOM 5738 C C . VAL A 1 708 ? 25.127 69.484 -31.327 1.00 12.56 ? 708 VAL A C 1 ATOM 5739 O O . VAL A 1 708 ? 25.887 70.318 -31.937 1.00 13.35 ? 708 VAL A O 1 ATOM 5740 C CB . VAL A 1 708 ? 26.597 67.469 -31.878 1.00 13.61 ? 708 VAL A CB 1 ATOM 5741 C CG1 . VAL A 1 708 ? 27.309 67.514 -30.445 1.00 14.28 ? 708 VAL A CG1 1 ATOM 5742 C CG2 . VAL A 1 708 ? 26.607 66.012 -32.430 1.00 18.52 ? 708 VAL A CG2 1 ATOM 5743 N N A HIS A 1 709 ? 24.280 69.842 -30.407 0.50 12.28 ? 709 HIS A N 1 ATOM 5744 N N B HIS A 1 709 ? 24.280 69.842 -30.407 0.50 12.92 ? 709 HIS A N 1 ATOM 5745 C CA A HIS A 1 709 ? 24.137 71.249 -30.060 0.50 13.38 ? 709 HIS A CA 1 ATOM 5746 C CA B HIS A 1 709 ? 24.137 71.249 -30.060 0.50 14.38 ? 709 HIS A CA 1 ATOM 5747 C C A HIS A 1 709 ? 24.546 71.562 -28.629 0.50 13.78 ? 709 HIS A C 1 ATOM 5748 C C B HIS A 1 709 ? 24.546 71.562 -28.629 0.50 14.39 ? 709 HIS A C 1 ATOM 5749 O O A HIS A 1 709 ? 24.070 70.912 -27.684 0.50 14.39 ? 709 HIS A O 1 ATOM 5750 O O B HIS A 1 709 ? 24.077 70.906 -27.685 0.50 14.85 ? 709 HIS A O 1 ATOM 5751 C CB A HIS A 1 709 ? 22.671 71.655 -30.218 0.50 16.17 ? 709 HIS A CB 1 ATOM 5752 C CB B HIS A 1 709 ? 22.671 71.655 -30.218 0.50 17.70 ? 709 HIS A CB 1 ATOM 5753 C CG A HIS A 1 709 ? 22.147 71.593 -31.620 0.50 19.54 ? 709 HIS A CG 1 ATOM 5754 C CG B HIS A 1 709 ? 22.414 73.129 -30.152 0.50 22.93 ? 709 HIS A CG 1 ATOM 5755 N ND1 A HIS A 1 709 ? 21.709 72.710 -32.299 0.50 23.06 ? 709 HIS A ND1 1 ATOM 5756 N ND1 B HIS A 1 709 ? 21.344 73.667 -29.470 0.50 25.56 ? 709 HIS A ND1 1 ATOM 5757 C CD2 A HIS A 1 709 ? 22.029 70.555 -32.484 0.50 22.14 ? 709 HIS A CD2 1 ATOM 5758 C CD2 B HIS A 1 709 ? 23.112 74.180 -30.650 0.50 24.71 ? 709 HIS A CD2 1 ATOM 5759 C CE1 A HIS A 1 709 ? 21.349 72.365 -33.525 0.50 24.06 ? 709 HIS A CE1 1 ATOM 5760 C CE1 B HIS A 1 709 ? 21.395 74.988 -29.544 0.50 27.53 ? 709 HIS A CE1 1 ATOM 5761 N NE2 A HIS A 1 709 ? 21.543 71.062 -33.663 0.50 14.01 ? 709 HIS A NE2 1 ATOM 5762 N NE2 B HIS A 1 709 ? 22.466 75.322 -30.248 0.50 27.26 ? 709 HIS A NE2 1 ATOM 5763 N N . PHE A 1 710 ? 25.431 72.531 -28.456 1.00 12.17 ? 710 PHE A N 1 ATOM 5764 C CA . PHE A 1 710 ? 25.783 72.995 -27.131 1.00 11.62 ? 710 PHE A CA 1 ATOM 5765 C C . PHE A 1 710 ? 24.783 74.077 -26.692 1.00 13.53 ? 710 PHE A C 1 ATOM 5766 O O . PHE A 1 710 ? 24.388 74.960 -27.535 1.00 13.38 ? 710 PHE A O 1 ATOM 5767 C CB . PHE A 1 710 ? 27.194 73.616 -27.071 1.00 12.80 ? 710 PHE A CB 1 ATOM 5768 C CG . PHE A 1 710 ? 28.303 72.648 -26.666 1.00 12.90 ? 710 PHE A CG 1 ATOM 5769 C CD1 . PHE A 1 710 ? 29.408 72.463 -27.484 1.00 14.16 ? 710 PHE A CD1 1 ATOM 5770 C CD2 . PHE A 1 710 ? 28.250 71.945 -25.457 1.00 14.15 ? 710 PHE A CD2 1 ATOM 5771 C CE1 . PHE A 1 710 ? 30.470 71.562 -27.066 1.00 14.00 ? 710 PHE A CE1 1 ATOM 5772 C CE2 . PHE A 1 710 ? 29.263 71.070 -25.061 1.00 14.66 ? 710 PHE A CE2 1 ATOM 5773 C CZ . PHE A 1 710 ? 30.348 70.892 -25.850 1.00 14.03 ? 710 PHE A CZ 1 ATOM 5774 N N . LYS A 1 711 ? 24.376 74.067 -25.444 1.00 10.92 ? 711 LYS A N 1 ATOM 5775 C CA . LYS A 1 711 ? 23.467 75.023 -24.868 1.00 13.77 ? 711 LYS A CA 1 ATOM 5776 C C . LYS A 1 711 ? 23.827 75.261 -23.428 1.00 12.46 ? 711 LYS A C 1 ATOM 5777 O O . LYS A 1 711 ? 24.169 74.282 -22.719 1.00 15.42 ? 711 LYS A O 1 ATOM 5778 C CB . LYS A 1 711 ? 22.029 74.460 -24.927 1.00 15.68 ? 711 LYS A CB 1 ATOM 5779 C CG . LYS A 1 711 ? 20.965 75.435 -24.415 1.00 20.01 ? 711 LYS A CG 1 ATOM 5780 C CD . LYS A 1 711 ? 19.534 74.867 -24.533 1.00 25.83 ? 711 LYS A CD 1 ATOM 5781 C CE . LYS A 1 711 ? 19.130 74.750 -26.013 1.00 24.25 ? 711 LYS A CE 1 ATOM 5782 N NZ . LYS A 1 711 ? 17.775 74.108 -26.107 1.00 28.68 ? 711 LYS A NZ 1 ATOM 5783 N N . PHE A 1 712 ? 23.720 76.490 -22.927 1.00 10.91 ? 712 PHE A N 1 ATOM 5784 C CA . PHE A 1 712 ? 23.949 76.808 -21.552 1.00 11.25 ? 712 PHE A CA 1 ATOM 5785 C C . PHE A 1 712 ? 22.662 77.134 -20.862 1.00 10.39 ? 712 PHE A C 1 ATOM 5786 O O . PHE A 1 712 ? 21.814 77.888 -21.430 1.00 12.70 ? 712 PHE A O 1 ATOM 5787 C CB . PHE A 1 712 ? 24.973 77.977 -21.384 1.00 12.51 ? 712 PHE A CB 1 ATOM 5788 C CG . PHE A 1 712 ? 26.389 77.568 -21.736 1.00 12.18 ? 712 PHE A CG 1 ATOM 5789 C CD1 . PHE A 1 712 ? 26.865 77.583 -23.069 1.00 12.36 ? 712 PHE A CD1 1 ATOM 5790 C CD2 . PHE A 1 712 ? 27.229 77.103 -20.697 1.00 12.58 ? 712 PHE A CD2 1 ATOM 5791 C CE1 . PHE A 1 712 ? 28.161 77.151 -23.377 1.00 11.36 ? 712 PHE A CE1 1 ATOM 5792 C CE2 . PHE A 1 712 ? 28.505 76.678 -20.980 1.00 12.23 ? 712 PHE A CE2 1 ATOM 5793 C CZ . PHE A 1 712 ? 28.988 76.693 -22.290 1.00 11.75 ? 712 PHE A CZ 1 ATOM 5794 N N . LEU A 1 713 ? 22.435 76.598 -19.702 1.00 10.10 ? 713 LEU A N 1 ATOM 5795 C CA . LEU A 1 713 ? 21.215 76.793 -18.923 1.00 11.20 ? 713 LEU A CA 1 ATOM 5796 C C . LEU A 1 713 ? 21.519 77.078 -17.474 1.00 11.65 ? 713 LEU A C 1 ATOM 5797 O O . LEU A 1 713 ? 22.720 76.994 -17.045 1.00 11.76 ? 713 LEU A O 1 ATOM 5798 C CB . LEU A 1 713 ? 20.295 75.542 -19.010 1.00 11.15 ? 713 LEU A CB 1 ATOM 5799 C CG . LEU A 1 713 ? 19.951 75.129 -20.439 1.00 12.09 ? 713 LEU A CG 1 ATOM 5800 C CD1 . LEU A 1 713 ? 20.791 73.954 -20.935 1.00 13.86 ? 713 LEU A CD1 1 ATOM 5801 C CD2 . LEU A 1 713 ? 18.469 74.683 -20.532 1.00 13.90 ? 713 LEU A CD2 1 ATOM 5802 N N . LYS A 1 714 ? 20.531 77.456 -16.685 1.00 11.02 ? 714 LYS A N 1 ATOM 5803 C CA . LYS A 1 714 ? 20.726 77.722 -15.290 1.00 12.56 ? 714 LYS A CA 1 ATOM 5804 C C . LYS A 1 714 ? 19.695 77.066 -14.419 1.00 13.70 ? 714 LYS A C 1 ATOM 5805 O O . LYS A 1 714 ? 18.496 77.021 -14.778 1.00 14.72 ? 714 LYS A O 1 ATOM 5806 C CB . LYS A 1 714 ? 20.706 79.233 -14.968 1.00 18.40 ? 714 LYS A CB 1 ATOM 5807 C CG . LYS A 1 714 ? 19.731 80.048 -15.707 1.00 28.32 ? 714 LYS A CG 1 ATOM 5808 C CD . LYS A 1 714 ? 19.981 81.567 -15.390 1.00 32.66 ? 714 LYS A CD 1 ATOM 5809 C CE . LYS A 1 714 ? 21.471 81.983 -15.536 1.00 39.05 ? 714 LYS A CE 1 ATOM 5810 N NZ . LYS A 1 714 ? 21.704 83.472 -15.474 1.00 39.35 ? 714 LYS A NZ 1 ATOM 5811 N N . TYR A 1 715 ? 20.159 76.520 -13.295 1.00 11.24 ? 715 TYR A N 1 ATOM 5812 C CA . TYR A 1 715 ? 19.285 76.003 -12.288 1.00 10.83 ? 715 TYR A CA 1 ATOM 5813 C C . TYR A 1 715 ? 19.236 77.059 -11.195 1.00 13.88 ? 715 TYR A C 1 ATOM 5814 O O . TYR A 1 715 ? 20.215 77.781 -10.945 1.00 13.76 ? 715 TYR A O 1 ATOM 5815 C CB . TYR A 1 715 ? 19.831 74.705 -11.633 1.00 11.26 ? 715 TYR A CB 1 ATOM 5816 C CG . TYR A 1 715 ? 19.760 73.525 -12.512 1.00 10.25 ? 715 TYR A CG 1 ATOM 5817 C CD1 . TYR A 1 715 ? 20.862 73.078 -13.257 1.00 10.79 ? 715 TYR A CD1 1 ATOM 5818 C CD2 . TYR A 1 715 ? 18.569 72.781 -12.592 1.00 11.13 ? 715 TYR A CD2 1 ATOM 5819 C CE1 . TYR A 1 715 ? 20.804 71.927 -14.041 1.00 11.02 ? 715 TYR A CE1 1 ATOM 5820 C CE2 . TYR A 1 715 ? 18.483 71.622 -13.370 1.00 11.06 ? 715 TYR A CE2 1 ATOM 5821 C CZ . TYR A 1 715 ? 19.598 71.168 -14.099 1.00 9.85 ? 715 TYR A CZ 1 ATOM 5822 O OH . TYR A 1 715 ? 19.499 70.020 -14.834 1.00 11.67 ? 715 TYR A OH 1 ATOM 5823 N N . GLY A 1 716 ? 18.133 77.138 -10.461 1.00 11.87 ? 716 GLY A N 1 ATOM 5824 C CA . GLY A 1 716 ? 17.952 78.068 -9.354 1.00 12.27 ? 716 GLY A CA 1 ATOM 5825 C C . GLY A 1 716 ? 17.825 77.290 -8.030 1.00 13.63 ? 716 GLY A C 1 ATOM 5826 O O . GLY A 1 716 ? 18.123 76.051 -7.972 1.00 15.85 ? 716 GLY A O 1 ATOM 5827 N N . VAL A 1 717 ? 17.339 77.949 -6.995 1.00 13.39 ? 717 VAL A N 1 ATOM 5828 C CA . VAL A 1 717 ? 17.206 77.389 -5.662 1.00 14.63 ? 717 VAL A CA 1 ATOM 5829 C C . VAL A 1 717 ? 15.743 77.541 -5.230 1.00 16.02 ? 717 VAL A C 1 ATOM 5830 O O . VAL A 1 717 ? 15.077 78.501 -5.648 1.00 18.17 ? 717 VAL A O 1 ATOM 5831 C CB . VAL A 1 717 ? 18.125 78.156 -4.701 1.00 15.32 ? 717 VAL A CB 1 ATOM 5832 C CG1 . VAL A 1 717 ? 17.919 77.763 -3.278 1.00 20.05 ? 717 VAL A CG1 1 ATOM 5833 C CG2 . VAL A 1 717 ? 19.586 77.910 -5.083 1.00 14.95 ? 717 VAL A CG2 1 ATOM 5834 N N . ARG A 1 718 ? 15.265 76.655 -4.383 1.00 13.65 ? 718 ARG A N 1 ATOM 5835 C CA . ARG A 1 718 ? 13.862 76.675 -3.917 1.00 15.21 ? 718 ARG A CA 1 ATOM 5836 C C . ARG A 1 718 ? 13.603 77.846 -3.027 1.00 18.98 ? 718 ARG A C 1 ATOM 5837 O O . ARG A 1 718 ? 14.435 78.201 -2.227 1.00 21.91 ? 718 ARG A O 1 ATOM 5838 C CB . ARG A 1 718 ? 13.528 75.363 -3.209 1.00 15.00 ? 718 ARG A CB 1 ATOM 5839 C CG . ARG A 1 718 ? 13.599 74.237 -4.198 1.00 13.73 ? 718 ARG A CG 1 ATOM 5840 C CD . ARG A 1 718 ? 13.597 72.863 -3.484 1.00 15.87 ? 718 ARG A CD 1 ATOM 5841 N NE . ARG A 1 718 ? 13.824 71.861 -4.489 1.00 15.13 ? 718 ARG A NE 1 ATOM 5842 C CZ . ARG A 1 718 ? 13.807 70.550 -4.245 1.00 16.22 ? 718 ARG A CZ 1 ATOM 5843 N NH1 . ARG A 1 718 ? 13.535 70.096 -3.020 1.00 15.26 ? 718 ARG A NH1 1 ATOM 5844 N NH2 . ARG A 1 718 ? 14.144 69.720 -5.216 1.00 17.95 ? 718 ARG A NH2 1 ATOM 5845 N N . SER A 1 719 ? 12.411 78.442 -3.154 1.00 20.50 ? 719 SER A N 1 ATOM 5846 C CA . SER A 1 719 ? 12.078 79.607 -2.323 1.00 26.17 ? 719 SER A CA 1 ATOM 5847 C C . SER A 1 719 ? 11.467 79.243 -0.976 1.00 30.01 ? 719 SER A C 1 ATOM 5848 O O . SER A 1 719 ? 11.344 80.082 -0.102 1.00 33.64 ? 719 SER A O 1 ATOM 5849 C CB . SER A 1 719 ? 11.154 80.561 -3.093 1.00 24.49 ? 719 SER A CB 1 ATOM 5850 O OG . SER A 1 719 ? 10.017 79.862 -3.495 1.00 29.85 ? 719 SER A OG 1 ATOM 5851 N N . HIS A 1 720 ? 11.048 77.997 -0.835 1.00 32.15 ? 720 HIS A N 1 ATOM 5852 C CA . HIS A 1 720 ? 10.544 77.495 0.430 1.00 34.80 ? 720 HIS A CA 1 ATOM 5853 C C . HIS A 1 720 ? 11.091 76.051 0.485 1.00 34.26 ? 720 HIS A C 1 ATOM 5854 O O . HIS A 1 720 ? 11.455 75.458 -0.541 1.00 34.39 ? 720 HIS A O 1 ATOM 5855 C CB . HIS A 1 720 ? 9.010 77.562 0.478 1.00 37.53 ? 720 HIS A CB 1 ATOM 5856 C CG . HIS A 1 720 ? 8.334 76.767 -0.591 1.00 40.71 ? 720 HIS A CG 1 ATOM 5857 N ND1 . HIS A 1 720 ? 8.041 75.425 -0.447 1.00 43.49 ? 720 HIS A ND1 1 ATOM 5858 C CD2 . HIS A 1 720 ? 7.939 77.113 -1.842 1.00 43.31 ? 720 HIS A CD2 1 ATOM 5859 C CE1 . HIS A 1 720 ? 7.498 74.978 -1.567 1.00 45.27 ? 720 HIS A CE1 1 ATOM 5860 N NE2 . HIS A 1 720 ? 7.427 75.981 -2.429 1.00 44.27 ? 720 HIS A NE2 1 ATOM 5861 N N . GLY A 1 721 ? 11.185 75.488 1.675 1.00 31.85 ? 721 GLY A N 1 ATOM 5862 C CA . GLY A 1 721 ? 11.750 74.162 1.737 1.00 28.47 ? 721 GLY A CA 1 ATOM 5863 C C . GLY A 1 721 ? 13.276 74.227 1.813 1.00 26.70 ? 721 GLY A C 1 ATOM 5864 O O . GLY A 1 721 ? 13.905 75.273 2.067 1.00 23.07 ? 721 GLY A O 1 ATOM 5865 N N . ASP A 1 722 ? 13.882 73.090 1.518 1.00 21.12 ? 722 ASP A N 1 ATOM 5866 C CA . ASP A 1 722 ? 15.327 72.991 1.688 1.00 18.92 ? 722 ASP A CA 1 ATOM 5867 C C . ASP A 1 722 ? 16.095 73.664 0.582 1.00 15.74 ? 722 ASP A C 1 ATOM 5868 O O . ASP A 1 722 ? 15.751 73.574 -0.570 1.00 16.91 ? 722 ASP A O 1 ATOM 5869 C CB . ASP A 1 722 ? 15.717 71.522 1.777 1.00 16.84 ? 722 ASP A CB 1 ATOM 5870 C CG . ASP A 1 722 ? 15.159 70.803 3.047 1.00 18.49 ? 722 ASP A CG 1 ATOM 5871 O OD1 . ASP A 1 722 ? 14.965 69.556 2.931 1.00 19.14 ? 722 ASP A OD1 1 ATOM 5872 O OD2 . ASP A 1 722 ? 14.955 71.434 4.152 1.00 20.29 ? 722 ASP A OD2 1 ATOM 5873 N N . ARG A 1 723 ? 17.189 74.313 0.990 1.00 15.00 ? 723 ARG A N 1 ATOM 5874 C CA . ARG A 1 723 ? 18.040 75.026 0.048 1.00 14.34 ? 723 ARG A CA 1 ATOM 5875 C C . ARG A 1 723 ? 19.339 74.318 -0.325 1.00 14.00 ? 723 ARG A C 1 ATOM 5876 O O . ARG A 1 723 ? 19.956 73.654 0.508 1.00 13.86 ? 723 ARG A O 1 ATOM 5877 C CB . ARG A 1 723 ? 18.427 76.374 0.643 1.00 16.58 ? 723 ARG A CB 1 ATOM 5878 C CG . ARG A 1 723 ? 17.197 77.170 1.101 1.00 24.52 ? 723 ARG A CG 1 ATOM 5879 C CD . ARG A 1 723 ? 17.502 78.626 1.327 1.00 33.35 ? 723 ARG A CD 1 ATOM 5880 N NE . ARG A 1 723 ? 16.240 79.285 1.599 1.00 39.68 ? 723 ARG A NE 1 ATOM 5881 C CZ . ARG A 1 723 ? 16.110 80.521 2.061 1.00 41.68 ? 723 ARG A CZ 1 ATOM 5882 N NH1 . ARG A 1 723 ? 17.189 81.270 2.311 1.00 41.99 ? 723 ARG A NH1 1 ATOM 5883 N NH2 . ARG A 1 723 ? 14.887 80.993 2.289 1.00 39.20 ? 723 ARG A NH2 1 ATOM 5884 N N . SER A 1 724 ? 19.693 74.465 -1.601 1.00 11.90 ? 724 SER A N 1 ATOM 5885 C CA . SER A 1 724 ? 20.953 73.952 -2.110 1.00 11.10 ? 724 SER A CA 1 ATOM 5886 C C . SER A 1 724 ? 22.060 74.657 -1.337 1.00 12.37 ? 724 SER A C 1 ATOM 5887 O O . SER A 1 724 ? 21.950 75.844 -0.972 1.00 15.23 ? 724 SER A O 1 ATOM 5888 C CB . SER A 1 724 ? 21.124 74.327 -3.577 1.00 12.33 ? 724 SER A CB 1 ATOM 5889 O OG . SER A 1 724 ? 20.087 73.680 -4.281 1.00 12.29 ? 724 SER A OG 1 ATOM 5890 N N . GLY A 1 725 ? 23.189 73.949 -1.147 1.00 10.40 ? 725 GLY A N 1 ATOM 5891 C CA . GLY A 1 725 ? 24.359 74.531 -0.485 1.00 10.05 ? 725 GLY A CA 1 ATOM 5892 C C . GLY A 1 725 ? 25.592 73.772 -1.042 1.00 9.02 ? 725 GLY A C 1 ATOM 5893 O O . GLY A 1 725 ? 25.544 73.164 -2.126 1.00 9.88 ? 725 GLY A O 1 ATOM 5894 N N . ALA A 1 726 ? 26.716 73.868 -0.341 1.00 9.02 ? 726 ALA A N 1 ATOM 5895 C CA . ALA A 1 726 ? 27.931 73.205 -0.830 1.00 8.79 ? 726 ALA A CA 1 ATOM 5896 C C . ALA A 1 726 ? 27.796 71.709 -1.058 1.00 8.93 ? 726 ALA A C 1 ATOM 5897 O O . ALA A 1 726 ? 28.453 71.141 -1.944 1.00 8.86 ? 726 ALA A O 1 ATOM 5898 C CB . ALA A 1 726 ? 29.122 73.446 0.115 1.00 10.46 ? 726 ALA A CB 1 ATOM 5899 N N . TYR A 1 727 ? 26.969 71.058 -0.259 1.00 8.95 ? 727 TYR A N 1 ATOM 5900 C CA . TYR A 1 727 ? 26.779 69.593 -0.392 1.00 8.24 ? 727 TYR A CA 1 ATOM 5901 C C . TYR A 1 727 ? 25.612 69.181 -1.308 1.00 8.27 ? 727 TYR A C 1 ATOM 5902 O O . TYR A 1 727 ? 25.723 68.344 -2.170 1.00 8.81 ? 727 TYR A O 1 ATOM 5903 C CB . TYR A 1 727 ? 26.502 68.962 0.972 1.00 9.50 ? 727 TYR A CB 1 ATOM 5904 C CG . TYR A 1 727 ? 27.555 69.263 2.032 1.00 9.29 ? 727 TYR A CG 1 ATOM 5905 C CD1 . TYR A 1 727 ? 27.481 70.432 2.796 1.00 10.37 ? 727 TYR A CD1 1 ATOM 5906 C CD2 . TYR A 1 727 ? 28.608 68.362 2.294 1.00 9.78 ? 727 TYR A CD2 1 ATOM 5907 C CE1 . TYR A 1 727 ? 28.426 70.675 3.802 1.00 9.27 ? 727 TYR A CE1 1 ATOM 5908 C CE2 . TYR A 1 727 ? 29.554 68.622 3.296 1.00 8.98 ? 727 TYR A CE2 1 ATOM 5909 C CZ . TYR A 1 727 ? 29.457 69.755 4.038 1.00 9.63 ? 727 TYR A CZ 1 ATOM 5910 O OH . TYR A 1 727 ? 30.282 70.003 5.121 1.00 10.46 ? 727 TYR A OH 1 ATOM 5911 N N . LEU A 1 728 ? 24.469 69.827 -1.009 1.00 9.72 ? 728 LEU A N 1 ATOM 5912 C CA . LEU A 1 728 ? 23.186 69.451 -1.635 1.00 9.33 ? 728 LEU A CA 1 ATOM 5913 C C . LEU A 1 728 ? 22.820 70.204 -2.885 1.00 9.43 ? 728 LEU A C 1 ATOM 5914 O O . LEU A 1 728 ? 23.002 71.423 -2.949 1.00 10.58 ? 728 LEU A O 1 ATOM 5915 C CB . LEU A 1 728 ? 21.996 69.681 -0.636 1.00 10.66 ? 728 LEU A CB 1 ATOM 5916 C CG . LEU A 1 728 ? 22.161 69.050 0.750 1.00 9.78 ? 728 LEU A CG 1 ATOM 5917 C CD1 . LEU A 1 728 ? 20.837 69.267 1.563 1.00 12.18 ? 728 LEU A CD1 1 ATOM 5918 C CD2 . LEU A 1 728 ? 22.490 67.576 0.700 1.00 13.11 ? 728 LEU A CD2 1 ATOM 5919 N N . PHE A 1 729 ? 22.283 69.490 -3.872 1.00 9.59 ? 729 PHE A N 1 ATOM 5920 C CA . PHE A 1 729 ? 21.737 70.095 -5.082 1.00 10.41 ? 729 PHE A CA 1 ATOM 5921 C C . PHE A 1 729 ? 20.198 69.883 -4.979 1.00 11.22 ? 729 PHE A C 1 ATOM 5922 O O . PHE A 1 729 ? 19.715 68.741 -5.070 1.00 10.71 ? 729 PHE A O 1 ATOM 5923 C CB . PHE A 1 729 ? 22.298 69.332 -6.288 1.00 10.24 ? 729 PHE A CB 1 ATOM 5924 C CG . PHE A 1 729 ? 21.759 69.795 -7.646 1.00 9.34 ? 729 PHE A CG 1 ATOM 5925 C CD1 . PHE A 1 729 ? 21.657 68.901 -8.680 1.00 9.91 ? 729 PHE A CD1 1 ATOM 5926 C CD2 . PHE A 1 729 ? 21.441 71.154 -7.901 1.00 10.21 ? 729 PHE A CD2 1 ATOM 5927 C CE1 . PHE A 1 729 ? 21.257 69.285 -9.932 1.00 9.25 ? 729 PHE A CE1 1 ATOM 5928 C CE2 . PHE A 1 729 ? 21.026 71.560 -9.181 1.00 9.26 ? 729 PHE A CE2 1 ATOM 5929 C CZ . PHE A 1 729 ? 20.934 70.632 -10.181 1.00 10.43 ? 729 PHE A CZ 1 ATOM 5930 N N . LEU A 1 730 ? 19.486 71.000 -4.794 1.00 10.69 ? 730 LEU A N 1 ATOM 5931 C CA . LEU A 1 730 ? 17.999 70.975 -4.616 1.00 12.94 ? 730 LEU A CA 1 ATOM 5932 C C . LEU A 1 730 ? 17.420 71.987 -5.592 1.00 10.38 ? 730 LEU A C 1 ATOM 5933 O O . LEU A 1 730 ? 16.961 73.073 -5.184 1.00 12.06 ? 730 LEU A O 1 ATOM 5934 C CB . LEU A 1 730 ? 17.644 71.327 -3.159 1.00 12.64 ? 730 LEU A CB 1 ATOM 5935 C CG . LEU A 1 730 ? 18.073 70.230 -2.160 1.00 12.77 ? 730 LEU A CG 1 ATOM 5936 C CD1 . LEU A 1 730 ? 18.082 70.772 -0.748 1.00 15.13 ? 730 LEU A CD1 1 ATOM 5937 C CD2 . LEU A 1 730 ? 17.093 69.051 -2.252 1.00 16.02 ? 730 LEU A CD2 1 ATOM 5938 N N . PRO A 1 731 ? 17.458 71.663 -6.878 1.00 11.62 ? 731 PRO A N 1 ATOM 5939 C CA . PRO A 1 731 ? 16.948 72.619 -7.869 1.00 12.50 ? 731 PRO A CA 1 ATOM 5940 C C . PRO A 1 731 ? 15.482 72.924 -7.774 1.00 12.87 ? 731 PRO A C 1 ATOM 5941 O O . PRO A 1 731 ? 14.686 72.103 -7.314 1.00 13.38 ? 731 PRO A O 1 ATOM 5942 C CB . PRO A 1 731 ? 17.294 71.942 -9.193 1.00 13.17 ? 731 PRO A CB 1 ATOM 5943 C CG . PRO A 1 731 ? 17.197 70.471 -8.887 1.00 13.40 ? 731 PRO A CG 1 ATOM 5944 C CD . PRO A 1 731 ? 17.771 70.366 -7.500 1.00 11.67 ? 731 PRO A CD 1 ATOM 5945 N N . ASN A 1 732 ? 15.147 74.127 -8.234 1.00 13.79 ? 732 ASN A N 1 ATOM 5946 C CA . ASN A 1 732 ? 13.705 74.531 -8.289 1.00 14.64 ? 732 ASN A CA 1 ATOM 5947 C C . ASN A 1 732 ? 13.211 74.173 -9.679 1.00 15.76 ? 732 ASN A C 1 ATOM 5948 O O . ASN A 1 732 ? 12.775 75.040 -10.458 1.00 19.83 ? 732 ASN A O 1 ATOM 5949 C CB . ASN A 1 732 ? 13.565 76.026 -7.966 1.00 18.61 ? 732 ASN A CB 1 ATOM 5950 C CG . ASN A 1 732 ? 14.268 76.905 -8.940 1.00 19.69 ? 732 ASN A CG 1 ATOM 5951 O OD1 . ASN A 1 732 ? 15.253 76.546 -9.555 1.00 21.01 ? 732 ASN A OD1 1 ATOM 5952 N ND2 . ASN A 1 732 ? 13.729 78.134 -9.119 1.00 23.96 ? 732 ASN A ND2 1 ATOM 5953 N N . GLY A 1 733 ? 13.289 72.905 -10.028 1.00 14.61 ? 733 GLY A N 1 ATOM 5954 C CA . GLY A 1 733 ? 12.838 72.420 -11.321 1.00 15.88 ? 733 GLY A CA 1 ATOM 5955 C C . GLY A 1 733 ? 13.908 72.348 -12.413 1.00 14.38 ? 733 GLY A C 1 ATOM 5956 O O . GLY A 1 733 ? 15.093 72.708 -12.146 1.00 13.98 ? 733 GLY A O 1 ATOM 5957 N N . PRO A 1 734 ? 13.581 71.866 -13.603 1.00 13.23 ? 734 PRO A N 1 ATOM 5958 C CA . PRO A 1 734 ? 14.522 71.774 -14.716 1.00 13.19 ? 734 PRO A CA 1 ATOM 5959 C C . PRO A 1 734 ? 15.132 73.145 -15.012 1.00 14.03 ? 734 PRO A C 1 ATOM 5960 O O . PRO A 1 734 ? 14.545 74.216 -14.773 1.00 14.22 ? 734 PRO A O 1 ATOM 5961 C CB . PRO A 1 734 ? 13.673 71.297 -15.880 1.00 15.76 ? 734 PRO A CB 1 ATOM 5962 C CG . PRO A 1 734 ? 12.535 70.526 -15.171 1.00 20.47 ? 734 PRO A CG 1 ATOM 5963 C CD . PRO A 1 734 ? 12.258 71.290 -13.942 1.00 15.72 ? 734 PRO A CD 1 ATOM 5964 N N . ALA A 1 735 ? 16.328 73.086 -15.594 1.00 13.20 ? 735 ALA A N 1 ATOM 5965 C CA . ALA A 1 735 ? 17.066 74.299 -15.942 1.00 13.05 ? 735 ALA A CA 1 ATOM 5966 C C . ALA A 1 735 ? 16.380 75.137 -17.033 1.00 13.51 ? 735 ALA A C 1 ATOM 5967 O O . ALA A 1 735 ? 15.666 74.618 -17.874 1.00 15.83 ? 735 ALA A O 1 ATOM 5968 C CB . ALA A 1 735 ? 18.513 73.882 -16.338 1.00 12.89 ? 735 ALA A CB 1 ATOM 5969 N N . SER A 1 736 ? 16.640 76.433 -16.942 1.00 14.62 ? 736 SER A N 1 ATOM 5970 C CA . SER A 1 736 ? 16.086 77.428 -17.881 1.00 14.88 ? 736 SER A CA 1 ATOM 5971 C C . SER A 1 736 ? 17.217 77.914 -18.731 1.00 15.53 ? 736 SER A C 1 ATOM 5972 O O . SER A 1 736 ? 18.313 78.146 -18.234 1.00 15.28 ? 736 SER A O 1 ATOM 5973 C CB . SER A 1 736 ? 15.508 78.588 -17.089 1.00 16.83 ? 736 SER A CB 1 ATOM 5974 O OG . SER A 1 736 ? 14.546 78.155 -16.150 1.00 28.68 ? 736 SER A OG 1 ATOM 5975 N N . PRO A 1 737 ? 16.983 78.164 -20.027 1.00 17.33 ? 737 PRO A N 1 ATOM 5976 C CA . PRO A 1 737 ? 18.082 78.635 -20.910 1.00 19.44 ? 737 PRO A CA 1 ATOM 5977 C C . PRO A 1 737 ? 18.676 79.979 -20.470 1.00 18.18 ? 737 PRO A C 1 ATOM 5978 O O . PRO A 1 737 ? 17.939 80.864 -19.987 1.00 20.71 ? 737 PRO A O 1 ATOM 5979 C CB . PRO A 1 737 ? 17.419 78.782 -22.291 1.00 24.24 ? 737 PRO A CB 1 ATOM 5980 C CG . PRO A 1 737 ? 16.219 77.823 -22.212 1.00 22.91 ? 737 PRO A CG 1 ATOM 5981 C CD . PRO A 1 737 ? 15.722 77.989 -20.776 1.00 19.42 ? 737 PRO A CD 1 ATOM 5982 N N . VAL A 1 738 ? 20.014 80.115 -20.529 1.00 16.28 ? 738 VAL A N 1 ATOM 5983 C CA . VAL A 1 738 ? 20.639 81.435 -20.254 1.00 15.73 ? 738 VAL A CA 1 ATOM 5984 C C . VAL A 1 738 ? 20.222 82.330 -21.451 1.00 16.96 ? 738 VAL A C 1 ATOM 5985 O O . VAL A 1 738 ? 20.294 81.912 -22.598 1.00 17.96 ? 738 VAL A O 1 ATOM 5986 C CB . VAL A 1 738 ? 22.185 81.295 -20.202 1.00 16.24 ? 738 VAL A CB 1 ATOM 5987 C CG1 . VAL A 1 738 ? 22.868 82.730 -20.189 1.00 16.91 ? 738 VAL A CG1 1 ATOM 5988 C CG2 . VAL A 1 738 ? 22.596 80.458 -18.945 1.00 15.56 ? 738 VAL A CG2 1 ATOM 5989 N N . GLU A 1 739 ? 19.767 83.539 -21.154 1.00 19.78 ? 739 GLU A N 1 ATOM 5990 C CA . GLU A 1 739 ? 19.391 84.468 -22.233 1.00 20.29 ? 739 GLU A CA 1 ATOM 5991 C C . GLU A 1 739 ? 20.724 84.997 -22.804 1.00 16.62 ? 739 GLU A C 1 ATOM 5992 O O . GLU A 1 739 ? 21.500 85.645 -22.105 1.00 19.32 ? 739 GLU A O 1 ATOM 5993 C CB . GLU A 1 739 ? 18.592 85.619 -21.644 1.00 23.22 ? 739 GLU A CB 1 ATOM 5994 C CG . GLU A 1 739 ? 17.161 85.240 -21.355 1.00 32.04 ? 739 GLU A CG 1 ATOM 5995 C CD . GLU A 1 739 ? 16.222 86.454 -21.209 1.00 41.27 ? 739 GLU A CD 1 ATOM 5996 O OE1 . GLU A 1 739 ? 14.999 86.235 -20.999 1.00 43.45 ? 739 GLU A OE1 1 ATOM 5997 O OE2 . GLU A 1 739 ? 16.697 87.610 -21.310 1.00 44.37 ? 739 GLU A OE2 1 ATOM 5998 N N . LEU A 1 740 ? 20.966 84.724 -24.069 1.00 18.39 ? 740 LEU A N 1 ATOM 5999 C CA . LEU A 1 740 ? 22.265 85.068 -24.679 1.00 19.81 ? 740 LEU A CA 1 ATOM 6000 C C . LEU A 1 740 ? 22.443 86.444 -25.287 1.00 22.95 ? 740 LEU A C 1 ATOM 6001 O O . LEU A 1 740 ? 23.580 86.873 -25.420 1.00 24.77 ? 740 LEU A O 1 ATOM 6002 C CB . LEU A 1 740 ? 22.620 84.028 -25.736 1.00 22.54 ? 740 LEU A CB 1 ATOM 6003 C CG . LEU A 1 740 ? 22.632 82.567 -25.249 1.00 20.25 ? 740 LEU A CG 1 ATOM 6004 C CD1 . LEU A 1 740 ? 23.037 81.667 -26.393 1.00 19.04 ? 740 LEU A CD1 1 ATOM 6005 C CD2 . LEU A 1 740 ? 23.595 82.399 -24.018 1.00 20.44 ? 740 LEU A CD2 1 ATOM 6006 N N . GLY A 1 741 ? 21.337 87.123 -25.634 1.00 24.04 ? 741 GLY A N 1 ATOM 6007 C CA . GLY A 1 741 ? 21.464 88.431 -26.278 1.00 23.21 ? 741 GLY A CA 1 ATOM 6008 C C . GLY A 1 741 ? 22.037 88.203 -27.686 1.00 22.26 ? 741 GLY A C 1 ATOM 6009 O O . GLY A 1 741 ? 21.696 87.219 -28.326 1.00 24.03 ? 741 GLY A O 1 ATOM 6010 N N . GLN A 1 742 ? 22.874 89.113 -28.207 1.00 23.60 ? 742 GLN A N 1 ATOM 6011 C CA . GLN A 1 742 ? 23.502 88.887 -29.536 1.00 19.96 ? 742 GLN A CA 1 ATOM 6012 C C . GLN A 1 742 ? 25.007 88.872 -29.199 1.00 20.37 ? 742 GLN A C 1 ATOM 6013 O O . GLN A 1 742 ? 25.721 89.858 -29.345 1.00 21.33 ? 742 GLN A O 1 ATOM 6014 C CB . GLN A 1 742 ? 23.192 90.050 -30.497 1.00 28.58 ? 742 GLN A CB 1 ATOM 6015 C CG . GLN A 1 742 ? 23.618 89.739 -31.936 1.00 34.84 ? 742 GLN A CG 1 ATOM 6016 C CD . GLN A 1 742 ? 23.079 90.742 -32.975 1.00 43.03 ? 742 GLN A CD 1 ATOM 6017 O OE1 . GLN A 1 742 ? 22.819 90.367 -34.117 1.00 43.83 ? 742 GLN A OE1 1 ATOM 6018 N NE2 . GLN A 1 742 ? 22.925 92.019 -32.578 1.00 45.49 ? 742 GLN A NE2 1 ATOM 6019 N N . PRO A 1 743 ? 25.507 87.719 -28.768 1.00 16.52 ? 743 PRO A N 1 ATOM 6020 C CA . PRO A 1 743 ? 26.935 87.676 -28.385 1.00 13.73 ? 743 PRO A CA 1 ATOM 6021 C C . PRO A 1 743 ? 27.959 87.874 -29.489 1.00 15.03 ? 743 PRO A C 1 ATOM 6022 O O . PRO A 1 743 ? 27.715 87.638 -30.679 1.00 16.96 ? 743 PRO A O 1 ATOM 6023 C CB . PRO A 1 743 ? 27.057 86.332 -27.692 1.00 16.32 ? 743 PRO A CB 1 ATOM 6024 C CG . PRO A 1 743 ? 26.061 85.476 -28.415 1.00 15.62 ? 743 PRO A CG 1 ATOM 6025 C CD . PRO A 1 743 ? 24.862 86.387 -28.736 1.00 14.79 ? 743 PRO A CD 1 ATOM 6026 N N . VAL A 1 744 ? 29.118 88.360 -29.065 1.00 12.01 ? 744 VAL A N 1 ATOM 6027 C CA . VAL A 1 744 ? 30.253 88.580 -29.977 1.00 11.45 ? 744 VAL A CA 1 ATOM 6028 C C . VAL A 1 744 ? 30.961 87.241 -30.197 1.00 10.60 ? 744 VAL A C 1 ATOM 6029 O O . VAL A 1 744 ? 31.280 86.540 -29.212 1.00 12.19 ? 744 VAL A O 1 ATOM 6030 C CB . VAL A 1 744 ? 31.219 89.596 -29.359 1.00 11.72 ? 744 VAL A CB 1 ATOM 6031 C CG1 . VAL A 1 744 ? 32.435 89.783 -30.250 1.00 13.53 ? 744 VAL A CG1 1 ATOM 6032 C CG2 . VAL A 1 744 ? 30.476 90.958 -29.161 1.00 15.65 ? 744 VAL A CG2 1 ATOM 6033 N N . VAL A 1 745 ? 31.184 86.880 -31.423 1.00 10.99 ? 745 VAL A N 1 ATOM 6034 C CA . VAL A 1 745 ? 31.815 85.622 -31.814 1.00 10.92 ? 745 VAL A CA 1 ATOM 6035 C C . VAL A 1 745 ? 33.094 85.855 -32.547 1.00 10.90 ? 745 VAL A C 1 ATOM 6036 O O . VAL A 1 745 ? 33.118 86.631 -33.538 1.00 12.73 ? 745 VAL A O 1 ATOM 6037 C CB . VAL A 1 745 ? 30.851 84.808 -32.736 1.00 10.26 ? 745 VAL A CB 1 ATOM 6038 C CG1 . VAL A 1 745 ? 31.467 83.490 -33.163 1.00 12.17 ? 745 VAL A CG1 1 ATOM 6039 C CG2 . VAL A 1 745 ? 29.522 84.562 -32.018 1.00 10.95 ? 745 VAL A CG2 1 ATOM 6040 N N . LEU A 1 746 ? 34.190 85.197 -32.165 1.00 10.28 ? 746 LEU A N 1 ATOM 6041 C CA . LEU A 1 746 ? 35.457 85.347 -32.815 1.00 10.06 ? 746 LEU A CA 1 ATOM 6042 C C . LEU A 1 746 ? 35.867 84.061 -33.490 1.00 10.52 ? 746 LEU A C 1 ATOM 6043 O O . LEU A 1 746 ? 35.928 82.989 -32.801 1.00 10.25 ? 746 LEU A O 1 ATOM 6044 C CB . LEU A 1 746 ? 36.482 85.728 -31.739 1.00 11.91 ? 746 LEU A CB 1 ATOM 6045 C CG . LEU A 1 746 ? 37.956 85.694 -32.198 1.00 13.41 ? 746 LEU A CG 1 ATOM 6046 C CD1 . LEU A 1 746 ? 38.235 86.810 -33.259 1.00 15.93 ? 746 LEU A CD1 1 ATOM 6047 C CD2 . LEU A 1 746 ? 38.859 85.873 -30.949 1.00 16.81 ? 746 LEU A CD2 1 ATOM 6048 N N . VAL A 1 747 ? 36.155 84.082 -34.759 1.00 10.12 ? 747 VAL A N 1 ATOM 6049 C CA . VAL A 1 747 ? 36.567 82.913 -35.515 1.00 9.76 ? 747 VAL A CA 1 ATOM 6050 C C . VAL A 1 747 ? 38.005 83.033 -35.948 1.00 11.39 ? 747 VAL A C 1 ATOM 6051 O O . VAL A 1 747 ? 38.358 84.000 -36.658 1.00 13.37 ? 747 VAL A O 1 ATOM 6052 C CB . VAL A 1 747 ? 35.661 82.749 -36.768 1.00 11.05 ? 747 VAL A CB 1 ATOM 6053 C CG1 . VAL A 1 747 ? 36.026 81.455 -37.508 1.00 12.15 ? 747 VAL A CG1 1 ATOM 6054 C CG2 . VAL A 1 747 ? 34.179 82.751 -36.345 1.00 11.94 ? 747 VAL A CG2 1 ATOM 6055 N N . THR A 1 748 ? 38.875 82.113 -35.559 1.00 10.89 ? 748 THR A N 1 ATOM 6056 C CA . THR A 1 748 ? 40.244 82.123 -35.999 1.00 12.26 ? 748 THR A CA 1 ATOM 6057 C C . THR A 1 748 ? 40.453 80.924 -36.866 1.00 12.09 ? 748 THR A C 1 ATOM 6058 O O . THR A 1 748 ? 40.106 79.797 -36.424 1.00 13.54 ? 748 THR A O 1 ATOM 6059 C CB . THR A 1 748 ? 41.146 82.150 -34.751 1.00 13.26 ? 748 THR A CB 1 ATOM 6060 O OG1 . THR A 1 748 ? 40.924 83.378 -34.035 1.00 14.95 ? 748 THR A OG1 1 ATOM 6061 C CG2 . THR A 1 748 ? 42.598 82.091 -35.147 1.00 14.83 ? 748 THR A CG2 1 ATOM 6062 N N . LYS A 1 749 ? 40.971 81.095 -38.087 1.00 11.75 ? 749 LYS A N 1 ATOM 6063 C CA . LYS A 1 749 ? 41.142 79.969 -39.003 1.00 11.89 ? 749 LYS A CA 1 ATOM 6064 C C . LYS A 1 749 ? 42.558 79.825 -39.401 1.00 13.18 ? 749 LYS A C 1 ATOM 6065 O O . LYS A 1 749 ? 43.170 80.744 -39.985 1.00 12.68 ? 749 LYS A O 1 ATOM 6066 C CB . LYS A 1 749 ? 40.284 80.175 -40.248 1.00 14.20 ? 749 LYS A CB 1 ATOM 6067 C CG . LYS A 1 749 ? 40.424 79.049 -41.255 1.00 18.90 ? 749 LYS A CG 1 ATOM 6068 C CD . LYS A 1 749 ? 39.466 79.267 -42.450 1.00 22.50 ? 749 LYS A CD 1 ATOM 6069 C CE . LYS A 1 749 ? 39.808 78.352 -43.607 1.00 28.76 ? 749 LYS A CE 1 ATOM 6070 N NZ . LYS A 1 749 ? 38.960 78.837 -44.778 1.00 37.97 ? 749 LYS A NZ 1 ATOM 6071 N N . GLY A 1 750 ? 43.127 78.658 -39.090 1.00 11.65 ? 750 GLY A N 1 ATOM 6072 C CA . GLY A 1 750 ? 44.522 78.416 -39.406 1.00 14.13 ? 750 GLY A CA 1 ATOM 6073 C C . GLY A 1 750 ? 44.740 77.040 -39.972 1.00 12.07 ? 750 GLY A C 1 ATOM 6074 O O . GLY A 1 750 ? 43.824 76.180 -39.870 1.00 15.10 ? 750 GLY A O 1 ATOM 6075 N N . LYS A 1 751 ? 45.940 76.840 -40.532 1.00 13.53 ? 751 LYS A N 1 ATOM 6076 C CA . LYS A 1 751 ? 46.225 75.535 -41.109 1.00 13.56 ? 751 LYS A CA 1 ATOM 6077 C C . LYS A 1 751 ? 46.361 74.445 -40.048 1.00 12.77 ? 751 LYS A C 1 ATOM 6078 O O . LYS A 1 751 ? 45.983 73.301 -40.312 1.00 14.16 ? 751 LYS A O 1 ATOM 6079 C CB . LYS A 1 751 ? 47.490 75.601 -41.962 1.00 18.01 ? 751 LYS A CB 1 ATOM 6080 C CG . LYS A 1 751 ? 47.811 74.248 -42.558 1.00 28.01 ? 751 LYS A CG 1 ATOM 6081 C CD . LYS A 1 751 ? 48.425 74.313 -43.962 1.00 34.34 ? 751 LYS A CD 1 ATOM 6082 C CE . LYS A 1 751 ? 48.796 72.896 -44.430 1.00 37.54 ? 751 LYS A CE 1 ATOM 6083 N NZ . LYS A 1 751 ? 47.629 71.924 -44.341 1.00 44.01 ? 751 LYS A NZ 1 ATOM 6084 N N . LEU A 1 752 ? 46.934 74.788 -38.897 1.00 12.21 ? 752 LEU A N 1 ATOM 6085 C CA . LEU A 1 752 ? 47.147 73.808 -37.796 1.00 10.89 ? 752 LEU A CA 1 ATOM 6086 C C . LEU A 1 752 ? 46.065 73.845 -36.729 1.00 12.34 ? 752 LEU A C 1 ATOM 6087 O O . LEU A 1 752 ? 45.760 72.823 -36.123 1.00 12.48 ? 752 LEU A O 1 ATOM 6088 C CB . LEU A 1 752 ? 48.488 74.058 -37.091 1.00 12.49 ? 752 LEU A CB 1 ATOM 6089 C CG . LEU A 1 752 ? 49.685 73.998 -38.057 1.00 15.60 ? 752 LEU A CG 1 ATOM 6090 C CD1 . LEU A 1 752 ? 50.965 74.122 -37.233 1.00 16.06 ? 752 LEU A CD1 1 ATOM 6091 C CD2 . LEU A 1 752 ? 49.640 72.784 -38.954 1.00 19.35 ? 752 LEU A CD2 1 ATOM 6092 N N . GLU A 1 753 ? 45.433 74.993 -36.504 1.00 11.66 ? 753 GLU A N 1 ATOM 6093 C CA . GLU A 1 753 ? 44.468 75.134 -35.444 1.00 12.83 ? 753 GLU A CA 1 ATOM 6094 C C . GLU A 1 753 ? 43.468 76.236 -35.804 1.00 12.87 ? 753 GLU A C 1 ATOM 6095 O O . GLU A 1 753 ? 43.883 77.353 -36.218 1.00 13.43 ? 753 GLU A O 1 ATOM 6096 C CB . GLU A 1 753 ? 45.208 75.513 -34.121 1.00 12.18 ? 753 GLU A CB 1 ATOM 6097 C CG . GLU A 1 753 ? 44.256 75.704 -32.917 1.00 13.59 ? 753 GLU A CG 1 ATOM 6098 C CD . GLU A 1 753 ? 44.965 76.134 -31.645 1.00 19.51 ? 753 GLU A CD 1 ATOM 6099 O OE1 . GLU A 1 753 ? 45.228 77.347 -31.501 1.00 26.12 ? 753 GLU A OE1 1 ATOM 6100 O OE2 . GLU A 1 753 ? 45.232 75.241 -30.813 1.00 25.68 ? 753 GLU A OE2 1 ATOM 6101 N N . SER A 1 754 ? 42.209 75.949 -35.627 1.00 10.84 ? 754 SER A N 1 ATOM 6102 C CA . SER A 1 754 ? 41.134 76.909 -35.822 1.00 10.18 ? 754 SER A CA 1 ATOM 6103 C C . SER A 1 754 ? 40.271 76.919 -34.583 1.00 9.86 ? 754 SER A C 1 ATOM 6104 O O . SER A 1 754 ? 40.281 75.980 -33.747 1.00 11.56 ? 754 SER A O 1 ATOM 6105 C CB . SER A 1 754 ? 40.289 76.534 -37.015 1.00 12.17 ? 754 SER A CB 1 ATOM 6106 O OG . SER A 1 754 ? 41.072 76.692 -38.193 1.00 12.23 ? 754 SER A OG 1 ATOM 6107 N N . SER A 1 755 ? 39.487 77.970 -34.360 1.00 9.96 ? 755 SER A N 1 ATOM 6108 C CA . SER A 1 755 ? 38.625 78.021 -33.208 1.00 11.26 ? 755 SER A CA 1 ATOM 6109 C C . SER A 1 755 ? 37.472 78.978 -33.348 1.00 10.21 ? 755 SER A C 1 ATOM 6110 O O . SER A 1 755 ? 37.547 79.961 -34.171 1.00 11.17 ? 755 SER A O 1 ATOM 6111 C CB . SER A 1 755 ? 39.426 78.406 -31.961 1.00 16.08 ? 755 SER A CB 1 ATOM 6112 O OG . SER A 1 755 ? 39.930 79.707 -32.103 1.00 17.15 ? 755 SER A OG 1 ATOM 6113 N N . VAL A 1 756 ? 36.417 78.764 -32.599 1.00 9.18 ? 756 VAL A N 1 ATOM 6114 C CA . VAL A 1 756 ? 35.293 79.674 -32.511 1.00 10.15 ? 756 VAL A CA 1 ATOM 6115 C C . VAL A 1 756 ? 35.126 79.994 -31.026 1.00 9.85 ? 756 VAL A C 1 ATOM 6116 O O . VAL A 1 756 ? 34.953 79.039 -30.193 1.00 11.37 ? 756 VAL A O 1 ATOM 6117 C CB . VAL A 1 756 ? 33.990 79.046 -33.071 1.00 10.64 ? 756 VAL A CB 1 ATOM 6118 C CG1 . VAL A 1 756 ? 32.775 79.974 -32.805 1.00 11.43 ? 756 VAL A CG1 1 ATOM 6119 C CG2 . VAL A 1 756 ? 34.199 78.721 -34.540 1.00 13.21 ? 756 VAL A CG2 1 ATOM 6120 N N . SER A 1 757 ? 35.101 81.262 -30.632 1.00 9.51 ? 757 SER A N 1 ATOM 6121 C CA . SER A 1 757 ? 34.959 81.636 -29.241 1.00 9.22 ? 757 SER A CA 1 ATOM 6122 C C . SER A 1 757 ? 33.832 82.607 -29.122 1.00 10.58 ? 757 SER A C 1 ATOM 6123 O O . SER A 1 757 ? 33.712 83.490 -30.001 1.00 12.86 ? 757 SER A O 1 ATOM 6124 C CB . SER A 1 757 ? 36.262 82.328 -28.738 1.00 11.54 ? 757 SER A CB 1 ATOM 6125 O OG . SER A 1 757 ? 37.393 81.452 -28.905 1.00 14.86 ? 757 SER A OG 1 ATOM 6126 N N . VAL A 1 758 ? 33.035 82.543 -28.083 1.00 10.09 ? 758 VAL A N 1 ATOM 6127 C CA . VAL A 1 758 ? 31.907 83.468 -27.927 1.00 10.22 ? 758 VAL A CA 1 ATOM 6128 C C . VAL A 1 758 ? 31.802 83.915 -26.493 1.00 10.83 ? 758 VAL A C 1 ATOM 6129 O O . VAL A 1 758 ? 31.970 83.107 -25.535 1.00 10.82 ? 758 VAL A O 1 ATOM 6130 C CB . VAL A 1 758 ? 30.628 82.819 -28.458 1.00 11.11 ? 758 VAL A CB 1 ATOM 6131 C CG1 . VAL A 1 758 ? 30.317 81.463 -27.770 1.00 12.16 ? 758 VAL A CG1 1 ATOM 6132 C CG2 . VAL A 1 758 ? 29.485 83.769 -28.254 1.00 12.49 ? 758 VAL A CG2 1 ATOM 6133 N N . GLY A 1 759 ? 31.557 85.211 -26.294 1.00 10.72 ? 759 GLY A N 1 ATOM 6134 C CA . GLY A 1 759 ? 31.423 85.771 -24.965 1.00 10.91 ? 759 GLY A CA 1 ATOM 6135 C C . GLY A 1 759 ? 29.992 85.734 -24.507 1.00 13.00 ? 759 GLY A C 1 ATOM 6136 O O . GLY A 1 759 ? 29.145 86.596 -24.835 1.00 13.01 ? 759 GLY A O 1 ATOM 6137 N N . LEU A 1 760 ? 29.622 84.717 -23.771 1.00 12.77 ? 760 LEU A N 1 ATOM 6138 C CA . LEU A 1 760 ? 28.259 84.562 -23.240 1.00 12.12 ? 760 LEU A CA 1 ATOM 6139 C C . LEU A 1 760 ? 28.173 85.057 -21.841 1.00 11.83 ? 760 LEU A C 1 ATOM 6140 O O . LEU A 1 760 ? 29.221 85.247 -21.168 1.00 14.37 ? 760 LEU A O 1 ATOM 6141 C CB . LEU A 1 760 ? 27.889 83.036 -23.235 1.00 13.96 ? 760 LEU A CB 1 ATOM 6142 C CG . LEU A 1 760 ? 28.065 82.335 -24.571 1.00 13.97 ? 760 LEU A CG 1 ATOM 6143 C CD1 . LEU A 1 760 ? 27.783 80.831 -24.383 1.00 16.95 ? 760 LEU A CD1 1 ATOM 6144 C CD2 . LEU A 1 760 ? 27.111 82.907 -25.673 1.00 18.55 ? 760 LEU A CD2 1 ATOM 6145 N N . PRO A 1 761 ? 26.979 85.280 -21.301 1.00 14.47 ? 761 PRO A N 1 ATOM 6146 C CA . PRO A 1 761 ? 26.926 85.738 -19.899 1.00 15.27 ? 761 PRO A CA 1 ATOM 6147 C C . PRO A 1 761 ? 27.492 84.582 -19.019 1.00 15.48 ? 761 PRO A C 1 ATOM 6148 O O . PRO A 1 761 ? 27.050 83.404 -19.105 1.00 17.34 ? 761 PRO A O 1 ATOM 6149 C CB . PRO A 1 761 ? 25.422 85.972 -19.638 1.00 17.18 ? 761 PRO A CB 1 ATOM 6150 C CG . PRO A 1 761 ? 24.870 86.205 -21.012 1.00 17.37 ? 761 PRO A CG 1 ATOM 6151 C CD . PRO A 1 761 ? 25.642 85.294 -21.928 1.00 17.53 ? 761 PRO A CD 1 ATOM 6152 N N . SER A 1 762 ? 28.481 84.959 -18.222 1.00 13.81 ? 762 SER A N 1 ATOM 6153 C CA . SER A 1 762 ? 29.213 84.097 -17.297 1.00 12.88 ? 762 SER A CA 1 ATOM 6154 C C . SER A 1 762 ? 30.152 83.112 -17.946 1.00 11.96 ? 762 SER A C 1 ATOM 6155 O O . SER A 1 762 ? 30.824 82.394 -17.180 1.00 12.48 ? 762 SER A O 1 ATOM 6156 C CB . SER A 1 762 ? 28.290 83.258 -16.409 1.00 16.39 ? 762 SER A CB 1 ATOM 6157 O OG . SER A 1 762 ? 27.393 84.048 -15.677 1.00 19.32 ? 762 SER A OG 1 ATOM 6158 N N . VAL A 1 763 ? 30.218 82.993 -19.255 1.00 11.53 ? 763 VAL A N 1 ATOM 6159 C CA . VAL A 1 763 ? 31.120 82.016 -19.848 1.00 10.45 ? 763 VAL A CA 1 ATOM 6160 C C . VAL A 1 763 ? 31.711 82.448 -21.158 1.00 11.41 ? 763 VAL A C 1 ATOM 6161 O O . VAL A 1 763 ? 30.953 82.805 -22.073 1.00 12.46 ? 763 VAL A O 1 ATOM 6162 C CB . VAL A 1 763 ? 30.374 80.669 -20.133 1.00 14.39 ? 763 VAL A CB 1 ATOM 6163 C CG1 . VAL A 1 763 ? 31.342 79.633 -20.676 1.00 13.15 ? 763 VAL A CG1 1 ATOM 6164 C CG2 . VAL A 1 763 ? 29.661 80.139 -18.935 1.00 15.65 ? 763 VAL A CG2 1 ATOM 6165 N N . VAL A 1 764 ? 33.038 82.440 -21.305 1.00 9.51 ? 764 VAL A N 1 ATOM 6166 C CA . VAL A 1 764 ? 33.608 82.626 -22.631 1.00 9.20 ? 764 VAL A CA 1 ATOM 6167 C C . VAL A 1 764 ? 33.782 81.154 -23.074 1.00 10.38 ? 764 VAL A C 1 ATOM 6168 O O . VAL A 1 764 ? 34.608 80.386 -22.495 1.00 9.74 ? 764 VAL A O 1 ATOM 6169 C CB . VAL A 1 764 ? 34.976 83.368 -22.643 1.00 10.16 ? 764 VAL A CB 1 ATOM 6170 C CG1 . VAL A 1 764 ? 35.539 83.474 -24.096 1.00 12.43 ? 764 VAL A CG1 1 ATOM 6171 C CG2 . VAL A 1 764 ? 34.732 84.765 -22.035 1.00 12.49 ? 764 VAL A CG2 1 ATOM 6172 N N . HIS A 1 765 ? 33.036 80.762 -24.090 1.00 9.19 ? 765 HIS A N 1 ATOM 6173 C CA . HIS A 1 765 ? 32.948 79.361 -24.573 1.00 9.19 ? 765 HIS A CA 1 ATOM 6174 C C . HIS A 1 765 ? 33.792 79.240 -25.821 1.00 10.70 ? 765 HIS A C 1 ATOM 6175 O O . HIS A 1 765 ? 33.617 80.064 -26.760 1.00 10.84 ? 765 HIS A O 1 ATOM 6176 C CB . HIS A 1 765 ? 31.475 79.036 -24.895 1.00 10.12 ? 765 HIS A CB 1 ATOM 6177 C CG . HIS A 1 765 ? 31.261 77.683 -25.460 1.00 9.00 ? 765 HIS A CG 1 ATOM 6178 N ND1 . HIS A 1 765 ? 30.738 77.400 -26.713 1.00 13.99 ? 765 HIS A ND1 1 ATOM 6179 C CD2 . HIS A 1 765 ? 31.472 76.476 -24.874 1.00 7.20 ? 765 HIS A CD2 1 ATOM 6180 C CE1 . HIS A 1 765 ? 30.644 76.081 -26.875 1.00 8.04 ? 765 HIS A CE1 1 ATOM 6181 N NE2 . HIS A 1 765 ? 31.093 75.500 -25.764 1.00 13.67 ? 765 HIS A NE2 1 ATOM 6182 N N A GLN A 1 766 ? 34.679 78.273 -25.921 0.50 9.35 ? 766 GLN A N 1 ATOM 6183 N N B GLN A 1 766 ? 34.679 78.273 -25.921 0.50 9.52 ? 766 GLN A N 1 ATOM 6184 C CA A GLN A 1 766 ? 35.585 78.136 -27.038 0.50 10.20 ? 766 GLN A CA 1 ATOM 6185 C CA B GLN A 1 766 ? 35.585 78.136 -27.038 0.50 10.15 ? 766 GLN A CA 1 ATOM 6186 C C A GLN A 1 766 ? 35.619 76.721 -27.550 0.50 10.14 ? 766 GLN A C 1 ATOM 6187 C C B GLN A 1 766 ? 35.619 76.721 -27.550 0.50 10.33 ? 766 GLN A C 1 ATOM 6188 O O A GLN A 1 766 ? 35.752 75.768 -26.768 0.50 10.83 ? 766 GLN A O 1 ATOM 6189 O O B GLN A 1 766 ? 35.752 75.768 -26.768 0.50 11.05 ? 766 GLN A O 1 ATOM 6190 C CB A GLN A 1 766 ? 37.040 78.528 -26.631 0.50 10.92 ? 766 GLN A CB 1 ATOM 6191 C CB B GLN A 1 766 ? 37.040 78.528 -26.631 0.50 10.30 ? 766 GLN A CB 1 ATOM 6192 C CG A GLN A 1 766 ? 37.165 79.856 -25.865 0.50 13.19 ? 766 GLN A CG 1 ATOM 6193 C CG B GLN A 1 766 ? 38.094 78.349 -27.737 0.50 11.59 ? 766 GLN A CG 1 ATOM 6194 C CD A GLN A 1 766 ? 38.201 79.838 -24.667 0.50 18.39 ? 766 GLN A CD 1 ATOM 6195 C CD B GLN A 1 766 ? 39.537 78.895 -27.375 0.50 16.17 ? 766 GLN A CD 1 ATOM 6196 O OE1 A GLN A 1 766 ? 39.378 79.492 -24.894 0.50 14.43 ? 766 GLN A OE1 1 ATOM 6197 O OE1 B GLN A 1 766 ? 40.303 79.230 -28.300 0.50 16.75 ? 766 GLN A OE1 1 ATOM 6198 N NE2 A GLN A 1 766 ? 37.747 80.200 -23.380 0.50 11.73 ? 766 GLN A NE2 1 ATOM 6199 N NE2 B GLN A 1 766 ? 39.907 78.966 -26.014 0.50 17.99 ? 766 GLN A NE2 1 ATOM 6200 N N . THR A 1 767 ? 35.507 76.564 -28.857 1.00 8.80 ? 767 THR A N 1 ATOM 6201 C CA . THR A 1 767 ? 35.642 75.286 -29.537 1.00 9.63 ? 767 THR A CA 1 ATOM 6202 C C . THR A 1 767 ? 36.891 75.318 -30.373 1.00 9.63 ? 767 THR A C 1 ATOM 6203 O O . THR A 1 767 ? 36.971 76.203 -31.274 1.00 11.72 ? 767 THR A O 1 ATOM 6204 C CB . THR A 1 767 ? 34.428 74.979 -30.411 1.00 10.20 ? 767 THR A CB 1 ATOM 6205 O OG1 . THR A 1 767 ? 33.253 75.070 -29.635 1.00 13.01 ? 767 THR A OG1 1 ATOM 6206 C CG2 . THR A 1 767 ? 34.553 73.589 -31.018 1.00 11.68 ? 767 THR A CG2 1 ATOM 6207 N N . ILE A 1 768 ? 37.888 74.477 -30.126 1.00 9.90 ? 768 ILE A N 1 ATOM 6208 C CA . ILE A 1 768 ? 39.166 74.456 -30.789 1.00 9.71 ? 768 ILE A CA 1 ATOM 6209 C C . ILE A 1 768 ? 39.337 73.214 -31.616 1.00 11.15 ? 768 ILE A C 1 ATOM 6210 O O . ILE A 1 768 ? 39.053 72.099 -31.110 1.00 11.31 ? 768 ILE A O 1 ATOM 6211 C CB . ILE A 1 768 ? 40.279 74.597 -29.746 1.00 10.36 ? 768 ILE A CB 1 ATOM 6212 C CG1 . ILE A 1 768 ? 40.066 75.852 -28.893 1.00 13.16 ? 768 ILE A CG1 1 ATOM 6213 C CG2 . ILE A 1 768 ? 41.612 74.666 -30.444 1.00 13.79 ? 768 ILE A CG2 1 ATOM 6214 C CD1 . ILE A 1 768 ? 40.999 75.847 -27.593 1.00 14.87 ? 768 ILE A CD1 1 ATOM 6215 N N A MET A 1 769 ? 39.817 73.361 -32.830 0.50 11.12 ? 769 MET A N 1 ATOM 6216 N N B MET A 1 769 ? 39.817 73.361 -32.830 0.50 10.89 ? 769 MET A N 1 ATOM 6217 C CA A MET A 1 769 ? 39.960 72.262 -33.798 0.50 11.41 ? 769 MET A CA 1 ATOM 6218 C CA B MET A 1 769 ? 39.960 72.262 -33.798 0.50 10.78 ? 769 MET A CA 1 ATOM 6219 C C A MET A 1 769 ? 41.388 72.139 -34.207 0.50 12.19 ? 769 MET A C 1 ATOM 6220 C C B MET A 1 769 ? 41.388 72.139 -34.207 0.50 11.95 ? 769 MET A C 1 ATOM 6221 O O A MET A 1 769 ? 42.008 73.097 -34.686 0.50 11.92 ? 769 MET A O 1 ATOM 6222 O O B MET A 1 769 ? 42.008 73.097 -34.686 0.50 11.81 ? 769 MET A O 1 ATOM 6223 C CB A MET A 1 769 ? 39.104 72.563 -35.034 0.50 14.29 ? 769 MET A CB 1 ATOM 6224 C CB B MET A 1 769 ? 39.104 72.563 -35.034 0.50 13.06 ? 769 MET A CB 1 ATOM 6225 C CG A MET A 1 769 ? 37.662 72.565 -34.668 0.50 14.96 ? 769 MET A CG 1 ATOM 6226 C CG B MET A 1 769 ? 37.662 72.565 -34.668 0.50 11.03 ? 769 MET A CG 1 ATOM 6227 S SD A MET A 1 769 ? 36.606 73.290 -35.921 0.50 22.20 ? 769 MET A SD 1 ATOM 6228 S SD B MET A 1 769 ? 36.606 73.290 -35.921 0.50 14.83 ? 769 MET A SD 1 ATOM 6229 C CE A MET A 1 769 ? 36.573 75.052 -35.127 0.50 21.85 ? 769 MET A CE 1 ATOM 6230 C CE B MET A 1 769 ? 36.940 71.923 -37.246 0.50 14.54 ? 769 MET A CE 1 ATOM 6231 N N . ARG A 1 770 ? 41.939 70.939 -34.092 1.00 12.27 ? 770 ARG A N 1 ATOM 6232 C CA . ARG A 1 770 ? 43.286 70.664 -34.488 1.00 11.87 ? 770 ARG A CA 1 ATOM 6233 C C . ARG A 1 770 ? 43.399 69.489 -35.436 1.00 13.95 ? 770 ARG A C 1 ATOM 6234 O O . ARG A 1 770 ? 44.520 69.006 -35.665 1.00 18.19 ? 770 ARG A O 1 ATOM 6235 C CB . ARG A 1 770 ? 44.198 70.477 -33.281 1.00 13.05 ? 770 ARG A CB 1 ATOM 6236 C CG . ARG A 1 770 ? 44.264 71.715 -32.406 1.00 16.27 ? 770 ARG A CG 1 ATOM 6237 C CD . ARG A 1 770 ? 45.106 71.449 -31.166 1.00 19.18 ? 770 ARG A CD 1 ATOM 6238 N NE . ARG A 1 770 ? 45.159 72.602 -30.303 1.00 24.89 ? 770 ARG A NE 1 ATOM 6239 C CZ . ARG A 1 770 ? 44.522 72.663 -29.141 1.00 27.15 ? 770 ARG A CZ 1 ATOM 6240 N NH1 . ARG A 1 770 ? 43.783 71.633 -28.739 1.00 30.89 ? 770 ARG A NH1 1 ATOM 6241 N NH2 . ARG A 1 770 ? 44.672 73.724 -28.352 1.00 34.58 ? 770 ARG A NH2 1 ATOM 6242 N N . GLY A 1 771 ? 42.258 69.045 -35.925 1.00 13.95 ? 771 GLY A N 1 ATOM 6243 C CA . GLY A 1 771 ? 42.295 67.967 -36.883 1.00 17.42 ? 771 GLY A CA 1 ATOM 6244 C C . GLY A 1 771 ? 41.662 66.697 -36.413 1.00 19.62 ? 771 GLY A C 1 ATOM 6245 O O . GLY A 1 771 ? 41.485 65.797 -37.246 1.00 20.64 ? 771 GLY A O 1 ATOM 6246 N N . GLY A 1 772 ? 41.326 66.607 -35.120 1.00 16.69 ? 772 GLY A N 1 ATOM 6247 C CA . GLY A 1 772 ? 40.672 65.412 -34.549 1.00 19.18 ? 772 GLY A CA 1 ATOM 6248 C C . GLY A 1 772 ? 39.452 65.903 -33.761 1.00 17.24 ? 772 GLY A C 1 ATOM 6249 O O . GLY A 1 772 ? 38.857 66.940 -34.088 1.00 14.64 ? 772 GLY A O 1 ATOM 6250 N N . ALA A 1 773 ? 39.025 65.166 -32.730 1.00 14.03 ? 773 ALA A N 1 ATOM 6251 C CA . ALA A 1 773 ? 37.912 65.634 -31.910 1.00 12.94 ? 773 ALA A CA 1 ATOM 6252 C C . ALA A 1 773 ? 38.218 67.030 -31.351 1.00 11.79 ? 773 ALA A C 1 ATOM 6253 O O . ALA A 1 773 ? 39.348 67.312 -30.931 1.00 11.39 ? 773 ALA A O 1 ATOM 6254 C CB . ALA A 1 773 ? 37.659 64.695 -30.761 1.00 14.04 ? 773 ALA A CB 1 ATOM 6255 N N . PRO A 1 774 ? 37.234 67.903 -31.341 1.00 10.08 ? 774 PRO A N 1 ATOM 6256 C CA . PRO A 1 774 ? 37.508 69.267 -30.821 1.00 10.35 ? 774 PRO A CA 1 ATOM 6257 C C . PRO A 1 774 ? 37.815 69.293 -29.324 1.00 9.17 ? 774 PRO A C 1 ATOM 6258 O O . PRO A 1 774 ? 37.458 68.359 -28.560 1.00 10.10 ? 774 PRO A O 1 ATOM 6259 C CB . PRO A 1 774 ? 36.188 70.028 -31.088 1.00 12.05 ? 774 PRO A CB 1 ATOM 6260 C CG . PRO A 1 774 ? 35.168 68.983 -31.212 1.00 16.43 ? 774 PRO A CG 1 ATOM 6261 C CD . PRO A 1 774 ? 35.864 67.753 -31.855 1.00 10.84 ? 774 PRO A CD 1 ATOM 6262 N N . GLU A 1 775 ? 38.435 70.370 -28.906 1.00 10.26 ? 775 GLU A N 1 ATOM 6263 C CA . GLU A 1 775 ? 38.689 70.660 -27.520 1.00 9.42 ? 775 GLU A CA 1 ATOM 6264 C C . GLU A 1 775 ? 37.736 71.782 -27.172 1.00 8.99 ? 775 GLU A C 1 ATOM 6265 O O . GLU A 1 775 ? 37.522 72.731 -28.004 1.00 11.63 ? 775 GLU A O 1 ATOM 6266 C CB . GLU A 1 775 ? 40.119 71.114 -27.309 1.00 10.14 ? 775 GLU A CB 1 ATOM 6267 C CG . GLU A 1 775 ? 40.425 71.587 -25.801 1.00 11.90 ? 775 GLU A CG 1 ATOM 6268 C CD . GLU A 1 775 ? 41.856 71.996 -25.547 1.00 18.23 ? 775 GLU A CD 1 ATOM 6269 O OE1 . GLU A 1 775 ? 42.722 71.856 -26.421 1.00 27.56 ? 775 GLU A OE1 1 ATOM 6270 O OE2 . GLU A 1 775 ? 42.149 72.496 -24.434 1.00 17.02 ? 775 GLU A OE2 1 ATOM 6271 N N . ILE A 1 776 ? 37.068 71.727 -26.061 1.00 8.68 ? 776 ILE A N 1 ATOM 6272 C CA . ILE A 1 776 ? 36.186 72.779 -25.591 1.00 9.63 ? 776 ILE A CA 1 ATOM 6273 C C . ILE A 1 776 ? 36.833 73.422 -24.381 1.00 9.40 ? 776 ILE A C 1 ATOM 6274 O O . ILE A 1 776 ? 37.324 72.692 -23.475 1.00 9.52 ? 776 ILE A O 1 ATOM 6275 C CB . ILE A 1 776 ? 34.788 72.229 -25.160 1.00 10.04 ? 776 ILE A CB 1 ATOM 6276 C CG1 . ILE A 1 776 ? 34.176 71.310 -26.241 1.00 14.16 ? 776 ILE A CG1 1 ATOM 6277 C CG2 . ILE A 1 776 ? 33.907 73.384 -24.744 1.00 12.10 ? 776 ILE A CG2 1 ATOM 6278 C CD1 . ILE A 1 776 ? 34.073 71.864 -27.680 1.00 16.16 ? 776 ILE A CD1 1 ATOM 6279 N N . ARG A 1 777 ? 36.884 74.739 -24.325 1.00 9.41 ? 777 ARG A N 1 ATOM 6280 C CA . ARG A 1 777 ? 37.351 75.447 -23.110 1.00 9.75 ? 777 ARG A CA 1 ATOM 6281 C C . ARG A 1 777 ? 36.288 76.432 -22.662 1.00 9.64 ? 777 ARG A C 1 ATOM 6282 O O . ARG A 1 777 ? 35.774 77.219 -23.520 1.00 10.63 ? 777 ARG A O 1 ATOM 6283 C CB . ARG A 1 777 ? 38.674 76.197 -23.339 1.00 10.74 ? 777 ARG A CB 1 ATOM 6284 C CG . ARG A 1 777 ? 39.811 75.310 -23.730 1.00 10.19 ? 777 ARG A CG 1 ATOM 6285 C CD . ARG A 1 777 ? 41.100 76.091 -23.870 1.00 11.54 ? 777 ARG A CD 1 ATOM 6286 N NE . ARG A 1 777 ? 42.166 75.214 -24.344 1.00 13.27 ? 777 ARG A NE 1 ATOM 6287 C CZ . ARG A 1 777 ? 43.361 75.648 -24.766 1.00 14.95 ? 777 ARG A CZ 1 ATOM 6288 N NH1 . ARG A 1 777 ? 43.621 76.978 -24.702 1.00 19.28 ? 777 ARG A NH1 1 ATOM 6289 N NH2 . ARG A 1 777 ? 44.259 74.835 -25.343 1.00 16.65 ? 777 ARG A NH2 1 ATOM 6290 N N . ASN A 1 778 ? 35.900 76.432 -21.412 1.00 8.75 ? 778 ASN A N 1 ATOM 6291 C CA . ASN A 1 778 ? 34.989 77.405 -20.896 1.00 8.74 ? 778 ASN A CA 1 ATOM 6292 C C . ASN A 1 778 ? 35.680 78.234 -19.822 1.00 8.16 ? 778 ASN A C 1 ATOM 6293 O O . ASN A 1 778 ? 36.124 77.671 -18.782 1.00 8.45 ? 778 ASN A O 1 ATOM 6294 C CB . ASN A 1 778 ? 33.767 76.749 -20.217 1.00 10.45 ? 778 ASN A CB 1 ATOM 6295 C CG . ASN A 1 778 ? 32.819 76.078 -21.191 1.00 10.24 ? 778 ASN A CG 1 ATOM 6296 O OD1 . ASN A 1 778 ? 32.758 76.457 -22.370 1.00 10.96 ? 778 ASN A OD1 1 ATOM 6297 N ND2 . ASN A 1 778 ? 32.050 75.117 -20.675 1.00 10.69 ? 778 ASN A ND2 1 ATOM 6298 N N . LEU A 1 779 ? 35.717 79.563 -20.008 1.00 8.60 ? 779 LEU A N 1 ATOM 6299 C CA . LEU A 1 779 ? 36.244 80.441 -18.930 1.00 8.62 ? 779 LEU A CA 1 ATOM 6300 C C . LEU A 1 779 ? 34.998 80.847 -18.180 1.00 8.28 ? 779 LEU A C 1 ATOM 6301 O O . LEU A 1 779 ? 34.155 81.659 -18.700 1.00 10.21 ? 779 LEU A O 1 ATOM 6302 C CB . LEU A 1 779 ? 37.017 81.632 -19.540 1.00 10.76 ? 779 LEU A CB 1 ATOM 6303 C CG . LEU A 1 779 ? 37.531 82.613 -18.471 1.00 13.14 ? 779 LEU A CG 1 ATOM 6304 C CD1 . LEU A 1 779 ? 38.598 82.019 -17.612 1.00 16.88 ? 779 LEU A CD1 1 ATOM 6305 C CD2 . LEU A 1 779 ? 38.036 83.865 -19.302 1.00 20.46 ? 779 LEU A CD2 1 ATOM 6306 N N . VAL A 1 780 ? 34.826 80.252 -17.000 1.00 9.21 ? 780 VAL A N 1 ATOM 6307 C CA . VAL A 1 780 ? 33.587 80.441 -16.262 1.00 10.30 ? 780 VAL A CA 1 ATOM 6308 C C . VAL A 1 780 ? 33.711 81.439 -15.134 1.00 9.01 ? 780 VAL A C 1 ATOM 6309 O O . VAL A 1 780 ? 34.502 81.225 -14.229 1.00 10.91 ? 780 VAL A O 1 ATOM 6310 C CB . VAL A 1 780 ? 33.080 79.046 -15.688 1.00 9.44 ? 780 VAL A CB 1 ATOM 6311 C CG1 . VAL A 1 780 ? 31.739 79.204 -14.958 1.00 11.55 ? 780 VAL A CG1 1 ATOM 6312 C CG2 . VAL A 1 780 ? 32.969 78.034 -16.827 1.00 10.12 ? 780 VAL A CG2 1 ATOM 6313 N N . ASP A 1 781 ? 32.953 82.533 -15.222 1.00 10.03 ? 781 ASP A N 1 ATOM 6314 C CA . ASP A 1 781 ? 32.932 83.547 -14.156 1.00 11.33 ? 781 ASP A CA 1 ATOM 6315 C C . ASP A 1 781 ? 31.501 83.859 -13.794 1.00 11.83 ? 781 ASP A C 1 ATOM 6316 O O . ASP A 1 781 ? 30.817 84.706 -14.470 1.00 12.18 ? 781 ASP A O 1 ATOM 6317 C CB . ASP A 1 781 ? 33.634 84.814 -14.634 1.00 14.61 ? 781 ASP A CB 1 ATOM 6318 C CG . ASP A 1 781 ? 33.687 85.864 -13.553 1.00 16.24 ? 781 ASP A CG 1 ATOM 6319 O OD1 . ASP A 1 781 ? 34.211 86.965 -13.877 1.00 21.68 ? 781 ASP A OD1 1 ATOM 6320 O OD2 . ASP A 1 781 ? 33.245 85.662 -12.399 1.00 15.44 ? 781 ASP A OD2 1 ATOM 6321 N N . ILE A 1 782 ? 30.976 83.158 -12.807 1.00 11.22 ? 782 ILE A N 1 ATOM 6322 C CA . ILE A 1 782 ? 29.570 83.288 -12.403 1.00 12.62 ? 782 ILE A CA 1 ATOM 6323 C C . ILE A 1 782 ? 29.327 84.646 -11.756 1.00 15.87 ? 782 ILE A C 1 ATOM 6324 O O . ILE A 1 782 ? 28.153 85.055 -11.545 1.00 17.90 ? 782 ILE A O 1 ATOM 6325 C CB . ILE A 1 782 ? 29.230 82.070 -11.529 1.00 13.70 ? 782 ILE A CB 1 ATOM 6326 C CG1 . ILE A 1 782 ? 27.731 81.918 -11.338 1.00 15.99 ? 782 ILE A CG1 1 ATOM 6327 C CG2 . ILE A 1 782 ? 29.975 82.224 -10.151 1.00 16.19 ? 782 ILE A CG2 1 ATOM 6328 C CD1 . ILE A 1 782 ? 27.453 80.458 -10.841 1.00 15.90 ? 782 ILE A CD1 1 ATOM 6329 N N . GLY A 1 783 ? 30.388 85.379 -11.424 1.00 15.99 ? 783 GLY A N 1 ATOM 6330 C CA . GLY A 1 783 ? 30.186 86.777 -10.987 1.00 16.11 ? 783 GLY A CA 1 ATOM 6331 C C . GLY A 1 783 ? 29.361 86.912 -9.745 1.00 17.56 ? 783 GLY A C 1 ATOM 6332 O O . GLY A 1 783 ? 29.591 86.174 -8.762 1.00 21.24 ? 783 GLY A O 1 ATOM 6333 N N . SER A 1 784 ? 28.369 87.791 -9.769 1.00 22.03 ? 784 SER A N 1 ATOM 6334 C CA . SER A 1 784 ? 27.553 87.948 -8.571 1.00 22.52 ? 784 SER A CA 1 ATOM 6335 C C . SER A 1 784 ? 26.163 87.318 -8.717 1.00 23.03 ? 784 SER A C 1 ATOM 6336 O O . SER A 1 784 ? 25.203 87.729 -8.011 1.00 23.27 ? 784 SER A O 1 ATOM 6337 C CB . SER A 1 784 ? 27.413 89.431 -8.204 1.00 26.71 ? 784 SER A CB 1 ATOM 6338 O OG . SER A 1 784 ? 26.708 90.120 -9.218 1.00 34.16 ? 784 SER A OG 1 ATOM 6339 N N . LEU A 1 785 ? 26.022 86.337 -9.606 1.00 21.18 ? 785 LEU A N 1 ATOM 6340 C CA . LEU A 1 785 ? 24.714 85.704 -9.793 1.00 19.81 ? 785 LEU A CA 1 ATOM 6341 C C . LEU A 1 785 ? 24.370 84.757 -8.633 1.00 23.41 ? 785 LEU A C 1 ATOM 6342 O O . LEU A 1 785 ? 24.635 83.508 -8.675 1.00 22.72 ? 785 LEU A O 1 ATOM 6343 C CB . LEU A 1 785 ? 24.693 84.932 -11.118 1.00 19.19 ? 785 LEU A CB 1 ATOM 6344 C CG . LEU A 1 785 ? 24.932 85.727 -12.420 1.00 20.09 ? 785 LEU A CG 1 ATOM 6345 C CD1 . LEU A 1 785 ? 24.950 84.826 -13.593 1.00 24.88 ? 785 LEU A CD1 1 ATOM 6346 C CD2 . LEU A 1 785 ? 23.841 86.794 -12.587 1.00 22.30 ? 785 LEU A CD2 1 ATOM 6347 N N . ASP A 1 786 ? 23.700 85.279 -7.612 1.00 23.00 ? 786 ASP A N 1 ATOM 6348 C CA . ASP A 1 786 ? 23.398 84.434 -6.467 1.00 21.58 ? 786 ASP A CA 1 ATOM 6349 C C . ASP A 1 786 ? 22.311 83.386 -6.796 1.00 14.57 ? 786 ASP A C 1 ATOM 6350 O O . ASP A 1 786 ? 21.481 83.518 -7.694 1.00 18.06 ? 786 ASP A O 1 ATOM 6351 C CB . ASP A 1 786 ? 22.922 85.248 -5.245 1.00 24.82 ? 786 ASP A CB 1 ATOM 6352 C CG . ASP A 1 786 ? 24.054 85.918 -4.458 1.00 28.96 ? 786 ASP A CG 1 ATOM 6353 O OD1 . ASP A 1 786 ? 23.751 86.257 -3.296 1.00 32.84 ? 786 ASP A OD1 1 ATOM 6354 O OD2 . ASP A 1 786 ? 25.205 86.125 -4.945 1.00 27.31 ? 786 ASP A OD2 1 ATOM 6355 N N . ASN A 1 787 ? 22.455 82.297 -6.077 1.00 15.96 ? 787 ASN A N 1 ATOM 6356 C CA . ASN A 1 787 ? 21.542 81.169 -6.189 1.00 13.72 ? 787 ASN A CA 1 ATOM 6357 C C . ASN A 1 787 ? 21.354 80.690 -7.592 1.00 14.97 ? 787 ASN A C 1 ATOM 6358 O O . ASN A 1 787 ? 20.250 80.487 -8.084 1.00 15.43 ? 787 ASN A O 1 ATOM 6359 C CB . ASN A 1 787 ? 20.206 81.518 -5.488 1.00 13.57 ? 787 ASN A CB 1 ATOM 6360 C CG . ASN A 1 787 ? 20.387 81.665 -4.001 1.00 20.83 ? 787 ASN A CG 1 ATOM 6361 O OD1 . ASN A 1 787 ? 21.159 80.922 -3.373 1.00 20.94 ? 787 ASN A OD1 1 ATOM 6362 N ND2 . ASN A 1 787 ? 19.657 82.619 -3.403 1.00 28.51 ? 787 ASN A ND2 1 ATOM 6363 N N . THR A 1 788 ? 22.470 80.460 -8.249 1.00 12.14 ? 788 THR A N 1 ATOM 6364 C CA . THR A 1 788 ? 22.474 80.044 -9.636 1.00 13.01 ? 788 THR A CA 1 ATOM 6365 C C . THR A 1 788 ? 23.507 78.914 -9.856 1.00 11.18 ? 788 THR A C 1 ATOM 6366 O O . THR A 1 788 ? 24.614 79.012 -9.286 1.00 11.87 ? 788 THR A O 1 ATOM 6367 C CB . THR A 1 788 ? 22.940 81.241 -10.555 1.00 15.02 ? 788 THR A CB 1 ATOM 6368 O OG1 . THR A 1 788 ? 21.970 82.319 -10.422 1.00 16.64 ? 788 THR A OG1 1 ATOM 6369 C CG2 . THR A 1 788 ? 22.948 80.829 -12.022 1.00 17.79 ? 788 THR A CG2 1 ATOM 6370 N N . GLU A 1 789 ? 23.146 77.913 -10.637 1.00 10.24 ? 789 GLU A N 1 ATOM 6371 C CA . GLU A 1 789 ? 24.110 76.874 -11.029 1.00 9.30 ? 789 GLU A CA 1 ATOM 6372 C C . GLU A 1 789 ? 24.083 76.898 -12.543 1.00 9.56 ? 789 GLU A C 1 ATOM 6373 O O . GLU A 1 789 ? 23.000 76.807 -13.179 1.00 12.77 ? 789 GLU A O 1 ATOM 6374 C CB . GLU A 1 789 ? 23.719 75.477 -10.474 1.00 9.75 ? 789 GLU A CB 1 ATOM 6375 C CG . GLU A 1 789 ? 23.302 75.511 -9.057 1.00 10.93 ? 789 GLU A CG 1 ATOM 6376 C CD . GLU A 1 789 ? 23.500 74.227 -8.267 1.00 10.50 ? 789 GLU A CD 1 ATOM 6377 O OE1 . GLU A 1 789 ? 24.342 73.377 -8.762 1.00 11.46 ? 789 GLU A OE1 1 ATOM 6378 O OE2 . GLU A 1 789 ? 22.876 74.059 -7.215 1.00 11.37 ? 789 GLU A OE2 1 ATOM 6379 N N . ILE A 1 790 ? 25.222 77.040 -13.197 1.00 8.54 ? 790 ILE A N 1 ATOM 6380 C CA . ILE A 1 790 ? 25.331 77.093 -14.635 1.00 10.16 ? 790 ILE A CA 1 ATOM 6381 C C . ILE A 1 790 ? 25.688 75.728 -15.177 1.00 9.73 ? 790 ILE A C 1 ATOM 6382 O O . ILE A 1 790 ? 26.686 75.125 -14.743 1.00 10.28 ? 790 ILE A O 1 ATOM 6383 C CB . ILE A 1 790 ? 26.425 78.099 -15.103 1.00 11.44 ? 790 ILE A CB 1 ATOM 6384 C CG1 . ILE A 1 790 ? 26.005 79.522 -14.692 1.00 15.96 ? 790 ILE A CG1 1 ATOM 6385 C CG2 . ILE A 1 790 ? 26.627 78.036 -16.608 1.00 13.03 ? 790 ILE A CG2 1 ATOM 6386 C CD1 . ILE A 1 790 ? 27.204 80.495 -14.783 1.00 23.12 ? 790 ILE A CD1 1 ATOM 6387 N N . VAL A 1 791 ? 24.896 75.208 -16.093 1.00 10.61 ? 791 VAL A N 1 ATOM 6388 C CA . VAL A 1 791 ? 25.119 73.917 -16.723 1.00 9.99 ? 791 VAL A CA 1 ATOM 6389 C C . VAL A 1 791 ? 25.367 74.018 -18.186 1.00 10.29 ? 791 VAL A C 1 ATOM 6390 O O . VAL A 1 791 ? 24.776 74.907 -18.897 1.00 10.40 ? 791 VAL A O 1 ATOM 6391 C CB . VAL A 1 791 ? 23.908 72.970 -16.422 1.00 10.82 ? 791 VAL A CB 1 ATOM 6392 C CG1 . VAL A 1 791 ? 22.640 73.457 -17.220 1.00 13.98 ? 791 VAL A CG1 1 ATOM 6393 C CG2 . VAL A 1 791 ? 24.246 71.521 -16.769 1.00 12.58 ? 791 VAL A CG2 1 ATOM 6394 N N . MET A 1 792 ? 26.258 73.215 -18.704 1.00 9.22 ? 792 MET A N 1 ATOM 6395 C CA . MET A 1 792 ? 26.541 73.088 -20.128 1.00 8.62 ? 792 MET A CA 1 ATOM 6396 C C . MET A 1 792 ? 25.870 71.786 -20.594 1.00 9.80 ? 792 MET A C 1 ATOM 6397 O O . MET A 1 792 ? 26.208 70.685 -20.094 1.00 10.59 ? 792 MET A O 1 ATOM 6398 C CB . MET A 1 792 ? 28.054 73.057 -20.437 1.00 10.25 ? 792 MET A CB 1 ATOM 6399 C CG . MET A 1 792 ? 28.321 72.892 -21.916 1.00 10.41 ? 792 MET A CG 1 ATOM 6400 S SD . MET A 1 792 ? 30.094 72.950 -22.300 1.00 10.98 ? 792 MET A SD 1 ATOM 6401 C CE . MET A 1 792 ? 30.723 71.453 -21.526 1.00 12.78 ? 792 MET A CE 1 ATOM 6402 N N . ARG A 1 793 ? 24.919 71.856 -21.528 1.00 9.97 ? 793 ARG A N 1 ATOM 6403 C CA . ARG A 1 793 ? 24.220 70.686 -22.052 1.00 9.73 ? 793 ARG A CA 1 ATOM 6404 C C . ARG A 1 793 ? 24.526 70.477 -23.504 1.00 9.71 ? 793 ARG A C 1 ATOM 6405 O O . ARG A 1 793 ? 24.723 71.441 -24.284 1.00 10.61 ? 793 ARG A O 1 ATOM 6406 C CB . ARG A 1 793 ? 22.715 70.931 -21.850 1.00 10.81 ? 793 ARG A CB 1 ATOM 6407 C CG . ARG A 1 793 ? 21.856 69.710 -22.326 1.00 10.92 ? 793 ARG A CG 1 ATOM 6408 C CD . ARG A 1 793 ? 20.337 69.946 -22.050 1.00 12.37 ? 793 ARG A CD 1 ATOM 6409 N NE . ARG A 1 793 ? 20.090 69.995 -20.622 1.00 11.88 ? 793 ARG A NE 1 ATOM 6410 C CZ . ARG A 1 793 ? 19.036 70.558 -20.038 1.00 12.38 ? 793 ARG A CZ 1 ATOM 6411 N NH1 . ARG A 1 793 ? 18.087 71.140 -20.814 1.00 14.66 ? 793 ARG A NH1 1 ATOM 6412 N NH2 . ARG A 1 793 ? 18.909 70.601 -18.741 1.00 12.32 ? 793 ARG A NH2 1 ATOM 6413 N N . LEU A 1 794 ? 24.623 69.222 -23.915 1.00 9.58 ? 794 LEU A N 1 ATOM 6414 C CA . LEU A 1 794 ? 24.728 68.737 -25.310 1.00 10.20 ? 794 LEU A CA 1 ATOM 6415 C C . LEU A 1 794 ? 23.399 68.050 -25.668 1.00 10.75 ? 794 LEU A C 1 ATOM 6416 O O . LEU A 1 794 ? 22.910 67.188 -24.932 1.00 11.22 ? 794 LEU A O 1 ATOM 6417 C CB . LEU A 1 794 ? 25.846 67.720 -25.481 1.00 12.33 ? 794 LEU A CB 1 ATOM 6418 C CG . LEU A 1 794 ? 27.179 68.424 -25.516 1.00 10.81 ? 794 LEU A CG 1 ATOM 6419 C CD1 . LEU A 1 794 ? 28.319 67.466 -25.086 1.00 14.38 ? 794 LEU A CD1 1 ATOM 6420 C CD2 . LEU A 1 794 ? 27.438 68.855 -26.955 1.00 16.29 ? 794 LEU A CD2 1 ATOM 6421 N N . GLU A 1 795 ? 22.809 68.483 -26.794 1.00 12.02 ? 795 GLU A N 1 ATOM 6422 C CA . GLU A 1 795 ? 21.537 67.925 -27.298 1.00 12.41 ? 795 GLU A CA 1 ATOM 6423 C C . GLU A 1 795 ? 21.849 67.231 -28.608 1.00 13.11 ? 795 GLU A C 1 ATOM 6424 O O . GLU A 1 795 ? 22.399 67.803 -29.556 1.00 13.88 ? 795 GLU A O 1 ATOM 6425 C CB . GLU A 1 795 ? 20.481 69.044 -27.493 1.00 14.54 ? 795 GLU A CB 1 ATOM 6426 C CG . GLU A 1 795 ? 20.075 69.728 -26.231 1.00 17.93 ? 795 GLU A CG 1 ATOM 6427 C CD . GLU A 1 795 ? 19.193 71.000 -26.416 1.00 20.38 ? 795 GLU A CD 1 ATOM 6428 O OE1 . GLU A 1 795 ? 19.197 71.607 -27.526 1.00 26.84 ? 795 GLU A OE1 1 ATOM 6429 O OE2 . GLU A 1 795 ? 18.541 71.440 -25.450 1.00 25.66 ? 795 GLU A OE2 1 ATOM 6430 N N . THR A 1 796 ? 21.488 65.931 -28.686 1.00 13.13 ? 796 THR A N 1 ATOM 6431 C CA . THR A 1 796 ? 21.668 65.139 -29.857 1.00 11.87 ? 796 THR A CA 1 ATOM 6432 C C . THR A 1 796 ? 20.359 64.347 -30.125 1.00 11.24 ? 796 THR A C 1 ATOM 6433 O O . THR A 1 796 ? 19.433 64.420 -29.321 1.00 17.26 ? 796 THR A O 1 ATOM 6434 C CB . THR A 1 796 ? 22.863 64.095 -29.734 1.00 11.92 ? 796 THR A CB 1 ATOM 6435 O OG1 . THR A 1 796 ? 22.433 62.933 -28.984 1.00 11.77 ? 796 THR A OG1 1 ATOM 6436 C CG2 . THR A 1 796 ? 24.050 64.746 -29.025 1.00 13.61 ? 796 THR A CG2 1 ATOM 6437 N N A HIS A 1 797 ? 20.383 63.644 -31.210 0.50 12.24 ? 797 HIS A N 1 ATOM 6438 N N B HIS A 1 797 ? 20.363 63.649 -31.216 0.50 19.00 ? 797 HIS A N 1 ATOM 6439 C CA A HIS A 1 797 ? 19.148 62.818 -31.454 0.50 10.17 ? 797 HIS A CA 1 ATOM 6440 C CA B HIS A 1 797 ? 19.182 62.823 -31.446 0.50 22.85 ? 797 HIS A CA 1 ATOM 6441 C C A HIS A 1 797 ? 19.518 61.363 -31.216 0.50 14.10 ? 797 HIS A C 1 ATOM 6442 C C B HIS A 1 797 ? 19.514 61.350 -31.255 0.50 21.50 ? 797 HIS A C 1 ATOM 6443 O O A HIS A 1 797 ? 18.679 60.525 -31.540 0.50 15.81 ? 797 HIS A O 1 ATOM 6444 O O B HIS A 1 797 ? 18.687 60.525 -31.581 0.50 22.02 ? 797 HIS A O 1 ATOM 6445 C CB A HIS A 1 797 ? 18.527 63.179 -32.867 0.50 10.44 ? 797 HIS A CB 1 ATOM 6446 C CB B HIS A 1 797 ? 18.638 63.016 -32.877 0.50 33.53 ? 797 HIS A CB 1 ATOM 6447 C CG A HIS A 1 797 ? 18.068 64.623 -32.967 0.50 4.64 ? 797 HIS A CG 1 ATOM 6448 C CG B HIS A 1 797 ? 18.606 64.492 -33.344 0.50 41.76 ? 797 HIS A CG 1 ATOM 6449 N ND1 A HIS A 1 797 ? 17.761 65.278 -34.156 0.50 7.19 ? 797 HIS A ND1 1 ATOM 6450 N ND1 B HIS A 1 797 ? 19.417 64.972 -34.350 0.50 47.35 ? 797 HIS A ND1 1 ATOM 6451 C CD2 A HIS A 1 797 ? 17.838 65.529 -31.977 0.50 9.46 ? 797 HIS A CD2 1 ATOM 6452 C CD2 B HIS A 1 797 ? 17.864 65.544 -32.924 0.50 46.73 ? 797 HIS A CD2 1 ATOM 6453 C CE1 A HIS A 1 797 ? 17.357 66.498 -33.890 0.50 11.07 ? 797 HIS A CE1 1 ATOM 6454 C CE1 B HIS A 1 797 ? 19.174 66.259 -34.531 0.50 49.53 ? 797 HIS A CE1 1 ATOM 6455 N NE2 A HIS A 1 797 ? 17.387 66.687 -32.580 0.50 12.17 ? 797 HIS A NE2 1 ATOM 6456 N NE2 B HIS A 1 797 ? 18.236 66.630 -33.678 0.50 49.33 ? 797 HIS A NE2 1 ATOM 6457 N N . ILE A 1 798 ? 20.709 61.036 -30.606 1.00 15.96 ? 798 ILE A N 1 ATOM 6458 C CA . ILE A 1 798 ? 21.143 59.654 -30.258 1.00 14.34 ? 798 ILE A CA 1 ATOM 6459 C C . ILE A 1 798 ? 20.041 59.045 -29.376 1.00 12.02 ? 798 ILE A C 1 ATOM 6460 O O . ILE A 1 798 ? 19.545 59.633 -28.457 1.00 14.02 ? 798 ILE A O 1 ATOM 6461 C CB . ILE A 1 798 ? 22.496 59.696 -29.481 1.00 12.94 ? 798 ILE A CB 1 ATOM 6462 C CG1 . ILE A 1 798 ? 23.596 60.174 -30.409 1.00 14.07 ? 798 ILE A CG1 1 ATOM 6463 C CG2 . ILE A 1 798 ? 22.848 58.240 -28.942 1.00 15.45 ? 798 ILE A CG2 1 ATOM 6464 C CD1 . ILE A 1 798 ? 25.004 60.432 -29.660 1.00 14.40 ? 798 ILE A CD1 1 ATOM 6465 N N . ASP A 1 799 ? 19.618 57.814 -29.765 1.00 14.49 ? 799 ASP A N 1 ATOM 6466 C CA . ASP A 1 799 ? 18.545 57.159 -29.057 1.00 12.67 ? 799 ASP A CA 1 ATOM 6467 C C . ASP A 1 799 ? 19.048 56.357 -27.841 1.00 13.41 ? 799 ASP A C 1 ATOM 6468 O O . ASP A 1 799 ? 19.066 55.120 -27.805 1.00 12.98 ? 799 ASP A O 1 ATOM 6469 C CB . ASP A 1 799 ? 17.761 56.247 -30.042 1.00 16.49 ? 799 ASP A CB 1 ATOM 6470 C CG . ASP A 1 799 ? 16.467 55.723 -29.442 1.00 18.53 ? 799 ASP A CG 1 ATOM 6471 O OD1 . ASP A 1 799 ? 16.000 54.714 -30.001 1.00 25.32 ? 799 ASP A OD1 1 ATOM 6472 O OD2 . ASP A 1 799 ? 15.962 56.196 -28.400 1.00 24.44 ? 799 ASP A OD2 1 ATOM 6473 N N . SER A 1 800 ? 19.502 57.130 -26.856 1.00 12.82 ? 800 SER A N 1 ATOM 6474 C CA . SER A 1 800 ? 20.063 56.539 -25.649 1.00 11.73 ? 800 SER A CA 1 ATOM 6475 C C . SER A 1 800 ? 19.018 56.135 -24.659 1.00 12.26 ? 800 SER A C 1 ATOM 6476 O O . SER A 1 800 ? 19.326 55.333 -23.734 1.00 11.99 ? 800 SER A O 1 ATOM 6477 C CB . SER A 1 800 ? 21.052 57.570 -25.001 1.00 12.81 ? 800 SER A CB 1 ATOM 6478 O OG . SER A 1 800 ? 20.445 58.796 -24.709 1.00 11.57 ? 800 SER A OG 1 ATOM 6479 N N . GLY A 1 801 ? 17.787 56.652 -24.733 1.00 11.47 ? 801 GLY A N 1 ATOM 6480 C CA . GLY A 1 801 ? 16.770 56.278 -23.800 1.00 11.91 ? 801 GLY A CA 1 ATOM 6481 C C . GLY A 1 801 ? 17.055 56.804 -22.434 1.00 12.52 ? 801 GLY A C 1 ATOM 6482 O O . GLY A 1 801 ? 17.148 58.014 -22.270 1.00 13.79 ? 801 GLY A O 1 ATOM 6483 N N . ASP A 1 802 ? 17.136 55.906 -21.457 1.00 11.28 ? 802 ASP A N 1 ATOM 6484 C CA . ASP A 1 802 ? 17.431 56.291 -20.095 1.00 10.98 ? 802 ASP A CA 1 ATOM 6485 C C . ASP A 1 802 ? 18.847 55.841 -19.672 1.00 10.52 ? 802 ASP A C 1 ATOM 6486 O O . ASP A 1 802 ? 19.132 55.881 -18.458 1.00 11.79 ? 802 ASP A O 1 ATOM 6487 C CB . ASP A 1 802 ? 16.354 55.671 -19.157 1.00 13.12 ? 802 ASP A CB 1 ATOM 6488 C CG . ASP A 1 802 ? 16.238 54.141 -19.271 1.00 12.35 ? 802 ASP A CG 1 ATOM 6489 O OD1 . ASP A 1 802 ? 15.293 53.644 -18.584 1.00 18.02 ? 802 ASP A OD1 1 ATOM 6490 O OD2 . ASP A 1 802 ? 17.016 53.483 -19.980 1.00 15.73 ? 802 ASP A OD2 1 ATOM 6491 N N . ILE A 1 803 ? 19.685 55.440 -20.591 1.00 8.80 ? 803 ILE A N 1 ATOM 6492 C CA . ILE A 1 803 ? 21.020 54.945 -20.232 1.00 9.42 ? 803 ILE A CA 1 ATOM 6493 C C . ILE A 1 803 ? 22.101 55.983 -20.559 1.00 9.39 ? 803 ILE A C 1 ATOM 6494 O O . ILE A 1 803 ? 22.072 56.661 -21.580 1.00 9.33 ? 803 ILE A O 1 ATOM 6495 C CB . ILE A 1 803 ? 21.318 53.677 -21.039 1.00 9.03 ? 803 ILE A CB 1 ATOM 6496 C CG1 . ILE A 1 803 ? 20.273 52.577 -20.657 1.00 11.31 ? 803 ILE A CG1 1 ATOM 6497 C CG2 . ILE A 1 803 ? 22.736 53.145 -20.793 1.00 11.27 ? 803 ILE A CG2 1 ATOM 6498 C CD1 . ILE A 1 803 ? 20.215 52.279 -19.172 1.00 13.06 ? 803 ILE A CD1 1 ATOM 6499 N N . PHE A 1 804 ? 23.095 56.072 -19.658 1.00 9.59 ? 804 PHE A N 1 ATOM 6500 C CA . PHE A 1 804 ? 24.295 56.876 -19.899 1.00 9.34 ? 804 PHE A CA 1 ATOM 6501 C C . PHE A 1 804 ? 25.426 56.250 -19.078 1.00 8.83 ? 804 PHE A C 1 ATOM 6502 O O . PHE A 1 804 ? 25.174 55.385 -18.267 1.00 10.29 ? 804 PHE A O 1 ATOM 6503 C CB . PHE A 1 804 ? 24.063 58.387 -19.563 1.00 8.33 ? 804 PHE A CB 1 ATOM 6504 C CG . PHE A 1 804 ? 23.652 58.694 -18.138 1.00 8.30 ? 804 PHE A CG 1 ATOM 6505 C CD1 . PHE A 1 804 ? 24.569 59.324 -17.264 1.00 8.23 ? 804 PHE A CD1 1 ATOM 6506 C CD2 . PHE A 1 804 ? 22.372 58.504 -17.667 1.00 9.01 ? 804 PHE A CD2 1 ATOM 6507 C CE1 . PHE A 1 804 ? 24.186 59.727 -16.025 1.00 8.27 ? 804 PHE A CE1 1 ATOM 6508 C CE2 . PHE A 1 804 ? 21.985 58.906 -16.426 1.00 9.64 ? 804 PHE A CE2 1 ATOM 6509 C CZ . PHE A 1 804 ? 22.903 59.548 -15.563 1.00 9.84 ? 804 PHE A CZ 1 ATOM 6510 N N . TYR A 1 805 ? 26.630 56.702 -19.330 1.00 8.53 ? 805 TYR A N 1 ATOM 6511 C CA . TYR A 1 805 ? 27.807 56.129 -18.649 1.00 8.36 ? 805 TYR A CA 1 ATOM 6512 C C . TYR A 1 805 ? 28.633 57.262 -18.074 1.00 7.49 ? 805 TYR A C 1 ATOM 6513 O O . TYR A 1 805 ? 28.786 58.304 -18.748 1.00 9.06 ? 805 TYR A O 1 ATOM 6514 C CB . TYR A 1 805 ? 28.661 55.365 -19.635 1.00 8.42 ? 805 TYR A CB 1 ATOM 6515 C CG . TYR A 1 805 ? 27.996 54.119 -20.209 1.00 8.20 ? 805 TYR A CG 1 ATOM 6516 C CD1 . TYR A 1 805 ? 26.989 54.238 -21.228 1.00 10.73 ? 805 TYR A CD1 1 ATOM 6517 C CD2 . TYR A 1 805 ? 28.312 52.859 -19.717 1.00 9.24 ? 805 TYR A CD2 1 ATOM 6518 C CE1 . TYR A 1 805 ? 26.344 53.103 -21.703 1.00 10.68 ? 805 TYR A CE1 1 ATOM 6519 C CE2 . TYR A 1 805 ? 27.651 51.704 -20.219 1.00 9.56 ? 805 TYR A CE2 1 ATOM 6520 C CZ . TYR A 1 805 ? 26.686 51.887 -21.189 1.00 11.12 ? 805 TYR A CZ 1 ATOM 6521 O OH . TYR A 1 805 ? 26.042 50.758 -21.708 1.00 12.52 ? 805 TYR A OH 1 ATOM 6522 N N . THR A 1 806 ? 29.120 57.062 -16.853 1.00 8.53 ? 806 THR A N 1 ATOM 6523 C CA . THR A 1 806 ? 29.996 58.072 -16.209 1.00 6.94 ? 806 THR A CA 1 ATOM 6524 C C . THR A 1 806 ? 31.174 57.304 -15.634 1.00 8.80 ? 806 THR A C 1 ATOM 6525 O O . THR A 1 806 ? 31.116 56.081 -15.410 1.00 9.18 ? 806 THR A O 1 ATOM 6526 C CB . THR A 1 806 ? 29.274 58.852 -15.133 1.00 8.60 ? 806 THR A CB 1 ATOM 6527 O OG1 . THR A 1 806 ? 28.901 57.960 -14.093 1.00 8.64 ? 806 THR A OG1 1 ATOM 6528 C CG2 . THR A 1 806 ? 28.003 59.528 -15.663 1.00 8.62 ? 806 THR A CG2 1 ATOM 6529 N N . ASP A 1 807 ? 32.306 57.962 -15.430 1.00 7.49 ? 807 ASP A N 1 ATOM 6530 C CA . ASP A 1 807 ? 33.425 57.255 -14.828 1.00 8.80 ? 807 ASP A CA 1 ATOM 6531 C C . ASP A 1 807 ? 33.481 57.329 -13.328 1.00 7.13 ? 807 ASP A C 1 ATOM 6532 O O . ASP A 1 807 ? 32.842 58.143 -12.668 1.00 7.72 ? 807 ASP A O 1 ATOM 6533 C CB . ASP A 1 807 ? 34.743 57.704 -15.434 1.00 10.65 ? 807 ASP A CB 1 ATOM 6534 C CG . ASP A 1 807 ? 35.165 58.998 -14.957 1.00 10.17 ? 807 ASP A CG 1 ATOM 6535 O OD1 . ASP A 1 807 ? 36.341 59.059 -14.433 1.00 12.16 ? 807 ASP A OD1 1 ATOM 6536 O OD2 . ASP A 1 807 ? 34.412 59.993 -15.044 1.00 11.47 ? 807 ASP A OD2 1 ATOM 6537 N N . LEU A 1 808 ? 34.241 56.396 -12.774 1.00 7.30 ? 808 LEU A N 1 ATOM 6538 C CA . LEU A 1 808 ? 34.545 56.361 -11.328 1.00 6.58 ? 808 LEU A CA 1 ATOM 6539 C C . LEU A 1 808 ? 36.038 56.586 -11.162 1.00 6.57 ? 808 LEU A C 1 ATOM 6540 O O . LEU A 1 808 ? 36.848 55.774 -11.618 1.00 7.31 ? 808 LEU A O 1 ATOM 6541 C CB . LEU A 1 808 ? 34.162 55.024 -10.702 1.00 7.94 ? 808 LEU A CB 1 ATOM 6542 C CG . LEU A 1 808 ? 32.621 54.913 -10.589 1.00 8.96 ? 808 LEU A CG 1 ATOM 6543 C CD1 . LEU A 1 808 ? 32.277 53.411 -10.384 1.00 9.37 ? 808 LEU A CD1 1 ATOM 6544 C CD2 . LEU A 1 808 ? 32.035 55.751 -9.439 1.00 10.18 ? 808 LEU A CD2 1 ATOM 6545 N N . ASN A 1 809 ? 36.377 57.754 -10.608 1.00 6.45 ? 809 ASN A N 1 ATOM 6546 C CA . ASN A 1 809 ? 37.793 58.080 -10.263 1.00 6.32 ? 809 ASN A CA 1 ATOM 6547 C C . ASN A 1 809 ? 38.761 57.972 -11.422 1.00 6.84 ? 809 ASN A C 1 ATOM 6548 O O . ASN A 1 809 ? 39.965 57.708 -11.226 1.00 7.34 ? 809 ASN A O 1 ATOM 6549 C CB . ASN A 1 809 ? 38.286 57.165 -9.102 1.00 6.20 ? 809 ASN A CB 1 ATOM 6550 C CG . ASN A 1 809 ? 37.265 57.123 -8.012 1.00 6.34 ? 809 ASN A CG 1 ATOM 6551 O OD1 . ASN A 1 809 ? 37.250 58.048 -7.094 1.00 10.21 ? 809 ASN A OD1 1 ATOM 6552 N ND2 . ASN A 1 809 ? 36.400 56.180 -8.027 1.00 5.01 ? 809 ASN A ND2 1 ATOM 6553 N N . GLY A 1 810 ? 38.319 58.186 -12.673 1.00 6.70 ? 810 GLY A N 1 ATOM 6554 C CA . GLY A 1 810 ? 39.255 58.090 -13.786 1.00 7.78 ? 810 GLY A CA 1 ATOM 6555 C C . GLY A 1 810 ? 39.686 56.674 -14.083 1.00 8.58 ? 810 GLY A C 1 ATOM 6556 O O . GLY A 1 810 ? 40.647 56.469 -14.887 1.00 10.54 ? 810 GLY A O 1 ATOM 6557 N N . LEU A 1 811 ? 39.067 55.681 -13.467 1.00 7.49 ? 811 LEU A N 1 ATOM 6558 C CA . LEU A 1 811 ? 39.519 54.278 -13.578 1.00 8.36 ? 811 LEU A CA 1 ATOM 6559 C C . LEU A 1 811 ? 38.615 53.362 -14.432 1.00 9.48 ? 811 LEU A C 1 ATOM 6560 O O . LEU A 1 811 ? 39.146 52.483 -15.107 1.00 12.38 ? 811 LEU A O 1 ATOM 6561 C CB . LEU A 1 811 ? 39.607 53.683 -12.139 1.00 9.54 ? 811 LEU A CB 1 ATOM 6562 C CG . LEU A 1 811 ? 40.046 52.218 -11.989 1.00 11.06 ? 811 LEU A CG 1 ATOM 6563 C CD1 . LEU A 1 811 ? 41.479 52.061 -12.506 1.00 13.22 ? 811 LEU A CD1 1 ATOM 6564 C CD2 . LEU A 1 811 ? 39.939 51.731 -10.528 1.00 13.08 ? 811 LEU A CD2 1 ATOM 6565 N N . GLN A 1 812 ? 37.309 53.599 -14.424 1.00 7.47 ? 812 GLN A N 1 ATOM 6566 C CA . GLN A 1 812 ? 36.354 52.686 -15.064 1.00 8.08 ? 812 GLN A CA 1 ATOM 6567 C C . GLN A 1 812 ? 35.117 53.456 -15.385 1.00 7.92 ? 812 GLN A C 1 ATOM 6568 O O . GLN A 1 812 ? 34.828 54.492 -14.730 1.00 9.75 ? 812 GLN A O 1 ATOM 6569 C CB . GLN A 1 812 ? 36.008 51.554 -14.057 1.00 9.11 ? 812 GLN A CB 1 ATOM 6570 C CG . GLN A 1 812 ? 35.430 52.071 -12.743 1.00 12.02 ? 812 GLN A CG 1 ATOM 6571 C CD . GLN A 1 812 ? 35.144 50.945 -11.752 1.00 12.60 ? 812 GLN A CD 1 ATOM 6572 O OE1 . GLN A 1 812 ? 34.187 50.199 -11.907 1.00 13.07 ? 812 GLN A OE1 1 ATOM 6573 N NE2 . GLN A 1 812 ? 35.980 50.855 -10.706 1.00 14.03 ? 812 GLN A NE2 1 ATOM 6574 N N . PHE A 1 813 ? 34.340 52.982 -16.360 1.00 8.19 ? 813 PHE A N 1 ATOM 6575 C CA . PHE A 1 813 ? 33.043 53.599 -16.727 1.00 6.99 ? 813 PHE A CA 1 ATOM 6576 C C . PHE A 1 813 ? 31.950 52.699 -16.281 1.00 8.03 ? 813 PHE A C 1 ATOM 6577 O O . PHE A 1 813 ? 31.979 51.463 -16.600 1.00 10.92 ? 813 PHE A O 1 ATOM 6578 C CB . PHE A 1 813 ? 33.008 53.883 -18.220 1.00 7.59 ? 813 PHE A CB 1 ATOM 6579 C CG . PHE A 1 813 ? 33.784 55.112 -18.605 1.00 7.83 ? 813 PHE A CG 1 ATOM 6580 C CD1 . PHE A 1 813 ? 35.156 55.064 -18.695 1.00 8.53 ? 813 PHE A CD1 1 ATOM 6581 C CD2 . PHE A 1 813 ? 33.064 56.326 -18.796 1.00 8.75 ? 813 PHE A CD2 1 ATOM 6582 C CE1 . PHE A 1 813 ? 35.844 56.266 -18.959 1.00 10.27 ? 813 PHE A CE1 1 ATOM 6583 C CE2 . PHE A 1 813 ? 33.736 57.487 -19.070 1.00 10.84 ? 813 PHE A CE2 1 ATOM 6584 C CZ . PHE A 1 813 ? 35.116 57.446 -19.147 1.00 10.07 ? 813 PHE A CZ 1 ATOM 6585 N N . ILE A 1 814 ? 30.982 53.259 -15.603 1.00 7.70 ? 814 ILE A N 1 ATOM 6586 C CA . ILE A 1 814 ? 29.902 52.460 -15.077 1.00 8.11 ? 814 ILE A CA 1 ATOM 6587 C C . ILE A 1 814 ? 28.599 52.894 -15.741 1.00 8.53 ? 814 ILE A C 1 ATOM 6588 O O . ILE A 1 814 ? 28.334 54.091 -16.004 1.00 7.93 ? 814 ILE A O 1 ATOM 6589 C CB . ILE A 1 814 ? 29.874 52.629 -13.527 1.00 7.76 ? 814 ILE A CB 1 ATOM 6590 C CG1 . ILE A 1 814 ? 28.800 51.693 -12.910 1.00 8.81 ? 814 ILE A CG1 1 ATOM 6591 C CG2 . ILE A 1 814 ? 29.587 54.083 -13.098 1.00 8.73 ? 814 ILE A CG2 1 ATOM 6592 C CD1 . ILE A 1 814 ? 28.968 51.527 -11.353 1.00 8.99 ? 814 ILE A CD1 1 ATOM 6593 N N . LYS A 1 815 ? 27.721 51.915 -16.015 1.00 7.76 ? 815 LYS A N 1 ATOM 6594 C CA . LYS A 1 815 ? 26.408 52.211 -16.611 1.00 8.41 ? 815 LYS A CA 1 ATOM 6595 C C . LYS A 1 815 ? 25.494 52.817 -15.576 1.00 8.20 ? 815 LYS A C 1 ATOM 6596 O O . LYS A 1 815 ? 25.359 52.352 -14.441 1.00 8.75 ? 815 LYS A O 1 ATOM 6597 C CB . LYS A 1 815 ? 25.823 50.891 -17.138 1.00 9.57 ? 815 LYS A CB 1 ATOM 6598 C CG . LYS A 1 815 ? 24.493 51.053 -17.942 1.00 10.26 ? 815 LYS A CG 1 ATOM 6599 C CD . LYS A 1 815 ? 24.052 49.617 -18.418 1.00 13.93 ? 815 LYS A CD 1 ATOM 6600 C CE . LYS A 1 815 ? 22.909 49.678 -19.380 1.00 20.27 ? 815 LYS A CE 1 ATOM 6601 N NZ . LYS A 1 815 ? 22.691 48.215 -19.794 1.00 23.34 ? 815 LYS A NZ 1 ATOM 6602 N N . ARG A 1 816 ? 24.824 53.895 -15.988 1.00 8.50 ? 816 ARG A N 1 ATOM 6603 C CA . ARG A 1 816 ? 23.821 54.592 -15.229 1.00 8.14 ? 816 ARG A CA 1 ATOM 6604 C C . ARG A 1 816 ? 22.477 54.458 -15.934 1.00 9.00 ? 816 ARG A C 1 ATOM 6605 O O . ARG A 1 816 ? 22.413 54.424 -17.149 1.00 8.77 ? 816 ARG A O 1 ATOM 6606 C CB . ARG A 1 816 ? 24.118 56.118 -15.135 1.00 9.24 ? 816 ARG A CB 1 ATOM 6607 C CG . ARG A 1 816 ? 25.579 56.482 -14.577 1.00 8.61 ? 816 ARG A CG 1 ATOM 6608 C CD . ARG A 1 816 ? 25.735 55.868 -13.208 1.00 9.38 ? 816 ARG A CD 1 ATOM 6609 N NE . ARG A 1 816 ? 26.954 56.447 -12.582 1.00 8.80 ? 816 ARG A NE 1 ATOM 6610 C CZ . ARG A 1 816 ? 27.345 56.052 -11.373 1.00 8.87 ? 816 ARG A CZ 1 ATOM 6611 N NH1 . ARG A 1 816 ? 26.659 55.109 -10.726 1.00 8.33 ? 816 ARG A NH1 1 ATOM 6612 N NH2 . ARG A 1 816 ? 28.389 56.622 -10.764 1.00 9.22 ? 816 ARG A NH2 1 ATOM 6613 N N . ARG A 1 817 ? 21.449 54.468 -15.103 1.00 8.72 ? 817 ARG A N 1 ATOM 6614 C CA . ARG A 1 817 ? 20.085 54.485 -15.665 1.00 8.64 ? 817 ARG A CA 1 ATOM 6615 C C . ARG A 1 817 ? 19.360 55.627 -14.968 1.00 8.83 ? 817 ARG A C 1 ATOM 6616 O O . ARG A 1 817 ? 19.231 55.671 -13.742 1.00 10.54 ? 817 ARG A O 1 ATOM 6617 C CB . ARG A 1 817 ? 19.356 53.119 -15.453 1.00 10.26 ? 817 ARG A CB 1 ATOM 6618 C CG . ARG A 1 817 ? 17.884 53.174 -15.954 1.00 12.07 ? 817 ARG A CG 1 ATOM 6619 C CD . ARG A 1 817 ? 17.152 51.799 -15.709 1.00 12.94 ? 817 ARG A CD 1 ATOM 6620 N NE . ARG A 1 817 ? 17.744 50.754 -16.506 1.00 13.22 ? 817 ARG A NE 1 ATOM 6621 C CZ . ARG A 1 817 ? 18.483 49.744 -16.095 1.00 14.54 ? 817 ARG A CZ 1 ATOM 6622 N NH1 . ARG A 1 817 ? 18.789 49.597 -14.825 1.00 13.74 ? 817 ARG A NH1 1 ATOM 6623 N NH2 . ARG A 1 817 ? 18.913 48.847 -16.981 1.00 18.05 ? 817 ARG A NH2 1 ATOM 6624 N N . ARG A 1 818 ? 18.904 56.586 -15.813 1.00 9.04 ? 818 ARG A N 1 ATOM 6625 C CA . ARG A 1 818 ? 18.094 57.671 -15.306 1.00 10.99 ? 818 ARG A CA 1 ATOM 6626 C C . ARG A 1 818 ? 16.778 57.083 -14.750 1.00 11.14 ? 818 ARG A C 1 ATOM 6627 O O . ARG A 1 818 ? 16.153 56.269 -15.461 1.00 13.12 ? 818 ARG A O 1 ATOM 6628 C CB . ARG A 1 818 ? 17.764 58.632 -16.491 1.00 10.30 ? 818 ARG A CB 1 ATOM 6629 C CG . ARG A 1 818 ? 17.015 59.876 -16.013 1.00 12.42 ? 818 ARG A CG 1 ATOM 6630 C CD . ARG A 1 818 ? 16.434 60.680 -17.194 1.00 11.88 ? 818 ARG A CD 1 ATOM 6631 N NE . ARG A 1 818 ? 15.137 60.052 -17.514 1.00 17.99 ? 818 ARG A NE 1 ATOM 6632 C CZ . ARG A 1 818 ? 14.810 59.461 -18.681 1.00 18.15 ? 818 ARG A CZ 1 ATOM 6633 N NH1 . ARG A 1 818 ? 15.641 59.381 -19.715 1.00 15.32 ? 818 ARG A NH1 1 ATOM 6634 N NH2 . ARG A 1 818 ? 13.583 58.911 -18.784 1.00 18.97 ? 818 ARG A NH2 1 ATOM 6635 N N . LEU A 1 819 ? 16.387 57.488 -13.562 1.00 11.43 ? 819 LEU A N 1 ATOM 6636 C CA . LEU A 1 819 ? 15.146 56.959 -12.905 1.00 12.71 ? 819 LEU A CA 1 ATOM 6637 C C . LEU A 1 819 ? 14.191 58.107 -12.625 1.00 11.05 ? 819 LEU A C 1 ATOM 6638 O O . LEU A 1 819 ? 14.436 58.963 -11.799 1.00 12.02 ? 819 LEU A O 1 ATOM 6639 C CB . LEU A 1 819 ? 15.485 56.255 -11.586 1.00 12.50 ? 819 LEU A CB 1 ATOM 6640 C CG . LEU A 1 819 ? 16.450 55.032 -11.725 1.00 13.14 ? 819 LEU A CG 1 ATOM 6641 C CD1 . LEU A 1 819 ? 16.930 54.552 -10.321 1.00 15.80 ? 819 LEU A CD1 1 ATOM 6642 C CD2 . LEU A 1 819 ? 15.818 53.884 -12.505 1.00 14.46 ? 819 LEU A CD2 1 ATOM 6643 N N . ASP A 1 820 ? 13.073 58.064 -13.354 1.00 14.07 ? 820 ASP A N 1 ATOM 6644 C CA . ASP A 1 820 ? 12.108 59.126 -13.163 1.00 14.71 ? 820 ASP A CA 1 ATOM 6645 C C . ASP A 1 820 ? 11.369 58.971 -11.836 1.00 12.80 ? 820 ASP A C 1 ATOM 6646 O O . ASP A 1 820 ? 10.755 59.932 -11.359 1.00 15.49 ? 820 ASP A O 1 ATOM 6647 C CB . ASP A 1 820 ? 11.160 59.213 -14.374 1.00 17.21 ? 820 ASP A CB 1 ATOM 6648 C CG . ASP A 1 820 ? 11.905 59.542 -15.662 1.00 21.95 ? 820 ASP A CG 1 ATOM 6649 O OD1 . ASP A 1 820 ? 12.986 60.200 -15.636 1.00 20.80 ? 820 ASP A OD1 1 ATOM 6650 O OD2 . ASP A 1 820 ? 11.414 59.157 -16.728 1.00 24.33 ? 820 ASP A OD2 1 ATOM 6651 N N . LYS A 1 821 ? 11.561 57.832 -11.147 1.00 13.38 ? 821 LYS A N 1 ATOM 6652 C CA . LYS A 1 821 ? 10.947 57.691 -9.827 1.00 13.84 ? 821 LYS A CA 1 ATOM 6653 C C . LYS A 1 821 ? 11.789 58.438 -8.763 1.00 15.93 ? 821 LYS A C 1 ATOM 6654 O O . LYS A 1 821 ? 11.329 58.604 -7.636 1.00 16.90 ? 821 LYS A O 1 ATOM 6655 C CB . LYS A 1 821 ? 10.814 56.203 -9.444 1.00 12.47 ? 821 LYS A CB 1 ATOM 6656 C CG . LYS A 1 821 ? 12.153 55.496 -9.173 1.00 13.56 ? 821 LYS A CG 1 ATOM 6657 C CD . LYS A 1 821 ? 11.972 54.013 -9.019 1.00 13.53 ? 821 LYS A CD 1 ATOM 6658 C CE . LYS A 1 821 ? 13.334 53.303 -8.986 1.00 15.95 ? 821 LYS A CE 1 ATOM 6659 N NZ . LYS A 1 821 ? 13.242 51.821 -9.187 1.00 16.00 ? 821 LYS A NZ 1 ATOM 6660 N N . LEU A 1 822 ? 12.987 58.932 -9.168 1.00 13.50 ? 822 LEU A N 1 ATOM 6661 C CA . LEU A 1 822 ? 13.815 59.742 -8.221 1.00 12.02 ? 822 LEU A CA 1 ATOM 6662 C C . LEU A 1 822 ? 13.855 61.183 -8.755 1.00 13.59 ? 822 LEU A C 1 ATOM 6663 O O . LEU A 1 822 ? 13.679 61.411 -9.949 1.00 14.33 ? 822 LEU A O 1 ATOM 6664 C CB . LEU A 1 822 ? 15.241 59.213 -8.192 1.00 13.81 ? 822 LEU A CB 1 ATOM 6665 C CG . LEU A 1 822 ? 15.395 57.746 -7.719 1.00 14.88 ? 822 LEU A CG 1 ATOM 6666 C CD1 . LEU A 1 822 ? 16.868 57.379 -7.721 1.00 17.77 ? 822 LEU A CD1 1 ATOM 6667 C CD2 . LEU A 1 822 ? 14.708 57.496 -6.399 1.00 15.15 ? 822 LEU A CD2 1 ATOM 6668 N N . PRO A 1 823 ? 14.077 62.138 -7.870 1.00 12.67 ? 823 PRO A N 1 ATOM 6669 C CA . PRO A 1 823 ? 14.138 63.551 -8.280 1.00 12.13 ? 823 PRO A CA 1 ATOM 6670 C C . PRO A 1 823 ? 15.354 63.846 -9.129 1.00 13.09 ? 823 PRO A C 1 ATOM 6671 O O . PRO A 1 823 ? 16.348 63.064 -9.184 1.00 11.80 ? 823 PRO A O 1 ATOM 6672 C CB . PRO A 1 823 ? 14.104 64.318 -6.961 1.00 13.45 ? 823 PRO A CB 1 ATOM 6673 C CG . PRO A 1 823 ? 14.762 63.409 -5.983 1.00 16.39 ? 823 PRO A CG 1 ATOM 6674 C CD . PRO A 1 823 ? 14.252 61.984 -6.412 1.00 13.58 ? 823 PRO A CD 1 ATOM 6675 N N . LEU A 1 824 ? 15.307 64.967 -9.848 1.00 12.65 ? 824 LEU A N 1 ATOM 6676 C CA . LEU A 1 824 ? 16.359 65.350 -10.746 1.00 12.92 ? 824 LEU A CA 1 ATOM 6677 C C . LEU A 1 824 ? 17.787 65.227 -10.112 1.00 10.94 ? 824 LEU A C 1 ATOM 6678 O O . LEU A 1 824 ? 18.694 64.660 -10.757 1.00 11.43 ? 824 LEU A O 1 ATOM 6679 C CB . LEU A 1 824 ? 16.067 66.806 -11.217 1.00 12.42 ? 824 LEU A CB 1 ATOM 6680 C CG . LEU A 1 824 ? 16.854 67.405 -12.345 1.00 12.17 ? 824 LEU A CG 1 ATOM 6681 C CD1 . LEU A 1 824 ? 16.068 68.665 -12.848 1.00 13.43 ? 824 LEU A CD1 1 ATOM 6682 C CD2 . LEU A 1 824 ? 18.306 67.830 -11.902 1.00 12.51 ? 824 LEU A CD2 1 ATOM 6683 N N . GLN A 1 825 ? 17.948 65.747 -8.905 1.00 10.03 ? 825 GLN A N 1 ATOM 6684 C CA . GLN A 1 825 ? 19.276 65.748 -8.269 1.00 10.04 ? 825 GLN A CA 1 ATOM 6685 C C . GLN A 1 825 ? 19.797 64.375 -7.973 1.00 11.27 ? 825 GLN A C 1 ATOM 6686 O O . GLN A 1 825 ? 21.050 64.220 -7.823 1.00 10.59 ? 825 GLN A O 1 ATOM 6687 C CB . GLN A 1 825 ? 19.268 66.640 -7.040 1.00 11.13 ? 825 GLN A CB 1 ATOM 6688 C CG . GLN A 1 825 ? 18.317 66.118 -5.908 1.00 9.68 ? 825 GLN A CG 1 ATOM 6689 C CD . GLN A 1 825 ? 16.852 66.624 -5.995 1.00 12.64 ? 825 GLN A CD 1 ATOM 6690 O OE1 . GLN A 1 825 ? 16.403 67.102 -7.059 1.00 12.79 ? 825 GLN A OE1 1 ATOM 6691 N NE2 . GLN A 1 825 ? 16.121 66.504 -4.865 1.00 11.56 ? 825 GLN A NE2 1 ATOM 6692 N N . ALA A 1 826 ? 18.926 63.348 -7.869 1.00 10.09 ? 826 ALA A N 1 ATOM 6693 C CA . ALA A 1 826 ? 19.384 61.964 -7.625 1.00 9.72 ? 826 ALA A CA 1 ATOM 6694 C C . ALA A 1 826 ? 19.959 61.403 -8.894 1.00 9.32 ? 826 ALA A C 1 ATOM 6695 O O . ALA A 1 826 ? 20.718 60.404 -8.868 1.00 11.22 ? 826 ALA A O 1 ATOM 6696 C CB . ALA A 1 826 ? 18.169 61.098 -7.168 1.00 10.66 ? 826 ALA A CB 1 ATOM 6697 N N . ASN A 1 827 ? 19.622 61.979 -10.060 1.00 9.43 ? 827 ASN A N 1 ATOM 6698 C CA . ASN A 1 827 ? 20.123 61.489 -11.356 1.00 9.20 ? 827 ASN A CA 1 ATOM 6699 C C . ASN A 1 827 ? 21.447 62.112 -11.796 1.00 7.97 ? 827 ASN A C 1 ATOM 6700 O O . ASN A 1 827 ? 21.944 61.801 -12.843 1.00 9.82 ? 827 ASN A O 1 ATOM 6701 C CB . ASN A 1 827 ? 19.006 61.611 -12.433 1.00 10.36 ? 827 ASN A CB 1 ATOM 6702 C CG . ASN A 1 827 ? 17.897 60.590 -12.173 1.00 11.70 ? 827 ASN A CG 1 ATOM 6703 O OD1 . ASN A 1 827 ? 18.112 59.403 -12.270 1.00 12.28 ? 827 ASN A OD1 1 ATOM 6704 N ND2 . ASN A 1 827 ? 16.706 61.072 -11.805 1.00 15.12 ? 827 ASN A ND2 1 ATOM 6705 N N . TYR A 1 828 ? 21.927 63.000 -10.926 1.00 9.44 ? 828 TYR A N 1 ATOM 6706 C CA . TYR A 1 828 ? 23.259 63.593 -11.119 1.00 8.60 ? 828 TYR A CA 1 ATOM 6707 C C . TYR A 1 828 ? 24.323 62.653 -10.466 1.00 7.76 ? 828 TYR A C 1 ATOM 6708 O O . TYR A 1 828 ? 24.082 62.101 -9.381 1.00 9.66 ? 828 TYR A O 1 ATOM 6709 C CB . TYR A 1 828 ? 23.368 64.975 -10.426 1.00 8.06 ? 828 TYR A CB 1 ATOM 6710 C CG . TYR A 1 828 ? 23.317 66.099 -11.396 1.00 8.90 ? 828 TYR A CG 1 ATOM 6711 C CD1 . TYR A 1 828 ? 22.273 66.306 -12.271 1.00 9.56 ? 828 TYR A CD1 1 ATOM 6712 C CD2 . TYR A 1 828 ? 24.390 66.960 -11.483 1.00 9.62 ? 828 TYR A CD2 1 ATOM 6713 C CE1 . TYR A 1 828 ? 22.305 67.342 -13.214 1.00 11.16 ? 828 TYR A CE1 1 ATOM 6714 C CE2 . TYR A 1 828 ? 24.445 67.982 -12.407 1.00 11.67 ? 828 TYR A CE2 1 ATOM 6715 C CZ . TYR A 1 828 ? 23.411 68.165 -13.270 1.00 9.10 ? 828 TYR A CZ 1 ATOM 6716 O OH . TYR A 1 828 ? 23.540 69.157 -14.231 1.00 11.90 ? 828 TYR A OH 1 ATOM 6717 N N . TYR A 1 829 ? 25.431 62.451 -11.180 1.00 7.86 ? 829 TYR A N 1 ATOM 6718 C CA . TYR A 1 829 ? 26.542 61.609 -10.746 1.00 8.19 ? 829 TYR A CA 1 ATOM 6719 C C . TYR A 1 829 ? 27.844 62.346 -10.923 1.00 8.60 ? 829 TYR A C 1 ATOM 6720 O O . TYR A 1 829 ? 27.948 63.338 -11.625 1.00 8.45 ? 829 TYR A O 1 ATOM 6721 C CB . TYR A 1 829 ? 26.572 60.328 -11.621 1.00 8.52 ? 829 TYR A CB 1 ATOM 6722 C CG . TYR A 1 829 ? 25.388 59.414 -11.363 1.00 8.80 ? 829 TYR A CG 1 ATOM 6723 C CD1 . TYR A 1 829 ? 24.224 59.478 -12.154 1.00 9.20 ? 829 TYR A CD1 1 ATOM 6724 C CD2 . TYR A 1 829 ? 25.404 58.534 -10.293 1.00 8.37 ? 829 TYR A CD2 1 ATOM 6725 C CE1 . TYR A 1 829 ? 23.139 58.674 -11.850 1.00 10.03 ? 829 TYR A CE1 1 ATOM 6726 C CE2 . TYR A 1 829 ? 24.286 57.709 -9.982 1.00 9.66 ? 829 TYR A CE2 1 ATOM 6727 C CZ . TYR A 1 829 ? 23.193 57.804 -10.772 1.00 8.80 ? 829 TYR A CZ 1 ATOM 6728 O OH . TYR A 1 829 ? 22.123 56.974 -10.442 1.00 10.83 ? 829 TYR A OH 1 ATOM 6729 N N . PRO A 1 830 ? 28.890 61.841 -10.227 1.00 7.97 ? 830 PRO A N 1 ATOM 6730 C CA . PRO A 1 830 ? 30.184 62.506 -10.417 1.00 8.54 ? 830 PRO A CA 1 ATOM 6731 C C . PRO A 1 830 ? 30.681 62.231 -11.837 1.00 8.58 ? 830 PRO A C 1 ATOM 6732 O O . PRO A 1 830 ? 30.461 61.141 -12.411 1.00 9.42 ? 830 PRO A O 1 ATOM 6733 C CB . PRO A 1 830 ? 31.119 61.800 -9.403 1.00 12.22 ? 830 PRO A CB 1 ATOM 6734 C CG . PRO A 1 830 ? 30.226 60.896 -8.539 1.00 11.19 ? 830 PRO A CG 1 ATOM 6735 C CD . PRO A 1 830 ? 28.915 60.696 -9.286 1.00 7.99 ? 830 PRO A CD 1 ATOM 6736 N N . ILE A 1 831 ? 31.307 63.248 -12.453 1.00 7.40 ? 831 ILE A N 1 ATOM 6737 C CA . ILE A 1 831 ? 31.946 63.083 -13.769 1.00 8.57 ? 831 ILE A CA 1 ATOM 6738 C C . ILE A 1 831 ? 33.403 63.393 -13.503 1.00 8.19 ? 831 ILE A C 1 ATOM 6739 O O . ILE A 1 831 ? 33.893 64.482 -13.834 1.00 8.69 ? 831 ILE A O 1 ATOM 6740 C CB . ILE A 1 831 ? 31.375 64.035 -14.877 1.00 7.46 ? 831 ILE A CB 1 ATOM 6741 C CG1 . ILE A 1 831 ? 29.832 64.088 -14.880 1.00 8.07 ? 831 ILE A CG1 1 ATOM 6742 C CG2 . ILE A 1 831 ? 31.951 63.572 -16.217 1.00 8.76 ? 831 ILE A CG2 1 ATOM 6743 C CD1 . ILE A 1 831 ? 29.089 62.748 -15.101 1.00 7.41 ? 831 ILE A CD1 1 ATOM 6744 N N . PRO A 1 832 ? 34.137 62.428 -12.921 1.00 7.76 ? 832 PRO A N 1 ATOM 6745 C CA . PRO A 1 832 ? 35.531 62.737 -12.604 1.00 8.57 ? 832 PRO A CA 1 ATOM 6746 C C . PRO A 1 832 ? 36.399 62.871 -13.794 1.00 8.70 ? 832 PRO A C 1 ATOM 6747 O O . PRO A 1 832 ? 37.401 63.622 -13.675 1.00 12.53 ? 832 PRO A O 1 ATOM 6748 C CB . PRO A 1 832 ? 35.969 61.624 -11.590 1.00 8.21 ? 832 PRO A CB 1 ATOM 6749 C CG . PRO A 1 832 ? 34.922 60.565 -11.766 1.00 10.13 ? 832 PRO A CG 1 ATOM 6750 C CD . PRO A 1 832 ? 33.661 61.208 -12.236 1.00 9.16 ? 832 PRO A CD 1 ATOM 6751 N N . SER A 1 833 ? 36.104 62.218 -14.917 1.00 7.83 ? 833 SER A N 1 ATOM 6752 C CA . SER A 1 833 ? 36.948 62.354 -16.109 1.00 8.23 ? 833 SER A CA 1 ATOM 6753 C C . SER A 1 833 ? 36.163 62.185 -17.437 1.00 8.10 ? 833 SER A C 1 ATOM 6754 O O . SER A 1 833 ? 36.696 62.515 -18.484 1.00 7.64 ? 833 SER A O 1 ATOM 6755 C CB . SER A 1 833 ? 38.151 61.419 -16.118 1.00 11.99 ? 833 SER A CB 1 ATOM 6756 O OG . SER A 1 833 ? 37.807 60.124 -16.373 1.00 13.20 ? 833 SER A OG 1 ATOM 6757 N N . GLY A 1 834 ? 34.933 61.655 -17.412 1.00 7.72 ? 834 GLY A N 1 ATOM 6758 C CA . GLY A 1 834 ? 34.220 61.557 -18.682 1.00 8.59 ? 834 GLY A CA 1 ATOM 6759 C C . GLY A 1 834 ? 32.858 60.925 -18.536 1.00 7.09 ? 834 GLY A C 1 ATOM 6760 O O . GLY A 1 834 ? 32.496 60.335 -17.505 1.00 8.54 ? 834 GLY A O 1 ATOM 6761 N N . MET A 1 835 ? 32.077 61.094 -19.615 1.00 7.65 ? 835 MET A N 1 ATOM 6762 C CA . MET A 1 835 ? 30.705 60.548 -19.655 1.00 7.97 ? 835 MET A CA 1 ATOM 6763 C C . MET A 1 835 ? 30.372 60.332 -21.114 1.00 7.43 ? 835 MET A C 1 ATOM 6764 O O . MET A 1 835 ? 30.944 60.953 -22.027 1.00 8.45 ? 835 MET A O 1 ATOM 6765 C CB . MET A 1 835 ? 29.709 61.519 -19.023 1.00 7.80 ? 835 MET A CB 1 ATOM 6766 C CG . MET A 1 835 ? 29.621 62.890 -19.777 1.00 10.31 ? 835 MET A CG 1 ATOM 6767 S SD . MET A 1 835 ? 28.737 64.176 -18.868 1.00 12.69 ? 835 MET A SD 1 ATOM 6768 C CE . MET A 1 835 ? 27.350 63.444 -18.426 1.00 13.32 ? 835 MET A CE 1 ATOM 6769 N N . PHE A 1 836 ? 29.422 59.410 -21.368 1.00 8.00 ? 836 PHE A N 1 ATOM 6770 C CA . PHE A 1 836 ? 28.994 59.191 -22.766 1.00 8.23 ? 836 PHE A CA 1 ATOM 6771 C C . PHE A 1 836 ? 27.599 58.624 -22.803 1.00 8.60 ? 836 PHE A C 1 ATOM 6772 O O . PHE A 1 836 ? 27.058 58.084 -21.835 1.00 8.79 ? 836 PHE A O 1 ATOM 6773 C CB . PHE A 1 836 ? 29.980 58.318 -23.570 1.00 8.30 ? 836 PHE A CB 1 ATOM 6774 C CG . PHE A 1 836 ? 30.173 56.872 -23.120 1.00 8.73 ? 836 PHE A CG 1 ATOM 6775 C CD1 . PHE A 1 836 ? 29.323 55.824 -23.590 1.00 9.72 ? 836 PHE A CD1 1 ATOM 6776 C CD2 . PHE A 1 836 ? 31.271 56.534 -22.321 1.00 9.20 ? 836 PHE A CD2 1 ATOM 6777 C CE1 . PHE A 1 836 ? 29.590 54.487 -23.259 1.00 11.77 ? 836 PHE A CE1 1 ATOM 6778 C CE2 . PHE A 1 836 ? 31.528 55.159 -21.998 1.00 10.59 ? 836 PHE A CE2 1 ATOM 6779 C CZ . PHE A 1 836 ? 30.709 54.142 -22.469 1.00 10.82 ? 836 PHE A CZ 1 ATOM 6780 N N . ILE A 1 837 ? 26.984 58.846 -23.987 1.00 8.19 ? 837 ILE A N 1 ATOM 6781 C CA . ILE A 1 837 ? 25.689 58.229 -24.356 1.00 9.99 ? 837 ILE A CA 1 ATOM 6782 C C . ILE A 1 837 ? 25.889 57.586 -25.708 1.00 8.95 ? 837 ILE A C 1 ATOM 6783 O O . ILE A 1 837 ? 26.758 57.978 -26.518 1.00 9.69 ? 837 ILE A O 1 ATOM 6784 C CB . ILE A 1 837 ? 24.538 59.250 -24.409 1.00 9.65 ? 837 ILE A CB 1 ATOM 6785 C CG1 . ILE A 1 837 ? 24.932 60.470 -25.236 1.00 10.99 ? 837 ILE A CG1 1 ATOM 6786 C CG2 . ILE A 1 837 ? 24.073 59.587 -23.083 1.00 10.66 ? 837 ILE A CG2 1 ATOM 6787 C CD1 . ILE A 1 837 ? 23.689 61.343 -25.691 1.00 11.55 ? 837 ILE A CD1 1 ATOM 6788 N N . GLU A 1 838 ? 25.084 56.530 -25.938 1.00 9.85 ? 838 GLU A N 1 ATOM 6789 C CA . GLU A 1 838 ? 25.154 55.829 -27.207 1.00 10.20 ? 838 GLU A CA 1 ATOM 6790 C C . GLU A 1 838 ? 23.853 55.084 -27.525 1.00 9.28 ? 838 GLU A C 1 ATOM 6791 O O . GLU A 1 838 ? 22.987 54.864 -26.682 1.00 10.80 ? 838 GLU A O 1 ATOM 6792 C CB . GLU A 1 838 ? 26.290 54.795 -27.235 1.00 10.80 ? 838 GLU A CB 1 ATOM 6793 C CG . GLU A 1 838 ? 26.089 53.654 -26.214 1.00 12.05 ? 838 GLU A CG 1 ATOM 6794 C CD . GLU A 1 838 ? 27.221 52.647 -26.183 1.00 14.44 ? 838 GLU A CD 1 ATOM 6795 O OE1 . GLU A 1 838 ? 27.025 51.646 -25.455 1.00 16.82 ? 838 GLU A OE1 1 ATOM 6796 O OE2 . GLU A 1 838 ? 28.235 52.767 -26.842 1.00 16.21 ? 838 GLU A OE2 1 ATOM 6797 N N . ASP A 1 839 ? 23.758 54.802 -28.830 1.00 11.36 ? 839 ASP A N 1 ATOM 6798 C CA . ASP A 1 839 ? 22.680 53.894 -29.284 1.00 10.69 ? 839 ASP A CA 1 ATOM 6799 C C . ASP A 1 839 ? 23.376 52.811 -30.081 1.00 11.93 ? 839 ASP A C 1 ATOM 6800 O O . ASP A 1 839 ? 24.565 52.579 -29.964 1.00 13.65 ? 839 ASP A O 1 ATOM 6801 C CB . ASP A 1 839 ? 21.562 54.608 -30.055 1.00 11.82 ? 839 ASP A CB 1 ATOM 6802 C CG . ASP A 1 839 ? 22.036 55.335 -31.312 1.00 12.10 ? 839 ASP A CG 1 ATOM 6803 O OD1 . ASP A 1 839 ? 23.066 54.967 -31.891 1.00 13.44 ? 839 ASP A OD1 1 ATOM 6804 O OD2 . ASP A 1 839 ? 21.248 56.283 -31.703 1.00 16.41 ? 839 ASP A OD2 1 ATOM 6805 N N . ALA A 1 840 ? 22.615 52.088 -30.918 1.00 13.58 ? 840 ALA A N 1 ATOM 6806 C CA . ALA A 1 840 ? 23.253 51.056 -31.685 1.00 15.68 ? 840 ALA A CA 1 ATOM 6807 C C . ALA A 1 840 ? 24.347 51.510 -32.629 1.00 14.58 ? 840 ALA A C 1 ATOM 6808 O O . ALA A 1 840 ? 25.303 50.771 -32.894 1.00 15.93 ? 840 ALA A O 1 ATOM 6809 C CB . ALA A 1 840 ? 22.195 50.256 -32.512 1.00 17.87 ? 840 ALA A CB 1 ATOM 6810 N N . ASN A 1 841 ? 24.257 52.747 -33.108 1.00 12.62 ? 841 ASN A N 1 ATOM 6811 C CA . ASN A 1 841 ? 25.173 53.225 -34.110 1.00 12.66 ? 841 ASN A CA 1 ATOM 6812 C C . ASN A 1 841 ? 26.146 54.337 -33.787 1.00 10.29 ? 841 ASN A C 1 ATOM 6813 O O . ASN A 1 841 ? 27.188 54.432 -34.417 1.00 12.92 ? 841 ASN A O 1 ATOM 6814 C CB . ASN A 1 841 ? 24.332 53.651 -35.363 1.00 13.50 ? 841 ASN A CB 1 ATOM 6815 C CG . ASN A 1 841 ? 23.577 52.464 -35.958 1.00 17.91 ? 841 ASN A CG 1 ATOM 6816 O OD1 . ASN A 1 841 ? 24.155 51.396 -36.136 1.00 19.98 ? 841 ASN A OD1 1 ATOM 6817 N ND2 . ASN A 1 841 ? 22.307 52.651 -36.217 1.00 21.96 ? 841 ASN A ND2 1 ATOM 6818 N N . THR A 1 842 ? 25.728 55.145 -32.833 1.00 10.93 ? 842 THR A N 1 ATOM 6819 C CA . THR A 1 842 ? 26.463 56.398 -32.564 1.00 10.94 ? 842 THR A CA 1 ATOM 6820 C C . THR A 1 842 ? 26.693 56.552 -31.069 1.00 9.98 ? 842 THR A C 1 ATOM 6821 O O . THR A 1 842 ? 25.808 56.278 -30.256 1.00 12.13 ? 842 THR A O 1 ATOM 6822 C CB . THR A 1 842 ? 25.617 57.619 -33.051 1.00 10.90 ? 842 THR A CB 1 ATOM 6823 O OG1 . THR A 1 842 ? 25.250 57.414 -34.442 1.00 14.91 ? 842 THR A OG1 1 ATOM 6824 C CG2 . THR A 1 842 ? 26.419 58.879 -33.058 1.00 14.50 ? 842 THR A CG2 1 ATOM 6825 N N . ARG A 1 843 ? 27.849 57.144 -30.785 1.00 10.56 ? 843 ARG A N 1 ATOM 6826 C CA . ARG A 1 843 ? 28.224 57.467 -29.396 1.00 9.93 ? 843 ARG A CA 1 ATOM 6827 C C . ARG A 1 843 ? 28.768 58.925 -29.347 1.00 9.06 ? 843 ARG A C 1 ATOM 6828 O O . ARG A 1 843 ? 29.462 59.363 -30.265 1.00 10.11 ? 843 ARG A O 1 ATOM 6829 C CB . ARG A 1 843 ? 29.331 56.543 -28.878 1.00 10.06 ? 843 ARG A CB 1 ATOM 6830 C CG . ARG A 1 843 ? 29.717 56.830 -27.376 1.00 9.69 ? 843 ARG A CG 1 ATOM 6831 C CD . ARG A 1 843 ? 30.889 55.998 -26.946 1.00 9.35 ? 843 ARG A CD 1 ATOM 6832 N NE . ARG A 1 843 ? 30.510 54.595 -26.681 1.00 10.50 ? 843 ARG A NE 1 ATOM 6833 C CZ . ARG A 1 843 ? 31.350 53.748 -26.104 1.00 11.70 ? 843 ARG A CZ 1 ATOM 6834 N NH1 . ARG A 1 843 ? 32.586 54.091 -25.755 1.00 11.72 ? 843 ARG A NH1 1 ATOM 6835 N NH2 . ARG A 1 843 ? 30.908 52.511 -25.775 1.00 12.29 ? 843 ARG A NH2 1 ATOM 6836 N N . LEU A 1 844 ? 28.406 59.627 -28.279 1.00 8.93 ? 844 LEU A N 1 ATOM 6837 C CA . LEU A 1 844 ? 28.986 60.980 -28.010 1.00 8.49 ? 844 LEU A CA 1 ATOM 6838 C C . LEU A 1 844 ? 29.635 60.880 -26.601 1.00 8.52 ? 844 LEU A C 1 ATOM 6839 O O . LEU A 1 844 ? 28.979 60.530 -25.629 1.00 9.23 ? 844 LEU A O 1 ATOM 6840 C CB . LEU A 1 844 ? 27.908 62.046 -27.980 1.00 9.57 ? 844 LEU A CB 1 ATOM 6841 C CG . LEU A 1 844 ? 28.541 63.471 -27.879 1.00 10.63 ? 844 LEU A CG 1 ATOM 6842 C CD1 . LEU A 1 844 ? 29.442 63.795 -29.083 1.00 12.92 ? 844 LEU A CD1 1 ATOM 6843 C CD2 . LEU A 1 844 ? 27.459 64.474 -27.744 1.00 12.95 ? 844 LEU A CD2 1 ATOM 6844 N N . THR A 1 845 ? 30.951 61.119 -26.592 1.00 9.14 ? 845 THR A N 1 ATOM 6845 C CA . THR A 1 845 ? 31.717 61.060 -25.309 1.00 9.05 ? 845 THR A CA 1 ATOM 6846 C C . THR A 1 845 ? 32.262 62.476 -25.013 1.00 8.25 ? 845 THR A C 1 ATOM 6847 O O . THR A 1 845 ? 32.862 63.102 -25.891 1.00 9.09 ? 845 THR A O 1 ATOM 6848 C CB . THR A 1 845 ? 32.923 60.110 -25.416 1.00 8.12 ? 845 THR A CB 1 ATOM 6849 O OG1 . THR A 1 845 ? 32.460 58.790 -25.816 1.00 9.72 ? 845 THR A OG1 1 ATOM 6850 C CG2 . THR A 1 845 ? 33.649 59.920 -24.067 1.00 9.66 ? 845 THR A CG2 1 ATOM 6851 N N . LEU A 1 846 ? 32.066 62.920 -23.786 1.00 8.16 ? 846 LEU A N 1 ATOM 6852 C CA . LEU A 1 846 ? 32.630 64.193 -23.338 1.00 8.07 ? 846 LEU A CA 1 ATOM 6853 C C . LEU A 1 846 ? 33.686 63.842 -22.267 1.00 7.20 ? 846 LEU A C 1 ATOM 6854 O O . LEU A 1 846 ? 33.313 63.246 -21.206 1.00 8.00 ? 846 LEU A O 1 ATOM 6855 C CB . LEU A 1 846 ? 31.540 65.068 -22.758 1.00 9.43 ? 846 LEU A CB 1 ATOM 6856 C CG . LEU A 1 846 ? 32.028 66.422 -22.230 1.00 9.21 ? 846 LEU A CG 1 ATOM 6857 C CD1 . LEU A 1 846 ? 32.454 67.331 -23.404 1.00 10.84 ? 846 LEU A CD1 1 ATOM 6858 C CD2 . LEU A 1 846 ? 30.919 67.097 -21.396 1.00 14.75 ? 846 LEU A CD2 1 ATOM 6859 N N . LEU A 1 847 ? 34.950 64.145 -22.541 1.00 8.36 ? 847 LEU A N 1 ATOM 6860 C CA . LEU A 1 847 ? 36.068 63.901 -21.585 1.00 7.46 ? 847 LEU A CA 1 ATOM 6861 C C . LEU A 1 847 ? 36.317 65.211 -20.870 1.00 7.57 ? 847 LEU A C 1 ATOM 6862 O O . LEU A 1 847 ? 36.223 66.295 -21.505 1.00 7.72 ? 847 LEU A O 1 ATOM 6863 C CB . LEU A 1 847 ? 37.330 63.450 -22.287 1.00 8.35 ? 847 LEU A CB 1 ATOM 6864 C CG . LEU A 1 847 ? 37.315 62.089 -22.979 1.00 8.20 ? 847 LEU A CG 1 ATOM 6865 C CD1 . LEU A 1 847 ? 36.662 60.987 -22.123 1.00 8.98 ? 847 LEU A CD1 1 ATOM 6866 C CD2 . LEU A 1 847 ? 36.598 62.187 -24.363 1.00 10.33 ? 847 LEU A CD2 1 ATOM 6867 N N . THR A 1 848 ? 36.659 65.145 -19.569 1.00 7.81 ? 848 THR A N 1 ATOM 6868 C CA . THR A 1 848 ? 36.886 66.377 -18.783 1.00 7.70 ? 848 THR A CA 1 ATOM 6869 C C . THR A 1 848 ? 38.288 66.466 -18.176 1.00 8.48 ? 848 THR A C 1 ATOM 6870 O O . THR A 1 848 ? 38.982 65.438 -17.923 1.00 9.64 ? 848 THR A O 1 ATOM 6871 C CB . THR A 1 848 ? 35.927 66.485 -17.637 1.00 9.81 ? 848 THR A CB 1 ATOM 6872 O OG1 . THR A 1 848 ? 36.388 65.585 -16.572 1.00 13.81 ? 848 THR A OG1 1 ATOM 6873 C CG2 . THR A 1 848 ? 34.535 66.195 -17.997 1.00 12.65 ? 848 THR A CG2 1 ATOM 6874 N N . GLY A 1 849 ? 38.762 67.709 -18.037 1.00 7.10 ? 849 GLY A N 1 ATOM 6875 C CA . GLY A 1 849 ? 40.019 67.947 -17.376 1.00 7.55 ? 849 GLY A CA 1 ATOM 6876 C C . GLY A 1 849 ? 39.849 68.289 -15.904 1.00 7.43 ? 849 GLY A C 1 ATOM 6877 O O . GLY A 1 849 ? 40.810 68.714 -15.240 1.00 7.60 ? 849 GLY A O 1 ATOM 6878 N N . GLN A 1 850 ? 38.668 68.113 -15.357 1.00 6.92 ? 850 GLN A N 1 ATOM 6879 C CA . GLN A 1 850 ? 38.365 68.410 -13.971 1.00 7.22 ? 850 GLN A CA 1 ATOM 6880 C C . GLN A 1 850 ? 37.084 67.666 -13.583 1.00 6.83 ? 850 GLN A C 1 ATOM 6881 O O . GLN A 1 850 ? 36.196 67.467 -14.435 1.00 7.99 ? 850 GLN A O 1 ATOM 6882 C CB . GLN A 1 850 ? 38.160 69.962 -13.785 1.00 7.83 ? 850 GLN A CB 1 ATOM 6883 C CG . GLN A 1 850 ? 36.992 70.552 -14.705 1.00 7.49 ? 850 GLN A CG 1 ATOM 6884 C CD . GLN A 1 850 ? 37.359 70.660 -16.161 1.00 7.97 ? 850 GLN A CD 1 ATOM 6885 O OE1 . GLN A 1 850 ? 38.480 71.073 -16.538 1.00 8.73 ? 850 GLN A OE1 1 ATOM 6886 N NE2 . GLN A 1 850 ? 36.421 70.307 -17.042 1.00 7.75 ? 850 GLN A NE2 1 ATOM 6887 N N . PRO A 1 851 ? 36.939 67.277 -12.317 1.00 6.13 ? 851 PRO A N 1 ATOM 6888 C CA . PRO A 1 851 ? 35.707 66.580 -11.885 1.00 6.43 ? 851 PRO A CA 1 ATOM 6889 C C . PRO A 1 851 ? 34.600 67.598 -11.689 1.00 6.74 ? 851 PRO A C 1 ATOM 6890 O O . PRO A 1 851 ? 34.777 68.640 -11.024 1.00 7.85 ? 851 PRO A O 1 ATOM 6891 C CB . PRO A 1 851 ? 36.116 65.894 -10.566 1.00 7.46 ? 851 PRO A CB 1 ATOM 6892 C CG . PRO A 1 851 ? 37.230 66.833 -10.005 1.00 6.47 ? 851 PRO A CG 1 ATOM 6893 C CD . PRO A 1 851 ? 37.961 67.338 -11.248 1.00 6.24 ? 851 PRO A CD 1 ATOM 6894 N N . LEU A 1 852 ? 33.422 67.266 -12.239 1.00 7.54 ? 852 LEU A N 1 ATOM 6895 C CA . LEU A 1 852 ? 32.226 68.100 -12.141 1.00 8.84 ? 852 LEU A CA 1 ATOM 6896 C C . LEU A 1 852 ? 30.997 67.199 -12.047 1.00 9.49 ? 852 LEU A C 1 ATOM 6897 O O . LEU A 1 852 ? 31.127 65.992 -12.297 1.00 14.43 ? 852 LEU A O 1 ATOM 6898 C CB . LEU A 1 852 ? 32.092 68.982 -13.394 1.00 8.73 ? 852 LEU A CB 1 ATOM 6899 C CG . LEU A 1 852 ? 33.263 70.008 -13.549 1.00 7.40 ? 852 LEU A CG 1 ATOM 6900 C CD1 . LEU A 1 852 ? 33.243 70.611 -14.985 1.00 9.37 ? 852 LEU A CD1 1 ATOM 6901 C CD2 . LEU A 1 852 ? 33.185 71.118 -12.553 1.00 9.21 ? 852 LEU A CD2 1 ATOM 6902 N N . GLY A 1 853 ? 29.843 67.691 -11.689 1.00 7.41 ? 853 GLY A N 1 ATOM 6903 C CA . GLY A 1 853 ? 28.647 66.833 -11.670 1.00 8.32 ? 853 GLY A CA 1 ATOM 6904 C C . GLY A 1 853 ? 27.905 66.847 -12.963 1.00 8.40 ? 853 GLY A C 1 ATOM 6905 O O . GLY A 1 853 ? 27.924 67.838 -13.721 1.00 8.21 ? 853 GLY A O 1 ATOM 6906 N N . GLY A 1 854 ? 27.232 65.753 -13.289 1.00 7.25 ? 854 GLY A N 1 ATOM 6907 C CA . GLY A 1 854 ? 26.522 65.727 -14.556 1.00 9.38 ? 854 GLY A CA 1 ATOM 6908 C C . GLY A 1 854 ? 25.498 64.615 -14.643 1.00 7.27 ? 854 GLY A C 1 ATOM 6909 O O . GLY A 1 854 ? 25.344 63.785 -13.738 1.00 8.50 ? 854 GLY A O 1 ATOM 6910 N N . SER A 1 855 ? 24.808 64.596 -15.795 1.00 9.11 ? 855 SER A N 1 ATOM 6911 C CA . SER A 1 855 ? 23.748 63.596 -15.995 1.00 9.52 ? 855 SER A CA 1 ATOM 6912 C C . SER A 1 855 ? 23.358 63.578 -17.450 1.00 9.41 ? 855 SER A C 1 ATOM 6913 O O . SER A 1 855 ? 23.913 64.238 -18.329 1.00 9.69 ? 855 SER A O 1 ATOM 6914 C CB . SER A 1 855 ? 22.524 64.056 -15.201 1.00 10.27 ? 855 SER A CB 1 ATOM 6915 O OG . SER A 1 855 ? 21.489 63.051 -15.166 1.00 11.13 ? 855 SER A OG 1 ATOM 6916 N N . SER A 1 856 ? 22.349 62.710 -17.698 1.00 10.25 ? 856 SER A N 1 ATOM 6917 C CA . SER A 1 856 ? 21.642 62.678 -19.026 1.00 9.84 ? 856 SER A CA 1 ATOM 6918 C C . SER A 1 856 ? 20.167 62.667 -18.611 1.00 11.12 ? 856 SER A C 1 ATOM 6919 O O . SER A 1 856 ? 19.646 61.605 -18.216 1.00 12.30 ? 856 SER A O 1 ATOM 6920 C CB . SER A 1 856 ? 22.027 61.419 -19.791 1.00 9.72 ? 856 SER A CB 1 ATOM 6921 O OG . SER A 1 856 ? 21.146 61.332 -20.956 1.00 10.87 ? 856 SER A OG 1 ATOM 6922 N N . LEU A 1 857 ? 19.494 63.836 -18.608 1.00 11.33 ? 857 LEU A N 1 ATOM 6923 C CA . LEU A 1 857 ? 18.132 63.936 -18.118 1.00 11.85 ? 857 LEU A CA 1 ATOM 6924 C C . LEU A 1 857 ? 17.060 63.612 -19.161 1.00 12.11 ? 857 LEU A C 1 ATOM 6925 O O . LEU A 1 857 ? 15.872 63.592 -18.792 1.00 12.38 ? 857 LEU A O 1 ATOM 6926 C CB . LEU A 1 857 ? 17.903 65.345 -17.512 1.00 12.04 ? 857 LEU A CB 1 ATOM 6927 C CG . LEU A 1 857 ? 18.747 65.611 -16.273 1.00 12.08 ? 857 LEU A CG 1 ATOM 6928 C CD1 . LEU A 1 857 ? 18.558 67.111 -15.832 1.00 13.42 ? 857 LEU A CD1 1 ATOM 6929 C CD2 . LEU A 1 857 ? 18.390 64.634 -15.119 1.00 14.74 ? 857 LEU A CD2 1 ATOM 6930 N N . ALA A 1 858 ? 17.487 63.347 -20.345 1.00 10.30 ? 858 ALA A N 1 ATOM 6931 C CA . ALA A 1 858 ? 16.570 62.945 -21.439 1.00 9.99 ? 858 ALA A CA 1 ATOM 6932 C C . ALA A 1 858 ? 17.369 62.273 -22.491 1.00 13.29 ? 858 ALA A C 1 ATOM 6933 O O . ALA A 1 858 ? 18.591 62.492 -22.644 1.00 11.10 ? 858 ALA A O 1 ATOM 6934 C CB . ALA A 1 858 ? 15.811 64.191 -22.073 1.00 13.95 ? 858 ALA A CB 1 ATOM 6935 N N . SER A 1 859 ? 16.743 61.399 -23.285 1.00 12.11 ? 859 SER A N 1 ATOM 6936 C CA . SER A 1 859 ? 17.391 60.668 -24.321 1.00 11.59 ? 859 SER A CA 1 ATOM 6937 C C . SER A 1 859 ? 18.127 61.609 -25.248 1.00 9.51 ? 859 SER A C 1 ATOM 6938 O O . SER A 1 859 ? 17.553 62.683 -25.601 1.00 12.95 ? 859 SER A O 1 ATOM 6939 C CB . SER A 1 859 ? 16.310 59.845 -25.107 1.00 12.45 ? 859 SER A CB 1 ATOM 6940 O OG . SER A 1 859 ? 16.836 59.074 -26.082 1.00 13.74 ? 859 SER A OG 1 ATOM 6941 N N . GLY A 1 860 ? 19.344 61.259 -25.619 1.00 11.17 ? 860 GLY A N 1 ATOM 6942 C CA . GLY A 1 860 ? 20.142 62.087 -26.505 1.00 11.12 ? 860 GLY A CA 1 ATOM 6943 C C . GLY A 1 860 ? 20.889 63.248 -25.833 1.00 9.90 ? 860 GLY A C 1 ATOM 6944 O O . GLY A 1 860 ? 21.634 63.924 -26.554 1.00 11.43 ? 860 GLY A O 1 ATOM 6945 N N . GLU A 1 861 ? 20.700 63.449 -24.539 1.00 9.73 ? 861 GLU A N 1 ATOM 6946 C CA . GLU A 1 861 ? 21.392 64.569 -23.869 1.00 11.03 ? 861 GLU A CA 1 ATOM 6947 C C . GLU A 1 861 ? 22.530 64.166 -22.951 1.00 11.68 ? 861 GLU A C 1 ATOM 6948 O O . GLU A 1 861 ? 22.591 63.051 -22.419 1.00 11.53 ? 861 GLU A O 1 ATOM 6949 C CB . GLU A 1 861 ? 20.462 65.345 -22.996 1.00 12.57 ? 861 GLU A CB 1 ATOM 6950 C CG . GLU A 1 861 ? 19.349 66.007 -23.736 1.00 14.75 ? 861 GLU A CG 1 ATOM 6951 C CD . GLU A 1 861 ? 18.423 66.832 -22.819 1.00 17.99 ? 861 GLU A CD 1 ATOM 6952 O OE1 . GLU A 1 861 ? 18.540 66.895 -21.562 1.00 16.89 ? 861 GLU A OE1 1 ATOM 6953 O OE2 . GLU A 1 861 ? 17.453 67.482 -23.362 1.00 19.93 ? 861 GLU A OE2 1 ATOM 6954 N N . LEU A 1 862 ? 23.458 65.086 -22.799 1.00 10.95 ? 862 LEU A N 1 ATOM 6955 C CA . LEU A 1 862 ? 24.510 64.979 -21.754 1.00 11.27 ? 862 LEU A CA 1 ATOM 6956 C C . LEU A 1 862 ? 24.523 66.370 -21.129 1.00 9.72 ? 862 LEU A C 1 ATOM 6957 O O . LEU A 1 862 ? 24.329 67.386 -21.854 1.00 10.16 ? 862 LEU A O 1 ATOM 6958 C CB . LEU A 1 862 ? 25.916 64.705 -22.366 1.00 11.72 ? 862 LEU A CB 1 ATOM 6959 C CG . LEU A 1 862 ? 26.255 63.364 -23.009 1.00 11.62 ? 862 LEU A CG 1 ATOM 6960 C CD1 . LEU A 1 862 ? 27.612 63.424 -23.670 1.00 11.94 ? 862 LEU A CD1 1 ATOM 6961 C CD2 . LEU A 1 862 ? 26.175 62.266 -21.948 1.00 11.93 ? 862 LEU A CD2 1 ATOM 6962 N N . GLU A 1 863 ? 24.791 66.487 -19.839 1.00 8.89 ? 863 GLU A N 1 ATOM 6963 C CA . GLU A 1 863 ? 24.993 67.814 -19.274 1.00 8.63 ? 863 GLU A CA 1 ATOM 6964 C C . GLU A 1 863 ? 25.988 67.727 -18.137 1.00 9.08 ? 863 GLU A C 1 ATOM 6965 O O . GLU A 1 863 ? 26.102 66.699 -17.452 1.00 8.27 ? 863 GLU A O 1 ATOM 6966 C CB . GLU A 1 863 ? 23.694 68.477 -18.823 1.00 10.20 ? 863 GLU A CB 1 ATOM 6967 C CG . GLU A 1 863 ? 23.061 67.863 -17.584 1.00 10.55 ? 863 GLU A CG 1 ATOM 6968 C CD . GLU A 1 863 ? 21.772 68.602 -17.173 1.00 11.00 ? 863 GLU A CD 1 ATOM 6969 O OE1 . GLU A 1 863 ? 21.619 69.128 -16.064 1.00 11.48 ? 863 GLU A OE1 1 ATOM 6970 O OE2 . GLU A 1 863 ? 20.886 68.638 -18.079 1.00 13.18 ? 863 GLU A OE2 1 ATOM 6971 N N . ILE A 1 864 ? 26.692 68.838 -17.948 1.00 9.29 ? 864 ILE A N 1 ATOM 6972 C CA . ILE A 1 864 ? 27.732 68.881 -16.877 1.00 9.05 ? 864 ILE A CA 1 ATOM 6973 C C . ILE A 1 864 ? 27.739 70.297 -16.262 1.00 8.19 ? 864 ILE A C 1 ATOM 6974 O O . ILE A 1 864 ? 27.760 71.312 -17.014 1.00 8.30 ? 864 ILE A O 1 ATOM 6975 C CB . ILE A 1 864 ? 29.098 68.439 -17.497 1.00 9.58 ? 864 ILE A CB 1 ATOM 6976 C CG1 . ILE A 1 864 ? 30.178 68.378 -16.414 1.00 11.45 ? 864 ILE A CG1 1 ATOM 6977 C CG2 . ILE A 1 864 ? 29.471 69.336 -18.646 1.00 12.29 ? 864 ILE A CG2 1 ATOM 6978 C CD1 . ILE A 1 864 ? 31.352 67.480 -16.909 1.00 11.29 ? 864 ILE A CD1 1 ATOM 6979 N N . MET A 1 865 ? 27.692 70.363 -14.947 1.00 8.40 ? 865 MET A N 1 ATOM 6980 C CA . MET A 1 865 ? 27.663 71.627 -14.243 1.00 8.59 ? 865 MET A CA 1 ATOM 6981 C C . MET A 1 865 ? 29.018 72.311 -14.296 1.00 8.71 ? 865 MET A C 1 ATOM 6982 O O . MET A 1 865 ? 30.078 71.674 -14.115 1.00 10.21 ? 865 MET A O 1 ATOM 6983 C CB . MET A 1 865 ? 27.216 71.363 -12.812 1.00 8.81 ? 865 MET A CB 1 ATOM 6984 C CG . MET A 1 865 ? 26.587 72.613 -12.136 1.00 8.97 ? 865 MET A CG 1 ATOM 6985 S SD . MET A 1 865 ? 24.961 73.021 -12.869 1.00 11.45 ? 865 MET A SD 1 ATOM 6986 C CE . MET A 1 865 ? 23.959 71.807 -11.955 1.00 12.21 ? 865 MET A CE 1 ATOM 6987 N N . GLN A 1 866 ? 28.997 73.644 -14.460 1.00 9.24 ? 866 GLN A N 1 ATOM 6988 C CA . GLN A 1 866 ? 30.225 74.429 -14.596 1.00 8.31 ? 866 GLN A CA 1 ATOM 6989 C C . GLN A 1 866 ? 30.603 75.115 -13.301 1.00 8.06 ? 866 GLN A C 1 ATOM 6990 O O . GLN A 1 866 ? 31.790 75.182 -12.933 1.00 9.00 ? 866 GLN A O 1 ATOM 6991 C CB . GLN A 1 866 ? 30.040 75.487 -15.720 1.00 9.59 ? 866 GLN A CB 1 ATOM 6992 C CG . GLN A 1 866 ? 29.712 74.862 -17.089 1.00 9.21 ? 866 GLN A CG 1 ATOM 6993 C CD . GLN A 1 866 ? 30.735 73.866 -17.503 1.00 9.20 ? 866 GLN A CD 1 ATOM 6994 O OE1 . GLN A 1 866 ? 31.874 74.218 -17.847 1.00 10.77 ? 866 GLN A OE1 1 ATOM 6995 N NE2 . GLN A 1 866 ? 30.358 72.587 -17.480 1.00 10.09 ? 866 GLN A NE2 1 ATOM 6996 N N . ASP A 1 867 ? 29.625 75.751 -12.640 1.00 9.52 ? 867 ASP A N 1 ATOM 6997 C CA . ASP A 1 867 ? 29.876 76.384 -11.327 1.00 9.21 ? 867 ASP A CA 1 ATOM 6998 C C . ASP A 1 867 ? 28.548 76.623 -10.658 1.00 8.49 ? 867 ASP A C 1 ATOM 6999 O O . ASP A 1 867 ? 27.462 76.517 -11.341 1.00 9.12 ? 867 ASP A O 1 ATOM 7000 C CB . ASP A 1 867 ? 30.702 77.698 -11.450 1.00 9.16 ? 867 ASP A CB 1 ATOM 7001 C CG . ASP A 1 867 ? 31.387 78.072 -10.135 1.00 9.23 ? 867 ASP A CG 1 ATOM 7002 O OD1 . ASP A 1 867 ? 31.239 77.425 -9.082 1.00 9.48 ? 867 ASP A OD1 1 ATOM 7003 O OD2 . ASP A 1 867 ? 32.105 79.101 -10.191 1.00 11.27 ? 867 ASP A OD2 1 ATOM 7004 N N . ARG A 1 868 ? 28.582 76.915 -9.393 1.00 9.05 ? 868 ARG A N 1 ATOM 7005 C CA . ARG A 1 868 ? 27.370 77.123 -8.620 1.00 9.36 ? 868 ARG A CA 1 ATOM 7006 C C . ARG A 1 868 ? 27.703 78.132 -7.524 1.00 10.12 ? 868 ARG A C 1 ATOM 7007 O O . ARG A 1 868 ? 28.742 78.057 -6.881 1.00 10.77 ? 868 ARG A O 1 ATOM 7008 C CB . ARG A 1 868 ? 26.857 75.768 -8.024 1.00 8.97 ? 868 ARG A CB 1 ATOM 7009 C CG . ARG A 1 868 ? 27.833 75.025 -7.148 1.00 9.41 ? 868 ARG A CG 1 ATOM 7010 C CD . ARG A 1 868 ? 27.580 73.480 -7.180 1.00 9.78 ? 868 ARG A CD 1 ATOM 7011 N NE . ARG A 1 868 ? 26.200 73.163 -6.751 1.00 9.32 ? 868 ARG A NE 1 ATOM 7012 C CZ . ARG A 1 868 ? 25.860 72.884 -5.513 1.00 9.11 ? 868 ARG A CZ 1 ATOM 7013 N NH1 . ARG A 1 868 ? 26.755 72.799 -4.512 1.00 8.99 ? 868 ARG A NH1 1 ATOM 7014 N NH2 . ARG A 1 868 ? 24.550 72.752 -5.238 1.00 11.01 ? 868 ARG A NH2 1 ATOM 7015 N N . ARG A 1 869 ? 26.769 79.089 -7.316 1.00 10.36 ? 869 ARG A N 1 ATOM 7016 C CA . ARG A 1 869 ? 26.927 80.162 -6.318 1.00 10.46 ? 869 ARG A CA 1 ATOM 7017 C C . ARG A 1 869 ? 25.642 80.149 -5.527 1.00 12.17 ? 869 ARG A C 1 ATOM 7018 O O . ARG A 1 869 ? 24.555 80.353 -6.096 1.00 12.46 ? 869 ARG A O 1 ATOM 7019 C CB . ARG A 1 869 ? 27.194 81.476 -7.062 1.00 11.75 ? 869 ARG A CB 1 ATOM 7020 C CG . ARG A 1 869 ? 27.367 82.638 -6.112 1.00 11.49 ? 869 ARG A CG 1 ATOM 7021 C CD . ARG A 1 869 ? 27.695 83.894 -6.907 1.00 15.26 ? 869 ARG A CD 1 ATOM 7022 N NE . ARG A 1 869 ? 27.822 85.081 -6.034 1.00 17.54 ? 869 ARG A NE 1 ATOM 7023 C CZ . ARG A 1 869 ? 28.932 85.428 -5.412 1.00 15.99 ? 869 ARG A CZ 1 ATOM 7024 N NH1 . ARG A 1 869 ? 30.017 84.720 -5.545 1.00 15.75 ? 869 ARG A NH1 1 ATOM 7025 N NH2 . ARG A 1 869 ? 28.945 86.529 -4.625 1.00 19.63 ? 869 ARG A NH2 1 ATOM 7026 N N . LEU A 1 870 ? 25.782 79.866 -4.249 1.00 12.72 ? 870 LEU A N 1 ATOM 7027 C CA . LEU A 1 870 ? 24.635 79.640 -3.346 1.00 12.71 ? 870 LEU A CA 1 ATOM 7028 C C . LEU A 1 870 ? 24.730 80.489 -2.109 1.00 14.21 ? 870 LEU A C 1 ATOM 7029 O O . LEU A 1 870 ? 25.674 80.428 -1.373 1.00 14.72 ? 870 LEU A O 1 ATOM 7030 C CB . LEU A 1 870 ? 24.626 78.167 -2.949 1.00 13.01 ? 870 LEU A CB 1 ATOM 7031 C CG . LEU A 1 870 ? 24.599 77.302 -4.221 1.00 18.69 ? 870 LEU A CG 1 ATOM 7032 C CD1 . LEU A 1 870 ? 25.119 75.977 -3.860 1.00 18.97 ? 870 LEU A CD1 1 ATOM 7033 C CD2 . LEU A 1 870 ? 23.266 77.275 -4.966 1.00 15.33 ? 870 LEU A CD2 1 ATOM 7034 N N . ALA A 1 871 ? 23.637 81.206 -1.838 1.00 14.60 ? 871 ALA A N 1 ATOM 7035 C CA . ALA A 1 871 ? 23.658 82.108 -0.685 1.00 17.00 ? 871 ALA A CA 1 ATOM 7036 C C . ALA A 1 871 ? 23.379 81.433 0.665 1.00 19.42 ? 871 ALA A C 1 ATOM 7037 O O . ALA A 1 871 ? 23.783 81.939 1.709 1.00 22.48 ? 871 ALA A O 1 ATOM 7038 C CB . ALA A 1 871 ? 22.617 83.233 -0.931 1.00 18.70 ? 871 ALA A CB 1 ATOM 7039 N N . SER A 1 872 ? 22.738 80.280 0.630 1.00 17.08 ? 872 SER A N 1 ATOM 7040 C CA . SER A 1 872 ? 22.339 79.593 1.858 1.00 17.72 ? 872 SER A CA 1 ATOM 7041 C C . SER A 1 872 ? 23.195 78.427 2.278 1.00 15.14 ? 872 SER A C 1 ATOM 7042 O O . SER A 1 872 ? 23.841 77.801 1.428 1.00 17.14 ? 872 SER A O 1 ATOM 7043 C CB . SER A 1 872 ? 20.897 79.068 1.663 1.00 20.64 ? 872 SER A CB 1 ATOM 7044 O OG . SER A 1 872 ? 19.984 80.146 1.474 1.00 25.93 ? 872 SER A OG 1 ATOM 7045 N N . ASP A 1 873 ? 23.222 78.171 3.580 1.00 15.83 ? 873 ASP A N 1 ATOM 7046 C CA . ASP A 1 873 ? 23.885 76.989 4.151 1.00 16.48 ? 873 ASP A CA 1 ATOM 7047 C C . ASP A 1 873 ? 22.844 75.846 3.979 1.00 16.21 ? 873 ASP A C 1 ATOM 7048 O O . ASP A 1 873 ? 21.614 76.084 4.022 1.00 17.30 ? 873 ASP A O 1 ATOM 7049 C CB . ASP A 1 873 ? 24.176 77.211 5.642 1.00 16.23 ? 873 ASP A CB 1 ATOM 7050 C CG . ASP A 1 873 ? 24.642 75.936 6.335 1.00 16.47 ? 873 ASP A CG 1 ATOM 7051 O OD1 . ASP A 1 873 ? 23.894 75.383 7.177 1.00 20.02 ? 873 ASP A OD1 1 ATOM 7052 O OD2 . ASP A 1 873 ? 25.752 75.456 5.961 1.00 18.27 ? 873 ASP A OD2 1 ATOM 7053 N N . ASP A 1 874 ? 23.331 74.610 3.805 1.00 14.46 ? 874 ASP A N 1 ATOM 7054 C CA . ASP A 1 874 ? 22.462 73.443 3.594 1.00 11.71 ? 874 ASP A CA 1 ATOM 7055 C C . ASP A 1 874 ? 22.411 72.498 4.783 1.00 13.03 ? 874 ASP A C 1 ATOM 7056 O O . ASP A 1 874 ? 22.180 71.285 4.617 1.00 14.24 ? 874 ASP A O 1 ATOM 7057 C CB . ASP A 1 874 ? 22.803 72.706 2.286 1.00 10.79 ? 874 ASP A CB 1 ATOM 7058 C CG . ASP A 1 874 ? 24.283 72.379 2.156 1.00 10.32 ? 874 ASP A CG 1 ATOM 7059 O OD1 . ASP A 1 874 ? 25.073 72.706 3.106 1.00 13.53 ? 874 ASP A OD1 1 ATOM 7060 O OD2 . ASP A 1 874 ? 24.609 71.810 1.095 1.00 11.68 ? 874 ASP A OD2 1 ATOM 7061 N N . GLU A 1 875 ? 22.670 73.031 5.974 1.00 13.36 ? 875 GLU A N 1 ATOM 7062 C CA . GLU A 1 875 ? 22.453 72.295 7.221 1.00 15.45 ? 875 GLU A CA 1 ATOM 7063 C C . GLU A 1 875 ? 23.215 71.029 7.437 1.00 15.15 ? 875 GLU A C 1 ATOM 7064 O O . GLU A 1 875 ? 22.716 70.099 8.091 1.00 15.58 ? 875 GLU A O 1 ATOM 7065 C CB . GLU A 1 875 ? 20.941 71.968 7.405 1.00 20.75 ? 875 GLU A CB 1 ATOM 7066 C CG . GLU A 1 875 ? 20.022 73.159 7.139 1.00 27.02 ? 875 GLU A CG 1 ATOM 7067 C CD . GLU A 1 875 ? 18.790 73.119 8.002 1.00 35.16 ? 875 GLU A CD 1 ATOM 7068 O OE1 . GLU A 1 875 ? 18.914 73.328 9.234 1.00 43.55 ? 875 GLU A OE1 1 ATOM 7069 O OE2 . GLU A 1 875 ? 17.700 72.871 7.461 1.00 39.85 ? 875 GLU A OE2 1 ATOM 7070 N N . ARG A 1 876 ? 24.418 70.956 6.875 1.00 12.97 ? 876 ARG A N 1 ATOM 7071 C CA . ARG A 1 876 ? 25.301 69.787 7.085 1.00 13.60 ? 876 ARG A CA 1 ATOM 7072 C C . ARG A 1 876 ? 26.572 70.126 7.883 1.00 15.39 ? 876 ARG A C 1 ATOM 7073 O O . ARG A 1 876 ? 27.538 69.341 7.885 1.00 17.47 ? 876 ARG A O 1 ATOM 7074 C CB . ARG A 1 876 ? 25.670 69.099 5.761 1.00 13.72 ? 876 ARG A CB 1 ATOM 7075 C CG . ARG A 1 876 ? 24.437 68.576 5.018 1.00 11.87 ? 876 ARG A CG 1 ATOM 7076 C CD . ARG A 1 876 ? 23.637 67.622 5.906 1.00 12.44 ? 876 ARG A CD 1 ATOM 7077 N NE . ARG A 1 876 ? 22.544 66.907 5.215 1.00 11.87 ? 876 ARG A NE 1 ATOM 7078 C CZ . ARG A 1 876 ? 21.347 67.444 4.908 1.00 12.55 ? 876 ARG A CZ 1 ATOM 7079 N NH1 . ARG A 1 876 ? 21.099 68.736 5.183 1.00 11.91 ? 876 ARG A NH1 1 ATOM 7080 N NH2 . ARG A 1 876 ? 20.383 66.658 4.400 1.00 12.13 ? 876 ARG A NH2 1 ATOM 7081 N N . GLY A 1 877 ? 26.564 71.277 8.520 1.00 17.39 ? 877 GLY A N 1 ATOM 7082 C CA . GLY A 1 877 ? 27.734 71.633 9.346 1.00 17.58 ? 877 GLY A CA 1 ATOM 7083 C C . GLY A 1 877 ? 28.687 72.688 8.840 1.00 16.63 ? 877 GLY A C 1 ATOM 7084 O O . GLY A 1 877 ? 29.474 73.240 9.646 1.00 19.32 ? 877 GLY A O 1 ATOM 7085 N N . LEU A 1 878 ? 28.606 73.058 7.563 1.00 15.10 ? 878 LEU A N 1 ATOM 7086 C CA . LEU A 1 878 ? 29.546 74.060 7.047 1.00 16.05 ? 878 LEU A CA 1 ATOM 7087 C C . LEU A 1 878 ? 29.271 75.486 7.545 1.00 15.27 ? 878 LEU A C 1 ATOM 7088 O O . LEU A 1 878 ? 30.233 76.253 7.789 1.00 16.75 ? 878 LEU A O 1 ATOM 7089 C CB . LEU A 1 878 ? 29.535 73.982 5.510 1.00 13.27 ? 878 LEU A CB 1 ATOM 7090 C CG . LEU A 1 878 ? 30.324 75.052 4.762 1.00 13.39 ? 878 LEU A CG 1 ATOM 7091 C CD1 . LEU A 1 878 ? 31.831 75.026 5.218 1.00 12.58 ? 878 LEU A CD1 1 ATOM 7092 C CD2 . LEU A 1 878 ? 30.207 74.788 3.237 1.00 15.13 ? 878 LEU A CD2 1 ATOM 7093 N N . GLY A 1 879 ? 27.983 75.843 7.698 1.00 15.81 ? 879 GLY A N 1 ATOM 7094 C CA . GLY A 1 879 ? 27.629 77.152 8.228 1.00 17.99 ? 879 GLY A CA 1 ATOM 7095 C C . GLY A 1 879 ? 27.859 78.347 7.314 1.00 19.86 ? 879 GLY A C 1 ATOM 7096 O O . GLY A 1 879 ? 28.039 79.465 7.766 1.00 21.14 ? 879 GLY A O 1 ATOM 7097 N N . GLN A 1 880 ? 27.904 78.103 6.013 1.00 16.78 ? 880 GLN A N 1 ATOM 7098 C CA . GLN A 1 880 ? 28.008 79.205 5.066 1.00 14.99 ? 880 GLN A CA 1 ATOM 7099 C C . GLN A 1 880 ? 27.517 78.658 3.724 1.00 14.73 ? 880 GLN A C 1 ATOM 7100 O O . GLN A 1 880 ? 27.444 77.429 3.552 1.00 16.17 ? 880 GLN A O 1 ATOM 7101 C CB . GLN A 1 880 ? 29.461 79.719 4.928 1.00 14.28 ? 880 GLN A CB 1 ATOM 7102 C CG . GLN A 1 880 ? 30.494 78.671 4.407 1.00 16.31 ? 880 GLN A CG 1 ATOM 7103 C CD . GLN A 1 880 ? 31.760 79.334 3.812 1.00 15.39 ? 880 GLN A CD 1 ATOM 7104 O OE1 . GLN A 1 880 ? 31.835 79.600 2.606 1.00 20.00 ? 880 GLN A OE1 1 ATOM 7105 N NE2 . GLN A 1 880 ? 32.706 79.586 4.633 1.00 12.77 ? 880 GLN A NE2 1 ATOM 7106 N N . GLY A 1 881 ? 27.195 79.559 2.804 1.00 17.39 ? 881 GLY A N 1 ATOM 7107 C CA . GLY A 1 881 ? 26.872 79.166 1.433 1.00 18.12 ? 881 GLY A CA 1 ATOM 7108 C C . GLY A 1 881 ? 28.184 79.089 0.626 1.00 17.54 ? 881 GLY A C 1 ATOM 7109 O O . GLY A 1 881 ? 29.313 78.920 1.185 1.00 18.05 ? 881 GLY A O 1 ATOM 7110 N N . VAL A 1 882 ? 28.036 79.198 -0.691 1.00 14.53 ? 882 VAL A N 1 ATOM 7111 C CA . VAL A 1 882 ? 29.207 79.141 -1.569 1.00 12.38 ? 882 VAL A CA 1 ATOM 7112 C C . VAL A 1 882 ? 29.135 80.457 -2.335 1.00 12.02 ? 882 VAL A C 1 ATOM 7113 O O . VAL A 1 882 ? 28.400 80.628 -3.310 1.00 12.92 ? 882 VAL A O 1 ATOM 7114 C CB . VAL A 1 882 ? 29.128 77.940 -2.484 1.00 13.08 ? 882 VAL A CB 1 ATOM 7115 C CG1 . VAL A 1 882 ? 30.227 77.975 -3.513 1.00 13.33 ? 882 VAL A CG1 1 ATOM 7116 C CG2 . VAL A 1 882 ? 29.272 76.680 -1.635 1.00 14.38 ? 882 VAL A CG2 1 ATOM 7117 N N . LEU A 1 883 ? 29.924 81.419 -1.844 1.00 12.99 ? 883 LEU A N 1 ATOM 7118 C CA . LEU A 1 883 ? 29.911 82.783 -2.436 1.00 14.52 ? 883 LEU A CA 1 ATOM 7119 C C . LEU A 1 883 ? 31.330 83.278 -2.753 1.00 17.23 ? 883 LEU A C 1 ATOM 7120 O O . LEU A 1 883 ? 31.532 84.490 -2.933 1.00 20.22 ? 883 LEU A O 1 ATOM 7121 C CB . LEU A 1 883 ? 29.226 83.794 -1.461 1.00 15.92 ? 883 LEU A CB 1 ATOM 7122 C CG . LEU A 1 883 ? 27.741 83.516 -1.201 1.00 14.33 ? 883 LEU A CG 1 ATOM 7123 C CD1 . LEU A 1 883 ? 27.157 84.500 -0.124 1.00 17.53 ? 883 LEU A CD1 1 ATOM 7124 C CD2 . LEU A 1 883 ? 26.976 83.720 -2.544 1.00 16.98 ? 883 LEU A CD2 1 ATOM 7125 N N . ASP A 1 884 ? 32.305 82.375 -2.805 1.00 12.44 ? 884 ASP A N 1 ATOM 7126 C CA . ASP A 1 884 ? 33.722 82.655 -3.057 1.00 11.50 ? 884 ASP A CA 1 ATOM 7127 C C . ASP A 1 884 ? 34.200 82.177 -4.426 1.00 11.49 ? 884 ASP A C 1 ATOM 7128 O O . ASP A 1 884 ? 35.386 81.922 -4.631 1.00 13.26 ? 884 ASP A O 1 ATOM 7129 C CB . ASP A 1 884 ? 34.597 82.029 -1.944 1.00 14.29 ? 884 ASP A CB 1 ATOM 7130 C CG . ASP A 1 884 ? 34.374 80.488 -1.766 1.00 15.10 ? 884 ASP A CG 1 ATOM 7131 O OD1 . ASP A 1 884 ? 35.087 79.938 -0.872 1.00 17.43 ? 884 ASP A OD1 1 ATOM 7132 O OD2 . ASP A 1 884 ? 33.535 79.854 -2.474 1.00 13.61 ? 884 ASP A OD2 1 ATOM 7133 N N . ASN A 1 885 ? 33.260 82.147 -5.374 1.00 11.24 ? 885 ASN A N 1 ATOM 7134 C CA . ASN A 1 885 ? 33.583 81.761 -6.734 1.00 11.91 ? 885 ASN A CA 1 ATOM 7135 C C . ASN A 1 885 ? 34.649 82.630 -7.347 1.00 12.47 ? 885 ASN A C 1 ATOM 7136 O O . ASN A 1 885 ? 34.783 83.823 -7.034 1.00 13.22 ? 885 ASN A O 1 ATOM 7137 C CB . ASN A 1 885 ? 32.326 81.884 -7.623 1.00 10.74 ? 885 ASN A CB 1 ATOM 7138 C CG . ASN A 1 885 ? 31.154 81.168 -7.041 1.00 11.77 ? 885 ASN A CG 1 ATOM 7139 O OD1 . ASN A 1 885 ? 30.831 80.010 -7.468 1.00 14.22 ? 885 ASN A OD1 1 ATOM 7140 N ND2 . ASN A 1 885 ? 30.472 81.786 -6.126 1.00 11.14 ? 885 ASN A ND2 1 ATOM 7141 N N . LYS A 1 886 ? 35.444 82.040 -8.222 1.00 11.57 ? 886 LYS A N 1 ATOM 7142 C CA . LYS A 1 886 ? 36.445 82.789 -8.967 1.00 13.84 ? 886 LYS A CA 1 ATOM 7143 C C . LYS A 1 886 ? 36.516 82.209 -10.374 1.00 11.65 ? 886 LYS A C 1 ATOM 7144 O O . LYS A 1 886 ? 36.146 81.045 -10.624 1.00 12.47 ? 886 LYS A O 1 ATOM 7145 C CB . LYS A 1 886 ? 37.795 82.723 -8.236 1.00 18.89 ? 886 LYS A CB 1 ATOM 7146 C CG . LYS A 1 886 ? 38.342 81.323 -8.073 1.00 17.90 ? 886 LYS A CG 1 ATOM 7147 C CD . LYS A 1 886 ? 39.383 81.143 -6.904 1.00 22.90 ? 886 LYS A CD 1 ATOM 7148 C CE . LYS A 1 886 ? 40.711 81.656 -7.392 1.00 20.88 ? 886 LYS A CE 1 ATOM 7149 N NZ . LYS A 1 886 ? 41.888 81.749 -6.477 1.00 21.94 ? 886 LYS A NZ 1 ATOM 7150 N N . PRO A 1 887 ? 37.015 82.972 -11.337 1.00 10.23 ? 887 PRO A N 1 ATOM 7151 C CA . PRO A 1 887 ? 37.120 82.495 -12.711 1.00 9.98 ? 887 PRO A CA 1 ATOM 7152 C C . PRO A 1 887 ? 37.898 81.217 -12.800 1.00 10.18 ? 887 PRO A C 1 ATOM 7153 O O . PRO A 1 887 ? 38.965 81.088 -12.185 1.00 10.93 ? 887 PRO A O 1 ATOM 7154 C CB . PRO A 1 887 ? 37.868 83.638 -13.424 1.00 12.20 ? 887 PRO A CB 1 ATOM 7155 C CG . PRO A 1 887 ? 37.357 84.885 -12.623 1.00 12.55 ? 887 PRO A CG 1 ATOM 7156 C CD . PRO A 1 887 ? 37.372 84.413 -11.214 1.00 12.59 ? 887 PRO A CD 1 ATOM 7157 N N . VAL A 1 888 ? 37.385 80.249 -13.556 1.00 8.87 ? 888 VAL A N 1 ATOM 7158 C CA . VAL A 1 888 ? 38.071 78.968 -13.775 1.00 8.66 ? 888 VAL A CA 1 ATOM 7159 C C . VAL A 1 888 ? 38.011 78.610 -15.233 1.00 8.50 ? 888 VAL A C 1 ATOM 7160 O O . VAL A 1 888 ? 36.963 78.859 -15.902 1.00 9.76 ? 888 VAL A O 1 ATOM 7161 C CB . VAL A 1 888 ? 37.446 77.819 -12.872 1.00 9.86 ? 888 VAL A CB 1 ATOM 7162 C CG1 . VAL A 1 888 ? 35.901 77.718 -13.070 1.00 10.12 ? 888 VAL A CG1 1 ATOM 7163 C CG2 . VAL A 1 888 ? 38.121 76.507 -13.137 1.00 10.33 ? 888 VAL A CG2 1 ATOM 7164 N N . LEU A 1 889 ? 39.072 78.032 -15.779 1.00 7.38 ? 889 LEU A N 1 ATOM 7165 C CA . LEU A 1 889 ? 39.081 77.561 -17.151 1.00 8.57 ? 889 LEU A CA 1 ATOM 7166 C C . LEU A 1 889 ? 38.881 76.036 -17.173 1.00 8.39 ? 889 LEU A C 1 ATOM 7167 O O . LEU A 1 889 ? 39.775 75.251 -16.866 1.00 10.82 ? 889 LEU A O 1 ATOM 7168 C CB . LEU A 1 889 ? 40.419 77.915 -17.819 1.00 9.76 ? 889 LEU A CB 1 ATOM 7169 C CG . LEU A 1 889 ? 40.425 77.490 -19.325 1.00 10.15 ? 889 LEU A CG 1 ATOM 7170 C CD1 . LEU A 1 889 ? 39.521 78.452 -20.160 1.00 12.19 ? 889 LEU A CD1 1 ATOM 7171 C CD2 . LEU A 1 889 ? 41.880 77.528 -19.833 1.00 15.18 ? 889 LEU A CD2 1 ATOM 7172 N N . HIS A 1 890 ? 37.663 75.619 -17.490 1.00 7.20 ? 890 HIS A N 1 ATOM 7173 C CA . HIS A 1 890 ? 37.337 74.184 -17.632 1.00 7.37 ? 890 HIS A CA 1 ATOM 7174 C C . HIS A 1 890 ? 37.718 73.718 -19.009 1.00 7.55 ? 890 HIS A C 1 ATOM 7175 O O . HIS A 1 890 ? 37.490 74.449 -20.016 1.00 9.17 ? 890 HIS A O 1 ATOM 7176 C CB . HIS A 1 890 ? 35.827 73.943 -17.413 1.00 7.89 ? 890 HIS A CB 1 ATOM 7177 C CG . HIS A 1 890 ? 35.402 74.120 -16.006 1.00 8.57 ? 890 HIS A CG 1 ATOM 7178 N ND1 . HIS A 1 890 ? 36.220 73.775 -14.928 1.00 11.16 ? 890 HIS A ND1 1 ATOM 7179 C CD2 . HIS A 1 890 ? 34.229 74.539 -15.485 1.00 9.14 ? 890 HIS A CD2 1 ATOM 7180 C CE1 . HIS A 1 890 ? 35.541 73.979 -13.817 1.00 11.04 ? 890 HIS A CE1 1 ATOM 7181 N NE2 . HIS A 1 890 ? 34.332 74.431 -14.120 1.00 9.42 ? 890 HIS A NE2 1 ATOM 7182 N N . ILE A 1 891 ? 38.254 72.509 -19.125 1.00 7.38 ? 891 ILE A N 1 ATOM 7183 C CA . ILE A 1 891 ? 38.658 71.973 -20.420 1.00 6.46 ? 891 ILE A CA 1 ATOM 7184 C C . ILE A 1 891 ? 38.008 70.615 -20.703 1.00 6.93 ? 891 ILE A C 1 ATOM 7185 O O . ILE A 1 891 ? 37.726 69.843 -19.739 1.00 7.43 ? 891 ILE A O 1 ATOM 7186 C CB . ILE A 1 891 ? 40.197 71.919 -20.547 1.00 7.91 ? 891 ILE A CB 1 ATOM 7187 C CG1 . ILE A 1 891 ? 40.785 70.896 -19.561 1.00 9.05 ? 891 ILE A CG1 1 ATOM 7188 C CG2 . ILE A 1 891 ? 40.750 73.373 -20.334 1.00 10.66 ? 891 ILE A CG2 1 ATOM 7189 C CD1 . ILE A 1 891 ? 42.322 70.757 -19.791 1.00 9.93 ? 891 ILE A CD1 1 ATOM 7190 N N . TYR A 1 892 ? 37.780 70.325 -21.962 1.00 7.12 ? 892 TYR A N 1 ATOM 7191 C CA . TYR A 1 892 ? 37.100 69.106 -22.417 1.00 5.97 ? 892 TYR A CA 1 ATOM 7192 C C . TYR A 1 892 ? 37.517 68.684 -23.769 1.00 6.90 ? 892 TYR A C 1 ATOM 7193 O O . TYR A 1 892 ? 38.125 69.456 -24.538 1.00 8.13 ? 892 TYR A O 1 ATOM 7194 C CB . TYR A 1 892 ? 35.558 69.336 -22.518 1.00 7.33 ? 892 TYR A CB 1 ATOM 7195 C CG . TYR A 1 892 ? 34.898 70.007 -21.361 1.00 6.51 ? 892 TYR A CG 1 ATOM 7196 C CD1 . TYR A 1 892 ? 34.861 71.397 -21.235 1.00 7.52 ? 892 TYR A CD1 1 ATOM 7197 C CD2 . TYR A 1 892 ? 34.323 69.231 -20.329 1.00 7.77 ? 892 TYR A CD2 1 ATOM 7198 C CE1 . TYR A 1 892 ? 34.257 71.988 -20.151 1.00 8.24 ? 892 TYR A CE1 1 ATOM 7199 C CE2 . TYR A 1 892 ? 33.747 69.798 -19.239 1.00 7.73 ? 892 TYR A CE2 1 ATOM 7200 C CZ . TYR A 1 892 ? 33.715 71.191 -19.141 1.00 7.37 ? 892 TYR A CZ 1 ATOM 7201 O OH . TYR A 1 892 ? 33.112 71.742 -18.034 1.00 8.92 ? 892 TYR A OH 1 ATOM 7202 N N . ARG A 1 893 ? 37.224 67.407 -24.096 1.00 7.16 ? 893 ARG A N 1 ATOM 7203 C CA . ARG A 1 893 ? 37.334 66.962 -25.505 1.00 7.90 ? 893 ARG A CA 1 ATOM 7204 C C . ARG A 1 893 ? 35.958 66.328 -25.788 1.00 8.02 ? 893 ARG A C 1 ATOM 7205 O O . ARG A 1 893 ? 35.349 65.711 -24.937 1.00 9.36 ? 893 ARG A O 1 ATOM 7206 C CB . ARG A 1 893 ? 38.404 65.908 -25.741 1.00 7.75 ? 893 ARG A CB 1 ATOM 7207 C CG . ARG A 1 893 ? 39.843 66.403 -25.585 1.00 9.12 ? 893 ARG A CG 1 ATOM 7208 C CD . ARG A 1 893 ? 40.284 67.420 -26.665 1.00 9.02 ? 893 ARG A CD 1 ATOM 7209 N NE . ARG A 1 893 ? 40.335 66.857 -28.025 1.00 10.17 ? 893 ARG A NE 1 ATOM 7210 C CZ . ARG A 1 893 ? 41.271 66.033 -28.490 1.00 8.81 ? 893 ARG A CZ 1 ATOM 7211 N NH1 . ARG A 1 893 ? 42.291 65.602 -27.727 1.00 11.50 ? 893 ARG A NH1 1 ATOM 7212 N NH2 . ARG A 1 893 ? 41.233 65.590 -29.756 1.00 12.93 ? 893 ARG A NH2 1 ATOM 7213 N N . LEU A 1 894 ? 35.477 66.550 -27.026 1.00 8.21 ? 894 LEU A N 1 ATOM 7214 C CA . LEU A 1 894 ? 34.133 66.082 -27.468 1.00 9.94 ? 894 LEU A CA 1 ATOM 7215 C C . LEU A 1 894 ? 34.324 65.134 -28.632 1.00 9.35 ? 894 LEU A C 1 ATOM 7216 O O . LEU A 1 894 ? 34.764 65.556 -29.715 1.00 10.21 ? 894 LEU A O 1 ATOM 7217 C CB . LEU A 1 894 ? 33.287 67.295 -27.876 1.00 10.92 ? 894 LEU A CB 1 ATOM 7218 C CG . LEU A 1 894 ? 31.839 66.889 -28.277 1.00 11.67 ? 894 LEU A CG 1 ATOM 7219 C CD1 . LEU A 1 894 ? 31.088 66.334 -27.104 1.00 14.86 ? 894 LEU A CD1 1 ATOM 7220 C CD2 . LEU A 1 894 ? 31.111 68.134 -28.805 1.00 14.01 ? 894 LEU A CD2 1 ATOM 7221 N N . VAL A 1 895 ? 34.034 63.841 -28.404 1.00 9.42 ? 895 VAL A N 1 ATOM 7222 C CA . VAL A 1 895 ? 34.263 62.803 -29.384 1.00 9.86 ? 895 VAL A CA 1 ATOM 7223 C C . VAL A 1 895 ? 32.957 62.157 -29.854 1.00 11.27 ? 895 VAL A C 1 ATOM 7224 O O . VAL A 1 895 ? 32.264 61.437 -29.093 1.00 10.58 ? 895 VAL A O 1 ATOM 7225 C CB . VAL A 1 895 ? 35.163 61.704 -28.732 1.00 10.57 ? 895 VAL A CB 1 ATOM 7226 C CG1 . VAL A 1 895 ? 35.494 60.674 -29.770 1.00 13.80 ? 895 VAL A CG1 1 ATOM 7227 C CG2 . VAL A 1 895 ? 36.427 62.350 -28.130 1.00 12.98 ? 895 VAL A CG2 1 ATOM 7228 N N . LEU A 1 896 ? 32.611 62.431 -31.112 1.00 11.05 ? 896 LEU A N 1 ATOM 7229 C CA . LEU A 1 896 ? 31.425 61.810 -31.755 1.00 10.89 ? 896 LEU A CA 1 ATOM 7230 C C . LEU A 1 896 ? 32.014 60.688 -32.606 1.00 12.22 ? 896 LEU A C 1 ATOM 7231 O O . LEU A 1 896 ? 32.972 60.864 -33.346 1.00 12.62 ? 896 LEU A O 1 ATOM 7232 C CB . LEU A 1 896 ? 30.697 62.818 -32.658 1.00 11.36 ? 896 LEU A CB 1 ATOM 7233 C CG . LEU A 1 896 ? 29.575 62.123 -33.470 1.00 12.50 ? 896 LEU A CG 1 ATOM 7234 C CD1 . LEU A 1 896 ? 28.429 61.862 -32.585 1.00 15.00 ? 896 LEU A CD1 1 ATOM 7235 C CD2 . LEU A 1 896 ? 29.100 63.110 -34.589 1.00 15.35 ? 896 LEU A CD2 1 ATOM 7236 N N . GLU A 1 897 ? 31.446 59.481 -32.447 1.00 11.76 ? 897 GLU A N 1 ATOM 7237 C CA . GLU A 1 897 ? 31.962 58.322 -33.190 1.00 12.33 ? 897 GLU A CA 1 ATOM 7238 C C . GLU A 1 897 ? 30.849 57.351 -33.587 1.00 11.94 ? 897 GLU A C 1 ATOM 7239 O O . GLU A 1 897 ? 29.819 57.271 -32.918 1.00 12.67 ? 897 GLU A O 1 ATOM 7240 C CB . GLU A 1 897 ? 32.924 57.528 -32.316 1.00 15.79 ? 897 GLU A CB 1 ATOM 7241 C CG . GLU A 1 897 ? 34.004 58.250 -31.546 1.00 20.44 ? 897 GLU A CG 1 ATOM 7242 C CD . GLU A 1 897 ? 34.674 57.329 -30.435 1.00 14.08 ? 897 GLU A CD 1 ATOM 7243 O OE1 . GLU A 1 897 ? 34.031 57.069 -29.356 1.00 20.85 ? 897 GLU A OE1 1 ATOM 7244 O OE2 . GLU A 1 897 ? 35.838 56.997 -30.731 1.00 23.59 ? 897 GLU A OE2 1 ATOM 7245 N N A LYS A 1 898 ? 31.141 56.574 -34.636 0.50 12.42 ? 898 LYS A N 1 ATOM 7246 N N B LYS A 1 898 ? 31.141 56.574 -34.636 0.50 12.56 ? 898 LYS A N 1 ATOM 7247 C CA A LYS A 1 898 ? 30.246 55.474 -35.046 0.50 13.41 ? 898 LYS A CA 1 ATOM 7248 C CA B LYS A 1 898 ? 30.246 55.474 -35.046 0.50 13.54 ? 898 LYS A CA 1 ATOM 7249 C C A LYS A 1 898 ? 30.726 54.270 -34.242 0.50 15.34 ? 898 LYS A C 1 ATOM 7250 C C B LYS A 1 898 ? 30.726 54.270 -34.242 0.50 15.45 ? 898 LYS A C 1 ATOM 7251 O O A LYS A 1 898 ? 31.931 53.980 -34.177 0.50 20.39 ? 898 LYS A O 1 ATOM 7252 O O B LYS A 1 898 ? 31.931 53.980 -34.177 0.50 20.49 ? 898 LYS A O 1 ATOM 7253 C CB A LYS A 1 898 ? 30.425 55.201 -36.524 0.50 15.91 ? 898 LYS A CB 1 ATOM 7254 C CB B LYS A 1 898 ? 30.425 55.201 -36.524 0.50 16.20 ? 898 LYS A CB 1 ATOM 7255 C CG A LYS A 1 898 ? 29.949 56.319 -37.416 0.50 20.06 ? 898 LYS A CG 1 ATOM 7256 C CG B LYS A 1 898 ? 29.949 56.319 -37.416 0.50 20.29 ? 898 LYS A CG 1 ATOM 7257 C CD A LYS A 1 898 ? 28.513 56.827 -37.113 0.50 25.76 ? 898 LYS A CD 1 ATOM 7258 C CD B LYS A 1 898 ? 28.513 56.827 -37.113 0.50 25.78 ? 898 LYS A CD 1 ATOM 7259 C CE A LYS A 1 898 ? 27.388 55.730 -37.111 0.50 28.76 ? 898 LYS A CE 1 ATOM 7260 C CE B LYS A 1 898 ? 27.372 55.753 -37.225 0.50 28.76 ? 898 LYS A CE 1 ATOM 7261 N NZ A LYS A 1 898 ? 27.155 55.148 -38.458 0.50 33.16 ? 898 LYS A NZ 1 ATOM 7262 N NZ B LYS A 1 898 ? 27.829 54.500 -37.880 0.50 32.96 ? 898 LYS A NZ 1 ATOM 7263 N N . VAL A 1 899 ? 29.787 53.570 -33.618 1.00 13.74 ? 899 VAL A N 1 ATOM 7264 C CA . VAL A 1 899 ? 30.114 52.424 -32.800 1.00 14.29 ? 899 VAL A CA 1 ATOM 7265 C C . VAL A 1 899 ? 29.390 51.139 -33.225 1.00 15.60 ? 899 VAL A C 1 ATOM 7266 O O . VAL A 1 899 ? 29.434 50.117 -32.557 1.00 13.67 ? 899 VAL A O 1 ATOM 7267 C CB . VAL A 1 899 ? 29.821 52.712 -31.304 1.00 13.93 ? 899 VAL A CB 1 ATOM 7268 C CG1 . VAL A 1 899 ? 30.846 53.758 -30.761 1.00 17.30 ? 899 VAL A CG1 1 ATOM 7269 C CG2 . VAL A 1 899 ? 28.416 53.200 -31.124 1.00 13.68 ? 899 VAL A CG2 1 ATOM 7270 N N . ASN A 1 900 ? 28.736 51.196 -34.377 1.00 15.02 ? 900 ASN A N 1 ATOM 7271 C CA . ASN A 1 900 ? 27.995 50.004 -34.840 1.00 16.08 ? 900 ASN A CA 1 ATOM 7272 C C . ASN A 1 900 ? 28.906 48.767 -35.076 1.00 14.26 ? 900 ASN A C 1 ATOM 7273 O O . ASN A 1 900 ? 28.411 47.630 -35.046 1.00 19.44 ? 900 ASN A O 1 ATOM 7274 C CB . ASN A 1 900 ? 27.220 50.336 -36.157 1.00 16.89 ? 900 ASN A CB 1 ATOM 7275 C CG . ASN A 1 900 ? 28.107 50.880 -37.221 1.00 19.87 ? 900 ASN A CG 1 ATOM 7276 O OD1 . ASN A 1 900 ? 28.740 51.937 -37.093 1.00 26.68 ? 900 ASN A OD1 1 ATOM 7277 N ND2 . ASN A 1 900 ? 28.209 50.122 -38.328 1.00 24.17 ? 900 ASN A ND2 1 ATOM 7278 N N . ASN A 1 901 ? 30.179 48.969 -35.330 1.00 12.34 ? 901 ASN A N 1 ATOM 7279 C CA . ASN A 1 901 ? 31.128 47.876 -35.546 1.00 14.98 ? 901 ASN A CA 1 ATOM 7280 C C . ASN A 1 901 ? 31.888 47.474 -34.288 1.00 14.34 ? 901 ASN A C 1 ATOM 7281 O O . ASN A 1 901 ? 32.656 46.536 -34.345 1.00 15.68 ? 901 ASN A O 1 ATOM 7282 C CB . ASN A 1 901 ? 32.149 48.289 -36.624 1.00 17.97 ? 901 ASN A CB 1 ATOM 7283 C CG . ASN A 1 901 ? 31.573 48.273 -38.005 1.00 24.68 ? 901 ASN A CG 1 ATOM 7284 O OD1 . ASN A 1 901 ? 31.930 49.125 -38.832 1.00 29.94 ? 901 ASN A OD1 1 ATOM 7285 N ND2 . ASN A 1 901 ? 30.711 47.311 -38.289 1.00 23.90 ? 901 ASN A ND2 1 ATOM 7286 N N . CYS A 1 902 ? 31.684 48.186 -33.194 1.00 14.31 ? 902 CYS A N 1 ATOM 7287 C CA . CYS A 1 902 ? 32.429 47.877 -31.977 1.00 15.32 ? 902 CYS A CA 1 ATOM 7288 C C . CYS A 1 902 ? 31.889 46.677 -31.214 1.00 12.62 ? 902 CYS A C 1 ATOM 7289 O O . CYS A 1 902 ? 30.655 46.523 -31.070 1.00 15.85 ? 902 CYS A O 1 ATOM 7290 C CB . CYS A 1 902 ? 32.391 49.046 -31.012 1.00 15.39 ? 902 CYS A CB 1 ATOM 7291 S SG . CYS A 1 902 ? 33.144 50.580 -31.618 1.00 18.17 ? 902 CYS A SG 1 ATOM 7292 N N . VAL A 1 903 ? 32.813 45.888 -30.678 1.00 12.48 ? 903 VAL A N 1 ATOM 7293 C CA . VAL A 1 903 ? 32.393 44.747 -29.813 1.00 13.45 ? 903 VAL A CA 1 ATOM 7294 C C . VAL A 1 903 ? 32.110 45.321 -28.415 1.00 14.27 ? 903 VAL A C 1 ATOM 7295 O O . VAL A 1 903 ? 33.028 45.691 -27.658 1.00 15.14 ? 903 VAL A O 1 ATOM 7296 C CB . VAL A 1 903 ? 33.487 43.683 -29.771 1.00 12.93 ? 903 VAL A CB 1 ATOM 7297 C CG1 . VAL A 1 903 ? 33.117 42.532 -28.782 1.00 14.89 ? 903 VAL A CG1 1 ATOM 7298 C CG2 . VAL A 1 903 ? 33.628 43.131 -31.196 1.00 15.34 ? 903 VAL A CG2 1 ATOM 7299 N N . ARG A 1 904 ? 30.856 45.458 -28.071 1.00 13.48 ? 904 ARG A N 1 ATOM 7300 C CA . ARG A 1 904 ? 30.484 46.053 -26.796 1.00 13.54 ? 904 ARG A CA 1 ATOM 7301 C C . ARG A 1 904 ? 29.920 45.002 -25.841 1.00 13.62 ? 904 ARG A C 1 ATOM 7302 O O . ARG A 1 904 ? 29.545 43.883 -26.253 1.00 13.67 ? 904 ARG A O 1 ATOM 7303 C CB . ARG A 1 904 ? 29.388 47.102 -27.026 1.00 13.80 ? 904 ARG A CB 1 ATOM 7304 C CG . ARG A 1 904 ? 29.950 48.337 -27.677 1.00 16.33 ? 904 ARG A CG 1 ATOM 7305 C CD . ARG A 1 904 ? 28.858 49.359 -27.924 1.00 20.63 ? 904 ARG A CD 1 ATOM 7306 N NE . ARG A 1 904 ? 28.152 49.012 -29.136 1.00 18.71 ? 904 ARG A NE 1 ATOM 7307 C CZ . ARG A 1 904 ? 27.202 49.787 -29.649 1.00 19.51 ? 904 ARG A CZ 1 ATOM 7308 N NH1 . ARG A 1 904 ? 26.850 50.934 -29.061 1.00 20.18 ? 904 ARG A NH1 1 ATOM 7309 N NH2 . ARG A 1 904 ? 26.596 49.383 -30.757 1.00 20.11 ? 904 ARG A NH2 1 ATOM 7310 N N . PRO A 1 905 ? 29.877 45.324 -24.538 1.00 11.25 ? 905 PRO A N 1 ATOM 7311 C CA . PRO A 1 905 ? 29.303 44.378 -23.573 1.00 12.41 ? 905 PRO A CA 1 ATOM 7312 C C . PRO A 1 905 ? 27.815 44.162 -23.908 1.00 12.30 ? 905 PRO A C 1 ATOM 7313 O O . PRO A 1 905 ? 27.175 44.987 -24.588 1.00 12.98 ? 905 PRO A O 1 ATOM 7314 C CB . PRO A 1 905 ? 29.406 45.134 -22.236 1.00 12.36 ? 905 PRO A CB 1 ATOM 7315 C CG . PRO A 1 905 ? 30.570 46.098 -22.453 1.00 11.73 ? 905 PRO A CG 1 ATOM 7316 C CD . PRO A 1 905 ? 30.373 46.570 -23.883 1.00 11.51 ? 905 PRO A CD 1 ATOM 7317 N N . SER A 1 906 ? 27.259 43.049 -23.433 1.00 12.99 ? 906 SER A N 1 ATOM 7318 C CA . SER A 1 906 ? 25.830 42.799 -23.616 1.00 14.92 ? 906 SER A CA 1 ATOM 7319 C C . SER A 1 906 ? 24.991 43.788 -22.852 1.00 14.88 ? 906 SER A C 1 ATOM 7320 O O . SER A 1 906 ? 25.498 44.543 -21.987 1.00 14.81 ? 906 SER A O 1 ATOM 7321 C CB . SER A 1 906 ? 25.499 41.404 -23.142 1.00 21.44 ? 906 SER A CB 1 ATOM 7322 O OG . SER A 1 906 ? 25.159 41.494 -21.789 1.00 24.76 ? 906 SER A OG 1 ATOM 7323 N N . LYS A 1 907 ? 23.696 43.819 -23.134 1.00 15.54 ? 907 LYS A N 1 ATOM 7324 C CA . LYS A 1 907 ? 22.820 44.769 -22.488 1.00 18.53 ? 907 LYS A CA 1 ATOM 7325 C C . LYS A 1 907 ? 22.743 44.571 -20.981 1.00 16.77 ? 907 LYS A C 1 ATOM 7326 O O . LYS A 1 907 ? 22.351 45.501 -20.281 1.00 22.11 ? 907 LYS A O 1 ATOM 7327 C CB . LYS A 1 907 ? 21.418 44.705 -23.133 1.00 23.96 ? 907 LYS A CB 1 ATOM 7328 C CG . LYS A 1 907 ? 20.640 43.451 -22.809 1.00 31.14 ? 907 LYS A CG 1 ATOM 7329 C CD . LYS A 1 907 ? 19.251 43.483 -23.495 1.00 37.16 ? 907 LYS A CD 1 ATOM 7330 C CE . LYS A 1 907 ? 18.171 44.080 -22.581 1.00 39.27 ? 907 LYS A CE 1 ATOM 7331 N NZ . LYS A 1 907 ? 17.821 43.160 -21.436 1.00 42.67 ? 907 LYS A NZ 1 ATOM 7332 N N . LEU A 1 908 ? 23.130 43.415 -20.468 1.00 15.14 ? 908 LEU A N 1 ATOM 7333 C CA . LEU A 1 908 ? 23.040 43.208 -19.021 1.00 17.06 ? 908 LEU A CA 1 ATOM 7334 C C . LEU A 1 908 ? 24.350 43.501 -18.277 1.00 15.10 ? 908 LEU A C 1 ATOM 7335 O O . LEU A 1 908 ? 24.401 43.424 -17.044 1.00 17.05 ? 908 LEU A O 1 ATOM 7336 C CB . LEU A 1 908 ? 22.586 41.767 -18.700 1.00 21.11 ? 908 LEU A CB 1 ATOM 7337 C CG . LEU A 1 908 ? 21.188 41.338 -19.209 1.00 22.97 ? 908 LEU A CG 1 ATOM 7338 C CD1 . LEU A 1 908 ? 20.918 39.882 -18.808 1.00 23.88 ? 908 LEU A CD1 1 ATOM 7339 C CD2 . LEU A 1 908 ? 20.080 42.257 -18.626 1.00 23.36 ? 908 LEU A CD2 1 ATOM 7340 N N . HIS A 1 909 ? 25.406 43.843 -19.010 1.00 14.18 ? 909 HIS A N 1 ATOM 7341 C CA . HIS A 1 909 ? 26.708 44.112 -18.358 1.00 12.25 ? 909 HIS A CA 1 ATOM 7342 C C . HIS A 1 909 ? 26.662 45.502 -17.705 1.00 12.60 ? 909 HIS A C 1 ATOM 7343 O O . HIS A 1 909 ? 26.232 46.453 -18.310 1.00 12.72 ? 909 HIS A O 1 ATOM 7344 C CB . HIS A 1 909 ? 27.788 44.043 -19.399 1.00 12.25 ? 909 HIS A CB 1 ATOM 7345 C CG . HIS A 1 909 ? 29.161 43.818 -18.843 1.00 10.23 ? 909 HIS A CG 1 ATOM 7346 N ND1 . HIS A 1 909 ? 29.849 44.792 -18.118 1.00 11.89 ? 909 HIS A ND1 1 ATOM 7347 C CD2 . HIS A 1 909 ? 29.974 42.741 -18.922 1.00 11.31 ? 909 HIS A CD2 1 ATOM 7348 C CE1 . HIS A 1 909 ? 31.034 44.300 -17.790 1.00 11.89 ? 909 HIS A CE1 1 ATOM 7349 N NE2 . HIS A 1 909 ? 31.139 43.059 -18.276 1.00 12.87 ? 909 HIS A NE2 1 ATOM 7350 N N . PRO A 1 910 ? 27.149 45.635 -16.492 1.00 9.81 ? 910 PRO A N 1 ATOM 7351 C CA . PRO A 1 910 ? 27.129 46.957 -15.796 1.00 9.57 ? 910 PRO A CA 1 ATOM 7352 C C . PRO A 1 910 ? 28.214 47.939 -16.197 1.00 7.82 ? 910 PRO A C 1 ATOM 7353 O O . PRO A 1 910 ? 28.171 49.047 -15.644 1.00 9.48 ? 910 PRO A O 1 ATOM 7354 C CB . PRO A 1 910 ? 27.201 46.626 -14.308 1.00 10.87 ? 910 PRO A CB 1 ATOM 7355 C CG . PRO A 1 910 ? 27.471 45.123 -14.218 1.00 12.89 ? 910 PRO A CG 1 ATOM 7356 C CD . PRO A 1 910 ? 27.565 44.525 -15.588 1.00 11.32 ? 910 PRO A CD 1 ATOM 7357 N N . ALA A 1 911 ? 29.175 47.559 -17.015 1.00 8.90 ? 911 ALA A N 1 ATOM 7358 C CA . ALA A 1 911 ? 30.260 48.492 -17.412 1.00 9.21 ? 911 ALA A CA 1 ATOM 7359 C C . ALA A 1 911 ? 30.150 48.949 -18.821 1.00 10.39 ? 911 ALA A C 1 ATOM 7360 O O . ALA A 1 911 ? 29.423 48.336 -19.644 1.00 11.13 ? 911 ALA A O 1 ATOM 7361 C CB . ALA A 1 911 ? 31.617 47.812 -17.287 1.00 10.23 ? 911 ALA A CB 1 ATOM 7362 N N . GLY A 1 912 ? 30.903 49.991 -19.152 1.00 9.78 ? 912 GLY A N 1 ATOM 7363 C CA . GLY A 1 912 ? 31.107 50.446 -20.510 1.00 11.80 ? 912 GLY A CA 1 ATOM 7364 C C . GLY A 1 912 ? 32.605 50.715 -20.679 1.00 9.76 ? 912 GLY A C 1 ATOM 7365 O O . GLY A 1 912 ? 33.352 50.829 -19.663 1.00 9.97 ? 912 GLY A O 1 ATOM 7366 N N . TYR A 1 913 ? 33.076 50.865 -21.902 1.00 9.27 ? 913 TYR A N 1 ATOM 7367 C CA . TYR A 1 913 ? 34.498 51.076 -22.193 1.00 9.38 ? 913 TYR A CA 1 ATOM 7368 C C . TYR A 1 913 ? 34.662 52.111 -23.274 1.00 9.95 ? 913 TYR A C 1 ATOM 7369 O O . TYR A 1 913 ? 33.835 52.166 -24.216 1.00 10.83 ? 913 TYR A O 1 ATOM 7370 C CB . TYR A 1 913 ? 35.172 49.758 -22.672 1.00 9.24 ? 913 TYR A CB 1 ATOM 7371 C CG . TYR A 1 913 ? 35.121 48.695 -21.585 1.00 8.22 ? 913 TYR A CG 1 ATOM 7372 C CD1 . TYR A 1 913 ? 34.126 47.736 -21.584 1.00 9.49 ? 913 TYR A CD1 1 ATOM 7373 C CD2 . TYR A 1 913 ? 36.005 48.752 -20.519 1.00 9.61 ? 913 TYR A CD2 1 ATOM 7374 C CE1 . TYR A 1 913 ? 34.033 46.834 -20.493 1.00 11.22 ? 913 TYR A CE1 1 ATOM 7375 C CE2 . TYR A 1 913 ? 35.928 47.887 -19.451 1.00 9.16 ? 913 TYR A CE2 1 ATOM 7376 C CZ . TYR A 1 913 ? 34.937 46.926 -19.443 1.00 10.12 ? 913 TYR A CZ 1 ATOM 7377 O OH . TYR A 1 913 ? 34.831 46.051 -18.368 1.00 10.98 ? 913 TYR A OH 1 ATOM 7378 N N . LEU A 1 914 ? 35.744 52.862 -23.189 1.00 8.88 ? 914 LEU A N 1 ATOM 7379 C CA . LEU A 1 914 ? 36.041 53.865 -24.194 1.00 8.86 ? 914 LEU A CA 1 ATOM 7380 C C . LEU A 1 914 ? 36.618 53.260 -25.432 1.00 10.76 ? 914 LEU A C 1 ATOM 7381 O O . LEU A 1 914 ? 37.164 52.141 -25.443 1.00 10.20 ? 914 LEU A O 1 ATOM 7382 C CB . LEU A 1 914 ? 37.125 54.841 -23.630 1.00 9.58 ? 914 LEU A CB 1 ATOM 7383 C CG . LEU A 1 914 ? 36.687 55.739 -22.458 1.00 10.01 ? 914 LEU A CG 1 ATOM 7384 C CD1 . LEU A 1 914 ? 37.800 56.762 -22.175 1.00 11.30 ? 914 LEU A CD1 1 ATOM 7385 C CD2 . LEU A 1 914 ? 35.326 56.455 -22.749 1.00 9.47 ? 914 LEU A CD2 1 ATOM 7386 N N . THR A 1 915 ? 36.539 54.044 -26.512 1.00 11.09 ? 915 THR A N 1 ATOM 7387 C CA . THR A 1 915 ? 37.263 53.720 -27.731 1.00 10.10 ? 915 THR A CA 1 ATOM 7388 C C . THR A 1 915 ? 38.705 54.286 -27.618 1.00 10.72 ? 915 THR A C 1 ATOM 7389 O O . THR A 1 915 ? 39.022 55.122 -26.707 1.00 11.12 ? 915 THR A O 1 ATOM 7390 C CB . THR A 1 915 ? 36.631 54.441 -28.924 1.00 11.80 ? 915 THR A CB 1 ATOM 7391 O OG1 . THR A 1 915 ? 36.657 55.872 -28.631 1.00 14.27 ? 915 THR A OG1 1 ATOM 7392 C CG2 . THR A 1 915 ? 35.222 53.964 -29.248 1.00 13.80 ? 915 THR A CG2 1 ATOM 7393 N N A SER A 1 916 ? 39.609 53.886 -28.508 0.50 10.55 ? 916 SER A N 1 ATOM 7394 N N B SER A 1 916 ? 39.609 53.886 -28.508 0.50 12.31 ? 916 SER A N 1 ATOM 7395 C CA A SER A 1 916 ? 40.936 54.418 -28.556 0.50 10.14 ? 916 SER A CA 1 ATOM 7396 C CA B SER A 1 916 ? 40.936 54.418 -28.556 0.50 13.37 ? 916 SER A CA 1 ATOM 7397 C C A SER A 1 916 ? 40.939 55.943 -28.659 0.50 11.42 ? 916 SER A C 1 ATOM 7398 C C B SER A 1 916 ? 40.939 55.943 -28.659 0.50 13.04 ? 916 SER A C 1 ATOM 7399 O O A SER A 1 916 ? 41.665 56.629 -27.911 0.50 10.33 ? 916 SER A O 1 ATOM 7400 O O B SER A 1 916 ? 41.665 56.629 -27.911 0.50 11.37 ? 916 SER A O 1 ATOM 7401 C CB A SER A 1 916 ? 41.669 53.846 -29.799 0.50 10.75 ? 916 SER A CB 1 ATOM 7402 C CB B SER A 1 916 ? 41.669 53.846 -29.799 0.50 16.98 ? 916 SER A CB 1 ATOM 7403 O OG A SER A 1 916 ? 42.867 54.560 -30.031 0.50 11.93 ? 916 SER A OG 1 ATOM 7404 O OG B SER A 1 916 ? 42.112 52.528 -29.541 0.50 25.73 ? 916 SER A OG 1 ATOM 7405 N N . ALA A 1 917 ? 40.116 56.517 -29.523 1.00 10.29 ? 917 ALA A N 1 ATOM 7406 C CA . ALA A 1 917 ? 40.196 57.979 -29.690 1.00 10.88 ? 917 ALA A CA 1 ATOM 7407 C C . ALA A 1 917 ? 39.733 58.677 -28.415 1.00 9.95 ? 917 ALA A C 1 ATOM 7408 O O . ALA A 1 917 ? 40.272 59.753 -28.042 1.00 10.43 ? 917 ALA A O 1 ATOM 7409 C CB . ALA A 1 917 ? 39.312 58.450 -30.855 1.00 12.46 ? 917 ALA A CB 1 ATOM 7410 N N . ALA A 1 918 ? 38.717 58.130 -27.744 1.00 8.94 ? 918 ALA A N 1 ATOM 7411 C CA . ALA A 1 918 ? 38.246 58.808 -26.502 1.00 9.91 ? 918 ALA A CA 1 ATOM 7412 C C . ALA A 1 918 ? 39.284 58.687 -25.398 1.00 8.47 ? 918 ALA A C 1 ATOM 7413 O O . ALA A 1 918 ? 39.496 59.637 -24.620 1.00 9.16 ? 918 ALA A O 1 ATOM 7414 C CB . ALA A 1 918 ? 36.897 58.263 -26.076 1.00 10.40 ? 918 ALA A CB 1 ATOM 7415 N N . HIS A 1 919 ? 39.919 57.537 -25.271 1.00 8.53 ? 919 HIS A N 1 ATOM 7416 C CA . HIS A 1 919 ? 40.950 57.394 -24.257 1.00 7.99 ? 919 HIS A CA 1 ATOM 7417 C C . HIS A 1 919 ? 42.123 58.330 -24.534 1.00 8.83 ? 919 HIS A C 1 ATOM 7418 O O . HIS A 1 919 ? 42.626 59.001 -23.597 1.00 8.43 ? 919 HIS A O 1 ATOM 7419 C CB . HIS A 1 919 ? 41.411 55.914 -24.283 1.00 10.22 ? 919 HIS A CB 1 ATOM 7420 C CG . HIS A 1 919 ? 42.519 55.638 -23.323 1.00 10.89 ? 919 HIS A CG 1 ATOM 7421 N ND1 . HIS A 1 919 ? 43.773 55.227 -23.722 1.00 14.98 ? 919 HIS A ND1 1 ATOM 7422 C CD2 . HIS A 1 919 ? 42.555 55.759 -21.981 1.00 10.93 ? 919 HIS A CD2 1 ATOM 7423 C CE1 . HIS A 1 919 ? 44.556 55.110 -22.656 1.00 13.72 ? 919 HIS A CE1 1 ATOM 7424 N NE2 . HIS A 1 919 ? 43.857 55.423 -21.598 1.00 13.72 ? 919 HIS A NE2 1 ATOM 7425 N N . LYS A 1 920 ? 42.617 58.402 -25.765 1.00 9.24 ? 920 LYS A N 1 ATOM 7426 C CA . LYS A 1 920 ? 43.691 59.336 -26.073 1.00 9.67 ? 920 LYS A CA 1 ATOM 7427 C C . LYS A 1 920 ? 43.236 60.770 -25.804 1.00 8.03 ? 920 LYS A C 1 ATOM 7428 O O . LYS A 1 920 ? 44.024 61.603 -25.314 1.00 9.01 ? 920 LYS A O 1 ATOM 7429 C CB . LYS A 1 920 ? 44.161 59.198 -27.521 1.00 11.82 ? 920 LYS A CB 1 ATOM 7430 C CG . LYS A 1 920 ? 45.025 57.929 -27.642 1.00 14.93 ? 920 LYS A CG 1 ATOM 7431 C CD . LYS A 1 920 ? 45.816 57.891 -28.935 1.00 16.89 ? 920 LYS A CD 1 ATOM 7432 C CE . LYS A 1 920 ? 46.678 56.687 -29.029 1.00 15.95 ? 920 LYS A CE 1 ATOM 7433 N NZ . LYS A 1 920 ? 47.900 56.747 -28.134 1.00 16.54 ? 920 LYS A NZ 1 ATOM 7434 N N . ALA A 1 921 ? 41.973 61.108 -26.085 1.00 8.21 ? 921 ALA A N 1 ATOM 7435 C CA . ALA A 1 921 ? 41.510 62.467 -25.814 1.00 8.74 ? 921 ALA A CA 1 ATOM 7436 C C . ALA A 1 921 ? 41.538 62.716 -24.288 1.00 8.21 ? 921 ALA A C 1 ATOM 7437 O O . ALA A 1 921 ? 41.892 63.829 -23.838 1.00 8.72 ? 921 ALA A O 1 ATOM 7438 C CB . ALA A 1 921 ? 40.067 62.633 -26.377 1.00 8.60 ? 921 ALA A CB 1 ATOM 7439 N N . SER A 1 922 ? 41.153 61.717 -23.474 1.00 7.84 ? 922 SER A N 1 ATOM 7440 C CA . SER A 1 922 ? 41.247 61.910 -22.019 1.00 7.23 ? 922 SER A CA 1 ATOM 7441 C C . SER A 1 922 ? 42.716 62.120 -21.598 1.00 8.75 ? 922 SER A C 1 ATOM 7442 O O . SER A 1 922 ? 43.001 63.027 -20.804 1.00 9.09 ? 922 SER A O 1 ATOM 7443 C CB . SER A 1 922 ? 40.660 60.706 -21.320 1.00 7.91 ? 922 SER A CB 1 ATOM 7444 O OG . SER A 1 922 ? 40.821 60.859 -19.907 1.00 8.07 ? 922 SER A OG 1 ATOM 7445 N N . GLN A 1 923 ? 43.624 61.347 -22.152 1.00 8.50 ? 923 GLN A N 1 ATOM 7446 C CA . GLN A 1 923 ? 45.051 61.540 -21.811 1.00 8.55 ? 923 GLN A CA 1 ATOM 7447 C C . GLN A 1 923 ? 45.542 62.916 -22.255 1.00 8.42 ? 923 GLN A C 1 ATOM 7448 O O . GLN A 1 923 ? 46.423 63.496 -21.583 1.00 9.13 ? 923 GLN A O 1 ATOM 7449 C CB . GLN A 1 923 ? 45.895 60.438 -22.457 1.00 8.21 ? 923 GLN A CB 1 ATOM 7450 C CG . GLN A 1 923 ? 45.596 59.056 -21.918 1.00 8.18 ? 923 GLN A CG 1 ATOM 7451 C CD . GLN A 1 923 ? 46.549 58.024 -22.513 1.00 9.92 ? 923 GLN A CD 1 ATOM 7452 O OE1 . GLN A 1 923 ? 46.706 57.942 -23.753 1.00 11.59 ? 923 GLN A OE1 1 ATOM 7453 N NE2 . GLN A 1 923 ? 47.164 57.200 -21.661 1.00 9.94 ? 923 GLN A NE2 1 ATOM 7454 N N . SER A 1 924 ? 45.004 63.495 -23.335 1.00 8.48 ? 924 SER A N 1 ATOM 7455 C CA . SER A 1 924 ? 45.450 64.815 -23.787 1.00 9.08 ? 924 SER A CA 1 ATOM 7456 C C . SER A 1 924 ? 45.048 65.900 -22.782 1.00 9.22 ? 924 SER A C 1 ATOM 7457 O O . SER A 1 924 ? 45.665 66.978 -22.763 1.00 11.31 ? 924 SER A O 1 ATOM 7458 C CB . SER A 1 924 ? 44.833 65.167 -25.170 1.00 10.24 ? 924 SER A CB 1 ATOM 7459 O OG . SER A 1 924 ? 43.451 65.583 -25.100 1.00 11.87 ? 924 SER A OG 1 ATOM 7460 N N . LEU A 1 925 ? 43.978 65.665 -22.019 1.00 8.67 ? 925 LEU A N 1 ATOM 7461 C CA . LEU A 1 925 ? 43.514 66.602 -21.001 1.00 8.10 ? 925 LEU A CA 1 ATOM 7462 C C . LEU A 1 925 ? 44.256 66.415 -19.690 1.00 9.08 ? 925 LEU A C 1 ATOM 7463 O O . LEU A 1 925 ? 44.635 67.384 -19.044 1.00 10.50 ? 925 LEU A O 1 ATOM 7464 C CB . LEU A 1 925 ? 41.990 66.423 -20.719 1.00 7.87 ? 925 LEU A CB 1 ATOM 7465 C CG . LEU A 1 925 ? 41.108 66.687 -21.966 1.00 7.96 ? 925 LEU A CG 1 ATOM 7466 C CD1 . LEU A 1 925 ? 39.665 66.302 -21.594 1.00 10.74 ? 925 LEU A CD1 1 ATOM 7467 C CD2 . LEU A 1 925 ? 41.223 68.189 -22.394 1.00 11.19 ? 925 LEU A CD2 1 ATOM 7468 N N . LEU A 1 926 ? 44.424 65.171 -19.251 1.00 7.37 ? 926 LEU A N 1 ATOM 7469 C CA . LEU A 1 926 ? 45.001 64.909 -17.930 1.00 7.66 ? 926 LEU A CA 1 ATOM 7470 C C . LEU A 1 926 ? 46.504 64.885 -17.914 1.00 8.25 ? 926 LEU A C 1 ATOM 7471 O O . LEU A 1 926 ? 47.095 65.277 -16.870 1.00 9.30 ? 926 LEU A O 1 ATOM 7472 C CB . LEU A 1 926 ? 44.446 63.600 -17.365 1.00 10.24 ? 926 LEU A CB 1 ATOM 7473 C CG . LEU A 1 926 ? 42.909 63.664 -17.141 1.00 10.78 ? 926 LEU A CG 1 ATOM 7474 C CD1 . LEU A 1 926 ? 42.423 62.271 -16.564 1.00 13.76 ? 926 LEU A CD1 1 ATOM 7475 C CD2 . LEU A 1 926 ? 42.594 64.828 -16.140 1.00 14.68 ? 926 LEU A CD2 1 ATOM 7476 N N . ASP A 1 927 ? 47.124 64.385 -18.961 1.00 8.14 ? 927 ASP A N 1 ATOM 7477 C CA . ASP A 1 927 ? 48.592 64.305 -18.996 1.00 8.53 ? 927 ASP A CA 1 ATOM 7478 C C . ASP A 1 927 ? 49.153 64.835 -20.308 1.00 8.94 ? 927 ASP A C 1 ATOM 7479 O O . ASP A 1 927 ? 49.711 64.119 -21.106 1.00 8.18 ? 927 ASP A O 1 ATOM 7480 C CB . ASP A 1 927 ? 49.017 62.858 -18.754 1.00 9.15 ? 927 ASP A CB 1 ATOM 7481 C CG . ASP A 1 927 ? 48.749 62.420 -17.305 1.00 9.11 ? 927 ASP A CG 1 ATOM 7482 O OD1 . ASP A 1 927 ? 49.456 62.823 -16.322 1.00 9.80 ? 927 ASP A OD1 1 ATOM 7483 O OD2 . ASP A 1 927 ? 47.740 61.729 -17.149 1.00 10.92 ? 927 ASP A OD2 1 ATOM 7484 N N . PRO A 1 928 ? 48.974 66.149 -20.528 1.00 8.92 ? 928 PRO A N 1 ATOM 7485 C CA . PRO A 1 928 ? 49.477 66.781 -21.766 1.00 8.40 ? 928 PRO A CA 1 ATOM 7486 C C . PRO A 1 928 ? 51.020 66.795 -21.770 1.00 8.47 ? 928 PRO A C 1 ATOM 7487 O O . PRO A 1 928 ? 51.678 66.496 -20.761 1.00 8.74 ? 928 PRO A O 1 ATOM 7488 C CB . PRO A 1 928 ? 48.975 68.235 -21.657 1.00 10.54 ? 928 PRO A CB 1 ATOM 7489 C CG . PRO A 1 928 ? 48.958 68.502 -20.191 1.00 12.36 ? 928 PRO A CG 1 ATOM 7490 C CD . PRO A 1 928 ? 48.396 67.152 -19.592 1.00 10.03 ? 928 PRO A CD 1 ATOM 7491 N N . LEU A 1 929 ? 51.623 67.161 -22.897 1.00 8.69 ? 929 LEU A N 1 ATOM 7492 C CA . LEU A 1 929 ? 53.045 67.416 -22.884 1.00 7.80 ? 929 LEU A CA 1 ATOM 7493 C C . LEU A 1 929 ? 53.368 68.572 -21.945 1.00 8.10 ? 929 LEU A C 1 ATOM 7494 O O . LEU A 1 929 ? 52.598 69.528 -21.849 1.00 11.23 ? 929 LEU A O 1 ATOM 7495 C CB . LEU A 1 929 ? 53.543 67.825 -24.300 1.00 9.55 ? 929 LEU A CB 1 ATOM 7496 C CG . LEU A 1 929 ? 53.364 66.796 -25.418 1.00 9.21 ? 929 LEU A CG 1 ATOM 7497 C CD1 . LEU A 1 929 ? 53.969 67.388 -26.724 1.00 10.46 ? 929 LEU A CD1 1 ATOM 7498 C CD2 . LEU A 1 929 ? 54.069 65.449 -25.071 1.00 9.12 ? 929 LEU A CD2 1 ATOM 7499 N N . ASP A 1 930 ? 54.484 68.512 -21.246 1.00 8.02 ? 930 ASP A N 1 ATOM 7500 C CA . ASP A 1 930 ? 54.976 69.626 -20.435 1.00 7.90 ? 930 ASP A CA 1 ATOM 7501 C C . ASP A 1 930 ? 55.884 70.478 -21.320 1.00 9.14 ? 930 ASP A C 1 ATOM 7502 O O . ASP A 1 930 ? 56.672 69.906 -22.147 1.00 10.45 ? 930 ASP A O 1 ATOM 7503 C CB . ASP A 1 930 ? 55.741 69.082 -19.217 1.00 8.48 ? 930 ASP A CB 1 ATOM 7504 C CG . ASP A 1 930 ? 54.944 68.056 -18.506 1.00 11.18 ? 930 ASP A CG 1 ATOM 7505 O OD1 . ASP A 1 930 ? 53.877 68.495 -18.014 1.00 13.79 ? 930 ASP A OD1 1 ATOM 7506 O OD2 . ASP A 1 930 ? 55.307 66.849 -18.461 1.00 11.14 ? 930 ASP A OD2 1 ATOM 7507 N N . LYS A 1 931 ? 55.889 71.790 -21.099 1.00 9.43 ? 931 LYS A N 1 ATOM 7508 C CA . LYS A 1 931 ? 56.679 72.702 -21.935 1.00 8.93 ? 931 LYS A CA 1 ATOM 7509 C C . LYS A 1 931 ? 57.621 73.505 -21.080 1.00 9.63 ? 931 LYS A C 1 ATOM 7510 O O . LYS A 1 931 ? 57.210 74.111 -20.076 1.00 11.16 ? 931 LYS A O 1 ATOM 7511 C CB . LYS A 1 931 ? 55.717 73.666 -22.662 1.00 10.19 ? 931 LYS A CB 1 ATOM 7512 C CG . LYS A 1 931 ? 54.713 72.952 -23.617 1.00 12.71 ? 931 LYS A CG 1 ATOM 7513 C CD . LYS A 1 931 ? 53.843 74.003 -24.305 1.00 16.85 ? 931 LYS A CD 1 ATOM 7514 C CE . LYS A 1 931 ? 52.832 74.543 -23.323 1.00 22.09 ? 931 LYS A CE 1 ATOM 7515 N NZ . LYS A 1 931 ? 52.349 75.805 -23.803 1.00 18.68 ? 931 LYS A NZ 1 ATOM 7516 N N . PHE A 1 932 ? 58.898 73.566 -21.466 1.00 8.38 ? 932 PHE A N 1 ATOM 7517 C CA . PHE A 1 932 ? 59.936 74.267 -20.727 1.00 7.88 ? 932 PHE A CA 1 ATOM 7518 C C . PHE A 1 932 ? 60.609 75.285 -21.632 1.00 8.70 ? 932 PHE A C 1 ATOM 7519 O O . PHE A 1 932 ? 60.937 74.964 -22.764 1.00 10.28 ? 932 PHE A O 1 ATOM 7520 C CB . PHE A 1 932 ? 61.003 73.283 -20.256 1.00 9.30 ? 932 PHE A CB 1 ATOM 7521 C CG . PHE A 1 932 ? 60.465 72.182 -19.368 1.00 9.53 ? 932 PHE A CG 1 ATOM 7522 C CD1 . PHE A 1 932 ? 59.862 71.026 -19.889 1.00 9.89 ? 932 PHE A CD1 1 ATOM 7523 C CD2 . PHE A 1 932 ? 60.590 72.309 -17.997 1.00 12.14 ? 932 PHE A CD2 1 ATOM 7524 C CE1 . PHE A 1 932 ? 59.387 69.971 -19.032 1.00 9.72 ? 932 PHE A CE1 1 ATOM 7525 C CE2 . PHE A 1 932 ? 60.138 71.290 -17.143 1.00 12.65 ? 932 PHE A CE2 1 ATOM 7526 C CZ . PHE A 1 932 ? 59.543 70.138 -17.670 1.00 12.09 ? 932 PHE A CZ 1 ATOM 7527 N N . ILE A 1 933 ? 60.824 76.485 -21.114 1.00 9.48 ? 933 ILE A N 1 ATOM 7528 C CA . ILE A 1 933 ? 61.479 77.551 -21.883 1.00 9.54 ? 933 ILE A CA 1 ATOM 7529 C C . ILE A 1 933 ? 62.843 77.803 -21.223 1.00 9.42 ? 933 ILE A C 1 ATOM 7530 O O . ILE A 1 933 ? 62.903 78.076 -20.003 1.00 10.01 ? 933 ILE A O 1 ATOM 7531 C CB . ILE A 1 933 ? 60.679 78.874 -21.817 1.00 9.27 ? 933 ILE A CB 1 ATOM 7532 C CG1 . ILE A 1 933 ? 59.270 78.686 -22.398 1.00 10.09 ? 933 ILE A CG1 1 ATOM 7533 C CG2 . ILE A 1 933 ? 61.464 79.981 -22.583 1.00 10.32 ? 933 ILE A CG2 1 ATOM 7534 C CD1 . ILE A 1 933 ? 58.387 79.874 -22.105 1.00 11.76 ? 933 ILE A CD1 1 ATOM 7535 N N . PHE A 1 934 ? 63.960 77.667 -21.983 1.00 9.12 ? 934 PHE A N 1 ATOM 7536 C CA . PHE A 1 934 ? 65.284 77.871 -21.370 1.00 10.00 ? 934 PHE A CA 1 ATOM 7537 C C . PHE A 1 934 ? 65.406 79.341 -20.902 1.00 11.14 ? 934 PHE A C 1 ATOM 7538 O O . PHE A 1 934 ? 65.103 80.257 -21.656 1.00 11.51 ? 934 PHE A O 1 ATOM 7539 C CB . PHE A 1 934 ? 66.390 77.499 -22.375 1.00 11.78 ? 934 PHE A CB 1 ATOM 7540 C CG . PHE A 1 934 ? 67.755 77.531 -21.762 1.00 11.20 ? 934 PHE A CG 1 ATOM 7541 C CD1 . PHE A 1 934 ? 68.155 76.535 -20.882 1.00 12.40 ? 934 PHE A CD1 1 ATOM 7542 C CD2 . PHE A 1 934 ? 68.619 78.599 -22.022 1.00 14.29 ? 934 PHE A CD2 1 ATOM 7543 C CE1 . PHE A 1 934 ? 69.403 76.581 -20.247 1.00 17.14 ? 934 PHE A CE1 1 ATOM 7544 C CE2 . PHE A 1 934 ? 69.842 78.679 -21.420 1.00 16.49 ? 934 PHE A CE2 1 ATOM 7545 C CZ . PHE A 1 934 ? 70.262 77.682 -20.522 1.00 19.19 ? 934 PHE A CZ 1 ATOM 7546 N N . ALA A 1 935 ? 65.839 79.553 -19.666 1.00 10.55 ? 935 ALA A N 1 ATOM 7547 C CA . ALA A 1 935 ? 65.804 80.895 -19.111 1.00 11.70 ? 935 ALA A CA 1 ATOM 7548 C C . ALA A 1 935 ? 66.938 81.834 -19.577 1.00 17.83 ? 935 ALA A C 1 ATOM 7549 O O . ALA A 1 935 ? 66.680 83.040 -19.892 1.00 21.92 ? 935 ALA A O 1 ATOM 7550 C CB . ALA A 1 935 ? 65.799 80.803 -17.610 1.00 15.70 ? 935 ALA A CB 1 ATOM 7551 N N . GLU A 1 936 ? 68.141 81.307 -19.715 1.00 14.14 ? 936 GLU A N 1 ATOM 7552 C CA . GLU A 1 936 ? 69.313 82.133 -20.053 1.00 16.14 ? 936 GLU A CA 1 ATOM 7553 C C . GLU A 1 936 ? 69.420 82.323 -21.546 1.00 15.50 ? 936 GLU A C 1 ATOM 7554 O O . GLU A 1 936 ? 68.669 81.752 -22.334 1.00 15.22 ? 936 GLU A O 1 ATOM 7555 C CB . GLU A 1 936 ? 70.599 81.445 -19.528 1.00 20.97 ? 936 GLU A CB 1 ATOM 7556 C CG . GLU A 1 936 ? 70.749 81.189 -17.986 1.00 25.85 ? 936 GLU A CG 1 ATOM 7557 C CD . GLU A 1 936 ? 71.856 80.100 -17.677 1.00 31.21 ? 936 GLU A CD 1 ATOM 7558 O OE1 . GLU A 1 936 ? 71.634 78.870 -17.899 1.00 27.65 ? 936 GLU A OE1 1 ATOM 7559 O OE2 . GLU A 1 936 ? 72.980 80.458 -17.240 1.00 33.51 ? 936 GLU A OE2 1 ATOM 7560 N N . ASN A 1 937 ? 70.399 83.119 -21.982 1.00 15.89 ? 937 ASN A N 1 ATOM 7561 C CA . ASN A 1 937 ? 70.529 83.351 -23.408 1.00 15.57 ? 937 ASN A CA 1 ATOM 7562 C C . ASN A 1 937 ? 71.075 82.186 -24.197 1.00 13.10 ? 937 ASN A C 1 ATOM 7563 O O . ASN A 1 937 ? 70.661 81.977 -25.342 1.00 14.83 ? 937 ASN A O 1 ATOM 7564 C CB . ASN A 1 937 ? 71.430 84.573 -23.667 1.00 17.22 ? 937 ASN A CB 1 ATOM 7565 C CG . ASN A 1 937 ? 70.751 85.877 -23.250 1.00 20.46 ? 937 ASN A CG 1 ATOM 7566 O OD1 . ASN A 1 937 ? 69.505 85.945 -23.150 1.00 18.88 ? 937 ASN A OD1 1 ATOM 7567 N ND2 . ASN A 1 937 ? 71.556 86.908 -23.007 1.00 24.31 ? 937 ASN A ND2 1 ATOM 7568 N N . GLU A 1 938 ? 72.009 81.438 -23.602 1.00 14.79 ? 938 GLU A N 1 ATOM 7569 C CA . GLU A 1 938 ? 72.630 80.342 -24.321 1.00 17.17 ? 938 GLU A CA 1 ATOM 7570 C C . GLU A 1 938 ? 72.725 79.088 -23.459 1.00 13.88 ? 938 GLU A C 1 ATOM 7571 O O . GLU A 1 938 ? 73.124 79.166 -22.342 1.00 16.75 ? 938 GLU A O 1 ATOM 7572 C CB . GLU A 1 938 ? 74.057 80.732 -24.786 1.00 20.14 ? 938 GLU A CB 1 ATOM 7573 C CG . GLU A 1 938 ? 74.706 79.548 -25.515 1.00 26.47 ? 938 GLU A CG 1 ATOM 7574 C CD . GLU A 1 938 ? 76.026 79.842 -26.207 1.00 34.34 ? 938 GLU A CD 1 ATOM 7575 O OE1 . GLU A 1 938 ? 76.808 80.679 -25.708 1.00 34.91 ? 938 GLU A OE1 1 ATOM 7576 O OE2 . GLU A 1 938 ? 76.277 79.188 -27.251 1.00 36.33 ? 938 GLU A OE2 1 ATOM 7577 N N . TRP A 1 939 ? 72.340 77.953 -24.044 1.00 16.02 ? 939 TRP A N 1 ATOM 7578 C CA . TRP A 1 939 ? 72.406 76.653 -23.324 1.00 13.83 ? 939 TRP A CA 1 ATOM 7579 C C . TRP A 1 939 ? 73.603 75.855 -23.875 1.00 15.96 ? 939 TRP A C 1 ATOM 7580 O O . TRP A 1 939 ? 73.518 75.227 -24.923 1.00 18.57 ? 939 TRP A O 1 ATOM 7581 C CB . TRP A 1 939 ? 71.076 75.916 -23.572 1.00 14.02 ? 939 TRP A CB 1 ATOM 7582 C CG . TRP A 1 939 ? 70.956 74.585 -22.905 1.00 12.23 ? 939 TRP A CG 1 ATOM 7583 C CD1 . TRP A 1 939 ? 71.841 73.963 -22.075 1.00 13.01 ? 939 TRP A CD1 1 ATOM 7584 C CD2 . TRP A 1 939 ? 69.866 73.702 -23.108 1.00 12.17 ? 939 TRP A CD2 1 ATOM 7585 N NE1 . TRP A 1 939 ? 71.354 72.693 -21.750 1.00 12.49 ? 939 TRP A NE1 1 ATOM 7586 C CE2 . TRP A 1 939 ? 70.138 72.518 -22.365 1.00 11.08 ? 939 TRP A CE2 1 ATOM 7587 C CE3 . TRP A 1 939 ? 68.687 73.789 -23.845 1.00 11.91 ? 939 TRP A CE3 1 ATOM 7588 C CZ2 . TRP A 1 939 ? 69.255 71.427 -22.351 1.00 11.19 ? 939 TRP A CZ2 1 ATOM 7589 C CZ3 . TRP A 1 939 ? 67.794 72.721 -23.843 1.00 10.88 ? 939 TRP A CZ3 1 ATOM 7590 C CH2 . TRP A 1 939 ? 68.090 71.545 -23.096 1.00 11.92 ? 939 TRP A CH2 1 ATOM 7591 N N . ILE A 1 940 ? 74.717 75.917 -23.152 1.00 19.67 ? 940 ILE A N 1 ATOM 7592 C CA . ILE A 1 940 ? 75.912 75.194 -23.609 1.00 21.65 ? 940 ILE A CA 1 ATOM 7593 C C . ILE A 1 940 ? 75.767 73.669 -23.369 1.00 16.25 ? 940 ILE A C 1 ATOM 7594 O O . ILE A 1 940 ? 75.354 73.250 -22.283 1.00 17.19 ? 940 ILE A O 1 ATOM 7595 C CB . ILE A 1 940 ? 77.165 75.734 -22.867 1.00 24.15 ? 940 ILE A CB 1 ATOM 7596 C CG1 . ILE A 1 940 ? 77.291 77.243 -23.127 1.00 26.44 ? 940 ILE A CG1 1 ATOM 7597 C CG2 . ILE A 1 940 ? 78.446 74.996 -23.345 1.00 24.33 ? 940 ILE A CG2 1 ATOM 7598 C CD1 . ILE A 1 940 ? 78.608 77.819 -22.681 1.00 31.41 ? 940 ILE A CD1 1 ATOM 7599 N N . GLY A 1 941 ? 76.050 72.874 -24.385 1.00 17.44 ? 941 GLY A N 1 ATOM 7600 C CA . GLY A 1 941 ? 75.983 71.419 -24.189 1.00 16.18 ? 941 GLY A CA 1 ATOM 7601 C C . GLY A 1 941 ? 74.586 70.857 -24.396 1.00 17.17 ? 941 GLY A C 1 ATOM 7602 O O . GLY A 1 941 ? 74.364 69.694 -24.074 1.00 15.73 ? 941 GLY A O 1 ATOM 7603 N N . ALA A 1 942 ? 73.663 71.648 -24.965 1.00 14.93 ? 942 ALA A N 1 ATOM 7604 C CA . ALA A 1 942 ? 72.278 71.182 -25.163 1.00 13.71 ? 942 ALA A CA 1 ATOM 7605 C C . ALA A 1 942 ? 72.206 69.984 -26.083 1.00 16.94 ? 942 ALA A C 1 ATOM 7606 O O . ALA A 1 942 ? 72.916 69.922 -27.080 1.00 19.15 ? 942 ALA A O 1 ATOM 7607 C CB . ALA A 1 942 ? 71.447 72.307 -25.718 1.00 16.65 ? 942 ALA A CB 1 ATOM 7608 N N . GLN A 1 943 ? 71.322 69.036 -25.778 1.00 14.03 ? 943 GLN A N 1 ATOM 7609 C CA . GLN A 1 943 ? 71.082 67.866 -26.564 1.00 15.65 ? 943 GLN A CA 1 ATOM 7610 C C . GLN A 1 943 ? 69.649 67.881 -27.099 1.00 11.73 ? 943 GLN A C 1 ATOM 7611 O O . GLN A 1 943 ? 68.734 68.516 -26.475 1.00 15.19 ? 943 GLN A O 1 ATOM 7612 C CB . GLN A 1 943 ? 71.305 66.610 -25.716 1.00 15.95 ? 943 GLN A CB 1 ATOM 7613 C CG . GLN A 1 943 ? 72.719 66.534 -25.196 1.00 21.54 ? 943 GLN A CG 1 ATOM 7614 C CD . GLN A 1 943 ? 72.926 65.313 -24.309 1.00 24.10 ? 943 GLN A CD 1 ATOM 7615 O OE1 . GLN A 1 943 ? 71.986 64.871 -23.619 1.00 28.70 ? 943 GLN A OE1 1 ATOM 7616 N NE2 . GLN A 1 943 ? 74.152 64.776 -24.302 1.00 25.70 ? 943 GLN A NE2 1 ATOM 7617 N N . GLY A 1 944 ? 69.400 67.188 -28.178 1.00 12.79 ? 944 GLY A N 1 ATOM 7618 C CA . GLY A 1 944 ? 68.129 67.261 -28.822 1.00 14.09 ? 944 GLY A CA 1 ATOM 7619 C C . GLY A 1 944 ? 67.020 66.366 -28.360 1.00 14.19 ? 944 GLY A C 1 ATOM 7620 O O . GLY A 1 944 ? 65.871 66.646 -28.630 1.00 14.61 ? 944 GLY A O 1 ATOM 7621 N N . GLN A 1 945 ? 67.351 65.295 -27.665 1.00 12.65 ? 945 GLN A N 1 ATOM 7622 C CA . GLN A 1 945 ? 66.314 64.335 -27.301 1.00 13.36 ? 945 GLN A CA 1 ATOM 7623 C C . GLN A 1 945 ? 66.780 63.470 -26.161 1.00 12.85 ? 945 GLN A C 1 ATOM 7624 O O . GLN A 1 945 ? 67.985 63.259 -25.980 1.00 14.19 ? 945 GLN A O 1 ATOM 7625 C CB . GLN A 1 945 ? 66.086 63.428 -28.489 1.00 14.37 ? 945 GLN A CB 1 ATOM 7626 C CG . GLN A 1 945 ? 64.877 62.512 -28.463 1.00 18.33 ? 945 GLN A CG 1 ATOM 7627 C CD . GLN A 1 945 ? 64.851 61.575 -29.686 1.00 19.99 ? 945 GLN A CD 1 ATOM 7628 O OE1 . GLN A 1 945 ? 64.013 61.720 -30.562 1.00 25.24 ? 945 GLN A OE1 1 ATOM 7629 N NE2 . GLN A 1 945 ? 65.763 60.633 -29.725 1.00 23.52 ? 945 GLN A NE2 1 ATOM 7630 N N . PHE A 1 946 ? 65.804 62.987 -25.385 1.00 10.26 ? 946 PHE A N 1 ATOM 7631 C CA . PHE A 1 946 ? 66.056 61.990 -24.322 1.00 9.82 ? 946 PHE A CA 1 ATOM 7632 C C . PHE A 1 946 ? 64.963 60.961 -24.439 1.00 10.52 ? 946 PHE A C 1 ATOM 7633 O O . PHE A 1 946 ? 63.789 61.280 -24.658 1.00 10.84 ? 946 PHE A O 1 ATOM 7634 C CB . PHE A 1 946 ? 66.064 62.601 -22.914 1.00 10.78 ? 946 PHE A CB 1 ATOM 7635 C CG . PHE A 1 946 ? 65.950 61.582 -21.814 1.00 11.24 ? 946 PHE A CG 1 ATOM 7636 C CD1 . PHE A 1 946 ? 66.974 60.739 -21.502 1.00 12.37 ? 946 PHE A CD1 1 ATOM 7637 C CD2 . PHE A 1 946 ? 64.736 61.460 -21.126 1.00 11.13 ? 946 PHE A CD2 1 ATOM 7638 C CE1 . PHE A 1 946 ? 66.818 59.723 -20.489 1.00 12.54 ? 946 PHE A CE1 1 ATOM 7639 C CE2 . PHE A 1 946 ? 64.561 60.448 -20.128 1.00 11.76 ? 946 PHE A CE2 1 ATOM 7640 C CZ . PHE A 1 946 ? 65.591 59.593 -19.826 1.00 11.89 ? 946 PHE A CZ 1 ATOM 7641 N N . GLY A 1 947 ? 65.310 59.666 -24.333 1.00 10.99 ? 947 GLY A N 1 ATOM 7642 C CA . GLY A 1 947 ? 64.301 58.626 -24.371 1.00 12.24 ? 947 GLY A CA 1 ATOM 7643 C C . GLY A 1 947 ? 63.982 58.020 -25.710 1.00 11.86 ? 947 GLY A C 1 ATOM 7644 O O . GLY A 1 947 ? 63.067 57.248 -25.818 1.00 12.87 ? 947 GLY A O 1 ATOM 7645 N N . GLY A 1 948 ? 64.772 58.351 -26.766 1.00 13.67 ? 948 GLY A N 1 ATOM 7646 C CA . GLY A 1 948 ? 64.505 57.794 -28.080 1.00 13.74 ? 948 GLY A CA 1 ATOM 7647 C C . GLY A 1 948 ? 64.544 56.273 -28.109 1.00 14.31 ? 948 GLY A C 1 ATOM 7648 O O . GLY A 1 948 ? 63.911 55.686 -29.000 1.00 19.24 ? 948 GLY A O 1 ATOM 7649 N N . ASP A 1 949 ? 65.257 55.651 -27.171 1.00 15.80 ? 949 ASP A N 1 ATOM 7650 C CA . ASP A 1 949 ? 65.318 54.193 -27.094 1.00 18.47 ? 949 ASP A CA 1 ATOM 7651 C C . ASP A 1 949 ? 64.346 53.577 -26.087 1.00 18.94 ? 949 ASP A C 1 ATOM 7652 O O . ASP A 1 949 ? 64.392 52.346 -25.803 1.00 19.45 ? 949 ASP A O 1 ATOM 7653 C CB . ASP A 1 949 ? 66.758 53.733 -26.736 1.00 20.04 ? 949 ASP A CB 1 ATOM 7654 C CG . ASP A 1 949 ? 67.259 54.295 -25.419 1.00 27.95 ? 949 ASP A CG 1 ATOM 7655 O OD1 . ASP A 1 949 ? 66.637 55.208 -24.775 1.00 28.34 ? 949 ASP A OD1 1 ATOM 7656 O OD2 . ASP A 1 949 ? 68.339 53.816 -24.981 1.00 32.84 ? 949 ASP A OD2 1 ATOM 7657 N N . HIS A 1 950 ? 63.465 54.406 -25.503 1.00 15.44 ? 950 HIS A N 1 ATOM 7658 C CA . HIS A 1 950 ? 62.481 53.844 -24.561 1.00 12.69 ? 950 HIS A CA 1 ATOM 7659 C C . HIS A 1 950 ? 61.388 53.090 -25.370 1.00 12.55 ? 950 HIS A C 1 ATOM 7660 O O . HIS A 1 950 ? 60.966 53.518 -26.428 1.00 14.24 ? 950 HIS A O 1 ATOM 7661 C CB . HIS A 1 950 ? 61.765 54.930 -23.800 1.00 11.82 ? 950 HIS A CB 1 ATOM 7662 C CG . HIS A 1 950 ? 62.604 55.731 -22.857 1.00 11.98 ? 950 HIS A CG 1 ATOM 7663 N ND1 . HIS A 1 950 ? 63.875 55.432 -22.371 1.00 14.18 ? 950 HIS A ND1 1 ATOM 7664 C CD2 . HIS A 1 950 ? 62.231 56.862 -22.231 1.00 8.14 ? 950 HIS A CD2 1 ATOM 7665 C CE1 . HIS A 1 950 ? 64.229 56.366 -21.496 1.00 10.38 ? 950 HIS A CE1 1 ATOM 7666 N NE2 . HIS A 1 950 ? 63.233 57.244 -21.408 1.00 14.25 ? 950 HIS A NE2 1 ATOM 7667 N N . PRO A 1 951 ? 60.933 51.939 -24.904 1.00 13.49 ? 951 PRO A N 1 ATOM 7668 C CA . PRO A 1 951 ? 59.910 51.194 -25.623 1.00 13.37 ? 951 PRO A CA 1 ATOM 7669 C C . PRO A 1 951 ? 58.619 51.990 -25.786 1.00 12.76 ? 951 PRO A C 1 ATOM 7670 O O . PRO A 1 951 ? 58.178 52.684 -24.803 1.00 13.08 ? 951 PRO A O 1 ATOM 7671 C CB . PRO A 1 951 ? 59.647 49.961 -24.736 1.00 16.51 ? 951 PRO A CB 1 ATOM 7672 C CG . PRO A 1 951 ? 60.899 49.760 -24.048 1.00 19.65 ? 951 PRO A CG 1 ATOM 7673 C CD . PRO A 1 951 ? 61.439 51.201 -23.738 1.00 16.57 ? 951 PRO A CD 1 ATOM 7674 N N . SER A 1 952 ? 57.969 51.877 -26.921 1.00 12.38 ? 952 SER A N 1 ATOM 7675 C CA . SER A 1 952 ? 56.705 52.586 -27.151 1.00 11.99 ? 952 SER A CA 1 ATOM 7676 C C . SER A 1 952 ? 55.637 51.533 -26.948 1.00 12.71 ? 952 SER A C 1 ATOM 7677 O O . SER A 1 952 ? 55.377 50.691 -27.838 1.00 13.79 ? 952 SER A O 1 ATOM 7678 C CB . SER A 1 952 ? 56.675 53.172 -28.581 1.00 11.90 ? 952 SER A CB 1 ATOM 7679 O OG . SER A 1 952 ? 55.635 54.124 -28.694 1.00 13.06 ? 952 SER A OG 1 ATOM 7680 N N . ALA A 1 953 ? 54.994 51.560 -25.778 1.00 12.28 ? 953 ALA A N 1 ATOM 7681 C CA . ALA A 1 953 ? 54.025 50.528 -25.363 1.00 11.06 ? 953 ALA A CA 1 ATOM 7682 C C . ALA A 1 953 ? 52.665 50.614 -25.991 1.00 11.09 ? 953 ALA A C 1 ATOM 7683 O O . ALA A 1 953 ? 52.253 51.687 -26.457 1.00 11.15 ? 953 ALA A O 1 ATOM 7684 C CB . ALA A 1 953 ? 53.875 50.584 -23.813 1.00 13.56 ? 953 ALA A CB 1 ATOM 7685 N N . ARG A 1 954 ? 51.951 49.502 -26.029 1.00 10.87 ? 954 ARG A N 1 ATOM 7686 C CA . ARG A 1 954 ? 50.609 49.497 -26.559 1.00 11.80 ? 954 ARG A CA 1 ATOM 7687 C C . ARG A 1 954 ? 49.789 50.656 -25.923 1.00 10.08 ? 954 ARG A C 1 ATOM 7688 O O . ARG A 1 954 ? 49.884 50.953 -24.710 1.00 10.52 ? 954 ARG A O 1 ATOM 7689 C CB . ARG A 1 954 ? 49.946 48.147 -26.320 1.00 13.56 ? 954 ARG A CB 1 ATOM 7690 C CG . ARG A 1 954 ? 48.709 47.967 -27.258 1.00 20.35 ? 954 ARG A CG 1 ATOM 7691 C CD . ARG A 1 954 ? 48.231 46.517 -27.443 1.00 21.87 ? 954 ARG A CD 1 ATOM 7692 N NE . ARG A 1 954 ? 47.212 46.243 -26.447 1.00 23.70 ? 954 ARG A NE 1 ATOM 7693 C CZ . ARG A 1 954 ? 46.567 45.097 -26.315 1.00 30.45 ? 954 ARG A CZ 1 ATOM 7694 N NH1 . ARG A 1 954 ? 46.833 44.074 -27.142 1.00 32.77 ? 954 ARG A NH1 1 ATOM 7695 N NH2 . ARG A 1 954 ? 45.659 44.972 -25.363 1.00 26.98 ? 954 ARG A NH2 1 ATOM 7696 N N . GLU A 1 955 ? 48.867 51.206 -26.699 1.00 10.63 ? 955 GLU A N 1 ATOM 7697 C CA . GLU A 1 955 ? 48.140 52.427 -26.304 1.00 11.64 ? 955 GLU A CA 1 ATOM 7698 C C . GLU A 1 955 ? 47.308 52.302 -25.033 1.00 10.38 ? 955 GLU A C 1 ATOM 7699 O O . GLU A 1 955 ? 46.995 53.311 -24.406 1.00 11.50 ? 955 GLU A O 1 ATOM 7700 C CB . GLU A 1 955 ? 47.237 52.881 -27.472 1.00 13.60 ? 955 GLU A CB 1 ATOM 7701 C CG . GLU A 1 955 ? 46.163 51.883 -27.827 1.00 14.19 ? 955 GLU A CG 1 ATOM 7702 C CD . GLU A 1 955 ? 45.230 52.381 -28.869 1.00 20.05 ? 955 GLU A CD 1 ATOM 7703 O OE1 . GLU A 1 955 ? 45.075 53.606 -29.029 1.00 24.99 ? 955 GLU A OE1 1 ATOM 7704 O OE2 . GLU A 1 955 ? 44.594 51.543 -29.555 1.00 20.88 ? 955 GLU A OE2 1 ATOM 7705 N N . ASP A 1 956 ? 46.878 51.071 -24.693 1.00 9.25 ? 956 ASP A N 1 ATOM 7706 C CA . ASP A 1 956 ? 46.088 50.908 -23.477 1.00 9.98 ? 956 ASP A CA 1 ATOM 7707 C C . ASP A 1 956 ? 46.898 50.803 -22.216 1.00 8.44 ? 956 ASP A C 1 ATOM 7708 O O . ASP A 1 956 ? 46.307 50.738 -21.127 1.00 11.56 ? 956 ASP A O 1 ATOM 7709 C CB . ASP A 1 956 ? 45.086 49.714 -23.630 1.00 11.56 ? 956 ASP A CB 1 ATOM 7710 C CG . ASP A 1 956 ? 45.737 48.409 -23.989 1.00 12.91 ? 956 ASP A CG 1 ATOM 7711 O OD1 . ASP A 1 956 ? 46.936 48.362 -24.190 1.00 15.49 ? 956 ASP A OD1 1 ATOM 7712 O OD2 . ASP A 1 956 ? 44.967 47.400 -24.038 1.00 14.86 ? 956 ASP A OD2 1 ATOM 7713 N N . LEU A 1 957 ? 48.208 50.796 -22.333 1.00 8.96 ? 957 LEU A N 1 ATOM 7714 C CA . LEU A 1 957 ? 49.077 50.661 -21.144 1.00 9.10 ? 957 LEU A CA 1 ATOM 7715 C C . LEU A 1 957 ? 49.640 52.014 -20.708 1.00 9.81 ? 957 LEU A C 1 ATOM 7716 O O . LEU A 1 957 ? 50.066 52.827 -21.564 1.00 11.65 ? 957 LEU A O 1 ATOM 7717 C CB . LEU A 1 957 ? 50.267 49.728 -21.499 1.00 11.38 ? 957 LEU A CB 1 ATOM 7718 C CG . LEU A 1 957 ? 51.132 49.198 -20.340 1.00 14.52 ? 957 LEU A CG 1 ATOM 7719 C CD1 . LEU A 1 957 ? 50.250 48.319 -19.421 1.00 18.09 ? 957 LEU A CD1 1 ATOM 7720 C CD2 . LEU A 1 957 ? 52.255 48.307 -20.883 1.00 16.79 ? 957 LEU A CD2 1 ATOM 7721 N N . ASP A 1 958 ? 49.682 52.243 -19.407 1.00 8.49 ? 958 ASP A N 1 ATOM 7722 C CA . ASP A 1 958 ? 50.301 53.457 -18.891 1.00 7.94 ? 958 ASP A CA 1 ATOM 7723 C C . ASP A 1 958 ? 51.213 53.150 -17.733 1.00 8.02 ? 958 ASP A C 1 ATOM 7724 O O . ASP A 1 958 ? 50.980 52.184 -16.962 1.00 9.58 ? 958 ASP A O 1 ATOM 7725 C CB . ASP A 1 958 ? 49.210 54.453 -18.441 1.00 9.88 ? 958 ASP A CB 1 ATOM 7726 C CG . ASP A 1 958 ? 49.749 55.870 -18.226 1.00 8.55 ? 958 ASP A CG 1 ATOM 7727 O OD1 . ASP A 1 958 ? 50.866 56.195 -18.689 1.00 9.86 ? 958 ASP A OD1 1 ATOM 7728 O OD2 . ASP A 1 958 ? 49.043 56.667 -17.547 1.00 10.33 ? 958 ASP A OD2 1 ATOM 7729 N N . VAL A 1 959 ? 52.284 53.933 -17.620 1.00 7.91 ? 959 VAL A N 1 ATOM 7730 C CA . VAL A 1 959 ? 53.149 53.910 -16.433 1.00 7.85 ? 959 VAL A CA 1 ATOM 7731 C C . VAL A 1 959 ? 52.592 55.042 -15.585 1.00 8.09 ? 959 VAL A C 1 ATOM 7732 O O . VAL A 1 959 ? 53.008 56.205 -15.707 1.00 8.80 ? 959 VAL A O 1 ATOM 7733 C CB . VAL A 1 959 ? 54.605 54.166 -16.804 1.00 8.85 ? 959 VAL A CB 1 ATOM 7734 C CG1 . VAL A 1 959 ? 55.480 54.310 -15.503 1.00 9.42 ? 959 VAL A CG1 1 ATOM 7735 C CG2 . VAL A 1 959 ? 55.139 52.984 -17.650 1.00 9.94 ? 959 VAL A CG2 1 ATOM 7736 N N . SER A 1 960 ? 51.630 54.703 -14.738 1.00 8.16 ? 960 SER A N 1 ATOM 7737 C CA . SER A 1 960 ? 50.928 55.682 -13.907 1.00 8.40 ? 960 SER A CA 1 ATOM 7738 C C . SER A 1 960 ? 51.850 56.393 -12.948 1.00 8.97 ? 960 SER A C 1 ATOM 7739 O O . SER A 1 960 ? 51.677 57.599 -12.664 1.00 10.02 ? 960 SER A O 1 ATOM 7740 C CB . SER A 1 960 ? 49.806 54.988 -13.110 1.00 9.41 ? 960 SER A CB 1 ATOM 7741 O OG . SER A 1 960 ? 48.999 54.184 -13.983 1.00 11.76 ? 960 SER A OG 1 ATOM 7742 N N . VAL A 1 961 ? 52.818 55.646 -12.405 1.00 8.33 ? 961 VAL A N 1 ATOM 7743 C CA . VAL A 1 961 ? 53.815 56.150 -11.465 1.00 9.07 ? 961 VAL A CA 1 ATOM 7744 C C . VAL A 1 961 ? 55.174 55.590 -11.783 1.00 8.44 ? 961 VAL A C 1 ATOM 7745 O O . VAL A 1 961 ? 55.333 54.383 -12.030 1.00 8.01 ? 961 VAL A O 1 ATOM 7746 C CB . VAL A 1 961 ? 53.505 55.685 -10.010 1.00 9.00 ? 961 VAL A CB 1 ATOM 7747 C CG1 . VAL A 1 961 ? 54.619 56.163 -9.025 1.00 10.66 ? 961 VAL A CG1 1 ATOM 7748 C CG2 . VAL A 1 961 ? 52.143 56.250 -9.534 1.00 10.46 ? 961 VAL A CG2 1 ATOM 7749 N N . MET A 1 962 ? 56.172 56.485 -11.770 1.00 8.09 ? 962 MET A N 1 ATOM 7750 C CA . MET A 1 962 ? 57.579 56.053 -11.778 1.00 7.77 ? 962 MET A CA 1 ATOM 7751 C C . MET A 1 962 ? 58.178 56.882 -10.638 1.00 7.89 ? 962 MET A C 1 ATOM 7752 O O . MET A 1 962 ? 58.127 58.130 -10.618 1.00 9.33 ? 962 MET A O 1 ATOM 7753 C CB . MET A 1 962 ? 58.267 56.376 -13.093 1.00 8.86 ? 962 MET A CB 1 ATOM 7754 C CG . MET A 1 962 ? 59.795 56.080 -13.015 1.00 8.90 ? 962 MET A CG 1 ATOM 7755 S SD . MET A 1 962 ? 60.513 56.352 -14.642 1.00 10.64 ? 962 MET A SD 1 ATOM 7756 C CE . MET A 1 962 ? 62.272 55.896 -14.366 1.00 11.10 ? 962 MET A CE 1 ATOM 7757 N N . ARG A 1 963 ? 58.733 56.197 -9.621 1.00 8.02 ? 963 ARG A N 1 ATOM 7758 C CA . ARG A 1 963 ? 59.272 56.868 -8.453 1.00 7.71 ? 963 ARG A CA 1 ATOM 7759 C C . ARG A 1 963 ? 60.533 56.186 -7.945 1.00 8.30 ? 963 ARG A C 1 ATOM 7760 O O . ARG A 1 963 ? 60.472 54.996 -7.557 1.00 8.54 ? 963 ARG A O 1 ATOM 7761 C CB . ARG A 1 963 ? 58.201 56.825 -7.318 1.00 8.58 ? 963 ARG A CB 1 ATOM 7762 C CG . ARG A 1 963 ? 58.636 57.479 -5.985 1.00 8.94 ? 963 ARG A CG 1 ATOM 7763 C CD . ARG A 1 963 ? 57.581 57.284 -4.851 1.00 11.19 ? 963 ARG A CD 1 ATOM 7764 N NE . ARG A 1 963 ? 56.348 57.998 -5.227 1.00 10.36 ? 963 ARG A NE 1 ATOM 7765 C CZ . ARG A 1 963 ? 55.120 57.475 -5.171 1.00 9.34 ? 963 ARG A CZ 1 ATOM 7766 N NH1 . ARG A 1 963 ? 54.884 56.262 -4.655 1.00 9.40 ? 963 ARG A NH1 1 ATOM 7767 N NH2 . ARG A 1 963 ? 54.136 58.144 -5.818 1.00 9.86 ? 963 ARG A NH2 1 ATOM 7768 N N . ARG A 1 964 ? 61.635 56.937 -7.820 1.00 8.97 ? 964 ARG A N 1 ATOM 7769 C CA . ARG A 1 964 ? 62.833 56.314 -7.184 1.00 9.24 ? 964 ARG A CA 1 ATOM 7770 C C . ARG A 1 964 ? 62.523 56.265 -5.678 1.00 8.54 ? 964 ARG A C 1 ATOM 7771 O O . ARG A 1 964 ? 62.090 57.245 -5.087 1.00 9.56 ? 964 ARG A O 1 ATOM 7772 C CB . ARG A 1 964 ? 64.037 57.178 -7.502 1.00 8.63 ? 964 ARG A CB 1 ATOM 7773 C CG . ARG A 1 964 ? 65.312 56.511 -6.875 1.00 10.25 ? 964 ARG A CG 1 ATOM 7774 C CD . ARG A 1 964 ? 66.584 57.181 -7.383 1.00 10.92 ? 964 ARG A CD 1 ATOM 7775 N NE . ARG A 1 964 ? 66.801 57.020 -8.821 1.00 11.30 ? 964 ARG A NE 1 ATOM 7776 C CZ . ARG A 1 964 ? 67.666 56.222 -9.393 1.00 10.90 ? 964 ARG A CZ 1 ATOM 7777 N NH1 . ARG A 1 964 ? 68.440 55.436 -8.643 1.00 15.18 ? 964 ARG A NH1 1 ATOM 7778 N NH2 . ARG A 1 964 ? 67.808 56.212 -10.703 1.00 14.00 ? 964 ARG A NH2 1 ATOM 7779 N N . LEU A 1 965 ? 62.769 55.091 -5.098 1.00 9.38 ? 965 LEU A N 1 ATOM 7780 C CA . LEU A 1 965 ? 62.404 54.842 -3.701 1.00 8.85 ? 965 LEU A CA 1 ATOM 7781 C C . LEU A 1 965 ? 63.564 54.985 -2.722 1.00 10.24 ? 965 LEU A C 1 ATOM 7782 O O . LEU A 1 965 ? 63.321 54.906 -1.506 1.00 11.54 ? 965 LEU A O 1 ATOM 7783 C CB . LEU A 1 965 ? 61.866 53.440 -3.587 1.00 9.93 ? 965 LEU A CB 1 ATOM 7784 C CG . LEU A 1 965 ? 60.641 53.175 -4.484 1.00 9.56 ? 965 LEU A CG 1 ATOM 7785 C CD1 . LEU A 1 965 ? 60.203 51.700 -4.379 1.00 11.12 ? 965 LEU A CD1 1 ATOM 7786 C CD2 . LEU A 1 965 ? 59.457 54.071 -4.061 1.00 13.79 ? 965 LEU A CD2 1 ATOM 7787 N N . THR A 1 966 ? 64.792 55.141 -3.249 1.00 10.50 ? 966 THR A N 1 ATOM 7788 C CA . THR A 1 966 ? 65.998 55.241 -2.401 1.00 10.66 ? 966 THR A CA 1 ATOM 7789 C C . THR A 1 966 ? 66.676 56.555 -2.585 1.00 10.15 ? 966 THR A C 1 ATOM 7790 O O . THR A 1 966 ? 66.662 57.092 -3.708 1.00 11.08 ? 966 THR A O 1 ATOM 7791 C CB . THR A 1 966 ? 66.993 54.144 -2.806 1.00 12.39 ? 966 THR A CB 1 ATOM 7792 O OG1 . THR A 1 966 ? 67.048 54.021 -4.229 1.00 11.71 ? 966 THR A OG1 1 ATOM 7793 C CG2 . THR A 1 966 ? 66.551 52.766 -2.260 1.00 11.99 ? 966 THR A CG2 1 ATOM 7794 N N . LYS A 1 967 ? 67.358 57.010 -1.540 1.00 11.41 ? 967 LYS A N 1 ATOM 7795 C CA . LYS A 1 967 ? 68.170 58.233 -1.590 1.00 11.54 ? 967 LYS A CA 1 ATOM 7796 C C . LYS A 1 967 ? 69.590 57.795 -2.118 1.00 12.17 ? 967 LYS A C 1 ATOM 7797 O O . LYS A 1 967 ? 69.891 56.602 -2.265 1.00 12.42 ? 967 LYS A O 1 ATOM 7798 C CB . LYS A 1 967 ? 68.280 58.871 -0.200 1.00 14.57 ? 967 LYS A CB 1 ATOM 7799 C CG . LYS A 1 967 ? 66.918 59.499 0.243 1.00 19.27 ? 967 LYS A CG 1 ATOM 7800 C CD . LYS A 1 967 ? 67.037 60.420 1.492 1.00 22.04 ? 967 LYS A CD 1 ATOM 7801 C CE . LYS A 1 967 ? 65.681 61.048 1.807 1.00 29.80 ? 967 LYS A CE 1 ATOM 7802 N NZ . LYS A 1 967 ? 65.408 60.961 3.262 1.00 39.61 ? 967 LYS A NZ 1 ATOM 7803 N N . SER A 1 968 ? 70.423 58.798 -2.416 1.00 13.00 ? 968 SER A N 1 ATOM 7804 C CA . SER A 1 968 ? 71.699 58.498 -3.084 1.00 13.72 ? 968 SER A CA 1 ATOM 7805 C C . SER A 1 968 ? 72.688 57.677 -2.271 1.00 14.73 ? 968 SER A C 1 ATOM 7806 O O . SER A 1 968 ? 73.512 56.984 -2.908 1.00 17.91 ? 968 SER A O 1 ATOM 7807 C CB . SER A 1 968 ? 72.362 59.792 -3.572 1.00 16.79 ? 968 SER A CB 1 ATOM 7808 O OG . SER A 1 968 ? 72.587 60.649 -2.516 1.00 22.58 ? 968 SER A OG 1 ATOM 7809 N N . SER A 1 969 ? 72.545 57.684 -0.952 1.00 16.08 ? 969 SER A N 1 ATOM 7810 C CA . SER A 1 969 ? 73.473 56.894 -0.100 1.00 17.38 ? 969 SER A CA 1 ATOM 7811 C C . SER A 1 969 ? 73.224 55.377 -0.129 1.00 18.29 ? 969 SER A C 1 ATOM 7812 O O . SER A 1 969 ? 74.062 54.620 0.362 1.00 18.54 ? 969 SER A O 1 ATOM 7813 C CB . SER A 1 969 ? 73.427 57.436 1.322 1.00 21.97 ? 969 SER A CB 1 ATOM 7814 O OG . SER A 1 969 ? 72.113 57.302 1.802 1.00 32.56 ? 969 SER A OG 1 ATOM 7815 N N . ALA A 1 970 ? 72.102 54.887 -0.674 1.00 13.93 ? 970 ALA A N 1 ATOM 7816 C CA . ALA A 1 970 ? 71.837 53.463 -0.753 1.00 13.33 ? 970 ALA A CA 1 ATOM 7817 C C . ALA A 1 970 ? 72.655 52.753 -1.807 1.00 16.39 ? 970 ALA A C 1 ATOM 7818 O O . ALA A 1 970 ? 72.641 53.105 -3.010 1.00 15.49 ? 970 ALA A O 1 ATOM 7819 C CB . ALA A 1 970 ? 70.328 53.187 -1.004 1.00 16.11 ? 970 ALA A CB 1 ATOM 7820 N N A LYS A 1 971 ? 73.431 51.744 -1.356 0.50 16.75 ? 971 LYS A N 1 ATOM 7821 N N B LYS A 1 971 ? 73.431 51.744 -1.356 0.50 17.09 ? 971 LYS A N 1 ATOM 7822 C CA A LYS A 1 971 ? 74.225 50.962 -2.304 0.50 18.03 ? 971 LYS A CA 1 ATOM 7823 C CA B LYS A 1 971 ? 74.225 50.962 -2.304 0.50 18.49 ? 971 LYS A CA 1 ATOM 7824 C C A LYS A 1 971 ? 73.336 50.342 -3.388 0.50 17.30 ? 971 LYS A C 1 ATOM 7825 C C B LYS A 1 971 ? 73.336 50.342 -3.388 0.50 17.65 ? 971 LYS A C 1 ATOM 7826 O O A LYS A 1 971 ? 73.719 50.306 -4.553 0.50 20.02 ? 971 LYS A O 1 ATOM 7827 O O B LYS A 1 971 ? 73.719 50.306 -4.553 0.50 20.34 ? 971 LYS A O 1 ATOM 7828 C CB A LYS A 1 971 ? 74.975 49.846 -1.539 0.50 20.83 ? 971 LYS A CB 1 ATOM 7829 C CB B LYS A 1 971 ? 74.975 49.846 -1.539 0.50 21.73 ? 971 LYS A CB 1 ATOM 7830 C CG A LYS A 1 971 ? 75.836 48.943 -2.409 0.50 26.53 ? 971 LYS A CG 1 ATOM 7831 C CG B LYS A 1 971 ? 75.766 48.890 -2.418 0.50 27.63 ? 971 LYS A CG 1 ATOM 7832 C CD A LYS A 1 971 ? 76.891 48.218 -1.517 0.50 29.92 ? 971 LYS A CD 1 ATOM 7833 C CD B LYS A 1 971 ? 76.899 48.228 -1.574 0.50 31.49 ? 971 LYS A CD 1 ATOM 7834 C CE A LYS A 1 971 ? 77.599 47.096 -2.297 0.50 32.33 ? 971 LYS A CE 1 ATOM 7835 C CE B LYS A 1 971 ? 76.911 48.776 -0.136 0.50 34.08 ? 971 LYS A CE 1 ATOM 7836 N NZ A LYS A 1 971 ? 78.139 47.507 -3.637 0.50 33.43 ? 971 LYS A NZ 1 ATOM 7837 N NZ B LYS A 1 971 ? 77.358 50.205 -0.013 0.50 37.35 ? 971 LYS A NZ 1 ATOM 7838 N N . THR A 1 972 ? 72.175 49.806 -2.984 1.00 17.75 ? 972 THR A N 1 ATOM 7839 C CA . THR A 1 972 ? 71.251 49.224 -3.940 1.00 16.61 ? 972 THR A CA 1 ATOM 7840 C C . THR A 1 972 ? 70.100 50.229 -4.203 1.00 13.70 ? 972 THR A C 1 ATOM 7841 O O . THR A 1 972 ? 69.309 50.501 -3.311 1.00 15.54 ? 972 THR A O 1 ATOM 7842 C CB . THR A 1 972 ? 70.667 47.882 -3.468 1.00 18.96 ? 972 THR A CB 1 ATOM 7843 O OG1 . THR A 1 972 ? 71.753 46.959 -3.231 1.00 22.02 ? 972 THR A OG1 1 ATOM 7844 C CG2 . THR A 1 972 ? 69.823 47.237 -4.575 1.00 17.92 ? 972 THR A CG2 1 ATOM 7845 N N . GLN A 1 973 ? 70.085 50.829 -5.396 1.00 12.04 ? 973 GLN A N 1 ATOM 7846 C CA . GLN A 1 973 ? 68.998 51.771 -5.748 1.00 12.63 ? 973 GLN A CA 1 ATOM 7847 C C . GLN A 1 973 ? 67.754 50.963 -6.091 1.00 12.76 ? 973 GLN A C 1 ATOM 7848 O O . GLN A 1 973 ? 67.815 49.903 -6.674 1.00 13.21 ? 973 GLN A O 1 ATOM 7849 C CB . GLN A 1 973 ? 69.450 52.638 -6.917 1.00 12.20 ? 973 GLN A CB 1 ATOM 7850 C CG . GLN A 1 973 ? 70.562 53.619 -6.465 1.00 11.37 ? 973 GLN A CG 1 ATOM 7851 C CD . GLN A 1 973 ? 70.124 54.643 -5.453 1.00 12.43 ? 973 GLN A CD 1 ATOM 7852 O OE1 . GLN A 1 973 ? 70.752 54.853 -4.360 1.00 14.00 ? 973 GLN A OE1 1 ATOM 7853 N NE2 . GLN A 1 973 ? 69.044 55.344 -5.786 1.00 10.41 ? 973 GLN A NE2 1 ATOM 7854 N N . ARG A 1 974 ? 66.598 51.558 -5.784 1.00 12.78 ? 974 ARG A N 1 ATOM 7855 C CA . ARG A 1 974 ? 65.309 50.935 -6.086 1.00 12.20 ? 974 ARG A CA 1 ATOM 7856 C C . ARG A 1 974 ? 64.380 51.934 -6.751 1.00 9.80 ? 974 ARG A C 1 ATOM 7857 O O . ARG A 1 974 ? 64.297 53.083 -6.280 1.00 10.50 ? 974 ARG A O 1 ATOM 7858 C CB . ARG A 1 974 ? 64.625 50.436 -4.819 1.00 11.79 ? 974 ARG A CB 1 ATOM 7859 C CG . ARG A 1 974 ? 65.462 49.316 -4.092 1.00 13.77 ? 974 ARG A CG 1 ATOM 7860 C CD . ARG A 1 974 ? 64.955 49.034 -2.657 1.00 16.39 ? 974 ARG A CD 1 ATOM 7861 N NE . ARG A 1 974 ? 63.700 48.310 -2.706 1.00 23.10 ? 974 ARG A NE 1 ATOM 7862 C CZ . ARG A 1 974 ? 62.548 48.727 -2.198 1.00 20.03 ? 974 ARG A CZ 1 ATOM 7863 N NH1 . ARG A 1 974 ? 62.423 49.878 -1.567 1.00 21.59 ? 974 ARG A NH1 1 ATOM 7864 N NH2 . ARG A 1 974 ? 61.500 47.944 -2.354 1.00 19.04 ? 974 ARG A NH2 1 ATOM 7865 N N . VAL A 1 975 ? 63.723 51.491 -7.809 1.00 9.86 ? 975 VAL A N 1 ATOM 7866 C CA . VAL A 1 975 ? 62.759 52.352 -8.528 1.00 11.29 ? 975 VAL A CA 1 ATOM 7867 C C . VAL A 1 975 ? 61.461 51.595 -8.629 1.00 10.72 ? 975 VAL A C 1 ATOM 7868 O O . VAL A 1 975 ? 61.415 50.421 -9.081 1.00 10.74 ? 975 VAL A O 1 ATOM 7869 C CB . VAL A 1 975 ? 63.279 52.711 -9.964 1.00 11.41 ? 975 VAL A CB 1 ATOM 7870 C CG1 . VAL A 1 975 ? 62.323 53.730 -10.636 1.00 11.09 ? 975 VAL A CG1 1 ATOM 7871 C CG2 . VAL A 1 975 ? 64.620 53.469 -9.836 1.00 13.46 ? 975 VAL A CG2 1 ATOM 7872 N N . GLY A 1 976 ? 60.392 52.299 -8.235 1.00 9.91 ? 976 GLY A N 1 ATOM 7873 C CA . GLY A 1 976 ? 59.051 51.717 -8.257 1.00 9.67 ? 976 GLY A CA 1 ATOM 7874 C C . GLY A 1 976 ? 58.229 52.216 -9.436 1.00 7.44 ? 976 GLY A C 1 ATOM 7875 O O . GLY A 1 976 ? 58.284 53.409 -9.846 1.00 9.09 ? 976 GLY A O 1 ATOM 7876 N N . TYR A 1 977 ? 57.471 51.306 -9.990 1.00 8.55 ? 977 TYR A N 1 ATOM 7877 C CA . TYR A 1 977 ? 56.570 51.618 -11.109 1.00 8.26 ? 977 TYR A CA 1 ATOM 7878 C C . TYR A 1 977 ? 55.155 51.084 -10.844 1.00 8.28 ? 977 TYR A C 1 ATOM 7879 O O . TYR A 1 977 ? 54.994 49.952 -10.342 1.00 9.21 ? 977 TYR A O 1 ATOM 7880 C CB . TYR A 1 977 ? 57.012 50.886 -12.393 1.00 9.03 ? 977 TYR A CB 1 ATOM 7881 C CG . TYR A 1 977 ? 58.415 51.245 -12.805 1.00 8.54 ? 977 TYR A CG 1 ATOM 7882 C CD1 . TYR A 1 977 ? 59.519 50.522 -12.333 1.00 10.11 ? 977 TYR A CD1 1 ATOM 7883 C CD2 . TYR A 1 977 ? 58.632 52.318 -13.672 1.00 10.07 ? 977 TYR A CD2 1 ATOM 7884 C CE1 . TYR A 1 977 ? 60.816 50.886 -12.746 1.00 11.24 ? 977 TYR A CE1 1 ATOM 7885 C CE2 . TYR A 1 977 ? 59.892 52.683 -14.086 1.00 11.31 ? 977 TYR A CE2 1 ATOM 7886 C CZ . TYR A 1 977 ? 60.966 51.969 -13.615 1.00 10.38 ? 977 TYR A CZ 1 ATOM 7887 O OH . TYR A 1 977 ? 62.237 52.383 -14.040 1.00 11.73 ? 977 TYR A OH 1 ATOM 7888 N N . VAL A 1 978 ? 54.132 51.901 -11.154 1.00 7.39 ? 978 VAL A N 1 ATOM 7889 C CA . VAL A 1 978 ? 52.753 51.390 -11.137 1.00 7.48 ? 978 VAL A CA 1 ATOM 7890 C C . VAL A 1 978 ? 52.327 51.363 -12.613 1.00 8.13 ? 978 VAL A C 1 ATOM 7891 O O . VAL A 1 978 ? 52.394 52.398 -13.293 1.00 9.34 ? 978 VAL A O 1 ATOM 7892 C CB . VAL A 1 978 ? 51.779 52.274 -10.333 1.00 8.12 ? 978 VAL A CB 1 ATOM 7893 C CG1 . VAL A 1 978 ? 50.324 51.741 -10.508 1.00 9.58 ? 978 VAL A CG1 1 ATOM 7894 C CG2 . VAL A 1 978 ? 52.174 52.246 -8.826 1.00 9.38 ? 978 VAL A CG2 1 ATOM 7895 N N A LEU A 1 979 ? 51.912 50.189 -13.085 0.50 7.42 ? 979 LEU A N 1 ATOM 7896 N N B LEU A 1 979 ? 51.912 50.189 -13.085 0.50 8.89 ? 979 LEU A N 1 ATOM 7897 C CA A LEU A 1 979 ? 51.500 49.966 -14.467 0.50 9.29 ? 979 LEU A CA 1 ATOM 7898 C CA B LEU A 1 979 ? 51.500 49.966 -14.467 0.50 11.28 ? 979 LEU A CA 1 ATOM 7899 C C A LEU A 1 979 ? 50.025 49.707 -14.488 0.50 8.53 ? 979 LEU A C 1 ATOM 7900 C C B LEU A 1 979 ? 50.025 49.707 -14.488 0.50 10.34 ? 979 LEU A C 1 ATOM 7901 O O A LEU A 1 979 ? 49.517 48.814 -13.765 0.50 11.85 ? 979 LEU A O 1 ATOM 7902 O O B LEU A 1 979 ? 49.517 48.814 -13.765 0.50 12.68 ? 979 LEU A O 1 ATOM 7903 C CB A LEU A 1 979 ? 52.168 48.716 -15.027 0.50 11.76 ? 979 LEU A CB 1 ATOM 7904 C CB B LEU A 1 979 ? 52.168 48.716 -15.027 0.50 16.99 ? 979 LEU A CB 1 ATOM 7905 C CG A LEU A 1 979 ? 53.249 48.542 -16.101 0.50 22.12 ? 979 LEU A CG 1 ATOM 7906 C CG B LEU A 1 979 ? 53.187 48.535 -16.159 0.50 27.15 ? 979 LEU A CG 1 ATOM 7907 C CD1 A LEU A 1 979 ? 53.119 47.140 -16.756 0.50 15.94 ? 979 LEU A CD1 1 ATOM 7908 C CD1 B LEU A 1 979 ? 54.209 49.704 -16.139 0.50 27.85 ? 979 LEU A CD1 1 ATOM 7909 C CD2 A LEU A 1 979 ? 53.095 49.570 -17.148 0.50 13.72 ? 979 LEU A CD2 1 ATOM 7910 C CD2 B LEU A 1 979 ? 53.917 47.264 -15.987 0.50 27.37 ? 979 LEU A CD2 1 ATOM 7911 N N . HIS A 1 980 ? 49.313 50.463 -15.295 1.00 8.70 ? 980 HIS A N 1 ATOM 7912 C CA . HIS A 1 980 ? 47.860 50.305 -15.427 1.00 9.57 ? 980 HIS A CA 1 ATOM 7913 C C . HIS A 1 980 ? 47.485 50.011 -16.881 1.00 9.65 ? 980 HIS A C 1 ATOM 7914 O O . HIS A 1 980 ? 47.936 50.736 -17.773 1.00 11.46 ? 980 HIS A O 1 ATOM 7915 C CB . HIS A 1 980 ? 47.058 51.585 -15.015 1.00 10.25 ? 980 HIS A CB 1 ATOM 7916 C CG . HIS A 1 980 ? 45.575 51.363 -15.109 1.00 10.27 ? 980 HIS A CG 1 ATOM 7917 N ND1 . HIS A 1 980 ? 44.699 51.952 -16.012 1.00 14.02 ? 980 HIS A ND1 1 ATOM 7918 C CD2 . HIS A 1 980 ? 44.840 50.487 -14.408 1.00 7.90 ? 980 HIS A CD2 1 ATOM 7919 C CE1 . HIS A 1 980 ? 43.485 51.435 -15.840 1.00 8.41 ? 980 HIS A CE1 1 ATOM 7920 N NE2 . HIS A 1 980 ? 43.557 50.532 -14.884 1.00 14.22 ? 980 HIS A NE2 1 ATOM 7921 N N . ARG A 1 981 ? 46.678 48.977 -17.116 1.00 8.49 ? 981 ARG A N 1 ATOM 7922 C CA . ARG A 1 981 ? 46.148 48.780 -18.471 1.00 9.22 ? 981 ARG A CA 1 ATOM 7923 C C . ARG A 1 981 ? 44.665 48.978 -18.419 1.00 7.92 ? 981 ARG A C 1 ATOM 7924 O O . ARG A 1 981 ? 43.990 48.316 -17.617 1.00 9.86 ? 981 ARG A O 1 ATOM 7925 C CB . ARG A 1 981 ? 46.445 47.386 -19.034 1.00 11.49 ? 981 ARG A CB 1 ATOM 7926 C CG . ARG A 1 981 ? 46.207 47.356 -20.621 1.00 13.92 ? 981 ARG A CG 1 ATOM 7927 C CD . ARG A 1 981 ? 46.220 45.968 -21.351 1.00 20.46 ? 981 ARG A CD 1 ATOM 7928 N NE . ARG A 1 981 ? 47.465 45.287 -21.134 1.00 22.81 ? 981 ARG A NE 1 ATOM 7929 C CZ . ARG A 1 981 ? 48.500 45.321 -21.988 1.00 21.32 ? 981 ARG A CZ 1 ATOM 7930 N NH1 . ARG A 1 981 ? 48.440 46.038 -23.134 1.00 19.67 ? 981 ARG A NH1 1 ATOM 7931 N NH2 . ARG A 1 981 ? 49.582 44.568 -21.719 1.00 21.17 ? 981 ARG A NH2 1 ATOM 7932 N N . THR A 1 982 ? 44.176 49.877 -19.261 1.00 9.46 ? 982 THR A N 1 ATOM 7933 C CA . THR A 1 982 ? 42.717 50.085 -19.345 1.00 9.72 ? 982 THR A CA 1 ATOM 7934 C C . THR A 1 982 ? 42.206 49.059 -20.374 1.00 10.32 ? 982 THR A C 1 ATOM 7935 O O . THR A 1 982 ? 42.932 48.119 -20.732 1.00 12.63 ? 982 THR A O 1 ATOM 7936 C CB . THR A 1 982 ? 42.416 51.534 -19.787 1.00 9.73 ? 982 THR A CB 1 ATOM 7937 O OG1 . THR A 1 982 ? 41.033 51.790 -19.637 1.00 11.47 ? 982 THR A OG1 1 ATOM 7938 C CG2 . THR A 1 982 ? 42.889 51.845 -21.227 1.00 11.40 ? 982 THR A CG2 1 ATOM 7939 N N . ASN A 1 983 ? 40.941 49.153 -20.708 1.00 9.00 ? 983 ASN A N 1 ATOM 7940 C CA . ASN A 1 983 ? 40.369 48.248 -21.740 1.00 9.47 ? 983 ASN A CA 1 ATOM 7941 C C . ASN A 1 983 ? 39.633 49.135 -22.755 1.00 9.82 ? 983 ASN A C 1 ATOM 7942 O O . ASN A 1 983 ? 38.722 49.882 -22.384 1.00 11.48 ? 983 ASN A O 1 ATOM 7943 C CB . ASN A 1 983 ? 39.374 47.239 -21.130 1.00 9.30 ? 983 ASN A CB 1 ATOM 7944 C CG . ASN A 1 983 ? 38.862 46.265 -22.184 1.00 9.01 ? 983 ASN A CG 1 ATOM 7945 O OD1 . ASN A 1 983 ? 39.606 45.375 -22.578 1.00 12.17 ? 983 ASN A OD1 1 ATOM 7946 N ND2 . ASN A 1 983 ? 37.654 46.505 -22.664 1.00 11.09 ? 983 ASN A ND2 1 ATOM 7947 N N . LEU A 1 984 ? 40.079 49.016 -23.987 1.00 9.94 ? 984 LEU A N 1 ATOM 7948 C CA . LEU A 1 984 ? 39.508 49.790 -25.082 1.00 9.78 ? 984 LEU A CA 1 ATOM 7949 C C . LEU A 1 984 ? 38.679 48.899 -25.988 1.00 11.85 ? 984 LEU A C 1 ATOM 7950 O O . LEU A 1 984 ? 38.995 47.732 -26.205 1.00 13.75 ? 984 LEU A O 1 ATOM 7951 C CB . LEU A 1 984 ? 40.634 50.430 -25.905 1.00 11.60 ? 984 LEU A CB 1 ATOM 7952 C CG . LEU A 1 984 ? 41.585 51.311 -25.054 1.00 12.38 ? 984 LEU A CG 1 ATOM 7953 C CD1 . LEU A 1 984 ? 42.744 51.797 -25.975 1.00 14.21 ? 984 LEU A CD1 1 ATOM 7954 C CD2 . LEU A 1 984 ? 40.837 52.485 -24.424 1.00 13.09 ? 984 LEU A CD2 1 ATOM 7955 N N . MET A 1 985 ? 37.622 49.460 -26.539 1.00 12.35 ? 985 MET A N 1 ATOM 7956 C CA . MET A 1 985 ? 36.790 48.622 -27.433 1.00 15.88 ? 985 MET A CA 1 ATOM 7957 C C . MET A 1 985 ? 37.468 48.263 -28.714 1.00 19.44 ? 985 MET A C 1 ATOM 7958 O O . MET A 1 985 ? 38.236 49.033 -29.298 1.00 17.05 ? 985 MET A O 1 ATOM 7959 C CB . MET A 1 985 ? 35.518 49.350 -27.786 1.00 17.57 ? 985 MET A CB 1 ATOM 7960 C CG . MET A 1 985 ? 34.603 49.450 -26.605 1.00 19.05 ? 985 MET A CG 1 ATOM 7961 S SD . MET A 1 985 ? 32.899 49.600 -27.093 1.00 21.74 ? 985 MET A SD 1 ATOM 7962 C CE . MET A 1 985 ? 33.004 51.138 -27.887 1.00 19.84 ? 985 MET A CE 1 ATOM 7963 N N . GLN A 1 986 ? 37.163 47.050 -29.159 1.00 19.02 ? 986 GLN A N 1 ATOM 7964 C CA . GLN A 1 986 ? 37.671 46.563 -30.455 1.00 18.08 ? 986 GLN A CA 1 ATOM 7965 C C . GLN A 1 986 ? 36.643 47.045 -31.466 1.00 17.57 ? 986 GLN A C 1 ATOM 7966 O O . GLN A 1 986 ? 35.469 46.658 -31.354 1.00 17.23 ? 986 GLN A O 1 ATOM 7967 C CB . GLN A 1 986 ? 37.685 45.022 -30.467 1.00 22.31 ? 986 GLN A CB 1 ATOM 7968 C CG . GLN A 1 986 ? 38.751 44.335 -29.586 1.00 28.13 ? 986 GLN A CG 1 ATOM 7969 C CD . GLN A 1 986 ? 40.159 44.622 -30.072 1.00 34.31 ? 986 GLN A CD 1 ATOM 7970 O OE1 . GLN A 1 986 ? 41.068 44.812 -29.260 1.00 42.17 ? 986 GLN A OE1 1 ATOM 7971 N NE2 . GLN A 1 986 ? 40.362 44.651 -31.408 1.00 35.81 ? 986 GLN A NE2 1 ATOM 7972 N N . CYS A 1 987 ? 37.059 47.898 -32.414 1.00 18.19 ? 987 CYS A N 1 ATOM 7973 C CA . CYS A 1 987 ? 36.108 48.397 -33.399 1.00 19.20 ? 987 CYS A CA 1 ATOM 7974 C C . CYS A 1 987 ? 36.559 48.183 -34.833 1.00 22.49 ? 987 CYS A C 1 ATOM 7975 O O . CYS A 1 987 ? 35.997 48.823 -35.742 1.00 24.64 ? 987 CYS A O 1 ATOM 7976 C CB . CYS A 1 987 ? 35.795 49.877 -33.164 1.00 20.36 ? 987 CYS A CB 1 ATOM 7977 S SG . CYS A 1 987 ? 35.187 50.291 -31.472 1.00 22.55 ? 987 CYS A SG 1 ATOM 7978 N N . GLY A 1 988 ? 37.532 47.296 -35.041 1.00 19.81 ? 988 GLY A N 1 ATOM 7979 C CA . GLY A 1 988 ? 37.947 47.032 -36.413 1.00 26.32 ? 988 GLY A CA 1 ATOM 7980 C C . GLY A 1 988 ? 39.188 47.714 -36.912 1.00 30.41 ? 988 GLY A C 1 ATOM 7981 O O . GLY A 1 988 ? 39.503 47.633 -38.121 1.00 30.21 ? 988 GLY A O 1 ATOM 7982 N N . THR A 1 989 ? 39.901 48.396 -36.025 1.00 29.26 ? 989 THR A N 1 ATOM 7983 C CA . THR A 1 989 ? 41.126 49.038 -36.459 1.00 30.44 ? 989 THR A CA 1 ATOM 7984 C C . THR A 1 989 ? 42.247 48.066 -36.227 1.00 34.25 ? 989 THR A C 1 ATOM 7985 O O . THR A 1 989 ? 42.496 47.651 -35.094 1.00 33.11 ? 989 THR A O 1 ATOM 7986 C CB . THR A 1 989 ? 41.382 50.295 -35.678 1.00 31.10 ? 989 THR A CB 1 ATOM 7987 O OG1 . THR A 1 989 ? 40.246 51.147 -35.827 1.00 32.85 ? 989 THR A OG1 1 ATOM 7988 C CG2 . THR A 1 989 ? 42.615 51.007 -36.214 1.00 32.83 ? 989 THR A CG2 1 ATOM 7989 N N . PRO A 1 990 ? 42.945 47.675 -37.310 1.00 34.05 ? 990 PRO A N 1 ATOM 7990 C CA . PRO A 1 990 ? 44.042 46.726 -37.123 1.00 36.00 ? 990 PRO A CA 1 ATOM 7991 C C . PRO A 1 990 ? 45.065 47.186 -36.072 1.00 39.32 ? 990 PRO A C 1 ATOM 7992 O O . PRO A 1 990 ? 45.658 46.327 -35.406 1.00 41.59 ? 990 PRO A O 1 ATOM 7993 C CB . PRO A 1 990 ? 44.657 46.623 -38.521 1.00 36.87 ? 990 PRO A CB 1 ATOM 7994 C CG . PRO A 1 990 ? 43.520 46.903 -39.442 1.00 34.72 ? 990 PRO A CG 1 ATOM 7995 C CD . PRO A 1 990 ? 42.800 48.058 -38.728 1.00 35.61 ? 990 PRO A CD 1 ATOM 7996 N N . GLU A 1 991 ? 45.235 48.502 -35.867 1.00 41.13 ? 991 GLU A N 1 ATOM 7997 C CA . GLU A 1 991 ? 46.246 49.028 -34.909 1.00 46.41 ? 991 GLU A CA 1 ATOM 7998 C C . GLU A 1 991 ? 47.247 47.918 -34.482 1.00 47.64 ? 991 GLU A C 1 ATOM 7999 O O . GLU A 1 991 ? 46.902 46.967 -33.752 1.00 50.18 ? 991 GLU A O 1 ATOM 8000 C CB . GLU A 1 991 ? 45.573 49.732 -33.688 1.00 46.76 ? 991 GLU A CB 1 ATOM 8001 C CG . GLU A 1 991 ? 44.894 51.083 -34.101 1.00 48.33 ? 991 GLU A CG 1 ATOM 8002 C CD . GLU A 1 991 ? 44.164 51.886 -32.980 1.00 50.56 ? 991 GLU A CD 1 ATOM 8003 O OE1 . GLU A 1 991 ? 43.398 51.306 -32.157 1.00 45.43 ? 991 GLU A OE1 1 ATOM 8004 O OE2 . GLU A 1 991 ? 44.335 53.138 -32.964 1.00 49.17 ? 991 GLU A OE2 1 ATOM 8005 N N . GLU A 1 992 ? 48.487 48.040 -34.952 1.00 46.60 ? 992 GLU A N 1 ATOM 8006 C CA . GLU A 1 992 ? 49.484 47.003 -34.702 1.00 47.42 ? 992 GLU A CA 1 ATOM 8007 C C . GLU A 1 992 ? 50.806 47.322 -33.966 1.00 44.47 ? 992 GLU A C 1 ATOM 8008 O O . GLU A 1 992 ? 50.792 47.789 -32.853 1.00 43.28 ? 992 GLU A O 1 ATOM 8009 C CB . GLU A 1 992 ? 49.792 46.343 -36.051 1.00 49.57 ? 992 GLU A CB 1 ATOM 8010 C CG . GLU A 1 992 ? 48.522 45.866 -36.806 1.00 50.69 ? 992 GLU A CG 1 ATOM 8011 C CD . GLU A 1 992 ? 47.827 44.688 -36.121 1.00 51.35 ? 992 GLU A CD 1 ATOM 8012 O OE1 . GLU A 1 992 ? 46.959 44.032 -36.755 1.00 53.07 ? 992 GLU A OE1 1 ATOM 8013 O OE2 . GLU A 1 992 ? 48.143 44.409 -34.941 1.00 52.78 ? 992 GLU A OE2 1 ATOM 8014 N N . HIS A 1 993 ? 51.936 47.046 -34.614 1.00 42.52 ? 993 HIS A N 1 ATOM 8015 C CA . HIS A 1 993 ? 53.309 47.249 -34.076 1.00 42.11 ? 993 HIS A CA 1 ATOM 8016 C C . HIS A 1 993 ? 53.670 48.171 -32.885 1.00 39.58 ? 993 HIS A C 1 ATOM 8017 O O . HIS A 1 993 ? 53.812 49.409 -33.028 1.00 39.66 ? 993 HIS A O 1 ATOM 8018 C CB . HIS A 1 993 ? 54.271 47.616 -35.233 1.00 42.87 ? 993 HIS A CB 1 ATOM 8019 C CG . HIS A 1 993 ? 53.903 48.881 -35.936 1.00 43.90 ? 993 HIS A CG 1 ATOM 8020 N ND1 . HIS A 1 993 ? 52.767 48.996 -36.714 1.00 47.46 ? 993 HIS A ND1 1 ATOM 8021 C CD2 . HIS A 1 993 ? 54.464 50.113 -35.905 1.00 44.58 ? 993 HIS A CD2 1 ATOM 8022 C CE1 . HIS A 1 993 ? 52.641 50.248 -37.126 1.00 47.73 ? 993 HIS A CE1 1 ATOM 8023 N NE2 . HIS A 1 993 ? 53.657 50.946 -36.649 1.00 47.27 ? 993 HIS A NE2 1 ATOM 8024 N N . THR A 1 994 ? 53.843 47.551 -31.713 1.00 36.35 ? 994 THR A N 1 ATOM 8025 C CA . THR A 1 994 ? 54.284 48.265 -30.515 1.00 29.12 ? 994 THR A CA 1 ATOM 8026 C C . THR A 1 994 ? 55.290 47.343 -29.827 1.00 28.32 ? 994 THR A C 1 ATOM 8027 O O . THR A 1 994 ? 55.354 46.147 -30.107 1.00 30.84 ? 994 THR A O 1 ATOM 8028 C CB . THR A 1 994 ? 53.132 48.578 -29.554 1.00 25.41 ? 994 THR A CB 1 ATOM 8029 O OG1 . THR A 1 994 ? 52.459 47.366 -29.203 1.00 27.06 ? 994 THR A OG1 1 ATOM 8030 C CG2 . THR A 1 994 ? 52.133 49.507 -30.225 1.00 23.40 ? 994 THR A CG2 1 ATOM 8031 N N . GLN A 1 995 ? 56.058 47.869 -28.886 1.00 23.23 ? 995 GLN A N 1 ATOM 8032 C CA . GLN A 1 995 ? 57.050 47.048 -28.237 1.00 22.32 ? 995 GLN A CA 1 ATOM 8033 C C . GLN A 1 995 ? 56.608 46.717 -26.842 1.00 19.42 ? 995 GLN A C 1 ATOM 8034 O O . GLN A 1 995 ? 55.928 47.504 -26.175 1.00 19.82 ? 995 GLN A O 1 ATOM 8035 C CB . GLN A 1 995 ? 58.355 47.820 -28.137 1.00 20.67 ? 995 GLN A CB 1 ATOM 8036 C CG . GLN A 1 995 ? 58.812 48.289 -29.501 1.00 27.32 ? 995 GLN A CG 1 ATOM 8037 C CD . GLN A 1 995 ? 59.676 49.516 -29.418 1.00 33.09 ? 995 GLN A CD 1 ATOM 8038 O OE1 . GLN A 1 995 ? 59.181 50.649 -29.276 1.00 23.54 ? 995 GLN A OE1 1 ATOM 8039 N NE2 . GLN A 1 995 ? 60.988 49.304 -29.484 1.00 36.77 ? 995 GLN A NE2 1 ATOM 8040 N N . LYS A 1 996 ? 57.064 45.572 -26.376 1.00 17.70 ? 996 LYS A N 1 ATOM 8041 C CA . LYS A 1 996 ? 56.795 45.144 -25.016 1.00 18.34 ? 996 LYS A CA 1 ATOM 8042 C C . LYS A 1 996 ? 57.504 46.116 -24.075 1.00 16.37 ? 996 LYS A C 1 ATOM 8043 O O . LYS A 1 996 ? 58.666 46.494 -24.281 1.00 18.08 ? 996 LYS A O 1 ATOM 8044 C CB . LYS A 1 996 ? 57.356 43.699 -24.823 1.00 21.28 ? 996 LYS A CB 1 ATOM 8045 C CG . LYS A 1 996 ? 57.099 43.088 -23.454 1.00 26.23 ? 996 LYS A CG 1 ATOM 8046 C CD . LYS A 1 996 ? 57.641 41.606 -23.450 1.00 29.34 ? 996 LYS A CD 1 ATOM 8047 C CE . LYS A 1 996 ? 57.574 40.966 -22.051 1.00 34.64 ? 996 LYS A CE 1 ATOM 8048 N NZ . LYS A 1 996 ? 57.733 39.491 -22.210 1.00 41.42 ? 996 LYS A NZ 1 ATOM 8049 N N . LEU A 1 997 ? 56.792 46.523 -23.031 1.00 16.19 ? 997 LEU A N 1 ATOM 8050 C CA . LEU A 1 997 ? 57.401 47.414 -22.056 1.00 16.01 ? 997 LEU A CA 1 ATOM 8051 C C . LEU A 1 997 ? 57.739 46.602 -20.804 1.00 13.60 ? 997 LEU A C 1 ATOM 8052 O O . LEU A 1 997 ? 56.825 46.058 -20.160 1.00 16.50 ? 997 LEU A O 1 ATOM 8053 C CB . LEU A 1 997 ? 56.391 48.503 -21.695 1.00 17.29 ? 997 LEU A CB 1 ATOM 8054 C CG . LEU A 1 997 ? 56.817 49.356 -20.493 1.00 18.01 ? 997 LEU A CG 1 ATOM 8055 C CD1 . LEU A 1 997 ? 58.069 50.099 -20.809 1.00 20.41 ? 997 LEU A CD1 1 ATOM 8056 C CD2 . LEU A 1 997 ? 55.706 50.336 -20.178 1.00 21.67 ? 997 LEU A CD2 1 ATOM 8057 N N . ASP A 1 998 ? 59.027 46.545 -20.506 1.00 14.23 ? 998 ASP A N 1 ATOM 8058 C CA . ASP A 1 998 ? 59.511 45.893 -19.293 1.00 15.84 ? 998 ASP A CA 1 ATOM 8059 C C . ASP A 1 998 ? 60.097 47.008 -18.437 1.00 14.04 ? 998 ASP A C 1 ATOM 8060 O O . ASP A 1 998 ? 61.213 47.480 -18.640 1.00 14.39 ? 998 ASP A O 1 ATOM 8061 C CB . ASP A 1 998 ? 60.577 44.830 -19.635 1.00 16.50 ? 998 ASP A CB 1 ATOM 8062 C CG . ASP A 1 998 ? 61.249 44.292 -18.407 1.00 20.04 ? 998 ASP A CG 1 ATOM 8063 O OD1 . ASP A 1 998 ? 62.289 43.626 -18.586 1.00 18.77 ? 998 ASP A OD1 1 ATOM 8064 O OD2 . ASP A 1 998 ? 60.763 44.529 -17.267 1.00 17.42 ? 998 ASP A OD2 1 ATOM 8065 N N . VAL A 1 999 ? 59.319 47.446 -17.451 1.00 14.11 ? 999 VAL A N 1 ATOM 8066 C CA . VAL A 1 999 ? 59.810 48.562 -16.651 1.00 12.67 ? 999 VAL A CA 1 ATOM 8067 C C . VAL A 1 999 ? 61.055 48.256 -15.868 1.00 13.46 ? 999 VAL A C 1 ATOM 8068 O O . VAL A 1 999 ? 61.822 49.170 -15.540 1.00 13.93 ? 999 VAL A O 1 ATOM 8069 C CB . VAL A 1 999 ? 58.722 49.137 -15.667 1.00 12.70 ? 999 VAL A CB 1 ATOM 8070 C CG1 . VAL A 1 999 ? 57.617 49.732 -16.513 1.00 14.31 ? 999 VAL A CG1 1 ATOM 8071 C CG2 . VAL A 1 999 ? 58.150 48.070 -14.744 1.00 15.38 ? 999 VAL A CG2 1 ATOM 8072 N N . CYS A 1 1000 ? 61.305 46.966 -15.580 1.00 13.27 ? 1000 CYS A N 1 ATOM 8073 C CA . CYS A 1 1000 ? 62.468 46.641 -14.806 1.00 14.97 ? 1000 CYS A CA 1 ATOM 8074 C C . CYS A 1 1000 ? 63.796 46.847 -15.546 1.00 14.84 ? 1000 CYS A C 1 ATOM 8075 O O . CYS A 1 1000 ? 64.837 46.921 -14.897 1.00 16.92 ? 1000 CYS A O 1 ATOM 8076 C CB . CYS A 1 1000 ? 62.326 45.228 -14.267 1.00 15.61 ? 1000 CYS A CB 1 ATOM 8077 S SG . CYS A 1 1000 ? 61.427 45.269 -12.636 1.00 20.69 ? 1000 CYS A SG 1 ATOM 8078 N N . HIS A 1 1001 ? 63.723 47.015 -16.878 1.00 15.37 ? 1001 HIS A N 1 ATOM 8079 C CA . HIS A 1 1001 ? 64.928 47.269 -17.668 1.00 15.40 ? 1001 HIS A CA 1 ATOM 8080 C C . HIS A 1 1001 ? 65.022 48.705 -18.201 1.00 17.69 ? 1001 HIS A C 1 ATOM 8081 O O . HIS A 1 1001 ? 65.836 49.006 -19.060 1.00 19.55 ? 1001 HIS A O 1 ATOM 8082 C CB . HIS A 1 1001 ? 65.059 46.231 -18.786 1.00 18.10 ? 1001 HIS A CB 1 ATOM 8083 C CG . HIS A 1 1001 ? 65.648 44.924 -18.334 1.00 17.81 ? 1001 HIS A CG 1 ATOM 8084 N ND1 . HIS A 1 1001 ? 64.877 43.891 -17.854 1.00 19.32 ? 1001 HIS A ND1 1 ATOM 8085 C CD2 . HIS A 1 1001 ? 66.937 44.517 -18.213 1.00 22.27 ? 1001 HIS A CD2 1 ATOM 8086 C CE1 . HIS A 1 1001 ? 65.657 42.899 -17.448 1.00 18.90 ? 1001 HIS A CE1 1 ATOM 8087 N NE2 . HIS A 1 1001 ? 66.917 43.251 -17.656 1.00 20.21 ? 1001 HIS A NE2 1 ATOM 8088 N N . LEU A 1 1002 ? 64.199 49.622 -17.690 1.00 15.29 ? 1002 LEU A N 1 ATOM 8089 C CA . LEU A 1 1002 ? 64.286 51.017 -18.127 1.00 13.20 ? 1002 LEU A CA 1 ATOM 8090 C C . LEU A 1 1002 ? 65.546 51.668 -17.583 1.00 16.54 ? 1002 LEU A C 1 ATOM 8091 O O . LEU A 1 1002 ? 66.053 52.614 -18.202 1.00 19.72 ? 1002 LEU A O 1 ATOM 8092 C CB . LEU A 1 1002 ? 63.077 51.847 -17.642 1.00 15.94 ? 1002 LEU A CB 1 ATOM 8093 C CG . LEU A 1 1002 ? 61.826 51.608 -18.440 1.00 14.16 ? 1002 LEU A CG 1 ATOM 8094 C CD1 . LEU A 1 1002 ? 60.659 52.300 -17.752 1.00 14.59 ? 1002 LEU A CD1 1 ATOM 8095 C CD2 . LEU A 1 1002 ? 61.982 52.178 -19.864 1.00 18.45 ? 1002 LEU A CD2 1 ATOM 8096 N N . LEU A 1 1003 ? 66.038 51.250 -16.424 1.00 16.91 ? 1003 LEU A N 1 ATOM 8097 C CA . LEU A 1 1003 ? 67.277 51.787 -15.855 1.00 17.20 ? 1003 LEU A CA 1 ATOM 8098 C C . LEU A 1 1003 ? 68.308 50.665 -15.992 1.00 18.61 ? 1003 LEU A C 1 ATOM 8099 O O . LEU A 1 1003 ? 67.987 49.479 -15.872 1.00 18.56 ? 1003 LEU A O 1 ATOM 8100 C CB . LEU A 1 1003 ? 67.102 52.198 -14.389 1.00 16.48 ? 1003 LEU A CB 1 ATOM 8101 C CG . LEU A 1 1003 ? 66.415 53.573 -14.326 1.00 23.47 ? 1003 LEU A CG 1 ATOM 8102 C CD1 . LEU A 1 1003 ? 65.780 53.721 -12.959 1.00 25.87 ? 1003 LEU A CD1 1 ATOM 8103 C CD2 . LEU A 1 1003 ? 67.427 54.712 -14.623 1.00 24.19 ? 1003 LEU A CD2 1 ATOM 8104 N N . PRO A 1 1004 ? 69.562 51.041 -16.195 1.00 19.11 ? 1004 PRO A N 1 ATOM 8105 C CA . PRO A 1 1004 ? 70.576 50.001 -16.363 1.00 16.72 ? 1004 PRO A CA 1 ATOM 8106 C C . PRO A 1 1004 ? 71.009 49.315 -15.097 1.00 17.45 ? 1004 PRO A C 1 ATOM 8107 O O . PRO A 1 1004 ? 70.638 49.687 -13.950 1.00 17.04 ? 1004 PRO A O 1 ATOM 8108 C CB . PRO A 1 1004 ? 71.732 50.763 -17.025 1.00 19.96 ? 1004 PRO A CB 1 ATOM 8109 C CG . PRO A 1 1004 ? 71.645 52.112 -16.373 1.00 20.97 ? 1004 PRO A CG 1 ATOM 8110 C CD . PRO A 1 1004 ? 70.131 52.392 -16.311 1.00 20.41 ? 1004 PRO A CD 1 ATOM 8111 N N . ASN A 1 1005 ? 71.800 48.262 -15.316 1.00 18.91 ? 1005 ASN A N 1 ATOM 8112 C CA . ASN A 1 1005 ? 72.383 47.500 -14.206 1.00 19.33 ? 1005 ASN A CA 1 ATOM 8113 C C . ASN A 1 1005 ? 71.331 46.905 -13.252 1.00 18.64 ? 1005 ASN A C 1 ATOM 8114 O O . ASN A 1 1005 ? 71.514 46.943 -12.048 1.00 18.48 ? 1005 ASN A O 1 ATOM 8115 C CB . ASN A 1 1005 ? 73.333 48.385 -13.399 1.00 22.31 ? 1005 ASN A CB 1 ATOM 8116 C CG . ASN A 1 1005 ? 74.324 49.139 -14.286 1.00 27.47 ? 1005 ASN A CG 1 ATOM 8117 O OD1 . ASN A 1 1005 ? 74.377 50.397 -14.286 1.00 32.20 ? 1005 ASN A OD1 1 ATOM 8118 N ND2 . ASN A 1 1005 ? 75.089 48.391 -15.052 1.00 26.30 ? 1005 ASN A ND2 1 ATOM 8119 N N . VAL A 1 1006 ? 70.281 46.324 -13.803 1.00 17.90 ? 1006 VAL A N 1 ATOM 8120 C CA . VAL A 1 1006 ? 69.233 45.744 -12.966 1.00 18.61 ? 1006 VAL A CA 1 ATOM 8121 C C . VAL A 1 1006 ? 69.783 44.448 -12.304 1.00 19.05 ? 1006 VAL A C 1 ATOM 8122 O O . VAL A 1 1006 ? 70.357 43.611 -12.975 1.00 23.30 ? 1006 VAL A O 1 ATOM 8123 C CB . VAL A 1 1006 ? 67.884 45.498 -13.782 1.00 17.65 ? 1006 VAL A CB 1 ATOM 8124 C CG1 . VAL A 1 1006 ? 67.985 44.442 -14.791 1.00 20.94 ? 1006 VAL A CG1 1 ATOM 8125 C CG2 . VAL A 1 1006 ? 66.780 45.083 -12.823 1.00 16.57 ? 1006 VAL A CG2 1 ATOM 8126 N N . ALA A 1 1007 ? 69.561 44.319 -11.005 1.00 16.91 ? 1007 ALA A N 1 ATOM 8127 C CA . ALA A 1 1007 ? 70.010 43.183 -10.183 1.00 18.32 ? 1007 ALA A CA 1 ATOM 8128 C C . ALA A 1 1007 ? 68.811 42.336 -9.737 1.00 20.87 ? 1007 ALA A C 1 ATOM 8129 O O . ALA A 1 1007 ? 68.954 41.130 -9.453 1.00 21.76 ? 1007 ALA A O 1 ATOM 8130 C CB . ALA A 1 1007 ? 70.787 43.724 -8.939 1.00 19.71 ? 1007 ALA A CB 1 ATOM 8131 N N . ARG A 1 1008 ? 67.606 42.936 -9.665 1.00 18.71 ? 1008 ARG A N 1 ATOM 8132 C CA . ARG A 1 1008 ? 66.427 42.187 -9.206 1.00 16.26 ? 1008 ARG A CA 1 ATOM 8133 C C . ARG A 1 1008 ? 65.176 42.939 -9.660 1.00 14.31 ? 1008 ARG A C 1 ATOM 8134 O O . ARG A 1 1008 ? 65.223 44.191 -9.785 1.00 16.10 ? 1008 ARG A O 1 ATOM 8135 C CB . ARG A 1 1008 ? 66.441 42.153 -7.683 1.00 17.03 ? 1008 ARG A CB 1 ATOM 8136 C CG . ARG A 1 1008 ? 65.442 41.212 -7.044 1.00 22.40 ? 1008 ARG A CG 1 ATOM 8137 C CD . ARG A 1 1008 ? 65.512 41.370 -5.501 1.00 23.97 ? 1008 ARG A CD 1 ATOM 8138 N NE . ARG A 1 1008 ? 64.755 40.328 -4.786 1.00 35.00 ? 1008 ARG A NE 1 ATOM 8139 C CZ . ARG A 1 1008 ? 65.114 39.034 -4.709 1.00 38.49 ? 1008 ARG A CZ 1 ATOM 8140 N NH1 . ARG A 1 1008 ? 66.237 38.583 -5.291 1.00 40.34 ? 1008 ARG A NH1 1 ATOM 8141 N NH2 . ARG A 1 1008 ? 64.331 38.172 -4.062 1.00 35.87 ? 1008 ARG A NH2 1 ATOM 8142 N N . CYS A 1 1009 ? 64.105 42.192 -9.890 1.00 14.72 ? 1009 CYS A N 1 ATOM 8143 C CA . CYS A 1 1009 ? 62.800 42.819 -10.262 1.00 15.15 ? 1009 CYS A CA 1 ATOM 8144 C C . CYS A 1 1009 ? 61.772 42.101 -9.399 1.00 15.30 ? 1009 CYS A C 1 ATOM 8145 O O . CYS A 1 1009 ? 61.706 40.842 -9.389 1.00 14.99 ? 1009 CYS A O 1 ATOM 8146 C CB . CYS A 1 1009 ? 62.499 42.600 -11.720 1.00 15.00 ? 1009 CYS A CB 1 ATOM 8147 S SG . CYS A 1 1009 ? 60.938 43.331 -12.385 1.00 19.67 ? 1009 CYS A SG 1 ATOM 8148 N N A GLU A 1 1010 ? 60.948 42.865 -8.681 0.50 12.86 ? 1010 GLU A N 1 ATOM 8149 N N B GLU A 1 1010 ? 60.948 42.865 -8.681 0.50 13.87 ? 1010 GLU A N 1 ATOM 8150 C CA A GLU A 1 1010 ? 59.941 42.279 -7.824 0.50 12.00 ? 1010 GLU A CA 1 ATOM 8151 C CA B GLU A 1 1010 ? 59.941 42.279 -7.824 0.50 13.60 ? 1010 GLU A CA 1 ATOM 8152 C C A GLU A 1 1010 ? 58.559 42.870 -8.092 0.50 11.77 ? 1010 GLU A C 1 ATOM 8153 C C B GLU A 1 1010 ? 58.559 42.870 -8.092 0.50 12.96 ? 1010 GLU A C 1 ATOM 8154 O O A GLU A 1 1010 ? 58.426 44.069 -8.376 0.50 13.10 ? 1010 GLU A O 1 ATOM 8155 O O B GLU A 1 1010 ? 58.426 44.069 -8.376 0.50 13.85 ? 1010 GLU A O 1 ATOM 8156 C CB A GLU A 1 1010 ? 60.275 42.554 -6.348 0.50 14.59 ? 1010 GLU A CB 1 ATOM 8157 C CB B GLU A 1 1010 ? 60.275 42.554 -6.348 0.50 17.72 ? 1010 GLU A CB 1 ATOM 8158 C CG A GLU A 1 1010 ? 61.535 41.755 -5.874 0.50 17.70 ? 1010 GLU A CG 1 ATOM 8159 C CG B GLU A 1 1010 ? 61.517 41.733 -5.866 0.50 24.16 ? 1010 GLU A CG 1 ATOM 8160 C CD A GLU A 1 1010 ? 62.350 42.362 -4.720 0.50 19.98 ? 1010 GLU A CD 1 ATOM 8161 C CD B GLU A 1 1010 ? 61.237 40.482 -5.016 0.50 27.20 ? 1010 GLU A CD 1 ATOM 8162 O OE1 A GLU A 1 1010 ? 62.791 43.534 -4.780 0.50 19.15 ? 1010 GLU A OE1 1 ATOM 8163 O OE1 B GLU A 1 1010 ? 60.103 40.266 -4.530 0.50 31.86 ? 1010 GLU A OE1 1 ATOM 8164 O OE2 A GLU A 1 1010 ? 62.596 41.613 -3.735 0.50 23.65 ? 1010 GLU A OE2 1 ATOM 8165 O OE2 B GLU A 1 1010 ? 62.211 39.711 -4.791 0.50 33.27 ? 1010 GLU A OE2 1 ATOM 8166 N N . ARG A 1 1011 ? 57.556 42.036 -8.064 1.00 11.35 ? 1011 ARG A N 1 ATOM 8167 C CA . ARG A 1 1011 ? 56.169 42.565 -8.084 1.00 9.70 ? 1011 ARG A CA 1 ATOM 8168 C C . ARG A 1 1011 ? 55.842 42.901 -6.615 1.00 11.48 ? 1011 ARG A C 1 ATOM 8169 O O . ARG A 1 1011 ? 56.153 42.111 -5.694 1.00 12.59 ? 1011 ARG A O 1 ATOM 8170 C CB . ARG A 1 1011 ? 55.172 41.542 -8.590 1.00 12.08 ? 1011 ARG A CB 1 ATOM 8171 C CG . ARG A 1 1011 ? 53.766 42.199 -8.813 1.00 15.22 ? 1011 ARG A CG 1 ATOM 8172 C CD . ARG A 1 1011 ? 52.866 41.329 -9.629 1.00 21.49 ? 1011 ARG A CD 1 ATOM 8173 N NE . ARG A 1 1011 ? 52.589 40.142 -8.845 1.00 23.41 ? 1011 ARG A NE 1 ATOM 8174 C CZ . ARG A 1 1011 ? 51.632 40.034 -7.915 1.00 28.39 ? 1011 ARG A CZ 1 ATOM 8175 N NH1 . ARG A 1 1011 ? 50.833 41.066 -7.639 1.00 32.01 ? 1011 ARG A NH1 1 ATOM 8176 N NH2 . ARG A 1 1011 ? 51.462 38.879 -7.264 1.00 28.42 ? 1011 ARG A NH2 1 ATOM 8177 N N . THR A 1 1012 ? 55.222 44.048 -6.355 1.00 9.68 ? 1012 THR A N 1 ATOM 8178 C CA . THR A 1 1012 ? 54.909 44.477 -5.006 1.00 8.92 ? 1012 THR A CA 1 ATOM 8179 C C . THR A 1 1012 ? 53.429 44.914 -4.930 1.00 9.94 ? 1012 THR A C 1 ATOM 8180 O O . THR A 1 1012 ? 52.733 45.068 -5.940 1.00 10.14 ? 1012 THR A O 1 ATOM 8181 C CB . THR A 1 1012 ? 55.758 45.731 -4.595 1.00 10.61 ? 1012 THR A CB 1 ATOM 8182 O OG1 . THR A 1 1012 ? 55.428 46.850 -5.452 1.00 10.85 ? 1012 THR A OG1 1 ATOM 8183 C CG2 . THR A 1 1012 ? 57.231 45.465 -4.779 1.00 11.51 ? 1012 THR A CG2 1 ATOM 8184 N N . THR A 1 1013 ? 52.991 45.150 -3.719 1.00 9.13 ? 1013 THR A N 1 ATOM 8185 C CA . THR A 1 1013 ? 51.699 45.788 -3.517 1.00 9.97 ? 1013 THR A CA 1 ATOM 8186 C C . THR A 1 1013 ? 51.829 47.194 -4.145 1.00 9.08 ? 1013 THR A C 1 ATOM 8187 O O . THR A 1 1013 ? 52.921 47.762 -4.378 1.00 8.68 ? 1013 THR A O 1 ATOM 8188 C CB . THR A 1 1013 ? 51.397 45.934 -2.045 1.00 9.26 ? 1013 THR A CB 1 ATOM 8189 O OG1 . THR A 1 1013 ? 52.578 46.393 -1.355 1.00 9.57 ? 1013 THR A OG1 1 ATOM 8190 C CG2 . THR A 1 1013 ? 50.919 44.551 -1.469 1.00 11.53 ? 1013 THR A CG2 1 ATOM 8191 N N . LEU A 1 1014 ? 50.670 47.852 -4.387 1.00 8.12 ? 1014 LEU A N 1 ATOM 8192 C CA . LEU A 1 1014 ? 50.684 49.170 -5.096 1.00 7.77 ? 1014 LEU A CA 1 ATOM 8193 C C . LEU A 1 1014 ? 51.341 50.292 -4.364 1.00 6.51 ? 1014 LEU A C 1 ATOM 8194 O O . LEU A 1 1014 ? 51.721 51.287 -4.981 1.00 8.25 ? 1014 LEU A O 1 ATOM 8195 C CB . LEU A 1 1014 ? 49.259 49.603 -5.508 1.00 7.77 ? 1014 LEU A CB 1 ATOM 8196 C CG . LEU A 1 1014 ? 48.520 48.621 -6.420 1.00 8.35 ? 1014 LEU A CG 1 ATOM 8197 C CD1 . LEU A 1 1014 ? 47.182 49.334 -6.824 1.00 9.61 ? 1014 LEU A CD1 1 ATOM 8198 C CD2 . LEU A 1 1014 ? 49.310 48.228 -7.661 1.00 10.08 ? 1014 LEU A CD2 1 ATOM 8199 N N . THR A 1 1015 ? 51.510 50.150 -3.057 1.00 7.69 ? 1015 THR A N 1 ATOM 8200 C CA . THR A 1 1015 ? 52.191 51.129 -2.212 1.00 8.36 ? 1015 THR A CA 1 ATOM 8201 C C . THR A 1 1015 ? 53.708 50.878 -2.167 1.00 7.34 ? 1015 THR A C 1 ATOM 8202 O O . THR A 1 1015 ? 54.414 51.660 -1.511 1.00 8.86 ? 1015 THR A O 1 ATOM 8203 C CB . THR A 1 1015 ? 51.675 51.027 -0.791 1.00 8.62 ? 1015 THR A CB 1 ATOM 8204 O OG1 . THR A 1 1015 ? 51.850 49.640 -0.425 1.00 8.73 ? 1015 THR A OG1 1 ATOM 8205 C CG2 . THR A 1 1015 ? 50.166 51.389 -0.672 1.00 9.99 ? 1015 THR A CG2 1 ATOM 8206 N N . PHE A 1 1016 ? 54.154 49.812 -2.836 1.00 8.57 ? 1016 PHE A N 1 ATOM 8207 C CA . PHE A 1 1016 ? 55.582 49.360 -2.878 1.00 8.75 ? 1016 PHE A CA 1 ATOM 8208 C C . PHE A 1 1016 ? 56.034 48.813 -1.546 1.00 10.22 ? 1016 PHE A C 1 ATOM 8209 O O . PHE A 1 1016 ? 57.228 48.503 -1.430 1.00 11.69 ? 1016 PHE A O 1 ATOM 8210 C CB . PHE A 1 1016 ? 56.543 50.487 -3.317 1.00 9.17 ? 1016 PHE A CB 1 ATOM 8211 C CG . PHE A 1 1016 ? 56.177 51.125 -4.626 1.00 7.97 ? 1016 PHE A CG 1 ATOM 8212 C CD1 . PHE A 1 1016 ? 55.973 52.522 -4.694 1.00 9.39 ? 1016 PHE A CD1 1 ATOM 8213 C CD2 . PHE A 1 1016 ? 56.069 50.361 -5.792 1.00 9.26 ? 1016 PHE A CD2 1 ATOM 8214 C CE1 . PHE A 1 1016 ? 55.680 53.104 -5.942 1.00 8.78 ? 1016 PHE A CE1 1 ATOM 8215 C CE2 . PHE A 1 1016 ? 55.769 50.995 -7.019 1.00 10.20 ? 1016 PHE A CE2 1 ATOM 8216 C CZ . PHE A 1 1016 ? 55.586 52.333 -7.080 1.00 10.03 ? 1016 PHE A CZ 1 ATOM 8217 N N . LEU A 1 1017 ? 55.129 48.584 -0.578 1.00 8.84 ? 1017 LEU A N 1 ATOM 8218 C CA . LEU A 1 1017 ? 55.582 48.203 0.780 1.00 10.57 ? 1017 LEU A CA 1 ATOM 8219 C C . LEU A 1 1017 ? 55.751 46.722 1.011 1.00 11.47 ? 1017 LEU A C 1 ATOM 8220 O O . LEU A 1 1017 ? 56.343 46.372 2.045 1.00 15.17 ? 1017 LEU A O 1 ATOM 8221 C CB . LEU A 1 1017 ? 54.616 48.829 1.806 1.00 9.99 ? 1017 LEU A CB 1 ATOM 8222 C CG . LEU A 1 1017 ? 54.631 50.364 1.749 1.00 9.47 ? 1017 LEU A CG 1 ATOM 8223 C CD1 . LEU A 1 1017 ? 53.599 50.882 2.715 1.00 10.92 ? 1017 LEU A CD1 1 ATOM 8224 C CD2 . LEU A 1 1017 ? 55.978 50.975 2.098 1.00 12.86 ? 1017 LEU A CD2 1 ATOM 8225 N N . GLN A 1 1018 ? 55.281 45.841 0.152 1.00 10.73 ? 1018 GLN A N 1 ATOM 8226 C CA . GLN A 1 1018 ? 55.462 44.403 0.391 1.00 11.64 ? 1018 GLN A CA 1 ATOM 8227 C C . GLN A 1 1018 ? 55.813 43.745 -0.929 1.00 12.67 ? 1018 GLN A C 1 ATOM 8228 O O . GLN A 1 1018 ? 55.160 44.012 -1.963 1.00 12.19 ? 1018 GLN A O 1 ATOM 8229 C CB . GLN A 1 1018 ? 54.172 43.779 0.952 1.00 12.71 ? 1018 GLN A CB 1 ATOM 8230 C CG . GLN A 1 1018 ? 54.417 42.264 1.268 1.00 17.26 ? 1018 GLN A CG 1 ATOM 8231 C CD . GLN A 1 1018 ? 53.176 41.454 1.547 1.00 26.81 ? 1018 GLN A CD 1 ATOM 8232 O OE1 . GLN A 1 1018 ? 53.249 40.202 1.695 1.00 28.04 ? 1018 GLN A OE1 1 ATOM 8233 N NE2 . GLN A 1 1018 ? 52.029 42.117 1.599 1.00 21.53 ? 1018 GLN A NE2 1 ATOM 8234 N N . ASN A 1 1019 ? 56.852 42.899 -0.923 1.00 12.72 ? 1019 ASN A N 1 ATOM 8235 C CA . ASN A 1 1019 ? 57.259 42.154 -2.109 1.00 13.47 ? 1019 ASN A CA 1 ATOM 8236 C C . ASN A 1 1019 ? 56.343 40.947 -2.244 1.00 15.65 ? 1019 ASN A C 1 ATOM 8237 O O . ASN A 1 1019 ? 56.167 40.171 -1.263 1.00 18.47 ? 1019 ASN A O 1 ATOM 8238 C CB . ASN A 1 1019 ? 58.715 41.699 -1.982 1.00 15.39 ? 1019 ASN A CB 1 ATOM 8239 C CG . ASN A 1 1019 ? 59.673 42.884 -1.899 1.00 17.99 ? 1019 ASN A CG 1 ATOM 8240 O OD1 . ASN A 1 1019 ? 59.422 43.966 -2.508 1.00 17.48 ? 1019 ASN A OD1 1 ATOM 8241 N ND2 . ASN A 1 1019 ? 60.795 42.726 -1.156 1.00 22.78 ? 1019 ASN A ND2 1 ATOM 8242 N N . LEU A 1 1020 ? 55.769 40.741 -3.412 1.00 14.75 ? 1020 LEU A N 1 ATOM 8243 C CA . LEU A 1 1020 ? 54.843 39.652 -3.661 1.00 16.85 ? 1020 LEU A CA 1 ATOM 8244 C C . LEU A 1 1020 ? 55.434 38.559 -4.538 1.00 16.51 ? 1020 LEU A C 1 ATOM 8245 O O . LEU A 1 1020 ? 54.991 37.391 -4.434 1.00 18.76 ? 1020 LEU A O 1 ATOM 8246 C CB . LEU A 1 1020 ? 53.553 40.167 -4.332 1.00 17.41 ? 1020 LEU A CB 1 ATOM 8247 C CG . LEU A 1 1020 ? 52.837 41.229 -3.482 1.00 15.43 ? 1020 LEU A CG 1 ATOM 8248 C CD1 . LEU A 1 1020 ? 51.675 41.768 -4.311 1.00 19.08 ? 1020 LEU A CD1 1 ATOM 8249 C CD2 . LEU A 1 1020 ? 52.289 40.655 -2.157 1.00 19.15 ? 1020 LEU A CD2 1 ATOM 8250 N N . GLU A 1 1021 ? 56.392 38.894 -5.383 1.00 15.61 ? 1021 GLU A N 1 ATOM 8251 C CA . GLU A 1 1021 ? 56.967 37.909 -6.315 1.00 18.66 ? 1021 GLU A CA 1 ATOM 8252 C C . GLU A 1 1021 ? 58.315 38.325 -6.799 1.00 18.66 ? 1021 GLU A C 1 ATOM 8253 O O . GLU A 1 1021 ? 58.537 39.476 -7.168 1.00 18.17 ? 1021 GLU A O 1 ATOM 8254 C CB . GLU A 1 1021 ? 56.027 37.723 -7.516 1.00 21.49 ? 1021 GLU A CB 1 ATOM 8255 C CG . GLU A 1 1021 ? 56.477 36.606 -8.472 1.00 28.47 ? 1021 GLU A CG 1 ATOM 8256 C CD . GLU A 1 1021 ? 55.575 36.452 -9.680 1.00 35.29 ? 1021 GLU A CD 1 ATOM 8257 O OE1 . GLU A 1 1021 ? 55.903 35.577 -10.524 1.00 38.86 ? 1021 GLU A OE1 1 ATOM 8258 O OE2 . GLU A 1 1021 ? 54.573 37.204 -9.784 1.00 33.44 ? 1021 GLU A OE2 1 ATOM 8259 N N . HIS A 1 1022 ? 59.254 37.381 -6.835 1.00 20.48 ? 1022 HIS A N 1 ATOM 8260 C CA . HIS A 1 1022 ? 60.598 37.636 -7.314 1.00 20.10 ? 1022 HIS A CA 1 ATOM 8261 C C . HIS A 1 1022 ? 60.498 37.217 -8.774 1.00 21.89 ? 1022 HIS A C 1 ATOM 8262 O O . HIS A 1 1022 ? 60.123 36.076 -9.093 1.00 23.51 ? 1022 HIS A O 1 ATOM 8263 C CB . HIS A 1 1022 ? 61.558 36.752 -6.521 1.00 22.96 ? 1022 HIS A CB 1 ATOM 8264 C CG . HIS A 1 1022 ? 62.983 36.944 -6.901 1.00 30.11 ? 1022 HIS A CG 1 ATOM 8265 N ND1 . HIS A 1 1022 ? 63.936 35.972 -6.687 1.00 33.98 ? 1022 HIS A ND1 1 ATOM 8266 C CD2 . HIS A 1 1022 ? 63.620 37.970 -7.523 1.00 32.75 ? 1022 HIS A CD2 1 ATOM 8267 C CE1 . HIS A 1 1022 ? 65.096 36.381 -7.178 1.00 36.05 ? 1022 HIS A CE1 1 ATOM 8268 N NE2 . HIS A 1 1022 ? 64.932 37.589 -7.692 1.00 36.36 ? 1022 HIS A NE2 1 ATOM 8269 N N . LEU A 1 1023 ? 60.829 38.119 -9.684 1.00 16.72 ? 1023 LEU A N 1 ATOM 8270 C CA . LEU A 1 1023 ? 60.579 37.860 -11.075 1.00 20.31 ? 1023 LEU A CA 1 ATOM 8271 C C . LEU A 1 1023 ? 61.721 37.294 -11.884 1.00 18.81 ? 1023 LEU A C 1 ATOM 8272 O O . LEU A 1 1023 ? 62.814 37.870 -11.919 1.00 20.01 ? 1023 LEU A O 1 ATOM 8273 C CB . LEU A 1 1023 ? 60.090 39.158 -11.725 1.00 19.59 ? 1023 LEU A CB 1 ATOM 8274 C CG . LEU A 1 1023 ? 58.752 39.637 -11.150 1.00 19.25 ? 1023 LEU A CG 1 ATOM 8275 C CD1 . LEU A 1 1023 ? 58.519 41.099 -11.449 1.00 19.98 ? 1023 LEU A CD1 1 ATOM 8276 C CD2 . LEU A 1 1023 ? 57.634 38.761 -11.745 1.00 22.43 ? 1023 LEU A CD2 1 ATOM 8277 N N . ASP A 1 1024 ? 61.428 36.222 -12.604 1.00 26.00 ? 1024 ASP A N 1 ATOM 8278 C CA . ASP A 1 1024 ? 62.475 35.617 -13.396 1.00 27.47 ? 1024 ASP A CA 1 ATOM 8279 C C . ASP A 1 1024 ? 62.958 36.449 -14.534 1.00 26.47 ? 1024 ASP A C 1 ATOM 8280 O O . ASP A 1 1024 ? 62.185 37.144 -15.229 1.00 26.46 ? 1024 ASP A O 1 ATOM 8281 C CB . ASP A 1 1024 ? 62.048 34.232 -13.853 1.00 34.70 ? 1024 ASP A CB 1 ATOM 8282 C CG . ASP A 1 1024 ? 62.508 33.175 -12.868 1.00 42.59 ? 1024 ASP A CG 1 ATOM 8283 O OD1 . ASP A 1 1024 ? 62.147 33.308 -11.667 1.00 45.55 ? 1024 ASP A OD1 1 ATOM 8284 O OD2 . ASP A 1 1024 ? 63.253 32.242 -13.280 1.00 48.48 ? 1024 ASP A OD2 1 ATOM 8285 N N . GLY A 1 1025 ? 64.269 36.395 -14.684 1.00 23.24 ? 1025 GLY A N 1 ATOM 8286 C CA . GLY A 1 1025 ? 64.953 37.111 -15.732 1.00 23.08 ? 1025 GLY A CA 1 ATOM 8287 C C . GLY A 1 1025 ? 64.942 38.594 -15.459 1.00 21.76 ? 1025 GLY A C 1 ATOM 8288 O O . GLY A 1 1025 ? 65.389 39.351 -16.299 1.00 23.22 ? 1025 GLY A O 1 ATOM 8289 N N A MET A 1 1026 ? 64.486 38.998 -14.264 0.50 20.18 ? 1026 MET A N 1 ATOM 8290 N N B MET A 1 1026 ? 64.486 38.998 -14.264 0.50 21.00 ? 1026 MET A N 1 ATOM 8291 C CA A MET A 1 1026 ? 64.396 40.420 -13.907 0.50 20.67 ? 1026 MET A CA 1 ATOM 8292 C CA B MET A 1 1026 ? 64.396 40.420 -13.907 0.50 21.88 ? 1026 MET A CA 1 ATOM 8293 C C A MET A 1 1026 ? 63.444 41.136 -14.855 0.50 18.88 ? 1026 MET A C 1 ATOM 8294 C C B MET A 1 1026 ? 63.444 41.136 -14.855 0.50 19.66 ? 1026 MET A C 1 ATOM 8295 O O A MET A 1 1026 ? 63.622 42.335 -15.100 0.50 21.34 ? 1026 MET A O 1 ATOM 8296 O O B MET A 1 1026 ? 63.622 42.335 -15.100 0.50 21.91 ? 1026 MET A O 1 ATOM 8297 C CB A MET A 1 1026 ? 65.773 41.080 -13.945 0.50 20.48 ? 1026 MET A CB 1 ATOM 8298 C CB B MET A 1 1026 ? 65.773 41.080 -13.945 0.50 23.28 ? 1026 MET A CB 1 ATOM 8299 C CG A MET A 1 1026 ? 66.676 40.438 -12.901 0.50 23.24 ? 1026 MET A CG 1 ATOM 8300 C CG B MET A 1 1026 ? 66.676 40.438 -12.901 0.50 27.58 ? 1026 MET A CG 1 ATOM 8301 S SD A MET A 1 1026 ? 68.380 40.998 -12.915 0.50 23.23 ? 1026 MET A SD 1 ATOM 8302 S SD B MET A 1 1026 ? 67.962 39.371 -13.554 0.50 32.55 ? 1026 MET A SD 1 ATOM 8303 C CE A MET A 1 1026 ? 68.881 40.525 -14.640 0.50 25.58 ? 1026 MET A CE 1 ATOM 8304 C CE B MET A 1 1026 ? 69.090 40.628 -14.326 0.50 31.87 ? 1026 MET A CE 1 ATOM 8305 N N . VAL A 1 1027 ? 62.440 40.425 -15.349 1.00 18.25 ? 1027 VAL A N 1 ATOM 8306 C CA . VAL A 1 1027 ? 61.493 40.986 -16.296 1.00 20.18 ? 1027 VAL A CA 1 ATOM 8307 C C . VAL A 1 1027 ? 60.148 41.202 -15.662 1.00 19.75 ? 1027 VAL A C 1 ATOM 8308 O O . VAL A 1 1027 ? 59.566 40.299 -15.057 1.00 21.19 ? 1027 VAL A O 1 ATOM 8309 C CB . VAL A 1 1027 ? 61.307 40.074 -17.521 1.00 16.80 ? 1027 VAL A CB 1 ATOM 8310 C CG1 . VAL A 1 1027 ? 60.190 40.625 -18.423 1.00 19.83 ? 1027 VAL A CG1 1 ATOM 8311 C CG2 . VAL A 1 1027 ? 62.600 40.046 -18.331 1.00 21.27 ? 1027 VAL A CG2 1 ATOM 8312 N N . ALA A 1 1028 ? 59.616 42.408 -15.848 1.00 18.84 ? 1028 ALA A N 1 ATOM 8313 C CA . ALA A 1 1028 ? 58.287 42.753 -15.276 1.00 20.52 ? 1028 ALA A CA 1 ATOM 8314 C C . ALA A 1 1028 ? 57.299 42.578 -16.354 1.00 21.25 ? 1028 ALA A C 1 ATOM 8315 O O . ALA A 1 1028 ? 57.317 43.337 -17.350 1.00 22.02 ? 1028 ALA A O 1 ATOM 8316 C CB . ALA A 1 1028 ? 58.256 44.219 -14.804 1.00 19.03 ? 1028 ALA A CB 1 ATOM 8317 N N . PRO A 1 1029 ? 56.400 41.611 -16.200 1.00 18.20 ? 1029 PRO A N 1 ATOM 8318 C CA . PRO A 1 1029 ? 55.378 41.368 -17.232 1.00 20.64 ? 1029 PRO A CA 1 ATOM 8319 C C . PRO A 1 1029 ? 54.385 42.526 -17.352 1.00 19.43 ? 1029 PRO A C 1 ATOM 8320 O O . PRO A 1 1029 ? 54.189 43.293 -16.416 1.00 24.46 ? 1029 PRO A O 1 ATOM 8321 C CB . PRO A 1 1029 ? 54.637 40.134 -16.723 1.00 20.61 ? 1029 PRO A CB 1 ATOM 8322 C CG . PRO A 1 1029 ? 55.535 39.535 -15.650 1.00 23.83 ? 1029 PRO A CG 1 ATOM 8323 C CD . PRO A 1 1029 ? 56.273 40.696 -15.051 1.00 18.80 ? 1029 PRO A CD 1 ATOM 8324 N N . GLU A 1 1030 ? 53.760 42.649 -18.497 1.00 19.73 ? 1030 GLU A N 1 ATOM 8325 C CA . GLU A 1 1030 ? 52.730 43.666 -18.638 1.00 20.34 ? 1030 GLU A CA 1 ATOM 8326 C C . GLU A 1 1030 ? 51.461 43.089 -17.975 1.00 21.31 ? 1030 GLU A C 1 ATOM 8327 O O . GLU A 1 1030 ? 51.293 41.846 -17.754 1.00 24.66 ? 1030 GLU A O 1 ATOM 8328 C CB . GLU A 1 1030 ? 52.478 43.984 -20.122 1.00 21.58 ? 1030 GLU A CB 1 ATOM 8329 C CG . GLU A 1 1030 ? 53.695 44.579 -20.885 1.00 20.04 ? 1030 GLU A CG 1 ATOM 8330 C CD . GLU A 1 1030 ? 53.310 44.953 -22.317 1.00 21.81 ? 1030 GLU A CD 1 ATOM 8331 O OE1 . GLU A 1 1030 ? 52.285 44.399 -22.812 1.00 25.71 ? 1030 GLU A OE1 1 ATOM 8332 O OE2 . GLU A 1 1030 ? 54.055 45.779 -22.927 1.00 19.46 ? 1030 GLU A OE2 1 ATOM 8333 N N . VAL A 1 1031 ? 50.541 43.971 -17.677 1.00 18.29 ? 1031 VAL A N 1 ATOM 8334 C CA . VAL A 1 1031 ? 49.346 43.554 -16.969 1.00 15.62 ? 1031 VAL A CA 1 ATOM 8335 C C . VAL A 1 1031 ? 48.175 43.361 -17.891 1.00 14.97 ? 1031 VAL A C 1 ATOM 8336 O O . VAL A 1 1031 ? 48.208 43.828 -19.026 1.00 17.00 ? 1031 VAL A O 1 ATOM 8337 C CB . VAL A 1 1031 ? 48.986 44.595 -15.866 1.00 18.81 ? 1031 VAL A CB 1 ATOM 8338 C CG1 . VAL A 1 1031 ? 50.166 44.673 -14.887 1.00 22.51 ? 1031 VAL A CG1 1 ATOM 8339 C CG2 . VAL A 1 1031 ? 48.653 45.942 -16.438 1.00 18.27 ? 1031 VAL A CG2 1 ATOM 8340 N N . CYS A 1 1032 ? 47.147 42.676 -17.415 1.00 13.30 ? 1032 CYS A N 1 ATOM 8341 C CA . CYS A 1 1032 ? 45.909 42.417 -18.167 1.00 14.28 ? 1032 CYS A CA 1 ATOM 8342 C C . CYS A 1 1032 ? 44.975 43.639 -18.210 1.00 13.01 ? 1032 CYS A C 1 ATOM 8343 O O . CYS A 1 1032 ? 45.079 44.542 -17.401 1.00 11.05 ? 1032 CYS A O 1 ATOM 8344 C CB . CYS A 1 1032 ? 45.110 41.314 -17.462 1.00 13.78 ? 1032 CYS A CB 1 ATOM 8345 S SG . CYS A 1 1032 ? 45.943 39.688 -17.624 1.00 23.13 ? 1032 CYS A SG 1 ATOM 8346 N N . PRO A 1 1033 ? 44.029 43.677 -19.164 1.00 11.39 ? 1033 PRO A N 1 ATOM 8347 C CA . PRO A 1 1033 ? 43.063 44.797 -19.236 1.00 10.59 ? 1033 PRO A CA 1 ATOM 8348 C C . PRO A 1 1033 ? 42.343 44.934 -17.880 1.00 10.04 ? 1033 PRO A C 1 ATOM 8349 O O . PRO A 1 1033 ? 41.825 43.975 -17.288 1.00 10.45 ? 1033 PRO A O 1 ATOM 8350 C CB . PRO A 1 1033 ? 42.060 44.385 -20.358 1.00 11.60 ? 1033 PRO A CB 1 ATOM 8351 C CG . PRO A 1 1033 ? 42.953 43.496 -21.245 1.00 13.46 ? 1033 PRO A CG 1 ATOM 8352 C CD . PRO A 1 1033 ? 43.784 42.680 -20.241 1.00 13.48 ? 1033 PRO A CD 1 ATOM 8353 N N . MET A 1 1034 ? 42.235 46.197 -17.468 1.00 9.50 ? 1034 MET A N 1 ATOM 8354 C CA . MET A 1 1034 ? 41.628 46.667 -16.217 1.00 10.66 ? 1034 MET A CA 1 ATOM 8355 C C . MET A 1 1034 ? 42.432 46.314 -14.969 1.00 11.86 ? 1034 MET A C 1 ATOM 8356 O O . MET A 1 1034 ? 41.969 46.630 -13.870 1.00 16.49 ? 1034 MET A O 1 ATOM 8357 C CB . MET A 1 1034 ? 40.133 46.200 -16.065 1.00 9.35 ? 1034 MET A CB 1 ATOM 8358 C CG . MET A 1 1034 ? 39.269 46.750 -17.203 1.00 11.07 ? 1034 MET A CG 1 ATOM 8359 S SD . MET A 1 1034 ? 39.310 48.538 -17.431 1.00 13.10 ? 1034 MET A SD 1 ATOM 8360 C CE . MET A 1 1034 ? 38.429 49.127 -15.895 1.00 14.65 ? 1034 MET A CE 1 ATOM 8361 N N . GLU A 1 1035 ? 43.623 45.802 -15.134 1.00 9.62 ? 1035 GLU A N 1 ATOM 8362 C CA . GLU A 1 1035 ? 44.466 45.474 -13.972 1.00 10.39 ? 1035 GLU A CA 1 ATOM 8363 C C . GLU A 1 1035 ? 45.544 46.545 -13.791 1.00 9.79 ? 1035 GLU A C 1 ATOM 8364 O O . GLU A 1 1035 ? 45.880 47.299 -14.709 1.00 10.45 ? 1035 GLU A O 1 ATOM 8365 C CB . GLU A 1 1035 ? 45.071 44.083 -14.155 1.00 15.06 ? 1035 GLU A CB 1 ATOM 8366 C CG . GLU A 1 1035 ? 43.963 42.948 -14.059 1.00 22.96 ? 1035 GLU A CG 1 ATOM 8367 C CD . GLU A 1 1035 ? 43.307 42.758 -12.655 1.00 29.17 ? 1035 GLU A CD 1 ATOM 8368 O OE1 . GLU A 1 1035 ? 43.311 43.674 -11.819 1.00 32.84 ? 1035 GLU A OE1 1 ATOM 8369 O OE2 . GLU A 1 1035 ? 42.742 41.675 -12.394 1.00 34.52 ? 1035 GLU A OE2 1 ATOM 8370 N N . THR A 1 1036 ? 46.029 46.612 -12.555 1.00 9.13 ? 1036 THR A N 1 ATOM 8371 C CA . THR A 1 1036 ? 47.076 47.543 -12.154 1.00 10.24 ? 1036 THR A CA 1 ATOM 8372 C C . THR A 1 1036 ? 48.064 46.724 -11.339 1.00 10.06 ? 1036 THR A C 1 ATOM 8373 O O . THR A 1 1036 ? 47.624 45.944 -10.450 1.00 11.37 ? 1036 THR A O 1 ATOM 8374 C CB . THR A 1 1036 ? 46.482 48.665 -11.278 1.00 10.63 ? 1036 THR A CB 1 ATOM 8375 O OG1 . THR A 1 1036 ? 45.417 49.281 -12.000 1.00 11.31 ? 1036 THR A OG1 1 ATOM 8376 C CG2 . THR A 1 1036 ? 47.520 49.721 -10.923 1.00 10.97 ? 1036 THR A CG2 1 ATOM 8377 N N . ALA A 1 1037 ? 49.370 46.832 -11.606 1.00 9.12 ? 1037 ALA A N 1 ATOM 8378 C CA . ALA A 1 1037 ? 50.385 46.109 -10.849 1.00 10.39 ? 1037 ALA A CA 1 ATOM 8379 C C . ALA A 1 1037 ? 51.513 47.046 -10.531 1.00 8.54 ? 1037 ALA A C 1 ATOM 8380 O O . ALA A 1 1037 ? 51.634 48.115 -11.156 1.00 11.28 ? 1037 ALA A O 1 ATOM 8381 C CB . ALA A 1 1037 ? 50.935 44.919 -11.693 1.00 13.28 ? 1037 ALA A CB 1 ATOM 8382 N N . ALA A 1 1038 ? 52.305 46.709 -9.531 1.00 8.87 ? 1038 ALA A N 1 ATOM 8383 C CA . ALA A 1 1038 ? 53.447 47.513 -9.175 1.00 9.40 ? 1038 ALA A CA 1 ATOM 8384 C C . ALA A 1 1038 ? 54.667 46.637 -9.210 1.00 9.09 ? 1038 ALA A C 1 ATOM 8385 O O . ALA A 1 1038 ? 54.610 45.443 -8.857 1.00 9.91 ? 1038 ALA A O 1 ATOM 8386 C CB . ALA A 1 1038 ? 53.268 48.133 -7.805 1.00 10.23 ? 1038 ALA A CB 1 ATOM 8387 N N . TYR A 1 1039 ? 55.751 47.270 -9.640 1.00 9.98 ? 1039 TYR A N 1 ATOM 8388 C CA . TYR A 1 1039 ? 57.026 46.562 -9.716 1.00 10.52 ? 1039 TYR A CA 1 ATOM 8389 C C . TYR A 1 1039 ? 58.115 47.431 -9.161 1.00 11.34 ? 1039 TYR A C 1 ATOM 8390 O O . TYR A 1 1039 ? 58.055 48.666 -9.297 1.00 11.98 ? 1039 TYR A O 1 ATOM 8391 C CB . TYR A 1 1039 ? 57.381 46.225 -11.166 1.00 10.75 ? 1039 TYR A CB 1 ATOM 8392 C CG . TYR A 1 1039 ? 56.407 45.347 -11.879 1.00 10.52 ? 1039 TYR A CG 1 ATOM 8393 C CD1 . TYR A 1 1039 ? 55.475 45.880 -12.779 1.00 12.81 ? 1039 TYR A CD1 1 ATOM 8394 C CD2 . TYR A 1 1039 ? 56.392 43.961 -11.625 1.00 12.29 ? 1039 TYR A CD2 1 ATOM 8395 C CE1 . TYR A 1 1039 ? 54.541 45.033 -13.437 1.00 16.09 ? 1039 TYR A CE1 1 ATOM 8396 C CE2 . TYR A 1 1039 ? 55.468 43.147 -12.239 1.00 14.34 ? 1039 TYR A CE2 1 ATOM 8397 C CZ . TYR A 1 1039 ? 54.559 43.704 -13.144 1.00 16.24 ? 1039 TYR A CZ 1 ATOM 8398 O OH . TYR A 1 1039 ? 53.710 42.900 -13.858 1.00 19.49 ? 1039 TYR A OH 1 ATOM 8399 N N . VAL A 1 1040 ? 59.129 46.813 -8.548 1.00 11.34 ? 1040 VAL A N 1 ATOM 8400 C CA . VAL A 1 1040 ? 60.280 47.567 -8.071 1.00 11.49 ? 1040 VAL A CA 1 ATOM 8401 C C . VAL A 1 1040 ? 61.538 46.928 -8.677 1.00 12.77 ? 1040 VAL A C 1 ATOM 8402 O O . VAL A 1 1040 ? 61.754 45.686 -8.533 1.00 13.65 ? 1040 VAL A O 1 ATOM 8403 C CB . VAL A 1 1040 ? 60.399 47.545 -6.537 1.00 12.08 ? 1040 VAL A CB 1 ATOM 8404 C CG1 . VAL A 1 1040 ? 61.774 48.224 -6.088 1.00 11.88 ? 1040 VAL A CG1 1 ATOM 8405 C CG2 . VAL A 1 1040 ? 59.202 48.294 -5.948 1.00 12.34 ? 1040 VAL A CG2 1 ATOM 8406 N N . SER A 1 1041 ? 62.348 47.732 -9.382 1.00 10.73 ? 1041 SER A N 1 ATOM 8407 C CA . SER A 1 1041 ? 63.617 47.233 -9.907 1.00 12.27 ? 1041 SER A CA 1 ATOM 8408 C C . SER A 1 1041 ? 64.729 47.701 -8.959 1.00 12.16 ? 1041 SER A C 1 ATOM 8409 O O . SER A 1 1041 ? 64.705 48.815 -8.425 1.00 12.68 ? 1041 SER A O 1 ATOM 8410 C CB . SER A 1 1041 ? 63.859 47.738 -11.347 1.00 13.44 ? 1041 SER A CB 1 ATOM 8411 O OG . SER A 1 1041 ? 63.890 49.158 -11.413 1.00 13.70 ? 1041 SER A OG 1 ATOM 8412 N N . SER A 1 1042 ? 65.721 46.813 -8.753 1.00 13.21 ? 1042 SER A N 1 ATOM 8413 C CA . SER A 1 1042 ? 66.876 47.103 -7.862 1.00 13.81 ? 1042 SER A CA 1 ATOM 8414 C C . SER A 1 1042 ? 68.107 47.135 -8.773 1.00 12.67 ? 1042 SER A C 1 ATOM 8415 O O . SER A 1 1042 ? 68.188 46.361 -9.728 1.00 16.10 ? 1042 SER A O 1 ATOM 8416 C CB . SER A 1 1042 ? 67.043 45.987 -6.797 1.00 13.03 ? 1042 SER A CB 1 ATOM 8417 O OG . SER A 1 1042 ? 65.906 45.960 -5.935 1.00 15.52 ? 1042 SER A OG 1 ATOM 8418 N N . HIS A 1 1043 ? 69.003 48.087 -8.514 1.00 14.81 ? 1043 HIS A N 1 ATOM 8419 C CA . HIS A 1 1043 ? 70.142 48.347 -9.404 1.00 15.53 ? 1043 HIS A CA 1 ATOM 8420 C C . HIS A 1 1043 ? 71.369 48.474 -8.555 1.00 17.61 ? 1043 HIS A C 1 ATOM 8421 O O . HIS A 1 1043 ? 71.392 49.141 -7.509 1.00 16.36 ? 1043 HIS A O 1 ATOM 8422 C CB . HIS A 1 1043 ? 69.893 49.641 -10.220 1.00 15.94 ? 1043 HIS A CB 1 ATOM 8423 C CG . HIS A 1 1043 ? 68.576 49.652 -10.942 1.00 14.66 ? 1043 HIS A CG 1 ATOM 8424 N ND1 . HIS A 1 1043 ? 68.439 49.196 -12.231 1.00 15.42 ? 1043 HIS A ND1 1 ATOM 8425 C CD2 . HIS A 1 1043 ? 67.308 49.913 -10.498 1.00 12.84 ? 1043 HIS A CD2 1 ATOM 8426 C CE1 . HIS A 1 1043 ? 67.154 49.172 -12.558 1.00 14.33 ? 1043 HIS A CE1 1 ATOM 8427 N NE2 . HIS A 1 1043 ? 66.452 49.598 -11.510 1.00 13.44 ? 1043 HIS A NE2 1 ATOM 8428 N N . SER A 1 1044 ? 72.407 47.811 -9.074 1.00 20.57 ? 1044 SER A N 1 ATOM 8429 C CA . SER A 1 1044 ? 73.661 47.738 -8.371 1.00 28.97 ? 1044 SER A CA 1 ATOM 8430 C C . SER A 1 1044 ? 74.568 48.895 -8.663 1.00 32.44 ? 1044 SER A C 1 ATOM 8431 O O . SER A 1 1044 ? 74.182 49.781 -9.460 1.00 33.17 ? 1044 SER A O 1 ATOM 8432 C CB . SER A 1 1044 ? 74.358 46.398 -8.693 1.00 30.39 ? 1044 SER A CB 1 ATOM 8433 O OG . SER A 1 1044 ? 74.175 45.979 -10.052 1.00 35.88 ? 1044 SER A OG 1 HETATM 8434 C C1 . NAG B 2 . ? 57.883 44.388 13.416 1.00 35.99 ? 2001 NAG A C1 1 HETATM 8435 C C2 . NAG B 2 . ? 59.207 44.131 14.180 1.00 41.69 ? 2001 NAG A C2 1 HETATM 8436 C C3 . NAG B 2 . ? 59.855 42.871 13.628 1.00 43.59 ? 2001 NAG A C3 1 HETATM 8437 C C4 . NAG B 2 . ? 58.729 41.898 13.340 1.00 47.87 ? 2001 NAG A C4 1 HETATM 8438 C C5 . NAG B 2 . ? 58.014 42.406 12.069 1.00 48.58 ? 2001 NAG A C5 1 HETATM 8439 C C6 . NAG B 2 . ? 56.602 41.891 11.895 1.00 50.04 ? 2001 NAG A C6 1 HETATM 8440 C C7 . NAG B 2 . ? 61.208 45.311 13.372 1.00 47.97 ? 2001 NAG A C7 1 HETATM 8441 C C8 . NAG B 2 . ? 62.522 45.121 14.115 1.00 50.68 ? 2001 NAG A C8 1 HETATM 8442 N N2 . NAG B 2 . ? 60.097 45.286 14.110 1.00 44.21 ? 2001 NAG A N2 1 HETATM 8443 O O3 . NAG B 2 . ? 60.746 42.332 14.580 1.00 47.79 ? 2001 NAG A O3 1 HETATM 8444 O O4 . NAG B 2 . ? 59.252 40.594 13.159 1.00 50.79 ? 2001 NAG A O4 1 HETATM 8445 O O5 . NAG B 2 . ? 57.933 43.869 12.085 1.00 45.04 ? 2001 NAG A O5 1 HETATM 8446 O O6 . NAG B 2 . ? 55.896 42.695 10.955 1.00 55.38 ? 2001 NAG A O6 1 HETATM 8447 O O7 . NAG B 2 . ? 61.217 45.508 12.147 1.00 49.84 ? 2001 NAG A O7 1 HETATM 8448 ZN ZN . ZN C 3 . ? 35.068 64.435 8.011 1.00 12.90 ? 2004 ZN A ZN 1 HETATM 8449 C C5 A FMF D 4 . ? 30.387 66.462 7.234 0.50 16.19 ? 2003 FMF A C5 1 HETATM 8450 C C5 B FMF D 4 . ? 30.348 66.473 7.191 0.50 16.32 ? 2003 FMF A C5 1 HETATM 8451 C C2 A FMF D 4 . ? 32.291 65.904 9.036 0.50 12.74 ? 2003 FMF A C2 1 HETATM 8452 C C2 B FMF D 4 . ? 32.306 65.766 8.963 0.50 14.27 ? 2003 FMF A C2 1 HETATM 8453 F F2 A FMF D 4 . ? 33.352 65.369 9.652 0.50 13.97 ? 2003 FMF A F2 1 HETATM 8454 F F2 B FMF D 4 . ? 33.413 65.321 9.637 0.50 18.12 ? 2003 FMF A F2 1 HETATM 8455 C C3 A FMF D 4 . ? 32.701 66.633 7.663 0.50 11.62 ? 2003 FMF A C3 1 HETATM 8456 C C3 B FMF D 4 . ? 32.727 66.689 7.732 0.50 14.05 ? 2003 FMF A C3 1 HETATM 8457 O O3 A FMF D 4 . ? 33.965 66.010 7.223 0.50 6.65 ? 2003 FMF A O3 1 HETATM 8458 O O3 B FMF D 4 . ? 34.068 66.234 7.244 0.50 21.92 ? 2003 FMF A O3 1 HETATM 8459 C C4 A FMF D 4 . ? 31.679 66.665 6.476 0.50 11.53 ? 2003 FMF A C4 1 HETATM 8460 C C4 B FMF D 4 . ? 31.700 66.677 6.490 0.50 13.59 ? 2003 FMF A C4 1 HETATM 8461 O O4 A FMF D 4 . ? 31.796 67.842 5.833 0.50 11.76 ? 2003 FMF A O4 1 HETATM 8462 O O4 B FMF D 4 . ? 31.788 67.880 5.830 0.50 11.63 ? 2003 FMF A O4 1 HETATM 8463 C C6 A FMF D 4 . ? 29.322 66.462 6.229 0.50 15.87 ? 2003 FMF A C6 1 HETATM 8464 C C6 B FMF D 4 . ? 29.242 66.445 6.179 0.50 15.13 ? 2003 FMF A C6 1 HETATM 8465 O O6 A FMF D 4 . ? 28.057 66.586 6.941 0.50 16.61 ? 2003 FMF A O6 1 HETATM 8466 O O6 B FMF D 4 . ? 27.984 66.614 6.894 0.50 14.91 ? 2003 FMF A O6 1 HETATM 8467 O O A FMF D 4 . ? 30.367 65.195 7.850 0.50 13.04 ? 2003 FMF A O 1 HETATM 8468 O O B FMF D 4 . ? 30.306 65.208 7.877 0.50 17.09 ? 2003 FMF A O 1 HETATM 8469 C C1 A FMF D 4 . ? 31.196 64.882 8.897 0.50 14.58 ? 2003 FMF A C1 1 HETATM 8470 C C1 B FMF D 4 . ? 31.525 64.607 8.282 0.50 14.23 ? 2003 FMF A C1 1 HETATM 8471 C C1 . MPD E 5 . ? 14.814 61.183 10.239 1.00 14.50 ? 2002 MPD A C1 1 HETATM 8472 C C2 . MPD E 5 . ? 16.244 61.222 10.572 1.00 16.86 ? 2002 MPD A C2 1 HETATM 8473 O O2 . MPD E 5 . ? 16.920 60.205 9.767 1.00 25.44 ? 2002 MPD A O2 1 HETATM 8474 C CM . MPD E 5 . ? 16.838 62.588 10.203 1.00 22.82 ? 2002 MPD A CM 1 HETATM 8475 C C3 . MPD E 5 . ? 16.315 60.893 12.091 1.00 17.78 ? 2002 MPD A C3 1 HETATM 8476 C C4 . MPD E 5 . ? 17.652 60.690 12.736 1.00 17.64 ? 2002 MPD A C4 1 HETATM 8477 O O4 . MPD E 5 . ? 17.551 59.745 13.827 1.00 15.40 ? 2002 MPD A O4 1 HETATM 8478 C C5 . MPD E 5 . ? 18.180 61.962 13.431 1.00 21.37 ? 2002 MPD A C5 1 HETATM 8479 O O . HOH F 6 . ? 42.173 63.584 -7.206 1.00 7.46 ? 2005 HOH A O 1 HETATM 8480 O O . HOH F 6 . ? 53.763 64.906 -19.934 1.00 9.42 ? 2006 HOH A O 1 HETATM 8481 O O . HOH F 6 . ? 39.369 62.970 -19.199 1.00 8.62 ? 2007 HOH A O 1 HETATM 8482 O O . HOH F 6 . ? 52.343 54.167 -4.872 1.00 8.71 ? 2008 HOH A O 1 HETATM 8483 O O . HOH F 6 . ? 56.303 53.474 -0.670 1.00 8.54 ? 2009 HOH A O 1 HETATM 8484 O O . HOH F 6 . ? 31.395 50.002 -24.091 1.00 11.28 ? 2010 HOH A O 1 HETATM 8485 O O . HOH F 6 . ? 49.998 48.517 1.366 1.00 9.68 ? 2011 HOH A O 1 HETATM 8486 O O . HOH F 6 . ? 36.864 57.760 13.456 1.00 10.40 ? 2012 HOH A O 1 HETATM 8487 O O . HOH F 6 . ? 26.916 69.030 -9.265 1.00 9.62 ? 2013 HOH A O 1 HETATM 8488 O O . HOH F 6 . ? 39.336 64.906 -14.792 1.00 11.61 ? 2014 HOH A O 1 HETATM 8489 O O . HOH F 6 . ? 34.371 58.677 -8.793 1.00 8.20 ? 2015 HOH A O 1 HETATM 8490 O O . HOH F 6 . ? 61.229 59.767 -8.291 1.00 8.76 ? 2016 HOH A O 1 HETATM 8491 O O . HOH F 6 . ? 36.708 72.726 0.250 1.00 9.51 ? 2017 HOH A O 1 HETATM 8492 O O . HOH F 6 . ? 31.845 47.114 -8.099 1.00 8.97 ? 2018 HOH A O 1 HETATM 8493 O O . HOH F 6 . ? 30.217 55.848 17.308 1.00 9.83 ? 2019 HOH A O 1 HETATM 8494 O O . HOH F 6 . ? 26.189 49.701 -13.713 1.00 9.22 ? 2020 HOH A O 1 HETATM 8495 O O . HOH F 6 . ? 37.719 52.213 -21.185 1.00 11.76 ? 2021 HOH A O 1 HETATM 8496 O O . HOH F 6 . ? 33.208 62.871 0.073 1.00 7.88 ? 2022 HOH A O 1 HETATM 8497 O O . HOH F 6 . ? 24.823 53.006 -11.755 1.00 9.73 ? 2023 HOH A O 1 HETATM 8498 O O . HOH F 6 . ? 63.311 61.406 -7.642 1.00 10.27 ? 2024 HOH A O 1 HETATM 8499 O O . HOH F 6 . ? 41.321 59.174 13.379 1.00 12.67 ? 2025 HOH A O 1 HETATM 8500 O O . HOH F 6 . ? 47.419 55.813 -15.450 1.00 16.20 ? 2026 HOH A O 1 HETATM 8501 O O . HOH F 6 . ? 56.525 55.814 -2.151 1.00 10.95 ? 2027 HOH A O 1 HETATM 8502 O O . HOH F 6 . ? 67.689 60.741 -5.733 1.00 13.19 ? 2028 HOH A O 1 HETATM 8503 O O . HOH F 6 . ? 26.371 48.989 -10.975 1.00 10.24 ? 2029 HOH A O 1 HETATM 8504 O O . HOH F 6 . ? 65.817 60.377 -7.773 1.00 10.99 ? 2030 HOH A O 1 HETATM 8505 O O . HOH F 6 . ? 32.694 60.203 -1.805 1.00 9.01 ? 2031 HOH A O 1 HETATM 8506 O O . HOH F 6 . ? 20.051 54.787 16.222 1.00 11.61 ? 2032 HOH A O 1 HETATM 8507 O O . HOH F 6 . ? 23.841 55.604 -23.445 1.00 10.27 ? 2033 HOH A O 1 HETATM 8508 O O . HOH F 6 . ? 39.390 57.490 14.843 1.00 9.89 ? 2034 HOH A O 1 HETATM 8509 O O . HOH F 6 . ? 20.401 58.863 -22.028 1.00 10.82 ? 2035 HOH A O 1 HETATM 8510 O O . HOH F 6 . ? 27.960 61.034 19.576 1.00 11.54 ? 2036 HOH A O 1 HETATM 8511 O O . HOH F 6 . ? 34.204 56.406 -26.378 1.00 10.77 ? 2037 HOH A O 1 HETATM 8512 O O . HOH F 6 . ? 26.344 40.153 7.949 1.00 11.82 ? 2038 HOH A O 1 HETATM 8513 O O . HOH F 6 . ? 63.962 50.189 -14.089 1.00 13.38 ? 2039 HOH A O 1 HETATM 8514 O O . HOH F 6 . ? 37.616 57.135 1.767 1.00 9.89 ? 2040 HOH A O 1 HETATM 8515 O O . HOH F 6 . ? 24.097 42.038 6.897 1.00 10.97 ? 2041 HOH A O 1 HETATM 8516 O O . HOH F 6 . ? 31.895 65.640 19.074 1.00 16.95 ? 2042 HOH A O 1 HETATM 8517 O O . HOH F 6 . ? 51.603 56.759 -5.636 1.00 9.80 ? 2043 HOH A O 1 HETATM 8518 O O . HOH F 6 . ? 20.111 56.086 7.133 1.00 13.30 ? 2044 HOH A O 1 HETATM 8519 O O . HOH F 6 . ? 28.326 43.951 13.224 1.00 10.91 ? 2045 HOH A O 1 HETATM 8520 O O . HOH F 6 . ? 30.299 58.559 -11.820 1.00 8.79 ? 2046 HOH A O 1 HETATM 8521 O O . HOH F 6 . ? 65.062 59.324 -3.661 1.00 14.54 ? 2047 HOH A O 1 HETATM 8522 O O . HOH F 6 . ? 46.584 67.752 -15.626 1.00 14.89 ? 2048 HOH A O 1 HETATM 8523 O O . HOH F 6 . ? 60.933 58.351 -2.886 1.00 11.81 ? 2049 HOH A O 1 HETATM 8524 O O . HOH F 6 . ? 60.693 62.290 -1.304 1.00 12.26 ? 2050 HOH A O 1 HETATM 8525 O O . HOH F 6 . ? 53.850 59.948 -9.454 1.00 12.50 ? 2051 HOH A O 1 HETATM 8526 O O . HOH F 6 . ? 18.699 51.138 -12.464 1.00 12.55 ? 2052 HOH A O 1 HETATM 8527 O O . HOH F 6 . ? 28.945 42.823 -11.940 1.00 10.83 ? 2053 HOH A O 1 HETATM 8528 O O . HOH F 6 . ? 34.656 79.253 -9.168 1.00 12.56 ? 2054 HOH A O 1 HETATM 8529 O O . HOH F 6 . ? 21.621 58.060 -7.821 1.00 10.36 ? 2055 HOH A O 1 HETATM 8530 O O . HOH F 6 . ? 37.180 71.994 -4.577 1.00 8.90 ? 2056 HOH A O 1 HETATM 8531 O O . HOH F 6 . ? 55.741 59.434 -11.523 1.00 9.19 ? 2057 HOH A O 1 HETATM 8532 O O . HOH F 6 . ? 36.828 45.050 -5.483 1.00 10.05 ? 2058 HOH A O 1 HETATM 8533 O O . HOH F 6 . ? 51.401 53.353 -24.010 1.00 12.39 ? 2059 HOH A O 1 HETATM 8534 O O . HOH F 6 . ? 35.251 50.659 -17.604 1.00 15.17 ? 2060 HOH A O 1 HETATM 8535 O O . HOH F 6 . ? 60.741 54.835 -0.418 1.00 13.73 ? 2061 HOH A O 1 HETATM 8536 O O . HOH F 6 . ? 43.104 56.882 6.126 1.00 11.20 ? 2062 HOH A O 1 HETATM 8537 O O . HOH F 6 . ? 47.969 59.356 -25.762 1.00 12.76 ? 2063 HOH A O 1 HETATM 8538 O O . HOH F 6 . ? 37.967 73.421 -2.242 1.00 11.25 ? 2064 HOH A O 1 HETATM 8539 O O . HOH F 6 . ? 19.368 55.323 11.569 1.00 12.73 ? 2065 HOH A O 1 HETATM 8540 O O . HOH F 6 . ? 25.933 39.813 5.248 1.00 10.77 ? 2066 HOH A O 1 HETATM 8541 O O . HOH F 6 . ? 23.423 54.071 -3.626 1.00 14.31 ? 2067 HOH A O 1 HETATM 8542 O O . HOH F 6 . ? 34.359 52.520 -0.955 1.00 9.18 ? 2068 HOH A O 1 HETATM 8543 O O . HOH F 6 . ? 51.166 44.326 -8.026 1.00 11.43 ? 2069 HOH A O 1 HETATM 8544 O O . HOH F 6 . ? 16.487 49.086 24.116 1.00 15.57 ? 2070 HOH A O 1 HETATM 8545 O O . HOH F 6 . ? 19.390 53.576 8.176 1.00 11.54 ? 2071 HOH A O 1 HETATM 8546 O O . HOH F 6 . ? 11.811 51.531 14.278 1.00 15.61 ? 2072 HOH A O 1 HETATM 8547 O O . HOH F 6 . ? 17.056 56.296 10.272 1.00 13.34 ? 2073 HOH A O 1 HETATM 8548 O O . HOH F 6 . ? 68.186 65.664 -3.488 1.00 15.22 ? 2074 HOH A O 1 HETATM 8549 O O . HOH F 6 . ? 22.921 53.134 -24.468 1.00 13.29 ? 2075 HOH A O 1 HETATM 8550 O O . HOH F 6 . ? 52.301 50.637 6.357 1.00 11.83 ? 2076 HOH A O 1 HETATM 8551 O O . HOH F 6 . ? 17.652 52.807 6.307 1.00 11.37 ? 2077 HOH A O 1 HETATM 8552 O O . HOH F 6 . ? 69.020 58.325 -5.135 1.00 14.03 ? 2078 HOH A O 1 HETATM 8553 O O . HOH F 6 . ? 33.599 48.223 -10.150 1.00 9.42 ? 2079 HOH A O 1 HETATM 8554 O O . HOH F 6 . ? 26.816 41.626 -13.224 1.00 13.33 ? 2080 HOH A O 1 HETATM 8555 O O . HOH F 6 . ? 26.862 60.992 -3.344 1.00 9.69 ? 2081 HOH A O 1 HETATM 8556 O O . HOH F 6 . ? 49.749 62.356 -8.696 1.00 11.11 ? 2082 HOH A O 1 HETATM 8557 O O . HOH F 6 . ? 41.195 52.432 -16.984 1.00 12.69 ? 2083 HOH A O 1 HETATM 8558 O O . HOH F 6 . ? 31.505 76.921 -6.374 1.00 11.77 ? 2084 HOH A O 1 HETATM 8559 O O . HOH F 6 . ? 43.511 68.351 -25.078 1.00 14.91 ? 2085 HOH A O 1 HETATM 8560 O O . HOH F 6 . ? 32.880 81.192 -11.746 1.00 11.10 ? 2086 HOH A O 1 HETATM 8561 O O . HOH F 6 . ? 20.628 66.272 -19.669 1.00 13.21 ? 2087 HOH A O 1 HETATM 8562 O O . HOH F 6 . ? 40.559 62.885 6.067 1.00 9.43 ? 2088 HOH A O 1 HETATM 8563 O O . HOH F 6 . ? 42.310 47.368 -24.608 1.00 13.85 ? 2089 HOH A O 1 HETATM 8564 O O . HOH F 6 . ? 44.642 41.911 -0.486 1.00 14.76 ? 2090 HOH A O 1 HETATM 8565 O O . HOH F 6 . ? 38.789 55.241 -31.805 1.00 16.24 ? 2091 HOH A O 1 HETATM 8566 O O . HOH F 6 . ? 22.397 54.465 -12.039 1.00 11.56 ? 2092 HOH A O 1 HETATM 8567 O O . HOH F 6 . ? 48.395 89.325 -30.824 1.00 16.04 ? 2093 HOH A O 1 HETATM 8568 O O . HOH F 6 . ? 36.804 51.788 3.810 1.00 12.11 ? 2094 HOH A O 1 HETATM 8569 O O . HOH F 6 . ? 38.990 62.286 8.285 1.00 11.58 ? 2095 HOH A O 1 HETATM 8570 O O . HOH F 6 . ? 47.615 46.036 3.680 1.00 10.52 ? 2096 HOH A O 1 HETATM 8571 O O . HOH F 6 . ? 33.651 57.124 -36.014 1.00 17.35 ? 2097 HOH A O 1 HETATM 8572 O O . HOH F 6 . ? 32.469 77.752 -29.724 1.00 13.89 ? 2098 HOH A O 1 HETATM 8573 O O . HOH F 6 . ? 39.327 39.014 17.362 1.00 17.18 ? 2099 HOH A O 1 HETATM 8574 O O . HOH F 6 . ? 36.060 53.216 1.343 1.00 11.90 ? 2100 HOH A O 1 HETATM 8575 O O . HOH F 6 . ? 14.466 60.134 5.188 1.00 13.72 ? 2101 HOH A O 1 HETATM 8576 O O . HOH F 6 . ? 21.719 57.214 5.013 1.00 12.26 ? 2102 HOH A O 1 HETATM 8577 O O . HOH F 6 . ? 43.161 48.136 11.233 1.00 14.30 ? 2103 HOH A O 1 HETATM 8578 O O . HOH F 6 . ? 26.193 72.813 5.606 1.00 13.22 ? 2104 HOH A O 1 HETATM 8579 O O . HOH F 6 . ? 27.590 48.548 -21.697 1.00 17.03 ? 2105 HOH A O 1 HETATM 8580 O O . HOH F 6 . ? 33.486 78.737 -5.161 1.00 12.33 ? 2106 HOH A O 1 HETATM 8581 O O . HOH F 6 . ? 50.163 59.592 -11.581 1.00 11.87 ? 2107 HOH A O 1 HETATM 8582 O O . HOH F 6 . ? 25.624 51.321 -9.524 1.00 12.69 ? 2108 HOH A O 1 HETATM 8583 O O . HOH F 6 . ? 40.270 56.358 5.793 1.00 12.42 ? 2109 HOH A O 1 HETATM 8584 O O . HOH F 6 . ? 14.150 59.815 -3.429 1.00 16.19 ? 2110 HOH A O 1 HETATM 8585 O O . HOH F 6 . ? 19.765 53.642 -11.802 1.00 11.56 ? 2111 HOH A O 1 HETATM 8586 O O . HOH F 6 . ? 26.352 63.774 17.138 1.00 21.00 ? 2112 HOH A O 1 HETATM 8587 O O . HOH F 6 . ? 19.914 57.490 -11.803 1.00 15.19 ? 2113 HOH A O 1 HETATM 8588 O O . HOH F 6 . ? 47.153 48.601 11.559 1.00 17.34 ? 2114 HOH A O 1 HETATM 8589 O O . HOH F 6 . ? 67.975 81.769 -25.784 1.00 14.03 ? 2115 HOH A O 1 HETATM 8590 O O . HOH F 6 . ? 23.083 51.867 -8.581 1.00 17.31 ? 2116 HOH A O 1 HETATM 8591 O O . HOH F 6 . ? 46.706 70.392 -36.825 1.00 16.54 ? 2117 HOH A O 1 HETATM 8592 O O . HOH F 6 . ? 20.687 57.501 -5.280 1.00 11.18 ? 2118 HOH A O 1 HETATM 8593 O O . HOH F 6 . ? 18.062 60.703 24.500 1.00 17.52 ? 2119 HOH A O 1 HETATM 8594 O O . HOH F 6 . ? 41.370 68.472 -32.648 1.00 15.13 ? 2120 HOH A O 1 HETATM 8595 O O . HOH F 6 . ? 38.419 40.147 1.732 1.00 12.87 ? 2121 HOH A O 1 HETATM 8596 O O . HOH F 6 . ? 23.899 58.233 6.317 1.00 12.57 ? 2122 HOH A O 1 HETATM 8597 O O . HOH F 6 . ? 18.243 59.859 -20.089 1.00 17.96 ? 2123 HOH A O 1 HETATM 8598 O O . HOH F 6 . ? 41.409 77.676 -14.163 1.00 13.30 ? 2124 HOH A O 1 HETATM 8599 O O . HOH F 6 . ? 52.945 58.994 -1.789 1.00 13.96 ? 2125 HOH A O 1 HETATM 8600 O O . HOH F 6 . ? 48.065 49.640 13.839 1.00 12.78 ? 2126 HOH A O 1 HETATM 8601 O O . HOH F 6 . ? 35.243 43.672 28.754 1.00 14.59 ? 2127 HOH A O 1 HETATM 8602 O O . HOH F 6 . ? 59.651 60.678 -6.273 1.00 13.58 ? 2128 HOH A O 1 HETATM 8603 O O . HOH F 6 . ? 53.787 72.723 -19.312 1.00 14.60 ? 2129 HOH A O 1 HETATM 8604 O O . HOH F 6 . ? 39.830 54.021 -20.845 1.00 15.37 ? 2130 HOH A O 1 HETATM 8605 O O . HOH F 6 . ? 33.369 36.741 -4.414 1.00 16.07 ? 2131 HOH A O 1 HETATM 8606 O O . HOH F 6 . ? 14.476 63.988 -16.388 1.00 16.82 ? 2132 HOH A O 1 HETATM 8607 O O . HOH F 6 . ? 47.572 43.081 -2.408 1.00 14.91 ? 2133 HOH A O 1 HETATM 8608 O O . HOH F 6 . ? 47.011 55.871 -25.557 1.00 14.23 ? 2134 HOH A O 1 HETATM 8609 O O . HOH F 6 . ? 32.190 58.691 -28.543 1.00 13.97 ? 2135 HOH A O 1 HETATM 8610 O O . HOH F 6 . ? 49.358 50.105 28.294 1.00 15.86 ? 2136 HOH A O 1 HETATM 8611 O O . HOH F 6 . ? 26.363 37.413 29.432 1.00 18.76 ? 2137 HOH A O 1 HETATM 8612 O O . HOH F 6 . ? 52.020 46.615 1.305 1.00 11.27 ? 2138 HOH A O 1 HETATM 8613 O O . HOH F 6 . ? 41.794 58.816 -16.066 1.00 15.21 ? 2139 HOH A O 1 HETATM 8614 O O . HOH F 6 . ? 13.868 54.214 4.373 1.00 15.76 ? 2140 HOH A O 1 HETATM 8615 O O . HOH F 6 . ? 67.954 79.004 -25.408 1.00 13.22 ? 2141 HOH A O 1 HETATM 8616 O O . HOH F 6 . ? 42.281 75.382 -16.035 1.00 13.56 ? 2142 HOH A O 1 HETATM 8617 O O . HOH F 6 . ? 23.076 56.098 30.923 1.00 16.50 ? 2143 HOH A O 1 HETATM 8618 O O . HOH F 6 . ? 57.135 61.121 1.552 1.00 15.83 ? 2144 HOH A O 1 HETATM 8619 O O . HOH F 6 . ? 20.160 74.447 -6.840 1.00 13.45 ? 2145 HOH A O 1 HETATM 8620 O O . HOH F 6 . ? 13.480 53.620 1.792 1.00 18.02 ? 2146 HOH A O 1 HETATM 8621 O O . HOH F 6 . ? 34.382 34.443 16.228 1.00 20.54 ? 2147 HOH A O 1 HETATM 8622 O O . HOH F 6 . ? 34.000 64.603 -32.368 1.00 13.98 ? 2148 HOH A O 1 HETATM 8623 O O . HOH F 6 . ? 13.983 49.115 15.363 1.00 16.16 ? 2149 HOH A O 1 HETATM 8624 O O . HOH F 6 . ? 30.404 35.228 -12.415 1.00 23.12 ? 2150 HOH A O 1 HETATM 8625 O O . HOH F 6 . ? 18.330 55.005 14.185 1.00 13.04 ? 2151 HOH A O 1 HETATM 8626 O O . HOH F 6 . ? 15.476 60.416 15.486 1.00 15.84 ? 2152 HOH A O 1 HETATM 8627 O O . HOH F 6 . ? 16.938 74.709 -3.014 1.00 14.57 ? 2153 HOH A O 1 HETATM 8628 O O . HOH F 6 . ? 56.681 46.253 -17.421 1.00 16.17 ? 2154 HOH A O 1 HETATM 8629 O O . HOH F 6 . ? 45.808 60.015 -18.305 1.00 13.41 ? 2155 HOH A O 1 HETATM 8630 O O . HOH F 6 . ? 28.108 84.680 -35.558 1.00 16.18 ? 2156 HOH A O 1 HETATM 8631 O O . HOH F 6 . ? 73.209 65.107 -7.870 1.00 22.40 ? 2157 HOH A O 1 HETATM 8632 O O . HOH F 6 . ? 74.083 65.991 -17.686 1.00 16.44 ? 2158 HOH A O 1 HETATM 8633 O O . HOH F 6 . ? 59.458 50.042 -0.687 1.00 15.44 ? 2159 HOH A O 1 HETATM 8634 O O . HOH F 6 . ? 23.260 78.494 -24.875 1.00 17.26 ? 2160 HOH A O 1 HETATM 8635 O O . HOH F 6 . ? 14.367 54.482 -16.172 1.00 18.61 ? 2161 HOH A O 1 HETATM 8636 O O . HOH F 6 . ? 43.696 73.247 5.800 1.00 12.12 ? 2162 HOH A O 1 HETATM 8637 O O . HOH F 6 . ? 11.835 55.117 -12.425 1.00 18.67 ? 2163 HOH A O 1 HETATM 8638 O O . HOH F 6 . ? 63.727 44.698 -6.839 1.00 16.31 ? 2164 HOH A O 1 HETATM 8639 O O . HOH F 6 . ? 24.790 51.162 -24.103 1.00 13.78 ? 2165 HOH A O 1 HETATM 8640 O O . HOH F 6 . ? 35.685 45.295 -27.476 1.00 16.71 ? 2166 HOH A O 1 HETATM 8641 O O . HOH F 6 . ? 28.740 49.786 -24.480 1.00 16.38 ? 2167 HOH A O 1 HETATM 8642 O O . HOH F 6 . ? 55.056 81.158 -23.692 1.00 14.50 ? 2168 HOH A O 1 HETATM 8643 O O . HOH F 6 . ? 24.211 63.559 7.509 1.00 12.10 ? 2169 HOH A O 1 HETATM 8644 O O . HOH F 6 . ? 49.925 57.711 -7.617 1.00 11.42 ? 2170 HOH A O 1 HETATM 8645 O O . HOH F 6 . ? 46.226 71.014 0.045 1.00 15.59 ? 2171 HOH A O 1 HETATM 8646 O O . HOH F 6 . ? 24.458 55.781 -1.743 1.00 12.55 ? 2172 HOH A O 1 HETATM 8647 O O . HOH F 6 . ? 28.675 41.351 -21.721 1.00 14.03 ? 2173 HOH A O 1 HETATM 8648 O O . HOH F 6 . ? 37.147 45.613 27.513 1.00 13.78 ? 2174 HOH A O 1 HETATM 8649 O O . HOH F 6 . ? 41.671 41.274 -17.631 1.00 18.46 ? 2175 HOH A O 1 HETATM 8650 O O . HOH F 6 . ? 40.357 62.574 -32.063 1.00 17.50 ? 2176 HOH A O 1 HETATM 8651 O O . HOH F 6 . ? 49.354 59.365 -28.771 1.00 18.47 ? 2177 HOH A O 1 HETATM 8652 O O . HOH F 6 . ? 64.502 39.391 -10.429 1.00 23.13 ? 2178 HOH A O 1 HETATM 8653 O O . HOH F 6 . ? 19.250 72.560 2.933 1.00 16.77 ? 2179 HOH A O 1 HETATM 8654 O O . HOH F 6 . ? 17.143 70.432 -16.363 1.00 13.29 ? 2180 HOH A O 1 HETATM 8655 O O . HOH F 6 . ? 9.390 52.497 16.849 1.00 19.88 ? 2181 HOH A O 1 HETATM 8656 O O . HOH F 6 . ? 54.039 71.369 -36.966 1.00 13.14 ? 2182 HOH A O 1 HETATM 8657 O O . HOH F 6 . ? 51.015 70.951 -23.641 1.00 17.13 ? 2183 HOH A O 1 HETATM 8658 O O . HOH F 6 . ? 49.523 44.240 4.437 1.00 14.21 ? 2184 HOH A O 1 HETATM 8659 O O . HOH F 6 . ? 59.521 68.315 2.468 1.00 25.12 ? 2185 HOH A O 1 HETATM 8660 O O . HOH F 6 . ? 25.529 53.875 11.050 1.00 15.59 ? 2186 HOH A O 1 HETATM 8661 O O . HOH F 6 . ? 69.339 61.475 -2.456 1.00 15.40 ? 2187 HOH A O 1 HETATM 8662 O O . HOH F 6 . ? 58.480 77.351 -38.608 1.00 13.99 ? 2188 HOH A O 1 HETATM 8663 O O . HOH F 6 . ? 44.544 46.119 10.038 1.00 15.74 ? 2189 HOH A O 1 HETATM 8664 O O . HOH F 6 . ? 46.700 57.408 -18.806 1.00 13.56 ? 2190 HOH A O 1 HETATM 8665 O O . HOH F 6 . ? 33.689 83.691 -10.453 1.00 15.12 ? 2191 HOH A O 1 HETATM 8666 O O . HOH F 6 . ? 47.246 68.615 -30.369 1.00 15.78 ? 2192 HOH A O 1 HETATM 8667 O O . HOH F 6 . ? 44.626 56.148 -15.407 1.00 16.39 ? 2193 HOH A O 1 HETATM 8668 O O . HOH F 6 . ? 13.207 66.924 -4.806 1.00 15.32 ? 2194 HOH A O 1 HETATM 8669 O O . HOH F 6 . ? 24.530 39.208 -11.554 1.00 22.02 ? 2195 HOH A O 1 HETATM 8670 O O . HOH F 6 . ? 41.716 61.302 -29.837 1.00 16.24 ? 2196 HOH A O 1 HETATM 8671 O O . HOH F 6 . ? 27.279 41.436 13.319 1.00 14.31 ? 2197 HOH A O 1 HETATM 8672 O O . HOH F 6 . ? 42.193 87.874 -41.013 1.00 16.79 ? 2198 HOH A O 1 HETATM 8673 O O . HOH F 6 . ? 70.190 69.982 -12.742 1.00 14.25 ? 2199 HOH A O 1 HETATM 8674 O O . HOH F 6 . ? 64.419 77.984 -35.421 1.00 14.54 ? 2200 HOH A O 1 HETATM 8675 O O . HOH F 6 . ? 20.834 65.480 7.789 1.00 15.98 ? 2201 HOH A O 1 HETATM 8676 O O . HOH F 6 . ? 11.446 61.414 -18.372 1.00 21.01 ? 2202 HOH A O 1 HETATM 8677 O O . HOH F 6 . ? 24.720 70.659 -8.758 1.00 12.83 ? 2203 HOH A O 1 HETATM 8678 O O . HOH F 6 . ? 25.032 40.028 14.230 1.00 15.97 ? 2204 HOH A O 1 HETATM 8679 O O . HOH F 6 . ? 22.655 63.403 -33.190 1.00 21.75 ? 2205 HOH A O 1 HETATM 8680 O O . HOH F 6 . ? 41.831 43.302 8.075 1.00 18.33 ? 2206 HOH A O 1 HETATM 8681 O O . HOH F 6 . ? 20.925 51.906 47.594 1.00 17.11 ? 2207 HOH A O 1 HETATM 8682 O O . HOH F 6 . ? 41.400 50.462 33.324 1.00 27.50 ? 2208 HOH A O 1 HETATM 8683 O O . HOH F 6 . ? 46.135 52.822 -19.188 1.00 19.07 ? 2209 HOH A O 1 HETATM 8684 O O . HOH F 6 . ? 51.568 76.434 -41.091 1.00 27.79 ? 2210 HOH A O 1 HETATM 8685 O O . HOH F 6 . ? 25.665 86.242 -31.985 1.00 18.24 ? 2211 HOH A O 1 HETATM 8686 O O . HOH F 6 . ? 12.521 56.361 5.349 1.00 16.31 ? 2212 HOH A O 1 HETATM 8687 O O . HOH F 6 . ? 22.524 56.862 -34.237 1.00 19.20 ? 2213 HOH A O 1 HETATM 8688 O O . HOH F 6 . ? 43.933 72.605 -42.009 1.00 21.35 ? 2214 HOH A O 1 HETATM 8689 O O . HOH F 6 . ? 44.654 58.811 -16.007 1.00 15.07 ? 2215 HOH A O 1 HETATM 8690 O O . HOH F 6 . ? 31.489 81.865 0.467 1.00 18.01 ? 2216 HOH A O 1 HETATM 8691 O O . HOH F 6 . ? 52.226 56.406 -30.424 1.00 21.23 ? 2217 HOH A O 1 HETATM 8692 O O . HOH F 6 . ? 17.370 70.242 -23.475 1.00 19.83 ? 2218 HOH A O 1 HETATM 8693 O O . HOH F 6 . ? 37.633 47.082 29.840 1.00 21.71 ? 2219 HOH A O 1 HETATM 8694 O O . HOH F 6 . ? 49.925 55.124 -29.142 1.00 16.36 ? 2220 HOH A O 1 HETATM 8695 O O . HOH F 6 . ? 36.430 79.331 -5.054 1.00 20.98 ? 2221 HOH A O 1 HETATM 8696 O O . HOH F 6 . ? 62.251 62.613 25.836 1.00 18.10 ? 2222 HOH A O 1 HETATM 8697 O O . HOH F 6 . ? 11.401 53.224 6.791 1.00 15.91 ? 2223 HOH A O 1 HETATM 8698 O O . HOH F 6 . ? 13.929 60.930 -22.505 1.00 16.37 ? 2224 HOH A O 1 HETATM 8699 O O . HOH F 6 . ? 50.763 62.008 26.452 1.00 19.73 ? 2225 HOH A O 1 HETATM 8700 O O . HOH F 6 . ? 68.756 78.944 -18.248 1.00 21.06 ? 2226 HOH A O 1 HETATM 8701 O O . HOH F 6 . ? 84.506 68.363 -17.347 1.00 18.12 ? 2227 HOH A O 1 HETATM 8702 O O . HOH F 6 . ? 22.072 40.336 -8.757 1.00 26.30 ? 2228 HOH A O 1 HETATM 8703 O O . HOH F 6 . ? 52.996 69.689 18.342 1.00 27.23 ? 2229 HOH A O 1 HETATM 8704 O O . HOH F 6 . ? 42.836 53.353 35.668 1.00 22.66 ? 2230 HOH A O 1 HETATM 8705 O O . HOH F 6 . ? 70.742 52.134 -12.731 1.00 20.70 ? 2231 HOH A O 1 HETATM 8706 O O . HOH F 6 . ? 34.634 71.384 13.335 1.00 21.92 ? 2232 HOH A O 1 HETATM 8707 O O . HOH F 6 . ? 27.280 46.435 13.699 1.00 13.59 ? 2233 HOH A O 1 HETATM 8708 O O . HOH F 6 . ? 14.231 49.836 19.801 1.00 18.21 ? 2234 HOH A O 1 HETATM 8709 O O . HOH F 6 . ? 49.942 73.509 -21.880 1.00 25.83 ? 2235 HOH A O 1 HETATM 8710 O O . HOH F 6 . ? 48.901 44.284 -6.172 1.00 17.88 ? 2236 HOH A O 1 HETATM 8711 O O . HOH F 6 . ? 61.519 76.789 -39.903 1.00 21.53 ? 2237 HOH A O 1 HETATM 8712 O O . HOH F 6 . ? 22.898 78.729 -30.427 1.00 22.21 ? 2238 HOH A O 1 HETATM 8713 O O . HOH F 6 . ? 43.674 88.520 -38.755 1.00 16.42 ? 2239 HOH A O 1 HETATM 8714 O O . HOH F 6 . ? 35.917 77.657 -7.360 1.00 13.84 ? 2240 HOH A O 1 HETATM 8715 O O . HOH F 6 . ? 24.768 68.449 21.989 1.00 20.45 ? 2241 HOH A O 1 HETATM 8716 O O . HOH F 6 . ? 68.302 49.394 -1.058 1.00 23.25 ? 2242 HOH A O 1 HETATM 8717 O O . HOH F 6 . ? 54.313 47.808 15.581 1.00 21.55 ? 2243 HOH A O 1 HETATM 8718 O O . HOH F 6 . ? 55.298 50.365 16.924 1.00 26.90 ? 2244 HOH A O 1 HETATM 8719 O O . HOH F 6 . ? 39.539 48.879 -33.007 1.00 24.63 ? 2245 HOH A O 1 HETATM 8720 O O . HOH F 6 . ? 22.651 45.403 -13.499 1.00 17.14 ? 2246 HOH A O 1 HETATM 8721 O O . HOH F 6 . ? 67.345 55.276 0.930 1.00 16.14 ? 2247 HOH A O 1 HETATM 8722 O O . HOH F 6 . ? 48.104 44.032 -8.675 1.00 19.72 ? 2248 HOH A O 1 HETATM 8723 O O . HOH F 6 . ? 26.966 87.838 -23.750 1.00 22.60 ? 2249 HOH A O 1 HETATM 8724 O O . HOH F 6 . ? 18.818 48.747 37.694 1.00 18.09 ? 2250 HOH A O 1 HETATM 8725 O O . HOH F 6 . ? 83.757 67.722 -22.829 1.00 26.68 ? 2251 HOH A O 1 HETATM 8726 O O . HOH F 6 . ? 43.074 59.569 -18.894 1.00 23.45 ? 2252 HOH A O 1 HETATM 8727 O O . HOH F 6 . ? 47.554 79.167 -40.533 1.00 18.76 ? 2253 HOH A O 1 HETATM 8728 O O . HOH F 6 . ? 8.661 57.761 -6.836 1.00 24.58 ? 2254 HOH A O 1 HETATM 8729 O O . HOH F 6 . ? 54.966 90.383 -23.605 1.00 27.94 ? 2255 HOH A O 1 HETATM 8730 O O . HOH F 6 . ? 27.744 36.515 -19.691 1.00 24.66 ? 2256 HOH A O 1 HETATM 8731 O O . HOH F 6 . ? 72.416 58.850 -11.287 1.00 22.34 ? 2257 HOH A O 1 HETATM 8732 O O . HOH F 6 . ? 11.844 59.534 -5.016 1.00 21.71 ? 2258 HOH A O 1 HETATM 8733 O O . HOH F 6 . ? 23.681 46.056 -15.900 1.00 20.35 ? 2259 HOH A O 1 HETATM 8734 O O . HOH F 6 . ? 50.179 70.881 -17.665 1.00 24.63 ? 2260 HOH A O 1 HETATM 8735 O O . HOH F 6 . ? 45.298 90.159 -25.586 1.00 19.85 ? 2261 HOH A O 1 HETATM 8736 O O . HOH F 6 . ? 16.121 72.193 -19.110 1.00 19.17 ? 2262 HOH A O 1 HETATM 8737 O O . HOH F 6 . ? 20.191 52.732 -24.328 1.00 18.00 ? 2263 HOH A O 1 HETATM 8738 O O . HOH F 6 . ? 59.664 76.618 -9.042 1.00 17.25 ? 2264 HOH A O 1 HETATM 8739 O O . HOH F 6 . ? 67.027 60.043 -27.208 1.00 21.28 ? 2265 HOH A O 1 HETATM 8740 O O . HOH F 6 . ? 38.607 51.382 -29.818 1.00 28.70 ? 2266 HOH A O 1 HETATM 8741 O O . HOH F 6 . ? 40.518 82.920 -10.719 1.00 16.30 ? 2267 HOH A O 1 HETATM 8742 O O . HOH F 6 . ? 42.197 48.901 31.303 1.00 19.83 ? 2268 HOH A O 1 HETATM 8743 O O . HOH F 6 . ? 24.269 53.287 -6.248 1.00 18.56 ? 2269 HOH A O 1 HETATM 8744 O O . HOH F 6 . ? 53.408 47.141 -25.112 1.00 17.47 ? 2270 HOH A O 1 HETATM 8745 O O . HOH F 6 . ? 32.589 89.261 -43.155 1.00 22.67 ? 2271 HOH A O 1 HETATM 8746 O O . HOH F 6 . ? 36.081 36.150 -4.588 1.00 20.16 ? 2272 HOH A O 1 HETATM 8747 O O . HOH F 6 . ? 70.181 83.085 -29.980 1.00 22.71 ? 2273 HOH A O 1 HETATM 8748 O O . HOH F 6 . ? 49.900 82.519 -43.992 1.00 20.44 ? 2274 HOH A O 1 HETATM 8749 O O . HOH F 6 . ? 68.536 79.734 -34.954 1.00 24.55 ? 2275 HOH A O 1 HETATM 8750 O O . HOH F 6 . ? 29.144 46.993 37.189 1.00 22.17 ? 2276 HOH A O 1 HETATM 8751 O O . HOH F 6 . ? 18.596 70.077 4.178 1.00 14.67 ? 2277 HOH A O 1 HETATM 8752 O O . HOH F 6 . ? 14.129 68.377 -7.874 1.00 19.61 ? 2278 HOH A O 1 HETATM 8753 O O . HOH F 6 . ? 50.556 72.494 9.194 1.00 26.29 ? 2279 HOH A O 1 HETATM 8754 O O . HOH F 6 . ? 39.686 75.681 -40.367 1.00 17.36 ? 2280 HOH A O 1 HETATM 8755 O O . HOH F 6 . ? 28.625 65.249 19.844 1.00 17.63 ? 2281 HOH A O 1 HETATM 8756 O O . HOH F 6 . ? 11.669 58.799 7.898 1.00 24.48 ? 2282 HOH A O 1 HETATM 8757 O O . HOH F 6 . ? 52.682 79.170 -17.594 1.00 24.37 ? 2283 HOH A O 1 HETATM 8758 O O . HOH F 6 . ? 18.484 65.123 -27.036 1.00 20.84 ? 2284 HOH A O 1 HETATM 8759 O O . HOH F 6 . ? 44.812 79.413 -33.347 1.00 21.04 ? 2285 HOH A O 1 HETATM 8760 O O . HOH F 6 . ? 36.254 81.227 6.372 1.00 19.45 ? 2286 HOH A O 1 HETATM 8761 O O . HOH F 6 . ? 16.724 60.726 -28.119 1.00 19.55 ? 2287 HOH A O 1 HETATM 8762 O O . HOH F 6 . ? 29.682 87.413 -17.867 1.00 28.45 ? 2288 HOH A O 1 HETATM 8763 O O . HOH F 6 . ? 8.781 55.123 -6.065 1.00 25.47 ? 2289 HOH A O 1 HETATM 8764 O O . HOH F 6 . ? 46.801 61.764 -26.021 1.00 19.18 ? 2290 HOH A O 1 HETATM 8765 O O . HOH F 6 . ? 43.212 82.381 -10.029 1.00 25.50 ? 2291 HOH A O 1 HETATM 8766 O O . HOH F 6 . ? 10.345 50.729 18.862 1.00 22.09 ? 2292 HOH A O 1 HETATM 8767 O O . HOH F 6 . ? 12.935 42.479 12.529 1.00 21.43 ? 2293 HOH A O 1 HETATM 8768 O O . HOH F 6 . ? 35.962 45.139 30.905 1.00 20.72 ? 2294 HOH A O 1 HETATM 8769 O O . HOH F 6 . ? 15.928 75.327 -11.735 1.00 20.79 ? 2295 HOH A O 1 HETATM 8770 O O . HOH F 6 . ? 25.231 47.041 -20.949 1.00 22.12 ? 2296 HOH A O 1 HETATM 8771 O O . HOH F 6 . ? 56.938 64.953 24.342 1.00 22.53 ? 2297 HOH A O 1 HETATM 8772 O O . HOH F 6 . ? 38.693 94.162 -42.249 1.00 23.88 ? 2298 HOH A O 1 HETATM 8773 O O . HOH F 6 . ? 34.836 59.553 -35.058 1.00 19.06 ? 2299 HOH A O 1 HETATM 8774 O O . HOH F 6 . ? 33.052 40.913 -18.195 1.00 24.34 ? 2300 HOH A O 1 HETATM 8775 O O . HOH F 6 . ? 20.797 42.768 -7.431 1.00 18.47 ? 2301 HOH A O 1 HETATM 8776 O O . HOH F 6 . ? 19.138 76.769 4.783 1.00 27.56 ? 2302 HOH A O 1 HETATM 8777 O O . HOH F 6 . ? 43.507 80.964 4.957 1.00 20.63 ? 2303 HOH A O 1 HETATM 8778 O O . HOH F 6 . ? 32.995 85.483 -5.558 1.00 19.67 ? 2304 HOH A O 1 HETATM 8779 O O . HOH F 6 . ? 31.318 33.677 2.811 1.00 24.46 ? 2305 HOH A O 1 HETATM 8780 O O . HOH F 6 . ? 21.454 78.634 -1.406 1.00 18.15 ? 2306 HOH A O 1 HETATM 8781 O O . HOH F 6 . ? 55.471 59.112 3.895 1.00 17.04 ? 2307 HOH A O 1 HETATM 8782 O O . HOH F 6 . ? 13.418 62.476 -20.067 1.00 19.92 ? 2308 HOH A O 1 HETATM 8783 O O . HOH F 6 . ? 17.065 50.858 -19.358 1.00 23.81 ? 2309 HOH A O 1 HETATM 8784 O O . HOH F 6 . ? 14.257 62.964 -12.132 1.00 20.80 ? 2310 HOH A O 1 HETATM 8785 O O . HOH F 6 . ? 53.318 86.728 -21.475 1.00 24.97 ? 2311 HOH A O 1 HETATM 8786 O O . HOH F 6 . ? 71.165 49.540 -0.119 1.00 22.69 ? 2312 HOH A O 1 HETATM 8787 O O . HOH F 6 . ? 58.162 42.428 1.548 1.00 22.84 ? 2313 HOH A O 1 HETATM 8788 O O . HOH F 6 . ? 74.947 76.650 -14.182 1.00 26.17 ? 2314 HOH A O 1 HETATM 8789 O O . HOH F 6 . ? 24.958 83.237 -16.921 1.00 22.57 ? 2315 HOH A O 1 HETATM 8790 O O . HOH F 6 . ? 56.994 67.747 -35.499 1.00 23.45 ? 2316 HOH A O 1 HETATM 8791 O O . HOH F 6 . ? 48.993 50.779 -29.632 1.00 22.85 ? 2317 HOH A O 1 HETATM 8792 O O . HOH F 6 . ? 66.805 71.619 -6.929 1.00 20.93 ? 2318 HOH A O 1 HETATM 8793 O O . HOH F 6 . ? 28.831 93.901 -38.586 1.00 22.80 ? 2319 HOH A O 1 HETATM 8794 O O . HOH F 6 . ? 32.658 64.891 -10.007 1.00 18.87 ? 2320 HOH A O 1 HETATM 8795 O O . HOH F 6 . ? 13.484 51.005 -1.651 1.00 24.20 ? 2321 HOH A O 1 HETATM 8796 O O . HOH F 6 . ? 39.412 49.292 30.136 1.00 28.31 ? 2322 HOH A O 1 HETATM 8797 O O . HOH F 6 . ? 68.064 58.778 -24.226 1.00 19.74 ? 2323 HOH A O 1 HETATM 8798 O O . HOH F 6 . ? 20.850 59.084 -34.575 1.00 18.49 ? 2324 HOH A O 1 HETATM 8799 O O . HOH F 6 . ? 37.656 75.725 -42.554 1.00 21.72 ? 2325 HOH A O 1 HETATM 8800 O O . HOH F 6 . ? 31.951 51.374 -35.447 1.00 24.05 ? 2326 HOH A O 1 HETATM 8801 O O . HOH F 6 . ? 12.741 71.197 -0.452 1.00 25.95 ? 2327 HOH A O 1 HETATM 8802 O O . HOH F 6 . ? 37.035 41.134 -24.754 1.00 26.86 ? 2328 HOH A O 1 HETATM 8803 O O . HOH F 6 . ? 19.258 42.772 -2.531 1.00 25.96 ? 2329 HOH A O 1 HETATM 8804 O O . HOH F 6 . ? 50.156 44.130 7.081 1.00 18.58 ? 2330 HOH A O 1 HETATM 8805 O O . HOH F 6 . ? 37.500 45.398 -25.498 1.00 21.66 ? 2331 HOH A O 1 HETATM 8806 O O . HOH F 6 . ? 75.506 74.215 -19.499 1.00 24.00 ? 2332 HOH A O 1 HETATM 8807 O O . HOH F 6 . ? 50.440 61.146 -31.237 1.00 18.97 ? 2333 HOH A O 1 HETATM 8808 O O . HOH F 6 . ? 42.963 56.810 -31.642 1.00 22.12 ? 2334 HOH A O 1 HETATM 8809 O O . HOH F 6 . ? 13.266 68.903 0.877 1.00 22.66 ? 2335 HOH A O 1 HETATM 8810 O O . HOH F 6 . ? 40.707 83.005 -31.441 1.00 26.47 ? 2336 HOH A O 1 HETATM 8811 O O . HOH F 6 . ? 27.016 51.697 22.647 1.00 21.89 ? 2337 HOH A O 1 HETATM 8812 O O . HOH F 6 . ? 12.739 66.444 -9.704 1.00 19.59 ? 2338 HOH A O 1 HETATM 8813 O O . HOH F 6 . ? 42.556 39.555 -15.830 1.00 20.76 ? 2339 HOH A O 1 HETATM 8814 O O . HOH F 6 . ? 48.169 48.477 16.446 1.00 16.86 ? 2340 HOH A O 1 HETATM 8815 O O . HOH F 6 . ? 11.491 46.931 17.829 1.00 24.07 ? 2341 HOH A O 1 HETATM 8816 O O . HOH F 6 . ? 16.519 67.968 -19.816 1.00 20.38 ? 2342 HOH A O 1 HETATM 8817 O O . HOH F 6 . ? 5.056 52.900 -5.948 1.00 30.91 ? 2343 HOH A O 1 HETATM 8818 O O . HOH F 6 . ? 56.518 91.113 -25.799 1.00 22.72 ? 2344 HOH A O 1 HETATM 8819 O O . HOH F 6 . ? 39.214 83.278 -27.427 1.00 21.90 ? 2345 HOH A O 1 HETATM 8820 O O . HOH F 6 . ? 60.942 56.803 15.962 1.00 29.00 ? 2346 HOH A O 1 HETATM 8821 O O . HOH F 6 . ? 13.408 51.502 21.720 1.00 19.43 ? 2347 HOH A O 1 HETATM 8822 O O . HOH F 6 . ? 43.501 93.969 -37.907 1.00 21.84 ? 2348 HOH A O 1 HETATM 8823 O O . HOH F 6 . ? 28.258 35.370 -6.774 1.00 21.42 ? 2349 HOH A O 1 HETATM 8824 O O . HOH F 6 . ? 80.602 64.224 -21.553 1.00 23.40 ? 2350 HOH A O 1 HETATM 8825 O O . HOH F 6 . ? 51.590 45.154 9.825 1.00 28.87 ? 2351 HOH A O 1 HETATM 8826 O O . HOH F 6 . ? 21.501 46.920 -17.541 1.00 27.58 ? 2352 HOH A O 1 HETATM 8827 O O . HOH F 6 . ? 47.561 71.952 -20.373 1.00 23.50 ? 2353 HOH A O 1 HETATM 8828 O O . HOH F 6 . ? 21.572 86.030 -30.857 1.00 33.05 ? 2354 HOH A O 1 HETATM 8829 O O . HOH F 6 . ? 33.141 67.061 21.414 1.00 20.58 ? 2355 HOH A O 1 HETATM 8830 O O . HOH F 6 . ? 14.661 62.048 -14.537 1.00 20.76 ? 2356 HOH A O 1 HETATM 8831 O O . HOH F 6 . ? 50.561 73.809 -25.400 1.00 23.00 ? 2357 HOH A O 1 HETATM 8832 O O . HOH F 6 . ? 42.062 79.466 -23.478 1.00 25.57 ? 2358 HOH A O 1 HETATM 8833 O O . HOH F 6 . ? 39.968 45.404 25.535 1.00 27.14 ? 2359 HOH A O 1 HETATM 8834 O O . HOH F 6 . ? 51.020 76.566 14.510 1.00 21.97 ? 2360 HOH A O 1 HETATM 8835 O O . HOH F 6 . ? 38.651 45.177 -33.788 1.00 22.92 ? 2361 HOH A O 1 HETATM 8836 O O . HOH F 6 . ? 61.444 54.391 -29.023 1.00 23.30 ? 2362 HOH A O 1 HETATM 8837 O O . HOH F 6 . ? 53.840 46.694 23.391 1.00 30.69 ? 2363 HOH A O 1 HETATM 8838 O O . HOH F 6 . ? 57.197 43.179 -20.012 1.00 23.29 ? 2364 HOH A O 1 HETATM 8839 O O . HOH F 6 . ? 67.842 54.863 -18.305 1.00 23.90 ? 2365 HOH A O 1 HETATM 8840 O O . HOH F 6 . ? 42.561 80.180 -31.779 1.00 30.45 ? 2366 HOH A O 1 HETATM 8841 O O . HOH F 6 . ? 29.190 62.338 -39.845 1.00 24.62 ? 2367 HOH A O 1 HETATM 8842 O O . HOH F 6 . ? 27.105 61.306 10.424 1.00 24.84 ? 2368 HOH A O 1 HETATM 8843 O O . HOH F 6 . ? 45.801 45.204 23.187 1.00 28.66 ? 2369 HOH A O 1 HETATM 8844 O O . HOH F 6 . ? 34.903 51.249 35.972 1.00 34.00 ? 2370 HOH A O 1 HETATM 8845 O O . HOH F 6 . ? 57.808 62.548 7.871 1.00 27.77 ? 2371 HOH A O 1 HETATM 8846 O O . HOH F 6 . ? 25.290 33.527 13.399 1.00 28.62 ? 2372 HOH A O 1 HETATM 8847 O O . HOH F 6 . ? 27.234 59.527 8.540 1.00 18.07 ? 2373 HOH A O 1 HETATM 8848 O O . HOH F 6 . ? 42.887 94.548 -30.436 1.00 44.39 ? 2374 HOH A O 1 HETATM 8849 O O . HOH F 6 . ? 14.058 58.011 -1.382 1.00 20.67 ? 2375 HOH A O 1 HETATM 8850 O O . HOH F 6 . ? 49.347 76.409 5.512 1.00 34.34 ? 2376 HOH A O 1 HETATM 8851 O O . HOH F 6 . ? 27.703 67.853 28.603 1.00 24.90 ? 2377 HOH A O 1 HETATM 8852 O O . HOH F 6 . ? 41.961 39.280 16.607 1.00 29.66 ? 2378 HOH A O 1 HETATM 8853 O O . HOH F 6 . ? 59.070 46.484 -1.418 1.00 21.64 ? 2379 HOH A O 1 HETATM 8854 O O . HOH F 6 . ? 73.438 76.956 -18.355 1.00 29.11 ? 2380 HOH A O 1 HETATM 8855 O O . HOH F 6 . ? 19.690 39.266 17.544 1.00 19.34 ? 2381 HOH A O 1 HETATM 8856 O O . HOH F 6 . ? 39.776 58.981 -18.087 1.00 21.50 ? 2382 HOH A O 1 HETATM 8857 O O . HOH F 6 . ? 28.182 47.150 -31.669 1.00 28.38 ? 2383 HOH A O 1 HETATM 8858 O O . HOH F 6 . ? 68.765 47.008 -16.756 1.00 30.08 ? 2384 HOH A O 1 HETATM 8859 O O . HOH F 6 . ? 66.670 62.598 -13.115 1.00 16.09 ? 2385 HOH A O 1 HETATM 8860 O O . HOH F 6 . ? 40.184 39.487 9.133 1.00 25.36 ? 2386 HOH A O 1 HETATM 8861 O O . HOH F 6 . ? 21.067 47.494 39.085 1.00 19.59 ? 2387 HOH A O 1 HETATM 8862 O O . HOH F 6 . ? 42.345 74.902 -41.557 1.00 25.66 ? 2388 HOH A O 1 HETATM 8863 O O . HOH F 6 . ? 14.558 55.235 27.225 1.00 33.32 ? 2389 HOH A O 1 HETATM 8864 O O . HOH F 6 . ? 28.706 59.859 -39.259 1.00 31.13 ? 2390 HOH A O 1 HETATM 8865 O O . HOH F 6 . ? 39.017 43.063 22.811 1.00 25.43 ? 2391 HOH A O 1 HETATM 8866 O O . HOH F 6 . ? 16.606 53.008 -22.544 1.00 28.80 ? 2392 HOH A O 1 HETATM 8867 O O . HOH F 6 . ? 27.215 35.035 29.524 1.00 25.28 ? 2393 HOH A O 1 HETATM 8868 O O . HOH F 6 . ? 17.358 80.827 -7.513 1.00 23.48 ? 2394 HOH A O 1 HETATM 8869 O O . HOH F 6 . ? 48.228 41.853 3.681 1.00 19.87 ? 2395 HOH A O 1 HETATM 8870 O O . HOH F 6 . ? 73.435 51.362 -11.436 1.00 34.35 ? 2396 HOH A O 1 HETATM 8871 O O . HOH F 6 . ? 58.899 53.799 -22.285 1.00 20.33 ? 2397 HOH A O 1 HETATM 8872 O O . HOH F 6 . ? 47.649 79.688 -18.474 1.00 24.30 ? 2398 HOH A O 1 HETATM 8873 O O . HOH F 6 . ? 40.854 96.645 -37.537 1.00 23.46 ? 2399 HOH A O 1 HETATM 8874 O O . HOH F 6 . ? 61.199 63.650 15.310 1.00 21.91 ? 2400 HOH A O 1 HETATM 8875 O O . HOH F 6 . ? 59.475 37.754 -15.327 1.00 24.88 ? 2401 HOH A O 1 HETATM 8876 O O . HOH F 6 . ? 21.068 30.235 17.823 1.00 33.96 ? 2402 HOH A O 1 HETATM 8877 O O . HOH F 6 . ? 46.173 97.057 -43.990 1.00 23.63 ? 2403 HOH A O 1 HETATM 8878 O O . HOH F 6 . ? 21.609 86.256 -19.259 1.00 27.38 ? 2404 HOH A O 1 HETATM 8879 O O . HOH F 6 . ? 20.525 68.455 22.370 1.00 24.39 ? 2405 HOH A O 1 HETATM 8880 O O . HOH F 6 . ? 45.293 69.343 -17.373 1.00 23.01 ? 2406 HOH A O 1 HETATM 8881 O O . HOH F 6 . ? 16.695 70.653 6.183 1.00 34.46 ? 2407 HOH A O 1 HETATM 8882 O O . HOH F 6 . ? 51.272 52.762 -28.747 1.00 19.80 ? 2408 HOH A O 1 HETATM 8883 O O . HOH F 6 . ? 19.172 83.484 -25.862 1.00 29.78 ? 2409 HOH A O 1 HETATM 8884 O O . HOH F 6 . ? 40.242 86.101 -22.008 1.00 27.20 ? 2410 HOH A O 1 HETATM 8885 O O . HOH F 6 . ? 22.525 66.361 29.215 1.00 32.79 ? 2411 HOH A O 1 HETATM 8886 O O . HOH F 6 . ? 25.016 59.468 -36.221 1.00 32.22 ? 2412 HOH A O 1 HETATM 8887 O O . HOH F 6 . ? 58.585 34.811 -5.657 1.00 33.44 ? 2413 HOH A O 1 HETATM 8888 O O . HOH F 6 . ? 50.749 79.190 -15.702 1.00 25.40 ? 2414 HOH A O 1 HETATM 8889 O O . HOH F 6 . ? 56.582 92.887 -29.585 1.00 27.13 ? 2415 HOH A O 1 HETATM 8890 O O . HOH F 6 . ? 52.738 73.134 4.104 1.00 37.77 ? 2416 HOH A O 1 HETATM 8891 O O . HOH F 6 . ? 22.064 36.875 0.192 1.00 23.46 ? 2417 HOH A O 1 HETATM 8892 O O . HOH F 6 . ? 10.703 77.299 -5.147 1.00 32.34 ? 2418 HOH A O 1 HETATM 8893 O O . HOH F 6 . ? 72.966 64.051 -21.028 1.00 24.81 ? 2419 HOH A O 1 HETATM 8894 O O . HOH F 6 . ? 79.972 74.026 -17.836 1.00 28.59 ? 2420 HOH A O 1 HETATM 8895 O O . HOH F 6 . ? 67.049 74.533 -4.410 1.00 28.43 ? 2421 HOH A O 1 HETATM 8896 O O . HOH F 6 . ? 48.256 64.474 -28.536 1.00 21.08 ? 2422 HOH A O 1 HETATM 8897 O O . HOH F 6 . ? 42.602 39.466 -1.516 1.00 27.15 ? 2423 HOH A O 1 HETATM 8898 O O . HOH F 6 . ? 63.363 67.842 -31.770 1.00 35.13 ? 2424 HOH A O 1 HETATM 8899 O O . HOH F 6 . ? 24.388 42.069 -14.654 1.00 23.79 ? 2425 HOH A O 1 HETATM 8900 O O . HOH F 6 . ? 27.618 50.993 13.355 1.00 16.54 ? 2426 HOH A O 1 HETATM 8901 O O . HOH F 6 . ? 38.812 83.715 -39.889 1.00 25.58 ? 2427 HOH A O 1 HETATM 8902 O O . HOH F 6 . ? 76.904 74.147 -26.797 1.00 29.70 ? 2428 HOH A O 1 HETATM 8903 O O . HOH F 6 . ? 28.857 72.519 22.519 1.00 26.21 ? 2429 HOH A O 1 HETATM 8904 O O . HOH F 6 . ? 20.921 55.182 -35.887 1.00 32.75 ? 2430 HOH A O 1 HETATM 8905 O O . HOH F 6 . ? 23.984 57.368 38.795 1.00 30.86 ? 2431 HOH A O 1 HETATM 8906 O O . HOH F 6 . ? 23.527 82.627 -40.816 1.00 21.87 ? 2432 HOH A O 1 HETATM 8907 O O . HOH F 6 . ? 17.197 67.248 -26.176 1.00 32.47 ? 2433 HOH A O 1 HETATM 8908 O O . HOH F 6 . ? 66.506 84.617 -22.407 1.00 34.38 ? 2434 HOH A O 1 HETATM 8909 O O . HOH F 6 . ? 20.716 68.106 8.444 1.00 19.45 ? 2435 HOH A O 1 HETATM 8910 O O . HOH F 6 . ? 61.894 63.947 -30.864 1.00 35.69 ? 2436 HOH A O 1 HETATM 8911 O O . HOH F 6 . ? 9.791 59.890 6.382 1.00 36.01 ? 2437 HOH A O 1 HETATM 8912 O O . HOH F 6 . ? 31.681 85.900 -19.954 1.00 22.78 ? 2438 HOH A O 1 HETATM 8913 O O . HOH F 6 . ? 28.224 88.073 -41.770 1.00 28.87 ? 2439 HOH A O 1 HETATM 8914 O O . HOH F 6 . ? 44.878 82.707 -30.581 1.00 21.73 ? 2440 HOH A O 1 HETATM 8915 O O . HOH F 6 . ? 59.657 67.072 -34.669 1.00 26.83 ? 2441 HOH A O 1 HETATM 8916 O O . HOH F 6 . ? 70.525 56.506 -12.501 1.00 32.88 ? 2442 HOH A O 1 HETATM 8917 O O . HOH F 6 . ? 46.267 46.278 16.267 1.00 31.97 ? 2443 HOH A O 1 HETATM 8918 O O . HOH F 6 . ? 45.986 82.806 -25.342 1.00 31.60 ? 2444 HOH A O 1 HETATM 8919 O O . HOH F 6 . ? 56.994 87.741 -20.079 1.00 28.24 ? 2445 HOH A O 1 HETATM 8920 O O . HOH F 6 . ? 73.832 74.245 -5.811 1.00 23.55 ? 2446 HOH A O 1 HETATM 8921 O O . HOH F 6 . ? 19.900 43.247 33.961 1.00 25.45 ? 2447 HOH A O 1 HETATM 8922 O O . HOH F 6 . ? 79.438 51.229 -0.645 1.00 22.68 ? 2448 HOH A O 1 HETATM 8923 O O . HOH F 6 . ? 66.444 45.453 -3.350 1.00 28.53 ? 2449 HOH A O 1 HETATM 8924 O O . HOH F 6 . ? 48.629 78.132 -9.758 1.00 26.10 ? 2450 HOH A O 1 HETATM 8925 O O . HOH F 6 . ? 30.079 34.159 -1.558 1.00 25.91 ? 2451 HOH A O 1 HETATM 8926 O O . HOH F 6 . ? 16.227 75.270 -24.136 1.00 36.03 ? 2452 HOH A O 1 HETATM 8927 O O . HOH F 6 . ? 22.407 31.196 29.459 1.00 30.84 ? 2453 HOH A O 1 HETATM 8928 O O . HOH F 6 . ? 33.463 84.487 -18.359 1.00 16.72 ? 2454 HOH A O 1 HETATM 8929 O O . HOH F 6 . ? 41.408 94.907 -39.620 1.00 25.92 ? 2455 HOH A O 1 HETATM 8930 O O . HOH F 6 . ? 44.478 83.852 -27.907 1.00 25.49 ? 2456 HOH A O 1 HETATM 8931 O O . HOH F 6 . ? 30.985 57.368 4.653 1.00 13.94 ? 2457 HOH A O 1 HETATM 8932 O O . HOH F 6 . ? 66.151 66.192 -0.546 1.00 23.47 ? 2458 HOH A O 1 HETATM 8933 O O . HOH F 6 . ? 46.420 68.783 26.468 1.00 31.51 ? 2459 HOH A O 1 HETATM 8934 O O . HOH F 6 . ? 70.376 61.856 -20.437 1.00 28.54 ? 2460 HOH A O 1 HETATM 8935 O O . HOH F 6 . ? 23.871 91.072 -26.175 1.00 34.82 ? 2461 HOH A O 1 HETATM 8936 O O . HOH F 6 . ? 25.202 71.299 22.663 1.00 35.27 ? 2462 HOH A O 1 HETATM 8937 O O . HOH F 6 . ? 14.064 69.449 26.907 1.00 22.72 ? 2463 HOH A O 1 HETATM 8938 O O . HOH F 6 . ? 62.400 80.798 -18.989 1.00 24.05 ? 2464 HOH A O 1 HETATM 8939 O O . HOH F 6 . ? 27.700 47.588 45.871 1.00 37.20 ? 2465 HOH A O 1 HETATM 8940 O O . HOH F 6 . ? 24.891 34.398 0.310 1.00 41.26 ? 2466 HOH A O 1 HETATM 8941 O O . HOH F 6 . ? 57.774 67.849 13.995 1.00 52.15 ? 2467 HOH A O 1 HETATM 8942 O O . HOH F 6 . ? 8.018 48.225 11.931 1.00 24.32 ? 2468 HOH A O 1 HETATM 8943 O O . HOH F 6 . ? 71.590 59.852 0.983 1.00 35.85 ? 2469 HOH A O 1 HETATM 8944 O O . HOH F 6 . ? 67.903 88.188 -23.569 1.00 25.43 ? 2470 HOH A O 1 HETATM 8945 O O . HOH F 6 . ? 12.419 75.129 -13.540 1.00 30.56 ? 2471 HOH A O 1 HETATM 8946 O O . HOH F 6 . ? 27.678 52.085 42.591 1.00 29.94 ? 2472 HOH A O 1 HETATM 8947 O O . HOH F 6 . ? 22.104 62.895 33.791 1.00 32.64 ? 2473 HOH A O 1 HETATM 8948 O O . HOH F 6 . ? 34.545 87.227 -10.612 1.00 32.54 ? 2474 HOH A O 1 HETATM 8949 O O . HOH F 6 . ? 30.194 36.570 29.109 1.00 26.06 ? 2475 HOH A O 1 HETATM 8950 O O . HOH F 6 . ? 8.486 49.782 5.728 1.00 42.76 ? 2476 HOH A O 1 HETATM 8951 O O . HOH F 6 . ? 42.054 67.460 29.351 1.00 27.40 ? 2477 HOH A O 1 HETATM 8952 O O . HOH F 6 . ? 72.666 75.917 -27.354 1.00 34.61 ? 2478 HOH A O 1 HETATM 8953 O O . HOH F 6 . ? 8.797 44.535 12.804 1.00 31.20 ? 2479 HOH A O 1 HETATM 8954 O O . HOH F 6 . ? 41.542 44.727 -24.434 1.00 22.44 ? 2480 HOH A O 1 HETATM 8955 O O . HOH F 6 . ? 39.822 67.003 31.390 1.00 25.00 ? 2481 HOH A O 1 HETATM 8956 O O . HOH F 6 . ? 53.494 52.656 26.296 1.00 21.15 ? 2482 HOH A O 1 HETATM 8957 O O . HOH F 6 . ? 26.358 44.404 -27.285 1.00 29.81 ? 2483 HOH A O 1 HETATM 8958 O O . HOH F 6 . ? 19.811 52.552 -27.180 1.00 27.64 ? 2484 HOH A O 1 HETATM 8959 O O . HOH F 6 . ? 70.627 95.475 -35.112 1.00 45.57 ? 2485 HOH A O 1 HETATM 8960 O O . HOH F 6 . ? 48.298 64.935 -25.860 1.00 23.41 ? 2486 HOH A O 1 HETATM 8961 O O . HOH F 6 . ? 44.499 64.432 -35.553 1.00 51.97 ? 2487 HOH A O 1 HETATM 8962 O O . HOH F 6 . ? 17.601 53.401 35.213 1.00 30.16 ? 2488 HOH A O 1 HETATM 8963 O O . HOH F 6 . ? 83.772 70.230 -20.245 1.00 26.30 ? 2489 HOH A O 1 HETATM 8964 O O . HOH F 6 . ? 44.034 79.918 -42.604 1.00 29.60 ? 2490 HOH A O 1 HETATM 8965 O O . HOH F 6 . ? 22.652 62.618 16.172 1.00 24.46 ? 2491 HOH A O 1 HETATM 8966 O O . HOH F 6 . ? 45.868 79.358 -7.914 1.00 23.82 ? 2492 HOH A O 1 HETATM 8967 O O . HOH F 6 . ? 38.777 42.296 -22.190 1.00 26.65 ? 2493 HOH A O 1 HETATM 8968 O O . HOH F 6 . ? 36.950 29.274 13.168 1.00 32.48 ? 2494 HOH A O 1 HETATM 8969 O O . HOH F 6 . ? 20.453 65.553 27.341 1.00 25.68 ? 2495 HOH A O 1 HETATM 8970 O O . HOH F 6 . ? 7.031 59.715 2.244 1.00 44.13 ? 2496 HOH A O 1 HETATM 8971 O O . HOH F 6 . ? 61.357 77.596 -13.059 1.00 21.38 ? 2497 HOH A O 1 HETATM 8972 O O . HOH F 6 . ? 28.148 49.376 38.523 1.00 27.12 ? 2498 HOH A O 1 HETATM 8973 O O . HOH F 6 . ? 19.543 67.411 -2.809 1.00 27.80 ? 2499 HOH A O 1 HETATM 8974 O O . HOH F 6 . ? 43.685 41.915 -7.575 1.00 24.22 ? 2500 HOH A O 1 HETATM 8975 O O . HOH F 6 . ? 48.707 54.994 -22.828 1.00 19.20 ? 2501 HOH A O 1 HETATM 8976 O O . HOH F 6 . ? 35.854 39.059 -16.220 1.00 27.46 ? 2502 HOH A O 1 HETATM 8977 O O . HOH F 6 . ? 58.682 51.200 22.368 1.00 19.12 ? 2503 HOH A O 1 HETATM 8978 O O . HOH F 6 . ? 46.667 80.363 -42.742 1.00 27.96 ? 2504 HOH A O 1 HETATM 8979 O O . HOH F 6 . ? 71.933 84.693 -20.180 1.00 27.92 ? 2505 HOH A O 1 HETATM 8980 O O . HOH F 6 . ? 61.426 67.809 -36.444 1.00 32.58 ? 2506 HOH A O 1 HETATM 8981 O O . HOH F 6 . ? 58.650 34.925 -12.440 1.00 38.16 ? 2507 HOH A O 1 HETATM 8982 O O . HOH F 6 . ? 21.172 79.580 -23.601 1.00 23.60 ? 2508 HOH A O 1 HETATM 8983 O O . HOH F 6 . ? 51.379 71.481 -20.231 1.00 19.79 ? 2509 HOH A O 1 HETATM 8984 O O . HOH F 6 . ? 32.218 85.337 -8.603 1.00 20.73 ? 2510 HOH A O 1 HETATM 8985 O O . HOH F 6 . ? 21.821 29.141 28.099 1.00 35.55 ? 2511 HOH A O 1 HETATM 8986 O O . HOH F 6 . ? 31.558 57.418 37.489 1.00 27.57 ? 2512 HOH A O 1 HETATM 8987 O O . HOH F 6 . ? 17.573 81.351 -17.185 1.00 48.09 ? 2513 HOH A O 1 HETATM 8988 O O . HOH F 6 . ? 22.121 80.320 -36.195 1.00 24.39 ? 2514 HOH A O 1 HETATM 8989 O O . HOH F 6 . ? 25.420 73.939 8.740 1.00 27.85 ? 2515 HOH A O 1 HETATM 8990 O O . HOH F 6 . ? 21.601 79.922 5.319 1.00 28.03 ? 2516 HOH A O 1 HETATM 8991 O O . HOH F 6 . ? 40.026 38.928 -3.479 1.00 21.73 ? 2517 HOH A O 1 HETATM 8992 O O . HOH F 6 . ? 36.817 35.239 -15.929 1.00 29.10 ? 2518 HOH A O 1 HETATM 8993 O O . HOH F 6 . ? 34.837 45.772 33.367 1.00 18.60 ? 2519 HOH A O 1 HETATM 8994 O O . HOH F 6 . ? 46.492 74.382 22.459 1.00 31.58 ? 2520 HOH A O 1 HETATM 8995 O O . HOH F 6 . ? 60.600 91.994 -28.645 1.00 28.98 ? 2521 HOH A O 1 HETATM 8996 O O . HOH F 6 . ? 37.745 62.323 35.589 1.00 35.37 ? 2522 HOH A O 1 HETATM 8997 O O . HOH F 6 . ? 63.110 42.816 -20.955 1.00 25.92 ? 2523 HOH A O 1 HETATM 8998 O O . HOH F 6 . ? 30.537 34.880 -9.621 1.00 34.56 ? 2524 HOH A O 1 HETATM 8999 O O . HOH F 6 . ? 29.555 31.397 21.994 1.00 36.90 ? 2525 HOH A O 1 HETATM 9000 O O . HOH F 6 . ? 78.922 68.924 -12.180 1.00 29.84 ? 2526 HOH A O 1 HETATM 9001 O O . HOH F 6 . ? 31.308 69.371 -45.574 1.00 39.24 ? 2527 HOH A O 1 HETATM 9002 O O . HOH F 6 . ? 73.605 82.320 -21.265 1.00 27.08 ? 2528 HOH A O 1 HETATM 9003 O O . HOH F 6 . ? 20.596 37.961 12.114 1.00 28.86 ? 2529 HOH A O 1 HETATM 9004 O O . HOH F 6 . ? 35.166 95.004 -32.353 1.00 29.89 ? 2530 HOH A O 1 HETATM 9005 O O . HOH F 6 . ? 17.458 41.748 9.280 1.00 26.78 ? 2531 HOH A O 1 HETATM 9006 O O . HOH F 6 . ? 20.613 80.348 -33.650 1.00 44.91 ? 2532 HOH A O 1 HETATM 9007 O O . HOH F 6 . ? 49.485 91.967 -24.618 1.00 33.54 ? 2533 HOH A O 1 HETATM 9008 O O . HOH F 6 . ? 43.917 45.017 19.312 1.00 35.90 ? 2534 HOH A O 1 HETATM 9009 O O . HOH F 6 . ? 21.214 35.726 -5.000 1.00 36.20 ? 2535 HOH A O 1 HETATM 9010 O O . HOH F 6 . ? 46.982 53.975 -21.522 1.00 27.07 ? 2536 HOH A O 1 HETATM 9011 O O . HOH F 6 . ? 71.562 63.108 -27.231 1.00 47.05 ? 2537 HOH A O 1 HETATM 9012 O O . HOH F 6 . ? 19.861 35.611 25.550 1.00 28.32 ? 2538 HOH A O 1 HETATM 9013 O O . HOH F 6 . ? 59.411 86.877 -45.961 1.00 40.80 ? 2539 HOH A O 1 HETATM 9014 O O . HOH F 6 . ? 28.865 69.848 -39.632 1.00 22.44 ? 2540 HOH A O 1 HETATM 9015 O O . HOH F 6 . ? 45.382 83.598 -43.190 1.00 36.53 ? 2541 HOH A O 1 HETATM 9016 O O . HOH F 6 . ? 29.667 81.445 -43.209 1.00 41.28 ? 2542 HOH A O 1 HETATM 9017 O O . HOH F 6 . ? 28.194 90.922 -42.744 1.00 28.83 ? 2543 HOH A O 1 HETATM 9018 O O . HOH F 6 . ? 21.045 41.775 35.280 1.00 28.74 ? 2544 HOH A O 1 HETATM 9019 O O . HOH F 6 . ? 62.469 85.559 -23.060 1.00 30.21 ? 2545 HOH A O 1 HETATM 9020 O O . HOH F 6 . ? 31.162 68.679 14.209 1.00 25.80 ? 2546 HOH A O 1 HETATM 9021 O O . HOH F 6 . ? 27.510 67.364 33.829 1.00 38.88 ? 2547 HOH A O 1 HETATM 9022 O O . HOH F 6 . ? 15.063 63.762 -25.829 1.00 23.34 ? 2548 HOH A O 1 HETATM 9023 O O . HOH F 6 . ? 29.590 72.270 12.362 1.00 31.21 ? 2549 HOH A O 1 HETATM 9024 O O . HOH F 6 . ? 60.782 93.112 -38.555 1.00 47.99 ? 2550 HOH A O 1 HETATM 9025 O O . HOH F 6 . ? 59.155 62.406 25.849 1.00 23.13 ? 2551 HOH A O 1 HETATM 9026 O O . HOH F 6 . ? 51.464 79.437 -1.785 1.00 24.61 ? 2552 HOH A O 1 HETATM 9027 O O . HOH F 6 . ? 59.739 91.259 -35.537 1.00 25.52 ? 2553 HOH A O 1 HETATM 9028 O O . HOH F 6 . ? 24.058 60.818 36.139 1.00 31.79 ? 2554 HOH A O 1 HETATM 9029 O O . HOH F 6 . ? 55.448 80.664 -19.425 1.00 24.37 ? 2555 HOH A O 1 HETATM 9030 O O . HOH F 6 . ? 16.796 74.471 -28.783 1.00 49.29 ? 2556 HOH A O 1 HETATM 9031 O O . HOH F 6 . ? 40.987 40.756 -21.603 1.00 24.59 ? 2557 HOH A O 1 HETATM 9032 O O . HOH F 6 . ? 40.080 35.483 11.340 1.00 24.13 ? 2558 HOH A O 1 HETATM 9033 O O . HOH F 6 . ? 18.998 80.760 -11.740 1.00 31.30 ? 2559 HOH A O 1 HETATM 9034 O O . HOH F 6 . ? 73.298 43.755 -12.329 1.00 46.39 ? 2560 HOH A O 1 HETATM 9035 O O . HOH F 6 . ? 12.883 74.426 -19.089 1.00 38.13 ? 2561 HOH A O 1 HETATM 9036 O O . HOH F 6 . ? 57.293 75.617 -3.016 1.00 25.60 ? 2562 HOH A O 1 HETATM 9037 O O . HOH F 6 . ? 50.951 77.161 2.137 1.00 38.38 ? 2563 HOH A O 1 HETATM 9038 O O . HOH F 6 . ? 23.224 36.972 13.383 1.00 28.08 ? 2564 HOH A O 1 HETATM 9039 O O . HOH F 6 . ? 29.632 88.851 -26.277 1.00 13.04 ? 2565 HOH A O 1 HETATM 9040 O O . HOH F 6 . ? 37.203 33.622 6.060 1.00 48.19 ? 2566 HOH A O 1 HETATM 9041 O O . HOH F 6 . ? 71.897 62.690 -18.078 1.00 32.18 ? 2567 HOH A O 1 HETATM 9042 O O . HOH F 6 . ? 34.142 70.340 -44.814 1.00 41.15 ? 2568 HOH A O 1 HETATM 9043 O O . HOH F 6 . ? 64.663 77.327 0.375 1.00 38.62 ? 2569 HOH A O 1 HETATM 9044 O O . HOH F 6 . ? 20.954 54.812 47.322 1.00 45.36 ? 2570 HOH A O 1 HETATM 9045 O O . HOH F 6 . ? 14.517 50.726 1.026 1.00 29.21 ? 2571 HOH A O 1 HETATM 9046 O O . HOH F 6 . ? 55.631 38.606 1.011 1.00 48.04 ? 2572 HOH A O 1 HETATM 9047 O O . HOH F 6 . ? 67.019 81.458 -11.338 1.00 30.92 ? 2573 HOH A O 1 HETATM 9048 O O . HOH F 6 . ? 43.680 56.706 33.823 1.00 24.92 ? 2574 HOH A O 1 HETATM 9049 O O . HOH F 6 . ? 56.459 50.028 -30.217 1.00 39.48 ? 2575 HOH A O 1 HETATM 9050 O O . HOH F 6 . ? 63.452 57.677 25.864 1.00 38.88 ? 2576 HOH A O 1 HETATM 9051 O O . HOH F 6 . ? 62.150 48.242 -21.095 1.00 36.66 ? 2577 HOH A O 1 HETATM 9052 O O . HOH F 6 . ? 26.788 91.845 -27.704 1.00 28.26 ? 2578 HOH A O 1 HETATM 9053 O O . HOH F 6 . ? 13.664 70.248 -9.669 1.00 28.28 ? 2579 HOH A O 1 HETATM 9054 O O . HOH F 6 . ? 60.867 79.004 -41.668 1.00 28.47 ? 2580 HOH A O 1 HETATM 9055 O O . HOH F 6 . ? 36.564 62.775 -38.348 1.00 31.18 ? 2581 HOH A O 1 HETATM 9056 O O . HOH F 6 . ? 37.799 80.584 -0.688 1.00 19.29 ? 2582 HOH A O 1 HETATM 9057 O O . HOH F 6 . ? 47.471 53.546 35.898 1.00 39.20 ? 2583 HOH A O 1 HETATM 9058 O O . HOH F 6 . ? 48.663 97.922 -33.925 1.00 34.06 ? 2584 HOH A O 1 HETATM 9059 O O . HOH F 6 . ? 63.169 74.681 -46.177 1.00 36.35 ? 2585 HOH A O 1 HETATM 9060 O O . HOH F 6 . ? 41.182 48.019 -29.144 1.00 40.87 ? 2586 HOH A O 1 HETATM 9061 O O . HOH F 6 . ? 63.656 52.004 -0.476 1.00 29.21 ? 2587 HOH A O 1 HETATM 9062 O O . HOH F 6 . ? 22.931 49.011 -36.362 1.00 40.34 ? 2588 HOH A O 1 HETATM 9063 O O . HOH F 6 . ? 18.639 71.058 -29.925 1.00 43.32 ? 2589 HOH A O 1 HETATM 9064 O O . HOH F 6 . ? 27.498 50.005 23.254 1.00 33.08 ? 2590 HOH A O 1 HETATM 9065 O O . HOH F 6 . ? 60.066 52.948 -30.621 1.00 30.14 ? 2591 HOH A O 1 HETATM 9066 O O . HOH F 6 . ? 34.302 47.978 36.295 1.00 35.03 ? 2592 HOH A O 1 HETATM 9067 O O . HOH F 6 . ? 27.534 82.469 3.220 1.00 33.04 ? 2593 HOH A O 1 HETATM 9068 O O . HOH F 6 . ? 53.445 70.949 -17.082 1.00 28.29 ? 2594 HOH A O 1 HETATM 9069 O O . HOH F 6 . ? 28.557 44.334 -29.678 1.00 33.12 ? 2595 HOH A O 1 HETATM 9070 O O . HOH F 6 . ? 49.543 49.155 -38.176 1.00 51.26 ? 2596 HOH A O 1 HETATM 9071 O O . HOH F 6 . ? 35.752 77.534 -43.160 1.00 32.63 ? 2597 HOH A O 1 HETATM 9072 O O . HOH F 6 . ? 65.516 78.826 -5.894 1.00 27.42 ? 2598 HOH A O 1 HETATM 9073 O O . HOH F 6 . ? 49.490 50.794 32.629 1.00 28.42 ? 2599 HOH A O 1 HETATM 9074 O O . HOH F 6 . ? 17.581 45.738 -14.074 1.00 30.44 ? 2600 HOH A O 1 HETATM 9075 O O . HOH F 6 . ? 28.458 55.455 40.059 1.00 28.04 ? 2601 HOH A O 1 HETATM 9076 O O . HOH F 6 . ? 51.021 59.978 -8.968 1.00 12.12 ? 2602 HOH A O 1 HETATM 9077 O O . HOH F 6 . ? 43.927 63.080 -28.716 1.00 10.73 ? 2603 HOH A O 1 HETATM 9078 O O . HOH F 6 . ? 38.246 81.862 -31.453 1.00 13.59 ? 2604 HOH A O 1 HETATM 9079 O O . HOH F 6 . ? 32.412 39.239 -4.932 1.00 11.65 ? 2605 HOH A O 1 HETATM 9080 O O . HOH F 6 . ? 60.589 61.018 -18.205 1.00 10.46 ? 2606 HOH A O 1 HETATM 9081 O O . HOH F 6 . ? 63.372 58.677 -1.459 1.00 16.20 ? 2607 HOH A O 1 HETATM 9082 O O . HOH F 6 . ? 60.868 60.922 -3.653 1.00 13.11 ? 2608 HOH A O 1 HETATM 9083 O O . HOH F 6 . ? 46.862 74.584 7.766 1.00 12.05 ? 2609 HOH A O 1 HETATM 9084 O O . HOH F 6 . ? 55.208 57.675 -0.497 1.00 16.53 ? 2610 HOH A O 1 HETATM 9085 O O . HOH F 6 . ? 30.377 75.047 -29.343 1.00 13.32 ? 2611 HOH A O 1 HETATM 9086 O O . HOH F 6 . ? 59.106 56.839 -1.464 1.00 12.42 ? 2612 HOH A O 1 HETATM 9087 O O . HOH F 6 . ? 58.934 52.707 -0.150 1.00 13.34 ? 2613 HOH A O 1 HETATM 9088 O O . HOH F 6 . ? 63.280 61.169 -4.917 1.00 14.52 ? 2614 HOH A O 1 HETATM 9089 O O . HOH F 6 . ? 27.974 48.687 12.126 1.00 14.28 ? 2615 HOH A O 1 HETATM 9090 O O . HOH F 6 . ? 66.768 56.280 -20.322 1.00 17.88 ? 2616 HOH A O 1 HETATM 9091 O O . HOH F 6 . ? 19.997 46.809 -14.377 1.00 19.24 ? 2617 HOH A O 1 HETATM 9092 O O . HOH F 6 . ? 38.783 69.300 -38.243 1.00 17.11 ? 2618 HOH A O 1 HETATM 9093 O O . HOH F 6 . ? 33.639 60.269 23.247 1.00 13.42 ? 2619 HOH A O 1 HETATM 9094 O O . HOH F 6 . ? 39.760 55.788 3.029 1.00 12.95 ? 2620 HOH A O 1 HETATM 9095 O O . HOH F 6 . ? 24.662 61.466 9.232 1.00 14.85 ? 2621 HOH A O 1 HETATM 9096 O O . HOH F 6 . ? 16.741 57.122 12.988 1.00 14.15 ? 2622 HOH A O 1 HETATM 9097 O O . HOH F 6 . ? 39.447 69.224 -35.500 1.00 15.96 ? 2623 HOH A O 1 HETATM 9098 O O . HOH F 6 . ? 50.040 67.592 4.238 1.00 17.19 ? 2624 HOH A O 1 HETATM 9099 O O . HOH F 6 . ? 27.734 53.359 20.188 1.00 15.80 ? 2625 HOH A O 1 HETATM 9100 O O . HOH F 6 . ? 29.960 83.164 2.492 1.00 20.65 ? 2626 HOH A O 1 HETATM 9101 O O . HOH F 6 . ? 28.149 91.008 -25.408 1.00 19.72 ? 2627 HOH A O 1 HETATM 9102 O O . HOH F 6 . ? 46.276 77.782 9.514 1.00 20.28 ? 2628 HOH A O 1 HETATM 9103 O O . HOH F 6 . ? 12.544 49.512 17.729 1.00 21.50 ? 2629 HOH A O 1 HETATM 9104 O O . HOH F 6 . ? 81.502 68.631 -11.528 1.00 24.98 ? 2630 HOH A O 1 HETATM 9105 O O . HOH F 6 . ? 41.586 44.860 -6.904 1.00 13.11 ? 2631 HOH A O 1 HETATM 9106 O O . HOH F 6 . ? 45.622 67.917 -27.798 1.00 21.53 ? 2632 HOH A O 1 HETATM 9107 O O . HOH F 6 . ? 14.083 50.493 24.216 1.00 21.10 ? 2633 HOH A O 1 HETATM 9108 O O . HOH F 6 . ? 67.736 46.625 -1.408 1.00 23.78 ? 2634 HOH A O 1 HETATM 9109 O O . HOH F 6 . ? 9.051 50.513 7.952 1.00 28.93 ? 2635 HOH A O 1 HETATM 9110 O O . HOH F 6 . ? 48.662 40.973 -1.034 1.00 23.85 ? 2636 HOH A O 1 HETATM 9111 O O . HOH F 6 . ? 17.896 74.617 3.862 1.00 23.17 ? 2637 HOH A O 1 HETATM 9112 O O . HOH F 6 . ? 45.062 55.105 -18.215 1.00 24.70 ? 2638 HOH A O 1 HETATM 9113 O O . HOH F 6 . ? 83.650 66.470 -15.466 1.00 22.00 ? 2639 HOH A O 1 HETATM 9114 O O . HOH F 6 . ? 49.132 69.165 -36.958 1.00 25.95 ? 2640 HOH A O 1 HETATM 9115 O O . HOH F 6 . ? 51.715 70.188 -38.106 1.00 23.08 ? 2641 HOH A O 1 HETATM 9116 O O . HOH F 6 . ? 29.694 72.380 34.459 1.00 25.92 ? 2642 HOH A O 1 HETATM 9117 O O . HOH F 6 . ? 37.706 61.503 -32.578 1.00 22.31 ? 2643 HOH A O 1 HETATM 9118 O O . HOH F 6 . ? 57.409 48.972 21.425 1.00 21.34 ? 2644 HOH A O 1 HETATM 9119 O O . HOH F 6 . ? 43.117 59.610 -31.533 1.00 21.00 ? 2645 HOH A O 1 HETATM 9120 O O . HOH F 6 . ? 32.130 34.465 -3.253 1.00 21.02 ? 2646 HOH A O 1 HETATM 9121 O O . HOH F 6 . ? 37.173 59.102 -33.653 1.00 24.28 ? 2647 HOH A O 1 HETATM 9122 O O . HOH F 6 . ? 61.736 59.032 14.976 1.00 25.33 ? 2648 HOH A O 1 HETATM 9123 O O . HOH F 6 . ? 40.411 56.317 -19.260 1.00 27.29 ? 2649 HOH A O 1 HETATM 9124 O O . HOH F 6 . ? 61.956 76.460 -10.657 1.00 18.38 ? 2650 HOH A O 1 HETATM 9125 O O . HOH F 6 . ? 79.662 50.950 -11.496 1.00 44.32 ? 2651 HOH A O 1 HETATM 9126 O O . HOH F 6 . ? 37.720 51.642 -18.573 1.00 17.81 ? 2652 HOH A O 1 HETATM 9127 O O . HOH F 6 . ? 25.584 52.323 13.001 1.00 18.74 ? 2653 HOH A O 1 HETATM 9128 O O . HOH F 6 . ? 69.758 63.939 -28.800 1.00 26.50 ? 2654 HOH A O 1 HETATM 9129 O O . HOH F 6 . ? 73.169 66.625 -10.120 1.00 22.21 ? 2655 HOH A O 1 HETATM 9130 O O . HOH F 6 . ? 42.904 56.550 2.758 1.00 18.12 ? 2656 HOH A O 1 HETATM 9131 O O . HOH F 6 . ? 56.286 65.132 -36.283 1.00 20.32 ? 2657 HOH A O 1 HETATM 9132 O O . HOH F 6 . ? 17.889 66.074 28.004 1.00 24.25 ? 2658 HOH A O 1 HETATM 9133 O O . HOH F 6 . ? 11.742 63.670 -16.917 1.00 22.23 ? 2659 HOH A O 1 HETATM 9134 O O . HOH F 6 . ? 35.564 86.326 -18.034 1.00 26.59 ? 2660 HOH A O 1 HETATM 9135 O O . HOH F 6 . ? 9.906 60.401 -20.414 1.00 26.88 ? 2661 HOH A O 1 HETATM 9136 O O . HOH F 6 . ? 11.605 48.713 -2.486 1.00 30.11 ? 2662 HOH A O 1 HETATM 9137 O O . HOH F 6 . ? 40.027 52.873 36.393 1.00 28.54 ? 2663 HOH A O 1 HETATM 9138 O O . HOH F 6 . ? 49.996 47.467 28.986 1.00 20.64 ? 2664 HOH A O 1 HETATM 9139 O O . HOH F 6 . ? 24.133 34.421 15.511 1.00 27.51 ? 2665 HOH A O 1 HETATM 9140 O O . HOH F 6 . ? 59.627 50.955 24.836 1.00 26.00 ? 2666 HOH A O 1 HETATM 9141 O O . HOH F 6 . ? 38.150 83.436 -1.198 1.00 26.61 ? 2667 HOH A O 1 HETATM 9142 O O . HOH F 6 . ? 12.928 51.712 -12.197 1.00 26.85 ? 2668 HOH A O 1 HETATM 9143 O O . HOH F 6 . ? 48.349 50.936 35.193 1.00 29.09 ? 2669 HOH A O 1 HETATM 9144 O O . HOH F 6 . ? 48.186 41.633 -5.403 1.00 26.32 ? 2670 HOH A O 1 HETATM 9145 O O . HOH F 6 . ? 22.285 40.821 -11.279 1.00 22.03 ? 2671 HOH A O 1 HETATM 9146 O O . HOH F 6 . ? 16.234 36.430 16.395 1.00 30.41 ? 2672 HOH A O 1 HETATM 9147 O O . HOH F 6 . ? 22.449 68.253 20.504 1.00 24.57 ? 2673 HOH A O 1 HETATM 9148 O O . HOH F 6 . ? 40.970 85.290 -12.216 1.00 26.63 ? 2674 HOH A O 1 HETATM 9149 O O . HOH F 6 . ? 56.953 46.772 15.889 1.00 27.36 ? 2675 HOH A O 1 HETATM 9150 O O . HOH F 6 . ? 51.835 64.040 24.620 1.00 23.22 ? 2676 HOH A O 1 HETATM 9151 O O . HOH F 6 . ? 56.764 58.642 1.309 1.00 28.44 ? 2677 HOH A O 1 HETATM 9152 O O . HOH F 6 . ? 57.687 58.563 5.519 1.00 25.93 ? 2678 HOH A O 1 HETATM 9153 O O . HOH F 6 . ? 75.340 64.209 -16.396 1.00 29.94 ? 2679 HOH A O 1 HETATM 9154 O O . HOH F 6 . ? 14.698 70.633 -23.076 1.00 27.87 ? 2680 HOH A O 1 HETATM 9155 O O . HOH F 6 . ? 13.260 52.237 -15.050 1.00 28.78 ? 2681 HOH A O 1 HETATM 9156 O O . HOH F 6 . ? 23.280 86.953 -32.691 1.00 34.49 ? 2682 HOH A O 1 HETATM 9157 O O . HOH F 6 . ? 66.486 81.848 -14.304 1.00 27.58 ? 2683 HOH A O 1 HETATM 9158 O O . HOH F 6 . ? 47.466 61.517 -28.887 1.00 26.21 ? 2684 HOH A O 1 HETATM 9159 O O . HOH F 6 . ? 52.201 70.653 6.026 1.00 34.74 ? 2685 HOH A O 1 HETATM 9160 O O . HOH F 6 . ? 41.040 56.032 -33.316 1.00 26.34 ? 2686 HOH A O 1 HETATM 9161 O O . HOH F 6 . ? 39.902 39.846 20.057 1.00 31.43 ? 2687 HOH A O 1 HETATM 9162 O O . HOH F 6 . ? 44.350 55.683 36.173 1.00 36.73 ? 2688 HOH A O 1 HETATM 9163 O O . HOH F 6 . ? 13.811 62.535 14.629 1.00 28.97 ? 2689 HOH A O 1 HETATM 9164 O O . HOH F 6 . ? 40.111 39.799 -0.354 1.00 22.69 ? 2690 HOH A O 1 HETATM 9165 O O . HOH F 6 . ? 27.076 41.707 -27.616 1.00 33.54 ? 2691 HOH A O 1 HETATM 9166 O O . HOH F 6 . ? 19.888 41.661 -4.987 1.00 27.16 ? 2692 HOH A O 1 HETATM 9167 O O . HOH F 6 . ? 13.717 60.800 7.705 1.00 26.28 ? 2693 HOH A O 1 HETATM 9168 O O . HOH F 6 . ? 47.110 46.059 11.429 1.00 33.54 ? 2694 HOH A O 1 HETATM 9169 O O . HOH F 6 . ? 43.088 68.593 -30.103 1.00 30.08 ? 2695 HOH A O 1 HETATM 9170 O O . HOH F 6 . ? 47.864 69.982 -16.733 1.00 31.92 ? 2696 HOH A O 1 HETATM 9171 O O . HOH F 6 . ? 58.932 93.492 -27.329 1.00 36.23 ? 2697 HOH A O 1 HETATM 9172 O O . HOH F 6 . ? 31.490 79.227 -43.027 1.00 28.04 ? 2698 HOH A O 1 HETATM 9173 O O . HOH F 6 . ? 22.252 42.830 -13.257 1.00 25.52 ? 2699 HOH A O 1 HETATM 9174 O O . HOH F 6 . ? 52.794 92.141 -23.498 1.00 30.99 ? 2700 HOH A O 1 HETATM 9175 O O . HOH F 6 . ? 60.507 50.955 20.360 1.00 29.96 ? 2701 HOH A O 1 HETATM 9176 O O . HOH F 6 . ? 19.642 58.674 -36.930 1.00 25.91 ? 2702 HOH A O 1 HETATM 9177 O O . HOH F 6 . ? 26.299 66.969 19.972 1.00 28.43 ? 2703 HOH A O 1 HETATM 9178 O O . HOH F 6 . ? 11.727 41.467 19.738 1.00 29.68 ? 2704 HOH A O 1 HETATM 9179 O O . HOH F 6 . ? 69.427 77.115 -34.242 1.00 30.14 ? 2705 HOH A O 1 HETATM 9180 O O . HOH F 6 . ? 16.625 42.915 -2.531 1.00 29.23 ? 2706 HOH A O 1 HETATM 9181 O O . HOH F 6 . ? 34.628 66.189 -42.649 1.00 34.48 ? 2707 HOH A O 1 HETATM 9182 O O . HOH F 6 . ? 57.343 35.995 -14.292 1.00 30.95 ? 2708 HOH A O 1 HETATM 9183 O O . HOH F 6 . ? 37.354 37.614 2.880 1.00 34.95 ? 2709 HOH A O 1 HETATM 9184 O O . HOH F 6 . ? 51.463 66.713 8.470 1.00 24.00 ? 2710 HOH A O 1 HETATM 9185 O O . HOH F 6 . ? 10.749 51.479 21.361 1.00 24.99 ? 2711 HOH A O 1 HETATM 9186 O O . HOH F 6 . ? 30.367 87.284 -15.077 1.00 26.05 ? 2712 HOH A O 1 HETATM 9187 O O . HOH F 6 . ? 41.883 54.899 -17.322 1.00 27.69 ? 2713 HOH A O 1 HETATM 9188 O O . HOH F 6 . ? 48.442 76.586 8.260 1.00 35.37 ? 2714 HOH A O 1 HETATM 9189 O O . HOH F 6 . ? 29.838 75.647 11.013 1.00 29.39 ? 2715 HOH A O 1 HETATM 9190 O O . HOH F 6 . ? 43.222 98.126 -37.334 1.00 31.39 ? 2716 HOH A O 1 HETATM 9191 O O . HOH F 6 . ? 64.760 78.732 -1.694 1.00 27.28 ? 2717 HOH A O 1 HETATM 9192 O O . HOH F 6 . ? 43.403 40.614 -23.039 1.00 29.47 ? 2718 HOH A O 1 HETATM 9193 O O . HOH F 6 . ? 59.655 49.071 2.226 1.00 32.77 ? 2719 HOH A O 1 HETATM 9194 O O . HOH F 6 . ? 69.041 41.692 -17.172 1.00 38.36 ? 2720 HOH A O 1 HETATM 9195 O O . HOH F 6 . ? 24.724 71.763 -39.909 1.00 25.01 ? 2721 HOH A O 1 HETATM 9196 O O . HOH F 6 . ? 24.030 48.492 -24.253 1.00 33.96 ? 2722 HOH A O 1 HETATM 9197 O O . HOH F 6 . ? 47.111 68.306 -24.613 1.00 22.72 ? 2723 HOH A O 1 HETATM 9198 O O . HOH F 6 . ? 53.530 53.463 -30.182 1.00 27.95 ? 2724 HOH A O 1 HETATM 9199 O O . HOH F 6 . ? 24.612 34.494 35.817 1.00 33.37 ? 2725 HOH A O 1 HETATM 9200 O O . HOH F 6 . ? 13.157 52.449 25.926 1.00 32.58 ? 2726 HOH A O 1 HETATM 9201 O O . HOH F 6 . ? 51.861 44.556 3.124 1.00 21.52 ? 2727 HOH A O 1 HETATM 9202 O O . HOH F 6 . ? 21.686 55.357 40.157 1.00 29.94 ? 2728 HOH A O 1 HETATM 9203 O O . HOH F 6 . ? 64.269 70.716 -5.328 1.00 17.97 ? 2729 HOH A O 1 HETATM 9204 O O . HOH F 6 . ? 47.126 89.642 -23.451 1.00 39.50 ? 2730 HOH A O 1 HETATM 9205 O O . HOH F 6 . ? 8.123 53.213 -7.723 1.00 32.34 ? 2731 HOH A O 1 HETATM 9206 O O . HOH F 6 . ? 22.262 80.938 -42.537 1.00 30.46 ? 2732 HOH A O 1 HETATM 9207 O O . HOH F 6 . ? 64.090 65.445 -30.287 1.00 31.27 ? 2733 HOH A O 1 HETATM 9208 O O . HOH F 6 . ? 18.461 48.666 -19.844 1.00 39.43 ? 2734 HOH A O 1 HETATM 9209 O O . HOH F 6 . ? 59.375 76.982 -4.214 1.00 35.03 ? 2735 HOH A O 1 HETATM 9210 O O . HOH F 6 . ? 21.075 84.066 -12.388 1.00 33.91 ? 2736 HOH A O 1 HETATM 9211 O O . HOH F 6 . ? 19.446 52.181 -31.364 1.00 36.66 ? 2737 HOH A O 1 HETATM 9212 O O . HOH F 6 . ? 67.402 85.542 -36.151 1.00 41.60 ? 2738 HOH A O 1 HETATM 9213 O O . HOH F 6 . ? 29.671 75.056 22.367 1.00 24.96 ? 2739 HOH A O 1 HETATM 9214 O O . HOH F 6 . ? 32.897 84.372 0.381 1.00 27.96 ? 2740 HOH A O 1 HETATM 9215 O O . HOH F 6 . ? 12.918 62.078 -2.359 1.00 26.02 ? 2741 HOH A O 1 HETATM 9216 O O . HOH F 6 . ? 25.794 63.153 13.602 1.00 33.22 ? 2742 HOH A O 1 HETATM 9217 O O . HOH F 6 . ? 28.249 34.879 32.302 1.00 33.78 ? 2743 HOH A O 1 HETATM 9218 O O . HOH F 6 . ? 35.946 68.551 23.923 1.00 32.66 ? 2744 HOH A O 1 HETATM 9219 O O . HOH F 6 . ? 32.014 33.730 17.150 1.00 30.70 ? 2745 HOH A O 1 HETATM 9220 O O . HOH F 6 . ? 41.563 84.437 -2.027 1.00 43.12 ? 2746 HOH A O 1 HETATM 9221 O O . HOH F 6 . ? 40.049 100.142 -31.941 1.00 39.02 ? 2747 HOH A O 1 HETATM 9222 O O . HOH F 6 . ? 54.075 82.756 -44.908 1.00 41.73 ? 2748 HOH A O 1 HETATM 9223 O O . HOH F 6 . ? 70.257 53.651 -10.190 1.00 29.58 ? 2749 HOH A O 1 HETATM 9224 O O . HOH F 6 . ? 12.405 64.627 -12.473 1.00 30.27 ? 2750 HOH A O 1 HETATM 9225 O O . HOH F 6 . ? 39.342 50.206 36.394 1.00 37.56 ? 2751 HOH A O 1 HETATM 9226 O O . HOH F 6 . ? 28.055 44.577 38.319 1.00 31.62 ? 2752 HOH A O 1 HETATM 9227 O O . HOH F 6 . ? 72.444 95.791 -31.498 1.00 31.52 ? 2753 HOH A O 1 HETATM 9228 O O . HOH F 6 . ? 21.682 48.919 -38.935 1.00 39.36 ? 2754 HOH A O 1 HETATM 9229 O O . HOH F 6 . ? 20.994 31.667 31.559 1.00 41.11 ? 2755 HOH A O 1 HETATM 9230 O O . HOH F 6 . ? 42.760 47.378 -27.371 1.00 35.37 ? 2756 HOH A O 1 HETATM 9231 O O . HOH F 6 . ? 55.948 52.080 27.496 1.00 24.95 ? 2757 HOH A O 1 HETATM 9232 O O . HOH F 6 . ? 31.104 58.278 -40.350 1.00 35.88 ? 2758 HOH A O 1 HETATM 9233 O O . HOH F 6 . ? 62.159 81.550 -44.466 1.00 35.28 ? 2759 HOH A O 1 HETATM 9234 O O . HOH F 6 . ? 7.543 54.573 17.338 1.00 35.17 ? 2760 HOH A O 1 HETATM 9235 O O . HOH F 6 . ? 17.998 41.755 25.361 1.00 34.70 ? 2761 HOH A O 1 HETATM 9236 O O . HOH F 6 . ? 39.087 53.164 2.231 1.00 36.07 ? 2762 HOH A O 1 HETATM 9237 O O . HOH F 6 . ? 4.275 56.541 -6.412 1.00 28.47 ? 2763 HOH A O 1 HETATM 9238 O O . HOH F 6 . ? 22.147 76.819 8.815 1.00 29.93 ? 2764 HOH A O 1 HETATM 9239 O O . HOH F 6 . ? 25.875 87.979 -42.861 1.00 35.45 ? 2765 HOH A O 1 HETATM 9240 O O . HOH F 6 . ? 10.817 62.583 -12.144 1.00 31.71 ? 2766 HOH A O 1 HETATM 9241 O O . HOH F 6 . ? 44.571 71.997 -44.792 1.00 41.86 ? 2767 HOH A O 1 HETATM 9242 O O . HOH F 6 . ? 37.261 40.062 26.370 1.00 37.04 ? 2768 HOH A O 1 HETATM 9243 O O . HOH F 6 . ? 23.305 88.909 -37.872 1.00 32.92 ? 2769 HOH A O 1 HETATM 9244 O O . HOH F 6 . ? 70.134 62.867 -24.024 1.00 33.67 ? 2770 HOH A O 1 HETATM 9245 O O . HOH F 6 . ? 22.821 64.389 18.369 1.00 30.51 ? 2771 HOH A O 1 HETATM 9246 O O . HOH F 6 . ? 67.139 38.370 -9.800 1.00 31.63 ? 2772 HOH A O 1 HETATM 9247 O O . HOH F 6 . ? 65.707 88.171 -41.100 1.00 44.85 ? 2773 HOH A O 1 HETATM 9248 O O . HOH F 6 . ? 13.328 45.030 29.497 1.00 47.44 ? 2774 HOH A O 1 HETATM 9249 O O . HOH F 6 . ? 13.410 48.434 1.619 1.00 31.48 ? 2775 HOH A O 1 HETATM 9250 O O . HOH F 6 . ? 55.510 69.136 -37.839 1.00 28.64 ? 2776 HOH A O 1 HETATM 9251 O O . HOH F 6 . ? 27.004 47.653 -23.859 1.00 30.39 ? 2777 HOH A O 1 HETATM 9252 O O . HOH F 6 . ? 69.986 82.063 -34.131 1.00 38.71 ? 2778 HOH A O 1 HETATM 9253 O O . HOH F 6 . ? 11.935 62.152 23.023 1.00 37.56 ? 2779 HOH A O 1 HETATM 9254 O O . HOH F 6 . ? 31.135 29.795 5.577 1.00 42.21 ? 2780 HOH A O 1 HETATM 9255 O O . HOH F 6 . ? 19.187 36.514 22.577 1.00 36.89 ? 2781 HOH A O 1 HETATM 9256 O O . HOH F 6 . ? 27.834 86.429 -14.735 1.00 30.63 ? 2782 HOH A O 1 HETATM 9257 O O . HOH F 6 . ? 66.068 50.498 0.269 1.00 32.66 ? 2783 HOH A O 1 HETATM 9258 O O . HOH F 6 . ? 28.302 63.867 14.007 1.00 29.50 ? 2784 HOH A O 1 HETATM 9259 O O . HOH F 6 . ? 52.560 72.616 18.401 1.00 26.14 ? 2785 HOH A O 1 HETATM 9260 O O . HOH F 6 . ? 47.156 75.081 -26.357 1.00 34.14 ? 2786 HOH A O 1 HETATM 9261 O O . HOH F 6 . ? 48.764 72.384 -26.287 1.00 27.45 ? 2787 HOH A O 1 HETATM 9262 O O . HOH F 6 . ? 60.150 68.758 -38.912 1.00 29.70 ? 2788 HOH A O 1 HETATM 9263 O O . HOH F 6 . ? 59.214 55.395 27.094 1.00 23.66 ? 2789 HOH A O 1 HETATM 9264 O O . HOH F 6 . ? 43.908 87.774 -16.065 1.00 45.79 ? 2790 HOH A O 1 HETATM 9265 O O . HOH F 6 . ? 13.963 58.296 16.304 1.00 15.95 ? 2791 HOH A O 1 HETATM 9266 O O . HOH F 6 . ? 13.969 57.695 19.061 1.00 19.95 ? 2792 HOH A O 1 HETATM 9267 O O . HOH F 6 . ? 28.167 39.676 11.289 1.00 13.20 ? 2793 HOH A O 1 HETATM 9268 O O . HOH F 6 . ? 28.956 81.954 -35.751 1.00 18.41 ? 2794 HOH A O 1 HETATM 9269 O O . HOH F 6 . ? 12.410 55.876 -15.173 1.00 20.70 ? 2795 HOH A O 1 HETATM 9270 O O . HOH F 6 . ? 81.806 67.157 -13.671 1.00 22.51 ? 2796 HOH A O 1 HETATM 9271 O O . HOH F 6 . ? 59.134 58.245 0.987 1.00 23.52 ? 2797 HOH A O 1 HETATM 9272 O O . HOH F 6 . ? 49.510 68.368 6.681 1.00 22.39 ? 2798 HOH A O 1 HETATM 9273 O O . HOH F 6 . ? 68.587 79.435 -28.695 1.00 20.37 ? 2799 HOH A O 1 HETATM 9274 O O . HOH F 6 . ? 26.052 32.811 28.686 1.00 27.04 ? 2800 HOH A O 1 HETATM 9275 O O . HOH F 6 . ? 32.735 69.320 24.750 1.00 24.31 ? 2801 HOH A O 1 HETATM 9276 O O . HOH F 6 . ? 28.054 102.488 -19.334 1.00 22.92 ? 2802 HOH A O 1 HETATM 9277 O O . HOH F 6 . ? 71.869 73.918 -29.360 1.00 25.64 ? 2803 HOH A O 1 HETATM 9278 O O . HOH F 6 . ? 79.503 50.728 -9.035 1.00 29.00 ? 2804 HOH A O 1 HETATM 9279 O O . HOH F 6 . ? 37.437 83.524 -4.035 1.00 28.09 ? 2805 HOH A O 1 HETATM 9280 O O . HOH F 6 . ? 59.563 52.106 2.512 1.00 24.80 ? 2806 HOH A O 1 HETATM 9281 O O . HOH F 6 . ? 19.829 84.446 -18.370 1.00 30.06 ? 2807 HOH A O 1 HETATM 9282 O O . HOH F 6 . ? 44.206 79.279 -21.538 1.00 30.45 ? 2808 HOH A O 1 HETATM 9283 O O . HOH F 6 . ? 58.086 52.876 26.233 1.00 26.59 ? 2809 HOH A O 1 HETATM 9284 O O . HOH F 6 . ? 17.094 57.424 -36.491 1.00 30.96 ? 2810 HOH A O 1 HETATM 9285 O O . HOH F 6 . ? 46.828 42.978 9.643 1.00 34.07 ? 2811 HOH A O 1 HETATM 9286 O O . HOH F 6 . ? 27.178 72.219 34.069 1.00 33.90 ? 2812 HOH A O 1 HETATM 9287 O O . HOH F 6 . ? 7.549 54.182 -10.270 1.00 27.09 ? 2813 HOH A O 1 HETATM 9288 O O . HOH F 6 . ? 50.057 46.849 -30.681 1.00 32.71 ? 2814 HOH A O 1 HETATM 9289 O O . HOH F 6 . ? 42.772 78.561 -29.811 1.00 33.08 ? 2815 HOH A O 1 HETATM 9290 O O . HOH F 6 . ? 27.735 88.999 -12.160 1.00 33.84 ? 2816 HOH A O 1 HETATM 9291 O O . HOH F 6 . ? 56.768 89.973 -43.828 1.00 34.66 ? 2817 HOH A O 1 HETATM 9292 O O . HOH F 6 . ? 13.962 44.705 26.965 1.00 32.91 ? 2818 HOH A O 1 HETATM 9293 O O . HOH F 6 . ? 69.509 83.887 -36.192 1.00 28.92 ? 2819 HOH A O 1 HETATM 9294 O O . HOH F 6 . ? 58.201 93.304 -25.011 1.00 27.14 ? 2820 HOH A O 1 HETATM 9295 O O . HOH F 6 . ? 46.191 39.893 -0.062 1.00 27.20 ? 2821 HOH A O 1 HETATM 9296 O O . HOH F 6 . ? 37.186 37.502 25.052 1.00 36.14 ? 2822 HOH A O 1 HETATM 9297 O O . HOH F 6 . ? 52.737 68.331 4.681 1.00 29.61 ? 2823 HOH A O 1 HETATM 9298 O O . HOH F 6 . ? 17.835 50.899 38.098 1.00 45.71 ? 2824 HOH A O 1 HETATM 9299 O O . HOH F 6 . ? 15.365 77.106 -13.642 1.00 33.99 ? 2825 HOH A O 1 HETATM 9300 O O . HOH F 6 . ? 20.103 39.763 -12.634 1.00 42.77 ? 2826 HOH A O 1 HETATM 9301 O O . HOH F 6 . ? 49.546 45.653 31.068 1.00 23.68 ? 2827 HOH A O 1 HETATM 9302 O O . HOH F 6 . ? 70.748 78.049 -26.330 1.00 24.48 ? 2828 HOH A O 1 HETATM 9303 O O . HOH F 6 . ? 58.587 52.852 4.773 1.00 23.81 ? 2829 HOH A O 1 HETATM 9304 O O . HOH F 6 . ? 35.171 55.333 -34.654 1.00 40.30 ? 2830 HOH A O 1 HETATM 9305 O O . HOH F 6 . ? 41.439 82.933 -28.993 1.00 27.16 ? 2831 HOH A O 1 HETATM 9306 O O . HOH F 6 . ? 47.741 66.192 26.914 1.00 29.38 ? 2832 HOH A O 1 HETATM 9307 O O . HOH F 6 . ? 39.881 81.856 -22.151 1.00 31.85 ? 2833 HOH A O 1 HETATM 9308 O O . HOH F 6 . ? 22.152 65.665 32.304 1.00 30.23 ? 2834 HOH A O 1 HETATM 9309 O O . HOH F 6 . ? 58.939 48.811 19.120 1.00 28.91 ? 2835 HOH A O 1 HETATM 9310 O O . HOH F 6 . ? 32.003 80.403 7.190 1.00 41.92 ? 2836 HOH A O 1 HETATM 9311 O O . HOH F 6 . ? 50.589 44.984 -24.853 1.00 24.30 ? 2837 HOH A O 1 HETATM 9312 O O . HOH F 6 . ? 62.519 60.834 0.434 1.00 29.64 ? 2838 HOH A O 1 HETATM 9313 O O . HOH F 6 . ? 68.127 75.211 -35.201 1.00 28.63 ? 2839 HOH A O 1 HETATM 9314 O O . HOH F 6 . ? 22.989 39.311 -15.338 1.00 36.94 ? 2840 HOH A O 1 HETATM 9315 O O . HOH F 6 . ? 36.441 93.979 -29.726 1.00 37.64 ? 2841 HOH A O 1 HETATM 9316 O O . HOH F 6 . ? 74.182 79.998 -11.027 1.00 41.74 ? 2842 HOH A O 1 HETATM 9317 O O . HOH F 6 . ? 41.278 81.839 -3.740 1.00 36.78 ? 2843 HOH A O 1 HETATM 9318 O O . HOH F 6 . ? 13.237 63.002 11.895 1.00 29.31 ? 2844 HOH A O 1 HETATM 9319 O O . HOH F 6 . ? 56.945 76.085 0.077 1.00 38.07 ? 2845 HOH A O 1 HETATM 9320 O O . HOH F 6 . ? 74.511 52.176 1.409 1.00 30.58 ? 2846 HOH A O 1 HETATM 9321 O O . HOH F 6 . ? 21.560 61.500 -34.734 1.00 27.43 ? 2847 HOH A O 1 HETATM 9322 O O . HOH F 6 . ? 17.109 41.871 32.173 1.00 33.64 ? 2848 HOH A O 1 HETATM 9323 O O . HOH F 6 . ? 10.201 62.930 -14.849 1.00 36.89 ? 2849 HOH A O 1 HETATM 9324 O O . HOH F 6 . ? 46.143 79.849 4.763 1.00 28.45 ? 2850 HOH A O 1 HETATM 9325 O O . HOH F 6 . ? 14.526 46.959 32.442 1.00 28.33 ? 2851 HOH A O 1 HETATM 9326 O O . HOH F 6 . ? 47.514 40.257 5.984 1.00 40.34 ? 2852 HOH A O 1 HETATM 9327 O O . HOH F 6 . ? 19.981 39.303 -3.745 1.00 37.06 ? 2853 HOH A O 1 HETATM 9328 O O . HOH F 6 . ? 25.906 58.982 -39.104 1.00 34.40 ? 2854 HOH A O 1 HETATM 9329 O O . HOH F 6 . ? 10.497 58.075 -20.856 1.00 33.22 ? 2855 HOH A O 1 HETATM 9330 O O . HOH F 6 . ? 8.694 56.693 16.286 1.00 37.17 ? 2856 HOH A O 1 HETATM 9331 O O . HOH F 6 . ? 78.217 72.364 -10.277 1.00 29.23 ? 2857 HOH A O 1 HETATM 9332 O O . HOH F 6 . ? 24.176 83.188 -4.033 1.00 40.30 ? 2858 HOH A O 1 HETATM 9333 O O . HOH F 6 . ? 35.331 62.352 34.123 1.00 29.92 ? 2859 HOH A O 1 HETATM 9334 O O . HOH F 6 . ? 27.005 90.294 -31.562 1.00 39.06 ? 2860 HOH A O 1 HETATM 9335 O O . HOH F 6 . ? 74.867 77.267 -20.573 1.00 34.32 ? 2861 HOH A O 1 HETATM 9336 O O . HOH F 6 . ? 49.124 41.835 8.240 1.00 31.52 ? 2862 HOH A O 1 HETATM 9337 O O . HOH F 6 . ? 44.999 92.694 -25.475 1.00 34.59 ? 2863 HOH A O 1 HETATM 9338 O O . HOH F 6 . ? 52.422 48.957 25.725 1.00 29.67 ? 2864 HOH A O 1 HETATM 9339 O O . HOH F 6 . ? 58.912 51.030 14.934 1.00 32.92 ? 2865 HOH A O 1 HETATM 9340 O O . HOH F 6 . ? 52.023 50.472 27.475 1.00 25.40 ? 2866 HOH A O 1 HETATM 9341 O O . HOH F 6 . ? 11.530 58.413 20.044 1.00 34.14 ? 2867 HOH A O 1 HETATM 9342 O O . HOH F 6 . ? 18.884 60.706 -38.038 1.00 24.45 ? 2868 HOH A O 1 HETATM 9343 O O . HOH F 6 . ? 45.684 60.137 -31.738 1.00 41.98 ? 2869 HOH A O 1 HETATM 9344 O O . HOH F 6 . ? 5.375 57.737 6.959 1.00 33.65 ? 2870 HOH A O 1 HETATM 9345 O O . HOH F 6 . ? 47.427 81.476 -17.125 1.00 24.15 ? 2871 HOH A O 1 HETATM 9346 O O . HOH F 6 . ? 28.896 69.628 12.567 1.00 37.87 ? 2872 HOH A O 1 HETATM 9347 O O . HOH F 6 . ? 31.778 72.172 13.605 1.00 34.98 ? 2873 HOH A O 1 HETATM 9348 O O . HOH F 6 . ? 25.664 66.125 17.259 1.00 35.33 ? 2874 HOH A O 1 HETATM 9349 O O . HOH F 6 . ? 78.913 62.575 -23.064 1.00 38.05 ? 2875 HOH A O 1 HETATM 9350 O O . HOH F 6 . ? 29.724 66.204 10.792 1.00 25.98 ? 2876 HOH A O 1 HETATM 9351 O O . HOH F 6 . ? 28.683 63.592 10.971 1.00 26.76 ? 2877 HOH A O 1 HETATM 9352 O O . HOH F 6 . ? 33.819 68.708 13.644 1.00 21.68 ? 2878 HOH A O 1 HETATM 9353 O O . HOH F 6 . ? 24.317 63.448 11.653 1.00 32.62 ? 2879 HOH A O 1 HETATM 9354 O O . HOH F 6 . ? 33.480 68.792 17.492 1.00 38.34 ? 2880 HOH A O 1 HETATM 9355 O O . HOH F 6 . ? 37.540 59.040 11.097 1.00 15.17 ? 2881 HOH A O 1 HETATM 9356 O O . HOH F 6 . ? 26.666 75.005 2.197 1.00 20.92 ? 2882 HOH A O 1 HETATM 9357 O O . HOH F 6 . ? 24.806 33.089 6.523 1.00 25.27 ? 2883 HOH A O 1 HETATM 9358 O O . HOH F 6 . ? 53.674 66.538 6.953 1.00 28.68 ? 2884 HOH A O 1 HETATM 9359 O O . HOH F 6 . ? 39.009 86.662 -41.619 1.00 27.46 ? 2885 HOH A O 1 HETATM 9360 O O . HOH F 6 . ? 52.596 45.543 -27.366 1.00 33.03 ? 2886 HOH A O 1 HETATM 9361 O O . HOH F 6 . ? 52.053 69.291 9.512 1.00 30.96 ? 2887 HOH A O 1 HETATM 9362 O O . HOH F 6 . ? 56.537 66.924 5.350 1.00 33.77 ? 2888 HOH A O 1 HETATM 9363 O O . HOH F 6 . ? 74.043 54.098 -13.901 1.00 40.32 ? 2889 HOH A O 1 HETATM 9364 O O . HOH F 6 . ? 47.415 41.394 -14.883 1.00 24.85 ? 2890 HOH A O 1 HETATM 9365 O O . HOH F 6 . ? 39.089 60.486 11.794 1.00 25.44 ? 2891 HOH A O 1 HETATM 9366 O O . HOH F 6 . ? 38.823 80.418 -3.347 1.00 26.04 ? 2892 HOH A O 1 HETATM 9367 O O . HOH F 6 . ? 47.561 78.433 11.524 1.00 30.09 ? 2893 HOH A O 1 HETATM 9368 O O . HOH F 6 . ? 34.897 66.317 12.449 1.00 22.93 ? 2894 HOH A O 1 HETATM 9369 O O . HOH F 6 . ? 27.214 65.346 9.198 1.00 27.13 ? 2895 HOH A O 1 HETATM 9370 O O . HOH F 6 . ? 75.598 73.842 -16.298 1.00 33.50 ? 2896 HOH A O 1 HETATM 9371 O O . HOH F 6 . ? 30.160 59.207 35.312 1.00 29.59 ? 2897 HOH A O 1 HETATM 9372 O O . HOH F 6 . ? 43.472 64.536 -31.451 1.00 28.04 ? 2898 HOH A O 1 HETATM 9373 O O . HOH F 6 . ? 14.717 55.064 -26.397 1.00 32.71 ? 2899 HOH A O 1 HETATM 9374 O O . HOH F 6 . ? 70.334 60.453 -23.330 1.00 33.40 ? 2900 HOH A O 1 HETATM 9375 O O . HOH F 6 . ? 63.563 59.689 17.038 1.00 29.62 ? 2901 HOH A O 1 HETATM 9376 O O . HOH F 6 . ? 28.905 64.516 30.233 1.00 25.09 ? 2902 HOH A O 1 HETATM 9377 O O . HOH F 6 . ? 7.920 81.178 -4.292 1.00 31.00 ? 2903 HOH A O 1 HETATM 9378 O O . HOH F 6 . ? 56.160 53.500 29.837 1.00 34.93 ? 2904 HOH A O 1 HETATM 9379 O O . HOH F 6 . ? 49.823 41.011 1.304 1.00 31.17 ? 2905 HOH A O 1 HETATM 9380 O O . HOH F 6 . ? 15.512 73.742 5.380 1.00 31.66 ? 2906 HOH A O 1 HETATM 9381 O O . HOH F 6 . ? 38.366 73.838 18.211 1.00 28.02 ? 2907 HOH A O 1 HETATM 9382 O O . HOH F 6 . ? 49.476 46.029 26.618 1.00 34.09 ? 2908 HOH A O 1 HETATM 9383 O O . HOH F 6 . ? 50.171 58.456 -31.147 1.00 32.36 ? 2909 HOH A O 1 HETATM 9384 O O . HOH F 6 . ? 17.824 66.596 30.737 1.00 33.28 ? 2910 HOH A O 1 HETATM 9385 O O . HOH F 6 . ? 60.512 91.189 -31.408 1.00 30.73 ? 2911 HOH A O 1 HETATM 9386 O O . HOH F 6 . ? 18.296 36.782 5.881 1.00 32.74 ? 2912 HOH A O 1 HETATM 9387 O O . HOH F 6 . ? 36.068 63.572 -34.005 1.00 32.90 ? 2913 HOH A O 1 HETATM 9388 O O . HOH F 6 . ? 59.941 45.458 16.370 1.00 40.74 ? 2914 HOH A O 1 HETATM 9389 O O . HOH F 6 . ? 35.529 85.138 -0.937 1.00 35.28 ? 2915 HOH A O 1 HETATM 9390 O O . HOH F 6 . ? 46.383 70.511 -39.858 1.00 31.17 ? 2916 HOH A O 1 HETATM 9391 O O . HOH F 6 . ? 42.403 68.990 26.280 1.00 35.34 ? 2917 HOH A O 1 HETATM 9392 O O . HOH F 6 . ? 57.682 49.327 16.594 1.00 28.55 ? 2918 HOH A O 1 HETATM 9393 O O . HOH F 6 . ? 45.489 71.897 -25.972 1.00 28.07 ? 2919 HOH A O 1 HETATM 9394 O O . HOH F 6 . ? 5.324 81.191 -3.335 1.00 35.73 ? 2920 HOH A O 1 HETATM 9395 O O . HOH F 6 . ? 53.990 40.764 -20.635 1.00 35.36 ? 2921 HOH A O 1 HETATM 9396 O O . HOH F 6 . ? 31.952 96.832 -27.393 1.00 32.12 ? 2922 HOH A O 1 HETATM 9397 O O . HOH F 6 . ? 21.876 47.112 -34.474 1.00 39.11 ? 2923 HOH A O 1 HETATM 9398 O O . HOH F 6 . ? 61.547 68.870 -41.559 1.00 37.94 ? 2924 HOH A O 1 HETATM 9399 O O . HOH F 6 . ? 29.569 102.300 -16.665 1.00 33.49 ? 2925 HOH A O 1 HETATM 9400 O O . HOH F 6 . ? 26.260 57.603 40.498 1.00 39.31 ? 2926 HOH A O 1 HETATM 9401 O O . HOH F 6 . ? 65.406 41.458 -20.938 1.00 34.25 ? 2927 HOH A O 1 HETATM 9402 O O . HOH F 6 . ? 44.388 40.886 7.809 1.00 36.96 ? 2928 HOH A O 1 HETATM 9403 O O . HOH F 6 . ? 56.790 69.988 -39.703 1.00 34.55 ? 2929 HOH A O 1 HETATM 9404 O O . HOH F 6 . ? 36.163 70.349 19.258 1.00 32.10 ? 2930 HOH A O 1 HETATM 9405 O O . HOH F 6 . ? 55.361 68.561 3.449 1.00 38.95 ? 2931 HOH A O 1 HETATM 9406 O O . HOH F 6 . ? 65.746 77.522 2.889 1.00 36.96 ? 2932 HOH A O 1 HETATM 9407 O O . HOH F 6 . ? 57.004 39.057 -19.461 1.00 29.86 ? 2933 HOH A O 1 HETATM 9408 O O . HOH F 6 . ? 24.619 33.071 9.548 1.00 31.15 ? 2934 HOH A O 1 HETATM 9409 O O . HOH F 6 . ? 50.089 79.975 -11.194 1.00 38.33 ? 2935 HOH A O 1 HETATM 9410 O O . HOH F 6 . ? 7.206 51.512 9.321 1.00 39.30 ? 2936 HOH A O 1 HETATM 9411 O O . HOH F 6 . ? 36.303 78.740 11.618 1.00 33.66 ? 2937 HOH A O 1 HETATM 9412 O O . HOH F 6 . ? 51.837 41.101 -13.148 1.00 32.29 ? 2938 HOH A O 1 HETATM 9413 O O . HOH F 6 . ? 34.214 86.799 -43.811 1.00 35.69 ? 2939 HOH A O 1 HETATM 9414 O O . HOH F 6 . ? 67.865 77.315 -38.769 1.00 39.48 ? 2940 HOH A O 1 HETATM 9415 O O . HOH F 6 . ? 25.788 36.335 -15.435 1.00 30.29 ? 2941 HOH A O 1 HETATM 9416 O O . HOH F 6 . ? 36.734 70.958 16.696 1.00 35.84 ? 2942 HOH A O 1 HETATM 9417 O O . HOH F 6 . ? 68.815 57.253 -21.945 1.00 31.23 ? 2943 HOH A O 1 HETATM 9418 O O . HOH F 6 . ? 47.609 100.022 -33.100 1.00 36.10 ? 2944 HOH A O 1 HETATM 9419 O O . HOH F 6 . ? 60.391 51.439 6.231 1.00 31.36 ? 2945 HOH A O 1 HETATM 9420 O O . HOH F 6 . ? 50.034 50.129 36.929 1.00 34.09 ? 2946 HOH A O 1 HETATM 9421 O O . HOH F 6 . ? 29.582 35.077 -16.428 1.00 32.06 ? 2947 HOH A O 1 HETATM 9422 O O . HOH F 6 . ? 19.128 81.488 -27.393 1.00 44.32 ? 2948 HOH A O 1 HETATM 9423 O O . HOH F 6 . ? 44.844 80.665 12.626 1.00 37.48 ? 2949 HOH A O 1 HETATM 9424 O O . HOH F 6 . ? 59.731 68.674 16.454 1.00 32.60 ? 2950 HOH A O 1 HETATM 9425 O O . HOH F 6 . ? 20.460 50.901 -37.936 1.00 35.62 ? 2951 HOH A O 1 HETATM 9426 O O . HOH F 6 . ? 43.838 42.911 -24.763 1.00 34.09 ? 2952 HOH A O 1 HETATM 9427 O O . HOH F 6 . ? 49.708 62.058 -33.921 1.00 31.00 ? 2953 HOH A O 1 HETATM 9428 O O . HOH F 6 . ? 47.746 43.804 30.411 1.00 35.89 ? 2954 HOH A O 1 HETATM 9429 O O . HOH F 6 . ? 23.863 65.491 -43.783 1.00 40.64 ? 2955 HOH A O 1 HETATM 9430 O O . HOH F 6 . ? 35.497 73.698 15.123 1.00 35.23 ? 2956 HOH A O 1 HETATM 9431 O O . HOH F 6 . ? 22.119 34.667 12.587 1.00 39.44 ? 2957 HOH A O 1 HETATM 9432 O O . HOH F 6 . ? 68.242 88.189 -35.363 1.00 34.15 ? 2958 HOH A O 1 HETATM 9433 O O . HOH F 6 . ? 49.702 84.148 -19.116 1.00 33.22 ? 2959 HOH A O 1 HETATM 9434 O O . HOH F 6 . ? 60.870 46.828 -22.453 1.00 35.64 ? 2960 HOH A O 1 HETATM 9435 O O . HOH F 6 . ? 14.381 47.264 26.969 1.00 42.74 ? 2961 HOH A O 1 HETATM 9436 O O . HOH F 6 . ? 23.467 87.287 -16.506 1.00 39.43 ? 2962 HOH A O 1 HETATM 9437 O O . HOH F 6 . ? 34.961 36.652 3.404 1.00 33.75 ? 2963 HOH A O 1 HETATM 9438 O O . HOH F 6 . ? 11.404 62.251 5.266 1.00 42.79 ? 2964 HOH A O 1 HETATM 9439 O O . HOH F 6 . ? 58.768 43.997 -28.135 1.00 31.96 ? 2965 HOH A O 1 HETATM 9440 O O . HOH F 6 . ? 63.937 57.132 0.928 1.00 32.70 ? 2966 HOH A O 1 HETATM 9441 O O . HOH F 6 . ? 75.630 75.951 -5.990 1.00 41.49 ? 2967 HOH A O 1 HETATM 9442 O O . HOH F 6 . ? 12.163 47.372 31.355 1.00 36.21 ? 2968 HOH A O 1 HETATM 9443 O O . HOH F 6 . ? 45.770 56.542 -32.759 1.00 34.77 ? 2969 HOH A O 1 HETATM 9444 O O . HOH F 6 . ? 74.676 60.169 -9.674 1.00 34.26 ? 2970 HOH A O 1 HETATM 9445 O O . HOH F 6 . ? 60.845 80.116 -12.161 1.00 31.81 ? 2971 HOH A O 1 HETATM 9446 O O . HOH F 6 . ? 22.571 59.752 38.353 1.00 44.01 ? 2972 HOH A O 1 HETATM 9447 O O . HOH F 6 . ? 64.305 49.566 -21.859 1.00 42.05 ? 2973 HOH A O 1 HETATM 9448 O O . HOH F 6 . ? 38.283 87.030 -16.960 1.00 37.23 ? 2974 HOH A O 1 HETATM 9449 O O . HOH F 6 . ? 58.353 64.756 26.709 1.00 35.31 ? 2975 HOH A O 1 HETATM 9450 O O . HOH F 6 . ? 36.505 65.905 22.309 1.00 33.61 ? 2976 HOH A O 1 HETATM 9451 O O . HOH F 6 . ? 43.616 81.114 -25.380 1.00 39.65 ? 2977 HOH A O 1 HETATM 9452 O O . HOH F 6 . ? 52.032 71.558 22.131 1.00 33.73 ? 2978 HOH A O 1 HETATM 9453 O O . HOH F 6 . ? 22.210 35.155 35.051 1.00 39.20 ? 2979 HOH A O 1 HETATM 9454 O O . HOH F 6 . ? 61.044 61.464 13.657 1.00 34.19 ? 2980 HOH A O 1 HETATM 9455 O O . HOH F 6 . ? 16.132 30.998 18.139 1.00 42.47 ? 2981 HOH A O 1 HETATM 9456 O O . HOH F 6 . ? 62.894 82.809 -17.401 1.00 35.68 ? 2982 HOH A O 1 HETATM 9457 O O . HOH F 6 . ? 40.790 36.448 8.709 1.00 34.51 ? 2983 HOH A O 1 HETATM 9458 O O . HOH F 6 . ? 26.302 75.095 10.877 1.00 39.23 ? 2984 HOH A O 1 HETATM 9459 O O . HOH F 6 . ? 25.300 34.582 -7.029 1.00 41.50 ? 2985 HOH A O 1 HETATM 9460 O O . HOH F 6 . ? 29.806 66.902 16.214 1.00 47.51 ? 2986 HOH A O 1 HETATM 9461 O O . HOH F 6 . ? 69.488 63.845 2.037 1.00 41.51 ? 2987 HOH A O 1 HETATM 9462 O O . HOH F 6 . ? 18.972 39.661 26.387 1.00 34.36 ? 2988 HOH A O 1 HETATM 9463 O O . HOH F 6 . ? 24.665 87.320 -1.007 1.00 40.38 ? 2989 HOH A O 1 HETATM 9464 O O . HOH F 6 . ? 43.995 55.115 -26.876 1.00 30.63 ? 2990 HOH A O 1 HETATM 9465 O O . HOH F 6 . ? 15.153 69.909 24.297 1.00 37.07 ? 2991 HOH A O 1 HETATM 9466 O O . HOH F 6 . ? 18.687 37.617 19.691 1.00 33.23 ? 2992 HOH A O 1 HETATM 9467 O O . HOH F 6 . ? 50.953 90.903 -21.719 1.00 36.60 ? 2993 HOH A O 1 HETATM 9468 O O . HOH F 6 . ? 36.974 35.913 -18.633 1.00 41.17 ? 2994 HOH A O 1 HETATM 9469 O O . HOH F 6 . ? 45.237 58.143 32.357 1.00 40.35 ? 2995 HOH A O 1 HETATM 9470 O O . HOH F 6 . ? 62.919 44.707 -0.555 1.00 33.95 ? 2996 HOH A O 1 HETATM 9471 O O . HOH F 6 . ? 17.888 35.221 13.263 1.00 40.72 ? 2997 HOH A O 1 HETATM 9472 O O . HOH F 6 . ? 26.781 99.057 -26.516 1.00 36.37 ? 2998 HOH A O 1 HETATM 9473 O O . HOH F 6 . ? 27.324 30.885 30.574 1.00 41.71 ? 2999 HOH A O 1 HETATM 9474 O O . HOH F 6 . ? 56.140 49.294 27.242 1.00 36.73 ? 3000 HOH A O 1 HETATM 9475 O O . HOH F 6 . ? 38.627 54.335 -17.591 1.00 34.75 ? 3001 HOH A O 1 HETATM 9476 O O . HOH F 6 . ? 75.338 52.547 -15.873 1.00 36.46 ? 3002 HOH A O 1 HETATM 9477 O O . HOH F 6 . ? 13.989 88.294 -20.142 1.00 34.32 ? 3003 HOH A O 1 HETATM 9478 O O . HOH F 6 . ? 25.698 88.026 -15.946 1.00 38.75 ? 3004 HOH A O 1 HETATM 9479 O O . HOH F 6 . ? 63.951 45.636 -3.064 1.00 38.78 ? 3005 HOH A O 1 HETATM 9480 O O . HOH F 6 . ? 44.698 76.233 -28.476 1.00 39.79 ? 3006 HOH A O 1 HETATM 9481 O O . HOH F 6 . ? 73.741 63.138 -0.760 1.00 37.81 ? 3007 HOH A O 1 HETATM 9482 O O . HOH F 6 . ? 19.430 50.425 -23.654 1.00 37.08 ? 3008 HOH A O 1 HETATM 9483 O O . HOH F 6 . ? 58.459 37.353 -17.931 1.00 39.94 ? 3009 HOH A O 1 HETATM 9484 O O . HOH F 6 . ? 16.137 53.241 -25.741 1.00 47.38 ? 3010 HOH A O 1 HETATM 9485 O O . HOH F 6 . ? 46.143 94.994 -37.779 1.00 38.67 ? 3011 HOH A O 1 HETATM 9486 O O . HOH F 6 . ? 22.315 68.120 -40.183 1.00 33.90 ? 3012 HOH A O 1 HETATM 9487 O O . HOH F 6 . ? 41.981 58.443 34.644 1.00 38.65 ? 3013 HOH A O 1 HETATM 9488 O O . HOH F 6 . ? 63.875 82.665 -14.647 1.00 33.69 ? 3014 HOH A O 1 HETATM 9489 O O . HOH F 6 . ? 27.716 39.699 -24.784 1.00 46.79 ? 3015 HOH A O 1 HETATM 9490 O O . HOH F 6 . ? 58.113 48.468 25.584 1.00 44.48 ? 3016 HOH A O 1 HETATM 9491 O O . HOH F 6 . ? 19.585 81.732 -42.485 1.00 39.07 ? 3017 HOH A O 1 HETATM 9492 O O . HOH F 6 . ? 36.182 42.260 -26.732 1.00 43.68 ? 3018 HOH A O 1 HETATM 9493 O O . HOH F 6 . ? 60.521 54.397 14.909 1.00 28.49 ? 3019 HOH A O 1 HETATM 9494 O O . HOH F 6 . ? 29.483 41.176 -25.686 1.00 25.27 ? 3020 HOH A O 1 HETATM 9495 O O . HOH F 6 . ? 10.158 58.118 -3.251 1.00 30.26 ? 3021 HOH A O 1 HETATM 9496 O O . HOH F 6 . ? 55.267 93.694 -31.647 1.00 32.62 ? 3022 HOH A O 1 HETATM 9497 O O . HOH F 6 . ? 39.433 38.311 -10.786 1.00 33.56 ? 3023 HOH A O 1 HETATM 9498 O O . HOH F 6 . ? 35.646 67.975 20.598 1.00 33.14 ? 3024 HOH A O 1 HETATM 9499 O O . HOH F 6 . ? 32.632 69.621 22.264 1.00 30.25 ? 3025 HOH A O 1 HETATM 9500 O O . HOH F 6 . ? 10.829 53.706 4.070 1.00 28.58 ? 3026 HOH A O 1 HETATM 9501 O O . HOH F 6 . ? 61.001 56.181 2.033 1.00 35.82 ? 3027 HOH A O 1 HETATM 9502 O O . HOH F 6 . ? 56.851 47.063 23.230 1.00 35.29 ? 3028 HOH A O 1 HETATM 9503 O O . HOH F 6 . ? 22.906 77.397 -27.416 1.00 33.76 ? 3029 HOH A O 1 HETATM 9504 O O . HOH F 6 . ? 42.196 40.641 -9.885 1.00 33.53 ? 3030 HOH A O 1 HETATM 9505 O O . HOH F 6 . ? 29.793 29.888 24.298 1.00 39.98 ? 3031 HOH A O 1 HETATM 9506 O O . HOH F 6 . ? 52.033 60.454 28.200 1.00 31.35 ? 3032 HOH A O 1 HETATM 9507 O O . HOH F 6 . ? 22.837 88.529 -18.746 1.00 40.87 ? 3033 HOH A O 1 HETATM 9508 O O . HOH F 6 . ? 70.484 62.018 -0.058 1.00 34.07 ? 3034 HOH A O 1 HETATM 9509 O O . HOH F 6 . ? 39.950 45.306 -26.561 1.00 39.15 ? 3035 HOH A O 1 HETATM 9510 O O . HOH F 6 . ? 14.264 68.665 5.261 1.00 38.16 ? 3036 HOH A O 1 HETATM 9511 O O . HOH F 6 . ? 46.274 43.739 28.239 1.00 41.94 ? 3037 HOH A O 1 HETATM 9512 O O . HOH F 6 . ? 10.353 62.288 1.940 1.00 37.90 ? 3038 HOH A O 1 HETATM 9513 O O . HOH F 6 . ? 12.697 55.173 25.270 1.00 39.31 ? 3039 HOH A O 1 HETATM 9514 O O . HOH F 6 . ? 31.802 92.699 -36.749 1.00 27.29 ? 3040 HOH A O 1 HETATM 9515 O O . HOH F 6 . ? 47.074 72.636 -17.636 1.00 27.14 ? 3041 HOH A O 1 HETATM 9516 O O . HOH F 6 . ? 21.785 37.980 15.610 1.00 33.11 ? 3042 HOH A O 1 HETATM 9517 O O . HOH F 6 . ? 38.307 87.210 -19.975 1.00 38.85 ? 3043 HOH A O 1 HETATM 9518 O O . HOH F 6 . ? 46.858 45.642 26.321 1.00 34.80 ? 3044 HOH A O 1 HETATM 9519 O O . HOH F 6 . ? 21.025 68.862 -31.601 1.00 30.98 ? 3045 HOH A O 1 HETATM 9520 O O . HOH F 6 . ? 26.016 65.341 8.194 1.00 31.71 ? 3046 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 SER 3 3 ? ? ? A . n A 1 4 HIS 4 4 ? ? ? A . n A 1 5 HIS 5 5 ? ? ? A . n A 1 6 HIS 6 6 ? ? ? A . n A 1 7 HIS 7 7 ? ? ? A . n A 1 8 HIS 8 8 ? ? ? A . n A 1 9 HIS 9 9 ? ? ? A . n A 1 10 GLY 10 10 ? ? ? A . n A 1 11 GLU 11 11 ? ? ? A . n A 1 12 PHE 12 12 ? ? ? A . n A 1 13 ASP 13 13 ? ? ? A . n A 1 14 ASP 14 14 ? ? ? A . n A 1 15 PRO 15 15 ? ? ? A . n A 1 16 ILE 16 16 ? ? ? A . n A 1 17 ARG 17 17 ? ? ? A . n A 1 18 PRO 18 18 ? ? ? A . n A 1 19 PRO 19 19 ? ? ? A . n A 1 20 LEU 20 20 ? ? ? A . n A 1 21 LYS 21 21 ? ? ? A . n A 1 22 VAL 22 22 ? ? ? A . n A 1 23 ALA 23 23 ? ? ? A . n A 1 24 ARG 24 24 ? ? ? A . n A 1 25 SER 25 25 ? ? ? A . n A 1 26 PRO 26 26 ? ? ? A . n A 1 27 ARG 27 27 ? ? ? A . n A 1 28 PRO 28 28 ? ? ? A . n A 1 29 GLY 29 29 ? ? ? A . n A 1 30 GLN 30 30 ? ? ? A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 GLN 32 32 32 GLN GLN A . n A 1 33 ASP 33 33 33 ASP ASP A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 VAL 35 35 35 VAL VAL A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 ASP 37 37 37 ASP ASP A . n A 1 38 VAL 38 38 38 VAL VAL A . n A 1 39 PRO 39 39 39 PRO PRO A . n A 1 40 ASN 40 40 40 ASN ASN A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 VAL 43 43 43 VAL VAL A . n A 1 44 GLN 44 44 44 GLN GLN A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 LEU 48 48 48 LEU LEU A . n A 1 49 TYR 49 49 49 TYR TYR A . n A 1 50 ASP 50 50 50 ASP ASP A . n A 1 51 ARG 51 51 51 ARG ARG A . n A 1 52 MET 52 52 52 MET MET A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 LYS 55 55 55 LYS LYS A . n A 1 56 ASP 56 56 56 ASP ASP A . n A 1 57 ILE 57 57 57 ILE ILE A . n A 1 58 ASP 58 58 58 ASP ASP A . n A 1 59 GLY 59 59 59 GLY GLY A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 VAL 61 61 61 VAL VAL A . n A 1 62 TRP 62 62 62 TRP TRP A . n A 1 63 LYS 63 63 63 LYS LYS A . n A 1 64 GLN 64 64 64 GLN GLN A . n A 1 65 GLY 65 65 65 GLY GLY A . n A 1 66 TRP 66 66 66 TRP TRP A . n A 1 67 ASN 67 67 67 ASN ASN A . n A 1 68 ILE 68 68 68 ILE ILE A . n A 1 69 LYS 69 69 69 LYS LYS A . n A 1 70 TYR 70 70 70 TYR TYR A . n A 1 71 ASP 71 71 71 ASP ASP A . n A 1 72 PRO 72 72 72 PRO PRO A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 LYS 74 74 74 LYS LYS A . n A 1 75 TYR 75 75 75 TYR TYR A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 HIS 78 78 78 HIS HIS A . n A 1 79 HIS 79 79 79 HIS HIS A . n A 1 80 LYS 80 80 80 LYS LYS A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 LYS 82 82 82 LYS LYS A . n A 1 83 VAL 83 83 83 VAL VAL A . n A 1 84 PHE 84 84 84 PHE PHE A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 PRO 87 87 87 PRO PRO A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 HIS 90 90 90 HIS HIS A . n A 1 91 ASN 91 91 91 ASN ASN A . n A 1 92 ASP 92 92 92 ASP ASP A . n A 1 93 PRO 93 93 93 PRO PRO A . n A 1 94 GLY 94 94 94 GLY GLY A . n A 1 95 TRP 95 95 95 TRP TRP A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 GLN 97 97 97 GLN GLN A . n A 1 98 THR 98 98 98 THR THR A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 GLU 100 100 100 GLU GLU A . n A 1 101 GLU 101 101 101 GLU GLU A . n A 1 102 TYR 102 102 102 TYR TYR A . n A 1 103 TYR 103 103 103 TYR TYR A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 HIS 105 105 105 HIS HIS A . n A 1 106 ASP 106 106 106 ASP ASP A . n A 1 107 THR 107 107 107 THR THR A . n A 1 108 LYS 108 108 108 LYS LYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 LEU 111 111 111 LEU LEU A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 ASN 113 113 113 ASN ASN A . n A 1 114 ALA 114 114 114 ALA ALA A . n A 1 115 LEU 115 115 115 LEU LEU A . n A 1 116 ARG 116 116 116 ARG ARG A . n A 1 117 HIS 117 117 117 HIS HIS A . n A 1 118 LEU 118 118 118 LEU LEU A . n A 1 119 HIS 119 119 119 HIS HIS A . n A 1 120 ASP 120 120 120 ASP ASP A . n A 1 121 ASN 121 121 121 ASN ASN A . n A 1 122 PRO 122 122 122 PRO PRO A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 MET 124 124 124 MET MET A . n A 1 125 LYS 125 125 125 LYS LYS A . n A 1 126 PHE 126 126 126 PHE PHE A . n A 1 127 ILE 127 127 127 ILE ILE A . n A 1 128 TRP 128 128 128 TRP TRP A . n A 1 129 ALA 129 129 129 ALA ALA A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 SER 132 132 132 SER SER A . n A 1 133 TYR 133 133 133 TYR TYR A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ALA 135 135 135 ALA ALA A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 HIS 139 139 139 HIS HIS A . n A 1 140 ASP 140 140 140 ASP ASP A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 GLY 142 142 142 GLY GLY A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 ASN 144 144 144 ASN ASN A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 LYS 146 146 146 LYS LYS A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 GLN 148 148 148 GLN GLN A . n A 1 149 MET 149 149 149 MET MET A . n A 1 150 LYS 150 150 150 LYS LYS A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 ILE 152 152 152 ILE ILE A . n A 1 153 VAL 153 153 153 VAL VAL A . n A 1 154 LYS 154 154 154 LYS LYS A . n A 1 155 ASN 155 155 155 ASN ASN A . n A 1 156 GLY 156 156 156 GLY GLY A . n A 1 157 GLN 157 157 157 GLN GLN A . n A 1 158 LEU 158 158 158 LEU LEU A . n A 1 159 GLU 159 159 159 GLU GLU A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 VAL 161 161 161 VAL VAL A . n A 1 162 THR 162 162 162 THR THR A . n A 1 163 GLY 163 163 163 GLY GLY A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 TRP 165 165 165 TRP TRP A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 MET 167 167 167 MET MET A . n A 1 168 PRO 168 168 168 PRO PRO A . n A 1 169 ASP 169 169 169 ASP ASP A . n A 1 170 GLU 170 170 170 GLU GLU A . n A 1 171 ALA 171 171 171 ALA ALA A . n A 1 172 ASN 172 172 172 ASN ASN A . n A 1 173 SER 173 173 173 SER SER A . n A 1 174 HIS 174 174 174 HIS HIS A . n A 1 175 TRP 175 175 175 TRP TRP A . n A 1 176 ARG 176 176 176 ARG ARG A . n A 1 177 ASN 177 177 177 ASN ASN A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLN 181 181 181 GLN GLN A . n A 1 182 LEU 182 182 182 LEU LEU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 GLY 185 185 185 GLY GLY A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 TRP 188 188 188 TRP TRP A . n A 1 189 LEU 189 189 189 LEU LEU A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 PHE 192 192 192 PHE PHE A . n A 1 193 MET 193 193 193 MET MET A . n A 1 194 ASN 194 194 194 ASN ASN A . n A 1 195 VAL 195 195 195 VAL VAL A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 THR 198 198 198 THR THR A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 SER 200 200 200 SER SER A . n A 1 201 TRP 201 201 201 TRP TRP A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 ILE 203 203 203 ILE ILE A . n A 1 204 ASP 204 204 204 ASP ASP A . n A 1 205 PRO 205 205 205 PRO PRO A . n A 1 206 PHE 206 206 206 PHE PHE A . n A 1 207 GLY 207 207 207 GLY GLY A . n A 1 208 HIS 208 208 208 HIS HIS A . n A 1 209 SER 209 209 209 SER SER A . n A 1 210 PRO 210 210 210 PRO PRO A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 MET 212 212 212 MET MET A . n A 1 213 PRO 213 213 213 PRO PRO A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 LYS 218 218 218 LYS LYS A . n A 1 219 SER 219 219 219 SER SER A . n A 1 220 GLY 220 220 220 GLY GLY A . n A 1 221 PHE 221 221 221 PHE PHE A . n A 1 222 LYS 222 222 222 LYS LYS A . n A 1 223 ASN 223 223 223 ASN ASN A . n A 1 224 MET 224 224 224 MET MET A . n A 1 225 LEU 225 225 225 LEU LEU A . n A 1 226 ILE 226 226 226 ILE ILE A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 ARG 228 228 228 ARG ARG A . n A 1 229 THR 229 229 229 THR THR A . n A 1 230 HIS 230 230 230 HIS HIS A . n A 1 231 TYR 231 231 231 TYR TYR A . n A 1 232 SER 232 232 232 SER SER A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 LYS 234 234 234 LYS LYS A . n A 1 235 LYS 235 235 235 LYS LYS A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 ALA 238 238 238 ALA ALA A . n A 1 239 GLN 239 239 239 GLN GLN A . n A 1 240 GLN 240 240 240 GLN GLN A . n A 1 241 ARG 241 241 241 ARG ARG A . n A 1 242 GLN 242 242 242 GLN GLN A . n A 1 243 LEU 243 243 243 LEU LEU A . n A 1 244 GLU 244 244 244 GLU GLU A . n A 1 245 PHE 245 245 245 PHE PHE A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 TRP 247 247 247 TRP TRP A . n A 1 248 ARG 248 248 248 ARG ARG A . n A 1 249 GLN 249 249 249 GLN GLN A . n A 1 250 ILE 250 250 250 ILE ILE A . n A 1 251 TRP 251 251 251 TRP TRP A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 GLY 255 255 255 GLY GLY A . n A 1 256 ASP 256 256 256 ASP ASP A . n A 1 257 THR 257 257 257 THR THR A . n A 1 258 ALA 258 258 258 ALA ALA A . n A 1 259 LEU 259 259 259 LEU LEU A . n A 1 260 PHE 260 260 260 PHE PHE A . n A 1 261 THR 261 261 261 THR THR A . n A 1 262 HIS 262 262 262 HIS HIS A . n A 1 263 MET 263 263 263 MET MET A . n A 1 264 MET 264 264 264 MET MET A . n A 1 265 PRO 265 265 265 PRO PRO A . n A 1 266 PHE 266 266 266 PHE PHE A . n A 1 267 TYR 267 267 267 TYR TYR A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 TYR 269 269 269 TYR TYR A . n A 1 270 ASP 270 270 270 ASP ASP A . n A 1 271 ILE 271 271 271 ILE ILE A . n A 1 272 PRO 272 272 272 PRO PRO A . n A 1 273 HIS 273 273 273 HIS HIS A . n A 1 274 THR 274 274 274 THR THR A . n A 1 275 CYS 275 275 275 CYS CYS A . n A 1 276 GLY 276 276 276 GLY GLY A . n A 1 277 PRO 277 277 277 PRO PRO A . n A 1 278 ASP 278 278 278 ASP ASP A . n A 1 279 PRO 279 279 279 PRO PRO A . n A 1 280 LYS 280 280 280 LYS LYS A . n A 1 281 VAL 281 281 281 VAL VAL A . n A 1 282 CYS 282 282 282 CYS CYS A . n A 1 283 CYS 283 283 283 CYS CYS A . n A 1 284 GLN 284 284 284 GLN GLN A . n A 1 285 PHE 285 285 285 PHE PHE A . n A 1 286 ASP 286 286 286 ASP ASP A . n A 1 287 PHE 287 287 287 PHE PHE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 ARG 289 289 289 ARG ARG A . n A 1 290 MET 290 290 290 MET MET A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 SER 292 292 292 SER SER A . n A 1 293 PHE 293 293 293 PHE PHE A . n A 1 294 GLY 294 294 294 GLY GLY A . n A 1 295 LEU 295 295 295 LEU LEU A . n A 1 296 SER 296 296 296 SER SER A . n A 1 297 CYS 297 297 297 CYS CYS A . n A 1 298 PRO 298 298 298 PRO PRO A . n A 1 299 TRP 299 299 299 TRP TRP A . n A 1 300 LYS 300 300 300 LYS LYS A . n A 1 301 VAL 301 301 301 VAL VAL A . n A 1 302 PRO 302 302 302 PRO PRO A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ARG 304 304 304 ARG ARG A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 ILE 306 306 306 ILE ILE A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 ASP 308 308 308 ASP ASP A . n A 1 309 GLN 309 309 309 GLN GLN A . n A 1 310 ASN 310 310 310 ASN ASN A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 ALA 313 313 313 ALA ALA A . n A 1 314 ARG 314 314 314 ARG ARG A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASP 316 316 316 ASP ASP A . n A 1 317 LEU 317 317 317 LEU LEU A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 GLN 321 321 321 GLN GLN A . n A 1 322 TRP 322 322 322 TRP TRP A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LYS 325 325 325 LYS LYS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 GLU 327 327 327 GLU GLU A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 TYR 329 329 329 TYR TYR A . n A 1 330 ARG 330 330 330 ARG ARG A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 ASN 332 332 332 ASN ASN A . n A 1 333 VAL 333 333 333 VAL VAL A . n A 1 334 LEU 334 334 334 LEU LEU A . n A 1 335 LEU 335 335 335 LEU LEU A . n A 1 336 ILE 336 336 336 ILE ILE A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 LEU 338 338 338 LEU LEU A . n A 1 339 GLY 339 339 339 GLY GLY A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASN 341 341 341 ASN ASN A . n A 1 342 PHE 342 342 342 PHE PHE A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLN 346 346 346 GLN GLN A . n A 1 347 ASN 347 347 347 ASN ASN A . n A 1 348 THR 348 348 348 THR THR A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 TRP 350 350 350 TRP TRP A . n A 1 351 ASP 351 351 351 ASP ASP A . n A 1 352 VAL 352 352 352 VAL VAL A . n A 1 353 GLN 353 353 353 GLN GLN A . n A 1 354 ARG 354 354 354 ARG ARG A . n A 1 355 VAL 355 355 355 VAL VAL A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 TYR 357 357 357 TYR TYR A . n A 1 358 GLU 358 358 358 GLU GLU A . n A 1 359 ARG 359 359 359 ARG ARG A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 PHE 361 361 361 PHE PHE A . n A 1 362 GLU 362 362 362 GLU GLU A . n A 1 363 HIS 363 363 363 HIS HIS A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 SER 366 366 366 SER SER A . n A 1 367 GLN 367 367 367 GLN GLN A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 HIS 369 369 369 HIS HIS A . n A 1 370 PHE 370 370 370 PHE PHE A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 VAL 372 372 372 VAL VAL A . n A 1 373 GLN 373 373 373 GLN GLN A . n A 1 374 ALA 374 374 374 ALA ALA A . n A 1 375 GLN 375 375 375 GLN GLN A . n A 1 376 PHE 376 376 376 PHE PHE A . n A 1 377 GLY 377 377 377 GLY GLY A . n A 1 378 THR 378 378 378 THR THR A . n A 1 379 LEU 379 379 379 LEU LEU A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 GLU 381 381 381 GLU GLU A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 PHE 383 383 383 PHE PHE A . n A 1 384 ASP 384 384 384 ASP ASP A . n A 1 385 ALA 385 385 385 ALA ALA A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 HIS 387 387 387 HIS HIS A . n A 1 388 GLN 388 388 388 GLN GLN A . n A 1 389 ALA 389 389 389 ALA ALA A . n A 1 390 GLU 390 390 390 GLU GLU A . n A 1 391 ARG 391 391 391 ARG ARG A . n A 1 392 ALA 392 392 392 ALA ALA A . n A 1 393 GLY 393 393 393 GLY GLY A . n A 1 394 GLN 394 394 394 GLN GLN A . n A 1 395 ALA 395 395 395 ALA ALA A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PHE 397 397 397 PHE PHE A . n A 1 398 PRO 398 398 398 PRO PRO A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 SER 401 401 401 SER SER A . n A 1 402 GLY 402 402 402 GLY GLY A . n A 1 403 ASP 403 403 403 ASP ASP A . n A 1 404 PHE 404 404 404 PHE PHE A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 TYR 407 407 407 TYR TYR A . n A 1 408 ALA 408 408 408 ALA ALA A . n A 1 409 ASP 409 409 409 ASP ASP A . n A 1 410 ARG 410 410 410 ARG ARG A . n A 1 411 SER 411 411 411 SER SER A . n A 1 412 ASP 412 412 412 ASP ASP A . n A 1 413 ASN 413 413 413 ASN ASN A . n A 1 414 TYR 414 414 414 TYR TYR A . n A 1 415 TRP 415 415 415 TRP TRP A . n A 1 416 SER 416 416 416 SER SER A . n A 1 417 GLY 417 417 417 GLY GLY A . n A 1 418 TYR 418 418 418 TYR TYR A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 THR 420 420 420 THR THR A . n A 1 421 SER 421 421 421 SER SER A . n A 1 422 ARG 422 422 422 ARG ARG A . n A 1 423 PRO 423 423 423 PRO PRO A . n A 1 424 TYR 424 424 424 TYR TYR A . n A 1 425 HIS 425 425 425 HIS HIS A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 ARG 427 427 427 ARG ARG A . n A 1 428 MET 428 428 428 MET MET A . n A 1 429 ASP 429 429 429 ASP ASP A . n A 1 430 ARG 430 430 430 ARG ARG A . n A 1 431 VAL 431 431 431 VAL VAL A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 MET 433 433 433 MET MET A . n A 1 434 HIS 434 434 434 HIS HIS A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 ARG 437 437 437 ARG ARG A . n A 1 438 ALA 438 438 438 ALA ALA A . n A 1 439 ALA 439 439 439 ALA ALA A . n A 1 440 GLU 440 440 440 GLU GLU A . n A 1 441 MET 441 441 441 MET MET A . n A 1 442 LEU 442 442 442 LEU LEU A . n A 1 443 SER 443 443 443 SER SER A . n A 1 444 ALA 444 444 444 ALA ALA A . n A 1 445 TRP 445 445 445 TRP TRP A . n A 1 446 HIS 446 446 446 HIS HIS A . n A 1 447 SER 447 447 447 SER SER A . n A 1 448 TRP 448 448 448 TRP TRP A . n A 1 449 ASP 449 449 449 ASP ASP A . n A 1 450 GLY 450 450 450 GLY GLY A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ALA 452 452 452 ALA ALA A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 GLU 455 455 455 GLU GLU A . n A 1 456 GLU 456 456 456 GLU GLU A . n A 1 457 ARG 457 457 457 ARG ARG A . n A 1 458 LEU 458 458 458 LEU LEU A . n A 1 459 GLU 459 459 459 GLU GLU A . n A 1 460 GLN 460 460 460 GLN GLN A . n A 1 461 ALA 461 461 461 ALA ALA A . n A 1 462 ARG 462 462 462 ARG ARG A . n A 1 463 ARG 463 463 463 ARG ARG A . n A 1 464 GLU 464 464 464 GLU GLU A . n A 1 465 LEU 465 465 465 LEU LEU A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 GLN 469 469 469 GLN GLN A . n A 1 470 HIS 470 470 470 HIS HIS A . n A 1 471 HIS 471 471 471 HIS HIS A . n A 1 472 ASP 472 472 472 ASP ASP A . n A 1 473 GLY 473 473 473 GLY GLY A . n A 1 474 ILE 474 474 474 ILE ILE A . n A 1 475 THR 475 475 475 THR THR A . n A 1 476 GLY 476 476 476 GLY GLY A . n A 1 477 THR 477 477 477 THR THR A . n A 1 478 ALA 478 478 478 ALA ALA A . n A 1 479 LYS 479 479 479 LYS LYS A . n A 1 480 THR 480 480 480 THR THR A . n A 1 481 HIS 481 481 481 HIS HIS A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 VAL 483 483 483 VAL VAL A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 TYR 486 486 486 TYR TYR A . n A 1 487 GLU 487 487 487 GLU GLU A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 ARG 489 489 489 ARG ARG A . n A 1 490 MET 490 490 490 MET MET A . n A 1 491 GLN 491 491 491 GLN GLN A . n A 1 492 GLU 492 492 492 GLU GLU A . n A 1 493 ALA 493 493 493 ALA ALA A . n A 1 494 LEU 494 494 494 LEU LEU A . n A 1 495 LYS 495 495 495 LYS LYS A . n A 1 496 ALA 496 496 496 ALA ALA A . n A 1 497 CYS 497 497 497 CYS CYS A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 MET 499 499 499 MET MET A . n A 1 500 VAL 500 500 500 VAL VAL A . n A 1 501 MET 501 501 501 MET MET A . n A 1 502 GLN 502 502 502 GLN GLN A . n A 1 503 GLN 503 503 503 GLN GLN A . n A 1 504 SER 504 504 504 SER SER A . n A 1 505 VAL 505 505 505 VAL VAL A . n A 1 506 TYR 506 506 506 TYR TYR A . n A 1 507 ARG 507 507 507 ARG ARG A . n A 1 508 LEU 508 508 508 LEU LEU A . n A 1 509 LEU 509 509 509 LEU LEU A . n A 1 510 THR 510 510 510 THR THR A . n A 1 511 LYS 511 511 511 LYS LYS A . n A 1 512 PRO 512 512 512 PRO PRO A . n A 1 513 SER 513 513 513 SER SER A . n A 1 514 ILE 514 514 514 ILE ILE A . n A 1 515 TYR 515 515 515 TYR TYR A . n A 1 516 SER 516 516 516 SER SER A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASP 518 518 518 ASP ASP A . n A 1 519 PHE 519 519 519 PHE PHE A . n A 1 520 SER 520 520 520 SER SER A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 SER 522 522 522 SER SER A . n A 1 523 TYR 523 523 523 TYR TYR A . n A 1 524 PHE 524 524 524 PHE PHE A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 LEU 526 526 526 LEU LEU A . n A 1 527 ASP 527 527 527 ASP ASP A . n A 1 528 ASP 528 528 528 ASP ASP A . n A 1 529 SER 529 529 529 SER SER A . n A 1 530 ARG 530 530 530 ARG ARG A . n A 1 531 TRP 531 531 531 TRP TRP A . n A 1 532 PRO 532 532 532 PRO PRO A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 SER 534 534 534 SER SER A . n A 1 535 GLY 535 535 535 GLY GLY A . n A 1 536 VAL 536 536 536 VAL VAL A . n A 1 537 GLU 537 537 537 GLU GLU A . n A 1 538 ASP 538 538 538 ASP ASP A . n A 1 539 SER 539 539 539 SER SER A . n A 1 540 ARG 540 540 540 ARG ARG A . n A 1 541 THR 541 541 541 THR THR A . n A 1 542 THR 542 542 542 THR THR A . n A 1 543 ILE 543 543 543 ILE ILE A . n A 1 544 ILE 544 544 544 ILE ILE A . n A 1 545 LEU 545 545 545 LEU LEU A . n A 1 546 GLY 546 546 546 GLY GLY A . n A 1 547 GLU 547 547 547 GLU GLU A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ILE 549 549 549 ILE ILE A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 PRO 551 551 551 PRO PRO A . n A 1 552 SER 552 552 552 SER SER A . n A 1 553 LYS 553 553 553 LYS LYS A . n A 1 554 HIS 554 554 554 HIS HIS A . n A 1 555 VAL 555 555 555 VAL VAL A . n A 1 556 VAL 556 556 556 VAL VAL A . n A 1 557 MET 557 557 557 MET MET A . n A 1 558 HIS 558 558 558 HIS HIS A . n A 1 559 ASN 559 559 559 ASN ASN A . n A 1 560 THR 560 560 560 THR THR A . n A 1 561 LEU 561 561 561 LEU LEU A . n A 1 562 PRO 562 562 562 PRO PRO A . n A 1 563 HIS 563 563 563 HIS HIS A . n A 1 564 TRP 564 564 564 TRP TRP A . n A 1 565 ARG 565 565 565 ARG ARG A . n A 1 566 GLU 566 566 566 GLU GLU A . n A 1 567 GLN 567 567 567 GLN GLN A . n A 1 568 LEU 568 568 568 LEU LEU A . n A 1 569 VAL 569 569 569 VAL VAL A . n A 1 570 ASP 570 570 570 ASP ASP A . n A 1 571 PHE 571 571 571 PHE PHE A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 VAL 573 573 573 VAL VAL A . n A 1 574 SER 574 574 574 SER SER A . n A 1 575 SER 575 575 575 SER SER A . n A 1 576 PRO 576 576 576 PRO PRO A . n A 1 577 PHE 577 577 577 PHE PHE A . n A 1 578 VAL 578 578 578 VAL VAL A . n A 1 579 SER 579 579 579 SER SER A . n A 1 580 VAL 580 580 580 VAL VAL A . n A 1 581 THR 581 581 581 THR THR A . n A 1 582 ASP 582 582 582 ASP ASP A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 ALA 584 584 584 ALA ALA A . n A 1 585 ASN 585 585 585 ASN ASN A . n A 1 586 ASN 586 586 586 ASN ASN A . n A 1 587 PRO 587 587 587 PRO PRO A . n A 1 588 VAL 588 588 588 VAL VAL A . n A 1 589 GLU 589 589 589 GLU GLU A . n A 1 590 ALA 590 590 590 ALA ALA A . n A 1 591 GLN 591 591 591 GLN GLN A . n A 1 592 VAL 592 592 592 VAL VAL A . n A 1 593 SER 593 593 593 SER SER A . n A 1 594 PRO 594 594 594 PRO PRO A . n A 1 595 VAL 595 595 595 VAL VAL A . n A 1 596 TRP 596 596 596 TRP TRP A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 TRP 598 598 598 TRP TRP A . n A 1 599 HIS 599 599 599 HIS HIS A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASP 601 601 601 ASP ASP A . n A 1 602 THR 602 602 602 THR THR A . n A 1 603 LEU 603 603 603 LEU LEU A . n A 1 604 THR 604 604 604 THR THR A . n A 1 605 LYS 605 605 605 LYS LYS A . n A 1 606 THR 606 606 606 THR THR A . n A 1 607 ILE 607 607 607 ILE ILE A . n A 1 608 HIS 608 608 608 HIS HIS A . n A 1 609 PRO 609 609 609 PRO PRO A . n A 1 610 GLN 610 610 610 GLN GLN A . n A 1 611 GLY 611 611 611 GLY GLY A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 THR 613 613 613 THR THR A . n A 1 614 THR 614 614 614 THR THR A . n A 1 615 LYS 615 615 615 LYS LYS A . n A 1 616 TYR 616 616 616 TYR TYR A . n A 1 617 ARG 617 617 617 ARG ARG A . n A 1 618 ILE 618 618 618 ILE ILE A . n A 1 619 ILE 619 619 619 ILE ILE A . n A 1 620 PHE 620 620 620 PHE PHE A . n A 1 621 LYS 621 621 621 LYS LYS A . n A 1 622 ALA 622 622 622 ALA ALA A . n A 1 623 ARG 623 623 623 ARG ARG A . n A 1 624 VAL 624 624 624 VAL VAL A . n A 1 625 PRO 625 625 625 PRO PRO A . n A 1 626 PRO 626 626 626 PRO PRO A . n A 1 627 MET 627 627 627 MET MET A . n A 1 628 GLY 628 628 628 GLY GLY A . n A 1 629 LEU 629 629 629 LEU LEU A . n A 1 630 ALA 630 630 630 ALA ALA A . n A 1 631 THR 631 631 631 THR THR A . n A 1 632 TYR 632 632 632 TYR TYR A . n A 1 633 VAL 633 633 633 VAL VAL A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 THR 635 635 635 THR THR A . n A 1 636 ILE 636 636 636 ILE ILE A . n A 1 637 SER 637 637 637 SER SER A . n A 1 638 ASP 638 638 638 ASP ASP A . n A 1 639 SER 639 639 639 SER SER A . n A 1 640 LYS 640 640 640 LYS LYS A . n A 1 641 PRO 641 641 641 PRO PRO A . n A 1 642 GLU 642 642 642 GLU GLU A . n A 1 643 HIS 643 643 643 HIS HIS A . n A 1 644 THR 644 644 644 THR THR A . n A 1 645 SER 645 645 645 SER SER A . n A 1 646 TYR 646 646 646 TYR TYR A . n A 1 647 ALA 647 647 647 ALA ALA A . n A 1 648 SER 648 648 648 SER SER A . n A 1 649 ASN 649 649 649 ASN ASN A . n A 1 650 LEU 650 650 650 LEU LEU A . n A 1 651 LEU 651 651 651 LEU LEU A . n A 1 652 LEU 652 652 652 LEU LEU A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 LYS 654 654 654 LYS LYS A . n A 1 655 ASN 655 655 655 ASN ASN A . n A 1 656 PRO 656 656 656 PRO PRO A . n A 1 657 THR 657 657 657 THR THR A . n A 1 658 SER 658 658 658 SER SER A . n A 1 659 LEU 659 659 659 LEU LEU A . n A 1 660 PRO 660 660 660 PRO PRO A . n A 1 661 LEU 661 661 661 LEU LEU A . n A 1 662 GLY 662 662 662 GLY GLY A . n A 1 663 GLN 663 663 663 GLN GLN A . n A 1 664 TYR 664 664 664 TYR TYR A . n A 1 665 PRO 665 665 665 PRO PRO A . n A 1 666 GLU 666 666 666 GLU GLU A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 LYS 669 669 669 LYS LYS A . n A 1 670 PHE 670 670 670 PHE PHE A . n A 1 671 GLY 671 671 671 GLY GLY A . n A 1 672 ASP 672 672 672 ASP ASP A . n A 1 673 PRO 673 673 673 PRO PRO A . n A 1 674 ARG 674 674 674 ARG ARG A . n A 1 675 GLU 675 675 675 GLU GLU A . n A 1 676 ILE 676 676 676 ILE ILE A . n A 1 677 SER 677 677 677 SER SER A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 ARG 679 679 679 ARG ARG A . n A 1 680 VAL 680 680 680 VAL VAL A . n A 1 681 GLY 681 681 681 GLY GLY A . n A 1 682 ASN 682 682 682 ASN ASN A . n A 1 683 GLY 683 683 683 GLY GLY A . n A 1 684 PRO 684 684 684 PRO PRO A . n A 1 685 THR 685 685 685 THR THR A . n A 1 686 LEU 686 686 686 LEU LEU A . n A 1 687 ALA 687 687 687 ALA ALA A . n A 1 688 PHE 688 688 688 PHE PHE A . n A 1 689 SER 689 689 689 SER SER A . n A 1 690 GLU 690 690 690 GLU GLU A . n A 1 691 GLN 691 691 691 GLN GLN A . n A 1 692 GLY 692 692 692 GLY GLY A . n A 1 693 LEU 693 693 693 LEU LEU A . n A 1 694 LEU 694 694 694 LEU LEU A . n A 1 695 LYS 695 695 695 LYS LYS A . n A 1 696 SER 696 696 696 SER SER A . n A 1 697 ILE 697 697 697 ILE ILE A . n A 1 698 GLN 698 698 698 GLN GLN A . n A 1 699 LEU 699 699 699 LEU LEU A . n A 1 700 THR 700 700 700 THR THR A . n A 1 701 GLN 701 701 701 GLN GLN A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 SER 703 703 703 SER SER A . n A 1 704 PRO 704 704 704 PRO PRO A . n A 1 705 HIS 705 705 705 HIS HIS A . n A 1 706 VAL 706 706 706 VAL VAL A . n A 1 707 PRO 707 707 707 PRO PRO A . n A 1 708 VAL 708 708 708 VAL VAL A . n A 1 709 HIS 709 709 709 HIS HIS A . n A 1 710 PHE 710 710 710 PHE PHE A . n A 1 711 LYS 711 711 711 LYS LYS A . n A 1 712 PHE 712 712 712 PHE PHE A . n A 1 713 LEU 713 713 713 LEU LEU A . n A 1 714 LYS 714 714 714 LYS LYS A . n A 1 715 TYR 715 715 715 TYR TYR A . n A 1 716 GLY 716 716 716 GLY GLY A . n A 1 717 VAL 717 717 717 VAL VAL A . n A 1 718 ARG 718 718 718 ARG ARG A . n A 1 719 SER 719 719 719 SER SER A . n A 1 720 HIS 720 720 720 HIS HIS A . n A 1 721 GLY 721 721 721 GLY GLY A . n A 1 722 ASP 722 722 722 ASP ASP A . n A 1 723 ARG 723 723 723 ARG ARG A . n A 1 724 SER 724 724 724 SER SER A . n A 1 725 GLY 725 725 725 GLY GLY A . n A 1 726 ALA 726 726 726 ALA ALA A . n A 1 727 TYR 727 727 727 TYR TYR A . n A 1 728 LEU 728 728 728 LEU LEU A . n A 1 729 PHE 729 729 729 PHE PHE A . n A 1 730 LEU 730 730 730 LEU LEU A . n A 1 731 PRO 731 731 731 PRO PRO A . n A 1 732 ASN 732 732 732 ASN ASN A . n A 1 733 GLY 733 733 733 GLY GLY A . n A 1 734 PRO 734 734 734 PRO PRO A . n A 1 735 ALA 735 735 735 ALA ALA A . n A 1 736 SER 736 736 736 SER SER A . n A 1 737 PRO 737 737 737 PRO PRO A . n A 1 738 VAL 738 738 738 VAL VAL A . n A 1 739 GLU 739 739 739 GLU GLU A . n A 1 740 LEU 740 740 740 LEU LEU A . n A 1 741 GLY 741 741 741 GLY GLY A . n A 1 742 GLN 742 742 742 GLN GLN A . n A 1 743 PRO 743 743 743 PRO PRO A . n A 1 744 VAL 744 744 744 VAL VAL A . n A 1 745 VAL 745 745 745 VAL VAL A . n A 1 746 LEU 746 746 746 LEU LEU A . n A 1 747 VAL 747 747 747 VAL VAL A . n A 1 748 THR 748 748 748 THR THR A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 GLY 750 750 750 GLY GLY A . n A 1 751 LYS 751 751 751 LYS LYS A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLU 753 753 753 GLU GLU A . n A 1 754 SER 754 754 754 SER SER A . n A 1 755 SER 755 755 755 SER SER A . n A 1 756 VAL 756 756 756 VAL VAL A . n A 1 757 SER 757 757 757 SER SER A . n A 1 758 VAL 758 758 758 VAL VAL A . n A 1 759 GLY 759 759 759 GLY GLY A . n A 1 760 LEU 760 760 760 LEU LEU A . n A 1 761 PRO 761 761 761 PRO PRO A . n A 1 762 SER 762 762 762 SER SER A . n A 1 763 VAL 763 763 763 VAL VAL A . n A 1 764 VAL 764 764 764 VAL VAL A . n A 1 765 HIS 765 765 765 HIS HIS A . n A 1 766 GLN 766 766 766 GLN GLN A . n A 1 767 THR 767 767 767 THR THR A . n A 1 768 ILE 768 768 768 ILE ILE A . n A 1 769 MET 769 769 769 MET MET A . n A 1 770 ARG 770 770 770 ARG ARG A . n A 1 771 GLY 771 771 771 GLY GLY A . n A 1 772 GLY 772 772 772 GLY GLY A . n A 1 773 ALA 773 773 773 ALA ALA A . n A 1 774 PRO 774 774 774 PRO PRO A . n A 1 775 GLU 775 775 775 GLU GLU A . n A 1 776 ILE 776 776 776 ILE ILE A . n A 1 777 ARG 777 777 777 ARG ARG A . n A 1 778 ASN 778 778 778 ASN ASN A . n A 1 779 LEU 779 779 779 LEU LEU A . n A 1 780 VAL 780 780 780 VAL VAL A . n A 1 781 ASP 781 781 781 ASP ASP A . n A 1 782 ILE 782 782 782 ILE ILE A . n A 1 783 GLY 783 783 783 GLY GLY A . n A 1 784 SER 784 784 784 SER SER A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 ASP 786 786 786 ASP ASP A . n A 1 787 ASN 787 787 787 ASN ASN A . n A 1 788 THR 788 788 788 THR THR A . n A 1 789 GLU 789 789 789 GLU GLU A . n A 1 790 ILE 790 790 790 ILE ILE A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 MET 792 792 792 MET MET A . n A 1 793 ARG 793 793 793 ARG ARG A . n A 1 794 LEU 794 794 794 LEU LEU A . n A 1 795 GLU 795 795 795 GLU GLU A . n A 1 796 THR 796 796 796 THR THR A . n A 1 797 HIS 797 797 797 HIS HIS A . n A 1 798 ILE 798 798 798 ILE ILE A . n A 1 799 ASP 799 799 799 ASP ASP A . n A 1 800 SER 800 800 800 SER SER A . n A 1 801 GLY 801 801 801 GLY GLY A . n A 1 802 ASP 802 802 802 ASP ASP A . n A 1 803 ILE 803 803 803 ILE ILE A . n A 1 804 PHE 804 804 804 PHE PHE A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 THR 806 806 806 THR THR A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 LEU 808 808 808 LEU LEU A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 GLY 810 810 810 GLY GLY A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 GLN 812 812 812 GLN GLN A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ILE 814 814 814 ILE ILE A . n A 1 815 LYS 815 815 815 LYS LYS A . n A 1 816 ARG 816 816 816 ARG ARG A . n A 1 817 ARG 817 817 817 ARG ARG A . n A 1 818 ARG 818 818 818 ARG ARG A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 ASP 820 820 820 ASP ASP A . n A 1 821 LYS 821 821 821 LYS LYS A . n A 1 822 LEU 822 822 822 LEU LEU A . n A 1 823 PRO 823 823 823 PRO PRO A . n A 1 824 LEU 824 824 824 LEU LEU A . n A 1 825 GLN 825 825 825 GLN GLN A . n A 1 826 ALA 826 826 826 ALA ALA A . n A 1 827 ASN 827 827 827 ASN ASN A . n A 1 828 TYR 828 828 828 TYR TYR A . n A 1 829 TYR 829 829 829 TYR TYR A . n A 1 830 PRO 830 830 830 PRO PRO A . n A 1 831 ILE 831 831 831 ILE ILE A . n A 1 832 PRO 832 832 832 PRO PRO A . n A 1 833 SER 833 833 833 SER SER A . n A 1 834 GLY 834 834 834 GLY GLY A . n A 1 835 MET 835 835 835 MET MET A . n A 1 836 PHE 836 836 836 PHE PHE A . n A 1 837 ILE 837 837 837 ILE ILE A . n A 1 838 GLU 838 838 838 GLU GLU A . n A 1 839 ASP 839 839 839 ASP ASP A . n A 1 840 ALA 840 840 840 ALA ALA A . n A 1 841 ASN 841 841 841 ASN ASN A . n A 1 842 THR 842 842 842 THR THR A . n A 1 843 ARG 843 843 843 ARG ARG A . n A 1 844 LEU 844 844 844 LEU LEU A . n A 1 845 THR 845 845 845 THR THR A . n A 1 846 LEU 846 846 846 LEU LEU A . n A 1 847 LEU 847 847 847 LEU LEU A . n A 1 848 THR 848 848 848 THR THR A . n A 1 849 GLY 849 849 849 GLY GLY A . n A 1 850 GLN 850 850 850 GLN GLN A . n A 1 851 PRO 851 851 851 PRO PRO A . n A 1 852 LEU 852 852 852 LEU LEU A . n A 1 853 GLY 853 853 853 GLY GLY A . n A 1 854 GLY 854 854 854 GLY GLY A . n A 1 855 SER 855 855 855 SER SER A . n A 1 856 SER 856 856 856 SER SER A . n A 1 857 LEU 857 857 857 LEU LEU A . n A 1 858 ALA 858 858 858 ALA ALA A . n A 1 859 SER 859 859 859 SER SER A . n A 1 860 GLY 860 860 860 GLY GLY A . n A 1 861 GLU 861 861 861 GLU GLU A . n A 1 862 LEU 862 862 862 LEU LEU A . n A 1 863 GLU 863 863 863 GLU GLU A . n A 1 864 ILE 864 864 864 ILE ILE A . n A 1 865 MET 865 865 865 MET MET A . n A 1 866 GLN 866 866 866 GLN GLN A . n A 1 867 ASP 867 867 867 ASP ASP A . n A 1 868 ARG 868 868 868 ARG ARG A . n A 1 869 ARG 869 869 869 ARG ARG A . n A 1 870 LEU 870 870 870 LEU LEU A . n A 1 871 ALA 871 871 871 ALA ALA A . n A 1 872 SER 872 872 872 SER SER A . n A 1 873 ASP 873 873 873 ASP ASP A . n A 1 874 ASP 874 874 874 ASP ASP A . n A 1 875 GLU 875 875 875 GLU GLU A . n A 1 876 ARG 876 876 876 ARG ARG A . n A 1 877 GLY 877 877 877 GLY GLY A . n A 1 878 LEU 878 878 878 LEU LEU A . n A 1 879 GLY 879 879 879 GLY GLY A . n A 1 880 GLN 880 880 880 GLN GLN A . n A 1 881 GLY 881 881 881 GLY GLY A . n A 1 882 VAL 882 882 882 VAL VAL A . n A 1 883 LEU 883 883 883 LEU LEU A . n A 1 884 ASP 884 884 884 ASP ASP A . n A 1 885 ASN 885 885 885 ASN ASN A . n A 1 886 LYS 886 886 886 LYS LYS A . n A 1 887 PRO 887 887 887 PRO PRO A . n A 1 888 VAL 888 888 888 VAL VAL A . n A 1 889 LEU 889 889 889 LEU LEU A . n A 1 890 HIS 890 890 890 HIS HIS A . n A 1 891 ILE 891 891 891 ILE ILE A . n A 1 892 TYR 892 892 892 TYR TYR A . n A 1 893 ARG 893 893 893 ARG ARG A . n A 1 894 LEU 894 894 894 LEU LEU A . n A 1 895 VAL 895 895 895 VAL VAL A . n A 1 896 LEU 896 896 896 LEU LEU A . n A 1 897 GLU 897 897 897 GLU GLU A . n A 1 898 LYS 898 898 898 LYS LYS A . n A 1 899 VAL 899 899 899 VAL VAL A . n A 1 900 ASN 900 900 900 ASN ASN A . n A 1 901 ASN 901 901 901 ASN ASN A . n A 1 902 CYS 902 902 902 CYS CYS A . n A 1 903 VAL 903 903 903 VAL VAL A . n A 1 904 ARG 904 904 904 ARG ARG A . n A 1 905 PRO 905 905 905 PRO PRO A . n A 1 906 SER 906 906 906 SER SER A . n A 1 907 LYS 907 907 907 LYS LYS A . n A 1 908 LEU 908 908 908 LEU LEU A . n A 1 909 HIS 909 909 909 HIS HIS A . n A 1 910 PRO 910 910 910 PRO PRO A . n A 1 911 ALA 911 911 911 ALA ALA A . n A 1 912 GLY 912 912 912 GLY GLY A . n A 1 913 TYR 913 913 913 TYR TYR A . n A 1 914 LEU 914 914 914 LEU LEU A . n A 1 915 THR 915 915 915 THR THR A . n A 1 916 SER 916 916 916 SER SER A . n A 1 917 ALA 917 917 917 ALA ALA A . n A 1 918 ALA 918 918 918 ALA ALA A . n A 1 919 HIS 919 919 919 HIS HIS A . n A 1 920 LYS 920 920 920 LYS LYS A . n A 1 921 ALA 921 921 921 ALA ALA A . n A 1 922 SER 922 922 922 SER SER A . n A 1 923 GLN 923 923 923 GLN GLN A . n A 1 924 SER 924 924 924 SER SER A . n A 1 925 LEU 925 925 925 LEU LEU A . n A 1 926 LEU 926 926 926 LEU LEU A . n A 1 927 ASP 927 927 927 ASP ASP A . n A 1 928 PRO 928 928 928 PRO PRO A . n A 1 929 LEU 929 929 929 LEU LEU A . n A 1 930 ASP 930 930 930 ASP ASP A . n A 1 931 LYS 931 931 931 LYS LYS A . n A 1 932 PHE 932 932 932 PHE PHE A . n A 1 933 ILE 933 933 933 ILE ILE A . n A 1 934 PHE 934 934 934 PHE PHE A . n A 1 935 ALA 935 935 935 ALA ALA A . n A 1 936 GLU 936 936 936 GLU GLU A . n A 1 937 ASN 937 937 937 ASN ASN A . n A 1 938 GLU 938 938 938 GLU GLU A . n A 1 939 TRP 939 939 939 TRP TRP A . n A 1 940 ILE 940 940 940 ILE ILE A . n A 1 941 GLY 941 941 941 GLY GLY A . n A 1 942 ALA 942 942 942 ALA ALA A . n A 1 943 GLN 943 943 943 GLN GLN A . n A 1 944 GLY 944 944 944 GLY GLY A . n A 1 945 GLN 945 945 945 GLN GLN A . n A 1 946 PHE 946 946 946 PHE PHE A . n A 1 947 GLY 947 947 947 GLY GLY A . n A 1 948 GLY 948 948 948 GLY GLY A . n A 1 949 ASP 949 949 949 ASP ASP A . n A 1 950 HIS 950 950 950 HIS HIS A . n A 1 951 PRO 951 951 951 PRO PRO A . n A 1 952 SER 952 952 952 SER SER A . n A 1 953 ALA 953 953 953 ALA ALA A . n A 1 954 ARG 954 954 954 ARG ARG A . n A 1 955 GLU 955 955 955 GLU GLU A . n A 1 956 ASP 956 956 956 ASP ASP A . n A 1 957 LEU 957 957 957 LEU LEU A . n A 1 958 ASP 958 958 958 ASP ASP A . n A 1 959 VAL 959 959 959 VAL VAL A . n A 1 960 SER 960 960 960 SER SER A . n A 1 961 VAL 961 961 961 VAL VAL A . n A 1 962 MET 962 962 962 MET MET A . n A 1 963 ARG 963 963 963 ARG ARG A . n A 1 964 ARG 964 964 964 ARG ARG A . n A 1 965 LEU 965 965 965 LEU LEU A . n A 1 966 THR 966 966 966 THR THR A . n A 1 967 LYS 967 967 967 LYS LYS A . n A 1 968 SER 968 968 968 SER SER A . n A 1 969 SER 969 969 969 SER SER A . n A 1 970 ALA 970 970 970 ALA ALA A . n A 1 971 LYS 971 971 971 LYS LYS A . n A 1 972 THR 972 972 972 THR THR A . n A 1 973 GLN 973 973 973 GLN GLN A . n A 1 974 ARG 974 974 974 ARG ARG A . n A 1 975 VAL 975 975 975 VAL VAL A . n A 1 976 GLY 976 976 976 GLY GLY A . n A 1 977 TYR 977 977 977 TYR TYR A . n A 1 978 VAL 978 978 978 VAL VAL A . n A 1 979 LEU 979 979 979 LEU LEU A . n A 1 980 HIS 980 980 980 HIS HIS A . n A 1 981 ARG 981 981 981 ARG ARG A . n A 1 982 THR 982 982 982 THR THR A . n A 1 983 ASN 983 983 983 ASN ASN A . n A 1 984 LEU 984 984 984 LEU LEU A . n A 1 985 MET 985 985 985 MET MET A . n A 1 986 GLN 986 986 986 GLN GLN A . n A 1 987 CYS 987 987 987 CYS CYS A . n A 1 988 GLY 988 988 988 GLY GLY A . n A 1 989 THR 989 989 989 THR THR A . n A 1 990 PRO 990 990 990 PRO PRO A . n A 1 991 GLU 991 991 991 GLU GLU A . n A 1 992 GLU 992 992 992 GLU GLU A . n A 1 993 HIS 993 993 993 HIS HIS A . n A 1 994 THR 994 994 994 THR THR A . n A 1 995 GLN 995 995 995 GLN GLN A . n A 1 996 LYS 996 996 996 LYS LYS A . n A 1 997 LEU 997 997 997 LEU LEU A . n A 1 998 ASP 998 998 998 ASP ASP A . n A 1 999 VAL 999 999 999 VAL VAL A . n A 1 1000 CYS 1000 1000 1000 CYS CYS A . n A 1 1001 HIS 1001 1001 1001 HIS HIS A . n A 1 1002 LEU 1002 1002 1002 LEU LEU A . n A 1 1003 LEU 1003 1003 1003 LEU LEU A . n A 1 1004 PRO 1004 1004 1004 PRO PRO A . n A 1 1005 ASN 1005 1005 1005 ASN ASN A . n A 1 1006 VAL 1006 1006 1006 VAL VAL A . n A 1 1007 ALA 1007 1007 1007 ALA ALA A . n A 1 1008 ARG 1008 1008 1008 ARG ARG A . n A 1 1009 CYS 1009 1009 1009 CYS CYS A . n A 1 1010 GLU 1010 1010 1010 GLU GLU A . n A 1 1011 ARG 1011 1011 1011 ARG ARG A . n A 1 1012 THR 1012 1012 1012 THR THR A . n A 1 1013 THR 1013 1013 1013 THR THR A . n A 1 1014 LEU 1014 1014 1014 LEU LEU A . n A 1 1015 THR 1015 1015 1015 THR THR A . n A 1 1016 PHE 1016 1016 1016 PHE PHE A . n A 1 1017 LEU 1017 1017 1017 LEU LEU A . n A 1 1018 GLN 1018 1018 1018 GLN GLN A . n A 1 1019 ASN 1019 1019 1019 ASN ASN A . n A 1 1020 LEU 1020 1020 1020 LEU LEU A . n A 1 1021 GLU 1021 1021 1021 GLU GLU A . n A 1 1022 HIS 1022 1022 1022 HIS HIS A . n A 1 1023 LEU 1023 1023 1023 LEU LEU A . n A 1 1024 ASP 1024 1024 1024 ASP ASP A . n A 1 1025 GLY 1025 1025 1025 GLY GLY A . n A 1 1026 MET 1026 1026 1026 MET MET A . n A 1 1027 VAL 1027 1027 1027 VAL VAL A . n A 1 1028 ALA 1028 1028 1028 ALA ALA A . n A 1 1029 PRO 1029 1029 1029 PRO PRO A . n A 1 1030 GLU 1030 1030 1030 GLU GLU A . n A 1 1031 VAL 1031 1031 1031 VAL VAL A . n A 1 1032 CYS 1032 1032 1032 CYS CYS A . n A 1 1033 PRO 1033 1033 1033 PRO PRO A . n A 1 1034 MET 1034 1034 1034 MET MET A . n A 1 1035 GLU 1035 1035 1035 GLU GLU A . n A 1 1036 THR 1036 1036 1036 THR THR A . n A 1 1037 ALA 1037 1037 1037 ALA ALA A . n A 1 1038 ALA 1038 1038 1038 ALA ALA A . n A 1 1039 TYR 1039 1039 1039 TYR TYR A . n A 1 1040 VAL 1040 1040 1040 VAL VAL A . n A 1 1041 SER 1041 1041 1041 SER SER A . n A 1 1042 SER 1042 1042 1042 SER SER A . n A 1 1043 HIS 1043 1043 1043 HIS HIS A . n A 1 1044 SER 1044 1044 1044 SER SER A . n A 1 1045 SER 1045 1045 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 2001 2001 NAG NAG A . C 3 ZN 1 2004 2004 ZN ZN A . D 4 FMF 1 2003 2003 FMF FMF A . E 5 MPD 1 2002 2002 MPD MPD A . F 6 HOH 1 2005 1 HOH HOH A . F 6 HOH 2 2006 2 HOH HOH A . F 6 HOH 3 2007 3 HOH HOH A . F 6 HOH 4 2008 4 HOH HOH A . F 6 HOH 5 2009 5 HOH HOH A . F 6 HOH 6 2010 6 HOH HOH A . F 6 HOH 7 2011 7 HOH HOH A . F 6 HOH 8 2012 8 HOH HOH A . F 6 HOH 9 2013 9 HOH HOH A . F 6 HOH 10 2014 10 HOH HOH A . F 6 HOH 11 2015 11 HOH HOH A . F 6 HOH 12 2016 12 HOH HOH A . F 6 HOH 13 2017 13 HOH HOH A . F 6 HOH 14 2018 14 HOH HOH A . F 6 HOH 15 2019 15 HOH HOH A . F 6 HOH 16 2020 16 HOH HOH A . F 6 HOH 17 2021 17 HOH HOH A . F 6 HOH 18 2022 18 HOH HOH A . F 6 HOH 19 2023 19 HOH HOH A . F 6 HOH 20 2024 20 HOH HOH A . F 6 HOH 21 2025 21 HOH HOH A . F 6 HOH 22 2026 22 HOH HOH A . F 6 HOH 23 2027 23 HOH HOH A . F 6 HOH 24 2028 24 HOH HOH A . F 6 HOH 25 2029 25 HOH HOH A . F 6 HOH 26 2030 26 HOH HOH A . F 6 HOH 27 2031 27 HOH HOH A . F 6 HOH 28 2032 28 HOH HOH A . F 6 HOH 29 2033 29 HOH HOH A . F 6 HOH 30 2034 30 HOH HOH A . F 6 HOH 31 2035 31 HOH HOH A . F 6 HOH 32 2036 32 HOH HOH A . F 6 HOH 33 2037 33 HOH HOH A . F 6 HOH 34 2038 34 HOH HOH A . F 6 HOH 35 2039 35 HOH HOH A . F 6 HOH 36 2040 36 HOH HOH A . F 6 HOH 37 2041 37 HOH HOH A . F 6 HOH 38 2042 38 HOH HOH A . F 6 HOH 39 2043 39 HOH HOH A . F 6 HOH 40 2044 40 HOH HOH A . F 6 HOH 41 2045 41 HOH HOH A . F 6 HOH 42 2046 42 HOH HOH A . F 6 HOH 43 2047 43 HOH HOH A . F 6 HOH 44 2048 44 HOH HOH A . F 6 HOH 45 2049 45 HOH HOH A . F 6 HOH 46 2050 46 HOH HOH A . F 6 HOH 47 2051 47 HOH HOH A . F 6 HOH 48 2052 48 HOH HOH A . F 6 HOH 49 2053 49 HOH HOH A . F 6 HOH 50 2054 50 HOH HOH A . F 6 HOH 51 2055 51 HOH HOH A . F 6 HOH 52 2056 52 HOH HOH A . F 6 HOH 53 2057 53 HOH HOH A . F 6 HOH 54 2058 54 HOH HOH A . F 6 HOH 55 2059 55 HOH HOH A . F 6 HOH 56 2060 56 HOH HOH A . F 6 HOH 57 2061 57 HOH HOH A . F 6 HOH 58 2062 58 HOH HOH A . F 6 HOH 59 2063 59 HOH HOH A . F 6 HOH 60 2064 60 HOH HOH A . F 6 HOH 61 2065 61 HOH HOH A . F 6 HOH 62 2066 62 HOH HOH A . F 6 HOH 63 2067 63 HOH HOH A . F 6 HOH 64 2068 64 HOH HOH A . F 6 HOH 65 2069 65 HOH HOH A . F 6 HOH 66 2070 66 HOH HOH A . F 6 HOH 67 2071 67 HOH HOH A . F 6 HOH 68 2072 68 HOH HOH A . F 6 HOH 69 2073 69 HOH HOH A . F 6 HOH 70 2074 70 HOH HOH A . F 6 HOH 71 2075 71 HOH HOH A . F 6 HOH 72 2076 72 HOH HOH A . F 6 HOH 73 2077 73 HOH HOH A . F 6 HOH 74 2078 74 HOH HOH A . F 6 HOH 75 2079 75 HOH HOH A . F 6 HOH 76 2080 76 HOH HOH A . F 6 HOH 77 2081 77 HOH HOH A . F 6 HOH 78 2082 78 HOH HOH A . F 6 HOH 79 2083 79 HOH HOH A . F 6 HOH 80 2084 80 HOH HOH A . F 6 HOH 81 2085 81 HOH HOH A . F 6 HOH 82 2086 82 HOH HOH A . F 6 HOH 83 2087 83 HOH HOH A . F 6 HOH 84 2088 84 HOH HOH A . F 6 HOH 85 2089 85 HOH HOH A . F 6 HOH 86 2090 86 HOH HOH A . F 6 HOH 87 2091 87 HOH HOH A . F 6 HOH 88 2092 88 HOH HOH A . F 6 HOH 89 2093 89 HOH HOH A . F 6 HOH 90 2094 90 HOH HOH A . F 6 HOH 91 2095 91 HOH HOH A . F 6 HOH 92 2096 92 HOH HOH A . F 6 HOH 93 2097 93 HOH HOH A . F 6 HOH 94 2098 94 HOH HOH A . F 6 HOH 95 2099 95 HOH HOH A . F 6 HOH 96 2100 96 HOH HOH A . F 6 HOH 97 2101 97 HOH HOH A . F 6 HOH 98 2102 98 HOH HOH A . F 6 HOH 99 2103 99 HOH HOH A . F 6 HOH 100 2104 100 HOH HOH A . F 6 HOH 101 2105 101 HOH HOH A . F 6 HOH 102 2106 102 HOH HOH A . F 6 HOH 103 2107 103 HOH HOH A . F 6 HOH 104 2108 104 HOH HOH A . F 6 HOH 105 2109 105 HOH HOH A . F 6 HOH 106 2110 106 HOH HOH A . F 6 HOH 107 2111 107 HOH HOH A . F 6 HOH 108 2112 108 HOH HOH A . F 6 HOH 109 2113 109 HOH HOH A . F 6 HOH 110 2114 110 HOH HOH A . F 6 HOH 111 2115 111 HOH HOH A . F 6 HOH 112 2116 112 HOH HOH A . F 6 HOH 113 2117 113 HOH HOH A . F 6 HOH 114 2118 114 HOH HOH A . F 6 HOH 115 2119 115 HOH HOH A . F 6 HOH 116 2120 116 HOH HOH A . F 6 HOH 117 2121 117 HOH HOH A . F 6 HOH 118 2122 118 HOH HOH A . F 6 HOH 119 2123 119 HOH HOH A . F 6 HOH 120 2124 120 HOH HOH A . F 6 HOH 121 2125 121 HOH HOH A . F 6 HOH 122 2126 122 HOH HOH A . F 6 HOH 123 2127 123 HOH HOH A . F 6 HOH 124 2128 124 HOH HOH A . F 6 HOH 125 2129 125 HOH HOH A . F 6 HOH 126 2130 126 HOH HOH A . F 6 HOH 127 2131 127 HOH HOH A . F 6 HOH 128 2132 128 HOH HOH A . F 6 HOH 129 2133 129 HOH HOH A . F 6 HOH 130 2134 130 HOH HOH A . F 6 HOH 131 2135 131 HOH HOH A . F 6 HOH 132 2136 132 HOH HOH A . F 6 HOH 133 2137 133 HOH HOH A . F 6 HOH 134 2138 134 HOH HOH A . F 6 HOH 135 2139 135 HOH HOH A . F 6 HOH 136 2140 136 HOH HOH A . F 6 HOH 137 2141 137 HOH HOH A . F 6 HOH 138 2142 138 HOH HOH A . F 6 HOH 139 2143 139 HOH HOH A . F 6 HOH 140 2144 140 HOH HOH A . F 6 HOH 141 2145 141 HOH HOH A . F 6 HOH 142 2146 142 HOH HOH A . F 6 HOH 143 2147 143 HOH HOH A . F 6 HOH 144 2148 144 HOH HOH A . F 6 HOH 145 2149 145 HOH HOH A . F 6 HOH 146 2150 146 HOH HOH A . F 6 HOH 147 2151 147 HOH HOH A . F 6 HOH 148 2152 148 HOH HOH A . F 6 HOH 149 2153 149 HOH HOH A . F 6 HOH 150 2154 150 HOH HOH A . F 6 HOH 151 2155 151 HOH HOH A . F 6 HOH 152 2156 152 HOH HOH A . F 6 HOH 153 2157 153 HOH HOH A . F 6 HOH 154 2158 154 HOH HOH A . F 6 HOH 155 2159 155 HOH HOH A . F 6 HOH 156 2160 156 HOH HOH A . F 6 HOH 157 2161 157 HOH HOH A . F 6 HOH 158 2162 158 HOH HOH A . F 6 HOH 159 2163 159 HOH HOH A . F 6 HOH 160 2164 160 HOH HOH A . F 6 HOH 161 2165 161 HOH HOH A . F 6 HOH 162 2166 162 HOH HOH A . F 6 HOH 163 2167 163 HOH HOH A . F 6 HOH 164 2168 164 HOH HOH A . F 6 HOH 165 2169 165 HOH HOH A . F 6 HOH 166 2170 166 HOH HOH A . F 6 HOH 167 2171 167 HOH HOH A . F 6 HOH 168 2172 168 HOH HOH A . F 6 HOH 169 2173 169 HOH HOH A . F 6 HOH 170 2174 170 HOH HOH A . F 6 HOH 171 2175 171 HOH HOH A . F 6 HOH 172 2176 172 HOH HOH A . F 6 HOH 173 2177 173 HOH HOH A . F 6 HOH 174 2178 174 HOH HOH A . F 6 HOH 175 2179 175 HOH HOH A . F 6 HOH 176 2180 176 HOH HOH A . F 6 HOH 177 2181 177 HOH HOH A . F 6 HOH 178 2182 178 HOH HOH A . F 6 HOH 179 2183 179 HOH HOH A . F 6 HOH 180 2184 180 HOH HOH A . F 6 HOH 181 2185 181 HOH HOH A . F 6 HOH 182 2186 182 HOH HOH A . F 6 HOH 183 2187 183 HOH HOH A . F 6 HOH 184 2188 184 HOH HOH A . F 6 HOH 185 2189 185 HOH HOH A . F 6 HOH 186 2190 186 HOH HOH A . F 6 HOH 187 2191 187 HOH HOH A . F 6 HOH 188 2192 188 HOH HOH A . F 6 HOH 189 2193 189 HOH HOH A . F 6 HOH 190 2194 190 HOH HOH A . F 6 HOH 191 2195 191 HOH HOH A . F 6 HOH 192 2196 192 HOH HOH A . F 6 HOH 193 2197 193 HOH HOH A . F 6 HOH 194 2198 194 HOH HOH A . F 6 HOH 195 2199 195 HOH HOH A . F 6 HOH 196 2200 196 HOH HOH A . F 6 HOH 197 2201 197 HOH HOH A . F 6 HOH 198 2202 198 HOH HOH A . F 6 HOH 199 2203 199 HOH HOH A . F 6 HOH 200 2204 200 HOH HOH A . F 6 HOH 201 2205 201 HOH HOH A . F 6 HOH 202 2206 202 HOH HOH A . F 6 HOH 203 2207 203 HOH HOH A . F 6 HOH 204 2208 204 HOH HOH A . F 6 HOH 205 2209 205 HOH HOH A . F 6 HOH 206 2210 206 HOH HOH A . F 6 HOH 207 2211 207 HOH HOH A . F 6 HOH 208 2212 208 HOH HOH A . F 6 HOH 209 2213 209 HOH HOH A . F 6 HOH 210 2214 210 HOH HOH A . F 6 HOH 211 2215 211 HOH HOH A . F 6 HOH 212 2216 212 HOH HOH A . F 6 HOH 213 2217 213 HOH HOH A . F 6 HOH 214 2218 214 HOH HOH A . F 6 HOH 215 2219 215 HOH HOH A . F 6 HOH 216 2220 216 HOH HOH A . F 6 HOH 217 2221 217 HOH HOH A . F 6 HOH 218 2222 218 HOH HOH A . F 6 HOH 219 2223 219 HOH HOH A . F 6 HOH 220 2224 220 HOH HOH A . F 6 HOH 221 2225 221 HOH HOH A . F 6 HOH 222 2226 222 HOH HOH A . F 6 HOH 223 2227 223 HOH HOH A . F 6 HOH 224 2228 224 HOH HOH A . F 6 HOH 225 2229 225 HOH HOH A . F 6 HOH 226 2230 226 HOH HOH A . F 6 HOH 227 2231 227 HOH HOH A . F 6 HOH 228 2232 228 HOH HOH A . F 6 HOH 229 2233 229 HOH HOH A . F 6 HOH 230 2234 230 HOH HOH A . F 6 HOH 231 2235 231 HOH HOH A . F 6 HOH 232 2236 232 HOH HOH A . F 6 HOH 233 2237 233 HOH HOH A . F 6 HOH 234 2238 234 HOH HOH A . F 6 HOH 235 2239 235 HOH HOH A . F 6 HOH 236 2240 236 HOH HOH A . F 6 HOH 237 2241 237 HOH HOH A . F 6 HOH 238 2242 238 HOH HOH A . F 6 HOH 239 2243 239 HOH HOH A . F 6 HOH 240 2244 240 HOH HOH A . F 6 HOH 241 2245 241 HOH HOH A . F 6 HOH 242 2246 242 HOH HOH A . F 6 HOH 243 2247 243 HOH HOH A . F 6 HOH 244 2248 244 HOH HOH A . F 6 HOH 245 2249 245 HOH HOH A . F 6 HOH 246 2250 246 HOH HOH A . F 6 HOH 247 2251 247 HOH HOH A . F 6 HOH 248 2252 248 HOH HOH A . F 6 HOH 249 2253 249 HOH HOH A . F 6 HOH 250 2254 250 HOH HOH A . F 6 HOH 251 2255 251 HOH HOH A . F 6 HOH 252 2256 252 HOH HOH A . F 6 HOH 253 2257 253 HOH HOH A . F 6 HOH 254 2258 254 HOH HOH A . F 6 HOH 255 2259 255 HOH HOH A . F 6 HOH 256 2260 256 HOH HOH A . F 6 HOH 257 2261 257 HOH HOH A . F 6 HOH 258 2262 258 HOH HOH A . F 6 HOH 259 2263 259 HOH HOH A . F 6 HOH 260 2264 260 HOH HOH A . F 6 HOH 261 2265 261 HOH HOH A . F 6 HOH 262 2266 262 HOH HOH A . F 6 HOH 263 2267 263 HOH HOH A . F 6 HOH 264 2268 264 HOH HOH A . F 6 HOH 265 2269 265 HOH HOH A . F 6 HOH 266 2270 266 HOH HOH A . F 6 HOH 267 2271 267 HOH HOH A . F 6 HOH 268 2272 268 HOH HOH A . F 6 HOH 269 2273 269 HOH HOH A . F 6 HOH 270 2274 270 HOH HOH A . F 6 HOH 271 2275 271 HOH HOH A . F 6 HOH 272 2276 272 HOH HOH A . F 6 HOH 273 2277 273 HOH HOH A . F 6 HOH 274 2278 274 HOH HOH A . F 6 HOH 275 2279 275 HOH HOH A . F 6 HOH 276 2280 276 HOH HOH A . F 6 HOH 277 2281 277 HOH HOH A . F 6 HOH 278 2282 278 HOH HOH A . F 6 HOH 279 2283 279 HOH HOH A . F 6 HOH 280 2284 280 HOH HOH A . F 6 HOH 281 2285 281 HOH HOH A . F 6 HOH 282 2286 282 HOH HOH A . F 6 HOH 283 2287 283 HOH HOH A . F 6 HOH 284 2288 284 HOH HOH A . F 6 HOH 285 2289 285 HOH HOH A . F 6 HOH 286 2290 286 HOH HOH A . F 6 HOH 287 2291 287 HOH HOH A . F 6 HOH 288 2292 288 HOH HOH A . F 6 HOH 289 2293 289 HOH HOH A . F 6 HOH 290 2294 290 HOH HOH A . F 6 HOH 291 2295 291 HOH HOH A . F 6 HOH 292 2296 292 HOH HOH A . F 6 HOH 293 2297 293 HOH HOH A . F 6 HOH 294 2298 294 HOH HOH A . F 6 HOH 295 2299 295 HOH HOH A . F 6 HOH 296 2300 296 HOH HOH A . F 6 HOH 297 2301 297 HOH HOH A . F 6 HOH 298 2302 298 HOH HOH A . F 6 HOH 299 2303 299 HOH HOH A . F 6 HOH 300 2304 300 HOH HOH A . F 6 HOH 301 2305 301 HOH HOH A . F 6 HOH 302 2306 302 HOH HOH A . F 6 HOH 303 2307 303 HOH HOH A . F 6 HOH 304 2308 304 HOH HOH A . F 6 HOH 305 2309 305 HOH HOH A . F 6 HOH 306 2310 306 HOH HOH A . F 6 HOH 307 2311 307 HOH HOH A . F 6 HOH 308 2312 308 HOH HOH A . F 6 HOH 309 2313 309 HOH HOH A . F 6 HOH 310 2314 310 HOH HOH A . F 6 HOH 311 2315 311 HOH HOH A . F 6 HOH 312 2316 312 HOH HOH A . F 6 HOH 313 2317 313 HOH HOH A . F 6 HOH 314 2318 314 HOH HOH A . F 6 HOH 315 2319 315 HOH HOH A . F 6 HOH 316 2320 316 HOH HOH A . F 6 HOH 317 2321 317 HOH HOH A . F 6 HOH 318 2322 318 HOH HOH A . F 6 HOH 319 2323 319 HOH HOH A . F 6 HOH 320 2324 320 HOH HOH A . F 6 HOH 321 2325 321 HOH HOH A . F 6 HOH 322 2326 322 HOH HOH A . F 6 HOH 323 2327 323 HOH HOH A . F 6 HOH 324 2328 324 HOH HOH A . F 6 HOH 325 2329 325 HOH HOH A . F 6 HOH 326 2330 326 HOH HOH A . F 6 HOH 327 2331 327 HOH HOH A . F 6 HOH 328 2332 328 HOH HOH A . F 6 HOH 329 2333 329 HOH HOH A . F 6 HOH 330 2334 330 HOH HOH A . F 6 HOH 331 2335 331 HOH HOH A . F 6 HOH 332 2336 332 HOH HOH A . F 6 HOH 333 2337 333 HOH HOH A . F 6 HOH 334 2338 334 HOH HOH A . F 6 HOH 335 2339 335 HOH HOH A . F 6 HOH 336 2340 336 HOH HOH A . F 6 HOH 337 2341 337 HOH HOH A . F 6 HOH 338 2342 338 HOH HOH A . F 6 HOH 339 2343 339 HOH HOH A . F 6 HOH 340 2344 340 HOH HOH A . F 6 HOH 341 2345 341 HOH HOH A . F 6 HOH 342 2346 342 HOH HOH A . F 6 HOH 343 2347 343 HOH HOH A . F 6 HOH 344 2348 344 HOH HOH A . F 6 HOH 345 2349 345 HOH HOH A . F 6 HOH 346 2350 346 HOH HOH A . F 6 HOH 347 2351 347 HOH HOH A . F 6 HOH 348 2352 348 HOH HOH A . F 6 HOH 349 2353 349 HOH HOH A . F 6 HOH 350 2354 350 HOH HOH A . F 6 HOH 351 2355 351 HOH HOH A . F 6 HOH 352 2356 352 HOH HOH A . F 6 HOH 353 2357 353 HOH HOH A . F 6 HOH 354 2358 354 HOH HOH A . F 6 HOH 355 2359 355 HOH HOH A . F 6 HOH 356 2360 356 HOH HOH A . F 6 HOH 357 2361 357 HOH HOH A . F 6 HOH 358 2362 358 HOH HOH A . F 6 HOH 359 2363 359 HOH HOH A . F 6 HOH 360 2364 360 HOH HOH A . F 6 HOH 361 2365 361 HOH HOH A . F 6 HOH 362 2366 362 HOH HOH A . F 6 HOH 363 2367 363 HOH HOH A . F 6 HOH 364 2368 364 HOH HOH A . F 6 HOH 365 2369 365 HOH HOH A . F 6 HOH 366 2370 366 HOH HOH A . F 6 HOH 367 2371 367 HOH HOH A . F 6 HOH 368 2372 368 HOH HOH A . F 6 HOH 369 2373 369 HOH HOH A . F 6 HOH 370 2374 370 HOH HOH A . F 6 HOH 371 2375 371 HOH HOH A . F 6 HOH 372 2376 372 HOH HOH A . F 6 HOH 373 2377 373 HOH HOH A . F 6 HOH 374 2378 374 HOH HOH A . F 6 HOH 375 2379 375 HOH HOH A . F 6 HOH 376 2380 376 HOH HOH A . F 6 HOH 377 2381 377 HOH HOH A . F 6 HOH 378 2382 378 HOH HOH A . F 6 HOH 379 2383 379 HOH HOH A . F 6 HOH 380 2384 380 HOH HOH A . F 6 HOH 381 2385 381 HOH HOH A . F 6 HOH 382 2386 382 HOH HOH A . F 6 HOH 383 2387 383 HOH HOH A . F 6 HOH 384 2388 384 HOH HOH A . F 6 HOH 385 2389 385 HOH HOH A . F 6 HOH 386 2390 386 HOH HOH A . F 6 HOH 387 2391 387 HOH HOH A . F 6 HOH 388 2392 388 HOH HOH A . F 6 HOH 389 2393 389 HOH HOH A . F 6 HOH 390 2394 390 HOH HOH A . F 6 HOH 391 2395 391 HOH HOH A . F 6 HOH 392 2396 392 HOH HOH A . F 6 HOH 393 2397 393 HOH HOH A . F 6 HOH 394 2398 394 HOH HOH A . F 6 HOH 395 2399 395 HOH HOH A . F 6 HOH 396 2400 396 HOH HOH A . F 6 HOH 397 2401 397 HOH HOH A . F 6 HOH 398 2402 398 HOH HOH A . F 6 HOH 399 2403 399 HOH HOH A . F 6 HOH 400 2404 400 HOH HOH A . F 6 HOH 401 2405 401 HOH HOH A . F 6 HOH 402 2406 402 HOH HOH A . F 6 HOH 403 2407 403 HOH HOH A . F 6 HOH 404 2408 404 HOH HOH A . F 6 HOH 405 2409 405 HOH HOH A . F 6 HOH 406 2410 406 HOH HOH A . F 6 HOH 407 2411 407 HOH HOH A . F 6 HOH 408 2412 408 HOH HOH A . F 6 HOH 409 2413 409 HOH HOH A . F 6 HOH 410 2414 410 HOH HOH A . F 6 HOH 411 2415 411 HOH HOH A . F 6 HOH 412 2416 412 HOH HOH A . F 6 HOH 413 2417 413 HOH HOH A . F 6 HOH 414 2418 414 HOH HOH A . F 6 HOH 415 2419 415 HOH HOH A . F 6 HOH 416 2420 416 HOH HOH A . F 6 HOH 417 2421 417 HOH HOH A . F 6 HOH 418 2422 418 HOH HOH A . F 6 HOH 419 2423 419 HOH HOH A . F 6 HOH 420 2424 420 HOH HOH A . F 6 HOH 421 2425 421 HOH HOH A . F 6 HOH 422 2426 422 HOH HOH A . F 6 HOH 423 2427 423 HOH HOH A . F 6 HOH 424 2428 424 HOH HOH A . F 6 HOH 425 2429 425 HOH HOH A . F 6 HOH 426 2430 426 HOH HOH A . F 6 HOH 427 2431 427 HOH HOH A . F 6 HOH 428 2432 428 HOH HOH A . F 6 HOH 429 2433 429 HOH HOH A . F 6 HOH 430 2434 430 HOH HOH A . F 6 HOH 431 2435 431 HOH HOH A . F 6 HOH 432 2436 432 HOH HOH A . F 6 HOH 433 2437 433 HOH HOH A . F 6 HOH 434 2438 434 HOH HOH A . F 6 HOH 435 2439 435 HOH HOH A . F 6 HOH 436 2440 436 HOH HOH A . F 6 HOH 437 2441 437 HOH HOH A . F 6 HOH 438 2442 438 HOH HOH A . F 6 HOH 439 2443 439 HOH HOH A . F 6 HOH 440 2444 440 HOH HOH A . F 6 HOH 441 2445 441 HOH HOH A . F 6 HOH 442 2446 442 HOH HOH A . F 6 HOH 443 2447 443 HOH HOH A . F 6 HOH 444 2448 444 HOH HOH A . F 6 HOH 445 2449 445 HOH HOH A . F 6 HOH 446 2450 446 HOH HOH A . F 6 HOH 447 2451 447 HOH HOH A . F 6 HOH 448 2452 448 HOH HOH A . F 6 HOH 449 2453 449 HOH HOH A . F 6 HOH 450 2454 450 HOH HOH A . F 6 HOH 451 2455 451 HOH HOH A . F 6 HOH 452 2456 452 HOH HOH A . F 6 HOH 453 2457 453 HOH HOH A . F 6 HOH 454 2458 454 HOH HOH A . F 6 HOH 455 2459 455 HOH HOH A . F 6 HOH 456 2460 456 HOH HOH A . F 6 HOH 457 2461 457 HOH HOH A . F 6 HOH 458 2462 458 HOH HOH A . F 6 HOH 459 2463 459 HOH HOH A . F 6 HOH 460 2464 460 HOH HOH A . F 6 HOH 461 2465 461 HOH HOH A . F 6 HOH 462 2466 462 HOH HOH A . F 6 HOH 463 2467 463 HOH HOH A . F 6 HOH 464 2468 464 HOH HOH A . F 6 HOH 465 2469 465 HOH HOH A . F 6 HOH 466 2470 466 HOH HOH A . F 6 HOH 467 2471 467 HOH HOH A . F 6 HOH 468 2472 468 HOH HOH A . F 6 HOH 469 2473 469 HOH HOH A . F 6 HOH 470 2474 470 HOH HOH A . F 6 HOH 471 2475 471 HOH HOH A . F 6 HOH 472 2476 472 HOH HOH A . F 6 HOH 473 2477 473 HOH HOH A . F 6 HOH 474 2478 474 HOH HOH A . F 6 HOH 475 2479 475 HOH HOH A . F 6 HOH 476 2480 476 HOH HOH A . F 6 HOH 477 2481 477 HOH HOH A . F 6 HOH 478 2482 478 HOH HOH A . F 6 HOH 479 2483 479 HOH HOH A . F 6 HOH 480 2484 480 HOH HOH A . F 6 HOH 481 2485 481 HOH HOH A . F 6 HOH 482 2486 482 HOH HOH A . F 6 HOH 483 2487 483 HOH HOH A . F 6 HOH 484 2488 484 HOH HOH A . F 6 HOH 485 2489 485 HOH HOH A . F 6 HOH 486 2490 486 HOH HOH A . F 6 HOH 487 2491 487 HOH HOH A . F 6 HOH 488 2492 488 HOH HOH A . F 6 HOH 489 2493 489 HOH HOH A . F 6 HOH 490 2494 490 HOH HOH A . F 6 HOH 491 2495 491 HOH HOH A . F 6 HOH 492 2496 492 HOH HOH A . F 6 HOH 493 2497 493 HOH HOH A . F 6 HOH 494 2498 494 HOH HOH A . F 6 HOH 495 2499 495 HOH HOH A . F 6 HOH 496 2500 496 HOH HOH A . F 6 HOH 497 2501 497 HOH HOH A . F 6 HOH 498 2502 498 HOH HOH A . F 6 HOH 499 2503 499 HOH HOH A . F 6 HOH 500 2504 500 HOH HOH A . F 6 HOH 501 2505 501 HOH HOH A . F 6 HOH 502 2506 502 HOH HOH A . F 6 HOH 503 2507 503 HOH HOH A . F 6 HOH 504 2508 504 HOH HOH A . F 6 HOH 505 2509 505 HOH HOH A . F 6 HOH 506 2510 506 HOH HOH A . F 6 HOH 507 2511 507 HOH HOH A . F 6 HOH 508 2512 508 HOH HOH A . F 6 HOH 509 2513 509 HOH HOH A . F 6 HOH 510 2514 510 HOH HOH A . F 6 HOH 511 2515 511 HOH HOH A . F 6 HOH 512 2516 512 HOH HOH A . F 6 HOH 513 2517 513 HOH HOH A . F 6 HOH 514 2518 514 HOH HOH A . F 6 HOH 515 2519 515 HOH HOH A . F 6 HOH 516 2520 516 HOH HOH A . F 6 HOH 517 2521 517 HOH HOH A . F 6 HOH 518 2522 518 HOH HOH A . F 6 HOH 519 2523 519 HOH HOH A . F 6 HOH 520 2524 520 HOH HOH A . F 6 HOH 521 2525 521 HOH HOH A . F 6 HOH 522 2526 522 HOH HOH A . F 6 HOH 523 2527 523 HOH HOH A . F 6 HOH 524 2528 524 HOH HOH A . F 6 HOH 525 2529 525 HOH HOH A . F 6 HOH 526 2530 526 HOH HOH A . F 6 HOH 527 2531 527 HOH HOH A . F 6 HOH 528 2532 528 HOH HOH A . F 6 HOH 529 2533 529 HOH HOH A . F 6 HOH 530 2534 530 HOH HOH A . F 6 HOH 531 2535 531 HOH HOH A . F 6 HOH 532 2536 532 HOH HOH A . F 6 HOH 533 2537 533 HOH HOH A . F 6 HOH 534 2538 534 HOH HOH A . F 6 HOH 535 2539 535 HOH HOH A . F 6 HOH 536 2540 536 HOH HOH A . F 6 HOH 537 2541 537 HOH HOH A . F 6 HOH 538 2542 538 HOH HOH A . F 6 HOH 539 2543 539 HOH HOH A . F 6 HOH 540 2544 540 HOH HOH A . F 6 HOH 541 2545 541 HOH HOH A . F 6 HOH 542 2546 542 HOH HOH A . F 6 HOH 543 2547 543 HOH HOH A . F 6 HOH 544 2548 544 HOH HOH A . F 6 HOH 545 2549 545 HOH HOH A . F 6 HOH 546 2550 546 HOH HOH A . F 6 HOH 547 2551 547 HOH HOH A . F 6 HOH 548 2552 548 HOH HOH A . F 6 HOH 549 2553 549 HOH HOH A . F 6 HOH 550 2554 550 HOH HOH A . F 6 HOH 551 2555 551 HOH HOH A . F 6 HOH 552 2556 552 HOH HOH A . F 6 HOH 553 2557 553 HOH HOH A . F 6 HOH 554 2558 554 HOH HOH A . F 6 HOH 555 2559 555 HOH HOH A . F 6 HOH 556 2560 556 HOH HOH A . F 6 HOH 557 2561 557 HOH HOH A . F 6 HOH 558 2562 558 HOH HOH A . F 6 HOH 559 2563 559 HOH HOH A . F 6 HOH 560 2564 560 HOH HOH A . F 6 HOH 561 2565 561 HOH HOH A . F 6 HOH 562 2566 562 HOH HOH A . F 6 HOH 563 2567 563 HOH HOH A . F 6 HOH 564 2568 564 HOH HOH A . F 6 HOH 565 2569 565 HOH HOH A . F 6 HOH 566 2570 566 HOH HOH A . F 6 HOH 567 2571 567 HOH HOH A . F 6 HOH 568 2572 568 HOH HOH A . F 6 HOH 569 2573 569 HOH HOH A . F 6 HOH 570 2574 570 HOH HOH A . F 6 HOH 571 2575 571 HOH HOH A . F 6 HOH 572 2576 572 HOH HOH A . F 6 HOH 573 2577 573 HOH HOH A . F 6 HOH 574 2578 574 HOH HOH A . F 6 HOH 575 2579 575 HOH HOH A . F 6 HOH 576 2580 576 HOH HOH A . F 6 HOH 577 2581 577 HOH HOH A . F 6 HOH 578 2582 578 HOH HOH A . F 6 HOH 579 2583 579 HOH HOH A . F 6 HOH 580 2584 580 HOH HOH A . F 6 HOH 581 2585 581 HOH HOH A . F 6 HOH 582 2586 582 HOH HOH A . F 6 HOH 583 2587 583 HOH HOH A . F 6 HOH 584 2588 584 HOH HOH A . F 6 HOH 585 2589 585 HOH HOH A . F 6 HOH 586 2590 586 HOH HOH A . F 6 HOH 587 2591 587 HOH HOH A . F 6 HOH 588 2592 588 HOH HOH A . F 6 HOH 589 2593 589 HOH HOH A . F 6 HOH 590 2594 590 HOH HOH A . F 6 HOH 591 2595 591 HOH HOH A . F 6 HOH 592 2596 592 HOH HOH A . F 6 HOH 593 2597 593 HOH HOH A . F 6 HOH 594 2598 594 HOH HOH A . F 6 HOH 595 2599 595 HOH HOH A . F 6 HOH 596 2600 596 HOH HOH A . F 6 HOH 597 2601 597 HOH HOH A . F 6 HOH 598 2602 598 HOH HOH A . F 6 HOH 599 2603 599 HOH HOH A . F 6 HOH 600 2604 600 HOH HOH A . F 6 HOH 601 2605 601 HOH HOH A . F 6 HOH 602 2606 602 HOH HOH A . F 6 HOH 603 2607 603 HOH HOH A . F 6 HOH 604 2608 604 HOH HOH A . F 6 HOH 605 2609 605 HOH HOH A . F 6 HOH 606 2610 606 HOH HOH A . F 6 HOH 607 2611 607 HOH HOH A . F 6 HOH 608 2612 608 HOH HOH A . F 6 HOH 609 2613 609 HOH HOH A . F 6 HOH 610 2614 610 HOH HOH A . F 6 HOH 611 2615 611 HOH HOH A . F 6 HOH 612 2616 612 HOH HOH A . F 6 HOH 613 2617 613 HOH HOH A . F 6 HOH 614 2618 614 HOH HOH A . F 6 HOH 615 2619 615 HOH HOH A . F 6 HOH 616 2620 616 HOH HOH A . F 6 HOH 617 2621 617 HOH HOH A . F 6 HOH 618 2622 618 HOH HOH A . F 6 HOH 619 2623 619 HOH HOH A . F 6 HOH 620 2624 620 HOH HOH A . F 6 HOH 621 2625 621 HOH HOH A . F 6 HOH 622 2626 622 HOH HOH A . F 6 HOH 623 2627 623 HOH HOH A . F 6 HOH 624 2628 624 HOH HOH A . F 6 HOH 625 2629 625 HOH HOH A . F 6 HOH 626 2630 626 HOH HOH A . F 6 HOH 627 2631 627 HOH HOH A . F 6 HOH 628 2632 628 HOH HOH A . F 6 HOH 629 2633 629 HOH HOH A . F 6 HOH 630 2634 630 HOH HOH A . F 6 HOH 631 2635 631 HOH HOH A . F 6 HOH 632 2636 632 HOH HOH A . F 6 HOH 633 2637 633 HOH HOH A . F 6 HOH 634 2638 634 HOH HOH A . F 6 HOH 635 2639 635 HOH HOH A . F 6 HOH 636 2640 636 HOH HOH A . F 6 HOH 637 2641 637 HOH HOH A . F 6 HOH 638 2642 638 HOH HOH A . F 6 HOH 639 2643 639 HOH HOH A . F 6 HOH 640 2644 640 HOH HOH A . F 6 HOH 641 2645 641 HOH HOH A . F 6 HOH 642 2646 642 HOH HOH A . F 6 HOH 643 2647 643 HOH HOH A . F 6 HOH 644 2648 644 HOH HOH A . F 6 HOH 645 2649 645 HOH HOH A . F 6 HOH 646 2650 646 HOH HOH A . F 6 HOH 647 2651 647 HOH HOH A . F 6 HOH 648 2652 648 HOH HOH A . F 6 HOH 649 2653 649 HOH HOH A . F 6 HOH 650 2654 650 HOH HOH A . F 6 HOH 651 2655 651 HOH HOH A . F 6 HOH 652 2656 652 HOH HOH A . F 6 HOH 653 2657 653 HOH HOH A . F 6 HOH 654 2658 654 HOH HOH A . F 6 HOH 655 2659 655 HOH HOH A . F 6 HOH 656 2660 656 HOH HOH A . F 6 HOH 657 2661 657 HOH HOH A . F 6 HOH 658 2662 658 HOH HOH A . F 6 HOH 659 2663 659 HOH HOH A . F 6 HOH 660 2664 660 HOH HOH A . F 6 HOH 661 2665 661 HOH HOH A . F 6 HOH 662 2666 662 HOH HOH A . F 6 HOH 663 2667 663 HOH HOH A . F 6 HOH 664 2668 664 HOH HOH A . F 6 HOH 665 2669 665 HOH HOH A . F 6 HOH 666 2670 666 HOH HOH A . F 6 HOH 667 2671 667 HOH HOH A . F 6 HOH 668 2672 668 HOH HOH A . F 6 HOH 669 2673 669 HOH HOH A . F 6 HOH 670 2674 670 HOH HOH A . F 6 HOH 671 2675 671 HOH HOH A . F 6 HOH 672 2676 672 HOH HOH A . F 6 HOH 673 2677 673 HOH HOH A . F 6 HOH 674 2678 674 HOH HOH A . F 6 HOH 675 2679 675 HOH HOH A . F 6 HOH 676 2680 676 HOH HOH A . F 6 HOH 677 2681 677 HOH HOH A . F 6 HOH 678 2682 678 HOH HOH A . F 6 HOH 679 2683 679 HOH HOH A . F 6 HOH 680 2684 680 HOH HOH A . F 6 HOH 681 2685 681 HOH HOH A . F 6 HOH 682 2686 682 HOH HOH A . F 6 HOH 683 2687 683 HOH HOH A . F 6 HOH 684 2688 684 HOH HOH A . F 6 HOH 685 2689 685 HOH HOH A . F 6 HOH 686 2690 686 HOH HOH A . F 6 HOH 687 2691 687 HOH HOH A . F 6 HOH 688 2692 688 HOH HOH A . F 6 HOH 689 2693 689 HOH HOH A . F 6 HOH 690 2694 690 HOH HOH A . F 6 HOH 691 2695 691 HOH HOH A . F 6 HOH 692 2696 692 HOH HOH A . F 6 HOH 693 2697 693 HOH HOH A . F 6 HOH 694 2698 694 HOH HOH A . F 6 HOH 695 2699 695 HOH HOH A . F 6 HOH 696 2700 696 HOH HOH A . F 6 HOH 697 2701 697 HOH HOH A . F 6 HOH 698 2702 698 HOH HOH A . F 6 HOH 699 2703 699 HOH HOH A . F 6 HOH 700 2704 700 HOH HOH A . F 6 HOH 701 2705 701 HOH HOH A . F 6 HOH 702 2706 702 HOH HOH A . F 6 HOH 703 2707 703 HOH HOH A . F 6 HOH 704 2708 704 HOH HOH A . F 6 HOH 705 2709 705 HOH HOH A . F 6 HOH 706 2710 706 HOH HOH A . F 6 HOH 707 2711 707 HOH HOH A . F 6 HOH 708 2712 708 HOH HOH A . F 6 HOH 709 2713 709 HOH HOH A . F 6 HOH 710 2714 710 HOH HOH A . F 6 HOH 711 2715 711 HOH HOH A . F 6 HOH 712 2716 712 HOH HOH A . F 6 HOH 713 2717 713 HOH HOH A . F 6 HOH 714 2718 714 HOH HOH A . F 6 HOH 715 2719 715 HOH HOH A . F 6 HOH 716 2720 716 HOH HOH A . F 6 HOH 717 2721 717 HOH HOH A . F 6 HOH 718 2722 718 HOH HOH A . F 6 HOH 719 2723 719 HOH HOH A . F 6 HOH 720 2724 720 HOH HOH A . F 6 HOH 721 2725 721 HOH HOH A . F 6 HOH 722 2726 722 HOH HOH A . F 6 HOH 723 2727 723 HOH HOH A . F 6 HOH 724 2728 724 HOH HOH A . F 6 HOH 725 2729 725 HOH HOH A . F 6 HOH 726 2730 726 HOH HOH A . F 6 HOH 727 2731 727 HOH HOH A . F 6 HOH 728 2732 728 HOH HOH A . F 6 HOH 729 2733 729 HOH HOH A . F 6 HOH 730 2734 730 HOH HOH A . F 6 HOH 731 2735 731 HOH HOH A . F 6 HOH 732 2736 732 HOH HOH A . F 6 HOH 733 2737 733 HOH HOH A . F 6 HOH 734 2738 734 HOH HOH A . F 6 HOH 735 2739 735 HOH HOH A . F 6 HOH 736 2740 736 HOH HOH A . F 6 HOH 737 2741 737 HOH HOH A . F 6 HOH 738 2742 738 HOH HOH A . F 6 HOH 739 2743 739 HOH HOH A . F 6 HOH 740 2744 740 HOH HOH A . F 6 HOH 741 2745 741 HOH HOH A . F 6 HOH 742 2746 742 HOH HOH A . F 6 HOH 743 2747 743 HOH HOH A . F 6 HOH 744 2748 744 HOH HOH A . F 6 HOH 745 2749 745 HOH HOH A . F 6 HOH 746 2750 746 HOH HOH A . F 6 HOH 747 2751 747 HOH HOH A . F 6 HOH 748 2752 748 HOH HOH A . F 6 HOH 749 2753 749 HOH HOH A . F 6 HOH 750 2754 750 HOH HOH A . F 6 HOH 751 2755 751 HOH HOH A . F 6 HOH 752 2756 752 HOH HOH A . F 6 HOH 753 2757 753 HOH HOH A . F 6 HOH 754 2758 754 HOH HOH A . F 6 HOH 755 2759 755 HOH HOH A . F 6 HOH 756 2760 756 HOH HOH A . F 6 HOH 757 2761 757 HOH HOH A . F 6 HOH 758 2762 758 HOH HOH A . F 6 HOH 759 2763 759 HOH HOH A . F 6 HOH 760 2764 760 HOH HOH A . F 6 HOH 761 2765 761 HOH HOH A . F 6 HOH 762 2766 762 HOH HOH A . F 6 HOH 763 2767 763 HOH HOH A . F 6 HOH 764 2768 764 HOH HOH A . F 6 HOH 765 2769 765 HOH HOH A . F 6 HOH 766 2770 766 HOH HOH A . F 6 HOH 767 2771 767 HOH HOH A . F 6 HOH 768 2772 768 HOH HOH A . F 6 HOH 769 2773 769 HOH HOH A . F 6 HOH 770 2774 770 HOH HOH A . F 6 HOH 771 2775 771 HOH HOH A . F 6 HOH 772 2776 772 HOH HOH A . F 6 HOH 773 2777 773 HOH HOH A . F 6 HOH 774 2778 774 HOH HOH A . F 6 HOH 775 2779 775 HOH HOH A . F 6 HOH 776 2780 776 HOH HOH A . F 6 HOH 777 2781 777 HOH HOH A . F 6 HOH 778 2782 778 HOH HOH A . F 6 HOH 779 2783 779 HOH HOH A . F 6 HOH 780 2784 780 HOH HOH A . F 6 HOH 781 2785 781 HOH HOH A . F 6 HOH 782 2786 782 HOH HOH A . F 6 HOH 783 2787 783 HOH HOH A . F 6 HOH 784 2788 784 HOH HOH A . F 6 HOH 785 2789 785 HOH HOH A . F 6 HOH 786 2790 786 HOH HOH A . F 6 HOH 787 2791 787 HOH HOH A . F 6 HOH 788 2792 788 HOH HOH A . F 6 HOH 789 2793 789 HOH HOH A . F 6 HOH 790 2794 790 HOH HOH A . F 6 HOH 791 2795 791 HOH HOH A . F 6 HOH 792 2796 792 HOH HOH A . F 6 HOH 793 2797 793 HOH HOH A . F 6 HOH 794 2798 794 HOH HOH A . F 6 HOH 795 2799 795 HOH HOH A . F 6 HOH 796 2800 796 HOH HOH A . F 6 HOH 797 2801 797 HOH HOH A . F 6 HOH 798 2802 798 HOH HOH A . F 6 HOH 799 2803 799 HOH HOH A . F 6 HOH 800 2804 800 HOH HOH A . F 6 HOH 801 2805 801 HOH HOH A . F 6 HOH 802 2806 802 HOH HOH A . F 6 HOH 803 2807 803 HOH HOH A . F 6 HOH 804 2808 804 HOH HOH A . F 6 HOH 805 2809 805 HOH HOH A . F 6 HOH 806 2810 806 HOH HOH A . F 6 HOH 807 2811 807 HOH HOH A . F 6 HOH 808 2812 808 HOH HOH A . F 6 HOH 809 2813 809 HOH HOH A . F 6 HOH 810 2814 810 HOH HOH A . F 6 HOH 811 2815 811 HOH HOH A . F 6 HOH 812 2816 812 HOH HOH A . F 6 HOH 813 2817 813 HOH HOH A . F 6 HOH 814 2818 814 HOH HOH A . F 6 HOH 815 2819 815 HOH HOH A . F 6 HOH 816 2820 816 HOH HOH A . F 6 HOH 817 2821 817 HOH HOH A . F 6 HOH 818 2822 818 HOH HOH A . F 6 HOH 819 2823 819 HOH HOH A . F 6 HOH 820 2824 820 HOH HOH A . F 6 HOH 821 2825 821 HOH HOH A . F 6 HOH 822 2826 822 HOH HOH A . F 6 HOH 823 2827 823 HOH HOH A . F 6 HOH 824 2828 824 HOH HOH A . F 6 HOH 825 2829 825 HOH HOH A . F 6 HOH 826 2830 826 HOH HOH A . F 6 HOH 827 2831 827 HOH HOH A . F 6 HOH 828 2832 828 HOH HOH A . F 6 HOH 829 2833 829 HOH HOH A . F 6 HOH 830 2834 830 HOH HOH A . F 6 HOH 831 2835 831 HOH HOH A . F 6 HOH 832 2836 832 HOH HOH A . F 6 HOH 833 2837 833 HOH HOH A . F 6 HOH 834 2838 834 HOH HOH A . F 6 HOH 835 2839 835 HOH HOH A . F 6 HOH 836 2840 836 HOH HOH A . F 6 HOH 837 2841 837 HOH HOH A . F 6 HOH 838 2842 838 HOH HOH A . F 6 HOH 839 2843 839 HOH HOH A . F 6 HOH 840 2844 840 HOH HOH A . F 6 HOH 841 2845 841 HOH HOH A . F 6 HOH 842 2846 842 HOH HOH A . F 6 HOH 843 2847 843 HOH HOH A . F 6 HOH 844 2848 844 HOH HOH A . F 6 HOH 845 2849 845 HOH HOH A . F 6 HOH 846 2850 846 HOH HOH A . F 6 HOH 847 2851 847 HOH HOH A . F 6 HOH 848 2852 848 HOH HOH A . F 6 HOH 849 2853 849 HOH HOH A . F 6 HOH 850 2854 850 HOH HOH A . F 6 HOH 851 2855 851 HOH HOH A . F 6 HOH 852 2856 852 HOH HOH A . F 6 HOH 853 2857 853 HOH HOH A . F 6 HOH 854 2858 854 HOH HOH A . F 6 HOH 855 2859 855 HOH HOH A . F 6 HOH 856 2860 856 HOH HOH A . F 6 HOH 857 2861 857 HOH HOH A . F 6 HOH 858 2862 858 HOH HOH A . F 6 HOH 859 2863 859 HOH HOH A . F 6 HOH 860 2864 860 HOH HOH A . F 6 HOH 861 2865 861 HOH HOH A . F 6 HOH 862 2866 862 HOH HOH A . F 6 HOH 863 2867 863 HOH HOH A . F 6 HOH 864 2868 864 HOH HOH A . F 6 HOH 865 2869 865 HOH HOH A . F 6 HOH 866 2870 866 HOH HOH A . F 6 HOH 867 2871 867 HOH HOH A . F 6 HOH 868 2872 868 HOH HOH A . F 6 HOH 869 2873 869 HOH HOH A . F 6 HOH 870 2874 870 HOH HOH A . F 6 HOH 871 2875 871 HOH HOH A . F 6 HOH 872 2876 872 HOH HOH A . F 6 HOH 873 2877 873 HOH HOH A . F 6 HOH 874 2878 874 HOH HOH A . F 6 HOH 875 2879 875 HOH HOH A . F 6 HOH 876 2880 876 HOH HOH A . F 6 HOH 877 2881 877 HOH HOH A . F 6 HOH 878 2882 878 HOH HOH A . F 6 HOH 879 2883 879 HOH HOH A . F 6 HOH 880 2884 880 HOH HOH A . F 6 HOH 881 2885 881 HOH HOH A . F 6 HOH 882 2886 882 HOH HOH A . F 6 HOH 883 2887 883 HOH HOH A . F 6 HOH 884 2888 884 HOH HOH A . F 6 HOH 885 2889 885 HOH HOH A . F 6 HOH 886 2890 886 HOH HOH A . F 6 HOH 887 2891 887 HOH HOH A . F 6 HOH 888 2892 888 HOH HOH A . F 6 HOH 889 2893 889 HOH HOH A . F 6 HOH 890 2894 890 HOH HOH A . F 6 HOH 891 2895 891 HOH HOH A . F 6 HOH 892 2896 892 HOH HOH A . F 6 HOH 893 2897 893 HOH HOH A . F 6 HOH 894 2898 894 HOH HOH A . F 6 HOH 895 2899 895 HOH HOH A . F 6 HOH 896 2900 896 HOH HOH A . F 6 HOH 897 2901 897 HOH HOH A . F 6 HOH 898 2902 898 HOH HOH A . F 6 HOH 899 2903 899 HOH HOH A . F 6 HOH 900 2904 900 HOH HOH A . F 6 HOH 901 2905 901 HOH HOH A . F 6 HOH 902 2906 902 HOH HOH A . F 6 HOH 903 2907 903 HOH HOH A . F 6 HOH 904 2908 904 HOH HOH A . F 6 HOH 905 2909 905 HOH HOH A . F 6 HOH 906 2910 906 HOH HOH A . F 6 HOH 907 2911 907 HOH HOH A . F 6 HOH 908 2912 908 HOH HOH A . F 6 HOH 909 2913 909 HOH HOH A . F 6 HOH 910 2914 910 HOH HOH A . F 6 HOH 911 2915 911 HOH HOH A . F 6 HOH 912 2916 912 HOH HOH A . F 6 HOH 913 2917 913 HOH HOH A . F 6 HOH 914 2918 914 HOH HOH A . F 6 HOH 915 2919 915 HOH HOH A . F 6 HOH 916 2920 916 HOH HOH A . F 6 HOH 917 2921 917 HOH HOH A . F 6 HOH 918 2922 918 HOH HOH A . F 6 HOH 919 2923 919 HOH HOH A . F 6 HOH 920 2924 920 HOH HOH A . F 6 HOH 921 2925 921 HOH HOH A . F 6 HOH 922 2926 922 HOH HOH A . F 6 HOH 923 2927 923 HOH HOH A . F 6 HOH 924 2928 924 HOH HOH A . F 6 HOH 925 2929 925 HOH HOH A . F 6 HOH 926 2930 926 HOH HOH A . F 6 HOH 927 2931 927 HOH HOH A . F 6 HOH 928 2932 928 HOH HOH A . F 6 HOH 929 2933 929 HOH HOH A . F 6 HOH 930 2934 930 HOH HOH A . F 6 HOH 931 2935 931 HOH HOH A . F 6 HOH 932 2936 932 HOH HOH A . F 6 HOH 933 2937 933 HOH HOH A . F 6 HOH 934 2938 934 HOH HOH A . F 6 HOH 935 2939 935 HOH HOH A . F 6 HOH 936 2940 936 HOH HOH A . F 6 HOH 937 2941 937 HOH HOH A . F 6 HOH 938 2942 938 HOH HOH A . F 6 HOH 939 2943 939 HOH HOH A . F 6 HOH 940 2944 940 HOH HOH A . F 6 HOH 941 2945 941 HOH HOH A . F 6 HOH 942 2946 942 HOH HOH A . F 6 HOH 943 2947 943 HOH HOH A . F 6 HOH 944 2948 944 HOH HOH A . F 6 HOH 945 2949 945 HOH HOH A . F 6 HOH 946 2950 946 HOH HOH A . F 6 HOH 947 2951 947 HOH HOH A . F 6 HOH 948 2952 948 HOH HOH A . F 6 HOH 949 2953 949 HOH HOH A . F 6 HOH 950 2954 950 HOH HOH A . F 6 HOH 951 2955 951 HOH HOH A . F 6 HOH 952 2956 952 HOH HOH A . F 6 HOH 953 2957 953 HOH HOH A . F 6 HOH 954 2958 954 HOH HOH A . F 6 HOH 955 2959 955 HOH HOH A . F 6 HOH 956 2960 956 HOH HOH A . F 6 HOH 957 2961 957 HOH HOH A . F 6 HOH 958 2962 958 HOH HOH A . F 6 HOH 959 2963 959 HOH HOH A . F 6 HOH 960 2964 960 HOH HOH A . F 6 HOH 961 2965 961 HOH HOH A . F 6 HOH 962 2966 962 HOH HOH A . F 6 HOH 963 2967 963 HOH HOH A . F 6 HOH 964 2968 964 HOH HOH A . F 6 HOH 965 2969 965 HOH HOH A . F 6 HOH 966 2970 966 HOH HOH A . F 6 HOH 967 2971 967 HOH HOH A . F 6 HOH 968 2972 968 HOH HOH A . F 6 HOH 969 2973 969 HOH HOH A . F 6 HOH 970 2974 970 HOH HOH A . F 6 HOH 971 2975 971 HOH HOH A . F 6 HOH 972 2976 972 HOH HOH A . F 6 HOH 973 2977 973 HOH HOH A . F 6 HOH 974 2978 974 HOH HOH A . F 6 HOH 975 2979 975 HOH HOH A . F 6 HOH 976 2980 976 HOH HOH A . F 6 HOH 977 2981 977 HOH HOH A . F 6 HOH 978 2982 978 HOH HOH A . F 6 HOH 979 2983 979 HOH HOH A . F 6 HOH 980 2984 980 HOH HOH A . F 6 HOH 981 2985 981 HOH HOH A . F 6 HOH 982 2986 982 HOH HOH A . F 6 HOH 983 2987 983 HOH HOH A . F 6 HOH 984 2988 984 HOH HOH A . F 6 HOH 985 2989 985 HOH HOH A . F 6 HOH 986 2990 986 HOH HOH A . F 6 HOH 987 2991 987 HOH HOH A . F 6 HOH 988 2992 988 HOH HOH A . F 6 HOH 989 2993 989 HOH HOH A . F 6 HOH 990 2994 990 HOH HOH A . F 6 HOH 991 2995 991 HOH HOH A . F 6 HOH 992 2996 992 HOH HOH A . F 6 HOH 993 2997 993 HOH HOH A . F 6 HOH 994 2998 994 HOH HOH A . F 6 HOH 995 2999 995 HOH HOH A . F 6 HOH 996 3000 996 HOH HOH A . F 6 HOH 997 3001 997 HOH HOH A . F 6 HOH 998 3002 998 HOH HOH A . F 6 HOH 999 3003 999 HOH HOH A . F 6 HOH 1000 3004 1000 HOH HOH A . F 6 HOH 1001 3005 1001 HOH HOH A . F 6 HOH 1002 3006 1002 HOH HOH A . F 6 HOH 1003 3007 1003 HOH HOH A . F 6 HOH 1004 3008 1004 HOH HOH A . F 6 HOH 1005 3009 1005 HOH HOH A . F 6 HOH 1006 3010 1006 HOH HOH A . F 6 HOH 1007 3011 1007 HOH HOH A . F 6 HOH 1008 3012 1008 HOH HOH A . F 6 HOH 1009 3013 1009 HOH HOH A . F 6 HOH 1010 3014 1010 HOH HOH A . F 6 HOH 1011 3015 1011 HOH HOH A . F 6 HOH 1012 3016 1012 HOH HOH A . F 6 HOH 1013 3017 1013 HOH HOH A . F 6 HOH 1014 3018 1014 HOH HOH A . F 6 HOH 1015 3019 1015 HOH HOH A . F 6 HOH 1016 3020 1016 HOH HOH A . F 6 HOH 1017 3021 1017 HOH HOH A . F 6 HOH 1018 3022 1018 HOH HOH A . F 6 HOH 1019 3023 1019 HOH HOH A . F 6 HOH 1020 3024 1020 HOH HOH A . F 6 HOH 1021 3025 1021 HOH HOH A . F 6 HOH 1022 3026 1022 HOH HOH A . F 6 HOH 1023 3027 1023 HOH HOH A . F 6 HOH 1024 3028 1024 HOH HOH A . F 6 HOH 1025 3029 1025 HOH HOH A . F 6 HOH 1026 3030 1026 HOH HOH A . F 6 HOH 1027 3031 1027 HOH HOH A . F 6 HOH 1028 3032 1028 HOH HOH A . F 6 HOH 1029 3033 1029 HOH HOH A . F 6 HOH 1030 3034 1030 HOH HOH A . F 6 HOH 1031 3035 1031 HOH HOH A . F 6 HOH 1032 3036 1032 HOH HOH A . F 6 HOH 1033 3037 1033 HOH HOH A . F 6 HOH 1034 3038 1034 HOH HOH A . F 6 HOH 1035 3039 1035 HOH HOH A . F 6 HOH 1036 3040 1036 HOH HOH A . F 6 HOH 1037 3041 1037 HOH HOH A . F 6 HOH 1038 3042 1038 HOH HOH A . F 6 HOH 1039 3043 1039 HOH HOH A . F 6 HOH 1040 3044 1040 HOH HOH A . F 6 HOH 1041 3045 1041 HOH HOH A . F 6 HOH 1042 3046 1042 HOH HOH A . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 194 _pdbx_struct_mod_residue.auth_asym_id A _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 194 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 F2 B D FMF . ? A FMF 2003 ? 1_555 101.0 ? 2 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O3 A D FMF . ? A FMF 2003 ? 1_555 93.8 ? 3 F2 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O3 A D FMF . ? A FMF 2003 ? 1_555 67.9 ? 4 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O3 B D FMF . ? A FMF 2003 ? 1_555 88.0 ? 5 F2 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O3 B D FMF . ? A FMF 2003 ? 1_555 68.5 ? 6 O3 A D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O3 B D FMF . ? A FMF 2003 ? 1_555 5.8 ? 7 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 101.3 ? 8 F2 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 153.3 ? 9 O3 A D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 96.2 ? 10 O3 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 98.0 ? 11 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 102.3 ? 12 F2 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 81.4 ? 13 O3 A D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 147.6 ? 14 O3 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 149.6 ? 15 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 107.7 ? 16 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 F2 A D FMF . ? A FMF 2003 ? 1_555 101.1 ? 17 F2 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 F2 A D FMF . ? A FMF 2003 ? 1_555 0.9 ? 18 O3 A D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 F2 A D FMF . ? A FMF 2003 ? 1_555 67.0 ? 19 O3 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 F2 A D FMF . ? A FMF 2003 ? 1_555 67.6 ? 20 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 F2 A D FMF . ? A FMF 2003 ? 1_555 152.7 ? 21 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 F2 A D FMF . ? A FMF 2003 ? 1_555 82.3 ? 22 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 161.2 ? 23 F2 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 63.3 ? 24 O3 A D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 71.2 ? 25 O3 B D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 76.7 ? 26 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 91.8 ? 27 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 86.2 ? 28 F2 A D FMF . ? A FMF 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 63.0 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2003-10-07 2 'Structure model' 1 1 2008-04-29 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal CNS refinement 1.0 ? 1 DENZO 'data reduction' . ? 2 SCALEPACK 'data scaling' . ? 3 CNS phasing . ? 4 # _pdbx_database_remark.id 999 _pdbx_database_remark.text ;SEQUENCE The E -> K conflict for residue 970 is noted in Swiss-Prot entry Q24451. ; # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OH A TYR 506 ? B O A HOH 2896 ? ? 1.55 2 1 O A HOH 2895 ? ? O A HOH 3046 ? ? 1.56 3 1 CE1 A TYR 435 ? B O A HOH 2594 ? ? 1.80 4 1 O A HOH 2337 ? ? O A HOH 2590 ? ? 1.86 5 1 OH A TYR 75 ? B O A HOH 2381 ? ? 1.87 6 1 CE1 A TYR 75 ? B O A HOH 2992 ? ? 2.02 7 1 OE1 A GLU 47 ? ? NH1 A ARG 51 ? ? 2.03 8 1 OE2 A GLU 130 ? ? O A HOH 2891 ? ? 2.10 9 1 OH A TYR 75 ? B O A HOH 3042 ? ? 2.14 10 1 CD2 A HIS 709 ? A O A HOH 3045 ? ? 2.16 # _pdbx_validate_symm_contact.id 1 _pdbx_validate_symm_contact.PDB_model_num 1 _pdbx_validate_symm_contact.auth_atom_id_1 OG _pdbx_validate_symm_contact.auth_asym_id_1 A _pdbx_validate_symm_contact.auth_comp_id_1 SER _pdbx_validate_symm_contact.auth_seq_id_1 53 _pdbx_validate_symm_contact.PDB_ins_code_1 ? _pdbx_validate_symm_contact.label_alt_id_1 B _pdbx_validate_symm_contact.site_symmetry_1 1_555 _pdbx_validate_symm_contact.auth_atom_id_2 O _pdbx_validate_symm_contact.auth_asym_id_2 A _pdbx_validate_symm_contact.auth_comp_id_2 HOH _pdbx_validate_symm_contact.auth_seq_id_2 2448 _pdbx_validate_symm_contact.PDB_ins_code_2 ? _pdbx_validate_symm_contact.label_alt_id_2 ? _pdbx_validate_symm_contact.site_symmetry_2 1_455 _pdbx_validate_symm_contact.dist 2.19 # loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 C A ASP 316 ? B N A LEU 317 ? ? 1.646 1.336 0.310 0.023 Y 2 1 SD A MET 501 ? ? CE A MET 501 ? ? 1.394 1.774 -0.380 0.056 N 3 1 CE2 A TYR 506 ? B CD2 A TYR 506 ? B 1.479 1.389 0.090 0.015 N 4 1 C A HIS 599 ? B N A HIS 600 ? ? 1.554 1.336 0.218 0.023 Y # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CA A ASP 316 ? B C A ASP 316 ? B N A LEU 317 ? ? 100.99 117.20 -16.21 2.20 Y 2 1 O A ASP 316 ? B C A ASP 316 ? B N A LEU 317 ? ? 134.32 122.70 11.62 1.60 Y 3 1 NE A ARG 343 ? ? CZ A ARG 343 ? ? NH2 A ARG 343 ? ? 117.30 120.30 -3.00 0.50 N 4 1 NE A ARG 427 ? ? CZ A ARG 427 ? ? NH1 A ARG 427 ? ? 124.13 120.30 3.83 0.50 N 5 1 NE A ARG 427 ? ? CZ A ARG 427 ? ? NH2 A ARG 427 ? ? 117.15 120.30 -3.15 0.50 N 6 1 O A TYR 435 ? B C A TYR 435 ? B N A VAL 436 ? ? 112.75 122.70 -9.95 1.60 Y 7 1 NE A ARG 457 ? ? CZ A ARG 457 ? ? NH2 A ARG 457 ? ? 117.18 120.30 -3.12 0.50 N 8 1 CG A MET 501 ? ? SD A MET 501 ? ? CE A MET 501 ? ? 89.12 100.20 -11.08 1.60 N 9 1 NE A ARG 565 ? ? CZ A ARG 565 ? ? NH2 A ARG 565 ? ? 117.17 120.30 -3.13 0.50 N 10 1 CA A HIS 599 ? B C A HIS 599 ? B N A HIS 600 ? ? 102.24 117.20 -14.96 2.20 Y 11 1 NE A ARG 963 ? ? CZ A ARG 963 ? ? NH2 A ARG 963 ? ? 117.03 120.30 -3.27 0.50 N 12 1 CA A LEU 979 ? A CB A LEU 979 ? A CG A LEU 979 ? A 131.25 115.30 15.95 2.30 N 13 1 CA A LEU 979 ? B CB A LEU 979 ? B CG A LEU 979 ? B 131.24 115.30 15.94 2.30 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 HIS A 79 ? ? -155.10 83.56 2 1 TRP A 95 ? ? -168.71 -84.36 3 1 ASP A 106 ? ? -133.89 -59.59 4 1 THR A 162 ? ? 68.34 -65.65 5 1 GLN A 227 ? ? -134.40 -49.77 6 1 ARG A 289 ? ? -97.73 34.79 7 1 ASP A 340 ? ? -170.10 -168.67 8 1 SER A 411 ? A 41.30 -125.23 9 1 SER A 411 ? B 46.56 -122.91 10 1 ILE A 549 ? ? -144.11 -46.47 11 1 LEU A 550 ? ? -168.44 116.49 12 1 PRO A 562 ? ? -82.15 39.81 13 1 ASN A 732 ? ? -93.04 59.53 14 1 SER A 762 ? ? 71.76 -4.56 15 1 ILE A 831 ? ? -118.80 78.15 16 1 SER A 833 ? ? -150.19 -14.74 17 1 ASP A 839 ? ? -126.57 -161.22 18 1 GLU A 991 ? ? 13.54 109.47 19 1 GLU A 992 ? ? -121.33 -122.45 20 1 HIS A 993 ? ? -18.85 99.89 # loop_ _pdbx_validate_main_chain_plane.id _pdbx_validate_main_chain_plane.PDB_model_num _pdbx_validate_main_chain_plane.auth_comp_id _pdbx_validate_main_chain_plane.auth_asym_id _pdbx_validate_main_chain_plane.auth_seq_id _pdbx_validate_main_chain_plane.PDB_ins_code _pdbx_validate_main_chain_plane.label_alt_id _pdbx_validate_main_chain_plane.improper_torsion_angle 1 1 TYR A 435 ? B -10.58 2 1 HIS A 599 ? B 11.50 # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C4 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id A _pdbx_validate_chiral.auth_comp_id MPD _pdbx_validate_chiral.auth_seq_id 2002 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # _pdbx_validate_polymer_linkage.id 1 _pdbx_validate_polymer_linkage.PDB_model_num 1 _pdbx_validate_polymer_linkage.auth_atom_id_1 C _pdbx_validate_polymer_linkage.auth_asym_id_1 A _pdbx_validate_polymer_linkage.auth_comp_id_1 ASP _pdbx_validate_polymer_linkage.auth_seq_id_1 316 _pdbx_validate_polymer_linkage.PDB_ins_code_1 ? _pdbx_validate_polymer_linkage.label_alt_id_1 B _pdbx_validate_polymer_linkage.auth_atom_id_2 N _pdbx_validate_polymer_linkage.auth_asym_id_2 A _pdbx_validate_polymer_linkage.auth_comp_id_2 LEU _pdbx_validate_polymer_linkage.auth_seq_id_2 317 _pdbx_validate_polymer_linkage.PDB_ins_code_2 ? _pdbx_validate_polymer_linkage.label_alt_id_2 ? _pdbx_validate_polymer_linkage.dist 1.65 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ARG 1 ? A ARG 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A SER 3 ? A SER 3 4 1 Y 1 A HIS 4 ? A HIS 4 5 1 Y 1 A HIS 5 ? A HIS 5 6 1 Y 1 A HIS 6 ? A HIS 6 7 1 Y 1 A HIS 7 ? A HIS 7 8 1 Y 1 A HIS 8 ? A HIS 8 9 1 Y 1 A HIS 9 ? A HIS 9 10 1 Y 1 A GLY 10 ? A GLY 10 11 1 Y 1 A GLU 11 ? A GLU 11 12 1 Y 1 A PHE 12 ? A PHE 12 13 1 Y 1 A ASP 13 ? A ASP 13 14 1 Y 1 A ASP 14 ? A ASP 14 15 1 Y 1 A PRO 15 ? A PRO 15 16 1 Y 1 A ILE 16 ? A ILE 16 17 1 Y 1 A ARG 17 ? A ARG 17 18 1 Y 1 A PRO 18 ? A PRO 18 19 1 Y 1 A PRO 19 ? A PRO 19 20 1 Y 1 A LEU 20 ? A LEU 20 21 1 Y 1 A LYS 21 ? A LYS 21 22 1 Y 1 A VAL 22 ? A VAL 22 23 1 Y 1 A ALA 23 ? A ALA 23 24 1 Y 1 A ARG 24 ? A ARG 24 25 1 Y 1 A SER 25 ? A SER 25 26 1 Y 1 A PRO 26 ? A PRO 26 27 1 Y 1 A ARG 27 ? A ARG 27 28 1 Y 1 A PRO 28 ? A PRO 28 29 1 Y 1 A GLY 29 ? A GLY 29 30 1 Y 1 A GLN 30 ? A GLN 30 31 1 Y 1 A SER 1045 ? A SER 1045 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'ZINC ION' ZN 4 '2-DEOXY-2-FLUOROHEXOPYRANOSYL FLUORIDE' FMF 5 '(4S)-2-METHYL-2,4-PENTANEDIOL' MPD 6 water HOH #