data_1QWU # _entry.id 1QWU # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 1QWU RCSB RCSB020164 WWPDB D_1000020164 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1QWN . unspecified PDB 1HTY . unspecified PDB 1HWW . unspecified PDB 1HXK . unspecified PDB 1PS3 . unspecified PDB 1QW9 . unspecified PDB 1QX1 . unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 1QWU _pdbx_database_status.recvd_initial_deposition_date 2003-09-03 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.SG_entry . _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Numao, S.' 1 'Kuntz, D.A.' 2 'Withers, S.G.' 3 'Rose, D.R.' 4 # _citation.id primary _citation.title ;Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates. ; _citation.journal_abbrev J.Biol.Chem. _citation.journal_volume 278 _citation.page_first 48074 _citation.page_last 48083 _citation.year 2003 _citation.journal_id_ASTM JBCHA3 _citation.country US _citation.journal_id_ISSN 0021-9258 _citation.journal_id_CSD 0071 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 12960159 _citation.pdbx_database_id_DOI 10.1074/jbc.M309249200 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Numao, S.' 1 primary 'Kuntz, D.A.' 2 primary 'Withers, S.G.' 3 primary 'Rose, D.R.' 4 # _cell.entry_id 1QWU _cell.length_a 68.850 _cell.length_b 109.799 _cell.length_c 138.765 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? # _symmetry.entry_id 1QWU _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Alpha-mannosidase II' 119700.633 1 3.2.1.114 D341N 'Family 38 catalytic domain (residues 94-1108)' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 4 non-polymer syn '5-FLUORO-BETA-L-GULOSYL FLUORIDE' 200.137 1 ? ? ? ? 5 non-polymer syn '(4S)-2-METHYL-2,4-PENTANEDIOL' 118.174 1 ? ? ? ? 6 water nat water 18.015 1025 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDNFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_seq_one_letter_code_can ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDNFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 SER n 1 3 SER n 1 4 HIS n 1 5 HIS n 1 6 HIS n 1 7 HIS n 1 8 HIS n 1 9 HIS n 1 10 GLY n 1 11 GLU n 1 12 PHE n 1 13 ASP n 1 14 ASP n 1 15 PRO n 1 16 ILE n 1 17 ARG n 1 18 PRO n 1 19 PRO n 1 20 LEU n 1 21 LYS n 1 22 VAL n 1 23 ALA n 1 24 ARG n 1 25 SER n 1 26 PRO n 1 27 ARG n 1 28 PRO n 1 29 GLY n 1 30 GLN n 1 31 CYS n 1 32 GLN n 1 33 ASP n 1 34 VAL n 1 35 VAL n 1 36 GLN n 1 37 ASP n 1 38 VAL n 1 39 PRO n 1 40 ASN n 1 41 VAL n 1 42 ASP n 1 43 VAL n 1 44 GLN n 1 45 MET n 1 46 LEU n 1 47 GLU n 1 48 LEU n 1 49 TYR n 1 50 ASP n 1 51 ARG n 1 52 MET n 1 53 SER n 1 54 PHE n 1 55 LYS n 1 56 ASP n 1 57 ILE n 1 58 ASP n 1 59 GLY n 1 60 GLY n 1 61 VAL n 1 62 TRP n 1 63 LYS n 1 64 GLN n 1 65 GLY n 1 66 TRP n 1 67 ASN n 1 68 ILE n 1 69 LYS n 1 70 TYR n 1 71 ASP n 1 72 PRO n 1 73 LEU n 1 74 LYS n 1 75 TYR n 1 76 ASN n 1 77 ALA n 1 78 HIS n 1 79 HIS n 1 80 LYS n 1 81 LEU n 1 82 LYS n 1 83 VAL n 1 84 PHE n 1 85 VAL n 1 86 VAL n 1 87 PRO n 1 88 HIS n 1 89 SER n 1 90 HIS n 1 91 ASN n 1 92 ASP n 1 93 PRO n 1 94 GLY n 1 95 TRP n 1 96 ILE n 1 97 GLN n 1 98 THR n 1 99 PHE n 1 100 GLU n 1 101 GLU n 1 102 TYR n 1 103 TYR n 1 104 GLN n 1 105 HIS n 1 106 ASP n 1 107 THR n 1 108 LYS n 1 109 HIS n 1 110 ILE n 1 111 LEU n 1 112 SER n 1 113 ASN n 1 114 ALA n 1 115 LEU n 1 116 ARG n 1 117 HIS n 1 118 LEU n 1 119 HIS n 1 120 ASP n 1 121 ASN n 1 122 PRO n 1 123 GLU n 1 124 MET n 1 125 LYS n 1 126 PHE n 1 127 ILE n 1 128 TRP n 1 129 ALA n 1 130 GLU n 1 131 ILE n 1 132 SER n 1 133 TYR n 1 134 PHE n 1 135 ALA n 1 136 ARG n 1 137 PHE n 1 138 TYR n 1 139 HIS n 1 140 ASP n 1 141 LEU n 1 142 GLY n 1 143 GLU n 1 144 ASN n 1 145 LYS n 1 146 LYS n 1 147 LEU n 1 148 GLN n 1 149 MET n 1 150 LYS n 1 151 SER n 1 152 ILE n 1 153 VAL n 1 154 LYS n 1 155 ASN n 1 156 GLY n 1 157 GLN n 1 158 LEU n 1 159 GLU n 1 160 PHE n 1 161 VAL n 1 162 THR n 1 163 GLY n 1 164 GLY n 1 165 TRP n 1 166 VAL n 1 167 MET n 1 168 PRO n 1 169 ASP n 1 170 GLU n 1 171 ALA n 1 172 ASN n 1 173 SER n 1 174 HIS n 1 175 TRP n 1 176 ARG n 1 177 ASN n 1 178 VAL n 1 179 LEU n 1 180 LEU n 1 181 GLN n 1 182 LEU n 1 183 THR n 1 184 GLU n 1 185 GLY n 1 186 GLN n 1 187 THR n 1 188 TRP n 1 189 LEU n 1 190 LYS n 1 191 GLN n 1 192 PHE n 1 193 MET n 1 194 ASN n 1 195 VAL n 1 196 THR n 1 197 PRO n 1 198 THR n 1 199 ALA n 1 200 SER n 1 201 TRP n 1 202 ALA n 1 203 ILE n 1 204 ASP n 1 205 PRO n 1 206 PHE n 1 207 GLY n 1 208 HIS n 1 209 SER n 1 210 PRO n 1 211 THR n 1 212 MET n 1 213 PRO n 1 214 TYR n 1 215 ILE n 1 216 LEU n 1 217 GLN n 1 218 LYS n 1 219 SER n 1 220 GLY n 1 221 PHE n 1 222 LYS n 1 223 ASN n 1 224 MET n 1 225 LEU n 1 226 ILE n 1 227 GLN n 1 228 ARG n 1 229 THR n 1 230 HIS n 1 231 TYR n 1 232 SER n 1 233 VAL n 1 234 LYS n 1 235 LYS n 1 236 GLU n 1 237 LEU n 1 238 ALA n 1 239 GLN n 1 240 GLN n 1 241 ARG n 1 242 GLN n 1 243 LEU n 1 244 GLU n 1 245 PHE n 1 246 LEU n 1 247 TRP n 1 248 ARG n 1 249 GLN n 1 250 ILE n 1 251 TRP n 1 252 ASP n 1 253 ASN n 1 254 LYS n 1 255 GLY n 1 256 ASP n 1 257 THR n 1 258 ALA n 1 259 LEU n 1 260 PHE n 1 261 THR n 1 262 HIS n 1 263 MET n 1 264 MET n 1 265 PRO n 1 266 PHE n 1 267 TYR n 1 268 SER n 1 269 TYR n 1 270 ASP n 1 271 ILE n 1 272 PRO n 1 273 HIS n 1 274 THR n 1 275 CYS n 1 276 GLY n 1 277 PRO n 1 278 ASP n 1 279 PRO n 1 280 LYS n 1 281 VAL n 1 282 CYS n 1 283 CYS n 1 284 GLN n 1 285 PHE n 1 286 ASP n 1 287 PHE n 1 288 LYS n 1 289 ARG n 1 290 MET n 1 291 GLY n 1 292 SER n 1 293 PHE n 1 294 GLY n 1 295 LEU n 1 296 SER n 1 297 CYS n 1 298 PRO n 1 299 TRP n 1 300 LYS n 1 301 VAL n 1 302 PRO n 1 303 PRO n 1 304 ARG n 1 305 THR n 1 306 ILE n 1 307 SER n 1 308 ASP n 1 309 GLN n 1 310 ASN n 1 311 VAL n 1 312 ALA n 1 313 ALA n 1 314 ARG n 1 315 SER n 1 316 ASP n 1 317 LEU n 1 318 LEU n 1 319 VAL n 1 320 ASP n 1 321 GLN n 1 322 TRP n 1 323 LYS n 1 324 LYS n 1 325 LYS n 1 326 ALA n 1 327 GLU n 1 328 LEU n 1 329 TYR n 1 330 ARG n 1 331 THR n 1 332 ASN n 1 333 VAL n 1 334 LEU n 1 335 LEU n 1 336 ILE n 1 337 PRO n 1 338 LEU n 1 339 GLY n 1 340 ASP n 1 341 ASN n 1 342 PHE n 1 343 ARG n 1 344 PHE n 1 345 LYS n 1 346 GLN n 1 347 ASN n 1 348 THR n 1 349 GLU n 1 350 TRP n 1 351 ASP n 1 352 VAL n 1 353 GLN n 1 354 ARG n 1 355 VAL n 1 356 ASN n 1 357 TYR n 1 358 GLU n 1 359 ARG n 1 360 LEU n 1 361 PHE n 1 362 GLU n 1 363 HIS n 1 364 ILE n 1 365 ASN n 1 366 SER n 1 367 GLN n 1 368 ALA n 1 369 HIS n 1 370 PHE n 1 371 ASN n 1 372 VAL n 1 373 GLN n 1 374 ALA n 1 375 GLN n 1 376 PHE n 1 377 GLY n 1 378 THR n 1 379 LEU n 1 380 GLN n 1 381 GLU n 1 382 TYR n 1 383 PHE n 1 384 ASP n 1 385 ALA n 1 386 VAL n 1 387 HIS n 1 388 GLN n 1 389 ALA n 1 390 GLU n 1 391 ARG n 1 392 ALA n 1 393 GLY n 1 394 GLN n 1 395 ALA n 1 396 GLU n 1 397 PHE n 1 398 PRO n 1 399 THR n 1 400 LEU n 1 401 SER n 1 402 GLY n 1 403 ASP n 1 404 PHE n 1 405 PHE n 1 406 THR n 1 407 TYR n 1 408 ALA n 1 409 ASP n 1 410 ARG n 1 411 SER n 1 412 ASP n 1 413 ASN n 1 414 TYR n 1 415 TRP n 1 416 SER n 1 417 GLY n 1 418 TYR n 1 419 TYR n 1 420 THR n 1 421 SER n 1 422 ARG n 1 423 PRO n 1 424 TYR n 1 425 HIS n 1 426 LYS n 1 427 ARG n 1 428 MET n 1 429 ASP n 1 430 ARG n 1 431 VAL n 1 432 LEU n 1 433 MET n 1 434 HIS n 1 435 TYR n 1 436 VAL n 1 437 ARG n 1 438 ALA n 1 439 ALA n 1 440 GLU n 1 441 MET n 1 442 LEU n 1 443 SER n 1 444 ALA n 1 445 TRP n 1 446 HIS n 1 447 SER n 1 448 TRP n 1 449 ASP n 1 450 GLY n 1 451 MET n 1 452 ALA n 1 453 ARG n 1 454 ILE n 1 455 GLU n 1 456 GLU n 1 457 ARG n 1 458 LEU n 1 459 GLU n 1 460 GLN n 1 461 ALA n 1 462 ARG n 1 463 ARG n 1 464 GLU n 1 465 LEU n 1 466 SER n 1 467 LEU n 1 468 PHE n 1 469 GLN n 1 470 HIS n 1 471 HIS n 1 472 ASP n 1 473 GLY n 1 474 ILE n 1 475 THR n 1 476 GLY n 1 477 THR n 1 478 ALA n 1 479 LYS n 1 480 THR n 1 481 HIS n 1 482 VAL n 1 483 VAL n 1 484 VAL n 1 485 ASP n 1 486 TYR n 1 487 GLU n 1 488 GLN n 1 489 ARG n 1 490 MET n 1 491 GLN n 1 492 GLU n 1 493 ALA n 1 494 LEU n 1 495 LYS n 1 496 ALA n 1 497 CYS n 1 498 GLN n 1 499 MET n 1 500 VAL n 1 501 MET n 1 502 GLN n 1 503 GLN n 1 504 SER n 1 505 VAL n 1 506 TYR n 1 507 ARG n 1 508 LEU n 1 509 LEU n 1 510 THR n 1 511 LYS n 1 512 PRO n 1 513 SER n 1 514 ILE n 1 515 TYR n 1 516 SER n 1 517 PRO n 1 518 ASP n 1 519 PHE n 1 520 SER n 1 521 PHE n 1 522 SER n 1 523 TYR n 1 524 PHE n 1 525 THR n 1 526 LEU n 1 527 ASP n 1 528 ASP n 1 529 SER n 1 530 ARG n 1 531 TRP n 1 532 PRO n 1 533 GLY n 1 534 SER n 1 535 GLY n 1 536 VAL n 1 537 GLU n 1 538 ASP n 1 539 SER n 1 540 ARG n 1 541 THR n 1 542 THR n 1 543 ILE n 1 544 ILE n 1 545 LEU n 1 546 GLY n 1 547 GLU n 1 548 ASP n 1 549 ILE n 1 550 LEU n 1 551 PRO n 1 552 SER n 1 553 LYS n 1 554 HIS n 1 555 VAL n 1 556 VAL n 1 557 MET n 1 558 HIS n 1 559 ASN n 1 560 THR n 1 561 LEU n 1 562 PRO n 1 563 HIS n 1 564 TRP n 1 565 ARG n 1 566 GLU n 1 567 GLN n 1 568 LEU n 1 569 VAL n 1 570 ASP n 1 571 PHE n 1 572 TYR n 1 573 VAL n 1 574 SER n 1 575 SER n 1 576 PRO n 1 577 PHE n 1 578 VAL n 1 579 SER n 1 580 VAL n 1 581 THR n 1 582 ASP n 1 583 LEU n 1 584 ALA n 1 585 ASN n 1 586 ASN n 1 587 PRO n 1 588 VAL n 1 589 GLU n 1 590 ALA n 1 591 GLN n 1 592 VAL n 1 593 SER n 1 594 PRO n 1 595 VAL n 1 596 TRP n 1 597 SER n 1 598 TRP n 1 599 HIS n 1 600 HIS n 1 601 ASP n 1 602 THR n 1 603 LEU n 1 604 THR n 1 605 LYS n 1 606 THR n 1 607 ILE n 1 608 HIS n 1 609 PRO n 1 610 GLN n 1 611 GLY n 1 612 SER n 1 613 THR n 1 614 THR n 1 615 LYS n 1 616 TYR n 1 617 ARG n 1 618 ILE n 1 619 ILE n 1 620 PHE n 1 621 LYS n 1 622 ALA n 1 623 ARG n 1 624 VAL n 1 625 PRO n 1 626 PRO n 1 627 MET n 1 628 GLY n 1 629 LEU n 1 630 ALA n 1 631 THR n 1 632 TYR n 1 633 VAL n 1 634 LEU n 1 635 THR n 1 636 ILE n 1 637 SER n 1 638 ASP n 1 639 SER n 1 640 LYS n 1 641 PRO n 1 642 GLU n 1 643 HIS n 1 644 THR n 1 645 SER n 1 646 TYR n 1 647 ALA n 1 648 SER n 1 649 ASN n 1 650 LEU n 1 651 LEU n 1 652 LEU n 1 653 ARG n 1 654 LYS n 1 655 ASN n 1 656 PRO n 1 657 THR n 1 658 SER n 1 659 LEU n 1 660 PRO n 1 661 LEU n 1 662 GLY n 1 663 GLN n 1 664 TYR n 1 665 PRO n 1 666 GLU n 1 667 ASP n 1 668 VAL n 1 669 LYS n 1 670 PHE n 1 671 GLY n 1 672 ASP n 1 673 PRO n 1 674 ARG n 1 675 GLU n 1 676 ILE n 1 677 SER n 1 678 LEU n 1 679 ARG n 1 680 VAL n 1 681 GLY n 1 682 ASN n 1 683 GLY n 1 684 PRO n 1 685 THR n 1 686 LEU n 1 687 ALA n 1 688 PHE n 1 689 SER n 1 690 GLU n 1 691 GLN n 1 692 GLY n 1 693 LEU n 1 694 LEU n 1 695 LYS n 1 696 SER n 1 697 ILE n 1 698 GLN n 1 699 LEU n 1 700 THR n 1 701 GLN n 1 702 ASP n 1 703 SER n 1 704 PRO n 1 705 HIS n 1 706 VAL n 1 707 PRO n 1 708 VAL n 1 709 HIS n 1 710 PHE n 1 711 LYS n 1 712 PHE n 1 713 LEU n 1 714 LYS n 1 715 TYR n 1 716 GLY n 1 717 VAL n 1 718 ARG n 1 719 SER n 1 720 HIS n 1 721 GLY n 1 722 ASP n 1 723 ARG n 1 724 SER n 1 725 GLY n 1 726 ALA n 1 727 TYR n 1 728 LEU n 1 729 PHE n 1 730 LEU n 1 731 PRO n 1 732 ASN n 1 733 GLY n 1 734 PRO n 1 735 ALA n 1 736 SER n 1 737 PRO n 1 738 VAL n 1 739 GLU n 1 740 LEU n 1 741 GLY n 1 742 GLN n 1 743 PRO n 1 744 VAL n 1 745 VAL n 1 746 LEU n 1 747 VAL n 1 748 THR n 1 749 LYS n 1 750 GLY n 1 751 LYS n 1 752 LEU n 1 753 GLU n 1 754 SER n 1 755 SER n 1 756 VAL n 1 757 SER n 1 758 VAL n 1 759 GLY n 1 760 LEU n 1 761 PRO n 1 762 SER n 1 763 VAL n 1 764 VAL n 1 765 HIS n 1 766 GLN n 1 767 THR n 1 768 ILE n 1 769 MET n 1 770 ARG n 1 771 GLY n 1 772 GLY n 1 773 ALA n 1 774 PRO n 1 775 GLU n 1 776 ILE n 1 777 ARG n 1 778 ASN n 1 779 LEU n 1 780 VAL n 1 781 ASP n 1 782 ILE n 1 783 GLY n 1 784 SER n 1 785 LEU n 1 786 ASP n 1 787 ASN n 1 788 THR n 1 789 GLU n 1 790 ILE n 1 791 VAL n 1 792 MET n 1 793 ARG n 1 794 LEU n 1 795 GLU n 1 796 THR n 1 797 HIS n 1 798 ILE n 1 799 ASP n 1 800 SER n 1 801 GLY n 1 802 ASP n 1 803 ILE n 1 804 PHE n 1 805 TYR n 1 806 THR n 1 807 ASP n 1 808 LEU n 1 809 ASN n 1 810 GLY n 1 811 LEU n 1 812 GLN n 1 813 PHE n 1 814 ILE n 1 815 LYS n 1 816 ARG n 1 817 ARG n 1 818 ARG n 1 819 LEU n 1 820 ASP n 1 821 LYS n 1 822 LEU n 1 823 PRO n 1 824 LEU n 1 825 GLN n 1 826 ALA n 1 827 ASN n 1 828 TYR n 1 829 TYR n 1 830 PRO n 1 831 ILE n 1 832 PRO n 1 833 SER n 1 834 GLY n 1 835 MET n 1 836 PHE n 1 837 ILE n 1 838 GLU n 1 839 ASP n 1 840 ALA n 1 841 ASN n 1 842 THR n 1 843 ARG n 1 844 LEU n 1 845 THR n 1 846 LEU n 1 847 LEU n 1 848 THR n 1 849 GLY n 1 850 GLN n 1 851 PRO n 1 852 LEU n 1 853 GLY n 1 854 GLY n 1 855 SER n 1 856 SER n 1 857 LEU n 1 858 ALA n 1 859 SER n 1 860 GLY n 1 861 GLU n 1 862 LEU n 1 863 GLU n 1 864 ILE n 1 865 MET n 1 866 GLN n 1 867 ASP n 1 868 ARG n 1 869 ARG n 1 870 LEU n 1 871 ALA n 1 872 SER n 1 873 ASP n 1 874 ASP n 1 875 GLU n 1 876 ARG n 1 877 GLY n 1 878 LEU n 1 879 GLY n 1 880 GLN n 1 881 GLY n 1 882 VAL n 1 883 LEU n 1 884 ASP n 1 885 ASN n 1 886 LYS n 1 887 PRO n 1 888 VAL n 1 889 LEU n 1 890 HIS n 1 891 ILE n 1 892 TYR n 1 893 ARG n 1 894 LEU n 1 895 VAL n 1 896 LEU n 1 897 GLU n 1 898 LYS n 1 899 VAL n 1 900 ASN n 1 901 ASN n 1 902 CYS n 1 903 VAL n 1 904 ARG n 1 905 PRO n 1 906 SER n 1 907 LYS n 1 908 LEU n 1 909 HIS n 1 910 PRO n 1 911 ALA n 1 912 GLY n 1 913 TYR n 1 914 LEU n 1 915 THR n 1 916 SER n 1 917 ALA n 1 918 ALA n 1 919 HIS n 1 920 LYS n 1 921 ALA n 1 922 SER n 1 923 GLN n 1 924 SER n 1 925 LEU n 1 926 LEU n 1 927 ASP n 1 928 PRO n 1 929 LEU n 1 930 ASP n 1 931 LYS n 1 932 PHE n 1 933 ILE n 1 934 PHE n 1 935 ALA n 1 936 GLU n 1 937 ASN n 1 938 GLU n 1 939 TRP n 1 940 ILE n 1 941 GLY n 1 942 ALA n 1 943 GLN n 1 944 GLY n 1 945 GLN n 1 946 PHE n 1 947 GLY n 1 948 GLY n 1 949 ASP n 1 950 HIS n 1 951 PRO n 1 952 SER n 1 953 ALA n 1 954 ARG n 1 955 GLU n 1 956 ASP n 1 957 LEU n 1 958 ASP n 1 959 VAL n 1 960 SER n 1 961 VAL n 1 962 MET n 1 963 ARG n 1 964 ARG n 1 965 LEU n 1 966 THR n 1 967 LYS n 1 968 SER n 1 969 SER n 1 970 ALA n 1 971 LYS n 1 972 THR n 1 973 GLN n 1 974 ARG n 1 975 VAL n 1 976 GLY n 1 977 TYR n 1 978 VAL n 1 979 LEU n 1 980 HIS n 1 981 ARG n 1 982 THR n 1 983 ASN n 1 984 LEU n 1 985 MET n 1 986 GLN n 1 987 CYS n 1 988 GLY n 1 989 THR n 1 990 PRO n 1 991 GLU n 1 992 GLU n 1 993 HIS n 1 994 THR n 1 995 GLN n 1 996 LYS n 1 997 LEU n 1 998 ASP n 1 999 VAL n 1 1000 CYS n 1 1001 HIS n 1 1002 LEU n 1 1003 LEU n 1 1004 PRO n 1 1005 ASN n 1 1006 VAL n 1 1007 ALA n 1 1008 ARG n 1 1009 CYS n 1 1010 GLU n 1 1011 ARG n 1 1012 THR n 1 1013 THR n 1 1014 LEU n 1 1015 THR n 1 1016 PHE n 1 1017 LEU n 1 1018 GLN n 1 1019 ASN n 1 1020 LEU n 1 1021 GLU n 1 1022 HIS n 1 1023 LEU n 1 1024 ASP n 1 1025 GLY n 1 1026 MET n 1 1027 VAL n 1 1028 ALA n 1 1029 PRO n 1 1030 GLU n 1 1031 VAL n 1 1032 CYS n 1 1033 PRO n 1 1034 MET n 1 1035 GLU n 1 1036 THR n 1 1037 ALA n 1 1038 ALA n 1 1039 TYR n 1 1040 VAL n 1 1041 SER n 1 1042 SER n 1 1043 HIS n 1 1044 SER n 1 1045 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'fruit fly' _entity_src_gen.gene_src_genus Drosophila _entity_src_gen.pdbx_gene_src_gene 'ALPHA-MAN-II OR GMII OR CG18474/CG18802/CG8139' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 7227 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'fruit fly' _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus Drosophila _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain S2 _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MAN2_DROME _struct_ref.pdbx_db_accession Q24451 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHND PGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEAN SHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWD NKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTN VLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSD NYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQE ALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFY VSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLL RKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPN GPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQ FIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIY RLVLEKVNNCVRPSELHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKT QRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS ; _struct_ref.pdbx_align_begin 76 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 1QWU _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 13 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 1045 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q24451 _struct_ref_seq.db_align_beg 76 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 1108 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 13 _struct_ref_seq.pdbx_auth_seq_align_end 1045 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 1QWU ARG A 1 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 1 1 1 1QWU SER A 2 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 2 2 1 1QWU SER A 3 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 3 3 1 1QWU HIS A 4 ? UNP Q24451 ? ? 'EXPRESSION TAG' 4 4 1 1QWU HIS A 5 ? UNP Q24451 ? ? 'EXPRESSION TAG' 5 5 1 1QWU HIS A 6 ? UNP Q24451 ? ? 'EXPRESSION TAG' 6 6 1 1QWU HIS A 7 ? UNP Q24451 ? ? 'EXPRESSION TAG' 7 7 1 1QWU HIS A 8 ? UNP Q24451 ? ? 'EXPRESSION TAG' 8 8 1 1QWU HIS A 9 ? UNP Q24451 ? ? 'EXPRESSION TAG' 9 9 1 1QWU GLY A 10 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 10 10 1 1QWU GLU A 11 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 11 11 1 1QWU PHE A 12 ? UNP Q24451 ? ? 'CLONING ARTIFACT' 12 12 1 1QWU ASN A 341 ? UNP Q24451 ASP 404 ENGINEERED 341 13 1 1QWU LYS A 907 ? UNP Q24451 GLU 970 'SEE REMARK 999' 907 14 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GUL non-polymer . '5-FLUORO-BETA-L-GULOSYL FLUORIDE' ? 'C6 H10 F2 O5' 200.137 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MPD non-polymer . '(4S)-2-METHYL-2,4-PENTANEDIOL' ? 'C6 H14 O2' 118.174 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 1QWU _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.19 _exptl_crystal.density_percent_sol 43.83 _exptl_crystal.description ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7 _exptl_crystal_grow.pdbx_details 'PEG 6000, MPD, Tris, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 298K' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector 'IMAGE PLATE' _diffrn_detector.type MARRESEARCH _diffrn_detector.pdbx_collection_date ? _diffrn_detector.details Osmic # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'focussing mirrors' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.5418 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source 'ROTATING ANODE' _diffrn_source.type 'RIGAKU RU200' _diffrn_source.pdbx_synchrotron_site ? _diffrn_source.pdbx_synchrotron_beamline ? _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.5418 # _reflns.entry_id 1QWU _reflns.observed_criterion_sigma_I 2.0 _reflns.observed_criterion_sigma_F 2.9 _reflns.d_resolution_low 20 _reflns.d_resolution_high 2.0 _reflns.number_obs 66355 _reflns.number_all 68690 _reflns.percent_possible_obs 96.6 _reflns.pdbx_Rmerge_I_obs 0.11 _reflns.pdbx_Rsym_value 0.11 _reflns.pdbx_netI_over_sigmaI 16.8 _reflns.B_iso_Wilson_estimate 7.5 _reflns.pdbx_redundancy 7 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 2.03 _reflns_shell.d_res_low 2.16 _reflns_shell.percent_possible_all 92.4 _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 10064 _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 1QWU _refine.ls_number_reflns_obs 66355 _refine.ls_number_reflns_all 68690 _refine.pdbx_ls_sigma_I 0.0 _refine.pdbx_ls_sigma_F 0.0 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 19.84 _refine.ls_d_res_high 2.03 _refine.ls_percent_reflns_obs 96.6 _refine.ls_R_factor_obs 0.151 _refine.ls_R_factor_all 0.16 _refine.ls_R_factor_R_work 0.151 _refine.ls_R_factor_R_free 0.189 _refine.ls_R_factor_R_free_error 0.004 _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 3.5 _refine.ls_number_reflns_R_free 2336 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 16.9 _refine.aniso_B[1][1] 0.28 _refine.aniso_B[2][2] 0.97 _refine.aniso_B[3][3] -1.25 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'FLAT MODEL' _refine.solvent_model_param_ksol 0.338431 _refine.solvent_model_param_bsol 46.5168 _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ? _refine.pdbx_starting_model 1HTY _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 1QWU _refine_analyze.Luzzati_coordinate_error_obs ? _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_coordinate_error_free 0.21 _refine_analyze.Luzzati_sigma_a_free 0.16 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8181 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 35 _refine_hist.number_atoms_solvent 1025 _refine_hist.number_atoms_total 9241 _refine_hist.d_res_high 2.03 _refine_hist.d_res_low 19.84 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d 0.015 ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg 1.7 ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d 24.9 ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d 1.07 ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it 1.08 1.50 ? ? 'X-RAY DIFFRACTION' ? c_mcangle_it 1.63 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scbond_it 1.79 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scangle_it 2.59 2.50 ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 6 _refine_ls_shell.d_res_high 2.03 _refine_ls_shell.d_res_low 2.16 _refine_ls_shell.number_reflns_R_work 10064 _refine_ls_shell.R_factor_R_work 0.181 _refine_ls_shell.percent_reflns_obs 92.4 _refine_ls_shell.R_factor_R_free 0.206 _refine_ls_shell.R_factor_R_free_error 0.011 _refine_ls_shell.percent_reflns_R_free 3.5 _refine_ls_shell.number_reflns_R_free 361 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.number_reflns_all ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.R_factor_all ? # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 PROTEIN_REP.PRO PROTEIN_REP.TOP 'X-RAY DIFFRACTION' 2 CARBOHYDRATE.PARAM CARBOHYDRATE.TOP 'X-RAY DIFFRACTION' 3 CIS_PEPTIDE.PARAM CIS_PEPTIDE.TOP 'X-RAY DIFFRACTION' 4 WATER_REP.PARAM WATER_REP.TOP 'X-RAY DIFFRACTION' 5 ION.PARAM ION.TOP 'X-RAY DIFFRACTION' # _struct.entry_id 1QWU _struct.title 'Golgi alpha-mannosidase II D341N mutant complex with 5-F-guloside' _struct.pdbx_descriptor 'Alpha-mannosidase II (E.C.3.2.1.114)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 1QWU _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'glycosyl hydrolase family 38, covalent catalytic intermediate, HYDROLASE' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 6 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 MET A 45 ? MET A 52 ? MET A 45 MET A 52 1 ? 8 HELX_P HELX_P2 2 ASP A 71 ? TYR A 75 ? ASP A 71 TYR A 75 5 ? 5 HELX_P HELX_P3 3 THR A 98 ? ASP A 106 ? THR A 98 ASP A 106 1 ? 9 HELX_P HELX_P4 4 ASP A 106 ? ASN A 121 ? ASP A 106 ASN A 121 1 ? 16 HELX_P HELX_P5 5 GLU A 130 ? LEU A 141 ? GLU A 130 LEU A 141 1 ? 12 HELX_P HELX_P6 6 GLY A 142 ? ASN A 155 ? GLY A 142 ASN A 155 1 ? 14 HELX_P HELX_P7 7 HIS A 174 ? ASN A 194 ? HIS A 174 ASN A 194 1 ? 21 HELX_P HELX_P8 8 PRO A 210 ? LYS A 218 ? PRO A 210 LYS A 218 1 ? 9 HELX_P HELX_P9 9 HIS A 230 ? GLN A 240 ? HIS A 230 GLN A 240 1 ? 11 HELX_P HELX_P10 10 ASP A 270 ? THR A 274 ? ASP A 270 THR A 274 5 ? 5 HELX_P HELX_P11 11 ASP A 278 ? CYS A 283 ? ASP A 278 CYS A 283 1 ? 6 HELX_P HELX_P12 12 GLN A 284 ? ASP A 286 ? GLN A 284 ASP A 286 5 ? 3 HELX_P HELX_P13 13 ASN A 310 ? GLU A 327 ? ASN A 310 GLU A 327 1 ? 18 HELX_P HELX_P14 14 GLN A 346 ? GLN A 367 ? GLN A 346 GLN A 367 1 ? 22 HELX_P HELX_P15 15 ALA A 368 ? PHE A 370 ? ALA A 368 PHE A 370 5 ? 3 HELX_P HELX_P16 16 THR A 378 ? ALA A 392 ? THR A 378 ALA A 392 1 ? 15 HELX_P HELX_P17 17 SER A 416 ? THR A 420 ? SER A 416 THR A 420 5 ? 5 HELX_P HELX_P18 18 ARG A 422 ? TRP A 445 ? ARG A 422 TRP A 445 1 ? 24 HELX_P HELX_P19 19 ASP A 449 ? ALA A 452 ? ASP A 449 ALA A 452 5 ? 4 HELX_P HELX_P20 20 ARG A 453 ? GLN A 469 ? ARG A 453 GLN A 469 1 ? 17 HELX_P HELX_P21 21 LYS A 479 ? LEU A 509 ? LYS A 479 LEU A 509 1 ? 31 HELX_P HELX_P22 22 PRO A 823 ? TYR A 828 ? PRO A 823 TYR A 828 5 ? 6 HELX_P HELX_P23 23 THR A 915 ? ASP A 927 ? THR A 915 ASP A 927 1 ? 13 HELX_P HELX_P24 24 ASP A 998 ? LEU A 1002 ? ASP A 998 LEU A 1002 5 ? 5 HELX_P HELX_P25 25 ASP A 1024 ? VAL A 1027 ? ASP A 1024 VAL A 1027 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 31 SG ? ? ? 1_555 A CYS 1032 SG ? ? A CYS 31 A CYS 1032 1_555 ? ? ? ? ? ? ? 2.020 ? disulf2 disulf ? ? A CYS 275 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 275 A CYS 282 1_555 ? ? ? ? ? ? ? 2.034 ? disulf3 disulf ? ? A CYS 283 SG ? ? ? 1_555 A CYS 297 SG ? ? A CYS 283 A CYS 297 1_555 ? ? ? ? ? ? ? 2.051 ? disulf4 disulf ? ? A CYS 902 SG ? ? ? 1_555 A CYS 987 SG ? ? A CYS 902 A CYS 987 1_555 ? ? ? ? ? ? ? 2.038 ? disulf5 disulf ? ? A CYS 1000 SG ? ? ? 1_555 A CYS 1009 SG ? ? A CYS 1000 A CYS 1009 1_555 ? ? ? ? ? ? ? 1.996 ? covale1 covale ? ? A ASN 194 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 194 A NAG 2001 1_555 ? ? ? ? ? ? ? 1.458 ? covale2 covale ? ? A ASP 204 OD1 ? ? ? 1_555 D GUL . C1 ? ? A ASP 204 A GUL 2003 1_555 ? ? ? ? ? ? ? 1.379 ? metalc1 metalc ? ? C ZN . ZN ? ? ? 1_555 A HIS 90 NE2 ? ? A ZN 2004 A HIS 90 1_555 ? ? ? ? ? ? ? 2.092 ? metalc2 metalc ? ? C ZN . ZN ? ? ? 1_555 D GUL . O2 ? ? A ZN 2004 A GUL 2003 1_555 ? ? ? ? ? ? ? 2.340 ? metalc3 metalc ? ? C ZN . ZN ? ? ? 1_555 A ASP 92 OD1 ? ? A ZN 2004 A ASP 92 1_555 ? ? ? ? ? ? ? 2.014 ? metalc4 metalc ? ? C ZN . ZN ? ? ? 1_555 A HIS 471 NE2 ? ? A ZN 2004 A HIS 471 1_555 ? ? ? ? ? ? ? 2.181 ? metalc5 metalc ? ? C ZN . ZN ? ? ? 1_555 D GUL . O3 ? ? A ZN 2004 A GUL 2003 1_555 ? ? ? ? ? ? ? 2.142 ? metalc6 metalc ? ? C ZN . ZN ? ? ? 1_555 A ASP 204 OD1 ? ? A ZN 2004 A ASP 204 1_555 ? ? ? ? ? ? ? 2.653 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 405 A . ? PHE 405 A THR 406 A ? THR 406 A 1 0.86 2 TRP 531 A . ? TRP 531 A PRO 532 A ? PRO 532 A 1 0.47 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 6 ? B ? 3 ? C ? 2 ? D ? 2 ? E ? 6 ? F ? 5 ? G ? 5 ? H ? 12 ? I ? 5 ? J ? 8 ? K ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? anti-parallel A 4 5 ? parallel A 5 6 ? parallel B 1 2 ? parallel B 2 3 ? parallel C 1 2 ? parallel D 1 2 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? anti-parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? parallel H 1 2 ? parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel H 6 7 ? anti-parallel H 7 8 ? anti-parallel H 8 9 ? anti-parallel H 9 10 ? anti-parallel H 10 11 ? anti-parallel H 11 12 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? anti-parallel J 6 7 ? anti-parallel J 7 8 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 VAL A 43 ? GLN A 44 ? VAL A 43 GLN A 44 A 2 THR A 399 ? SER A 401 ? THR A 399 SER A 401 A 3 GLU A 244 ? TRP A 247 ? GLU A 244 TRP A 247 A 4 LEU A 259 ? MET A 263 ? LEU A 259 MET A 263 A 5 ASN A 223 ? ILE A 226 ? ASN A 223 ILE A 226 A 6 ALA A 199 ? ALA A 202 ? ALA A 199 ALA A 202 B 1 VAL A 333 ? ASN A 341 ? VAL A 333 ASN A 341 B 2 LEU A 81 ? HIS A 90 ? LEU A 81 HIS A 90 B 3 VAL A 372 ? PHE A 376 ? VAL A 372 PHE A 376 C 1 PHE A 126 ? TRP A 128 ? PHE A 126 TRP A 128 C 2 LEU A 158 ? PHE A 160 ? LEU A 158 PHE A 160 D 1 ALA A 408 ? ARG A 410 ? ALA A 408 ARG A 410 D 2 ASN A 413 ? TYR A 414 ? ASN A 413 TYR A 414 E 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 E 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 E 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 E 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 E 5 VAL A 578 ? ASP A 582 ? VAL A 578 ASP A 582 E 6 PRO A 587 ? VAL A 588 ? PRO A 587 VAL A 588 F 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 F 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 F 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 F 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 F 5 GLN A 945 ? PHE A 946 ? GLN A 945 PHE A 946 G 1 THR A 542 ? ILE A 543 ? THR A 542 ILE A 543 G 2 ARG A 565 ? VAL A 573 ? ARG A 565 VAL A 573 G 3 THR A 606 ? VAL A 624 ? THR A 606 VAL A 624 G 4 ALA A 590 ? ASP A 601 ? ALA A 590 ASP A 601 G 5 THR A 644 ? TYR A 646 ? THR A 644 TYR A 646 H 1 LYS A 669 ? GLY A 671 ? LYS A 669 GLY A 671 H 2 SER A 648 ? LEU A 652 ? SER A 648 LEU A 652 H 3 VAL A 745 ? LYS A 749 ? VAL A 745 LYS A 749 H 4 SER A 754 ? LEU A 760 ? SER A 754 LEU A 760 H 5 VAL A 763 ? MET A 769 ? VAL A 763 MET A 769 H 6 GLU A 775 ? VAL A 780 ? GLU A 775 VAL A 780 H 7 VAL A 888 ? LYS A 898 ? VAL A 888 LYS A 898 H 8 THR A 842 ? THR A 848 ? THR A 842 THR A 848 H 9 GLY A 834 ? GLU A 838 ? GLY A 834 GLU A 838 H 10 ILE A 803 ? LEU A 808 ? ILE A 803 LEU A 808 H 11 GLN A 812 ? ARG A 817 ? GLN A 812 ARG A 817 H 12 ALA A 911 ? GLY A 912 ? ALA A 911 GLY A 912 I 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 I 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 I 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 I 4 VAL A 706 ? TYR A 715 ? VAL A 706 TYR A 715 I 5 SER A 736 ? PRO A 737 ? SER A 736 PRO A 737 J 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 J 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 J 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 J 4 VAL A 706 ? TYR A 715 ? VAL A 706 TYR A 715 J 5 THR A 788 ? THR A 796 ? THR A 788 THR A 796 J 6 GLU A 861 ? ARG A 869 ? GLU A 861 ARG A 869 J 7 LEU A 852 ? SER A 855 ? LEU A 852 SER A 855 J 8 TYR A 829 ? ILE A 831 ? TYR A 829 ILE A 831 K 1 LEU A 957 ? ARG A 964 ? LEU A 957 ARG A 964 K 2 GLN A 973 ? ARG A 981 ? GLN A 973 ARG A 981 K 3 THR A 1036 ? HIS A 1043 ? THR A 1036 HIS A 1043 K 4 VAL A 1006 ? THR A 1012 ? VAL A 1006 THR A 1012 K 5 ASN A 1019 ? HIS A 1022 ? ASN A 1019 HIS A 1022 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 43 ? N VAL A 43 O THR A 399 ? O THR A 399 A 2 3 O LEU A 400 ? O LEU A 400 N LEU A 246 ? N LEU A 246 A 3 4 N PHE A 245 ? N PHE A 245 O THR A 261 ? O THR A 261 A 4 5 O HIS A 262 ? O HIS A 262 N MET A 224 ? N MET A 224 A 5 6 O ASN A 223 ? O ASN A 223 N SER A 200 ? N SER A 200 B 1 2 O LEU A 334 ? O LEU A 334 N LYS A 82 ? N LYS A 82 B 2 3 N VAL A 83 ? N VAL A 83 O GLN A 373 ? O GLN A 373 C 1 2 N PHE A 126 ? N PHE A 126 O GLU A 159 ? O GLU A 159 D 1 2 N ARG A 410 ? N ARG A 410 O ASN A 413 ? O ASN A 413 E 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 E 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 E 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 E 4 5 O VAL A 633 ? O VAL A 633 N THR A 581 ? N THR A 581 E 5 6 N VAL A 580 ? N VAL A 580 O VAL A 588 ? O VAL A 588 F 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 F 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 F 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 F 4 5 N LEU A 629 ? N LEU A 629 O PHE A 946 ? O PHE A 946 G 1 2 N ILE A 543 ? N ILE A 543 O TYR A 572 ? O TYR A 572 G 2 3 N PHE A 571 ? N PHE A 571 O ILE A 618 ? O ILE A 618 G 3 4 O ILE A 619 ? O ILE A 619 N GLN A 591 ? N GLN A 591 G 4 5 N VAL A 592 ? N VAL A 592 O SER A 645 ? O SER A 645 H 1 2 O LYS A 669 ? O LYS A 669 N LEU A 651 ? N LEU A 651 H 2 3 N LEU A 652 ? N LEU A 652 O VAL A 745 ? O VAL A 745 H 3 4 N LEU A 746 ? N LEU A 746 O SER A 757 ? O SER A 757 H 4 5 N SER A 754 ? N SER A 754 O MET A 769 ? O MET A 769 H 5 6 N ILE A 768 ? N ILE A 768 O GLU A 775 ? O GLU A 775 H 6 7 N VAL A 780 ? N VAL A 780 O VAL A 888 ? O VAL A 888 H 7 8 O VAL A 895 ? O VAL A 895 N THR A 845 ? N THR A 845 H 8 9 O LEU A 846 ? O LEU A 846 N MET A 835 ? N MET A 835 H 9 10 O PHE A 836 ? O PHE A 836 N TYR A 805 ? N TYR A 805 H 10 11 N PHE A 804 ? N PHE A 804 O ARG A 816 ? O ARG A 816 H 11 12 N PHE A 813 ? N PHE A 813 O GLY A 912 ? O GLY A 912 I 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 I 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 I 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 I 4 5 N LYS A 714 ? N LYS A 714 O SER A 736 ? O SER A 736 J 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 J 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 J 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 J 4 5 N LYS A 711 ? N LYS A 711 O ARG A 793 ? O ARG A 793 J 5 6 N ILE A 790 ? N ILE A 790 O GLN A 866 ? O GLN A 866 J 6 7 O GLU A 863 ? O GLU A 863 N SER A 855 ? N SER A 855 J 7 8 O LEU A 852 ? O LEU A 852 N ILE A 831 ? N ILE A 831 K 1 2 N ARG A 963 ? N ARG A 963 O GLY A 976 ? O GLY A 976 K 2 3 N LEU A 979 ? N LEU A 979 O ALA A 1037 ? O ALA A 1037 K 3 4 O SER A 1042 ? O SER A 1042 N ARG A 1008 ? N ARG A 1008 K 4 5 N ARG A 1011 ? N ARG A 1011 O LEU A 1020 ? O LEU A 1020 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 2001' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE ZN A 2004' AC3 Software ? ? ? ? 14 'BINDING SITE FOR RESIDUE GUL A 2003' AC4 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE MPD A 2002' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 2 ASN A 194 ? ASN A 194 . ? 1_555 ? 2 AC1 2 HOH F . ? HOH A 2675 . ? 1_555 ? 3 AC2 5 HIS A 90 ? HIS A 90 . ? 1_555 ? 4 AC2 5 ASP A 92 ? ASP A 92 . ? 1_555 ? 5 AC2 5 ASP A 204 ? ASP A 204 . ? 1_555 ? 6 AC2 5 HIS A 471 ? HIS A 471 . ? 1_555 ? 7 AC2 5 GUL D . ? GUL A 2003 . ? 1_555 ? 8 AC3 14 HIS A 90 ? HIS A 90 . ? 1_555 ? 9 AC3 14 ASP A 92 ? ASP A 92 . ? 1_555 ? 10 AC3 14 TRP A 95 ? TRP A 95 . ? 1_555 ? 11 AC3 14 ASP A 204 ? ASP A 204 . ? 1_555 ? 12 AC3 14 PHE A 206 ? PHE A 206 . ? 1_555 ? 13 AC3 14 ARG A 228 ? ARG A 228 . ? 1_555 ? 14 AC3 14 TYR A 269 ? TYR A 269 . ? 1_555 ? 15 AC3 14 TRP A 415 ? TRP A 415 . ? 1_555 ? 16 AC3 14 HIS A 471 ? HIS A 471 . ? 1_555 ? 17 AC3 14 ASP A 472 ? ASP A 472 . ? 1_555 ? 18 AC3 14 TYR A 727 ? TYR A 727 . ? 1_555 ? 19 AC3 14 ARG A 876 ? ARG A 876 . ? 1_555 ? 20 AC3 14 ZN C . ? ZN A 2004 . ? 1_555 ? 21 AC3 14 HOH F . ? HOH A 2875 . ? 1_555 ? 22 AC4 7 LYS A 63 ? LYS A 63 . ? 1_555 ? 23 AC4 7 GLN A 64 ? GLN A 64 . ? 1_555 ? 24 AC4 7 HIS A 273 ? HIS A 273 . ? 1_555 ? 25 AC4 7 HOH F . ? HOH A 2153 . ? 1_555 ? 26 AC4 7 HOH F . ? HOH A 2621 . ? 1_555 ? 27 AC4 7 HOH F . ? HOH A 2695 . ? 1_555 ? 28 AC4 7 HOH F . ? HOH A 2843 . ? 1_555 ? # _database_PDB_matrix.entry_id 1QWU _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 1QWU _atom_sites.fract_transf_matrix[1][1] 0.014524 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009108 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007206 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C F N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . CYS A 1 31 ? 44.246 35.992 -18.713 1.00 21.89 ? 31 CYS A N 1 ATOM 2 C CA . CYS A 1 31 ? 43.510 37.305 -18.531 1.00 21.32 ? 31 CYS A CA 1 ATOM 3 C C . CYS A 1 31 ? 42.012 37.148 -18.688 1.00 21.56 ? 31 CYS A C 1 ATOM 4 O O . CYS A 1 31 ? 41.563 36.676 -19.729 1.00 21.31 ? 31 CYS A O 1 ATOM 5 C CB . CYS A 1 31 ? 43.900 38.359 -19.570 1.00 20.43 ? 31 CYS A CB 1 ATOM 6 S SG . CYS A 1 31 ? 45.530 39.142 -19.483 1.00 21.58 ? 31 CYS A SG 1 ATOM 7 N N . GLN A 1 32 ? 41.246 37.578 -17.683 1.00 21.32 ? 32 GLN A N 1 ATOM 8 C CA . GLN A 1 32 ? 39.780 37.533 -17.756 1.00 21.89 ? 32 GLN A CA 1 ATOM 9 C C . GLN A 1 32 ? 39.282 38.471 -18.870 1.00 20.75 ? 32 GLN A C 1 ATOM 10 O O . GLN A 1 32 ? 39.916 39.484 -19.214 1.00 19.43 ? 32 GLN A O 1 ATOM 11 C CB . GLN A 1 32 ? 39.127 38.037 -16.474 1.00 23.62 ? 32 GLN A CB 1 ATOM 12 C CG . GLN A 1 32 ? 39.174 37.171 -15.253 1.00 28.28 ? 32 GLN A CG 1 ATOM 13 C CD . GLN A 1 32 ? 38.170 37.677 -14.222 1.00 30.74 ? 32 GLN A CD 1 ATOM 14 O OE1 . GLN A 1 32 ? 36.978 37.354 -14.291 1.00 32.99 ? 32 GLN A OE1 1 ATOM 15 N NE2 . GLN A 1 32 ? 38.637 38.505 -13.284 1.00 31.66 ? 32 GLN A NE2 1 ATOM 16 N N . ASP A 1 33 ? 38.112 38.153 -19.385 1.00 19.83 ? 33 ASP A N 1 ATOM 17 C CA . ASP A 1 33 ? 37.492 38.934 -20.443 1.00 19.84 ? 33 ASP A CA 1 ATOM 18 C C . ASP A 1 33 ? 36.602 39.916 -19.678 1.00 18.83 ? 33 ASP A C 1 ATOM 19 O O . ASP A 1 33 ? 35.716 39.504 -18.946 1.00 20.74 ? 33 ASP A O 1 ATOM 20 C CB . ASP A 1 33 ? 36.674 37.990 -21.328 1.00 20.39 ? 33 ASP A CB 1 ATOM 21 C CG . ASP A 1 33 ? 36.030 38.690 -22.495 1.00 22.19 ? 33 ASP A CG 1 ATOM 22 O OD1 . ASP A 1 33 ? 35.911 38.056 -23.564 1.00 23.69 ? 33 ASP A OD1 1 ATOM 23 O OD2 . ASP A 1 33 ? 35.621 39.859 -22.354 1.00 22.31 ? 33 ASP A OD2 1 ATOM 24 N N . VAL A 1 34 ? 36.828 41.212 -19.841 1.00 15.85 ? 34 VAL A N 1 ATOM 25 C CA . VAL A 1 34 ? 36.067 42.175 -19.060 1.00 13.38 ? 34 VAL A CA 1 ATOM 26 C C . VAL A 1 34 ? 34.877 42.741 -19.812 1.00 13.99 ? 34 VAL A C 1 ATOM 27 O O . VAL A 1 34 ? 34.153 43.625 -19.315 1.00 11.91 ? 34 VAL A O 1 ATOM 28 C CB . VAL A 1 34 ? 37.000 43.308 -18.585 1.00 13.49 ? 34 VAL A CB 1 ATOM 29 C CG1 . VAL A 1 34 ? 38.210 42.700 -17.876 1.00 12.07 ? 34 VAL A CG1 1 ATOM 30 C CG2 . VAL A 1 34 ? 37.496 44.136 -19.768 1.00 11.56 ? 34 VAL A CG2 1 ATOM 31 N N . VAL A 1 35 ? 34.661 42.208 -21.010 1.00 12.04 ? 35 VAL A N 1 ATOM 32 C CA . VAL A 1 35 ? 33.581 42.675 -21.854 1.00 12.15 ? 35 VAL A CA 1 ATOM 33 C C . VAL A 1 35 ? 32.391 41.722 -22.026 1.00 12.74 ? 35 VAL A C 1 ATOM 34 O O . VAL A 1 35 ? 31.245 42.087 -21.789 1.00 12.85 ? 35 VAL A O 1 ATOM 35 C CB . VAL A 1 35 ? 34.126 42.993 -23.290 1.00 13.52 ? 35 VAL A CB 1 ATOM 36 C CG1 . VAL A 1 35 ? 32.966 43.426 -24.226 1.00 12.17 ? 35 VAL A CG1 1 ATOM 37 C CG2 . VAL A 1 35 ? 35.222 44.048 -23.218 1.00 10.31 ? 35 VAL A CG2 1 ATOM 38 N N . GLN A 1 36 ? 32.689 40.494 -22.414 1.00 14.70 ? 36 GLN A N 1 ATOM 39 C CA . GLN A 1 36 ? 31.685 39.487 -22.765 1.00 16.67 ? 36 GLN A CA 1 ATOM 40 C C . GLN A 1 36 ? 31.021 38.597 -21.750 1.00 18.73 ? 36 GLN A C 1 ATOM 41 O O . GLN A 1 36 ? 30.025 37.979 -22.067 1.00 21.00 ? 36 GLN A O 1 ATOM 42 C CB . GLN A 1 36 ? 32.284 38.612 -23.853 1.00 16.76 ? 36 GLN A CB 1 ATOM 43 C CG . GLN A 1 36 ? 32.946 39.472 -24.917 1.00 17.97 ? 36 GLN A CG 1 ATOM 44 C CD . GLN A 1 36 ? 33.459 38.672 -26.102 1.00 18.26 ? 36 GLN A CD 1 ATOM 45 O OE1 . GLN A 1 36 ? 32.733 38.432 -27.052 1.00 18.35 ? 36 GLN A OE1 1 ATOM 46 N NE2 . GLN A 1 36 ? 34.718 38.254 -26.038 1.00 17.97 ? 36 GLN A NE2 1 ATOM 47 N N . ASP A 1 37 ? 31.569 38.508 -20.548 1.00 20.46 ? 37 ASP A N 1 ATOM 48 C CA . ASP A 1 37 ? 30.996 37.675 -19.498 1.00 20.39 ? 37 ASP A CA 1 ATOM 49 C C . ASP A 1 37 ? 30.353 38.529 -18.410 1.00 19.60 ? 37 ASP A C 1 ATOM 50 O O . ASP A 1 37 ? 31.064 39.172 -17.658 1.00 20.99 ? 37 ASP A O 1 ATOM 51 C CB . ASP A 1 37 ? 32.100 36.842 -18.841 1.00 22.32 ? 37 ASP A CB 1 ATOM 52 C CG . ASP A 1 37 ? 32.783 35.907 -19.812 1.00 24.17 ? 37 ASP A CG 1 ATOM 53 O OD1 . ASP A 1 37 ? 32.071 35.264 -20.608 1.00 24.80 ? 37 ASP A OD1 1 ATOM 54 O OD2 . ASP A 1 37 ? 34.027 35.824 -19.773 1.00 26.59 ? 37 ASP A OD2 1 ATOM 55 N N . VAL A 1 38 ? 29.032 38.525 -18.311 1.00 18.84 ? 38 VAL A N 1 ATOM 56 C CA . VAL A 1 38 ? 28.348 39.287 -17.268 1.00 18.46 ? 38 VAL A CA 1 ATOM 57 C C . VAL A 1 38 ? 28.533 38.582 -15.896 1.00 17.92 ? 38 VAL A C 1 ATOM 58 O O . VAL A 1 38 ? 28.058 37.463 -15.700 1.00 16.98 ? 38 VAL A O 1 ATOM 59 C CB . VAL A 1 38 ? 26.837 39.379 -17.564 1.00 19.47 ? 38 VAL A CB 1 ATOM 60 C CG1 . VAL A 1 38 ? 26.105 40.126 -16.432 1.00 20.00 ? 38 VAL A CG1 1 ATOM 61 C CG2 . VAL A 1 38 ? 26.617 40.093 -18.922 1.00 19.53 ? 38 VAL A CG2 1 ATOM 62 N N . PRO A 1 39 ? 29.241 39.227 -14.946 1.00 16.52 ? 39 PRO A N 1 ATOM 63 C CA . PRO A 1 39 ? 29.410 38.571 -13.649 1.00 15.58 ? 39 PRO A CA 1 ATOM 64 C C . PRO A 1 39 ? 28.083 38.218 -12.996 1.00 16.58 ? 39 PRO A C 1 ATOM 65 O O . PRO A 1 39 ? 27.072 38.932 -13.106 1.00 15.22 ? 39 PRO A O 1 ATOM 66 C CB . PRO A 1 39 ? 30.190 39.600 -12.829 1.00 16.45 ? 39 PRO A CB 1 ATOM 67 C CG . PRO A 1 39 ? 31.074 40.285 -13.876 1.00 15.63 ? 39 PRO A CG 1 ATOM 68 C CD . PRO A 1 39 ? 30.086 40.444 -15.047 1.00 16.34 ? 39 PRO A CD 1 ATOM 69 N N . ASN A 1 40 ? 28.093 37.090 -12.302 1.00 18.11 ? 40 ASN A N 1 ATOM 70 C CA . ASN A 1 40 ? 26.927 36.631 -11.589 1.00 19.04 ? 40 ASN A CA 1 ATOM 71 C C . ASN A 1 40 ? 27.098 37.006 -10.100 1.00 17.60 ? 40 ASN A C 1 ATOM 72 O O . ASN A 1 40 ? 27.925 36.421 -9.400 1.00 17.83 ? 40 ASN A O 1 ATOM 73 C CB . ASN A 1 40 ? 26.812 35.119 -11.733 1.00 23.38 ? 40 ASN A CB 1 ATOM 74 C CG . ASN A 1 40 ? 25.569 34.586 -11.075 1.00 28.15 ? 40 ASN A CG 1 ATOM 75 O OD1 . ASN A 1 40 ? 24.454 34.847 -11.528 1.00 32.63 ? 40 ASN A OD1 1 ATOM 76 N ND2 . ASN A 1 40 ? 25.744 33.856 -9.986 1.00 31.45 ? 40 ASN A ND2 1 ATOM 77 N N . VAL A 1 41 ? 26.322 37.957 -9.601 1.00 15.25 ? 41 VAL A N 1 ATOM 78 C CA . VAL A 1 41 ? 26.472 38.360 -8.193 1.00 14.16 ? 41 VAL A CA 1 ATOM 79 C C . VAL A 1 41 ? 25.124 38.408 -7.493 1.00 13.07 ? 41 VAL A C 1 ATOM 80 O O . VAL A 1 41 ? 24.105 38.588 -8.135 1.00 13.39 ? 41 VAL A O 1 ATOM 81 C CB . VAL A 1 41 ? 27.137 39.755 -8.098 1.00 14.12 ? 41 VAL A CB 1 ATOM 82 C CG1 . VAL A 1 41 ? 28.595 39.672 -8.515 1.00 13.61 ? 41 VAL A CG1 1 ATOM 83 C CG2 . VAL A 1 41 ? 26.394 40.736 -9.015 1.00 13.39 ? 41 VAL A CG2 1 ATOM 84 N N . ASP A 1 42 ? 25.111 38.235 -6.180 1.00 12.35 ? 42 ASP A N 1 ATOM 85 C CA . ASP A 1 42 ? 23.864 38.287 -5.442 1.00 11.59 ? 42 ASP A CA 1 ATOM 86 C C . ASP A 1 42 ? 23.210 39.671 -5.469 1.00 12.16 ? 42 ASP A C 1 ATOM 87 O O . ASP A 1 42 ? 21.982 39.790 -5.498 1.00 11.77 ? 42 ASP A O 1 ATOM 88 C CB . ASP A 1 42 ? 24.129 37.859 -3.999 1.00 14.12 ? 42 ASP A CB 1 ATOM 89 C CG . ASP A 1 42 ? 24.729 36.473 -3.923 1.00 12.75 ? 42 ASP A CG 1 ATOM 90 O OD1 . ASP A 1 42 ? 24.118 35.558 -4.500 1.00 14.67 ? 42 ASP A OD1 1 ATOM 91 O OD2 . ASP A 1 42 ? 25.802 36.298 -3.326 1.00 13.34 ? 42 ASP A OD2 1 ATOM 92 N N . VAL A 1 43 ? 24.015 40.730 -5.421 1.00 11.08 ? 43 VAL A N 1 ATOM 93 C CA . VAL A 1 43 ? 23.465 42.096 -5.455 1.00 10.87 ? 43 VAL A CA 1 ATOM 94 C C . VAL A 1 43 ? 24.206 42.886 -6.540 1.00 11.04 ? 43 VAL A C 1 ATOM 95 O O . VAL A 1 43 ? 25.437 42.952 -6.503 1.00 9.91 ? 43 VAL A O 1 ATOM 96 C CB . VAL A 1 43 ? 23.707 42.825 -4.094 1.00 12.87 ? 43 VAL A CB 1 ATOM 97 C CG1 . VAL A 1 43 ? 23.143 44.276 -4.132 1.00 10.96 ? 43 VAL A CG1 1 ATOM 98 C CG2 . VAL A 1 43 ? 23.100 41.994 -2.932 1.00 13.95 ? 43 VAL A CG2 1 ATOM 99 N N . GLN A 1 44 ? 23.491 43.428 -7.523 1.00 10.11 ? 44 GLN A N 1 ATOM 100 C CA . GLN A 1 44 ? 24.150 44.233 -8.557 1.00 10.43 ? 44 GLN A CA 1 ATOM 101 C C . GLN A 1 44 ? 23.433 45.563 -8.395 1.00 10.12 ? 44 GLN A C 1 ATOM 102 O O . GLN A 1 44 ? 22.233 45.657 -8.647 1.00 9.78 ? 44 GLN A O 1 ATOM 103 C CB . GLN A 1 44 ? 23.962 43.608 -9.956 1.00 11.25 ? 44 GLN A CB 1 ATOM 104 C CG . GLN A 1 44 ? 25.085 44.011 -10.967 1.00 9.69 ? 44 GLN A CG 1 ATOM 105 C CD . GLN A 1 44 ? 25.204 45.534 -11.077 1.00 10.22 ? 44 GLN A CD 1 ATOM 106 O OE1 . GLN A 1 44 ? 24.234 46.204 -11.376 1.00 9.98 ? 44 GLN A OE1 1 ATOM 107 N NE2 . GLN A 1 44 ? 26.393 46.076 -10.811 1.00 8.26 ? 44 GLN A NE2 1 ATOM 108 N N . MET A 1 45 ? 24.158 46.599 -7.966 1.00 9.39 ? 45 MET A N 1 ATOM 109 C CA . MET A 1 45 ? 23.501 47.855 -7.650 1.00 9.67 ? 45 MET A CA 1 ATOM 110 C C . MET A 1 45 ? 22.609 48.519 -8.678 1.00 9.38 ? 45 MET A C 1 ATOM 111 O O . MET A 1 45 ? 21.611 49.117 -8.307 1.00 9.26 ? 45 MET A O 1 ATOM 112 C CB . MET A 1 45 ? 24.507 48.857 -7.067 1.00 9.76 ? 45 MET A CB 1 ATOM 113 C CG . MET A 1 45 ? 25.093 48.413 -5.732 1.00 9.75 ? 45 MET A CG 1 ATOM 114 S SD . MET A 1 45 ? 23.897 48.100 -4.448 1.00 13.34 ? 45 MET A SD 1 ATOM 115 C CE . MET A 1 45 ? 23.179 49.717 -4.262 1.00 10.79 ? 45 MET A CE 1 ATOM 116 N N . LEU A 1 46 ? 22.938 48.429 -9.958 1.00 9.71 ? 46 LEU A N 1 ATOM 117 C CA . LEU A 1 46 ? 22.064 49.039 -10.972 1.00 11.02 ? 46 LEU A CA 1 ATOM 118 C C . LEU A 1 46 ? 20.724 48.256 -11.007 1.00 12.45 ? 46 LEU A C 1 ATOM 119 O O . LEU A 1 46 ? 19.640 48.841 -11.135 1.00 12.28 ? 46 LEU A O 1 ATOM 120 C CB . LEU A 1 46 ? 22.725 48.986 -12.370 1.00 9.00 ? 46 LEU A CB 1 ATOM 121 C CG . LEU A 1 46 ? 21.923 49.672 -13.486 1.00 8.37 ? 46 LEU A CG 1 ATOM 122 C CD1 . LEU A 1 46 ? 21.961 51.196 -13.272 1.00 10.05 ? 46 LEU A CD1 1 ATOM 123 C CD2 . LEU A 1 46 ? 22.511 49.301 -14.851 1.00 8.35 ? 46 LEU A CD2 1 ATOM 124 N N . GLU A 1 47 ? 20.829 46.929 -10.883 1.00 13.53 ? 47 GLU A N 1 ATOM 125 C CA . GLU A 1 47 ? 19.662 46.063 -10.913 1.00 14.85 ? 47 GLU A CA 1 ATOM 126 C C . GLU A 1 47 ? 18.819 46.345 -9.691 1.00 14.47 ? 47 GLU A C 1 ATOM 127 O O . GLU A 1 47 ? 17.589 46.513 -9.794 1.00 14.96 ? 47 GLU A O 1 ATOM 128 C CB . GLU A 1 47 ? 20.091 44.602 -10.962 1.00 17.74 ? 47 GLU A CB 1 ATOM 129 C CG . GLU A 1 47 ? 18.970 43.579 -11.210 1.00 22.19 ? 47 GLU A CG 1 ATOM 130 C CD . GLU A 1 47 ? 18.125 43.266 -9.974 1.00 24.52 ? 47 GLU A CD 1 ATOM 131 O OE1 . GLU A 1 47 ? 18.593 43.447 -8.831 1.00 24.82 ? 47 GLU A OE1 1 ATOM 132 O OE2 . GLU A 1 47 ? 16.979 42.806 -10.148 1.00 28.00 ? 47 GLU A OE2 1 ATOM 133 N N . LEU A 1 48 ? 19.476 46.463 -8.541 1.00 13.44 ? 48 LEU A N 1 ATOM 134 C CA . LEU A 1 48 ? 18.759 46.753 -7.309 1.00 12.87 ? 48 LEU A CA 1 ATOM 135 C C . LEU A 1 48 ? 18.024 48.085 -7.441 1.00 12.29 ? 48 LEU A C 1 ATOM 136 O O . LEU A 1 48 ? 16.842 48.198 -7.102 1.00 11.79 ? 48 LEU A O 1 ATOM 137 C CB . LEU A 1 48 ? 19.726 46.785 -6.127 1.00 13.86 ? 48 LEU A CB 1 ATOM 138 C CG . LEU A 1 48 ? 19.101 46.936 -4.725 1.00 16.55 ? 48 LEU A CG 1 ATOM 139 C CD1 . LEU A 1 48 ? 18.107 45.776 -4.456 1.00 16.84 ? 48 LEU A CD1 1 ATOM 140 C CD2 . LEU A 1 48 ? 20.176 46.972 -3.659 1.00 15.00 ? 48 LEU A CD2 1 ATOM 141 N N . TYR A 1 49 ? 18.701 49.090 -7.981 1.00 11.49 ? 49 TYR A N 1 ATOM 142 C CA . TYR A 1 49 ? 18.100 50.414 -8.137 1.00 11.63 ? 49 TYR A CA 1 ATOM 143 C C . TYR A 1 49 ? 16.834 50.372 -9.007 1.00 12.96 ? 49 TYR A C 1 ATOM 144 O O . TYR A 1 49 ? 15.859 51.076 -8.746 1.00 11.14 ? 49 TYR A O 1 ATOM 145 C CB . TYR A 1 49 ? 19.133 51.378 -8.760 1.00 10.36 ? 49 TYR A CB 1 ATOM 146 C CG . TYR A 1 49 ? 19.744 52.297 -7.733 1.00 10.69 ? 49 TYR A CG 1 ATOM 147 C CD1 . TYR A 1 49 ? 20.245 51.796 -6.512 1.00 9.23 ? 49 TYR A CD1 1 ATOM 148 C CD2 . TYR A 1 49 ? 19.723 53.673 -7.932 1.00 8.12 ? 49 TYR A CD2 1 ATOM 149 C CE1 . TYR A 1 49 ? 20.695 52.663 -5.514 1.00 10.62 ? 49 TYR A CE1 1 ATOM 150 C CE2 . TYR A 1 49 ? 20.160 54.542 -6.941 1.00 11.66 ? 49 TYR A CE2 1 ATOM 151 C CZ . TYR A 1 49 ? 20.634 54.045 -5.741 1.00 9.37 ? 49 TYR A CZ 1 ATOM 152 O OH . TYR A 1 49 ? 20.936 54.947 -4.759 1.00 11.25 ? 49 TYR A OH 1 ATOM 153 N N . ASP A 1 50 ? 16.874 49.543 -10.039 1.00 14.94 ? 50 ASP A N 1 ATOM 154 C CA . ASP A 1 50 ? 15.759 49.395 -10.964 1.00 17.41 ? 50 ASP A CA 1 ATOM 155 C C . ASP A 1 50 ? 14.513 48.853 -10.222 1.00 19.10 ? 50 ASP A C 1 ATOM 156 O O . ASP A 1 50 ? 13.389 49.308 -10.459 1.00 17.85 ? 50 ASP A O 1 ATOM 157 C CB . ASP A 1 50 ? 16.174 48.421 -12.070 1.00 18.75 ? 50 ASP A CB 1 ATOM 158 C CG . ASP A 1 50 ? 15.373 48.577 -13.336 1.00 22.13 ? 50 ASP A CG 1 ATOM 159 O OD1 . ASP A 1 50 ? 15.436 47.650 -14.181 1.00 22.95 ? 50 ASP A OD1 1 ATOM 160 O OD2 . ASP A 1 50 ? 14.703 49.615 -13.503 1.00 24.11 ? 50 ASP A OD2 1 ATOM 161 N N . ARG A 1 51 ? 14.716 47.889 -9.326 1.00 20.06 ? 51 ARG A N 1 ATOM 162 C CA . ARG A 1 51 ? 13.591 47.292 -8.602 1.00 22.60 ? 51 ARG A CA 1 ATOM 163 C C . ARG A 1 51 ? 13.113 48.037 -7.354 1.00 22.33 ? 51 ARG A C 1 ATOM 164 O O . ARG A 1 51 ? 11.925 48.001 -7.044 1.00 22.35 ? 51 ARG A O 1 ATOM 165 C CB . ARG A 1 51 ? 13.888 45.843 -8.179 1.00 25.94 ? 51 ARG A CB 1 ATOM 166 C CG . ARG A 1 51 ? 15.040 45.163 -8.857 1.00 30.31 ? 51 ARG A CG 1 ATOM 167 C CD . ARG A 1 51 ? 15.006 43.672 -8.520 1.00 33.76 ? 51 ARG A CD 1 ATOM 168 N NE . ARG A 1 51 ? 14.942 43.479 -7.085 1.00 35.54 ? 51 ARG A NE 1 ATOM 169 C CZ . ARG A 1 51 ? 15.988 43.254 -6.296 1.00 35.95 ? 51 ARG A CZ 1 ATOM 170 N NH1 . ARG A 1 51 ? 17.211 43.174 -6.791 1.00 37.28 ? 51 ARG A NH1 1 ATOM 171 N NH2 . ARG A 1 51 ? 15.800 43.133 -4.990 1.00 36.96 ? 51 ARG A NH2 1 ATOM 172 N N . MET A 1 52 ? 14.025 48.701 -6.648 1.00 21.62 ? 52 MET A N 1 ATOM 173 C CA . MET A 1 52 ? 13.700 49.422 -5.421 1.00 22.09 ? 52 MET A CA 1 ATOM 174 C C . MET A 1 52 ? 12.706 50.551 -5.613 1.00 22.07 ? 52 MET A C 1 ATOM 175 O O . MET A 1 52 ? 12.739 51.258 -6.626 1.00 22.62 ? 52 MET A O 1 ATOM 176 C CB . MET A 1 52 ? 14.969 50.022 -4.808 1.00 22.56 ? 52 MET A CB 1 ATOM 177 C CG . MET A 1 52 ? 15.848 49.045 -4.089 1.00 23.79 ? 52 MET A CG 1 ATOM 178 S SD . MET A 1 52 ? 17.385 49.899 -3.557 1.00 25.04 ? 52 MET A SD 1 ATOM 179 C CE . MET A 1 52 ? 16.721 51.175 -2.486 1.00 24.21 ? 52 MET A CE 1 ATOM 180 N N . SER A 1 53 ? 11.846 50.739 -4.620 1.00 21.53 ? 53 SER A N 1 ATOM 181 C CA . SER A 1 53 ? 10.838 51.793 -4.678 1.00 21.79 ? 53 SER A CA 1 ATOM 182 C C . SER A 1 53 ? 11.294 53.120 -4.091 1.00 20.91 ? 53 SER A C 1 ATOM 183 O O . SER A 1 53 ? 10.747 54.163 -4.442 1.00 20.26 ? 53 SER A O 1 ATOM 184 C CB . SER A 1 53 ? 9.565 51.349 -3.959 1.00 22.33 ? 53 SER A CB 1 ATOM 185 O OG . SER A 1 53 ? 8.906 50.371 -4.744 1.00 24.56 ? 53 SER A OG 1 ATOM 186 N N . PHE A 1 54 ? 12.265 53.073 -3.180 1.00 19.11 ? 54 PHE A N 1 ATOM 187 C CA . PHE A 1 54 ? 12.771 54.286 -2.563 1.00 19.21 ? 54 PHE A CA 1 ATOM 188 C C . PHE A 1 54 ? 11.724 55.058 -1.776 1.00 20.38 ? 54 PHE A C 1 ATOM 189 O O . PHE A 1 54 ? 11.835 56.286 -1.655 1.00 20.35 ? 54 PHE A O 1 ATOM 190 C CB . PHE A 1 54 ? 13.380 55.225 -3.633 1.00 17.10 ? 54 PHE A CB 1 ATOM 191 C CG . PHE A 1 54 ? 14.643 54.692 -4.260 1.00 14.69 ? 54 PHE A CG 1 ATOM 192 C CD1 . PHE A 1 54 ? 14.585 53.783 -5.322 1.00 14.65 ? 54 PHE A CD1 1 ATOM 193 C CD2 . PHE A 1 54 ? 15.890 55.068 -3.760 1.00 13.78 ? 54 PHE A CD2 1 ATOM 194 C CE1 . PHE A 1 54 ? 15.758 53.256 -5.874 1.00 14.95 ? 54 PHE A CE1 1 ATOM 195 C CE2 . PHE A 1 54 ? 17.082 54.550 -4.300 1.00 12.75 ? 54 PHE A CE2 1 ATOM 196 C CZ . PHE A 1 54 ? 17.025 53.645 -5.356 1.00 14.70 ? 54 PHE A CZ 1 ATOM 197 N N . LYS A 1 55 ? 10.702 54.382 -1.235 1.00 20.01 ? 55 LYS A N 1 ATOM 198 C CA . LYS A 1 55 ? 9.686 55.128 -0.477 1.00 20.10 ? 55 LYS A CA 1 ATOM 199 C C . LYS A 1 55 ? 10.251 55.589 0.855 1.00 18.97 ? 55 LYS A C 1 ATOM 200 O O . LYS A 1 55 ? 10.851 54.808 1.570 1.00 20.50 ? 55 LYS A O 1 ATOM 201 C CB . LYS A 1 55 ? 8.432 54.267 -0.248 1.00 21.01 ? 55 LYS A CB 1 ATOM 202 C CG . LYS A 1 55 ? 7.788 53.840 -1.530 1.00 21.06 ? 55 LYS A CG 1 ATOM 203 C CD . LYS A 1 55 ? 7.487 55.026 -2.450 1.00 19.63 ? 55 LYS A CD 1 ATOM 204 C CE . LYS A 1 55 ? 6.934 54.471 -3.758 1.00 20.44 ? 55 LYS A CE 1 ATOM 205 N NZ . LYS A 1 55 ? 6.172 55.465 -4.568 1.00 19.21 ? 55 LYS A NZ 1 ATOM 206 N N . ASP A 1 56 ? 10.048 56.851 1.194 1.00 18.09 ? 56 ASP A N 1 ATOM 207 C CA . ASP A 1 56 ? 10.596 57.407 2.441 1.00 18.49 ? 56 ASP A CA 1 ATOM 208 C C . ASP A 1 56 ? 9.533 57.383 3.562 1.00 19.36 ? 56 ASP A C 1 ATOM 209 O O . ASP A 1 56 ? 8.978 58.413 3.924 1.00 19.09 ? 56 ASP A O 1 ATOM 210 C CB . ASP A 1 56 ? 11.088 58.841 2.147 1.00 16.95 ? 56 ASP A CB 1 ATOM 211 C CG . ASP A 1 56 ? 11.720 59.526 3.344 1.00 16.93 ? 56 ASP A CG 1 ATOM 212 O OD1 . ASP A 1 56 ? 12.234 58.858 4.260 1.00 17.09 ? 56 ASP A OD1 1 ATOM 213 O OD2 . ASP A 1 56 ? 11.717 60.763 3.366 1.00 18.77 ? 56 ASP A OD2 1 ATOM 214 N N . ILE A 1 57 ? 9.251 56.214 4.116 1.00 20.01 ? 57 ILE A N 1 ATOM 215 C CA . ILE A 1 57 ? 8.244 56.149 5.155 1.00 21.79 ? 57 ILE A CA 1 ATOM 216 C C . ILE A 1 57 ? 8.852 56.152 6.540 1.00 21.46 ? 57 ILE A C 1 ATOM 217 O O . ILE A 1 57 ? 10.000 55.748 6.736 1.00 21.75 ? 57 ILE A O 1 ATOM 218 C CB . ILE A 1 57 ? 7.323 54.888 4.987 1.00 25.03 ? 57 ILE A CB 1 ATOM 219 C CG1 . ILE A 1 57 ? 8.063 53.639 5.391 1.00 25.11 ? 57 ILE A CG1 1 ATOM 220 C CG2 . ILE A 1 57 ? 6.864 54.697 3.527 1.00 23.63 ? 57 ILE A CG2 1 ATOM 221 C CD1 . ILE A 1 57 ? 7.512 53.118 6.649 1.00 29.03 ? 57 ILE A CD1 1 ATOM 222 N N . ASP A 1 58 ? 8.072 56.627 7.503 1.00 21.82 ? 58 ASP A N 1 ATOM 223 C CA . ASP A 1 58 ? 8.479 56.686 8.907 1.00 21.46 ? 58 ASP A CA 1 ATOM 224 C C . ASP A 1 58 ? 8.503 55.272 9.460 1.00 20.96 ? 58 ASP A C 1 ATOM 225 O O . ASP A 1 58 ? 7.451 54.638 9.585 1.00 22.16 ? 58 ASP A O 1 ATOM 226 C CB . ASP A 1 58 ? 7.474 57.511 9.675 1.00 21.36 ? 58 ASP A CB 1 ATOM 227 C CG . ASP A 1 58 ? 7.863 57.696 11.112 1.00 22.74 ? 58 ASP A CG 1 ATOM 228 O OD1 . ASP A 1 58 ? 7.274 58.601 11.749 1.00 25.60 ? 58 ASP A OD1 1 ATOM 229 O OD2 . ASP A 1 58 ? 8.742 56.959 11.610 1.00 22.14 ? 58 ASP A OD2 1 ATOM 230 N N . GLY A 1 59 ? 9.687 54.758 9.774 1.00 19.13 ? 59 GLY A N 1 ATOM 231 C CA . GLY A 1 59 ? 9.771 53.397 10.278 1.00 17.43 ? 59 GLY A CA 1 ATOM 232 C C . GLY A 1 59 ? 9.777 53.291 11.795 1.00 16.35 ? 59 GLY A C 1 ATOM 233 O O . GLY A 1 59 ? 10.061 52.223 12.324 1.00 16.19 ? 59 GLY A O 1 ATOM 234 N N . GLY A 1 60 ? 9.459 54.391 12.479 1.00 16.56 ? 60 GLY A N 1 ATOM 235 C CA . GLY A 1 60 ? 9.443 54.417 13.943 1.00 16.23 ? 60 GLY A CA 1 ATOM 236 C C . GLY A 1 60 ? 10.699 55.027 14.540 1.00 16.20 ? 60 GLY A C 1 ATOM 237 O O . GLY A 1 60 ? 11.253 55.979 13.997 1.00 15.33 ? 60 GLY A O 1 ATOM 238 N N . VAL A 1 61 ? 11.160 54.502 15.672 1.00 16.33 ? 61 VAL A N 1 ATOM 239 C CA . VAL A 1 61 ? 12.366 55.038 16.269 1.00 16.28 ? 61 VAL A CA 1 ATOM 240 C C . VAL A 1 61 ? 13.495 54.908 15.233 1.00 16.42 ? 61 VAL A C 1 ATOM 241 O O . VAL A 1 61 ? 14.352 55.801 15.134 1.00 16.21 ? 61 VAL A O 1 ATOM 242 C CB . VAL A 1 61 ? 12.718 54.327 17.589 1.00 15.90 ? 61 VAL A CB 1 ATOM 243 C CG1 . VAL A 1 61 ? 11.679 54.728 18.682 1.00 15.97 ? 61 VAL A CG1 1 ATOM 244 C CG2 . VAL A 1 61 ? 12.734 52.806 17.402 1.00 16.29 ? 61 VAL A CG2 1 ATOM 245 N N . TRP A 1 62 ? 13.513 53.810 14.468 1.00 15.15 ? 62 TRP A N 1 ATOM 246 C CA . TRP A 1 62 ? 14.504 53.715 13.403 1.00 15.25 ? 62 TRP A CA 1 ATOM 247 C C . TRP A 1 62 ? 13.723 54.370 12.270 1.00 16.82 ? 62 TRP A C 1 ATOM 248 O O . TRP A 1 62 ? 13.016 53.712 11.498 1.00 15.83 ? 62 TRP A O 1 ATOM 249 C CB . TRP A 1 62 ? 14.863 52.265 13.055 1.00 13.71 ? 62 TRP A CB 1 ATOM 250 C CG . TRP A 1 62 ? 15.917 52.163 11.962 1.00 14.85 ? 62 TRP A CG 1 ATOM 251 C CD1 . TRP A 1 62 ? 16.593 53.209 11.364 1.00 15.32 ? 62 TRP A CD1 1 ATOM 252 C CD2 . TRP A 1 62 ? 16.313 50.981 11.259 1.00 14.85 ? 62 TRP A CD2 1 ATOM 253 N NE1 . TRP A 1 62 ? 17.364 52.742 10.320 1.00 16.57 ? 62 TRP A NE1 1 ATOM 254 C CE2 . TRP A 1 62 ? 17.218 51.381 10.235 1.00 15.25 ? 62 TRP A CE2 1 ATOM 255 C CE3 . TRP A 1 62 ? 15.991 49.624 11.388 1.00 13.62 ? 62 TRP A CE3 1 ATOM 256 C CZ2 . TRP A 1 62 ? 17.795 50.468 9.343 1.00 15.46 ? 62 TRP A CZ2 1 ATOM 257 C CZ3 . TRP A 1 62 ? 16.563 48.716 10.504 1.00 14.25 ? 62 TRP A CZ3 1 ATOM 258 C CH2 . TRP A 1 62 ? 17.456 49.141 9.492 1.00 15.82 ? 62 TRP A CH2 1 ATOM 259 N N . LYS A 1 63 ? 13.840 55.696 12.192 1.00 17.65 ? 63 LYS A N 1 ATOM 260 C CA . LYS A 1 63 ? 13.114 56.482 11.201 1.00 18.19 ? 63 LYS A CA 1 ATOM 261 C C . LYS A 1 63 ? 13.144 55.977 9.756 1.00 17.26 ? 63 LYS A C 1 ATOM 262 O O . LYS A 1 63 ? 12.148 56.068 9.030 1.00 17.94 ? 63 LYS A O 1 ATOM 263 C CB . LYS A 1 63 ? 13.600 57.939 11.260 1.00 18.75 ? 63 LYS A CB 1 ATOM 264 C CG . LYS A 1 63 ? 13.075 58.745 12.495 1.00 22.70 ? 63 LYS A CG 1 ATOM 265 C CD . LYS A 1 63 ? 11.568 59.057 12.356 1.00 24.73 ? 63 LYS A CD 1 ATOM 266 C CE . LYS A 1 63 ? 10.935 59.705 13.584 1.00 26.79 ? 63 LYS A CE 1 ATOM 267 N NZ . LYS A 1 63 ? 11.126 59.003 14.922 1.00 29.35 ? 63 LYS A NZ 1 ATOM 268 N N . GLN A 1 64 ? 14.278 55.446 9.323 1.00 15.67 ? 64 GLN A N 1 ATOM 269 C CA . GLN A 1 64 ? 14.380 54.986 7.937 1.00 14.50 ? 64 GLN A CA 1 ATOM 270 C C . GLN A 1 64 ? 14.398 53.477 7.768 1.00 13.54 ? 64 GLN A C 1 ATOM 271 O O . GLN A 1 64 ? 14.683 52.968 6.683 1.00 12.04 ? 64 GLN A O 1 ATOM 272 C CB . GLN A 1 64 ? 15.602 55.639 7.280 1.00 13.77 ? 64 GLN A CB 1 ATOM 273 C CG . GLN A 1 64 ? 15.490 57.168 7.307 1.00 13.17 ? 64 GLN A CG 1 ATOM 274 C CD . GLN A 1 64 ? 16.837 57.856 7.144 1.00 13.81 ? 64 GLN A CD 1 ATOM 275 O OE1 . GLN A 1 64 ? 17.817 57.507 7.829 1.00 13.33 ? 64 GLN A OE1 1 ATOM 276 N NE2 . GLN A 1 64 ? 16.898 58.826 6.228 1.00 12.59 ? 64 GLN A NE2 1 ATOM 277 N N . GLY A 1 65 ? 14.056 52.772 8.838 1.00 13.57 ? 65 GLY A N 1 ATOM 278 C CA . GLY A 1 65 ? 14.014 51.319 8.768 1.00 15.56 ? 65 GLY A CA 1 ATOM 279 C C . GLY A 1 65 ? 12.639 50.774 9.165 1.00 17.04 ? 65 GLY A C 1 ATOM 280 O O . GLY A 1 65 ? 11.623 51.121 8.531 1.00 18.36 ? 65 GLY A O 1 ATOM 281 N N . TRP A 1 66 ? 12.605 49.940 10.208 1.00 17.21 ? 66 TRP A N 1 ATOM 282 C CA . TRP A 1 66 ? 11.356 49.318 10.721 1.00 17.88 ? 66 TRP A CA 1 ATOM 283 C C . TRP A 1 66 ? 11.665 48.894 12.156 1.00 18.53 ? 66 TRP A C 1 ATOM 284 O O . TRP A 1 66 ? 12.834 48.977 12.557 1.00 18.86 ? 66 TRP A O 1 ATOM 285 C CB . TRP A 1 66 ? 11.015 48.071 9.903 1.00 16.95 ? 66 TRP A CB 1 ATOM 286 C CG . TRP A 1 66 ? 11.986 46.946 10.096 1.00 15.57 ? 66 TRP A CG 1 ATOM 287 C CD1 . TRP A 1 66 ? 11.871 45.897 10.962 1.00 15.09 ? 66 TRP A CD1 1 ATOM 288 C CD2 . TRP A 1 66 ? 13.207 46.730 9.369 1.00 15.94 ? 66 TRP A CD2 1 ATOM 289 N NE1 . TRP A 1 66 ? 12.933 45.032 10.815 1.00 13.68 ? 66 TRP A NE1 1 ATOM 290 C CE2 . TRP A 1 66 ? 13.771 45.520 9.849 1.00 15.46 ? 66 TRP A CE2 1 ATOM 291 C CE3 . TRP A 1 66 ? 13.877 47.440 8.355 1.00 16.10 ? 66 TRP A CE3 1 ATOM 292 C CZ2 . TRP A 1 66 ? 14.981 45.002 9.351 1.00 16.56 ? 66 TRP A CZ2 1 ATOM 293 C CZ3 . TRP A 1 66 ? 15.080 46.926 7.857 1.00 16.71 ? 66 TRP A CZ3 1 ATOM 294 C CH2 . TRP A 1 66 ? 15.621 45.722 8.356 1.00 16.46 ? 66 TRP A CH2 1 ATOM 295 N N . ASN A 1 67 ? 10.653 48.458 12.925 1.00 19.46 ? 67 ASN A N 1 ATOM 296 C CA . ASN A 1 67 ? 10.876 48.003 14.313 1.00 19.33 ? 67 ASN A CA 1 ATOM 297 C C . ASN A 1 67 ? 11.484 46.613 14.305 1.00 18.41 ? 67 ASN A C 1 ATOM 298 O O . ASN A 1 67 ? 10.811 45.608 13.997 1.00 16.24 ? 67 ASN A O 1 ATOM 299 C CB . ASN A 1 67 ? 9.577 47.970 15.142 1.00 22.45 ? 67 ASN A CB 1 ATOM 300 C CG . ASN A 1 67 ? 8.959 49.346 15.325 1.00 24.56 ? 67 ASN A CG 1 ATOM 301 O OD1 . ASN A 1 67 ? 9.657 50.351 15.501 1.00 26.09 ? 67 ASN A OD1 1 ATOM 302 N ND2 . ASN A 1 67 ? 7.638 49.394 15.300 1.00 27.27 ? 67 ASN A ND2 1 ATOM 303 N N . ILE A 1 68 ? 12.760 46.544 14.653 1.00 16.81 ? 68 ILE A N 1 ATOM 304 C CA . ILE A 1 68 ? 13.453 45.270 14.624 1.00 17.50 ? 68 ILE A CA 1 ATOM 305 C C . ILE A 1 68 ? 12.986 44.373 15.757 1.00 19.40 ? 68 ILE A C 1 ATOM 306 O O . ILE A 1 68 ? 12.845 44.813 16.891 1.00 18.16 ? 68 ILE A O 1 ATOM 307 C CB . ILE A 1 68 ? 14.991 45.470 14.745 1.00 17.59 ? 68 ILE A CB 1 ATOM 308 C CG1 . ILE A 1 68 ? 15.502 46.357 13.582 1.00 18.19 ? 68 ILE A CG1 1 ATOM 309 C CG2 . ILE A 1 68 ? 15.710 44.080 14.734 1.00 18.12 ? 68 ILE A CG2 1 ATOM 310 C CD1 . ILE A 1 68 ? 16.932 46.862 13.728 1.00 17.68 ? 68 ILE A CD1 1 ATOM 311 N N . LYS A 1 69 ? 12.741 43.107 15.451 1.00 21.03 ? 69 LYS A N 1 ATOM 312 C CA . LYS A 1 69 ? 12.329 42.166 16.490 1.00 23.19 ? 69 LYS A CA 1 ATOM 313 C C . LYS A 1 69 ? 13.352 41.047 16.455 1.00 22.37 ? 69 LYS A C 1 ATOM 314 O O . LYS A 1 69 ? 13.960 40.800 15.425 1.00 22.07 ? 69 LYS A O 1 ATOM 315 C CB . LYS A 1 69 ? 10.913 41.628 16.208 1.00 25.72 ? 69 LYS A CB 1 ATOM 316 C CG . LYS A 1 69 ? 9.798 42.661 16.497 1.00 29.02 ? 69 LYS A CG 1 ATOM 317 C CD . LYS A 1 69 ? 8.476 42.288 15.795 1.00 32.31 ? 69 LYS A CD 1 ATOM 318 C CE . LYS A 1 69 ? 8.148 40.777 15.943 1.00 34.94 ? 69 LYS A CE 1 ATOM 319 N NZ . LYS A 1 69 ? 6.884 40.336 15.216 1.00 36.49 ? 69 LYS A NZ 1 ATOM 320 N N . TYR A 1 70 ? 13.598 40.420 17.598 1.00 21.64 ? 70 TYR A N 1 ATOM 321 C CA . TYR A 1 70 ? 14.531 39.308 17.633 1.00 21.66 ? 70 TYR A CA 1 ATOM 322 C C . TYR A 1 70 ? 13.970 38.244 18.567 1.00 22.34 ? 70 TYR A C 1 ATOM 323 O O . TYR A 1 70 ? 13.105 38.531 19.402 1.00 21.96 ? 70 TYR A O 1 ATOM 324 C CB . TYR A 1 70 ? 15.926 39.754 18.106 1.00 19.77 ? 70 TYR A CB 1 ATOM 325 C CG . TYR A 1 70 ? 15.973 40.365 19.488 1.00 18.15 ? 70 TYR A CG 1 ATOM 326 C CD1 . TYR A 1 70 ? 16.198 39.589 20.613 1.00 19.06 ? 70 TYR A CD1 1 ATOM 327 C CD2 . TYR A 1 70 ? 15.802 41.721 19.660 1.00 17.74 ? 70 TYR A CD2 1 ATOM 328 C CE1 . TYR A 1 70 ? 16.258 40.168 21.880 1.00 18.47 ? 70 TYR A CE1 1 ATOM 329 C CE2 . TYR A 1 70 ? 15.848 42.305 20.907 1.00 18.10 ? 70 TYR A CE2 1 ATOM 330 C CZ . TYR A 1 70 ? 16.073 41.532 22.006 1.00 17.60 ? 70 TYR A CZ 1 ATOM 331 O OH . TYR A 1 70 ? 16.071 42.145 23.231 1.00 18.28 ? 70 TYR A OH 1 ATOM 332 N N . ASP A 1 71 ? 14.455 37.024 18.407 1.00 23.06 ? 71 ASP A N 1 ATOM 333 C CA . ASP A 1 71 ? 14.031 35.919 19.243 1.00 24.38 ? 71 ASP A CA 1 ATOM 334 C C . ASP A 1 71 ? 15.034 35.849 20.378 1.00 25.04 ? 71 ASP A C 1 ATOM 335 O O . ASP A 1 71 ? 16.197 35.526 20.172 1.00 25.21 ? 71 ASP A O 1 ATOM 336 C CB . ASP A 1 71 ? 14.038 34.635 18.431 1.00 26.39 ? 71 ASP A CB 1 ATOM 337 C CG . ASP A 1 71 ? 13.821 33.403 19.285 1.00 29.12 ? 71 ASP A CG 1 ATOM 338 O OD1 . ASP A 1 71 ? 13.284 33.522 20.417 1.00 30.00 ? 71 ASP A OD1 1 ATOM 339 O OD2 . ASP A 1 71 ? 14.195 32.314 18.809 1.00 30.41 ? 71 ASP A OD2 1 ATOM 340 N N . PRO A 1 72 ? 14.593 36.164 21.609 1.00 26.29 ? 72 PRO A N 1 ATOM 341 C CA . PRO A 1 72 ? 15.536 36.119 22.729 1.00 26.00 ? 72 PRO A CA 1 ATOM 342 C C . PRO A 1 72 ? 16.284 34.808 22.896 1.00 26.05 ? 72 PRO A C 1 ATOM 343 O O . PRO A 1 72 ? 17.387 34.790 23.440 1.00 26.99 ? 72 PRO A O 1 ATOM 344 C CB . PRO A 1 72 ? 14.675 36.504 23.947 1.00 25.93 ? 72 PRO A CB 1 ATOM 345 C CG . PRO A 1 72 ? 13.299 36.135 23.554 1.00 27.72 ? 72 PRO A CG 1 ATOM 346 C CD . PRO A 1 72 ? 13.224 36.466 22.062 1.00 25.26 ? 72 PRO A CD 1 ATOM 347 N N . LEU A 1 73 ? 15.718 33.719 22.398 1.00 25.40 ? 73 LEU A N 1 ATOM 348 C CA . LEU A 1 73 ? 16.371 32.428 22.528 1.00 25.71 ? 73 LEU A CA 1 ATOM 349 C C . LEU A 1 73 ? 17.458 32.221 21.508 1.00 25.63 ? 73 LEU A C 1 ATOM 350 O O . LEU A 1 73 ? 18.113 31.188 21.506 1.00 24.84 ? 73 LEU A O 1 ATOM 351 C CB . LEU A 1 73 ? 15.346 31.293 22.413 1.00 26.18 ? 73 LEU A CB 1 ATOM 352 C CG . LEU A 1 73 ? 14.320 31.374 23.560 1.00 27.56 ? 73 LEU A CG 1 ATOM 353 C CD1 . LEU A 1 73 ? 13.326 30.202 23.457 1.00 28.28 ? 73 LEU A CD1 1 ATOM 354 C CD2 . LEU A 1 73 ? 15.062 31.367 24.923 1.00 26.80 ? 73 LEU A CD2 1 ATOM 355 N N . LYS A 1 74 ? 17.663 33.198 20.630 1.00 25.10 ? 74 LYS A N 1 ATOM 356 C CA . LYS A 1 74 ? 18.697 33.027 19.619 1.00 25.34 ? 74 LYS A CA 1 ATOM 357 C C . LYS A 1 74 ? 20.070 32.840 20.266 1.00 25.26 ? 74 LYS A C 1 ATOM 358 O O . LYS A 1 74 ? 20.886 32.048 19.792 1.00 24.72 ? 74 LYS A O 1 ATOM 359 C CB . LYS A 1 74 ? 18.704 34.225 18.666 1.00 25.54 ? 74 LYS A CB 1 ATOM 360 C CG . LYS A 1 74 ? 19.666 34.098 17.485 1.00 27.10 ? 74 LYS A CG 1 ATOM 361 C CD . LYS A 1 74 ? 19.399 35.197 16.459 1.00 28.42 ? 74 LYS A CD 1 ATOM 362 C CE . LYS A 1 74 ? 20.415 35.166 15.341 1.00 29.23 ? 74 LYS A CE 1 ATOM 363 N NZ . LYS A 1 74 ? 20.006 36.131 14.283 1.00 30.12 ? 74 LYS A NZ 1 ATOM 364 N N . TYR A 1 75 ? 20.331 33.562 21.352 1.00 25.89 ? 75 TYR A N 1 ATOM 365 C CA . TYR A 1 75 ? 21.616 33.438 22.028 1.00 26.58 ? 75 TYR A CA 1 ATOM 366 C C . TYR A 1 75 ? 21.466 32.659 23.311 1.00 26.90 ? 75 TYR A C 1 ATOM 367 O O . TYR A 1 75 ? 20.463 32.789 23.996 1.00 27.17 ? 75 TYR A O 1 ATOM 368 C CB . TYR A 1 75 ? 22.197 34.812 22.329 1.00 27.00 ? 75 TYR A CB 1 ATOM 369 C CG . TYR A 1 75 ? 22.413 35.590 21.077 1.00 28.06 ? 75 TYR A CG 1 ATOM 370 C CD1 . TYR A 1 75 ? 21.504 36.564 20.687 1.00 29.23 ? 75 TYR A CD1 1 ATOM 371 C CD2 . TYR A 1 75 ? 23.480 35.303 20.237 1.00 28.15 ? 75 TYR A CD2 1 ATOM 372 C CE1 . TYR A 1 75 ? 21.643 37.236 19.499 1.00 29.33 ? 75 TYR A CE1 1 ATOM 373 C CE2 . TYR A 1 75 ? 23.626 35.969 19.035 1.00 30.82 ? 75 TYR A CE2 1 ATOM 374 C CZ . TYR A 1 75 ? 22.692 36.938 18.685 1.00 29.49 ? 75 TYR A CZ 1 ATOM 375 O OH . TYR A 1 75 ? 22.809 37.634 17.520 1.00 33.69 ? 75 TYR A OH 1 ATOM 376 N N . ASN A 1 76 ? 22.471 31.855 23.628 1.00 26.55 ? 76 ASN A N 1 ATOM 377 C CA . ASN A 1 76 ? 22.445 31.048 24.833 1.00 27.87 ? 76 ASN A CA 1 ATOM 378 C C . ASN A 1 76 ? 23.878 30.755 25.231 1.00 28.67 ? 76 ASN A C 1 ATOM 379 O O . ASN A 1 76 ? 24.807 31.187 24.557 1.00 29.25 ? 76 ASN A O 1 ATOM 380 C CB . ASN A 1 76 ? 21.674 29.746 24.591 1.00 27.45 ? 76 ASN A CB 1 ATOM 381 C CG . ASN A 1 76 ? 22.166 29.006 23.381 1.00 27.62 ? 76 ASN A CG 1 ATOM 382 O OD1 . ASN A 1 76 ? 23.344 28.660 23.282 1.00 28.38 ? 76 ASN A OD1 1 ATOM 383 N ND2 . ASN A 1 76 ? 21.262 28.761 22.436 1.00 29.84 ? 76 ASN A ND2 1 ATOM 384 N N . ALA A 1 77 ? 24.063 30.018 26.321 1.00 29.68 ? 77 ALA A N 1 ATOM 385 C CA . ALA A 1 77 ? 25.407 29.719 26.801 1.00 30.70 ? 77 ALA A CA 1 ATOM 386 C C . ALA A 1 77 ? 26.317 29.105 25.737 1.00 31.24 ? 77 ALA A C 1 ATOM 387 O O . ALA A 1 77 ? 27.528 29.269 25.777 1.00 31.88 ? 77 ALA A O 1 ATOM 388 C CB . ALA A 1 77 ? 25.324 28.806 28.015 1.00 30.79 ? 77 ALA A CB 1 ATOM 389 N N . HIS A 1 78 ? 25.737 28.416 24.767 1.00 32.65 ? 78 HIS A N 1 ATOM 390 C CA . HIS A 1 78 ? 26.545 27.779 23.727 1.00 33.77 ? 78 HIS A CA 1 ATOM 391 C C . HIS A 1 78 ? 26.648 28.600 22.453 1.00 32.69 ? 78 HIS A C 1 ATOM 392 O O . HIS A 1 78 ? 27.307 28.196 21.491 1.00 33.21 ? 78 HIS A O 1 ATOM 393 C CB . HIS A 1 78 ? 25.973 26.396 23.431 1.00 36.67 ? 78 HIS A CB 1 ATOM 394 C CG . HIS A 1 78 ? 25.770 25.583 24.667 1.00 40.28 ? 78 HIS A CG 1 ATOM 395 N ND1 . HIS A 1 78 ? 26.822 25.174 25.462 1.00 42.03 ? 78 HIS A ND1 1 ATOM 396 C CD2 . HIS A 1 78 ? 24.638 25.219 25.319 1.00 41.53 ? 78 HIS A CD2 1 ATOM 397 C CE1 . HIS A 1 78 ? 26.346 24.598 26.554 1.00 42.60 ? 78 HIS A CE1 1 ATOM 398 N NE2 . HIS A 1 78 ? 25.024 24.614 26.492 1.00 42.85 ? 78 HIS A NE2 1 ATOM 399 N N . HIS A 1 79 ? 26.004 29.763 22.463 1.00 30.64 ? 79 HIS A N 1 ATOM 400 C CA . HIS A 1 79 ? 26.039 30.659 21.325 1.00 27.32 ? 79 HIS A CA 1 ATOM 401 C C . HIS A 1 79 ? 25.804 32.066 21.832 1.00 24.52 ? 79 HIS A C 1 ATOM 402 O O . HIS A 1 79 ? 24.673 32.527 21.890 1.00 23.68 ? 79 HIS A O 1 ATOM 403 C CB . HIS A 1 79 ? 24.958 30.287 20.316 1.00 28.41 ? 79 HIS A CB 1 ATOM 404 C CG . HIS A 1 79 ? 25.044 31.068 19.043 1.00 29.74 ? 79 HIS A CG 1 ATOM 405 N ND1 . HIS A 1 79 ? 24.185 32.103 18.744 1.00 30.07 ? 79 HIS A ND1 1 ATOM 406 C CD2 . HIS A 1 79 ? 25.928 31.002 18.021 1.00 28.79 ? 79 HIS A CD2 1 ATOM 407 C CE1 . HIS A 1 79 ? 24.540 32.645 17.593 1.00 29.82 ? 79 HIS A CE1 1 ATOM 408 N NE2 . HIS A 1 79 ? 25.595 31.994 17.135 1.00 28.91 ? 79 HIS A NE2 1 ATOM 409 N N . LYS A 1 80 ? 26.878 32.737 22.205 1.00 20.98 ? 80 LYS A N 1 ATOM 410 C CA . LYS A 1 80 ? 26.775 34.090 22.728 1.00 19.94 ? 80 LYS A CA 1 ATOM 411 C C . LYS A 1 80 ? 27.025 35.169 21.666 1.00 18.53 ? 80 LYS A C 1 ATOM 412 O O . LYS A 1 80 ? 27.649 34.911 20.646 1.00 16.54 ? 80 LYS A O 1 ATOM 413 C CB . LYS A 1 80 ? 27.790 34.280 23.844 1.00 21.70 ? 80 LYS A CB 1 ATOM 414 C CG . LYS A 1 80 ? 27.592 33.323 24.999 1.00 23.85 ? 80 LYS A CG 1 ATOM 415 C CD . LYS A 1 80 ? 28.777 33.348 25.925 1.00 26.43 ? 80 LYS A CD 1 ATOM 416 C CE . LYS A 1 80 ? 28.888 34.655 26.666 1.00 28.44 ? 80 LYS A CE 1 ATOM 417 N NZ . LYS A 1 80 ? 29.712 34.444 27.909 1.00 30.51 ? 80 LYS A NZ 1 ATOM 418 N N . LEU A 1 81 ? 26.537 36.371 21.946 1.00 16.69 ? 81 LEU A N 1 ATOM 419 C CA . LEU A 1 81 ? 26.735 37.517 21.092 1.00 15.41 ? 81 LEU A CA 1 ATOM 420 C C . LEU A 1 81 ? 28.045 38.163 21.595 1.00 16.46 ? 81 LEU A C 1 ATOM 421 O O . LEU A 1 81 ? 28.155 38.601 22.758 1.00 14.99 ? 81 LEU A O 1 ATOM 422 C CB . LEU A 1 81 ? 25.556 38.501 21.241 1.00 14.38 ? 81 LEU A CB 1 ATOM 423 C CG . LEU A 1 81 ? 25.667 39.763 20.348 1.00 13.01 ? 81 LEU A CG 1 ATOM 424 C CD1 . LEU A 1 81 ? 25.587 39.339 18.886 1.00 12.32 ? 81 LEU A CD1 1 ATOM 425 C CD2 . LEU A 1 81 ? 24.511 40.742 20.637 1.00 12.20 ? 81 LEU A CD2 1 ATOM 426 N N . LYS A 1 82 ? 29.044 38.188 20.730 1.00 15.65 ? 82 LYS A N 1 ATOM 427 C CA . LYS A 1 82 ? 30.341 38.771 21.039 1.00 16.37 ? 82 LYS A CA 1 ATOM 428 C C . LYS A 1 82 ? 30.249 40.229 20.569 1.00 16.33 ? 82 LYS A C 1 ATOM 429 O O . LYS A 1 82 ? 30.079 40.488 19.374 1.00 15.15 ? 82 LYS A O 1 ATOM 430 C CB . LYS A 1 82 ? 31.406 38.026 20.237 1.00 19.43 ? 82 LYS A CB 1 ATOM 431 C CG . LYS A 1 82 ? 32.798 37.999 20.843 1.00 24.82 ? 82 LYS A CG 1 ATOM 432 C CD . LYS A 1 82 ? 33.079 39.146 21.809 1.00 27.96 ? 82 LYS A CD 1 ATOM 433 C CE . LYS A 1 82 ? 34.558 39.127 22.239 1.00 30.21 ? 82 LYS A CE 1 ATOM 434 N NZ . LYS A 1 82 ? 35.011 37.822 22.798 1.00 31.59 ? 82 LYS A NZ 1 ATOM 435 N N . VAL A 1 83 ? 30.398 41.180 21.492 1.00 14.58 ? 83 VAL A N 1 ATOM 436 C CA . VAL A 1 83 ? 30.248 42.590 21.139 1.00 12.76 ? 83 VAL A CA 1 ATOM 437 C C . VAL A 1 83 ? 31.572 43.341 21.260 1.00 13.60 ? 83 VAL A C 1 ATOM 438 O O . VAL A 1 83 ? 32.230 43.284 22.309 1.00 12.31 ? 83 VAL A O 1 ATOM 439 C CB . VAL A 1 83 ? 29.189 43.273 22.092 1.00 13.53 ? 83 VAL A CB 1 ATOM 440 C CG1 . VAL A 1 83 ? 28.973 44.759 21.725 1.00 12.80 ? 83 VAL A CG1 1 ATOM 441 C CG2 . VAL A 1 83 ? 27.858 42.527 22.002 1.00 12.83 ? 83 VAL A CG2 1 ATOM 442 N N . PHE A 1 84 ? 31.962 44.039 20.191 1.00 12.61 ? 84 PHE A N 1 ATOM 443 C CA . PHE A 1 84 ? 33.182 44.845 20.212 1.00 12.28 ? 84 PHE A CA 1 ATOM 444 C C . PHE A 1 84 ? 32.815 46.331 20.145 1.00 11.94 ? 84 PHE A C 1 ATOM 445 O O . PHE A 1 84 ? 32.278 46.804 19.145 1.00 10.95 ? 84 PHE A O 1 ATOM 446 C CB . PHE A 1 84 ? 34.081 44.504 19.025 1.00 12.60 ? 84 PHE A CB 1 ATOM 447 C CG . PHE A 1 84 ? 34.758 43.183 19.149 1.00 13.70 ? 84 PHE A CG 1 ATOM 448 C CD1 . PHE A 1 84 ? 34.358 42.118 18.378 1.00 14.41 ? 84 PHE A CD1 1 ATOM 449 C CD2 . PHE A 1 84 ? 35.794 43.006 20.076 1.00 13.53 ? 84 PHE A CD2 1 ATOM 450 C CE1 . PHE A 1 84 ? 34.977 40.874 18.513 1.00 15.05 ? 84 PHE A CE1 1 ATOM 451 C CE2 . PHE A 1 84 ? 36.422 41.779 20.230 1.00 13.87 ? 84 PHE A CE2 1 ATOM 452 C CZ . PHE A 1 84 ? 36.015 40.697 19.443 1.00 14.59 ? 84 PHE A CZ 1 ATOM 453 N N . VAL A 1 85 ? 33.107 47.059 21.208 1.00 10.80 ? 85 VAL A N 1 ATOM 454 C CA . VAL A 1 85 ? 32.838 48.503 21.250 1.00 10.62 ? 85 VAL A CA 1 ATOM 455 C C . VAL A 1 85 ? 34.146 49.133 20.815 1.00 9.97 ? 85 VAL A C 1 ATOM 456 O O . VAL A 1 85 ? 35.159 48.982 21.494 1.00 10.64 ? 85 VAL A O 1 ATOM 457 C CB . VAL A 1 85 ? 32.479 48.948 22.664 1.00 10.08 ? 85 VAL A CB 1 ATOM 458 C CG1 . VAL A 1 85 ? 32.335 50.481 22.730 1.00 9.10 ? 85 VAL A CG1 1 ATOM 459 C CG2 . VAL A 1 85 ? 31.175 48.209 23.088 1.00 9.29 ? 85 VAL A CG2 1 ATOM 460 N N . VAL A 1 86 ? 34.111 49.836 19.690 1.00 8.94 ? 86 VAL A N 1 ATOM 461 C CA . VAL A 1 86 ? 35.322 50.411 19.134 1.00 8.17 ? 86 VAL A CA 1 ATOM 462 C C . VAL A 1 86 ? 35.411 51.943 19.218 1.00 7.85 ? 86 VAL A C 1 ATOM 463 O O . VAL A 1 86 ? 34.817 52.653 18.445 1.00 8.26 ? 86 VAL A O 1 ATOM 464 C CB . VAL A 1 86 ? 35.490 49.939 17.635 1.00 10.08 ? 86 VAL A CB 1 ATOM 465 C CG1 . VAL A 1 86 ? 36.850 50.407 17.069 1.00 8.17 ? 86 VAL A CG1 1 ATOM 466 C CG2 . VAL A 1 86 ? 35.371 48.418 17.528 1.00 8.06 ? 86 VAL A CG2 1 ATOM 467 N N . PRO A 1 87 ? 36.179 52.458 20.177 1.00 8.19 ? 87 PRO A N 1 ATOM 468 C CA . PRO A 1 87 ? 36.346 53.913 20.345 1.00 7.30 ? 87 PRO A CA 1 ATOM 469 C C . PRO A 1 87 ? 37.035 54.533 19.125 1.00 8.70 ? 87 PRO A C 1 ATOM 470 O O . PRO A 1 87 ? 38.004 53.962 18.583 1.00 8.00 ? 87 PRO A O 1 ATOM 471 C CB . PRO A 1 87 ? 37.217 54.030 21.597 1.00 8.59 ? 87 PRO A CB 1 ATOM 472 C CG . PRO A 1 87 ? 36.896 52.688 22.352 1.00 7.25 ? 87 PRO A CG 1 ATOM 473 C CD . PRO A 1 87 ? 36.884 51.696 21.227 1.00 6.68 ? 87 PRO A CD 1 ATOM 474 N N . HIS A 1 88 ? 36.572 55.714 18.729 1.00 8.68 ? 88 HIS A N 1 ATOM 475 C CA . HIS A 1 88 ? 37.133 56.405 17.570 1.00 9.56 ? 88 HIS A CA 1 ATOM 476 C C . HIS A 1 88 ? 36.840 57.899 17.647 1.00 9.29 ? 88 HIS A C 1 ATOM 477 O O . HIS A 1 88 ? 35.994 58.348 18.429 1.00 8.41 ? 88 HIS A O 1 ATOM 478 C CB . HIS A 1 88 ? 36.564 55.814 16.264 1.00 9.66 ? 88 HIS A CB 1 ATOM 479 C CG . HIS A 1 88 ? 35.114 56.119 16.037 1.00 11.10 ? 88 HIS A CG 1 ATOM 480 N ND1 . HIS A 1 88 ? 34.687 57.212 15.311 1.00 11.47 ? 88 HIS A ND1 1 ATOM 481 C CD2 . HIS A 1 88 ? 33.992 55.469 16.434 1.00 11.93 ? 88 HIS A CD2 1 ATOM 482 C CE1 . HIS A 1 88 ? 33.367 57.217 15.261 1.00 11.21 ? 88 HIS A CE1 1 ATOM 483 N NE2 . HIS A 1 88 ? 32.918 56.170 15.935 1.00 12.41 ? 88 HIS A NE2 1 ATOM 484 N N . SER A 1 89 ? 37.563 58.668 16.840 1.00 9.07 ? 89 SER A N 1 ATOM 485 C CA . SER A 1 89 ? 37.413 60.122 16.819 1.00 8.99 ? 89 SER A CA 1 ATOM 486 C C . SER A 1 89 ? 37.572 60.551 15.360 1.00 9.19 ? 89 SER A C 1 ATOM 487 O O . SER A 1 89 ? 38.627 60.341 14.777 1.00 9.55 ? 89 SER A O 1 ATOM 488 C CB . SER A 1 89 ? 38.523 60.725 17.684 1.00 8.09 ? 89 SER A CB 1 ATOM 489 O OG . SER A 1 89 ? 38.491 62.127 17.658 1.00 10.10 ? 89 SER A OG 1 ATOM 490 N N . HIS A 1 90 ? 36.526 61.124 14.767 1.00 9.04 ? 90 HIS A N 1 ATOM 491 C CA . HIS A 1 90 ? 36.601 61.536 13.366 1.00 9.36 ? 90 HIS A CA 1 ATOM 492 C C . HIS A 1 90 ? 37.249 62.911 13.274 1.00 10.76 ? 90 HIS A C 1 ATOM 493 O O . HIS A 1 90 ? 36.671 63.928 13.702 1.00 10.65 ? 90 HIS A O 1 ATOM 494 C CB . HIS A 1 90 ? 35.203 61.555 12.713 1.00 8.59 ? 90 HIS A CB 1 ATOM 495 C CG . HIS A 1 90 ? 35.233 61.861 11.254 1.00 7.15 ? 90 HIS A CG 1 ATOM 496 N ND1 . HIS A 1 90 ? 35.813 61.019 10.331 1.00 8.88 ? 90 HIS A ND1 1 ATOM 497 C CD2 . HIS A 1 90 ? 34.811 62.946 10.562 1.00 6.58 ? 90 HIS A CD2 1 ATOM 498 C CE1 . HIS A 1 90 ? 35.747 61.566 9.129 1.00 9.10 ? 90 HIS A CE1 1 ATOM 499 N NE2 . HIS A 1 90 ? 35.143 62.736 9.243 1.00 7.56 ? 90 HIS A NE2 1 ATOM 500 N N . ASN A 1 91 ? 38.462 62.933 12.734 1.00 9.55 ? 91 ASN A N 1 ATOM 501 C CA . ASN A 1 91 ? 39.219 64.173 12.598 1.00 10.14 ? 91 ASN A CA 1 ATOM 502 C C . ASN A 1 91 ? 39.344 64.584 11.137 1.00 10.94 ? 91 ASN A C 1 ATOM 503 O O . ASN A 1 91 ? 39.820 63.794 10.305 1.00 11.20 ? 91 ASN A O 1 ATOM 504 C CB . ASN A 1 91 ? 40.630 63.984 13.174 1.00 9.77 ? 91 ASN A CB 1 ATOM 505 C CG . ASN A 1 91 ? 40.642 63.931 14.691 1.00 11.01 ? 91 ASN A CG 1 ATOM 506 O OD1 . ASN A 1 91 ? 41.188 64.818 15.336 1.00 10.98 ? 91 ASN A OD1 1 ATOM 507 N ND2 . ASN A 1 91 ? 40.037 62.896 15.264 1.00 10.32 ? 91 ASN A ND2 1 ATOM 508 N N . ASP A 1 92 ? 38.943 65.817 10.854 1.00 9.72 ? 92 ASP A N 1 ATOM 509 C CA . ASP A 1 92 ? 39.002 66.371 9.503 1.00 11.42 ? 92 ASP A CA 1 ATOM 510 C C . ASP A 1 92 ? 40.263 67.228 9.260 1.00 10.38 ? 92 ASP A C 1 ATOM 511 O O . ASP A 1 92 ? 40.465 68.214 9.955 1.00 10.91 ? 92 ASP A O 1 ATOM 512 C CB . ASP A 1 92 ? 37.784 67.270 9.245 1.00 9.75 ? 92 ASP A CB 1 ATOM 513 C CG . ASP A 1 92 ? 36.495 66.492 9.213 1.00 12.50 ? 92 ASP A CG 1 ATOM 514 O OD1 . ASP A 1 92 ? 36.480 65.454 8.540 1.00 13.17 ? 92 ASP A OD1 1 ATOM 515 O OD2 . ASP A 1 92 ? 35.515 66.896 9.858 1.00 12.88 ? 92 ASP A OD2 1 ATOM 516 N N . PRO A 1 93 ? 41.110 66.854 8.280 1.00 11.20 ? 93 PRO A N 1 ATOM 517 C CA . PRO A 1 93 ? 42.331 67.591 7.928 1.00 10.94 ? 93 PRO A CA 1 ATOM 518 C C . PRO A 1 93 ? 41.845 68.852 7.186 1.00 11.41 ? 93 PRO A C 1 ATOM 519 O O . PRO A 1 93 ? 42.063 69.020 5.980 1.00 10.81 ? 93 PRO A O 1 ATOM 520 C CB . PRO A 1 93 ? 43.048 66.632 6.997 1.00 11.44 ? 93 PRO A CB 1 ATOM 521 C CG . PRO A 1 93 ? 42.610 65.275 7.496 1.00 12.32 ? 93 PRO A CG 1 ATOM 522 C CD . PRO A 1 93 ? 41.131 65.516 7.669 1.00 11.76 ? 93 PRO A CD 1 ATOM 523 N N . GLY A 1 94 ? 41.137 69.695 7.941 1.00 10.94 ? 94 GLY A N 1 ATOM 524 C CA . GLY A 1 94 ? 40.551 70.918 7.428 1.00 10.04 ? 94 GLY A CA 1 ATOM 525 C C . GLY A 1 94 ? 39.082 70.672 7.130 1.00 10.75 ? 94 GLY A C 1 ATOM 526 O O . GLY A 1 94 ? 38.732 69.598 6.612 1.00 10.09 ? 94 GLY A O 1 ATOM 527 N N . TRP A 1 95 ? 38.226 71.630 7.496 1.00 9.23 ? 95 TRP A N 1 ATOM 528 C CA . TRP A 1 95 ? 36.780 71.609 7.185 1.00 10.39 ? 95 TRP A CA 1 ATOM 529 C C . TRP A 1 95 ? 36.257 73.012 7.588 1.00 12.09 ? 95 TRP A C 1 ATOM 530 O O . TRP A 1 95 ? 36.178 73.937 6.754 1.00 10.64 ? 95 TRP A O 1 ATOM 531 C CB . TRP A 1 95 ? 36.022 70.492 7.941 1.00 7.97 ? 95 TRP A CB 1 ATOM 532 C CG . TRP A 1 95 ? 34.508 70.549 7.645 1.00 9.54 ? 95 TRP A CG 1 ATOM 533 C CD1 . TRP A 1 95 ? 33.916 70.995 6.478 1.00 7.89 ? 95 TRP A CD1 1 ATOM 534 C CD2 . TRP A 1 95 ? 33.431 70.186 8.518 1.00 7.99 ? 95 TRP A CD2 1 ATOM 535 N NE1 . TRP A 1 95 ? 32.549 70.946 6.586 1.00 10.16 ? 95 TRP A NE1 1 ATOM 536 C CE2 . TRP A 1 95 ? 32.219 70.448 7.822 1.00 8.25 ? 95 TRP A CE2 1 ATOM 537 C CE3 . TRP A 1 95 ? 33.367 69.664 9.825 1.00 8.23 ? 95 TRP A CE3 1 ATOM 538 C CZ2 . TRP A 1 95 ? 30.956 70.203 8.385 1.00 9.08 ? 95 TRP A CZ2 1 ATOM 539 C CZ3 . TRP A 1 95 ? 32.097 69.418 10.396 1.00 8.35 ? 95 TRP A CZ3 1 ATOM 540 C CH2 . TRP A 1 95 ? 30.912 69.687 9.671 1.00 8.13 ? 95 TRP A CH2 1 ATOM 541 N N . ILE A 1 96 ? 35.968 73.161 8.884 1.00 12.98 ? 96 ILE A N 1 ATOM 542 C CA . ILE A 1 96 ? 35.517 74.428 9.484 1.00 14.85 ? 96 ILE A CA 1 ATOM 543 C C . ILE A 1 96 ? 36.737 75.252 9.917 1.00 14.95 ? 96 ILE A C 1 ATOM 544 O O . ILE A 1 96 ? 36.668 76.466 9.970 1.00 15.39 ? 96 ILE A O 1 ATOM 545 C CB . ILE A 1 96 ? 34.644 74.179 10.729 1.00 16.71 ? 96 ILE A CB 1 ATOM 546 C CG1 . ILE A 1 96 ? 33.427 73.366 10.314 1.00 17.75 ? 96 ILE A CG1 1 ATOM 547 C CG2 . ILE A 1 96 ? 34.186 75.516 11.348 1.00 19.66 ? 96 ILE A CG2 1 ATOM 548 C CD1 . ILE A 1 96 ? 32.857 73.846 8.991 1.00 15.97 ? 96 ILE A CD1 1 ATOM 549 N N . GLN A 1 97 ? 37.840 74.574 10.235 1.00 14.38 ? 97 GLN A N 1 ATOM 550 C CA . GLN A 1 97 ? 39.103 75.228 10.580 1.00 13.71 ? 97 GLN A CA 1 ATOM 551 C C . GLN A 1 97 ? 40.130 74.637 9.585 1.00 12.34 ? 97 GLN A C 1 ATOM 552 O O . GLN A 1 97 ? 39.852 73.642 8.909 1.00 11.59 ? 97 GLN A O 1 ATOM 553 C CB . GLN A 1 97 ? 39.495 74.877 12.014 1.00 14.67 ? 97 GLN A CB 1 ATOM 554 C CG . GLN A 1 97 ? 38.513 75.381 13.104 1.00 17.86 ? 97 GLN A CG 1 ATOM 555 C CD . GLN A 1 97 ? 39.036 75.114 14.539 1.00 20.04 ? 97 GLN A CD 1 ATOM 556 O OE1 . GLN A 1 97 ? 40.151 75.515 14.888 1.00 21.78 ? 97 GLN A OE1 1 ATOM 557 N NE2 . GLN A 1 97 ? 38.234 74.422 15.365 1.00 20.13 ? 97 GLN A NE2 1 ATOM 558 N N . THR A 1 98 ? 41.305 75.235 9.466 1.00 10.66 ? 98 THR A N 1 ATOM 559 C CA . THR A 1 98 ? 42.314 74.661 8.588 1.00 10.47 ? 98 THR A CA 1 ATOM 560 C C . THR A 1 98 ? 42.965 73.461 9.297 1.00 10.91 ? 98 THR A C 1 ATOM 561 O O . THR A 1 98 ? 42.783 73.235 10.512 1.00 10.78 ? 98 THR A O 1 ATOM 562 C CB . THR A 1 98 ? 43.449 75.628 8.324 1.00 11.07 ? 98 THR A CB 1 ATOM 563 O OG1 . THR A 1 98 ? 44.096 75.915 9.577 1.00 12.68 ? 98 THR A OG1 1 ATOM 564 C CG2 . THR A 1 98 ? 42.927 76.962 7.730 1.00 9.88 ? 98 THR A CG2 1 ATOM 565 N N . PHE A 1 99 ? 43.704 72.674 8.531 1.00 9.25 ? 99 PHE A N 1 ATOM 566 C CA . PHE A 1 99 ? 44.452 71.551 9.099 1.00 9.89 ? 99 PHE A CA 1 ATOM 567 C C . PHE A 1 99 ? 45.220 71.986 10.367 1.00 10.26 ? 99 PHE A C 1 ATOM 568 O O . PHE A 1 99 ? 45.083 71.382 11.425 1.00 10.04 ? 99 PHE A O 1 ATOM 569 C CB . PHE A 1 99 ? 45.477 71.037 8.081 1.00 8.24 ? 99 PHE A CB 1 ATOM 570 C CG . PHE A 1 99 ? 46.348 69.897 8.612 1.00 10.69 ? 99 PHE A CG 1 ATOM 571 C CD1 . PHE A 1 99 ? 45.948 68.561 8.473 1.00 8.53 ? 99 PHE A CD1 1 ATOM 572 C CD2 . PHE A 1 99 ? 47.547 70.168 9.257 1.00 9.33 ? 99 PHE A CD2 1 ATOM 573 C CE1 . PHE A 1 99 ? 46.733 67.521 8.972 1.00 11.04 ? 99 PHE A CE1 1 ATOM 574 C CE2 . PHE A 1 99 ? 48.337 69.136 9.758 1.00 12.54 ? 99 PHE A CE2 1 ATOM 575 C CZ . PHE A 1 99 ? 47.922 67.797 9.611 1.00 10.18 ? 99 PHE A CZ 1 ATOM 576 N N . GLU A 1 100 ? 46.037 73.034 10.257 1.00 10.75 ? 100 GLU A N 1 ATOM 577 C CA . GLU A 1 100 ? 46.835 73.491 11.396 1.00 11.57 ? 100 GLU A CA 1 ATOM 578 C C . GLU A 1 100 ? 46.007 74.028 12.553 1.00 10.86 ? 100 GLU A C 1 ATOM 579 O O . GLU A 1 100 ? 46.360 73.820 13.707 1.00 10.65 ? 100 GLU A O 1 ATOM 580 C CB . GLU A 1 100 ? 47.847 74.556 10.931 1.00 12.21 ? 100 GLU A CB 1 ATOM 581 C CG . GLU A 1 100 ? 48.868 74.965 11.962 1.00 14.02 ? 100 GLU A CG 1 ATOM 582 C CD . GLU A 1 100 ? 49.732 73.808 12.430 1.00 16.09 ? 100 GLU A CD 1 ATOM 583 O OE1 . GLU A 1 100 ? 49.843 72.790 11.686 1.00 13.49 ? 100 GLU A OE1 1 ATOM 584 O OE2 . GLU A 1 100 ? 50.309 73.927 13.542 1.00 16.34 ? 100 GLU A OE2 1 ATOM 585 N N . GLU A 1 101 ? 44.908 74.718 12.258 1.00 11.54 ? 101 GLU A N 1 ATOM 586 C CA . GLU A 1 101 ? 44.054 75.230 13.338 1.00 13.07 ? 101 GLU A CA 1 ATOM 587 C C . GLU A 1 101 ? 43.462 74.033 14.123 1.00 12.64 ? 101 GLU A C 1 ATOM 588 O O . GLU A 1 101 ? 43.492 73.995 15.359 1.00 10.67 ? 101 GLU A O 1 ATOM 589 C CB . GLU A 1 101 ? 42.924 76.102 12.758 1.00 16.20 ? 101 GLU A CB 1 ATOM 590 C CG . GLU A 1 101 ? 43.479 77.355 12.046 1.00 18.42 ? 101 GLU A CG 1 ATOM 591 C CD . GLU A 1 101 ? 42.399 78.208 11.379 1.00 20.90 ? 101 GLU A CD 1 ATOM 592 O OE1 . GLU A 1 101 ? 41.420 77.661 10.823 1.00 17.36 ? 101 GLU A OE1 1 ATOM 593 O OE2 . GLU A 1 101 ? 42.552 79.443 11.404 1.00 21.22 ? 101 GLU A OE2 1 ATOM 594 N N . TYR A 1 102 ? 42.925 73.060 13.392 1.00 11.58 ? 102 TYR A N 1 ATOM 595 C CA . TYR A 1 102 ? 42.385 71.875 14.045 1.00 12.33 ? 102 TYR A CA 1 ATOM 596 C C . TYR A 1 102 ? 43.486 71.153 14.835 1.00 12.53 ? 102 TYR A C 1 ATOM 597 O O . TYR A 1 102 ? 43.266 70.698 15.962 1.00 12.18 ? 102 TYR A O 1 ATOM 598 C CB . TYR A 1 102 ? 41.832 70.897 13.027 1.00 12.22 ? 102 TYR A CB 1 ATOM 599 C CG . TYR A 1 102 ? 40.420 71.157 12.631 1.00 12.56 ? 102 TYR A CG 1 ATOM 600 C CD1 . TYR A 1 102 ? 39.430 71.402 13.600 1.00 13.11 ? 102 TYR A CD1 1 ATOM 601 C CD2 . TYR A 1 102 ? 40.032 71.018 11.296 1.00 11.86 ? 102 TYR A CD2 1 ATOM 602 C CE1 . TYR A 1 102 ? 38.067 71.478 13.231 1.00 13.21 ? 102 TYR A CE1 1 ATOM 603 C CE2 . TYR A 1 102 ? 38.714 71.100 10.921 1.00 12.46 ? 102 TYR A CE2 1 ATOM 604 C CZ . TYR A 1 102 ? 37.725 71.323 11.877 1.00 12.25 ? 102 TYR A CZ 1 ATOM 605 O OH . TYR A 1 102 ? 36.426 71.385 11.440 1.00 10.88 ? 102 TYR A OH 1 ATOM 606 N N . TYR A 1 103 ? 44.669 71.031 14.235 1.00 11.84 ? 103 TYR A N 1 ATOM 607 C CA . TYR A 1 103 ? 45.724 70.337 14.955 1.00 13.16 ? 103 TYR A CA 1 ATOM 608 C C . TYR A 1 103 ? 46.034 71.029 16.289 1.00 13.72 ? 103 TYR A C 1 ATOM 609 O O . TYR A 1 103 ? 46.179 70.359 17.320 1.00 12.37 ? 103 TYR A O 1 ATOM 610 C CB . TYR A 1 103 ? 46.995 70.261 14.136 1.00 11.76 ? 103 TYR A CB 1 ATOM 611 C CG . TYR A 1 103 ? 48.119 69.612 14.888 1.00 12.82 ? 103 TYR A CG 1 ATOM 612 C CD1 . TYR A 1 103 ? 48.091 68.236 15.172 1.00 11.66 ? 103 TYR A CD1 1 ATOM 613 C CD2 . TYR A 1 103 ? 49.215 70.377 15.356 1.00 13.10 ? 103 TYR A CD2 1 ATOM 614 C CE1 . TYR A 1 103 ? 49.118 67.646 15.901 1.00 13.68 ? 103 TYR A CE1 1 ATOM 615 C CE2 . TYR A 1 103 ? 50.252 69.793 16.097 1.00 11.86 ? 103 TYR A CE2 1 ATOM 616 C CZ . TYR A 1 103 ? 50.194 68.429 16.367 1.00 13.28 ? 103 TYR A CZ 1 ATOM 617 O OH . TYR A 1 103 ? 51.186 67.831 17.112 1.00 14.88 ? 103 TYR A OH 1 ATOM 618 N N . GLN A 1 104 ? 46.139 72.357 16.272 1.00 14.24 ? 104 GLN A N 1 ATOM 619 C CA . GLN A 1 104 ? 46.460 73.090 17.498 1.00 15.34 ? 104 GLN A CA 1 ATOM 620 C C . GLN A 1 104 ? 45.310 73.111 18.461 1.00 16.41 ? 104 GLN A C 1 ATOM 621 O O . GLN A 1 104 ? 45.509 73.010 19.672 1.00 17.58 ? 104 GLN A O 1 ATOM 622 C CB . GLN A 1 104 ? 46.845 74.550 17.207 1.00 16.08 ? 104 GLN A CB 1 ATOM 623 C CG . GLN A 1 104 ? 48.168 74.738 16.471 1.00 14.82 ? 104 GLN A CG 1 ATOM 624 C CD . GLN A 1 104 ? 49.344 74.147 17.245 1.00 18.36 ? 104 GLN A CD 1 ATOM 625 O OE1 . GLN A 1 104 ? 49.376 74.193 18.487 1.00 17.47 ? 104 GLN A OE1 1 ATOM 626 N NE2 . GLN A 1 104 ? 50.328 73.603 16.518 1.00 16.54 ? 104 GLN A NE2 1 ATOM 627 N N . HIS A 1 105 ? 44.094 73.240 17.949 1.00 16.79 ? 105 HIS A N 1 ATOM 628 C CA . HIS A 1 105 ? 42.939 73.356 18.838 1.00 17.57 ? 105 HIS A CA 1 ATOM 629 C C . HIS A 1 105 ? 42.318 72.075 19.372 1.00 17.47 ? 105 HIS A C 1 ATOM 630 O O . HIS A 1 105 ? 41.755 72.090 20.459 1.00 16.89 ? 105 HIS A O 1 ATOM 631 C CB . HIS A 1 105 ? 41.843 74.177 18.151 1.00 19.41 ? 105 HIS A CB 1 ATOM 632 C CG . HIS A 1 105 ? 42.290 75.547 17.740 1.00 22.01 ? 105 HIS A CG 1 ATOM 633 N ND1 . HIS A 1 105 ? 41.615 76.304 16.802 1.00 23.37 ? 105 HIS A ND1 1 ATOM 634 C CD2 . HIS A 1 105 ? 43.350 76.293 18.136 1.00 22.97 ? 105 HIS A CD2 1 ATOM 635 C CE1 . HIS A 1 105 ? 42.243 77.456 16.641 1.00 23.71 ? 105 HIS A CE1 1 ATOM 636 N NE2 . HIS A 1 105 ? 43.298 77.474 17.437 1.00 23.54 ? 105 HIS A NE2 1 ATOM 637 N N . ASP A 1 106 ? 42.420 70.984 18.611 1.00 15.89 ? 106 ASP A N 1 ATOM 638 C CA . ASP A 1 106 ? 41.801 69.723 19.010 1.00 15.68 ? 106 ASP A CA 1 ATOM 639 C C . ASP A 1 106 ? 42.628 68.464 18.879 1.00 14.08 ? 106 ASP A C 1 ATOM 640 O O . ASP A 1 106 ? 42.858 67.734 19.858 1.00 14.14 ? 106 ASP A O 1 ATOM 641 C CB . ASP A 1 106 ? 40.521 69.509 18.182 1.00 17.53 ? 106 ASP A CB 1 ATOM 642 C CG . ASP A 1 106 ? 39.499 70.639 18.364 1.00 19.10 ? 106 ASP A CG 1 ATOM 643 O OD1 . ASP A 1 106 ? 38.766 70.630 19.360 1.00 21.25 ? 106 ASP A OD1 1 ATOM 644 O OD2 . ASP A 1 106 ? 39.449 71.544 17.519 1.00 20.41 ? 106 ASP A OD2 1 ATOM 645 N N . THR A 1 107 ? 43.063 68.195 17.651 1.00 12.93 ? 107 THR A N 1 ATOM 646 C CA . THR A 1 107 ? 43.768 66.955 17.369 1.00 11.45 ? 107 THR A CA 1 ATOM 647 C C . THR A 1 107 ? 45.019 66.661 18.181 1.00 10.73 ? 107 THR A C 1 ATOM 648 O O . THR A 1 107 ? 45.210 65.528 18.628 1.00 9.92 ? 107 THR A O 1 ATOM 649 C CB . THR A 1 107 ? 44.098 66.856 15.882 1.00 11.51 ? 107 THR A CB 1 ATOM 650 O OG1 . THR A 1 107 ? 42.905 67.080 15.125 1.00 11.45 ? 107 THR A OG1 1 ATOM 651 C CG2 . THR A 1 107 ? 44.654 65.478 15.552 1.00 10.74 ? 107 THR A CG2 1 ATOM 652 N N . LYS A 1 108 ? 45.895 67.636 18.377 1.00 10.70 ? 108 LYS A N 1 ATOM 653 C CA . LYS A 1 108 ? 47.073 67.300 19.193 1.00 11.42 ? 108 LYS A CA 1 ATOM 654 C C . LYS A 1 108 ? 46.640 66.923 20.614 1.00 10.95 ? 108 LYS A C 1 ATOM 655 O O . LYS A 1 108 ? 47.286 66.096 21.250 1.00 11.19 ? 108 LYS A O 1 ATOM 656 C CB . LYS A 1 108 ? 48.107 68.448 19.242 1.00 12.48 ? 108 LYS A CB 1 ATOM 657 C CG . LYS A 1 108 ? 47.714 69.700 20.029 1.00 15.12 ? 108 LYS A CG 1 ATOM 658 C CD . LYS A 1 108 ? 48.878 70.720 19.937 1.00 15.38 ? 108 LYS A CD 1 ATOM 659 C CE . LYS A 1 108 ? 48.664 71.928 20.832 1.00 16.89 ? 108 LYS A CE 1 ATOM 660 N NZ . LYS A 1 108 ? 49.860 72.801 20.800 1.00 16.78 ? 108 LYS A NZ 1 ATOM 661 N N . HIS A 1 109 ? 45.534 67.498 21.096 1.00 10.71 ? 109 HIS A N 1 ATOM 662 C CA . HIS A 1 109 ? 45.066 67.175 22.444 1.00 12.35 ? 109 HIS A CA 1 ATOM 663 C C . HIS A 1 109 ? 44.447 65.793 22.441 1.00 12.26 ? 109 HIS A C 1 ATOM 664 O O . HIS A 1 109 ? 44.625 65.024 23.386 1.00 12.45 ? 109 HIS A O 1 ATOM 665 C CB . HIS A 1 109 ? 44.066 68.222 22.937 1.00 13.15 ? 109 HIS A CB 1 ATOM 666 C CG . HIS A 1 109 ? 44.644 69.594 22.968 1.00 15.56 ? 109 HIS A CG 1 ATOM 667 N ND1 . HIS A 1 109 ? 45.713 69.929 23.781 1.00 18.09 ? 109 HIS A ND1 1 ATOM 668 C CD2 . HIS A 1 109 ? 44.418 70.671 22.181 1.00 16.18 ? 109 HIS A CD2 1 ATOM 669 C CE1 . HIS A 1 109 ? 46.120 71.153 23.486 1.00 17.26 ? 109 HIS A CE1 1 ATOM 670 N NE2 . HIS A 1 109 ? 45.353 71.622 22.515 1.00 16.81 ? 109 HIS A NE2 1 ATOM 671 N N . ILE A 1 110 ? 43.724 65.470 21.367 1.00 12.52 ? 110 ILE A N 1 ATOM 672 C CA . ILE A 1 110 ? 43.119 64.147 21.250 1.00 13.07 ? 110 ILE A CA 1 ATOM 673 C C . ILE A 1 110 ? 44.211 63.078 21.244 1.00 13.29 ? 110 ILE A C 1 ATOM 674 O O . ILE A 1 110 ? 44.136 62.059 21.953 1.00 14.13 ? 110 ILE A O 1 ATOM 675 C CB . ILE A 1 110 ? 42.292 64.028 19.933 1.00 12.06 ? 110 ILE A CB 1 ATOM 676 C CG1 . ILE A 1 110 ? 41.057 64.945 20.017 1.00 11.11 ? 110 ILE A CG1 1 ATOM 677 C CG2 . ILE A 1 110 ? 41.890 62.550 19.684 1.00 12.10 ? 110 ILE A CG2 1 ATOM 678 C CD1 . ILE A 1 110 ? 40.270 65.079 18.682 1.00 11.22 ? 110 ILE A CD1 1 ATOM 679 N N . LEU A 1 111 ? 45.240 63.293 20.436 1.00 12.75 ? 111 LEU A N 1 ATOM 680 C CA . LEU A 1 111 ? 46.298 62.296 20.370 1.00 13.23 ? 111 LEU A CA 1 ATOM 681 C C . LEU A 1 111 ? 47.145 62.226 21.649 1.00 13.37 ? 111 LEU A C 1 ATOM 682 O O . LEU A 1 111 ? 47.524 61.140 22.088 1.00 13.33 ? 111 LEU A O 1 ATOM 683 C CB . LEU A 1 111 ? 47.184 62.555 19.128 1.00 13.43 ? 111 LEU A CB 1 ATOM 684 C CG . LEU A 1 111 ? 46.421 62.253 17.819 1.00 12.66 ? 111 LEU A CG 1 ATOM 685 C CD1 . LEU A 1 111 ? 47.261 62.653 16.584 1.00 10.13 ? 111 LEU A CD1 1 ATOM 686 C CD2 . LEU A 1 111 ? 46.067 60.763 17.810 1.00 12.26 ? 111 LEU A CD2 1 ATOM 687 N N . SER A 1 112 ? 47.421 63.369 22.255 1.00 12.37 ? 112 SER A N 1 ATOM 688 C CA . SER A 1 112 ? 48.199 63.388 23.484 1.00 13.34 ? 112 SER A CA 1 ATOM 689 C C . SER A 1 112 ? 47.442 62.637 24.597 1.00 13.47 ? 112 SER A C 1 ATOM 690 O O . SER A 1 112 ? 48.024 61.811 25.327 1.00 12.89 ? 112 SER A O 1 ATOM 691 C CB . SER A 1 112 ? 48.476 64.838 23.912 1.00 14.71 ? 112 SER A CB 1 ATOM 692 O OG . SER A 1 112 ? 49.172 64.802 25.148 1.00 18.22 ? 112 SER A OG 1 ATOM 693 N N . ASN A 1 113 ? 46.148 62.918 24.726 1.00 11.29 ? 113 ASN A N 1 ATOM 694 C CA . ASN A 1 113 ? 45.354 62.219 25.729 1.00 12.76 ? 113 ASN A CA 1 ATOM 695 C C . ASN A 1 113 ? 45.110 60.742 25.401 1.00 12.26 ? 113 ASN A C 1 ATOM 696 O O . ASN A 1 113 ? 44.976 59.924 26.307 1.00 12.02 ? 113 ASN A O 1 ATOM 697 C CB . ASN A 1 113 ? 44.056 62.985 26.002 1.00 13.03 ? 113 ASN A CB 1 ATOM 698 C CG . ASN A 1 113 ? 44.344 64.259 26.798 1.00 16.09 ? 113 ASN A CG 1 ATOM 699 O OD1 . ASN A 1 113 ? 45.208 64.237 27.671 1.00 20.70 ? 113 ASN A OD1 1 ATOM 700 N ND2 . ASN A 1 113 ? 43.689 65.356 26.482 1.00 15.99 ? 113 ASN A ND2 1 ATOM 701 N N . ALA A 1 114 ? 45.060 60.400 24.115 1.00 10.57 ? 114 ALA A N 1 ATOM 702 C CA . ALA A 1 114 ? 44.907 58.996 23.725 1.00 11.52 ? 114 ALA A CA 1 ATOM 703 C C . ALA A 1 114 ? 46.175 58.259 24.196 1.00 11.27 ? 114 ALA A C 1 ATOM 704 O O . ALA A 1 114 ? 46.106 57.142 24.714 1.00 10.01 ? 114 ALA A O 1 ATOM 705 C CB . ALA A 1 114 ? 44.790 58.893 22.219 1.00 10.84 ? 114 ALA A CB 1 ATOM 706 N N . LEU A 1 115 ? 47.344 58.876 24.007 1.00 10.15 ? 115 LEU A N 1 ATOM 707 C CA . LEU A 1 115 ? 48.583 58.231 24.422 1.00 12.73 ? 115 LEU A CA 1 ATOM 708 C C . LEU A 1 115 ? 48.571 57.994 25.954 1.00 14.15 ? 115 LEU A C 1 ATOM 709 O O . LEU A 1 115 ? 48.826 56.884 26.438 1.00 14.68 ? 115 LEU A O 1 ATOM 710 C CB . LEU A 1 115 ? 49.807 59.091 23.999 1.00 12.56 ? 115 LEU A CB 1 ATOM 711 C CG . LEU A 1 115 ? 51.191 58.612 24.443 1.00 14.16 ? 115 LEU A CG 1 ATOM 712 C CD1 . LEU A 1 115 ? 51.406 57.165 23.984 1.00 13.76 ? 115 LEU A CD1 1 ATOM 713 C CD2 . LEU A 1 115 ? 52.287 59.513 23.911 1.00 14.02 ? 115 LEU A CD2 1 ATOM 714 N N . ARG A 1 116 ? 48.229 59.030 26.705 1.00 15.27 ? 116 ARG A N 1 ATOM 715 C CA . ARG A 1 116 ? 48.193 58.920 28.146 1.00 16.80 ? 116 ARG A CA 1 ATOM 716 C C . ARG A 1 116 ? 47.162 57.880 28.601 1.00 16.55 ? 116 ARG A C 1 ATOM 717 O O . ARG A 1 116 ? 47.488 56.945 29.344 1.00 17.37 ? 116 ARG A O 1 ATOM 718 C CB . ARG A 1 116 ? 47.863 60.282 28.753 1.00 18.88 ? 116 ARG A CB 1 ATOM 719 C CG . ARG A 1 116 ? 47.622 60.236 30.278 1.00 23.19 ? 116 ARG A CG 1 ATOM 720 C CD . ARG A 1 116 ? 46.913 61.528 30.723 1.00 27.71 ? 116 ARG A CD 1 ATOM 721 N NE . ARG A 1 116 ? 46.384 61.437 32.087 1.00 31.38 ? 116 ARG A NE 1 ATOM 722 C CZ . ARG A 1 116 ? 45.907 62.476 32.775 1.00 33.56 ? 116 ARG A CZ 1 ATOM 723 N NH1 . ARG A 1 116 ? 45.889 63.694 32.226 1.00 33.70 ? 116 ARG A NH1 1 ATOM 724 N NH2 . ARG A 1 116 ? 45.456 62.299 34.018 1.00 34.79 ? 116 ARG A NH2 1 ATOM 725 N N . HIS A 1 117 ? 45.922 58.034 28.147 1.00 16.21 ? 117 HIS A N 1 ATOM 726 C CA . HIS A 1 117 ? 44.893 57.105 28.544 1.00 16.78 ? 117 HIS A CA 1 ATOM 727 C C . HIS A 1 117 ? 45.063 55.659 28.170 1.00 16.33 ? 117 HIS A C 1 ATOM 728 O O . HIS A 1 117 ? 44.763 54.810 29.008 1.00 15.91 ? 117 HIS A O 1 ATOM 729 C CB . HIS A 1 117 ? 43.523 57.620 28.143 1.00 19.81 ? 117 HIS A CB 1 ATOM 730 C CG . HIS A 1 117 ? 42.987 58.612 29.129 1.00 25.00 ? 117 HIS A CG 1 ATOM 731 N ND1 . HIS A 1 117 ? 42.270 58.229 30.245 1.00 24.95 ? 117 HIS A ND1 1 ATOM 732 C CD2 . HIS A 1 117 ? 43.250 59.937 29.287 1.00 26.51 ? 117 HIS A CD2 1 ATOM 733 C CE1 . HIS A 1 117 ? 42.132 59.267 31.056 1.00 27.93 ? 117 HIS A CE1 1 ATOM 734 N NE2 . HIS A 1 117 ? 42.720 60.315 30.502 1.00 28.84 ? 117 HIS A NE2 1 ATOM 735 N N . LEU A 1 118 ? 45.552 55.356 26.963 1.00 13.80 ? 118 LEU A N 1 ATOM 736 C CA . LEU A 1 118 ? 45.759 53.964 26.588 1.00 14.35 ? 118 LEU A CA 1 ATOM 737 C C . LEU A 1 118 ? 46.963 53.417 27.356 1.00 14.67 ? 118 LEU A C 1 ATOM 738 O O . LEU A 1 118 ? 46.998 52.257 27.747 1.00 15.00 ? 118 LEU A O 1 ATOM 739 C CB . LEU A 1 118 ? 45.996 53.815 25.069 1.00 14.23 ? 118 LEU A CB 1 ATOM 740 C CG . LEU A 1 118 ? 44.800 54.300 24.201 1.00 15.62 ? 118 LEU A CG 1 ATOM 741 C CD1 . LEU A 1 118 ? 45.121 54.190 22.720 1.00 14.82 ? 118 LEU A CD1 1 ATOM 742 C CD2 . LEU A 1 118 ? 43.585 53.492 24.526 1.00 14.76 ? 118 LEU A CD2 1 ATOM 743 N N . HIS A 1 119 ? 47.974 54.246 27.551 1.00 15.08 ? 119 HIS A N 1 ATOM 744 C CA . HIS A 1 119 ? 49.146 53.794 28.287 1.00 15.58 ? 119 HIS A CA 1 ATOM 745 C C . HIS A 1 119 ? 48.719 53.346 29.698 1.00 16.12 ? 119 HIS A C 1 ATOM 746 O O . HIS A 1 119 ? 49.122 52.281 30.156 1.00 15.64 ? 119 HIS A O 1 ATOM 747 C CB . HIS A 1 119 ? 50.172 54.940 28.368 1.00 15.95 ? 119 HIS A CB 1 ATOM 748 C CG . HIS A 1 119 ? 51.341 54.647 29.247 1.00 18.59 ? 119 HIS A CG 1 ATOM 749 N ND1 . HIS A 1 119 ? 51.364 54.973 30.588 1.00 19.95 ? 119 HIS A ND1 1 ATOM 750 C CD2 . HIS A 1 119 ? 52.521 54.032 28.988 1.00 19.68 ? 119 HIS A CD2 1 ATOM 751 C CE1 . HIS A 1 119 ? 52.507 54.570 31.115 1.00 20.90 ? 119 HIS A CE1 1 ATOM 752 N NE2 . HIS A 1 119 ? 53.226 53.993 30.166 1.00 21.08 ? 119 HIS A NE2 1 ATOM 753 N N . ASP A 1 120 ? 47.876 54.148 30.350 1.00 16.01 ? 120 ASP A N 1 ATOM 754 C CA . ASP A 1 120 ? 47.417 53.864 31.721 1.00 16.70 ? 120 ASP A CA 1 ATOM 755 C C . ASP A 1 120 ? 46.273 52.867 31.907 1.00 17.04 ? 120 ASP A C 1 ATOM 756 O O . ASP A 1 120 ? 46.035 52.416 33.007 1.00 17.79 ? 120 ASP A O 1 ATOM 757 C CB . ASP A 1 120 ? 47.013 55.152 32.418 1.00 15.43 ? 120 ASP A CB 1 ATOM 758 C CG . ASP A 1 120 ? 48.186 56.063 32.670 1.00 17.50 ? 120 ASP A CG 1 ATOM 759 O OD1 . ASP A 1 120 ? 49.321 55.570 32.743 1.00 18.70 ? 120 ASP A OD1 1 ATOM 760 O OD2 . ASP A 1 120 ? 47.967 57.282 32.791 1.00 19.44 ? 120 ASP A OD2 1 ATOM 761 N N . ASN A 1 121 ? 45.552 52.545 30.841 1.00 17.49 ? 121 ASN A N 1 ATOM 762 C CA . ASN A 1 121 ? 44.430 51.609 30.917 1.00 17.15 ? 121 ASN A CA 1 ATOM 763 C C . ASN A 1 121 ? 44.646 50.562 29.828 1.00 17.96 ? 121 ASN A C 1 ATOM 764 O O . ASN A 1 121 ? 44.136 50.674 28.715 1.00 17.54 ? 121 ASN A O 1 ATOM 765 C CB . ASN A 1 121 ? 43.134 52.385 30.719 1.00 16.06 ? 121 ASN A CB 1 ATOM 766 C CG . ASN A 1 121 ? 42.921 53.431 31.814 1.00 17.40 ? 121 ASN A CG 1 ATOM 767 O OD1 . ASN A 1 121 ? 42.430 53.102 32.899 1.00 16.55 ? 121 ASN A OD1 1 ATOM 768 N ND2 . ASN A 1 121 ? 43.318 54.692 31.547 1.00 13.26 ? 121 ASN A ND2 1 ATOM 769 N N . PRO A 1 122 ? 45.394 49.505 30.157 1.00 18.20 ? 122 PRO A N 1 ATOM 770 C CA . PRO A 1 122 ? 45.714 48.422 29.223 1.00 17.38 ? 122 PRO A CA 1 ATOM 771 C C . PRO A 1 122 ? 44.592 47.847 28.377 1.00 16.81 ? 122 PRO A C 1 ATOM 772 O O . PRO A 1 122 ? 44.835 47.454 27.234 1.00 16.36 ? 122 PRO A O 1 ATOM 773 C CB . PRO A 1 122 ? 46.339 47.357 30.124 1.00 17.99 ? 122 PRO A CB 1 ATOM 774 C CG . PRO A 1 122 ? 46.919 48.171 31.243 1.00 19.37 ? 122 PRO A CG 1 ATOM 775 C CD . PRO A 1 122 ? 45.837 49.166 31.519 1.00 18.53 ? 122 PRO A CD 1 ATOM 776 N N . GLU A 1 123 ? 43.377 47.799 28.915 1.00 16.14 ? 123 GLU A N 1 ATOM 777 C CA . GLU A 1 123 ? 42.262 47.221 28.160 1.00 16.56 ? 123 GLU A CA 1 ATOM 778 C C . GLU A 1 123 ? 41.521 48.174 27.230 1.00 15.42 ? 123 GLU A C 1 ATOM 779 O O . GLU A 1 123 ? 40.706 47.723 26.420 1.00 14.11 ? 123 GLU A O 1 ATOM 780 C CB . GLU A 1 123 ? 41.231 46.585 29.101 1.00 18.77 ? 123 GLU A CB 1 ATOM 781 C CG . GLU A 1 123 ? 41.803 45.562 30.103 1.00 26.52 ? 123 GLU A CG 1 ATOM 782 C CD . GLU A 1 123 ? 42.553 44.414 29.440 1.00 30.28 ? 123 GLU A CD 1 ATOM 783 O OE1 . GLU A 1 123 ? 41.953 43.670 28.604 1.00 33.16 ? 123 GLU A OE1 1 ATOM 784 O OE2 . GLU A 1 123 ? 43.766 44.255 29.764 1.00 34.73 ? 123 GLU A OE2 1 ATOM 785 N N . MET A 1 124 ? 41.746 49.474 27.383 1.00 14.51 ? 124 MET A N 1 ATOM 786 C CA . MET A 1 124 ? 41.113 50.467 26.537 1.00 14.40 ? 124 MET A CA 1 ATOM 787 C C . MET A 1 124 ? 41.732 50.359 25.119 1.00 14.63 ? 124 MET A C 1 ATOM 788 O O . MET A 1 124 ? 42.902 50.010 24.987 1.00 15.09 ? 124 MET A O 1 ATOM 789 C CB . MET A 1 124 ? 41.346 51.867 27.118 1.00 15.56 ? 124 MET A CB 1 ATOM 790 C CG . MET A 1 124 ? 40.569 52.971 26.410 1.00 15.62 ? 124 MET A CG 1 ATOM 791 S SD . MET A 1 124 ? 38.818 52.609 26.346 1.00 16.73 ? 124 MET A SD 1 ATOM 792 C CE . MET A 1 124 ? 38.155 54.120 25.450 1.00 15.27 ? 124 MET A CE 1 ATOM 793 N N . LYS A 1 125 ? 40.930 50.632 24.087 1.00 13.69 ? 125 LYS A N 1 ATOM 794 C CA . LYS A 1 125 ? 41.332 50.567 22.668 1.00 12.74 ? 125 LYS A CA 1 ATOM 795 C C . LYS A 1 125 ? 40.928 51.866 21.937 1.00 12.44 ? 125 LYS A C 1 ATOM 796 O O . LYS A 1 125 ? 40.086 52.625 22.426 1.00 11.03 ? 125 LYS A O 1 ATOM 797 C CB . LYS A 1 125 ? 40.621 49.394 21.998 1.00 15.24 ? 125 LYS A CB 1 ATOM 798 C CG . LYS A 1 125 ? 40.855 48.051 22.691 1.00 17.90 ? 125 LYS A CG 1 ATOM 799 C CD . LYS A 1 125 ? 42.149 47.427 22.216 1.00 20.73 ? 125 LYS A CD 1 ATOM 800 C CE . LYS A 1 125 ? 42.501 46.120 22.941 1.00 22.77 ? 125 LYS A CE 1 ATOM 801 N NZ . LYS A 1 125 ? 41.553 45.016 22.679 1.00 24.79 ? 125 LYS A NZ 1 ATOM 802 N N . PHE A 1 126 ? 41.499 52.099 20.752 1.00 10.01 ? 126 PHE A N 1 ATOM 803 C CA . PHE A 1 126 ? 41.196 53.307 19.996 1.00 9.40 ? 126 PHE A CA 1 ATOM 804 C C . PHE A 1 126 ? 41.684 53.070 18.568 1.00 9.26 ? 126 PHE A C 1 ATOM 805 O O . PHE A 1 126 ? 42.724 52.445 18.376 1.00 9.14 ? 126 PHE A O 1 ATOM 806 C CB . PHE A 1 126 ? 41.969 54.488 20.623 1.00 8.34 ? 126 PHE A CB 1 ATOM 807 C CG . PHE A 1 126 ? 41.587 55.860 20.098 1.00 9.29 ? 126 PHE A CG 1 ATOM 808 C CD1 . PHE A 1 126 ? 40.249 56.286 20.096 1.00 8.18 ? 126 PHE A CD1 1 ATOM 809 C CD2 . PHE A 1 126 ? 42.586 56.769 19.729 1.00 9.47 ? 126 PHE A CD2 1 ATOM 810 C CE1 . PHE A 1 126 ? 39.916 57.612 19.749 1.00 9.59 ? 126 PHE A CE1 1 ATOM 811 C CE2 . PHE A 1 126 ? 42.266 58.098 19.374 1.00 10.54 ? 126 PHE A CE2 1 ATOM 812 C CZ . PHE A 1 126 ? 40.926 58.520 19.389 1.00 8.47 ? 126 PHE A CZ 1 ATOM 813 N N . ILE A 1 127 ? 40.934 53.536 17.567 1.00 9.75 ? 127 ILE A N 1 ATOM 814 C CA . ILE A 1 127 ? 41.391 53.385 16.179 1.00 9.48 ? 127 ILE A CA 1 ATOM 815 C C . ILE A 1 127 ? 41.663 54.778 15.602 1.00 9.70 ? 127 ILE A C 1 ATOM 816 O O . ILE A 1 127 ? 41.011 55.765 16.009 1.00 7.93 ? 127 ILE A O 1 ATOM 817 C CB . ILE A 1 127 ? 40.354 52.632 15.305 1.00 10.66 ? 127 ILE A CB 1 ATOM 818 C CG1 . ILE A 1 127 ? 39.012 53.370 15.300 1.00 10.78 ? 127 ILE A CG1 1 ATOM 819 C CG2 . ILE A 1 127 ? 40.165 51.215 15.859 1.00 11.70 ? 127 ILE A CG2 1 ATOM 820 C CD1 . ILE A 1 127 ? 37.999 52.716 14.350 1.00 9.04 ? 127 ILE A CD1 1 ATOM 821 N N . TRP A 1 128 ? 42.629 54.866 14.681 1.00 8.62 ? 128 TRP A N 1 ATOM 822 C CA . TRP A 1 128 ? 42.991 56.156 14.091 1.00 9.59 ? 128 TRP A CA 1 ATOM 823 C C . TRP A 1 128 ? 43.116 56.016 12.570 1.00 9.18 ? 128 TRP A C 1 ATOM 824 O O . TRP A 1 128 ? 43.778 55.105 12.082 1.00 6.50 ? 128 TRP A O 1 ATOM 825 C CB . TRP A 1 128 ? 44.318 56.674 14.664 1.00 8.81 ? 128 TRP A CB 1 ATOM 826 C CG . TRP A 1 128 ? 44.556 58.149 14.303 1.00 10.01 ? 128 TRP A CG 1 ATOM 827 C CD1 . TRP A 1 128 ? 45.309 58.658 13.267 1.00 10.56 ? 128 TRP A CD1 1 ATOM 828 C CD2 . TRP A 1 128 ? 43.937 59.267 14.936 1.00 9.56 ? 128 TRP A CD2 1 ATOM 829 N NE1 . TRP A 1 128 ? 45.186 60.040 13.224 1.00 9.27 ? 128 TRP A NE1 1 ATOM 830 C CE2 . TRP A 1 128 ? 44.349 60.434 14.237 1.00 10.03 ? 128 TRP A CE2 1 ATOM 831 C CE3 . TRP A 1 128 ? 43.064 59.398 16.045 1.00 9.40 ? 128 TRP A CE3 1 ATOM 832 C CZ2 . TRP A 1 128 ? 43.917 61.722 14.608 1.00 9.48 ? 128 TRP A CZ2 1 ATOM 833 C CZ3 . TRP A 1 128 ? 42.638 60.674 16.410 1.00 9.35 ? 128 TRP A CZ3 1 ATOM 834 C CH2 . TRP A 1 128 ? 43.067 61.822 15.687 1.00 9.79 ? 128 TRP A CH2 1 ATOM 835 N N . ALA A 1 129 ? 42.499 56.940 11.839 1.00 8.83 ? 129 ALA A N 1 ATOM 836 C CA . ALA A 1 129 ? 42.504 56.887 10.368 1.00 8.95 ? 129 ALA A CA 1 ATOM 837 C C . ALA A 1 129 ? 43.436 57.839 9.609 1.00 10.07 ? 129 ALA A C 1 ATOM 838 O O . ALA A 1 129 ? 44.058 57.447 8.639 1.00 10.13 ? 129 ALA A O 1 ATOM 839 C CB . ALA A 1 129 ? 41.050 57.092 9.835 1.00 8.00 ? 129 ALA A CB 1 ATOM 840 N N . GLU A 1 130 ? 43.531 59.090 10.055 1.00 11.58 ? 130 GLU A N 1 ATOM 841 C CA . GLU A 1 130 ? 44.293 60.112 9.335 1.00 11.79 ? 130 GLU A CA 1 ATOM 842 C C . GLU A 1 130 ? 45.771 60.279 9.669 1.00 12.31 ? 130 GLU A C 1 ATOM 843 O O . GLU A 1 130 ? 46.131 60.970 10.648 1.00 10.18 ? 130 GLU A O 1 ATOM 844 C CB . GLU A 1 130 ? 43.589 61.463 9.505 1.00 12.89 ? 130 GLU A CB 1 ATOM 845 C CG . GLU A 1 130 ? 42.095 61.480 9.142 1.00 13.48 ? 130 GLU A CG 1 ATOM 846 C CD . GLU A 1 130 ? 41.208 60.903 10.232 1.00 15.70 ? 130 GLU A CD 1 ATOM 847 O OE1 . GLU A 1 130 ? 41.667 60.829 11.404 1.00 17.68 ? 130 GLU A OE1 1 ATOM 848 O OE2 . GLU A 1 130 ? 40.044 60.525 9.937 1.00 15.21 ? 130 GLU A OE2 1 ATOM 849 N N . ILE A 1 131 ? 46.619 59.704 8.817 1.00 10.60 ? 131 ILE A N 1 ATOM 850 C CA . ILE A 1 131 ? 48.038 59.781 9.059 1.00 10.66 ? 131 ILE A CA 1 ATOM 851 C C . ILE A 1 131 ? 48.609 61.189 8.927 1.00 10.35 ? 131 ILE A C 1 ATOM 852 O O . ILE A 1 131 ? 49.621 61.500 9.573 1.00 12.19 ? 131 ILE A O 1 ATOM 853 C CB . ILE A 1 131 ? 48.782 58.763 8.180 1.00 10.35 ? 131 ILE A CB 1 ATOM 854 C CG1 . ILE A 1 131 ? 48.184 57.360 8.433 1.00 10.90 ? 131 ILE A CG1 1 ATOM 855 C CG2 . ILE A 1 131 ? 50.274 58.766 8.494 1.00 11.48 ? 131 ILE A CG2 1 ATOM 856 C CD1 . ILE A 1 131 ? 47.971 56.976 9.941 1.00 9.91 ? 131 ILE A CD1 1 ATOM 857 N N . SER A 1 132 ? 47.958 62.073 8.170 1.00 8.02 ? 132 SER A N 1 ATOM 858 C CA . SER A 1 132 ? 48.486 63.448 8.058 1.00 7.20 ? 132 SER A CA 1 ATOM 859 C C . SER A 1 132 ? 48.613 64.061 9.458 1.00 8.29 ? 132 SER A C 1 ATOM 860 O O . SER A 1 132 ? 49.631 64.682 9.802 1.00 8.22 ? 132 SER A O 1 ATOM 861 C CB . SER A 1 132 ? 47.591 64.335 7.163 1.00 5.98 ? 132 SER A CB 1 ATOM 862 O OG . SER A 1 132 ? 46.226 64.328 7.549 1.00 5.91 ? 132 SER A OG 1 ATOM 863 N N . TYR A 1 133 ? 47.583 63.865 10.271 1.00 9.58 ? 133 TYR A N 1 ATOM 864 C CA . TYR A 1 133 ? 47.561 64.375 11.648 1.00 9.64 ? 133 TYR A CA 1 ATOM 865 C C . TYR A 1 133 ? 48.502 63.566 12.545 1.00 10.64 ? 133 TYR A C 1 ATOM 866 O O . TYR A 1 133 ? 49.227 64.137 13.379 1.00 11.75 ? 133 TYR A O 1 ATOM 867 C CB . TYR A 1 133 ? 46.153 64.269 12.223 1.00 8.26 ? 133 TYR A CB 1 ATOM 868 C CG . TYR A 1 133 ? 45.257 65.464 11.957 1.00 7.51 ? 133 TYR A CG 1 ATOM 869 C CD1 . TYR A 1 133 ? 43.976 65.279 11.453 1.00 7.01 ? 133 TYR A CD1 1 ATOM 870 C CD2 . TYR A 1 133 ? 45.696 66.761 12.210 1.00 7.11 ? 133 TYR A CD2 1 ATOM 871 C CE1 . TYR A 1 133 ? 43.149 66.343 11.195 1.00 7.83 ? 133 TYR A CE1 1 ATOM 872 C CE2 . TYR A 1 133 ? 44.865 67.869 11.966 1.00 10.39 ? 133 TYR A CE2 1 ATOM 873 C CZ . TYR A 1 133 ? 43.592 67.637 11.459 1.00 9.63 ? 133 TYR A CZ 1 ATOM 874 O OH . TYR A 1 133 ? 42.743 68.685 11.277 1.00 11.35 ? 133 TYR A OH 1 ATOM 875 N N . PHE A 1 134 ? 48.487 62.244 12.391 1.00 10.37 ? 134 PHE A N 1 ATOM 876 C CA . PHE A 1 134 ? 49.344 61.430 13.256 1.00 10.52 ? 134 PHE A CA 1 ATOM 877 C C . PHE A 1 134 ? 50.828 61.710 13.049 1.00 11.02 ? 134 PHE A C 1 ATOM 878 O O . PHE A 1 134 ? 51.598 61.792 14.028 1.00 10.68 ? 134 PHE A O 1 ATOM 879 C CB . PHE A 1 134 ? 49.083 59.945 13.067 1.00 10.07 ? 134 PHE A CB 1 ATOM 880 C CG . PHE A 1 134 ? 49.626 59.112 14.184 1.00 12.17 ? 134 PHE A CG 1 ATOM 881 C CD1 . PHE A 1 134 ? 48.888 58.927 15.356 1.00 12.02 ? 134 PHE A CD1 1 ATOM 882 C CD2 . PHE A 1 134 ? 50.888 58.574 14.109 1.00 9.58 ? 134 PHE A CD2 1 ATOM 883 C CE1 . PHE A 1 134 ? 49.423 58.211 16.439 1.00 13.99 ? 134 PHE A CE1 1 ATOM 884 C CE2 . PHE A 1 134 ? 51.425 57.864 15.176 1.00 12.04 ? 134 PHE A CE2 1 ATOM 885 C CZ . PHE A 1 134 ? 50.680 57.685 16.353 1.00 11.74 ? 134 PHE A CZ 1 ATOM 886 N N . ALA A 1 135 ? 51.232 61.838 11.785 1.00 10.32 ? 135 ALA A N 1 ATOM 887 C CA . ALA A 1 135 ? 52.624 62.114 11.462 1.00 12.70 ? 135 ALA A CA 1 ATOM 888 C C . ALA A 1 135 ? 53.041 63.480 12.060 1.00 14.81 ? 135 ALA A C 1 ATOM 889 O O . ALA A 1 135 ? 54.152 63.622 12.594 1.00 16.08 ? 135 ALA A O 1 ATOM 890 C CB . ALA A 1 135 ? 52.805 62.118 9.957 1.00 11.46 ? 135 ALA A CB 1 ATOM 891 N N . ARG A 1 136 ? 52.154 64.472 11.963 1.00 14.51 ? 136 ARG A N 1 ATOM 892 C CA . ARG A 1 136 ? 52.403 65.806 12.488 1.00 15.53 ? 136 ARG A CA 1 ATOM 893 C C . ARG A 1 136 ? 52.631 65.724 14.013 1.00 16.57 ? 136 ARG A C 1 ATOM 894 O O . ARG A 1 136 ? 53.568 66.313 14.558 1.00 16.28 ? 136 ARG A O 1 ATOM 895 C CB . ARG A 1 136 ? 51.203 66.697 12.189 1.00 16.08 ? 136 ARG A CB 1 ATOM 896 C CG . ARG A 1 136 ? 51.209 68.083 12.874 1.00 17.84 ? 136 ARG A CG 1 ATOM 897 C CD . ARG A 1 136 ? 51.935 69.169 12.026 1.00 20.31 ? 136 ARG A CD 1 ATOM 898 N NE . ARG A 1 136 ? 51.870 70.503 12.648 1.00 17.41 ? 136 ARG A NE 1 ATOM 899 C CZ . ARG A 1 136 ? 52.607 70.816 13.709 1.00 19.91 ? 136 ARG A CZ 1 ATOM 900 N NH1 . ARG A 1 136 ? 53.444 69.892 14.194 1.00 16.16 ? 136 ARG A NH1 1 ATOM 901 N NH2 . ARG A 1 136 ? 52.472 72.001 14.317 1.00 17.19 ? 136 ARG A NH2 1 ATOM 902 N N . PHE A 1 137 ? 51.770 64.966 14.683 1.00 15.26 ? 137 PHE A N 1 ATOM 903 C CA . PHE A 1 137 ? 51.841 64.769 16.121 1.00 14.44 ? 137 PHE A CA 1 ATOM 904 C C . PHE A 1 137 ? 53.106 64.023 16.556 1.00 15.33 ? 137 PHE A C 1 ATOM 905 O O . PHE A 1 137 ? 53.875 64.494 17.393 1.00 14.56 ? 137 PHE A O 1 ATOM 906 C CB . PHE A 1 137 ? 50.632 63.974 16.579 1.00 12.75 ? 137 PHE A CB 1 ATOM 907 C CG . PHE A 1 137 ? 50.598 63.742 18.053 1.00 12.45 ? 137 PHE A CG 1 ATOM 908 C CD1 . PHE A 1 137 ? 50.274 64.787 18.926 1.00 11.08 ? 137 PHE A CD1 1 ATOM 909 C CD2 . PHE A 1 137 ? 50.894 62.484 18.574 1.00 12.05 ? 137 PHE A CD2 1 ATOM 910 C CE1 . PHE A 1 137 ? 50.240 64.583 20.283 1.00 10.81 ? 137 PHE A CE1 1 ATOM 911 C CE2 . PHE A 1 137 ? 50.861 62.260 19.952 1.00 12.73 ? 137 PHE A CE2 1 ATOM 912 C CZ . PHE A 1 137 ? 50.526 63.323 20.814 1.00 11.33 ? 137 PHE A CZ 1 ATOM 913 N N . TYR A 1 138 ? 53.309 62.849 15.976 1.00 15.04 ? 138 TYR A N 1 ATOM 914 C CA . TYR A 1 138 ? 54.456 62.008 16.303 1.00 15.79 ? 138 TYR A CA 1 ATOM 915 C C . TYR A 1 138 ? 55.803 62.722 16.172 1.00 16.71 ? 138 TYR A C 1 ATOM 916 O O . TYR A 1 138 ? 56.674 62.570 17.029 1.00 14.94 ? 138 TYR A O 1 ATOM 917 C CB . TYR A 1 138 ? 54.476 60.761 15.409 1.00 14.30 ? 138 TYR A CB 1 ATOM 918 C CG . TYR A 1 138 ? 55.525 59.723 15.811 1.00 16.99 ? 138 TYR A CG 1 ATOM 919 C CD1 . TYR A 1 138 ? 55.251 58.782 16.804 1.00 15.74 ? 138 TYR A CD1 1 ATOM 920 C CD2 . TYR A 1 138 ? 56.787 59.678 15.182 1.00 16.06 ? 138 TYR A CD2 1 ATOM 921 C CE1 . TYR A 1 138 ? 56.201 57.819 17.162 1.00 17.50 ? 138 TYR A CE1 1 ATOM 922 C CE2 . TYR A 1 138 ? 57.749 58.702 15.535 1.00 16.90 ? 138 TYR A CE2 1 ATOM 923 C CZ . TYR A 1 138 ? 57.445 57.786 16.520 1.00 17.14 ? 138 TYR A CZ 1 ATOM 924 O OH . TYR A 1 138 ? 58.365 56.828 16.898 1.00 19.78 ? 138 TYR A OH 1 ATOM 925 N N . HIS A 1 139 ? 55.997 63.475 15.098 1.00 17.92 ? 139 HIS A N 1 ATOM 926 C CA . HIS A 1 139 ? 57.278 64.142 14.951 1.00 21.71 ? 139 HIS A CA 1 ATOM 927 C C . HIS A 1 139 ? 57.521 65.202 15.995 1.00 21.04 ? 139 HIS A C 1 ATOM 928 O O . HIS A 1 139 ? 58.665 65.556 16.246 1.00 22.27 ? 139 HIS A O 1 ATOM 929 C CB . HIS A 1 139 ? 57.456 64.697 13.538 1.00 22.91 ? 139 HIS A CB 1 ATOM 930 C CG . HIS A 1 139 ? 57.702 63.623 12.524 1.00 27.91 ? 139 HIS A CG 1 ATOM 931 N ND1 . HIS A 1 139 ? 58.795 62.776 12.592 1.00 29.43 ? 139 HIS A ND1 1 ATOM 932 C CD2 . HIS A 1 139 ? 56.955 63.192 11.475 1.00 28.62 ? 139 HIS A CD2 1 ATOM 933 C CE1 . HIS A 1 139 ? 58.703 61.871 11.631 1.00 31.29 ? 139 HIS A CE1 1 ATOM 934 N NE2 . HIS A 1 139 ? 57.598 62.103 10.938 1.00 29.79 ? 139 HIS A NE2 1 ATOM 935 N N . ASP A 1 140 ? 56.453 65.706 16.597 1.00 19.62 ? 140 ASP A N 1 ATOM 936 C CA . ASP A 1 140 ? 56.583 66.702 17.668 1.00 18.44 ? 140 ASP A CA 1 ATOM 937 C C . ASP A 1 140 ? 56.801 66.067 19.060 1.00 16.76 ? 140 ASP A C 1 ATOM 938 O O . ASP A 1 140 ? 57.139 66.760 20.019 1.00 16.00 ? 140 ASP A O 1 ATOM 939 C CB . ASP A 1 140 ? 55.347 67.580 17.721 1.00 18.26 ? 140 ASP A CB 1 ATOM 940 C CG . ASP A 1 140 ? 55.415 68.744 16.722 1.00 20.95 ? 140 ASP A CG 1 ATOM 941 O OD1 . ASP A 1 140 ? 56.347 68.742 15.895 1.00 22.68 ? 140 ASP A OD1 1 ATOM 942 O OD2 . ASP A 1 140 ? 54.540 69.642 16.773 1.00 20.35 ? 140 ASP A OD2 1 ATOM 943 N N . LEU A 1 141 ? 56.614 64.761 19.172 1.00 15.69 ? 141 LEU A N 1 ATOM 944 C CA . LEU A 1 141 ? 56.772 64.072 20.457 1.00 16.29 ? 141 LEU A CA 1 ATOM 945 C C . LEU A 1 141 ? 58.205 63.904 20.890 1.00 16.29 ? 141 LEU A C 1 ATOM 946 O O . LEU A 1 141 ? 59.085 63.720 20.062 1.00 15.72 ? 141 LEU A O 1 ATOM 947 C CB . LEU A 1 141 ? 56.165 62.661 20.414 1.00 16.82 ? 141 LEU A CB 1 ATOM 948 C CG . LEU A 1 141 ? 54.662 62.429 20.516 1.00 17.39 ? 141 LEU A CG 1 ATOM 949 C CD1 . LEU A 1 141 ? 54.402 60.897 20.502 1.00 16.09 ? 141 LEU A CD1 1 ATOM 950 C CD2 . LEU A 1 141 ? 54.118 63.098 21.797 1.00 16.26 ? 141 LEU A CD2 1 ATOM 951 N N . GLY A 1 142 ? 58.442 63.956 22.195 1.00 18.05 ? 142 GLY A N 1 ATOM 952 C CA . GLY A 1 142 ? 59.796 63.715 22.676 1.00 19.30 ? 142 GLY A CA 1 ATOM 953 C C . GLY A 1 142 ? 60.054 62.212 22.521 1.00 19.50 ? 142 GLY A C 1 ATOM 954 O O . GLY A 1 142 ? 59.114 61.423 22.399 1.00 19.50 ? 142 GLY A O 1 ATOM 955 N N . GLU A 1 143 ? 61.316 61.816 22.522 1.00 20.15 ? 143 GLU A N 1 ATOM 956 C CA . GLU A 1 143 ? 61.688 60.428 22.353 1.00 20.93 ? 143 GLU A CA 1 ATOM 957 C C . GLU A 1 143 ? 61.027 59.507 23.374 1.00 21.62 ? 143 GLU A C 1 ATOM 958 O O . GLU A 1 143 ? 60.637 58.383 23.057 1.00 20.95 ? 143 GLU A O 1 ATOM 959 C CB . GLU A 1 143 ? 63.205 60.293 22.427 1.00 23.90 ? 143 GLU A CB 1 ATOM 960 C CG . GLU A 1 143 ? 63.755 58.975 21.888 1.00 26.32 ? 143 GLU A CG 1 ATOM 961 C CD . GLU A 1 143 ? 63.460 58.772 20.388 1.00 29.73 ? 143 GLU A CD 1 ATOM 962 O OE1 . GLU A 1 143 ? 63.474 59.754 19.595 1.00 30.41 ? 143 GLU A OE1 1 ATOM 963 O OE2 . GLU A 1 143 ? 63.222 57.613 20.003 1.00 31.02 ? 143 GLU A OE2 1 ATOM 964 N N . ASN A 1 144 ? 60.859 59.969 24.598 1.00 22.10 ? 144 ASN A N 1 ATOM 965 C CA . ASN A 1 144 ? 60.232 59.098 25.580 1.00 22.80 ? 144 ASN A CA 1 ATOM 966 C C . ASN A 1 144 ? 58.774 58.755 25.175 1.00 21.67 ? 144 ASN A C 1 ATOM 967 O O . ASN A 1 144 ? 58.365 57.601 25.261 1.00 19.56 ? 144 ASN A O 1 ATOM 968 C CB . ASN A 1 144 ? 60.303 59.750 26.976 1.00 25.15 ? 144 ASN A CB 1 ATOM 969 C CG . ASN A 1 144 ? 59.460 59.010 28.020 1.00 29.36 ? 144 ASN A CG 1 ATOM 970 O OD1 . ASN A 1 144 ? 58.244 59.257 28.156 1.00 31.59 ? 144 ASN A OD1 1 ATOM 971 N ND2 . ASN A 1 144 ? 60.098 58.092 28.759 1.00 28.94 ? 144 ASN A ND2 1 ATOM 972 N N . LYS A 1 145 ? 58.011 59.753 24.719 1.00 21.10 ? 145 LYS A N 1 ATOM 973 C CA . LYS A 1 145 ? 56.620 59.529 24.318 1.00 20.03 ? 145 LYS A CA 1 ATOM 974 C C . LYS A 1 145 ? 56.522 58.758 23.001 1.00 19.23 ? 145 LYS A C 1 ATOM 975 O O . LYS A 1 145 ? 55.564 58.015 22.793 1.00 18.45 ? 145 LYS A O 1 ATOM 976 C CB . LYS A 1 145 ? 55.871 60.861 24.207 1.00 21.93 ? 145 LYS A CB 1 ATOM 977 C CG . LYS A 1 145 ? 55.680 61.608 25.560 1.00 24.50 ? 145 LYS A CG 1 ATOM 978 C CD . LYS A 1 145 ? 54.886 60.773 26.566 1.00 28.04 ? 145 LYS A CD 1 ATOM 979 C CE . LYS A 1 145 ? 54.551 61.538 27.870 1.00 29.65 ? 145 LYS A CE 1 ATOM 980 N NZ . LYS A 1 145 ? 55.755 61.944 28.667 1.00 33.13 ? 145 LYS A NZ 1 ATOM 981 N N . LYS A 1 146 ? 57.491 58.955 22.101 1.00 18.12 ? 146 LYS A N 1 ATOM 982 C CA . LYS A 1 146 ? 57.496 58.214 20.826 1.00 17.13 ? 146 LYS A CA 1 ATOM 983 C C . LYS A 1 146 ? 57.579 56.734 21.146 1.00 16.17 ? 146 LYS A C 1 ATOM 984 O O . LYS A 1 146 ? 56.946 55.920 20.493 1.00 15.86 ? 146 LYS A O 1 ATOM 985 C CB . LYS A 1 146 ? 58.697 58.577 19.940 1.00 16.26 ? 146 LYS A CB 1 ATOM 986 C CG . LYS A 1 146 ? 58.584 59.936 19.266 1.00 18.16 ? 146 LYS A CG 1 ATOM 987 C CD . LYS A 1 146 ? 59.706 60.184 18.253 1.00 20.90 ? 146 LYS A CD 1 ATOM 988 C CE . LYS A 1 146 ? 59.520 61.571 17.639 1.00 21.95 ? 146 LYS A CE 1 ATOM 989 N NZ . LYS A 1 146 ? 60.629 61.833 16.753 1.00 25.66 ? 146 LYS A NZ 1 ATOM 990 N N . LEU A 1 147 ? 58.354 56.385 22.165 1.00 15.79 ? 147 LEU A N 1 ATOM 991 C CA . LEU A 1 147 ? 58.504 54.975 22.535 1.00 15.25 ? 147 LEU A CA 1 ATOM 992 C C . LEU A 1 147 ? 57.209 54.477 23.182 1.00 15.14 ? 147 LEU A C 1 ATOM 993 O O . LEU A 1 147 ? 56.789 53.345 22.949 1.00 13.16 ? 147 LEU A O 1 ATOM 994 C CB . LEU A 1 147 ? 59.687 54.784 23.494 1.00 17.93 ? 147 LEU A CB 1 ATOM 995 C CG . LEU A 1 147 ? 61.042 55.106 22.860 1.00 18.65 ? 147 LEU A CG 1 ATOM 996 C CD1 . LEU A 1 147 ? 62.151 54.983 23.884 1.00 21.46 ? 147 LEU A CD1 1 ATOM 997 C CD2 . LEU A 1 147 ? 61.308 54.149 21.724 1.00 21.19 ? 147 LEU A CD2 1 ATOM 998 N N . GLN A 1 148 ? 56.579 55.310 24.005 1.00 13.79 ? 148 GLN A N 1 ATOM 999 C CA . GLN A 1 148 ? 55.327 54.886 24.603 1.00 15.22 ? 148 GLN A CA 1 ATOM 1000 C C . GLN A 1 148 ? 54.291 54.668 23.502 1.00 14.04 ? 148 GLN A C 1 ATOM 1001 O O . GLN A 1 148 ? 53.519 53.714 23.563 1.00 12.90 ? 148 GLN A O 1 ATOM 1002 C CB . GLN A 1 148 ? 54.778 55.930 25.560 1.00 18.09 ? 148 GLN A CB 1 ATOM 1003 C CG . GLN A 1 148 ? 55.504 56.038 26.847 1.00 22.99 ? 148 GLN A CG 1 ATOM 1004 C CD . GLN A 1 148 ? 54.760 56.913 27.842 1.00 26.86 ? 148 GLN A CD 1 ATOM 1005 O OE1 . GLN A 1 148 ? 53.707 57.498 27.526 1.00 28.68 ? 148 GLN A OE1 1 ATOM 1006 N NE2 . GLN A 1 148 ? 55.302 57.007 29.054 1.00 28.35 ? 148 GLN A NE2 1 ATOM 1007 N N . MET A 1 149 ? 54.276 55.557 22.511 1.00 11.79 ? 149 MET A N 1 ATOM 1008 C CA . MET A 1 149 ? 53.317 55.445 21.408 1.00 12.65 ? 149 MET A CA 1 ATOM 1009 C C . MET A 1 149 ? 53.573 54.183 20.603 1.00 13.18 ? 149 MET A C 1 ATOM 1010 O O . MET A 1 149 ? 52.646 53.443 20.290 1.00 13.32 ? 149 MET A O 1 ATOM 1011 C CB . MET A 1 149 ? 53.395 56.668 20.481 1.00 12.74 ? 149 MET A CB 1 ATOM 1012 C CG . MET A 1 149 ? 52.409 56.655 19.315 1.00 14.14 ? 149 MET A CG 1 ATOM 1013 S SD . MET A 1 149 ? 50.700 56.799 19.886 1.00 16.70 ? 149 MET A SD 1 ATOM 1014 C CE . MET A 1 149 ? 50.573 58.498 20.039 1.00 15.09 ? 149 MET A CE 1 ATOM 1015 N N . LYS A 1 150 ? 54.823 53.935 20.254 1.00 13.20 ? 150 LYS A N 1 ATOM 1016 C CA . LYS A 1 150 ? 55.120 52.729 19.500 1.00 15.49 ? 150 LYS A CA 1 ATOM 1017 C C . LYS A 1 150 ? 54.677 51.495 20.276 1.00 14.78 ? 150 LYS A C 1 ATOM 1018 O O . LYS A 1 150 ? 54.224 50.526 19.673 1.00 14.04 ? 150 LYS A O 1 ATOM 1019 C CB . LYS A 1 150 ? 56.620 52.581 19.184 1.00 17.66 ? 150 LYS A CB 1 ATOM 1020 C CG . LYS A 1 150 ? 57.151 53.465 18.099 1.00 21.92 ? 150 LYS A CG 1 ATOM 1021 C CD . LYS A 1 150 ? 58.592 53.078 17.812 1.00 26.55 ? 150 LYS A CD 1 ATOM 1022 C CE . LYS A 1 150 ? 59.253 54.081 16.913 1.00 30.60 ? 150 LYS A CE 1 ATOM 1023 N NZ . LYS A 1 150 ? 60.472 53.495 16.288 1.00 33.25 ? 150 LYS A NZ 1 ATOM 1024 N N . SER A 1 151 ? 54.799 51.508 21.599 1.00 14.61 ? 151 SER A N 1 ATOM 1025 C CA . SER A 1 151 ? 54.403 50.305 22.320 1.00 16.02 ? 151 SER A CA 1 ATOM 1026 C C . SER A 1 151 ? 52.883 50.096 22.407 1.00 15.32 ? 151 SER A C 1 ATOM 1027 O O . SER A 1 151 ? 52.432 48.953 22.374 1.00 13.19 ? 151 SER A O 1 ATOM 1028 C CB . SER A 1 151 ? 55.041 50.253 23.718 1.00 17.13 ? 151 SER A CB 1 ATOM 1029 O OG . SER A 1 151 ? 54.288 51.011 24.620 1.00 25.86 ? 151 SER A OG 1 ATOM 1030 N N . ILE A 1 152 ? 52.080 51.161 22.508 1.00 14.26 ? 152 ILE A N 1 ATOM 1031 C CA . ILE A 1 152 ? 50.650 50.906 22.541 1.00 15.37 ? 152 ILE A CA 1 ATOM 1032 C C . ILE A 1 152 ? 50.140 50.562 21.138 1.00 15.76 ? 152 ILE A C 1 ATOM 1033 O O . ILE A 1 152 ? 49.037 50.078 20.991 1.00 18.00 ? 152 ILE A O 1 ATOM 1034 C CB . ILE A 1 152 ? 49.809 52.068 23.132 1.00 14.53 ? 152 ILE A CB 1 ATOM 1035 C CG1 . ILE A 1 152 ? 49.979 53.337 22.319 1.00 14.51 ? 152 ILE A CG1 1 ATOM 1036 C CG2 . ILE A 1 152 ? 50.184 52.303 24.599 1.00 16.71 ? 152 ILE A CG2 1 ATOM 1037 C CD1 . ILE A 1 152 ? 48.973 54.406 22.739 1.00 13.23 ? 152 ILE A CD1 1 ATOM 1038 N N . VAL A 1 153 ? 50.931 50.820 20.101 1.00 17.00 ? 153 VAL A N 1 ATOM 1039 C CA . VAL A 1 153 ? 50.524 50.428 18.742 1.00 16.30 ? 153 VAL A CA 1 ATOM 1040 C C . VAL A 1 153 ? 50.917 48.940 18.576 1.00 17.13 ? 153 VAL A C 1 ATOM 1041 O O . VAL A 1 153 ? 50.102 48.099 18.171 1.00 16.33 ? 153 VAL A O 1 ATOM 1042 C CB . VAL A 1 153 ? 51.232 51.282 17.679 1.00 16.57 ? 153 VAL A CB 1 ATOM 1043 C CG1 . VAL A 1 153 ? 51.082 50.630 16.283 1.00 15.11 ? 153 VAL A CG1 1 ATOM 1044 C CG2 . VAL A 1 153 ? 50.631 52.712 17.697 1.00 15.37 ? 153 VAL A CG2 1 ATOM 1045 N N . LYS A 1 154 ? 52.158 48.624 18.946 1.00 18.22 ? 154 LYS A N 1 ATOM 1046 C CA . LYS A 1 154 ? 52.682 47.267 18.849 1.00 20.37 ? 154 LYS A CA 1 ATOM 1047 C C . LYS A 1 154 ? 51.835 46.264 19.638 1.00 20.11 ? 154 LYS A C 1 ATOM 1048 O O . LYS A 1 154 ? 51.616 45.153 19.175 1.00 21.45 ? 154 LYS A O 1 ATOM 1049 C CB . LYS A 1 154 ? 54.119 47.208 19.363 1.00 22.05 ? 154 LYS A CB 1 ATOM 1050 C CG . LYS A 1 154 ? 54.700 45.818 19.264 1.00 26.59 ? 154 LYS A CG 1 ATOM 1051 C CD . LYS A 1 154 ? 56.003 45.718 20.017 1.00 29.46 ? 154 LYS A CD 1 ATOM 1052 C CE . LYS A 1 154 ? 57.165 46.025 19.107 1.00 31.88 ? 154 LYS A CE 1 ATOM 1053 N NZ . LYS A 1 154 ? 57.126 45.105 17.936 1.00 33.98 ? 154 LYS A NZ 1 ATOM 1054 N N . ASN A 1 155 ? 51.370 46.656 20.818 1.00 19.80 ? 155 ASN A N 1 ATOM 1055 C CA . ASN A 1 155 ? 50.533 45.798 21.656 1.00 21.04 ? 155 ASN A CA 1 ATOM 1056 C C . ASN A 1 155 ? 49.027 45.750 21.273 1.00 20.46 ? 155 ASN A C 1 ATOM 1057 O O . ASN A 1 155 ? 48.243 45.096 21.947 1.00 20.58 ? 155 ASN A O 1 ATOM 1058 C CB . ASN A 1 155 ? 50.681 46.200 23.147 1.00 23.56 ? 155 ASN A CB 1 ATOM 1059 C CG . ASN A 1 155 ? 49.793 47.409 23.554 1.00 25.84 ? 155 ASN A CG 1 ATOM 1060 O OD1 . ASN A 1 155 ? 49.053 47.955 22.730 1.00 27.69 ? 155 ASN A OD1 1 ATOM 1061 N ND2 . ASN A 1 155 ? 49.870 47.818 24.833 1.00 23.52 ? 155 ASN A ND2 1 ATOM 1062 N N . GLY A 1 156 ? 48.609 46.456 20.221 1.00 19.64 ? 156 GLY A N 1 ATOM 1063 C CA . GLY A 1 156 ? 47.208 46.376 19.796 1.00 17.38 ? 156 GLY A CA 1 ATOM 1064 C C . GLY A 1 156 ? 46.169 47.316 20.392 1.00 16.25 ? 156 GLY A C 1 ATOM 1065 O O . GLY A 1 156 ? 44.991 47.245 20.019 1.00 14.59 ? 156 GLY A O 1 ATOM 1066 N N . GLN A 1 157 ? 46.572 48.200 21.306 1.00 14.08 ? 157 GLN A N 1 ATOM 1067 C CA . GLN A 1 157 ? 45.627 49.131 21.902 1.00 13.43 ? 157 GLN A CA 1 ATOM 1068 C C . GLN A 1 157 ? 45.245 50.274 20.944 1.00 13.75 ? 157 GLN A C 1 ATOM 1069 O O . GLN A 1 157 ? 44.091 50.644 20.831 1.00 14.86 ? 157 GLN A O 1 ATOM 1070 C CB . GLN A 1 157 ? 46.213 49.736 23.179 1.00 14.31 ? 157 GLN A CB 1 ATOM 1071 C CG . GLN A 1 157 ? 45.984 48.913 24.444 1.00 12.19 ? 157 GLN A CG 1 ATOM 1072 C CD . GLN A 1 157 ? 46.439 49.689 25.651 1.00 12.66 ? 157 GLN A CD 1 ATOM 1073 O OE1 . GLN A 1 157 ? 47.613 49.672 25.997 1.00 12.96 ? 157 GLN A OE1 1 ATOM 1074 N NE2 . GLN A 1 157 ? 45.528 50.413 26.268 1.00 11.61 ? 157 GLN A NE2 1 ATOM 1075 N N . LEU A 1 158 ? 46.221 50.836 20.252 1.00 13.49 ? 158 LEU A N 1 ATOM 1076 C CA . LEU A 1 158 ? 45.930 51.927 19.313 1.00 12.79 ? 158 LEU A CA 1 ATOM 1077 C C . LEU A 1 158 ? 46.146 51.284 17.942 1.00 12.33 ? 158 LEU A C 1 ATOM 1078 O O . LEU A 1 158 ? 47.235 50.757 17.660 1.00 8.76 ? 158 LEU A O 1 ATOM 1079 C CB . LEU A 1 158 ? 46.911 53.080 19.539 1.00 14.96 ? 158 LEU A CB 1 ATOM 1080 C CG . LEU A 1 158 ? 46.759 54.459 18.881 1.00 18.91 ? 158 LEU A CG 1 ATOM 1081 C CD1 . LEU A 1 158 ? 48.178 55.009 18.596 1.00 19.70 ? 158 LEU A CD1 1 ATOM 1082 C CD2 . LEU A 1 158 ? 45.971 54.394 17.623 1.00 20.28 ? 158 LEU A CD2 1 ATOM 1083 N N . GLU A 1 159 ? 45.104 51.308 17.108 1.00 9.59 ? 159 GLU A N 1 ATOM 1084 C CA . GLU A 1 159 ? 45.194 50.671 15.801 1.00 10.24 ? 159 GLU A CA 1 ATOM 1085 C C . GLU A 1 159 ? 44.843 51.584 14.654 1.00 10.46 ? 159 GLU A C 1 ATOM 1086 O O . GLU A 1 159 ? 43.834 52.302 14.684 1.00 10.29 ? 159 GLU A O 1 ATOM 1087 C CB . GLU A 1 159 ? 44.282 49.412 15.767 1.00 11.51 ? 159 GLU A CB 1 ATOM 1088 C CG . GLU A 1 159 ? 44.165 48.702 14.425 1.00 11.91 ? 159 GLU A CG 1 ATOM 1089 C CD . GLU A 1 159 ? 43.188 47.531 14.480 1.00 14.77 ? 159 GLU A CD 1 ATOM 1090 O OE1 . GLU A 1 159 ? 43.527 46.535 15.167 1.00 13.13 ? 159 GLU A OE1 1 ATOM 1091 O OE2 . GLU A 1 159 ? 42.091 47.620 13.855 1.00 13.42 ? 159 GLU A OE2 1 ATOM 1092 N N . PHE A 1 160 ? 45.695 51.575 13.642 1.00 9.44 ? 160 PHE A N 1 ATOM 1093 C CA . PHE A 1 160 ? 45.431 52.389 12.463 1.00 9.20 ? 160 PHE A CA 1 ATOM 1094 C C . PHE A 1 160 ? 44.528 51.666 11.494 1.00 9.33 ? 160 PHE A C 1 ATOM 1095 O O . PHE A 1 160 ? 44.741 50.496 11.175 1.00 7.58 ? 160 PHE A O 1 ATOM 1096 C CB . PHE A 1 160 ? 46.742 52.732 11.780 1.00 9.66 ? 160 PHE A CB 1 ATOM 1097 C CG . PHE A 1 160 ? 47.640 53.520 12.654 1.00 10.70 ? 160 PHE A CG 1 ATOM 1098 C CD1 . PHE A 1 160 ? 48.692 52.896 13.351 1.00 11.43 ? 160 PHE A CD1 1 ATOM 1099 C CD2 . PHE A 1 160 ? 47.406 54.869 12.851 1.00 10.67 ? 160 PHE A CD2 1 ATOM 1100 C CE1 . PHE A 1 160 ? 49.496 53.620 14.223 1.00 9.75 ? 160 PHE A CE1 1 ATOM 1101 C CE2 . PHE A 1 160 ? 48.204 55.609 13.733 1.00 11.76 ? 160 PHE A CE2 1 ATOM 1102 C CZ . PHE A 1 160 ? 49.246 54.981 14.410 1.00 11.61 ? 160 PHE A CZ 1 ATOM 1103 N N . VAL A 1 161 ? 43.518 52.383 11.034 1.00 9.19 ? 161 VAL A N 1 ATOM 1104 C CA . VAL A 1 161 ? 42.560 51.848 10.096 1.00 8.76 ? 161 VAL A CA 1 ATOM 1105 C C . VAL A 1 161 ? 42.820 52.636 8.810 1.00 10.06 ? 161 VAL A C 1 ATOM 1106 O O . VAL A 1 161 ? 42.955 53.877 8.854 1.00 11.78 ? 161 VAL A O 1 ATOM 1107 C CB . VAL A 1 161 ? 41.106 52.030 10.614 1.00 7.75 ? 161 VAL A CB 1 ATOM 1108 C CG1 . VAL A 1 161 ? 40.871 51.101 11.813 1.00 7.58 ? 161 VAL A CG1 1 ATOM 1109 C CG2 . VAL A 1 161 ? 40.844 53.487 11.038 1.00 6.16 ? 161 VAL A CG2 1 ATOM 1110 N N . THR A 1 162 ? 42.890 51.901 7.695 1.00 9.36 ? 162 THR A N 1 ATOM 1111 C CA . THR A 1 162 ? 43.198 52.420 6.358 1.00 10.15 ? 162 THR A CA 1 ATOM 1112 C C . THR A 1 162 ? 44.661 52.909 6.338 1.00 10.20 ? 162 THR A C 1 ATOM 1113 O O . THR A 1 162 ? 45.498 52.384 5.598 1.00 10.89 ? 162 THR A O 1 ATOM 1114 C CB . THR A 1 162 ? 42.285 53.614 5.887 1.00 9.22 ? 162 THR A CB 1 ATOM 1115 O OG1 . THR A 1 162 ? 40.913 53.240 5.935 1.00 10.99 ? 162 THR A OG1 1 ATOM 1116 C CG2 . THR A 1 162 ? 42.602 53.966 4.423 1.00 10.40 ? 162 THR A CG2 1 ATOM 1117 N N . GLY A 1 163 ? 44.986 53.903 7.143 1.00 9.79 ? 163 GLY A N 1 ATOM 1118 C CA . GLY A 1 163 ? 46.371 54.371 7.132 1.00 10.45 ? 163 GLY A CA 1 ATOM 1119 C C . GLY A 1 163 ? 46.733 55.308 5.983 1.00 10.98 ? 163 GLY A C 1 ATOM 1120 O O . GLY A 1 163 ? 47.906 55.432 5.634 1.00 13.09 ? 163 GLY A O 1 ATOM 1121 N N . GLY A 1 164 ? 45.742 55.962 5.384 1.00 10.52 ? 164 GLY A N 1 ATOM 1122 C CA . GLY A 1 164 ? 46.014 56.911 4.314 1.00 9.94 ? 164 GLY A CA 1 ATOM 1123 C C . GLY A 1 164 ? 46.356 58.290 4.879 1.00 10.51 ? 164 GLY A C 1 ATOM 1124 O O . GLY A 1 164 ? 46.108 58.544 6.044 1.00 9.74 ? 164 GLY A O 1 ATOM 1125 N N . TRP A 1 165 ? 46.935 59.182 4.077 1.00 9.81 ? 165 TRP A N 1 ATOM 1126 C CA . TRP A 1 165 ? 47.259 60.515 4.580 1.00 8.96 ? 165 TRP A CA 1 ATOM 1127 C C . TRP A 1 165 ? 45.932 61.131 5.069 1.00 8.52 ? 165 TRP A C 1 ATOM 1128 O O . TRP A 1 165 ? 45.901 61.890 6.038 1.00 8.41 ? 165 TRP A O 1 ATOM 1129 C CB . TRP A 1 165 ? 47.865 61.345 3.451 1.00 8.38 ? 165 TRP A CB 1 ATOM 1130 C CG . TRP A 1 165 ? 48.676 62.512 3.918 1.00 8.98 ? 165 TRP A CG 1 ATOM 1131 C CD1 . TRP A 1 165 ? 48.455 63.839 3.637 1.00 8.96 ? 165 TRP A CD1 1 ATOM 1132 C CD2 . TRP A 1 165 ? 49.871 62.468 4.735 1.00 9.11 ? 165 TRP A CD2 1 ATOM 1133 N NE1 . TRP A 1 165 ? 49.433 64.616 4.233 1.00 8.61 ? 165 TRP A NE1 1 ATOM 1134 C CE2 . TRP A 1 165 ? 50.309 63.806 4.905 1.00 8.67 ? 165 TRP A CE2 1 ATOM 1135 C CE3 . TRP A 1 165 ? 50.611 61.425 5.327 1.00 10.00 ? 165 TRP A CE3 1 ATOM 1136 C CZ2 . TRP A 1 165 ? 51.453 64.135 5.647 1.00 9.14 ? 165 TRP A CZ2 1 ATOM 1137 C CZ3 . TRP A 1 165 ? 51.772 61.756 6.075 1.00 9.19 ? 165 TRP A CZ3 1 ATOM 1138 C CH2 . TRP A 1 165 ? 52.167 63.097 6.219 1.00 9.47 ? 165 TRP A CH2 1 ATOM 1139 N N . VAL A 1 166 ? 44.838 60.770 4.405 1.00 7.10 ? 166 VAL A N 1 ATOM 1140 C CA . VAL A 1 166 ? 43.504 61.252 4.764 1.00 7.41 ? 166 VAL A CA 1 ATOM 1141 C C . VAL A 1 166 ? 42.497 60.109 4.540 1.00 7.25 ? 166 VAL A C 1 ATOM 1142 O O . VAL A 1 166 ? 42.901 58.975 4.228 1.00 6.75 ? 166 VAL A O 1 ATOM 1143 C CB . VAL A 1 166 ? 43.067 62.492 3.866 1.00 6.90 ? 166 VAL A CB 1 ATOM 1144 C CG1 . VAL A 1 166 ? 44.104 63.666 3.986 1.00 5.70 ? 166 VAL A CG1 1 ATOM 1145 C CG2 . VAL A 1 166 ? 42.943 62.061 2.387 1.00 8.41 ? 166 VAL A CG2 1 ATOM 1146 N N . MET A 1 167 ? 41.206 60.412 4.735 1.00 7.85 ? 167 MET A N 1 ATOM 1147 C CA . MET A 1 167 ? 40.070 59.502 4.433 1.00 7.23 ? 167 MET A CA 1 ATOM 1148 C C . MET A 1 167 ? 39.543 60.315 3.237 1.00 7.59 ? 167 MET A C 1 ATOM 1149 O O . MET A 1 167 ? 38.799 61.296 3.398 1.00 7.93 ? 167 MET A O 1 ATOM 1150 C CB . MET A 1 167 ? 39.044 59.509 5.563 1.00 7.98 ? 167 MET A CB 1 ATOM 1151 C CG . MET A 1 167 ? 37.769 58.731 5.252 1.00 9.00 ? 167 MET A CG 1 ATOM 1152 S SD . MET A 1 167 ? 36.572 58.948 6.618 1.00 10.52 ? 167 MET A SD 1 ATOM 1153 C CE . MET A 1 167 ? 37.570 58.077 7.995 1.00 7.24 ? 167 MET A CE 1 ATOM 1154 N N . PRO A 1 168 ? 39.894 59.901 2.013 1.00 7.11 ? 168 PRO A N 1 ATOM 1155 C CA . PRO A 1 168 ? 39.456 60.679 0.865 1.00 6.21 ? 168 PRO A CA 1 ATOM 1156 C C . PRO A 1 168 ? 38.025 60.656 0.392 1.00 6.70 ? 168 PRO A C 1 ATOM 1157 O O . PRO A 1 168 ? 37.285 59.736 0.673 1.00 5.33 ? 168 PRO A O 1 ATOM 1158 C CB . PRO A 1 168 ? 40.387 60.178 -0.236 1.00 7.21 ? 168 PRO A CB 1 ATOM 1159 C CG . PRO A 1 168 ? 40.427 58.674 0.076 1.00 6.03 ? 168 PRO A CG 1 ATOM 1160 C CD . PRO A 1 168 ? 40.593 58.676 1.593 1.00 5.96 ? 168 PRO A CD 1 ATOM 1161 N N . ASP A 1 169 ? 37.699 61.692 -0.372 1.00 5.50 ? 169 ASP A N 1 ATOM 1162 C CA . ASP A 1 169 ? 36.432 61.792 -1.077 1.00 5.89 ? 169 ASP A CA 1 ATOM 1163 C C . ASP A 1 169 ? 36.500 60.620 -2.055 1.00 6.94 ? 169 ASP A C 1 ATOM 1164 O O . ASP A 1 169 ? 37.582 60.284 -2.516 1.00 5.59 ? 169 ASP A O 1 ATOM 1165 C CB . ASP A 1 169 ? 36.421 63.078 -1.891 1.00 5.76 ? 169 ASP A CB 1 ATOM 1166 C CG . ASP A 1 169 ? 35.268 63.138 -2.840 1.00 6.05 ? 169 ASP A CG 1 ATOM 1167 O OD1 . ASP A 1 169 ? 34.168 62.631 -2.508 1.00 4.74 ? 169 ASP A OD1 1 ATOM 1168 O OD2 . ASP A 1 169 ? 35.461 63.716 -3.913 1.00 7.92 ? 169 ASP A OD2 1 ATOM 1169 N N . GLU A 1 170 ? 35.366 60.016 -2.402 1.00 7.21 ? 170 GLU A N 1 ATOM 1170 C CA . GLU A 1 170 ? 35.397 58.890 -3.337 1.00 8.85 ? 170 GLU A CA 1 ATOM 1171 C C . GLU A 1 170 ? 34.707 59.240 -4.653 1.00 8.79 ? 170 GLU A C 1 ATOM 1172 O O . GLU A 1 170 ? 34.709 58.455 -5.611 1.00 9.99 ? 170 GLU A O 1 ATOM 1173 C CB . GLU A 1 170 ? 34.757 57.647 -2.669 1.00 8.68 ? 170 GLU A CB 1 ATOM 1174 C CG . GLU A 1 170 ? 35.638 57.173 -1.480 1.00 8.62 ? 170 GLU A CG 1 ATOM 1175 C CD . GLU A 1 170 ? 35.100 55.977 -0.746 1.00 10.19 ? 170 GLU A CD 1 ATOM 1176 O OE1 . GLU A 1 170 ? 34.314 55.206 -1.348 1.00 7.64 ? 170 GLU A OE1 1 ATOM 1177 O OE2 . GLU A 1 170 ? 35.495 55.805 0.437 1.00 10.28 ? 170 GLU A OE2 1 ATOM 1178 N N . ALA A 1 171 ? 34.164 60.447 -4.723 1.00 9.55 ? 171 ALA A N 1 ATOM 1179 C CA . ALA A 1 171 ? 33.469 60.844 -5.936 1.00 9.38 ? 171 ALA A CA 1 ATOM 1180 C C . ALA A 1 171 ? 34.288 61.587 -6.980 1.00 9.74 ? 171 ALA A C 1 ATOM 1181 O O . ALA A 1 171 ? 34.316 61.238 -8.174 1.00 10.07 ? 171 ALA A O 1 ATOM 1182 C CB . ALA A 1 171 ? 32.252 61.661 -5.575 1.00 9.23 ? 171 ALA A CB 1 ATOM 1183 N N . ASN A 1 172 ? 34.953 62.629 -6.530 1.00 10.08 ? 172 ASN A N 1 ATOM 1184 C CA . ASN A 1 172 ? 35.718 63.481 -7.416 1.00 8.17 ? 172 ASN A CA 1 ATOM 1185 C C . ASN A 1 172 ? 37.171 63.053 -7.583 1.00 8.32 ? 172 ASN A C 1 ATOM 1186 O O . ASN A 1 172 ? 37.833 63.415 -8.554 1.00 8.44 ? 172 ASN A O 1 ATOM 1187 C CB . ASN A 1 172 ? 35.681 64.881 -6.824 1.00 7.97 ? 172 ASN A CB 1 ATOM 1188 C CG . ASN A 1 172 ? 34.256 65.430 -6.675 1.00 8.20 ? 172 ASN A CG 1 ATOM 1189 O OD1 . ASN A 1 172 ? 33.555 65.680 -7.679 1.00 8.70 ? 172 ASN A OD1 1 ATOM 1190 N ND2 . ASN A 1 172 ? 33.827 65.643 -5.427 1.00 7.18 ? 172 ASN A ND2 1 ATOM 1191 N N . SER A 1 173 ? 37.679 62.308 -6.610 1.00 8.08 ? 173 SER A N 1 ATOM 1192 C CA . SER A 1 173 ? 39.077 61.931 -6.619 1.00 7.77 ? 173 SER A CA 1 ATOM 1193 C C . SER A 1 173 ? 39.489 61.017 -7.737 1.00 8.14 ? 173 SER A C 1 ATOM 1194 O O . SER A 1 173 ? 38.732 60.107 -8.114 1.00 7.64 ? 173 SER A O 1 ATOM 1195 C CB . SER A 1 173 ? 39.445 61.279 -5.307 1.00 6.73 ? 173 SER A CB 1 ATOM 1196 O OG . SER A 1 173 ? 38.542 60.226 -4.993 1.00 9.02 ? 173 SER A OG 1 ATOM 1197 N N . HIS A 1 174 ? 40.686 61.260 -8.263 1.00 6.51 ? 174 HIS A N 1 ATOM 1198 C CA . HIS A 1 174 ? 41.196 60.376 -9.319 1.00 7.00 ? 174 HIS A CA 1 ATOM 1199 C C . HIS A 1 174 ? 41.851 59.177 -8.617 1.00 5.64 ? 174 HIS A C 1 ATOM 1200 O O . HIS A 1 174 ? 42.496 59.346 -7.608 1.00 4.22 ? 174 HIS A O 1 ATOM 1201 C CB . HIS A 1 174 ? 42.205 61.104 -10.186 1.00 7.18 ? 174 HIS A CB 1 ATOM 1202 C CG . HIS A 1 174 ? 42.438 60.428 -11.492 1.00 6.79 ? 174 HIS A CG 1 ATOM 1203 N ND1 . HIS A 1 174 ? 43.119 59.232 -11.594 1.00 6.73 ? 174 HIS A ND1 1 ATOM 1204 C CD2 . HIS A 1 174 ? 41.987 60.717 -12.737 1.00 7.15 ? 174 HIS A CD2 1 ATOM 1205 C CE1 . HIS A 1 174 ? 43.074 58.812 -12.848 1.00 6.73 ? 174 HIS A CE1 1 ATOM 1206 N NE2 . HIS A 1 174 ? 42.393 59.693 -13.560 1.00 6.76 ? 174 HIS A NE2 1 ATOM 1207 N N . TRP A 1 175 ? 41.682 57.968 -9.147 1.00 5.21 ? 175 TRP A N 1 ATOM 1208 C CA . TRP A 1 175 ? 42.241 56.814 -8.487 1.00 5.70 ? 175 TRP A CA 1 ATOM 1209 C C . TRP A 1 175 ? 43.721 56.990 -8.301 1.00 6.01 ? 175 TRP A C 1 ATOM 1210 O O . TRP A 1 175 ? 44.288 56.491 -7.310 1.00 6.77 ? 175 TRP A O 1 ATOM 1211 C CB . TRP A 1 175 ? 41.943 55.520 -9.264 1.00 6.30 ? 175 TRP A CB 1 ATOM 1212 C CG . TRP A 1 175 ? 42.768 55.324 -10.536 1.00 6.95 ? 175 TRP A CG 1 ATOM 1213 C CD1 . TRP A 1 175 ? 42.427 55.685 -11.805 1.00 7.65 ? 175 TRP A CD1 1 ATOM 1214 C CD2 . TRP A 1 175 ? 44.080 54.722 -10.626 1.00 8.32 ? 175 TRP A CD2 1 ATOM 1215 N NE1 . TRP A 1 175 ? 43.453 55.347 -12.693 1.00 7.04 ? 175 TRP A NE1 1 ATOM 1216 C CE2 . TRP A 1 175 ? 44.470 54.756 -11.997 1.00 6.85 ? 175 TRP A CE2 1 ATOM 1217 C CE3 . TRP A 1 175 ? 44.961 54.150 -9.678 1.00 7.29 ? 175 TRP A CE3 1 ATOM 1218 C CZ2 . TRP A 1 175 ? 45.703 54.239 -12.451 1.00 6.90 ? 175 TRP A CZ2 1 ATOM 1219 C CZ3 . TRP A 1 175 ? 46.194 53.629 -10.139 1.00 8.55 ? 175 TRP A CZ3 1 ATOM 1220 C CH2 . TRP A 1 175 ? 46.544 53.683 -11.515 1.00 7.39 ? 175 TRP A CH2 1 ATOM 1221 N N . ARG A 1 176 ? 44.377 57.706 -9.215 1.00 6.05 ? 176 ARG A N 1 ATOM 1222 C CA . ARG A 1 176 ? 45.811 57.897 -9.042 1.00 6.20 ? 176 ARG A CA 1 ATOM 1223 C C . ARG A 1 176 ? 46.159 58.639 -7.733 1.00 7.33 ? 176 ARG A C 1 ATOM 1224 O O . ARG A 1 176 ? 47.170 58.305 -7.040 1.00 7.70 ? 176 ARG A O 1 ATOM 1225 C CB . ARG A 1 176 ? 46.400 58.616 -10.274 1.00 6.79 ? 176 ARG A CB 1 ATOM 1226 C CG . ARG A 1 176 ? 46.430 57.727 -11.533 1.00 7.64 ? 176 ARG A CG 1 ATOM 1227 C CD . ARG A 1 176 ? 46.424 58.546 -12.818 1.00 9.48 ? 176 ARG A CD 1 ATOM 1228 N NE . ARG A 1 176 ? 47.510 59.520 -12.899 1.00 10.39 ? 176 ARG A NE 1 ATOM 1229 C CZ . ARG A 1 176 ? 47.681 60.367 -13.925 1.00 10.81 ? 176 ARG A CZ 1 ATOM 1230 N NH1 . ARG A 1 176 ? 46.845 60.352 -14.958 1.00 8.86 ? 176 ARG A NH1 1 ATOM 1231 N NH2 . ARG A 1 176 ? 48.667 61.258 -13.894 1.00 9.61 ? 176 ARG A NH2 1 ATOM 1232 N N . ASN A 1 177 ? 45.362 59.642 -7.384 1.00 5.82 ? 177 ASN A N 1 ATOM 1233 C CA . ASN A 1 177 ? 45.609 60.415 -6.154 1.00 6.28 ? 177 ASN A CA 1 ATOM 1234 C C . ASN A 1 177 ? 45.119 59.687 -4.907 1.00 6.62 ? 177 ASN A C 1 ATOM 1235 O O . ASN A 1 177 ? 45.608 59.930 -3.773 1.00 7.44 ? 177 ASN A O 1 ATOM 1236 C CB . ASN A 1 177 ? 44.980 61.811 -6.266 1.00 4.90 ? 177 ASN A CB 1 ATOM 1237 C CG . ASN A 1 177 ? 45.656 62.640 -7.331 1.00 7.27 ? 177 ASN A CG 1 ATOM 1238 O OD1 . ASN A 1 177 ? 46.815 62.398 -7.651 1.00 8.87 ? 177 ASN A OD1 1 ATOM 1239 N ND2 . ASN A 1 177 ? 44.939 63.594 -7.905 1.00 10.16 ? 177 ASN A ND2 1 ATOM 1240 N N . VAL A 1 178 ? 44.137 58.808 -5.100 1.00 6.41 ? 178 VAL A N 1 ATOM 1241 C CA . VAL A 1 178 ? 43.664 58.004 -3.978 1.00 5.88 ? 178 VAL A CA 1 ATOM 1242 C C . VAL A 1 178 ? 44.854 57.061 -3.621 1.00 6.70 ? 178 VAL A C 1 ATOM 1243 O O . VAL A 1 178 ? 45.161 56.841 -2.440 1.00 5.94 ? 178 VAL A O 1 ATOM 1244 C CB . VAL A 1 178 ? 42.418 57.159 -4.367 1.00 6.62 ? 178 VAL A CB 1 ATOM 1245 C CG1 . VAL A 1 178 ? 42.144 56.108 -3.277 1.00 6.85 ? 178 VAL A CG1 1 ATOM 1246 C CG2 . VAL A 1 178 ? 41.176 58.092 -4.520 1.00 6.81 ? 178 VAL A CG2 1 ATOM 1247 N N . LEU A 1 179 ? 45.504 56.482 -4.638 1.00 4.35 ? 179 LEU A N 1 ATOM 1248 C CA . LEU A 1 179 ? 46.643 55.605 -4.383 1.00 6.57 ? 179 LEU A CA 1 ATOM 1249 C C . LEU A 1 179 ? 47.788 56.442 -3.794 1.00 7.07 ? 179 LEU A C 1 ATOM 1250 O O . LEU A 1 179 ? 48.454 56.039 -2.842 1.00 8.26 ? 179 LEU A O 1 ATOM 1251 C CB . LEU A 1 179 ? 47.136 54.937 -5.691 1.00 7.26 ? 179 LEU A CB 1 ATOM 1252 C CG . LEU A 1 179 ? 48.420 54.079 -5.519 1.00 6.82 ? 179 LEU A CG 1 ATOM 1253 C CD1 . LEU A 1 179 ? 48.197 52.971 -4.478 1.00 4.84 ? 179 LEU A CD1 1 ATOM 1254 C CD2 . LEU A 1 179 ? 48.815 53.471 -6.873 1.00 6.19 ? 179 LEU A CD2 1 ATOM 1255 N N . LEU A 1 180 ? 48.013 57.631 -4.360 1.00 7.09 ? 180 LEU A N 1 ATOM 1256 C CA . LEU A 1 180 ? 49.078 58.480 -3.872 1.00 8.01 ? 180 LEU A CA 1 ATOM 1257 C C . LEU A 1 180 ? 48.939 58.738 -2.353 1.00 8.53 ? 180 LEU A C 1 ATOM 1258 O O . LEU A 1 180 ? 49.902 58.544 -1.591 1.00 7.41 ? 180 LEU A O 1 ATOM 1259 C CB . LEU A 1 180 ? 49.061 59.822 -4.597 1.00 7.77 ? 180 LEU A CB 1 ATOM 1260 C CG . LEU A 1 180 ? 50.184 60.785 -4.212 1.00 8.24 ? 180 LEU A CG 1 ATOM 1261 C CD1 . LEU A 1 180 ? 51.477 60.232 -4.801 1.00 8.00 ? 180 LEU A CD1 1 ATOM 1262 C CD2 . LEU A 1 180 ? 49.906 62.187 -4.721 1.00 5.88 ? 180 LEU A CD2 1 ATOM 1263 N N . GLN A 1 181 ? 47.752 59.163 -1.911 1.00 8.43 ? 181 GLN A N 1 ATOM 1264 C CA . GLN A 1 181 ? 47.575 59.491 -0.489 1.00 7.67 ? 181 GLN A CA 1 ATOM 1265 C C . GLN A 1 181 ? 47.616 58.270 0.392 1.00 7.52 ? 181 GLN A C 1 ATOM 1266 O O . GLN A 1 181 ? 48.110 58.357 1.508 1.00 7.19 ? 181 GLN A O 1 ATOM 1267 C CB . GLN A 1 181 ? 46.293 60.320 -0.251 1.00 7.38 ? 181 GLN A CB 1 ATOM 1268 C CG . GLN A 1 181 ? 44.970 59.624 -0.484 1.00 7.53 ? 181 GLN A CG 1 ATOM 1269 C CD . GLN A 1 181 ? 44.592 58.678 0.655 1.00 9.27 ? 181 GLN A CD 1 ATOM 1270 O OE1 . GLN A 1 181 ? 44.846 58.965 1.819 1.00 8.56 ? 181 GLN A OE1 1 ATOM 1271 N NE2 . GLN A 1 181 ? 43.968 57.562 0.317 1.00 7.53 ? 181 GLN A NE2 1 ATOM 1272 N N . LEU A 1 182 ? 47.112 57.134 -0.105 1.00 5.60 ? 182 LEU A N 1 ATOM 1273 C CA . LEU A 1 182 ? 47.166 55.893 0.651 1.00 5.63 ? 182 LEU A CA 1 ATOM 1274 C C . LEU A 1 182 ? 48.638 55.518 0.871 1.00 5.65 ? 182 LEU A C 1 ATOM 1275 O O . LEU A 1 182 ? 49.058 55.164 1.967 1.00 5.37 ? 182 LEU A O 1 ATOM 1276 C CB . LEU A 1 182 ? 46.487 54.734 -0.120 1.00 3.63 ? 182 LEU A CB 1 ATOM 1277 C CG . LEU A 1 182 ? 46.576 53.369 0.560 1.00 4.48 ? 182 LEU A CG 1 ATOM 1278 C CD1 . LEU A 1 182 ? 45.774 53.385 1.900 1.00 3.30 ? 182 LEU A CD1 1 ATOM 1279 C CD2 . LEU A 1 182 ? 46.003 52.260 -0.370 1.00 4.79 ? 182 LEU A CD2 1 ATOM 1280 N N . THR A 1 183 ? 49.422 55.614 -0.197 1.00 6.51 ? 183 THR A N 1 ATOM 1281 C CA . THR A 1 183 ? 50.829 55.267 -0.142 1.00 7.56 ? 183 THR A CA 1 ATOM 1282 C C . THR A 1 183 ? 51.591 56.229 0.798 1.00 8.63 ? 183 THR A C 1 ATOM 1283 O O . THR A 1 183 ? 52.507 55.810 1.520 1.00 10.21 ? 183 THR A O 1 ATOM 1284 C CB . THR A 1 183 ? 51.505 55.315 -1.579 1.00 7.80 ? 183 THR A CB 1 ATOM 1285 O OG1 . THR A 1 183 ? 50.817 54.438 -2.479 1.00 7.56 ? 183 THR A OG1 1 ATOM 1286 C CG2 . THR A 1 183 ? 53.004 54.863 -1.506 1.00 6.66 ? 183 THR A CG2 1 ATOM 1287 N N . GLU A 1 184 ? 51.237 57.503 0.776 1.00 8.23 ? 184 GLU A N 1 ATOM 1288 C CA . GLU A 1 184 ? 51.939 58.472 1.613 1.00 9.54 ? 184 GLU A CA 1 ATOM 1289 C C . GLU A 1 184 ? 51.747 58.126 3.105 1.00 8.64 ? 184 GLU A C 1 ATOM 1290 O O . GLU A 1 184 ? 52.695 58.138 3.888 1.00 10.08 ? 184 GLU A O 1 ATOM 1291 C CB . GLU A 1 184 ? 51.402 59.875 1.328 1.00 9.30 ? 184 GLU A CB 1 ATOM 1292 C CG . GLU A 1 184 ? 52.254 61.005 1.856 1.00 11.95 ? 184 GLU A CG 1 ATOM 1293 C CD . GLU A 1 184 ? 53.651 61.080 1.196 1.00 12.75 ? 184 GLU A CD 1 ATOM 1294 O OE1 . GLU A 1 184 ? 53.805 60.759 0.002 1.00 12.77 ? 184 GLU A OE1 1 ATOM 1295 O OE2 . GLU A 1 184 ? 54.595 61.467 1.890 1.00 14.83 ? 184 GLU A OE2 1 ATOM 1296 N N . GLY A 1 185 ? 50.526 57.806 3.491 1.00 6.95 ? 185 GLY A N 1 ATOM 1297 C CA . GLY A 1 185 ? 50.278 57.469 4.886 1.00 7.70 ? 185 GLY A CA 1 ATOM 1298 C C . GLY A 1 185 ? 50.853 56.116 5.293 1.00 8.09 ? 185 GLY A C 1 ATOM 1299 O O . GLY A 1 185 ? 51.436 55.966 6.385 1.00 7.61 ? 185 GLY A O 1 ATOM 1300 N N . GLN A 1 186 ? 50.688 55.120 4.431 1.00 7.49 ? 186 GLN A N 1 ATOM 1301 C CA . GLN A 1 186 ? 51.206 53.788 4.751 1.00 9.19 ? 186 GLN A CA 1 ATOM 1302 C C . GLN A 1 186 ? 52.748 53.704 4.731 1.00 9.71 ? 186 GLN A C 1 ATOM 1303 O O . GLN A 1 186 ? 53.331 52.915 5.471 1.00 9.49 ? 186 GLN A O 1 ATOM 1304 C CB . GLN A 1 186 ? 50.592 52.716 3.819 1.00 9.76 ? 186 GLN A CB 1 ATOM 1305 C CG . GLN A 1 186 ? 49.059 52.497 4.079 1.00 11.39 ? 186 GLN A CG 1 ATOM 1306 C CD . GLN A 1 186 ? 48.619 51.097 3.727 1.00 11.00 ? 186 GLN A CD 1 ATOM 1307 O OE1 . GLN A 1 186 ? 49.275 50.434 2.938 1.00 13.74 ? 186 GLN A OE1 1 ATOM 1308 N NE2 . GLN A 1 186 ? 47.526 50.633 4.311 1.00 11.77 ? 186 GLN A NE2 1 ATOM 1309 N N . THR A 1 187 ? 53.401 54.508 3.892 1.00 9.16 ? 187 THR A N 1 ATOM 1310 C CA . THR A 1 187 ? 54.848 54.484 3.861 1.00 8.00 ? 187 THR A CA 1 ATOM 1311 C C . THR A 1 187 ? 55.346 55.085 5.195 1.00 8.97 ? 187 THR A C 1 ATOM 1312 O O . THR A 1 187 ? 56.278 54.580 5.803 1.00 8.83 ? 187 THR A O 1 ATOM 1313 C CB . THR A 1 187 ? 55.366 55.249 2.650 1.00 9.01 ? 187 THR A CB 1 ATOM 1314 O OG1 . THR A 1 187 ? 54.897 54.585 1.455 1.00 7.14 ? 187 THR A OG1 1 ATOM 1315 C CG2 . THR A 1 187 ? 56.919 55.267 2.637 1.00 6.28 ? 187 THR A CG2 1 ATOM 1316 N N . TRP A 1 188 ? 54.701 56.140 5.657 1.00 9.29 ? 188 TRP A N 1 ATOM 1317 C CA . TRP A 1 188 ? 55.060 56.747 6.925 1.00 10.03 ? 188 TRP A CA 1 ATOM 1318 C C . TRP A 1 188 ? 54.825 55.689 8.037 1.00 10.48 ? 188 TRP A C 1 ATOM 1319 O O . TRP A 1 188 ? 55.694 55.450 8.880 1.00 9.94 ? 188 TRP A O 1 ATOM 1320 C CB . TRP A 1 188 ? 54.182 57.992 7.195 1.00 11.14 ? 188 TRP A CB 1 ATOM 1321 C CG . TRP A 1 188 ? 54.624 58.780 8.422 1.00 11.39 ? 188 TRP A CG 1 ATOM 1322 C CD1 . TRP A 1 188 ? 55.533 59.813 8.463 1.00 11.47 ? 188 TRP A CD1 1 ATOM 1323 C CD2 . TRP A 1 188 ? 54.287 58.490 9.790 1.00 11.15 ? 188 TRP A CD2 1 ATOM 1324 N NE1 . TRP A 1 188 ? 55.790 60.161 9.767 1.00 9.68 ? 188 TRP A NE1 1 ATOM 1325 C CE2 . TRP A 1 188 ? 55.044 59.374 10.603 1.00 10.62 ? 188 TRP A CE2 1 ATOM 1326 C CE3 . TRP A 1 188 ? 53.435 57.564 10.402 1.00 8.95 ? 188 TRP A CE3 1 ATOM 1327 C CZ2 . TRP A 1 188 ? 54.973 59.363 12.005 1.00 8.92 ? 188 TRP A CZ2 1 ATOM 1328 C CZ3 . TRP A 1 188 ? 53.364 57.542 11.824 1.00 12.44 ? 188 TRP A CZ3 1 ATOM 1329 C CH2 . TRP A 1 188 ? 54.137 58.448 12.597 1.00 11.44 ? 188 TRP A CH2 1 ATOM 1330 N N . LEU A 1 189 ? 53.659 55.039 8.030 1.00 9.61 ? 189 LEU A N 1 ATOM 1331 C CA . LEU A 1 189 ? 53.356 54.050 9.069 1.00 10.74 ? 189 LEU A CA 1 ATOM 1332 C C . LEU A 1 189 ? 54.357 52.900 9.111 1.00 11.02 ? 189 LEU A C 1 ATOM 1333 O O . LEU A 1 189 ? 54.779 52.474 10.196 1.00 12.24 ? 189 LEU A O 1 ATOM 1334 C CB . LEU A 1 189 ? 51.934 53.474 8.892 1.00 10.64 ? 189 LEU A CB 1 ATOM 1335 C CG . LEU A 1 189 ? 50.776 54.347 9.417 1.00 10.09 ? 189 LEU A CG 1 ATOM 1336 C CD1 . LEU A 1 189 ? 49.443 53.603 9.117 1.00 10.13 ? 189 LEU A CD1 1 ATOM 1337 C CD2 . LEU A 1 189 ? 50.930 54.550 10.984 1.00 8.04 ? 189 LEU A CD2 1 ATOM 1338 N N . LYS A 1 190 ? 54.734 52.382 7.949 1.00 11.01 ? 190 LYS A N 1 ATOM 1339 C CA . LYS A 1 190 ? 55.694 51.271 7.937 1.00 13.55 ? 190 LYS A CA 1 ATOM 1340 C C . LYS A 1 190 ? 57.018 51.726 8.533 1.00 13.26 ? 190 LYS A C 1 ATOM 1341 O O . LYS A 1 190 ? 57.625 51.054 9.346 1.00 12.19 ? 190 LYS A O 1 ATOM 1342 C CB . LYS A 1 190 ? 55.997 50.777 6.509 1.00 15.43 ? 190 LYS A CB 1 ATOM 1343 C CG . LYS A 1 190 ? 56.850 49.478 6.512 1.00 14.85 ? 190 LYS A CG 1 ATOM 1344 C CD . LYS A 1 190 ? 56.984 48.926 5.136 1.00 18.30 ? 190 LYS A CD 1 ATOM 1345 C CE . LYS A 1 190 ? 57.861 47.655 5.104 1.00 21.93 ? 190 LYS A CE 1 ATOM 1346 N NZ . LYS A 1 190 ? 58.267 47.357 3.672 1.00 22.19 ? 190 LYS A NZ 1 ATOM 1347 N N . GLN A 1 191 ? 57.446 52.897 8.115 1.00 13.23 ? 191 GLN A N 1 ATOM 1348 C CA . GLN A 1 191 ? 58.713 53.412 8.558 1.00 15.34 ? 191 GLN A CA 1 ATOM 1349 C C . GLN A 1 191 ? 58.808 53.704 10.048 1.00 14.72 ? 191 GLN A C 1 ATOM 1350 O O . GLN A 1 191 ? 59.758 53.287 10.710 1.00 15.13 ? 191 GLN A O 1 ATOM 1351 C CB . GLN A 1 191 ? 59.031 54.680 7.790 1.00 16.55 ? 191 GLN A CB 1 ATOM 1352 C CG . GLN A 1 191 ? 60.477 55.085 7.883 1.00 22.90 ? 191 GLN A CG 1 ATOM 1353 C CD . GLN A 1 191 ? 60.720 56.446 7.251 1.00 25.99 ? 191 GLN A CD 1 ATOM 1354 O OE1 . GLN A 1 191 ? 60.049 56.838 6.269 1.00 28.53 ? 191 GLN A OE1 1 ATOM 1355 N NE2 . GLN A 1 191 ? 61.678 57.183 7.811 1.00 28.37 ? 191 GLN A NE2 1 ATOM 1356 N N . PHE A 1 192 ? 57.835 54.439 10.574 1.00 13.84 ? 192 PHE A N 1 ATOM 1357 C CA . PHE A 1 192 ? 57.860 54.823 11.968 1.00 13.91 ? 192 PHE A CA 1 ATOM 1358 C C . PHE A 1 192 ? 57.069 54.002 12.973 1.00 14.70 ? 192 PHE A C 1 ATOM 1359 O O . PHE A 1 192 ? 57.381 54.040 14.165 1.00 14.60 ? 192 PHE A O 1 ATOM 1360 C CB . PHE A 1 192 ? 57.423 56.279 12.092 1.00 12.43 ? 192 PHE A CB 1 ATOM 1361 C CG . PHE A 1 192 ? 58.323 57.223 11.377 1.00 14.59 ? 192 PHE A CG 1 ATOM 1362 C CD1 . PHE A 1 192 ? 58.007 57.667 10.087 1.00 13.13 ? 192 PHE A CD1 1 ATOM 1363 C CD2 . PHE A 1 192 ? 59.519 57.656 11.974 1.00 14.60 ? 192 PHE A CD2 1 ATOM 1364 C CE1 . PHE A 1 192 ? 58.849 58.524 9.401 1.00 13.93 ? 192 PHE A CE1 1 ATOM 1365 C CE2 . PHE A 1 192 ? 60.382 58.527 11.276 1.00 15.06 ? 192 PHE A CE2 1 ATOM 1366 C CZ . PHE A 1 192 ? 60.037 58.958 9.990 1.00 14.48 ? 192 PHE A CZ 1 ATOM 1367 N N . MET A 1 193 ? 56.025 53.316 12.530 1.00 13.30 ? 193 MET A N 1 ATOM 1368 C CA . MET A 1 193 ? 55.210 52.535 13.464 1.00 14.07 ? 193 MET A CA 1 ATOM 1369 C C . MET A 1 193 ? 55.366 51.045 13.189 1.00 13.49 ? 193 MET A C 1 ATOM 1370 O O . MET A 1 193 ? 54.858 50.207 13.948 1.00 13.81 ? 193 MET A O 1 ATOM 1371 C CB . MET A 1 193 ? 53.723 52.925 13.337 1.00 14.96 ? 193 MET A CB 1 ATOM 1372 C CG . MET A 1 193 ? 53.338 54.298 13.899 1.00 17.41 ? 193 MET A CG 1 ATOM 1373 S SD . MET A 1 193 ? 53.618 54.427 15.730 1.00 24.09 ? 193 MET A SD 1 ATOM 1374 C CE . MET A 1 193 ? 55.041 55.473 15.528 1.00 21.33 ? 193 MET A CE 1 ATOM 1375 N N . ASN A 1 194 ? 56.030 50.717 12.082 1.00 13.75 ? 194 ASN A N 1 ATOM 1376 C CA . ASN A 1 194 ? 56.272 49.326 11.707 1.00 15.81 ? 194 ASN A CA 1 ATOM 1377 C C . ASN A 1 194 ? 54.955 48.515 11.573 1.00 15.75 ? 194 ASN A C 1 ATOM 1378 O O . ASN A 1 194 ? 54.875 47.377 12.029 1.00 15.99 ? 194 ASN A O 1 ATOM 1379 C CB . ASN A 1 194 ? 57.210 48.703 12.761 1.00 19.88 ? 194 ASN A CB 1 ATOM 1380 C CG . ASN A 1 194 ? 57.541 47.249 12.482 1.00 25.90 ? 194 ASN A CG 1 ATOM 1381 O OD1 . ASN A 1 194 ? 57.777 46.864 11.342 1.00 25.29 ? 194 ASN A OD1 1 ATOM 1382 N ND2 . ASN A 1 194 ? 57.534 46.483 13.572 1.00 33.09 ? 194 ASN A ND2 1 ATOM 1383 N N . VAL A 1 195 ? 53.926 49.123 10.980 1.00 14.20 ? 195 VAL A N 1 ATOM 1384 C CA . VAL A 1 195 ? 52.631 48.468 10.764 1.00 13.18 ? 195 VAL A CA 1 ATOM 1385 C C . VAL A 1 195 ? 52.027 48.909 9.434 1.00 12.26 ? 195 VAL A C 1 ATOM 1386 O O . VAL A 1 195 ? 52.239 50.044 8.997 1.00 10.05 ? 195 VAL A O 1 ATOM 1387 C CB . VAL A 1 195 ? 51.559 48.790 11.872 1.00 15.16 ? 195 VAL A CB 1 ATOM 1388 C CG1 . VAL A 1 195 ? 52.017 48.261 13.249 1.00 17.23 ? 195 VAL A CG1 1 ATOM 1389 C CG2 . VAL A 1 195 ? 51.260 50.280 11.922 1.00 14.45 ? 195 VAL A CG2 1 ATOM 1390 N N . THR A 1 196 ? 51.270 48.000 8.825 1.00 10.47 ? 196 THR A N 1 ATOM 1391 C CA . THR A 1 196 ? 50.561 48.228 7.578 1.00 11.25 ? 196 THR A CA 1 ATOM 1392 C C . THR A 1 196 ? 49.099 47.765 7.764 1.00 11.45 ? 196 THR A C 1 ATOM 1393 O O . THR A 1 196 ? 48.822 46.563 7.799 1.00 9.91 ? 196 THR A O 1 ATOM 1394 C CB . THR A 1 196 ? 51.212 47.434 6.422 1.00 11.68 ? 196 THR A CB 1 ATOM 1395 O OG1 . THR A 1 196 ? 52.533 47.947 6.209 1.00 12.95 ? 196 THR A OG1 1 ATOM 1396 C CG2 . THR A 1 196 ? 50.410 47.591 5.149 1.00 11.61 ? 196 THR A CG2 1 ATOM 1397 N N . PRO A 1 197 ? 48.157 48.712 7.914 1.00 11.05 ? 197 PRO A N 1 ATOM 1398 C CA . PRO A 1 197 ? 46.734 48.373 8.096 1.00 12.11 ? 197 PRO A CA 1 ATOM 1399 C C . PRO A 1 197 ? 46.206 47.469 6.982 1.00 12.33 ? 197 PRO A C 1 ATOM 1400 O O . PRO A 1 197 ? 46.580 47.629 5.840 1.00 12.69 ? 197 PRO A O 1 ATOM 1401 C CB . PRO A 1 197 ? 46.041 49.725 8.053 1.00 11.96 ? 197 PRO A CB 1 ATOM 1402 C CG . PRO A 1 197 ? 47.090 50.651 8.656 1.00 11.86 ? 197 PRO A CG 1 ATOM 1403 C CD . PRO A 1 197 ? 48.390 50.157 8.064 1.00 11.45 ? 197 PRO A CD 1 ATOM 1404 N N . THR A 1 198 ? 45.371 46.492 7.326 1.00 11.84 ? 198 THR A N 1 ATOM 1405 C CA . THR A 1 198 ? 44.776 45.654 6.299 1.00 10.40 ? 198 THR A CA 1 ATOM 1406 C C . THR A 1 198 ? 43.264 45.812 6.386 1.00 9.11 ? 198 THR A C 1 ATOM 1407 O O . THR A 1 198 ? 42.542 45.141 5.654 1.00 7.99 ? 198 THR A O 1 ATOM 1408 C CB . THR A 1 198 ? 45.089 44.168 6.446 1.00 11.27 ? 198 THR A CB 1 ATOM 1409 O OG1 . THR A 1 198 ? 44.534 43.722 7.682 1.00 10.32 ? 198 THR A OG1 1 ATOM 1410 C CG2 . THR A 1 198 ? 46.619 43.900 6.359 1.00 10.79 ? 198 THR A CG2 1 ATOM 1411 N N . ALA A 1 199 ? 42.790 46.678 7.294 1.00 9.01 ? 199 ALA A N 1 ATOM 1412 C CA . ALA A 1 199 ? 41.364 46.973 7.388 1.00 8.15 ? 199 ALA A CA 1 ATOM 1413 C C . ALA A 1 199 ? 41.159 48.488 7.131 1.00 8.77 ? 199 ALA A C 1 ATOM 1414 O O . ALA A 1 199 ? 41.867 49.323 7.720 1.00 8.52 ? 199 ALA A O 1 ATOM 1415 C CB . ALA A 1 199 ? 40.804 46.598 8.795 1.00 8.45 ? 199 ALA A CB 1 ATOM 1416 N N . SER A 1 200 ? 40.171 48.839 6.307 1.00 7.32 ? 200 SER A N 1 ATOM 1417 C CA . SER A 1 200 ? 39.907 50.247 5.991 1.00 8.97 ? 200 SER A CA 1 ATOM 1418 C C . SER A 1 200 ? 38.656 50.730 6.697 1.00 9.37 ? 200 SER A C 1 ATOM 1419 O O . SER A 1 200 ? 37.736 49.951 6.953 1.00 10.38 ? 200 SER A O 1 ATOM 1420 C CB . SER A 1 200 ? 39.752 50.467 4.471 1.00 9.75 ? 200 SER A CB 1 ATOM 1421 O OG . SER A 1 200 ? 39.568 51.841 4.191 1.00 11.17 ? 200 SER A OG 1 ATOM 1422 N N . TRP A 1 201 ? 38.626 52.019 6.990 1.00 7.64 ? 201 TRP A N 1 ATOM 1423 C CA . TRP A 1 201 ? 37.538 52.641 7.724 1.00 8.97 ? 201 TRP A CA 1 ATOM 1424 C C . TRP A 1 201 ? 37.203 53.975 7.022 1.00 9.89 ? 201 TRP A C 1 ATOM 1425 O O . TRP A 1 201 ? 38.004 54.905 7.059 1.00 10.50 ? 201 TRP A O 1 ATOM 1426 C CB . TRP A 1 201 ? 38.038 52.887 9.155 1.00 8.60 ? 201 TRP A CB 1 ATOM 1427 C CG . TRP A 1 201 ? 37.174 53.752 10.078 1.00 10.44 ? 201 TRP A CG 1 ATOM 1428 C CD1 . TRP A 1 201 ? 37.289 55.098 10.295 1.00 10.74 ? 201 TRP A CD1 1 ATOM 1429 C CD2 . TRP A 1 201 ? 36.214 53.278 11.029 1.00 10.46 ? 201 TRP A CD2 1 ATOM 1430 N NE1 . TRP A 1 201 ? 36.479 55.496 11.343 1.00 11.43 ? 201 TRP A NE1 1 ATOM 1431 C CE2 . TRP A 1 201 ? 35.807 54.396 11.811 1.00 11.74 ? 201 TRP A CE2 1 ATOM 1432 C CE3 . TRP A 1 201 ? 35.662 52.021 11.302 1.00 10.44 ? 201 TRP A CE3 1 ATOM 1433 C CZ2 . TRP A 1 201 ? 34.878 54.288 12.842 1.00 11.82 ? 201 TRP A CZ2 1 ATOM 1434 C CZ3 . TRP A 1 201 ? 34.728 51.915 12.344 1.00 10.47 ? 201 TRP A CZ3 1 ATOM 1435 C CH2 . TRP A 1 201 ? 34.349 53.043 13.096 1.00 11.47 ? 201 TRP A CH2 1 ATOM 1436 N N . ALA A 1 202 ? 36.036 54.047 6.391 1.00 9.43 ? 202 ALA A N 1 ATOM 1437 C CA . ALA A 1 202 ? 35.642 55.253 5.669 1.00 9.72 ? 202 ALA A CA 1 ATOM 1438 C C . ALA A 1 202 ? 34.216 55.625 6.091 1.00 9.38 ? 202 ALA A C 1 ATOM 1439 O O . ALA A 1 202 ? 33.236 55.197 5.500 1.00 8.77 ? 202 ALA A O 1 ATOM 1440 C CB . ALA A 1 202 ? 35.738 55.010 4.136 1.00 8.68 ? 202 ALA A CB 1 ATOM 1441 N N . ILE A 1 203 ? 34.114 56.454 7.126 1.00 9.89 ? 203 ILE A N 1 ATOM 1442 C CA . ILE A 1 203 ? 32.815 56.780 7.664 1.00 9.26 ? 203 ILE A CA 1 ATOM 1443 C C . ILE A 1 203 ? 32.190 58.088 7.274 1.00 10.07 ? 203 ILE A C 1 ATOM 1444 O O . ILE A 1 203 ? 31.032 58.302 7.619 1.00 7.85 ? 203 ILE A O 1 ATOM 1445 C CB . ILE A 1 203 ? 32.838 56.679 9.219 1.00 9.84 ? 203 ILE A CB 1 ATOM 1446 C CG1 . ILE A 1 203 ? 33.913 57.613 9.790 1.00 10.36 ? 203 ILE A CG1 1 ATOM 1447 C CG2 . ILE A 1 203 ? 33.121 55.196 9.634 1.00 9.47 ? 203 ILE A CG2 1 ATOM 1448 C CD1 . ILE A 1 203 ? 33.823 57.856 11.319 1.00 10.15 ? 203 ILE A CD1 1 ATOM 1449 N N . ASP A 1 204 ? 32.921 58.971 6.581 1.00 9.60 ? 204 ASP A N 1 ATOM 1450 C CA . ASP A 1 204 ? 32.315 60.257 6.222 1.00 10.45 ? 204 ASP A CA 1 ATOM 1451 C C . ASP A 1 204 ? 32.210 60.671 4.750 1.00 10.42 ? 204 ASP A C 1 ATOM 1452 O O . ASP A 1 204 ? 31.538 61.664 4.453 1.00 11.41 ? 204 ASP A O 1 ATOM 1453 C CB . ASP A 1 204 ? 32.957 61.399 7.020 1.00 10.92 ? 204 ASP A CB 1 ATOM 1454 C CG . ASP A 1 204 ? 31.933 62.494 7.410 1.00 12.99 ? 204 ASP A CG 1 ATOM 1455 O OD1 . ASP A 1 204 ? 32.344 63.663 7.603 1.00 11.89 ? 204 ASP A OD1 1 ATOM 1456 O OD2 . ASP A 1 204 ? 30.721 62.174 7.548 1.00 10.38 ? 204 ASP A OD2 1 ATOM 1457 N N . PRO A 1 205 ? 32.899 59.976 3.809 1.00 11.29 ? 205 PRO A N 1 ATOM 1458 C CA . PRO A 1 205 ? 32.758 60.382 2.387 1.00 10.22 ? 205 PRO A CA 1 ATOM 1459 C C . PRO A 1 205 ? 31.261 60.290 2.046 1.00 10.66 ? 205 PRO A C 1 ATOM 1460 O O . PRO A 1 205 ? 30.552 59.433 2.585 1.00 9.84 ? 205 PRO A O 1 ATOM 1461 C CB . PRO A 1 205 ? 33.554 59.314 1.637 1.00 11.09 ? 205 PRO A CB 1 ATOM 1462 C CG . PRO A 1 205 ? 34.609 58.939 2.624 1.00 13.55 ? 205 PRO A CG 1 ATOM 1463 C CD . PRO A 1 205 ? 33.836 58.846 3.927 1.00 11.32 ? 205 PRO A CD 1 ATOM 1464 N N . PHE A 1 206 ? 30.796 61.141 1.127 1.00 10.70 ? 206 PHE A N 1 ATOM 1465 C CA . PHE A 1 206 ? 29.382 61.245 0.761 1.00 9.57 ? 206 PHE A CA 1 ATOM 1466 C C . PHE A 1 206 ? 29.020 60.270 -0.381 1.00 10.82 ? 206 PHE A C 1 ATOM 1467 O O . PHE A 1 206 ? 28.865 60.675 -1.526 1.00 10.44 ? 206 PHE A O 1 ATOM 1468 C CB . PHE A 1 206 ? 29.126 62.707 0.363 1.00 10.72 ? 206 PHE A CB 1 ATOM 1469 C CG . PHE A 1 206 ? 29.982 63.716 1.143 1.00 12.14 ? 206 PHE A CG 1 ATOM 1470 C CD1 . PHE A 1 206 ? 30.298 63.502 2.501 1.00 11.13 ? 206 PHE A CD1 1 ATOM 1471 C CD2 . PHE A 1 206 ? 30.492 64.866 0.508 1.00 12.74 ? 206 PHE A CD2 1 ATOM 1472 C CE1 . PHE A 1 206 ? 31.119 64.409 3.214 1.00 12.98 ? 206 PHE A CE1 1 ATOM 1473 C CE2 . PHE A 1 206 ? 31.316 65.780 1.217 1.00 12.19 ? 206 PHE A CE2 1 ATOM 1474 C CZ . PHE A 1 206 ? 31.630 65.548 2.565 1.00 11.88 ? 206 PHE A CZ 1 ATOM 1475 N N . GLY A 1 207 ? 28.864 58.989 -0.050 1.00 10.48 ? 207 GLY A N 1 ATOM 1476 C CA . GLY A 1 207 ? 28.633 57.987 -1.072 1.00 9.26 ? 207 GLY A CA 1 ATOM 1477 C C . GLY A 1 207 ? 29.993 57.298 -1.240 1.00 9.01 ? 207 GLY A C 1 ATOM 1478 O O . GLY A 1 207 ? 31.040 57.870 -0.951 1.00 8.54 ? 207 GLY A O 1 ATOM 1479 N N . HIS A 1 208 ? 29.986 56.075 -1.751 1.00 8.65 ? 208 HIS A N 1 ATOM 1480 C CA . HIS A 1 208 ? 31.203 55.284 -1.877 1.00 8.59 ? 208 HIS A CA 1 ATOM 1481 C C . HIS A 1 208 ? 31.405 54.696 -3.261 1.00 8.33 ? 208 HIS A C 1 ATOM 1482 O O . HIS A 1 208 ? 30.435 54.368 -3.962 1.00 7.70 ? 208 HIS A O 1 ATOM 1483 C CB . HIS A 1 208 ? 31.134 54.165 -0.840 1.00 9.27 ? 208 HIS A CB 1 ATOM 1484 C CG . HIS A 1 208 ? 31.244 54.655 0.571 1.00 10.23 ? 208 HIS A CG 1 ATOM 1485 N ND1 . HIS A 1 208 ? 32.462 54.919 1.167 1.00 9.21 ? 208 HIS A ND1 1 ATOM 1486 C CD2 . HIS A 1 208 ? 30.295 54.957 1.493 1.00 10.55 ? 208 HIS A CD2 1 ATOM 1487 C CE1 . HIS A 1 208 ? 32.255 55.364 2.396 1.00 9.86 ? 208 HIS A CE1 1 ATOM 1488 N NE2 . HIS A 1 208 ? 30.952 55.394 2.618 1.00 9.44 ? 208 HIS A NE2 1 ATOM 1489 N N . SER A 1 209 ? 32.670 54.562 -3.636 1.00 7.10 ? 209 SER A N 1 ATOM 1490 C CA . SER A 1 209 ? 33.062 54.052 -4.946 1.00 7.36 ? 209 SER A CA 1 ATOM 1491 C C . SER A 1 209 ? 33.794 52.725 -4.843 1.00 6.96 ? 209 SER A C 1 ATOM 1492 O O . SER A 1 209 ? 34.570 52.540 -3.904 1.00 6.37 ? 209 SER A O 1 ATOM 1493 C CB . SER A 1 209 ? 34.021 55.041 -5.591 1.00 6.08 ? 209 SER A CB 1 ATOM 1494 O OG . SER A 1 209 ? 34.605 54.451 -6.741 1.00 9.29 ? 209 SER A OG 1 ATOM 1495 N N . PRO A 1 210 ? 33.576 51.804 -5.820 1.00 6.71 ? 210 PRO A N 1 ATOM 1496 C CA . PRO A 1 210 ? 34.229 50.487 -5.845 1.00 6.36 ? 210 PRO A CA 1 ATOM 1497 C C . PRO A 1 210 ? 35.699 50.674 -6.205 1.00 7.86 ? 210 PRO A C 1 ATOM 1498 O O . PRO A 1 210 ? 36.465 49.727 -6.162 1.00 7.74 ? 210 PRO A O 1 ATOM 1499 C CB . PRO A 1 210 ? 33.466 49.706 -6.924 1.00 6.15 ? 210 PRO A CB 1 ATOM 1500 C CG . PRO A 1 210 ? 32.951 50.763 -7.835 1.00 4.46 ? 210 PRO A CG 1 ATOM 1501 C CD . PRO A 1 210 ? 32.568 51.906 -6.895 1.00 5.12 ? 210 PRO A CD 1 ATOM 1502 N N . THR A 1 211 ? 36.092 51.891 -6.570 1.00 7.53 ? 211 THR A N 1 ATOM 1503 C CA . THR A 1 211 ? 37.518 52.111 -6.822 1.00 8.93 ? 211 THR A CA 1 ATOM 1504 C C . THR A 1 211 ? 38.315 51.861 -5.502 1.00 7.76 ? 211 THR A C 1 ATOM 1505 O O . THR A 1 211 ? 39.500 51.461 -5.539 1.00 8.14 ? 211 THR A O 1 ATOM 1506 C CB . THR A 1 211 ? 37.802 53.580 -7.319 1.00 9.37 ? 211 THR A CB 1 ATOM 1507 O OG1 . THR A 1 211 ? 37.202 53.764 -8.613 1.00 9.22 ? 211 THR A OG1 1 ATOM 1508 C CG2 . THR A 1 211 ? 39.328 53.835 -7.443 1.00 7.13 ? 211 THR A CG2 1 ATOM 1509 N N . MET A 1 212 ? 37.674 52.072 -4.345 1.00 6.86 ? 212 MET A N 1 ATOM 1510 C CA . MET A 1 212 ? 38.360 51.874 -3.056 1.00 7.17 ? 212 MET A CA 1 ATOM 1511 C C . MET A 1 212 ? 38.716 50.397 -2.857 1.00 7.03 ? 212 MET A C 1 ATOM 1512 O O . MET A 1 212 ? 39.885 50.084 -2.673 1.00 6.76 ? 212 MET A O 1 ATOM 1513 C CB . MET A 1 212 ? 37.534 52.413 -1.883 1.00 8.18 ? 212 MET A CB 1 ATOM 1514 C CG . MET A 1 212 ? 37.194 53.892 -2.010 1.00 11.08 ? 212 MET A CG 1 ATOM 1515 S SD . MET A 1 212 ? 38.681 54.960 -2.303 1.00 14.23 ? 212 MET A SD 1 ATOM 1516 C CE . MET A 1 212 ? 39.523 54.796 -0.696 1.00 10.64 ? 212 MET A CE 1 ATOM 1517 N N . PRO A 1 213 ? 37.738 49.472 -2.878 1.00 8.02 ? 213 PRO A N 1 ATOM 1518 C CA . PRO A 1 213 ? 38.177 48.081 -2.710 1.00 7.43 ? 213 PRO A CA 1 ATOM 1519 C C . PRO A 1 213 ? 39.152 47.669 -3.831 1.00 8.81 ? 213 PRO A C 1 ATOM 1520 O O . PRO A 1 213 ? 40.017 46.803 -3.638 1.00 8.23 ? 213 PRO A O 1 ATOM 1521 C CB . PRO A 1 213 ? 36.872 47.287 -2.762 1.00 7.51 ? 213 PRO A CB 1 ATOM 1522 C CG . PRO A 1 213 ? 35.917 48.224 -3.518 1.00 8.37 ? 213 PRO A CG 1 ATOM 1523 C CD . PRO A 1 213 ? 36.261 49.538 -2.849 1.00 8.86 ? 213 PRO A CD 1 ATOM 1524 N N . TYR A 1 214 ? 39.005 48.251 -5.022 1.00 8.68 ? 214 TYR A N 1 ATOM 1525 C CA . TYR A 1 214 ? 39.921 47.905 -6.119 1.00 7.58 ? 214 TYR A CA 1 ATOM 1526 C C . TYR A 1 214 ? 41.385 48.143 -5.711 1.00 8.53 ? 214 TYR A C 1 ATOM 1527 O O . TYR A 1 214 ? 42.245 47.242 -5.823 1.00 7.70 ? 214 TYR A O 1 ATOM 1528 C CB . TYR A 1 214 ? 39.646 48.742 -7.349 1.00 8.99 ? 214 TYR A CB 1 ATOM 1529 C CG . TYR A 1 214 ? 40.588 48.439 -8.510 1.00 11.36 ? 214 TYR A CG 1 ATOM 1530 C CD1 . TYR A 1 214 ? 40.350 47.360 -9.367 1.00 12.25 ? 214 TYR A CD1 1 ATOM 1531 C CD2 . TYR A 1 214 ? 41.668 49.278 -8.799 1.00 10.40 ? 214 TYR A CD2 1 ATOM 1532 C CE1 . TYR A 1 214 ? 41.159 47.151 -10.501 1.00 14.27 ? 214 TYR A CE1 1 ATOM 1533 C CE2 . TYR A 1 214 ? 42.472 49.077 -9.913 1.00 10.73 ? 214 TYR A CE2 1 ATOM 1534 C CZ . TYR A 1 214 ? 42.219 48.023 -10.772 1.00 13.64 ? 214 TYR A CZ 1 ATOM 1535 O OH . TYR A 1 214 ? 43.007 47.850 -11.919 1.00 12.19 ? 214 TYR A OH 1 ATOM 1536 N N . ILE A 1 215 ? 41.667 49.370 -5.268 1.00 7.83 ? 215 ILE A N 1 ATOM 1537 C CA . ILE A 1 215 ? 43.008 49.769 -4.836 1.00 7.54 ? 215 ILE A CA 1 ATOM 1538 C C . ILE A 1 215 ? 43.415 49.050 -3.532 1.00 7.90 ? 215 ILE A C 1 ATOM 1539 O O . ILE A 1 215 ? 44.539 48.548 -3.387 1.00 6.89 ? 215 ILE A O 1 ATOM 1540 C CB . ILE A 1 215 ? 43.062 51.336 -4.608 1.00 8.78 ? 215 ILE A CB 1 ATOM 1541 C CG1 . ILE A 1 215 ? 42.801 52.054 -5.935 1.00 7.96 ? 215 ILE A CG1 1 ATOM 1542 C CG2 . ILE A 1 215 ? 44.436 51.758 -3.995 1.00 8.24 ? 215 ILE A CG2 1 ATOM 1543 C CD1 . ILE A 1 215 ? 42.831 53.555 -5.843 1.00 11.46 ? 215 ILE A CD1 1 ATOM 1544 N N . LEU A 1 216 ? 42.488 48.973 -2.590 1.00 6.40 ? 216 LEU A N 1 ATOM 1545 C CA . LEU A 1 216 ? 42.810 48.355 -1.308 1.00 7.88 ? 216 LEU A CA 1 ATOM 1546 C C . LEU A 1 216 ? 43.158 46.871 -1.452 1.00 8.86 ? 216 LEU A C 1 ATOM 1547 O O . LEU A 1 216 ? 44.133 46.392 -0.852 1.00 9.70 ? 216 LEU A O 1 ATOM 1548 C CB . LEU A 1 216 ? 41.622 48.523 -0.338 1.00 6.31 ? 216 LEU A CB 1 ATOM 1549 C CG . LEU A 1 216 ? 41.265 50.000 0.024 1.00 7.79 ? 216 LEU A CG 1 ATOM 1550 C CD1 . LEU A 1 216 ? 39.960 50.001 0.858 1.00 5.12 ? 216 LEU A CD1 1 ATOM 1551 C CD2 . LEU A 1 216 ? 42.433 50.693 0.839 1.00 4.19 ? 216 LEU A CD2 1 ATOM 1552 N N . GLN A 1 217 ? 42.370 46.146 -2.233 1.00 8.14 ? 217 GLN A N 1 ATOM 1553 C CA . GLN A 1 217 ? 42.625 44.719 -2.384 1.00 9.33 ? 217 GLN A CA 1 ATOM 1554 C C . GLN A 1 217 ? 43.980 44.489 -3.053 1.00 10.08 ? 217 GLN A C 1 ATOM 1555 O O . GLN A 1 217 ? 44.624 43.451 -2.829 1.00 9.98 ? 217 GLN A O 1 ATOM 1556 C CB . GLN A 1 217 ? 41.456 44.081 -3.157 1.00 10.14 ? 217 GLN A CB 1 ATOM 1557 C CG . GLN A 1 217 ? 41.452 42.532 -3.244 1.00 14.09 ? 217 GLN A CG 1 ATOM 1558 C CD . GLN A 1 217 ? 42.247 42.034 -4.418 1.00 14.92 ? 217 GLN A CD 1 ATOM 1559 O OE1 . GLN A 1 217 ? 42.319 42.711 -5.436 1.00 16.97 ? 217 GLN A OE1 1 ATOM 1560 N NE2 . GLN A 1 217 ? 42.848 40.853 -4.294 1.00 15.82 ? 217 GLN A NE2 1 ATOM 1561 N N . LYS A 1 218 ? 44.446 45.465 -3.846 1.00 9.16 ? 218 LYS A N 1 ATOM 1562 C CA . LYS A 1 218 ? 45.750 45.337 -4.536 1.00 9.25 ? 218 LYS A CA 1 ATOM 1563 C C . LYS A 1 218 ? 46.876 45.985 -3.693 1.00 9.77 ? 218 LYS A C 1 ATOM 1564 O O . LYS A 1 218 ? 48.019 46.169 -4.159 1.00 9.11 ? 218 LYS A O 1 ATOM 1565 C CB . LYS A 1 218 ? 45.681 46.023 -5.910 1.00 8.69 ? 218 LYS A CB 1 ATOM 1566 C CG . LYS A 1 218 ? 44.818 45.249 -6.975 1.00 11.27 ? 218 LYS A CG 1 ATOM 1567 C CD . LYS A 1 218 ? 44.660 46.108 -8.269 1.00 10.82 ? 218 LYS A CD 1 ATOM 1568 C CE . LYS A 1 218 ? 44.175 45.304 -9.454 1.00 12.12 ? 218 LYS A CE 1 ATOM 1569 N NZ . LYS A 1 218 ? 43.109 44.296 -9.174 1.00 11.62 ? 218 LYS A NZ 1 ATOM 1570 N N . SER A 1 219 ? 46.515 46.338 -2.458 1.00 8.72 ? 219 SER A N 1 ATOM 1571 C CA . SER A 1 219 ? 47.420 46.957 -1.514 1.00 8.80 ? 219 SER A CA 1 ATOM 1572 C C . SER A 1 219 ? 47.441 46.176 -0.194 1.00 9.29 ? 219 SER A C 1 ATOM 1573 O O . SER A 1 219 ? 47.763 46.709 0.874 1.00 7.74 ? 219 SER A O 1 ATOM 1574 C CB . SER A 1 219 ? 47.011 48.414 -1.280 1.00 8.74 ? 219 SER A CB 1 ATOM 1575 O OG . SER A 1 219 ? 47.157 49.168 -2.470 1.00 8.39 ? 219 SER A OG 1 ATOM 1576 N N . GLY A 1 220 ? 47.096 44.893 -0.283 1.00 9.12 ? 220 GLY A N 1 ATOM 1577 C CA . GLY A 1 220 ? 47.142 44.032 0.885 1.00 7.91 ? 220 GLY A CA 1 ATOM 1578 C C . GLY A 1 220 ? 45.937 44.000 1.804 1.00 9.53 ? 220 GLY A C 1 ATOM 1579 O O . GLY A 1 220 ? 45.942 43.219 2.746 1.00 9.26 ? 220 GLY A O 1 ATOM 1580 N N . PHE A 1 221 ? 44.902 44.792 1.541 1.00 8.35 ? 221 PHE A N 1 ATOM 1581 C CA . PHE A 1 221 ? 43.773 44.819 2.462 1.00 9.40 ? 221 PHE A CA 1 ATOM 1582 C C . PHE A 1 221 ? 42.938 43.572 2.404 1.00 9.22 ? 221 PHE A C 1 ATOM 1583 O O . PHE A 1 221 ? 42.876 42.925 1.375 1.00 9.05 ? 221 PHE A O 1 ATOM 1584 C CB . PHE A 1 221 ? 42.887 46.048 2.206 1.00 7.80 ? 221 PHE A CB 1 ATOM 1585 C CG . PHE A 1 221 ? 43.465 47.328 2.758 1.00 8.92 ? 221 PHE A CG 1 ATOM 1586 C CD1 . PHE A 1 221 ? 44.572 47.932 2.158 1.00 7.50 ? 221 PHE A CD1 1 ATOM 1587 C CD2 . PHE A 1 221 ? 42.911 47.923 3.882 1.00 8.21 ? 221 PHE A CD2 1 ATOM 1588 C CE1 . PHE A 1 221 ? 45.113 49.115 2.688 1.00 9.48 ? 221 PHE A CE1 1 ATOM 1589 C CE2 . PHE A 1 221 ? 43.449 49.100 4.409 1.00 8.28 ? 221 PHE A CE2 1 ATOM 1590 C CZ . PHE A 1 221 ? 44.544 49.699 3.825 1.00 7.55 ? 221 PHE A CZ 1 ATOM 1591 N N . LYS A 1 222 ? 42.304 43.249 3.526 1.00 10.62 ? 222 LYS A N 1 ATOM 1592 C CA . LYS A 1 222 ? 41.443 42.086 3.654 1.00 11.94 ? 222 LYS A CA 1 ATOM 1593 C C . LYS A 1 222 ? 40.012 42.474 4.013 1.00 11.92 ? 222 LYS A C 1 ATOM 1594 O O . LYS A 1 222 ? 39.089 41.676 3.853 1.00 11.90 ? 222 LYS A O 1 ATOM 1595 C CB . LYS A 1 222 ? 42.012 41.161 4.728 1.00 15.68 ? 222 LYS A CB 1 ATOM 1596 C CG . LYS A 1 222 ? 43.042 40.147 4.216 1.00 20.07 ? 222 LYS A CG 1 ATOM 1597 C CD . LYS A 1 222 ? 43.799 40.610 2.976 1.00 26.35 ? 222 LYS A CD 1 ATOM 1598 C CE . LYS A 1 222 ? 44.649 39.492 2.342 1.00 28.72 ? 222 LYS A CE 1 ATOM 1599 N NZ . LYS A 1 222 ? 45.422 38.768 3.376 1.00 31.73 ? 222 LYS A NZ 1 ATOM 1600 N N . ASN A 1 223 ? 39.822 43.700 4.497 1.00 10.31 ? 223 ASN A N 1 ATOM 1601 C CA . ASN A 1 223 ? 38.502 44.148 4.904 1.00 9.97 ? 223 ASN A CA 1 ATOM 1602 C C . ASN A 1 223 ? 38.329 45.669 4.782 1.00 9.13 ? 223 ASN A C 1 ATOM 1603 O O . ASN A 1 223 ? 39.310 46.403 4.850 1.00 8.37 ? 223 ASN A O 1 ATOM 1604 C CB . ASN A 1 223 ? 38.257 43.786 6.385 1.00 9.28 ? 223 ASN A CB 1 ATOM 1605 C CG . ASN A 1 223 ? 38.344 42.302 6.652 1.00 12.11 ? 223 ASN A CG 1 ATOM 1606 O OD1 . ASN A 1 223 ? 39.390 41.785 7.112 1.00 14.20 ? 223 ASN A OD1 1 ATOM 1607 N ND2 . ASN A 1 223 ? 37.265 41.600 6.359 1.00 7.77 ? 223 ASN A ND2 1 ATOM 1608 N N . MET A 1 224 ? 37.079 46.123 4.661 1.00 9.06 ? 224 MET A N 1 ATOM 1609 C CA . MET A 1 224 ? 36.774 47.569 4.615 1.00 9.32 ? 224 MET A CA 1 ATOM 1610 C C . MET A 1 224 ? 35.367 47.826 5.165 1.00 10.24 ? 224 MET A C 1 ATOM 1611 O O . MET A 1 224 ? 34.515 46.932 5.164 1.00 9.48 ? 224 MET A O 1 ATOM 1612 C CB . MET A 1 224 ? 36.861 48.144 3.198 1.00 9.78 ? 224 MET A CB 1 ATOM 1613 C CG . MET A 1 224 ? 35.852 47.583 2.227 1.00 9.50 ? 224 MET A CG 1 ATOM 1614 S SD . MET A 1 224 ? 36.040 48.400 0.621 1.00 11.50 ? 224 MET A SD 1 ATOM 1615 C CE . MET A 1 224 ? 35.514 49.997 0.995 1.00 10.02 ? 224 MET A CE 1 ATOM 1616 N N . LEU A 1 225 ? 35.165 49.053 5.645 1.00 7.92 ? 225 LEU A N 1 ATOM 1617 C CA . LEU A 1 225 ? 33.924 49.474 6.236 1.00 7.79 ? 225 LEU A CA 1 ATOM 1618 C C . LEU A 1 225 ? 33.511 50.801 5.628 1.00 8.26 ? 225 LEU A C 1 ATOM 1619 O O . LEU A 1 225 ? 34.347 51.675 5.437 1.00 9.27 ? 225 LEU A O 1 ATOM 1620 C CB . LEU A 1 225 ? 34.099 49.617 7.752 1.00 6.79 ? 225 LEU A CB 1 ATOM 1621 C CG . LEU A 1 225 ? 32.873 50.198 8.480 1.00 8.10 ? 225 LEU A CG 1 ATOM 1622 C CD1 . LEU A 1 225 ? 32.751 49.569 9.891 1.00 6.55 ? 225 LEU A CD1 1 ATOM 1623 C CD2 . LEU A 1 225 ? 32.997 51.756 8.554 1.00 7.04 ? 225 LEU A CD2 1 ATOM 1624 N N . ILE A 1 226 ? 32.224 50.929 5.310 1.00 9.40 ? 226 ILE A N 1 ATOM 1625 C CA . ILE A 1 226 ? 31.678 52.156 4.717 1.00 10.15 ? 226 ILE A CA 1 ATOM 1626 C C . ILE A 1 226 ? 30.420 52.577 5.489 1.00 10.70 ? 226 ILE A C 1 ATOM 1627 O O . ILE A 1 226 ? 29.815 51.761 6.197 1.00 11.25 ? 226 ILE A O 1 ATOM 1628 C CB . ILE A 1 226 ? 31.362 51.959 3.199 1.00 10.88 ? 226 ILE A CB 1 ATOM 1629 C CG1 . ILE A 1 226 ? 30.303 50.877 2.993 1.00 11.71 ? 226 ILE A CG1 1 ATOM 1630 C CG2 . ILE A 1 226 ? 32.659 51.555 2.428 1.00 10.58 ? 226 ILE A CG2 1 ATOM 1631 C CD1 . ILE A 1 226 ? 29.876 50.741 1.506 1.00 10.70 ? 226 ILE A CD1 1 ATOM 1632 N N . GLN A 1 227 ? 30.039 53.842 5.386 1.00 9.52 ? 227 GLN A N 1 ATOM 1633 C CA . GLN A 1 227 ? 28.884 54.308 6.130 1.00 9.73 ? 227 GLN A CA 1 ATOM 1634 C C . GLN A 1 227 ? 27.871 55.154 5.358 1.00 10.67 ? 227 GLN A C 1 ATOM 1635 O O . GLN A 1 227 ? 26.680 54.818 5.367 1.00 9.26 ? 227 GLN A O 1 ATOM 1636 C CB . GLN A 1 227 ? 29.355 55.073 7.373 1.00 9.30 ? 227 GLN A CB 1 ATOM 1637 C CG . GLN A 1 227 ? 28.421 56.231 7.838 1.00 10.99 ? 227 GLN A CG 1 ATOM 1638 C CD . GLN A 1 227 ? 27.035 55.752 8.345 1.00 10.93 ? 227 GLN A CD 1 ATOM 1639 O OE1 . GLN A 1 227 ? 26.831 54.564 8.633 1.00 9.57 ? 227 GLN A OE1 1 ATOM 1640 N NE2 . GLN A 1 227 ? 26.097 56.686 8.472 1.00 10.31 ? 227 GLN A NE2 1 ATOM 1641 N N . ARG A 1 228 ? 28.306 56.217 4.666 1.00 8.27 ? 228 ARG A N 1 ATOM 1642 C CA . ARG A 1 228 ? 27.310 57.051 3.995 1.00 9.16 ? 228 ARG A CA 1 ATOM 1643 C C . ARG A 1 228 ? 26.754 56.500 2.689 1.00 9.22 ? 228 ARG A C 1 ATOM 1644 O O . ARG A 1 228 ? 27.308 56.740 1.623 1.00 8.40 ? 228 ARG A O 1 ATOM 1645 C CB . ARG A 1 228 ? 27.856 58.470 3.758 1.00 8.31 ? 228 ARG A CB 1 ATOM 1646 C CG . ARG A 1 228 ? 28.032 59.295 5.025 1.00 9.63 ? 228 ARG A CG 1 ATOM 1647 C CD . ARG A 1 228 ? 28.373 60.759 4.634 1.00 11.55 ? 228 ARG A CD 1 ATOM 1648 N NE . ARG A 1 228 ? 28.568 61.684 5.760 1.00 11.87 ? 228 ARG A NE 1 ATOM 1649 C CZ . ARG A 1 228 ? 27.591 62.308 6.421 1.00 13.62 ? 228 ARG A CZ 1 ATOM 1650 N NH1 . ARG A 1 228 ? 26.306 62.106 6.107 1.00 13.15 ? 228 ARG A NH1 1 ATOM 1651 N NH2 . ARG A 1 228 ? 27.910 63.196 7.351 1.00 11.39 ? 228 ARG A NH2 1 ATOM 1652 N N . THR A 1 229 ? 25.686 55.721 2.781 1.00 9.91 ? 229 THR A N 1 ATOM 1653 C CA . THR A 1 229 ? 25.040 55.165 1.596 1.00 9.54 ? 229 THR A CA 1 ATOM 1654 C C . THR A 1 229 ? 23.564 55.539 1.742 1.00 9.81 ? 229 THR A C 1 ATOM 1655 O O . THR A 1 229 ? 23.073 55.795 2.866 1.00 11.81 ? 229 THR A O 1 ATOM 1656 C CB . THR A 1 229 ? 25.225 53.609 1.503 1.00 11.46 ? 229 THR A CB 1 ATOM 1657 O OG1 . THR A 1 229 ? 24.558 52.952 2.600 1.00 11.71 ? 229 THR A OG1 1 ATOM 1658 C CG2 . THR A 1 229 ? 26.705 53.265 1.550 1.00 9.89 ? 229 THR A CG2 1 ATOM 1659 N N . HIS A 1 230 ? 22.853 55.578 0.617 1.00 9.19 ? 230 HIS A N 1 ATOM 1660 C CA . HIS A 1 230 ? 21.443 55.992 0.582 1.00 9.04 ? 230 HIS A CA 1 ATOM 1661 C C . HIS A 1 230 ? 20.578 55.275 1.627 1.00 9.15 ? 230 HIS A C 1 ATOM 1662 O O . HIS A 1 230 ? 20.675 54.069 1.751 1.00 9.06 ? 230 HIS A O 1 ATOM 1663 C CB . HIS A 1 230 ? 20.906 55.739 -0.837 1.00 10.57 ? 230 HIS A CB 1 ATOM 1664 C CG . HIS A 1 230 ? 19.618 56.448 -1.141 1.00 11.37 ? 230 HIS A CG 1 ATOM 1665 N ND1 . HIS A 1 230 ? 18.443 56.185 -0.466 1.00 10.99 ? 230 HIS A ND1 1 ATOM 1666 C CD2 . HIS A 1 230 ? 19.325 57.410 -2.054 1.00 11.84 ? 230 HIS A CD2 1 ATOM 1667 C CE1 . HIS A 1 230 ? 17.481 56.958 -0.945 1.00 11.36 ? 230 HIS A CE1 1 ATOM 1668 N NE2 . HIS A 1 230 ? 17.988 57.710 -1.913 1.00 11.02 ? 230 HIS A NE2 1 ATOM 1669 N N . TYR A 1 231 ? 19.751 56.004 2.387 1.00 9.58 ? 231 TYR A N 1 ATOM 1670 C CA . TYR A 1 231 ? 18.928 55.353 3.406 1.00 11.04 ? 231 TYR A CA 1 ATOM 1671 C C . TYR A 1 231 ? 18.069 54.215 2.869 1.00 11.79 ? 231 TYR A C 1 ATOM 1672 O O . TYR A 1 231 ? 17.799 53.267 3.599 1.00 13.60 ? 231 TYR A O 1 ATOM 1673 C CB . TYR A 1 231 ? 18.040 56.352 4.172 1.00 11.27 ? 231 TYR A CB 1 ATOM 1674 C CG . TYR A 1 231 ? 17.089 57.153 3.302 1.00 13.76 ? 231 TYR A CG 1 ATOM 1675 C CD1 . TYR A 1 231 ? 15.793 56.697 3.045 1.00 12.59 ? 231 TYR A CD1 1 ATOM 1676 C CD2 . TYR A 1 231 ? 17.492 58.381 2.739 1.00 13.51 ? 231 TYR A CD2 1 ATOM 1677 C CE1 . TYR A 1 231 ? 14.922 57.442 2.252 1.00 14.47 ? 231 TYR A CE1 1 ATOM 1678 C CE2 . TYR A 1 231 ? 16.617 59.135 1.943 1.00 13.59 ? 231 TYR A CE2 1 ATOM 1679 C CZ . TYR A 1 231 ? 15.337 58.656 1.704 1.00 14.18 ? 231 TYR A CZ 1 ATOM 1680 O OH . TYR A 1 231 ? 14.466 59.380 0.905 1.00 14.66 ? 231 TYR A OH 1 ATOM 1681 N N . SER A 1 232 ? 17.633 54.299 1.611 1.00 12.14 ? 232 SER A N 1 ATOM 1682 C CA . SER A 1 232 ? 16.823 53.222 1.036 1.00 12.31 ? 232 SER A CA 1 ATOM 1683 C C . SER A 1 232 ? 17.668 51.976 0.827 1.00 11.94 ? 232 SER A C 1 ATOM 1684 O O . SER A 1 232 ? 17.169 50.864 1.001 1.00 11.16 ? 232 SER A O 1 ATOM 1685 C CB . SER A 1 232 ? 16.228 53.645 -0.312 1.00 12.60 ? 232 SER A CB 1 ATOM 1686 O OG . SER A 1 232 ? 15.295 54.690 -0.116 1.00 15.79 ? 232 SER A OG 1 ATOM 1687 N N . VAL A 1 233 ? 18.938 52.167 0.436 1.00 10.04 ? 233 VAL A N 1 ATOM 1688 C CA . VAL A 1 233 ? 19.846 51.055 0.224 1.00 9.77 ? 233 VAL A CA 1 ATOM 1689 C C . VAL A 1 233 ? 20.129 50.339 1.563 1.00 10.82 ? 233 VAL A C 1 ATOM 1690 O O . VAL A 1 233 ? 20.094 49.108 1.652 1.00 10.09 ? 233 VAL A O 1 ATOM 1691 C CB . VAL A 1 233 ? 21.173 51.529 -0.438 1.00 9.03 ? 233 VAL A CB 1 ATOM 1692 C CG1 . VAL A 1 233 ? 22.191 50.365 -0.457 1.00 7.77 ? 233 VAL A CG1 1 ATOM 1693 C CG2 . VAL A 1 233 ? 20.903 51.971 -1.899 1.00 9.88 ? 233 VAL A CG2 1 ATOM 1694 N N . LYS A 1 234 ? 20.397 51.113 2.602 1.00 10.88 ? 234 LYS A N 1 ATOM 1695 C CA . LYS A 1 234 ? 20.614 50.547 3.924 1.00 11.54 ? 234 LYS A CA 1 ATOM 1696 C C . LYS A 1 234 ? 19.405 49.669 4.306 1.00 12.63 ? 234 LYS A C 1 ATOM 1697 O O . LYS A 1 234 ? 19.561 48.517 4.713 1.00 12.49 ? 234 LYS A O 1 ATOM 1698 C CB . LYS A 1 234 ? 20.783 51.684 4.956 1.00 11.03 ? 234 LYS A CB 1 ATOM 1699 C CG . LYS A 1 234 ? 22.167 52.394 4.869 1.00 12.49 ? 234 LYS A CG 1 ATOM 1700 C CD . LYS A 1 234 ? 22.253 53.603 5.796 1.00 9.71 ? 234 LYS A CD 1 ATOM 1701 C CE . LYS A 1 234 ? 23.664 54.250 5.716 1.00 11.71 ? 234 LYS A CE 1 ATOM 1702 N NZ . LYS A 1 234 ? 24.625 53.677 6.736 1.00 11.73 ? 234 LYS A NZ 1 ATOM 1703 N N . LYS A 1 235 ? 18.199 50.221 4.181 1.00 14.14 ? 235 LYS A N 1 ATOM 1704 C CA . LYS A 1 235 ? 16.986 49.475 4.529 1.00 14.47 ? 235 LYS A CA 1 ATOM 1705 C C . LYS A 1 235 ? 16.883 48.180 3.755 1.00 15.21 ? 235 LYS A C 1 ATOM 1706 O O . LYS A 1 235 ? 16.685 47.107 4.330 1.00 15.13 ? 235 LYS A O 1 ATOM 1707 C CB . LYS A 1 235 ? 15.752 50.321 4.261 1.00 15.95 ? 235 LYS A CB 1 ATOM 1708 C CG . LYS A 1 235 ? 14.452 49.701 4.798 1.00 17.48 ? 235 LYS A CG 1 ATOM 1709 C CD . LYS A 1 235 ? 13.295 50.601 4.483 1.00 17.12 ? 235 LYS A CD 1 ATOM 1710 C CE . LYS A 1 235 ? 12.012 49.981 4.974 1.00 20.68 ? 235 LYS A CE 1 ATOM 1711 N NZ . LYS A 1 235 ? 10.887 50.957 4.812 1.00 22.70 ? 235 LYS A NZ 1 ATOM 1712 N N . GLU A 1 236 ? 17.031 48.277 2.440 1.00 15.63 ? 236 GLU A N 1 ATOM 1713 C CA . GLU A 1 236 ? 16.957 47.108 1.569 1.00 15.57 ? 236 GLU A CA 1 ATOM 1714 C C . GLU A 1 236 ? 17.986 46.015 1.931 1.00 15.43 ? 236 GLU A C 1 ATOM 1715 O O . GLU A 1 236 ? 17.637 44.837 2.118 1.00 15.55 ? 236 GLU A O 1 ATOM 1716 C CB . GLU A 1 236 ? 17.172 47.562 0.130 1.00 18.02 ? 236 GLU A CB 1 ATOM 1717 C CG . GLU A 1 236 ? 16.947 46.487 -0.851 1.00 23.29 ? 236 GLU A CG 1 ATOM 1718 C CD . GLU A 1 236 ? 15.465 46.134 -0.995 1.00 25.67 ? 236 GLU A CD 1 ATOM 1719 O OE1 . GLU A 1 236 ? 15.207 45.131 -1.678 1.00 28.62 ? 236 GLU A OE1 1 ATOM 1720 O OE2 . GLU A 1 236 ? 14.574 46.852 -0.450 1.00 27.12 ? 236 GLU A OE2 1 ATOM 1721 N N . LEU A 1 237 ? 19.265 46.381 2.022 1.00 13.47 ? 237 LEU A N 1 ATOM 1722 C CA . LEU A 1 237 ? 20.267 45.383 2.361 1.00 13.07 ? 237 LEU A CA 1 ATOM 1723 C C . LEU A 1 237 ? 20.065 44.848 3.791 1.00 13.21 ? 237 LEU A C 1 ATOM 1724 O O . LEU A 1 237 ? 20.326 43.670 4.080 1.00 13.53 ? 237 LEU A O 1 ATOM 1725 C CB . LEU A 1 237 ? 21.665 45.975 2.220 1.00 10.38 ? 237 LEU A CB 1 ATOM 1726 C CG . LEU A 1 237 ? 22.027 46.418 0.807 1.00 11.40 ? 237 LEU A CG 1 ATOM 1727 C CD1 . LEU A 1 237 ? 23.452 47.004 0.833 1.00 12.07 ? 237 LEU A CD1 1 ATOM 1728 C CD2 . LEU A 1 237 ? 21.995 45.227 -0.160 1.00 10.90 ? 237 LEU A CD2 1 ATOM 1729 N N . ALA A 1 238 ? 19.617 45.710 4.691 1.00 12.73 ? 238 ALA A N 1 ATOM 1730 C CA . ALA A 1 238 ? 19.373 45.262 6.056 1.00 14.28 ? 238 ALA A CA 1 ATOM 1731 C C . ALA A 1 238 ? 18.336 44.133 6.083 1.00 16.17 ? 238 ALA A C 1 ATOM 1732 O O . ALA A 1 238 ? 18.519 43.121 6.766 1.00 15.85 ? 238 ALA A O 1 ATOM 1733 C CB . ALA A 1 238 ? 18.882 46.423 6.911 1.00 12.86 ? 238 ALA A CB 1 ATOM 1734 N N . GLN A 1 239 ? 17.252 44.299 5.334 1.00 16.43 ? 239 GLN A N 1 ATOM 1735 C CA . GLN A 1 239 ? 16.198 43.292 5.361 1.00 18.33 ? 239 GLN A CA 1 ATOM 1736 C C . GLN A 1 239 ? 16.690 41.935 4.865 1.00 18.43 ? 239 GLN A C 1 ATOM 1737 O O . GLN A 1 239 ? 16.177 40.914 5.271 1.00 18.57 ? 239 GLN A O 1 ATOM 1738 C CB . GLN A 1 239 ? 14.992 43.770 4.542 1.00 18.70 ? 239 GLN A CB 1 ATOM 1739 C CG . GLN A 1 239 ? 14.335 45.003 5.159 1.00 22.93 ? 239 GLN A CG 1 ATOM 1740 C CD . GLN A 1 239 ? 13.284 45.669 4.261 1.00 26.45 ? 239 GLN A CD 1 ATOM 1741 O OE1 . GLN A 1 239 ? 13.457 45.771 3.043 1.00 28.27 ? 239 GLN A OE1 1 ATOM 1742 N NE2 . GLN A 1 239 ? 12.206 46.157 4.871 1.00 27.99 ? 239 GLN A NE2 1 ATOM 1743 N N . GLN A 1 240 ? 17.686 41.938 3.989 1.00 17.79 ? 240 GLN A N 1 ATOM 1744 C CA . GLN A 1 240 ? 18.222 40.700 3.439 1.00 17.90 ? 240 GLN A CA 1 ATOM 1745 C C . GLN A 1 240 ? 19.522 40.285 4.132 1.00 17.19 ? 240 GLN A C 1 ATOM 1746 O O . GLN A 1 240 ? 20.158 39.297 3.738 1.00 15.44 ? 240 GLN A O 1 ATOM 1747 C CB . GLN A 1 240 ? 18.498 40.913 1.955 1.00 20.13 ? 240 GLN A CB 1 ATOM 1748 C CG . GLN A 1 240 ? 17.311 41.517 1.196 1.00 22.67 ? 240 GLN A CG 1 ATOM 1749 C CD . GLN A 1 240 ? 16.107 40.605 1.275 1.00 24.24 ? 240 GLN A CD 1 ATOM 1750 O OE1 . GLN A 1 240 ? 16.252 39.388 1.227 1.00 25.67 ? 240 GLN A OE1 1 ATOM 1751 N NE2 . GLN A 1 240 ? 14.914 41.183 1.391 1.00 28.08 ? 240 GLN A NE2 1 ATOM 1752 N N . ARG A 1 241 ? 19.900 41.032 5.173 1.00 15.74 ? 241 ARG A N 1 ATOM 1753 C CA . ARG A 1 241 ? 21.153 40.781 5.876 1.00 14.68 ? 241 ARG A CA 1 ATOM 1754 C C . ARG A 1 241 ? 22.283 40.743 4.836 1.00 14.02 ? 241 ARG A C 1 ATOM 1755 O O . ARG A 1 241 ? 23.111 39.821 4.795 1.00 11.85 ? 241 ARG A O 1 ATOM 1756 C CB . ARG A 1 241 ? 21.077 39.474 6.677 1.00 16.96 ? 241 ARG A CB 1 ATOM 1757 C CG . ARG A 1 241 ? 20.012 39.557 7.810 1.00 19.71 ? 241 ARG A CG 1 ATOM 1758 C CD . ARG A 1 241 ? 20.122 38.428 8.814 1.00 21.89 ? 241 ARG A CD 1 ATOM 1759 N NE . ARG A 1 241 ? 20.245 37.145 8.130 1.00 24.68 ? 241 ARG A NE 1 ATOM 1760 C CZ . ARG A 1 241 ? 20.580 36.001 8.736 1.00 26.97 ? 241 ARG A CZ 1 ATOM 1761 N NH1 . ARG A 1 241 ? 20.817 35.993 10.053 1.00 26.61 ? 241 ARG A NH1 1 ATOM 1762 N NH2 . ARG A 1 241 ? 20.719 34.874 8.027 1.00 25.26 ? 241 ARG A NH2 1 ATOM 1763 N N . GLN A 1 242 ? 22.301 41.753 3.957 1.00 13.73 ? 242 GLN A N 1 ATOM 1764 C CA . GLN A 1 242 ? 23.369 41.830 2.952 1.00 11.90 ? 242 GLN A CA 1 ATOM 1765 C C . GLN A 1 242 ? 24.190 43.106 3.198 1.00 12.84 ? 242 GLN A C 1 ATOM 1766 O O . GLN A 1 242 ? 24.685 43.715 2.238 1.00 11.16 ? 242 GLN A O 1 ATOM 1767 C CB . GLN A 1 242 ? 22.774 41.832 1.530 1.00 13.11 ? 242 GLN A CB 1 ATOM 1768 C CG . GLN A 1 242 ? 21.997 40.529 1.163 1.00 12.12 ? 242 GLN A CG 1 ATOM 1769 C CD . GLN A 1 242 ? 21.195 40.669 -0.127 1.00 13.58 ? 242 GLN A CD 1 ATOM 1770 O OE1 . GLN A 1 242 ? 20.648 41.728 -0.401 1.00 14.84 ? 242 GLN A OE1 1 ATOM 1771 N NE2 . GLN A 1 242 ? 21.113 39.589 -0.912 1.00 13.16 ? 242 GLN A NE2 1 ATOM 1772 N N . LEU A 1 243 ? 24.317 43.516 4.474 1.00 10.59 ? 243 LEU A N 1 ATOM 1773 C CA . LEU A 1 243 ? 25.100 44.705 4.824 1.00 11.54 ? 243 LEU A CA 1 ATOM 1774 C C . LEU A 1 243 ? 26.578 44.374 4.829 1.00 11.78 ? 243 LEU A C 1 ATOM 1775 O O . LEU A 1 243 ? 27.427 45.271 4.828 1.00 12.49 ? 243 LEU A O 1 ATOM 1776 C CB . LEU A 1 243 ? 24.674 45.270 6.194 1.00 9.86 ? 243 LEU A CB 1 ATOM 1777 C CG . LEU A 1 243 ? 23.299 45.960 6.148 1.00 10.54 ? 243 LEU A CG 1 ATOM 1778 C CD1 . LEU A 1 243 ? 22.770 46.213 7.590 1.00 8.70 ? 243 LEU A CD1 1 ATOM 1779 C CD2 . LEU A 1 243 ? 23.399 47.274 5.340 1.00 8.35 ? 243 LEU A CD2 1 ATOM 1780 N N . GLU A 1 244 ? 26.886 43.078 4.879 1.00 11.77 ? 244 GLU A N 1 ATOM 1781 C CA . GLU A 1 244 ? 28.263 42.622 4.790 1.00 11.43 ? 244 GLU A CA 1 ATOM 1782 C C . GLU A 1 244 ? 28.323 41.834 3.502 1.00 11.59 ? 244 GLU A C 1 ATOM 1783 O O . GLU A 1 244 ? 27.501 40.949 3.282 1.00 11.98 ? 244 GLU A O 1 ATOM 1784 C CB . GLU A 1 244 ? 28.657 41.771 6.018 1.00 10.79 ? 244 GLU A CB 1 ATOM 1785 C CG . GLU A 1 244 ? 28.976 42.689 7.216 1.00 9.23 ? 244 GLU A CG 1 ATOM 1786 C CD . GLU A 1 244 ? 29.346 41.964 8.490 1.00 10.19 ? 244 GLU A CD 1 ATOM 1787 O OE1 . GLU A 1 244 ? 28.789 40.880 8.741 1.00 9.17 ? 244 GLU A OE1 1 ATOM 1788 O OE2 . GLU A 1 244 ? 30.189 42.507 9.245 1.00 10.66 ? 244 GLU A OE2 1 ATOM 1789 N N . PHE A 1 245 ? 29.287 42.156 2.640 1.00 11.53 ? 245 PHE A N 1 ATOM 1790 C CA . PHE A 1 245 ? 29.366 41.493 1.342 1.00 11.09 ? 245 PHE A CA 1 ATOM 1791 C C . PHE A 1 245 ? 30.775 41.492 0.769 1.00 10.23 ? 245 PHE A C 1 ATOM 1792 O O . PHE A 1 245 ? 31.651 42.200 1.264 1.00 9.68 ? 245 PHE A O 1 ATOM 1793 C CB . PHE A 1 245 ? 28.394 42.203 0.362 1.00 9.26 ? 245 PHE A CB 1 ATOM 1794 C CG . PHE A 1 245 ? 28.519 43.719 0.370 1.00 10.76 ? 245 PHE A CG 1 ATOM 1795 C CD1 . PHE A 1 245 ? 29.435 44.367 -0.460 1.00 10.02 ? 245 PHE A CD1 1 ATOM 1796 C CD2 . PHE A 1 245 ? 27.733 44.499 1.242 1.00 11.30 ? 245 PHE A CD2 1 ATOM 1797 C CE1 . PHE A 1 245 ? 29.573 45.786 -0.430 1.00 10.35 ? 245 PHE A CE1 1 ATOM 1798 C CE2 . PHE A 1 245 ? 27.858 45.900 1.284 1.00 9.35 ? 245 PHE A CE2 1 ATOM 1799 C CZ . PHE A 1 245 ? 28.781 46.540 0.442 1.00 9.37 ? 245 PHE A CZ 1 ATOM 1800 N N . LEU A 1 246 ? 30.976 40.687 -0.275 1.00 9.43 ? 246 LEU A N 1 ATOM 1801 C CA . LEU A 1 246 ? 32.248 40.577 -0.962 1.00 9.08 ? 246 LEU A CA 1 ATOM 1802 C C . LEU A 1 246 ? 32.069 41.466 -2.186 1.00 9.68 ? 246 LEU A C 1 ATOM 1803 O O . LEU A 1 246 ? 31.422 41.097 -3.177 1.00 9.76 ? 246 LEU A O 1 ATOM 1804 C CB . LEU A 1 246 ? 32.508 39.109 -1.344 1.00 11.07 ? 246 LEU A CB 1 ATOM 1805 C CG . LEU A 1 246 ? 32.711 38.194 -0.112 1.00 13.78 ? 246 LEU A CG 1 ATOM 1806 C CD1 . LEU A 1 246 ? 32.730 36.694 -0.483 1.00 14.90 ? 246 LEU A CD1 1 ATOM 1807 C CD2 . LEU A 1 246 ? 34.044 38.557 0.491 1.00 17.37 ? 246 LEU A CD2 1 ATOM 1808 N N . TRP A 1 247 ? 32.620 42.667 -2.088 1.00 9.28 ? 247 TRP A N 1 ATOM 1809 C CA . TRP A 1 247 ? 32.511 43.662 -3.141 1.00 8.56 ? 247 TRP A CA 1 ATOM 1810 C C . TRP A 1 247 ? 33.548 43.443 -4.231 1.00 9.54 ? 247 TRP A C 1 ATOM 1811 O O . TRP A 1 247 ? 34.774 43.613 -3.999 1.00 8.98 ? 247 TRP A O 1 ATOM 1812 C CB . TRP A 1 247 ? 32.686 45.044 -2.505 1.00 10.35 ? 247 TRP A CB 1 ATOM 1813 C CG . TRP A 1 247 ? 32.208 46.232 -3.283 1.00 8.28 ? 247 TRP A CG 1 ATOM 1814 C CD1 . TRP A 1 247 ? 31.626 46.250 -4.524 1.00 8.58 ? 247 TRP A CD1 1 ATOM 1815 C CD2 . TRP A 1 247 ? 32.235 47.592 -2.827 1.00 7.99 ? 247 TRP A CD2 1 ATOM 1816 N NE1 . TRP A 1 247 ? 31.284 47.561 -4.868 1.00 6.09 ? 247 TRP A NE1 1 ATOM 1817 C CE2 . TRP A 1 247 ? 31.649 48.393 -3.843 1.00 7.05 ? 247 TRP A CE2 1 ATOM 1818 C CE3 . TRP A 1 247 ? 32.695 48.211 -1.652 1.00 8.19 ? 247 TRP A CE3 1 ATOM 1819 C CZ2 . TRP A 1 247 ? 31.513 49.786 -3.718 1.00 8.13 ? 247 TRP A CZ2 1 ATOM 1820 C CZ3 . TRP A 1 247 ? 32.556 49.612 -1.530 1.00 6.86 ? 247 TRP A CZ3 1 ATOM 1821 C CH2 . TRP A 1 247 ? 31.973 50.377 -2.553 1.00 6.83 ? 247 TRP A CH2 1 ATOM 1822 N N . ARG A 1 248 ? 33.073 43.057 -5.417 1.00 7.44 ? 248 ARG A N 1 ATOM 1823 C CA . ARG A 1 248 ? 33.976 42.856 -6.540 1.00 8.46 ? 248 ARG A CA 1 ATOM 1824 C C . ARG A 1 248 ? 33.650 43.910 -7.585 1.00 8.53 ? 248 ARG A C 1 ATOM 1825 O O . ARG A 1 248 ? 32.568 44.518 -7.534 1.00 8.25 ? 248 ARG A O 1 ATOM 1826 C CB . ARG A 1 248 ? 33.780 41.467 -7.169 1.00 8.50 ? 248 ARG A CB 1 ATOM 1827 C CG . ARG A 1 248 ? 32.440 41.335 -7.895 1.00 10.16 ? 248 ARG A CG 1 ATOM 1828 C CD . ARG A 1 248 ? 32.396 40.035 -8.716 1.00 11.37 ? 248 ARG A CD 1 ATOM 1829 N NE . ARG A 1 248 ? 32.331 38.858 -7.838 1.00 12.82 ? 248 ARG A NE 1 ATOM 1830 C CZ . ARG A 1 248 ? 32.286 37.601 -8.291 1.00 14.38 ? 248 ARG A CZ 1 ATOM 1831 N NH1 . ARG A 1 248 ? 32.316 37.348 -9.608 1.00 10.70 ? 248 ARG A NH1 1 ATOM 1832 N NH2 . ARG A 1 248 ? 32.167 36.599 -7.428 1.00 13.27 ? 248 ARG A NH2 1 ATOM 1833 N N . GLN A 1 249 ? 34.576 44.108 -8.532 1.00 9.17 ? 249 GLN A N 1 ATOM 1834 C CA . GLN A 1 249 ? 34.416 45.083 -9.599 1.00 10.03 ? 249 GLN A CA 1 ATOM 1835 C C . GLN A 1 249 ? 33.317 44.612 -10.548 1.00 9.76 ? 249 GLN A C 1 ATOM 1836 O O . GLN A 1 249 ? 33.099 43.407 -10.705 1.00 8.75 ? 249 GLN A O 1 ATOM 1837 C CB . GLN A 1 249 ? 35.762 45.273 -10.329 1.00 9.40 ? 249 GLN A CB 1 ATOM 1838 C CG . GLN A 1 249 ? 36.855 45.792 -9.390 1.00 10.04 ? 249 GLN A CG 1 ATOM 1839 C CD . GLN A 1 249 ? 36.420 47.097 -8.692 1.00 10.51 ? 249 GLN A CD 1 ATOM 1840 O OE1 . GLN A 1 249 ? 36.057 48.067 -9.368 1.00 10.29 ? 249 GLN A OE1 1 ATOM 1841 N NE2 . GLN A 1 249 ? 36.446 47.120 -7.342 1.00 8.03 ? 249 GLN A NE2 1 ATOM 1842 N N . ILE A 1 250 ? 32.620 45.560 -11.168 1.00 9.65 ? 250 ILE A N 1 ATOM 1843 C CA . ILE A 1 250 ? 31.485 45.230 -12.044 1.00 9.90 ? 250 ILE A CA 1 ATOM 1844 C C . ILE A 1 250 ? 31.791 44.311 -13.224 1.00 11.31 ? 250 ILE A C 1 ATOM 1845 O O . ILE A 1 250 ? 30.885 43.598 -13.710 1.00 11.87 ? 250 ILE A O 1 ATOM 1846 C CB . ILE A 1 250 ? 30.769 46.513 -12.585 1.00 10.02 ? 250 ILE A CB 1 ATOM 1847 C CG1 . ILE A 1 250 ? 31.774 47.402 -13.331 1.00 9.48 ? 250 ILE A CG1 1 ATOM 1848 C CG2 . ILE A 1 250 ? 30.113 47.278 -11.437 1.00 8.74 ? 250 ILE A CG2 1 ATOM 1849 C CD1 . ILE A 1 250 ? 31.187 48.737 -13.847 1.00 10.34 ? 250 ILE A CD1 1 ATOM 1850 N N . TRP A 1 251 ? 33.040 44.316 -13.685 1.00 11.51 ? 251 TRP A N 1 ATOM 1851 C CA . TRP A 1 251 ? 33.444 43.459 -14.807 1.00 14.37 ? 251 TRP A CA 1 ATOM 1852 C C . TRP A 1 251 ? 34.099 42.136 -14.371 1.00 16.00 ? 251 TRP A C 1 ATOM 1853 O O . TRP A 1 251 ? 34.381 41.277 -15.202 1.00 16.64 ? 251 TRP A O 1 ATOM 1854 C CB . TRP A 1 251 ? 34.468 44.185 -15.666 1.00 14.26 ? 251 TRP A CB 1 ATOM 1855 C CG . TRP A 1 251 ? 35.747 44.343 -14.922 1.00 16.10 ? 251 TRP A CG 1 ATOM 1856 C CD1 . TRP A 1 251 ? 36.721 43.400 -14.738 1.00 16.23 ? 251 TRP A CD1 1 ATOM 1857 C CD2 . TRP A 1 251 ? 36.160 45.492 -14.218 1.00 15.18 ? 251 TRP A CD2 1 ATOM 1858 N NE1 . TRP A 1 251 ? 37.722 43.910 -13.963 1.00 18.06 ? 251 TRP A NE1 1 ATOM 1859 C CE2 . TRP A 1 251 ? 37.398 45.196 -13.624 1.00 16.08 ? 251 TRP A CE2 1 ATOM 1860 C CE3 . TRP A 1 251 ? 35.595 46.754 -14.025 1.00 14.78 ? 251 TRP A CE3 1 ATOM 1861 C CZ2 . TRP A 1 251 ? 38.089 46.110 -12.854 1.00 15.72 ? 251 TRP A CZ2 1 ATOM 1862 C CZ3 . TRP A 1 251 ? 36.272 47.666 -13.263 1.00 16.08 ? 251 TRP A CZ3 1 ATOM 1863 C CH2 . TRP A 1 251 ? 37.511 47.347 -12.684 1.00 16.86 ? 251 TRP A CH2 1 ATOM 1864 N N . ASP A 1 252 ? 34.337 41.987 -13.072 1.00 16.78 ? 252 ASP A N 1 ATOM 1865 C CA . ASP A 1 252 ? 35.022 40.825 -12.505 1.00 17.31 ? 252 ASP A CA 1 ATOM 1866 C C . ASP A 1 252 ? 34.183 39.558 -12.453 1.00 17.95 ? 252 ASP A C 1 ATOM 1867 O O . ASP A 1 252 ? 33.420 39.308 -11.523 1.00 18.24 ? 252 ASP A O 1 ATOM 1868 C CB . ASP A 1 252 ? 35.551 41.182 -11.103 1.00 16.89 ? 252 ASP A CB 1 ATOM 1869 C CG . ASP A 1 252 ? 36.374 40.052 -10.481 1.00 18.33 ? 252 ASP A CG 1 ATOM 1870 O OD1 . ASP A 1 252 ? 36.626 39.035 -11.183 1.00 17.01 ? 252 ASP A OD1 1 ATOM 1871 O OD2 . ASP A 1 252 ? 36.759 40.194 -9.300 1.00 15.83 ? 252 ASP A OD2 1 ATOM 1872 N N . ASN A 1 253 ? 34.340 38.732 -13.470 1.00 19.02 ? 253 ASN A N 1 ATOM 1873 C CA . ASN A 1 253 ? 33.560 37.519 -13.524 1.00 20.49 ? 253 ASN A CA 1 ATOM 1874 C C . ASN A 1 253 ? 34.036 36.447 -12.539 1.00 20.23 ? 253 ASN A C 1 ATOM 1875 O O . ASN A 1 253 ? 33.227 35.730 -11.954 1.00 21.02 ? 253 ASN A O 1 ATOM 1876 C CB . ASN A 1 253 ? 33.583 36.988 -14.954 1.00 23.65 ? 253 ASN A CB 1 ATOM 1877 C CG . ASN A 1 253 ? 32.746 35.763 -15.107 1.00 26.53 ? 253 ASN A CG 1 ATOM 1878 O OD1 . ASN A 1 253 ? 33.270 34.643 -15.172 1.00 28.84 ? 253 ASN A OD1 1 ATOM 1879 N ND2 . ASN A 1 253 ? 31.424 35.951 -15.148 1.00 28.81 ? 253 ASN A ND2 1 ATOM 1880 N N . LYS A 1 254 ? 35.338 36.363 -12.325 1.00 20.37 ? 254 LYS A N 1 ATOM 1881 C CA . LYS A 1 254 ? 35.891 35.346 -11.426 1.00 22.26 ? 254 LYS A CA 1 ATOM 1882 C C . LYS A 1 254 ? 35.746 35.683 -9.936 1.00 21.39 ? 254 LYS A C 1 ATOM 1883 O O . LYS A 1 254 ? 35.495 34.807 -9.110 1.00 20.10 ? 254 LYS A O 1 ATOM 1884 C CB . LYS A 1 254 ? 37.364 35.119 -11.776 1.00 25.50 ? 254 LYS A CB 1 ATOM 1885 C CG . LYS A 1 254 ? 37.919 33.793 -11.245 1.00 29.96 ? 254 LYS A CG 1 ATOM 1886 C CD . LYS A 1 254 ? 39.358 33.548 -11.705 1.00 31.31 ? 254 LYS A CD 1 ATOM 1887 C CE . LYS A 1 254 ? 39.922 32.257 -11.062 1.00 33.05 ? 254 LYS A CE 1 ATOM 1888 N NZ . LYS A 1 254 ? 39.926 32.289 -9.565 1.00 32.62 ? 254 LYS A NZ 1 ATOM 1889 N N . GLY A 1 255 ? 35.911 36.958 -9.602 1.00 20.71 ? 255 GLY A N 1 ATOM 1890 C CA . GLY A 1 255 ? 35.783 37.382 -8.225 1.00 20.25 ? 255 GLY A CA 1 ATOM 1891 C C . GLY A 1 255 ? 37.100 37.608 -7.506 1.00 20.06 ? 255 GLY A C 1 ATOM 1892 O O . GLY A 1 255 ? 37.106 37.769 -6.300 1.00 20.22 ? 255 GLY A O 1 ATOM 1893 N N . ASP A 1 256 ? 38.217 37.626 -8.225 1.00 20.11 ? 256 ASP A N 1 ATOM 1894 C CA . ASP A 1 256 ? 39.498 37.823 -7.561 1.00 21.28 ? 256 ASP A CA 1 ATOM 1895 C C . ASP A 1 256 ? 39.706 39.248 -7.076 1.00 19.14 ? 256 ASP A C 1 ATOM 1896 O O . ASP A 1 256 ? 40.659 39.496 -6.360 1.00 18.83 ? 256 ASP A O 1 ATOM 1897 C CB . ASP A 1 256 ? 40.682 37.476 -8.472 1.00 25.75 ? 256 ASP A CB 1 ATOM 1898 C CG . ASP A 1 256 ? 40.683 36.024 -8.923 1.00 29.82 ? 256 ASP A CG 1 ATOM 1899 O OD1 . ASP A 1 256 ? 40.351 35.124 -8.107 1.00 31.63 ? 256 ASP A OD1 1 ATOM 1900 O OD2 . ASP A 1 256 ? 41.036 35.796 -10.103 1.00 32.89 ? 256 ASP A OD2 1 ATOM 1901 N N . THR A 1 257 ? 38.852 40.189 -7.486 1.00 17.11 ? 257 THR A N 1 ATOM 1902 C CA . THR A 1 257 ? 38.999 41.574 -7.013 1.00 15.20 ? 257 THR A CA 1 ATOM 1903 C C . THR A 1 257 ? 38.219 41.812 -5.695 1.00 14.67 ? 257 THR A C 1 ATOM 1904 O O . THR A 1 257 ? 38.293 42.915 -5.105 1.00 14.01 ? 257 THR A O 1 ATOM 1905 C CB . THR A 1 257 ? 38.460 42.593 -8.052 1.00 14.30 ? 257 THR A CB 1 ATOM 1906 O OG1 . THR A 1 257 ? 37.051 42.372 -8.243 1.00 13.14 ? 257 THR A OG1 1 ATOM 1907 C CG2 . THR A 1 257 ? 39.207 42.437 -9.402 1.00 14.48 ? 257 THR A CG2 1 ATOM 1908 N N . ALA A 1 258 ? 37.494 40.782 -5.250 1.00 12.34 ? 258 ALA A N 1 ATOM 1909 C CA . ALA A 1 258 ? 36.646 40.862 -4.079 1.00 11.80 ? 258 ALA A CA 1 ATOM 1910 C C . ALA A 1 258 ? 37.315 41.284 -2.778 1.00 11.44 ? 258 ALA A C 1 ATOM 1911 O O . ALA A 1 258 ? 38.420 40.850 -2.467 1.00 11.65 ? 258 ALA A O 1 ATOM 1912 C CB . ALA A 1 258 ? 35.924 39.534 -3.874 1.00 11.87 ? 258 ALA A CB 1 ATOM 1913 N N . LEU A 1 259 ? 36.636 42.143 -2.018 1.00 10.77 ? 259 LEU A N 1 ATOM 1914 C CA . LEU A 1 259 ? 37.145 42.602 -0.730 1.00 9.89 ? 259 LEU A CA 1 ATOM 1915 C C . LEU A 1 259 ? 35.951 42.604 0.220 1.00 9.66 ? 259 LEU A C 1 ATOM 1916 O O . LEU A 1 259 ? 34.904 43.212 -0.082 1.00 8.43 ? 259 LEU A O 1 ATOM 1917 C CB . LEU A 1 259 ? 37.719 44.021 -0.843 1.00 8.57 ? 259 LEU A CB 1 ATOM 1918 C CG . LEU A 1 259 ? 38.421 44.478 0.429 1.00 8.84 ? 259 LEU A CG 1 ATOM 1919 C CD1 . LEU A 1 259 ? 39.573 43.511 0.664 1.00 8.75 ? 259 LEU A CD1 1 ATOM 1920 C CD2 . LEU A 1 259 ? 38.882 45.961 0.344 1.00 5.97 ? 259 LEU A CD2 1 ATOM 1921 N N . PHE A 1 260 ? 36.094 41.926 1.356 1.00 9.50 ? 260 PHE A N 1 ATOM 1922 C CA . PHE A 1 260 ? 35.001 41.864 2.332 1.00 8.31 ? 260 PHE A CA 1 ATOM 1923 C C . PHE A 1 260 ? 34.642 43.283 2.778 1.00 8.88 ? 260 PHE A C 1 ATOM 1924 O O . PHE A 1 260 ? 35.525 44.068 3.162 1.00 8.97 ? 260 PHE A O 1 ATOM 1925 C CB . PHE A 1 260 ? 35.408 40.994 3.547 1.00 9.45 ? 260 PHE A CB 1 ATOM 1926 C CG . PHE A 1 260 ? 34.286 40.806 4.547 1.00 10.32 ? 260 PHE A CG 1 ATOM 1927 C CD1 . PHE A 1 260 ? 33.289 39.858 4.314 1.00 10.85 ? 260 PHE A CD1 1 ATOM 1928 C CD2 . PHE A 1 260 ? 34.196 41.605 5.686 1.00 10.04 ? 260 PHE A CD2 1 ATOM 1929 C CE1 . PHE A 1 260 ? 32.235 39.707 5.179 1.00 10.78 ? 260 PHE A CE1 1 ATOM 1930 C CE2 . PHE A 1 260 ? 33.135 41.462 6.573 1.00 10.28 ? 260 PHE A CE2 1 ATOM 1931 C CZ . PHE A 1 260 ? 32.150 40.511 6.319 1.00 12.11 ? 260 PHE A CZ 1 ATOM 1932 N N . THR A 1 261 ? 33.350 43.614 2.751 1.00 8.58 ? 261 THR A N 1 ATOM 1933 C CA . THR A 1 261 ? 32.922 44.946 3.090 1.00 8.35 ? 261 THR A CA 1 ATOM 1934 C C . THR A 1 261 ? 31.778 44.964 4.116 1.00 9.23 ? 261 THR A C 1 ATOM 1935 O O . THR A 1 261 ? 30.814 44.208 4.001 1.00 9.56 ? 261 THR A O 1 ATOM 1936 C CB . THR A 1 261 ? 32.438 45.690 1.829 1.00 8.45 ? 261 THR A CB 1 ATOM 1937 O OG1 . THR A 1 261 ? 33.488 45.715 0.856 1.00 7.78 ? 261 THR A OG1 1 ATOM 1938 C CG2 . THR A 1 261 ? 32.011 47.128 2.166 1.00 6.71 ? 261 THR A CG2 1 ATOM 1939 N N . HIS A 1 262 ? 31.891 45.837 5.114 1.00 8.52 ? 262 HIS A N 1 ATOM 1940 C CA . HIS A 1 262 ? 30.841 45.999 6.120 1.00 8.32 ? 262 HIS A CA 1 ATOM 1941 C C . HIS A 1 262 ? 30.217 47.386 5.950 1.00 9.75 ? 262 HIS A C 1 ATOM 1942 O O . HIS A 1 262 ? 30.907 48.422 6.108 1.00 9.36 ? 262 HIS A O 1 ATOM 1943 C CB . HIS A 1 262 ? 31.443 45.891 7.532 1.00 9.46 ? 262 HIS A CB 1 ATOM 1944 C CG . HIS A 1 262 ? 30.489 46.225 8.641 1.00 9.96 ? 262 HIS A CG 1 ATOM 1945 N ND1 . HIS A 1 262 ? 29.904 45.259 9.433 1.00 10.15 ? 262 HIS A ND1 1 ATOM 1946 C CD2 . HIS A 1 262 ? 30.033 47.415 9.106 1.00 10.07 ? 262 HIS A CD2 1 ATOM 1947 C CE1 . HIS A 1 262 ? 29.131 45.840 10.338 1.00 9.37 ? 262 HIS A CE1 1 ATOM 1948 N NE2 . HIS A 1 262 ? 29.193 47.145 10.165 1.00 9.28 ? 262 HIS A NE2 1 ATOM 1949 N N . MET A 1 263 ? 28.922 47.426 5.624 1.00 9.57 ? 263 MET A N 1 ATOM 1950 C CA . MET A 1 263 ? 28.228 48.696 5.526 1.00 10.92 ? 263 MET A CA 1 ATOM 1951 C C . MET A 1 263 ? 27.522 48.934 6.875 1.00 12.69 ? 263 MET A C 1 ATOM 1952 O O . MET A 1 263 ? 26.761 48.057 7.336 1.00 12.32 ? 263 MET A O 1 ATOM 1953 C CB . MET A 1 263 ? 27.172 48.666 4.413 1.00 11.40 ? 263 MET A CB 1 ATOM 1954 C CG . MET A 1 263 ? 26.431 50.013 4.229 1.00 10.81 ? 263 MET A CG 1 ATOM 1955 S SD . MET A 1 263 ? 25.071 49.883 3.034 1.00 12.96 ? 263 MET A SD 1 ATOM 1956 C CE . MET A 1 263 ? 25.953 49.612 1.485 1.00 11.06 ? 263 MET A CE 1 ATOM 1957 N N . MET A 1 264 ? 27.759 50.080 7.521 1.00 10.00 ? 264 MET A N 1 ATOM 1958 C CA . MET A 1 264 ? 27.066 50.351 8.781 1.00 11.27 ? 264 MET A CA 1 ATOM 1959 C C . MET A 1 264 ? 25.590 50.547 8.371 1.00 11.47 ? 264 MET A C 1 ATOM 1960 O O . MET A 1 264 ? 25.296 51.013 7.265 1.00 11.12 ? 264 MET A O 1 ATOM 1961 C CB . MET A 1 264 ? 27.669 51.567 9.472 1.00 11.18 ? 264 MET A CB 1 ATOM 1962 C CG . MET A 1 264 ? 29.085 51.289 9.984 1.00 12.92 ? 264 MET A CG 1 ATOM 1963 S SD . MET A 1 264 ? 29.962 52.862 10.517 1.00 16.63 ? 264 MET A SD 1 ATOM 1964 C CE . MET A 1 264 ? 28.948 53.486 11.722 1.00 16.51 ? 264 MET A CE 1 ATOM 1965 N N . PRO A 1 265 ? 24.641 50.189 9.256 1.00 12.14 ? 265 PRO A N 1 ATOM 1966 C CA . PRO A 1 265 ? 23.210 50.289 8.935 1.00 11.70 ? 265 PRO A CA 1 ATOM 1967 C C . PRO A 1 265 ? 22.412 51.563 9.145 1.00 13.75 ? 265 PRO A C 1 ATOM 1968 O O . PRO A 1 265 ? 21.335 51.738 8.540 1.00 12.52 ? 265 PRO A O 1 ATOM 1969 C CB . PRO A 1 265 ? 22.615 49.133 9.763 1.00 14.23 ? 265 PRO A CB 1 ATOM 1970 C CG . PRO A 1 265 ? 23.408 49.240 11.052 1.00 14.23 ? 265 PRO A CG 1 ATOM 1971 C CD . PRO A 1 265 ? 24.844 49.656 10.620 1.00 12.18 ? 265 PRO A CD 1 ATOM 1972 N N . PHE A 1 266 ? 22.932 52.465 9.962 1.00 12.42 ? 266 PHE A N 1 ATOM 1973 C CA . PHE A 1 266 ? 22.174 53.639 10.305 1.00 12.57 ? 266 PHE A CA 1 ATOM 1974 C C . PHE A 1 266 ? 22.544 54.981 9.688 1.00 12.21 ? 266 PHE A C 1 ATOM 1975 O O . PHE A 1 266 ? 23.456 55.090 8.865 1.00 12.99 ? 266 PHE A O 1 ATOM 1976 C CB . PHE A 1 266 ? 22.111 53.684 11.839 1.00 12.21 ? 266 PHE A CB 1 ATOM 1977 C CG . PHE A 1 266 ? 21.557 52.385 12.456 1.00 12.20 ? 266 PHE A CG 1 ATOM 1978 C CD1 . PHE A 1 266 ? 22.178 51.782 13.554 1.00 11.86 ? 266 PHE A CD1 1 ATOM 1979 C CD2 . PHE A 1 266 ? 20.419 51.772 11.916 1.00 12.01 ? 266 PHE A CD2 1 ATOM 1980 C CE1 . PHE A 1 266 ? 21.675 50.580 14.112 1.00 13.48 ? 266 PHE A CE1 1 ATOM 1981 C CE2 . PHE A 1 266 ? 19.909 50.592 12.446 1.00 11.45 ? 266 PHE A CE2 1 ATOM 1982 C CZ . PHE A 1 266 ? 20.536 49.975 13.556 1.00 11.79 ? 266 PHE A CZ 1 ATOM 1983 N N . TYR A 1 267 ? 21.807 56.002 10.117 1.00 12.52 ? 267 TYR A N 1 ATOM 1984 C CA . TYR A 1 267 ? 21.905 57.354 9.601 1.00 12.05 ? 267 TYR A CA 1 ATOM 1985 C C . TYR A 1 267 ? 23.236 58.065 9.828 1.00 12.06 ? 267 TYR A C 1 ATOM 1986 O O . TYR A 1 267 ? 23.673 58.872 8.998 1.00 11.91 ? 267 TYR A O 1 ATOM 1987 C CB . TYR A 1 267 ? 20.751 58.169 10.214 1.00 12.67 ? 267 TYR A CB 1 ATOM 1988 C CG . TYR A 1 267 ? 20.870 59.677 10.086 1.00 13.97 ? 267 TYR A CG 1 ATOM 1989 C CD1 . TYR A 1 267 ? 20.567 60.327 8.875 1.00 16.09 ? 267 TYR A CD1 1 ATOM 1990 C CD2 . TYR A 1 267 ? 21.218 60.468 11.195 1.00 14.57 ? 267 TYR A CD2 1 ATOM 1991 C CE1 . TYR A 1 267 ? 20.594 61.745 8.779 1.00 15.26 ? 267 TYR A CE1 1 ATOM 1992 C CE2 . TYR A 1 267 ? 21.256 61.884 11.113 1.00 14.29 ? 267 TYR A CE2 1 ATOM 1993 C CZ . TYR A 1 267 ? 20.938 62.501 9.901 1.00 15.79 ? 267 TYR A CZ 1 ATOM 1994 O OH . TYR A 1 267 ? 20.953 63.874 9.804 1.00 17.24 ? 267 TYR A OH 1 ATOM 1995 N N . SER A 1 268 ? 23.878 57.779 10.953 1.00 11.07 ? 268 SER A N 1 ATOM 1996 C CA . SER A 1 268 ? 25.139 58.433 11.267 1.00 11.26 ? 268 SER A CA 1 ATOM 1997 C C . SER A 1 268 ? 26.089 57.465 11.954 1.00 11.57 ? 268 SER A C 1 ATOM 1998 O O . SER A 1 268 ? 25.689 56.351 12.323 1.00 12.27 ? 268 SER A O 1 ATOM 1999 C CB . SER A 1 268 ? 24.860 59.616 12.191 1.00 10.28 ? 268 SER A CB 1 ATOM 2000 O OG . SER A 1 268 ? 26.050 60.196 12.696 1.00 12.05 ? 268 SER A OG 1 ATOM 2001 N N . TYR A 1 269 ? 27.356 57.870 12.089 1.00 11.66 ? 269 TYR A N 1 ATOM 2002 C CA . TYR A 1 269 ? 28.326 57.055 12.816 1.00 9.91 ? 269 TYR A CA 1 ATOM 2003 C C . TYR A 1 269 ? 28.431 57.606 14.255 1.00 9.84 ? 269 TYR A C 1 ATOM 2004 O O . TYR A 1 269 ? 29.255 57.122 15.045 1.00 10.58 ? 269 TYR A O 1 ATOM 2005 C CB . TYR A 1 269 ? 29.707 57.111 12.162 1.00 9.77 ? 269 TYR A CB 1 ATOM 2006 C CG . TYR A 1 269 ? 30.188 58.510 11.894 1.00 9.80 ? 269 TYR A CG 1 ATOM 2007 C CD1 . TYR A 1 269 ? 30.606 59.354 12.930 1.00 8.21 ? 269 TYR A CD1 1 ATOM 2008 C CD2 . TYR A 1 269 ? 30.189 59.003 10.592 1.00 10.29 ? 269 TYR A CD2 1 ATOM 2009 C CE1 . TYR A 1 269 ? 31.025 60.691 12.666 1.00 10.15 ? 269 TYR A CE1 1 ATOM 2010 C CE2 . TYR A 1 269 ? 30.587 60.315 10.308 1.00 11.28 ? 269 TYR A CE2 1 ATOM 2011 C CZ . TYR A 1 269 ? 31.007 61.157 11.350 1.00 12.06 ? 269 TYR A CZ 1 ATOM 2012 O OH . TYR A 1 269 ? 31.388 62.442 11.034 1.00 12.53 ? 269 TYR A OH 1 ATOM 2013 N N . ASP A 1 270 ? 27.628 58.615 14.602 1.00 9.44 ? 270 ASP A N 1 ATOM 2014 C CA . ASP A 1 270 ? 27.723 59.151 15.962 1.00 10.28 ? 270 ASP A CA 1 ATOM 2015 C C . ASP A 1 270 ? 27.167 58.111 16.962 1.00 11.61 ? 270 ASP A C 1 ATOM 2016 O O . ASP A 1 270 ? 26.607 57.086 16.555 1.00 11.48 ? 270 ASP A O 1 ATOM 2017 C CB . ASP A 1 270 ? 27.036 60.539 16.075 1.00 11.09 ? 270 ASP A CB 1 ATOM 2018 C CG . ASP A 1 270 ? 25.516 60.489 15.896 1.00 12.05 ? 270 ASP A CG 1 ATOM 2019 O OD1 . ASP A 1 270 ? 24.931 59.374 15.850 1.00 12.18 ? 270 ASP A OD1 1 ATOM 2020 O OD2 . ASP A 1 270 ? 24.909 61.594 15.836 1.00 12.78 ? 270 ASP A OD2 1 ATOM 2021 N N . ILE A 1 271 ? 27.363 58.334 18.256 1.00 11.04 ? 271 ILE A N 1 ATOM 2022 C CA . ILE A 1 271 ? 26.915 57.342 19.218 1.00 11.32 ? 271 ILE A CA 1 ATOM 2023 C C . ILE A 1 271 ? 25.405 57.070 19.192 1.00 10.73 ? 271 ILE A C 1 ATOM 2024 O O . ILE A 1 271 ? 25.003 55.910 19.238 1.00 11.70 ? 271 ILE A O 1 ATOM 2025 C CB . ILE A 1 271 ? 27.463 57.665 20.642 1.00 11.05 ? 271 ILE A CB 1 ATOM 2026 C CG1 . ILE A 1 271 ? 28.995 57.542 20.605 1.00 9.65 ? 271 ILE A CG1 1 ATOM 2027 C CG2 . ILE A 1 271 ? 26.921 56.620 21.692 1.00 9.82 ? 271 ILE A CG2 1 ATOM 2028 C CD1 . ILE A 1 271 ? 29.729 58.213 21.779 1.00 10.79 ? 271 ILE A CD1 1 ATOM 2029 N N . PRO A 1 272 ? 24.557 58.107 19.076 1.00 11.36 ? 272 PRO A N 1 ATOM 2030 C CA . PRO A 1 272 ? 23.100 57.857 19.033 1.00 11.95 ? 272 PRO A CA 1 ATOM 2031 C C . PRO A 1 272 ? 22.687 56.899 17.899 1.00 12.45 ? 272 PRO A C 1 ATOM 2032 O O . PRO A 1 272 ? 21.657 56.227 17.986 1.00 13.68 ? 272 PRO A O 1 ATOM 2033 C CB . PRO A 1 272 ? 22.505 59.243 18.792 1.00 10.25 ? 272 PRO A CB 1 ATOM 2034 C CG . PRO A 1 272 ? 23.452 60.125 19.552 1.00 11.95 ? 272 PRO A CG 1 ATOM 2035 C CD . PRO A 1 272 ? 24.834 59.554 19.206 1.00 11.67 ? 272 PRO A CD 1 ATOM 2036 N N . HIS A 1 273 ? 23.483 56.853 16.836 1.00 11.85 ? 273 HIS A N 1 ATOM 2037 C CA . HIS A 1 273 ? 23.172 56.003 15.682 1.00 11.42 ? 273 HIS A CA 1 ATOM 2038 C C . HIS A 1 273 ? 24.097 54.803 15.479 1.00 12.04 ? 273 HIS A C 1 ATOM 2039 O O . HIS A 1 273 ? 24.184 54.230 14.360 1.00 11.50 ? 273 HIS A O 1 ATOM 2040 C CB . HIS A 1 273 ? 23.131 56.870 14.411 1.00 10.57 ? 273 HIS A CB 1 ATOM 2041 C CG . HIS A 1 273 ? 22.060 57.921 14.459 1.00 11.47 ? 273 HIS A CG 1 ATOM 2042 N ND1 . HIS A 1 273 ? 22.274 59.189 14.962 1.00 13.12 ? 273 HIS A ND1 1 ATOM 2043 C CD2 . HIS A 1 273 ? 20.746 57.862 14.134 1.00 12.47 ? 273 HIS A CD2 1 ATOM 2044 C CE1 . HIS A 1 273 ? 21.134 59.863 14.941 1.00 13.03 ? 273 HIS A CE1 1 ATOM 2045 N NE2 . HIS A 1 273 ? 20.194 59.077 14.445 1.00 12.21 ? 273 HIS A NE2 1 ATOM 2046 N N . THR A 1 274 ? 24.778 54.405 16.548 1.00 11.46 ? 274 THR A N 1 ATOM 2047 C CA . THR A 1 274 ? 25.663 53.264 16.447 1.00 11.77 ? 274 THR A CA 1 ATOM 2048 C C . THR A 1 274 ? 25.454 52.156 17.498 1.00 12.24 ? 274 THR A C 1 ATOM 2049 O O . THR A 1 274 ? 25.986 51.069 17.314 1.00 13.70 ? 274 THR A O 1 ATOM 2050 C CB . THR A 1 274 ? 27.151 53.702 16.430 1.00 11.89 ? 274 THR A CB 1 ATOM 2051 O OG1 . THR A 1 274 ? 27.410 54.629 17.485 1.00 11.93 ? 274 THR A OG1 1 ATOM 2052 C CG2 . THR A 1 274 ? 27.494 54.317 15.083 1.00 10.63 ? 274 THR A CG2 1 ATOM 2053 N N . CYS A 1 275 ? 24.657 52.385 18.551 1.00 12.44 ? 275 CYS A N 1 ATOM 2054 C CA . CYS A 1 275 ? 24.454 51.312 19.537 1.00 12.97 ? 275 CYS A CA 1 ATOM 2055 C C . CYS A 1 275 ? 23.298 50.396 19.150 1.00 13.10 ? 275 CYS A C 1 ATOM 2056 O O . CYS A 1 275 ? 23.227 49.251 19.598 1.00 12.56 ? 275 CYS A O 1 ATOM 2057 C CB . CYS A 1 275 ? 24.173 51.879 20.948 1.00 13.99 ? 275 CYS A CB 1 ATOM 2058 S SG . CYS A 1 275 ? 22.397 51.992 21.429 1.00 14.25 ? 275 CYS A SG 1 ATOM 2059 N N . GLY A 1 276 ? 22.394 50.912 18.320 1.00 13.70 ? 276 GLY A N 1 ATOM 2060 C CA . GLY A 1 276 ? 21.226 50.153 17.900 1.00 13.31 ? 276 GLY A CA 1 ATOM 2061 C C . GLY A 1 276 ? 20.262 51.051 17.136 1.00 12.66 ? 276 GLY A C 1 ATOM 2062 O O . GLY A 1 276 ? 20.608 52.214 16.885 1.00 12.27 ? 276 GLY A O 1 ATOM 2063 N N . PRO A 1 277 ? 19.034 50.572 16.812 1.00 10.72 ? 277 PRO A N 1 ATOM 2064 C CA . PRO A 1 277 ? 18.027 51.330 16.059 1.00 11.78 ? 277 PRO A CA 1 ATOM 2065 C C . PRO A 1 277 ? 17.382 52.570 16.645 1.00 12.17 ? 277 PRO A C 1 ATOM 2066 O O . PRO A 1 277 ? 16.873 53.394 15.907 1.00 13.20 ? 277 PRO A O 1 ATOM 2067 C CB . PRO A 1 277 ? 16.962 50.260 15.716 1.00 11.96 ? 277 PRO A CB 1 ATOM 2068 C CG . PRO A 1 277 ? 17.008 49.342 16.890 1.00 9.87 ? 277 PRO A CG 1 ATOM 2069 C CD . PRO A 1 277 ? 18.521 49.239 17.190 1.00 10.70 ? 277 PRO A CD 1 ATOM 2070 N N . ASP A 1 278 ? 17.414 52.710 17.962 1.00 12.94 ? 278 ASP A N 1 ATOM 2071 C CA . ASP A 1 278 ? 16.740 53.824 18.618 1.00 13.98 ? 278 ASP A CA 1 ATOM 2072 C C . ASP A 1 278 ? 17.688 54.862 19.172 1.00 13.88 ? 278 ASP A C 1 ATOM 2073 O O . ASP A 1 278 ? 18.249 54.684 20.248 1.00 14.68 ? 278 ASP A O 1 ATOM 2074 C CB . ASP A 1 278 ? 15.857 53.297 19.754 1.00 15.29 ? 278 ASP A CB 1 ATOM 2075 C CG . ASP A 1 278 ? 14.966 54.393 20.350 1.00 17.39 ? 278 ASP A CG 1 ATOM 2076 O OD1 . ASP A 1 278 ? 15.110 55.580 19.954 1.00 17.23 ? 278 ASP A OD1 1 ATOM 2077 O OD2 . ASP A 1 278 ? 14.138 54.051 21.212 1.00 19.09 ? 278 ASP A OD2 1 ATOM 2078 N N . PRO A 1 279 ? 17.858 55.972 18.453 1.00 13.56 ? 279 PRO A N 1 ATOM 2079 C CA . PRO A 1 279 ? 18.765 57.035 18.908 1.00 14.11 ? 279 PRO A CA 1 ATOM 2080 C C . PRO A 1 279 ? 18.387 57.636 20.243 1.00 14.38 ? 279 PRO A C 1 ATOM 2081 O O . PRO A 1 279 ? 19.244 58.148 20.932 1.00 14.85 ? 279 PRO A O 1 ATOM 2082 C CB . PRO A 1 279 ? 18.712 58.055 17.768 1.00 12.69 ? 279 PRO A CB 1 ATOM 2083 C CG . PRO A 1 279 ? 17.285 57.872 17.247 1.00 15.28 ? 279 PRO A CG 1 ATOM 2084 C CD . PRO A 1 279 ? 17.150 56.365 17.222 1.00 13.43 ? 279 PRO A CD 1 ATOM 2085 N N . LYS A 1 280 ? 17.112 57.578 20.621 1.00 15.30 ? 280 LYS A N 1 ATOM 2086 C CA . LYS A 1 280 ? 16.694 58.158 21.905 1.00 16.51 ? 280 LYS A CA 1 ATOM 2087 C C . LYS A 1 280 ? 17.310 57.342 23.020 1.00 16.04 ? 280 LYS A C 1 ATOM 2088 O O . LYS A 1 280 ? 17.622 57.857 24.104 1.00 17.29 ? 280 LYS A O 1 ATOM 2089 C CB . LYS A 1 280 ? 15.170 58.142 22.037 1.00 18.14 ? 280 LYS A CB 1 ATOM 2090 C CG . LYS A 1 280 ? 14.647 58.588 23.396 1.00 20.71 ? 280 LYS A CG 1 ATOM 2091 C CD . LYS A 1 280 ? 13.132 58.735 23.363 1.00 23.91 ? 280 LYS A CD 1 ATOM 2092 C CE . LYS A 1 280 ? 12.374 57.401 23.493 1.00 27.96 ? 280 LYS A CE 1 ATOM 2093 N NZ . LYS A 1 280 ? 12.489 56.292 22.416 1.00 31.28 ? 280 LYS A NZ 1 ATOM 2094 N N . VAL A 1 281 ? 17.500 56.057 22.752 1.00 16.08 ? 281 VAL A N 1 ATOM 2095 C CA . VAL A 1 281 ? 18.111 55.172 23.742 1.00 15.64 ? 281 VAL A CA 1 ATOM 2096 C C . VAL A 1 281 ? 19.640 55.227 23.657 1.00 15.25 ? 281 VAL A C 1 ATOM 2097 O O . VAL A 1 281 ? 20.322 55.420 24.670 1.00 14.12 ? 281 VAL A O 1 ATOM 2098 C CB . VAL A 1 281 ? 17.649 53.715 23.547 1.00 16.78 ? 281 VAL A CB 1 ATOM 2099 C CG1 . VAL A 1 281 ? 18.477 52.785 24.467 1.00 15.39 ? 281 VAL A CG1 1 ATOM 2100 C CG2 . VAL A 1 281 ? 16.109 53.605 23.827 1.00 16.71 ? 281 VAL A CG2 1 ATOM 2101 N N . CYS A 1 282 ? 20.183 55.070 22.448 1.00 14.91 ? 282 CYS A N 1 ATOM 2102 C CA . CYS A 1 282 ? 21.636 55.109 22.279 1.00 14.29 ? 282 CYS A CA 1 ATOM 2103 C C . CYS A 1 282 ? 22.263 56.418 22.786 1.00 14.19 ? 282 CYS A C 1 ATOM 2104 O O . CYS A 1 282 ? 23.381 56.421 23.329 1.00 14.81 ? 282 CYS A O 1 ATOM 2105 C CB . CYS A 1 282 ? 21.998 54.941 20.807 1.00 13.77 ? 282 CYS A CB 1 ATOM 2106 S SG . CYS A 1 282 ? 21.589 53.317 20.114 1.00 14.67 ? 282 CYS A SG 1 ATOM 2107 N N . CYS A 1 283 ? 21.557 57.530 22.613 1.00 13.05 ? 283 CYS A N 1 ATOM 2108 C CA . CYS A 1 283 ? 22.098 58.803 23.062 1.00 13.71 ? 283 CYS A CA 1 ATOM 2109 C C . CYS A 1 283 ? 22.407 58.769 24.560 1.00 14.21 ? 283 CYS A C 1 ATOM 2110 O O . CYS A 1 283 ? 23.356 59.411 25.044 1.00 13.97 ? 283 CYS A O 1 ATOM 2111 C CB . CYS A 1 283 ? 21.144 59.963 22.720 1.00 14.56 ? 283 CYS A CB 1 ATOM 2112 S SG . CYS A 1 283 ? 22.016 61.578 22.856 1.00 13.60 ? 283 CYS A SG 1 ATOM 2113 N N . GLN A 1 284 ? 21.630 57.990 25.296 1.00 13.37 ? 284 GLN A N 1 ATOM 2114 C CA . GLN A 1 284 ? 21.850 57.911 26.721 1.00 15.05 ? 284 GLN A CA 1 ATOM 2115 C C . GLN A 1 284 ? 23.133 57.173 27.044 1.00 14.70 ? 284 GLN A C 1 ATOM 2116 O O . GLN A 1 284 ? 23.521 57.082 28.214 1.00 16.23 ? 284 GLN A O 1 ATOM 2117 C CB . GLN A 1 284 ? 20.672 57.218 27.396 1.00 14.40 ? 284 GLN A CB 1 ATOM 2118 C CG . GLN A 1 284 ? 19.353 57.934 27.199 1.00 14.73 ? 284 GLN A CG 1 ATOM 2119 C CD . GLN A 1 284 ? 18.213 57.120 27.769 1.00 15.80 ? 284 GLN A CD 1 ATOM 2120 O OE1 . GLN A 1 284 ? 18.222 56.765 28.942 1.00 17.21 ? 284 GLN A OE1 1 ATOM 2121 N NE2 . GLN A 1 284 ? 17.237 56.802 26.932 1.00 19.41 ? 284 GLN A NE2 1 ATOM 2122 N N . PHE A 1 285 ? 23.797 56.630 26.027 1.00 14.57 ? 285 PHE A N 1 ATOM 2123 C CA . PHE A 1 285 ? 25.039 55.925 26.291 1.00 13.59 ? 285 PHE A CA 1 ATOM 2124 C C . PHE A 1 285 ? 26.244 56.626 25.688 1.00 13.41 ? 285 PHE A C 1 ATOM 2125 O O . PHE A 1 285 ? 27.287 56.026 25.444 1.00 14.30 ? 285 PHE A O 1 ATOM 2126 C CB . PHE A 1 285 ? 24.916 54.458 25.857 1.00 13.78 ? 285 PHE A CB 1 ATOM 2127 C CG . PHE A 1 285 ? 23.912 53.661 26.715 1.00 14.81 ? 285 PHE A CG 1 ATOM 2128 C CD1 . PHE A 1 285 ? 24.334 52.994 27.864 1.00 15.05 ? 285 PHE A CD1 1 ATOM 2129 C CD2 . PHE A 1 285 ? 22.557 53.653 26.398 1.00 15.58 ? 285 PHE A CD2 1 ATOM 2130 C CE1 . PHE A 1 285 ? 23.424 52.326 28.699 1.00 15.93 ? 285 PHE A CE1 1 ATOM 2131 C CE2 . PHE A 1 285 ? 21.619 52.991 27.218 1.00 16.40 ? 285 PHE A CE2 1 ATOM 2132 C CZ . PHE A 1 285 ? 22.053 52.327 28.371 1.00 16.62 ? 285 PHE A CZ 1 ATOM 2133 N N . ASP A 1 286 ? 26.065 57.910 25.428 1.00 13.33 ? 286 ASP A N 1 ATOM 2134 C CA . ASP A 1 286 ? 27.150 58.758 24.970 1.00 12.65 ? 286 ASP A CA 1 ATOM 2135 C C . ASP A 1 286 ? 27.359 59.562 26.260 1.00 13.02 ? 286 ASP A C 1 ATOM 2136 O O . ASP A 1 286 ? 26.709 60.573 26.495 1.00 11.73 ? 286 ASP A O 1 ATOM 2137 C CB . ASP A 1 286 ? 26.712 59.666 23.826 1.00 12.18 ? 286 ASP A CB 1 ATOM 2138 C CG . ASP A 1 286 ? 27.856 60.515 23.314 1.00 13.15 ? 286 ASP A CG 1 ATOM 2139 O OD1 . ASP A 1 286 ? 28.845 60.630 24.051 1.00 11.61 ? 286 ASP A OD1 1 ATOM 2140 O OD2 . ASP A 1 286 ? 27.765 61.076 22.200 1.00 13.87 ? 286 ASP A OD2 1 ATOM 2141 N N . PHE A 1 287 ? 28.280 59.107 27.103 1.00 12.96 ? 287 PHE A N 1 ATOM 2142 C CA . PHE A 1 287 ? 28.467 59.760 28.366 1.00 13.61 ? 287 PHE A CA 1 ATOM 2143 C C . PHE A 1 287 ? 29.060 61.153 28.375 1.00 14.73 ? 287 PHE A C 1 ATOM 2144 O O . PHE A 1 287 ? 29.233 61.746 29.436 1.00 12.99 ? 287 PHE A O 1 ATOM 2145 C CB . PHE A 1 287 ? 29.205 58.802 29.306 1.00 12.72 ? 287 PHE A CB 1 ATOM 2146 C CG . PHE A 1 287 ? 28.412 57.525 29.580 1.00 13.13 ? 287 PHE A CG 1 ATOM 2147 C CD1 . PHE A 1 287 ? 28.591 56.395 28.791 1.00 11.56 ? 287 PHE A CD1 1 ATOM 2148 C CD2 . PHE A 1 287 ? 27.447 57.485 30.584 1.00 11.97 ? 287 PHE A CD2 1 ATOM 2149 C CE1 . PHE A 1 287 ? 27.830 55.252 28.989 1.00 12.02 ? 287 PHE A CE1 1 ATOM 2150 C CE2 . PHE A 1 287 ? 26.659 56.323 30.798 1.00 12.83 ? 287 PHE A CE2 1 ATOM 2151 C CZ . PHE A 1 287 ? 26.857 55.202 29.992 1.00 10.18 ? 287 PHE A CZ 1 ATOM 2152 N N . LYS A 1 288 ? 29.350 61.680 27.191 1.00 15.50 ? 288 LYS A N 1 ATOM 2153 C CA . LYS A 1 288 ? 29.869 63.025 27.089 1.00 14.99 ? 288 LYS A CA 1 ATOM 2154 C C . LYS A 1 288 ? 28.691 64.001 27.022 1.00 15.98 ? 288 LYS A C 1 ATOM 2155 O O . LYS A 1 288 ? 28.884 65.216 27.012 1.00 16.88 ? 288 LYS A O 1 ATOM 2156 C CB . LYS A 1 288 ? 30.738 63.183 25.814 1.00 15.80 ? 288 LYS A CB 1 ATOM 2157 C CG . LYS A 1 288 ? 31.460 64.564 25.753 1.00 15.36 ? 288 LYS A CG 1 ATOM 2158 C CD . LYS A 1 288 ? 32.426 64.717 24.570 1.00 14.36 ? 288 LYS A CD 1 ATOM 2159 C CE . LYS A 1 288 ? 33.187 66.055 24.675 1.00 16.23 ? 288 LYS A CE 1 ATOM 2160 N NZ . LYS A 1 288 ? 34.208 66.223 23.557 1.00 18.86 ? 288 LYS A NZ 1 ATOM 2161 N N . ARG A 1 289 ? 27.460 63.496 26.999 1.00 16.09 ? 289 ARG A N 1 ATOM 2162 C CA . ARG A 1 289 ? 26.326 64.404 26.878 1.00 17.95 ? 289 ARG A CA 1 ATOM 2163 C C . ARG A 1 289 ? 25.554 64.682 28.156 1.00 19.52 ? 289 ARG A C 1 ATOM 2164 O O . ARG A 1 289 ? 24.347 64.863 28.104 1.00 18.93 ? 289 ARG A O 1 ATOM 2165 C CB . ARG A 1 289 ? 25.349 63.878 25.816 1.00 16.63 ? 289 ARG A CB 1 ATOM 2166 C CG . ARG A 1 289 ? 26.012 63.628 24.431 1.00 14.92 ? 289 ARG A CG 1 ATOM 2167 C CD . ARG A 1 289 ? 24.952 63.363 23.387 1.00 13.80 ? 289 ARG A CD 1 ATOM 2168 N NE . ARG A 1 289 ? 25.478 62.958 22.080 1.00 12.97 ? 289 ARG A NE 1 ATOM 2169 C CZ . ARG A 1 289 ? 25.073 63.486 20.924 1.00 13.36 ? 289 ARG A CZ 1 ATOM 2170 N NH1 . ARG A 1 289 ? 24.151 64.452 20.914 1.00 10.60 ? 289 ARG A NH1 1 ATOM 2171 N NH2 . ARG A 1 289 ? 25.540 63.004 19.773 1.00 12.41 ? 289 ARG A NH2 1 ATOM 2172 N N . MET A 1 290 ? 26.226 64.749 29.297 1.00 22.03 ? 290 MET A N 1 ATOM 2173 C CA . MET A 1 290 ? 25.468 64.983 30.530 1.00 24.42 ? 290 MET A CA 1 ATOM 2174 C C . MET A 1 290 ? 25.347 66.453 30.972 1.00 25.46 ? 290 MET A C 1 ATOM 2175 O O . MET A 1 290 ? 24.540 66.753 31.901 1.00 27.36 ? 290 MET A O 1 ATOM 2176 C CB . MET A 1 290 ? 25.991 64.085 31.669 1.00 24.23 ? 290 MET A CB 1 ATOM 2177 C CG . MET A 1 290 ? 25.746 62.599 31.414 1.00 25.68 ? 290 MET A CG 1 ATOM 2178 S SD . MET A 1 290 ? 26.206 61.442 32.761 1.00 28.89 ? 290 MET A SD 1 ATOM 2179 C CE . MET A 1 290 ? 28.031 61.443 32.571 1.00 26.75 ? 290 MET A CE 1 ATOM 2180 N N . GLY A 1 291 ? 26.106 67.357 30.319 1.00 24.62 ? 291 GLY A N 1 ATOM 2181 C CA . GLY A 1 291 ? 26.031 68.783 30.636 1.00 23.09 ? 291 GLY A CA 1 ATOM 2182 C C . GLY A 1 291 ? 27.298 69.644 30.718 1.00 23.12 ? 291 GLY A C 1 ATOM 2183 O O . GLY A 1 291 ? 27.394 70.714 30.072 1.00 21.92 ? 291 GLY A O 1 ATOM 2184 N N . SER A 1 292 ? 28.273 69.190 31.511 1.00 20.36 ? 292 SER A N 1 ATOM 2185 C CA . SER A 1 292 ? 29.511 69.922 31.712 1.00 19.13 ? 292 SER A CA 1 ATOM 2186 C C . SER A 1 292 ? 30.329 70.114 30.438 1.00 18.83 ? 292 SER A C 1 ATOM 2187 O O . SER A 1 292 ? 31.178 71.004 30.396 1.00 17.92 ? 292 SER A O 1 ATOM 2188 C CB . SER A 1 292 ? 30.367 69.209 32.753 1.00 20.27 ? 292 SER A CB 1 ATOM 2189 O OG . SER A 1 292 ? 30.813 67.953 32.247 1.00 21.51 ? 292 SER A OG 1 ATOM 2190 N N . PHE A 1 293 ? 30.093 69.273 29.421 1.00 17.69 ? 293 PHE A N 1 ATOM 2191 C CA . PHE A 1 293 ? 30.804 69.367 28.145 1.00 17.23 ? 293 PHE A CA 1 ATOM 2192 C C . PHE A 1 293 ? 30.033 70.230 27.131 1.00 17.62 ? 293 PHE A C 1 ATOM 2193 O O . PHE A 1 293 ? 30.468 70.399 26.004 1.00 16.92 ? 293 PHE A O 1 ATOM 2194 C CB . PHE A 1 293 ? 31.041 67.967 27.526 1.00 16.76 ? 293 PHE A CB 1 ATOM 2195 C CG . PHE A 1 293 ? 31.965 67.091 28.328 1.00 16.08 ? 293 PHE A CG 1 ATOM 2196 C CD1 . PHE A 1 293 ? 31.455 66.168 29.230 1.00 16.94 ? 293 PHE A CD1 1 ATOM 2197 C CD2 . PHE A 1 293 ? 33.337 67.189 28.171 1.00 15.54 ? 293 PHE A CD2 1 ATOM 2198 C CE1 . PHE A 1 293 ? 32.315 65.341 29.969 1.00 17.59 ? 293 PHE A CE1 1 ATOM 2199 C CE2 . PHE A 1 293 ? 34.218 66.372 28.896 1.00 16.67 ? 293 PHE A CE2 1 ATOM 2200 C CZ . PHE A 1 293 ? 33.709 65.444 29.798 1.00 17.31 ? 293 PHE A CZ 1 ATOM 2201 N N . GLY A 1 294 ? 28.875 70.753 27.526 1.00 18.17 ? 294 GLY A N 1 ATOM 2202 C CA . GLY A 1 294 ? 28.106 71.576 26.604 1.00 19.03 ? 294 GLY A CA 1 ATOM 2203 C C . GLY A 1 294 ? 27.384 70.779 25.521 1.00 19.40 ? 294 GLY A C 1 ATOM 2204 O O . GLY A 1 294 ? 27.069 71.308 24.453 1.00 19.65 ? 294 GLY A O 1 ATOM 2205 N N . LEU A 1 295 ? 27.127 69.501 25.779 1.00 18.50 ? 295 LEU A N 1 ATOM 2206 C CA . LEU A 1 295 ? 26.425 68.659 24.809 1.00 18.69 ? 295 LEU A CA 1 ATOM 2207 C C . LEU A 1 295 ? 25.192 68.066 25.493 1.00 18.42 ? 295 LEU A C 1 ATOM 2208 O O . LEU A 1 295 ? 25.130 67.974 26.723 1.00 18.40 ? 295 LEU A O 1 ATOM 2209 C CB . LEU A 1 295 ? 27.344 67.533 24.300 1.00 19.47 ? 295 LEU A CB 1 ATOM 2210 C CG . LEU A 1 295 ? 28.623 67.943 23.528 1.00 21.06 ? 295 LEU A CG 1 ATOM 2211 C CD1 . LEU A 1 295 ? 29.570 66.744 23.373 1.00 19.19 ? 295 LEU A CD1 1 ATOM 2212 C CD2 . LEU A 1 295 ? 28.240 68.512 22.150 1.00 20.32 ? 295 LEU A CD2 1 ATOM 2213 N N . SER A 1 296 ? 24.195 67.688 24.709 1.00 18.79 ? 296 SER A N 1 ATOM 2214 C CA . SER A 1 296 ? 23.000 67.097 25.298 1.00 19.17 ? 296 SER A CA 1 ATOM 2215 C C . SER A 1 296 ? 22.387 66.211 24.237 1.00 18.39 ? 296 SER A C 1 ATOM 2216 O O . SER A 1 296 ? 22.873 66.194 23.114 1.00 17.11 ? 296 SER A O 1 ATOM 2217 C CB . SER A 1 296 ? 22.013 68.198 25.744 1.00 18.52 ? 296 SER A CB 1 ATOM 2218 O OG . SER A 1 296 ? 21.682 69.065 24.674 1.00 20.32 ? 296 SER A OG 1 ATOM 2219 N N . CYS A 1 297 ? 21.334 65.485 24.614 1.00 18.22 ? 297 CYS A N 1 ATOM 2220 C CA . CYS A 1 297 ? 20.624 64.569 23.728 1.00 18.57 ? 297 CYS A CA 1 ATOM 2221 C C . CYS A 1 297 ? 19.403 65.240 23.140 1.00 19.56 ? 297 CYS A C 1 ATOM 2222 O O . CYS A 1 297 ? 18.499 65.665 23.859 1.00 19.79 ? 297 CYS A O 1 ATOM 2223 C CB . CYS A 1 297 ? 20.207 63.317 24.498 1.00 17.56 ? 297 CYS A CB 1 ATOM 2224 S SG . CYS A 1 297 ? 21.632 62.224 24.764 1.00 17.58 ? 297 CYS A SG 1 ATOM 2225 N N . PRO A 1 298 ? 19.357 65.348 21.815 1.00 20.34 ? 298 PRO A N 1 ATOM 2226 C CA . PRO A 1 298 ? 18.182 65.998 21.231 1.00 20.69 ? 298 PRO A CA 1 ATOM 2227 C C . PRO A 1 298 ? 16.861 65.248 21.467 1.00 20.91 ? 298 PRO A C 1 ATOM 2228 O O . PRO A 1 298 ? 15.787 65.842 21.352 1.00 19.18 ? 298 PRO A O 1 ATOM 2229 C CB . PRO A 1 298 ? 18.558 66.140 19.748 1.00 21.63 ? 298 PRO A CB 1 ATOM 2230 C CG . PRO A 1 298 ? 19.580 65.037 19.524 1.00 21.77 ? 298 PRO A CG 1 ATOM 2231 C CD . PRO A 1 298 ? 20.390 65.046 20.801 1.00 20.94 ? 298 PRO A CD 1 ATOM 2232 N N . TRP A 1 299 ? 16.945 63.963 21.826 1.00 19.76 ? 299 TRP A N 1 ATOM 2233 C CA . TRP A 1 299 ? 15.738 63.168 22.090 1.00 20.90 ? 299 TRP A CA 1 ATOM 2234 C C . TRP A 1 299 ? 15.189 63.392 23.502 1.00 21.09 ? 299 TRP A C 1 ATOM 2235 O O . TRP A 1 299 ? 14.280 62.699 23.921 1.00 21.69 ? 299 TRP A O 1 ATOM 2236 C CB . TRP A 1 299 ? 16.010 61.670 21.827 1.00 18.90 ? 299 TRP A CB 1 ATOM 2237 C CG . TRP A 1 299 ? 16.370 61.453 20.372 1.00 17.80 ? 299 TRP A CG 1 ATOM 2238 C CD1 . TRP A 1 299 ? 15.507 61.266 19.342 1.00 17.42 ? 299 TRP A CD1 1 ATOM 2239 C CD2 . TRP A 1 299 ? 17.684 61.531 19.785 1.00 18.66 ? 299 TRP A CD2 1 ATOM 2240 N NE1 . TRP A 1 299 ? 16.189 61.224 18.148 1.00 19.74 ? 299 TRP A NE1 1 ATOM 2241 C CE2 . TRP A 1 299 ? 17.525 61.386 18.389 1.00 18.43 ? 299 TRP A CE2 1 ATOM 2242 C CE3 . TRP A 1 299 ? 18.977 61.710 20.307 1.00 16.37 ? 299 TRP A CE3 1 ATOM 2243 C CZ2 . TRP A 1 299 ? 18.613 61.415 17.496 1.00 18.89 ? 299 TRP A CZ2 1 ATOM 2244 C CZ3 . TRP A 1 299 ? 20.054 61.734 19.425 1.00 17.53 ? 299 TRP A CZ3 1 ATOM 2245 C CH2 . TRP A 1 299 ? 19.866 61.588 18.032 1.00 16.99 ? 299 TRP A CH2 1 ATOM 2246 N N . LYS A 1 300 ? 15.774 64.352 24.224 1.00 22.78 ? 300 LYS A N 1 ATOM 2247 C CA . LYS A 1 300 ? 15.331 64.745 25.569 1.00 24.06 ? 300 LYS A CA 1 ATOM 2248 C C . LYS A 1 300 ? 15.531 63.795 26.755 1.00 23.86 ? 300 LYS A C 1 ATOM 2249 O O . LYS A 1 300 ? 15.027 64.055 27.847 1.00 24.58 ? 300 LYS A O 1 ATOM 2250 C CB . LYS A 1 300 ? 13.862 65.190 25.503 1.00 24.49 ? 300 LYS A CB 1 ATOM 2251 C CG . LYS A 1 300 ? 13.645 66.402 24.599 1.00 27.81 ? 300 LYS A CG 1 ATOM 2252 C CD . LYS A 1 300 ? 12.155 66.693 24.432 1.00 30.45 ? 300 LYS A CD 1 ATOM 2253 C CE . LYS A 1 300 ? 11.909 68.083 23.875 1.00 32.30 ? 300 LYS A CE 1 ATOM 2254 N NZ . LYS A 1 300 ? 12.830 68.395 22.733 1.00 33.91 ? 300 LYS A NZ 1 ATOM 2255 N N . VAL A 1 301 ? 16.234 62.685 26.556 1.00 22.86 ? 301 VAL A N 1 ATOM 2256 C CA . VAL A 1 301 ? 16.527 61.787 27.659 1.00 22.43 ? 301 VAL A CA 1 ATOM 2257 C C . VAL A 1 301 ? 18.053 61.806 27.678 1.00 22.87 ? 301 VAL A C 1 ATOM 2258 O O . VAL A 1 301 ? 18.694 61.388 26.717 1.00 22.26 ? 301 VAL A O 1 ATOM 2259 C CB . VAL A 1 301 ? 16.021 60.361 27.414 1.00 22.99 ? 301 VAL A CB 1 ATOM 2260 C CG1 . VAL A 1 301 ? 16.406 59.499 28.588 1.00 22.19 ? 301 VAL A CG1 1 ATOM 2261 C CG2 . VAL A 1 301 ? 14.474 60.360 27.239 1.00 22.83 ? 301 VAL A CG2 1 ATOM 2262 N N . PRO A 1 302 ? 18.649 62.306 28.770 1.00 22.28 ? 302 PRO A N 1 ATOM 2263 C CA . PRO A 1 302 ? 20.102 62.409 28.924 1.00 21.63 ? 302 PRO A CA 1 ATOM 2264 C C . PRO A 1 302 ? 20.782 61.152 29.410 1.00 21.06 ? 302 PRO A C 1 ATOM 2265 O O . PRO A 1 302 ? 20.132 60.232 29.888 1.00 19.78 ? 302 PRO A O 1 ATOM 2266 C CB . PRO A 1 302 ? 20.244 63.542 29.931 1.00 22.14 ? 302 PRO A CB 1 ATOM 2267 C CG . PRO A 1 302 ? 19.113 63.259 30.874 1.00 22.76 ? 302 PRO A CG 1 ATOM 2268 C CD . PRO A 1 302 ? 17.956 62.851 29.956 1.00 22.89 ? 302 PRO A CD 1 ATOM 2269 N N . PRO A 1 303 ? 22.113 61.073 29.240 1.00 20.64 ? 303 PRO A N 1 ATOM 2270 C CA . PRO A 1 303 ? 22.734 59.843 29.750 1.00 20.27 ? 303 PRO A CA 1 ATOM 2271 C C . PRO A 1 303 ? 22.805 59.979 31.281 1.00 20.16 ? 303 PRO A C 1 ATOM 2272 O O . PRO A 1 303 ? 22.766 61.096 31.818 1.00 17.84 ? 303 PRO A O 1 ATOM 2273 C CB . PRO A 1 303 ? 24.131 59.836 29.109 1.00 20.80 ? 303 PRO A CB 1 ATOM 2274 C CG . PRO A 1 303 ? 24.380 61.298 28.701 1.00 21.51 ? 303 PRO A CG 1 ATOM 2275 C CD . PRO A 1 303 ? 23.011 61.849 28.363 1.00 20.05 ? 303 PRO A CD 1 ATOM 2276 N N . ARG A 1 304 ? 22.914 58.854 31.975 1.00 20.91 ? 304 ARG A N 1 ATOM 2277 C CA . ARG A 1 304 ? 23.044 58.867 33.430 1.00 22.19 ? 304 ARG A CA 1 ATOM 2278 C C . ARG A 1 304 ? 24.238 58.030 33.847 1.00 21.37 ? 304 ARG A C 1 ATOM 2279 O O . ARG A 1 304 ? 24.459 56.950 33.314 1.00 20.71 ? 304 ARG A O 1 ATOM 2280 C CB . ARG A 1 304 ? 21.770 58.324 34.091 1.00 25.28 ? 304 ARG A CB 1 ATOM 2281 C CG . ARG A 1 304 ? 20.723 59.396 34.290 1.00 28.06 ? 304 ARG A CG 1 ATOM 2282 C CD . ARG A 1 304 ? 19.523 58.867 35.059 1.00 31.69 ? 304 ARG A CD 1 ATOM 2283 N NE . ARG A 1 304 ? 18.877 57.766 34.357 1.00 35.23 ? 304 ARG A NE 1 ATOM 2284 C CZ . ARG A 1 304 ? 18.644 56.572 34.894 1.00 37.26 ? 304 ARG A CZ 1 ATOM 2285 N NH1 . ARG A 1 304 ? 19.002 56.303 36.153 1.00 37.24 ? 304 ARG A NH1 1 ATOM 2286 N NH2 . ARG A 1 304 ? 18.048 55.643 34.158 1.00 39.57 ? 304 ARG A NH2 1 ATOM 2287 N N . THR A 1 305 ? 25.020 58.532 34.798 1.00 20.82 ? 305 THR A N 1 ATOM 2288 C CA . THR A 1 305 ? 26.192 57.801 35.265 1.00 19.90 ? 305 THR A CA 1 ATOM 2289 C C . THR A 1 305 ? 25.768 56.421 35.697 1.00 18.97 ? 305 THR A C 1 ATOM 2290 O O . THR A 1 305 ? 24.736 56.288 36.345 1.00 19.91 ? 305 THR A O 1 ATOM 2291 C CB . THR A 1 305 ? 26.848 58.547 36.427 1.00 20.25 ? 305 THR A CB 1 ATOM 2292 O OG1 . THR A 1 305 ? 27.337 59.792 35.925 1.00 21.85 ? 305 THR A OG1 1 ATOM 2293 C CG2 . THR A 1 305 ? 27.994 57.747 37.034 1.00 19.88 ? 305 THR A CG2 1 ATOM 2294 N N . ILE A 1 306 ? 26.532 55.394 35.313 1.00 18.07 ? 306 ILE A N 1 ATOM 2295 C CA . ILE A 1 306 ? 26.189 54.015 35.670 1.00 17.70 ? 306 ILE A CA 1 ATOM 2296 C C . ILE A 1 306 ? 26.607 53.757 37.108 1.00 18.34 ? 306 ILE A C 1 ATOM 2297 O O . ILE A 1 306 ? 27.685 54.176 37.531 1.00 16.70 ? 306 ILE A O 1 ATOM 2298 C CB . ILE A 1 306 ? 26.896 52.983 34.767 1.00 16.64 ? 306 ILE A CB 1 ATOM 2299 C CG1 . ILE A 1 306 ? 26.655 53.308 33.285 1.00 15.94 ? 306 ILE A CG1 1 ATOM 2300 C CG2 . ILE A 1 306 ? 26.372 51.542 35.082 1.00 17.46 ? 306 ILE A CG2 1 ATOM 2301 C CD1 . ILE A 1 306 ? 25.216 53.216 32.853 1.00 14.91 ? 306 ILE A CD1 1 ATOM 2302 N N . SER A 1 307 ? 25.752 53.063 37.858 1.00 19.35 ? 307 SER A N 1 ATOM 2303 C CA . SER A 1 307 ? 26.030 52.745 39.260 1.00 20.41 ? 307 SER A CA 1 ATOM 2304 C C . SER A 1 307 ? 25.532 51.350 39.517 1.00 21.56 ? 307 SER A C 1 ATOM 2305 O O . SER A 1 307 ? 24.914 50.737 38.647 1.00 21.09 ? 307 SER A O 1 ATOM 2306 C CB . SER A 1 307 ? 25.248 53.664 40.179 1.00 20.03 ? 307 SER A CB 1 ATOM 2307 O OG . SER A 1 307 ? 23.857 53.453 39.972 1.00 17.28 ? 307 SER A OG 1 ATOM 2308 N N . ASP A 1 308 ? 25.766 50.864 40.726 1.00 22.62 ? 308 ASP A N 1 ATOM 2309 C CA . ASP A 1 308 ? 25.311 49.536 41.077 1.00 24.54 ? 308 ASP A CA 1 ATOM 2310 C C . ASP A 1 308 ? 23.801 49.464 41.124 1.00 23.14 ? 308 ASP A C 1 ATOM 2311 O O . ASP A 1 308 ? 23.265 48.407 40.899 1.00 23.70 ? 308 ASP A O 1 ATOM 2312 C CB . ASP A 1 308 ? 25.888 49.087 42.418 1.00 27.35 ? 308 ASP A CB 1 ATOM 2313 C CG . ASP A 1 308 ? 27.382 48.883 42.357 1.00 29.99 ? 308 ASP A CG 1 ATOM 2314 O OD1 . ASP A 1 308 ? 27.901 48.707 41.242 1.00 31.44 ? 308 ASP A OD1 1 ATOM 2315 O OD2 . ASP A 1 308 ? 28.044 48.885 43.415 1.00 33.63 ? 308 ASP A OD2 1 ATOM 2316 N N . GLN A 1 309 ? 23.130 50.589 41.387 1.00 23.37 ? 309 GLN A N 1 ATOM 2317 C CA . GLN A 1 309 ? 21.661 50.642 41.447 1.00 23.38 ? 309 GLN A CA 1 ATOM 2318 C C . GLN A 1 309 ? 20.976 50.764 40.097 1.00 22.62 ? 309 GLN A C 1 ATOM 2319 O O . GLN A 1 309 ? 19.761 50.551 39.995 1.00 23.02 ? 309 GLN A O 1 ATOM 2320 C CB . GLN A 1 309 ? 21.159 51.833 42.282 1.00 24.64 ? 309 GLN A CB 1 ATOM 2321 C CG . GLN A 1 309 ? 21.472 51.783 43.764 1.00 26.79 ? 309 GLN A CG 1 ATOM 2322 C CD . GLN A 1 309 ? 22.961 51.887 44.029 1.00 28.05 ? 309 GLN A CD 1 ATOM 2323 O OE1 . GLN A 1 309 ? 23.631 52.776 43.494 1.00 27.95 ? 309 GLN A OE1 1 ATOM 2324 N NE2 . GLN A 1 309 ? 23.492 50.975 44.853 1.00 27.99 ? 309 GLN A NE2 1 ATOM 2325 N N . ASN A 1 310 ? 21.694 51.162 39.051 1.00 20.87 ? 310 ASN A N 1 ATOM 2326 C CA . ASN A 1 310 ? 20.972 51.279 37.788 1.00 19.63 ? 310 ASN A CA 1 ATOM 2327 C C . ASN A 1 310 ? 21.551 50.466 36.672 1.00 19.04 ? 310 ASN A C 1 ATOM 2328 O O . ASN A 1 310 ? 20.963 50.416 35.606 1.00 19.44 ? 310 ASN A O 1 ATOM 2329 C CB . ASN A 1 310 ? 20.854 52.746 37.324 1.00 18.09 ? 310 ASN A CB 1 ATOM 2330 C CG . ASN A 1 310 ? 22.202 53.371 36.926 1.00 18.25 ? 310 ASN A CG 1 ATOM 2331 O OD1 . ASN A 1 310 ? 23.193 52.658 36.654 1.00 15.78 ? 310 ASN A OD1 1 ATOM 2332 N ND2 . ASN A 1 310 ? 22.240 54.711 36.879 1.00 17.87 ? 310 ASN A ND2 1 ATOM 2333 N N . VAL A 1 311 ? 22.693 49.827 36.921 1.00 20.13 ? 311 VAL A N 1 ATOM 2334 C CA . VAL A 1 311 ? 23.385 49.059 35.874 1.00 18.12 ? 311 VAL A CA 1 ATOM 2335 C C . VAL A 1 311 ? 22.559 47.932 35.260 1.00 18.50 ? 311 VAL A C 1 ATOM 2336 O O . VAL A 1 311 ? 22.679 47.669 34.060 1.00 17.74 ? 311 VAL A O 1 ATOM 2337 C CB . VAL A 1 311 ? 24.713 48.505 36.387 1.00 18.08 ? 311 VAL A CB 1 ATOM 2338 C CG1 . VAL A 1 311 ? 24.474 47.509 37.532 1.00 18.26 ? 311 VAL A CG1 1 ATOM 2339 C CG2 . VAL A 1 311 ? 25.507 47.881 35.225 1.00 17.80 ? 311 VAL A CG2 1 ATOM 2340 N N . ALA A 1 312 ? 21.708 47.284 36.060 1.00 17.48 ? 312 ALA A N 1 ATOM 2341 C CA . ALA A 1 312 ? 20.892 46.192 35.545 1.00 17.77 ? 312 ALA A CA 1 ATOM 2342 C C . ALA A 1 312 ? 19.891 46.727 34.561 1.00 18.02 ? 312 ALA A C 1 ATOM 2343 O O . ALA A 1 312 ? 19.712 46.154 33.506 1.00 18.41 ? 312 ALA A O 1 ATOM 2344 C CB . ALA A 1 312 ? 20.163 45.433 36.695 1.00 19.46 ? 312 ALA A CB 1 ATOM 2345 N N . ALA A 1 313 ? 19.248 47.837 34.899 1.00 17.88 ? 313 ALA A N 1 ATOM 2346 C CA . ALA A 1 313 ? 18.260 48.454 34.024 1.00 18.44 ? 313 ALA A CA 1 ATOM 2347 C C . ALA A 1 313 ? 18.924 49.114 32.789 1.00 18.53 ? 313 ALA A C 1 ATOM 2348 O O . ALA A 1 313 ? 18.377 49.098 31.680 1.00 17.60 ? 313 ALA A O 1 ATOM 2349 C CB . ALA A 1 313 ? 17.464 49.496 34.798 1.00 17.12 ? 313 ALA A CB 1 ATOM 2350 N N . ARG A 1 314 ? 20.076 49.731 33.001 1.00 17.79 ? 314 ARG A N 1 ATOM 2351 C CA . ARG A 1 314 ? 20.790 50.378 31.892 1.00 18.73 ? 314 ARG A CA 1 ATOM 2352 C C . ARG A 1 314 ? 21.266 49.259 30.932 1.00 17.60 ? 314 ARG A C 1 ATOM 2353 O O . ARG A 1 314 ? 21.147 49.376 29.718 1.00 17.66 ? 314 ARG A O 1 ATOM 2354 C CB . ARG A 1 314 ? 21.983 51.142 32.445 1.00 18.64 ? 314 ARG A CB 1 ATOM 2355 C CG . ARG A 1 314 ? 21.610 52.338 33.301 1.00 20.43 ? 314 ARG A CG 1 ATOM 2356 C CD . ARG A 1 314 ? 21.271 53.573 32.460 1.00 21.79 ? 314 ARG A CD 1 ATOM 2357 N NE . ARG A 1 314 ? 19.883 53.601 32.032 1.00 22.85 ? 314 ARG A NE 1 ATOM 2358 C CZ . ARG A 1 314 ? 19.361 54.523 31.235 1.00 23.14 ? 314 ARG A CZ 1 ATOM 2359 N NH1 . ARG A 1 314 ? 20.115 55.506 30.752 1.00 24.02 ? 314 ARG A NH1 1 ATOM 2360 N NH2 . ARG A 1 314 ? 18.066 54.489 30.942 1.00 24.03 ? 314 ARG A NH2 1 ATOM 2361 N N . SER A 1 315 ? 21.796 48.175 31.488 1.00 18.15 ? 315 SER A N 1 ATOM 2362 C CA . SER A 1 315 ? 22.256 47.055 30.670 1.00 18.99 ? 315 SER A CA 1 ATOM 2363 C C . SER A 1 315 ? 21.080 46.429 29.897 1.00 20.89 ? 315 SER A C 1 ATOM 2364 O O . SER A 1 315 ? 21.243 46.024 28.751 1.00 21.95 ? 315 SER A O 1 ATOM 2365 C CB . SER A 1 315 ? 22.943 46.003 31.549 1.00 17.98 ? 315 SER A CB 1 ATOM 2366 O OG . SER A 1 315 ? 24.163 46.507 32.076 1.00 15.48 ? 315 SER A OG 1 ATOM 2367 N N . ASP A 1 316 ? 19.903 46.350 30.519 1.00 21.63 ? 316 ASP A N 1 ATOM 2368 C CA . ASP A 1 316 ? 18.708 45.800 29.856 1.00 22.85 ? 316 ASP A CA 1 ATOM 2369 C C . ASP A 1 316 ? 18.456 46.577 28.580 1.00 21.37 ? 316 ASP A C 1 ATOM 2370 O O . ASP A 1 316 ? 18.216 45.993 27.523 1.00 19.96 ? 316 ASP A O 1 ATOM 2371 C CB . ASP A 1 316 ? 17.430 45.991 30.694 1.00 26.34 ? 316 ASP A CB 1 ATOM 2372 C CG . ASP A 1 316 ? 17.341 45.072 31.898 1.00 29.19 ? 316 ASP A CG 1 ATOM 2373 O OD1 . ASP A 1 316 ? 16.514 45.381 32.798 1.00 30.88 ? 316 ASP A OD1 1 ATOM 2374 O OD2 . ASP A 1 316 ? 18.062 44.052 31.943 1.00 31.73 ? 316 ASP A OD2 1 ATOM 2375 N N . LEU A 1 317 ? 18.459 47.903 28.699 1.00 20.56 ? 317 LEU A N 1 ATOM 2376 C CA . LEU A 1 317 ? 18.202 48.763 27.539 1.00 20.01 ? 317 LEU A CA 1 ATOM 2377 C C . LEU A 1 317 ? 19.260 48.619 26.454 1.00 18.15 ? 317 LEU A C 1 ATOM 2378 O O . LEU A 1 317 ? 18.935 48.463 25.278 1.00 18.08 ? 317 LEU A O 1 ATOM 2379 C CB . LEU A 1 317 ? 18.133 50.244 27.942 1.00 21.00 ? 317 LEU A CB 1 ATOM 2380 C CG . LEU A 1 317 ? 16.798 50.899 28.297 1.00 22.48 ? 317 LEU A CG 1 ATOM 2381 C CD1 . LEU A 1 317 ? 17.066 52.388 28.613 1.00 23.61 ? 317 LEU A CD1 1 ATOM 2382 C CD2 . LEU A 1 317 ? 15.794 50.781 27.144 1.00 21.97 ? 317 LEU A CD2 1 ATOM 2383 N N . LEU A 1 318 ? 20.517 48.657 26.871 1.00 16.98 ? 318 LEU A N 1 ATOM 2384 C CA . LEU A 1 318 ? 21.631 48.591 25.952 1.00 16.23 ? 318 LEU A CA 1 ATOM 2385 C C . LEU A 1 318 ? 21.711 47.256 25.266 1.00 16.40 ? 318 LEU A C 1 ATOM 2386 O O . LEU A 1 318 ? 21.825 47.197 24.042 1.00 15.82 ? 318 LEU A O 1 ATOM 2387 C CB . LEU A 1 318 ? 22.949 48.885 26.677 1.00 15.27 ? 318 LEU A CB 1 ATOM 2388 C CG . LEU A 1 318 ? 24.210 48.972 25.783 1.00 15.35 ? 318 LEU A CG 1 ATOM 2389 C CD1 . LEU A 1 318 ? 24.033 50.100 24.743 1.00 15.24 ? 318 LEU A CD1 1 ATOM 2390 C CD2 . LEU A 1 318 ? 25.442 49.242 26.648 1.00 13.79 ? 318 LEU A CD2 1 ATOM 2391 N N . VAL A 1 319 ? 21.653 46.177 26.034 1.00 15.25 ? 319 VAL A N 1 ATOM 2392 C CA . VAL A 1 319 ? 21.724 44.865 25.413 1.00 15.92 ? 319 VAL A CA 1 ATOM 2393 C C . VAL A 1 319 ? 20.575 44.687 24.409 1.00 16.28 ? 319 VAL A C 1 ATOM 2394 O O . VAL A 1 319 ? 20.751 44.050 23.367 1.00 16.92 ? 319 VAL A O 1 ATOM 2395 C CB . VAL A 1 319 ? 21.728 43.734 26.484 1.00 15.53 ? 319 VAL A CB 1 ATOM 2396 C CG1 . VAL A 1 319 ? 21.528 42.364 25.820 1.00 15.69 ? 319 VAL A CG1 1 ATOM 2397 C CG2 . VAL A 1 319 ? 23.069 43.766 27.258 1.00 16.36 ? 319 VAL A CG2 1 ATOM 2398 N N . ASP A 1 320 ? 19.411 45.279 24.673 1.00 16.38 ? 320 ASP A N 1 ATOM 2399 C CA . ASP A 1 320 ? 18.282 45.117 23.734 1.00 16.96 ? 320 ASP A CA 1 ATOM 2400 C C . ASP A 1 320 ? 18.576 45.840 22.400 1.00 16.49 ? 320 ASP A C 1 ATOM 2401 O O . ASP A 1 320 ? 18.238 45.339 21.319 1.00 15.77 ? 320 ASP A O 1 ATOM 2402 C CB . ASP A 1 320 ? 16.999 45.654 24.375 1.00 18.63 ? 320 ASP A CB 1 ATOM 2403 C CG . ASP A 1 320 ? 15.835 45.675 23.435 1.00 17.80 ? 320 ASP A CG 1 ATOM 2404 O OD1 . ASP A 1 320 ? 15.373 46.781 23.068 1.00 18.05 ? 320 ASP A OD1 1 ATOM 2405 O OD2 . ASP A 1 320 ? 15.371 44.581 23.080 1.00 20.42 ? 320 ASP A OD2 1 ATOM 2406 N N . GLN A 1 321 ? 19.187 47.023 22.481 1.00 14.62 ? 321 GLN A N 1 ATOM 2407 C CA . GLN A 1 321 ? 19.572 47.754 21.258 1.00 14.38 ? 321 GLN A CA 1 ATOM 2408 C C . GLN A 1 321 ? 20.591 46.906 20.486 1.00 14.36 ? 321 GLN A C 1 ATOM 2409 O O . GLN A 1 321 ? 20.476 46.726 19.261 1.00 13.40 ? 321 GLN A O 1 ATOM 2410 C CB . GLN A 1 321 ? 20.221 49.094 21.603 1.00 14.64 ? 321 GLN A CB 1 ATOM 2411 C CG . GLN A 1 321 ? 19.208 50.174 22.017 1.00 14.57 ? 321 GLN A CG 1 ATOM 2412 C CD . GLN A 1 321 ? 18.135 50.348 20.969 1.00 15.61 ? 321 GLN A CD 1 ATOM 2413 O OE1 . GLN A 1 321 ? 18.411 50.751 19.842 1.00 15.96 ? 321 GLN A OE1 1 ATOM 2414 N NE2 . GLN A 1 321 ? 16.894 50.023 21.332 1.00 16.02 ? 321 GLN A NE2 1 ATOM 2415 N N . TRP A 1 322 ? 21.580 46.375 21.210 1.00 13.32 ? 322 TRP A N 1 ATOM 2416 C CA . TRP A 1 322 ? 22.621 45.550 20.579 1.00 13.27 ? 322 TRP A CA 1 ATOM 2417 C C . TRP A 1 322 ? 22.022 44.340 19.862 1.00 13.42 ? 322 TRP A C 1 ATOM 2418 O O . TRP A 1 322 ? 22.384 44.034 18.722 1.00 13.92 ? 322 TRP A O 1 ATOM 2419 C CB . TRP A 1 322 ? 23.647 45.045 21.602 1.00 10.54 ? 322 TRP A CB 1 ATOM 2420 C CG . TRP A 1 322 ? 24.605 46.079 22.129 1.00 10.54 ? 322 TRP A CG 1 ATOM 2421 C CD1 . TRP A 1 322 ? 24.795 47.346 21.663 1.00 11.01 ? 322 TRP A CD1 1 ATOM 2422 C CD2 . TRP A 1 322 ? 25.507 45.916 23.222 1.00 10.33 ? 322 TRP A CD2 1 ATOM 2423 N NE1 . TRP A 1 322 ? 25.768 47.988 22.404 1.00 11.97 ? 322 TRP A NE1 1 ATOM 2424 C CE2 . TRP A 1 322 ? 26.222 47.129 23.366 1.00 10.76 ? 322 TRP A CE2 1 ATOM 2425 C CE3 . TRP A 1 322 ? 25.783 44.861 24.098 1.00 11.62 ? 322 TRP A CE3 1 ATOM 2426 C CZ2 . TRP A 1 322 ? 27.199 47.314 24.358 1.00 11.02 ? 322 TRP A CZ2 1 ATOM 2427 C CZ3 . TRP A 1 322 ? 26.757 45.037 25.091 1.00 9.86 ? 322 TRP A CZ3 1 ATOM 2428 C CH2 . TRP A 1 322 ? 27.452 46.250 25.215 1.00 12.34 ? 322 TRP A CH2 1 ATOM 2429 N N . LYS A 1 323 ? 21.112 43.647 20.530 1.00 13.21 ? 323 LYS A N 1 ATOM 2430 C CA . LYS A 1 323 ? 20.533 42.453 19.897 1.00 14.90 ? 323 LYS A CA 1 ATOM 2431 C C . LYS A 1 323 ? 19.691 42.811 18.692 1.00 13.90 ? 323 LYS A C 1 ATOM 2432 O O . LYS A 1 323 ? 19.620 42.044 17.750 1.00 14.35 ? 323 LYS A O 1 ATOM 2433 C CB . LYS A 1 323 ? 19.743 41.624 20.926 1.00 15.43 ? 323 LYS A CB 1 ATOM 2434 C CG . LYS A 1 323 ? 20.712 40.781 21.791 1.00 16.23 ? 323 LYS A CG 1 ATOM 2435 C CD . LYS A 1 323 ? 20.001 40.008 22.900 1.00 19.46 ? 323 LYS A CD 1 ATOM 2436 C CE . LYS A 1 323 ? 21.021 39.179 23.714 1.00 19.59 ? 323 LYS A CE 1 ATOM 2437 N NZ . LYS A 1 323 ? 20.305 38.289 24.661 1.00 23.98 ? 323 LYS A NZ 1 ATOM 2438 N N . LYS A 1 324 ? 19.049 43.971 18.718 1.00 13.69 ? 324 LYS A N 1 ATOM 2439 C CA . LYS A 1 324 ? 18.281 44.398 17.555 1.00 13.64 ? 324 LYS A CA 1 ATOM 2440 C C . LYS A 1 324 ? 19.268 44.671 16.412 1.00 12.94 ? 324 LYS A C 1 ATOM 2441 O O . LYS A 1 324 ? 19.072 44.199 15.297 1.00 14.17 ? 324 LYS A O 1 ATOM 2442 C CB . LYS A 1 324 ? 17.454 45.650 17.891 1.00 13.97 ? 324 LYS A CB 1 ATOM 2443 C CG . LYS A 1 324 ? 16.225 45.310 18.762 1.00 14.99 ? 324 LYS A CG 1 ATOM 2444 C CD . LYS A 1 324 ? 15.505 46.546 19.283 1.00 14.79 ? 324 LYS A CD 1 ATOM 2445 C CE . LYS A 1 324 ? 14.300 46.127 20.155 1.00 15.17 ? 324 LYS A CE 1 ATOM 2446 N NZ . LYS A 1 324 ? 13.608 47.308 20.756 1.00 16.23 ? 324 LYS A NZ 1 ATOM 2447 N N . LYS A 1 325 ? 20.340 45.417 16.690 1.00 11.70 ? 325 LYS A N 1 ATOM 2448 C CA . LYS A 1 325 ? 21.335 45.694 15.647 1.00 11.11 ? 325 LYS A CA 1 ATOM 2449 C C . LYS A 1 325 ? 21.893 44.368 15.106 1.00 11.90 ? 325 LYS A C 1 ATOM 2450 O O . LYS A 1 325 ? 22.103 44.224 13.893 1.00 10.69 ? 325 LYS A O 1 ATOM 2451 C CB . LYS A 1 325 ? 22.492 46.556 16.194 1.00 9.83 ? 325 LYS A CB 1 ATOM 2452 C CG . LYS A 1 325 ? 23.413 47.164 15.100 1.00 9.46 ? 325 LYS A CG 1 ATOM 2453 C CD . LYS A 1 325 ? 24.619 47.961 15.693 1.00 7.89 ? 325 LYS A CD 1 ATOM 2454 C CE . LYS A 1 325 ? 25.376 48.742 14.592 1.00 9.66 ? 325 LYS A CE 1 ATOM 2455 N NZ . LYS A 1 325 ? 26.588 49.392 15.137 1.00 9.35 ? 325 LYS A NZ 1 ATOM 2456 N N . ALA A 1 326 ? 22.122 43.398 15.995 1.00 11.88 ? 326 ALA A N 1 ATOM 2457 C CA . ALA A 1 326 ? 22.658 42.105 15.564 1.00 13.51 ? 326 ALA A CA 1 ATOM 2458 C C . ALA A 1 326 ? 21.743 41.360 14.571 1.00 12.89 ? 326 ALA A C 1 ATOM 2459 O O . ALA A 1 326 ? 22.206 40.551 13.780 1.00 14.46 ? 326 ALA A O 1 ATOM 2460 C CB . ALA A 1 326 ? 22.953 41.211 16.790 1.00 12.65 ? 326 ALA A CB 1 ATOM 2461 N N . GLU A 1 327 ? 20.444 41.620 14.602 1.00 14.55 ? 327 GLU A N 1 ATOM 2462 C CA . GLU A 1 327 ? 19.546 40.937 13.664 1.00 14.33 ? 327 GLU A CA 1 ATOM 2463 C C . GLU A 1 327 ? 19.808 41.298 12.209 1.00 13.98 ? 327 GLU A C 1 ATOM 2464 O O . GLU A 1 327 ? 19.371 40.583 11.306 1.00 13.85 ? 327 GLU A O 1 ATOM 2465 C CB . GLU A 1 327 ? 18.087 41.296 13.941 1.00 16.01 ? 327 GLU A CB 1 ATOM 2466 C CG . GLU A 1 327 ? 17.500 40.529 15.072 1.00 18.10 ? 327 GLU A CG 1 ATOM 2467 C CD . GLU A 1 327 ? 17.483 39.046 14.788 1.00 17.73 ? 327 GLU A CD 1 ATOM 2468 O OE1 . GLU A 1 327 ? 16.813 38.617 13.824 1.00 17.64 ? 327 GLU A OE1 1 ATOM 2469 O OE2 . GLU A 1 327 ? 18.158 38.326 15.531 1.00 19.21 ? 327 GLU A OE2 1 ATOM 2470 N N . LEU A 1 328 ? 20.483 42.423 11.982 1.00 13.04 ? 328 LEU A N 1 ATOM 2471 C CA . LEU A 1 328 ? 20.741 42.895 10.627 1.00 12.17 ? 328 LEU A CA 1 ATOM 2472 C C . LEU A 1 328 ? 21.971 42.261 10.004 1.00 12.80 ? 328 LEU A C 1 ATOM 2473 O O . LEU A 1 328 ? 22.263 42.498 8.816 1.00 12.98 ? 328 LEU A O 1 ATOM 2474 C CB . LEU A 1 328 ? 20.894 44.420 10.650 1.00 12.69 ? 328 LEU A CB 1 ATOM 2475 C CG . LEU A 1 328 ? 19.783 45.225 11.348 1.00 14.04 ? 328 LEU A CG 1 ATOM 2476 C CD1 . LEU A 1 328 ? 20.051 46.748 11.135 1.00 13.40 ? 328 LEU A CD1 1 ATOM 2477 C CD2 . LEU A 1 328 ? 18.378 44.858 10.767 1.00 14.48 ? 328 LEU A CD2 1 ATOM 2478 N N . TYR A 1 329 ? 22.698 41.462 10.788 1.00 11.95 ? 329 TYR A N 1 ATOM 2479 C CA . TYR A 1 329 ? 23.907 40.804 10.300 1.00 12.74 ? 329 TYR A CA 1 ATOM 2480 C C . TYR A 1 329 ? 23.841 39.297 10.466 1.00 13.38 ? 329 TYR A C 1 ATOM 2481 O O . TYR A 1 329 ? 22.954 38.793 11.154 1.00 14.03 ? 329 TYR A O 1 ATOM 2482 C CB . TYR A 1 329 ? 25.149 41.378 10.976 1.00 11.30 ? 329 TYR A CB 1 ATOM 2483 C CG . TYR A 1 329 ? 25.337 42.840 10.631 1.00 12.03 ? 329 TYR A CG 1 ATOM 2484 C CD1 . TYR A 1 329 ? 24.720 43.839 11.392 1.00 11.94 ? 329 TYR A CD1 1 ATOM 2485 C CD2 . TYR A 1 329 ? 26.096 43.218 9.521 1.00 10.81 ? 329 TYR A CD2 1 ATOM 2486 C CE1 . TYR A 1 329 ? 24.848 45.179 11.053 1.00 12.19 ? 329 TYR A CE1 1 ATOM 2487 C CE2 . TYR A 1 329 ? 26.237 44.541 9.168 1.00 11.33 ? 329 TYR A CE2 1 ATOM 2488 C CZ . TYR A 1 329 ? 25.605 45.518 9.937 1.00 12.29 ? 329 TYR A CZ 1 ATOM 2489 O OH . TYR A 1 329 ? 25.701 46.817 9.572 1.00 13.16 ? 329 TYR A OH 1 ATOM 2490 N N . ARG A 1 330 ? 24.781 38.591 9.837 1.00 12.84 ? 330 ARG A N 1 ATOM 2491 C CA . ARG A 1 330 ? 24.799 37.131 9.820 1.00 13.57 ? 330 ARG A CA 1 ATOM 2492 C C . ARG A 1 330 ? 25.615 36.355 10.850 1.00 14.12 ? 330 ARG A C 1 ATOM 2493 O O . ARG A 1 330 ? 25.392 35.161 11.016 1.00 12.99 ? 330 ARG A O 1 ATOM 2494 C CB . ARG A 1 330 ? 25.212 36.655 8.416 1.00 14.14 ? 330 ARG A CB 1 ATOM 2495 C CG . ARG A 1 330 ? 24.243 37.150 7.345 1.00 14.16 ? 330 ARG A CG 1 ATOM 2496 C CD . ARG A 1 330 ? 24.535 36.587 5.963 1.00 14.12 ? 330 ARG A CD 1 ATOM 2497 N NE . ARG A 1 330 ? 23.554 37.130 5.040 1.00 13.78 ? 330 ARG A NE 1 ATOM 2498 C CZ . ARG A 1 330 ? 23.293 36.616 3.841 1.00 15.62 ? 330 ARG A CZ 1 ATOM 2499 N NH1 . ARG A 1 330 ? 23.952 35.542 3.437 1.00 13.02 ? 330 ARG A NH1 1 ATOM 2500 N NH2 . ARG A 1 330 ? 22.359 37.172 3.057 1.00 13.26 ? 330 ARG A NH2 1 ATOM 2501 N N . THR A 1 331 ? 26.578 36.992 11.521 1.00 13.16 ? 331 THR A N 1 ATOM 2502 C CA . THR A 1 331 ? 27.357 36.244 12.510 1.00 11.94 ? 331 THR A CA 1 ATOM 2503 C C . THR A 1 331 ? 26.990 36.654 13.934 1.00 12.65 ? 331 THR A C 1 ATOM 2504 O O . THR A 1 331 ? 26.150 37.540 14.147 1.00 12.21 ? 331 THR A O 1 ATOM 2505 C CB . THR A 1 331 ? 28.862 36.473 12.324 1.00 12.57 ? 331 THR A CB 1 ATOM 2506 O OG1 . THR A 1 331 ? 29.195 37.781 12.784 1.00 10.29 ? 331 THR A OG1 1 ATOM 2507 C CG2 . THR A 1 331 ? 29.244 36.363 10.847 1.00 11.80 ? 331 THR A CG2 1 ATOM 2508 N N . ASN A 1 332 ? 27.631 36.023 14.915 1.00 12.80 ? 332 ASN A N 1 ATOM 2509 C CA . ASN A 1 332 ? 27.361 36.366 16.305 1.00 13.97 ? 332 ASN A CA 1 ATOM 2510 C C . ASN A 1 332 ? 28.396 37.368 16.829 1.00 13.62 ? 332 ASN A C 1 ATOM 2511 O O . ASN A 1 332 ? 28.569 37.519 18.046 1.00 12.29 ? 332 ASN A O 1 ATOM 2512 C CB . ASN A 1 332 ? 27.332 35.099 17.186 1.00 16.08 ? 332 ASN A CB 1 ATOM 2513 C CG . ASN A 1 332 ? 28.675 34.393 17.240 1.00 19.01 ? 332 ASN A CG 1 ATOM 2514 O OD1 . ASN A 1 332 ? 29.402 34.342 16.239 1.00 20.48 ? 332 ASN A OD1 1 ATOM 2515 N ND2 . ASN A 1 332 ? 29.015 33.844 18.405 1.00 19.25 ? 332 ASN A ND2 1 ATOM 2516 N N . VAL A 1 333 ? 29.058 38.079 15.905 1.00 12.36 ? 333 VAL A N 1 ATOM 2517 C CA . VAL A 1 333 ? 30.063 39.083 16.271 1.00 11.59 ? 333 VAL A CA 1 ATOM 2518 C C . VAL A 1 333 ? 29.498 40.460 15.860 1.00 13.19 ? 333 VAL A C 1 ATOM 2519 O O . VAL A 1 333 ? 29.233 40.722 14.666 1.00 13.25 ? 333 VAL A O 1 ATOM 2520 C CB . VAL A 1 333 ? 31.415 38.809 15.548 1.00 12.85 ? 333 VAL A CB 1 ATOM 2521 C CG1 . VAL A 1 333 ? 32.441 39.898 15.902 1.00 11.70 ? 333 VAL A CG1 1 ATOM 2522 C CG2 . VAL A 1 333 ? 31.944 37.426 15.945 1.00 11.78 ? 333 VAL A CG2 1 ATOM 2523 N N . LEU A 1 334 ? 29.344 41.341 16.845 1.00 10.54 ? 334 LEU A N 1 ATOM 2524 C CA . LEU A 1 334 ? 28.735 42.644 16.643 1.00 10.79 ? 334 LEU A CA 1 ATOM 2525 C C . LEU A 1 334 ? 29.677 43.842 16.765 1.00 9.74 ? 334 LEU A C 1 ATOM 2526 O O . LEU A 1 334 ? 30.412 43.961 17.741 1.00 10.58 ? 334 LEU A O 1 ATOM 2527 C CB . LEU A 1 334 ? 27.591 42.805 17.648 1.00 10.67 ? 334 LEU A CB 1 ATOM 2528 C CG . LEU A 1 334 ? 26.731 44.061 17.474 1.00 8.59 ? 334 LEU A CG 1 ATOM 2529 C CD1 . LEU A 1 334 ? 26.022 43.985 16.075 1.00 8.55 ? 334 LEU A CD1 1 ATOM 2530 C CD2 . LEU A 1 334 ? 25.704 44.124 18.586 1.00 8.62 ? 334 LEU A CD2 1 ATOM 2531 N N . LEU A 1 335 ? 29.645 44.734 15.782 1.00 9.94 ? 335 LEU A N 1 ATOM 2532 C CA . LEU A 1 335 ? 30.510 45.924 15.800 1.00 9.46 ? 335 LEU A CA 1 ATOM 2533 C C . LEU A 1 335 ? 29.724 47.102 16.336 1.00 9.56 ? 335 LEU A C 1 ATOM 2534 O O . LEU A 1 335 ? 28.661 47.426 15.806 1.00 9.36 ? 335 LEU A O 1 ATOM 2535 C CB . LEU A 1 335 ? 30.999 46.268 14.389 1.00 9.83 ? 335 LEU A CB 1 ATOM 2536 C CG . LEU A 1 335 ? 31.769 47.587 14.311 1.00 10.35 ? 335 LEU A CG 1 ATOM 2537 C CD1 . LEU A 1 335 ? 33.102 47.432 15.064 1.00 9.69 ? 335 LEU A CD1 1 ATOM 2538 C CD2 . LEU A 1 335 ? 32.040 47.938 12.842 1.00 11.75 ? 335 LEU A CD2 1 ATOM 2539 N N . ILE A 1 336 ? 30.246 47.735 17.388 1.00 9.92 ? 336 ILE A N 1 ATOM 2540 C CA . ILE A 1 336 ? 29.609 48.896 17.991 1.00 9.38 ? 336 ILE A CA 1 ATOM 2541 C C . ILE A 1 336 ? 30.630 50.052 18.036 1.00 9.88 ? 336 ILE A C 1 ATOM 2542 O O . ILE A 1 336 ? 31.430 50.145 18.962 1.00 10.87 ? 336 ILE A O 1 ATOM 2543 C CB . ILE A 1 336 ? 29.115 48.616 19.461 1.00 10.61 ? 336 ILE A CB 1 ATOM 2544 C CG1 . ILE A 1 336 ? 28.066 47.474 19.497 1.00 8.93 ? 336 ILE A CG1 1 ATOM 2545 C CG2 . ILE A 1 336 ? 28.497 49.921 20.061 1.00 8.78 ? 336 ILE A CG2 1 ATOM 2546 C CD1 . ILE A 1 336 ? 26.758 47.755 18.740 1.00 10.68 ? 336 ILE A CD1 1 ATOM 2547 N N . PRO A 1 337 ? 30.639 50.915 17.008 1.00 9.85 ? 337 PRO A N 1 ATOM 2548 C CA . PRO A 1 337 ? 31.572 52.042 17.005 1.00 9.58 ? 337 PRO A CA 1 ATOM 2549 C C . PRO A 1 337 ? 31.182 52.962 18.179 1.00 10.23 ? 337 PRO A C 1 ATOM 2550 O O . PRO A 1 337 ? 29.991 53.074 18.506 1.00 9.97 ? 337 PRO A O 1 ATOM 2551 C CB . PRO A 1 337 ? 31.293 52.735 15.674 1.00 9.14 ? 337 PRO A CB 1 ATOM 2552 C CG . PRO A 1 337 ? 30.711 51.642 14.794 1.00 9.94 ? 337 PRO A CG 1 ATOM 2553 C CD . PRO A 1 337 ? 29.861 50.850 15.753 1.00 8.61 ? 337 PRO A CD 1 ATOM 2554 N N . LEU A 1 338 ? 32.168 53.608 18.805 1.00 9.28 ? 338 LEU A N 1 ATOM 2555 C CA . LEU A 1 338 ? 31.871 54.520 19.918 1.00 10.32 ? 338 LEU A CA 1 ATOM 2556 C C . LEU A 1 338 ? 32.678 55.797 19.699 1.00 8.88 ? 338 LEU A C 1 ATOM 2557 O O . LEU A 1 338 ? 33.843 55.892 20.110 1.00 7.90 ? 338 LEU A O 1 ATOM 2558 C CB . LEU A 1 338 ? 32.251 53.899 21.268 1.00 10.43 ? 338 LEU A CB 1 ATOM 2559 C CG . LEU A 1 338 ? 31.931 54.778 22.472 1.00 11.94 ? 338 LEU A CG 1 ATOM 2560 C CD1 . LEU A 1 338 ? 30.450 54.755 22.782 1.00 10.95 ? 338 LEU A CD1 1 ATOM 2561 C CD2 . LEU A 1 338 ? 32.734 54.252 23.686 1.00 11.73 ? 338 LEU A CD2 1 ATOM 2562 N N . GLY A 1 339 ? 32.049 56.774 19.051 1.00 10.19 ? 339 GLY A N 1 ATOM 2563 C CA . GLY A 1 339 ? 32.742 58.031 18.784 1.00 10.97 ? 339 GLY A CA 1 ATOM 2564 C C . GLY A 1 339 ? 31.952 59.011 17.935 1.00 11.89 ? 339 GLY A C 1 ATOM 2565 O O . GLY A 1 339 ? 30.791 58.740 17.583 1.00 11.86 ? 339 GLY A O 1 ATOM 2566 N N . ASP A 1 340 ? 32.585 60.149 17.612 1.00 10.67 ? 340 ASP A N 1 ATOM 2567 C CA . ASP A 1 340 ? 31.969 61.205 16.831 1.00 10.17 ? 340 ASP A CA 1 ATOM 2568 C C . ASP A 1 340 ? 33.111 62.161 16.395 1.00 11.43 ? 340 ASP A C 1 ATOM 2569 O O . ASP A 1 340 ? 34.298 61.882 16.598 1.00 11.15 ? 340 ASP A O 1 ATOM 2570 C CB . ASP A 1 340 ? 30.974 61.941 17.729 1.00 11.26 ? 340 ASP A CB 1 ATOM 2571 C CG . ASP A 1 340 ? 29.815 62.591 16.966 1.00 13.47 ? 340 ASP A CG 1 ATOM 2572 O OD1 . ASP A 1 340 ? 29.995 62.924 15.761 1.00 12.49 ? 340 ASP A OD1 1 ATOM 2573 O OD2 . ASP A 1 340 ? 28.726 62.787 17.594 1.00 11.58 ? 340 ASP A OD2 1 ATOM 2574 N N . ASN A 1 341 ? 32.739 63.297 15.828 1.00 11.35 ? 341 ASN A N 1 ATOM 2575 C CA . ASN A 1 341 ? 33.700 64.280 15.337 1.00 11.63 ? 341 ASN A CA 1 ATOM 2576 C C . ASN A 1 341 ? 34.589 64.832 16.433 1.00 11.29 ? 341 ASN A C 1 ATOM 2577 O O . ASN A 1 341 ? 34.100 65.299 17.468 1.00 10.92 ? 341 ASN A O 1 ATOM 2578 C CB . ASN A 1 341 ? 32.962 65.450 14.661 1.00 11.32 ? 341 ASN A CB 1 ATOM 2579 C CG . ASN A 1 341 ? 32.252 65.037 13.378 1.00 12.39 ? 341 ASN A CG 1 ATOM 2580 O OD1 . ASN A 1 341 ? 32.313 63.878 12.943 1.00 12.04 ? 341 ASN A OD1 1 ATOM 2581 N ND2 . ASN A 1 341 ? 31.582 65.989 12.761 1.00 13.13 ? 341 ASN A ND2 1 ATOM 2582 N N . PHE A 1 342 ? 35.894 64.764 16.207 1.00 10.70 ? 342 PHE A N 1 ATOM 2583 C CA . PHE A 1 342 ? 36.858 65.291 17.153 1.00 10.69 ? 342 PHE A CA 1 ATOM 2584 C C . PHE A 1 342 ? 36.593 64.929 18.614 1.00 11.64 ? 342 PHE A C 1 ATOM 2585 O O . PHE A 1 342 ? 36.756 65.757 19.517 1.00 10.34 ? 342 PHE A O 1 ATOM 2586 C CB . PHE A 1 342 ? 36.962 66.811 16.987 1.00 9.99 ? 342 PHE A CB 1 ATOM 2587 C CG . PHE A 1 342 ? 37.550 67.239 15.640 1.00 10.48 ? 342 PHE A CG 1 ATOM 2588 C CD1 . PHE A 1 342 ? 36.728 67.682 14.615 1.00 10.18 ? 342 PHE A CD1 1 ATOM 2589 C CD2 . PHE A 1 342 ? 38.912 67.182 15.413 1.00 10.26 ? 342 PHE A CD2 1 ATOM 2590 C CE1 . PHE A 1 342 ? 37.254 68.064 13.386 1.00 9.08 ? 342 PHE A CE1 1 ATOM 2591 C CE2 . PHE A 1 342 ? 39.457 67.562 14.195 1.00 10.18 ? 342 PHE A CE2 1 ATOM 2592 C CZ . PHE A 1 342 ? 38.623 68.007 13.171 1.00 10.28 ? 342 PHE A CZ 1 ATOM 2593 N N . ARG A 1 343 ? 36.207 63.677 18.846 1.00 11.32 ? 343 ARG A N 1 ATOM 2594 C CA . ARG A 1 343 ? 35.981 63.200 20.201 1.00 12.31 ? 343 ARG A CA 1 ATOM 2595 C C . ARG A 1 343 ? 37.307 62.755 20.879 1.00 13.55 ? 343 ARG A C 1 ATOM 2596 O O . ARG A 1 343 ? 38.385 62.648 20.235 1.00 11.94 ? 343 ARG A O 1 ATOM 2597 C CB . ARG A 1 343 ? 34.992 62.012 20.190 1.00 12.28 ? 343 ARG A CB 1 ATOM 2598 C CG . ARG A 1 343 ? 33.531 62.414 19.994 1.00 12.29 ? 343 ARG A CG 1 ATOM 2599 C CD . ARG A 1 343 ? 33.127 63.373 21.085 1.00 13.61 ? 343 ARG A CD 1 ATOM 2600 N NE . ARG A 1 343 ? 31.701 63.696 21.033 1.00 13.09 ? 343 ARG A NE 1 ATOM 2601 C CZ . ARG A 1 343 ? 30.742 63.008 21.654 1.00 13.79 ? 343 ARG A CZ 1 ATOM 2602 N NH1 . ARG A 1 343 ? 31.022 61.923 22.403 1.00 12.96 ? 343 ARG A NH1 1 ATOM 2603 N NH2 . ARG A 1 343 ? 29.485 63.421 21.538 1.00 12.47 ? 343 ARG A NH2 1 ATOM 2604 N N . PHE A 1 344 ? 37.184 62.457 22.171 1.00 14.38 ? 344 PHE A N 1 ATOM 2605 C CA . PHE A 1 344 ? 38.283 62.011 23.011 1.00 14.44 ? 344 PHE A CA 1 ATOM 2606 C C . PHE A 1 344 ? 39.362 63.035 23.111 1.00 15.74 ? 344 PHE A C 1 ATOM 2607 O O . PHE A 1 344 ? 40.558 62.727 23.056 1.00 16.60 ? 344 PHE A O 1 ATOM 2608 C CB . PHE A 1 344 ? 38.819 60.689 22.518 1.00 13.12 ? 344 PHE A CB 1 ATOM 2609 C CG . PHE A 1 344 ? 37.835 59.589 22.689 1.00 14.49 ? 344 PHE A CG 1 ATOM 2610 C CD1 . PHE A 1 344 ? 37.016 59.209 21.641 1.00 12.23 ? 344 PHE A CD1 1 ATOM 2611 C CD2 . PHE A 1 344 ? 37.632 59.006 23.957 1.00 13.98 ? 344 PHE A CD2 1 ATOM 2612 C CE1 . PHE A 1 344 ? 36.013 58.279 21.834 1.00 15.37 ? 344 PHE A CE1 1 ATOM 2613 C CE2 . PHE A 1 344 ? 36.613 58.063 24.147 1.00 15.32 ? 344 PHE A CE2 1 ATOM 2614 C CZ . PHE A 1 344 ? 35.807 57.705 23.078 1.00 13.57 ? 344 PHE A CZ 1 ATOM 2615 N N . LYS A 1 345 ? 38.911 64.271 23.260 1.00 16.37 ? 345 LYS A N 1 ATOM 2616 C CA . LYS A 1 345 ? 39.809 65.389 23.377 1.00 18.39 ? 345 LYS A CA 1 ATOM 2617 C C . LYS A 1 345 ? 40.296 65.630 24.797 1.00 19.08 ? 345 LYS A C 1 ATOM 2618 O O . LYS A 1 345 ? 41.484 65.870 25.011 1.00 20.63 ? 345 LYS A O 1 ATOM 2619 C CB . LYS A 1 345 ? 39.138 66.646 22.870 1.00 18.38 ? 345 LYS A CB 1 ATOM 2620 C CG . LYS A 1 345 ? 40.007 67.837 23.007 1.00 20.23 ? 345 LYS A CG 1 ATOM 2621 C CD . LYS A 1 345 ? 39.292 69.035 22.429 1.00 21.74 ? 345 LYS A CD 1 ATOM 2622 C CE . LYS A 1 345 ? 40.028 70.302 22.773 1.00 22.41 ? 345 LYS A CE 1 ATOM 2623 N NZ . LYS A 1 345 ? 39.329 71.452 22.126 1.00 25.60 ? 345 LYS A NZ 1 ATOM 2624 N N . GLN A 1 346 ? 39.393 65.561 25.765 1.00 19.03 ? 346 GLN A N 1 ATOM 2625 C CA . GLN A 1 346 ? 39.768 65.820 27.148 1.00 19.95 ? 346 GLN A CA 1 ATOM 2626 C C . GLN A 1 346 ? 39.897 64.566 27.985 1.00 19.40 ? 346 GLN A C 1 ATOM 2627 O O . GLN A 1 346 ? 39.153 63.601 27.768 1.00 16.34 ? 346 GLN A O 1 ATOM 2628 C CB . GLN A 1 346 ? 38.720 66.717 27.780 1.00 22.72 ? 346 GLN A CB 1 ATOM 2629 C CG . GLN A 1 346 ? 38.706 68.082 27.180 1.00 27.54 ? 346 GLN A CG 1 ATOM 2630 C CD . GLN A 1 346 ? 37.560 68.886 27.702 1.00 31.11 ? 346 GLN A CD 1 ATOM 2631 O OE1 . GLN A 1 346 ? 36.437 68.790 27.191 1.00 32.63 ? 346 GLN A OE1 1 ATOM 2632 N NE2 . GLN A 1 346 ? 37.818 69.679 28.754 1.00 32.77 ? 346 GLN A NE2 1 ATOM 2633 N N . ASN A 1 347 ? 40.827 64.592 28.946 1.00 18.90 ? 347 ASN A N 1 ATOM 2634 C CA . ASN A 1 347 ? 41.021 63.450 29.839 1.00 21.24 ? 347 ASN A CA 1 ATOM 2635 C C . ASN A 1 347 ? 39.721 63.098 30.522 1.00 19.29 ? 347 ASN A C 1 ATOM 2636 O O . ASN A 1 347 ? 39.416 61.937 30.663 1.00 20.34 ? 347 ASN A O 1 ATOM 2637 C CB . ASN A 1 347 ? 42.079 63.744 30.908 1.00 25.23 ? 347 ASN A CB 1 ATOM 2638 C CG . ASN A 1 347 ? 43.379 64.145 30.298 1.00 29.91 ? 347 ASN A CG 1 ATOM 2639 O OD1 . ASN A 1 347 ? 43.704 65.347 30.210 1.00 34.33 ? 347 ASN A OD1 1 ATOM 2640 N ND2 . ASN A 1 347 ? 44.128 63.154 29.810 1.00 32.37 ? 347 ASN A ND2 1 ATOM 2641 N N . THR A 1 348 ? 38.952 64.097 30.940 1.00 17.19 ? 348 THR A N 1 ATOM 2642 C CA . THR A 1 348 ? 37.694 63.806 31.605 1.00 16.47 ? 348 THR A CA 1 ATOM 2643 C C . THR A 1 348 ? 36.723 63.093 30.652 1.00 15.56 ? 348 THR A C 1 ATOM 2644 O O . THR A 1 348 ? 35.842 62.340 31.084 1.00 14.28 ? 348 THR A O 1 ATOM 2645 C CB . THR A 1 348 ? 37.063 65.085 32.127 1.00 16.17 ? 348 THR A CB 1 ATOM 2646 O OG1 . THR A 1 348 ? 36.953 66.007 31.047 1.00 17.16 ? 348 THR A OG1 1 ATOM 2647 C CG2 . THR A 1 348 ? 37.945 65.713 33.249 1.00 18.57 ? 348 THR A CG2 1 ATOM 2648 N N . GLU A 1 349 ? 36.865 63.334 29.354 1.00 15.02 ? 349 GLU A N 1 ATOM 2649 C CA . GLU A 1 349 ? 36.003 62.636 28.388 1.00 14.31 ? 349 GLU A CA 1 ATOM 2650 C C . GLU A 1 349 ? 36.428 61.166 28.336 1.00 13.93 ? 349 GLU A C 1 ATOM 2651 O O . GLU A 1 349 ? 35.590 60.284 28.305 1.00 14.02 ? 349 GLU A O 1 ATOM 2652 C CB . GLU A 1 349 ? 36.134 63.211 26.983 1.00 14.04 ? 349 GLU A CB 1 ATOM 2653 C CG . GLU A 1 349 ? 35.288 62.430 25.944 1.00 13.35 ? 349 GLU A CG 1 ATOM 2654 C CD . GLU A 1 349 ? 35.352 63.055 24.556 1.00 13.05 ? 349 GLU A CD 1 ATOM 2655 O OE1 . GLU A 1 349 ? 34.799 62.478 23.613 1.00 14.24 ? 349 GLU A OE1 1 ATOM 2656 O OE2 . GLU A 1 349 ? 35.956 64.129 24.410 1.00 14.37 ? 349 GLU A OE2 1 ATOM 2657 N N . TRP A 1 350 ? 37.734 60.909 28.294 1.00 12.76 ? 350 TRP A N 1 ATOM 2658 C CA . TRP A 1 350 ? 38.217 59.531 28.261 1.00 13.25 ? 350 TRP A CA 1 ATOM 2659 C C . TRP A 1 350 ? 37.698 58.755 29.469 1.00 13.82 ? 350 TRP A C 1 ATOM 2660 O O . TRP A 1 350 ? 37.234 57.623 29.359 1.00 11.62 ? 350 TRP A O 1 ATOM 2661 C CB . TRP A 1 350 ? 39.750 59.492 28.266 1.00 13.32 ? 350 TRP A CB 1 ATOM 2662 C CG . TRP A 1 350 ? 40.358 59.759 26.917 1.00 12.41 ? 350 TRP A CG 1 ATOM 2663 C CD1 . TRP A 1 350 ? 40.728 60.976 26.387 1.00 12.10 ? 350 TRP A CD1 1 ATOM 2664 C CD2 . TRP A 1 350 ? 40.636 58.784 25.912 1.00 12.81 ? 350 TRP A CD2 1 ATOM 2665 N NE1 . TRP A 1 350 ? 41.215 60.801 25.120 1.00 11.50 ? 350 TRP A NE1 1 ATOM 2666 C CE2 . TRP A 1 350 ? 41.173 59.465 24.805 1.00 11.45 ? 350 TRP A CE2 1 ATOM 2667 C CE3 . TRP A 1 350 ? 40.480 57.385 25.837 1.00 12.32 ? 350 TRP A CE3 1 ATOM 2668 C CZ2 . TRP A 1 350 ? 41.558 58.798 23.639 1.00 12.34 ? 350 TRP A CZ2 1 ATOM 2669 C CZ3 . TRP A 1 350 ? 40.863 56.729 24.673 1.00 12.41 ? 350 TRP A CZ3 1 ATOM 2670 C CH2 . TRP A 1 350 ? 41.397 57.440 23.590 1.00 10.55 ? 350 TRP A CH2 1 ATOM 2671 N N . ASP A 1 351 ? 37.792 59.377 30.636 1.00 14.64 ? 351 ASP A N 1 ATOM 2672 C CA . ASP A 1 351 ? 37.327 58.748 31.855 1.00 16.54 ? 351 ASP A CA 1 ATOM 2673 C C . ASP A 1 351 ? 35.817 58.460 31.860 1.00 16.67 ? 351 ASP A C 1 ATOM 2674 O O . ASP A 1 351 ? 35.373 57.337 32.163 1.00 16.98 ? 351 ASP A O 1 ATOM 2675 C CB . ASP A 1 351 ? 37.644 59.651 33.044 1.00 17.92 ? 351 ASP A CB 1 ATOM 2676 C CG . ASP A 1 351 ? 39.102 59.628 33.423 1.00 20.51 ? 351 ASP A CG 1 ATOM 2677 O OD1 . ASP A 1 351 ? 39.794 58.605 33.212 1.00 21.94 ? 351 ASP A OD1 1 ATOM 2678 O OD2 . ASP A 1 351 ? 39.552 60.633 33.975 1.00 24.25 ? 351 ASP A OD2 1 ATOM 2679 N N . VAL A 1 352 ? 35.032 59.472 31.521 1.00 16.13 ? 352 VAL A N 1 ATOM 2680 C CA . VAL A 1 352 ? 33.597 59.295 31.575 1.00 16.67 ? 352 VAL A CA 1 ATOM 2681 C C . VAL A 1 352 ? 33.119 58.198 30.619 1.00 15.89 ? 352 VAL A C 1 ATOM 2682 O O . VAL A 1 352 ? 32.247 57.408 30.975 1.00 15.40 ? 352 VAL A O 1 ATOM 2683 C CB . VAL A 1 352 ? 32.852 60.656 31.357 1.00 17.84 ? 352 VAL A CB 1 ATOM 2684 C CG1 . VAL A 1 352 ? 32.714 60.992 29.866 1.00 17.19 ? 352 VAL A CG1 1 ATOM 2685 C CG2 . VAL A 1 352 ? 31.516 60.613 32.060 1.00 17.99 ? 352 VAL A CG2 1 ATOM 2686 N N . GLN A 1 353 ? 33.692 58.125 29.419 1.00 14.58 ? 353 GLN A N 1 ATOM 2687 C CA . GLN A 1 353 ? 33.281 57.064 28.517 1.00 13.30 ? 353 GLN A CA 1 ATOM 2688 C C . GLN A 1 353 ? 33.824 55.703 29.012 1.00 13.39 ? 353 GLN A C 1 ATOM 2689 O O . GLN A 1 353 ? 33.075 54.741 29.130 1.00 14.14 ? 353 GLN A O 1 ATOM 2690 C CB . GLN A 1 353 ? 33.763 57.345 27.081 1.00 12.49 ? 353 GLN A CB 1 ATOM 2691 C CG . GLN A 1 353 ? 33.211 58.647 26.452 1.00 12.73 ? 353 GLN A CG 1 ATOM 2692 C CD . GLN A 1 353 ? 31.739 58.554 26.031 1.00 13.93 ? 353 GLN A CD 1 ATOM 2693 O OE1 . GLN A 1 353 ? 30.931 57.883 26.679 1.00 13.04 ? 353 GLN A OE1 1 ATOM 2694 N NE2 . GLN A 1 353 ? 31.382 59.267 24.952 1.00 12.87 ? 353 GLN A NE2 1 ATOM 2695 N N . ARG A 1 354 ? 35.118 55.622 29.317 1.00 12.58 ? 354 ARG A N 1 ATOM 2696 C CA . ARG A 1 354 ? 35.685 54.359 29.753 1.00 13.10 ? 354 ARG A CA 1 ATOM 2697 C C . ARG A 1 354 ? 35.071 53.749 31.020 1.00 13.81 ? 354 ARG A C 1 ATOM 2698 O O . ARG A 1 354 ? 34.732 52.564 31.035 1.00 13.45 ? 354 ARG A O 1 ATOM 2699 C CB . ARG A 1 354 ? 37.193 54.474 29.968 1.00 13.75 ? 354 ARG A CB 1 ATOM 2700 C CG . ARG A 1 354 ? 37.808 53.185 30.550 1.00 14.30 ? 354 ARG A CG 1 ATOM 2701 C CD . ARG A 1 354 ? 39.326 53.301 30.714 1.00 15.04 ? 354 ARG A CD 1 ATOM 2702 N NE . ARG A 1 354 ? 39.670 54.343 31.684 1.00 16.34 ? 354 ARG A NE 1 ATOM 2703 C CZ . ARG A 1 354 ? 39.519 54.239 33.004 1.00 16.44 ? 354 ARG A CZ 1 ATOM 2704 N NH1 . ARG A 1 354 ? 39.028 53.138 33.545 1.00 15.53 ? 354 ARG A NH1 1 ATOM 2705 N NH2 . ARG A 1 354 ? 39.865 55.243 33.785 1.00 15.36 ? 354 ARG A NH2 1 ATOM 2706 N N . VAL A 1 355 ? 34.931 54.552 32.067 1.00 14.12 ? 355 VAL A N 1 ATOM 2707 C CA . VAL A 1 355 ? 34.428 54.044 33.332 1.00 15.68 ? 355 VAL A CA 1 ATOM 2708 C C . VAL A 1 355 ? 33.000 53.517 33.241 1.00 16.91 ? 355 VAL A C 1 ATOM 2709 O O . VAL A 1 355 ? 32.708 52.395 33.692 1.00 17.32 ? 355 VAL A O 1 ATOM 2710 C CB . VAL A 1 355 ? 34.561 55.143 34.431 1.00 17.43 ? 355 VAL A CB 1 ATOM 2711 C CG1 . VAL A 1 355 ? 33.913 54.679 35.736 1.00 19.78 ? 355 VAL A CG1 1 ATOM 2712 C CG2 . VAL A 1 355 ? 36.070 55.424 34.696 1.00 16.77 ? 355 VAL A CG2 1 ATOM 2713 N N . ASN A 1 356 ? 32.110 54.309 32.652 1.00 14.92 ? 356 ASN A N 1 ATOM 2714 C CA . ASN A 1 356 ? 30.741 53.869 32.529 1.00 14.40 ? 356 ASN A CA 1 ATOM 2715 C C . ASN A 1 356 ? 30.632 52.592 31.699 1.00 15.06 ? 356 ASN A C 1 ATOM 2716 O O . ASN A 1 356 ? 29.921 51.664 32.103 1.00 13.66 ? 356 ASN A O 1 ATOM 2717 C CB . ASN A 1 356 ? 29.894 55.004 31.989 1.00 13.16 ? 356 ASN A CB 1 ATOM 2718 C CG . ASN A 1 356 ? 29.609 56.045 33.072 1.00 14.87 ? 356 ASN A CG 1 ATOM 2719 O OD1 . ASN A 1 356 ? 28.975 55.720 34.093 1.00 14.73 ? 356 ASN A OD1 1 ATOM 2720 N ND2 . ASN A 1 356 ? 30.116 57.273 32.892 1.00 11.80 ? 356 ASN A ND2 1 ATOM 2721 N N . TYR A 1 357 ? 31.366 52.510 30.581 1.00 13.77 ? 357 TYR A N 1 ATOM 2722 C CA . TYR A 1 357 ? 31.320 51.289 29.780 1.00 14.81 ? 357 TYR A CA 1 ATOM 2723 C C . TYR A 1 357 ? 31.928 50.094 30.513 1.00 15.19 ? 357 TYR A C 1 ATOM 2724 O O . TYR A 1 357 ? 31.447 48.961 30.384 1.00 16.76 ? 357 TYR A O 1 ATOM 2725 C CB . TYR A 1 357 ? 31.978 51.497 28.399 1.00 13.05 ? 357 TYR A CB 1 ATOM 2726 C CG . TYR A 1 357 ? 30.965 52.016 27.387 1.00 12.08 ? 357 TYR A CG 1 ATOM 2727 C CD1 . TYR A 1 357 ? 30.801 53.386 27.154 1.00 11.97 ? 357 TYR A CD1 1 ATOM 2728 C CD2 . TYR A 1 357 ? 30.142 51.126 26.694 1.00 10.87 ? 357 TYR A CD2 1 ATOM 2729 C CE1 . TYR A 1 357 ? 29.830 53.866 26.235 1.00 11.67 ? 357 TYR A CE1 1 ATOM 2730 C CE2 . TYR A 1 357 ? 29.175 51.579 25.784 1.00 12.07 ? 357 TYR A CE2 1 ATOM 2731 C CZ . TYR A 1 357 ? 29.016 52.946 25.556 1.00 13.52 ? 357 TYR A CZ 1 ATOM 2732 O OH . TYR A 1 357 ? 28.021 53.374 24.690 1.00 11.83 ? 357 TYR A OH 1 ATOM 2733 N N . GLU A 1 358 ? 32.974 50.319 31.294 1.00 15.37 ? 358 GLU A N 1 ATOM 2734 C CA . GLU A 1 358 ? 33.544 49.189 32.037 1.00 16.86 ? 358 GLU A CA 1 ATOM 2735 C C . GLU A 1 358 ? 32.488 48.656 33.023 1.00 16.19 ? 358 GLU A C 1 ATOM 2736 O O . GLU A 1 358 ? 32.367 47.443 33.215 1.00 15.97 ? 358 GLU A O 1 ATOM 2737 C CB . GLU A 1 358 ? 34.774 49.616 32.805 1.00 17.27 ? 358 GLU A CB 1 ATOM 2738 C CG . GLU A 1 358 ? 36.054 49.636 31.988 1.00 22.01 ? 358 GLU A CG 1 ATOM 2739 C CD . GLU A 1 358 ? 37.206 50.210 32.793 1.00 23.07 ? 358 GLU A CD 1 ATOM 2740 O OE1 . GLU A 1 358 ? 37.048 50.359 34.027 1.00 27.08 ? 358 GLU A OE1 1 ATOM 2741 O OE2 . GLU A 1 358 ? 38.263 50.528 32.218 1.00 26.50 ? 358 GLU A OE2 1 ATOM 2742 N N . ARG A 1 359 ? 31.725 49.555 33.646 1.00 15.69 ? 359 ARG A N 1 ATOM 2743 C CA . ARG A 1 359 ? 30.685 49.094 34.593 1.00 16.65 ? 359 ARG A CA 1 ATOM 2744 C C . ARG A 1 359 ? 29.644 48.247 33.861 1.00 16.07 ? 359 ARG A C 1 ATOM 2745 O O . ARG A 1 359 ? 29.206 47.216 34.381 1.00 15.34 ? 359 ARG A O 1 ATOM 2746 C CB . ARG A 1 359 ? 29.976 50.269 35.261 1.00 17.33 ? 359 ARG A CB 1 ATOM 2747 C CG . ARG A 1 359 ? 30.763 50.921 36.335 1.00 21.70 ? 359 ARG A CG 1 ATOM 2748 C CD . ARG A 1 359 ? 30.041 52.172 36.838 1.00 24.46 ? 359 ARG A CD 1 ATOM 2749 N NE . ARG A 1 359 ? 30.954 53.019 37.597 1.00 28.76 ? 359 ARG A NE 1 ATOM 2750 C CZ . ARG A 1 359 ? 31.071 54.342 37.438 1.00 31.49 ? 359 ARG A CZ 1 ATOM 2751 N NH1 . ARG A 1 359 ? 30.326 54.995 36.528 1.00 30.65 ? 359 ARG A NH1 1 ATOM 2752 N NH2 . ARG A 1 359 ? 31.931 55.016 38.209 1.00 32.06 ? 359 ARG A NH2 1 ATOM 2753 N N . LEU A 1 360 ? 29.249 48.691 32.662 1.00 13.77 ? 360 LEU A N 1 ATOM 2754 C CA . LEU A 1 360 ? 28.273 47.951 31.879 1.00 15.56 ? 360 LEU A CA 1 ATOM 2755 C C . LEU A 1 360 ? 28.829 46.595 31.480 1.00 15.69 ? 360 LEU A C 1 ATOM 2756 O O . LEU A 1 360 ? 28.151 45.577 31.612 1.00 17.40 ? 360 LEU A O 1 ATOM 2757 C CB . LEU A 1 360 ? 27.862 48.752 30.638 1.00 14.57 ? 360 LEU A CB 1 ATOM 2758 C CG . LEU A 1 360 ? 27.066 50.044 30.891 1.00 15.68 ? 360 LEU A CG 1 ATOM 2759 C CD1 . LEU A 1 360 ? 27.055 50.906 29.651 1.00 15.61 ? 360 LEU A CD1 1 ATOM 2760 C CD2 . LEU A 1 360 ? 25.626 49.717 31.314 1.00 13.81 ? 360 LEU A CD2 1 ATOM 2761 N N . PHE A 1 361 ? 30.068 46.558 30.999 1.00 15.91 ? 361 PHE A N 1 ATOM 2762 C CA . PHE A 1 361 ? 30.652 45.280 30.611 1.00 15.97 ? 361 PHE A CA 1 ATOM 2763 C C . PHE A 1 361 ? 30.742 44.318 31.815 1.00 16.85 ? 361 PHE A C 1 ATOM 2764 O O . PHE A 1 361 ? 30.456 43.118 31.693 1.00 15.31 ? 361 PHE A O 1 ATOM 2765 C CB . PHE A 1 361 ? 32.070 45.468 30.054 1.00 15.36 ? 361 PHE A CB 1 ATOM 2766 C CG . PHE A 1 361 ? 32.152 46.292 28.803 1.00 15.41 ? 361 PHE A CG 1 ATOM 2767 C CD1 . PHE A 1 361 ? 33.360 46.917 28.467 1.00 16.33 ? 361 PHE A CD1 1 ATOM 2768 C CD2 . PHE A 1 361 ? 31.065 46.438 27.958 1.00 14.18 ? 361 PHE A CD2 1 ATOM 2769 C CE1 . PHE A 1 361 ? 33.474 47.679 27.293 1.00 15.50 ? 361 PHE A CE1 1 ATOM 2770 C CE2 . PHE A 1 361 ? 31.161 47.186 26.799 1.00 14.91 ? 361 PHE A CE2 1 ATOM 2771 C CZ . PHE A 1 361 ? 32.368 47.810 26.461 1.00 16.38 ? 361 PHE A CZ 1 ATOM 2772 N N . GLU A 1 362 ? 31.160 44.828 32.975 1.00 16.68 ? 362 GLU A N 1 ATOM 2773 C CA . GLU A 1 362 ? 31.283 43.921 34.104 1.00 17.85 ? 362 GLU A CA 1 ATOM 2774 C C . GLU A 1 362 ? 29.933 43.267 34.432 1.00 16.36 ? 362 GLU A C 1 ATOM 2775 O O . GLU A 1 362 ? 29.858 42.059 34.620 1.00 16.02 ? 362 GLU A O 1 ATOM 2776 C CB . GLU A 1 362 ? 31.853 44.621 35.355 1.00 20.10 ? 362 GLU A CB 1 ATOM 2777 C CG . GLU A 1 362 ? 32.080 43.591 36.495 1.00 24.66 ? 362 GLU A CG 1 ATOM 2778 C CD . GLU A 1 362 ? 32.582 44.189 37.804 1.00 27.11 ? 362 GLU A CD 1 ATOM 2779 O OE1 . GLU A 1 362 ? 33.167 45.297 37.782 1.00 30.49 ? 362 GLU A OE1 1 ATOM 2780 O OE2 . GLU A 1 362 ? 32.399 43.524 38.859 1.00 29.32 ? 362 GLU A OE2 1 ATOM 2781 N N . HIS A 1 363 ? 28.870 44.059 34.488 1.00 15.66 ? 363 HIS A N 1 ATOM 2782 C CA . HIS A 1 363 ? 27.566 43.499 34.774 1.00 16.24 ? 363 HIS A CA 1 ATOM 2783 C C . HIS A 1 363 ? 27.079 42.561 33.644 1.00 16.13 ? 363 HIS A C 1 ATOM 2784 O O . HIS A 1 363 ? 26.724 41.394 33.872 1.00 15.17 ? 363 HIS A O 1 ATOM 2785 C CB . HIS A 1 363 ? 26.577 44.646 34.971 1.00 18.03 ? 363 HIS A CB 1 ATOM 2786 C CG . HIS A 1 363 ? 25.148 44.212 35.102 1.00 20.36 ? 363 HIS A CG 1 ATOM 2787 N ND1 . HIS A 1 363 ? 24.625 43.710 36.275 1.00 22.62 ? 363 HIS A ND1 1 ATOM 2788 C CD2 . HIS A 1 363 ? 24.128 44.229 34.212 1.00 20.50 ? 363 HIS A CD2 1 ATOM 2789 C CE1 . HIS A 1 363 ? 23.343 43.437 36.102 1.00 21.28 ? 363 HIS A CE1 1 ATOM 2790 N NE2 . HIS A 1 363 ? 23.017 43.744 34.857 1.00 21.11 ? 363 HIS A NE2 1 ATOM 2791 N N . ILE A 1 364 ? 27.053 43.073 32.422 1.00 14.94 ? 364 ILE A N 1 ATOM 2792 C CA . ILE A 1 364 ? 26.566 42.283 31.305 1.00 14.85 ? 364 ILE A CA 1 ATOM 2793 C C . ILE A 1 364 ? 27.263 40.939 31.132 1.00 15.75 ? 364 ILE A C 1 ATOM 2794 O O . ILE A 1 364 ? 26.593 39.904 30.989 1.00 16.01 ? 364 ILE A O 1 ATOM 2795 C CB . ILE A 1 364 ? 26.653 43.074 29.991 1.00 14.59 ? 364 ILE A CB 1 ATOM 2796 C CG1 . ILE A 1 364 ? 25.696 44.274 30.042 1.00 14.75 ? 364 ILE A CG1 1 ATOM 2797 C CG2 . ILE A 1 364 ? 26.322 42.137 28.798 1.00 12.97 ? 364 ILE A CG2 1 ATOM 2798 C CD1 . ILE A 1 364 ? 25.951 45.322 28.925 1.00 17.05 ? 364 ILE A CD1 1 ATOM 2799 N N . ASN A 1 365 ? 28.589 40.941 31.175 1.00 15.33 ? 365 ASN A N 1 ATOM 2800 C CA . ASN A 1 365 ? 29.353 39.711 30.985 1.00 17.34 ? 365 ASN A CA 1 ATOM 2801 C C . ASN A 1 365 ? 29.196 38.719 32.140 1.00 19.75 ? 365 ASN A C 1 ATOM 2802 O O . ASN A 1 365 ? 29.457 37.525 31.977 1.00 18.93 ? 365 ASN A O 1 ATOM 2803 C CB . ASN A 1 365 ? 30.836 40.028 30.775 1.00 15.32 ? 365 ASN A CB 1 ATOM 2804 C CG . ASN A 1 365 ? 31.077 40.928 29.553 1.00 16.05 ? 365 ASN A CG 1 ATOM 2805 O OD1 . ASN A 1 365 ? 30.170 41.164 28.751 1.00 14.21 ? 365 ASN A OD1 1 ATOM 2806 N ND2 . ASN A 1 365 ? 32.303 41.430 29.413 1.00 13.28 ? 365 ASN A ND2 1 ATOM 2807 N N . SER A 1 366 ? 28.750 39.201 33.302 1.00 22.04 ? 366 SER A N 1 ATOM 2808 C CA . SER A 1 366 ? 28.597 38.296 34.448 1.00 24.04 ? 366 SER A CA 1 ATOM 2809 C C . SER A 1 366 ? 27.149 37.843 34.607 1.00 24.85 ? 366 SER A C 1 ATOM 2810 O O . SER A 1 366 ? 26.856 37.044 35.465 1.00 26.41 ? 366 SER A O 1 ATOM 2811 C CB . SER A 1 366 ? 29.060 38.991 35.730 1.00 24.86 ? 366 SER A CB 1 ATOM 2812 O OG . SER A 1 366 ? 28.155 40.042 36.046 1.00 27.00 ? 366 SER A OG 1 ATOM 2813 N N . GLN A 1 367 ? 26.254 38.361 33.778 1.00 25.16 ? 367 GLN A N 1 ATOM 2814 C CA . GLN A 1 367 ? 24.841 38.006 33.804 1.00 26.34 ? 367 GLN A CA 1 ATOM 2815 C C . GLN A 1 367 ? 24.558 37.026 32.663 1.00 26.12 ? 367 GLN A C 1 ATOM 2816 O O . GLN A 1 367 ? 24.143 37.424 31.573 1.00 24.85 ? 367 GLN A O 1 ATOM 2817 C CB . GLN A 1 367 ? 23.960 39.255 33.626 1.00 26.77 ? 367 GLN A CB 1 ATOM 2818 C CG . GLN A 1 367 ? 24.058 40.258 34.770 1.00 30.24 ? 367 GLN A CG 1 ATOM 2819 C CD . GLN A 1 367 ? 23.675 39.634 36.113 1.00 32.85 ? 367 GLN A CD 1 ATOM 2820 O OE1 . GLN A 1 367 ? 22.522 39.229 36.319 1.00 32.44 ? 367 GLN A OE1 1 ATOM 2821 N NE2 . GLN A 1 367 ? 24.648 39.535 37.026 1.00 33.66 ? 367 GLN A NE2 1 ATOM 2822 N N . ALA A 1 368 ? 24.769 35.739 32.926 1.00 25.97 ? 368 ALA A N 1 ATOM 2823 C CA . ALA A 1 368 ? 24.550 34.711 31.916 1.00 25.38 ? 368 ALA A CA 1 ATOM 2824 C C . ALA A 1 368 ? 23.274 34.864 31.077 1.00 25.54 ? 368 ALA A C 1 ATOM 2825 O O . ALA A 1 368 ? 23.274 34.578 29.858 1.00 24.77 ? 368 ALA A O 1 ATOM 2826 C CB . ALA A 1 368 ? 24.565 33.335 32.575 1.00 25.18 ? 368 ALA A CB 1 ATOM 2827 N N . HIS A 1 369 ? 22.184 35.292 31.700 1.00 24.40 ? 369 HIS A N 1 ATOM 2828 C CA . HIS A 1 369 ? 20.943 35.417 30.941 1.00 24.21 ? 369 HIS A CA 1 ATOM 2829 C C . HIS A 1 369 ? 21.026 36.355 29.730 1.00 23.33 ? 369 HIS A C 1 ATOM 2830 O O . HIS A 1 369 ? 20.154 36.322 28.862 1.00 23.11 ? 369 HIS A O 1 ATOM 2831 C CB . HIS A 1 369 ? 19.802 35.853 31.853 1.00 25.31 ? 369 HIS A CB 1 ATOM 2832 C CG . HIS A 1 369 ? 19.866 37.291 32.275 1.00 27.68 ? 369 HIS A CG 1 ATOM 2833 N ND1 . HIS A 1 369 ? 19.339 38.316 31.514 1.00 26.98 ? 369 HIS A ND1 1 ATOM 2834 C CD2 . HIS A 1 369 ? 20.394 37.871 33.378 1.00 26.73 ? 369 HIS A CD2 1 ATOM 2835 C CE1 . HIS A 1 369 ? 19.540 39.466 32.133 1.00 27.02 ? 369 HIS A CE1 1 ATOM 2836 N NE2 . HIS A 1 369 ? 20.179 39.224 33.265 1.00 28.01 ? 369 HIS A NE2 1 ATOM 2837 N N . PHE A 1 370 ? 22.057 37.196 29.648 1.00 22.43 ? 370 PHE A N 1 ATOM 2838 C CA . PHE A 1 370 ? 22.150 38.079 28.468 1.00 20.03 ? 370 PHE A CA 1 ATOM 2839 C C . PHE A 1 370 ? 22.814 37.299 27.341 1.00 18.95 ? 370 PHE A C 1 ATOM 2840 O O . PHE A 1 370 ? 22.568 37.580 26.168 1.00 19.43 ? 370 PHE A O 1 ATOM 2841 C CB . PHE A 1 370 ? 23.024 39.312 28.743 1.00 20.44 ? 370 PHE A CB 1 ATOM 2842 C CG . PHE A 1 370 ? 22.321 40.424 29.502 1.00 19.60 ? 370 PHE A CG 1 ATOM 2843 C CD1 . PHE A 1 370 ? 22.850 40.906 30.691 1.00 19.40 ? 370 PHE A CD1 1 ATOM 2844 C CD2 . PHE A 1 370 ? 21.162 41.006 29.007 1.00 19.79 ? 370 PHE A CD2 1 ATOM 2845 C CE1 . PHE A 1 370 ? 22.231 41.965 31.385 1.00 16.98 ? 370 PHE A CE1 1 ATOM 2846 C CE2 . PHE A 1 370 ? 20.532 42.071 29.700 1.00 19.72 ? 370 PHE A CE2 1 ATOM 2847 C CZ . PHE A 1 370 ? 21.089 42.537 30.895 1.00 18.32 ? 370 PHE A CZ 1 ATOM 2848 N N . ASN A 1 371 ? 23.663 36.339 27.721 1.00 16.73 ? 371 ASN A N 1 ATOM 2849 C CA . ASN A 1 371 ? 24.455 35.533 26.787 1.00 16.12 ? 371 ASN A CA 1 ATOM 2850 C C . ASN A 1 371 ? 25.231 36.447 25.841 1.00 15.74 ? 371 ASN A C 1 ATOM 2851 O O . ASN A 1 371 ? 25.254 36.242 24.624 1.00 14.84 ? 371 ASN A O 1 ATOM 2852 C CB . ASN A 1 371 ? 23.566 34.587 26.002 1.00 16.93 ? 371 ASN A CB 1 ATOM 2853 C CG . ASN A 1 371 ? 22.964 33.518 26.893 1.00 17.07 ? 371 ASN A CG 1 ATOM 2854 O OD1 . ASN A 1 371 ? 23.686 32.703 27.474 1.00 16.01 ? 371 ASN A OD1 1 ATOM 2855 N ND2 . ASN A 1 371 ? 21.654 33.533 27.021 1.00 15.78 ? 371 ASN A ND2 1 ATOM 2856 N N . VAL A 1 372 ? 25.866 37.456 26.430 1.00 15.41 ? 372 VAL A N 1 ATOM 2857 C CA . VAL A 1 372 ? 26.668 38.451 25.701 1.00 15.16 ? 372 VAL A CA 1 ATOM 2858 C C . VAL A 1 372 ? 28.061 38.559 26.316 1.00 15.76 ? 372 VAL A C 1 ATOM 2859 O O . VAL A 1 372 ? 28.213 38.430 27.525 1.00 15.61 ? 372 VAL A O 1 ATOM 2860 C CB . VAL A 1 372 ? 26.046 39.867 25.825 1.00 15.63 ? 372 VAL A CB 1 ATOM 2861 C CG1 . VAL A 1 372 ? 27.043 40.927 25.290 1.00 14.05 ? 372 VAL A CG1 1 ATOM 2862 C CG2 . VAL A 1 372 ? 24.723 39.933 25.068 1.00 14.63 ? 372 VAL A CG2 1 ATOM 2863 N N . GLN A 1 373 ? 29.076 38.758 25.488 1.00 15.86 ? 373 GLN A N 1 ATOM 2864 C CA . GLN A 1 373 ? 30.440 38.981 25.997 1.00 17.01 ? 373 GLN A CA 1 ATOM 2865 C C . GLN A 1 373 ? 30.861 40.282 25.278 1.00 16.46 ? 373 GLN A C 1 ATOM 2866 O O . GLN A 1 373 ? 31.080 40.292 24.088 1.00 14.92 ? 373 GLN A O 1 ATOM 2867 C CB . GLN A 1 373 ? 31.398 37.822 25.644 1.00 17.33 ? 373 GLN A CB 1 ATOM 2868 C CG . GLN A 1 373 ? 32.879 38.116 25.996 1.00 17.79 ? 373 GLN A CG 1 ATOM 2869 C CD . GLN A 1 373 ? 33.140 38.479 27.492 1.00 19.76 ? 373 GLN A CD 1 ATOM 2870 O OE1 . GLN A 1 373 ? 34.034 39.278 27.805 1.00 19.85 ? 373 GLN A OE1 1 ATOM 2871 N NE2 . GLN A 1 373 ? 32.393 37.871 28.396 1.00 16.96 ? 373 GLN A NE2 1 ATOM 2872 N N . ALA A 1 374 ? 30.923 41.383 26.012 1.00 16.25 ? 374 ALA A N 1 ATOM 2873 C CA . ALA A 1 374 ? 31.248 42.663 25.427 1.00 15.84 ? 374 ALA A CA 1 ATOM 2874 C C . ALA A 1 374 ? 32.569 43.178 25.965 1.00 17.31 ? 374 ALA A C 1 ATOM 2875 O O . ALA A 1 374 ? 32.905 42.931 27.138 1.00 15.25 ? 374 ALA A O 1 ATOM 2876 C CB . ALA A 1 374 ? 30.157 43.657 25.754 1.00 15.41 ? 374 ALA A CB 1 ATOM 2877 N N . GLN A 1 375 ? 33.293 43.912 25.112 1.00 16.44 ? 375 GLN A N 1 ATOM 2878 C CA . GLN A 1 375 ? 34.575 44.497 25.492 1.00 17.40 ? 375 GLN A CA 1 ATOM 2879 C C . GLN A 1 375 ? 35.013 45.538 24.477 1.00 16.25 ? 375 GLN A C 1 ATOM 2880 O O . GLN A 1 375 ? 34.477 45.604 23.370 1.00 14.28 ? 375 GLN A O 1 ATOM 2881 C CB . GLN A 1 375 ? 35.680 43.433 25.573 1.00 19.97 ? 375 GLN A CB 1 ATOM 2882 C CG . GLN A 1 375 ? 35.958 42.715 24.266 1.00 24.66 ? 375 GLN A CG 1 ATOM 2883 C CD . GLN A 1 375 ? 35.057 41.513 24.087 1.00 29.10 ? 375 GLN A CD 1 ATOM 2884 O OE1 . GLN A 1 375 ? 34.053 41.547 23.341 1.00 31.79 ? 375 GLN A OE1 1 ATOM 2885 N NE2 . GLN A 1 375 ? 35.388 40.438 24.788 1.00 29.24 ? 375 GLN A NE2 1 ATOM 2886 N N . PHE A 1 376 ? 35.990 46.349 24.863 1.00 13.87 ? 376 PHE A N 1 ATOM 2887 C CA . PHE A 1 376 ? 36.520 47.331 23.943 1.00 13.58 ? 376 PHE A CA 1 ATOM 2888 C C . PHE A 1 376 ? 37.304 46.531 22.891 1.00 12.63 ? 376 PHE A C 1 ATOM 2889 O O . PHE A 1 376 ? 37.873 45.480 23.183 1.00 12.42 ? 376 PHE A O 1 ATOM 2890 C CB . PHE A 1 376 ? 37.456 48.310 24.674 1.00 12.68 ? 376 PHE A CB 1 ATOM 2891 C CG . PHE A 1 376 ? 36.739 49.237 25.616 1.00 13.43 ? 376 PHE A CG 1 ATOM 2892 C CD1 . PHE A 1 376 ? 37.106 49.314 26.951 1.00 13.13 ? 376 PHE A CD1 1 ATOM 2893 C CD2 . PHE A 1 376 ? 35.695 50.054 25.155 1.00 11.99 ? 376 PHE A CD2 1 ATOM 2894 C CE1 . PHE A 1 376 ? 36.463 50.186 27.828 1.00 11.69 ? 376 PHE A CE1 1 ATOM 2895 C CE2 . PHE A 1 376 ? 35.042 50.940 26.041 1.00 12.57 ? 376 PHE A CE2 1 ATOM 2896 C CZ . PHE A 1 376 ? 35.442 50.994 27.382 1.00 11.26 ? 376 PHE A CZ 1 ATOM 2897 N N . GLY A 1 377 ? 37.312 47.004 21.661 1.00 11.90 ? 377 GLY A N 1 ATOM 2898 C CA . GLY A 1 377 ? 38.069 46.281 20.640 1.00 11.33 ? 377 GLY A CA 1 ATOM 2899 C C . GLY A 1 377 ? 38.492 47.219 19.526 1.00 12.20 ? 377 GLY A C 1 ATOM 2900 O O . GLY A 1 377 ? 38.103 48.402 19.520 1.00 10.74 ? 377 GLY A O 1 ATOM 2901 N N . THR A 1 378 ? 39.294 46.704 18.592 1.00 11.30 ? 378 THR A N 1 ATOM 2902 C CA . THR A 1 378 ? 39.705 47.489 17.439 1.00 12.86 ? 378 THR A CA 1 ATOM 2903 C C . THR A 1 378 ? 38.923 46.963 16.228 1.00 11.23 ? 378 THR A C 1 ATOM 2904 O O . THR A 1 378 ? 38.203 45.951 16.305 1.00 10.78 ? 378 THR A O 1 ATOM 2905 C CB . THR A 1 378 ? 41.215 47.350 17.134 1.00 12.60 ? 378 THR A CB 1 ATOM 2906 O OG1 . THR A 1 378 ? 41.493 45.998 16.794 1.00 14.91 ? 378 THR A OG1 1 ATOM 2907 C CG2 . THR A 1 378 ? 42.045 47.729 18.351 1.00 14.17 ? 378 THR A CG2 1 ATOM 2908 N N . LEU A 1 379 ? 39.056 47.656 15.112 1.00 10.00 ? 379 LEU A N 1 ATOM 2909 C CA . LEU A 1 379 ? 38.368 47.263 13.894 1.00 9.76 ? 379 LEU A CA 1 ATOM 2910 C C . LEU A 1 379 ? 38.846 45.878 13.406 1.00 9.77 ? 379 LEU A C 1 ATOM 2911 O O . LEU A 1 379 ? 38.037 45.025 13.060 1.00 9.56 ? 379 LEU A O 1 ATOM 2912 C CB . LEU A 1 379 ? 38.631 48.329 12.832 1.00 10.11 ? 379 LEU A CB 1 ATOM 2913 C CG . LEU A 1 379 ? 37.870 48.088 11.535 1.00 11.16 ? 379 LEU A CG 1 ATOM 2914 C CD1 . LEU A 1 379 ? 36.363 48.120 11.840 1.00 8.50 ? 379 LEU A CD1 1 ATOM 2915 C CD2 . LEU A 1 379 ? 38.288 49.188 10.479 1.00 7.97 ? 379 LEU A CD2 1 ATOM 2916 N N . GLN A 1 380 ? 40.160 45.655 13.401 1.00 11.38 ? 380 GLN A N 1 ATOM 2917 C CA . GLN A 1 380 ? 40.717 44.369 12.945 1.00 13.49 ? 380 GLN A CA 1 ATOM 2918 C C . GLN A 1 380 ? 40.225 43.215 13.843 1.00 13.46 ? 380 GLN A C 1 ATOM 2919 O O . GLN A 1 380 ? 40.010 42.093 13.371 1.00 13.28 ? 380 GLN A O 1 ATOM 2920 C CB . GLN A 1 380 ? 42.244 44.412 12.965 1.00 15.51 ? 380 GLN A CB 1 ATOM 2921 C CG . GLN A 1 380 ? 42.910 43.185 12.391 1.00 20.47 ? 380 GLN A CG 1 ATOM 2922 C CD . GLN A 1 380 ? 42.561 42.969 10.927 1.00 25.46 ? 380 GLN A CD 1 ATOM 2923 O OE1 . GLN A 1 380 ? 42.643 43.902 10.104 1.00 26.61 ? 380 GLN A OE1 1 ATOM 2924 N NE2 . GLN A 1 380 ? 42.188 41.734 10.580 1.00 26.62 ? 380 GLN A NE2 1 ATOM 2925 N N . GLU A 1 381 ? 40.080 43.484 15.135 1.00 12.66 ? 381 GLU A N 1 ATOM 2926 C CA . GLU A 1 381 ? 39.593 42.447 16.040 1.00 13.98 ? 381 GLU A CA 1 ATOM 2927 C C . GLU A 1 381 ? 38.199 42.011 15.605 1.00 12.20 ? 381 GLU A C 1 ATOM 2928 O O . GLU A 1 381 ? 37.876 40.839 15.635 1.00 11.89 ? 381 GLU A O 1 ATOM 2929 C CB . GLU A 1 381 ? 39.489 42.956 17.462 1.00 15.58 ? 381 GLU A CB 1 ATOM 2930 C CG . GLU A 1 381 ? 40.774 42.932 18.261 1.00 20.27 ? 381 GLU A CG 1 ATOM 2931 C CD . GLU A 1 381 ? 40.491 43.326 19.700 1.00 22.19 ? 381 GLU A CD 1 ATOM 2932 O OE1 . GLU A 1 381 ? 40.610 44.509 20.017 1.00 19.79 ? 381 GLU A OE1 1 ATOM 2933 O OE2 . GLU A 1 381 ? 40.096 42.445 20.511 1.00 27.97 ? 381 GLU A OE2 1 ATOM 2934 N N . TYR A 1 382 ? 37.363 42.983 15.274 1.00 10.85 ? 382 TYR A N 1 ATOM 2935 C CA . TYR A 1 382 ? 36.022 42.704 14.820 1.00 10.60 ? 382 TYR A CA 1 ATOM 2936 C C . TYR A 1 382 ? 36.069 41.830 13.569 1.00 10.56 ? 382 TYR A C 1 ATOM 2937 O O . TYR A 1 382 ? 35.470 40.760 13.526 1.00 10.86 ? 382 TYR A O 1 ATOM 2938 C CB . TYR A 1 382 ? 35.289 44.001 14.479 1.00 10.67 ? 382 TYR A CB 1 ATOM 2939 C CG . TYR A 1 382 ? 33.960 43.734 13.803 1.00 12.57 ? 382 TYR A CG 1 ATOM 2940 C CD1 . TYR A 1 382 ? 32.900 43.139 14.508 1.00 12.09 ? 382 TYR A CD1 1 ATOM 2941 C CD2 . TYR A 1 382 ? 33.805 43.958 12.429 1.00 11.00 ? 382 TYR A CD2 1 ATOM 2942 C CE1 . TYR A 1 382 ? 31.726 42.771 13.863 1.00 12.50 ? 382 TYR A CE1 1 ATOM 2943 C CE2 . TYR A 1 382 ? 32.648 43.590 11.778 1.00 12.57 ? 382 TYR A CE2 1 ATOM 2944 C CZ . TYR A 1 382 ? 31.607 42.999 12.496 1.00 12.55 ? 382 TYR A CZ 1 ATOM 2945 O OH . TYR A 1 382 ? 30.448 42.655 11.845 1.00 13.90 ? 382 TYR A OH 1 ATOM 2946 N N . PHE A 1 383 ? 36.775 42.295 12.537 1.00 9.34 ? 383 PHE A N 1 ATOM 2947 C CA . PHE A 1 383 ? 36.853 41.529 11.299 1.00 9.20 ? 383 PHE A CA 1 ATOM 2948 C C . PHE A 1 383 ? 37.439 40.119 11.507 1.00 10.34 ? 383 PHE A C 1 ATOM 2949 O O . PHE A 1 383 ? 36.919 39.148 10.930 1.00 9.72 ? 383 PHE A O 1 ATOM 2950 C CB . PHE A 1 383 ? 37.656 42.304 10.259 1.00 9.58 ? 383 PHE A CB 1 ATOM 2951 C CG . PHE A 1 383 ? 36.869 43.435 9.603 1.00 8.73 ? 383 PHE A CG 1 ATOM 2952 C CD1 . PHE A 1 383 ? 37.349 44.726 9.637 1.00 10.03 ? 383 PHE A CD1 1 ATOM 2953 C CD2 . PHE A 1 383 ? 35.646 43.179 8.970 1.00 10.76 ? 383 PHE A CD2 1 ATOM 2954 C CE1 . PHE A 1 383 ? 36.634 45.768 9.055 1.00 10.61 ? 383 PHE A CE1 1 ATOM 2955 C CE2 . PHE A 1 383 ? 34.900 44.210 8.368 1.00 12.42 ? 383 PHE A CE2 1 ATOM 2956 C CZ . PHE A 1 383 ? 35.391 45.502 8.409 1.00 12.30 ? 383 PHE A CZ 1 ATOM 2957 N N . ASP A 1 384 ? 38.475 39.982 12.340 1.00 10.22 ? 384 ASP A N 1 ATOM 2958 C CA . ASP A 1 384 ? 39.051 38.642 12.555 1.00 11.92 ? 384 ASP A CA 1 ATOM 2959 C C . ASP A 1 384 ? 38.011 37.708 13.163 1.00 11.96 ? 384 ASP A C 1 ATOM 2960 O O . ASP A 1 384 ? 37.894 36.546 12.773 1.00 12.96 ? 384 ASP A O 1 ATOM 2961 C CB . ASP A 1 384 ? 40.255 38.678 13.505 1.00 14.34 ? 384 ASP A CB 1 ATOM 2962 C CG . ASP A 1 384 ? 41.451 39.358 12.905 1.00 15.12 ? 384 ASP A CG 1 ATOM 2963 O OD1 . ASP A 1 384 ? 41.544 39.462 11.658 1.00 15.73 ? 384 ASP A OD1 1 ATOM 2964 O OD2 . ASP A 1 384 ? 42.309 39.789 13.692 1.00 20.65 ? 384 ASP A OD2 1 ATOM 2965 N N . ALA A 1 385 ? 37.229 38.220 14.100 1.00 11.79 ? 385 ALA A N 1 ATOM 2966 C CA . ALA A 1 385 ? 36.229 37.387 14.757 1.00 12.57 ? 385 ALA A CA 1 ATOM 2967 C C . ALA A 1 385 ? 35.140 37.006 13.745 1.00 13.09 ? 385 ALA A C 1 ATOM 2968 O O . ALA A 1 385 ? 34.667 35.859 13.729 1.00 12.68 ? 385 ALA A O 1 ATOM 2969 C CB . ALA A 1 385 ? 35.619 38.143 15.979 1.00 11.68 ? 385 ALA A CB 1 ATOM 2970 N N . VAL A 1 386 ? 34.765 37.959 12.887 1.00 11.59 ? 386 VAL A N 1 ATOM 2971 C CA . VAL A 1 386 ? 33.745 37.700 11.874 1.00 12.01 ? 386 VAL A CA 1 ATOM 2972 C C . VAL A 1 386 ? 34.158 36.547 10.973 1.00 13.49 ? 386 VAL A C 1 ATOM 2973 O O . VAL A 1 386 ? 33.366 35.629 10.696 1.00 13.38 ? 386 VAL A O 1 ATOM 2974 C CB . VAL A 1 386 ? 33.514 38.938 10.976 1.00 11.96 ? 386 VAL A CB 1 ATOM 2975 C CG1 . VAL A 1 386 ? 32.714 38.562 9.726 1.00 11.19 ? 386 VAL A CG1 1 ATOM 2976 C CG2 . VAL A 1 386 ? 32.750 40.009 11.778 1.00 11.33 ? 386 VAL A CG2 1 ATOM 2977 N N . HIS A 1 387 ? 35.402 36.580 10.524 1.00 12.57 ? 387 HIS A N 1 ATOM 2978 C CA . HIS A 1 387 ? 35.877 35.549 9.618 1.00 13.74 ? 387 HIS A CA 1 ATOM 2979 C C . HIS A 1 387 ? 36.054 34.220 10.327 1.00 14.03 ? 387 HIS A C 1 ATOM 2980 O O . HIS A 1 387 ? 35.903 33.142 9.713 1.00 12.77 ? 387 HIS A O 1 ATOM 2981 C CB . HIS A 1 387 ? 37.150 36.033 8.903 1.00 13.83 ? 387 HIS A CB 1 ATOM 2982 C CG . HIS A 1 387 ? 36.884 37.162 7.951 1.00 16.27 ? 387 HIS A CG 1 ATOM 2983 N ND1 . HIS A 1 387 ? 36.030 37.034 6.873 1.00 15.74 ? 387 HIS A ND1 1 ATOM 2984 C CD2 . HIS A 1 387 ? 37.286 38.458 7.957 1.00 17.04 ? 387 HIS A CD2 1 ATOM 2985 C CE1 . HIS A 1 387 ? 35.912 38.202 6.261 1.00 16.98 ? 387 HIS A CE1 1 ATOM 2986 N NE2 . HIS A 1 387 ? 36.665 39.085 6.898 1.00 17.17 ? 387 HIS A NE2 1 ATOM 2987 N N . GLN A 1 388 ? 36.369 34.289 11.616 1.00 15.48 ? 388 GLN A N 1 ATOM 2988 C CA . GLN A 1 388 ? 36.475 33.065 12.397 1.00 18.17 ? 388 GLN A CA 1 ATOM 2989 C C . GLN A 1 388 ? 35.059 32.451 12.408 1.00 17.86 ? 388 GLN A C 1 ATOM 2990 O O . GLN A 1 388 ? 34.915 31.247 12.237 1.00 18.99 ? 388 GLN A O 1 ATOM 2991 C CB . GLN A 1 388 ? 36.948 33.352 13.823 1.00 20.86 ? 388 GLN A CB 1 ATOM 2992 C CG . GLN A 1 388 ? 38.445 33.690 13.907 1.00 26.70 ? 388 GLN A CG 1 ATOM 2993 C CD . GLN A 1 388 ? 38.843 34.392 15.225 1.00 30.92 ? 388 GLN A CD 1 ATOM 2994 O OE1 . GLN A 1 388 ? 38.017 34.552 16.140 1.00 34.91 ? 388 GLN A OE1 1 ATOM 2995 N NE2 . GLN A 1 388 ? 40.113 34.813 15.322 1.00 31.40 ? 388 GLN A NE2 1 ATOM 2996 N N . ALA A 1 389 ? 34.017 33.266 12.560 1.00 17.91 ? 389 ALA A N 1 ATOM 2997 C CA . ALA A 1 389 ? 32.648 32.723 12.578 1.00 19.10 ? 389 ALA A CA 1 ATOM 2998 C C . ALA A 1 389 ? 32.341 32.138 11.214 1.00 19.89 ? 389 ALA A C 1 ATOM 2999 O O . ALA A 1 389 ? 31.757 31.044 11.087 1.00 20.36 ? 389 ALA A O 1 ATOM 3000 C CB . ALA A 1 389 ? 31.629 33.810 12.950 1.00 17.96 ? 389 ALA A CB 1 ATOM 3001 N N . GLU A 1 390 ? 32.768 32.863 10.188 1.00 21.85 ? 390 GLU A N 1 ATOM 3002 C CA . GLU A 1 390 ? 32.597 32.447 8.803 1.00 22.72 ? 390 GLU A CA 1 ATOM 3003 C C . GLU A 1 390 ? 33.232 31.072 8.572 1.00 24.02 ? 390 GLU A C 1 ATOM 3004 O O . GLU A 1 390 ? 32.603 30.179 8.028 1.00 23.63 ? 390 GLU A O 1 ATOM 3005 C CB . GLU A 1 390 ? 33.267 33.459 7.873 1.00 23.23 ? 390 GLU A CB 1 ATOM 3006 C CG . GLU A 1 390 ? 33.200 33.077 6.395 1.00 22.55 ? 390 GLU A CG 1 ATOM 3007 C CD . GLU A 1 390 ? 33.855 34.111 5.484 1.00 22.86 ? 390 GLU A CD 1 ATOM 3008 O OE1 . GLU A 1 390 ? 34.697 34.917 5.955 1.00 21.67 ? 390 GLU A OE1 1 ATOM 3009 O OE2 . GLU A 1 390 ? 33.530 34.106 4.284 1.00 23.36 ? 390 GLU A OE2 1 ATOM 3010 N N . ARG A 1 391 ? 34.492 30.922 8.970 1.00 25.42 ? 391 ARG A N 1 ATOM 3011 C CA . ARG A 1 391 ? 35.194 29.661 8.804 1.00 26.60 ? 391 ARG A CA 1 ATOM 3012 C C . ARG A 1 391 ? 34.550 28.524 9.612 1.00 26.60 ? 391 ARG A C 1 ATOM 3013 O O . ARG A 1 391 ? 34.631 27.366 9.225 1.00 27.34 ? 391 ARG A O 1 ATOM 3014 C CB . ARG A 1 391 ? 36.678 29.812 9.198 1.00 28.04 ? 391 ARG A CB 1 ATOM 3015 C CG . ARG A 1 391 ? 37.523 30.557 8.144 1.00 29.43 ? 391 ARG A CG 1 ATOM 3016 C CD . ARG A 1 391 ? 39.020 30.406 8.390 1.00 30.36 ? 391 ARG A CD 1 ATOM 3017 N NE . ARG A 1 391 ? 39.459 31.027 9.636 1.00 32.14 ? 391 ARG A NE 1 ATOM 3018 C CZ . ARG A 1 391 ? 39.577 32.343 9.817 1.00 31.45 ? 391 ARG A CZ 1 ATOM 3019 N NH1 . ARG A 1 391 ? 39.287 33.186 8.828 1.00 31.43 ? 391 ARG A NH1 1 ATOM 3020 N NH2 . ARG A 1 391 ? 39.986 32.815 10.984 1.00 31.15 ? 391 ARG A NH2 1 ATOM 3021 N N . ALA A 1 392 ? 33.901 28.848 10.724 1.00 26.72 ? 392 ALA A N 1 ATOM 3022 C CA . ALA A 1 392 ? 33.270 27.820 11.546 1.00 27.25 ? 392 ALA A CA 1 ATOM 3023 C C . ALA A 1 392 ? 31.969 27.394 10.882 1.00 28.03 ? 392 ALA A C 1 ATOM 3024 O O . ALA A 1 392 ? 31.236 26.550 11.411 1.00 27.79 ? 392 ALA A O 1 ATOM 3025 C CB . ALA A 1 392 ? 32.991 28.340 12.945 1.00 26.94 ? 392 ALA A CB 1 ATOM 3026 N N . GLY A 1 393 ? 31.691 27.994 9.721 1.00 27.69 ? 393 GLY A N 1 ATOM 3027 C CA . GLY A 1 393 ? 30.490 27.659 8.994 1.00 27.18 ? 393 GLY A CA 1 ATOM 3028 C C . GLY A 1 393 ? 29.232 28.283 9.544 1.00 26.46 ? 393 GLY A C 1 ATOM 3029 O O . GLY A 1 393 ? 28.141 27.794 9.283 1.00 26.52 ? 393 GLY A O 1 ATOM 3030 N N . GLN A 1 394 ? 29.333 29.371 10.296 1.00 26.17 ? 394 GLN A N 1 ATOM 3031 C CA . GLN A 1 394 ? 28.083 29.919 10.773 1.00 26.74 ? 394 GLN A CA 1 ATOM 3032 C C . GLN A 1 394 ? 27.451 30.973 9.883 1.00 25.48 ? 394 GLN A C 1 ATOM 3033 O O . GLN A 1 394 ? 26.342 31.411 10.145 1.00 26.98 ? 394 GLN A O 1 ATOM 3034 C CB . GLN A 1 394 ? 28.199 30.399 12.227 1.00 28.56 ? 394 GLN A CB 1 ATOM 3035 C CG . GLN A 1 394 ? 29.089 31.562 12.499 1.00 31.55 ? 394 GLN A CG 1 ATOM 3036 C CD . GLN A 1 394 ? 28.749 32.226 13.841 1.00 32.05 ? 394 GLN A CD 1 ATOM 3037 O OE1 . GLN A 1 394 ? 27.959 33.183 13.902 1.00 31.26 ? 394 GLN A OE1 1 ATOM 3038 N NE2 . GLN A 1 394 ? 29.344 31.710 14.919 1.00 32.38 ? 394 GLN A NE2 1 ATOM 3039 N N . ALA A 1 395 ? 28.130 31.350 8.803 1.00 24.47 ? 395 ALA A N 1 ATOM 3040 C CA . ALA A 1 395 ? 27.609 32.333 7.874 1.00 23.05 ? 395 ALA A CA 1 ATOM 3041 C C . ALA A 1 395 ? 28.315 32.249 6.532 1.00 23.06 ? 395 ALA A C 1 ATOM 3042 O O . ALA A 1 395 ? 29.446 31.779 6.440 1.00 23.58 ? 395 ALA A O 1 ATOM 3043 C CB . ALA A 1 395 ? 27.770 33.746 8.454 1.00 24.14 ? 395 ALA A CB 1 ATOM 3044 N N . GLU A 1 396 ? 27.626 32.675 5.484 1.00 22.91 ? 396 GLU A N 1 ATOM 3045 C CA . GLU A 1 396 ? 28.196 32.731 4.133 1.00 23.85 ? 396 GLU A CA 1 ATOM 3046 C C . GLU A 1 396 ? 27.779 34.119 3.664 1.00 21.91 ? 396 GLU A C 1 ATOM 3047 O O . GLU A 1 396 ? 26.647 34.574 3.926 1.00 21.99 ? 396 GLU A O 1 ATOM 3048 C CB . GLU A 1 396 ? 27.590 31.662 3.231 1.00 28.01 ? 396 GLU A CB 1 ATOM 3049 C CG . GLU A 1 396 ? 26.094 31.837 2.987 1.00 34.14 ? 396 GLU A CG 1 ATOM 3050 C CD . GLU A 1 396 ? 25.466 30.594 2.351 1.00 38.19 ? 396 GLU A CD 1 ATOM 3051 O OE1 . GLU A 1 396 ? 26.055 30.047 1.383 1.00 40.41 ? 396 GLU A OE1 1 ATOM 3052 O OE2 . GLU A 1 396 ? 24.379 30.174 2.817 1.00 40.78 ? 396 GLU A OE2 1 ATOM 3053 N N . PHE A 1 397 ? 28.669 34.808 2.982 1.00 18.43 ? 397 PHE A N 1 ATOM 3054 C CA . PHE A 1 397 ? 28.344 36.160 2.584 1.00 15.40 ? 397 PHE A CA 1 ATOM 3055 C C . PHE A 1 397 ? 27.994 36.335 1.120 1.00 14.30 ? 397 PHE A C 1 ATOM 3056 O O . PHE A 1 397 ? 28.548 35.686 0.253 1.00 13.57 ? 397 PHE A O 1 ATOM 3057 C CB . PHE A 1 397 ? 29.489 37.102 2.958 1.00 14.25 ? 397 PHE A CB 1 ATOM 3058 C CG . PHE A 1 397 ? 29.766 37.154 4.442 1.00 14.32 ? 397 PHE A CG 1 ATOM 3059 C CD1 . PHE A 1 397 ? 30.864 36.475 4.991 1.00 13.45 ? 397 PHE A CD1 1 ATOM 3060 C CD2 . PHE A 1 397 ? 28.925 37.847 5.284 1.00 11.85 ? 397 PHE A CD2 1 ATOM 3061 C CE1 . PHE A 1 397 ? 31.106 36.497 6.381 1.00 13.37 ? 397 PHE A CE1 1 ATOM 3062 C CE2 . PHE A 1 397 ? 29.147 37.878 6.657 1.00 13.17 ? 397 PHE A CE2 1 ATOM 3063 C CZ . PHE A 1 397 ? 30.249 37.197 7.211 1.00 12.63 ? 397 PHE A CZ 1 ATOM 3064 N N . PRO A 1 398 ? 27.049 37.229 0.840 1.00 13.43 ? 398 PRO A N 1 ATOM 3065 C CA . PRO A 1 398 ? 26.616 37.504 -0.526 1.00 13.50 ? 398 PRO A CA 1 ATOM 3066 C C . PRO A 1 398 ? 27.707 38.270 -1.289 1.00 13.81 ? 398 PRO A C 1 ATOM 3067 O O . PRO A 1 398 ? 28.570 38.936 -0.673 1.00 14.66 ? 398 PRO A O 1 ATOM 3068 C CB . PRO A 1 398 ? 25.389 38.374 -0.307 1.00 12.17 ? 398 PRO A CB 1 ATOM 3069 C CG . PRO A 1 398 ? 25.792 39.150 0.924 1.00 13.88 ? 398 PRO A CG 1 ATOM 3070 C CD . PRO A 1 398 ? 26.311 38.063 1.801 1.00 13.21 ? 398 PRO A CD 1 ATOM 3071 N N . THR A 1 399 ? 27.661 38.181 -2.615 1.00 11.44 ? 399 THR A N 1 ATOM 3072 C CA . THR A 1 399 ? 28.593 38.908 -3.452 1.00 11.47 ? 399 THR A CA 1 ATOM 3073 C C . THR A 1 399 ? 27.855 40.167 -3.957 1.00 11.35 ? 399 THR A C 1 ATOM 3074 O O . THR A 1 399 ? 26.623 40.185 -4.070 1.00 11.19 ? 399 THR A O 1 ATOM 3075 C CB . THR A 1 399 ? 29.027 38.074 -4.665 1.00 11.94 ? 399 THR A CB 1 ATOM 3076 O OG1 . THR A 1 399 ? 27.859 37.645 -5.369 1.00 12.06 ? 399 THR A OG1 1 ATOM 3077 C CG2 . THR A 1 399 ? 29.860 36.861 -4.207 1.00 11.59 ? 399 THR A CG2 1 ATOM 3078 N N . LEU A 1 400 ? 28.610 41.208 -4.273 1.00 10.51 ? 400 LEU A N 1 ATOM 3079 C CA . LEU A 1 400 ? 28.005 42.459 -4.738 1.00 9.40 ? 400 LEU A CA 1 ATOM 3080 C C . LEU A 1 400 ? 28.936 43.204 -5.677 1.00 10.63 ? 400 LEU A C 1 ATOM 3081 O O . LEU A 1 400 ? 30.173 43.101 -5.533 1.00 10.69 ? 400 LEU A O 1 ATOM 3082 C CB . LEU A 1 400 ? 27.718 43.333 -3.528 1.00 9.42 ? 400 LEU A CB 1 ATOM 3083 C CG . LEU A 1 400 ? 26.980 44.668 -3.763 1.00 10.56 ? 400 LEU A CG 1 ATOM 3084 C CD1 . LEU A 1 400 ? 26.227 44.997 -2.510 1.00 9.69 ? 400 LEU A CD1 1 ATOM 3085 C CD2 . LEU A 1 400 ? 27.967 45.821 -4.122 1.00 11.95 ? 400 LEU A CD2 1 ATOM 3086 N N . SER A 1 401 ? 28.365 43.922 -6.652 1.00 10.64 ? 401 SER A N 1 ATOM 3087 C CA . SER A 1 401 ? 29.137 44.770 -7.564 1.00 9.27 ? 401 SER A CA 1 ATOM 3088 C C . SER A 1 401 ? 28.270 46.025 -7.732 1.00 10.08 ? 401 SER A C 1 ATOM 3089 O O . SER A 1 401 ? 27.072 45.971 -7.513 1.00 7.78 ? 401 SER A O 1 ATOM 3090 C CB . SER A 1 401 ? 29.402 44.098 -8.934 1.00 11.35 ? 401 SER A CB 1 ATOM 3091 O OG . SER A 1 401 ? 28.308 44.193 -9.827 1.00 9.80 ? 401 SER A OG 1 ATOM 3092 N N . GLY A 1 402 ? 28.891 47.150 -8.075 1.00 9.07 ? 402 GLY A N 1 ATOM 3093 C CA . GLY A 1 402 ? 28.162 48.388 -8.243 1.00 8.36 ? 402 GLY A CA 1 ATOM 3094 C C . GLY A 1 402 ? 28.781 49.478 -7.373 1.00 8.85 ? 402 GLY A C 1 ATOM 3095 O O . GLY A 1 402 ? 29.826 49.253 -6.756 1.00 6.91 ? 402 GLY A O 1 ATOM 3096 N N . ASP A 1 403 ? 28.161 50.659 -7.326 1.00 8.44 ? 403 ASP A N 1 ATOM 3097 C CA . ASP A 1 403 ? 28.688 51.740 -6.490 1.00 8.57 ? 403 ASP A CA 1 ATOM 3098 C C . ASP A 1 403 ? 27.577 52.232 -5.575 1.00 8.53 ? 403 ASP A C 1 ATOM 3099 O O . ASP A 1 403 ? 26.470 51.675 -5.584 1.00 7.31 ? 403 ASP A O 1 ATOM 3100 C CB . ASP A 1 403 ? 29.204 52.888 -7.356 1.00 8.78 ? 403 ASP A CB 1 ATOM 3101 C CG . ASP A 1 403 ? 28.090 53.640 -8.078 1.00 10.26 ? 403 ASP A CG 1 ATOM 3102 O OD1 . ASP A 1 403 ? 26.957 53.144 -8.187 1.00 12.58 ? 403 ASP A OD1 1 ATOM 3103 O OD2 . ASP A 1 403 ? 28.360 54.748 -8.566 1.00 10.71 ? 403 ASP A OD2 1 ATOM 3104 N N . PHE A 1 404 ? 27.874 53.254 -4.786 1.00 6.97 ? 404 PHE A N 1 ATOM 3105 C CA . PHE A 1 404 ? 26.918 53.816 -3.859 1.00 7.37 ? 404 PHE A CA 1 ATOM 3106 C C . PHE A 1 404 ? 26.784 55.310 -3.993 1.00 9.07 ? 404 PHE A C 1 ATOM 3107 O O . PHE A 1 404 ? 26.982 56.055 -3.017 1.00 6.70 ? 404 PHE A O 1 ATOM 3108 C CB . PHE A 1 404 ? 27.265 53.435 -2.407 1.00 7.57 ? 404 PHE A CB 1 ATOM 3109 C CG . PHE A 1 404 ? 27.194 51.941 -2.165 1.00 7.94 ? 404 PHE A CG 1 ATOM 3110 C CD1 . PHE A 1 404 ? 28.355 51.161 -2.176 1.00 6.35 ? 404 PHE A CD1 1 ATOM 3111 C CD2 . PHE A 1 404 ? 25.958 51.306 -2.033 1.00 7.40 ? 404 PHE A CD2 1 ATOM 3112 C CE1 . PHE A 1 404 ? 28.290 49.758 -2.058 1.00 9.69 ? 404 PHE A CE1 1 ATOM 3113 C CE2 . PHE A 1 404 ? 25.874 49.897 -1.914 1.00 7.90 ? 404 PHE A CE2 1 ATOM 3114 C CZ . PHE A 1 404 ? 27.037 49.122 -1.926 1.00 8.52 ? 404 PHE A CZ 1 ATOM 3115 N N . PHE A 1 405 ? 26.446 55.719 -5.224 1.00 9.44 ? 405 PHE A N 1 ATOM 3116 C CA . PHE A 1 405 ? 26.179 57.116 -5.564 1.00 10.52 ? 405 PHE A CA 1 ATOM 3117 C C . PHE A 1 405 ? 24.819 57.069 -6.259 1.00 10.78 ? 405 PHE A C 1 ATOM 3118 O O . PHE A 1 405 ? 24.533 56.097 -6.948 1.00 10.70 ? 405 PHE A O 1 ATOM 3119 C CB . PHE A 1 405 ? 27.238 57.649 -6.534 1.00 11.54 ? 405 PHE A CB 1 ATOM 3120 C CG . PHE A 1 405 ? 28.624 57.751 -5.933 1.00 12.78 ? 405 PHE A CG 1 ATOM 3121 C CD1 . PHE A 1 405 ? 29.689 57.034 -6.476 1.00 13.08 ? 405 PHE A CD1 1 ATOM 3122 C CD2 . PHE A 1 405 ? 28.868 58.593 -4.845 1.00 12.70 ? 405 PHE A CD2 1 ATOM 3123 C CE1 . PHE A 1 405 ? 30.973 57.153 -5.950 1.00 13.82 ? 405 PHE A CE1 1 ATOM 3124 C CE2 . PHE A 1 405 ? 30.159 58.725 -4.305 1.00 13.23 ? 405 PHE A CE2 1 ATOM 3125 C CZ . PHE A 1 405 ? 31.213 58.007 -4.852 1.00 13.39 ? 405 PHE A CZ 1 ATOM 3126 N N . THR A 1 406 ? 23.978 58.090 -6.124 1.00 10.30 ? 406 THR A N 1 ATOM 3127 C CA . THR A 1 406 ? 24.245 59.292 -5.368 1.00 10.84 ? 406 THR A CA 1 ATOM 3128 C C . THR A 1 406 ? 23.556 59.166 -4.015 1.00 11.57 ? 406 THR A C 1 ATOM 3129 O O . THR A 1 406 ? 22.378 58.776 -3.904 1.00 9.04 ? 406 THR A O 1 ATOM 3130 C CB . THR A 1 406 ? 23.725 60.558 -6.145 1.00 11.17 ? 406 THR A CB 1 ATOM 3131 O OG1 . THR A 1 406 ? 24.629 60.835 -7.228 1.00 12.01 ? 406 THR A OG1 1 ATOM 3132 C CG2 . THR A 1 406 ? 23.603 61.783 -5.239 1.00 9.90 ? 406 THR A CG2 1 ATOM 3133 N N . TYR A 1 407 ? 24.342 59.473 -2.994 1.00 10.72 ? 407 TYR A N 1 ATOM 3134 C CA . TYR A 1 407 ? 23.930 59.445 -1.613 1.00 10.92 ? 407 TYR A CA 1 ATOM 3135 C C . TYR A 1 407 ? 22.840 60.470 -1.231 1.00 11.84 ? 407 TYR A C 1 ATOM 3136 O O . TYR A 1 407 ? 22.835 61.612 -1.732 1.00 12.08 ? 407 TYR A O 1 ATOM 3137 C CB . TYR A 1 407 ? 25.174 59.705 -0.748 1.00 9.76 ? 407 TYR A CB 1 ATOM 3138 C CG . TYR A 1 407 ? 24.884 59.886 0.734 1.00 12.09 ? 407 TYR A CG 1 ATOM 3139 C CD1 . TYR A 1 407 ? 24.390 58.823 1.505 1.00 10.87 ? 407 TYR A CD1 1 ATOM 3140 C CD2 . TYR A 1 407 ? 25.212 61.073 1.381 1.00 11.10 ? 407 TYR A CD2 1 ATOM 3141 C CE1 . TYR A 1 407 ? 24.253 58.946 2.899 1.00 11.05 ? 407 TYR A CE1 1 ATOM 3142 C CE2 . TYR A 1 407 ? 25.088 61.200 2.757 1.00 9.97 ? 407 TYR A CE2 1 ATOM 3143 C CZ . TYR A 1 407 ? 24.619 60.131 3.517 1.00 10.02 ? 407 TYR A CZ 1 ATOM 3144 O OH . TYR A 1 407 ? 24.645 60.236 4.900 1.00 7.92 ? 407 TYR A OH 1 ATOM 3145 N N . ALA A 1 408 ? 21.931 60.040 -0.344 1.00 11.79 ? 408 ALA A N 1 ATOM 3146 C CA . ALA A 1 408 ? 20.895 60.900 0.238 1.00 12.66 ? 408 ALA A CA 1 ATOM 3147 C C . ALA A 1 408 ? 20.834 60.432 1.678 1.00 12.66 ? 408 ALA A C 1 ATOM 3148 O O . ALA A 1 408 ? 20.697 59.224 1.927 1.00 12.42 ? 408 ALA A O 1 ATOM 3149 C CB . ALA A 1 408 ? 19.504 60.708 -0.438 1.00 12.33 ? 408 ALA A CB 1 ATOM 3150 N N . ASP A 1 409 ? 20.962 61.354 2.634 1.00 12.97 ? 409 ASP A N 1 ATOM 3151 C CA . ASP A 1 409 ? 20.891 60.966 4.047 1.00 13.68 ? 409 ASP A CA 1 ATOM 3152 C C . ASP A 1 409 ? 19.451 61.033 4.575 1.00 14.29 ? 409 ASP A C 1 ATOM 3153 O O . ASP A 1 409 ? 19.133 60.431 5.598 1.00 14.21 ? 409 ASP A O 1 ATOM 3154 C CB . ASP A 1 409 ? 21.826 61.827 4.923 1.00 12.70 ? 409 ASP A CB 1 ATOM 3155 C CG . ASP A 1 409 ? 21.532 63.311 4.841 1.00 14.13 ? 409 ASP A CG 1 ATOM 3156 O OD1 . ASP A 1 409 ? 20.899 63.735 3.857 1.00 14.26 ? 409 ASP A OD1 1 ATOM 3157 O OD2 . ASP A 1 409 ? 21.956 64.074 5.761 1.00 14.06 ? 409 ASP A OD2 1 ATOM 3158 N N . ARG A 1 410 ? 18.578 61.756 3.875 1.00 14.02 ? 410 ARG A N 1 ATOM 3159 C CA . ARG A 1 410 ? 17.159 61.854 4.285 1.00 14.43 ? 410 ARG A CA 1 ATOM 3160 C C . ARG A 1 410 ? 16.324 62.458 3.166 1.00 15.32 ? 410 ARG A C 1 ATOM 3161 O O . ARG A 1 410 ? 16.851 63.202 2.329 1.00 15.07 ? 410 ARG A O 1 ATOM 3162 C CB . ARG A 1 410 ? 16.984 62.683 5.567 1.00 15.03 ? 410 ARG A CB 1 ATOM 3163 C CG . ARG A 1 410 ? 17.466 64.128 5.521 1.00 15.93 ? 410 ARG A CG 1 ATOM 3164 C CD . ARG A 1 410 ? 17.378 64.726 6.918 1.00 18.06 ? 410 ARG A CD 1 ATOM 3165 N NE . ARG A 1 410 ? 18.013 66.047 7.063 1.00 20.21 ? 410 ARG A NE 1 ATOM 3166 C CZ . ARG A 1 410 ? 17.454 67.216 6.726 1.00 21.75 ? 410 ARG A CZ 1 ATOM 3167 N NH1 . ARG A 1 410 ? 16.221 67.263 6.209 1.00 21.64 ? 410 ARG A NH1 1 ATOM 3168 N NH2 . ARG A 1 410 ? 18.130 68.345 6.914 1.00 18.91 ? 410 ARG A NH2 1 ATOM 3169 N N . SER A 1 411 ? 15.031 62.114 3.162 1.00 15.50 ? 411 SER A N 1 ATOM 3170 C CA . SER A 1 411 ? 14.051 62.560 2.165 1.00 15.27 ? 411 SER A CA 1 ATOM 3171 C C . SER A 1 411 ? 14.603 62.707 0.761 1.00 13.64 ? 411 SER A C 1 ATOM 3172 O O . SER A 1 411 ? 15.052 61.714 0.171 1.00 13.97 ? 411 SER A O 1 ATOM 3173 C CB . SER A 1 411 ? 13.346 63.868 2.604 1.00 17.48 ? 411 SER A CB 1 ATOM 3174 O OG . SER A 1 411 ? 14.263 64.899 2.891 1.00 22.47 ? 411 SER A OG 1 ATOM 3175 N N . ASP A 1 412 ? 14.562 63.921 0.209 1.00 12.12 ? 412 ASP A N 1 ATOM 3176 C CA . ASP A 1 412 ? 15.058 64.159 -1.159 1.00 12.26 ? 412 ASP A CA 1 ATOM 3177 C C . ASP A 1 412 ? 16.400 64.916 -1.123 1.00 11.65 ? 412 ASP A C 1 ATOM 3178 O O . ASP A 1 412 ? 16.814 65.479 -2.123 1.00 11.80 ? 412 ASP A O 1 ATOM 3179 C CB . ASP A 1 412 ? 14.048 65.015 -1.943 1.00 12.46 ? 412 ASP A CB 1 ATOM 3180 C CG . ASP A 1 412 ? 13.897 66.444 -1.347 1.00 13.80 ? 412 ASP A CG 1 ATOM 3181 O OD1 . ASP A 1 412 ? 14.397 66.690 -0.207 1.00 11.05 ? 412 ASP A OD1 1 ATOM 3182 O OD2 . ASP A 1 412 ? 13.286 67.309 -2.026 1.00 12.34 ? 412 ASP A OD2 1 ATOM 3183 N N . ASN A 1 413 ? 17.059 64.936 0.032 1.00 11.09 ? 413 ASN A N 1 ATOM 3184 C CA . ASN A 1 413 ? 18.333 65.654 0.178 1.00 10.97 ? 413 ASN A CA 1 ATOM 3185 C C . ASN A 1 413 ? 19.495 64.814 -0.400 1.00 11.29 ? 413 ASN A C 1 ATOM 3186 O O . ASN A 1 413 ? 20.208 64.121 0.343 1.00 10.32 ? 413 ASN A O 1 ATOM 3187 C CB . ASN A 1 413 ? 18.600 65.948 1.654 1.00 9.94 ? 413 ASN A CB 1 ATOM 3188 C CG . ASN A 1 413 ? 17.704 67.033 2.228 1.00 11.81 ? 413 ASN A CG 1 ATOM 3189 O OD1 . ASN A 1 413 ? 17.992 67.552 3.311 1.00 13.86 ? 413 ASN A OD1 1 ATOM 3190 N ND2 . ASN A 1 413 ? 16.610 67.377 1.529 1.00 9.72 ? 413 ASN A ND2 1 ATOM 3191 N N . TYR A 1 414 ? 19.653 64.867 -1.718 1.00 10.30 ? 414 TYR A N 1 ATOM 3192 C CA . TYR A 1 414 ? 20.703 64.130 -2.429 1.00 10.59 ? 414 TYR A CA 1 ATOM 3193 C C . TYR A 1 414 ? 21.965 65.005 -2.504 1.00 11.02 ? 414 TYR A C 1 ATOM 3194 O O . TYR A 1 414 ? 21.914 66.186 -2.894 1.00 11.29 ? 414 TYR A O 1 ATOM 3195 C CB . TYR A 1 414 ? 20.249 63.735 -3.845 1.00 9.56 ? 414 TYR A CB 1 ATOM 3196 C CG . TYR A 1 414 ? 19.261 62.568 -3.882 1.00 10.20 ? 414 TYR A CG 1 ATOM 3197 C CD1 . TYR A 1 414 ? 17.891 62.764 -3.644 1.00 10.78 ? 414 TYR A CD1 1 ATOM 3198 C CD2 . TYR A 1 414 ? 19.707 61.261 -4.130 1.00 10.59 ? 414 TYR A CD2 1 ATOM 3199 C CE1 . TYR A 1 414 ? 17.000 61.682 -3.649 1.00 10.84 ? 414 TYR A CE1 1 ATOM 3200 C CE2 . TYR A 1 414 ? 18.830 60.181 -4.143 1.00 9.16 ? 414 TYR A CE2 1 ATOM 3201 C CZ . TYR A 1 414 ? 17.479 60.398 -3.898 1.00 11.08 ? 414 TYR A CZ 1 ATOM 3202 O OH . TYR A 1 414 ? 16.624 59.319 -3.896 1.00 9.18 ? 414 TYR A OH 1 ATOM 3203 N N . TRP A 1 415 ? 23.091 64.391 -2.152 1.00 9.47 ? 415 TRP A N 1 ATOM 3204 C CA . TRP A 1 415 ? 24.371 65.090 -2.093 1.00 10.25 ? 415 TRP A CA 1 ATOM 3205 C C . TRP A 1 415 ? 25.112 65.112 -3.427 1.00 10.79 ? 415 TRP A C 1 ATOM 3206 O O . TRP A 1 415 ? 26.226 64.627 -3.505 1.00 11.60 ? 415 TRP A O 1 ATOM 3207 C CB . TRP A 1 415 ? 25.273 64.450 -1.027 1.00 9.54 ? 415 TRP A CB 1 ATOM 3208 C CG . TRP A 1 415 ? 24.731 64.516 0.404 1.00 9.13 ? 415 TRP A CG 1 ATOM 3209 C CD1 . TRP A 1 415 ? 23.445 64.307 0.802 1.00 8.64 ? 415 TRP A CD1 1 ATOM 3210 C CD2 . TRP A 1 415 ? 25.496 64.738 1.607 1.00 9.81 ? 415 TRP A CD2 1 ATOM 3211 N NE1 . TRP A 1 415 ? 23.355 64.374 2.170 1.00 10.85 ? 415 TRP A NE1 1 ATOM 3212 C CE2 . TRP A 1 415 ? 24.601 64.642 2.692 1.00 8.83 ? 415 TRP A CE2 1 ATOM 3213 C CE3 . TRP A 1 415 ? 26.858 65.011 1.868 1.00 8.28 ? 415 TRP A CE3 1 ATOM 3214 C CZ2 . TRP A 1 415 ? 25.014 64.807 4.030 1.00 9.77 ? 415 TRP A CZ2 1 ATOM 3215 C CZ3 . TRP A 1 415 ? 27.269 65.175 3.178 1.00 7.94 ? 415 TRP A CZ3 1 ATOM 3216 C CH2 . TRP A 1 415 ? 26.352 65.071 4.258 1.00 8.48 ? 415 TRP A CH2 1 ATOM 3217 N N . SER A 1 416 ? 24.499 65.693 -4.455 1.00 9.66 ? 416 SER A N 1 ATOM 3218 C CA . SER A 1 416 ? 25.164 65.781 -5.743 1.00 9.57 ? 416 SER A CA 1 ATOM 3219 C C . SER A 1 416 ? 25.747 67.194 -6.023 1.00 9.53 ? 416 SER A C 1 ATOM 3220 O O . SER A 1 416 ? 26.388 67.427 -7.067 1.00 9.40 ? 416 SER A O 1 ATOM 3221 C CB . SER A 1 416 ? 24.204 65.353 -6.852 1.00 9.27 ? 416 SER A CB 1 ATOM 3222 O OG . SER A 1 416 ? 22.938 65.961 -6.731 1.00 11.13 ? 416 SER A OG 1 ATOM 3223 N N . GLY A 1 417 ? 25.522 68.139 -5.108 1.00 9.99 ? 417 GLY A N 1 ATOM 3224 C CA . GLY A 1 417 ? 26.084 69.475 -5.294 1.00 9.87 ? 417 GLY A CA 1 ATOM 3225 C C . GLY A 1 417 ? 27.616 69.490 -5.210 1.00 9.61 ? 417 GLY A C 1 ATOM 3226 O O . GLY A 1 417 ? 28.303 70.182 -5.978 1.00 8.20 ? 417 GLY A O 1 ATOM 3227 N N . TYR A 1 418 ? 28.166 68.701 -4.289 1.00 9.97 ? 418 TYR A N 1 ATOM 3228 C CA . TYR A 1 418 ? 29.604 68.667 -4.095 1.00 9.14 ? 418 TYR A CA 1 ATOM 3229 C C . TYR A 1 418 ? 30.354 68.047 -5.299 1.00 8.52 ? 418 TYR A C 1 ATOM 3230 O O . TYR A 1 418 ? 31.573 68.058 -5.333 1.00 7.78 ? 418 TYR A O 1 ATOM 3231 C CB . TYR A 1 418 ? 29.957 67.944 -2.786 1.00 9.85 ? 418 TYR A CB 1 ATOM 3232 C CG . TYR A 1 418 ? 30.126 66.424 -2.884 1.00 10.79 ? 418 TYR A CG 1 ATOM 3233 C CD1 . TYR A 1 418 ? 31.396 65.848 -3.034 1.00 10.56 ? 418 TYR A CD1 1 ATOM 3234 C CD2 . TYR A 1 418 ? 29.032 65.566 -2.756 1.00 11.99 ? 418 TYR A CD2 1 ATOM 3235 C CE1 . TYR A 1 418 ? 31.559 64.450 -3.049 1.00 9.37 ? 418 TYR A CE1 1 ATOM 3236 C CE2 . TYR A 1 418 ? 29.188 64.146 -2.771 1.00 10.46 ? 418 TYR A CE2 1 ATOM 3237 C CZ . TYR A 1 418 ? 30.454 63.614 -2.918 1.00 9.13 ? 418 TYR A CZ 1 ATOM 3238 O OH . TYR A 1 418 ? 30.608 62.237 -2.904 1.00 10.55 ? 418 TYR A OH 1 ATOM 3239 N N . TYR A 1 419 ? 29.626 67.507 -6.278 1.00 8.61 ? 419 TYR A N 1 ATOM 3240 C CA . TYR A 1 419 ? 30.294 66.981 -7.471 1.00 7.99 ? 419 TYR A CA 1 ATOM 3241 C C . TYR A 1 419 ? 30.804 68.201 -8.273 1.00 8.49 ? 419 TYR A C 1 ATOM 3242 O O . TYR A 1 419 ? 31.619 68.057 -9.198 1.00 9.20 ? 419 TYR A O 1 ATOM 3243 C CB . TYR A 1 419 ? 29.321 66.199 -8.373 1.00 8.75 ? 419 TYR A CB 1 ATOM 3244 C CG . TYR A 1 419 ? 28.652 65.021 -7.718 1.00 10.10 ? 419 TYR A CG 1 ATOM 3245 C CD1 . TYR A 1 419 ? 27.465 64.510 -8.239 1.00 8.21 ? 419 TYR A CD1 1 ATOM 3246 C CD2 . TYR A 1 419 ? 29.243 64.362 -6.627 1.00 8.13 ? 419 TYR A CD2 1 ATOM 3247 C CE1 . TYR A 1 419 ? 26.889 63.370 -7.714 1.00 10.55 ? 419 TYR A CE1 1 ATOM 3248 C CE2 . TYR A 1 419 ? 28.678 63.224 -6.088 1.00 10.54 ? 419 TYR A CE2 1 ATOM 3249 C CZ . TYR A 1 419 ? 27.504 62.725 -6.643 1.00 11.21 ? 419 TYR A CZ 1 ATOM 3250 O OH . TYR A 1 419 ? 26.967 61.552 -6.187 1.00 11.21 ? 419 TYR A OH 1 ATOM 3251 N N . THR A 1 420 ? 30.334 69.393 -7.911 1.00 7.11 ? 420 THR A N 1 ATOM 3252 C CA . THR A 1 420 ? 30.718 70.638 -8.614 1.00 6.98 ? 420 THR A CA 1 ATOM 3253 C C . THR A 1 420 ? 31.288 71.776 -7.754 1.00 8.13 ? 420 THR A C 1 ATOM 3254 O O . THR A 1 420 ? 32.110 72.557 -8.247 1.00 9.20 ? 420 THR A O 1 ATOM 3255 C CB . THR A 1 420 ? 29.490 71.190 -9.438 1.00 8.60 ? 420 THR A CB 1 ATOM 3256 O OG1 . THR A 1 420 ? 28.971 70.143 -10.276 1.00 7.90 ? 420 THR A OG1 1 ATOM 3257 C CG2 . THR A 1 420 ? 29.895 72.354 -10.346 1.00 7.80 ? 420 THR A CG2 1 ATOM 3258 N N . SER A 1 421 ? 30.899 71.849 -6.476 1.00 8.73 ? 421 SER A N 1 ATOM 3259 C CA . SER A 1 421 ? 31.335 72.915 -5.573 1.00 8.59 ? 421 SER A CA 1 ATOM 3260 C C . SER A 1 421 ? 32.811 73.245 -5.646 1.00 8.74 ? 421 SER A C 1 ATOM 3261 O O . SER A 1 421 ? 33.651 72.340 -5.644 1.00 8.30 ? 421 SER A O 1 ATOM 3262 C CB . SER A 1 421 ? 30.944 72.587 -4.121 1.00 8.49 ? 421 SER A CB 1 ATOM 3263 O OG . SER A 1 421 ? 29.545 72.399 -4.021 1.00 8.02 ? 421 SER A OG 1 ATOM 3264 N N . ARG A 1 422 ? 33.119 74.547 -5.695 1.00 7.98 ? 422 ARG A N 1 ATOM 3265 C CA . ARG A 1 422 ? 34.509 75.029 -5.767 1.00 7.47 ? 422 ARG A CA 1 ATOM 3266 C C . ARG A 1 422 ? 35.217 74.346 -6.943 1.00 7.37 ? 422 ARG A C 1 ATOM 3267 O O . ARG A 1 422 ? 36.263 73.678 -6.790 1.00 7.95 ? 422 ARG A O 1 ATOM 3268 C CB . ARG A 1 422 ? 35.229 74.744 -4.444 1.00 6.69 ? 422 ARG A CB 1 ATOM 3269 C CG . ARG A 1 422 ? 35.048 75.866 -3.359 1.00 8.91 ? 422 ARG A CG 1 ATOM 3270 C CD . ARG A 1 422 ? 33.584 76.105 -2.907 1.00 8.33 ? 422 ARG A CD 1 ATOM 3271 N NE . ARG A 1 422 ? 33.584 77.067 -1.787 1.00 11.29 ? 422 ARG A NE 1 ATOM 3272 C CZ . ARG A 1 422 ? 33.540 76.726 -0.496 1.00 12.11 ? 422 ARG A CZ 1 ATOM 3273 N NH1 . ARG A 1 422 ? 33.444 75.457 -0.144 1.00 11.39 ? 422 ARG A NH1 1 ATOM 3274 N NH2 . ARG A 1 422 ? 33.724 77.642 0.455 1.00 13.23 ? 422 ARG A NH2 1 ATOM 3275 N N . PRO A 1 423 ? 34.682 74.548 -8.157 1.00 7.67 ? 423 PRO A N 1 ATOM 3276 C CA . PRO A 1 423 ? 35.284 73.925 -9.339 1.00 7.91 ? 423 PRO A CA 1 ATOM 3277 C C . PRO A 1 423 ? 36.703 74.379 -9.677 1.00 8.18 ? 423 PRO A C 1 ATOM 3278 O O . PRO A 1 423 ? 37.451 73.656 -10.370 1.00 7.96 ? 423 PRO A O 1 ATOM 3279 C CB . PRO A 1 423 ? 34.248 74.220 -10.451 1.00 9.29 ? 423 PRO A CB 1 ATOM 3280 C CG . PRO A 1 423 ? 33.752 75.581 -10.091 1.00 8.61 ? 423 PRO A CG 1 ATOM 3281 C CD . PRO A 1 423 ? 33.610 75.494 -8.534 1.00 7.34 ? 423 PRO A CD 1 ATOM 3282 N N . TYR A 1 424 ? 37.093 75.569 -9.237 1.00 7.34 ? 424 TYR A N 1 ATOM 3283 C CA . TYR A 1 424 ? 38.460 76.030 -9.516 1.00 8.22 ? 424 TYR A CA 1 ATOM 3284 C C . TYR A 1 424 ? 39.474 75.040 -8.947 1.00 7.78 ? 424 TYR A C 1 ATOM 3285 O O . TYR A 1 424 ? 40.424 74.626 -9.635 1.00 8.38 ? 424 TYR A O 1 ATOM 3286 C CB . TYR A 1 424 ? 38.708 77.385 -8.849 1.00 9.09 ? 424 TYR A CB 1 ATOM 3287 C CG . TYR A 1 424 ? 40.084 77.923 -9.128 1.00 10.66 ? 424 TYR A CG 1 ATOM 3288 C CD1 . TYR A 1 424 ? 40.329 78.686 -10.277 1.00 9.23 ? 424 TYR A CD1 1 ATOM 3289 C CD2 . TYR A 1 424 ? 41.138 77.699 -8.235 1.00 10.24 ? 424 TYR A CD2 1 ATOM 3290 C CE1 . TYR A 1 424 ? 41.561 79.213 -10.525 1.00 12.23 ? 424 TYR A CE1 1 ATOM 3291 C CE2 . TYR A 1 424 ? 42.403 78.226 -8.482 1.00 11.48 ? 424 TYR A CE2 1 ATOM 3292 C CZ . TYR A 1 424 ? 42.613 78.989 -9.628 1.00 12.86 ? 424 TYR A CZ 1 ATOM 3293 O OH . TYR A 1 424 ? 43.857 79.555 -9.888 1.00 12.73 ? 424 TYR A OH 1 ATOM 3294 N N . HIS A 1 425 ? 39.260 74.643 -7.685 1.00 7.94 ? 425 HIS A N 1 ATOM 3295 C CA . HIS A 1 425 ? 40.183 73.730 -6.997 1.00 7.63 ? 425 HIS A CA 1 ATOM 3296 C C . HIS A 1 425 ? 40.029 72.285 -7.480 1.00 8.12 ? 425 HIS A C 1 ATOM 3297 O O . HIS A 1 425 ? 40.950 71.482 -7.350 1.00 7.95 ? 425 HIS A O 1 ATOM 3298 C CB . HIS A 1 425 ? 39.978 73.845 -5.481 1.00 8.68 ? 425 HIS A CB 1 ATOM 3299 C CG . HIS A 1 425 ? 40.013 75.265 -4.999 1.00 10.37 ? 425 HIS A CG 1 ATOM 3300 N ND1 . HIS A 1 425 ? 38.892 76.068 -4.994 1.00 12.40 ? 425 HIS A ND1 1 ATOM 3301 C CD2 . HIS A 1 425 ? 41.059 76.078 -4.707 1.00 8.82 ? 425 HIS A CD2 1 ATOM 3302 C CE1 . HIS A 1 425 ? 39.247 77.315 -4.729 1.00 11.42 ? 425 HIS A CE1 1 ATOM 3303 N NE2 . HIS A 1 425 ? 40.555 77.347 -4.555 1.00 12.46 ? 425 HIS A NE2 1 ATOM 3304 N N . LYS A 1 426 ? 38.858 71.953 -8.010 1.00 7.55 ? 426 LYS A N 1 ATOM 3305 C CA . LYS A 1 426 ? 38.642 70.621 -8.550 1.00 7.94 ? 426 LYS A CA 1 ATOM 3306 C C . LYS A 1 426 ? 39.508 70.536 -9.829 1.00 8.85 ? 426 LYS A C 1 ATOM 3307 O O . LYS A 1 426 ? 40.092 69.500 -10.131 1.00 9.33 ? 426 LYS A O 1 ATOM 3308 C CB . LYS A 1 426 ? 37.149 70.410 -8.907 1.00 9.62 ? 426 LYS A CB 1 ATOM 3309 C CG . LYS A 1 426 ? 36.226 70.109 -7.716 1.00 8.20 ? 426 LYS A CG 1 ATOM 3310 C CD . LYS A 1 426 ? 34.747 69.976 -8.161 1.00 10.10 ? 426 LYS A CD 1 ATOM 3311 C CE . LYS A 1 426 ? 33.902 69.156 -7.142 1.00 9.43 ? 426 LYS A CE 1 ATOM 3312 N NZ . LYS A 1 426 ? 34.006 69.675 -5.726 1.00 9.57 ? 426 LYS A NZ 1 ATOM 3313 N N . ARG A 1 427 ? 39.598 71.636 -10.576 1.00 7.77 ? 427 ARG A N 1 ATOM 3314 C CA . ARG A 1 427 ? 40.421 71.649 -11.806 1.00 7.20 ? 427 ARG A CA 1 ATOM 3315 C C . ARG A 1 427 ? 41.890 71.660 -11.363 1.00 7.05 ? 427 ARG A C 1 ATOM 3316 O O . ARG A 1 427 ? 42.721 70.939 -11.897 1.00 7.30 ? 427 ARG A O 1 ATOM 3317 C CB . ARG A 1 427 ? 40.052 72.892 -12.659 1.00 8.04 ? 427 ARG A CB 1 ATOM 3318 C CG . ARG A 1 427 ? 40.995 73.213 -13.855 1.00 9.40 ? 427 ARG A CG 1 ATOM 3319 C CD . ARG A 1 427 ? 41.299 71.995 -14.785 1.00 10.32 ? 427 ARG A CD 1 ATOM 3320 N NE . ARG A 1 427 ? 42.280 72.406 -15.788 1.00 11.53 ? 427 ARG A NE 1 ATOM 3321 C CZ . ARG A 1 427 ? 43.051 71.583 -16.487 1.00 12.01 ? 427 ARG A CZ 1 ATOM 3322 N NH1 . ARG A 1 427 ? 42.960 70.273 -16.310 1.00 11.20 ? 427 ARG A NH1 1 ATOM 3323 N NH2 . ARG A 1 427 ? 43.957 72.088 -17.325 1.00 11.09 ? 427 ARG A NH2 1 ATOM 3324 N N . MET A 1 428 ? 42.193 72.457 -10.346 1.00 7.36 ? 428 MET A N 1 ATOM 3325 C CA . MET A 1 428 ? 43.551 72.522 -9.842 1.00 8.35 ? 428 MET A CA 1 ATOM 3326 C C . MET A 1 428 ? 44.066 71.135 -9.410 1.00 7.92 ? 428 MET A C 1 ATOM 3327 O O . MET A 1 428 ? 45.252 70.812 -9.586 1.00 6.01 ? 428 MET A O 1 ATOM 3328 C CB . MET A 1 428 ? 43.610 73.504 -8.667 1.00 10.10 ? 428 MET A CB 1 ATOM 3329 C CG . MET A 1 428 ? 45.047 73.790 -8.198 1.00 12.20 ? 428 MET A CG 1 ATOM 3330 S SD . MET A 1 428 ? 45.037 75.152 -6.997 1.00 11.94 ? 428 MET A SD 1 ATOM 3331 C CE . MET A 1 428 ? 46.801 75.680 -7.042 1.00 10.68 ? 428 MET A CE 1 ATOM 3332 N N . ASP A 1 429 ? 43.164 70.318 -8.852 1.00 8.20 ? 429 ASP A N 1 ATOM 3333 C CA . ASP A 1 429 ? 43.501 68.959 -8.431 1.00 8.07 ? 429 ASP A CA 1 ATOM 3334 C C . ASP A 1 429 ? 44.093 68.123 -9.563 1.00 7.61 ? 429 ASP A C 1 ATOM 3335 O O . ASP A 1 429 ? 45.103 67.450 -9.381 1.00 7.29 ? 429 ASP A O 1 ATOM 3336 C CB . ASP A 1 429 ? 42.275 68.235 -7.884 1.00 7.29 ? 429 ASP A CB 1 ATOM 3337 C CG . ASP A 1 429 ? 42.564 66.757 -7.599 1.00 10.73 ? 429 ASP A CG 1 ATOM 3338 O OD1 . ASP A 1 429 ? 42.295 65.919 -8.509 1.00 8.92 ? 429 ASP A OD1 1 ATOM 3339 O OD2 . ASP A 1 429 ? 43.076 66.455 -6.482 1.00 7.43 ? 429 ASP A OD2 1 ATOM 3340 N N . ARG A 1 430 ? 43.479 68.201 -10.745 1.00 7.34 ? 430 ARG A N 1 ATOM 3341 C CA . ARG A 1 430 ? 43.939 67.444 -11.893 1.00 7.61 ? 430 ARG A CA 1 ATOM 3342 C C . ARG A 1 430 ? 45.243 67.971 -12.444 1.00 8.50 ? 430 ARG A C 1 ATOM 3343 O O . ARG A 1 430 ? 46.079 67.214 -12.976 1.00 8.76 ? 430 ARG A O 1 ATOM 3344 C CB . ARG A 1 430 ? 42.857 67.477 -12.988 1.00 8.38 ? 430 ARG A CB 1 ATOM 3345 C CG . ARG A 1 430 ? 41.554 66.813 -12.570 1.00 10.38 ? 430 ARG A CG 1 ATOM 3346 C CD . ARG A 1 430 ? 41.762 65.344 -12.158 1.00 8.87 ? 430 ARG A CD 1 ATOM 3347 N NE . ARG A 1 430 ? 40.515 64.610 -12.175 1.00 7.86 ? 430 ARG A NE 1 ATOM 3348 C CZ . ARG A 1 430 ? 39.826 64.301 -11.083 1.00 9.42 ? 430 ARG A CZ 1 ATOM 3349 N NH1 . ARG A 1 430 ? 40.267 64.656 -9.871 1.00 7.32 ? 430 ARG A NH1 1 ATOM 3350 N NH2 . ARG A 1 430 ? 38.662 63.654 -11.201 1.00 9.32 ? 430 ARG A NH2 1 ATOM 3351 N N . VAL A 1 431 ? 45.425 69.283 -12.342 1.00 7.49 ? 431 VAL A N 1 ATOM 3352 C CA . VAL A 1 431 ? 46.660 69.866 -12.821 1.00 7.27 ? 431 VAL A CA 1 ATOM 3353 C C . VAL A 1 431 ? 47.814 69.382 -11.921 1.00 7.12 ? 431 VAL A C 1 ATOM 3354 O O . VAL A 1 431 ? 48.872 68.935 -12.417 1.00 8.50 ? 431 VAL A O 1 ATOM 3355 C CB . VAL A 1 431 ? 46.573 71.407 -12.813 1.00 8.08 ? 431 VAL A CB 1 ATOM 3356 C CG1 . VAL A 1 431 ? 47.973 72.034 -13.096 1.00 7.80 ? 431 VAL A CG1 1 ATOM 3357 C CG2 . VAL A 1 431 ? 45.538 71.879 -13.888 1.00 5.97 ? 431 VAL A CG2 1 ATOM 3358 N N . LEU A 1 432 ? 47.625 69.476 -10.606 1.00 6.74 ? 432 LEU A N 1 ATOM 3359 C CA . LEU A 1 432 ? 48.674 69.047 -9.688 1.00 7.34 ? 432 LEU A CA 1 ATOM 3360 C C . LEU A 1 432 ? 48.906 67.535 -9.802 1.00 7.08 ? 432 LEU A C 1 ATOM 3361 O O . LEU A 1 432 ? 50.034 67.074 -9.710 1.00 7.45 ? 432 LEU A O 1 ATOM 3362 C CB . LEU A 1 432 ? 48.339 69.414 -8.246 1.00 6.73 ? 432 LEU A CB 1 ATOM 3363 C CG . LEU A 1 432 ? 49.374 69.113 -7.152 1.00 6.94 ? 432 LEU A CG 1 ATOM 3364 C CD1 . LEU A 1 432 ? 50.782 69.610 -7.514 1.00 4.42 ? 432 LEU A CD1 1 ATOM 3365 C CD2 . LEU A 1 432 ? 48.890 69.807 -5.849 1.00 5.50 ? 432 LEU A CD2 1 ATOM 3366 N N . MET A 1 433 ? 47.828 66.779 -9.977 1.00 7.58 ? 433 MET A N 1 ATOM 3367 C CA . MET A 1 433 ? 47.942 65.329 -10.162 1.00 7.19 ? 433 MET A CA 1 ATOM 3368 C C . MET A 1 433 ? 49.012 65.028 -11.226 1.00 5.99 ? 433 MET A C 1 ATOM 3369 O O . MET A 1 433 ? 49.937 64.215 -11.015 1.00 5.68 ? 433 MET A O 1 ATOM 3370 C CB . MET A 1 433 ? 46.603 64.732 -10.641 1.00 6.19 ? 433 MET A CB 1 ATOM 3371 C CG . MET A 1 433 ? 46.738 63.248 -10.999 1.00 8.40 ? 433 MET A CG 1 ATOM 3372 S SD . MET A 1 433 ? 45.211 62.575 -11.683 1.00 9.18 ? 433 MET A SD 1 ATOM 3373 C CE . MET A 1 433 ? 45.254 63.172 -13.436 1.00 8.14 ? 433 MET A CE 1 ATOM 3374 N N . HIS A 1 434 ? 48.913 65.734 -12.353 1.00 6.12 ? 434 HIS A N 1 ATOM 3375 C CA . HIS A 1 434 ? 49.843 65.526 -13.460 1.00 6.52 ? 434 HIS A CA 1 ATOM 3376 C C . HIS A 1 434 ? 51.261 66.043 -13.176 1.00 7.84 ? 434 HIS A C 1 ATOM 3377 O O . HIS A 1 434 ? 52.249 65.386 -13.527 1.00 6.31 ? 434 HIS A O 1 ATOM 3378 C CB . HIS A 1 434 ? 49.293 66.172 -14.748 1.00 6.34 ? 434 HIS A CB 1 ATOM 3379 C CG . HIS A 1 434 ? 50.299 66.215 -15.848 1.00 7.25 ? 434 HIS A CG 1 ATOM 3380 N ND1 . HIS A 1 434 ? 50.767 65.068 -16.466 1.00 8.39 ? 434 HIS A ND1 1 ATOM 3381 C CD2 . HIS A 1 434 ? 51.043 67.239 -16.339 1.00 6.75 ? 434 HIS A CD2 1 ATOM 3382 C CE1 . HIS A 1 434 ? 51.765 65.390 -17.275 1.00 6.38 ? 434 HIS A CE1 1 ATOM 3383 N NE2 . HIS A 1 434 ? 51.951 66.698 -17.216 1.00 7.51 ? 434 HIS A NE2 1 ATOM 3384 N N . TYR A 1 435 ? 51.360 67.216 -12.534 1.00 7.69 ? 435 TYR A N 1 ATOM 3385 C CA . TYR A 1 435 ? 52.669 67.792 -12.221 1.00 8.86 ? 435 TYR A CA 1 ATOM 3386 C C . TYR A 1 435 ? 53.402 66.866 -11.267 1.00 7.91 ? 435 TYR A C 1 ATOM 3387 O O . TYR A 1 435 ? 54.607 66.665 -11.403 1.00 7.96 ? 435 TYR A O 1 ATOM 3388 C CB . TYR A 1 435 ? 52.543 69.167 -11.555 1.00 10.36 ? 435 TYR A CB 1 ATOM 3389 C CG . TYR A 1 435 ? 52.381 70.320 -12.510 1.00 14.51 ? 435 TYR A CG 1 ATOM 3390 C CD1 . TYR A 1 435 ? 51.388 70.317 -13.497 1.00 16.27 ? 435 TYR A CD1 1 ATOM 3391 C CD2 . TYR A 1 435 ? 53.198 71.459 -12.393 1.00 19.79 ? 435 TYR A CD2 1 ATOM 3392 C CE1 . TYR A 1 435 ? 51.196 71.398 -14.344 1.00 16.79 ? 435 TYR A CE1 1 ATOM 3393 C CE2 . TYR A 1 435 ? 53.017 72.561 -13.244 1.00 20.56 ? 435 TYR A CE2 1 ATOM 3394 C CZ . TYR A 1 435 ? 52.013 72.514 -14.214 1.00 21.83 ? 435 TYR A CZ 1 ATOM 3395 O OH . TYR A 1 435 ? 51.864 73.592 -15.057 1.00 24.35 ? 435 TYR A OH 1 ATOM 3396 N N . VAL A 1 436 ? 52.672 66.305 -10.303 1.00 6.49 ? 436 VAL A N 1 ATOM 3397 C CA . VAL A 1 436 ? 53.315 65.395 -9.355 1.00 7.40 ? 436 VAL A CA 1 ATOM 3398 C C . VAL A 1 436 ? 53.856 64.194 -10.120 1.00 7.88 ? 436 VAL A C 1 ATOM 3399 O O . VAL A 1 436 ? 55.026 63.806 -9.978 1.00 8.82 ? 436 VAL A O 1 ATOM 3400 C CB . VAL A 1 436 ? 52.327 64.940 -8.223 1.00 6.00 ? 436 VAL A CB 1 ATOM 3401 C CG1 . VAL A 1 436 ? 52.881 63.698 -7.508 1.00 7.43 ? 436 VAL A CG1 1 ATOM 3402 C CG2 . VAL A 1 436 ? 52.148 66.090 -7.190 1.00 7.05 ? 436 VAL A CG2 1 ATOM 3403 N N . ARG A 1 437 ? 53.017 63.599 -10.961 1.00 7.41 ? 437 ARG A N 1 ATOM 3404 C CA . ARG A 1 437 ? 53.499 62.447 -11.713 1.00 7.49 ? 437 ARG A CA 1 ATOM 3405 C C . ARG A 1 437 ? 54.705 62.819 -12.596 1.00 7.22 ? 437 ARG A C 1 ATOM 3406 O O . ARG A 1 437 ? 55.704 62.069 -12.652 1.00 8.22 ? 437 ARG A O 1 ATOM 3407 C CB . ARG A 1 437 ? 52.363 61.856 -12.580 1.00 6.67 ? 437 ARG A CB 1 ATOM 3408 C CG . ARG A 1 437 ? 52.870 60.988 -13.721 1.00 8.13 ? 437 ARG A CG 1 ATOM 3409 C CD . ARG A 1 437 ? 51.762 60.377 -14.602 1.00 6.10 ? 437 ARG A CD 1 ATOM 3410 N NE . ARG A 1 437 ? 52.306 59.734 -15.794 1.00 5.55 ? 437 ARG A NE 1 ATOM 3411 C CZ . ARG A 1 437 ? 51.585 58.950 -16.593 1.00 6.76 ? 437 ARG A CZ 1 ATOM 3412 N NH1 . ARG A 1 437 ? 50.301 58.730 -16.307 1.00 5.07 ? 437 ARG A NH1 1 ATOM 3413 N NH2 . ARG A 1 437 ? 52.131 58.392 -17.677 1.00 7.67 ? 437 ARG A NH2 1 ATOM 3414 N N . ALA A 1 438 ? 54.639 63.965 -13.281 1.00 6.51 ? 438 ALA A N 1 ATOM 3415 C CA . ALA A 1 438 ? 55.734 64.349 -14.172 1.00 6.80 ? 438 ALA A CA 1 ATOM 3416 C C . ALA A 1 438 ? 57.045 64.648 -13.406 1.00 6.87 ? 438 ALA A C 1 ATOM 3417 O O . ALA A 1 438 ? 58.132 64.308 -13.873 1.00 6.53 ? 438 ALA A O 1 ATOM 3418 C CB . ALA A 1 438 ? 55.316 65.574 -15.078 1.00 6.34 ? 438 ALA A CB 1 ATOM 3419 N N . ALA A 1 439 ? 56.928 65.271 -12.235 1.00 5.92 ? 439 ALA A N 1 ATOM 3420 C CA . ALA A 1 439 ? 58.082 65.577 -11.418 1.00 5.77 ? 439 ALA A CA 1 ATOM 3421 C C . ALA A 1 439 ? 58.723 64.285 -10.887 1.00 6.83 ? 439 ALA A C 1 ATOM 3422 O O . ALA A 1 439 ? 59.943 64.121 -10.944 1.00 6.50 ? 439 ALA A O 1 ATOM 3423 C CB . ALA A 1 439 ? 57.674 66.510 -10.244 1.00 4.63 ? 439 ALA A CB 1 ATOM 3424 N N . GLU A 1 440 ? 57.911 63.381 -10.361 1.00 5.73 ? 440 GLU A N 1 ATOM 3425 C CA . GLU A 1 440 ? 58.457 62.133 -9.855 1.00 6.93 ? 440 GLU A CA 1 ATOM 3426 C C . GLU A 1 440 ? 59.112 61.312 -10.973 1.00 6.71 ? 440 GLU A C 1 ATOM 3427 O O . GLU A 1 440 ? 60.153 60.682 -10.784 1.00 8.71 ? 440 GLU A O 1 ATOM 3428 C CB . GLU A 1 440 ? 57.343 61.318 -9.168 1.00 7.38 ? 440 GLU A CB 1 ATOM 3429 C CG . GLU A 1 440 ? 56.885 61.936 -7.866 1.00 7.06 ? 440 GLU A CG 1 ATOM 3430 C CD . GLU A 1 440 ? 56.153 60.928 -6.978 1.00 10.56 ? 440 GLU A CD 1 ATOM 3431 O OE1 . GLU A 1 440 ? 55.030 60.531 -7.324 1.00 9.64 ? 440 GLU A OE1 1 ATOM 3432 O OE2 . GLU A 1 440 ? 56.727 60.504 -5.948 1.00 13.11 ? 440 GLU A OE2 1 ATOM 3433 N N . MET A 1 441 ? 58.516 61.334 -12.153 1.00 8.56 ? 441 MET A N 1 ATOM 3434 C CA . MET A 1 441 ? 59.061 60.575 -13.278 1.00 7.01 ? 441 MET A CA 1 ATOM 3435 C C . MET A 1 441 ? 60.369 61.156 -13.832 1.00 7.19 ? 441 MET A C 1 ATOM 3436 O O . MET A 1 441 ? 61.375 60.439 -13.974 1.00 6.92 ? 441 MET A O 1 ATOM 3437 C CB . MET A 1 441 ? 58.024 60.469 -14.404 1.00 6.65 ? 441 MET A CB 1 ATOM 3438 C CG . MET A 1 441 ? 58.524 59.678 -15.616 1.00 6.95 ? 441 MET A CG 1 ATOM 3439 S SD . MET A 1 441 ? 57.241 59.393 -16.875 1.00 8.28 ? 441 MET A SD 1 ATOM 3440 C CE . MET A 1 441 ? 56.167 58.197 -16.045 1.00 5.96 ? 441 MET A CE 1 ATOM 3441 N N . LEU A 1 442 ? 60.369 62.454 -14.117 1.00 6.97 ? 442 LEU A N 1 ATOM 3442 C CA . LEU A 1 442 ? 61.554 63.123 -14.663 1.00 7.71 ? 442 LEU A CA 1 ATOM 3443 C C . LEU A 1 442 ? 62.768 63.020 -13.751 1.00 9.73 ? 442 LEU A C 1 ATOM 3444 O O . LEU A 1 442 ? 63.885 62.811 -14.238 1.00 9.64 ? 442 LEU A O 1 ATOM 3445 C CB . LEU A 1 442 ? 61.246 64.606 -14.967 1.00 8.31 ? 442 LEU A CB 1 ATOM 3446 C CG . LEU A 1 442 ? 60.577 64.839 -16.342 1.00 9.56 ? 442 LEU A CG 1 ATOM 3447 C CD1 . LEU A 1 442 ? 60.024 66.269 -16.419 1.00 10.48 ? 442 LEU A CD1 1 ATOM 3448 C CD2 . LEU A 1 442 ? 61.596 64.605 -17.478 1.00 8.59 ? 442 LEU A CD2 1 ATOM 3449 N N . SER A 1 443 ? 62.561 63.121 -12.436 1.00 8.29 ? 443 SER A N 1 ATOM 3450 C CA . SER A 1 443 ? 63.698 63.052 -11.515 1.00 9.29 ? 443 SER A CA 1 ATOM 3451 C C . SER A 1 443 ? 64.080 61.609 -11.122 1.00 9.74 ? 443 SER A C 1 ATOM 3452 O O . SER A 1 443 ? 65.168 61.367 -10.548 1.00 9.90 ? 443 SER A O 1 ATOM 3453 C CB . SER A 1 443 ? 63.406 63.883 -10.267 1.00 9.41 ? 443 SER A CB 1 ATOM 3454 O OG . SER A 1 443 ? 62.319 63.342 -9.527 1.00 9.50 ? 443 SER A OG 1 ATOM 3455 N N . ALA A 1 444 ? 63.204 60.655 -11.449 1.00 9.16 ? 444 ALA A N 1 ATOM 3456 C CA . ALA A 1 444 ? 63.457 59.247 -11.118 1.00 9.24 ? 444 ALA A CA 1 ATOM 3457 C C . ALA A 1 444 ? 64.609 58.699 -11.933 1.00 10.59 ? 444 ALA A C 1 ATOM 3458 O O . ALA A 1 444 ? 65.296 57.768 -11.494 1.00 11.12 ? 444 ALA A O 1 ATOM 3459 C CB . ALA A 1 444 ? 62.240 58.406 -11.395 1.00 8.56 ? 444 ALA A CB 1 ATOM 3460 N N . TRP A 1 445 ? 64.831 59.263 -13.116 1.00 11.48 ? 445 TRP A N 1 ATOM 3461 C CA . TRP A 1 445 ? 65.881 58.755 -13.980 1.00 11.90 ? 445 TRP A CA 1 ATOM 3462 C C . TRP A 1 445 ? 67.270 58.790 -13.362 1.00 13.37 ? 445 TRP A C 1 ATOM 3463 O O . TRP A 1 445 ? 68.102 57.949 -13.675 1.00 12.41 ? 445 TRP A O 1 ATOM 3464 C CB . TRP A 1 445 ? 65.885 59.507 -15.315 1.00 11.55 ? 445 TRP A CB 1 ATOM 3465 C CG . TRP A 1 445 ? 64.622 59.303 -16.068 1.00 9.96 ? 445 TRP A CG 1 ATOM 3466 C CD1 . TRP A 1 445 ? 63.623 60.212 -16.242 1.00 10.60 ? 445 TRP A CD1 1 ATOM 3467 C CD2 . TRP A 1 445 ? 64.194 58.095 -16.729 1.00 9.51 ? 445 TRP A CD2 1 ATOM 3468 N NE1 . TRP A 1 445 ? 62.597 59.652 -16.964 1.00 9.36 ? 445 TRP A NE1 1 ATOM 3469 C CE2 . TRP A 1 445 ? 62.921 58.352 -17.276 1.00 10.14 ? 445 TRP A CE2 1 ATOM 3470 C CE3 . TRP A 1 445 ? 64.774 56.817 -16.914 1.00 10.16 ? 445 TRP A CE3 1 ATOM 3471 C CZ2 . TRP A 1 445 ? 62.202 57.386 -17.998 1.00 10.22 ? 445 TRP A CZ2 1 ATOM 3472 C CZ3 . TRP A 1 445 ? 64.061 55.855 -17.633 1.00 10.31 ? 445 TRP A CZ3 1 ATOM 3473 C CH2 . TRP A 1 445 ? 62.781 56.148 -18.167 1.00 9.96 ? 445 TRP A CH2 1 ATOM 3474 N N . HIS A 1 446 ? 67.511 59.746 -12.479 1.00 13.94 ? 446 HIS A N 1 ATOM 3475 C CA . HIS A 1 446 ? 68.815 59.878 -11.853 1.00 15.33 ? 446 HIS A CA 1 ATOM 3476 C C . HIS A 1 446 ? 68.668 59.766 -10.359 1.00 16.84 ? 446 HIS A C 1 ATOM 3477 O O . HIS A 1 446 ? 67.577 59.935 -9.817 1.00 16.52 ? 446 HIS A O 1 ATOM 3478 C CB . HIS A 1 446 ? 69.403 61.272 -12.088 1.00 16.72 ? 446 HIS A CB 1 ATOM 3479 C CG . HIS A 1 446 ? 69.870 61.525 -13.485 1.00 18.95 ? 446 HIS A CG 1 ATOM 3480 N ND1 . HIS A 1 446 ? 69.146 62.272 -14.383 1.00 18.80 ? 446 HIS A ND1 1 ATOM 3481 C CD2 . HIS A 1 446 ? 71.015 61.173 -14.122 1.00 20.23 ? 446 HIS A CD2 1 ATOM 3482 C CE1 . HIS A 1 446 ? 69.821 62.375 -15.517 1.00 20.62 ? 446 HIS A CE1 1 ATOM 3483 N NE2 . HIS A 1 446 ? 70.958 61.717 -15.383 1.00 20.78 ? 446 HIS A NE2 1 ATOM 3484 N N . SER A 1 447 ? 69.808 59.550 -9.712 1.00 16.67 ? 447 SER A N 1 ATOM 3485 C CA . SER A 1 447 ? 69.921 59.527 -8.262 1.00 16.20 ? 447 SER A CA 1 ATOM 3486 C C . SER A 1 447 ? 70.422 60.963 -7.976 1.00 16.53 ? 447 SER A C 1 ATOM 3487 O O . SER A 1 447 ? 71.301 61.464 -8.695 1.00 16.48 ? 447 SER A O 1 ATOM 3488 C CB . SER A 1 447 ? 70.962 58.488 -7.849 1.00 17.19 ? 447 SER A CB 1 ATOM 3489 O OG . SER A 1 447 ? 70.784 58.135 -6.506 1.00 18.70 ? 447 SER A OG 1 ATOM 3490 N N . TRP A 1 448 ? 69.877 61.634 -6.961 1.00 15.59 ? 448 TRP A N 1 ATOM 3491 C CA . TRP A 1 448 ? 70.273 63.007 -6.711 1.00 16.59 ? 448 TRP A CA 1 ATOM 3492 C C . TRP A 1 448 ? 70.953 63.278 -5.391 1.00 17.77 ? 448 TRP A C 1 ATOM 3493 O O . TRP A 1 448 ? 70.591 62.715 -4.364 1.00 17.13 ? 448 TRP A O 1 ATOM 3494 C CB . TRP A 1 448 ? 69.063 63.961 -6.800 1.00 14.73 ? 448 TRP A CB 1 ATOM 3495 C CG . TRP A 1 448 ? 68.384 63.974 -8.136 1.00 13.09 ? 448 TRP A CG 1 ATOM 3496 C CD1 . TRP A 1 448 ? 67.563 63.029 -8.643 1.00 12.84 ? 448 TRP A CD1 1 ATOM 3497 C CD2 . TRP A 1 448 ? 68.524 64.977 -9.146 1.00 13.59 ? 448 TRP A CD2 1 ATOM 3498 N NE1 . TRP A 1 448 ? 67.174 63.372 -9.915 1.00 12.92 ? 448 TRP A NE1 1 ATOM 3499 C CE2 . TRP A 1 448 ? 67.745 64.571 -10.245 1.00 12.89 ? 448 TRP A CE2 1 ATOM 3500 C CE3 . TRP A 1 448 ? 69.239 66.185 -9.225 1.00 13.85 ? 448 TRP A CE3 1 ATOM 3501 C CZ2 . TRP A 1 448 ? 67.648 65.326 -11.415 1.00 13.16 ? 448 TRP A CZ2 1 ATOM 3502 C CZ3 . TRP A 1 448 ? 69.146 66.936 -10.387 1.00 13.35 ? 448 TRP A CZ3 1 ATOM 3503 C CH2 . TRP A 1 448 ? 68.351 66.501 -11.467 1.00 13.66 ? 448 TRP A CH2 1 ATOM 3504 N N . ASP A 1 449 ? 71.949 64.158 -5.442 1.00 19.55 ? 449 ASP A N 1 ATOM 3505 C CA . ASP A 1 449 ? 72.651 64.559 -4.235 1.00 20.85 ? 449 ASP A CA 1 ATOM 3506 C C . ASP A 1 449 ? 71.618 65.223 -3.313 1.00 20.34 ? 449 ASP A C 1 ATOM 3507 O O . ASP A 1 449 ? 70.765 65.975 -3.774 1.00 19.19 ? 449 ASP A O 1 ATOM 3508 C CB . ASP A 1 449 ? 73.742 65.574 -4.575 1.00 23.90 ? 449 ASP A CB 1 ATOM 3509 C CG . ASP A 1 449 ? 74.581 65.932 -3.373 1.00 27.44 ? 449 ASP A CG 1 ATOM 3510 O OD1 . ASP A 1 449 ? 74.357 66.993 -2.744 1.00 27.96 ? 449 ASP A OD1 1 ATOM 3511 O OD2 . ASP A 1 449 ? 75.463 65.108 -3.038 1.00 31.86 ? 449 ASP A OD2 1 ATOM 3512 N N . GLY A 1 450 ? 71.718 64.967 -2.012 1.00 19.85 ? 450 GLY A N 1 ATOM 3513 C CA . GLY A 1 450 ? 70.781 65.554 -1.070 1.00 20.54 ? 450 GLY A CA 1 ATOM 3514 C C . GLY A 1 450 ? 70.697 67.056 -1.165 1.00 20.73 ? 450 GLY A C 1 ATOM 3515 O O . GLY A 1 450 ? 69.672 67.651 -0.833 1.00 21.49 ? 450 GLY A O 1 ATOM 3516 N N . MET A 1 451 ? 71.768 67.685 -1.618 1.00 20.46 ? 451 MET A N 1 ATOM 3517 C CA . MET A 1 451 ? 71.773 69.133 -1.736 1.00 21.71 ? 451 MET A CA 1 ATOM 3518 C C . MET A 1 451 ? 70.812 69.610 -2.820 1.00 19.89 ? 451 MET A C 1 ATOM 3519 O O . MET A 1 451 ? 70.499 70.796 -2.898 1.00 18.77 ? 451 MET A O 1 ATOM 3520 C CB . MET A 1 451 ? 73.186 69.643 -2.066 1.00 26.05 ? 451 MET A CB 1 ATOM 3521 C CG . MET A 1 451 ? 74.207 69.508 -0.933 1.00 32.08 ? 451 MET A CG 1 ATOM 3522 S SD . MET A 1 451 ? 73.794 70.544 0.551 1.00 41.73 ? 451 MET A SD 1 ATOM 3523 C CE . MET A 1 451 ? 73.073 69.243 1.736 1.00 37.70 ? 451 MET A CE 1 ATOM 3524 N N . ALA A 1 452 ? 70.382 68.700 -3.689 1.00 18.21 ? 452 ALA A N 1 ATOM 3525 C CA . ALA A 1 452 ? 69.460 69.085 -4.757 1.00 17.72 ? 452 ALA A CA 1 ATOM 3526 C C . ALA A 1 452 ? 68.054 69.320 -4.205 1.00 16.62 ? 452 ALA A C 1 ATOM 3527 O O . ALA A 1 452 ? 67.216 69.947 -4.858 1.00 16.49 ? 452 ALA A O 1 ATOM 3528 C CB . ALA A 1 452 ? 69.432 68.002 -5.859 1.00 16.87 ? 452 ALA A CB 1 ATOM 3529 N N . ARG A 1 453 ? 67.807 68.803 -3.005 1.00 15.49 ? 453 ARG A N 1 ATOM 3530 C CA . ARG A 1 453 ? 66.503 68.947 -2.345 1.00 14.89 ? 453 ARG A CA 1 ATOM 3531 C C . ARG A 1 453 ? 65.364 68.402 -3.208 1.00 13.87 ? 453 ARG A C 1 ATOM 3532 O O . ARG A 1 453 ? 64.263 68.947 -3.216 1.00 14.71 ? 453 ARG A O 1 ATOM 3533 C CB . ARG A 1 453 ? 66.257 70.421 -2.017 1.00 15.25 ? 453 ARG A CB 1 ATOM 3534 C CG . ARG A 1 453 ? 67.262 71.015 -1.021 1.00 16.66 ? 453 ARG A CG 1 ATOM 3535 C CD . ARG A 1 453 ? 67.036 72.518 -0.856 1.00 18.75 ? 453 ARG A CD 1 ATOM 3536 N NE . ARG A 1 453 ? 65.860 72.805 -0.030 1.00 21.45 ? 453 ARG A NE 1 ATOM 3537 C CZ . ARG A 1 453 ? 65.369 74.025 0.193 1.00 23.96 ? 453 ARG A CZ 1 ATOM 3538 N NH1 . ARG A 1 453 ? 65.955 75.108 -0.352 1.00 23.55 ? 453 ARG A NH1 1 ATOM 3539 N NH2 . ARG A 1 453 ? 64.287 74.165 0.950 1.00 22.84 ? 453 ARG A NH2 1 ATOM 3540 N N . ILE A 1 454 ? 65.640 67.325 -3.934 1.00 12.51 ? 454 ILE A N 1 ATOM 3541 C CA . ILE A 1 454 ? 64.647 66.722 -4.807 1.00 12.30 ? 454 ILE A CA 1 ATOM 3542 C C . ILE A 1 454 ? 63.625 65.951 -3.982 1.00 13.02 ? 454 ILE A C 1 ATOM 3543 O O . ILE A 1 454 ? 62.425 66.136 -4.158 1.00 12.70 ? 454 ILE A O 1 ATOM 3544 C CB . ILE A 1 454 ? 65.291 65.764 -5.799 1.00 12.22 ? 454 ILE A CB 1 ATOM 3545 C CG1 . ILE A 1 454 ? 66.294 66.535 -6.702 1.00 11.13 ? 454 ILE A CG1 1 ATOM 3546 C CG2 . ILE A 1 454 ? 64.189 65.046 -6.614 1.00 11.05 ? 454 ILE A CG2 1 ATOM 3547 C CD1 . ILE A 1 454 ? 65.675 67.635 -7.612 1.00 11.29 ? 454 ILE A CD1 1 ATOM 3548 N N . GLU A 1 455 ? 64.116 65.096 -3.088 1.00 11.58 ? 455 GLU A N 1 ATOM 3549 C CA . GLU A 1 455 ? 63.257 64.299 -2.229 1.00 12.42 ? 455 GLU A CA 1 ATOM 3550 C C . GLU A 1 455 ? 62.379 65.198 -1.384 1.00 12.26 ? 455 GLU A C 1 ATOM 3551 O O . GLU A 1 455 ? 61.188 64.895 -1.155 1.00 10.13 ? 455 GLU A O 1 ATOM 3552 C CB . GLU A 1 455 ? 64.076 63.395 -1.281 1.00 12.38 ? 455 GLU A CB 1 ATOM 3553 C CG . GLU A 1 455 ? 64.696 62.129 -1.928 1.00 13.82 ? 455 GLU A CG 1 ATOM 3554 C CD . GLU A 1 455 ? 66.010 62.386 -2.688 1.00 16.17 ? 455 GLU A CD 1 ATOM 3555 O OE1 . GLU A 1 455 ? 66.449 63.562 -2.768 1.00 16.76 ? 455 GLU A OE1 1 ATOM 3556 O OE2 . GLU A 1 455 ? 66.581 61.403 -3.223 1.00 13.21 ? 455 GLU A OE2 1 ATOM 3557 N N . GLU A 1 456 ? 62.974 66.292 -0.908 1.00 11.70 ? 456 GLU A N 1 ATOM 3558 C CA . GLU A 1 456 ? 62.267 67.246 -0.063 1.00 12.28 ? 456 GLU A CA 1 ATOM 3559 C C . GLU A 1 456 ? 61.112 67.903 -0.816 1.00 12.17 ? 456 GLU A C 1 ATOM 3560 O O . GLU A 1 456 ? 59.977 67.953 -0.309 1.00 11.37 ? 456 GLU A O 1 ATOM 3561 C CB . GLU A 1 456 ? 63.238 68.328 0.447 1.00 15.31 ? 456 GLU A CB 1 ATOM 3562 C CG . GLU A 1 456 ? 62.612 69.384 1.358 1.00 19.39 ? 456 GLU A CG 1 ATOM 3563 C CD . GLU A 1 456 ? 63.498 70.624 1.538 1.00 22.04 ? 456 GLU A CD 1 ATOM 3564 O OE1 . GLU A 1 456 ? 64.735 70.516 1.398 1.00 24.38 ? 456 GLU A OE1 1 ATOM 3565 O OE2 . GLU A 1 456 ? 62.958 71.709 1.824 1.00 24.32 ? 456 GLU A OE2 1 ATOM 3566 N N . ARG A 1 457 ? 61.389 68.416 -2.017 1.00 10.47 ? 457 ARG A N 1 ATOM 3567 C CA . ARG A 1 457 ? 60.335 69.084 -2.773 1.00 10.18 ? 457 ARG A CA 1 ATOM 3568 C C . ARG A 1 457 ? 59.247 68.103 -3.200 1.00 9.37 ? 457 ARG A C 1 ATOM 3569 O O . ARG A 1 457 ? 58.078 68.450 -3.163 1.00 8.40 ? 457 ARG A O 1 ATOM 3570 C CB . ARG A 1 457 ? 60.906 69.808 -4.005 1.00 11.84 ? 457 ARG A CB 1 ATOM 3571 C CG . ARG A 1 457 ? 61.186 71.327 -3.787 1.00 14.18 ? 457 ARG A CG 1 ATOM 3572 C CD . ARG A 1 457 ? 62.133 71.587 -2.610 1.00 18.03 ? 457 ARG A CD 1 ATOM 3573 N NE . ARG A 1 457 ? 62.412 73.014 -2.375 1.00 19.18 ? 457 ARG A NE 1 ATOM 3574 C CZ . ARG A 1 457 ? 63.325 73.745 -3.034 1.00 22.43 ? 457 ARG A CZ 1 ATOM 3575 N NH1 . ARG A 1 457 ? 64.091 73.212 -4.002 1.00 20.60 ? 457 ARG A NH1 1 ATOM 3576 N NH2 . ARG A 1 457 ? 63.489 75.031 -2.703 1.00 21.79 ? 457 ARG A NH2 1 ATOM 3577 N N . LEU A 1 458 ? 59.635 66.885 -3.577 1.00 7.71 ? 458 LEU A N 1 ATOM 3578 C CA . LEU A 1 458 ? 58.642 65.891 -3.997 1.00 8.29 ? 458 LEU A CA 1 ATOM 3579 C C . LEU A 1 458 ? 57.749 65.458 -2.825 1.00 9.04 ? 458 LEU A C 1 ATOM 3580 O O . LEU A 1 458 ? 56.533 65.276 -2.984 1.00 9.10 ? 458 LEU A O 1 ATOM 3581 C CB . LEU A 1 458 ? 59.322 64.658 -4.593 1.00 7.12 ? 458 LEU A CB 1 ATOM 3582 C CG . LEU A 1 458 ? 59.983 64.932 -5.958 1.00 7.60 ? 458 LEU A CG 1 ATOM 3583 C CD1 . LEU A 1 458 ? 60.712 63.660 -6.478 1.00 6.93 ? 458 LEU A CD1 1 ATOM 3584 C CD2 . LEU A 1 458 ? 58.877 65.367 -6.962 1.00 5.60 ? 458 LEU A CD2 1 ATOM 3585 N N . GLU A 1 459 ? 58.339 65.273 -1.655 1.00 8.49 ? 459 GLU A N 1 ATOM 3586 C CA . GLU A 1 459 ? 57.546 64.877 -0.509 1.00 9.28 ? 459 GLU A CA 1 ATOM 3587 C C . GLU A 1 459 ? 56.513 65.963 -0.179 1.00 9.82 ? 459 GLU A C 1 ATOM 3588 O O . GLU A 1 459 ? 55.344 65.674 0.115 1.00 8.48 ? 459 GLU A O 1 ATOM 3589 C CB . GLU A 1 459 ? 58.435 64.645 0.711 1.00 11.44 ? 459 GLU A CB 1 ATOM 3590 C CG . GLU A 1 459 ? 57.633 64.277 1.973 1.00 15.47 ? 459 GLU A CG 1 ATOM 3591 C CD . GLU A 1 459 ? 58.505 63.648 3.061 1.00 17.30 ? 459 GLU A CD 1 ATOM 3592 O OE1 . GLU A 1 459 ? 59.167 64.410 3.764 1.00 17.29 ? 459 GLU A OE1 1 ATOM 3593 O OE2 . GLU A 1 459 ? 58.536 62.395 3.193 1.00 19.39 ? 459 GLU A OE2 1 ATOM 3594 N N . GLN A 1 460 ? 56.934 67.226 -0.216 1.00 10.31 ? 460 GLN A N 1 ATOM 3595 C CA . GLN A 1 460 ? 55.984 68.297 0.076 1.00 11.29 ? 460 GLN A CA 1 ATOM 3596 C C . GLN A 1 460 ? 54.858 68.297 -0.984 1.00 11.19 ? 460 GLN A C 1 ATOM 3597 O O . GLN A 1 460 ? 53.685 68.454 -0.651 1.00 9.22 ? 460 GLN A O 1 ATOM 3598 C CB . GLN A 1 460 ? 56.703 69.638 0.061 1.00 14.90 ? 460 GLN A CB 1 ATOM 3599 C CG . GLN A 1 460 ? 55.781 70.843 0.015 1.00 17.77 ? 460 GLN A CG 1 ATOM 3600 C CD . GLN A 1 460 ? 56.553 72.106 -0.256 1.00 19.35 ? 460 GLN A CD 1 ATOM 3601 O OE1 . GLN A 1 460 ? 57.535 72.092 -0.994 1.00 23.62 ? 460 GLN A OE1 1 ATOM 3602 N NE2 . GLN A 1 460 ? 56.119 73.200 0.325 1.00 21.45 ? 460 GLN A NE2 1 ATOM 3603 N N . ALA A 1 461 ? 55.207 68.103 -2.261 1.00 10.22 ? 461 ALA A N 1 ATOM 3604 C CA . ALA A 1 461 ? 54.147 68.135 -3.272 1.00 9.08 ? 461 ALA A CA 1 ATOM 3605 C C . ALA A 1 461 ? 53.176 66.962 -3.113 1.00 8.94 ? 461 ALA A C 1 ATOM 3606 O O . ALA A 1 461 ? 51.964 67.157 -3.234 1.00 7.97 ? 461 ALA A O 1 ATOM 3607 C CB . ALA A 1 461 ? 54.732 68.139 -4.683 1.00 8.97 ? 461 ALA A CB 1 ATOM 3608 N N . ARG A 1 462 ? 53.703 65.754 -2.850 1.00 7.45 ? 462 ARG A N 1 ATOM 3609 C CA . ARG A 1 462 ? 52.827 64.583 -2.676 1.00 9.05 ? 462 ARG A CA 1 ATOM 3610 C C . ARG A 1 462 ? 51.880 64.793 -1.484 1.00 10.70 ? 462 ARG A C 1 ATOM 3611 O O . ARG A 1 462 ? 50.698 64.371 -1.508 1.00 9.26 ? 462 ARG A O 1 ATOM 3612 C CB . ARG A 1 462 ? 53.645 63.282 -2.415 1.00 8.43 ? 462 ARG A CB 1 ATOM 3613 C CG . ARG A 1 462 ? 54.420 62.714 -3.632 1.00 6.37 ? 462 ARG A CG 1 ATOM 3614 C CD . ARG A 1 462 ? 54.846 61.256 -3.364 1.00 6.11 ? 462 ARG A CD 1 ATOM 3615 N NE . ARG A 1 462 ? 55.758 61.211 -2.227 1.00 8.68 ? 462 ARG A NE 1 ATOM 3616 C CZ . ARG A 1 462 ? 57.076 61.413 -2.309 1.00 10.44 ? 462 ARG A CZ 1 ATOM 3617 N NH1 . ARG A 1 462 ? 57.669 61.659 -3.489 1.00 7.97 ? 462 ARG A NH1 1 ATOM 3618 N NH2 . ARG A 1 462 ? 57.811 61.407 -1.199 1.00 9.35 ? 462 ARG A NH2 1 ATOM 3619 N N . ARG A 1 463 ? 52.421 65.384 -0.409 1.00 9.80 ? 463 ARG A N 1 ATOM 3620 C CA . ARG A 1 463 ? 51.619 65.625 0.791 1.00 10.01 ? 463 ARG A CA 1 ATOM 3621 C C . ARG A 1 463 ? 50.520 66.685 0.661 1.00 9.41 ? 463 ARG A C 1 ATOM 3622 O O . ARG A 1 463 ? 49.438 66.495 1.219 1.00 8.19 ? 463 ARG A O 1 ATOM 3623 C CB . ARG A 1 463 ? 52.522 65.924 2.006 1.00 10.31 ? 463 ARG A CB 1 ATOM 3624 C CG . ARG A 1 463 ? 53.228 64.630 2.456 1.00 11.65 ? 463 ARG A CG 1 ATOM 3625 C CD . ARG A 1 463 ? 54.301 64.793 3.531 1.00 11.26 ? 463 ARG A CD 1 ATOM 3626 N NE . ARG A 1 463 ? 54.747 63.455 3.942 1.00 13.42 ? 463 ARG A NE 1 ATOM 3627 C CZ . ARG A 1 463 ? 55.491 63.207 5.021 1.00 15.52 ? 463 ARG A CZ 1 ATOM 3628 N NH1 . ARG A 1 463 ? 55.878 64.221 5.786 1.00 13.88 ? 463 ARG A NH1 1 ATOM 3629 N NH2 . ARG A 1 463 ? 55.809 61.947 5.351 1.00 15.09 ? 463 ARG A NH2 1 ATOM 3630 N N . GLU A 1 464 ? 50.788 67.785 -0.043 1.00 8.74 ? 464 GLU A N 1 ATOM 3631 C CA . GLU A 1 464 ? 49.754 68.796 -0.209 1.00 9.83 ? 464 GLU A CA 1 ATOM 3632 C C . GLU A 1 464 ? 48.678 68.249 -1.154 1.00 8.89 ? 464 GLU A C 1 ATOM 3633 O O . GLU A 1 464 ? 47.513 68.478 -0.915 1.00 9.95 ? 464 GLU A O 1 ATOM 3634 C CB . GLU A 1 464 ? 50.320 70.109 -0.758 1.00 10.50 ? 464 GLU A CB 1 ATOM 3635 C CG . GLU A 1 464 ? 51.513 70.657 0.032 1.00 13.35 ? 464 GLU A CG 1 ATOM 3636 C CD . GLU A 1 464 ? 51.173 71.054 1.463 1.00 14.18 ? 464 GLU A CD 1 ATOM 3637 O OE1 . GLU A 1 464 ? 50.124 70.657 2.001 1.00 14.03 ? 464 GLU A OE1 1 ATOM 3638 O OE2 . GLU A 1 464 ? 51.987 71.761 2.070 1.00 16.85 ? 464 GLU A OE2 1 ATOM 3639 N N . LEU A 1 465 ? 49.054 67.547 -2.225 1.00 7.74 ? 465 LEU A N 1 ATOM 3640 C CA . LEU A 1 465 ? 48.031 66.955 -3.113 1.00 7.25 ? 465 LEU A CA 1 ATOM 3641 C C . LEU A 1 465 ? 47.250 65.868 -2.331 1.00 7.07 ? 465 LEU A C 1 ATOM 3642 O O . LEU A 1 465 ? 46.031 65.762 -2.448 1.00 7.95 ? 465 LEU A O 1 ATOM 3643 C CB . LEU A 1 465 ? 48.674 66.314 -4.354 1.00 6.99 ? 465 LEU A CB 1 ATOM 3644 C CG . LEU A 1 465 ? 47.695 65.612 -5.317 1.00 6.14 ? 465 LEU A CG 1 ATOM 3645 C CD1 . LEU A 1 465 ? 46.597 66.593 -5.754 1.00 5.51 ? 465 LEU A CD1 1 ATOM 3646 C CD2 . LEU A 1 465 ? 48.468 65.080 -6.564 1.00 5.04 ? 465 LEU A CD2 1 ATOM 3647 N N . SER A 1 466 ? 47.955 65.063 -1.526 1.00 6.63 ? 466 SER A N 1 ATOM 3648 C CA . SER A 1 466 ? 47.300 64.016 -0.740 1.00 5.57 ? 466 SER A CA 1 ATOM 3649 C C . SER A 1 466 ? 46.309 64.643 0.236 1.00 7.00 ? 466 SER A C 1 ATOM 3650 O O . SER A 1 466 ? 45.164 64.167 0.396 1.00 5.43 ? 466 SER A O 1 ATOM 3651 C CB . SER A 1 466 ? 48.328 63.212 0.039 1.00 4.71 ? 466 SER A CB 1 ATOM 3652 O OG . SER A 1 466 ? 49.077 62.393 -0.844 1.00 6.20 ? 466 SER A OG 1 ATOM 3653 N N . LEU A 1 467 ? 46.737 65.726 0.883 1.00 6.50 ? 467 LEU A N 1 ATOM 3654 C CA . LEU A 1 467 ? 45.854 66.379 1.827 1.00 8.12 ? 467 LEU A CA 1 ATOM 3655 C C . LEU A 1 467 ? 44.542 66.826 1.154 1.00 8.50 ? 467 LEU A C 1 ATOM 3656 O O . LEU A 1 467 ? 43.451 66.673 1.719 1.00 6.88 ? 467 LEU A O 1 ATOM 3657 C CB . LEU A 1 467 ? 46.552 67.592 2.448 1.00 8.34 ? 467 LEU A CB 1 ATOM 3658 C CG . LEU A 1 467 ? 45.733 68.319 3.503 1.00 12.26 ? 467 LEU A CG 1 ATOM 3659 C CD1 . LEU A 1 467 ? 45.720 67.453 4.815 1.00 12.07 ? 467 LEU A CD1 1 ATOM 3660 C CD2 . LEU A 1 467 ? 46.348 69.725 3.762 1.00 10.52 ? 467 LEU A CD2 1 ATOM 3661 N N . PHE A 1 468 ? 44.651 67.381 -0.046 1.00 8.18 ? 468 PHE A N 1 ATOM 3662 C CA . PHE A 1 468 ? 43.470 67.870 -0.763 1.00 9.57 ? 468 PHE A CA 1 ATOM 3663 C C . PHE A 1 468 ? 42.490 66.755 -1.141 1.00 9.51 ? 468 PHE A C 1 ATOM 3664 O O . PHE A 1 468 ? 41.354 67.038 -1.521 1.00 10.21 ? 468 PHE A O 1 ATOM 3665 C CB . PHE A 1 468 ? 43.886 68.647 -2.033 1.00 9.85 ? 468 PHE A CB 1 ATOM 3666 C CG . PHE A 1 468 ? 42.759 69.448 -2.644 1.00 10.97 ? 468 PHE A CG 1 ATOM 3667 C CD1 . PHE A 1 468 ? 42.044 70.369 -1.863 1.00 10.58 ? 468 PHE A CD1 1 ATOM 3668 C CD2 . PHE A 1 468 ? 42.366 69.250 -3.959 1.00 9.05 ? 468 PHE A CD2 1 ATOM 3669 C CE1 . PHE A 1 468 ? 40.926 71.089 -2.403 1.00 10.24 ? 468 PHE A CE1 1 ATOM 3670 C CE2 . PHE A 1 468 ? 41.270 69.951 -4.500 1.00 9.75 ? 468 PHE A CE2 1 ATOM 3671 C CZ . PHE A 1 468 ? 40.546 70.879 -3.708 1.00 9.05 ? 468 PHE A CZ 1 ATOM 3672 N N . GLN A 1 469 ? 42.917 65.492 -1.061 1.00 8.39 ? 469 GLN A N 1 ATOM 3673 C CA . GLN A 1 469 ? 42.007 64.394 -1.392 1.00 8.38 ? 469 GLN A CA 1 ATOM 3674 C C . GLN A 1 469 ? 40.963 64.189 -0.289 1.00 8.58 ? 469 GLN A C 1 ATOM 3675 O O . GLN A 1 469 ? 40.006 63.428 -0.458 1.00 9.24 ? 469 GLN A O 1 ATOM 3676 C CB . GLN A 1 469 ? 42.795 63.089 -1.582 1.00 8.62 ? 469 GLN A CB 1 ATOM 3677 C CG . GLN A 1 469 ? 43.864 63.170 -2.716 1.00 6.91 ? 469 GLN A CG 1 ATOM 3678 C CD . GLN A 1 469 ? 43.296 63.752 -4.000 1.00 5.04 ? 469 GLN A CD 1 ATOM 3679 O OE1 . GLN A 1 469 ? 42.334 63.217 -4.585 1.00 5.74 ? 469 GLN A OE1 1 ATOM 3680 N NE2 . GLN A 1 469 ? 43.867 64.852 -4.432 1.00 7.02 ? 469 GLN A NE2 1 ATOM 3681 N N . HIS A 1 470 ? 41.182 64.856 0.844 1.00 7.38 ? 470 HIS A N 1 ATOM 3682 C CA . HIS A 1 470 ? 40.292 64.783 1.980 1.00 7.20 ? 470 HIS A CA 1 ATOM 3683 C C . HIS A 1 470 ? 38.850 65.019 1.523 1.00 6.39 ? 470 HIS A C 1 ATOM 3684 O O . HIS A 1 470 ? 38.615 65.741 0.551 1.00 5.75 ? 470 HIS A O 1 ATOM 3685 C CB . HIS A 1 470 ? 40.724 65.818 3.049 1.00 6.21 ? 470 HIS A CB 1 ATOM 3686 C CG . HIS A 1 470 ? 39.717 66.036 4.126 1.00 8.61 ? 470 HIS A CG 1 ATOM 3687 N ND1 . HIS A 1 470 ? 39.121 64.997 4.816 1.00 8.23 ? 470 HIS A ND1 1 ATOM 3688 C CD2 . HIS A 1 470 ? 39.211 67.178 4.655 1.00 8.15 ? 470 HIS A CD2 1 ATOM 3689 C CE1 . HIS A 1 470 ? 38.291 65.495 5.716 1.00 8.94 ? 470 HIS A CE1 1 ATOM 3690 N NE2 . HIS A 1 470 ? 38.324 66.814 5.639 1.00 8.57 ? 470 HIS A NE2 1 ATOM 3691 N N . HIS A 1 471 ? 37.896 64.410 2.227 1.00 6.27 ? 471 HIS A N 1 ATOM 3692 C CA . HIS A 1 471 ? 36.492 64.575 1.860 1.00 7.64 ? 471 HIS A CA 1 ATOM 3693 C C . HIS A 1 471 ? 35.861 65.980 2.117 1.00 9.39 ? 471 HIS A C 1 ATOM 3694 O O . HIS A 1 471 ? 34.639 66.137 1.987 1.00 8.95 ? 471 HIS A O 1 ATOM 3695 C CB . HIS A 1 471 ? 35.639 63.451 2.472 1.00 8.52 ? 471 HIS A CB 1 ATOM 3696 C CG . HIS A 1 471 ? 35.771 63.320 3.956 1.00 7.85 ? 471 HIS A CG 1 ATOM 3697 N ND1 . HIS A 1 471 ? 36.771 62.584 4.559 1.00 8.73 ? 471 HIS A ND1 1 ATOM 3698 C CD2 . HIS A 1 471 ? 35.055 63.883 4.962 1.00 8.30 ? 471 HIS A CD2 1 ATOM 3699 C CE1 . HIS A 1 471 ? 36.673 62.710 5.873 1.00 8.84 ? 471 HIS A CE1 1 ATOM 3700 N NE2 . HIS A 1 471 ? 35.643 63.493 6.141 1.00 8.25 ? 471 HIS A NE2 1 ATOM 3701 N N . ASP A 1 472 ? 36.682 66.975 2.515 1.00 9.29 ? 472 ASP A N 1 ATOM 3702 C CA . ASP A 1 472 ? 36.211 68.374 2.576 1.00 8.55 ? 472 ASP A CA 1 ATOM 3703 C C . ASP A 1 472 ? 37.187 69.217 1.727 1.00 9.51 ? 472 ASP A C 1 ATOM 3704 O O . ASP A 1 472 ? 37.117 70.457 1.705 1.00 10.52 ? 472 ASP A O 1 ATOM 3705 C CB . ASP A 1 472 ? 36.174 68.936 3.987 1.00 9.99 ? 472 ASP A CB 1 ATOM 3706 C CG . ASP A 1 472 ? 35.129 68.252 4.857 1.00 9.61 ? 472 ASP A CG 1 ATOM 3707 O OD1 . ASP A 1 472 ? 33.933 68.286 4.489 1.00 10.78 ? 472 ASP A OD1 1 ATOM 3708 O OD2 . ASP A 1 472 ? 35.518 67.688 5.889 1.00 9.25 ? 472 ASP A OD2 1 ATOM 3709 N N . GLY A 1 473 ? 38.106 68.527 1.056 1.00 8.46 ? 473 GLY A N 1 ATOM 3710 C CA . GLY A 1 473 ? 39.091 69.184 0.209 1.00 8.53 ? 473 GLY A CA 1 ATOM 3711 C C . GLY A 1 473 ? 38.552 69.348 -1.197 1.00 8.86 ? 473 GLY A C 1 ATOM 3712 O O . GLY A 1 473 ? 37.852 70.326 -1.508 1.00 8.08 ? 473 GLY A O 1 ATOM 3713 N N . ILE A 1 474 ? 38.860 68.375 -2.055 1.00 7.90 ? 474 ILE A N 1 ATOM 3714 C CA . ILE A 1 474 ? 38.426 68.400 -3.439 1.00 7.69 ? 474 ILE A CA 1 ATOM 3715 C C . ILE A 1 474 ? 36.877 68.482 -3.575 1.00 8.55 ? 474 ILE A C 1 ATOM 3716 O O . ILE A 1 474 ? 36.356 68.929 -4.593 1.00 8.33 ? 474 ILE A O 1 ATOM 3717 C CB . ILE A 1 474 ? 38.998 67.155 -4.190 1.00 8.57 ? 474 ILE A CB 1 ATOM 3718 C CG1 . ILE A 1 474 ? 38.717 67.268 -5.686 1.00 8.04 ? 474 ILE A CG1 1 ATOM 3719 C CG2 . ILE A 1 474 ? 38.413 65.856 -3.584 1.00 8.68 ? 474 ILE A CG2 1 ATOM 3720 C CD1 . ILE A 1 474 ? 39.297 66.136 -6.477 1.00 10.23 ? 474 ILE A CD1 1 ATOM 3721 N N . THR A 1 475 ? 36.156 68.081 -2.527 1.00 9.05 ? 475 THR A N 1 ATOM 3722 C CA . THR A 1 475 ? 34.687 68.112 -2.519 1.00 8.94 ? 475 THR A CA 1 ATOM 3723 C C . THR A 1 475 ? 34.136 69.553 -2.549 1.00 9.82 ? 475 THR A C 1 ATOM 3724 O O . THR A 1 475 ? 32.973 69.770 -2.923 1.00 11.65 ? 475 THR A O 1 ATOM 3725 C CB . THR A 1 475 ? 34.141 67.484 -1.238 1.00 9.52 ? 475 THR A CB 1 ATOM 3726 O OG1 . THR A 1 475 ? 34.692 68.216 -0.130 1.00 10.10 ? 475 THR A OG1 1 ATOM 3727 C CG2 . THR A 1 475 ? 34.526 65.958 -1.137 1.00 6.32 ? 475 THR A CG2 1 ATOM 3728 N N . GLY A 1 476 ? 34.955 70.524 -2.179 1.00 9.91 ? 476 GLY A N 1 ATOM 3729 C CA . GLY A 1 476 ? 34.472 71.902 -2.156 1.00 10.07 ? 476 GLY A CA 1 ATOM 3730 C C . GLY A 1 476 ? 33.501 72.117 -0.984 1.00 10.07 ? 476 GLY A C 1 ATOM 3731 O O . GLY A 1 476 ? 32.626 72.957 -1.075 1.00 10.70 ? 476 GLY A O 1 ATOM 3732 N N . THR A 1 477 ? 33.646 71.375 0.116 1.00 9.54 ? 477 THR A N 1 ATOM 3733 C CA . THR A 1 477 ? 32.736 71.513 1.259 1.00 9.39 ? 477 THR A CA 1 ATOM 3734 C C . THR A 1 477 ? 33.376 72.128 2.525 1.00 10.77 ? 477 THR A C 1 ATOM 3735 O O . THR A 1 477 ? 32.876 71.916 3.648 1.00 10.75 ? 477 THR A O 1 ATOM 3736 C CB . THR A 1 477 ? 32.095 70.134 1.649 1.00 9.11 ? 477 THR A CB 1 ATOM 3737 O OG1 . THR A 1 477 ? 33.134 69.185 1.915 1.00 10.19 ? 477 THR A OG1 1 ATOM 3738 C CG2 . THR A 1 477 ? 31.211 69.574 0.514 1.00 8.58 ? 477 THR A CG2 1 ATOM 3739 N N . ALA A 1 478 ? 34.471 72.872 2.352 1.00 10.44 ? 478 ALA A N 1 ATOM 3740 C CA . ALA A 1 478 ? 35.139 73.503 3.492 1.00 11.76 ? 478 ALA A CA 1 ATOM 3741 C C . ALA A 1 478 ? 34.836 75.005 3.560 1.00 11.94 ? 478 ALA A C 1 ATOM 3742 O O . ALA A 1 478 ? 34.322 75.608 2.607 1.00 10.58 ? 478 ALA A O 1 ATOM 3743 C CB . ALA A 1 478 ? 36.640 73.286 3.401 1.00 9.30 ? 478 ALA A CB 1 ATOM 3744 N N . LYS A 1 479 ? 35.139 75.620 4.695 1.00 13.32 ? 479 LYS A N 1 ATOM 3745 C CA . LYS A 1 479 ? 34.883 77.052 4.806 1.00 13.06 ? 479 LYS A CA 1 ATOM 3746 C C . LYS A 1 479 ? 35.844 77.803 3.900 1.00 12.10 ? 479 LYS A C 1 ATOM 3747 O O . LYS A 1 479 ? 36.906 77.303 3.544 1.00 9.51 ? 479 LYS A O 1 ATOM 3748 C CB . LYS A 1 479 ? 35.038 77.539 6.268 1.00 15.35 ? 479 LYS A CB 1 ATOM 3749 C CG . LYS A 1 479 ? 33.848 77.081 7.165 1.00 17.18 ? 479 LYS A CG 1 ATOM 3750 C CD . LYS A 1 479 ? 33.684 77.924 8.433 1.00 21.08 ? 479 LYS A CD 1 ATOM 3751 C CE . LYS A 1 479 ? 32.614 79.004 8.259 1.00 22.32 ? 479 LYS A CE 1 ATOM 3752 N NZ . LYS A 1 479 ? 31.268 78.467 8.651 1.00 21.78 ? 479 LYS A NZ 1 ATOM 3753 N N . THR A 1 480 ? 35.468 79.028 3.563 1.00 12.59 ? 480 THR A N 1 ATOM 3754 C CA . THR A 1 480 ? 36.247 79.886 2.689 1.00 12.45 ? 480 THR A CA 1 ATOM 3755 C C . THR A 1 480 ? 37.725 79.995 3.003 1.00 13.58 ? 480 THR A C 1 ATOM 3756 O O . THR A 1 480 ? 38.575 79.787 2.119 1.00 13.58 ? 480 THR A O 1 ATOM 3757 C CB . THR A 1 480 ? 35.635 81.307 2.704 1.00 14.30 ? 480 THR A CB 1 ATOM 3758 O OG1 . THR A 1 480 ? 34.274 81.209 2.289 1.00 15.53 ? 480 THR A OG1 1 ATOM 3759 C CG2 . THR A 1 480 ? 36.404 82.288 1.733 1.00 12.71 ? 480 THR A CG2 1 ATOM 3760 N N . HIS A 1 481 ? 38.065 80.317 4.248 1.00 12.16 ? 481 HIS A N 1 ATOM 3761 C CA . HIS A 1 481 ? 39.482 80.459 4.549 1.00 11.84 ? 481 HIS A CA 1 ATOM 3762 C C . HIS A 1 481 ? 40.225 79.111 4.495 1.00 12.10 ? 481 HIS A C 1 ATOM 3763 O O . HIS A 1 481 ? 41.448 79.085 4.329 1.00 11.28 ? 481 HIS A O 1 ATOM 3764 C CB . HIS A 1 481 ? 39.696 81.181 5.908 1.00 12.27 ? 481 HIS A CB 1 ATOM 3765 C CG . HIS A 1 481 ? 39.625 80.285 7.108 1.00 12.90 ? 481 HIS A CG 1 ATOM 3766 N ND1 . HIS A 1 481 ? 38.441 79.762 7.586 1.00 14.15 ? 481 HIS A ND1 1 ATOM 3767 C CD2 . HIS A 1 481 ? 40.603 79.786 7.899 1.00 14.05 ? 481 HIS A CD2 1 ATOM 3768 C CE1 . HIS A 1 481 ? 38.697 78.974 8.615 1.00 14.76 ? 481 HIS A CE1 1 ATOM 3769 N NE2 . HIS A 1 481 ? 40.003 78.972 8.825 1.00 13.82 ? 481 HIS A NE2 1 ATOM 3770 N N . VAL A 1 482 ? 39.490 78.002 4.621 1.00 10.50 ? 482 VAL A N 1 ATOM 3771 C CA . VAL A 1 482 ? 40.117 76.666 4.579 1.00 9.69 ? 482 VAL A CA 1 ATOM 3772 C C . VAL A 1 482 ? 40.433 76.335 3.103 1.00 9.17 ? 482 VAL A C 1 ATOM 3773 O O . VAL A 1 482 ? 41.497 75.823 2.795 1.00 10.67 ? 482 VAL A O 1 ATOM 3774 C CB . VAL A 1 482 ? 39.185 75.598 5.242 1.00 8.33 ? 482 VAL A CB 1 ATOM 3775 C CG1 . VAL A 1 482 ? 39.798 74.185 5.132 1.00 6.16 ? 482 VAL A CG1 1 ATOM 3776 C CG2 . VAL A 1 482 ? 38.992 75.958 6.764 1.00 7.82 ? 482 VAL A CG2 1 ATOM 3777 N N . VAL A 1 483 ? 39.504 76.644 2.209 1.00 9.52 ? 483 VAL A N 1 ATOM 3778 C CA . VAL A 1 483 ? 39.682 76.456 0.773 1.00 9.84 ? 483 VAL A CA 1 ATOM 3779 C C . VAL A 1 483 ? 40.923 77.271 0.366 1.00 10.85 ? 483 VAL A C 1 ATOM 3780 O O . VAL A 1 483 ? 41.766 76.816 -0.419 1.00 11.06 ? 483 VAL A O 1 ATOM 3781 C CB . VAL A 1 483 ? 38.417 76.992 0.026 1.00 12.29 ? 483 VAL A CB 1 ATOM 3782 C CG1 . VAL A 1 483 ? 38.639 77.077 -1.491 1.00 12.89 ? 483 VAL A CG1 1 ATOM 3783 C CG2 . VAL A 1 483 ? 37.193 76.067 0.371 1.00 13.96 ? 483 VAL A CG2 1 ATOM 3784 N N . VAL A 1 484 ? 41.062 78.473 0.923 1.00 11.23 ? 484 VAL A N 1 ATOM 3785 C CA . VAL A 1 484 ? 42.217 79.295 0.572 1.00 12.25 ? 484 VAL A CA 1 ATOM 3786 C C . VAL A 1 484 ? 43.491 78.588 0.998 1.00 11.21 ? 484 VAL A C 1 ATOM 3787 O O . VAL A 1 484 ? 44.500 78.555 0.270 1.00 11.59 ? 484 VAL A O 1 ATOM 3788 C CB . VAL A 1 484 ? 42.141 80.671 1.250 1.00 12.20 ? 484 VAL A CB 1 ATOM 3789 C CG1 . VAL A 1 484 ? 43.515 81.384 1.121 1.00 10.94 ? 484 VAL A CG1 1 ATOM 3790 C CG2 . VAL A 1 484 ? 41.014 81.484 0.604 1.00 12.80 ? 484 VAL A CG2 1 ATOM 3791 N N . ASP A 1 485 ? 43.440 77.981 2.175 1.00 12.35 ? 485 ASP A N 1 ATOM 3792 C CA . ASP A 1 485 ? 44.614 77.259 2.691 1.00 10.71 ? 485 ASP A CA 1 ATOM 3793 C C . ASP A 1 485 ? 44.979 76.082 1.770 1.00 10.64 ? 485 ASP A C 1 ATOM 3794 O O . ASP A 1 485 ? 46.159 75.831 1.501 1.00 11.86 ? 485 ASP A O 1 ATOM 3795 C CB . ASP A 1 485 ? 44.329 76.719 4.082 1.00 10.44 ? 485 ASP A CB 1 ATOM 3796 C CG . ASP A 1 485 ? 45.553 76.095 4.716 1.00 11.52 ? 485 ASP A CG 1 ATOM 3797 O OD1 . ASP A 1 485 ? 45.515 74.944 5.155 1.00 11.40 ? 485 ASP A OD1 1 ATOM 3798 O OD2 . ASP A 1 485 ? 46.576 76.776 4.770 1.00 12.35 ? 485 ASP A OD2 1 ATOM 3799 N N . TYR A 1 486 ? 43.988 75.320 1.323 1.00 10.73 ? 486 TYR A N 1 ATOM 3800 C CA . TYR A 1 486 ? 44.285 74.197 0.407 1.00 9.21 ? 486 TYR A CA 1 ATOM 3801 C C . TYR A 1 486 ? 44.901 74.727 -0.899 1.00 9.60 ? 486 TYR A C 1 ATOM 3802 O O . TYR A 1 486 ? 45.789 74.099 -1.485 1.00 9.19 ? 486 TYR A O 1 ATOM 3803 C CB . TYR A 1 486 ? 43.016 73.455 0.049 1.00 9.00 ? 486 TYR A CB 1 ATOM 3804 C CG . TYR A 1 486 ? 42.411 72.658 1.186 1.00 10.74 ? 486 TYR A CG 1 ATOM 3805 C CD1 . TYR A 1 486 ? 41.028 72.634 1.370 1.00 9.99 ? 486 TYR A CD1 1 ATOM 3806 C CD2 . TYR A 1 486 ? 43.209 71.832 2.006 1.00 11.52 ? 486 TYR A CD2 1 ATOM 3807 C CE1 . TYR A 1 486 ? 40.426 71.791 2.335 1.00 11.30 ? 486 TYR A CE1 1 ATOM 3808 C CE2 . TYR A 1 486 ? 42.615 70.986 2.985 1.00 11.07 ? 486 TYR A CE2 1 ATOM 3809 C CZ . TYR A 1 486 ? 41.219 70.979 3.126 1.00 10.61 ? 486 TYR A CZ 1 ATOM 3810 O OH . TYR A 1 486 ? 40.601 70.144 4.005 1.00 11.65 ? 486 TYR A OH 1 ATOM 3811 N N . GLU A 1 487 ? 44.402 75.871 -1.362 1.00 9.60 ? 487 GLU A N 1 ATOM 3812 C CA . GLU A 1 487 ? 44.898 76.462 -2.604 1.00 11.67 ? 487 GLU A CA 1 ATOM 3813 C C . GLU A 1 487 ? 46.367 76.877 -2.464 1.00 13.27 ? 487 GLU A C 1 ATOM 3814 O O . GLU A 1 487 ? 47.181 76.614 -3.338 1.00 12.33 ? 487 GLU A O 1 ATOM 3815 C CB . GLU A 1 487 ? 44.084 77.704 -2.986 1.00 12.47 ? 487 GLU A CB 1 ATOM 3816 C CG . GLU A 1 487 ? 44.455 78.204 -4.370 1.00 15.72 ? 487 GLU A CG 1 ATOM 3817 C CD . GLU A 1 487 ? 43.638 79.398 -4.856 1.00 18.49 ? 487 GLU A CD 1 ATOM 3818 O OE1 . GLU A 1 487 ? 42.463 79.525 -4.451 1.00 19.01 ? 487 GLU A OE1 1 ATOM 3819 O OE2 . GLU A 1 487 ? 44.176 80.188 -5.676 1.00 20.04 ? 487 GLU A OE2 1 ATOM 3820 N N . GLN A 1 488 ? 46.696 77.550 -1.363 1.00 14.46 ? 488 GLN A N 1 ATOM 3821 C CA . GLN A 1 488 ? 48.063 77.998 -1.155 1.00 15.63 ? 488 GLN A CA 1 ATOM 3822 C C . GLN A 1 488 ? 48.985 76.796 -1.046 1.00 14.04 ? 488 GLN A C 1 ATOM 3823 O O . GLN A 1 488 ? 50.088 76.821 -1.571 1.00 14.09 ? 488 GLN A O 1 ATOM 3824 C CB . GLN A 1 488 ? 48.141 78.846 0.120 1.00 18.74 ? 488 GLN A CB 1 ATOM 3825 C CG . GLN A 1 488 ? 47.121 79.976 0.078 1.00 25.52 ? 488 GLN A CG 1 ATOM 3826 C CD . GLN A 1 488 ? 47.282 80.962 1.215 1.00 29.45 ? 488 GLN A CD 1 ATOM 3827 O OE1 . GLN A 1 488 ? 47.445 80.581 2.387 1.00 32.72 ? 488 GLN A OE1 1 ATOM 3828 N NE2 . GLN A 1 488 ? 47.234 82.253 0.875 1.00 32.45 ? 488 GLN A NE2 1 ATOM 3829 N N . ARG A 1 489 ? 48.539 75.754 -0.351 1.00 11.94 ? 489 ARG A N 1 ATOM 3830 C CA . ARG A 1 489 ? 49.344 74.540 -0.220 1.00 10.69 ? 489 ARG A CA 1 ATOM 3831 C C . ARG A 1 489 ? 49.572 73.941 -1.614 1.00 11.29 ? 489 ARG A C 1 ATOM 3832 O O . ARG A 1 489 ? 50.707 73.640 -1.992 1.00 9.70 ? 489 ARG A O 1 ATOM 3833 C CB . ARG A 1 489 ? 48.643 73.506 0.670 1.00 11.46 ? 489 ARG A CB 1 ATOM 3834 C CG . ARG A 1 489 ? 48.612 73.870 2.158 1.00 9.94 ? 489 ARG A CG 1 ATOM 3835 C CD . ARG A 1 489 ? 47.748 72.839 2.919 1.00 12.75 ? 489 ARG A CD 1 ATOM 3836 N NE . ARG A 1 489 ? 47.774 73.031 4.366 1.00 11.50 ? 489 ARG A NE 1 ATOM 3837 C CZ . ARG A 1 489 ? 48.667 72.470 5.187 1.00 13.97 ? 489 ARG A CZ 1 ATOM 3838 N NH1 . ARG A 1 489 ? 49.603 71.662 4.697 1.00 9.50 ? 489 ARG A NH1 1 ATOM 3839 N NH2 . ARG A 1 489 ? 48.661 72.771 6.493 1.00 11.83 ? 489 ARG A NH2 1 ATOM 3840 N N . MET A 1 490 ? 48.507 73.814 -2.404 1.00 10.85 ? 490 MET A N 1 ATOM 3841 C CA . MET A 1 490 ? 48.686 73.254 -3.745 1.00 10.47 ? 490 MET A CA 1 ATOM 3842 C C . MET A 1 490 ? 49.570 74.153 -4.585 1.00 10.14 ? 490 MET A C 1 ATOM 3843 O O . MET A 1 490 ? 50.367 73.665 -5.359 1.00 9.72 ? 490 MET A O 1 ATOM 3844 C CB . MET A 1 490 ? 47.335 72.991 -4.428 1.00 8.42 ? 490 MET A CB 1 ATOM 3845 C CG . MET A 1 490 ? 46.564 71.846 -3.758 1.00 9.17 ? 490 MET A CG 1 ATOM 3846 S SD . MET A 1 490 ? 45.239 71.204 -4.841 1.00 13.60 ? 490 MET A SD 1 ATOM 3847 C CE . MET A 1 490 ? 43.900 72.425 -4.523 1.00 15.16 ? 490 MET A CE 1 ATOM 3848 N N . GLN A 1 491 ? 49.454 75.463 -4.415 1.00 11.89 ? 491 GLN A N 1 ATOM 3849 C CA . GLN A 1 491 ? 50.302 76.383 -5.173 1.00 14.15 ? 491 GLN A CA 1 ATOM 3850 C C . GLN A 1 491 ? 51.794 76.129 -4.869 1.00 13.81 ? 491 GLN A C 1 ATOM 3851 O O . GLN A 1 491 ? 52.644 76.101 -5.766 1.00 12.48 ? 491 GLN A O 1 ATOM 3852 C CB . GLN A 1 491 ? 49.936 77.815 -4.830 1.00 18.48 ? 491 GLN A CB 1 ATOM 3853 C CG . GLN A 1 491 ? 50.584 78.833 -5.715 1.00 23.63 ? 491 GLN A CG 1 ATOM 3854 C CD . GLN A 1 491 ? 50.058 78.769 -7.143 1.00 27.66 ? 491 GLN A CD 1 ATOM 3855 O OE1 . GLN A 1 491 ? 50.686 78.180 -8.042 1.00 30.34 ? 491 GLN A OE1 1 ATOM 3856 N NE2 . GLN A 1 491 ? 48.887 79.371 -7.358 1.00 30.42 ? 491 GLN A NE2 1 ATOM 3857 N N . GLU A 1 492 ? 52.114 75.928 -3.597 1.00 14.12 ? 492 GLU A N 1 ATOM 3858 C CA . GLU A 1 492 ? 53.486 75.647 -3.235 1.00 15.59 ? 492 GLU A CA 1 ATOM 3859 C C . GLU A 1 492 ? 53.865 74.291 -3.836 1.00 12.93 ? 492 GLU A C 1 ATOM 3860 O O . GLU A 1 492 ? 54.997 74.112 -4.287 1.00 11.91 ? 492 GLU A O 1 ATOM 3861 C CB . GLU A 1 492 ? 53.658 75.646 -1.723 1.00 18.54 ? 492 GLU A CB 1 ATOM 3862 C CG . GLU A 1 492 ? 53.545 77.048 -1.097 1.00 23.98 ? 492 GLU A CG 1 ATOM 3863 C CD . GLU A 1 492 ? 54.498 78.073 -1.755 1.00 27.94 ? 492 GLU A CD 1 ATOM 3864 O OE1 . GLU A 1 492 ? 54.019 79.177 -2.116 1.00 31.12 ? 492 GLU A OE1 1 ATOM 3865 O OE2 . GLU A 1 492 ? 55.716 77.791 -1.913 1.00 30.32 ? 492 GLU A OE2 1 ATOM 3866 N N . ALA A 1 493 ? 52.911 73.354 -3.869 1.00 10.61 ? 493 ALA A N 1 ATOM 3867 C CA . ALA A 1 493 ? 53.182 72.029 -4.452 1.00 9.32 ? 493 ALA A CA 1 ATOM 3868 C C . ALA A 1 493 ? 53.490 72.168 -5.961 1.00 9.38 ? 493 ALA A C 1 ATOM 3869 O O . ALA A 1 493 ? 54.393 71.506 -6.487 1.00 9.46 ? 493 ALA A O 1 ATOM 3870 C CB . ALA A 1 493 ? 51.987 71.102 -4.245 1.00 7.55 ? 493 ALA A CB 1 ATOM 3871 N N . LEU A 1 494 ? 52.743 73.009 -6.665 1.00 8.50 ? 494 LEU A N 1 ATOM 3872 C CA . LEU A 1 494 ? 53.014 73.195 -8.097 1.00 9.93 ? 494 LEU A CA 1 ATOM 3873 C C . LEU A 1 494 ? 54.438 73.761 -8.301 1.00 9.88 ? 494 LEU A C 1 ATOM 3874 O O . LEU A 1 494 ? 55.175 73.285 -9.150 1.00 9.85 ? 494 LEU A O 1 ATOM 3875 C CB . LEU A 1 494 ? 51.957 74.118 -8.722 1.00 10.52 ? 494 LEU A CB 1 ATOM 3876 C CG . LEU A 1 494 ? 50.575 73.453 -8.844 1.00 10.17 ? 494 LEU A CG 1 ATOM 3877 C CD1 . LEU A 1 494 ? 49.487 74.490 -9.237 1.00 11.24 ? 494 LEU A CD1 1 ATOM 3878 C CD2 . LEU A 1 494 ? 50.685 72.372 -9.892 1.00 9.99 ? 494 LEU A CD2 1 ATOM 3879 N N . LYS A 1 495 ? 54.816 74.775 -7.531 1.00 10.38 ? 495 LYS A N 1 ATOM 3880 C CA . LYS A 1 495 ? 56.164 75.350 -7.629 1.00 12.19 ? 495 LYS A CA 1 ATOM 3881 C C . LYS A 1 495 ? 57.255 74.307 -7.325 1.00 12.45 ? 495 LYS A C 1 ATOM 3882 O O . LYS A 1 495 ? 58.307 74.279 -7.985 1.00 10.63 ? 495 LYS A O 1 ATOM 3883 C CB . LYS A 1 495 ? 56.311 76.531 -6.661 1.00 15.34 ? 495 LYS A CB 1 ATOM 3884 C CG . LYS A 1 495 ? 55.466 77.727 -7.078 1.00 19.97 ? 495 LYS A CG 1 ATOM 3885 C CD . LYS A 1 495 ? 55.971 79.035 -6.477 1.00 24.68 ? 495 LYS A CD 1 ATOM 3886 C CE . LYS A 1 495 ? 55.809 79.082 -4.979 1.00 28.34 ? 495 LYS A CE 1 ATOM 3887 N NZ . LYS A 1 495 ? 54.378 79.181 -4.529 1.00 32.79 ? 495 LYS A NZ 1 ATOM 3888 N N . ALA A 1 496 ? 57.002 73.448 -6.333 1.00 10.54 ? 496 ALA A N 1 ATOM 3889 C CA . ALA A 1 496 ? 57.963 72.403 -5.992 1.00 10.22 ? 496 ALA A CA 1 ATOM 3890 C C . ALA A 1 496 ? 58.136 71.475 -7.224 1.00 10.13 ? 496 ALA A C 1 ATOM 3891 O O . ALA A 1 496 ? 59.266 71.153 -7.619 1.00 9.22 ? 496 ALA A O 1 ATOM 3892 C CB . ALA A 1 496 ? 57.471 71.606 -4.767 1.00 9.80 ? 496 ALA A CB 1 ATOM 3893 N N . CYS A 1 497 ? 57.021 71.054 -7.830 1.00 9.99 ? 497 CYS A N 1 ATOM 3894 C CA . CYS A 1 497 ? 57.069 70.184 -9.023 1.00 9.32 ? 497 CYS A CA 1 ATOM 3895 C C . CYS A 1 497 ? 57.858 70.850 -10.153 1.00 8.56 ? 497 CYS A C 1 ATOM 3896 O O . CYS A 1 497 ? 58.731 70.242 -10.766 1.00 8.81 ? 497 CYS A O 1 ATOM 3897 C CB . CYS A 1 497 ? 55.642 69.852 -9.510 1.00 9.00 ? 497 CYS A CB 1 ATOM 3898 S SG . CYS A 1 497 ? 54.738 68.687 -8.372 1.00 9.19 ? 497 CYS A SG 1 ATOM 3899 N N . GLN A 1 498 ? 57.571 72.115 -10.398 1.00 9.39 ? 498 GLN A N 1 ATOM 3900 C CA . GLN A 1 498 ? 58.269 72.861 -11.451 1.00 10.94 ? 498 GLN A CA 1 ATOM 3901 C C . GLN A 1 498 ? 59.785 72.837 -11.208 1.00 10.27 ? 498 GLN A C 1 ATOM 3902 O O . GLN A 1 498 ? 60.556 72.519 -12.102 1.00 9.22 ? 498 GLN A O 1 ATOM 3903 C CB . GLN A 1 498 ? 57.798 74.314 -11.479 1.00 13.14 ? 498 GLN A CB 1 ATOM 3904 C CG . GLN A 1 498 ? 58.493 75.110 -12.558 1.00 17.84 ? 498 GLN A CG 1 ATOM 3905 C CD . GLN A 1 498 ? 57.996 76.552 -12.695 1.00 21.07 ? 498 GLN A CD 1 ATOM 3906 O OE1 . GLN A 1 498 ? 57.891 77.076 -13.813 1.00 19.97 ? 498 GLN A OE1 1 ATOM 3907 N NE2 . GLN A 1 498 ? 57.711 77.207 -11.556 1.00 22.70 ? 498 GLN A NE2 1 ATOM 3908 N N . MET A 1 499 ? 60.202 73.176 -9.993 1.00 9.76 ? 499 MET A N 1 ATOM 3909 C CA . MET A 1 499 ? 61.626 73.187 -9.667 1.00 10.23 ? 499 MET A CA 1 ATOM 3910 C C . MET A 1 499 ? 62.274 71.830 -9.976 1.00 9.36 ? 499 MET A C 1 ATOM 3911 O O . MET A 1 499 ? 63.334 71.773 -10.590 1.00 8.87 ? 499 MET A O 1 ATOM 3912 C CB . MET A 1 499 ? 61.819 73.535 -8.189 1.00 9.92 ? 499 MET A CB 1 ATOM 3913 C CG . MET A 1 499 ? 63.223 73.347 -7.668 1.00 14.56 ? 499 MET A CG 1 ATOM 3914 S SD . MET A 1 499 ? 64.517 74.386 -8.507 1.00 17.70 ? 499 MET A SD 1 ATOM 3915 C CE . MET A 1 499 ? 64.199 75.930 -7.843 1.00 12.52 ? 499 MET A CE 1 ATOM 3916 N N . VAL A 1 500 ? 61.652 70.743 -9.513 1.00 9.29 ? 500 VAL A N 1 ATOM 3917 C CA . VAL A 1 500 ? 62.194 69.403 -9.744 1.00 8.48 ? 500 VAL A CA 1 ATOM 3918 C C . VAL A 1 500 ? 62.208 69.054 -11.224 1.00 8.69 ? 500 VAL A C 1 ATOM 3919 O O . VAL A 1 500 ? 63.192 68.531 -11.762 1.00 8.61 ? 500 VAL A O 1 ATOM 3920 C CB . VAL A 1 500 ? 61.371 68.329 -8.946 1.00 7.89 ? 500 VAL A CB 1 ATOM 3921 C CG1 . VAL A 1 500 ? 61.805 66.934 -9.347 1.00 6.50 ? 500 VAL A CG1 1 ATOM 3922 C CG2 . VAL A 1 500 ? 61.618 68.509 -7.425 1.00 6.22 ? 500 VAL A CG2 1 ATOM 3923 N N . MET A 1 501 ? 61.104 69.342 -11.897 1.00 8.46 ? 501 MET A N 1 ATOM 3924 C CA . MET A 1 501 ? 61.002 69.041 -13.318 1.00 9.31 ? 501 MET A CA 1 ATOM 3925 C C . MET A 1 501 ? 62.075 69.780 -14.127 1.00 9.57 ? 501 MET A C 1 ATOM 3926 O O . MET A 1 501 ? 62.779 69.162 -14.931 1.00 10.76 ? 501 MET A O 1 ATOM 3927 C CB . MET A 1 501 ? 59.623 69.423 -13.843 1.00 8.48 ? 501 MET A CB 1 ATOM 3928 C CG . MET A 1 501 ? 58.500 68.525 -13.357 1.00 10.18 ? 501 MET A CG 1 ATOM 3929 S SD . MET A 1 501 ? 56.864 69.214 -13.633 1.00 15.39 ? 501 MET A SD 1 ATOM 3930 C CE . MET A 1 501 ? 56.716 68.972 -15.364 1.00 13.67 ? 501 MET A CE 1 ATOM 3931 N N . GLN A 1 502 ? 62.219 71.086 -13.914 1.00 8.96 ? 502 GLN A N 1 ATOM 3932 C CA . GLN A 1 502 ? 63.202 71.837 -14.697 1.00 10.17 ? 502 GLN A CA 1 ATOM 3933 C C . GLN A 1 502 ? 64.661 71.427 -14.384 1.00 10.06 ? 502 GLN A C 1 ATOM 3934 O O . GLN A 1 502 ? 65.491 71.360 -15.292 1.00 9.66 ? 502 GLN A O 1 ATOM 3935 C CB . GLN A 1 502 ? 62.969 73.354 -14.557 1.00 10.11 ? 502 GLN A CB 1 ATOM 3936 C CG . GLN A 1 502 ? 63.179 73.960 -13.158 1.00 10.98 ? 502 GLN A CG 1 ATOM 3937 C CD . GLN A 1 502 ? 64.608 74.483 -12.974 1.00 13.94 ? 502 GLN A CD 1 ATOM 3938 O OE1 . GLN A 1 502 ? 65.341 74.648 -13.968 1.00 12.17 ? 502 GLN A OE1 1 ATOM 3939 N NE2 . GLN A 1 502 ? 65.005 74.756 -11.709 1.00 12.26 ? 502 GLN A NE2 1 ATOM 3940 N N . GLN A 1 503 ? 64.969 71.119 -13.127 1.00 9.09 ? 503 GLN A N 1 ATOM 3941 C CA . GLN A 1 503 ? 66.327 70.651 -12.796 1.00 9.85 ? 503 GLN A CA 1 ATOM 3942 C C . GLN A 1 503 ? 66.540 69.320 -13.525 1.00 9.82 ? 503 GLN A C 1 ATOM 3943 O O . GLN A 1 503 ? 67.628 69.043 -14.052 1.00 9.04 ? 503 GLN A O 1 ATOM 3944 C CB . GLN A 1 503 ? 66.484 70.411 -11.285 1.00 10.55 ? 503 GLN A CB 1 ATOM 3945 C CG . GLN A 1 503 ? 66.650 71.687 -10.447 1.00 13.30 ? 503 GLN A CG 1 ATOM 3946 C CD . GLN A 1 503 ? 68.007 72.356 -10.671 1.00 15.21 ? 503 GLN A CD 1 ATOM 3947 O OE1 . GLN A 1 503 ? 68.989 71.682 -11.034 1.00 15.32 ? 503 GLN A OE1 1 ATOM 3948 N NE2 . GLN A 1 503 ? 68.074 73.684 -10.450 1.00 15.95 ? 503 GLN A NE2 1 ATOM 3949 N N . SER A 1 504 ? 65.499 68.486 -13.548 1.00 8.31 ? 504 SER A N 1 ATOM 3950 C CA . SER A 1 504 ? 65.588 67.191 -14.215 1.00 9.36 ? 504 SER A CA 1 ATOM 3951 C C . SER A 1 504 ? 65.821 67.338 -15.716 1.00 9.73 ? 504 SER A C 1 ATOM 3952 O O . SER A 1 504 ? 66.662 66.650 -16.297 1.00 10.58 ? 504 SER A O 1 ATOM 3953 C CB . SER A 1 504 ? 64.308 66.387 -13.966 1.00 9.76 ? 504 SER A CB 1 ATOM 3954 O OG . SER A 1 504 ? 64.209 66.007 -12.589 1.00 10.88 ? 504 SER A OG 1 ATOM 3955 N N . VAL A 1 505 ? 65.077 68.234 -16.354 1.00 9.66 ? 505 VAL A N 1 ATOM 3956 C CA . VAL A 1 505 ? 65.249 68.435 -17.794 1.00 10.03 ? 505 VAL A CA 1 ATOM 3957 C C . VAL A 1 505 ? 66.676 68.927 -18.079 1.00 10.94 ? 505 VAL A C 1 ATOM 3958 O O . VAL A 1 505 ? 67.357 68.477 -19.007 1.00 11.37 ? 505 VAL A O 1 ATOM 3959 C CB . VAL A 1 505 ? 64.233 69.469 -18.332 1.00 10.36 ? 505 VAL A CB 1 ATOM 3960 C CG1 . VAL A 1 505 ? 64.564 69.860 -19.797 1.00 8.91 ? 505 VAL A CG1 1 ATOM 3961 C CG2 . VAL A 1 505 ? 62.816 68.868 -18.272 1.00 10.58 ? 505 VAL A CG2 1 ATOM 3962 N N . TYR A 1 506 ? 67.133 69.860 -17.277 1.00 11.00 ? 506 TYR A N 1 ATOM 3963 C CA . TYR A 1 506 ? 68.472 70.383 -17.501 1.00 12.90 ? 506 TYR A CA 1 ATOM 3964 C C . TYR A 1 506 ? 69.526 69.258 -17.481 1.00 13.66 ? 506 TYR A C 1 ATOM 3965 O O . TYR A 1 506 ? 70.394 69.171 -18.363 1.00 12.84 ? 506 TYR A O 1 ATOM 3966 C CB . TYR A 1 506 ? 68.797 71.459 -16.453 1.00 12.71 ? 506 TYR A CB 1 ATOM 3967 C CG . TYR A 1 506 ? 70.115 72.108 -16.735 1.00 15.36 ? 506 TYR A CG 1 ATOM 3968 C CD1 . TYR A 1 506 ? 70.349 72.719 -17.976 1.00 17.55 ? 506 TYR A CD1 1 ATOM 3969 C CD2 . TYR A 1 506 ? 71.148 72.086 -15.796 1.00 16.08 ? 506 TYR A CD2 1 ATOM 3970 C CE1 . TYR A 1 506 ? 71.595 73.302 -18.276 1.00 19.78 ? 506 TYR A CE1 1 ATOM 3971 C CE2 . TYR A 1 506 ? 72.384 72.654 -16.092 1.00 19.03 ? 506 TYR A CE2 1 ATOM 3972 C CZ . TYR A 1 506 ? 72.594 73.260 -17.331 1.00 20.28 ? 506 TYR A CZ 1 ATOM 3973 O OH . TYR A 1 506 ? 73.817 73.840 -17.632 1.00 26.73 ? 506 TYR A OH 1 ATOM 3974 N N . ARG A 1 507 ? 69.436 68.386 -16.492 1.00 11.88 ? 507 ARG A N 1 ATOM 3975 C CA . ARG A 1 507 ? 70.382 67.284 -16.381 1.00 11.60 ? 507 ARG A CA 1 ATOM 3976 C C . ARG A 1 507 ? 70.246 66.233 -17.493 1.00 11.87 ? 507 ARG A C 1 ATOM 3977 O O . ARG A 1 507 ? 71.237 65.715 -18.006 1.00 10.25 ? 507 ARG A O 1 ATOM 3978 C CB . ARG A 1 507 ? 70.224 66.614 -15.018 1.00 12.13 ? 507 ARG A CB 1 ATOM 3979 C CG . ARG A 1 507 ? 71.318 65.569 -14.715 1.00 13.30 ? 507 ARG A CG 1 ATOM 3980 C CD . ARG A 1 507 ? 71.153 65.105 -13.282 1.00 13.97 ? 507 ARG A CD 1 ATOM 3981 N NE . ARG A 1 507 ? 72.188 64.161 -12.868 1.00 16.10 ? 507 ARG A NE 1 ATOM 3982 C CZ . ARG A 1 507 ? 72.243 63.596 -11.660 1.00 17.21 ? 507 ARG A CZ 1 ATOM 3983 N NH1 . ARG A 1 507 ? 71.324 63.876 -10.734 1.00 15.00 ? 507 ARG A NH1 1 ATOM 3984 N NH2 . ARG A 1 507 ? 73.211 62.734 -11.383 1.00 16.63 ? 507 ARG A NH2 1 ATOM 3985 N N . LEU A 1 508 ? 69.013 65.942 -17.868 1.00 10.35 ? 508 LEU A N 1 ATOM 3986 C CA . LEU A 1 508 ? 68.751 64.960 -18.880 1.00 10.75 ? 508 LEU A CA 1 ATOM 3987 C C . LEU A 1 508 ? 69.179 65.396 -20.262 1.00 11.56 ? 508 LEU A C 1 ATOM 3988 O O . LEU A 1 508 ? 69.531 64.567 -21.090 1.00 11.58 ? 508 LEU A O 1 ATOM 3989 C CB . LEU A 1 508 ? 67.260 64.611 -18.895 1.00 10.00 ? 508 LEU A CB 1 ATOM 3990 C CG . LEU A 1 508 ? 66.778 63.725 -17.713 1.00 11.55 ? 508 LEU A CG 1 ATOM 3991 C CD1 . LEU A 1 508 ? 65.243 63.778 -17.589 1.00 9.45 ? 508 LEU A CD1 1 ATOM 3992 C CD2 . LEU A 1 508 ? 67.260 62.280 -17.928 1.00 11.06 ? 508 LEU A CD2 1 ATOM 3993 N N . LEU A 1 509 ? 69.147 66.690 -20.536 1.00 12.23 ? 509 LEU A N 1 ATOM 3994 C CA . LEU A 1 509 ? 69.475 67.134 -21.883 1.00 11.71 ? 509 LEU A CA 1 ATOM 3995 C C . LEU A 1 509 ? 70.769 67.942 -22.021 1.00 12.70 ? 509 LEU A C 1 ATOM 3996 O O . LEU A 1 509 ? 70.925 68.705 -22.997 1.00 13.17 ? 509 LEU A O 1 ATOM 3997 C CB . LEU A 1 509 ? 68.286 67.938 -22.441 1.00 10.82 ? 509 LEU A CB 1 ATOM 3998 C CG . LEU A 1 509 ? 66.999 67.138 -22.659 1.00 11.01 ? 509 LEU A CG 1 ATOM 3999 C CD1 . LEU A 1 509 ? 65.876 68.053 -23.152 1.00 8.31 ? 509 LEU A CD1 1 ATOM 4000 C CD2 . LEU A 1 509 ? 67.245 66.010 -23.667 1.00 10.49 ? 509 LEU A CD2 1 ATOM 4001 N N . THR A 1 510 ? 71.692 67.800 -21.057 1.00 12.01 ? 510 THR A N 1 ATOM 4002 C CA . THR A 1 510 ? 72.952 68.546 -21.130 1.00 12.00 ? 510 THR A CA 1 ATOM 4003 C C . THR A 1 510 ? 74.125 67.564 -21.122 1.00 12.97 ? 510 THR A C 1 ATOM 4004 O O . THR A 1 510 ? 74.155 66.632 -20.302 1.00 11.11 ? 510 THR A O 1 ATOM 4005 C CB . THR A 1 510 ? 73.092 69.514 -19.932 1.00 12.16 ? 510 THR A CB 1 ATOM 4006 O OG1 . THR A 1 510 ? 71.993 70.440 -19.936 1.00 11.43 ? 510 THR A OG1 1 ATOM 4007 C CG2 . THR A 1 510 ? 74.391 70.295 -20.007 1.00 12.75 ? 510 THR A CG2 1 ATOM 4008 N N . LYS A 1 511 ? 75.070 67.762 -22.043 1.00 14.61 ? 511 LYS A N 1 ATOM 4009 C CA . LYS A 1 511 ? 76.276 66.908 -22.140 1.00 15.77 ? 511 LYS A CA 1 ATOM 4010 C C . LYS A 1 511 ? 76.769 66.744 -20.730 1.00 15.37 ? 511 LYS A C 1 ATOM 4011 O O . LYS A 1 511 ? 76.993 67.722 -20.035 1.00 17.07 ? 511 LYS A O 1 ATOM 4012 C CB . LYS A 1 511 ? 77.366 67.563 -23.029 1.00 17.19 ? 511 LYS A CB 1 ATOM 4013 C CG . LYS A 1 511 ? 78.516 66.608 -23.263 1.00 20.45 ? 511 LYS A CG 1 ATOM 4014 C CD . LYS A 1 511 ? 79.665 67.127 -24.099 1.00 22.73 ? 511 LYS A CD 1 ATOM 4015 C CE . LYS A 1 511 ? 80.797 66.068 -24.009 1.00 24.97 ? 511 LYS A CE 1 ATOM 4016 N NZ . LYS A 1 511 ? 81.981 66.240 -24.908 1.00 28.46 ? 511 LYS A NZ 1 ATOM 4017 N N . PRO A 1 512 ? 76.937 65.495 -20.270 1.00 16.71 ? 512 PRO A N 1 ATOM 4018 C CA . PRO A 1 512 ? 77.393 65.240 -18.898 1.00 16.72 ? 512 PRO A CA 1 ATOM 4019 C C . PRO A 1 512 ? 78.614 66.019 -18.389 1.00 17.15 ? 512 PRO A C 1 ATOM 4020 O O . PRO A 1 512 ? 78.598 66.551 -17.267 1.00 17.40 ? 512 PRO A O 1 ATOM 4021 C CB . PRO A 1 512 ? 77.602 63.724 -18.882 1.00 17.28 ? 512 PRO A CB 1 ATOM 4022 C CG . PRO A 1 512 ? 76.548 63.234 -19.889 1.00 18.35 ? 512 PRO A CG 1 ATOM 4023 C CD . PRO A 1 512 ? 76.688 64.235 -21.003 1.00 17.52 ? 512 PRO A CD 1 ATOM 4024 N N . SER A 1 513 ? 79.660 66.105 -19.209 1.00 16.64 ? 513 SER A N 1 ATOM 4025 C CA . SER A 1 513 ? 80.872 66.795 -18.788 1.00 16.38 ? 513 SER A CA 1 ATOM 4026 C C . SER A 1 513 ? 80.765 68.303 -18.778 1.00 16.86 ? 513 SER A C 1 ATOM 4027 O O . SER A 1 513 ? 81.708 68.986 -18.417 1.00 16.22 ? 513 SER A O 1 ATOM 4028 C CB . SER A 1 513 ? 82.058 66.366 -19.665 1.00 15.99 ? 513 SER A CB 1 ATOM 4029 O OG . SER A 1 513 ? 81.821 66.626 -21.034 1.00 16.61 ? 513 SER A OG 1 ATOM 4030 N N . ILE A 1 514 ? 79.615 68.818 -19.177 1.00 17.17 ? 514 ILE A N 1 ATOM 4031 C CA . ILE A 1 514 ? 79.367 70.252 -19.220 1.00 18.40 ? 514 ILE A CA 1 ATOM 4032 C C . ILE A 1 514 ? 78.359 70.606 -18.109 1.00 18.77 ? 514 ILE A C 1 ATOM 4033 O O . ILE A 1 514 ? 78.380 71.701 -17.552 1.00 18.80 ? 514 ILE A O 1 ATOM 4034 C CB . ILE A 1 514 ? 78.806 70.646 -20.631 1.00 18.90 ? 514 ILE A CB 1 ATOM 4035 C CG1 . ILE A 1 514 ? 79.909 70.493 -21.675 1.00 19.34 ? 514 ILE A CG1 1 ATOM 4036 C CG2 . ILE A 1 514 ? 78.323 72.082 -20.650 1.00 20.98 ? 514 ILE A CG2 1 ATOM 4037 C CD1 . ILE A 1 514 ? 79.460 70.722 -23.112 1.00 20.07 ? 514 ILE A CD1 1 ATOM 4038 N N . TYR A 1 515 ? 77.472 69.666 -17.794 1.00 18.95 ? 515 TYR A N 1 ATOM 4039 C CA . TYR A 1 515 ? 76.455 69.856 -16.760 1.00 17.70 ? 515 TYR A CA 1 ATOM 4040 C C . TYR A 1 515 ? 77.037 70.385 -15.429 1.00 18.04 ? 515 TYR A C 1 ATOM 4041 O O . TYR A 1 515 ? 77.818 69.705 -14.758 1.00 17.94 ? 515 TYR A O 1 ATOM 4042 C CB . TYR A 1 515 ? 75.753 68.519 -16.558 1.00 16.92 ? 515 TYR A CB 1 ATOM 4043 C CG . TYR A 1 515 ? 74.751 68.507 -15.462 1.00 16.39 ? 515 TYR A CG 1 ATOM 4044 C CD1 . TYR A 1 515 ? 73.601 69.293 -15.526 1.00 15.86 ? 515 TYR A CD1 1 ATOM 4045 C CD2 . TYR A 1 515 ? 74.924 67.676 -14.360 1.00 15.68 ? 515 TYR A CD2 1 ATOM 4046 C CE1 . TYR A 1 515 ? 72.639 69.243 -14.505 1.00 15.88 ? 515 TYR A CE1 1 ATOM 4047 C CE2 . TYR A 1 515 ? 73.966 67.613 -13.338 1.00 15.70 ? 515 TYR A CE2 1 ATOM 4048 C CZ . TYR A 1 515 ? 72.822 68.402 -13.419 1.00 16.55 ? 515 TYR A CZ 1 ATOM 4049 O OH . TYR A 1 515 ? 71.870 68.342 -12.402 1.00 16.32 ? 515 TYR A OH 1 ATOM 4050 N N . SER A 1 516 ? 76.646 71.595 -15.037 1.00 17.32 ? 516 SER A N 1 ATOM 4051 C CA . SER A 1 516 ? 77.168 72.233 -13.810 1.00 17.13 ? 516 SER A CA 1 ATOM 4052 C C . SER A 1 516 ? 75.988 72.873 -13.110 1.00 17.26 ? 516 SER A C 1 ATOM 4053 O O . SER A 1 516 ? 75.775 74.093 -13.203 1.00 17.03 ? 516 SER A O 1 ATOM 4054 C CB . SER A 1 516 ? 78.186 73.316 -14.200 1.00 16.91 ? 516 SER A CB 1 ATOM 4055 O OG . SER A 1 516 ? 78.811 73.858 -13.046 1.00 18.28 ? 516 SER A OG 1 ATOM 4056 N N . PRO A 1 517 ? 75.217 72.072 -12.366 1.00 17.54 ? 517 PRO A N 1 ATOM 4057 C CA . PRO A 1 517 ? 74.042 72.607 -11.697 1.00 17.38 ? 517 PRO A CA 1 ATOM 4058 C C . PRO A 1 517 ? 74.114 73.461 -10.444 1.00 18.14 ? 517 PRO A C 1 ATOM 4059 O O . PRO A 1 517 ? 74.937 73.245 -9.562 1.00 18.88 ? 517 PRO A O 1 ATOM 4060 C CB . PRO A 1 517 ? 73.201 71.350 -11.472 1.00 18.05 ? 517 PRO A CB 1 ATOM 4061 C CG . PRO A 1 517 ? 74.247 70.355 -11.072 1.00 17.70 ? 517 PRO A CG 1 ATOM 4062 C CD . PRO A 1 517 ? 75.330 70.621 -12.145 1.00 17.60 ? 517 PRO A CD 1 ATOM 4063 N N . ASP A 1 518 ? 73.238 74.457 -10.422 1.00 19.01 ? 518 ASP A N 1 ATOM 4064 C CA . ASP A 1 518 ? 73.010 75.324 -9.270 1.00 18.93 ? 518 ASP A CA 1 ATOM 4065 C C . ASP A 1 518 ? 71.586 74.861 -8.915 1.00 18.65 ? 518 ASP A C 1 ATOM 4066 O O . ASP A 1 518 ? 70.606 75.186 -9.609 1.00 18.75 ? 518 ASP A O 1 ATOM 4067 C CB . ASP A 1 518 ? 72.979 76.802 -9.647 1.00 20.11 ? 518 ASP A CB 1 ATOM 4068 C CG . ASP A 1 518 ? 72.571 77.670 -8.479 1.00 21.83 ? 518 ASP A CG 1 ATOM 4069 O OD1 . ASP A 1 518 ? 71.934 77.137 -7.543 1.00 22.53 ? 518 ASP A OD1 1 ATOM 4070 O OD2 . ASP A 1 518 ? 72.865 78.878 -8.492 1.00 24.19 ? 518 ASP A OD2 1 ATOM 4071 N N . PHE A 1 519 ? 71.479 74.083 -7.851 1.00 17.90 ? 519 PHE A N 1 ATOM 4072 C CA . PHE A 1 519 ? 70.202 73.524 -7.459 1.00 17.88 ? 519 PHE A CA 1 ATOM 4073 C C . PHE A 1 519 ? 69.131 74.526 -7.082 1.00 18.28 ? 519 PHE A C 1 ATOM 4074 O O . PHE A 1 519 ? 67.977 74.154 -6.908 1.00 18.28 ? 519 PHE A O 1 ATOM 4075 C CB . PHE A 1 519 ? 70.417 72.492 -6.338 1.00 17.49 ? 519 PHE A CB 1 ATOM 4076 C CG . PHE A 1 519 ? 71.261 71.311 -6.768 1.00 17.26 ? 519 PHE A CG 1 ATOM 4077 C CD1 . PHE A 1 519 ? 70.982 70.645 -7.958 1.00 17.26 ? 519 PHE A CD1 1 ATOM 4078 C CD2 . PHE A 1 519 ? 72.350 70.899 -6.009 1.00 18.19 ? 519 PHE A CD2 1 ATOM 4079 C CE1 . PHE A 1 519 ? 71.766 69.605 -8.390 1.00 17.33 ? 519 PHE A CE1 1 ATOM 4080 C CE2 . PHE A 1 519 ? 73.152 69.856 -6.422 1.00 17.13 ? 519 PHE A CE2 1 ATOM 4081 C CZ . PHE A 1 519 ? 72.867 69.202 -7.617 1.00 19.37 ? 519 PHE A CZ 1 ATOM 4082 N N . SER A 1 520 ? 69.480 75.802 -6.994 1.00 18.52 ? 520 SER A N 1 ATOM 4083 C CA . SER A 1 520 ? 68.474 76.803 -6.642 1.00 19.41 ? 520 SER A CA 1 ATOM 4084 C C . SER A 1 520 ? 68.139 77.650 -7.870 1.00 19.22 ? 520 SER A C 1 ATOM 4085 O O . SER A 1 520 ? 67.288 78.534 -7.810 1.00 18.88 ? 520 SER A O 1 ATOM 4086 C CB . SER A 1 520 ? 69.011 77.740 -5.555 1.00 19.03 ? 520 SER A CB 1 ATOM 4087 O OG . SER A 1 520 ? 70.037 78.562 -6.108 1.00 19.65 ? 520 SER A OG 1 ATOM 4088 N N . PHE A 1 521 ? 68.806 77.376 -8.983 1.00 19.49 ? 521 PHE A N 1 ATOM 4089 C CA . PHE A 1 521 ? 68.608 78.161 -10.203 1.00 19.23 ? 521 PHE A CA 1 ATOM 4090 C C . PHE A 1 521 ? 67.480 77.634 -11.095 1.00 19.22 ? 521 PHE A C 1 ATOM 4091 O O . PHE A 1 521 ? 67.174 76.448 -11.075 1.00 19.40 ? 521 PHE A O 1 ATOM 4092 C CB . PHE A 1 521 ? 69.934 78.209 -10.989 1.00 20.25 ? 521 PHE A CB 1 ATOM 4093 C CG . PHE A 1 521 ? 69.933 79.197 -12.123 1.00 22.21 ? 521 PHE A CG 1 ATOM 4094 C CD1 . PHE A 1 521 ? 69.978 80.569 -11.868 1.00 23.29 ? 521 PHE A CD1 1 ATOM 4095 C CD2 . PHE A 1 521 ? 69.789 78.759 -13.444 1.00 22.39 ? 521 PHE A CD2 1 ATOM 4096 C CE1 . PHE A 1 521 ? 69.869 81.495 -12.910 1.00 24.08 ? 521 PHE A CE1 1 ATOM 4097 C CE2 . PHE A 1 521 ? 69.679 79.671 -14.498 1.00 23.71 ? 521 PHE A CE2 1 ATOM 4098 C CZ . PHE A 1 521 ? 69.716 81.044 -14.233 1.00 24.32 ? 521 PHE A CZ 1 ATOM 4099 N N . SER A 1 522 ? 66.851 78.525 -11.864 1.00 18.76 ? 522 SER A N 1 ATOM 4100 C CA . SER A 1 522 ? 65.778 78.114 -12.764 1.00 19.01 ? 522 SER A CA 1 ATOM 4101 C C . SER A 1 522 ? 66.285 78.070 -14.198 1.00 16.92 ? 522 SER A C 1 ATOM 4102 O O . SER A 1 522 ? 66.315 79.095 -14.871 1.00 17.17 ? 522 SER A O 1 ATOM 4103 C CB . SER A 1 522 ? 64.577 79.081 -12.688 1.00 20.10 ? 522 SER A CB 1 ATOM 4104 O OG . SER A 1 522 ? 63.811 78.846 -11.524 1.00 26.11 ? 522 SER A OG 1 ATOM 4105 N N . TYR A 1 523 ? 66.676 76.894 -14.660 1.00 15.32 ? 523 TYR A N 1 ATOM 4106 C CA . TYR A 1 523 ? 67.153 76.729 -16.031 1.00 14.19 ? 523 TYR A CA 1 ATOM 4107 C C . TYR A 1 523 ? 66.021 76.827 -17.042 1.00 14.30 ? 523 TYR A C 1 ATOM 4108 O O . TYR A 1 523 ? 66.227 77.231 -18.186 1.00 14.16 ? 523 TYR A O 1 ATOM 4109 C CB . TYR A 1 523 ? 67.857 75.370 -16.182 1.00 13.64 ? 523 TYR A CB 1 ATOM 4110 C CG . TYR A 1 523 ? 69.141 75.331 -15.373 1.00 14.97 ? 523 TYR A CG 1 ATOM 4111 C CD1 . TYR A 1 523 ? 69.174 74.761 -14.102 1.00 13.89 ? 523 TYR A CD1 1 ATOM 4112 C CD2 . TYR A 1 523 ? 70.311 75.951 -15.863 1.00 15.08 ? 523 TYR A CD2 1 ATOM 4113 C CE1 . TYR A 1 523 ? 70.335 74.818 -13.334 1.00 14.92 ? 523 TYR A CE1 1 ATOM 4114 C CE2 . TYR A 1 523 ? 71.473 76.009 -15.109 1.00 14.68 ? 523 TYR A CE2 1 ATOM 4115 C CZ . TYR A 1 523 ? 71.485 75.454 -13.854 1.00 14.58 ? 523 TYR A CZ 1 ATOM 4116 O OH . TYR A 1 523 ? 72.624 75.561 -13.089 1.00 16.65 ? 523 TYR A OH 1 ATOM 4117 N N . PHE A 1 524 ? 64.829 76.409 -16.627 1.00 13.34 ? 524 PHE A N 1 ATOM 4118 C CA . PHE A 1 524 ? 63.654 76.478 -17.496 1.00 12.75 ? 524 PHE A CA 1 ATOM 4119 C C . PHE A 1 524 ? 62.464 76.961 -16.694 1.00 13.79 ? 524 PHE A C 1 ATOM 4120 O O . PHE A 1 524 ? 62.422 76.784 -15.472 1.00 13.39 ? 524 PHE A O 1 ATOM 4121 C CB . PHE A 1 524 ? 63.253 75.101 -18.035 1.00 12.26 ? 524 PHE A CB 1 ATOM 4122 C CG . PHE A 1 524 ? 64.283 74.454 -18.901 1.00 12.61 ? 524 PHE A CG 1 ATOM 4123 C CD1 . PHE A 1 524 ? 65.331 73.729 -18.336 1.00 12.07 ? 524 PHE A CD1 1 ATOM 4124 C CD2 . PHE A 1 524 ? 64.209 74.562 -20.290 1.00 11.08 ? 524 PHE A CD2 1 ATOM 4125 C CE1 . PHE A 1 524 ? 66.300 73.113 -19.168 1.00 12.42 ? 524 PHE A CE1 1 ATOM 4126 C CE2 . PHE A 1 524 ? 65.155 73.961 -21.114 1.00 11.74 ? 524 PHE A CE2 1 ATOM 4127 C CZ . PHE A 1 524 ? 66.205 73.232 -20.553 1.00 12.70 ? 524 PHE A CZ 1 ATOM 4128 N N . THR A 1 525 ? 61.502 77.571 -17.369 1.00 14.00 ? 525 THR A N 1 ATOM 4129 C CA . THR A 1 525 ? 60.274 77.924 -16.697 1.00 16.42 ? 525 THR A CA 1 ATOM 4130 C C . THR A 1 525 ? 59.221 77.113 -17.445 1.00 16.11 ? 525 THR A C 1 ATOM 4131 O O . THR A 1 525 ? 59.281 76.958 -18.669 1.00 15.28 ? 525 THR A O 1 ATOM 4132 C CB . THR A 1 525 ? 59.944 79.399 -16.814 1.00 17.11 ? 525 THR A CB 1 ATOM 4133 O OG1 . THR A 1 525 ? 59.637 79.685 -18.169 1.00 21.56 ? 525 THR A OG1 1 ATOM 4134 C CG2 . THR A 1 525 ? 61.129 80.242 -16.378 1.00 18.93 ? 525 THR A CG2 1 ATOM 4135 N N . LEU A 1 526 ? 58.265 76.577 -16.704 1.00 15.82 ? 526 LEU A N 1 ATOM 4136 C CA . LEU A 1 526 ? 57.215 75.763 -17.295 1.00 16.66 ? 526 LEU A CA 1 ATOM 4137 C C . LEU A 1 526 ? 56.195 76.695 -17.998 1.00 16.27 ? 526 LEU A C 1 ATOM 4138 O O . LEU A 1 526 ? 55.929 77.797 -17.517 1.00 15.58 ? 526 LEU A O 1 ATOM 4139 C CB . LEU A 1 526 ? 56.550 74.971 -16.162 1.00 18.79 ? 526 LEU A CB 1 ATOM 4140 C CG . LEU A 1 526 ? 56.255 73.468 -16.185 1.00 24.12 ? 526 LEU A CG 1 ATOM 4141 C CD1 . LEU A 1 526 ? 57.160 72.725 -17.104 1.00 22.91 ? 526 LEU A CD1 1 ATOM 4142 C CD2 . LEU A 1 526 ? 56.402 72.938 -14.773 1.00 24.78 ? 526 LEU A CD2 1 ATOM 4143 N N . ASP A 1 527 ? 55.664 76.283 -19.145 1.00 13.85 ? 527 ASP A N 1 ATOM 4144 C CA . ASP A 1 527 ? 54.658 77.100 -19.824 1.00 15.17 ? 527 ASP A CA 1 ATOM 4145 C C . ASP A 1 527 ? 53.434 76.208 -19.907 1.00 15.04 ? 527 ASP A C 1 ATOM 4146 O O . ASP A 1 527 ? 53.490 75.149 -20.519 1.00 16.07 ? 527 ASP A O 1 ATOM 4147 C CB . ASP A 1 527 ? 55.126 77.508 -21.225 1.00 15.22 ? 527 ASP A CB 1 ATOM 4148 C CG . ASP A 1 527 ? 54.087 78.363 -21.970 1.00 17.48 ? 527 ASP A CG 1 ATOM 4149 O OD1 . ASP A 1 527 ? 53.790 79.481 -21.504 1.00 15.37 ? 527 ASP A OD1 1 ATOM 4150 O OD2 . ASP A 1 527 ? 53.564 77.906 -23.020 1.00 15.85 ? 527 ASP A OD2 1 ATOM 4151 N N . ASP A 1 528 ? 52.349 76.613 -19.251 1.00 14.23 ? 528 ASP A N 1 ATOM 4152 C CA . ASP A 1 528 ? 51.111 75.828 -19.231 1.00 12.47 ? 528 ASP A CA 1 ATOM 4153 C C . ASP A 1 528 ? 50.016 76.686 -19.834 1.00 12.51 ? 528 ASP A C 1 ATOM 4154 O O . ASP A 1 528 ? 49.654 77.718 -19.273 1.00 11.20 ? 528 ASP A O 1 ATOM 4155 C CB . ASP A 1 528 ? 50.750 75.438 -17.784 1.00 12.60 ? 528 ASP A CB 1 ATOM 4156 C CG . ASP A 1 528 ? 49.665 74.353 -17.710 1.00 12.97 ? 528 ASP A CG 1 ATOM 4157 O OD1 . ASP A 1 528 ? 48.646 74.434 -18.421 1.00 11.19 ? 528 ASP A OD1 1 ATOM 4158 O OD2 . ASP A 1 528 ? 49.836 73.406 -16.928 1.00 12.17 ? 528 ASP A OD2 1 ATOM 4159 N N . SER A 1 529 ? 49.487 76.250 -20.975 1.00 11.73 ? 529 SER A N 1 ATOM 4160 C CA . SER A 1 529 ? 48.439 77.006 -21.682 1.00 13.98 ? 529 SER A CA 1 ATOM 4161 C C . SER A 1 529 ? 47.077 76.929 -21.032 1.00 14.36 ? 529 SER A C 1 ATOM 4162 O O . SER A 1 529 ? 46.221 77.752 -21.323 1.00 13.99 ? 529 SER A O 1 ATOM 4163 C CB . SER A 1 529 ? 48.230 76.481 -23.109 1.00 13.49 ? 529 SER A CB 1 ATOM 4164 O OG . SER A 1 529 ? 49.432 76.492 -23.831 1.00 16.92 ? 529 SER A OG 1 ATOM 4165 N N . ARG A 1 530 ? 46.858 75.922 -20.184 1.00 13.67 ? 530 ARG A N 1 ATOM 4166 C CA . ARG A 1 530 ? 45.526 75.766 -19.630 1.00 14.39 ? 530 ARG A CA 1 ATOM 4167 C C . ARG A 1 530 ? 45.362 75.951 -18.132 1.00 15.75 ? 530 ARG A C 1 ATOM 4168 O O . ARG A 1 530 ? 44.263 75.761 -17.601 1.00 16.70 ? 530 ARG A O 1 ATOM 4169 C CB . ARG A 1 530 ? 44.972 74.420 -20.100 1.00 12.08 ? 530 ARG A CB 1 ATOM 4170 C CG . ARG A 1 530 ? 44.933 74.363 -21.617 1.00 13.03 ? 530 ARG A CG 1 ATOM 4171 C CD . ARG A 1 530 ? 44.263 73.099 -22.179 1.00 14.04 ? 530 ARG A CD 1 ATOM 4172 N NE . ARG A 1 530 ? 45.023 71.897 -21.826 1.00 12.31 ? 530 ARG A NE 1 ATOM 4173 C CZ . ARG A 1 530 ? 44.853 70.718 -22.410 1.00 14.52 ? 530 ARG A CZ 1 ATOM 4174 N NH1 . ARG A 1 530 ? 43.949 70.585 -23.390 1.00 13.13 ? 530 ARG A NH1 1 ATOM 4175 N NH2 . ARG A 1 530 ? 45.544 69.657 -21.988 1.00 11.79 ? 530 ARG A NH2 1 ATOM 4176 N N . TRP A 1 531 ? 46.435 76.323 -17.442 1.00 14.25 ? 531 TRP A N 1 ATOM 4177 C CA . TRP A 1 531 ? 46.308 76.573 -16.006 1.00 14.94 ? 531 TRP A CA 1 ATOM 4178 C C . TRP A 1 531 ? 47.300 77.635 -15.556 1.00 14.97 ? 531 TRP A C 1 ATOM 4179 O O . TRP A 1 531 ? 48.493 77.489 -15.782 1.00 16.05 ? 531 TRP A O 1 ATOM 4180 C CB . TRP A 1 531 ? 46.529 75.303 -15.178 1.00 13.48 ? 531 TRP A CB 1 ATOM 4181 C CG . TRP A 1 531 ? 46.407 75.612 -13.726 1.00 15.33 ? 531 TRP A CG 1 ATOM 4182 C CD1 . TRP A 1 531 ? 47.414 76.013 -12.870 1.00 16.31 ? 531 TRP A CD1 1 ATOM 4183 C CD2 . TRP A 1 531 ? 45.190 75.690 -12.971 1.00 16.02 ? 531 TRP A CD2 1 ATOM 4184 N NE1 . TRP A 1 531 ? 46.885 76.336 -11.634 1.00 16.22 ? 531 TRP A NE1 1 ATOM 4185 C CE2 . TRP A 1 531 ? 45.526 76.150 -11.673 1.00 17.40 ? 531 TRP A CE2 1 ATOM 4186 C CE3 . TRP A 1 531 ? 43.856 75.422 -13.266 1.00 18.11 ? 531 TRP A CE3 1 ATOM 4187 C CZ2 . TRP A 1 531 ? 44.567 76.341 -10.679 1.00 19.15 ? 531 TRP A CZ2 1 ATOM 4188 C CZ3 . TRP A 1 531 ? 42.884 75.616 -12.265 1.00 18.62 ? 531 TRP A CZ3 1 ATOM 4189 C CH2 . TRP A 1 531 ? 43.250 76.069 -10.996 1.00 20.44 ? 531 TRP A CH2 1 ATOM 4190 N N . PRO A 1 532 ? 46.819 78.694 -14.878 1.00 15.64 ? 532 PRO A N 1 ATOM 4191 C CA . PRO A 1 532 ? 45.412 78.928 -14.514 1.00 16.11 ? 532 PRO A CA 1 ATOM 4192 C C . PRO A 1 532 ? 44.476 79.121 -15.707 1.00 16.97 ? 532 PRO A C 1 ATOM 4193 O O . PRO A 1 532 ? 43.242 78.985 -15.579 1.00 16.44 ? 532 PRO A O 1 ATOM 4194 C CB . PRO A 1 532 ? 45.484 80.172 -13.610 1.00 17.13 ? 532 PRO A CB 1 ATOM 4195 C CG . PRO A 1 532 ? 46.849 80.003 -12.937 1.00 16.83 ? 532 PRO A CG 1 ATOM 4196 C CD . PRO A 1 532 ? 47.702 79.647 -14.180 1.00 15.92 ? 532 PRO A CD 1 ATOM 4197 N N . GLY A 1 533 ? 45.081 79.390 -16.861 1.00 17.24 ? 533 GLY A N 1 ATOM 4198 C CA . GLY A 1 533 ? 44.344 79.559 -18.090 1.00 20.38 ? 533 GLY A CA 1 ATOM 4199 C C . GLY A 1 533 ? 44.192 81.007 -18.468 1.00 23.77 ? 533 GLY A C 1 ATOM 4200 O O . GLY A 1 533 ? 44.210 81.901 -17.606 1.00 23.04 ? 533 GLY A O 1 ATOM 4201 N N . SER A 1 534 ? 44.052 81.237 -19.770 1.00 27.55 ? 534 SER A N 1 ATOM 4202 C CA . SER A 1 534 ? 43.885 82.588 -20.328 1.00 30.99 ? 534 SER A CA 1 ATOM 4203 C C . SER A 1 534 ? 42.594 83.199 -19.769 1.00 31.65 ? 534 SER A C 1 ATOM 4204 O O . SER A 1 534 ? 41.525 82.582 -19.843 1.00 32.14 ? 534 SER A O 1 ATOM 4205 C CB . SER A 1 534 ? 43.832 82.501 -21.872 1.00 32.51 ? 534 SER A CB 1 ATOM 4206 O OG . SER A 1 534 ? 43.441 83.732 -22.460 1.00 36.46 ? 534 SER A OG 1 ATOM 4207 N N . GLY A 1 535 ? 42.697 84.397 -19.199 1.00 32.92 ? 535 GLY A N 1 ATOM 4208 C CA . GLY A 1 535 ? 41.526 85.039 -18.620 1.00 34.58 ? 535 GLY A CA 1 ATOM 4209 C C . GLY A 1 535 ? 41.356 84.709 -17.138 1.00 35.68 ? 535 GLY A C 1 ATOM 4210 O O . GLY A 1 535 ? 40.492 85.275 -16.452 1.00 35.86 ? 535 GLY A O 1 ATOM 4211 N N . VAL A 1 536 ? 42.166 83.780 -16.630 1.00 36.02 ? 536 VAL A N 1 ATOM 4212 C CA . VAL A 1 536 ? 42.084 83.413 -15.219 1.00 36.81 ? 536 VAL A CA 1 ATOM 4213 C C . VAL A 1 536 ? 43.258 84.103 -14.521 1.00 38.28 ? 536 VAL A C 1 ATOM 4214 O O . VAL A 1 536 ? 43.110 84.670 -13.439 1.00 37.43 ? 536 VAL A O 1 ATOM 4215 C CB . VAL A 1 536 ? 42.165 81.861 -15.021 1.00 36.60 ? 536 VAL A CB 1 ATOM 4216 C CG1 . VAL A 1 536 ? 41.822 81.484 -13.591 1.00 35.48 ? 536 VAL A CG1 1 ATOM 4217 C CG2 . VAL A 1 536 ? 41.215 81.168 -15.971 1.00 35.83 ? 536 VAL A CG2 1 ATOM 4218 N N . GLU A 1 537 ? 44.415 84.076 -15.179 1.00 39.84 ? 537 GLU A N 1 ATOM 4219 C CA . GLU A 1 537 ? 45.622 84.689 -14.650 1.00 41.85 ? 537 GLU A CA 1 ATOM 4220 C C . GLU A 1 537 ? 46.652 84.873 -15.769 1.00 42.16 ? 537 GLU A C 1 ATOM 4221 O O . GLU A 1 537 ? 46.936 83.934 -16.525 1.00 42.39 ? 537 GLU A O 1 ATOM 4222 C CB . GLU A 1 537 ? 46.172 83.807 -13.524 1.00 43.44 ? 537 GLU A CB 1 ATOM 4223 C CG . GLU A 1 537 ? 47.595 84.110 -13.084 1.00 46.64 ? 537 GLU A CG 1 ATOM 4224 C CD . GLU A 1 537 ? 47.987 83.358 -11.799 1.00 49.06 ? 537 GLU A CD 1 ATOM 4225 O OE1 . GLU A 1 537 ? 49.158 82.888 -11.712 1.00 50.01 ? 537 GLU A OE1 1 ATOM 4226 O OE2 . GLU A 1 537 ? 47.126 83.244 -10.879 1.00 49.61 ? 537 GLU A OE2 1 ATOM 4227 N N . ASP A 1 538 ? 47.198 86.083 -15.907 1.00 42.38 ? 538 ASP A N 1 ATOM 4228 C CA . ASP A 1 538 ? 48.206 86.301 -16.955 1.00 42.18 ? 538 ASP A CA 1 ATOM 4229 C C . ASP A 1 538 ? 49.521 85.849 -16.327 1.00 40.46 ? 538 ASP A C 1 ATOM 4230 O O . ASP A 1 538 ? 50.282 86.660 -15.798 1.00 40.63 ? 538 ASP A O 1 ATOM 4231 C CB . ASP A 1 538 ? 48.275 87.783 -17.365 1.00 44.18 ? 538 ASP A CB 1 ATOM 4232 C CG . ASP A 1 538 ? 48.869 87.975 -18.773 1.00 46.20 ? 538 ASP A CG 1 ATOM 4233 O OD1 . ASP A 1 538 ? 49.881 87.302 -19.077 1.00 48.04 ? 538 ASP A OD1 1 ATOM 4234 O OD2 . ASP A 1 538 ? 48.336 88.795 -19.568 1.00 46.65 ? 538 ASP A OD2 1 ATOM 4235 N N . SER A 1 539 ? 49.787 84.547 -16.385 1.00 38.36 ? 539 SER A N 1 ATOM 4236 C CA . SER A 1 539 ? 50.991 84.002 -15.747 1.00 35.87 ? 539 SER A CA 1 ATOM 4237 C C . SER A 1 539 ? 52.056 83.476 -16.690 1.00 33.82 ? 539 SER A C 1 ATOM 4238 O O . SER A 1 539 ? 53.177 83.180 -16.251 1.00 34.13 ? 539 SER A O 1 ATOM 4239 C CB . SER A 1 539 ? 50.609 82.862 -14.793 1.00 35.22 ? 539 SER A CB 1 ATOM 4240 O OG . SER A 1 539 ? 50.219 81.702 -15.526 1.00 35.67 ? 539 SER A OG 1 ATOM 4241 N N . ARG A 1 540 ? 51.706 83.334 -17.965 1.00 31.30 ? 540 ARG A N 1 ATOM 4242 C CA . ARG A 1 540 ? 52.640 82.805 -18.952 1.00 28.28 ? 540 ARG A CA 1 ATOM 4243 C C . ARG A 1 540 ? 53.676 83.824 -19.362 1.00 27.42 ? 540 ARG A C 1 ATOM 4244 O O . ARG A 1 540 ? 53.394 85.019 -19.488 1.00 26.49 ? 540 ARG A O 1 ATOM 4245 C CB . ARG A 1 540 ? 51.882 82.320 -20.172 1.00 27.36 ? 540 ARG A CB 1 ATOM 4246 C CG . ARG A 1 540 ? 50.909 81.199 -19.841 1.00 24.05 ? 540 ARG A CG 1 ATOM 4247 C CD . ARG A 1 540 ? 50.164 80.774 -21.087 1.00 22.35 ? 540 ARG A CD 1 ATOM 4248 N NE . ARG A 1 540 ? 51.059 80.163 -22.057 1.00 18.38 ? 540 ARG A NE 1 ATOM 4249 C CZ . ARG A 1 540 ? 50.683 79.827 -23.285 1.00 19.10 ? 540 ARG A CZ 1 ATOM 4250 N NH1 . ARG A 1 540 ? 49.435 80.058 -23.679 1.00 15.94 ? 540 ARG A NH1 1 ATOM 4251 N NH2 . ARG A 1 540 ? 51.549 79.252 -24.114 1.00 18.77 ? 540 ARG A NH2 1 ATOM 4252 N N . THR A 1 541 ? 54.891 83.352 -19.559 1.00 26.32 ? 541 THR A N 1 ATOM 4253 C CA . THR A 1 541 ? 55.932 84.264 -19.945 1.00 26.28 ? 541 THR A CA 1 ATOM 4254 C C . THR A 1 541 ? 56.006 84.313 -21.467 1.00 24.49 ? 541 THR A C 1 ATOM 4255 O O . THR A 1 541 ? 55.789 83.324 -22.153 1.00 24.72 ? 541 THR A O 1 ATOM 4256 C CB . THR A 1 541 ? 57.295 83.828 -19.384 1.00 28.58 ? 541 THR A CB 1 ATOM 4257 O OG1 . THR A 1 541 ? 57.887 82.888 -20.280 1.00 31.14 ? 541 THR A OG1 1 ATOM 4258 C CG2 . THR A 1 541 ? 57.136 83.168 -17.992 1.00 28.10 ? 541 THR A CG2 1 ATOM 4259 N N . THR A 1 542 ? 56.285 85.492 -21.990 1.00 22.08 ? 542 THR A N 1 ATOM 4260 C CA . THR A 1 542 ? 56.423 85.661 -23.411 1.00 19.10 ? 542 THR A CA 1 ATOM 4261 C C . THR A 1 542 ? 57.873 85.419 -23.751 1.00 17.52 ? 542 THR A C 1 ATOM 4262 O O . THR A 1 542 ? 58.752 85.912 -23.054 1.00 18.85 ? 542 THR A O 1 ATOM 4263 C CB . THR A 1 542 ? 56.064 87.087 -23.808 1.00 18.77 ? 542 THR A CB 1 ATOM 4264 O OG1 . THR A 1 542 ? 54.676 87.295 -23.556 1.00 19.36 ? 542 THR A OG1 1 ATOM 4265 C CG2 . THR A 1 542 ? 56.357 87.328 -25.276 1.00 17.31 ? 542 THR A CG2 1 ATOM 4266 N N . ILE A 1 543 ? 58.128 84.625 -24.785 1.00 15.49 ? 543 ILE A N 1 ATOM 4267 C CA . ILE A 1 543 ? 59.500 84.401 -25.237 1.00 14.21 ? 543 ILE A CA 1 ATOM 4268 C C . ILE A 1 543 ? 59.835 85.693 -26.015 1.00 14.64 ? 543 ILE A C 1 ATOM 4269 O O . ILE A 1 543 ? 59.236 85.967 -27.063 1.00 13.70 ? 543 ILE A O 1 ATOM 4270 C CB . ILE A 1 543 ? 59.589 83.197 -26.160 1.00 13.31 ? 543 ILE A CB 1 ATOM 4271 C CG1 . ILE A 1 543 ? 59.242 81.931 -25.345 1.00 12.40 ? 543 ILE A CG1 1 ATOM 4272 C CG2 . ILE A 1 543 ? 61.009 83.138 -26.819 1.00 10.85 ? 543 ILE A CG2 1 ATOM 4273 C CD1 . ILE A 1 543 ? 59.180 80.657 -26.146 1.00 11.04 ? 543 ILE A CD1 1 ATOM 4274 N N . ILE A 1 544 ? 60.768 86.475 -25.475 1.00 14.11 ? 544 ILE A N 1 ATOM 4275 C CA . ILE A 1 544 ? 61.145 87.759 -26.043 1.00 14.77 ? 544 ILE A CA 1 ATOM 4276 C C . ILE A 1 544 ? 62.356 87.629 -26.931 1.00 15.52 ? 544 ILE A C 1 ATOM 4277 O O . ILE A 1 544 ? 63.465 87.352 -26.470 1.00 13.75 ? 544 ILE A O 1 ATOM 4278 C CB . ILE A 1 544 ? 61.380 88.782 -24.914 1.00 15.61 ? 544 ILE A CB 1 ATOM 4279 C CG1 . ILE A 1 544 ? 60.043 88.959 -24.170 1.00 16.55 ? 544 ILE A CG1 1 ATOM 4280 C CG2 . ILE A 1 544 ? 61.876 90.143 -25.479 1.00 14.92 ? 544 ILE A CG2 1 ATOM 4281 C CD1 . ILE A 1 544 ? 60.053 90.043 -23.122 1.00 19.35 ? 544 ILE A CD1 1 ATOM 4282 N N . LEU A 1 545 ? 62.109 87.806 -28.224 1.00 14.75 ? 545 LEU A N 1 ATOM 4283 C CA . LEU A 1 545 ? 63.139 87.697 -29.246 1.00 16.36 ? 545 LEU A CA 1 ATOM 4284 C C . LEU A 1 545 ? 63.267 89.037 -29.970 1.00 17.80 ? 545 LEU A C 1 ATOM 4285 O O . LEU A 1 545 ? 62.337 89.820 -29.983 1.00 18.07 ? 545 LEU A O 1 ATOM 4286 C CB . LEU A 1 545 ? 62.760 86.584 -30.257 1.00 14.55 ? 545 LEU A CB 1 ATOM 4287 C CG . LEU A 1 545 ? 62.536 85.154 -29.714 1.00 15.21 ? 545 LEU A CG 1 ATOM 4288 C CD1 . LEU A 1 545 ? 62.089 84.226 -30.848 1.00 11.44 ? 545 LEU A CD1 1 ATOM 4289 C CD2 . LEU A 1 545 ? 63.833 84.625 -29.077 1.00 13.02 ? 545 LEU A CD2 1 ATOM 4290 N N . GLY A 1 546 ? 64.415 89.295 -30.579 1.00 18.22 ? 546 GLY A N 1 ATOM 4291 C CA . GLY A 1 546 ? 64.574 90.552 -31.275 1.00 19.57 ? 546 GLY A CA 1 ATOM 4292 C C . GLY A 1 546 ? 65.993 90.662 -31.781 1.00 20.05 ? 546 GLY A C 1 ATOM 4293 O O . GLY A 1 546 ? 66.920 90.226 -31.121 1.00 18.77 ? 546 GLY A O 1 ATOM 4294 N N . GLU A 1 547 ? 66.167 91.272 -32.942 1.00 22.40 ? 547 GLU A N 1 ATOM 4295 C CA . GLU A 1 547 ? 67.507 91.430 -33.525 1.00 24.23 ? 547 GLU A CA 1 ATOM 4296 C C . GLU A 1 547 ? 68.482 92.095 -32.545 1.00 23.30 ? 547 GLU A C 1 ATOM 4297 O O . GLU A 1 547 ? 69.668 91.759 -32.499 1.00 23.36 ? 547 GLU A O 1 ATOM 4298 C CB . GLU A 1 547 ? 67.427 92.268 -34.801 1.00 27.91 ? 547 GLU A CB 1 ATOM 4299 C CG . GLU A 1 547 ? 68.745 92.304 -35.581 1.00 34.48 ? 547 GLU A CG 1 ATOM 4300 C CD . GLU A 1 547 ? 68.736 93.323 -36.726 1.00 38.08 ? 547 GLU A CD 1 ATOM 4301 O OE1 . GLU A 1 547 ? 67.709 93.397 -37.456 1.00 39.41 ? 547 GLU A OE1 1 ATOM 4302 O OE2 . GLU A 1 547 ? 69.764 94.037 -36.899 1.00 39.97 ? 547 GLU A OE2 1 ATOM 4303 N N . ASP A 1 548 ? 67.974 93.023 -31.743 1.00 21.85 ? 548 ASP A N 1 ATOM 4304 C CA . ASP A 1 548 ? 68.814 93.734 -30.779 1.00 21.30 ? 548 ASP A CA 1 ATOM 4305 C C . ASP A 1 548 ? 68.770 93.175 -29.363 1.00 20.80 ? 548 ASP A C 1 ATOM 4306 O O . ASP A 1 548 ? 69.176 93.866 -28.419 1.00 21.58 ? 548 ASP A O 1 ATOM 4307 C CB . ASP A 1 548 ? 68.421 95.211 -30.734 1.00 22.43 ? 548 ASP A CB 1 ATOM 4308 C CG . ASP A 1 548 ? 68.658 95.901 -32.042 1.00 23.31 ? 548 ASP A CG 1 ATOM 4309 O OD1 . ASP A 1 548 ? 69.813 95.954 -32.479 1.00 25.62 ? 548 ASP A OD1 1 ATOM 4310 O OD2 . ASP A 1 548 ? 67.694 96.381 -32.644 1.00 25.02 ? 548 ASP A OD2 1 ATOM 4311 N N . ILE A 1 549 ? 68.281 91.951 -29.192 1.00 18.42 ? 549 ILE A N 1 ATOM 4312 C CA . ILE A 1 549 ? 68.240 91.381 -27.853 1.00 18.74 ? 549 ILE A CA 1 ATOM 4313 C C . ILE A 1 549 ? 68.532 89.867 -27.803 1.00 18.09 ? 549 ILE A C 1 ATOM 4314 O O . ILE A 1 549 ? 69.374 89.416 -27.018 1.00 16.49 ? 549 ILE A O 1 ATOM 4315 C CB . ILE A 1 549 ? 66.871 91.686 -27.146 1.00 19.69 ? 549 ILE A CB 1 ATOM 4316 C CG1 . ILE A 1 549 ? 66.738 90.861 -25.861 1.00 22.92 ? 549 ILE A CG1 1 ATOM 4317 C CG2 . ILE A 1 549 ? 65.705 91.333 -28.027 1.00 19.95 ? 549 ILE A CG2 1 ATOM 4318 C CD1 . ILE A 1 549 ? 66.783 91.667 -24.571 1.00 25.04 ? 549 ILE A CD1 1 ATOM 4319 N N . LEU A 1 550 ? 67.858 89.092 -28.646 1.00 15.84 ? 550 LEU A N 1 ATOM 4320 C CA . LEU A 1 550 ? 68.024 87.641 -28.641 1.00 16.53 ? 550 LEU A CA 1 ATOM 4321 C C . LEU A 1 550 ? 67.401 87.069 -29.901 1.00 15.91 ? 550 LEU A C 1 ATOM 4322 O O . LEU A 1 550 ? 66.207 87.228 -30.152 1.00 17.52 ? 550 LEU A O 1 ATOM 4323 C CB . LEU A 1 550 ? 67.320 87.053 -27.407 1.00 16.97 ? 550 LEU A CB 1 ATOM 4324 C CG . LEU A 1 550 ? 67.421 85.546 -27.207 1.00 16.09 ? 550 LEU A CG 1 ATOM 4325 C CD1 . LEU A 1 550 ? 68.880 85.222 -26.909 1.00 16.07 ? 550 LEU A CD1 1 ATOM 4326 C CD2 . LEU A 1 550 ? 66.510 85.110 -26.067 1.00 14.75 ? 550 LEU A CD2 1 ATOM 4327 N N . PRO A 1 551 ? 68.202 86.388 -30.721 1.00 16.46 ? 551 PRO A N 1 ATOM 4328 C CA . PRO A 1 551 ? 67.616 85.841 -31.938 1.00 15.77 ? 551 PRO A CA 1 ATOM 4329 C C . PRO A 1 551 ? 66.810 84.537 -31.850 1.00 15.73 ? 551 PRO A C 1 ATOM 4330 O O . PRO A 1 551 ? 65.939 84.299 -32.703 1.00 15.96 ? 551 PRO A O 1 ATOM 4331 C CB . PRO A 1 551 ? 68.818 85.723 -32.879 1.00 16.65 ? 551 PRO A CB 1 ATOM 4332 C CG . PRO A 1 551 ? 69.959 85.508 -31.978 1.00 18.18 ? 551 PRO A CG 1 ATOM 4333 C CD . PRO A 1 551 ? 69.678 86.301 -30.720 1.00 16.88 ? 551 PRO A CD 1 ATOM 4334 N N . SER A 1 552 ? 67.063 83.705 -30.840 1.00 13.06 ? 552 SER A N 1 ATOM 4335 C CA . SER A 1 552 ? 66.359 82.428 -30.783 1.00 12.73 ? 552 SER A CA 1 ATOM 4336 C C . SER A 1 552 ? 66.248 81.927 -29.369 1.00 12.18 ? 552 SER A C 1 ATOM 4337 O O . SER A 1 552 ? 66.929 82.409 -28.481 1.00 10.97 ? 552 SER A O 1 ATOM 4338 C CB . SER A 1 552 ? 67.102 81.371 -31.596 1.00 12.29 ? 552 SER A CB 1 ATOM 4339 O OG . SER A 1 552 ? 68.355 81.085 -30.988 1.00 13.75 ? 552 SER A OG 1 ATOM 4340 N N . LYS A 1 553 ? 65.417 80.908 -29.189 1.00 12.79 ? 553 LYS A N 1 ATOM 4341 C CA . LYS A 1 553 ? 65.165 80.350 -27.864 1.00 12.09 ? 553 LYS A CA 1 ATOM 4342 C C . LYS A 1 553 ? 64.881 78.837 -27.933 1.00 12.42 ? 553 LYS A C 1 ATOM 4343 O O . LYS A 1 553 ? 64.128 78.375 -28.788 1.00 10.86 ? 553 LYS A O 1 ATOM 4344 C CB . LYS A 1 553 ? 63.957 81.082 -27.255 1.00 12.64 ? 553 LYS A CB 1 ATOM 4345 C CG . LYS A 1 553 ? 63.407 80.434 -25.962 1.00 12.41 ? 553 LYS A CG 1 ATOM 4346 C CD . LYS A 1 553 ? 64.415 80.540 -24.810 1.00 11.23 ? 553 LYS A CD 1 ATOM 4347 C CE . LYS A 1 553 ? 64.671 82.020 -24.423 1.00 11.09 ? 553 LYS A CE 1 ATOM 4348 N NZ . LYS A 1 553 ? 65.809 82.155 -23.468 1.00 8.44 ? 553 LYS A NZ 1 ATOM 4349 N N . HIS A 1 554 ? 65.497 78.068 -27.042 1.00 12.62 ? 554 HIS A N 1 ATOM 4350 C CA . HIS A 1 554 ? 65.248 76.619 -27.008 1.00 13.35 ? 554 HIS A CA 1 ATOM 4351 C C . HIS A 1 554 ? 64.055 76.358 -26.111 1.00 12.54 ? 554 HIS A C 1 ATOM 4352 O O . HIS A 1 554 ? 63.937 76.998 -25.078 1.00 12.52 ? 554 HIS A O 1 ATOM 4353 C CB . HIS A 1 554 ? 66.423 75.876 -26.379 1.00 15.12 ? 554 HIS A CB 1 ATOM 4354 C CG . HIS A 1 554 ? 67.588 75.656 -27.297 1.00 18.25 ? 554 HIS A CG 1 ATOM 4355 N ND1 . HIS A 1 554 ? 68.198 76.679 -27.987 1.00 20.68 ? 554 HIS A ND1 1 ATOM 4356 C CD2 . HIS A 1 554 ? 68.273 74.529 -27.609 1.00 19.84 ? 554 HIS A CD2 1 ATOM 4357 C CE1 . HIS A 1 554 ? 69.211 76.193 -28.687 1.00 21.61 ? 554 HIS A CE1 1 ATOM 4358 N NE2 . HIS A 1 554 ? 69.279 74.889 -28.473 1.00 21.19 ? 554 HIS A NE2 1 ATOM 4359 N N . VAL A 1 555 ? 63.191 75.418 -26.496 1.00 10.95 ? 555 VAL A N 1 ATOM 4360 C CA . VAL A 1 555 ? 62.034 75.015 -25.686 1.00 10.45 ? 555 VAL A CA 1 ATOM 4361 C C . VAL A 1 555 ? 62.093 73.497 -25.661 1.00 11.03 ? 555 VAL A C 1 ATOM 4362 O O . VAL A 1 555 ? 62.652 72.895 -26.578 1.00 11.75 ? 555 VAL A O 1 ATOM 4363 C CB . VAL A 1 555 ? 60.689 75.447 -26.277 1.00 9.23 ? 555 VAL A CB 1 ATOM 4364 C CG1 . VAL A 1 555 ? 60.549 76.985 -26.202 1.00 9.10 ? 555 VAL A CG1 1 ATOM 4365 C CG2 . VAL A 1 555 ? 60.578 74.985 -27.679 1.00 8.44 ? 555 VAL A CG2 1 ATOM 4366 N N . VAL A 1 556 ? 61.557 72.876 -24.613 1.00 9.24 ? 556 VAL A N 1 ATOM 4367 C CA . VAL A 1 556 ? 61.610 71.424 -24.505 1.00 9.09 ? 556 VAL A CA 1 ATOM 4368 C C . VAL A 1 556 ? 60.230 70.898 -24.066 1.00 9.23 ? 556 VAL A C 1 ATOM 4369 O O . VAL A 1 556 ? 59.594 71.486 -23.204 1.00 8.11 ? 556 VAL A O 1 ATOM 4370 C CB . VAL A 1 556 ? 62.677 70.986 -23.441 1.00 10.14 ? 556 VAL A CB 1 ATOM 4371 C CG1 . VAL A 1 556 ? 62.564 69.490 -23.151 1.00 8.66 ? 556 VAL A CG1 1 ATOM 4372 C CG2 . VAL A 1 556 ? 64.115 71.342 -23.922 1.00 7.45 ? 556 VAL A CG2 1 ATOM 4373 N N . MET A 1 557 ? 59.782 69.813 -24.691 1.00 8.25 ? 557 MET A N 1 ATOM 4374 C CA . MET A 1 557 ? 58.512 69.180 -24.330 1.00 8.88 ? 557 MET A CA 1 ATOM 4375 C C . MET A 1 557 ? 58.789 67.844 -23.655 1.00 8.46 ? 557 MET A C 1 ATOM 4376 O O . MET A 1 557 ? 59.692 67.110 -24.072 1.00 8.85 ? 557 MET A O 1 ATOM 4377 C CB . MET A 1 557 ? 57.652 68.937 -25.579 1.00 8.93 ? 557 MET A CB 1 ATOM 4378 C CG . MET A 1 557 ? 56.604 70.052 -25.918 1.00 6.97 ? 557 MET A CG 1 ATOM 4379 S SD . MET A 1 557 ? 57.337 71.665 -26.050 1.00 9.35 ? 557 MET A SD 1 ATOM 4380 C CE . MET A 1 557 ? 58.386 71.410 -27.554 1.00 7.41 ? 557 MET A CE 1 ATOM 4381 N N . HIS A 1 558 ? 58.014 67.508 -22.627 1.00 8.35 ? 558 HIS A N 1 ATOM 4382 C CA . HIS A 1 558 ? 58.162 66.208 -21.960 1.00 7.41 ? 558 HIS A CA 1 ATOM 4383 C C . HIS A 1 558 ? 56.848 65.440 -22.191 1.00 8.23 ? 558 HIS A C 1 ATOM 4384 O O . HIS A 1 558 ? 55.753 66.038 -22.176 1.00 7.95 ? 558 HIS A O 1 ATOM 4385 C CB . HIS A 1 558 ? 58.362 66.402 -20.467 1.00 6.78 ? 558 HIS A CB 1 ATOM 4386 C CG . HIS A 1 558 ? 58.215 65.137 -19.659 1.00 9.24 ? 558 HIS A CG 1 ATOM 4387 N ND1 . HIS A 1 558 ? 57.273 64.991 -18.660 1.00 8.09 ? 558 HIS A ND1 1 ATOM 4388 C CD2 . HIS A 1 558 ? 58.926 63.981 -19.677 1.00 8.80 ? 558 HIS A CD2 1 ATOM 4389 C CE1 . HIS A 1 558 ? 57.422 63.807 -18.093 1.00 9.38 ? 558 HIS A CE1 1 ATOM 4390 N NE2 . HIS A 1 558 ? 58.422 63.176 -18.690 1.00 10.01 ? 558 HIS A NE2 1 ATOM 4391 N N . ASN A 1 559 ? 56.957 64.129 -22.414 1.00 6.87 ? 559 ASN A N 1 ATOM 4392 C CA . ASN A 1 559 ? 55.798 63.276 -22.620 1.00 6.81 ? 559 ASN A CA 1 ATOM 4393 C C . ASN A 1 559 ? 55.828 62.184 -21.538 1.00 7.01 ? 559 ASN A C 1 ATOM 4394 O O . ASN A 1 559 ? 56.595 61.234 -21.648 1.00 6.92 ? 559 ASN A O 1 ATOM 4395 C CB . ASN A 1 559 ? 55.858 62.656 -24.032 1.00 6.75 ? 559 ASN A CB 1 ATOM 4396 C CG . ASN A 1 559 ? 54.852 61.502 -24.234 1.00 7.88 ? 559 ASN A CG 1 ATOM 4397 O OD1 . ASN A 1 559 ? 53.752 61.513 -23.685 1.00 9.02 ? 559 ASN A OD1 1 ATOM 4398 N ND2 . ASN A 1 559 ? 55.224 60.526 -25.059 1.00 6.16 ? 559 ASN A ND2 1 ATOM 4399 N N . THR A 1 560 ? 54.982 62.308 -20.510 1.00 5.89 ? 560 THR A N 1 ATOM 4400 C CA . THR A 1 560 ? 54.980 61.333 -19.420 1.00 7.83 ? 560 THR A CA 1 ATOM 4401 C C . THR A 1 560 ? 54.375 59.963 -19.785 1.00 8.52 ? 560 THR A C 1 ATOM 4402 O O . THR A 1 560 ? 54.561 58.966 -19.062 1.00 7.88 ? 560 THR A O 1 ATOM 4403 C CB . THR A 1 560 ? 54.234 61.920 -18.202 1.00 7.43 ? 560 THR A CB 1 ATOM 4404 O OG1 . THR A 1 560 ? 54.579 61.178 -17.023 1.00 8.23 ? 560 THR A OG1 1 ATOM 4405 C CG2 . THR A 1 560 ? 52.711 61.891 -18.450 1.00 7.49 ? 560 THR A CG2 1 ATOM 4406 N N . LEU A 1 561 ? 53.656 59.920 -20.907 1.00 7.67 ? 561 LEU A N 1 ATOM 4407 C CA . LEU A 1 561 ? 53.009 58.676 -21.380 1.00 7.24 ? 561 LEU A CA 1 ATOM 4408 C C . LEU A 1 561 ? 54.025 57.731 -22.024 1.00 7.12 ? 561 LEU A C 1 ATOM 4409 O O . LEU A 1 561 ? 54.965 58.168 -22.713 1.00 7.40 ? 561 LEU A O 1 ATOM 4410 C CB . LEU A 1 561 ? 51.889 59.002 -22.393 1.00 7.79 ? 561 LEU A CB 1 ATOM 4411 C CG . LEU A 1 561 ? 50.756 59.902 -21.852 1.00 8.18 ? 561 LEU A CG 1 ATOM 4412 C CD1 . LEU A 1 561 ? 49.649 60.041 -22.907 1.00 6.85 ? 561 LEU A CD1 1 ATOM 4413 C CD2 . LEU A 1 561 ? 50.179 59.282 -20.535 1.00 8.39 ? 561 LEU A CD2 1 ATOM 4414 N N . PRO A 1 562 ? 53.844 56.421 -21.828 1.00 7.47 ? 562 PRO A N 1 ATOM 4415 C CA . PRO A 1 562 ? 54.814 55.486 -22.421 1.00 8.52 ? 562 PRO A CA 1 ATOM 4416 C C . PRO A 1 562 ? 54.654 55.093 -23.879 1.00 10.35 ? 562 PRO A C 1 ATOM 4417 O O . PRO A 1 562 ? 54.749 53.912 -24.229 1.00 11.53 ? 562 PRO A O 1 ATOM 4418 C CB . PRO A 1 562 ? 54.752 54.286 -21.483 1.00 7.49 ? 562 PRO A CB 1 ATOM 4419 C CG . PRO A 1 562 ? 53.286 54.274 -21.096 1.00 6.45 ? 562 PRO A CG 1 ATOM 4420 C CD . PRO A 1 562 ? 52.932 55.734 -20.894 1.00 5.27 ? 562 PRO A CD 1 ATOM 4421 N N . HIS A 1 563 ? 54.383 56.071 -24.734 1.00 10.69 ? 563 HIS A N 1 ATOM 4422 C CA . HIS A 1 563 ? 54.319 55.820 -26.169 1.00 10.68 ? 563 HIS A CA 1 ATOM 4423 C C . HIS A 1 563 ? 54.649 57.116 -26.875 1.00 11.80 ? 563 HIS A C 1 ATOM 4424 O O . HIS A 1 563 ? 54.479 58.194 -26.302 1.00 12.74 ? 563 HIS A O 1 ATOM 4425 C CB . HIS A 1 563 ? 52.949 55.269 -26.630 1.00 10.99 ? 563 HIS A CB 1 ATOM 4426 C CG . HIS A 1 563 ? 51.771 56.115 -26.249 1.00 10.84 ? 563 HIS A CG 1 ATOM 4427 N ND1 . HIS A 1 563 ? 50.969 55.829 -25.158 1.00 9.56 ? 563 HIS A ND1 1 ATOM 4428 C CD2 . HIS A 1 563 ? 51.233 57.210 -26.839 1.00 10.71 ? 563 HIS A CD2 1 ATOM 4429 C CE1 . HIS A 1 563 ? 49.988 56.713 -25.097 1.00 9.56 ? 563 HIS A CE1 1 ATOM 4430 N NE2 . HIS A 1 563 ? 50.129 57.563 -26.105 1.00 11.52 ? 563 HIS A NE2 1 ATOM 4431 N N . TRP A 1 564 ? 55.188 57.005 -28.089 1.00 11.91 ? 564 TRP A N 1 ATOM 4432 C CA . TRP A 1 564 ? 55.508 58.175 -28.888 1.00 11.81 ? 564 TRP A CA 1 ATOM 4433 C C . TRP A 1 564 ? 54.249 59.016 -28.963 1.00 12.01 ? 564 TRP A C 1 ATOM 4434 O O . TRP A 1 564 ? 53.148 58.471 -29.083 1.00 12.02 ? 564 TRP A O 1 ATOM 4435 C CB . TRP A 1 564 ? 55.921 57.750 -30.291 1.00 11.93 ? 564 TRP A CB 1 ATOM 4436 C CG . TRP A 1 564 ? 57.342 57.341 -30.369 1.00 10.12 ? 564 TRP A CG 1 ATOM 4437 C CD1 . TRP A 1 564 ? 57.854 56.070 -30.240 1.00 11.99 ? 564 TRP A CD1 1 ATOM 4438 C CD2 . TRP A 1 564 ? 58.462 58.221 -30.528 1.00 11.04 ? 564 TRP A CD2 1 ATOM 4439 N NE1 . TRP A 1 564 ? 59.235 56.115 -30.307 1.00 13.38 ? 564 TRP A NE1 1 ATOM 4440 C CE2 . TRP A 1 564 ? 59.634 57.424 -30.482 1.00 10.71 ? 564 TRP A CE2 1 ATOM 4441 C CE3 . TRP A 1 564 ? 58.588 59.613 -30.705 1.00 11.48 ? 564 TRP A CE3 1 ATOM 4442 C CZ2 . TRP A 1 564 ? 60.916 57.966 -30.606 1.00 9.53 ? 564 TRP A CZ2 1 ATOM 4443 C CZ3 . TRP A 1 564 ? 59.885 60.161 -30.835 1.00 10.53 ? 564 TRP A CZ3 1 ATOM 4444 C CH2 . TRP A 1 564 ? 61.021 59.336 -30.785 1.00 11.00 ? 564 TRP A CH2 1 ATOM 4445 N N . ARG A 1 565 ? 54.374 60.329 -28.845 1.00 11.35 ? 565 ARG A N 1 ATOM 4446 C CA . ARG A 1 565 ? 53.161 61.135 -28.907 1.00 11.50 ? 565 ARG A CA 1 ATOM 4447 C C . ARG A 1 565 ? 53.354 62.427 -29.659 1.00 11.36 ? 565 ARG A C 1 ATOM 4448 O O . ARG A 1 565 ? 54.390 63.093 -29.519 1.00 12.36 ? 565 ARG A O 1 ATOM 4449 C CB . ARG A 1 565 ? 52.635 61.458 -27.491 1.00 10.84 ? 565 ARG A CB 1 ATOM 4450 C CG . ARG A 1 565 ? 51.442 62.402 -27.499 1.00 11.50 ? 565 ARG A CG 1 ATOM 4451 C CD . ARG A 1 565 ? 50.553 62.277 -26.248 1.00 12.23 ? 565 ARG A CD 1 ATOM 4452 N NE . ARG A 1 565 ? 51.287 62.591 -25.036 1.00 13.21 ? 565 ARG A NE 1 ATOM 4453 C CZ . ARG A 1 565 ? 50.749 63.090 -23.932 1.00 13.62 ? 565 ARG A CZ 1 ATOM 4454 N NH1 . ARG A 1 565 ? 49.444 63.348 -23.881 1.00 13.52 ? 565 ARG A NH1 1 ATOM 4455 N NH2 . ARG A 1 565 ? 51.533 63.312 -22.871 1.00 11.82 ? 565 ARG A NH2 1 ATOM 4456 N N . GLU A 1 566 ? 52.376 62.776 -30.487 1.00 11.32 ? 566 GLU A N 1 ATOM 4457 C CA . GLU A 1 566 ? 52.435 64.058 -31.180 1.00 12.81 ? 566 GLU A CA 1 ATOM 4458 C C . GLU A 1 566 ? 51.298 64.885 -30.588 1.00 13.67 ? 566 GLU A C 1 ATOM 4459 O O . GLU A 1 566 ? 50.215 64.343 -30.294 1.00 12.76 ? 566 GLU A O 1 ATOM 4460 C CB . GLU A 1 566 ? 52.216 63.924 -32.700 1.00 14.14 ? 566 GLU A CB 1 ATOM 4461 C CG . GLU A 1 566 ? 53.358 63.251 -33.436 1.00 14.74 ? 566 GLU A CG 1 ATOM 4462 C CD . GLU A 1 566 ? 53.132 63.250 -34.941 1.00 17.29 ? 566 GLU A CD 1 ATOM 4463 O OE1 . GLU A 1 566 ? 51.996 62.980 -35.391 1.00 16.97 ? 566 GLU A OE1 1 ATOM 4464 O OE2 . GLU A 1 566 ? 54.097 63.524 -35.673 1.00 19.03 ? 566 GLU A OE2 1 ATOM 4465 N N . GLN A 1 567 ? 51.544 66.178 -30.393 1.00 12.59 ? 567 GLN A N 1 ATOM 4466 C CA . GLN A 1 567 ? 50.524 67.082 -29.872 1.00 12.09 ? 567 GLN A CA 1 ATOM 4467 C C . GLN A 1 567 ? 50.916 68.511 -30.245 1.00 11.89 ? 567 GLN A C 1 ATOM 4468 O O . GLN A 1 567 ? 52.114 68.860 -30.246 1.00 10.10 ? 567 GLN A O 1 ATOM 4469 C CB . GLN A 1 567 ? 50.437 66.959 -28.329 1.00 14.75 ? 567 GLN A CB 1 ATOM 4470 C CG . GLN A 1 567 ? 49.342 67.837 -27.669 1.00 15.54 ? 567 GLN A CG 1 ATOM 4471 C CD . GLN A 1 567 ? 49.683 68.244 -26.215 1.00 17.91 ? 567 GLN A CD 1 ATOM 4472 O OE1 . GLN A 1 567 ? 49.713 67.412 -25.307 1.00 16.29 ? 567 GLN A OE1 1 ATOM 4473 N NE2 . GLN A 1 567 ? 49.953 69.542 -26.008 1.00 18.53 ? 567 GLN A NE2 1 ATOM 4474 N N . LEU A 1 568 ? 49.936 69.338 -30.590 1.00 10.71 ? 568 LEU A N 1 ATOM 4475 C CA . LEU A 1 568 ? 50.263 70.730 -30.887 1.00 10.64 ? 568 LEU A CA 1 ATOM 4476 C C . LEU A 1 568 ? 50.605 71.407 -29.563 1.00 10.48 ? 568 LEU A C 1 ATOM 4477 O O . LEU A 1 568 ? 49.993 71.126 -28.537 1.00 10.24 ? 568 LEU A O 1 ATOM 4478 C CB . LEU A 1 568 ? 49.068 71.459 -31.553 1.00 12.13 ? 568 LEU A CB 1 ATOM 4479 C CG . LEU A 1 568 ? 48.634 71.006 -32.975 1.00 13.85 ? 568 LEU A CG 1 ATOM 4480 C CD1 . LEU A 1 568 ? 47.621 71.993 -33.564 1.00 13.11 ? 568 LEU A CD1 1 ATOM 4481 C CD2 . LEU A 1 568 ? 49.867 70.986 -33.884 1.00 12.97 ? 568 LEU A CD2 1 ATOM 4482 N N . VAL A 1 569 ? 51.612 72.268 -29.575 1.00 10.75 ? 569 VAL A N 1 ATOM 4483 C CA . VAL A 1 569 ? 51.991 73.021 -28.393 1.00 10.96 ? 569 VAL A CA 1 ATOM 4484 C C . VAL A 1 569 ? 52.054 74.492 -28.806 1.00 10.81 ? 569 VAL A C 1 ATOM 4485 O O . VAL A 1 569 ? 52.310 74.801 -29.957 1.00 11.36 ? 569 VAL A O 1 ATOM 4486 C CB . VAL A 1 569 ? 53.367 72.569 -27.836 1.00 10.21 ? 569 VAL A CB 1 ATOM 4487 C CG1 . VAL A 1 569 ? 53.238 71.147 -27.265 1.00 10.41 ? 569 VAL A CG1 1 ATOM 4488 C CG2 . VAL A 1 569 ? 54.455 72.628 -28.937 1.00 11.39 ? 569 VAL A CG2 1 ATOM 4489 N N . ASP A 1 570 ? 51.760 75.399 -27.888 1.00 12.50 ? 570 ASP A N 1 ATOM 4490 C CA . ASP A 1 570 ? 51.831 76.811 -28.238 1.00 13.38 ? 570 ASP A CA 1 ATOM 4491 C C . ASP A 1 570 ? 52.658 77.582 -27.225 1.00 11.89 ? 570 ASP A C 1 ATOM 4492 O O . ASP A 1 570 ? 52.815 77.163 -26.060 1.00 11.71 ? 570 ASP A O 1 ATOM 4493 C CB . ASP A 1 570 ? 50.413 77.397 -28.406 1.00 16.63 ? 570 ASP A CB 1 ATOM 4494 C CG . ASP A 1 570 ? 49.628 77.495 -27.088 1.00 20.19 ? 570 ASP A CG 1 ATOM 4495 O OD1 . ASP A 1 570 ? 49.560 76.517 -26.354 1.00 25.75 ? 570 ASP A OD1 1 ATOM 4496 O OD2 . ASP A 1 570 ? 49.067 78.557 -26.787 1.00 24.23 ? 570 ASP A OD2 1 ATOM 4497 N N . PHE A 1 571 ? 53.247 78.678 -27.679 1.00 9.83 ? 571 PHE A N 1 ATOM 4498 C CA . PHE A 1 571 ? 54.039 79.526 -26.806 1.00 11.43 ? 571 PHE A CA 1 ATOM 4499 C C . PHE A 1 571 ? 53.744 80.966 -27.203 1.00 11.82 ? 571 PHE A C 1 ATOM 4500 O O . PHE A 1 571 ? 53.392 81.226 -28.358 1.00 11.57 ? 571 PHE A O 1 ATOM 4501 C CB . PHE A 1 571 ? 55.554 79.323 -27.030 1.00 10.38 ? 571 PHE A CB 1 ATOM 4502 C CG . PHE A 1 571 ? 56.051 77.971 -26.651 1.00 9.56 ? 571 PHE A CG 1 ATOM 4503 C CD1 . PHE A 1 571 ? 55.957 76.902 -27.536 1.00 9.12 ? 571 PHE A CD1 1 ATOM 4504 C CD2 . PHE A 1 571 ? 56.565 77.751 -25.387 1.00 9.19 ? 571 PHE A CD2 1 ATOM 4505 C CE1 . PHE A 1 571 ? 56.371 75.609 -27.147 1.00 8.30 ? 571 PHE A CE1 1 ATOM 4506 C CE2 . PHE A 1 571 ? 56.978 76.466 -24.997 1.00 9.80 ? 571 PHE A CE2 1 ATOM 4507 C CZ . PHE A 1 571 ? 56.873 75.405 -25.891 1.00 7.74 ? 571 PHE A CZ 1 ATOM 4508 N N . TYR A 1 572 ? 53.909 81.886 -26.265 1.00 12.07 ? 572 TYR A N 1 ATOM 4509 C CA . TYR A 1 572 ? 53.755 83.299 -26.581 1.00 13.37 ? 572 TYR A CA 1 ATOM 4510 C C . TYR A 1 572 ? 55.127 83.785 -27.025 1.00 13.24 ? 572 TYR A C 1 ATOM 4511 O O . TYR A 1 572 ? 56.137 83.442 -26.394 1.00 13.03 ? 572 TYR A O 1 ATOM 4512 C CB . TYR A 1 572 ? 53.340 84.114 -25.351 1.00 14.63 ? 572 TYR A CB 1 ATOM 4513 C CG . TYR A 1 572 ? 51.907 83.951 -24.904 1.00 16.53 ? 572 TYR A CG 1 ATOM 4514 C CD1 . TYR A 1 572 ? 50.989 83.263 -25.677 1.00 16.72 ? 572 TYR A CD1 1 ATOM 4515 C CD2 . TYR A 1 572 ? 51.469 84.510 -23.696 1.00 19.70 ? 572 TYR A CD2 1 ATOM 4516 C CE1 . TYR A 1 572 ? 49.672 83.124 -25.292 1.00 17.72 ? 572 TYR A CE1 1 ATOM 4517 C CE2 . TYR A 1 572 ? 50.134 84.377 -23.282 1.00 20.94 ? 572 TYR A CE2 1 ATOM 4518 C CZ . TYR A 1 572 ? 49.239 83.681 -24.101 1.00 19.47 ? 572 TYR A CZ 1 ATOM 4519 O OH . TYR A 1 572 ? 47.914 83.563 -23.746 1.00 19.80 ? 572 TYR A OH 1 ATOM 4520 N N . VAL A 1 573 ? 55.165 84.577 -28.100 1.00 13.10 ? 573 VAL A N 1 ATOM 4521 C CA . VAL A 1 573 ? 56.415 85.155 -28.616 1.00 12.17 ? 573 VAL A CA 1 ATOM 4522 C C . VAL A 1 573 ? 56.185 86.662 -28.868 1.00 13.19 ? 573 VAL A C 1 ATOM 4523 O O . VAL A 1 573 ? 55.053 87.089 -29.098 1.00 12.77 ? 573 VAL A O 1 ATOM 4524 C CB . VAL A 1 573 ? 56.904 84.482 -29.942 1.00 13.07 ? 573 VAL A CB 1 ATOM 4525 C CG1 . VAL A 1 573 ? 57.435 83.079 -29.666 1.00 12.45 ? 573 VAL A CG1 1 ATOM 4526 C CG2 . VAL A 1 573 ? 55.791 84.439 -30.966 1.00 12.10 ? 573 VAL A CG2 1 ATOM 4527 N N . SER A 1 574 ? 57.254 87.459 -28.829 1.00 13.51 ? 574 SER A N 1 ATOM 4528 C CA . SER A 1 574 ? 57.134 88.909 -28.989 1.00 13.87 ? 574 SER A CA 1 ATOM 4529 C C . SER A 1 574 ? 57.096 89.402 -30.439 1.00 15.50 ? 574 SER A C 1 ATOM 4530 O O . SER A 1 574 ? 57.121 90.606 -30.699 1.00 15.34 ? 574 SER A O 1 ATOM 4531 C CB . SER A 1 574 ? 58.273 89.599 -28.217 1.00 13.30 ? 574 SER A CB 1 ATOM 4532 O OG . SER A 1 574 ? 59.526 89.237 -28.758 1.00 14.12 ? 574 SER A OG 1 ATOM 4533 N N . SER A 1 575 ? 57.022 88.470 -31.383 1.00 15.51 ? 575 SER A N 1 ATOM 4534 C CA . SER A 1 575 ? 56.977 88.821 -32.794 1.00 16.35 ? 575 SER A CA 1 ATOM 4535 C C . SER A 1 575 ? 56.295 87.709 -33.538 1.00 16.59 ? 575 SER A C 1 ATOM 4536 O O . SER A 1 575 ? 56.439 86.529 -33.187 1.00 17.54 ? 575 SER A O 1 ATOM 4537 C CB . SER A 1 575 ? 58.392 88.977 -33.369 1.00 16.25 ? 575 SER A CB 1 ATOM 4538 O OG . SER A 1 575 ? 58.409 88.796 -34.785 1.00 15.75 ? 575 SER A OG 1 ATOM 4539 N N . PRO A 1 576 ? 55.546 88.058 -34.582 1.00 17.23 ? 576 PRO A N 1 ATOM 4540 C CA . PRO A 1 576 ? 54.849 87.035 -35.378 1.00 16.12 ? 576 PRO A CA 1 ATOM 4541 C C . PRO A 1 576 ? 55.805 86.371 -36.375 1.00 16.20 ? 576 PRO A C 1 ATOM 4542 O O . PRO A 1 576 ? 55.482 85.347 -36.971 1.00 16.78 ? 576 PRO A O 1 ATOM 4543 C CB . PRO A 1 576 ? 53.759 87.843 -36.089 1.00 17.73 ? 576 PRO A CB 1 ATOM 4544 C CG . PRO A 1 576 ? 54.514 89.183 -36.385 1.00 18.49 ? 576 PRO A CG 1 ATOM 4545 C CD . PRO A 1 576 ? 55.239 89.431 -35.049 1.00 16.83 ? 576 PRO A CD 1 ATOM 4546 N N . PHE A 1 577 ? 56.989 86.943 -36.567 1.00 16.05 ? 577 PHE A N 1 ATOM 4547 C CA . PHE A 1 577 ? 57.928 86.383 -37.544 1.00 16.80 ? 577 PHE A CA 1 ATOM 4548 C C . PHE A 1 577 ? 58.891 85.414 -36.859 1.00 16.15 ? 577 PHE A C 1 ATOM 4549 O O . PHE A 1 577 ? 60.070 85.725 -36.632 1.00 14.32 ? 577 PHE A O 1 ATOM 4550 C CB . PHE A 1 577 ? 58.686 87.515 -38.226 1.00 17.43 ? 577 PHE A CB 1 ATOM 4551 C CG . PHE A 1 577 ? 57.786 88.521 -38.883 1.00 19.03 ? 577 PHE A CG 1 ATOM 4552 C CD1 . PHE A 1 577 ? 57.963 89.893 -38.650 1.00 20.70 ? 577 PHE A CD1 1 ATOM 4553 C CD2 . PHE A 1 577 ? 56.775 88.107 -39.744 1.00 19.10 ? 577 PHE A CD2 1 ATOM 4554 C CE1 . PHE A 1 577 ? 57.133 90.836 -39.278 1.00 21.38 ? 577 PHE A CE1 1 ATOM 4555 C CE2 . PHE A 1 577 ? 55.943 89.024 -40.379 1.00 20.64 ? 577 PHE A CE2 1 ATOM 4556 C CZ . PHE A 1 577 ? 56.120 90.399 -40.149 1.00 21.74 ? 577 PHE A CZ 1 ATOM 4557 N N . VAL A 1 578 ? 58.374 84.219 -36.581 1.00 14.43 ? 578 VAL A N 1 ATOM 4558 C CA . VAL A 1 578 ? 59.131 83.207 -35.850 1.00 14.44 ? 578 VAL A CA 1 ATOM 4559 C C . VAL A 1 578 ? 58.993 81.879 -36.532 1.00 13.92 ? 578 VAL A C 1 ATOM 4560 O O . VAL A 1 578 ? 57.913 81.520 -36.991 1.00 14.03 ? 578 VAL A O 1 ATOM 4561 C CB . VAL A 1 578 ? 58.597 83.090 -34.374 1.00 13.31 ? 578 VAL A CB 1 ATOM 4562 C CG1 . VAL A 1 578 ? 59.309 81.949 -33.591 1.00 13.64 ? 578 VAL A CG1 1 ATOM 4563 C CG2 . VAL A 1 578 ? 58.811 84.410 -33.656 1.00 13.40 ? 578 VAL A CG2 1 ATOM 4564 N N . SER A 1 579 ? 60.092 81.156 -36.629 1.00 13.77 ? 579 SER A N 1 ATOM 4565 C CA . SER A 1 579 ? 60.022 79.851 -37.238 1.00 15.83 ? 579 SER A CA 1 ATOM 4566 C C . SER A 1 579 ? 60.549 78.828 -36.236 1.00 14.78 ? 579 SER A C 1 ATOM 4567 O O . SER A 1 579 ? 61.292 79.145 -35.312 1.00 17.15 ? 579 SER A O 1 ATOM 4568 C CB . SER A 1 579 ? 60.794 79.827 -38.568 1.00 16.92 ? 579 SER A CB 1 ATOM 4569 O OG . SER A 1 579 ? 62.059 80.423 -38.395 1.00 20.36 ? 579 SER A OG 1 ATOM 4570 N N . VAL A 1 580 ? 60.173 77.592 -36.444 1.00 13.80 ? 580 VAL A N 1 ATOM 4571 C CA . VAL A 1 580 ? 60.534 76.533 -35.549 1.00 12.81 ? 580 VAL A CA 1 ATOM 4572 C C . VAL A 1 580 ? 61.358 75.481 -36.284 1.00 13.66 ? 580 VAL A C 1 ATOM 4573 O O . VAL A 1 580 ? 61.124 75.201 -37.449 1.00 13.59 ? 580 VAL A O 1 ATOM 4574 C CB . VAL A 1 580 ? 59.234 75.866 -35.009 1.00 13.44 ? 580 VAL A CB 1 ATOM 4575 C CG1 . VAL A 1 580 ? 59.566 74.744 -34.023 1.00 11.32 ? 580 VAL A CG1 1 ATOM 4576 C CG2 . VAL A 1 580 ? 58.336 76.922 -34.380 1.00 11.05 ? 580 VAL A CG2 1 ATOM 4577 N N . THR A 1 581 ? 62.320 74.913 -35.585 1.00 13.64 ? 581 THR A N 1 ATOM 4578 C CA . THR A 1 581 ? 63.154 73.848 -36.110 1.00 15.34 ? 581 THR A CA 1 ATOM 4579 C C . THR A 1 581 ? 63.390 72.874 -34.954 1.00 15.61 ? 581 THR A C 1 ATOM 4580 O O . THR A 1 581 ? 63.228 73.254 -33.785 1.00 14.31 ? 581 THR A O 1 ATOM 4581 C CB . THR A 1 581 ? 64.547 74.359 -36.542 1.00 16.16 ? 581 THR A CB 1 ATOM 4582 O OG1 . THR A 1 581 ? 65.065 75.218 -35.525 1.00 16.35 ? 581 THR A OG1 1 ATOM 4583 C CG2 . THR A 1 581 ? 64.483 75.111 -37.891 1.00 16.05 ? 581 THR A CG2 1 ATOM 4584 N N . ASP A 1 582 ? 63.768 71.636 -35.277 1.00 16.00 ? 582 ASP A N 1 ATOM 4585 C CA . ASP A 1 582 ? 64.113 70.668 -34.245 1.00 17.86 ? 582 ASP A CA 1 ATOM 4586 C C . ASP A 1 582 ? 65.620 70.779 -34.015 1.00 19.31 ? 582 ASP A C 1 ATOM 4587 O O . ASP A 1 582 ? 66.253 71.647 -34.604 1.00 18.44 ? 582 ASP A O 1 ATOM 4588 C CB . ASP A 1 582 ? 63.697 69.243 -34.625 1.00 18.02 ? 582 ASP A CB 1 ATOM 4589 C CG . ASP A 1 582 ? 64.370 68.705 -35.888 1.00 17.40 ? 582 ASP A CG 1 ATOM 4590 O OD1 . ASP A 1 582 ? 63.818 67.697 -36.399 1.00 18.09 ? 582 ASP A OD1 1 ATOM 4591 O OD2 . ASP A 1 582 ? 65.418 69.233 -36.353 1.00 14.94 ? 582 ASP A OD2 1 ATOM 4592 N N . LEU A 1 583 ? 66.234 69.935 -33.187 1.00 22.48 ? 583 LEU A N 1 ATOM 4593 C CA . LEU A 1 583 ? 67.671 70.182 -32.989 1.00 24.37 ? 583 LEU A CA 1 ATOM 4594 C C . LEU A 1 583 ? 68.584 69.717 -34.120 1.00 24.29 ? 583 LEU A C 1 ATOM 4595 O O . LEU A 1 583 ? 69.777 70.036 -34.106 1.00 25.40 ? 583 LEU A O 1 ATOM 4596 C CB . LEU A 1 583 ? 68.183 69.655 -31.624 1.00 26.66 ? 583 LEU A CB 1 ATOM 4597 C CG . LEU A 1 583 ? 69.105 70.679 -30.932 1.00 26.41 ? 583 LEU A CG 1 ATOM 4598 C CD1 . LEU A 1 583 ? 68.340 71.974 -30.681 1.00 26.66 ? 583 LEU A CD1 1 ATOM 4599 C CD2 . LEU A 1 583 ? 69.624 70.150 -29.631 1.00 28.91 ? 583 LEU A CD2 1 ATOM 4600 N N . ALA A 1 584 ? 68.036 68.991 -35.101 1.00 23.50 ? 584 ALA A N 1 ATOM 4601 C CA . ALA A 1 584 ? 68.821 68.581 -36.275 1.00 21.78 ? 584 ALA A CA 1 ATOM 4602 C C . ALA A 1 584 ? 68.650 69.717 -37.286 1.00 21.40 ? 584 ALA A C 1 ATOM 4603 O O . ALA A 1 584 ? 69.100 69.657 -38.444 1.00 20.22 ? 584 ALA A O 1 ATOM 4604 C CB . ALA A 1 584 ? 68.278 67.292 -36.860 1.00 21.64 ? 584 ALA A CB 1 ATOM 4605 N N . ASN A 1 585 ? 67.954 70.750 -36.839 1.00 21.20 ? 585 ASN A N 1 ATOM 4606 C CA . ASN A 1 585 ? 67.693 71.918 -37.652 1.00 21.54 ? 585 ASN A CA 1 ATOM 4607 C C . ASN A 1 585 ? 66.703 71.712 -38.794 1.00 21.15 ? 585 ASN A C 1 ATOM 4608 O O . ASN A 1 585 ? 66.720 72.463 -39.760 1.00 20.80 ? 585 ASN A O 1 ATOM 4609 C CB . ASN A 1 585 ? 68.998 72.471 -38.206 1.00 25.66 ? 585 ASN A CB 1 ATOM 4610 C CG . ASN A 1 585 ? 69.253 73.867 -37.743 1.00 28.81 ? 585 ASN A CG 1 ATOM 4611 O OD1 . ASN A 1 585 ? 68.472 74.772 -38.028 1.00 29.59 ? 585 ASN A OD1 1 ATOM 4612 N ND2 . ASN A 1 585 ? 70.336 74.056 -37.001 1.00 32.14 ? 585 ASN A ND2 1 ATOM 4613 N N . ASN A 1 586 ? 65.863 70.690 -38.703 1.00 18.79 ? 586 ASN A N 1 ATOM 4614 C CA . ASN A 1 586 ? 64.859 70.478 -39.713 1.00 19.55 ? 586 ASN A CA 1 ATOM 4615 C C . ASN A 1 586 ? 63.720 71.458 -39.398 1.00 19.54 ? 586 ASN A C 1 ATOM 4616 O O . ASN A 1 586 ? 63.357 71.657 -38.224 1.00 17.62 ? 586 ASN A O 1 ATOM 4617 C CB . ASN A 1 586 ? 64.280 69.074 -39.638 1.00 20.49 ? 586 ASN A CB 1 ATOM 4618 C CG . ASN A 1 586 ? 65.329 67.991 -39.770 1.00 22.72 ? 586 ASN A CG 1 ATOM 4619 O OD1 . ASN A 1 586 ? 66.232 68.079 -40.605 1.00 22.27 ? 586 ASN A OD1 1 ATOM 4620 N ND2 . ASN A 1 586 ? 65.210 66.949 -38.940 1.00 24.02 ? 586 ASN A ND2 1 ATOM 4621 N N . PRO A 1 587 ? 63.150 72.091 -40.435 1.00 18.85 ? 587 PRO A N 1 ATOM 4622 C CA . PRO A 1 587 ? 62.053 73.020 -40.161 1.00 17.69 ? 587 PRO A CA 1 ATOM 4623 C C . PRO A 1 587 ? 60.808 72.298 -39.698 1.00 17.21 ? 587 PRO A C 1 ATOM 4624 O O . PRO A 1 587 ? 60.574 71.139 -40.061 1.00 17.23 ? 587 PRO A O 1 ATOM 4625 C CB . PRO A 1 587 ? 61.849 73.749 -41.493 1.00 19.78 ? 587 PRO A CB 1 ATOM 4626 C CG . PRO A 1 587 ? 62.505 72.867 -42.526 1.00 20.61 ? 587 PRO A CG 1 ATOM 4627 C CD . PRO A 1 587 ? 63.697 72.293 -41.794 1.00 20.89 ? 587 PRO A CD 1 ATOM 4628 N N . VAL A 1 588 ? 60.026 72.964 -38.859 1.00 15.52 ? 588 VAL A N 1 ATOM 4629 C CA . VAL A 1 588 ? 58.782 72.391 -38.361 1.00 15.30 ? 588 VAL A CA 1 ATOM 4630 C C . VAL A 1 588 ? 57.662 73.363 -38.765 1.00 14.83 ? 588 VAL A C 1 ATOM 4631 O O . VAL A 1 588 ? 57.761 74.563 -38.500 1.00 13.53 ? 588 VAL A O 1 ATOM 4632 C CB . VAL A 1 588 ? 58.809 72.243 -36.816 1.00 15.86 ? 588 VAL A CB 1 ATOM 4633 C CG1 . VAL A 1 588 ? 57.486 71.732 -36.334 1.00 15.36 ? 588 VAL A CG1 1 ATOM 4634 C CG2 . VAL A 1 588 ? 59.924 71.267 -36.397 1.00 15.02 ? 588 VAL A CG2 1 ATOM 4635 N N . GLU A 1 589 ? 56.625 72.856 -39.430 1.00 14.98 ? 589 GLU A N 1 ATOM 4636 C CA . GLU A 1 589 ? 55.505 73.691 -39.852 1.00 15.90 ? 589 GLU A CA 1 ATOM 4637 C C . GLU A 1 589 ? 54.861 74.334 -38.605 1.00 15.27 ? 589 GLU A C 1 ATOM 4638 O O . GLU A 1 589 ? 54.531 73.631 -37.644 1.00 13.03 ? 589 GLU A O 1 ATOM 4639 C CB . GLU A 1 589 ? 54.458 72.858 -40.590 1.00 17.76 ? 589 GLU A CB 1 ATOM 4640 C CG . GLU A 1 589 ? 53.645 73.666 -41.592 1.00 25.60 ? 589 GLU A CG 1 ATOM 4641 C CD . GLU A 1 589 ? 52.294 73.033 -41.918 1.00 29.49 ? 589 GLU A CD 1 ATOM 4642 O OE1 . GLU A 1 589 ? 52.229 71.778 -41.971 1.00 33.87 ? 589 GLU A OE1 1 ATOM 4643 O OE2 . GLU A 1 589 ? 51.298 73.783 -42.118 1.00 31.46 ? 589 GLU A OE2 1 ATOM 4644 N N . ALA A 1 590 ? 54.671 75.648 -38.628 1.00 12.69 ? 590 ALA A N 1 ATOM 4645 C CA . ALA A 1 590 ? 54.113 76.335 -37.472 1.00 13.35 ? 590 ALA A CA 1 ATOM 4646 C C . ALA A 1 590 ? 53.026 77.278 -37.921 1.00 13.92 ? 590 ALA A C 1 ATOM 4647 O O . ALA A 1 590 ? 52.964 77.649 -39.107 1.00 12.66 ? 590 ALA A O 1 ATOM 4648 C CB . ALA A 1 590 ? 55.217 77.124 -36.757 1.00 13.54 ? 590 ALA A CB 1 ATOM 4649 N N . GLN A 1 591 ? 52.158 77.648 -36.984 1.00 14.01 ? 591 GLN A N 1 ATOM 4650 C CA . GLN A 1 591 ? 51.077 78.602 -37.251 1.00 13.95 ? 591 GLN A CA 1 ATOM 4651 C C . GLN A 1 591 ? 51.136 79.688 -36.179 1.00 14.35 ? 591 GLN A C 1 ATOM 4652 O O . GLN A 1 591 ? 51.347 79.392 -34.986 1.00 15.15 ? 591 GLN A O 1 ATOM 4653 C CB . GLN A 1 591 ? 49.700 77.919 -37.190 1.00 14.12 ? 591 GLN A CB 1 ATOM 4654 C CG . GLN A 1 591 ? 48.504 78.888 -37.247 1.00 13.73 ? 591 GLN A CG 1 ATOM 4655 C CD . GLN A 1 591 ? 47.157 78.172 -37.021 1.00 13.77 ? 591 GLN A CD 1 ATOM 4656 O OE1 . GLN A 1 591 ? 46.922 77.080 -37.550 1.00 14.77 ? 591 GLN A OE1 1 ATOM 4657 N NE2 . GLN A 1 591 ? 46.276 78.790 -36.252 1.00 11.17 ? 591 GLN A NE2 1 ATOM 4658 N N . VAL A 1 592 ? 50.953 80.936 -36.586 1.00 12.80 ? 592 VAL A N 1 ATOM 4659 C CA . VAL A 1 592 ? 50.930 82.030 -35.628 1.00 12.69 ? 592 VAL A CA 1 ATOM 4660 C C . VAL A 1 592 ? 49.511 82.578 -35.599 1.00 11.82 ? 592 VAL A C 1 ATOM 4661 O O . VAL A 1 592 ? 48.867 82.701 -36.628 1.00 13.17 ? 592 VAL A O 1 ATOM 4662 C CB . VAL A 1 592 ? 51.983 83.146 -35.978 1.00 12.95 ? 592 VAL A CB 1 ATOM 4663 C CG1 . VAL A 1 592 ? 51.733 84.430 -35.140 1.00 11.28 ? 592 VAL A CG1 1 ATOM 4664 C CG2 . VAL A 1 592 ? 53.371 82.628 -35.638 1.00 11.95 ? 592 VAL A CG2 1 ATOM 4665 N N . SER A 1 593 ? 49.026 82.866 -34.405 1.00 12.92 ? 593 SER A N 1 ATOM 4666 C CA . SER A 1 593 ? 47.687 83.403 -34.166 1.00 13.96 ? 593 SER A CA 1 ATOM 4667 C C . SER A 1 593 ? 47.839 84.541 -33.175 1.00 14.60 ? 593 SER A C 1 ATOM 4668 O O . SER A 1 593 ? 48.853 84.633 -32.465 1.00 15.82 ? 593 SER A O 1 ATOM 4669 C CB . SER A 1 593 ? 46.763 82.323 -33.535 1.00 13.91 ? 593 SER A CB 1 ATOM 4670 O OG . SER A 1 593 ? 46.569 81.186 -34.389 1.00 15.56 ? 593 SER A OG 1 ATOM 4671 N N . PRO A 1 594 ? 46.840 85.434 -33.100 1.00 15.55 ? 594 PRO A N 1 ATOM 4672 C CA . PRO A 1 594 ? 46.936 86.545 -32.141 1.00 14.68 ? 594 PRO A CA 1 ATOM 4673 C C . PRO A 1 594 ? 46.692 86.027 -30.721 1.00 15.65 ? 594 PRO A C 1 ATOM 4674 O O . PRO A 1 594 ? 46.311 84.857 -30.536 1.00 15.10 ? 594 PRO A O 1 ATOM 4675 C CB . PRO A 1 594 ? 45.812 87.495 -32.566 1.00 13.57 ? 594 PRO A CB 1 ATOM 4676 C CG . PRO A 1 594 ? 45.452 87.070 -33.988 1.00 13.90 ? 594 PRO A CG 1 ATOM 4677 C CD . PRO A 1 594 ? 45.651 85.565 -33.964 1.00 15.01 ? 594 PRO A CD 1 ATOM 4678 N N . VAL A 1 595 ? 46.936 86.888 -29.728 1.00 13.86 ? 595 VAL A N 1 ATOM 4679 C CA . VAL A 1 595 ? 46.654 86.554 -28.336 1.00 14.23 ? 595 VAL A CA 1 ATOM 4680 C C . VAL A 1 595 ? 45.370 87.367 -28.096 1.00 13.83 ? 595 VAL A C 1 ATOM 4681 O O . VAL A 1 595 ? 45.384 88.605 -28.126 1.00 13.97 ? 595 VAL A O 1 ATOM 4682 C CB . VAL A 1 595 ? 47.734 87.063 -27.350 1.00 13.17 ? 595 VAL A CB 1 ATOM 4683 C CG1 . VAL A 1 595 ? 47.263 86.814 -25.872 1.00 12.83 ? 595 VAL A CG1 1 ATOM 4684 C CG2 . VAL A 1 595 ? 49.022 86.338 -27.585 1.00 15.93 ? 595 VAL A CG2 1 ATOM 4685 N N . TRP A 1 596 ? 44.268 86.658 -27.881 1.00 14.74 ? 596 TRP A N 1 ATOM 4686 C CA . TRP A 1 596 ? 42.963 87.270 -27.678 1.00 15.82 ? 596 TRP A CA 1 ATOM 4687 C C . TRP A 1 596 ? 42.550 87.168 -26.212 1.00 16.62 ? 596 TRP A C 1 ATOM 4688 O O . TRP A 1 596 ? 42.645 86.087 -25.632 1.00 15.32 ? 596 TRP A O 1 ATOM 4689 C CB . TRP A 1 596 ? 41.875 86.549 -28.513 1.00 14.43 ? 596 TRP A CB 1 ATOM 4690 C CG . TRP A 1 596 ? 41.986 86.713 -30.016 1.00 13.88 ? 596 TRP A CG 1 ATOM 4691 C CD1 . TRP A 1 596 ? 42.400 85.769 -30.933 1.00 13.54 ? 596 TRP A CD1 1 ATOM 4692 C CD2 . TRP A 1 596 ? 41.705 87.899 -30.761 1.00 13.38 ? 596 TRP A CD2 1 ATOM 4693 N NE1 . TRP A 1 596 ? 42.390 86.310 -32.206 1.00 14.27 ? 596 TRP A NE1 1 ATOM 4694 C CE2 . TRP A 1 596 ? 41.973 87.613 -32.128 1.00 12.86 ? 596 TRP A CE2 1 ATOM 4695 C CE3 . TRP A 1 596 ? 41.251 89.187 -30.406 1.00 12.84 ? 596 TRP A CE3 1 ATOM 4696 C CZ2 . TRP A 1 596 ? 41.801 88.565 -33.138 1.00 14.26 ? 596 TRP A CZ2 1 ATOM 4697 C CZ3 . TRP A 1 596 ? 41.080 90.134 -31.413 1.00 13.40 ? 596 TRP A CZ3 1 ATOM 4698 C CH2 . TRP A 1 596 ? 41.354 89.816 -32.762 1.00 13.89 ? 596 TRP A CH2 1 ATOM 4699 N N . SER A 1 597 ? 42.120 88.284 -25.622 1.00 16.65 ? 597 SER A N 1 ATOM 4700 C CA . SER A 1 597 ? 41.614 88.250 -24.250 1.00 18.43 ? 597 SER A CA 1 ATOM 4701 C C . SER A 1 597 ? 40.214 88.859 -24.231 1.00 18.25 ? 597 SER A C 1 ATOM 4702 O O . SER A 1 597 ? 39.959 89.873 -24.880 1.00 18.54 ? 597 SER A O 1 ATOM 4703 C CB . SER A 1 597 ? 42.541 88.979 -23.276 1.00 19.66 ? 597 SER A CB 1 ATOM 4704 O OG . SER A 1 597 ? 43.021 90.170 -23.821 1.00 24.04 ? 597 SER A OG 1 ATOM 4705 N N . TRP A 1 598 ? 39.306 88.232 -23.499 1.00 17.37 ? 598 TRP A N 1 ATOM 4706 C CA . TRP A 1 598 ? 37.931 88.702 -23.443 1.00 18.45 ? 598 TRP A CA 1 ATOM 4707 C C . TRP A 1 598 ? 37.667 89.636 -22.286 1.00 20.50 ? 598 TRP A C 1 ATOM 4708 O O . TRP A 1 598 ? 38.074 89.379 -21.165 1.00 20.82 ? 598 TRP A O 1 ATOM 4709 C CB . TRP A 1 598 ? 36.969 87.509 -23.404 1.00 16.49 ? 598 TRP A CB 1 ATOM 4710 C CG . TRP A 1 598 ? 36.959 86.743 -24.708 1.00 14.25 ? 598 TRP A CG 1 ATOM 4711 C CD1 . TRP A 1 598 ? 37.898 85.856 -25.151 1.00 14.32 ? 598 TRP A CD1 1 ATOM 4712 C CD2 . TRP A 1 598 ? 35.953 86.799 -25.712 1.00 13.47 ? 598 TRP A CD2 1 ATOM 4713 N NE1 . TRP A 1 598 ? 37.527 85.341 -26.383 1.00 12.41 ? 598 TRP A NE1 1 ATOM 4714 C CE2 . TRP A 1 598 ? 36.335 85.904 -26.745 1.00 12.77 ? 598 TRP A CE2 1 ATOM 4715 C CE3 . TRP A 1 598 ? 34.756 87.519 -25.845 1.00 13.37 ? 598 TRP A CE3 1 ATOM 4716 C CZ2 . TRP A 1 598 ? 35.570 85.710 -27.879 1.00 12.54 ? 598 TRP A CZ2 1 ATOM 4717 C CZ3 . TRP A 1 598 ? 33.995 87.324 -26.981 1.00 13.35 ? 598 TRP A CZ3 1 ATOM 4718 C CH2 . TRP A 1 598 ? 34.407 86.424 -27.986 1.00 11.24 ? 598 TRP A CH2 1 ATOM 4719 N N . HIS A 1 599 ? 36.980 90.730 -22.559 1.00 23.12 ? 599 HIS A N 1 ATOM 4720 C CA . HIS A 1 599 ? 36.726 91.704 -21.511 1.00 26.82 ? 599 HIS A CA 1 ATOM 4721 C C . HIS A 1 599 ? 35.263 92.008 -21.336 1.00 27.76 ? 599 HIS A C 1 ATOM 4722 O O . HIS A 1 599 ? 34.551 92.138 -22.324 1.00 27.13 ? 599 HIS A O 1 ATOM 4723 C CB . HIS A 1 599 ? 37.462 93.011 -21.852 1.00 29.84 ? 599 HIS A CB 1 ATOM 4724 C CG . HIS A 1 599 ? 38.950 92.847 -21.937 1.00 32.98 ? 599 HIS A CG 1 ATOM 4725 N ND1 . HIS A 1 599 ? 39.692 92.297 -20.913 1.00 34.42 ? 599 HIS A ND1 1 ATOM 4726 C CD2 . HIS A 1 599 ? 39.819 93.056 -22.957 1.00 34.65 ? 599 HIS A CD2 1 ATOM 4727 C CE1 . HIS A 1 599 ? 40.948 92.161 -21.301 1.00 34.88 ? 599 HIS A CE1 1 ATOM 4728 N NE2 . HIS A 1 599 ? 41.053 92.613 -22.538 1.00 35.73 ? 599 HIS A NE2 1 ATOM 4729 N N . HIS A 1 600 ? 34.788 92.086 -20.098 1.00 29.69 ? 600 HIS A N 1 ATOM 4730 C CA . HIS A 1 600 ? 33.393 92.486 -19.946 1.00 32.01 ? 600 HIS A CA 1 ATOM 4731 C C . HIS A 1 600 ? 33.484 93.994 -19.923 1.00 30.48 ? 600 HIS A C 1 ATOM 4732 O O . HIS A 1 600 ? 33.901 94.575 -18.932 1.00 30.74 ? 600 HIS A O 1 ATOM 4733 C CB . HIS A 1 600 ? 32.726 92.044 -18.649 1.00 35.84 ? 600 HIS A CB 1 ATOM 4734 C CG . HIS A 1 600 ? 31.357 92.646 -18.484 1.00 40.90 ? 600 HIS A CG 1 ATOM 4735 N ND1 . HIS A 1 600 ? 30.250 92.170 -19.159 1.00 43.15 ? 600 HIS A ND1 1 ATOM 4736 C CD2 . HIS A 1 600 ? 30.950 93.782 -17.860 1.00 42.82 ? 600 HIS A CD2 1 ATOM 4737 C CE1 . HIS A 1 600 ? 29.226 92.987 -18.967 1.00 43.92 ? 600 HIS A CE1 1 ATOM 4738 N NE2 . HIS A 1 600 ? 29.625 93.975 -18.183 1.00 44.27 ? 600 HIS A NE2 1 ATOM 4739 N N . ASP A 1 601 ? 33.116 94.618 -21.028 1.00 30.01 ? 601 ASP A N 1 ATOM 4740 C CA . ASP A 1 601 ? 33.174 96.061 -21.159 1.00 30.39 ? 601 ASP A CA 1 ATOM 4741 C C . ASP A 1 601 ? 32.041 96.707 -20.332 1.00 30.37 ? 601 ASP A C 1 ATOM 4742 O O . ASP A 1 601 ? 30.894 96.699 -20.755 1.00 29.50 ? 601 ASP A O 1 ATOM 4743 C CB . ASP A 1 601 ? 33.015 96.395 -22.632 1.00 31.58 ? 601 ASP A CB 1 ATOM 4744 C CG . ASP A 1 601 ? 33.443 97.802 -22.972 1.00 32.45 ? 601 ASP A CG 1 ATOM 4745 O OD1 . ASP A 1 601 ? 33.045 98.766 -22.279 1.00 32.60 ? 601 ASP A OD1 1 ATOM 4746 O OD2 . ASP A 1 601 ? 34.172 97.939 -23.972 1.00 33.62 ? 601 ASP A OD2 1 ATOM 4747 N N . THR A 1 602 ? 32.364 97.262 -19.165 1.00 31.04 ? 602 THR A N 1 ATOM 4748 C CA . THR A 1 602 ? 31.342 97.889 -18.321 1.00 32.61 ? 602 THR A CA 1 ATOM 4749 C C . THR A 1 602 ? 30.739 99.133 -18.938 1.00 32.37 ? 602 THR A C 1 ATOM 4750 O O . THR A 1 602 ? 29.680 99.585 -18.497 1.00 33.89 ? 602 THR A O 1 ATOM 4751 C CB . THR A 1 602 ? 31.866 98.280 -16.939 1.00 34.27 ? 602 THR A CB 1 ATOM 4752 O OG1 . THR A 1 602 ? 33.030 99.122 -17.081 1.00 35.79 ? 602 THR A OG1 1 ATOM 4753 C CG2 . THR A 1 602 ? 32.166 97.027 -16.120 1.00 34.69 ? 602 THR A CG2 1 ATOM 4754 N N . LEU A 1 603 ? 31.396 99.675 -19.957 1.00 31.10 ? 603 LEU A N 1 ATOM 4755 C CA . LEU A 1 603 ? 30.884 100.847 -20.641 1.00 30.07 ? 603 LEU A CA 1 ATOM 4756 C C . LEU A 1 603 ? 29.864 100.480 -21.735 1.00 29.05 ? 603 LEU A C 1 ATOM 4757 O O . LEU A 1 603 ? 28.716 100.918 -21.670 1.00 28.48 ? 603 LEU A O 1 ATOM 4758 C CB . LEU A 1 603 ? 32.036 101.661 -21.238 1.00 32.05 ? 603 LEU A CB 1 ATOM 4759 C CG . LEU A 1 603 ? 32.952 102.366 -20.217 1.00 33.49 ? 603 LEU A CG 1 ATOM 4760 C CD1 . LEU A 1 603 ? 32.132 103.353 -19.380 1.00 33.56 ? 603 LEU A CD1 1 ATOM 4761 C CD2 . LEU A 1 603 ? 33.604 101.322 -19.299 1.00 34.85 ? 603 LEU A CD2 1 ATOM 4762 N N . THR A 1 604 ? 30.270 99.684 -22.728 1.00 26.54 ? 604 THR A N 1 ATOM 4763 C CA . THR A 1 604 ? 29.353 99.279 -23.802 1.00 24.17 ? 604 THR A CA 1 ATOM 4764 C C . THR A 1 604 ? 28.440 98.148 -23.347 1.00 22.02 ? 604 THR A C 1 ATOM 4765 O O . THR A 1 604 ? 27.523 97.766 -24.069 1.00 21.61 ? 604 THR A O 1 ATOM 4766 C CB . THR A 1 604 ? 30.108 98.751 -25.032 1.00 24.91 ? 604 THR A CB 1 ATOM 4767 O OG1 . THR A 1 604 ? 30.928 97.630 -24.630 1.00 25.42 ? 604 THR A OG1 1 ATOM 4768 C CG2 . THR A 1 604 ? 30.989 99.869 -25.656 1.00 24.24 ? 604 THR A CG2 1 ATOM 4769 N N . LYS A 1 605 ? 28.700 97.607 -22.164 1.00 21.16 ? 605 LYS A N 1 ATOM 4770 C CA . LYS A 1 605 ? 27.915 96.493 -21.631 1.00 20.76 ? 605 LYS A CA 1 ATOM 4771 C C . LYS A 1 605 ? 27.911 95.304 -22.586 1.00 20.88 ? 605 LYS A C 1 ATOM 4772 O O . LYS A 1 605 ? 26.857 94.753 -22.853 1.00 20.89 ? 605 LYS A O 1 ATOM 4773 C CB . LYS A 1 605 ? 26.443 96.901 -21.377 1.00 21.33 ? 605 LYS A CB 1 ATOM 4774 C CG . LYS A 1 605 ? 26.275 97.994 -20.342 1.00 21.61 ? 605 LYS A CG 1 ATOM 4775 C CD . LYS A 1 605 ? 26.743 97.528 -18.941 1.00 24.58 ? 605 LYS A CD 1 ATOM 4776 C CE . LYS A 1 605 ? 26.709 98.721 -17.965 1.00 24.15 ? 605 LYS A CE 1 ATOM 4777 N NZ . LYS A 1 605 ? 27.208 98.435 -16.588 1.00 27.67 ? 605 LYS A NZ 1 ATOM 4778 N N . THR A 1 606 ? 29.075 94.937 -23.123 1.00 20.91 ? 606 THR A N 1 ATOM 4779 C CA . THR A 1 606 ? 29.209 93.787 -24.019 1.00 19.63 ? 606 THR A CA 1 ATOM 4780 C C . THR A 1 606 ? 30.452 93.008 -23.579 1.00 19.51 ? 606 THR A C 1 ATOM 4781 O O . THR A 1 606 ? 31.253 93.509 -22.789 1.00 20.00 ? 606 THR A O 1 ATOM 4782 C CB . THR A 1 606 ? 29.393 94.217 -25.486 1.00 20.75 ? 606 THR A CB 1 ATOM 4783 O OG1 . THR A 1 606 ? 30.564 95.052 -25.598 1.00 21.10 ? 606 THR A OG1 1 ATOM 4784 C CG2 . THR A 1 606 ? 28.149 94.956 -25.976 1.00 18.98 ? 606 THR A CG2 1 ATOM 4785 N N . ILE A 1 607 ? 30.588 91.773 -24.053 1.00 18.41 ? 607 ILE A N 1 ATOM 4786 C CA . ILE A 1 607 ? 31.751 90.949 -23.729 1.00 17.04 ? 607 ILE A CA 1 ATOM 4787 C C . ILE A 1 607 ? 32.380 90.729 -25.104 1.00 17.25 ? 607 ILE A C 1 ATOM 4788 O O . ILE A 1 607 ? 31.797 90.059 -25.956 1.00 15.39 ? 607 ILE A O 1 ATOM 4789 C CB . ILE A 1 607 ? 31.325 89.624 -23.100 1.00 17.68 ? 607 ILE A CB 1 ATOM 4790 C CG1 . ILE A 1 607 ? 30.458 89.899 -21.868 1.00 18.07 ? 607 ILE A CG1 1 ATOM 4791 C CG2 . ILE A 1 607 ? 32.580 88.834 -22.686 1.00 17.42 ? 607 ILE A CG2 1 ATOM 4792 C CD1 . ILE A 1 607 ? 29.593 88.754 -21.424 1.00 17.87 ? 607 ILE A CD1 1 ATOM 4793 N N . HIS A 1 608 ? 33.558 91.310 -25.327 1.00 17.54 ? 608 HIS A N 1 ATOM 4794 C CA . HIS A 1 608 ? 34.210 91.233 -26.636 1.00 18.15 ? 608 HIS A CA 1 ATOM 4795 C C . HIS A 1 608 ? 35.702 91.030 -26.479 1.00 17.50 ? 608 HIS A C 1 ATOM 4796 O O . HIS A 1 608 ? 36.281 91.361 -25.431 1.00 18.72 ? 608 HIS A O 1 ATOM 4797 C CB . HIS A 1 608 ? 33.925 92.504 -27.411 1.00 20.84 ? 608 HIS A CB 1 ATOM 4798 C CG . HIS A 1 608 ? 34.359 93.730 -26.690 1.00 23.96 ? 608 HIS A CG 1 ATOM 4799 N ND1 . HIS A 1 608 ? 35.445 94.481 -27.086 1.00 27.14 ? 608 HIS A ND1 1 ATOM 4800 C CD2 . HIS A 1 608 ? 33.894 94.309 -25.559 1.00 24.89 ? 608 HIS A CD2 1 ATOM 4801 C CE1 . HIS A 1 608 ? 35.629 95.474 -26.231 1.00 25.98 ? 608 HIS A CE1 1 ATOM 4802 N NE2 . HIS A 1 608 ? 34.702 95.391 -25.293 1.00 27.27 ? 608 HIS A NE2 1 ATOM 4803 N N . PRO A 1 609 ? 36.365 90.503 -27.522 1.00 16.42 ? 609 PRO A N 1 ATOM 4804 C CA . PRO A 1 609 ? 37.805 90.263 -27.402 1.00 16.70 ? 609 PRO A CA 1 ATOM 4805 C C . PRO A 1 609 ? 38.720 91.381 -27.860 1.00 17.21 ? 609 PRO A C 1 ATOM 4806 O O . PRO A 1 609 ? 38.382 92.125 -28.768 1.00 17.72 ? 609 PRO A O 1 ATOM 4807 C CB . PRO A 1 609 ? 37.991 88.999 -28.229 1.00 16.66 ? 609 PRO A CB 1 ATOM 4808 C CG . PRO A 1 609 ? 37.097 89.306 -29.427 1.00 16.65 ? 609 PRO A CG 1 ATOM 4809 C CD . PRO A 1 609 ? 35.852 89.988 -28.803 1.00 17.10 ? 609 PRO A CD 1 ATOM 4810 N N . GLN A 1 610 ? 39.887 91.473 -27.236 1.00 17.70 ? 610 GLN A N 1 ATOM 4811 C CA . GLN A 1 610 ? 40.877 92.487 -27.584 1.00 20.15 ? 610 GLN A CA 1 ATOM 4812 C C . GLN A 1 610 ? 42.109 91.712 -27.951 1.00 18.39 ? 610 GLN A C 1 ATOM 4813 O O . GLN A 1 610 ? 42.432 90.729 -27.288 1.00 17.99 ? 610 GLN A O 1 ATOM 4814 C CB . GLN A 1 610 ? 41.183 93.379 -26.378 1.00 23.86 ? 610 GLN A CB 1 ATOM 4815 C CG . GLN A 1 610 ? 39.967 94.092 -25.834 1.00 31.23 ? 610 GLN A CG 1 ATOM 4816 C CD . GLN A 1 610 ? 39.425 95.143 -26.792 1.00 35.12 ? 610 GLN A CD 1 ATOM 4817 O OE1 . GLN A 1 610 ? 38.925 94.826 -27.890 1.00 38.26 ? 610 GLN A OE1 1 ATOM 4818 N NE2 . GLN A 1 610 ? 39.524 96.411 -26.387 1.00 37.78 ? 610 GLN A NE2 1 ATOM 4819 N N . GLY A 1 611 ? 42.786 92.138 -29.007 1.00 17.69 ? 611 GLY A N 1 ATOM 4820 C CA . GLY A 1 611 ? 43.990 91.441 -29.424 1.00 16.55 ? 611 GLY A CA 1 ATOM 4821 C C . GLY A 1 611 ? 45.250 92.161 -28.967 1.00 17.45 ? 611 GLY A C 1 ATOM 4822 O O . GLY A 1 611 ? 45.276 93.396 -28.900 1.00 16.29 ? 611 GLY A O 1 ATOM 4823 N N . SER A 1 612 ? 46.290 91.405 -28.629 1.00 17.94 ? 612 SER A N 1 ATOM 4824 C CA . SER A 1 612 ? 47.560 92.006 -28.203 1.00 18.39 ? 612 SER A CA 1 ATOM 4825 C C . SER A 1 612 ? 48.258 92.543 -29.448 1.00 19.18 ? 612 SER A C 1 ATOM 4826 O O . SER A 1 612 ? 48.151 91.946 -30.521 1.00 18.37 ? 612 SER A O 1 ATOM 4827 C CB . SER A 1 612 ? 48.470 90.947 -27.564 1.00 18.21 ? 612 SER A CB 1 ATOM 4828 O OG . SER A 1 612 ? 49.789 91.456 -27.404 1.00 17.29 ? 612 SER A OG 1 ATOM 4829 N N . THR A 1 613 ? 48.936 93.687 -29.328 1.00 20.60 ? 613 THR A N 1 ATOM 4830 C CA . THR A 1 613 ? 49.679 94.227 -30.459 1.00 22.01 ? 613 THR A CA 1 ATOM 4831 C C . THR A 1 613 ? 51.178 93.950 -30.241 1.00 23.78 ? 613 THR A C 1 ATOM 4832 O O . THR A 1 613 ? 52.015 94.294 -31.094 1.00 23.73 ? 613 THR A O 1 ATOM 4833 C CB . THR A 1 613 ? 49.488 95.747 -30.601 1.00 22.63 ? 613 THR A CB 1 ATOM 4834 O OG1 . THR A 1 613 ? 49.927 96.373 -29.394 1.00 22.88 ? 613 THR A OG1 1 ATOM 4835 C CG2 . THR A 1 613 ? 48.006 96.098 -30.834 1.00 21.79 ? 613 THR A CG2 1 ATOM 4836 N N . THR A 1 614 ? 51.512 93.296 -29.119 1.00 24.63 ? 614 THR A N 1 ATOM 4837 C CA . THR A 1 614 ? 52.912 92.981 -28.809 1.00 24.44 ? 614 THR A CA 1 ATOM 4838 C C . THR A 1 614 ? 53.266 91.501 -28.532 1.00 24.25 ? 614 THR A C 1 ATOM 4839 O O . THR A 1 614 ? 54.449 91.164 -28.431 1.00 24.37 ? 614 THR A O 1 ATOM 4840 C CB . THR A 1 614 ? 53.349 93.778 -27.620 1.00 24.52 ? 614 THR A CB 1 ATOM 4841 O OG1 . THR A 1 614 ? 52.441 93.517 -26.546 1.00 25.91 ? 614 THR A OG1 1 ATOM 4842 C CG2 . THR A 1 614 ? 53.339 95.286 -27.960 1.00 26.58 ? 614 THR A CG2 1 ATOM 4843 N N . LYS A 1 615 ? 52.271 90.636 -28.358 1.00 22.23 ? 615 LYS A N 1 ATOM 4844 C CA . LYS A 1 615 ? 52.552 89.224 -28.124 1.00 21.76 ? 615 LYS A CA 1 ATOM 4845 C C . LYS A 1 615 ? 51.686 88.463 -29.094 1.00 20.50 ? 615 LYS A C 1 ATOM 4846 O O . LYS A 1 615 ? 50.580 88.914 -29.453 1.00 19.33 ? 615 LYS A O 1 ATOM 4847 C CB . LYS A 1 615 ? 52.158 88.748 -26.722 1.00 23.30 ? 615 LYS A CB 1 ATOM 4848 C CG . LYS A 1 615 ? 52.161 89.781 -25.638 1.00 27.74 ? 615 LYS A CG 1 ATOM 4849 C CD . LYS A 1 615 ? 52.026 89.127 -24.237 1.00 28.10 ? 615 LYS A CD 1 ATOM 4850 C CE . LYS A 1 615 ? 50.883 88.100 -24.157 1.00 29.48 ? 615 LYS A CE 1 ATOM 4851 N NZ . LYS A 1 615 ? 50.643 87.684 -22.740 1.00 29.15 ? 615 LYS A NZ 1 ATOM 4852 N N . TYR A 1 616 ? 52.176 87.290 -29.472 1.00 18.10 ? 616 TYR A N 1 ATOM 4853 C CA . TYR A 1 616 ? 51.487 86.416 -30.410 1.00 17.48 ? 616 TYR A CA 1 ATOM 4854 C C . TYR A 1 616 ? 51.657 84.981 -29.984 1.00 15.63 ? 616 TYR A C 1 ATOM 4855 O O . TYR A 1 616 ? 52.566 84.675 -29.222 1.00 14.69 ? 616 TYR A O 1 ATOM 4856 C CB . TYR A 1 616 ? 52.059 86.598 -31.823 1.00 16.69 ? 616 TYR A CB 1 ATOM 4857 C CG . TYR A 1 616 ? 52.077 88.054 -32.248 1.00 19.00 ? 616 TYR A CG 1 ATOM 4858 C CD1 . TYR A 1 616 ? 53.154 88.882 -31.897 1.00 18.47 ? 616 TYR A CD1 1 ATOM 4859 C CD2 . TYR A 1 616 ? 50.960 88.636 -32.889 1.00 18.38 ? 616 TYR A CD2 1 ATOM 4860 C CE1 . TYR A 1 616 ? 53.127 90.228 -32.153 1.00 20.06 ? 616 TYR A CE1 1 ATOM 4861 C CE2 . TYR A 1 616 ? 50.921 89.992 -33.151 1.00 18.79 ? 616 TYR A CE2 1 ATOM 4862 C CZ . TYR A 1 616 ? 52.005 90.782 -32.775 1.00 20.28 ? 616 TYR A CZ 1 ATOM 4863 O OH . TYR A 1 616 ? 51.973 92.134 -32.955 1.00 23.25 ? 616 TYR A OH 1 ATOM 4864 N N . ARG A 1 617 ? 50.784 84.105 -30.486 1.00 15.86 ? 617 ARG A N 1 ATOM 4865 C CA . ARG A 1 617 ? 50.843 82.675 -30.183 1.00 15.21 ? 617 ARG A CA 1 ATOM 4866 C C . ARG A 1 617 ? 51.483 81.909 -31.323 1.00 14.50 ? 617 ARG A C 1 ATOM 4867 O O . ARG A 1 617 ? 51.078 82.072 -32.479 1.00 15.26 ? 617 ARG A O 1 ATOM 4868 C CB . ARG A 1 617 ? 49.455 82.098 -29.988 1.00 16.37 ? 617 ARG A CB 1 ATOM 4869 C CG . ARG A 1 617 ? 48.806 82.361 -28.656 1.00 18.91 ? 617 ARG A CG 1 ATOM 4870 C CD . ARG A 1 617 ? 47.394 81.727 -28.586 1.00 19.97 ? 617 ARG A CD 1 ATOM 4871 N NE . ARG A 1 617 ? 47.389 80.262 -28.545 1.00 19.48 ? 617 ARG A NE 1 ATOM 4872 C CZ . ARG A 1 617 ? 46.784 79.475 -29.437 1.00 21.01 ? 617 ARG A CZ 1 ATOM 4873 N NH1 . ARG A 1 617 ? 46.129 79.992 -30.470 1.00 22.60 ? 617 ARG A NH1 1 ATOM 4874 N NH2 . ARG A 1 617 ? 46.791 78.160 -29.283 1.00 18.83 ? 617 ARG A NH2 1 ATOM 4875 N N . ILE A 1 618 ? 52.494 81.096 -31.043 1.00 12.99 ? 618 ILE A N 1 ATOM 4876 C CA . ILE A 1 618 ? 53.057 80.298 -32.131 1.00 12.31 ? 618 ILE A CA 1 ATOM 4877 C C . ILE A 1 618 ? 52.702 78.872 -31.774 1.00 11.17 ? 618 ILE A C 1 ATOM 4878 O O . ILE A 1 618 ? 52.858 78.465 -30.630 1.00 11.21 ? 618 ILE A O 1 ATOM 4879 C CB . ILE A 1 618 ? 54.589 80.481 -32.345 1.00 12.07 ? 618 ILE A CB 1 ATOM 4880 C CG1 . ILE A 1 618 ? 55.008 79.601 -33.532 1.00 14.21 ? 618 ILE A CG1 1 ATOM 4881 C CG2 . ILE A 1 618 ? 55.383 80.155 -31.105 1.00 12.63 ? 618 ILE A CG2 1 ATOM 4882 C CD1 . ILE A 1 618 ? 56.325 79.970 -34.189 1.00 13.88 ? 618 ILE A CD1 1 ATOM 4883 N N . ILE A 1 619 ? 52.200 78.135 -32.757 1.00 10.00 ? 619 ILE A N 1 ATOM 4884 C CA . ILE A 1 619 ? 51.727 76.763 -32.578 1.00 11.08 ? 619 ILE A CA 1 ATOM 4885 C C . ILE A 1 619 ? 52.417 75.793 -33.538 1.00 11.45 ? 619 ILE A C 1 ATOM 4886 O O . ILE A 1 619 ? 52.496 76.062 -34.735 1.00 11.79 ? 619 ILE A O 1 ATOM 4887 C CB . ILE A 1 619 ? 50.207 76.706 -32.898 1.00 12.50 ? 619 ILE A CB 1 ATOM 4888 C CG1 . ILE A 1 619 ? 49.483 77.813 -32.114 1.00 15.71 ? 619 ILE A CG1 1 ATOM 4889 C CG2 . ILE A 1 619 ? 49.655 75.333 -32.636 1.00 12.25 ? 619 ILE A CG2 1 ATOM 4890 C CD1 . ILE A 1 619 ? 48.163 78.335 -32.816 1.00 16.86 ? 619 ILE A CD1 1 ATOM 4891 N N . PHE A 1 620 ? 52.871 74.657 -33.031 1.00 9.87 ? 620 PHE A N 1 ATOM 4892 C CA . PHE A 1 620 ? 53.500 73.668 -33.884 1.00 10.17 ? 620 PHE A CA 1 ATOM 4893 C C . PHE A 1 620 ? 53.341 72.306 -33.249 1.00 10.80 ? 620 PHE A C 1 ATOM 4894 O O . PHE A 1 620 ? 53.088 72.208 -32.056 1.00 11.66 ? 620 PHE A O 1 ATOM 4895 C CB . PHE A 1 620 ? 54.986 73.972 -34.108 1.00 7.68 ? 620 PHE A CB 1 ATOM 4896 C CG . PHE A 1 620 ? 55.834 73.866 -32.869 1.00 8.51 ? 620 PHE A CG 1 ATOM 4897 C CD1 . PHE A 1 620 ? 56.466 72.670 -32.544 1.00 9.00 ? 620 PHE A CD1 1 ATOM 4898 C CD2 . PHE A 1 620 ? 56.052 74.972 -32.059 1.00 6.91 ? 620 PHE A CD2 1 ATOM 4899 C CE1 . PHE A 1 620 ? 57.313 72.560 -31.430 1.00 7.82 ? 620 PHE A CE1 1 ATOM 4900 C CE2 . PHE A 1 620 ? 56.908 74.887 -30.931 1.00 9.32 ? 620 PHE A CE2 1 ATOM 4901 C CZ . PHE A 1 620 ? 57.541 73.662 -30.621 1.00 7.20 ? 620 PHE A CZ 1 ATOM 4902 N N . LYS A 1 621 ? 53.474 71.272 -34.070 1.00 11.13 ? 621 LYS A N 1 ATOM 4903 C CA . LYS A 1 621 ? 53.352 69.892 -33.634 1.00 12.14 ? 621 LYS A CA 1 ATOM 4904 C C . LYS A 1 621 ? 54.643 69.360 -33.017 1.00 11.55 ? 621 LYS A C 1 ATOM 4905 O O . LYS A 1 621 ? 55.677 69.271 -33.698 1.00 10.95 ? 621 LYS A O 1 ATOM 4906 C CB . LYS A 1 621 ? 52.944 69.024 -34.842 1.00 12.66 ? 621 LYS A CB 1 ATOM 4907 C CG . LYS A 1 621 ? 52.643 67.564 -34.524 1.00 13.77 ? 621 LYS A CG 1 ATOM 4908 C CD . LYS A 1 621 ? 51.832 66.893 -35.652 1.00 16.38 ? 621 LYS A CD 1 ATOM 4909 C CE . LYS A 1 621 ? 52.553 66.958 -36.988 1.00 21.20 ? 621 LYS A CE 1 ATOM 4910 N NZ . LYS A 1 621 ? 51.828 66.210 -38.093 1.00 23.26 ? 621 LYS A NZ 1 ATOM 4911 N N . ALA A 1 622 ? 54.610 69.024 -31.725 1.00 10.69 ? 622 ALA A N 1 ATOM 4912 C CA . ALA A 1 622 ? 55.801 68.449 -31.095 1.00 11.67 ? 622 ALA A CA 1 ATOM 4913 C C . ALA A 1 622 ? 55.697 66.925 -31.185 1.00 11.51 ? 622 ALA A C 1 ATOM 4914 O O . ALA A 1 622 ? 54.605 66.362 -31.075 1.00 13.13 ? 622 ALA A O 1 ATOM 4915 C CB . ALA A 1 622 ? 55.895 68.845 -29.623 1.00 9.75 ? 622 ALA A CB 1 ATOM 4916 N N . ARG A 1 623 ? 56.829 66.256 -31.345 1.00 12.61 ? 623 ARG A N 1 ATOM 4917 C CA . ARG A 1 623 ? 56.840 64.796 -31.414 1.00 12.34 ? 623 ARG A CA 1 ATOM 4918 C C . ARG A 1 623 ? 57.816 64.361 -30.319 1.00 10.97 ? 623 ARG A C 1 ATOM 4919 O O . ARG A 1 623 ? 58.980 64.705 -30.345 1.00 10.99 ? 623 ARG A O 1 ATOM 4920 C CB . ARG A 1 623 ? 57.274 64.305 -32.796 1.00 14.54 ? 623 ARG A CB 1 ATOM 4921 C CG . ARG A 1 623 ? 57.309 62.775 -32.862 1.00 15.54 ? 623 ARG A CG 1 ATOM 4922 C CD . ARG A 1 623 ? 57.256 62.212 -34.320 1.00 19.11 ? 623 ARG A CD 1 ATOM 4923 N NE . ARG A 1 623 ? 57.479 60.762 -34.327 1.00 18.41 ? 623 ARG A NE 1 ATOM 4924 C CZ . ARG A 1 623 ? 58.683 60.199 -34.219 1.00 20.72 ? 623 ARG A CZ 1 ATOM 4925 N NH1 . ARG A 1 623 ? 59.773 60.958 -34.120 1.00 20.97 ? 623 ARG A NH1 1 ATOM 4926 N NH2 . ARG A 1 623 ? 58.799 58.881 -34.134 1.00 22.24 ? 623 ARG A NH2 1 ATOM 4927 N N . VAL A 1 624 ? 57.318 63.617 -29.336 1.00 10.19 ? 624 VAL A N 1 ATOM 4928 C CA . VAL A 1 624 ? 58.154 63.270 -28.192 1.00 10.72 ? 624 VAL A CA 1 ATOM 4929 C C . VAL A 1 624 ? 58.208 61.788 -27.887 1.00 8.91 ? 624 VAL A C 1 ATOM 4930 O O . VAL A 1 624 ? 57.186 61.130 -27.914 1.00 8.17 ? 624 VAL A O 1 ATOM 4931 C CB . VAL A 1 624 ? 57.626 64.018 -26.936 1.00 11.52 ? 624 VAL A CB 1 ATOM 4932 C CG1 . VAL A 1 624 ? 58.656 63.942 -25.785 1.00 10.16 ? 624 VAL A CG1 1 ATOM 4933 C CG2 . VAL A 1 624 ? 57.310 65.504 -27.328 1.00 11.64 ? 624 VAL A CG2 1 ATOM 4934 N N . PRO A 1 625 ? 59.406 61.266 -27.558 1.00 8.57 ? 625 PRO A N 1 ATOM 4935 C CA . PRO A 1 625 ? 59.563 59.845 -27.244 1.00 8.11 ? 625 PRO A CA 1 ATOM 4936 C C . PRO A 1 625 ? 58.722 59.397 -26.029 1.00 9.61 ? 625 PRO A C 1 ATOM 4937 O O . PRO A 1 625 ? 58.247 60.202 -25.245 1.00 7.55 ? 625 PRO A O 1 ATOM 4938 C CB . PRO A 1 625 ? 61.066 59.712 -26.947 1.00 8.50 ? 625 PRO A CB 1 ATOM 4939 C CG . PRO A 1 625 ? 61.701 60.925 -27.686 1.00 8.29 ? 625 PRO A CG 1 ATOM 4940 C CD . PRO A 1 625 ? 60.679 61.989 -27.340 1.00 8.40 ? 625 PRO A CD 1 ATOM 4941 N N . PRO A 1 626 ? 58.512 58.082 -25.894 1.00 10.18 ? 626 PRO A N 1 ATOM 4942 C CA . PRO A 1 626 ? 57.751 57.564 -24.763 1.00 9.38 ? 626 PRO A CA 1 ATOM 4943 C C . PRO A 1 626 ? 58.512 58.040 -23.515 1.00 10.21 ? 626 PRO A C 1 ATOM 4944 O O . PRO A 1 626 ? 59.736 57.916 -23.480 1.00 9.03 ? 626 PRO A O 1 ATOM 4945 C CB . PRO A 1 626 ? 57.906 56.052 -24.902 1.00 9.15 ? 626 PRO A CB 1 ATOM 4946 C CG . PRO A 1 626 ? 58.212 55.826 -26.352 1.00 10.01 ? 626 PRO A CG 1 ATOM 4947 C CD . PRO A 1 626 ? 59.068 56.993 -26.728 1.00 8.85 ? 626 PRO A CD 1 ATOM 4948 N N . MET A 1 627 ? 57.807 58.568 -22.507 1.00 9.50 ? 627 MET A N 1 ATOM 4949 C CA . MET A 1 627 ? 58.449 58.991 -21.246 1.00 9.23 ? 627 MET A CA 1 ATOM 4950 C C . MET A 1 627 ? 59.746 59.738 -21.527 1.00 9.56 ? 627 MET A C 1 ATOM 4951 O O . MET A 1 627 ? 60.754 59.530 -20.837 1.00 6.94 ? 627 MET A O 1 ATOM 4952 C CB . MET A 1 627 ? 58.746 57.738 -20.400 1.00 9.62 ? 627 MET A CB 1 ATOM 4953 C CG . MET A 1 627 ? 57.463 56.984 -19.980 1.00 10.83 ? 627 MET A CG 1 ATOM 4954 S SD . MET A 1 627 ? 57.762 55.345 -19.250 1.00 12.46 ? 627 MET A SD 1 ATOM 4955 C CE . MET A 1 627 ? 58.603 55.744 -17.708 1.00 13.60 ? 627 MET A CE 1 ATOM 4956 N N . GLY A 1 628 ? 59.695 60.649 -22.506 1.00 10.52 ? 628 GLY A N 1 ATOM 4957 C CA . GLY A 1 628 ? 60.906 61.335 -22.934 1.00 9.21 ? 628 GLY A CA 1 ATOM 4958 C C . GLY A 1 628 ? 60.797 62.834 -23.155 1.00 10.25 ? 628 GLY A C 1 ATOM 4959 O O . GLY A 1 628 ? 59.827 63.486 -22.758 1.00 8.37 ? 628 GLY A O 1 ATOM 4960 N N . LEU A 1 629 ? 61.803 63.364 -23.837 1.00 8.87 ? 629 LEU A N 1 ATOM 4961 C CA . LEU A 1 629 ? 61.912 64.798 -24.080 1.00 9.21 ? 629 LEU A CA 1 ATOM 4962 C C . LEU A 1 629 ? 62.320 65.070 -25.536 1.00 9.13 ? 629 LEU A C 1 ATOM 4963 O O . LEU A 1 629 ? 63.018 64.253 -26.161 1.00 7.94 ? 629 LEU A O 1 ATOM 4964 C CB . LEU A 1 629 ? 62.992 65.357 -23.153 1.00 7.84 ? 629 LEU A CB 1 ATOM 4965 C CG . LEU A 1 629 ? 62.732 65.216 -21.648 1.00 11.17 ? 629 LEU A CG 1 ATOM 4966 C CD1 . LEU A 1 629 ? 64.046 65.474 -20.876 1.00 8.98 ? 629 LEU A CD1 1 ATOM 4967 C CD2 . LEU A 1 629 ? 61.684 66.261 -21.216 1.00 10.36 ? 629 LEU A CD2 1 ATOM 4968 N N . ALA A 1 630 ? 61.913 66.223 -26.051 1.00 9.51 ? 630 ALA A N 1 ATOM 4969 C CA . ALA A 1 630 ? 62.246 66.596 -27.415 1.00 9.86 ? 630 ALA A CA 1 ATOM 4970 C C . ALA A 1 630 ? 62.466 68.090 -27.371 1.00 11.00 ? 630 ALA A C 1 ATOM 4971 O O . ALA A 1 630 ? 61.663 68.821 -26.795 1.00 11.55 ? 630 ALA A O 1 ATOM 4972 C CB . ALA A 1 630 ? 61.128 66.241 -28.360 1.00 9.16 ? 630 ALA A CB 1 ATOM 4973 N N . THR A 1 631 ? 63.597 68.520 -27.931 1.00 11.93 ? 631 THR A N 1 ATOM 4974 C CA . THR A 1 631 ? 64.004 69.934 -27.934 1.00 11.14 ? 631 THR A CA 1 ATOM 4975 C C . THR A 1 631 ? 63.734 70.600 -29.276 1.00 11.99 ? 631 THR A C 1 ATOM 4976 O O . THR A 1 631 ? 63.961 69.976 -30.320 1.00 12.25 ? 631 THR A O 1 ATOM 4977 C CB . THR A 1 631 ? 65.528 70.037 -27.629 1.00 11.41 ? 631 THR A CB 1 ATOM 4978 O OG1 . THR A 1 631 ? 65.796 69.322 -26.421 1.00 9.77 ? 631 THR A OG1 1 ATOM 4979 C CG2 . THR A 1 631 ? 65.979 71.513 -27.439 1.00 11.08 ? 631 THR A CG2 1 ATOM 4980 N N . TYR A 1 632 ? 63.230 71.843 -29.243 1.00 11.13 ? 632 TYR A N 1 ATOM 4981 C CA . TYR A 1 632 ? 62.979 72.631 -30.460 1.00 10.31 ? 632 TYR A CA 1 ATOM 4982 C C . TYR A 1 632 ? 63.577 74.032 -30.261 1.00 10.83 ? 632 TYR A C 1 ATOM 4983 O O . TYR A 1 632 ? 63.906 74.412 -29.133 1.00 7.76 ? 632 TYR A O 1 ATOM 4984 C CB . TYR A 1 632 ? 61.471 72.759 -30.784 1.00 12.11 ? 632 TYR A CB 1 ATOM 4985 C CG . TYR A 1 632 ? 60.794 71.442 -31.140 1.00 11.86 ? 632 TYR A CG 1 ATOM 4986 C CD1 . TYR A 1 632 ? 60.411 70.544 -30.139 1.00 12.17 ? 632 TYR A CD1 1 ATOM 4987 C CD2 . TYR A 1 632 ? 60.590 71.071 -32.472 1.00 12.00 ? 632 TYR A CD2 1 ATOM 4988 C CE1 . TYR A 1 632 ? 59.844 69.293 -30.454 1.00 11.18 ? 632 TYR A CE1 1 ATOM 4989 C CE2 . TYR A 1 632 ? 60.003 69.799 -32.805 1.00 10.67 ? 632 TYR A CE2 1 ATOM 4990 C CZ . TYR A 1 632 ? 59.647 68.936 -31.784 1.00 11.88 ? 632 TYR A CZ 1 ATOM 4991 O OH . TYR A 1 632 ? 59.089 67.701 -32.077 1.00 12.40 ? 632 TYR A OH 1 ATOM 4992 N N . VAL A 1 633 ? 63.692 74.785 -31.357 1.00 10.55 ? 633 VAL A N 1 ATOM 4993 C CA . VAL A 1 633 ? 64.254 76.137 -31.351 1.00 11.70 ? 633 VAL A CA 1 ATOM 4994 C C . VAL A 1 633 ? 63.320 77.091 -32.111 1.00 12.11 ? 633 VAL A C 1 ATOM 4995 O O . VAL A 1 633 ? 62.870 76.770 -33.207 1.00 13.35 ? 633 VAL A O 1 ATOM 4996 C CB . VAL A 1 633 ? 65.648 76.168 -32.045 1.00 10.99 ? 633 VAL A CB 1 ATOM 4997 C CG1 . VAL A 1 633 ? 66.238 77.629 -32.058 1.00 11.23 ? 633 VAL A CG1 1 ATOM 4998 C CG2 . VAL A 1 633 ? 66.588 75.193 -31.319 1.00 11.26 ? 633 VAL A CG2 1 ATOM 4999 N N . LEU A 1 634 ? 63.017 78.232 -31.504 1.00 12.40 ? 634 LEU A N 1 ATOM 5000 C CA . LEU A 1 634 ? 62.173 79.251 -32.120 1.00 13.57 ? 634 LEU A CA 1 ATOM 5001 C C . LEU A 1 634 ? 63.140 80.372 -32.482 1.00 14.51 ? 634 LEU A C 1 ATOM 5002 O O . LEU A 1 634 ? 63.900 80.842 -31.627 1.00 13.51 ? 634 LEU A O 1 ATOM 5003 C CB . LEU A 1 634 ? 61.144 79.771 -31.135 1.00 15.37 ? 634 LEU A CB 1 ATOM 5004 C CG . LEU A 1 634 ? 60.311 78.741 -30.364 1.00 17.60 ? 634 LEU A CG 1 ATOM 5005 C CD1 . LEU A 1 634 ? 59.145 79.479 -29.722 1.00 17.65 ? 634 LEU A CD1 1 ATOM 5006 C CD2 . LEU A 1 634 ? 59.813 77.643 -31.256 1.00 15.44 ? 634 LEU A CD2 1 ATOM 5007 N N . THR A 1 635 ? 63.122 80.772 -33.747 1.00 14.52 ? 635 THR A N 1 ATOM 5008 C CA . THR A 1 635 ? 64.040 81.784 -34.224 1.00 14.28 ? 635 THR A CA 1 ATOM 5009 C C . THR A 1 635 ? 63.264 82.945 -34.844 1.00 15.29 ? 635 THR A C 1 ATOM 5010 O O . THR A 1 635 ? 62.312 82.734 -35.596 1.00 14.31 ? 635 THR A O 1 ATOM 5011 C CB . THR A 1 635 ? 64.976 81.170 -35.309 1.00 13.92 ? 635 THR A CB 1 ATOM 5012 O OG1 . THR A 1 635 ? 65.641 80.017 -34.767 1.00 13.59 ? 635 THR A OG1 1 ATOM 5013 C CG2 . THR A 1 635 ? 66.009 82.201 -35.793 1.00 10.46 ? 635 THR A CG2 1 ATOM 5014 N N . ILE A 1 636 ? 63.668 84.176 -34.537 1.00 17.17 ? 636 ILE A N 1 ATOM 5015 C CA . ILE A 1 636 ? 62.972 85.329 -35.103 1.00 17.80 ? 636 ILE A CA 1 ATOM 5016 C C . ILE A 1 636 ? 63.532 85.628 -36.495 1.00 19.17 ? 636 ILE A C 1 ATOM 5017 O O . ILE A 1 636 ? 64.682 85.321 -36.793 1.00 18.31 ? 636 ILE A O 1 ATOM 5018 C CB . ILE A 1 636 ? 63.092 86.592 -34.179 1.00 18.19 ? 636 ILE A CB 1 ATOM 5019 C CG1 . ILE A 1 636 ? 62.178 87.717 -34.693 1.00 18.89 ? 636 ILE A CG1 1 ATOM 5020 C CG2 . ILE A 1 636 ? 64.528 87.076 -34.134 1.00 17.78 ? 636 ILE A CG2 1 ATOM 5021 C CD1 . ILE A 1 636 ? 62.257 89.011 -33.875 1.00 18.87 ? 636 ILE A CD1 1 ATOM 5022 N N . SER A 1 637 ? 62.693 86.202 -37.351 1.00 20.62 ? 637 SER A N 1 ATOM 5023 C CA . SER A 1 637 ? 63.081 86.538 -38.698 1.00 23.77 ? 637 SER A CA 1 ATOM 5024 C C . SER A 1 637 ? 62.616 87.976 -38.915 1.00 25.20 ? 637 SER A C 1 ATOM 5025 O O . SER A 1 637 ? 61.784 88.471 -38.175 1.00 24.64 ? 637 SER A O 1 ATOM 5026 C CB . SER A 1 637 ? 62.396 85.569 -39.666 1.00 24.91 ? 637 SER A CB 1 ATOM 5027 O OG . SER A 1 637 ? 62.761 85.842 -40.986 1.00 29.36 ? 637 SER A OG 1 ATOM 5028 N N . ASP A 1 638 ? 63.155 88.671 -39.908 1.00 27.89 ? 638 ASP A N 1 ATOM 5029 C CA . ASP A 1 638 ? 62.718 90.050 -40.089 1.00 30.74 ? 638 ASP A CA 1 ATOM 5030 C C . ASP A 1 638 ? 61.392 90.101 -40.854 1.00 31.54 ? 638 ASP A C 1 ATOM 5031 O O . ASP A 1 638 ? 60.746 91.144 -40.894 1.00 32.56 ? 638 ASP A O 1 ATOM 5032 C CB . ASP A 1 638 ? 63.793 90.877 -40.804 1.00 33.65 ? 638 ASP A CB 1 ATOM 5033 C CG . ASP A 1 638 ? 63.735 90.717 -42.299 1.00 37.51 ? 638 ASP A CG 1 ATOM 5034 O OD1 . ASP A 1 638 ? 63.944 89.577 -42.793 1.00 39.92 ? 638 ASP A OD1 1 ATOM 5035 O OD2 . ASP A 1 638 ? 63.460 91.733 -42.988 1.00 40.39 ? 638 ASP A OD2 1 ATOM 5036 N N . SER A 1 639 ? 60.975 88.968 -41.430 1.00 31.35 ? 639 SER A N 1 ATOM 5037 C CA . SER A 1 639 ? 59.721 88.908 -42.183 1.00 31.14 ? 639 SER A CA 1 ATOM 5038 C C . SER A 1 639 ? 59.144 87.500 -42.180 1.00 30.06 ? 639 SER A C 1 ATOM 5039 O O . SER A 1 639 ? 59.798 86.561 -41.739 1.00 29.62 ? 639 SER A O 1 ATOM 5040 C CB . SER A 1 639 ? 59.954 89.322 -43.631 1.00 32.43 ? 639 SER A CB 1 ATOM 5041 O OG . SER A 1 639 ? 60.659 88.303 -44.317 1.00 34.27 ? 639 SER A OG 1 ATOM 5042 N N . LYS A 1 640 ? 57.929 87.358 -42.700 1.00 29.53 ? 640 LYS A N 1 ATOM 5043 C CA . LYS A 1 640 ? 57.257 86.064 -42.743 1.00 29.10 ? 640 LYS A CA 1 ATOM 5044 C C . LYS A 1 640 ? 58.168 84.899 -43.135 1.00 27.58 ? 640 LYS A C 1 ATOM 5045 O O . LYS A 1 640 ? 58.661 84.833 -44.258 1.00 27.95 ? 640 LYS A O 1 ATOM 5046 C CB . LYS A 1 640 ? 56.052 86.107 -43.688 1.00 30.25 ? 640 LYS A CB 1 ATOM 5047 C CG . LYS A 1 640 ? 54.987 87.124 -43.292 1.00 33.18 ? 640 LYS A CG 1 ATOM 5048 C CD . LYS A 1 640 ? 53.540 86.652 -43.592 1.00 34.92 ? 640 LYS A CD 1 ATOM 5049 C CE . LYS A 1 640 ? 53.226 86.593 -45.064 1.00 35.47 ? 640 LYS A CE 1 ATOM 5050 N NZ . LYS A 1 640 ? 53.332 87.934 -45.705 1.00 36.75 ? 640 LYS A NZ 1 ATOM 5051 N N . PRO A 1 641 ? 58.415 83.964 -42.200 1.00 26.27 ? 641 PRO A N 1 ATOM 5052 C CA . PRO A 1 641 ? 59.273 82.829 -42.534 1.00 24.61 ? 641 PRO A CA 1 ATOM 5053 C C . PRO A 1 641 ? 58.535 81.804 -43.391 1.00 23.69 ? 641 PRO A C 1 ATOM 5054 O O . PRO A 1 641 ? 57.318 81.697 -43.359 1.00 22.63 ? 641 PRO A O 1 ATOM 5055 C CB . PRO A 1 641 ? 59.684 82.284 -41.161 1.00 25.88 ? 641 PRO A CB 1 ATOM 5056 C CG . PRO A 1 641 ? 58.560 82.621 -40.303 1.00 26.08 ? 641 PRO A CG 1 ATOM 5057 C CD . PRO A 1 641 ? 58.133 84.003 -40.755 1.00 25.67 ? 641 PRO A CD 1 ATOM 5058 N N . GLU A 1 642 ? 59.294 81.043 -44.153 1.00 23.09 ? 642 GLU A N 1 ATOM 5059 C CA . GLU A 1 642 ? 58.749 80.046 -45.050 1.00 23.23 ? 642 GLU A CA 1 ATOM 5060 C C . GLU A 1 642 ? 57.849 78.959 -44.456 1.00 21.94 ? 642 GLU A C 1 ATOM 5061 O O . GLU A 1 642 ? 56.876 78.531 -45.094 1.00 20.83 ? 642 GLU A O 1 ATOM 5062 C CB . GLU A 1 642 ? 59.921 79.397 -45.808 1.00 25.52 ? 642 GLU A CB 1 ATOM 5063 C CG . GLU A 1 642 ? 59.554 78.231 -46.701 1.00 30.35 ? 642 GLU A CG 1 ATOM 5064 C CD . GLU A 1 642 ? 60.774 77.626 -47.424 1.00 33.83 ? 642 GLU A CD 1 ATOM 5065 O OE1 . GLU A 1 642 ? 60.651 76.468 -47.909 1.00 36.58 ? 642 GLU A OE1 1 ATOM 5066 O OE2 . GLU A 1 642 ? 61.843 78.297 -47.507 1.00 34.31 ? 642 GLU A OE2 1 ATOM 5067 N N . HIS A 1 643 ? 58.148 78.500 -43.245 1.00 19.10 ? 643 HIS A N 1 ATOM 5068 C CA . HIS A 1 643 ? 57.354 77.400 -42.665 1.00 17.86 ? 643 HIS A CA 1 ATOM 5069 C C . HIS A 1 643 ? 56.349 77.798 -41.600 1.00 16.52 ? 643 HIS A C 1 ATOM 5070 O O . HIS A 1 643 ? 55.871 76.953 -40.841 1.00 14.85 ? 643 HIS A O 1 ATOM 5071 C CB . HIS A 1 643 ? 58.317 76.342 -42.108 1.00 18.11 ? 643 HIS A CB 1 ATOM 5072 C CG . HIS A 1 643 ? 59.165 75.724 -43.171 1.00 19.77 ? 643 HIS A CG 1 ATOM 5073 N ND1 . HIS A 1 643 ? 58.692 74.736 -44.007 1.00 21.63 ? 643 HIS A ND1 1 ATOM 5074 C CD2 . HIS A 1 643 ? 60.393 76.057 -43.639 1.00 19.75 ? 643 HIS A CD2 1 ATOM 5075 C CE1 . HIS A 1 643 ? 59.588 74.491 -44.951 1.00 20.42 ? 643 HIS A CE1 1 ATOM 5076 N NE2 . HIS A 1 643 ? 60.628 75.282 -44.749 1.00 21.72 ? 643 HIS A NE2 1 ATOM 5077 N N . THR A 1 644 ? 56.050 79.086 -41.543 1.00 15.66 ? 644 THR A N 1 ATOM 5078 C CA . THR A 1 644 ? 55.093 79.599 -40.582 1.00 16.01 ? 644 THR A CA 1 ATOM 5079 C C . THR A 1 644 ? 53.940 80.231 -41.365 1.00 16.31 ? 644 THR A C 1 ATOM 5080 O O . THR A 1 644 ? 54.188 80.981 -42.314 1.00 14.72 ? 644 THR A O 1 ATOM 5081 C CB . THR A 1 644 ? 55.746 80.659 -39.688 1.00 17.01 ? 644 THR A CB 1 ATOM 5082 O OG1 . THR A 1 644 ? 56.821 80.044 -38.959 1.00 17.11 ? 644 THR A OG1 1 ATOM 5083 C CG2 . THR A 1 644 ? 54.710 81.265 -38.674 1.00 17.14 ? 644 THR A CG2 1 ATOM 5084 N N . SER A 1 645 ? 52.704 79.872 -41.010 1.00 14.61 ? 645 SER A N 1 ATOM 5085 C CA . SER A 1 645 ? 51.521 80.441 -41.641 1.00 15.38 ? 645 SER A CA 1 ATOM 5086 C C . SER A 1 645 ? 50.827 81.289 -40.567 1.00 15.06 ? 645 SER A C 1 ATOM 5087 O O . SER A 1 645 ? 51.162 81.223 -39.371 1.00 14.02 ? 645 SER A O 1 ATOM 5088 C CB . SER A 1 645 ? 50.583 79.351 -42.188 1.00 16.36 ? 645 SER A CB 1 ATOM 5089 O OG . SER A 1 645 ? 50.041 78.554 -41.146 1.00 15.37 ? 645 SER A OG 1 ATOM 5090 N N . TYR A 1 646 ? 49.889 82.118 -41.010 1.00 14.18 ? 646 TYR A N 1 ATOM 5091 C CA . TYR A 1 646 ? 49.169 83.021 -40.128 1.00 13.89 ? 646 TYR A CA 1 ATOM 5092 C C . TYR A 1 646 ? 47.674 82.799 -40.253 1.00 13.61 ? 646 TYR A C 1 ATOM 5093 O O . TYR A 1 646 ? 47.146 82.706 -41.359 1.00 13.47 ? 646 TYR A O 1 ATOM 5094 C CB . TYR A 1 646 ? 49.527 84.489 -40.453 1.00 13.87 ? 646 TYR A CB 1 ATOM 5095 C CG . TYR A 1 646 ? 50.993 84.763 -40.241 1.00 14.12 ? 646 TYR A CG 1 ATOM 5096 C CD1 . TYR A 1 646 ? 51.921 84.462 -41.243 1.00 14.73 ? 646 TYR A CD1 1 ATOM 5097 C CD2 . TYR A 1 646 ? 51.472 85.135 -38.995 1.00 13.09 ? 646 TYR A CD2 1 ATOM 5098 C CE1 . TYR A 1 646 ? 53.274 84.511 -40.997 1.00 14.80 ? 646 TYR A CE1 1 ATOM 5099 C CE2 . TYR A 1 646 ? 52.824 85.181 -38.734 1.00 13.00 ? 646 TYR A CE2 1 ATOM 5100 C CZ . TYR A 1 646 ? 53.718 84.860 -39.742 1.00 14.59 ? 646 TYR A CZ 1 ATOM 5101 O OH . TYR A 1 646 ? 55.061 84.843 -39.496 1.00 16.15 ? 646 TYR A OH 1 ATOM 5102 N N . ALA A 1 647 ? 46.998 82.701 -39.112 1.00 12.53 ? 647 ALA A N 1 ATOM 5103 C CA . ALA A 1 647 ? 45.568 82.477 -39.114 1.00 11.97 ? 647 ALA A CA 1 ATOM 5104 C C . ALA A 1 647 ? 44.750 83.721 -39.491 1.00 12.15 ? 647 ALA A C 1 ATOM 5105 O O . ALA A 1 647 ? 45.159 84.863 -39.266 1.00 11.48 ? 647 ALA A O 1 ATOM 5106 C CB . ALA A 1 647 ? 45.129 81.966 -37.741 1.00 13.58 ? 647 ALA A CB 1 ATOM 5107 N N . SER A 1 648 ? 43.601 83.506 -40.105 1.00 12.47 ? 648 SER A N 1 ATOM 5108 C CA . SER A 1 648 ? 42.730 84.642 -40.424 1.00 12.57 ? 648 SER A CA 1 ATOM 5109 C C . SER A 1 648 ? 41.871 84.784 -39.171 1.00 12.46 ? 648 SER A C 1 ATOM 5110 O O . SER A 1 648 ? 41.747 83.814 -38.385 1.00 12.98 ? 648 SER A O 1 ATOM 5111 C CB . SER A 1 648 ? 41.840 84.296 -41.616 1.00 13.33 ? 648 SER A CB 1 ATOM 5112 O OG . SER A 1 648 ? 41.060 83.170 -41.262 1.00 16.78 ? 648 SER A OG 1 ATOM 5113 N N . ASN A 1 649 ? 41.299 85.966 -38.947 1.00 11.53 ? 649 ASN A N 1 ATOM 5114 C CA . ASN A 1 649 ? 40.434 86.179 -37.784 1.00 12.26 ? 649 ASN A CA 1 ATOM 5115 C C . ASN A 1 649 ? 39.207 86.919 -38.232 1.00 13.25 ? 649 ASN A C 1 ATOM 5116 O O . ASN A 1 649 ? 39.307 87.928 -38.962 1.00 12.43 ? 649 ASN A O 1 ATOM 5117 C CB . ASN A 1 649 ? 41.130 86.999 -36.697 1.00 11.47 ? 649 ASN A CB 1 ATOM 5118 C CG . ASN A 1 649 ? 42.319 86.276 -36.094 1.00 13.15 ? 649 ASN A CG 1 ATOM 5119 O OD1 . ASN A 1 649 ? 42.185 85.507 -35.121 1.00 12.26 ? 649 ASN A OD1 1 ATOM 5120 N ND2 . ASN A 1 649 ? 43.488 86.485 -36.690 1.00 11.23 ? 649 ASN A ND2 1 ATOM 5121 N N . LEU A 1 650 ? 38.057 86.461 -37.749 1.00 12.73 ? 650 LEU A N 1 ATOM 5122 C CA . LEU A 1 650 ? 36.772 87.072 -38.112 1.00 13.98 ? 650 LEU A CA 1 ATOM 5123 C C . LEU A 1 650 ? 35.955 87.340 -36.876 1.00 14.36 ? 650 LEU A C 1 ATOM 5124 O O . LEU A 1 650 ? 35.586 86.403 -36.154 1.00 13.85 ? 650 LEU A O 1 ATOM 5125 C CB . LEU A 1 650 ? 35.971 86.132 -39.013 1.00 12.81 ? 650 LEU A CB 1 ATOM 5126 C CG . LEU A 1 650 ? 34.542 86.516 -39.401 1.00 13.81 ? 650 LEU A CG 1 ATOM 5127 C CD1 . LEU A 1 650 ? 34.530 87.823 -40.267 1.00 13.26 ? 650 LEU A CD1 1 ATOM 5128 C CD2 . LEU A 1 650 ? 33.956 85.333 -40.210 1.00 12.95 ? 650 LEU A CD2 1 ATOM 5129 N N . LEU A 1 651 ? 35.644 88.611 -36.654 1.00 14.85 ? 651 LEU A N 1 ATOM 5130 C CA . LEU A 1 651 ? 34.857 89.021 -35.503 1.00 15.41 ? 651 LEU A CA 1 ATOM 5131 C C . LEU A 1 651 ? 33.412 89.309 -35.943 1.00 16.34 ? 651 LEU A C 1 ATOM 5132 O O . LEU A 1 651 ? 33.141 90.227 -36.735 1.00 17.28 ? 651 LEU A O 1 ATOM 5133 C CB . LEU A 1 651 ? 35.529 90.232 -34.865 1.00 17.98 ? 651 LEU A CB 1 ATOM 5134 C CG . LEU A 1 651 ? 35.216 90.716 -33.438 1.00 20.41 ? 651 LEU A CG 1 ATOM 5135 C CD1 . LEU A 1 651 ? 34.066 91.693 -33.430 1.00 22.64 ? 651 LEU A CD1 1 ATOM 5136 C CD2 . LEU A 1 651 ? 34.915 89.510 -32.565 1.00 20.40 ? 651 LEU A CD2 1 ATOM 5137 N N . LEU A 1 652 ? 32.480 88.505 -35.441 1.00 15.39 ? 652 LEU A N 1 ATOM 5138 C CA . LEU A 1 652 ? 31.083 88.637 -35.804 1.00 15.41 ? 652 LEU A CA 1 ATOM 5139 C C . LEU A 1 652 ? 30.244 89.285 -34.712 1.00 17.49 ? 652 LEU A C 1 ATOM 5140 O O . LEU A 1 652 ? 30.055 88.747 -33.612 1.00 15.34 ? 652 LEU A O 1 ATOM 5141 C CB . LEU A 1 652 ? 30.511 87.266 -36.170 1.00 15.18 ? 652 LEU A CB 1 ATOM 5142 C CG . LEU A 1 652 ? 31.249 86.520 -37.295 1.00 13.81 ? 652 LEU A CG 1 ATOM 5143 C CD1 . LEU A 1 652 ? 30.688 85.106 -37.392 1.00 15.18 ? 652 LEU A CD1 1 ATOM 5144 C CD2 . LEU A 1 652 ? 31.082 87.242 -38.649 1.00 13.21 ? 652 LEU A CD2 1 ATOM 5145 N N . ARG A 1 653 ? 29.761 90.473 -35.039 1.00 18.16 ? 653 ARG A N 1 ATOM 5146 C CA . ARG A 1 653 ? 28.939 91.247 -34.145 1.00 21.33 ? 653 ARG A CA 1 ATOM 5147 C C . ARG A 1 653 ? 28.419 92.454 -34.919 1.00 22.92 ? 653 ARG A C 1 ATOM 5148 O O . ARG A 1 653 ? 28.977 92.839 -35.957 1.00 22.20 ? 653 ARG A O 1 ATOM 5149 C CB . ARG A 1 653 ? 29.757 91.713 -32.965 1.00 21.44 ? 653 ARG A CB 1 ATOM 5150 C CG . ARG A 1 653 ? 30.861 92.641 -33.329 1.00 23.95 ? 653 ARG A CG 1 ATOM 5151 C CD . ARG A 1 653 ? 30.689 93.872 -32.492 1.00 27.24 ? 653 ARG A CD 1 ATOM 5152 N NE . ARG A 1 653 ? 31.502 93.853 -31.290 1.00 28.37 ? 653 ARG A NE 1 ATOM 5153 C CZ . ARG A 1 653 ? 31.176 94.459 -30.152 1.00 29.73 ? 653 ARG A CZ 1 ATOM 5154 N NH1 . ARG A 1 653 ? 30.038 95.120 -30.041 1.00 31.41 ? 653 ARG A NH1 1 ATOM 5155 N NH2 . ARG A 1 653 ? 32.014 94.445 -29.134 1.00 31.38 ? 653 ARG A NH2 1 ATOM 5156 N N . LYS A 1 654 ? 27.344 93.030 -34.414 1.00 25.11 ? 654 LYS A N 1 ATOM 5157 C CA . LYS A 1 654 ? 26.758 94.215 -35.022 1.00 27.51 ? 654 LYS A CA 1 ATOM 5158 C C . LYS A 1 654 ? 27.593 95.361 -34.445 1.00 27.70 ? 654 LYS A C 1 ATOM 5159 O O . LYS A 1 654 ? 28.202 95.204 -33.401 1.00 28.22 ? 654 LYS A O 1 ATOM 5160 C CB . LYS A 1 654 ? 25.301 94.339 -34.570 1.00 28.51 ? 654 LYS A CB 1 ATOM 5161 C CG . LYS A 1 654 ? 24.447 93.155 -34.995 1.00 31.06 ? 654 LYS A CG 1 ATOM 5162 C CD . LYS A 1 654 ? 23.430 93.546 -36.061 1.00 33.14 ? 654 LYS A CD 1 ATOM 5163 C CE . LYS A 1 654 ? 24.082 94.219 -37.265 1.00 34.74 ? 654 LYS A CE 1 ATOM 5164 N NZ . LYS A 1 654 ? 23.050 94.636 -38.302 1.00 37.16 ? 654 LYS A NZ 1 ATOM 5165 N N . ASN A 1 655 ? 27.665 96.489 -35.121 1.00 28.27 ? 655 ASN A N 1 ATOM 5166 C CA . ASN A 1 655 ? 28.417 97.589 -34.540 1.00 29.26 ? 655 ASN A CA 1 ATOM 5167 C C . ASN A 1 655 ? 29.854 97.219 -34.158 1.00 28.73 ? 655 ASN A C 1 ATOM 5168 O O . ASN A 1 655 ? 30.242 97.315 -32.995 1.00 28.31 ? 655 ASN A O 1 ATOM 5169 C CB . ASN A 1 655 ? 27.694 98.081 -33.285 1.00 31.63 ? 655 ASN A CB 1 ATOM 5170 C CG . ASN A 1 655 ? 28.220 99.416 -32.811 1.00 35.22 ? 655 ASN A CG 1 ATOM 5171 O OD1 . ASN A 1 655 ? 28.473 100.319 -33.630 1.00 36.63 ? 655 ASN A OD1 1 ATOM 5172 N ND2 . ASN A 1 655 ? 28.374 99.569 -31.492 1.00 35.25 ? 655 ASN A ND2 1 ATOM 5173 N N . PRO A 1 656 ? 30.669 96.791 -35.128 1.00 27.66 ? 656 PRO A N 1 ATOM 5174 C CA . PRO A 1 656 ? 32.032 96.449 -34.724 1.00 27.16 ? 656 PRO A CA 1 ATOM 5175 C C . PRO A 1 656 ? 32.926 97.673 -34.733 1.00 26.21 ? 656 PRO A C 1 ATOM 5176 O O . PRO A 1 656 ? 32.574 98.691 -35.314 1.00 26.46 ? 656 PRO A O 1 ATOM 5177 C CB . PRO A 1 656 ? 32.461 95.468 -35.808 1.00 27.29 ? 656 PRO A CB 1 ATOM 5178 C CG . PRO A 1 656 ? 31.818 96.087 -37.026 1.00 26.72 ? 656 PRO A CG 1 ATOM 5179 C CD . PRO A 1 656 ? 30.415 96.358 -36.514 1.00 27.50 ? 656 PRO A CD 1 ATOM 5180 N N . THR A 1 657 ? 34.078 97.550 -34.081 1.00 25.33 ? 657 THR A N 1 ATOM 5181 C CA . THR A 1 657 ? 35.094 98.593 -34.058 1.00 24.09 ? 657 THR A CA 1 ATOM 5182 C C . THR A 1 657 ? 36.409 97.904 -34.437 1.00 23.81 ? 657 THR A C 1 ATOM 5183 O O . THR A 1 657 ? 36.534 96.685 -34.304 1.00 24.11 ? 657 THR A O 1 ATOM 5184 C CB . THR A 1 657 ? 35.220 99.236 -32.668 1.00 24.46 ? 657 THR A CB 1 ATOM 5185 O OG1 . THR A 1 657 ? 35.283 98.216 -31.666 1.00 25.35 ? 657 THR A OG1 1 ATOM 5186 C CG2 . THR A 1 657 ? 34.018 100.133 -32.395 1.00 23.43 ? 657 THR A CG2 1 ATOM 5187 N N . SER A 1 658 ? 37.374 98.676 -34.911 1.00 22.00 ? 658 SER A N 1 ATOM 5188 C CA . SER A 1 658 ? 38.666 98.150 -35.329 1.00 22.28 ? 658 SER A CA 1 ATOM 5189 C C . SER A 1 658 ? 39.386 97.327 -34.241 1.00 22.35 ? 658 SER A C 1 ATOM 5190 O O . SER A 1 658 ? 39.180 97.538 -33.034 1.00 20.41 ? 658 SER A O 1 ATOM 5191 C CB . SER A 1 658 ? 39.559 99.310 -35.782 1.00 22.68 ? 658 SER A CB 1 ATOM 5192 O OG . SER A 1 658 ? 39.787 100.190 -34.693 1.00 25.40 ? 658 SER A OG 1 ATOM 5193 N N . LEU A 1 659 ? 40.221 96.389 -34.695 1.00 22.05 ? 659 LEU A N 1 ATOM 5194 C CA . LEU A 1 659 ? 40.999 95.505 -33.825 1.00 22.58 ? 659 LEU A CA 1 ATOM 5195 C C . LEU A 1 659 ? 42.373 95.381 -34.453 1.00 22.88 ? 659 LEU A C 1 ATOM 5196 O O . LEU A 1 659 ? 42.638 94.476 -35.248 1.00 23.58 ? 659 LEU A O 1 ATOM 5197 C CB . LEU A 1 659 ? 40.351 94.120 -33.721 1.00 22.77 ? 659 LEU A CB 1 ATOM 5198 C CG . LEU A 1 659 ? 39.072 94.014 -32.880 1.00 23.73 ? 659 LEU A CG 1 ATOM 5199 C CD1 . LEU A 1 659 ? 38.410 92.657 -33.102 1.00 25.13 ? 659 LEU A CD1 1 ATOM 5200 C CD2 . LEU A 1 659 ? 39.391 94.202 -31.429 1.00 23.16 ? 659 LEU A CD2 1 ATOM 5201 N N . PRO A 1 660 ? 43.255 96.336 -34.154 1.00 23.26 ? 660 PRO A N 1 ATOM 5202 C CA . PRO A 1 660 ? 44.615 96.318 -34.703 1.00 23.00 ? 660 PRO A CA 1 ATOM 5203 C C . PRO A 1 660 ? 45.452 95.211 -34.029 1.00 22.04 ? 660 PRO A C 1 ATOM 5204 O O . PRO A 1 660 ? 45.219 94.865 -32.883 1.00 21.52 ? 660 PRO A O 1 ATOM 5205 C CB . PRO A 1 660 ? 45.124 97.730 -34.394 1.00 23.04 ? 660 PRO A CB 1 ATOM 5206 C CG . PRO A 1 660 ? 44.425 98.057 -33.109 1.00 22.90 ? 660 PRO A CG 1 ATOM 5207 C CD . PRO A 1 660 ? 43.006 97.572 -33.390 1.00 23.40 ? 660 PRO A CD 1 ATOM 5208 N N . LEU A 1 661 ? 46.430 94.664 -34.737 1.00 22.76 ? 661 LEU A N 1 ATOM 5209 C CA . LEU A 1 661 ? 47.225 93.579 -34.151 1.00 21.35 ? 661 LEU A CA 1 ATOM 5210 C C . LEU A 1 661 ? 48.748 93.766 -34.307 1.00 21.04 ? 661 LEU A C 1 ATOM 5211 O O . LEU A 1 661 ? 49.486 92.811 -34.549 1.00 20.79 ? 661 LEU A O 1 ATOM 5212 C CB . LEU A 1 661 ? 46.776 92.257 -34.789 1.00 20.71 ? 661 LEU A CB 1 ATOM 5213 C CG . LEU A 1 661 ? 45.318 91.836 -34.563 1.00 19.70 ? 661 LEU A CG 1 ATOM 5214 C CD1 . LEU A 1 661 ? 45.021 90.526 -35.311 1.00 18.40 ? 661 LEU A CD1 1 ATOM 5215 C CD2 . LEU A 1 661 ? 45.097 91.657 -33.082 1.00 19.61 ? 661 LEU A CD2 1 ATOM 5216 N N . GLY A 1 662 ? 49.213 95.003 -34.175 1.00 21.18 ? 662 GLY A N 1 ATOM 5217 C CA . GLY A 1 662 ? 50.633 95.263 -34.308 1.00 20.91 ? 662 GLY A CA 1 ATOM 5218 C C . GLY A 1 662 ? 51.208 94.680 -35.578 1.00 21.31 ? 662 GLY A C 1 ATOM 5219 O O . GLY A 1 662 ? 50.666 94.895 -36.663 1.00 20.68 ? 662 GLY A O 1 ATOM 5220 N N . GLN A 1 663 ? 52.280 93.904 -35.463 1.00 22.17 ? 663 GLN A N 1 ATOM 5221 C CA . GLN A 1 663 ? 52.883 93.355 -36.663 1.00 23.52 ? 663 GLN A CA 1 ATOM 5222 C C . GLN A 1 663 ? 52.161 92.183 -37.292 1.00 22.68 ? 663 GLN A C 1 ATOM 5223 O O . GLN A 1 663 ? 52.536 91.757 -38.375 1.00 23.03 ? 663 GLN A O 1 ATOM 5224 C CB . GLN A 1 663 ? 54.316 92.917 -36.419 1.00 26.35 ? 663 GLN A CB 1 ATOM 5225 C CG . GLN A 1 663 ? 55.213 93.905 -35.701 1.00 29.24 ? 663 GLN A CG 1 ATOM 5226 C CD . GLN A 1 663 ? 56.472 93.177 -35.219 1.00 30.27 ? 663 GLN A CD 1 ATOM 5227 O OE1 . GLN A 1 663 ? 57.370 92.894 -36.026 1.00 29.37 ? 663 GLN A OE1 1 ATOM 5228 N NE2 . GLN A 1 663 ? 56.513 92.822 -33.914 1.00 29.99 ? 663 GLN A NE2 1 ATOM 5229 N N . TYR A 1 664 ? 51.140 91.654 -36.638 1.00 22.36 ? 664 TYR A N 1 ATOM 5230 C CA . TYR A 1 664 ? 50.427 90.528 -37.221 1.00 21.89 ? 664 TYR A CA 1 ATOM 5231 C C . TYR A 1 664 ? 50.133 90.838 -38.691 1.00 22.48 ? 664 TYR A C 1 ATOM 5232 O O . TYR A 1 664 ? 49.520 91.843 -39.002 1.00 21.97 ? 664 TYR A O 1 ATOM 5233 C CB . TYR A 1 664 ? 49.140 90.290 -36.450 1.00 20.52 ? 664 TYR A CB 1 ATOM 5234 C CG . TYR A 1 664 ? 48.557 88.937 -36.719 1.00 18.52 ? 664 TYR A CG 1 ATOM 5235 C CD1 . TYR A 1 664 ? 49.111 87.803 -36.130 1.00 16.87 ? 664 TYR A CD1 1 ATOM 5236 C CD2 . TYR A 1 664 ? 47.421 88.788 -37.528 1.00 17.27 ? 664 TYR A CD2 1 ATOM 5237 C CE1 . TYR A 1 664 ? 48.542 86.552 -36.319 1.00 15.86 ? 664 TYR A CE1 1 ATOM 5238 C CE2 . TYR A 1 664 ? 46.844 87.535 -37.738 1.00 15.58 ? 664 TYR A CE2 1 ATOM 5239 C CZ . TYR A 1 664 ? 47.413 86.419 -37.118 1.00 15.49 ? 664 TYR A CZ 1 ATOM 5240 O OH . TYR A 1 664 ? 46.863 85.178 -37.264 1.00 13.22 ? 664 TYR A OH 1 ATOM 5241 N N . PRO A 1 665 ? 50.568 89.967 -39.612 1.00 23.94 ? 665 PRO A N 1 ATOM 5242 C CA . PRO A 1 665 ? 50.381 90.141 -41.064 1.00 25.31 ? 665 PRO A CA 1 ATOM 5243 C C . PRO A 1 665 ? 48.984 90.044 -41.694 1.00 25.90 ? 665 PRO A C 1 ATOM 5244 O O . PRO A 1 665 ? 48.808 90.377 -42.865 1.00 27.23 ? 665 PRO A O 1 ATOM 5245 C CB . PRO A 1 665 ? 51.327 89.096 -41.653 1.00 25.16 ? 665 PRO A CB 1 ATOM 5246 C CG . PRO A 1 665 ? 51.199 87.988 -40.675 1.00 26.51 ? 665 PRO A CG 1 ATOM 5247 C CD . PRO A 1 665 ? 51.233 88.682 -39.323 1.00 24.18 ? 665 PRO A CD 1 ATOM 5248 N N . GLU A 1 666 ? 47.991 89.599 -40.937 1.00 25.82 ? 666 GLU A N 1 ATOM 5249 C CA . GLU A 1 666 ? 46.660 89.445 -41.498 1.00 25.20 ? 666 GLU A CA 1 ATOM 5250 C C . GLU A 1 666 ? 45.676 90.336 -40.758 1.00 23.09 ? 666 GLU A C 1 ATOM 5251 O O . GLU A 1 666 ? 45.560 90.250 -39.540 1.00 21.68 ? 666 GLU A O 1 ATOM 5252 C CB . GLU A 1 666 ? 46.242 87.980 -41.380 1.00 28.09 ? 666 GLU A CB 1 ATOM 5253 C CG . GLU A 1 666 ? 44.838 87.714 -41.845 1.00 32.61 ? 666 GLU A CG 1 ATOM 5254 C CD . GLU A 1 666 ? 44.791 87.206 -43.276 1.00 35.88 ? 666 GLU A CD 1 ATOM 5255 O OE1 . GLU A 1 666 ? 45.824 87.360 -44.009 1.00 35.05 ? 666 GLU A OE1 1 ATOM 5256 O OE2 . GLU A 1 666 ? 43.708 86.663 -43.641 1.00 37.25 ? 666 GLU A OE2 1 ATOM 5257 N N . ASP A 1 667 ? 44.972 91.185 -41.507 1.00 21.04 ? 667 ASP A N 1 ATOM 5258 C CA . ASP A 1 667 ? 43.993 92.116 -40.926 1.00 21.17 ? 667 ASP A CA 1 ATOM 5259 C C . ASP A 1 667 ? 42.734 91.383 -40.477 1.00 17.88 ? 667 ASP A C 1 ATOM 5260 O O . ASP A 1 667 ? 42.219 90.548 -41.201 1.00 16.81 ? 667 ASP A O 1 ATOM 5261 C CB . ASP A 1 667 ? 43.569 93.184 -41.961 1.00 23.10 ? 667 ASP A CB 1 ATOM 5262 C CG . ASP A 1 667 ? 44.721 94.060 -42.395 1.00 27.55 ? 667 ASP A CG 1 ATOM 5263 O OD1 . ASP A 1 667 ? 45.376 94.659 -41.506 1.00 29.63 ? 667 ASP A OD1 1 ATOM 5264 O OD2 . ASP A 1 667 ? 44.972 94.139 -43.618 1.00 29.46 ? 667 ASP A OD2 1 ATOM 5265 N N . VAL A 1 668 ? 42.241 91.715 -39.304 1.00 15.99 ? 668 VAL A N 1 ATOM 5266 C CA . VAL A 1 668 ? 41.025 91.113 -38.806 1.00 14.73 ? 668 VAL A CA 1 ATOM 5267 C C . VAL A 1 668 ? 39.868 91.539 -39.713 1.00 15.67 ? 668 VAL A C 1 ATOM 5268 O O . VAL A 1 668 ? 39.823 92.697 -40.155 1.00 14.26 ? 668 VAL A O 1 ATOM 5269 C CB . VAL A 1 668 ? 40.732 91.598 -37.380 1.00 15.60 ? 668 VAL A CB 1 ATOM 5270 C CG1 . VAL A 1 668 ? 39.372 91.050 -36.906 1.00 14.63 ? 668 VAL A CG1 1 ATOM 5271 C CG2 . VAL A 1 668 ? 41.883 91.160 -36.434 1.00 14.18 ? 668 VAL A CG2 1 ATOM 5272 N N . LYS A 1 669 ? 38.954 90.602 -39.981 1.00 14.17 ? 669 LYS A N 1 ATOM 5273 C CA . LYS A 1 669 ? 37.774 90.830 -40.806 1.00 15.27 ? 669 LYS A CA 1 ATOM 5274 C C . LYS A 1 669 ? 36.546 90.918 -39.882 1.00 14.58 ? 669 LYS A C 1 ATOM 5275 O O . LYS A 1 669 ? 36.559 90.349 -38.786 1.00 13.98 ? 669 LYS A O 1 ATOM 5276 C CB . LYS A 1 669 ? 37.613 89.675 -41.784 1.00 18.36 ? 669 LYS A CB 1 ATOM 5277 C CG . LYS A 1 669 ? 38.064 89.975 -43.226 1.00 24.63 ? 669 LYS A CG 1 ATOM 5278 C CD . LYS A 1 669 ? 39.514 90.500 -43.288 1.00 28.94 ? 669 LYS A CD 1 ATOM 5279 C CE . LYS A 1 669 ? 39.919 90.967 -44.701 1.00 30.40 ? 669 LYS A CE 1 ATOM 5280 N NZ . LYS A 1 669 ? 39.476 89.970 -45.754 1.00 30.89 ? 669 LYS A NZ 1 ATOM 5281 N N . PHE A 1 670 ? 35.497 91.620 -40.312 1.00 13.04 ? 670 PHE A N 1 ATOM 5282 C CA . PHE A 1 670 ? 34.273 91.763 -39.506 1.00 13.93 ? 670 PHE A CA 1 ATOM 5283 C C . PHE A 1 670 ? 33.002 91.344 -40.255 1.00 14.13 ? 670 PHE A C 1 ATOM 5284 O O . PHE A 1 670 ? 33.010 91.211 -41.478 1.00 13.34 ? 670 PHE A O 1 ATOM 5285 C CB . PHE A 1 670 ? 34.107 93.224 -39.024 1.00 13.45 ? 670 PHE A CB 1 ATOM 5286 C CG . PHE A 1 670 ? 35.258 93.724 -38.220 1.00 13.78 ? 670 PHE A CG 1 ATOM 5287 C CD1 . PHE A 1 670 ? 36.394 94.231 -38.847 1.00 13.02 ? 670 PHE A CD1 1 ATOM 5288 C CD2 . PHE A 1 670 ? 35.242 93.633 -36.839 1.00 14.30 ? 670 PHE A CD2 1 ATOM 5289 C CE1 . PHE A 1 670 ? 37.495 94.635 -38.102 1.00 14.05 ? 670 PHE A CE1 1 ATOM 5290 C CE2 . PHE A 1 670 ? 36.336 94.028 -36.090 1.00 14.82 ? 670 PHE A CE2 1 ATOM 5291 C CZ . PHE A 1 670 ? 37.469 94.533 -36.721 1.00 14.06 ? 670 PHE A CZ 1 ATOM 5292 N N . GLY A 1 671 ? 31.906 91.154 -39.518 1.00 14.75 ? 671 GLY A N 1 ATOM 5293 C CA . GLY A 1 671 ? 30.645 90.776 -40.152 1.00 14.14 ? 671 GLY A CA 1 ATOM 5294 C C . GLY A 1 671 ? 29.520 90.661 -39.146 1.00 14.46 ? 671 GLY A C 1 ATOM 5295 O O . GLY A 1 671 ? 29.761 90.643 -37.948 1.00 11.97 ? 671 GLY A O 1 ATOM 5296 N N . ASP A 1 672 ? 28.275 90.631 -39.622 1.00 15.05 ? 672 ASP A N 1 ATOM 5297 C CA . ASP A 1 672 ? 27.145 90.448 -38.718 1.00 16.45 ? 672 ASP A CA 1 ATOM 5298 C C . ASP A 1 672 ? 27.119 88.959 -38.318 1.00 16.15 ? 672 ASP A C 1 ATOM 5299 O O . ASP A 1 672 ? 27.607 88.121 -39.050 1.00 14.53 ? 672 ASP A O 1 ATOM 5300 C CB . ASP A 1 672 ? 25.824 90.746 -39.422 1.00 18.47 ? 672 ASP A CB 1 ATOM 5301 C CG . ASP A 1 672 ? 25.620 92.221 -39.670 1.00 20.81 ? 672 ASP A CG 1 ATOM 5302 O OD1 . ASP A 1 672 ? 26.247 93.042 -38.974 1.00 22.81 ? 672 ASP A OD1 1 ATOM 5303 O OD2 . ASP A 1 672 ? 24.805 92.556 -40.538 1.00 23.90 ? 672 ASP A OD2 1 ATOM 5304 N N . PRO A 1 673 ? 26.554 88.636 -37.151 1.00 16.66 ? 673 PRO A N 1 ATOM 5305 C CA . PRO A 1 673 ? 26.478 87.240 -36.700 1.00 16.82 ? 673 PRO A CA 1 ATOM 5306 C C . PRO A 1 673 ? 25.873 86.398 -37.811 1.00 17.34 ? 673 PRO A C 1 ATOM 5307 O O . PRO A 1 673 ? 24.974 86.839 -38.505 1.00 17.39 ? 673 PRO A O 1 ATOM 5308 C CB . PRO A 1 673 ? 25.549 87.319 -35.505 1.00 16.73 ? 673 PRO A CB 1 ATOM 5309 C CG . PRO A 1 673 ? 25.836 88.640 -34.926 1.00 17.83 ? 673 PRO A CG 1 ATOM 5310 C CD . PRO A 1 673 ? 25.977 89.546 -36.144 1.00 17.08 ? 673 PRO A CD 1 ATOM 5311 N N . ARG A 1 674 ? 26.379 85.189 -37.982 1.00 18.36 ? 674 ARG A N 1 ATOM 5312 C CA . ARG A 1 674 ? 25.877 84.275 -38.994 1.00 18.79 ? 674 ARG A CA 1 ATOM 5313 C C . ARG A 1 674 ? 26.388 82.863 -38.698 1.00 19.15 ? 674 ARG A C 1 ATOM 5314 O O . ARG A 1 674 ? 27.393 82.690 -37.995 1.00 18.42 ? 674 ARG A O 1 ATOM 5315 C CB . ARG A 1 674 ? 26.354 84.708 -40.385 1.00 18.85 ? 674 ARG A CB 1 ATOM 5316 C CG . ARG A 1 674 ? 27.850 84.626 -40.586 1.00 20.65 ? 674 ARG A CG 1 ATOM 5317 C CD . ARG A 1 674 ? 28.180 84.755 -42.049 1.00 23.20 ? 674 ARG A CD 1 ATOM 5318 N NE . ARG A 1 674 ? 29.532 84.321 -42.338 1.00 25.74 ? 674 ARG A NE 1 ATOM 5319 C CZ . ARG A 1 674 ? 30.585 85.119 -42.483 1.00 28.22 ? 674 ARG A CZ 1 ATOM 5320 N NH1 . ARG A 1 674 ? 30.467 86.453 -42.368 1.00 29.52 ? 674 ARG A NH1 1 ATOM 5321 N NH2 . ARG A 1 674 ? 31.770 84.569 -42.758 1.00 29.02 ? 674 ARG A NH2 1 ATOM 5322 N N . GLU A 1 675 ? 25.712 81.850 -39.226 1.00 17.99 ? 675 GLU A N 1 ATOM 5323 C CA . GLU A 1 675 ? 26.177 80.499 -38.999 1.00 18.61 ? 675 GLU A CA 1 ATOM 5324 C C . GLU A 1 675 ? 27.508 80.299 -39.718 1.00 17.78 ? 675 GLU A C 1 ATOM 5325 O O . GLU A 1 675 ? 27.791 80.949 -40.725 1.00 17.38 ? 675 GLU A O 1 ATOM 5326 C CB . GLU A 1 675 ? 25.146 79.472 -39.490 1.00 20.96 ? 675 GLU A CB 1 ATOM 5327 C CG . GLU A 1 675 ? 23.801 79.595 -38.809 1.00 23.40 ? 675 GLU A CG 1 ATOM 5328 C CD . GLU A 1 675 ? 23.005 78.308 -38.839 1.00 26.82 ? 675 GLU A CD 1 ATOM 5329 O OE1 . GLU A 1 675 ? 23.159 77.549 -39.827 1.00 25.64 ? 675 GLU A OE1 1 ATOM 5330 O OE2 . GLU A 1 675 ? 22.219 78.074 -37.868 1.00 28.98 ? 675 GLU A OE2 1 ATOM 5331 N N . ILE A 1 676 ? 28.347 79.419 -39.180 1.00 17.26 ? 676 ILE A N 1 ATOM 5332 C CA . ILE A 1 676 ? 29.640 79.155 -39.789 1.00 17.33 ? 676 ILE A CA 1 ATOM 5333 C C . ILE A 1 676 ? 29.989 77.686 -39.684 1.00 16.18 ? 676 ILE A C 1 ATOM 5334 O O . ILE A 1 676 ? 29.458 76.975 -38.809 1.00 13.94 ? 676 ILE A O 1 ATOM 5335 C CB . ILE A 1 676 ? 30.771 79.933 -39.118 1.00 19.80 ? 676 ILE A CB 1 ATOM 5336 C CG1 . ILE A 1 676 ? 30.816 79.609 -37.644 1.00 21.69 ? 676 ILE A CG1 1 ATOM 5337 C CG2 . ILE A 1 676 ? 30.596 81.457 -39.314 1.00 22.53 ? 676 ILE A CG2 1 ATOM 5338 C CD1 . ILE A 1 676 ? 32.184 79.821 -37.088 1.00 25.29 ? 676 ILE A CD1 1 ATOM 5339 N N . SER A 1 677 ? 30.866 77.246 -40.583 1.00 15.19 ? 677 SER A N 1 ATOM 5340 C CA . SER A 1 677 ? 31.352 75.873 -40.608 1.00 18.06 ? 677 SER A CA 1 ATOM 5341 C C . SER A 1 677 ? 32.851 75.923 -40.716 1.00 17.41 ? 677 SER A C 1 ATOM 5342 O O . SER A 1 677 ? 33.399 76.807 -41.366 1.00 18.12 ? 677 SER A O 1 ATOM 5343 C CB . SER A 1 677 ? 30.820 75.093 -41.818 1.00 19.94 ? 677 SER A CB 1 ATOM 5344 O OG . SER A 1 677 ? 29.407 75.144 -41.821 1.00 26.19 ? 677 SER A OG 1 ATOM 5345 N N . LEU A 1 678 ? 33.511 74.967 -40.085 1.00 16.03 ? 678 LEU A N 1 ATOM 5346 C CA . LEU A 1 678 ? 34.958 74.904 -40.129 1.00 17.53 ? 678 LEU A CA 1 ATOM 5347 C C . LEU A 1 678 ? 35.415 73.464 -40.228 1.00 17.03 ? 678 LEU A C 1 ATOM 5348 O O . LEU A 1 678 ? 34.760 72.540 -39.736 1.00 15.64 ? 678 LEU A O 1 ATOM 5349 C CB . LEU A 1 678 ? 35.581 75.500 -38.856 1.00 18.27 ? 678 LEU A CB 1 ATOM 5350 C CG . LEU A 1 678 ? 35.492 76.994 -38.499 1.00 19.52 ? 678 LEU A CG 1 ATOM 5351 C CD1 . LEU A 1 678 ? 36.036 77.196 -37.064 1.00 20.91 ? 678 LEU A CD1 1 ATOM 5352 C CD2 . LEU A 1 678 ? 36.317 77.819 -39.466 1.00 21.68 ? 678 LEU A CD2 1 ATOM 5353 N N . ARG A 1 679 ? 36.557 73.289 -40.858 1.00 17.16 ? 679 ARG A N 1 ATOM 5354 C CA . ARG A 1 679 ? 37.147 71.980 -40.957 1.00 18.89 ? 679 ARG A CA 1 ATOM 5355 C C . ARG A 1 679 ? 38.675 72.111 -40.891 1.00 18.77 ? 679 ARG A C 1 ATOM 5356 O O . ARG A 1 679 ? 39.269 72.853 -41.680 1.00 19.79 ? 679 ARG A O 1 ATOM 5357 C CB . ARG A 1 679 ? 36.737 71.298 -42.266 1.00 20.05 ? 679 ARG A CB 1 ATOM 5358 C CG . ARG A 1 679 ? 37.373 69.925 -42.405 1.00 23.27 ? 679 ARG A CG 1 ATOM 5359 C CD . ARG A 1 679 ? 37.087 69.206 -43.726 1.00 25.88 ? 679 ARG A CD 1 ATOM 5360 N NE . ARG A 1 679 ? 37.466 67.809 -43.520 1.00 29.20 ? 679 ARG A NE 1 ATOM 5361 C CZ . ARG A 1 679 ? 37.566 66.871 -44.458 1.00 31.14 ? 679 ARG A CZ 1 ATOM 5362 N NH1 . ARG A 1 679 ? 37.314 67.149 -45.740 1.00 32.45 ? 679 ARG A NH1 1 ATOM 5363 N NH2 . ARG A 1 679 ? 37.936 65.642 -44.101 1.00 32.71 ? 679 ARG A NH2 1 ATOM 5364 N N . VAL A 1 680 ? 39.318 71.415 -39.951 1.00 17.53 ? 680 VAL A N 1 ATOM 5365 C CA . VAL A 1 680 ? 40.777 71.458 -39.894 1.00 17.31 ? 680 VAL A CA 1 ATOM 5366 C C . VAL A 1 680 ? 41.304 70.094 -40.356 1.00 19.42 ? 680 VAL A C 1 ATOM 5367 O O . VAL A 1 680 ? 40.740 69.032 -39.995 1.00 18.30 ? 680 VAL A O 1 ATOM 5368 C CB . VAL A 1 680 ? 41.295 71.760 -38.472 1.00 16.93 ? 680 VAL A CB 1 ATOM 5369 C CG1 . VAL A 1 680 ? 42.800 71.596 -38.420 1.00 15.19 ? 680 VAL A CG1 1 ATOM 5370 C CG2 . VAL A 1 680 ? 40.925 73.199 -38.063 1.00 15.17 ? 680 VAL A CG2 1 ATOM 5371 N N . GLY A 1 681 ? 42.381 70.123 -41.143 1.00 20.59 ? 681 GLY A N 1 ATOM 5372 C CA . GLY A 1 681 ? 42.972 68.894 -41.653 1.00 23.11 ? 681 GLY A CA 1 ATOM 5373 C C . GLY A 1 681 ? 41.923 68.053 -42.362 1.00 24.80 ? 681 GLY A C 1 ATOM 5374 O O . GLY A 1 681 ? 41.110 68.583 -43.116 1.00 23.18 ? 681 GLY A O 1 ATOM 5375 N N . ASN A 1 682 ? 41.943 66.741 -42.136 1.00 26.98 ? 682 ASN A N 1 ATOM 5376 C CA . ASN A 1 682 ? 40.935 65.851 -42.730 1.00 29.28 ? 682 ASN A CA 1 ATOM 5377 C C . ASN A 1 682 ? 39.931 65.540 -41.639 1.00 29.35 ? 682 ASN A C 1 ATOM 5378 O O . ASN A 1 682 ? 39.078 64.669 -41.803 1.00 31.56 ? 682 ASN A O 1 ATOM 5379 C CB . ASN A 1 682 ? 41.534 64.527 -43.159 1.00 30.87 ? 682 ASN A CB 1 ATOM 5380 C CG . ASN A 1 682 ? 42.654 64.697 -44.103 1.00 34.17 ? 682 ASN A CG 1 ATOM 5381 O OD1 . ASN A 1 682 ? 42.534 65.410 -45.116 1.00 35.81 ? 682 ASN A OD1 1 ATOM 5382 N ND2 . ASN A 1 682 ? 43.777 64.049 -43.796 1.00 35.26 ? 682 ASN A ND2 1 ATOM 5383 N N . GLY A 1 683 ? 40.044 66.253 -40.526 1.00 27.35 ? 683 GLY A N 1 ATOM 5384 C CA . GLY A 1 683 ? 39.170 65.997 -39.402 1.00 24.88 ? 683 GLY A CA 1 ATOM 5385 C C . GLY A 1 683 ? 37.708 66.200 -39.699 1.00 22.36 ? 683 GLY A C 1 ATOM 5386 O O . GLY A 1 683 ? 37.298 66.321 -40.864 1.00 21.87 ? 683 GLY A O 1 ATOM 5387 N N . PRO A 1 684 ? 36.889 66.238 -38.643 1.00 19.97 ? 684 PRO A N 1 ATOM 5388 C CA . PRO A 1 684 ? 35.455 66.437 -38.845 1.00 19.26 ? 684 PRO A CA 1 ATOM 5389 C C . PRO A 1 684 ? 35.171 67.881 -39.258 1.00 18.38 ? 684 PRO A C 1 ATOM 5390 O O . PRO A 1 684 ? 36.031 68.752 -39.141 1.00 17.59 ? 684 PRO A O 1 ATOM 5391 C CB . PRO A 1 684 ? 34.874 66.123 -37.475 1.00 18.91 ? 684 PRO A CB 1 ATOM 5392 C CG . PRO A 1 684 ? 35.955 66.656 -36.528 1.00 18.78 ? 684 PRO A CG 1 ATOM 5393 C CD . PRO A 1 684 ? 37.214 66.119 -37.209 1.00 20.19 ? 684 PRO A CD 1 ATOM 5394 N N . THR A 1 685 ? 33.965 68.119 -39.765 1.00 18.07 ? 685 THR A N 1 ATOM 5395 C CA . THR A 1 685 ? 33.563 69.466 -40.137 1.00 16.67 ? 685 THR A CA 1 ATOM 5396 C C . THR A 1 685 ? 32.505 69.805 -39.104 1.00 16.48 ? 685 THR A C 1 ATOM 5397 O O . THR A 1 685 ? 31.586 69.013 -38.854 1.00 15.86 ? 685 THR A O 1 ATOM 5398 C CB . THR A 1 685 ? 32.952 69.514 -41.554 1.00 17.22 ? 685 THR A CB 1 ATOM 5399 O OG1 . THR A 1 685 ? 33.956 69.162 -42.507 1.00 16.59 ? 685 THR A OG1 1 ATOM 5400 C CG2 . THR A 1 685 ? 32.412 70.899 -41.852 1.00 16.22 ? 685 THR A CG2 1 ATOM 5401 N N . LEU A 1 686 ? 32.641 70.978 -38.498 1.00 14.74 ? 686 LEU A N 1 ATOM 5402 C CA . LEU A 1 686 ? 31.723 71.380 -37.468 1.00 14.74 ? 686 LEU A CA 1 ATOM 5403 C C . LEU A 1 686 ? 30.960 72.624 -37.886 1.00 13.76 ? 686 LEU A C 1 ATOM 5404 O O . LEU A 1 686 ? 31.543 73.551 -38.452 1.00 13.40 ? 686 LEU A O 1 ATOM 5405 C CB . LEU A 1 686 ? 32.484 71.689 -36.174 1.00 15.05 ? 686 LEU A CB 1 ATOM 5406 C CG . LEU A 1 686 ? 33.504 70.729 -35.565 1.00 18.48 ? 686 LEU A CG 1 ATOM 5407 C CD1 . LEU A 1 686 ? 33.739 71.186 -34.113 1.00 18.54 ? 686 LEU A CD1 1 ATOM 5408 C CD2 . LEU A 1 686 ? 33.067 69.311 -35.603 1.00 17.35 ? 686 LEU A CD2 1 ATOM 5409 N N . ALA A 1 687 ? 29.671 72.642 -37.569 1.00 12.74 ? 687 ALA A N 1 ATOM 5410 C CA . ALA A 1 687 ? 28.820 73.771 -37.885 1.00 14.21 ? 687 ALA A CA 1 ATOM 5411 C C . ALA A 1 687 ? 28.381 74.430 -36.592 1.00 14.79 ? 687 ALA A C 1 ATOM 5412 O O . ALA A 1 687 ? 28.026 73.751 -35.615 1.00 15.79 ? 687 ALA A O 1 ATOM 5413 C CB . ALA A 1 687 ? 27.572 73.314 -38.704 1.00 14.79 ? 687 ALA A CB 1 ATOM 5414 N N . PHE A 1 688 ? 28.394 75.759 -36.597 1.00 14.03 ? 688 PHE A N 1 ATOM 5415 C CA . PHE A 1 688 ? 28.012 76.543 -35.448 1.00 12.58 ? 688 PHE A CA 1 ATOM 5416 C C . PHE A 1 688 ? 26.847 77.468 -35.780 1.00 12.87 ? 688 PHE A C 1 ATOM 5417 O O . PHE A 1 688 ? 26.684 77.907 -36.915 1.00 13.88 ? 688 PHE A O 1 ATOM 5418 C CB . PHE A 1 688 ? 29.190 77.413 -34.980 1.00 12.98 ? 688 PHE A CB 1 ATOM 5419 C CG . PHE A 1 688 ? 30.425 76.641 -34.656 1.00 11.39 ? 688 PHE A CG 1 ATOM 5420 C CD1 . PHE A 1 688 ? 31.238 76.144 -35.676 1.00 11.52 ? 688 PHE A CD1 1 ATOM 5421 C CD2 . PHE A 1 688 ? 30.757 76.383 -33.338 1.00 11.02 ? 688 PHE A CD2 1 ATOM 5422 C CE1 . PHE A 1 688 ? 32.367 75.397 -35.394 1.00 11.95 ? 688 PHE A CE1 1 ATOM 5423 C CE2 . PHE A 1 688 ? 31.893 75.634 -33.030 1.00 11.76 ? 688 PHE A CE2 1 ATOM 5424 C CZ . PHE A 1 688 ? 32.707 75.135 -34.058 1.00 9.96 ? 688 PHE A CZ 1 ATOM 5425 N N . SER A 1 689 ? 26.062 77.782 -34.765 1.00 13.22 ? 689 SER A N 1 ATOM 5426 C CA . SER A 1 689 ? 24.934 78.680 -34.913 1.00 14.88 ? 689 SER A CA 1 ATOM 5427 C C . SER A 1 689 ? 25.506 80.100 -34.891 1.00 14.83 ? 689 SER A C 1 ATOM 5428 O O . SER A 1 689 ? 26.688 80.307 -34.594 1.00 13.21 ? 689 SER A O 1 ATOM 5429 C CB . SER A 1 689 ? 23.970 78.518 -33.751 1.00 13.26 ? 689 SER A CB 1 ATOM 5430 O OG . SER A 1 689 ? 24.565 79.027 -32.587 1.00 16.24 ? 689 SER A OG 1 ATOM 5431 N N . GLU A 1 690 ? 24.655 81.069 -35.194 1.00 15.69 ? 690 GLU A N 1 ATOM 5432 C CA . GLU A 1 690 ? 25.106 82.437 -35.225 1.00 17.73 ? 690 GLU A CA 1 ATOM 5433 C C . GLU A 1 690 ? 25.475 82.944 -33.832 1.00 17.89 ? 690 GLU A C 1 ATOM 5434 O O . GLU A 1 690 ? 25.974 84.063 -33.696 1.00 17.24 ? 690 GLU A O 1 ATOM 5435 C CB . GLU A 1 690 ? 24.053 83.319 -35.904 1.00 20.00 ? 690 GLU A CB 1 ATOM 5436 C CG . GLU A 1 690 ? 22.872 83.680 -35.083 1.00 23.41 ? 690 GLU A CG 1 ATOM 5437 C CD . GLU A 1 690 ? 21.978 84.681 -35.834 1.00 27.04 ? 690 GLU A CD 1 ATOM 5438 O OE1 . GLU A 1 690 ? 21.388 84.291 -36.862 1.00 28.10 ? 690 GLU A OE1 1 ATOM 5439 O OE2 . GLU A 1 690 ? 21.882 85.861 -35.405 1.00 28.80 ? 690 GLU A OE2 1 ATOM 5440 N N . GLN A 1 691 ? 25.214 82.133 -32.800 1.00 17.14 ? 691 GLN A N 1 ATOM 5441 C CA . GLN A 1 691 ? 25.628 82.504 -31.444 1.00 16.93 ? 691 GLN A CA 1 ATOM 5442 C C . GLN A 1 691 ? 26.946 81.825 -31.062 1.00 15.42 ? 691 GLN A C 1 ATOM 5443 O O . GLN A 1 691 ? 27.343 81.835 -29.904 1.00 15.57 ? 691 GLN A O 1 ATOM 5444 C CB . GLN A 1 691 ? 24.591 82.127 -30.412 1.00 20.53 ? 691 GLN A CB 1 ATOM 5445 C CG . GLN A 1 691 ? 23.456 83.078 -30.384 1.00 25.76 ? 691 GLN A CG 1 ATOM 5446 C CD . GLN A 1 691 ? 22.193 82.327 -30.474 1.00 29.86 ? 691 GLN A CD 1 ATOM 5447 O OE1 . GLN A 1 691 ? 21.579 81.984 -29.449 1.00 32.00 ? 691 GLN A OE1 1 ATOM 5448 N NE2 . GLN A 1 691 ? 21.794 82.008 -31.700 1.00 32.67 ? 691 GLN A NE2 1 ATOM 5449 N N . GLY A 1 692 ? 27.614 81.226 -32.032 1.00 13.02 ? 692 GLY A N 1 ATOM 5450 C CA . GLY A 1 692 ? 28.900 80.615 -31.754 1.00 14.70 ? 692 GLY A CA 1 ATOM 5451 C C . GLY A 1 692 ? 28.858 79.275 -31.050 1.00 14.97 ? 692 GLY A C 1 ATOM 5452 O O . GLY A 1 692 ? 29.885 78.818 -30.543 1.00 16.58 ? 692 GLY A O 1 ATOM 5453 N N . LEU A 1 693 ? 27.692 78.635 -31.037 1.00 14.91 ? 693 LEU A N 1 ATOM 5454 C CA . LEU A 1 693 ? 27.571 77.322 -30.386 1.00 14.74 ? 693 LEU A CA 1 ATOM 5455 C C . LEU A 1 693 ? 27.481 76.183 -31.375 1.00 14.99 ? 693 LEU A C 1 ATOM 5456 O O . LEU A 1 693 ? 26.830 76.297 -32.427 1.00 12.92 ? 693 LEU A O 1 ATOM 5457 C CB . LEU A 1 693 ? 26.346 77.314 -29.478 1.00 15.42 ? 693 LEU A CB 1 ATOM 5458 C CG . LEU A 1 693 ? 26.515 78.275 -28.294 1.00 15.96 ? 693 LEU A CG 1 ATOM 5459 C CD1 . LEU A 1 693 ? 25.139 78.787 -27.853 1.00 18.38 ? 693 LEU A CD1 1 ATOM 5460 C CD2 . LEU A 1 693 ? 27.230 77.584 -27.159 1.00 14.43 ? 693 LEU A CD2 1 ATOM 5461 N N . LEU A 1 694 ? 28.123 75.069 -31.045 1.00 14.24 ? 694 LEU A N 1 ATOM 5462 C CA . LEU A 1 694 ? 28.102 73.928 -31.942 1.00 13.65 ? 694 LEU A CA 1 ATOM 5463 C C . LEU A 1 694 ? 26.655 73.567 -32.280 1.00 14.60 ? 694 LEU A C 1 ATOM 5464 O O . LEU A 1 694 ? 25.769 73.629 -31.428 1.00 12.83 ? 694 LEU A O 1 ATOM 5465 C CB . LEU A 1 694 ? 28.793 72.722 -31.292 1.00 14.70 ? 694 LEU A CB 1 ATOM 5466 C CG . LEU A 1 694 ? 28.930 71.448 -32.142 1.00 14.01 ? 694 LEU A CG 1 ATOM 5467 C CD1 . LEU A 1 694 ? 29.833 71.708 -33.336 1.00 14.19 ? 694 LEU A CD1 1 ATOM 5468 C CD2 . LEU A 1 694 ? 29.518 70.311 -31.277 1.00 13.40 ? 694 LEU A CD2 1 ATOM 5469 N N . LYS A 1 695 ? 26.465 73.162 -33.529 1.00 15.63 ? 695 LYS A N 1 ATOM 5470 C CA . LYS A 1 695 ? 25.170 72.788 -34.084 1.00 17.60 ? 695 LYS A CA 1 ATOM 5471 C C . LYS A 1 695 ? 25.237 71.371 -34.675 1.00 16.14 ? 695 LYS A C 1 ATOM 5472 O O . LYS A 1 695 ? 24.300 70.599 -34.577 1.00 16.63 ? 695 LYS A O 1 ATOM 5473 C CB . LYS A 1 695 ? 24.843 73.801 -35.193 1.00 20.55 ? 695 LYS A CB 1 ATOM 5474 C CG . LYS A 1 695 ? 23.551 73.654 -35.855 1.00 26.10 ? 695 LYS A CG 1 ATOM 5475 C CD . LYS A 1 695 ? 23.314 74.820 -36.846 1.00 28.65 ? 695 LYS A CD 1 ATOM 5476 C CE . LYS A 1 695 ? 21.970 74.621 -37.566 1.00 31.17 ? 695 LYS A CE 1 ATOM 5477 N NZ . LYS A 1 695 ? 21.631 75.668 -38.593 1.00 32.10 ? 695 LYS A NZ 1 ATOM 5478 N N . SER A 1 696 ? 26.339 71.029 -35.314 1.00 16.46 ? 696 SER A N 1 ATOM 5479 C CA . SER A 1 696 ? 26.429 69.705 -35.913 1.00 16.20 ? 696 SER A CA 1 ATOM 5480 C C . SER A 1 696 ? 27.857 69.293 -36.170 1.00 16.60 ? 696 SER A C 1 ATOM 5481 O O . SER A 1 696 ? 28.750 70.128 -36.284 1.00 16.98 ? 696 SER A O 1 ATOM 5482 C CB . SER A 1 696 ? 25.655 69.682 -37.239 1.00 16.52 ? 696 SER A CB 1 ATOM 5483 O OG . SER A 1 696 ? 26.305 70.455 -38.235 1.00 16.45 ? 696 SER A OG 1 ATOM 5484 N N . ILE A 1 697 ? 28.061 67.989 -36.296 1.00 16.53 ? 697 ILE A N 1 ATOM 5485 C CA . ILE A 1 697 ? 29.379 67.435 -36.562 1.00 16.57 ? 697 ILE A CA 1 ATOM 5486 C C . ILE A 1 697 ? 29.267 66.486 -37.748 1.00 18.46 ? 697 ILE A C 1 ATOM 5487 O O . ILE A 1 697 ? 28.372 65.604 -37.783 1.00 18.15 ? 697 ILE A O 1 ATOM 5488 C CB . ILE A 1 697 ? 29.914 66.615 -35.370 1.00 15.47 ? 697 ILE A CB 1 ATOM 5489 C CG1 . ILE A 1 697 ? 30.015 67.499 -34.119 1.00 15.22 ? 697 ILE A CG1 1 ATOM 5490 C CG2 . ILE A 1 697 ? 31.266 66.007 -35.719 1.00 15.06 ? 697 ILE A CG2 1 ATOM 5491 C CD1 . ILE A 1 697 ? 30.491 66.759 -32.824 1.00 13.69 ? 697 ILE A CD1 1 ATOM 5492 N N . GLN A 1 698 ? 30.143 66.677 -38.727 1.00 18.86 ? 698 GLN A N 1 ATOM 5493 C CA . GLN A 1 698 ? 30.166 65.806 -39.885 1.00 20.43 ? 698 GLN A CA 1 ATOM 5494 C C . GLN A 1 698 ? 31.505 65.100 -39.852 1.00 20.41 ? 698 GLN A C 1 ATOM 5495 O O . GLN A 1 698 ? 32.551 65.717 -40.076 1.00 20.43 ? 698 GLN A O 1 ATOM 5496 C CB . GLN A 1 698 ? 30.033 66.602 -41.189 1.00 21.43 ? 698 GLN A CB 1 ATOM 5497 C CG . GLN A 1 698 ? 29.923 65.681 -42.399 1.00 23.21 ? 698 GLN A CG 1 ATOM 5498 C CD . GLN A 1 698 ? 30.173 66.423 -43.708 1.00 25.72 ? 698 GLN A CD 1 ATOM 5499 O OE1 . GLN A 1 698 ? 31.065 67.262 -43.786 1.00 25.84 ? 698 GLN A OE1 1 ATOM 5500 N NE2 . GLN A 1 698 ? 29.399 66.102 -44.738 1.00 25.64 ? 698 GLN A NE2 1 ATOM 5501 N N . LEU A 1 699 ? 31.483 63.803 -39.588 1.00 21.02 ? 699 LEU A N 1 ATOM 5502 C CA . LEU A 1 699 ? 32.718 63.047 -39.467 1.00 23.14 ? 699 LEU A CA 1 ATOM 5503 C C . LEU A 1 699 ? 33.586 62.985 -40.712 1.00 24.83 ? 699 LEU A C 1 ATOM 5504 O O . LEU A 1 699 ? 34.801 63.167 -40.632 1.00 24.92 ? 699 LEU A O 1 ATOM 5505 C CB . LEU A 1 699 ? 32.416 61.620 -38.980 1.00 23.08 ? 699 LEU A CB 1 ATOM 5506 C CG . LEU A 1 699 ? 31.743 61.519 -37.600 1.00 23.32 ? 699 LEU A CG 1 ATOM 5507 C CD1 . LEU A 1 699 ? 31.608 60.068 -37.199 1.00 23.29 ? 699 LEU A CD1 1 ATOM 5508 C CD2 . LEU A 1 699 ? 32.565 62.249 -36.567 1.00 22.49 ? 699 LEU A CD2 1 ATOM 5509 N N . THR A 1 700 ? 32.970 62.741 -41.860 1.00 26.53 ? 700 THR A N 1 ATOM 5510 C CA . THR A 1 700 ? 33.722 62.617 -43.104 1.00 29.83 ? 700 THR A CA 1 ATOM 5511 C C . THR A 1 700 ? 33.078 63.420 -44.218 1.00 31.84 ? 700 THR A C 1 ATOM 5512 O O . THR A 1 700 ? 31.948 63.859 -44.092 1.00 32.05 ? 700 THR A O 1 ATOM 5513 C CB . THR A 1 700 ? 33.799 61.132 -43.565 1.00 28.95 ? 700 THR A CB 1 ATOM 5514 O OG1 . THR A 1 700 ? 32.468 60.608 -43.728 1.00 29.14 ? 700 THR A OG1 1 ATOM 5515 C CG2 . THR A 1 700 ? 34.529 60.291 -42.540 1.00 29.08 ? 700 THR A CG2 1 ATOM 5516 N N . GLN A 1 701 ? 33.820 63.594 -45.309 1.00 35.98 ? 701 GLN A N 1 ATOM 5517 C CA . GLN A 1 701 ? 33.356 64.324 -46.491 1.00 39.26 ? 701 GLN A CA 1 ATOM 5518 C C . GLN A 1 701 ? 31.910 64.034 -46.849 1.00 40.41 ? 701 GLN A C 1 ATOM 5519 O O . GLN A 1 701 ? 31.101 64.957 -47.006 1.00 40.90 ? 701 GLN A O 1 ATOM 5520 C CB . GLN A 1 701 ? 34.231 63.972 -47.704 1.00 41.31 ? 701 GLN A CB 1 ATOM 5521 C CG . GLN A 1 701 ? 35.521 64.763 -47.798 1.00 43.97 ? 701 GLN A CG 1 ATOM 5522 C CD . GLN A 1 701 ? 35.256 66.233 -48.087 1.00 46.15 ? 701 GLN A CD 1 ATOM 5523 O OE1 . GLN A 1 701 ? 36.185 67.040 -48.207 1.00 46.37 ? 701 GLN A OE1 1 ATOM 5524 N NE2 . GLN A 1 701 ? 33.973 66.589 -48.201 1.00 47.36 ? 701 GLN A NE2 1 ATOM 5525 N N . ASP A 1 702 ? 31.596 62.747 -46.965 1.00 41.94 ? 702 ASP A N 1 ATOM 5526 C CA . ASP A 1 702 ? 30.260 62.281 -47.343 1.00 44.02 ? 702 ASP A CA 1 ATOM 5527 C C . ASP A 1 702 ? 29.181 62.218 -46.246 1.00 43.38 ? 702 ASP A C 1 ATOM 5528 O O . ASP A 1 702 ? 28.040 62.671 -46.455 1.00 43.58 ? 702 ASP A O 1 ATOM 5529 C CB . ASP A 1 702 ? 30.382 60.896 -47.995 1.00 47.20 ? 702 ASP A CB 1 ATOM 5530 C CG . ASP A 1 702 ? 30.907 59.823 -47.025 1.00 50.50 ? 702 ASP A CG 1 ATOM 5531 O OD1 . ASP A 1 702 ? 32.073 59.945 -46.548 1.00 52.03 ? 702 ASP A OD1 1 ATOM 5532 O OD2 . ASP A 1 702 ? 30.147 58.857 -46.744 1.00 52.06 ? 702 ASP A OD2 1 ATOM 5533 N N . SER A 1 703 ? 29.557 61.655 -45.093 1.00 42.02 ? 703 SER A N 1 ATOM 5534 C CA . SER A 1 703 ? 28.659 61.475 -43.951 1.00 39.76 ? 703 SER A CA 1 ATOM 5535 C C . SER A 1 703 ? 27.734 62.649 -43.669 1.00 38.70 ? 703 SER A C 1 ATOM 5536 O O . SER A 1 703 ? 27.972 63.761 -44.115 1.00 38.48 ? 703 SER A O 1 ATOM 5537 C CB . SER A 1 703 ? 29.473 61.153 -42.685 1.00 40.33 ? 703 SER A CB 1 ATOM 5538 O OG . SER A 1 703 ? 30.330 62.226 -42.308 1.00 38.25 ? 703 SER A OG 1 ATOM 5539 N N . PRO A 1 704 ? 26.643 62.400 -42.931 1.00 36.76 ? 704 PRO A N 1 ATOM 5540 C CA . PRO A 1 704 ? 25.715 63.484 -42.614 1.00 35.56 ? 704 PRO A CA 1 ATOM 5541 C C . PRO A 1 704 ? 26.231 64.416 -41.521 1.00 33.65 ? 704 PRO A C 1 ATOM 5542 O O . PRO A 1 704 ? 27.199 64.103 -40.819 1.00 31.63 ? 704 PRO A O 1 ATOM 5543 C CB . PRO A 1 704 ? 24.453 62.744 -42.170 1.00 36.06 ? 704 PRO A CB 1 ATOM 5544 C CG . PRO A 1 704 ? 24.985 61.487 -41.573 1.00 36.70 ? 704 PRO A CG 1 ATOM 5545 C CD . PRO A 1 704 ? 26.090 61.092 -42.529 1.00 36.41 ? 704 PRO A CD 1 ATOM 5546 N N . HIS A 1 705 ? 25.574 65.570 -41.420 1.00 31.63 ? 705 HIS A N 1 ATOM 5547 C CA . HIS A 1 705 ? 25.868 66.567 -40.405 1.00 28.84 ? 705 HIS A CA 1 ATOM 5548 C C . HIS A 1 705 ? 25.029 66.123 -39.220 1.00 26.19 ? 705 HIS A C 1 ATOM 5549 O O . HIS A 1 705 ? 23.848 66.422 -39.135 1.00 25.50 ? 705 HIS A O 1 ATOM 5550 C CB . HIS A 1 705 ? 25.435 67.957 -40.887 1.00 31.13 ? 705 HIS A CB 1 ATOM 5551 C CG . HIS A 1 705 ? 26.280 68.480 -42.004 1.00 33.15 ? 705 HIS A CG 1 ATOM 5552 N ND1 . HIS A 1 705 ? 27.518 69.045 -41.790 1.00 33.02 ? 705 HIS A ND1 1 ATOM 5553 C CD2 . HIS A 1 705 ? 26.139 68.385 -43.349 1.00 34.19 ? 705 HIS A CD2 1 ATOM 5554 C CE1 . HIS A 1 705 ? 28.108 69.264 -42.951 1.00 34.66 ? 705 HIS A CE1 1 ATOM 5555 N NE2 . HIS A 1 705 ? 27.293 68.871 -43.915 1.00 35.29 ? 705 HIS A NE2 1 ATOM 5556 N N . VAL A 1 706 ? 25.653 65.391 -38.304 1.00 23.61 ? 706 VAL A N 1 ATOM 5557 C CA . VAL A 1 706 ? 24.958 64.883 -37.127 1.00 20.79 ? 706 VAL A CA 1 ATOM 5558 C C . VAL A 1 706 ? 24.621 65.978 -36.126 1.00 20.57 ? 706 VAL A C 1 ATOM 5559 O O . VAL A 1 706 ? 25.517 66.617 -35.600 1.00 20.89 ? 706 VAL A O 1 ATOM 5560 C CB . VAL A 1 706 ? 25.835 63.859 -36.405 1.00 20.23 ? 706 VAL A CB 1 ATOM 5561 C CG1 . VAL A 1 706 ? 25.098 63.298 -35.204 1.00 19.23 ? 706 VAL A CG1 1 ATOM 5562 C CG2 . VAL A 1 706 ? 26.283 62.790 -37.377 1.00 18.95 ? 706 VAL A CG2 1 ATOM 5563 N N . PRO A 1 707 ? 23.328 66.186 -35.828 1.00 19.87 ? 707 PRO A N 1 ATOM 5564 C CA . PRO A 1 707 ? 22.885 67.209 -34.871 1.00 19.56 ? 707 PRO A CA 1 ATOM 5565 C C . PRO A 1 707 ? 23.526 67.065 -33.473 1.00 19.16 ? 707 PRO A C 1 ATOM 5566 O O . PRO A 1 707 ? 23.207 66.120 -32.749 1.00 18.01 ? 707 PRO A O 1 ATOM 5567 C CB . PRO A 1 707 ? 21.375 66.970 -34.775 1.00 20.36 ? 707 PRO A CB 1 ATOM 5568 C CG . PRO A 1 707 ? 21.024 66.318 -36.075 1.00 20.24 ? 707 PRO A CG 1 ATOM 5569 C CD . PRO A 1 707 ? 22.182 65.405 -36.341 1.00 19.91 ? 707 PRO A CD 1 ATOM 5570 N N . VAL A 1 708 ? 24.395 68.010 -33.093 1.00 17.77 ? 708 VAL A N 1 ATOM 5571 C CA . VAL A 1 708 ? 25.040 68.003 -31.768 1.00 15.07 ? 708 VAL A CA 1 ATOM 5572 C C . VAL A 1 708 ? 25.016 69.478 -31.364 1.00 16.20 ? 708 VAL A C 1 ATOM 5573 O O . VAL A 1 708 ? 25.742 70.298 -31.912 1.00 13.97 ? 708 VAL A O 1 ATOM 5574 C CB . VAL A 1 708 ? 26.493 67.474 -31.843 1.00 13.86 ? 708 VAL A CB 1 ATOM 5575 C CG1 . VAL A 1 708 ? 27.146 67.497 -30.436 1.00 13.43 ? 708 VAL A CG1 1 ATOM 5576 C CG2 . VAL A 1 708 ? 26.506 66.048 -32.415 1.00 11.89 ? 708 VAL A CG2 1 ATOM 5577 N N . HIS A 1 709 ? 24.168 69.823 -30.414 1.00 16.37 ? 709 HIS A N 1 ATOM 5578 C CA . HIS A 1 709 ? 24.036 71.228 -30.051 1.00 17.55 ? 709 HIS A CA 1 ATOM 5579 C C . HIS A 1 709 ? 24.468 71.508 -28.610 1.00 16.07 ? 709 HIS A C 1 ATOM 5580 O O . HIS A 1 709 ? 24.044 70.798 -27.698 1.00 15.81 ? 709 HIS A O 1 ATOM 5581 C CB . HIS A 1 709 ? 22.562 71.691 -30.166 1.00 20.05 ? 709 HIS A CB 1 ATOM 5582 C CG . HIS A 1 709 ? 22.010 71.766 -31.564 1.00 24.56 ? 709 HIS A CG 1 ATOM 5583 N ND1 . HIS A 1 709 ? 21.850 70.660 -32.376 1.00 27.74 ? 709 HIS A ND1 1 ATOM 5584 C CD2 . HIS A 1 709 ? 21.474 72.810 -32.252 1.00 26.72 ? 709 HIS A CD2 1 ATOM 5585 C CE1 . HIS A 1 709 ? 21.240 71.014 -33.495 1.00 26.42 ? 709 HIS A CE1 1 ATOM 5586 N NE2 . HIS A 1 709 ? 21.000 72.315 -33.444 1.00 28.20 ? 709 HIS A NE2 1 ATOM 5587 N N . PHE A 1 710 ? 25.280 72.543 -28.413 1.00 13.52 ? 710 PHE A N 1 ATOM 5588 C CA . PHE A 1 710 ? 25.685 72.946 -27.072 1.00 12.67 ? 710 PHE A CA 1 ATOM 5589 C C . PHE A 1 710 ? 24.677 74.023 -26.655 1.00 12.51 ? 710 PHE A C 1 ATOM 5590 O O . PHE A 1 710 ? 24.269 74.865 -27.482 1.00 11.61 ? 710 PHE A O 1 ATOM 5591 C CB . PHE A 1 710 ? 27.096 73.553 -27.062 1.00 12.59 ? 710 PHE A CB 1 ATOM 5592 C CG . PHE A 1 710 ? 28.201 72.569 -26.682 1.00 13.82 ? 710 PHE A CG 1 ATOM 5593 C CD1 . PHE A 1 710 ? 29.272 72.347 -27.530 1.00 14.63 ? 710 PHE A CD1 1 ATOM 5594 C CD2 . PHE A 1 710 ? 28.180 71.915 -25.463 1.00 12.83 ? 710 PHE A CD2 1 ATOM 5595 C CE1 . PHE A 1 710 ? 30.323 71.483 -27.170 1.00 14.05 ? 710 PHE A CE1 1 ATOM 5596 C CE2 . PHE A 1 710 ? 29.207 71.059 -25.093 1.00 13.34 ? 710 PHE A CE2 1 ATOM 5597 C CZ . PHE A 1 710 ? 30.287 70.843 -25.951 1.00 12.91 ? 710 PHE A CZ 1 ATOM 5598 N N . LYS A 1 711 ? 24.273 73.996 -25.391 1.00 10.26 ? 711 LYS A N 1 ATOM 5599 C CA . LYS A 1 711 ? 23.328 74.984 -24.872 1.00 13.07 ? 711 LYS A CA 1 ATOM 5600 C C . LYS A 1 711 ? 23.719 75.205 -23.425 1.00 12.53 ? 711 LYS A C 1 ATOM 5601 O O . LYS A 1 711 ? 24.193 74.268 -22.778 1.00 12.85 ? 711 LYS A O 1 ATOM 5602 C CB . LYS A 1 711 ? 21.903 74.435 -24.890 1.00 14.90 ? 711 LYS A CB 1 ATOM 5603 C CG . LYS A 1 711 ? 20.857 75.434 -24.395 1.00 20.17 ? 711 LYS A CG 1 ATOM 5604 C CD . LYS A 1 711 ? 19.434 74.841 -24.514 1.00 22.60 ? 711 LYS A CD 1 ATOM 5605 C CE . LYS A 1 711 ? 19.039 74.606 -25.971 1.00 23.40 ? 711 LYS A CE 1 ATOM 5606 N NZ . LYS A 1 711 ? 17.787 73.752 -26.043 1.00 25.51 ? 711 LYS A NZ 1 ATOM 5607 N N . PHE A 1 712 ? 23.519 76.419 -22.920 1.00 9.98 ? 712 PHE A N 1 ATOM 5608 C CA . PHE A 1 712 ? 23.833 76.723 -21.541 1.00 10.34 ? 712 PHE A CA 1 ATOM 5609 C C . PHE A 1 712 ? 22.554 77.073 -20.828 1.00 10.51 ? 712 PHE A C 1 ATOM 5610 O O . PHE A 1 712 ? 21.716 77.835 -21.350 1.00 9.28 ? 712 PHE A O 1 ATOM 5611 C CB . PHE A 1 712 ? 24.835 77.890 -21.442 1.00 10.95 ? 712 PHE A CB 1 ATOM 5612 C CG . PHE A 1 712 ? 26.246 77.482 -21.749 1.00 10.51 ? 712 PHE A CG 1 ATOM 5613 C CD1 . PHE A 1 712 ? 26.733 77.533 -23.049 1.00 9.65 ? 712 PHE A CD1 1 ATOM 5614 C CD2 . PHE A 1 712 ? 27.072 76.991 -20.733 1.00 10.46 ? 712 PHE A CD2 1 ATOM 5615 C CE1 . PHE A 1 712 ? 28.017 77.099 -23.333 1.00 10.94 ? 712 PHE A CE1 1 ATOM 5616 C CE2 . PHE A 1 712 ? 28.346 76.562 -21.007 1.00 9.86 ? 712 PHE A CE2 1 ATOM 5617 C CZ . PHE A 1 712 ? 28.823 76.611 -22.307 1.00 9.77 ? 712 PHE A CZ 1 ATOM 5618 N N . LEU A 1 713 ? 22.380 76.494 -19.647 1.00 10.73 ? 713 LEU A N 1 ATOM 5619 C CA . LEU A 1 713 ? 21.178 76.743 -18.866 1.00 12.13 ? 713 LEU A CA 1 ATOM 5620 C C . LEU A 1 713 ? 21.493 77.050 -17.410 1.00 13.06 ? 713 LEU A C 1 ATOM 5621 O O . LEU A 1 713 ? 22.663 77.009 -16.988 1.00 13.82 ? 713 LEU A O 1 ATOM 5622 C CB . LEU A 1 713 ? 20.221 75.541 -18.975 1.00 11.08 ? 713 LEU A CB 1 ATOM 5623 C CG . LEU A 1 713 ? 19.841 75.132 -20.403 1.00 11.50 ? 713 LEU A CG 1 ATOM 5624 C CD1 . LEU A 1 713 ? 20.817 74.064 -20.891 1.00 13.15 ? 713 LEU A CD1 1 ATOM 5625 C CD2 . LEU A 1 713 ? 18.389 74.559 -20.436 1.00 12.30 ? 713 LEU A CD2 1 ATOM 5626 N N . LYS A 1 714 ? 20.468 77.403 -16.642 1.00 13.05 ? 714 LYS A N 1 ATOM 5627 C CA . LYS A 1 714 ? 20.662 77.684 -15.239 1.00 15.98 ? 714 LYS A CA 1 ATOM 5628 C C . LYS A 1 714 ? 19.579 77.067 -14.357 1.00 16.14 ? 714 LYS A C 1 ATOM 5629 O O . LYS A 1 714 ? 18.388 77.070 -14.703 1.00 16.36 ? 714 LYS A O 1 ATOM 5630 C CB . LYS A 1 714 ? 20.751 79.209 -14.971 1.00 19.05 ? 714 LYS A CB 1 ATOM 5631 C CG . LYS A 1 714 ? 19.681 80.052 -15.661 1.00 24.20 ? 714 LYS A CG 1 ATOM 5632 C CD . LYS A 1 714 ? 19.695 81.560 -15.256 1.00 28.52 ? 714 LYS A CD 1 ATOM 5633 C CE . LYS A 1 714 ? 21.042 82.273 -15.502 1.00 31.48 ? 714 LYS A CE 1 ATOM 5634 N NZ . LYS A 1 714 ? 20.996 83.763 -15.248 1.00 33.14 ? 714 LYS A NZ 1 ATOM 5635 N N . TYR A 1 715 ? 20.030 76.506 -13.227 1.00 14.61 ? 715 TYR A N 1 ATOM 5636 C CA . TYR A 1 715 ? 19.160 75.931 -12.227 1.00 14.46 ? 715 TYR A CA 1 ATOM 5637 C C . TYR A 1 715 ? 19.100 76.971 -11.137 1.00 14.80 ? 715 TYR A C 1 ATOM 5638 O O . TYR A 1 715 ? 20.066 77.714 -10.928 1.00 15.02 ? 715 TYR A O 1 ATOM 5639 C CB . TYR A 1 715 ? 19.760 74.657 -11.610 1.00 14.41 ? 715 TYR A CB 1 ATOM 5640 C CG . TYR A 1 715 ? 19.674 73.446 -12.500 1.00 13.16 ? 715 TYR A CG 1 ATOM 5641 C CD1 . TYR A 1 715 ? 20.786 72.998 -13.230 1.00 13.14 ? 715 TYR A CD1 1 ATOM 5642 C CD2 . TYR A 1 715 ? 18.470 72.731 -12.605 1.00 12.60 ? 715 TYR A CD2 1 ATOM 5643 C CE1 . TYR A 1 715 ? 20.700 71.839 -14.058 1.00 11.75 ? 715 TYR A CE1 1 ATOM 5644 C CE2 . TYR A 1 715 ? 18.375 71.603 -13.417 1.00 12.41 ? 715 TYR A CE2 1 ATOM 5645 C CZ . TYR A 1 715 ? 19.483 71.160 -14.135 1.00 12.57 ? 715 TYR A CZ 1 ATOM 5646 O OH . TYR A 1 715 ? 19.354 70.040 -14.917 1.00 10.04 ? 715 TYR A OH 1 ATOM 5647 N N . GLY A 1 716 ? 17.978 77.016 -10.438 1.00 15.50 ? 716 GLY A N 1 ATOM 5648 C CA . GLY A 1 716 ? 17.809 77.949 -9.334 1.00 14.39 ? 716 GLY A CA 1 ATOM 5649 C C . GLY A 1 716 ? 17.790 77.207 -8.004 1.00 16.63 ? 716 GLY A C 1 ATOM 5650 O O . GLY A 1 716 ? 18.230 76.045 -7.881 1.00 15.79 ? 716 GLY A O 1 ATOM 5651 N N . VAL A 1 717 ? 17.272 77.887 -6.991 1.00 16.89 ? 717 VAL A N 1 ATOM 5652 C CA . VAL A 1 717 ? 17.164 77.341 -5.646 1.00 18.05 ? 717 VAL A CA 1 ATOM 5653 C C . VAL A 1 717 ? 15.701 77.499 -5.210 1.00 19.55 ? 717 VAL A C 1 ATOM 5654 O O . VAL A 1 717 ? 15.020 78.426 -5.646 1.00 19.04 ? 717 VAL A O 1 ATOM 5655 C CB . VAL A 1 717 ? 18.075 78.112 -4.702 1.00 18.40 ? 717 VAL A CB 1 ATOM 5656 C CG1 . VAL A 1 717 ? 17.813 77.701 -3.276 1.00 20.41 ? 717 VAL A CG1 1 ATOM 5657 C CG2 . VAL A 1 717 ? 19.557 77.865 -5.099 1.00 18.48 ? 717 VAL A CG2 1 ATOM 5658 N N . ARG A 1 718 ? 15.217 76.600 -4.362 1.00 20.04 ? 718 ARG A N 1 ATOM 5659 C CA . ARG A 1 718 ? 13.823 76.668 -3.910 1.00 21.70 ? 718 ARG A CA 1 ATOM 5660 C C . ARG A 1 718 ? 13.557 77.841 -2.968 1.00 23.58 ? 718 ARG A C 1 ATOM 5661 O O . ARG A 1 718 ? 14.343 78.082 -2.066 1.00 23.06 ? 718 ARG A O 1 ATOM 5662 C CB . ARG A 1 718 ? 13.449 75.362 -3.203 1.00 20.09 ? 718 ARG A CB 1 ATOM 5663 C CG . ARG A 1 718 ? 13.539 74.184 -4.118 1.00 18.63 ? 718 ARG A CG 1 ATOM 5664 C CD . ARG A 1 718 ? 13.456 72.828 -3.422 1.00 16.62 ? 718 ARG A CD 1 ATOM 5665 N NE . ARG A 1 718 ? 13.716 71.795 -4.425 1.00 15.49 ? 718 ARG A NE 1 ATOM 5666 C CZ . ARG A 1 718 ? 13.735 70.485 -4.194 1.00 15.04 ? 718 ARG A CZ 1 ATOM 5667 N NH1 . ARG A 1 718 ? 13.484 70.006 -2.982 1.00 16.18 ? 718 ARG A NH1 1 ATOM 5668 N NH2 . ARG A 1 718 ? 14.064 69.660 -5.171 1.00 15.56 ? 718 ARG A NH2 1 ATOM 5669 N N . SER A 1 719 ? 12.434 78.540 -3.153 1.00 25.88 ? 719 SER A N 1 ATOM 5670 C CA . SER A 1 719 ? 12.094 79.668 -2.275 1.00 30.04 ? 719 SER A CA 1 ATOM 5671 C C . SER A 1 719 ? 11.501 79.205 -0.935 1.00 31.74 ? 719 SER A C 1 ATOM 5672 O O . SER A 1 719 ? 11.481 79.946 0.033 1.00 32.95 ? 719 SER A O 1 ATOM 5673 C CB . SER A 1 719 ? 11.126 80.623 -2.980 1.00 30.50 ? 719 SER A CB 1 ATOM 5674 O OG . SER A 1 719 ? 10.008 79.910 -3.449 1.00 33.00 ? 719 SER A OG 1 ATOM 5675 N N . HIS A 1 720 ? 11.016 77.975 -0.881 1.00 33.53 ? 720 HIS A N 1 ATOM 5676 C CA . HIS A 1 720 ? 10.503 77.446 0.371 1.00 35.40 ? 720 HIS A CA 1 ATOM 5677 C C . HIS A 1 720 ? 11.025 76.006 0.467 1.00 34.40 ? 720 HIS A C 1 ATOM 5678 O O . HIS A 1 720 ? 11.235 75.337 -0.548 1.00 34.21 ? 720 HIS A O 1 ATOM 5679 C CB . HIS A 1 720 ? 8.970 77.495 0.391 1.00 38.74 ? 720 HIS A CB 1 ATOM 5680 C CG . HIS A 1 720 ? 8.319 76.525 -0.545 1.00 42.74 ? 720 HIS A CG 1 ATOM 5681 N ND1 . HIS A 1 720 ? 8.118 75.196 -0.219 1.00 44.16 ? 720 HIS A ND1 1 ATOM 5682 C CD2 . HIS A 1 720 ? 7.843 76.683 -1.805 1.00 44.26 ? 720 HIS A CD2 1 ATOM 5683 C CE1 . HIS A 1 720 ? 7.549 74.577 -1.241 1.00 45.66 ? 720 HIS A CE1 1 ATOM 5684 N NE2 . HIS A 1 720 ? 7.372 75.456 -2.217 1.00 46.49 ? 720 HIS A NE2 1 ATOM 5685 N N . GLY A 1 721 ? 11.266 75.530 1.680 1.00 32.55 ? 721 GLY A N 1 ATOM 5686 C CA . GLY A 1 721 ? 11.779 74.178 1.802 1.00 29.83 ? 721 GLY A CA 1 ATOM 5687 C C . GLY A 1 721 ? 13.294 74.182 1.904 1.00 27.14 ? 721 GLY A C 1 ATOM 5688 O O . GLY A 1 721 ? 13.889 75.222 2.187 1.00 26.01 ? 721 GLY A O 1 ATOM 5689 N N . ASP A 1 722 ? 13.913 73.030 1.646 1.00 24.74 ? 722 ASP A N 1 ATOM 5690 C CA . ASP A 1 722 ? 15.363 72.886 1.759 1.00 22.47 ? 722 ASP A CA 1 ATOM 5691 C C . ASP A 1 722 ? 16.111 73.607 0.650 1.00 21.52 ? 722 ASP A C 1 ATOM 5692 O O . ASP A 1 722 ? 15.707 73.561 -0.517 1.00 21.62 ? 722 ASP A O 1 ATOM 5693 C CB . ASP A 1 722 ? 15.743 71.401 1.787 1.00 20.59 ? 722 ASP A CB 1 ATOM 5694 C CG . ASP A 1 722 ? 15.162 70.672 3.006 1.00 22.24 ? 722 ASP A CG 1 ATOM 5695 O OD1 . ASP A 1 722 ? 15.007 69.429 2.952 1.00 19.91 ? 722 ASP A OD1 1 ATOM 5696 O OD2 . ASP A 1 722 ? 14.879 71.339 4.026 1.00 19.92 ? 722 ASP A OD2 1 ATOM 5697 N N . ARG A 1 723 ? 17.192 74.282 1.044 1.00 20.62 ? 723 ARG A N 1 ATOM 5698 C CA . ARG A 1 723 ? 18.049 75.025 0.124 1.00 20.72 ? 723 ARG A CA 1 ATOM 5699 C C . ARG A 1 723 ? 19.322 74.297 -0.308 1.00 18.64 ? 723 ARG A C 1 ATOM 5700 O O . ARG A 1 723 ? 19.968 73.602 0.477 1.00 17.58 ? 723 ARG A O 1 ATOM 5701 C CB . ARG A 1 723 ? 18.483 76.358 0.736 1.00 23.79 ? 723 ARG A CB 1 ATOM 5702 C CG . ARG A 1 723 ? 17.551 77.527 0.433 1.00 31.11 ? 723 ARG A CG 1 ATOM 5703 C CD . ARG A 1 723 ? 16.187 77.328 1.053 1.00 35.57 ? 723 ARG A CD 1 ATOM 5704 N NE . ARG A 1 723 ? 15.369 78.548 1.079 1.00 40.14 ? 723 ARG A NE 1 ATOM 5705 C CZ . ARG A 1 723 ? 15.769 79.711 1.600 1.00 42.50 ? 723 ARG A CZ 1 ATOM 5706 N NH1 . ARG A 1 723 ? 16.987 79.835 2.127 1.00 43.39 ? 723 ARG A NH1 1 ATOM 5707 N NH2 . ARG A 1 723 ? 14.930 80.740 1.652 1.00 43.36 ? 723 ARG A NH2 1 ATOM 5708 N N . SER A 1 724 ? 19.671 74.465 -1.575 1.00 16.23 ? 724 SER A N 1 ATOM 5709 C CA . SER A 1 724 ? 20.895 73.894 -2.100 1.00 15.42 ? 724 SER A CA 1 ATOM 5710 C C . SER A 1 724 ? 22.062 74.587 -1.378 1.00 15.35 ? 724 SER A C 1 ATOM 5711 O O . SER A 1 724 ? 21.972 75.800 -1.056 1.00 14.68 ? 724 SER A O 1 ATOM 5712 C CB . SER A 1 724 ? 21.007 74.191 -3.594 1.00 12.68 ? 724 SER A CB 1 ATOM 5713 O OG . SER A 1 724 ? 19.957 73.579 -4.330 1.00 15.50 ? 724 SER A OG 1 ATOM 5714 N N . GLY A 1 725 ? 23.147 73.842 -1.154 1.00 14.10 ? 725 GLY A N 1 ATOM 5715 C CA . GLY A 1 725 ? 24.344 74.392 -0.519 1.00 12.57 ? 725 GLY A CA 1 ATOM 5716 C C . GLY A 1 725 ? 25.582 73.706 -1.091 1.00 13.32 ? 725 GLY A C 1 ATOM 5717 O O . GLY A 1 725 ? 25.522 73.139 -2.208 1.00 13.39 ? 725 GLY A O 1 ATOM 5718 N N . ALA A 1 726 ? 26.700 73.732 -0.355 1.00 10.32 ? 726 ALA A N 1 ATOM 5719 C CA . ALA A 1 726 ? 27.946 73.103 -0.825 1.00 9.83 ? 726 ALA A CA 1 ATOM 5720 C C . ALA A 1 726 ? 27.768 71.593 -1.059 1.00 9.41 ? 726 ALA A C 1 ATOM 5721 O O . ALA A 1 726 ? 28.401 71.019 -1.944 1.00 10.34 ? 726 ALA A O 1 ATOM 5722 C CB . ALA A 1 726 ? 29.078 73.330 0.199 1.00 9.46 ? 726 ALA A CB 1 ATOM 5723 N N . TYR A 1 727 ? 26.928 70.953 -0.245 1.00 9.00 ? 727 TYR A N 1 ATOM 5724 C CA . TYR A 1 727 ? 26.698 69.508 -0.369 1.00 9.62 ? 727 TYR A CA 1 ATOM 5725 C C . TYR A 1 727 ? 25.501 69.153 -1.244 1.00 9.38 ? 727 TYR A C 1 ATOM 5726 O O . TYR A 1 727 ? 25.597 68.333 -2.164 1.00 8.93 ? 727 TYR A O 1 ATOM 5727 C CB . TYR A 1 727 ? 26.418 68.881 0.997 1.00 8.54 ? 727 TYR A CB 1 ATOM 5728 C CG . TYR A 1 727 ? 27.447 69.144 2.055 1.00 9.78 ? 727 TYR A CG 1 ATOM 5729 C CD1 . TYR A 1 727 ? 27.412 70.311 2.818 1.00 9.81 ? 727 TYR A CD1 1 ATOM 5730 C CD2 . TYR A 1 727 ? 28.461 68.201 2.316 1.00 7.38 ? 727 TYR A CD2 1 ATOM 5731 C CE1 . TYR A 1 727 ? 28.374 70.547 3.835 1.00 10.81 ? 727 TYR A CE1 1 ATOM 5732 C CE2 . TYR A 1 727 ? 29.412 68.416 3.327 1.00 7.90 ? 727 TYR A CE2 1 ATOM 5733 C CZ . TYR A 1 727 ? 29.365 69.588 4.083 1.00 8.25 ? 727 TYR A CZ 1 ATOM 5734 O OH . TYR A 1 727 ? 30.263 69.777 5.117 1.00 8.08 ? 727 TYR A OH 1 ATOM 5735 N N . LEU A 1 728 ? 24.362 69.775 -0.934 1.00 9.08 ? 728 LEU A N 1 ATOM 5736 C CA . LEU A 1 728 ? 23.105 69.451 -1.611 1.00 10.71 ? 728 LEU A CA 1 ATOM 5737 C C . LEU A 1 728 ? 22.749 70.174 -2.919 1.00 11.03 ? 728 LEU A C 1 ATOM 5738 O O . LEU A 1 728 ? 22.956 71.380 -3.068 1.00 11.10 ? 728 LEU A O 1 ATOM 5739 C CB . LEU A 1 728 ? 21.923 69.657 -0.618 1.00 10.68 ? 728 LEU A CB 1 ATOM 5740 C CG . LEU A 1 728 ? 22.036 69.070 0.802 1.00 9.77 ? 728 LEU A CG 1 ATOM 5741 C CD1 . LEU A 1 728 ? 20.717 69.216 1.581 1.00 10.57 ? 728 LEU A CD1 1 ATOM 5742 C CD2 . LEU A 1 728 ? 22.399 67.617 0.692 1.00 12.28 ? 728 LEU A CD2 1 ATOM 5743 N N . PHE A 1 729 ? 22.203 69.420 -3.868 1.00 12.53 ? 729 PHE A N 1 ATOM 5744 C CA . PHE A 1 729 ? 21.705 70.014 -5.111 1.00 12.57 ? 729 PHE A CA 1 ATOM 5745 C C . PHE A 1 729 ? 20.151 69.836 -4.986 1.00 13.50 ? 729 PHE A C 1 ATOM 5746 O O . PHE A 1 729 ? 19.644 68.721 -5.113 1.00 11.45 ? 729 PHE A O 1 ATOM 5747 C CB . PHE A 1 729 ? 22.225 69.241 -6.313 1.00 12.16 ? 729 PHE A CB 1 ATOM 5748 C CG . PHE A 1 729 ? 21.679 69.715 -7.642 1.00 13.18 ? 729 PHE A CG 1 ATOM 5749 C CD1 . PHE A 1 729 ? 21.563 68.822 -8.705 1.00 12.17 ? 729 PHE A CD1 1 ATOM 5750 C CD2 . PHE A 1 729 ? 21.345 71.058 -7.852 1.00 13.45 ? 729 PHE A CD2 1 ATOM 5751 C CE1 . PHE A 1 729 ? 21.118 69.258 -9.963 1.00 12.00 ? 729 PHE A CE1 1 ATOM 5752 C CE2 . PHE A 1 729 ? 20.906 71.503 -9.096 1.00 12.03 ? 729 PHE A CE2 1 ATOM 5753 C CZ . PHE A 1 729 ? 20.786 70.610 -10.155 1.00 11.54 ? 729 PHE A CZ 1 ATOM 5754 N N . LEU A 1 730 ? 19.429 70.937 -4.742 1.00 14.21 ? 730 LEU A N 1 ATOM 5755 C CA . LEU A 1 730 ? 17.969 70.961 -4.580 1.00 14.23 ? 730 LEU A CA 1 ATOM 5756 C C . LEU A 1 730 ? 17.387 71.975 -5.560 1.00 15.16 ? 730 LEU A C 1 ATOM 5757 O O . LEU A 1 730 ? 16.918 73.057 -5.162 1.00 14.88 ? 730 LEU A O 1 ATOM 5758 C CB . LEU A 1 730 ? 17.618 71.369 -3.144 1.00 12.95 ? 730 LEU A CB 1 ATOM 5759 C CG . LEU A 1 730 ? 17.995 70.266 -2.135 1.00 10.56 ? 730 LEU A CG 1 ATOM 5760 C CD1 . LEU A 1 730 ? 17.984 70.804 -0.735 1.00 13.33 ? 730 LEU A CD1 1 ATOM 5761 C CD2 . LEU A 1 730 ? 17.019 69.101 -2.266 1.00 10.00 ? 730 LEU A CD2 1 ATOM 5762 N N . PRO A 1 731 ? 17.399 71.635 -6.856 1.00 14.61 ? 731 PRO A N 1 ATOM 5763 C CA . PRO A 1 731 ? 16.883 72.544 -7.881 1.00 15.90 ? 731 PRO A CA 1 ATOM 5764 C C . PRO A 1 731 ? 15.412 72.899 -7.774 1.00 16.85 ? 731 PRO A C 1 ATOM 5765 O O . PRO A 1 731 ? 14.599 72.105 -7.312 1.00 17.66 ? 731 PRO A O 1 ATOM 5766 C CB . PRO A 1 731 ? 17.203 71.813 -9.189 1.00 14.65 ? 731 PRO A CB 1 ATOM 5767 C CG . PRO A 1 731 ? 17.106 70.350 -8.772 1.00 14.51 ? 731 PRO A CG 1 ATOM 5768 C CD . PRO A 1 731 ? 17.748 70.321 -7.423 1.00 13.38 ? 731 PRO A CD 1 ATOM 5769 N N . ASN A 1 732 ? 15.068 74.113 -8.186 1.00 18.47 ? 732 ASN A N 1 ATOM 5770 C CA . ASN A 1 732 ? 13.671 74.503 -8.189 1.00 18.43 ? 732 ASN A CA 1 ATOM 5771 C C . ASN A 1 732 ? 13.161 74.191 -9.591 1.00 17.81 ? 732 ASN A C 1 ATOM 5772 O O . ASN A 1 732 ? 12.722 75.074 -10.316 1.00 18.51 ? 732 ASN A O 1 ATOM 5773 C CB . ASN A 1 732 ? 13.519 75.988 -7.860 1.00 20.22 ? 732 ASN A CB 1 ATOM 5774 C CG . ASN A 1 732 ? 14.143 76.892 -8.903 1.00 22.23 ? 732 ASN A CG 1 ATOM 5775 O OD1 . ASN A 1 732 ? 15.114 76.524 -9.575 1.00 22.29 ? 732 ASN A OD1 1 ATOM 5776 N ND2 . ASN A 1 732 ? 13.597 78.109 -9.030 1.00 23.79 ? 732 ASN A ND2 1 ATOM 5777 N N . GLY A 1 733 ? 13.261 72.919 -9.971 1.00 16.77 ? 733 GLY A N 1 ATOM 5778 C CA . GLY A 1 733 ? 12.784 72.457 -11.261 1.00 16.91 ? 733 GLY A CA 1 ATOM 5779 C C . GLY A 1 733 ? 13.882 72.339 -12.314 1.00 17.58 ? 733 GLY A C 1 ATOM 5780 O O . GLY A 1 733 ? 15.041 72.653 -12.040 1.00 15.67 ? 733 GLY A O 1 ATOM 5781 N N . PRO A 1 734 ? 13.533 71.884 -13.534 1.00 17.45 ? 734 PRO A N 1 ATOM 5782 C CA . PRO A 1 734 ? 14.447 71.715 -14.666 1.00 16.75 ? 734 PRO A CA 1 ATOM 5783 C C . PRO A 1 734 ? 15.078 73.068 -14.974 1.00 16.35 ? 734 PRO A C 1 ATOM 5784 O O . PRO A 1 734 ? 14.487 74.111 -14.706 1.00 15.68 ? 734 PRO A O 1 ATOM 5785 C CB . PRO A 1 734 ? 13.523 71.271 -15.792 1.00 16.53 ? 734 PRO A CB 1 ATOM 5786 C CG . PRO A 1 734 ? 12.440 70.550 -15.067 1.00 18.15 ? 734 PRO A CG 1 ATOM 5787 C CD . PRO A 1 734 ? 12.177 71.419 -13.883 1.00 17.22 ? 734 PRO A CD 1 ATOM 5788 N N . ALA A 1 735 ? 16.245 73.046 -15.602 1.00 16.66 ? 735 ALA A N 1 ATOM 5789 C CA . ALA A 1 735 ? 16.960 74.273 -15.911 1.00 16.74 ? 735 ALA A CA 1 ATOM 5790 C C . ALA A 1 735 ? 16.272 75.120 -16.988 1.00 18.05 ? 735 ALA A C 1 ATOM 5791 O O . ALA A 1 735 ? 15.568 74.584 -17.834 1.00 18.69 ? 735 ALA A O 1 ATOM 5792 C CB . ALA A 1 735 ? 18.389 73.936 -16.339 1.00 15.15 ? 735 ALA A CB 1 ATOM 5793 N N . SER A 1 736 ? 16.510 76.435 -16.950 1.00 18.01 ? 736 SER A N 1 ATOM 5794 C CA . SER A 1 736 ? 15.951 77.382 -17.911 1.00 17.86 ? 736 SER A CA 1 ATOM 5795 C C . SER A 1 736 ? 17.101 77.881 -18.769 1.00 18.25 ? 736 SER A C 1 ATOM 5796 O O . SER A 1 736 ? 18.211 78.093 -18.278 1.00 15.68 ? 736 SER A O 1 ATOM 5797 C CB . SER A 1 736 ? 15.340 78.560 -17.174 1.00 18.67 ? 736 SER A CB 1 ATOM 5798 O OG . SER A 1 736 ? 14.462 78.075 -16.171 1.00 22.48 ? 736 SER A OG 1 ATOM 5799 N N . PRO A 1 737 ? 16.851 78.111 -20.057 1.00 19.25 ? 737 PRO A N 1 ATOM 5800 C CA . PRO A 1 737 ? 17.970 78.584 -20.886 1.00 20.49 ? 737 PRO A CA 1 ATOM 5801 C C . PRO A 1 737 ? 18.559 79.926 -20.426 1.00 21.24 ? 737 PRO A C 1 ATOM 5802 O O . PRO A 1 737 ? 17.850 80.788 -19.902 1.00 21.81 ? 737 PRO A O 1 ATOM 5803 C CB . PRO A 1 737 ? 17.354 78.684 -22.296 1.00 21.34 ? 737 PRO A CB 1 ATOM 5804 C CG . PRO A 1 737 ? 16.101 77.774 -22.222 1.00 21.60 ? 737 PRO A CG 1 ATOM 5805 C CD . PRO A 1 737 ? 15.594 78.065 -20.820 1.00 20.19 ? 737 PRO A CD 1 ATOM 5806 N N . VAL A 1 738 ? 19.868 80.082 -20.584 1.00 22.39 ? 738 VAL A N 1 ATOM 5807 C CA . VAL A 1 738 ? 20.521 81.342 -20.249 1.00 22.60 ? 738 VAL A CA 1 ATOM 5808 C C . VAL A 1 738 ? 20.159 82.257 -21.450 1.00 23.56 ? 738 VAL A C 1 ATOM 5809 O O . VAL A 1 738 ? 20.265 81.829 -22.603 1.00 22.14 ? 738 VAL A O 1 ATOM 5810 C CB . VAL A 1 738 ? 22.073 81.160 -20.176 1.00 23.45 ? 738 VAL A CB 1 ATOM 5811 C CG1 . VAL A 1 738 ? 22.767 82.534 -20.168 1.00 23.45 ? 738 VAL A CG1 1 ATOM 5812 C CG2 . VAL A 1 738 ? 22.454 80.359 -18.918 1.00 23.07 ? 738 VAL A CG2 1 ATOM 5813 N N . GLU A 1 739 ? 19.690 83.473 -21.192 1.00 24.37 ? 739 GLU A N 1 ATOM 5814 C CA . GLU A 1 739 ? 19.346 84.387 -22.290 1.00 25.13 ? 739 GLU A CA 1 ATOM 5815 C C . GLU A 1 739 ? 20.672 84.904 -22.811 1.00 24.21 ? 739 GLU A C 1 ATOM 5816 O O . GLU A 1 739 ? 21.438 85.530 -22.076 1.00 23.33 ? 739 GLU A O 1 ATOM 5817 C CB . GLU A 1 739 ? 18.496 85.553 -21.793 1.00 27.97 ? 739 GLU A CB 1 ATOM 5818 C CG . GLU A 1 739 ? 17.051 85.190 -21.526 1.00 33.36 ? 739 GLU A CG 1 ATOM 5819 C CD . GLU A 1 739 ? 16.220 86.398 -21.061 1.00 36.59 ? 739 GLU A CD 1 ATOM 5820 O OE1 . GLU A 1 739 ? 15.015 86.211 -20.780 1.00 39.27 ? 739 GLU A OE1 1 ATOM 5821 O OE2 . GLU A 1 739 ? 16.766 87.525 -20.976 1.00 37.49 ? 739 GLU A OE2 1 ATOM 5822 N N . LEU A 1 740 ? 20.928 84.643 -24.082 1.00 23.85 ? 740 LEU A N 1 ATOM 5823 C CA . LEU A 1 740 ? 22.199 84.996 -24.691 1.00 23.60 ? 740 LEU A CA 1 ATOM 5824 C C . LEU A 1 740 ? 22.344 86.368 -25.319 1.00 24.09 ? 740 LEU A C 1 ATOM 5825 O O . LEU A 1 740 ? 23.468 86.769 -25.617 1.00 24.72 ? 740 LEU A O 1 ATOM 5826 C CB . LEU A 1 740 ? 22.550 83.932 -25.729 1.00 22.65 ? 740 LEU A CB 1 ATOM 5827 C CG . LEU A 1 740 ? 22.518 82.474 -25.231 1.00 22.28 ? 740 LEU A CG 1 ATOM 5828 C CD1 . LEU A 1 740 ? 22.932 81.567 -26.351 1.00 21.23 ? 740 LEU A CD1 1 ATOM 5829 C CD2 . LEU A 1 740 ? 23.455 82.297 -24.019 1.00 22.17 ? 740 LEU A CD2 1 ATOM 5830 N N . GLY A 1 741 ? 21.239 87.087 -25.529 1.00 23.65 ? 741 GLY A N 1 ATOM 5831 C CA . GLY A 1 741 ? 21.343 88.389 -26.172 1.00 24.61 ? 741 GLY A CA 1 ATOM 5832 C C . GLY A 1 741 ? 21.921 88.161 -27.560 1.00 24.57 ? 741 GLY A C 1 ATOM 5833 O O . GLY A 1 741 ? 21.630 87.142 -28.174 1.00 25.79 ? 741 GLY A O 1 ATOM 5834 N N . GLN A 1 742 ? 22.731 89.078 -28.082 1.00 25.74 ? 742 GLN A N 1 ATOM 5835 C CA . GLN A 1 742 ? 23.341 88.857 -29.407 1.00 25.78 ? 742 GLN A CA 1 ATOM 5836 C C . GLN A 1 742 ? 24.845 88.827 -29.102 1.00 23.74 ? 742 GLN A C 1 ATOM 5837 O O . GLN A 1 742 ? 25.532 89.818 -29.234 1.00 24.65 ? 742 GLN A O 1 ATOM 5838 C CB . GLN A 1 742 ? 22.984 90.007 -30.369 1.00 28.87 ? 742 GLN A CB 1 ATOM 5839 C CG . GLN A 1 742 ? 23.138 89.648 -31.863 1.00 32.77 ? 742 GLN A CG 1 ATOM 5840 C CD . GLN A 1 742 ? 22.440 90.635 -32.829 1.00 36.25 ? 742 GLN A CD 1 ATOM 5841 O OE1 . GLN A 1 742 ? 21.580 91.458 -32.427 1.00 37.47 ? 742 GLN A OE1 1 ATOM 5842 N NE2 . GLN A 1 742 ? 22.797 90.542 -34.111 1.00 36.20 ? 742 GLN A NE2 1 ATOM 5843 N N . PRO A 1 743 ? 25.367 87.668 -28.687 1.00 21.82 ? 743 PRO A N 1 ATOM 5844 C CA . PRO A 1 743 ? 26.793 87.561 -28.344 1.00 19.38 ? 743 PRO A CA 1 ATOM 5845 C C . PRO A 1 743 ? 27.839 87.780 -29.425 1.00 17.72 ? 743 PRO A C 1 ATOM 5846 O O . PRO A 1 743 ? 27.607 87.510 -30.601 1.00 15.37 ? 743 PRO A O 1 ATOM 5847 C CB . PRO A 1 743 ? 26.889 86.173 -27.727 1.00 18.90 ? 743 PRO A CB 1 ATOM 5848 C CG . PRO A 1 743 ? 25.884 85.381 -28.569 1.00 20.92 ? 743 PRO A CG 1 ATOM 5849 C CD . PRO A 1 743 ? 24.701 86.352 -28.625 1.00 20.26 ? 743 PRO A CD 1 ATOM 5850 N N . VAL A 1 744 ? 29.010 88.259 -29.000 1.00 14.94 ? 744 VAL A N 1 ATOM 5851 C CA . VAL A 1 744 ? 30.108 88.481 -29.930 1.00 14.30 ? 744 VAL A CA 1 ATOM 5852 C C . VAL A 1 744 ? 30.832 87.155 -30.180 1.00 13.55 ? 744 VAL A C 1 ATOM 5853 O O . VAL A 1 744 ? 31.227 86.465 -29.245 1.00 14.07 ? 744 VAL A O 1 ATOM 5854 C CB . VAL A 1 744 ? 31.105 89.503 -29.374 1.00 14.88 ? 744 VAL A CB 1 ATOM 5855 C CG1 . VAL A 1 744 ? 32.324 89.577 -30.297 1.00 12.15 ? 744 VAL A CG1 1 ATOM 5856 C CG2 . VAL A 1 744 ? 30.413 90.869 -29.213 1.00 15.43 ? 744 VAL A CG2 1 ATOM 5857 N N . VAL A 1 745 ? 31.009 86.812 -31.448 1.00 12.75 ? 745 VAL A N 1 ATOM 5858 C CA . VAL A 1 745 ? 31.658 85.574 -31.825 1.00 12.12 ? 745 VAL A CA 1 ATOM 5859 C C . VAL A 1 745 ? 32.949 85.827 -32.579 1.00 12.42 ? 745 VAL A C 1 ATOM 5860 O O . VAL A 1 745 ? 32.985 86.586 -33.555 1.00 12.85 ? 745 VAL A O 1 ATOM 5861 C CB . VAL A 1 745 ? 30.711 84.718 -32.712 1.00 11.48 ? 745 VAL A CB 1 ATOM 5862 C CG1 . VAL A 1 745 ? 31.415 83.441 -33.163 1.00 12.07 ? 745 VAL A CG1 1 ATOM 5863 C CG2 . VAL A 1 745 ? 29.438 84.381 -31.933 1.00 13.24 ? 745 VAL A CG2 1 ATOM 5864 N N . LEU A 1 746 ? 34.021 85.197 -32.118 1.00 11.49 ? 746 LEU A N 1 ATOM 5865 C CA . LEU A 1 746 ? 35.321 85.335 -32.764 1.00 10.95 ? 746 LEU A CA 1 ATOM 5866 C C . LEU A 1 746 ? 35.734 84.030 -33.452 1.00 12.11 ? 746 LEU A C 1 ATOM 5867 O O . LEU A 1 746 ? 35.831 82.970 -32.804 1.00 11.35 ? 746 LEU A O 1 ATOM 5868 C CB . LEU A 1 746 ? 36.375 85.700 -31.721 1.00 11.39 ? 746 LEU A CB 1 ATOM 5869 C CG . LEU A 1 746 ? 37.829 85.612 -32.191 1.00 12.39 ? 746 LEU A CG 1 ATOM 5870 C CD1 . LEU A 1 746 ? 38.078 86.691 -33.237 1.00 12.00 ? 746 LEU A CD1 1 ATOM 5871 C CD2 . LEU A 1 746 ? 38.779 85.794 -30.989 1.00 12.75 ? 746 LEU A CD2 1 ATOM 5872 N N . VAL A 1 747 ? 36.027 84.101 -34.739 1.00 11.63 ? 747 VAL A N 1 ATOM 5873 C CA . VAL A 1 747 ? 36.408 82.908 -35.464 1.00 12.23 ? 747 VAL A CA 1 ATOM 5874 C C . VAL A 1 747 ? 37.856 83.024 -35.924 1.00 13.85 ? 747 VAL A C 1 ATOM 5875 O O . VAL A 1 747 ? 38.224 83.977 -36.617 1.00 14.92 ? 747 VAL A O 1 ATOM 5876 C CB . VAL A 1 747 ? 35.468 82.722 -36.698 1.00 13.23 ? 747 VAL A CB 1 ATOM 5877 C CG1 . VAL A 1 747 ? 35.852 81.482 -37.495 1.00 13.64 ? 747 VAL A CG1 1 ATOM 5878 C CG2 . VAL A 1 747 ? 34.011 82.656 -36.246 1.00 11.20 ? 747 VAL A CG2 1 ATOM 5879 N N . THR A 1 748 ? 38.697 82.078 -35.534 1.00 13.59 ? 748 THR A N 1 ATOM 5880 C CA . THR A 1 748 ? 40.087 82.108 -35.978 1.00 14.41 ? 748 THR A CA 1 ATOM 5881 C C . THR A 1 748 ? 40.258 80.872 -36.826 1.00 14.99 ? 748 THR A C 1 ATOM 5882 O O . THR A 1 748 ? 39.915 79.782 -36.390 1.00 15.86 ? 748 THR A O 1 ATOM 5883 C CB . THR A 1 748 ? 41.062 82.095 -34.774 1.00 14.70 ? 748 THR A CB 1 ATOM 5884 O OG1 . THR A 1 748 ? 40.863 83.304 -34.024 1.00 15.20 ? 748 THR A OG1 1 ATOM 5885 C CG2 . THR A 1 748 ? 42.526 82.008 -35.249 1.00 14.70 ? 748 THR A CG2 1 ATOM 5886 N N . LYS A 1 749 ? 40.764 81.030 -38.041 1.00 15.43 ? 749 LYS A N 1 ATOM 5887 C CA . LYS A 1 749 ? 40.931 79.884 -38.911 1.00 16.34 ? 749 LYS A CA 1 ATOM 5888 C C . LYS A 1 749 ? 42.379 79.738 -39.317 1.00 15.39 ? 749 LYS A C 1 ATOM 5889 O O . LYS A 1 749 ? 42.971 80.636 -39.942 1.00 15.05 ? 749 LYS A O 1 ATOM 5890 C CB . LYS A 1 749 ? 40.036 80.012 -40.151 1.00 17.70 ? 749 LYS A CB 1 ATOM 5891 C CG . LYS A 1 749 ? 40.300 78.963 -41.208 1.00 21.23 ? 749 LYS A CG 1 ATOM 5892 C CD . LYS A 1 749 ? 39.231 79.018 -42.312 1.00 24.30 ? 749 LYS A CD 1 ATOM 5893 C CE . LYS A 1 749 ? 39.685 78.231 -43.525 1.00 25.72 ? 749 LYS A CE 1 ATOM 5894 N NZ . LYS A 1 749 ? 38.688 78.345 -44.631 1.00 30.38 ? 749 LYS A NZ 1 ATOM 5895 N N . GLY A 1 750 ? 42.941 78.588 -38.973 1.00 13.99 ? 750 GLY A N 1 ATOM 5896 C CA . GLY A 1 750 ? 44.340 78.352 -39.272 1.00 13.87 ? 750 GLY A CA 1 ATOM 5897 C C . GLY A 1 750 ? 44.507 76.998 -39.889 1.00 14.84 ? 750 GLY A C 1 ATOM 5898 O O . GLY A 1 750 ? 43.576 76.174 -39.901 1.00 14.29 ? 750 GLY A O 1 ATOM 5899 N N . LYS A 1 751 ? 45.692 76.759 -40.418 1.00 15.69 ? 751 LYS A N 1 ATOM 5900 C CA . LYS A 1 751 ? 45.972 75.486 -41.030 1.00 16.72 ? 751 LYS A CA 1 ATOM 5901 C C . LYS A 1 751 ? 46.181 74.386 -39.983 1.00 15.93 ? 751 LYS A C 1 ATOM 5902 O O . LYS A 1 751 ? 45.868 73.224 -40.221 1.00 15.27 ? 751 LYS A O 1 ATOM 5903 C CB . LYS A 1 751 ? 47.213 75.614 -41.908 1.00 20.45 ? 751 LYS A CB 1 ATOM 5904 C CG . LYS A 1 751 ? 47.559 74.333 -42.614 1.00 25.65 ? 751 LYS A CG 1 ATOM 5905 C CD . LYS A 1 751 ? 48.517 74.574 -43.793 1.00 30.44 ? 751 LYS A CD 1 ATOM 5906 C CE . LYS A 1 751 ? 49.086 73.243 -44.271 1.00 32.98 ? 751 LYS A CE 1 ATOM 5907 N NZ . LYS A 1 751 ? 47.987 72.229 -44.459 1.00 35.48 ? 751 LYS A NZ 1 ATOM 5908 N N . LEU A 1 752 ? 46.714 74.743 -38.825 1.00 14.25 ? 752 LEU A N 1 ATOM 5909 C CA . LEU A 1 752 ? 46.947 73.739 -37.784 1.00 14.79 ? 752 LEU A CA 1 ATOM 5910 C C . LEU A 1 752 ? 45.865 73.762 -36.713 1.00 14.90 ? 752 LEU A C 1 ATOM 5911 O O . LEU A 1 752 ? 45.535 72.730 -36.129 1.00 15.39 ? 752 LEU A O 1 ATOM 5912 C CB . LEU A 1 752 ? 48.306 73.977 -37.120 1.00 14.53 ? 752 LEU A CB 1 ATOM 5913 C CG . LEU A 1 752 ? 49.517 73.983 -38.067 1.00 15.87 ? 752 LEU A CG 1 ATOM 5914 C CD1 . LEU A 1 752 ? 50.793 74.085 -37.248 1.00 16.43 ? 752 LEU A CD1 1 ATOM 5915 C CD2 . LEU A 1 752 ? 49.524 72.727 -38.905 1.00 16.78 ? 752 LEU A CD2 1 ATOM 5916 N N . GLU A 1 753 ? 45.301 74.946 -36.482 1.00 13.57 ? 753 GLU A N 1 ATOM 5917 C CA . GLU A 1 753 ? 44.297 75.125 -35.455 1.00 13.01 ? 753 GLU A CA 1 ATOM 5918 C C . GLU A 1 753 ? 43.293 76.241 -35.781 1.00 13.02 ? 753 GLU A C 1 ATOM 5919 O O . GLU A 1 753 ? 43.668 77.365 -36.130 1.00 12.66 ? 753 GLU A O 1 ATOM 5920 C CB . GLU A 1 753 ? 44.995 75.463 -34.124 1.00 11.94 ? 753 GLU A CB 1 ATOM 5921 C CG . GLU A 1 753 ? 44.061 75.637 -32.949 1.00 15.38 ? 753 GLU A CG 1 ATOM 5922 C CD . GLU A 1 753 ? 44.777 76.092 -31.658 1.00 17.98 ? 753 GLU A CD 1 ATOM 5923 O OE1 . GLU A 1 753 ? 45.033 77.304 -31.486 1.00 19.78 ? 753 GLU A OE1 1 ATOM 5924 O OE2 . GLU A 1 753 ? 45.075 75.221 -30.817 1.00 19.55 ? 753 GLU A OE2 1 ATOM 5925 N N . SER A 1 754 ? 42.018 75.922 -35.643 1.00 12.40 ? 754 SER A N 1 ATOM 5926 C CA . SER A 1 754 ? 40.973 76.907 -35.843 1.00 11.89 ? 754 SER A CA 1 ATOM 5927 C C . SER A 1 754 ? 40.145 76.864 -34.565 1.00 12.34 ? 754 SER A C 1 ATOM 5928 O O . SER A 1 754 ? 40.246 75.907 -33.782 1.00 12.61 ? 754 SER A O 1 ATOM 5929 C CB . SER A 1 754 ? 40.119 76.519 -37.034 1.00 11.52 ? 754 SER A CB 1 ATOM 5930 O OG . SER A 1 754 ? 40.920 76.486 -38.206 1.00 13.08 ? 754 SER A OG 1 ATOM 5931 N N . SER A 1 755 ? 39.335 77.884 -34.334 1.00 11.42 ? 755 SER A N 1 ATOM 5932 C CA . SER A 1 755 ? 38.489 77.872 -33.166 1.00 11.44 ? 755 SER A CA 1 ATOM 5933 C C . SER A 1 755 ? 37.348 78.876 -33.312 1.00 11.08 ? 755 SER A C 1 ATOM 5934 O O . SER A 1 755 ? 37.387 79.786 -34.166 1.00 11.31 ? 755 SER A O 1 ATOM 5935 C CB . SER A 1 755 ? 39.313 78.197 -31.908 1.00 13.54 ? 755 SER A CB 1 ATOM 5936 O OG . SER A 1 755 ? 39.636 79.551 -31.867 1.00 13.40 ? 755 SER A OG 1 ATOM 5937 N N . VAL A 1 756 ? 36.312 78.679 -32.517 1.00 9.77 ? 756 VAL A N 1 ATOM 5938 C CA . VAL A 1 756 ? 35.185 79.601 -32.489 1.00 10.93 ? 756 VAL A CA 1 ATOM 5939 C C . VAL A 1 756 ? 34.984 79.887 -31.006 1.00 11.88 ? 756 VAL A C 1 ATOM 5940 O O . VAL A 1 756 ? 34.783 78.951 -30.209 1.00 11.68 ? 756 VAL A O 1 ATOM 5941 C CB . VAL A 1 756 ? 33.892 78.974 -33.035 1.00 10.78 ? 756 VAL A CB 1 ATOM 5942 C CG1 . VAL A 1 756 ? 32.694 79.939 -32.808 1.00 8.71 ? 756 VAL A CG1 1 ATOM 5943 C CG2 . VAL A 1 756 ? 34.070 78.611 -34.502 1.00 9.40 ? 756 VAL A CG2 1 ATOM 5944 N N . SER A 1 757 ? 35.034 81.167 -30.654 1.00 11.46 ? 757 SER A N 1 ATOM 5945 C CA . SER A 1 757 ? 34.869 81.605 -29.268 1.00 11.81 ? 757 SER A CA 1 ATOM 5946 C C . SER A 1 757 ? 33.734 82.599 -29.156 1.00 11.38 ? 757 SER A C 1 ATOM 5947 O O . SER A 1 757 ? 33.581 83.446 -30.023 1.00 11.05 ? 757 SER A O 1 ATOM 5948 C CB . SER A 1 757 ? 36.156 82.279 -28.770 1.00 11.92 ? 757 SER A CB 1 ATOM 5949 O OG . SER A 1 757 ? 37.272 81.416 -28.993 1.00 16.34 ? 757 SER A OG 1 ATOM 5950 N N . VAL A 1 758 ? 32.944 82.510 -28.098 1.00 11.87 ? 758 VAL A N 1 ATOM 5951 C CA . VAL A 1 758 ? 31.849 83.463 -27.924 1.00 11.65 ? 758 VAL A CA 1 ATOM 5952 C C . VAL A 1 758 ? 31.729 83.870 -26.457 1.00 13.00 ? 758 VAL A C 1 ATOM 5953 O O . VAL A 1 758 ? 31.925 83.038 -25.544 1.00 11.72 ? 758 VAL A O 1 ATOM 5954 C CB . VAL A 1 758 ? 30.525 82.872 -28.454 1.00 12.10 ? 758 VAL A CB 1 ATOM 5955 C CG1 . VAL A 1 758 ? 30.245 81.498 -27.819 1.00 10.09 ? 758 VAL A CG1 1 ATOM 5956 C CG2 . VAL A 1 758 ? 29.385 83.850 -28.211 1.00 10.88 ? 758 VAL A CG2 1 ATOM 5957 N N . GLY A 1 759 ? 31.476 85.163 -26.248 1.00 12.58 ? 759 GLY A N 1 ATOM 5958 C CA . GLY A 1 759 ? 31.328 85.736 -24.927 1.00 12.46 ? 759 GLY A CA 1 ATOM 5959 C C . GLY A 1 759 ? 29.865 85.700 -24.508 1.00 14.09 ? 759 GLY A C 1 ATOM 5960 O O . GLY A 1 759 ? 29.041 86.549 -24.893 1.00 13.40 ? 759 GLY A O 1 ATOM 5961 N N . LEU A 1 760 ? 29.534 84.688 -23.729 1.00 13.74 ? 760 LEU A N 1 ATOM 5962 C CA . LEU A 1 760 ? 28.184 84.500 -23.228 1.00 14.93 ? 760 LEU A CA 1 ATOM 5963 C C . LEU A 1 760 ? 28.139 84.984 -21.803 1.00 14.65 ? 760 LEU A C 1 ATOM 5964 O O . LEU A 1 760 ? 29.183 85.187 -21.178 1.00 16.30 ? 760 LEU A O 1 ATOM 5965 C CB . LEU A 1 760 ? 27.821 83.004 -23.260 1.00 15.27 ? 760 LEU A CB 1 ATOM 5966 C CG . LEU A 1 760 ? 27.985 82.282 -24.591 1.00 15.70 ? 760 LEU A CG 1 ATOM 5967 C CD1 . LEU A 1 760 ? 27.752 80.784 -24.437 1.00 15.70 ? 760 LEU A CD1 1 ATOM 5968 C CD2 . LEU A 1 760 ? 26.981 82.872 -25.567 1.00 16.68 ? 760 LEU A CD2 1 ATOM 5969 N N . PRO A 1 761 ? 26.933 85.186 -21.252 1.00 16.31 ? 761 PRO A N 1 ATOM 5970 C CA . PRO A 1 761 ? 26.846 85.645 -19.853 1.00 17.54 ? 761 PRO A CA 1 ATOM 5971 C C . PRO A 1 761 ? 27.415 84.541 -18.968 1.00 17.82 ? 761 PRO A C 1 ATOM 5972 O O . PRO A 1 761 ? 26.946 83.389 -19.014 1.00 17.17 ? 761 PRO A O 1 ATOM 5973 C CB . PRO A 1 761 ? 25.333 85.832 -19.632 1.00 18.65 ? 761 PRO A CB 1 ATOM 5974 C CG . PRO A 1 761 ? 24.852 86.198 -21.015 1.00 18.49 ? 761 PRO A CG 1 ATOM 5975 C CD . PRO A 1 761 ? 25.614 85.224 -21.903 1.00 16.59 ? 761 PRO A CD 1 ATOM 5976 N N . SER A 1 762 ? 28.437 84.897 -18.206 1.00 17.07 ? 762 SER A N 1 ATOM 5977 C CA . SER A 1 762 ? 29.110 83.987 -17.282 1.00 17.42 ? 762 SER A CA 1 ATOM 5978 C C . SER A 1 762 ? 30.093 83.007 -17.897 1.00 16.61 ? 762 SER A C 1 ATOM 5979 O O . SER A 1 762 ? 30.799 82.309 -17.156 1.00 16.76 ? 762 SER A O 1 ATOM 5980 C CB . SER A 1 762 ? 28.097 83.168 -16.488 1.00 17.59 ? 762 SER A CB 1 ATOM 5981 O OG . SER A 1 762 ? 27.376 83.968 -15.587 1.00 19.54 ? 762 SER A OG 1 ATOM 5982 N N . VAL A 1 763 ? 30.137 82.935 -19.224 1.00 15.17 ? 763 VAL A N 1 ATOM 5983 C CA . VAL A 1 763 ? 31.022 81.970 -19.875 1.00 14.22 ? 763 VAL A CA 1 ATOM 5984 C C . VAL A 1 763 ? 31.599 82.380 -21.231 1.00 13.50 ? 763 VAL A C 1 ATOM 5985 O O . VAL A 1 763 ? 30.846 82.763 -22.124 1.00 14.07 ? 763 VAL A O 1 ATOM 5986 C CB . VAL A 1 763 ? 30.281 80.625 -20.164 1.00 14.16 ? 763 VAL A CB 1 ATOM 5987 C CG1 . VAL A 1 763 ? 31.269 79.607 -20.750 1.00 13.30 ? 763 VAL A CG1 1 ATOM 5988 C CG2 . VAL A 1 763 ? 29.600 80.097 -18.909 1.00 13.08 ? 763 VAL A CG2 1 ATOM 5989 N N . VAL A 1 764 ? 32.921 82.316 -21.388 1.00 11.99 ? 764 VAL A N 1 ATOM 5990 C CA . VAL A 1 764 ? 33.503 82.551 -22.693 1.00 11.93 ? 764 VAL A CA 1 ATOM 5991 C C . VAL A 1 764 ? 33.676 81.088 -23.100 1.00 12.37 ? 764 VAL A C 1 ATOM 5992 O O . VAL A 1 764 ? 34.489 80.366 -22.514 1.00 12.08 ? 764 VAL A O 1 ATOM 5993 C CB . VAL A 1 764 ? 34.882 83.244 -22.674 1.00 13.07 ? 764 VAL A CB 1 ATOM 5994 C CG1 . VAL A 1 764 ? 35.443 83.252 -24.098 1.00 12.11 ? 764 VAL A CG1 1 ATOM 5995 C CG2 . VAL A 1 764 ? 34.735 84.701 -22.139 1.00 10.55 ? 764 VAL A CG2 1 ATOM 5996 N N . HIS A 1 765 ? 32.876 80.672 -24.084 1.00 11.90 ? 765 HIS A N 1 ATOM 5997 C CA . HIS A 1 765 ? 32.805 79.294 -24.581 1.00 12.13 ? 765 HIS A CA 1 ATOM 5998 C C . HIS A 1 765 ? 33.668 79.188 -25.816 1.00 13.31 ? 765 HIS A C 1 ATOM 5999 O O . HIS A 1 765 ? 33.524 80.005 -26.729 1.00 13.21 ? 765 HIS A O 1 ATOM 6000 C CB . HIS A 1 765 ? 31.330 78.990 -24.905 1.00 10.65 ? 765 HIS A CB 1 ATOM 6001 C CG . HIS A 1 765 ? 31.099 77.654 -25.527 1.00 9.72 ? 765 HIS A CG 1 ATOM 6002 N ND1 . HIS A 1 765 ? 31.376 76.469 -24.878 1.00 7.85 ? 765 HIS A ND1 1 ATOM 6003 C CD2 . HIS A 1 765 ? 30.600 77.315 -26.742 1.00 8.45 ? 765 HIS A CD2 1 ATOM 6004 C CE1 . HIS A 1 765 ? 31.062 75.454 -25.666 1.00 8.03 ? 765 HIS A CE1 1 ATOM 6005 N NE2 . HIS A 1 765 ? 30.585 75.940 -26.802 1.00 10.79 ? 765 HIS A NE2 1 ATOM 6006 N N . GLN A 1 766 ? 34.547 78.191 -25.874 1.00 12.63 ? 766 GLN A N 1 ATOM 6007 C CA . GLN A 1 766 ? 35.451 78.101 -27.017 1.00 13.75 ? 766 GLN A CA 1 ATOM 6008 C C . GLN A 1 766 ? 35.543 76.709 -27.559 1.00 12.20 ? 766 GLN A C 1 ATOM 6009 O O . GLN A 1 766 ? 35.766 75.788 -26.786 1.00 11.62 ? 766 GLN A O 1 ATOM 6010 C CB . GLN A 1 766 ? 36.882 78.536 -26.623 1.00 15.36 ? 766 GLN A CB 1 ATOM 6011 C CG . GLN A 1 766 ? 36.940 79.827 -25.745 1.00 19.70 ? 766 GLN A CG 1 ATOM 6012 C CD . GLN A 1 766 ? 38.014 79.766 -24.611 1.00 24.85 ? 766 GLN A CD 1 ATOM 6013 O OE1 . GLN A 1 766 ? 39.221 79.550 -24.889 1.00 25.37 ? 766 GLN A OE1 1 ATOM 6014 N NE2 . GLN A 1 766 ? 37.569 79.946 -23.331 1.00 20.80 ? 766 GLN A NE2 1 ATOM 6015 N N . THR A 1 767 ? 35.385 76.561 -28.881 1.00 10.96 ? 767 THR A N 1 ATOM 6016 C CA . THR A 1 767 ? 35.509 75.269 -29.531 1.00 11.01 ? 767 THR A CA 1 ATOM 6017 C C . THR A 1 767 ? 36.768 75.312 -30.392 1.00 11.95 ? 767 THR A C 1 ATOM 6018 O O . THR A 1 767 ? 36.877 76.107 -31.337 1.00 9.96 ? 767 THR A O 1 ATOM 6019 C CB . THR A 1 767 ? 34.280 74.933 -30.392 1.00 12.06 ? 767 THR A CB 1 ATOM 6020 O OG1 . THR A 1 767 ? 33.116 74.970 -29.556 1.00 12.70 ? 767 THR A OG1 1 ATOM 6021 C CG2 . THR A 1 767 ? 34.421 73.527 -31.013 1.00 11.65 ? 767 THR A CG2 1 ATOM 6022 N N . ILE A 1 768 ? 37.730 74.452 -30.053 1.00 9.98 ? 768 ILE A N 1 ATOM 6023 C CA . ILE A 1 768 ? 39.001 74.436 -30.763 1.00 11.67 ? 768 ILE A CA 1 ATOM 6024 C C . ILE A 1 768 ? 39.176 73.192 -31.584 1.00 11.21 ? 768 ILE A C 1 ATOM 6025 O O . ILE A 1 768 ? 38.927 72.073 -31.107 1.00 11.46 ? 768 ILE A O 1 ATOM 6026 C CB . ILE A 1 768 ? 40.168 74.558 -29.760 1.00 12.96 ? 768 ILE A CB 1 ATOM 6027 C CG1 . ILE A 1 768 ? 39.950 75.787 -28.867 1.00 14.46 ? 768 ILE A CG1 1 ATOM 6028 C CG2 . ILE A 1 768 ? 41.467 74.708 -30.495 1.00 15.46 ? 768 ILE A CG2 1 ATOM 6029 C CD1 . ILE A 1 768 ? 40.778 75.764 -27.594 1.00 16.37 ? 768 ILE A CD1 1 ATOM 6030 N N . MET A 1 769 ? 39.643 73.381 -32.806 1.00 11.25 ? 769 MET A N 1 ATOM 6031 C CA . MET A 1 769 ? 39.850 72.280 -33.736 1.00 13.35 ? 769 MET A CA 1 ATOM 6032 C C . MET A 1 769 ? 41.288 72.154 -34.221 1.00 13.14 ? 769 MET A C 1 ATOM 6033 O O . MET A 1 769 ? 41.878 73.125 -34.714 1.00 13.71 ? 769 MET A O 1 ATOM 6034 C CB . MET A 1 769 ? 38.940 72.474 -34.948 1.00 13.60 ? 769 MET A CB 1 ATOM 6035 C CG . MET A 1 769 ? 37.464 72.417 -34.594 1.00 17.26 ? 769 MET A CG 1 ATOM 6036 S SD . MET A 1 769 ? 36.422 73.123 -35.902 1.00 19.49 ? 769 MET A SD 1 ATOM 6037 C CE . MET A 1 769 ? 36.521 74.767 -35.439 1.00 22.56 ? 769 MET A CE 1 ATOM 6038 N N . ARG A 1 770 ? 41.829 70.947 -34.122 1.00 12.76 ? 770 ARG A N 1 ATOM 6039 C CA . ARG A 1 770 ? 43.193 70.699 -34.552 1.00 14.31 ? 770 ARG A CA 1 ATOM 6040 C C . ARG A 1 770 ? 43.281 69.488 -35.472 1.00 14.45 ? 770 ARG A C 1 ATOM 6041 O O . ARG A 1 770 ? 44.366 68.980 -35.737 1.00 14.60 ? 770 ARG A O 1 ATOM 6042 C CB . ARG A 1 770 ? 44.077 70.478 -33.336 1.00 14.68 ? 770 ARG A CB 1 ATOM 6043 C CG . ARG A 1 770 ? 44.076 71.647 -32.336 1.00 18.48 ? 770 ARG A CG 1 ATOM 6044 C CD . ARG A 1 770 ? 45.112 71.424 -31.275 1.00 20.43 ? 770 ARG A CD 1 ATOM 6045 N NE . ARG A 1 770 ? 45.151 72.467 -30.260 1.00 25.02 ? 770 ARG A NE 1 ATOM 6046 C CZ . ARG A 1 770 ? 44.379 72.504 -29.178 1.00 27.12 ? 770 ARG A CZ 1 ATOM 6047 N NH1 . ARG A 1 770 ? 43.478 71.555 -28.953 1.00 28.88 ? 770 ARG A NH1 1 ATOM 6048 N NH2 . ARG A 1 770 ? 44.535 73.476 -28.287 1.00 30.58 ? 770 ARG A NH2 1 ATOM 6049 N N . GLY A 1 771 ? 42.141 69.014 -35.944 1.00 15.15 ? 771 GLY A N 1 ATOM 6050 C CA . GLY A 1 771 ? 42.190 67.870 -36.827 1.00 18.33 ? 771 GLY A CA 1 ATOM 6051 C C . GLY A 1 771 ? 41.454 66.644 -36.349 1.00 19.13 ? 771 GLY A C 1 ATOM 6052 O O . GLY A 1 771 ? 41.206 65.734 -37.157 1.00 21.43 ? 771 GLY A O 1 ATOM 6053 N N . GLY A 1 772 ? 41.134 66.588 -35.054 1.00 18.33 ? 772 GLY A N 1 ATOM 6054 C CA . GLY A 1 772 ? 40.403 65.446 -34.536 1.00 17.28 ? 772 GLY A CA 1 ATOM 6055 C C . GLY A 1 772 ? 39.222 65.929 -33.705 1.00 15.92 ? 772 GLY A C 1 ATOM 6056 O O . GLY A 1 772 ? 38.642 66.995 -33.966 1.00 15.63 ? 772 GLY A O 1 ATOM 6057 N N . ALA A 1 773 ? 38.864 65.156 -32.704 1.00 14.27 ? 773 ALA A N 1 ATOM 6058 C CA . ALA A 1 773 ? 37.767 65.549 -31.844 1.00 13.08 ? 773 ALA A CA 1 ATOM 6059 C C . ALA A 1 773 ? 38.132 66.949 -31.343 1.00 12.89 ? 773 ALA A C 1 ATOM 6060 O O . ALA A 1 773 ? 39.269 67.214 -30.949 1.00 13.16 ? 773 ALA A O 1 ATOM 6061 C CB . ALA A 1 773 ? 37.643 64.599 -30.675 1.00 12.55 ? 773 ALA A CB 1 ATOM 6062 N N . PRO A 1 774 ? 37.170 67.855 -31.354 1.00 11.68 ? 774 PRO A N 1 ATOM 6063 C CA . PRO A 1 774 ? 37.470 69.214 -30.891 1.00 11.67 ? 774 PRO A CA 1 ATOM 6064 C C . PRO A 1 774 ? 37.697 69.265 -29.365 1.00 12.21 ? 774 PRO A C 1 ATOM 6065 O O . PRO A 1 774 ? 37.286 68.357 -28.621 1.00 11.84 ? 774 PRO A O 1 ATOM 6066 C CB . PRO A 1 774 ? 36.218 69.993 -31.294 1.00 12.63 ? 774 PRO A CB 1 ATOM 6067 C CG . PRO A 1 774 ? 35.115 68.966 -31.207 1.00 13.10 ? 774 PRO A CG 1 ATOM 6068 C CD . PRO A 1 774 ? 35.781 67.733 -31.842 1.00 11.35 ? 774 PRO A CD 1 ATOM 6069 N N . GLU A 1 775 ? 38.362 70.325 -28.926 1.00 11.94 ? 775 GLU A N 1 ATOM 6070 C CA . GLU A 1 775 ? 38.586 70.575 -27.519 1.00 12.22 ? 775 GLU A CA 1 ATOM 6071 C C . GLU A 1 775 ? 37.628 71.706 -27.176 1.00 12.31 ? 775 GLU A C 1 ATOM 6072 O O . GLU A 1 775 ? 37.419 72.632 -27.960 1.00 11.50 ? 775 GLU A O 1 ATOM 6073 C CB . GLU A 1 775 ? 40.025 71.015 -27.235 1.00 13.41 ? 775 GLU A CB 1 ATOM 6074 C CG . GLU A 1 775 ? 40.253 71.510 -25.768 1.00 17.44 ? 775 GLU A CG 1 ATOM 6075 C CD . GLU A 1 775 ? 41.668 72.052 -25.496 1.00 18.96 ? 775 GLU A CD 1 ATOM 6076 O OE1 . GLU A 1 775 ? 42.550 71.855 -26.331 1.00 23.15 ? 775 GLU A OE1 1 ATOM 6077 O OE2 . GLU A 1 775 ? 41.903 72.666 -24.432 1.00 20.14 ? 775 GLU A OE2 1 ATOM 6078 N N . ILE A 1 776 ? 37.016 71.629 -26.012 1.00 11.63 ? 776 ILE A N 1 ATOM 6079 C CA . ILE A 1 776 ? 36.097 72.688 -25.613 1.00 11.49 ? 776 ILE A CA 1 ATOM 6080 C C . ILE A 1 776 ? 36.707 73.326 -24.370 1.00 11.15 ? 776 ILE A C 1 ATOM 6081 O O . ILE A 1 776 ? 37.181 72.612 -23.481 1.00 11.02 ? 776 ILE A O 1 ATOM 6082 C CB . ILE A 1 776 ? 34.732 72.128 -25.203 1.00 11.62 ? 776 ILE A CB 1 ATOM 6083 C CG1 . ILE A 1 776 ? 34.180 71.195 -26.295 1.00 13.03 ? 776 ILE A CG1 1 ATOM 6084 C CG2 . ILE A 1 776 ? 33.785 73.289 -24.827 1.00 11.27 ? 776 ILE A CG2 1 ATOM 6085 C CD1 . ILE A 1 776 ? 33.933 71.880 -27.646 1.00 12.86 ? 776 ILE A CD1 1 ATOM 6086 N N . ARG A 1 777 ? 36.725 74.653 -24.308 1.00 10.40 ? 777 ARG A N 1 ATOM 6087 C CA . ARG A 1 777 ? 37.209 75.338 -23.100 1.00 9.57 ? 777 ARG A CA 1 ATOM 6088 C C . ARG A 1 777 ? 36.147 76.348 -22.672 1.00 10.91 ? 777 ARG A C 1 ATOM 6089 O O . ARG A 1 777 ? 35.597 77.115 -23.509 1.00 9.85 ? 777 ARG A O 1 ATOM 6090 C CB . ARG A 1 777 ? 38.545 76.072 -23.361 1.00 11.97 ? 777 ARG A CB 1 ATOM 6091 C CG . ARG A 1 777 ? 39.700 75.177 -23.810 1.00 11.49 ? 777 ARG A CG 1 ATOM 6092 C CD . ARG A 1 777 ? 41.035 75.947 -23.803 1.00 14.43 ? 777 ARG A CD 1 ATOM 6093 N NE . ARG A 1 777 ? 42.104 75.128 -24.374 1.00 14.15 ? 777 ARG A NE 1 ATOM 6094 C CZ . ARG A 1 777 ? 43.248 75.599 -24.871 1.00 16.92 ? 777 ARG A CZ 1 ATOM 6095 N NH1 . ARG A 1 777 ? 43.503 76.912 -24.864 1.00 16.15 ? 777 ARG A NH1 1 ATOM 6096 N NH2 . ARG A 1 777 ? 44.117 74.760 -25.437 1.00 15.84 ? 777 ARG A NH2 1 ATOM 6097 N N . ASN A 1 778 ? 35.814 76.333 -21.387 1.00 8.85 ? 778 ASN A N 1 ATOM 6098 C CA . ASN A 1 778 ? 34.868 77.292 -20.862 1.00 8.99 ? 778 ASN A CA 1 ATOM 6099 C C . ASN A 1 778 ? 35.540 78.151 -19.794 1.00 9.38 ? 778 ASN A C 1 ATOM 6100 O O . ASN A 1 778 ? 35.973 77.619 -18.745 1.00 8.21 ? 778 ASN A O 1 ATOM 6101 C CB . ASN A 1 778 ? 33.668 76.617 -20.165 1.00 9.18 ? 778 ASN A CB 1 ATOM 6102 C CG . ASN A 1 778 ? 32.707 75.955 -21.134 1.00 10.43 ? 778 ASN A CG 1 ATOM 6103 O OD1 . ASN A 1 778 ? 32.633 76.318 -22.328 1.00 8.53 ? 778 ASN A OD1 1 ATOM 6104 N ND2 . ASN A 1 778 ? 31.937 74.994 -20.616 1.00 9.55 ? 778 ASN A ND2 1 ATOM 6105 N N . LEU A 1 779 ? 35.611 79.457 -20.027 1.00 8.79 ? 779 LEU A N 1 ATOM 6106 C CA . LEU A 1 779 ? 36.147 80.348 -19.001 1.00 9.84 ? 779 LEU A CA 1 ATOM 6107 C C . LEU A 1 779 ? 34.893 80.755 -18.208 1.00 9.16 ? 779 LEU A C 1 ATOM 6108 O O . LEU A 1 779 ? 34.119 81.625 -18.621 1.00 9.42 ? 779 LEU A O 1 ATOM 6109 C CB . LEU A 1 779 ? 36.837 81.559 -19.638 1.00 10.28 ? 779 LEU A CB 1 ATOM 6110 C CG . LEU A 1 779 ? 37.357 82.642 -18.672 1.00 13.42 ? 779 LEU A CG 1 ATOM 6111 C CD1 . LEU A 1 779 ? 38.328 82.038 -17.644 1.00 14.59 ? 779 LEU A CD1 1 ATOM 6112 C CD2 . LEU A 1 779 ? 38.071 83.748 -19.484 1.00 14.78 ? 779 LEU A CD2 1 ATOM 6113 N N . VAL A 1 780 ? 34.689 80.100 -17.073 1.00 9.91 ? 780 VAL A N 1 ATOM 6114 C CA . VAL A 1 780 ? 33.512 80.325 -16.250 1.00 9.63 ? 780 VAL A CA 1 ATOM 6115 C C . VAL A 1 780 ? 33.665 81.337 -15.107 1.00 11.13 ? 780 VAL A C 1 ATOM 6116 O O . VAL A 1 780 ? 34.470 81.154 -14.206 1.00 11.25 ? 780 VAL A O 1 ATOM 6117 C CB . VAL A 1 780 ? 32.982 78.963 -15.659 1.00 9.15 ? 780 VAL A CB 1 ATOM 6118 C CG1 . VAL A 1 780 ? 31.679 79.187 -14.887 1.00 7.14 ? 780 VAL A CG1 1 ATOM 6119 C CG2 . VAL A 1 780 ? 32.773 77.949 -16.791 1.00 6.73 ? 780 VAL A CG2 1 ATOM 6120 N N . ASP A 1 781 ? 32.876 82.410 -15.178 1.00 10.42 ? 781 ASP A N 1 ATOM 6121 C CA . ASP A 1 781 ? 32.860 83.445 -14.143 1.00 11.95 ? 781 ASP A CA 1 ATOM 6122 C C . ASP A 1 781 ? 31.400 83.705 -13.803 1.00 11.39 ? 781 ASP A C 1 ATOM 6123 O O . ASP A 1 781 ? 30.737 84.532 -14.437 1.00 10.67 ? 781 ASP A O 1 ATOM 6124 C CB . ASP A 1 781 ? 33.500 84.735 -14.655 1.00 12.58 ? 781 ASP A CB 1 ATOM 6125 C CG . ASP A 1 781 ? 33.620 85.811 -13.567 1.00 13.83 ? 781 ASP A CG 1 ATOM 6126 O OD1 . ASP A 1 781 ? 34.056 86.924 -13.904 1.00 16.08 ? 781 ASP A OD1 1 ATOM 6127 O OD2 . ASP A 1 781 ? 33.293 85.558 -12.396 1.00 14.07 ? 781 ASP A OD2 1 ATOM 6128 N N . ILE A 1 782 ? 30.907 82.973 -12.822 1.00 11.43 ? 782 ILE A N 1 ATOM 6129 C CA . ILE A 1 782 ? 29.521 83.081 -12.373 1.00 14.07 ? 782 ILE A CA 1 ATOM 6130 C C . ILE A 1 782 ? 29.290 84.423 -11.631 1.00 17.26 ? 782 ILE A C 1 ATOM 6131 O O . ILE A 1 782 ? 28.188 84.711 -11.162 1.00 18.07 ? 782 ILE A O 1 ATOM 6132 C CB . ILE A 1 782 ? 29.209 81.885 -11.449 1.00 14.46 ? 782 ILE A CB 1 ATOM 6133 C CG1 . ILE A 1 782 ? 27.707 81.677 -11.294 1.00 15.12 ? 782 ILE A CG1 1 ATOM 6134 C CG2 . ILE A 1 782 ? 29.878 82.106 -10.098 1.00 14.43 ? 782 ILE A CG2 1 ATOM 6135 C CD1 . ILE A 1 782 ? 27.385 80.275 -10.696 1.00 11.21 ? 782 ILE A CD1 1 ATOM 6136 N N . GLY A 1 783 ? 30.349 85.218 -11.515 1.00 18.93 ? 783 GLY A N 1 ATOM 6137 C CA . GLY A 1 783 ? 30.247 86.545 -10.922 1.00 21.69 ? 783 GLY A CA 1 ATOM 6138 C C . GLY A 1 783 ? 29.390 86.646 -9.689 1.00 22.71 ? 783 GLY A C 1 ATOM 6139 O O . GLY A 1 783 ? 29.617 85.925 -8.715 1.00 22.93 ? 783 GLY A O 1 ATOM 6140 N N . SER A 1 784 ? 28.394 87.518 -9.714 1.00 24.23 ? 784 SER A N 1 ATOM 6141 C CA . SER A 1 784 ? 27.548 87.638 -8.529 1.00 27.20 ? 784 SER A CA 1 ATOM 6142 C C . SER A 1 784 ? 26.114 87.103 -8.707 1.00 27.89 ? 784 SER A C 1 ATOM 6143 O O . SER A 1 784 ? 25.194 87.496 -7.969 1.00 28.37 ? 784 SER A O 1 ATOM 6144 C CB . SER A 1 784 ? 27.521 89.090 -8.037 1.00 28.23 ? 784 SER A CB 1 ATOM 6145 O OG . SER A 1 784 ? 26.711 89.885 -8.890 1.00 30.79 ? 784 SER A OG 1 ATOM 6146 N N . LEU A 1 785 ? 25.920 86.190 -9.660 1.00 26.81 ? 785 LEU A N 1 ATOM 6147 C CA . LEU A 1 785 ? 24.596 85.620 -9.871 1.00 26.29 ? 785 LEU A CA 1 ATOM 6148 C C . LEU A 1 785 ? 24.299 84.673 -8.721 1.00 26.09 ? 785 LEU A C 1 ATOM 6149 O O . LEU A 1 785 ? 24.551 83.469 -8.816 1.00 27.09 ? 785 LEU A O 1 ATOM 6150 C CB . LEU A 1 785 ? 24.549 84.836 -11.186 1.00 25.26 ? 785 LEU A CB 1 ATOM 6151 C CG . LEU A 1 785 ? 24.854 85.580 -12.494 1.00 25.45 ? 785 LEU A CG 1 ATOM 6152 C CD1 . LEU A 1 785 ? 24.960 84.574 -13.608 1.00 23.27 ? 785 LEU A CD1 1 ATOM 6153 C CD2 . LEU A 1 785 ? 23.776 86.625 -12.798 1.00 24.80 ? 785 LEU A CD2 1 ATOM 6154 N N . ASP A 1 786 ? 23.745 85.191 -7.638 1.00 25.02 ? 786 ASP A N 1 ATOM 6155 C CA . ASP A 1 786 ? 23.436 84.331 -6.498 1.00 23.83 ? 786 ASP A CA 1 ATOM 6156 C C . ASP A 1 786 ? 22.382 83.256 -6.769 1.00 21.51 ? 786 ASP A C 1 ATOM 6157 O O . ASP A 1 786 ? 21.516 83.397 -7.643 1.00 19.45 ? 786 ASP A O 1 ATOM 6158 C CB . ASP A 1 786 ? 23.008 85.169 -5.298 1.00 25.95 ? 786 ASP A CB 1 ATOM 6159 C CG . ASP A 1 786 ? 24.188 85.812 -4.585 1.00 28.48 ? 786 ASP A CG 1 ATOM 6160 O OD1 . ASP A 1 786 ? 25.331 85.819 -5.124 1.00 29.49 ? 786 ASP A OD1 1 ATOM 6161 O OD2 . ASP A 1 786 ? 23.955 86.310 -3.467 1.00 30.09 ? 786 ASP A OD2 1 ATOM 6162 N N . ASN A 1 787 ? 22.499 82.167 -6.018 1.00 18.98 ? 787 ASN A N 1 ATOM 6163 C CA . ASN A 1 787 ? 21.582 81.042 -6.133 1.00 18.71 ? 787 ASN A CA 1 ATOM 6164 C C . ASN A 1 787 ? 21.360 80.628 -7.564 1.00 16.74 ? 787 ASN A C 1 ATOM 6165 O O . ASN A 1 787 ? 20.232 80.480 -8.016 1.00 15.57 ? 787 ASN A O 1 ATOM 6166 C CB . ASN A 1 787 ? 20.251 81.390 -5.468 1.00 18.45 ? 787 ASN A CB 1 ATOM 6167 C CG . ASN A 1 787 ? 20.415 81.605 -3.983 1.00 21.65 ? 787 ASN A CG 1 ATOM 6168 O OD1 . ASN A 1 787 ? 21.032 80.782 -3.293 1.00 21.92 ? 787 ASN A OD1 1 ATOM 6169 N ND2 . ASN A 1 787 ? 19.888 82.713 -3.480 1.00 22.06 ? 787 ASN A ND2 1 ATOM 6170 N N . THR A 1 788 ? 22.459 80.432 -8.265 1.00 14.71 ? 788 THR A N 1 ATOM 6171 C CA . THR A 1 788 ? 22.413 80.024 -9.652 1.00 14.26 ? 788 THR A CA 1 ATOM 6172 C C . THR A 1 788 ? 23.421 78.884 -9.875 1.00 13.11 ? 788 THR A C 1 ATOM 6173 O O . THR A 1 788 ? 24.491 78.898 -9.281 1.00 11.00 ? 788 THR A O 1 ATOM 6174 C CB . THR A 1 788 ? 22.822 81.209 -10.561 1.00 15.09 ? 788 THR A CB 1 ATOM 6175 O OG1 . THR A 1 788 ? 21.918 82.309 -10.337 1.00 16.52 ? 788 THR A OG1 1 ATOM 6176 C CG2 . THR A 1 788 ? 22.788 80.789 -12.038 1.00 14.77 ? 788 THR A CG2 1 ATOM 6177 N N . GLU A 1 789 ? 23.078 77.918 -10.725 1.00 11.75 ? 789 GLU A N 1 ATOM 6178 C CA . GLU A 1 789 ? 24.004 76.833 -11.060 1.00 12.16 ? 789 GLU A CA 1 ATOM 6179 C C . GLU A 1 789 ? 23.982 76.834 -12.583 1.00 12.28 ? 789 GLU A C 1 ATOM 6180 O O . GLU A 1 789 ? 22.914 76.729 -13.178 1.00 13.73 ? 789 GLU A O 1 ATOM 6181 C CB . GLU A 1 789 ? 23.544 75.460 -10.476 1.00 11.88 ? 789 GLU A CB 1 ATOM 6182 C CG . GLU A 1 789 ? 23.328 75.494 -8.957 1.00 10.61 ? 789 GLU A CG 1 ATOM 6183 C CD . GLU A 1 789 ? 23.504 74.135 -8.239 1.00 11.68 ? 789 GLU A CD 1 ATOM 6184 O OE1 . GLU A 1 789 ? 24.300 73.271 -8.718 1.00 11.68 ? 789 GLU A OE1 1 ATOM 6185 O OE2 . GLU A 1 789 ? 22.856 73.934 -7.183 1.00 11.46 ? 789 GLU A OE2 1 ATOM 6186 N N . ILE A 1 790 ? 25.146 77.015 -13.202 1.00 11.19 ? 790 ILE A N 1 ATOM 6187 C CA . ILE A 1 790 ? 25.271 77.037 -14.654 1.00 11.91 ? 790 ILE A CA 1 ATOM 6188 C C . ILE A 1 790 ? 25.626 75.645 -15.171 1.00 12.60 ? 790 ILE A C 1 ATOM 6189 O O . ILE A 1 790 ? 26.590 75.036 -14.709 1.00 12.95 ? 790 ILE A O 1 ATOM 6190 C CB . ILE A 1 790 ? 26.358 78.042 -15.090 1.00 13.86 ? 790 ILE A CB 1 ATOM 6191 C CG1 . ILE A 1 790 ? 25.956 79.443 -14.581 1.00 15.15 ? 790 ILE A CG1 1 ATOM 6192 C CG2 . ILE A 1 790 ? 26.524 78.034 -16.633 1.00 13.46 ? 790 ILE A CG2 1 ATOM 6193 C CD1 . ILE A 1 790 ? 27.078 80.475 -14.613 1.00 20.12 ? 790 ILE A CD1 1 ATOM 6194 N N . VAL A 1 791 ? 24.839 75.160 -16.126 1.00 10.88 ? 791 VAL A N 1 ATOM 6195 C CA . VAL A 1 791 ? 25.036 73.847 -16.694 1.00 11.07 ? 791 VAL A CA 1 ATOM 6196 C C . VAL A 1 791 ? 25.269 73.962 -18.183 1.00 10.50 ? 791 VAL A C 1 ATOM 6197 O O . VAL A 1 791 ? 24.741 74.865 -18.842 1.00 10.46 ? 791 VAL A O 1 ATOM 6198 C CB . VAL A 1 791 ? 23.790 72.947 -16.447 1.00 11.55 ? 791 VAL A CB 1 ATOM 6199 C CG1 . VAL A 1 791 ? 22.592 73.493 -17.190 1.00 11.55 ? 791 VAL A CG1 1 ATOM 6200 C CG2 . VAL A 1 791 ? 24.083 71.507 -16.877 1.00 11.24 ? 791 VAL A CG2 1 ATOM 6201 N N . MET A 1 792 ? 26.098 73.065 -18.697 1.00 11.01 ? 792 MET A N 1 ATOM 6202 C CA . MET A 1 792 ? 26.386 73.023 -20.118 1.00 10.66 ? 792 MET A CA 1 ATOM 6203 C C . MET A 1 792 ? 25.743 71.725 -20.585 1.00 10.82 ? 792 MET A C 1 ATOM 6204 O O . MET A 1 792 ? 26.034 70.666 -20.041 1.00 10.70 ? 792 MET A O 1 ATOM 6205 C CB . MET A 1 792 ? 27.899 72.988 -20.387 1.00 11.13 ? 792 MET A CB 1 ATOM 6206 C CG . MET A 1 792 ? 28.210 72.873 -21.890 1.00 8.34 ? 792 MET A CG 1 ATOM 6207 S SD . MET A 1 792 ? 30.009 72.899 -22.249 1.00 12.03 ? 792 MET A SD 1 ATOM 6208 C CE . MET A 1 792 ? 30.552 71.236 -21.528 1.00 9.67 ? 792 MET A CE 1 ATOM 6209 N N . ARG A 1 793 ? 24.878 71.816 -21.588 1.00 10.58 ? 793 ARG A N 1 ATOM 6210 C CA . ARG A 1 793 ? 24.173 70.657 -22.104 1.00 11.43 ? 793 ARG A CA 1 ATOM 6211 C C . ARG A 1 793 ? 24.427 70.409 -23.584 1.00 11.90 ? 793 ARG A C 1 ATOM 6212 O O . ARG A 1 793 ? 24.654 71.338 -24.357 1.00 11.71 ? 793 ARG A O 1 ATOM 6213 C CB . ARG A 1 793 ? 22.647 70.830 -21.873 1.00 11.49 ? 793 ARG A CB 1 ATOM 6214 C CG . ARG A 1 793 ? 21.750 69.657 -22.374 1.00 11.18 ? 793 ARG A CG 1 ATOM 6215 C CD . ARG A 1 793 ? 20.239 69.919 -22.041 1.00 12.29 ? 793 ARG A CD 1 ATOM 6216 N NE . ARG A 1 793 ? 19.988 69.964 -20.603 1.00 11.71 ? 793 ARG A NE 1 ATOM 6217 C CZ . ARG A 1 793 ? 18.923 70.521 -20.016 1.00 13.14 ? 793 ARG A CZ 1 ATOM 6218 N NH1 . ARG A 1 793 ? 17.961 71.109 -20.733 1.00 12.76 ? 793 ARG A NH1 1 ATOM 6219 N NH2 . ARG A 1 793 ? 18.828 70.513 -18.694 1.00 12.45 ? 793 ARG A NH2 1 ATOM 6220 N N . LEU A 1 794 ? 24.393 69.132 -23.954 1.00 11.76 ? 794 LEU A N 1 ATOM 6221 C CA . LEU A 1 794 ? 24.520 68.689 -25.338 1.00 11.92 ? 794 LEU A CA 1 ATOM 6222 C C . LEU A 1 794 ? 23.184 68.015 -25.697 1.00 13.50 ? 794 LEU A C 1 ATOM 6223 O O . LEU A 1 794 ? 22.698 67.152 -24.950 1.00 12.25 ? 794 LEU A O 1 ATOM 6224 C CB . LEU A 1 794 ? 25.680 67.685 -25.495 1.00 12.27 ? 794 LEU A CB 1 ATOM 6225 C CG . LEU A 1 794 ? 27.096 68.299 -25.500 1.00 12.11 ? 794 LEU A CG 1 ATOM 6226 C CD1 . LEU A 1 794 ? 28.166 67.312 -25.008 1.00 12.70 ? 794 LEU A CD1 1 ATOM 6227 C CD2 . LEU A 1 794 ? 27.409 68.736 -26.906 1.00 13.36 ? 794 LEU A CD2 1 ATOM 6228 N N . GLU A 1 795 ? 22.578 68.444 -26.812 1.00 12.55 ? 795 GLU A N 1 ATOM 6229 C CA . GLU A 1 795 ? 21.332 67.868 -27.306 1.00 13.32 ? 795 GLU A CA 1 ATOM 6230 C C . GLU A 1 795 ? 21.659 67.158 -28.627 1.00 13.41 ? 795 GLU A C 1 ATOM 6231 O O . GLU A 1 795 ? 22.277 67.740 -29.530 1.00 11.09 ? 795 GLU A O 1 ATOM 6232 C CB . GLU A 1 795 ? 20.283 68.971 -27.525 1.00 14.78 ? 795 GLU A CB 1 ATOM 6233 C CG . GLU A 1 795 ? 20.083 69.812 -26.276 1.00 16.73 ? 795 GLU A CG 1 ATOM 6234 C CD . GLU A 1 795 ? 19.150 71.006 -26.453 1.00 21.23 ? 795 GLU A CD 1 ATOM 6235 O OE1 . GLU A 1 795 ? 19.196 71.682 -27.509 1.00 22.42 ? 795 GLU A OE1 1 ATOM 6236 O OE2 . GLU A 1 795 ? 18.380 71.290 -25.521 1.00 21.18 ? 795 GLU A OE2 1 ATOM 6237 N N . THR A 1 796 ? 21.324 65.874 -28.700 1.00 12.14 ? 796 THR A N 1 ATOM 6238 C CA . THR A 1 796 ? 21.554 65.104 -29.901 1.00 13.31 ? 796 THR A CA 1 ATOM 6239 C C . THR A 1 796 ? 20.268 64.319 -30.143 1.00 14.62 ? 796 THR A C 1 ATOM 6240 O O . THR A 1 796 ? 19.307 64.388 -29.349 1.00 15.38 ? 796 THR A O 1 ATOM 6241 C CB . THR A 1 796 ? 22.696 64.043 -29.748 1.00 14.66 ? 796 THR A CB 1 ATOM 6242 O OG1 . THR A 1 796 ? 22.222 62.978 -28.904 1.00 13.80 ? 796 THR A OG1 1 ATOM 6243 C CG2 . THR A 1 796 ? 23.969 64.667 -29.158 1.00 14.19 ? 796 THR A CG2 1 ATOM 6244 N N . HIS A 1 797 ? 20.269 63.565 -31.226 1.00 15.38 ? 797 HIS A N 1 ATOM 6245 C CA . HIS A 1 797 ? 19.136 62.730 -31.574 1.00 17.32 ? 797 HIS A CA 1 ATOM 6246 C C . HIS A 1 797 ? 19.480 61.253 -31.323 1.00 17.49 ? 797 HIS A C 1 ATOM 6247 O O . HIS A 1 797 ? 18.736 60.352 -31.707 1.00 19.20 ? 797 HIS A O 1 ATOM 6248 C CB . HIS A 1 797 ? 18.721 63.034 -33.024 1.00 18.74 ? 797 HIS A CB 1 ATOM 6249 C CG . HIS A 1 797 ? 18.141 64.413 -33.182 1.00 18.92 ? 797 HIS A CG 1 ATOM 6250 N ND1 . HIS A 1 797 ? 17.960 65.017 -34.403 1.00 18.57 ? 797 HIS A ND1 1 ATOM 6251 C CD2 . HIS A 1 797 ? 17.740 65.322 -32.254 1.00 20.52 ? 797 HIS A CD2 1 ATOM 6252 C CE1 . HIS A 1 797 ? 17.479 66.236 -34.230 1.00 18.41 ? 797 HIS A CE1 1 ATOM 6253 N NE2 . HIS A 1 797 ? 17.331 66.449 -32.934 1.00 20.66 ? 797 HIS A NE2 1 ATOM 6254 N N . ILE A 1 798 ? 20.595 61.019 -30.623 1.00 16.67 ? 798 ILE A N 1 ATOM 6255 C CA . ILE A 1 798 ? 21.024 59.663 -30.262 1.00 15.56 ? 798 ILE A CA 1 ATOM 6256 C C . ILE A 1 798 ? 19.902 59.061 -29.426 1.00 15.47 ? 798 ILE A C 1 ATOM 6257 O O . ILE A 1 798 ? 19.379 59.691 -28.507 1.00 13.65 ? 798 ILE A O 1 ATOM 6258 C CB . ILE A 1 798 ? 22.343 59.678 -29.425 1.00 16.36 ? 798 ILE A CB 1 ATOM 6259 C CG1 . ILE A 1 798 ? 23.495 60.203 -30.295 1.00 15.22 ? 798 ILE A CG1 1 ATOM 6260 C CG2 . ILE A 1 798 ? 22.653 58.256 -28.886 1.00 13.93 ? 798 ILE A CG2 1 ATOM 6261 C CD1 . ILE A 1 798 ? 24.838 60.391 -29.542 1.00 14.28 ? 798 ILE A CD1 1 ATOM 6262 N N . ASP A 1 799 ? 19.531 57.831 -29.757 1.00 15.84 ? 799 ASP A N 1 ATOM 6263 C CA . ASP A 1 799 ? 18.443 57.156 -29.076 1.00 15.68 ? 799 ASP A CA 1 ATOM 6264 C C . ASP A 1 799 ? 18.953 56.359 -27.870 1.00 15.65 ? 799 ASP A C 1 ATOM 6265 O O . ASP A 1 799 ? 18.940 55.124 -27.881 1.00 13.85 ? 799 ASP A O 1 ATOM 6266 C CB . ASP A 1 799 ? 17.752 56.221 -30.070 1.00 17.88 ? 799 ASP A CB 1 ATOM 6267 C CG . ASP A 1 799 ? 16.458 55.644 -29.525 1.00 18.68 ? 799 ASP A CG 1 ATOM 6268 O OD1 . ASP A 1 799 ? 15.973 54.666 -30.113 1.00 21.20 ? 799 ASP A OD1 1 ATOM 6269 O OD2 . ASP A 1 799 ? 15.929 56.156 -28.515 1.00 21.15 ? 799 ASP A OD2 1 ATOM 6270 N N . SER A 1 800 ? 19.399 57.078 -26.839 1.00 15.67 ? 800 SER A N 1 ATOM 6271 C CA . SER A 1 800 ? 19.952 56.472 -25.616 1.00 14.33 ? 800 SER A CA 1 ATOM 6272 C C . SER A 1 800 ? 18.878 56.097 -24.586 1.00 14.56 ? 800 SER A C 1 ATOM 6273 O O . SER A 1 800 ? 19.135 55.326 -23.661 1.00 14.20 ? 800 SER A O 1 ATOM 6274 C CB . SER A 1 800 ? 20.944 57.449 -24.972 1.00 14.19 ? 800 SER A CB 1 ATOM 6275 O OG . SER A 1 800 ? 20.328 58.708 -24.766 1.00 12.50 ? 800 SER A OG 1 ATOM 6276 N N . GLY A 1 801 ? 17.676 56.647 -24.734 1.00 14.23 ? 801 GLY A N 1 ATOM 6277 C CA . GLY A 1 801 ? 16.602 56.306 -23.814 1.00 13.11 ? 801 GLY A CA 1 ATOM 6278 C C . GLY A 1 801 ? 16.912 56.800 -22.427 1.00 12.74 ? 801 GLY A C 1 ATOM 6279 O O . GLY A 1 801 ? 17.095 57.996 -22.249 1.00 13.66 ? 801 GLY A O 1 ATOM 6280 N N . ASP A 1 802 ? 16.979 55.898 -21.449 1.00 11.70 ? 802 ASP A N 1 ATOM 6281 C CA . ASP A 1 802 ? 17.268 56.277 -20.065 1.00 11.67 ? 802 ASP A CA 1 ATOM 6282 C C . ASP A 1 802 ? 18.666 55.804 -19.604 1.00 12.36 ? 802 ASP A C 1 ATOM 6283 O O . ASP A 1 802 ? 18.975 55.806 -18.406 1.00 12.81 ? 802 ASP A O 1 ATOM 6284 C CB . ASP A 1 802 ? 16.198 55.690 -19.130 1.00 12.28 ? 802 ASP A CB 1 ATOM 6285 C CG . ASP A 1 802 ? 16.069 54.172 -19.243 1.00 13.89 ? 802 ASP A CG 1 ATOM 6286 O OD1 . ASP A 1 802 ? 15.201 53.606 -18.529 1.00 16.13 ? 802 ASP A OD1 1 ATOM 6287 O OD2 . ASP A 1 802 ? 16.810 53.534 -20.031 1.00 14.03 ? 802 ASP A OD2 1 ATOM 6288 N N . ILE A 1 803 ? 19.505 55.416 -20.555 1.00 11.66 ? 803 ILE A N 1 ATOM 6289 C CA . ILE A 1 803 ? 20.844 54.934 -20.237 1.00 10.85 ? 803 ILE A CA 1 ATOM 6290 C C . ILE A 1 803 ? 21.952 55.934 -20.567 1.00 11.24 ? 803 ILE A C 1 ATOM 6291 O O . ILE A 1 803 ? 21.921 56.597 -21.608 1.00 10.06 ? 803 ILE A O 1 ATOM 6292 C CB . ILE A 1 803 ? 21.179 53.640 -21.059 1.00 11.03 ? 803 ILE A CB 1 ATOM 6293 C CG1 . ILE A 1 803 ? 20.195 52.505 -20.726 1.00 12.00 ? 803 ILE A CG1 1 ATOM 6294 C CG2 . ILE A 1 803 ? 22.627 53.228 -20.814 1.00 9.96 ? 803 ILE A CG2 1 ATOM 6295 C CD1 . ILE A 1 803 ? 20.099 52.145 -19.210 1.00 11.38 ? 803 ILE A CD1 1 ATOM 6296 N N . PHE A 1 804 ? 22.932 56.038 -19.677 1.00 9.68 ? 804 PHE A N 1 ATOM 6297 C CA . PHE A 1 804 ? 24.120 56.846 -19.949 1.00 10.14 ? 804 PHE A CA 1 ATOM 6298 C C . PHE A 1 804 ? 25.265 56.232 -19.119 1.00 11.16 ? 804 PHE A C 1 ATOM 6299 O O . PHE A 1 804 ? 25.021 55.372 -18.248 1.00 12.01 ? 804 PHE A O 1 ATOM 6300 C CB . PHE A 1 804 ? 23.906 58.360 -19.651 1.00 7.66 ? 804 PHE A CB 1 ATOM 6301 C CG . PHE A 1 804 ? 23.528 58.698 -18.213 1.00 8.67 ? 804 PHE A CG 1 ATOM 6302 C CD1 . PHE A 1 804 ? 24.461 59.333 -17.357 1.00 8.33 ? 804 PHE A CD1 1 ATOM 6303 C CD2 . PHE A 1 804 ? 22.250 58.429 -17.724 1.00 7.99 ? 804 PHE A CD2 1 ATOM 6304 C CE1 . PHE A 1 804 ? 24.116 59.683 -16.064 1.00 6.88 ? 804 PHE A CE1 1 ATOM 6305 C CE2 . PHE A 1 804 ? 21.889 58.774 -16.402 1.00 7.29 ? 804 PHE A CE2 1 ATOM 6306 C CZ . PHE A 1 804 ? 22.818 59.398 -15.577 1.00 8.02 ? 804 PHE A CZ 1 ATOM 6307 N N . TYR A 1 805 ? 26.493 56.653 -19.399 1.00 10.50 ? 805 TYR A N 1 ATOM 6308 C CA . TYR A 1 805 ? 27.656 56.133 -18.689 1.00 10.09 ? 805 TYR A CA 1 ATOM 6309 C C . TYR A 1 805 ? 28.478 57.273 -18.118 1.00 9.58 ? 805 TYR A C 1 ATOM 6310 O O . TYR A 1 805 ? 28.594 58.320 -18.742 1.00 8.41 ? 805 TYR A O 1 ATOM 6311 C CB . TYR A 1 805 ? 28.533 55.318 -19.630 1.00 8.86 ? 805 TYR A CB 1 ATOM 6312 C CG . TYR A 1 805 ? 27.846 54.082 -20.179 1.00 9.94 ? 805 TYR A CG 1 ATOM 6313 C CD1 . TYR A 1 805 ? 26.835 54.189 -21.164 1.00 8.98 ? 805 TYR A CD1 1 ATOM 6314 C CD2 . TYR A 1 805 ? 28.173 52.807 -19.701 1.00 8.81 ? 805 TYR A CD2 1 ATOM 6315 C CE1 . TYR A 1 805 ? 26.181 53.058 -21.656 1.00 9.48 ? 805 TYR A CE1 1 ATOM 6316 C CE2 . TYR A 1 805 ? 27.510 51.642 -20.200 1.00 9.65 ? 805 TYR A CE2 1 ATOM 6317 C CZ . TYR A 1 805 ? 26.522 51.791 -21.183 1.00 8.69 ? 805 TYR A CZ 1 ATOM 6318 O OH . TYR A 1 805 ? 25.906 50.683 -21.748 1.00 8.57 ? 805 TYR A OH 1 ATOM 6319 N N . THR A 1 806 ? 29.021 57.066 -16.918 1.00 8.59 ? 806 THR A N 1 ATOM 6320 C CA . THR A 1 806 ? 29.885 58.054 -16.274 1.00 8.41 ? 806 THR A CA 1 ATOM 6321 C C . THR A 1 806 ? 31.064 57.259 -15.668 1.00 8.19 ? 806 THR A C 1 ATOM 6322 O O . THR A 1 806 ? 30.924 56.077 -15.400 1.00 9.12 ? 806 THR A O 1 ATOM 6323 C CB . THR A 1 806 ? 29.156 58.817 -15.157 1.00 8.67 ? 806 THR A CB 1 ATOM 6324 O OG1 . THR A 1 806 ? 28.758 57.897 -14.123 1.00 10.34 ? 806 THR A OG1 1 ATOM 6325 C CG2 . THR A 1 806 ? 27.918 59.544 -15.715 1.00 6.19 ? 806 THR A CG2 1 ATOM 6326 N N . ASP A 1 807 ? 32.213 57.894 -15.446 1.00 7.56 ? 807 ASP A N 1 ATOM 6327 C CA . ASP A 1 807 ? 33.331 57.149 -14.899 1.00 7.72 ? 807 ASP A CA 1 ATOM 6328 C C . ASP A 1 807 ? 33.416 57.223 -13.375 1.00 8.67 ? 807 ASP A C 1 ATOM 6329 O O . ASP A 1 807 ? 32.779 58.084 -12.731 1.00 8.55 ? 807 ASP A O 1 ATOM 6330 C CB . ASP A 1 807 ? 34.674 57.617 -15.508 1.00 6.71 ? 807 ASP A CB 1 ATOM 6331 C CG . ASP A 1 807 ? 35.113 58.956 -15.006 1.00 9.32 ? 807 ASP A CG 1 ATOM 6332 O OD1 . ASP A 1 807 ? 36.273 59.056 -14.574 1.00 10.03 ? 807 ASP A OD1 1 ATOM 6333 O OD2 . ASP A 1 807 ? 34.315 59.912 -15.040 1.00 10.93 ? 807 ASP A OD2 1 ATOM 6334 N N . LEU A 1 808 ? 34.174 56.285 -12.807 1.00 7.42 ? 808 LEU A N 1 ATOM 6335 C CA . LEU A 1 808 ? 34.402 56.272 -11.372 1.00 8.15 ? 808 LEU A CA 1 ATOM 6336 C C . LEU A 1 808 ? 35.908 56.478 -11.180 1.00 7.88 ? 808 LEU A C 1 ATOM 6337 O O . LEU A 1 808 ? 36.718 55.620 -11.548 1.00 8.58 ? 808 LEU A O 1 ATOM 6338 C CB . LEU A 1 808 ? 33.932 54.949 -10.721 1.00 7.25 ? 808 LEU A CB 1 ATOM 6339 C CG . LEU A 1 808 ? 32.408 54.738 -10.572 1.00 8.26 ? 808 LEU A CG 1 ATOM 6340 C CD1 . LEU A 1 808 ? 32.140 53.245 -10.294 1.00 7.30 ? 808 LEU A CD1 1 ATOM 6341 C CD2 . LEU A 1 808 ? 31.856 55.563 -9.383 1.00 7.55 ? 808 LEU A CD2 1 ATOM 6342 N N . ASN A 1 809 ? 36.252 57.656 -10.654 1.00 7.26 ? 809 ASN A N 1 ATOM 6343 C CA . ASN A 1 809 ? 37.619 58.028 -10.343 1.00 6.87 ? 809 ASN A CA 1 ATOM 6344 C C . ASN A 1 809 ? 38.576 57.886 -11.501 1.00 6.44 ? 809 ASN A C 1 ATOM 6345 O O . ASN A 1 809 ? 39.721 57.546 -11.271 1.00 5.27 ? 809 ASN A O 1 ATOM 6346 C CB . ASN A 1 809 ? 38.134 57.172 -9.182 1.00 5.31 ? 809 ASN A CB 1 ATOM 6347 C CG . ASN A 1 809 ? 37.119 57.067 -8.051 1.00 6.96 ? 809 ASN A CG 1 ATOM 6348 O OD1 . ASN A 1 809 ? 36.274 56.146 -8.014 1.00 6.22 ? 809 ASN A OD1 1 ATOM 6349 N ND2 . ASN A 1 809 ? 37.156 58.038 -7.150 1.00 4.50 ? 809 ASN A ND2 1 ATOM 6350 N N . GLY A 1 810 ? 38.129 58.155 -12.726 1.00 7.22 ? 810 GLY A N 1 ATOM 6351 C CA . GLY A 1 810 ? 39.028 58.037 -13.868 1.00 7.97 ? 810 GLY A CA 1 ATOM 6352 C C . GLY A 1 810 ? 39.561 56.615 -14.084 1.00 10.20 ? 810 GLY A C 1 ATOM 6353 O O . GLY A 1 810 ? 40.551 56.390 -14.820 1.00 11.09 ? 810 GLY A O 1 ATOM 6354 N N . LEU A 1 811 ? 38.909 55.647 -13.458 1.00 8.44 ? 811 LEU A N 1 ATOM 6355 C CA . LEU A 1 811 ? 39.355 54.261 -13.546 1.00 10.46 ? 811 LEU A CA 1 ATOM 6356 C C . LEU A 1 811 ? 38.472 53.333 -14.385 1.00 10.56 ? 811 LEU A C 1 ATOM 6357 O O . LEU A 1 811 ? 38.972 52.439 -15.077 1.00 11.52 ? 811 LEU A O 1 ATOM 6358 C CB . LEU A 1 811 ? 39.481 53.670 -12.132 1.00 10.27 ? 811 LEU A CB 1 ATOM 6359 C CG . LEU A 1 811 ? 39.806 52.171 -12.035 1.00 13.23 ? 811 LEU A CG 1 ATOM 6360 C CD1 . LEU A 1 811 ? 41.245 51.938 -12.532 1.00 13.08 ? 811 LEU A CD1 1 ATOM 6361 C CD2 . LEU A 1 811 ? 39.638 51.683 -10.569 1.00 13.49 ? 811 LEU A CD2 1 ATOM 6362 N N . GLN A 1 812 ? 37.164 53.554 -14.347 1.00 8.88 ? 812 GLN A N 1 ATOM 6363 C CA . GLN A 1 812 ? 36.249 52.672 -15.057 1.00 8.88 ? 812 GLN A CA 1 ATOM 6364 C C . GLN A 1 812 ? 34.992 53.432 -15.384 1.00 8.90 ? 812 GLN A C 1 ATOM 6365 O O . GLN A 1 812 ? 34.716 54.444 -14.749 1.00 8.82 ? 812 GLN A O 1 ATOM 6366 C CB . GLN A 1 812 ? 35.849 51.526 -14.136 1.00 10.07 ? 812 GLN A CB 1 ATOM 6367 C CG . GLN A 1 812 ? 35.318 52.025 -12.761 1.00 10.70 ? 812 GLN A CG 1 ATOM 6368 C CD . GLN A 1 812 ? 35.011 50.872 -11.790 1.00 13.68 ? 812 GLN A CD 1 ATOM 6369 O OE1 . GLN A 1 812 ? 33.994 50.197 -11.913 1.00 12.88 ? 812 GLN A OE1 1 ATOM 6370 N NE2 . GLN A 1 812 ? 35.906 50.652 -10.826 1.00 14.30 ? 812 GLN A NE2 1 ATOM 6371 N N . PHE A 1 813 ? 34.232 52.925 -16.353 1.00 7.13 ? 813 PHE A N 1 ATOM 6372 C CA . PHE A 1 813 ? 32.968 53.539 -16.714 1.00 9.11 ? 813 PHE A CA 1 ATOM 6373 C C . PHE A 1 813 ? 31.850 52.615 -16.281 1.00 9.99 ? 813 PHE A C 1 ATOM 6374 O O . PHE A 1 813 ? 31.876 51.394 -16.535 1.00 10.53 ? 813 PHE A O 1 ATOM 6375 C CB . PHE A 1 813 ? 32.902 53.811 -18.222 1.00 9.31 ? 813 PHE A CB 1 ATOM 6376 C CG . PHE A 1 813 ? 33.627 55.060 -18.616 1.00 8.58 ? 813 PHE A CG 1 ATOM 6377 C CD1 . PHE A 1 813 ? 35.029 55.078 -18.674 1.00 7.63 ? 813 PHE A CD1 1 ATOM 6378 C CD2 . PHE A 1 813 ? 32.919 56.240 -18.838 1.00 10.43 ? 813 PHE A CD2 1 ATOM 6379 C CE1 . PHE A 1 813 ? 35.717 56.250 -18.946 1.00 7.03 ? 813 PHE A CE1 1 ATOM 6380 C CE2 . PHE A 1 813 ? 33.602 57.416 -19.108 1.00 10.40 ? 813 PHE A CE2 1 ATOM 6381 C CZ . PHE A 1 813 ? 35.026 57.400 -19.160 1.00 8.11 ? 813 PHE A CZ 1 ATOM 6382 N N . ILE A 1 814 ? 30.890 53.199 -15.589 1.00 9.18 ? 814 ILE A N 1 ATOM 6383 C CA . ILE A 1 814 ? 29.782 52.443 -15.068 1.00 7.72 ? 814 ILE A CA 1 ATOM 6384 C C . ILE A 1 814 ? 28.473 52.878 -15.729 1.00 8.78 ? 814 ILE A C 1 ATOM 6385 O O . ILE A 1 814 ? 28.237 54.058 -15.989 1.00 6.60 ? 814 ILE A O 1 ATOM 6386 C CB . ILE A 1 814 ? 29.739 52.612 -13.506 1.00 8.28 ? 814 ILE A CB 1 ATOM 6387 C CG1 . ILE A 1 814 ? 28.715 51.635 -12.889 1.00 7.62 ? 814 ILE A CG1 1 ATOM 6388 C CG2 . ILE A 1 814 ? 29.390 54.087 -13.128 1.00 5.33 ? 814 ILE A CG2 1 ATOM 6389 C CD1 . ILE A 1 814 ? 28.853 51.430 -11.328 1.00 6.58 ? 814 ILE A CD1 1 ATOM 6390 N N . LYS A 1 815 ? 27.632 51.900 -16.024 1.00 9.20 ? 815 LYS A N 1 ATOM 6391 C CA . LYS A 1 815 ? 26.345 52.161 -16.653 1.00 9.86 ? 815 LYS A CA 1 ATOM 6392 C C . LYS A 1 815 ? 25.385 52.774 -15.662 1.00 9.60 ? 815 LYS A C 1 ATOM 6393 O O . LYS A 1 815 ? 25.201 52.250 -14.550 1.00 11.10 ? 815 LYS A O 1 ATOM 6394 C CB . LYS A 1 815 ? 25.754 50.844 -17.183 1.00 9.76 ? 815 LYS A CB 1 ATOM 6395 C CG . LYS A 1 815 ? 24.403 50.958 -17.925 1.00 12.80 ? 815 LYS A CG 1 ATOM 6396 C CD . LYS A 1 815 ? 24.039 49.553 -18.469 1.00 16.89 ? 815 LYS A CD 1 ATOM 6397 C CE . LYS A 1 815 ? 22.811 49.575 -19.336 1.00 20.92 ? 815 LYS A CE 1 ATOM 6398 N NZ . LYS A 1 815 ? 22.579 48.198 -19.914 1.00 23.59 ? 815 LYS A NZ 1 ATOM 6399 N N . ARG A 1 816 ? 24.768 53.877 -16.067 1.00 9.00 ? 816 ARG A N 1 ATOM 6400 C CA . ARG A 1 816 ? 23.797 54.583 -15.234 1.00 8.63 ? 816 ARG A CA 1 ATOM 6401 C C . ARG A 1 816 ? 22.431 54.466 -15.894 1.00 8.95 ? 816 ARG A C 1 ATOM 6402 O O . ARG A 1 816 ? 22.351 54.351 -17.121 1.00 7.59 ? 816 ARG A O 1 ATOM 6403 C CB . ARG A 1 816 ? 24.132 56.081 -15.178 1.00 10.17 ? 816 ARG A CB 1 ATOM 6404 C CG . ARG A 1 816 ? 25.524 56.393 -14.694 1.00 9.00 ? 816 ARG A CG 1 ATOM 6405 C CD . ARG A 1 816 ? 25.670 55.852 -13.285 1.00 8.78 ? 816 ARG A CD 1 ATOM 6406 N NE . ARG A 1 816 ? 26.844 56.391 -12.618 1.00 8.72 ? 816 ARG A NE 1 ATOM 6407 C CZ . ARG A 1 816 ? 27.240 55.992 -11.412 1.00 10.34 ? 816 ARG A CZ 1 ATOM 6408 N NH1 . ARG A 1 816 ? 26.542 55.058 -10.793 1.00 6.81 ? 816 ARG A NH1 1 ATOM 6409 N NH2 . ARG A 1 816 ? 28.330 56.511 -10.839 1.00 9.28 ? 816 ARG A NH2 1 ATOM 6410 N N . ARG A 1 817 ? 21.366 54.486 -15.095 1.00 7.99 ? 817 ARG A N 1 ATOM 6411 C CA . ARG A 1 817 ? 20.014 54.457 -15.656 1.00 10.29 ? 817 ARG A CA 1 ATOM 6412 C C . ARG A 1 817 ? 19.214 55.589 -14.985 1.00 9.94 ? 817 ARG A C 1 ATOM 6413 O O . ARG A 1 817 ? 19.043 55.611 -13.764 1.00 11.60 ? 817 ARG A O 1 ATOM 6414 C CB . ARG A 1 817 ? 19.299 53.091 -15.450 1.00 11.00 ? 817 ARG A CB 1 ATOM 6415 C CG . ARG A 1 817 ? 17.813 53.116 -15.957 1.00 12.42 ? 817 ARG A CG 1 ATOM 6416 C CD . ARG A 1 817 ? 17.015 51.815 -15.679 1.00 12.83 ? 817 ARG A CD 1 ATOM 6417 N NE . ARG A 1 817 ? 17.498 50.757 -16.552 1.00 14.53 ? 817 ARG A NE 1 ATOM 6418 C CZ . ARG A 1 817 ? 18.269 49.756 -16.158 1.00 15.30 ? 817 ARG A CZ 1 ATOM 6419 N NH1 . ARG A 1 817 ? 18.622 49.662 -14.883 1.00 14.99 ? 817 ARG A NH1 1 ATOM 6420 N NH2 . ARG A 1 817 ? 18.731 48.890 -17.053 1.00 15.62 ? 817 ARG A NH2 1 ATOM 6421 N N . ARG A 1 818 ? 18.786 56.556 -15.790 1.00 10.04 ? 818 ARG A N 1 ATOM 6422 C CA . ARG A 1 818 ? 18.010 57.700 -15.298 1.00 11.27 ? 818 ARG A CA 1 ATOM 6423 C C . ARG A 1 818 ? 16.715 57.117 -14.731 1.00 11.50 ? 818 ARG A C 1 ATOM 6424 O O . ARG A 1 818 ? 16.057 56.334 -15.411 1.00 12.70 ? 818 ARG A O 1 ATOM 6425 C CB . ARG A 1 818 ? 17.667 58.644 -16.468 1.00 12.02 ? 818 ARG A CB 1 ATOM 6426 C CG . ARG A 1 818 ? 16.948 59.937 -16.042 1.00 14.07 ? 818 ARG A CG 1 ATOM 6427 C CD . ARG A 1 818 ? 16.307 60.662 -17.247 1.00 14.49 ? 818 ARG A CD 1 ATOM 6428 N NE . ARG A 1 818 ? 15.018 60.029 -17.571 1.00 16.69 ? 818 ARG A NE 1 ATOM 6429 C CZ . ARG A 1 818 ? 14.720 59.421 -18.720 1.00 17.02 ? 818 ARG A CZ 1 ATOM 6430 N NH1 . ARG A 1 818 ? 15.611 59.348 -19.719 1.00 14.46 ? 818 ARG A NH1 1 ATOM 6431 N NH2 . ARG A 1 818 ? 13.518 58.842 -18.848 1.00 15.89 ? 818 ARG A NH2 1 ATOM 6432 N N . LEU A 1 819 ? 16.353 57.478 -13.511 1.00 10.66 ? 819 LEU A N 1 ATOM 6433 C CA . LEU A 1 819 ? 15.147 56.920 -12.903 1.00 12.15 ? 819 LEU A CA 1 ATOM 6434 C C . LEU A 1 819 ? 14.170 58.043 -12.621 1.00 13.05 ? 819 LEU A C 1 ATOM 6435 O O . LEU A 1 819 ? 14.435 58.904 -11.768 1.00 12.59 ? 819 LEU A O 1 ATOM 6436 C CB . LEU A 1 819 ? 15.492 56.200 -11.595 1.00 11.27 ? 819 LEU A CB 1 ATOM 6437 C CG . LEU A 1 819 ? 16.364 54.943 -11.760 1.00 10.78 ? 819 LEU A CG 1 ATOM 6438 C CD1 . LEU A 1 819 ? 16.845 54.473 -10.405 1.00 10.44 ? 819 LEU A CD1 1 ATOM 6439 C CD2 . LEU A 1 819 ? 15.555 53.818 -12.486 1.00 11.08 ? 819 LEU A CD2 1 ATOM 6440 N N . ASP A 1 820 ? 13.048 58.044 -13.340 1.00 12.87 ? 820 ASP A N 1 ATOM 6441 C CA . ASP A 1 820 ? 12.084 59.108 -13.131 1.00 14.38 ? 820 ASP A CA 1 ATOM 6442 C C . ASP A 1 820 ? 11.367 58.963 -11.798 1.00 14.00 ? 820 ASP A C 1 ATOM 6443 O O . ASP A 1 820 ? 10.737 59.915 -11.316 1.00 13.29 ? 820 ASP A O 1 ATOM 6444 C CB . ASP A 1 820 ? 11.119 59.203 -14.325 1.00 15.78 ? 820 ASP A CB 1 ATOM 6445 C CG . ASP A 1 820 ? 11.851 59.566 -15.641 1.00 19.42 ? 820 ASP A CG 1 ATOM 6446 O OD1 . ASP A 1 820 ? 12.912 60.260 -15.609 1.00 21.09 ? 820 ASP A OD1 1 ATOM 6447 O OD2 . ASP A 1 820 ? 11.368 59.160 -16.714 1.00 18.60 ? 820 ASP A OD2 1 ATOM 6448 N N . LYS A 1 821 ? 11.487 57.796 -11.163 1.00 13.18 ? 821 LYS A N 1 ATOM 6449 C CA . LYS A 1 821 ? 10.848 57.660 -9.838 1.00 14.56 ? 821 LYS A CA 1 ATOM 6450 C C . LYS A 1 821 ? 11.690 58.428 -8.807 1.00 14.33 ? 821 LYS A C 1 ATOM 6451 O O . LYS A 1 821 ? 11.286 58.579 -7.664 1.00 15.75 ? 821 LYS A O 1 ATOM 6452 C CB . LYS A 1 821 ? 10.708 56.189 -9.395 1.00 14.42 ? 821 LYS A CB 1 ATOM 6453 C CG . LYS A 1 821 ? 12.031 55.471 -9.212 1.00 14.98 ? 821 LYS A CG 1 ATOM 6454 C CD . LYS A 1 821 ? 11.851 53.965 -9.065 1.00 15.14 ? 821 LYS A CD 1 ATOM 6455 C CE . LYS A 1 821 ? 13.194 53.279 -9.022 1.00 15.92 ? 821 LYS A CE 1 ATOM 6456 N NZ . LYS A 1 821 ? 13.071 51.807 -9.085 1.00 13.32 ? 821 LYS A NZ 1 ATOM 6457 N N . LEU A 1 822 ? 12.855 58.929 -9.212 1.00 13.80 ? 822 LEU A N 1 ATOM 6458 C CA . LEU A 1 822 ? 13.688 59.704 -8.285 1.00 12.37 ? 822 LEU A CA 1 ATOM 6459 C C . LEU A 1 822 ? 13.743 61.156 -8.746 1.00 12.93 ? 822 LEU A C 1 ATOM 6460 O O . LEU A 1 822 ? 13.623 61.432 -9.938 1.00 12.10 ? 822 LEU A O 1 ATOM 6461 C CB . LEU A 1 822 ? 15.122 59.162 -8.258 1.00 12.36 ? 822 LEU A CB 1 ATOM 6462 C CG . LEU A 1 822 ? 15.293 57.700 -7.793 1.00 12.90 ? 822 LEU A CG 1 ATOM 6463 C CD1 . LEU A 1 822 ? 16.759 57.379 -7.688 1.00 10.70 ? 822 LEU A CD1 1 ATOM 6464 C CD2 . LEU A 1 822 ? 14.629 57.522 -6.411 1.00 11.72 ? 822 LEU A CD2 1 ATOM 6465 N N . PRO A 1 823 ? 13.937 62.093 -7.811 1.00 12.53 ? 823 PRO A N 1 ATOM 6466 C CA . PRO A 1 823 ? 14.017 63.510 -8.167 1.00 12.49 ? 823 PRO A CA 1 ATOM 6467 C C . PRO A 1 823 ? 15.251 63.813 -9.030 1.00 14.48 ? 823 PRO A C 1 ATOM 6468 O O . PRO A 1 823 ? 16.252 63.069 -9.032 1.00 13.27 ? 823 PRO A O 1 ATOM 6469 C CB . PRO A 1 823 ? 14.042 64.211 -6.817 1.00 12.75 ? 823 PRO A CB 1 ATOM 6470 C CG . PRO A 1 823 ? 14.695 63.230 -5.909 1.00 13.51 ? 823 PRO A CG 1 ATOM 6471 C CD . PRO A 1 823 ? 14.029 61.904 -6.353 1.00 12.62 ? 823 PRO A CD 1 ATOM 6472 N N . LEU A 1 824 ? 15.172 64.924 -9.761 1.00 13.09 ? 824 LEU A N 1 ATOM 6473 C CA . LEU A 1 824 ? 16.238 65.333 -10.668 1.00 13.02 ? 824 LEU A CA 1 ATOM 6474 C C . LEU A 1 824 ? 17.671 65.206 -10.093 1.00 13.09 ? 824 LEU A C 1 ATOM 6475 O O . LEU A 1 824 ? 18.578 64.627 -10.723 1.00 10.81 ? 824 LEU A O 1 ATOM 6476 C CB . LEU A 1 824 ? 15.983 66.792 -11.074 1.00 12.71 ? 824 LEU A CB 1 ATOM 6477 C CG . LEU A 1 824 ? 16.756 67.345 -12.281 1.00 14.04 ? 824 LEU A CG 1 ATOM 6478 C CD1 . LEU A 1 824 ? 15.912 68.533 -12.861 1.00 12.68 ? 824 LEU A CD1 1 ATOM 6479 C CD2 . LEU A 1 824 ? 18.210 67.788 -11.912 1.00 10.90 ? 824 LEU A CD2 1 ATOM 6480 N N . GLN A 1 825 ? 17.851 65.737 -8.885 1.00 11.96 ? 825 GLN A N 1 ATOM 6481 C CA . GLN A 1 825 ? 19.162 65.770 -8.268 1.00 11.28 ? 825 GLN A CA 1 ATOM 6482 C C . GLN A 1 825 ? 19.739 64.403 -7.988 1.00 11.92 ? 825 GLN A C 1 ATOM 6483 O O . GLN A 1 825 ? 20.969 64.258 -7.850 1.00 11.66 ? 825 GLN A O 1 ATOM 6484 C CB . GLN A 1 825 ? 19.129 66.623 -6.992 1.00 11.00 ? 825 GLN A CB 1 ATOM 6485 C CG . GLN A 1 825 ? 18.214 66.115 -5.853 1.00 11.41 ? 825 GLN A CG 1 ATOM 6486 C CD . GLN A 1 825 ? 16.776 66.611 -5.932 1.00 12.61 ? 825 GLN A CD 1 ATOM 6487 O OE1 . GLN A 1 825 ? 16.318 67.071 -6.980 1.00 13.20 ? 825 GLN A OE1 1 ATOM 6488 N NE2 . GLN A 1 825 ? 16.048 66.498 -4.815 1.00 12.36 ? 825 GLN A NE2 1 ATOM 6489 N N . ALA A 1 826 ? 18.861 63.406 -7.905 1.00 10.20 ? 826 ALA A N 1 ATOM 6490 C CA . ALA A 1 826 ? 19.295 62.033 -7.652 1.00 10.15 ? 826 ALA A CA 1 ATOM 6491 C C . ALA A 1 826 ? 19.848 61.431 -8.945 1.00 10.83 ? 826 ALA A C 1 ATOM 6492 O O . ALA A 1 826 ? 20.613 60.474 -8.914 1.00 10.23 ? 826 ALA A O 1 ATOM 6493 C CB . ALA A 1 826 ? 18.121 61.206 -7.146 1.00 10.22 ? 826 ALA A CB 1 ATOM 6494 N N . ASN A 1 827 ? 19.449 61.971 -10.099 1.00 10.85 ? 827 ASN A N 1 ATOM 6495 C CA . ASN A 1 827 ? 19.978 61.426 -11.345 1.00 11.05 ? 827 ASN A CA 1 ATOM 6496 C C . ASN A 1 827 ? 21.291 62.091 -11.728 1.00 10.42 ? 827 ASN A C 1 ATOM 6497 O O . ASN A 1 827 ? 21.820 61.865 -12.821 1.00 11.22 ? 827 ASN A O 1 ATOM 6498 C CB . ASN A 1 827 ? 18.920 61.512 -12.450 1.00 11.33 ? 827 ASN A CB 1 ATOM 6499 C CG . ASN A 1 827 ? 17.769 60.557 -12.181 1.00 12.91 ? 827 ASN A CG 1 ATOM 6500 O OD1 . ASN A 1 827 ? 17.943 59.361 -12.290 1.00 11.54 ? 827 ASN A OD1 1 ATOM 6501 N ND2 . ASN A 1 827 ? 16.618 61.082 -11.772 1.00 12.18 ? 827 ASN A ND2 1 ATOM 6502 N N . TYR A 1 828 ? 21.800 62.943 -10.832 1.00 10.64 ? 828 TYR A N 1 ATOM 6503 C CA . TYR A 1 828 ? 23.112 63.569 -11.051 1.00 10.35 ? 828 TYR A CA 1 ATOM 6504 C C . TYR A 1 828 ? 24.161 62.622 -10.447 1.00 10.79 ? 828 TYR A C 1 ATOM 6505 O O . TYR A 1 828 ? 23.932 62.034 -9.371 1.00 10.37 ? 828 TYR A O 1 ATOM 6506 C CB . TYR A 1 828 ? 23.224 64.947 -10.381 1.00 8.74 ? 828 TYR A CB 1 ATOM 6507 C CG . TYR A 1 828 ? 23.242 66.095 -11.382 1.00 8.55 ? 828 TYR A CG 1 ATOM 6508 C CD1 . TYR A 1 828 ? 22.147 66.348 -12.226 1.00 7.07 ? 828 TYR A CD1 1 ATOM 6509 C CD2 . TYR A 1 828 ? 24.373 66.905 -11.519 1.00 8.95 ? 828 TYR A CD2 1 ATOM 6510 C CE1 . TYR A 1 828 ? 22.195 67.364 -13.181 1.00 7.63 ? 828 TYR A CE1 1 ATOM 6511 C CE2 . TYR A 1 828 ? 24.417 67.933 -12.470 1.00 9.25 ? 828 TYR A CE2 1 ATOM 6512 C CZ . TYR A 1 828 ? 23.340 68.153 -13.296 1.00 7.95 ? 828 TYR A CZ 1 ATOM 6513 O OH . TYR A 1 828 ? 23.438 69.122 -14.280 1.00 9.46 ? 828 TYR A OH 1 ATOM 6514 N N . TYR A 1 829 ? 25.271 62.455 -11.172 1.00 9.63 ? 829 TYR A N 1 ATOM 6515 C CA . TYR A 1 829 ? 26.384 61.593 -10.765 1.00 10.16 ? 829 TYR A CA 1 ATOM 6516 C C . TYR A 1 829 ? 27.720 62.326 -10.917 1.00 10.50 ? 829 TYR A C 1 ATOM 6517 O O . TYR A 1 829 ? 27.809 63.347 -11.606 1.00 8.65 ? 829 TYR A O 1 ATOM 6518 C CB . TYR A 1 829 ? 26.444 60.326 -11.632 1.00 9.04 ? 829 TYR A CB 1 ATOM 6519 C CG . TYR A 1 829 ? 25.289 59.403 -11.396 1.00 9.09 ? 829 TYR A CG 1 ATOM 6520 C CD1 . TYR A 1 829 ? 24.114 59.489 -12.172 1.00 10.13 ? 829 TYR A CD1 1 ATOM 6521 C CD2 . TYR A 1 829 ? 25.334 58.486 -10.358 1.00 8.53 ? 829 TYR A CD2 1 ATOM 6522 C CE1 . TYR A 1 829 ? 22.992 58.656 -11.891 1.00 9.31 ? 829 TYR A CE1 1 ATOM 6523 C CE2 . TYR A 1 829 ? 24.245 57.662 -10.058 1.00 9.37 ? 829 TYR A CE2 1 ATOM 6524 C CZ . TYR A 1 829 ? 23.068 57.748 -10.824 1.00 10.52 ? 829 TYR A CZ 1 ATOM 6525 O OH . TYR A 1 829 ? 22.000 56.955 -10.473 1.00 9.05 ? 829 TYR A OH 1 ATOM 6526 N N . PRO A 1 830 ? 28.770 61.819 -10.250 1.00 10.49 ? 830 PRO A N 1 ATOM 6527 C CA . PRO A 1 830 ? 30.058 62.498 -10.395 1.00 9.59 ? 830 PRO A CA 1 ATOM 6528 C C . PRO A 1 830 ? 30.517 62.237 -11.829 1.00 9.57 ? 830 PRO A C 1 ATOM 6529 O O . PRO A 1 830 ? 30.270 61.138 -12.376 1.00 6.75 ? 830 PRO A O 1 ATOM 6530 C CB . PRO A 1 830 ? 30.992 61.750 -9.437 1.00 11.97 ? 830 PRO A CB 1 ATOM 6531 C CG . PRO A 1 830 ? 30.072 60.991 -8.478 1.00 12.86 ? 830 PRO A CG 1 ATOM 6532 C CD . PRO A 1 830 ? 28.800 60.711 -9.269 1.00 10.29 ? 830 PRO A CD 1 ATOM 6533 N N . ILE A 1 831 ? 31.160 63.223 -12.441 1.00 6.97 ? 831 ILE A N 1 ATOM 6534 C CA . ILE A 1 831 ? 31.748 63.030 -13.785 1.00 7.68 ? 831 ILE A CA 1 ATOM 6535 C C . ILE A 1 831 ? 33.230 63.352 -13.513 1.00 8.08 ? 831 ILE A C 1 ATOM 6536 O O . ILE A 1 831 ? 33.721 64.417 -13.870 1.00 7.01 ? 831 ILE A O 1 ATOM 6537 C CB . ILE A 1 831 ? 31.219 64.029 -14.849 1.00 6.42 ? 831 ILE A CB 1 ATOM 6538 C CG1 . ILE A 1 831 ? 29.673 64.088 -14.845 1.00 7.11 ? 831 ILE A CG1 1 ATOM 6539 C CG2 . ILE A 1 831 ? 31.784 63.640 -16.222 1.00 6.01 ? 831 ILE A CG2 1 ATOM 6540 C CD1 . ILE A 1 831 ? 28.943 62.730 -15.048 1.00 6.86 ? 831 ILE A CD1 1 ATOM 6541 N N . PRO A 1 832 ? 33.965 62.406 -12.899 1.00 9.17 ? 832 PRO A N 1 ATOM 6542 C CA . PRO A 1 832 ? 35.373 62.713 -12.604 1.00 7.88 ? 832 PRO A CA 1 ATOM 6543 C C . PRO A 1 832 ? 36.280 62.882 -13.788 1.00 8.56 ? 832 PRO A C 1 ATOM 6544 O O . PRO A 1 832 ? 37.272 63.602 -13.692 1.00 6.26 ? 832 PRO A O 1 ATOM 6545 C CB . PRO A 1 832 ? 35.808 61.596 -11.634 1.00 8.92 ? 832 PRO A CB 1 ATOM 6546 C CG . PRO A 1 832 ? 34.832 60.472 -11.891 1.00 10.93 ? 832 PRO A CG 1 ATOM 6547 C CD . PRO A 1 832 ? 33.516 61.192 -12.194 1.00 8.26 ? 832 PRO A CD 1 ATOM 6548 N N . SER A 1 833 ? 35.955 62.245 -14.910 1.00 8.21 ? 833 SER A N 1 ATOM 6549 C CA . SER A 1 833 ? 36.791 62.427 -16.091 1.00 8.85 ? 833 SER A CA 1 ATOM 6550 C C . SER A 1 833 ? 36.049 62.199 -17.422 1.00 8.51 ? 833 SER A C 1 ATOM 6551 O O . SER A 1 833 ? 36.584 62.506 -18.476 1.00 7.04 ? 833 SER A O 1 ATOM 6552 C CB . SER A 1 833 ? 38.017 61.505 -16.031 1.00 10.30 ? 833 SER A CB 1 ATOM 6553 O OG . SER A 1 833 ? 37.710 60.167 -16.358 1.00 11.23 ? 833 SER A OG 1 ATOM 6554 N N . GLY A 1 834 ? 34.832 61.652 -17.368 1.00 7.74 ? 834 GLY A N 1 ATOM 6555 C CA . GLY A 1 834 ? 34.107 61.432 -18.619 1.00 7.09 ? 834 GLY A CA 1 ATOM 6556 C C . GLY A 1 834 ? 32.719 60.833 -18.516 1.00 7.70 ? 834 GLY A C 1 ATOM 6557 O O . GLY A 1 834 ? 32.323 60.189 -17.524 1.00 6.52 ? 834 GLY A O 1 ATOM 6558 N N . MET A 1 835 ? 31.954 61.058 -19.572 1.00 9.11 ? 835 MET A N 1 ATOM 6559 C CA . MET A 1 835 ? 30.594 60.545 -19.637 1.00 9.35 ? 835 MET A CA 1 ATOM 6560 C C . MET A 1 835 ? 30.214 60.322 -21.121 1.00 10.27 ? 835 MET A C 1 ATOM 6561 O O . MET A 1 835 ? 30.784 60.947 -22.029 1.00 9.26 ? 835 MET A O 1 ATOM 6562 C CB . MET A 1 835 ? 29.632 61.556 -18.997 1.00 8.13 ? 835 MET A CB 1 ATOM 6563 C CG . MET A 1 835 ? 29.423 62.863 -19.814 1.00 8.24 ? 835 MET A CG 1 ATOM 6564 S SD . MET A 1 835 ? 28.649 64.168 -18.859 1.00 11.21 ? 835 MET A SD 1 ATOM 6565 C CE . MET A 1 835 ? 27.070 63.461 -18.542 1.00 6.22 ? 835 MET A CE 1 ATOM 6566 N N . PHE A 1 836 ? 29.278 59.410 -21.370 1.00 9.64 ? 836 PHE A N 1 ATOM 6567 C CA . PHE A 1 836 ? 28.841 59.216 -22.749 1.00 9.35 ? 836 PHE A CA 1 ATOM 6568 C C . PHE A 1 836 ? 27.445 58.611 -22.842 1.00 10.11 ? 836 PHE A C 1 ATOM 6569 O O . PHE A 1 836 ? 26.911 58.075 -21.860 1.00 7.75 ? 836 PHE A O 1 ATOM 6570 C CB . PHE A 1 836 ? 29.881 58.400 -23.556 1.00 8.42 ? 836 PHE A CB 1 ATOM 6571 C CG . PHE A 1 836 ? 30.010 56.918 -23.170 1.00 10.87 ? 836 PHE A CG 1 ATOM 6572 C CD1 . PHE A 1 836 ? 29.117 55.955 -23.677 1.00 10.91 ? 836 PHE A CD1 1 ATOM 6573 C CD2 . PHE A 1 836 ? 31.071 56.479 -22.386 1.00 9.47 ? 836 PHE A CD2 1 ATOM 6574 C CE1 . PHE A 1 836 ? 29.291 54.582 -23.410 1.00 10.14 ? 836 PHE A CE1 1 ATOM 6575 C CE2 . PHE A 1 836 ? 31.256 55.095 -22.107 1.00 10.47 ? 836 PHE A CE2 1 ATOM 6576 C CZ . PHE A 1 836 ? 30.370 54.156 -22.618 1.00 11.92 ? 836 PHE A CZ 1 ATOM 6577 N N . ILE A 1 837 ? 26.844 58.766 -24.022 1.00 9.30 ? 837 ILE A N 1 ATOM 6578 C CA . ILE A 1 837 ? 25.550 58.183 -24.321 1.00 9.67 ? 837 ILE A CA 1 ATOM 6579 C C . ILE A 1 837 ? 25.721 57.520 -25.673 1.00 10.15 ? 837 ILE A C 1 ATOM 6580 O O . ILE A 1 837 ? 26.606 57.907 -26.475 1.00 8.51 ? 837 ILE A O 1 ATOM 6581 C CB . ILE A 1 837 ? 24.426 59.222 -24.447 1.00 9.37 ? 837 ILE A CB 1 ATOM 6582 C CG1 . ILE A 1 837 ? 24.868 60.391 -25.313 1.00 10.13 ? 837 ILE A CG1 1 ATOM 6583 C CG2 . ILE A 1 837 ? 23.955 59.639 -23.074 1.00 9.83 ? 837 ILE A CG2 1 ATOM 6584 C CD1 . ILE A 1 837 ? 23.645 61.296 -25.742 1.00 8.26 ? 837 ILE A CD1 1 ATOM 6585 N N . GLU A 1 838 ? 24.892 56.527 -25.938 1.00 10.49 ? 838 GLU A N 1 ATOM 6586 C CA . GLU A 1 838 ? 24.972 55.851 -27.225 1.00 12.01 ? 838 GLU A CA 1 ATOM 6587 C C . GLU A 1 838 ? 23.705 55.072 -27.585 1.00 12.23 ? 838 GLU A C 1 ATOM 6588 O O . GLU A 1 838 ? 22.823 54.822 -26.740 1.00 11.05 ? 838 GLU A O 1 ATOM 6589 C CB . GLU A 1 838 ? 26.142 54.856 -27.209 1.00 11.71 ? 838 GLU A CB 1 ATOM 6590 C CG . GLU A 1 838 ? 25.881 53.661 -26.239 1.00 13.67 ? 838 GLU A CG 1 ATOM 6591 C CD . GLU A 1 838 ? 27.024 52.624 -26.197 1.00 15.77 ? 838 GLU A CD 1 ATOM 6592 O OE1 . GLU A 1 838 ? 26.865 51.610 -25.488 1.00 17.87 ? 838 GLU A OE1 1 ATOM 6593 O OE2 . GLU A 1 838 ? 28.060 52.796 -26.866 1.00 16.28 ? 838 GLU A OE2 1 ATOM 6594 N N . ASP A 1 839 ? 23.596 54.718 -28.862 1.00 13.18 ? 839 ASP A N 1 ATOM 6595 C CA . ASP A 1 839 ? 22.519 53.840 -29.280 1.00 13.77 ? 839 ASP A CA 1 ATOM 6596 C C . ASP A 1 839 ? 23.224 52.750 -30.063 1.00 14.86 ? 839 ASP A C 1 ATOM 6597 O O . ASP A 1 839 ? 24.438 52.569 -29.921 1.00 13.03 ? 839 ASP A O 1 ATOM 6598 C CB . ASP A 1 839 ? 21.417 54.526 -30.095 1.00 13.76 ? 839 ASP A CB 1 ATOM 6599 C CG . ASP A 1 839 ? 21.933 55.286 -31.289 1.00 13.70 ? 839 ASP A CG 1 ATOM 6600 O OD1 . ASP A 1 839 ? 23.001 54.945 -31.845 1.00 12.30 ? 839 ASP A OD1 1 ATOM 6601 O OD2 . ASP A 1 839 ? 21.223 56.235 -31.667 1.00 14.99 ? 839 ASP A OD2 1 ATOM 6602 N N . ALA A 1 840 ? 22.491 52.034 -30.909 1.00 15.27 ? 840 ALA A N 1 ATOM 6603 C CA . ALA A 1 840 ? 23.105 50.951 -31.644 1.00 15.26 ? 840 ALA A CA 1 ATOM 6604 C C . ALA A 1 840 ? 24.207 51.409 -32.593 1.00 15.33 ? 840 ALA A C 1 ATOM 6605 O O . ALA A 1 840 ? 25.174 50.681 -32.822 1.00 14.37 ? 840 ALA A O 1 ATOM 6606 C CB . ALA A 1 840 ? 22.030 50.184 -32.426 1.00 14.56 ? 840 ALA A CB 1 ATOM 6607 N N . ASN A 1 841 ? 24.081 52.627 -33.114 1.00 14.45 ? 841 ASN A N 1 ATOM 6608 C CA . ASN A 1 841 ? 25.032 53.119 -34.102 1.00 14.65 ? 841 ASN A CA 1 ATOM 6609 C C . ASN A 1 841 ? 25.976 54.260 -33.764 1.00 14.11 ? 841 ASN A C 1 ATOM 6610 O O . ASN A 1 841 ? 27.059 54.375 -34.346 1.00 13.31 ? 841 ASN A O 1 ATOM 6611 C CB . ASN A 1 841 ? 24.244 53.546 -35.353 1.00 15.68 ? 841 ASN A CB 1 ATOM 6612 C CG . ASN A 1 841 ? 23.493 52.386 -35.969 1.00 17.64 ? 841 ASN A CG 1 ATOM 6613 O OD1 . ASN A 1 841 ? 24.071 51.331 -36.190 1.00 18.30 ? 841 ASN A OD1 1 ATOM 6614 N ND2 . ASN A 1 841 ? 22.212 52.569 -36.230 1.00 16.23 ? 841 ASN A ND2 1 ATOM 6615 N N . THR A 1 842 ? 25.541 55.114 -32.866 1.00 13.45 ? 842 THR A N 1 ATOM 6616 C CA . THR A 1 842 ? 26.307 56.305 -32.555 1.00 13.77 ? 842 THR A CA 1 ATOM 6617 C C . THR A 1 842 ? 26.540 56.525 -31.075 1.00 12.82 ? 842 THR A C 1 ATOM 6618 O O . THR A 1 842 ? 25.704 56.169 -30.232 1.00 12.67 ? 842 THR A O 1 ATOM 6619 C CB . THR A 1 842 ? 25.574 57.546 -33.133 1.00 14.01 ? 842 THR A CB 1 ATOM 6620 O OG1 . THR A 1 842 ? 25.153 57.264 -34.471 1.00 13.50 ? 842 THR A OG1 1 ATOM 6621 C CG2 . THR A 1 842 ? 26.475 58.770 -33.136 1.00 14.97 ? 842 THR A CG2 1 ATOM 6622 N N . ARG A 1 843 ? 27.705 57.090 -30.776 1.00 11.70 ? 843 ARG A N 1 ATOM 6623 C CA . ARG A 1 843 ? 28.061 57.430 -29.407 1.00 11.59 ? 843 ARG A CA 1 ATOM 6624 C C . ARG A 1 843 ? 28.621 58.853 -29.361 1.00 11.32 ? 843 ARG A C 1 ATOM 6625 O O . ARG A 1 843 ? 29.315 59.294 -30.281 1.00 10.17 ? 843 ARG A O 1 ATOM 6626 C CB . ARG A 1 843 ? 29.154 56.493 -28.865 1.00 11.17 ? 843 ARG A CB 1 ATOM 6627 C CG . ARG A 1 843 ? 29.615 56.861 -27.430 1.00 10.00 ? 843 ARG A CG 1 ATOM 6628 C CD . ARG A 1 843 ? 30.771 55.970 -26.927 1.00 6.69 ? 843 ARG A CD 1 ATOM 6629 N NE . ARG A 1 843 ? 30.372 54.581 -26.618 1.00 8.86 ? 843 ARG A NE 1 ATOM 6630 C CZ . ARG A 1 843 ? 31.210 53.686 -26.079 1.00 10.05 ? 843 ARG A CZ 1 ATOM 6631 N NH1 . ARG A 1 843 ? 32.465 54.045 -25.807 1.00 8.91 ? 843 ARG A NH1 1 ATOM 6632 N NH2 . ARG A 1 843 ? 30.814 52.448 -25.783 1.00 9.17 ? 843 ARG A NH2 1 ATOM 6633 N N . LEU A 1 844 ? 28.314 59.561 -28.280 1.00 11.83 ? 844 LEU A N 1 ATOM 6634 C CA . LEU A 1 844 ? 28.880 60.891 -28.073 1.00 10.68 ? 844 LEU A CA 1 ATOM 6635 C C . LEU A 1 844 ? 29.538 60.801 -26.699 1.00 10.80 ? 844 LEU A C 1 ATOM 6636 O O . LEU A 1 844 ? 28.851 60.491 -25.701 1.00 9.84 ? 844 LEU A O 1 ATOM 6637 C CB . LEU A 1 844 ? 27.810 61.983 -28.037 1.00 9.75 ? 844 LEU A CB 1 ATOM 6638 C CG . LEU A 1 844 ? 28.427 63.391 -27.903 1.00 10.44 ? 844 LEU A CG 1 ATOM 6639 C CD1 . LEU A 1 844 ? 29.284 63.745 -29.116 1.00 9.12 ? 844 LEU A CD1 1 ATOM 6640 C CD2 . LEU A 1 844 ? 27.329 64.402 -27.794 1.00 10.69 ? 844 LEU A CD2 1 ATOM 6641 N N . THR A 1 845 ? 30.849 61.055 -26.645 1.00 10.05 ? 845 THR A N 1 ATOM 6642 C CA . THR A 1 845 ? 31.579 61.001 -25.363 1.00 9.69 ? 845 THR A CA 1 ATOM 6643 C C . THR A 1 845 ? 32.144 62.389 -25.012 1.00 9.66 ? 845 THR A C 1 ATOM 6644 O O . THR A 1 845 ? 32.805 63.016 -25.839 1.00 10.36 ? 845 THR A O 1 ATOM 6645 C CB . THR A 1 845 ? 32.800 60.023 -25.427 1.00 10.76 ? 845 THR A CB 1 ATOM 6646 O OG1 . THR A 1 845 ? 32.367 58.714 -25.847 1.00 10.32 ? 845 THR A OG1 1 ATOM 6647 C CG2 . THR A 1 845 ? 33.472 59.902 -24.035 1.00 8.19 ? 845 THR A CG2 1 ATOM 6648 N N . LEU A 1 846 ? 31.884 62.868 -23.796 1.00 9.24 ? 846 LEU A N 1 ATOM 6649 C CA . LEU A 1 846 ? 32.441 64.136 -23.362 1.00 8.35 ? 846 LEU A CA 1 ATOM 6650 C C . LEU A 1 846 ? 33.522 63.834 -22.294 1.00 6.99 ? 846 LEU A C 1 ATOM 6651 O O . LEU A 1 846 ? 33.223 63.258 -21.237 1.00 5.05 ? 846 LEU A O 1 ATOM 6652 C CB . LEU A 1 846 ? 31.338 65.019 -22.766 1.00 8.73 ? 846 LEU A CB 1 ATOM 6653 C CG . LEU A 1 846 ? 31.858 66.349 -22.176 1.00 11.92 ? 846 LEU A CG 1 ATOM 6654 C CD1 . LEU A 1 846 ? 32.393 67.232 -23.317 1.00 10.71 ? 846 LEU A CD1 1 ATOM 6655 C CD2 . LEU A 1 846 ? 30.707 67.109 -21.431 1.00 10.34 ? 846 LEU A CD2 1 ATOM 6656 N N . LEU A 1 847 ? 34.776 64.184 -22.584 1.00 7.30 ? 847 LEU A N 1 ATOM 6657 C CA . LEU A 1 847 ? 35.884 63.936 -21.636 1.00 8.91 ? 847 LEU A CA 1 ATOM 6658 C C . LEU A 1 847 ? 36.182 65.257 -20.892 1.00 8.68 ? 847 LEU A C 1 ATOM 6659 O O . LEU A 1 847 ? 36.088 66.322 -21.497 1.00 8.66 ? 847 LEU A O 1 ATOM 6660 C CB . LEU A 1 847 ? 37.148 63.458 -22.363 1.00 6.63 ? 847 LEU A CB 1 ATOM 6661 C CG . LEU A 1 847 ? 37.170 62.045 -22.981 1.00 8.51 ? 847 LEU A CG 1 ATOM 6662 C CD1 . LEU A 1 847 ? 36.456 60.986 -22.077 1.00 6.13 ? 847 LEU A CD1 1 ATOM 6663 C CD2 . LEU A 1 847 ? 36.472 62.136 -24.328 1.00 5.94 ? 847 LEU A CD2 1 ATOM 6664 N N . THR A 1 848 ? 36.533 65.177 -19.603 1.00 8.91 ? 848 THR A N 1 ATOM 6665 C CA . THR A 1 848 ? 36.780 66.379 -18.794 1.00 10.14 ? 848 THR A CA 1 ATOM 6666 C C . THR A 1 848 ? 38.178 66.465 -18.202 1.00 11.68 ? 848 THR A C 1 ATOM 6667 O O . THR A 1 848 ? 38.827 65.434 -17.943 1.00 11.09 ? 848 THR A O 1 ATOM 6668 C CB . THR A 1 848 ? 35.824 66.439 -17.618 1.00 11.58 ? 848 THR A CB 1 ATOM 6669 O OG1 . THR A 1 848 ? 36.271 65.528 -16.591 1.00 14.31 ? 848 THR A OG1 1 ATOM 6670 C CG2 . THR A 1 848 ? 34.426 66.023 -18.053 1.00 11.56 ? 848 THR A CG2 1 ATOM 6671 N N . GLY A 1 849 ? 38.652 67.702 -18.014 1.00 11.06 ? 849 GLY A N 1 ATOM 6672 C CA . GLY A 1 849 ? 39.960 67.900 -17.417 1.00 9.79 ? 849 GLY A CA 1 ATOM 6673 C C . GLY A 1 849 ? 39.754 68.255 -15.945 1.00 10.32 ? 849 GLY A C 1 ATOM 6674 O O . GLY A 1 849 ? 40.669 68.715 -15.261 1.00 9.39 ? 849 GLY A O 1 ATOM 6675 N N . GLN A 1 850 ? 38.543 68.031 -15.444 1.00 9.41 ? 850 GLN A N 1 ATOM 6676 C CA . GLN A 1 850 ? 38.228 68.331 -14.048 1.00 8.72 ? 850 GLN A CA 1 ATOM 6677 C C . GLN A 1 850 ? 36.953 67.591 -13.628 1.00 9.38 ? 850 GLN A C 1 ATOM 6678 O O . GLN A 1 850 ? 36.071 67.347 -14.454 1.00 9.95 ? 850 GLN A O 1 ATOM 6679 C CB . GLN A 1 850 ? 38.019 69.869 -13.856 1.00 9.26 ? 850 GLN A CB 1 ATOM 6680 C CG . GLN A 1 850 ? 36.870 70.475 -14.702 1.00 7.00 ? 850 GLN A CG 1 ATOM 6681 C CD . GLN A 1 850 ? 37.228 70.582 -16.175 1.00 9.08 ? 850 GLN A CD 1 ATOM 6682 O OE1 . GLN A 1 850 ? 38.347 70.982 -16.532 1.00 8.60 ? 850 GLN A OE1 1 ATOM 6683 N NE2 . GLN A 1 850 ? 36.278 70.238 -17.048 1.00 7.33 ? 850 GLN A NE2 1 ATOM 6684 N N . PRO A 1 851 ? 36.838 67.240 -12.333 1.00 8.74 ? 851 PRO A N 1 ATOM 6685 C CA . PRO A 1 851 ? 35.622 66.531 -11.891 1.00 8.86 ? 851 PRO A CA 1 ATOM 6686 C C . PRO A 1 851 ? 34.518 67.547 -11.709 1.00 9.54 ? 851 PRO A C 1 ATOM 6687 O O . PRO A 1 851 ? 34.750 68.605 -11.124 1.00 7.82 ? 851 PRO A O 1 ATOM 6688 C CB . PRO A 1 851 ? 36.031 65.884 -10.554 1.00 7.23 ? 851 PRO A CB 1 ATOM 6689 C CG . PRO A 1 851 ? 37.073 66.894 -9.977 1.00 7.32 ? 851 PRO A CG 1 ATOM 6690 C CD . PRO A 1 851 ? 37.857 67.335 -11.261 1.00 7.18 ? 851 PRO A CD 1 ATOM 6691 N N . LEU A 1 852 ? 33.333 67.223 -12.229 1.00 9.77 ? 852 LEU A N 1 ATOM 6692 C CA . LEU A 1 852 ? 32.154 68.087 -12.141 1.00 10.16 ? 852 LEU A CA 1 ATOM 6693 C C . LEU A 1 852 ? 30.928 67.158 -12.024 1.00 10.10 ? 852 LEU A C 1 ATOM 6694 O O . LEU A 1 852 ? 31.064 65.929 -12.159 1.00 11.45 ? 852 LEU A O 1 ATOM 6695 C CB . LEU A 1 852 ? 32.030 68.945 -13.414 1.00 10.68 ? 852 LEU A CB 1 ATOM 6696 C CG . LEU A 1 852 ? 33.124 70.005 -13.613 1.00 10.21 ? 852 LEU A CG 1 ATOM 6697 C CD1 . LEU A 1 852 ? 33.034 70.635 -15.005 1.00 10.13 ? 852 LEU A CD1 1 ATOM 6698 C CD2 . LEU A 1 852 ? 32.948 71.065 -12.579 1.00 10.18 ? 852 LEU A CD2 1 ATOM 6699 N N . GLY A 1 853 ? 29.746 67.717 -11.793 1.00 7.74 ? 853 GLY A N 1 ATOM 6700 C CA . GLY A 1 853 ? 28.579 66.863 -11.663 1.00 8.85 ? 853 GLY A CA 1 ATOM 6701 C C . GLY A 1 853 ? 27.811 66.837 -12.980 1.00 8.68 ? 853 GLY A C 1 ATOM 6702 O O . GLY A 1 853 ? 27.812 67.823 -13.712 1.00 7.12 ? 853 GLY A O 1 ATOM 6703 N N . GLY A 1 854 ? 27.153 65.731 -13.305 1.00 8.64 ? 854 GLY A N 1 ATOM 6704 C CA . GLY A 1 854 ? 26.425 65.735 -14.570 1.00 9.13 ? 854 GLY A CA 1 ATOM 6705 C C . GLY A 1 854 ? 25.364 64.674 -14.691 1.00 9.47 ? 854 GLY A C 1 ATOM 6706 O O . GLY A 1 854 ? 25.145 63.908 -13.764 1.00 10.01 ? 854 GLY A O 1 ATOM 6707 N N . SER A 1 855 ? 24.714 64.607 -15.850 1.00 10.92 ? 855 SER A N 1 ATOM 6708 C CA . SER A 1 855 ? 23.657 63.629 -16.033 1.00 11.88 ? 855 SER A CA 1 ATOM 6709 C C . SER A 1 855 ? 23.228 63.591 -17.480 1.00 12.09 ? 855 SER A C 1 ATOM 6710 O O . SER A 1 855 ? 23.810 64.270 -18.332 1.00 9.92 ? 855 SER A O 1 ATOM 6711 C CB . SER A 1 855 ? 22.421 64.032 -15.186 1.00 13.09 ? 855 SER A CB 1 ATOM 6712 O OG . SER A 1 855 ? 21.436 62.999 -15.152 1.00 11.23 ? 855 SER A OG 1 ATOM 6713 N N . SER A 1 856 ? 22.178 62.799 -17.720 1.00 12.71 ? 856 SER A N 1 ATOM 6714 C CA . SER A 1 856 ? 21.514 62.682 -19.017 1.00 12.21 ? 856 SER A CA 1 ATOM 6715 C C . SER A 1 856 ? 20.048 62.638 -18.578 1.00 13.06 ? 856 SER A C 1 ATOM 6716 O O . SER A 1 856 ? 19.527 61.555 -18.247 1.00 11.66 ? 856 SER A O 1 ATOM 6717 C CB . SER A 1 856 ? 21.842 61.371 -19.713 1.00 12.12 ? 856 SER A CB 1 ATOM 6718 O OG . SER A 1 856 ? 21.089 61.284 -20.898 1.00 11.45 ? 856 SER A OG 1 ATOM 6719 N N . LEU A 1 857 ? 19.397 63.803 -18.567 1.00 13.03 ? 857 LEU A N 1 ATOM 6720 C CA . LEU A 1 857 ? 18.009 63.910 -18.088 1.00 11.85 ? 857 LEU A CA 1 ATOM 6721 C C . LEU A 1 857 ? 16.948 63.576 -19.133 1.00 11.89 ? 857 LEU A C 1 ATOM 6722 O O . LEU A 1 857 ? 15.764 63.508 -18.818 1.00 14.11 ? 857 LEU A O 1 ATOM 6723 C CB . LEU A 1 857 ? 17.774 65.313 -17.509 1.00 11.32 ? 857 LEU A CB 1 ATOM 6724 C CG . LEU A 1 857 ? 18.662 65.663 -16.307 1.00 10.01 ? 857 LEU A CG 1 ATOM 6725 C CD1 . LEU A 1 857 ? 18.442 67.122 -15.879 1.00 10.94 ? 857 LEU A CD1 1 ATOM 6726 C CD2 . LEU A 1 857 ? 18.342 64.740 -15.140 1.00 11.54 ? 857 LEU A CD2 1 ATOM 6727 N N . ALA A 1 858 ? 17.377 63.371 -20.363 1.00 11.98 ? 858 ALA A N 1 ATOM 6728 C CA . ALA A 1 858 ? 16.487 62.995 -21.442 1.00 12.80 ? 858 ALA A CA 1 ATOM 6729 C C . ALA A 1 858 ? 17.312 62.254 -22.493 1.00 12.94 ? 858 ALA A C 1 ATOM 6730 O O . ALA A 1 858 ? 18.509 62.505 -22.647 1.00 10.61 ? 858 ALA A O 1 ATOM 6731 C CB . ALA A 1 858 ? 15.820 64.247 -22.072 1.00 14.09 ? 858 ALA A CB 1 ATOM 6732 N N . SER A 1 859 ? 16.656 61.338 -23.200 1.00 12.28 ? 859 SER A N 1 ATOM 6733 C CA . SER A 1 859 ? 17.271 60.560 -24.245 1.00 11.79 ? 859 SER A CA 1 ATOM 6734 C C . SER A 1 859 ? 17.983 61.521 -25.199 1.00 11.60 ? 859 SER A C 1 ATOM 6735 O O . SER A 1 859 ? 17.432 62.567 -25.544 1.00 12.02 ? 859 SER A O 1 ATOM 6736 C CB . SER A 1 859 ? 16.183 59.761 -25.012 1.00 11.99 ? 859 SER A CB 1 ATOM 6737 O OG . SER A 1 859 ? 16.741 59.051 -26.108 1.00 11.86 ? 859 SER A OG 1 ATOM 6738 N N . GLY A 1 860 ? 19.206 61.161 -25.579 1.00 9.33 ? 860 GLY A N 1 ATOM 6739 C CA . GLY A 1 860 ? 20.015 61.948 -26.493 1.00 8.94 ? 860 GLY A CA 1 ATOM 6740 C C . GLY A 1 860 ? 20.755 63.129 -25.876 1.00 10.78 ? 860 GLY A C 1 ATOM 6741 O O . GLY A 1 860 ? 21.490 63.850 -26.583 1.00 10.81 ? 860 GLY A O 1 ATOM 6742 N N . GLU A 1 861 ? 20.582 63.325 -24.575 1.00 9.32 ? 861 GLU A N 1 ATOM 6743 C CA . GLU A 1 861 ? 21.217 64.445 -23.875 1.00 11.17 ? 861 GLU A CA 1 ATOM 6744 C C . GLU A 1 861 ? 22.389 64.105 -22.954 1.00 10.65 ? 861 GLU A C 1 ATOM 6745 O O . GLU A 1 861 ? 22.473 63.002 -22.394 1.00 10.14 ? 861 GLU A O 1 ATOM 6746 C CB . GLU A 1 861 ? 20.190 65.179 -23.001 1.00 12.72 ? 861 GLU A CB 1 ATOM 6747 C CG . GLU A 1 861 ? 19.257 66.090 -23.739 1.00 14.47 ? 861 GLU A CG 1 ATOM 6748 C CD . GLU A 1 861 ? 18.291 66.776 -22.811 1.00 16.12 ? 861 GLU A CD 1 ATOM 6749 O OE1 . GLU A 1 861 ? 18.493 66.757 -21.554 1.00 15.31 ? 861 GLU A OE1 1 ATOM 6750 O OE2 . GLU A 1 861 ? 17.321 67.346 -23.348 1.00 15.16 ? 861 GLU A OE2 1 ATOM 6751 N N . LEU A 1 862 ? 23.257 65.095 -22.768 1.00 10.11 ? 862 LEU A N 1 ATOM 6752 C CA . LEU A 1 862 ? 24.384 64.983 -21.837 1.00 10.76 ? 862 LEU A CA 1 ATOM 6753 C C . LEU A 1 862 ? 24.468 66.358 -21.196 1.00 10.92 ? 862 LEU A C 1 ATOM 6754 O O . LEU A 1 862 ? 24.259 67.364 -21.875 1.00 10.19 ? 862 LEU A O 1 ATOM 6755 C CB . LEU A 1 862 ? 25.731 64.705 -22.556 1.00 10.67 ? 862 LEU A CB 1 ATOM 6756 C CG . LEU A 1 862 ? 26.109 63.345 -23.158 1.00 8.95 ? 862 LEU A CG 1 ATOM 6757 C CD1 . LEU A 1 862 ? 27.492 63.389 -23.838 1.00 6.92 ? 862 LEU A CD1 1 ATOM 6758 C CD2 . LEU A 1 862 ? 26.133 62.338 -22.019 1.00 10.61 ? 862 LEU A CD2 1 ATOM 6759 N N . GLU A 1 863 ? 24.740 66.431 -19.899 1.00 10.50 ? 863 GLU A N 1 ATOM 6760 C CA . GLU A 1 863 ? 24.906 67.755 -19.291 1.00 9.53 ? 863 GLU A CA 1 ATOM 6761 C C . GLU A 1 863 ? 25.852 67.668 -18.106 1.00 10.25 ? 863 GLU A C 1 ATOM 6762 O O . GLU A 1 863 ? 25.919 66.644 -17.393 1.00 7.66 ? 863 GLU A O 1 ATOM 6763 C CB . GLU A 1 863 ? 23.579 68.367 -18.856 1.00 11.05 ? 863 GLU A CB 1 ATOM 6764 C CG . GLU A 1 863 ? 22.999 67.862 -17.546 1.00 10.40 ? 863 GLU A CG 1 ATOM 6765 C CD . GLU A 1 863 ? 21.699 68.576 -17.244 1.00 12.61 ? 863 GLU A CD 1 ATOM 6766 O OE1 . GLU A 1 863 ? 21.552 69.123 -16.123 1.00 13.63 ? 863 GLU A OE1 1 ATOM 6767 O OE2 . GLU A 1 863 ? 20.820 68.606 -18.159 1.00 13.74 ? 863 GLU A OE2 1 ATOM 6768 N N . ILE A 1 864 ? 26.578 68.752 -17.906 1.00 9.75 ? 864 ILE A N 1 ATOM 6769 C CA . ILE A 1 864 ? 27.567 68.796 -16.850 1.00 10.30 ? 864 ILE A CA 1 ATOM 6770 C C . ILE A 1 864 ? 27.607 70.210 -16.292 1.00 9.48 ? 864 ILE A C 1 ATOM 6771 O O . ILE A 1 864 ? 27.703 71.177 -17.051 1.00 9.62 ? 864 ILE A O 1 ATOM 6772 C CB . ILE A 1 864 ? 28.926 68.343 -17.443 1.00 11.56 ? 864 ILE A CB 1 ATOM 6773 C CG1 . ILE A 1 864 ? 30.017 68.343 -16.373 1.00 11.96 ? 864 ILE A CG1 1 ATOM 6774 C CG2 . ILE A 1 864 ? 29.300 69.215 -18.662 1.00 11.62 ? 864 ILE A CG2 1 ATOM 6775 C CD1 . ILE A 1 864 ? 31.218 67.464 -16.819 1.00 12.32 ? 864 ILE A CD1 1 ATOM 6776 N N . MET A 1 865 ? 27.501 70.312 -14.973 1.00 8.88 ? 865 MET A N 1 ATOM 6777 C CA . MET A 1 865 ? 27.496 71.594 -14.276 1.00 9.63 ? 865 MET A CA 1 ATOM 6778 C C . MET A 1 865 ? 28.860 72.299 -14.316 1.00 10.20 ? 865 MET A C 1 ATOM 6779 O O . MET A 1 865 ? 29.891 71.675 -14.097 1.00 9.14 ? 865 MET A O 1 ATOM 6780 C CB . MET A 1 865 ? 27.101 71.379 -12.817 1.00 9.27 ? 865 MET A CB 1 ATOM 6781 C CG . MET A 1 865 ? 26.551 72.647 -12.161 1.00 9.11 ? 865 MET A CG 1 ATOM 6782 S SD . MET A 1 865 ? 24.906 73.013 -12.927 1.00 11.34 ? 865 MET A SD 1 ATOM 6783 C CE . MET A 1 865 ? 23.883 71.779 -12.008 1.00 9.19 ? 865 MET A CE 1 ATOM 6784 N N . GLN A 1 866 ? 28.854 73.606 -14.566 1.00 9.79 ? 866 GLN A N 1 ATOM 6785 C CA . GLN A 1 866 ? 30.095 74.373 -14.649 1.00 8.78 ? 866 GLN A CA 1 ATOM 6786 C C . GLN A 1 866 ? 30.497 75.038 -13.317 1.00 8.75 ? 866 GLN A C 1 ATOM 6787 O O . GLN A 1 866 ? 31.672 75.009 -12.935 1.00 8.80 ? 866 GLN A O 1 ATOM 6788 C CB . GLN A 1 866 ? 29.959 75.423 -15.765 1.00 8.84 ? 866 GLN A CB 1 ATOM 6789 C CG . GLN A 1 866 ? 29.625 74.780 -17.127 1.00 9.16 ? 866 GLN A CG 1 ATOM 6790 C CD . GLN A 1 866 ? 30.675 73.753 -17.547 1.00 12.11 ? 866 GLN A CD 1 ATOM 6791 O OE1 . GLN A 1 866 ? 31.814 74.114 -17.849 1.00 11.37 ? 866 GLN A OE1 1 ATOM 6792 N NE2 . GLN A 1 866 ? 30.301 72.472 -17.553 1.00 11.48 ? 866 GLN A NE2 1 ATOM 6793 N N . ASP A 1 867 ? 29.546 75.667 -12.640 1.00 8.35 ? 867 ASP A N 1 ATOM 6794 C CA . ASP A 1 867 ? 29.813 76.302 -11.357 1.00 10.29 ? 867 ASP A CA 1 ATOM 6795 C C . ASP A 1 867 ? 28.457 76.557 -10.697 1.00 11.76 ? 867 ASP A C 1 ATOM 6796 O O . ASP A 1 867 ? 27.408 76.488 -11.371 1.00 12.04 ? 867 ASP A O 1 ATOM 6797 C CB . ASP A 1 867 ? 30.599 77.637 -11.519 1.00 10.61 ? 867 ASP A CB 1 ATOM 6798 C CG . ASP A 1 867 ? 31.311 78.059 -10.232 1.00 11.15 ? 867 ASP A CG 1 ATOM 6799 O OD1 . ASP A 1 867 ? 31.075 77.410 -9.191 1.00 9.17 ? 867 ASP A OD1 1 ATOM 6800 O OD2 . ASP A 1 867 ? 32.096 79.029 -10.252 1.00 11.25 ? 867 ASP A OD2 1 ATOM 6801 N N . ARG A 1 868 ? 28.484 76.791 -9.380 1.00 11.69 ? 868 ARG A N 1 ATOM 6802 C CA . ARG A 1 868 ? 27.279 77.043 -8.596 1.00 12.65 ? 868 ARG A CA 1 ATOM 6803 C C . ARG A 1 868 ? 27.598 78.077 -7.503 1.00 12.62 ? 868 ARG A C 1 ATOM 6804 O O . ARG A 1 868 ? 28.652 78.035 -6.883 1.00 11.58 ? 868 ARG A O 1 ATOM 6805 C CB . ARG A 1 868 ? 26.769 75.743 -7.952 1.00 11.38 ? 868 ARG A CB 1 ATOM 6806 C CG . ARG A 1 868 ? 27.813 74.972 -7.139 1.00 12.14 ? 868 ARG A CG 1 ATOM 6807 C CD . ARG A 1 868 ? 27.516 73.441 -7.215 1.00 10.96 ? 868 ARG A CD 1 ATOM 6808 N NE . ARG A 1 868 ? 26.148 73.140 -6.814 1.00 8.88 ? 868 ARG A NE 1 ATOM 6809 C CZ . ARG A 1 868 ? 25.787 72.865 -5.565 1.00 10.57 ? 868 ARG A CZ 1 ATOM 6810 N NH1 . ARG A 1 868 ? 26.698 72.828 -4.579 1.00 11.41 ? 868 ARG A NH1 1 ATOM 6811 N NH2 . ARG A 1 868 ? 24.513 72.653 -5.281 1.00 8.62 ? 868 ARG A NH2 1 ATOM 6812 N N . ARG A 1 869 ? 26.681 79.004 -7.279 1.00 11.58 ? 869 ARG A N 1 ATOM 6813 C CA . ARG A 1 869 ? 26.886 80.050 -6.277 1.00 12.12 ? 869 ARG A CA 1 ATOM 6814 C C . ARG A 1 869 ? 25.619 80.032 -5.463 1.00 12.81 ? 869 ARG A C 1 ATOM 6815 O O . ARG A 1 869 ? 24.542 80.305 -5.970 1.00 12.25 ? 869 ARG A O 1 ATOM 6816 C CB . ARG A 1 869 ? 27.091 81.397 -6.965 1.00 11.99 ? 869 ARG A CB 1 ATOM 6817 C CG . ARG A 1 869 ? 27.253 82.579 -6.013 1.00 12.83 ? 869 ARG A CG 1 ATOM 6818 C CD . ARG A 1 869 ? 27.710 83.815 -6.784 1.00 14.50 ? 869 ARG A CD 1 ATOM 6819 N NE . ARG A 1 869 ? 27.833 84.998 -5.928 1.00 16.10 ? 869 ARG A NE 1 ATOM 6820 C CZ . ARG A 1 869 ? 28.962 85.416 -5.360 1.00 16.94 ? 869 ARG A CZ 1 ATOM 6821 N NH1 . ARG A 1 869 ? 30.093 84.753 -5.555 1.00 16.49 ? 869 ARG A NH1 1 ATOM 6822 N NH2 . ARG A 1 869 ? 28.960 86.511 -4.581 1.00 16.30 ? 869 ARG A NH2 1 ATOM 6823 N N . LEU A 1 870 ? 25.752 79.685 -4.194 1.00 13.85 ? 870 LEU A N 1 ATOM 6824 C CA . LEU A 1 870 ? 24.589 79.553 -3.337 1.00 15.37 ? 870 LEU A CA 1 ATOM 6825 C C . LEU A 1 870 ? 24.691 80.402 -2.066 1.00 15.79 ? 870 LEU A C 1 ATOM 6826 O O . LEU A 1 870 ? 25.683 80.346 -1.307 1.00 14.77 ? 870 LEU A O 1 ATOM 6827 C CB . LEU A 1 870 ? 24.416 78.074 -2.998 1.00 15.50 ? 870 LEU A CB 1 ATOM 6828 C CG . LEU A 1 870 ? 24.482 77.275 -4.313 1.00 17.94 ? 870 LEU A CG 1 ATOM 6829 C CD1 . LEU A 1 870 ? 25.103 75.971 -4.035 1.00 18.88 ? 870 LEU A CD1 1 ATOM 6830 C CD2 . LEU A 1 870 ? 23.099 77.105 -4.965 1.00 18.07 ? 870 LEU A CD2 1 ATOM 6831 N N . ALA A 1 871 ? 23.636 81.173 -1.834 1.00 16.54 ? 871 ALA A N 1 ATOM 6832 C CA . ALA A 1 871 ? 23.602 82.077 -0.702 1.00 18.10 ? 871 ALA A CA 1 ATOM 6833 C C . ALA A 1 871 ? 23.354 81.388 0.630 1.00 19.21 ? 871 ALA A C 1 ATOM 6834 O O . ALA A 1 871 ? 23.754 81.913 1.657 1.00 20.24 ? 871 ALA A O 1 ATOM 6835 C CB . ALA A 1 871 ? 22.518 83.161 -0.935 1.00 19.23 ? 871 ALA A CB 1 ATOM 6836 N N . SER A 1 872 ? 22.703 80.220 0.625 1.00 18.78 ? 872 SER A N 1 ATOM 6837 C CA . SER A 1 872 ? 22.381 79.551 1.897 1.00 18.65 ? 872 SER A CA 1 ATOM 6838 C C . SER A 1 872 ? 23.208 78.354 2.298 1.00 17.17 ? 872 SER A C 1 ATOM 6839 O O . SER A 1 872 ? 23.808 77.693 1.474 1.00 15.65 ? 872 SER A O 1 ATOM 6840 C CB . SER A 1 872 ? 20.918 79.089 1.901 1.00 20.94 ? 872 SER A CB 1 ATOM 6841 O OG . SER A 1 872 ? 20.037 80.157 1.586 1.00 23.65 ? 872 SER A OG 1 ATOM 6842 N N . ASP A 1 873 ? 23.214 78.089 3.597 1.00 16.63 ? 873 ASP A N 1 ATOM 6843 C CA . ASP A 1 873 ? 23.894 76.921 4.149 1.00 16.15 ? 873 ASP A CA 1 ATOM 6844 C C . ASP A 1 873 ? 22.888 75.775 3.979 1.00 14.87 ? 873 ASP A C 1 ATOM 6845 O O . ASP A 1 873 ? 21.685 76.017 4.027 1.00 14.37 ? 873 ASP A O 1 ATOM 6846 C CB . ASP A 1 873 ? 24.156 77.114 5.624 1.00 15.20 ? 873 ASP A CB 1 ATOM 6847 C CG . ASP A 1 873 ? 24.663 75.862 6.274 1.00 16.29 ? 873 ASP A CG 1 ATOM 6848 O OD1 . ASP A 1 873 ? 23.975 75.358 7.168 1.00 15.17 ? 873 ASP A OD1 1 ATOM 6849 O OD2 . ASP A 1 873 ? 25.751 75.365 5.880 1.00 16.00 ? 873 ASP A OD2 1 ATOM 6850 N N . ASP A 1 874 ? 23.358 74.545 3.792 1.00 14.89 ? 874 ASP A N 1 ATOM 6851 C CA . ASP A 1 874 ? 22.446 73.415 3.612 1.00 14.54 ? 874 ASP A CA 1 ATOM 6852 C C . ASP A 1 874 ? 22.385 72.469 4.826 1.00 15.81 ? 874 ASP A C 1 ATOM 6853 O O . ASP A 1 874 ? 22.139 71.274 4.699 1.00 15.44 ? 874 ASP A O 1 ATOM 6854 C CB . ASP A 1 874 ? 22.772 72.648 2.322 1.00 14.03 ? 874 ASP A CB 1 ATOM 6855 C CG . ASP A 1 874 ? 24.286 72.349 2.155 1.00 15.84 ? 874 ASP A CG 1 ATOM 6856 O OD1 . ASP A 1 874 ? 25.108 72.643 3.084 1.00 14.86 ? 874 ASP A OD1 1 ATOM 6857 O OD2 . ASP A 1 874 ? 24.639 71.807 1.076 1.00 14.34 ? 874 ASP A OD2 1 ATOM 6858 N N . GLU A 1 875 ? 22.643 73.027 6.000 1.00 16.04 ? 875 GLU A N 1 ATOM 6859 C CA . GLU A 1 875 ? 22.512 72.299 7.258 1.00 17.14 ? 875 GLU A CA 1 ATOM 6860 C C . GLU A 1 875 ? 23.271 71.004 7.466 1.00 16.72 ? 875 GLU A C 1 ATOM 6861 O O . GLU A 1 875 ? 22.750 70.086 8.113 1.00 14.98 ? 875 GLU A O 1 ATOM 6862 C CB . GLU A 1 875 ? 21.019 72.032 7.520 1.00 20.19 ? 875 GLU A CB 1 ATOM 6863 C CG . GLU A 1 875 ? 20.104 73.250 7.260 1.00 25.56 ? 875 GLU A CG 1 ATOM 6864 C CD . GLU A 1 875 ? 18.670 73.020 7.728 1.00 28.90 ? 875 GLU A CD 1 ATOM 6865 O OE1 . GLU A 1 875 ? 18.400 73.207 8.932 1.00 31.65 ? 875 GLU A OE1 1 ATOM 6866 O OE2 . GLU A 1 875 ? 17.819 72.626 6.904 1.00 31.87 ? 875 GLU A OE2 1 ATOM 6867 N N . ARG A 1 876 ? 24.496 70.913 6.949 1.00 15.16 ? 876 ARG A N 1 ATOM 6868 C CA . ARG A 1 876 ? 25.278 69.710 7.172 1.00 12.73 ? 876 ARG A CA 1 ATOM 6869 C C . ARG A 1 876 ? 26.509 70.095 7.997 1.00 13.13 ? 876 ARG A C 1 ATOM 6870 O O . ARG A 1 876 ? 27.470 69.328 8.120 1.00 11.46 ? 876 ARG A O 1 ATOM 6871 C CB . ARG A 1 876 ? 25.670 69.058 5.825 1.00 14.12 ? 876 ARG A CB 1 ATOM 6872 C CG . ARG A 1 876 ? 24.475 68.436 5.029 1.00 9.31 ? 876 ARG A CG 1 ATOM 6873 C CD . ARG A 1 876 ? 23.661 67.468 5.884 1.00 10.26 ? 876 ARG A CD 1 ATOM 6874 N NE . ARG A 1 876 ? 22.545 66.797 5.202 1.00 10.11 ? 876 ARG A NE 1 ATOM 6875 C CZ . ARG A 1 876 ? 21.350 67.354 4.949 1.00 11.85 ? 876 ARG A CZ 1 ATOM 6876 N NH1 . ARG A 1 876 ? 21.112 68.616 5.303 1.00 7.10 ? 876 ARG A NH1 1 ATOM 6877 N NH2 . ARG A 1 876 ? 20.370 66.616 4.412 1.00 10.56 ? 876 ARG A NH2 1 ATOM 6878 N N . GLY A 1 877 ? 26.477 71.305 8.555 1.00 13.12 ? 877 GLY A N 1 ATOM 6879 C CA . GLY A 1 877 ? 27.569 71.770 9.410 1.00 12.90 ? 877 GLY A CA 1 ATOM 6880 C C . GLY A 1 877 ? 28.564 72.801 8.865 1.00 14.01 ? 877 GLY A C 1 ATOM 6881 O O . GLY A 1 877 ? 29.334 73.395 9.655 1.00 14.47 ? 877 GLY A O 1 ATOM 6882 N N . LEU A 1 878 ? 28.548 73.063 7.555 1.00 13.29 ? 878 LEU A N 1 ATOM 6883 C CA . LEU A 1 878 ? 29.515 74.002 6.997 1.00 13.28 ? 878 LEU A CA 1 ATOM 6884 C C . LEU A 1 878 ? 29.287 75.423 7.509 1.00 15.07 ? 878 LEU A C 1 ATOM 6885 O O . LEU A 1 878 ? 30.249 76.182 7.714 1.00 14.61 ? 878 LEU A O 1 ATOM 6886 C CB . LEU A 1 878 ? 29.491 73.930 5.460 1.00 13.22 ? 878 LEU A CB 1 ATOM 6887 C CG . LEU A 1 878 ? 30.341 74.947 4.689 1.00 13.62 ? 878 LEU A CG 1 ATOM 6888 C CD1 . LEU A 1 878 ? 31.827 74.828 5.150 1.00 12.98 ? 878 LEU A CD1 1 ATOM 6889 C CD2 . LEU A 1 878 ? 30.210 74.676 3.191 1.00 11.07 ? 878 LEU A CD2 1 ATOM 6890 N N . GLY A 1 879 ? 28.024 75.776 7.745 1.00 14.39 ? 879 GLY A N 1 ATOM 6891 C CA . GLY A 1 879 ? 27.715 77.094 8.284 1.00 16.09 ? 879 GLY A CA 1 ATOM 6892 C C . GLY A 1 879 ? 27.866 78.264 7.329 1.00 16.89 ? 879 GLY A C 1 ATOM 6893 O O . GLY A 1 879 ? 28.020 79.412 7.756 1.00 16.56 ? 879 GLY A O 1 ATOM 6894 N N . GLN A 1 880 ? 27.846 77.989 6.028 1.00 15.61 ? 880 GLN A N 1 ATOM 6895 C CA . GLN A 1 880 ? 27.944 79.065 5.057 1.00 15.86 ? 880 GLN A CA 1 ATOM 6896 C C . GLN A 1 880 ? 27.492 78.542 3.695 1.00 16.08 ? 880 GLN A C 1 ATOM 6897 O O . GLN A 1 880 ? 27.372 77.319 3.495 1.00 15.70 ? 880 GLN A O 1 ATOM 6898 C CB . GLN A 1 880 ? 29.399 79.595 4.965 1.00 16.31 ? 880 GLN A CB 1 ATOM 6899 C CG . GLN A 1 880 ? 30.406 78.587 4.308 1.00 14.60 ? 880 GLN A CG 1 ATOM 6900 C CD . GLN A 1 880 ? 31.741 79.232 3.899 1.00 13.46 ? 880 GLN A CD 1 ATOM 6901 O OE1 . GLN A 1 880 ? 32.589 79.504 4.740 1.00 12.66 ? 880 GLN A OE1 1 ATOM 6902 N NE2 . GLN A 1 880 ? 31.918 79.485 2.599 1.00 14.90 ? 880 GLN A NE2 1 ATOM 6903 N N . GLY A 1 881 ? 27.212 79.466 2.780 1.00 15.67 ? 881 GLY A N 1 ATOM 6904 C CA . GLY A 1 881 ? 26.834 79.069 1.440 1.00 15.36 ? 881 GLY A CA 1 ATOM 6905 C C . GLY A 1 881 ? 28.123 79.000 0.616 1.00 16.36 ? 881 GLY A C 1 ATOM 6906 O O . GLY A 1 881 ? 29.229 78.841 1.163 1.00 16.61 ? 881 GLY A O 1 ATOM 6907 N N . VAL A 1 882 ? 27.984 79.105 -0.700 1.00 14.30 ? 882 VAL A N 1 ATOM 6908 C CA . VAL A 1 882 ? 29.130 79.097 -1.587 1.00 14.29 ? 882 VAL A CA 1 ATOM 6909 C C . VAL A 1 882 ? 29.105 80.411 -2.345 1.00 13.72 ? 882 VAL A C 1 ATOM 6910 O O . VAL A 1 882 ? 28.394 80.546 -3.344 1.00 12.57 ? 882 VAL A O 1 ATOM 6911 C CB . VAL A 1 882 ? 29.044 77.920 -2.562 1.00 13.52 ? 882 VAL A CB 1 ATOM 6912 C CG1 . VAL A 1 882 ? 30.181 77.994 -3.582 1.00 13.05 ? 882 VAL A CG1 1 ATOM 6913 C CG2 . VAL A 1 882 ? 29.086 76.622 -1.749 1.00 13.99 ? 882 VAL A CG2 1 ATOM 6914 N N . LEU A 1 883 ? 29.870 81.379 -1.854 1.00 15.02 ? 883 LEU A N 1 ATOM 6915 C CA . LEU A 1 883 ? 29.905 82.690 -2.483 1.00 16.24 ? 883 LEU A CA 1 ATOM 6916 C C . LEU A 1 883 ? 31.323 83.147 -2.776 1.00 16.26 ? 883 LEU A C 1 ATOM 6917 O O . LEU A 1 883 ? 31.561 84.342 -2.973 1.00 18.46 ? 883 LEU A O 1 ATOM 6918 C CB . LEU A 1 883 ? 29.220 83.710 -1.574 1.00 17.49 ? 883 LEU A CB 1 ATOM 6919 C CG . LEU A 1 883 ? 27.747 83.441 -1.244 1.00 18.13 ? 883 LEU A CG 1 ATOM 6920 C CD1 . LEU A 1 883 ? 27.250 84.477 -0.211 1.00 17.16 ? 883 LEU A CD1 1 ATOM 6921 C CD2 . LEU A 1 883 ? 26.924 83.538 -2.525 1.00 17.71 ? 883 LEU A CD2 1 ATOM 6922 N N . ASP A 1 884 ? 32.263 82.207 -2.798 1.00 14.40 ? 884 ASP A N 1 ATOM 6923 C CA . ASP A 1 884 ? 33.665 82.521 -3.074 1.00 14.06 ? 884 ASP A CA 1 ATOM 6924 C C . ASP A 1 884 ? 34.133 82.085 -4.471 1.00 13.68 ? 884 ASP A C 1 ATOM 6925 O O . ASP A 1 884 ? 35.308 81.798 -4.683 1.00 13.27 ? 884 ASP A O 1 ATOM 6926 C CB . ASP A 1 884 ? 34.565 81.896 -2.018 1.00 14.25 ? 884 ASP A CB 1 ATOM 6927 C CG . ASP A 1 884 ? 34.332 80.397 -1.844 1.00 16.73 ? 884 ASP A CG 1 ATOM 6928 O OD1 . ASP A 1 884 ? 34.997 79.828 -0.944 1.00 17.96 ? 884 ASP A OD1 1 ATOM 6929 O OD2 . ASP A 1 884 ? 33.499 79.793 -2.575 1.00 17.08 ? 884 ASP A OD2 1 ATOM 6930 N N . ASN A 1 885 ? 33.201 82.054 -5.415 1.00 12.92 ? 885 ASN A N 1 ATOM 6931 C CA . ASN A 1 885 ? 33.498 81.665 -6.777 1.00 12.83 ? 885 ASN A CA 1 ATOM 6932 C C . ASN A 1 885 ? 34.556 82.535 -7.391 1.00 13.94 ? 885 ASN A C 1 ATOM 6933 O O . ASN A 1 885 ? 34.680 83.713 -7.044 1.00 14.02 ? 885 ASN A O 1 ATOM 6934 C CB . ASN A 1 885 ? 32.253 81.781 -7.657 1.00 12.68 ? 885 ASN A CB 1 ATOM 6935 C CG . ASN A 1 885 ? 31.019 81.179 -7.004 1.00 13.31 ? 885 ASN A CG 1 ATOM 6936 O OD1 . ASN A 1 885 ? 30.431 81.767 -6.077 1.00 12.69 ? 885 ASN A OD1 1 ATOM 6937 N ND2 . ASN A 1 885 ? 30.638 80.002 -7.461 1.00 11.35 ? 885 ASN A ND2 1 ATOM 6938 N N . LYS A 1 886 ? 35.312 81.948 -8.313 1.00 12.69 ? 886 LYS A N 1 ATOM 6939 C CA . LYS A 1 886 ? 36.299 82.690 -9.034 1.00 14.36 ? 886 LYS A CA 1 ATOM 6940 C C . LYS A 1 886 ? 36.416 82.099 -10.441 1.00 14.46 ? 886 LYS A C 1 ATOM 6941 O O . LYS A 1 886 ? 36.065 80.929 -10.701 1.00 14.52 ? 886 LYS A O 1 ATOM 6942 C CB . LYS A 1 886 ? 37.641 82.670 -8.290 1.00 16.61 ? 886 LYS A CB 1 ATOM 6943 C CG . LYS A 1 886 ? 38.142 81.285 -8.010 1.00 18.84 ? 886 LYS A CG 1 ATOM 6944 C CD . LYS A 1 886 ? 39.232 81.279 -6.939 1.00 22.86 ? 886 LYS A CD 1 ATOM 6945 C CE . LYS A 1 886 ? 40.485 81.967 -7.403 1.00 20.16 ? 886 LYS A CE 1 ATOM 6946 N NZ . LYS A 1 886 ? 41.671 81.517 -6.597 1.00 22.07 ? 886 LYS A NZ 1 ATOM 6947 N N . PRO A 1 887 ? 36.899 82.908 -11.385 1.00 12.97 ? 887 PRO A N 1 ATOM 6948 C CA . PRO A 1 887 ? 37.051 82.450 -12.761 1.00 12.09 ? 887 PRO A CA 1 ATOM 6949 C C . PRO A 1 887 ? 37.803 81.119 -12.876 1.00 11.13 ? 887 PRO A C 1 ATOM 6950 O O . PRO A 1 887 ? 38.858 80.944 -12.290 1.00 10.79 ? 887 PRO A O 1 ATOM 6951 C CB . PRO A 1 887 ? 37.852 83.582 -13.405 1.00 13.48 ? 887 PRO A CB 1 ATOM 6952 C CG . PRO A 1 887 ? 37.391 84.803 -12.651 1.00 12.82 ? 887 PRO A CG 1 ATOM 6953 C CD . PRO A 1 887 ? 37.366 84.303 -11.226 1.00 14.02 ? 887 PRO A CD 1 ATOM 6954 N N . VAL A 1 888 ? 37.249 80.179 -13.620 1.00 9.92 ? 888 VAL A N 1 ATOM 6955 C CA . VAL A 1 888 ? 37.932 78.927 -13.819 1.00 10.24 ? 888 VAL A CA 1 ATOM 6956 C C . VAL A 1 888 ? 37.798 78.569 -15.294 1.00 10.95 ? 888 VAL A C 1 ATOM 6957 O O . VAL A 1 888 ? 36.782 78.910 -15.948 1.00 11.21 ? 888 VAL A O 1 ATOM 6958 C CB . VAL A 1 888 ? 37.342 77.779 -12.918 1.00 11.39 ? 888 VAL A CB 1 ATOM 6959 C CG1 . VAL A 1 888 ? 35.797 77.694 -13.087 1.00 10.47 ? 888 VAL A CG1 1 ATOM 6960 C CG2 . VAL A 1 888 ? 38.017 76.424 -13.291 1.00 8.90 ? 888 VAL A CG2 1 ATOM 6961 N N . LEU A 1 889 ? 38.824 77.900 -15.798 1.00 10.07 ? 889 LEU A N 1 ATOM 6962 C CA . LEU A 1 889 ? 38.881 77.450 -17.182 1.00 9.94 ? 889 LEU A CA 1 ATOM 6963 C C . LEU A 1 889 ? 38.682 75.952 -17.208 1.00 9.62 ? 889 LEU A C 1 ATOM 6964 O O . LEU A 1 889 ? 39.599 75.190 -16.870 1.00 8.11 ? 889 LEU A O 1 ATOM 6965 C CB . LEU A 1 889 ? 40.242 77.760 -17.827 1.00 9.67 ? 889 LEU A CB 1 ATOM 6966 C CG . LEU A 1 889 ? 40.263 77.386 -19.336 1.00 10.10 ? 889 LEU A CG 1 ATOM 6967 C CD1 . LEU A 1 889 ? 39.493 78.440 -20.173 1.00 10.25 ? 889 LEU A CD1 1 ATOM 6968 C CD2 . LEU A 1 889 ? 41.712 77.249 -19.830 1.00 10.85 ? 889 LEU A CD2 1 ATOM 6969 N N . HIS A 1 890 ? 37.471 75.525 -17.562 1.00 9.31 ? 890 HIS A N 1 ATOM 6970 C CA . HIS A 1 890 ? 37.172 74.103 -17.664 1.00 9.29 ? 890 HIS A CA 1 ATOM 6971 C C . HIS A 1 890 ? 37.540 73.653 -19.068 1.00 9.74 ? 890 HIS A C 1 ATOM 6972 O O . HIS A 1 890 ? 37.281 74.363 -20.023 1.00 10.97 ? 890 HIS A O 1 ATOM 6973 C CB . HIS A 1 890 ? 35.679 73.862 -17.461 1.00 9.45 ? 890 HIS A CB 1 ATOM 6974 C CG . HIS A 1 890 ? 35.218 74.081 -16.059 1.00 9.04 ? 890 HIS A CG 1 ATOM 6975 N ND1 . HIS A 1 890 ? 35.969 73.705 -14.967 1.00 7.43 ? 890 HIS A ND1 1 ATOM 6976 C CD2 . HIS A 1 890 ? 34.047 74.544 -15.571 1.00 7.29 ? 890 HIS A CD2 1 ATOM 6977 C CE1 . HIS A 1 890 ? 35.272 73.915 -13.866 1.00 8.94 ? 890 HIS A CE1 1 ATOM 6978 N NE2 . HIS A 1 890 ? 34.102 74.424 -14.206 1.00 9.20 ? 890 HIS A NE2 1 ATOM 6979 N N . ILE A 1 891 ? 38.131 72.473 -19.203 1.00 9.86 ? 891 ILE A N 1 ATOM 6980 C CA . ILE A 1 891 ? 38.498 71.970 -20.518 1.00 8.70 ? 891 ILE A CA 1 ATOM 6981 C C . ILE A 1 891 ? 37.870 70.598 -20.760 1.00 9.06 ? 891 ILE A C 1 ATOM 6982 O O . ILE A 1 891 ? 37.628 69.842 -19.818 1.00 8.69 ? 891 ILE A O 1 ATOM 6983 C CB . ILE A 1 891 ? 40.029 71.898 -20.677 1.00 7.64 ? 891 ILE A CB 1 ATOM 6984 C CG1 . ILE A 1 891 ? 40.618 70.914 -19.664 1.00 8.76 ? 891 ILE A CG1 1 ATOM 6985 C CG2 . ILE A 1 891 ? 40.624 73.299 -20.445 1.00 7.39 ? 891 ILE A CG2 1 ATOM 6986 C CD1 . ILE A 1 891 ? 42.170 70.725 -19.804 1.00 11.18 ? 891 ILE A CD1 1 ATOM 6987 N N . TYR A 1 892 ? 37.613 70.293 -22.031 1.00 7.86 ? 892 TYR A N 1 ATOM 6988 C CA . TYR A 1 892 ? 36.990 69.034 -22.421 1.00 9.18 ? 892 TYR A CA 1 ATOM 6989 C C . TYR A 1 892 ? 37.417 68.639 -23.814 1.00 9.32 ? 892 TYR A C 1 ATOM 6990 O O . TYR A 1 892 ? 38.031 69.418 -24.531 1.00 9.14 ? 892 TYR A O 1 ATOM 6991 C CB . TYR A 1 892 ? 35.450 69.164 -22.508 1.00 7.68 ? 892 TYR A CB 1 ATOM 6992 C CG . TYR A 1 892 ? 34.794 69.830 -21.347 1.00 8.33 ? 892 TYR A CG 1 ATOM 6993 C CD1 . TYR A 1 892 ? 34.798 71.235 -21.216 1.00 7.45 ? 892 TYR A CD1 1 ATOM 6994 C CD2 . TYR A 1 892 ? 34.162 69.066 -20.354 1.00 7.60 ? 892 TYR A CD2 1 ATOM 6995 C CE1 . TYR A 1 892 ? 34.183 71.857 -20.120 1.00 8.26 ? 892 TYR A CE1 1 ATOM 6996 C CE2 . TYR A 1 892 ? 33.552 69.679 -19.254 1.00 7.56 ? 892 TYR A CE2 1 ATOM 6997 C CZ . TYR A 1 892 ? 33.564 71.068 -19.139 1.00 8.44 ? 892 TYR A CZ 1 ATOM 6998 O OH . TYR A 1 892 ? 32.978 71.648 -18.031 1.00 9.84 ? 892 TYR A OH 1 ATOM 6999 N N . ARG A 1 893 ? 37.083 67.402 -24.178 1.00 10.26 ? 893 ARG A N 1 ATOM 7000 C CA . ARG A 1 893 ? 37.289 66.926 -25.551 1.00 10.44 ? 893 ARG A CA 1 ATOM 7001 C C . ARG A 1 893 ? 35.897 66.334 -25.868 1.00 10.83 ? 893 ARG A C 1 ATOM 7002 O O . ARG A 1 893 ? 35.299 65.680 -25.013 1.00 10.40 ? 893 ARG A O 1 ATOM 7003 C CB . ARG A 1 893 ? 38.360 65.844 -25.671 1.00 9.93 ? 893 ARG A CB 1 ATOM 7004 C CG . ARG A 1 893 ? 39.829 66.336 -25.547 1.00 10.83 ? 893 ARG A CG 1 ATOM 7005 C CD . ARG A 1 893 ? 40.196 67.414 -26.599 1.00 10.47 ? 893 ARG A CD 1 ATOM 7006 N NE . ARG A 1 893 ? 40.211 66.898 -27.970 1.00 12.00 ? 893 ARG A NE 1 ATOM 7007 C CZ . ARG A 1 893 ? 41.101 66.024 -28.452 1.00 12.72 ? 893 ARG A CZ 1 ATOM 7008 N NH1 . ARG A 1 893 ? 42.069 65.529 -27.681 1.00 13.32 ? 893 ARG A NH1 1 ATOM 7009 N NH2 . ARG A 1 893 ? 41.053 65.674 -29.723 1.00 12.56 ? 893 ARG A NH2 1 ATOM 7010 N N . LEU A 1 894 ? 35.380 66.594 -27.064 1.00 10.43 ? 894 LEU A N 1 ATOM 7011 C CA . LEU A 1 894 ? 34.046 66.095 -27.435 1.00 11.57 ? 894 LEU A CA 1 ATOM 7012 C C . LEU A 1 894 ? 34.228 65.112 -28.610 1.00 10.56 ? 894 LEU A C 1 ATOM 7013 O O . LEU A 1 894 ? 34.632 65.497 -29.707 1.00 9.90 ? 894 LEU A O 1 ATOM 7014 C CB . LEU A 1 894 ? 33.123 67.274 -27.816 1.00 11.07 ? 894 LEU A CB 1 ATOM 7015 C CG . LEU A 1 894 ? 31.655 66.872 -28.152 1.00 12.75 ? 894 LEU A CG 1 ATOM 7016 C CD1 . LEU A 1 894 ? 30.926 66.407 -26.892 1.00 12.46 ? 894 LEU A CD1 1 ATOM 7017 C CD2 . LEU A 1 894 ? 30.892 68.067 -28.769 1.00 11.97 ? 894 LEU A CD2 1 ATOM 7018 N N . VAL A 1 895 ? 33.929 63.839 -28.356 1.00 11.27 ? 895 VAL A N 1 ATOM 7019 C CA . VAL A 1 895 ? 34.109 62.792 -29.349 1.00 11.99 ? 895 VAL A CA 1 ATOM 7020 C C . VAL A 1 895 ? 32.811 62.187 -29.881 1.00 11.10 ? 895 VAL A C 1 ATOM 7021 O O . VAL A 1 895 ? 32.133 61.484 -29.166 1.00 10.82 ? 895 VAL A O 1 ATOM 7022 C CB . VAL A 1 895 ? 34.913 61.603 -28.760 1.00 12.12 ? 895 VAL A CB 1 ATOM 7023 C CG1 . VAL A 1 895 ? 35.238 60.622 -29.872 1.00 12.69 ? 895 VAL A CG1 1 ATOM 7024 C CG2 . VAL A 1 895 ? 36.168 62.098 -28.039 1.00 14.25 ? 895 VAL A CG2 1 ATOM 7025 N N . LEU A 1 896 ? 32.485 62.452 -31.139 1.00 12.05 ? 896 LEU A N 1 ATOM 7026 C CA . LEU A 1 896 ? 31.291 61.866 -31.746 1.00 10.99 ? 896 LEU A CA 1 ATOM 7027 C C . LEU A 1 896 ? 31.869 60.719 -32.581 1.00 10.94 ? 896 LEU A C 1 ATOM 7028 O O . LEU A 1 896 ? 32.793 60.950 -33.363 1.00 10.03 ? 896 LEU A O 1 ATOM 7029 C CB . LEU A 1 896 ? 30.585 62.855 -32.686 1.00 9.73 ? 896 LEU A CB 1 ATOM 7030 C CG . LEU A 1 896 ? 29.440 62.222 -33.523 1.00 11.23 ? 896 LEU A CG 1 ATOM 7031 C CD1 . LEU A 1 896 ? 28.191 61.987 -32.645 1.00 11.75 ? 896 LEU A CD1 1 ATOM 7032 C CD2 . LEU A 1 896 ? 29.072 63.144 -34.693 1.00 13.91 ? 896 LEU A CD2 1 ATOM 7033 N N . GLU A 1 897 ? 31.347 59.503 -32.420 1.00 10.40 ? 897 GLU A N 1 ATOM 7034 C CA . GLU A 1 897 ? 31.872 58.365 -33.190 1.00 12.99 ? 897 GLU A CA 1 ATOM 7035 C C . GLU A 1 897 ? 30.785 57.354 -33.553 1.00 13.28 ? 897 GLU A C 1 ATOM 7036 O O . GLU A 1 897 ? 29.773 57.266 -32.877 1.00 14.23 ? 897 GLU A O 1 ATOM 7037 C CB . GLU A 1 897 ? 32.916 57.564 -32.384 1.00 12.46 ? 897 GLU A CB 1 ATOM 7038 C CG . GLU A 1 897 ? 33.760 58.310 -31.413 1.00 15.32 ? 897 GLU A CG 1 ATOM 7039 C CD . GLU A 1 897 ? 34.424 57.372 -30.373 1.00 11.99 ? 897 GLU A CD 1 ATOM 7040 O OE1 . GLU A 1 897 ? 33.827 57.092 -29.297 1.00 13.19 ? 897 GLU A OE1 1 ATOM 7041 O OE2 . GLU A 1 897 ? 35.551 56.943 -30.657 1.00 12.08 ? 897 GLU A OE2 1 ATOM 7042 N N . LYS A 1 898 ? 31.023 56.569 -34.599 1.00 14.64 ? 898 LYS A N 1 ATOM 7043 C CA . LYS A 1 898 ? 30.098 55.504 -34.991 1.00 16.65 ? 898 LYS A CA 1 ATOM 7044 C C . LYS A 1 898 ? 30.587 54.269 -34.196 1.00 17.39 ? 898 LYS A C 1 ATOM 7045 O O . LYS A 1 898 ? 31.792 53.982 -34.169 1.00 18.43 ? 898 LYS A O 1 ATOM 7046 C CB . LYS A 1 898 ? 30.187 55.231 -36.502 1.00 17.75 ? 898 LYS A CB 1 ATOM 7047 C CG . LYS A 1 898 ? 29.780 56.416 -37.384 1.00 21.30 ? 898 LYS A CG 1 ATOM 7048 C CD . LYS A 1 898 ? 28.432 57.011 -36.918 1.00 25.90 ? 898 LYS A CD 1 ATOM 7049 C CE . LYS A 1 898 ? 27.187 56.238 -37.417 1.00 27.91 ? 898 LYS A CE 1 ATOM 7050 N NZ . LYS A 1 898 ? 27.281 54.765 -37.243 1.00 30.04 ? 898 LYS A NZ 1 ATOM 7051 N N . VAL A 1 899 ? 29.680 53.553 -33.544 1.00 16.16 ? 899 VAL A N 1 ATOM 7052 C CA . VAL A 1 899 ? 30.084 52.391 -32.748 1.00 15.61 ? 899 VAL A CA 1 ATOM 7053 C C . VAL A 1 899 ? 29.374 51.109 -33.199 1.00 15.61 ? 899 VAL A C 1 ATOM 7054 O O . VAL A 1 899 ? 29.430 50.082 -32.518 1.00 12.65 ? 899 VAL A O 1 ATOM 7055 C CB . VAL A 1 899 ? 29.763 52.625 -31.241 1.00 14.05 ? 899 VAL A CB 1 ATOM 7056 C CG1 . VAL A 1 899 ? 30.713 53.698 -30.666 1.00 16.03 ? 899 VAL A CG1 1 ATOM 7057 C CG2 . VAL A 1 899 ? 28.305 53.098 -31.078 1.00 13.55 ? 899 VAL A CG2 1 ATOM 7058 N N . ASN A 1 900 ? 28.726 51.158 -34.359 1.00 15.49 ? 900 ASN A N 1 ATOM 7059 C CA . ASN A 1 900 ? 27.981 49.978 -34.811 1.00 17.00 ? 900 ASN A CA 1 ATOM 7060 C C . ASN A 1 900 ? 28.863 48.749 -35.049 1.00 16.91 ? 900 ASN A C 1 ATOM 7061 O O . ASN A 1 900 ? 28.380 47.625 -35.024 1.00 18.23 ? 900 ASN A O 1 ATOM 7062 C CB . ASN A 1 900 ? 27.189 50.308 -36.077 1.00 18.87 ? 900 ASN A CB 1 ATOM 7063 C CG . ASN A 1 900 ? 28.055 50.868 -37.143 1.00 20.34 ? 900 ASN A CG 1 ATOM 7064 O OD1 . ASN A 1 900 ? 28.659 51.926 -36.974 1.00 21.74 ? 900 ASN A OD1 1 ATOM 7065 N ND2 . ASN A 1 900 ? 28.156 50.153 -38.258 1.00 22.86 ? 900 ASN A ND2 1 ATOM 7066 N N . ASN A 1 901 ? 30.155 48.952 -35.262 1.00 16.16 ? 901 ASN A N 1 ATOM 7067 C CA . ASN A 1 901 ? 31.035 47.821 -35.497 1.00 16.97 ? 901 ASN A CA 1 ATOM 7068 C C . ASN A 1 901 ? 31.793 47.417 -34.255 1.00 16.97 ? 901 ASN A C 1 ATOM 7069 O O . ASN A 1 901 ? 32.545 46.445 -34.282 1.00 16.03 ? 901 ASN A O 1 ATOM 7070 C CB . ASN A 1 901 ? 32.048 48.149 -36.594 1.00 19.02 ? 901 ASN A CB 1 ATOM 7071 C CG . ASN A 1 901 ? 31.419 48.157 -37.966 1.00 22.17 ? 901 ASN A CG 1 ATOM 7072 O OD1 . ASN A 1 901 ? 30.548 47.332 -38.255 1.00 24.47 ? 901 ASN A OD1 1 ATOM 7073 N ND2 . ASN A 1 901 ? 31.864 49.081 -38.837 1.00 23.58 ? 901 ASN A ND2 1 ATOM 7074 N N . CYS A 1 902 ? 31.613 48.163 -33.169 1.00 15.07 ? 902 CYS A N 1 ATOM 7075 C CA . CYS A 1 902 ? 32.347 47.847 -31.961 1.00 15.32 ? 902 CYS A CA 1 ATOM 7076 C C . CYS A 1 902 ? 31.822 46.634 -31.203 1.00 14.98 ? 902 CYS A C 1 ATOM 7077 O O . CYS A 1 902 ? 30.617 46.426 -31.111 1.00 15.40 ? 902 CYS A O 1 ATOM 7078 C CB . CYS A 1 902 ? 32.336 49.040 -31.021 1.00 15.10 ? 902 CYS A CB 1 ATOM 7079 S SG . CYS A 1 902 ? 33.085 50.565 -31.667 1.00 14.32 ? 902 CYS A SG 1 ATOM 7080 N N . VAL A 1 903 ? 32.732 45.835 -30.662 1.00 13.80 ? 903 VAL A N 1 ATOM 7081 C CA . VAL A 1 903 ? 32.332 44.687 -29.854 1.00 14.25 ? 903 VAL A CA 1 ATOM 7082 C C . VAL A 1 903 ? 32.031 45.257 -28.465 1.00 14.94 ? 903 VAL A C 1 ATOM 7083 O O . VAL A 1 903 ? 32.934 45.678 -27.742 1.00 14.96 ? 903 VAL A O 1 ATOM 7084 C CB . VAL A 1 903 ? 33.452 43.633 -29.789 1.00 14.34 ? 903 VAL A CB 1 ATOM 7085 C CG1 . VAL A 1 903 ? 33.068 42.511 -28.802 1.00 12.50 ? 903 VAL A CG1 1 ATOM 7086 C CG2 . VAL A 1 903 ? 33.649 43.045 -31.188 1.00 13.25 ? 903 VAL A CG2 1 ATOM 7087 N N . ARG A 1 904 ? 30.758 45.312 -28.119 1.00 15.18 ? 904 ARG A N 1 ATOM 7088 C CA . ARG A 1 904 ? 30.336 45.866 -26.835 1.00 16.60 ? 904 ARG A CA 1 ATOM 7089 C C . ARG A 1 904 ? 29.797 44.841 -25.848 1.00 16.20 ? 904 ARG A C 1 ATOM 7090 O O . ARG A 1 904 ? 29.452 43.723 -26.223 1.00 14.68 ? 904 ARG A O 1 ATOM 7091 C CB . ARG A 1 904 ? 29.256 46.936 -27.059 1.00 16.68 ? 904 ARG A CB 1 ATOM 7092 C CG . ARG A 1 904 ? 29.805 48.221 -27.650 1.00 18.92 ? 904 ARG A CG 1 ATOM 7093 C CD . ARG A 1 904 ? 28.683 49.205 -27.956 1.00 20.71 ? 904 ARG A CD 1 ATOM 7094 N NE . ARG A 1 904 ? 27.986 48.857 -29.183 1.00 21.45 ? 904 ARG A NE 1 ATOM 7095 C CZ . ARG A 1 904 ? 27.021 49.603 -29.717 1.00 24.36 ? 904 ARG A CZ 1 ATOM 7096 N NH1 . ARG A 1 904 ? 26.647 50.726 -29.112 1.00 22.63 ? 904 ARG A NH1 1 ATOM 7097 N NH2 . ARG A 1 904 ? 26.443 49.239 -30.859 1.00 21.71 ? 904 ARG A NH2 1 ATOM 7098 N N . PRO A 1 905 ? 29.730 45.219 -24.556 1.00 16.00 ? 905 PRO A N 1 ATOM 7099 C CA . PRO A 1 905 ? 29.208 44.298 -23.542 1.00 14.61 ? 905 PRO A CA 1 ATOM 7100 C C . PRO A 1 905 ? 27.732 44.075 -23.870 1.00 15.25 ? 905 PRO A C 1 ATOM 7101 O O . PRO A 1 905 ? 27.112 44.911 -24.524 1.00 13.47 ? 905 PRO A O 1 ATOM 7102 C CB . PRO A 1 905 ? 29.355 45.076 -22.236 1.00 14.64 ? 905 PRO A CB 1 ATOM 7103 C CG . PRO A 1 905 ? 30.446 46.102 -22.529 1.00 15.03 ? 905 PRO A CG 1 ATOM 7104 C CD . PRO A 1 905 ? 30.232 46.476 -23.959 1.00 15.52 ? 905 PRO A CD 1 ATOM 7105 N N . SER A 1 906 ? 27.173 42.958 -23.424 1.00 16.09 ? 906 SER A N 1 ATOM 7106 C CA . SER A 1 906 ? 25.760 42.695 -23.663 1.00 18.17 ? 906 SER A CA 1 ATOM 7107 C C . SER A 1 906 ? 24.945 43.711 -22.863 1.00 18.46 ? 906 SER A C 1 ATOM 7108 O O . SER A 1 906 ? 25.472 44.432 -22.000 1.00 16.63 ? 906 SER A O 1 ATOM 7109 C CB . SER A 1 906 ? 25.373 41.289 -23.196 1.00 19.22 ? 906 SER A CB 1 ATOM 7110 O OG . SER A 1 906 ? 24.884 41.339 -21.852 1.00 23.97 ? 906 SER A OG 1 ATOM 7111 N N . LYS A 1 907 ? 23.648 43.738 -23.122 1.00 19.52 ? 907 LYS A N 1 ATOM 7112 C CA . LYS A 1 907 ? 22.759 44.668 -22.443 1.00 21.98 ? 907 LYS A CA 1 ATOM 7113 C C . LYS A 1 907 ? 22.691 44.554 -20.930 1.00 20.54 ? 907 LYS A C 1 ATOM 7114 O O . LYS A 1 907 ? 22.327 45.504 -20.276 1.00 22.06 ? 907 LYS A O 1 ATOM 7115 C CB . LYS A 1 907 ? 21.347 44.519 -22.994 1.00 24.94 ? 907 LYS A CB 1 ATOM 7116 C CG . LYS A 1 907 ? 21.253 44.781 -24.485 1.00 30.73 ? 907 LYS A CG 1 ATOM 7117 C CD . LYS A 1 907 ? 19.802 44.658 -24.951 1.00 34.29 ? 907 LYS A CD 1 ATOM 7118 C CE . LYS A 1 907 ? 19.657 44.967 -26.435 1.00 36.16 ? 907 LYS A CE 1 ATOM 7119 N NZ . LYS A 1 907 ? 18.232 44.729 -26.825 1.00 38.53 ? 907 LYS A NZ 1 ATOM 7120 N N . LEU A 1 908 ? 23.013 43.398 -20.365 1.00 20.07 ? 908 LEU A N 1 ATOM 7121 C CA . LEU A 1 908 ? 22.927 43.238 -18.915 1.00 19.40 ? 908 LEU A CA 1 ATOM 7122 C C . LEU A 1 908 ? 24.247 43.524 -18.188 1.00 17.45 ? 908 LEU A C 1 ATOM 7123 O O . LEU A 1 908 ? 24.315 43.486 -16.968 1.00 16.47 ? 908 LEU A O 1 ATOM 7124 C CB . LEU A 1 908 ? 22.445 41.818 -18.591 1.00 20.99 ? 908 LEU A CB 1 ATOM 7125 C CG . LEU A 1 908 ? 21.177 41.322 -19.311 1.00 22.11 ? 908 LEU A CG 1 ATOM 7126 C CD1 . LEU A 1 908 ? 20.920 39.834 -18.982 1.00 23.14 ? 908 LEU A CD1 1 ATOM 7127 C CD2 . LEU A 1 908 ? 19.976 42.166 -18.892 1.00 23.46 ? 908 LEU A CD2 1 ATOM 7128 N N . HIS A 1 909 ? 25.307 43.795 -18.940 1.00 16.45 ? 909 HIS A N 1 ATOM 7129 C CA . HIS A 1 909 ? 26.610 44.074 -18.324 1.00 15.71 ? 909 HIS A CA 1 ATOM 7130 C C . HIS A 1 909 ? 26.549 45.470 -17.672 1.00 15.43 ? 909 HIS A C 1 ATOM 7131 O O . HIS A 1 909 ? 26.075 46.414 -18.282 1.00 16.39 ? 909 HIS A O 1 ATOM 7132 C CB . HIS A 1 909 ? 27.695 44.020 -19.401 1.00 14.68 ? 909 HIS A CB 1 ATOM 7133 C CG . HIS A 1 909 ? 29.074 43.795 -18.861 1.00 13.44 ? 909 HIS A CG 1 ATOM 7134 N ND1 . HIS A 1 909 ? 29.763 44.757 -18.146 1.00 14.02 ? 909 HIS A ND1 1 ATOM 7135 C CD2 . HIS A 1 909 ? 29.901 42.726 -18.951 1.00 12.13 ? 909 HIS A CD2 1 ATOM 7136 C CE1 . HIS A 1 909 ? 30.960 44.290 -17.830 1.00 14.10 ? 909 HIS A CE1 1 ATOM 7137 N NE2 . HIS A 1 909 ? 31.068 43.059 -18.310 1.00 12.70 ? 909 HIS A NE2 1 ATOM 7138 N N . PRO A 1 910 ? 27.020 45.605 -16.424 1.00 14.81 ? 910 PRO A N 1 ATOM 7139 C CA . PRO A 1 910 ? 26.992 46.908 -15.730 1.00 13.54 ? 910 PRO A CA 1 ATOM 7140 C C . PRO A 1 910 ? 28.070 47.917 -16.138 1.00 12.75 ? 910 PRO A C 1 ATOM 7141 O O . PRO A 1 910 ? 28.069 49.045 -15.644 1.00 12.13 ? 910 PRO A O 1 ATOM 7142 C CB . PRO A 1 910 ? 27.148 46.540 -14.249 1.00 14.40 ? 910 PRO A CB 1 ATOM 7143 C CG . PRO A 1 910 ? 27.086 45.028 -14.188 1.00 15.33 ? 910 PRO A CG 1 ATOM 7144 C CD . PRO A 1 910 ? 27.558 44.555 -15.539 1.00 15.02 ? 910 PRO A CD 1 ATOM 7145 N N . ALA A 1 911 ? 29.001 47.512 -17.004 1.00 11.78 ? 911 ALA A N 1 ATOM 7146 C CA . ALA A 1 911 ? 30.074 48.399 -17.420 1.00 10.89 ? 911 ALA A CA 1 ATOM 7147 C C . ALA A 1 911 ? 30.026 48.867 -18.862 1.00 10.64 ? 911 ALA A C 1 ATOM 7148 O O . ALA A 1 911 ? 29.314 48.305 -19.705 1.00 9.65 ? 911 ALA A O 1 ATOM 7149 C CB . ALA A 1 911 ? 31.421 47.718 -17.200 1.00 10.57 ? 911 ALA A CB 1 ATOM 7150 N N . GLY A 1 912 ? 30.862 49.873 -19.133 1.00 10.17 ? 912 GLY A N 1 ATOM 7151 C CA . GLY A 1 912 ? 31.008 50.415 -20.468 1.00 9.81 ? 912 GLY A CA 1 ATOM 7152 C C . GLY A 1 912 ? 32.485 50.667 -20.678 1.00 10.11 ? 912 GLY A C 1 ATOM 7153 O O . GLY A 1 912 ? 33.237 50.789 -19.684 1.00 10.04 ? 912 GLY A O 1 ATOM 7154 N N . TYR A 1 913 ? 32.913 50.753 -21.936 1.00 10.54 ? 913 TYR A N 1 ATOM 7155 C CA . TYR A 1 913 ? 34.326 50.997 -22.248 1.00 10.23 ? 913 TYR A CA 1 ATOM 7156 C C . TYR A 1 913 ? 34.525 52.034 -23.345 1.00 10.83 ? 913 TYR A C 1 ATOM 7157 O O . TYR A 1 913 ? 33.744 52.132 -24.286 1.00 9.87 ? 913 TYR A O 1 ATOM 7158 C CB . TYR A 1 913 ? 35.032 49.708 -22.665 1.00 12.18 ? 913 TYR A CB 1 ATOM 7159 C CG . TYR A 1 913 ? 35.021 48.670 -21.581 1.00 11.08 ? 913 TYR A CG 1 ATOM 7160 C CD1 . TYR A 1 913 ? 34.031 47.706 -21.537 1.00 12.38 ? 913 TYR A CD1 1 ATOM 7161 C CD2 . TYR A 1 913 ? 35.932 48.733 -20.528 1.00 10.67 ? 913 TYR A CD2 1 ATOM 7162 C CE1 . TYR A 1 913 ? 33.936 46.819 -20.452 1.00 11.62 ? 913 TYR A CE1 1 ATOM 7163 C CE2 . TYR A 1 913 ? 35.856 47.858 -19.447 1.00 10.50 ? 913 TYR A CE2 1 ATOM 7164 C CZ . TYR A 1 913 ? 34.852 46.904 -19.413 1.00 11.22 ? 913 TYR A CZ 1 ATOM 7165 O OH . TYR A 1 913 ? 34.740 46.054 -18.333 1.00 12.20 ? 913 TYR A OH 1 ATOM 7166 N N . LEU A 1 914 ? 35.584 52.808 -23.213 1.00 10.58 ? 914 LEU A N 1 ATOM 7167 C CA . LEU A 1 914 ? 35.914 53.821 -24.200 1.00 10.85 ? 914 LEU A CA 1 ATOM 7168 C C . LEU A 1 914 ? 36.543 53.215 -25.445 1.00 10.68 ? 914 LEU A C 1 ATOM 7169 O O . LEU A 1 914 ? 37.016 52.059 -25.453 1.00 10.34 ? 914 LEU A O 1 ATOM 7170 C CB . LEU A 1 914 ? 36.919 54.814 -23.619 1.00 8.69 ? 914 LEU A CB 1 ATOM 7171 C CG . LEU A 1 914 ? 36.481 55.660 -22.421 1.00 9.55 ? 914 LEU A CG 1 ATOM 7172 C CD1 . LEU A 1 914 ? 37.599 56.662 -22.108 1.00 4.33 ? 914 LEU A CD1 1 ATOM 7173 C CD2 . LEU A 1 914 ? 35.130 56.404 -22.708 1.00 8.94 ? 914 LEU A CD2 1 ATOM 7174 N N . THR A 1 915 ? 36.554 54.026 -26.498 1.00 11.17 ? 915 THR A N 1 ATOM 7175 C CA . THR A 1 915 ? 37.183 53.672 -27.747 1.00 10.56 ? 915 THR A CA 1 ATOM 7176 C C . THR A 1 915 ? 38.580 54.265 -27.612 1.00 11.26 ? 915 THR A C 1 ATOM 7177 O O . THR A 1 915 ? 38.864 55.081 -26.718 1.00 9.61 ? 915 THR A O 1 ATOM 7178 C CB . THR A 1 915 ? 36.573 54.406 -28.932 1.00 12.32 ? 915 THR A CB 1 ATOM 7179 O OG1 . THR A 1 915 ? 36.546 55.821 -28.639 1.00 13.22 ? 915 THR A OG1 1 ATOM 7180 C CG2 . THR A 1 915 ? 35.185 53.892 -29.243 1.00 12.00 ? 915 THR A CG2 1 ATOM 7181 N N . SER A 1 916 ? 39.441 53.871 -28.532 1.00 11.39 ? 916 SER A N 1 ATOM 7182 C CA . SER A 1 916 ? 40.811 54.364 -28.583 1.00 11.86 ? 916 SER A CA 1 ATOM 7183 C C . SER A 1 916 ? 40.823 55.896 -28.685 1.00 12.08 ? 916 SER A C 1 ATOM 7184 O O . SER A 1 916 ? 41.550 56.557 -27.957 1.00 11.70 ? 916 SER A O 1 ATOM 7185 C CB . SER A 1 916 ? 41.516 53.758 -29.795 1.00 12.71 ? 916 SER A CB 1 ATOM 7186 O OG . SER A 1 916 ? 42.759 54.406 -30.025 1.00 17.18 ? 916 SER A OG 1 ATOM 7187 N N . ALA A 1 917 ? 40.002 56.469 -29.568 1.00 11.56 ? 917 ALA A N 1 ATOM 7188 C CA . ALA A 1 917 ? 39.999 57.931 -29.712 1.00 10.26 ? 917 ALA A CA 1 ATOM 7189 C C . ALA A 1 917 ? 39.562 58.633 -28.436 1.00 9.80 ? 917 ALA A C 1 ATOM 7190 O O . ALA A 1 917 ? 40.159 59.644 -28.053 1.00 9.57 ? 917 ALA A O 1 ATOM 7191 C CB . ALA A 1 917 ? 39.084 58.368 -30.885 1.00 11.51 ? 917 ALA A CB 1 ATOM 7192 N N . ALA A 1 918 ? 38.525 58.108 -27.781 1.00 8.47 ? 918 ALA A N 1 ATOM 7193 C CA . ALA A 1 918 ? 38.024 58.736 -26.551 1.00 9.07 ? 918 ALA A CA 1 ATOM 7194 C C . ALA A 1 918 ? 39.064 58.636 -25.443 1.00 8.97 ? 918 ALA A C 1 ATOM 7195 O O . ALA A 1 918 ? 39.273 59.581 -24.678 1.00 8.65 ? 918 ALA A O 1 ATOM 7196 C CB . ALA A 1 918 ? 36.704 58.109 -26.119 1.00 7.40 ? 918 ALA A CB 1 ATOM 7197 N N . HIS A 1 919 ? 39.746 57.509 -25.388 1.00 7.69 ? 919 HIS A N 1 ATOM 7198 C CA . HIS A 1 919 ? 40.765 57.319 -24.372 1.00 9.17 ? 919 HIS A CA 1 ATOM 7199 C C . HIS A 1 919 ? 41.937 58.279 -24.599 1.00 8.84 ? 919 HIS A C 1 ATOM 7200 O O . HIS A 1 919 ? 42.369 58.955 -23.676 1.00 9.13 ? 919 HIS A O 1 ATOM 7201 C CB . HIS A 1 919 ? 41.241 55.870 -24.377 1.00 8.81 ? 919 HIS A CB 1 ATOM 7202 C CG . HIS A 1 919 ? 42.375 55.618 -23.436 1.00 11.84 ? 919 HIS A CG 1 ATOM 7203 N ND1 . HIS A 1 919 ? 43.628 55.227 -23.864 1.00 12.07 ? 919 HIS A ND1 1 ATOM 7204 C CD2 . HIS A 1 919 ? 42.441 55.682 -22.088 1.00 10.15 ? 919 HIS A CD2 1 ATOM 7205 C CE1 . HIS A 1 919 ? 44.417 55.048 -22.822 1.00 10.60 ? 919 HIS A CE1 1 ATOM 7206 N NE2 . HIS A 1 919 ? 43.722 55.318 -21.736 1.00 12.11 ? 919 HIS A NE2 1 ATOM 7207 N N . LYS A 1 920 ? 42.458 58.343 -25.817 1.00 9.04 ? 920 LYS A N 1 ATOM 7208 C CA . LYS A 1 920 ? 43.545 59.270 -26.054 1.00 8.71 ? 920 LYS A CA 1 ATOM 7209 C C . LYS A 1 920 ? 43.099 60.713 -25.783 1.00 8.47 ? 920 LYS A C 1 ATOM 7210 O O . LYS A 1 920 ? 43.899 61.533 -25.325 1.00 7.74 ? 920 LYS A O 1 ATOM 7211 C CB . LYS A 1 920 ? 44.073 59.122 -27.487 1.00 10.81 ? 920 LYS A CB 1 ATOM 7212 C CG . LYS A 1 920 ? 44.932 57.852 -27.660 1.00 13.48 ? 920 LYS A CG 1 ATOM 7213 C CD . LYS A 1 920 ? 45.612 57.795 -29.023 1.00 13.63 ? 920 LYS A CD 1 ATOM 7214 C CE . LYS A 1 920 ? 46.566 56.624 -29.073 1.00 13.51 ? 920 LYS A CE 1 ATOM 7215 N NZ . LYS A 1 920 ? 47.725 56.813 -28.175 1.00 15.09 ? 920 LYS A NZ 1 ATOM 7216 N N . ALA A 1 921 ? 41.839 61.033 -26.071 1.00 8.50 ? 921 ALA A N 1 ATOM 7217 C CA . ALA A 1 921 ? 41.360 62.403 -25.824 1.00 9.26 ? 921 ALA A CA 1 ATOM 7218 C C . ALA A 1 921 ? 41.405 62.663 -24.311 1.00 9.81 ? 921 ALA A C 1 ATOM 7219 O O . ALA A 1 921 ? 41.741 63.774 -23.872 1.00 9.93 ? 921 ALA A O 1 ATOM 7220 C CB . ALA A 1 921 ? 39.932 62.591 -26.358 1.00 6.62 ? 921 ALA A CB 1 ATOM 7221 N N . SER A 1 922 ? 41.054 61.662 -23.503 1.00 9.39 ? 922 SER A N 1 ATOM 7222 C CA . SER A 1 922 ? 41.114 61.860 -22.044 1.00 9.31 ? 922 SER A CA 1 ATOM 7223 C C . SER A 1 922 ? 42.569 62.091 -21.632 1.00 9.10 ? 922 SER A C 1 ATOM 7224 O O . SER A 1 922 ? 42.873 62.954 -20.804 1.00 9.33 ? 922 SER A O 1 ATOM 7225 C CB . SER A 1 922 ? 40.584 60.626 -21.282 1.00 9.94 ? 922 SER A CB 1 ATOM 7226 O OG . SER A 1 922 ? 40.580 60.899 -19.880 1.00 5.80 ? 922 SER A OG 1 ATOM 7227 N N . GLN A 1 923 ? 43.482 61.308 -22.201 1.00 8.78 ? 923 GLN A N 1 ATOM 7228 C CA . GLN A 1 923 ? 44.889 61.476 -21.867 1.00 8.73 ? 923 GLN A CA 1 ATOM 7229 C C . GLN A 1 923 ? 45.425 62.855 -22.282 1.00 8.59 ? 923 GLN A C 1 ATOM 7230 O O . GLN A 1 923 ? 46.287 63.396 -21.596 1.00 8.78 ? 923 GLN A O 1 ATOM 7231 C CB . GLN A 1 923 ? 45.721 60.372 -22.511 1.00 7.89 ? 923 GLN A CB 1 ATOM 7232 C CG . GLN A 1 923 ? 45.442 58.973 -21.935 1.00 7.22 ? 923 GLN A CG 1 ATOM 7233 C CD . GLN A 1 923 ? 46.378 57.971 -22.531 1.00 9.15 ? 923 GLN A CD 1 ATOM 7234 O OE1 . GLN A 1 923 ? 46.505 57.910 -23.767 1.00 8.68 ? 923 GLN A OE1 1 ATOM 7235 N NE2 . GLN A 1 923 ? 47.054 57.171 -21.677 1.00 6.82 ? 923 GLN A NE2 1 ATOM 7236 N N . SER A 1 924 ? 44.899 63.433 -23.368 1.00 8.14 ? 924 SER A N 1 ATOM 7237 C CA . SER A 1 924 ? 45.355 64.764 -23.827 1.00 9.77 ? 924 SER A CA 1 ATOM 7238 C C . SER A 1 924 ? 44.948 65.837 -22.815 1.00 10.17 ? 924 SER A C 1 ATOM 7239 O O . SER A 1 924 ? 45.590 66.878 -22.707 1.00 11.74 ? 924 SER A O 1 ATOM 7240 C CB . SER A 1 924 ? 44.754 65.137 -25.204 1.00 10.72 ? 924 SER A CB 1 ATOM 7241 O OG . SER A 1 924 ? 43.372 65.511 -25.069 1.00 10.11 ? 924 SER A OG 1 ATOM 7242 N N . LEU A 1 925 ? 43.861 65.596 -22.093 1.00 9.02 ? 925 LEU A N 1 ATOM 7243 C CA . LEU A 1 925 ? 43.397 66.544 -21.070 1.00 9.69 ? 925 LEU A CA 1 ATOM 7244 C C . LEU A 1 925 ? 44.126 66.380 -19.722 1.00 9.26 ? 925 LEU A C 1 ATOM 7245 O O . LEU A 1 925 ? 44.531 67.373 -19.078 1.00 9.17 ? 925 LEU A O 1 ATOM 7246 C CB . LEU A 1 925 ? 41.873 66.350 -20.815 1.00 9.49 ? 925 LEU A CB 1 ATOM 7247 C CG . LEU A 1 925 ? 40.945 66.606 -22.028 1.00 11.38 ? 925 LEU A CG 1 ATOM 7248 C CD1 . LEU A 1 925 ? 39.491 66.173 -21.689 1.00 9.83 ? 925 LEU A CD1 1 ATOM 7249 C CD2 . LEU A 1 925 ? 41.005 68.089 -22.412 1.00 9.07 ? 925 LEU A CD2 1 ATOM 7250 N N . LEU A 1 926 ? 44.252 65.133 -19.274 1.00 6.75 ? 926 LEU A N 1 ATOM 7251 C CA . LEU A 1 926 ? 44.847 64.870 -17.969 1.00 8.60 ? 926 LEU A CA 1 ATOM 7252 C C . LEU A 1 926 ? 46.359 64.836 -17.960 1.00 8.87 ? 926 LEU A C 1 ATOM 7253 O O . LEU A 1 926 ? 46.963 65.244 -16.986 1.00 9.75 ? 926 LEU A O 1 ATOM 7254 C CB . LEU A 1 926 ? 44.324 63.548 -17.406 1.00 6.99 ? 926 LEU A CB 1 ATOM 7255 C CG . LEU A 1 926 ? 42.821 63.534 -17.121 1.00 8.97 ? 926 LEU A CG 1 ATOM 7256 C CD1 . LEU A 1 926 ? 42.434 62.166 -16.554 1.00 8.33 ? 926 LEU A CD1 1 ATOM 7257 C CD2 . LEU A 1 926 ? 42.483 64.673 -16.133 1.00 10.03 ? 926 LEU A CD2 1 ATOM 7258 N N . ASP A 1 927 ? 46.965 64.335 -19.029 1.00 6.80 ? 927 ASP A N 1 ATOM 7259 C CA . ASP A 1 927 ? 48.417 64.258 -19.061 1.00 8.10 ? 927 ASP A CA 1 ATOM 7260 C C . ASP A 1 927 ? 49.021 64.771 -20.369 1.00 7.24 ? 927 ASP A C 1 ATOM 7261 O O . ASP A 1 927 ? 49.610 64.023 -21.143 1.00 7.14 ? 927 ASP A O 1 ATOM 7262 C CB . ASP A 1 927 ? 48.854 62.815 -18.741 1.00 7.01 ? 927 ASP A CB 1 ATOM 7263 C CG . ASP A 1 927 ? 48.517 62.417 -17.297 1.00 9.51 ? 927 ASP A CG 1 ATOM 7264 O OD1 . ASP A 1 927 ? 49.266 62.785 -16.347 1.00 8.48 ? 927 ASP A OD1 1 ATOM 7265 O OD2 . ASP A 1 927 ? 47.474 61.741 -17.118 1.00 7.49 ? 927 ASP A OD2 1 ATOM 7266 N N . PRO A 1 928 ? 48.872 66.084 -20.619 1.00 8.55 ? 928 PRO A N 1 ATOM 7267 C CA . PRO A 1 928 ? 49.386 66.751 -21.819 1.00 8.37 ? 928 PRO A CA 1 ATOM 7268 C C . PRO A 1 928 ? 50.904 66.781 -21.783 1.00 8.75 ? 928 PRO A C 1 ATOM 7269 O O . PRO A 1 928 ? 51.516 66.472 -20.755 1.00 8.46 ? 928 PRO A O 1 ATOM 7270 C CB . PRO A 1 928 ? 48.819 68.173 -21.701 1.00 8.44 ? 928 PRO A CB 1 ATOM 7271 C CG . PRO A 1 928 ? 48.916 68.412 -20.234 1.00 10.16 ? 928 PRO A CG 1 ATOM 7272 C CD . PRO A 1 928 ? 48.390 67.076 -19.642 1.00 8.60 ? 928 PRO A CD 1 ATOM 7273 N N . LEU A 1 929 ? 51.514 67.156 -22.909 1.00 8.94 ? 929 LEU A N 1 ATOM 7274 C CA . LEU A 1 929 ? 52.968 67.309 -22.951 1.00 9.68 ? 929 LEU A CA 1 ATOM 7275 C C . LEU A 1 929 ? 53.281 68.452 -21.988 1.00 9.31 ? 929 LEU A C 1 ATOM 7276 O O . LEU A 1 929 ? 52.479 69.354 -21.819 1.00 9.70 ? 929 LEU A O 1 ATOM 7277 C CB . LEU A 1 929 ? 53.449 67.728 -24.350 1.00 9.42 ? 929 LEU A CB 1 ATOM 7278 C CG . LEU A 1 929 ? 53.179 66.743 -25.492 1.00 10.87 ? 929 LEU A CG 1 ATOM 7279 C CD1 . LEU A 1 929 ? 53.677 67.360 -26.809 1.00 10.10 ? 929 LEU A CD1 1 ATOM 7280 C CD2 . LEU A 1 929 ? 53.929 65.415 -25.216 1.00 9.79 ? 929 LEU A CD2 1 ATOM 7281 N N . ASP A 1 930 ? 54.435 68.405 -21.335 1.00 10.90 ? 930 ASP A N 1 ATOM 7282 C CA . ASP A 1 930 ? 54.841 69.506 -20.462 1.00 10.92 ? 930 ASP A CA 1 ATOM 7283 C C . ASP A 1 930 ? 55.761 70.371 -21.324 1.00 10.79 ? 930 ASP A C 1 ATOM 7284 O O . ASP A 1 930 ? 56.544 69.851 -22.152 1.00 11.51 ? 930 ASP A O 1 ATOM 7285 C CB . ASP A 1 930 ? 55.590 68.962 -19.241 1.00 9.87 ? 930 ASP A CB 1 ATOM 7286 C CG . ASP A 1 930 ? 54.766 67.929 -18.498 1.00 14.26 ? 930 ASP A CG 1 ATOM 7287 O OD1 . ASP A 1 930 ? 53.708 68.327 -17.921 1.00 10.38 ? 930 ASP A OD1 1 ATOM 7288 O OD2 . ASP A 1 930 ? 55.169 66.727 -18.528 1.00 11.19 ? 930 ASP A OD2 1 ATOM 7289 N N . LYS A 1 931 ? 55.685 71.680 -21.141 1.00 10.71 ? 931 LYS A N 1 ATOM 7290 C CA . LYS A 1 931 ? 56.493 72.580 -21.948 1.00 10.62 ? 931 LYS A CA 1 ATOM 7291 C C . LYS A 1 931 ? 57.444 73.393 -21.100 1.00 10.96 ? 931 LYS A C 1 ATOM 7292 O O . LYS A 1 931 ? 57.036 73.974 -20.078 1.00 9.87 ? 931 LYS A O 1 ATOM 7293 C CB . LYS A 1 931 ? 55.577 73.536 -22.745 1.00 11.73 ? 931 LYS A CB 1 ATOM 7294 C CG . LYS A 1 931 ? 54.525 72.852 -23.666 1.00 11.02 ? 931 LYS A CG 1 ATOM 7295 C CD . LYS A 1 931 ? 53.670 73.888 -24.432 1.00 12.70 ? 931 LYS A CD 1 ATOM 7296 C CE . LYS A 1 931 ? 52.936 74.792 -23.465 1.00 15.28 ? 931 LYS A CE 1 ATOM 7297 N NZ . LYS A 1 931 ? 51.914 75.638 -24.071 1.00 16.36 ? 931 LYS A NZ 1 ATOM 7298 N N . PHE A 1 932 ? 58.710 73.455 -21.529 1.00 10.19 ? 932 PHE A N 1 ATOM 7299 C CA . PHE A 1 932 ? 59.728 74.212 -20.799 1.00 9.47 ? 932 PHE A CA 1 ATOM 7300 C C . PHE A 1 932 ? 60.455 75.226 -21.690 1.00 9.46 ? 932 PHE A C 1 ATOM 7301 O O . PHE A 1 932 ? 60.888 74.893 -22.777 1.00 9.05 ? 932 PHE A O 1 ATOM 7302 C CB . PHE A 1 932 ? 60.805 73.297 -20.224 1.00 9.24 ? 932 PHE A CB 1 ATOM 7303 C CG . PHE A 1 932 ? 60.288 72.195 -19.385 1.00 8.45 ? 932 PHE A CG 1 ATOM 7304 C CD1 . PHE A 1 932 ? 59.715 71.060 -19.972 1.00 9.41 ? 932 PHE A CD1 1 ATOM 7305 C CD2 . PHE A 1 932 ? 60.422 72.262 -18.001 1.00 9.43 ? 932 PHE A CD2 1 ATOM 7306 C CE1 . PHE A 1 932 ? 59.274 69.974 -19.188 1.00 9.07 ? 932 PHE A CE1 1 ATOM 7307 C CE2 . PHE A 1 932 ? 59.999 71.200 -17.205 1.00 10.87 ? 932 PHE A CE2 1 ATOM 7308 C CZ . PHE A 1 932 ? 59.419 70.041 -17.818 1.00 11.32 ? 932 PHE A CZ 1 ATOM 7309 N N . ILE A 1 933 ? 60.605 76.447 -21.204 1.00 9.57 ? 933 ILE A N 1 ATOM 7310 C CA . ILE A 1 933 ? 61.297 77.503 -21.954 1.00 10.12 ? 933 ILE A CA 1 ATOM 7311 C C . ILE A 1 933 ? 62.642 77.718 -21.276 1.00 11.66 ? 933 ILE A C 1 ATOM 7312 O O . ILE A 1 933 ? 62.689 77.965 -20.067 1.00 11.02 ? 933 ILE A O 1 ATOM 7313 C CB . ILE A 1 933 ? 60.539 78.837 -21.864 1.00 9.96 ? 933 ILE A CB 1 ATOM 7314 C CG1 . ILE A 1 933 ? 59.071 78.644 -22.294 1.00 9.47 ? 933 ILE A CG1 1 ATOM 7315 C CG2 . ILE A 1 933 ? 61.251 79.887 -22.682 1.00 7.19 ? 933 ILE A CG2 1 ATOM 7316 C CD1 . ILE A 1 933 ? 58.239 79.929 -22.134 1.00 8.58 ? 933 ILE A CD1 1 ATOM 7317 N N . PHE A 1 934 ? 63.730 77.614 -22.041 1.00 11.29 ? 934 PHE A N 1 ATOM 7318 C CA . PHE A 1 934 ? 65.047 77.818 -21.468 1.00 12.76 ? 934 PHE A CA 1 ATOM 7319 C C . PHE A 1 934 ? 65.172 79.302 -21.005 1.00 13.83 ? 934 PHE A C 1 ATOM 7320 O O . PHE A 1 934 ? 64.853 80.241 -21.744 1.00 13.12 ? 934 PHE A O 1 ATOM 7321 C CB . PHE A 1 934 ? 66.129 77.459 -22.481 1.00 14.20 ? 934 PHE A CB 1 ATOM 7322 C CG . PHE A 1 934 ? 67.495 77.475 -21.887 1.00 15.64 ? 934 PHE A CG 1 ATOM 7323 C CD1 . PHE A 1 934 ? 67.895 76.458 -21.024 1.00 15.38 ? 934 PHE A CD1 1 ATOM 7324 C CD2 . PHE A 1 934 ? 68.345 78.565 -22.112 1.00 15.55 ? 934 PHE A CD2 1 ATOM 7325 C CE1 . PHE A 1 934 ? 69.142 76.519 -20.372 1.00 17.76 ? 934 PHE A CE1 1 ATOM 7326 C CE2 . PHE A 1 934 ? 69.593 78.655 -21.486 1.00 15.87 ? 934 PHE A CE2 1 ATOM 7327 C CZ . PHE A 1 934 ? 69.997 77.624 -20.605 1.00 17.35 ? 934 PHE A CZ 1 ATOM 7328 N N . ALA A 1 935 ? 65.641 79.514 -19.782 1.00 15.85 ? 935 ALA A N 1 ATOM 7329 C CA . ALA A 1 935 ? 65.666 80.869 -19.245 1.00 18.30 ? 935 ALA A CA 1 ATOM 7330 C C . ALA A 1 935 ? 66.817 81.805 -19.617 1.00 20.03 ? 935 ALA A C 1 ATOM 7331 O O . ALA A 1 935 ? 66.588 83.006 -19.754 1.00 22.67 ? 935 ALA A O 1 ATOM 7332 C CB . ALA A 1 935 ? 65.535 80.813 -17.742 1.00 18.82 ? 935 ALA A CB 1 ATOM 7333 N N . GLU A 1 936 ? 68.033 81.284 -19.764 1.00 18.58 ? 936 GLU A N 1 ATOM 7334 C CA . GLU A 1 936 ? 69.200 82.120 -20.099 1.00 19.87 ? 936 GLU A CA 1 ATOM 7335 C C . GLU A 1 936 ? 69.261 82.318 -21.628 1.00 19.15 ? 936 GLU A C 1 ATOM 7336 O O . GLU A 1 936 ? 68.483 81.704 -22.376 1.00 17.52 ? 936 GLU A O 1 ATOM 7337 C CB . GLU A 1 936 ? 70.494 81.429 -19.642 1.00 22.18 ? 936 GLU A CB 1 ATOM 7338 C CG . GLU A 1 936 ? 70.608 81.173 -18.116 1.00 25.90 ? 936 GLU A CG 1 ATOM 7339 C CD . GLU A 1 936 ? 71.674 80.095 -17.762 1.00 28.84 ? 936 GLU A CD 1 ATOM 7340 O OE1 . GLU A 1 936 ? 71.395 78.873 -17.938 1.00 29.65 ? 936 GLU A OE1 1 ATOM 7341 O OE2 . GLU A 1 936 ? 72.799 80.462 -17.318 1.00 29.87 ? 936 GLU A OE2 1 ATOM 7342 N N . ASN A 1 937 ? 70.194 83.140 -22.102 1.00 18.20 ? 937 ASN A N 1 ATOM 7343 C CA . ASN A 1 937 ? 70.262 83.347 -23.538 1.00 19.62 ? 937 ASN A CA 1 ATOM 7344 C C . ASN A 1 937 ? 70.828 82.171 -24.273 1.00 19.35 ? 937 ASN A C 1 ATOM 7345 O O . ASN A 1 937 ? 70.420 81.899 -25.412 1.00 20.25 ? 937 ASN A O 1 ATOM 7346 C CB . ASN A 1 937 ? 71.073 84.585 -23.877 1.00 19.87 ? 937 ASN A CB 1 ATOM 7347 C CG . ASN A 1 937 ? 70.450 85.829 -23.308 1.00 21.16 ? 937 ASN A CG 1 ATOM 7348 O OD1 . ASN A 1 937 ? 69.233 85.908 -23.136 1.00 21.42 ? 937 ASN A OD1 1 ATOM 7349 N ND2 . ASN A 1 937 ? 71.266 86.801 -23.018 1.00 22.22 ? 937 ASN A ND2 1 ATOM 7350 N N . GLU A 1 938 ? 71.766 81.469 -23.651 1.00 18.95 ? 938 GLU A N 1 ATOM 7351 C CA . GLU A 1 938 ? 72.357 80.331 -24.336 1.00 21.15 ? 938 GLU A CA 1 ATOM 7352 C C . GLU A 1 938 ? 72.419 79.067 -23.488 1.00 20.40 ? 938 GLU A C 1 ATOM 7353 O O . GLU A 1 938 ? 72.797 79.095 -22.307 1.00 19.50 ? 938 GLU A O 1 ATOM 7354 C CB . GLU A 1 938 ? 73.757 80.680 -24.848 1.00 24.82 ? 938 GLU A CB 1 ATOM 7355 C CG . GLU A 1 938 ? 74.485 79.462 -25.384 1.00 30.93 ? 938 GLU A CG 1 ATOM 7356 C CD . GLU A 1 938 ? 75.742 79.790 -26.176 1.00 35.18 ? 938 GLU A CD 1 ATOM 7357 O OE1 . GLU A 1 938 ? 76.548 80.638 -25.711 1.00 37.54 ? 938 GLU A OE1 1 ATOM 7358 O OE2 . GLU A 1 938 ? 75.923 79.175 -27.259 1.00 38.05 ? 938 GLU A OE2 1 ATOM 7359 N N . TRP A 1 939 ? 72.059 77.953 -24.112 1.00 19.40 ? 939 TRP A N 1 ATOM 7360 C CA . TRP A 1 939 ? 72.059 76.668 -23.431 1.00 19.57 ? 939 TRP A CA 1 ATOM 7361 C C . TRP A 1 939 ? 73.242 75.868 -23.948 1.00 20.00 ? 939 TRP A C 1 ATOM 7362 O O . TRP A 1 939 ? 73.126 75.196 -24.964 1.00 21.31 ? 939 TRP A O 1 ATOM 7363 C CB . TRP A 1 939 ? 70.751 75.914 -23.718 1.00 17.43 ? 939 TRP A CB 1 ATOM 7364 C CG . TRP A 1 939 ? 70.666 74.542 -23.047 1.00 15.85 ? 939 TRP A CG 1 ATOM 7365 C CD1 . TRP A 1 939 ? 71.587 73.977 -22.201 1.00 14.90 ? 939 TRP A CD1 1 ATOM 7366 C CD2 . TRP A 1 939 ? 69.598 73.586 -23.175 1.00 14.25 ? 939 TRP A CD2 1 ATOM 7367 N NE1 . TRP A 1 939 ? 71.155 72.726 -21.793 1.00 14.03 ? 939 TRP A NE1 1 ATOM 7368 C CE2 . TRP A 1 939 ? 69.939 72.465 -22.377 1.00 14.08 ? 939 TRP A CE2 1 ATOM 7369 C CE3 . TRP A 1 939 ? 68.387 73.568 -23.886 1.00 12.40 ? 939 TRP A CE3 1 ATOM 7370 C CZ2 . TRP A 1 939 ? 69.108 71.337 -22.270 1.00 13.33 ? 939 TRP A CZ2 1 ATOM 7371 C CZ3 . TRP A 1 939 ? 67.556 72.441 -23.774 1.00 13.24 ? 939 TRP A CZ3 1 ATOM 7372 C CH2 . TRP A 1 939 ? 67.927 71.344 -22.970 1.00 12.41 ? 939 TRP A CH2 1 ATOM 7373 N N . ILE A 1 940 ? 74.367 75.932 -23.240 1.00 20.18 ? 940 ILE A N 1 ATOM 7374 C CA . ILE A 1 940 ? 75.587 75.218 -23.640 1.00 20.77 ? 940 ILE A CA 1 ATOM 7375 C C . ILE A 1 940 ? 75.518 73.709 -23.349 1.00 19.99 ? 940 ILE A C 1 ATOM 7376 O O . ILE A 1 940 ? 75.250 73.312 -22.230 1.00 20.71 ? 940 ILE A O 1 ATOM 7377 C CB . ILE A 1 940 ? 76.807 75.817 -22.896 1.00 22.32 ? 940 ILE A CB 1 ATOM 7378 C CG1 . ILE A 1 940 ? 76.944 77.295 -23.260 1.00 24.09 ? 940 ILE A CG1 1 ATOM 7379 C CG2 . ILE A 1 940 ? 78.077 75.086 -23.284 1.00 22.82 ? 940 ILE A CG2 1 ATOM 7380 C CD1 . ILE A 1 940 ? 77.523 78.154 -22.168 1.00 27.36 ? 940 ILE A CD1 1 ATOM 7381 N N . GLY A 1 941 ? 75.762 72.881 -24.354 1.00 19.98 ? 941 GLY A N 1 ATOM 7382 C CA . GLY A 1 941 ? 75.740 71.442 -24.145 1.00 20.41 ? 941 GLY A CA 1 ATOM 7383 C C . GLY A 1 941 ? 74.380 70.804 -24.410 1.00 20.44 ? 941 GLY A C 1 ATOM 7384 O O . GLY A 1 941 ? 74.229 69.588 -24.259 1.00 20.07 ? 941 GLY A O 1 ATOM 7385 N N . ALA A 1 942 ? 73.410 71.626 -24.819 1.00 19.58 ? 942 ALA A N 1 ATOM 7386 C CA . ALA A 1 942 ? 72.049 71.176 -25.117 1.00 19.73 ? 942 ALA A CA 1 ATOM 7387 C C . ALA A 1 942 ? 71.991 69.974 -26.046 1.00 19.61 ? 942 ALA A C 1 ATOM 7388 O O . ALA A 1 942 ? 72.735 69.894 -27.010 1.00 20.75 ? 942 ALA A O 1 ATOM 7389 C CB . ALA A 1 942 ? 71.232 72.339 -25.720 1.00 18.32 ? 942 ALA A CB 1 ATOM 7390 N N . GLN A 1 943 ? 71.093 69.043 -25.759 1.00 18.97 ? 943 GLN A N 1 ATOM 7391 C CA . GLN A 1 943 ? 70.913 67.856 -26.576 1.00 18.08 ? 943 GLN A CA 1 ATOM 7392 C C . GLN A 1 943 ? 69.491 67.886 -27.085 1.00 17.54 ? 943 GLN A C 1 ATOM 7393 O O . GLN A 1 943 ? 68.616 68.497 -26.472 1.00 17.18 ? 943 GLN A O 1 ATOM 7394 C CB . GLN A 1 943 ? 71.158 66.611 -25.749 1.00 19.33 ? 943 GLN A CB 1 ATOM 7395 C CG . GLN A 1 943 ? 72.556 66.581 -25.139 1.00 23.95 ? 943 GLN A CG 1 ATOM 7396 C CD . GLN A 1 943 ? 72.804 65.322 -24.283 1.00 27.56 ? 943 GLN A CD 1 ATOM 7397 O OE1 . GLN A 1 943 ? 71.892 64.832 -23.589 1.00 29.02 ? 943 GLN A OE1 1 ATOM 7398 N NE2 . GLN A 1 943 ? 74.040 64.815 -24.312 1.00 26.44 ? 943 GLN A NE2 1 ATOM 7399 N N . GLY A 1 944 ? 69.234 67.226 -28.201 1.00 16.26 ? 944 GLY A N 1 ATOM 7400 C CA . GLY A 1 944 ? 67.900 67.295 -28.762 1.00 16.17 ? 944 GLY A CA 1 ATOM 7401 C C . GLY A 1 944 ? 66.838 66.299 -28.342 1.00 16.96 ? 944 GLY A C 1 ATOM 7402 O O . GLY A 1 944 ? 65.670 66.500 -28.671 1.00 17.29 ? 944 GLY A O 1 ATOM 7403 N N . GLN A 1 945 ? 67.206 65.247 -27.613 1.00 15.33 ? 945 GLN A N 1 ATOM 7404 C CA . GLN A 1 945 ? 66.208 64.253 -27.277 1.00 16.13 ? 945 GLN A CA 1 ATOM 7405 C C . GLN A 1 945 ? 66.650 63.321 -26.162 1.00 15.33 ? 945 GLN A C 1 ATOM 7406 O O . GLN A 1 945 ? 67.838 63.068 -25.972 1.00 14.93 ? 945 GLN A O 1 ATOM 7407 C CB . GLN A 1 945 ? 65.906 63.411 -28.516 1.00 17.64 ? 945 GLN A CB 1 ATOM 7408 C CG . GLN A 1 945 ? 64.735 62.425 -28.403 1.00 21.27 ? 945 GLN A CG 1 ATOM 7409 C CD . GLN A 1 945 ? 64.588 61.552 -29.677 1.00 23.20 ? 945 GLN A CD 1 ATOM 7410 O OE1 . GLN A 1 945 ? 65.333 60.588 -29.879 1.00 24.22 ? 945 GLN A OE1 1 ATOM 7411 N NE2 . GLN A 1 945 ? 63.640 61.914 -30.537 1.00 23.11 ? 945 GLN A NE2 1 ATOM 7412 N N . PHE A 1 946 ? 65.670 62.814 -25.434 1.00 13.78 ? 946 PHE A N 1 ATOM 7413 C CA . PHE A 1 946 ? 65.913 61.864 -24.374 1.00 12.45 ? 946 PHE A CA 1 ATOM 7414 C C . PHE A 1 946 ? 64.791 60.855 -24.457 1.00 12.68 ? 946 PHE A C 1 ATOM 7415 O O . PHE A 1 946 ? 63.627 61.231 -24.590 1.00 12.19 ? 946 PHE A O 1 ATOM 7416 C CB . PHE A 1 946 ? 65.876 62.538 -22.987 1.00 12.89 ? 946 PHE A CB 1 ATOM 7417 C CG . PHE A 1 946 ? 65.747 61.552 -21.837 1.00 12.75 ? 946 PHE A CG 1 ATOM 7418 C CD1 . PHE A 1 946 ? 66.815 60.713 -21.495 1.00 14.17 ? 946 PHE A CD1 1 ATOM 7419 C CD2 . PHE A 1 946 ? 64.525 61.397 -21.169 1.00 13.12 ? 946 PHE A CD2 1 ATOM 7420 C CE1 . PHE A 1 946 ? 66.672 59.698 -20.493 1.00 14.11 ? 946 PHE A CE1 1 ATOM 7421 C CE2 . PHE A 1 946 ? 64.357 60.408 -20.182 1.00 14.40 ? 946 PHE A CE2 1 ATOM 7422 C CZ . PHE A 1 946 ? 65.440 59.544 -19.843 1.00 14.10 ? 946 PHE A CZ 1 ATOM 7423 N N . GLY A 1 947 ? 65.142 59.577 -24.384 1.00 12.51 ? 947 GLY A N 1 ATOM 7424 C CA . GLY A 1 947 ? 64.131 58.539 -24.377 1.00 11.30 ? 947 GLY A CA 1 ATOM 7425 C C . GLY A 1 947 ? 63.817 57.958 -25.728 1.00 12.11 ? 947 GLY A C 1 ATOM 7426 O O . GLY A 1 947 ? 62.894 57.187 -25.833 1.00 11.96 ? 947 GLY A O 1 ATOM 7427 N N . GLY A 1 948 ? 64.591 58.312 -26.756 1.00 12.69 ? 948 GLY A N 1 ATOM 7428 C CA . GLY A 1 948 ? 64.334 57.794 -28.087 1.00 13.69 ? 948 GLY A CA 1 ATOM 7429 C C . GLY A 1 948 ? 64.356 56.282 -28.127 1.00 14.58 ? 948 GLY A C 1 ATOM 7430 O O . GLY A 1 948 ? 63.771 55.690 -29.009 1.00 15.21 ? 948 GLY A O 1 ATOM 7431 N N . ASP A 1 949 ? 65.018 55.647 -27.165 1.00 16.58 ? 949 ASP A N 1 ATOM 7432 C CA . ASP A 1 949 ? 65.084 54.179 -27.134 1.00 19.24 ? 949 ASP A CA 1 ATOM 7433 C C . ASP A 1 949 ? 64.089 53.545 -26.156 1.00 19.40 ? 949 ASP A C 1 ATOM 7434 O O . ASP A 1 949 ? 64.092 52.327 -25.968 1.00 18.91 ? 949 ASP A O 1 ATOM 7435 C CB . ASP A 1 949 ? 66.509 53.729 -26.777 1.00 22.02 ? 949 ASP A CB 1 ATOM 7436 C CG . ASP A 1 949 ? 66.971 54.267 -25.422 1.00 26.52 ? 949 ASP A CG 1 ATOM 7437 O OD1 . ASP A 1 949 ? 66.306 55.182 -24.830 1.00 28.31 ? 949 ASP A OD1 1 ATOM 7438 O OD2 . ASP A 1 949 ? 68.020 53.779 -24.948 1.00 28.91 ? 949 ASP A OD2 1 ATOM 7439 N N . HIS A 1 950 ? 63.255 54.369 -25.516 1.00 17.73 ? 950 HIS A N 1 ATOM 7440 C CA . HIS A 1 950 ? 62.258 53.858 -24.577 1.00 16.10 ? 950 HIS A CA 1 ATOM 7441 C C . HIS A 1 950 ? 61.221 53.112 -25.394 1.00 14.87 ? 950 HIS A C 1 ATOM 7442 O O . HIS A 1 950 ? 60.849 53.558 -26.457 1.00 14.93 ? 950 HIS A O 1 ATOM 7443 C CB . HIS A 1 950 ? 61.565 55.010 -23.845 1.00 16.08 ? 950 HIS A CB 1 ATOM 7444 C CG . HIS A 1 950 ? 62.425 55.675 -22.813 1.00 14.16 ? 950 HIS A CG 1 ATOM 7445 N ND1 . HIS A 1 950 ? 62.062 56.847 -22.189 1.00 13.31 ? 950 HIS A ND1 1 ATOM 7446 C CD2 . HIS A 1 950 ? 63.663 55.374 -22.362 1.00 14.28 ? 950 HIS A CD2 1 ATOM 7447 C CE1 . HIS A 1 950 ? 63.048 57.245 -21.405 1.00 13.41 ? 950 HIS A CE1 1 ATOM 7448 N NE2 . HIS A 1 950 ? 64.034 56.369 -21.495 1.00 15.04 ? 950 HIS A NE2 1 ATOM 7449 N N . PRO A 1 951 ? 60.772 51.957 -24.918 1.00 14.74 ? 951 PRO A N 1 ATOM 7450 C CA . PRO A 1 951 ? 59.764 51.159 -25.623 1.00 15.08 ? 951 PRO A CA 1 ATOM 7451 C C . PRO A 1 951 ? 58.469 51.962 -25.729 1.00 14.30 ? 951 PRO A C 1 ATOM 7452 O O . PRO A 1 951 ? 58.083 52.606 -24.767 1.00 13.70 ? 951 PRO A O 1 ATOM 7453 C CB . PRO A 1 951 ? 59.573 49.949 -24.709 1.00 15.96 ? 951 PRO A CB 1 ATOM 7454 C CG . PRO A 1 951 ? 60.888 49.835 -23.994 1.00 16.47 ? 951 PRO A CG 1 ATOM 7455 C CD . PRO A 1 951 ? 61.300 51.247 -23.733 1.00 15.66 ? 951 PRO A CD 1 ATOM 7456 N N . SER A 1 952 ? 57.813 51.916 -26.888 1.00 13.94 ? 952 SER A N 1 ATOM 7457 C CA . SER A 1 952 ? 56.548 52.608 -27.116 1.00 13.92 ? 952 SER A CA 1 ATOM 7458 C C . SER A 1 952 ? 55.481 51.545 -26.944 1.00 15.92 ? 952 SER A C 1 ATOM 7459 O O . SER A 1 952 ? 55.193 50.763 -27.881 1.00 17.24 ? 952 SER A O 1 ATOM 7460 C CB . SER A 1 952 ? 56.497 53.194 -28.529 1.00 14.17 ? 952 SER A CB 1 ATOM 7461 O OG . SER A 1 952 ? 55.350 54.008 -28.693 1.00 13.32 ? 952 SER A OG 1 ATOM 7462 N N . ALA A 1 953 ? 54.916 51.504 -25.734 1.00 15.17 ? 953 ALA A N 1 ATOM 7463 C CA . ALA A 1 953 ? 53.924 50.504 -25.341 1.00 14.31 ? 953 ALA A CA 1 ATOM 7464 C C . ALA A 1 953 ? 52.579 50.623 -26.012 1.00 14.23 ? 953 ALA A C 1 ATOM 7465 O O . ALA A 1 953 ? 52.201 51.709 -26.469 1.00 13.11 ? 953 ALA A O 1 ATOM 7466 C CB . ALA A 1 953 ? 53.725 50.564 -23.819 1.00 14.00 ? 953 ALA A CB 1 ATOM 7467 N N . ARG A 1 954 ? 51.830 49.515 -25.991 1.00 13.40 ? 954 ARG A N 1 ATOM 7468 C CA . ARG A 1 954 ? 50.492 49.471 -26.563 1.00 13.93 ? 954 ARG A CA 1 ATOM 7469 C C . ARG A 1 954 ? 49.657 50.574 -25.921 1.00 12.31 ? 954 ARG A C 1 ATOM 7470 O O . ARG A 1 954 ? 49.750 50.831 -24.705 1.00 9.93 ? 954 ARG A O 1 ATOM 7471 C CB . ARG A 1 954 ? 49.819 48.121 -26.325 1.00 16.85 ? 954 ARG A CB 1 ATOM 7472 C CG . ARG A 1 954 ? 48.411 48.115 -26.955 1.00 23.34 ? 954 ARG A CG 1 ATOM 7473 C CD . ARG A 1 954 ? 48.050 46.782 -27.610 1.00 26.78 ? 954 ARG A CD 1 ATOM 7474 N NE . ARG A 1 954 ? 47.544 45.790 -26.665 1.00 31.75 ? 954 ARG A NE 1 ATOM 7475 C CZ . ARG A 1 954 ? 46.362 45.871 -26.061 1.00 34.22 ? 954 ARG A CZ 1 ATOM 7476 N NH1 . ARG A 1 954 ? 45.577 46.918 -26.311 1.00 37.17 ? 954 ARG A NH1 1 ATOM 7477 N NH2 . ARG A 1 954 ? 45.944 44.904 -25.236 1.00 33.91 ? 954 ARG A NH2 1 ATOM 7478 N N . GLU A 1 955 ? 48.808 51.188 -26.740 1.00 10.97 ? 955 GLU A N 1 ATOM 7479 C CA . GLU A 1 955 ? 48.020 52.352 -26.325 1.00 12.41 ? 955 GLU A CA 1 ATOM 7480 C C . GLU A 1 955 ? 47.140 52.246 -25.090 1.00 10.83 ? 955 GLU A C 1 ATOM 7481 O O . GLU A 1 955 ? 46.824 53.278 -24.517 1.00 9.98 ? 955 GLU A O 1 ATOM 7482 C CB . GLU A 1 955 ? 47.150 52.832 -27.480 1.00 13.68 ? 955 GLU A CB 1 ATOM 7483 C CG . GLU A 1 955 ? 45.984 51.892 -27.739 1.00 16.53 ? 955 GLU A CG 1 ATOM 7484 C CD . GLU A 1 955 ? 45.136 52.291 -28.944 1.00 18.39 ? 955 GLU A CD 1 ATOM 7485 O OE1 . GLU A 1 955 ? 44.994 53.487 -29.213 1.00 20.03 ? 955 GLU A OE1 1 ATOM 7486 O OE2 . GLU A 1 955 ? 44.593 51.394 -29.618 1.00 22.26 ? 955 GLU A OE2 1 ATOM 7487 N N . ASP A 1 956 ? 46.722 51.041 -24.695 1.00 10.42 ? 956 ASP A N 1 ATOM 7488 C CA . ASP A 1 956 ? 45.855 50.915 -23.500 1.00 11.29 ? 956 ASP A CA 1 ATOM 7489 C C . ASP A 1 956 ? 46.657 50.739 -22.207 1.00 11.20 ? 956 ASP A C 1 ATOM 7490 O O . ASP A 1 956 ? 46.094 50.622 -21.110 1.00 12.08 ? 956 ASP A O 1 ATOM 7491 C CB . ASP A 1 956 ? 44.826 49.760 -23.647 1.00 11.41 ? 956 ASP A CB 1 ATOM 7492 C CG . ASP A 1 956 ? 45.479 48.394 -23.994 1.00 13.65 ? 956 ASP A CG 1 ATOM 7493 O OD1 . ASP A 1 956 ? 46.713 48.346 -24.152 1.00 12.68 ? 956 ASP A OD1 1 ATOM 7494 O OD2 . ASP A 1 956 ? 44.742 47.362 -24.120 1.00 12.74 ? 956 ASP A OD2 1 ATOM 7495 N N . LEU A 1 957 ? 47.973 50.738 -22.330 1.00 10.87 ? 957 LEU A N 1 ATOM 7496 C CA . LEU A 1 957 ? 48.845 50.603 -21.158 1.00 11.04 ? 957 LEU A CA 1 ATOM 7497 C C . LEU A 1 957 ? 49.419 51.940 -20.752 1.00 10.74 ? 957 LEU A C 1 ATOM 7498 O O . LEU A 1 957 ? 49.786 52.737 -21.610 1.00 8.73 ? 957 LEU A O 1 ATOM 7499 C CB . LEU A 1 957 ? 50.005 49.673 -21.480 1.00 11.98 ? 957 LEU A CB 1 ATOM 7500 C CG . LEU A 1 957 ? 50.863 49.197 -20.308 1.00 15.43 ? 957 LEU A CG 1 ATOM 7501 C CD1 . LEU A 1 957 ? 50.040 48.248 -19.398 1.00 14.82 ? 957 LEU A CD1 1 ATOM 7502 C CD2 . LEU A 1 957 ? 52.118 48.494 -20.862 1.00 15.32 ? 957 LEU A CD2 1 ATOM 7503 N N . ASP A 1 958 ? 49.524 52.176 -19.444 1.00 10.33 ? 958 ASP A N 1 ATOM 7504 C CA . ASP A 1 958 ? 50.134 53.415 -18.949 1.00 10.43 ? 958 ASP A CA 1 ATOM 7505 C C . ASP A 1 958 ? 51.081 53.130 -17.769 1.00 10.78 ? 958 ASP A C 1 ATOM 7506 O O . ASP A 1 958 ? 50.867 52.172 -17.025 1.00 11.85 ? 958 ASP A O 1 ATOM 7507 C CB . ASP A 1 958 ? 49.040 54.405 -18.475 1.00 9.59 ? 958 ASP A CB 1 ATOM 7508 C CG . ASP A 1 958 ? 49.576 55.831 -18.280 1.00 10.36 ? 958 ASP A CG 1 ATOM 7509 O OD1 . ASP A 1 958 ? 50.682 56.160 -18.774 1.00 7.51 ? 958 ASP A OD1 1 ATOM 7510 O OD2 . ASP A 1 958 ? 48.873 56.627 -17.624 1.00 10.69 ? 958 ASP A OD2 1 ATOM 7511 N N . VAL A 1 959 ? 52.157 53.913 -17.646 1.00 10.10 ? 959 VAL A N 1 ATOM 7512 C CA . VAL A 1 959 ? 53.045 53.820 -16.477 1.00 10.59 ? 959 VAL A CA 1 ATOM 7513 C C . VAL A 1 959 ? 52.455 54.940 -15.598 1.00 10.01 ? 959 VAL A C 1 ATOM 7514 O O . VAL A 1 959 ? 52.877 56.097 -15.669 1.00 9.76 ? 959 VAL A O 1 ATOM 7515 C CB . VAL A 1 959 ? 54.540 54.133 -16.826 1.00 12.04 ? 959 VAL A CB 1 ATOM 7516 C CG1 . VAL A 1 959 ? 55.367 54.411 -15.534 1.00 10.53 ? 959 VAL A CG1 1 ATOM 7517 C CG2 . VAL A 1 959 ? 55.161 52.899 -17.561 1.00 12.26 ? 959 VAL A CG2 1 ATOM 7518 N N . SER A 1 960 ? 51.435 54.601 -14.816 1.00 9.04 ? 960 SER A N 1 ATOM 7519 C CA . SER A 1 960 ? 50.749 55.572 -13.963 1.00 8.05 ? 960 SER A CA 1 ATOM 7520 C C . SER A 1 960 ? 51.677 56.310 -12.987 1.00 8.86 ? 960 SER A C 1 ATOM 7521 O O . SER A 1 960 ? 51.495 57.516 -12.719 1.00 8.20 ? 960 SER A O 1 ATOM 7522 C CB . SER A 1 960 ? 49.642 54.856 -13.175 1.00 7.82 ? 960 SER A CB 1 ATOM 7523 O OG . SER A 1 960 ? 48.826 54.115 -14.082 1.00 8.15 ? 960 SER A OG 1 ATOM 7524 N N . VAL A 1 961 ? 52.654 55.576 -12.462 1.00 9.08 ? 961 VAL A N 1 ATOM 7525 C CA . VAL A 1 961 ? 53.627 56.117 -11.499 1.00 8.31 ? 961 VAL A CA 1 ATOM 7526 C C . VAL A 1 961 ? 55.032 55.572 -11.776 1.00 9.63 ? 961 VAL A C 1 ATOM 7527 O O . VAL A 1 961 ? 55.209 54.365 -12.029 1.00 8.16 ? 961 VAL A O 1 ATOM 7528 C CB . VAL A 1 961 ? 53.305 55.682 -10.000 1.00 10.24 ? 961 VAL A CB 1 ATOM 7529 C CG1 . VAL A 1 961 ? 54.414 56.209 -9.039 1.00 9.73 ? 961 VAL A CG1 1 ATOM 7530 C CG2 . VAL A 1 961 ? 51.917 56.233 -9.530 1.00 7.16 ? 961 VAL A CG2 1 ATOM 7531 N N . MET A 1 962 ? 56.017 56.471 -11.758 1.00 8.77 ? 962 MET A N 1 ATOM 7532 C CA . MET A 1 962 ? 57.397 56.066 -11.831 1.00 9.59 ? 962 MET A CA 1 ATOM 7533 C C . MET A 1 962 ? 57.997 56.838 -10.659 1.00 10.29 ? 962 MET A C 1 ATOM 7534 O O . MET A 1 962 ? 57.974 58.078 -10.637 1.00 10.50 ? 962 MET A O 1 ATOM 7535 C CB . MET A 1 962 ? 58.079 56.475 -13.142 1.00 10.49 ? 962 MET A CB 1 ATOM 7536 C CG . MET A 1 962 ? 59.513 55.993 -13.131 1.00 11.22 ? 962 MET A CG 1 ATOM 7537 S SD . MET A 1 962 ? 60.349 56.383 -14.651 1.00 11.75 ? 962 MET A SD 1 ATOM 7538 C CE . MET A 1 962 ? 62.069 55.837 -14.255 1.00 14.71 ? 962 MET A CE 1 ATOM 7539 N N . ARG A 1 963 ? 58.503 56.114 -9.654 1.00 10.13 ? 963 ARG A N 1 ATOM 7540 C CA . ARG A 1 963 ? 59.053 56.783 -8.495 1.00 9.39 ? 963 ARG A CA 1 ATOM 7541 C C . ARG A 1 963 ? 60.308 56.106 -7.954 1.00 8.57 ? 963 ARG A C 1 ATOM 7542 O O . ARG A 1 963 ? 60.269 54.936 -7.606 1.00 7.52 ? 963 ARG A O 1 ATOM 7543 C CB . ARG A 1 963 ? 57.968 56.852 -7.366 1.00 10.05 ? 963 ARG A CB 1 ATOM 7544 C CG . ARG A 1 963 ? 58.470 57.352 -5.974 1.00 9.23 ? 963 ARG A CG 1 ATOM 7545 C CD . ARG A 1 963 ? 57.365 57.312 -4.869 1.00 9.71 ? 963 ARG A CD 1 ATOM 7546 N NE . ARG A 1 963 ? 56.163 58.013 -5.331 1.00 10.25 ? 963 ARG A NE 1 ATOM 7547 C CZ . ARG A 1 963 ? 54.922 57.526 -5.270 1.00 8.41 ? 963 ARG A CZ 1 ATOM 7548 N NH1 . ARG A 1 963 ? 54.684 56.336 -4.724 1.00 7.90 ? 963 ARG A NH1 1 ATOM 7549 N NH2 . ARG A 1 963 ? 53.930 58.178 -5.874 1.00 6.75 ? 963 ARG A NH2 1 ATOM 7550 N N . ARG A 1 964 ? 61.413 56.847 -7.871 1.00 9.22 ? 964 ARG A N 1 ATOM 7551 C CA . ARG A 1 964 ? 62.634 56.280 -7.286 1.00 9.43 ? 964 ARG A CA 1 ATOM 7552 C C . ARG A 1 964 ? 62.342 56.252 -5.785 1.00 9.61 ? 964 ARG A C 1 ATOM 7553 O O . ARG A 1 964 ? 61.936 57.259 -5.179 1.00 10.57 ? 964 ARG A O 1 ATOM 7554 C CB . ARG A 1 964 ? 63.882 57.137 -7.575 1.00 9.36 ? 964 ARG A CB 1 ATOM 7555 C CG . ARG A 1 964 ? 65.174 56.553 -6.917 1.00 10.52 ? 964 ARG A CG 1 ATOM 7556 C CD . ARG A 1 964 ? 66.454 57.288 -7.386 1.00 11.50 ? 964 ARG A CD 1 ATOM 7557 N NE . ARG A 1 964 ? 66.664 57.164 -8.831 1.00 12.01 ? 964 ARG A NE 1 ATOM 7558 C CZ . ARG A 1 964 ? 67.449 56.258 -9.410 1.00 12.76 ? 964 ARG A CZ 1 ATOM 7559 N NH1 . ARG A 1 964 ? 68.113 55.373 -8.670 1.00 12.39 ? 964 ARG A NH1 1 ATOM 7560 N NH2 . ARG A 1 964 ? 67.601 56.261 -10.734 1.00 13.01 ? 964 ARG A NH2 1 ATOM 7561 N N . LEU A 1 965 ? 62.548 55.087 -5.195 1.00 9.60 ? 965 LEU A N 1 ATOM 7562 C CA . LEU A 1 965 ? 62.230 54.845 -3.791 1.00 9.36 ? 965 LEU A CA 1 ATOM 7563 C C . LEU A 1 965 ? 63.395 54.951 -2.798 1.00 10.82 ? 965 LEU A C 1 ATOM 7564 O O . LEU A 1 965 ? 63.164 54.873 -1.579 1.00 10.02 ? 965 LEU A O 1 ATOM 7565 C CB . LEU A 1 965 ? 61.621 53.440 -3.673 1.00 8.25 ? 965 LEU A CB 1 ATOM 7566 C CG . LEU A 1 965 ? 60.372 53.126 -4.528 1.00 9.30 ? 965 LEU A CG 1 ATOM 7567 C CD1 . LEU A 1 965 ? 60.034 51.602 -4.408 1.00 6.53 ? 965 LEU A CD1 1 ATOM 7568 C CD2 . LEU A 1 965 ? 59.196 53.983 -4.054 1.00 8.34 ? 965 LEU A CD2 1 ATOM 7569 N N . THR A 1 966 ? 64.618 55.117 -3.315 1.00 9.89 ? 966 THR A N 1 ATOM 7570 C CA . THR A 1 966 ? 65.817 55.203 -2.489 1.00 12.07 ? 966 THR A CA 1 ATOM 7571 C C . THR A 1 966 ? 66.576 56.504 -2.687 1.00 12.12 ? 966 THR A C 1 ATOM 7572 O O . THR A 1 966 ? 66.556 57.062 -3.793 1.00 12.45 ? 966 THR A O 1 ATOM 7573 C CB . THR A 1 966 ? 66.812 54.084 -2.848 1.00 10.84 ? 966 THR A CB 1 ATOM 7574 O OG1 . THR A 1 966 ? 67.013 54.062 -4.262 1.00 13.70 ? 966 THR A OG1 1 ATOM 7575 C CG2 . THR A 1 966 ? 66.316 52.731 -2.352 1.00 11.87 ? 966 THR A CG2 1 ATOM 7576 N N . LYS A 1 967 ? 67.231 56.963 -1.623 1.00 11.78 ? 967 LYS A N 1 ATOM 7577 C CA . LYS A 1 967 ? 68.056 58.165 -1.650 1.00 14.54 ? 967 LYS A CA 1 ATOM 7578 C C . LYS A 1 967 ? 69.431 57.759 -2.193 1.00 14.73 ? 967 LYS A C 1 ATOM 7579 O O . LYS A 1 967 ? 69.737 56.564 -2.271 1.00 14.39 ? 967 LYS A O 1 ATOM 7580 C CB . LYS A 1 967 ? 68.165 58.781 -0.252 1.00 15.61 ? 967 LYS A CB 1 ATOM 7581 C CG . LYS A 1 967 ? 66.810 59.318 0.239 1.00 19.50 ? 967 LYS A CG 1 ATOM 7582 C CD . LYS A 1 967 ? 66.968 60.171 1.492 1.00 21.99 ? 967 LYS A CD 1 ATOM 7583 C CE . LYS A 1 967 ? 65.784 61.078 1.688 1.00 25.20 ? 967 LYS A CE 1 ATOM 7584 N NZ . LYS A 1 967 ? 66.047 62.071 2.797 1.00 28.57 ? 967 LYS A NZ 1 ATOM 7585 N N . SER A 1 968 ? 70.248 58.737 -2.571 1.00 15.64 ? 968 SER A N 1 ATOM 7586 C CA . SER A 1 968 ? 71.545 58.455 -3.194 1.00 17.48 ? 968 SER A CA 1 ATOM 7587 C C . SER A 1 968 ? 72.526 57.613 -2.372 1.00 17.44 ? 968 SER A C 1 ATOM 7588 O O . SER A 1 968 ? 73.334 56.871 -2.936 1.00 18.58 ? 968 SER A O 1 ATOM 7589 C CB . SER A 1 968 ? 72.242 59.770 -3.616 1.00 17.45 ? 968 SER A CB 1 ATOM 7590 O OG . SER A 1 968 ? 72.623 60.509 -2.478 1.00 21.81 ? 968 SER A OG 1 ATOM 7591 N N . SER A 1 969 ? 72.445 57.704 -1.054 1.00 18.39 ? 969 SER A N 1 ATOM 7592 C CA . SER A 1 969 ? 73.359 56.941 -0.210 1.00 19.82 ? 969 SER A CA 1 ATOM 7593 C C . SER A 1 969 ? 73.060 55.454 -0.155 1.00 19.98 ? 969 SER A C 1 ATOM 7594 O O . SER A 1 969 ? 73.827 54.712 0.443 1.00 21.15 ? 969 SER A O 1 ATOM 7595 C CB . SER A 1 969 ? 73.357 57.492 1.209 1.00 20.70 ? 969 SER A CB 1 ATOM 7596 O OG . SER A 1 969 ? 72.091 57.243 1.788 1.00 26.49 ? 969 SER A OG 1 ATOM 7597 N N . ALA A 1 970 ? 71.963 54.996 -0.759 1.00 19.10 ? 970 ALA A N 1 ATOM 7598 C CA . ALA A 1 970 ? 71.647 53.561 -0.743 1.00 17.93 ? 970 ALA A CA 1 ATOM 7599 C C . ALA A 1 970 ? 72.446 52.787 -1.779 1.00 18.24 ? 970 ALA A C 1 ATOM 7600 O O . ALA A 1 970 ? 72.355 53.070 -2.978 1.00 17.29 ? 970 ALA A O 1 ATOM 7601 C CB . ALA A 1 970 ? 70.153 53.330 -1.005 1.00 17.36 ? 970 ALA A CB 1 ATOM 7602 N N . LYS A 1 971 ? 73.187 51.781 -1.331 1.00 18.11 ? 971 LYS A N 1 ATOM 7603 C CA . LYS A 1 971 ? 73.980 50.969 -2.247 1.00 20.01 ? 971 LYS A CA 1 ATOM 7604 C C . LYS A 1 971 ? 73.103 50.352 -3.324 1.00 19.56 ? 971 LYS A C 1 ATOM 7605 O O . LYS A 1 971 ? 73.480 50.302 -4.493 1.00 20.89 ? 971 LYS A O 1 ATOM 7606 C CB . LYS A 1 971 ? 74.672 49.842 -1.489 1.00 22.07 ? 971 LYS A CB 1 ATOM 7607 C CG . LYS A 1 971 ? 75.734 49.144 -2.307 1.00 24.63 ? 971 LYS A CG 1 ATOM 7608 C CD . LYS A 1 971 ? 76.459 48.087 -1.466 1.00 28.14 ? 971 LYS A CD 1 ATOM 7609 C CE . LYS A 1 971 ? 77.715 47.602 -2.194 1.00 31.10 ? 971 LYS A CE 1 ATOM 7610 N NZ . LYS A 1 971 ? 77.507 47.499 -3.689 1.00 33.77 ? 971 LYS A NZ 1 ATOM 7611 N N . THR A 1 972 ? 71.952 49.827 -2.930 1.00 18.55 ? 972 THR A N 1 ATOM 7612 C CA . THR A 1 972 ? 71.071 49.236 -3.921 1.00 18.35 ? 972 THR A CA 1 ATOM 7613 C C . THR A 1 972 ? 69.943 50.218 -4.205 1.00 17.20 ? 972 THR A C 1 ATOM 7614 O O . THR A 1 972 ? 69.127 50.496 -3.342 1.00 17.37 ? 972 THR A O 1 ATOM 7615 C CB . THR A 1 972 ? 70.468 47.881 -3.441 1.00 19.54 ? 972 THR A CB 1 ATOM 7616 O OG1 . THR A 1 972 ? 71.533 46.962 -3.191 1.00 20.89 ? 972 THR A OG1 1 ATOM 7617 C CG2 . THR A 1 972 ? 69.576 47.257 -4.527 1.00 18.75 ? 972 THR A CG2 1 ATOM 7618 N N . GLN A 1 973 ? 69.949 50.796 -5.396 1.00 15.33 ? 973 GLN A N 1 ATOM 7619 C CA . GLN A 1 973 ? 68.895 51.705 -5.766 1.00 15.42 ? 973 GLN A CA 1 ATOM 7620 C C . GLN A 1 973 ? 67.631 50.929 -6.148 1.00 14.36 ? 973 GLN A C 1 ATOM 7621 O O . GLN A 1 973 ? 67.700 49.828 -6.700 1.00 14.96 ? 973 GLN A O 1 ATOM 7622 C CB . GLN A 1 973 ? 69.333 52.573 -6.934 1.00 13.62 ? 973 GLN A CB 1 ATOM 7623 C CG . GLN A 1 973 ? 70.376 53.623 -6.564 1.00 14.11 ? 973 GLN A CG 1 ATOM 7624 C CD . GLN A 1 973 ? 69.883 54.603 -5.536 1.00 14.68 ? 973 GLN A CD 1 ATOM 7625 O OE1 . GLN A 1 973 ? 68.869 55.277 -5.745 1.00 14.48 ? 973 GLN A OE1 1 ATOM 7626 N NE2 . GLN A 1 973 ? 70.600 54.703 -4.418 1.00 13.21 ? 973 GLN A NE2 1 ATOM 7627 N N . ARG A 1 974 ? 66.481 51.523 -5.842 1.00 13.94 ? 974 ARG A N 1 ATOM 7628 C CA . ARG A 1 974 ? 65.199 50.932 -6.161 1.00 13.00 ? 974 ARG A CA 1 ATOM 7629 C C . ARG A 1 974 ? 64.264 51.938 -6.795 1.00 11.75 ? 974 ARG A C 1 ATOM 7630 O O . ARG A 1 974 ? 64.137 53.095 -6.338 1.00 10.86 ? 974 ARG A O 1 ATOM 7631 C CB . ARG A 1 974 ? 64.534 50.362 -4.916 1.00 14.29 ? 974 ARG A CB 1 ATOM 7632 C CG . ARG A 1 974 ? 65.381 49.347 -4.129 1.00 15.20 ? 974 ARG A CG 1 ATOM 7633 C CD . ARG A 1 974 ? 64.781 49.162 -2.716 1.00 18.02 ? 974 ARG A CD 1 ATOM 7634 N NE . ARG A 1 974 ? 63.562 48.363 -2.764 1.00 21.24 ? 974 ARG A NE 1 ATOM 7635 C CZ . ARG A 1 974 ? 62.422 48.678 -2.162 1.00 20.91 ? 974 ARG A CZ 1 ATOM 7636 N NH1 . ARG A 1 974 ? 62.322 49.789 -1.446 1.00 23.06 ? 974 ARG A NH1 1 ATOM 7637 N NH2 . ARG A 1 974 ? 61.377 47.882 -2.292 1.00 21.30 ? 974 ARG A NH2 1 ATOM 7638 N N . VAL A 1 975 ? 63.604 51.490 -7.852 1.00 11.01 ? 975 VAL A N 1 ATOM 7639 C CA . VAL A 1 975 ? 62.652 52.337 -8.560 1.00 10.52 ? 975 VAL A CA 1 ATOM 7640 C C . VAL A 1 975 ? 61.316 51.620 -8.677 1.00 10.44 ? 975 VAL A C 1 ATOM 7641 O O . VAL A 1 975 ? 61.243 50.458 -9.124 1.00 10.66 ? 975 VAL A O 1 ATOM 7642 C CB . VAL A 1 975 ? 63.180 52.716 -9.962 1.00 11.68 ? 975 VAL A CB 1 ATOM 7643 C CG1 . VAL A 1 975 ? 62.145 53.650 -10.704 1.00 9.95 ? 975 VAL A CG1 1 ATOM 7644 C CG2 . VAL A 1 975 ? 64.492 53.477 -9.808 1.00 10.55 ? 975 VAL A CG2 1 ATOM 7645 N N . GLY A 1 976 ? 60.261 52.306 -8.243 1.00 10.08 ? 976 GLY A N 1 ATOM 7646 C CA . GLY A 1 976 ? 58.932 51.719 -8.286 1.00 9.57 ? 976 GLY A CA 1 ATOM 7647 C C . GLY A 1 976 ? 58.097 52.230 -9.456 1.00 9.84 ? 976 GLY A C 1 ATOM 7648 O O . GLY A 1 976 ? 58.174 53.418 -9.849 1.00 8.84 ? 976 GLY A O 1 ATOM 7649 N N . TYR A 1 977 ? 57.318 51.312 -10.019 1.00 8.80 ? 977 TYR A N 1 ATOM 7650 C CA . TYR A 1 977 ? 56.419 51.598 -11.118 1.00 10.23 ? 977 TYR A CA 1 ATOM 7651 C C . TYR A 1 977 ? 55.011 51.054 -10.871 1.00 10.10 ? 977 TYR A C 1 ATOM 7652 O O . TYR A 1 977 ? 54.847 49.914 -10.413 1.00 9.26 ? 977 TYR A O 1 ATOM 7653 C CB . TYR A 1 977 ? 56.892 50.942 -12.435 1.00 9.90 ? 977 TYR A CB 1 ATOM 7654 C CG . TYR A 1 977 ? 58.290 51.303 -12.866 1.00 12.03 ? 977 TYR A CG 1 ATOM 7655 C CD1 . TYR A 1 977 ? 59.394 50.623 -12.350 1.00 11.54 ? 977 TYR A CD1 1 ATOM 7656 C CD2 . TYR A 1 977 ? 58.507 52.321 -13.808 1.00 10.97 ? 977 TYR A CD2 1 ATOM 7657 C CE1 . TYR A 1 977 ? 60.701 50.950 -12.761 1.00 13.30 ? 977 TYR A CE1 1 ATOM 7658 C CE2 . TYR A 1 977 ? 59.785 52.653 -14.231 1.00 11.99 ? 977 TYR A CE2 1 ATOM 7659 C CZ . TYR A 1 977 ? 60.889 51.972 -13.708 1.00 13.34 ? 977 TYR A CZ 1 ATOM 7660 O OH . TYR A 1 977 ? 62.167 52.338 -14.104 1.00 13.37 ? 977 TYR A OH 1 ATOM 7661 N N . VAL A 1 978 ? 54.006 51.861 -11.187 1.00 8.93 ? 978 VAL A N 1 ATOM 7662 C CA . VAL A 1 978 ? 52.620 51.403 -11.107 1.00 9.04 ? 978 VAL A CA 1 ATOM 7663 C C . VAL A 1 978 ? 52.193 51.348 -12.584 1.00 9.31 ? 978 VAL A C 1 ATOM 7664 O O . VAL A 1 978 ? 52.298 52.353 -13.283 1.00 8.51 ? 978 VAL A O 1 ATOM 7665 C CB . VAL A 1 978 ? 51.721 52.372 -10.324 1.00 9.54 ? 978 VAL A CB 1 ATOM 7666 C CG1 . VAL A 1 978 ? 50.273 51.896 -10.398 1.00 10.34 ? 978 VAL A CG1 1 ATOM 7667 C CG2 . VAL A 1 978 ? 52.189 52.406 -8.836 1.00 9.67 ? 978 VAL A CG2 1 ATOM 7668 N N . LEU A 1 979 ? 51.780 50.165 -13.056 1.00 8.60 ? 979 LEU A N 1 ATOM 7669 C CA . LEU A 1 979 ? 51.366 49.971 -14.450 1.00 11.99 ? 979 LEU A CA 1 ATOM 7670 C C . LEU A 1 979 ? 49.878 49.710 -14.510 1.00 12.29 ? 979 LEU A C 1 ATOM 7671 O O . LEU A 1 979 ? 49.392 48.812 -13.844 1.00 13.11 ? 979 LEU A O 1 ATOM 7672 C CB . LEU A 1 979 ? 52.040 48.761 -15.085 1.00 14.06 ? 979 LEU A CB 1 ATOM 7673 C CG . LEU A 1 979 ? 53.323 48.789 -15.913 1.00 19.30 ? 979 LEU A CG 1 ATOM 7674 C CD1 . LEU A 1 979 ? 53.365 47.461 -16.722 1.00 21.04 ? 979 LEU A CD1 1 ATOM 7675 C CD2 . LEU A 1 979 ? 53.306 49.935 -16.898 1.00 19.48 ? 979 LEU A CD2 1 ATOM 7676 N N . HIS A 1 980 ? 49.162 50.465 -15.325 1.00 11.07 ? 980 HIS A N 1 ATOM 7677 C CA . HIS A 1 980 ? 47.724 50.267 -15.426 1.00 11.32 ? 980 HIS A CA 1 ATOM 7678 C C . HIS A 1 980 ? 47.345 50.023 -16.872 1.00 11.18 ? 980 HIS A C 1 ATOM 7679 O O . HIS A 1 980 ? 47.829 50.748 -17.749 1.00 11.70 ? 980 HIS A O 1 ATOM 7680 C CB . HIS A 1 980 ? 46.956 51.513 -14.949 1.00 11.52 ? 980 HIS A CB 1 ATOM 7681 C CG . HIS A 1 980 ? 45.480 51.407 -15.184 1.00 13.65 ? 980 HIS A CG 1 ATOM 7682 N ND1 . HIS A 1 980 ? 44.675 50.558 -14.454 1.00 12.65 ? 980 HIS A ND1 1 ATOM 7683 C CD2 . HIS A 1 980 ? 44.683 51.952 -16.135 1.00 13.87 ? 980 HIS A CD2 1 ATOM 7684 C CE1 . HIS A 1 980 ? 43.450 50.579 -14.942 1.00 13.30 ? 980 HIS A CE1 1 ATOM 7685 N NE2 . HIS A 1 980 ? 43.425 51.417 -15.965 1.00 15.28 ? 980 HIS A NE2 1 ATOM 7686 N N . ARG A 1 981 ? 46.529 48.999 -17.136 1.00 11.00 ? 981 ARG A N 1 ATOM 7687 C CA . ARG A 1 981 ? 46.046 48.782 -18.499 1.00 11.58 ? 981 ARG A CA 1 ATOM 7688 C C . ARG A 1 981 ? 44.542 48.955 -18.437 1.00 11.68 ? 981 ARG A C 1 ATOM 7689 O O . ARG A 1 981 ? 43.870 48.312 -17.626 1.00 10.88 ? 981 ARG A O 1 ATOM 7690 C CB . ARG A 1 981 ? 46.344 47.383 -19.063 1.00 13.60 ? 981 ARG A CB 1 ATOM 7691 C CG . ARG A 1 981 ? 46.247 47.376 -20.624 1.00 16.84 ? 981 ARG A CG 1 ATOM 7692 C CD . ARG A 1 981 ? 46.241 45.988 -21.251 1.00 20.36 ? 981 ARG A CD 1 ATOM 7693 N NE . ARG A 1 981 ? 47.527 45.347 -21.075 1.00 24.26 ? 981 ARG A NE 1 ATOM 7694 C CZ . ARG A 1 981 ? 48.510 45.346 -21.986 1.00 26.85 ? 981 ARG A CZ 1 ATOM 7695 N NH1 . ARG A 1 981 ? 48.371 45.958 -23.173 1.00 25.72 ? 981 ARG A NH1 1 ATOM 7696 N NH2 . ARG A 1 981 ? 49.653 44.717 -21.709 1.00 27.17 ? 981 ARG A NH2 1 ATOM 7697 N N . THR A 1 982 ? 44.008 49.845 -19.278 1.00 11.39 ? 982 THR A N 1 ATOM 7698 C CA . THR A 1 982 ? 42.571 50.079 -19.303 1.00 11.14 ? 982 THR A CA 1 ATOM 7699 C C . THR A 1 982 ? 42.041 49.057 -20.315 1.00 11.06 ? 982 THR A C 1 ATOM 7700 O O . THR A 1 982 ? 42.775 48.144 -20.703 1.00 10.06 ? 982 THR A O 1 ATOM 7701 C CB . THR A 1 982 ? 42.272 51.521 -19.750 1.00 11.20 ? 982 THR A CB 1 ATOM 7702 O OG1 . THR A 1 982 ? 40.869 51.768 -19.663 1.00 13.18 ? 982 THR A OG1 1 ATOM 7703 C CG2 . THR A 1 982 ? 42.752 51.759 -21.208 1.00 11.19 ? 982 THR A CG2 1 ATOM 7704 N N . ASN A 1 983 ? 40.777 49.165 -20.709 1.00 10.18 ? 983 ASN A N 1 ATOM 7705 C CA . ASN A 1 983 ? 40.254 48.232 -21.721 1.00 11.06 ? 983 ASN A CA 1 ATOM 7706 C C . ASN A 1 983 ? 39.522 49.070 -22.773 1.00 11.71 ? 983 ASN A C 1 ATOM 7707 O O . ASN A 1 983 ? 38.572 49.805 -22.454 1.00 10.99 ? 983 ASN A O 1 ATOM 7708 C CB . ASN A 1 983 ? 39.269 47.229 -21.139 1.00 10.29 ? 983 ASN A CB 1 ATOM 7709 C CG . ASN A 1 983 ? 38.726 46.257 -22.206 1.00 11.16 ? 983 ASN A CG 1 ATOM 7710 O OD1 . ASN A 1 983 ? 39.437 45.371 -22.632 1.00 11.27 ? 983 ASN A OD1 1 ATOM 7711 N ND2 . ASN A 1 983 ? 37.481 46.441 -22.628 1.00 7.89 ? 983 ASN A ND2 1 ATOM 7712 N N . LEU A 1 984 ? 39.969 48.961 -24.012 1.00 12.91 ? 984 LEU A N 1 ATOM 7713 C CA . LEU A 1 984 ? 39.381 49.733 -25.093 1.00 15.12 ? 984 LEU A CA 1 ATOM 7714 C C . LEU A 1 984 ? 38.581 48.838 -26.020 1.00 16.24 ? 984 LEU A C 1 ATOM 7715 O O . LEU A 1 984 ? 38.940 47.684 -26.259 1.00 16.06 ? 984 LEU A O 1 ATOM 7716 C CB . LEU A 1 984 ? 40.487 50.457 -25.868 1.00 14.94 ? 984 LEU A CB 1 ATOM 7717 C CG . LEU A 1 984 ? 41.414 51.378 -25.027 1.00 15.35 ? 984 LEU A CG 1 ATOM 7718 C CD1 . LEU A 1 984 ? 42.594 51.862 -25.901 1.00 13.84 ? 984 LEU A CD1 1 ATOM 7719 C CD2 . LEU A 1 984 ? 40.628 52.572 -24.474 1.00 14.84 ? 984 LEU A CD2 1 ATOM 7720 N N . MET A 1 985 ? 37.476 49.364 -26.533 1.00 18.15 ? 985 MET A N 1 ATOM 7721 C CA . MET A 1 985 ? 36.645 48.575 -27.439 1.00 19.89 ? 985 MET A CA 1 ATOM 7722 C C . MET A 1 985 ? 37.339 48.218 -28.743 1.00 20.87 ? 985 MET A C 1 ATOM 7723 O O . MET A 1 985 ? 38.072 49.026 -29.308 1.00 20.83 ? 985 MET A O 1 ATOM 7724 C CB . MET A 1 985 ? 35.365 49.318 -27.774 1.00 19.99 ? 985 MET A CB 1 ATOM 7725 C CG . MET A 1 985 ? 34.535 49.593 -26.578 1.00 21.84 ? 985 MET A CG 1 ATOM 7726 S SD . MET A 1 985 ? 32.823 49.508 -26.989 1.00 23.85 ? 985 MET A SD 1 ATOM 7727 C CE . MET A 1 985 ? 32.584 51.055 -27.867 1.00 22.31 ? 985 MET A CE 1 ATOM 7728 N N . GLN A 1 986 ? 37.101 46.985 -29.192 1.00 22.74 ? 986 GLN A N 1 ATOM 7729 C CA . GLN A 1 986 ? 37.624 46.457 -30.460 1.00 23.44 ? 986 GLN A CA 1 ATOM 7730 C C . GLN A 1 986 ? 36.590 46.953 -31.478 1.00 21.88 ? 986 GLN A C 1 ATOM 7731 O O . GLN A 1 986 ? 35.424 46.528 -31.413 1.00 20.46 ? 986 GLN A O 1 ATOM 7732 C CB . GLN A 1 986 ? 37.571 44.917 -30.460 1.00 27.50 ? 986 GLN A CB 1 ATOM 7733 C CG . GLN A 1 986 ? 38.414 44.195 -29.430 1.00 31.87 ? 986 GLN A CG 1 ATOM 7734 C CD . GLN A 1 986 ? 39.894 44.310 -29.708 1.00 35.79 ? 986 GLN A CD 1 ATOM 7735 O OE1 . GLN A 1 986 ? 40.543 45.277 -29.302 1.00 40.38 ? 986 GLN A OE1 1 ATOM 7736 N NE2 . GLN A 1 986 ? 40.444 43.323 -30.414 1.00 38.02 ? 986 GLN A NE2 1 ATOM 7737 N N . CYS A 1 987 ? 36.990 47.834 -32.394 1.00 20.16 ? 987 CYS A N 1 ATOM 7738 C CA . CYS A 1 987 ? 36.044 48.353 -33.370 1.00 20.40 ? 987 CYS A CA 1 ATOM 7739 C C . CYS A 1 987 ? 36.489 48.156 -34.814 1.00 22.35 ? 987 CYS A C 1 ATOM 7740 O O . CYS A 1 987 ? 36.023 48.865 -35.709 1.00 21.89 ? 987 CYS A O 1 ATOM 7741 C CB . CYS A 1 987 ? 35.749 49.840 -33.126 1.00 19.24 ? 987 CYS A CB 1 ATOM 7742 S SG . CYS A 1 987 ? 35.094 50.282 -31.473 1.00 17.41 ? 987 CYS A SG 1 ATOM 7743 N N . GLY A 1 988 ? 37.378 47.183 -35.039 1.00 24.17 ? 988 GLY A N 1 ATOM 7744 C CA . GLY A 1 988 ? 37.807 46.889 -36.388 1.00 28.38 ? 988 GLY A CA 1 ATOM 7745 C C . GLY A 1 988 ? 39.079 47.550 -36.842 1.00 31.97 ? 988 GLY A C 1 ATOM 7746 O O . GLY A 1 988 ? 39.534 47.310 -37.972 1.00 31.55 ? 988 GLY A O 1 ATOM 7747 N N . THR A 1 989 ? 39.657 48.394 -35.993 1.00 35.27 ? 989 THR A N 1 ATOM 7748 C CA . THR A 1 989 ? 40.915 49.043 -36.363 1.00 39.14 ? 989 THR A CA 1 ATOM 7749 C C . THR A 1 989 ? 42.051 48.069 -36.069 1.00 42.16 ? 989 THR A C 1 ATOM 7750 O O . THR A 1 989 ? 42.245 47.656 -34.922 1.00 42.74 ? 989 THR A O 1 ATOM 7751 C CB . THR A 1 989 ? 41.135 50.319 -35.576 1.00 38.65 ? 989 THR A CB 1 ATOM 7752 O OG1 . THR A 1 989 ? 40.024 51.195 -35.782 1.00 39.40 ? 989 THR A OG1 1 ATOM 7753 C CG2 . THR A 1 989 ? 42.394 50.997 -36.037 1.00 39.59 ? 989 THR A CG2 1 ATOM 7754 N N . PRO A 1 990 ? 42.813 47.676 -37.107 1.00 45.38 ? 990 PRO A N 1 ATOM 7755 C CA . PRO A 1 990 ? 43.921 46.736 -36.900 1.00 47.69 ? 990 PRO A CA 1 ATOM 7756 C C . PRO A 1 990 ? 44.892 47.148 -35.789 1.00 50.33 ? 990 PRO A C 1 ATOM 7757 O O . PRO A 1 990 ? 45.290 46.303 -34.973 1.00 50.91 ? 990 PRO A O 1 ATOM 7758 C CB . PRO A 1 990 ? 44.588 46.674 -38.275 1.00 47.45 ? 990 PRO A CB 1 ATOM 7759 C CG . PRO A 1 990 ? 43.433 46.896 -39.220 1.00 46.95 ? 990 PRO A CG 1 ATOM 7760 C CD . PRO A 1 990 ? 42.690 48.039 -38.532 1.00 45.70 ? 990 PRO A CD 1 ATOM 7761 N N . GLU A 1 991 ? 45.259 48.434 -35.746 1.00 52.51 ? 991 GLU A N 1 ATOM 7762 C CA . GLU A 1 991 ? 46.194 48.952 -34.728 1.00 55.25 ? 991 GLU A CA 1 ATOM 7763 C C . GLU A 1 991 ? 47.298 47.927 -34.392 1.00 55.56 ? 991 GLU A C 1 ATOM 7764 O O . GLU A 1 991 ? 47.107 47.018 -33.569 1.00 55.85 ? 991 GLU A O 1 ATOM 7765 C CB . GLU A 1 991 ? 45.414 49.343 -33.466 1.00 56.94 ? 991 GLU A CB 1 ATOM 7766 C CG . GLU A 1 991 ? 44.436 50.504 -33.691 1.00 59.02 ? 991 GLU A CG 1 ATOM 7767 C CD . GLU A 1 991 ? 43.216 50.453 -32.775 1.00 60.30 ? 991 GLU A CD 1 ATOM 7768 O OE1 . GLU A 1 991 ? 42.468 49.442 -32.829 1.00 61.20 ? 991 GLU A OE1 1 ATOM 7769 O OE2 . GLU A 1 991 ? 43.007 51.426 -32.012 1.00 59.87 ? 991 GLU A OE2 1 ATOM 7770 N N . GLU A 1 992 ? 48.458 48.091 -35.016 1.00 55.84 ? 992 GLU A N 1 ATOM 7771 C CA . GLU A 1 992 ? 49.533 47.131 -34.821 1.00 56.74 ? 992 GLU A CA 1 ATOM 7772 C C . GLU A 1 992 ? 50.827 47.656 -34.198 1.00 55.52 ? 992 GLU A C 1 ATOM 7773 O O . GLU A 1 992 ? 50.843 48.615 -33.423 1.00 54.86 ? 992 GLU A O 1 ATOM 7774 C CB . GLU A 1 992 ? 49.879 46.490 -36.175 1.00 58.61 ? 992 GLU A CB 1 ATOM 7775 C CG . GLU A 1 992 ? 48.681 46.069 -37.047 1.00 60.84 ? 992 GLU A CG 1 ATOM 7776 C CD . GLU A 1 992 ? 47.959 44.815 -36.540 1.00 62.07 ? 992 GLU A CD 1 ATOM 7777 O OE1 . GLU A 1 992 ? 48.643 43.829 -36.170 1.00 63.11 ? 992 GLU A OE1 1 ATOM 7778 O OE2 . GLU A 1 992 ? 46.706 44.802 -36.531 1.00 63.07 ? 992 GLU A OE2 1 ATOM 7779 N N . HIS A 1 993 ? 51.906 46.979 -34.585 1.00 54.27 ? 993 HIS A N 1 ATOM 7780 C CA . HIS A 1 993 ? 53.286 47.252 -34.183 1.00 52.69 ? 993 HIS A CA 1 ATOM 7781 C C . HIS A 1 993 ? 53.606 48.032 -32.914 1.00 50.26 ? 993 HIS A C 1 ATOM 7782 O O . HIS A 1 993 ? 53.822 49.254 -32.961 1.00 50.12 ? 993 HIS A O 1 ATOM 7783 C CB . HIS A 1 993 ? 54.069 47.891 -35.356 1.00 54.42 ? 993 HIS A CB 1 ATOM 7784 C CG . HIS A 1 993 ? 53.398 49.078 -35.985 1.00 56.03 ? 993 HIS A CG 1 ATOM 7785 N ND1 . HIS A 1 993 ? 52.335 48.963 -36.859 1.00 57.52 ? 993 HIS A ND1 1 ATOM 7786 C CD2 . HIS A 1 993 ? 53.666 50.404 -35.897 1.00 56.51 ? 993 HIS A CD2 1 ATOM 7787 C CE1 . HIS A 1 993 ? 51.980 50.166 -37.283 1.00 57.32 ? 993 HIS A CE1 1 ATOM 7788 N NE2 . HIS A 1 993 ? 52.773 51.058 -36.714 1.00 56.77 ? 993 HIS A NE2 1 ATOM 7789 N N . THR A 1 994 ? 53.651 47.327 -31.783 1.00 46.62 ? 994 THR A N 1 ATOM 7790 C CA . THR A 1 994 ? 54.025 47.973 -30.524 1.00 42.94 ? 994 THR A CA 1 ATOM 7791 C C . THR A 1 994 ? 55.035 47.086 -29.788 1.00 40.55 ? 994 THR A C 1 ATOM 7792 O O . THR A 1 994 ? 55.090 45.870 -29.988 1.00 40.35 ? 994 THR A O 1 ATOM 7793 C CB . THR A 1 994 ? 52.799 48.283 -29.600 1.00 42.62 ? 994 THR A CB 1 ATOM 7794 O OG1 . THR A 1 994 ? 52.108 47.071 -29.273 1.00 41.79 ? 994 THR A OG1 1 ATOM 7795 C CG2 . THR A 1 994 ? 51.843 49.232 -30.290 1.00 41.56 ? 994 THR A CG2 1 ATOM 7796 N N . GLN A 1 995 ? 55.846 47.712 -28.946 1.00 37.13 ? 995 GLN A N 1 ATOM 7797 C CA . GLN A 1 995 ? 56.855 46.991 -28.202 1.00 33.93 ? 995 GLN A CA 1 ATOM 7798 C C . GLN A 1 995 ? 56.434 46.662 -26.794 1.00 31.53 ? 995 GLN A C 1 ATOM 7799 O O . GLN A 1 995 ? 55.731 47.427 -26.125 1.00 29.63 ? 995 GLN A O 1 ATOM 7800 C CB . GLN A 1 995 ? 58.135 47.800 -28.095 1.00 34.79 ? 995 GLN A CB 1 ATOM 7801 C CG . GLN A 1 995 ? 58.721 48.225 -29.392 1.00 35.30 ? 995 GLN A CG 1 ATOM 7802 C CD . GLN A 1 995 ? 59.581 49.426 -29.184 1.00 36.59 ? 995 GLN A CD 1 ATOM 7803 O OE1 . GLN A 1 995 ? 59.120 50.567 -29.339 1.00 33.13 ? 995 GLN A OE1 1 ATOM 7804 N NE2 . GLN A 1 995 ? 60.844 49.188 -28.778 1.00 37.12 ? 995 GLN A NE2 1 ATOM 7805 N N . LYS A 1 996 ? 56.912 45.514 -26.349 1.00 28.00 ? 996 LYS A N 1 ATOM 7806 C CA . LYS A 1 996 ? 56.642 45.060 -25.014 1.00 27.22 ? 996 LYS A CA 1 ATOM 7807 C C . LYS A 1 996 ? 57.357 46.052 -24.085 1.00 23.95 ? 996 LYS A C 1 ATOM 7808 O O . LYS A 1 996 ? 58.505 46.438 -24.333 1.00 22.38 ? 996 LYS A O 1 ATOM 7809 C CB . LYS A 1 996 ? 57.200 43.638 -24.838 1.00 28.46 ? 996 LYS A CB 1 ATOM 7810 C CG . LYS A 1 996 ? 56.994 43.042 -23.470 1.00 30.86 ? 996 LYS A CG 1 ATOM 7811 C CD . LYS A 1 996 ? 57.173 41.509 -23.521 1.00 34.24 ? 996 LYS A CD 1 ATOM 7812 C CE . LYS A 1 996 ? 57.194 40.914 -22.132 1.00 35.71 ? 996 LYS A CE 1 ATOM 7813 N NZ . LYS A 1 996 ? 58.369 41.479 -21.400 1.00 37.49 ? 996 LYS A NZ 1 ATOM 7814 N N . LEU A 1 997 ? 56.659 46.486 -23.044 1.00 21.76 ? 997 LEU A N 1 ATOM 7815 C CA . LEU A 1 997 ? 57.249 47.398 -22.080 1.00 20.02 ? 997 LEU A CA 1 ATOM 7816 C C . LEU A 1 997 ? 57.655 46.628 -20.824 1.00 18.72 ? 997 LEU A C 1 ATOM 7817 O O . LEU A 1 997 ? 56.820 46.074 -20.121 1.00 18.38 ? 997 LEU A O 1 ATOM 7818 C CB . LEU A 1 997 ? 56.259 48.504 -21.712 1.00 20.24 ? 997 LEU A CB 1 ATOM 7819 C CG . LEU A 1 997 ? 56.753 49.460 -20.623 1.00 20.88 ? 997 LEU A CG 1 ATOM 7820 C CD1 . LEU A 1 997 ? 57.954 50.259 -21.116 1.00 20.15 ? 997 LEU A CD1 1 ATOM 7821 C CD2 . LEU A 1 997 ? 55.630 50.386 -20.234 1.00 20.23 ? 997 LEU A CD2 1 ATOM 7822 N N . ASP A 1 998 ? 58.946 46.588 -20.541 1.00 17.79 ? 998 ASP A N 1 ATOM 7823 C CA . ASP A 1 998 ? 59.418 45.909 -19.343 1.00 17.73 ? 998 ASP A CA 1 ATOM 7824 C C . ASP A 1 998 ? 59.983 47.025 -18.490 1.00 17.04 ? 998 ASP A C 1 ATOM 7825 O O . ASP A 1 998 ? 61.114 47.450 -18.691 1.00 18.13 ? 998 ASP A O 1 ATOM 7826 C CB . ASP A 1 998 ? 60.520 44.895 -19.685 1.00 18.12 ? 998 ASP A CB 1 ATOM 7827 C CG . ASP A 1 998 ? 61.153 44.299 -18.436 1.00 18.54 ? 998 ASP A CG 1 ATOM 7828 O OD1 . ASP A 1 998 ? 62.227 43.660 -18.561 1.00 17.49 ? 998 ASP A OD1 1 ATOM 7829 O OD2 . ASP A 1 998 ? 60.566 44.484 -17.338 1.00 14.94 ? 998 ASP A OD2 1 ATOM 7830 N N . VAL A 1 999 ? 59.198 47.527 -17.547 1.00 16.71 ? 999 VAL A N 1 ATOM 7831 C CA . VAL A 1 999 ? 59.691 48.623 -16.709 1.00 16.39 ? 999 VAL A CA 1 ATOM 7832 C C . VAL A 1 999 ? 60.920 48.262 -15.885 1.00 16.54 ? 999 VAL A C 1 ATOM 7833 O O . VAL A 1 999 ? 61.689 49.153 -15.502 1.00 15.63 ? 999 VAL A O 1 ATOM 7834 C CB . VAL A 1 999 ? 58.602 49.150 -15.754 1.00 14.62 ? 999 VAL A CB 1 ATOM 7835 C CG1 . VAL A 1 999 ? 57.459 49.670 -16.576 1.00 14.45 ? 999 VAL A CG1 1 ATOM 7836 C CG2 . VAL A 1 999 ? 58.144 48.049 -14.776 1.00 14.94 ? 999 VAL A CG2 1 ATOM 7837 N N . CYS A 1 1000 ? 61.112 46.973 -15.610 1.00 15.43 ? 1000 CYS A N 1 ATOM 7838 C CA . CYS A 1 1000 ? 62.274 46.585 -14.817 1.00 17.86 ? 1000 CYS A CA 1 ATOM 7839 C C . CYS A 1 1000 ? 63.596 46.835 -15.567 1.00 17.87 ? 1000 CYS A C 1 ATOM 7840 O O . CYS A 1 1000 ? 64.658 46.951 -14.947 1.00 17.86 ? 1000 CYS A O 1 ATOM 7841 C CB . CYS A 1 1000 ? 62.139 45.129 -14.314 1.00 20.75 ? 1000 CYS A CB 1 ATOM 7842 S SG . CYS A 1 1000 ? 61.345 45.105 -12.650 1.00 23.27 ? 1000 CYS A SG 1 ATOM 7843 N N . HIS A 1 1001 ? 63.530 46.957 -16.889 1.00 17.81 ? 1001 HIS A N 1 ATOM 7844 C CA . HIS A 1 1001 ? 64.742 47.273 -17.631 1.00 18.54 ? 1001 HIS A CA 1 ATOM 7845 C C . HIS A 1 1001 ? 64.818 48.726 -18.140 1.00 18.66 ? 1001 HIS A C 1 ATOM 7846 O O . HIS A 1 1001 ? 65.656 49.048 -18.986 1.00 20.44 ? 1001 HIS A O 1 ATOM 7847 C CB . HIS A 1 1001 ? 64.943 46.298 -18.784 1.00 19.02 ? 1001 HIS A CB 1 ATOM 7848 C CG . HIS A 1 1001 ? 65.453 44.965 -18.346 1.00 19.74 ? 1001 HIS A CG 1 ATOM 7849 N ND1 . HIS A 1 1001 ? 64.621 43.963 -17.902 1.00 19.51 ? 1001 HIS A ND1 1 ATOM 7850 C CD2 . HIS A 1 1001 ? 66.716 44.486 -18.225 1.00 20.26 ? 1001 HIS A CD2 1 ATOM 7851 C CE1 . HIS A 1 1001 ? 65.344 42.923 -17.524 1.00 19.99 ? 1001 HIS A CE1 1 ATOM 7852 N NE2 . HIS A 1 1001 ? 66.619 43.215 -17.707 1.00 20.49 ? 1001 HIS A NE2 1 ATOM 7853 N N . LEU A 1 1002 ? 63.967 49.619 -17.636 1.00 17.82 ? 1002 LEU A N 1 ATOM 7854 C CA . LEU A 1 1002 ? 64.040 51.019 -18.082 1.00 17.79 ? 1002 LEU A CA 1 ATOM 7855 C C . LEU A 1 1002 ? 65.331 51.659 -17.550 1.00 19.34 ? 1002 LEU A C 1 ATOM 7856 O O . LEU A 1 1002 ? 65.882 52.553 -18.180 1.00 20.51 ? 1002 LEU A O 1 ATOM 7857 C CB . LEU A 1 1002 ? 62.821 51.823 -17.612 1.00 18.19 ? 1002 LEU A CB 1 ATOM 7858 C CG . LEU A 1 1002 ? 61.547 51.615 -18.418 1.00 17.97 ? 1002 LEU A CG 1 ATOM 7859 C CD1 . LEU A 1 1002 ? 60.386 52.358 -17.777 1.00 17.55 ? 1002 LEU A CD1 1 ATOM 7860 C CD2 . LEU A 1 1002 ? 61.801 52.076 -19.856 1.00 17.31 ? 1002 LEU A CD2 1 ATOM 7861 N N . LEU A 1 1003 ? 65.804 51.223 -16.383 1.00 19.37 ? 1003 LEU A N 1 ATOM 7862 C CA . LEU A 1 1003 ? 67.057 51.737 -15.847 1.00 19.92 ? 1003 LEU A CA 1 ATOM 7863 C C . LEU A 1 1003 ? 68.105 50.626 -15.998 1.00 21.09 ? 1003 LEU A C 1 ATOM 7864 O O . LEU A 1 1003 ? 67.780 49.451 -15.944 1.00 19.99 ? 1003 LEU A O 1 ATOM 7865 C CB . LEU A 1 1003 ? 66.923 52.124 -14.382 1.00 22.22 ? 1003 LEU A CB 1 ATOM 7866 C CG . LEU A 1 1003 ? 66.470 53.569 -14.163 1.00 25.14 ? 1003 LEU A CG 1 ATOM 7867 C CD1 . LEU A 1 1003 ? 64.985 53.730 -14.410 1.00 25.68 ? 1003 LEU A CD1 1 ATOM 7868 C CD2 . LEU A 1 1003 ? 66.773 53.946 -12.750 1.00 27.87 ? 1003 LEU A CD2 1 ATOM 7869 N N . PRO A 1 1004 ? 69.379 50.992 -16.191 1.00 20.51 ? 1004 PRO A N 1 ATOM 7870 C CA . PRO A 1 1004 ? 70.407 49.965 -16.350 1.00 20.47 ? 1004 PRO A CA 1 ATOM 7871 C C . PRO A 1 1004 ? 70.859 49.289 -15.075 1.00 20.23 ? 1004 PRO A C 1 ATOM 7872 O O . PRO A 1 1004 ? 70.518 49.704 -13.957 1.00 18.28 ? 1004 PRO A O 1 ATOM 7873 C CB . PRO A 1 1004 ? 71.543 50.734 -17.016 1.00 20.75 ? 1004 PRO A CB 1 ATOM 7874 C CG . PRO A 1 1004 ? 71.463 52.053 -16.312 1.00 20.45 ? 1004 PRO A CG 1 ATOM 7875 C CD . PRO A 1 1004 ? 69.959 52.342 -16.344 1.00 21.30 ? 1004 PRO A CD 1 ATOM 7876 N N . ASN A 1 1005 ? 71.630 48.227 -15.270 1.00 19.85 ? 1005 ASN A N 1 ATOM 7877 C CA . ASN A 1 1005 ? 72.200 47.464 -14.181 1.00 21.11 ? 1005 ASN A CA 1 ATOM 7878 C C . ASN A 1 1005 ? 71.158 46.889 -13.247 1.00 20.67 ? 1005 ASN A C 1 ATOM 7879 O O . ASN A 1 1005 ? 71.345 46.889 -12.029 1.00 21.40 ? 1005 ASN A O 1 ATOM 7880 C CB . ASN A 1 1005 ? 73.156 48.340 -13.380 1.00 23.11 ? 1005 ASN A CB 1 ATOM 7881 C CG . ASN A 1 1005 ? 74.155 49.070 -14.259 1.00 26.51 ? 1005 ASN A CG 1 ATOM 7882 O OD1 . ASN A 1 1005 ? 74.911 48.450 -15.008 1.00 26.96 ? 1005 ASN A OD1 1 ATOM 7883 N ND2 . ASN A 1 1005 ? 74.163 50.403 -14.171 1.00 27.98 ? 1005 ASN A ND2 1 ATOM 7884 N N . VAL A 1 1006 ? 70.064 46.376 -13.796 1.00 21.01 ? 1006 VAL A N 1 ATOM 7885 C CA . VAL A 1 1006 ? 69.038 45.811 -12.930 1.00 20.34 ? 1006 VAL A CA 1 ATOM 7886 C C . VAL A 1 1006 ? 69.583 44.506 -12.334 1.00 20.16 ? 1006 VAL A C 1 ATOM 7887 O O . VAL A 1 1006 ? 70.160 43.695 -13.039 1.00 20.90 ? 1006 VAL A O 1 ATOM 7888 C CB . VAL A 1 1006 ? 67.714 45.565 -13.716 1.00 19.37 ? 1006 VAL A CB 1 ATOM 7889 C CG1 . VAL A 1 1006 ? 67.908 44.518 -14.758 1.00 19.02 ? 1006 VAL A CG1 1 ATOM 7890 C CG2 . VAL A 1 1006 ? 66.609 45.142 -12.772 1.00 18.71 ? 1006 VAL A CG2 1 ATOM 7891 N N . ALA A 1 1007 ? 69.391 44.315 -11.037 1.00 20.40 ? 1007 ALA A N 1 ATOM 7892 C CA . ALA A 1 1007 ? 69.859 43.124 -10.351 1.00 20.41 ? 1007 ALA A CA 1 ATOM 7893 C C . ALA A 1 1007 ? 68.671 42.318 -9.834 1.00 21.38 ? 1007 ALA A C 1 ATOM 7894 O O . ALA A 1 1007 ? 68.784 41.129 -9.559 1.00 20.99 ? 1007 ALA A O 1 ATOM 7895 C CB . ALA A 1 1007 ? 70.764 43.525 -9.189 1.00 20.86 ? 1007 ALA A CB 1 ATOM 7896 N N . ARG A 1 1008 ? 67.521 42.970 -9.700 1.00 20.90 ? 1008 ARG A N 1 ATOM 7897 C CA . ARG A 1 1008 ? 66.339 42.274 -9.220 1.00 20.26 ? 1008 ARG A CA 1 ATOM 7898 C C . ARG A 1 1008 ? 65.070 42.999 -9.652 1.00 20.15 ? 1008 ARG A C 1 ATOM 7899 O O . ARG A 1 1008 ? 65.070 44.230 -9.826 1.00 18.70 ? 1008 ARG A O 1 ATOM 7900 C CB . ARG A 1 1008 ? 66.396 42.195 -7.707 1.00 22.45 ? 1008 ARG A CB 1 ATOM 7901 C CG . ARG A 1 1008 ? 65.361 41.319 -7.089 1.00 26.71 ? 1008 ARG A CG 1 ATOM 7902 C CD . ARG A 1 1008 ? 65.434 41.438 -5.564 1.00 29.55 ? 1008 ARG A CD 1 ATOM 7903 N NE . ARG A 1 1008 ? 64.654 40.391 -4.910 1.00 34.27 ? 1008 ARG A NE 1 ATOM 7904 C CZ . ARG A 1 1008 ? 65.041 39.115 -4.784 1.00 37.13 ? 1008 ARG A CZ 1 ATOM 7905 N NH1 . ARG A 1 1008 ? 66.222 38.716 -5.267 1.00 37.36 ? 1008 ARG A NH1 1 ATOM 7906 N NH2 . ARG A 1 1008 ? 64.235 38.231 -4.187 1.00 36.67 ? 1008 ARG A NH2 1 ATOM 7907 N N . CYS A 1 1009 ? 64.003 42.226 -9.841 1.00 19.12 ? 1009 CYS A N 1 ATOM 7908 C CA . CYS A 1 1009 ? 62.710 42.759 -10.237 1.00 20.06 ? 1009 CYS A CA 1 ATOM 7909 C C . CYS A 1 1009 ? 61.635 42.055 -9.414 1.00 19.90 ? 1009 CYS A C 1 ATOM 7910 O O . CYS A 1 1009 ? 61.519 40.822 -9.454 1.00 18.79 ? 1009 CYS A O 1 ATOM 7911 C CB . CYS A 1 1009 ? 62.449 42.518 -11.727 1.00 21.68 ? 1009 CYS A CB 1 ATOM 7912 S SG . CYS A 1 1009 ? 60.865 43.182 -12.413 1.00 26.37 ? 1009 CYS A SG 1 ATOM 7913 N N . GLU A 1 1010 ? 60.854 42.842 -8.671 1.00 17.78 ? 1010 GLU A N 1 ATOM 7914 C CA . GLU A 1 1010 ? 59.781 42.300 -7.846 1.00 17.53 ? 1010 GLU A CA 1 ATOM 7915 C C . GLU A 1 1010 ? 58.418 42.932 -8.091 1.00 17.62 ? 1010 GLU A C 1 ATOM 7916 O O . GLU A 1 1010 ? 58.302 44.156 -8.328 1.00 16.21 ? 1010 GLU A O 1 ATOM 7917 C CB . GLU A 1 1010 ? 60.149 42.474 -6.365 1.00 19.19 ? 1010 GLU A CB 1 ATOM 7918 C CG . GLU A 1 1010 ? 61.383 41.658 -5.979 1.00 24.60 ? 1010 GLU A CG 1 ATOM 7919 C CD . GLU A 1 1010 ? 62.138 42.197 -4.776 1.00 28.11 ? 1010 GLU A CD 1 ATOM 7920 O OE1 . GLU A 1 1010 ? 62.548 43.400 -4.771 1.00 29.68 ? 1010 GLU A OE1 1 ATOM 7921 O OE2 . GLU A 1 1010 ? 62.339 41.386 -3.835 1.00 30.21 ? 1010 GLU A OE2 1 ATOM 7922 N N . ARG A 1 1011 ? 57.385 42.096 -8.057 1.00 16.56 ? 1011 ARG A N 1 ATOM 7923 C CA . ARG A 1 1011 ? 56.021 42.597 -8.137 1.00 15.74 ? 1011 ARG A CA 1 ATOM 7924 C C . ARG A 1 1011 ? 55.672 42.906 -6.672 1.00 14.79 ? 1011 ARG A C 1 ATOM 7925 O O . ARG A 1 1011 ? 56.003 42.128 -5.772 1.00 13.38 ? 1011 ARG A O 1 ATOM 7926 C CB . ARG A 1 1011 ? 55.071 41.545 -8.676 1.00 17.36 ? 1011 ARG A CB 1 ATOM 7927 C CG . ARG A 1 1011 ? 53.694 42.142 -8.938 1.00 21.95 ? 1011 ARG A CG 1 ATOM 7928 C CD . ARG A 1 1011 ? 52.896 41.207 -9.761 1.00 25.59 ? 1011 ARG A CD 1 ATOM 7929 N NE . ARG A 1 1011 ? 52.546 40.065 -8.950 1.00 30.42 ? 1011 ARG A NE 1 ATOM 7930 C CZ . ARG A 1 1011 ? 51.569 40.097 -8.051 1.00 32.63 ? 1011 ARG A CZ 1 ATOM 7931 N NH1 . ARG A 1 1011 ? 50.873 41.224 -7.886 1.00 35.71 ? 1011 ARG A NH1 1 ATOM 7932 N NH2 . ARG A 1 1011 ? 51.276 39.022 -7.330 1.00 33.82 ? 1011 ARG A NH2 1 ATOM 7933 N N . THR A 1 1012 ? 55.002 44.026 -6.435 1.00 13.13 ? 1012 THR A N 1 ATOM 7934 C CA . THR A 1 1012 ? 54.677 44.440 -5.073 1.00 11.89 ? 1012 THR A CA 1 ATOM 7935 C C . THR A 1 1012 ? 53.229 44.969 -4.971 1.00 11.97 ? 1012 THR A C 1 ATOM 7936 O O . THR A 1 1012 ? 52.514 45.131 -5.961 1.00 11.84 ? 1012 THR A O 1 ATOM 7937 C CB . THR A 1 1012 ? 55.584 45.639 -4.625 1.00 12.54 ? 1012 THR A CB 1 ATOM 7938 O OG1 . THR A 1 1012 ? 55.245 46.793 -5.418 1.00 11.70 ? 1012 THR A OG1 1 ATOM 7939 C CG2 . THR A 1 1012 ? 57.086 45.354 -4.840 1.00 10.91 ? 1012 THR A CG2 1 ATOM 7940 N N . THR A 1 1013 ? 52.809 45.240 -3.753 1.00 11.47 ? 1013 THR A N 1 ATOM 7941 C CA . THR A 1 1013 ? 51.532 45.846 -3.544 1.00 10.31 ? 1013 THR A CA 1 ATOM 7942 C C . THR A 1 1013 ? 51.643 47.244 -4.200 1.00 10.54 ? 1013 THR A C 1 ATOM 7943 O O . THR A 1 1013 ? 52.753 47.786 -4.378 1.00 9.47 ? 1013 THR A O 1 ATOM 7944 C CB . THR A 1 1013 ? 51.257 45.967 -2.037 1.00 10.85 ? 1013 THR A CB 1 ATOM 7945 O OG1 . THR A 1 1013 ? 52.471 46.361 -1.357 1.00 9.81 ? 1013 THR A OG1 1 ATOM 7946 C CG2 . THR A 1 1013 ? 50.756 44.621 -1.464 1.00 10.13 ? 1013 THR A CG2 1 ATOM 7947 N N . LEU A 1 1014 ? 50.501 47.853 -4.535 1.00 10.38 ? 1014 LEU A N 1 ATOM 7948 C CA . LEU A 1 1014 ? 50.507 49.160 -5.191 1.00 9.00 ? 1014 LEU A CA 1 ATOM 7949 C C . LEU A 1 1014 ? 51.196 50.268 -4.435 1.00 9.14 ? 1014 LEU A C 1 ATOM 7950 O O . LEU A 1 1014 ? 51.572 51.276 -5.034 1.00 9.82 ? 1014 LEU A O 1 ATOM 7951 C CB . LEU A 1 1014 ? 49.067 49.610 -5.551 1.00 7.43 ? 1014 LEU A CB 1 ATOM 7952 C CG . LEU A 1 1014 ? 48.276 48.617 -6.421 1.00 6.86 ? 1014 LEU A CG 1 ATOM 7953 C CD1 . LEU A 1 1014 ? 46.946 49.279 -6.868 1.00 6.01 ? 1014 LEU A CD1 1 ATOM 7954 C CD2 . LEU A 1 1014 ? 49.072 48.233 -7.618 1.00 8.48 ? 1014 LEU A CD2 1 ATOM 7955 N N . THR A 1 1015 ? 51.393 50.085 -3.132 1.00 9.74 ? 1015 THR A N 1 ATOM 7956 C CA . THR A 1 1015 ? 52.059 51.071 -2.283 1.00 8.29 ? 1015 THR A CA 1 ATOM 7957 C C . THR A 1 1015 ? 53.576 50.839 -2.217 1.00 9.62 ? 1015 THR A C 1 ATOM 7958 O O . THR A 1 1015 ? 54.283 51.590 -1.544 1.00 6.85 ? 1015 THR A O 1 ATOM 7959 C CB . THR A 1 1015 ? 51.543 50.957 -0.817 1.00 9.70 ? 1015 THR A CB 1 ATOM 7960 O OG1 . THR A 1 1015 ? 51.679 49.597 -0.387 1.00 9.30 ? 1015 THR A OG1 1 ATOM 7961 C CG2 . THR A 1 1015 ? 50.085 51.406 -0.682 1.00 8.22 ? 1015 THR A CG2 1 ATOM 7962 N N . PHE A 1 1016 ? 54.042 49.788 -2.907 1.00 9.10 ? 1016 PHE A N 1 ATOM 7963 C CA . PHE A 1 1016 ? 55.442 49.325 -2.924 1.00 9.85 ? 1016 PHE A CA 1 ATOM 7964 C C . PHE A 1 1016 ? 55.929 48.792 -1.574 1.00 10.48 ? 1016 PHE A C 1 ATOM 7965 O O . PHE A 1 1016 ? 57.123 48.503 -1.433 1.00 10.63 ? 1016 PHE A O 1 ATOM 7966 C CB . PHE A 1 1016 ? 56.416 50.437 -3.359 1.00 10.89 ? 1016 PHE A CB 1 ATOM 7967 C CG . PHE A 1 1016 ? 56.053 51.092 -4.657 1.00 9.57 ? 1016 PHE A CG 1 ATOM 7968 C CD1 . PHE A 1 1016 ? 55.862 52.469 -4.718 1.00 8.83 ? 1016 PHE A CD1 1 ATOM 7969 C CD2 . PHE A 1 1016 ? 55.902 50.326 -5.816 1.00 7.03 ? 1016 PHE A CD2 1 ATOM 7970 C CE1 . PHE A 1 1016 ? 55.525 53.085 -5.920 1.00 8.66 ? 1016 PHE A CE1 1 ATOM 7971 C CE2 . PHE A 1 1016 ? 55.565 50.920 -7.034 1.00 7.55 ? 1016 PHE A CE2 1 ATOM 7972 C CZ . PHE A 1 1016 ? 55.377 52.299 -7.088 1.00 10.04 ? 1016 PHE A CZ 1 ATOM 7973 N N . LEU A 1 1017 ? 55.029 48.624 -0.600 1.00 11.15 ? 1017 LEU A N 1 ATOM 7974 C CA . LEU A 1 1017 ? 55.443 48.201 0.748 1.00 10.68 ? 1017 LEU A CA 1 ATOM 7975 C C . LEU A 1 1017 ? 55.606 46.718 0.974 1.00 12.62 ? 1017 LEU A C 1 ATOM 7976 O O . LEU A 1 1017 ? 56.227 46.313 1.948 1.00 13.11 ? 1017 LEU A O 1 ATOM 7977 C CB . LEU A 1 1017 ? 54.492 48.801 1.822 1.00 9.54 ? 1017 LEU A CB 1 ATOM 7978 C CG . LEU A 1 1017 ? 54.415 50.353 1.774 1.00 8.32 ? 1017 LEU A CG 1 ATOM 7979 C CD1 . LEU A 1 1017 ? 53.377 50.900 2.744 1.00 7.78 ? 1017 LEU A CD1 1 ATOM 7980 C CD2 . LEU A 1 1017 ? 55.784 50.918 2.130 1.00 7.62 ? 1017 LEU A CD2 1 ATOM 7981 N N . GLN A 1 1018 ? 55.080 45.885 0.096 1.00 12.84 ? 1018 GLN A N 1 ATOM 7982 C CA . GLN A 1 1018 ? 55.260 44.462 0.309 1.00 15.26 ? 1018 GLN A CA 1 ATOM 7983 C C . GLN A 1 1018 ? 55.609 43.735 -0.996 1.00 15.43 ? 1018 GLN A C 1 ATOM 7984 O O . GLN A 1 1018 ? 54.909 43.889 -1.989 1.00 14.71 ? 1018 GLN A O 1 ATOM 7985 C CB . GLN A 1 1018 ? 53.993 43.833 0.908 1.00 18.13 ? 1018 GLN A CB 1 ATOM 7986 C CG . GLN A 1 1018 ? 54.184 42.331 1.169 1.00 20.73 ? 1018 GLN A CG 1 ATOM 7987 C CD . GLN A 1 1018 ? 52.897 41.588 1.492 1.00 24.23 ? 1018 GLN A CD 1 ATOM 7988 O OE1 . GLN A 1 1018 ? 51.799 42.170 1.503 1.00 25.47 ? 1018 GLN A OE1 1 ATOM 7989 N NE2 . GLN A 1 1018 ? 53.023 40.276 1.739 1.00 24.54 ? 1018 GLN A NE2 1 ATOM 7990 N N . ASN A 1 1019 ? 56.690 42.950 -0.983 1.00 15.41 ? 1019 ASN A N 1 ATOM 7991 C CA . ASN A 1 1019 ? 57.098 42.177 -2.151 1.00 17.40 ? 1019 ASN A CA 1 ATOM 7992 C C . ASN A 1 1019 ? 56.164 40.979 -2.249 1.00 18.56 ? 1019 ASN A C 1 ATOM 7993 O O . ASN A 1 1019 ? 55.974 40.244 -1.284 1.00 20.42 ? 1019 ASN A O 1 ATOM 7994 C CB . ASN A 1 1019 ? 58.552 41.701 -2.022 1.00 17.50 ? 1019 ASN A CB 1 ATOM 7995 C CG . ASN A 1 1019 ? 59.538 42.866 -1.960 1.00 19.59 ? 1019 ASN A CG 1 ATOM 7996 O OD1 . ASN A 1 1019 ? 59.305 43.919 -2.573 1.00 20.69 ? 1019 ASN A OD1 1 ATOM 7997 N ND2 . ASN A 1 1019 ? 60.640 42.686 -1.232 1.00 20.26 ? 1019 ASN A ND2 1 ATOM 7998 N N . LEU A 1 1020 ? 55.586 40.781 -3.418 1.00 19.13 ? 1020 LEU A N 1 ATOM 7999 C CA . LEU A 1 1020 ? 54.642 39.706 -3.597 1.00 18.88 ? 1020 LEU A CA 1 ATOM 8000 C C . LEU A 1 1020 ? 55.204 38.659 -4.529 1.00 19.52 ? 1020 LEU A C 1 ATOM 8001 O O . LEU A 1 1020 ? 54.819 37.493 -4.473 1.00 18.03 ? 1020 LEU A O 1 ATOM 8002 C CB . LEU A 1 1020 ? 53.332 40.247 -4.199 1.00 18.15 ? 1020 LEU A CB 1 ATOM 8003 C CG . LEU A 1 1020 ? 52.526 41.341 -3.478 1.00 19.27 ? 1020 LEU A CG 1 ATOM 8004 C CD1 . LEU A 1 1020 ? 51.430 41.878 -4.411 1.00 18.59 ? 1020 LEU A CD1 1 ATOM 8005 C CD2 . LEU A 1 1020 ? 51.912 40.789 -2.219 1.00 18.12 ? 1020 LEU A CD2 1 ATOM 8006 N N . GLU A 1 1021 ? 56.109 39.068 -5.402 1.00 21.20 ? 1021 GLU A N 1 ATOM 8007 C CA . GLU A 1 1021 ? 56.662 38.117 -6.367 1.00 23.48 ? 1021 GLU A CA 1 ATOM 8008 C C . GLU A 1 1021 ? 58.063 38.470 -6.857 1.00 23.92 ? 1021 GLU A C 1 ATOM 8009 O O . GLU A 1 1021 ? 58.353 39.617 -7.208 1.00 23.19 ? 1021 GLU A O 1 ATOM 8010 C CB . GLU A 1 1021 ? 55.701 38.009 -7.548 1.00 24.13 ? 1021 GLU A CB 1 ATOM 8011 C CG . GLU A 1 1021 ? 56.103 36.959 -8.541 1.00 30.15 ? 1021 GLU A CG 1 ATOM 8012 C CD . GLU A 1 1021 ? 55.079 36.760 -9.633 1.00 31.56 ? 1021 GLU A CD 1 ATOM 8013 O OE1 . GLU A 1 1021 ? 55.328 35.874 -10.482 1.00 34.19 ? 1021 GLU A OE1 1 ATOM 8014 O OE2 . GLU A 1 1021 ? 54.045 37.479 -9.641 1.00 31.73 ? 1021 GLU A OE2 1 ATOM 8015 N N . HIS A 1 1022 ? 58.936 37.476 -6.853 1.00 25.09 ? 1022 HIS A N 1 ATOM 8016 C CA . HIS A 1 1022 ? 60.314 37.636 -7.300 1.00 26.69 ? 1022 HIS A CA 1 ATOM 8017 C C . HIS A 1 1022 ? 60.290 37.227 -8.770 1.00 26.68 ? 1022 HIS A C 1 ATOM 8018 O O . HIS A 1 1022 ? 59.993 36.082 -9.101 1.00 26.88 ? 1022 HIS A O 1 ATOM 8019 C CB . HIS A 1 1022 ? 61.219 36.727 -6.474 1.00 29.74 ? 1022 HIS A CB 1 ATOM 8020 C CG . HIS A 1 1022 ? 62.634 36.720 -6.937 1.00 33.40 ? 1022 HIS A CG 1 ATOM 8021 N ND1 . HIS A 1 1022 ? 63.454 37.825 -6.830 1.00 35.59 ? 1022 HIS A ND1 1 ATOM 8022 C CD2 . HIS A 1 1022 ? 63.351 35.777 -7.595 1.00 34.63 ? 1022 HIS A CD2 1 ATOM 8023 C CE1 . HIS A 1 1022 ? 64.614 37.562 -7.408 1.00 36.57 ? 1022 HIS A CE1 1 ATOM 8024 N NE2 . HIS A 1 1022 ? 64.577 36.328 -7.881 1.00 36.17 ? 1022 HIS A NE2 1 ATOM 8025 N N . LEU A 1 1023 ? 60.615 38.160 -9.657 1.00 26.38 ? 1023 LEU A N 1 ATOM 8026 C CA . LEU A 1 1023 ? 60.497 37.897 -11.080 1.00 25.92 ? 1023 LEU A CA 1 ATOM 8027 C C . LEU A 1 1023 ? 61.666 37.323 -11.860 1.00 27.07 ? 1023 LEU A C 1 ATOM 8028 O O . LEU A 1 1023 ? 62.785 37.856 -11.860 1.00 25.11 ? 1023 LEU A O 1 ATOM 8029 C CB . LEU A 1 1023 ? 60.013 39.169 -11.778 1.00 24.21 ? 1023 LEU A CB 1 ATOM 8030 C CG . LEU A 1 1023 ? 58.727 39.733 -11.183 1.00 23.18 ? 1023 LEU A CG 1 ATOM 8031 C CD1 . LEU A 1 1023 ? 58.614 41.176 -11.528 1.00 24.22 ? 1023 LEU A CD1 1 ATOM 8032 C CD2 . LEU A 1 1023 ? 57.518 38.933 -11.693 1.00 24.12 ? 1023 LEU A CD2 1 ATOM 8033 N N . ASP A 1 1024 ? 61.354 36.239 -12.566 1.00 29.09 ? 1024 ASP A N 1 ATOM 8034 C CA . ASP A 1 1024 ? 62.314 35.534 -13.402 1.00 30.43 ? 1024 ASP A CA 1 ATOM 8035 C C . ASP A 1 1024 ? 62.840 36.412 -14.513 1.00 30.02 ? 1024 ASP A C 1 ATOM 8036 O O . ASP A 1 1024 ? 62.082 37.167 -15.155 1.00 30.15 ? 1024 ASP A O 1 ATOM 8037 C CB . ASP A 1 1024 ? 61.659 34.316 -14.028 1.00 33.77 ? 1024 ASP A CB 1 ATOM 8038 C CG . ASP A 1 1024 ? 61.389 33.234 -13.022 1.00 38.47 ? 1024 ASP A CG 1 ATOM 8039 O OD1 . ASP A 1 1024 ? 60.537 32.353 -13.329 1.00 40.18 ? 1024 ASP A OD1 1 ATOM 8040 O OD2 . ASP A 1 1024 ? 62.036 33.268 -11.929 1.00 41.23 ? 1024 ASP A OD2 1 ATOM 8041 N N . GLY A 1 1025 ? 64.137 36.296 -14.750 1.00 29.14 ? 1025 GLY A N 1 ATOM 8042 C CA . GLY A 1 1025 ? 64.763 37.064 -15.806 1.00 28.40 ? 1025 GLY A CA 1 ATOM 8043 C C . GLY A 1 1025 ? 64.694 38.544 -15.524 1.00 28.16 ? 1025 GLY A C 1 ATOM 8044 O O . GLY A 1 1025 ? 65.071 39.345 -16.364 1.00 28.87 ? 1025 GLY A O 1 ATOM 8045 N N . MET A 1 1026 ? 64.240 38.896 -14.325 1.00 27.50 ? 1026 MET A N 1 ATOM 8046 C CA . MET A 1 1026 ? 64.093 40.287 -13.915 1.00 27.39 ? 1026 MET A CA 1 ATOM 8047 C C . MET A 1 1026 ? 63.226 41.010 -14.928 1.00 26.63 ? 1026 MET A C 1 ATOM 8048 O O . MET A 1 1026 ? 63.472 42.158 -15.273 1.00 25.24 ? 1026 MET A O 1 ATOM 8049 C CB . MET A 1 1026 ? 65.450 40.967 -13.815 1.00 28.91 ? 1026 MET A CB 1 ATOM 8050 C CG . MET A 1 1026 ? 66.436 40.170 -12.973 1.00 32.19 ? 1026 MET A CG 1 ATOM 8051 S SD . MET A 1 1026 ? 68.041 40.949 -12.839 1.00 35.02 ? 1026 MET A SD 1 ATOM 8052 C CE . MET A 1 1026 ? 68.713 40.611 -14.488 1.00 34.48 ? 1026 MET A CE 1 ATOM 8053 N N . VAL A 1 1027 ? 62.192 40.328 -15.390 1.00 25.50 ? 1027 VAL A N 1 ATOM 8054 C CA . VAL A 1 1027 ? 61.308 40.918 -16.368 1.00 26.60 ? 1027 VAL A CA 1 ATOM 8055 C C . VAL A 1 1027 ? 59.921 41.152 -15.802 1.00 27.24 ? 1027 VAL A C 1 ATOM 8056 O O . VAL A 1 1027 ? 59.261 40.224 -15.347 1.00 27.56 ? 1027 VAL A O 1 ATOM 8057 C CB . VAL A 1 1027 ? 61.212 40.034 -17.628 1.00 25.56 ? 1027 VAL A CB 1 ATOM 8058 C CG1 . VAL A 1 1027 ? 60.110 40.549 -18.549 1.00 26.57 ? 1027 VAL A CG1 1 ATOM 8059 C CG2 . VAL A 1 1027 ? 62.577 40.045 -18.370 1.00 24.85 ? 1027 VAL A CG2 1 ATOM 8060 N N . ALA A 1 1028 ? 59.484 42.404 -15.832 1.00 27.35 ? 1028 ALA A N 1 ATOM 8061 C CA . ALA A 1 1028 ? 58.160 42.756 -15.331 1.00 28.44 ? 1028 ALA A CA 1 ATOM 8062 C C . ALA A 1 1028 ? 57.172 42.559 -16.455 1.00 29.05 ? 1028 ALA A C 1 ATOM 8063 O O . ALA A 1 1028 ? 57.141 43.346 -17.404 1.00 31.43 ? 1028 ALA A O 1 ATOM 8064 C CB . ALA A 1 1028 ? 58.123 44.207 -14.877 1.00 27.86 ? 1028 ALA A CB 1 ATOM 8065 N N . PRO A 1 1029 ? 56.346 41.517 -16.371 1.00 28.63 ? 1029 PRO A N 1 ATOM 8066 C CA . PRO A 1 1029 ? 55.357 41.276 -17.436 1.00 28.80 ? 1029 PRO A CA 1 ATOM 8067 C C . PRO A 1 1029 ? 54.268 42.375 -17.469 1.00 28.38 ? 1029 PRO A C 1 ATOM 8068 O O . PRO A 1 1029 ? 54.058 43.059 -16.473 1.00 29.29 ? 1029 PRO A O 1 ATOM 8069 C CB . PRO A 1 1029 ? 54.786 39.911 -17.071 1.00 28.68 ? 1029 PRO A CB 1 ATOM 8070 C CG . PRO A 1 1029 ? 54.927 39.853 -15.561 1.00 29.19 ? 1029 PRO A CG 1 ATOM 8071 C CD . PRO A 1 1029 ? 56.207 40.576 -15.243 1.00 28.08 ? 1029 PRO A CD 1 ATOM 8072 N N . GLU A 1 1030 ? 53.599 42.570 -18.605 1.00 27.66 ? 1030 GLU A N 1 ATOM 8073 C CA . GLU A 1 1030 ? 52.551 43.588 -18.673 1.00 26.48 ? 1030 GLU A CA 1 ATOM 8074 C C . GLU A 1 1030 ? 51.281 43.019 -18.036 1.00 25.51 ? 1030 GLU A C 1 ATOM 8075 O O . GLU A 1 1030 ? 51.107 41.792 -17.899 1.00 26.29 ? 1030 GLU A O 1 ATOM 8076 C CB . GLU A 1 1030 ? 52.284 44.039 -20.129 1.00 27.53 ? 1030 GLU A CB 1 ATOM 8077 C CG . GLU A 1 1030 ? 53.546 44.568 -20.871 1.00 27.83 ? 1030 GLU A CG 1 ATOM 8078 C CD . GLU A 1 1030 ? 53.245 45.085 -22.288 1.00 28.38 ? 1030 GLU A CD 1 ATOM 8079 O OE1 . GLU A 1 1030 ? 52.282 44.574 -22.899 1.00 28.94 ? 1030 GLU A OE1 1 ATOM 8080 O OE2 . GLU A 1 1030 ? 53.964 45.984 -22.793 1.00 25.16 ? 1030 GLU A OE2 1 ATOM 8081 N N . VAL A 1 1031 ? 50.400 43.919 -17.629 1.00 23.25 ? 1031 VAL A N 1 ATOM 8082 C CA . VAL A 1 1031 ? 49.176 43.536 -16.967 1.00 20.64 ? 1031 VAL A CA 1 ATOM 8083 C C . VAL A 1 1031 ? 48.013 43.335 -17.928 1.00 18.58 ? 1031 VAL A C 1 ATOM 8084 O O . VAL A 1 1031 ? 48.072 43.727 -19.087 1.00 18.72 ? 1031 VAL A O 1 ATOM 8085 C CB . VAL A 1 1031 ? 48.815 44.604 -15.904 1.00 20.74 ? 1031 VAL A CB 1 ATOM 8086 C CG1 . VAL A 1 1031 ? 50.021 44.814 -14.987 1.00 22.35 ? 1031 VAL A CG1 1 ATOM 8087 C CG2 . VAL A 1 1031 ? 48.459 45.896 -16.560 1.00 19.70 ? 1031 VAL A CG2 1 ATOM 8088 N N . CYS A 1 1032 ? 46.960 42.720 -17.417 1.00 16.47 ? 1032 CYS A N 1 ATOM 8089 C CA . CYS A 1 1032 ? 45.747 42.429 -18.166 1.00 15.77 ? 1032 CYS A CA 1 ATOM 8090 C C . CYS A 1 1032 ? 44.832 43.651 -18.226 1.00 12.80 ? 1032 CYS A C 1 ATOM 8091 O O . CYS A 1 1032 ? 44.940 44.531 -17.397 1.00 13.17 ? 1032 CYS A O 1 ATOM 8092 C CB . CYS A 1 1032 ? 44.976 41.301 -17.466 1.00 16.01 ? 1032 CYS A CB 1 ATOM 8093 S SG . CYS A 1 1032 ? 45.780 39.661 -17.547 1.00 19.08 ? 1032 CYS A SG 1 ATOM 8094 N N . PRO A 1 1033 ? 43.874 43.669 -19.182 1.00 12.48 ? 1033 PRO A N 1 ATOM 8095 C CA . PRO A 1 1033 ? 42.937 44.779 -19.316 1.00 11.63 ? 1033 PRO A CA 1 ATOM 8096 C C . PRO A 1 1033 ? 42.206 44.982 -17.974 1.00 10.69 ? 1033 PRO A C 1 ATOM 8097 O O . PRO A 1 1033 ? 41.718 44.022 -17.368 1.00 9.05 ? 1033 PRO A O 1 ATOM 8098 C CB . PRO A 1 1033 ? 41.976 44.289 -20.408 1.00 12.08 ? 1033 PRO A CB 1 ATOM 8099 C CG . PRO A 1 1033 ? 42.826 43.384 -21.262 1.00 12.05 ? 1033 PRO A CG 1 ATOM 8100 C CD . PRO A 1 1033 ? 43.597 42.630 -20.200 1.00 12.91 ? 1033 PRO A CD 1 ATOM 8101 N N . MET A 1 1034 ? 42.136 46.239 -17.562 1.00 11.15 ? 1034 MET A N 1 ATOM 8102 C CA . MET A 1 1034 ? 41.510 46.709 -16.337 1.00 12.64 ? 1034 MET A CA 1 ATOM 8103 C C . MET A 1 1034 ? 42.282 46.360 -15.070 1.00 13.71 ? 1034 MET A C 1 ATOM 8104 O O . MET A 1 1034 ? 41.779 46.574 -13.966 1.00 14.64 ? 1034 MET A O 1 ATOM 8105 C CB . MET A 1 1034 ? 40.079 46.215 -16.197 1.00 11.84 ? 1034 MET A CB 1 ATOM 8106 C CG . MET A 1 1034 ? 39.146 46.718 -17.298 1.00 13.36 ? 1034 MET A CG 1 ATOM 8107 S SD . MET A 1 1034 ? 39.209 48.504 -17.387 1.00 12.10 ? 1034 MET A SD 1 ATOM 8108 C CE . MET A 1 1034 ? 38.300 48.989 -15.887 1.00 13.21 ? 1034 MET A CE 1 ATOM 8109 N N . GLU A 1 1035 ? 43.491 45.840 -15.221 1.00 13.16 ? 1035 GLU A N 1 ATOM 8110 C CA . GLU A 1 1035 ? 44.291 45.511 -14.048 1.00 13.70 ? 1035 GLU A CA 1 ATOM 8111 C C . GLU A 1 1035 ? 45.386 46.538 -13.825 1.00 12.84 ? 1035 GLU A C 1 ATOM 8112 O O . GLU A 1 1035 ? 45.765 47.260 -14.747 1.00 11.69 ? 1035 GLU A O 1 ATOM 8113 C CB . GLU A 1 1035 ? 44.898 44.111 -14.186 1.00 16.71 ? 1035 GLU A CB 1 ATOM 8114 C CG . GLU A 1 1035 ? 43.820 43.019 -14.059 1.00 23.26 ? 1035 GLU A CG 1 ATOM 8115 C CD . GLU A 1 1035 ? 43.287 42.840 -12.605 1.00 27.09 ? 1035 GLU A CD 1 ATOM 8116 O OE1 . GLU A 1 1035 ? 43.134 43.839 -11.864 1.00 27.70 ? 1035 GLU A OE1 1 ATOM 8117 O OE2 . GLU A 1 1035 ? 43.000 41.688 -12.216 1.00 30.49 ? 1035 GLU A OE2 1 ATOM 8118 N N . THR A 1 1036 ? 45.890 46.579 -12.591 1.00 12.33 ? 1036 THR A N 1 ATOM 8119 C CA . THR A 1 1036 ? 46.944 47.493 -12.181 1.00 11.09 ? 1036 THR A CA 1 ATOM 8120 C C . THR A 1 1036 ? 47.920 46.699 -11.328 1.00 11.71 ? 1036 THR A C 1 ATOM 8121 O O . THR A 1 1036 ? 47.514 45.953 -10.438 1.00 11.19 ? 1036 THR A O 1 ATOM 8122 C CB . THR A 1 1036 ? 46.400 48.636 -11.310 1.00 10.30 ? 1036 THR A CB 1 ATOM 8123 O OG1 . THR A 1 1036 ? 45.275 49.239 -11.966 1.00 7.69 ? 1036 THR A OG1 1 ATOM 8124 C CG2 . THR A 1 1036 ? 47.490 49.675 -11.083 1.00 8.48 ? 1036 THR A CG2 1 ATOM 8125 N N . ALA A 1 1037 ? 49.207 46.853 -11.611 1.00 11.66 ? 1037 ALA A N 1 ATOM 8126 C CA . ALA A 1 1037 ? 50.240 46.139 -10.874 1.00 11.31 ? 1037 ALA A CA 1 ATOM 8127 C C . ALA A 1 1037 ? 51.371 47.104 -10.567 1.00 11.62 ? 1037 ALA A C 1 ATOM 8128 O O . ALA A 1 1037 ? 51.478 48.173 -11.191 1.00 12.44 ? 1037 ALA A O 1 ATOM 8129 C CB . ALA A 1 1037 ? 50.764 44.954 -11.708 1.00 13.12 ? 1037 ALA A CB 1 ATOM 8130 N N . ALA A 1 1038 ? 52.185 46.747 -9.576 1.00 9.53 ? 1038 ALA A N 1 ATOM 8131 C CA . ALA A 1 1038 ? 53.312 47.570 -9.192 1.00 10.45 ? 1038 ALA A CA 1 ATOM 8132 C C . ALA A 1 1038 ? 54.554 46.687 -9.228 1.00 11.18 ? 1038 ALA A C 1 ATOM 8133 O O . ALA A 1 1038 ? 54.512 45.489 -8.888 1.00 10.87 ? 1038 ALA A O 1 ATOM 8134 C CB . ALA A 1 1038 ? 53.114 48.173 -7.792 1.00 7.57 ? 1038 ALA A CB 1 ATOM 8135 N N . TYR A 1 1039 ? 55.645 47.270 -9.711 1.00 11.69 ? 1039 TYR A N 1 ATOM 8136 C CA . TYR A 1 1039 ? 56.903 46.558 -9.773 1.00 11.36 ? 1039 TYR A CA 1 ATOM 8137 C C . TYR A 1 1039 ? 57.989 47.464 -9.222 1.00 12.38 ? 1039 TYR A C 1 ATOM 8138 O O . TYR A 1 1039 ? 57.907 48.697 -9.349 1.00 11.29 ? 1039 TYR A O 1 ATOM 8139 C CB . TYR A 1 1039 ? 57.245 46.183 -11.217 1.00 10.86 ? 1039 TYR A CB 1 ATOM 8140 C CG . TYR A 1 1039 ? 56.204 45.321 -11.897 1.00 12.91 ? 1039 TYR A CG 1 ATOM 8141 C CD1 . TYR A 1 1039 ? 55.260 45.886 -12.775 1.00 14.09 ? 1039 TYR A CD1 1 ATOM 8142 C CD2 . TYR A 1 1039 ? 56.182 43.935 -11.701 1.00 14.22 ? 1039 TYR A CD2 1 ATOM 8143 C CE1 . TYR A 1 1039 ? 54.325 45.075 -13.457 1.00 16.73 ? 1039 TYR A CE1 1 ATOM 8144 C CE2 . TYR A 1 1039 ? 55.264 43.132 -12.359 1.00 14.95 ? 1039 TYR A CE2 1 ATOM 8145 C CZ . TYR A 1 1039 ? 54.348 43.703 -13.238 1.00 16.78 ? 1039 TYR A CZ 1 ATOM 8146 O OH . TYR A 1 1039 ? 53.498 42.896 -13.947 1.00 19.26 ? 1039 TYR A OH 1 ATOM 8147 N N . VAL A 1 1040 ? 59.011 46.852 -8.627 1.00 12.56 ? 1040 VAL A N 1 ATOM 8148 C CA . VAL A 1 1040 ? 60.144 47.588 -8.105 1.00 12.39 ? 1040 VAL A CA 1 ATOM 8149 C C . VAL A 1 1040 ? 61.389 46.932 -8.687 1.00 14.98 ? 1040 VAL A C 1 ATOM 8150 O O . VAL A 1 1040 ? 61.568 45.699 -8.581 1.00 14.42 ? 1040 VAL A O 1 ATOM 8151 C CB . VAL A 1 1040 ? 60.223 47.540 -6.568 1.00 13.18 ? 1040 VAL A CB 1 ATOM 8152 C CG1 . VAL A 1 1040 ? 61.539 48.221 -6.081 1.00 11.96 ? 1040 VAL A CG1 1 ATOM 8153 C CG2 . VAL A 1 1040 ? 59.002 48.271 -5.963 1.00 11.48 ? 1040 VAL A CG2 1 ATOM 8154 N N . SER A 1 1041 ? 62.229 47.736 -9.338 1.00 14.18 ? 1041 SER A N 1 ATOM 8155 C CA . SER A 1 1041 ? 63.482 47.206 -9.877 1.00 15.50 ? 1041 SER A CA 1 ATOM 8156 C C . SER A 1 1041 ? 64.609 47.694 -8.951 1.00 14.38 ? 1041 SER A C 1 ATOM 8157 O O . SER A 1 1041 ? 64.576 48.820 -8.448 1.00 14.26 ? 1041 SER A O 1 ATOM 8158 C CB . SER A 1 1041 ? 63.710 47.680 -11.326 1.00 15.15 ? 1041 SER A CB 1 ATOM 8159 O OG . SER A 1 1041 ? 63.708 49.101 -11.453 1.00 15.53 ? 1041 SER A OG 1 ATOM 8160 N N . SER A 1 1042 ? 65.580 46.826 -8.699 1.00 14.21 ? 1042 SER A N 1 ATOM 8161 C CA . SER A 1 1042 ? 66.742 47.127 -7.835 1.00 14.46 ? 1042 SER A CA 1 ATOM 8162 C C . SER A 1 1042 ? 67.932 47.164 -8.775 1.00 14.77 ? 1042 SER A C 1 ATOM 8163 O O . SER A 1 1042 ? 68.038 46.340 -9.691 1.00 15.44 ? 1042 SER A O 1 ATOM 8164 C CB . SER A 1 1042 ? 66.929 46.031 -6.778 1.00 13.94 ? 1042 SER A CB 1 ATOM 8165 O OG . SER A 1 1042 ? 65.747 45.915 -5.994 1.00 15.81 ? 1042 SER A OG 1 ATOM 8166 N N . HIS A 1 1043 ? 68.807 48.133 -8.563 1.00 16.04 ? 1043 HIS A N 1 ATOM 8167 C CA . HIS A 1 1043 ? 69.957 48.338 -9.432 1.00 18.66 ? 1043 HIS A CA 1 ATOM 8168 C C . HIS A 1 1043 ? 71.208 48.459 -8.597 1.00 20.45 ? 1043 HIS A C 1 ATOM 8169 O O . HIS A 1 1043 ? 71.223 49.075 -7.527 1.00 19.81 ? 1043 HIS A O 1 ATOM 8170 C CB . HIS A 1 1043 ? 69.752 49.613 -10.260 1.00 17.53 ? 1043 HIS A CB 1 ATOM 8171 C CG . HIS A 1 1043 ? 68.475 49.601 -11.036 1.00 16.52 ? 1043 HIS A CG 1 ATOM 8172 N ND1 . HIS A 1 1043 ? 68.399 49.132 -12.332 1.00 15.97 ? 1043 HIS A ND1 1 ATOM 8173 C CD2 . HIS A 1 1043 ? 67.205 49.874 -10.658 1.00 15.69 ? 1043 HIS A CD2 1 ATOM 8174 C CE1 . HIS A 1 1043 ? 67.138 49.114 -12.717 1.00 16.26 ? 1043 HIS A CE1 1 ATOM 8175 N NE2 . HIS A 1 1043 ? 66.392 49.557 -11.720 1.00 16.63 ? 1043 HIS A NE2 1 ATOM 8176 N N . SER A 1 1044 ? 72.267 47.863 -9.103 1.00 23.41 ? 1044 SER A N 1 ATOM 8177 C CA . SER A 1 1044 ? 73.509 47.889 -8.375 1.00 27.45 ? 1044 SER A CA 1 ATOM 8178 C C . SER A 1 1044 ? 74.434 48.950 -8.931 1.00 29.01 ? 1044 SER A C 1 ATOM 8179 O O . SER A 1 1044 ? 75.639 48.657 -8.913 1.00 31.58 ? 1044 SER A O 1 ATOM 8180 C CB . SER A 1 1044 ? 74.159 46.508 -8.483 1.00 27.48 ? 1044 SER A CB 1 ATOM 8181 O OG . SER A 1 1044 ? 74.058 46.017 -9.827 1.00 28.44 ? 1044 SER A OG 1 HETATM 8182 C C1 . NAG B 2 . ? 57.962 45.091 13.631 1.00 39.77 ? 2001 NAG A C1 1 HETATM 8183 C C2 . NAG B 2 . ? 59.451 44.985 13.967 1.00 42.68 ? 2001 NAG A C2 1 HETATM 8184 C C3 . NAG B 2 . ? 59.958 43.547 13.805 1.00 43.53 ? 2001 NAG A C3 1 HETATM 8185 C C4 . NAG B 2 . ? 58.801 42.559 13.780 1.00 42.78 ? 2001 NAG A C4 1 HETATM 8186 C C5 . NAG B 2 . ? 57.794 42.898 12.662 1.00 43.57 ? 2001 NAG A C5 1 HETATM 8187 C C6 . NAG B 2 . ? 56.423 42.340 12.980 1.00 43.95 ? 2001 NAG A C6 1 HETATM 8188 C C7 . NAG B 2 . ? 61.373 46.304 13.357 1.00 47.69 ? 2001 NAG A C7 1 HETATM 8189 C C8 . NAG B 2 . ? 61.513 47.130 14.635 1.00 47.59 ? 2001 NAG A C8 1 HETATM 8190 N N2 . NAG B 2 . ? 60.166 45.850 13.056 1.00 46.41 ? 2001 NAG A N2 1 HETATM 8191 O O3 . NAG B 2 . ? 60.837 43.223 14.877 1.00 44.19 ? 2001 NAG A O3 1 HETATM 8192 O O4 . NAG B 2 . ? 59.302 41.248 13.577 1.00 43.32 ? 2001 NAG A O4 1 HETATM 8193 O O5 . NAG B 2 . ? 57.649 44.344 12.460 1.00 41.07 ? 2001 NAG A O5 1 HETATM 8194 O O6 . NAG B 2 . ? 55.646 42.217 11.800 1.00 46.81 ? 2001 NAG A O6 1 HETATM 8195 O O7 . NAG B 2 . ? 62.350 46.103 12.628 1.00 49.76 ? 2001 NAG A O7 1 HETATM 8196 ZN ZN . ZN C 3 . ? 34.871 64.380 7.978 1.00 13.41 ? 2004 ZN A ZN 1 HETATM 8197 C C5 . GUL D 4 . ? 30.362 66.077 6.652 1.00 10.61 ? 2003 GUL A C5 1 HETATM 8198 C C2 . GUL D 4 . ? 32.477 65.776 8.807 1.00 10.32 ? 2003 GUL A C2 1 HETATM 8199 F F1 . GUL D 4 . ? 29.686 65.550 5.777 1.00 10.76 ? 2003 GUL A F1 1 HETATM 8200 O O2 . GUL D 4 . ? 33.498 65.424 9.560 1.00 9.02 ? 2003 GUL A O2 1 HETATM 8201 C C3 . GUL D 4 . ? 32.845 66.491 7.447 1.00 10.28 ? 2003 GUL A C3 1 HETATM 8202 O O3 . GUL D 4 . ? 34.124 66.129 6.993 1.00 7.71 ? 2003 GUL A O3 1 HETATM 8203 C C4 . GUL D 4 . ? 31.871 66.573 6.138 1.00 9.67 ? 2003 GUL A C4 1 HETATM 8204 O O4 . GUL D 4 . ? 31.641 67.595 5.377 1.00 10.57 ? 2003 GUL A O4 1 HETATM 8205 C C6 . GUL D 4 . ? 29.422 67.142 7.300 1.00 11.16 ? 2003 GUL A C6 1 HETATM 8206 O O6 . GUL D 4 . ? 28.553 66.911 7.997 1.00 12.73 ? 2003 GUL A O6 1 HETATM 8207 O O . GUL D 4 . ? 30.351 65.005 7.757 1.00 9.68 ? 2003 GUL A O 1 HETATM 8208 C C1 . GUL D 4 . ? 31.572 64.548 8.326 1.00 11.88 ? 2003 GUL A C1 1 HETATM 8209 C C1 . MPD E 5 . ? 14.689 61.022 10.167 1.00 23.06 ? 2002 MPD A C1 1 HETATM 8210 C C2 . MPD E 5 . ? 16.106 61.166 10.571 1.00 23.33 ? 2002 MPD A C2 1 HETATM 8211 O O2 . MPD E 5 . ? 16.876 60.155 9.860 1.00 24.86 ? 2002 MPD A O2 1 HETATM 8212 C CM . MPD E 5 . ? 16.637 62.530 10.179 1.00 23.78 ? 2002 MPD A CM 1 HETATM 8213 C C3 . MPD E 5 . ? 16.226 60.890 12.093 1.00 21.03 ? 2002 MPD A C3 1 HETATM 8214 C C4 . MPD E 5 . ? 17.614 60.675 12.682 1.00 21.08 ? 2002 MPD A C4 1 HETATM 8215 O O4 . MPD E 5 . ? 17.550 59.746 13.762 1.00 18.45 ? 2002 MPD A O4 1 HETATM 8216 C C5 . MPD E 5 . ? 18.195 62.001 13.231 1.00 19.75 ? 2002 MPD A C5 1 HETATM 8217 O O . HOH F 6 . ? 42.053 63.617 -7.277 1.00 9.34 ? 2005 HOH A O 1 HETATM 8218 O O . HOH F 6 . ? 53.644 64.955 -19.951 1.00 5.01 ? 2006 HOH A O 1 HETATM 8219 O O . HOH F 6 . ? 39.140 62.880 -19.211 1.00 6.28 ? 2007 HOH A O 1 HETATM 8220 O O . HOH F 6 . ? 52.282 54.192 -4.857 1.00 6.41 ? 2008 HOH A O 1 HETATM 8221 O O . HOH F 6 . ? 56.143 53.409 -0.722 1.00 4.89 ? 2009 HOH A O 1 HETATM 8222 O O . HOH F 6 . ? 31.305 50.013 -24.089 1.00 6.01 ? 2010 HOH A O 1 HETATM 8223 O O . HOH F 6 . ? 49.904 48.559 1.252 1.00 3.28 ? 2011 HOH A O 1 HETATM 8224 O O . HOH F 6 . ? 36.693 57.823 13.416 1.00 7.35 ? 2012 HOH A O 1 HETATM 8225 O O . HOH F 6 . ? 26.757 69.064 -9.276 1.00 10.36 ? 2013 HOH A O 1 HETATM 8226 O O . HOH F 6 . ? 39.271 64.806 -14.871 1.00 11.95 ? 2014 HOH A O 1 HETATM 8227 O O . HOH F 6 . ? 34.228 58.672 -8.736 1.00 8.59 ? 2015 HOH A O 1 HETATM 8228 O O . HOH F 6 . ? 61.062 59.802 -8.350 1.00 9.06 ? 2016 HOH A O 1 HETATM 8229 O O . HOH F 6 . ? 36.637 72.703 0.132 1.00 9.50 ? 2017 HOH A O 1 HETATM 8230 O O . HOH F 6 . ? 31.670 47.057 -8.081 1.00 7.27 ? 2018 HOH A O 1 HETATM 8231 O O . HOH F 6 . ? 30.166 55.902 17.326 1.00 8.94 ? 2019 HOH A O 1 HETATM 8232 O O . HOH F 6 . ? 26.164 49.679 -13.728 1.00 5.60 ? 2020 HOH A O 1 HETATM 8233 O O . HOH F 6 . ? 37.663 52.274 -21.108 1.00 10.55 ? 2021 HOH A O 1 HETATM 8234 O O . HOH F 6 . ? 33.020 62.816 0.104 1.00 8.32 ? 2022 HOH A O 1 HETATM 8235 O O . HOH F 6 . ? 24.716 52.994 -11.714 1.00 8.61 ? 2023 HOH A O 1 HETATM 8236 O O . HOH F 6 . ? 63.106 61.383 -7.645 1.00 5.99 ? 2024 HOH A O 1 HETATM 8237 O O . HOH F 6 . ? 41.192 59.192 13.281 1.00 9.36 ? 2025 HOH A O 1 HETATM 8238 O O . HOH F 6 . ? 47.303 55.894 -15.410 1.00 10.25 ? 2026 HOH A O 1 HETATM 8239 O O . HOH F 6 . ? 56.249 55.845 -2.180 1.00 8.27 ? 2027 HOH A O 1 HETATM 8240 O O . HOH F 6 . ? 67.347 60.787 -5.742 1.00 12.30 ? 2028 HOH A O 1 HETATM 8241 O O . HOH F 6 . ? 26.193 48.813 -10.986 1.00 10.33 ? 2029 HOH A O 1 HETATM 8242 O O . HOH F 6 . ? 65.656 60.310 -7.833 1.00 12.06 ? 2030 HOH A O 1 HETATM 8243 O O . HOH F 6 . ? 32.572 60.205 -1.885 1.00 9.63 ? 2031 HOH A O 1 HETATM 8244 O O . HOH F 6 . ? 20.039 54.783 16.181 1.00 15.91 ? 2032 HOH A O 1 HETATM 8245 O O . HOH F 6 . ? 23.673 55.562 -23.385 1.00 7.19 ? 2033 HOH A O 1 HETATM 8246 O O . HOH F 6 . ? 39.262 57.445 14.776 1.00 9.02 ? 2034 HOH A O 1 HETATM 8247 O O . HOH F 6 . ? 20.255 58.815 -21.835 1.00 10.40 ? 2035 HOH A O 1 HETATM 8248 O O . HOH F 6 . ? 27.866 61.156 19.451 1.00 7.62 ? 2036 HOH A O 1 HETATM 8249 O O . HOH F 6 . ? 33.982 56.353 -26.377 1.00 7.55 ? 2037 HOH A O 1 HETATM 8250 O O . HOH F 6 . ? 26.337 40.071 7.936 1.00 12.67 ? 2038 HOH A O 1 HETATM 8251 O O . HOH F 6 . ? 63.775 50.230 -13.987 1.00 8.03 ? 2039 HOH A O 1 HETATM 8252 O O . HOH F 6 . ? 37.477 57.094 1.721 1.00 8.41 ? 2040 HOH A O 1 HETATM 8253 O O . HOH F 6 . ? 24.098 42.024 6.791 1.00 7.04 ? 2041 HOH A O 1 HETATM 8254 O O . HOH F 6 . ? 31.825 65.492 18.768 1.00 12.93 ? 2042 HOH A O 1 HETATM 8255 O O . HOH F 6 . ? 51.491 56.632 -5.688 1.00 7.48 ? 2043 HOH A O 1 HETATM 8256 O O . HOH F 6 . ? 19.908 56.101 7.168 1.00 9.43 ? 2044 HOH A O 1 HETATM 8257 O O . HOH F 6 . ? 28.240 43.996 13.230 1.00 9.56 ? 2045 HOH A O 1 HETATM 8258 O O . HOH F 6 . ? 30.190 58.566 -11.778 1.00 5.91 ? 2046 HOH A O 1 HETATM 8259 O O . HOH F 6 . ? 64.995 59.386 -3.731 1.00 11.62 ? 2047 HOH A O 1 HETATM 8260 O O . HOH F 6 . ? 46.297 67.652 -15.713 1.00 11.24 ? 2048 HOH A O 1 HETATM 8261 O O . HOH F 6 . ? 60.755 58.380 -3.022 1.00 10.37 ? 2049 HOH A O 1 HETATM 8262 O O . HOH F 6 . ? 60.603 62.340 -1.423 1.00 13.92 ? 2050 HOH A O 1 HETATM 8263 O O . HOH F 6 . ? 53.656 59.917 -9.492 1.00 11.01 ? 2051 HOH A O 1 HETATM 8264 O O . HOH F 6 . ? 18.660 51.072 -12.410 1.00 12.43 ? 2052 HOH A O 1 HETATM 8265 O O . HOH F 6 . ? 28.885 42.825 -11.906 1.00 13.50 ? 2053 HOH A O 1 HETATM 8266 O O . HOH F 6 . ? 34.577 79.172 -9.349 1.00 8.81 ? 2054 HOH A O 1 HETATM 8267 O O . HOH F 6 . ? 21.625 58.017 -7.848 1.00 10.23 ? 2055 HOH A O 1 HETATM 8268 O O . HOH F 6 . ? 37.055 71.832 -4.643 1.00 6.67 ? 2056 HOH A O 1 HETATM 8269 O O . HOH F 6 . ? 55.719 59.428 -11.618 1.00 9.15 ? 2057 HOH A O 1 HETATM 8270 O O . HOH F 6 . ? 36.760 44.942 -5.449 1.00 10.13 ? 2058 HOH A O 1 HETATM 8271 O O . HOH F 6 . ? 51.285 53.411 -24.070 1.00 11.23 ? 2059 HOH A O 1 HETATM 8272 O O . HOH F 6 . ? 35.087 50.661 -17.638 1.00 13.62 ? 2060 HOH A O 1 HETATM 8273 O O . HOH F 6 . ? 60.613 54.877 -0.327 1.00 13.14 ? 2061 HOH A O 1 HETATM 8274 O O . HOH F 6 . ? 42.950 56.924 6.032 1.00 8.16 ? 2062 HOH A O 1 HETATM 8275 O O . HOH F 6 . ? 47.846 59.296 -25.715 1.00 9.86 ? 2063 HOH A O 1 HETATM 8276 O O . HOH F 6 . ? 37.993 73.421 -2.431 1.00 12.70 ? 2064 HOH A O 1 HETATM 8277 O O . HOH F 6 . ? 19.321 55.374 11.495 1.00 11.72 ? 2065 HOH A O 1 HETATM 8278 O O . HOH F 6 . ? 25.997 39.737 5.192 1.00 10.21 ? 2066 HOH A O 1 HETATM 8279 O O . HOH F 6 . ? 23.352 54.235 -3.625 1.00 8.27 ? 2067 HOH A O 1 HETATM 8280 O O . HOH F 6 . ? 34.236 52.497 -1.136 1.00 12.03 ? 2068 HOH A O 1 HETATM 8281 O O . HOH F 6 . ? 50.993 44.239 -8.043 1.00 8.07 ? 2069 HOH A O 1 HETATM 8282 O O . HOH F 6 . ? 37.526 59.011 10.990 1.00 12.88 ? 2070 HOH A O 1 HETATM 8283 O O . HOH F 6 . ? 16.431 49.081 24.006 1.00 14.29 ? 2071 HOH A O 1 HETATM 8284 O O . HOH F 6 . ? 19.318 53.520 8.094 1.00 11.36 ? 2072 HOH A O 1 HETATM 8285 O O . HOH F 6 . ? 11.757 51.608 14.240 1.00 12.22 ? 2073 HOH A O 1 HETATM 8286 O O . HOH F 6 . ? 16.946 56.220 10.121 1.00 8.71 ? 2074 HOH A O 1 HETATM 8287 O O . HOH F 6 . ? 67.986 65.709 -3.559 1.00 15.30 ? 2075 HOH A O 1 HETATM 8288 O O . HOH F 6 . ? 22.854 53.189 -24.426 1.00 12.29 ? 2076 HOH A O 1 HETATM 8289 O O . HOH F 6 . ? 52.099 50.745 6.287 1.00 9.26 ? 2077 HOH A O 1 HETATM 8290 O O . HOH F 6 . ? 17.643 52.944 6.182 1.00 11.43 ? 2078 HOH A O 1 HETATM 8291 O O . HOH F 6 . ? 68.871 58.292 -5.113 1.00 9.20 ? 2079 HOH A O 1 HETATM 8292 O O . HOH F 6 . ? 33.474 48.140 -10.197 1.00 7.92 ? 2080 HOH A O 1 HETATM 8293 O O . HOH F 6 . ? 26.809 41.636 -13.205 1.00 8.17 ? 2081 HOH A O 1 HETATM 8294 O O . HOH F 6 . ? 26.739 60.966 -3.340 1.00 8.73 ? 2082 HOH A O 1 HETATM 8295 O O . HOH F 6 . ? 49.455 62.281 -8.648 1.00 13.73 ? 2083 HOH A O 1 HETATM 8296 O O . HOH F 6 . ? 41.025 52.290 -17.031 1.00 10.76 ? 2084 HOH A O 1 HETATM 8297 O O . HOH F 6 . ? 31.356 76.846 -6.352 1.00 13.71 ? 2085 HOH A O 1 HETATM 8298 O O . HOH F 6 . ? 43.342 68.270 -24.992 1.00 11.65 ? 2086 HOH A O 1 HETATM 8299 O O . HOH F 6 . ? 32.762 81.088 -11.732 1.00 10.51 ? 2087 HOH A O 1 HETATM 8300 O O . HOH F 6 . ? 20.537 66.281 -19.511 1.00 9.74 ? 2088 HOH A O 1 HETATM 8301 O O . HOH F 6 . ? 40.430 62.751 6.188 1.00 7.78 ? 2089 HOH A O 1 HETATM 8302 O O . HOH F 6 . ? 42.184 47.375 -24.579 1.00 12.73 ? 2090 HOH A O 1 HETATM 8303 O O . HOH F 6 . ? 44.523 41.952 -0.508 1.00 15.95 ? 2091 HOH A O 1 HETATM 8304 O O . HOH F 6 . ? 38.622 55.267 -31.806 1.00 15.33 ? 2092 HOH A O 1 HETATM 8305 O O . HOH F 6 . ? 22.291 54.438 -12.026 1.00 10.60 ? 2093 HOH A O 1 HETATM 8306 O O . HOH F 6 . ? 48.226 89.319 -30.848 1.00 11.65 ? 2094 HOH A O 1 HETATM 8307 O O . HOH F 6 . ? 36.802 51.761 3.744 1.00 7.55 ? 2095 HOH A O 1 HETATM 8308 O O . HOH F 6 . ? 38.873 62.161 8.120 1.00 11.36 ? 2096 HOH A O 1 HETATM 8309 O O . HOH F 6 . ? 47.450 46.097 3.632 1.00 8.88 ? 2097 HOH A O 1 HETATM 8310 O O . HOH F 6 . ? 33.505 57.119 -35.995 1.00 11.34 ? 2098 HOH A O 1 HETATM 8311 O O . HOH F 6 . ? 32.358 77.648 -29.683 1.00 11.34 ? 2099 HOH A O 1 HETATM 8312 O O . HOH F 6 . ? 39.231 39.145 17.209 1.00 14.03 ? 2100 HOH A O 1 HETATM 8313 O O . HOH F 6 . ? 35.936 53.159 1.331 1.00 8.81 ? 2101 HOH A O 1 HETATM 8314 O O . HOH F 6 . ? 14.367 60.133 5.110 1.00 11.15 ? 2102 HOH A O 1 HETATM 8315 O O . HOH F 6 . ? 21.599 57.172 4.937 1.00 12.36 ? 2103 HOH A O 1 HETATM 8316 O O . HOH F 6 . ? 43.058 48.111 11.229 1.00 11.94 ? 2104 HOH A O 1 HETATM 8317 O O . HOH F 6 . ? 26.124 72.779 5.640 1.00 7.22 ? 2105 HOH A O 1 HETATM 8318 O O . HOH F 6 . ? 27.339 48.577 -21.552 1.00 16.62 ? 2106 HOH A O 1 HETATM 8319 O O . HOH F 6 . ? 33.404 78.742 -5.144 1.00 10.92 ? 2107 HOH A O 1 HETATM 8320 O O . HOH F 6 . ? 49.961 59.454 -11.619 1.00 14.18 ? 2108 HOH A O 1 HETATM 8321 O O . HOH F 6 . ? 25.635 51.288 -9.611 1.00 9.33 ? 2109 HOH A O 1 HETATM 8322 O O . HOH F 6 . ? 40.188 56.365 5.751 1.00 10.92 ? 2110 HOH A O 1 HETATM 8323 O O . HOH F 6 . ? 14.086 59.829 -3.502 1.00 10.57 ? 2111 HOH A O 1 HETATM 8324 O O . HOH F 6 . ? 19.694 53.547 -11.797 1.00 8.68 ? 2112 HOH A O 1 HETATM 8325 O O . HOH F 6 . ? 26.232 63.691 16.987 1.00 16.63 ? 2113 HOH A O 1 HETATM 8326 O O . HOH F 6 . ? 19.853 57.420 -11.962 1.00 12.48 ? 2114 HOH A O 1 HETATM 8327 O O . HOH F 6 . ? 47.211 48.520 11.521 1.00 17.21 ? 2115 HOH A O 1 HETATM 8328 O O . HOH F 6 . ? 67.787 81.623 -25.759 1.00 10.35 ? 2116 HOH A O 1 HETATM 8329 O O . HOH F 6 . ? 22.841 51.623 -8.799 1.00 14.96 ? 2117 HOH A O 1 HETATM 8330 O O . HOH F 6 . ? 46.584 70.314 -36.697 1.00 11.89 ? 2118 HOH A O 1 HETATM 8331 O O . HOH F 6 . ? 20.584 57.516 -5.286 1.00 10.03 ? 2119 HOH A O 1 HETATM 8332 O O . HOH F 6 . ? 18.094 60.671 24.463 1.00 13.80 ? 2120 HOH A O 1 HETATM 8333 O O . HOH F 6 . ? 41.188 68.466 -32.637 1.00 18.09 ? 2121 HOH A O 1 HETATM 8334 O O . HOH F 6 . ? 38.368 40.036 1.758 1.00 11.09 ? 2122 HOH A O 1 HETATM 8335 O O . HOH F 6 . ? 23.812 58.194 6.319 1.00 9.48 ? 2123 HOH A O 1 HETATM 8336 O O . HOH F 6 . ? 18.121 59.824 -20.096 1.00 16.97 ? 2124 HOH A O 1 HETATM 8337 O O . HOH F 6 . ? 41.302 77.569 -14.229 1.00 13.84 ? 2125 HOH A O 1 HETATM 8338 O O . HOH F 6 . ? 52.851 58.999 -1.745 1.00 17.06 ? 2126 HOH A O 1 HETATM 8339 O O . HOH F 6 . ? 47.902 49.535 13.700 1.00 10.68 ? 2127 HOH A O 1 HETATM 8340 O O . HOH F 6 . ? 35.184 43.654 28.708 1.00 14.48 ? 2128 HOH A O 1 HETATM 8341 O O . HOH F 6 . ? 59.532 60.553 -6.319 1.00 11.98 ? 2129 HOH A O 1 HETATM 8342 O O . HOH F 6 . ? 53.667 72.534 -19.355 1.00 10.69 ? 2130 HOH A O 1 HETATM 8343 O O . HOH F 6 . ? 39.693 53.934 -20.929 1.00 10.82 ? 2131 HOH A O 1 HETATM 8344 O O . HOH F 6 . ? 33.130 36.759 -4.405 1.00 18.25 ? 2132 HOH A O 1 HETATM 8345 O O . HOH F 6 . ? 14.424 63.996 -16.367 1.00 15.26 ? 2133 HOH A O 1 HETATM 8346 O O . HOH F 6 . ? 47.482 42.991 -2.507 1.00 18.50 ? 2134 HOH A O 1 HETATM 8347 O O . HOH F 6 . ? 46.873 55.842 -25.631 1.00 18.34 ? 2135 HOH A O 1 HETATM 8348 O O . HOH F 6 . ? 32.010 58.627 -28.537 1.00 14.44 ? 2136 HOH A O 1 HETATM 8349 O O . HOH F 6 . ? 49.185 50.170 28.205 1.00 11.81 ? 2137 HOH A O 1 HETATM 8350 O O . HOH F 6 . ? 26.391 37.510 29.418 1.00 16.66 ? 2138 HOH A O 1 HETATM 8351 O O . HOH F 6 . ? 51.895 46.645 1.247 1.00 9.65 ? 2139 HOH A O 1 HETATM 8352 O O . HOH F 6 . ? 41.666 58.751 -16.170 1.00 11.24 ? 2140 HOH A O 1 HETATM 8353 O O . HOH F 6 . ? 13.800 54.161 4.332 1.00 16.13 ? 2141 HOH A O 1 HETATM 8354 O O . HOH F 6 . ? 67.703 78.985 -25.496 1.00 8.64 ? 2142 HOH A O 1 HETATM 8355 O O . HOH F 6 . ? 42.047 75.122 -16.251 1.00 18.33 ? 2143 HOH A O 1 HETATM 8356 O O . HOH F 6 . ? 23.002 56.140 30.782 1.00 15.98 ? 2144 HOH A O 1 HETATM 8357 O O . HOH F 6 . ? 56.945 61.059 1.451 1.00 15.40 ? 2145 HOH A O 1 HETATM 8358 O O . HOH F 6 . ? 20.137 74.429 -6.857 1.00 10.82 ? 2146 HOH A O 1 HETATM 8359 O O . HOH F 6 . ? 13.448 53.674 1.760 1.00 20.46 ? 2147 HOH A O 1 HETATM 8360 O O . HOH F 6 . ? 34.145 34.462 16.116 1.00 18.74 ? 2148 HOH A O 1 HETATM 8361 O O . HOH F 6 . ? 33.962 64.536 -32.288 1.00 13.91 ? 2149 HOH A O 1 HETATM 8362 O O . HOH F 6 . ? 13.945 49.111 15.388 1.00 11.48 ? 2150 HOH A O 1 HETATM 8363 O O . HOH F 6 . ? 30.237 35.273 -12.426 1.00 20.50 ? 2151 HOH A O 1 HETATM 8364 O O . HOH F 6 . ? 18.269 54.971 14.092 1.00 12.18 ? 2152 HOH A O 1 HETATM 8365 O O . HOH F 6 . ? 15.405 60.381 15.462 1.00 18.18 ? 2153 HOH A O 1 HETATM 8366 O O . HOH F 6 . ? 16.914 74.752 -3.252 1.00 12.85 ? 2154 HOH A O 1 HETATM 8367 O O . HOH F 6 . ? 56.586 46.210 -17.494 1.00 12.49 ? 2155 HOH A O 1 HETATM 8368 O O . HOH F 6 . ? 45.687 59.891 -18.372 1.00 9.25 ? 2156 HOH A O 1 HETATM 8369 O O . HOH F 6 . ? 28.043 84.564 -35.546 1.00 12.42 ? 2157 HOH A O 1 HETATM 8370 O O . HOH F 6 . ? 73.049 65.201 -7.942 1.00 16.36 ? 2158 HOH A O 1 HETATM 8371 O O . HOH F 6 . ? 73.825 65.913 -17.783 1.00 14.89 ? 2159 HOH A O 1 HETATM 8372 O O . HOH F 6 . ? 59.283 50.048 -0.642 1.00 15.14 ? 2160 HOH A O 1 HETATM 8373 O O . HOH F 6 . ? 23.208 78.526 -24.767 1.00 20.95 ? 2161 HOH A O 1 HETATM 8374 O O . HOH F 6 . ? 14.396 54.458 -16.149 1.00 14.24 ? 2162 HOH A O 1 HETATM 8375 O O . HOH F 6 . ? 43.484 73.198 5.601 1.00 10.34 ? 2163 HOH A O 1 HETATM 8376 O O . HOH F 6 . ? 11.930 55.100 -12.462 1.00 17.12 ? 2164 HOH A O 1 HETATM 8377 O O . HOH F 6 . ? 63.608 44.622 -6.958 1.00 12.60 ? 2165 HOH A O 1 HETATM 8378 O O . HOH F 6 . ? 24.770 51.119 -24.156 1.00 13.89 ? 2166 HOH A O 1 HETATM 8379 O O . HOH F 6 . ? 35.425 45.292 -27.537 1.00 11.12 ? 2167 HOH A O 1 HETATM 8380 O O . HOH F 6 . ? 28.663 49.907 -24.565 1.00 16.62 ? 2168 HOH A O 1 HETATM 8381 O O . HOH F 6 . ? 54.871 80.982 -23.632 1.00 16.05 ? 2169 HOH A O 1 HETATM 8382 O O . HOH F 6 . ? 24.096 63.406 7.467 1.00 7.11 ? 2170 HOH A O 1 HETATM 8383 O O . HOH F 6 . ? 49.754 57.618 -7.659 1.00 11.84 ? 2171 HOH A O 1 HETATM 8384 O O . HOH F 6 . ? 46.200 70.964 -0.006 1.00 20.21 ? 2172 HOH A O 1 HETATM 8385 O O . HOH F 6 . ? 24.373 55.678 -1.944 1.00 11.62 ? 2173 HOH A O 1 HETATM 8386 O O . HOH F 6 . ? 28.668 41.292 -21.673 1.00 12.02 ? 2174 HOH A O 1 HETATM 8387 O O . HOH F 6 . ? 36.965 45.705 27.429 1.00 11.33 ? 2175 HOH A O 1 HETATM 8388 O O . HOH F 6 . ? 41.432 41.307 -17.672 1.00 13.78 ? 2176 HOH A O 1 HETATM 8389 O O . HOH F 6 . ? 40.369 62.584 -32.081 1.00 13.82 ? 2177 HOH A O 1 HETATM 8390 O O . HOH F 6 . ? 49.295 59.254 -28.804 1.00 8.76 ? 2178 HOH A O 1 HETATM 8391 O O . HOH F 6 . ? 64.315 39.449 -10.404 1.00 23.44 ? 2179 HOH A O 1 HETATM 8392 O O . HOH F 6 . ? 19.274 72.489 3.031 1.00 19.25 ? 2180 HOH A O 1 HETATM 8393 O O . HOH F 6 . ? 17.105 70.403 -16.265 1.00 12.20 ? 2181 HOH A O 1 HETATM 8394 O O . HOH F 6 . ? 9.418 52.385 16.873 1.00 20.78 ? 2182 HOH A O 1 HETATM 8395 O O . HOH F 6 . ? 53.872 71.187 -36.940 1.00 8.43 ? 2183 HOH A O 1 HETATM 8396 O O . HOH F 6 . ? 50.869 70.908 -23.552 1.00 18.03 ? 2184 HOH A O 1 HETATM 8397 O O . HOH F 6 . ? 49.420 44.192 4.329 1.00 14.24 ? 2185 HOH A O 1 HETATM 8398 O O . HOH F 6 . ? 59.569 68.035 2.340 1.00 25.46 ? 2186 HOH A O 1 HETATM 8399 O O . HOH F 6 . ? 25.376 53.885 11.065 1.00 11.54 ? 2187 HOH A O 1 HETATM 8400 O O . HOH F 6 . ? 69.055 61.434 -2.533 1.00 10.95 ? 2188 HOH A O 1 HETATM 8401 O O . HOH F 6 . ? 58.193 77.321 -38.606 1.00 12.53 ? 2189 HOH A O 1 HETATM 8402 O O . HOH F 6 . ? 44.362 46.271 9.961 1.00 11.90 ? 2190 HOH A O 1 HETATM 8403 O O . HOH F 6 . ? 46.557 57.401 -18.814 1.00 10.69 ? 2191 HOH A O 1 HETATM 8404 O O . HOH F 6 . ? 33.619 83.525 -10.434 1.00 14.63 ? 2192 HOH A O 1 HETATM 8405 O O . HOH F 6 . ? 47.007 68.439 -30.380 1.00 12.84 ? 2193 HOH A O 1 HETATM 8406 O O . HOH F 6 . ? 44.560 56.166 -15.456 1.00 14.78 ? 2194 HOH A O 1 HETATM 8407 O O . HOH F 6 . ? 13.194 66.972 -4.771 1.00 12.11 ? 2195 HOH A O 1 HETATM 8408 O O . HOH F 6 . ? 24.449 39.212 -11.483 1.00 18.69 ? 2196 HOH A O 1 HETATM 8409 O O . HOH F 6 . ? 41.550 61.194 -29.800 1.00 12.79 ? 2197 HOH A O 1 HETATM 8410 O O . HOH F 6 . ? 27.121 41.380 13.330 1.00 14.36 ? 2198 HOH A O 1 HETATM 8411 O O . HOH F 6 . ? 41.995 87.831 -40.922 1.00 11.33 ? 2199 HOH A O 1 HETATM 8412 O O . HOH F 6 . ? 69.895 69.948 -12.816 1.00 14.09 ? 2200 HOH A O 1 HETATM 8413 O O . HOH F 6 . ? 64.149 77.841 -35.324 1.00 14.19 ? 2201 HOH A O 1 HETATM 8414 O O . HOH F 6 . ? 20.676 65.396 7.797 1.00 11.16 ? 2202 HOH A O 1 HETATM 8415 O O . HOH F 6 . ? 11.326 61.469 -18.483 1.00 22.94 ? 2203 HOH A O 1 HETATM 8416 O O . HOH F 6 . ? 24.604 70.695 -8.790 1.00 10.86 ? 2204 HOH A O 1 HETATM 8417 O O . HOH F 6 . ? 25.077 39.996 14.172 1.00 16.67 ? 2205 HOH A O 1 HETATM 8418 O O . HOH F 6 . ? 22.612 63.321 -33.105 1.00 20.74 ? 2206 HOH A O 1 HETATM 8419 O O . HOH F 6 . ? 41.729 43.268 7.926 1.00 13.51 ? 2207 HOH A O 1 HETATM 8420 O O . HOH F 6 . ? 13.448 58.013 -22.074 1.00 13.32 ? 2208 HOH A O 1 HETATM 8421 O O . HOH F 6 . ? 41.456 50.447 33.318 1.00 26.36 ? 2209 HOH A O 1 HETATM 8422 O O . HOH F 6 . ? 45.925 52.971 -19.449 1.00 18.80 ? 2210 HOH A O 1 HETATM 8423 O O . HOH F 6 . ? 51.203 76.341 -41.220 1.00 24.82 ? 2211 HOH A O 1 HETATM 8424 O O . HOH F 6 . ? 25.650 86.311 -31.938 1.00 14.58 ? 2212 HOH A O 1 HETATM 8425 O O . HOH F 6 . ? 12.374 56.301 5.294 1.00 18.66 ? 2213 HOH A O 1 HETATM 8426 O O . HOH F 6 . ? 22.543 56.827 -34.233 1.00 15.69 ? 2214 HOH A O 1 HETATM 8427 O O . HOH F 6 . ? 43.558 72.605 -42.004 1.00 27.06 ? 2215 HOH A O 1 HETATM 8428 O O . HOH F 6 . ? 44.488 58.689 -16.074 1.00 17.59 ? 2216 HOH A O 1 HETATM 8429 O O . HOH F 6 . ? 31.558 81.641 0.389 1.00 18.81 ? 2217 HOH A O 1 HETATM 8430 O O . HOH F 6 . ? 52.044 56.404 -30.413 1.00 20.27 ? 2218 HOH A O 1 HETATM 8431 O O . HOH F 6 . ? 17.362 70.105 -23.438 1.00 19.41 ? 2219 HOH A O 1 HETATM 8432 O O . HOH F 6 . ? 37.594 47.059 29.700 1.00 17.22 ? 2220 HOH A O 1 HETATM 8433 O O . HOH F 6 . ? 49.710 55.079 -29.145 1.00 20.27 ? 2221 HOH A O 1 HETATM 8434 O O . HOH F 6 . ? 36.251 79.023 -5.159 1.00 19.03 ? 2222 HOH A O 1 HETATM 8435 O O . HOH F 6 . ? 62.140 62.628 25.769 1.00 16.58 ? 2223 HOH A O 1 HETATM 8436 O O . HOH F 6 . ? 11.333 53.295 6.729 1.00 19.83 ? 2224 HOH A O 1 HETATM 8437 O O . HOH F 6 . ? 13.883 60.861 -22.376 1.00 14.70 ? 2225 HOH A O 1 HETATM 8438 O O . HOH F 6 . ? 50.589 62.092 26.292 1.00 18.12 ? 2226 HOH A O 1 HETATM 8439 O O . HOH F 6 . ? 68.559 78.848 -18.248 1.00 23.14 ? 2227 HOH A O 1 HETATM 8440 O O . HOH F 6 . ? 84.236 68.263 -17.338 1.00 17.18 ? 2228 HOH A O 1 HETATM 8441 O O . HOH F 6 . ? 21.831 40.582 -8.830 1.00 38.70 ? 2229 HOH A O 1 HETATM 8442 O O . HOH F 6 . ? 52.881 69.920 18.341 1.00 20.10 ? 2230 HOH A O 1 HETATM 8443 O O . HOH F 6 . ? 42.705 53.574 35.555 1.00 23.17 ? 2231 HOH A O 1 HETATM 8444 O O . HOH F 6 . ? 70.571 52.035 -12.681 1.00 13.14 ? 2232 HOH A O 1 HETATM 8445 O O . HOH F 6 . ? 34.692 71.242 13.476 1.00 23.06 ? 2233 HOH A O 1 HETATM 8446 O O . HOH F 6 . ? 27.253 46.304 13.635 1.00 18.40 ? 2234 HOH A O 1 HETATM 8447 O O . HOH F 6 . ? 14.116 49.703 19.712 1.00 18.81 ? 2235 HOH A O 1 HETATM 8448 O O . HOH F 6 . ? 49.735 73.377 -21.811 1.00 17.75 ? 2236 HOH A O 1 HETATM 8449 O O . HOH F 6 . ? 48.772 44.401 -6.109 1.00 23.47 ? 2237 HOH A O 1 HETATM 8450 O O . HOH F 6 . ? 61.375 76.782 -39.856 1.00 14.28 ? 2238 HOH A O 1 HETATM 8451 O O . HOH F 6 . ? 22.663 78.760 -30.337 1.00 18.64 ? 2239 HOH A O 1 HETATM 8452 O O . HOH F 6 . ? 43.484 88.575 -38.668 1.00 16.46 ? 2240 HOH A O 1 HETATM 8453 O O . HOH F 6 . ? 35.757 77.606 -7.327 1.00 12.80 ? 2241 HOH A O 1 HETATM 8454 O O . HOH F 6 . ? 24.661 68.341 21.837 1.00 16.51 ? 2242 HOH A O 1 HETATM 8455 O O . HOH F 6 . ? 68.126 49.343 -1.043 1.00 27.22 ? 2243 HOH A O 1 HETATM 8456 O O . HOH F 6 . ? 54.045 47.879 15.568 1.00 19.12 ? 2244 HOH A O 1 HETATM 8457 O O . HOH F 6 . ? 54.959 50.554 16.890 1.00 24.94 ? 2245 HOH A O 1 HETATM 8458 O O . HOH F 6 . ? 39.174 48.778 -33.062 1.00 22.62 ? 2246 HOH A O 1 HETATM 8459 O O . HOH F 6 . ? 22.847 45.218 -13.586 1.00 20.26 ? 2247 HOH A O 1 HETATM 8460 O O . HOH F 6 . ? 67.047 55.273 0.924 1.00 12.93 ? 2248 HOH A O 1 HETATM 8461 O O . HOH F 6 . ? 48.050 44.009 -8.694 1.00 23.66 ? 2249 HOH A O 1 HETATM 8462 O O . HOH F 6 . ? 26.931 87.894 -23.720 1.00 20.54 ? 2250 HOH A O 1 HETATM 8463 O O . HOH F 6 . ? 18.860 48.818 37.708 1.00 15.24 ? 2251 HOH A O 1 HETATM 8464 O O . HOH F 6 . ? 83.559 67.592 -22.718 1.00 28.92 ? 2252 HOH A O 1 HETATM 8465 O O . HOH F 6 . ? 43.111 59.768 -19.133 1.00 21.15 ? 2253 HOH A O 1 HETATM 8466 O O . HOH F 6 . ? 47.393 78.893 -40.568 1.00 16.40 ? 2254 HOH A O 1 HETATM 8467 O O . HOH F 6 . ? 8.663 57.513 -6.920 1.00 25.68 ? 2255 HOH A O 1 HETATM 8468 O O . HOH F 6 . ? 54.716 90.316 -23.764 1.00 33.07 ? 2256 HOH A O 1 HETATM 8469 O O . HOH F 6 . ? 27.641 36.696 -19.601 1.00 24.16 ? 2257 HOH A O 1 HETATM 8470 O O . HOH F 6 . ? 72.279 59.036 -11.389 1.00 23.47 ? 2258 HOH A O 1 HETATM 8471 O O . HOH F 6 . ? 11.853 59.598 -4.982 1.00 19.00 ? 2259 HOH A O 1 HETATM 8472 O O . HOH F 6 . ? 23.720 46.067 -15.964 1.00 22.13 ? 2260 HOH A O 1 HETATM 8473 O O . HOH F 6 . ? 50.067 70.836 -17.736 1.00 23.16 ? 2261 HOH A O 1 HETATM 8474 O O . HOH F 6 . ? 45.082 90.106 -25.677 1.00 18.81 ? 2262 HOH A O 1 HETATM 8475 O O . HOH F 6 . ? 16.034 72.197 -19.154 1.00 12.70 ? 2263 HOH A O 1 HETATM 8476 O O . HOH F 6 . ? 19.990 52.706 -24.242 1.00 19.23 ? 2264 HOH A O 1 HETATM 8477 O O . HOH F 6 . ? 59.548 76.505 -9.016 1.00 16.11 ? 2265 HOH A O 1 HETATM 8478 O O . HOH F 6 . ? 66.825 60.050 -27.265 1.00 19.37 ? 2266 HOH A O 1 HETATM 8479 O O . HOH F 6 . ? 38.456 51.330 -29.951 1.00 20.62 ? 2267 HOH A O 1 HETATM 8480 O O . HOH F 6 . ? 40.488 82.785 -10.874 1.00 16.67 ? 2268 HOH A O 1 HETATM 8481 O O . HOH F 6 . ? 42.009 48.917 31.251 1.00 16.35 ? 2269 HOH A O 1 HETATM 8482 O O . HOH F 6 . ? 24.129 52.977 -5.955 1.00 19.60 ? 2270 HOH A O 1 HETATM 8483 O O . HOH F 6 . ? 53.258 47.105 -24.978 1.00 14.25 ? 2271 HOH A O 1 HETATM 8484 O O . HOH F 6 . ? 32.393 89.118 -43.111 1.00 22.77 ? 2272 HOH A O 1 HETATM 8485 O O . HOH F 6 . ? 35.990 36.160 -4.565 1.00 18.46 ? 2273 HOH A O 1 HETATM 8486 O O . HOH F 6 . ? 69.993 83.023 -30.059 1.00 33.47 ? 2274 HOH A O 1 HETATM 8487 O O . HOH F 6 . ? 49.610 82.503 -43.944 1.00 15.76 ? 2275 HOH A O 1 HETATM 8488 O O . HOH F 6 . ? 68.282 79.676 -34.763 1.00 24.94 ? 2276 HOH A O 1 HETATM 8489 O O . HOH F 6 . ? 28.968 47.077 37.115 1.00 19.37 ? 2277 HOH A O 1 HETATM 8490 O O . HOH F 6 . ? 18.590 70.040 4.084 1.00 9.66 ? 2278 HOH A O 1 HETATM 8491 O O . HOH F 6 . ? 14.036 68.382 -7.870 1.00 19.47 ? 2279 HOH A O 1 HETATM 8492 O O . HOH F 6 . ? 50.393 72.519 9.297 1.00 25.57 ? 2280 HOH A O 1 HETATM 8493 O O . HOH F 6 . ? 39.497 75.608 -40.298 1.00 16.85 ? 2281 HOH A O 1 HETATM 8494 O O . HOH F 6 . ? 28.639 65.127 19.667 1.00 17.42 ? 2282 HOH A O 1 HETATM 8495 O O . HOH F 6 . ? 11.727 58.611 7.762 1.00 26.79 ? 2283 HOH A O 1 HETATM 8496 O O . HOH F 6 . ? 52.525 78.868 -17.369 1.00 27.33 ? 2284 HOH A O 1 HETATM 8497 O O . HOH F 6 . ? 18.384 65.097 -27.099 1.00 39.67 ? 2285 HOH A O 1 HETATM 8498 O O . HOH F 6 . ? 44.742 79.466 -33.361 1.00 17.11 ? 2286 HOH A O 1 HETATM 8499 O O . HOH F 6 . ? 36.150 81.115 6.287 1.00 24.24 ? 2287 HOH A O 1 HETATM 8500 O O . HOH F 6 . ? 16.725 60.610 -28.321 1.00 20.16 ? 2288 HOH A O 1 HETATM 8501 O O . HOH F 6 . ? 29.669 87.503 -17.861 1.00 33.46 ? 2289 HOH A O 1 HETATM 8502 O O . HOH F 6 . ? 8.705 54.961 -6.185 1.00 25.40 ? 2290 HOH A O 1 HETATM 8503 O O . HOH F 6 . ? 46.636 61.663 -26.106 1.00 18.17 ? 2291 HOH A O 1 HETATM 8504 O O . HOH F 6 . ? 43.144 82.214 -10.216 1.00 16.99 ? 2292 HOH A O 1 HETATM 8505 O O . HOH F 6 . ? 10.313 50.806 18.683 1.00 24.28 ? 2293 HOH A O 1 HETATM 8506 O O . HOH F 6 . ? 12.886 42.602 12.595 1.00 21.72 ? 2294 HOH A O 1 HETATM 8507 O O . HOH F 6 . ? 35.812 45.215 30.830 1.00 23.17 ? 2295 HOH A O 1 HETATM 8508 O O . HOH F 6 . ? 15.750 75.210 -11.699 1.00 21.41 ? 2296 HOH A O 1 HETATM 8509 O O . HOH F 6 . ? 25.288 46.890 -20.892 1.00 23.38 ? 2297 HOH A O 1 HETATM 8510 O O . HOH F 6 . ? 56.885 64.930 24.254 1.00 20.02 ? 2298 HOH A O 1 HETATM 8511 O O . HOH F 6 . ? 38.609 94.155 -42.201 1.00 19.00 ? 2299 HOH A O 1 HETATM 8512 O O . HOH F 6 . ? 34.746 59.650 -34.970 1.00 22.23 ? 2300 HOH A O 1 HETATM 8513 O O . HOH F 6 . ? 32.893 41.059 -17.919 1.00 20.79 ? 2301 HOH A O 1 HETATM 8514 O O . HOH F 6 . ? 20.765 42.691 -7.499 1.00 16.17 ? 2302 HOH A O 1 HETATM 8515 O O . HOH F 6 . ? 19.212 76.739 4.760 1.00 28.72 ? 2303 HOH A O 1 HETATM 8516 O O . HOH F 6 . ? 43.460 80.710 4.976 1.00 22.37 ? 2304 HOH A O 1 HETATM 8517 O O . HOH F 6 . ? 32.949 85.301 -5.596 1.00 21.45 ? 2305 HOH A O 1 HETATM 8518 O O . HOH F 6 . ? 31.342 33.689 2.882 1.00 23.63 ? 2306 HOH A O 1 HETATM 8519 O O . HOH F 6 . ? 21.570 78.567 -1.419 1.00 14.98 ? 2307 HOH A O 1 HETATM 8520 O O . HOH F 6 . ? 55.261 59.140 3.950 1.00 20.68 ? 2308 HOH A O 1 HETATM 8521 O O . HOH F 6 . ? 13.404 62.473 -20.079 1.00 16.65 ? 2309 HOH A O 1 HETATM 8522 O O . HOH F 6 . ? 17.029 50.860 -19.557 1.00 25.66 ? 2310 HOH A O 1 HETATM 8523 O O . HOH F 6 . ? 14.231 62.917 -12.101 1.00 16.38 ? 2311 HOH A O 1 HETATM 8524 O O . HOH F 6 . ? 53.088 86.751 -21.406 1.00 27.02 ? 2312 HOH A O 1 HETATM 8525 O O . HOH F 6 . ? 70.953 49.558 -0.126 1.00 24.83 ? 2313 HOH A O 1 HETATM 8526 O O . HOH F 6 . ? 58.109 42.589 1.562 1.00 23.59 ? 2314 HOH A O 1 HETATM 8527 O O . HOH F 6 . ? 74.605 76.415 -14.442 1.00 24.99 ? 2315 HOH A O 1 HETATM 8528 O O . HOH F 6 . ? 24.950 83.215 -16.965 1.00 20.65 ? 2316 HOH A O 1 HETATM 8529 O O . HOH F 6 . ? 56.853 67.583 -35.449 1.00 21.63 ? 2317 HOH A O 1 HETATM 8530 O O . HOH F 6 . ? 48.824 50.527 -29.534 1.00 19.96 ? 2318 HOH A O 1 HETATM 8531 O O . HOH F 6 . ? 66.597 71.637 -6.825 1.00 19.33 ? 2319 HOH A O 1 HETATM 8532 O O . HOH F 6 . ? 28.784 93.677 -38.605 1.00 17.76 ? 2320 HOH A O 1 HETATM 8533 O O . HOH F 6 . ? 32.615 64.769 -10.138 1.00 17.72 ? 2321 HOH A O 1 HETATM 8534 O O . HOH F 6 . ? 13.345 51.048 -1.842 1.00 26.28 ? 2322 HOH A O 1 HETATM 8535 O O . HOH F 6 . ? 39.428 49.208 30.257 1.00 34.20 ? 2323 HOH A O 1 HETATM 8536 O O . HOH F 6 . ? 67.848 58.680 -24.195 1.00 16.08 ? 2324 HOH A O 1 HETATM 8537 O O . HOH F 6 . ? 20.750 58.924 -34.692 1.00 15.96 ? 2325 HOH A O 1 HETATM 8538 O O . HOH F 6 . ? 37.413 75.644 -42.558 1.00 22.42 ? 2326 HOH A O 1 HETATM 8539 O O . HOH F 6 . ? 31.892 51.241 -35.500 1.00 22.93 ? 2327 HOH A O 1 HETATM 8540 O O . HOH F 6 . ? 12.874 71.128 -0.615 1.00 20.81 ? 2328 HOH A O 1 HETATM 8541 O O . HOH F 6 . ? 36.951 41.073 -24.823 1.00 33.91 ? 2329 HOH A O 1 HETATM 8542 O O . HOH F 6 . ? 19.286 42.807 -2.486 1.00 23.14 ? 2330 HOH A O 1 HETATM 8543 O O . HOH F 6 . ? 50.005 44.103 7.285 1.00 17.93 ? 2331 HOH A O 1 HETATM 8544 O O . HOH F 6 . ? 37.344 45.477 -25.488 1.00 18.54 ? 2332 HOH A O 1 HETATM 8545 O O . HOH F 6 . ? 75.198 74.176 -19.756 1.00 21.74 ? 2333 HOH A O 1 HETATM 8546 O O . HOH F 6 . ? 50.288 61.120 -31.263 1.00 14.65 ? 2334 HOH A O 1 HETATM 8547 O O . HOH F 6 . ? 42.808 56.708 -31.642 1.00 22.38 ? 2335 HOH A O 1 HETATM 8548 O O . HOH F 6 . ? 13.313 68.801 1.022 1.00 20.68 ? 2336 HOH A O 1 HETATM 8549 O O . HOH F 6 . ? 41.124 82.749 -31.461 1.00 26.25 ? 2337 HOH A O 1 HETATM 8550 O O . HOH F 6 . ? 26.883 52.218 22.566 1.00 21.72 ? 2338 HOH A O 1 HETATM 8551 O O . HOH F 6 . ? 12.633 66.466 -9.646 1.00 21.50 ? 2339 HOH A O 1 HETATM 8552 O O . HOH F 6 . ? 42.468 39.354 -15.851 1.00 23.64 ? 2340 HOH A O 1 HETATM 8553 O O . HOH F 6 . ? 48.062 48.439 16.517 1.00 14.54 ? 2341 HOH A O 1 HETATM 8554 O O . HOH F 6 . ? 11.229 46.866 17.760 1.00 22.64 ? 2342 HOH A O 1 HETATM 8555 O O . HOH F 6 . ? 16.377 67.963 -19.774 1.00 19.59 ? 2343 HOH A O 1 HETATM 8556 O O . HOH F 6 . ? 5.229 52.799 -6.070 1.00 29.84 ? 2344 HOH A O 1 HETATM 8557 O O . HOH F 6 . ? 56.224 91.057 -26.095 1.00 21.22 ? 2345 HOH A O 1 HETATM 8558 O O . HOH F 6 . ? 39.086 83.360 -27.514 1.00 22.49 ? 2346 HOH A O 1 HETATM 8559 O O . HOH F 6 . ? 60.671 56.947 15.878 1.00 26.97 ? 2347 HOH A O 1 HETATM 8560 O O . HOH F 6 . ? 13.355 51.519 21.551 1.00 20.10 ? 2348 HOH A O 1 HETATM 8561 O O . HOH F 6 . ? 43.298 93.861 -37.850 1.00 18.90 ? 2349 HOH A O 1 HETATM 8562 O O . HOH F 6 . ? 28.019 35.463 -6.772 1.00 24.69 ? 2350 HOH A O 1 HETATM 8563 O O . HOH F 6 . ? 80.368 64.159 -21.483 1.00 23.24 ? 2351 HOH A O 1 HETATM 8564 O O . HOH F 6 . ? 51.321 45.313 9.554 1.00 33.63 ? 2352 HOH A O 1 HETATM 8565 O O . HOH F 6 . ? 20.817 46.727 -17.251 1.00 26.53 ? 2353 HOH A O 1 HETATM 8566 O O . HOH F 6 . ? 47.440 71.796 -20.450 1.00 22.76 ? 2354 HOH A O 1 HETATM 8567 O O . HOH F 6 . ? 21.567 86.160 -30.707 1.00 27.50 ? 2355 HOH A O 1 HETATM 8568 O O . HOH F 6 . ? 32.906 67.016 21.306 1.00 20.62 ? 2356 HOH A O 1 HETATM 8569 O O . HOH F 6 . ? 14.678 62.024 -14.550 1.00 20.12 ? 2357 HOH A O 1 HETATM 8570 O O . HOH F 6 . ? 50.367 73.662 -25.323 1.00 22.51 ? 2358 HOH A O 1 HETATM 8571 O O . HOH F 6 . ? 41.984 79.532 -23.857 1.00 28.31 ? 2359 HOH A O 1 HETATM 8572 O O . HOH F 6 . ? 39.944 45.302 25.612 1.00 30.28 ? 2360 HOH A O 1 HETATM 8573 O O . HOH F 6 . ? 50.731 76.634 14.388 1.00 23.00 ? 2361 HOH A O 1 HETATM 8574 O O . HOH F 6 . ? 38.526 45.080 -33.614 1.00 20.16 ? 2362 HOH A O 1 HETATM 8575 O O . HOH F 6 . ? 61.397 54.248 -29.114 1.00 21.00 ? 2363 HOH A O 1 HETATM 8576 O O . HOH F 6 . ? 53.595 46.874 23.497 1.00 29.79 ? 2364 HOH A O 1 HETATM 8577 O O . HOH F 6 . ? 57.016 43.264 -20.003 1.00 20.06 ? 2365 HOH A O 1 HETATM 8578 O O . HOH F 6 . ? 67.605 54.801 -18.415 1.00 18.68 ? 2366 HOH A O 1 HETATM 8579 O O . HOH F 6 . ? 42.233 79.908 -31.884 1.00 40.75 ? 2367 HOH A O 1 HETATM 8580 O O . HOH F 6 . ? 28.961 62.354 -39.813 1.00 22.33 ? 2368 HOH A O 1 HETATM 8581 O O . HOH F 6 . ? 27.142 61.379 10.362 1.00 35.96 ? 2369 HOH A O 1 HETATM 8582 O O . HOH F 6 . ? 45.749 45.205 23.064 1.00 24.76 ? 2370 HOH A O 1 HETATM 8583 O O . HOH F 6 . ? 34.952 51.374 35.826 1.00 31.05 ? 2371 HOH A O 1 HETATM 8584 O O . HOH F 6 . ? 57.699 62.460 7.789 1.00 32.79 ? 2372 HOH A O 1 HETATM 8585 O O . HOH F 6 . ? 25.218 33.483 13.285 1.00 29.46 ? 2373 HOH A O 1 HETATM 8586 O O . HOH F 6 . ? 27.341 59.395 8.541 1.00 13.77 ? 2374 HOH A O 1 HETATM 8587 O O . HOH F 6 . ? 42.213 94.550 -29.799 1.00 34.99 ? 2375 HOH A O 1 HETATM 8588 O O . HOH F 6 . ? 13.850 58.120 -1.426 1.00 17.93 ? 2376 HOH A O 1 HETATM 8589 O O . HOH F 6 . ? 49.365 76.450 5.168 1.00 32.03 ? 2377 HOH A O 1 HETATM 8590 O O . HOH F 6 . ? 27.589 67.671 28.163 1.00 22.58 ? 2378 HOH A O 1 HETATM 8591 O O . HOH F 6 . ? 41.846 39.471 16.348 1.00 31.31 ? 2379 HOH A O 1 HETATM 8592 O O . HOH F 6 . ? 58.778 46.371 -1.457 1.00 21.75 ? 2380 HOH A O 1 HETATM 8593 O O . HOH F 6 . ? 73.505 76.982 -18.707 1.00 29.78 ? 2381 HOH A O 1 HETATM 8594 O O . HOH F 6 . ? 19.553 39.310 17.460 1.00 13.63 ? 2382 HOH A O 1 HETATM 8595 O O . HOH F 6 . ? 39.580 58.985 -18.105 1.00 15.87 ? 2383 HOH A O 1 HETATM 8596 O O . HOH F 6 . ? 28.079 47.025 -31.417 1.00 24.28 ? 2384 HOH A O 1 HETATM 8597 O O . HOH F 6 . ? 68.549 47.024 -16.874 1.00 25.70 ? 2385 HOH A O 1 HETATM 8598 O O . HOH F 6 . ? 66.421 62.798 -13.610 1.00 21.06 ? 2386 HOH A O 1 HETATM 8599 O O . HOH F 6 . ? 26.668 75.202 1.990 1.00 19.96 ? 2387 HOH A O 1 HETATM 8600 O O . HOH F 6 . ? 40.113 39.297 9.176 1.00 23.70 ? 2388 HOH A O 1 HETATM 8601 O O . HOH F 6 . ? 20.936 47.612 38.777 1.00 30.38 ? 2389 HOH A O 1 HETATM 8602 O O . HOH F 6 . ? 42.028 74.865 -41.506 1.00 25.91 ? 2390 HOH A O 1 HETATM 8603 O O . HOH F 6 . ? 14.327 55.967 27.129 1.00 28.08 ? 2391 HOH A O 1 HETATM 8604 O O . HOH F 6 . ? 28.642 59.731 -39.333 1.00 29.52 ? 2392 HOH A O 1 HETATM 8605 O O . HOH F 6 . ? 39.119 43.186 22.671 1.00 29.19 ? 2393 HOH A O 1 HETATM 8606 O O . HOH F 6 . ? 16.445 52.795 -22.551 1.00 30.14 ? 2394 HOH A O 1 HETATM 8607 O O . HOH F 6 . ? 27.145 35.086 29.394 1.00 23.65 ? 2395 HOH A O 1 HETATM 8608 O O . HOH F 6 . ? 17.440 80.665 -7.322 1.00 24.34 ? 2396 HOH A O 1 HETATM 8609 O O . HOH F 6 . ? 48.187 41.863 3.631 1.00 23.08 ? 2397 HOH A O 1 HETATM 8610 O O . HOH F 6 . ? 73.599 51.474 -11.357 1.00 32.84 ? 2398 HOH A O 1 HETATM 8611 O O . HOH F 6 . ? 58.734 53.703 -22.381 1.00 19.11 ? 2399 HOH A O 1 HETATM 8612 O O . HOH F 6 . ? 47.543 79.631 -18.519 1.00 24.16 ? 2400 HOH A O 1 HETATM 8613 O O . HOH F 6 . ? 40.933 96.380 -37.436 1.00 26.47 ? 2401 HOH A O 1 HETATM 8614 O O . HOH F 6 . ? 61.073 63.717 15.327 1.00 19.24 ? 2402 HOH A O 1 HETATM 8615 O O . HOH F 6 . ? 59.453 37.728 -15.334 1.00 34.81 ? 2403 HOH A O 1 HETATM 8616 O O . HOH F 6 . ? 21.021 30.260 17.702 1.00 45.16 ? 2404 HOH A O 1 HETATM 8617 O O . HOH F 6 . ? 46.170 97.126 -44.073 1.00 30.36 ? 2405 HOH A O 1 HETATM 8618 O O . HOH F 6 . ? 21.432 86.298 -19.262 1.00 28.42 ? 2406 HOH A O 1 HETATM 8619 O O . HOH F 6 . ? 20.444 68.332 22.274 1.00 20.16 ? 2407 HOH A O 1 HETATM 8620 O O . HOH F 6 . ? 45.392 69.769 -17.975 1.00 26.97 ? 2408 HOH A O 1 HETATM 8621 O O . HOH F 6 . ? 16.198 70.531 6.144 1.00 35.24 ? 2409 HOH A O 1 HETATM 8622 O O . HOH F 6 . ? 51.142 52.840 -28.768 1.00 20.10 ? 2410 HOH A O 1 HETATM 8623 O O . HOH F 6 . ? 19.160 83.618 -25.683 1.00 29.32 ? 2411 HOH A O 1 HETATM 8624 O O . HOH F 6 . ? 40.016 86.141 -22.005 1.00 30.40 ? 2412 HOH A O 1 HETATM 8625 O O . HOH F 6 . ? 22.413 66.730 28.952 1.00 33.24 ? 2413 HOH A O 1 HETATM 8626 O O . HOH F 6 . ? 24.999 59.204 -36.546 1.00 37.81 ? 2414 HOH A O 1 HETATM 8627 O O . HOH F 6 . ? 58.274 34.823 -5.869 1.00 28.58 ? 2415 HOH A O 1 HETATM 8628 O O . HOH F 6 . ? 50.377 79.083 -15.846 1.00 26.37 ? 2416 HOH A O 1 HETATM 8629 O O . HOH F 6 . ? 51.045 95.824 -26.029 1.00 45.67 ? 2417 HOH A O 1 HETATM 8630 O O . HOH F 6 . ? 56.367 92.879 -29.740 1.00 26.35 ? 2418 HOH A O 1 HETATM 8631 O O . HOH F 6 . ? 52.586 73.171 4.231 1.00 31.01 ? 2419 HOH A O 1 HETATM 8632 O O . HOH F 6 . ? 21.954 36.804 0.028 1.00 27.60 ? 2420 HOH A O 1 HETATM 8633 O O . HOH F 6 . ? 10.791 77.283 -5.327 1.00 22.71 ? 2421 HOH A O 1 HETATM 8634 O O . HOH F 6 . ? 72.734 64.074 -21.215 1.00 26.85 ? 2422 HOH A O 1 HETATM 8635 O O . HOH F 6 . ? 79.953 73.951 -17.694 1.00 36.80 ? 2423 HOH A O 1 HETATM 8636 O O . HOH F 6 . ? 66.777 74.640 -4.545 1.00 20.19 ? 2424 HOH A O 1 HETATM 8637 O O . HOH F 6 . ? 48.141 64.296 -28.621 1.00 20.19 ? 2425 HOH A O 1 HETATM 8638 O O . HOH F 6 . ? 42.483 39.295 -1.716 1.00 25.01 ? 2426 HOH A O 1 HETATM 8639 O O . HOH F 6 . ? 63.185 67.885 -31.923 1.00 28.02 ? 2427 HOH A O 1 HETATM 8640 O O . HOH F 6 . ? 24.158 42.088 -14.634 1.00 25.22 ? 2428 HOH A O 1 HETATM 8641 O O . HOH F 6 . ? 27.557 50.869 13.294 1.00 15.71 ? 2429 HOH A O 1 HETATM 8642 O O . HOH F 6 . ? 38.671 83.630 -39.891 1.00 36.19 ? 2430 HOH A O 1 HETATM 8643 O O . HOH F 6 . ? 76.605 74.080 -26.904 1.00 20.77 ? 2431 HOH A O 1 HETATM 8644 O O . HOH F 6 . ? 28.822 72.373 22.400 1.00 24.48 ? 2432 HOH A O 1 HETATM 8645 O O . HOH F 6 . ? 20.915 55.116 -35.739 1.00 31.89 ? 2433 HOH A O 1 HETATM 8646 O O . HOH F 6 . ? 23.940 57.537 38.985 1.00 30.30 ? 2434 HOH A O 1 HETATM 8647 O O . HOH F 6 . ? 23.533 82.505 -40.816 1.00 21.57 ? 2435 HOH A O 1 HETATM 8648 O O . HOH F 6 . ? 17.164 67.139 -25.824 1.00 31.07 ? 2436 HOH A O 1 HETATM 8649 O O . HOH F 6 . ? 65.971 84.748 -22.387 1.00 47.47 ? 2437 HOH A O 1 HETATM 8650 O O . HOH F 6 . ? 20.663 67.996 8.366 1.00 20.35 ? 2438 HOH A O 1 HETATM 8651 O O . HOH F 6 . ? 61.495 63.834 -31.244 1.00 35.85 ? 2439 HOH A O 1 HETATM 8652 O O . HOH F 6 . ? 9.913 59.962 6.805 1.00 43.68 ? 2440 HOH A O 1 HETATM 8653 O O . HOH F 6 . ? 31.669 85.967 -19.881 1.00 32.07 ? 2441 HOH A O 1 HETATM 8654 O O . HOH F 6 . ? 28.452 87.845 -41.694 1.00 30.04 ? 2442 HOH A O 1 HETATM 8655 O O . HOH F 6 . ? 44.780 82.531 -30.505 1.00 26.19 ? 2443 HOH A O 1 HETATM 8656 O O . HOH F 6 . ? 59.307 67.168 -34.624 1.00 31.57 ? 2444 HOH A O 1 HETATM 8657 O O . HOH F 6 . ? 70.207 56.363 -12.767 1.00 32.43 ? 2445 HOH A O 1 HETATM 8658 O O . HOH F 6 . ? 46.047 46.106 16.275 1.00 37.58 ? 2446 HOH A O 1 HETATM 8659 O O . HOH F 6 . ? 45.845 82.859 -25.486 1.00 30.07 ? 2447 HOH A O 1 HETATM 8660 O O . HOH F 6 . ? 57.029 87.600 -20.194 1.00 36.49 ? 2448 HOH A O 1 HETATM 8661 O O . HOH F 6 . ? 73.683 74.272 -5.870 1.00 21.14 ? 2449 HOH A O 1 HETATM 8662 O O . HOH F 6 . ? 19.892 43.412 33.983 1.00 30.04 ? 2450 HOH A O 1 HETATM 8663 O O . HOH F 6 . ? 79.146 51.242 -0.830 1.00 26.10 ? 2451 HOH A O 1 HETATM 8664 O O . HOH F 6 . ? 65.936 45.558 -3.395 1.00 22.67 ? 2452 HOH A O 1 HETATM 8665 O O . HOH F 6 . ? 48.349 77.684 -9.876 1.00 29.22 ? 2453 HOH A O 1 HETATM 8666 O O . HOH F 6 . ? 29.705 34.089 -1.567 1.00 31.27 ? 2454 HOH A O 1 HETATM 8667 O O . HOH F 6 . ? 16.140 74.869 -24.121 1.00 40.77 ? 2455 HOH A O 1 HETATM 8668 O O . HOH F 6 . ? 22.456 31.207 29.253 1.00 35.11 ? 2456 HOH A O 1 HETATM 8669 O O . HOH F 6 . ? 33.461 84.263 -18.385 1.00 16.80 ? 2457 HOH A O 1 HETATM 8670 O O . HOH F 6 . ? 41.290 94.845 -39.636 1.00 22.45 ? 2458 HOH A O 1 HETATM 8671 O O . HOH F 6 . ? 44.236 83.783 -27.709 1.00 21.79 ? 2459 HOH A O 1 HETATM 8672 O O . HOH F 6 . ? 30.875 57.318 4.532 1.00 16.08 ? 2460 HOH A O 1 HETATM 8673 O O . HOH F 6 . ? 66.032 66.282 -0.599 1.00 21.71 ? 2461 HOH A O 1 HETATM 8674 O O . HOH F 6 . ? 46.448 68.252 26.284 1.00 41.38 ? 2462 HOH A O 1 HETATM 8675 O O . HOH F 6 . ? 70.100 61.849 -20.861 1.00 29.23 ? 2463 HOH A O 1 HETATM 8676 O O . HOH F 6 . ? 23.589 90.896 -25.957 1.00 35.06 ? 2464 HOH A O 1 HETATM 8677 O O . HOH F 6 . ? 25.142 71.204 22.279 1.00 37.31 ? 2465 HOH A O 1 HETATM 8678 O O . HOH F 6 . ? 48.415 95.173 -26.976 1.00 25.07 ? 2466 HOH A O 1 HETATM 8679 O O . HOH F 6 . ? 62.117 80.859 -19.072 1.00 25.18 ? 2467 HOH A O 1 HETATM 8680 O O . HOH F 6 . ? 27.517 47.394 45.791 1.00 39.52 ? 2468 HOH A O 1 HETATM 8681 O O . HOH F 6 . ? 24.432 34.361 0.145 1.00 44.39 ? 2469 HOH A O 1 HETATM 8682 O O . HOH F 6 . ? 58.262 68.145 13.319 1.00 48.11 ? 2470 HOH A O 1 HETATM 8683 O O . HOH F 6 . ? 7.985 48.025 11.779 1.00 22.81 ? 2471 HOH A O 1 HETATM 8684 O O . HOH F 6 . ? 71.296 59.563 0.832 1.00 44.02 ? 2472 HOH A O 1 HETATM 8685 O O . HOH F 6 . ? 67.582 88.024 -23.493 1.00 26.32 ? 2473 HOH A O 1 HETATM 8686 O O . HOH F 6 . ? 12.221 75.190 -13.708 1.00 28.32 ? 2474 HOH A O 1 HETATM 8687 O O . HOH F 6 . ? 27.797 51.963 42.487 1.00 22.78 ? 2475 HOH A O 1 HETATM 8688 O O . HOH F 6 . ? 21.978 62.928 33.544 1.00 28.11 ? 2476 HOH A O 1 HETATM 8689 O O . HOH F 6 . ? 34.297 87.318 -10.525 1.00 27.81 ? 2477 HOH A O 1 HETATM 8690 O O . HOH F 6 . ? 30.065 36.739 29.086 1.00 28.02 ? 2478 HOH A O 1 HETATM 8691 O O . HOH F 6 . ? 8.679 49.601 5.661 1.00 49.91 ? 2479 HOH A O 1 HETATM 8692 O O . HOH F 6 . ? 42.253 67.137 29.079 1.00 29.39 ? 2480 HOH A O 1 HETATM 8693 O O . HOH F 6 . ? 72.482 75.944 -27.195 1.00 41.79 ? 2481 HOH A O 1 HETATM 8694 O O . HOH F 6 . ? 8.883 44.540 12.811 1.00 32.42 ? 2482 HOH A O 1 HETATM 8695 O O . HOH F 6 . ? 71.027 43.052 -15.330 1.00 30.19 ? 2483 HOH A O 1 HETATM 8696 O O . HOH F 6 . ? 41.598 44.794 -24.464 1.00 31.02 ? 2484 HOH A O 1 HETATM 8697 O O . HOH F 6 . ? 40.070 66.790 31.279 1.00 42.29 ? 2485 HOH A O 1 HETATM 8698 O O . HOH F 6 . ? 53.149 52.689 26.009 1.00 23.20 ? 2486 HOH A O 1 HETATM 8699 O O . HOH F 6 . ? 26.182 44.217 -27.173 1.00 44.24 ? 2487 HOH A O 1 HETATM 8700 O O . HOH F 6 . ? 19.423 52.510 -27.037 1.00 35.23 ? 2488 HOH A O 1 HETATM 8701 O O . HOH F 6 . ? 70.677 95.725 -34.877 1.00 43.10 ? 2489 HOH A O 1 HETATM 8702 O O . HOH F 6 . ? 48.044 64.683 -25.765 1.00 23.34 ? 2490 HOH A O 1 HETATM 8703 O O . HOH F 6 . ? 17.686 53.054 35.441 1.00 22.35 ? 2491 HOH A O 1 HETATM 8704 O O . HOH F 6 . ? 83.523 70.174 -20.352 1.00 25.34 ? 2492 HOH A O 1 HETATM 8705 O O . HOH F 6 . ? 43.803 79.534 -42.684 1.00 34.77 ? 2493 HOH A O 1 HETATM 8706 O O . HOH F 6 . ? 22.545 62.607 16.405 1.00 24.72 ? 2494 HOH A O 1 HETATM 8707 O O . HOH F 6 . ? 45.871 79.350 -8.198 1.00 26.47 ? 2495 HOH A O 1 HETATM 8708 O O . HOH F 6 . ? 38.787 42.028 -22.262 1.00 31.68 ? 2496 HOH A O 1 HETATM 8709 O O . HOH F 6 . ? 36.915 29.422 13.027 1.00 33.93 ? 2497 HOH A O 1 HETATM 8710 O O . HOH F 6 . ? 20.449 65.432 27.404 1.00 33.00 ? 2498 HOH A O 1 HETATM 8711 O O . HOH F 6 . ? 61.338 77.440 -13.065 1.00 21.61 ? 2499 HOH A O 1 HETATM 8712 O O . HOH F 6 . ? 27.880 49.382 38.504 1.00 24.11 ? 2500 HOH A O 1 HETATM 8713 O O . HOH F 6 . ? 29.142 40.957 -25.658 1.00 30.25 ? 2501 HOH A O 1 HETATM 8714 O O . HOH F 6 . ? 43.448 41.908 -7.618 1.00 26.40 ? 2502 HOH A O 1 HETATM 8715 O O . HOH F 6 . ? 48.925 55.130 -22.545 1.00 22.02 ? 2503 HOH A O 1 HETATM 8716 O O . HOH F 6 . ? 35.658 38.911 -16.103 1.00 27.98 ? 2504 HOH A O 1 HETATM 8717 O O . HOH F 6 . ? 58.561 51.371 22.357 1.00 24.59 ? 2505 HOH A O 1 HETATM 8718 O O . HOH F 6 . ? 46.451 80.349 -42.703 1.00 32.28 ? 2506 HOH A O 1 HETATM 8719 O O . HOH F 6 . ? 71.630 84.538 -20.203 1.00 30.12 ? 2507 HOH A O 1 HETATM 8720 O O . HOH F 6 . ? 61.308 67.500 -36.512 1.00 41.19 ? 2508 HOH A O 1 HETATM 8721 O O . HOH F 6 . ? 58.177 34.955 -12.059 1.00 36.30 ? 2509 HOH A O 1 HETATM 8722 O O . HOH F 6 . ? 21.015 79.676 -23.564 1.00 22.65 ? 2510 HOH A O 1 HETATM 8723 O O . HOH F 6 . ? 51.189 71.415 -20.342 1.00 20.30 ? 2511 HOH A O 1 HETATM 8724 O O . HOH F 6 . ? 32.266 85.230 -8.729 1.00 32.05 ? 2512 HOH A O 1 HETATM 8725 O O . HOH F 6 . ? 21.612 29.248 27.806 1.00 27.91 ? 2513 HOH A O 1 HETATM 8726 O O . HOH F 6 . ? 31.620 57.485 37.464 1.00 21.92 ? 2514 HOH A O 1 HETATM 8727 O O . HOH F 6 . ? 17.595 81.426 -17.391 1.00 43.76 ? 2515 HOH A O 1 HETATM 8728 O O . HOH F 6 . ? 22.159 80.051 -36.142 1.00 30.08 ? 2516 HOH A O 1 HETATM 8729 O O . HOH F 6 . ? 25.403 73.952 8.742 1.00 24.41 ? 2517 HOH A O 1 HETATM 8730 O O . HOH F 6 . ? 22.024 79.961 5.462 1.00 24.99 ? 2518 HOH A O 1 HETATM 8731 O O . HOH F 6 . ? 39.935 38.970 -3.504 1.00 28.48 ? 2519 HOH A O 1 HETATM 8732 O O . HOH F 6 . ? 36.915 34.979 -15.998 1.00 30.00 ? 2520 HOH A O 1 HETATM 8733 O O . HOH F 6 . ? 34.751 45.925 33.368 1.00 16.20 ? 2521 HOH A O 1 HETATM 8734 O O . HOH F 6 . ? 69.832 62.208 0.018 1.00 34.68 ? 2522 HOH A O 1 HETATM 8735 O O . HOH F 6 . ? 46.405 74.535 22.337 1.00 32.88 ? 2523 HOH A O 1 HETATM 8736 O O . HOH F 6 . ? 60.256 92.124 -28.878 1.00 22.01 ? 2524 HOH A O 1 HETATM 8737 O O . HOH F 6 . ? 37.993 62.216 35.255 1.00 31.33 ? 2525 HOH A O 1 HETATM 8738 O O . HOH F 6 . ? 62.056 83.071 -38.314 1.00 34.06 ? 2526 HOH A O 1 HETATM 8739 O O . HOH F 6 . ? 62.974 42.974 -21.049 1.00 30.43 ? 2527 HOH A O 1 HETATM 8740 O O . HOH F 6 . ? 53.147 44.737 22.696 1.00 33.16 ? 2528 HOH A O 1 HETATM 8741 O O . HOH F 6 . ? 30.820 34.737 -9.403 1.00 32.27 ? 2529 HOH A O 1 HETATM 8742 O O . HOH F 6 . ? 29.543 31.659 21.874 1.00 39.91 ? 2530 HOH A O 1 HETATM 8743 O O . HOH F 6 . ? 78.459 68.908 -12.238 1.00 27.45 ? 2531 HOH A O 1 HETATM 8744 O O . HOH F 6 . ? 31.091 69.344 -45.463 1.00 34.12 ? 2532 HOH A O 1 HETATM 8745 O O . HOH F 6 . ? 73.237 82.322 -21.568 1.00 24.93 ? 2533 HOH A O 1 HETATM 8746 O O . HOH F 6 . ? 20.421 37.835 12.043 1.00 31.17 ? 2534 HOH A O 1 HETATM 8747 O O . HOH F 6 . ? 35.236 95.101 -32.553 1.00 27.46 ? 2535 HOH A O 1 HETATM 8748 O O . HOH F 6 . ? 20.601 80.377 -33.869 1.00 38.40 ? 2536 HOH A O 1 HETATM 8749 O O . HOH F 6 . ? 49.247 91.805 -24.765 1.00 29.91 ? 2537 HOH A O 1 HETATM 8750 O O . HOH F 6 . ? 43.890 44.885 19.333 1.00 33.13 ? 2538 HOH A O 1 HETATM 8751 O O . HOH F 6 . ? 21.092 35.894 -4.805 1.00 40.42 ? 2539 HOH A O 1 HETATM 8752 O O . HOH F 6 . ? 71.211 62.997 -27.359 1.00 38.81 ? 2540 HOH A O 1 HETATM 8753 O O . HOH F 6 . ? 19.961 35.455 25.756 1.00 24.26 ? 2541 HOH A O 1 HETATM 8754 O O . HOH F 6 . ? 59.267 86.628 -46.083 1.00 35.45 ? 2542 HOH A O 1 HETATM 8755 O O . HOH F 6 . ? 28.625 69.644 -39.560 1.00 30.46 ? 2543 HOH A O 1 HETATM 8756 O O . HOH F 6 . ? 45.609 83.334 -43.427 1.00 45.73 ? 2544 HOH A O 1 HETATM 8757 O O . HOH F 6 . ? 29.713 81.970 -42.755 1.00 48.46 ? 2545 HOH A O 1 HETATM 8758 O O . HOH F 6 . ? 28.350 90.735 -42.723 1.00 34.12 ? 2546 HOH A O 1 HETATM 8759 O O . HOH F 6 . ? 20.894 41.455 34.998 1.00 38.75 ? 2547 HOH A O 1 HETATM 8760 O O . HOH F 6 . ? 39.533 31.004 12.812 1.00 52.72 ? 2548 HOH A O 1 HETATM 8761 O O . HOH F 6 . ? 62.171 85.484 -23.185 1.00 28.22 ? 2549 HOH A O 1 HETATM 8762 O O . HOH F 6 . ? 31.080 68.408 13.955 1.00 34.01 ? 2550 HOH A O 1 HETATM 8763 O O . HOH F 6 . ? 14.908 63.770 -25.673 1.00 27.86 ? 2551 HOH A O 1 HETATM 8764 O O . HOH F 6 . ? 29.795 72.424 12.323 1.00 19.67 ? 2552 HOH A O 1 HETATM 8765 O O . HOH F 6 . ? 60.630 93.254 -38.086 1.00 43.33 ? 2553 HOH A O 1 HETATM 8766 O O . HOH F 6 . ? 59.121 62.126 25.890 1.00 23.45 ? 2554 HOH A O 1 HETATM 8767 O O . HOH F 6 . ? 51.239 79.529 -1.589 1.00 40.32 ? 2555 HOH A O 1 HETATM 8768 O O . HOH F 6 . ? 59.429 91.172 -35.481 1.00 28.64 ? 2556 HOH A O 1 HETATM 8769 O O . HOH F 6 . ? 24.275 60.835 35.949 1.00 46.00 ? 2557 HOH A O 1 HETATM 8770 O O . HOH F 6 . ? 11.304 61.813 0.137 1.00 38.18 ? 2558 HOH A O 1 HETATM 8771 O O . HOH F 6 . ? 55.210 80.464 -19.529 1.00 23.12 ? 2559 HOH A O 1 HETATM 8772 O O . HOH F 6 . ? 40.837 40.452 -21.510 1.00 28.69 ? 2560 HOH A O 1 HETATM 8773 O O . HOH F 6 . ? 39.989 35.569 11.322 1.00 26.01 ? 2561 HOH A O 1 HETATM 8774 O O . HOH F 6 . ? 64.776 79.998 -9.085 1.00 40.61 ? 2562 HOH A O 1 HETATM 8775 O O . HOH F 6 . ? 73.169 43.901 -12.437 1.00 45.88 ? 2563 HOH A O 1 HETATM 8776 O O . HOH F 6 . ? 12.991 74.691 -19.126 1.00 33.60 ? 2564 HOH A O 1 HETATM 8777 O O . HOH F 6 . ? 57.334 75.744 -2.961 1.00 26.38 ? 2565 HOH A O 1 HETATM 8778 O O . HOH F 6 . ? 22.839 37.084 13.362 1.00 32.22 ? 2566 HOH A O 1 HETATM 8779 O O . HOH F 6 . ? 29.378 88.707 -26.251 1.00 10.06 ? 2567 HOH A O 1 HETATM 8780 O O . HOH F 6 . ? 37.288 33.793 5.904 1.00 40.97 ? 2568 HOH A O 1 HETATM 8781 O O . HOH F 6 . ? 34.094 70.529 -44.861 1.00 36.57 ? 2569 HOH A O 1 HETATM 8782 O O . HOH F 6 . ? 64.475 77.451 0.306 1.00 45.11 ? 2570 HOH A O 1 HETATM 8783 O O . HOH F 6 . ? 30.820 51.643 39.730 1.00 45.66 ? 2571 HOH A O 1 HETATM 8784 O O . HOH F 6 . ? 14.712 50.386 0.707 1.00 38.19 ? 2572 HOH A O 1 HETATM 8785 O O . HOH F 6 . ? 67.081 81.354 -11.472 1.00 27.78 ? 2573 HOH A O 1 HETATM 8786 O O . HOH F 6 . ? 43.621 56.941 33.439 1.00 21.34 ? 2574 HOH A O 1 HETATM 8787 O O . HOH F 6 . ? 56.407 50.090 -30.323 1.00 40.17 ? 2575 HOH A O 1 HETATM 8788 O O . HOH F 6 . ? 63.263 57.766 26.284 1.00 39.25 ? 2576 HOH A O 1 HETATM 8789 O O . HOH F 6 . ? 62.293 48.244 -21.125 1.00 40.91 ? 2577 HOH A O 1 HETATM 8790 O O . HOH F 6 . ? 26.681 91.737 -27.594 1.00 28.62 ? 2578 HOH A O 1 HETATM 8791 O O . HOH F 6 . ? 13.562 70.057 -9.784 1.00 31.80 ? 2579 HOH A O 1 HETATM 8792 O O . HOH F 6 . ? 60.526 78.770 -41.763 1.00 29.73 ? 2580 HOH A O 1 HETATM 8793 O O . HOH F 6 . ? 36.400 62.665 -38.475 1.00 31.90 ? 2581 HOH A O 1 HETATM 8794 O O . HOH F 6 . ? 37.647 80.558 -0.721 1.00 20.20 ? 2582 HOH A O 1 HETATM 8795 O O . HOH F 6 . ? 48.686 97.809 -34.090 1.00 26.27 ? 2583 HOH A O 1 HETATM 8796 O O . HOH F 6 . ? 60.444 73.283 -0.208 1.00 38.16 ? 2584 HOH A O 1 HETATM 8797 O O . HOH F 6 . ? 41.161 48.292 -29.459 1.00 46.35 ? 2585 HOH A O 1 HETATM 8798 O O . HOH F 6 . ? 63.270 52.034 -0.595 1.00 27.40 ? 2586 HOH A O 1 HETATM 8799 O O . HOH F 6 . ? 23.136 48.752 -36.126 1.00 36.23 ? 2587 HOH A O 1 HETATM 8800 O O . HOH F 6 . ? 18.315 70.957 -29.712 1.00 33.65 ? 2588 HOH A O 1 HETATM 8801 O O . HOH F 6 . ? 27.341 50.210 23.298 1.00 38.02 ? 2589 HOH A O 1 HETATM 8802 O O . HOH F 6 . ? 59.837 52.817 -30.666 1.00 32.82 ? 2590 HOH A O 1 HETATM 8803 O O . HOH F 6 . ? 33.867 47.740 36.362 1.00 40.21 ? 2591 HOH A O 1 HETATM 8804 O O . HOH F 6 . ? 27.322 82.044 3.058 1.00 22.74 ? 2592 HOH A O 1 HETATM 8805 O O . HOH F 6 . ? 53.117 71.214 -16.668 1.00 35.86 ? 2593 HOH A O 1 HETATM 8806 O O . HOH F 6 . ? 54.229 60.807 31.034 1.00 42.96 ? 2594 HOH A O 1 HETATM 8807 O O . HOH F 6 . ? 35.691 77.651 -43.240 1.00 37.91 ? 2595 HOH A O 1 HETATM 8808 O O . HOH F 6 . ? 61.001 45.416 -3.810 1.00 37.57 ? 2596 HOH A O 1 HETATM 8809 O O . HOH F 6 . ? 65.441 78.803 -5.851 1.00 23.91 ? 2597 HOH A O 1 HETATM 8810 O O . HOH F 6 . ? 49.580 50.828 32.482 1.00 21.73 ? 2598 HOH A O 1 HETATM 8811 O O . HOH F 6 . ? 17.442 45.864 -14.287 1.00 25.77 ? 2599 HOH A O 1 HETATM 8812 O O . HOH F 6 . ? 28.616 55.149 39.859 1.00 42.63 ? 2600 HOH A O 1 HETATM 8813 O O . HOH F 6 . ? 50.835 59.919 -9.051 1.00 8.39 ? 2601 HOH A O 1 HETATM 8814 O O . HOH F 6 . ? 43.823 63.095 -28.729 1.00 9.19 ? 2602 HOH A O 1 HETATM 8815 O O . HOH F 6 . ? 37.998 81.816 -31.536 1.00 10.96 ? 2603 HOH A O 1 HETATM 8816 O O . HOH F 6 . ? 32.364 39.187 -4.987 1.00 9.84 ? 2604 HOH A O 1 HETATM 8817 O O . HOH F 6 . ? 60.404 60.980 -18.268 1.00 10.82 ? 2605 HOH A O 1 HETATM 8818 O O . HOH F 6 . ? 63.238 58.619 -1.540 1.00 10.91 ? 2606 HOH A O 1 HETATM 8819 O O . HOH F 6 . ? 60.734 60.904 -3.644 1.00 11.67 ? 2607 HOH A O 1 HETATM 8820 O O . HOH F 6 . ? 46.807 74.493 7.606 1.00 10.78 ? 2608 HOH A O 1 HETATM 8821 O O . HOH F 6 . ? 54.972 57.500 -0.590 1.00 12.35 ? 2609 HOH A O 1 HETATM 8822 O O . HOH F 6 . ? 30.197 74.940 -29.344 1.00 13.94 ? 2610 HOH A O 1 HETATM 8823 O O . HOH F 6 . ? 58.918 56.766 -1.477 1.00 11.50 ? 2611 HOH A O 1 HETATM 8824 O O . HOH F 6 . ? 58.666 52.792 -0.110 1.00 14.27 ? 2612 HOH A O 1 HETATM 8825 O O . HOH F 6 . ? 63.159 61.130 -4.996 1.00 13.39 ? 2613 HOH A O 1 HETATM 8826 O O . HOH F 6 . ? 27.923 48.742 12.113 1.00 10.76 ? 2614 HOH A O 1 HETATM 8827 O O . HOH F 6 . ? 66.527 56.274 -20.320 1.00 13.53 ? 2615 HOH A O 1 HETATM 8828 O O . HOH F 6 . ? 19.830 46.863 -14.453 1.00 19.36 ? 2616 HOH A O 1 HETATM 8829 O O . HOH F 6 . ? 38.607 69.175 -38.238 1.00 13.06 ? 2617 HOH A O 1 HETATM 8830 O O . HOH F 6 . ? 33.701 60.368 23.362 1.00 20.79 ? 2618 HOH A O 1 HETATM 8831 O O . HOH F 6 . ? 39.686 55.909 3.031 1.00 10.45 ? 2619 HOH A O 1 HETATM 8832 O O . HOH F 6 . ? 24.600 61.449 9.248 1.00 18.06 ? 2620 HOH A O 1 HETATM 8833 O O . HOH F 6 . ? 16.739 57.167 12.946 1.00 16.41 ? 2621 HOH A O 1 HETATM 8834 O O . HOH F 6 . ? 39.417 69.209 -35.562 1.00 13.22 ? 2622 HOH A O 1 HETATM 8835 O O . HOH F 6 . ? 49.903 67.572 4.244 1.00 26.26 ? 2623 HOH A O 1 HETATM 8836 O O . HOH F 6 . ? 27.644 53.407 20.060 1.00 17.36 ? 2624 HOH A O 1 HETATM 8837 O O . HOH F 6 . ? 29.648 82.978 2.471 1.00 12.35 ? 2625 HOH A O 1 HETATM 8838 O O . HOH F 6 . ? 28.186 90.982 -25.411 1.00 18.43 ? 2626 HOH A O 1 HETATM 8839 O O . HOH F 6 . ? 46.095 77.687 9.474 1.00 11.79 ? 2627 HOH A O 1 HETATM 8840 O O . HOH F 6 . ? 12.560 49.309 17.619 1.00 18.54 ? 2628 HOH A O 1 HETATM 8841 O O . HOH F 6 . ? 12.357 68.564 -11.456 1.00 23.51 ? 2629 HOH A O 1 HETATM 8842 O O . HOH F 6 . ? 41.508 44.719 -6.901 1.00 18.54 ? 2630 HOH A O 1 HETATM 8843 O O . HOH F 6 . ? 45.551 67.790 -27.855 1.00 21.05 ? 2631 HOH A O 1 HETATM 8844 O O . HOH F 6 . ? 14.025 50.641 24.064 1.00 16.49 ? 2632 HOH A O 1 HETATM 8845 O O . HOH F 6 . ? 67.443 46.698 -1.535 1.00 21.76 ? 2633 HOH A O 1 HETATM 8846 O O . HOH F 6 . ? 8.984 50.433 8.024 1.00 25.02 ? 2634 HOH A O 1 HETATM 8847 O O . HOH F 6 . ? 48.447 41.001 -1.161 1.00 23.73 ? 2635 HOH A O 1 HETATM 8848 O O . HOH F 6 . ? 17.872 74.567 4.075 1.00 22.95 ? 2636 HOH A O 1 HETATM 8849 O O . HOH F 6 . ? 44.837 55.050 -18.301 1.00 13.82 ? 2637 HOH A O 1 HETATM 8850 O O . HOH F 6 . ? 83.287 66.538 -15.557 1.00 20.04 ? 2638 HOH A O 1 HETATM 8851 O O . HOH F 6 . ? 48.832 69.122 -36.936 1.00 23.22 ? 2639 HOH A O 1 HETATM 8852 O O . HOH F 6 . ? 51.713 70.211 -38.108 1.00 29.00 ? 2640 HOH A O 1 HETATM 8853 O O . HOH F 6 . ? 29.584 72.454 34.405 1.00 26.33 ? 2641 HOH A O 1 HETATM 8854 O O . HOH F 6 . ? 37.478 61.532 -32.551 1.00 27.52 ? 2642 HOH A O 1 HETATM 8855 O O . HOH F 6 . ? 57.218 48.980 21.387 1.00 22.69 ? 2643 HOH A O 1 HETATM 8856 O O . HOH F 6 . ? 42.937 59.484 -31.530 1.00 26.20 ? 2644 HOH A O 1 HETATM 8857 O O . HOH F 6 . ? 31.994 34.505 -3.167 1.00 23.67 ? 2645 HOH A O 1 HETATM 8858 O O . HOH F 6 . ? 36.954 59.090 -33.690 1.00 22.00 ? 2646 HOH A O 1 HETATM 8859 O O . HOH F 6 . ? 61.389 59.123 14.727 1.00 26.39 ? 2647 HOH A O 1 HETATM 8860 O O . HOH F 6 . ? 40.161 56.441 -19.082 1.00 28.48 ? 2648 HOH A O 1 HETATM 8861 O O . HOH F 6 . ? 61.672 76.490 -10.668 1.00 20.70 ? 2649 HOH A O 1 HETATM 8862 O O . HOH F 6 . ? 10.444 50.508 -11.268 1.00 48.59 ? 2650 HOH A O 1 HETATM 8863 O O . HOH F 6 . ? 37.595 51.579 -18.557 1.00 19.72 ? 2651 HOH A O 1 HETATM 8864 O O . HOH F 6 . ? 25.664 52.251 12.896 1.00 18.16 ? 2652 HOH A O 1 HETATM 8865 O O . HOH F 6 . ? 69.410 63.707 -28.933 1.00 25.92 ? 2653 HOH A O 1 HETATM 8866 O O . HOH F 6 . ? 72.854 66.567 -10.084 1.00 25.48 ? 2654 HOH A O 1 HETATM 8867 O O . HOH F 6 . ? 42.498 56.244 2.056 1.00 26.21 ? 2655 HOH A O 1 HETATM 8868 O O . HOH F 6 . ? 55.991 65.119 -36.231 1.00 19.11 ? 2656 HOH A O 1 HETATM 8869 O O . HOH F 6 . ? 17.824 66.252 27.925 1.00 20.09 ? 2657 HOH A O 1 HETATM 8870 O O . HOH F 6 . ? 11.693 63.674 -17.014 1.00 23.46 ? 2658 HOH A O 1 HETATM 8871 O O . HOH F 6 . ? 35.450 86.508 -18.156 1.00 25.45 ? 2659 HOH A O 1 HETATM 8872 O O . HOH F 6 . ? 9.955 60.271 -20.359 1.00 22.90 ? 2660 HOH A O 1 HETATM 8873 O O . HOH F 6 . ? 11.653 48.604 -2.557 1.00 27.69 ? 2661 HOH A O 1 HETATM 8874 O O . HOH F 6 . ? 39.902 52.957 36.233 1.00 32.13 ? 2662 HOH A O 1 HETATM 8875 O O . HOH F 6 . ? 49.753 47.496 28.923 1.00 23.67 ? 2663 HOH A O 1 HETATM 8876 O O . HOH F 6 . ? 24.126 34.590 15.234 1.00 26.92 ? 2664 HOH A O 1 HETATM 8877 O O . HOH F 6 . ? 59.285 51.070 24.921 1.00 26.01 ? 2665 HOH A O 1 HETATM 8878 O O . HOH F 6 . ? 38.028 83.082 -1.297 1.00 30.00 ? 2666 HOH A O 1 HETATM 8879 O O . HOH F 6 . ? 12.974 51.782 -12.375 1.00 31.53 ? 2667 HOH A O 1 HETATM 8880 O O . HOH F 6 . ? 48.231 50.725 35.185 1.00 39.26 ? 2668 HOH A O 1 HETATM 8881 O O . HOH F 6 . ? 48.127 41.405 -5.344 1.00 27.88 ? 2669 HOH A O 1 HETATM 8882 O O . HOH F 6 . ? 22.417 40.752 -11.301 1.00 34.05 ? 2670 HOH A O 1 HETATM 8883 O O . HOH F 6 . ? 16.148 36.486 16.476 1.00 22.56 ? 2671 HOH A O 1 HETATM 8884 O O . HOH F 6 . ? 22.341 68.172 20.444 1.00 25.19 ? 2672 HOH A O 1 HETATM 8885 O O . HOH F 6 . ? 72.040 47.041 -17.992 1.00 25.36 ? 2673 HOH A O 1 HETATM 8886 O O . HOH F 6 . ? 40.972 85.265 -12.049 1.00 21.29 ? 2674 HOH A O 1 HETATM 8887 O O . HOH F 6 . ? 57.107 46.912 15.895 1.00 24.33 ? 2675 HOH A O 1 HETATM 8888 O O . HOH F 6 . ? 51.687 64.201 24.584 1.00 19.55 ? 2676 HOH A O 1 HETATM 8889 O O . HOH F 6 . ? 56.684 58.611 1.268 1.00 30.03 ? 2677 HOH A O 1 HETATM 8890 O O . HOH F 6 . ? 57.676 58.448 5.448 1.00 35.99 ? 2678 HOH A O 1 HETATM 8891 O O . HOH F 6 . ? 74.625 64.629 -15.648 1.00 39.94 ? 2679 HOH A O 1 HETATM 8892 O O . HOH F 6 . ? 14.816 70.739 -22.970 1.00 22.66 ? 2680 HOH A O 1 HETATM 8893 O O . HOH F 6 . ? 13.052 52.165 -15.225 1.00 31.65 ? 2681 HOH A O 1 HETATM 8894 O O . HOH F 6 . ? 22.175 48.322 45.235 1.00 24.97 ? 2682 HOH A O 1 HETATM 8895 O O . HOH F 6 . ? 23.305 86.956 -32.686 1.00 32.66 ? 2683 HOH A O 1 HETATM 8896 O O . HOH F 6 . ? 66.632 81.709 -14.225 1.00 30.70 ? 2684 HOH A O 1 HETATM 8897 O O . HOH F 6 . ? 47.240 61.331 -29.052 1.00 20.50 ? 2685 HOH A O 1 HETATM 8898 O O . HOH F 6 . ? 52.680 70.876 5.510 1.00 33.14 ? 2686 HOH A O 1 HETATM 8899 O O . HOH F 6 . ? 40.806 55.778 -33.341 1.00 25.24 ? 2687 HOH A O 1 HETATM 8900 O O . HOH F 6 . ? 39.578 39.840 20.007 1.00 28.29 ? 2688 HOH A O 1 HETATM 8901 O O . HOH F 6 . ? 44.410 55.433 35.989 1.00 42.82 ? 2689 HOH A O 1 HETATM 8902 O O . HOH F 6 . ? 13.826 62.317 14.578 1.00 30.63 ? 2690 HOH A O 1 HETATM 8903 O O . HOH F 6 . ? 39.870 39.508 -0.075 1.00 33.80 ? 2691 HOH A O 1 HETATM 8904 O O . HOH F 6 . ? 31.332 70.745 22.169 1.00 45.64 ? 2692 HOH A O 1 HETATM 8905 O O . HOH F 6 . ? 27.063 41.623 -27.405 1.00 41.08 ? 2693 HOH A O 1 HETATM 8906 O O . HOH F 6 . ? 19.746 41.738 -5.052 1.00 27.31 ? 2694 HOH A O 1 HETATM 8907 O O . HOH F 6 . ? 13.527 61.175 7.442 1.00 46.69 ? 2695 HOH A O 1 HETATM 8908 O O . HOH F 6 . ? 46.785 46.026 11.582 1.00 29.12 ? 2696 HOH A O 1 HETATM 8909 O O . HOH F 6 . ? 42.895 68.497 -30.270 1.00 21.45 ? 2697 HOH A O 1 HETATM 8910 O O . HOH F 6 . ? 47.723 69.907 -16.695 1.00 28.51 ? 2698 HOH A O 1 HETATM 8911 O O . HOH F 6 . ? 58.468 93.583 -27.648 1.00 36.68 ? 2699 HOH A O 1 HETATM 8912 O O . HOH F 6 . ? 31.327 79.177 -42.789 1.00 26.75 ? 2700 HOH A O 1 HETATM 8913 O O . HOH F 6 . ? 22.260 42.657 -13.067 1.00 31.01 ? 2701 HOH A O 1 HETATM 8914 O O . HOH F 6 . ? 52.696 92.217 -23.489 1.00 34.87 ? 2702 HOH A O 1 HETATM 8915 O O . HOH F 6 . ? 59.936 51.060 20.372 1.00 25.85 ? 2703 HOH A O 1 HETATM 8916 O O . HOH F 6 . ? 14.609 51.215 32.466 1.00 25.58 ? 2704 HOH A O 1 HETATM 8917 O O . HOH F 6 . ? 26.572 66.991 19.467 1.00 33.07 ? 2705 HOH A O 1 HETATM 8918 O O . HOH F 6 . ? 11.994 41.655 19.905 1.00 30.79 ? 2706 HOH A O 1 HETATM 8919 O O . HOH F 6 . ? 69.288 77.034 -34.215 1.00 32.17 ? 2707 HOH A O 1 HETATM 8920 O O . HOH F 6 . ? 16.543 43.101 -2.535 1.00 23.52 ? 2708 HOH A O 1 HETATM 8921 O O . HOH F 6 . ? 34.335 66.249 -42.542 1.00 35.04 ? 2709 HOH A O 1 HETATM 8922 O O . HOH F 6 . ? 57.141 36.088 -14.178 1.00 31.14 ? 2710 HOH A O 1 HETATM 8923 O O . HOH F 6 . ? 37.201 37.512 2.926 1.00 26.26 ? 2711 HOH A O 1 HETATM 8924 O O . HOH F 6 . ? 51.294 66.563 8.417 1.00 27.10 ? 2712 HOH A O 1 HETATM 8925 O O . HOH F 6 . ? 10.469 51.269 21.158 1.00 31.01 ? 2713 HOH A O 1 HETATM 8926 O O . HOH F 6 . ? 30.316 87.307 -14.994 1.00 28.13 ? 2714 HOH A O 1 HETATM 8927 O O . HOH F 6 . ? 42.288 54.942 -17.328 1.00 33.25 ? 2715 HOH A O 1 HETATM 8928 O O . HOH F 6 . ? 29.619 75.705 10.979 1.00 18.55 ? 2716 HOH A O 1 HETATM 8929 O O . HOH F 6 . ? 43.158 98.264 -37.344 1.00 27.61 ? 2717 HOH A O 1 HETATM 8930 O O . HOH F 6 . ? 64.809 78.943 -1.679 1.00 29.66 ? 2718 HOH A O 1 HETATM 8931 O O . HOH F 6 . ? 43.286 40.384 -23.208 1.00 29.72 ? 2719 HOH A O 1 HETATM 8932 O O . HOH F 6 . ? 59.467 48.936 2.118 1.00 27.76 ? 2720 HOH A O 1 HETATM 8933 O O . HOH F 6 . ? 69.138 41.754 -17.119 1.00 31.62 ? 2721 HOH A O 1 HETATM 8934 O O . HOH F 6 . ? 24.515 71.893 -39.734 1.00 25.90 ? 2722 HOH A O 1 HETATM 8935 O O . HOH F 6 . ? 23.755 48.466 -24.330 1.00 37.92 ? 2723 HOH A O 1 HETATM 8936 O O . HOH F 6 . ? 47.103 68.027 -24.848 1.00 26.87 ? 2724 HOH A O 1 HETATM 8937 O O . HOH F 6 . ? 53.272 53.225 -30.094 1.00 31.96 ? 2725 HOH A O 1 HETATM 8938 O O . HOH F 6 . ? 24.902 34.290 35.664 1.00 38.05 ? 2726 HOH A O 1 HETATM 8939 O O . HOH F 6 . ? 12.973 52.323 25.753 1.00 30.52 ? 2727 HOH A O 1 HETATM 8940 O O . HOH F 6 . ? 51.606 44.423 2.842 1.00 25.25 ? 2728 HOH A O 1 HETATM 8941 O O . HOH F 6 . ? 21.827 55.264 40.203 1.00 34.49 ? 2729 HOH A O 1 HETATM 8942 O O . HOH F 6 . ? 64.122 70.704 -5.267 1.00 15.88 ? 2730 HOH A O 1 HETATM 8943 O O . HOH F 6 . ? 47.003 89.380 -23.162 1.00 45.71 ? 2731 HOH A O 1 HETATM 8944 O O . HOH F 6 . ? 7.998 53.049 -7.666 1.00 17.09 ? 2732 HOH A O 1 HETATM 8945 O O . HOH F 6 . ? 22.300 80.808 -42.612 1.00 29.55 ? 2733 HOH A O 1 HETATM 8946 O O . HOH F 6 . ? 63.683 65.448 -30.583 1.00 43.47 ? 2734 HOH A O 1 HETATM 8947 O O . HOH F 6 . ? 18.152 48.615 -19.730 1.00 28.53 ? 2735 HOH A O 1 HETATM 8948 O O . HOH F 6 . ? 59.635 76.838 -4.361 1.00 31.57 ? 2736 HOH A O 1 HETATM 8949 O O . HOH F 6 . ? 21.122 84.101 -12.465 1.00 25.88 ? 2737 HOH A O 1 HETATM 8950 O O . HOH F 6 . ? 19.015 52.698 -32.041 1.00 37.60 ? 2738 HOH A O 1 HETATM 8951 O O . HOH F 6 . ? 67.216 85.551 -36.273 1.00 35.91 ? 2739 HOH A O 1 HETATM 8952 O O . HOH F 6 . ? 64.044 89.692 -22.406 1.00 26.70 ? 2740 HOH A O 1 HETATM 8953 O O . HOH F 6 . ? 32.986 84.176 0.501 1.00 26.60 ? 2741 HOH A O 1 HETATM 8954 O O . HOH F 6 . ? 45.807 65.355 -28.638 1.00 27.51 ? 2742 HOH A O 1 HETATM 8955 O O . HOH F 6 . ? 12.886 62.085 -2.333 1.00 23.62 ? 2743 HOH A O 1 HETATM 8956 O O . HOH F 6 . ? 25.525 63.032 13.741 1.00 20.03 ? 2744 HOH A O 1 HETATM 8957 O O . HOH F 6 . ? 28.411 34.878 32.359 1.00 44.41 ? 2745 HOH A O 1 HETATM 8958 O O . HOH F 6 . ? 35.795 68.474 23.662 1.00 24.56 ? 2746 HOH A O 1 HETATM 8959 O O . HOH F 6 . ? 31.864 33.894 17.099 1.00 37.11 ? 2747 HOH A O 1 HETATM 8960 O O . HOH F 6 . ? 40.017 100.282 -32.029 1.00 35.94 ? 2748 HOH A O 1 HETATM 8961 O O . HOH F 6 . ? 54.044 82.990 -44.787 1.00 40.20 ? 2749 HOH A O 1 HETATM 8962 O O . HOH F 6 . ? 70.153 53.609 -10.495 1.00 35.38 ? 2750 HOH A O 1 HETATM 8963 O O . HOH F 6 . ? 12.490 64.768 -12.451 1.00 27.46 ? 2751 HOH A O 1 HETATM 8964 O O . HOH F 6 . ? 39.635 50.018 35.990 1.00 40.84 ? 2752 HOH A O 1 HETATM 8965 O O . HOH F 6 . ? 27.717 44.687 38.273 1.00 29.97 ? 2753 HOH A O 1 HETATM 8966 O O . HOH F 6 . ? 27.606 38.487 -22.541 1.00 45.89 ? 2754 HOH A O 1 HETATM 8967 O O . HOH F 6 . ? 72.193 95.638 -31.471 1.00 27.30 ? 2755 HOH A O 1 HETATM 8968 O O . HOH F 6 . ? 21.844 48.984 -39.312 1.00 43.32 ? 2756 HOH A O 1 HETATM 8969 O O . HOH F 6 . ? 20.697 31.675 31.423 1.00 43.99 ? 2757 HOH A O 1 HETATM 8970 O O . HOH F 6 . ? 43.068 47.598 -27.546 1.00 49.47 ? 2758 HOH A O 1 HETATM 8971 O O . HOH F 6 . ? 55.766 52.137 27.303 1.00 23.25 ? 2759 HOH A O 1 HETATM 8972 O O . HOH F 6 . ? 30.842 58.432 -40.432 1.00 40.67 ? 2760 HOH A O 1 HETATM 8973 O O . HOH F 6 . ? 18.482 43.197 27.208 1.00 36.92 ? 2761 HOH A O 1 HETATM 8974 O O . HOH F 6 . ? 62.082 81.169 -43.908 1.00 45.01 ? 2762 HOH A O 1 HETATM 8975 O O . HOH F 6 . ? 7.720 54.419 17.557 1.00 33.13 ? 2763 HOH A O 1 HETATM 8976 O O . HOH F 6 . ? 17.900 41.702 25.143 1.00 30.83 ? 2764 HOH A O 1 HETATM 8977 O O . HOH F 6 . ? 11.681 67.296 2.263 1.00 44.12 ? 2765 HOH A O 1 HETATM 8978 O O . HOH F 6 . ? 4.456 56.675 -6.490 1.00 25.43 ? 2766 HOH A O 1 HETATM 8979 O O . HOH F 6 . ? 22.238 76.767 8.595 1.00 26.35 ? 2767 HOH A O 1 HETATM 8980 O O . HOH F 6 . ? 25.804 87.704 -42.934 1.00 35.01 ? 2768 HOH A O 1 HETATM 8981 O O . HOH F 6 . ? 10.798 62.593 -11.959 1.00 35.16 ? 2769 HOH A O 1 HETATM 8982 O O . HOH F 6 . ? 37.155 39.757 26.349 1.00 45.94 ? 2770 HOH A O 1 HETATM 8983 O O . HOH F 6 . ? 23.168 88.809 -38.175 1.00 34.85 ? 2771 HOH A O 1 HETATM 8984 O O . HOH F 6 . ? 70.134 62.747 -24.277 1.00 41.57 ? 2772 HOH A O 1 HETATM 8985 O O . HOH F 6 . ? 22.702 64.403 18.391 1.00 25.25 ? 2773 HOH A O 1 HETATM 8986 O O . HOH F 6 . ? 67.056 38.439 -10.008 1.00 31.39 ? 2774 HOH A O 1 HETATM 8987 O O . HOH F 6 . ? 65.083 87.597 -41.526 1.00 44.28 ? 2775 HOH A O 1 HETATM 8988 O O . HOH F 6 . ? 20.875 65.478 -39.949 1.00 39.43 ? 2776 HOH A O 1 HETATM 8989 O O . HOH F 6 . ? 13.622 48.317 1.334 1.00 43.84 ? 2777 HOH A O 1 HETATM 8990 O O . HOH F 6 . ? 55.557 69.539 -38.309 1.00 37.97 ? 2778 HOH A O 1 HETATM 8991 O O . HOH F 6 . ? 69.700 81.919 -34.213 1.00 38.18 ? 2779 HOH A O 1 HETATM 8992 O O . HOH F 6 . ? 31.038 29.685 5.502 1.00 47.68 ? 2780 HOH A O 1 HETATM 8993 O O . HOH F 6 . ? 27.933 86.235 -14.718 1.00 18.64 ? 2781 HOH A O 1 HETATM 8994 O O . HOH F 6 . ? 66.304 50.422 0.397 1.00 44.77 ? 2782 HOH A O 1 HETATM 8995 O O . HOH F 6 . ? 28.169 63.781 13.998 1.00 20.19 ? 2783 HOH A O 1 HETATM 8996 O O . HOH F 6 . ? 52.382 72.481 18.401 1.00 24.54 ? 2784 HOH A O 1 HETATM 8997 O O . HOH F 6 . ? 46.844 75.106 -26.405 1.00 32.80 ? 2785 HOH A O 1 HETATM 8998 O O . HOH F 6 . ? 65.543 81.578 -4.439 1.00 35.24 ? 2786 HOH A O 1 HETATM 8999 O O . HOH F 6 . ? 48.365 72.372 -26.395 1.00 41.47 ? 2787 HOH A O 1 HETATM 9000 O O . HOH F 6 . ? 59.001 55.577 27.190 1.00 28.26 ? 2788 HOH A O 1 HETATM 9001 O O . HOH F 6 . ? 44.179 87.577 -16.203 1.00 45.36 ? 2789 HOH A O 1 HETATM 9002 O O . HOH F 6 . ? 63.822 76.931 -40.636 1.00 33.92 ? 2790 HOH A O 1 HETATM 9003 O O . HOH F 6 . ? 14.052 58.212 16.306 1.00 15.83 ? 2791 HOH A O 1 HETATM 9004 O O . HOH F 6 . ? 13.861 57.608 18.919 1.00 14.42 ? 2792 HOH A O 1 HETATM 9005 O O . HOH F 6 . ? 28.105 39.783 11.311 1.00 12.08 ? 2793 HOH A O 1 HETATM 9006 O O . HOH F 6 . ? 28.892 81.925 -35.824 1.00 18.91 ? 2794 HOH A O 1 HETATM 9007 O O . HOH F 6 . ? 12.449 55.930 -15.008 1.00 22.92 ? 2795 HOH A O 1 HETATM 9008 O O . HOH F 6 . ? 81.556 67.145 -13.626 1.00 23.18 ? 2796 HOH A O 1 HETATM 9009 O O . HOH F 6 . ? 58.876 58.015 0.735 1.00 28.14 ? 2797 HOH A O 1 HETATM 9010 O O . HOH F 6 . ? 49.251 68.313 6.637 1.00 22.82 ? 2798 HOH A O 1 HETATM 9011 O O . HOH F 6 . ? 68.418 79.271 -28.789 1.00 31.77 ? 2799 HOH A O 1 HETATM 9012 O O . HOH F 6 . ? 26.070 32.796 28.740 1.00 19.53 ? 2800 HOH A O 1 HETATM 9013 O O . HOH F 6 . ? 32.194 69.514 24.286 1.00 21.64 ? 2801 HOH A O 1 HETATM 9014 O O . HOH F 6 . ? 28.006 102.526 -19.126 1.00 22.54 ? 2802 HOH A O 1 HETATM 9015 O O . HOH F 6 . ? 71.659 73.809 -29.323 1.00 29.64 ? 2803 HOH A O 1 HETATM 9016 O O . HOH F 6 . ? 10.424 50.605 -8.991 1.00 25.83 ? 2804 HOH A O 1 HETATM 9017 O O . HOH F 6 . ? 37.412 83.550 -3.964 1.00 23.52 ? 2805 HOH A O 1 HETATM 9018 O O . HOH F 6 . ? 59.343 51.999 2.542 1.00 25.73 ? 2806 HOH A O 1 HETATM 9019 O O . HOH F 6 . ? 19.706 84.134 -18.291 1.00 29.47 ? 2807 HOH A O 1 HETATM 9020 O O . HOH F 6 . ? 44.014 79.234 -21.629 1.00 27.31 ? 2808 HOH A O 1 HETATM 9021 O O . HOH F 6 . ? 57.878 52.815 26.098 1.00 31.07 ? 2809 HOH A O 1 HETATM 9022 O O . HOH F 6 . ? 17.330 52.639 32.804 1.00 32.85 ? 2810 HOH A O 1 HETATM 9023 O O . HOH F 6 . ? 46.585 42.766 9.614 1.00 39.03 ? 2811 HOH A O 1 HETATM 9024 O O . HOH F 6 . ? 27.353 71.894 34.027 1.00 31.60 ? 2812 HOH A O 1 HETATM 9025 O O . HOH F 6 . ? 7.494 54.006 -10.136 1.00 29.71 ? 2813 HOH A O 1 HETATM 9026 O O . HOH F 6 . ? 50.020 46.749 -30.717 1.00 24.89 ? 2814 HOH A O 1 HETATM 9027 O O . HOH F 6 . ? 42.536 78.774 -29.527 1.00 40.04 ? 2815 HOH A O 1 HETATM 9028 O O . HOH F 6 . ? 27.826 89.032 -12.113 1.00 28.27 ? 2816 HOH A O 1 HETATM 9029 O O . HOH F 6 . ? 56.833 89.919 -43.820 1.00 41.11 ? 2817 HOH A O 1 HETATM 9030 O O . HOH F 6 . ? 20.692 64.958 -42.331 1.00 31.82 ? 2818 HOH A O 1 HETATM 9031 O O . HOH F 6 . ? 69.565 83.774 -36.181 1.00 38.51 ? 2819 HOH A O 1 HETATM 9032 O O . HOH F 6 . ? 57.868 92.977 -25.443 1.00 38.34 ? 2820 HOH A O 1 HETATM 9033 O O . HOH F 6 . ? 46.139 39.774 -0.074 1.00 31.27 ? 2821 HOH A O 1 HETATM 9034 O O . HOH F 6 . ? 37.021 37.527 24.872 1.00 37.41 ? 2822 HOH A O 1 HETATM 9035 O O . HOH F 6 . ? 52.113 68.581 4.419 1.00 34.66 ? 2823 HOH A O 1 HETATM 9036 O O . HOH F 6 . ? 15.464 76.973 -13.777 1.00 33.73 ? 2824 HOH A O 1 HETATM 9037 O O . HOH F 6 . ? 49.348 45.678 31.001 1.00 29.92 ? 2825 HOH A O 1 HETATM 9038 O O . HOH F 6 . ? 47.117 72.540 -17.737 1.00 36.43 ? 2826 HOH A O 1 HETATM 9039 O O . HOH F 6 . ? 70.594 78.107 -26.463 1.00 49.58 ? 2827 HOH A O 1 HETATM 9040 O O . HOH F 6 . ? 58.562 52.808 4.625 1.00 28.44 ? 2828 HOH A O 1 HETATM 9041 O O . HOH F 6 . ? 35.343 55.521 -34.791 1.00 28.33 ? 2829 HOH A O 1 HETATM 9042 O O . HOH F 6 . ? 41.362 82.652 -28.831 1.00 28.42 ? 2830 HOH A O 1 HETATM 9043 O O . HOH F 6 . ? 47.958 66.051 26.801 1.00 35.20 ? 2831 HOH A O 1 HETATM 9044 O O . HOH F 6 . ? 39.857 81.910 -22.156 1.00 34.88 ? 2832 HOH A O 1 HETATM 9045 O O . HOH F 6 . ? 22.178 65.590 32.490 1.00 31.48 ? 2833 HOH A O 1 HETATM 9046 O O . HOH F 6 . ? 58.770 48.976 18.868 1.00 33.21 ? 2834 HOH A O 1 HETATM 9047 O O . HOH F 6 . ? 30.948 81.349 7.481 1.00 46.62 ? 2835 HOH A O 1 HETATM 9048 O O . HOH F 6 . ? 50.298 45.144 -24.957 1.00 32.18 ? 2836 HOH A O 1 HETATM 9049 O O . HOH F 6 . ? 62.603 60.649 0.198 1.00 35.15 ? 2837 HOH A O 1 HETATM 9050 O O . HOH F 6 . ? 67.803 75.197 -35.167 1.00 40.72 ? 2838 HOH A O 1 HETATM 9051 O O . HOH F 6 . ? 22.697 39.219 -15.504 1.00 37.68 ? 2839 HOH A O 1 HETATM 9052 O O . HOH F 6 . ? 36.279 93.844 -29.730 1.00 35.41 ? 2840 HOH A O 1 HETATM 9053 O O . HOH F 6 . ? 74.034 79.945 -11.110 1.00 34.02 ? 2841 HOH A O 1 HETATM 9054 O O . HOH F 6 . ? 41.107 81.578 -3.958 1.00 46.41 ? 2842 HOH A O 1 HETATM 9055 O O . HOH F 6 . ? 13.171 62.808 11.793 1.00 35.82 ? 2843 HOH A O 1 HETATM 9056 O O . HOH F 6 . ? 56.586 75.920 0.166 1.00 39.76 ? 2844 HOH A O 1 HETATM 9057 O O . HOH F 6 . ? 74.235 51.934 1.316 1.00 36.71 ? 2845 HOH A O 1 HETATM 9058 O O . HOH F 6 . ? 21.759 61.448 -34.780 1.00 19.66 ? 2846 HOH A O 1 HETATM 9059 O O . HOH F 6 . ? 77.506 65.257 -15.024 1.00 35.16 ? 2847 HOH A O 1 HETATM 9060 O O . HOH F 6 . ? 16.791 41.878 32.068 1.00 46.86 ? 2848 HOH A O 1 HETATM 9061 O O . HOH F 6 . ? 10.221 63.051 -14.817 1.00 31.10 ? 2849 HOH A O 1 HETATM 9062 O O . HOH F 6 . ? 45.927 79.905 4.700 1.00 31.36 ? 2850 HOH A O 1 HETATM 9063 O O . HOH F 6 . ? 14.572 47.233 32.726 1.00 30.37 ? 2851 HOH A O 1 HETATM 9064 O O . HOH F 6 . ? 47.744 40.254 5.946 1.00 32.97 ? 2852 HOH A O 1 HETATM 9065 O O . HOH F 6 . ? 19.744 39.270 -3.742 1.00 39.98 ? 2853 HOH A O 1 HETATM 9066 O O . HOH F 6 . ? 25.982 58.955 -38.884 1.00 30.42 ? 2854 HOH A O 1 HETATM 9067 O O . HOH F 6 . ? 10.754 57.939 -21.044 1.00 44.38 ? 2855 HOH A O 1 HETATM 9068 O O . HOH F 6 . ? 78.031 72.187 -10.291 1.00 22.15 ? 2856 HOH A O 1 HETATM 9069 O O . HOH F 6 . ? 35.420 62.357 33.918 1.00 30.26 ? 2857 HOH A O 1 HETATM 9070 O O . HOH F 6 . ? 26.429 91.439 -31.949 1.00 40.21 ? 2858 HOH A O 1 HETATM 9071 O O . HOH F 6 . ? 49.191 41.818 8.044 1.00 31.03 ? 2859 HOH A O 1 HETATM 9072 O O . HOH F 6 . ? 44.787 92.509 -25.027 1.00 32.65 ? 2860 HOH A O 1 HETATM 9073 O O . HOH F 6 . ? 52.225 49.149 25.691 1.00 28.98 ? 2861 HOH A O 1 HETATM 9074 O O . HOH F 6 . ? 9.912 53.192 -12.158 1.00 31.93 ? 2862 HOH A O 1 HETATM 9075 O O . HOH F 6 . ? 59.169 50.867 14.793 1.00 34.09 ? 2863 HOH A O 1 HETATM 9076 O O . HOH F 6 . ? 51.984 50.636 27.230 1.00 33.12 ? 2864 HOH A O 1 HETATM 9077 O O . HOH F 6 . ? 7.532 58.242 -0.003 1.00 33.97 ? 2865 HOH A O 1 HETATM 9078 O O . HOH F 6 . ? 11.387 58.293 19.984 1.00 33.05 ? 2866 HOH A O 1 HETATM 9079 O O . HOH F 6 . ? 15.663 49.243 31.426 1.00 24.74 ? 2867 HOH A O 1 HETATM 9080 O O . HOH F 6 . ? 45.521 60.200 -31.684 1.00 33.65 ? 2868 HOH A O 1 HETATM 9081 O O . HOH F 6 . ? 5.439 57.057 6.473 1.00 29.22 ? 2869 HOH A O 1 HETATM 9082 O O . HOH F 6 . ? 47.177 81.559 -17.210 1.00 29.45 ? 2870 HOH A O 1 HETATM 9083 O O . HOH F 6 . ? 28.427 68.008 12.233 1.00 29.54 ? 2871 HOH A O 1 HETATM 9084 O O . HOH F 6 . ? 31.847 71.424 13.366 1.00 30.56 ? 2872 HOH A O 1 HETATM 9085 O O . HOH F 6 . ? 25.695 66.350 17.132 1.00 28.07 ? 2873 HOH A O 1 HETATM 9086 O O . HOH F 6 . ? 78.873 62.601 -22.973 1.00 30.04 ? 2874 HOH A O 1 HETATM 9087 O O . HOH F 6 . ? 29.492 65.980 10.575 1.00 16.73 ? 2875 HOH A O 1 HETATM 9088 O O . HOH F 6 . ? 28.500 63.513 11.126 1.00 21.44 ? 2876 HOH A O 1 HETATM 9089 O O . HOH F 6 . ? 27.840 66.496 14.508 1.00 35.81 ? 2877 HOH A O 1 HETATM 9090 O O . HOH F 6 . ? 36.473 56.548 -32.709 1.00 24.67 ? 2878 HOH A O 1 HETATM 9091 O O . HOH F 6 . ? 47.094 41.588 -14.779 1.00 20.01 ? 2879 HOH A O 1 HETATM 9092 O O . HOH F 6 . ? 24.762 33.068 6.537 1.00 23.93 ? 2880 HOH A O 1 HETATM 9093 O O . HOH F 6 . ? 25.698 36.475 -15.389 1.00 26.25 ? 2881 HOH A O 1 HETATM 9094 O O . HOH F 6 . ? 44.323 95.302 -30.552 1.00 35.57 ? 2882 HOH A O 1 HETATM 9095 O O . HOH F 6 . ? 56.595 66.983 4.970 1.00 25.48 ? 2883 HOH A O 1 HETATM 9096 O O . HOH F 6 . ? 29.890 59.220 35.151 1.00 30.81 ? 2884 HOH A O 1 HETATM 9097 O O . HOH F 6 . ? 47.400 78.394 11.641 1.00 30.46 ? 2885 HOH A O 1 HETATM 9098 O O . HOH F 6 . ? 19.696 63.005 35.040 1.00 33.08 ? 2886 HOH A O 1 HETATM 9099 O O . HOH F 6 . ? 9.985 58.071 -3.406 1.00 25.17 ? 2887 HOH A O 1 HETATM 9100 O O . HOH F 6 . ? 31.110 87.091 -3.184 1.00 34.17 ? 2888 HOH A O 1 HETATM 9101 O O . HOH F 6 . ? 18.167 59.540 31.546 1.00 26.74 ? 2889 HOH A O 1 HETATM 9102 O O . HOH F 6 . ? 41.854 40.933 27.364 1.00 36.25 ? 2890 HOH A O 1 HETATM 9103 O O . HOH F 6 . ? 57.632 48.482 25.351 1.00 28.21 ? 2891 HOH A O 1 HETATM 9104 O O . HOH F 6 . ? 15.756 73.502 5.339 1.00 28.91 ? 2892 HOH A O 1 HETATM 9105 O O . HOH F 6 . ? 31.742 96.603 -27.482 1.00 29.71 ? 2893 HOH A O 1 HETATM 9106 O O . HOH F 6 . ? 37.465 52.817 -32.287 1.00 34.66 ? 2894 HOH A O 1 HETATM 9107 O O . HOH F 6 . ? 49.540 41.188 1.133 1.00 33.90 ? 2895 HOH A O 1 HETATM 9108 O O . HOH F 6 . ? 35.262 85.226 -0.978 1.00 31.14 ? 2896 HOH A O 1 HETATM 9109 O O . HOH F 6 . ? 70.535 72.355 -34.424 1.00 35.83 ? 2897 HOH A O 1 HETATM 9110 O O . HOH F 6 . ? 13.931 88.395 -19.861 1.00 31.44 ? 2898 HOH A O 1 HETATM 9111 O O . HOH F 6 . ? 54.173 93.586 -24.919 1.00 31.24 ? 2899 HOH A O 1 HETATM 9112 O O . HOH F 6 . ? 22.009 68.251 -39.755 1.00 33.22 ? 2900 HOH A O 1 HETATM 9113 O O . HOH F 6 . ? 60.356 91.478 -31.446 1.00 30.86 ? 2901 HOH A O 1 HETATM 9114 O O . HOH F 6 . ? 52.103 69.158 9.132 1.00 33.94 ? 2902 HOH A O 1 HETATM 9115 O O . HOH F 6 . ? 11.371 62.159 5.539 1.00 31.80 ? 2903 HOH A O 1 HETATM 9116 O O . HOH F 6 . ? 21.323 63.725 14.643 1.00 35.09 ? 2904 HOH A O 1 HETATM 9117 O O . HOH F 6 . ? 40.888 83.587 -25.427 1.00 31.70 ? 2905 HOH A O 1 HETATM 9118 O O . HOH F 6 . ? 63.853 78.725 -38.027 1.00 32.34 ? 2906 HOH A O 1 HETATM 9119 O O . HOH F 6 . ? 22.277 34.584 12.692 1.00 39.14 ? 2907 HOH A O 1 HETATM 9120 O O . HOH F 6 . ? 30.577 43.466 40.338 1.00 40.05 ? 2908 HOH A O 1 HETATM 9121 O O . HOH F 6 . ? 10.996 66.139 -5.983 1.00 34.67 ? 2909 HOH A O 1 HETATM 9122 O O . HOH F 6 . ? 30.250 70.588 35.943 1.00 33.20 ? 2910 HOH A O 1 HETATM 9123 O O . HOH F 6 . ? 22.951 66.058 -43.193 1.00 34.73 ? 2911 HOH A O 1 HETATM 9124 O O . HOH F 6 . ? 63.373 59.631 16.997 1.00 27.91 ? 2912 HOH A O 1 HETATM 9125 O O . HOH F 6 . ? 49.724 58.252 -31.083 1.00 39.11 ? 2913 HOH A O 1 HETATM 9126 O O . HOH F 6 . ? 57.479 49.414 16.443 1.00 32.99 ? 2914 HOH A O 1 HETATM 9127 O O . HOH F 6 . ? 14.594 54.873 -26.339 1.00 30.99 ? 2915 HOH A O 1 HETATM 9128 O O . HOH F 6 . ? 47.425 99.740 -33.030 1.00 35.13 ? 2916 HOH A O 1 HETATM 9129 O O . HOH F 6 . ? 29.443 34.878 -16.262 1.00 40.88 ? 2917 HOH A O 1 HETATM 9130 O O . HOH F 6 . ? 60.848 61.406 13.548 1.00 39.32 ? 2918 HOH A O 1 HETATM 9131 O O . HOH F 6 . ? 26.703 99.160 -26.272 1.00 33.08 ? 2919 HOH A O 1 HETATM 9132 O O . HOH F 6 . ? 8.080 81.224 -4.501 1.00 38.53 ? 2920 HOH A O 1 HETATM 9133 O O . HOH F 6 . ? 35.452 63.382 -33.780 1.00 29.73 ? 2921 HOH A O 1 HETATM 9134 O O . HOH F 6 . ? 21.587 47.002 -34.616 1.00 38.85 ? 2922 HOH A O 1 HETATM 9135 O O . HOH F 6 . ? 14.893 73.673 -22.034 1.00 36.94 ? 2923 HOH A O 1 HETATM 9136 O O . HOH F 6 . ? 77.271 76.537 -12.240 1.00 34.44 ? 2924 HOH A O 1 HETATM 9137 O O . HOH F 6 . ? 45.124 43.516 17.744 1.00 30.48 ? 2925 HOH A O 1 HETATM 9138 O O . HOH F 6 . ? 62.767 82.698 -17.330 1.00 31.71 ? 2926 HOH A O 1 HETATM 9139 O O . HOH F 6 . ? 47.974 44.953 -30.948 1.00 34.25 ? 2927 HOH A O 1 HETATM 9140 O O . HOH F 6 . ? 33.386 32.421 -12.879 1.00 42.06 ? 2928 HOH A O 1 HETATM 9141 O O . HOH F 6 . ? 26.211 75.102 10.753 1.00 38.30 ? 2929 HOH A O 1 HETATM 9142 O O . HOH F 6 . ? 34.981 35.386 23.390 1.00 40.42 ? 2930 HOH A O 1 HETATM 9143 O O . HOH F 6 . ? 70.323 60.215 -23.040 1.00 38.82 ? 2931 HOH A O 1 HETATM 9144 O O . HOH F 6 . ? 68.099 88.403 -35.401 1.00 38.41 ? 2932 HOH A O 1 HETATM 9145 O O . HOH F 6 . ? 52.690 45.641 -27.372 1.00 40.90 ? 2933 HOH A O 1 HETATM 9146 O O . HOH F 6 . ? 24.358 63.681 11.563 1.00 41.08 ? 2934 HOH A O 1 HETATM 9147 O O . HOH F 6 . ? 14.564 39.747 12.827 1.00 32.53 ? 2935 HOH A O 1 HETATM 9148 O O . HOH F 6 . ? 33.375 57.168 -38.990 1.00 35.75 ? 2936 HOH A O 1 HETATM 9149 O O . HOH F 6 . ? 28.628 64.525 30.180 1.00 31.89 ? 2937 HOH A O 1 HETATM 9150 O O . HOH F 6 . ? 46.717 80.490 -22.471 1.00 27.85 ? 2938 HOH A O 1 HETATM 9151 O O . HOH F 6 . ? 36.339 36.212 -18.347 1.00 38.76 ? 2939 HOH A O 1 HETATM 9152 O O . HOH F 6 . ? 63.794 57.475 1.082 1.00 40.12 ? 2940 HOH A O 1 HETATM 9153 O O . HOH F 6 . ? 6.935 51.735 9.105 1.00 32.54 ? 2941 HOH A O 1 HETATM 9154 O O . HOH F 6 . ? 53.532 92.903 -40.458 1.00 38.06 ? 2942 HOH A O 1 HETATM 9155 O O . HOH F 6 . ? 64.472 49.824 -21.991 1.00 39.06 ? 2943 HOH A O 1 HETATM 9156 O O . HOH F 6 . ? 33.384 88.310 -18.942 1.00 50.62 ? 2944 HOH A O 1 HETATM 9157 O O . HOH F 6 . ? 35.341 73.644 15.101 1.00 33.06 ? 2945 HOH A O 1 HETATM 9158 O O . HOH F 6 . ? 62.591 83.140 -21.420 1.00 38.22 ? 2946 HOH A O 1 HETATM 9159 O O . HOH F 6 . ? 26.340 89.951 -21.989 1.00 41.05 ? 2947 HOH A O 1 HETATM 9160 O O . HOH F 6 . ? 53.999 45.202 -36.990 1.00 41.60 ? 2948 HOH A O 1 HETATM 9161 O O . HOH F 6 . ? 46.033 70.442 -39.780 1.00 30.97 ? 2949 HOH A O 1 HETATM 9162 O O . HOH F 6 . ? 12.722 70.908 24.867 1.00 39.40 ? 2950 HOH A O 1 HETATM 9163 O O . HOH F 6 . ? 56.058 53.366 29.902 1.00 36.50 ? 2951 HOH A O 1 HETATM 9164 O O . HOH F 6 . ? 46.612 43.087 -22.655 1.00 43.47 ? 2952 HOH A O 1 HETATM 9165 O O . HOH F 6 . ? 36.405 42.164 -26.914 1.00 46.76 ? 2953 HOH A O 1 HETATM 9166 O O . HOH F 6 . ? 21.695 35.271 34.451 1.00 40.97 ? 2954 HOH A O 1 HETATM 9167 O O . HOH F 6 . ? 19.768 81.858 -42.523 1.00 36.35 ? 2955 HOH A O 1 HETATM 9168 O O . HOH F 6 . ? 36.663 92.363 -17.866 1.00 34.09 ? 2956 HOH A O 1 HETATM 9169 O O . HOH F 6 . ? 35.572 86.006 -8.296 1.00 40.00 ? 2957 HOH A O 1 HETATM 9170 O O . HOH F 6 . ? 38.971 86.546 -41.576 1.00 27.34 ? 2958 HOH A O 1 HETATM 9171 O O . HOH F 6 . ? 22.676 48.922 -26.982 1.00 45.95 ? 2959 HOH A O 1 HETATM 9172 O O . HOH F 6 . ? 65.461 41.259 -21.093 1.00 43.04 ? 2960 HOH A O 1 HETATM 9173 O O . HOH F 6 . ? 60.343 51.476 5.989 1.00 32.17 ? 2961 HOH A O 1 HETATM 9174 O O . HOH F 6 . ? 35.000 36.240 3.150 1.00 37.73 ? 2962 HOH A O 1 HETATM 9175 O O . HOH F 6 . ? 65.046 77.068 -4.007 1.00 31.43 ? 2963 HOH A O 1 HETATM 9176 O O . HOH F 6 . ? 5.362 81.061 -3.510 1.00 33.02 ? 2964 HOH A O 1 HETATM 9177 O O . HOH F 6 . ? 40.637 35.901 8.334 1.00 45.55 ? 2965 HOH A O 1 HETATM 9178 O O . HOH F 6 . ? 24.575 87.116 -0.923 1.00 36.26 ? 2966 HOH A O 1 HETATM 9179 O O . HOH F 6 . ? 47.331 82.551 -20.189 1.00 40.84 ? 2967 HOH A O 1 HETATM 9180 O O . HOH F 6 . ? 75.554 48.215 -5.820 1.00 45.85 ? 2968 HOH A O 1 HETATM 9181 O O . HOH F 6 . ? 60.367 83.566 -16.789 1.00 46.01 ? 2969 HOH A O 1 HETATM 9182 O O . HOH F 6 . ? 74.707 77.501 -20.982 1.00 45.65 ? 2970 HOH A O 1 HETATM 9183 O O . HOH F 6 . ? 70.116 77.175 -31.718 1.00 35.28 ? 2971 HOH A O 1 HETATM 9184 O O . HOH F 6 . ? 47.318 58.105 -32.335 1.00 32.90 ? 2972 HOH A O 1 HETATM 9185 O O . HOH F 6 . ? 45.584 56.365 -32.776 1.00 35.82 ? 2973 HOH A O 1 HETATM 9186 O O . HOH F 6 . ? 36.551 66.761 25.528 1.00 27.39 ? 2974 HOH A O 1 HETATM 9187 O O . HOH F 6 . ? 9.727 53.499 21.871 1.00 39.30 ? 2975 HOH A O 1 HETATM 9188 O O . HOH F 6 . ? 43.161 69.459 -27.760 1.00 38.36 ? 2976 HOH A O 1 HETATM 9189 O O . HOH F 6 . ? 37.601 55.307 -36.521 1.00 37.13 ? 2977 HOH A O 1 HETATM 9190 O O . HOH F 6 . ? 16.231 30.890 18.064 1.00 37.17 ? 2978 HOH A O 1 HETATM 9191 O O . HOH F 6 . ? 22.648 59.916 38.421 1.00 42.50 ? 2979 HOH A O 1 HETATM 9192 O O . HOH F 6 . ? 21.543 48.726 -22.392 1.00 35.14 ? 2980 HOH A O 1 HETATM 9193 O O . HOH F 6 . ? 22.918 85.016 -17.039 1.00 37.10 ? 2981 HOH A O 1 HETATM 9194 O O . HOH F 6 . ? 30.025 89.789 -13.072 1.00 36.96 ? 2982 HOH A O 1 HETATM 9195 O O . HOH F 6 . ? 55.348 68.516 3.376 1.00 39.12 ? 2983 HOH A O 1 HETATM 9196 O O . HOH F 6 . ? 73.293 62.877 -0.764 1.00 37.80 ? 2984 HOH A O 1 HETATM 9197 O O . HOH F 6 . ? 76.754 49.911 -10.893 1.00 41.15 ? 2985 HOH A O 1 HETATM 9198 O O . HOH F 6 . ? 38.507 73.820 18.235 1.00 43.16 ? 2986 HOH A O 1 HETATM 9199 O O . HOH F 6 . ? 23.173 78.374 -42.256 1.00 38.89 ? 2987 HOH A O 1 HETATM 9200 O O . HOH F 6 . ? 10.498 62.015 -4.865 1.00 35.45 ? 2988 HOH A O 1 HETATM 9201 O O . HOH F 6 . ? 73.791 79.050 -13.479 1.00 42.17 ? 2989 HOH A O 1 HETATM 9202 O O . HOH F 6 . ? 49.978 80.998 -3.390 1.00 51.45 ? 2990 HOH A O 1 HETATM 9203 O O . HOH F 6 . ? 10.202 56.107 26.197 1.00 34.82 ? 2991 HOH A O 1 HETATM 9204 O O . HOH F 6 . ? 58.319 64.440 26.613 1.00 43.20 ? 2992 HOH A O 1 HETATM 9205 O O . HOH F 6 . ? 8.081 48.420 19.561 1.00 39.92 ? 2993 HOH A O 1 HETATM 9206 O O . HOH F 6 . ? 57.501 55.355 29.385 1.00 35.17 ? 2994 HOH A O 1 HETATM 9207 O O . HOH F 6 . ? 43.303 64.617 -31.607 1.00 36.91 ? 2995 HOH A O 1 HETATM 9208 O O . HOH F 6 . ? 50.935 90.459 -21.677 1.00 44.23 ? 2996 HOH A O 1 HETATM 9209 O O . HOH F 6 . ? 38.713 80.345 -3.204 1.00 39.13 ? 2997 HOH A O 1 HETATM 9210 O O . HOH F 6 . ? 74.607 62.805 -8.431 1.00 43.64 ? 2998 HOH A O 1 HETATM 9211 O O . HOH F 6 . ? 74.383 60.204 -9.818 1.00 35.61 ? 2999 HOH A O 1 HETATM 9212 O O . HOH F 6 . ? 61.608 55.476 27.370 1.00 38.21 ? 3000 HOH A O 1 HETATM 9213 O O . HOH F 6 . ? 14.125 68.626 5.200 1.00 38.32 ? 3001 HOH A O 1 HETATM 9214 O O . HOH F 6 . ? 51.887 60.454 28.100 1.00 35.51 ? 3002 HOH A O 1 HETATM 9215 O O . HOH F 6 . ? 18.183 36.764 5.583 1.00 34.86 ? 3003 HOH A O 1 HETATM 9216 O O . HOH F 6 . ? 64.952 87.881 -24.360 1.00 35.11 ? 3004 HOH A O 1 HETATM 9217 O O . HOH F 6 . ? 24.281 66.537 10.313 1.00 47.92 ? 3005 HOH A O 1 HETATM 9218 O O . HOH F 6 . ? 10.845 53.699 4.073 1.00 44.76 ? 3006 HOH A O 1 HETATM 9219 O O . HOH F 6 . ? 12.093 47.054 -12.038 1.00 43.02 ? 3007 HOH A O 1 HETATM 9220 O O . HOH F 6 . ? 27.020 47.535 -23.882 1.00 33.90 ? 3008 HOH A O 1 HETATM 9221 O O . HOH F 6 . ? 48.992 46.210 26.530 1.00 38.54 ? 3009 HOH A O 1 HETATM 9222 O O . HOH F 6 . ? 38.041 34.685 -6.666 1.00 46.58 ? 3010 HOH A O 1 HETATM 9223 O O . HOH F 6 . ? 32.416 31.036 16.122 1.00 37.46 ? 3011 HOH A O 1 HETATM 9224 O O . HOH F 6 . ? 39.536 38.404 -10.605 1.00 45.21 ? 3012 HOH A O 1 HETATM 9225 O O . HOH F 6 . ? 67.133 52.846 1.481 1.00 37.15 ? 3013 HOH A O 1 HETATM 9226 O O . HOH F 6 . ? 23.682 36.949 15.760 1.00 33.04 ? 3014 HOH A O 1 HETATM 9227 O O . HOH F 6 . ? 51.010 70.841 7.197 1.00 42.74 ? 3015 HOH A O 1 HETATM 9228 O O . HOH F 6 . ? 56.711 47.049 23.171 1.00 44.47 ? 3016 HOH A O 1 HETATM 9229 O O . HOH F 6 . ? 31.143 61.544 35.683 1.00 40.66 ? 3017 HOH A O 1 HETATM 9230 O O . HOH F 6 . ? 17.067 41.336 9.054 1.00 39.68 ? 3018 HOH A O 1 HETATM 9231 O O . HOH F 6 . ? 69.631 84.091 -17.873 1.00 47.05 ? 3019 HOH A O 1 HETATM 9232 O O . HOH F 6 . ? 10.241 41.836 11.951 1.00 36.37 ? 3020 HOH A O 1 HETATM 9233 O O . HOH F 6 . ? 13.073 62.398 -25.842 1.00 36.54 ? 3021 HOH A O 1 HETATM 9234 O O . HOH F 6 . ? 34.204 86.834 -44.039 1.00 35.69 ? 3022 HOH A O 1 HETATM 9235 O O . HOH F 6 . ? 31.672 57.007 -30.540 1.00 34.75 ? 3023 HOH A O 1 HETATM 9236 O O . HOH F 6 . ? 43.609 79.715 -27.718 1.00 39.13 ? 3024 HOH A O 1 HETATM 9237 O O . HOH F 6 . ? 37.796 34.999 -19.873 1.00 43.75 ? 3025 HOH A O 1 HETATM 9238 O O . HOH F 6 . ? 34.521 53.867 -33.433 1.00 45.79 ? 3026 HOH A O 1 HETATM 9239 O O . HOH F 6 . ? 43.580 92.733 -22.947 1.00 45.53 ? 3027 HOH A O 1 HETATM 9240 O O . HOH F 6 . ? 35.806 34.050 -21.916 1.00 44.64 ? 3028 HOH A O 1 HETATM 9241 O O . HOH F 6 . ? 44.794 45.665 32.288 1.00 45.66 ? 3029 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 SER 3 3 ? ? ? A . n A 1 4 HIS 4 4 ? ? ? A . n A 1 5 HIS 5 5 ? ? ? A . n A 1 6 HIS 6 6 ? ? ? A . n A 1 7 HIS 7 7 ? ? ? A . n A 1 8 HIS 8 8 ? ? ? A . n A 1 9 HIS 9 9 ? ? ? A . n A 1 10 GLY 10 10 ? ? ? A . n A 1 11 GLU 11 11 ? ? ? A . n A 1 12 PHE 12 12 ? ? ? A . n A 1 13 ASP 13 13 ? ? ? A . n A 1 14 ASP 14 14 ? ? ? A . n A 1 15 PRO 15 15 ? ? ? A . n A 1 16 ILE 16 16 ? ? ? A . n A 1 17 ARG 17 17 ? ? ? A . n A 1 18 PRO 18 18 ? ? ? A . n A 1 19 PRO 19 19 ? ? ? A . n A 1 20 LEU 20 20 ? ? ? A . n A 1 21 LYS 21 21 ? ? ? A . n A 1 22 VAL 22 22 ? ? ? A . n A 1 23 ALA 23 23 ? ? ? A . n A 1 24 ARG 24 24 ? ? ? A . n A 1 25 SER 25 25 ? ? ? A . n A 1 26 PRO 26 26 ? ? ? A . n A 1 27 ARG 27 27 ? ? ? A . n A 1 28 PRO 28 28 ? ? ? A . n A 1 29 GLY 29 29 ? ? ? A . n A 1 30 GLN 30 30 ? ? ? A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 GLN 32 32 32 GLN GLN A . n A 1 33 ASP 33 33 33 ASP ASP A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 VAL 35 35 35 VAL VAL A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 ASP 37 37 37 ASP ASP A . n A 1 38 VAL 38 38 38 VAL VAL A . n A 1 39 PRO 39 39 39 PRO PRO A . n A 1 40 ASN 40 40 40 ASN ASN A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 VAL 43 43 43 VAL VAL A . n A 1 44 GLN 44 44 44 GLN GLN A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 LEU 48 48 48 LEU LEU A . n A 1 49 TYR 49 49 49 TYR TYR A . n A 1 50 ASP 50 50 50 ASP ASP A . n A 1 51 ARG 51 51 51 ARG ARG A . n A 1 52 MET 52 52 52 MET MET A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 LYS 55 55 55 LYS LYS A . n A 1 56 ASP 56 56 56 ASP ASP A . n A 1 57 ILE 57 57 57 ILE ILE A . n A 1 58 ASP 58 58 58 ASP ASP A . n A 1 59 GLY 59 59 59 GLY GLY A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 VAL 61 61 61 VAL VAL A . n A 1 62 TRP 62 62 62 TRP TRP A . n A 1 63 LYS 63 63 63 LYS LYS A . n A 1 64 GLN 64 64 64 GLN GLN A . n A 1 65 GLY 65 65 65 GLY GLY A . n A 1 66 TRP 66 66 66 TRP TRP A . n A 1 67 ASN 67 67 67 ASN ASN A . n A 1 68 ILE 68 68 68 ILE ILE A . n A 1 69 LYS 69 69 69 LYS LYS A . n A 1 70 TYR 70 70 70 TYR TYR A . n A 1 71 ASP 71 71 71 ASP ASP A . n A 1 72 PRO 72 72 72 PRO PRO A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 LYS 74 74 74 LYS LYS A . n A 1 75 TYR 75 75 75 TYR TYR A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 HIS 78 78 78 HIS HIS A . n A 1 79 HIS 79 79 79 HIS HIS A . n A 1 80 LYS 80 80 80 LYS LYS A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 LYS 82 82 82 LYS LYS A . n A 1 83 VAL 83 83 83 VAL VAL A . n A 1 84 PHE 84 84 84 PHE PHE A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 PRO 87 87 87 PRO PRO A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 HIS 90 90 90 HIS HIS A . n A 1 91 ASN 91 91 91 ASN ASN A . n A 1 92 ASP 92 92 92 ASP ASP A . n A 1 93 PRO 93 93 93 PRO PRO A . n A 1 94 GLY 94 94 94 GLY GLY A . n A 1 95 TRP 95 95 95 TRP TRP A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 GLN 97 97 97 GLN GLN A . n A 1 98 THR 98 98 98 THR THR A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 GLU 100 100 100 GLU GLU A . n A 1 101 GLU 101 101 101 GLU GLU A . n A 1 102 TYR 102 102 102 TYR TYR A . n A 1 103 TYR 103 103 103 TYR TYR A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 HIS 105 105 105 HIS HIS A . n A 1 106 ASP 106 106 106 ASP ASP A . n A 1 107 THR 107 107 107 THR THR A . n A 1 108 LYS 108 108 108 LYS LYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 LEU 111 111 111 LEU LEU A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 ASN 113 113 113 ASN ASN A . n A 1 114 ALA 114 114 114 ALA ALA A . n A 1 115 LEU 115 115 115 LEU LEU A . n A 1 116 ARG 116 116 116 ARG ARG A . n A 1 117 HIS 117 117 117 HIS HIS A . n A 1 118 LEU 118 118 118 LEU LEU A . n A 1 119 HIS 119 119 119 HIS HIS A . n A 1 120 ASP 120 120 120 ASP ASP A . n A 1 121 ASN 121 121 121 ASN ASN A . n A 1 122 PRO 122 122 122 PRO PRO A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 MET 124 124 124 MET MET A . n A 1 125 LYS 125 125 125 LYS LYS A . n A 1 126 PHE 126 126 126 PHE PHE A . n A 1 127 ILE 127 127 127 ILE ILE A . n A 1 128 TRP 128 128 128 TRP TRP A . n A 1 129 ALA 129 129 129 ALA ALA A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 SER 132 132 132 SER SER A . n A 1 133 TYR 133 133 133 TYR TYR A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ALA 135 135 135 ALA ALA A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 HIS 139 139 139 HIS HIS A . n A 1 140 ASP 140 140 140 ASP ASP A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 GLY 142 142 142 GLY GLY A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 ASN 144 144 144 ASN ASN A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 LYS 146 146 146 LYS LYS A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 GLN 148 148 148 GLN GLN A . n A 1 149 MET 149 149 149 MET MET A . n A 1 150 LYS 150 150 150 LYS LYS A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 ILE 152 152 152 ILE ILE A . n A 1 153 VAL 153 153 153 VAL VAL A . n A 1 154 LYS 154 154 154 LYS LYS A . n A 1 155 ASN 155 155 155 ASN ASN A . n A 1 156 GLY 156 156 156 GLY GLY A . n A 1 157 GLN 157 157 157 GLN GLN A . n A 1 158 LEU 158 158 158 LEU LEU A . n A 1 159 GLU 159 159 159 GLU GLU A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 VAL 161 161 161 VAL VAL A . n A 1 162 THR 162 162 162 THR THR A . n A 1 163 GLY 163 163 163 GLY GLY A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 TRP 165 165 165 TRP TRP A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 MET 167 167 167 MET MET A . n A 1 168 PRO 168 168 168 PRO PRO A . n A 1 169 ASP 169 169 169 ASP ASP A . n A 1 170 GLU 170 170 170 GLU GLU A . n A 1 171 ALA 171 171 171 ALA ALA A . n A 1 172 ASN 172 172 172 ASN ASN A . n A 1 173 SER 173 173 173 SER SER A . n A 1 174 HIS 174 174 174 HIS HIS A . n A 1 175 TRP 175 175 175 TRP TRP A . n A 1 176 ARG 176 176 176 ARG ARG A . n A 1 177 ASN 177 177 177 ASN ASN A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLN 181 181 181 GLN GLN A . n A 1 182 LEU 182 182 182 LEU LEU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 GLY 185 185 185 GLY GLY A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 TRP 188 188 188 TRP TRP A . n A 1 189 LEU 189 189 189 LEU LEU A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 PHE 192 192 192 PHE PHE A . n A 1 193 MET 193 193 193 MET MET A . n A 1 194 ASN 194 194 194 ASN ASN A . n A 1 195 VAL 195 195 195 VAL VAL A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 THR 198 198 198 THR THR A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 SER 200 200 200 SER SER A . n A 1 201 TRP 201 201 201 TRP TRP A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 ILE 203 203 203 ILE ILE A . n A 1 204 ASP 204 204 204 ASP ASP A . n A 1 205 PRO 205 205 205 PRO PRO A . n A 1 206 PHE 206 206 206 PHE PHE A . n A 1 207 GLY 207 207 207 GLY GLY A . n A 1 208 HIS 208 208 208 HIS HIS A . n A 1 209 SER 209 209 209 SER SER A . n A 1 210 PRO 210 210 210 PRO PRO A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 MET 212 212 212 MET MET A . n A 1 213 PRO 213 213 213 PRO PRO A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 LYS 218 218 218 LYS LYS A . n A 1 219 SER 219 219 219 SER SER A . n A 1 220 GLY 220 220 220 GLY GLY A . n A 1 221 PHE 221 221 221 PHE PHE A . n A 1 222 LYS 222 222 222 LYS LYS A . n A 1 223 ASN 223 223 223 ASN ASN A . n A 1 224 MET 224 224 224 MET MET A . n A 1 225 LEU 225 225 225 LEU LEU A . n A 1 226 ILE 226 226 226 ILE ILE A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 ARG 228 228 228 ARG ARG A . n A 1 229 THR 229 229 229 THR THR A . n A 1 230 HIS 230 230 230 HIS HIS A . n A 1 231 TYR 231 231 231 TYR TYR A . n A 1 232 SER 232 232 232 SER SER A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 LYS 234 234 234 LYS LYS A . n A 1 235 LYS 235 235 235 LYS LYS A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 ALA 238 238 238 ALA ALA A . n A 1 239 GLN 239 239 239 GLN GLN A . n A 1 240 GLN 240 240 240 GLN GLN A . n A 1 241 ARG 241 241 241 ARG ARG A . n A 1 242 GLN 242 242 242 GLN GLN A . n A 1 243 LEU 243 243 243 LEU LEU A . n A 1 244 GLU 244 244 244 GLU GLU A . n A 1 245 PHE 245 245 245 PHE PHE A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 TRP 247 247 247 TRP TRP A . n A 1 248 ARG 248 248 248 ARG ARG A . n A 1 249 GLN 249 249 249 GLN GLN A . n A 1 250 ILE 250 250 250 ILE ILE A . n A 1 251 TRP 251 251 251 TRP TRP A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 GLY 255 255 255 GLY GLY A . n A 1 256 ASP 256 256 256 ASP ASP A . n A 1 257 THR 257 257 257 THR THR A . n A 1 258 ALA 258 258 258 ALA ALA A . n A 1 259 LEU 259 259 259 LEU LEU A . n A 1 260 PHE 260 260 260 PHE PHE A . n A 1 261 THR 261 261 261 THR THR A . n A 1 262 HIS 262 262 262 HIS HIS A . n A 1 263 MET 263 263 263 MET MET A . n A 1 264 MET 264 264 264 MET MET A . n A 1 265 PRO 265 265 265 PRO PRO A . n A 1 266 PHE 266 266 266 PHE PHE A . n A 1 267 TYR 267 267 267 TYR TYR A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 TYR 269 269 269 TYR TYR A . n A 1 270 ASP 270 270 270 ASP ASP A . n A 1 271 ILE 271 271 271 ILE ILE A . n A 1 272 PRO 272 272 272 PRO PRO A . n A 1 273 HIS 273 273 273 HIS HIS A . n A 1 274 THR 274 274 274 THR THR A . n A 1 275 CYS 275 275 275 CYS CYS A . n A 1 276 GLY 276 276 276 GLY GLY A . n A 1 277 PRO 277 277 277 PRO PRO A . n A 1 278 ASP 278 278 278 ASP ASP A . n A 1 279 PRO 279 279 279 PRO PRO A . n A 1 280 LYS 280 280 280 LYS LYS A . n A 1 281 VAL 281 281 281 VAL VAL A . n A 1 282 CYS 282 282 282 CYS CYS A . n A 1 283 CYS 283 283 283 CYS CYS A . n A 1 284 GLN 284 284 284 GLN GLN A . n A 1 285 PHE 285 285 285 PHE PHE A . n A 1 286 ASP 286 286 286 ASP ASP A . n A 1 287 PHE 287 287 287 PHE PHE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 ARG 289 289 289 ARG ARG A . n A 1 290 MET 290 290 290 MET MET A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 SER 292 292 292 SER SER A . n A 1 293 PHE 293 293 293 PHE PHE A . n A 1 294 GLY 294 294 294 GLY GLY A . n A 1 295 LEU 295 295 295 LEU LEU A . n A 1 296 SER 296 296 296 SER SER A . n A 1 297 CYS 297 297 297 CYS CYS A . n A 1 298 PRO 298 298 298 PRO PRO A . n A 1 299 TRP 299 299 299 TRP TRP A . n A 1 300 LYS 300 300 300 LYS LYS A . n A 1 301 VAL 301 301 301 VAL VAL A . n A 1 302 PRO 302 302 302 PRO PRO A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ARG 304 304 304 ARG ARG A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 ILE 306 306 306 ILE ILE A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 ASP 308 308 308 ASP ASP A . n A 1 309 GLN 309 309 309 GLN GLN A . n A 1 310 ASN 310 310 310 ASN ASN A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 ALA 313 313 313 ALA ALA A . n A 1 314 ARG 314 314 314 ARG ARG A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASP 316 316 316 ASP ASP A . n A 1 317 LEU 317 317 317 LEU LEU A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 GLN 321 321 321 GLN GLN A . n A 1 322 TRP 322 322 322 TRP TRP A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LYS 325 325 325 LYS LYS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 GLU 327 327 327 GLU GLU A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 TYR 329 329 329 TYR TYR A . n A 1 330 ARG 330 330 330 ARG ARG A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 ASN 332 332 332 ASN ASN A . n A 1 333 VAL 333 333 333 VAL VAL A . n A 1 334 LEU 334 334 334 LEU LEU A . n A 1 335 LEU 335 335 335 LEU LEU A . n A 1 336 ILE 336 336 336 ILE ILE A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 LEU 338 338 338 LEU LEU A . n A 1 339 GLY 339 339 339 GLY GLY A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASN 341 341 341 ASN ASN A . n A 1 342 PHE 342 342 342 PHE PHE A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLN 346 346 346 GLN GLN A . n A 1 347 ASN 347 347 347 ASN ASN A . n A 1 348 THR 348 348 348 THR THR A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 TRP 350 350 350 TRP TRP A . n A 1 351 ASP 351 351 351 ASP ASP A . n A 1 352 VAL 352 352 352 VAL VAL A . n A 1 353 GLN 353 353 353 GLN GLN A . n A 1 354 ARG 354 354 354 ARG ARG A . n A 1 355 VAL 355 355 355 VAL VAL A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 TYR 357 357 357 TYR TYR A . n A 1 358 GLU 358 358 358 GLU GLU A . n A 1 359 ARG 359 359 359 ARG ARG A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 PHE 361 361 361 PHE PHE A . n A 1 362 GLU 362 362 362 GLU GLU A . n A 1 363 HIS 363 363 363 HIS HIS A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 SER 366 366 366 SER SER A . n A 1 367 GLN 367 367 367 GLN GLN A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 HIS 369 369 369 HIS HIS A . n A 1 370 PHE 370 370 370 PHE PHE A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 VAL 372 372 372 VAL VAL A . n A 1 373 GLN 373 373 373 GLN GLN A . n A 1 374 ALA 374 374 374 ALA ALA A . n A 1 375 GLN 375 375 375 GLN GLN A . n A 1 376 PHE 376 376 376 PHE PHE A . n A 1 377 GLY 377 377 377 GLY GLY A . n A 1 378 THR 378 378 378 THR THR A . n A 1 379 LEU 379 379 379 LEU LEU A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 GLU 381 381 381 GLU GLU A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 PHE 383 383 383 PHE PHE A . n A 1 384 ASP 384 384 384 ASP ASP A . n A 1 385 ALA 385 385 385 ALA ALA A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 HIS 387 387 387 HIS HIS A . n A 1 388 GLN 388 388 388 GLN GLN A . n A 1 389 ALA 389 389 389 ALA ALA A . n A 1 390 GLU 390 390 390 GLU GLU A . n A 1 391 ARG 391 391 391 ARG ARG A . n A 1 392 ALA 392 392 392 ALA ALA A . n A 1 393 GLY 393 393 393 GLY GLY A . n A 1 394 GLN 394 394 394 GLN GLN A . n A 1 395 ALA 395 395 395 ALA ALA A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PHE 397 397 397 PHE PHE A . n A 1 398 PRO 398 398 398 PRO PRO A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 SER 401 401 401 SER SER A . n A 1 402 GLY 402 402 402 GLY GLY A . n A 1 403 ASP 403 403 403 ASP ASP A . n A 1 404 PHE 404 404 404 PHE PHE A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 TYR 407 407 407 TYR TYR A . n A 1 408 ALA 408 408 408 ALA ALA A . n A 1 409 ASP 409 409 409 ASP ASP A . n A 1 410 ARG 410 410 410 ARG ARG A . n A 1 411 SER 411 411 411 SER SER A . n A 1 412 ASP 412 412 412 ASP ASP A . n A 1 413 ASN 413 413 413 ASN ASN A . n A 1 414 TYR 414 414 414 TYR TYR A . n A 1 415 TRP 415 415 415 TRP TRP A . n A 1 416 SER 416 416 416 SER SER A . n A 1 417 GLY 417 417 417 GLY GLY A . n A 1 418 TYR 418 418 418 TYR TYR A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 THR 420 420 420 THR THR A . n A 1 421 SER 421 421 421 SER SER A . n A 1 422 ARG 422 422 422 ARG ARG A . n A 1 423 PRO 423 423 423 PRO PRO A . n A 1 424 TYR 424 424 424 TYR TYR A . n A 1 425 HIS 425 425 425 HIS HIS A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 ARG 427 427 427 ARG ARG A . n A 1 428 MET 428 428 428 MET MET A . n A 1 429 ASP 429 429 429 ASP ASP A . n A 1 430 ARG 430 430 430 ARG ARG A . n A 1 431 VAL 431 431 431 VAL VAL A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 MET 433 433 433 MET MET A . n A 1 434 HIS 434 434 434 HIS HIS A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 ARG 437 437 437 ARG ARG A . n A 1 438 ALA 438 438 438 ALA ALA A . n A 1 439 ALA 439 439 439 ALA ALA A . n A 1 440 GLU 440 440 440 GLU GLU A . n A 1 441 MET 441 441 441 MET MET A . n A 1 442 LEU 442 442 442 LEU LEU A . n A 1 443 SER 443 443 443 SER SER A . n A 1 444 ALA 444 444 444 ALA ALA A . n A 1 445 TRP 445 445 445 TRP TRP A . n A 1 446 HIS 446 446 446 HIS HIS A . n A 1 447 SER 447 447 447 SER SER A . n A 1 448 TRP 448 448 448 TRP TRP A . n A 1 449 ASP 449 449 449 ASP ASP A . n A 1 450 GLY 450 450 450 GLY GLY A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ALA 452 452 452 ALA ALA A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 GLU 455 455 455 GLU GLU A . n A 1 456 GLU 456 456 456 GLU GLU A . n A 1 457 ARG 457 457 457 ARG ARG A . n A 1 458 LEU 458 458 458 LEU LEU A . n A 1 459 GLU 459 459 459 GLU GLU A . n A 1 460 GLN 460 460 460 GLN GLN A . n A 1 461 ALA 461 461 461 ALA ALA A . n A 1 462 ARG 462 462 462 ARG ARG A . n A 1 463 ARG 463 463 463 ARG ARG A . n A 1 464 GLU 464 464 464 GLU GLU A . n A 1 465 LEU 465 465 465 LEU LEU A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 GLN 469 469 469 GLN GLN A . n A 1 470 HIS 470 470 470 HIS HIS A . n A 1 471 HIS 471 471 471 HIS HIS A . n A 1 472 ASP 472 472 472 ASP ASP A . n A 1 473 GLY 473 473 473 GLY GLY A . n A 1 474 ILE 474 474 474 ILE ILE A . n A 1 475 THR 475 475 475 THR THR A . n A 1 476 GLY 476 476 476 GLY GLY A . n A 1 477 THR 477 477 477 THR THR A . n A 1 478 ALA 478 478 478 ALA ALA A . n A 1 479 LYS 479 479 479 LYS LYS A . n A 1 480 THR 480 480 480 THR THR A . n A 1 481 HIS 481 481 481 HIS HIS A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 VAL 483 483 483 VAL VAL A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 TYR 486 486 486 TYR TYR A . n A 1 487 GLU 487 487 487 GLU GLU A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 ARG 489 489 489 ARG ARG A . n A 1 490 MET 490 490 490 MET MET A . n A 1 491 GLN 491 491 491 GLN GLN A . n A 1 492 GLU 492 492 492 GLU GLU A . n A 1 493 ALA 493 493 493 ALA ALA A . n A 1 494 LEU 494 494 494 LEU LEU A . n A 1 495 LYS 495 495 495 LYS LYS A . n A 1 496 ALA 496 496 496 ALA ALA A . n A 1 497 CYS 497 497 497 CYS CYS A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 MET 499 499 499 MET MET A . n A 1 500 VAL 500 500 500 VAL VAL A . n A 1 501 MET 501 501 501 MET MET A . n A 1 502 GLN 502 502 502 GLN GLN A . n A 1 503 GLN 503 503 503 GLN GLN A . n A 1 504 SER 504 504 504 SER SER A . n A 1 505 VAL 505 505 505 VAL VAL A . n A 1 506 TYR 506 506 506 TYR TYR A . n A 1 507 ARG 507 507 507 ARG ARG A . n A 1 508 LEU 508 508 508 LEU LEU A . n A 1 509 LEU 509 509 509 LEU LEU A . n A 1 510 THR 510 510 510 THR THR A . n A 1 511 LYS 511 511 511 LYS LYS A . n A 1 512 PRO 512 512 512 PRO PRO A . n A 1 513 SER 513 513 513 SER SER A . n A 1 514 ILE 514 514 514 ILE ILE A . n A 1 515 TYR 515 515 515 TYR TYR A . n A 1 516 SER 516 516 516 SER SER A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASP 518 518 518 ASP ASP A . n A 1 519 PHE 519 519 519 PHE PHE A . n A 1 520 SER 520 520 520 SER SER A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 SER 522 522 522 SER SER A . n A 1 523 TYR 523 523 523 TYR TYR A . n A 1 524 PHE 524 524 524 PHE PHE A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 LEU 526 526 526 LEU LEU A . n A 1 527 ASP 527 527 527 ASP ASP A . n A 1 528 ASP 528 528 528 ASP ASP A . n A 1 529 SER 529 529 529 SER SER A . n A 1 530 ARG 530 530 530 ARG ARG A . n A 1 531 TRP 531 531 531 TRP TRP A . n A 1 532 PRO 532 532 532 PRO PRO A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 SER 534 534 534 SER SER A . n A 1 535 GLY 535 535 535 GLY GLY A . n A 1 536 VAL 536 536 536 VAL VAL A . n A 1 537 GLU 537 537 537 GLU GLU A . n A 1 538 ASP 538 538 538 ASP ASP A . n A 1 539 SER 539 539 539 SER SER A . n A 1 540 ARG 540 540 540 ARG ARG A . n A 1 541 THR 541 541 541 THR THR A . n A 1 542 THR 542 542 542 THR THR A . n A 1 543 ILE 543 543 543 ILE ILE A . n A 1 544 ILE 544 544 544 ILE ILE A . n A 1 545 LEU 545 545 545 LEU LEU A . n A 1 546 GLY 546 546 546 GLY GLY A . n A 1 547 GLU 547 547 547 GLU GLU A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ILE 549 549 549 ILE ILE A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 PRO 551 551 551 PRO PRO A . n A 1 552 SER 552 552 552 SER SER A . n A 1 553 LYS 553 553 553 LYS LYS A . n A 1 554 HIS 554 554 554 HIS HIS A . n A 1 555 VAL 555 555 555 VAL VAL A . n A 1 556 VAL 556 556 556 VAL VAL A . n A 1 557 MET 557 557 557 MET MET A . n A 1 558 HIS 558 558 558 HIS HIS A . n A 1 559 ASN 559 559 559 ASN ASN A . n A 1 560 THR 560 560 560 THR THR A . n A 1 561 LEU 561 561 561 LEU LEU A . n A 1 562 PRO 562 562 562 PRO PRO A . n A 1 563 HIS 563 563 563 HIS HIS A . n A 1 564 TRP 564 564 564 TRP TRP A . n A 1 565 ARG 565 565 565 ARG ARG A . n A 1 566 GLU 566 566 566 GLU GLU A . n A 1 567 GLN 567 567 567 GLN GLN A . n A 1 568 LEU 568 568 568 LEU LEU A . n A 1 569 VAL 569 569 569 VAL VAL A . n A 1 570 ASP 570 570 570 ASP ASP A . n A 1 571 PHE 571 571 571 PHE PHE A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 VAL 573 573 573 VAL VAL A . n A 1 574 SER 574 574 574 SER SER A . n A 1 575 SER 575 575 575 SER SER A . n A 1 576 PRO 576 576 576 PRO PRO A . n A 1 577 PHE 577 577 577 PHE PHE A . n A 1 578 VAL 578 578 578 VAL VAL A . n A 1 579 SER 579 579 579 SER SER A . n A 1 580 VAL 580 580 580 VAL VAL A . n A 1 581 THR 581 581 581 THR THR A . n A 1 582 ASP 582 582 582 ASP ASP A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 ALA 584 584 584 ALA ALA A . n A 1 585 ASN 585 585 585 ASN ASN A . n A 1 586 ASN 586 586 586 ASN ASN A . n A 1 587 PRO 587 587 587 PRO PRO A . n A 1 588 VAL 588 588 588 VAL VAL A . n A 1 589 GLU 589 589 589 GLU GLU A . n A 1 590 ALA 590 590 590 ALA ALA A . n A 1 591 GLN 591 591 591 GLN GLN A . n A 1 592 VAL 592 592 592 VAL VAL A . n A 1 593 SER 593 593 593 SER SER A . n A 1 594 PRO 594 594 594 PRO PRO A . n A 1 595 VAL 595 595 595 VAL VAL A . n A 1 596 TRP 596 596 596 TRP TRP A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 TRP 598 598 598 TRP TRP A . n A 1 599 HIS 599 599 599 HIS HIS A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASP 601 601 601 ASP ASP A . n A 1 602 THR 602 602 602 THR THR A . n A 1 603 LEU 603 603 603 LEU LEU A . n A 1 604 THR 604 604 604 THR THR A . n A 1 605 LYS 605 605 605 LYS LYS A . n A 1 606 THR 606 606 606 THR THR A . n A 1 607 ILE 607 607 607 ILE ILE A . n A 1 608 HIS 608 608 608 HIS HIS A . n A 1 609 PRO 609 609 609 PRO PRO A . n A 1 610 GLN 610 610 610 GLN GLN A . n A 1 611 GLY 611 611 611 GLY GLY A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 THR 613 613 613 THR THR A . n A 1 614 THR 614 614 614 THR THR A . n A 1 615 LYS 615 615 615 LYS LYS A . n A 1 616 TYR 616 616 616 TYR TYR A . n A 1 617 ARG 617 617 617 ARG ARG A . n A 1 618 ILE 618 618 618 ILE ILE A . n A 1 619 ILE 619 619 619 ILE ILE A . n A 1 620 PHE 620 620 620 PHE PHE A . n A 1 621 LYS 621 621 621 LYS LYS A . n A 1 622 ALA 622 622 622 ALA ALA A . n A 1 623 ARG 623 623 623 ARG ARG A . n A 1 624 VAL 624 624 624 VAL VAL A . n A 1 625 PRO 625 625 625 PRO PRO A . n A 1 626 PRO 626 626 626 PRO PRO A . n A 1 627 MET 627 627 627 MET MET A . n A 1 628 GLY 628 628 628 GLY GLY A . n A 1 629 LEU 629 629 629 LEU LEU A . n A 1 630 ALA 630 630 630 ALA ALA A . n A 1 631 THR 631 631 631 THR THR A . n A 1 632 TYR 632 632 632 TYR TYR A . n A 1 633 VAL 633 633 633 VAL VAL A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 THR 635 635 635 THR THR A . n A 1 636 ILE 636 636 636 ILE ILE A . n A 1 637 SER 637 637 637 SER SER A . n A 1 638 ASP 638 638 638 ASP ASP A . n A 1 639 SER 639 639 639 SER SER A . n A 1 640 LYS 640 640 640 LYS LYS A . n A 1 641 PRO 641 641 641 PRO PRO A . n A 1 642 GLU 642 642 642 GLU GLU A . n A 1 643 HIS 643 643 643 HIS HIS A . n A 1 644 THR 644 644 644 THR THR A . n A 1 645 SER 645 645 645 SER SER A . n A 1 646 TYR 646 646 646 TYR TYR A . n A 1 647 ALA 647 647 647 ALA ALA A . n A 1 648 SER 648 648 648 SER SER A . n A 1 649 ASN 649 649 649 ASN ASN A . n A 1 650 LEU 650 650 650 LEU LEU A . n A 1 651 LEU 651 651 651 LEU LEU A . n A 1 652 LEU 652 652 652 LEU LEU A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 LYS 654 654 654 LYS LYS A . n A 1 655 ASN 655 655 655 ASN ASN A . n A 1 656 PRO 656 656 656 PRO PRO A . n A 1 657 THR 657 657 657 THR THR A . n A 1 658 SER 658 658 658 SER SER A . n A 1 659 LEU 659 659 659 LEU LEU A . n A 1 660 PRO 660 660 660 PRO PRO A . n A 1 661 LEU 661 661 661 LEU LEU A . n A 1 662 GLY 662 662 662 GLY GLY A . n A 1 663 GLN 663 663 663 GLN GLN A . n A 1 664 TYR 664 664 664 TYR TYR A . n A 1 665 PRO 665 665 665 PRO PRO A . n A 1 666 GLU 666 666 666 GLU GLU A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 LYS 669 669 669 LYS LYS A . n A 1 670 PHE 670 670 670 PHE PHE A . n A 1 671 GLY 671 671 671 GLY GLY A . n A 1 672 ASP 672 672 672 ASP ASP A . n A 1 673 PRO 673 673 673 PRO PRO A . n A 1 674 ARG 674 674 674 ARG ARG A . n A 1 675 GLU 675 675 675 GLU GLU A . n A 1 676 ILE 676 676 676 ILE ILE A . n A 1 677 SER 677 677 677 SER SER A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 ARG 679 679 679 ARG ARG A . n A 1 680 VAL 680 680 680 VAL VAL A . n A 1 681 GLY 681 681 681 GLY GLY A . n A 1 682 ASN 682 682 682 ASN ASN A . n A 1 683 GLY 683 683 683 GLY GLY A . n A 1 684 PRO 684 684 684 PRO PRO A . n A 1 685 THR 685 685 685 THR THR A . n A 1 686 LEU 686 686 686 LEU LEU A . n A 1 687 ALA 687 687 687 ALA ALA A . n A 1 688 PHE 688 688 688 PHE PHE A . n A 1 689 SER 689 689 689 SER SER A . n A 1 690 GLU 690 690 690 GLU GLU A . n A 1 691 GLN 691 691 691 GLN GLN A . n A 1 692 GLY 692 692 692 GLY GLY A . n A 1 693 LEU 693 693 693 LEU LEU A . n A 1 694 LEU 694 694 694 LEU LEU A . n A 1 695 LYS 695 695 695 LYS LYS A . n A 1 696 SER 696 696 696 SER SER A . n A 1 697 ILE 697 697 697 ILE ILE A . n A 1 698 GLN 698 698 698 GLN GLN A . n A 1 699 LEU 699 699 699 LEU LEU A . n A 1 700 THR 700 700 700 THR THR A . n A 1 701 GLN 701 701 701 GLN GLN A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 SER 703 703 703 SER SER A . n A 1 704 PRO 704 704 704 PRO PRO A . n A 1 705 HIS 705 705 705 HIS HIS A . n A 1 706 VAL 706 706 706 VAL VAL A . n A 1 707 PRO 707 707 707 PRO PRO A . n A 1 708 VAL 708 708 708 VAL VAL A . n A 1 709 HIS 709 709 709 HIS HIS A . n A 1 710 PHE 710 710 710 PHE PHE A . n A 1 711 LYS 711 711 711 LYS LYS A . n A 1 712 PHE 712 712 712 PHE PHE A . n A 1 713 LEU 713 713 713 LEU LEU A . n A 1 714 LYS 714 714 714 LYS LYS A . n A 1 715 TYR 715 715 715 TYR TYR A . n A 1 716 GLY 716 716 716 GLY GLY A . n A 1 717 VAL 717 717 717 VAL VAL A . n A 1 718 ARG 718 718 718 ARG ARG A . n A 1 719 SER 719 719 719 SER SER A . n A 1 720 HIS 720 720 720 HIS HIS A . n A 1 721 GLY 721 721 721 GLY GLY A . n A 1 722 ASP 722 722 722 ASP ASP A . n A 1 723 ARG 723 723 723 ARG ARG A . n A 1 724 SER 724 724 724 SER SER A . n A 1 725 GLY 725 725 725 GLY GLY A . n A 1 726 ALA 726 726 726 ALA ALA A . n A 1 727 TYR 727 727 727 TYR TYR A . n A 1 728 LEU 728 728 728 LEU LEU A . n A 1 729 PHE 729 729 729 PHE PHE A . n A 1 730 LEU 730 730 730 LEU LEU A . n A 1 731 PRO 731 731 731 PRO PRO A . n A 1 732 ASN 732 732 732 ASN ASN A . n A 1 733 GLY 733 733 733 GLY GLY A . n A 1 734 PRO 734 734 734 PRO PRO A . n A 1 735 ALA 735 735 735 ALA ALA A . n A 1 736 SER 736 736 736 SER SER A . n A 1 737 PRO 737 737 737 PRO PRO A . n A 1 738 VAL 738 738 738 VAL VAL A . n A 1 739 GLU 739 739 739 GLU GLU A . n A 1 740 LEU 740 740 740 LEU LEU A . n A 1 741 GLY 741 741 741 GLY GLY A . n A 1 742 GLN 742 742 742 GLN GLN A . n A 1 743 PRO 743 743 743 PRO PRO A . n A 1 744 VAL 744 744 744 VAL VAL A . n A 1 745 VAL 745 745 745 VAL VAL A . n A 1 746 LEU 746 746 746 LEU LEU A . n A 1 747 VAL 747 747 747 VAL VAL A . n A 1 748 THR 748 748 748 THR THR A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 GLY 750 750 750 GLY GLY A . n A 1 751 LYS 751 751 751 LYS LYS A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLU 753 753 753 GLU GLU A . n A 1 754 SER 754 754 754 SER SER A . n A 1 755 SER 755 755 755 SER SER A . n A 1 756 VAL 756 756 756 VAL VAL A . n A 1 757 SER 757 757 757 SER SER A . n A 1 758 VAL 758 758 758 VAL VAL A . n A 1 759 GLY 759 759 759 GLY GLY A . n A 1 760 LEU 760 760 760 LEU LEU A . n A 1 761 PRO 761 761 761 PRO PRO A . n A 1 762 SER 762 762 762 SER SER A . n A 1 763 VAL 763 763 763 VAL VAL A . n A 1 764 VAL 764 764 764 VAL VAL A . n A 1 765 HIS 765 765 765 HIS HIS A . n A 1 766 GLN 766 766 766 GLN GLN A . n A 1 767 THR 767 767 767 THR THR A . n A 1 768 ILE 768 768 768 ILE ILE A . n A 1 769 MET 769 769 769 MET MET A . n A 1 770 ARG 770 770 770 ARG ARG A . n A 1 771 GLY 771 771 771 GLY GLY A . n A 1 772 GLY 772 772 772 GLY GLY A . n A 1 773 ALA 773 773 773 ALA ALA A . n A 1 774 PRO 774 774 774 PRO PRO A . n A 1 775 GLU 775 775 775 GLU GLU A . n A 1 776 ILE 776 776 776 ILE ILE A . n A 1 777 ARG 777 777 777 ARG ARG A . n A 1 778 ASN 778 778 778 ASN ASN A . n A 1 779 LEU 779 779 779 LEU LEU A . n A 1 780 VAL 780 780 780 VAL VAL A . n A 1 781 ASP 781 781 781 ASP ASP A . n A 1 782 ILE 782 782 782 ILE ILE A . n A 1 783 GLY 783 783 783 GLY GLY A . n A 1 784 SER 784 784 784 SER SER A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 ASP 786 786 786 ASP ASP A . n A 1 787 ASN 787 787 787 ASN ASN A . n A 1 788 THR 788 788 788 THR THR A . n A 1 789 GLU 789 789 789 GLU GLU A . n A 1 790 ILE 790 790 790 ILE ILE A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 MET 792 792 792 MET MET A . n A 1 793 ARG 793 793 793 ARG ARG A . n A 1 794 LEU 794 794 794 LEU LEU A . n A 1 795 GLU 795 795 795 GLU GLU A . n A 1 796 THR 796 796 796 THR THR A . n A 1 797 HIS 797 797 797 HIS HIS A . n A 1 798 ILE 798 798 798 ILE ILE A . n A 1 799 ASP 799 799 799 ASP ASP A . n A 1 800 SER 800 800 800 SER SER A . n A 1 801 GLY 801 801 801 GLY GLY A . n A 1 802 ASP 802 802 802 ASP ASP A . n A 1 803 ILE 803 803 803 ILE ILE A . n A 1 804 PHE 804 804 804 PHE PHE A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 THR 806 806 806 THR THR A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 LEU 808 808 808 LEU LEU A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 GLY 810 810 810 GLY GLY A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 GLN 812 812 812 GLN GLN A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ILE 814 814 814 ILE ILE A . n A 1 815 LYS 815 815 815 LYS LYS A . n A 1 816 ARG 816 816 816 ARG ARG A . n A 1 817 ARG 817 817 817 ARG ARG A . n A 1 818 ARG 818 818 818 ARG ARG A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 ASP 820 820 820 ASP ASP A . n A 1 821 LYS 821 821 821 LYS LYS A . n A 1 822 LEU 822 822 822 LEU LEU A . n A 1 823 PRO 823 823 823 PRO PRO A . n A 1 824 LEU 824 824 824 LEU LEU A . n A 1 825 GLN 825 825 825 GLN GLN A . n A 1 826 ALA 826 826 826 ALA ALA A . n A 1 827 ASN 827 827 827 ASN ASN A . n A 1 828 TYR 828 828 828 TYR TYR A . n A 1 829 TYR 829 829 829 TYR TYR A . n A 1 830 PRO 830 830 830 PRO PRO A . n A 1 831 ILE 831 831 831 ILE ILE A . n A 1 832 PRO 832 832 832 PRO PRO A . n A 1 833 SER 833 833 833 SER SER A . n A 1 834 GLY 834 834 834 GLY GLY A . n A 1 835 MET 835 835 835 MET MET A . n A 1 836 PHE 836 836 836 PHE PHE A . n A 1 837 ILE 837 837 837 ILE ILE A . n A 1 838 GLU 838 838 838 GLU GLU A . n A 1 839 ASP 839 839 839 ASP ASP A . n A 1 840 ALA 840 840 840 ALA ALA A . n A 1 841 ASN 841 841 841 ASN ASN A . n A 1 842 THR 842 842 842 THR THR A . n A 1 843 ARG 843 843 843 ARG ARG A . n A 1 844 LEU 844 844 844 LEU LEU A . n A 1 845 THR 845 845 845 THR THR A . n A 1 846 LEU 846 846 846 LEU LEU A . n A 1 847 LEU 847 847 847 LEU LEU A . n A 1 848 THR 848 848 848 THR THR A . n A 1 849 GLY 849 849 849 GLY GLY A . n A 1 850 GLN 850 850 850 GLN GLN A . n A 1 851 PRO 851 851 851 PRO PRO A . n A 1 852 LEU 852 852 852 LEU LEU A . n A 1 853 GLY 853 853 853 GLY GLY A . n A 1 854 GLY 854 854 854 GLY GLY A . n A 1 855 SER 855 855 855 SER SER A . n A 1 856 SER 856 856 856 SER SER A . n A 1 857 LEU 857 857 857 LEU LEU A . n A 1 858 ALA 858 858 858 ALA ALA A . n A 1 859 SER 859 859 859 SER SER A . n A 1 860 GLY 860 860 860 GLY GLY A . n A 1 861 GLU 861 861 861 GLU GLU A . n A 1 862 LEU 862 862 862 LEU LEU A . n A 1 863 GLU 863 863 863 GLU GLU A . n A 1 864 ILE 864 864 864 ILE ILE A . n A 1 865 MET 865 865 865 MET MET A . n A 1 866 GLN 866 866 866 GLN GLN A . n A 1 867 ASP 867 867 867 ASP ASP A . n A 1 868 ARG 868 868 868 ARG ARG A . n A 1 869 ARG 869 869 869 ARG ARG A . n A 1 870 LEU 870 870 870 LEU LEU A . n A 1 871 ALA 871 871 871 ALA ALA A . n A 1 872 SER 872 872 872 SER SER A . n A 1 873 ASP 873 873 873 ASP ASP A . n A 1 874 ASP 874 874 874 ASP ASP A . n A 1 875 GLU 875 875 875 GLU GLU A . n A 1 876 ARG 876 876 876 ARG ARG A . n A 1 877 GLY 877 877 877 GLY GLY A . n A 1 878 LEU 878 878 878 LEU LEU A . n A 1 879 GLY 879 879 879 GLY GLY A . n A 1 880 GLN 880 880 880 GLN GLN A . n A 1 881 GLY 881 881 881 GLY GLY A . n A 1 882 VAL 882 882 882 VAL VAL A . n A 1 883 LEU 883 883 883 LEU LEU A . n A 1 884 ASP 884 884 884 ASP ASP A . n A 1 885 ASN 885 885 885 ASN ASN A . n A 1 886 LYS 886 886 886 LYS LYS A . n A 1 887 PRO 887 887 887 PRO PRO A . n A 1 888 VAL 888 888 888 VAL VAL A . n A 1 889 LEU 889 889 889 LEU LEU A . n A 1 890 HIS 890 890 890 HIS HIS A . n A 1 891 ILE 891 891 891 ILE ILE A . n A 1 892 TYR 892 892 892 TYR TYR A . n A 1 893 ARG 893 893 893 ARG ARG A . n A 1 894 LEU 894 894 894 LEU LEU A . n A 1 895 VAL 895 895 895 VAL VAL A . n A 1 896 LEU 896 896 896 LEU LEU A . n A 1 897 GLU 897 897 897 GLU GLU A . n A 1 898 LYS 898 898 898 LYS LYS A . n A 1 899 VAL 899 899 899 VAL VAL A . n A 1 900 ASN 900 900 900 ASN ASN A . n A 1 901 ASN 901 901 901 ASN ASN A . n A 1 902 CYS 902 902 902 CYS CYS A . n A 1 903 VAL 903 903 903 VAL VAL A . n A 1 904 ARG 904 904 904 ARG ARG A . n A 1 905 PRO 905 905 905 PRO PRO A . n A 1 906 SER 906 906 906 SER SER A . n A 1 907 LYS 907 907 907 LYS LYS A . n A 1 908 LEU 908 908 908 LEU LEU A . n A 1 909 HIS 909 909 909 HIS HIS A . n A 1 910 PRO 910 910 910 PRO PRO A . n A 1 911 ALA 911 911 911 ALA ALA A . n A 1 912 GLY 912 912 912 GLY GLY A . n A 1 913 TYR 913 913 913 TYR TYR A . n A 1 914 LEU 914 914 914 LEU LEU A . n A 1 915 THR 915 915 915 THR THR A . n A 1 916 SER 916 916 916 SER SER A . n A 1 917 ALA 917 917 917 ALA ALA A . n A 1 918 ALA 918 918 918 ALA ALA A . n A 1 919 HIS 919 919 919 HIS HIS A . n A 1 920 LYS 920 920 920 LYS LYS A . n A 1 921 ALA 921 921 921 ALA ALA A . n A 1 922 SER 922 922 922 SER SER A . n A 1 923 GLN 923 923 923 GLN GLN A . n A 1 924 SER 924 924 924 SER SER A . n A 1 925 LEU 925 925 925 LEU LEU A . n A 1 926 LEU 926 926 926 LEU LEU A . n A 1 927 ASP 927 927 927 ASP ASP A . n A 1 928 PRO 928 928 928 PRO PRO A . n A 1 929 LEU 929 929 929 LEU LEU A . n A 1 930 ASP 930 930 930 ASP ASP A . n A 1 931 LYS 931 931 931 LYS LYS A . n A 1 932 PHE 932 932 932 PHE PHE A . n A 1 933 ILE 933 933 933 ILE ILE A . n A 1 934 PHE 934 934 934 PHE PHE A . n A 1 935 ALA 935 935 935 ALA ALA A . n A 1 936 GLU 936 936 936 GLU GLU A . n A 1 937 ASN 937 937 937 ASN ASN A . n A 1 938 GLU 938 938 938 GLU GLU A . n A 1 939 TRP 939 939 939 TRP TRP A . n A 1 940 ILE 940 940 940 ILE ILE A . n A 1 941 GLY 941 941 941 GLY GLY A . n A 1 942 ALA 942 942 942 ALA ALA A . n A 1 943 GLN 943 943 943 GLN GLN A . n A 1 944 GLY 944 944 944 GLY GLY A . n A 1 945 GLN 945 945 945 GLN GLN A . n A 1 946 PHE 946 946 946 PHE PHE A . n A 1 947 GLY 947 947 947 GLY GLY A . n A 1 948 GLY 948 948 948 GLY GLY A . n A 1 949 ASP 949 949 949 ASP ASP A . n A 1 950 HIS 950 950 950 HIS HIS A . n A 1 951 PRO 951 951 951 PRO PRO A . n A 1 952 SER 952 952 952 SER SER A . n A 1 953 ALA 953 953 953 ALA ALA A . n A 1 954 ARG 954 954 954 ARG ARG A . n A 1 955 GLU 955 955 955 GLU GLU A . n A 1 956 ASP 956 956 956 ASP ASP A . n A 1 957 LEU 957 957 957 LEU LEU A . n A 1 958 ASP 958 958 958 ASP ASP A . n A 1 959 VAL 959 959 959 VAL VAL A . n A 1 960 SER 960 960 960 SER SER A . n A 1 961 VAL 961 961 961 VAL VAL A . n A 1 962 MET 962 962 962 MET MET A . n A 1 963 ARG 963 963 963 ARG ARG A . n A 1 964 ARG 964 964 964 ARG ARG A . n A 1 965 LEU 965 965 965 LEU LEU A . n A 1 966 THR 966 966 966 THR THR A . n A 1 967 LYS 967 967 967 LYS LYS A . n A 1 968 SER 968 968 968 SER SER A . n A 1 969 SER 969 969 969 SER SER A . n A 1 970 ALA 970 970 970 ALA ALA A . n A 1 971 LYS 971 971 971 LYS LYS A . n A 1 972 THR 972 972 972 THR THR A . n A 1 973 GLN 973 973 973 GLN GLN A . n A 1 974 ARG 974 974 974 ARG ARG A . n A 1 975 VAL 975 975 975 VAL VAL A . n A 1 976 GLY 976 976 976 GLY GLY A . n A 1 977 TYR 977 977 977 TYR TYR A . n A 1 978 VAL 978 978 978 VAL VAL A . n A 1 979 LEU 979 979 979 LEU LEU A . n A 1 980 HIS 980 980 980 HIS HIS A . n A 1 981 ARG 981 981 981 ARG ARG A . n A 1 982 THR 982 982 982 THR THR A . n A 1 983 ASN 983 983 983 ASN ASN A . n A 1 984 LEU 984 984 984 LEU LEU A . n A 1 985 MET 985 985 985 MET MET A . n A 1 986 GLN 986 986 986 GLN GLN A . n A 1 987 CYS 987 987 987 CYS CYS A . n A 1 988 GLY 988 988 988 GLY GLY A . n A 1 989 THR 989 989 989 THR THR A . n A 1 990 PRO 990 990 990 PRO PRO A . n A 1 991 GLU 991 991 991 GLU GLU A . n A 1 992 GLU 992 992 992 GLU GLU A . n A 1 993 HIS 993 993 993 HIS HIS A . n A 1 994 THR 994 994 994 THR THR A . n A 1 995 GLN 995 995 995 GLN GLN A . n A 1 996 LYS 996 996 996 LYS LYS A . n A 1 997 LEU 997 997 997 LEU LEU A . n A 1 998 ASP 998 998 998 ASP ASP A . n A 1 999 VAL 999 999 999 VAL VAL A . n A 1 1000 CYS 1000 1000 1000 CYS CYS A . n A 1 1001 HIS 1001 1001 1001 HIS HIS A . n A 1 1002 LEU 1002 1002 1002 LEU LEU A . n A 1 1003 LEU 1003 1003 1003 LEU LEU A . n A 1 1004 PRO 1004 1004 1004 PRO PRO A . n A 1 1005 ASN 1005 1005 1005 ASN ASN A . n A 1 1006 VAL 1006 1006 1006 VAL VAL A . n A 1 1007 ALA 1007 1007 1007 ALA ALA A . n A 1 1008 ARG 1008 1008 1008 ARG ARG A . n A 1 1009 CYS 1009 1009 1009 CYS CYS A . n A 1 1010 GLU 1010 1010 1010 GLU GLU A . n A 1 1011 ARG 1011 1011 1011 ARG ARG A . n A 1 1012 THR 1012 1012 1012 THR THR A . n A 1 1013 THR 1013 1013 1013 THR THR A . n A 1 1014 LEU 1014 1014 1014 LEU LEU A . n A 1 1015 THR 1015 1015 1015 THR THR A . n A 1 1016 PHE 1016 1016 1016 PHE PHE A . n A 1 1017 LEU 1017 1017 1017 LEU LEU A . n A 1 1018 GLN 1018 1018 1018 GLN GLN A . n A 1 1019 ASN 1019 1019 1019 ASN ASN A . n A 1 1020 LEU 1020 1020 1020 LEU LEU A . n A 1 1021 GLU 1021 1021 1021 GLU GLU A . n A 1 1022 HIS 1022 1022 1022 HIS HIS A . n A 1 1023 LEU 1023 1023 1023 LEU LEU A . n A 1 1024 ASP 1024 1024 1024 ASP ASP A . n A 1 1025 GLY 1025 1025 1025 GLY GLY A . n A 1 1026 MET 1026 1026 1026 MET MET A . n A 1 1027 VAL 1027 1027 1027 VAL VAL A . n A 1 1028 ALA 1028 1028 1028 ALA ALA A . n A 1 1029 PRO 1029 1029 1029 PRO PRO A . n A 1 1030 GLU 1030 1030 1030 GLU GLU A . n A 1 1031 VAL 1031 1031 1031 VAL VAL A . n A 1 1032 CYS 1032 1032 1032 CYS CYS A . n A 1 1033 PRO 1033 1033 1033 PRO PRO A . n A 1 1034 MET 1034 1034 1034 MET MET A . n A 1 1035 GLU 1035 1035 1035 GLU GLU A . n A 1 1036 THR 1036 1036 1036 THR THR A . n A 1 1037 ALA 1037 1037 1037 ALA ALA A . n A 1 1038 ALA 1038 1038 1038 ALA ALA A . n A 1 1039 TYR 1039 1039 1039 TYR TYR A . n A 1 1040 VAL 1040 1040 1040 VAL VAL A . n A 1 1041 SER 1041 1041 1041 SER SER A . n A 1 1042 SER 1042 1042 1042 SER SER A . n A 1 1043 HIS 1043 1043 1043 HIS HIS A . n A 1 1044 SER 1044 1044 1044 SER SER A . n A 1 1045 SER 1045 1045 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 2001 1 NAG NAG A . C 3 ZN 1 2004 1 ZN ZN A . D 4 GUL 1 2003 1 GUL GUL A . E 5 MPD 1 2002 1 MPD MPD A . F 6 HOH 1 2005 1 HOH WAT A . F 6 HOH 2 2006 2 HOH WAT A . F 6 HOH 3 2007 3 HOH WAT A . F 6 HOH 4 2008 4 HOH WAT A . F 6 HOH 5 2009 5 HOH WAT A . F 6 HOH 6 2010 6 HOH WAT A . F 6 HOH 7 2011 7 HOH WAT A . F 6 HOH 8 2012 8 HOH WAT A . F 6 HOH 9 2013 9 HOH WAT A . F 6 HOH 10 2014 10 HOH WAT A . F 6 HOH 11 2015 11 HOH WAT A . F 6 HOH 12 2016 12 HOH WAT A . F 6 HOH 13 2017 13 HOH WAT A . F 6 HOH 14 2018 14 HOH WAT A . F 6 HOH 15 2019 15 HOH WAT A . F 6 HOH 16 2020 16 HOH WAT A . F 6 HOH 17 2021 17 HOH WAT A . F 6 HOH 18 2022 18 HOH WAT A . F 6 HOH 19 2023 19 HOH WAT A . F 6 HOH 20 2024 20 HOH WAT A . F 6 HOH 21 2025 21 HOH WAT A . F 6 HOH 22 2026 22 HOH WAT A . F 6 HOH 23 2027 23 HOH WAT A . F 6 HOH 24 2028 24 HOH WAT A . F 6 HOH 25 2029 25 HOH WAT A . F 6 HOH 26 2030 26 HOH WAT A . F 6 HOH 27 2031 27 HOH WAT A . F 6 HOH 28 2032 28 HOH WAT A . F 6 HOH 29 2033 29 HOH WAT A . F 6 HOH 30 2034 30 HOH WAT A . F 6 HOH 31 2035 31 HOH WAT A . F 6 HOH 32 2036 32 HOH WAT A . F 6 HOH 33 2037 33 HOH WAT A . F 6 HOH 34 2038 34 HOH WAT A . F 6 HOH 35 2039 35 HOH WAT A . F 6 HOH 36 2040 36 HOH WAT A . F 6 HOH 37 2041 37 HOH WAT A . F 6 HOH 38 2042 38 HOH WAT A . F 6 HOH 39 2043 39 HOH WAT A . F 6 HOH 40 2044 40 HOH WAT A . F 6 HOH 41 2045 41 HOH WAT A . F 6 HOH 42 2046 42 HOH WAT A . F 6 HOH 43 2047 43 HOH WAT A . F 6 HOH 44 2048 44 HOH WAT A . F 6 HOH 45 2049 45 HOH WAT A . F 6 HOH 46 2050 46 HOH WAT A . F 6 HOH 47 2051 47 HOH WAT A . F 6 HOH 48 2052 48 HOH WAT A . F 6 HOH 49 2053 49 HOH WAT A . F 6 HOH 50 2054 50 HOH WAT A . F 6 HOH 51 2055 51 HOH WAT A . F 6 HOH 52 2056 52 HOH WAT A . F 6 HOH 53 2057 53 HOH WAT A . F 6 HOH 54 2058 54 HOH WAT A . F 6 HOH 55 2059 55 HOH WAT A . F 6 HOH 56 2060 56 HOH WAT A . F 6 HOH 57 2061 57 HOH WAT A . F 6 HOH 58 2062 58 HOH WAT A . F 6 HOH 59 2063 59 HOH WAT A . F 6 HOH 60 2064 60 HOH WAT A . F 6 HOH 61 2065 61 HOH WAT A . F 6 HOH 62 2066 62 HOH WAT A . F 6 HOH 63 2067 63 HOH WAT A . F 6 HOH 64 2068 64 HOH WAT A . F 6 HOH 65 2069 65 HOH WAT A . F 6 HOH 66 2070 66 HOH WAT A . F 6 HOH 67 2071 67 HOH WAT A . F 6 HOH 68 2072 68 HOH WAT A . F 6 HOH 69 2073 69 HOH WAT A . F 6 HOH 70 2074 70 HOH WAT A . F 6 HOH 71 2075 71 HOH WAT A . F 6 HOH 72 2076 72 HOH WAT A . F 6 HOH 73 2077 73 HOH WAT A . F 6 HOH 74 2078 74 HOH WAT A . F 6 HOH 75 2079 75 HOH WAT A . F 6 HOH 76 2080 76 HOH WAT A . F 6 HOH 77 2081 77 HOH WAT A . F 6 HOH 78 2082 78 HOH WAT A . F 6 HOH 79 2083 79 HOH WAT A . F 6 HOH 80 2084 80 HOH WAT A . F 6 HOH 81 2085 81 HOH WAT A . F 6 HOH 82 2086 82 HOH WAT A . F 6 HOH 83 2087 83 HOH WAT A . F 6 HOH 84 2088 84 HOH WAT A . F 6 HOH 85 2089 85 HOH WAT A . F 6 HOH 86 2090 86 HOH WAT A . F 6 HOH 87 2091 87 HOH WAT A . F 6 HOH 88 2092 88 HOH WAT A . F 6 HOH 89 2093 89 HOH WAT A . F 6 HOH 90 2094 90 HOH WAT A . F 6 HOH 91 2095 91 HOH WAT A . F 6 HOH 92 2096 92 HOH WAT A . F 6 HOH 93 2097 93 HOH WAT A . F 6 HOH 94 2098 94 HOH WAT A . F 6 HOH 95 2099 95 HOH WAT A . F 6 HOH 96 2100 96 HOH WAT A . F 6 HOH 97 2101 97 HOH WAT A . F 6 HOH 98 2102 98 HOH WAT A . F 6 HOH 99 2103 99 HOH WAT A . F 6 HOH 100 2104 100 HOH WAT A . F 6 HOH 101 2105 101 HOH WAT A . F 6 HOH 102 2106 102 HOH WAT A . F 6 HOH 103 2107 103 HOH WAT A . F 6 HOH 104 2108 104 HOH WAT A . F 6 HOH 105 2109 105 HOH WAT A . F 6 HOH 106 2110 106 HOH WAT A . F 6 HOH 107 2111 107 HOH WAT A . F 6 HOH 108 2112 108 HOH WAT A . F 6 HOH 109 2113 109 HOH WAT A . F 6 HOH 110 2114 110 HOH WAT A . F 6 HOH 111 2115 111 HOH WAT A . F 6 HOH 112 2116 112 HOH WAT A . F 6 HOH 113 2117 113 HOH WAT A . F 6 HOH 114 2118 114 HOH WAT A . F 6 HOH 115 2119 115 HOH WAT A . F 6 HOH 116 2120 116 HOH WAT A . F 6 HOH 117 2121 117 HOH WAT A . F 6 HOH 118 2122 118 HOH WAT A . F 6 HOH 119 2123 119 HOH WAT A . F 6 HOH 120 2124 120 HOH WAT A . F 6 HOH 121 2125 121 HOH WAT A . F 6 HOH 122 2126 122 HOH WAT A . F 6 HOH 123 2127 123 HOH WAT A . F 6 HOH 124 2128 124 HOH WAT A . F 6 HOH 125 2129 125 HOH WAT A . F 6 HOH 126 2130 126 HOH WAT A . F 6 HOH 127 2131 127 HOH WAT A . F 6 HOH 128 2132 128 HOH WAT A . F 6 HOH 129 2133 129 HOH WAT A . F 6 HOH 130 2134 130 HOH WAT A . F 6 HOH 131 2135 131 HOH WAT A . F 6 HOH 132 2136 132 HOH WAT A . F 6 HOH 133 2137 133 HOH WAT A . F 6 HOH 134 2138 134 HOH WAT A . F 6 HOH 135 2139 135 HOH WAT A . F 6 HOH 136 2140 136 HOH WAT A . F 6 HOH 137 2141 137 HOH WAT A . F 6 HOH 138 2142 138 HOH WAT A . F 6 HOH 139 2143 139 HOH WAT A . F 6 HOH 140 2144 140 HOH WAT A . F 6 HOH 141 2145 141 HOH WAT A . F 6 HOH 142 2146 142 HOH WAT A . F 6 HOH 143 2147 143 HOH WAT A . F 6 HOH 144 2148 144 HOH WAT A . F 6 HOH 145 2149 145 HOH WAT A . F 6 HOH 146 2150 146 HOH WAT A . F 6 HOH 147 2151 147 HOH WAT A . F 6 HOH 148 2152 148 HOH WAT A . F 6 HOH 149 2153 149 HOH WAT A . F 6 HOH 150 2154 150 HOH WAT A . F 6 HOH 151 2155 151 HOH WAT A . F 6 HOH 152 2156 152 HOH WAT A . F 6 HOH 153 2157 153 HOH WAT A . F 6 HOH 154 2158 154 HOH WAT A . F 6 HOH 155 2159 155 HOH WAT A . F 6 HOH 156 2160 156 HOH WAT A . F 6 HOH 157 2161 157 HOH WAT A . F 6 HOH 158 2162 158 HOH WAT A . F 6 HOH 159 2163 159 HOH WAT A . F 6 HOH 160 2164 160 HOH WAT A . F 6 HOH 161 2165 161 HOH WAT A . F 6 HOH 162 2166 162 HOH WAT A . F 6 HOH 163 2167 163 HOH WAT A . F 6 HOH 164 2168 164 HOH WAT A . F 6 HOH 165 2169 165 HOH WAT A . F 6 HOH 166 2170 166 HOH WAT A . F 6 HOH 167 2171 167 HOH WAT A . F 6 HOH 168 2172 168 HOH WAT A . F 6 HOH 169 2173 169 HOH WAT A . F 6 HOH 170 2174 170 HOH WAT A . F 6 HOH 171 2175 171 HOH WAT A . F 6 HOH 172 2176 172 HOH WAT A . F 6 HOH 173 2177 173 HOH WAT A . F 6 HOH 174 2178 174 HOH WAT A . F 6 HOH 175 2179 175 HOH WAT A . F 6 HOH 176 2180 176 HOH WAT A . F 6 HOH 177 2181 177 HOH WAT A . F 6 HOH 178 2182 178 HOH WAT A . F 6 HOH 179 2183 179 HOH WAT A . F 6 HOH 180 2184 180 HOH WAT A . F 6 HOH 181 2185 181 HOH WAT A . F 6 HOH 182 2186 182 HOH WAT A . F 6 HOH 183 2187 183 HOH WAT A . F 6 HOH 184 2188 184 HOH WAT A . F 6 HOH 185 2189 185 HOH WAT A . F 6 HOH 186 2190 186 HOH WAT A . F 6 HOH 187 2191 187 HOH WAT A . F 6 HOH 188 2192 188 HOH WAT A . F 6 HOH 189 2193 189 HOH WAT A . F 6 HOH 190 2194 190 HOH WAT A . F 6 HOH 191 2195 191 HOH WAT A . F 6 HOH 192 2196 192 HOH WAT A . F 6 HOH 193 2197 193 HOH WAT A . F 6 HOH 194 2198 194 HOH WAT A . F 6 HOH 195 2199 195 HOH WAT A . F 6 HOH 196 2200 196 HOH WAT A . F 6 HOH 197 2201 197 HOH WAT A . F 6 HOH 198 2202 198 HOH WAT A . F 6 HOH 199 2203 199 HOH WAT A . F 6 HOH 200 2204 200 HOH WAT A . F 6 HOH 201 2205 201 HOH WAT A . F 6 HOH 202 2206 202 HOH WAT A . F 6 HOH 203 2207 203 HOH WAT A . F 6 HOH 204 2208 204 HOH WAT A . F 6 HOH 205 2209 205 HOH WAT A . F 6 HOH 206 2210 206 HOH WAT A . F 6 HOH 207 2211 207 HOH WAT A . F 6 HOH 208 2212 208 HOH WAT A . F 6 HOH 209 2213 209 HOH WAT A . F 6 HOH 210 2214 210 HOH WAT A . F 6 HOH 211 2215 211 HOH WAT A . F 6 HOH 212 2216 212 HOH WAT A . F 6 HOH 213 2217 213 HOH WAT A . F 6 HOH 214 2218 214 HOH WAT A . F 6 HOH 215 2219 215 HOH WAT A . F 6 HOH 216 2220 216 HOH WAT A . F 6 HOH 217 2221 217 HOH WAT A . F 6 HOH 218 2222 218 HOH WAT A . F 6 HOH 219 2223 219 HOH WAT A . F 6 HOH 220 2224 220 HOH WAT A . F 6 HOH 221 2225 221 HOH WAT A . F 6 HOH 222 2226 222 HOH WAT A . F 6 HOH 223 2227 223 HOH WAT A . F 6 HOH 224 2228 224 HOH WAT A . F 6 HOH 225 2229 225 HOH WAT A . F 6 HOH 226 2230 226 HOH WAT A . F 6 HOH 227 2231 227 HOH WAT A . F 6 HOH 228 2232 228 HOH WAT A . F 6 HOH 229 2233 229 HOH WAT A . F 6 HOH 230 2234 230 HOH WAT A . F 6 HOH 231 2235 231 HOH WAT A . F 6 HOH 232 2236 232 HOH WAT A . F 6 HOH 233 2237 233 HOH WAT A . F 6 HOH 234 2238 234 HOH WAT A . F 6 HOH 235 2239 235 HOH WAT A . F 6 HOH 236 2240 236 HOH WAT A . F 6 HOH 237 2241 237 HOH WAT A . F 6 HOH 238 2242 238 HOH WAT A . F 6 HOH 239 2243 239 HOH WAT A . F 6 HOH 240 2244 240 HOH WAT A . F 6 HOH 241 2245 241 HOH WAT A . F 6 HOH 242 2246 242 HOH WAT A . F 6 HOH 243 2247 243 HOH WAT A . F 6 HOH 244 2248 244 HOH WAT A . F 6 HOH 245 2249 245 HOH WAT A . F 6 HOH 246 2250 246 HOH WAT A . F 6 HOH 247 2251 247 HOH WAT A . F 6 HOH 248 2252 248 HOH WAT A . F 6 HOH 249 2253 249 HOH WAT A . F 6 HOH 250 2254 250 HOH WAT A . F 6 HOH 251 2255 251 HOH WAT A . F 6 HOH 252 2256 252 HOH WAT A . F 6 HOH 253 2257 253 HOH WAT A . F 6 HOH 254 2258 254 HOH WAT A . F 6 HOH 255 2259 255 HOH WAT A . F 6 HOH 256 2260 256 HOH WAT A . F 6 HOH 257 2261 257 HOH WAT A . F 6 HOH 258 2262 258 HOH WAT A . F 6 HOH 259 2263 259 HOH WAT A . F 6 HOH 260 2264 260 HOH WAT A . F 6 HOH 261 2265 261 HOH WAT A . F 6 HOH 262 2266 262 HOH WAT A . F 6 HOH 263 2267 263 HOH WAT A . F 6 HOH 264 2268 264 HOH WAT A . F 6 HOH 265 2269 265 HOH WAT A . F 6 HOH 266 2270 266 HOH WAT A . F 6 HOH 267 2271 267 HOH WAT A . F 6 HOH 268 2272 268 HOH WAT A . F 6 HOH 269 2273 269 HOH WAT A . F 6 HOH 270 2274 270 HOH WAT A . F 6 HOH 271 2275 271 HOH WAT A . F 6 HOH 272 2276 272 HOH WAT A . F 6 HOH 273 2277 273 HOH WAT A . F 6 HOH 274 2278 274 HOH WAT A . F 6 HOH 275 2279 275 HOH WAT A . F 6 HOH 276 2280 276 HOH WAT A . F 6 HOH 277 2281 277 HOH WAT A . F 6 HOH 278 2282 278 HOH WAT A . F 6 HOH 279 2283 279 HOH WAT A . F 6 HOH 280 2284 280 HOH WAT A . F 6 HOH 281 2285 281 HOH WAT A . F 6 HOH 282 2286 282 HOH WAT A . F 6 HOH 283 2287 283 HOH WAT A . F 6 HOH 284 2288 284 HOH WAT A . F 6 HOH 285 2289 285 HOH WAT A . F 6 HOH 286 2290 286 HOH WAT A . F 6 HOH 287 2291 287 HOH WAT A . F 6 HOH 288 2292 288 HOH WAT A . F 6 HOH 289 2293 289 HOH WAT A . F 6 HOH 290 2294 290 HOH WAT A . F 6 HOH 291 2295 291 HOH WAT A . F 6 HOH 292 2296 292 HOH WAT A . F 6 HOH 293 2297 293 HOH WAT A . F 6 HOH 294 2298 294 HOH WAT A . F 6 HOH 295 2299 295 HOH WAT A . F 6 HOH 296 2300 296 HOH WAT A . F 6 HOH 297 2301 297 HOH WAT A . F 6 HOH 298 2302 298 HOH WAT A . F 6 HOH 299 2303 299 HOH WAT A . F 6 HOH 300 2304 300 HOH WAT A . F 6 HOH 301 2305 301 HOH WAT A . F 6 HOH 302 2306 302 HOH WAT A . F 6 HOH 303 2307 303 HOH WAT A . F 6 HOH 304 2308 304 HOH WAT A . F 6 HOH 305 2309 305 HOH WAT A . F 6 HOH 306 2310 306 HOH WAT A . F 6 HOH 307 2311 307 HOH WAT A . F 6 HOH 308 2312 308 HOH WAT A . F 6 HOH 309 2313 309 HOH WAT A . F 6 HOH 310 2314 310 HOH WAT A . F 6 HOH 311 2315 311 HOH WAT A . F 6 HOH 312 2316 312 HOH WAT A . F 6 HOH 313 2317 313 HOH WAT A . F 6 HOH 314 2318 314 HOH WAT A . F 6 HOH 315 2319 315 HOH WAT A . F 6 HOH 316 2320 316 HOH WAT A . F 6 HOH 317 2321 317 HOH WAT A . F 6 HOH 318 2322 318 HOH WAT A . F 6 HOH 319 2323 319 HOH WAT A . F 6 HOH 320 2324 320 HOH WAT A . F 6 HOH 321 2325 321 HOH WAT A . F 6 HOH 322 2326 322 HOH WAT A . F 6 HOH 323 2327 323 HOH WAT A . F 6 HOH 324 2328 324 HOH WAT A . F 6 HOH 325 2329 325 HOH WAT A . F 6 HOH 326 2330 326 HOH WAT A . F 6 HOH 327 2331 327 HOH WAT A . F 6 HOH 328 2332 328 HOH WAT A . F 6 HOH 329 2333 329 HOH WAT A . F 6 HOH 330 2334 330 HOH WAT A . F 6 HOH 331 2335 331 HOH WAT A . F 6 HOH 332 2336 332 HOH WAT A . F 6 HOH 333 2337 333 HOH WAT A . F 6 HOH 334 2338 334 HOH WAT A . F 6 HOH 335 2339 335 HOH WAT A . F 6 HOH 336 2340 336 HOH WAT A . F 6 HOH 337 2341 337 HOH WAT A . F 6 HOH 338 2342 338 HOH WAT A . F 6 HOH 339 2343 339 HOH WAT A . F 6 HOH 340 2344 340 HOH WAT A . F 6 HOH 341 2345 341 HOH WAT A . F 6 HOH 342 2346 342 HOH WAT A . F 6 HOH 343 2347 343 HOH WAT A . F 6 HOH 344 2348 344 HOH WAT A . F 6 HOH 345 2349 345 HOH WAT A . F 6 HOH 346 2350 346 HOH WAT A . F 6 HOH 347 2351 347 HOH WAT A . F 6 HOH 348 2352 348 HOH WAT A . F 6 HOH 349 2353 349 HOH WAT A . F 6 HOH 350 2354 350 HOH WAT A . F 6 HOH 351 2355 351 HOH WAT A . F 6 HOH 352 2356 352 HOH WAT A . F 6 HOH 353 2357 353 HOH WAT A . F 6 HOH 354 2358 354 HOH WAT A . F 6 HOH 355 2359 355 HOH WAT A . F 6 HOH 356 2360 356 HOH WAT A . F 6 HOH 357 2361 357 HOH WAT A . F 6 HOH 358 2362 358 HOH WAT A . F 6 HOH 359 2363 359 HOH WAT A . F 6 HOH 360 2364 360 HOH WAT A . F 6 HOH 361 2365 361 HOH WAT A . F 6 HOH 362 2366 362 HOH WAT A . F 6 HOH 363 2367 363 HOH WAT A . F 6 HOH 364 2368 364 HOH WAT A . F 6 HOH 365 2369 365 HOH WAT A . F 6 HOH 366 2370 366 HOH WAT A . F 6 HOH 367 2371 367 HOH WAT A . F 6 HOH 368 2372 368 HOH WAT A . F 6 HOH 369 2373 369 HOH WAT A . F 6 HOH 370 2374 370 HOH WAT A . F 6 HOH 371 2375 371 HOH WAT A . F 6 HOH 372 2376 372 HOH WAT A . F 6 HOH 373 2377 373 HOH WAT A . F 6 HOH 374 2378 374 HOH WAT A . F 6 HOH 375 2379 375 HOH WAT A . F 6 HOH 376 2380 376 HOH WAT A . F 6 HOH 377 2381 377 HOH WAT A . F 6 HOH 378 2382 378 HOH WAT A . F 6 HOH 379 2383 379 HOH WAT A . F 6 HOH 380 2384 380 HOH WAT A . F 6 HOH 381 2385 381 HOH WAT A . F 6 HOH 382 2386 382 HOH WAT A . F 6 HOH 383 2387 383 HOH WAT A . F 6 HOH 384 2388 384 HOH WAT A . F 6 HOH 385 2389 385 HOH WAT A . F 6 HOH 386 2390 386 HOH WAT A . F 6 HOH 387 2391 387 HOH WAT A . F 6 HOH 388 2392 388 HOH WAT A . F 6 HOH 389 2393 389 HOH WAT A . F 6 HOH 390 2394 390 HOH WAT A . F 6 HOH 391 2395 391 HOH WAT A . F 6 HOH 392 2396 392 HOH WAT A . F 6 HOH 393 2397 393 HOH WAT A . F 6 HOH 394 2398 394 HOH WAT A . F 6 HOH 395 2399 395 HOH WAT A . F 6 HOH 396 2400 396 HOH WAT A . F 6 HOH 397 2401 397 HOH WAT A . F 6 HOH 398 2402 398 HOH WAT A . F 6 HOH 399 2403 399 HOH WAT A . F 6 HOH 400 2404 400 HOH WAT A . F 6 HOH 401 2405 401 HOH WAT A . F 6 HOH 402 2406 402 HOH WAT A . F 6 HOH 403 2407 403 HOH WAT A . F 6 HOH 404 2408 404 HOH WAT A . F 6 HOH 405 2409 405 HOH WAT A . F 6 HOH 406 2410 406 HOH WAT A . F 6 HOH 407 2411 407 HOH WAT A . F 6 HOH 408 2412 408 HOH WAT A . F 6 HOH 409 2413 409 HOH WAT A . F 6 HOH 410 2414 410 HOH WAT A . F 6 HOH 411 2415 411 HOH WAT A . F 6 HOH 412 2416 412 HOH WAT A . F 6 HOH 413 2417 413 HOH WAT A . F 6 HOH 414 2418 414 HOH WAT A . F 6 HOH 415 2419 415 HOH WAT A . F 6 HOH 416 2420 416 HOH WAT A . F 6 HOH 417 2421 417 HOH WAT A . F 6 HOH 418 2422 418 HOH WAT A . F 6 HOH 419 2423 419 HOH WAT A . F 6 HOH 420 2424 420 HOH WAT A . F 6 HOH 421 2425 421 HOH WAT A . F 6 HOH 422 2426 422 HOH WAT A . F 6 HOH 423 2427 423 HOH WAT A . F 6 HOH 424 2428 424 HOH WAT A . F 6 HOH 425 2429 425 HOH WAT A . F 6 HOH 426 2430 426 HOH WAT A . F 6 HOH 427 2431 427 HOH WAT A . F 6 HOH 428 2432 428 HOH WAT A . F 6 HOH 429 2433 429 HOH WAT A . F 6 HOH 430 2434 430 HOH WAT A . F 6 HOH 431 2435 431 HOH WAT A . F 6 HOH 432 2436 432 HOH WAT A . F 6 HOH 433 2437 433 HOH WAT A . F 6 HOH 434 2438 434 HOH WAT A . F 6 HOH 435 2439 435 HOH WAT A . F 6 HOH 436 2440 436 HOH WAT A . F 6 HOH 437 2441 437 HOH WAT A . F 6 HOH 438 2442 438 HOH WAT A . F 6 HOH 439 2443 439 HOH WAT A . F 6 HOH 440 2444 440 HOH WAT A . F 6 HOH 441 2445 441 HOH WAT A . F 6 HOH 442 2446 442 HOH WAT A . F 6 HOH 443 2447 443 HOH WAT A . F 6 HOH 444 2448 444 HOH WAT A . F 6 HOH 445 2449 445 HOH WAT A . F 6 HOH 446 2450 446 HOH WAT A . F 6 HOH 447 2451 447 HOH WAT A . F 6 HOH 448 2452 448 HOH WAT A . F 6 HOH 449 2453 449 HOH WAT A . F 6 HOH 450 2454 450 HOH WAT A . F 6 HOH 451 2455 451 HOH WAT A . F 6 HOH 452 2456 452 HOH WAT A . F 6 HOH 453 2457 453 HOH WAT A . F 6 HOH 454 2458 454 HOH WAT A . F 6 HOH 455 2459 455 HOH WAT A . F 6 HOH 456 2460 456 HOH WAT A . F 6 HOH 457 2461 457 HOH WAT A . F 6 HOH 458 2462 458 HOH WAT A . F 6 HOH 459 2463 459 HOH WAT A . F 6 HOH 460 2464 460 HOH WAT A . F 6 HOH 461 2465 461 HOH WAT A . F 6 HOH 462 2466 462 HOH WAT A . F 6 HOH 463 2467 463 HOH WAT A . F 6 HOH 464 2468 464 HOH WAT A . F 6 HOH 465 2469 465 HOH WAT A . F 6 HOH 466 2470 466 HOH WAT A . F 6 HOH 467 2471 467 HOH WAT A . F 6 HOH 468 2472 468 HOH WAT A . F 6 HOH 469 2473 469 HOH WAT A . F 6 HOH 470 2474 470 HOH WAT A . F 6 HOH 471 2475 471 HOH WAT A . F 6 HOH 472 2476 472 HOH WAT A . F 6 HOH 473 2477 473 HOH WAT A . F 6 HOH 474 2478 474 HOH WAT A . F 6 HOH 475 2479 475 HOH WAT A . F 6 HOH 476 2480 476 HOH WAT A . F 6 HOH 477 2481 477 HOH WAT A . F 6 HOH 478 2482 478 HOH WAT A . F 6 HOH 479 2483 479 HOH WAT A . F 6 HOH 480 2484 480 HOH WAT A . F 6 HOH 481 2485 481 HOH WAT A . F 6 HOH 482 2486 482 HOH WAT A . F 6 HOH 483 2487 483 HOH WAT A . F 6 HOH 484 2488 484 HOH WAT A . F 6 HOH 485 2489 485 HOH WAT A . F 6 HOH 486 2490 486 HOH WAT A . F 6 HOH 487 2491 487 HOH WAT A . F 6 HOH 488 2492 488 HOH WAT A . F 6 HOH 489 2493 489 HOH WAT A . F 6 HOH 490 2494 490 HOH WAT A . F 6 HOH 491 2495 491 HOH WAT A . F 6 HOH 492 2496 492 HOH WAT A . F 6 HOH 493 2497 493 HOH WAT A . F 6 HOH 494 2498 494 HOH WAT A . F 6 HOH 495 2499 495 HOH WAT A . F 6 HOH 496 2500 496 HOH WAT A . F 6 HOH 497 2501 497 HOH WAT A . F 6 HOH 498 2502 498 HOH WAT A . F 6 HOH 499 2503 499 HOH WAT A . F 6 HOH 500 2504 500 HOH WAT A . F 6 HOH 501 2505 501 HOH WAT A . F 6 HOH 502 2506 502 HOH WAT A . F 6 HOH 503 2507 503 HOH WAT A . F 6 HOH 504 2508 504 HOH WAT A . F 6 HOH 505 2509 505 HOH WAT A . F 6 HOH 506 2510 506 HOH WAT A . F 6 HOH 507 2511 507 HOH WAT A . F 6 HOH 508 2512 508 HOH WAT A . F 6 HOH 509 2513 509 HOH WAT A . F 6 HOH 510 2514 510 HOH WAT A . F 6 HOH 511 2515 511 HOH WAT A . F 6 HOH 512 2516 512 HOH WAT A . F 6 HOH 513 2517 513 HOH WAT A . F 6 HOH 514 2518 514 HOH WAT A . F 6 HOH 515 2519 515 HOH WAT A . F 6 HOH 516 2520 516 HOH WAT A . F 6 HOH 517 2521 517 HOH WAT A . F 6 HOH 518 2522 518 HOH WAT A . F 6 HOH 519 2523 519 HOH WAT A . F 6 HOH 520 2524 520 HOH WAT A . F 6 HOH 521 2525 521 HOH WAT A . F 6 HOH 522 2526 522 HOH WAT A . F 6 HOH 523 2527 523 HOH WAT A . F 6 HOH 524 2528 524 HOH WAT A . F 6 HOH 525 2529 525 HOH WAT A . F 6 HOH 526 2530 526 HOH WAT A . F 6 HOH 527 2531 527 HOH WAT A . F 6 HOH 528 2532 528 HOH WAT A . F 6 HOH 529 2533 529 HOH WAT A . F 6 HOH 530 2534 530 HOH WAT A . F 6 HOH 531 2535 531 HOH WAT A . F 6 HOH 532 2536 532 HOH WAT A . F 6 HOH 533 2537 533 HOH WAT A . F 6 HOH 534 2538 534 HOH WAT A . F 6 HOH 535 2539 535 HOH WAT A . F 6 HOH 536 2540 536 HOH WAT A . F 6 HOH 537 2541 537 HOH WAT A . F 6 HOH 538 2542 538 HOH WAT A . F 6 HOH 539 2543 539 HOH WAT A . F 6 HOH 540 2544 540 HOH WAT A . F 6 HOH 541 2545 541 HOH WAT A . F 6 HOH 542 2546 542 HOH WAT A . F 6 HOH 543 2547 543 HOH WAT A . F 6 HOH 544 2548 544 HOH WAT A . F 6 HOH 545 2549 545 HOH WAT A . F 6 HOH 546 2550 546 HOH WAT A . F 6 HOH 547 2551 547 HOH WAT A . F 6 HOH 548 2552 548 HOH WAT A . F 6 HOH 549 2553 549 HOH WAT A . F 6 HOH 550 2554 550 HOH WAT A . F 6 HOH 551 2555 551 HOH WAT A . F 6 HOH 552 2556 552 HOH WAT A . F 6 HOH 553 2557 553 HOH WAT A . F 6 HOH 554 2558 554 HOH WAT A . F 6 HOH 555 2559 555 HOH WAT A . F 6 HOH 556 2560 556 HOH WAT A . F 6 HOH 557 2561 557 HOH WAT A . F 6 HOH 558 2562 558 HOH WAT A . F 6 HOH 559 2563 559 HOH WAT A . F 6 HOH 560 2564 560 HOH WAT A . F 6 HOH 561 2565 561 HOH WAT A . F 6 HOH 562 2566 562 HOH WAT A . F 6 HOH 563 2567 563 HOH WAT A . F 6 HOH 564 2568 564 HOH WAT A . F 6 HOH 565 2569 565 HOH WAT A . F 6 HOH 566 2570 566 HOH WAT A . F 6 HOH 567 2571 567 HOH WAT A . F 6 HOH 568 2572 568 HOH WAT A . F 6 HOH 569 2573 569 HOH WAT A . F 6 HOH 570 2574 570 HOH WAT A . F 6 HOH 571 2575 571 HOH WAT A . F 6 HOH 572 2576 572 HOH WAT A . F 6 HOH 573 2577 573 HOH WAT A . F 6 HOH 574 2578 574 HOH WAT A . F 6 HOH 575 2579 575 HOH WAT A . F 6 HOH 576 2580 576 HOH WAT A . F 6 HOH 577 2581 577 HOH WAT A . F 6 HOH 578 2582 578 HOH WAT A . F 6 HOH 579 2583 579 HOH WAT A . F 6 HOH 580 2584 580 HOH WAT A . F 6 HOH 581 2585 581 HOH WAT A . F 6 HOH 582 2586 582 HOH WAT A . F 6 HOH 583 2587 583 HOH WAT A . F 6 HOH 584 2588 584 HOH WAT A . F 6 HOH 585 2589 585 HOH WAT A . F 6 HOH 586 2590 586 HOH WAT A . F 6 HOH 587 2591 587 HOH WAT A . F 6 HOH 588 2592 588 HOH WAT A . F 6 HOH 589 2593 589 HOH WAT A . F 6 HOH 590 2594 590 HOH WAT A . F 6 HOH 591 2595 591 HOH WAT A . F 6 HOH 592 2596 592 HOH WAT A . F 6 HOH 593 2597 593 HOH WAT A . F 6 HOH 594 2598 594 HOH WAT A . F 6 HOH 595 2599 595 HOH WAT A . F 6 HOH 596 2600 596 HOH WAT A . F 6 HOH 597 2601 597 HOH WAT A . F 6 HOH 598 2602 598 HOH WAT A . F 6 HOH 599 2603 599 HOH WAT A . F 6 HOH 600 2604 600 HOH WAT A . F 6 HOH 601 2605 601 HOH WAT A . F 6 HOH 602 2606 602 HOH WAT A . F 6 HOH 603 2607 603 HOH WAT A . F 6 HOH 604 2608 604 HOH WAT A . F 6 HOH 605 2609 605 HOH WAT A . F 6 HOH 606 2610 606 HOH WAT A . F 6 HOH 607 2611 607 HOH WAT A . F 6 HOH 608 2612 608 HOH WAT A . F 6 HOH 609 2613 609 HOH WAT A . F 6 HOH 610 2614 610 HOH WAT A . F 6 HOH 611 2615 611 HOH WAT A . F 6 HOH 612 2616 612 HOH WAT A . F 6 HOH 613 2617 613 HOH WAT A . F 6 HOH 614 2618 614 HOH WAT A . F 6 HOH 615 2619 615 HOH WAT A . F 6 HOH 616 2620 616 HOH WAT A . F 6 HOH 617 2621 617 HOH WAT A . F 6 HOH 618 2622 618 HOH WAT A . F 6 HOH 619 2623 619 HOH WAT A . F 6 HOH 620 2624 620 HOH WAT A . F 6 HOH 621 2625 621 HOH WAT A . F 6 HOH 622 2626 622 HOH WAT A . F 6 HOH 623 2627 623 HOH WAT A . F 6 HOH 624 2628 624 HOH WAT A . F 6 HOH 625 2629 625 HOH WAT A . F 6 HOH 626 2630 626 HOH WAT A . F 6 HOH 627 2631 627 HOH WAT A . F 6 HOH 628 2632 628 HOH WAT A . F 6 HOH 629 2633 629 HOH WAT A . F 6 HOH 630 2634 630 HOH WAT A . F 6 HOH 631 2635 631 HOH WAT A . F 6 HOH 632 2636 632 HOH WAT A . F 6 HOH 633 2637 633 HOH WAT A . F 6 HOH 634 2638 634 HOH WAT A . F 6 HOH 635 2639 635 HOH WAT A . F 6 HOH 636 2640 636 HOH WAT A . F 6 HOH 637 2641 637 HOH WAT A . F 6 HOH 638 2642 638 HOH WAT A . F 6 HOH 639 2643 639 HOH WAT A . F 6 HOH 640 2644 640 HOH WAT A . F 6 HOH 641 2645 641 HOH WAT A . F 6 HOH 642 2646 642 HOH WAT A . F 6 HOH 643 2647 643 HOH WAT A . F 6 HOH 644 2648 644 HOH WAT A . F 6 HOH 645 2649 645 HOH WAT A . F 6 HOH 646 2650 646 HOH WAT A . F 6 HOH 647 2651 647 HOH WAT A . F 6 HOH 648 2652 648 HOH WAT A . F 6 HOH 649 2653 649 HOH WAT A . F 6 HOH 650 2654 650 HOH WAT A . F 6 HOH 651 2655 651 HOH WAT A . F 6 HOH 652 2656 652 HOH WAT A . F 6 HOH 653 2657 653 HOH WAT A . F 6 HOH 654 2658 654 HOH WAT A . F 6 HOH 655 2659 655 HOH WAT A . F 6 HOH 656 2660 656 HOH WAT A . F 6 HOH 657 2661 657 HOH WAT A . F 6 HOH 658 2662 658 HOH WAT A . F 6 HOH 659 2663 659 HOH WAT A . F 6 HOH 660 2664 660 HOH WAT A . F 6 HOH 661 2665 661 HOH WAT A . F 6 HOH 662 2666 662 HOH WAT A . F 6 HOH 663 2667 663 HOH WAT A . F 6 HOH 664 2668 664 HOH WAT A . F 6 HOH 665 2669 665 HOH WAT A . F 6 HOH 666 2670 666 HOH WAT A . F 6 HOH 667 2671 667 HOH WAT A . F 6 HOH 668 2672 668 HOH WAT A . F 6 HOH 669 2673 669 HOH WAT A . F 6 HOH 670 2674 670 HOH WAT A . F 6 HOH 671 2675 671 HOH WAT A . F 6 HOH 672 2676 672 HOH WAT A . F 6 HOH 673 2677 673 HOH WAT A . F 6 HOH 674 2678 674 HOH WAT A . F 6 HOH 675 2679 675 HOH WAT A . F 6 HOH 676 2680 676 HOH WAT A . F 6 HOH 677 2681 677 HOH WAT A . F 6 HOH 678 2682 678 HOH WAT A . F 6 HOH 679 2683 679 HOH WAT A . F 6 HOH 680 2684 680 HOH WAT A . F 6 HOH 681 2685 681 HOH WAT A . F 6 HOH 682 2686 682 HOH WAT A . F 6 HOH 683 2687 683 HOH WAT A . F 6 HOH 684 2688 684 HOH WAT A . F 6 HOH 685 2689 685 HOH WAT A . F 6 HOH 686 2690 686 HOH WAT A . F 6 HOH 687 2691 687 HOH WAT A . F 6 HOH 688 2692 688 HOH WAT A . F 6 HOH 689 2693 689 HOH WAT A . F 6 HOH 690 2694 690 HOH WAT A . F 6 HOH 691 2695 691 HOH WAT A . F 6 HOH 692 2696 692 HOH WAT A . F 6 HOH 693 2697 693 HOH WAT A . F 6 HOH 694 2698 694 HOH WAT A . F 6 HOH 695 2699 695 HOH WAT A . F 6 HOH 696 2700 696 HOH WAT A . F 6 HOH 697 2701 697 HOH WAT A . F 6 HOH 698 2702 698 HOH WAT A . F 6 HOH 699 2703 699 HOH WAT A . F 6 HOH 700 2704 700 HOH WAT A . F 6 HOH 701 2705 701 HOH WAT A . F 6 HOH 702 2706 702 HOH WAT A . F 6 HOH 703 2707 703 HOH WAT A . F 6 HOH 704 2708 704 HOH WAT A . F 6 HOH 705 2709 705 HOH WAT A . F 6 HOH 706 2710 706 HOH WAT A . F 6 HOH 707 2711 707 HOH WAT A . F 6 HOH 708 2712 708 HOH WAT A . F 6 HOH 709 2713 709 HOH WAT A . F 6 HOH 710 2714 710 HOH WAT A . F 6 HOH 711 2715 711 HOH WAT A . F 6 HOH 712 2716 712 HOH WAT A . F 6 HOH 713 2717 713 HOH WAT A . F 6 HOH 714 2718 714 HOH WAT A . F 6 HOH 715 2719 715 HOH WAT A . F 6 HOH 716 2720 716 HOH WAT A . F 6 HOH 717 2721 717 HOH WAT A . F 6 HOH 718 2722 718 HOH WAT A . F 6 HOH 719 2723 719 HOH WAT A . F 6 HOH 720 2724 720 HOH WAT A . F 6 HOH 721 2725 721 HOH WAT A . F 6 HOH 722 2726 722 HOH WAT A . F 6 HOH 723 2727 723 HOH WAT A . F 6 HOH 724 2728 724 HOH WAT A . F 6 HOH 725 2729 725 HOH WAT A . F 6 HOH 726 2730 726 HOH WAT A . F 6 HOH 727 2731 727 HOH WAT A . F 6 HOH 728 2732 728 HOH WAT A . F 6 HOH 729 2733 729 HOH WAT A . F 6 HOH 730 2734 730 HOH WAT A . F 6 HOH 731 2735 731 HOH WAT A . F 6 HOH 732 2736 732 HOH WAT A . F 6 HOH 733 2737 733 HOH WAT A . F 6 HOH 734 2738 734 HOH WAT A . F 6 HOH 735 2739 735 HOH WAT A . F 6 HOH 736 2740 736 HOH WAT A . F 6 HOH 737 2741 737 HOH WAT A . F 6 HOH 738 2742 738 HOH WAT A . F 6 HOH 739 2743 739 HOH WAT A . F 6 HOH 740 2744 740 HOH WAT A . F 6 HOH 741 2745 741 HOH WAT A . F 6 HOH 742 2746 742 HOH WAT A . F 6 HOH 743 2747 743 HOH WAT A . F 6 HOH 744 2748 744 HOH WAT A . F 6 HOH 745 2749 745 HOH WAT A . F 6 HOH 746 2750 746 HOH WAT A . F 6 HOH 747 2751 747 HOH WAT A . F 6 HOH 748 2752 748 HOH WAT A . F 6 HOH 749 2753 749 HOH WAT A . F 6 HOH 750 2754 750 HOH WAT A . F 6 HOH 751 2755 751 HOH WAT A . F 6 HOH 752 2756 752 HOH WAT A . F 6 HOH 753 2757 753 HOH WAT A . F 6 HOH 754 2758 754 HOH WAT A . F 6 HOH 755 2759 755 HOH WAT A . F 6 HOH 756 2760 756 HOH WAT A . F 6 HOH 757 2761 757 HOH WAT A . F 6 HOH 758 2762 758 HOH WAT A . F 6 HOH 759 2763 759 HOH WAT A . F 6 HOH 760 2764 760 HOH WAT A . F 6 HOH 761 2765 761 HOH WAT A . F 6 HOH 762 2766 762 HOH WAT A . F 6 HOH 763 2767 763 HOH WAT A . F 6 HOH 764 2768 764 HOH WAT A . F 6 HOH 765 2769 765 HOH WAT A . F 6 HOH 766 2770 766 HOH WAT A . F 6 HOH 767 2771 767 HOH WAT A . F 6 HOH 768 2772 768 HOH WAT A . F 6 HOH 769 2773 769 HOH WAT A . F 6 HOH 770 2774 770 HOH WAT A . F 6 HOH 771 2775 771 HOH WAT A . F 6 HOH 772 2776 772 HOH WAT A . F 6 HOH 773 2777 773 HOH WAT A . F 6 HOH 774 2778 774 HOH WAT A . F 6 HOH 775 2779 775 HOH WAT A . F 6 HOH 776 2780 776 HOH WAT A . F 6 HOH 777 2781 777 HOH WAT A . F 6 HOH 778 2782 778 HOH WAT A . F 6 HOH 779 2783 779 HOH WAT A . F 6 HOH 780 2784 780 HOH WAT A . F 6 HOH 781 2785 781 HOH WAT A . F 6 HOH 782 2786 782 HOH WAT A . F 6 HOH 783 2787 783 HOH WAT A . F 6 HOH 784 2788 784 HOH WAT A . F 6 HOH 785 2789 785 HOH WAT A . F 6 HOH 786 2790 786 HOH WAT A . F 6 HOH 787 2791 787 HOH WAT A . F 6 HOH 788 2792 788 HOH WAT A . F 6 HOH 789 2793 789 HOH WAT A . F 6 HOH 790 2794 790 HOH WAT A . F 6 HOH 791 2795 791 HOH WAT A . F 6 HOH 792 2796 792 HOH WAT A . F 6 HOH 793 2797 793 HOH WAT A . F 6 HOH 794 2798 794 HOH WAT A . F 6 HOH 795 2799 795 HOH WAT A . F 6 HOH 796 2800 796 HOH WAT A . F 6 HOH 797 2801 797 HOH WAT A . F 6 HOH 798 2802 798 HOH WAT A . F 6 HOH 799 2803 799 HOH WAT A . F 6 HOH 800 2804 800 HOH WAT A . F 6 HOH 801 2805 801 HOH WAT A . F 6 HOH 802 2806 802 HOH WAT A . F 6 HOH 803 2807 803 HOH WAT A . F 6 HOH 804 2808 804 HOH WAT A . F 6 HOH 805 2809 805 HOH WAT A . F 6 HOH 806 2810 806 HOH WAT A . F 6 HOH 807 2811 807 HOH WAT A . F 6 HOH 808 2812 808 HOH WAT A . F 6 HOH 809 2813 809 HOH WAT A . F 6 HOH 810 2814 810 HOH WAT A . F 6 HOH 811 2815 811 HOH WAT A . F 6 HOH 812 2816 812 HOH WAT A . F 6 HOH 813 2817 813 HOH WAT A . F 6 HOH 814 2818 814 HOH WAT A . F 6 HOH 815 2819 815 HOH WAT A . F 6 HOH 816 2820 816 HOH WAT A . F 6 HOH 817 2821 817 HOH WAT A . F 6 HOH 818 2822 818 HOH WAT A . F 6 HOH 819 2823 819 HOH WAT A . F 6 HOH 820 2824 820 HOH WAT A . F 6 HOH 821 2825 821 HOH WAT A . F 6 HOH 822 2826 822 HOH WAT A . F 6 HOH 823 2827 823 HOH WAT A . F 6 HOH 824 2828 824 HOH WAT A . F 6 HOH 825 2829 825 HOH WAT A . F 6 HOH 826 2830 826 HOH WAT A . F 6 HOH 827 2831 827 HOH WAT A . F 6 HOH 828 2832 828 HOH WAT A . F 6 HOH 829 2833 829 HOH WAT A . F 6 HOH 830 2834 830 HOH WAT A . F 6 HOH 831 2835 831 HOH WAT A . F 6 HOH 832 2836 832 HOH WAT A . F 6 HOH 833 2837 833 HOH WAT A . F 6 HOH 834 2838 834 HOH WAT A . F 6 HOH 835 2839 835 HOH WAT A . F 6 HOH 836 2840 836 HOH WAT A . F 6 HOH 837 2841 837 HOH WAT A . F 6 HOH 838 2842 838 HOH WAT A . F 6 HOH 839 2843 839 HOH WAT A . F 6 HOH 840 2844 840 HOH WAT A . F 6 HOH 841 2845 841 HOH WAT A . F 6 HOH 842 2846 842 HOH WAT A . F 6 HOH 843 2847 843 HOH WAT A . F 6 HOH 844 2848 844 HOH WAT A . F 6 HOH 845 2849 845 HOH WAT A . F 6 HOH 846 2850 846 HOH WAT A . F 6 HOH 847 2851 847 HOH WAT A . F 6 HOH 848 2852 848 HOH WAT A . F 6 HOH 849 2853 849 HOH WAT A . F 6 HOH 850 2854 850 HOH WAT A . F 6 HOH 851 2855 851 HOH WAT A . F 6 HOH 852 2856 852 HOH WAT A . F 6 HOH 853 2857 853 HOH WAT A . F 6 HOH 854 2858 854 HOH WAT A . F 6 HOH 855 2859 855 HOH WAT A . F 6 HOH 856 2860 856 HOH WAT A . F 6 HOH 857 2861 857 HOH WAT A . F 6 HOH 858 2862 858 HOH WAT A . F 6 HOH 859 2863 859 HOH WAT A . F 6 HOH 860 2864 860 HOH WAT A . F 6 HOH 861 2865 861 HOH WAT A . F 6 HOH 862 2866 862 HOH WAT A . F 6 HOH 863 2867 863 HOH WAT A . F 6 HOH 864 2868 864 HOH WAT A . F 6 HOH 865 2869 865 HOH WAT A . F 6 HOH 866 2870 866 HOH WAT A . F 6 HOH 867 2871 867 HOH WAT A . F 6 HOH 868 2872 868 HOH WAT A . F 6 HOH 869 2873 869 HOH WAT A . F 6 HOH 870 2874 870 HOH WAT A . F 6 HOH 871 2875 871 HOH WAT A . F 6 HOH 872 2876 872 HOH WAT A . F 6 HOH 873 2877 873 HOH WAT A . F 6 HOH 874 2878 874 HOH WAT A . F 6 HOH 875 2879 875 HOH WAT A . F 6 HOH 876 2880 876 HOH WAT A . F 6 HOH 877 2881 877 HOH WAT A . F 6 HOH 878 2882 878 HOH WAT A . F 6 HOH 879 2883 879 HOH WAT A . F 6 HOH 880 2884 880 HOH WAT A . F 6 HOH 881 2885 881 HOH WAT A . F 6 HOH 882 2886 882 HOH WAT A . F 6 HOH 883 2887 883 HOH WAT A . F 6 HOH 884 2888 884 HOH WAT A . F 6 HOH 885 2889 885 HOH WAT A . F 6 HOH 886 2890 886 HOH WAT A . F 6 HOH 887 2891 887 HOH WAT A . F 6 HOH 888 2892 888 HOH WAT A . F 6 HOH 889 2893 889 HOH WAT A . F 6 HOH 890 2894 890 HOH WAT A . F 6 HOH 891 2895 891 HOH WAT A . F 6 HOH 892 2896 892 HOH WAT A . F 6 HOH 893 2897 893 HOH WAT A . F 6 HOH 894 2898 894 HOH WAT A . F 6 HOH 895 2899 895 HOH WAT A . F 6 HOH 896 2900 896 HOH WAT A . F 6 HOH 897 2901 897 HOH WAT A . F 6 HOH 898 2902 898 HOH WAT A . F 6 HOH 899 2903 899 HOH WAT A . F 6 HOH 900 2904 900 HOH WAT A . F 6 HOH 901 2905 901 HOH WAT A . F 6 HOH 902 2906 902 HOH WAT A . F 6 HOH 903 2907 903 HOH WAT A . F 6 HOH 904 2908 904 HOH WAT A . F 6 HOH 905 2909 905 HOH WAT A . F 6 HOH 906 2910 906 HOH WAT A . F 6 HOH 907 2911 907 HOH WAT A . F 6 HOH 908 2912 908 HOH WAT A . F 6 HOH 909 2913 909 HOH WAT A . F 6 HOH 910 2914 910 HOH WAT A . F 6 HOH 911 2915 911 HOH WAT A . F 6 HOH 912 2916 912 HOH WAT A . F 6 HOH 913 2917 913 HOH WAT A . F 6 HOH 914 2918 914 HOH WAT A . F 6 HOH 915 2919 915 HOH WAT A . F 6 HOH 916 2920 916 HOH WAT A . F 6 HOH 917 2921 917 HOH WAT A . F 6 HOH 918 2922 918 HOH WAT A . F 6 HOH 919 2923 919 HOH WAT A . F 6 HOH 920 2924 920 HOH WAT A . F 6 HOH 921 2925 921 HOH WAT A . F 6 HOH 922 2926 922 HOH WAT A . F 6 HOH 923 2927 923 HOH WAT A . F 6 HOH 924 2928 924 HOH WAT A . F 6 HOH 925 2929 925 HOH WAT A . F 6 HOH 926 2930 926 HOH WAT A . F 6 HOH 927 2931 927 HOH WAT A . F 6 HOH 928 2932 928 HOH WAT A . F 6 HOH 929 2933 929 HOH WAT A . F 6 HOH 930 2934 930 HOH WAT A . F 6 HOH 931 2935 931 HOH WAT A . F 6 HOH 932 2936 932 HOH WAT A . F 6 HOH 933 2937 933 HOH WAT A . F 6 HOH 934 2938 934 HOH WAT A . F 6 HOH 935 2939 935 HOH WAT A . F 6 HOH 936 2940 936 HOH WAT A . F 6 HOH 937 2941 937 HOH WAT A . F 6 HOH 938 2942 938 HOH WAT A . F 6 HOH 939 2943 939 HOH WAT A . F 6 HOH 940 2944 940 HOH WAT A . F 6 HOH 941 2945 941 HOH WAT A . F 6 HOH 942 2946 942 HOH WAT A . F 6 HOH 943 2947 943 HOH WAT A . F 6 HOH 944 2948 944 HOH WAT A . F 6 HOH 945 2949 945 HOH WAT A . F 6 HOH 946 2950 946 HOH WAT A . F 6 HOH 947 2951 947 HOH WAT A . F 6 HOH 948 2952 948 HOH WAT A . F 6 HOH 949 2953 949 HOH WAT A . F 6 HOH 950 2954 950 HOH WAT A . F 6 HOH 951 2955 951 HOH WAT A . F 6 HOH 952 2956 952 HOH WAT A . F 6 HOH 953 2957 953 HOH WAT A . F 6 HOH 954 2958 954 HOH WAT A . F 6 HOH 955 2959 955 HOH WAT A . F 6 HOH 956 2960 956 HOH WAT A . F 6 HOH 957 2961 957 HOH WAT A . F 6 HOH 958 2962 958 HOH WAT A . F 6 HOH 959 2963 959 HOH WAT A . F 6 HOH 960 2964 960 HOH WAT A . F 6 HOH 961 2965 961 HOH WAT A . F 6 HOH 962 2966 962 HOH WAT A . F 6 HOH 963 2967 963 HOH WAT A . F 6 HOH 964 2968 964 HOH WAT A . F 6 HOH 965 2969 965 HOH WAT A . F 6 HOH 966 2970 966 HOH WAT A . F 6 HOH 967 2971 967 HOH WAT A . F 6 HOH 968 2972 968 HOH WAT A . F 6 HOH 969 2973 969 HOH WAT A . F 6 HOH 970 2974 970 HOH WAT A . F 6 HOH 971 2975 971 HOH WAT A . F 6 HOH 972 2976 972 HOH WAT A . F 6 HOH 973 2977 973 HOH WAT A . F 6 HOH 974 2978 974 HOH WAT A . F 6 HOH 975 2979 975 HOH WAT A . F 6 HOH 976 2980 976 HOH WAT A . F 6 HOH 977 2981 977 HOH WAT A . F 6 HOH 978 2982 978 HOH WAT A . F 6 HOH 979 2983 979 HOH WAT A . F 6 HOH 980 2984 980 HOH WAT A . F 6 HOH 981 2985 981 HOH WAT A . F 6 HOH 982 2986 982 HOH WAT A . F 6 HOH 983 2987 983 HOH WAT A . F 6 HOH 984 2988 984 HOH WAT A . F 6 HOH 985 2989 985 HOH WAT A . F 6 HOH 986 2990 986 HOH WAT A . F 6 HOH 987 2991 987 HOH WAT A . F 6 HOH 988 2992 988 HOH WAT A . F 6 HOH 989 2993 989 HOH WAT A . F 6 HOH 990 2994 990 HOH WAT A . F 6 HOH 991 2995 991 HOH WAT A . F 6 HOH 992 2996 992 HOH WAT A . F 6 HOH 993 2997 993 HOH WAT A . F 6 HOH 994 2998 994 HOH WAT A . F 6 HOH 995 2999 995 HOH WAT A . F 6 HOH 996 3000 996 HOH WAT A . F 6 HOH 997 3001 997 HOH WAT A . F 6 HOH 998 3002 998 HOH WAT A . F 6 HOH 999 3003 999 HOH WAT A . F 6 HOH 1000 3004 1000 HOH WAT A . F 6 HOH 1001 3005 1001 HOH WAT A . F 6 HOH 1002 3006 1002 HOH WAT A . F 6 HOH 1003 3007 1003 HOH WAT A . F 6 HOH 1004 3008 1004 HOH WAT A . F 6 HOH 1005 3009 1005 HOH WAT A . F 6 HOH 1006 3010 1006 HOH WAT A . F 6 HOH 1007 3011 1007 HOH WAT A . F 6 HOH 1008 3012 1008 HOH WAT A . F 6 HOH 1009 3013 1009 HOH WAT A . F 6 HOH 1010 3014 1010 HOH WAT A . F 6 HOH 1011 3015 1011 HOH WAT A . F 6 HOH 1012 3016 1012 HOH WAT A . F 6 HOH 1013 3017 1013 HOH WAT A . F 6 HOH 1014 3018 1014 HOH WAT A . F 6 HOH 1015 3019 1015 HOH WAT A . F 6 HOH 1016 3020 1016 HOH WAT A . F 6 HOH 1017 3021 1017 HOH WAT A . F 6 HOH 1018 3022 1018 HOH WAT A . F 6 HOH 1019 3023 1019 HOH WAT A . F 6 HOH 1020 3024 1020 HOH WAT A . F 6 HOH 1021 3025 1021 HOH WAT A . F 6 HOH 1022 3026 1022 HOH WAT A . F 6 HOH 1023 3027 1023 HOH WAT A . F 6 HOH 1024 3028 1024 HOH WAT A . F 6 HOH 1025 3029 1025 HOH WAT A . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 194 _pdbx_struct_mod_residue.auth_asym_id A _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 194 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O2 ? D GUL . ? A GUL 2003 ? 1_555 91.0 ? 2 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 98.4 ? 3 O2 ? D GUL . ? A GUL 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 92.4 ? 4 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 98.3 ? 5 O2 ? D GUL . ? A GUL 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 163.4 ? 6 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 99.7 ? 7 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O3 ? D GUL . ? A GUL 2003 ? 1_555 164.8 ? 8 O2 ? D GUL . ? A GUL 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O3 ? D GUL . ? A GUL 2003 ? 1_555 75.0 ? 9 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O3 ? D GUL . ? A GUL 2003 ? 1_555 88.4 ? 10 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 O3 ? D GUL . ? A GUL 2003 ? 1_555 93.9 ? 11 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 89.8 ? 12 O2 ? D GUL . ? A GUL 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 70.0 ? 13 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 160.8 ? 14 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 96.2 ? 15 O3 ? D GUL . ? A GUL 2003 ? 1_555 ZN ? C ZN . ? A ZN 2004 ? 1_555 OD1 ? A ASP 204 ? A ASP 204 ? 1_555 79.8 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2003-10-07 2 'Structure model' 1 1 2008-04-29 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal CNS refinement 1.0 ? 1 DENZO 'data reduction' . ? 2 SCALEPACK 'data scaling' . ? 3 CNS phasing . ? 4 # _pdbx_database_remark.id 999 _pdbx_database_remark.text ;SEQUENCE The E -> K conflict for residue 970 is noted in Swiss-Prot entry Q24451. ; # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OH A TYR 75 ? ? O A HOH 3014 ? ? 2.08 2 1 O A HOH 2861 ? ? O A HOH 2864 ? ? 2.15 3 1 O A HOH 2338 ? ? O A HOH 2589 ? ? 2.19 # _pdbx_validate_symm_contact.id 1 _pdbx_validate_symm_contact.PDB_model_num 1 _pdbx_validate_symm_contact.auth_atom_id_1 O _pdbx_validate_symm_contact.auth_asym_id_1 A _pdbx_validate_symm_contact.auth_comp_id_1 HOH _pdbx_validate_symm_contact.auth_seq_id_1 2682 _pdbx_validate_symm_contact.PDB_ins_code_1 ? _pdbx_validate_symm_contact.label_alt_id_1 ? _pdbx_validate_symm_contact.site_symmetry_1 1_555 _pdbx_validate_symm_contact.auth_atom_id_2 O _pdbx_validate_symm_contact.auth_asym_id_2 A _pdbx_validate_symm_contact.auth_comp_id_2 HOH _pdbx_validate_symm_contact.auth_seq_id_2 3021 _pdbx_validate_symm_contact.PDB_ins_code_2 ? _pdbx_validate_symm_contact.label_alt_id_2 ? _pdbx_validate_symm_contact.site_symmetry_2 2_565 _pdbx_validate_symm_contact.dist 2.10 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 HIS A 79 ? ? -154.15 88.41 2 1 TRP A 95 ? ? -170.64 -83.04 3 1 ASP A 106 ? ? -134.59 -58.87 4 1 THR A 162 ? ? 67.17 -62.44 5 1 GLN A 227 ? ? -133.67 -51.78 6 1 PHE A 287 ? ? -69.01 0.89 7 1 SER A 411 ? ? 35.25 -118.63 8 1 ILE A 549 ? ? -143.32 -49.54 9 1 PRO A 562 ? ? -82.45 44.36 10 1 SER A 703 ? ? -41.09 160.18 11 1 ASN A 732 ? ? -93.53 59.15 12 1 SER A 762 ? ? 78.25 -8.40 13 1 SER A 833 ? ? -154.29 -11.12 14 1 ASP A 839 ? ? -129.05 -159.76 15 1 SER A 855 ? ? -170.82 -174.55 16 1 GLU A 991 ? ? 36.42 97.55 17 1 GLU A 992 ? ? -118.09 -151.11 18 1 HIS A 993 ? ? 21.57 85.11 # loop_ _pdbx_validate_planes.id _pdbx_validate_planes.PDB_model_num _pdbx_validate_planes.auth_comp_id _pdbx_validate_planes.auth_asym_id _pdbx_validate_planes.auth_seq_id _pdbx_validate_planes.PDB_ins_code _pdbx_validate_planes.label_alt_id _pdbx_validate_planes.rmsd _pdbx_validate_planes.type 1 1 TYR A 407 ? ? 0.071 'SIDE CHAIN' 2 1 TYR A 646 ? ? 0.069 'SIDE CHAIN' # loop_ _pdbx_validate_chiral.id _pdbx_validate_chiral.PDB_model_num _pdbx_validate_chiral.auth_atom_id _pdbx_validate_chiral.label_alt_id _pdbx_validate_chiral.auth_asym_id _pdbx_validate_chiral.auth_comp_id _pdbx_validate_chiral.auth_seq_id _pdbx_validate_chiral.PDB_ins_code _pdbx_validate_chiral.details _pdbx_validate_chiral.omega 1 1 C1 ? A NAG 2001 ? 'WRONG HAND' . 2 1 C4 ? A MPD 2002 ? 'WRONG HAND' . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ARG 1 ? A ARG 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A SER 3 ? A SER 3 4 1 Y 1 A HIS 4 ? A HIS 4 5 1 Y 1 A HIS 5 ? A HIS 5 6 1 Y 1 A HIS 6 ? A HIS 6 7 1 Y 1 A HIS 7 ? A HIS 7 8 1 Y 1 A HIS 8 ? A HIS 8 9 1 Y 1 A HIS 9 ? A HIS 9 10 1 Y 1 A GLY 10 ? A GLY 10 11 1 Y 1 A GLU 11 ? A GLU 11 12 1 Y 1 A PHE 12 ? A PHE 12 13 1 Y 1 A ASP 13 ? A ASP 13 14 1 Y 1 A ASP 14 ? A ASP 14 15 1 Y 1 A PRO 15 ? A PRO 15 16 1 Y 1 A ILE 16 ? A ILE 16 17 1 Y 1 A ARG 17 ? A ARG 17 18 1 Y 1 A PRO 18 ? A PRO 18 19 1 Y 1 A PRO 19 ? A PRO 19 20 1 Y 1 A LEU 20 ? A LEU 20 21 1 Y 1 A LYS 21 ? A LYS 21 22 1 Y 1 A VAL 22 ? A VAL 22 23 1 Y 1 A ALA 23 ? A ALA 23 24 1 Y 1 A ARG 24 ? A ARG 24 25 1 Y 1 A SER 25 ? A SER 25 26 1 Y 1 A PRO 26 ? A PRO 26 27 1 Y 1 A ARG 27 ? A ARG 27 28 1 Y 1 A PRO 28 ? A PRO 28 29 1 Y 1 A GLY 29 ? A GLY 29 30 1 Y 1 A GLN 30 ? A GLN 30 31 1 Y 1 A SER 1045 ? A SER 1045 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'ZINC ION' ZN 4 '5-FLUORO-BETA-L-GULOSYL FLUORIDE' GUL 5 '(4S)-2-METHYL-2,4-PENTANEDIOL' MPD 6 water HOH #