data_1NCB # _entry.id 1NCB # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 1NCB WWPDB D_1000175225 # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 1NCB _pdbx_database_status.recvd_initial_deposition_date 1992-01-21 _pdbx_database_status.deposit_site ? _pdbx_database_status.process_site ? _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Tulip, W.R.' 1 'Varghese, J.N.' 2 'Colman, P.M.' 3 # loop_ _citation.id _citation.title _citation.journal_abbrev _citation.journal_volume _citation.page_first _citation.page_last _citation.year _citation.journal_id_ASTM _citation.country _citation.journal_id_ISSN _citation.journal_id_CSD _citation.book_publisher _citation.pdbx_database_id_PubMed _citation.pdbx_database_id_DOI primary 'Crystal structures of two mutant neuraminidase-antibody complexes with amino acid substitutions in the interface.' J.Mol.Biol. 227 149 159 1992 JMOBAK UK 0022-2836 0070 ? 1522584 '10.1016/0022-2836(92)90688-G' 1 'Refined Crystal Structure of the Influenza Virus N9 Neuraminidase-Nc41 Fab Complex' J.Mol.Biol. 227 122 ? 1992 JMOBAK UK 0022-2836 0070 ? ? ? 2 'Crystal Structures of Neuraminidase-Antibody Complexes' 'Cold Spring Harbor Symp.Quant.Biol.' 54 257 ? 1989 CSHSAZ US 0091-7451 0421 ? ? ? 3 'Three-Dimensional Structure of a Complex of Antibody with Influenza Virus Neuraminidase' Nature 326 358 ? 1987 NATUAS UK 0028-0836 0006 ? ? ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Tulip, W.R.' 1 primary 'Varghese, J.N.' 2 primary 'Webster, R.G.' 3 primary 'Laver, W.G.' 4 primary 'Colman, P.M.' 5 1 'Tulip, W.R.' 6 1 'Varghese, J.N.' 7 1 'Laver, W.G.' 8 1 'Webster, R.G.' 9 1 'Colman, P.M.' 10 2 'Tulip, W.R.' 11 2 'Varghese, J.N.' 12 2 'Webster, R.G.' 13 2 'Air, G.M.' 14 2 'Laver, W.G.' 15 2 'Colman, P.M.' 16 3 'Colman, P.M.' 17 3 'Laver, W.G.' 18 3 'Varghese, J.N.' 19 3 'Baker, A.T.' 20 3 'Tulloch, P.A.' 21 3 'Air, G.M.' 22 3 'Webster, R.G.' 23 # _cell.entry_id 1NCB _cell.length_a 167.000 _cell.length_b 167.000 _cell.length_c 124.000 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? # _symmetry.entry_id 1NCB _symmetry.space_group_name_H-M 'P 4 21 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 90 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat 'INFLUENZA A SUBTYPE N9 NEURAMINIDASE' 43837.910 1 3.2.1.18 ? ? ? 2 polymer nat 'IGG2A-KAPPA NC41 FAB (LIGHT CHAIN)' 23722.311 1 ? ? ? ? 3 polymer nat 'IGG2A-KAPPA NC41 FAB (HEAVY CHAIN)' 23668.354 1 ? ? ? ? 4 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 5 ? ? ? ? 5 non-polymer man BETA-D-MANNOSE 180.156 1 ? ? ? ? 6 non-polymer man ALPHA-D-MANNOSE 180.156 3 ? ? ? ? 7 non-polymer syn 'CALCIUM ION' 40.078 1 ? ? ? ? 8 water nat water 18.015 72 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;IRDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALIS WPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPV VFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCRDNWQGSNRPVIRIDPVAMTHTSQYICS PVLTDNPRPDDPTVGKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNT DWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL ; ;IRDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALIS WPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPV VFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCRDNWQGSNRPVIRIDPVAMTHTSQYICS PVLTDNPRPDDPTVGKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNT DWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL ; N ? 2 'polypeptide(L)' no no ;DIVMTQSPKFMSTSVGDRVTITCKASQDVSTAVVWYQQKPGQSPKLLIYWASTRHIGVPDRFAGSGSGTDYTLTISSVQA EDLALYYCQQHYSPPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; ;DIVMTQSPKFMSTSVGDRVTITCKASQDVSTAVVWYQQKPGQSPKLLIYWASTRHIGVPDRFAGSGSGTDYTLTISSVQA EDLALYYCQQHYSPPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; L ? 3 'polypeptide(L)' no no ;QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLEWMGWINTNTGEPTYGEEFKGRFAFSLETSASTAN LQINNLKNEDKATFFCARGEDNFGSLSDYWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLT WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRG ; ;QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLEWMGWINTNTGEPTYGEEFKGRFAFSLETSASTAN LQINNLKNEDKATFFCARGEDNFGSLSDYWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLT WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRG ; H ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ILE n 1 2 ARG n 1 3 ASP n 1 4 PHE n 1 5 ASN n 1 6 ASN n 1 7 LEU n 1 8 THR n 1 9 LYS n 1 10 GLY n 1 11 LEU n 1 12 CYS n 1 13 THR n 1 14 ILE n 1 15 ASN n 1 16 SER n 1 17 TRP n 1 18 HIS n 1 19 ILE n 1 20 TYR n 1 21 GLY n 1 22 LYS n 1 23 ASP n 1 24 ASN n 1 25 ALA n 1 26 VAL n 1 27 ARG n 1 28 ILE n 1 29 GLY n 1 30 GLU n 1 31 ASP n 1 32 SER n 1 33 ASP n 1 34 VAL n 1 35 LEU n 1 36 VAL n 1 37 THR n 1 38 ARG n 1 39 GLU n 1 40 PRO n 1 41 TYR n 1 42 VAL n 1 43 SER n 1 44 CYS n 1 45 ASP n 1 46 PRO n 1 47 ASP n 1 48 GLU n 1 49 CYS n 1 50 ARG n 1 51 PHE n 1 52 TYR n 1 53 ALA n 1 54 LEU n 1 55 SER n 1 56 GLN n 1 57 GLY n 1 58 THR n 1 59 THR n 1 60 ILE n 1 61 ARG n 1 62 GLY n 1 63 LYS n 1 64 HIS n 1 65 SER n 1 66 ASN n 1 67 GLY n 1 68 THR n 1 69 ILE n 1 70 HIS n 1 71 ASP n 1 72 ARG n 1 73 SER n 1 74 GLN n 1 75 TYR n 1 76 ARG n 1 77 ALA n 1 78 LEU n 1 79 ILE n 1 80 SER n 1 81 TRP n 1 82 PRO n 1 83 LEU n 1 84 SER n 1 85 SER n 1 86 PRO n 1 87 PRO n 1 88 THR n 1 89 VAL n 1 90 TYR n 1 91 ASN n 1 92 SER n 1 93 ARG n 1 94 VAL n 1 95 GLU n 1 96 CYS n 1 97 ILE n 1 98 GLY n 1 99 TRP n 1 100 SER n 1 101 SER n 1 102 THR n 1 103 SER n 1 104 CYS n 1 105 HIS n 1 106 ASP n 1 107 GLY n 1 108 LYS n 1 109 THR n 1 110 ARG n 1 111 MET n 1 112 SER n 1 113 ILE n 1 114 CYS n 1 115 ILE n 1 116 SER n 1 117 GLY n 1 118 PRO n 1 119 ASN n 1 120 ASN n 1 121 ASN n 1 122 ALA n 1 123 SER n 1 124 ALA n 1 125 VAL n 1 126 ILE n 1 127 TRP n 1 128 TYR n 1 129 ASN n 1 130 ARG n 1 131 ARG n 1 132 PRO n 1 133 VAL n 1 134 THR n 1 135 GLU n 1 136 ILE n 1 137 ASN n 1 138 THR n 1 139 TRP n 1 140 ALA n 1 141 ARG n 1 142 ASN n 1 143 ILE n 1 144 LEU n 1 145 ARG n 1 146 THR n 1 147 GLN n 1 148 GLU n 1 149 SER n 1 150 GLU n 1 151 CYS n 1 152 VAL n 1 153 CYS n 1 154 HIS n 1 155 ASN n 1 156 GLY n 1 157 VAL n 1 158 CYS n 1 159 PRO n 1 160 VAL n 1 161 VAL n 1 162 PHE n 1 163 THR n 1 164 ASP n 1 165 GLY n 1 166 SER n 1 167 ALA n 1 168 THR n 1 169 GLY n 1 170 PRO n 1 171 ALA n 1 172 GLU n 1 173 THR n 1 174 ARG n 1 175 ILE n 1 176 TYR n 1 177 TYR n 1 178 PHE n 1 179 LYS n 1 180 GLU n 1 181 GLY n 1 182 LYS n 1 183 ILE n 1 184 LEU n 1 185 LYS n 1 186 TRP n 1 187 GLU n 1 188 PRO n 1 189 LEU n 1 190 ALA n 1 191 GLY n 1 192 THR n 1 193 ALA n 1 194 LYS n 1 195 HIS n 1 196 ILE n 1 197 GLU n 1 198 GLU n 1 199 CYS n 1 200 SER n 1 201 CYS n 1 202 TYR n 1 203 GLY n 1 204 GLU n 1 205 ARG n 1 206 ALA n 1 207 GLU n 1 208 ILE n 1 209 THR n 1 210 CYS n 1 211 THR n 1 212 CYS n 1 213 ARG n 1 214 ASP n 1 215 ASN n 1 216 TRP n 1 217 GLN n 1 218 GLY n 1 219 SER n 1 220 ASN n 1 221 ARG n 1 222 PRO n 1 223 VAL n 1 224 ILE n 1 225 ARG n 1 226 ILE n 1 227 ASP n 1 228 PRO n 1 229 VAL n 1 230 ALA n 1 231 MET n 1 232 THR n 1 233 HIS n 1 234 THR n 1 235 SER n 1 236 GLN n 1 237 TYR n 1 238 ILE n 1 239 CYS n 1 240 SER n 1 241 PRO n 1 242 VAL n 1 243 LEU n 1 244 THR n 1 245 ASP n 1 246 ASN n 1 247 PRO n 1 248 ARG n 1 249 PRO n 1 250 ASP n 1 251 ASP n 1 252 PRO n 1 253 THR n 1 254 VAL n 1 255 GLY n 1 256 LYS n 1 257 CYS n 1 258 ASN n 1 259 ASP n 1 260 PRO n 1 261 TYR n 1 262 PRO n 1 263 GLY n 1 264 ASN n 1 265 ASN n 1 266 ASN n 1 267 ASN n 1 268 GLY n 1 269 VAL n 1 270 LYS n 1 271 GLY n 1 272 PHE n 1 273 SER n 1 274 TYR n 1 275 LEU n 1 276 ASP n 1 277 GLY n 1 278 VAL n 1 279 ASN n 1 280 THR n 1 281 TRP n 1 282 LEU n 1 283 GLY n 1 284 ARG n 1 285 THR n 1 286 ILE n 1 287 SER n 1 288 ILE n 1 289 ALA n 1 290 SER n 1 291 ARG n 1 292 SER n 1 293 GLY n 1 294 TYR n 1 295 GLU n 1 296 MET n 1 297 LEU n 1 298 LYS n 1 299 VAL n 1 300 PRO n 1 301 ASN n 1 302 ALA n 1 303 LEU n 1 304 THR n 1 305 ASP n 1 306 ASP n 1 307 LYS n 1 308 SER n 1 309 LYS n 1 310 PRO n 1 311 THR n 1 312 GLN n 1 313 GLY n 1 314 GLN n 1 315 THR n 1 316 ILE n 1 317 VAL n 1 318 LEU n 1 319 ASN n 1 320 THR n 1 321 ASP n 1 322 TRP n 1 323 SER n 1 324 GLY n 1 325 TYR n 1 326 SER n 1 327 GLY n 1 328 SER n 1 329 PHE n 1 330 MET n 1 331 ASP n 1 332 TYR n 1 333 TRP n 1 334 ALA n 1 335 GLU n 1 336 GLY n 1 337 GLU n 1 338 CYS n 1 339 TYR n 1 340 ARG n 1 341 ALA n 1 342 CYS n 1 343 PHE n 1 344 TYR n 1 345 VAL n 1 346 GLU n 1 347 LEU n 1 348 ILE n 1 349 ARG n 1 350 GLY n 1 351 ARG n 1 352 PRO n 1 353 LYS n 1 354 GLU n 1 355 ASP n 1 356 LYS n 1 357 VAL n 1 358 TRP n 1 359 TRP n 1 360 THR n 1 361 SER n 1 362 ASN n 1 363 SER n 1 364 ILE n 1 365 VAL n 1 366 SER n 1 367 MET n 1 368 CYS n 1 369 SER n 1 370 SER n 1 371 THR n 1 372 GLU n 1 373 PHE n 1 374 LEU n 1 375 GLY n 1 376 GLN n 1 377 TRP n 1 378 ASP n 1 379 TRP n 1 380 PRO n 1 381 ASP n 1 382 GLY n 1 383 ALA n 1 384 LYS n 1 385 ILE n 1 386 GLU n 1 387 TYR n 1 388 PHE n 1 389 LEU n 2 1 ASP n 2 2 ILE n 2 3 VAL n 2 4 MET n 2 5 THR n 2 6 GLN n 2 7 SER n 2 8 PRO n 2 9 LYS n 2 10 PHE n 2 11 MET n 2 12 SER n 2 13 THR n 2 14 SER n 2 15 VAL n 2 16 GLY n 2 17 ASP n 2 18 ARG n 2 19 VAL n 2 20 THR n 2 21 ILE n 2 22 THR n 2 23 CYS n 2 24 LYS n 2 25 ALA n 2 26 SER n 2 27 GLN n 2 28 ASP n 2 29 VAL n 2 30 SER n 2 31 THR n 2 32 ALA n 2 33 VAL n 2 34 VAL n 2 35 TRP n 2 36 TYR n 2 37 GLN n 2 38 GLN n 2 39 LYS n 2 40 PRO n 2 41 GLY n 2 42 GLN n 2 43 SER n 2 44 PRO n 2 45 LYS n 2 46 LEU n 2 47 LEU n 2 48 ILE n 2 49 TYR n 2 50 TRP n 2 51 ALA n 2 52 SER n 2 53 THR n 2 54 ARG n 2 55 HIS n 2 56 ILE n 2 57 GLY n 2 58 VAL n 2 59 PRO n 2 60 ASP n 2 61 ARG n 2 62 PHE n 2 63 ALA n 2 64 GLY n 2 65 SER n 2 66 GLY n 2 67 SER n 2 68 GLY n 2 69 THR n 2 70 ASP n 2 71 TYR n 2 72 THR n 2 73 LEU n 2 74 THR n 2 75 ILE n 2 76 SER n 2 77 SER n 2 78 VAL n 2 79 GLN n 2 80 ALA n 2 81 GLU n 2 82 ASP n 2 83 LEU n 2 84 ALA n 2 85 LEU n 2 86 TYR n 2 87 TYR n 2 88 CYS n 2 89 GLN n 2 90 GLN n 2 91 HIS n 2 92 TYR n 2 93 SER n 2 94 PRO n 2 95 PRO n 2 96 TRP n 2 97 THR n 2 98 PHE n 2 99 GLY n 2 100 GLY n 2 101 GLY n 2 102 THR n 2 103 LYS n 2 104 LEU n 2 105 GLU n 2 106 ILE n 2 107 LYS n 2 108 ARG n 2 109 ALA n 2 110 ASP n 2 111 ALA n 2 112 ALA n 2 113 PRO n 2 114 THR n 2 115 VAL n 2 116 SER n 2 117 ILE n 2 118 PHE n 2 119 PRO n 2 120 PRO n 2 121 SER n 2 122 SER n 2 123 GLU n 2 124 GLN n 2 125 LEU n 2 126 THR n 2 127 SER n 2 128 GLY n 2 129 GLY n 2 130 ALA n 2 131 SER n 2 132 VAL n 2 133 VAL n 2 134 CYS n 2 135 PHE n 2 136 LEU n 2 137 ASN n 2 138 ASN n 2 139 PHE n 2 140 TYR n 2 141 PRO n 2 142 LYS n 2 143 ASP n 2 144 ILE n 2 145 ASN n 2 146 VAL n 2 147 LYS n 2 148 TRP n 2 149 LYS n 2 150 ILE n 2 151 ASP n 2 152 GLY n 2 153 SER n 2 154 GLU n 2 155 ARG n 2 156 GLN n 2 157 ASN n 2 158 GLY n 2 159 VAL n 2 160 LEU n 2 161 ASN n 2 162 SER n 2 163 TRP n 2 164 THR n 2 165 ASP n 2 166 GLN n 2 167 ASP n 2 168 SER n 2 169 LYS n 2 170 ASP n 2 171 SER n 2 172 THR n 2 173 TYR n 2 174 SER n 2 175 MET n 2 176 SER n 2 177 SER n 2 178 THR n 2 179 LEU n 2 180 THR n 2 181 LEU n 2 182 THR n 2 183 LYS n 2 184 ASP n 2 185 GLU n 2 186 TYR n 2 187 GLU n 2 188 ARG n 2 189 HIS n 2 190 ASN n 2 191 SER n 2 192 TYR n 2 193 THR n 2 194 CYS n 2 195 GLU n 2 196 ALA n 2 197 THR n 2 198 HIS n 2 199 LYS n 2 200 THR n 2 201 SER n 2 202 THR n 2 203 SER n 2 204 PRO n 2 205 ILE n 2 206 VAL n 2 207 LYS n 2 208 SER n 2 209 PHE n 2 210 ASN n 2 211 ARG n 2 212 ASN n 2 213 GLU n 2 214 CYS n 3 1 GLN n 3 2 ILE n 3 3 GLN n 3 4 LEU n 3 5 VAL n 3 6 GLN n 3 7 SER n 3 8 GLY n 3 9 PRO n 3 10 GLU n 3 11 LEU n 3 12 LYS n 3 13 LYS n 3 14 PRO n 3 15 GLY n 3 16 GLU n 3 17 THR n 3 18 VAL n 3 19 LYS n 3 20 ILE n 3 21 SER n 3 22 CYS n 3 23 LYS n 3 24 ALA n 3 25 SER n 3 26 GLY n 3 27 TYR n 3 28 THR n 3 29 PHE n 3 30 THR n 3 31 ASN n 3 32 TYR n 3 33 GLY n 3 34 MET n 3 35 ASN n 3 36 TRP n 3 37 VAL n 3 38 LYS n 3 39 GLN n 3 40 ALA n 3 41 PRO n 3 42 GLY n 3 43 LYS n 3 44 GLY n 3 45 LEU n 3 46 GLU n 3 47 TRP n 3 48 MET n 3 49 GLY n 3 50 TRP n 3 51 ILE n 3 52 ASN n 3 53 THR n 3 54 ASN n 3 55 THR n 3 56 GLY n 3 57 GLU n 3 58 PRO n 3 59 THR n 3 60 TYR n 3 61 GLY n 3 62 GLU n 3 63 GLU n 3 64 PHE n 3 65 LYS n 3 66 GLY n 3 67 ARG n 3 68 PHE n 3 69 ALA n 3 70 PHE n 3 71 SER n 3 72 LEU n 3 73 GLU n 3 74 THR n 3 75 SER n 3 76 ALA n 3 77 SER n 3 78 THR n 3 79 ALA n 3 80 ASN n 3 81 LEU n 3 82 GLN n 3 83 ILE n 3 84 ASN n 3 85 ASN n 3 86 LEU n 3 87 LYS n 3 88 ASN n 3 89 GLU n 3 90 ASP n 3 91 LYS n 3 92 ALA n 3 93 THR n 3 94 PHE n 3 95 PHE n 3 96 CYS n 3 97 ALA n 3 98 ARG n 3 99 GLY n 3 100 GLU n 3 101 ASP n 3 102 ASN n 3 103 PHE n 3 104 GLY n 3 105 SER n 3 106 LEU n 3 107 SER n 3 108 ASP n 3 109 TYR n 3 110 TRP n 3 111 GLY n 3 112 GLN n 3 113 GLY n 3 114 THR n 3 115 THR n 3 116 LEU n 3 117 THR n 3 118 VAL n 3 119 SER n 3 120 SER n 3 121 ALA n 3 122 LYS n 3 123 THR n 3 124 THR n 3 125 ALA n 3 126 PRO n 3 127 SER n 3 128 VAL n 3 129 TYR n 3 130 PRO n 3 131 LEU n 3 132 ALA n 3 133 PRO n 3 134 VAL n 3 135 CYS n 3 136 GLY n 3 137 ASP n 3 138 THR n 3 139 THR n 3 140 GLY n 3 141 SER n 3 142 SER n 3 143 VAL n 3 144 THR n 3 145 LEU n 3 146 GLY n 3 147 CYS n 3 148 LEU n 3 149 VAL n 3 150 LYS n 3 151 GLY n 3 152 TYR n 3 153 PHE n 3 154 PRO n 3 155 GLU n 3 156 PRO n 3 157 VAL n 3 158 THR n 3 159 LEU n 3 160 THR n 3 161 TRP n 3 162 ASN n 3 163 SER n 3 164 GLY n 3 165 SER n 3 166 LEU n 3 167 SER n 3 168 SER n 3 169 GLY n 3 170 VAL n 3 171 HIS n 3 172 THR n 3 173 PHE n 3 174 PRO n 3 175 ALA n 3 176 VAL n 3 177 LEU n 3 178 GLN n 3 179 SER n 3 180 ASP n 3 181 LEU n 3 182 TYR n 3 183 THR n 3 184 LEU n 3 185 SER n 3 186 SER n 3 187 SER n 3 188 VAL n 3 189 THR n 3 190 VAL n 3 191 THR n 3 192 SER n 3 193 SER n 3 194 THR n 3 195 TRP n 3 196 PRO n 3 197 SER n 3 198 GLN n 3 199 SER n 3 200 ILE n 3 201 THR n 3 202 CYS n 3 203 ASN n 3 204 VAL n 3 205 ALA n 3 206 HIS n 3 207 PRO n 3 208 ALA n 3 209 SER n 3 210 SER n 3 211 THR n 3 212 LYS n 3 213 VAL n 3 214 ASP n 3 215 LYS n 3 216 LYS n 3 217 ILE n 3 218 GLU n 3 219 PRO n 3 220 ARG n 3 221 GLY n # loop_ _entity_src_nat.entity_id _entity_src_nat.pdbx_src_id _entity_src_nat.pdbx_alt_source_flag _entity_src_nat.pdbx_beg_seq_num _entity_src_nat.pdbx_end_seq_num _entity_src_nat.common_name _entity_src_nat.pdbx_organism_scientific _entity_src_nat.pdbx_ncbi_taxonomy_id _entity_src_nat.genus _entity_src_nat.species _entity_src_nat.strain _entity_src_nat.tissue _entity_src_nat.tissue_fraction _entity_src_nat.pdbx_secretion _entity_src_nat.pdbx_fragment _entity_src_nat.pdbx_variant _entity_src_nat.pdbx_cell_line _entity_src_nat.pdbx_atcc _entity_src_nat.pdbx_cellular_location _entity_src_nat.pdbx_organ _entity_src_nat.pdbx_organelle _entity_src_nat.pdbx_cell _entity_src_nat.pdbx_plasmid_name _entity_src_nat.pdbx_plasmid_details _entity_src_nat.details 1 1 sample ? ? ? 'Influenza A virus' 384509 'Influenzavirus A' 'Influenza A virus' '(A/tern/Australia/G70C/1975(H11N9))' ? ? ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample ? ? 'house mouse' 'Mus musculus' 10090 Mus ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 3 1 sample ? ? 'house mouse' 'Mus musculus' 10090 Mus ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.entity_id _struct_ref.pdbx_db_accession _struct_ref.pdbx_align_begin _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_db_isoform 1 UNP NRAM_IATRA 1 P03472 1 ;MNPNQKILCTSATALVIGTIAVLIGITNLGLNIGLHLKPSCNCSHSQPEATNASQTIINNYYNDTNITQISNTNIQVEER AIRDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALI SWPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCP VVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCRDNWQGSNRPVIRIDPVAMTHTSQYIC SPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLN TDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL ; ? 2 EMBL CAA72328 2 Y11589 1 ;DIVMTQSPKFMSTSVGDRVSVTCKASQIVGTNVAWYQQKPGQSPKALIYSASYRYSGVPDRFTGSGSGTDFTLTISNVQS EDLAEYFCQQYNRYPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; ? 3 UNP GCAM_MOUSE 3 P01865 1 ;AKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSI TCNVAHPASSTKVDKKIEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISW FVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEE MTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHT TKSFSRTPGLDLDDVCAEAQDGELDGLWTTITIFISLFLLSVCYSASVTLFKVKWIFSSVVELKQTISPDYRNMIGQGA ; ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 1NCB N 1 ? 389 ? P03472 82 ? 470 ? 81 468 2 2 1NCB L 1 ? 214 ? Y11589 1 ? 214 ? 1 214 3 3 1NCB H 121 ? 221 ? P01865 1 ? 101 ? 114 227 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 1NCB ASP N 250 ? UNP P03472 ASN 331 CONFLICT 329 1 2 1NCB THR L 20 ? EMBL Y11589 SER 20 CONFLICT 20 2 2 1NCB ILE L 21 ? EMBL Y11589 VAL 21 CONFLICT 21 3 2 1NCB ASP L 28 ? EMBL Y11589 ILE 28 CONFLICT 28 4 2 1NCB SER L 30 ? EMBL Y11589 GLY 30 CONFLICT 30 5 2 1NCB ALA L 32 ? EMBL Y11589 ASN 32 CONFLICT 32 6 2 1NCB VAL L 34 ? EMBL Y11589 ALA 34 CONFLICT 34 7 2 1NCB LEU L 46 ? EMBL Y11589 ALA 46 CONFLICT 46 8 2 1NCB TRP L 50 ? EMBL Y11589 SER 50 CONFLICT 50 9 2 1NCB THR L 53 ? EMBL Y11589 TYR 53 CONFLICT 53 10 2 1NCB HIS L 55 ? EMBL Y11589 TYR 55 CONFLICT 55 11 2 1NCB ILE L 56 ? EMBL Y11589 SER 56 CONFLICT 56 12 2 1NCB ALA L 63 ? EMBL Y11589 THR 63 CONFLICT 63 13 2 1NCB TYR L 71 ? EMBL Y11589 PHE 71 CONFLICT 71 14 2 1NCB SER L 77 ? EMBL Y11589 ASN 77 CONFLICT 77 15 2 1NCB ALA L 80 ? EMBL Y11589 SER 80 CONFLICT 80 16 2 1NCB LEU L 85 ? EMBL Y11589 GLU 85 CONFLICT 85 17 2 1NCB TYR L 87 ? EMBL Y11589 PHE 87 CONFLICT 87 18 2 1NCB HIS L 91 ? EMBL Y11589 TYR 91 CONFLICT 91 19 2 1NCB TYR L 92 ? EMBL Y11589 ASN 92 CONFLICT 92 20 2 1NCB SER L 93 ? EMBL Y11589 ARG 93 CONFLICT 93 21 2 1NCB PRO L 94 ? EMBL Y11589 TYR 94 CONFLICT 94 22 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CA non-polymer . 'CALCIUM ION' ? 'Ca 2' 40.078 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 1NCB _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number ? # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 4.74 _exptl_crystal.density_percent_sol 74.03 _exptl_crystal.description ? # _diffrn.id 1 _diffrn.ambient_temp ? _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l ? _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength . _diffrn_radiation_wavelength.wt 1.0 # _refine.entry_id 1NCB _refine.ls_number_reflns_obs 19343 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 8.0 _refine.ls_d_res_high 2.5 _refine.ls_percent_reflns_obs ? _refine.ls_R_factor_obs 0.165 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.165 _refine.ls_R_factor_R_free ? _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free ? _refine.ls_number_reflns_R_free ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.B_iso_mean ? _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details ? _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_ls_cross_valid_method ? _refine.details ;THE COORDINATES OF THE CALCIUM ATOM ARE NOT WELL DETERMINED. THE REFERENCE STRUCTURE FOR THE CALCIUM ATOM IS THE N9 MUTANT S370L (PDB ENTRY 2NN9). ; _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_overall_phase_error ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6407 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 115 _refine_hist.number_atoms_solvent 72 _refine_hist.number_atoms_total 6594 _refine_hist.d_res_high 2.5 _refine_hist.d_res_low 8.0 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function x_bond_d 0.016 ? ? ? 'X-RAY DIFFRACTION' ? x_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_deg 3.6 ? ? ? 'X-RAY DIFFRACTION' ? x_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_dihedral_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? x_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_improper_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? x_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_mcbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? x_mcangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? x_scbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? x_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? # _struct.entry_id 1NCB _struct.title 'CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE' _struct.pdbx_descriptor 'N9 NEURAMINIDASE-NC41 (E.C.3.2.1.18) MUTANT WITH ASN 329 REPLACED BY ASP (N329D) COMPLEX WITH FAB' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 1NCB _struct_keywords.pdbx_keywords 'HYDROLASE(O-GLYCOSYL)' _struct_keywords.text 'HYDROLASE(O-GLYCOSYL)' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 4 ? F N N 5 ? G N N 6 ? H N N 6 ? I N N 6 ? J N N 4 ? K N N 4 ? L N N 4 ? M N N 7 ? N N N 8 ? O N N 8 ? P N N 8 ? # _struct_biol.id 1 _struct_biol.details ;THE COORDINATES OF THE CARBOHYDRATE IN THE EPITOPE CAN BE GENERATED FORM THE COORDINATES OF RESIDUES C 200A-C 200F BY APPLYING THE FOLLOWING TRANSFORMATION: 0.0 1.0 0.0 83.5 -1.0 0.0 0.0 83.5 0.0 0.0 1.0 0.0 ; _struct_biol.pdbx_parent_biol_id ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 H1 ASN A 24 ? ASP A 31 ? ASN N 104 ASP N 111 1 ? 8 HELX_P HELX_P2 H2 GLY A 62 ? ASN A 66 ? GLY N 142 ASN N 146 1 ? 5 HELX_P HELX_P3 H3 ASN A 301 ? ASP A 305 ? ASN N 381 ASP N 385 1 ? 5 HELX_P HELX_P4 H4 LYS A 384 ? LEU A 389 ? LYS N 463 LEU N 468 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 12 SG ? ? ? 1_555 A CYS 338 SG ? ? N CYS 92 N CYS 417 1_555 ? ? ? ? ? ? ? 2.034 ? disulf2 disulf ? ? A CYS 44 SG ? ? ? 1_555 A CYS 49 SG ? ? N CYS 124 N CYS 129 1_555 ? ? ? ? ? ? ? 1.994 ? disulf3 disulf ? ? A CYS 96 SG ? ? ? 1_555 A CYS 114 SG ? ? N CYS 175 N CYS 193 1_555 ? ? ? ? ? ? ? 2.011 ? disulf4 disulf ? ? A CYS 104 SG ? ? ? 1_555 A CYS 151 SG ? ? N CYS 183 N CYS 230 1_555 ? ? ? ? ? ? ? 2.003 ? disulf5 disulf ? ? A CYS 153 SG ? ? ? 1_555 A CYS 158 SG ? ? N CYS 232 N CYS 237 1_555 ? ? ? ? ? ? ? 1.996 ? disulf6 disulf ? ? A CYS 199 SG ? ? ? 1_555 A CYS 212 SG ? ? N CYS 278 N CYS 291 1_555 ? ? ? ? ? ? ? 2.019 ? disulf7 disulf ? ? A CYS 201 SG ? ? ? 1_555 A CYS 210 SG ? ? N CYS 280 N CYS 289 1_555 ? ? ? ? ? ? ? 2.025 ? disulf8 disulf ? ? A CYS 239 SG ? ? ? 1_555 A CYS 257 SG ? ? N CYS 318 N CYS 337 1_555 ? ? ? ? ? ? ? 1.998 ? disulf9 disulf ? ? A CYS 342 SG ? ? ? 1_555 A CYS 368 SG ? ? N CYS 421 N CYS 447 1_555 ? ? ? ? ? ? ? 2.010 ? disulf10 disulf ? ? B CYS 23 SG ? ? ? 1_555 B CYS 88 SG ? ? L CYS 23 L CYS 88 1_555 ? ? ? ? ? ? ? 2.014 ? disulf11 disulf ? ? B CYS 134 SG ? ? ? 1_555 B CYS 194 SG ? ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.026 ? disulf12 disulf ? ? B CYS 214 SG ? ? ? 1_555 C CYS 135 SG ? ? L CYS 214 H CYS 128 1_555 ? ? ? ? ? ? ? 2.019 ? disulf13 disulf ? ? C CYS 22 SG ? ? ? 1_555 C CYS 96 SG ? ? H CYS 22 H CYS 92 1_555 ? ? ? ? ? ? ? 2.010 ? disulf14 disulf ? ? C CYS 147 SG ? ? ? 1_555 C CYS 202 SG ? ? H CYS 142 H CYS 208 1_555 ? ? ? ? ? ? ? 2.004 ? covale1 covale ? ? A ASN 6 ND2 ? ? ? 1_555 J NAG . C1 ? A N ASN 86 N NAG 475 1_555 ? ? ? ? ? ? ? 1.434 ? covale2 covale ? ? A ASN 66 ND2 ? ? ? 1_555 K NAG . C1 ? A N ASN 146 N NAG 476 1_555 ? ? ? ? ? ? ? 1.442 ? covale3 covale ? ? A ASN 121 ND2 ? ? ? 1_555 D NAG . C1 ? A N ASN 200 N NAG 469 1_555 ? ? ? ? ? ? ? 1.479 ? covale4 covale ? ? D NAG . O4 ? A ? 1_555 E NAG . C1 ? B N NAG 469 N NAG 470 1_555 ? ? ? ? ? ? ? 1.445 ? covale5 covale ? ? E NAG . O4 ? B ? 1_555 F BMA . C1 ? C N NAG 470 N BMA 471 1_555 ? ? ? ? ? ? ? 1.427 ? covale6 covale ? ? F BMA . O3 ? C ? 1_555 G MAN . C1 ? D N BMA 471 N MAN 472 1_555 ? ? ? ? ? ? ? 1.403 ? covale7 covale ? ? G MAN . O2 ? D ? 1_555 H MAN . C1 ? E N MAN 472 N MAN 473 1_555 ? ? ? ? ? ? ? 1.434 ? covale8 covale ? ? H MAN . O2 ? E ? 1_555 I MAN . C1 ? F N MAN 473 N MAN 474 1_555 ? ? ? ? ? ? ? 1.424 ? covale9 covale ? ? K NAG . O4 ? A ? 1_555 L NAG . C1 ? B N NAG 476 N NAG 477 1_555 ? ? ? ? ? ? ? 1.448 ? metalc1 metalc ? ? M CA . CA ? ? ? 1_555 A ASN 267 O ? ? N CA 0 N ASN 347 1_555 ? ? ? ? ? ? ? 1.745 ? metalc2 metalc ? ? M CA . CA ? ? ? 1_555 A ASP 245 OD2 ? ? N CA 0 N ASP 324 1_555 ? ? ? ? ? ? ? 2.960 ? metalc3 metalc ? ? M CA . CA ? ? ? 1_555 A GLY 218 O ? ? N CA 0 N GLY 297 1_555 ? ? ? ? ? ? ? 1.627 ? metalc4 metalc ? ? M CA . CA ? ? ? 1_555 A ASP 214 O ? ? N CA 0 N ASP 293 1_555 ? ? ? ? ? ? ? 2.270 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ASN 246 A . ? ASN 325 N PRO 247 A ? PRO 326 N 1 -14.52 2 ARG 351 A . ? ARG 430 N PRO 352 A ? PRO 431 N 1 0.55 3 SER 7 B . ? SER 7 L PRO 8 B ? PRO 8 L 1 -9.05 4 PRO 94 B . ? PRO 94 L PRO 95 B ? PRO 95 L 1 -17.41 5 TYR 140 B . ? TYR 140 L PRO 141 B ? PRO 141 L 1 -3.64 6 PHE 153 C . ? PHE 148 H PRO 154 C ? PRO 149 H 1 -1.95 7 GLU 155 C . ? GLU 150 H PRO 156 C ? PRO 151 H 1 18.64 8 TRP 195 C . ? TRP 199 H PRO 196 C ? PRO 200 H 1 10.36 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 4 ? B ? 4 ? C ? 4 ? D ? 4 ? E ? 4 ? F ? 4 ? G ? 4 ? H ? 6 ? I ? 4 ? J ? 4 ? K ? 4 ? L ? 4 ? M ? 5 ? N ? 4 ? O ? 4 ? P ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel C 3 4 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel H 1 2 ? parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel L 1 2 ? anti-parallel L 2 3 ? anti-parallel M 1 2 ? anti-parallel M 2 3 ? anti-parallel M 3 4 ? anti-parallel M 4 5 ? parallel N 1 2 ? anti-parallel N 2 3 ? anti-parallel N 3 4 ? anti-parallel O 1 2 ? anti-parallel O 2 3 ? anti-parallel O 3 4 ? anti-parallel P 1 2 ? anti-parallel P 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 SER A 16 ? LYS A 22 ? SER N 96 LYS N 102 A 2 THR A 360 ? SER A 370 ? THR N 439 SER N 449 A 3 ALA A 341 ? GLY A 350 ? ALA N 420 GLY N 429 A 4 SER A 326 ? MET A 330 ? SER N 407 MET N 411 B 1 LEU A 35 ? CYS A 44 ? LEU N 115 CYS N 124 B 2 CYS A 49 ? THR A 59 ? CYS N 129 THR N 139 B 3 ALA A 77 ? PRO A 82 ? ALA N 157 PRO N 162 B 4 ARG A 93 ? CYS A 96 ? ARG N 172 CYS N 175 C 1 SER A 100 ? HIS A 105 ? SER N 179 HIS N 184 C 2 ARG A 110 ? SER A 116 ? ARG N 189 SER N 195 C 3 SER A 123 ? TYR A 128 ? SER N 202 TYR N 207 C 4 ARG A 131 ? ASN A 137 ? ARG N 210 ASN N 216 D 1 LEU A 144 ? THR A 146 ? LEU N 223 THR N 225 D 2 VAL A 157 ? GLY A 165 ? VAL N 236 GLY N 244 D 3 ALA A 171 ? LYS A 179 ? ALA N 250 LYS N 258 D 4 LYS A 182 ? PRO A 188 ? LYS N 261 PRO N 267 E 1 GLU A 197 ? GLU A 204 ? GLU N 276 GLU N 283 E 2 GLU A 207 ? ARG A 213 ? GLU N 286 ARG N 292 E 3 PRO A 222 ? ASP A 227 ? PRO N 301 ASP N 306 E 4 THR A 232 ? TYR A 237 ? THR N 311 TYR N 316 F 1 SER A 273 ? TYR A 274 ? SER N 353 TYR N 354 F 2 TRP A 281 ? ARG A 284 ? TRP N 361 ARG N 364 F 3 SER A 292 ? LYS A 298 ? SER N 372 LYS N 378 F 4 GLN A 312 ? TRP A 322 ? GLN N 392 TRP N 403 G 1 MET B 4 ? GLN B 6 ? MET L 4 GLN L 6 G 2 ARG B 18 ? ALA B 25 ? ARG L 18 ALA L 25 G 3 ASP B 70 ? SER B 76 ? ASP L 70 SER L 76 G 4 PHE B 62 ? SER B 67 ? PHE L 62 SER L 67 H 1 PHE B 10 ? THR B 13 ? PHE L 10 THR L 13 H 2 THR B 102 ? ILE B 106 ? THR L 102 ILE L 106 H 3 LEU B 85 ? GLN B 90 ? LEU L 85 GLN L 90 H 4 VAL B 33 ? GLN B 38 ? VAL L 33 GLN L 38 H 5 PRO B 44 ? TYR B 49 ? PRO L 44 TYR L 49 H 6 THR B 53 ? ARG B 54 ? THR L 53 ARG L 54 I 1 THR B 114 ? PHE B 118 ? THR L 114 PHE L 118 I 2 GLY B 129 ? PHE B 139 ? GLY L 129 PHE L 139 I 3 TYR B 173 ? THR B 182 ? TYR L 173 THR L 182 I 4 VAL B 159 ? THR B 164 ? VAL L 159 THR L 164 J 1 SER B 153 ? ARG B 155 ? SER L 153 ARG L 155 J 2 ILE B 144 ? ILE B 150 ? ILE L 144 ILE L 150 J 3 TYR B 192 ? HIS B 198 ? TYR L 192 HIS L 198 J 4 SER B 201 ? PHE B 209 ? SER L 201 PHE L 209 K 1 VAL C 5 ? GLN C 6 ? VAL H 5 GLN H 6 K 2 THR C 17 ? LYS C 23 ? THR H 17 LYS H 23 K 3 PHE C 68 ? GLU C 73 ? PHE H 67 GLU H 72 L 1 GLY C 44 ? ILE C 51 ? GLY H 44 ILE H 51 L 2 GLY C 33 ? ALA C 40 ? GLY H 33 ALA H 40 L 3 ALA C 92 ? GLY C 99 ? ALA H 88 GLY H 95 M 1 GLY C 44 ? ILE C 51 ? GLY H 44 ILE H 51 M 2 GLY C 33 ? ALA C 40 ? GLY H 33 ALA H 40 M 3 ALA C 92 ? GLY C 99 ? ALA H 88 GLY H 95 M 4 THR C 114 ? VAL C 118 ? THR H 107 VAL H 111 M 5 GLU C 10 ? LYS C 12 ? GLU H 10 LYS H 12 N 1 SER C 127 ? LEU C 131 ? SER H 120 LEU H 124 N 2 SER C 142 ? TYR C 152 ? SER H 137 TYR H 147 N 3 LEU C 181 ? THR C 191 ? LEU H 184 THR H 194 N 4 VAL C 170 ? THR C 172 ? VAL H 171 THR H 173 O 1 SER C 127 ? LEU C 131 ? SER H 120 LEU H 124 O 2 SER C 142 ? TYR C 152 ? SER H 137 TYR H 147 O 3 LEU C 181 ? THR C 191 ? LEU H 184 THR H 194 O 4 VAL C 176 ? GLN C 178 ? VAL H 177 GLN H 179 P 1 THR C 158 ? TRP C 161 ? THR H 153 TRP H 157 P 2 THR C 201 ? HIS C 206 ? THR H 206 HIS H 212 P 3 THR C 211 ? LYS C 216 ? THR H 217 LYS H 222 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 O GLY A 21 ? O GLY N 101 N SER A 366 ? N SER N 445 A 2 3 N SER A 369 ? N SER N 448 O ALA A 341 ? O ALA N 420 A 3 4 N TYR A 344 ? N TYR N 423 O GLY A 327 ? O GLY N 408 B 1 2 O SER A 43 ? O SER N 123 N ARG A 50 ? N ARG N 130 B 2 3 N SER A 55 ? N SER N 135 O ALA A 77 ? O ALA N 157 B 3 4 O SER A 80 ? O SER N 160 N ARG A 93 ? N ARG N 172 C 1 2 O CYS A 104 ? O CYS N 183 N MET A 111 ? N MET N 190 C 2 3 O SER A 116 ? O SER N 195 N SER A 123 ? N SER N 202 C 3 4 N TYR A 128 ? N TYR N 207 O ARG A 131 ? O ARG N 210 D 1 2 N ARG A 145 ? N ARG N 224 O THR A 163 ? O THR N 242 D 2 3 O ASP A 164 ? O ASP N 243 N GLU A 172 ? N GLU N 251 D 3 4 N LYS A 179 ? N LYS N 258 O LYS A 182 ? O LYS N 261 E 1 2 N GLU A 204 ? N GLU N 283 O GLU A 207 ? O GLU N 286 E 2 3 N CYS A 212 ? N CYS N 291 O PRO A 222 ? O PRO N 301 E 3 4 N ASP A 227 ? N ASP N 306 O THR A 232 ? O THR N 311 F 1 2 N TYR A 274 ? N TYR N 354 O TRP A 281 ? O TRP N 361 F 2 3 O ARG A 284 ? O ARG N 364 N GLU A 295 ? N GLU N 375 F 3 4 N LYS A 298 ? N LYS N 378 O GLN A 312 ? O GLN N 392 G 1 2 N THR B 5 ? N THR L 5 O LYS B 24 ? O LYS L 24 G 2 3 O CYS B 23 ? O CYS L 23 N TYR B 71 ? N TYR L 71 G 3 4 N THR B 74 ? N THR L 74 O ALA B 63 ? O ALA L 63 H 1 2 N MET B 11 ? N MET L 11 O LYS B 103 ? O LYS L 103 H 2 3 O THR B 102 ? O THR L 102 N TYR B 86 ? N TYR L 86 H 3 4 N GLN B 89 ? N GLN L 89 O VAL B 34 ? O VAL L 34 H 4 5 N GLN B 37 ? N GLN L 37 O LYS B 45 ? O LYS L 45 H 5 6 N TYR B 49 ? N TYR L 49 O THR B 53 ? O THR L 53 I 1 2 N PHE B 118 ? N PHE L 118 O VAL B 133 ? O VAL L 133 I 2 3 O PHE B 139 ? O PHE L 139 N TYR B 173 ? N TYR L 173 I 3 4 N THR B 178 ? N THR L 178 O LEU B 160 ? O LEU L 160 J 1 2 N ARG B 155 ? N ARG L 155 O TRP B 148 ? O TRP L 148 J 2 3 N LYS B 149 ? N LYS L 149 O THR B 193 ? O THR L 193 J 3 4 O HIS B 198 ? O HIS L 198 N SER B 201 ? N SER L 201 K 1 2 O VAL C 5 ? O VAL H 5 N LYS C 23 ? N LYS H 23 K 2 3 O GLN C 82 ? O GLN H 81 N ALA C 69 ? N ALA H 68 L 1 2 N ILE C 51 ? N ILE H 51 O MET C 34 ? O MET H 34 L 2 3 N GLN C 39 ? N GLN H 39 O THR C 93 ? O THR H 89 M 1 2 N ILE C 51 ? N ILE H 51 O MET C 34 ? O MET H 34 M 2 3 N GLN C 39 ? N GLN H 39 O THR C 93 ? O THR H 89 M 3 4 N PHE C 94 ? N PHE H 90 O THR C 114 ? O THR H 107 M 4 5 N THR C 117 ? N THR H 110 O GLU C 10 ? O GLU H 10 N 1 2 N LEU C 131 ? N LEU H 124 O GLY C 146 ? O GLY H 141 N 2 3 O TYR C 152 ? O TYR H 147 N TYR C 182 ? N TYR H 185 N 3 4 N SER C 187 ? N SER H 190 O HIS C 171 ? O HIS H 172 O 1 2 N LEU C 131 ? N LEU H 124 O GLY C 146 ? O GLY H 141 O 2 3 O TYR C 152 ? O TYR H 147 N TYR C 182 ? N TYR H 185 O 3 4 N THR C 183 ? N THR H 186 O VAL C 176 ? O VAL H 177 P 1 2 O THR C 160 ? O THR H 156 N ASN C 203 ? N ASN H 209 P 2 3 O HIS C 206 ? O HIS H 212 N THR C 211 ? N THR H 217 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG N 469A' AC2 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG N 470B' AC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE BMA N 471C' AC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE MAN N 472D' AC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE MAN N 473E' AC6 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE MAN N 474F' AC7 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG N 475A' AC8 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG N 476A' AC9 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG N 477B' BC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE CA N 0' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 6 HOH N . ? HOH N 70 . ? 3_545 ? 2 AC1 6 ASN A 120 ? ASN N 199 . ? 1_555 ? 3 AC1 6 ASN A 121 ? ASN N 200 . ? 1_555 ? 4 AC1 6 GLY A 375 ? GLY N 454 . ? 3_545 ? 5 AC1 6 GLN A 376 ? GLN N 455 . ? 3_545 ? 6 AC1 6 NAG E . B NAG N 470 . ? 1_555 ? 7 AC2 6 HOH N . ? HOH N 30 . ? 3_545 ? 8 AC2 6 GLN A 312 ? GLN N 392 . ? 3_545 ? 9 AC2 6 GLY A 313 ? GLY N 394 . ? 3_545 ? 10 AC2 6 PHE A 373 ? PHE N 452 . ? 3_545 ? 11 AC2 6 NAG D . A NAG N 469 . ? 1_555 ? 12 AC2 6 BMA F . C BMA N 471 . ? 1_555 ? 13 AC3 5 HOH N . ? HOH N 67 . ? 3_545 ? 14 AC3 5 THR A 311 ? THR N 391 . ? 3_545 ? 15 AC3 5 GLY A 313 ? GLY N 394 . ? 3_545 ? 16 AC3 5 NAG E . B NAG N 470 . ? 1_555 ? 17 AC3 5 MAN G . D MAN N 472 . ? 1_555 ? 18 AC4 4 ARG A 284 ? ARG N 364 . ? 3_545 ? 19 AC4 4 GLU A 295 ? GLU N 375 . ? 3_545 ? 20 AC4 4 BMA F . C BMA N 471 . ? 1_555 ? 21 AC4 4 MAN H . E MAN N 473 . ? 1_555 ? 22 AC5 6 ASP A 251 ? ASP N 330 . ? 3_545 ? 23 AC5 6 ARG A 284 ? ARG N 364 . ? 3_545 ? 24 AC5 6 LYS A 309 ? LYS N 389 . ? 3_545 ? 25 AC5 6 PRO A 310 ? PRO N 390 . ? 3_545 ? 26 AC5 6 MAN G . D MAN N 472 . ? 1_555 ? 27 AC5 6 MAN I . F MAN N 474 . ? 1_555 ? 28 AC6 7 ARG A 248 ? ARG N 327 . ? 3_545 ? 29 AC6 7 ASP A 250 ? ASP N 329 . ? 3_545 ? 30 AC6 7 ASP A 251 ? ASP N 330 . ? 3_545 ? 31 AC6 7 ARG A 284 ? ARG N 364 . ? 3_545 ? 32 AC6 7 ILE A 286 ? ILE N 366 . ? 3_545 ? 33 AC6 7 ILE A 288 ? ILE N 368 . ? 3_545 ? 34 AC6 7 MAN H . E MAN N 473 . ? 1_555 ? 35 AC7 3 ASP A 3 ? ASP N 83 . ? 1_555 ? 36 AC7 3 PHE A 4 ? PHE N 84 . ? 1_555 ? 37 AC7 3 ASN A 6 ? ASN N 86 . ? 1_555 ? 38 AC8 3 ASN A 66 ? ASN N 146 . ? 1_555 ? 39 AC8 3 TRP A 358 ? TRP N 437 . ? 1_555 ? 40 AC8 3 NAG L . B NAG N 477 . ? 1_555 ? 41 AC9 1 NAG K . A NAG N 476 . ? 1_555 ? 42 BC1 5 ASP A 214 ? ASP N 293 . ? 1_555 ? 43 BC1 5 GLY A 218 ? GLY N 297 . ? 1_555 ? 44 BC1 5 ASP A 245 ? ASP N 324 . ? 1_555 ? 45 BC1 5 ASN A 264 ? ASN N 344 . ? 1_555 ? 46 BC1 5 ASN A 267 ? ASN N 347 . ? 1_555 ? # _database_PDB_matrix.entry_id 1NCB _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 1NCB _atom_sites.fract_transf_matrix[1][1] 0.005988 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.005988 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.008065 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_sites_footnote.id _atom_sites_footnote.text 1 'RESIDUES PRO N 326, PRO N 431, PRO L 8, PRO L 95, PRO L 141, PRO H 149, PRO H 151 AND PRO H 200 ARE CIS PROLINES.' 2 ;THE COORDINATES OF THE CALCIUM ATOM ARE NOT WELL DETERMINED. THE REFERENCE STRUCTURE FOR THE CALCIUM ATOM IS THE N9 MUTANT S370L (PDB ENTRY 2NN9). ; # loop_ _atom_type.symbol C CA N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ILE A 1 1 ? 70.707 8.303 153.578 1.00 49.03 ? 81 ILE N N 1 ATOM 2 C CA . ILE A 1 1 ? 71.188 8.601 154.888 1.00 47.19 ? 81 ILE N CA 1 ATOM 3 C C . ILE A 1 1 ? 70.914 7.212 155.488 1.00 45.28 ? 81 ILE N C 1 ATOM 4 O O . ILE A 1 1 ? 71.036 6.254 154.708 1.00 45.78 ? 81 ILE N O 1 ATOM 5 C CB . ILE A 1 1 ? 70.348 9.906 155.360 1.00 47.40 ? 81 ILE N CB 1 ATOM 6 C CG1 . ILE A 1 1 ? 70.317 9.988 156.879 1.00 48.58 ? 81 ILE N CG1 1 ATOM 7 C CG2 . ILE A 1 1 ? 68.920 9.927 154.836 1.00 46.43 ? 81 ILE N CG2 1 ATOM 8 C CD1 . ILE A 1 1 ? 71.699 10.057 157.575 1.00 50.45 ? 81 ILE N CD1 1 ATOM 9 N N . ARG A 1 2 ? 70.654 6.967 156.765 1.00 41.64 ? 82 ARG N N 1 ATOM 10 C CA . ARG A 1 2 ? 70.388 5.626 157.243 1.00 36.91 ? 82 ARG N CA 1 ATOM 11 C C . ARG A 1 2 ? 69.151 5.954 158.049 1.00 33.27 ? 82 ARG N C 1 ATOM 12 O O . ARG A 1 2 ? 69.018 5.508 159.188 1.00 33.12 ? 82 ARG N O 1 ATOM 13 C CB . ARG A 1 2 ? 71.569 5.173 158.114 1.00 38.32 ? 82 ARG N CB 1 ATOM 14 C CG . ARG A 1 2 ? 71.623 3.672 158.376 1.00 38.93 ? 82 ARG N CG 1 ATOM 15 C CD . ARG A 1 2 ? 72.611 3.305 159.486 1.00 39.49 ? 82 ARG N CD 1 ATOM 16 N NE . ARG A 1 2 ? 74.000 3.641 159.197 1.00 39.92 ? 82 ARG N NE 1 ATOM 17 C CZ . ARG A 1 2 ? 74.832 2.820 158.545 1.00 40.13 ? 82 ARG N CZ 1 ATOM 18 N NH1 . ARG A 1 2 ? 74.439 1.642 158.059 1.00 40.49 ? 82 ARG N NH1 1 ATOM 19 N NH2 . ARG A 1 2 ? 76.087 3.214 158.354 1.00 39.98 ? 82 ARG N NH2 1 ATOM 20 N N . ASP A 1 3 ? 68.238 6.753 157.455 1.00 29.85 ? 83 ASP N N 1 ATOM 21 C CA . ASP A 1 3 ? 67.092 7.293 158.159 1.00 25.70 ? 83 ASP N CA 1 ATOM 22 C C . ASP A 1 3 ? 66.181 7.908 157.153 1.00 21.91 ? 83 ASP N C 1 ATOM 23 O O . ASP A 1 3 ? 66.673 8.459 156.167 1.00 21.63 ? 83 ASP N O 1 ATOM 24 C CB . ASP A 1 3 ? 67.513 8.365 159.123 1.00 27.22 ? 83 ASP N CB 1 ATOM 25 C CG . ASP A 1 3 ? 66.666 8.397 160.387 1.00 29.73 ? 83 ASP N CG 1 ATOM 26 O OD1 . ASP A 1 3 ? 65.804 7.528 160.599 1.00 32.87 ? 83 ASP N OD1 1 ATOM 27 O OD2 . ASP A 1 3 ? 66.881 9.315 161.181 1.00 31.03 ? 83 ASP N OD2 1 ATOM 28 N N . PHE A 1 4 ? 64.877 7.811 157.357 1.00 18.82 ? 84 PHE N N 1 ATOM 29 C CA . PHE A 1 4 ? 63.967 8.397 156.380 1.00 17.72 ? 84 PHE N CA 1 ATOM 30 C C . PHE A 1 4 ? 64.171 9.896 156.211 1.00 17.03 ? 84 PHE N C 1 ATOM 31 O O . PHE A 1 4 ? 64.791 10.558 157.037 1.00 17.81 ? 84 PHE N O 1 ATOM 32 C CB . PHE A 1 4 ? 62.527 8.143 156.767 1.00 14.67 ? 84 PHE N CB 1 ATOM 33 C CG . PHE A 1 4 ? 62.092 6.729 156.537 1.00 13.69 ? 84 PHE N CG 1 ATOM 34 C CD1 . PHE A 1 4 ? 62.205 6.152 155.303 1.00 13.17 ? 84 PHE N CD1 1 ATOM 35 C CD2 . PHE A 1 4 ? 61.527 6.025 157.563 1.00 13.85 ? 84 PHE N CD2 1 ATOM 36 C CE1 . PHE A 1 4 ? 61.744 4.862 155.086 1.00 12.13 ? 84 PHE N CE1 1 ATOM 37 C CE2 . PHE A 1 4 ? 61.062 4.743 157.346 1.00 13.37 ? 84 PHE N CE2 1 ATOM 38 C CZ . PHE A 1 4 ? 61.164 4.141 156.104 1.00 11.57 ? 84 PHE N CZ 1 ATOM 39 N N . ASN A 1 5 ? 63.731 10.435 155.092 1.00 16.39 ? 85 ASN N N 1 ATOM 40 C CA . ASN A 1 5 ? 63.901 11.842 154.807 1.00 16.87 ? 85 ASN N CA 1 ATOM 41 C C . ASN A 1 5 ? 62.616 12.579 155.104 1.00 16.39 ? 85 ASN N C 1 ATOM 42 O O . ASN A 1 5 ? 61.542 12.028 154.842 1.00 18.07 ? 85 ASN N O 1 ATOM 43 C CB . ASN A 1 5 ? 64.262 11.974 153.370 1.00 14.95 ? 85 ASN N CB 1 ATOM 44 C CG . ASN A 1 5 ? 64.614 13.375 152.958 1.00 14.49 ? 85 ASN N CG 1 ATOM 45 O OD1 . ASN A 1 5 ? 64.019 13.816 151.983 1.00 15.34 ? 85 ASN N OD1 1 ATOM 46 N ND2 . ASN A 1 5 ? 65.564 14.120 153.537 1.00 13.68 ? 85 ASN N ND2 1 ATOM 47 N N . ASN A 1 6 ? 62.661 13.791 155.662 1.00 15.34 ? 86 ASN N N 1 ATOM 48 C CA . ASN A 1 6 ? 61.446 14.547 155.956 1.00 16.65 ? 86 ASN N CA 1 ATOM 49 C C . ASN A 1 6 ? 61.559 15.843 155.241 1.00 13.76 ? 86 ASN N C 1 ATOM 50 O O . ASN A 1 6 ? 62.636 16.412 155.357 1.00 12.48 ? 86 ASN N O 1 ATOM 51 C CB . ASN A 1 6 ? 61.322 14.851 157.414 1.00 19.66 ? 86 ASN N CB 1 ATOM 52 C CG . ASN A 1 6 ? 60.929 13.634 158.164 1.00 24.97 ? 86 ASN N CG 1 ATOM 53 O OD1 . ASN A 1 6 ? 60.472 12.637 157.619 1.00 24.89 ? 86 ASN N OD1 1 ATOM 54 N ND2 . ASN A 1 6 ? 61.057 13.714 159.452 1.00 31.20 ? 86 ASN N ND2 1 ATOM 55 N N . LEU A 1 7 ? 60.594 16.384 154.530 1.00 7.91 ? 87 LEU N N 1 ATOM 56 C CA . LEU A 1 7 ? 60.965 17.564 153.767 1.00 7.03 ? 87 LEU N CA 1 ATOM 57 C C . LEU A 1 7 ? 60.765 18.633 154.823 1.00 6.42 ? 87 LEU N C 1 ATOM 58 O O . LEU A 1 7 ? 59.650 19.007 155.172 1.00 6.25 ? 87 LEU N O 1 ATOM 59 C CB . LEU A 1 7 ? 60.037 17.740 152.574 1.00 5.22 ? 87 LEU N CB 1 ATOM 60 C CG . LEU A 1 7 ? 59.535 16.440 151.914 1.00 5.88 ? 87 LEU N CG 1 ATOM 61 C CD1 . LEU A 1 7 ? 58.135 16.665 151.426 1.00 2.00 ? 87 LEU N CD1 1 ATOM 62 C CD2 . LEU A 1 7 ? 60.422 16.026 150.738 1.00 4.80 ? 87 LEU N CD2 1 ATOM 63 N N . THR A 1 8 ? 61.842 19.017 155.467 1.00 5.50 ? 88 THR N N 1 ATOM 64 C CA . THR A 1 8 ? 61.856 20.032 156.488 1.00 4.90 ? 88 THR N CA 1 ATOM 65 C C . THR A 1 8 ? 62.102 21.440 155.999 1.00 5.72 ? 88 THR N C 1 ATOM 66 O O . THR A 1 8 ? 61.899 22.369 156.771 1.00 8.56 ? 88 THR N O 1 ATOM 67 C CB . THR A 1 8 ? 62.930 19.725 157.497 1.00 5.83 ? 88 THR N CB 1 ATOM 68 O OG1 . THR A 1 8 ? 64.161 19.421 156.807 1.00 5.85 ? 88 THR N OG1 1 ATOM 69 C CG2 . THR A 1 8 ? 62.483 18.568 158.373 1.00 6.11 ? 88 THR N CG2 1 ATOM 70 N N . LYS A 1 9 ? 62.648 21.648 154.797 1.00 4.63 ? 89 LYS N N 1 ATOM 71 C CA . LYS A 1 9 ? 62.925 22.992 154.308 1.00 5.41 ? 89 LYS N CA 1 ATOM 72 C C . LYS A 1 9 ? 61.887 23.545 153.375 1.00 5.15 ? 89 LYS N C 1 ATOM 73 O O . LYS A 1 9 ? 60.858 22.929 153.123 1.00 7.38 ? 89 LYS N O 1 ATOM 74 C CB . LYS A 1 9 ? 64.246 23.058 153.568 1.00 4.85 ? 89 LYS N CB 1 ATOM 75 C CG . LYS A 1 9 ? 65.483 23.186 154.427 1.00 5.17 ? 89 LYS N CG 1 ATOM 76 C CD . LYS A 1 9 ? 66.178 21.931 154.886 1.00 3.68 ? 89 LYS N CD 1 ATOM 77 C CE . LYS A 1 9 ? 67.450 21.817 154.073 1.00 3.86 ? 89 LYS N CE 1 ATOM 78 N NZ . LYS A 1 9 ? 68.433 21.122 154.873 1.00 3.06 ? 89 LYS N NZ 1 ATOM 79 N N . GLY A 1 10 ? 62.122 24.773 152.959 1.00 3.96 ? 90 GLY N N 1 ATOM 80 C CA . GLY A 1 10 ? 61.340 25.403 151.913 1.00 2.42 ? 90 GLY N CA 1 ATOM 81 C C . GLY A 1 10 ? 62.268 25.630 150.727 1.00 2.81 ? 90 GLY N C 1 ATOM 82 O O . GLY A 1 10 ? 63.475 25.425 150.905 1.00 2.65 ? 90 GLY N O 1 ATOM 83 N N . LEU A 1 11 ? 61.756 25.948 149.529 1.00 2.00 ? 91 LEU N N 1 ATOM 84 C CA . LEU A 1 11 ? 62.609 26.284 148.388 1.00 3.40 ? 91 LEU N CA 1 ATOM 85 C C . LEU A 1 11 ? 63.501 27.499 148.641 1.00 3.72 ? 91 LEU N C 1 ATOM 86 O O . LEU A 1 11 ? 63.137 28.350 149.450 1.00 7.59 ? 91 LEU N O 1 ATOM 87 C CB . LEU A 1 11 ? 61.784 26.595 147.167 1.00 3.97 ? 91 LEU N CB 1 ATOM 88 C CG . LEU A 1 11 ? 60.849 25.543 146.670 1.00 2.74 ? 91 LEU N CG 1 ATOM 89 C CD1 . LEU A 1 11 ? 59.951 26.216 145.681 1.00 2.00 ? 91 LEU N CD1 1 ATOM 90 C CD2 . LEU A 1 11 ? 61.618 24.333 146.143 1.00 2.11 ? 91 LEU N CD2 1 ATOM 91 N N . CYS A 1 12 ? 64.649 27.638 147.957 1.00 4.03 ? 92 CYS N N 1 ATOM 92 C CA . CYS A 1 12 ? 65.524 28.796 148.188 1.00 6.85 ? 92 CYS N CA 1 ATOM 93 C C . CYS A 1 12 ? 65.002 29.905 147.276 1.00 5.68 ? 92 CYS N C 1 ATOM 94 O O . CYS A 1 12 ? 64.157 29.622 146.413 1.00 7.64 ? 92 CYS N O 1 ATOM 95 C CB . CYS A 1 12 ? 67.000 28.500 147.802 1.00 5.81 ? 92 CYS N CB 1 ATOM 96 S SG . CYS A 1 12 ? 67.886 27.107 148.559 1.00 3.90 ? 92 CYS N SG 1 ATOM 97 N N . THR A 1 13 ? 65.415 31.161 147.420 1.00 2.00 ? 93 THR N N 1 ATOM 98 C CA . THR A 1 13 ? 65.015 32.215 146.498 1.00 5.55 ? 93 THR N CA 1 ATOM 99 C C . THR A 1 13 ? 65.516 31.852 145.106 1.00 6.72 ? 93 THR N C 1 ATOM 100 O O . THR A 1 13 ? 66.721 31.609 144.952 1.00 9.76 ? 93 THR N O 1 ATOM 101 C CB . THR A 1 13 ? 65.628 33.548 146.910 1.00 5.12 ? 93 THR N CB 1 ATOM 102 O OG1 . THR A 1 13 ? 65.644 33.621 148.351 1.00 10.39 ? 93 THR N OG1 1 ATOM 103 C CG2 . THR A 1 13 ? 64.806 34.708 146.347 1.00 3.38 ? 93 THR N CG2 1 ATOM 104 N N . ILE A 1 14 ? 64.624 31.725 144.112 1.00 3.93 ? 94 ILE N N 1 ATOM 105 C CA . ILE A 1 14 ? 64.977 31.275 142.785 1.00 4.44 ? 94 ILE N CA 1 ATOM 106 C C . ILE A 1 14 ? 65.202 32.605 142.070 1.00 5.95 ? 94 ILE N C 1 ATOM 107 O O . ILE A 1 14 ? 64.207 33.268 141.735 1.00 8.75 ? 94 ILE N O 1 ATOM 108 C CB . ILE A 1 14 ? 63.801 30.536 142.089 1.00 5.71 ? 94 ILE N CB 1 ATOM 109 C CG1 . ILE A 1 14 ? 62.975 29.542 142.916 1.00 3.32 ? 94 ILE N CG1 1 ATOM 110 C CG2 . ILE A 1 14 ? 64.467 29.892 140.914 1.00 5.35 ? 94 ILE N CG2 1 ATOM 111 C CD1 . ILE A 1 14 ? 63.619 28.274 143.529 1.00 6.86 ? 94 ILE N CD1 1 ATOM 112 N N . ASN A 1 15 ? 66.423 33.093 141.841 1.00 5.40 ? 95 ASN N N 1 ATOM 113 C CA . ASN A 1 15 ? 66.567 34.327 141.076 1.00 3.13 ? 95 ASN N CA 1 ATOM 114 C C . ASN A 1 15 ? 67.083 34.175 139.670 1.00 3.96 ? 95 ASN N C 1 ATOM 115 O O . ASN A 1 15 ? 66.927 35.081 138.853 1.00 4.73 ? 95 ASN N O 1 ATOM 116 C CB . ASN A 1 15 ? 67.496 35.316 141.701 1.00 5.53 ? 95 ASN N CB 1 ATOM 117 C CG . ASN A 1 15 ? 66.999 35.904 143.008 1.00 4.48 ? 95 ASN N CG 1 ATOM 118 O OD1 . ASN A 1 15 ? 67.082 35.306 144.090 1.00 4.88 ? 95 ASN N OD1 1 ATOM 119 N ND2 . ASN A 1 15 ? 66.401 37.090 142.968 1.00 4.80 ? 95 ASN N ND2 1 ATOM 120 N N . SER A 1 16 ? 67.701 33.070 139.317 1.00 2.27 ? 96 SER N N 1 ATOM 121 C CA . SER A 1 16 ? 68.201 32.822 137.966 1.00 5.05 ? 96 SER N CA 1 ATOM 122 C C . SER A 1 16 ? 68.479 31.335 137.897 1.00 5.90 ? 96 SER N C 1 ATOM 123 O O . SER A 1 16 ? 68.068 30.632 138.834 1.00 9.57 ? 96 SER N O 1 ATOM 124 C CB . SER A 1 16 ? 69.490 33.610 137.720 1.00 6.32 ? 96 SER N CB 1 ATOM 125 O OG . SER A 1 16 ? 70.547 33.441 138.686 1.00 3.00 ? 96 SER N OG 1 ATOM 126 N N . TRP A 1 17 ? 69.184 30.762 136.918 1.00 5.11 ? 97 TRP N N 1 ATOM 127 C CA . TRP A 1 17 ? 69.367 29.306 136.867 1.00 4.97 ? 97 TRP N CA 1 ATOM 128 C C . TRP A 1 17 ? 70.825 28.976 136.561 1.00 3.45 ? 97 TRP N C 1 ATOM 129 O O . TRP A 1 17 ? 71.434 29.705 135.795 1.00 2.00 ? 97 TRP N O 1 ATOM 130 C CB . TRP A 1 17 ? 68.398 28.754 135.822 1.00 3.54 ? 97 TRP N CB 1 ATOM 131 C CG . TRP A 1 17 ? 66.950 28.929 136.284 1.00 4.63 ? 97 TRP N CG 1 ATOM 132 C CD1 . TRP A 1 17 ? 66.203 30.016 135.899 1.00 5.99 ? 97 TRP N CD1 1 ATOM 133 C CD2 . TRP A 1 17 ? 66.238 28.133 137.118 1.00 5.34 ? 97 TRP N CD2 1 ATOM 134 N NE1 . TRP A 1 17 ? 65.040 29.941 136.484 1.00 6.25 ? 97 TRP N NE1 1 ATOM 135 C CE2 . TRP A 1 17 ? 65.030 28.814 137.219 1.00 5.02 ? 97 TRP N CE2 1 ATOM 136 C CE3 . TRP A 1 17 ? 66.439 26.974 137.783 1.00 4.61 ? 97 TRP N CE3 1 ATOM 137 C CZ2 . TRP A 1 17 ? 63.991 28.351 137.988 1.00 3.34 ? 97 TRP N CZ2 1 ATOM 138 C CZ3 . TRP A 1 17 ? 65.405 26.508 138.553 1.00 6.79 ? 97 TRP N CZ3 1 ATOM 139 C CH2 . TRP A 1 17 ? 64.193 27.174 138.664 1.00 7.00 ? 97 TRP N CH2 1 ATOM 140 N N . HIS A 1 18 ? 71.503 28.017 137.156 1.00 4.39 ? 98 HIS N N 1 ATOM 141 C CA . HIS A 1 18 ? 72.894 27.746 136.774 1.00 6.32 ? 98 HIS N CA 1 ATOM 142 C C . HIS A 1 18 ? 72.878 26.322 136.200 1.00 6.01 ? 98 HIS N C 1 ATOM 143 O O . HIS A 1 18 ? 72.148 25.468 136.712 1.00 8.06 ? 98 HIS N O 1 ATOM 144 C CB . HIS A 1 18 ? 73.861 27.854 138.016 1.00 7.83 ? 98 HIS N CB 1 ATOM 145 C CG . HIS A 1 18 ? 73.728 26.708 138.993 1.00 8.16 ? 98 HIS N CG 1 ATOM 146 N ND1 . HIS A 1 18 ? 74.467 25.606 138.927 1.00 7.94 ? 98 HIS N ND1 1 ATOM 147 C CD2 . HIS A 1 18 ? 72.807 26.572 140.008 1.00 7.94 ? 98 HIS N CD2 1 ATOM 148 C CE1 . HIS A 1 18 ? 74.024 24.788 139.858 1.00 8.56 ? 98 HIS N CE1 1 ATOM 149 N NE2 . HIS A 1 18 ? 73.036 25.381 140.495 1.00 7.86 ? 98 HIS N NE2 1 ATOM 150 N N . ILE A 1 19 ? 73.526 26.017 135.058 1.00 6.30 ? 99 ILE N N 1 ATOM 151 C CA . ILE A 1 19 ? 73.609 24.616 134.599 1.00 4.98 ? 99 ILE N CA 1 ATOM 152 C C . ILE A 1 19 ? 74.214 23.679 135.611 1.00 4.58 ? 99 ILE N C 1 ATOM 153 O O . ILE A 1 19 ? 75.320 23.881 136.134 1.00 5.17 ? 99 ILE N O 1 ATOM 154 C CB . ILE A 1 19 ? 74.487 24.321 133.404 1.00 5.11 ? 99 ILE N CB 1 ATOM 155 C CG1 . ILE A 1 19 ? 75.446 25.465 133.207 1.00 3.67 ? 99 ILE N CG1 1 ATOM 156 C CG2 . ILE A 1 19 ? 73.580 23.854 132.275 1.00 4.13 ? 99 ILE N CG2 1 ATOM 157 C CD1 . ILE A 1 19 ? 76.839 25.128 133.674 1.00 4.13 ? 99 ILE N CD1 1 ATOM 158 N N . TYR A 1 20 ? 73.483 22.590 135.752 1.00 4.88 ? 100 TYR N N 1 ATOM 159 C CA . TYR A 1 20 ? 73.866 21.556 136.660 1.00 5.13 ? 100 TYR N CA 1 ATOM 160 C C . TYR A 1 20 ? 74.362 20.361 135.857 1.00 5.39 ? 100 TYR N C 1 ATOM 161 O O . TYR A 1 20 ? 75.417 19.809 136.165 1.00 5.87 ? 100 TYR N O 1 ATOM 162 C CB . TYR A 1 20 ? 72.621 21.281 137.503 1.00 5.52 ? 100 TYR N CB 1 ATOM 163 C CG . TYR A 1 20 ? 72.691 20.096 138.448 1.00 5.08 ? 100 TYR N CG 1 ATOM 164 C CD1 . TYR A 1 20 ? 73.355 20.192 139.647 1.00 4.78 ? 100 TYR N CD1 1 ATOM 165 C CD2 . TYR A 1 20 ? 72.126 18.909 138.058 1.00 4.01 ? 100 TYR N CD2 1 ATOM 166 C CE1 . TYR A 1 20 ? 73.468 19.102 140.477 1.00 4.73 ? 100 TYR N CE1 1 ATOM 167 C CE2 . TYR A 1 20 ? 72.240 17.816 138.872 1.00 5.82 ? 100 TYR N CE2 1 ATOM 168 C CZ . TYR A 1 20 ? 72.907 17.920 140.068 1.00 5.15 ? 100 TYR N CZ 1 ATOM 169 O OH . TYR A 1 20 ? 72.999 16.806 140.860 1.00 8.41 ? 100 TYR N OH 1 ATOM 170 N N . GLY A 1 21 ? 73.675 19.935 134.793 1.00 5.15 ? 101 GLY N N 1 ATOM 171 C CA . GLY A 1 21 ? 74.063 18.707 134.123 1.00 8.26 ? 101 GLY N CA 1 ATOM 172 C C . GLY A 1 21 ? 73.869 18.740 132.633 1.00 9.51 ? 101 GLY N C 1 ATOM 173 O O . GLY A 1 21 ? 72.870 19.271 132.123 1.00 7.63 ? 101 GLY N O 1 ATOM 174 N N . LYS A 1 22 ? 74.869 18.217 131.956 1.00 8.99 ? 102 LYS N N 1 ATOM 175 C CA . LYS A 1 22 ? 74.775 18.104 130.537 1.00 8.57 ? 102 LYS N CA 1 ATOM 176 C C . LYS A 1 22 ? 75.339 16.755 130.133 1.00 12.10 ? 102 LYS N C 1 ATOM 177 O O . LYS A 1 22 ? 76.458 16.398 130.477 1.00 13.89 ? 102 LYS N O 1 ATOM 178 C CB . LYS A 1 22 ? 75.579 19.147 129.802 1.00 7.29 ? 102 LYS N CB 1 ATOM 179 C CG . LYS A 1 22 ? 74.729 19.527 128.597 1.00 9.36 ? 102 LYS N CG 1 ATOM 180 C CD . LYS A 1 22 ? 75.245 20.609 127.620 1.00 7.53 ? 102 LYS N CD 1 ATOM 181 C CE . LYS A 1 22 ? 74.223 20.757 126.526 1.00 6.54 ? 102 LYS N CE 1 ATOM 182 N NZ . LYS A 1 22 ? 74.043 19.487 125.841 1.00 8.61 ? 102 LYS N NZ 1 ATOM 183 N N . ASP A 1 23 ? 74.515 16.043 129.357 1.00 14.99 ? 103 ASP N N 1 ATOM 184 C CA . ASP A 1 23 ? 74.672 14.720 128.743 1.00 13.94 ? 103 ASP N CA 1 ATOM 185 C C . ASP A 1 23 ? 75.535 14.587 127.463 1.00 13.84 ? 103 ASP N C 1 ATOM 186 O O . ASP A 1 23 ? 76.438 13.751 127.329 1.00 15.80 ? 103 ASP N O 1 ATOM 187 C CB . ASP A 1 23 ? 73.246 14.270 128.471 1.00 15.30 ? 103 ASP N CB 1 ATOM 188 C CG . ASP A 1 23 ? 72.951 12.794 128.556 1.00 17.17 ? 103 ASP N CG 1 ATOM 189 O OD1 . ASP A 1 23 ? 73.629 12.127 129.322 1.00 17.17 ? 103 ASP N OD1 1 ATOM 190 O OD2 . ASP A 1 23 ? 72.011 12.330 127.907 1.00 19.61 ? 103 ASP N OD2 1 ATOM 191 N N . ASN A 1 24 ? 75.169 15.378 126.435 1.00 12.88 ? 104 ASN N N 1 ATOM 192 C CA . ASN A 1 24 ? 75.704 15.381 125.069 1.00 10.06 ? 104 ASN N CA 1 ATOM 193 C C . ASN A 1 24 ? 75.639 14.026 124.384 1.00 9.24 ? 104 ASN N C 1 ATOM 194 O O . ASN A 1 24 ? 76.199 13.754 123.325 1.00 9.62 ? 104 ASN N O 1 ATOM 195 C CB . ASN A 1 24 ? 77.129 15.863 125.074 1.00 12.06 ? 104 ASN N CB 1 ATOM 196 C CG . ASN A 1 24 ? 77.245 17.364 125.220 1.00 13.32 ? 104 ASN N CG 1 ATOM 197 O OD1 . ASN A 1 24 ? 76.518 18.146 124.643 1.00 16.85 ? 104 ASN N OD1 1 ATOM 198 N ND2 . ASN A 1 24 ? 78.165 17.845 126.027 1.00 11.46 ? 104 ASN N ND2 1 ATOM 199 N N . ALA A 1 25 ? 74.743 13.209 124.922 1.00 6.22 ? 105 ALA N N 1 ATOM 200 C CA . ALA A 1 25 ? 74.476 11.838 124.543 1.00 4.44 ? 105 ALA N CA 1 ATOM 201 C C . ALA A 1 25 ? 74.324 11.542 123.078 1.00 5.50 ? 105 ALA N C 1 ATOM 202 O O . ALA A 1 25 ? 74.926 10.565 122.615 1.00 6.23 ? 105 ALA N O 1 ATOM 203 C CB . ALA A 1 25 ? 73.214 11.338 125.144 1.00 2.00 ? 105 ALA N CB 1 ATOM 204 N N . VAL A 1 26 ? 73.524 12.355 122.338 1.00 4.05 ? 106 VAL N N 1 ATOM 205 C CA . VAL A 1 26 ? 73.367 12.090 120.919 1.00 2.00 ? 106 VAL N CA 1 ATOM 206 C C . VAL A 1 26 ? 74.682 12.434 120.245 1.00 3.46 ? 106 VAL N C 1 ATOM 207 O O . VAL A 1 26 ? 75.110 11.645 119.416 1.00 3.94 ? 106 VAL N O 1 ATOM 208 C CB . VAL A 1 26 ? 72.165 12.892 120.344 1.00 2.47 ? 106 VAL N CB 1 ATOM 209 C CG1 . VAL A 1 26 ? 71.964 12.671 118.843 1.00 2.00 ? 106 VAL N CG1 1 ATOM 210 C CG2 . VAL A 1 26 ? 70.914 12.380 120.997 1.00 3.47 ? 106 VAL N CG2 1 ATOM 211 N N . ARG A 1 27 ? 75.425 13.500 120.623 1.00 4.36 ? 107 ARG N N 1 ATOM 212 C CA . ARG A 1 27 ? 76.639 13.892 119.905 1.00 2.00 ? 107 ARG N CA 1 ATOM 213 C C . ARG A 1 27 ? 77.668 12.816 120.088 1.00 4.42 ? 107 ARG N C 1 ATOM 214 O O . ARG A 1 27 ? 78.337 12.420 119.130 1.00 6.28 ? 107 ARG N O 1 ATOM 215 C CB . ARG A 1 27 ? 77.306 15.141 120.421 1.00 2.70 ? 107 ARG N CB 1 ATOM 216 C CG . ARG A 1 27 ? 76.424 16.342 120.579 1.00 2.48 ? 107 ARG N CG 1 ATOM 217 C CD . ARG A 1 27 ? 77.160 17.576 120.091 1.00 2.00 ? 107 ARG N CD 1 ATOM 218 N NE . ARG A 1 27 ? 78.324 17.889 120.864 1.00 2.00 ? 107 ARG N NE 1 ATOM 219 C CZ . ARG A 1 27 ? 79.450 18.167 120.251 1.00 2.76 ? 107 ARG N CZ 1 ATOM 220 N NH1 . ARG A 1 27 ? 79.509 18.570 119.006 1.00 3.98 ? 107 ARG N NH1 1 ATOM 221 N NH2 . ARG A 1 27 ? 80.539 18.188 120.969 1.00 4.94 ? 107 ARG N NH2 1 ATOM 222 N N . ILE A 1 28 ? 77.801 12.313 121.312 1.00 5.54 ? 108 ILE N N 1 ATOM 223 C CA . ILE A 1 28 ? 78.817 11.293 121.563 1.00 4.89 ? 108 ILE N CA 1 ATOM 224 C C . ILE A 1 28 ? 78.354 9.950 120.965 1.00 5.97 ? 108 ILE N C 1 ATOM 225 O O . ILE A 1 28 ? 79.144 9.272 120.318 1.00 8.22 ? 108 ILE N O 1 ATOM 226 C CB . ILE A 1 28 ? 79.041 11.266 123.077 1.00 4.92 ? 108 ILE N CB 1 ATOM 227 C CG1 . ILE A 1 28 ? 79.353 12.633 123.557 1.00 2.00 ? 108 ILE N CG1 1 ATOM 228 C CG2 . ILE A 1 28 ? 80.245 10.424 123.445 1.00 4.83 ? 108 ILE N CG2 1 ATOM 229 C CD1 . ILE A 1 28 ? 79.095 12.648 125.056 1.00 3.13 ? 108 ILE N CD1 1 ATOM 230 N N . GLY A 1 29 ? 77.084 9.553 121.090 1.00 7.84 ? 109 GLY N N 1 ATOM 231 C CA . GLY A 1 29 ? 76.463 8.387 120.464 1.00 7.30 ? 109 GLY N CA 1 ATOM 232 C C . GLY A 1 29 ? 76.582 8.227 118.955 1.00 9.53 ? 109 GLY N C 1 ATOM 233 O O . GLY A 1 29 ? 76.207 7.170 118.427 1.00 11.17 ? 109 GLY N O 1 ATOM 234 N N . GLU A 1 30 ? 77.129 9.202 118.223 1.00 10.88 ? 110 GLU N N 1 ATOM 235 C CA . GLU A 1 30 ? 77.324 9.034 116.808 1.00 10.35 ? 110 GLU N CA 1 ATOM 236 C C . GLU A 1 30 ? 78.593 8.226 116.705 1.00 12.50 ? 110 GLU N C 1 ATOM 237 O O . GLU A 1 30 ? 78.875 7.715 115.635 1.00 15.49 ? 110 GLU N O 1 ATOM 238 C CB . GLU A 1 30 ? 77.473 10.376 116.110 1.00 9.97 ? 110 GLU N CB 1 ATOM 239 C CG . GLU A 1 30 ? 77.623 10.257 114.570 1.00 8.63 ? 110 GLU N CG 1 ATOM 240 C CD . GLU A 1 30 ? 79.062 10.148 114.051 1.00 6.72 ? 110 GLU N CD 1 ATOM 241 O OE1 . GLU A 1 30 ? 79.906 10.650 114.784 1.00 5.71 ? 110 GLU N OE1 1 ATOM 242 O OE2 . GLU A 1 30 ? 79.353 9.603 112.970 1.00 6.91 ? 110 GLU N OE2 1 ATOM 243 N N . ASP A 1 31 ? 79.437 8.080 117.725 1.00 13.36 ? 111 ASP N N 1 ATOM 244 C CA . ASP A 1 31 ? 80.578 7.180 117.636 1.00 16.30 ? 111 ASP N CA 1 ATOM 245 C C . ASP A 1 31 ? 80.902 6.543 118.979 1.00 14.87 ? 111 ASP N C 1 ATOM 246 O O . ASP A 1 31 ? 82.048 6.442 119.413 1.00 19.43 ? 111 ASP N O 1 ATOM 247 C CB . ASP A 1 31 ? 81.785 7.960 117.079 1.00 16.90 ? 111 ASP N CB 1 ATOM 248 C CG . ASP A 1 31 ? 82.962 7.127 116.545 1.00 19.11 ? 111 ASP N CG 1 ATOM 249 O OD1 . ASP A 1 31 ? 82.827 6.531 115.471 1.00 18.31 ? 111 ASP N OD1 1 ATOM 250 O OD2 . ASP A 1 31 ? 84.016 7.102 117.193 1.00 22.03 ? 111 ASP N OD2 1 ATOM 251 N N . SER A 1 32 ? 79.902 6.165 119.741 1.00 10.49 ? 112 SER N N 1 ATOM 252 C CA . SER A 1 32 ? 80.132 5.425 120.972 1.00 9.35 ? 112 SER N CA 1 ATOM 253 C C . SER A 1 32 ? 78.919 4.524 121.185 1.00 7.80 ? 112 SER N C 1 ATOM 254 O O . SER A 1 32 ? 77.838 4.803 120.623 1.00 8.93 ? 112 SER N O 1 ATOM 255 C CB . SER A 1 32 ? 80.303 6.414 122.132 1.00 9.55 ? 112 SER N CB 1 ATOM 256 O OG . SER A 1 32 ? 81.244 7.392 121.731 1.00 13.44 ? 112 SER N OG 1 ATOM 257 N N . ASP A 1 33 ? 79.030 3.470 122.004 1.00 5.66 ? 113 ASP N N 1 ATOM 258 C CA . ASP A 1 33 ? 77.939 2.523 122.160 1.00 5.79 ? 113 ASP N CA 1 ATOM 259 C C . ASP A 1 33 ? 76.901 3.121 123.125 1.00 3.93 ? 113 ASP N C 1 ATOM 260 O O . ASP A 1 33 ? 76.809 2.716 124.292 1.00 3.39 ? 113 ASP N O 1 ATOM 261 C CB . ASP A 1 33 ? 78.571 1.135 122.627 1.00 5.30 ? 113 ASP N CB 1 ATOM 262 C CG . ASP A 1 33 ? 79.421 0.425 121.533 1.00 7.20 ? 113 ASP N CG 1 ATOM 263 O OD1 . ASP A 1 33 ? 79.117 0.487 120.336 1.00 8.95 ? 113 ASP N OD1 1 ATOM 264 O OD2 . ASP A 1 33 ? 80.430 -0.193 121.838 1.00 5.21 ? 113 ASP N OD2 1 ATOM 265 N N . VAL A 1 34 ? 76.145 4.123 122.637 1.00 2.00 ? 114 VAL N N 1 ATOM 266 C CA . VAL A 1 34 ? 75.120 4.838 123.389 1.00 3.81 ? 114 VAL N CA 1 ATOM 267 C C . VAL A 1 34 ? 73.711 4.266 123.154 1.00 4.47 ? 114 VAL N C 1 ATOM 268 O O . VAL A 1 34 ? 73.347 3.809 122.063 1.00 3.92 ? 114 VAL N O 1 ATOM 269 C CB . VAL A 1 34 ? 75.152 6.325 122.998 1.00 2.00 ? 114 VAL N CB 1 ATOM 270 C CG1 . VAL A 1 34 ? 74.042 7.149 123.644 1.00 2.00 ? 114 VAL N CG1 1 ATOM 271 C CG2 . VAL A 1 34 ? 76.390 6.892 123.552 1.00 2.22 ? 114 VAL N CG2 1 ATOM 272 N N . LEU A 1 35 ? 72.900 4.305 124.208 1.00 4.62 ? 115 LEU N N 1 ATOM 273 C CA . LEU A 1 35 ? 71.535 3.816 124.193 1.00 2.82 ? 115 LEU N CA 1 ATOM 274 C C . LEU A 1 35 ? 70.559 4.881 123.743 1.00 2.00 ? 115 LEU N C 1 ATOM 275 O O . LEU A 1 35 ? 70.764 6.087 123.881 1.00 2.00 ? 115 LEU N O 1 ATOM 276 C CB . LEU A 1 35 ? 71.161 3.301 125.588 1.00 2.32 ? 115 LEU N CB 1 ATOM 277 C CG . LEU A 1 35 ? 71.825 2.084 126.179 1.00 2.00 ? 115 LEU N CG 1 ATOM 278 C CD1 . LEU A 1 35 ? 70.793 1.372 127.017 1.00 4.06 ? 115 LEU N CD1 1 ATOM 279 C CD2 . LEU A 1 35 ? 72.117 1.025 125.171 1.00 2.53 ? 115 LEU N CD2 1 ATOM 280 N N . VAL A 1 36 ? 69.507 4.387 123.134 1.00 3.93 ? 116 VAL N N 1 ATOM 281 C CA . VAL A 1 36 ? 68.446 5.194 122.563 1.00 4.06 ? 116 VAL N CA 1 ATOM 282 C C . VAL A 1 36 ? 67.517 5.176 123.764 1.00 2.14 ? 116 VAL N C 1 ATOM 283 O O . VAL A 1 36 ? 67.265 4.151 124.392 1.00 2.88 ? 116 VAL N O 1 ATOM 284 C CB . VAL A 1 36 ? 67.757 4.509 121.336 1.00 3.12 ? 116 VAL N CB 1 ATOM 285 C CG1 . VAL A 1 36 ? 66.970 5.553 120.554 1.00 2.48 ? 116 VAL N CG1 1 ATOM 286 C CG2 . VAL A 1 36 ? 68.751 3.911 120.402 1.00 2.38 ? 116 VAL N CG2 1 ATOM 287 N N . THR A 1 37 ? 67.116 6.365 124.139 1.00 4.31 ? 117 THR N N 1 ATOM 288 C CA . THR A 1 37 ? 66.291 6.547 125.269 1.00 5.33 ? 117 THR N CA 1 ATOM 289 C C . THR A 1 37 ? 65.315 7.634 124.856 1.00 4.22 ? 117 THR N C 1 ATOM 290 O O . THR A 1 37 ? 65.318 8.257 123.783 1.00 2.00 ? 117 THR N O 1 ATOM 291 C CB . THR A 1 37 ? 67.145 6.990 126.460 1.00 6.15 ? 117 THR N CB 1 ATOM 292 O OG1 . THR A 1 37 ? 67.556 8.318 126.152 1.00 11.31 ? 117 THR N OG1 1 ATOM 293 C CG2 . THR A 1 37 ? 68.362 6.105 126.740 1.00 6.91 ? 117 THR N CG2 1 ATOM 294 N N . ARG A 1 38 ? 64.463 7.816 125.828 1.00 4.57 ? 118 ARG N N 1 ATOM 295 C CA . ARG A 1 38 ? 63.512 8.887 125.849 1.00 6.23 ? 118 ARG N CA 1 ATOM 296 C C . ARG A 1 38 ? 62.936 8.817 127.280 1.00 7.05 ? 118 ARG N C 1 ATOM 297 O O . ARG A 1 38 ? 63.249 7.916 128.099 1.00 11.78 ? 118 ARG N O 1 ATOM 298 C CB . ARG A 1 38 ? 62.480 8.632 124.768 1.00 6.33 ? 118 ARG N CB 1 ATOM 299 C CG . ARG A 1 38 ? 62.515 9.470 123.536 1.00 6.13 ? 118 ARG N CG 1 ATOM 300 C CD . ARG A 1 38 ? 61.678 10.672 123.880 1.00 7.30 ? 118 ARG N CD 1 ATOM 301 N NE . ARG A 1 38 ? 60.389 10.824 123.229 1.00 9.11 ? 118 ARG N NE 1 ATOM 302 C CZ . ARG A 1 38 ? 59.507 11.668 123.731 1.00 8.64 ? 118 ARG N CZ 1 ATOM 303 N NH1 . ARG A 1 38 ? 59.538 12.048 124.991 1.00 9.03 ? 118 ARG N NH1 1 ATOM 304 N NH2 . ARG A 1 38 ? 58.422 11.943 123.065 1.00 9.44 ? 118 ARG N NH2 1 ATOM 305 N N . GLU A 1 39 ? 62.077 9.802 127.561 1.00 7.05 ? 119 GLU N N 1 ATOM 306 C CA . GLU A 1 39 ? 61.441 10.010 128.842 1.00 4.26 ? 119 GLU N CA 1 ATOM 307 C C . GLU A 1 39 ? 62.488 10.102 129.918 1.00 2.00 ? 119 GLU N C 1 ATOM 308 O O . GLU A 1 39 ? 62.430 9.362 130.879 1.00 2.00 ? 119 GLU N O 1 ATOM 309 C CB . GLU A 1 39 ? 60.474 8.883 129.164 1.00 5.88 ? 119 GLU N CB 1 ATOM 310 C CG . GLU A 1 39 ? 59.267 8.867 128.273 1.00 8.63 ? 119 GLU N CG 1 ATOM 311 C CD . GLU A 1 39 ? 59.595 8.277 126.926 1.00 9.21 ? 119 GLU N CD 1 ATOM 312 O OE1 . GLU A 1 39 ? 60.288 7.271 126.878 1.00 9.40 ? 119 GLU N OE1 1 ATOM 313 O OE2 . GLU A 1 39 ? 59.159 8.791 125.914 1.00 10.17 ? 119 GLU N OE2 1 ATOM 314 N N . PRO A 1 40 ? 63.481 10.963 129.828 1.00 2.00 ? 120 PRO N N 1 ATOM 315 C CA . PRO A 1 40 ? 64.598 10.979 130.743 1.00 4.33 ? 120 PRO N CA 1 ATOM 316 C C . PRO A 1 40 ? 64.204 11.575 132.074 1.00 3.90 ? 120 PRO N C 1 ATOM 317 O O . PRO A 1 40 ? 63.116 12.102 132.148 1.00 8.11 ? 120 PRO N O 1 ATOM 318 C CB . PRO A 1 40 ? 65.646 11.760 129.982 1.00 2.29 ? 120 PRO N CB 1 ATOM 319 C CG . PRO A 1 40 ? 64.796 12.853 129.444 1.00 2.10 ? 120 PRO N CG 1 ATOM 320 C CD . PRO A 1 40 ? 63.594 12.087 128.929 1.00 2.00 ? 120 PRO N CD 1 ATOM 321 N N . TYR A 1 41 ? 65.000 11.487 133.124 1.00 4.17 ? 121 TYR N N 1 ATOM 322 C CA . TYR A 1 41 ? 64.811 12.286 134.304 1.00 5.86 ? 121 TYR N CA 1 ATOM 323 C C . TYR A 1 41 ? 66.038 12.265 135.196 1.00 3.97 ? 121 TYR N C 1 ATOM 324 O O . TYR A 1 41 ? 67.094 11.830 134.726 1.00 3.96 ? 121 TYR N O 1 ATOM 325 C CB . TYR A 1 41 ? 63.558 11.881 135.133 1.00 3.95 ? 121 TYR N CB 1 ATOM 326 C CG . TYR A 1 41 ? 63.209 10.499 135.561 1.00 2.60 ? 121 TYR N CG 1 ATOM 327 C CD1 . TYR A 1 41 ? 62.436 9.735 134.757 1.00 2.81 ? 121 TYR N CD1 1 ATOM 328 C CD2 . TYR A 1 41 ? 63.639 10.033 136.772 1.00 3.72 ? 121 TYR N CD2 1 ATOM 329 C CE1 . TYR A 1 41 ? 62.103 8.478 135.168 1.00 3.12 ? 121 TYR N CE1 1 ATOM 330 C CE2 . TYR A 1 41 ? 63.314 8.778 137.194 1.00 2.01 ? 121 TYR N CE2 1 ATOM 331 C CZ . TYR A 1 41 ? 62.539 8.029 136.377 1.00 2.00 ? 121 TYR N CZ 1 ATOM 332 O OH . TYR A 1 41 ? 62.177 6.782 136.792 1.00 2.15 ? 121 TYR N OH 1 ATOM 333 N N . VAL A 1 42 ? 65.982 12.880 136.392 1.00 5.01 ? 122 VAL N N 1 ATOM 334 C CA . VAL A 1 42 ? 67.094 12.936 137.344 1.00 5.06 ? 122 VAL N CA 1 ATOM 335 C C . VAL A 1 42 ? 66.522 12.798 138.755 1.00 6.43 ? 122 VAL N C 1 ATOM 336 O O . VAL A 1 42 ? 65.581 13.491 139.150 1.00 7.81 ? 122 VAL N O 1 ATOM 337 C CB . VAL A 1 42 ? 67.884 14.265 137.292 1.00 4.78 ? 122 VAL N CB 1 ATOM 338 C CG1 . VAL A 1 42 ? 69.060 14.183 138.265 1.00 4.02 ? 122 VAL N CG1 1 ATOM 339 C CG2 . VAL A 1 42 ? 68.381 14.537 135.870 1.00 3.49 ? 122 VAL N CG2 1 ATOM 340 N N . SER A 1 43 ? 67.150 11.923 139.543 1.00 7.56 ? 123 SER N N 1 ATOM 341 C CA . SER A 1 43 ? 66.801 11.634 140.904 1.00 7.50 ? 123 SER N CA 1 ATOM 342 C C . SER A 1 43 ? 68.113 11.540 141.657 1.00 8.76 ? 123 SER N C 1 ATOM 343 O O . SER A 1 43 ? 69.174 11.218 141.093 1.00 9.36 ? 123 SER N O 1 ATOM 344 C CB . SER A 1 43 ? 66.068 10.337 140.965 1.00 9.05 ? 123 SER N CB 1 ATOM 345 O OG . SER A 1 43 ? 65.509 10.167 142.243 1.00 7.48 ? 123 SER N OG 1 ATOM 346 N N . CYS A 1 44 ? 68.055 11.865 142.944 1.00 10.85 ? 124 CYS N N 1 ATOM 347 C CA . CYS A 1 44 ? 69.216 11.804 143.799 1.00 10.06 ? 124 CYS N CA 1 ATOM 348 C C . CYS A 1 44 ? 68.957 10.832 144.924 1.00 6.60 ? 124 CYS N C 1 ATOM 349 O O . CYS A 1 44 ? 67.813 10.614 145.330 1.00 6.68 ? 124 CYS N O 1 ATOM 350 C CB . CYS A 1 44 ? 69.534 13.154 144.413 1.00 9.63 ? 124 CYS N CB 1 ATOM 351 S SG . CYS A 1 44 ? 69.943 14.505 143.276 1.00 8.80 ? 124 CYS N SG 1 ATOM 352 N N . ASP A 1 45 ? 70.053 10.136 145.201 1.00 7.94 ? 125 ASP N N 1 ATOM 353 C CA . ASP A 1 45 ? 70.262 9.272 146.343 1.00 8.46 ? 125 ASP N CA 1 ATOM 354 C C . ASP A 1 45 ? 70.863 10.196 147.378 1.00 7.74 ? 125 ASP N C 1 ATOM 355 O O . ASP A 1 45 ? 71.349 11.260 147.022 1.00 7.67 ? 125 ASP N O 1 ATOM 356 C CB . ASP A 1 45 ? 71.300 8.196 146.109 1.00 9.96 ? 125 ASP N CB 1 ATOM 357 C CG . ASP A 1 45 ? 70.950 6.994 145.245 1.00 11.78 ? 125 ASP N CG 1 ATOM 358 O OD1 . ASP A 1 45 ? 69.804 6.853 144.819 1.00 15.33 ? 125 ASP N OD1 1 ATOM 359 O OD2 . ASP A 1 45 ? 71.852 6.188 145.004 1.00 13.32 ? 125 ASP N OD2 1 ATOM 360 N N . PRO A 1 46 ? 70.960 9.872 148.664 1.00 11.12 ? 126 PRO N N 1 ATOM 361 C CA . PRO A 1 46 ? 71.755 10.598 149.665 1.00 12.25 ? 126 PRO N CA 1 ATOM 362 C C . PRO A 1 46 ? 73.187 10.902 149.224 1.00 12.77 ? 126 PRO N C 1 ATOM 363 O O . PRO A 1 46 ? 73.774 11.969 149.390 1.00 12.36 ? 126 PRO N O 1 ATOM 364 C CB . PRO A 1 46 ? 71.654 9.695 150.862 1.00 10.14 ? 126 PRO N CB 1 ATOM 365 C CG . PRO A 1 46 ? 70.246 9.202 150.767 1.00 9.52 ? 126 PRO N CG 1 ATOM 366 C CD . PRO A 1 46 ? 70.125 8.892 149.319 1.00 12.03 ? 126 PRO N CD 1 ATOM 367 N N . ASP A 1 47 ? 73.657 9.843 148.604 1.00 17.70 ? 127 ASP N N 1 ATOM 368 C CA . ASP A 1 47 ? 74.943 9.763 148.011 1.00 20.43 ? 127 ASP N CA 1 ATOM 369 C C . ASP A 1 47 ? 75.357 10.424 146.698 1.00 19.79 ? 127 ASP N C 1 ATOM 370 O O . ASP A 1 47 ? 76.498 10.857 146.550 1.00 19.75 ? 127 ASP N O 1 ATOM 371 C CB . ASP A 1 47 ? 75.101 8.313 147.991 1.00 23.93 ? 127 ASP N CB 1 ATOM 372 C CG . ASP A 1 47 ? 76.416 7.919 148.562 1.00 28.41 ? 127 ASP N CG 1 ATOM 373 O OD1 . ASP A 1 47 ? 77.041 8.716 149.286 1.00 28.28 ? 127 ASP N OD1 1 ATOM 374 O OD2 . ASP A 1 47 ? 76.782 6.776 148.256 1.00 32.28 ? 127 ASP N OD2 1 ATOM 375 N N . GLU A 1 48 ? 74.484 10.426 145.696 1.00 19.45 ? 128 GLU N N 1 ATOM 376 C CA . GLU A 1 48 ? 74.797 10.882 144.361 1.00 19.91 ? 128 GLU N CA 1 ATOM 377 C C . GLU A 1 48 ? 73.562 11.190 143.554 1.00 17.18 ? 128 GLU N C 1 ATOM 378 O O . GLU A 1 48 ? 72.493 10.693 143.908 1.00 17.94 ? 128 GLU N O 1 ATOM 379 C CB . GLU A 1 48 ? 75.571 9.824 143.592 1.00 19.86 ? 128 GLU N CB 1 ATOM 380 C CG . GLU A 1 48 ? 74.953 8.476 143.266 1.00 21.34 ? 128 GLU N CG 1 ATOM 381 C CD . GLU A 1 48 ? 75.853 7.602 142.393 1.00 22.27 ? 128 GLU N CD 1 ATOM 382 O OE1 . GLU A 1 48 ? 75.908 7.821 141.177 1.00 21.93 ? 128 GLU N OE1 1 ATOM 383 O OE2 . GLU A 1 48 ? 76.507 6.701 142.927 1.00 24.70 ? 128 GLU N OE2 1 ATOM 384 N N . CYS A 1 49 ? 73.661 11.979 142.475 1.00 14.68 ? 129 CYS N N 1 ATOM 385 C CA . CYS A 1 49 ? 72.522 12.191 141.589 1.00 9.98 ? 129 CYS N CA 1 ATOM 386 C C . CYS A 1 49 ? 72.844 11.515 140.279 1.00 8.52 ? 129 CYS N C 1 ATOM 387 O O . CYS A 1 49 ? 74.030 11.377 139.926 1.00 5.48 ? 129 CYS N O 1 ATOM 388 C CB . CYS A 1 49 ? 72.282 13.659 141.371 1.00 10.63 ? 129 CYS N CB 1 ATOM 389 S SG . CYS A 1 49 ? 71.911 14.344 142.998 1.00 10.46 ? 129 CYS N SG 1 ATOM 390 N N . ARG A 1 50 ? 71.794 11.025 139.623 1.00 6.80 ? 130 ARG N N 1 ATOM 391 C CA . ARG A 1 50 ? 71.974 10.232 138.410 1.00 4.91 ? 130 ARG N CA 1 ATOM 392 C C . ARG A 1 50 ? 70.887 10.575 137.390 1.00 5.05 ? 130 ARG N C 1 ATOM 393 O O . ARG A 1 50 ? 69.842 11.172 137.723 1.00 5.49 ? 130 ARG N O 1 ATOM 394 C CB . ARG A 1 50 ? 71.917 8.733 138.731 1.00 3.52 ? 130 ARG N CB 1 ATOM 395 C CG . ARG A 1 50 ? 73.115 8.300 139.513 1.00 6.08 ? 130 ARG N CG 1 ATOM 396 C CD . ARG A 1 50 ? 72.912 6.914 140.104 1.00 5.72 ? 130 ARG N CD 1 ATOM 397 N NE . ARG A 1 50 ? 72.813 5.933 139.047 1.00 3.51 ? 130 ARG N NE 1 ATOM 398 C CZ . ARG A 1 50 ? 73.842 5.217 138.640 1.00 3.83 ? 130 ARG N CZ 1 ATOM 399 N NH1 . ARG A 1 50 ? 74.973 5.245 139.330 1.00 3.65 ? 130 ARG N NH1 1 ATOM 400 N NH2 . ARG A 1 50 ? 73.695 4.412 137.594 1.00 4.00 ? 130 ARG N NH2 1 ATOM 401 N N . PHE A 1 51 ? 71.179 10.263 136.132 1.00 5.57 ? 131 PHE N N 1 ATOM 402 C CA . PHE A 1 51 ? 70.270 10.508 135.044 1.00 2.79 ? 131 PHE N CA 1 ATOM 403 C C . PHE A 1 51 ? 69.590 9.168 134.906 1.00 2.01 ? 131 PHE N C 1 ATOM 404 O O . PHE A 1 51 ? 70.217 8.131 135.081 1.00 3.73 ? 131 PHE N O 1 ATOM 405 C CB . PHE A 1 51 ? 71.080 10.899 133.803 1.00 4.42 ? 131 PHE N CB 1 ATOM 406 C CG . PHE A 1 51 ? 71.528 12.355 133.736 1.00 3.87 ? 131 PHE N CG 1 ATOM 407 C CD1 . PHE A 1 51 ? 71.434 13.177 134.840 1.00 3.11 ? 131 PHE N CD1 1 ATOM 408 C CD2 . PHE A 1 51 ? 71.961 12.873 132.536 1.00 5.09 ? 131 PHE N CD2 1 ATOM 409 C CE1 . PHE A 1 51 ? 71.787 14.507 134.715 1.00 2.80 ? 131 PHE N CE1 1 ATOM 410 C CE2 . PHE A 1 51 ? 72.287 14.213 132.448 1.00 6.22 ? 131 PHE N CE2 1 ATOM 411 C CZ . PHE A 1 51 ? 72.207 15.040 133.534 1.00 2.80 ? 131 PHE N CZ 1 ATOM 412 N N . TYR A 1 52 ? 68.271 9.183 134.780 1.00 3.18 ? 132 TYR N N 1 ATOM 413 C CA . TYR A 1 52 ? 67.431 8.001 134.651 1.00 2.09 ? 132 TYR N CA 1 ATOM 414 C C . TYR A 1 52 ? 66.754 8.229 133.334 1.00 3.32 ? 132 TYR N C 1 ATOM 415 O O . TYR A 1 52 ? 66.635 9.387 132.937 1.00 2.90 ? 132 TYR N O 1 ATOM 416 C CB . TYR A 1 52 ? 66.339 7.929 135.708 1.00 2.47 ? 132 TYR N CB 1 ATOM 417 C CG . TYR A 1 52 ? 66.823 7.592 137.087 1.00 2.14 ? 132 TYR N CG 1 ATOM 418 C CD1 . TYR A 1 52 ? 67.578 8.495 137.784 1.00 2.00 ? 132 TYR N CD1 1 ATOM 419 C CD2 . TYR A 1 52 ? 66.552 6.343 137.548 1.00 2.00 ? 132 TYR N CD2 1 ATOM 420 C CE1 . TYR A 1 52 ? 68.113 8.157 138.982 1.00 3.01 ? 132 TYR N CE1 1 ATOM 421 C CE2 . TYR A 1 52 ? 67.085 5.999 138.753 1.00 2.23 ? 132 TYR N CE2 1 ATOM 422 C CZ . TYR A 1 52 ? 67.866 6.900 139.451 1.00 4.93 ? 132 TYR N CZ 1 ATOM 423 O OH . TYR A 1 52 ? 68.472 6.521 140.635 1.00 7.22 ? 132 TYR N OH 1 ATOM 424 N N . ALA A 1 53 ? 66.239 7.202 132.676 1.00 2.00 ? 133 ALA N N 1 ATOM 425 C CA . ALA A 1 53 ? 65.620 7.403 131.376 1.00 2.00 ? 133 ALA N CA 1 ATOM 426 C C . ALA A 1 53 ? 65.160 6.055 130.924 1.00 3.09 ? 133 ALA N C 1 ATOM 427 O O . ALA A 1 53 ? 65.773 5.095 131.394 1.00 7.99 ? 133 ALA N O 1 ATOM 428 C CB . ALA A 1 53 ? 66.594 7.867 130.340 1.00 2.00 ? 133 ALA N CB 1 ATOM 429 N N . LEU A 1 54 ? 64.161 5.941 130.054 1.00 3.98 ? 134 LEU N N 1 ATOM 430 C CA . LEU A 1 54 ? 63.657 4.678 129.526 1.00 3.41 ? 134 LEU N CA 1 ATOM 431 C C . LEU A 1 54 ? 64.458 4.242 128.290 1.00 6.08 ? 134 LEU N C 1 ATOM 432 O O . LEU A 1 54 ? 64.322 4.866 127.230 1.00 10.96 ? 134 LEU N O 1 ATOM 433 C CB . LEU A 1 54 ? 62.210 4.877 129.154 1.00 2.15 ? 134 LEU N CB 1 ATOM 434 C CG . LEU A 1 54 ? 61.086 4.226 129.930 1.00 3.21 ? 134 LEU N CG 1 ATOM 435 C CD1 . LEU A 1 54 ? 61.398 4.010 131.371 1.00 2.59 ? 134 LEU N CD1 1 ATOM 436 C CD2 . LEU A 1 54 ? 59.908 5.167 129.876 1.00 3.64 ? 134 LEU N CD2 1 ATOM 437 N N . SER A 1 55 ? 65.329 3.230 128.402 1.00 2.19 ? 135 SER N N 1 ATOM 438 C CA . SER A 1 55 ? 66.105 2.639 127.317 1.00 4.08 ? 135 SER N CA 1 ATOM 439 C C . SER A 1 55 ? 65.147 2.127 126.234 1.00 2.94 ? 135 SER N C 1 ATOM 440 O O . SER A 1 55 ? 63.993 1.821 126.522 1.00 6.96 ? 135 SER N O 1 ATOM 441 C CB . SER A 1 55 ? 66.958 1.434 127.883 1.00 4.46 ? 135 SER N CB 1 ATOM 442 O OG . SER A 1 55 ? 67.834 0.651 127.029 1.00 5.28 ? 135 SER N OG 1 ATOM 443 N N . GLN A 1 56 ? 65.597 2.054 124.982 1.00 4.18 ? 136 GLN N N 1 ATOM 444 C CA . GLN A 1 56 ? 64.887 1.341 123.920 1.00 4.00 ? 136 GLN N CA 1 ATOM 445 C C . GLN A 1 56 ? 65.526 0.007 123.506 1.00 3.48 ? 136 GLN N C 1 ATOM 446 O O . GLN A 1 56 ? 65.020 -0.660 122.606 1.00 3.91 ? 136 GLN N O 1 ATOM 447 C CB . GLN A 1 56 ? 64.776 2.189 122.684 1.00 3.37 ? 136 GLN N CB 1 ATOM 448 C CG . GLN A 1 56 ? 63.697 3.199 122.943 1.00 5.01 ? 136 GLN N CG 1 ATOM 449 C CD . GLN A 1 56 ? 62.294 2.964 122.409 1.00 4.75 ? 136 GLN N CD 1 ATOM 450 O OE1 . GLN A 1 56 ? 61.644 3.930 122.069 1.00 6.39 ? 136 GLN N OE1 1 ATOM 451 N NE2 . GLN A 1 56 ? 61.715 1.790 122.235 1.00 5.84 ? 136 GLN N NE2 1 ATOM 452 N N . GLY A 1 57 ? 66.638 -0.383 124.115 1.00 3.33 ? 137 GLY N N 1 ATOM 453 C CA . GLY A 1 57 ? 67.246 -1.669 123.847 1.00 2.80 ? 137 GLY N CA 1 ATOM 454 C C . GLY A 1 57 ? 68.055 -1.781 122.566 1.00 5.22 ? 137 GLY N C 1 ATOM 455 O O . GLY A 1 57 ? 68.056 -2.805 121.858 1.00 6.70 ? 137 GLY N O 1 ATOM 456 N N . THR A 1 58 ? 68.806 -0.716 122.298 1.00 5.73 ? 138 THR N N 1 ATOM 457 C CA . THR A 1 58 ? 69.570 -0.651 121.075 1.00 10.07 ? 138 THR N CA 1 ATOM 458 C C . THR A 1 58 ? 70.550 0.497 121.148 1.00 8.85 ? 138 THR N C 1 ATOM 459 O O . THR A 1 58 ? 70.428 1.309 122.051 1.00 9.61 ? 138 THR N O 1 ATOM 460 C CB . THR A 1 58 ? 68.549 -0.509 119.928 1.00 11.25 ? 138 THR N CB 1 ATOM 461 O OG1 . THR A 1 58 ? 69.311 -0.389 118.762 1.00 14.79 ? 138 THR N OG1 1 ATOM 462 C CG2 . THR A 1 58 ? 67.594 0.639 120.109 1.00 13.24 ? 138 THR N CG2 1 ATOM 463 N N . THR A 1 59 ? 71.553 0.607 120.281 1.00 6.39 ? 139 THR N N 1 ATOM 464 C CA . THR A 1 59 ? 72.390 1.791 120.289 1.00 5.59 ? 139 THR N CA 1 ATOM 465 C C . THR A 1 59 ? 71.896 2.667 119.139 1.00 6.20 ? 139 THR N C 1 ATOM 466 O O . THR A 1 59 ? 71.316 2.139 118.198 1.00 6.55 ? 139 THR N O 1 ATOM 467 C CB . THR A 1 59 ? 73.887 1.411 120.099 1.00 4.01 ? 139 THR N CB 1 ATOM 468 O OG1 . THR A 1 59 ? 74.073 0.727 118.855 1.00 2.06 ? 139 THR N OG1 1 ATOM 469 C CG2 . THR A 1 59 ? 74.337 0.516 121.262 1.00 4.00 ? 139 THR N CG2 1 ATOM 470 N N . ILE A 1 60 ? 72.089 3.993 119.199 1.00 6.03 ? 140 ILE N N 1 ATOM 471 C CA . ILE A 1 60 ? 71.656 4.979 118.199 1.00 6.29 ? 140 ILE N CA 1 ATOM 472 C C . ILE A 1 60 ? 72.020 4.415 116.849 1.00 5.78 ? 140 ILE N C 1 ATOM 473 O O . ILE A 1 60 ? 71.202 4.344 115.928 1.00 7.28 ? 140 ILE N O 1 ATOM 474 C CB . ILE A 1 60 ? 72.391 6.392 118.252 1.00 6.13 ? 140 ILE N CB 1 ATOM 475 C CG1 . ILE A 1 60 ? 72.661 6.918 119.633 1.00 5.56 ? 140 ILE N CG1 1 ATOM 476 C CG2 . ILE A 1 60 ? 71.519 7.361 117.474 1.00 2.63 ? 140 ILE N CG2 1 ATOM 477 C CD1 . ILE A 1 60 ? 71.342 7.386 120.261 1.00 9.15 ? 140 ILE N CD1 1 ATOM 478 N N . ARG A 1 61 ? 73.311 4.086 116.779 1.00 4.00 ? 141 ARG N N 1 ATOM 479 C CA . ARG A 1 61 ? 73.903 3.544 115.577 1.00 2.92 ? 141 ARG N CA 1 ATOM 480 C C . ARG A 1 61 ? 73.460 2.135 115.253 1.00 2.68 ? 141 ARG N C 1 ATOM 481 O O . ARG A 1 61 ? 73.375 1.841 114.073 1.00 4.19 ? 141 ARG N O 1 ATOM 482 C CB . ARG A 1 61 ? 75.404 3.597 115.723 1.00 3.48 ? 141 ARG N CB 1 ATOM 483 C CG . ARG A 1 61 ? 76.152 4.472 114.750 1.00 4.38 ? 141 ARG N CG 1 ATOM 484 C CD . ARG A 1 61 ? 75.686 5.926 114.762 1.00 7.35 ? 141 ARG N CD 1 ATOM 485 N NE . ARG A 1 61 ? 76.554 6.786 113.949 1.00 9.28 ? 141 ARG N NE 1 ATOM 486 C CZ . ARG A 1 61 ? 76.387 6.991 112.628 1.00 10.01 ? 141 ARG N CZ 1 ATOM 487 N NH1 . ARG A 1 61 ? 75.402 6.409 111.933 1.00 12.91 ? 141 ARG N NH1 1 ATOM 488 N NH2 . ARG A 1 61 ? 77.214 7.781 111.950 1.00 9.87 ? 141 ARG N NH2 1 ATOM 489 N N . GLY A 1 62 ? 73.139 1.230 116.175 1.00 2.00 ? 142 GLY N N 1 ATOM 490 C CA . GLY A 1 62 ? 72.772 -0.112 115.747 1.00 2.91 ? 142 GLY N CA 1 ATOM 491 C C . GLY A 1 62 ? 71.514 -0.199 114.874 1.00 3.53 ? 142 GLY N C 1 ATOM 492 O O . GLY A 1 62 ? 70.501 0.455 115.115 1.00 2.34 ? 142 GLY N O 1 ATOM 493 N N . LYS A 1 63 ? 71.419 -1.094 113.908 1.00 7.02 ? 143 LYS N N 1 ATOM 494 C CA . LYS A 1 63 ? 70.269 -1.163 113.039 1.00 10.45 ? 143 LYS N CA 1 ATOM 495 C C . LYS A 1 63 ? 68.927 -1.420 113.741 1.00 7.54 ? 143 LYS N C 1 ATOM 496 O O . LYS A 1 63 ? 67.883 -1.436 113.095 1.00 9.55 ? 143 LYS N O 1 ATOM 497 C CB . LYS A 1 63 ? 70.579 -2.237 112.013 1.00 11.68 ? 143 LYS N CB 1 ATOM 498 C CG . LYS A 1 63 ? 71.754 -1.941 111.088 1.00 15.78 ? 143 LYS N CG 1 ATOM 499 C CD . LYS A 1 63 ? 71.483 -2.656 109.780 1.00 20.37 ? 143 LYS N CD 1 ATOM 500 C CE . LYS A 1 63 ? 72.791 -3.188 109.228 1.00 24.27 ? 143 LYS N CE 1 ATOM 501 N NZ . LYS A 1 63 ? 73.151 -4.479 109.792 1.00 27.42 ? 143 LYS N NZ 1 ATOM 502 N N . HIS A 1 64 ? 68.856 -1.607 115.048 1.00 7.02 ? 144 HIS N N 1 ATOM 503 C CA . HIS A 1 64 ? 67.604 -1.894 115.741 1.00 7.09 ? 144 HIS N CA 1 ATOM 504 C C . HIS A 1 64 ? 67.094 -0.624 116.398 1.00 8.40 ? 144 HIS N C 1 ATOM 505 O O . HIS A 1 64 ? 66.123 -0.594 117.151 1.00 6.49 ? 144 HIS N O 1 ATOM 506 C CB . HIS A 1 64 ? 67.787 -2.919 116.832 1.00 3.53 ? 144 HIS N CB 1 ATOM 507 C CG . HIS A 1 64 ? 68.078 -4.320 116.380 1.00 2.81 ? 144 HIS N CG 1 ATOM 508 N ND1 . HIS A 1 64 ? 67.254 -5.212 115.876 1.00 2.60 ? 144 HIS N ND1 1 ATOM 509 C CD2 . HIS A 1 64 ? 69.303 -4.906 116.449 1.00 4.15 ? 144 HIS N CD2 1 ATOM 510 C CE1 . HIS A 1 64 ? 67.926 -6.308 115.655 1.00 2.23 ? 144 HIS N CE1 1 ATOM 511 N NE2 . HIS A 1 64 ? 69.154 -6.117 116.009 1.00 3.33 ? 144 HIS N NE2 1 ATOM 512 N N . SER A 1 65 ? 67.759 0.488 116.161 1.00 8.49 ? 145 SER N N 1 ATOM 513 C CA . SER A 1 65 ? 67.271 1.750 116.623 1.00 8.00 ? 145 SER N CA 1 ATOM 514 C C . SER A 1 65 ? 66.145 2.136 115.719 1.00 10.85 ? 145 SER N C 1 ATOM 515 O O . SER A 1 65 ? 65.486 3.114 116.062 1.00 13.06 ? 145 SER N O 1 ATOM 516 C CB . SER A 1 65 ? 68.385 2.729 116.521 1.00 7.45 ? 145 SER N CB 1 ATOM 517 O OG . SER A 1 65 ? 68.902 2.678 115.178 1.00 9.45 ? 145 SER N OG 1 ATOM 518 N N . ASN A 1 66 ? 65.925 1.487 114.555 1.00 10.76 ? 146 ASN N N 1 ATOM 519 C CA . ASN A 1 66 ? 64.872 1.897 113.620 1.00 15.26 ? 146 ASN N CA 1 ATOM 520 C C . ASN A 1 66 ? 63.426 1.679 114.010 1.00 14.85 ? 146 ASN N C 1 ATOM 521 O O . ASN A 1 66 ? 62.888 0.585 113.893 1.00 15.01 ? 146 ASN N O 1 ATOM 522 C CB . ASN A 1 66 ? 65.125 1.210 112.308 1.00 23.41 ? 146 ASN N CB 1 ATOM 523 C CG . ASN A 1 66 ? 64.094 1.337 111.190 1.00 30.01 ? 146 ASN N CG 1 ATOM 524 O OD1 . ASN A 1 66 ? 63.386 2.309 110.947 1.00 32.99 ? 146 ASN N OD1 1 ATOM 525 N ND2 . ASN A 1 66 ? 64.080 0.226 110.476 1.00 35.95 ? 146 ASN N ND2 1 ATOM 526 N N . GLY A 1 67 ? 62.807 2.734 114.505 1.00 13.74 ? 147 GLY N N 1 ATOM 527 C CA . GLY A 1 67 ? 61.410 2.702 114.816 1.00 11.91 ? 147 GLY N CA 1 ATOM 528 C C . GLY A 1 67 ? 61.238 2.848 116.297 1.00 11.54 ? 147 GLY N C 1 ATOM 529 O O . GLY A 1 67 ? 60.330 2.332 116.940 1.00 13.46 ? 147 GLY N O 1 ATOM 530 N N . THR A 1 68 ? 62.093 3.649 116.862 1.00 11.18 ? 148 THR N N 1 ATOM 531 C CA . THR A 1 68 ? 62.102 3.909 118.283 1.00 11.04 ? 148 THR N CA 1 ATOM 532 C C . THR A 1 68 ? 61.249 5.136 118.636 1.00 12.02 ? 148 THR N C 1 ATOM 533 O O . THR A 1 68 ? 61.222 5.722 119.726 1.00 14.40 ? 148 THR N O 1 ATOM 534 C CB . THR A 1 68 ? 63.561 4.031 118.610 1.00 8.16 ? 148 THR N CB 1 ATOM 535 O OG1 . THR A 1 68 ? 64.145 4.716 117.518 1.00 9.27 ? 148 THR N OG1 1 ATOM 536 C CG2 . THR A 1 68 ? 64.217 2.709 118.858 1.00 8.10 ? 148 THR N CG2 1 ATOM 537 N N . ILE A 1 69 ? 60.496 5.573 117.642 1.00 12.28 ? 149 ILE N N 1 ATOM 538 C CA . ILE A 1 69 ? 59.500 6.579 117.901 1.00 13.77 ? 149 ILE N CA 1 ATOM 539 C C . ILE A 1 69 ? 58.364 5.923 118.715 1.00 13.32 ? 149 ILE N C 1 ATOM 540 O O . ILE A 1 69 ? 57.662 6.615 119.456 1.00 12.88 ? 149 ILE N O 1 ATOM 541 C CB . ILE A 1 69 ? 59.060 7.116 116.538 1.00 13.95 ? 149 ILE N CB 1 ATOM 542 C CG1 . ILE A 1 69 ? 58.608 8.539 116.790 1.00 12.43 ? 149 ILE N CG1 1 ATOM 543 C CG2 . ILE A 1 69 ? 58.066 6.171 115.840 1.00 15.63 ? 149 ILE N CG2 1 ATOM 544 C CD1 . ILE A 1 69 ? 57.852 9.142 115.623 1.00 13.22 ? 149 ILE N CD1 1 ATOM 545 N N . HIS A 1 70 ? 58.136 4.601 118.596 1.00 14.18 ? 150 HIS N N 1 ATOM 546 C CA . HIS A 1 70 ? 57.112 3.931 119.369 1.00 14.44 ? 150 HIS N CA 1 ATOM 547 C C . HIS A 1 70 ? 57.599 3.882 120.804 1.00 13.80 ? 150 HIS N C 1 ATOM 548 O O . HIS A 1 70 ? 58.674 3.375 121.121 1.00 14.64 ? 150 HIS N O 1 ATOM 549 C CB . HIS A 1 70 ? 56.880 2.513 118.912 1.00 18.74 ? 150 HIS N CB 1 ATOM 550 C CG . HIS A 1 70 ? 56.480 2.479 117.453 1.00 23.61 ? 150 HIS N CG 1 ATOM 551 N ND1 . HIS A 1 70 ? 57.211 2.034 116.431 1.00 25.66 ? 150 HIS N ND1 1 ATOM 552 C CD2 . HIS A 1 70 ? 55.297 2.946 116.954 1.00 25.73 ? 150 HIS N CD2 1 ATOM 553 C CE1 . HIS A 1 70 ? 56.528 2.203 115.332 1.00 27.00 ? 150 HIS N CE1 1 ATOM 554 N NE2 . HIS A 1 70 ? 55.382 2.750 115.667 1.00 27.71 ? 150 HIS N NE2 1 ATOM 555 N N . ASP A 1 71 ? 56.667 4.412 121.604 1.00 11.95 ? 151 ASP N N 1 ATOM 556 C CA . ASP A 1 71 ? 56.751 4.574 123.046 1.00 8.68 ? 151 ASP N CA 1 ATOM 557 C C . ASP A 1 71 ? 56.832 3.358 123.920 1.00 5.19 ? 151 ASP N C 1 ATOM 558 O O . ASP A 1 71 ? 57.376 3.439 125.021 1.00 3.57 ? 151 ASP N O 1 ATOM 559 C CB . ASP A 1 71 ? 55.556 5.339 123.592 1.00 11.39 ? 151 ASP N CB 1 ATOM 560 C CG . ASP A 1 71 ? 55.164 6.572 122.802 1.00 14.71 ? 151 ASP N CG 1 ATOM 561 O OD1 . ASP A 1 71 ? 55.932 7.534 122.807 1.00 17.71 ? 151 ASP N OD1 1 ATOM 562 O OD2 . ASP A 1 71 ? 54.104 6.535 122.174 1.00 15.37 ? 151 ASP N OD2 1 ATOM 563 N N . ARG A 1 72 ? 56.155 2.297 123.546 1.00 2.88 ? 152 ARG N N 1 ATOM 564 C CA . ARG A 1 72 ? 56.169 1.188 124.437 1.00 4.95 ? 152 ARG N CA 1 ATOM 565 C C . ARG A 1 72 ? 56.371 -0.150 123.769 1.00 5.76 ? 152 ARG N C 1 ATOM 566 O O . ARG A 1 72 ? 55.869 -0.344 122.670 1.00 5.80 ? 152 ARG N O 1 ATOM 567 C CB . ARG A 1 72 ? 54.875 1.317 125.189 1.00 6.61 ? 152 ARG N CB 1 ATOM 568 C CG . ARG A 1 72 ? 53.529 1.130 124.521 1.00 10.83 ? 152 ARG N CG 1 ATOM 569 C CD . ARG A 1 72 ? 52.565 1.459 125.630 1.00 13.10 ? 152 ARG N CD 1 ATOM 570 N NE . ARG A 1 72 ? 52.446 2.901 125.652 1.00 12.56 ? 152 ARG N NE 1 ATOM 571 C CZ . ARG A 1 72 ? 51.603 3.506 124.796 1.00 15.89 ? 152 ARG N CZ 1 ATOM 572 N NH1 . ARG A 1 72 ? 50.717 2.786 124.071 1.00 16.15 ? 152 ARG N NH1 1 ATOM 573 N NH2 . ARG A 1 72 ? 51.600 4.845 124.726 1.00 18.07 ? 152 ARG N NH2 1 ATOM 574 N N . SER A 1 73 ? 57.075 -1.118 124.355 1.00 3.90 ? 153 SER N N 1 ATOM 575 C CA . SER A 1 73 ? 57.416 -2.376 123.671 1.00 2.00 ? 153 SER N CA 1 ATOM 576 C C . SER A 1 73 ? 58.056 -3.250 124.708 1.00 2.53 ? 153 SER N C 1 ATOM 577 O O . SER A 1 73 ? 58.266 -2.771 125.852 1.00 2.16 ? 153 SER N O 1 ATOM 578 C CB . SER A 1 73 ? 58.447 -2.195 122.561 1.00 3.18 ? 153 SER N CB 1 ATOM 579 O OG . SER A 1 73 ? 59.800 -2.036 123.008 1.00 6.40 ? 153 SER N OG 1 ATOM 580 N N . GLN A 1 74 ? 58.517 -4.461 124.349 1.00 2.00 ? 154 GLN N N 1 ATOM 581 C CA . GLN A 1 74 ? 59.160 -5.190 125.425 1.00 4.47 ? 154 GLN N CA 1 ATOM 582 C C . GLN A 1 74 ? 60.655 -4.997 125.393 1.00 3.74 ? 154 GLN N C 1 ATOM 583 O O . GLN A 1 74 ? 61.369 -5.875 125.889 1.00 2.19 ? 154 GLN N O 1 ATOM 584 C CB . GLN A 1 74 ? 58.909 -6.666 125.376 1.00 4.81 ? 154 GLN N CB 1 ATOM 585 C CG . GLN A 1 74 ? 58.593 -7.268 124.080 1.00 5.79 ? 154 GLN N CG 1 ATOM 586 C CD . GLN A 1 74 ? 57.099 -7.314 123.956 1.00 5.75 ? 154 GLN N CD 1 ATOM 587 O OE1 . GLN A 1 74 ? 56.503 -6.895 122.965 1.00 7.75 ? 154 GLN N OE1 1 ATOM 588 N NE2 . GLN A 1 74 ? 56.514 -7.825 125.018 1.00 4.62 ? 154 GLN N NE2 1 ATOM 589 N N . TYR A 1 75 ? 61.151 -3.887 124.828 1.00 4.12 ? 155 TYR N N 1 ATOM 590 C CA . TYR A 1 75 ? 62.583 -3.698 124.749 1.00 4.04 ? 155 TYR N CA 1 ATOM 591 C C . TYR A 1 75 ? 63.056 -2.492 125.525 1.00 5.55 ? 155 TYR N C 1 ATOM 592 O O . TYR A 1 75 ? 64.242 -2.195 125.723 1.00 6.24 ? 155 TYR N O 1 ATOM 593 C CB . TYR A 1 75 ? 62.957 -3.592 123.306 1.00 2.39 ? 155 TYR N CB 1 ATOM 594 C CG . TYR A 1 75 ? 62.514 -4.840 122.540 1.00 4.78 ? 155 TYR N CG 1 ATOM 595 C CD1 . TYR A 1 75 ? 62.890 -6.105 122.985 1.00 6.30 ? 155 TYR N CD1 1 ATOM 596 C CD2 . TYR A 1 75 ? 61.658 -4.720 121.453 1.00 2.36 ? 155 TYR N CD2 1 ATOM 597 C CE1 . TYR A 1 75 ? 62.399 -7.242 122.369 1.00 3.69 ? 155 TYR N CE1 1 ATOM 598 C CE2 . TYR A 1 75 ? 61.171 -5.857 120.839 1.00 2.00 ? 155 TYR N CE2 1 ATOM 599 C CZ . TYR A 1 75 ? 61.554 -7.094 121.303 1.00 4.70 ? 155 TYR N CZ 1 ATOM 600 O OH . TYR A 1 75 ? 61.080 -8.194 120.653 1.00 7.48 ? 155 TYR N OH 1 ATOM 601 N N . ARG A 1 76 ? 62.031 -1.848 126.048 1.00 6.38 ? 156 ARG N N 1 ATOM 602 C CA . ARG A 1 76 ? 62.181 -0.654 126.856 1.00 4.20 ? 156 ARG N CA 1 ATOM 603 C C . ARG A 1 76 ? 62.505 -1.151 128.268 1.00 4.55 ? 156 ARG N C 1 ATOM 604 O O . ARG A 1 76 ? 62.205 -2.317 128.642 1.00 4.94 ? 156 ARG N O 1 ATOM 605 C CB . ARG A 1 76 ? 60.865 0.099 126.832 1.00 3.54 ? 156 ARG N CB 1 ATOM 606 C CG . ARG A 1 76 ? 60.329 0.783 125.585 1.00 3.94 ? 156 ARG N CG 1 ATOM 607 C CD . ARG A 1 76 ? 60.922 2.124 125.778 1.00 3.34 ? 156 ARG N CD 1 ATOM 608 N NE . ARG A 1 76 ? 60.143 3.196 125.271 1.00 2.93 ? 156 ARG N NE 1 ATOM 609 C CZ . ARG A 1 76 ? 60.600 4.453 125.344 1.00 4.95 ? 156 ARG N CZ 1 ATOM 610 N NH1 . ARG A 1 76 ? 61.809 4.776 125.833 1.00 6.20 ? 156 ARG N NH1 1 ATOM 611 N NH2 . ARG A 1 76 ? 59.813 5.445 124.887 1.00 5.56 ? 156 ARG N NH2 1 ATOM 612 N N . ALA A 1 77 ? 63.115 -0.276 129.063 1.00 6.12 ? 157 ALA N N 1 ATOM 613 C CA . ALA A 1 77 ? 63.512 -0.627 130.427 1.00 2.46 ? 157 ALA N CA 1 ATOM 614 C C . ALA A 1 77 ? 64.027 0.581 131.208 1.00 2.00 ? 157 ALA N C 1 ATOM 615 O O . ALA A 1 77 ? 64.880 1.280 130.671 1.00 3.29 ? 157 ALA N O 1 ATOM 616 C CB . ALA A 1 77 ? 64.624 -1.716 130.379 1.00 4.62 ? 157 ALA N CB 1 ATOM 617 N N . LEU A 1 78 ? 63.597 0.915 132.404 1.00 2.00 ? 158 LEU N N 1 ATOM 618 C CA . LEU A 1 78 ? 64.157 2.056 133.105 1.00 2.00 ? 158 LEU N CA 1 ATOM 619 C C . LEU A 1 78 ? 65.651 1.853 133.418 1.00 3.35 ? 158 LEU N C 1 ATOM 620 O O . LEU A 1 78 ? 65.988 0.951 134.182 1.00 2.38 ? 158 LEU N O 1 ATOM 621 C CB . LEU A 1 78 ? 63.364 2.266 134.391 1.00 2.00 ? 158 LEU N CB 1 ATOM 622 C CG . LEU A 1 78 ? 63.866 3.291 135.347 1.00 2.00 ? 158 LEU N CG 1 ATOM 623 C CD1 . LEU A 1 78 ? 63.828 4.635 134.656 1.00 2.00 ? 158 LEU N CD1 1 ATOM 624 C CD2 . LEU A 1 78 ? 63.123 3.153 136.641 1.00 2.00 ? 158 LEU N CD2 1 ATOM 625 N N . ILE A 1 79 ? 66.583 2.637 132.880 1.00 3.18 ? 159 ILE N N 1 ATOM 626 C CA . ILE A 1 79 ? 68.014 2.500 133.091 1.00 3.03 ? 159 ILE N CA 1 ATOM 627 C C . ILE A 1 79 ? 68.508 3.760 133.783 1.00 2.00 ? 159 ILE N C 1 ATOM 628 O O . ILE A 1 79 ? 67.787 4.756 133.828 1.00 3.61 ? 159 ILE N O 1 ATOM 629 C CB . ILE A 1 79 ? 68.815 2.342 131.767 1.00 3.25 ? 159 ILE N CB 1 ATOM 630 C CG1 . ILE A 1 79 ? 68.520 3.476 130.804 1.00 2.77 ? 159 ILE N CG1 1 ATOM 631 C CG2 . ILE A 1 79 ? 68.512 0.968 131.189 1.00 2.53 ? 159 ILE N CG2 1 ATOM 632 C CD1 . ILE A 1 79 ? 69.685 3.523 129.841 1.00 5.61 ? 159 ILE N CD1 1 ATOM 633 N N . SER A 1 80 ? 69.749 3.760 134.253 1.00 2.51 ? 160 SER N N 1 ATOM 634 C CA . SER A 1 80 ? 70.285 4.814 135.089 1.00 3.79 ? 160 SER N CA 1 ATOM 635 C C . SER A 1 80 ? 71.805 4.873 134.941 1.00 4.22 ? 160 SER N C 1 ATOM 636 O O . SER A 1 80 ? 72.434 3.835 134.673 1.00 4.13 ? 160 SER N O 1 ATOM 637 C CB . SER A 1 80 ? 69.784 4.438 136.497 1.00 6.51 ? 160 SER N CB 1 ATOM 638 O OG . SER A 1 80 ? 70.362 5.000 137.675 1.00 9.44 ? 160 SER N OG 1 ATOM 639 N N . TRP A 1 81 ? 72.440 6.038 135.091 1.00 3.04 ? 161 TRP N N 1 ATOM 640 C CA . TRP A 1 81 ? 73.872 6.229 134.869 1.00 2.00 ? 161 TRP N CA 1 ATOM 641 C C . TRP A 1 81 ? 74.362 7.549 135.441 1.00 2.06 ? 161 TRP N C 1 ATOM 642 O O . TRP A 1 81 ? 73.572 8.441 135.730 1.00 2.00 ? 161 TRP N O 1 ATOM 643 C CB . TRP A 1 81 ? 74.223 6.220 133.390 1.00 2.00 ? 161 TRP N CB 1 ATOM 644 C CG . TRP A 1 81 ? 73.612 7.353 132.618 1.00 4.04 ? 161 TRP N CG 1 ATOM 645 C CD1 . TRP A 1 81 ? 74.347 8.453 132.343 1.00 3.12 ? 161 TRP N CD1 1 ATOM 646 C CD2 . TRP A 1 81 ? 72.347 7.432 132.087 1.00 4.02 ? 161 TRP N CD2 1 ATOM 647 N NE1 . TRP A 1 81 ? 73.580 9.238 131.636 1.00 2.00 ? 161 TRP N NE1 1 ATOM 648 C CE2 . TRP A 1 81 ? 72.386 8.673 131.453 1.00 2.00 ? 161 TRP N CE2 1 ATOM 649 C CE3 . TRP A 1 81 ? 71.209 6.655 132.056 1.00 2.91 ? 161 TRP N CE3 1 ATOM 650 C CZ2 . TRP A 1 81 ? 71.303 9.177 130.776 1.00 2.13 ? 161 TRP N CZ2 1 ATOM 651 C CZ3 . TRP A 1 81 ? 70.129 7.151 131.387 1.00 2.75 ? 161 TRP N CZ3 1 ATOM 652 C CH2 . TRP A 1 81 ? 70.167 8.389 130.753 1.00 2.94 ? 161 TRP N CH2 1 ATOM 653 N N . PRO A 1 82 ? 75.655 7.715 135.652 1.00 2.71 ? 162 PRO N N 1 ATOM 654 C CA . PRO A 1 82 ? 76.287 8.871 136.207 1.00 2.00 ? 162 PRO N CA 1 ATOM 655 C C . PRO A 1 82 ? 75.862 10.248 135.756 1.00 2.00 ? 162 PRO N C 1 ATOM 656 O O . PRO A 1 82 ? 75.527 10.437 134.598 1.00 2.52 ? 162 PRO N O 1 ATOM 657 C CB . PRO A 1 82 ? 77.698 8.636 135.932 1.00 3.65 ? 162 PRO N CB 1 ATOM 658 C CG . PRO A 1 82 ? 77.857 7.169 136.155 1.00 2.48 ? 162 PRO N CG 1 ATOM 659 C CD . PRO A 1 82 ? 76.623 6.629 135.584 1.00 2.00 ? 162 PRO N CD 1 ATOM 660 N N . LEU A 1 83 ? 75.881 11.266 136.625 1.00 4.54 ? 163 LEU N N 1 ATOM 661 C CA . LEU A 1 83 ? 75.511 12.607 136.247 1.00 5.34 ? 163 LEU N CA 1 ATOM 662 C C . LEU A 1 83 ? 76.433 13.070 135.154 1.00 6.19 ? 163 LEU N C 1 ATOM 663 O O . LEU A 1 83 ? 77.646 12.940 135.267 1.00 8.69 ? 163 LEU N O 1 ATOM 664 C CB . LEU A 1 83 ? 75.605 13.523 137.470 1.00 3.09 ? 163 LEU N CB 1 ATOM 665 C CG . LEU A 1 83 ? 75.285 15.009 137.435 1.00 3.17 ? 163 LEU N CG 1 ATOM 666 C CD1 . LEU A 1 83 ? 73.804 15.269 137.509 1.00 4.23 ? 163 LEU N CD1 1 ATOM 667 C CD2 . LEU A 1 83 ? 76.087 15.628 138.576 1.00 2.00 ? 163 LEU N CD2 1 ATOM 668 N N . SER A 1 84 ? 75.743 13.431 134.064 1.00 5.61 ? 164 SER N N 1 ATOM 669 C CA . SER A 1 84 ? 76.259 13.976 132.810 1.00 4.89 ? 164 SER N CA 1 ATOM 670 C C . SER A 1 84 ? 77.103 13.103 131.887 1.00 6.78 ? 164 SER N C 1 ATOM 671 O O . SER A 1 84 ? 77.614 13.578 130.868 1.00 8.70 ? 164 SER N O 1 ATOM 672 C CB . SER A 1 84 ? 76.988 15.204 133.185 1.00 3.03 ? 164 SER N CB 1 ATOM 673 O OG . SER A 1 84 ? 76.066 15.933 133.958 1.00 2.00 ? 164 SER N OG 1 ATOM 674 N N . SER A 1 85 ? 77.261 11.820 132.200 1.00 7.00 ? 165 SER N N 1 ATOM 675 C CA . SER A 1 85 ? 77.899 10.912 131.253 1.00 6.63 ? 165 SER N CA 1 ATOM 676 C C . SER A 1 85 ? 76.765 10.489 130.297 1.00 2.90 ? 165 SER N C 1 ATOM 677 O O . SER A 1 85 ? 75.584 10.526 130.699 1.00 4.08 ? 165 SER N O 1 ATOM 678 C CB . SER A 1 85 ? 78.440 9.654 131.938 1.00 7.77 ? 165 SER N CB 1 ATOM 679 O OG . SER A 1 85 ? 79.455 9.992 132.851 1.00 10.86 ? 165 SER N OG 1 ATOM 680 N N . PRO A 1 86 ? 77.016 10.103 129.036 1.00 2.00 ? 166 PRO N N 1 ATOM 681 C CA . PRO A 1 86 ? 75.975 9.543 128.185 1.00 2.00 ? 166 PRO N CA 1 ATOM 682 C C . PRO A 1 86 ? 75.401 8.241 128.718 1.00 2.54 ? 166 PRO N C 1 ATOM 683 O O . PRO A 1 86 ? 76.054 7.657 129.574 1.00 5.81 ? 166 PRO N O 1 ATOM 684 C CB . PRO A 1 86 ? 76.651 9.443 126.823 1.00 2.00 ? 166 PRO N CB 1 ATOM 685 C CG . PRO A 1 86 ? 78.166 9.546 127.046 1.00 2.55 ? 166 PRO N CG 1 ATOM 686 C CD . PRO A 1 86 ? 78.261 10.388 128.321 1.00 3.89 ? 166 PRO N CD 1 ATOM 687 N N . PRO A 1 87 ? 74.227 7.717 128.357 1.00 2.00 ? 167 PRO N N 1 ATOM 688 C CA . PRO A 1 87 ? 73.696 6.433 128.804 1.00 2.00 ? 167 PRO N CA 1 ATOM 689 C C . PRO A 1 87 ? 74.293 5.272 127.999 1.00 3.00 ? 167 PRO N C 1 ATOM 690 O O . PRO A 1 87 ? 73.641 4.709 127.105 1.00 6.04 ? 167 PRO N O 1 ATOM 691 C CB . PRO A 1 87 ? 72.252 6.614 128.604 1.00 2.54 ? 167 PRO N CB 1 ATOM 692 C CG . PRO A 1 87 ? 72.181 7.394 127.361 1.00 2.00 ? 167 PRO N CG 1 ATOM 693 C CD . PRO A 1 87 ? 73.190 8.431 127.658 1.00 2.00 ? 167 PRO N CD 1 ATOM 694 N N . THR A 1 88 ? 75.546 4.961 128.254 1.00 5.23 ? 168 THR N N 1 ATOM 695 C CA . THR A 1 88 ? 76.326 3.992 127.518 1.00 11.04 ? 168 THR N CA 1 ATOM 696 C C . THR A 1 88 ? 75.950 2.548 127.781 1.00 7.97 ? 168 THR N C 1 ATOM 697 O O . THR A 1 88 ? 75.581 2.278 128.924 1.00 8.52 ? 168 THR N O 1 ATOM 698 C CB . THR A 1 88 ? 77.726 4.393 127.937 1.00 12.86 ? 168 THR N CB 1 ATOM 699 O OG1 . THR A 1 88 ? 78.177 5.296 126.941 1.00 17.69 ? 168 THR N OG1 1 ATOM 700 C CG2 . THR A 1 88 ? 78.581 3.227 128.239 1.00 18.37 ? 168 THR N CG2 1 ATOM 701 N N . VAL A 1 89 ? 76.134 1.590 126.855 1.00 6.22 ? 169 VAL N N 1 ATOM 702 C CA . VAL A 1 89 ? 75.828 0.168 127.084 1.00 8.40 ? 169 VAL N CA 1 ATOM 703 C C . VAL A 1 89 ? 76.541 -0.390 128.313 1.00 10.31 ? 169 VAL N C 1 ATOM 704 O O . VAL A 1 89 ? 75.965 -1.207 129.034 1.00 10.41 ? 169 VAL N O 1 ATOM 705 C CB . VAL A 1 89 ? 76.235 -0.705 125.895 1.00 3.59 ? 169 VAL N CB 1 ATOM 706 C CG1 . VAL A 1 89 ? 76.092 -2.159 126.157 1.00 5.36 ? 169 VAL N CG1 1 ATOM 707 C CG2 . VAL A 1 89 ? 75.257 -0.485 124.792 1.00 2.40 ? 169 VAL N CG2 1 ATOM 708 N N . TYR A 1 90 A 77.755 0.132 128.572 1.00 11.46 ? 169 TYR N N 1 ATOM 709 C CA . TYR A 1 90 A 78.706 -0.361 129.573 1.00 11.33 ? 169 TYR N CA 1 ATOM 710 C C . TYR A 1 90 A 78.632 0.404 130.887 1.00 15.44 ? 169 TYR N C 1 ATOM 711 O O . TYR A 1 90 A 79.432 0.163 131.799 1.00 17.28 ? 169 TYR N O 1 ATOM 712 C CB . TYR A 1 90 A 80.173 -0.278 128.996 1.00 6.59 ? 169 TYR N CB 1 ATOM 713 C CG . TYR A 1 90 A 80.275 -0.712 127.562 1.00 3.94 ? 169 TYR N CG 1 ATOM 714 C CD1 . TYR A 1 90 A 79.666 -1.856 127.208 1.00 2.84 ? 169 TYR N CD1 1 ATOM 715 C CD2 . TYR A 1 90 A 80.920 0.001 126.610 1.00 2.77 ? 169 TYR N CD2 1 ATOM 716 C CE1 . TYR A 1 90 A 79.680 -2.303 125.930 1.00 2.00 ? 169 TYR N CE1 1 ATOM 717 C CE2 . TYR A 1 90 A 80.951 -0.432 125.298 1.00 3.03 ? 169 TYR N CE2 1 ATOM 718 C CZ . TYR A 1 90 A 80.320 -1.595 124.974 1.00 2.00 ? 169 TYR N CZ 1 ATOM 719 O OH . TYR A 1 90 A 80.282 -2.108 123.703 1.00 5.14 ? 169 TYR N OH 1 ATOM 720 N N . ASN A 1 91 ? 77.739 1.389 131.020 1.00 18.45 ? 170 ASN N N 1 ATOM 721 C CA . ASN A 1 91 ? 77.701 2.065 132.286 1.00 20.58 ? 170 ASN N CA 1 ATOM 722 C C . ASN A 1 91 ? 76.249 2.314 132.640 1.00 18.34 ? 170 ASN N C 1 ATOM 723 O O . ASN A 1 91 ? 75.953 3.202 133.432 1.00 17.36 ? 170 ASN N O 1 ATOM 724 C CB . ASN A 1 91 ? 78.545 3.345 132.141 1.00 24.09 ? 170 ASN N CB 1 ATOM 725 C CG . ASN A 1 91 ? 77.964 4.500 131.337 1.00 28.47 ? 170 ASN N CG 1 ATOM 726 O OD1 . ASN A 1 91 ? 78.649 5.487 131.095 1.00 32.51 ? 170 ASN N OD1 1 ATOM 727 N ND2 . ASN A 1 91 ? 76.765 4.563 130.777 1.00 29.33 ? 170 ASN N ND2 1 ATOM 728 N N . SER A 1 92 ? 75.294 1.590 132.064 1.00 14.65 ? 171 SER N N 1 ATOM 729 C CA . SER A 1 92 ? 73.932 1.795 132.481 1.00 13.65 ? 171 SER N CA 1 ATOM 730 C C . SER A 1 92 ? 73.529 0.689 133.412 1.00 12.88 ? 171 SER N C 1 ATOM 731 O O . SER A 1 92 ? 73.983 -0.447 133.318 1.00 14.94 ? 171 SER N O 1 ATOM 732 C CB . SER A 1 92 ? 72.992 1.811 131.305 1.00 12.45 ? 171 SER N CB 1 ATOM 733 O OG . SER A 1 92 ? 73.297 2.849 130.369 1.00 14.68 ? 171 SER N OG 1 ATOM 734 N N . ARG A 1 93 ? 72.815 1.062 134.447 1.00 13.21 ? 172 ARG N N 1 ATOM 735 C CA . ARG A 1 93 ? 72.262 0.085 135.362 1.00 11.09 ? 172 ARG N CA 1 ATOM 736 C C . ARG A 1 93 ? 70.785 0.004 135.015 1.00 9.44 ? 172 ARG N C 1 ATOM 737 O O . ARG A 1 93 ? 70.129 1.043 134.858 1.00 9.94 ? 172 ARG N O 1 ATOM 738 C CB . ARG A 1 93 ? 72.428 0.536 136.783 1.00 12.91 ? 172 ARG N CB 1 ATOM 739 C CG . ARG A 1 93 ? 72.004 -0.483 137.788 1.00 16.82 ? 172 ARG N CG 1 ATOM 740 C CD . ARG A 1 93 ? 71.661 0.220 139.082 1.00 22.19 ? 172 ARG N CD 1 ATOM 741 N NE . ARG A 1 93 ? 72.805 0.868 139.716 1.00 24.29 ? 172 ARG N NE 1 ATOM 742 C CZ . ARG A 1 93 ? 72.727 2.060 140.312 1.00 24.72 ? 172 ARG N CZ 1 ATOM 743 N NH1 . ARG A 1 93 ? 71.652 2.846 140.220 1.00 25.55 ? 172 ARG N NH1 1 ATOM 744 N NH2 . ARG A 1 93 ? 73.810 2.530 140.905 1.00 24.73 ? 172 ARG N NH2 1 ATOM 745 N N . VAL A 1 94 ? 70.291 -1.215 134.807 1.00 8.10 ? 173 VAL N N 1 ATOM 746 C CA . VAL A 1 94 ? 68.889 -1.483 134.617 1.00 5.49 ? 173 VAL N CA 1 ATOM 747 C C . VAL A 1 94 ? 68.267 -1.563 135.999 1.00 5.07 ? 173 VAL N C 1 ATOM 748 O O . VAL A 1 94 ? 68.680 -2.339 136.853 1.00 6.73 ? 173 VAL N O 1 ATOM 749 C CB . VAL A 1 94 ? 68.669 -2.810 133.867 1.00 4.62 ? 173 VAL N CB 1 ATOM 750 C CG1 . VAL A 1 94 ? 67.167 -3.069 133.694 1.00 4.14 ? 173 VAL N CG1 1 ATOM 751 C CG2 . VAL A 1 94 ? 69.281 -2.738 132.501 1.00 4.82 ? 173 VAL N CG2 1 ATOM 752 N N . GLU A 1 95 ? 67.310 -0.655 136.147 1.00 6.08 ? 174 GLU N N 1 ATOM 753 C CA . GLU A 1 95 ? 66.522 -0.525 137.337 1.00 8.05 ? 174 GLU N CA 1 ATOM 754 C C . GLU A 1 95 ? 65.315 -1.441 137.299 1.00 6.30 ? 174 GLU N C 1 ATOM 755 O O . GLU A 1 95 ? 64.975 -2.043 138.318 1.00 8.82 ? 174 GLU N O 1 ATOM 756 C CB . GLU A 1 95 ? 66.095 0.904 137.476 1.00 7.92 ? 174 GLU N CB 1 ATOM 757 C CG . GLU A 1 95 ? 67.263 1.889 137.584 1.00 9.74 ? 174 GLU N CG 1 ATOM 758 C CD . GLU A 1 95 ? 67.956 2.021 138.928 1.00 11.53 ? 174 GLU N CD 1 ATOM 759 O OE1 . GLU A 1 95 ? 67.444 1.467 139.910 1.00 14.18 ? 174 GLU N OE1 1 ATOM 760 O OE2 . GLU A 1 95 ? 69.001 2.684 138.970 1.00 12.98 ? 174 GLU N OE2 1 ATOM 761 N N . CYS A 1 96 ? 64.595 -1.633 136.219 1.00 5.41 ? 175 CYS N N 1 ATOM 762 C CA . CYS A 1 96 ? 63.513 -2.624 136.150 1.00 3.60 ? 175 CYS N CA 1 ATOM 763 C C . CYS A 1 96 ? 63.039 -2.652 134.721 1.00 3.86 ? 175 CYS N C 1 ATOM 764 O O . CYS A 1 96 ? 63.531 -1.872 133.880 1.00 3.27 ? 175 CYS N O 1 ATOM 765 C CB . CYS A 1 96 ? 62.312 -2.298 137.049 1.00 6.87 ? 175 CYS N CB 1 ATOM 766 S SG . CYS A 1 96 ? 61.702 -0.596 137.174 1.00 3.79 ? 175 CYS N SG 1 ATOM 767 N N . ILE A 1 97 ? 62.176 -3.583 134.368 1.00 2.32 ? 176 ILE N N 1 ATOM 768 C CA . ILE A 1 97 ? 61.694 -3.618 132.990 1.00 3.16 ? 176 ILE N CA 1 ATOM 769 C C . ILE A 1 97 ? 60.271 -3.012 132.761 1.00 2.90 ? 176 ILE N C 1 ATOM 770 O O . ILE A 1 97 ? 59.314 -3.331 133.445 1.00 2.00 ? 176 ILE N O 1 ATOM 771 C CB . ILE A 1 97 ? 61.844 -5.101 132.602 1.00 2.00 ? 176 ILE N CB 1 ATOM 772 C CG1 . ILE A 1 97 ? 63.312 -5.478 132.807 1.00 2.00 ? 176 ILE N CG1 1 ATOM 773 C CG2 . ILE A 1 97 ? 61.451 -5.340 131.203 1.00 2.00 ? 176 ILE N CG2 1 ATOM 774 C CD1 . ILE A 1 97 ? 64.376 -4.835 131.889 1.00 3.30 ? 176 ILE N CD1 1 ATOM 775 N N . GLY A 1 98 ? 60.095 -2.026 131.880 1.00 2.00 ? 177 GLY N N 1 ATOM 776 C CA . GLY A 1 98 ? 58.817 -1.466 131.544 1.00 2.00 ? 177 GLY N CA 1 ATOM 777 C C . GLY A 1 98 ? 58.938 -0.205 130.696 1.00 2.00 ? 177 GLY N C 1 ATOM 778 O O . GLY A 1 98 ? 60.014 0.361 130.522 1.00 3.14 ? 177 GLY N O 1 ATOM 779 N N . TRP A 1 99 ? 57.785 0.276 130.259 1.00 2.00 ? 178 TRP N N 1 ATOM 780 C CA . TRP A 1 99 ? 57.665 1.483 129.477 1.00 2.00 ? 178 TRP N CA 1 ATOM 781 C C . TRP A 1 99 ? 57.021 2.680 130.183 1.00 3.91 ? 178 TRP N C 1 ATOM 782 O O . TRP A 1 99 ? 56.646 3.675 129.559 1.00 4.39 ? 178 TRP N O 1 ATOM 783 C CB . TRP A 1 99 ? 56.928 1.156 128.231 1.00 2.00 ? 178 TRP N CB 1 ATOM 784 C CG . TRP A 1 99 ? 55.695 0.264 128.323 1.00 3.23 ? 178 TRP N CG 1 ATOM 785 C CD1 . TRP A 1 99 ? 55.724 -1.052 127.905 1.00 2.46 ? 178 TRP N CD1 1 ATOM 786 C CD2 . TRP A 1 99 ? 54.475 0.634 128.797 1.00 2.08 ? 178 TRP N CD2 1 ATOM 787 N NE1 . TRP A 1 99 ? 54.523 -1.509 128.117 1.00 2.39 ? 178 TRP N NE1 1 ATOM 788 C CE2 . TRP A 1 99 ? 53.745 -0.546 128.644 1.00 4.45 ? 178 TRP N CE2 1 ATOM 789 C CE3 . TRP A 1 99 ? 53.898 1.749 129.338 1.00 3.00 ? 178 TRP N CE3 1 ATOM 790 C CZ2 . TRP A 1 99 ? 52.407 -0.641 129.031 1.00 3.61 ? 178 TRP N CZ2 1 ATOM 791 C CZ3 . TRP A 1 99 ? 52.574 1.667 129.718 1.00 3.03 ? 178 TRP N CZ3 1 ATOM 792 C CH2 . TRP A 1 99 ? 51.825 0.495 129.570 1.00 5.24 ? 178 TRP N CH2 1 ATOM 793 N N . SER A 1 100 ? 56.813 2.651 131.512 1.00 3.41 ? 179 SER N N 1 ATOM 794 C CA . SER A 1 100 ? 56.500 3.880 132.242 1.00 2.72 ? 179 SER N CA 1 ATOM 795 C C . SER A 1 100 ? 57.167 3.730 133.581 1.00 2.00 ? 179 SER N C 1 ATOM 796 O O . SER A 1 100 ? 57.123 2.651 134.162 1.00 2.00 ? 179 SER N O 1 ATOM 797 C CB . SER A 1 100 ? 55.015 4.059 132.455 1.00 3.18 ? 179 SER N CB 1 ATOM 798 O OG . SER A 1 100 ? 54.749 5.451 132.558 1.00 2.94 ? 179 SER N OG 1 ATOM 799 N N . SER A 1 101 ? 57.825 4.760 134.063 1.00 2.29 ? 180 SER N N 1 ATOM 800 C CA . SER A 1 101 ? 58.526 4.685 135.316 1.00 3.16 ? 180 SER N CA 1 ATOM 801 C C . SER A 1 101 ? 58.359 5.954 136.137 1.00 3.06 ? 180 SER N C 1 ATOM 802 O O . SER A 1 101 ? 57.835 7.019 135.778 1.00 2.78 ? 180 SER N O 1 ATOM 803 C CB . SER A 1 101 ? 60.000 4.448 135.041 1.00 3.89 ? 180 SER N CB 1 ATOM 804 O OG . SER A 1 101 ? 60.698 5.626 134.609 1.00 4.02 ? 180 SER N OG 1 ATOM 805 N N . THR A 1 102 ? 58.924 5.779 137.303 1.00 3.42 ? 181 THR N N 1 ATOM 806 C CA . THR A 1 102 ? 59.028 6.766 138.326 1.00 2.00 ? 181 THR N CA 1 ATOM 807 C C . THR A 1 102 ? 60.018 6.119 139.307 1.00 2.66 ? 181 THR N C 1 ATOM 808 O O . THR A 1 102 ? 60.067 4.887 139.437 1.00 3.48 ? 181 THR N O 1 ATOM 809 C CB . THR A 1 102 ? 57.625 6.965 138.834 1.00 2.00 ? 181 THR N CB 1 ATOM 810 O OG1 . THR A 1 102 ? 57.682 8.087 139.689 1.00 2.00 ? 181 THR N OG1 1 ATOM 811 C CG2 . THR A 1 102 ? 57.067 5.740 139.487 1.00 2.00 ? 181 THR N CG2 1 ATOM 812 N N . SER A 1 103 ? 60.844 6.905 139.964 1.00 2.23 ? 182 SER N N 1 ATOM 813 C CA . SER A 1 103 ? 61.810 6.331 140.856 1.00 2.04 ? 182 SER N CA 1 ATOM 814 C C . SER A 1 103 ? 62.079 7.313 141.962 1.00 3.74 ? 182 SER N C 1 ATOM 815 O O . SER A 1 103 ? 62.312 8.478 141.671 1.00 2.20 ? 182 SER N O 1 ATOM 816 C CB . SER A 1 103 ? 63.063 6.084 140.075 1.00 3.77 ? 182 SER N CB 1 ATOM 817 O OG . SER A 1 103 ? 64.071 5.320 140.713 1.00 5.26 ? 182 SER N OG 1 ATOM 818 N N . CYS A 1 104 ? 62.034 6.987 143.235 1.00 3.75 ? 183 CYS N N 1 ATOM 819 C CA . CYS A 1 104 ? 62.534 7.898 144.275 1.00 3.87 ? 183 CYS N CA 1 ATOM 820 C C . CYS A 1 104 ? 63.140 7.241 145.487 1.00 2.00 ? 183 CYS N C 1 ATOM 821 O O . CYS A 1 104 ? 62.960 6.042 145.715 1.00 2.00 ? 183 CYS N O 1 ATOM 822 C CB . CYS A 1 104 ? 61.473 8.851 144.793 1.00 6.46 ? 183 CYS N CB 1 ATOM 823 S SG . CYS A 1 104 ? 59.940 8.110 145.309 1.00 2.00 ? 183 CYS N SG 1 ATOM 824 N N . HIS A 1 105 ? 63.927 7.985 146.241 1.00 2.00 ? 184 HIS N N 1 ATOM 825 C CA . HIS A 1 105 ? 64.677 7.391 147.334 1.00 2.16 ? 184 HIS N CA 1 ATOM 826 C C . HIS A 1 105 ? 64.205 7.927 148.652 1.00 2.89 ? 184 HIS N C 1 ATOM 827 O O . HIS A 1 105 ? 64.256 9.144 148.863 1.00 3.52 ? 184 HIS N O 1 ATOM 828 C CB . HIS A 1 105 ? 66.134 7.717 147.112 1.00 4.43 ? 184 HIS N CB 1 ATOM 829 C CG . HIS A 1 105 ? 67.134 7.041 148.033 1.00 2.70 ? 184 HIS N CG 1 ATOM 830 N ND1 . HIS A 1 105 ? 67.171 6.810 149.335 1.00 2.98 ? 184 HIS N ND1 1 ATOM 831 C CD2 . HIS A 1 105 ? 68.316 6.605 147.544 1.00 2.00 ? 184 HIS N CD2 1 ATOM 832 C CE1 . HIS A 1 105 ? 68.315 6.264 149.657 1.00 2.00 ? 184 HIS N CE1 1 ATOM 833 N NE2 . HIS A 1 105 ? 68.989 6.151 148.560 1.00 2.00 ? 184 HIS N NE2 1 ATOM 834 N N . ASP A 1 106 ? 63.881 7.062 149.597 1.00 7.26 ? 185 ASP N N 1 ATOM 835 C CA . ASP A 1 106 ? 63.244 7.601 150.754 1.00 9.83 ? 185 ASP N CA 1 ATOM 836 C C . ASP A 1 106 ? 64.110 8.011 151.924 1.00 10.23 ? 185 ASP N C 1 ATOM 837 O O . ASP A 1 106 ? 63.621 8.333 153.016 1.00 12.96 ? 185 ASP N O 1 ATOM 838 C CB . ASP A 1 106 ? 62.166 6.609 151.179 1.00 9.14 ? 185 ASP N CB 1 ATOM 839 C CG . ASP A 1 106 ? 62.454 5.126 151.451 1.00 10.55 ? 185 ASP N CG 1 ATOM 840 O OD1 . ASP A 1 106 ? 63.586 4.759 151.820 1.00 10.31 ? 185 ASP N OD1 1 ATOM 841 O OD2 . ASP A 1 106 ? 61.483 4.362 151.312 1.00 11.98 ? 185 ASP N OD2 1 ATOM 842 N N . GLY A 1 107 ? 65.398 8.138 151.706 1.00 11.21 ? 186 GLY N N 1 ATOM 843 C CA . GLY A 1 107 ? 66.273 8.407 152.817 1.00 14.40 ? 186 GLY N CA 1 ATOM 844 C C . GLY A 1 107 ? 66.995 7.116 153.114 1.00 15.37 ? 186 GLY N C 1 ATOM 845 O O . GLY A 1 107 ? 68.210 7.110 153.305 1.00 17.30 ? 186 GLY N O 1 ATOM 846 N N . LYS A 1 108 ? 66.273 6.013 153.156 1.00 16.37 ? 187 LYS N N 1 ATOM 847 C CA . LYS A 1 108 ? 66.923 4.752 153.400 1.00 17.88 ? 187 LYS N CA 1 ATOM 848 C C . LYS A 1 108 ? 67.347 4.076 152.118 1.00 15.46 ? 187 LYS N C 1 ATOM 849 O O . LYS A 1 108 ? 68.531 3.824 151.971 1.00 17.45 ? 187 LYS N O 1 ATOM 850 C CB . LYS A 1 108 ? 65.998 3.881 154.194 1.00 21.10 ? 187 LYS N CB 1 ATOM 851 C CG . LYS A 1 108 ? 66.282 4.067 155.682 1.00 25.83 ? 187 LYS N CG 1 ATOM 852 C CD . LYS A 1 108 ? 64.953 4.127 156.402 1.00 30.05 ? 187 LYS N CD 1 ATOM 853 C CE . LYS A 1 108 ? 64.968 3.894 157.905 1.00 33.51 ? 187 LYS N CE 1 ATOM 854 N NZ . LYS A 1 108 ? 64.892 2.484 158.256 1.00 38.10 ? 187 LYS N NZ 1 ATOM 855 N N . THR A 1 109 ? 66.487 3.781 151.139 1.00 13.45 ? 188 THR N N 1 ATOM 856 C CA . THR A 1 109 ? 66.893 3.157 149.881 1.00 9.66 ? 188 THR N CA 1 ATOM 857 C C . THR A 1 109 ? 65.892 3.595 148.827 1.00 8.20 ? 188 THR N C 1 ATOM 858 O O . THR A 1 109 ? 65.056 4.475 149.132 1.00 9.73 ? 188 THR N O 1 ATOM 859 C CB . THR A 1 109 ? 66.929 1.617 150.082 1.00 6.84 ? 188 THR N CB 1 ATOM 860 O OG1 . THR A 1 109 ? 67.655 1.159 148.972 1.00 7.50 ? 188 THR N OG1 1 ATOM 861 C CG2 . THR A 1 109 ? 65.640 0.869 150.041 1.00 4.98 ? 188 THR N CG2 1 ATOM 862 N N . ARG A 1 110 ? 65.964 3.077 147.588 1.00 4.73 ? 189 ARG N N 1 ATOM 863 C CA . ARG A 1 110 ? 64.967 3.521 146.634 1.00 4.27 ? 189 ARG N CA 1 ATOM 864 C C . ARG A 1 110 ? 63.980 2.552 145.965 1.00 4.11 ? 189 ARG N C 1 ATOM 865 O O . ARG A 1 110 ? 64.066 1.304 145.921 1.00 2.00 ? 189 ARG N O 1 ATOM 866 C CB . ARG A 1 110 ? 65.651 4.334 145.551 1.00 5.11 ? 189 ARG N CB 1 ATOM 867 C CG . ARG A 1 110 ? 66.541 3.758 144.521 1.00 5.91 ? 189 ARG N CG 1 ATOM 868 C CD . ARG A 1 110 ? 66.373 4.711 143.367 1.00 3.41 ? 189 ARG N CD 1 ATOM 869 N NE . ARG A 1 110 ? 67.132 5.954 143.559 1.00 5.64 ? 189 ARG N NE 1 ATOM 870 C CZ . ARG A 1 110 ? 66.608 7.166 143.241 1.00 8.42 ? 189 ARG N CZ 1 ATOM 871 N NH1 . ARG A 1 110 ? 65.380 7.258 142.738 1.00 11.67 ? 189 ARG N NH1 1 ATOM 872 N NH2 . ARG A 1 110 ? 67.284 8.317 143.421 1.00 9.61 ? 189 ARG N NH2 1 ATOM 873 N N . MET A 1 111 ? 62.888 3.273 145.731 1.00 5.56 ? 190 MET N N 1 ATOM 874 C CA . MET A 1 111 ? 61.728 2.740 145.101 1.00 3.93 ? 190 MET N CA 1 ATOM 875 C C . MET A 1 111 ? 61.779 3.041 143.609 1.00 5.43 ? 190 MET N C 1 ATOM 876 O O . MET A 1 111 ? 62.007 4.175 143.169 1.00 8.85 ? 190 MET N O 1 ATOM 877 C CB . MET A 1 111 ? 60.529 3.359 145.742 1.00 2.00 ? 190 MET N CB 1 ATOM 878 C CG . MET A 1 111 ? 59.401 2.588 145.101 1.00 3.70 ? 190 MET N CG 1 ATOM 879 S SD . MET A 1 111 ? 57.725 2.800 145.716 1.00 7.34 ? 190 MET N SD 1 ATOM 880 C CE . MET A 1 111 ? 57.463 4.555 145.472 1.00 4.65 ? 190 MET N CE 1 ATOM 881 N N . SER A 1 112 ? 61.590 2.024 142.787 1.00 4.78 ? 191 SER N N 1 ATOM 882 C CA . SER A 1 112 ? 61.471 2.178 141.346 1.00 5.42 ? 191 SER N CA 1 ATOM 883 C C . SER A 1 112 ? 60.271 1.300 140.978 1.00 4.54 ? 191 SER N C 1 ATOM 884 O O . SER A 1 112 ? 60.057 0.217 141.559 1.00 2.52 ? 191 SER N O 1 ATOM 885 C CB . SER A 1 112 ? 62.714 1.698 140.594 1.00 5.07 ? 191 SER N CB 1 ATOM 886 O OG . SER A 1 112 ? 63.856 2.464 140.934 1.00 6.18 ? 191 SER N OG 1 ATOM 887 N N . ILE A 1 113 ? 59.442 1.898 140.114 1.00 3.16 ? 192 ILE N N 1 ATOM 888 C CA . ILE A 1 113 ? 58.238 1.281 139.634 1.00 2.53 ? 192 ILE N CA 1 ATOM 889 C C . ILE A 1 113 ? 58.344 1.323 138.106 1.00 2.00 ? 192 ILE N C 1 ATOM 890 O O . ILE A 1 113 ? 58.456 2.407 137.520 1.00 2.00 ? 192 ILE N O 1 ATOM 891 C CB . ILE A 1 113 ? 57.084 2.145 140.243 1.00 6.01 ? 192 ILE N CB 1 ATOM 892 C CG1 . ILE A 1 113 ? 57.144 2.093 141.742 1.00 4.07 ? 192 ILE N CG1 1 ATOM 893 C CG2 . ILE A 1 113 ? 55.705 1.692 139.713 1.00 4.31 ? 192 ILE N CG2 1 ATOM 894 C CD1 . ILE A 1 113 ? 56.292 3.227 142.311 1.00 4.75 ? 192 ILE N CD1 1 ATOM 895 N N . CYS A 1 114 ? 58.365 0.193 137.420 1.00 4.00 ? 193 CYS N N 1 ATOM 896 C CA . CYS A 1 114 ? 58.300 0.131 135.957 1.00 6.48 ? 193 CYS N CA 1 ATOM 897 C C . CYS A 1 114 ? 56.966 -0.471 135.547 1.00 7.75 ? 193 CYS N C 1 ATOM 898 O O . CYS A 1 114 ? 56.634 -1.521 136.086 1.00 10.49 ? 193 CYS N O 1 ATOM 899 C CB . CYS A 1 114 ? 59.354 -0.761 135.337 1.00 6.82 ? 193 CYS N CB 1 ATOM 900 S SG . CYS A 1 114 ? 61.048 -0.149 135.326 1.00 6.82 ? 193 CYS N SG 1 ATOM 901 N N . ILE A 1 115 ? 56.153 0.080 134.651 1.00 7.91 ? 194 ILE N N 1 ATOM 902 C CA . ILE A 1 115 ? 54.856 -0.460 134.210 1.00 5.32 ? 194 ILE N CA 1 ATOM 903 C C . ILE A 1 115 ? 55.123 -1.126 132.858 1.00 6.34 ? 194 ILE N C 1 ATOM 904 O O . ILE A 1 115 ? 55.931 -0.648 132.062 1.00 4.26 ? 194 ILE N O 1 ATOM 905 C CB . ILE A 1 115 ? 53.834 0.686 134.057 1.00 4.04 ? 194 ILE N CB 1 ATOM 906 C CG1 . ILE A 1 115 ? 53.537 1.316 135.411 1.00 2.84 ? 194 ILE N CG1 1 ATOM 907 C CG2 . ILE A 1 115 ? 52.570 0.144 133.427 1.00 4.23 ? 194 ILE N CG2 1 ATOM 908 C CD1 . ILE A 1 115 ? 52.662 2.579 135.355 1.00 2.00 ? 194 ILE N CD1 1 ATOM 909 N N . SER A 1 116 ? 54.478 -2.236 132.607 1.00 8.28 ? 195 SER N N 1 ATOM 910 C CA . SER A 1 116 ? 54.726 -3.067 131.471 1.00 8.12 ? 195 SER N CA 1 ATOM 911 C C . SER A 1 116 ? 53.374 -3.624 131.087 1.00 10.00 ? 195 SER N C 1 ATOM 912 O O . SER A 1 116 ? 52.389 -3.542 131.827 1.00 12.23 ? 195 SER N O 1 ATOM 913 C CB . SER A 1 116 ? 55.603 -4.204 131.864 1.00 8.47 ? 195 SER N CB 1 ATOM 914 O OG . SER A 1 116 ? 55.837 -4.915 130.678 1.00 9.83 ? 195 SER N OG 1 ATOM 915 N N . GLY A 1 117 ? 53.393 -4.293 129.952 1.00 9.68 ? 196 GLY N N 1 ATOM 916 C CA . GLY A 1 117 ? 52.215 -4.909 129.453 1.00 9.20 ? 196 GLY N CA 1 ATOM 917 C C . GLY A 1 117 ? 51.724 -4.442 128.086 1.00 10.94 ? 196 GLY N C 1 ATOM 918 O O . GLY A 1 117 ? 52.131 -3.422 127.505 1.00 10.40 ? 196 GLY N O 1 ATOM 919 N N . PRO A 1 118 ? 50.804 -5.245 127.534 1.00 9.50 ? 197 PRO N N 1 ATOM 920 C CA . PRO A 1 118 ? 49.972 -4.814 126.447 1.00 10.46 ? 197 PRO N CA 1 ATOM 921 C C . PRO A 1 118 ? 49.100 -3.697 127.000 1.00 10.89 ? 197 PRO N C 1 ATOM 922 O O . PRO A 1 118 ? 48.826 -3.648 128.214 1.00 12.14 ? 197 PRO N O 1 ATOM 923 C CB . PRO A 1 118 ? 49.201 -6.021 126.080 1.00 9.53 ? 197 PRO N CB 1 ATOM 924 C CG . PRO A 1 118 ? 49.796 -7.161 126.840 1.00 11.06 ? 197 PRO N CG 1 ATOM 925 C CD . PRO A 1 118 ? 50.332 -6.515 128.072 1.00 8.14 ? 197 PRO N CD 1 ATOM 926 N N . ASN A 1 119 ? 48.608 -2.802 126.135 1.00 11.46 ? 198 ASN N N 1 ATOM 927 C CA . ASN A 1 119 ? 47.748 -1.721 126.571 1.00 11.83 ? 198 ASN N CA 1 ATOM 928 C C . ASN A 1 119 ? 46.511 -2.179 127.300 1.00 13.33 ? 198 ASN N C 1 ATOM 929 O O . ASN A 1 119 ? 46.191 -1.530 128.312 1.00 16.25 ? 198 ASN N O 1 ATOM 930 C CB . ASN A 1 119 ? 47.312 -0.862 125.420 1.00 13.46 ? 198 ASN N CB 1 ATOM 931 C CG . ASN A 1 119 ? 48.521 -0.262 124.731 1.00 16.26 ? 198 ASN N CG 1 ATOM 932 O OD1 . ASN A 1 119 ? 48.581 -0.298 123.514 1.00 16.16 ? 198 ASN N OD1 1 ATOM 933 N ND2 . ASN A 1 119 ? 49.603 0.229 125.336 1.00 19.68 ? 198 ASN N ND2 1 ATOM 934 N N . ASN A 1 120 ? 45.903 -3.324 126.974 1.00 13.53 ? 199 ASN N N 1 ATOM 935 C CA . ASN A 1 120 ? 44.681 -3.719 127.673 1.00 14.72 ? 199 ASN N CA 1 ATOM 936 C C . ASN A 1 120 ? 44.885 -4.635 128.867 1.00 16.27 ? 199 ASN N C 1 ATOM 937 O O . ASN A 1 120 ? 43.916 -5.124 129.446 1.00 19.04 ? 199 ASN N O 1 ATOM 938 C CB . ASN A 1 120 ? 43.705 -4.417 126.712 1.00 16.47 ? 199 ASN N CB 1 ATOM 939 C CG . ASN A 1 120 ? 44.060 -5.842 126.332 1.00 17.80 ? 199 ASN N CG 1 ATOM 940 O OD1 . ASN A 1 120 ? 45.189 -6.302 126.441 1.00 22.25 ? 199 ASN N OD1 1 ATOM 941 N ND2 . ASN A 1 120 ? 43.126 -6.604 125.815 1.00 19.81 ? 199 ASN N ND2 1 ATOM 942 N N . ASN A 1 121 ? 46.112 -4.891 129.297 1.00 15.04 ? 200 ASN N N 1 ATOM 943 C CA . ASN A 1 121 ? 46.307 -5.877 130.321 1.00 12.65 ? 200 ASN N CA 1 ATOM 944 C C . ASN A 1 121 ? 47.719 -5.591 130.837 1.00 12.21 ? 200 ASN N C 1 ATOM 945 O O . ASN A 1 121 ? 48.619 -6.433 130.799 1.00 13.46 ? 200 ASN N O 1 ATOM 946 C CB . ASN A 1 121 ? 46.128 -7.232 129.615 1.00 10.55 ? 200 ASN N CB 1 ATOM 947 C CG . ASN A 1 121 ? 45.736 -8.387 130.496 1.00 11.16 ? 200 ASN N CG 1 ATOM 948 O OD1 . ASN A 1 121 ? 45.233 -8.162 131.592 1.00 13.12 ? 200 ASN N OD1 1 ATOM 949 N ND2 . ASN A 1 121 ? 45.959 -9.667 130.141 1.00 12.17 ? 200 ASN N ND2 1 ATOM 950 N N . ALA A 1 122 ? 47.953 -4.393 131.361 1.00 11.36 ? 201 ALA N N 1 ATOM 951 C CA . ALA A 1 122 ? 49.262 -4.004 131.812 1.00 13.27 ? 201 ALA N CA 1 ATOM 952 C C . ALA A 1 122 ? 49.437 -4.228 133.318 1.00 13.78 ? 201 ALA N C 1 ATOM 953 O O . ALA A 1 122 ? 48.395 -4.454 133.931 1.00 15.33 ? 201 ALA N O 1 ATOM 954 C CB . ALA A 1 122 ? 49.436 -2.557 131.447 1.00 15.45 ? 201 ALA N CB 1 ATOM 955 N N . SER A 1 123 ? 50.649 -4.260 133.916 1.00 14.02 ? 202 SER N N 1 ATOM 956 C CA . SER A 1 123 ? 50.897 -4.345 135.350 1.00 12.45 ? 202 SER N CA 1 ATOM 957 C C . SER A 1 123 ? 52.031 -3.456 135.828 1.00 13.29 ? 202 SER N C 1 ATOM 958 O O . SER A 1 123 ? 53.033 -3.258 135.147 1.00 13.69 ? 202 SER N O 1 ATOM 959 C CB . SER A 1 123 ? 51.334 -5.686 135.786 1.00 11.72 ? 202 SER N CB 1 ATOM 960 O OG . SER A 1 123 ? 50.319 -6.580 135.420 1.00 14.44 ? 202 SER N OG 1 ATOM 961 N N . ALA A 1 124 ? 51.920 -2.883 136.997 1.00 11.60 ? 203 ALA N N 1 ATOM 962 C CA . ALA A 1 124 ? 52.956 -2.100 137.615 1.00 10.83 ? 203 ALA N CA 1 ATOM 963 C C . ALA A 1 124 ? 53.717 -3.000 138.587 1.00 11.12 ? 203 ALA N C 1 ATOM 964 O O . ALA A 1 124 ? 53.049 -3.797 139.258 1.00 11.81 ? 203 ALA N O 1 ATOM 965 C CB . ALA A 1 124 ? 52.322 -0.954 138.390 1.00 10.07 ? 203 ALA N CB 1 ATOM 966 N N . VAL A 1 125 ? 55.052 -2.980 138.677 1.00 9.79 ? 204 VAL N N 1 ATOM 967 C CA . VAL A 1 125 ? 55.713 -3.685 139.759 1.00 11.77 ? 204 VAL N CA 1 ATOM 968 C C . VAL A 1 125 ? 56.685 -2.691 140.392 1.00 9.54 ? 204 VAL N C 1 ATOM 969 O O . VAL A 1 125 ? 57.355 -1.823 139.831 1.00 8.64 ? 204 VAL N O 1 ATOM 970 C CB . VAL A 1 125 ? 56.363 -5.030 139.212 1.00 12.90 ? 204 VAL N CB 1 ATOM 971 C CG1 . VAL A 1 125 ? 56.860 -4.876 137.822 1.00 16.34 ? 204 VAL N CG1 1 ATOM 972 C CG2 . VAL A 1 125 ? 57.538 -5.446 140.065 1.00 14.89 ? 204 VAL N CG2 1 ATOM 973 N N . ILE A 1 126 ? 56.489 -2.726 141.686 1.00 7.80 ? 205 ILE N N 1 ATOM 974 C CA . ILE A 1 126 ? 57.155 -1.824 142.564 1.00 6.66 ? 205 ILE N CA 1 ATOM 975 C C . ILE A 1 126 ? 58.300 -2.581 143.167 1.00 5.12 ? 205 ILE N C 1 ATOM 976 O O . ILE A 1 126 ? 58.083 -3.499 143.950 1.00 2.70 ? 205 ILE N O 1 ATOM 977 C CB . ILE A 1 126 ? 56.139 -1.318 143.650 1.00 4.87 ? 205 ILE N CB 1 ATOM 978 C CG1 . ILE A 1 126 ? 55.090 -0.434 142.976 1.00 2.88 ? 205 ILE N CG1 1 ATOM 979 C CG2 . ILE A 1 126 ? 56.810 -0.480 144.720 1.00 2.91 ? 205 ILE N CG2 1 ATOM 980 C CD1 . ILE A 1 126 ? 53.852 -1.153 142.432 1.00 2.15 ? 205 ILE N CD1 1 ATOM 981 N N . TRP A 1 127 ? 59.490 -2.168 142.720 1.00 5.03 ? 206 TRP N N 1 ATOM 982 C CA . TRP A 1 127 ? 60.791 -2.583 143.204 1.00 3.87 ? 206 TRP N CA 1 ATOM 983 C C . TRP A 1 127 ? 61.206 -1.757 144.429 1.00 5.25 ? 206 TRP N C 1 ATOM 984 O O . TRP A 1 127 ? 61.007 -0.544 144.434 1.00 8.43 ? 206 TRP N O 1 ATOM 985 C CB . TRP A 1 127 ? 61.763 -2.414 142.062 1.00 2.00 ? 206 TRP N CB 1 ATOM 986 C CG . TRP A 1 127 ? 61.646 -3.465 140.956 1.00 2.35 ? 206 TRP N CG 1 ATOM 987 C CD1 . TRP A 1 127 ? 60.634 -3.474 140.034 1.00 4.84 ? 206 TRP N CD1 1 ATOM 988 C CD2 . TRP A 1 127 ? 62.509 -4.493 140.720 1.00 2.97 ? 206 TRP N CD2 1 ATOM 989 N NE1 . TRP A 1 127 ? 60.848 -4.481 139.221 1.00 2.23 ? 206 TRP N NE1 1 ATOM 990 C CE2 . TRP A 1 127 ? 61.950 -5.106 139.606 1.00 3.11 ? 206 TRP N CE2 1 ATOM 991 C CE3 . TRP A 1 127 ? 63.687 -4.980 141.288 1.00 3.96 ? 206 TRP N CE3 1 ATOM 992 C CZ2 . TRP A 1 127 ? 62.554 -6.204 139.054 1.00 2.38 ? 206 TRP N CZ2 1 ATOM 993 C CZ3 . TRP A 1 127 ? 64.289 -6.083 140.718 1.00 2.85 ? 206 TRP N CZ3 1 ATOM 994 C CH2 . TRP A 1 127 ? 63.721 -6.681 139.619 1.00 2.00 ? 206 TRP N CH2 1 ATOM 995 N N . TYR A 1 128 ? 61.720 -2.340 145.524 1.00 5.61 ? 207 TYR N N 1 ATOM 996 C CA . TYR A 1 128 ? 62.193 -1.585 146.686 1.00 8.61 ? 207 TYR N CA 1 ATOM 997 C C . TYR A 1 128 ? 63.481 -2.264 147.123 1.00 7.57 ? 207 TYR N C 1 ATOM 998 O O . TYR A 1 128 ? 63.492 -3.462 147.360 1.00 4.05 ? 207 TYR N O 1 ATOM 999 C CB . TYR A 1 128 ? 61.218 -1.600 147.896 1.00 8.57 ? 207 TYR N CB 1 ATOM 1000 C CG . TYR A 1 128 ? 61.672 -0.679 149.059 1.00 6.64 ? 207 TYR N CG 1 ATOM 1001 C CD1 . TYR A 1 128 ? 61.819 0.690 148.874 1.00 8.60 ? 207 TYR N CD1 1 ATOM 1002 C CD2 . TYR A 1 128 ? 61.965 -1.218 150.302 1.00 8.57 ? 207 TYR N CD2 1 ATOM 1003 C CE1 . TYR A 1 128 ? 62.247 1.513 149.896 1.00 11.24 ? 207 TYR N CE1 1 ATOM 1004 C CE2 . TYR A 1 128 ? 62.403 -0.392 151.337 1.00 9.84 ? 207 TYR N CE2 1 ATOM 1005 C CZ . TYR A 1 128 ? 62.548 0.975 151.134 1.00 10.93 ? 207 TYR N CZ 1 ATOM 1006 O OH . TYR A 1 128 ? 63.006 1.790 152.168 1.00 8.23 ? 207 TYR N OH 1 ATOM 1007 N N . ASN A 1 129 ? 64.577 -1.512 147.224 1.00 7.83 ? 208 ASN N N 1 ATOM 1008 C CA . ASN A 1 129 ? 65.909 -2.029 147.520 1.00 8.56 ? 208 ASN N CA 1 ATOM 1009 C C . ASN A 1 129 ? 66.243 -3.088 146.477 1.00 10.72 ? 208 ASN N C 1 ATOM 1010 O O . ASN A 1 129 ? 66.578 -4.231 146.752 1.00 9.94 ? 208 ASN N O 1 ATOM 1011 C CB . ASN A 1 129 ? 66.004 -2.668 148.922 1.00 8.18 ? 208 ASN N CB 1 ATOM 1012 C CG . ASN A 1 129 ? 67.454 -2.996 149.233 1.00 9.45 ? 208 ASN N CG 1 ATOM 1013 O OD1 . ASN A 1 129 ? 68.206 -2.175 149.743 1.00 10.71 ? 208 ASN N OD1 1 ATOM 1014 N ND2 . ASN A 1 129 ? 67.963 -4.167 148.920 1.00 9.58 ? 208 ASN N ND2 1 ATOM 1015 N N . ARG A 1 130 ? 66.028 -2.734 145.214 1.00 12.82 ? 209 ARG N N 1 ATOM 1016 C CA . ARG A 1 130 ? 66.337 -3.567 144.061 1.00 14.40 ? 209 ARG N CA 1 ATOM 1017 C C . ARG A 1 130 ? 65.701 -4.968 144.043 1.00 10.42 ? 209 ARG N C 1 ATOM 1018 O O . ARG A 1 130 ? 66.208 -5.908 143.433 1.00 10.01 ? 209 ARG N O 1 ATOM 1019 C CB . ARG A 1 130 ? 67.907 -3.646 143.919 1.00 21.21 ? 209 ARG N CB 1 ATOM 1020 C CG . ARG A 1 130 ? 68.612 -2.256 143.766 1.00 26.95 ? 209 ARG N CG 1 ATOM 1021 C CD . ARG A 1 130 ? 69.700 -1.942 142.671 1.00 33.75 ? 209 ARG N CD 1 ATOM 1022 N NE . ARG A 1 130 ? 69.245 -2.054 141.273 1.00 41.01 ? 209 ARG N NE 1 ATOM 1023 C CZ . ARG A 1 130 ? 69.615 -3.097 140.482 1.00 45.50 ? 209 ARG N CZ 1 ATOM 1024 N NH1 . ARG A 1 130 ? 70.561 -3.968 140.863 1.00 47.00 ? 209 ARG N NH1 1 ATOM 1025 N NH2 . ARG A 1 130 ? 69.137 -3.253 139.238 1.00 47.42 ? 209 ARG N NH2 1 ATOM 1026 N N . ARG A 1 131 ? 64.557 -5.179 144.676 1.00 10.82 ? 210 ARG N N 1 ATOM 1027 C CA . ARG A 1 131 ? 63.875 -6.460 144.614 1.00 5.18 ? 210 ARG N CA 1 ATOM 1028 C C . ARG A 1 131 ? 62.415 -6.133 144.419 1.00 5.07 ? 210 ARG N C 1 ATOM 1029 O O . ARG A 1 131 ? 61.963 -5.112 144.949 1.00 3.15 ? 210 ARG N O 1 ATOM 1030 C CB . ARG A 1 131 ? 63.994 -7.233 145.905 1.00 4.94 ? 210 ARG N CB 1 ATOM 1031 C CG . ARG A 1 131 ? 65.354 -7.791 146.290 1.00 5.50 ? 210 ARG N CG 1 ATOM 1032 C CD . ARG A 1 131 ? 65.570 -7.881 147.810 1.00 6.07 ? 210 ARG N CD 1 ATOM 1033 N NE . ARG A 1 131 ? 66.649 -8.813 147.947 1.00 6.36 ? 210 ARG N NE 1 ATOM 1034 C CZ . ARG A 1 131 ? 67.839 -8.588 148.517 1.00 6.87 ? 210 ARG N CZ 1 ATOM 1035 N NH1 . ARG A 1 131 ? 68.024 -7.663 149.471 1.00 6.33 ? 210 ARG N NH1 1 ATOM 1036 N NH2 . ARG A 1 131 ? 68.822 -9.494 148.278 1.00 10.00 ? 210 ARG N NH2 1 ATOM 1037 N N . PRO A 1 132 ? 61.636 -6.891 143.641 1.00 5.25 ? 211 PRO N N 1 ATOM 1038 C CA . PRO A 1 132 ? 60.229 -6.646 143.470 1.00 3.26 ? 211 PRO N CA 1 ATOM 1039 C C . PRO A 1 132 ? 59.503 -6.964 144.753 1.00 5.62 ? 211 PRO N C 1 ATOM 1040 O O . PRO A 1 132 ? 59.734 -8.006 145.374 1.00 6.72 ? 211 PRO N O 1 ATOM 1041 C CB . PRO A 1 132 ? 59.904 -7.502 142.298 1.00 3.09 ? 211 PRO N CB 1 ATOM 1042 C CG . PRO A 1 132 ? 60.828 -8.668 142.402 1.00 2.00 ? 211 PRO N CG 1 ATOM 1043 C CD . PRO A 1 132 ? 62.087 -7.958 142.763 1.00 3.83 ? 211 PRO N CD 1 ATOM 1044 N N . VAL A 1 133 ? 58.716 -6.013 145.231 1.00 8.62 ? 212 VAL N N 1 ATOM 1045 C CA . VAL A 1 133 ? 57.969 -6.175 146.450 1.00 7.32 ? 212 VAL N CA 1 ATOM 1046 C C . VAL A 1 133 ? 56.525 -6.275 146.074 1.00 8.52 ? 212 VAL N C 1 ATOM 1047 O O . VAL A 1 133 ? 56.007 -7.378 146.127 1.00 9.20 ? 212 VAL N O 1 ATOM 1048 C CB . VAL A 1 133 ? 58.199 -5.009 147.341 1.00 5.71 ? 212 VAL N CB 1 ATOM 1049 C CG1 . VAL A 1 133 ? 57.230 -4.994 148.487 1.00 8.84 ? 212 VAL N CG1 1 ATOM 1050 C CG2 . VAL A 1 133 ? 59.578 -5.135 147.909 1.00 6.66 ? 212 VAL N CG2 1 ATOM 1051 N N . THR A 1 134 ? 55.869 -5.187 145.651 1.00 11.38 ? 213 THR N N 1 ATOM 1052 C CA . THR A 1 134 ? 54.433 -5.113 145.337 1.00 12.26 ? 213 THR N CA 1 ATOM 1053 C C . THR A 1 134 ? 54.320 -5.042 143.825 1.00 12.64 ? 213 THR N C 1 ATOM 1054 O O . THR A 1 134 ? 55.323 -4.805 143.149 1.00 14.45 ? 213 THR N O 1 ATOM 1055 C CB . THR A 1 134 ? 53.889 -3.842 146.043 1.00 13.41 ? 213 THR N CB 1 ATOM 1056 O OG1 . THR A 1 134 ? 53.931 -4.244 147.385 1.00 16.78 ? 213 THR N OG1 1 ATOM 1057 C CG2 . THR A 1 134 ? 52.486 -3.383 145.763 1.00 13.68 ? 213 THR N CG2 1 ATOM 1058 N N . GLU A 1 135 ? 53.137 -5.336 143.270 1.00 13.09 ? 214 GLU N N 1 ATOM 1059 C CA . GLU A 1 135 ? 52.765 -5.242 141.854 1.00 12.47 ? 214 GLU N CA 1 ATOM 1060 C C . GLU A 1 135 ? 51.285 -4.871 141.858 1.00 9.53 ? 214 GLU N C 1 ATOM 1061 O O . GLU A 1 135 ? 50.618 -5.095 142.864 1.00 8.74 ? 214 GLU N O 1 ATOM 1062 C CB . GLU A 1 135 ? 52.925 -6.536 141.068 1.00 11.38 ? 214 GLU N CB 1 ATOM 1063 C CG . GLU A 1 135 ? 52.811 -7.801 141.838 1.00 12.98 ? 214 GLU N CG 1 ATOM 1064 C CD . GLU A 1 135 ? 53.975 -8.138 142.724 1.00 12.28 ? 214 GLU N CD 1 ATOM 1065 O OE1 . GLU A 1 135 ? 55.048 -7.570 142.598 1.00 12.59 ? 214 GLU N OE1 1 ATOM 1066 O OE2 . GLU A 1 135 ? 53.810 -9.003 143.554 1.00 14.65 ? 214 GLU N OE2 1 ATOM 1067 N N . ILE A 1 136 ? 50.746 -4.267 140.820 1.00 8.59 ? 215 ILE N N 1 ATOM 1068 C CA . ILE A 1 136 ? 49.425 -3.660 140.819 1.00 6.65 ? 215 ILE N CA 1 ATOM 1069 C C . ILE A 1 136 ? 49.033 -3.962 139.403 1.00 7.25 ? 215 ILE N C 1 ATOM 1070 O O . ILE A 1 136 ? 49.754 -3.515 138.530 1.00 8.69 ? 215 ILE N O 1 ATOM 1071 C CB . ILE A 1 136 ? 49.547 -2.113 141.070 1.00 4.29 ? 215 ILE N CB 1 ATOM 1072 C CG1 . ILE A 1 136 ? 49.683 -1.815 142.529 1.00 3.15 ? 215 ILE N CG1 1 ATOM 1073 C CG2 . ILE A 1 136 ? 48.317 -1.391 140.607 1.00 4.32 ? 215 ILE N CG2 1 ATOM 1074 C CD1 . ILE A 1 136 ? 50.021 -0.347 142.708 1.00 4.33 ? 215 ILE N CD1 1 ATOM 1075 N N . ASN A 1 137 ? 47.990 -4.734 139.124 1.00 5.17 ? 216 ASN N N 1 ATOM 1076 C CA . ASN A 1 137 ? 47.596 -5.051 137.765 1.00 4.61 ? 216 ASN N CA 1 ATOM 1077 C C . ASN A 1 137 ? 46.609 -3.971 137.290 1.00 5.61 ? 216 ASN N C 1 ATOM 1078 O O . ASN A 1 137 ? 46.169 -3.213 138.159 1.00 7.15 ? 216 ASN N O 1 ATOM 1079 C CB . ASN A 1 137 ? 46.997 -6.458 137.787 1.00 6.61 ? 216 ASN N CB 1 ATOM 1080 C CG . ASN A 1 137 ? 46.548 -6.902 136.401 1.00 6.82 ? 216 ASN N CG 1 ATOM 1081 O OD1 . ASN A 1 137 ? 45.346 -7.093 136.196 1.00 6.89 ? 216 ASN N OD1 1 ATOM 1082 N ND2 . ASN A 1 137 ? 47.385 -6.986 135.350 1.00 5.69 ? 216 ASN N ND2 1 ATOM 1083 N N . THR A 1 138 ? 46.235 -3.840 135.996 1.00 4.10 ? 217 THR N N 1 ATOM 1084 C CA . THR A 1 138 ? 45.529 -2.679 135.500 1.00 5.65 ? 217 THR N CA 1 ATOM 1085 C C . THR A 1 138 ? 44.149 -2.518 136.065 1.00 6.11 ? 217 THR N C 1 ATOM 1086 O O . THR A 1 138 ? 43.611 -3.497 136.570 1.00 6.44 ? 217 THR N O 1 ATOM 1087 C CB . THR A 1 138 ? 45.528 -2.773 133.949 1.00 4.53 ? 217 THR N CB 1 ATOM 1088 O OG1 . THR A 1 138 ? 44.766 -1.655 133.530 1.00 5.63 ? 217 THR N OG1 1 ATOM 1089 C CG2 . THR A 1 138 ? 44.869 -4.007 133.318 1.00 4.03 ? 217 THR N CG2 1 ATOM 1090 N N . TRP A 1 139 ? 43.572 -1.305 136.022 1.00 6.79 ? 218 TRP N N 1 ATOM 1091 C CA . TRP A 1 139 ? 42.205 -1.125 136.522 1.00 5.48 ? 218 TRP N CA 1 ATOM 1092 C C . TRP A 1 139 ? 41.130 -0.656 135.616 1.00 6.59 ? 218 TRP N C 1 ATOM 1093 O O . TRP A 1 139 ? 39.956 -0.812 135.883 1.00 5.89 ? 218 TRP N O 1 ATOM 1094 C CB . TRP A 1 139 ? 42.137 -0.189 137.688 1.00 3.98 ? 218 TRP N CB 1 ATOM 1095 C CG . TRP A 1 139 ? 42.882 1.118 137.610 1.00 4.93 ? 218 TRP N CG 1 ATOM 1096 C CD1 . TRP A 1 139 ? 42.292 2.190 137.040 1.00 4.45 ? 218 TRP N CD1 1 ATOM 1097 C CD2 . TRP A 1 139 ? 44.113 1.372 138.167 1.00 6.19 ? 218 TRP N CD2 1 ATOM 1098 N NE1 . TRP A 1 139 ? 43.143 3.142 137.264 1.00 8.61 ? 218 TRP N NE1 1 ATOM 1099 C CE2 . TRP A 1 139 ? 44.234 2.707 137.917 1.00 7.72 ? 218 TRP N CE2 1 ATOM 1100 C CE3 . TRP A 1 139 ? 45.126 0.717 138.844 1.00 4.94 ? 218 TRP N CE3 1 ATOM 1101 C CZ2 . TRP A 1 139 ? 45.333 3.434 138.308 1.00 4.02 ? 218 TRP N CZ2 1 ATOM 1102 C CZ3 . TRP A 1 139 ? 46.230 1.445 139.254 1.00 3.81 ? 218 TRP N CZ3 1 ATOM 1103 C CH2 . TRP A 1 139 ? 46.332 2.794 138.983 1.00 2.78 ? 218 TRP N CH2 1 ATOM 1104 N N . ALA A 1 140 ? 41.556 -0.047 134.552 1.00 7.76 ? 219 ALA N N 1 ATOM 1105 C CA . ALA A 1 140 ? 40.667 0.470 133.533 1.00 8.17 ? 219 ALA N CA 1 ATOM 1106 C C . ALA A 1 140 ? 41.049 -0.143 132.193 1.00 11.31 ? 219 ALA N C 1 ATOM 1107 O O . ALA A 1 140 ? 40.447 0.159 131.174 1.00 11.53 ? 219 ALA N O 1 ATOM 1108 C CB . ALA A 1 140 ? 40.811 1.962 133.397 1.00 9.60 ? 219 ALA N CB 1 ATOM 1109 N N . ARG A 1 141 ? 42.114 -0.941 132.153 1.00 14.49 ? 220 ARG N N 1 ATOM 1110 C CA . ARG A 1 141 ? 42.529 -1.676 130.983 1.00 16.80 ? 220 ARG N CA 1 ATOM 1111 C C . ARG A 1 141 ? 42.898 -0.926 129.711 1.00 14.52 ? 220 ARG N C 1 ATOM 1112 O O . ARG A 1 141 ? 42.881 -1.473 128.623 1.00 14.17 ? 220 ARG N O 1 ATOM 1113 C CB . ARG A 1 141 ? 41.428 -2.758 130.669 1.00 18.68 ? 220 ARG N CB 1 ATOM 1114 C CG . ARG A 1 141 ? 41.237 -3.778 131.778 1.00 22.06 ? 220 ARG N CG 1 ATOM 1115 C CD . ARG A 1 141 ? 40.551 -5.096 131.343 1.00 25.78 ? 220 ARG N CD 1 ATOM 1116 N NE . ARG A 1 141 ? 40.773 -6.104 132.405 1.00 30.20 ? 220 ARG N NE 1 ATOM 1117 C CZ . ARG A 1 141 ? 41.973 -6.696 132.613 1.00 32.47 ? 220 ARG N CZ 1 ATOM 1118 N NH1 . ARG A 1 141 ? 42.983 -6.518 131.748 1.00 33.89 ? 220 ARG N NH1 1 ATOM 1119 N NH2 . ARG A 1 141 ? 42.174 -7.505 133.665 1.00 33.21 ? 220 ARG N NH2 1 ATOM 1120 N N . ASN A 1 142 ? 43.283 0.310 129.734 1.00 15.74 ? 221 ASN N N 1 ATOM 1121 C CA . ASN A 1 142 ? 43.754 0.916 128.514 1.00 15.61 ? 221 ASN N CA 1 ATOM 1122 C C . ASN A 1 142 ? 44.835 1.799 129.064 1.00 14.62 ? 221 ASN N C 1 ATOM 1123 O O . ASN A 1 142 ? 44.549 2.728 129.830 1.00 15.61 ? 221 ASN N O 1 ATOM 1124 C CB . ASN A 1 142 ? 42.687 1.754 127.872 1.00 18.81 ? 221 ASN N CB 1 ATOM 1125 C CG . ASN A 1 142 ? 43.177 2.542 126.656 1.00 21.65 ? 221 ASN N CG 1 ATOM 1126 O OD1 . ASN A 1 142 ? 43.546 1.999 125.609 1.00 24.23 ? 221 ASN N OD1 1 ATOM 1127 N ND2 . ASN A 1 142 ? 43.258 3.865 126.728 1.00 21.74 ? 221 ASN N ND2 1 ATOM 1128 N N . ILE A 1 143 ? 46.053 1.328 128.786 1.00 9.76 ? 222 ILE N N 1 ATOM 1129 C CA . ILE A 1 143 ? 47.353 1.922 129.112 1.00 7.89 ? 222 ILE N CA 1 ATOM 1130 C C . ILE A 1 143 ? 47.497 2.624 130.464 1.00 7.43 ? 222 ILE N C 1 ATOM 1131 O O . ILE A 1 143 ? 47.208 3.818 130.605 1.00 9.65 ? 222 ILE N O 1 ATOM 1132 C CB . ILE A 1 143 ? 47.773 2.951 128.022 1.00 6.09 ? 222 ILE N CB 1 ATOM 1133 C CG1 . ILE A 1 143 ? 47.513 2.481 126.622 1.00 4.21 ? 222 ILE N CG1 1 ATOM 1134 C CG2 . ILE A 1 143 ? 49.266 3.170 128.181 1.00 5.05 ? 222 ILE N CG2 1 ATOM 1135 C CD1 . ILE A 1 143 ? 47.927 3.528 125.595 1.00 4.38 ? 222 ILE N CD1 1 ATOM 1136 N N . LEU A 1 144 ? 47.916 1.812 131.456 1.00 6.45 ? 223 LEU N N 1 ATOM 1137 C CA . LEU A 1 144 ? 48.230 2.269 132.809 1.00 4.24 ? 223 LEU N CA 1 ATOM 1138 C C . LEU A 1 144 ? 49.546 2.952 132.619 1.00 4.76 ? 223 LEU N C 1 ATOM 1139 O O . LEU A 1 144 ? 50.449 2.374 132.024 1.00 7.22 ? 223 LEU N O 1 ATOM 1140 C CB . LEU A 1 144 ? 48.403 1.092 133.799 1.00 3.66 ? 223 LEU N CB 1 ATOM 1141 C CG . LEU A 1 144 ? 49.004 1.253 135.242 1.00 4.51 ? 223 LEU N CG 1 ATOM 1142 C CD1 . LEU A 1 144 ? 48.197 2.268 136.057 1.00 2.00 ? 223 LEU N CD1 1 ATOM 1143 C CD2 . LEU A 1 144 ? 49.052 -0.113 135.944 1.00 2.00 ? 223 LEU N CD2 1 ATOM 1144 N N . ARG A 1 145 ? 49.611 4.173 133.114 1.00 4.17 ? 224 ARG N N 1 ATOM 1145 C CA . ARG A 1 145 ? 50.785 5.033 132.982 1.00 3.93 ? 224 ARG N CA 1 ATOM 1146 C C . ARG A 1 145 ? 51.229 5.660 134.328 1.00 3.40 ? 224 ARG N C 1 ATOM 1147 O O . ARG A 1 145 ? 50.475 5.561 135.295 1.00 2.00 ? 224 ARG N O 1 ATOM 1148 C CB . ARG A 1 145 ? 50.467 6.167 132.030 1.00 4.87 ? 224 ARG N CB 1 ATOM 1149 C CG . ARG A 1 145 ? 49.380 6.020 130.956 1.00 3.92 ? 224 ARG N CG 1 ATOM 1150 C CD . ARG A 1 145 ? 48.735 7.386 130.843 1.00 5.61 ? 224 ARG N CD 1 ATOM 1151 N NE . ARG A 1 145 ? 47.558 7.564 129.991 1.00 7.94 ? 224 ARG N NE 1 ATOM 1152 C CZ . ARG A 1 145 ? 46.284 7.329 130.377 1.00 8.72 ? 224 ARG N CZ 1 ATOM 1153 N NH1 . ARG A 1 145 ? 45.979 6.596 131.453 1.00 8.92 ? 224 ARG N NH1 1 ATOM 1154 N NH2 . ARG A 1 145 ? 45.293 7.827 129.631 1.00 9.15 ? 224 ARG N NH2 1 ATOM 1155 N N . THR A 1 146 ? 52.413 6.291 134.478 1.00 4.37 ? 225 THR N N 1 ATOM 1156 C CA . THR A 1 146 ? 52.785 7.053 135.672 1.00 2.79 ? 225 THR N CA 1 ATOM 1157 C C . THR A 1 146 ? 53.785 8.206 135.479 1.00 4.44 ? 225 THR N C 1 ATOM 1158 O O . THR A 1 146 ? 54.292 8.451 134.390 1.00 6.34 ? 225 THR N O 1 ATOM 1159 C CB . THR A 1 146 ? 53.336 6.074 136.676 1.00 5.11 ? 225 THR N CB 1 ATOM 1160 O OG1 . THR A 1 146 ? 53.260 6.749 137.933 1.00 8.05 ? 225 THR N OG1 1 ATOM 1161 C CG2 . THR A 1 146 ? 54.732 5.631 136.389 1.00 5.70 ? 225 THR N CG2 1 ATOM 1162 N N . GLN A 1 147 ? 54.217 8.877 136.562 1.00 5.81 ? 226 GLN N N 1 ATOM 1163 C CA . GLN A 1 147 ? 55.099 10.051 136.558 1.00 5.01 ? 226 GLN N CA 1 ATOM 1164 C C . GLN A 1 147 ? 56.041 10.398 135.455 1.00 2.00 ? 226 GLN N C 1 ATOM 1165 O O . GLN A 1 147 ? 55.985 11.536 135.026 1.00 4.33 ? 226 GLN N O 1 ATOM 1166 C CB . GLN A 1 147 ? 56.043 10.122 137.789 1.00 4.96 ? 226 GLN N CB 1 ATOM 1167 C CG . GLN A 1 147 ? 55.884 11.091 138.982 1.00 3.27 ? 226 GLN N CG 1 ATOM 1168 C CD . GLN A 1 147 ? 54.848 10.688 139.999 1.00 2.00 ? 226 GLN N CD 1 ATOM 1169 O OE1 . GLN A 1 147 ? 54.807 11.076 141.163 1.00 3.53 ? 226 GLN N OE1 1 ATOM 1170 N NE2 . GLN A 1 147 ? 53.863 9.910 139.583 1.00 2.85 ? 226 GLN N NE2 1 ATOM 1171 N N . GLU A 1 148 ? 56.906 9.526 135.001 1.00 3.45 ? 227 GLU N N 1 ATOM 1172 C CA . GLU A 1 148 ? 58.009 9.881 134.090 1.00 4.24 ? 227 GLU N CA 1 ATOM 1173 C C . GLU A 1 148 ? 59.138 10.785 134.625 1.00 4.63 ? 227 GLU N C 1 ATOM 1174 O O . GLU A 1 148 ? 59.991 11.294 133.888 1.00 2.69 ? 227 GLU N O 1 ATOM 1175 C CB . GLU A 1 148 ? 57.436 10.502 132.808 1.00 3.16 ? 227 GLU N CB 1 ATOM 1176 C CG . GLU A 1 148 ? 57.366 9.543 131.690 1.00 2.09 ? 227 GLU N CG 1 ATOM 1177 C CD . GLU A 1 148 ? 56.880 8.177 132.141 1.00 5.25 ? 227 GLU N CD 1 ATOM 1178 O OE1 . GLU A 1 148 ? 57.724 7.362 132.542 1.00 7.02 ? 227 GLU N OE1 1 ATOM 1179 O OE2 . GLU A 1 148 ? 55.664 7.946 132.060 1.00 5.93 ? 227 GLU N OE2 1 ATOM 1180 N N . SER A 1 149 ? 59.200 10.949 135.946 1.00 5.91 ? 228 SER N N 1 ATOM 1181 C CA . SER A 1 149 ? 60.242 11.652 136.652 1.00 6.70 ? 228 SER N CA 1 ATOM 1182 C C . SER A 1 149 ? 60.168 11.140 138.086 1.00 7.52 ? 228 SER N C 1 ATOM 1183 O O . SER A 1 149 ? 59.301 10.332 138.475 1.00 9.23 ? 228 SER N O 1 ATOM 1184 C CB . SER A 1 149 ? 59.988 13.136 136.542 1.00 10.19 ? 228 SER N CB 1 ATOM 1185 O OG . SER A 1 149 ? 58.686 13.601 136.893 1.00 10.94 ? 228 SER N OG 1 ATOM 1186 N N . GLU A 1 150 ? 61.141 11.521 138.887 1.00 10.02 ? 229 GLU N N 1 ATOM 1187 C CA . GLU A 1 150 ? 61.172 11.148 140.296 1.00 12.85 ? 229 GLU N CA 1 ATOM 1188 C C . GLU A 1 150 ? 59.965 11.519 141.126 1.00 14.41 ? 229 GLU N C 1 ATOM 1189 O O . GLU A 1 150 ? 59.286 12.539 140.900 1.00 17.40 ? 229 GLU N O 1 ATOM 1190 C CB . GLU A 1 150 ? 62.392 11.752 140.989 1.00 13.35 ? 229 GLU N CB 1 ATOM 1191 C CG . GLU A 1 150 ? 62.395 13.235 141.309 1.00 14.81 ? 229 GLU N CG 1 ATOM 1192 C CD . GLU A 1 150 ? 63.459 13.624 142.322 1.00 16.67 ? 229 GLU N CD 1 ATOM 1193 O OE1 . GLU A 1 150 ? 64.395 12.865 142.549 1.00 17.13 ? 229 GLU N OE1 1 ATOM 1194 O OE2 . GLU A 1 150 ? 63.343 14.690 142.909 1.00 19.30 ? 229 GLU N OE2 1 ATOM 1195 N N . CYS A 1 151 ? 59.733 10.619 142.069 1.00 12.26 ? 230 CYS N N 1 ATOM 1196 C CA . CYS A 1 151 ? 58.638 10.808 143.000 1.00 10.11 ? 230 CYS N CA 1 ATOM 1197 C C . CYS A 1 151 ? 59.193 11.492 144.239 1.00 9.85 ? 230 CYS N C 1 ATOM 1198 O O . CYS A 1 151 ? 60.396 11.749 144.252 1.00 8.72 ? 230 CYS N O 1 ATOM 1199 C CB . CYS A 1 151 ? 57.975 9.426 143.347 1.00 8.88 ? 230 CYS N CB 1 ATOM 1200 S SG . CYS A 1 151 ? 59.015 7.954 143.539 1.00 3.51 ? 230 CYS N SG 1 ATOM 1201 N N . VAL A 1 152 ? 58.415 11.872 145.267 1.00 11.33 ? 231 VAL N N 1 ATOM 1202 C CA . VAL A 1 152 ? 58.931 12.446 146.504 1.00 10.15 ? 231 VAL N CA 1 ATOM 1203 C C . VAL A 1 152 ? 58.381 11.709 147.718 1.00 8.17 ? 231 VAL N C 1 ATOM 1204 O O . VAL A 1 152 ? 57.186 11.426 147.774 1.00 4.81 ? 231 VAL N O 1 ATOM 1205 C CB . VAL A 1 152 ? 58.560 13.907 146.635 1.00 10.27 ? 231 VAL N CB 1 ATOM 1206 C CG1 . VAL A 1 152 ? 59.333 14.488 147.815 1.00 11.35 ? 231 VAL N CG1 1 ATOM 1207 C CG2 . VAL A 1 152 ? 58.987 14.691 145.420 1.00 11.19 ? 231 VAL N CG2 1 ATOM 1208 N N . CYS A 1 153 ? 59.251 11.381 148.668 1.00 7.56 ? 232 CYS N N 1 ATOM 1209 C CA . CYS A 1 153 ? 58.917 10.674 149.863 1.00 4.17 ? 232 CYS N CA 1 ATOM 1210 C C . CYS A 1 153 ? 59.036 11.490 151.117 1.00 6.41 ? 232 CYS N C 1 ATOM 1211 O O . CYS A 1 153 ? 60.055 12.150 151.276 1.00 8.11 ? 232 CYS N O 1 ATOM 1212 C CB . CYS A 1 153 ? 59.836 9.486 150.073 1.00 5.82 ? 232 CYS N CB 1 ATOM 1213 S SG . CYS A 1 153 ? 59.884 8.067 148.923 1.00 4.05 ? 232 CYS N SG 1 ATOM 1214 N N . HIS A 1 154 ? 58.059 11.445 152.026 1.00 7.17 ? 233 HIS N N 1 ATOM 1215 C CA . HIS A 1 154 ? 58.155 12.030 153.374 1.00 8.85 ? 233 HIS N CA 1 ATOM 1216 C C . HIS A 1 154 ? 58.025 10.983 154.477 1.00 7.32 ? 233 HIS N C 1 ATOM 1217 O O . HIS A 1 154 ? 56.968 10.357 154.666 1.00 6.33 ? 233 HIS N O 1 ATOM 1218 C CB . HIS A 1 154 ? 57.052 13.031 153.572 1.00 7.62 ? 233 HIS N CB 1 ATOM 1219 C CG . HIS A 1 154 ? 57.146 13.903 154.807 1.00 5.34 ? 233 HIS N CG 1 ATOM 1220 N ND1 . HIS A 1 154 ? 57.851 15.032 154.969 1.00 5.42 ? 233 HIS N ND1 1 ATOM 1221 C CD2 . HIS A 1 154 ? 56.479 13.636 155.984 1.00 4.95 ? 233 HIS N CD2 1 ATOM 1222 C CE1 . HIS A 1 154 ? 57.640 15.451 156.195 1.00 5.18 ? 233 HIS N CE1 1 ATOM 1223 N NE2 . HIS A 1 154 ? 56.819 14.609 156.801 1.00 4.91 ? 233 HIS N NE2 1 ATOM 1224 N N . ASN A 1 155 ? 59.053 10.764 155.265 1.00 11.13 ? 234 ASN N N 1 ATOM 1225 C CA . ASN A 1 155 ? 59.055 9.775 156.356 1.00 13.81 ? 234 ASN N CA 1 ATOM 1226 C C . ASN A 1 155 ? 58.669 8.348 155.918 1.00 15.85 ? 234 ASN N C 1 ATOM 1227 O O . ASN A 1 155 ? 57.901 7.644 156.561 1.00 20.03 ? 234 ASN N O 1 ATOM 1228 C CB . ASN A 1 155 ? 58.123 10.282 157.482 1.00 17.37 ? 234 ASN N CB 1 ATOM 1229 C CG . ASN A 1 155 ? 58.196 9.470 158.755 1.00 18.37 ? 234 ASN N CG 1 ATOM 1230 O OD1 . ASN A 1 155 ? 59.267 9.238 159.304 1.00 20.20 ? 234 ASN N OD1 1 ATOM 1231 N ND2 . ASN A 1 155 ? 57.088 8.993 159.292 1.00 21.47 ? 234 ASN N ND2 1 ATOM 1232 N N . GLY A 1 156 ? 59.193 7.818 154.808 1.00 14.46 ? 235 GLY N N 1 ATOM 1233 C CA . GLY A 1 156 ? 58.839 6.482 154.358 1.00 9.63 ? 235 GLY N CA 1 ATOM 1234 C C . GLY A 1 156 ? 57.756 6.438 153.293 1.00 8.90 ? 235 GLY N C 1 ATOM 1235 O O . GLY A 1 156 ? 57.767 5.500 152.490 1.00 10.26 ? 235 GLY N O 1 ATOM 1236 N N . VAL A 1 157 ? 56.822 7.404 153.321 1.00 7.40 ? 236 VAL N N 1 ATOM 1237 C CA . VAL A 1 157 ? 55.689 7.511 152.418 1.00 5.02 ? 236 VAL N CA 1 ATOM 1238 C C . VAL A 1 157 ? 55.946 8.340 151.200 1.00 3.97 ? 236 VAL N C 1 ATOM 1239 O O . VAL A 1 157 ? 56.234 9.531 151.298 1.00 9.42 ? 236 VAL N O 1 ATOM 1240 C CB . VAL A 1 157 ? 54.528 8.101 153.172 1.00 4.48 ? 236 VAL N CB 1 ATOM 1241 C CG1 . VAL A 1 157 ? 53.277 8.352 152.375 1.00 5.76 ? 236 VAL N CG1 1 ATOM 1242 C CG2 . VAL A 1 157 ? 54.111 7.017 154.100 1.00 4.03 ? 236 VAL N CG2 1 ATOM 1243 N N . CYS A 1 158 ? 55.689 7.717 150.061 1.00 4.79 ? 237 CYS N N 1 ATOM 1244 C CA . CYS A 1 158 ? 55.922 8.285 148.741 1.00 4.68 ? 237 CYS N CA 1 ATOM 1245 C C . CYS A 1 158 ? 54.620 8.329 147.949 1.00 5.42 ? 237 CYS N C 1 ATOM 1246 O O . CYS A 1 158 ? 54.162 7.257 147.554 1.00 9.55 ? 237 CYS N O 1 ATOM 1247 C CB . CYS A 1 158 ? 56.923 7.412 148.053 1.00 4.15 ? 237 CYS N CB 1 ATOM 1248 S SG . CYS A 1 158 ? 58.219 7.016 149.248 1.00 9.08 ? 237 CYS N SG 1 ATOM 1249 N N . PRO A 1 159 ? 53.873 9.410 147.766 1.00 4.94 ? 238 PRO N N 1 ATOM 1250 C CA . PRO A 1 159 ? 52.782 9.425 146.818 1.00 2.63 ? 238 PRO N CA 1 ATOM 1251 C C . PRO A 1 159 ? 53.277 9.354 145.378 1.00 6.12 ? 238 PRO N C 1 ATOM 1252 O O . PRO A 1 159 ? 54.197 10.077 144.963 1.00 6.31 ? 238 PRO N O 1 ATOM 1253 C CB . PRO A 1 159 ? 52.041 10.688 147.137 1.00 2.88 ? 238 PRO N CB 1 ATOM 1254 C CG . PRO A 1 159 ? 53.062 11.559 147.844 1.00 4.36 ? 238 PRO N CG 1 ATOM 1255 C CD . PRO A 1 159 ? 53.854 10.556 148.665 1.00 5.17 ? 238 PRO N CD 1 ATOM 1256 N N . VAL A 1 160 ? 52.641 8.444 144.618 1.00 7.91 ? 239 VAL N N 1 ATOM 1257 C CA . VAL A 1 160 ? 52.930 8.214 143.209 1.00 5.85 ? 239 VAL N CA 1 ATOM 1258 C C . VAL A 1 160 ? 51.559 8.331 142.527 1.00 6.51 ? 239 VAL N C 1 ATOM 1259 O O . VAL A 1 160 ? 50.573 7.750 142.966 1.00 6.16 ? 239 VAL N O 1 ATOM 1260 C CB . VAL A 1 160 ? 53.570 6.773 142.984 1.00 4.10 ? 239 VAL N CB 1 ATOM 1261 C CG1 . VAL A 1 160 ? 54.118 6.676 141.602 1.00 2.51 ? 239 VAL N CG1 1 ATOM 1262 C CG2 . VAL A 1 160 ? 54.830 6.513 143.823 1.00 3.74 ? 239 VAL N CG2 1 ATOM 1263 N N . VAL A 1 161 ? 51.447 9.142 141.478 1.00 5.52 ? 240 VAL N N 1 ATOM 1264 C CA . VAL A 1 161 ? 50.210 9.363 140.781 1.00 4.19 ? 240 VAL N CA 1 ATOM 1265 C C . VAL A 1 161 ? 50.224 8.481 139.552 1.00 5.99 ? 240 VAL N C 1 ATOM 1266 O O . VAL A 1 161 ? 51.235 8.522 138.837 1.00 7.91 ? 240 VAL N O 1 ATOM 1267 C CB . VAL A 1 161 ? 50.115 10.820 140.371 1.00 5.18 ? 240 VAL N CB 1 ATOM 1268 C CG1 . VAL A 1 161 ? 48.738 11.062 139.757 1.00 2.11 ? 240 VAL N CG1 1 ATOM 1269 C CG2 . VAL A 1 161 ? 50.215 11.725 141.567 1.00 3.83 ? 240 VAL N CG2 1 ATOM 1270 N N . PHE A 1 162 ? 49.147 7.706 139.323 1.00 7.78 ? 241 PHE N N 1 ATOM 1271 C CA . PHE A 1 162 ? 49.012 6.812 138.179 1.00 10.41 ? 241 PHE N CA 1 ATOM 1272 C C . PHE A 1 162 ? 47.769 7.140 137.397 1.00 7.91 ? 241 PHE N C 1 ATOM 1273 O O . PHE A 1 162 ? 46.753 7.418 138.035 1.00 10.23 ? 241 PHE N O 1 ATOM 1274 C CB . PHE A 1 162 ? 48.823 5.330 138.534 1.00 8.60 ? 241 PHE N CB 1 ATOM 1275 C CG . PHE A 1 162 ? 49.968 4.600 139.225 1.00 8.69 ? 241 PHE N CG 1 ATOM 1276 C CD1 . PHE A 1 162 ? 50.157 4.715 140.590 1.00 9.46 ? 241 PHE N CD1 1 ATOM 1277 C CD2 . PHE A 1 162 ? 50.821 3.825 138.469 1.00 8.86 ? 241 PHE N CD2 1 ATOM 1278 C CE1 . PHE A 1 162 ? 51.207 4.059 141.182 1.00 10.02 ? 241 PHE N CE1 1 ATOM 1279 C CE2 . PHE A 1 162 ? 51.865 3.168 139.067 1.00 8.92 ? 241 PHE N CE2 1 ATOM 1280 C CZ . PHE A 1 162 ? 52.054 3.287 140.421 1.00 9.79 ? 241 PHE N CZ 1 ATOM 1281 N N . THR A 1 163 ? 47.761 7.069 136.075 1.00 6.36 ? 242 THR N N 1 ATOM 1282 C CA . THR A 1 163 ? 46.506 7.254 135.349 1.00 9.03 ? 242 THR N CA 1 ATOM 1283 C C . THR A 1 163 ? 46.213 5.999 134.567 1.00 8.38 ? 242 THR N C 1 ATOM 1284 O O . THR A 1 163 ? 47.168 5.395 134.067 1.00 11.52 ? 242 THR N O 1 ATOM 1285 C CB . THR A 1 163 ? 46.626 8.427 134.417 1.00 10.90 ? 242 THR N CB 1 ATOM 1286 O OG1 . THR A 1 163 ? 47.164 9.438 135.290 1.00 14.51 ? 242 THR N OG1 1 ATOM 1287 C CG2 . THR A 1 163 ? 45.309 8.868 133.724 1.00 11.65 ? 242 THR N CG2 1 ATOM 1288 N N . ASP A 1 164 ? 44.989 5.519 134.479 1.00 5.26 ? 243 ASP N N 1 ATOM 1289 C CA . ASP A 1 164 ? 44.756 4.384 133.636 1.00 8.91 ? 243 ASP N CA 1 ATOM 1290 C C . ASP A 1 164 ? 43.523 4.759 132.866 1.00 8.53 ? 243 ASP N C 1 ATOM 1291 O O . ASP A 1 164 ? 42.532 5.144 133.508 1.00 10.95 ? 243 ASP N O 1 ATOM 1292 C CB . ASP A 1 164 ? 44.462 3.160 134.429 1.00 7.00 ? 243 ASP N CB 1 ATOM 1293 C CG . ASP A 1 164 ? 44.342 1.803 133.712 1.00 5.07 ? 243 ASP N CG 1 ATOM 1294 O OD1 . ASP A 1 164 ? 44.312 1.642 132.476 1.00 2.23 ? 243 ASP N OD1 1 ATOM 1295 O OD2 . ASP A 1 164 ? 44.288 0.852 134.480 1.00 6.23 ? 243 ASP N OD2 1 ATOM 1296 N N . GLY A 1 165 ? 43.503 4.710 131.546 1.00 9.74 ? 244 GLY N N 1 ATOM 1297 C CA . GLY A 1 165 ? 42.302 5.087 130.876 1.00 12.64 ? 244 GLY N CA 1 ATOM 1298 C C . GLY A 1 165 ? 42.678 5.857 129.636 1.00 16.01 ? 244 GLY N C 1 ATOM 1299 O O . GLY A 1 165 ? 43.798 5.672 129.128 1.00 14.12 ? 244 GLY N O 1 ATOM 1300 N N . SER A 1 166 ? 41.762 6.721 129.158 1.00 17.01 ? 245 SER N N 1 ATOM 1301 C CA . SER A 1 166 ? 41.950 7.299 127.858 1.00 19.84 ? 245 SER N CA 1 ATOM 1302 C C . SER A 1 166 ? 42.650 8.628 127.949 1.00 19.52 ? 245 SER N C 1 ATOM 1303 O O . SER A 1 166 ? 42.415 9.378 128.885 1.00 20.10 ? 245 SER N O 1 ATOM 1304 C CB . SER A 1 166 ? 40.611 7.482 127.200 1.00 23.18 ? 245 SER N CB 1 ATOM 1305 O OG . SER A 1 166 ? 40.788 7.885 125.841 1.00 30.44 ? 245 SER N OG 1 ATOM 1306 N N . ALA A 1 167 ? 43.488 8.939 126.970 1.00 17.40 ? 246 ALA N N 1 ATOM 1307 C CA . ALA A 1 167 ? 44.142 10.219 126.957 1.00 19.76 ? 246 ALA N CA 1 ATOM 1308 C C . ALA A 1 167 ? 43.286 11.236 126.241 1.00 21.41 ? 246 ALA N C 1 ATOM 1309 O O . ALA A 1 167 ? 43.667 12.395 126.087 1.00 23.82 ? 246 ALA N O 1 ATOM 1310 C CB . ALA A 1 167 ? 45.475 10.104 126.249 1.00 18.12 ? 246 ALA N CB 1 ATOM 1311 N N . THR A 1 168 ? 42.129 10.794 125.778 1.00 24.44 ? 247 THR N N 1 ATOM 1312 C CA . THR A 1 168 ? 41.158 11.577 125.039 1.00 24.56 ? 247 THR N CA 1 ATOM 1313 C C . THR A 1 168 ? 39.907 11.439 125.888 1.00 23.34 ? 247 THR N C 1 ATOM 1314 O O . THR A 1 168 ? 39.019 10.624 125.631 1.00 25.36 ? 247 THR N O 1 ATOM 1315 C CB . THR A 1 168 ? 41.069 10.919 123.674 1.00 23.91 ? 247 THR N CB 1 ATOM 1316 O OG1 . THR A 1 168 ? 42.322 11.217 123.089 1.00 27.04 ? 247 THR N OG1 1 ATOM 1317 C CG2 . THR A 1 168 ? 39.971 11.399 122.794 1.00 25.79 ? 247 THR N CG2 1 ATOM 1318 N N . GLY A 1 169 ? 39.875 12.098 127.022 1.00 22.35 ? 248 GLY N N 1 ATOM 1319 C CA . GLY A 1 169 ? 38.665 11.986 127.816 1.00 22.01 ? 248 GLY N CA 1 ATOM 1320 C C . GLY A 1 169 ? 38.899 11.507 129.234 1.00 23.14 ? 248 GLY N C 1 ATOM 1321 O O . GLY A 1 169 ? 40.048 11.233 129.590 1.00 23.10 ? 248 GLY N O 1 ATOM 1322 N N . PRO A 1 170 ? 37.857 11.438 130.075 1.00 23.86 ? 249 PRO N N 1 ATOM 1323 C CA . PRO A 1 170 ? 37.934 10.976 131.460 1.00 23.19 ? 249 PRO N CA 1 ATOM 1324 C C . PRO A 1 170 ? 38.717 9.662 131.632 1.00 22.32 ? 249 PRO N C 1 ATOM 1325 O O . PRO A 1 170 ? 38.425 8.681 130.937 1.00 24.09 ? 249 PRO N O 1 ATOM 1326 C CB . PRO A 1 170 ? 36.466 10.897 131.866 1.00 19.94 ? 249 PRO N CB 1 ATOM 1327 C CG . PRO A 1 170 ? 35.743 10.701 130.565 1.00 20.74 ? 249 PRO N CG 1 ATOM 1328 C CD . PRO A 1 170 ? 36.478 11.680 129.690 1.00 22.47 ? 249 PRO N CD 1 ATOM 1329 N N . ALA A 1 171 ? 39.702 9.611 132.528 1.00 20.93 ? 250 ALA N N 1 ATOM 1330 C CA . ALA A 1 171 ? 40.525 8.430 132.736 1.00 18.73 ? 250 ALA N CA 1 ATOM 1331 C C . ALA A 1 171 ? 40.632 8.127 134.235 1.00 17.52 ? 250 ALA N C 1 ATOM 1332 O O . ALA A 1 171 ? 40.438 9.042 135.038 1.00 19.71 ? 250 ALA N O 1 ATOM 1333 C CB . ALA A 1 171 ? 41.903 8.707 132.147 1.00 17.47 ? 250 ALA N CB 1 ATOM 1334 N N . GLU A 1 172 ? 40.912 6.912 134.723 1.00 16.10 ? 251 GLU N N 1 ATOM 1335 C CA . GLU A 1 172 ? 41.021 6.660 136.159 1.00 14.85 ? 251 GLU N CA 1 ATOM 1336 C C . GLU A 1 172 ? 42.399 6.918 136.726 1.00 15.68 ? 251 GLU N C 1 ATOM 1337 O O . GLU A 1 172 ? 43.287 6.067 136.585 1.00 15.61 ? 251 GLU N O 1 ATOM 1338 C CB . GLU A 1 172 ? 40.683 5.238 136.514 1.00 17.47 ? 251 GLU N CB 1 ATOM 1339 C CG . GLU A 1 172 ? 39.221 5.070 136.749 1.00 20.32 ? 251 GLU N CG 1 ATOM 1340 C CD . GLU A 1 172 ? 38.772 3.611 136.813 1.00 21.75 ? 251 GLU N CD 1 ATOM 1341 O OE1 . GLU A 1 172 ? 38.753 2.958 135.762 1.00 22.09 ? 251 GLU N OE1 1 ATOM 1342 O OE2 . GLU A 1 172 ? 38.410 3.128 137.895 1.00 24.61 ? 251 GLU N OE2 1 ATOM 1343 N N . THR A 1 173 ? 42.590 8.145 137.249 1.00 12.08 ? 252 THR N N 1 ATOM 1344 C CA . THR A 1 173 ? 43.791 8.572 137.947 1.00 8.06 ? 252 THR N CA 1 ATOM 1345 C C . THR A 1 173 ? 43.597 8.288 139.427 1.00 9.40 ? 252 THR N C 1 ATOM 1346 O O . THR A 1 173 ? 42.606 8.778 139.967 1.00 9.58 ? 252 THR N O 1 ATOM 1347 C CB . THR A 1 173 ? 44.038 10.072 137.818 1.00 7.58 ? 252 THR N CB 1 ATOM 1348 O OG1 . THR A 1 173 ? 44.190 10.449 136.460 1.00 5.42 ? 252 THR N OG1 1 ATOM 1349 C CG2 . THR A 1 173 ? 45.314 10.441 138.553 1.00 8.88 ? 252 THR N CG2 1 ATOM 1350 N N . ARG A 1 174 ? 44.519 7.571 140.088 1.00 12.41 ? 253 ARG N N 1 ATOM 1351 C CA . ARG A 1 174 ? 44.517 7.308 141.531 1.00 10.22 ? 253 ARG N CA 1 ATOM 1352 C C . ARG A 1 174 ? 45.879 7.721 142.058 1.00 11.37 ? 253 ARG N C 1 ATOM 1353 O O . ARG A 1 174 ? 46.894 7.511 141.379 1.00 10.96 ? 253 ARG N O 1 ATOM 1354 C CB . ARG A 1 174 ? 44.396 5.822 141.946 1.00 10.69 ? 253 ARG N CB 1 ATOM 1355 C CG . ARG A 1 174 ? 43.746 4.872 140.942 1.00 10.98 ? 253 ARG N CG 1 ATOM 1356 C CD . ARG A 1 174 ? 42.477 4.181 141.346 1.00 12.17 ? 253 ARG N CD 1 ATOM 1357 N NE . ARG A 1 174 ? 42.688 2.737 141.537 1.00 13.33 ? 253 ARG N NE 1 ATOM 1358 C CZ . ARG A 1 174 ? 41.868 1.790 141.061 1.00 13.86 ? 253 ARG N CZ 1 ATOM 1359 N NH1 . ARG A 1 174 ? 40.820 2.076 140.316 1.00 13.40 ? 253 ARG N NH1 1 ATOM 1360 N NH2 . ARG A 1 174 ? 42.147 0.533 141.320 1.00 12.98 ? 253 ARG N NH2 1 ATOM 1361 N N . ILE A 1 175 ? 45.893 8.321 143.252 1.00 11.79 ? 254 ILE N N 1 ATOM 1362 C CA . ILE A 1 175 ? 47.121 8.638 143.989 1.00 13.41 ? 254 ILE N CA 1 ATOM 1363 C C . ILE A 1 175 ? 47.374 7.443 144.954 1.00 12.89 ? 254 ILE N C 1 ATOM 1364 O O . ILE A 1 175 ? 46.529 7.066 145.782 1.00 13.67 ? 254 ILE N O 1 ATOM 1365 C CB . ILE A 1 175 ? 46.989 10.016 144.819 1.00 14.09 ? 254 ILE N CB 1 ATOM 1366 C CG1 . ILE A 1 175 ? 46.987 11.269 143.965 1.00 12.76 ? 254 ILE N CG1 1 ATOM 1367 C CG2 . ILE A 1 175 ? 48.196 10.169 145.726 1.00 15.27 ? 254 ILE N CG2 1 ATOM 1368 C CD1 . ILE A 1 175 ? 45.735 11.434 143.094 1.00 16.23 ? 254 ILE N CD1 1 ATOM 1369 N N . TYR A 1 176 ? 48.525 6.772 144.823 1.00 11.91 ? 255 TYR N N 1 ATOM 1370 C CA . TYR A 1 176 ? 48.935 5.679 145.700 1.00 8.60 ? 255 TYR N CA 1 ATOM 1371 C C . TYR A 1 176 ? 49.961 6.158 146.704 1.00 11.20 ? 255 TYR N C 1 ATOM 1372 O O . TYR A 1 176 ? 50.863 6.953 146.382 1.00 10.64 ? 255 TYR N O 1 ATOM 1373 C CB . TYR A 1 176 ? 49.556 4.523 144.914 1.00 8.08 ? 255 TYR N CB 1 ATOM 1374 C CG . TYR A 1 176 ? 48.544 3.488 144.372 1.00 7.85 ? 255 TYR N CG 1 ATOM 1375 C CD1 . TYR A 1 176 ? 47.824 3.711 143.205 1.00 9.61 ? 255 TYR N CD1 1 ATOM 1376 C CD2 . TYR A 1 176 ? 48.350 2.313 145.057 1.00 6.08 ? 255 TYR N CD2 1 ATOM 1377 C CE1 . TYR A 1 176 ? 46.940 2.779 142.715 1.00 6.94 ? 255 TYR N CE1 1 ATOM 1378 C CE2 . TYR A 1 176 ? 47.464 1.378 144.568 1.00 6.63 ? 255 TYR N CE2 1 ATOM 1379 C CZ . TYR A 1 176 ? 46.767 1.613 143.408 1.00 5.60 ? 255 TYR N CZ 1 ATOM 1380 O OH . TYR A 1 176 ? 45.898 0.645 142.946 1.00 4.07 ? 255 TYR N OH 1 ATOM 1381 N N . TYR A 1 177 ? 49.828 5.711 147.958 1.00 12.76 ? 256 TYR N N 1 ATOM 1382 C CA . TYR A 1 177 ? 50.787 6.071 148.997 1.00 12.84 ? 256 TYR N CA 1 ATOM 1383 C C . TYR A 1 177 ? 51.510 4.775 149.332 1.00 13.21 ? 256 TYR N C 1 ATOM 1384 O O . TYR A 1 177 ? 50.901 3.813 149.805 1.00 14.53 ? 256 TYR N O 1 ATOM 1385 C CB . TYR A 1 177 ? 50.110 6.603 150.251 1.00 9.11 ? 256 TYR N CB 1 ATOM 1386 C CG . TYR A 1 177 ? 49.328 7.847 149.958 1.00 6.99 ? 256 TYR N CG 1 ATOM 1387 C CD1 . TYR A 1 177 ? 48.064 7.766 149.417 1.00 8.78 ? 256 TYR N CD1 1 ATOM 1388 C CD2 . TYR A 1 177 ? 49.886 9.063 150.193 1.00 10.04 ? 256 TYR N CD2 1 ATOM 1389 C CE1 . TYR A 1 177 ? 47.325 8.879 149.098 1.00 7.39 ? 256 TYR N CE1 1 ATOM 1390 C CE2 . TYR A 1 177 ? 49.149 10.198 149.880 1.00 11.19 ? 256 TYR N CE2 1 ATOM 1391 C CZ . TYR A 1 177 ? 47.879 10.105 149.332 1.00 8.82 ? 256 TYR N CZ 1 ATOM 1392 O OH . TYR A 1 177 ? 47.153 11.244 149.027 1.00 10.49 ? 256 TYR N OH 1 ATOM 1393 N N . PHE A 1 178 ? 52.796 4.691 149.035 1.00 11.64 ? 257 PHE N N 1 ATOM 1394 C CA . PHE A 1 178 ? 53.531 3.499 149.356 1.00 11.76 ? 257 PHE N CA 1 ATOM 1395 C C . PHE A 1 178 ? 54.374 3.819 150.571 1.00 14.76 ? 257 PHE N C 1 ATOM 1396 O O . PHE A 1 178 ? 54.595 5.003 150.873 1.00 14.96 ? 257 PHE N O 1 ATOM 1397 C CB . PHE A 1 178 ? 54.470 3.116 148.239 1.00 8.32 ? 257 PHE N CB 1 ATOM 1398 C CG . PHE A 1 178 ? 53.854 2.693 146.927 1.00 5.77 ? 257 PHE N CG 1 ATOM 1399 C CD1 . PHE A 1 178 ? 53.482 1.371 146.754 1.00 4.28 ? 257 PHE N CD1 1 ATOM 1400 C CD2 . PHE A 1 178 ? 53.690 3.605 145.892 1.00 7.08 ? 257 PHE N CD2 1 ATOM 1401 C CE1 . PHE A 1 178 ? 52.940 0.993 145.536 1.00 3.47 ? 257 PHE N CE1 1 ATOM 1402 C CE2 . PHE A 1 178 ? 53.156 3.226 144.669 1.00 6.91 ? 257 PHE N CE2 1 ATOM 1403 C CZ . PHE A 1 178 ? 52.781 1.912 144.498 1.00 2.69 ? 257 PHE N CZ 1 ATOM 1404 N N . LYS A 1 179 ? 54.843 2.820 151.297 1.00 16.22 ? 258 LYS N N 1 ATOM 1405 C CA . LYS A 1 179 ? 55.869 3.068 152.291 1.00 19.43 ? 258 LYS N CA 1 ATOM 1406 C C . LYS A 1 179 ? 56.732 1.839 152.162 1.00 21.15 ? 258 LYS N C 1 ATOM 1407 O O . LYS A 1 179 ? 56.234 0.738 152.375 1.00 22.63 ? 258 LYS N O 1 ATOM 1408 C CB . LYS A 1 179 ? 55.379 3.122 153.738 1.00 23.67 ? 258 LYS N CB 1 ATOM 1409 C CG . LYS A 1 179 ? 56.485 3.479 154.717 1.00 27.08 ? 258 LYS N CG 1 ATOM 1410 C CD . LYS A 1 179 ? 56.065 3.467 156.168 1.00 32.41 ? 258 LYS N CD 1 ATOM 1411 C CE . LYS A 1 179 ? 57.172 4.203 156.938 1.00 37.11 ? 258 LYS N CE 1 ATOM 1412 N NZ . LYS A 1 179 ? 56.896 4.397 158.363 1.00 42.09 ? 258 LYS N NZ 1 ATOM 1413 N N . GLU A 1 180 ? 57.979 1.947 151.711 1.00 20.69 ? 259 GLU N N 1 ATOM 1414 C CA . GLU A 1 180 ? 58.859 0.792 151.683 1.00 18.55 ? 259 GLU N CA 1 ATOM 1415 C C . GLU A 1 180 ? 58.387 -0.290 150.753 1.00 18.47 ? 259 GLU N C 1 ATOM 1416 O O . GLU A 1 180 ? 58.549 -1.477 151.048 1.00 20.81 ? 259 GLU N O 1 ATOM 1417 C CB . GLU A 1 180 ? 59.026 0.112 153.055 1.00 19.14 ? 259 GLU N CB 1 ATOM 1418 C CG . GLU A 1 180 ? 59.704 0.915 154.139 1.00 21.83 ? 259 GLU N CG 1 ATOM 1419 C CD . GLU A 1 180 ? 59.894 0.041 155.350 1.00 23.96 ? 259 GLU N CD 1 ATOM 1420 O OE1 . GLU A 1 180 ? 58.903 -0.279 156.021 1.00 25.07 ? 259 GLU N OE1 1 ATOM 1421 O OE2 . GLU A 1 180 ? 61.045 -0.326 155.582 1.00 25.91 ? 259 GLU N OE2 1 ATOM 1422 N N . GLY A 1 181 ? 57.750 0.089 149.649 1.00 17.05 ? 260 GLY N N 1 ATOM 1423 C CA . GLY A 1 181 ? 57.350 -0.941 148.701 1.00 11.72 ? 260 GLY N CA 1 ATOM 1424 C C . GLY A 1 181 ? 55.916 -1.404 148.883 1.00 8.27 ? 260 GLY N C 1 ATOM 1425 O O . GLY A 1 181 ? 55.316 -1.636 147.832 1.00 6.00 ? 260 GLY N O 1 ATOM 1426 N N . LYS A 1 182 ? 55.375 -1.562 150.118 1.00 8.35 ? 261 LYS N N 1 ATOM 1427 C CA . LYS A 1 182 ? 53.985 -1.967 150.367 1.00 7.07 ? 261 LYS N CA 1 ATOM 1428 C C . LYS A 1 182 ? 52.996 -0.802 150.127 1.00 9.69 ? 261 LYS N C 1 ATOM 1429 O O . LYS A 1 182 ? 53.364 0.374 150.359 1.00 10.01 ? 261 LYS N O 1 ATOM 1430 C CB . LYS A 1 182 ? 53.867 -2.468 151.804 1.00 7.47 ? 261 LYS N CB 1 ATOM 1431 C CG . LYS A 1 182 ? 52.803 -3.534 152.022 1.00 7.19 ? 261 LYS N CG 1 ATOM 1432 C CD . LYS A 1 182 ? 53.042 -4.253 153.345 1.00 7.28 ? 261 LYS N CD 1 ATOM 1433 C CE . LYS A 1 182 ? 52.005 -5.348 153.532 1.00 7.50 ? 261 LYS N CE 1 ATOM 1434 N NZ . LYS A 1 182 ? 52.241 -6.081 154.762 1.00 8.14 ? 261 LYS N NZ 1 ATOM 1435 N N . ILE A 1 183 ? 51.749 -1.060 149.654 1.00 7.56 ? 262 ILE N N 1 ATOM 1436 C CA . ILE A 1 183 ? 50.788 0.035 149.514 1.00 4.74 ? 262 ILE N CA 1 ATOM 1437 C C . ILE A 1 183 ? 50.173 0.383 150.844 1.00 5.13 ? 262 ILE N C 1 ATOM 1438 O O . ILE A 1 183 ? 49.501 -0.454 151.450 1.00 5.76 ? 262 ILE N O 1 ATOM 1439 C CB . ILE A 1 183 ? 49.593 -0.237 148.563 1.00 4.07 ? 262 ILE N CB 1 ATOM 1440 C CG1 . ILE A 1 183 ? 50.022 -0.736 147.206 1.00 4.83 ? 262 ILE N CG1 1 ATOM 1441 C CG2 . ILE A 1 183 ? 48.930 1.082 148.277 1.00 4.55 ? 262 ILE N CG2 1 ATOM 1442 C CD1 . ILE A 1 183 ? 48.979 -1.583 146.445 1.00 3.12 ? 262 ILE N CD1 1 ATOM 1443 N N . LEU A 1 184 ? 50.359 1.613 151.309 1.00 5.14 ? 263 LEU N N 1 ATOM 1444 C CA . LEU A 1 184 ? 49.707 2.050 152.540 1.00 5.79 ? 263 LEU N CA 1 ATOM 1445 C C . LEU A 1 184 ? 48.258 2.459 152.327 1.00 6.73 ? 263 LEU N C 1 ATOM 1446 O O . LEU A 1 184 ? 47.427 2.259 153.204 1.00 11.03 ? 263 LEU N O 1 ATOM 1447 C CB . LEU A 1 184 ? 50.459 3.205 153.155 1.00 5.25 ? 263 LEU N CB 1 ATOM 1448 C CG . LEU A 1 184 ? 51.737 2.874 153.937 1.00 4.43 ? 263 LEU N CG 1 ATOM 1449 C CD1 . LEU A 1 184 ? 51.949 3.970 154.934 1.00 5.73 ? 263 LEU N CD1 1 ATOM 1450 C CD2 . LEU A 1 184 ? 51.633 1.594 154.764 1.00 4.97 ? 263 LEU N CD2 1 ATOM 1451 N N . LYS A 1 185 ? 47.881 3.013 151.195 1.00 6.56 ? 264 LYS N N 1 ATOM 1452 C CA . LYS A 1 185 ? 46.501 3.320 150.866 1.00 7.51 ? 264 LYS N CA 1 ATOM 1453 C C . LYS A 1 185 ? 46.524 3.952 149.492 1.00 7.84 ? 264 LYS N C 1 ATOM 1454 O O . LYS A 1 185 ? 47.630 4.195 148.966 1.00 6.47 ? 264 LYS N O 1 ATOM 1455 C CB . LYS A 1 185 ? 45.830 4.331 151.852 1.00 5.74 ? 264 LYS N CB 1 ATOM 1456 C CG . LYS A 1 185 ? 45.898 5.867 151.772 1.00 3.83 ? 264 LYS N CG 1 ATOM 1457 C CD . LYS A 1 185 ? 44.423 6.376 151.897 1.00 3.97 ? 264 LYS N CD 1 ATOM 1458 C CE . LYS A 1 185 ? 44.156 7.871 152.223 1.00 3.35 ? 264 LYS N CE 1 ATOM 1459 N NZ . LYS A 1 185 ? 44.223 8.166 153.651 1.00 3.97 ? 264 LYS N NZ 1 ATOM 1460 N N . TRP A 1 186 ? 45.371 4.201 148.868 1.00 9.81 ? 265 TRP N N 1 ATOM 1461 C CA . TRP A 1 186 ? 45.328 4.913 147.606 1.00 11.65 ? 265 TRP N CA 1 ATOM 1462 C C . TRP A 1 186 ? 44.005 5.590 147.558 1.00 13.87 ? 265 TRP N C 1 ATOM 1463 O O . TRP A 1 186 ? 43.006 4.991 148.017 1.00 18.10 ? 265 TRP N O 1 ATOM 1464 C CB . TRP A 1 186 ? 45.384 4.025 146.397 1.00 7.87 ? 265 TRP N CB 1 ATOM 1465 C CG . TRP A 1 186 ? 44.313 2.964 146.207 1.00 7.29 ? 265 TRP N CG 1 ATOM 1466 C CD1 . TRP A 1 186 ? 44.505 1.652 146.578 1.00 9.31 ? 265 TRP N CD1 1 ATOM 1467 C CD2 . TRP A 1 186 ? 43.096 3.156 145.612 1.00 8.08 ? 265 TRP N CD2 1 ATOM 1468 N NE1 . TRP A 1 186 ? 43.415 1.004 146.221 1.00 7.20 ? 265 TRP N NE1 1 ATOM 1469 C CE2 . TRP A 1 186 ? 42.562 1.866 145.648 1.00 6.96 ? 265 TRP N CE2 1 ATOM 1470 C CE3 . TRP A 1 186 ? 42.399 4.217 145.078 1.00 7.20 ? 265 TRP N CE3 1 ATOM 1471 C CZ2 . TRP A 1 186 ? 41.322 1.609 145.145 1.00 5.75 ? 265 TRP N CZ2 1 ATOM 1472 C CZ3 . TRP A 1 186 ? 41.152 3.956 144.572 1.00 6.90 ? 265 TRP N CZ3 1 ATOM 1473 C CH2 . TRP A 1 186 ? 40.630 2.679 144.612 1.00 7.14 ? 265 TRP N CH2 1 ATOM 1474 N N . GLU A 1 187 ? 43.956 6.809 147.062 1.00 13.95 ? 266 GLU N N 1 ATOM 1475 C CA . GLU A 1 187 ? 42.646 7.372 146.867 1.00 13.25 ? 266 GLU N CA 1 ATOM 1476 C C . GLU A 1 187 ? 42.476 7.746 145.420 1.00 12.80 ? 266 GLU N C 1 ATOM 1477 O O . GLU A 1 187 ? 43.463 7.694 144.679 1.00 16.08 ? 266 GLU N O 1 ATOM 1478 C CB . GLU A 1 187 ? 42.492 8.538 147.762 1.00 11.94 ? 266 GLU N CB 1 ATOM 1479 C CG . GLU A 1 187 ? 43.479 9.662 147.671 1.00 14.99 ? 266 GLU N CG 1 ATOM 1480 C CD . GLU A 1 187 ? 43.511 10.520 148.933 1.00 18.07 ? 266 GLU N CD 1 ATOM 1481 O OE1 . GLU A 1 187 ? 42.918 10.160 149.984 1.00 18.78 ? 266 GLU N OE1 1 ATOM 1482 O OE2 . GLU A 1 187 ? 44.175 11.553 148.851 1.00 18.37 ? 266 GLU N OE2 1 ATOM 1483 N N . PRO A 1 188 ? 41.277 7.989 144.899 1.00 11.97 ? 267 PRO N N 1 ATOM 1484 C CA . PRO A 1 188 ? 41.112 8.503 143.539 1.00 12.40 ? 267 PRO N CA 1 ATOM 1485 C C . PRO A 1 188 ? 41.258 9.986 143.342 1.00 10.25 ? 267 PRO N C 1 ATOM 1486 O O . PRO A 1 188 ? 41.083 10.716 144.303 1.00 13.59 ? 267 PRO N O 1 ATOM 1487 C CB . PRO A 1 188 ? 39.768 7.982 143.114 1.00 12.82 ? 267 PRO N CB 1 ATOM 1488 C CG . PRO A 1 188 ? 39.025 7.797 144.389 1.00 11.57 ? 267 PRO N CG 1 ATOM 1489 C CD . PRO A 1 188 ? 40.096 7.251 145.295 1.00 11.41 ? 267 PRO N CD 1 ATOM 1490 N N . LEU A 1 189 ? 41.562 10.471 142.148 1.00 11.46 ? 268 LEU N N 1 ATOM 1491 C CA . LEU A 1 189 ? 41.824 11.872 142.016 1.00 10.82 ? 268 LEU N CA 1 ATOM 1492 C C . LEU A 1 189 ? 40.569 12.682 142.313 1.00 11.41 ? 268 LEU N C 1 ATOM 1493 O O . LEU A 1 189 ? 39.486 12.488 141.758 1.00 12.53 ? 268 LEU N O 1 ATOM 1494 C CB . LEU A 1 189 ? 42.352 12.146 140.615 1.00 6.26 ? 268 LEU N CB 1 ATOM 1495 C CG . LEU A 1 189 ? 42.530 13.535 139.879 1.00 5.59 ? 268 LEU N CG 1 ATOM 1496 C CD1 . LEU A 1 189 ? 41.243 13.866 139.195 1.00 2.99 ? 268 LEU N CD1 1 ATOM 1497 C CD2 . LEU A 1 189 ? 42.889 14.675 140.802 1.00 3.00 ? 268 LEU N CD2 1 ATOM 1498 N N . ALA A 1 190 ? 40.792 13.638 143.194 1.00 12.10 ? 269 ALA N N 1 ATOM 1499 C CA . ALA A 1 190 ? 39.761 14.511 143.657 1.00 13.08 ? 269 ALA N CA 1 ATOM 1500 C C . ALA A 1 190 ? 40.176 15.954 143.407 1.00 13.13 ? 269 ALA N C 1 ATOM 1501 O O . ALA A 1 190 ? 41.367 16.307 143.499 1.00 14.63 ? 269 ALA N O 1 ATOM 1502 C CB . ALA A 1 190 ? 39.593 14.265 145.115 1.00 14.06 ? 269 ALA N CB 1 ATOM 1503 N N . GLY A 1 191 ? 39.220 16.814 143.071 1.00 11.98 ? 270 GLY N N 1 ATOM 1504 C CA . GLY A 1 191 ? 39.510 18.223 142.897 1.00 13.57 ? 270 GLY N CA 1 ATOM 1505 C C . GLY A 1 191 ? 38.931 18.713 141.591 1.00 10.49 ? 270 GLY N C 1 ATOM 1506 O O . GLY A 1 191 ? 38.049 18.017 141.074 1.00 9.00 ? 270 GLY N O 1 ATOM 1507 N N . THR A 1 192 ? 39.359 19.881 141.093 1.00 10.78 ? 271 THR N N 1 ATOM 1508 C CA . THR A 1 192 ? 38.804 20.493 139.900 1.00 9.87 ? 271 THR N CA 1 ATOM 1509 C C . THR A 1 192 ? 39.599 20.044 138.694 1.00 9.86 ? 271 THR N C 1 ATOM 1510 O O . THR A 1 192 ? 39.266 20.483 137.595 1.00 11.78 ? 271 THR N O 1 ATOM 1511 C CB . THR A 1 192 ? 38.825 22.068 140.030 1.00 8.12 ? 271 THR N CB 1 ATOM 1512 O OG1 . THR A 1 192 ? 39.919 22.426 140.843 1.00 8.57 ? 271 THR N OG1 1 ATOM 1513 C CG2 . THR A 1 192 ? 37.602 22.633 140.721 1.00 7.47 ? 271 THR N CG2 1 ATOM 1514 N N . ALA A 1 193 ? 40.647 19.210 138.795 1.00 9.22 ? 272 ALA N N 1 ATOM 1515 C CA . ALA A 1 193 ? 41.366 18.897 137.571 1.00 11.41 ? 272 ALA N CA 1 ATOM 1516 C C . ALA A 1 193 ? 40.546 18.026 136.651 1.00 11.95 ? 272 ALA N C 1 ATOM 1517 O O . ALA A 1 193 ? 39.664 17.319 137.134 1.00 13.75 ? 272 ALA N O 1 ATOM 1518 C CB . ALA A 1 193 ? 42.638 18.170 137.867 1.00 12.97 ? 272 ALA N CB 1 ATOM 1519 N N . LYS A 1 194 ? 40.810 17.996 135.357 1.00 13.85 ? 273 LYS N N 1 ATOM 1520 C CA . LYS A 1 194 ? 39.953 17.209 134.466 1.00 16.77 ? 273 LYS N CA 1 ATOM 1521 C C . LYS A 1 194 ? 40.613 15.988 133.851 1.00 17.49 ? 273 LYS N C 1 ATOM 1522 O O . LYS A 1 194 ? 39.919 15.134 133.292 1.00 19.61 ? 273 LYS N O 1 ATOM 1523 C CB . LYS A 1 194 ? 39.366 18.052 133.291 1.00 16.33 ? 273 LYS N CB 1 ATOM 1524 C CG . LYS A 1 194 ? 37.859 18.289 133.456 1.00 19.36 ? 273 LYS N CG 1 ATOM 1525 C CD . LYS A 1 194 ? 37.660 19.152 134.706 1.00 22.72 ? 273 LYS N CD 1 ATOM 1526 C CE . LYS A 1 194 ? 36.251 19.371 135.309 1.00 23.67 ? 273 LYS N CE 1 ATOM 1527 N NZ . LYS A 1 194 ? 36.266 20.559 136.157 1.00 23.16 ? 273 LYS N NZ 1 ATOM 1528 N N . HIS A 1 195 ? 41.929 15.828 133.915 1.00 18.17 ? 274 HIS N N 1 ATOM 1529 C CA . HIS A 1 195 ? 42.600 14.687 133.325 1.00 17.02 ? 274 HIS N CA 1 ATOM 1530 C C . HIS A 1 195 ? 44.008 14.787 133.877 1.00 15.55 ? 274 HIS N C 1 ATOM 1531 O O . HIS A 1 195 ? 44.471 15.916 134.092 1.00 16.73 ? 274 HIS N O 1 ATOM 1532 C CB . HIS A 1 195 ? 42.604 14.810 131.808 1.00 16.61 ? 274 HIS N CB 1 ATOM 1533 C CG . HIS A 1 195 ? 43.129 13.569 131.075 1.00 17.53 ? 274 HIS N CG 1 ATOM 1534 N ND1 . HIS A 1 195 ? 44.284 13.401 130.420 1.00 17.57 ? 274 HIS N ND1 1 ATOM 1535 C CD2 . HIS A 1 195 ? 42.450 12.370 131.019 1.00 18.22 ? 274 HIS N CD2 1 ATOM 1536 C CE1 . HIS A 1 195 ? 44.307 12.166 129.986 1.00 19.88 ? 274 HIS N CE1 1 ATOM 1537 N NE2 . HIS A 1 195 ? 43.207 11.554 130.349 1.00 20.04 ? 274 HIS N NE2 1 ATOM 1538 N N . ILE A 1 196 ? 44.678 13.679 134.164 1.00 11.94 ? 275 ILE N N 1 ATOM 1539 C CA . ILE A 1 196 ? 46.008 13.734 134.729 1.00 11.85 ? 275 ILE N CA 1 ATOM 1540 C C . ILE A 1 196 ? 47.030 12.857 133.990 1.00 10.23 ? 275 ILE N C 1 ATOM 1541 O O . ILE A 1 196 ? 46.872 11.648 133.784 1.00 9.57 ? 275 ILE N O 1 ATOM 1542 C CB . ILE A 1 196 ? 45.858 13.338 136.247 1.00 12.70 ? 275 ILE N CB 1 ATOM 1543 C CG1 . ILE A 1 196 ? 45.308 14.553 136.999 1.00 13.13 ? 275 ILE N CG1 1 ATOM 1544 C CG2 . ILE A 1 196 ? 47.194 12.903 136.888 1.00 11.88 ? 275 ILE N CG2 1 ATOM 1545 C CD1 . ILE A 1 196 ? 46.174 15.834 136.988 1.00 13.15 ? 275 ILE N CD1 1 ATOM 1546 N N . GLU A 1 197 ? 48.123 13.427 133.535 1.00 9.83 ? 276 GLU N N 1 ATOM 1547 C CA . GLU A 1 197 ? 49.190 12.627 132.981 1.00 11.11 ? 276 GLU N CA 1 ATOM 1548 C C . GLU A 1 197 ? 50.517 13.170 133.519 1.00 12.69 ? 276 GLU N C 1 ATOM 1549 O O . GLU A 1 197 ? 50.573 14.358 133.854 1.00 15.75 ? 276 GLU N O 1 ATOM 1550 C CB . GLU A 1 197 ? 49.196 12.752 131.475 1.00 12.71 ? 276 GLU N CB 1 ATOM 1551 C CG . GLU A 1 197 ? 47.895 12.593 130.704 1.00 18.65 ? 276 GLU N CG 1 ATOM 1552 C CD . GLU A 1 197 ? 47.800 11.291 129.942 1.00 19.40 ? 276 GLU N CD 1 ATOM 1553 O OE1 . GLU A 1 197 ? 48.652 11.012 129.109 1.00 19.22 ? 276 GLU N OE1 1 ATOM 1554 O OE2 . GLU A 1 197 ? 46.864 10.545 130.180 1.00 22.13 ? 276 GLU N OE2 1 ATOM 1555 N N . GLU A 1 198 ? 51.560 12.339 133.683 1.00 8.72 ? 277 GLU N N 1 ATOM 1556 C CA . GLU A 1 198 ? 52.958 12.719 133.871 1.00 5.75 ? 277 GLU N CA 1 ATOM 1557 C C . GLU A 1 198 ? 53.220 13.857 134.813 1.00 6.38 ? 277 GLU N C 1 ATOM 1558 O O . GLU A 1 198 ? 53.547 14.987 134.427 1.00 7.96 ? 277 GLU N O 1 ATOM 1559 C CB . GLU A 1 198 ? 53.528 13.058 132.527 1.00 4.26 ? 277 GLU N CB 1 ATOM 1560 C CG . GLU A 1 198 ? 53.538 11.944 131.506 1.00 5.73 ? 277 GLU N CG 1 ATOM 1561 C CD . GLU A 1 198 ? 53.527 12.391 130.052 1.00 7.83 ? 277 GLU N CD 1 ATOM 1562 O OE1 . GLU A 1 198 ? 53.337 13.562 129.780 1.00 8.31 ? 277 GLU N OE1 1 ATOM 1563 O OE2 . GLU A 1 198 ? 53.685 11.542 129.181 1.00 8.09 ? 277 GLU N OE2 1 ATOM 1564 N N . CYS A 1 199 ? 52.931 13.580 136.047 1.00 5.28 ? 278 CYS N N 1 ATOM 1565 C CA . CYS A 1 199 ? 53.069 14.641 137.005 1.00 5.85 ? 278 CYS N CA 1 ATOM 1566 C C . CYS A 1 199 ? 54.493 14.895 137.438 1.00 6.58 ? 278 CYS N C 1 ATOM 1567 O O . CYS A 1 199 ? 55.115 13.980 137.946 1.00 7.39 ? 278 CYS N O 1 ATOM 1568 C CB . CYS A 1 199 ? 52.168 14.326 138.215 1.00 5.60 ? 278 CYS N CB 1 ATOM 1569 S SG . CYS A 1 199 ? 50.437 14.401 137.899 1.00 2.00 ? 278 CYS N SG 1 ATOM 1570 N N . SER A 1 200 ? 55.019 16.106 137.274 1.00 4.82 ? 279 SER N N 1 ATOM 1571 C CA . SER A 1 200 ? 56.323 16.489 137.755 1.00 3.39 ? 279 SER N CA 1 ATOM 1572 C C . SER A 1 200 ? 56.164 16.874 139.203 1.00 2.02 ? 279 SER N C 1 ATOM 1573 O O . SER A 1 200 ? 55.366 17.748 139.481 1.00 3.60 ? 279 SER N O 1 ATOM 1574 C CB . SER A 1 200 ? 56.729 17.615 136.869 1.00 4.26 ? 279 SER N CB 1 ATOM 1575 O OG . SER A 1 200 ? 57.238 17.141 135.619 1.00 7.37 ? 279 SER N OG 1 ATOM 1576 N N . CYS A 1 201 ? 56.834 16.334 140.200 1.00 3.37 ? 280 CYS N N 1 ATOM 1577 C CA . CYS A 1 201 ? 56.557 16.678 141.594 1.00 2.22 ? 280 CYS N CA 1 ATOM 1578 C C . CYS A 1 201 ? 57.811 17.093 142.330 1.00 2.37 ? 280 CYS N C 1 ATOM 1579 O O . CYS A 1 201 ? 58.907 16.613 142.039 1.00 3.84 ? 280 CYS N O 1 ATOM 1580 C CB . CYS A 1 201 ? 56.003 15.527 142.443 1.00 3.34 ? 280 CYS N CB 1 ATOM 1581 S SG . CYS A 1 201 ? 54.547 14.631 141.871 1.00 5.40 ? 280 CYS N SG 1 ATOM 1582 N N . TYR A 1 202 ? 57.741 17.983 143.291 1.00 2.12 ? 281 TYR N N 1 ATOM 1583 C CA . TYR A 1 202 ? 58.885 18.306 144.128 1.00 3.95 ? 281 TYR N CA 1 ATOM 1584 C C . TYR A 1 202 ? 58.340 18.338 145.562 1.00 3.84 ? 281 TYR N C 1 ATOM 1585 O O . TYR A 1 202 ? 57.109 18.220 145.673 1.00 4.53 ? 281 TYR N O 1 ATOM 1586 C CB . TYR A 1 202 ? 59.438 19.639 143.668 1.00 4.20 ? 281 TYR N CB 1 ATOM 1587 C CG . TYR A 1 202 ? 58.470 20.806 143.827 1.00 3.59 ? 281 TYR N CG 1 ATOM 1588 C CD1 . TYR A 1 202 ? 57.525 21.059 142.864 1.00 2.41 ? 281 TYR N CD1 1 ATOM 1589 C CD2 . TYR A 1 202 ? 58.558 21.621 144.923 1.00 3.76 ? 281 TYR N CD2 1 ATOM 1590 C CE1 . TYR A 1 202 ? 56.687 22.123 142.968 1.00 2.00 ? 281 TYR N CE1 1 ATOM 1591 C CE2 . TYR A 1 202 ? 57.704 22.694 145.039 1.00 4.70 ? 281 TYR N CE2 1 ATOM 1592 C CZ . TYR A 1 202 ? 56.781 22.934 144.060 1.00 3.09 ? 281 TYR N CZ 1 ATOM 1593 O OH . TYR A 1 202 ? 55.932 24.023 144.159 1.00 2.84 ? 281 TYR N OH 1 ATOM 1594 N N . GLY A 1 203 ? 59.100 18.442 146.662 1.00 4.81 ? 282 GLY N N 1 ATOM 1595 C CA . GLY A 1 203 ? 58.493 18.516 147.984 1.00 8.04 ? 282 GLY N CA 1 ATOM 1596 C C . GLY A 1 203 ? 59.154 19.535 148.933 1.00 9.19 ? 282 GLY N C 1 ATOM 1597 O O . GLY A 1 203 ? 60.399 19.647 149.013 1.00 9.14 ? 282 GLY N O 1 ATOM 1598 N N . GLU A 1 204 ? 58.336 20.314 149.673 1.00 10.12 ? 283 GLU N N 1 ATOM 1599 C CA . GLU A 1 204 ? 58.834 21.283 150.666 1.00 10.90 ? 283 GLU N CA 1 ATOM 1600 C C . GLU A 1 204 ? 57.776 21.470 151.734 1.00 10.30 ? 283 GLU N C 1 ATOM 1601 O O . GLU A 1 204 ? 56.564 21.282 151.515 1.00 9.07 ? 283 GLU N O 1 ATOM 1602 C CB . GLU A 1 204 ? 59.140 22.661 150.054 1.00 10.02 ? 283 GLU N CB 1 ATOM 1603 C CG . GLU A 1 204 ? 58.085 23.208 149.096 1.00 13.32 ? 283 GLU N CG 1 ATOM 1604 C CD . GLU A 1 204 ? 57.084 24.236 149.613 1.00 16.36 ? 283 GLU N CD 1 ATOM 1605 O OE1 . GLU A 1 204 ? 57.495 25.397 149.745 1.00 16.82 ? 283 GLU N OE1 1 ATOM 1606 O OE2 . GLU A 1 204 ? 55.915 23.894 149.828 1.00 17.02 ? 283 GLU N OE2 1 ATOM 1607 N N . ARG A 1 205 ? 58.365 21.691 152.907 1.00 10.90 ? 284 ARG N N 1 ATOM 1608 C CA . ARG A 1 205 ? 57.639 21.975 154.119 1.00 13.75 ? 284 ARG N CA 1 ATOM 1609 C C . ARG A 1 205 ? 56.564 20.928 154.267 1.00 12.79 ? 284 ARG N C 1 ATOM 1610 O O . ARG A 1 205 ? 55.386 21.246 154.195 1.00 15.74 ? 284 ARG N O 1 ATOM 1611 C CB . ARG A 1 205 ? 56.991 23.402 154.074 1.00 14.80 ? 284 ARG N CB 1 ATOM 1612 C CG . ARG A 1 205 ? 57.835 24.688 154.128 1.00 16.57 ? 284 ARG N CG 1 ATOM 1613 C CD . ARG A 1 205 ? 57.485 25.542 152.903 1.00 20.55 ? 284 ARG N CD 1 ATOM 1614 N NE . ARG A 1 205 ? 56.843 26.831 153.155 1.00 27.70 ? 284 ARG N NE 1 ATOM 1615 C CZ . ARG A 1 205 ? 56.052 27.513 152.281 1.00 32.89 ? 284 ARG N CZ 1 ATOM 1616 N NH1 . ARG A 1 205 ? 55.747 27.159 151.025 1.00 36.67 ? 284 ARG N NH1 1 ATOM 1617 N NH2 . ARG A 1 205 ? 55.544 28.689 152.667 1.00 35.22 ? 284 ARG N NH2 1 ATOM 1618 N N . ALA A 1 206 ? 56.946 19.673 154.448 1.00 14.65 ? 285 ALA N N 1 ATOM 1619 C CA . ALA A 1 206 ? 56.022 18.559 154.556 1.00 13.21 ? 285 ALA N CA 1 ATOM 1620 C C . ALA A 1 206 ? 54.848 18.396 153.590 1.00 14.21 ? 285 ALA N C 1 ATOM 1621 O O . ALA A 1 206 ? 53.869 17.724 153.921 1.00 16.23 ? 285 ALA N O 1 ATOM 1622 C CB . ALA A 1 206 ? 55.486 18.562 155.974 1.00 13.50 ? 285 ALA N CB 1 ATOM 1623 N N . GLU A 1 207 ? 54.955 18.900 152.362 1.00 16.14 ? 286 GLU N N 1 ATOM 1624 C CA . GLU A 1 207 ? 53.853 18.853 151.411 1.00 17.48 ? 286 GLU N CA 1 ATOM 1625 C C . GLU A 1 207 ? 54.418 18.548 150.019 1.00 16.20 ? 286 GLU N C 1 ATOM 1626 O O . GLU A 1 207 ? 55.598 18.841 149.733 1.00 17.55 ? 286 GLU N O 1 ATOM 1627 C CB . GLU A 1 207 ? 53.171 20.229 151.519 1.00 20.73 ? 286 GLU N CB 1 ATOM 1628 C CG . GLU A 1 207 ? 51.743 20.502 151.079 1.00 25.66 ? 286 GLU N CG 1 ATOM 1629 C CD . GLU A 1 207 ? 51.567 21.830 150.303 1.00 28.95 ? 286 GLU N CD 1 ATOM 1630 O OE1 . GLU A 1 207 ? 52.035 22.912 150.740 1.00 29.98 ? 286 GLU N OE1 1 ATOM 1631 O OE2 . GLU A 1 207 ? 50.954 21.762 149.228 1.00 32.64 ? 286 GLU N OE2 1 ATOM 1632 N N . ILE A 1 208 ? 53.623 17.917 149.142 1.00 13.34 ? 287 ILE N N 1 ATOM 1633 C CA . ILE A 1 208 ? 54.113 17.542 147.826 1.00 11.36 ? 287 ILE N CA 1 ATOM 1634 C C . ILE A 1 208 ? 53.255 18.172 146.745 1.00 9.69 ? 287 ILE N C 1 ATOM 1635 O O . ILE A 1 208 ? 52.028 18.028 146.805 1.00 7.93 ? 287 ILE N O 1 ATOM 1636 C CB . ILE A 1 208 ? 54.133 15.998 147.789 1.00 11.14 ? 287 ILE N CB 1 ATOM 1637 C CG1 . ILE A 1 208 ? 55.498 15.546 148.287 1.00 8.80 ? 287 ILE N CG1 1 ATOM 1638 C CG2 . ILE A 1 208 ? 53.836 15.451 146.391 1.00 10.67 ? 287 ILE N CG2 1 ATOM 1639 C CD1 . ILE A 1 208 ? 55.462 14.132 148.850 1.00 7.39 ? 287 ILE N CD1 1 ATOM 1640 N N . THR A 1 209 ? 53.961 18.897 145.839 1.00 8.34 ? 288 THR N N 1 ATOM 1641 C CA . THR A 1 209 ? 53.370 19.588 144.693 1.00 6.78 ? 288 THR N CA 1 ATOM 1642 C C . THR A 1 209 ? 53.628 18.912 143.371 1.00 7.98 ? 288 THR N C 1 ATOM 1643 O O . THR A 1 209 ? 54.794 18.654 143.060 1.00 11.03 ? 288 THR N O 1 ATOM 1644 C CB . THR A 1 209 ? 53.907 20.982 144.477 1.00 7.05 ? 288 THR N CB 1 ATOM 1645 O OG1 . THR A 1 209 ? 54.029 21.675 145.719 1.00 11.48 ? 288 THR N OG1 1 ATOM 1646 C CG2 . THR A 1 209 ? 52.960 21.731 143.597 1.00 4.62 ? 288 THR N CG2 1 ATOM 1647 N N . CYS A 1 210 ? 52.599 18.703 142.553 1.00 6.92 ? 289 CYS N N 1 ATOM 1648 C CA . CYS A 1 210 ? 52.767 17.989 141.303 1.00 5.61 ? 289 CYS N CA 1 ATOM 1649 C C . CYS A 1 210 ? 52.093 18.786 140.193 1.00 7.24 ? 289 CYS N C 1 ATOM 1650 O O . CYS A 1 210 ? 50.939 19.185 140.367 1.00 8.85 ? 289 CYS N O 1 ATOM 1651 C CB . CYS A 1 210 ? 52.158 16.606 141.430 1.00 4.81 ? 289 CYS N CB 1 ATOM 1652 S SG . CYS A 1 210 ? 52.916 15.528 142.669 1.00 3.87 ? 289 CYS N SG 1 ATOM 1653 N N . THR A 1 211 ? 52.832 19.175 139.146 1.00 7.11 ? 290 THR N N 1 ATOM 1654 C CA . THR A 1 211 ? 52.313 19.898 137.989 1.00 4.73 ? 290 THR N CA 1 ATOM 1655 C C . THR A 1 211 ? 52.224 18.761 137.015 1.00 5.14 ? 290 THR N C 1 ATOM 1656 O O . THR A 1 211 ? 53.222 18.052 136.880 1.00 5.86 ? 290 THR N O 1 ATOM 1657 C CB . THR A 1 211 ? 53.233 20.872 137.294 1.00 6.77 ? 290 THR N CB 1 ATOM 1658 O OG1 . THR A 1 211 ? 53.868 21.660 138.258 1.00 11.30 ? 290 THR N OG1 1 ATOM 1659 C CG2 . THR A 1 211 ? 52.455 21.778 136.398 1.00 6.81 ? 290 THR N CG2 1 ATOM 1660 N N . CYS A 1 212 ? 51.059 18.589 136.392 1.00 5.34 ? 291 CYS N N 1 ATOM 1661 C CA . CYS A 1 212 ? 50.826 17.433 135.574 1.00 3.24 ? 291 CYS N CA 1 ATOM 1662 C C . CYS A 1 212 ? 50.488 17.920 134.218 1.00 4.52 ? 291 CYS N C 1 ATOM 1663 O O . CYS A 1 212 ? 50.809 19.071 133.880 1.00 3.38 ? 291 CYS N O 1 ATOM 1664 C CB . CYS A 1 212 ? 49.706 16.669 136.241 1.00 2.95 ? 291 CYS N CB 1 ATOM 1665 S SG . CYS A 1 212 ? 50.165 16.401 137.926 1.00 4.43 ? 291 CYS N SG 1 ATOM 1666 N N . ARG A 1 213 ? 49.789 17.062 133.492 1.00 4.88 ? 292 ARG N N 1 ATOM 1667 C CA . ARG A 1 213 ? 49.471 17.286 132.107 1.00 6.97 ? 292 ARG N CA 1 ATOM 1668 C C . ARG A 1 213 ? 48.005 16.994 131.823 1.00 9.75 ? 292 ARG N C 1 ATOM 1669 O O . ARG A 1 213 ? 47.493 15.894 132.135 1.00 11.80 ? 292 ARG N O 1 ATOM 1670 C CB . ARG A 1 213 ? 50.367 16.369 131.335 1.00 5.25 ? 292 ARG N CB 1 ATOM 1671 C CG . ARG A 1 213 ? 50.248 16.536 129.882 1.00 4.29 ? 292 ARG N CG 1 ATOM 1672 C CD . ARG A 1 213 ? 50.510 15.182 129.335 1.00 4.92 ? 292 ARG N CD 1 ATOM 1673 N NE . ARG A 1 213 ? 50.530 15.306 127.912 1.00 8.18 ? 292 ARG N NE 1 ATOM 1674 C CZ . ARG A 1 213 ? 51.303 14.541 127.175 1.00 8.52 ? 292 ARG N CZ 1 ATOM 1675 N NH1 . ARG A 1 213 ? 51.865 13.428 127.620 1.00 10.06 ? 292 ARG N NH1 1 ATOM 1676 N NH2 . ARG A 1 213 ? 51.375 14.811 125.890 1.00 9.12 ? 292 ARG N NH2 1 ATOM 1677 N N . ASP A 1 214 ? 47.331 18.001 131.262 1.00 13.10 ? 293 ASP N N 1 ATOM 1678 C CA . ASP A 1 214 ? 46.005 17.777 130.786 1.00 14.04 ? 293 ASP N CA 1 ATOM 1679 C C . ASP A 1 214 ? 46.008 17.682 129.255 1.00 15.42 ? 293 ASP N C 1 ATOM 1680 O O . ASP A 1 214 ? 46.205 18.556 128.331 1.00 18.14 ? 293 ASP N O 1 ATOM 1681 C CB . ASP A 1 214 ? 45.118 18.873 131.268 1.00 15.43 ? 293 ASP N CB 1 ATOM 1682 C CG . ASP A 1 214 ? 43.600 18.697 131.087 1.00 17.44 ? 293 ASP N CG 1 ATOM 1683 O OD1 . ASP A 1 214 ? 43.122 17.734 130.445 1.00 18.19 ? 293 ASP N OD1 1 ATOM 1684 O OD2 . ASP A 1 214 ? 42.888 19.582 131.601 1.00 16.81 ? 293 ASP N OD2 1 ATOM 1685 N N . ASN A 1 215 ? 45.727 16.391 129.092 1.00 13.14 ? 294 ASN N N 1 ATOM 1686 C CA . ASN A 1 215 ? 45.760 15.824 127.775 1.00 12.76 ? 294 ASN N CA 1 ATOM 1687 C C . ASN A 1 215 ? 44.471 15.960 127.069 1.00 12.96 ? 294 ASN N C 1 ATOM 1688 O O . ASN A 1 215 ? 44.502 16.237 125.887 1.00 11.96 ? 294 ASN N O 1 ATOM 1689 C CB . ASN A 1 215 ? 46.114 14.362 127.791 1.00 11.51 ? 294 ASN N CB 1 ATOM 1690 C CG . ASN A 1 215 ? 46.877 14.078 126.500 1.00 10.59 ? 294 ASN N CG 1 ATOM 1691 O OD1 . ASN A 1 215 ? 48.048 14.477 126.402 1.00 10.67 ? 294 ASN N OD1 1 ATOM 1692 N ND2 . ASN A 1 215 ? 46.265 13.474 125.479 1.00 9.39 ? 294 ASN N ND2 1 ATOM 1693 N N . TRP A 1 216 ? 43.363 15.948 127.782 1.00 12.91 ? 295 TRP N N 1 ATOM 1694 C CA . TRP A 1 216 ? 42.049 16.040 127.140 1.00 16.71 ? 295 TRP N CA 1 ATOM 1695 C C . TRP A 1 216 ? 41.763 17.423 126.586 1.00 18.12 ? 295 TRP N C 1 ATOM 1696 O O . TRP A 1 216 ? 41.598 17.550 125.385 1.00 17.82 ? 295 TRP N O 1 ATOM 1697 C CB . TRP A 1 216 ? 40.967 15.631 128.173 1.00 19.54 ? 295 TRP N CB 1 ATOM 1698 C CG . TRP A 1 216 ? 39.501 15.515 127.753 1.00 20.43 ? 295 TRP N CG 1 ATOM 1699 C CD1 . TRP A 1 216 ? 39.110 15.315 126.457 1.00 21.42 ? 295 TRP N CD1 1 ATOM 1700 C CD2 . TRP A 1 216 ? 38.433 15.593 128.599 1.00 22.45 ? 295 TRP N CD2 1 ATOM 1701 N NE1 . TRP A 1 216 ? 37.799 15.274 126.488 1.00 20.01 ? 295 TRP N NE1 1 ATOM 1702 C CE2 . TRP A 1 216 ? 37.372 15.436 127.746 1.00 21.64 ? 295 TRP N CE2 1 ATOM 1703 C CE3 . TRP A 1 216 ? 38.206 15.776 129.938 1.00 25.11 ? 295 TRP N CE3 1 ATOM 1704 C CZ2 . TRP A 1 216 ? 36.079 15.455 128.211 1.00 21.84 ? 295 TRP N CZ2 1 ATOM 1705 C CZ3 . TRP A 1 216 ? 36.906 15.797 130.409 1.00 24.96 ? 295 TRP N CZ3 1 ATOM 1706 C CH2 . TRP A 1 216 ? 35.847 15.640 129.555 1.00 22.50 ? 295 TRP N CH2 1 ATOM 1707 N N . GLN A 1 217 ? 41.693 18.446 127.454 1.00 20.17 ? 296 GLN N N 1 ATOM 1708 C CA . GLN A 1 217 ? 41.396 19.820 127.065 1.00 20.65 ? 296 GLN N CA 1 ATOM 1709 C C . GLN A 1 217 ? 42.417 20.900 127.484 1.00 21.22 ? 296 GLN N C 1 ATOM 1710 O O . GLN A 1 217 ? 42.490 22.011 126.940 1.00 22.29 ? 296 GLN N O 1 ATOM 1711 C CB . GLN A 1 217 ? 40.035 20.147 127.635 1.00 23.11 ? 296 GLN N CB 1 ATOM 1712 C CG . GLN A 1 217 ? 38.953 19.091 127.335 1.00 23.51 ? 296 GLN N CG 1 ATOM 1713 C CD . GLN A 1 217 ? 37.786 19.116 128.322 1.00 24.07 ? 296 GLN N CD 1 ATOM 1714 O OE1 . GLN A 1 217 ? 36.615 19.154 127.952 1.00 26.40 ? 296 GLN N OE1 1 ATOM 1715 N NE2 . GLN A 1 217 ? 38.038 19.060 129.628 1.00 22.31 ? 296 GLN N NE2 1 ATOM 1716 N N . GLY A 1 218 ? 43.321 20.582 128.408 1.00 19.25 ? 297 GLY N N 1 ATOM 1717 C CA . GLY A 1 218 ? 44.210 21.580 128.995 1.00 16.28 ? 297 GLY N CA 1 ATOM 1718 C C . GLY A 1 218 ? 45.480 21.876 128.204 1.00 15.57 ? 297 GLY N C 1 ATOM 1719 O O . GLY A 1 218 ? 46.135 21.014 127.451 1.00 20.37 ? 297 GLY N O 1 ATOM 1720 N N . SER A 1 219 ? 45.464 23.224 128.287 1.00 12.92 ? 298 SER N N 1 ATOM 1721 C CA . SER A 1 219 ? 46.543 24.091 127.845 1.00 10.83 ? 298 SER N CA 1 ATOM 1722 C C . SER A 1 219 ? 47.114 24.842 129.048 1.00 8.70 ? 298 SER N C 1 ATOM 1723 O O . SER A 1 219 ? 48.235 25.356 129.021 1.00 10.42 ? 298 SER N O 1 ATOM 1724 C CB . SER A 1 219 ? 46.055 25.090 126.784 1.00 11.61 ? 298 SER N CB 1 ATOM 1725 O OG . SER A 1 219 ? 45.400 24.566 125.614 1.00 9.57 ? 298 SER N OG 1 ATOM 1726 N N . ASN A 1 220 ? 46.357 24.930 130.142 1.00 6.38 ? 299 ASN N N 1 ATOM 1727 C CA . ASN A 1 220 ? 46.947 25.363 131.401 1.00 8.46 ? 299 ASN N CA 1 ATOM 1728 C C . ASN A 1 220 ? 47.127 24.018 132.058 1.00 7.98 ? 299 ASN N C 1 ATOM 1729 O O . ASN A 1 220 ? 46.509 22.999 131.674 1.00 6.40 ? 299 ASN N O 1 ATOM 1730 C CB . ASN A 1 220 ? 46.042 26.248 132.342 1.00 11.23 ? 299 ASN N CB 1 ATOM 1731 C CG . ASN A 1 220 ? 44.559 25.906 132.535 1.00 13.74 ? 299 ASN N CG 1 ATOM 1732 O OD1 . ASN A 1 220 ? 43.964 25.014 131.879 1.00 13.55 ? 299 ASN N OD1 1 ATOM 1733 N ND2 . ASN A 1 220 ? 43.940 26.686 133.435 1.00 14.73 ? 299 ASN N ND2 1 ATOM 1734 N N . ARG A 1 221 ? 48.046 23.983 132.992 1.00 10.25 ? 300 ARG N N 1 ATOM 1735 C CA . ARG A 1 221 ? 48.414 22.754 133.648 1.00 9.45 ? 300 ARG N CA 1 ATOM 1736 C C . ARG A 1 221 ? 47.662 22.610 134.960 1.00 9.55 ? 300 ARG N C 1 ATOM 1737 O O . ARG A 1 221 ? 47.423 23.632 135.638 1.00 9.54 ? 300 ARG N O 1 ATOM 1738 C CB . ARG A 1 221 ? 49.895 22.736 133.902 1.00 9.51 ? 300 ARG N CB 1 ATOM 1739 C CG . ARG A 1 221 ? 50.673 23.175 132.673 1.00 10.20 ? 300 ARG N CG 1 ATOM 1740 C CD . ARG A 1 221 ? 52.068 22.629 132.761 1.00 10.04 ? 300 ARG N CD 1 ATOM 1741 N NE . ARG A 1 221 ? 52.048 21.293 132.191 1.00 7.48 ? 300 ARG N NE 1 ATOM 1742 C CZ . ARG A 1 221 ? 52.809 21.015 131.149 1.00 7.11 ? 300 ARG N CZ 1 ATOM 1743 N NH1 . ARG A 1 221 ? 53.740 21.842 130.713 1.00 7.60 ? 300 ARG N NH1 1 ATOM 1744 N NH2 . ARG A 1 221 ? 52.680 19.871 130.536 1.00 7.72 ? 300 ARG N NH2 1 ATOM 1745 N N . PRO A 1 222 ? 47.218 21.359 135.268 1.00 8.83 ? 301 PRO N N 1 ATOM 1746 C CA . PRO A 1 222 ? 46.600 20.977 136.512 1.00 7.05 ? 301 PRO N CA 1 ATOM 1747 C C . PRO A 1 222 ? 47.650 20.619 137.572 1.00 6.96 ? 301 PRO N C 1 ATOM 1748 O O . PRO A 1 222 ? 48.664 19.986 137.274 1.00 9.59 ? 301 PRO N O 1 ATOM 1749 C CB . PRO A 1 222 ? 45.697 19.846 136.085 1.00 8.38 ? 301 PRO N CB 1 ATOM 1750 C CG . PRO A 1 222 ? 46.533 19.084 135.126 1.00 8.25 ? 301 PRO N CG 1 ATOM 1751 C CD . PRO A 1 222 ? 47.328 20.169 134.419 1.00 9.55 ? 301 PRO N CD 1 ATOM 1752 N N . VAL A 1 223 ? 47.378 20.929 138.827 1.00 7.07 ? 302 VAL N N 1 ATOM 1753 C CA . VAL A 1 223 ? 48.288 20.837 139.931 1.00 4.98 ? 302 VAL N CA 1 ATOM 1754 C C . VAL A 1 223 ? 47.670 20.001 141.034 1.00 5.79 ? 302 VAL N C 1 ATOM 1755 O O . VAL A 1 223 ? 46.571 20.323 141.490 1.00 3.02 ? 302 VAL N O 1 ATOM 1756 C CB . VAL A 1 223 ? 48.605 22.308 140.375 1.00 3.23 ? 302 VAL N CB 1 ATOM 1757 C CG1 . VAL A 1 223 ? 49.462 22.397 141.626 1.00 2.00 ? 302 VAL N CG1 1 ATOM 1758 C CG2 . VAL A 1 223 ? 49.419 22.949 139.268 1.00 3.77 ? 302 VAL N CG2 1 ATOM 1759 N N . ILE A 1 224 ? 48.340 18.939 141.502 1.00 10.20 ? 303 ILE N N 1 ATOM 1760 C CA . ILE A 1 224 ? 47.911 18.120 142.638 1.00 11.00 ? 303 ILE N CA 1 ATOM 1761 C C . ILE A 1 224 ? 48.801 18.453 143.841 1.00 12.37 ? 303 ILE N C 1 ATOM 1762 O O . ILE A 1 224 ? 50.031 18.418 143.660 1.00 13.34 ? 303 ILE N O 1 ATOM 1763 C CB . ILE A 1 224 ? 48.048 16.637 142.276 1.00 8.09 ? 303 ILE N CB 1 ATOM 1764 C CG1 . ILE A 1 224 ? 47.137 16.255 141.168 1.00 5.48 ? 303 ILE N CG1 1 ATOM 1765 C CG2 . ILE A 1 224 ? 47.774 15.825 143.525 1.00 7.63 ? 303 ILE N CG2 1 ATOM 1766 C CD1 . ILE A 1 224 ? 47.405 14.800 140.814 1.00 5.25 ? 303 ILE N CD1 1 ATOM 1767 N N . ARG A 1 225 ? 48.272 18.768 145.031 1.00 14.40 ? 304 ARG N N 1 ATOM 1768 C CA . ARG A 1 225 ? 49.095 19.024 146.229 1.00 19.75 ? 304 ARG N CA 1 ATOM 1769 C C . ARG A 1 225 ? 48.602 17.930 147.171 1.00 16.81 ? 304 ARG N C 1 ATOM 1770 O O . ARG A 1 225 ? 47.381 17.779 147.383 1.00 14.27 ? 304 ARG N O 1 ATOM 1771 C CB . ARG A 1 225 ? 48.849 20.358 146.965 1.00 24.50 ? 304 ARG N CB 1 ATOM 1772 C CG . ARG A 1 225 ? 48.316 21.558 146.167 1.00 32.79 ? 304 ARG N CG 1 ATOM 1773 C CD . ARG A 1 225 ? 48.626 22.910 146.835 1.00 39.78 ? 304 ARG N CD 1 ATOM 1774 N NE . ARG A 1 225 ? 50.063 23.210 146.770 1.00 45.48 ? 304 ARG N NE 1 ATOM 1775 C CZ . ARG A 1 225 ? 50.599 24.431 146.914 1.00 49.66 ? 304 ARG N CZ 1 ATOM 1776 N NH1 . ARG A 1 225 ? 49.851 25.508 147.171 1.00 51.74 ? 304 ARG N NH1 1 ATOM 1777 N NH2 . ARG A 1 225 ? 51.927 24.570 146.811 1.00 51.11 ? 304 ARG N NH2 1 ATOM 1778 N N . ILE A 1 226 ? 49.577 17.157 147.680 1.00 13.65 ? 305 ILE N N 1 ATOM 1779 C CA . ILE A 1 226 ? 49.373 15.917 148.406 1.00 9.92 ? 305 ILE N CA 1 ATOM 1780 C C . ILE A 1 226 ? 49.925 16.170 149.787 1.00 10.29 ? 305 ILE N C 1 ATOM 1781 O O . ILE A 1 226 ? 51.041 16.702 149.871 1.00 9.54 ? 305 ILE N O 1 ATOM 1782 C CB . ILE A 1 226 ? 50.155 14.768 147.672 1.00 9.04 ? 305 ILE N CB 1 ATOM 1783 C CG1 . ILE A 1 226 ? 49.580 14.501 146.312 1.00 6.97 ? 305 ILE N CG1 1 ATOM 1784 C CG2 . ILE A 1 226 ? 50.083 13.503 148.461 1.00 6.67 ? 305 ILE N CG2 1 ATOM 1785 C CD1 . ILE A 1 226 ? 50.381 13.549 145.400 1.00 6.10 ? 305 ILE N CD1 1 ATOM 1786 N N . ASP A 1 227 ? 49.159 15.906 150.860 1.00 14.20 ? 306 ASP N N 1 ATOM 1787 C CA . ASP A 1 227 ? 49.683 15.914 152.219 1.00 16.13 ? 306 ASP N CA 1 ATOM 1788 C C . ASP A 1 227 ? 50.156 14.481 152.440 1.00 15.52 ? 306 ASP N C 1 ATOM 1789 O O . ASP A 1 227 ? 49.303 13.589 152.578 1.00 13.79 ? 306 ASP N O 1 ATOM 1790 C CB . ASP A 1 227 ? 48.638 16.206 153.305 1.00 16.16 ? 306 ASP N CB 1 ATOM 1791 C CG . ASP A 1 227 ? 49.171 16.240 154.749 1.00 18.37 ? 306 ASP N CG 1 ATOM 1792 O OD1 . ASP A 1 227 ? 50.343 15.993 155.026 1.00 18.60 ? 306 ASP N OD1 1 ATOM 1793 O OD2 . ASP A 1 227 ? 48.387 16.541 155.639 1.00 20.99 ? 306 ASP N OD2 1 ATOM 1794 N N . PRO A 1 228 ? 51.498 14.260 152.533 1.00 15.82 ? 307 PRO N N 1 ATOM 1795 C CA . PRO A 1 228 ? 52.125 12.936 152.609 1.00 14.94 ? 307 PRO N CA 1 ATOM 1796 C C . PRO A 1 228 ? 51.858 12.331 153.970 1.00 16.43 ? 307 PRO N C 1 ATOM 1797 O O . PRO A 1 228 ? 51.644 11.115 154.087 1.00 17.67 ? 307 PRO N O 1 ATOM 1798 C CB . PRO A 1 228 ? 53.588 13.192 152.329 1.00 12.85 ? 307 PRO N CB 1 ATOM 1799 C CG . PRO A 1 228 ? 53.820 14.581 152.850 1.00 13.95 ? 307 PRO N CG 1 ATOM 1800 C CD . PRO A 1 228 ? 52.549 15.288 152.406 1.00 13.85 ? 307 PRO N CD 1 ATOM 1801 N N . VAL A 1 229 ? 51.759 13.234 154.969 1.00 16.54 ? 308 VAL N N 1 ATOM 1802 C CA . VAL A 1 229 ? 51.485 12.892 156.364 1.00 17.33 ? 308 VAL N CA 1 ATOM 1803 C C . VAL A 1 229 ? 50.068 12.416 156.562 1.00 16.33 ? 308 VAL N C 1 ATOM 1804 O O . VAL A 1 229 ? 49.889 11.347 157.137 1.00 18.27 ? 308 VAL N O 1 ATOM 1805 C CB . VAL A 1 229 ? 51.716 14.123 157.275 1.00 17.09 ? 308 VAL N CB 1 ATOM 1806 C CG1 . VAL A 1 229 ? 51.314 13.798 158.720 1.00 15.59 ? 308 VAL N CG1 1 ATOM 1807 C CG2 . VAL A 1 229 ? 53.170 14.602 157.064 1.00 16.86 ? 308 VAL N CG2 1 ATOM 1808 N N . ALA A 1 230 ? 49.084 13.212 156.106 1.00 14.49 ? 309 ALA N N 1 ATOM 1809 C CA . ALA A 1 230 ? 47.696 12.831 156.312 1.00 14.55 ? 309 ALA N CA 1 ATOM 1810 C C . ALA A 1 230 ? 47.117 11.916 155.249 1.00 13.17 ? 309 ALA N C 1 ATOM 1811 O O . ALA A 1 230 ? 46.047 11.324 155.399 1.00 13.86 ? 309 ALA N O 1 ATOM 1812 C CB . ALA A 1 230 ? 46.801 14.002 156.350 1.00 12.72 ? 309 ALA N CB 1 ATOM 1813 N N . MET A 1 231 ? 47.847 11.812 154.151 1.00 12.38 ? 310 MET N N 1 ATOM 1814 C CA . MET A 1 231 ? 47.522 10.969 153.027 1.00 9.13 ? 310 MET N CA 1 ATOM 1815 C C . MET A 1 231 ? 46.235 11.378 152.344 1.00 9.52 ? 310 MET N C 1 ATOM 1816 O O . MET A 1 231 ? 45.300 10.631 152.064 1.00 9.35 ? 310 MET N O 1 ATOM 1817 C CB . MET A 1 231 ? 47.517 9.474 153.495 1.00 8.45 ? 310 MET N CB 1 ATOM 1818 C CG . MET A 1 231 ? 48.922 8.875 153.667 1.00 9.97 ? 310 MET N CG 1 ATOM 1819 S SD . MET A 1 231 ? 48.892 7.128 154.185 1.00 13.59 ? 310 MET N SD 1 ATOM 1820 C CE . MET A 1 231 ? 49.958 7.350 155.583 1.00 13.05 ? 310 MET N CE 1 ATOM 1821 N N . THR A 1 232 ? 46.268 12.650 151.997 1.00 11.46 ? 311 THR N N 1 ATOM 1822 C CA . THR A 1 232 ? 45.170 13.241 151.260 1.00 10.33 ? 311 THR N CA 1 ATOM 1823 C C . THR A 1 232 ? 45.743 14.086 150.131 1.00 11.13 ? 311 THR N C 1 ATOM 1824 O O . THR A 1 232 ? 46.955 14.306 150.163 1.00 14.25 ? 311 THR N O 1 ATOM 1825 C CB . THR A 1 232 ? 44.374 14.092 152.204 1.00 10.38 ? 311 THR N CB 1 ATOM 1826 O OG1 . THR A 1 232 ? 45.327 14.982 152.794 1.00 16.29 ? 311 THR N OG1 1 ATOM 1827 C CG2 . THR A 1 232 ? 43.647 13.281 153.265 1.00 11.27 ? 311 THR N CG2 1 ATOM 1828 N N . HIS A 1 233 ? 44.987 14.536 149.119 1.00 10.71 ? 312 HIS N N 1 ATOM 1829 C CA . HIS A 1 233 ? 45.476 15.509 148.160 1.00 12.13 ? 312 HIS N CA 1 ATOM 1830 C C . HIS A 1 233 ? 44.316 16.382 147.688 1.00 14.02 ? 312 HIS N C 1 ATOM 1831 O O . HIS A 1 233 ? 43.185 16.140 148.130 1.00 12.36 ? 312 HIS N O 1 ATOM 1832 C CB . HIS A 1 233 ? 46.076 14.828 146.956 1.00 9.91 ? 312 HIS N CB 1 ATOM 1833 C CG . HIS A 1 233 ? 45.032 14.067 146.197 1.00 5.64 ? 312 HIS N CG 1 ATOM 1834 N ND1 . HIS A 1 233 ? 44.575 12.881 146.551 1.00 5.74 ? 312 HIS N ND1 1 ATOM 1835 C CD2 . HIS A 1 233 ? 44.334 14.540 145.116 1.00 4.37 ? 312 HIS N CD2 1 ATOM 1836 C CE1 . HIS A 1 233 ? 43.582 12.606 145.735 1.00 5.04 ? 312 HIS N CE1 1 ATOM 1837 N NE2 . HIS A 1 233 ? 43.457 13.614 144.884 1.00 4.11 ? 312 HIS N NE2 1 ATOM 1838 N N . THR A 1 234 ? 44.530 17.372 146.797 1.00 16.70 ? 313 THR N N 1 ATOM 1839 C CA . THR A 1 234 ? 43.472 18.158 146.132 1.00 17.47 ? 313 THR N CA 1 ATOM 1840 C C . THR A 1 234 ? 43.969 18.500 144.725 1.00 14.86 ? 313 THR N C 1 ATOM 1841 O O . THR A 1 234 ? 45.187 18.319 144.517 1.00 16.03 ? 313 THR N O 1 ATOM 1842 C CB . THR A 1 234 ? 43.167 19.495 146.842 1.00 20.30 ? 313 THR N CB 1 ATOM 1843 O OG1 . THR A 1 234 ? 44.361 20.256 146.848 1.00 25.16 ? 313 THR N OG1 1 ATOM 1844 C CG2 . THR A 1 234 ? 42.668 19.295 148.266 1.00 23.97 ? 313 THR N CG2 1 ATOM 1845 N N . SER A 1 235 ? 43.175 18.955 143.747 1.00 13.62 ? 314 SER N N 1 ATOM 1846 C CA . SER A 1 235 ? 43.764 19.343 142.478 1.00 12.20 ? 314 SER N CA 1 ATOM 1847 C C . SER A 1 235 ? 43.139 20.592 141.899 1.00 9.67 ? 314 SER N C 1 ATOM 1848 O O . SER A 1 235 ? 41.912 20.652 141.798 1.00 10.04 ? 314 SER N O 1 ATOM 1849 C CB . SER A 1 235 ? 43.614 18.228 141.477 1.00 11.05 ? 314 SER N CB 1 ATOM 1850 O OG . SER A 1 235 ? 42.274 17.783 141.292 1.00 12.75 ? 314 SER N OG 1 ATOM 1851 N N . GLN A 1 236 ? 43.873 21.634 141.527 1.00 7.69 ? 315 GLN N N 1 ATOM 1852 C CA . GLN A 1 236 ? 43.249 22.786 140.885 1.00 6.88 ? 315 GLN N CA 1 ATOM 1853 C C . GLN A 1 236 ? 43.985 23.134 139.613 1.00 3.71 ? 315 GLN N C 1 ATOM 1854 O O . GLN A 1 236 ? 44.746 22.269 139.159 1.00 4.34 ? 315 GLN N O 1 ATOM 1855 C CB . GLN A 1 236 ? 43.243 23.993 141.807 1.00 7.38 ? 315 GLN N CB 1 ATOM 1856 C CG . GLN A 1 236 ? 44.601 24.258 142.285 1.00 10.73 ? 315 GLN N CG 1 ATOM 1857 C CD . GLN A 1 236 ? 44.673 25.668 142.784 1.00 12.68 ? 315 GLN N CD 1 ATOM 1858 O OE1 . GLN A 1 236 ? 44.382 26.659 142.097 1.00 13.73 ? 315 GLN N OE1 1 ATOM 1859 N NE2 . GLN A 1 236 ? 45.095 25.687 144.049 1.00 11.95 ? 315 GLN N NE2 1 ATOM 1860 N N . TYR A 1 237 ? 43.812 24.257 138.933 1.00 2.00 ? 316 TYR N N 1 ATOM 1861 C CA . TYR A 1 237 ? 44.696 24.463 137.814 1.00 4.02 ? 316 TYR N CA 1 ATOM 1862 C C . TYR A 1 237 ? 45.563 25.634 138.218 1.00 5.09 ? 316 TYR N C 1 ATOM 1863 O O . TYR A 1 237 ? 45.502 26.131 139.345 1.00 8.18 ? 316 TYR N O 1 ATOM 1864 C CB . TYR A 1 237 ? 43.916 24.749 136.518 1.00 2.71 ? 316 TYR N CB 1 ATOM 1865 C CG . TYR A 1 237 ? 43.299 23.515 135.848 1.00 2.32 ? 316 TYR N CG 1 ATOM 1866 C CD1 . TYR A 1 237 ? 42.327 22.772 136.483 1.00 3.22 ? 316 TYR N CD1 1 ATOM 1867 C CD2 . TYR A 1 237 ? 43.715 23.112 134.593 1.00 5.07 ? 316 TYR N CD2 1 ATOM 1868 C CE1 . TYR A 1 237 ? 41.788 21.655 135.871 1.00 3.47 ? 316 TYR N CE1 1 ATOM 1869 C CE2 . TYR A 1 237 ? 43.190 21.997 133.983 1.00 6.31 ? 316 TYR N CE2 1 ATOM 1870 C CZ . TYR A 1 237 ? 42.243 21.286 134.637 1.00 3.89 ? 316 TYR N CZ 1 ATOM 1871 O OH . TYR A 1 237 ? 41.806 20.145 134.062 1.00 4.82 ? 316 TYR N OH 1 ATOM 1872 N N . ILE A 1 238 ? 46.519 25.888 137.336 1.00 6.63 ? 317 ILE N N 1 ATOM 1873 C CA . ILE A 1 238 ? 47.382 27.021 137.442 1.00 7.24 ? 317 ILE N CA 1 ATOM 1874 C C . ILE A 1 238 ? 46.479 28.076 136.881 1.00 10.82 ? 317 ILE N C 1 ATOM 1875 O O . ILE A 1 238 ? 46.123 27.969 135.694 1.00 12.84 ? 317 ILE N O 1 ATOM 1876 C CB . ILE A 1 238 ? 48.623 26.835 136.556 1.00 7.42 ? 317 ILE N CB 1 ATOM 1877 C CG1 . ILE A 1 238 ? 49.630 26.010 137.343 1.00 7.15 ? 317 ILE N CG1 1 ATOM 1878 C CG2 . ILE A 1 238 ? 49.263 28.153 136.170 1.00 7.50 ? 317 ILE N CG2 1 ATOM 1879 C CD1 . ILE A 1 238 ? 50.915 25.659 136.583 1.00 6.85 ? 317 ILE N CD1 1 ATOM 1880 N N . CYS A 1 239 ? 46.084 29.050 137.727 1.00 12.21 ? 318 CYS N N 1 ATOM 1881 C CA . CYS A 1 239 ? 45.321 30.238 137.310 1.00 11.05 ? 318 CYS N CA 1 ATOM 1882 C C . CYS A 1 239 ? 45.971 31.103 136.208 1.00 9.87 ? 318 CYS N C 1 ATOM 1883 O O . CYS A 1 239 ? 45.276 31.533 135.288 1.00 10.21 ? 318 CYS N O 1 ATOM 1884 C CB . CYS A 1 239 ? 45.067 31.205 138.460 1.00 11.40 ? 318 CYS N CB 1 ATOM 1885 S SG . CYS A 1 239 ? 44.026 30.675 139.833 1.00 12.30 ? 318 CYS N SG 1 ATOM 1886 N N . SER A 1 240 ? 47.264 31.412 136.315 1.00 8.72 ? 319 SER N N 1 ATOM 1887 C CA . SER A 1 240 ? 47.941 32.295 135.419 1.00 9.67 ? 319 SER N CA 1 ATOM 1888 C C . SER A 1 240 ? 47.531 32.203 133.989 1.00 8.99 ? 319 SER N C 1 ATOM 1889 O O . SER A 1 240 ? 47.409 31.111 133.456 1.00 10.20 ? 319 SER N O 1 ATOM 1890 C CB . SER A 1 240 ? 49.421 32.098 135.409 1.00 9.95 ? 319 SER N CB 1 ATOM 1891 O OG . SER A 1 240 ? 49.997 33.160 134.635 1.00 11.61 ? 319 SER N OG 1 ATOM 1892 N N . PRO A 1 241 ? 47.304 33.319 133.319 1.00 9.44 ? 320 PRO N N 1 ATOM 1893 C CA . PRO A 1 241 ? 47.243 33.400 131.878 1.00 10.95 ? 320 PRO N CA 1 ATOM 1894 C C . PRO A 1 241 ? 48.492 32.862 131.174 1.00 10.51 ? 320 PRO N C 1 ATOM 1895 O O . PRO A 1 241 ? 48.362 32.407 130.027 1.00 15.13 ? 320 PRO N O 1 ATOM 1896 C CB . PRO A 1 241 ? 46.976 34.879 131.635 1.00 9.40 ? 320 PRO N CB 1 ATOM 1897 C CG . PRO A 1 241 ? 47.692 35.538 132.783 1.00 9.55 ? 320 PRO N CG 1 ATOM 1898 C CD . PRO A 1 241 ? 47.176 34.648 133.898 1.00 8.74 ? 320 PRO N CD 1 ATOM 1899 N N . VAL A 1 242 ? 49.685 32.874 131.785 1.00 7.99 ? 321 VAL N N 1 ATOM 1900 C CA . VAL A 1 242 ? 50.887 32.373 131.157 1.00 6.23 ? 321 VAL N CA 1 ATOM 1901 C C . VAL A 1 242 ? 50.676 30.870 130.998 1.00 6.68 ? 321 VAL N C 1 ATOM 1902 O O . VAL A 1 242 ? 50.897 30.112 131.943 1.00 9.10 ? 321 VAL N O 1 ATOM 1903 C CB . VAL A 1 242 ? 52.097 32.723 132.050 1.00 6.59 ? 321 VAL N CB 1 ATOM 1904 C CG1 . VAL A 1 242 ? 53.401 32.296 131.322 1.00 5.73 ? 321 VAL N CG1 1 ATOM 1905 C CG2 . VAL A 1 242 ? 52.056 34.214 132.420 1.00 6.89 ? 321 VAL N CG2 1 ATOM 1906 N N . LEU A 1 243 ? 50.084 30.472 129.855 1.00 6.63 ? 322 LEU N N 1 ATOM 1907 C CA . LEU A 1 243 ? 49.797 29.067 129.572 1.00 7.83 ? 322 LEU N CA 1 ATOM 1908 C C . LEU A 1 243 ? 51.114 28.336 129.456 1.00 9.80 ? 322 LEU N C 1 ATOM 1909 O O . LEU A 1 243 ? 52.061 28.894 128.883 1.00 12.46 ? 322 LEU N O 1 ATOM 1910 C CB . LEU A 1 243 ? 49.036 28.874 128.275 1.00 4.99 ? 322 LEU N CB 1 ATOM 1911 C CG . LEU A 1 243 ? 47.622 29.411 128.146 1.00 5.85 ? 322 LEU N CG 1 ATOM 1912 C CD1 . LEU A 1 243 ? 47.068 28.926 126.829 1.00 2.00 ? 322 LEU N CD1 1 ATOM 1913 C CD2 . LEU A 1 243 ? 46.741 28.962 129.295 1.00 2.12 ? 322 LEU N CD2 1 ATOM 1914 N N . THR A 1 244 ? 51.276 27.131 129.996 1.00 7.80 ? 323 THR N N 1 ATOM 1915 C CA . THR A 1 244 ? 52.582 26.493 129.855 1.00 6.47 ? 323 THR N CA 1 ATOM 1916 C C . THR A 1 244 ? 52.620 25.160 129.139 1.00 6.72 ? 323 THR N C 1 ATOM 1917 O O . THR A 1 244 ? 53.709 24.693 128.779 1.00 8.78 ? 323 THR N O 1 ATOM 1918 C CB . THR A 1 244 ? 53.201 26.370 131.251 1.00 5.73 ? 323 THR N CB 1 ATOM 1919 O OG1 . THR A 1 244 ? 52.124 26.127 132.142 1.00 4.91 ? 323 THR N OG1 1 ATOM 1920 C CG2 . THR A 1 244 ? 53.955 27.611 131.709 1.00 4.68 ? 323 THR N CG2 1 ATOM 1921 N N . ASP A 1 245 ? 51.477 24.529 128.887 1.00 4.39 ? 324 ASP N N 1 ATOM 1922 C CA . ASP A 1 245 ? 51.474 23.283 128.155 1.00 4.01 ? 324 ASP N CA 1 ATOM 1923 C C . ASP A 1 245 ? 51.825 23.558 126.688 1.00 3.92 ? 324 ASP N C 1 ATOM 1924 O O . ASP A 1 245 ? 51.947 24.696 126.263 1.00 2.87 ? 324 ASP N O 1 ATOM 1925 C CB . ASP A 1 245 ? 50.107 22.681 128.290 1.00 2.00 ? 324 ASP N CB 1 ATOM 1926 C CG . ASP A 1 245 ? 49.937 21.205 127.918 1.00 2.00 ? 324 ASP N CG 1 ATOM 1927 O OD1 . ASP A 1 245 ? 50.860 20.567 127.390 1.00 2.23 ? 324 ASP N OD1 1 ATOM 1928 O OD2 . ASP A 1 245 ? 48.847 20.685 128.183 1.00 5.08 ? 324 ASP N OD2 1 ATOM 1929 N N . ASN A 1 246 ? 51.838 22.577 125.794 1.00 5.00 ? 325 ASN N N 1 ATOM 1930 C CA . ASN A 1 246 ? 52.337 22.714 124.436 1.00 6.11 ? 325 ASN N CA 1 ATOM 1931 C C . ASN A 1 246 ? 51.806 21.545 123.622 1.00 5.47 ? 325 ASN N C 1 ATOM 1932 O O . ASN A 1 246 ? 51.844 20.445 124.170 1.00 5.64 ? 325 ASN N O 1 ATOM 1933 C CB . ASN A 1 246 ? 53.812 22.648 124.487 1.00 9.51 ? 325 ASN N CB 1 ATOM 1934 C CG . ASN A 1 246 ? 54.341 22.797 123.103 1.00 10.40 ? 325 ASN N CG 1 ATOM 1935 O OD1 . ASN A 1 246 ? 54.599 21.843 122.379 1.00 12.50 ? 325 ASN N OD1 1 ATOM 1936 N ND2 . ASN A 1 246 ? 54.449 24.072 122.766 1.00 10.46 ? 325 ASN N ND2 1 ATOM 1937 N N . PRO A 1 247 ? 51.208 21.677 122.436 1.00 6.89 ? 326 PRO N N 1 ATOM 1938 C CA . PRO A 1 247 ? 50.691 22.926 121.851 1.00 7.43 ? 326 PRO N CA 1 ATOM 1939 C C . PRO A 1 247 ? 49.703 23.708 122.690 1.00 8.43 ? 326 PRO N C 1 ATOM 1940 O O . PRO A 1 247 ? 49.011 23.122 123.538 1.00 4.53 ? 326 PRO N O 1 ATOM 1941 C CB . PRO A 1 247 ? 50.092 22.527 120.532 1.00 3.15 ? 326 PRO N CB 1 ATOM 1942 C CG . PRO A 1 247 ? 49.767 21.085 120.769 1.00 4.62 ? 326 PRO N CG 1 ATOM 1943 C CD . PRO A 1 247 ? 50.917 20.550 121.579 1.00 5.12 ? 326 PRO N CD 1 ATOM 1944 N N . ARG A 1 248 ? 49.667 25.022 122.499 1.00 10.89 ? 327 ARG N N 1 ATOM 1945 C CA . ARG A 1 248 ? 48.743 25.786 123.281 1.00 13.32 ? 327 ARG N CA 1 ATOM 1946 C C . ARG A 1 248 ? 48.180 26.853 122.400 1.00 16.96 ? 327 ARG N C 1 ATOM 1947 O O . ARG A 1 248 ? 48.850 27.238 121.442 1.00 20.56 ? 327 ARG N O 1 ATOM 1948 C CB . ARG A 1 248 ? 49.431 26.397 124.506 1.00 12.62 ? 327 ARG N CB 1 ATOM 1949 C CG . ARG A 1 248 ? 50.689 27.193 124.270 1.00 11.44 ? 327 ARG N CG 1 ATOM 1950 C CD . ARG A 1 248 ? 51.398 27.734 125.533 1.00 9.85 ? 327 ARG N CD 1 ATOM 1951 N NE . ARG A 1 248 ? 52.592 28.536 125.158 1.00 9.75 ? 327 ARG N NE 1 ATOM 1952 C CZ . ARG A 1 248 ? 53.772 28.006 124.788 1.00 12.35 ? 327 ARG N CZ 1 ATOM 1953 N NH1 . ARG A 1 248 ? 53.944 26.698 124.864 1.00 12.89 ? 327 ARG N NH1 1 ATOM 1954 N NH2 . ARG A 1 248 ? 54.807 28.751 124.384 1.00 12.64 ? 327 ARG N NH2 1 ATOM 1955 N N . PRO A 1 249 ? 46.908 27.242 122.614 1.00 19.32 ? 328 PRO N N 1 ATOM 1956 C CA . PRO A 1 249 ? 46.359 28.564 122.331 1.00 19.93 ? 328 PRO N CA 1 ATOM 1957 C C . PRO A 1 249 ? 47.223 29.686 122.846 1.00 21.61 ? 328 PRO N C 1 ATOM 1958 O O . PRO A 1 249 ? 47.961 29.508 123.820 1.00 23.27 ? 328 PRO N O 1 ATOM 1959 C CB . PRO A 1 249 ? 45.023 28.549 122.978 1.00 17.78 ? 328 PRO N CB 1 ATOM 1960 C CG . PRO A 1 249 ? 45.072 27.421 123.965 1.00 18.73 ? 328 PRO N CG 1 ATOM 1961 C CD . PRO A 1 249 ? 45.871 26.402 123.205 1.00 19.53 ? 328 PRO N CD 1 ATOM 1962 N N . ASP A 1 250 ? 47.124 30.872 122.257 1.00 24.05 ? 329 ASP N N 1 ATOM 1963 C CA . ASP A 1 250 ? 47.972 31.988 122.666 1.00 24.14 ? 329 ASP N CA 1 ATOM 1964 C C . ASP A 1 250 ? 47.522 32.485 124.029 1.00 21.29 ? 329 ASP N C 1 ATOM 1965 O O . ASP A 1 250 ? 46.330 32.437 124.321 1.00 21.57 ? 329 ASP N O 1 ATOM 1966 C CB . ASP A 1 250 ? 47.892 33.075 121.563 1.00 25.46 ? 329 ASP N CB 1 ATOM 1967 C CG . ASP A 1 250 ? 47.798 34.560 121.989 1.00 26.38 ? 329 ASP N CG 1 ATOM 1968 O OD1 . ASP A 1 250 ? 48.829 35.254 122.158 1.00 21.87 ? 329 ASP N OD1 1 ATOM 1969 O OD2 . ASP A 1 250 ? 46.645 35.016 122.126 1.00 32.13 ? 329 ASP N OD2 1 ATOM 1970 N N . ASP A 1 251 ? 48.411 32.965 124.884 1.00 19.59 ? 330 ASP N N 1 ATOM 1971 C CA . ASP A 1 251 ? 48.005 33.349 126.240 1.00 15.35 ? 330 ASP N CA 1 ATOM 1972 C C . ASP A 1 251 ? 47.096 34.566 126.315 1.00 13.49 ? 330 ASP N C 1 ATOM 1973 O O . ASP A 1 251 ? 47.398 35.622 125.718 1.00 11.96 ? 330 ASP N O 1 ATOM 1974 C CB . ASP A 1 251 ? 49.130 33.708 127.191 1.00 13.63 ? 330 ASP N CB 1 ATOM 1975 C CG . ASP A 1 251 ? 50.483 33.156 126.909 1.00 13.85 ? 330 ASP N CG 1 ATOM 1976 O OD1 . ASP A 1 251 ? 50.625 32.014 126.470 1.00 16.32 ? 330 ASP N OD1 1 ATOM 1977 O OD2 . ASP A 1 251 ? 51.403 33.921 127.127 1.00 12.52 ? 330 ASP N OD2 1 ATOM 1978 N N . PRO A 1 252 ? 46.003 34.383 127.083 1.00 12.59 ? 331 PRO N N 1 ATOM 1979 C CA . PRO A 1 252 ? 44.949 35.357 127.368 1.00 15.09 ? 331 PRO N CA 1 ATOM 1980 C C . PRO A 1 252 ? 45.317 36.526 128.285 1.00 15.35 ? 331 PRO N C 1 ATOM 1981 O O . PRO A 1 252 ? 46.478 36.742 128.603 1.00 17.86 ? 331 PRO N O 1 ATOM 1982 C CB . PRO A 1 252 ? 43.862 34.480 127.904 1.00 11.71 ? 331 PRO N CB 1 ATOM 1983 C CG . PRO A 1 252 ? 44.656 33.505 128.719 1.00 10.38 ? 331 PRO N CG 1 ATOM 1984 C CD . PRO A 1 252 ? 45.634 33.106 127.676 1.00 13.28 ? 331 PRO N CD 1 ATOM 1985 N N . THR A 1 253 ? 44.359 37.314 128.765 1.00 18.54 ? 332 THR N N 1 ATOM 1986 C CA . THR A 1 253 ? 44.660 38.432 129.676 1.00 21.37 ? 332 THR N CA 1 ATOM 1987 C C . THR A 1 253 ? 44.386 38.121 131.156 1.00 22.27 ? 332 THR N C 1 ATOM 1988 O O . THR A 1 253 ? 45.032 38.660 132.072 1.00 22.67 ? 332 THR N O 1 ATOM 1989 C CB . THR A 1 253 ? 43.832 39.656 129.231 1.00 19.39 ? 332 THR N CB 1 ATOM 1990 O OG1 . THR A 1 253 ? 42.573 39.122 128.837 1.00 19.00 ? 332 THR N OG1 1 ATOM 1991 C CG2 . THR A 1 253 ? 44.444 40.436 128.093 1.00 20.55 ? 332 THR N CG2 1 ATOM 1992 N N . VAL A 1 254 ? 43.431 37.174 131.272 1.00 20.11 ? 333 VAL N N 1 ATOM 1993 C CA . VAL A 1 254 ? 42.800 36.653 132.467 1.00 20.57 ? 333 VAL N CA 1 ATOM 1994 C C . VAL A 1 254 ? 42.759 35.162 132.180 1.00 19.59 ? 333 VAL N C 1 ATOM 1995 O O . VAL A 1 254 ? 42.552 34.876 131.008 1.00 22.01 ? 333 VAL N O 1 ATOM 1996 C CB . VAL A 1 254 ? 41.380 37.201 132.577 1.00 23.24 ? 333 VAL N CB 1 ATOM 1997 C CG1 . VAL A 1 254 ? 40.810 36.731 133.885 1.00 25.65 ? 333 VAL N CG1 1 ATOM 1998 C CG2 . VAL A 1 254 ? 41.340 38.717 132.581 1.00 23.59 ? 333 VAL N CG2 1 ATOM 1999 N N . GLY A 1 255 ? 42.864 34.195 133.099 1.00 17.07 ? 335 GLY N N 1 ATOM 2000 C CA . GLY A 1 255 ? 42.932 32.783 132.731 1.00 16.68 ? 335 GLY N CA 1 ATOM 2001 C C . GLY A 1 255 ? 41.866 31.916 133.357 1.00 15.60 ? 335 GLY N C 1 ATOM 2002 O O . GLY A 1 255 ? 40.726 32.322 133.335 1.00 15.70 ? 335 GLY N O 1 ATOM 2003 N N . LYS A 1 256 ? 42.089 30.725 133.925 1.00 16.57 ? 336 LYS N N 1 ATOM 2004 C CA . LYS A 1 256 ? 41.029 29.870 134.495 1.00 16.05 ? 336 LYS N CA 1 ATOM 2005 C C . LYS A 1 256 ? 41.600 29.028 135.604 1.00 17.32 ? 336 LYS N C 1 ATOM 2006 O O . LYS A 1 256 ? 42.424 28.148 135.347 1.00 19.03 ? 336 LYS N O 1 ATOM 2007 C CB . LYS A 1 256 ? 40.410 28.838 133.501 1.00 16.85 ? 336 LYS N CB 1 ATOM 2008 C CG . LYS A 1 256 ? 39.387 29.391 132.521 1.00 18.10 ? 336 LYS N CG 1 ATOM 2009 C CD . LYS A 1 256 ? 38.922 28.541 131.299 1.00 19.20 ? 336 LYS N CD 1 ATOM 2010 C CE . LYS A 1 256 ? 37.679 29.229 130.665 1.00 20.18 ? 336 LYS N CE 1 ATOM 2011 N NZ . LYS A 1 256 ? 37.979 30.587 130.226 1.00 22.05 ? 336 LYS N NZ 1 ATOM 2012 N N . CYS A 1 257 ? 41.155 29.232 136.836 1.00 17.29 ? 337 CYS N N 1 ATOM 2013 C CA . CYS A 1 257 ? 41.709 28.459 137.933 1.00 15.76 ? 337 CYS N CA 1 ATOM 2014 C C . CYS A 1 257 ? 41.073 27.118 138.105 1.00 17.60 ? 337 CYS N C 1 ATOM 2015 O O . CYS A 1 257 ? 41.740 26.119 138.356 1.00 16.98 ? 337 CYS N O 1 ATOM 2016 C CB . CYS A 1 257 ? 41.542 29.131 139.246 1.00 12.17 ? 337 CYS N CB 1 ATOM 2017 S SG . CYS A 1 257 ? 42.158 30.806 139.135 1.00 15.26 ? 337 CYS N SG 1 ATOM 2018 N N . ASN A 1 258 ? 39.752 27.059 138.062 1.00 19.36 ? 338 ASN N N 1 ATOM 2019 C CA . ASN A 1 258 ? 39.144 25.797 138.401 1.00 23.18 ? 338 ASN N CA 1 ATOM 2020 C C . ASN A 1 258 ? 38.647 24.982 137.270 1.00 24.66 ? 338 ASN N C 1 ATOM 2021 O O . ASN A 1 258 ? 37.803 24.123 137.490 1.00 25.55 ? 338 ASN N O 1 ATOM 2022 C CB . ASN A 1 258 ? 38.014 26.046 139.403 1.00 24.43 ? 338 ASN N CB 1 ATOM 2023 C CG . ASN A 1 258 ? 38.581 26.308 140.785 1.00 25.48 ? 338 ASN N CG 1 ATOM 2024 O OD1 . ASN A 1 258 ? 39.551 25.658 141.165 1.00 24.20 ? 338 ASN N OD1 1 ATOM 2025 N ND2 . ASN A 1 258 ? 38.041 27.228 141.590 1.00 26.87 ? 338 ASN N ND2 1 ATOM 2026 N N . ASP A 1 259 ? 39.187 25.211 136.078 1.00 24.46 ? 339 ASP N N 1 ATOM 2027 C CA . ASP A 1 259 ? 38.775 24.500 134.882 1.00 24.76 ? 339 ASP N CA 1 ATOM 2028 C C . ASP A 1 259 ? 39.918 24.484 133.865 1.00 22.10 ? 339 ASP N C 1 ATOM 2029 O O . ASP A 1 259 ? 40.812 25.350 133.971 1.00 24.71 ? 339 ASP N O 1 ATOM 2030 C CB . ASP A 1 259 ? 37.551 25.190 134.263 1.00 29.25 ? 339 ASP N CB 1 ATOM 2031 C CG . ASP A 1 259 ? 36.188 24.752 134.788 1.00 31.31 ? 339 ASP N CG 1 ATOM 2032 O OD1 . ASP A 1 259 ? 35.940 23.552 134.947 1.00 33.22 ? 339 ASP N OD1 1 ATOM 2033 O OD2 . ASP A 1 259 ? 35.372 25.633 135.037 1.00 32.87 ? 339 ASP N OD2 1 ATOM 2034 N N . PRO A 1 260 ? 39.973 23.547 132.893 1.00 18.34 ? 340 PRO N N 1 ATOM 2035 C CA . PRO A 1 260 ? 40.875 23.621 131.741 1.00 18.11 ? 340 PRO N CA 1 ATOM 2036 C C . PRO A 1 260 ? 40.724 24.830 130.847 1.00 20.18 ? 340 PRO N C 1 ATOM 2037 O O . PRO A 1 260 ? 39.598 25.248 130.541 1.00 21.54 ? 340 PRO N O 1 ATOM 2038 C CB . PRO A 1 260 ? 40.639 22.355 130.988 1.00 15.72 ? 340 PRO N CB 1 ATOM 2039 C CG . PRO A 1 260 ? 39.287 21.905 131.449 1.00 16.58 ? 340 PRO N CG 1 ATOM 2040 C CD . PRO A 1 260 ? 39.251 22.288 132.917 1.00 17.54 ? 340 PRO N CD 1 ATOM 2041 N N . TYR A 1 261 ? 41.814 25.417 130.358 1.00 21.34 ? 341 TYR N N 1 ATOM 2042 C CA . TYR A 1 261 ? 41.674 26.584 129.500 1.00 23.21 ? 341 TYR N CA 1 ATOM 2043 C C . TYR A 1 261 ? 41.544 26.131 128.048 1.00 24.01 ? 341 TYR N C 1 ATOM 2044 O O . TYR A 1 261 ? 42.415 25.409 127.539 1.00 25.24 ? 341 TYR N O 1 ATOM 2045 C CB . TYR A 1 261 ? 42.883 27.521 129.661 1.00 24.97 ? 341 TYR N CB 1 ATOM 2046 C CG . TYR A 1 261 ? 42.534 28.825 128.973 1.00 24.12 ? 341 TYR N CG 1 ATOM 2047 C CD1 . TYR A 1 261 ? 41.869 29.824 129.652 1.00 24.41 ? 341 TYR N CD1 1 ATOM 2048 C CD2 . TYR A 1 261 ? 42.812 28.951 127.635 1.00 24.32 ? 341 TYR N CD2 1 ATOM 2049 C CE1 . TYR A 1 261 ? 41.476 30.947 128.969 1.00 24.72 ? 341 TYR N CE1 1 ATOM 2050 C CE2 . TYR A 1 261 ? 42.417 30.068 126.954 1.00 25.32 ? 341 TYR N CE2 1 ATOM 2051 C CZ . TYR A 1 261 ? 41.747 31.052 127.622 1.00 25.83 ? 341 TYR N CZ 1 ATOM 2052 O OH . TYR A 1 261 ? 41.310 32.126 126.881 1.00 25.79 ? 341 TYR N OH 1 ATOM 2053 N N . PRO A 1 262 ? 40.499 26.547 127.333 1.00 22.39 ? 342 PRO N N 1 ATOM 2054 C CA . PRO A 1 262 ? 40.159 26.000 126.035 1.00 22.76 ? 342 PRO N CA 1 ATOM 2055 C C . PRO A 1 262 ? 41.134 26.347 124.927 1.00 24.98 ? 342 PRO N C 1 ATOM 2056 O O . PRO A 1 262 ? 41.892 27.321 125.007 1.00 24.23 ? 342 PRO N O 1 ATOM 2057 C CB . PRO A 1 262 ? 38.789 26.513 125.776 1.00 22.42 ? 342 PRO N CB 1 ATOM 2058 C CG . PRO A 1 262 ? 38.800 27.830 126.499 1.00 23.02 ? 342 PRO N CG 1 ATOM 2059 C CD . PRO A 1 262 ? 39.455 27.443 127.798 1.00 23.66 ? 342 PRO N CD 1 ATOM 2060 N N . GLY A 1 263 ? 41.107 25.529 123.873 1.00 24.91 ? 343 GLY N N 1 ATOM 2061 C CA . GLY A 1 263 ? 41.892 25.795 122.694 1.00 26.89 ? 343 GLY N CA 1 ATOM 2062 C C . GLY A 1 263 ? 42.570 24.566 122.134 1.00 28.93 ? 343 GLY N C 1 ATOM 2063 O O . GLY A 1 263 ? 42.400 24.329 120.941 1.00 30.27 ? 343 GLY N O 1 ATOM 2064 N N . ASN A 1 264 ? 43.360 23.759 122.860 1.00 31.16 ? 344 ASN N N 1 ATOM 2065 C CA . ASN A 1 264 ? 43.996 22.603 122.220 1.00 30.54 ? 344 ASN N CA 1 ATOM 2066 C C . ASN A 1 264 ? 43.789 21.321 122.989 1.00 32.00 ? 344 ASN N C 1 ATOM 2067 O O . ASN A 1 264 ? 44.370 20.945 124.027 1.00 33.65 ? 344 ASN N O 1 ATOM 2068 C CB . ASN A 1 264 ? 45.499 22.820 122.037 1.00 29.39 ? 344 ASN N CB 1 ATOM 2069 C CG . ASN A 1 264 ? 46.185 21.747 121.199 1.00 29.39 ? 344 ASN N CG 1 ATOM 2070 O OD1 . ASN A 1 264 ? 46.436 20.626 121.645 1.00 28.42 ? 344 ASN N OD1 1 ATOM 2071 N ND2 . ASN A 1 264 ? 46.567 22.029 119.962 1.00 29.22 ? 344 ASN N ND2 1 ATOM 2072 N N . ASN A 1 265 ? 42.842 20.670 122.359 1.00 34.42 ? 345 ASN N N 1 ATOM 2073 C CA . ASN A 1 265 ? 42.406 19.380 122.826 1.00 36.31 ? 345 ASN N CA 1 ATOM 2074 C C . ASN A 1 265 ? 43.258 18.242 122.242 1.00 32.23 ? 345 ASN N C 1 ATOM 2075 O O . ASN A 1 265 ? 43.816 18.337 121.150 1.00 31.14 ? 345 ASN N O 1 ATOM 2076 C CB . ASN A 1 265 ? 40.912 19.214 122.474 1.00 41.59 ? 345 ASN N CB 1 ATOM 2077 C CG . ASN A 1 265 ? 40.478 19.683 121.084 1.00 46.97 ? 345 ASN N CG 1 ATOM 2078 O OD1 . ASN A 1 265 ? 39.303 19.997 120.881 1.00 50.19 ? 345 ASN N OD1 1 ATOM 2079 N ND2 . ASN A 1 265 ? 41.335 19.802 120.058 1.00 48.48 ? 345 ASN N ND2 1 ATOM 2080 N N . ASN A 1 266 ? 43.330 17.188 123.064 1.00 30.18 ? 346 ASN N N 1 ATOM 2081 C CA . ASN A 1 266 ? 44.018 15.901 122.902 1.00 27.96 ? 346 ASN N CA 1 ATOM 2082 C C . ASN A 1 266 ? 45.499 15.966 122.492 1.00 25.12 ? 346 ASN N C 1 ATOM 2083 O O . ASN A 1 266 ? 46.013 15.418 121.519 1.00 27.72 ? 346 ASN N O 1 ATOM 2084 C CB . ASN A 1 266 ? 43.159 15.048 121.937 1.00 28.31 ? 346 ASN N CB 1 ATOM 2085 C CG . ASN A 1 266 ? 41.701 14.845 122.387 1.00 26.79 ? 346 ASN N CG 1 ATOM 2086 O OD1 . ASN A 1 266 ? 40.807 14.646 121.583 1.00 28.68 ? 346 ASN N OD1 1 ATOM 2087 N ND2 . ASN A 1 266 ? 41.257 14.875 123.632 1.00 25.36 ? 346 ASN N ND2 1 ATOM 2088 N N . ASN A 1 267 ? 46.192 16.558 123.484 1.00 23.29 ? 347 ASN N N 1 ATOM 2089 C CA . ASN A 1 267 ? 47.602 16.941 123.475 1.00 19.29 ? 347 ASN N CA 1 ATOM 2090 C C . ASN A 1 267 ? 48.036 17.756 124.706 1.00 15.76 ? 347 ASN N C 1 ATOM 2091 O O . ASN A 1 267 ? 47.318 18.582 125.449 1.00 16.30 ? 347 ASN N O 1 ATOM 2092 C CB . ASN A 1 267 ? 47.928 17.798 122.273 1.00 18.87 ? 347 ASN N CB 1 ATOM 2093 C CG . ASN A 1 267 ? 48.935 17.226 121.323 1.00 18.90 ? 347 ASN N CG 1 ATOM 2094 O OD1 . ASN A 1 267 ? 49.847 16.545 121.747 1.00 22.45 ? 347 ASN N OD1 1 ATOM 2095 N ND2 . ASN A 1 267 ? 48.805 17.465 120.033 1.00 19.11 ? 347 ASN N ND2 1 ATOM 2096 N N . GLY A 1 268 ? 49.358 17.526 124.759 1.00 14.58 ? 348 GLY N N 1 ATOM 2097 C CA . GLY A 1 268 ? 50.266 18.077 125.760 1.00 11.67 ? 348 GLY N CA 1 ATOM 2098 C C . GLY A 1 268 ? 51.763 17.744 125.595 1.00 10.51 ? 348 GLY N C 1 ATOM 2099 O O . GLY A 1 268 ? 52.245 17.480 124.500 1.00 13.68 ? 348 GLY N O 1 ATOM 2100 N N . VAL A 1 269 ? 52.540 17.729 126.683 1.00 8.91 ? 349 VAL N N 1 ATOM 2101 C CA . VAL A 1 269 ? 53.986 17.452 126.735 1.00 5.29 ? 349 VAL N CA 1 ATOM 2102 C C . VAL A 1 269 ? 54.291 17.448 128.216 1.00 3.93 ? 349 VAL N C 1 ATOM 2103 O O . VAL A 1 269 ? 53.780 18.342 128.843 1.00 6.19 ? 349 VAL N O 1 ATOM 2104 C CB . VAL A 1 269 ? 54.808 18.542 126.017 1.00 2.23 ? 349 VAL N CB 1 ATOM 2105 C CG1 . VAL A 1 269 ? 54.668 19.888 126.609 1.00 2.00 ? 349 VAL N CG1 1 ATOM 2106 C CG2 . VAL A 1 269 ? 56.250 18.112 126.090 1.00 4.36 ? 349 VAL N CG2 1 ATOM 2107 N N . LYS A 1 270 ? 54.969 16.544 128.906 1.00 3.25 ? 350 LYS N N 1 ATOM 2108 C CA . LYS A 1 270 ? 55.124 16.568 130.366 1.00 2.00 ? 350 LYS N CA 1 ATOM 2109 C C . LYS A 1 270 ? 55.755 17.860 130.784 1.00 2.91 ? 350 LYS N C 1 ATOM 2110 O O . LYS A 1 270 ? 56.622 18.282 130.010 1.00 4.43 ? 350 LYS N O 1 ATOM 2111 C CB . LYS A 1 270 ? 55.991 15.412 130.730 1.00 4.64 ? 350 LYS N CB 1 ATOM 2112 C CG . LYS A 1 270 ? 56.506 15.344 132.135 1.00 4.29 ? 350 LYS N CG 1 ATOM 2113 C CD . LYS A 1 270 ? 57.133 14.030 132.440 1.00 4.74 ? 350 LYS N CD 1 ATOM 2114 C CE . LYS A 1 270 ? 57.861 14.236 133.747 1.00 8.18 ? 350 LYS N CE 1 ATOM 2115 N NZ . LYS A 1 270 ? 57.016 14.538 134.878 1.00 7.82 ? 350 LYS N NZ 1 ATOM 2116 N N . GLY A 1 271 ? 55.453 18.520 131.903 1.00 4.86 ? 351 GLY N N 1 ATOM 2117 C CA . GLY A 1 271 ? 56.039 19.841 132.130 1.00 3.03 ? 351 GLY N CA 1 ATOM 2118 C C . GLY A 1 271 ? 56.152 20.077 133.615 1.00 2.97 ? 351 GLY N C 1 ATOM 2119 O O . GLY A 1 271 ? 55.700 19.216 134.356 1.00 6.09 ? 351 GLY N O 1 ATOM 2120 N N . PHE A 1 272 ? 56.666 21.162 134.156 1.00 2.94 ? 352 PHE N N 1 ATOM 2121 C CA . PHE A 1 272 ? 56.813 21.317 135.575 1.00 2.70 ? 352 PHE N CA 1 ATOM 2122 C C . PHE A 1 272 ? 56.557 22.795 135.966 1.00 3.98 ? 352 PHE N C 1 ATOM 2123 O O . PHE A 1 272 ? 56.337 23.632 135.074 1.00 2.00 ? 352 PHE N O 1 ATOM 2124 C CB . PHE A 1 272 ? 58.232 20.847 135.926 1.00 2.22 ? 352 PHE N CB 1 ATOM 2125 C CG . PHE A 1 272 ? 59.310 21.880 135.632 1.00 2.61 ? 352 PHE N CG 1 ATOM 2126 C CD1 . PHE A 1 272 ? 59.618 22.912 136.537 1.00 3.81 ? 352 PHE N CD1 1 ATOM 2127 C CD2 . PHE A 1 272 ? 59.970 21.799 134.433 1.00 2.57 ? 352 PHE N CD2 1 ATOM 2128 C CE1 . PHE A 1 272 ? 60.577 23.852 136.207 1.00 4.13 ? 352 PHE N CE1 1 ATOM 2129 C CE2 . PHE A 1 272 ? 60.931 22.765 134.138 1.00 3.64 ? 352 PHE N CE2 1 ATOM 2130 C CZ . PHE A 1 272 ? 61.244 23.789 135.002 1.00 3.70 ? 352 PHE N CZ 1 ATOM 2131 N N . SER A 1 273 ? 56.671 23.124 137.261 1.00 2.28 ? 353 SER N N 1 ATOM 2132 C CA . SER A 1 273 ? 56.563 24.476 137.761 1.00 4.27 ? 353 SER N CA 1 ATOM 2133 C C . SER A 1 273 ? 57.072 24.508 139.184 1.00 5.45 ? 353 SER N C 1 ATOM 2134 O O . SER A 1 273 ? 57.241 23.451 139.793 1.00 9.77 ? 353 SER N O 1 ATOM 2135 C CB . SER A 1 273 ? 55.154 24.962 137.786 1.00 3.70 ? 353 SER N CB 1 ATOM 2136 O OG . SER A 1 273 ? 54.242 24.045 138.349 1.00 2.00 ? 353 SER N OG 1 ATOM 2137 N N . TYR A 1 274 ? 57.385 25.675 139.729 1.00 4.77 ? 354 TYR N N 1 ATOM 2138 C CA . TYR A 1 274 ? 57.844 25.841 141.079 1.00 2.83 ? 354 TYR N CA 1 ATOM 2139 C C . TYR A 1 274 ? 56.888 26.865 141.586 1.00 2.06 ? 354 TYR N C 1 ATOM 2140 O O . TYR A 1 274 ? 56.916 28.033 141.205 1.00 2.00 ? 354 TYR N O 1 ATOM 2141 C CB . TYR A 1 274 ? 59.268 26.325 141.047 1.00 2.64 ? 354 TYR N CB 1 ATOM 2142 C CG . TYR A 1 274 ? 60.087 25.070 141.116 1.00 2.76 ? 354 TYR N CG 1 ATOM 2143 C CD1 . TYR A 1 274 ? 60.350 24.514 142.348 1.00 2.00 ? 354 TYR N CD1 1 ATOM 2144 C CD2 . TYR A 1 274 ? 60.502 24.423 139.964 1.00 2.50 ? 354 TYR N CD2 1 ATOM 2145 C CE1 . TYR A 1 274 ? 61.009 23.314 142.437 1.00 2.00 ? 354 TYR N CE1 1 ATOM 2146 C CE2 . TYR A 1 274 ? 61.161 23.215 140.064 1.00 2.62 ? 354 TYR N CE2 1 ATOM 2147 C CZ . TYR A 1 274 ? 61.392 22.687 141.299 1.00 2.00 ? 354 TYR N CZ 1 ATOM 2148 O OH . TYR A 1 274 ? 61.965 21.453 141.408 1.00 5.48 ? 354 TYR N OH 1 ATOM 2149 N N . LEU A 1 275 ? 55.986 26.418 142.428 1.00 3.00 ? 355 LEU N N 1 ATOM 2150 C CA . LEU A 1 275 ? 54.917 27.270 142.927 1.00 4.09 ? 355 LEU N CA 1 ATOM 2151 C C . LEU A 1 275 ? 55.248 27.697 144.356 1.00 3.27 ? 355 LEU N C 1 ATOM 2152 O O . LEU A 1 275 ? 55.177 26.856 145.258 1.00 4.13 ? 355 LEU N O 1 ATOM 2153 C CB . LEU A 1 275 ? 53.659 26.417 142.806 1.00 2.19 ? 355 LEU N CB 1 ATOM 2154 C CG . LEU A 1 275 ? 53.355 25.823 141.426 1.00 2.00 ? 355 LEU N CG 1 ATOM 2155 C CD1 . LEU A 1 275 ? 52.283 24.766 141.551 1.00 2.00 ? 355 LEU N CD1 1 ATOM 2156 C CD2 . LEU A 1 275 ? 52.834 26.888 140.499 1.00 3.34 ? 355 LEU N CD2 1 ATOM 2157 N N . ASP A 1 276 ? 55.648 28.950 144.617 1.00 3.15 ? 356 ASP N N 1 ATOM 2158 C CA . ASP A 1 276 ? 56.092 29.378 145.949 1.00 6.22 ? 356 ASP N CA 1 ATOM 2159 C C . ASP A 1 276 ? 55.692 30.826 146.279 1.00 9.72 ? 356 ASP N C 1 ATOM 2160 O O . ASP A 1 276 ? 56.388 31.590 146.973 1.00 11.82 ? 356 ASP N O 1 ATOM 2161 C CB . ASP A 1 276 ? 57.631 29.209 146.028 1.00 9.33 ? 356 ASP N CB 1 ATOM 2162 C CG . ASP A 1 276 ? 58.283 29.361 147.408 1.00 10.58 ? 356 ASP N CG 1 ATOM 2163 O OD1 . ASP A 1 276 ? 57.651 29.210 148.449 1.00 13.47 ? 356 ASP N OD1 1 ATOM 2164 O OD2 . ASP A 1 276 ? 59.465 29.657 147.446 1.00 9.04 ? 356 ASP N OD2 1 ATOM 2165 N N . GLY A 1 277 ? 54.513 31.274 145.836 1.00 8.93 ? 357 GLY N N 1 ATOM 2166 C CA . GLY A 1 277 ? 54.109 32.648 146.101 1.00 7.98 ? 357 GLY N CA 1 ATOM 2167 C C . GLY A 1 277 ? 54.869 33.544 145.138 1.00 7.90 ? 357 GLY N C 1 ATOM 2168 O O . GLY A 1 277 ? 54.939 33.219 143.957 1.00 7.46 ? 357 GLY N O 1 ATOM 2169 N N . VAL A 1 278 ? 55.547 34.592 145.595 1.00 8.39 ? 358 VAL N N 1 ATOM 2170 C CA . VAL A 1 278 ? 56.226 35.529 144.725 1.00 8.67 ? 358 VAL N CA 1 ATOM 2171 C C . VAL A 1 278 ? 57.269 34.758 143.951 1.00 9.34 ? 358 VAL N C 1 ATOM 2172 O O . VAL A 1 278 ? 57.357 34.836 142.745 1.00 10.16 ? 358 VAL N O 1 ATOM 2173 C CB . VAL A 1 278 ? 56.864 36.592 145.581 1.00 9.01 ? 358 VAL N CB 1 ATOM 2174 C CG1 . VAL A 1 278 ? 57.593 37.541 144.710 1.00 13.47 ? 358 VAL N CG1 1 ATOM 2175 C CG2 . VAL A 1 278 ? 55.816 37.410 146.305 1.00 11.27 ? 358 VAL N CG2 1 ATOM 2176 N N . ASN A 1 279 ? 58.029 33.943 144.657 1.00 11.28 ? 359 ASN N N 1 ATOM 2177 C CA . ASN A 1 279 ? 58.997 33.028 144.066 1.00 9.03 ? 359 ASN N CA 1 ATOM 2178 C C . ASN A 1 279 ? 58.401 31.890 143.237 1.00 8.78 ? 359 ASN N C 1 ATOM 2179 O O . ASN A 1 279 ? 58.771 30.736 143.437 1.00 11.34 ? 359 ASN N O 1 ATOM 2180 C CB . ASN A 1 279 ? 59.832 32.459 145.207 1.00 12.25 ? 359 ASN N CB 1 ATOM 2181 C CG . ASN A 1 279 ? 61.212 31.965 144.817 1.00 15.06 ? 359 ASN N CG 1 ATOM 2182 O OD1 . ASN A 1 279 ? 61.910 32.536 143.972 1.00 17.18 ? 359 ASN N OD1 1 ATOM 2183 N ND2 . ASN A 1 279 ? 61.699 30.950 145.521 1.00 15.47 ? 359 ASN N ND2 1 ATOM 2184 N N . THR A 1 280 ? 57.385 32.139 142.403 1.00 7.05 ? 360 THR N N 1 ATOM 2185 C CA . THR A 1 280 ? 56.885 31.128 141.508 1.00 5.25 ? 360 THR N CA 1 ATOM 2186 C C . THR A 1 280 ? 57.645 31.352 140.211 1.00 7.38 ? 360 THR N C 1 ATOM 2187 O O . THR A 1 280 ? 57.794 32.525 139.809 1.00 9.31 ? 360 THR N O 1 ATOM 2188 C CB . THR A 1 280 ? 55.365 31.309 141.221 1.00 5.74 ? 360 THR N CB 1 ATOM 2189 O OG1 . THR A 1 280 ? 54.683 30.983 142.422 1.00 8.71 ? 360 THR N OG1 1 ATOM 2190 C CG2 . THR A 1 280 ? 54.821 30.412 140.127 1.00 5.07 ? 360 THR N CG2 1 ATOM 2191 N N . TRP A 1 281 ? 58.080 30.244 139.576 1.00 5.79 ? 361 TRP N N 1 ATOM 2192 C CA . TRP A 1 281 ? 58.662 30.221 138.241 1.00 6.21 ? 361 TRP N CA 1 ATOM 2193 C C . TRP A 1 281 ? 58.002 29.049 137.569 1.00 3.93 ? 361 TRP N C 1 ATOM 2194 O O . TRP A 1 281 ? 57.792 28.044 138.227 1.00 5.04 ? 361 TRP N O 1 ATOM 2195 C CB . TRP A 1 281 ? 60.163 29.939 138.183 1.00 4.89 ? 361 TRP N CB 1 ATOM 2196 C CG . TRP A 1 281 ? 61.092 31.088 138.554 1.00 3.04 ? 361 TRP N CG 1 ATOM 2197 C CD1 . TRP A 1 281 ? 61.204 31.491 139.843 1.00 4.06 ? 361 TRP N CD1 1 ATOM 2198 C CD2 . TRP A 1 281 ? 61.899 31.785 137.700 1.00 2.00 ? 361 TRP N CD2 1 ATOM 2199 N NE1 . TRP A 1 281 ? 62.092 32.430 139.809 1.00 4.03 ? 361 TRP N NE1 1 ATOM 2200 C CE2 . TRP A 1 281 ? 62.535 32.648 138.559 1.00 3.29 ? 361 TRP N CE2 1 ATOM 2201 C CE3 . TRP A 1 281 ? 62.193 31.837 136.358 1.00 2.56 ? 361 TRP N CE3 1 ATOM 2202 C CZ2 . TRP A 1 281 ? 63.468 33.572 138.101 1.00 2.88 ? 361 TRP N CZ2 1 ATOM 2203 C CZ3 . TRP A 1 281 ? 63.120 32.753 135.908 1.00 2.36 ? 361 TRP N CZ3 1 ATOM 2204 C CH2 . TRP A 1 281 ? 63.754 33.615 136.765 1.00 2.00 ? 361 TRP N CH2 1 ATOM 2205 N N . LEU A 1 282 ? 57.657 29.218 136.288 1.00 4.00 ? 362 LEU N N 1 ATOM 2206 C CA . LEU A 1 282 ? 56.957 28.332 135.325 1.00 5.82 ? 362 LEU N CA 1 ATOM 2207 C C . LEU A 1 282 ? 57.855 28.097 134.107 1.00 3.41 ? 362 LEU N C 1 ATOM 2208 O O . LEU A 1 282 ? 58.680 28.939 133.737 1.00 5.38 ? 362 LEU N O 1 ATOM 2209 C CB . LEU A 1 282 ? 55.664 28.942 134.698 1.00 4.83 ? 362 LEU N CB 1 ATOM 2210 C CG . LEU A 1 282 ? 54.724 29.735 135.532 1.00 2.86 ? 362 LEU N CG 1 ATOM 2211 C CD1 . LEU A 1 282 ? 53.488 30.132 134.767 1.00 2.00 ? 362 LEU N CD1 1 ATOM 2212 C CD2 . LEU A 1 282 ? 54.368 28.865 136.710 1.00 3.90 ? 362 LEU N CD2 1 ATOM 2213 N N . GLY A 1 283 ? 57.606 27.042 133.368 1.00 5.15 ? 363 GLY N N 1 ATOM 2214 C CA . GLY A 1 283 ? 58.390 26.823 132.180 1.00 6.18 ? 363 GLY N CA 1 ATOM 2215 C C . GLY A 1 283 ? 57.490 26.083 131.240 1.00 4.82 ? 363 GLY N C 1 ATOM 2216 O O . GLY A 1 283 ? 56.673 25.223 131.671 1.00 5.70 ? 363 GLY N O 1 ATOM 2217 N N . ARG A 1 284 ? 57.670 26.619 130.012 1.00 4.70 ? 364 ARG N N 1 ATOM 2218 C CA . ARG A 1 284 ? 56.980 26.280 128.754 1.00 2.85 ? 364 ARG N CA 1 ATOM 2219 C C . ARG A 1 284 ? 57.966 26.229 127.596 1.00 4.67 ? 364 ARG N C 1 ATOM 2220 O O . ARG A 1 284 ? 59.077 26.793 127.706 1.00 6.14 ? 364 ARG N O 1 ATOM 2221 C CB . ARG A 1 284 ? 55.878 27.342 128.412 1.00 3.51 ? 364 ARG N CB 1 ATOM 2222 C CG . ARG A 1 284 ? 56.082 28.768 128.912 1.00 4.10 ? 364 ARG N CG 1 ATOM 2223 C CD . ARG A 1 284 ? 56.136 29.832 127.822 1.00 2.44 ? 364 ARG N CD 1 ATOM 2224 N NE . ARG A 1 284 ? 54.816 30.322 127.450 1.00 4.24 ? 364 ARG N NE 1 ATOM 2225 C CZ . ARG A 1 284 ? 54.518 31.630 127.420 1.00 4.11 ? 364 ARG N CZ 1 ATOM 2226 N NH1 . ARG A 1 284 ? 55.222 32.538 128.037 1.00 3.71 ? 364 ARG N NH1 1 ATOM 2227 N NH2 . ARG A 1 284 ? 53.376 32.072 126.947 1.00 2.00 ? 364 ARG N NH2 1 ATOM 2228 N N . THR A 1 285 ? 57.647 25.557 126.497 1.00 5.49 ? 365 THR N N 1 ATOM 2229 C CA . THR A 1 285 ? 58.451 25.663 125.314 1.00 4.68 ? 365 THR N CA 1 ATOM 2230 C C . THR A 1 285 ? 58.338 27.075 124.783 1.00 6.03 ? 365 THR N C 1 ATOM 2231 O O . THR A 1 285 ? 57.400 27.772 125.197 1.00 5.84 ? 365 THR N O 1 ATOM 2232 C CB . THR A 1 285 ? 57.954 24.736 124.291 1.00 2.87 ? 365 THR N CB 1 ATOM 2233 O OG1 . THR A 1 285 ? 56.572 24.919 124.199 1.00 2.00 ? 365 THR N OG1 1 ATOM 2234 C CG2 . THR A 1 285 ? 58.284 23.336 124.653 1.00 2.75 ? 365 THR N CG2 1 ATOM 2235 N N . ILE A 1 286 ? 59.205 27.580 123.882 1.00 7.36 ? 366 ILE N N 1 ATOM 2236 C CA . ILE A 1 286 ? 58.952 28.932 123.392 1.00 6.94 ? 366 ILE N CA 1 ATOM 2237 C C . ILE A 1 286 ? 57.860 28.942 122.290 1.00 9.31 ? 366 ILE N C 1 ATOM 2238 O O . ILE A 1 286 ? 57.113 29.920 122.090 1.00 12.88 ? 366 ILE N O 1 ATOM 2239 C CB . ILE A 1 286 ? 60.288 29.517 122.915 1.00 2.64 ? 366 ILE N CB 1 ATOM 2240 C CG1 . ILE A 1 286 ? 61.126 29.854 124.153 1.00 3.04 ? 366 ILE N CG1 1 ATOM 2241 C CG2 . ILE A 1 286 ? 60.063 30.759 122.073 1.00 4.85 ? 366 ILE N CG2 1 ATOM 2242 C CD1 . ILE A 1 286 ? 62.547 30.447 123.871 1.00 3.27 ? 366 ILE N CD1 1 ATOM 2243 N N . SER A 1 287 ? 57.761 27.832 121.569 1.00 10.35 ? 367 SER N N 1 ATOM 2244 C CA . SER A 1 287 ? 56.845 27.691 120.465 1.00 11.68 ? 367 SER N CA 1 ATOM 2245 C C . SER A 1 287 ? 55.508 27.273 120.964 1.00 8.02 ? 367 SER N C 1 ATOM 2246 O O . SER A 1 287 ? 55.431 26.405 121.818 1.00 9.41 ? 367 SER N O 1 ATOM 2247 C CB . SER A 1 287 ? 57.355 26.644 119.522 1.00 11.70 ? 367 SER N CB 1 ATOM 2248 O OG . SER A 1 287 ? 56.426 26.239 118.537 1.00 14.41 ? 367 SER N OG 1 ATOM 2249 N N . ILE A 1 288 ? 54.451 27.826 120.415 1.00 7.99 ? 368 ILE N N 1 ATOM 2250 C CA . ILE A 1 288 ? 53.140 27.369 120.847 1.00 7.14 ? 368 ILE N CA 1 ATOM 2251 C C . ILE A 1 288 ? 52.667 26.093 120.130 1.00 5.57 ? 368 ILE N C 1 ATOM 2252 O O . ILE A 1 288 ? 51.761 25.379 120.559 1.00 5.66 ? 368 ILE N O 1 ATOM 2253 C CB . ILE A 1 288 ? 52.061 28.492 120.644 1.00 4.85 ? 368 ILE N CB 1 ATOM 2254 C CG1 . ILE A 1 288 ? 52.051 28.953 119.178 1.00 4.10 ? 368 ILE N CG1 1 ATOM 2255 C CG2 . ILE A 1 288 ? 52.328 29.627 121.599 1.00 2.11 ? 368 ILE N CG2 1 ATOM 2256 C CD1 . ILE A 1 288 ? 50.672 28.924 118.512 1.00 6.47 ? 368 ILE N CD1 1 ATOM 2257 N N . ALA A 1 289 ? 53.235 25.835 118.973 1.00 5.78 ? 369 ALA N N 1 ATOM 2258 C CA . ALA A 1 289 ? 52.791 24.714 118.212 1.00 5.82 ? 369 ALA N CA 1 ATOM 2259 C C . ALA A 1 289 ? 53.675 23.522 118.430 1.00 6.05 ? 369 ALA N C 1 ATOM 2260 O O . ALA A 1 289 ? 53.190 22.399 118.305 1.00 7.39 ? 369 ALA N O 1 ATOM 2261 C CB . ALA A 1 289 ? 52.831 24.992 116.748 1.00 6.13 ? 369 ALA N CB 1 ATOM 2262 N N . SER A 1 290 ? 54.952 23.724 118.711 1.00 5.32 ? 370 SER N N 1 ATOM 2263 C CA . SER A 1 290 ? 55.878 22.624 118.718 1.00 6.31 ? 370 SER N CA 1 ATOM 2264 C C . SER A 1 290 ? 56.792 22.577 119.914 1.00 6.42 ? 370 SER N C 1 ATOM 2265 O O . SER A 1 290 ? 56.802 23.540 120.680 1.00 8.17 ? 370 SER N O 1 ATOM 2266 C CB . SER A 1 290 ? 56.703 22.677 117.449 1.00 5.84 ? 370 SER N CB 1 ATOM 2267 O OG . SER A 1 290 ? 55.865 22.688 116.319 1.00 3.22 ? 370 SER N OG 1 ATOM 2268 N N . ARG A 1 291 ? 57.594 21.513 120.045 1.00 5.27 ? 371 ARG N N 1 ATOM 2269 C CA . ARG A 1 291 ? 58.524 21.384 121.132 1.00 2.91 ? 371 ARG N CA 1 ATOM 2270 C C . ARG A 1 291 ? 59.855 21.914 120.654 1.00 4.21 ? 371 ARG N C 1 ATOM 2271 O O . ARG A 1 291 ? 60.823 21.190 120.371 1.00 8.07 ? 371 ARG N O 1 ATOM 2272 C CB . ARG A 1 291 ? 58.628 19.935 121.535 1.00 3.73 ? 371 ARG N CB 1 ATOM 2273 C CG . ARG A 1 291 ? 57.338 19.570 122.219 1.00 2.00 ? 371 ARG N CG 1 ATOM 2274 C CD . ARG A 1 291 ? 57.360 18.090 122.218 1.00 2.01 ? 371 ARG N CD 1 ATOM 2275 N NE . ARG A 1 291 ? 56.129 17.565 122.748 1.00 4.29 ? 371 ARG N NE 1 ATOM 2276 C CZ . ARG A 1 291 ? 55.893 16.248 122.857 1.00 5.02 ? 371 ARG N CZ 1 ATOM 2277 N NH1 . ARG A 1 291 ? 56.756 15.363 122.381 1.00 3.43 ? 371 ARG N NH1 1 ATOM 2278 N NH2 . ARG A 1 291 ? 54.751 15.797 123.398 1.00 5.53 ? 371 ARG N NH2 1 ATOM 2279 N N . SER A 1 292 ? 59.863 23.220 120.475 1.00 2.00 ? 372 SER N N 1 ATOM 2280 C CA . SER A 1 292 ? 61.113 23.852 120.209 1.00 2.77 ? 372 SER N CA 1 ATOM 2281 C C . SER A 1 292 ? 61.222 24.940 121.257 1.00 5.41 ? 372 SER N C 1 ATOM 2282 O O . SER A 1 292 ? 60.206 25.525 121.701 1.00 5.17 ? 372 SER N O 1 ATOM 2283 C CB . SER A 1 292 ? 61.149 24.421 118.789 1.00 3.97 ? 372 SER N CB 1 ATOM 2284 O OG . SER A 1 292 ? 60.025 25.143 118.296 1.00 3.19 ? 372 SER N OG 1 ATOM 2285 N N . GLY A 1 293 ? 62.470 25.180 121.679 1.00 6.16 ? 373 GLY N N 1 ATOM 2286 C CA . GLY A 1 293 ? 62.781 26.140 122.712 1.00 3.86 ? 373 GLY N CA 1 ATOM 2287 C C . GLY A 1 293 ? 62.201 25.714 124.036 1.00 2.00 ? 373 GLY N C 1 ATOM 2288 O O . GLY A 1 293 ? 61.322 24.866 124.095 1.00 2.21 ? 373 GLY N O 1 ATOM 2289 N N . TYR A 1 294 ? 62.696 26.269 125.118 1.00 4.08 ? 374 TYR N N 1 ATOM 2290 C CA . TYR A 1 294 ? 62.274 25.970 126.472 1.00 4.34 ? 374 TYR N CA 1 ATOM 2291 C C . TYR A 1 294 ? 62.755 27.224 127.174 1.00 5.67 ? 374 TYR N C 1 ATOM 2292 O O . TYR A 1 294 ? 63.913 27.674 126.969 1.00 7.72 ? 374 TYR N O 1 ATOM 2293 C CB . TYR A 1 294 ? 63.021 24.789 127.030 1.00 2.66 ? 374 TYR N CB 1 ATOM 2294 C CG . TYR A 1 294 ? 62.290 24.328 128.270 1.00 3.76 ? 374 TYR N CG 1 ATOM 2295 C CD1 . TYR A 1 294 ? 61.167 23.535 128.109 1.00 3.27 ? 374 TYR N CD1 1 ATOM 2296 C CD2 . TYR A 1 294 ? 62.677 24.766 129.529 1.00 2.89 ? 374 TYR N CD2 1 ATOM 2297 C CE1 . TYR A 1 294 ? 60.407 23.202 129.193 1.00 2.00 ? 374 TYR N CE1 1 ATOM 2298 C CE2 . TYR A 1 294 ? 61.898 24.439 130.614 1.00 2.76 ? 374 TYR N CE2 1 ATOM 2299 C CZ . TYR A 1 294 ? 60.767 23.659 130.443 1.00 2.57 ? 374 TYR N CZ 1 ATOM 2300 O OH . TYR A 1 294 ? 59.919 23.432 131.520 1.00 2.00 ? 374 TYR N OH 1 ATOM 2301 N N . GLU A 1 295 ? 61.897 27.771 128.026 1.00 2.99 ? 375 GLU N N 1 ATOM 2302 C CA . GLU A 1 295 ? 62.223 28.991 128.740 1.00 3.72 ? 375 GLU N CA 1 ATOM 2303 C C . GLU A 1 295 ? 61.597 28.957 130.103 1.00 4.14 ? 375 GLU N C 1 ATOM 2304 O O . GLU A 1 295 ? 60.595 28.219 130.273 1.00 5.29 ? 375 GLU N O 1 ATOM 2305 C CB . GLU A 1 295 ? 61.719 30.200 127.965 1.00 5.07 ? 375 GLU N CB 1 ATOM 2306 C CG . GLU A 1 295 ? 60.219 30.397 127.740 1.00 3.32 ? 375 GLU N CG 1 ATOM 2307 C CD . GLU A 1 295 ? 59.845 31.736 127.107 1.00 2.70 ? 375 GLU N CD 1 ATOM 2308 O OE1 . GLU A 1 295 ? 60.674 32.653 126.934 1.00 2.45 ? 375 GLU N OE1 1 ATOM 2309 O OE2 . GLU A 1 295 ? 58.672 31.858 126.790 1.00 2.00 ? 375 GLU N OE2 1 ATOM 2310 N N . MET A 1 296 ? 62.199 29.722 131.027 1.00 3.21 ? 376 MET N N 1 ATOM 2311 C CA . MET A 1 296 ? 61.730 29.762 132.411 1.00 4.00 ? 376 MET N CA 1 ATOM 2312 C C . MET A 1 296 ? 61.122 31.125 132.671 1.00 3.14 ? 376 MET N C 1 ATOM 2313 O O . MET A 1 296 ? 61.714 32.112 132.211 1.00 4.15 ? 376 MET N O 1 ATOM 2314 C CB . MET A 1 296 ? 62.859 29.584 133.423 1.00 2.00 ? 376 MET N CB 1 ATOM 2315 C CG . MET A 1 296 ? 63.370 28.200 133.443 1.00 2.00 ? 376 MET N CG 1 ATOM 2316 S SD . MET A 1 296 ? 61.977 27.087 133.665 1.00 2.00 ? 376 MET N SD 1 ATOM 2317 C CE . MET A 1 296 ? 61.742 27.167 135.400 1.00 2.08 ? 376 MET N CE 1 ATOM 2318 N N . LEU A 1 297 ? 60.016 31.289 133.407 1.00 2.00 ? 377 LEU N N 1 ATOM 2319 C CA . LEU A 1 297 ? 59.488 32.608 133.601 1.00 4.15 ? 377 LEU N CA 1 ATOM 2320 C C . LEU A 1 297 ? 59.147 32.712 135.036 1.00 2.80 ? 377 LEU N C 1 ATOM 2321 O O . LEU A 1 297 ? 58.668 31.753 135.606 1.00 3.17 ? 377 LEU N O 1 ATOM 2322 C CB . LEU A 1 297 ? 58.219 32.846 132.847 1.00 2.80 ? 377 LEU N CB 1 ATOM 2323 C CG . LEU A 1 297 ? 58.187 32.693 131.334 1.00 3.15 ? 377 LEU N CG 1 ATOM 2324 C CD1 . LEU A 1 297 ? 56.770 32.868 130.845 1.00 3.04 ? 377 LEU N CD1 1 ATOM 2325 C CD2 . LEU A 1 297 ? 59.055 33.743 130.672 1.00 5.72 ? 377 LEU N CD2 1 ATOM 2326 N N . LYS A 1 298 ? 59.516 33.823 135.652 1.00 3.59 ? 378 LYS N N 1 ATOM 2327 C CA . LYS A 1 298 ? 59.081 34.183 136.992 1.00 3.42 ? 378 LYS N CA 1 ATOM 2328 C C . LYS A 1 298 ? 57.771 34.884 136.774 1.00 6.64 ? 378 LYS N C 1 ATOM 2329 O O . LYS A 1 298 ? 57.675 35.836 135.997 1.00 7.08 ? 378 LYS N O 1 ATOM 2330 C CB . LYS A 1 298 ? 60.010 35.129 137.634 1.00 3.08 ? 378 LYS N CB 1 ATOM 2331 C CG . LYS A 1 298 ? 59.659 35.458 139.044 1.00 6.72 ? 378 LYS N CG 1 ATOM 2332 C CD . LYS A 1 298 ? 60.940 35.987 139.656 1.00 9.08 ? 378 LYS N CD 1 ATOM 2333 C CE . LYS A 1 298 ? 60.605 36.669 140.961 1.00 10.70 ? 378 LYS N CE 1 ATOM 2334 N NZ . LYS A 1 298 ? 59.891 37.928 140.680 1.00 16.48 ? 378 LYS N NZ 1 ATOM 2335 N N . VAL A 1 299 ? 56.751 34.307 137.375 1.00 5.79 ? 379 VAL N N 1 ATOM 2336 C CA . VAL A 1 299 ? 55.370 34.768 137.294 1.00 6.41 ? 379 VAL N CA 1 ATOM 2337 C C . VAL A 1 299 ? 54.879 34.746 138.749 1.00 7.35 ? 379 VAL N C 1 ATOM 2338 O O . VAL A 1 299 ? 54.279 33.751 139.188 1.00 8.94 ? 379 VAL N O 1 ATOM 2339 C CB . VAL A 1 299 ? 54.528 33.781 136.432 1.00 7.49 ? 379 VAL N CB 1 ATOM 2340 C CG1 . VAL A 1 299 ? 53.119 34.252 136.373 1.00 6.05 ? 379 VAL N CG1 1 ATOM 2341 C CG2 . VAL A 1 299 ? 55.068 33.658 135.033 1.00 10.17 ? 379 VAL N CG2 1 ATOM 2342 N N . PRO A 1 300 ? 55.120 35.761 139.570 1.00 9.89 ? 380 PRO N N 1 ATOM 2343 C CA . PRO A 1 300 ? 54.726 35.756 140.964 1.00 9.43 ? 380 PRO N CA 1 ATOM 2344 C C . PRO A 1 300 ? 53.268 35.353 141.144 1.00 10.87 ? 380 PRO N C 1 ATOM 2345 O O . PRO A 1 300 ? 52.400 35.847 140.422 1.00 14.78 ? 380 PRO N O 1 ATOM 2346 C CB . PRO A 1 300 ? 55.076 37.147 141.359 1.00 6.20 ? 380 PRO N CB 1 ATOM 2347 C CG . PRO A 1 300 ? 56.275 37.479 140.515 1.00 6.65 ? 380 PRO N CG 1 ATOM 2348 C CD . PRO A 1 300 ? 55.749 37.018 139.183 1.00 8.21 ? 380 PRO N CD 1 ATOM 2349 N N . ASN A 1 301 ? 53.027 34.370 142.028 1.00 12.12 ? 381 ASN N N 1 ATOM 2350 C CA . ASN A 1 301 ? 51.708 33.832 142.357 1.00 13.18 ? 381 ASN N CA 1 ATOM 2351 C C . ASN A 1 301 ? 50.810 33.167 141.335 1.00 14.25 ? 381 ASN N C 1 ATOM 2352 O O . ASN A 1 301 ? 49.572 33.093 141.488 1.00 12.10 ? 381 ASN N O 1 ATOM 2353 C CB . ASN A 1 301 ? 50.923 34.915 142.999 1.00 17.89 ? 381 ASN N CB 1 ATOM 2354 C CG . ASN A 1 301 ? 51.324 35.055 144.440 1.00 20.38 ? 381 ASN N CG 1 ATOM 2355 O OD1 . ASN A 1 301 ? 51.735 36.116 144.897 1.00 22.96 ? 381 ASN N OD1 1 ATOM 2356 N ND2 . ASN A 1 301 ? 51.230 33.992 145.238 1.00 21.93 ? 381 ASN N ND2 1 ATOM 2357 N N . ALA A 1 302 ? 51.464 32.533 140.363 1.00 9.15 ? 382 ALA N N 1 ATOM 2358 C CA . ALA A 1 302 ? 50.784 32.005 139.203 1.00 7.81 ? 382 ALA N CA 1 ATOM 2359 C C . ALA A 1 302 ? 49.740 30.916 139.434 1.00 10.04 ? 382 ALA N C 1 ATOM 2360 O O . ALA A 1 302 ? 48.887 30.633 138.576 1.00 11.24 ? 382 ALA N O 1 ATOM 2361 C CB . ALA A 1 302 ? 51.802 31.478 138.268 1.00 6.66 ? 382 ALA N CB 1 ATOM 2362 N N . LEU A 1 303 ? 49.816 30.308 140.621 1.00 10.44 ? 383 LEU N N 1 ATOM 2363 C CA . LEU A 1 303 ? 48.962 29.224 141.022 1.00 9.28 ? 383 LEU N CA 1 ATOM 2364 C C . LEU A 1 303 ? 47.637 29.886 141.248 1.00 11.99 ? 383 LEU N C 1 ATOM 2365 O O . LEU A 1 303 ? 46.704 29.527 140.557 1.00 15.22 ? 383 LEU N O 1 ATOM 2366 C CB . LEU A 1 303 ? 49.468 28.538 142.346 1.00 6.47 ? 383 LEU N CB 1 ATOM 2367 C CG . LEU A 1 303 ? 48.493 27.602 143.094 1.00 3.01 ? 383 LEU N CG 1 ATOM 2368 C CD1 . LEU A 1 303 ? 47.986 26.593 142.107 1.00 4.64 ? 383 LEU N CD1 1 ATOM 2369 C CD2 . LEU A 1 303 ? 49.147 26.874 144.267 1.00 3.50 ? 383 LEU N CD2 1 ATOM 2370 N N . THR A 1 304 ? 47.606 30.890 142.125 1.00 14.83 ? 384 THR N N 1 ATOM 2371 C CA . THR A 1 304 ? 46.439 31.584 142.602 1.00 13.48 ? 384 THR N CA 1 ATOM 2372 C C . THR A 1 304 ? 45.959 32.840 141.915 1.00 17.65 ? 384 THR N C 1 ATOM 2373 O O . THR A 1 304 ? 44.748 33.070 141.965 1.00 18.76 ? 384 THR N O 1 ATOM 2374 C CB . THR A 1 304 ? 46.661 31.926 144.070 1.00 10.74 ? 384 THR N CB 1 ATOM 2375 O OG1 . THR A 1 304 ? 48.054 32.220 144.279 1.00 11.84 ? 384 THR N OG1 1 ATOM 2376 C CG2 . THR A 1 304 ? 46.182 30.814 144.944 1.00 8.02 ? 384 THR N CG2 1 ATOM 2377 N N . ASP A 1 305 ? 46.789 33.715 141.324 1.00 20.06 ? 385 ASP N N 1 ATOM 2378 C CA . ASP A 1 305 ? 46.251 34.969 140.788 1.00 20.82 ? 385 ASP N CA 1 ATOM 2379 C C . ASP A 1 305 ? 45.950 34.809 139.308 1.00 21.94 ? 385 ASP N C 1 ATOM 2380 O O . ASP A 1 305 ? 46.886 34.581 138.523 1.00 24.38 ? 385 ASP N O 1 ATOM 2381 C CB . ASP A 1 305 ? 47.232 36.136 140.947 1.00 20.84 ? 385 ASP N CB 1 ATOM 2382 C CG . ASP A 1 305 ? 46.768 37.446 140.281 1.00 23.26 ? 385 ASP N CG 1 ATOM 2383 O OD1 . ASP A 1 305 ? 47.049 37.674 139.098 1.00 22.62 ? 385 ASP N OD1 1 ATOM 2384 O OD2 . ASP A 1 305 ? 46.108 38.244 140.950 1.00 25.01 ? 385 ASP N OD2 1 ATOM 2385 N N . ASP A 1 306 ? 44.726 35.059 138.831 1.00 21.22 ? 386 ASP N N 1 ATOM 2386 C CA . ASP A 1 306 ? 44.469 34.757 137.425 1.00 18.33 ? 386 ASP N CA 1 ATOM 2387 C C . ASP A 1 306 ? 44.667 35.810 136.377 1.00 17.87 ? 386 ASP N C 1 ATOM 2388 O O . ASP A 1 306 ? 44.055 35.698 135.322 1.00 18.35 ? 386 ASP N O 1 ATOM 2389 C CB . ASP A 1 306 ? 43.056 34.168 137.253 1.00 18.84 ? 386 ASP N CB 1 ATOM 2390 C CG . ASP A 1 306 ? 41.879 34.943 137.794 1.00 21.18 ? 386 ASP N CG 1 ATOM 2391 O OD1 . ASP A 1 306 ? 42.066 35.847 138.614 1.00 22.05 ? 386 ASP N OD1 1 ATOM 2392 O OD2 . ASP A 1 306 ? 40.769 34.612 137.371 1.00 21.46 ? 386 ASP N OD2 1 ATOM 2393 N N . LYS A 1 307 ? 45.545 36.772 136.687 1.00 17.70 ? 387 LYS N N 1 ATOM 2394 C CA . LYS A 1 307 ? 46.052 37.746 135.741 1.00 18.39 ? 387 LYS N CA 1 ATOM 2395 C C . LYS A 1 307 ? 47.579 37.871 135.921 1.00 19.20 ? 387 LYS N C 1 ATOM 2396 O O . LYS A 1 307 ? 48.180 38.905 135.629 1.00 19.69 ? 387 LYS N O 1 ATOM 2397 C CB . LYS A 1 307 ? 45.416 39.090 135.976 1.00 19.86 ? 387 LYS N CB 1 ATOM 2398 C CG . LYS A 1 307 ? 43.912 39.178 136.030 1.00 22.54 ? 387 LYS N CG 1 ATOM 2399 C CD . LYS A 1 307 ? 43.512 39.015 137.493 1.00 25.50 ? 387 LYS N CD 1 ATOM 2400 C CE . LYS A 1 307 ? 42.007 39.220 137.711 1.00 30.32 ? 387 LYS N CE 1 ATOM 2401 N NZ . LYS A 1 307 ? 41.801 39.849 139.015 1.00 34.74 ? 387 LYS N NZ 1 ATOM 2402 N N . SER A 1 308 ? 48.316 36.852 136.401 1.00 19.76 ? 388 SER N N 1 ATOM 2403 C CA . SER A 1 308 ? 49.756 36.954 136.623 1.00 18.34 ? 388 SER N CA 1 ATOM 2404 C C . SER A 1 308 ? 50.514 36.751 135.337 1.00 19.49 ? 388 SER N C 1 ATOM 2405 O O . SER A 1 308 ? 50.420 35.701 134.704 1.00 20.17 ? 388 SER N O 1 ATOM 2406 C CB . SER A 1 308 ? 50.229 35.917 137.663 1.00 18.53 ? 388 SER N CB 1 ATOM 2407 O OG . SER A 1 308 ? 49.508 34.702 137.643 1.00 16.82 ? 388 SER N OG 1 ATOM 2408 N N . LYS A 1 309 ? 51.185 37.805 134.928 1.00 18.48 ? 389 LYS N N 1 ATOM 2409 C CA . LYS A 1 309 ? 51.978 37.837 133.725 1.00 18.96 ? 389 LYS N CA 1 ATOM 2410 C C . LYS A 1 309 ? 53.421 37.814 134.222 1.00 16.72 ? 389 LYS N C 1 ATOM 2411 O O . LYS A 1 309 ? 53.644 38.186 135.377 1.00 20.21 ? 389 LYS N O 1 ATOM 2412 C CB . LYS A 1 309 ? 51.663 39.134 132.960 1.00 22.17 ? 389 LYS N CB 1 ATOM 2413 C CG . LYS A 1 309 ? 50.218 39.376 132.459 1.00 25.29 ? 389 LYS N CG 1 ATOM 2414 C CD . LYS A 1 309 ? 49.782 38.212 131.543 1.00 30.68 ? 389 LYS N CD 1 ATOM 2415 C CE . LYS A 1 309 ? 49.109 38.575 130.222 1.00 33.10 ? 389 LYS N CE 1 ATOM 2416 N NZ . LYS A 1 309 ? 49.199 37.413 129.369 1.00 33.57 ? 389 LYS N NZ 1 ATOM 2417 N N . PRO A 1 310 ? 54.442 37.379 133.485 1.00 12.01 ? 390 PRO N N 1 ATOM 2418 C CA . PRO A 1 310 ? 55.773 37.194 134.021 1.00 11.22 ? 390 PRO N CA 1 ATOM 2419 C C . PRO A 1 310 ? 56.555 38.446 134.370 1.00 11.50 ? 390 PRO N C 1 ATOM 2420 O O . PRO A 1 310 ? 56.448 39.424 133.638 1.00 11.75 ? 390 PRO N O 1 ATOM 2421 C CB . PRO A 1 310 ? 56.413 36.334 132.972 1.00 12.63 ? 390 PRO N CB 1 ATOM 2422 C CG . PRO A 1 310 ? 55.740 36.753 131.707 1.00 11.83 ? 390 PRO N CG 1 ATOM 2423 C CD . PRO A 1 310 ? 54.313 36.795 132.166 1.00 10.97 ? 390 PRO N CD 1 ATOM 2424 N N . THR A 1 311 ? 57.333 38.460 135.443 1.00 9.99 ? 391 THR N N 1 ATOM 2425 C CA . THR A 1 311 ? 58.203 39.570 135.724 1.00 7.63 ? 391 THR N CA 1 ATOM 2426 C C . THR A 1 311 ? 59.672 39.357 135.420 1.00 7.11 ? 391 THR N C 1 ATOM 2427 O O . THR A 1 311 ? 60.403 40.332 135.269 1.00 11.70 ? 391 THR N O 1 ATOM 2428 C CB . THR A 1 311 ? 58.076 40.002 137.182 1.00 5.89 ? 391 THR N CB 1 ATOM 2429 O OG1 . THR A 1 311 ? 58.251 38.960 138.130 1.00 5.28 ? 391 THR N OG1 1 ATOM 2430 C CG2 . THR A 1 311 ? 56.711 40.623 137.260 1.00 8.66 ? 391 THR N CG2 1 ATOM 2431 N N . GLN A 1 312 ? 60.233 38.168 135.314 1.00 7.14 ? 392 GLN N N 1 ATOM 2432 C CA . GLN A 1 312 ? 61.640 38.004 134.999 1.00 6.69 ? 392 GLN N CA 1 ATOM 2433 C C . GLN A 1 312 ? 61.628 36.735 134.178 1.00 5.35 ? 392 GLN N C 1 ATOM 2434 O O . GLN A 1 312 ? 60.676 35.958 134.304 1.00 2.59 ? 392 GLN N O 1 ATOM 2435 C CB . GLN A 1 312 ? 62.467 37.767 136.248 1.00 6.89 ? 392 GLN N CB 1 ATOM 2436 C CG . GLN A 1 312 ? 63.877 38.215 136.097 1.00 10.21 ? 392 GLN N CG 1 ATOM 2437 C CD . GLN A 1 312 ? 64.839 37.637 137.100 1.00 13.06 ? 392 GLN N CD 1 ATOM 2438 O OE1 . GLN A 1 312 ? 65.884 37.119 136.719 1.00 16.33 ? 392 GLN N OE1 1 ATOM 2439 N NE2 . GLN A 1 312 ? 64.585 37.699 138.397 1.00 13.14 ? 392 GLN N NE2 1 ATOM 2440 N N . GLY A 1 313 ? 62.618 36.464 133.335 1.00 6.51 ? 394 GLY N N 1 ATOM 2441 C CA . GLY A 1 313 ? 62.636 35.213 132.580 1.00 6.11 ? 394 GLY N CA 1 ATOM 2442 C C . GLY A 1 313 ? 64.055 34.712 132.357 1.00 6.33 ? 394 GLY N C 1 ATOM 2443 O O . GLY A 1 313 ? 65.038 35.305 132.841 1.00 8.18 ? 394 GLY N O 1 ATOM 2444 N N . GLN A 1 314 ? 64.186 33.642 131.585 1.00 5.09 ? 395 GLN N N 1 ATOM 2445 C CA . GLN A 1 314 ? 65.482 33.036 131.321 1.00 8.14 ? 395 GLN N CA 1 ATOM 2446 C C . GLN A 1 314 ? 65.370 32.041 130.175 1.00 9.79 ? 395 GLN N C 1 ATOM 2447 O O . GLN A 1 314 ? 64.556 31.098 130.214 1.00 11.86 ? 395 GLN N O 1 ATOM 2448 C CB . GLN A 1 314 ? 66.025 32.292 132.548 1.00 7.35 ? 395 GLN N CB 1 ATOM 2449 C CG . GLN A 1 314 ? 67.537 32.449 132.445 1.00 7.30 ? 395 GLN N CG 1 ATOM 2450 C CD . GLN A 1 314 ? 68.459 31.820 133.459 1.00 5.77 ? 395 GLN N CD 1 ATOM 2451 O OE1 . GLN A 1 314 ? 69.194 30.921 133.091 1.00 10.01 ? 395 GLN N OE1 1 ATOM 2452 N NE2 . GLN A 1 314 ? 68.544 32.224 134.700 1.00 5.66 ? 395 GLN N NE2 1 ATOM 2453 N N . THR A 1 315 ? 66.130 32.302 129.113 1.00 9.49 ? 396 THR N N 1 ATOM 2454 C CA . THR A 1 315 ? 66.102 31.365 128.024 1.00 10.43 ? 396 THR N CA 1 ATOM 2455 C C . THR A 1 315 ? 67.143 30.278 128.184 1.00 10.14 ? 396 THR N C 1 ATOM 2456 O O . THR A 1 315 ? 68.346 30.510 128.381 1.00 10.47 ? 396 THR N O 1 ATOM 2457 C CB . THR A 1 315 ? 66.291 32.126 126.724 1.00 11.73 ? 396 THR N CB 1 ATOM 2458 O OG1 . THR A 1 315 ? 65.234 33.105 126.678 1.00 11.33 ? 396 THR N OG1 1 ATOM 2459 C CG2 . THR A 1 315 ? 66.177 31.236 125.502 1.00 10.31 ? 396 THR N CG2 1 ATOM 2460 N N . ILE A 1 316 ? 66.506 29.108 128.172 1.00 9.44 ? 397 ILE N N 1 ATOM 2461 C CA . ILE A 1 316 ? 67.173 27.861 128.375 1.00 9.82 ? 397 ILE N CA 1 ATOM 2462 C C . ILE A 1 316 ? 67.536 27.190 127.047 1.00 9.04 ? 397 ILE N C 1 ATOM 2463 O O . ILE A 1 316 ? 68.687 26.894 126.775 1.00 11.26 ? 397 ILE N O 1 ATOM 2464 C CB . ILE A 1 316 ? 66.186 27.065 129.262 1.00 6.77 ? 397 ILE N CB 1 ATOM 2465 C CG1 . ILE A 1 316 ? 65.929 27.861 130.560 1.00 6.86 ? 397 ILE N CG1 1 ATOM 2466 C CG2 . ILE A 1 316 ? 66.731 25.682 129.600 1.00 8.84 ? 397 ILE N CG2 1 ATOM 2467 C CD1 . ILE A 1 316 ? 67.042 27.859 131.643 1.00 4.16 ? 397 ILE N CD1 1 ATOM 2468 N N . VAL A 1 317 ? 66.627 26.855 126.147 1.00 8.01 ? 398 VAL N N 1 ATOM 2469 C CA . VAL A 1 317 ? 66.904 26.244 124.845 1.00 4.60 ? 398 VAL N CA 1 ATOM 2470 C C . VAL A 1 317 ? 66.243 27.307 123.965 1.00 6.53 ? 398 VAL N C 1 ATOM 2471 O O . VAL A 1 317 ? 65.197 27.905 124.293 1.00 8.76 ? 398 VAL N O 1 ATOM 2472 C CB . VAL A 1 317 ? 66.160 24.943 124.607 1.00 2.57 ? 398 VAL N CB 1 ATOM 2473 C CG1 . VAL A 1 317 ? 66.443 24.498 123.240 1.00 2.00 ? 398 VAL N CG1 1 ATOM 2474 C CG2 . VAL A 1 317 ? 66.590 23.856 125.557 1.00 3.44 ? 398 VAL N CG2 1 ATOM 2475 N N . LEU A 1 318 ? 66.920 27.498 122.843 1.00 7.76 ? 399 LEU N N 1 ATOM 2476 C CA . LEU A 1 318 ? 66.653 28.557 121.888 1.00 6.77 ? 399 LEU N CA 1 ATOM 2477 C C . LEU A 1 318 ? 65.477 28.101 121.064 1.00 6.09 ? 399 LEU N C 1 ATOM 2478 O O . LEU A 1 318 ? 65.289 26.888 120.962 1.00 12.58 ? 399 LEU N O 1 ATOM 2479 C CB . LEU A 1 318 ? 67.983 28.707 121.132 1.00 5.10 ? 399 LEU N CB 1 ATOM 2480 C CG . LEU A 1 318 ? 68.557 30.065 120.851 1.00 2.84 ? 399 LEU N CG 1 ATOM 2481 C CD1 . LEU A 1 318 ? 67.981 30.580 119.562 1.00 3.53 ? 399 LEU N CD1 1 ATOM 2482 C CD2 . LEU A 1 318 ? 68.273 30.972 122.015 1.00 2.31 ? 399 LEU N CD2 1 ATOM 2483 N N . ASN A 1 319 ? 64.651 28.982 120.503 1.00 8.12 ? 400 ASN N N 1 ATOM 2484 C CA . ASN A 1 319 ? 63.463 28.517 119.770 1.00 5.49 ? 400 ASN N CA 1 ATOM 2485 C C . ASN A 1 319 ? 63.844 27.883 118.450 1.00 4.48 ? 400 ASN N C 1 ATOM 2486 O O . ASN A 1 319 ? 63.077 27.042 117.961 1.00 6.93 ? 400 ASN N O 1 ATOM 2487 C CB . ASN A 1 319 ? 62.488 29.643 119.483 1.00 3.68 ? 400 ASN N CB 1 ATOM 2488 C CG . ASN A 1 319 ? 61.222 29.180 118.785 1.00 4.83 ? 400 ASN N CG 1 ATOM 2489 O OD1 . ASN A 1 319 ? 60.656 28.110 119.045 1.00 5.16 ? 400 ASN N OD1 1 ATOM 2490 N ND2 . ASN A 1 319 ? 60.813 30.027 117.854 1.00 3.27 ? 400 ASN N ND2 1 ATOM 2491 N N . THR A 1 320 ? 65.025 28.213 117.893 1.00 2.87 ? 401 THR N N 1 ATOM 2492 C CA . THR A 1 320 ? 65.579 27.473 116.779 1.00 5.07 ? 401 THR N CA 1 ATOM 2493 C C . THR A 1 320 ? 66.274 26.200 117.229 1.00 4.62 ? 401 THR N C 1 ATOM 2494 O O . THR A 1 320 ? 67.096 25.684 116.476 1.00 8.24 ? 401 THR N O 1 ATOM 2495 C CB . THR A 1 320 ? 66.633 28.237 115.941 1.00 4.15 ? 401 THR N CB 1 ATOM 2496 O OG1 . THR A 1 320 ? 67.555 28.852 116.813 1.00 3.41 ? 401 THR N OG1 1 ATOM 2497 C CG2 . THR A 1 320 ? 65.988 29.229 115.028 1.00 2.16 ? 401 THR N CG2 1 ATOM 2498 N N . ASP A 1 321 ? 65.944 25.649 118.400 1.00 5.10 ? 402 ASP N N 1 ATOM 2499 C CA . ASP A 1 321 ? 66.479 24.380 118.850 1.00 5.35 ? 402 ASP N CA 1 ATOM 2500 C C . ASP A 1 321 ? 65.383 23.500 119.443 1.00 4.72 ? 402 ASP N C 1 ATOM 2501 O O . ASP A 1 321 ? 64.357 23.993 119.946 1.00 2.15 ? 402 ASP N O 1 ATOM 2502 C CB . ASP A 1 321 ? 67.545 24.599 119.899 1.00 5.78 ? 402 ASP N CB 1 ATOM 2503 C CG . ASP A 1 321 ? 68.967 24.601 119.374 1.00 8.93 ? 402 ASP N CG 1 ATOM 2504 O OD1 . ASP A 1 321 ? 69.329 23.635 118.671 1.00 10.88 ? 402 ASP N OD1 1 ATOM 2505 O OD2 . ASP A 1 321 ? 69.684 25.567 119.703 1.00 10.91 ? 402 ASP N OD2 1 ATOM 2506 N N . TRP A 1 322 ? 65.582 22.187 119.460 1.00 4.18 ? 403 TRP N N 1 ATOM 2507 C CA . TRP A 1 322 ? 64.506 21.335 119.901 1.00 3.36 ? 403 TRP N CA 1 ATOM 2508 C C . TRP A 1 322 ? 64.545 21.192 121.420 1.00 3.49 ? 403 TRP N C 1 ATOM 2509 O O . TRP A 1 322 ? 65.595 21.298 122.060 1.00 4.37 ? 403 TRP N O 1 ATOM 2510 C CB . TRP A 1 322 ? 64.664 19.983 119.200 1.00 2.82 ? 403 TRP N CB 1 ATOM 2511 C CG . TRP A 1 322 ? 64.504 19.923 117.673 1.00 2.01 ? 403 TRP N CG 1 ATOM 2512 C CD1 . TRP A 1 322 ? 65.511 19.516 116.842 1.00 2.00 ? 403 TRP N CD1 1 ATOM 2513 C CD2 . TRP A 1 322 ? 63.365 20.192 116.989 1.00 3.41 ? 403 TRP N CD2 1 ATOM 2514 N NE1 . TRP A 1 322 ? 65.022 19.517 115.650 1.00 2.00 ? 403 TRP N NE1 1 ATOM 2515 C CE2 . TRP A 1 322 ? 63.745 19.907 115.699 1.00 3.52 ? 403 TRP N CE2 1 ATOM 2516 C CE3 . TRP A 1 322 ? 62.067 20.616 117.258 1.00 3.41 ? 403 TRP N CE3 1 ATOM 2517 C CZ2 . TRP A 1 322 ? 62.812 20.055 114.680 1.00 2.21 ? 403 TRP N CZ2 1 ATOM 2518 C CZ3 . TRP A 1 322 ? 61.124 20.764 116.237 1.00 3.00 ? 403 TRP N CZ3 1 ATOM 2519 C CH2 . TRP A 1 322 ? 61.513 20.484 114.946 1.00 2.00 ? 403 TRP N CH2 1 ATOM 2520 N N . SER A 1 323 ? 63.360 21.012 121.990 1.00 2.00 ? 404 SER N N 1 ATOM 2521 C CA . SER A 1 323 ? 63.221 20.650 123.386 1.00 4.39 ? 404 SER N CA 1 ATOM 2522 C C . SER A 1 323 ? 62.384 19.350 123.442 1.00 5.14 ? 404 SER N C 1 ATOM 2523 O O . SER A 1 323 ? 62.523 18.498 122.522 1.00 6.29 ? 404 SER N O 1 ATOM 2524 C CB . SER A 1 323 ? 62.566 21.803 124.128 1.00 2.50 ? 404 SER N CB 1 ATOM 2525 O OG . SER A 1 323 ? 61.450 22.254 123.408 1.00 5.02 ? 404 SER N OG 1 ATOM 2526 N N . GLY A 1 324 ? 61.525 19.169 124.467 1.00 2.66 ? 405 GLY N N 1 ATOM 2527 C CA . GLY A 1 324 ? 60.740 17.986 124.677 1.00 2.70 ? 405 GLY N CA 1 ATOM 2528 C C . GLY A 1 324 ? 60.160 18.100 126.064 1.00 4.49 ? 405 GLY N C 1 ATOM 2529 O O . GLY A 1 324 ? 59.684 19.170 126.473 1.00 5.60 ? 405 GLY N O 1 ATOM 2530 N N . TYR A 1 325 ? 60.276 17.000 126.804 1.00 5.75 ? 406 TYR N N 1 ATOM 2531 C CA . TYR A 1 325 ? 59.660 16.808 128.112 1.00 4.54 ? 406 TYR N CA 1 ATOM 2532 C C . TYR A 1 325 ? 60.346 17.568 129.231 1.00 7.05 ? 406 TYR N C 1 ATOM 2533 O O . TYR A 1 325 ? 61.574 17.648 129.146 1.00 7.03 ? 406 TYR N O 1 ATOM 2534 C CB . TYR A 1 325 ? 59.683 15.311 128.369 1.00 4.04 ? 406 TYR N CB 1 ATOM 2535 C CG . TYR A 1 325 ? 58.485 14.497 127.895 1.00 6.48 ? 406 TYR N CG 1 ATOM 2536 C CD1 . TYR A 1 325 ? 57.606 15.035 126.987 1.00 6.18 ? 406 TYR N CD1 1 ATOM 2537 C CD2 . TYR A 1 325 ? 58.170 13.295 128.487 1.00 6.34 ? 406 TYR N CD2 1 ATOM 2538 C CE1 . TYR A 1 325 ? 56.415 14.383 126.697 1.00 6.77 ? 406 TYR N CE1 1 ATOM 2539 C CE2 . TYR A 1 325 ? 56.992 12.653 128.195 1.00 5.64 ? 406 TYR N CE2 1 ATOM 2540 C CZ . TYR A 1 325 ? 56.107 13.192 127.306 1.00 5.16 ? 406 TYR N CZ 1 ATOM 2541 O OH . TYR A 1 325 ? 54.888 12.620 127.033 1.00 4.47 ? 406 TYR N OH 1 ATOM 2542 N N . SER A 1 326 ? 59.712 18.206 130.213 1.00 6.47 ? 407 SER N N 1 ATOM 2543 C CA . SER A 1 326 ? 60.517 18.673 131.335 1.00 10.19 ? 407 SER N CA 1 ATOM 2544 C C . SER A 1 326 ? 59.995 18.112 132.646 1.00 7.26 ? 407 SER N C 1 ATOM 2545 O O . SER A 1 326 ? 58.883 17.600 132.656 1.00 2.08 ? 407 SER N O 1 ATOM 2546 C CB . SER A 1 326 ? 60.534 20.183 131.347 1.00 10.64 ? 407 SER N CB 1 ATOM 2547 O OG . SER A 1 326 ? 59.250 20.777 131.450 1.00 10.36 ? 407 SER N OG 1 ATOM 2548 N N . GLY A 1 327 ? 60.718 18.121 133.758 1.00 7.88 ? 408 GLY N N 1 ATOM 2549 C CA . GLY A 1 327 ? 60.248 17.617 135.036 1.00 7.51 ? 408 GLY N CA 1 ATOM 2550 C C . GLY A 1 327 ? 61.136 18.202 136.113 1.00 7.64 ? 408 GLY N C 1 ATOM 2551 O O . GLY A 1 327 ? 62.283 18.592 135.847 1.00 10.03 ? 408 GLY N O 1 ATOM 2552 N N . SER A 1 328 ? 60.611 18.321 137.323 1.00 7.00 ? 409 SER N N 1 ATOM 2553 C CA . SER A 1 328 ? 61.322 18.833 138.495 1.00 6.35 ? 409 SER N CA 1 ATOM 2554 C C . SER A 1 328 ? 62.116 17.746 139.209 1.00 7.15 ? 409 SER N C 1 ATOM 2555 O O . SER A 1 328 ? 61.727 16.550 139.197 1.00 4.35 ? 409 SER N O 1 ATOM 2556 C CB . SER A 1 328 ? 60.350 19.369 139.486 1.00 4.49 ? 409 SER N CB 1 ATOM 2557 O OG . SER A 1 328 ? 59.397 18.311 139.713 1.00 4.79 ? 409 SER N OG 1 ATOM 2558 N N . PHE A 1 329 ? 63.186 18.199 139.878 1.00 6.74 ? 410 PHE N N 1 ATOM 2559 C CA . PHE A 1 329 ? 63.898 17.346 140.828 1.00 6.78 ? 410 PHE N CA 1 ATOM 2560 C C . PHE A 1 329 ? 64.689 18.256 141.774 1.00 6.34 ? 410 PHE N C 1 ATOM 2561 O O . PHE A 1 329 ? 64.964 19.403 141.429 1.00 6.80 ? 410 PHE N O 1 ATOM 2562 C CB . PHE A 1 329 ? 64.836 16.373 140.083 1.00 4.62 ? 410 PHE N CB 1 ATOM 2563 C CG . PHE A 1 329 ? 66.162 16.963 139.641 1.00 3.20 ? 410 PHE N CG 1 ATOM 2564 C CD1 . PHE A 1 329 ? 67.262 16.929 140.507 1.00 2.08 ? 410 PHE N CD1 1 ATOM 2565 C CD2 . PHE A 1 329 ? 66.278 17.502 138.369 1.00 3.59 ? 410 PHE N CD2 1 ATOM 2566 C CE1 . PHE A 1 329 ? 68.471 17.436 140.078 1.00 2.50 ? 410 PHE N CE1 1 ATOM 2567 C CE2 . PHE A 1 329 ? 67.509 18.002 137.964 1.00 3.34 ? 410 PHE N CE2 1 ATOM 2568 C CZ . PHE A 1 329 ? 68.592 17.965 138.813 1.00 2.57 ? 410 PHE N CZ 1 ATOM 2569 N N . MET A 1 330 ? 65.014 17.831 142.983 1.00 6.10 ? 411 MET N N 1 ATOM 2570 C CA . MET A 1 330 ? 65.910 18.561 143.899 1.00 3.24 ? 411 MET N CA 1 ATOM 2571 C C . MET A 1 330 ? 66.847 17.575 144.614 1.00 2.71 ? 411 MET N C 1 ATOM 2572 O O . MET A 1 330 ? 66.548 16.362 144.737 1.00 2.00 ? 411 MET N O 1 ATOM 2573 C CB . MET A 1 330 ? 65.138 19.310 144.970 1.00 3.38 ? 411 MET N CB 1 ATOM 2574 C CG . MET A 1 330 ? 64.216 20.340 144.384 1.00 4.47 ? 411 MET N CG 1 ATOM 2575 S SD . MET A 1 330 ? 63.519 21.409 145.645 1.00 8.48 ? 411 MET N SD 1 ATOM 2576 C CE . MET A 1 330 ? 62.274 20.229 146.077 1.00 4.99 ? 411 MET N CE 1 ATOM 2577 N N . ASP A 1 331 ? 67.999 18.050 145.109 1.00 2.95 ? 412 ASP N N 1 ATOM 2578 C CA . ASP A 1 331 ? 68.893 17.168 145.837 1.00 2.00 ? 412 ASP N CA 1 ATOM 2579 C C . ASP A 1 331 ? 68.504 17.453 147.247 1.00 3.06 ? 412 ASP N C 1 ATOM 2580 O O . ASP A 1 331 ? 68.983 18.411 147.884 1.00 4.01 ? 412 ASP N O 1 ATOM 2581 C CB . ASP A 1 331 ? 70.338 17.523 145.683 1.00 4.19 ? 412 ASP N CB 1 ATOM 2582 C CG . ASP A 1 331 ? 71.408 16.655 146.405 1.00 9.74 ? 412 ASP N CG 1 ATOM 2583 O OD1 . ASP A 1 331 ? 71.124 15.713 147.180 1.00 10.36 ? 412 ASP N OD1 1 ATOM 2584 O OD2 . ASP A 1 331 ? 72.584 16.948 146.127 1.00 10.71 ? 412 ASP N OD2 1 ATOM 2585 N N . TYR A 1 332 A 67.658 16.539 147.752 1.00 3.56 ? 412 TYR N N 1 ATOM 2586 C CA . TYR A 1 332 A 67.100 16.695 149.093 1.00 3.78 ? 412 TYR N CA 1 ATOM 2587 C C . TYR A 1 332 A 68.121 16.516 150.215 1.00 3.72 ? 412 TYR N C 1 ATOM 2588 O O . TYR A 1 332 A 67.881 16.883 151.370 1.00 5.85 ? 412 TYR N O 1 ATOM 2589 C CB . TYR A 1 332 A 65.957 15.712 149.295 1.00 4.55 ? 412 TYR N CB 1 ATOM 2590 C CG . TYR A 1 332 A 64.800 16.083 148.398 1.00 5.27 ? 412 TYR N CG 1 ATOM 2591 C CD1 . TYR A 1 332 A 63.870 17.033 148.813 1.00 6.63 ? 412 TYR N CD1 1 ATOM 2592 C CD2 . TYR A 1 332 A 64.686 15.477 147.159 1.00 6.41 ? 412 TYR N CD2 1 ATOM 2593 C CE1 . TYR A 1 332 A 62.824 17.379 147.971 1.00 7.73 ? 412 TYR N CE1 1 ATOM 2594 C CE2 . TYR A 1 332 A 63.648 15.814 146.313 1.00 6.16 ? 412 TYR N CE2 1 ATOM 2595 C CZ . TYR A 1 332 A 62.732 16.761 146.729 1.00 7.84 ? 412 TYR N CZ 1 ATOM 2596 O OH . TYR A 1 332 A 61.712 17.137 145.879 1.00 11.13 ? 412 TYR N OH 1 ATOM 2597 N N . TRP A 1 333 B 69.300 16.009 149.885 1.00 2.92 ? 412 TRP N N 1 ATOM 2598 C CA . TRP A 1 333 B 70.312 15.742 150.882 1.00 5.42 ? 412 TRP N CA 1 ATOM 2599 C C . TRP A 1 333 B 71.488 16.694 150.791 1.00 7.47 ? 412 TRP N C 1 ATOM 2600 O O . TRP A 1 333 B 72.548 16.499 151.400 1.00 8.57 ? 412 TRP N O 1 ATOM 2601 C CB . TRP A 1 333 B 70.712 14.289 150.679 1.00 4.21 ? 412 TRP N CB 1 ATOM 2602 C CG . TRP A 1 333 B 69.553 13.325 150.917 1.00 3.67 ? 412 TRP N CG 1 ATOM 2603 C CD1 . TRP A 1 333 B 69.381 12.782 152.162 1.00 3.18 ? 412 TRP N CD1 1 ATOM 2604 C CD2 . TRP A 1 333 B 68.615 12.863 150.028 1.00 3.01 ? 412 TRP N CD2 1 ATOM 2605 N NE1 . TRP A 1 333 B 68.361 11.972 152.082 1.00 2.81 ? 412 TRP N NE1 1 ATOM 2606 C CE2 . TRP A 1 333 B 67.881 11.996 150.825 1.00 2.26 ? 412 TRP N CE2 1 ATOM 2607 C CE3 . TRP A 1 333 B 68.284 13.023 148.722 1.00 2.00 ? 412 TRP N CE3 1 ATOM 2608 C CZ2 . TRP A 1 333 B 66.811 11.257 150.367 1.00 2.00 ? 412 TRP N CZ2 1 ATOM 2609 C CZ3 . TRP A 1 333 B 67.220 12.282 148.278 1.00 2.44 ? 412 TRP N CZ3 1 ATOM 2610 C CH2 . TRP A 1 333 B 66.482 11.405 149.063 1.00 2.00 ? 412 TRP N CH2 1 ATOM 2611 N N . ALA A 1 334 ? 71.310 17.774 150.023 1.00 9.94 ? 413 ALA N N 1 ATOM 2612 C CA . ALA A 1 334 ? 72.433 18.665 149.789 1.00 10.84 ? 413 ALA N CA 1 ATOM 2613 C C . ALA A 1 334 ? 72.530 19.569 150.976 1.00 12.53 ? 413 ALA N C 1 ATOM 2614 O O . ALA A 1 334 ? 71.500 19.811 151.584 1.00 16.72 ? 413 ALA N O 1 ATOM 2615 C CB . ALA A 1 334 ? 72.183 19.477 148.591 1.00 10.58 ? 413 ALA N CB 1 ATOM 2616 N N . GLU A 1 335 ? 73.652 20.177 151.334 1.00 16.60 ? 414 GLU N N 1 ATOM 2617 C CA . GLU A 1 335 ? 73.732 20.914 152.606 1.00 17.92 ? 414 GLU N CA 1 ATOM 2618 C C . GLU A 1 335 ? 73.176 22.331 152.555 1.00 17.02 ? 414 GLU N C 1 ATOM 2619 O O . GLU A 1 335 ? 73.354 23.040 151.551 1.00 16.51 ? 414 GLU N O 1 ATOM 2620 C CB . GLU A 1 335 ? 75.182 20.988 153.086 1.00 17.74 ? 414 GLU N CB 1 ATOM 2621 C CG . GLU A 1 335 ? 75.737 19.630 153.514 1.00 19.02 ? 414 GLU N CG 1 ATOM 2622 C CD . GLU A 1 335 ? 77.108 19.682 154.175 1.00 19.71 ? 414 GLU N CD 1 ATOM 2623 O OE1 . GLU A 1 335 ? 77.186 19.995 155.363 1.00 20.12 ? 414 GLU N OE1 1 ATOM 2624 O OE2 . GLU A 1 335 ? 78.098 19.387 153.508 1.00 20.23 ? 414 GLU N OE2 1 ATOM 2625 N N . GLY A 1 336 ? 72.433 22.731 153.592 1.00 16.04 ? 415 GLY N N 1 ATOM 2626 C CA . GLY A 1 336 ? 72.013 24.120 153.632 1.00 16.66 ? 415 GLY N CA 1 ATOM 2627 C C . GLY A 1 336 ? 70.672 24.478 154.239 1.00 14.58 ? 415 GLY N C 1 ATOM 2628 O O . GLY A 1 336 ? 69.907 23.651 154.718 1.00 15.28 ? 415 GLY N O 1 ATOM 2629 N N . GLU A 1 337 ? 70.413 25.779 154.156 1.00 14.21 ? 416 GLU N N 1 ATOM 2630 C CA . GLU A 1 337 ? 69.208 26.385 154.694 1.00 14.96 ? 416 GLU N CA 1 ATOM 2631 C C . GLU A 1 337 ? 67.975 25.877 153.946 1.00 14.05 ? 416 GLU N C 1 ATOM 2632 O O . GLU A 1 337 ? 66.931 25.646 154.555 1.00 14.38 ? 416 GLU N O 1 ATOM 2633 C CB . GLU A 1 337 ? 69.305 27.904 154.572 1.00 15.80 ? 416 GLU N CB 1 ATOM 2634 C CG . GLU A 1 337 ? 70.599 28.531 155.111 1.00 17.84 ? 416 GLU N CG 1 ATOM 2635 C CD . GLU A 1 337 ? 70.899 28.264 156.578 1.00 18.94 ? 416 GLU N CD 1 ATOM 2636 O OE1 . GLU A 1 337 ? 70.293 28.912 157.432 1.00 19.39 ? 416 GLU N OE1 1 ATOM 2637 O OE2 . GLU A 1 337 ? 71.743 27.412 156.860 1.00 19.74 ? 416 GLU N OE2 1 ATOM 2638 N N . CYS A 1 338 ? 68.073 25.584 152.650 1.00 12.60 ? 417 CYS N N 1 ATOM 2639 C CA . CYS A 1 338 ? 66.920 25.283 151.829 1.00 9.51 ? 417 CYS N CA 1 ATOM 2640 C C . CYS A 1 338 ? 67.198 24.375 150.639 1.00 9.44 ? 417 CYS N C 1 ATOM 2641 O O . CYS A 1 338 ? 68.308 23.881 150.380 1.00 9.95 ? 417 CYS N O 1 ATOM 2642 C CB . CYS A 1 338 ? 66.329 26.609 151.320 1.00 8.00 ? 417 CYS N CB 1 ATOM 2643 S SG . CYS A 1 338 ? 67.658 27.538 150.534 1.00 6.76 ? 417 CYS N SG 1 ATOM 2644 N N . TYR A 1 339 ? 66.090 24.161 149.935 1.00 8.66 ? 418 TYR N N 1 ATOM 2645 C CA . TYR A 1 339 ? 66.030 23.336 148.769 1.00 9.67 ? 418 TYR N CA 1 ATOM 2646 C C . TYR A 1 339 ? 66.404 24.124 147.564 1.00 10.43 ? 418 TYR N C 1 ATOM 2647 O O . TYR A 1 339 ? 65.780 25.143 147.256 1.00 12.28 ? 418 TYR N O 1 ATOM 2648 C CB . TYR A 1 339 ? 64.614 22.777 148.608 1.00 6.68 ? 418 TYR N CB 1 ATOM 2649 C CG . TYR A 1 339 ? 64.386 21.749 149.683 1.00 4.31 ? 418 TYR N CG 1 ATOM 2650 C CD1 . TYR A 1 339 ? 65.375 20.834 149.941 1.00 4.93 ? 418 TYR N CD1 1 ATOM 2651 C CD2 . TYR A 1 339 ? 63.223 21.738 150.394 1.00 5.52 ? 418 TYR N CD2 1 ATOM 2652 C CE1 . TYR A 1 339 ? 65.256 19.888 150.920 1.00 5.62 ? 418 TYR N CE1 1 ATOM 2653 C CE2 . TYR A 1 339 ? 63.068 20.784 151.392 1.00 7.04 ? 418 TYR N CE2 1 ATOM 2654 C CZ . TYR A 1 339 ? 64.086 19.868 151.632 1.00 6.59 ? 418 TYR N CZ 1 ATOM 2655 O OH . TYR A 1 339 ? 63.945 18.896 152.598 1.00 6.78 ? 418 TYR N OH 1 ATOM 2656 N N . ARG A 1 340 ? 67.440 23.627 146.914 1.00 10.55 ? 419 ARG N N 1 ATOM 2657 C CA . ARG A 1 340 ? 67.833 24.179 145.655 1.00 9.76 ? 419 ARG N CA 1 ATOM 2658 C C . ARG A 1 340 ? 66.936 23.505 144.616 1.00 10.04 ? 419 ARG N C 1 ATOM 2659 O O . ARG A 1 340 ? 66.906 22.260 144.497 1.00 9.63 ? 419 ARG N O 1 ATOM 2660 C CB . ARG A 1 340 ? 69.258 23.850 145.449 1.00 10.14 ? 419 ARG N CB 1 ATOM 2661 C CG . ARG A 1 340 ? 69.816 24.708 144.361 1.00 9.61 ? 419 ARG N CG 1 ATOM 2662 C CD . ARG A 1 340 ? 71.165 25.059 144.859 1.00 8.60 ? 419 ARG N CD 1 ATOM 2663 N NE . ARG A 1 340 ? 71.913 25.634 143.788 1.00 7.78 ? 419 ARG N NE 1 ATOM 2664 C CZ . ARG A 1 340 ? 73.099 26.148 144.060 1.00 9.20 ? 419 ARG N CZ 1 ATOM 2665 N NH1 . ARG A 1 340 ? 73.557 26.198 145.302 1.00 10.42 ? 419 ARG N NH1 1 ATOM 2666 N NH2 . ARG A 1 340 ? 73.858 26.630 143.086 1.00 9.33 ? 419 ARG N NH2 1 ATOM 2667 N N . ALA A 1 341 ? 66.160 24.353 143.936 1.00 11.24 ? 420 ALA N N 1 ATOM 2668 C CA . ALA A 1 341 ? 65.213 23.855 142.959 1.00 10.19 ? 420 ALA N CA 1 ATOM 2669 C C . ALA A 1 341 ? 65.986 23.635 141.653 1.00 8.48 ? 420 ALA N C 1 ATOM 2670 O O . ALA A 1 341 ? 66.990 24.296 141.367 1.00 8.95 ? 420 ALA N O 1 ATOM 2671 C CB . ALA A 1 341 ? 64.095 24.880 142.795 1.00 7.78 ? 420 ALA N CB 1 ATOM 2672 N N . CYS A 1 342 ? 65.537 22.618 140.919 1.00 5.71 ? 421 CYS N N 1 ATOM 2673 C CA . CYS A 1 342 ? 66.195 22.197 139.725 1.00 5.81 ? 421 CYS N CA 1 ATOM 2674 C C . CYS A 1 342 ? 65.124 21.534 138.865 1.00 4.02 ? 421 CYS N C 1 ATOM 2675 O O . CYS A 1 342 ? 64.037 21.114 139.302 1.00 2.00 ? 421 CYS N O 1 ATOM 2676 C CB . CYS A 1 342 ? 67.310 21.155 140.025 1.00 3.81 ? 421 CYS N CB 1 ATOM 2677 S SG . CYS A 1 342 ? 68.444 21.376 141.393 1.00 4.00 ? 421 CYS N SG 1 ATOM 2678 N N . PHE A 1 343 ? 65.496 21.387 137.608 1.00 2.00 ? 422 PHE N N 1 ATOM 2679 C CA . PHE A 1 343 ? 64.656 20.738 136.652 1.00 2.35 ? 422 PHE N CA 1 ATOM 2680 C C . PHE A 1 343 ? 65.577 20.149 135.563 1.00 3.68 ? 422 PHE N C 1 ATOM 2681 O O . PHE A 1 343 ? 66.811 20.373 135.557 1.00 5.75 ? 422 PHE N O 1 ATOM 2682 C CB . PHE A 1 343 ? 63.665 21.797 136.086 1.00 2.90 ? 422 PHE N CB 1 ATOM 2683 C CG . PHE A 1 343 ? 64.282 22.932 135.232 1.00 2.10 ? 422 PHE N CG 1 ATOM 2684 C CD1 . PHE A 1 343 ? 64.546 22.718 133.875 1.00 2.35 ? 422 PHE N CD1 1 ATOM 2685 C CD2 . PHE A 1 343 ? 64.575 24.152 135.815 1.00 2.02 ? 422 PHE N CD2 1 ATOM 2686 C CE1 . PHE A 1 343 ? 65.089 23.693 133.089 1.00 2.00 ? 422 PHE N CE1 1 ATOM 2687 C CE2 . PHE A 1 343 ? 65.124 25.120 135.013 1.00 2.91 ? 422 PHE N CE2 1 ATOM 2688 C CZ . PHE A 1 343 ? 65.382 24.891 133.669 1.00 2.00 ? 422 PHE N CZ 1 ATOM 2689 N N . TYR A 1 344 ? 64.931 19.503 134.578 1.00 2.21 ? 423 TYR N N 1 ATOM 2690 C CA . TYR A 1 344 ? 65.602 18.942 133.426 1.00 2.80 ? 423 TYR N CA 1 ATOM 2691 C C . TYR A 1 344 ? 64.819 19.221 132.138 1.00 7.47 ? 423 TYR N C 1 ATOM 2692 O O . TYR A 1 344 ? 63.594 19.443 132.218 1.00 8.15 ? 423 TYR N O 1 ATOM 2693 C CB . TYR A 1 344 ? 65.728 17.459 133.634 1.00 5.07 ? 423 TYR N CB 1 ATOM 2694 C CG . TYR A 1 344 ? 64.479 16.609 133.462 1.00 4.10 ? 423 TYR N CG 1 ATOM 2695 C CD1 . TYR A 1 344 ? 64.101 16.260 132.199 1.00 3.67 ? 423 TYR N CD1 1 ATOM 2696 C CD2 . TYR A 1 344 ? 63.801 16.110 134.542 1.00 4.78 ? 423 TYR N CD2 1 ATOM 2697 C CE1 . TYR A 1 344 ? 63.060 15.412 132.004 1.00 2.86 ? 423 TYR N CE1 1 ATOM 2698 C CE2 . TYR A 1 344 ? 62.748 15.244 134.359 1.00 5.12 ? 423 TYR N CE2 1 ATOM 2699 C CZ . TYR A 1 344 ? 62.391 14.906 133.082 1.00 4.14 ? 423 TYR N CZ 1 ATOM 2700 O OH . TYR A 1 344 ? 61.356 14.039 132.832 1.00 4.46 ? 423 TYR N OH 1 ATOM 2701 N N . VAL A 1 345 ? 65.383 19.128 130.927 1.00 4.63 ? 424 VAL N N 1 ATOM 2702 C CA . VAL A 1 345 ? 64.649 19.345 129.689 1.00 2.26 ? 424 VAL N CA 1 ATOM 2703 C C . VAL A 1 345 ? 65.177 18.233 128.771 1.00 4.03 ? 424 VAL N C 1 ATOM 2704 O O . VAL A 1 345 ? 66.381 18.160 128.445 1.00 5.60 ? 424 VAL N O 1 ATOM 2705 C CB . VAL A 1 345 ? 64.978 20.713 129.016 1.00 2.71 ? 424 VAL N CB 1 ATOM 2706 C CG1 . VAL A 1 345 ? 63.972 21.018 127.952 1.00 2.00 ? 424 VAL N CG1 1 ATOM 2707 C CG2 . VAL A 1 345 ? 65.009 21.798 130.031 1.00 2.00 ? 424 VAL N CG2 1 ATOM 2708 N N . GLU A 1 346 ? 64.302 17.308 128.398 1.00 5.77 ? 425 GLU N N 1 ATOM 2709 C CA . GLU A 1 346 ? 64.575 16.268 127.415 1.00 2.88 ? 425 GLU N CA 1 ATOM 2710 C C . GLU A 1 346 ? 64.818 16.962 126.080 1.00 3.27 ? 425 GLU N C 1 ATOM 2711 O O . GLU A 1 346 ? 64.065 17.883 125.740 1.00 2.58 ? 425 GLU N O 1 ATOM 2712 C CB . GLU A 1 346 ? 63.370 15.353 127.285 1.00 4.06 ? 425 GLU N CB 1 ATOM 2713 C CG . GLU A 1 346 ? 63.334 14.539 125.974 1.00 8.65 ? 425 GLU N CG 1 ATOM 2714 C CD . GLU A 1 346 ? 62.055 13.737 125.823 1.00 10.61 ? 425 GLU N CD 1 ATOM 2715 O OE1 . GLU A 1 346 ? 61.003 14.279 125.481 1.00 11.12 ? 425 GLU N OE1 1 ATOM 2716 O OE2 . GLU A 1 346 ? 62.114 12.547 126.066 1.00 15.32 ? 425 GLU N OE2 1 ATOM 2717 N N . LEU A 1 347 ? 65.778 16.524 125.276 1.00 2.54 ? 426 LEU N N 1 ATOM 2718 C CA . LEU A 1 347 ? 66.008 17.161 123.994 1.00 2.45 ? 426 LEU N CA 1 ATOM 2719 C C . LEU A 1 347 ? 65.790 16.094 122.931 1.00 2.66 ? 426 LEU N C 1 ATOM 2720 O O . LEU A 1 347 ? 66.681 15.282 122.675 1.00 2.08 ? 426 LEU N O 1 ATOM 2721 C CB . LEU A 1 347 ? 67.425 17.713 123.976 1.00 2.00 ? 426 LEU N CB 1 ATOM 2722 C CG . LEU A 1 347 ? 67.870 18.739 125.000 1.00 2.00 ? 426 LEU N CG 1 ATOM 2723 C CD1 . LEU A 1 347 ? 69.260 19.053 124.583 1.00 2.03 ? 426 LEU N CD1 1 ATOM 2724 C CD2 . LEU A 1 347 ? 67.033 20.026 125.072 1.00 2.00 ? 426 LEU N CD2 1 ATOM 2725 N N . ILE A 1 348 ? 64.592 16.044 122.335 1.00 2.00 ? 427 ILE N N 1 ATOM 2726 C CA . ILE A 1 348 ? 64.229 15.001 121.380 1.00 3.24 ? 427 ILE N CA 1 ATOM 2727 C C . ILE A 1 348 ? 64.765 15.229 119.983 1.00 2.79 ? 427 ILE N C 1 ATOM 2728 O O . ILE A 1 348 ? 64.369 16.147 119.264 1.00 2.70 ? 427 ILE N O 1 ATOM 2729 C CB . ILE A 1 348 ? 62.730 14.834 121.237 1.00 2.43 ? 427 ILE N CB 1 ATOM 2730 C CG1 . ILE A 1 348 ? 62.017 14.979 122.526 1.00 2.32 ? 427 ILE N CG1 1 ATOM 2731 C CG2 . ILE A 1 348 ? 62.483 13.419 120.723 1.00 2.00 ? 427 ILE N CG2 1 ATOM 2732 C CD1 . ILE A 1 348 ? 60.492 14.822 122.440 1.00 2.00 ? 427 ILE N CD1 1 ATOM 2733 N N . ARG A 1 349 ? 65.610 14.331 119.524 1.00 4.47 ? 428 ARG N N 1 ATOM 2734 C CA . ARG A 1 349 ? 66.284 14.441 118.235 1.00 8.06 ? 428 ARG N CA 1 ATOM 2735 C C . ARG A 1 349 ? 65.819 13.265 117.415 1.00 5.43 ? 428 ARG N C 1 ATOM 2736 O O . ARG A 1 349 ? 65.800 12.162 117.955 1.00 8.39 ? 428 ARG N O 1 ATOM 2737 C CB . ARG A 1 349 ? 67.759 14.402 118.493 1.00 8.57 ? 428 ARG N CB 1 ATOM 2738 C CG . ARG A 1 349 ? 68.018 15.691 119.162 1.00 9.46 ? 428 ARG N CG 1 ATOM 2739 C CD . ARG A 1 349 ? 68.981 16.438 118.320 1.00 9.84 ? 428 ARG N CD 1 ATOM 2740 N NE . ARG A 1 349 ? 68.632 16.786 116.974 1.00 11.74 ? 428 ARG N NE 1 ATOM 2741 C CZ . ARG A 1 349 ? 69.437 17.618 116.332 1.00 13.70 ? 428 ARG N CZ 1 ATOM 2742 N NH1 . ARG A 1 349 ? 70.499 18.104 116.916 1.00 16.50 ? 428 ARG N NH1 1 ATOM 2743 N NH2 . ARG A 1 349 ? 69.225 18.019 115.101 1.00 13.20 ? 428 ARG N NH2 1 ATOM 2744 N N . GLY A 1 350 ? 65.467 13.348 116.157 1.00 5.17 ? 429 GLY N N 1 ATOM 2745 C CA . GLY A 1 350 ? 64.958 12.152 115.528 1.00 8.72 ? 429 GLY N CA 1 ATOM 2746 C C . GLY A 1 350 ? 63.591 12.294 114.912 1.00 10.06 ? 429 GLY N C 1 ATOM 2747 O O . GLY A 1 350 ? 63.141 13.366 114.485 1.00 10.27 ? 429 GLY N O 1 ATOM 2748 N N . ARG A 1 351 ? 62.922 11.165 114.824 1.00 11.68 ? 430 ARG N N 1 ATOM 2749 C CA . ARG A 1 351 ? 61.615 11.192 114.222 1.00 12.72 ? 430 ARG N CA 1 ATOM 2750 C C . ARG A 1 351 ? 60.595 11.636 115.250 1.00 10.19 ? 430 ARG N C 1 ATOM 2751 O O . ARG A 1 351 ? 60.823 11.488 116.460 1.00 9.90 ? 430 ARG N O 1 ATOM 2752 C CB . ARG A 1 351 ? 61.302 9.815 113.680 1.00 15.25 ? 430 ARG N CB 1 ATOM 2753 C CG . ARG A 1 351 ? 62.008 9.591 112.343 1.00 19.70 ? 430 ARG N CG 1 ATOM 2754 C CD . ARG A 1 351 ? 61.252 8.604 111.459 1.00 25.25 ? 430 ARG N CD 1 ATOM 2755 N NE . ARG A 1 351 ? 61.716 8.727 110.092 1.00 27.78 ? 430 ARG N NE 1 ATOM 2756 C CZ . ARG A 1 351 ? 61.196 8.062 109.060 1.00 30.29 ? 430 ARG N CZ 1 ATOM 2757 N NH1 . ARG A 1 351 ? 60.152 7.249 109.156 1.00 33.91 ? 430 ARG N NH1 1 ATOM 2758 N NH2 . ARG A 1 351 ? 61.747 8.238 107.864 1.00 30.55 ? 430 ARG N NH2 1 ATOM 2759 N N . PRO A 1 352 ? 59.482 12.255 114.876 1.00 9.42 ? 431 PRO N N 1 ATOM 2760 C CA . PRO A 1 352 ? 59.059 12.586 113.531 1.00 9.65 ? 431 PRO N CA 1 ATOM 2761 C C . PRO A 1 352 ? 59.575 13.818 112.852 1.00 9.50 ? 431 PRO N C 1 ATOM 2762 O O . PRO A 1 352 ? 59.618 13.719 111.633 1.00 11.12 ? 431 PRO N O 1 ATOM 2763 C CB . PRO A 1 352 ? 57.592 12.629 113.580 1.00 7.64 ? 431 PRO N CB 1 ATOM 2764 C CG . PRO A 1 352 ? 57.378 13.281 114.891 1.00 5.67 ? 431 PRO N CG 1 ATOM 2765 C CD . PRO A 1 352 ? 58.439 12.663 115.809 1.00 8.61 ? 431 PRO N CD 1 ATOM 2766 N N . LYS A 1 353 ? 60.039 14.884 113.524 1.00 7.52 ? 432 LYS N N 1 ATOM 2767 C CA . LYS A 1 353 ? 60.400 16.128 112.859 1.00 10.36 ? 432 LYS N CA 1 ATOM 2768 C C . LYS A 1 353 ? 61.649 16.124 112.011 1.00 12.29 ? 432 LYS N C 1 ATOM 2769 O O . LYS A 1 353 ? 61.766 16.842 111.013 1.00 13.42 ? 432 LYS N O 1 ATOM 2770 C CB . LYS A 1 353 ? 60.578 17.274 113.841 1.00 11.56 ? 432 LYS N CB 1 ATOM 2771 C CG . LYS A 1 353 ? 59.278 17.737 114.457 1.00 10.87 ? 432 LYS N CG 1 ATOM 2772 C CD . LYS A 1 353 ? 58.344 18.593 113.593 1.00 11.68 ? 432 LYS N CD 1 ATOM 2773 C CE . LYS A 1 353 ? 56.965 18.456 114.192 1.00 12.12 ? 432 LYS N CE 1 ATOM 2774 N NZ . LYS A 1 353 ? 56.206 19.657 113.974 1.00 17.60 ? 432 LYS N NZ 1 ATOM 2775 N N . GLU A 1 354 ? 62.597 15.299 112.427 1.00 14.07 ? 433 GLU N N 1 ATOM 2776 C CA . GLU A 1 354 ? 63.876 15.157 111.763 1.00 17.10 ? 433 GLU N CA 1 ATOM 2777 C C . GLU A 1 354 ? 63.911 13.729 111.252 1.00 17.65 ? 433 GLU N C 1 ATOM 2778 O O . GLU A 1 354 ? 64.715 12.895 111.652 1.00 17.38 ? 433 GLU N O 1 ATOM 2779 C CB . GLU A 1 354 ? 64.985 15.384 112.752 1.00 18.24 ? 433 GLU N CB 1 ATOM 2780 C CG . GLU A 1 354 ? 64.939 16.761 113.313 1.00 19.94 ? 433 GLU N CG 1 ATOM 2781 C CD . GLU A 1 354 ? 66.233 17.082 114.001 1.00 20.97 ? 433 GLU N CD 1 ATOM 2782 O OE1 . GLU A 1 354 ? 66.471 16.552 115.073 1.00 22.80 ? 433 GLU N OE1 1 ATOM 2783 O OE2 . GLU A 1 354 ? 66.996 17.878 113.464 1.00 22.68 ? 433 GLU N OE2 1 ATOM 2784 N N . ASP A 1 355 ? 63.061 13.444 110.265 1.00 19.71 ? 434 ASP N N 1 ATOM 2785 C CA . ASP A 1 355 ? 62.810 12.071 109.837 1.00 18.20 ? 434 ASP N CA 1 ATOM 2786 C C . ASP A 1 355 ? 63.799 11.546 108.802 1.00 17.64 ? 434 ASP N C 1 ATOM 2787 O O . ASP A 1 355 ? 63.568 10.547 108.134 1.00 17.73 ? 434 ASP N O 1 ATOM 2788 C CB . ASP A 1 355 ? 61.344 12.042 109.332 1.00 18.81 ? 434 ASP N CB 1 ATOM 2789 C CG . ASP A 1 355 ? 61.140 12.645 107.944 1.00 20.94 ? 434 ASP N CG 1 ATOM 2790 O OD1 . ASP A 1 355 ? 61.876 13.575 107.549 1.00 22.34 ? 434 ASP N OD1 1 ATOM 2791 O OD2 . ASP A 1 355 ? 60.238 12.140 107.259 1.00 22.65 ? 434 ASP N OD2 1 ATOM 2792 N N . LYS A 1 356 ? 64.882 12.290 108.580 1.00 16.15 ? 435 LYS N N 1 ATOM 2793 C CA . LYS A 1 356 ? 65.975 11.870 107.712 1.00 16.49 ? 435 LYS N CA 1 ATOM 2794 C C . LYS A 1 356 ? 66.721 10.650 108.219 1.00 14.27 ? 435 LYS N C 1 ATOM 2795 O O . LYS A 1 356 ? 67.530 10.050 107.514 1.00 14.80 ? 435 LYS N O 1 ATOM 2796 C CB . LYS A 1 356 ? 66.946 13.017 107.562 1.00 22.26 ? 435 LYS N CB 1 ATOM 2797 C CG . LYS A 1 356 ? 67.241 13.101 106.090 1.00 28.68 ? 435 LYS N CG 1 ATOM 2798 C CD . LYS A 1 356 ? 67.860 14.401 105.608 1.00 32.46 ? 435 LYS N CD 1 ATOM 2799 C CE . LYS A 1 356 ? 68.007 14.229 104.097 1.00 35.98 ? 435 LYS N CE 1 ATOM 2800 N NZ . LYS A 1 356 ? 68.819 13.064 103.748 1.00 40.04 ? 435 LYS N NZ 1 ATOM 2801 N N . VAL A 1 357 ? 66.464 10.401 109.504 1.00 9.38 ? 436 VAL N N 1 ATOM 2802 C CA . VAL A 1 357 ? 66.981 9.306 110.280 1.00 6.39 ? 436 VAL N CA 1 ATOM 2803 C C . VAL A 1 357 ? 65.746 8.544 110.744 1.00 6.31 ? 436 VAL N C 1 ATOM 2804 O O . VAL A 1 357 ? 64.680 9.148 110.783 1.00 6.40 ? 436 VAL N O 1 ATOM 2805 C CB . VAL A 1 357 ? 67.783 9.854 111.487 1.00 6.14 ? 436 VAL N CB 1 ATOM 2806 C CG1 . VAL A 1 357 ? 68.931 10.683 110.967 1.00 3.90 ? 436 VAL N CG1 1 ATOM 2807 C CG2 . VAL A 1 357 ? 66.925 10.703 112.386 1.00 2.00 ? 436 VAL N CG2 1 ATOM 2808 N N . TRP A 1 358 ? 65.816 7.272 111.152 1.00 5.49 ? 437 TRP N N 1 ATOM 2809 C CA . TRP A 1 358 ? 64.638 6.551 111.598 1.00 4.08 ? 437 TRP N CA 1 ATOM 2810 C C . TRP A 1 358 ? 64.515 6.329 113.109 1.00 2.00 ? 437 TRP N C 1 ATOM 2811 O O . TRP A 1 358 ? 63.577 5.686 113.573 1.00 2.00 ? 437 TRP N O 1 ATOM 2812 C CB . TRP A 1 358 ? 64.620 5.236 110.891 1.00 8.95 ? 437 TRP N CB 1 ATOM 2813 C CG . TRP A 1 358 ? 64.574 5.277 109.370 1.00 12.02 ? 437 TRP N CG 1 ATOM 2814 C CD1 . TRP A 1 358 ? 65.681 5.528 108.593 1.00 13.88 ? 437 TRP N CD1 1 ATOM 2815 C CD2 . TRP A 1 358 ? 63.466 5.031 108.632 1.00 10.33 ? 437 TRP N CD2 1 ATOM 2816 N NE1 . TRP A 1 358 ? 65.263 5.438 107.356 1.00 13.00 ? 437 TRP N NE1 1 ATOM 2817 C CE2 . TRP A 1 358 ? 63.955 5.145 107.347 1.00 11.75 ? 437 TRP N CE2 1 ATOM 2818 C CE3 . TRP A 1 358 ? 62.157 4.741 108.859 1.00 10.48 ? 437 TRP N CE3 1 ATOM 2819 C CZ2 . TRP A 1 358 ? 63.127 4.965 106.265 1.00 12.48 ? 437 TRP N CZ2 1 ATOM 2820 C CZ3 . TRP A 1 358 ? 61.316 4.560 107.774 1.00 12.33 ? 437 TRP N CZ3 1 ATOM 2821 C CH2 . TRP A 1 358 ? 61.800 4.674 106.485 1.00 12.23 ? 437 TRP N CH2 1 ATOM 2822 N N . TRP A 1 359 ? 65.463 6.840 113.900 1.00 2.00 ? 438 TRP N N 1 ATOM 2823 C CA . TRP A 1 359 ? 65.483 6.674 115.339 1.00 2.00 ? 438 TRP N CA 1 ATOM 2824 C C . TRP A 1 359 ? 64.890 7.891 116.007 1.00 4.17 ? 438 TRP N C 1 ATOM 2825 O O . TRP A 1 359 ? 64.767 8.941 115.377 1.00 5.90 ? 438 TRP N O 1 ATOM 2826 C CB . TRP A 1 359 ? 66.911 6.489 115.880 1.00 2.00 ? 438 TRP N CB 1 ATOM 2827 C CG . TRP A 1 359 ? 68.009 7.476 115.447 1.00 2.00 ? 438 TRP N CG 1 ATOM 2828 C CD1 . TRP A 1 359 ? 68.904 7.072 114.501 1.00 2.00 ? 438 TRP N CD1 1 ATOM 2829 C CD2 . TRP A 1 359 ? 68.314 8.754 115.914 1.00 3.86 ? 438 TRP N CD2 1 ATOM 2830 N NE1 . TRP A 1 359 ? 69.758 8.049 114.363 1.00 2.57 ? 438 TRP N NE1 1 ATOM 2831 C CE2 . TRP A 1 359 ? 69.459 9.077 115.187 1.00 4.89 ? 438 TRP N CE2 1 ATOM 2832 C CE3 . TRP A 1 359 ? 67.861 9.699 116.814 1.00 2.68 ? 438 TRP N CE3 1 ATOM 2833 C CZ2 . TRP A 1 359 ? 70.126 10.295 115.346 1.00 2.85 ? 438 TRP N CZ2 1 ATOM 2834 C CZ3 . TRP A 1 359 ? 68.523 10.888 116.977 1.00 2.00 ? 438 TRP N CZ3 1 ATOM 2835 C CH2 . TRP A 1 359 ? 69.641 11.193 116.252 1.00 2.43 ? 438 TRP N CH2 1 ATOM 2836 N N . THR A 1 360 ? 64.469 7.735 117.249 1.00 6.57 ? 439 THR N N 1 ATOM 2837 C CA . THR A 1 360 ? 64.201 8.879 118.086 1.00 6.29 ? 439 THR N CA 1 ATOM 2838 C C . THR A 1 360 ? 64.992 8.691 119.372 1.00 7.12 ? 439 THR N C 1 ATOM 2839 O O . THR A 1 360 ? 64.799 7.698 120.071 1.00 8.25 ? 439 THR N O 1 ATOM 2840 C CB . THR A 1 360 ? 62.720 8.988 118.403 1.00 5.18 ? 439 THR N CB 1 ATOM 2841 O OG1 . THR A 1 360 ? 62.003 9.106 117.182 1.00 6.83 ? 439 THR N OG1 1 ATOM 2842 C CG2 . THR A 1 360 ? 62.444 10.202 119.231 1.00 6.98 ? 439 THR N CG2 1 ATOM 2843 N N . SER A 1 361 ? 65.996 9.515 119.645 1.00 5.95 ? 440 SER N N 1 ATOM 2844 C CA . SER A 1 361 ? 66.658 9.444 120.938 1.00 3.50 ? 440 SER N CA 1 ATOM 2845 C C . SER A 1 361 ? 66.413 10.851 121.441 1.00 4.19 ? 440 SER N C 1 ATOM 2846 O O . SER A 1 361 ? 65.561 11.617 120.962 1.00 5.12 ? 440 SER N O 1 ATOM 2847 C CB . SER A 1 361 ? 68.187 9.155 120.790 1.00 4.99 ? 440 SER N CB 1 ATOM 2848 O OG . SER A 1 361 ? 69.042 9.232 121.967 1.00 5.06 ? 440 SER N OG 1 ATOM 2849 N N . ASN A 1 362 ? 67.178 11.190 122.440 1.00 3.14 ? 441 ASN N N 1 ATOM 2850 C CA . ASN A 1 362 ? 67.093 12.482 123.023 1.00 2.87 ? 441 ASN N CA 1 ATOM 2851 C C . ASN A 1 362 ? 68.384 12.610 123.815 1.00 4.73 ? 441 ASN N C 1 ATOM 2852 O O . ASN A 1 362 ? 69.138 11.650 124.016 1.00 5.48 ? 441 ASN N O 1 ATOM 2853 C CB . ASN A 1 362 ? 65.882 12.608 123.966 1.00 4.59 ? 441 ASN N CB 1 ATOM 2854 C CG . ASN A 1 362 ? 66.044 11.783 125.242 1.00 5.62 ? 441 ASN N CG 1 ATOM 2855 O OD1 . ASN A 1 362 ? 66.145 12.259 126.377 1.00 5.66 ? 441 ASN N OD1 1 ATOM 2856 N ND2 . ASN A 1 362 ? 66.061 10.481 125.010 1.00 6.43 ? 441 ASN N ND2 1 ATOM 2857 N N . SER A 1 363 ? 68.617 13.859 124.195 1.00 3.87 ? 442 SER N N 1 ATOM 2858 C CA . SER A 1 363 ? 69.743 14.266 124.998 1.00 4.76 ? 442 SER N CA 1 ATOM 2859 C C . SER A 1 363 ? 69.117 14.718 126.321 1.00 4.34 ? 442 SER N C 1 ATOM 2860 O O . SER A 1 363 ? 67.879 14.620 126.414 1.00 7.30 ? 442 SER N O 1 ATOM 2861 C CB . SER A 1 363 ? 70.354 15.359 124.238 1.00 4.64 ? 442 SER N CB 1 ATOM 2862 O OG . SER A 1 363 ? 71.344 15.928 125.046 1.00 6.35 ? 442 SER N OG 1 ATOM 2863 N N . ILE A 1 364 ? 69.832 15.224 127.350 1.00 3.18 ? 443 ILE N N 1 ATOM 2864 C CA . ILE A 1 364 ? 69.222 15.816 128.587 1.00 2.00 ? 443 ILE N CA 1 ATOM 2865 C C . ILE A 1 364 ? 69.927 17.136 128.959 1.00 2.68 ? 443 ILE N C 1 ATOM 2866 O O . ILE A 1 364 ? 71.157 17.228 128.767 1.00 4.54 ? 443 ILE N O 1 ATOM 2867 C CB . ILE A 1 364 ? 69.370 14.904 129.819 1.00 3.43 ? 443 ILE N CB 1 ATOM 2868 C CG1 . ILE A 1 364 ? 68.646 13.675 129.582 1.00 2.00 ? 443 ILE N CG1 1 ATOM 2869 C CG2 . ILE A 1 364 ? 68.756 15.485 131.071 1.00 2.00 ? 443 ILE N CG2 1 ATOM 2870 C CD1 . ILE A 1 364 ? 69.441 12.648 130.350 1.00 2.35 ? 443 ILE N CD1 1 ATOM 2871 N N . VAL A 1 365 ? 69.240 18.165 129.462 1.00 3.22 ? 444 VAL N N 1 ATOM 2872 C CA . VAL A 1 365 ? 69.913 19.357 129.995 1.00 4.80 ? 444 VAL N CA 1 ATOM 2873 C C . VAL A 1 365 ? 69.369 19.547 131.404 1.00 5.06 ? 444 VAL N C 1 ATOM 2874 O O . VAL A 1 365 ? 68.155 19.355 131.555 1.00 4.54 ? 444 VAL N O 1 ATOM 2875 C CB . VAL A 1 365 ? 69.611 20.681 129.265 1.00 2.00 ? 444 VAL N CB 1 ATOM 2876 C CG1 . VAL A 1 365 ? 70.725 21.662 129.591 1.00 2.81 ? 444 VAL N CG1 1 ATOM 2877 C CG2 . VAL A 1 365 ? 69.638 20.541 127.792 1.00 2.00 ? 444 VAL N CG2 1 ATOM 2878 N N . SER A 1 366 ? 70.170 19.879 132.410 1.00 3.89 ? 445 SER N N 1 ATOM 2879 C CA . SER A 1 366 ? 69.698 20.111 133.750 1.00 6.18 ? 445 SER N CA 1 ATOM 2880 C C . SER A 1 366 ? 70.219 21.449 134.220 1.00 6.99 ? 445 SER N C 1 ATOM 2881 O O . SER A 1 366 ? 71.361 21.849 133.942 1.00 9.18 ? 445 SER N O 1 ATOM 2882 C CB . SER A 1 366 ? 70.237 19.122 134.733 1.00 4.60 ? 445 SER N CB 1 ATOM 2883 O OG . SER A 1 366 ? 69.383 18.077 135.118 1.00 6.97 ? 445 SER N OG 1 ATOM 2884 N N . MET A 1 367 ? 69.433 22.094 135.066 1.00 4.50 ? 446 MET N N 1 ATOM 2885 C CA . MET A 1 367 ? 69.811 23.368 135.621 1.00 2.86 ? 446 MET N CA 1 ATOM 2886 C C . MET A 1 367 ? 69.343 23.388 137.046 1.00 3.45 ? 446 MET N C 1 ATOM 2887 O O . MET A 1 367 ? 68.334 22.761 137.337 1.00 5.32 ? 446 MET N O 1 ATOM 2888 C CB . MET A 1 367 ? 69.098 24.432 134.926 1.00 3.93 ? 446 MET N CB 1 ATOM 2889 C CG . MET A 1 367 ? 69.991 25.528 134.510 1.00 5.03 ? 446 MET N CG 1 ATOM 2890 S SD . MET A 1 367 ? 69.910 25.346 132.739 1.00 6.89 ? 446 MET N SD 1 ATOM 2891 C CE . MET A 1 367 ? 70.523 26.981 132.419 1.00 4.06 ? 446 MET N CE 1 ATOM 2892 N N . CYS A 1 368 ? 69.977 24.047 137.967 1.00 2.00 ? 447 CYS N N 1 ATOM 2893 C CA . CYS A 1 368 ? 69.435 24.139 139.291 1.00 2.96 ? 447 CYS N CA 1 ATOM 2894 C C . CYS A 1 368 ? 69.250 25.635 139.531 1.00 4.93 ? 447 CYS N C 1 ATOM 2895 O O . CYS A 1 368 ? 69.526 26.409 138.599 1.00 8.42 ? 447 CYS N O 1 ATOM 2896 C CB . CYS A 1 368 ? 70.410 23.552 140.295 1.00 3.04 ? 447 CYS N CB 1 ATOM 2897 S SG . CYS A 1 368 ? 70.251 21.804 140.625 1.00 4.22 ? 447 CYS N SG 1 ATOM 2898 N N . SER A 1 369 ? 68.861 26.174 140.699 1.00 3.41 ? 448 SER N N 1 ATOM 2899 C CA . SER A 1 369 ? 68.534 27.587 140.894 1.00 2.07 ? 448 SER N CA 1 ATOM 2900 C C . SER A 1 369 ? 69.540 28.308 141.729 1.00 2.00 ? 448 SER N C 1 ATOM 2901 O O . SER A 1 369 ? 70.040 27.787 142.730 1.00 5.98 ? 448 SER N O 1 ATOM 2902 C CB . SER A 1 369 ? 67.178 27.732 141.562 1.00 2.00 ? 448 SER N CB 1 ATOM 2903 O OG . SER A 1 369 ? 67.020 27.395 142.947 1.00 6.57 ? 448 SER N OG 1 ATOM 2904 N N . SER A 1 370 ? 69.835 29.489 141.259 1.00 2.00 ? 449 SER N N 1 ATOM 2905 C CA . SER A 1 370 ? 70.794 30.325 141.919 1.00 3.65 ? 449 SER N CA 1 ATOM 2906 C C . SER A 1 370 ? 70.109 31.489 142.589 1.00 4.63 ? 449 SER N C 1 ATOM 2907 O O . SER A 1 370 ? 69.133 32.021 142.068 1.00 5.06 ? 449 SER N O 1 ATOM 2908 C CB . SER A 1 370 ? 71.754 30.782 140.875 1.00 4.15 ? 449 SER N CB 1 ATOM 2909 O OG . SER A 1 370 ? 72.815 31.415 141.506 1.00 10.25 ? 449 SER N OG 1 ATOM 2910 N N . THR A 1 371 ? 70.532 31.963 143.747 1.00 7.70 ? 450 THR N N 1 ATOM 2911 C CA . THR A 1 371 ? 69.966 33.150 144.398 1.00 8.38 ? 450 THR N CA 1 ATOM 2912 C C . THR A 1 371 ? 70.476 34.416 143.730 1.00 12.80 ? 450 THR N C 1 ATOM 2913 O O . THR A 1 371 ? 69.916 35.496 143.845 1.00 17.70 ? 450 THR N O 1 ATOM 2914 C CB . THR A 1 371 ? 70.383 33.146 145.835 1.00 6.77 ? 450 THR N CB 1 ATOM 2915 O OG1 . THR A 1 371 ? 71.801 33.022 145.803 1.00 8.87 ? 450 THR N OG1 1 ATOM 2916 C CG2 . THR A 1 371 ? 69.818 32.001 146.646 1.00 5.50 ? 450 THR N CG2 1 ATOM 2917 N N . GLU A 1 372 ? 71.668 34.293 143.150 1.00 14.53 ? 451 GLU N N 1 ATOM 2918 C CA . GLU A 1 372 ? 72.342 35.272 142.309 1.00 15.67 ? 451 GLU N CA 1 ATOM 2919 C C . GLU A 1 372 ? 71.537 35.635 141.081 1.00 13.43 ? 451 GLU N C 1 ATOM 2920 O O . GLU A 1 372 ? 70.469 35.057 140.809 1.00 14.68 ? 451 GLU N O 1 ATOM 2921 C CB . GLU A 1 372 ? 73.642 34.684 141.821 1.00 21.92 ? 451 GLU N CB 1 ATOM 2922 C CG . GLU A 1 372 ? 74.657 34.477 142.929 1.00 29.15 ? 451 GLU N CG 1 ATOM 2923 C CD . GLU A 1 372 ? 74.964 35.822 143.574 1.00 33.62 ? 451 GLU N CD 1 ATOM 2924 O OE1 . GLU A 1 372 ? 75.479 36.701 142.865 1.00 36.11 ? 451 GLU N OE1 1 ATOM 2925 O OE2 . GLU A 1 372 ? 74.644 35.991 144.757 1.00 36.92 ? 451 GLU N OE2 1 ATOM 2926 N N . PHE A 1 373 ? 72.040 36.600 140.305 1.00 9.49 ? 452 PHE N N 1 ATOM 2927 C CA . PHE A 1 373 ? 71.481 36.744 138.979 1.00 8.68 ? 452 PHE N CA 1 ATOM 2928 C C . PHE A 1 373 ? 72.644 36.364 138.125 1.00 8.92 ? 452 PHE N C 1 ATOM 2929 O O . PHE A 1 373 ? 73.662 37.053 138.063 1.00 12.30 ? 452 PHE N O 1 ATOM 2930 C CB . PHE A 1 373 ? 71.089 38.131 138.663 1.00 5.40 ? 452 PHE N CB 1 ATOM 2931 C CG . PHE A 1 373 ? 69.819 38.452 139.433 1.00 6.01 ? 452 PHE N CG 1 ATOM 2932 C CD1 . PHE A 1 373 ? 68.608 37.992 138.937 1.00 2.89 ? 452 PHE N CD1 1 ATOM 2933 C CD2 . PHE A 1 373 ? 69.883 39.151 140.612 1.00 3.80 ? 452 PHE N CD2 1 ATOM 2934 C CE1 . PHE A 1 373 ? 67.439 38.220 139.619 1.00 2.59 ? 452 PHE N CE1 1 ATOM 2935 C CE2 . PHE A 1 373 ? 68.718 39.387 141.311 1.00 4.41 ? 452 PHE N CE2 1 ATOM 2936 C CZ . PHE A 1 373 ? 67.504 38.923 140.817 1.00 3.79 ? 452 PHE N CZ 1 ATOM 2937 N N . LEU A 1 374 ? 72.626 35.145 137.627 1.00 7.21 ? 453 LEU N N 1 ATOM 2938 C CA . LEU A 1 374 ? 73.674 34.772 136.744 1.00 5.26 ? 453 LEU N CA 1 ATOM 2939 C C . LEU A 1 374 ? 73.077 35.021 135.380 1.00 6.89 ? 453 LEU N C 1 ATOM 2940 O O . LEU A 1 374 ? 71.844 35.015 135.205 1.00 6.68 ? 453 LEU N O 1 ATOM 2941 C CB . LEU A 1 374 ? 73.971 33.365 136.956 1.00 2.00 ? 453 LEU N CB 1 ATOM 2942 C CG . LEU A 1 374 ? 74.273 33.007 138.320 1.00 2.09 ? 453 LEU N CG 1 ATOM 2943 C CD1 . LEU A 1 374 ? 74.339 31.540 138.274 1.00 3.15 ? 453 LEU N CD1 1 ATOM 2944 C CD2 . LEU A 1 374 ? 75.566 33.559 138.810 1.00 2.00 ? 453 LEU N CD2 1 ATOM 2945 N N . GLY A 1 375 ? 73.985 35.368 134.477 1.00 6.16 ? 454 GLY N N 1 ATOM 2946 C CA . GLY A 1 375 ? 73.673 35.620 133.102 1.00 5.66 ? 454 GLY N CA 1 ATOM 2947 C C . GLY A 1 375 ? 73.237 34.343 132.430 1.00 6.05 ? 454 GLY N C 1 ATOM 2948 O O . GLY A 1 375 ? 73.576 33.267 132.923 1.00 9.17 ? 454 GLY N O 1 ATOM 2949 N N . GLN A 1 376 ? 72.602 34.414 131.271 1.00 5.87 ? 455 GLN N N 1 ATOM 2950 C CA . GLN A 1 376 ? 72.076 33.238 130.604 1.00 5.07 ? 455 GLN N CA 1 ATOM 2951 C C . GLN A 1 376 ? 72.792 32.706 129.386 1.00 4.32 ? 455 GLN N C 1 ATOM 2952 O O . GLN A 1 376 ? 73.427 33.497 128.703 1.00 5.86 ? 455 GLN N O 1 ATOM 2953 C CB . GLN A 1 376 ? 70.674 33.513 130.180 1.00 7.10 ? 455 GLN N CB 1 ATOM 2954 C CG . GLN A 1 376 ? 70.531 34.602 129.079 1.00 7.72 ? 455 GLN N CG 1 ATOM 2955 C CD . GLN A 1 376 ? 69.072 34.924 128.723 1.00 8.07 ? 455 GLN N CD 1 ATOM 2956 O OE1 . GLN A 1 376 ? 68.709 35.289 127.594 1.00 7.65 ? 455 GLN N OE1 1 ATOM 2957 N NE2 . GLN A 1 376 ? 68.160 34.815 129.677 1.00 6.88 ? 455 GLN N NE2 1 ATOM 2958 N N . TRP A 1 377 ? 72.669 31.405 129.056 1.00 4.06 ? 456 TRP N N 1 ATOM 2959 C CA . TRP A 1 377 ? 73.138 30.840 127.794 1.00 3.85 ? 456 TRP N CA 1 ATOM 2960 C C . TRP A 1 377 ? 72.070 29.835 127.376 1.00 2.93 ? 456 TRP N C 1 ATOM 2961 O O . TRP A 1 377 ? 71.480 29.222 128.258 1.00 2.00 ? 456 TRP N O 1 ATOM 2962 C CB . TRP A 1 377 ? 74.489 30.107 127.973 1.00 2.00 ? 456 TRP N CB 1 ATOM 2963 C CG . TRP A 1 377 ? 75.471 30.062 126.813 1.00 2.00 ? 456 TRP N CG 1 ATOM 2964 C CD1 . TRP A 1 377 ? 75.278 30.781 125.683 1.00 2.00 ? 456 TRP N CD1 1 ATOM 2965 C CD2 . TRP A 1 377 ? 76.617 29.344 126.767 1.00 2.34 ? 456 TRP N CD2 1 ATOM 2966 N NE1 . TRP A 1 377 ? 76.290 30.537 124.912 1.00 2.83 ? 456 TRP N NE1 1 ATOM 2967 C CE2 . TRP A 1 377 ? 77.111 29.686 125.508 1.00 3.20 ? 456 TRP N CE2 1 ATOM 2968 C CE3 . TRP A 1 377 ? 77.300 28.465 127.586 1.00 2.00 ? 456 TRP N CE3 1 ATOM 2969 C CZ2 . TRP A 1 377 ? 78.289 29.189 124.992 1.00 3.53 ? 456 TRP N CZ2 1 ATOM 2970 C CZ3 . TRP A 1 377 ? 78.479 27.959 127.075 1.00 2.28 ? 456 TRP N CZ3 1 ATOM 2971 C CH2 . TRP A 1 377 ? 78.974 28.309 125.811 1.00 3.58 ? 456 TRP N CH2 1 ATOM 2972 N N . ASP A 1 378 ? 72.052 29.682 126.066 1.00 3.28 ? 457 ASP N N 1 ATOM 2973 C CA . ASP A 1 378 ? 71.251 28.627 125.477 1.00 4.73 ? 457 ASP N CA 1 ATOM 2974 C C . ASP A 1 378 ? 72.019 27.281 125.414 1.00 7.60 ? 457 ASP N C 1 ATOM 2975 O O . ASP A 1 378 ? 73.253 27.355 125.340 1.00 10.86 ? 457 ASP N O 1 ATOM 2976 C CB . ASP A 1 378 ? 70.841 29.086 124.099 1.00 6.24 ? 457 ASP N CB 1 ATOM 2977 C CG . ASP A 1 378 ? 71.946 29.147 123.054 1.00 8.23 ? 457 ASP N CG 1 ATOM 2978 O OD1 . ASP A 1 378 ? 72.923 29.866 123.271 1.00 10.74 ? 457 ASP N OD1 1 ATOM 2979 O OD2 . ASP A 1 378 ? 71.816 28.441 122.047 1.00 9.79 ? 457 ASP N OD2 1 ATOM 2980 N N . TRP A 1 379 ? 71.412 26.146 125.523 1.00 5.65 ? 458 TRP N N 1 ATOM 2981 C CA . TRP A 1 379 ? 72.002 24.793 125.600 1.00 4.61 ? 458 TRP N CA 1 ATOM 2982 C C . TRP A 1 379 ? 71.328 23.766 124.659 1.00 4.83 ? 458 TRP N C 1 ATOM 2983 O O . TRP A 1 379 ? 70.409 23.058 125.076 1.00 2.88 ? 458 TRP N O 1 ATOM 2984 C CB . TRP A 1 379 ? 71.904 24.307 127.064 1.00 2.61 ? 458 TRP N CB 1 ATOM 2985 C CG . TRP A 1 379 ? 72.572 25.299 128.016 1.00 4.69 ? 458 TRP N CG 1 ATOM 2986 C CD1 . TRP A 1 379 ? 71.981 26.356 128.585 1.00 5.28 ? 458 TRP N CD1 1 ATOM 2987 C CD2 . TRP A 1 379 ? 73.922 25.240 128.421 1.00 6.54 ? 458 TRP N CD2 1 ATOM 2988 N NE1 . TRP A 1 379 ? 72.967 27.008 129.334 1.00 3.58 ? 458 TRP N NE1 1 ATOM 2989 C CE2 . TRP A 1 379 ? 74.108 26.348 129.224 1.00 6.13 ? 458 TRP N CE2 1 ATOM 2990 C CE3 . TRP A 1 379 ? 75.007 24.375 128.175 1.00 4.68 ? 458 TRP N CE3 1 ATOM 2991 C CZ2 . TRP A 1 379 ? 75.334 26.665 129.792 1.00 7.91 ? 458 TRP N CZ2 1 ATOM 2992 C CZ3 . TRP A 1 379 ? 76.239 24.701 128.764 1.00 2.00 ? 458 TRP N CZ3 1 ATOM 2993 C CH2 . TRP A 1 379 ? 76.391 25.797 129.533 1.00 5.16 ? 458 TRP N CH2 1 ATOM 2994 N N . PRO A 1 380 ? 71.839 23.779 123.428 1.00 6.18 ? 459 PRO N N 1 ATOM 2995 C CA . PRO A 1 380 ? 71.513 22.864 122.324 1.00 8.09 ? 459 PRO N CA 1 ATOM 2996 C C . PRO A 1 380 ? 71.975 21.443 122.530 1.00 11.24 ? 459 PRO N C 1 ATOM 2997 O O . PRO A 1 380 ? 73.101 21.215 123.062 1.00 12.67 ? 459 PRO N O 1 ATOM 2998 C CB . PRO A 1 380 ? 72.341 23.359 121.153 1.00 7.98 ? 459 PRO N CB 1 ATOM 2999 C CG . PRO A 1 380 ? 73.137 24.554 121.639 1.00 10.11 ? 459 PRO N CG 1 ATOM 3000 C CD . PRO A 1 380 ? 72.787 24.817 123.067 1.00 8.82 ? 459 PRO N CD 1 ATOM 3001 N N . ASP A 1 381 ? 71.146 20.504 122.101 1.00 15.76 ? 460 ASP N N 1 ATOM 3002 C CA . ASP A 1 381 ? 71.542 19.094 122.098 1.00 17.40 ? 460 ASP N CA 1 ATOM 3003 C C . ASP A 1 381 ? 72.901 19.068 121.418 1.00 21.23 ? 460 ASP N C 1 ATOM 3004 O O . ASP A 1 381 ? 73.909 18.599 121.970 1.00 28.00 ? 460 ASP N O 1 ATOM 3005 C CB . ASP A 1 381 ? 70.536 18.279 121.286 1.00 15.25 ? 460 ASP N CB 1 ATOM 3006 C CG . ASP A 1 381 ? 71.052 16.910 120.874 1.00 11.01 ? 460 ASP N CG 1 ATOM 3007 O OD1 . ASP A 1 381 ? 71.109 15.969 121.754 1.00 11.35 ? 460 ASP N OD1 1 ATOM 3008 O OD2 . ASP A 1 381 ? 71.419 16.722 119.643 1.00 7.50 ? 460 ASP N OD2 1 ATOM 3009 N N . GLY A 1 382 ? 72.881 19.566 120.202 1.00 26.00 ? 461 GLY N N 1 ATOM 3010 C CA . GLY A 1 382 ? 74.110 19.745 119.452 1.00 30.40 ? 461 GLY N CA 1 ATOM 3011 C C . GLY A 1 382 ? 74.404 18.818 118.257 1.00 34.40 ? 461 GLY N C 1 ATOM 3012 O O . GLY A 1 382 ? 75.289 19.086 117.453 1.00 36.01 ? 461 GLY N O 1 ATOM 3013 N N . ALA A 1 383 ? 73.751 17.729 118.023 1.00 32.75 ? 462 ALA N N 1 ATOM 3014 C CA . ALA A 1 383 ? 74.206 16.898 116.883 1.00 28.95 ? 462 ALA N CA 1 ATOM 3015 C C . ALA A 1 383 ? 73.694 17.365 115.516 1.00 28.33 ? 462 ALA N C 1 ATOM 3016 O O . ALA A 1 383 ? 72.678 18.046 115.394 1.00 30.33 ? 462 ALA N O 1 ATOM 3017 C CB . ALA A 1 383 ? 73.724 15.479 117.066 1.00 32.71 ? 462 ALA N CB 1 ATOM 3018 N N . LYS A 1 384 ? 74.422 16.974 114.492 1.00 26.80 ? 463 LYS N N 1 ATOM 3019 C CA . LYS A 1 384 ? 74.055 17.301 113.104 1.00 28.13 ? 463 LYS N CA 1 ATOM 3020 C C . LYS A 1 384 ? 73.466 16.041 112.457 1.00 26.15 ? 463 LYS N C 1 ATOM 3021 O O . LYS A 1 384 ? 74.196 15.083 112.165 1.00 23.42 ? 463 LYS N O 1 ATOM 3022 C CB . LYS A 1 384 ? 75.307 17.792 112.320 1.00 29.83 ? 463 LYS N CB 1 ATOM 3023 C CG . LYS A 1 384 ? 76.257 18.620 113.210 1.00 31.67 ? 463 LYS N CG 1 ATOM 3024 C CD . LYS A 1 384 ? 76.389 20.159 112.932 1.00 35.13 ? 463 LYS N CD 1 ATOM 3025 C CE . LYS A 1 384 ? 75.295 20.905 113.791 1.00 37.62 ? 463 LYS N CE 1 ATOM 3026 N NZ . LYS A 1 384 ? 75.228 22.396 113.712 1.00 42.22 ? 463 LYS N NZ 1 ATOM 3027 N N . ILE A 1 385 ? 72.141 16.069 112.242 1.00 24.85 ? 464 ILE N N 1 ATOM 3028 C CA . ILE A 1 385 ? 71.427 14.905 111.675 1.00 24.62 ? 464 ILE N CA 1 ATOM 3029 C C . ILE A 1 385 ? 72.063 14.478 110.372 1.00 23.58 ? 464 ILE N C 1 ATOM 3030 O O . ILE A 1 385 ? 71.723 13.433 109.793 1.00 26.70 ? 464 ILE N O 1 ATOM 3031 C CB . ILE A 1 385 ? 69.929 15.184 111.481 1.00 25.46 ? 464 ILE N CB 1 ATOM 3032 C CG1 . ILE A 1 385 ? 69.122 14.786 112.716 1.00 25.65 ? 464 ILE N CG1 1 ATOM 3033 C CG2 . ILE A 1 385 ? 69.304 14.399 110.320 1.00 27.16 ? 464 ILE N CG2 1 ATOM 3034 C CD1 . ILE A 1 385 ? 69.099 13.268 112.940 1.00 24.07 ? 464 ILE N CD1 1 ATOM 3035 N N . GLU A 1 386 ? 73.003 15.246 109.901 1.00 20.79 ? 465 GLU N N 1 ATOM 3036 C CA . GLU A 1 386 ? 73.605 14.879 108.649 1.00 20.95 ? 465 GLU N CA 1 ATOM 3037 C C . GLU A 1 386 ? 74.835 14.034 108.825 1.00 22.06 ? 465 GLU N C 1 ATOM 3038 O O . GLU A 1 386 ? 75.426 13.534 107.861 1.00 21.88 ? 465 GLU N O 1 ATOM 3039 C CB . GLU A 1 386 ? 73.890 16.097 107.820 1.00 18.26 ? 465 GLU N CB 1 ATOM 3040 C CG . GLU A 1 386 ? 72.620 16.461 107.047 1.00 14.60 ? 465 GLU N CG 1 ATOM 3041 C CD . GLU A 1 386 ? 72.855 16.934 105.629 1.00 13.07 ? 465 GLU N CD 1 ATOM 3042 O OE1 . GLU A 1 386 ? 74.049 16.967 105.153 1.00 13.04 ? 465 GLU N OE1 1 ATOM 3043 O OE2 . GLU A 1 386 ? 71.851 17.302 104.908 1.00 11.64 ? 465 GLU N OE2 1 ATOM 3044 N N . TYR A 1 387 ? 75.299 13.800 109.992 1.00 21.69 ? 466 TYR N N 1 ATOM 3045 C CA . TYR A 1 387 ? 76.447 12.912 110.016 1.00 20.16 ? 466 TYR N CA 1 ATOM 3046 C C . TYR A 1 387 ? 76.033 11.479 110.310 1.00 21.23 ? 466 TYR N C 1 ATOM 3047 O O . TYR A 1 387 ? 76.848 10.604 110.578 1.00 20.86 ? 466 TYR N O 1 ATOM 3048 C CB . TYR A 1 387 ? 77.449 13.210 111.122 1.00 19.01 ? 466 TYR N CB 1 ATOM 3049 C CG . TYR A 1 387 ? 78.156 14.567 111.116 1.00 19.19 ? 466 TYR N CG 1 ATOM 3050 C CD1 . TYR A 1 387 ? 78.506 15.222 109.922 1.00 22.13 ? 466 TYR N CD1 1 ATOM 3051 C CD2 . TYR A 1 387 ? 78.464 15.147 112.348 1.00 20.67 ? 466 TYR N CD2 1 ATOM 3052 C CE1 . TYR A 1 387 ? 79.173 16.463 109.979 1.00 21.81 ? 466 TYR N CE1 1 ATOM 3053 C CE2 . TYR A 1 387 ? 79.126 16.378 112.402 1.00 19.63 ? 466 TYR N CE2 1 ATOM 3054 C CZ . TYR A 1 387 ? 79.483 17.037 111.223 1.00 21.02 ? 466 TYR N CZ 1 ATOM 3055 O OH . TYR A 1 387 ? 80.132 18.232 111.281 1.00 24.69 ? 466 TYR N OH 1 ATOM 3056 N N . PHE A 1 388 ? 74.813 11.207 110.289 1.00 22.49 ? 467 PHE N N 1 ATOM 3057 C CA . PHE A 1 388 ? 74.368 9.872 110.619 1.00 23.05 ? 467 PHE N CA 1 ATOM 3058 C C . PHE A 1 388 ? 73.858 9.155 109.402 1.00 27.95 ? 467 PHE N C 1 ATOM 3059 O O . PHE A 1 388 ? 73.336 8.051 109.533 1.00 29.04 ? 467 PHE N O 1 ATOM 3060 C CB . PHE A 1 388 ? 73.202 9.956 111.581 1.00 16.73 ? 467 PHE N CB 1 ATOM 3061 C CG . PHE A 1 388 ? 73.609 10.417 112.947 1.00 14.83 ? 467 PHE N CG 1 ATOM 3062 C CD1 . PHE A 1 388 ? 73.750 11.775 113.189 1.00 14.93 ? 467 PHE N CD1 1 ATOM 3063 C CD2 . PHE A 1 388 ? 73.840 9.475 113.938 1.00 11.20 ? 467 PHE N CD2 1 ATOM 3064 C CE1 . PHE A 1 388 ? 74.136 12.200 114.452 1.00 9.12 ? 467 PHE N CE1 1 ATOM 3065 C CE2 . PHE A 1 388 ? 74.223 9.895 115.198 1.00 8.45 ? 467 PHE N CE2 1 ATOM 3066 C CZ . PHE A 1 388 ? 74.373 11.258 115.458 1.00 7.90 ? 467 PHE N CZ 1 ATOM 3067 N N . LEU A 1 389 ? 74.015 9.870 108.282 1.00 31.62 ? 468 LEU N N 1 ATOM 3068 C CA . LEU A 1 389 ? 73.568 9.476 106.923 1.00 32.13 ? 468 LEU N CA 1 ATOM 3069 C C . LEU A 1 389 ? 74.750 8.938 106.116 1.00 36.14 ? 468 LEU N C 1 ATOM 3070 O O . LEU A 1 389 ? 74.350 8.033 105.427 1.00 40.78 ? 468 LEU N O 1 ATOM 3071 C CB . LEU A 1 389 ? 73.016 10.709 106.159 1.00 28.86 ? 468 LEU N CB 1 ATOM 3072 C CG . LEU A 1 389 ? 71.873 11.509 106.806 1.00 25.08 ? 468 LEU N CG 1 ATOM 3073 C CD1 . LEU A 1 389 ? 71.761 12.905 106.180 1.00 22.70 ? 468 LEU N CD1 1 ATOM 3074 C CD2 . LEU A 1 389 ? 70.503 10.841 106.639 1.00 24.40 ? 468 LEU N CD2 1 ATOM 3075 O OXT . LEU A 1 389 ? 75.714 9.665 106.244 1.00 40.55 ? 468 LEU N OXT 1 ATOM 3076 N N . ASP B 2 1 ? 57.016 12.329 100.893 1.00 24.92 ? 1 ASP L N 1 ATOM 3077 C CA . ASP B 2 1 ? 56.580 13.695 101.141 1.00 22.14 ? 1 ASP L CA 1 ATOM 3078 C C . ASP B 2 1 ? 55.102 13.501 101.444 1.00 23.33 ? 1 ASP L C 1 ATOM 3079 O O . ASP B 2 1 ? 54.544 12.649 100.735 1.00 22.84 ? 1 ASP L O 1 ATOM 3080 C CB . ASP B 2 1 ? 56.736 14.573 99.886 1.00 22.67 ? 1 ASP L CB 1 ATOM 3081 C CG . ASP B 2 1 ? 58.128 15.135 99.545 1.00 21.24 ? 1 ASP L CG 1 ATOM 3082 O OD1 . ASP B 2 1 ? 59.165 14.563 99.913 1.00 20.63 ? 1 ASP L OD1 1 ATOM 3083 O OD2 . ASP B 2 1 ? 58.158 16.170 98.875 1.00 21.01 ? 1 ASP L OD2 1 ATOM 3084 N N . ILE B 2 2 ? 54.431 14.148 102.413 1.00 22.54 ? 2 ILE L N 1 ATOM 3085 C CA . ILE B 2 2 ? 53.032 13.791 102.597 1.00 21.39 ? 2 ILE L CA 1 ATOM 3086 C C . ILE B 2 2 ? 52.225 14.641 101.644 1.00 21.68 ? 2 ILE L C 1 ATOM 3087 O O . ILE B 2 2 ? 52.401 15.857 101.610 1.00 22.37 ? 2 ILE L O 1 ATOM 3088 C CB . ILE B 2 2 ? 52.683 13.995 104.090 1.00 21.74 ? 2 ILE L CB 1 ATOM 3089 C CG1 . ILE B 2 2 ? 53.551 12.977 104.842 1.00 21.21 ? 2 ILE L CG1 1 ATOM 3090 C CG2 . ILE B 2 2 ? 51.207 13.755 104.407 1.00 21.07 ? 2 ILE L CG2 1 ATOM 3091 C CD1 . ILE B 2 2 ? 53.572 12.993 106.380 1.00 23.96 ? 2 ILE L CD1 1 ATOM 3092 N N . VAL B 2 3 ? 51.409 14.023 100.800 1.00 21.41 ? 3 VAL L N 1 ATOM 3093 C CA . VAL B 2 3 ? 50.603 14.751 99.850 1.00 23.80 ? 3 VAL L CA 1 ATOM 3094 C C . VAL B 2 3 ? 49.259 15.185 100.439 1.00 22.73 ? 3 VAL L C 1 ATOM 3095 O O . VAL B 2 3 ? 48.542 14.342 100.974 1.00 22.06 ? 3 VAL L O 1 ATOM 3096 C CB . VAL B 2 3 ? 50.549 13.780 98.664 1.00 22.25 ? 3 VAL L CB 1 ATOM 3097 C CG1 . VAL B 2 3 ? 49.400 13.918 97.673 1.00 21.85 ? 3 VAL L CG1 1 ATOM 3098 C CG2 . VAL B 2 3 ? 51.818 14.108 97.954 1.00 23.81 ? 3 VAL L CG2 1 ATOM 3099 N N . MET B 2 4 ? 48.991 16.506 100.464 1.00 22.94 ? 4 MET L N 1 ATOM 3100 C CA . MET B 2 4 ? 47.717 17.100 100.895 1.00 20.92 ? 4 MET L CA 1 ATOM 3101 C C . MET B 2 4 ? 46.893 17.375 99.646 1.00 22.02 ? 4 MET L C 1 ATOM 3102 O O . MET B 2 4 ? 47.357 17.971 98.658 1.00 23.40 ? 4 MET L O 1 ATOM 3103 C CB . MET B 2 4 ? 47.909 18.419 101.639 1.00 19.82 ? 4 MET L CB 1 ATOM 3104 C CG . MET B 2 4 ? 48.855 18.287 102.821 1.00 18.00 ? 4 MET L CG 1 ATOM 3105 S SD . MET B 2 4 ? 48.344 17.023 103.995 1.00 14.48 ? 4 MET L SD 1 ATOM 3106 C CE . MET B 2 4 ? 46.839 17.802 104.486 1.00 13.10 ? 4 MET L CE 1 ATOM 3107 N N . THR B 2 5 ? 45.632 16.985 99.667 1.00 21.55 ? 5 THR L N 1 ATOM 3108 C CA . THR B 2 5 ? 44.836 17.021 98.460 1.00 22.93 ? 5 THR L CA 1 ATOM 3109 C C . THR B 2 5 ? 43.578 17.773 98.815 1.00 25.17 ? 5 THR L C 1 ATOM 3110 O O . THR B 2 5 ? 42.997 17.511 99.866 1.00 25.50 ? 5 THR L O 1 ATOM 3111 C CB . THR B 2 5 ? 44.506 15.538 97.958 1.00 25.27 ? 5 THR L CB 1 ATOM 3112 O OG1 . THR B 2 5 ? 45.196 14.506 98.704 1.00 26.27 ? 5 THR L OG1 1 ATOM 3113 C CG2 . THR B 2 5 ? 44.977 15.406 96.510 1.00 24.51 ? 5 THR L CG2 1 ATOM 3114 N N . GLN B 2 6 ? 43.136 18.742 98.030 1.00 26.58 ? 6 GLN L N 1 ATOM 3115 C CA . GLN B 2 6 ? 41.890 19.423 98.343 1.00 25.95 ? 6 GLN L CA 1 ATOM 3116 C C . GLN B 2 6 ? 40.937 19.200 97.198 1.00 29.83 ? 6 GLN L C 1 ATOM 3117 O O . GLN B 2 6 ? 41.392 19.285 96.055 1.00 32.34 ? 6 GLN L O 1 ATOM 3118 C CB . GLN B 2 6 ? 42.119 20.906 98.504 1.00 24.35 ? 6 GLN L CB 1 ATOM 3119 C CG . GLN B 2 6 ? 42.707 21.249 99.850 1.00 22.08 ? 6 GLN L CG 1 ATOM 3120 C CD . GLN B 2 6 ? 43.018 22.724 100.003 1.00 23.28 ? 6 GLN L CD 1 ATOM 3121 O OE1 . GLN B 2 6 ? 44.164 23.098 100.260 1.00 22.70 ? 6 GLN L OE1 1 ATOM 3122 N NE2 . GLN B 2 6 ? 42.098 23.658 99.841 1.00 24.54 ? 6 GLN L NE2 1 ATOM 3123 N N . SER B 2 7 ? 39.668 18.855 97.418 1.00 32.60 ? 7 SER L N 1 ATOM 3124 C CA . SER B 2 7 ? 38.681 18.809 96.324 1.00 33.88 ? 7 SER L CA 1 ATOM 3125 C C . SER B 2 7 ? 37.284 19.140 96.898 1.00 34.31 ? 7 SER L C 1 ATOM 3126 O O . SER B 2 7 ? 36.960 18.737 98.038 1.00 36.70 ? 7 SER L O 1 ATOM 3127 C CB . SER B 2 7 ? 38.661 17.423 95.637 1.00 33.95 ? 7 SER L CB 1 ATOM 3128 O OG . SER B 2 7 ? 38.562 16.298 96.507 1.00 36.59 ? 7 SER L OG 1 ATOM 3129 N N . PRO B 2 8 ? 36.428 19.918 96.214 1.00 33.27 ? 8 PRO L N 1 ATOM 3130 C CA . PRO B 2 8 ? 36.762 20.666 95.006 1.00 31.80 ? 8 PRO L CA 1 ATOM 3131 C C . PRO B 2 8 ? 37.705 21.869 95.201 1.00 31.37 ? 8 PRO L C 1 ATOM 3132 O O . PRO B 2 8 ? 38.130 22.221 96.301 1.00 30.25 ? 8 PRO L O 1 ATOM 3133 C CB . PRO B 2 8 ? 35.369 21.039 94.453 1.00 31.86 ? 8 PRO L CB 1 ATOM 3134 C CG . PRO B 2 8 ? 34.380 20.120 95.138 1.00 31.64 ? 8 PRO L CG 1 ATOM 3135 C CD . PRO B 2 8 ? 34.994 20.005 96.519 1.00 32.12 ? 8 PRO L CD 1 ATOM 3136 N N . LYS B 2 9 ? 38.037 22.516 94.095 1.00 32.39 ? 9 LYS L N 1 ATOM 3137 C CA . LYS B 2 9 ? 38.861 23.707 94.108 1.00 35.53 ? 9 LYS L CA 1 ATOM 3138 C C . LYS B 2 9 ? 38.085 25.025 94.035 1.00 34.09 ? 9 LYS L C 1 ATOM 3139 O O . LYS B 2 9 ? 38.684 26.089 94.103 1.00 33.61 ? 9 LYS L O 1 ATOM 3140 C CB . LYS B 2 9 ? 39.870 23.635 92.950 1.00 38.48 ? 9 LYS L CB 1 ATOM 3141 C CG . LYS B 2 9 ? 39.394 23.643 91.479 1.00 42.24 ? 9 LYS L CG 1 ATOM 3142 C CD . LYS B 2 9 ? 40.582 23.674 90.479 1.00 45.17 ? 9 LYS L CD 1 ATOM 3143 C CE . LYS B 2 9 ? 41.433 24.988 90.588 1.00 47.54 ? 9 LYS L CE 1 ATOM 3144 N NZ . LYS B 2 9 ? 42.656 25.044 89.787 1.00 51.02 ? 9 LYS L NZ 1 ATOM 3145 N N . PHE B 2 10 ? 36.761 25.040 93.928 1.00 33.86 ? 10 PHE L N 1 ATOM 3146 C CA . PHE B 2 10 ? 35.966 26.257 93.879 1.00 34.93 ? 10 PHE L CA 1 ATOM 3147 C C . PHE B 2 10 ? 34.730 25.898 94.690 1.00 33.07 ? 10 PHE L C 1 ATOM 3148 O O . PHE B 2 10 ? 34.246 24.769 94.599 1.00 31.67 ? 10 PHE L O 1 ATOM 3149 C CB . PHE B 2 10 ? 35.631 26.582 92.424 1.00 37.33 ? 10 PHE L CB 1 ATOM 3150 C CG . PHE B 2 10 ? 34.566 27.659 92.182 1.00 40.98 ? 10 PHE L CG 1 ATOM 3151 C CD1 . PHE B 2 10 ? 34.924 29.001 92.113 1.00 42.25 ? 10 PHE L CD1 1 ATOM 3152 C CD2 . PHE B 2 10 ? 33.213 27.308 92.014 1.00 42.72 ? 10 PHE L CD2 1 ATOM 3153 C CE1 . PHE B 2 10 ? 33.948 29.965 91.848 1.00 43.63 ? 10 PHE L CE1 1 ATOM 3154 C CE2 . PHE B 2 10 ? 32.243 28.279 91.742 1.00 44.13 ? 10 PHE L CE2 1 ATOM 3155 C CZ . PHE B 2 10 ? 32.612 29.614 91.673 1.00 44.99 ? 10 PHE L CZ 1 ATOM 3156 N N . MET B 2 11 ? 34.207 26.803 95.506 1.00 31.72 ? 11 MET L N 1 ATOM 3157 C CA . MET B 2 11 ? 33.084 26.549 96.395 1.00 29.95 ? 11 MET L CA 1 ATOM 3158 C C . MET B 2 11 ? 32.149 27.737 96.492 1.00 29.25 ? 11 MET L C 1 ATOM 3159 O O . MET B 2 11 ? 32.642 28.861 96.496 1.00 28.21 ? 11 MET L O 1 ATOM 3160 C CB . MET B 2 11 ? 33.632 26.257 97.729 1.00 29.76 ? 11 MET L CB 1 ATOM 3161 C CG . MET B 2 11 ? 33.901 24.813 97.776 1.00 30.15 ? 11 MET L CG 1 ATOM 3162 S SD . MET B 2 11 ? 32.701 24.232 98.960 1.00 32.25 ? 11 MET L SD 1 ATOM 3163 C CE . MET B 2 11 ? 33.842 23.019 99.540 1.00 33.06 ? 11 MET L CE 1 ATOM 3164 N N . SER B 2 12 ? 30.835 27.585 96.585 1.00 31.34 ? 12 SER L N 1 ATOM 3165 C CA . SER B 2 12 ? 29.964 28.746 96.662 1.00 31.49 ? 12 SER L CA 1 ATOM 3166 C C . SER B 2 12 ? 28.931 28.537 97.735 1.00 29.95 ? 12 SER L C 1 ATOM 3167 O O . SER B 2 12 ? 28.251 27.512 97.776 1.00 30.47 ? 12 SER L O 1 ATOM 3168 C CB . SER B 2 12 ? 29.244 29.003 95.335 1.00 32.15 ? 12 SER L CB 1 ATOM 3169 O OG . SER B 2 12 ? 28.687 27.837 94.724 1.00 34.58 ? 12 SER L OG 1 ATOM 3170 N N . THR B 2 13 ? 28.871 29.531 98.593 1.00 28.55 ? 13 THR L N 1 ATOM 3171 C CA . THR B 2 13 ? 27.997 29.582 99.739 1.00 24.90 ? 13 THR L CA 1 ATOM 3172 C C . THR B 2 13 ? 27.341 30.950 99.660 1.00 24.72 ? 13 THR L C 1 ATOM 3173 O O . THR B 2 13 ? 27.797 31.829 98.928 1.00 25.59 ? 13 THR L O 1 ATOM 3174 C CB . THR B 2 13 ? 28.919 29.375 100.975 1.00 25.08 ? 13 THR L CB 1 ATOM 3175 O OG1 . THR B 2 13 ? 29.095 27.964 101.080 1.00 24.77 ? 13 THR L OG1 1 ATOM 3176 C CG2 . THR B 2 13 ? 28.374 29.898 102.287 1.00 25.35 ? 13 THR L CG2 1 ATOM 3177 N N . SER B 2 14 ? 26.220 31.126 100.339 1.00 21.69 ? 14 SER L N 1 ATOM 3178 C CA . SER B 2 14 ? 25.593 32.417 100.435 1.00 20.19 ? 14 SER L CA 1 ATOM 3179 C C . SER B 2 14 ? 26.116 33.192 101.628 1.00 19.88 ? 14 SER L C 1 ATOM 3180 O O . SER B 2 14 ? 26.917 32.671 102.422 1.00 19.47 ? 14 SER L O 1 ATOM 3181 C CB . SER B 2 14 ? 24.121 32.176 100.548 1.00 22.86 ? 14 SER L CB 1 ATOM 3182 O OG . SER B 2 14 ? 23.586 31.863 99.278 1.00 24.16 ? 14 SER L OG 1 ATOM 3183 N N . VAL B 2 15 ? 25.641 34.429 101.794 1.00 18.30 ? 15 VAL L N 1 ATOM 3184 C CA . VAL B 2 15 ? 26.025 35.211 102.949 1.00 18.37 ? 15 VAL L CA 1 ATOM 3185 C C . VAL B 2 15 ? 25.303 34.676 104.158 1.00 20.08 ? 15 VAL L C 1 ATOM 3186 O O . VAL B 2 15 ? 24.180 34.187 104.077 1.00 19.52 ? 15 VAL L O 1 ATOM 3187 C CB . VAL B 2 15 ? 25.686 36.679 102.692 1.00 19.22 ? 15 VAL L CB 1 ATOM 3188 C CG1 . VAL B 2 15 ? 25.012 37.454 103.821 1.00 17.41 ? 15 VAL L CG1 1 ATOM 3189 C CG2 . VAL B 2 15 ? 27.048 37.302 102.518 1.00 19.40 ? 15 VAL L CG2 1 ATOM 3190 N N . GLY B 2 16 ? 25.980 34.681 105.286 1.00 22.71 ? 16 GLY L N 1 ATOM 3191 C CA . GLY B 2 16 ? 25.358 34.223 106.517 1.00 24.97 ? 16 GLY L CA 1 ATOM 3192 C C . GLY B 2 16 ? 25.222 32.717 106.619 1.00 26.18 ? 16 GLY L C 1 ATOM 3193 O O . GLY B 2 16 ? 24.833 32.198 107.660 1.00 28.16 ? 16 GLY L O 1 ATOM 3194 N N . ASP B 2 17 ? 25.676 32.007 105.609 1.00 26.98 ? 17 ASP L N 1 ATOM 3195 C CA . ASP B 2 17 ? 25.509 30.583 105.565 1.00 28.78 ? 17 ASP L CA 1 ATOM 3196 C C . ASP B 2 17 ? 26.791 29.890 106.021 1.00 29.12 ? 17 ASP L C 1 ATOM 3197 O O . ASP B 2 17 ? 27.548 30.478 106.806 1.00 30.28 ? 17 ASP L O 1 ATOM 3198 C CB . ASP B 2 17 ? 25.111 30.263 104.135 1.00 31.41 ? 17 ASP L CB 1 ATOM 3199 C CG . ASP B 2 17 ? 23.653 29.810 103.981 1.00 34.90 ? 17 ASP L CG 1 ATOM 3200 O OD1 . ASP B 2 17 ? 23.395 28.624 104.259 1.00 36.72 ? 17 ASP L OD1 1 ATOM 3201 O OD2 . ASP B 2 17 ? 22.798 30.618 103.582 1.00 36.57 ? 17 ASP L OD2 1 ATOM 3202 N N . ARG B 2 18 ? 27.086 28.686 105.535 1.00 29.71 ? 18 ARG L N 1 ATOM 3203 C CA . ARG B 2 18 ? 28.230 27.915 105.955 1.00 30.84 ? 18 ARG L CA 1 ATOM 3204 C C . ARG B 2 18 ? 28.978 27.270 104.805 1.00 27.43 ? 18 ARG L C 1 ATOM 3205 O O . ARG B 2 18 ? 28.360 26.967 103.778 1.00 28.13 ? 18 ARG L O 1 ATOM 3206 C CB . ARG B 2 18 ? 27.785 26.818 106.873 1.00 37.02 ? 18 ARG L CB 1 ATOM 3207 C CG . ARG B 2 18 ? 28.041 27.120 108.308 1.00 44.19 ? 18 ARG L CG 1 ATOM 3208 C CD . ARG B 2 18 ? 28.098 25.787 109.022 1.00 50.42 ? 18 ARG L CD 1 ATOM 3209 N NE . ARG B 2 18 ? 28.251 25.903 110.466 1.00 57.36 ? 18 ARG L NE 1 ATOM 3210 C CZ . ARG B 2 18 ? 27.329 26.467 111.275 1.00 61.45 ? 18 ARG L CZ 1 ATOM 3211 N NH1 . ARG B 2 18 ? 26.252 27.112 110.808 1.00 63.78 ? 18 ARG L NH1 1 ATOM 3212 N NH2 . ARG B 2 18 ? 27.515 26.420 112.602 1.00 63.85 ? 18 ARG L NH2 1 ATOM 3213 N N . VAL B 2 19 ? 30.275 27.023 104.894 1.00 23.46 ? 19 VAL L N 1 ATOM 3214 C CA . VAL B 2 19 ? 30.934 26.212 103.883 1.00 18.88 ? 19 VAL L CA 1 ATOM 3215 C C . VAL B 2 19 ? 31.879 25.266 104.627 1.00 17.88 ? 19 VAL L C 1 ATOM 3216 O O . VAL B 2 19 ? 32.331 25.524 105.755 1.00 17.21 ? 19 VAL L O 1 ATOM 3217 C CB . VAL B 2 19 ? 31.661 27.168 102.930 1.00 17.73 ? 19 VAL L CB 1 ATOM 3218 C CG1 . VAL B 2 19 ? 32.863 27.759 103.644 1.00 18.41 ? 19 VAL L CG1 1 ATOM 3219 C CG2 . VAL B 2 19 ? 32.093 26.451 101.681 1.00 18.01 ? 19 VAL L CG2 1 ATOM 3220 N N . THR B 2 20 ? 32.092 24.111 104.055 1.00 17.14 ? 20 THR L N 1 ATOM 3221 C CA . THR B 2 20 ? 33.047 23.204 104.615 1.00 15.75 ? 20 THR L CA 1 ATOM 3222 C C . THR B 2 20 ? 34.027 22.816 103.496 1.00 15.43 ? 20 THR L C 1 ATOM 3223 O O . THR B 2 20 ? 33.660 22.328 102.409 1.00 17.34 ? 20 THR L O 1 ATOM 3224 C CB . THR B 2 20 ? 32.155 22.109 105.224 1.00 14.87 ? 20 THR L CB 1 ATOM 3225 O OG1 . THR B 2 20 ? 32.647 22.043 106.531 1.00 16.16 ? 20 THR L OG1 1 ATOM 3226 C CG2 . THR B 2 20 ? 32.190 20.723 104.629 1.00 15.11 ? 20 THR L CG2 1 ATOM 3227 N N . ILE B 2 21 ? 35.297 23.133 103.709 1.00 15.70 ? 21 ILE L N 1 ATOM 3228 C CA . ILE B 2 21 ? 36.332 22.894 102.733 1.00 15.56 ? 21 ILE L CA 1 ATOM 3229 C C . ILE B 2 21 ? 37.098 21.653 103.124 1.00 16.99 ? 21 ILE L C 1 ATOM 3230 O O . ILE B 2 21 ? 37.815 21.747 104.115 1.00 20.40 ? 21 ILE L O 1 ATOM 3231 C CB . ILE B 2 21 ? 37.137 24.176 102.757 1.00 14.89 ? 21 ILE L CB 1 ATOM 3232 C CG1 . ILE B 2 21 ? 36.275 25.215 102.074 1.00 13.59 ? 21 ILE L CG1 1 ATOM 3233 C CG2 . ILE B 2 21 ? 38.519 24.017 102.144 1.00 14.92 ? 21 ILE L CG2 1 ATOM 3234 C CD1 . ILE B 2 21 ? 36.236 26.534 102.845 1.00 15.29 ? 21 ILE L CD1 1 ATOM 3235 N N . THR B 2 22 ? 37.007 20.515 102.451 1.00 19.22 ? 22 THR L N 1 ATOM 3236 C CA . THR B 2 22 ? 37.745 19.320 102.825 1.00 21.47 ? 22 THR L CA 1 ATOM 3237 C C . THR B 2 22 ? 39.185 19.386 102.340 1.00 20.62 ? 22 THR L C 1 ATOM 3238 O O . THR B 2 22 ? 39.436 19.797 101.201 1.00 22.45 ? 22 THR L O 1 ATOM 3239 C CB . THR B 2 22 ? 37.014 18.079 102.221 1.00 22.52 ? 22 THR L CB 1 ATOM 3240 O OG1 . THR B 2 22 ? 35.650 18.167 102.648 1.00 22.91 ? 22 THR L OG1 1 ATOM 3241 C CG2 . THR B 2 22 ? 37.598 16.737 102.675 1.00 23.16 ? 22 THR L CG2 1 ATOM 3242 N N . CYS B 2 23 ? 40.106 18.930 103.200 1.00 18.52 ? 23 CYS L N 1 ATOM 3243 C CA . CYS B 2 23 ? 41.523 18.744 102.911 1.00 15.77 ? 23 CYS L CA 1 ATOM 3244 C C . CYS B 2 23 ? 41.798 17.310 103.357 1.00 17.25 ? 23 CYS L C 1 ATOM 3245 O O . CYS B 2 23 ? 41.116 16.780 104.262 1.00 14.91 ? 23 CYS L O 1 ATOM 3246 C CB . CYS B 2 23 ? 42.359 19.706 103.709 1.00 12.56 ? 23 CYS L CB 1 ATOM 3247 S SG . CYS B 2 23 ? 44.094 19.368 103.826 1.00 8.29 ? 23 CYS L SG 1 ATOM 3248 N N . LYS B 2 24 ? 42.844 16.698 102.776 1.00 18.45 ? 24 LYS L N 1 ATOM 3249 C CA . LYS B 2 24 ? 43.142 15.280 102.934 1.00 20.05 ? 24 LYS L CA 1 ATOM 3250 C C . LYS B 2 24 ? 44.604 15.014 102.704 1.00 19.14 ? 24 LYS L C 1 ATOM 3251 O O . LYS B 2 24 ? 45.142 15.266 101.637 1.00 18.07 ? 24 LYS L O 1 ATOM 3252 C CB . LYS B 2 24 ? 42.301 14.431 101.934 1.00 24.11 ? 24 LYS L CB 1 ATOM 3253 C CG . LYS B 2 24 ? 42.871 13.055 101.524 1.00 28.86 ? 24 LYS L CG 1 ATOM 3254 C CD . LYS B 2 24 ? 41.903 11.927 101.083 1.00 33.15 ? 24 LYS L CD 1 ATOM 3255 C CE . LYS B 2 24 ? 42.629 10.918 100.135 1.00 34.38 ? 24 LYS L CE 1 ATOM 3256 N NZ . LYS B 2 24 ? 43.807 10.256 100.697 1.00 35.74 ? 24 LYS L NZ 1 ATOM 3257 N N . ALA B 2 25 ? 45.245 14.542 103.754 1.00 20.95 ? 25 ALA L N 1 ATOM 3258 C CA . ALA B 2 25 ? 46.644 14.129 103.707 1.00 22.91 ? 25 ALA L CA 1 ATOM 3259 C C . ALA B 2 25 ? 46.675 12.681 103.257 1.00 22.62 ? 25 ALA L C 1 ATOM 3260 O O . ALA B 2 25 ? 45.719 11.925 103.430 1.00 20.02 ? 25 ALA L O 1 ATOM 3261 C CB . ALA B 2 25 ? 47.299 14.180 105.074 1.00 21.07 ? 25 ALA L CB 1 ATOM 3262 N N . SER B 2 26 ? 47.788 12.279 102.683 1.00 24.17 ? 26 SER L N 1 ATOM 3263 C CA . SER B 2 26 ? 47.980 10.909 102.263 1.00 25.07 ? 26 SER L CA 1 ATOM 3264 C C . SER B 2 26 ? 48.718 10.002 103.264 1.00 25.80 ? 26 SER L C 1 ATOM 3265 O O . SER B 2 26 ? 49.622 9.247 102.876 1.00 27.23 ? 26 SER L O 1 ATOM 3266 C CB . SER B 2 26 ? 48.694 10.999 100.928 1.00 25.74 ? 26 SER L CB 1 ATOM 3267 O OG . SER B 2 26 ? 50.034 11.496 101.039 1.00 29.17 ? 26 SER L OG 1 ATOM 3268 N N . GLN B 2 27 ? 48.462 10.137 104.576 1.00 29.65 ? 27 GLN L N 1 ATOM 3269 C CA . GLN B 2 27 ? 48.929 9.262 105.657 1.00 31.40 ? 27 GLN L CA 1 ATOM 3270 C C . GLN B 2 27 ? 48.566 9.920 106.965 1.00 30.82 ? 27 GLN L C 1 ATOM 3271 O O . GLN B 2 27 ? 48.310 11.125 106.918 1.00 33.29 ? 27 GLN L O 1 ATOM 3272 C CB . GLN B 2 27 ? 50.417 9.045 105.668 1.00 32.77 ? 27 GLN L CB 1 ATOM 3273 C CG . GLN B 2 27 ? 51.351 10.164 105.963 1.00 35.33 ? 27 GLN L CG 1 ATOM 3274 C CD . GLN B 2 27 ? 52.640 9.458 106.318 1.00 38.23 ? 27 GLN L CD 1 ATOM 3275 O OE1 . GLN B 2 27 ? 52.967 9.233 107.491 1.00 39.46 ? 27 GLN L OE1 1 ATOM 3276 N NE2 . GLN B 2 27 ? 53.369 9.022 105.286 1.00 39.95 ? 27 GLN L NE2 1 ATOM 3277 N N . ASP B 2 28 ? 48.524 9.241 108.120 1.00 29.34 ? 28 ASP L N 1 ATOM 3278 C CA . ASP B 2 28 ? 47.991 9.878 109.319 1.00 29.82 ? 28 ASP L CA 1 ATOM 3279 C C . ASP B 2 28 ? 48.979 10.944 109.774 1.00 28.92 ? 28 ASP L C 1 ATOM 3280 O O . ASP B 2 28 ? 50.155 10.722 110.060 1.00 29.64 ? 28 ASP L O 1 ATOM 3281 C CB . ASP B 2 28 ? 47.763 8.807 110.386 1.00 32.92 ? 28 ASP L CB 1 ATOM 3282 C CG . ASP B 2 28 ? 47.155 9.251 111.726 1.00 35.52 ? 28 ASP L CG 1 ATOM 3283 O OD1 . ASP B 2 28 ? 46.808 10.418 111.941 1.00 37.60 ? 28 ASP L OD1 1 ATOM 3284 O OD2 . ASP B 2 28 ? 47.018 8.383 112.587 1.00 35.86 ? 28 ASP L OD2 1 ATOM 3285 N N . VAL B 2 29 ? 48.471 12.150 109.790 1.00 26.43 ? 29 VAL L N 1 ATOM 3286 C CA . VAL B 2 29 ? 49.328 13.253 110.077 1.00 25.28 ? 29 VAL L CA 1 ATOM 3287 C C . VAL B 2 29 ? 49.009 13.876 111.433 1.00 25.84 ? 29 VAL L C 1 ATOM 3288 O O . VAL B 2 29 ? 49.392 14.990 111.777 1.00 28.40 ? 29 VAL L O 1 ATOM 3289 C CB . VAL B 2 29 ? 49.140 14.066 108.800 1.00 24.98 ? 29 VAL L CB 1 ATOM 3290 C CG1 . VAL B 2 29 ? 47.800 14.713 108.640 1.00 26.38 ? 29 VAL L CG1 1 ATOM 3291 C CG2 . VAL B 2 29 ? 50.199 15.063 108.833 1.00 26.84 ? 29 VAL L CG2 1 ATOM 3292 N N . SER B 2 30 ? 48.218 13.171 112.235 1.00 25.32 ? 30 SER L N 1 ATOM 3293 C CA . SER B 2 30 ? 47.991 13.464 113.641 1.00 23.42 ? 30 SER L CA 1 ATOM 3294 C C . SER B 2 30 ? 47.542 14.827 114.110 1.00 22.94 ? 30 SER L C 1 ATOM 3295 O O . SER B 2 30 ? 47.922 15.390 115.160 1.00 25.51 ? 30 SER L O 1 ATOM 3296 C CB . SER B 2 30 ? 49.247 13.081 114.417 1.00 24.36 ? 30 SER L CB 1 ATOM 3297 O OG . SER B 2 30 ? 49.168 11.708 114.770 1.00 24.15 ? 30 SER L OG 1 ATOM 3298 N N . THR B 2 31 ? 46.659 15.301 113.248 1.00 22.05 ? 31 THR L N 1 ATOM 3299 C CA . THR B 2 31 ? 45.973 16.571 113.427 1.00 17.47 ? 31 THR L CA 1 ATOM 3300 C C . THR B 2 31 ? 46.896 17.770 113.164 1.00 15.19 ? 31 THR L C 1 ATOM 3301 O O . THR B 2 31 ? 46.517 18.943 113.167 1.00 13.73 ? 31 THR L O 1 ATOM 3302 C CB . THR B 2 31 ? 45.359 16.387 114.838 1.00 17.40 ? 31 THR L CB 1 ATOM 3303 O OG1 . THR B 2 31 ? 44.429 15.329 114.566 1.00 18.36 ? 31 THR L OG1 1 ATOM 3304 C CG2 . THR B 2 31 ? 44.748 17.570 115.522 1.00 18.46 ? 31 THR L CG2 1 ATOM 3305 N N . ALA B 2 32 ? 48.097 17.475 112.690 1.00 12.77 ? 32 ALA L N 1 ATOM 3306 C CA . ALA B 2 32 ? 49.080 18.468 112.412 1.00 11.46 ? 32 ALA L CA 1 ATOM 3307 C C . ALA B 2 32 ? 48.766 18.992 111.008 1.00 9.58 ? 32 ALA L C 1 ATOM 3308 O O . ALA B 2 32 ? 49.453 18.716 110.010 1.00 8.84 ? 32 ALA L O 1 ATOM 3309 C CB . ALA B 2 32 ? 50.410 17.743 112.531 1.00 10.55 ? 32 ALA L CB 1 ATOM 3310 N N . VAL B 2 33 ? 47.692 19.776 110.930 1.00 7.27 ? 33 VAL L N 1 ATOM 3311 C CA . VAL B 2 33 ? 47.187 20.348 109.700 1.00 6.18 ? 33 VAL L CA 1 ATOM 3312 C C . VAL B 2 33 ? 47.032 21.798 110.030 1.00 6.90 ? 33 VAL L C 1 ATOM 3313 O O . VAL B 2 33 ? 46.482 22.068 111.102 1.00 8.01 ? 33 VAL L O 1 ATOM 3314 C CB . VAL B 2 33 ? 45.867 19.683 109.384 1.00 4.95 ? 33 VAL L CB 1 ATOM 3315 C CG1 . VAL B 2 33 ? 44.773 20.521 108.753 1.00 5.72 ? 33 VAL L CG1 1 ATOM 3316 C CG2 . VAL B 2 33 ? 46.281 18.700 108.357 1.00 3.70 ? 33 VAL L CG2 1 ATOM 3317 N N . VAL B 2 34 ? 47.571 22.718 109.233 1.00 6.62 ? 34 VAL L N 1 ATOM 3318 C CA . VAL B 2 34 ? 47.395 24.167 109.431 1.00 7.30 ? 34 VAL L CA 1 ATOM 3319 C C . VAL B 2 34 ? 46.436 24.601 108.326 1.00 8.75 ? 34 VAL L C 1 ATOM 3320 O O . VAL B 2 34 ? 46.476 23.944 107.272 1.00 9.53 ? 34 VAL L O 1 ATOM 3321 C CB . VAL B 2 34 ? 48.636 24.994 109.193 1.00 7.07 ? 34 VAL L CB 1 ATOM 3322 C CG1 . VAL B 2 34 ? 48.425 26.463 109.422 1.00 7.72 ? 34 VAL L CG1 1 ATOM 3323 C CG2 . VAL B 2 34 ? 49.609 24.636 110.215 1.00 7.86 ? 34 VAL L CG2 1 ATOM 3324 N N . TRP B 2 35 ? 45.589 25.630 108.507 1.00 7.84 ? 35 TRP L N 1 ATOM 3325 C CA . TRP B 2 35 ? 44.741 26.152 107.454 1.00 4.46 ? 35 TRP L CA 1 ATOM 3326 C C . TRP B 2 35 ? 45.205 27.598 107.254 1.00 5.09 ? 35 TRP L C 1 ATOM 3327 O O . TRP B 2 35 ? 45.300 28.346 108.228 1.00 6.12 ? 35 TRP L O 1 ATOM 3328 C CB . TRP B 2 35 ? 43.259 26.090 107.891 1.00 2.24 ? 35 TRP L CB 1 ATOM 3329 C CG . TRP B 2 35 ? 42.538 24.753 107.693 1.00 6.22 ? 35 TRP L CG 1 ATOM 3330 C CD1 . TRP B 2 35 ? 42.338 23.894 108.741 1.00 6.14 ? 35 TRP L CD1 1 ATOM 3331 C CD2 . TRP B 2 35 ? 42.035 24.213 106.515 1.00 6.20 ? 35 TRP L CD2 1 ATOM 3332 N NE1 . TRP B 2 35 ? 41.722 22.836 108.250 1.00 4.84 ? 35 TRP L NE1 1 ATOM 3333 C CE2 . TRP B 2 35 ? 41.534 23.000 106.935 1.00 3.37 ? 35 TRP L CE2 1 ATOM 3334 C CE3 . TRP B 2 35 ? 41.940 24.564 105.182 1.00 5.05 ? 35 TRP L CE3 1 ATOM 3335 C CZ2 . TRP B 2 35 ? 40.944 22.144 106.071 1.00 2.00 ? 35 TRP L CZ2 1 ATOM 3336 C CZ3 . TRP B 2 35 ? 41.345 23.699 104.304 1.00 3.37 ? 35 TRP L CZ3 1 ATOM 3337 C CH2 . TRP B 2 35 ? 40.857 22.510 104.755 1.00 2.00 ? 35 TRP L CH2 1 ATOM 3338 N N . TYR B 2 36 ? 45.627 28.057 106.086 1.00 5.91 ? 36 TYR L N 1 ATOM 3339 C CA . TYR B 2 36 ? 45.887 29.488 105.846 1.00 7.22 ? 36 TYR L CA 1 ATOM 3340 C C . TYR B 2 36 ? 44.754 29.987 104.925 1.00 8.29 ? 36 TYR L C 1 ATOM 3341 O O . TYR B 2 36 ? 44.024 29.210 104.264 1.00 8.73 ? 36 TYR L O 1 ATOM 3342 C CB . TYR B 2 36 ? 47.156 29.797 105.092 1.00 5.67 ? 36 TYR L CB 1 ATOM 3343 C CG . TYR B 2 36 ? 48.394 29.215 105.701 1.00 5.82 ? 36 TYR L CG 1 ATOM 3344 C CD1 . TYR B 2 36 ? 48.687 27.859 105.604 1.00 5.11 ? 36 TYR L CD1 1 ATOM 3345 C CD2 . TYR B 2 36 ? 49.233 30.070 106.356 1.00 6.52 ? 36 TYR L CD2 1 ATOM 3346 C CE1 . TYR B 2 36 ? 49.837 27.355 106.179 1.00 6.50 ? 36 TYR L CE1 1 ATOM 3347 C CE2 . TYR B 2 36 ? 50.370 29.552 106.924 1.00 7.73 ? 36 TYR L CE2 1 ATOM 3348 C CZ . TYR B 2 36 ? 50.675 28.208 106.851 1.00 7.43 ? 36 TYR L CZ 1 ATOM 3349 O OH . TYR B 2 36 ? 51.805 27.762 107.527 1.00 9.48 ? 36 TYR L OH 1 ATOM 3350 N N . GLN B 2 37 ? 44.592 31.322 104.923 1.00 9.91 ? 37 GLN L N 1 ATOM 3351 C CA . GLN B 2 37 ? 43.609 32.024 104.096 1.00 9.77 ? 37 GLN L CA 1 ATOM 3352 C C . GLN B 2 37 ? 44.331 33.059 103.239 1.00 12.62 ? 37 GLN L C 1 ATOM 3353 O O . GLN B 2 37 ? 45.097 33.817 103.832 1.00 16.95 ? 37 GLN L O 1 ATOM 3354 C CB . GLN B 2 37 ? 42.629 32.752 104.975 1.00 8.86 ? 37 GLN L CB 1 ATOM 3355 C CG . GLN B 2 37 ? 41.686 33.666 104.178 1.00 10.15 ? 37 GLN L CG 1 ATOM 3356 C CD . GLN B 2 37 ? 40.976 34.695 105.031 1.00 10.40 ? 37 GLN L CD 1 ATOM 3357 O OE1 . GLN B 2 37 ? 41.590 35.698 105.429 1.00 9.11 ? 37 GLN L OE1 1 ATOM 3358 N NE2 . GLN B 2 37 ? 39.696 34.436 105.315 1.00 10.19 ? 37 GLN L NE2 1 ATOM 3359 N N . GLN B 2 38 ? 44.152 33.211 101.932 1.00 14.68 ? 38 GLN L N 1 ATOM 3360 C CA . GLN B 2 38 ? 44.858 34.228 101.198 1.00 16.06 ? 38 GLN L CA 1 ATOM 3361 C C . GLN B 2 38 ? 43.802 35.082 100.501 1.00 18.09 ? 38 GLN L C 1 ATOM 3362 O O . GLN B 2 38 ? 43.147 34.729 99.501 1.00 17.05 ? 38 GLN L O 1 ATOM 3363 C CB . GLN B 2 38 ? 45.775 33.565 100.223 1.00 15.68 ? 38 GLN L CB 1 ATOM 3364 C CG . GLN B 2 38 ? 46.430 34.615 99.356 1.00 15.95 ? 38 GLN L CG 1 ATOM 3365 C CD . GLN B 2 38 ? 47.470 33.991 98.478 1.00 15.49 ? 38 GLN L CD 1 ATOM 3366 O OE1 . GLN B 2 38 ? 47.334 32.921 97.901 1.00 15.07 ? 38 GLN L OE1 1 ATOM 3367 N NE2 . GLN B 2 38 ? 48.546 34.712 98.316 1.00 17.95 ? 38 GLN L NE2 1 ATOM 3368 N N . LYS B 2 39 ? 43.530 36.204 101.170 1.00 22.26 ? 39 LYS L N 1 ATOM 3369 C CA . LYS B 2 39 ? 42.555 37.169 100.680 1.00 23.65 ? 39 LYS L CA 1 ATOM 3370 C C . LYS B 2 39 ? 43.080 37.687 99.333 1.00 25.14 ? 39 LYS L C 1 ATOM 3371 O O . LYS B 2 39 ? 44.287 37.967 99.191 1.00 23.98 ? 39 LYS L O 1 ATOM 3372 C CB . LYS B 2 39 ? 42.449 38.266 101.727 1.00 23.37 ? 39 LYS L CB 1 ATOM 3373 C CG . LYS B 2 39 ? 41.064 38.703 102.125 1.00 22.65 ? 39 LYS L CG 1 ATOM 3374 C CD . LYS B 2 39 ? 40.542 37.825 103.230 1.00 24.14 ? 39 LYS L CD 1 ATOM 3375 C CE . LYS B 2 39 ? 39.798 38.672 104.270 1.00 23.17 ? 39 LYS L CE 1 ATOM 3376 N NZ . LYS B 2 39 ? 39.075 37.819 105.203 1.00 23.98 ? 39 LYS L NZ 1 ATOM 3377 N N . PRO B 2 40 ? 42.198 37.774 98.314 1.00 26.76 ? 40 PRO L N 1 ATOM 3378 C CA . PRO B 2 40 ? 42.518 38.110 96.909 1.00 28.37 ? 40 PRO L CA 1 ATOM 3379 C C . PRO B 2 40 ? 43.565 39.202 96.784 1.00 28.56 ? 40 PRO L C 1 ATOM 3380 O O . PRO B 2 40 ? 43.349 40.353 97.187 1.00 26.94 ? 40 PRO L O 1 ATOM 3381 C CB . PRO B 2 40 ? 41.200 38.517 96.255 1.00 27.72 ? 40 PRO L CB 1 ATOM 3382 C CG . PRO B 2 40 ? 40.411 39.024 97.434 1.00 28.32 ? 40 PRO L CG 1 ATOM 3383 C CD . PRO B 2 40 ? 40.762 37.952 98.481 1.00 27.66 ? 40 PRO L CD 1 ATOM 3384 N N . GLY B 2 41 ? 44.745 38.661 96.446 1.00 28.55 ? 41 GLY L N 1 ATOM 3385 C CA . GLY B 2 41 ? 45.928 39.458 96.197 1.00 29.20 ? 41 GLY L CA 1 ATOM 3386 C C . GLY B 2 41 ? 46.518 40.036 97.478 1.00 28.35 ? 41 GLY L C 1 ATOM 3387 O O . GLY B 2 41 ? 46.750 41.247 97.604 1.00 29.44 ? 41 GLY L O 1 ATOM 3388 N N . GLN B 2 42 ? 46.721 39.139 98.449 1.00 27.20 ? 42 GLN L N 1 ATOM 3389 C CA . GLN B 2 42 ? 47.395 39.475 99.698 1.00 26.09 ? 42 GLN L CA 1 ATOM 3390 C C . GLN B 2 42 ? 48.222 38.285 100.120 1.00 23.13 ? 42 GLN L C 1 ATOM 3391 O O . GLN B 2 42 ? 48.258 37.300 99.379 1.00 21.42 ? 42 GLN L O 1 ATOM 3392 C CB . GLN B 2 42 ? 46.413 39.773 100.792 1.00 27.76 ? 42 GLN L CB 1 ATOM 3393 C CG . GLN B 2 42 ? 46.180 41.225 100.793 1.00 32.06 ? 42 GLN L CG 1 ATOM 3394 C CD . GLN B 2 42 ? 44.821 41.400 101.358 1.00 36.19 ? 42 GLN L CD 1 ATOM 3395 O OE1 . GLN B 2 42 ? 44.640 41.493 102.567 1.00 39.38 ? 42 GLN L OE1 1 ATOM 3396 N NE2 . GLN B 2 42 ? 43.823 41.406 100.482 1.00 37.74 ? 42 GLN L NE2 1 ATOM 3397 N N . SER B 2 43 ? 48.899 38.373 101.263 1.00 21.67 ? 43 SER L N 1 ATOM 3398 C CA . SER B 2 43 ? 49.634 37.266 101.851 1.00 19.12 ? 43 SER L CA 1 ATOM 3399 C C . SER B 2 43 ? 48.655 36.226 102.387 1.00 17.27 ? 43 SER L C 1 ATOM 3400 O O . SER B 2 43 ? 47.463 36.561 102.556 1.00 18.71 ? 43 SER L O 1 ATOM 3401 C CB . SER B 2 43 ? 50.486 37.851 102.964 1.00 20.15 ? 43 SER L CB 1 ATOM 3402 O OG . SER B 2 43 ? 51.413 38.830 102.481 1.00 23.38 ? 43 SER L OG 1 ATOM 3403 N N . PRO B 2 44 ? 49.059 34.969 102.641 1.00 12.72 ? 44 PRO L N 1 ATOM 3404 C CA . PRO B 2 44 ? 48.342 34.111 103.569 1.00 10.25 ? 44 PRO L CA 1 ATOM 3405 C C . PRO B 2 44 ? 48.420 34.635 105.014 1.00 13.05 ? 44 PRO L C 1 ATOM 3406 O O . PRO B 2 44 ? 49.362 35.354 105.391 1.00 13.64 ? 44 PRO L O 1 ATOM 3407 C CB . PRO B 2 44 ? 48.982 32.747 103.316 1.00 9.85 ? 44 PRO L CB 1 ATOM 3408 C CG . PRO B 2 44 ? 49.427 32.736 101.873 1.00 9.36 ? 44 PRO L CG 1 ATOM 3409 C CD . PRO B 2 44 ? 49.984 34.183 101.812 1.00 11.99 ? 44 PRO L CD 1 ATOM 3410 N N . LYS B 2 45 ? 47.340 34.334 105.768 1.00 12.51 ? 45 LYS L N 1 ATOM 3411 C CA . LYS B 2 45 ? 47.099 34.589 107.190 1.00 12.29 ? 45 LYS L CA 1 ATOM 3412 C C . LYS B 2 45 ? 46.848 33.183 107.746 1.00 13.18 ? 45 LYS L C 1 ATOM 3413 O O . LYS B 2 45 ? 46.023 32.405 107.229 1.00 10.76 ? 45 LYS L O 1 ATOM 3414 C CB . LYS B 2 45 ? 45.831 35.428 107.405 1.00 11.96 ? 45 LYS L CB 1 ATOM 3415 C CG . LYS B 2 45 ? 45.493 35.742 108.864 1.00 12.09 ? 45 LYS L CG 1 ATOM 3416 C CD . LYS B 2 45 ? 44.116 36.385 109.075 1.00 12.33 ? 45 LYS L CD 1 ATOM 3417 C CE . LYS B 2 45 ? 43.989 37.735 108.377 1.00 12.46 ? 45 LYS L CE 1 ATOM 3418 N NZ . LYS B 2 45 ? 42.759 38.419 108.732 1.00 12.65 ? 45 LYS L NZ 1 ATOM 3419 N N . LEU B 2 46 ? 47.655 32.798 108.738 1.00 12.50 ? 46 LEU L N 1 ATOM 3420 C CA . LEU B 2 46 ? 47.492 31.528 109.464 1.00 13.81 ? 46 LEU L CA 1 ATOM 3421 C C . LEU B 2 46 ? 46.256 31.664 110.345 1.00 14.02 ? 46 LEU L C 1 ATOM 3422 O O . LEU B 2 46 ? 46.227 32.378 111.341 1.00 14.81 ? 46 LEU L O 1 ATOM 3423 C CB . LEU B 2 46 ? 48.747 31.255 110.319 1.00 15.46 ? 46 LEU L CB 1 ATOM 3424 C CG . LEU B 2 46 ? 48.985 30.020 111.136 1.00 13.77 ? 46 LEU L CG 1 ATOM 3425 C CD1 . LEU B 2 46 ? 50.133 30.398 111.982 1.00 14.04 ? 46 LEU L CD1 1 ATOM 3426 C CD2 . LEU B 2 46 ? 47.923 29.650 112.146 1.00 16.06 ? 46 LEU L CD2 1 ATOM 3427 N N . LEU B 2 47 ? 45.264 30.910 109.950 1.00 12.98 ? 47 LEU L N 1 ATOM 3428 C CA . LEU B 2 47 ? 43.933 30.872 110.504 1.00 9.84 ? 47 LEU L CA 1 ATOM 3429 C C . LEU B 2 47 ? 43.803 29.919 111.682 1.00 9.84 ? 47 LEU L C 1 ATOM 3430 O O . LEU B 2 47 ? 43.344 30.260 112.761 1.00 9.10 ? 47 LEU L O 1 ATOM 3431 C CB . LEU B 2 47 ? 43.091 30.473 109.334 1.00 9.24 ? 47 LEU L CB 1 ATOM 3432 C CG . LEU B 2 47 ? 41.765 31.015 109.070 1.00 10.13 ? 47 LEU L CG 1 ATOM 3433 C CD1 . LEU B 2 47 ? 41.843 32.520 108.941 1.00 10.93 ? 47 LEU L CD1 1 ATOM 3434 C CD2 . LEU B 2 47 ? 41.257 30.366 107.813 1.00 8.05 ? 47 LEU L CD2 1 ATOM 3435 N N . ILE B 2 48 ? 44.242 28.685 111.550 1.00 9.21 ? 48 ILE L N 1 ATOM 3436 C CA . ILE B 2 48 ? 44.084 27.650 112.557 1.00 8.47 ? 48 ILE L CA 1 ATOM 3437 C C . ILE B 2 48 ? 45.361 26.757 112.495 1.00 8.73 ? 48 ILE L C 1 ATOM 3438 O O . ILE B 2 48 ? 46.008 26.654 111.430 1.00 7.89 ? 48 ILE L O 1 ATOM 3439 C CB . ILE B 2 48 ? 42.724 26.973 112.107 1.00 6.63 ? 48 ILE L CB 1 ATOM 3440 C CG1 . ILE B 2 48 ? 41.547 27.618 112.788 1.00 6.65 ? 48 ILE L CG1 1 ATOM 3441 C CG2 . ILE B 2 48 ? 42.818 25.461 112.315 1.00 6.00 ? 48 ILE L CG2 1 ATOM 3442 C CD1 . ILE B 2 48 ? 40.208 27.063 112.358 1.00 7.35 ? 48 ILE L CD1 1 ATOM 3443 N N . TYR B 2 49 ? 45.797 26.070 113.545 1.00 8.48 ? 49 TYR L N 1 ATOM 3444 C CA . TYR B 2 49 ? 46.875 25.078 113.465 1.00 8.42 ? 49 TYR L CA 1 ATOM 3445 C C . TYR B 2 49 ? 46.463 23.935 114.392 1.00 7.26 ? 49 TYR L C 1 ATOM 3446 O O . TYR B 2 49 ? 45.582 24.097 115.236 1.00 5.20 ? 49 TYR L O 1 ATOM 3447 C CB . TYR B 2 49 ? 48.251 25.627 113.894 1.00 5.94 ? 49 TYR L CB 1 ATOM 3448 C CG . TYR B 2 49 ? 48.223 26.210 115.272 1.00 5.88 ? 49 TYR L CG 1 ATOM 3449 C CD1 . TYR B 2 49 ? 47.725 27.463 115.414 1.00 5.81 ? 49 TYR L CD1 1 ATOM 3450 C CD2 . TYR B 2 49 ? 48.556 25.461 116.366 1.00 6.43 ? 49 TYR L CD2 1 ATOM 3451 C CE1 . TYR B 2 49 ? 47.529 27.986 116.649 1.00 5.04 ? 49 TYR L CE1 1 ATOM 3452 C CE2 . TYR B 2 49 ? 48.364 25.992 117.615 1.00 6.70 ? 49 TYR L CE2 1 ATOM 3453 C CZ . TYR B 2 49 ? 47.839 27.250 117.727 1.00 4.45 ? 49 TYR L CZ 1 ATOM 3454 O OH . TYR B 2 49 ? 47.617 27.792 118.953 1.00 5.87 ? 49 TYR L OH 1 ATOM 3455 N N . TRP B 2 50 ? 47.098 22.767 114.260 1.00 9.06 ? 50 TRP L N 1 ATOM 3456 C CA . TRP B 2 50 ? 46.735 21.507 114.932 1.00 7.51 ? 50 TRP L CA 1 ATOM 3457 C C . TRP B 2 50 ? 45.275 21.126 114.714 1.00 5.65 ? 50 TRP L C 1 ATOM 3458 O O . TRP B 2 50 ? 44.606 20.619 115.604 1.00 6.55 ? 50 TRP L O 1 ATOM 3459 C CB . TRP B 2 50 ? 47.012 21.572 116.447 1.00 6.25 ? 50 TRP L CB 1 ATOM 3460 C CG . TRP B 2 50 ? 48.467 21.317 116.795 1.00 4.66 ? 50 TRP L CG 1 ATOM 3461 C CD1 . TRP B 2 50 ? 49.287 22.304 117.252 1.00 5.47 ? 50 TRP L CD1 1 ATOM 3462 C CD2 . TRP B 2 50 ? 49.079 20.098 116.687 1.00 7.17 ? 50 TRP L CD2 1 ATOM 3463 N NE1 . TRP B 2 50 ? 50.437 21.704 117.440 1.00 5.37 ? 50 TRP L NE1 1 ATOM 3464 C CE2 . TRP B 2 50 ? 50.347 20.400 117.128 1.00 5.86 ? 50 TRP L CE2 1 ATOM 3465 C CE3 . TRP B 2 50 ? 48.724 18.821 116.290 1.00 5.57 ? 50 TRP L CE3 1 ATOM 3466 C CZ2 . TRP B 2 50 ? 51.272 19.403 117.140 1.00 5.63 ? 50 TRP L CZ2 1 ATOM 3467 C CZ3 . TRP B 2 50 ? 49.672 17.842 116.315 1.00 6.27 ? 50 TRP L CZ3 1 ATOM 3468 C CH2 . TRP B 2 50 ? 50.929 18.142 116.746 1.00 6.07 ? 50 TRP L CH2 1 ATOM 3469 N N . ALA B 2 51 ? 44.794 21.302 113.491 1.00 7.24 ? 51 ALA L N 1 ATOM 3470 C CA . ALA B 2 51 ? 43.411 21.144 113.090 1.00 6.88 ? 51 ALA L CA 1 ATOM 3471 C C . ALA B 2 51 ? 42.430 22.159 113.670 1.00 8.28 ? 51 ALA L C 1 ATOM 3472 O O . ALA B 2 51 ? 41.695 22.728 112.857 1.00 8.78 ? 51 ALA L O 1 ATOM 3473 C CB . ALA B 2 51 ? 42.846 19.783 113.446 1.00 4.40 ? 51 ALA L CB 1 ATOM 3474 N N . SER B 2 52 ? 42.353 22.435 114.977 1.00 9.78 ? 52 SER L N 1 ATOM 3475 C CA . SER B 2 52 ? 41.399 23.392 115.516 1.00 12.62 ? 52 SER L CA 1 ATOM 3476 C C . SER B 2 52 ? 41.883 24.561 116.348 1.00 13.53 ? 52 SER L C 1 ATOM 3477 O O . SER B 2 52 ? 41.051 25.315 116.876 1.00 16.89 ? 52 SER L O 1 ATOM 3478 C CB . SER B 2 52 ? 40.438 22.641 116.319 1.00 13.73 ? 52 SER L CB 1 ATOM 3479 O OG . SER B 2 52 ? 39.916 21.788 115.335 1.00 15.53 ? 52 SER L OG 1 ATOM 3480 N N . THR B 2 53 ? 43.187 24.780 116.532 1.00 12.27 ? 53 THR L N 1 ATOM 3481 C CA . THR B 2 53 ? 43.547 25.877 117.396 1.00 11.31 ? 53 THR L CA 1 ATOM 3482 C C . THR B 2 53 ? 43.569 27.124 116.551 1.00 11.93 ? 53 THR L C 1 ATOM 3483 O O . THR B 2 53 ? 44.205 27.181 115.494 1.00 13.44 ? 53 THR L O 1 ATOM 3484 C CB . THR B 2 53 ? 44.889 25.582 118.053 1.00 11.28 ? 53 THR L CB 1 ATOM 3485 O OG1 . THR B 2 53 ? 45.071 24.175 118.293 1.00 11.57 ? 53 THR L OG1 1 ATOM 3486 C CG2 . THR B 2 53 ? 44.847 26.149 119.443 1.00 11.44 ? 53 THR L CG2 1 ATOM 3487 N N . ARG B 2 54 ? 42.732 28.072 116.937 1.00 9.13 ? 54 ARG L N 1 ATOM 3488 C CA . ARG B 2 54 ? 42.711 29.305 116.197 1.00 9.49 ? 54 ARG L CA 1 ATOM 3489 C C . ARG B 2 54 ? 43.966 30.132 116.456 1.00 6.49 ? 54 ARG L C 1 ATOM 3490 O O . ARG B 2 54 ? 44.405 30.232 117.606 1.00 7.43 ? 54 ARG L O 1 ATOM 3491 C CB . ARG B 2 54 ? 41.484 30.065 116.599 1.00 9.65 ? 54 ARG L CB 1 ATOM 3492 C CG . ARG B 2 54 ? 40.257 29.665 115.772 1.00 11.48 ? 54 ARG L CG 1 ATOM 3493 C CD . ARG B 2 54 ? 38.964 30.518 115.976 1.00 12.43 ? 54 ARG L CD 1 ATOM 3494 N NE . ARG B 2 54 ? 38.089 30.116 117.075 1.00 13.23 ? 54 ARG L NE 1 ATOM 3495 C CZ . ARG B 2 54 ? 37.460 28.922 117.120 1.00 14.74 ? 54 ARG L CZ 1 ATOM 3496 N NH1 . ARG B 2 54 ? 37.532 27.927 116.205 1.00 14.06 ? 54 ARG L NH1 1 ATOM 3497 N NH2 . ARG B 2 54 ? 36.688 28.691 118.178 1.00 16.32 ? 54 ARG L NH2 1 ATOM 3498 N N . HIS B 2 55 ? 44.597 30.732 115.460 1.00 7.81 ? 55 HIS L N 1 ATOM 3499 C CA . HIS B 2 55 ? 45.695 31.631 115.760 1.00 11.78 ? 55 HIS L CA 1 ATOM 3500 C C . HIS B 2 55 ? 45.201 32.959 116.416 1.00 13.52 ? 55 HIS L C 1 ATOM 3501 O O . HIS B 2 55 ? 43.993 33.167 116.613 1.00 13.73 ? 55 HIS L O 1 ATOM 3502 C CB . HIS B 2 55 ? 46.451 31.902 114.462 1.00 9.75 ? 55 HIS L CB 1 ATOM 3503 C CG . HIS B 2 55 ? 47.737 32.727 114.593 1.00 11.05 ? 55 HIS L CG 1 ATOM 3504 N ND1 . HIS B 2 55 ? 47.937 33.937 114.057 1.00 10.62 ? 55 HIS L ND1 1 ATOM 3505 C CD2 . HIS B 2 55 ? 48.891 32.340 115.273 1.00 11.75 ? 55 HIS L CD2 1 ATOM 3506 C CE1 . HIS B 2 55 ? 49.164 34.295 114.379 1.00 11.41 ? 55 HIS L CE1 1 ATOM 3507 N NE2 . HIS B 2 55 ? 49.731 33.333 115.106 1.00 13.40 ? 55 HIS L NE2 1 ATOM 3508 N N . ILE B 2 56 ? 46.112 33.877 116.812 1.00 16.83 ? 56 ILE L N 1 ATOM 3509 C CA . ILE B 2 56 ? 45.755 35.076 117.515 1.00 19.02 ? 56 ILE L CA 1 ATOM 3510 C C . ILE B 2 56 ? 44.873 35.973 116.670 1.00 20.15 ? 56 ILE L C 1 ATOM 3511 O O . ILE B 2 56 ? 45.238 36.550 115.664 1.00 16.87 ? 56 ILE L O 1 ATOM 3512 C CB . ILE B 2 56 ? 47.111 35.800 118.056 1.00 16.51 ? 56 ILE L CB 1 ATOM 3513 C CG1 . ILE B 2 56 ? 46.753 37.178 118.563 1.00 18.45 ? 56 ILE L CG1 1 ATOM 3514 C CG2 . ILE B 2 56 ? 48.200 36.074 117.026 1.00 19.81 ? 56 ILE L CG2 1 ATOM 3515 C CD1 . ILE B 2 56 ? 46.078 37.241 119.961 1.00 19.08 ? 56 ILE L CD1 1 ATOM 3516 N N . GLY B 2 57 ? 43.611 35.868 117.041 1.00 22.66 ? 57 GLY L N 1 ATOM 3517 C CA . GLY B 2 57 ? 42.623 36.808 116.571 1.00 25.21 ? 57 GLY L CA 1 ATOM 3518 C C . GLY B 2 57 ? 42.050 36.464 115.212 1.00 25.61 ? 57 GLY L C 1 ATOM 3519 O O . GLY B 2 57 ? 41.992 37.263 114.277 1.00 26.38 ? 57 GLY L O 1 ATOM 3520 N N . VAL B 2 58 ? 41.701 35.216 115.031 1.00 25.65 ? 58 VAL L N 1 ATOM 3521 C CA . VAL B 2 58 ? 40.852 34.938 113.914 1.00 22.97 ? 58 VAL L CA 1 ATOM 3522 C C . VAL B 2 58 ? 39.562 34.661 114.708 1.00 25.50 ? 58 VAL L C 1 ATOM 3523 O O . VAL B 2 58 ? 39.554 34.160 115.846 1.00 26.87 ? 58 VAL L O 1 ATOM 3524 C CB . VAL B 2 58 ? 41.383 33.728 113.033 1.00 21.34 ? 58 VAL L CB 1 ATOM 3525 C CG1 . VAL B 2 58 ? 42.894 33.938 112.864 1.00 20.53 ? 58 VAL L CG1 1 ATOM 3526 C CG2 . VAL B 2 58 ? 40.938 32.380 113.554 1.00 19.85 ? 58 VAL L CG2 1 ATOM 3527 N N . PRO B 2 59 ? 38.425 35.143 114.224 1.00 26.54 ? 59 PRO L N 1 ATOM 3528 C CA . PRO B 2 59 ? 37.160 35.009 114.916 1.00 28.50 ? 59 PRO L CA 1 ATOM 3529 C C . PRO B 2 59 ? 36.691 33.578 114.895 1.00 29.85 ? 59 PRO L C 1 ATOM 3530 O O . PRO B 2 59 ? 36.730 32.918 113.864 1.00 29.20 ? 59 PRO L O 1 ATOM 3531 C CB . PRO B 2 59 ? 36.223 35.970 114.202 1.00 27.73 ? 59 PRO L CB 1 ATOM 3532 C CG . PRO B 2 59 ? 36.777 35.931 112.813 1.00 28.23 ? 59 PRO L CG 1 ATOM 3533 C CD . PRO B 2 59 ? 38.275 35.995 113.051 1.00 27.61 ? 59 PRO L CD 1 ATOM 3534 N N . ASP B 2 60 ? 36.243 33.174 116.070 1.00 31.44 ? 60 ASP L N 1 ATOM 3535 C CA . ASP B 2 60 ? 35.655 31.880 116.301 1.00 33.77 ? 60 ASP L CA 1 ATOM 3536 C C . ASP B 2 60 ? 34.684 31.330 115.280 1.00 31.55 ? 60 ASP L C 1 ATOM 3537 O O . ASP B 2 60 ? 34.325 30.158 115.376 1.00 32.33 ? 60 ASP L O 1 ATOM 3538 C CB . ASP B 2 60 ? 34.995 31.889 117.701 1.00 37.67 ? 60 ASP L CB 1 ATOM 3539 C CG . ASP B 2 60 ? 34.042 33.046 117.950 1.00 42.30 ? 60 ASP L CG 1 ATOM 3540 O OD1 . ASP B 2 60 ? 32.937 33.012 117.406 1.00 44.68 ? 60 ASP L OD1 1 ATOM 3541 O OD2 . ASP B 2 60 ? 34.426 33.972 118.675 1.00 44.35 ? 60 ASP L OD2 1 ATOM 3542 N N . ARG B 2 61 ? 34.225 32.108 114.311 1.00 27.13 ? 61 ARG L N 1 ATOM 3543 C CA . ARG B 2 61 ? 33.450 31.505 113.243 1.00 24.76 ? 61 ARG L CA 1 ATOM 3544 C C . ARG B 2 61 ? 34.191 30.595 112.259 1.00 23.04 ? 61 ARG L C 1 ATOM 3545 O O . ARG B 2 61 ? 33.581 29.936 111.419 1.00 26.16 ? 61 ARG L O 1 ATOM 3546 C CB . ARG B 2 61 ? 32.758 32.581 112.482 1.00 23.79 ? 61 ARG L CB 1 ATOM 3547 C CG . ARG B 2 61 ? 33.602 33.637 111.923 1.00 23.41 ? 61 ARG L CG 1 ATOM 3548 C CD . ARG B 2 61 ? 32.521 34.589 111.541 1.00 22.90 ? 61 ARG L CD 1 ATOM 3549 N NE . ARG B 2 61 ? 33.108 35.454 110.565 1.00 21.49 ? 61 ARG L NE 1 ATOM 3550 C CZ . ARG B 2 61 ? 33.121 35.129 109.284 1.00 24.03 ? 61 ARG L CZ 1 ATOM 3551 N NH1 . ARG B 2 61 ? 32.476 34.081 108.800 1.00 25.20 ? 61 ARG L NH1 1 ATOM 3552 N NH2 . ARG B 2 61 ? 33.739 35.957 108.468 1.00 26.48 ? 61 ARG L NH2 1 ATOM 3553 N N . PHE B 2 62 ? 35.510 30.529 112.342 1.00 21.03 ? 62 PHE L N 1 ATOM 3554 C CA . PHE B 2 62 ? 36.336 29.638 111.536 1.00 18.62 ? 62 PHE L CA 1 ATOM 3555 C C . PHE B 2 62 ? 36.587 28.467 112.455 1.00 16.21 ? 62 PHE L C 1 ATOM 3556 O O . PHE B 2 62 ? 37.225 28.610 113.496 1.00 13.42 ? 62 PHE L O 1 ATOM 3557 C CB . PHE B 2 62 ? 37.680 30.302 111.151 1.00 18.57 ? 62 PHE L CB 1 ATOM 3558 C CG . PHE B 2 62 ? 37.452 31.472 110.203 1.00 19.57 ? 62 PHE L CG 1 ATOM 3559 C CD1 . PHE B 2 62 ? 37.368 31.241 108.852 1.00 19.47 ? 62 PHE L CD1 1 ATOM 3560 C CD2 . PHE B 2 62 ? 37.278 32.745 110.693 1.00 19.55 ? 62 PHE L CD2 1 ATOM 3561 C CE1 . PHE B 2 62 ? 37.104 32.273 107.995 1.00 20.68 ? 62 PHE L CE1 1 ATOM 3562 C CE2 . PHE B 2 62 ? 37.011 33.781 109.835 1.00 19.86 ? 62 PHE L CE2 1 ATOM 3563 C CZ . PHE B 2 62 ? 36.924 33.543 108.485 1.00 20.06 ? 62 PHE L CZ 1 ATOM 3564 N N . ALA B 2 63 ? 36.017 27.313 112.137 1.00 16.18 ? 63 ALA L N 1 ATOM 3565 C CA . ALA B 2 63 ? 36.217 26.109 112.925 1.00 15.95 ? 63 ALA L CA 1 ATOM 3566 C C . ALA B 2 63 ? 36.819 24.995 112.103 1.00 16.12 ? 63 ALA L C 1 ATOM 3567 O O . ALA B 2 63 ? 36.292 24.679 111.030 1.00 15.78 ? 63 ALA L O 1 ATOM 3568 C CB . ALA B 2 63 ? 34.909 25.585 113.445 1.00 15.67 ? 63 ALA L CB 1 ATOM 3569 N N . GLY B 2 64 ? 37.897 24.355 112.562 1.00 17.71 ? 64 GLY L N 1 ATOM 3570 C CA . GLY B 2 64 ? 38.422 23.203 111.818 1.00 19.18 ? 64 GLY L CA 1 ATOM 3571 C C . GLY B 2 64 ? 38.154 21.899 112.550 1.00 19.84 ? 64 GLY L C 1 ATOM 3572 O O . GLY B 2 64 ? 37.836 21.938 113.739 1.00 18.79 ? 64 GLY L O 1 ATOM 3573 N N . SER B 2 65 ? 38.331 20.752 111.897 1.00 21.12 ? 65 SER L N 1 ATOM 3574 C CA . SER B 2 65 ? 38.164 19.446 112.507 1.00 21.18 ? 65 SER L CA 1 ATOM 3575 C C . SER B 2 65 ? 39.073 18.365 111.874 1.00 20.47 ? 65 SER L C 1 ATOM 3576 O O . SER B 2 65 ? 39.885 18.642 110.966 1.00 21.99 ? 65 SER L O 1 ATOM 3577 C CB . SER B 2 65 ? 36.734 19.103 112.337 1.00 21.74 ? 65 SER L CB 1 ATOM 3578 O OG . SER B 2 65 ? 36.370 18.367 113.466 1.00 26.11 ? 65 SER L OG 1 ATOM 3579 N N . GLY B 2 66 ? 39.054 17.124 112.340 1.00 19.69 ? 66 GLY L N 1 ATOM 3580 C CA . GLY B 2 66 ? 39.755 16.111 111.613 1.00 22.50 ? 66 GLY L CA 1 ATOM 3581 C C . GLY B 2 66 ? 40.462 15.153 112.499 1.00 23.54 ? 66 GLY L C 1 ATOM 3582 O O . GLY B 2 66 ? 40.596 15.333 113.704 1.00 24.78 ? 66 GLY L O 1 ATOM 3583 N N . SER B 2 67 ? 40.939 14.154 111.800 1.00 25.26 ? 67 SER L N 1 ATOM 3584 C CA . SER B 2 67 ? 41.678 13.028 112.341 1.00 25.74 ? 67 SER L CA 1 ATOM 3585 C C . SER B 2 67 ? 42.505 12.545 111.159 1.00 26.61 ? 67 SER L C 1 ATOM 3586 O O . SER B 2 67 ? 42.476 13.132 110.059 1.00 28.60 ? 67 SER L O 1 ATOM 3587 C CB . SER B 2 67 ? 40.701 11.916 112.761 1.00 27.76 ? 67 SER L CB 1 ATOM 3588 O OG . SER B 2 67 ? 40.012 11.440 111.591 1.00 28.51 ? 67 SER L OG 1 ATOM 3589 N N . GLY B 2 68 ? 43.177 11.420 111.405 1.00 25.15 ? 68 GLY L N 1 ATOM 3590 C CA . GLY B 2 68 ? 43.798 10.616 110.358 1.00 21.69 ? 68 GLY L CA 1 ATOM 3591 C C . GLY B 2 68 ? 44.344 11.408 109.196 1.00 21.85 ? 68 GLY L C 1 ATOM 3592 O O . GLY B 2 68 ? 45.284 12.186 109.374 1.00 21.69 ? 68 GLY L O 1 ATOM 3593 N N . THR B 2 69 ? 43.655 11.197 108.078 1.00 22.49 ? 69 THR L N 1 ATOM 3594 C CA . THR B 2 69 ? 43.933 11.810 106.789 1.00 21.82 ? 69 THR L CA 1 ATOM 3595 C C . THR B 2 69 ? 42.776 12.670 106.330 1.00 21.14 ? 69 THR L C 1 ATOM 3596 O O . THR B 2 69 ? 42.750 13.075 105.165 1.00 19.94 ? 69 THR L O 1 ATOM 3597 C CB . THR B 2 69 ? 44.160 10.763 105.699 1.00 21.77 ? 69 THR L CB 1 ATOM 3598 O OG1 . THR B 2 69 ? 43.162 9.768 105.824 1.00 23.16 ? 69 THR L OG1 1 ATOM 3599 C CG2 . THR B 2 69 ? 45.481 10.126 105.800 1.00 20.89 ? 69 THR L CG2 1 ATOM 3600 N N . ASP B 2 70 ? 41.778 12.941 107.174 1.00 21.03 ? 70 ASP L N 1 ATOM 3601 C CA . ASP B 2 70 ? 40.657 13.747 106.727 1.00 22.32 ? 70 ASP L CA 1 ATOM 3602 C C . ASP B 2 70 ? 40.297 14.834 107.699 1.00 20.81 ? 70 ASP L C 1 ATOM 3603 O O . ASP B 2 70 ? 39.916 14.584 108.848 1.00 22.07 ? 70 ASP L O 1 ATOM 3604 C CB . ASP B 2 70 ? 39.454 12.842 106.450 1.00 23.99 ? 70 ASP L CB 1 ATOM 3605 C CG . ASP B 2 70 ? 39.560 12.461 104.979 1.00 25.00 ? 70 ASP L CG 1 ATOM 3606 O OD1 . ASP B 2 70 ? 39.223 13.277 104.106 1.00 26.42 ? 70 ASP L OD1 1 ATOM 3607 O OD2 . ASP B 2 70 ? 40.029 11.354 104.709 1.00 26.66 ? 70 ASP L OD2 1 ATOM 3608 N N . TYR B 2 71 ? 40.499 16.036 107.172 1.00 18.15 ? 71 TYR L N 1 ATOM 3609 C CA . TYR B 2 71 ? 40.325 17.293 107.877 1.00 14.44 ? 71 TYR L CA 1 ATOM 3610 C C . TYR B 2 71 ? 39.341 18.180 107.110 1.00 14.55 ? 71 TYR L C 1 ATOM 3611 O O . TYR B 2 71 ? 39.098 17.982 105.914 1.00 15.10 ? 71 TYR L O 1 ATOM 3612 C CB . TYR B 2 71 ? 41.722 17.994 108.010 1.00 12.26 ? 71 TYR L CB 1 ATOM 3613 C CG . TYR B 2 71 ? 42.692 17.149 108.834 1.00 10.03 ? 71 TYR L CG 1 ATOM 3614 C CD1 . TYR B 2 71 ? 42.689 17.192 110.228 1.00 8.14 ? 71 TYR L CD1 1 ATOM 3615 C CD2 . TYR B 2 71 ? 43.542 16.282 108.165 1.00 9.76 ? 71 TYR L CD2 1 ATOM 3616 C CE1 . TYR B 2 71 ? 43.524 16.349 110.953 1.00 8.58 ? 71 TYR L CE1 1 ATOM 3617 C CE2 . TYR B 2 71 ? 44.366 15.452 108.871 1.00 8.90 ? 71 TYR L CE2 1 ATOM 3618 C CZ . TYR B 2 71 ? 44.353 15.476 110.258 1.00 8.61 ? 71 TYR L CZ 1 ATOM 3619 O OH . TYR B 2 71 ? 45.122 14.549 110.957 1.00 8.73 ? 71 TYR L OH 1 ATOM 3620 N N . THR B 2 72 ? 38.735 19.158 107.763 1.00 13.64 ? 72 THR L N 1 ATOM 3621 C CA . THR B 2 72 ? 37.849 20.079 107.087 1.00 13.18 ? 72 THR L CA 1 ATOM 3622 C C . THR B 2 72 ? 37.795 21.473 107.757 1.00 12.85 ? 72 THR L C 1 ATOM 3623 O O . THR B 2 72 ? 37.859 21.505 108.997 1.00 13.25 ? 72 THR L O 1 ATOM 3624 C CB . THR B 2 72 ? 36.480 19.353 107.020 1.00 13.99 ? 72 THR L CB 1 ATOM 3625 O OG1 . THR B 2 72 ? 35.587 20.328 106.493 1.00 17.55 ? 72 THR L OG1 1 ATOM 3626 C CG2 . THR B 2 72 ? 36.001 18.752 108.324 1.00 16.79 ? 72 THR L CG2 1 ATOM 3627 N N . LEU B 2 73 ? 37.783 22.616 107.043 1.00 9.23 ? 73 LEU L N 1 ATOM 3628 C CA . LEU B 2 73 ? 37.579 23.906 107.672 1.00 8.93 ? 73 LEU L CA 1 ATOM 3629 C C . LEU B 2 73 ? 36.116 24.308 107.416 1.00 10.04 ? 73 LEU L C 1 ATOM 3630 O O . LEU B 2 73 ? 35.617 24.177 106.293 1.00 7.71 ? 73 LEU L O 1 ATOM 3631 C CB . LEU B 2 73 ? 38.537 24.940 107.065 1.00 7.19 ? 73 LEU L CB 1 ATOM 3632 C CG . LEU B 2 73 ? 38.373 26.466 107.257 1.00 3.90 ? 73 LEU L CG 1 ATOM 3633 C CD1 . LEU B 2 73 ? 38.824 26.920 108.616 1.00 3.39 ? 73 LEU L CD1 1 ATOM 3634 C CD2 . LEU B 2 73 ? 39.244 27.182 106.251 1.00 2.05 ? 73 LEU L CD2 1 ATOM 3635 N N . THR B 2 74 ? 35.374 24.758 108.427 1.00 13.45 ? 74 THR L N 1 ATOM 3636 C CA . THR B 2 74 ? 34.027 25.309 108.330 1.00 14.81 ? 74 THR L CA 1 ATOM 3637 C C . THR B 2 74 ? 34.034 26.820 108.609 1.00 16.90 ? 74 THR L C 1 ATOM 3638 O O . THR B 2 74 ? 34.672 27.328 109.536 1.00 19.48 ? 74 THR L O 1 ATOM 3639 C CB . THR B 2 74 ? 33.120 24.585 109.348 1.00 16.12 ? 74 THR L CB 1 ATOM 3640 O OG1 . THR B 2 74 ? 32.921 23.248 108.880 1.00 18.49 ? 74 THR L OG1 1 ATOM 3641 C CG2 . THR B 2 74 ? 31.748 25.244 109.486 1.00 17.24 ? 74 THR L CG2 1 ATOM 3642 N N . ILE B 2 75 ? 33.304 27.591 107.835 1.00 18.52 ? 75 ILE L N 1 ATOM 3643 C CA . ILE B 2 75 ? 33.180 29.024 108.047 1.00 19.05 ? 75 ILE L CA 1 ATOM 3644 C C . ILE B 2 75 ? 31.678 29.164 108.242 1.00 21.98 ? 75 ILE L C 1 ATOM 3645 O O . ILE B 2 75 ? 30.912 28.614 107.430 1.00 22.27 ? 75 ILE L O 1 ATOM 3646 C CB . ILE B 2 75 ? 33.571 29.822 106.801 1.00 17.26 ? 75 ILE L CB 1 ATOM 3647 C CG1 . ILE B 2 75 ? 35.009 29.520 106.400 1.00 16.56 ? 75 ILE L CG1 1 ATOM 3648 C CG2 . ILE B 2 75 ? 33.277 31.305 107.088 1.00 16.67 ? 75 ILE L CG2 1 ATOM 3649 C CD1 . ILE B 2 75 ? 35.440 30.011 105.010 1.00 15.27 ? 75 ILE L CD1 1 ATOM 3650 N N . SER B 2 76 ? 31.222 29.863 109.262 1.00 26.10 ? 76 SER L N 1 ATOM 3651 C CA . SER B 2 76 ? 29.796 30.086 109.464 1.00 28.17 ? 76 SER L CA 1 ATOM 3652 C C . SER B 2 76 ? 29.515 31.586 109.292 1.00 28.56 ? 76 SER L C 1 ATOM 3653 O O . SER B 2 76 ? 30.427 32.404 109.395 1.00 29.25 ? 76 SER L O 1 ATOM 3654 C CB . SER B 2 76 ? 29.426 29.586 110.865 1.00 29.40 ? 76 SER L CB 1 ATOM 3655 O OG . SER B 2 76 ? 30.162 28.440 111.322 1.00 31.05 ? 76 SER L OG 1 ATOM 3656 N N . SER B 2 77 ? 28.299 32.016 108.981 1.00 27.04 ? 77 SER L N 1 ATOM 3657 C CA . SER B 2 77 ? 27.945 33.422 108.829 1.00 25.87 ? 77 SER L CA 1 ATOM 3658 C C . SER B 2 77 ? 28.852 34.238 107.920 1.00 25.65 ? 77 SER L C 1 ATOM 3659 O O . SER B 2 77 ? 29.224 35.395 108.180 1.00 25.47 ? 77 SER L O 1 ATOM 3660 C CB . SER B 2 77 ? 27.889 34.068 110.188 1.00 28.21 ? 77 SER L CB 1 ATOM 3661 O OG . SER B 2 77 ? 26.575 34.558 110.418 1.00 30.00 ? 77 SER L OG 1 ATOM 3662 N N . VAL B 2 78 ? 29.006 33.601 106.747 1.00 23.58 ? 78 VAL L N 1 ATOM 3663 C CA . VAL B 2 78 ? 29.930 34.026 105.705 1.00 20.28 ? 78 VAL L CA 1 ATOM 3664 C C . VAL B 2 78 ? 29.624 35.429 105.218 1.00 21.29 ? 78 VAL L C 1 ATOM 3665 O O . VAL B 2 78 ? 28.518 35.821 104.866 1.00 23.48 ? 78 VAL L O 1 ATOM 3666 C CB . VAL B 2 78 ? 29.901 32.985 104.563 1.00 18.86 ? 78 VAL L CB 1 ATOM 3667 C CG1 . VAL B 2 78 ? 31.255 32.985 103.905 1.00 18.92 ? 78 VAL L CG1 1 ATOM 3668 C CG2 . VAL B 2 78 ? 29.825 31.551 105.051 1.00 17.86 ? 78 VAL L CG2 1 ATOM 3669 N N . GLN B 2 79 ? 30.657 36.189 105.574 1.00 23.13 ? 79 GLN L N 1 ATOM 3670 C CA . GLN B 2 79 ? 30.815 37.625 105.370 1.00 24.45 ? 79 GLN L CA 1 ATOM 3671 C C . GLN B 2 79 ? 31.066 37.778 103.864 1.00 24.70 ? 79 GLN L C 1 ATOM 3672 O O . GLN B 2 79 ? 31.667 36.896 103.255 1.00 26.57 ? 79 GLN L O 1 ATOM 3673 C CB . GLN B 2 79 ? 32.065 38.126 106.202 1.00 28.27 ? 79 GLN L CB 1 ATOM 3674 C CG . GLN B 2 79 ? 32.154 39.161 107.363 1.00 30.36 ? 79 GLN L CG 1 ATOM 3675 C CD . GLN B 2 79 ? 31.578 38.852 108.769 1.00 31.99 ? 79 GLN L CD 1 ATOM 3676 O OE1 . GLN B 2 79 ? 31.677 39.659 109.714 1.00 32.90 ? 79 GLN L OE1 1 ATOM 3677 N NE2 . GLN B 2 79 ? 30.878 37.744 109.040 1.00 33.13 ? 79 GLN L NE2 1 ATOM 3678 N N . ALA B 2 80 ? 30.744 38.886 103.216 1.00 24.76 ? 80 ALA L N 1 ATOM 3679 C CA . ALA B 2 80 ? 31.040 39.052 101.807 1.00 24.26 ? 80 ALA L CA 1 ATOM 3680 C C . ALA B 2 80 ? 32.545 39.027 101.581 1.00 25.30 ? 80 ALA L C 1 ATOM 3681 O O . ALA B 2 80 ? 33.021 38.608 100.531 1.00 25.30 ? 80 ALA L O 1 ATOM 3682 C CB . ALA B 2 80 ? 30.476 40.362 101.356 1.00 22.94 ? 80 ALA L CB 1 ATOM 3683 N N . GLU B 2 81 ? 33.291 39.435 102.621 1.00 26.79 ? 81 GLU L N 1 ATOM 3684 C CA . GLU B 2 81 ? 34.743 39.425 102.643 1.00 28.62 ? 81 GLU L CA 1 ATOM 3685 C C . GLU B 2 81 ? 35.414 38.114 103.066 1.00 27.10 ? 81 GLU L C 1 ATOM 3686 O O . GLU B 2 81 ? 36.603 38.093 103.369 1.00 29.32 ? 81 GLU L O 1 ATOM 3687 C CB . GLU B 2 81 ? 35.258 40.595 103.538 1.00 32.75 ? 81 GLU L CB 1 ATOM 3688 C CG . GLU B 2 81 ? 35.183 42.017 102.847 1.00 38.33 ? 81 GLU L CG 1 ATOM 3689 C CD . GLU B 2 81 ? 35.873 43.285 103.438 1.00 42.19 ? 81 GLU L CD 1 ATOM 3690 O OE1 . GLU B 2 81 ? 36.618 43.176 104.432 1.00 43.35 ? 81 GLU L OE1 1 ATOM 3691 O OE2 . GLU B 2 81 ? 35.666 44.391 102.892 1.00 44.18 ? 81 GLU L OE2 1 ATOM 3692 N N . ASP B 2 82 ? 34.749 36.964 103.120 1.00 23.46 ? 82 ASP L N 1 ATOM 3693 C CA . ASP B 2 82 ? 35.517 35.742 103.263 1.00 20.07 ? 82 ASP L CA 1 ATOM 3694 C C . ASP B 2 82 ? 35.937 35.199 101.886 1.00 19.39 ? 82 ASP L C 1 ATOM 3695 O O . ASP B 2 82 ? 36.571 34.144 101.804 1.00 21.72 ? 82 ASP L O 1 ATOM 3696 C CB . ASP B 2 82 ? 34.699 34.738 103.978 1.00 17.64 ? 82 ASP L CB 1 ATOM 3697 C CG . ASP B 2 82 ? 34.475 35.067 105.454 1.00 17.77 ? 82 ASP L CG 1 ATOM 3698 O OD1 . ASP B 2 82 ? 35.378 35.531 106.174 1.00 13.55 ? 82 ASP L OD1 1 ATOM 3699 O OD2 . ASP B 2 82 ? 33.363 34.810 105.906 1.00 19.78 ? 82 ASP L OD2 1 ATOM 3700 N N . LEU B 2 83 ? 35.637 35.871 100.758 1.00 18.34 ? 83 LEU L N 1 ATOM 3701 C CA . LEU B 2 83 ? 36.005 35.462 99.402 1.00 18.64 ? 83 LEU L CA 1 ATOM 3702 C C . LEU B 2 83 ? 37.525 35.473 99.341 1.00 17.61 ? 83 LEU L C 1 ATOM 3703 O O . LEU B 2 83 ? 38.082 36.568 99.447 1.00 19.97 ? 83 LEU L O 1 ATOM 3704 C CB . LEU B 2 83 ? 35.461 36.457 98.362 1.00 19.15 ? 83 LEU L CB 1 ATOM 3705 C CG . LEU B 2 83 ? 36.043 36.405 96.932 1.00 19.87 ? 83 LEU L CG 1 ATOM 3706 C CD1 . LEU B 2 83 ? 35.228 35.495 96.006 1.00 21.74 ? 83 LEU L CD1 1 ATOM 3707 C CD2 . LEU B 2 83 ? 36.090 37.817 96.420 1.00 19.92 ? 83 LEU L CD2 1 ATOM 3708 N N . ALA B 2 84 ? 38.172 34.308 99.222 1.00 14.88 ? 84 ALA L N 1 ATOM 3709 C CA . ALA B 2 84 ? 39.608 34.123 99.270 1.00 12.14 ? 84 ALA L CA 1 ATOM 3710 C C . ALA B 2 84 ? 39.842 32.648 98.959 1.00 13.05 ? 84 ALA L C 1 ATOM 3711 O O . ALA B 2 84 ? 38.920 31.819 98.777 1.00 12.35 ? 84 ALA L O 1 ATOM 3712 C CB . ALA B 2 84 ? 40.178 34.357 100.650 1.00 12.31 ? 84 ALA L CB 1 ATOM 3713 N N . LEU B 2 85 ? 41.126 32.326 98.871 1.00 12.85 ? 85 LEU L N 1 ATOM 3714 C CA . LEU B 2 85 ? 41.571 30.979 98.625 1.00 12.08 ? 85 LEU L CA 1 ATOM 3715 C C . LEU B 2 85 ? 41.958 30.336 99.961 1.00 14.52 ? 85 LEU L C 1 ATOM 3716 O O . LEU B 2 85 ? 42.691 30.974 100.728 1.00 16.39 ? 85 LEU L O 1 ATOM 3717 C CB . LEU B 2 85 ? 42.717 31.122 97.700 1.00 13.72 ? 85 LEU L CB 1 ATOM 3718 C CG . LEU B 2 85 ? 42.608 30.743 96.242 1.00 12.55 ? 85 LEU L CG 1 ATOM 3719 C CD1 . LEU B 2 85 ? 43.941 31.112 95.545 1.00 11.77 ? 85 LEU L CD1 1 ATOM 3720 C CD2 . LEU B 2 85 ? 42.322 29.248 96.115 1.00 10.84 ? 85 LEU L CD2 1 ATOM 3721 N N . TYR B 2 86 ? 41.491 29.153 100.348 1.00 12.09 ? 86 TYR L N 1 ATOM 3722 C CA . TYR B 2 86 ? 41.850 28.574 101.638 1.00 12.30 ? 86 TYR L CA 1 ATOM 3723 C C . TYR B 2 86 ? 42.794 27.435 101.382 1.00 14.22 ? 86 TYR L C 1 ATOM 3724 O O . TYR B 2 86 ? 42.557 26.636 100.460 1.00 17.67 ? 86 TYR L O 1 ATOM 3725 C CB . TYR B 2 86 ? 40.585 28.087 102.346 1.00 13.20 ? 86 TYR L CB 1 ATOM 3726 C CG . TYR B 2 86 ? 39.790 29.294 102.802 1.00 12.74 ? 86 TYR L CG 1 ATOM 3727 C CD1 . TYR B 2 86 ? 40.113 29.854 104.015 1.00 13.64 ? 86 TYR L CD1 1 ATOM 3728 C CD2 . TYR B 2 86 ? 38.823 29.868 102.001 1.00 13.31 ? 86 TYR L CD2 1 ATOM 3729 C CE1 . TYR B 2 86 ? 39.470 30.996 104.426 1.00 14.53 ? 86 TYR L CE1 1 ATOM 3730 C CE2 . TYR B 2 86 ? 38.181 31.023 102.405 1.00 13.30 ? 86 TYR L CE2 1 ATOM 3731 C CZ . TYR B 2 86 ? 38.519 31.578 103.621 1.00 13.65 ? 86 TYR L CZ 1 ATOM 3732 O OH . TYR B 2 86 ? 37.944 32.743 104.075 1.00 10.92 ? 86 TYR L OH 1 ATOM 3733 N N . TYR B 2 87 ? 43.851 27.323 102.184 1.00 13.80 ? 87 TYR L N 1 ATOM 3734 C CA . TYR B 2 87 ? 44.930 26.355 101.919 1.00 12.19 ? 87 TYR L CA 1 ATOM 3735 C C . TYR B 2 87 ? 45.232 25.474 103.089 1.00 9.54 ? 87 TYR L C 1 ATOM 3736 O O . TYR B 2 87 ? 45.400 26.005 104.181 1.00 7.21 ? 87 TYR L O 1 ATOM 3737 C CB . TYR B 2 87 ? 46.258 26.996 101.595 1.00 9.53 ? 87 TYR L CB 1 ATOM 3738 C CG . TYR B 2 87 ? 46.318 27.708 100.276 1.00 10.40 ? 87 TYR L CG 1 ATOM 3739 C CD1 . TYR B 2 87 ? 46.626 26.962 99.196 1.00 12.85 ? 87 TYR L CD1 1 ATOM 3740 C CD2 . TYR B 2 87 ? 46.155 29.072 100.184 1.00 11.70 ? 87 TYR L CD2 1 ATOM 3741 C CE1 . TYR B 2 87 ? 46.792 27.585 97.992 1.00 13.20 ? 87 TYR L CE1 1 ATOM 3742 C CE2 . TYR B 2 87 ? 46.317 29.714 98.978 1.00 13.86 ? 87 TYR L CE2 1 ATOM 3743 C CZ . TYR B 2 87 ? 46.646 28.945 97.886 1.00 14.68 ? 87 TYR L CZ 1 ATOM 3744 O OH . TYR B 2 87 ? 46.882 29.496 96.651 1.00 16.02 ? 87 TYR L OH 1 ATOM 3745 N N . CYS B 2 88 ? 45.280 24.163 102.931 1.00 8.24 ? 88 CYS L N 1 ATOM 3746 C CA . CYS B 2 88 ? 45.741 23.358 104.055 1.00 8.30 ? 88 CYS L CA 1 ATOM 3747 C C . CYS B 2 88 ? 47.195 23.048 103.795 1.00 7.93 ? 88 CYS L C 1 ATOM 3748 O O . CYS B 2 88 ? 47.648 23.061 102.654 1.00 5.06 ? 88 CYS L O 1 ATOM 3749 C CB . CYS B 2 88 ? 44.952 22.060 104.220 1.00 5.76 ? 88 CYS L CB 1 ATOM 3750 S SG . CYS B 2 88 ? 45.065 20.864 102.891 1.00 9.70 ? 88 CYS L SG 1 ATOM 3751 N N . GLN B 2 89 ? 47.911 22.929 104.898 1.00 6.66 ? 89 GLN L N 1 ATOM 3752 C CA . GLN B 2 89 ? 49.337 22.697 104.924 1.00 6.12 ? 89 GLN L CA 1 ATOM 3753 C C . GLN B 2 89 ? 49.399 21.508 105.853 1.00 7.43 ? 89 GLN L C 1 ATOM 3754 O O . GLN B 2 89 ? 48.446 21.251 106.593 1.00 9.98 ? 89 GLN L O 1 ATOM 3755 C CB . GLN B 2 89 ? 50.095 23.834 105.585 1.00 5.14 ? 89 GLN L CB 1 ATOM 3756 C CG . GLN B 2 89 ? 51.542 23.650 105.337 1.00 3.23 ? 89 GLN L CG 1 ATOM 3757 C CD . GLN B 2 89 ? 52.468 24.377 106.258 1.00 4.92 ? 89 GLN L CD 1 ATOM 3758 O OE1 . GLN B 2 89 ? 52.758 25.556 106.120 1.00 8.69 ? 89 GLN L OE1 1 ATOM 3759 N NE2 . GLN B 2 89 ? 52.985 23.675 107.237 1.00 6.67 ? 89 GLN L NE2 1 ATOM 3760 N N . GLN B 2 90 ? 50.505 20.792 105.883 1.00 8.64 ? 90 GLN L N 1 ATOM 3761 C CA . GLN B 2 90 ? 50.670 19.700 106.804 1.00 9.24 ? 90 GLN L CA 1 ATOM 3762 C C . GLN B 2 90 ? 51.762 20.200 107.709 1.00 10.50 ? 90 GLN L C 1 ATOM 3763 O O . GLN B 2 90 ? 52.687 20.865 107.230 1.00 12.39 ? 90 GLN L O 1 ATOM 3764 C CB . GLN B 2 90 ? 51.041 18.534 105.951 1.00 10.34 ? 90 GLN L CB 1 ATOM 3765 C CG . GLN B 2 90 ? 51.639 17.303 106.539 1.00 9.65 ? 90 GLN L CG 1 ATOM 3766 C CD . GLN B 2 90 ? 53.144 17.371 106.582 1.00 11.24 ? 90 GLN L CD 1 ATOM 3767 O OE1 . GLN B 2 90 ? 53.660 17.040 107.650 1.00 13.08 ? 90 GLN L OE1 1 ATOM 3768 N NE2 . GLN B 2 90 ? 53.893 17.801 105.560 1.00 9.87 ? 90 GLN L NE2 1 ATOM 3769 N N . HIS B 2 91 ? 51.722 19.953 109.009 1.00 10.58 ? 91 HIS L N 1 ATOM 3770 C CA . HIS B 2 91 ? 52.786 20.457 109.855 1.00 11.60 ? 91 HIS L CA 1 ATOM 3771 C C . HIS B 2 91 ? 53.442 19.409 110.793 1.00 13.19 ? 91 HIS L C 1 ATOM 3772 O O . HIS B 2 91 ? 53.957 19.712 111.877 1.00 10.35 ? 91 HIS L O 1 ATOM 3773 C CB . HIS B 2 91 ? 52.171 21.732 110.576 1.00 10.74 ? 91 HIS L CB 1 ATOM 3774 C CG . HIS B 2 91 ? 51.416 21.664 111.898 1.00 9.39 ? 91 HIS L CG 1 ATOM 3775 N ND1 . HIS B 2 91 ? 51.258 20.683 112.765 1.00 11.94 ? 91 HIS L ND1 1 ATOM 3776 C CD2 . HIS B 2 91 ? 50.796 22.731 112.459 1.00 9.56 ? 91 HIS L CD2 1 ATOM 3777 C CE1 . HIS B 2 91 ? 50.584 21.110 113.794 1.00 9.53 ? 91 HIS L CE1 1 ATOM 3778 N NE2 . HIS B 2 91 ? 50.306 22.358 113.602 1.00 7.98 ? 91 HIS L NE2 1 ATOM 3779 N N . TYR B 2 92 ? 53.559 18.175 110.272 1.00 15.93 ? 92 TYR L N 1 ATOM 3780 C CA . TYR B 2 92 ? 53.982 17.005 111.024 1.00 16.02 ? 92 TYR L CA 1 ATOM 3781 C C . TYR B 2 92 ? 55.410 16.595 110.794 1.00 18.64 ? 92 TYR L C 1 ATOM 3782 O O . TYR B 2 92 ? 56.130 16.391 111.760 1.00 19.43 ? 92 TYR L O 1 ATOM 3783 C CB . TYR B 2 92 ? 53.046 15.874 110.671 1.00 15.21 ? 92 TYR L CB 1 ATOM 3784 C CG . TYR B 2 92 ? 53.384 14.508 111.240 1.00 15.51 ? 92 TYR L CG 1 ATOM 3785 C CD1 . TYR B 2 92 ? 53.084 14.273 112.545 1.00 14.95 ? 92 TYR L CD1 1 ATOM 3786 C CD2 . TYR B 2 92 ? 53.992 13.527 110.480 1.00 13.78 ? 92 TYR L CD2 1 ATOM 3787 C CE1 . TYR B 2 92 ? 53.383 13.066 113.121 1.00 15.30 ? 92 TYR L CE1 1 ATOM 3788 C CE2 . TYR B 2 92 ? 54.288 12.313 111.054 1.00 14.87 ? 92 TYR L CE2 1 ATOM 3789 C CZ . TYR B 2 92 ? 53.982 12.079 112.390 1.00 15.63 ? 92 TYR L CZ 1 ATOM 3790 O OH . TYR B 2 92 ? 54.263 10.876 113.055 1.00 14.46 ? 92 TYR L OH 1 ATOM 3791 N N . SER B 2 93 ? 55.805 16.348 109.567 1.00 20.36 ? 93 SER L N 1 ATOM 3792 C CA . SER B 2 93 ? 57.184 16.044 109.307 1.00 19.56 ? 93 SER L CA 1 ATOM 3793 C C . SER B 2 93 ? 57.579 16.661 107.973 1.00 19.38 ? 93 SER L C 1 ATOM 3794 O O . SER B 2 93 ? 56.743 16.741 107.081 1.00 21.65 ? 93 SER L O 1 ATOM 3795 C CB . SER B 2 93 ? 57.375 14.543 109.286 1.00 22.27 ? 93 SER L CB 1 ATOM 3796 O OG . SER B 2 93 ? 56.521 13.921 108.339 1.00 26.11 ? 93 SER L OG 1 ATOM 3797 N N . PRO B 2 94 ? 58.787 17.177 107.783 1.00 17.08 ? 94 PRO L N 1 ATOM 3798 C CA . PRO B 2 94 ? 59.277 17.723 106.538 1.00 17.31 ? 94 PRO L CA 1 ATOM 3799 C C . PRO B 2 94 ? 59.106 16.931 105.256 1.00 17.49 ? 94 PRO L C 1 ATOM 3800 O O . PRO B 2 94 ? 58.987 15.703 105.356 1.00 15.79 ? 94 PRO L O 1 ATOM 3801 C CB . PRO B 2 94 ? 60.700 18.011 106.830 1.00 16.51 ? 94 PRO L CB 1 ATOM 3802 C CG . PRO B 2 94 ? 60.607 18.484 108.239 1.00 16.79 ? 94 PRO L CG 1 ATOM 3803 C CD . PRO B 2 94 ? 59.759 17.405 108.836 1.00 16.81 ? 94 PRO L CD 1 ATOM 3804 N N . PRO B 2 95 ? 59.067 17.626 104.070 1.00 16.90 ? 95 PRO L N 1 ATOM 3805 C CA . PRO B 2 95 ? 58.815 19.059 103.964 1.00 15.45 ? 95 PRO L CA 1 ATOM 3806 C C . PRO B 2 95 ? 57.325 19.313 104.198 1.00 14.14 ? 95 PRO L C 1 ATOM 3807 O O . PRO B 2 95 ? 56.444 18.437 104.148 1.00 13.44 ? 95 PRO L O 1 ATOM 3808 C CB . PRO B 2 95 ? 59.260 19.430 102.566 1.00 17.14 ? 95 PRO L CB 1 ATOM 3809 C CG . PRO B 2 95 ? 59.629 18.134 101.885 1.00 16.44 ? 95 PRO L CG 1 ATOM 3810 C CD . PRO B 2 95 ? 58.964 17.079 102.717 1.00 17.00 ? 95 PRO L CD 1 ATOM 3811 N N . TRP B 2 96 ? 57.131 20.564 104.565 1.00 13.61 ? 96 TRP L N 1 ATOM 3812 C CA . TRP B 2 96 ? 55.795 21.136 104.726 1.00 10.75 ? 96 TRP L CA 1 ATOM 3813 C C . TRP B 2 96 ? 55.156 21.356 103.348 1.00 9.08 ? 96 TRP L C 1 ATOM 3814 O O . TRP B 2 96 ? 55.571 22.190 102.516 1.00 10.34 ? 96 TRP L O 1 ATOM 3815 C CB . TRP B 2 96 ? 55.891 22.460 105.465 1.00 8.36 ? 96 TRP L CB 1 ATOM 3816 C CG . TRP B 2 96 ? 56.947 22.441 106.558 1.00 6.09 ? 96 TRP L CG 1 ATOM 3817 C CD1 . TRP B 2 96 ? 57.862 23.462 106.655 1.00 6.44 ? 96 TRP L CD1 1 ATOM 3818 C CD2 . TRP B 2 96 ? 57.084 21.488 107.531 1.00 6.47 ? 96 TRP L CD2 1 ATOM 3819 N NE1 . TRP B 2 96 ? 58.586 23.172 107.719 1.00 7.15 ? 96 TRP L NE1 1 ATOM 3820 C CE2 . TRP B 2 96 ? 58.157 22.017 108.264 1.00 7.37 ? 96 TRP L CE2 1 ATOM 3821 C CE3 . TRP B 2 96 ? 56.468 20.308 107.897 1.00 6.83 ? 96 TRP L CE3 1 ATOM 3822 C CZ2 . TRP B 2 96 ? 58.651 21.372 109.378 1.00 8.07 ? 96 TRP L CZ2 1 ATOM 3823 C CZ3 . TRP B 2 96 ? 56.974 19.686 109.019 1.00 7.16 ? 96 TRP L CZ3 1 ATOM 3824 C CH2 . TRP B 2 96 ? 58.028 20.199 109.749 1.00 7.65 ? 96 TRP L CH2 1 ATOM 3825 N N . THR B 2 97 ? 54.227 20.422 103.116 1.00 10.57 ? 97 THR L N 1 ATOM 3826 C CA . THR B 2 97 ? 53.422 20.341 101.910 1.00 11.23 ? 97 THR L CA 1 ATOM 3827 C C . THR B 2 97 ? 52.068 21.044 102.112 1.00 11.77 ? 97 THR L C 1 ATOM 3828 O O . THR B 2 97 ? 51.510 21.083 103.230 1.00 12.94 ? 97 THR L O 1 ATOM 3829 C CB . THR B 2 97 ? 53.218 18.873 101.560 1.00 10.66 ? 97 THR L CB 1 ATOM 3830 O OG1 . THR B 2 97 ? 52.925 18.284 102.818 1.00 12.45 ? 97 THR L OG1 1 ATOM 3831 C CG2 . THR B 2 97 ? 54.405 18.172 100.904 1.00 12.78 ? 97 THR L CG2 1 ATOM 3832 N N . PHE B 2 98 ? 51.574 21.644 101.026 1.00 10.49 ? 98 PHE L N 1 ATOM 3833 C CA . PHE B 2 98 ? 50.328 22.356 101.002 1.00 14.42 ? 98 PHE L CA 1 ATOM 3834 C C . PHE B 2 98 ? 49.260 21.619 100.195 1.00 14.97 ? 98 PHE L C 1 ATOM 3835 O O . PHE B 2 98 ? 49.534 20.632 99.526 1.00 18.12 ? 98 PHE L O 1 ATOM 3836 C CB . PHE B 2 98 ? 50.584 23.715 100.392 1.00 11.45 ? 98 PHE L CB 1 ATOM 3837 C CG . PHE B 2 98 ? 51.415 24.672 101.214 1.00 9.98 ? 98 PHE L CG 1 ATOM 3838 C CD1 . PHE B 2 98 ? 50.802 25.515 102.086 1.00 10.22 ? 98 PHE L CD1 1 ATOM 3839 C CD2 . PHE B 2 98 ? 52.775 24.728 101.085 1.00 8.10 ? 98 PHE L CD2 1 ATOM 3840 C CE1 . PHE B 2 98 ? 51.573 26.407 102.809 1.00 11.05 ? 98 PHE L CE1 1 ATOM 3841 C CE2 . PHE B 2 98 ? 53.521 25.632 101.809 1.00 8.54 ? 98 PHE L CE2 1 ATOM 3842 C CZ . PHE B 2 98 ? 52.938 26.476 102.685 1.00 10.47 ? 98 PHE L CZ 1 ATOM 3843 N N . GLY B 2 99 ? 48.019 22.041 100.247 1.00 15.36 ? 99 GLY L N 1 ATOM 3844 C CA . GLY B 2 99 ? 46.968 21.530 99.391 1.00 15.72 ? 99 GLY L CA 1 ATOM 3845 C C . GLY B 2 99 ? 46.760 22.534 98.234 1.00 15.30 ? 99 GLY L C 1 ATOM 3846 O O . GLY B 2 99 ? 47.263 23.662 98.285 1.00 17.33 ? 99 GLY L O 1 ATOM 3847 N N . GLY B 2 100 ? 46.073 22.190 97.129 1.00 13.52 ? 100 GLY L N 1 ATOM 3848 C CA . GLY B 2 100 ? 45.825 23.135 96.043 1.00 12.35 ? 100 GLY L CA 1 ATOM 3849 C C . GLY B 2 100 ? 45.124 24.474 96.371 1.00 14.15 ? 100 GLY L C 1 ATOM 3850 O O . GLY B 2 100 ? 45.154 25.363 95.510 1.00 14.18 ? 100 GLY L O 1 ATOM 3851 N N . GLY B 2 101 ? 44.540 24.761 97.543 1.00 10.67 ? 101 GLY L N 1 ATOM 3852 C CA . GLY B 2 101 ? 43.774 25.980 97.695 1.00 9.24 ? 101 GLY L CA 1 ATOM 3853 C C . GLY B 2 101 ? 42.356 25.791 97.142 1.00 10.25 ? 101 GLY L C 1 ATOM 3854 O O . GLY B 2 101 ? 42.162 25.255 96.062 1.00 9.91 ? 101 GLY L O 1 ATOM 3855 N N . THR B 2 102 ? 41.324 26.188 97.879 1.00 10.44 ? 102 THR L N 1 ATOM 3856 C CA . THR B 2 102 ? 39.976 26.125 97.414 1.00 5.82 ? 102 THR L CA 1 ATOM 3857 C C . THR B 2 102 ? 39.530 27.564 97.418 1.00 9.11 ? 102 THR L C 1 ATOM 3858 O O . THR B 2 102 ? 39.811 28.331 98.329 1.00 9.44 ? 102 THR L O 1 ATOM 3859 C CB . THR B 2 102 ? 39.172 25.281 98.357 1.00 5.47 ? 102 THR L CB 1 ATOM 3860 O OG1 . THR B 2 102 ? 39.621 23.965 98.146 1.00 2.00 ? 102 THR L OG1 1 ATOM 3861 C CG2 . THR B 2 102 ? 37.700 25.324 98.131 1.00 4.64 ? 102 THR L CG2 1 ATOM 3862 N N . LYS B 2 103 ? 38.909 27.948 96.320 1.00 13.51 ? 103 LYS L N 1 ATOM 3863 C CA . LYS B 2 103 ? 38.405 29.271 96.115 1.00 18.18 ? 103 LYS L CA 1 ATOM 3864 C C . LYS B 2 103 ? 36.990 29.229 96.628 1.00 19.49 ? 103 LYS L C 1 ATOM 3865 O O . LYS B 2 103 ? 36.276 28.258 96.335 1.00 18.53 ? 103 LYS L O 1 ATOM 3866 C CB . LYS B 2 103 ? 38.420 29.552 94.657 1.00 21.60 ? 103 LYS L CB 1 ATOM 3867 C CG . LYS B 2 103 ? 38.991 30.902 94.473 1.00 28.72 ? 103 LYS L CG 1 ATOM 3868 C CD . LYS B 2 103 ? 38.094 31.702 93.596 1.00 33.40 ? 103 LYS L CD 1 ATOM 3869 C CE . LYS B 2 103 ? 38.527 33.118 93.862 1.00 37.13 ? 103 LYS L CE 1 ATOM 3870 N NZ . LYS B 2 103 ? 37.448 34.007 93.487 1.00 40.02 ? 103 LYS L NZ 1 ATOM 3871 N N . LEU B 2 104 ? 36.628 30.243 97.442 1.00 19.91 ? 104 LEU L N 1 ATOM 3872 C CA . LEU B 2 104 ? 35.273 30.417 97.996 1.00 17.90 ? 104 LEU L CA 1 ATOM 3873 C C . LEU B 2 104 ? 34.516 31.566 97.328 1.00 19.18 ? 104 LEU L C 1 ATOM 3874 O O . LEU B 2 104 ? 34.846 32.712 97.659 1.00 21.79 ? 104 LEU L O 1 ATOM 3875 C CB . LEU B 2 104 ? 35.377 30.680 99.510 1.00 17.29 ? 104 LEU L CB 1 ATOM 3876 C CG . LEU B 2 104 ? 34.146 31.071 100.330 1.00 17.44 ? 104 LEU L CG 1 ATOM 3877 C CD1 . LEU B 2 104 ? 33.098 29.948 100.337 1.00 16.06 ? 104 LEU L CD1 1 ATOM 3878 C CD2 . LEU B 2 104 ? 34.607 31.368 101.726 1.00 14.35 ? 104 LEU L CD2 1 ATOM 3879 N N . GLU B 2 105 ? 33.597 31.303 96.366 1.00 19.05 ? 105 GLU L N 1 ATOM 3880 C CA . GLU B 2 105 ? 32.709 32.282 95.730 1.00 19.31 ? 105 GLU L CA 1 ATOM 3881 C C . GLU B 2 105 ? 31.531 32.571 96.665 1.00 20.21 ? 105 GLU L C 1 ATOM 3882 O O . GLU B 2 105 ? 31.022 31.675 97.353 1.00 19.89 ? 105 GLU L O 1 ATOM 3883 C CB . GLU B 2 105 ? 32.135 31.752 94.423 1.00 19.13 ? 105 GLU L CB 1 ATOM 3884 C CG . GLU B 2 105 ? 31.302 32.773 93.654 1.00 18.83 ? 105 GLU L CG 1 ATOM 3885 C CD . GLU B 2 105 ? 30.097 32.228 92.907 1.00 18.66 ? 105 GLU L CD 1 ATOM 3886 O OE1 . GLU B 2 105 ? 29.031 32.114 93.514 1.00 18.53 ? 105 GLU L OE1 1 ATOM 3887 O OE2 . GLU B 2 105 ? 30.214 31.942 91.717 1.00 18.51 ? 105 GLU L OE2 1 ATOM 3888 N N . ILE B 2 106 ? 31.040 33.810 96.673 1.00 21.18 ? 106 ILE L N 1 ATOM 3889 C CA . ILE B 2 106 ? 29.905 34.200 97.494 1.00 22.20 ? 106 ILE L CA 1 ATOM 3890 C C . ILE B 2 106 ? 28.715 34.323 96.551 1.00 22.91 ? 106 ILE L C 1 ATOM 3891 O O . ILE B 2 106 ? 28.798 34.996 95.524 1.00 22.54 ? 106 ILE L O 1 ATOM 3892 C CB . ILE B 2 106 ? 30.232 35.524 98.170 1.00 22.75 ? 106 ILE L CB 1 ATOM 3893 C CG1 . ILE B 2 106 ? 31.543 35.414 98.966 1.00 24.83 ? 106 ILE L CG1 1 ATOM 3894 C CG2 . ILE B 2 106 ? 29.064 35.904 99.054 1.00 23.40 ? 106 ILE L CG2 1 ATOM 3895 C CD1 . ILE B 2 106 ? 31.453 34.631 100.291 1.00 25.76 ? 106 ILE L CD1 1 ATOM 3896 N N . LYS B 2 107 ? 27.605 33.705 96.940 1.00 23.60 ? 107 LYS L N 1 ATOM 3897 C CA . LYS B 2 107 ? 26.418 33.525 96.129 1.00 23.54 ? 107 LYS L CA 1 ATOM 3898 C C . LYS B 2 107 ? 25.261 34.437 96.502 1.00 25.21 ? 107 LYS L C 1 ATOM 3899 O O . LYS B 2 107 ? 24.393 34.244 97.377 1.00 25.70 ? 107 LYS L O 1 ATOM 3900 C CB . LYS B 2 107 ? 26.031 32.062 96.226 1.00 23.83 ? 107 LYS L CB 1 ATOM 3901 C CG . LYS B 2 107 ? 25.089 31.600 95.137 1.00 23.10 ? 107 LYS L CG 1 ATOM 3902 C CD . LYS B 2 107 ? 25.245 30.099 95.019 1.00 22.67 ? 107 LYS L CD 1 ATOM 3903 C CE . LYS B 2 107 ? 24.256 29.574 94.003 1.00 22.43 ? 107 LYS L CE 1 ATOM 3904 N NZ . LYS B 2 107 ? 24.213 28.130 94.067 1.00 22.30 ? 107 LYS L NZ 1 ATOM 3905 N N . ARG B 2 108 ? 25.482 35.517 95.765 1.00 29.28 ? 108 ARG L N 1 ATOM 3906 C CA . ARG B 2 108 ? 24.649 36.698 95.691 1.00 30.81 ? 108 ARG L CA 1 ATOM 3907 C C . ARG B 2 108 ? 23.479 36.326 94.789 1.00 31.19 ? 108 ARG L C 1 ATOM 3908 O O . ARG B 2 108 ? 23.431 35.301 94.106 1.00 31.14 ? 108 ARG L O 1 ATOM 3909 C CB . ARG B 2 108 ? 25.458 37.851 95.068 1.00 32.27 ? 108 ARG L CB 1 ATOM 3910 C CG . ARG B 2 108 ? 24.794 39.202 95.108 1.00 33.30 ? 108 ARG L CG 1 ATOM 3911 C CD . ARG B 2 108 ? 25.197 40.132 93.991 1.00 34.36 ? 108 ARG L CD 1 ATOM 3912 N NE . ARG B 2 108 ? 23.962 40.782 93.605 1.00 38.06 ? 108 ARG L NE 1 ATOM 3913 C CZ . ARG B 2 108 ? 23.653 42.050 93.881 1.00 40.47 ? 108 ARG L CZ 1 ATOM 3914 N NH1 . ARG B 2 108 ? 24.473 42.836 94.574 1.00 41.99 ? 108 ARG L NH1 1 ATOM 3915 N NH2 . ARG B 2 108 ? 22.467 42.543 93.489 1.00 42.67 ? 108 ARG L NH2 1 ATOM 3916 N N . ALA B 2 109 ? 22.494 37.190 94.804 1.00 31.34 ? 109 ALA L N 1 ATOM 3917 C CA . ALA B 2 109 ? 21.381 37.059 93.891 1.00 32.41 ? 109 ALA L CA 1 ATOM 3918 C C . ALA B 2 109 ? 21.804 37.751 92.584 1.00 31.36 ? 109 ALA L C 1 ATOM 3919 O O . ALA B 2 109 ? 22.819 38.445 92.597 1.00 31.76 ? 109 ALA L O 1 ATOM 3920 C CB . ALA B 2 109 ? 20.163 37.749 94.494 1.00 31.64 ? 109 ALA L CB 1 ATOM 3921 N N . ASP B 2 110 ? 21.099 37.610 91.460 1.00 31.13 ? 110 ASP L N 1 ATOM 3922 C CA . ASP B 2 110 ? 21.547 38.205 90.208 1.00 33.05 ? 110 ASP L CA 1 ATOM 3923 C C . ASP B 2 110 ? 21.560 39.726 90.156 1.00 34.14 ? 110 ASP L C 1 ATOM 3924 O O . ASP B 2 110 ? 20.793 40.418 90.833 1.00 34.78 ? 110 ASP L O 1 ATOM 3925 C CB . ASP B 2 110 ? 20.688 37.764 89.010 1.00 31.21 ? 110 ASP L CB 1 ATOM 3926 C CG . ASP B 2 110 ? 20.390 36.282 88.878 1.00 32.19 ? 110 ASP L CG 1 ATOM 3927 O OD1 . ASP B 2 110 ? 21.233 35.443 89.231 1.00 33.73 ? 110 ASP L OD1 1 ATOM 3928 O OD2 . ASP B 2 110 ? 19.273 35.980 88.434 1.00 33.24 ? 110 ASP L OD2 1 ATOM 3929 N N . ALA B 2 111 ? 22.408 40.196 89.234 1.00 35.18 ? 111 ALA L N 1 ATOM 3930 C CA . ALA B 2 111 ? 22.545 41.592 88.856 1.00 35.85 ? 111 ALA L CA 1 ATOM 3931 C C . ALA B 2 111 ? 22.607 41.620 87.314 1.00 35.45 ? 111 ALA L C 1 ATOM 3932 O O . ALA B 2 111 ? 22.706 40.564 86.669 1.00 38.64 ? 111 ALA L O 1 ATOM 3933 C CB . ALA B 2 111 ? 23.840 42.158 89.450 1.00 35.45 ? 111 ALA L CB 1 ATOM 3934 N N . ALA B 2 112 ? 22.588 42.769 86.639 1.00 33.29 ? 112 ALA L N 1 ATOM 3935 C CA . ALA B 2 112 ? 22.658 42.815 85.187 1.00 30.92 ? 112 ALA L CA 1 ATOM 3936 C C . ALA B 2 112 ? 23.696 43.872 84.833 1.00 29.28 ? 112 ALA L C 1 ATOM 3937 O O . ALA B 2 112 ? 23.786 44.873 85.541 1.00 29.50 ? 112 ALA L O 1 ATOM 3938 C CB . ALA B 2 112 ? 21.333 43.226 84.577 1.00 30.96 ? 112 ALA L CB 1 ATOM 3939 N N . PRO B 2 113 ? 24.516 43.693 83.796 1.00 28.14 ? 113 PRO L N 1 ATOM 3940 C CA . PRO B 2 113 ? 25.718 44.465 83.581 1.00 25.45 ? 113 PRO L CA 1 ATOM 3941 C C . PRO B 2 113 ? 25.410 45.874 83.130 1.00 24.62 ? 113 PRO L C 1 ATOM 3942 O O . PRO B 2 113 ? 24.579 46.123 82.255 1.00 24.22 ? 113 PRO L O 1 ATOM 3943 C CB . PRO B 2 113 ? 26.488 43.681 82.548 1.00 25.35 ? 113 PRO L CB 1 ATOM 3944 C CG . PRO B 2 113 ? 25.719 42.391 82.362 1.00 26.02 ? 113 PRO L CG 1 ATOM 3945 C CD . PRO B 2 113 ? 24.305 42.747 82.700 1.00 27.08 ? 113 PRO L CD 1 ATOM 3946 N N . THR B 2 114 ? 26.045 46.862 83.712 1.00 24.12 ? 114 THR L N 1 ATOM 3947 C CA . THR B 2 114 ? 25.960 48.224 83.200 1.00 22.02 ? 114 THR L CA 1 ATOM 3948 C C . THR B 2 114 ? 27.023 48.270 82.081 1.00 20.34 ? 114 THR L C 1 ATOM 3949 O O . THR B 2 114 ? 28.222 48.462 82.317 1.00 18.34 ? 114 THR L O 1 ATOM 3950 C CB . THR B 2 114 ? 26.219 49.138 84.443 1.00 21.41 ? 114 THR L CB 1 ATOM 3951 O OG1 . THR B 2 114 ? 25.214 48.831 85.437 1.00 22.62 ? 114 THR L OG1 1 ATOM 3952 C CG2 . THR B 2 114 ? 26.255 50.607 84.051 1.00 21.92 ? 114 THR L CG2 1 ATOM 3953 N N . VAL B 2 115 ? 26.602 47.831 80.896 1.00 18.69 ? 115 VAL L N 1 ATOM 3954 C CA . VAL B 2 115 ? 27.400 47.774 79.664 1.00 18.92 ? 115 VAL L CA 1 ATOM 3955 C C . VAL B 2 115 ? 27.653 49.202 79.172 1.00 19.45 ? 115 VAL L C 1 ATOM 3956 O O . VAL B 2 115 ? 26.754 50.036 79.337 1.00 19.11 ? 115 VAL L O 1 ATOM 3957 C CB . VAL B 2 115 ? 26.597 46.946 78.627 1.00 18.46 ? 115 VAL L CB 1 ATOM 3958 C CG1 . VAL B 2 115 ? 27.277 47.016 77.290 1.00 18.99 ? 115 VAL L CG1 1 ATOM 3959 C CG2 . VAL B 2 115 ? 26.443 45.510 79.117 1.00 16.09 ? 115 VAL L CG2 1 ATOM 3960 N N . SER B 2 116 ? 28.811 49.556 78.604 1.00 21.44 ? 116 SER L N 1 ATOM 3961 C CA . SER B 2 116 ? 29.043 50.898 78.078 1.00 23.64 ? 116 SER L CA 1 ATOM 3962 C C . SER B 2 116 ? 30.210 50.874 77.105 1.00 24.45 ? 116 SER L C 1 ATOM 3963 O O . SER B 2 116 ? 31.277 50.373 77.448 1.00 26.71 ? 116 SER L O 1 ATOM 3964 C CB . SER B 2 116 ? 29.336 51.878 79.207 1.00 23.71 ? 116 SER L CB 1 ATOM 3965 O OG . SER B 2 116 ? 29.784 51.277 80.410 1.00 26.66 ? 116 SER L OG 1 ATOM 3966 N N . ILE B 2 117 ? 30.021 51.382 75.874 1.00 26.11 ? 117 ILE L N 1 ATOM 3967 C CA . ILE B 2 117 ? 31.011 51.320 74.799 1.00 25.74 ? 117 ILE L CA 1 ATOM 3968 C C . ILE B 2 117 ? 31.714 52.662 74.669 1.00 25.67 ? 117 ILE L C 1 ATOM 3969 O O . ILE B 2 117 ? 31.129 53.714 74.958 1.00 25.73 ? 117 ILE L O 1 ATOM 3970 C CB . ILE B 2 117 ? 30.203 50.868 73.533 1.00 24.92 ? 117 ILE L CB 1 ATOM 3971 C CG1 . ILE B 2 117 ? 31.182 50.320 72.529 1.00 25.49 ? 117 ILE L CG1 1 ATOM 3972 C CG2 . ILE B 2 117 ? 29.363 52.012 72.936 1.00 25.78 ? 117 ILE L CG2 1 ATOM 3973 C CD1 . ILE B 2 117 ? 30.362 49.497 71.524 1.00 25.65 ? 117 ILE L CD1 1 ATOM 3974 N N . PHE B 2 118 ? 32.973 52.626 74.276 1.00 26.05 ? 118 PHE L N 1 ATOM 3975 C CA . PHE B 2 118 ? 33.799 53.806 74.103 1.00 27.00 ? 118 PHE L CA 1 ATOM 3976 C C . PHE B 2 118 ? 34.463 53.757 72.715 1.00 28.98 ? 118 PHE L C 1 ATOM 3977 O O . PHE B 2 118 ? 35.219 52.811 72.423 1.00 29.08 ? 118 PHE L O 1 ATOM 3978 C CB . PHE B 2 118 ? 34.874 53.850 75.208 1.00 27.02 ? 118 PHE L CB 1 ATOM 3979 C CG . PHE B 2 118 ? 34.292 54.021 76.601 1.00 27.15 ? 118 PHE L CG 1 ATOM 3980 C CD1 . PHE B 2 118 ? 33.762 52.925 77.249 1.00 26.09 ? 118 PHE L CD1 1 ATOM 3981 C CD2 . PHE B 2 118 ? 34.225 55.279 77.169 1.00 28.27 ? 118 PHE L CD2 1 ATOM 3982 C CE1 . PHE B 2 118 ? 33.150 53.089 78.463 1.00 25.16 ? 118 PHE L CE1 1 ATOM 3983 C CE2 . PHE B 2 118 ? 33.609 55.434 78.385 1.00 27.68 ? 118 PHE L CE2 1 ATOM 3984 C CZ . PHE B 2 118 ? 33.071 54.336 79.027 1.00 26.22 ? 118 PHE L CZ 1 ATOM 3985 N N . PRO B 2 119 ? 34.168 54.696 71.791 1.00 29.97 ? 119 PRO L N 1 ATOM 3986 C CA . PRO B 2 119 ? 35.076 55.157 70.732 1.00 29.09 ? 119 PRO L CA 1 ATOM 3987 C C . PRO B 2 119 ? 36.552 55.340 71.089 1.00 29.72 ? 119 PRO L C 1 ATOM 3988 O O . PRO B 2 119 ? 36.900 55.509 72.271 1.00 32.24 ? 119 PRO L O 1 ATOM 3989 C CB . PRO B 2 119 ? 34.463 56.448 70.246 1.00 28.73 ? 119 PRO L CB 1 ATOM 3990 C CG . PRO B 2 119 ? 33.415 56.759 71.297 1.00 28.67 ? 119 PRO L CG 1 ATOM 3991 C CD . PRO B 2 119 ? 32.896 55.373 71.670 1.00 28.89 ? 119 PRO L CD 1 ATOM 3992 N N . PRO B 2 120 ? 37.444 55.293 70.079 1.00 29.18 ? 120 PRO L N 1 ATOM 3993 C CA . PRO B 2 120 ? 38.857 55.612 70.215 1.00 29.53 ? 120 PRO L CA 1 ATOM 3994 C C . PRO B 2 120 ? 39.099 56.984 70.818 1.00 30.10 ? 120 PRO L C 1 ATOM 3995 O O . PRO B 2 120 ? 38.269 57.892 70.667 1.00 31.16 ? 120 PRO L O 1 ATOM 3996 C CB . PRO B 2 120 ? 39.395 55.484 68.820 1.00 28.93 ? 120 PRO L CB 1 ATOM 3997 C CG . PRO B 2 120 ? 38.602 54.327 68.306 1.00 29.43 ? 120 PRO L CG 1 ATOM 3998 C CD . PRO B 2 120 ? 37.202 54.715 68.765 1.00 29.52 ? 120 PRO L CD 1 ATOM 3999 N N . SER B 2 121 ? 40.183 57.177 71.563 1.00 30.52 ? 121 SER L N 1 ATOM 4000 C CA . SER B 2 121 ? 40.520 58.525 71.953 1.00 30.90 ? 121 SER L CA 1 ATOM 4001 C C . SER B 2 121 ? 41.021 59.108 70.633 1.00 32.06 ? 121 SER L C 1 ATOM 4002 O O . SER B 2 121 ? 41.593 58.411 69.783 1.00 32.81 ? 121 SER L O 1 ATOM 4003 C CB . SER B 2 121 ? 41.625 58.540 73.037 1.00 31.22 ? 121 SER L CB 1 ATOM 4004 O OG . SER B 2 121 ? 42.951 58.173 72.654 1.00 32.86 ? 121 SER L OG 1 ATOM 4005 N N . SER B 2 122 ? 40.776 60.378 70.386 1.00 34.55 ? 122 SER L N 1 ATOM 4006 C CA . SER B 2 122 ? 41.258 61.032 69.182 1.00 36.85 ? 122 SER L CA 1 ATOM 4007 C C . SER B 2 122 ? 42.786 60.855 69.116 1.00 35.48 ? 122 SER L C 1 ATOM 4008 O O . SER B 2 122 ? 43.336 60.432 68.090 1.00 36.40 ? 122 SER L O 1 ATOM 4009 C CB . SER B 2 122 ? 40.810 62.490 69.286 1.00 38.14 ? 122 SER L CB 1 ATOM 4010 O OG . SER B 2 122 ? 39.511 62.546 69.903 1.00 40.88 ? 122 SER L OG 1 ATOM 4011 N N . GLU B 2 123 ? 43.362 60.987 70.329 1.00 34.40 ? 123 GLU L N 1 ATOM 4012 C CA . GLU B 2 123 ? 44.775 60.814 70.636 1.00 34.73 ? 123 GLU L CA 1 ATOM 4013 C C . GLU B 2 123 ? 45.332 59.535 70.027 1.00 31.30 ? 123 GLU L C 1 ATOM 4014 O O . GLU B 2 123 ? 46.403 59.534 69.431 1.00 30.80 ? 123 GLU L O 1 ATOM 4015 C CB . GLU B 2 123 ? 45.058 60.677 72.129 1.00 37.33 ? 123 GLU L CB 1 ATOM 4016 C CG . GLU B 2 123 ? 44.129 61.288 73.195 1.00 39.84 ? 123 GLU L CG 1 ATOM 4017 C CD . GLU B 2 123 ? 44.137 62.814 73.316 1.00 42.86 ? 123 GLU L CD 1 ATOM 4018 O OE1 . GLU B 2 123 ? 45.047 63.355 73.972 1.00 43.53 ? 123 GLU L OE1 1 ATOM 4019 O OE2 . GLU B 2 123 ? 43.219 63.444 72.768 1.00 43.88 ? 123 GLU L OE2 1 ATOM 4020 N N . GLN B 2 124 ? 44.602 58.424 70.163 1.00 28.22 ? 124 GLN L N 1 ATOM 4021 C CA . GLN B 2 124 ? 45.035 57.119 69.692 1.00 26.59 ? 124 GLN L CA 1 ATOM 4022 C C . GLN B 2 124 ? 44.949 57.026 68.194 1.00 26.19 ? 124 GLN L C 1 ATOM 4023 O O . GLN B 2 124 ? 45.809 56.405 67.539 1.00 26.54 ? 124 GLN L O 1 ATOM 4024 C CB . GLN B 2 124 ? 44.168 56.027 70.277 1.00 24.27 ? 124 GLN L CB 1 ATOM 4025 C CG . GLN B 2 124 ? 44.664 54.626 69.977 1.00 20.43 ? 124 GLN L CG 1 ATOM 4026 C CD . GLN B 2 124 ? 43.724 53.544 70.466 1.00 18.71 ? 124 GLN L CD 1 ATOM 4027 O OE1 . GLN B 2 124 ? 42.545 53.775 70.773 1.00 15.63 ? 124 GLN L OE1 1 ATOM 4028 N NE2 . GLN B 2 124 ? 44.194 52.300 70.530 1.00 19.35 ? 124 GLN L NE2 1 ATOM 4029 N N . LEU B 2 125 ? 43.883 57.647 67.676 1.00 27.46 ? 125 LEU L N 1 ATOM 4030 C CA . LEU B 2 125 ? 43.659 57.649 66.249 1.00 28.68 ? 125 LEU L CA 1 ATOM 4031 C C . LEU B 2 125 ? 44.801 58.393 65.628 1.00 29.91 ? 125 LEU L C 1 ATOM 4032 O O . LEU B 2 125 ? 45.302 57.921 64.617 1.00 30.47 ? 125 LEU L O 1 ATOM 4033 C CB . LEU B 2 125 ? 42.341 58.317 65.913 1.00 28.79 ? 125 LEU L CB 1 ATOM 4034 C CG . LEU B 2 125 ? 41.077 57.450 66.076 1.00 30.11 ? 125 LEU L CG 1 ATOM 4035 C CD1 . LEU B 2 125 ? 39.863 58.362 66.063 1.00 30.54 ? 125 LEU L CD1 1 ATOM 4036 C CD2 . LEU B 2 125 ? 40.969 56.411 64.961 1.00 29.19 ? 125 LEU L CD2 1 ATOM 4037 N N . THR B 2 126 ? 45.294 59.444 66.281 1.00 30.85 ? 126 THR L N 1 ATOM 4038 C CA . THR B 2 126 ? 46.460 60.176 65.829 1.00 32.16 ? 126 THR L CA 1 ATOM 4039 C C . THR B 2 126 ? 47.657 59.220 65.822 1.00 32.97 ? 126 THR L C 1 ATOM 4040 O O . THR B 2 126 ? 48.470 59.273 64.899 1.00 34.32 ? 126 THR L O 1 ATOM 4041 C CB . THR B 2 126 ? 46.701 61.393 66.774 1.00 32.70 ? 126 THR L CB 1 ATOM 4042 O OG1 . THR B 2 126 ? 45.504 62.197 66.712 1.00 32.41 ? 126 THR L OG1 1 ATOM 4043 C CG2 . THR B 2 126 ? 47.928 62.235 66.399 1.00 33.02 ? 126 THR L CG2 1 ATOM 4044 N N . SER B 2 127 ? 47.815 58.317 66.788 1.00 34.55 ? 127 SER L N 1 ATOM 4045 C CA . SER B 2 127 ? 48.855 57.291 66.745 1.00 35.55 ? 127 SER L CA 1 ATOM 4046 C C . SER B 2 127 ? 48.667 56.196 65.661 1.00 34.62 ? 127 SER L C 1 ATOM 4047 O O . SER B 2 127 ? 49.511 55.288 65.488 1.00 35.17 ? 127 SER L O 1 ATOM 4048 C CB . SER B 2 127 ? 48.912 56.680 68.138 1.00 35.99 ? 127 SER L CB 1 ATOM 4049 O OG . SER B 2 127 ? 49.060 57.731 69.083 1.00 39.00 ? 127 SER L OG 1 ATOM 4050 N N . GLY B 2 128 ? 47.524 56.228 64.960 1.00 31.84 ? 128 GLY L N 1 ATOM 4051 C CA . GLY B 2 128 ? 47.281 55.315 63.872 1.00 30.61 ? 128 GLY L CA 1 ATOM 4052 C C . GLY B 2 128 ? 46.703 53.994 64.369 1.00 30.48 ? 128 GLY L C 1 ATOM 4053 O O . GLY B 2 128 ? 46.566 53.047 63.569 1.00 32.41 ? 128 GLY L O 1 ATOM 4054 N N . GLY B 2 129 ? 46.281 53.909 65.648 1.00 28.39 ? 129 GLY L N 1 ATOM 4055 C CA . GLY B 2 129 ? 45.625 52.718 66.169 1.00 25.80 ? 129 GLY L CA 1 ATOM 4056 C C . GLY B 2 129 ? 44.197 53.052 66.614 1.00 24.67 ? 129 GLY L C 1 ATOM 4057 O O . GLY B 2 129 ? 43.900 54.220 66.925 1.00 24.61 ? 129 GLY L O 1 ATOM 4058 N N . ALA B 2 130 ? 43.288 52.070 66.689 1.00 22.32 ? 130 ALA L N 1 ATOM 4059 C CA . ALA B 2 130 ? 41.942 52.338 67.138 1.00 21.65 ? 130 ALA L CA 1 ATOM 4060 C C . ALA B 2 130 ? 41.429 51.241 68.025 1.00 21.92 ? 130 ALA L C 1 ATOM 4061 O O . ALA B 2 130 ? 41.037 50.191 67.525 1.00 20.72 ? 130 ALA L O 1 ATOM 4062 C CB . ALA B 2 130 ? 40.981 52.454 65.970 1.00 21.09 ? 130 ALA L CB 1 ATOM 4063 N N . SER B 2 131 ? 41.463 51.450 69.337 1.00 23.31 ? 131 SER L N 1 ATOM 4064 C CA . SER B 2 131 ? 40.817 50.524 70.265 1.00 22.78 ? 131 SER L CA 1 ATOM 4065 C C . SER B 2 131 ? 39.420 51.079 70.626 1.00 23.92 ? 131 SER L C 1 ATOM 4066 O O . SER B 2 131 ? 39.218 52.295 70.758 1.00 22.95 ? 131 SER L O 1 ATOM 4067 C CB . SER B 2 131 ? 41.653 50.346 71.546 1.00 20.90 ? 131 SER L CB 1 ATOM 4068 O OG . SER B 2 131 ? 42.973 49.917 71.248 1.00 18.59 ? 131 SER L OG 1 ATOM 4069 N N . VAL B 2 132 ? 38.455 50.164 70.744 1.00 23.99 ? 132 VAL L N 1 ATOM 4070 C CA . VAL B 2 132 ? 37.077 50.433 71.058 1.00 25.58 ? 132 VAL L CA 1 ATOM 4071 C C . VAL B 2 132 ? 36.919 49.610 72.359 1.00 25.75 ? 132 VAL L C 1 ATOM 4072 O O . VAL B 2 132 ? 37.029 48.368 72.372 1.00 26.22 ? 132 VAL L O 1 ATOM 4073 C CB . VAL B 2 132 ? 36.190 49.890 69.895 1.00 26.65 ? 132 VAL L CB 1 ATOM 4074 C CG1 . VAL B 2 132 ? 34.776 50.450 69.985 1.00 26.99 ? 132 VAL L CG1 1 ATOM 4075 C CG2 . VAL B 2 132 ? 36.759 50.313 68.548 1.00 27.33 ? 132 VAL L CG2 1 ATOM 4076 N N . VAL B 2 133 ? 36.770 50.308 73.493 1.00 24.25 ? 133 VAL L N 1 ATOM 4077 C CA . VAL B 2 133 ? 36.580 49.674 74.799 1.00 22.47 ? 133 VAL L CA 1 ATOM 4078 C C . VAL B 2 133 ? 35.086 49.501 75.176 1.00 22.50 ? 133 VAL L C 1 ATOM 4079 O O . VAL B 2 133 ? 34.258 50.392 74.999 1.00 20.23 ? 133 VAL L O 1 ATOM 4080 C CB . VAL B 2 133 ? 37.332 50.540 75.848 1.00 22.66 ? 133 VAL L CB 1 ATOM 4081 C CG1 . VAL B 2 133 ? 37.237 49.922 77.224 1.00 21.49 ? 133 VAL L CG1 1 ATOM 4082 C CG2 . VAL B 2 133 ? 38.786 50.629 75.481 1.00 22.56 ? 133 VAL L CG2 1 ATOM 4083 N N . CYS B 2 134 ? 34.649 48.357 75.666 1.00 23.36 ? 134 CYS L N 1 ATOM 4084 C CA . CYS B 2 134 ? 33.300 48.171 76.157 1.00 22.48 ? 134 CYS L CA 1 ATOM 4085 C C . CYS B 2 134 ? 33.442 47.682 77.597 1.00 21.29 ? 134 CYS L C 1 ATOM 4086 O O . CYS B 2 134 ? 34.081 46.636 77.783 1.00 21.11 ? 134 CYS L O 1 ATOM 4087 C CB . CYS B 2 134 ? 32.615 47.124 75.324 1.00 25.77 ? 134 CYS L CB 1 ATOM 4088 S SG . CYS B 2 134 ? 30.938 46.746 75.882 1.00 31.83 ? 134 CYS L SG 1 ATOM 4089 N N . PHE B 2 135 ? 32.992 48.376 78.655 1.00 17.66 ? 135 PHE L N 1 ATOM 4090 C CA . PHE B 2 135 ? 33.010 47.849 80.013 1.00 13.42 ? 135 PHE L CA 1 ATOM 4091 C C . PHE B 2 135 ? 31.660 47.193 80.251 1.00 13.18 ? 135 PHE L C 1 ATOM 4092 O O . PHE B 2 135 ? 30.646 47.615 79.665 1.00 11.66 ? 135 PHE L O 1 ATOM 4093 C CB . PHE B 2 135 ? 33.116 48.921 81.023 1.00 12.57 ? 135 PHE L CB 1 ATOM 4094 C CG . PHE B 2 135 ? 34.375 49.728 80.939 1.00 10.58 ? 135 PHE L CG 1 ATOM 4095 C CD1 . PHE B 2 135 ? 35.599 49.147 81.173 1.00 8.21 ? 135 PHE L CD1 1 ATOM 4096 C CD2 . PHE B 2 135 ? 34.283 51.058 80.668 1.00 9.78 ? 135 PHE L CD2 1 ATOM 4097 C CE1 . PHE B 2 135 ? 36.741 49.904 81.144 1.00 8.37 ? 135 PHE L CE1 1 ATOM 4098 C CE2 . PHE B 2 135 ? 35.433 51.818 80.645 1.00 7.84 ? 135 PHE L CE2 1 ATOM 4099 C CZ . PHE B 2 135 ? 36.652 51.246 80.880 1.00 8.60 ? 135 PHE L CZ 1 ATOM 4100 N N . LEU B 2 136 ? 31.569 46.141 81.063 1.00 12.69 ? 136 LEU L N 1 ATOM 4101 C CA . LEU B 2 136 ? 30.282 45.549 81.454 1.00 14.27 ? 136 LEU L CA 1 ATOM 4102 C C . LEU B 2 136 ? 30.327 45.431 82.982 1.00 15.42 ? 136 LEU L C 1 ATOM 4103 O O . LEU B 2 136 ? 30.849 44.458 83.571 1.00 17.14 ? 136 LEU L O 1 ATOM 4104 C CB . LEU B 2 136 ? 30.107 44.172 80.922 1.00 15.36 ? 136 LEU L CB 1 ATOM 4105 C CG . LEU B 2 136 ? 29.921 43.883 79.473 1.00 16.65 ? 136 LEU L CG 1 ATOM 4106 C CD1 . LEU B 2 136 ? 31.077 44.348 78.620 1.00 17.33 ? 136 LEU L CD1 1 ATOM 4107 C CD2 . LEU B 2 136 ? 29.802 42.370 79.368 1.00 16.41 ? 136 LEU L CD2 1 ATOM 4108 N N . ASN B 2 137 ? 29.764 46.431 83.661 1.00 13.89 ? 137 ASN L N 1 ATOM 4109 C CA . ASN B 2 137 ? 30.016 46.547 85.075 1.00 13.42 ? 137 ASN L CA 1 ATOM 4110 C C . ASN B 2 137 ? 28.929 46.058 85.971 1.00 15.12 ? 137 ASN L C 1 ATOM 4111 O O . ASN B 2 137 ? 27.757 46.412 85.805 1.00 16.05 ? 137 ASN L O 1 ATOM 4112 C CB . ASN B 2 137 ? 30.326 48.002 85.441 1.00 9.06 ? 137 ASN L CB 1 ATOM 4113 C CG . ASN B 2 137 ? 31.675 48.364 84.876 1.00 5.40 ? 137 ASN L CG 1 ATOM 4114 O OD1 . ASN B 2 137 ? 31.838 49.232 84.029 1.00 3.14 ? 137 ASN L OD1 1 ATOM 4115 N ND2 . ASN B 2 137 ? 32.710 47.661 85.278 1.00 5.35 ? 137 ASN L ND2 1 ATOM 4116 N N . ASN B 2 138 ? 29.416 45.295 86.956 1.00 17.74 ? 138 ASN L N 1 ATOM 4117 C CA . ASN B 2 138 ? 28.664 44.754 88.093 1.00 18.67 ? 138 ASN L CA 1 ATOM 4118 C C . ASN B 2 138 ? 27.520 43.768 87.859 1.00 20.30 ? 138 ASN L C 1 ATOM 4119 O O . ASN B 2 138 ? 26.365 43.973 88.270 1.00 22.50 ? 138 ASN L O 1 ATOM 4120 C CB . ASN B 2 138 ? 28.079 45.870 88.968 1.00 19.27 ? 138 ASN L CB 1 ATOM 4121 C CG . ASN B 2 138 ? 28.773 47.222 88.878 1.00 21.87 ? 138 ASN L CG 1 ATOM 4122 O OD1 . ASN B 2 138 ? 29.866 47.475 89.419 1.00 22.44 ? 138 ASN L OD1 1 ATOM 4123 N ND2 . ASN B 2 138 ? 28.118 48.107 88.099 1.00 23.65 ? 138 ASN L ND2 1 ATOM 4124 N N . PHE B 2 139 ? 27.843 42.593 87.303 1.00 20.57 ? 139 PHE L N 1 ATOM 4125 C CA . PHE B 2 139 ? 26.871 41.548 87.009 1.00 17.57 ? 139 PHE L CA 1 ATOM 4126 C C . PHE B 2 139 ? 27.130 40.319 87.847 1.00 17.56 ? 139 PHE L C 1 ATOM 4127 O O . PHE B 2 139 ? 28.229 40.043 88.369 1.00 19.91 ? 139 PHE L O 1 ATOM 4128 C CB . PHE B 2 139 ? 26.915 41.153 85.536 1.00 17.92 ? 139 PHE L CB 1 ATOM 4129 C CG . PHE B 2 139 ? 28.276 40.724 84.989 1.00 18.89 ? 139 PHE L CG 1 ATOM 4130 C CD1 . PHE B 2 139 ? 29.280 41.650 84.811 1.00 20.68 ? 139 PHE L CD1 1 ATOM 4131 C CD2 . PHE B 2 139 ? 28.516 39.394 84.768 1.00 20.04 ? 139 PHE L CD2 1 ATOM 4132 C CE1 . PHE B 2 139 ? 30.527 41.250 84.426 1.00 22.45 ? 139 PHE L CE1 1 ATOM 4133 C CE2 . PHE B 2 139 ? 29.763 38.998 84.380 1.00 22.33 ? 139 PHE L CE2 1 ATOM 4134 C CZ . PHE B 2 139 ? 30.774 39.921 84.215 1.00 23.34 ? 139 PHE L CZ 1 ATOM 4135 N N . TYR B 2 140 ? 26.027 39.606 87.991 1.00 17.41 ? 140 TYR L N 1 ATOM 4136 C CA . TYR B 2 140 ? 26.004 38.422 88.810 1.00 18.92 ? 140 TYR L CA 1 ATOM 4137 C C . TYR B 2 140 ? 24.980 37.550 88.129 1.00 19.98 ? 140 TYR L C 1 ATOM 4138 O O . TYR B 2 140 ? 23.866 38.056 88.011 1.00 19.27 ? 140 TYR L O 1 ATOM 4139 C CB . TYR B 2 140 ? 25.515 38.688 90.255 1.00 17.75 ? 140 TYR L CB 1 ATOM 4140 C CG . TYR B 2 140 ? 25.741 37.374 90.959 1.00 20.20 ? 140 TYR L CG 1 ATOM 4141 C CD1 . TYR B 2 140 ? 27.049 37.088 91.272 1.00 20.27 ? 140 TYR L CD1 1 ATOM 4142 C CD2 . TYR B 2 140 ? 24.725 36.429 91.068 1.00 19.71 ? 140 TYR L CD2 1 ATOM 4143 C CE1 . TYR B 2 140 ? 27.362 35.829 91.651 1.00 21.14 ? 140 TYR L CE1 1 ATOM 4144 C CE2 . TYR B 2 140 ? 25.038 35.162 91.454 1.00 19.51 ? 140 TYR L CE2 1 ATOM 4145 C CZ . TYR B 2 140 ? 26.360 34.896 91.723 1.00 20.81 ? 140 TYR L CZ 1 ATOM 4146 O OH . TYR B 2 140 ? 26.761 33.618 92.002 1.00 22.29 ? 140 TYR L OH 1 ATOM 4147 N N . PRO B 2 141 ? 25.167 36.292 87.725 1.00 21.03 ? 141 PRO L N 1 ATOM 4148 C CA . PRO B 2 141 ? 26.402 35.512 87.781 1.00 22.89 ? 141 PRO L CA 1 ATOM 4149 C C . PRO B 2 141 ? 27.646 35.916 86.973 1.00 24.60 ? 141 PRO L C 1 ATOM 4150 O O . PRO B 2 141 ? 27.696 36.932 86.289 1.00 24.10 ? 141 PRO L O 1 ATOM 4151 C CB . PRO B 2 141 ? 25.920 34.132 87.429 1.00 22.27 ? 141 PRO L CB 1 ATOM 4152 C CG . PRO B 2 141 ? 24.498 34.127 87.903 1.00 21.11 ? 141 PRO L CG 1 ATOM 4153 C CD . PRO B 2 141 ? 24.052 35.435 87.360 1.00 20.60 ? 141 PRO L CD 1 ATOM 4154 N N . LYS B 2 142 ? 28.676 35.083 87.073 1.00 28.87 ? 142 LYS L N 1 ATOM 4155 C CA . LYS B 2 142 ? 29.943 35.265 86.380 1.00 32.20 ? 142 LYS L CA 1 ATOM 4156 C C . LYS B 2 142 ? 29.913 34.985 84.867 1.00 34.43 ? 142 LYS L C 1 ATOM 4157 O O . LYS B 2 142 ? 30.795 35.380 84.093 1.00 36.06 ? 142 LYS L O 1 ATOM 4158 C CB . LYS B 2 142 ? 30.925 34.348 87.074 1.00 31.73 ? 142 LYS L CB 1 ATOM 4159 C CG . LYS B 2 142 ? 32.375 34.387 86.665 1.00 33.55 ? 142 LYS L CG 1 ATOM 4160 C CD . LYS B 2 142 ? 32.903 33.182 87.409 1.00 35.79 ? 142 LYS L CD 1 ATOM 4161 C CE . LYS B 2 142 ? 34.406 33.190 87.632 1.00 37.80 ? 142 LYS L CE 1 ATOM 4162 N NZ . LYS B 2 142 ? 34.686 32.402 88.822 1.00 38.56 ? 142 LYS L NZ 1 ATOM 4163 N N . ASP B 2 143 ? 28.905 34.256 84.396 1.00 36.31 ? 143 ASP L N 1 ATOM 4164 C CA . ASP B 2 143 ? 28.883 33.819 83.011 1.00 37.69 ? 143 ASP L CA 1 ATOM 4165 C C . ASP B 2 143 ? 28.260 34.826 82.056 1.00 37.25 ? 143 ASP L C 1 ATOM 4166 O O . ASP B 2 143 ? 27.027 34.910 81.939 1.00 37.85 ? 143 ASP L O 1 ATOM 4167 C CB . ASP B 2 143 ? 28.155 32.459 82.969 1.00 39.98 ? 143 ASP L CB 1 ATOM 4168 C CG . ASP B 2 143 ? 28.882 31.284 83.636 1.00 41.76 ? 143 ASP L CG 1 ATOM 4169 O OD1 . ASP B 2 143 ? 30.077 31.352 83.955 1.00 42.60 ? 143 ASP L OD1 1 ATOM 4170 O OD2 . ASP B 2 143 ? 28.224 30.258 83.821 1.00 43.18 ? 143 ASP L OD2 1 ATOM 4171 N N . ILE B 2 144 ? 29.140 35.621 81.433 1.00 35.19 ? 144 ILE L N 1 ATOM 4172 C CA . ILE B 2 144 ? 28.705 36.585 80.444 1.00 32.22 ? 144 ILE L CA 1 ATOM 4173 C C . ILE B 2 144 ? 29.465 36.381 79.140 1.00 32.76 ? 144 ILE L C 1 ATOM 4174 O O . ILE B 2 144 ? 30.700 36.255 79.148 1.00 33.71 ? 144 ILE L O 1 ATOM 4175 C CB . ILE B 2 144 ? 28.921 38.010 80.981 1.00 31.60 ? 144 ILE L CB 1 ATOM 4176 C CG1 . ILE B 2 144 ? 28.044 38.904 80.155 1.00 30.04 ? 144 ILE L CG1 1 ATOM 4177 C CG2 . ILE B 2 144 ? 30.381 38.487 80.908 1.00 31.87 ? 144 ILE L CG2 1 ATOM 4178 C CD1 . ILE B 2 144 ? 27.739 40.166 80.944 1.00 28.70 ? 144 ILE L CD1 1 ATOM 4179 N N . ASN B 2 145 ? 28.779 36.313 77.999 1.00 31.88 ? 145 ASN L N 1 ATOM 4180 C CA . ASN B 2 145 ? 29.490 36.198 76.737 1.00 31.38 ? 145 ASN L CA 1 ATOM 4181 C C . ASN B 2 145 ? 29.457 37.556 76.070 1.00 28.93 ? 145 ASN L C 1 ATOM 4182 O O . ASN B 2 145 ? 28.367 38.138 76.026 1.00 27.87 ? 145 ASN L O 1 ATOM 4183 C CB . ASN B 2 145 ? 28.819 35.186 75.830 1.00 34.03 ? 145 ASN L CB 1 ATOM 4184 C CG . ASN B 2 145 ? 29.471 35.129 74.442 1.00 35.58 ? 145 ASN L CG 1 ATOM 4185 O OD1 . ASN B 2 145 ? 30.358 34.312 74.162 1.00 36.19 ? 145 ASN L OD1 1 ATOM 4186 N ND2 . ASN B 2 145 ? 29.040 35.993 73.524 1.00 36.34 ? 145 ASN L ND2 1 ATOM 4187 N N . VAL B 2 146 ? 30.551 38.135 75.571 1.00 27.86 ? 146 VAL L N 1 ATOM 4188 C CA . VAL B 2 146 ? 30.372 39.388 74.857 1.00 26.94 ? 146 VAL L CA 1 ATOM 4189 C C . VAL B 2 146 ? 30.851 39.154 73.431 1.00 28.16 ? 146 VAL L C 1 ATOM 4190 O O . VAL B 2 146 ? 31.848 38.433 73.286 1.00 30.24 ? 146 VAL L O 1 ATOM 4191 C CB . VAL B 2 146 ? 31.155 40.589 75.512 1.00 24.97 ? 146 VAL L CB 1 ATOM 4192 C CG1 . VAL B 2 146 ? 31.065 40.390 77.003 1.00 24.91 ? 146 VAL L CG1 1 ATOM 4193 C CG2 . VAL B 2 146 ? 32.585 40.716 75.093 1.00 26.33 ? 146 VAL L CG2 1 ATOM 4194 N N . LYS B 2 147 ? 30.151 39.618 72.376 1.00 28.48 ? 147 LYS L N 1 ATOM 4195 C CA . LYS B 2 147 ? 30.615 39.507 71.000 1.00 28.20 ? 147 LYS L CA 1 ATOM 4196 C C . LYS B 2 147 ? 30.811 40.952 70.537 1.00 29.88 ? 147 LYS L C 1 ATOM 4197 O O . LYS B 2 147 ? 30.148 41.881 71.042 1.00 29.70 ? 147 LYS L O 1 ATOM 4198 C CB . LYS B 2 147 ? 29.597 38.834 70.062 1.00 28.13 ? 147 LYS L CB 1 ATOM 4199 C CG . LYS B 2 147 ? 29.528 37.310 70.175 1.00 27.56 ? 147 LYS L CG 1 ATOM 4200 C CD . LYS B 2 147 ? 28.920 36.613 68.953 1.00 27.18 ? 147 LYS L CD 1 ATOM 4201 C CE . LYS B 2 147 ? 27.415 36.796 68.798 1.00 26.90 ? 147 LYS L CE 1 ATOM 4202 N NZ . LYS B 2 147 ? 26.933 36.069 67.637 1.00 26.81 ? 147 LYS L NZ 1 ATOM 4203 N N . TRP B 2 148 ? 31.768 41.204 69.654 1.00 29.40 ? 148 TRP L N 1 ATOM 4204 C CA . TRP B 2 148 ? 31.882 42.508 69.024 1.00 28.76 ? 148 TRP L CA 1 ATOM 4205 C C . TRP B 2 148 ? 31.366 42.250 67.642 1.00 29.33 ? 148 TRP L C 1 ATOM 4206 O O . TRP B 2 148 ? 31.525 41.149 67.093 1.00 30.39 ? 148 TRP L O 1 ATOM 4207 C CB . TRP B 2 148 ? 33.264 42.996 68.834 1.00 27.18 ? 148 TRP L CB 1 ATOM 4208 C CG . TRP B 2 148 ? 33.763 43.538 70.117 1.00 25.72 ? 148 TRP L CG 1 ATOM 4209 C CD1 . TRP B 2 148 ? 34.407 42.739 70.994 1.00 25.91 ? 148 TRP L CD1 1 ATOM 4210 C CD2 . TRP B 2 148 ? 33.730 44.850 70.472 1.00 25.96 ? 148 TRP L CD2 1 ATOM 4211 N NE1 . TRP B 2 148 ? 34.817 43.554 71.922 1.00 26.67 ? 148 TRP L NE1 1 ATOM 4212 C CE2 . TRP B 2 148 ? 34.445 44.822 71.655 1.00 26.26 ? 148 TRP L CE2 1 ATOM 4213 C CE3 . TRP B 2 148 ? 33.227 46.046 69.990 1.00 25.87 ? 148 TRP L CE3 1 ATOM 4214 C CZ2 . TRP B 2 148 ? 34.683 45.990 72.366 1.00 23.40 ? 148 TRP L CZ2 1 ATOM 4215 C CZ3 . TRP B 2 148 ? 33.460 47.208 70.702 1.00 24.11 ? 148 TRP L CZ3 1 ATOM 4216 C CH2 . TRP B 2 148 ? 34.185 47.177 71.877 1.00 23.36 ? 148 TRP L CH2 1 ATOM 4217 N N . LYS B 2 149 ? 30.703 43.271 67.120 1.00 31.61 ? 149 LYS L N 1 ATOM 4218 C CA . LYS B 2 149 ? 30.131 43.255 65.782 1.00 33.03 ? 149 LYS L CA 1 ATOM 4219 C C . LYS B 2 149 ? 30.397 44.597 65.152 1.00 32.91 ? 149 LYS L C 1 ATOM 4220 O O . LYS B 2 149 ? 30.051 45.669 65.675 1.00 33.78 ? 149 LYS L O 1 ATOM 4221 C CB . LYS B 2 149 ? 28.617 43.027 65.780 1.00 32.72 ? 149 LYS L CB 1 ATOM 4222 C CG . LYS B 2 149 ? 28.356 41.600 66.178 1.00 35.59 ? 149 LYS L CG 1 ATOM 4223 C CD . LYS B 2 149 ? 26.893 41.274 66.094 1.00 41.25 ? 149 LYS L CD 1 ATOM 4224 C CE . LYS B 2 149 ? 26.620 40.064 66.995 1.00 44.62 ? 149 LYS L CE 1 ATOM 4225 N NZ . LYS B 2 149 ? 25.210 39.678 67.069 1.00 46.45 ? 149 LYS L NZ 1 ATOM 4226 N N . ILE B 2 150 ? 31.092 44.526 64.041 1.00 32.67 ? 150 ILE L N 1 ATOM 4227 C CA . ILE B 2 150 ? 31.336 45.724 63.265 1.00 31.98 ? 150 ILE L CA 1 ATOM 4228 C C . ILE B 2 150 ? 30.538 45.432 62.019 1.00 31.77 ? 150 ILE L C 1 ATOM 4229 O O . ILE B 2 150 ? 30.656 44.374 61.380 1.00 32.15 ? 150 ILE L O 1 ATOM 4230 C CB . ILE B 2 150 ? 32.763 45.968 62.742 1.00 31.80 ? 150 ILE L CB 1 ATOM 4231 C CG1 . ILE B 2 150 ? 33.853 45.575 63.736 1.00 31.15 ? 150 ILE L CG1 1 ATOM 4232 C CG2 . ILE B 2 150 ? 32.789 47.462 62.385 1.00 30.21 ? 150 ILE L CG2 1 ATOM 4233 C CD1 . ILE B 2 150 ? 35.179 45.182 63.067 1.00 30.77 ? 150 ILE L CD1 1 ATOM 4234 N N . ASP B 2 151 ? 29.666 46.414 61.779 1.00 32.17 ? 151 ASP L N 1 ATOM 4235 C CA . ASP B 2 151 ? 28.815 46.471 60.619 1.00 31.82 ? 151 ASP L CA 1 ATOM 4236 C C . ASP B 2 151 ? 28.056 45.178 60.480 1.00 32.74 ? 151 ASP L C 1 ATOM 4237 O O . ASP B 2 151 ? 28.106 44.487 59.472 1.00 36.11 ? 151 ASP L O 1 ATOM 4238 C CB . ASP B 2 151 ? 29.709 46.787 59.437 1.00 29.31 ? 151 ASP L CB 1 ATOM 4239 C CG . ASP B 2 151 ? 29.773 48.299 59.315 1.00 28.11 ? 151 ASP L CG 1 ATOM 4240 O OD1 . ASP B 2 151 ? 30.467 49.008 60.058 1.00 26.98 ? 151 ASP L OD1 1 ATOM 4241 O OD2 . ASP B 2 151 ? 29.074 48.776 58.435 1.00 27.58 ? 151 ASP L OD2 1 ATOM 4242 N N . GLY B 2 152 ? 27.457 44.766 61.596 1.00 33.88 ? 152 GLY L N 1 ATOM 4243 C CA . GLY B 2 152 ? 26.598 43.593 61.645 1.00 36.23 ? 152 GLY L CA 1 ATOM 4244 C C . GLY B 2 152 ? 27.340 42.296 61.427 1.00 36.99 ? 152 GLY L C 1 ATOM 4245 O O . GLY B 2 152 ? 26.756 41.216 61.442 1.00 37.91 ? 152 GLY L O 1 ATOM 4246 N N . SER B 2 153 ? 28.635 42.374 61.214 1.00 37.19 ? 153 SER L N 1 ATOM 4247 C CA . SER B 2 153 ? 29.393 41.176 61.035 1.00 37.64 ? 153 SER L CA 1 ATOM 4248 C C . SER B 2 153 ? 30.057 41.036 62.377 1.00 37.76 ? 153 SER L C 1 ATOM 4249 O O . SER B 2 153 ? 30.377 41.999 63.100 1.00 36.80 ? 153 SER L O 1 ATOM 4250 C CB . SER B 2 153 ? 30.406 41.359 59.932 1.00 38.58 ? 153 SER L CB 1 ATOM 4251 O OG . SER B 2 153 ? 29.673 41.730 58.773 1.00 39.52 ? 153 SER L OG 1 ATOM 4252 N N . GLU B 2 154 ? 30.112 39.744 62.679 1.00 37.35 ? 154 GLU L N 1 ATOM 4253 C CA . GLU B 2 154 ? 30.757 39.264 63.887 1.00 36.79 ? 154 GLU L CA 1 ATOM 4254 C C . GLU B 2 154 ? 32.241 39.624 63.805 1.00 38.41 ? 154 GLU L C 1 ATOM 4255 O O . GLU B 2 154 ? 32.845 39.763 62.723 1.00 39.35 ? 154 GLU L O 1 ATOM 4256 C CB . GLU B 2 154 ? 30.631 37.759 64.006 1.00 34.35 ? 154 GLU L CB 1 ATOM 4257 C CG . GLU B 2 154 ? 29.220 37.274 64.282 1.00 31.56 ? 154 GLU L CG 1 ATOM 4258 C CD . GLU B 2 154 ? 29.191 35.773 64.502 1.00 30.28 ? 154 GLU L CD 1 ATOM 4259 O OE1 . GLU B 2 154 ? 29.580 35.325 65.581 1.00 29.55 ? 154 GLU L OE1 1 ATOM 4260 O OE2 . GLU B 2 154 ? 28.788 35.051 63.591 1.00 29.57 ? 154 GLU L OE2 1 ATOM 4261 N N . ARG B 2 155 ? 32.838 39.791 64.969 1.00 39.33 ? 155 ARG L N 1 ATOM 4262 C CA . ARG B 2 155 ? 34.238 40.079 64.964 1.00 40.38 ? 155 ARG L CA 1 ATOM 4263 C C . ARG B 2 155 ? 34.820 39.307 66.108 1.00 39.92 ? 155 ARG L C 1 ATOM 4264 O O . ARG B 2 155 ? 34.764 39.692 67.272 1.00 41.40 ? 155 ARG L O 1 ATOM 4265 C CB . ARG B 2 155 ? 34.432 41.583 65.126 1.00 41.62 ? 155 ARG L CB 1 ATOM 4266 C CG . ARG B 2 155 ? 35.865 41.961 64.900 1.00 42.24 ? 155 ARG L CG 1 ATOM 4267 C CD . ARG B 2 155 ? 36.342 41.444 63.578 1.00 44.36 ? 155 ARG L CD 1 ATOM 4268 N NE . ARG B 2 155 ? 37.603 42.105 63.446 1.00 48.14 ? 155 ARG L NE 1 ATOM 4269 C CZ . ARG B 2 155 ? 37.840 42.891 62.412 1.00 51.38 ? 155 ARG L CZ 1 ATOM 4270 N NH1 . ARG B 2 155 ? 36.981 42.971 61.384 1.00 52.50 ? 155 ARG L NH1 1 ATOM 4271 N NH2 . ARG B 2 155 ? 38.985 43.567 62.429 1.00 52.03 ? 155 ARG L NH2 1 ATOM 4272 N N . GLN B 2 156 ? 35.329 38.132 65.761 1.00 39.78 ? 156 GLN L N 1 ATOM 4273 C CA . GLN B 2 156 ? 35.945 37.257 66.747 1.00 38.57 ? 156 GLN L CA 1 ATOM 4274 C C . GLN B 2 156 ? 37.408 37.404 66.365 1.00 40.73 ? 156 GLN L C 1 ATOM 4275 O O . GLN B 2 156 ? 37.729 36.955 65.268 1.00 43.59 ? 156 GLN L O 1 ATOM 4276 C CB . GLN B 2 156 ? 35.416 35.828 66.546 1.00 35.62 ? 156 GLN L CB 1 ATOM 4277 C CG . GLN B 2 156 ? 33.893 35.737 66.698 1.00 32.19 ? 156 GLN L CG 1 ATOM 4278 C CD . GLN B 2 156 ? 33.323 34.332 66.581 1.00 30.53 ? 156 GLN L CD 1 ATOM 4279 O OE1 . GLN B 2 156 ? 33.393 33.530 67.503 1.00 29.56 ? 156 GLN L OE1 1 ATOM 4280 N NE2 . GLN B 2 156 ? 32.699 33.965 65.475 1.00 29.60 ? 156 GLN L NE2 1 ATOM 4281 N N . ASN B 2 157 ? 38.214 38.128 67.161 1.00 42.88 ? 157 ASN L N 1 ATOM 4282 C CA . ASN B 2 157 ? 39.659 38.413 67.037 1.00 44.28 ? 157 ASN L CA 1 ATOM 4283 C C . ASN B 2 157 ? 40.021 39.901 67.058 1.00 42.61 ? 157 ASN L C 1 ATOM 4284 O O . ASN B 2 157 ? 39.266 40.780 66.639 1.00 44.40 ? 157 ASN L O 1 ATOM 4285 C CB . ASN B 2 157 ? 40.358 37.865 65.756 1.00 47.60 ? 157 ASN L CB 1 ATOM 4286 C CG . ASN B 2 157 ? 40.171 38.551 64.408 1.00 50.73 ? 157 ASN L CG 1 ATOM 4287 O OD1 . ASN B 2 157 ? 40.598 39.681 64.186 1.00 52.99 ? 157 ASN L OD1 1 ATOM 4288 N ND2 . ASN B 2 157 ? 39.554 37.836 63.475 1.00 51.97 ? 157 ASN L ND2 1 ATOM 4289 N N . GLY B 2 158 ? 41.222 40.187 67.563 1.00 40.58 ? 158 GLY L N 1 ATOM 4290 C CA . GLY B 2 158 ? 41.645 41.550 67.864 1.00 37.43 ? 158 GLY L CA 1 ATOM 4291 C C . GLY B 2 158 ? 41.154 41.997 69.255 1.00 36.43 ? 158 GLY L C 1 ATOM 4292 O O . GLY B 2 158 ? 41.498 43.080 69.757 1.00 37.22 ? 158 GLY L O 1 ATOM 4293 N N . VAL B 2 159 ? 40.333 41.136 69.885 1.00 35.29 ? 159 VAL L N 1 ATOM 4294 C CA . VAL B 2 159 ? 39.732 41.341 71.203 1.00 33.02 ? 159 VAL L CA 1 ATOM 4295 C C . VAL B 2 159 ? 40.586 40.750 72.319 1.00 32.33 ? 159 VAL L C 1 ATOM 4296 O O . VAL B 2 159 ? 41.154 39.648 72.175 1.00 32.51 ? 159 VAL L O 1 ATOM 4297 C CB . VAL B 2 159 ? 38.334 40.691 71.315 1.00 30.84 ? 159 VAL L CB 1 ATOM 4298 C CG1 . VAL B 2 159 ? 37.618 41.198 72.549 1.00 30.51 ? 159 VAL L CG1 1 ATOM 4299 C CG2 . VAL B 2 159 ? 37.508 41.039 70.112 1.00 29.80 ? 159 VAL L CG2 1 ATOM 4300 N N . LEU B 2 160 ? 40.626 41.554 73.395 1.00 30.55 ? 160 LEU L N 1 ATOM 4301 C CA . LEU B 2 160 ? 41.281 41.181 74.631 1.00 30.21 ? 160 LEU L CA 1 ATOM 4302 C C . LEU B 2 160 ? 40.219 41.383 75.720 1.00 31.08 ? 160 LEU L C 1 ATOM 4303 O O . LEU B 2 160 ? 39.582 42.454 75.796 1.00 30.83 ? 160 LEU L O 1 ATOM 4304 C CB . LEU B 2 160 ? 42.436 42.082 74.972 1.00 28.60 ? 160 LEU L CB 1 ATOM 4305 C CG . LEU B 2 160 ? 43.533 42.459 73.987 1.00 28.19 ? 160 LEU L CG 1 ATOM 4306 C CD1 . LEU B 2 160 ? 43.086 43.356 72.763 1.00 29.11 ? 160 LEU L CD1 1 ATOM 4307 C CD2 . LEU B 2 160 ? 44.532 43.223 74.872 1.00 28.95 ? 160 LEU L CD2 1 ATOM 4308 N N . ASN B 2 161 ? 40.010 40.384 76.587 1.00 31.22 ? 161 ASN L N 1 ATOM 4309 C CA . ASN B 2 161 ? 39.063 40.509 77.685 1.00 31.54 ? 161 ASN L CA 1 ATOM 4310 C C . ASN B 2 161 ? 39.790 40.397 79.015 1.00 33.29 ? 161 ASN L C 1 ATOM 4311 O O . ASN B 2 161 ? 40.858 39.769 79.072 1.00 33.19 ? 161 ASN L O 1 ATOM 4312 C CB . ASN B 2 161 ? 38.011 39.413 77.652 1.00 31.65 ? 161 ASN L CB 1 ATOM 4313 C CG . ASN B 2 161 ? 37.158 39.391 76.409 1.00 31.09 ? 161 ASN L CG 1 ATOM 4314 O OD1 . ASN B 2 161 ? 37.483 39.970 75.385 1.00 31.34 ? 161 ASN L OD1 1 ATOM 4315 N ND2 . ASN B 2 161 ? 36.009 38.751 76.410 1.00 30.22 ? 161 ASN L ND2 1 ATOM 4316 N N . SER B 2 162 ? 39.236 41.023 80.067 1.00 34.17 ? 162 SER L N 1 ATOM 4317 C CA . SER B 2 162 ? 39.741 40.884 81.433 1.00 32.83 ? 162 SER L CA 1 ATOM 4318 C C . SER B 2 162 ? 38.579 41.081 82.392 1.00 34.87 ? 162 SER L C 1 ATOM 4319 O O . SER B 2 162 ? 37.750 41.982 82.242 1.00 35.32 ? 162 SER L O 1 ATOM 4320 C CB . SER B 2 162 ? 40.796 41.902 81.780 1.00 30.49 ? 162 SER L CB 1 ATOM 4321 O OG . SER B 2 162 ? 41.393 41.469 82.992 1.00 29.32 ? 162 SER L OG 1 ATOM 4322 N N . TRP B 2 163 ? 38.506 40.175 83.351 1.00 37.61 ? 163 TRP L N 1 ATOM 4323 C CA . TRP B 2 163 ? 37.446 40.161 84.322 1.00 38.95 ? 163 TRP L CA 1 ATOM 4324 C C . TRP B 2 163 ? 38.156 40.537 85.602 1.00 36.47 ? 163 TRP L C 1 ATOM 4325 O O . TRP B 2 163 ? 39.318 40.216 85.863 1.00 36.20 ? 163 TRP L O 1 ATOM 4326 C CB . TRP B 2 163 ? 36.828 38.780 84.533 1.00 43.65 ? 163 TRP L CB 1 ATOM 4327 C CG . TRP B 2 163 ? 36.323 38.014 83.299 1.00 48.39 ? 163 TRP L CG 1 ATOM 4328 C CD1 . TRP B 2 163 ? 34.997 37.635 83.208 1.00 50.32 ? 163 TRP L CD1 1 ATOM 4329 C CD2 . TRP B 2 163 ? 37.070 37.578 82.211 1.00 51.26 ? 163 TRP L CD2 1 ATOM 4330 N NE1 . TRP B 2 163 ? 34.908 36.968 82.075 1.00 51.65 ? 163 TRP L NE1 1 ATOM 4331 C CE2 . TRP B 2 163 ? 36.107 36.914 81.456 1.00 52.18 ? 163 TRP L CE2 1 ATOM 4332 C CE3 . TRP B 2 163 ? 38.374 37.629 81.747 1.00 51.93 ? 163 TRP L CE3 1 ATOM 4333 C CZ2 . TRP B 2 163 ? 36.438 36.306 80.252 1.00 52.55 ? 163 TRP L CZ2 1 ATOM 4334 C CZ3 . TRP B 2 163 ? 38.713 37.025 80.552 1.00 52.76 ? 163 TRP L CZ3 1 ATOM 4335 C CH2 . TRP B 2 163 ? 37.752 36.367 79.812 1.00 53.51 ? 163 TRP L CH2 1 ATOM 4336 N N . THR B 2 164 ? 37.441 41.362 86.317 1.00 33.37 ? 164 THR L N 1 ATOM 4337 C CA . THR B 2 164 ? 37.760 41.707 87.668 1.00 31.62 ? 164 THR L CA 1 ATOM 4338 C C . THR B 2 164 ? 37.387 40.422 88.429 1.00 30.69 ? 164 THR L C 1 ATOM 4339 O O . THR B 2 164 ? 36.424 39.740 88.043 1.00 31.12 ? 164 THR L O 1 ATOM 4340 C CB . THR B 2 164 ? 36.879 42.947 87.889 1.00 30.18 ? 164 THR L CB 1 ATOM 4341 O OG1 . THR B 2 164 ? 37.823 44.007 87.872 1.00 30.61 ? 164 THR L OG1 1 ATOM 4342 C CG2 . THR B 2 164 ? 35.949 42.909 89.100 1.00 30.31 ? 164 THR L CG2 1 ATOM 4343 N N . ASP B 2 165 ? 38.146 40.008 89.453 1.00 30.85 ? 165 ASP L N 1 ATOM 4344 C CA . ASP B 2 165 ? 37.754 38.895 90.306 1.00 32.58 ? 165 ASP L CA 1 ATOM 4345 C C . ASP B 2 165 ? 36.522 39.378 91.094 1.00 32.75 ? 165 ASP L C 1 ATOM 4346 O O . ASP B 2 165 ? 36.329 40.596 91.208 1.00 34.51 ? 165 ASP L O 1 ATOM 4347 C CB . ASP B 2 165 ? 38.899 38.576 91.253 1.00 34.20 ? 165 ASP L CB 1 ATOM 4348 C CG . ASP B 2 165 ? 38.759 37.296 92.075 1.00 36.48 ? 165 ASP L CG 1 ATOM 4349 O OD1 . ASP B 2 165 ? 37.650 36.873 92.420 1.00 35.94 ? 165 ASP L OD1 1 ATOM 4350 O OD2 . ASP B 2 165 ? 39.809 36.718 92.379 1.00 38.90 ? 165 ASP L OD2 1 ATOM 4351 N N . GLN B 2 166 ? 35.659 38.495 91.620 1.00 30.06 ? 166 GLN L N 1 ATOM 4352 C CA . GLN B 2 166 ? 34.511 38.889 92.404 1.00 28.29 ? 166 GLN L CA 1 ATOM 4353 C C . GLN B 2 166 ? 34.773 39.948 93.464 1.00 28.19 ? 166 GLN L C 1 ATOM 4354 O O . GLN B 2 166 ? 35.719 39.860 94.228 1.00 28.59 ? 166 GLN L O 1 ATOM 4355 C CB . GLN B 2 166 ? 33.917 37.659 93.063 1.00 27.23 ? 166 GLN L CB 1 ATOM 4356 C CG . GLN B 2 166 ? 32.577 37.990 93.706 1.00 26.43 ? 166 GLN L CG 1 ATOM 4357 C CD . GLN B 2 166 ? 31.738 36.794 93.995 1.00 26.47 ? 166 GLN L CD 1 ATOM 4358 O OE1 . GLN B 2 166 ? 32.237 35.697 94.196 1.00 28.44 ? 166 GLN L OE1 1 ATOM 4359 N NE2 . GLN B 2 166 ? 30.433 36.927 93.922 1.00 26.71 ? 166 GLN L NE2 1 ATOM 4360 N N . ASP B 2 167 ? 33.870 40.927 93.524 1.00 28.24 ? 167 ASP L N 1 ATOM 4361 C CA . ASP B 2 167 ? 33.933 42.081 94.392 1.00 27.35 ? 167 ASP L CA 1 ATOM 4362 C C . ASP B 2 167 ? 33.638 41.657 95.815 1.00 26.48 ? 167 ASP L C 1 ATOM 4363 O O . ASP B 2 167 ? 32.593 41.111 96.130 1.00 25.60 ? 167 ASP L O 1 ATOM 4364 C CB . ASP B 2 167 ? 32.905 43.129 93.902 1.00 28.54 ? 167 ASP L CB 1 ATOM 4365 C CG . ASP B 2 167 ? 32.983 44.551 94.495 1.00 32.23 ? 167 ASP L CG 1 ATOM 4366 O OD1 . ASP B 2 167 ? 32.743 44.708 95.693 1.00 32.84 ? 167 ASP L OD1 1 ATOM 4367 O OD2 . ASP B 2 167 ? 33.240 45.515 93.763 1.00 34.26 ? 167 ASP L OD2 1 ATOM 4368 N N . SER B 2 168 ? 34.540 41.978 96.702 1.00 26.50 ? 168 SER L N 1 ATOM 4369 C CA . SER B 2 168 ? 34.414 41.625 98.091 1.00 26.79 ? 168 SER L CA 1 ATOM 4370 C C . SER B 2 168 ? 33.295 42.339 98.771 1.00 26.75 ? 168 SER L C 1 ATOM 4371 O O . SER B 2 168 ? 32.861 41.860 99.802 1.00 28.26 ? 168 SER L O 1 ATOM 4372 C CB . SER B 2 168 ? 35.699 41.952 98.855 1.00 27.88 ? 168 SER L CB 1 ATOM 4373 O OG . SER B 2 168 ? 36.076 43.327 98.709 1.00 31.03 ? 168 SER L OG 1 ATOM 4374 N N . LYS B 2 169 ? 32.925 43.520 98.273 1.00 26.14 ? 169 LYS L N 1 ATOM 4375 C CA . LYS B 2 169 ? 31.910 44.312 98.928 1.00 25.02 ? 169 LYS L CA 1 ATOM 4376 C C . LYS B 2 169 ? 30.531 43.926 98.497 1.00 23.47 ? 169 LYS L C 1 ATOM 4377 O O . LYS B 2 169 ? 29.725 43.488 99.303 1.00 23.64 ? 169 LYS L O 1 ATOM 4378 C CB . LYS B 2 169 ? 32.135 45.762 98.638 1.00 26.28 ? 169 LYS L CB 1 ATOM 4379 C CG . LYS B 2 169 ? 33.417 46.169 99.367 1.00 29.64 ? 169 LYS L CG 1 ATOM 4380 C CD . LYS B 2 169 ? 33.843 47.652 99.248 1.00 32.62 ? 169 LYS L CD 1 ATOM 4381 C CE . LYS B 2 169 ? 34.298 48.087 97.822 1.00 34.65 ? 169 LYS L CE 1 ATOM 4382 N NZ . LYS B 2 169 ? 33.210 48.318 96.861 1.00 40.73 ? 169 LYS L NZ 1 ATOM 4383 N N . ASP B 2 170 ? 30.241 44.078 97.216 1.00 23.60 ? 170 ASP L N 1 ATOM 4384 C CA . ASP B 2 170 ? 28.942 43.711 96.717 1.00 22.92 ? 170 ASP L CA 1 ATOM 4385 C C . ASP B 2 170 ? 29.008 42.533 95.766 1.00 21.82 ? 170 ASP L C 1 ATOM 4386 O O . ASP B 2 170 ? 28.606 42.643 94.616 1.00 22.27 ? 170 ASP L O 1 ATOM 4387 C CB . ASP B 2 170 ? 28.348 44.965 96.064 1.00 24.43 ? 170 ASP L CB 1 ATOM 4388 C CG . ASP B 2 170 ? 28.898 45.477 94.719 1.00 24.56 ? 170 ASP L CG 1 ATOM 4389 O OD1 . ASP B 2 170 ? 29.957 45.018 94.263 1.00 23.03 ? 170 ASP L OD1 1 ATOM 4390 O OD2 . ASP B 2 170 ? 28.210 46.329 94.124 1.00 25.86 ? 170 ASP L OD2 1 ATOM 4391 N N . SER B 2 171 ? 29.594 41.436 96.194 1.00 22.08 ? 171 SER L N 1 ATOM 4392 C CA . SER B 2 171 ? 29.728 40.189 95.454 1.00 20.98 ? 171 SER L CA 1 ATOM 4393 C C . SER B 2 171 ? 29.421 40.086 93.945 1.00 21.02 ? 171 SER L C 1 ATOM 4394 O O . SER B 2 171 ? 28.653 39.202 93.532 1.00 22.25 ? 171 SER L O 1 ATOM 4395 C CB . SER B 2 171 ? 28.910 39.224 96.298 1.00 19.21 ? 171 SER L CB 1 ATOM 4396 O OG . SER B 2 171 ? 29.310 39.321 97.671 1.00 19.02 ? 171 SER L OG 1 ATOM 4397 N N . THR B 2 172 ? 30.044 40.905 93.082 1.00 19.33 ? 172 THR L N 1 ATOM 4398 C CA . THR B 2 172 ? 29.660 40.943 91.677 1.00 18.24 ? 172 THR L CA 1 ATOM 4399 C C . THR B 2 172 ? 30.886 40.770 90.819 1.00 19.16 ? 172 THR L C 1 ATOM 4400 O O . THR B 2 172 ? 31.982 40.793 91.386 1.00 20.85 ? 172 THR L O 1 ATOM 4401 C CB . THR B 2 172 ? 29.004 42.281 91.324 1.00 17.30 ? 172 THR L CB 1 ATOM 4402 O OG1 . THR B 2 172 ? 29.728 43.309 91.983 1.00 16.57 ? 172 THR L OG1 1 ATOM 4403 C CG2 . THR B 2 172 ? 27.534 42.257 91.687 1.00 16.98 ? 172 THR L CG2 1 ATOM 4404 N N . TYR B 2 173 ? 30.796 40.553 89.505 1.00 18.43 ? 173 TYR L N 1 ATOM 4405 C CA . TYR B 2 173 ? 31.986 40.521 88.669 1.00 18.50 ? 173 TYR L CA 1 ATOM 4406 C C . TYR B 2 173 ? 31.898 41.693 87.673 1.00 19.56 ? 173 TYR L C 1 ATOM 4407 O O . TYR B 2 173 ? 30.829 42.305 87.585 1.00 18.81 ? 173 TYR L O 1 ATOM 4408 C CB . TYR B 2 173 ? 32.044 39.224 87.927 1.00 17.93 ? 173 TYR L CB 1 ATOM 4409 C CG . TYR B 2 173 ? 32.150 38.030 88.853 1.00 19.20 ? 173 TYR L CG 1 ATOM 4410 C CD1 . TYR B 2 173 ? 31.039 37.598 89.568 1.00 18.45 ? 173 TYR L CD1 1 ATOM 4411 C CD2 . TYR B 2 173 ? 33.366 37.381 88.972 1.00 19.17 ? 173 TYR L CD2 1 ATOM 4412 C CE1 . TYR B 2 173 ? 31.153 36.502 90.406 1.00 18.99 ? 173 TYR L CE1 1 ATOM 4413 C CE2 . TYR B 2 173 ? 33.479 36.289 89.802 1.00 19.55 ? 173 TYR L CE2 1 ATOM 4414 C CZ . TYR B 2 173 ? 32.375 35.865 90.516 1.00 19.24 ? 173 TYR L CZ 1 ATOM 4415 O OH . TYR B 2 173 ? 32.505 34.786 91.361 1.00 21.23 ? 173 TYR L OH 1 ATOM 4416 N N . SER B 2 174 ? 32.957 42.078 86.943 1.00 20.23 ? 174 SER L N 1 ATOM 4417 C CA . SER B 2 174 ? 32.936 43.145 85.956 1.00 21.38 ? 174 SER L CA 1 ATOM 4418 C C . SER B 2 174 ? 33.984 42.879 84.878 1.00 22.55 ? 174 SER L C 1 ATOM 4419 O O . SER B 2 174 ? 34.999 42.267 85.196 1.00 25.55 ? 174 SER L O 1 ATOM 4420 C CB . SER B 2 174 ? 33.224 44.443 86.634 1.00 23.76 ? 174 SER L CB 1 ATOM 4421 O OG . SER B 2 174 ? 32.215 44.713 87.605 1.00 26.34 ? 174 SER L OG 1 ATOM 4422 N N . MET B 2 175 ? 33.874 43.304 83.628 1.00 21.78 ? 175 MET L N 1 ATOM 4423 C CA . MET B 2 175 ? 34.791 42.860 82.601 1.00 20.12 ? 175 MET L CA 1 ATOM 4424 C C . MET B 2 175 ? 35.095 43.910 81.523 1.00 21.66 ? 175 MET L C 1 ATOM 4425 O O . MET B 2 175 ? 34.185 44.686 81.207 1.00 23.09 ? 175 MET L O 1 ATOM 4426 C CB . MET B 2 175 ? 34.148 41.621 82.052 1.00 18.37 ? 175 MET L CB 1 ATOM 4427 C CG . MET B 2 175 ? 34.858 41.098 80.854 1.00 19.91 ? 175 MET L CG 1 ATOM 4428 S SD . MET B 2 175 ? 33.607 40.703 79.641 1.00 20.84 ? 175 MET L SD 1 ATOM 4429 C CE . MET B 2 175 ? 33.774 38.956 79.545 1.00 20.37 ? 175 MET L CE 1 ATOM 4430 N N . SER B 2 176 ? 36.334 44.077 81.030 1.00 20.07 ? 176 SER L N 1 ATOM 4431 C CA . SER B 2 176 ? 36.643 44.956 79.903 1.00 19.80 ? 176 SER L CA 1 ATOM 4432 C C . SER B 2 176 ? 36.726 43.976 78.765 1.00 21.12 ? 176 SER L C 1 ATOM 4433 O O . SER B 2 176 ? 37.137 42.811 78.908 1.00 22.71 ? 176 SER L O 1 ATOM 4434 C CB . SER B 2 176 ? 38.036 45.686 79.928 1.00 19.82 ? 176 SER L CB 1 ATOM 4435 O OG . SER B 2 176 ? 38.112 47.003 80.492 1.00 21.04 ? 176 SER L OG 1 ATOM 4436 N N . SER B 2 177 ? 36.311 44.499 77.633 1.00 21.17 ? 177 SER L N 1 ATOM 4437 C CA . SER B 2 177 ? 36.343 43.778 76.391 1.00 20.51 ? 177 SER L CA 1 ATOM 4438 C C . SER B 2 177 ? 36.883 44.813 75.430 1.00 19.22 ? 177 SER L C 1 ATOM 4439 O O . SER B 2 177 ? 36.249 45.842 75.169 1.00 19.65 ? 177 SER L O 1 ATOM 4440 C CB . SER B 2 177 ? 34.955 43.364 76.008 1.00 17.15 ? 177 SER L CB 1 ATOM 4441 O OG . SER B 2 177 ? 35.174 42.408 75.001 1.00 15.43 ? 177 SER L OG 1 ATOM 4442 N N . THR B 2 178 ? 38.060 44.582 74.909 1.00 20.49 ? 178 THR L N 1 ATOM 4443 C CA . THR B 2 178 ? 38.691 45.581 74.083 1.00 23.15 ? 178 THR L CA 1 ATOM 4444 C C . THR B 2 178 ? 38.889 45.112 72.637 1.00 24.90 ? 178 THR L C 1 ATOM 4445 O O . THR B 2 178 ? 39.411 44.008 72.433 1.00 26.05 ? 178 THR L O 1 ATOM 4446 C CB . THR B 2 178 ? 40.003 45.935 74.770 1.00 24.71 ? 178 THR L CB 1 ATOM 4447 O OG1 . THR B 2 178 ? 39.809 45.960 76.191 1.00 25.44 ? 178 THR L OG1 1 ATOM 4448 C CG2 . THR B 2 178 ? 40.498 47.263 74.261 1.00 26.50 ? 178 THR L CG2 1 ATOM 4449 N N . LEU B 2 179 ? 38.475 45.908 71.630 1.00 26.78 ? 179 LEU L N 1 ATOM 4450 C CA . LEU B 2 179 ? 38.591 45.621 70.201 1.00 26.89 ? 179 LEU L CA 1 ATOM 4451 C C . LEU B 2 179 ? 39.711 46.519 69.713 1.00 27.53 ? 179 LEU L C 1 ATOM 4452 O O . LEU B 2 179 ? 39.664 47.715 70.017 1.00 28.79 ? 179 LEU L O 1 ATOM 4453 C CB . LEU B 2 179 ? 37.339 46.004 69.470 1.00 26.06 ? 179 LEU L CB 1 ATOM 4454 C CG . LEU B 2 179 ? 37.308 45.406 68.084 1.00 25.98 ? 179 LEU L CG 1 ATOM 4455 C CD1 . LEU B 2 179 ? 37.044 43.914 68.210 1.00 25.31 ? 179 LEU L CD1 1 ATOM 4456 C CD2 . LEU B 2 179 ? 36.187 45.998 67.251 1.00 26.86 ? 179 LEU L CD2 1 ATOM 4457 N N . THR B 2 180 ? 40.753 46.061 69.023 1.00 29.75 ? 180 THR L N 1 ATOM 4458 C CA . THR B 2 180 ? 41.777 46.999 68.595 1.00 33.07 ? 180 THR L CA 1 ATOM 4459 C C . THR B 2 180 ? 42.092 46.918 67.093 1.00 33.49 ? 180 THR L C 1 ATOM 4460 O O . THR B 2 180 ? 42.758 46.013 66.577 1.00 34.51 ? 180 THR L O 1 ATOM 4461 C CB . THR B 2 180 ? 42.980 46.713 69.496 1.00 32.82 ? 180 THR L CB 1 ATOM 4462 O OG1 . THR B 2 180 ? 42.510 46.821 70.840 1.00 33.90 ? 180 THR L OG1 1 ATOM 4463 C CG2 . THR B 2 180 ? 44.129 47.693 69.246 1.00 32.83 ? 180 THR L CG2 1 ATOM 4464 N N . LEU B 2 181 ? 41.493 47.848 66.348 1.00 33.52 ? 181 LEU L N 1 ATOM 4465 C CA . LEU B 2 181 ? 41.652 47.887 64.911 1.00 32.25 ? 181 LEU L CA 1 ATOM 4466 C C . LEU B 2 181 ? 42.756 48.867 64.535 1.00 33.28 ? 181 LEU L C 1 ATOM 4467 O O . LEU B 2 181 ? 43.446 49.514 65.342 1.00 34.56 ? 181 LEU L O 1 ATOM 4468 C CB . LEU B 2 181 ? 40.329 48.313 64.210 1.00 29.36 ? 181 LEU L CB 1 ATOM 4469 C CG . LEU B 2 181 ? 38.974 47.838 64.724 1.00 27.22 ? 181 LEU L CG 1 ATOM 4470 C CD1 . LEU B 2 181 ? 38.401 48.923 65.636 1.00 28.77 ? 181 LEU L CD1 1 ATOM 4471 C CD2 . LEU B 2 181 ? 37.988 47.645 63.589 1.00 25.71 ? 181 LEU L CD2 1 ATOM 4472 N N . THR B 2 182 ? 42.954 48.902 63.228 1.00 34.51 ? 182 THR L N 1 ATOM 4473 C CA . THR B 2 182 ? 43.842 49.854 62.594 1.00 35.28 ? 182 THR L CA 1 ATOM 4474 C C . THR B 2 182 ? 42.983 51.104 62.413 1.00 34.08 ? 182 THR L C 1 ATOM 4475 O O . THR B 2 182 ? 41.759 50.991 62.201 1.00 32.30 ? 182 THR L O 1 ATOM 4476 C CB . THR B 2 182 ? 44.296 49.306 61.237 1.00 35.21 ? 182 THR L CB 1 ATOM 4477 O OG1 . THR B 2 182 ? 43.383 48.258 60.877 1.00 37.78 ? 182 THR L OG1 1 ATOM 4478 C CG2 . THR B 2 182 ? 45.730 48.834 61.281 1.00 35.84 ? 182 THR L CG2 1 ATOM 4479 N N . LYS B 2 183 ? 43.619 52.291 62.473 1.00 33.32 ? 183 LYS L N 1 ATOM 4480 C CA . LYS B 2 183 ? 42.936 53.538 62.208 1.00 33.91 ? 183 LYS L CA 1 ATOM 4481 C C . LYS B 2 183 ? 42.159 53.330 60.912 1.00 34.78 ? 183 LYS L C 1 ATOM 4482 O O . LYS B 2 183 ? 40.952 53.449 60.953 1.00 35.28 ? 183 LYS L O 1 ATOM 4483 C CB . LYS B 2 183 ? 43.941 54.646 62.049 1.00 33.38 ? 183 LYS L CB 1 ATOM 4484 C CG . LYS B 2 183 ? 43.239 55.982 61.940 1.00 33.77 ? 183 LYS L CG 1 ATOM 4485 C CD . LYS B 2 183 ? 44.238 57.133 61.739 1.00 34.80 ? 183 LYS L CD 1 ATOM 4486 C CE . LYS B 2 183 ? 43.468 58.331 61.181 1.00 35.13 ? 183 LYS L CE 1 ATOM 4487 N NZ . LYS B 2 183 ? 42.323 58.721 62.006 1.00 37.11 ? 183 LYS L NZ 1 ATOM 4488 N N . ASP B 2 184 ? 42.762 52.846 59.820 1.00 37.11 ? 184 ASP L N 1 ATOM 4489 C CA . ASP B 2 184 ? 42.064 52.560 58.562 1.00 37.97 ? 184 ASP L CA 1 ATOM 4490 C C . ASP B 2 184 ? 40.893 51.628 58.706 1.00 37.21 ? 184 ASP L C 1 ATOM 4491 O O . ASP B 2 184 ? 39.871 51.909 58.110 1.00 39.16 ? 184 ASP L O 1 ATOM 4492 C CB . ASP B 2 184 ? 42.979 51.911 57.506 1.00 40.56 ? 184 ASP L CB 1 ATOM 4493 C CG . ASP B 2 184 ? 44.307 52.625 57.391 1.00 44.95 ? 184 ASP L CG 1 ATOM 4494 O OD1 . ASP B 2 184 ? 44.353 53.726 56.830 1.00 46.15 ? 184 ASP L OD1 1 ATOM 4495 O OD2 . ASP B 2 184 ? 45.284 52.084 57.915 1.00 47.14 ? 184 ASP L OD2 1 ATOM 4496 N N . GLU B 2 185 ? 40.962 50.552 59.474 1.00 35.64 ? 185 GLU L N 1 ATOM 4497 C CA . GLU B 2 185 ? 39.844 49.649 59.509 1.00 33.46 ? 185 GLU L CA 1 ATOM 4498 C C . GLU B 2 185 ? 38.725 50.294 60.283 1.00 32.95 ? 185 GLU L C 1 ATOM 4499 O O . GLU B 2 185 ? 37.537 50.168 59.936 1.00 31.53 ? 185 GLU L O 1 ATOM 4500 C CB . GLU B 2 185 ? 40.252 48.340 60.159 1.00 34.02 ? 185 GLU L CB 1 ATOM 4501 C CG . GLU B 2 185 ? 39.121 47.294 60.097 1.00 34.14 ? 185 GLU L CG 1 ATOM 4502 C CD . GLU B 2 185 ? 39.569 45.855 60.311 1.00 34.87 ? 185 GLU L CD 1 ATOM 4503 O OE1 . GLU B 2 185 ? 40.422 45.599 61.175 1.00 36.26 ? 185 GLU L OE1 1 ATOM 4504 O OE2 . GLU B 2 185 ? 39.052 44.985 59.599 1.00 33.93 ? 185 GLU L OE2 1 ATOM 4505 N N . TYR B 2 186 ? 39.161 51.027 61.305 1.00 33.13 ? 186 TYR L N 1 ATOM 4506 C CA . TYR B 2 186 ? 38.217 51.766 62.100 1.00 33.93 ? 186 TYR L CA 1 ATOM 4507 C C . TYR B 2 186 ? 37.560 52.816 61.188 1.00 31.59 ? 186 TYR L C 1 ATOM 4508 O O . TYR B 2 186 ? 36.361 52.711 60.950 1.00 30.65 ? 186 TYR L O 1 ATOM 4509 C CB . TYR B 2 186 ? 38.938 52.416 63.279 1.00 34.77 ? 186 TYR L CB 1 ATOM 4510 C CG . TYR B 2 186 ? 37.923 53.225 64.070 1.00 35.95 ? 186 TYR L CG 1 ATOM 4511 C CD1 . TYR B 2 186 ? 36.910 52.534 64.725 1.00 35.14 ? 186 TYR L CD1 1 ATOM 4512 C CD2 . TYR B 2 186 ? 37.963 54.622 64.072 1.00 36.26 ? 186 TYR L CD2 1 ATOM 4513 C CE1 . TYR B 2 186 ? 35.914 53.219 65.384 1.00 35.13 ? 186 TYR L CE1 1 ATOM 4514 C CE2 . TYR B 2 186 ? 36.963 55.317 64.740 1.00 36.62 ? 186 TYR L CE2 1 ATOM 4515 C CZ . TYR B 2 186 ? 35.950 54.600 65.387 1.00 36.39 ? 186 TYR L CZ 1 ATOM 4516 O OH . TYR B 2 186 ? 34.956 55.256 66.086 1.00 36.35 ? 186 TYR L OH 1 ATOM 4517 N N . GLU B 2 187 ? 38.329 53.780 60.651 1.00 32.18 ? 187 GLU L N 1 ATOM 4518 C CA . GLU B 2 187 ? 37.927 54.801 59.690 1.00 32.83 ? 187 GLU L CA 1 ATOM 4519 C C . GLU B 2 187 ? 37.383 54.219 58.384 1.00 32.25 ? 187 GLU L C 1 ATOM 4520 O O . GLU B 2 187 ? 37.134 54.990 57.455 1.00 32.56 ? 187 GLU L O 1 ATOM 4521 C CB . GLU B 2 187 ? 39.115 55.747 59.341 1.00 32.53 ? 187 GLU L CB 1 ATOM 4522 C CG . GLU B 2 187 ? 39.804 56.551 60.474 1.00 34.39 ? 187 GLU L CG 1 ATOM 4523 C CD . GLU B 2 187 ? 39.599 58.087 60.632 1.00 37.02 ? 187 GLU L CD 1 ATOM 4524 O OE1 . GLU B 2 187 ? 40.196 58.840 59.845 1.00 38.88 ? 187 GLU L OE1 1 ATOM 4525 O OE2 . GLU B 2 187 ? 38.914 58.541 61.573 1.00 36.78 ? 187 GLU L OE2 1 ATOM 4526 N N . ARG B 2 188 ? 37.247 52.895 58.211 1.00 31.43 ? 188 ARG L N 1 ATOM 4527 C CA . ARG B 2 188 ? 36.564 52.327 57.063 1.00 30.63 ? 188 ARG L CA 1 ATOM 4528 C C . ARG B 2 188 ? 35.168 51.903 57.495 1.00 31.82 ? 188 ARG L C 1 ATOM 4529 O O . ARG B 2 188 ? 34.327 51.511 56.678 1.00 33.55 ? 188 ARG L O 1 ATOM 4530 C CB . ARG B 2 188 ? 37.214 51.068 56.521 1.00 28.67 ? 188 ARG L CB 1 ATOM 4531 C CG . ARG B 2 188 ? 38.270 51.208 55.447 1.00 26.90 ? 188 ARG L CG 1 ATOM 4532 C CD . ARG B 2 188 ? 38.240 49.959 54.573 1.00 25.56 ? 188 ARG L CD 1 ATOM 4533 N NE . ARG B 2 188 ? 38.255 48.700 55.311 1.00 24.41 ? 188 ARG L NE 1 ATOM 4534 C CZ . ARG B 2 188 ? 39.367 48.173 55.837 1.00 23.87 ? 188 ARG L CZ 1 ATOM 4535 N NH1 . ARG B 2 188 ? 40.529 48.825 55.866 1.00 23.37 ? 188 ARG L NH1 1 ATOM 4536 N NH2 . ARG B 2 188 ? 39.294 46.998 56.450 1.00 23.73 ? 188 ARG L NH2 1 ATOM 4537 N N . HIS B 2 189 ? 34.869 51.886 58.786 1.00 32.90 ? 189 HIS L N 1 ATOM 4538 C CA . HIS B 2 189 ? 33.560 51.487 59.231 1.00 35.15 ? 189 HIS L CA 1 ATOM 4539 C C . HIS B 2 189 ? 32.665 52.453 59.946 1.00 34.73 ? 189 HIS L C 1 ATOM 4540 O O . HIS B 2 189 ? 32.927 53.652 60.091 1.00 34.92 ? 189 HIS L O 1 ATOM 4541 C CB . HIS B 2 189 ? 33.754 50.285 60.069 1.00 36.96 ? 189 HIS L CB 1 ATOM 4542 C CG . HIS B 2 189 ? 33.644 49.089 59.173 1.00 38.17 ? 189 HIS L CG 1 ATOM 4543 N ND1 . HIS B 2 189 ? 32.626 48.802 58.380 1.00 39.33 ? 189 HIS L ND1 1 ATOM 4544 C CD2 . HIS B 2 189 ? 34.567 48.079 59.099 1.00 39.27 ? 189 HIS L CD2 1 ATOM 4545 C CE1 . HIS B 2 189 ? 32.880 47.644 57.829 1.00 41.53 ? 189 HIS L CE1 1 ATOM 4546 N NE2 . HIS B 2 189 ? 34.046 47.218 58.268 1.00 40.74 ? 189 HIS L NE2 1 ATOM 4547 N N . ASN B 2 190 ? 31.511 51.901 60.322 1.00 36.39 ? 190 ASN L N 1 ATOM 4548 C CA . ASN B 2 190 ? 30.581 52.713 61.068 1.00 40.81 ? 190 ASN L CA 1 ATOM 4549 C C . ASN B 2 190 ? 29.814 52.054 62.170 1.00 40.14 ? 190 ASN L C 1 ATOM 4550 O O . ASN B 2 190 ? 29.855 52.658 63.231 1.00 40.89 ? 190 ASN L O 1 ATOM 4551 C CB . ASN B 2 190 ? 29.567 53.388 60.145 1.00 45.49 ? 190 ASN L CB 1 ATOM 4552 C CG . ASN B 2 190 ? 29.253 52.620 58.874 1.00 48.42 ? 190 ASN L CG 1 ATOM 4553 O OD1 . ASN B 2 190 ? 28.742 51.501 58.916 1.00 52.54 ? 190 ASN L OD1 1 ATOM 4554 N ND2 . ASN B 2 190 ? 29.623 53.222 57.747 1.00 48.93 ? 190 ASN L ND2 1 ATOM 4555 N N . SER B 2 191 ? 29.125 50.931 62.112 1.00 38.92 ? 191 SER L N 1 ATOM 4556 C CA . SER B 2 191 ? 28.467 50.459 63.324 1.00 38.57 ? 191 SER L CA 1 ATOM 4557 C C . SER B 2 191 ? 29.297 49.501 64.188 1.00 38.92 ? 191 SER L C 1 ATOM 4558 O O . SER B 2 191 ? 29.632 48.388 63.768 1.00 39.78 ? 191 SER L O 1 ATOM 4559 C CB . SER B 2 191 ? 27.137 49.818 62.920 1.00 39.91 ? 191 SER L CB 1 ATOM 4560 O OG . SER B 2 191 ? 27.108 49.398 61.553 1.00 42.46 ? 191 SER L OG 1 ATOM 4561 N N . TYR B 2 192 ? 29.727 49.941 65.376 1.00 37.04 ? 192 TYR L N 1 ATOM 4562 C CA . TYR B 2 192 ? 30.472 49.113 66.305 1.00 34.95 ? 192 TYR L CA 1 ATOM 4563 C C . TYR B 2 192 ? 29.481 48.761 67.371 1.00 35.11 ? 192 TYR L C 1 ATOM 4564 O O . TYR B 2 192 ? 28.614 49.582 67.725 1.00 34.05 ? 192 TYR L O 1 ATOM 4565 C CB . TYR B 2 192 ? 31.626 49.898 66.871 1.00 32.56 ? 192 TYR L CB 1 ATOM 4566 C CG . TYR B 2 192 ? 32.680 50.123 65.785 1.00 30.61 ? 192 TYR L CG 1 ATOM 4567 C CD1 . TYR B 2 192 ? 32.538 51.177 64.920 1.00 29.79 ? 192 TYR L CD1 1 ATOM 4568 C CD2 . TYR B 2 192 ? 33.735 49.227 65.639 1.00 30.06 ? 192 TYR L CD2 1 ATOM 4569 C CE1 . TYR B 2 192 ? 33.442 51.320 63.902 1.00 29.61 ? 192 TYR L CE1 1 ATOM 4570 C CE2 . TYR B 2 192 ? 34.643 49.376 64.619 1.00 29.39 ? 192 TYR L CE2 1 ATOM 4571 C CZ . TYR B 2 192 ? 34.486 50.429 63.746 1.00 28.37 ? 192 TYR L CZ 1 ATOM 4572 O OH . TYR B 2 192 ? 35.347 50.588 62.666 1.00 26.05 ? 192 TYR L OH 1 ATOM 4573 N N . THR B 2 193 ? 29.597 47.511 67.808 1.00 36.26 ? 193 THR L N 1 ATOM 4574 C CA . THR B 2 193 ? 28.656 46.924 68.750 1.00 36.44 ? 193 THR L CA 1 ATOM 4575 C C . THR B 2 193 ? 29.376 45.990 69.715 1.00 36.68 ? 193 THR L C 1 ATOM 4576 O O . THR B 2 193 ? 30.378 45.357 69.368 1.00 39.20 ? 193 THR L O 1 ATOM 4577 C CB . THR B 2 193 ? 27.587 46.148 67.956 1.00 37.16 ? 193 THR L CB 1 ATOM 4578 O OG1 . THR B 2 193 ? 27.000 47.091 67.076 1.00 38.93 ? 193 THR L OG1 1 ATOM 4579 C CG2 . THR B 2 193 ? 26.521 45.508 68.810 1.00 37.70 ? 193 THR L CG2 1 ATOM 4580 N N . CYS B 2 194 ? 28.820 45.883 70.913 1.00 37.53 ? 194 CYS L N 1 ATOM 4581 C CA . CYS B 2 194 ? 29.291 45.059 72.013 1.00 36.18 ? 194 CYS L CA 1 ATOM 4582 C C . CYS B 2 194 ? 27.957 44.482 72.421 1.00 36.38 ? 194 CYS L C 1 ATOM 4583 O O . CYS B 2 194 ? 27.038 45.240 72.769 1.00 37.38 ? 194 CYS L O 1 ATOM 4584 C CB . CYS B 2 194 ? 29.868 45.951 73.131 1.00 33.84 ? 194 CYS L CB 1 ATOM 4585 S SG . CYS B 2 194 ? 30.305 45.207 74.726 1.00 31.20 ? 194 CYS L SG 1 ATOM 4586 N N . GLU B 2 195 ? 27.770 43.183 72.268 1.00 37.02 ? 195 GLU L N 1 ATOM 4587 C CA . GLU B 2 195 ? 26.547 42.559 72.732 1.00 38.34 ? 195 GLU L CA 1 ATOM 4588 C C . GLU B 2 195 ? 26.942 41.523 73.779 1.00 36.93 ? 195 GLU L C 1 ATOM 4589 O O . GLU B 2 195 ? 27.937 40.806 73.612 1.00 37.23 ? 195 GLU L O 1 ATOM 4590 C CB . GLU B 2 195 ? 25.837 41.911 71.555 1.00 43.12 ? 195 GLU L CB 1 ATOM 4591 C CG . GLU B 2 195 ? 24.873 40.765 71.867 1.00 47.70 ? 195 GLU L CG 1 ATOM 4592 C CD . GLU B 2 195 ? 25.173 39.480 71.092 1.00 50.22 ? 195 GLU L CD 1 ATOM 4593 O OE1 . GLU B 2 195 ? 26.305 38.967 71.160 1.00 52.62 ? 195 GLU L OE1 1 ATOM 4594 O OE2 . GLU B 2 195 ? 24.262 38.984 70.427 1.00 51.49 ? 195 GLU L OE2 1 ATOM 4595 N N . ALA B 2 196 ? 26.108 41.409 74.812 1.00 35.13 ? 196 ALA L N 1 ATOM 4596 C CA . ALA B 2 196 ? 26.335 40.552 75.946 1.00 34.10 ? 196 ALA L CA 1 ATOM 4597 C C . ALA B 2 196 ? 25.089 39.766 76.196 1.00 33.42 ? 196 ALA L C 1 ATOM 4598 O O . ALA B 2 196 ? 23.954 40.236 76.176 1.00 34.27 ? 196 ALA L O 1 ATOM 4599 C CB . ALA B 2 196 ? 26.628 41.353 77.200 1.00 34.06 ? 196 ALA L CB 1 ATOM 4600 N N . THR B 2 197 ? 25.316 38.501 76.342 1.00 34.68 ? 197 THR L N 1 ATOM 4601 C CA . THR B 2 197 ? 24.255 37.606 76.734 1.00 35.64 ? 197 THR L CA 1 ATOM 4602 C C . THR B 2 197 ? 24.583 37.233 78.188 1.00 35.42 ? 197 THR L C 1 ATOM 4603 O O . THR B 2 197 ? 25.739 36.949 78.537 1.00 35.91 ? 197 THR L O 1 ATOM 4604 C CB . THR B 2 197 ? 24.255 36.367 75.776 1.00 35.94 ? 197 THR L CB 1 ATOM 4605 O OG1 . THR B 2 197 ? 25.445 36.321 74.963 1.00 36.57 ? 197 THR L OG1 1 ATOM 4606 C CG2 . THR B 2 197 ? 23.021 36.446 74.887 1.00 36.50 ? 197 THR L CG2 1 ATOM 4607 N N . HIS B 2 198 ? 23.606 37.264 79.085 1.00 34.81 ? 198 HIS L N 1 ATOM 4608 C CA . HIS B 2 198 ? 23.824 36.899 80.476 1.00 35.81 ? 198 HIS L CA 1 ATOM 4609 C C . HIS B 2 198 ? 22.557 36.234 81.036 1.00 37.22 ? 198 HIS L C 1 ATOM 4610 O O . HIS B 2 198 ? 21.478 36.418 80.475 1.00 36.71 ? 198 HIS L O 1 ATOM 4611 C CB . HIS B 2 198 ? 24.136 38.144 81.292 1.00 36.08 ? 198 HIS L CB 1 ATOM 4612 C CG . HIS B 2 198 ? 24.749 37.776 82.626 1.00 36.11 ? 198 HIS L CG 1 ATOM 4613 N ND1 . HIS B 2 198 ? 24.186 37.577 83.809 1.00 36.24 ? 198 HIS L ND1 1 ATOM 4614 C CD2 . HIS B 2 198 ? 26.088 37.535 82.758 1.00 35.27 ? 198 HIS L CD2 1 ATOM 4615 C CE1 . HIS B 2 198 ? 25.143 37.231 84.628 1.00 36.74 ? 198 HIS L CE1 1 ATOM 4616 N NE2 . HIS B 2 198 ? 26.285 37.205 83.990 1.00 36.09 ? 198 HIS L NE2 1 ATOM 4617 N N . LYS B 2 199 ? 22.625 35.480 82.145 1.00 38.18 ? 199 LYS L N 1 ATOM 4618 C CA . LYS B 2 199 ? 21.457 34.900 82.796 1.00 39.21 ? 199 LYS L CA 1 ATOM 4619 C C . LYS B 2 199 ? 20.355 35.956 82.982 1.00 39.46 ? 199 LYS L C 1 ATOM 4620 O O . LYS B 2 199 ? 19.183 35.706 82.696 1.00 39.11 ? 199 LYS L O 1 ATOM 4621 C CB . LYS B 2 199 ? 21.906 34.333 84.135 1.00 39.58 ? 199 LYS L CB 1 ATOM 4622 C CG . LYS B 2 199 ? 20.803 33.556 84.802 1.00 40.40 ? 199 LYS L CG 1 ATOM 4623 C CD . LYS B 2 199 ? 21.254 33.225 86.189 1.00 42.27 ? 199 LYS L CD 1 ATOM 4624 C CE . LYS B 2 199 ? 20.141 32.585 87.006 1.00 44.05 ? 199 LYS L CE 1 ATOM 4625 N NZ . LYS B 2 199 ? 20.662 32.162 88.299 1.00 45.61 ? 199 LYS L NZ 1 ATOM 4626 N N . THR B 2 200 ? 20.735 37.171 83.375 1.00 40.09 ? 200 THR L N 1 ATOM 4627 C CA . THR B 2 200 ? 19.817 38.276 83.506 1.00 39.62 ? 200 THR L CA 1 ATOM 4628 C C . THR B 2 200 ? 18.923 38.614 82.298 1.00 41.21 ? 200 THR L C 1 ATOM 4629 O O . THR B 2 200 ? 18.008 39.438 82.457 1.00 43.66 ? 200 THR L O 1 ATOM 4630 C CB . THR B 2 200 ? 20.616 39.537 83.898 1.00 39.43 ? 200 THR L CB 1 ATOM 4631 O OG1 . THR B 2 200 ? 22.006 39.260 84.149 1.00 39.31 ? 200 THR L OG1 1 ATOM 4632 C CG2 . THR B 2 200 ? 19.936 40.103 85.126 1.00 39.50 ? 200 THR L CG2 1 ATOM 4633 N N . SER B 2 201 ? 19.131 38.098 81.079 1.00 40.34 ? 201 SER L N 1 ATOM 4634 C CA . SER B 2 201 ? 18.231 38.385 79.979 1.00 40.08 ? 201 SER L CA 1 ATOM 4635 C C . SER B 2 201 ? 18.552 37.486 78.824 1.00 40.43 ? 201 SER L C 1 ATOM 4636 O O . SER B 2 201 ? 19.671 37.275 78.337 1.00 42.07 ? 201 SER L O 1 ATOM 4637 C CB . SER B 2 201 ? 18.315 39.824 79.384 1.00 39.19 ? 201 SER L CB 1 ATOM 4638 O OG . SER B 2 201 ? 17.280 40.060 78.412 1.00 38.80 ? 201 SER L OG 1 ATOM 4639 N N . THR B 2 202 ? 17.364 37.123 78.395 1.00 41.34 ? 202 THR L N 1 ATOM 4640 C CA . THR B 2 202 ? 17.185 36.403 77.177 1.00 42.92 ? 202 THR L CA 1 ATOM 4641 C C . THR B 2 202 ? 17.581 37.286 75.988 1.00 42.25 ? 202 THR L C 1 ATOM 4642 O O . THR B 2 202 ? 18.387 36.912 75.136 1.00 43.15 ? 202 THR L O 1 ATOM 4643 C CB . THR B 2 202 ? 15.720 35.991 77.183 1.00 43.83 ? 202 THR L CB 1 ATOM 4644 O OG1 . THR B 2 202 ? 15.604 35.308 75.944 1.00 45.84 ? 202 THR L OG1 1 ATOM 4645 C CG2 . THR B 2 202 ? 14.679 37.130 77.381 1.00 43.39 ? 202 THR L CG2 1 ATOM 4646 N N . SER B 2 203 ? 17.034 38.487 75.916 1.00 41.79 ? 203 SER L N 1 ATOM 4647 C CA . SER B 2 203 ? 17.322 39.384 74.823 1.00 41.00 ? 203 SER L CA 1 ATOM 4648 C C . SER B 2 203 ? 18.725 39.916 75.102 1.00 40.62 ? 203 SER L C 1 ATOM 4649 O O . SER B 2 203 ? 18.948 40.441 76.204 1.00 42.38 ? 203 SER L O 1 ATOM 4650 C CB . SER B 2 203 ? 16.266 40.484 74.850 1.00 41.89 ? 203 SER L CB 1 ATOM 4651 O OG . SER B 2 203 ? 15.008 39.934 75.278 1.00 44.09 ? 203 SER L OG 1 ATOM 4652 N N . PRO B 2 204 ? 19.694 39.747 74.195 1.00 39.31 ? 204 PRO L N 1 ATOM 4653 C CA . PRO B 2 204 ? 20.935 40.506 74.146 1.00 37.85 ? 204 PRO L CA 1 ATOM 4654 C C . PRO B 2 204 ? 20.900 41.892 74.786 1.00 36.59 ? 204 PRO L C 1 ATOM 4655 O O . PRO B 2 204 ? 19.958 42.686 74.602 1.00 39.13 ? 204 PRO L O 1 ATOM 4656 C CB . PRO B 2 204 ? 21.231 40.523 72.674 1.00 37.99 ? 204 PRO L CB 1 ATOM 4657 C CG . PRO B 2 204 ? 20.922 39.106 72.288 1.00 38.25 ? 204 PRO L CG 1 ATOM 4658 C CD . PRO B 2 204 ? 19.620 38.851 73.045 1.00 38.67 ? 204 PRO L CD 1 ATOM 4659 N N . ILE B 2 205 ? 21.926 42.148 75.584 1.00 33.61 ? 205 ILE L N 1 ATOM 4660 C CA . ILE B 2 205 ? 22.110 43.418 76.246 1.00 31.26 ? 205 ILE L CA 1 ATOM 4661 C C . ILE B 2 205 ? 23.103 43.975 75.256 1.00 30.09 ? 205 ILE L C 1 ATOM 4662 O O . ILE B 2 205 ? 24.213 43.471 75.207 1.00 29.57 ? 205 ILE L O 1 ATOM 4663 C CB . ILE B 2 205 ? 22.654 43.110 77.679 1.00 31.43 ? 205 ILE L CB 1 ATOM 4664 C CG1 . ILE B 2 205 ? 21.621 42.267 78.501 1.00 30.78 ? 205 ILE L CG1 1 ATOM 4665 C CG2 . ILE B 2 205 ? 22.880 44.424 78.405 1.00 31.99 ? 205 ILE L CG2 1 ATOM 4666 C CD1 . ILE B 2 205 ? 22.147 41.260 79.570 1.00 30.68 ? 205 ILE L CD1 1 ATOM 4667 N N . VAL B 2 206 ? 22.743 44.947 74.421 1.00 30.14 ? 206 VAL L N 1 ATOM 4668 C CA . VAL B 2 206 ? 23.587 45.372 73.297 1.00 29.84 ? 206 VAL L CA 1 ATOM 4669 C C . VAL B 2 206 ? 23.943 46.860 73.331 1.00 30.61 ? 206 VAL L C 1 ATOM 4670 O O . VAL B 2 206 ? 23.034 47.682 73.463 1.00 32.05 ? 206 VAL L O 1 ATOM 4671 C CB . VAL B 2 206 ? 22.894 45.129 71.915 1.00 30.12 ? 206 VAL L CB 1 ATOM 4672 C CG1 . VAL B 2 206 ? 23.999 44.989 70.905 1.00 30.90 ? 206 VAL L CG1 1 ATOM 4673 C CG2 . VAL B 2 206 ? 22.006 43.898 71.859 1.00 29.37 ? 206 VAL L CG2 1 ATOM 4674 N N . LYS B 2 207 ? 25.195 47.286 73.208 1.00 28.52 ? 207 LYS L N 1 ATOM 4675 C CA . LYS B 2 207 ? 25.476 48.702 73.167 1.00 26.68 ? 207 LYS L CA 1 ATOM 4676 C C . LYS B 2 207 ? 26.165 48.943 71.845 1.00 25.48 ? 207 LYS L C 1 ATOM 4677 O O . LYS B 2 207 ? 27.065 48.193 71.464 1.00 25.06 ? 207 LYS L O 1 ATOM 4678 C CB . LYS B 2 207 ? 26.382 49.092 74.317 1.00 28.08 ? 207 LYS L CB 1 ATOM 4679 C CG . LYS B 2 207 ? 25.884 50.210 75.238 1.00 28.54 ? 207 LYS L CG 1 ATOM 4680 C CD . LYS B 2 207 ? 24.676 49.748 76.053 1.00 29.56 ? 207 LYS L CD 1 ATOM 4681 C CE . LYS B 2 207 ? 24.521 50.530 77.366 1.00 31.33 ? 207 LYS L CE 1 ATOM 4682 N NZ . LYS B 2 207 ? 24.364 51.977 77.254 1.00 32.81 ? 207 LYS L NZ 1 ATOM 4683 N N . SER B 2 208 ? 25.745 49.945 71.107 1.00 24.93 ? 208 SER L N 1 ATOM 4684 C CA . SER B 2 208 ? 26.323 50.260 69.820 1.00 25.23 ? 208 SER L CA 1 ATOM 4685 C C . SER B 2 208 ? 26.627 51.743 69.800 1.00 29.44 ? 208 SER L C 1 ATOM 4686 O O . SER B 2 208 ? 26.094 52.504 70.626 1.00 29.30 ? 208 SER L O 1 ATOM 4687 C CB . SER B 2 208 ? 25.343 49.983 68.712 1.00 22.84 ? 208 SER L CB 1 ATOM 4688 O OG . SER B 2 208 ? 24.628 48.768 68.940 1.00 24.36 ? 208 SER L OG 1 ATOM 4689 N N . PHE B 2 209 ? 27.480 52.190 68.875 1.00 33.10 ? 209 PHE L N 1 ATOM 4690 C CA . PHE B 2 209 ? 27.744 53.607 68.731 1.00 35.71 ? 209 PHE L CA 1 ATOM 4691 C C . PHE B 2 209 ? 28.242 53.860 67.311 1.00 37.99 ? 209 PHE L C 1 ATOM 4692 O O . PHE B 2 209 ? 28.801 52.960 66.677 1.00 37.46 ? 209 PHE L O 1 ATOM 4693 C CB . PHE B 2 209 ? 28.854 54.114 69.733 1.00 35.99 ? 209 PHE L CB 1 ATOM 4694 C CG . PHE B 2 209 ? 30.276 54.049 69.180 1.00 37.62 ? 209 PHE L CG 1 ATOM 4695 C CD1 . PHE B 2 209 ? 30.961 52.847 69.170 1.00 38.24 ? 209 PHE L CD1 1 ATOM 4696 C CD2 . PHE B 2 209 ? 30.831 55.168 68.578 1.00 37.30 ? 209 PHE L CD2 1 ATOM 4697 C CE1 . PHE B 2 209 ? 32.184 52.787 68.535 1.00 39.86 ? 209 PHE L CE1 1 ATOM 4698 C CE2 . PHE B 2 209 ? 32.048 55.096 67.941 1.00 37.58 ? 209 PHE L CE2 1 ATOM 4699 C CZ . PHE B 2 209 ? 32.726 53.901 67.921 1.00 39.27 ? 209 PHE L CZ 1 ATOM 4700 N N . ASN B 2 210 ? 27.958 55.056 66.810 1.00 41.46 ? 210 ASN L N 1 ATOM 4701 C CA . ASN B 2 210 ? 28.889 55.709 65.907 1.00 43.42 ? 210 ASN L CA 1 ATOM 4702 C C . ASN B 2 210 ? 28.800 57.158 66.431 1.00 44.09 ? 210 ASN L C 1 ATOM 4703 O O . ASN B 2 210 ? 27.831 57.543 67.126 1.00 44.61 ? 210 ASN L O 1 ATOM 4704 C CB . ASN B 2 210 ? 28.559 55.713 64.414 1.00 44.43 ? 210 ASN L CB 1 ATOM 4705 C CG . ASN B 2 210 ? 29.900 56.133 63.763 1.00 45.88 ? 210 ASN L CG 1 ATOM 4706 O OD1 . ASN B 2 210 ? 30.175 57.320 63.580 1.00 46.69 ? 210 ASN L OD1 1 ATOM 4707 N ND2 . ASN B 2 210 ? 30.891 55.289 63.498 1.00 46.28 ? 210 ASN L ND2 1 ATOM 4708 N N . ARG B 2 211 ? 29.831 57.975 66.206 1.00 43.41 ? 211 ARG L N 1 ATOM 4709 C CA . ARG B 2 211 ? 29.942 59.318 66.765 1.00 43.21 ? 211 ARG L CA 1 ATOM 4710 C C . ARG B 2 211 ? 28.798 60.269 66.444 1.00 43.64 ? 211 ARG L C 1 ATOM 4711 O O . ARG B 2 211 ? 28.369 60.400 65.297 1.00 43.64 ? 211 ARG L O 1 ATOM 4712 C CB . ARG B 2 211 ? 31.236 59.977 66.290 1.00 42.50 ? 211 ARG L CB 1 ATOM 4713 C CG . ARG B 2 211 ? 32.547 59.318 66.711 1.00 41.89 ? 211 ARG L CG 1 ATOM 4714 C CD . ARG B 2 211 ? 33.742 60.079 66.133 1.00 41.43 ? 211 ARG L CD 1 ATOM 4715 N NE . ARG B 2 211 ? 33.852 61.434 66.662 1.00 40.95 ? 211 ARG L NE 1 ATOM 4716 C CZ . ARG B 2 211 ? 34.272 62.465 65.918 1.00 40.70 ? 211 ARG L CZ 1 ATOM 4717 N NH1 . ARG B 2 211 ? 34.618 62.319 64.639 1.00 40.44 ? 211 ARG L NH1 1 ATOM 4718 N NH2 . ARG B 2 211 ? 34.353 63.676 66.463 1.00 40.58 ? 211 ARG L NH2 1 ATOM 4719 N N . ASN B 2 212 ? 28.287 60.952 67.463 1.00 44.43 ? 212 ASN L N 1 ATOM 4720 C CA . ASN B 2 212 ? 27.245 61.954 67.288 1.00 45.24 ? 212 ASN L CA 1 ATOM 4721 C C . ASN B 2 212 ? 27.345 62.878 68.496 1.00 45.66 ? 212 ASN L C 1 ATOM 4722 O O . ASN B 2 212 ? 28.067 62.541 69.442 1.00 45.71 ? 212 ASN L O 1 ATOM 4723 C CB . ASN B 2 212 ? 25.854 61.313 67.253 1.00 45.46 ? 212 ASN L CB 1 ATOM 4724 C CG . ASN B 2 212 ? 24.844 62.171 66.502 1.00 45.66 ? 212 ASN L CG 1 ATOM 4725 O OD1 . ASN B 2 212 ? 24.741 63.384 66.670 1.00 45.76 ? 212 ASN L OD1 1 ATOM 4726 N ND2 . ASN B 2 212 ? 24.061 61.608 65.595 1.00 45.70 ? 212 ASN L ND2 1 ATOM 4727 N N . GLU B 2 213 ? 26.715 64.053 68.482 1.00 46.16 ? 213 GLU L N 1 ATOM 4728 C CA . GLU B 2 213 ? 26.769 64.972 69.609 1.00 46.64 ? 213 GLU L CA 1 ATOM 4729 C C . GLU B 2 213 ? 25.632 64.623 70.551 1.00 46.52 ? 213 GLU L C 1 ATOM 4730 O O . GLU B 2 213 ? 24.719 63.875 70.170 1.00 46.73 ? 213 GLU L O 1 ATOM 4731 C CB . GLU B 2 213 ? 26.600 66.427 69.167 1.00 47.13 ? 213 GLU L CB 1 ATOM 4732 C CG . GLU B 2 213 ? 27.746 67.031 68.361 1.00 47.78 ? 213 GLU L CG 1 ATOM 4733 C CD . GLU B 2 213 ? 27.834 66.556 66.918 1.00 48.13 ? 213 GLU L CD 1 ATOM 4734 O OE1 . GLU B 2 213 ? 27.057 67.036 66.094 1.00 48.38 ? 213 GLU L OE1 1 ATOM 4735 O OE2 . GLU B 2 213 ? 28.679 65.713 66.621 1.00 48.36 ? 213 GLU L OE2 1 ATOM 4736 N N . CYS B 2 214 ? 25.643 65.197 71.746 1.00 46.15 ? 214 CYS L N 1 ATOM 4737 C CA . CYS B 2 214 ? 24.637 64.896 72.743 1.00 45.73 ? 214 CYS L CA 1 ATOM 4738 C C . CYS B 2 214 ? 24.218 66.147 73.517 1.00 45.86 ? 214 CYS L C 1 ATOM 4739 O O . CYS B 2 214 ? 23.253 66.073 74.273 1.00 46.02 ? 214 CYS L O 1 ATOM 4740 C CB . CYS B 2 214 ? 25.213 63.841 73.677 1.00 45.07 ? 214 CYS L CB 1 ATOM 4741 S SG . CYS B 2 214 ? 25.837 62.341 72.860 1.00 44.29 ? 214 CYS L SG 1 ATOM 4742 O OXT . CYS B 2 214 ? 24.846 67.196 73.354 1.00 46.02 ? 214 CYS L OXT 1 ATOM 4743 N N . GLN C 3 1 ? 53.703 45.914 114.493 1.00 35.96 ? 1 GLN H N 1 ATOM 4744 C CA . GLN C 3 1 ? 53.850 44.768 115.371 1.00 36.14 ? 1 GLN H CA 1 ATOM 4745 C C . GLN C 3 1 ? 54.787 43.927 114.517 1.00 32.85 ? 1 GLN H C 1 ATOM 4746 O O . GLN C 3 1 ? 55.815 44.535 114.206 1.00 35.00 ? 1 GLN H O 1 ATOM 4747 C CB . GLN C 3 1 ? 52.469 44.110 115.611 1.00 39.91 ? 1 GLN H CB 1 ATOM 4748 C CG . GLN C 3 1 ? 52.351 43.108 116.801 1.00 44.20 ? 1 GLN H CG 1 ATOM 4749 C CD . GLN C 3 1 ? 52.810 43.593 118.191 1.00 46.66 ? 1 GLN H CD 1 ATOM 4750 O OE1 . GLN C 3 1 ? 53.826 44.279 118.319 1.00 48.46 ? 1 GLN H OE1 1 ATOM 4751 N NE2 . GLN C 3 1 ? 52.147 43.246 119.293 1.00 46.58 ? 1 GLN H NE2 1 ATOM 4752 N N . ILE C 3 2 ? 54.592 42.684 114.059 1.00 28.31 ? 2 ILE H N 1 ATOM 4753 C CA . ILE C 3 2 ? 55.585 42.086 113.187 1.00 23.01 ? 2 ILE H CA 1 ATOM 4754 C C . ILE C 3 2 ? 55.241 42.680 111.818 1.00 23.75 ? 2 ILE H C 1 ATOM 4755 O O . ILE C 3 2 ? 54.052 42.807 111.503 1.00 26.83 ? 2 ILE H O 1 ATOM 4756 C CB . ILE C 3 2 ? 55.452 40.545 113.201 1.00 17.30 ? 2 ILE H CB 1 ATOM 4757 C CG1 . ILE C 3 2 ? 55.904 39.979 114.516 1.00 16.14 ? 2 ILE H CG1 1 ATOM 4758 C CG2 . ILE C 3 2 ? 56.392 39.925 112.203 1.00 16.23 ? 2 ILE H CG2 1 ATOM 4759 C CD1 . ILE C 3 2 ? 54.775 39.858 115.545 1.00 12.76 ? 2 ILE H CD1 1 ATOM 4760 N N . GLN C 3 3 ? 56.199 43.162 111.026 1.00 23.54 ? 3 GLN H N 1 ATOM 4761 C CA . GLN C 3 3 ? 55.927 43.668 109.693 1.00 21.84 ? 3 GLN H CA 1 ATOM 4762 C C . GLN C 3 3 ? 57.096 43.170 108.883 1.00 19.49 ? 3 GLN H C 1 ATOM 4763 O O . GLN C 3 3 ? 58.216 43.463 109.282 1.00 21.20 ? 3 GLN H O 1 ATOM 4764 C CB . GLN C 3 3 ? 55.936 45.220 109.571 1.00 24.73 ? 3 GLN H CB 1 ATOM 4765 C CG . GLN C 3 3 ? 55.137 46.192 110.458 1.00 27.97 ? 3 GLN H CG 1 ATOM 4766 C CD . GLN C 3 3 ? 53.638 45.925 110.649 1.00 31.43 ? 3 GLN H CD 1 ATOM 4767 O OE1 . GLN C 3 3 ? 53.131 46.038 111.778 1.00 35.28 ? 3 GLN H OE1 1 ATOM 4768 N NE2 . GLN C 3 3 ? 52.811 45.570 109.681 1.00 31.39 ? 3 GLN H NE2 1 ATOM 4769 N N . LEU C 3 4 ? 56.960 42.411 107.803 1.00 17.25 ? 4 LEU H N 1 ATOM 4770 C CA . LEU C 3 4 ? 58.129 42.047 107.007 1.00 18.00 ? 4 LEU H CA 1 ATOM 4771 C C . LEU C 3 4 ? 57.863 42.607 105.632 1.00 18.74 ? 4 LEU H C 1 ATOM 4772 O O . LEU C 3 4 ? 57.023 42.082 104.883 1.00 20.57 ? 4 LEU H O 1 ATOM 4773 C CB . LEU C 3 4 ? 58.306 40.539 106.885 1.00 18.15 ? 4 LEU H CB 1 ATOM 4774 C CG . LEU C 3 4 ? 58.221 39.678 108.168 1.00 17.43 ? 4 LEU H CG 1 ATOM 4775 C CD1 . LEU C 3 4 ? 58.251 38.188 107.792 1.00 17.37 ? 4 LEU H CD1 1 ATOM 4776 C CD2 . LEU C 3 4 ? 59.327 40.094 109.136 1.00 17.72 ? 4 LEU H CD2 1 ATOM 4777 N N . VAL C 3 5 ? 58.461 43.773 105.364 1.00 20.87 ? 5 VAL H N 1 ATOM 4778 C CA . VAL C 3 5 ? 58.357 44.459 104.073 1.00 21.71 ? 5 VAL H CA 1 ATOM 4779 C C . VAL C 3 5 ? 59.512 43.906 103.224 1.00 21.63 ? 5 VAL H C 1 ATOM 4780 O O . VAL C 3 5 ? 60.592 43.642 103.779 1.00 22.92 ? 5 VAL H O 1 ATOM 4781 C CB . VAL C 3 5 ? 58.401 46.048 104.375 1.00 24.17 ? 5 VAL H CB 1 ATOM 4782 C CG1 . VAL C 3 5 ? 59.576 46.494 105.239 1.00 25.32 ? 5 VAL H CG1 1 ATOM 4783 C CG2 . VAL C 3 5 ? 58.601 46.807 103.067 1.00 24.06 ? 5 VAL H CG2 1 ATOM 4784 N N . GLN C 3 6 ? 59.339 43.707 101.914 1.00 22.02 ? 6 GLN H N 1 ATOM 4785 C CA . GLN C 3 6 ? 60.316 43.033 101.059 1.00 21.75 ? 6 GLN H CA 1 ATOM 4786 C C . GLN C 3 6 ? 60.844 43.919 99.937 1.00 24.53 ? 6 GLN H C 1 ATOM 4787 O O . GLN C 3 6 ? 60.571 45.138 99.925 1.00 26.20 ? 6 GLN H O 1 ATOM 4788 C CB . GLN C 3 6 ? 59.708 41.817 100.428 1.00 20.57 ? 6 GLN H CB 1 ATOM 4789 C CG . GLN C 3 6 ? 59.201 40.781 101.397 1.00 18.84 ? 6 GLN H CG 1 ATOM 4790 C CD . GLN C 3 6 ? 58.583 39.609 100.668 1.00 18.74 ? 6 GLN H CD 1 ATOM 4791 O OE1 . GLN C 3 6 ? 58.853 39.316 99.526 1.00 19.02 ? 6 GLN H OE1 1 ATOM 4792 N NE2 . GLN C 3 6 ? 57.677 38.837 101.208 1.00 19.32 ? 6 GLN H NE2 1 ATOM 4793 N N . SER C 3 7 ? 61.662 43.436 99.001 1.00 26.19 ? 7 SER H N 1 ATOM 4794 C CA . SER C 3 7 ? 62.065 44.314 97.928 1.00 29.02 ? 7 SER H CA 1 ATOM 4795 C C . SER C 3 7 ? 60.906 44.504 96.923 1.00 29.73 ? 7 SER H C 1 ATOM 4796 O O . SER C 3 7 ? 59.900 43.787 96.964 1.00 30.38 ? 7 SER H O 1 ATOM 4797 C CB . SER C 3 7 ? 63.320 43.701 97.306 1.00 28.24 ? 7 SER H CB 1 ATOM 4798 O OG . SER C 3 7 ? 63.242 42.296 97.104 1.00 29.86 ? 7 SER H OG 1 ATOM 4799 N N . GLY C 3 8 ? 60.974 45.482 96.009 1.00 32.22 ? 8 GLY H N 1 ATOM 4800 C CA . GLY C 3 8 ? 59.953 45.703 94.998 1.00 33.23 ? 8 GLY H CA 1 ATOM 4801 C C . GLY C 3 8 ? 60.088 44.686 93.876 1.00 34.70 ? 8 GLY H C 1 ATOM 4802 O O . GLY C 3 8 ? 61.106 43.991 93.835 1.00 35.84 ? 8 GLY H O 1 ATOM 4803 N N . PRO C 3 9 ? 59.129 44.517 92.965 1.00 34.88 ? 9 PRO H N 1 ATOM 4804 C CA . PRO C 3 9 ? 59.161 43.494 91.916 1.00 36.33 ? 9 PRO H CA 1 ATOM 4805 C C . PRO C 3 9 ? 60.387 43.510 90.974 1.00 37.57 ? 9 PRO H C 1 ATOM 4806 O O . PRO C 3 9 ? 60.927 44.602 90.722 1.00 41.43 ? 9 PRO H O 1 ATOM 4807 C CB . PRO C 3 9 ? 57.824 43.734 91.237 1.00 35.84 ? 9 PRO H CB 1 ATOM 4808 C CG . PRO C 3 9 ? 57.627 45.229 91.327 1.00 34.68 ? 9 PRO H CG 1 ATOM 4809 C CD . PRO C 3 9 ? 58.022 45.442 92.769 1.00 35.16 ? 9 PRO H CD 1 ATOM 4810 N N . GLU C 3 10 ? 60.853 42.415 90.359 1.00 35.11 ? 10 GLU H N 1 ATOM 4811 C CA . GLU C 3 10 ? 62.049 42.518 89.540 1.00 33.03 ? 10 GLU H CA 1 ATOM 4812 C C . GLU C 3 10 ? 61.951 41.851 88.180 1.00 30.32 ? 10 GLU H C 1 ATOM 4813 O O . GLU C 3 10 ? 61.360 40.771 88.029 1.00 29.31 ? 10 GLU H O 1 ATOM 4814 C CB . GLU C 3 10 ? 63.234 41.957 90.319 1.00 35.20 ? 10 GLU H CB 1 ATOM 4815 C CG . GLU C 3 10 ? 64.135 43.146 90.638 1.00 40.15 ? 10 GLU H CG 1 ATOM 4816 C CD . GLU C 3 10 ? 65.142 42.906 91.760 1.00 44.53 ? 10 GLU H CD 1 ATOM 4817 O OE1 . GLU C 3 10 ? 64.724 42.545 92.874 1.00 46.66 ? 10 GLU H OE1 1 ATOM 4818 O OE2 . GLU C 3 10 ? 66.339 43.095 91.525 1.00 46.81 ? 10 GLU H OE2 1 ATOM 4819 N N . LEU C 3 11 ? 62.510 42.572 87.197 1.00 25.41 ? 11 LEU H N 1 ATOM 4820 C CA . LEU C 3 11 ? 62.517 42.151 85.812 1.00 23.05 ? 11 LEU H CA 1 ATOM 4821 C C . LEU C 3 11 ? 63.943 41.751 85.594 1.00 22.82 ? 11 LEU H C 1 ATOM 4822 O O . LEU C 3 11 ? 64.842 42.511 85.953 1.00 21.39 ? 11 LEU H O 1 ATOM 4823 C CB . LEU C 3 11 ? 62.181 43.316 84.856 1.00 21.65 ? 11 LEU H CB 1 ATOM 4824 C CG . LEU C 3 11 ? 62.011 43.135 83.309 1.00 20.82 ? 11 LEU H CG 1 ATOM 4825 C CD1 . LEU C 3 11 ? 60.753 42.332 82.991 1.00 18.19 ? 11 LEU H CD1 1 ATOM 4826 C CD2 . LEU C 3 11 ? 61.904 44.504 82.641 1.00 17.54 ? 11 LEU H CD2 1 ATOM 4827 N N . LYS C 3 12 ? 64.154 40.583 85.017 1.00 23.22 ? 12 LYS H N 1 ATOM 4828 C CA . LYS C 3 12 ? 65.485 40.086 84.732 1.00 25.11 ? 12 LYS H CA 1 ATOM 4829 C C . LYS C 3 12 ? 65.339 39.036 83.647 1.00 23.49 ? 12 LYS H C 1 ATOM 4830 O O . LYS C 3 12 ? 64.583 38.056 83.712 1.00 21.93 ? 12 LYS H O 1 ATOM 4831 C CB . LYS C 3 12 ? 66.177 39.354 85.887 1.00 26.84 ? 12 LYS H CB 1 ATOM 4832 C CG . LYS C 3 12 ? 66.608 39.982 87.212 1.00 28.80 ? 12 LYS H CG 1 ATOM 4833 C CD . LYS C 3 12 ? 67.752 40.972 87.049 1.00 30.35 ? 12 LYS H CD 1 ATOM 4834 C CE . LYS C 3 12 ? 68.018 41.639 88.384 1.00 31.22 ? 12 LYS H CE 1 ATOM 4835 N NZ . LYS C 3 12 ? 68.039 43.082 88.239 1.00 34.48 ? 12 LYS H NZ 1 ATOM 4836 N N . LYS C 3 13 ? 66.128 39.327 82.632 1.00 23.51 ? 13 LYS H N 1 ATOM 4837 C CA . LYS C 3 13 ? 66.336 38.500 81.463 1.00 24.13 ? 13 LYS H CA 1 ATOM 4838 C C . LYS C 3 13 ? 66.962 37.202 81.930 1.00 25.00 ? 13 LYS H C 1 ATOM 4839 O O . LYS C 3 13 ? 67.772 37.265 82.852 1.00 23.76 ? 13 LYS H O 1 ATOM 4840 C CB . LYS C 3 13 ? 67.261 39.246 80.515 1.00 23.17 ? 13 LYS H CB 1 ATOM 4841 C CG . LYS C 3 13 ? 67.492 38.640 79.146 1.00 22.26 ? 13 LYS H CG 1 ATOM 4842 C CD . LYS C 3 13 ? 68.585 39.466 78.508 1.00 21.58 ? 13 LYS H CD 1 ATOM 4843 C CE . LYS C 3 13 ? 68.688 39.151 77.033 1.00 21.18 ? 13 LYS H CE 1 ATOM 4844 N NZ . LYS C 3 13 ? 69.734 39.965 76.456 1.00 20.21 ? 13 LYS H NZ 1 ATOM 4845 N N . PRO C 3 14 ? 66.539 36.051 81.369 1.00 26.99 ? 14 PRO H N 1 ATOM 4846 C CA . PRO C 3 14 ? 67.068 34.712 81.557 1.00 28.43 ? 14 PRO H CA 1 ATOM 4847 C C . PRO C 3 14 ? 68.523 34.531 81.912 1.00 30.69 ? 14 PRO H C 1 ATOM 4848 O O . PRO C 3 14 ? 69.389 35.285 81.469 1.00 31.57 ? 14 PRO H O 1 ATOM 4849 C CB . PRO C 3 14 ? 66.677 34.025 80.271 1.00 27.98 ? 14 PRO H CB 1 ATOM 4850 C CG . PRO C 3 14 ? 65.236 34.435 80.188 1.00 27.65 ? 14 PRO H CG 1 ATOM 4851 C CD . PRO C 3 14 ? 65.299 35.913 80.602 1.00 27.29 ? 14 PRO H CD 1 ATOM 4852 N N . GLY C 3 15 ? 68.769 33.518 82.745 1.00 32.72 ? 15 GLY H N 1 ATOM 4853 C CA . GLY C 3 15 ? 70.110 33.254 83.210 1.00 34.04 ? 15 GLY H CA 1 ATOM 4854 C C . GLY C 3 15 ? 70.676 34.336 84.129 1.00 34.48 ? 15 GLY H C 1 ATOM 4855 O O . GLY C 3 15 ? 71.819 34.191 84.562 1.00 34.41 ? 15 GLY H O 1 ATOM 4856 N N . GLU C 3 16 ? 69.957 35.385 84.532 1.00 35.10 ? 16 GLU H N 1 ATOM 4857 C CA . GLU C 3 16 ? 70.520 36.396 85.411 1.00 36.34 ? 16 GLU H CA 1 ATOM 4858 C C . GLU C 3 16 ? 70.457 35.999 86.878 1.00 35.72 ? 16 GLU H C 1 ATOM 4859 O O . GLU C 3 16 ? 70.126 34.851 87.173 1.00 35.17 ? 16 GLU H O 1 ATOM 4860 C CB . GLU C 3 16 ? 69.806 37.712 85.215 1.00 40.46 ? 16 GLU H CB 1 ATOM 4861 C CG . GLU C 3 16 ? 70.400 38.501 84.059 1.00 44.32 ? 16 GLU H CG 1 ATOM 4862 C CD . GLU C 3 16 ? 69.926 39.940 83.975 1.00 45.88 ? 16 GLU H CD 1 ATOM 4863 O OE1 . GLU C 3 16 ? 70.565 40.786 84.603 1.00 47.06 ? 16 GLU H OE1 1 ATOM 4864 O OE2 . GLU C 3 16 ? 68.940 40.204 83.286 1.00 48.24 ? 16 GLU H OE2 1 ATOM 4865 N N . THR C 3 17 ? 70.736 36.908 87.820 1.00 34.59 ? 17 THR H N 1 ATOM 4866 C CA . THR C 3 17 ? 70.837 36.597 89.240 1.00 34.33 ? 17 THR H CA 1 ATOM 4867 C C . THR C 3 17 ? 70.087 37.659 90.019 1.00 33.46 ? 17 THR H C 1 ATOM 4868 O O . THR C 3 17 ? 70.259 38.852 89.715 1.00 34.33 ? 17 THR H O 1 ATOM 4869 C CB . THR C 3 17 ? 72.318 36.598 89.671 1.00 34.07 ? 17 THR H CB 1 ATOM 4870 O OG1 . THR C 3 17 ? 72.958 35.616 88.833 1.00 34.93 ? 17 THR H OG1 1 ATOM 4871 C CG2 . THR C 3 17 ? 72.507 36.390 91.191 1.00 33.25 ? 17 THR H CG2 1 ATOM 4872 N N . VAL C 3 18 ? 69.300 37.282 91.028 1.00 32.87 ? 18 VAL H N 1 ATOM 4873 C CA . VAL C 3 18 ? 68.590 38.298 91.780 1.00 30.71 ? 18 VAL H CA 1 ATOM 4874 C C . VAL C 3 18 ? 68.671 38.069 93.295 1.00 28.88 ? 18 VAL H C 1 ATOM 4875 O O . VAL C 3 18 ? 68.666 36.914 93.748 1.00 28.98 ? 18 VAL H O 1 ATOM 4876 C CB . VAL C 3 18 ? 67.159 38.300 91.186 1.00 30.62 ? 18 VAL H CB 1 ATOM 4877 C CG1 . VAL C 3 18 ? 66.418 37.015 91.467 1.00 30.44 ? 18 VAL H CG1 1 ATOM 4878 C CG2 . VAL C 3 18 ? 66.488 39.551 91.699 1.00 32.47 ? 18 VAL H CG2 1 ATOM 4879 N N . LYS C 3 19 ? 68.864 39.131 94.086 1.00 26.39 ? 19 LYS H N 1 ATOM 4880 C CA . LYS C 3 19 ? 68.880 39.041 95.536 1.00 24.37 ? 19 LYS H CA 1 ATOM 4881 C C . LYS C 3 19 ? 67.615 39.823 95.950 1.00 24.78 ? 19 LYS H C 1 ATOM 4882 O O . LYS C 3 19 ? 67.590 41.043 95.730 1.00 25.60 ? 19 LYS H O 1 ATOM 4883 C CB . LYS C 3 19 ? 70.163 39.693 96.057 1.00 23.83 ? 19 LYS H CB 1 ATOM 4884 C CG . LYS C 3 19 ? 70.482 39.364 97.501 1.00 23.00 ? 19 LYS H CG 1 ATOM 4885 C CD . LYS C 3 19 ? 71.901 39.786 97.859 1.00 22.45 ? 19 LYS H CD 1 ATOM 4886 C CE . LYS C 3 19 ? 72.221 39.212 99.227 1.00 22.10 ? 19 LYS H CE 1 ATOM 4887 N NZ . LYS C 3 19 ? 73.592 39.469 99.623 1.00 21.74 ? 19 LYS H NZ 1 ATOM 4888 N N . ILE C 3 20 ? 66.552 39.103 96.423 1.00 22.82 ? 20 ILE H N 1 ATOM 4889 C CA . ILE C 3 20 ? 65.249 39.555 96.977 1.00 18.21 ? 20 ILE H CA 1 ATOM 4890 C C . ILE C 3 20 ? 65.451 39.691 98.503 1.00 18.21 ? 20 ILE H C 1 ATOM 4891 O O . ILE C 3 20 ? 65.665 38.670 99.179 1.00 18.22 ? 20 ILE H O 1 ATOM 4892 C CB . ILE C 3 20 ? 64.124 38.473 96.659 1.00 18.31 ? 20 ILE H CB 1 ATOM 4893 C CG1 . ILE C 3 20 ? 63.910 38.393 95.162 1.00 18.38 ? 20 ILE H CG1 1 ATOM 4894 C CG2 . ILE C 3 20 ? 62.783 38.813 97.309 1.00 15.61 ? 20 ILE H CG2 1 ATOM 4895 C CD1 . ILE C 3 20 ? 62.954 37.256 94.776 1.00 16.73 ? 20 ILE H CD1 1 ATOM 4896 N N . SER C 3 21 ? 65.435 40.907 99.070 1.00 18.17 ? 21 SER H N 1 ATOM 4897 C CA . SER C 3 21 ? 65.617 41.194 100.503 1.00 18.93 ? 21 SER H CA 1 ATOM 4898 C C . SER C 3 21 ? 64.325 41.163 101.299 1.00 19.22 ? 21 SER H C 1 ATOM 4899 O O . SER C 3 21 ? 63.316 41.600 100.718 1.00 20.34 ? 21 SER H O 1 ATOM 4900 C CB . SER C 3 21 ? 66.206 42.582 100.727 1.00 20.10 ? 21 SER H CB 1 ATOM 4901 O OG . SER C 3 21 ? 67.494 42.771 100.135 1.00 24.11 ? 21 SER H OG 1 ATOM 4902 N N . CYS C 3 22 ? 64.348 40.763 102.601 1.00 16.35 ? 22 CYS H N 1 ATOM 4903 C CA . CYS C 3 22 ? 63.176 40.765 103.494 1.00 15.29 ? 22 CYS H CA 1 ATOM 4904 C C . CYS C 3 22 ? 63.597 41.202 104.892 1.00 14.40 ? 22 CYS H C 1 ATOM 4905 O O . CYS C 3 22 ? 64.384 40.531 105.544 1.00 12.97 ? 22 CYS H O 1 ATOM 4906 C CB . CYS C 3 22 ? 62.534 39.353 103.542 1.00 14.40 ? 22 CYS H CB 1 ATOM 4907 S SG . CYS C 3 22 ? 61.146 39.084 104.690 1.00 18.14 ? 22 CYS H SG 1 ATOM 4908 N N . LYS C 3 23 ? 63.130 42.399 105.280 1.00 15.37 ? 23 LYS H N 1 ATOM 4909 C CA . LYS C 3 23 ? 63.431 43.128 106.512 1.00 16.83 ? 23 LYS H CA 1 ATOM 4910 C C . LYS C 3 23 ? 62.334 43.001 107.576 1.00 18.29 ? 23 LYS H C 1 ATOM 4911 O O . LYS C 3 23 ? 61.164 43.421 107.437 1.00 17.98 ? 23 LYS H O 1 ATOM 4912 C CB . LYS C 3 23 ? 63.622 44.611 106.224 1.00 15.89 ? 23 LYS H CB 1 ATOM 4913 C CG . LYS C 3 23 ? 64.667 44.908 105.172 1.00 15.36 ? 23 LYS H CG 1 ATOM 4914 C CD . LYS C 3 23 ? 64.821 46.406 104.989 1.00 15.18 ? 23 LYS H CD 1 ATOM 4915 C CE . LYS C 3 23 ? 65.868 46.626 103.917 1.00 14.97 ? 23 LYS H CE 1 ATOM 4916 N NZ . LYS C 3 23 ? 66.175 48.034 103.766 1.00 14.98 ? 23 LYS H NZ 1 ATOM 4917 N N . ALA C 3 24 ? 62.804 42.387 108.661 1.00 21.63 ? 24 ALA H N 1 ATOM 4918 C CA . ALA C 3 24 ? 61.998 42.088 109.808 1.00 23.64 ? 24 ALA H CA 1 ATOM 4919 C C . ALA C 3 24 ? 61.900 43.228 110.823 1.00 24.42 ? 24 ALA H C 1 ATOM 4920 O O . ALA C 3 24 ? 62.813 44.050 110.970 1.00 23.19 ? 24 ALA H O 1 ATOM 4921 C CB . ALA C 3 24 ? 62.589 40.846 110.465 1.00 23.40 ? 24 ALA H CB 1 ATOM 4922 N N . SER C 3 25 ? 60.766 43.312 111.532 1.00 25.48 ? 25 SER H N 1 ATOM 4923 C CA . SER C 3 25 ? 60.599 44.234 112.636 1.00 25.52 ? 25 SER H CA 1 ATOM 4924 C C . SER C 3 25 ? 59.495 43.617 113.502 1.00 25.68 ? 25 SER H C 1 ATOM 4925 O O . SER C 3 25 ? 58.708 42.746 113.090 1.00 24.63 ? 25 SER H O 1 ATOM 4926 C CB . SER C 3 25 ? 60.175 45.579 112.128 1.00 27.61 ? 25 SER H CB 1 ATOM 4927 O OG . SER C 3 25 ? 58.933 45.376 111.494 1.00 32.72 ? 25 SER H OG 1 ATOM 4928 N N . GLY C 3 26 ? 59.475 44.051 114.754 1.00 24.90 ? 26 GLY H N 1 ATOM 4929 C CA . GLY C 3 26 ? 58.535 43.595 115.752 1.00 26.05 ? 26 GLY H CA 1 ATOM 4930 C C . GLY C 3 26 ? 59.142 42.544 116.656 1.00 25.89 ? 26 GLY H C 1 ATOM 4931 O O . GLY C 3 26 ? 59.009 42.612 117.876 1.00 26.84 ? 26 GLY H O 1 ATOM 4932 N N . TYR C 3 27 ? 59.856 41.578 116.101 1.00 25.66 ? 27 TYR H N 1 ATOM 4933 C CA . TYR C 3 27 ? 60.315 40.460 116.910 1.00 24.62 ? 27 TYR H CA 1 ATOM 4934 C C . TYR C 3 27 ? 61.828 40.456 117.082 1.00 26.11 ? 27 TYR H C 1 ATOM 4935 O O . TYR C 3 27 ? 62.503 41.364 116.586 1.00 27.12 ? 27 TYR H O 1 ATOM 4936 C CB . TYR C 3 27 ? 59.755 39.164 116.237 1.00 24.47 ? 27 TYR H CB 1 ATOM 4937 C CG . TYR C 3 27 ? 60.299 38.711 114.873 1.00 22.11 ? 27 TYR H CG 1 ATOM 4938 C CD1 . TYR C 3 27 ? 61.503 38.033 114.872 1.00 21.39 ? 27 TYR H CD1 1 ATOM 4939 C CD2 . TYR C 3 27 ? 59.614 38.902 113.675 1.00 21.23 ? 27 TYR H CD2 1 ATOM 4940 C CE1 . TYR C 3 27 ? 62.034 37.544 113.702 1.00 20.94 ? 27 TYR H CE1 1 ATOM 4941 C CE2 . TYR C 3 27 ? 60.168 38.399 112.493 1.00 23.15 ? 27 TYR H CE2 1 ATOM 4942 C CZ . TYR C 3 27 ? 61.380 37.718 112.510 1.00 19.92 ? 27 TYR H CZ 1 ATOM 4943 O OH . TYR C 3 27 ? 61.989 37.209 111.376 1.00 18.60 ? 27 TYR H OH 1 ATOM 4944 N N . THR C 3 28 ? 62.416 39.481 117.765 1.00 27.53 ? 28 THR H N 1 ATOM 4945 C CA . THR C 3 28 ? 63.854 39.444 117.925 1.00 28.37 ? 28 THR H CA 1 ATOM 4946 C C . THR C 3 28 ? 64.316 38.482 116.862 1.00 28.98 ? 28 THR H C 1 ATOM 4947 O O . THR C 3 28 ? 64.083 37.287 116.997 1.00 30.23 ? 28 THR H O 1 ATOM 4948 C CB . THR C 3 28 ? 64.172 38.990 119.385 1.00 30.07 ? 28 THR H CB 1 ATOM 4949 O OG1 . THR C 3 28 ? 63.137 38.092 119.859 1.00 31.82 ? 28 THR H OG1 1 ATOM 4950 C CG2 . THR C 3 28 ? 64.356 40.233 120.260 1.00 29.68 ? 28 THR H CG2 1 ATOM 4951 N N . PHE C 3 29 ? 64.968 38.988 115.812 1.00 29.55 ? 29 PHE H N 1 ATOM 4952 C CA . PHE C 3 29 ? 65.299 38.213 114.614 1.00 30.63 ? 29 PHE H CA 1 ATOM 4953 C C . PHE C 3 29 ? 65.835 36.801 114.862 1.00 32.00 ? 29 PHE H C 1 ATOM 4954 O O . PHE C 3 29 ? 65.264 35.782 114.498 1.00 33.64 ? 29 PHE H O 1 ATOM 4955 C CB . PHE C 3 29 ? 66.288 39.032 113.799 1.00 28.43 ? 29 PHE H CB 1 ATOM 4956 C CG . PHE C 3 29 ? 66.363 38.696 112.310 1.00 26.35 ? 29 PHE H CG 1 ATOM 4957 C CD1 . PHE C 3 29 ? 65.224 38.725 111.535 1.00 25.77 ? 29 PHE H CD1 1 ATOM 4958 C CD2 . PHE C 3 29 ? 67.579 38.425 111.717 1.00 26.83 ? 29 PHE H CD2 1 ATOM 4959 C CE1 . PHE C 3 29 ? 65.286 38.491 110.178 1.00 25.45 ? 29 PHE H CE1 1 ATOM 4960 C CE2 . PHE C 3 29 ? 67.634 38.199 110.359 1.00 26.69 ? 29 PHE H CE2 1 ATOM 4961 C CZ . PHE C 3 29 ? 66.492 38.231 109.584 1.00 26.25 ? 29 PHE H CZ 1 ATOM 4962 N N . THR C 3 30 ? 66.916 36.782 115.584 1.00 33.35 ? 30 THR H N 1 ATOM 4963 C CA . THR C 3 30 ? 67.585 35.613 116.086 1.00 34.37 ? 30 THR H CA 1 ATOM 4964 C C . THR C 3 30 ? 66.680 34.528 116.706 1.00 34.57 ? 30 THR H C 1 ATOM 4965 O O . THR C 3 30 ? 67.108 33.366 116.706 1.00 34.60 ? 30 THR H O 1 ATOM 4966 C CB . THR C 3 30 ? 68.607 36.181 117.072 1.00 35.66 ? 30 THR H CB 1 ATOM 4967 O OG1 . THR C 3 30 ? 69.206 37.296 116.428 1.00 36.00 ? 30 THR H OG1 1 ATOM 4968 C CG2 . THR C 3 30 ? 69.682 35.196 117.479 1.00 37.84 ? 30 THR H CG2 1 ATOM 4969 N N . ASN C 3 31 ? 65.504 34.794 117.309 1.00 33.45 ? 31 ASN H N 1 ATOM 4970 C CA . ASN C 3 31 ? 64.782 33.680 117.914 1.00 31.70 ? 31 ASN H CA 1 ATOM 4971 C C . ASN C 3 31 ? 63.646 33.071 117.079 1.00 28.05 ? 31 ASN H C 1 ATOM 4972 O O . ASN C 3 31 ? 62.894 32.176 117.487 1.00 28.34 ? 31 ASN H O 1 ATOM 4973 C CB . ASN C 3 31 ? 64.249 34.113 119.267 1.00 37.66 ? 31 ASN H CB 1 ATOM 4974 C CG . ASN C 3 31 ? 63.916 32.857 120.086 1.00 41.92 ? 31 ASN H CG 1 ATOM 4975 O OD1 . ASN C 3 31 ? 64.668 31.871 120.141 1.00 43.53 ? 31 ASN H OD1 1 ATOM 4976 N ND2 . ASN C 3 31 ? 62.753 32.767 120.726 1.00 43.07 ? 31 ASN H ND2 1 ATOM 4977 N N . TYR C 3 32 ? 63.485 33.516 115.838 1.00 22.11 ? 32 TYR H N 1 ATOM 4978 C CA . TYR C 3 32 ? 62.483 32.992 114.945 1.00 15.73 ? 32 TYR H CA 1 ATOM 4979 C C . TYR C 3 32 ? 63.226 32.780 113.649 1.00 14.63 ? 32 TYR H C 1 ATOM 4980 O O . TYR C 3 32 ? 64.037 33.632 113.320 1.00 14.75 ? 32 TYR H O 1 ATOM 4981 C CB . TYR C 3 32 ? 61.328 34.012 114.799 1.00 14.80 ? 32 TYR H CB 1 ATOM 4982 C CG . TYR C 3 32 ? 60.425 33.874 116.004 1.00 13.87 ? 32 TYR H CG 1 ATOM 4983 C CD1 . TYR C 3 32 ? 59.447 32.910 116.017 1.00 13.35 ? 32 TYR H CD1 1 ATOM 4984 C CD2 . TYR C 3 32 ? 60.663 34.646 117.115 1.00 11.99 ? 32 TYR H CD2 1 ATOM 4985 C CE1 . TYR C 3 32 ? 58.713 32.702 117.153 1.00 12.91 ? 32 TYR H CE1 1 ATOM 4986 C CE2 . TYR C 3 32 ? 59.924 34.428 118.248 1.00 13.17 ? 32 TYR H CE2 1 ATOM 4987 C CZ . TYR C 3 32 ? 58.966 33.449 118.254 1.00 13.04 ? 32 TYR H CZ 1 ATOM 4988 O OH . TYR C 3 32 ? 58.328 33.188 119.432 1.00 16.48 ? 32 TYR H OH 1 ATOM 4989 N N . GLY C 3 33 ? 62.981 31.733 112.866 1.00 14.07 ? 33 GLY H N 1 ATOM 4990 C CA . GLY C 3 33 ? 63.760 31.550 111.631 1.00 15.23 ? 33 GLY H CA 1 ATOM 4991 C C . GLY C 3 33 ? 63.036 32.006 110.359 1.00 14.25 ? 33 GLY H C 1 ATOM 4992 O O . GLY C 3 33 ? 61.818 32.141 110.423 1.00 16.58 ? 33 GLY H O 1 ATOM 4993 N N . MET C 3 34 ? 63.640 32.270 109.185 1.00 13.68 ? 34 MET H N 1 ATOM 4994 C CA . MET C 3 34 ? 62.907 32.617 107.953 1.00 12.54 ? 34 MET H CA 1 ATOM 4995 C C . MET C 3 34 ? 62.550 31.470 107.040 1.00 13.76 ? 34 MET H C 1 ATOM 4996 O O . MET C 3 34 ? 63.401 30.663 106.658 1.00 14.24 ? 34 MET H O 1 ATOM 4997 C CB . MET C 3 34 ? 63.648 33.524 107.087 1.00 9.26 ? 34 MET H CB 1 ATOM 4998 C CG . MET C 3 34 ? 63.380 34.887 107.637 1.00 11.05 ? 34 MET H CG 1 ATOM 4999 S SD . MET C 3 34 ? 61.639 35.371 107.560 1.00 12.06 ? 34 MET H SD 1 ATOM 5000 C CE . MET C 3 34 ? 62.004 36.959 108.232 1.00 10.41 ? 34 MET H CE 1 ATOM 5001 N N . ASN C 3 35 ? 61.280 31.456 106.663 1.00 12.84 ? 35 ASN H N 1 ATOM 5002 C CA . ASN C 3 35 ? 60.611 30.475 105.807 1.00 10.92 ? 35 ASN H CA 1 ATOM 5003 C C . ASN C 3 35 ? 60.476 31.176 104.480 1.00 10.23 ? 35 ASN H C 1 ATOM 5004 O O . ASN C 3 35 ? 60.055 32.341 104.487 1.00 11.15 ? 35 ASN H O 1 ATOM 5005 C CB . ASN C 3 35 ? 59.215 30.207 106.285 1.00 12.72 ? 35 ASN H CB 1 ATOM 5006 C CG . ASN C 3 35 ? 58.927 28.758 106.515 1.00 16.37 ? 35 ASN H CG 1 ATOM 5007 O OD1 . ASN C 3 35 ? 59.843 27.977 106.760 1.00 18.18 ? 35 ASN H OD1 1 ATOM 5008 N ND2 . ASN C 3 35 ? 57.669 28.351 106.426 1.00 16.73 ? 35 ASN H ND2 1 ATOM 5009 N N . TRP C 3 36 ? 60.861 30.604 103.348 1.00 6.88 ? 36 TRP H N 1 ATOM 5010 C CA . TRP C 3 36 ? 60.647 31.228 102.041 1.00 7.67 ? 36 TRP H CA 1 ATOM 5011 C C . TRP C 3 36 ? 59.723 30.341 101.206 1.00 8.86 ? 36 TRP H C 1 ATOM 5012 O O . TRP C 3 36 ? 59.826 29.103 101.204 1.00 9.85 ? 36 TRP H O 1 ATOM 5013 C CB . TRP C 3 36 ? 61.923 31.376 101.316 1.00 7.57 ? 36 TRP H CB 1 ATOM 5014 C CG . TRP C 3 36 ? 62.842 32.489 101.801 1.00 7.83 ? 36 TRP H CG 1 ATOM 5015 C CD1 . TRP C 3 36 ? 63.920 32.279 102.653 1.00 9.47 ? 36 TRP H CD1 1 ATOM 5016 C CD2 . TRP C 3 36 ? 62.719 33.790 101.372 1.00 8.65 ? 36 TRP H CD2 1 ATOM 5017 N NE1 . TRP C 3 36 ? 64.488 33.465 102.747 1.00 10.87 ? 36 TRP H NE1 1 ATOM 5018 C CE2 . TRP C 3 36 ? 63.807 34.392 102.009 1.00 10.92 ? 36 TRP H CE2 1 ATOM 5019 C CE3 . TRP C 3 36 ? 61.852 34.487 100.559 1.00 8.16 ? 36 TRP H CE3 1 ATOM 5020 C CZ2 . TRP C 3 36 ? 64.029 35.748 101.804 1.00 11.62 ? 36 TRP H CZ2 1 ATOM 5021 C CZ3 . TRP C 3 36 ? 62.087 35.833 100.380 1.00 10.77 ? 36 TRP H CZ3 1 ATOM 5022 C CH2 . TRP C 3 36 ? 63.161 36.467 100.993 1.00 12.63 ? 36 TRP H CH2 1 ATOM 5023 N N . VAL C 3 37 ? 58.775 30.916 100.485 1.00 10.76 ? 37 VAL H N 1 ATOM 5024 C CA . VAL C 3 37 ? 57.725 30.185 99.782 1.00 10.14 ? 37 VAL H CA 1 ATOM 5025 C C . VAL C 3 37 ? 57.524 30.810 98.389 1.00 13.87 ? 37 VAL H C 1 ATOM 5026 O O . VAL C 3 37 ? 57.669 32.034 98.200 1.00 11.60 ? 37 VAL H O 1 ATOM 5027 C CB . VAL C 3 37 ? 56.470 30.264 100.715 1.00 8.13 ? 37 VAL H CB 1 ATOM 5028 C CG1 . VAL C 3 37 ? 55.189 30.523 99.945 1.00 6.79 ? 37 VAL H CG1 1 ATOM 5029 C CG2 . VAL C 3 37 ? 56.327 28.964 101.432 1.00 6.44 ? 37 VAL H CG2 1 ATOM 5030 N N . LYS C 3 38 ? 57.208 29.922 97.434 1.00 17.98 ? 38 LYS H N 1 ATOM 5031 C CA . LYS C 3 38 ? 56.949 30.251 96.039 1.00 23.15 ? 38 LYS H CA 1 ATOM 5032 C C . LYS C 3 38 ? 55.486 30.098 95.741 1.00 22.80 ? 38 LYS H C 1 ATOM 5033 O O . LYS C 3 38 ? 54.968 29.007 95.935 1.00 23.93 ? 38 LYS H O 1 ATOM 5034 C CB . LYS C 3 38 ? 57.714 29.308 95.142 1.00 25.94 ? 38 LYS H CB 1 ATOM 5035 C CG . LYS C 3 38 ? 57.695 29.609 93.658 1.00 30.08 ? 38 LYS H CG 1 ATOM 5036 C CD . LYS C 3 38 ? 58.247 28.343 93.022 1.00 34.01 ? 38 LYS H CD 1 ATOM 5037 C CE . LYS C 3 38 ? 58.852 28.542 91.645 1.00 36.59 ? 38 LYS H CE 1 ATOM 5038 N NZ . LYS C 3 38 ? 59.379 27.261 91.215 1.00 38.37 ? 38 LYS H NZ 1 ATOM 5039 N N . GLN C 3 39 ? 54.783 31.129 95.297 1.00 24.57 ? 39 GLN H N 1 ATOM 5040 C CA . GLN C 3 39 ? 53.394 30.998 94.892 1.00 27.10 ? 39 GLN H CA 1 ATOM 5041 C C . GLN C 3 39 ? 53.513 31.343 93.446 1.00 27.85 ? 39 GLN H C 1 ATOM 5042 O O . GLN C 3 39 ? 53.773 32.483 93.033 1.00 28.86 ? 39 GLN H O 1 ATOM 5043 C CB . GLN C 3 39 ? 52.439 31.999 95.495 1.00 29.44 ? 39 GLN H CB 1 ATOM 5044 C CG . GLN C 3 39 ? 51.072 31.529 95.032 1.00 32.99 ? 39 GLN H CG 1 ATOM 5045 C CD . GLN C 3 39 ? 49.895 31.909 95.909 1.00 34.51 ? 39 GLN H CD 1 ATOM 5046 O OE1 . GLN C 3 39 ? 49.065 31.100 96.310 1.00 35.06 ? 39 GLN H OE1 1 ATOM 5047 N NE2 . GLN C 3 39 ? 49.777 33.169 96.247 1.00 38.68 ? 39 GLN H NE2 1 ATOM 5048 N N . ALA C 3 40 ? 53.506 30.269 92.701 1.00 29.74 ? 40 ALA H N 1 ATOM 5049 C CA . ALA C 3 40 ? 53.619 30.381 91.257 1.00 31.95 ? 40 ALA H CA 1 ATOM 5050 C C . ALA C 3 40 ? 52.178 30.453 90.822 1.00 33.79 ? 40 ALA H C 1 ATOM 5051 O O . ALA C 3 40 ? 51.360 29.727 91.407 1.00 33.98 ? 40 ALA H O 1 ATOM 5052 C CB . ALA C 3 40 ? 54.242 29.141 90.651 1.00 31.85 ? 40 ALA H CB 1 ATOM 5053 N N . PRO C 3 41 ? 51.798 31.284 89.847 1.00 34.08 ? 41 PRO H N 1 ATOM 5054 C CA . PRO C 3 41 ? 50.380 31.467 89.460 1.00 33.23 ? 41 PRO H CA 1 ATOM 5055 C C . PRO C 3 41 ? 49.532 30.183 89.276 1.00 33.54 ? 41 PRO H C 1 ATOM 5056 O O . PRO C 3 41 ? 48.815 29.740 90.191 1.00 35.43 ? 41 PRO H O 1 ATOM 5057 C CB . PRO C 3 41 ? 50.525 32.318 88.219 1.00 34.23 ? 41 PRO H CB 1 ATOM 5058 C CG . PRO C 3 41 ? 51.784 33.136 88.511 1.00 35.74 ? 41 PRO H CG 1 ATOM 5059 C CD . PRO C 3 41 ? 52.730 32.131 89.111 1.00 35.21 ? 41 PRO H CD 1 ATOM 5060 N N . GLY C 3 42 ? 49.580 29.519 88.125 1.00 32.25 ? 42 GLY H N 1 ATOM 5061 C CA . GLY C 3 42 ? 48.817 28.302 87.931 1.00 30.40 ? 42 GLY H CA 1 ATOM 5062 C C . GLY C 3 42 ? 49.512 27.105 88.558 1.00 29.33 ? 42 GLY H C 1 ATOM 5063 O O . GLY C 3 42 ? 50.072 26.294 87.823 1.00 29.14 ? 42 GLY H O 1 ATOM 5064 N N . LYS C 3 43 ? 49.547 27.025 89.891 1.00 28.42 ? 43 LYS H N 1 ATOM 5065 C CA . LYS C 3 43 ? 50.098 25.898 90.624 1.00 27.69 ? 43 LYS H CA 1 ATOM 5066 C C . LYS C 3 43 ? 49.776 26.074 92.104 1.00 27.36 ? 43 LYS H C 1 ATOM 5067 O O . LYS C 3 43 ? 49.075 25.222 92.646 1.00 27.53 ? 43 LYS H O 1 ATOM 5068 C CB . LYS C 3 43 ? 51.625 25.785 90.436 1.00 27.28 ? 43 LYS H CB 1 ATOM 5069 C CG . LYS C 3 43 ? 52.140 24.341 90.566 1.00 26.87 ? 43 LYS H CG 1 ATOM 5070 C CD . LYS C 3 43 ? 51.445 23.373 89.598 1.00 26.57 ? 43 LYS H CD 1 ATOM 5071 C CE . LYS C 3 43 ? 52.011 21.958 89.707 1.00 26.36 ? 43 LYS H CE 1 ATOM 5072 N NZ . LYS C 3 43 ? 51.154 20.999 89.031 1.00 26.25 ? 43 LYS H NZ 1 ATOM 5073 N N . GLY C 3 44 ? 50.223 27.111 92.821 1.00 27.52 ? 44 GLY H N 1 ATOM 5074 C CA . GLY C 3 44 ? 49.868 27.256 94.238 1.00 25.13 ? 44 GLY H CA 1 ATOM 5075 C C . GLY C 3 44 ? 51.060 27.618 95.136 1.00 24.16 ? 44 GLY H C 1 ATOM 5076 O O . GLY C 3 44 ? 52.052 28.177 94.631 1.00 25.95 ? 44 GLY H O 1 ATOM 5077 N N . LEU C 3 45 ? 51.009 27.310 96.450 1.00 21.16 ? 45 LEU H N 1 ATOM 5078 C CA . LEU C 3 45 ? 52.060 27.637 97.404 1.00 18.19 ? 45 LEU H CA 1 ATOM 5079 C C . LEU C 3 45 ? 53.111 26.515 97.643 1.00 20.88 ? 45 LEU H C 1 ATOM 5080 O O . LEU C 3 45 ? 52.721 25.381 97.970 1.00 19.38 ? 45 LEU H O 1 ATOM 5081 C CB . LEU C 3 45 ? 51.389 27.985 98.692 1.00 13.50 ? 45 LEU H CB 1 ATOM 5082 C CG . LEU C 3 45 ? 50.585 29.230 98.946 1.00 9.41 ? 45 LEU H CG 1 ATOM 5083 C CD1 . LEU C 3 45 ? 49.832 29.055 100.263 1.00 7.13 ? 45 LEU H CD1 1 ATOM 5084 C CD2 . LEU C 3 45 ? 51.470 30.420 99.086 1.00 10.33 ? 45 LEU H CD2 1 ATOM 5085 N N . GLU C 3 46 ? 54.440 26.732 97.511 1.00 22.15 ? 46 GLU H N 1 ATOM 5086 C CA . GLU C 3 46 ? 55.483 25.734 97.742 1.00 22.75 ? 46 GLU H CA 1 ATOM 5087 C C . GLU C 3 46 ? 56.500 26.080 98.835 1.00 22.81 ? 46 GLU H C 1 ATOM 5088 O O . GLU C 3 46 ? 57.121 27.138 98.687 1.00 25.72 ? 46 GLU H O 1 ATOM 5089 C CB . GLU C 3 46 ? 56.238 25.534 96.472 1.00 26.12 ? 46 GLU H CB 1 ATOM 5090 C CG . GLU C 3 46 ? 56.223 24.069 96.131 1.00 30.49 ? 46 GLU H CG 1 ATOM 5091 C CD . GLU C 3 46 ? 56.909 23.660 94.816 1.00 33.51 ? 46 GLU H CD 1 ATOM 5092 O OE1 . GLU C 3 46 ? 57.270 24.532 94.004 1.00 36.64 ? 46 GLU H OE1 1 ATOM 5093 O OE2 . GLU C 3 46 ? 57.066 22.446 94.593 1.00 35.72 ? 46 GLU H OE2 1 ATOM 5094 N N . TRP C 3 47 ? 56.741 25.322 99.930 1.00 21.77 ? 47 TRP H N 1 ATOM 5095 C CA . TRP C 3 47 ? 57.830 25.638 100.858 1.00 20.94 ? 47 TRP H CA 1 ATOM 5096 C C . TRP C 3 47 ? 59.203 25.572 100.147 1.00 20.65 ? 47 TRP H C 1 ATOM 5097 O O . TRP C 3 47 ? 59.489 24.631 99.390 1.00 20.11 ? 47 TRP H O 1 ATOM 5098 C CB . TRP C 3 47 ? 57.817 24.663 102.030 1.00 18.75 ? 47 TRP H CB 1 ATOM 5099 C CG . TRP C 3 47 ? 58.897 24.915 103.107 1.00 20.13 ? 47 TRP H CG 1 ATOM 5100 C CD1 . TRP C 3 47 ? 58.943 26.061 103.869 1.00 19.97 ? 47 TRP H CD1 1 ATOM 5101 C CD2 . TRP C 3 47 ? 59.842 24.006 103.521 1.00 20.31 ? 47 TRP H CD2 1 ATOM 5102 N NE1 . TRP C 3 47 ? 59.867 25.865 104.763 1.00 18.96 ? 47 TRP H NE1 1 ATOM 5103 C CE2 . TRP C 3 47 ? 60.417 24.658 104.591 1.00 20.28 ? 47 TRP H CE2 1 ATOM 5104 C CE3 . TRP C 3 47 ? 60.268 22.738 103.174 1.00 18.40 ? 47 TRP H CE3 1 ATOM 5105 C CZ2 . TRP C 3 47 ? 61.422 24.048 105.332 1.00 20.52 ? 47 TRP H CZ2 1 ATOM 5106 C CZ3 . TRP C 3 47 ? 61.266 22.137 103.920 1.00 19.51 ? 47 TRP H CZ3 1 ATOM 5107 C CH2 . TRP C 3 47 ? 61.843 22.783 104.995 1.00 19.98 ? 47 TRP H CH2 1 ATOM 5108 N N . MET C 3 48 ? 60.092 26.547 100.299 1.00 18.87 ? 48 MET H N 1 ATOM 5109 C CA . MET C 3 48 ? 61.392 26.468 99.639 1.00 17.72 ? 48 MET H CA 1 ATOM 5110 C C . MET C 3 48 ? 62.514 25.941 100.534 1.00 17.73 ? 48 MET H C 1 ATOM 5111 O O . MET C 3 48 ? 63.474 25.297 100.116 1.00 19.63 ? 48 MET H O 1 ATOM 5112 C CB . MET C 3 48 ? 61.739 27.837 99.128 1.00 16.60 ? 48 MET H CB 1 ATOM 5113 C CG . MET C 3 48 ? 60.933 28.025 97.897 1.00 15.32 ? 48 MET H CG 1 ATOM 5114 S SD . MET C 3 48 ? 61.008 29.746 97.421 1.00 18.73 ? 48 MET H SD 1 ATOM 5115 C CE . MET C 3 48 ? 62.668 29.769 96.829 1.00 19.15 ? 48 MET H CE 1 ATOM 5116 N N . GLY C 3 49 ? 62.427 26.287 101.801 1.00 17.04 ? 49 GLY H N 1 ATOM 5117 C CA . GLY C 3 49 ? 63.365 25.888 102.818 1.00 14.84 ? 49 GLY H CA 1 ATOM 5118 C C . GLY C 3 49 ? 63.218 26.926 103.925 1.00 14.55 ? 49 GLY H C 1 ATOM 5119 O O . GLY C 3 49 ? 62.363 27.820 103.836 1.00 15.31 ? 49 GLY H O 1 ATOM 5120 N N . TRP C 3 50 ? 64.121 26.868 104.897 1.00 12.61 ? 50 TRP H N 1 ATOM 5121 C CA . TRP C 3 50 ? 64.011 27.701 106.078 1.00 9.44 ? 50 TRP H CA 1 ATOM 5122 C C . TRP C 3 50 ? 65.424 28.063 106.525 1.00 10.11 ? 50 TRP H C 1 ATOM 5123 O O . TRP C 3 50 ? 66.322 27.238 106.256 1.00 9.08 ? 50 TRP H O 1 ATOM 5124 C CB . TRP C 3 50 ? 63.256 26.874 107.092 1.00 7.11 ? 50 TRP H CB 1 ATOM 5125 C CG . TRP C 3 50 ? 63.356 27.381 108.529 1.00 8.98 ? 50 TRP H CG 1 ATOM 5126 C CD1 . TRP C 3 50 ? 62.485 28.305 109.057 1.00 7.40 ? 50 TRP H CD1 1 ATOM 5127 C CD2 . TRP C 3 50 ? 64.258 26.913 109.464 1.00 7.82 ? 50 TRP H CD2 1 ATOM 5128 N NE1 . TRP C 3 50 ? 62.827 28.397 110.326 1.00 5.84 ? 50 TRP H NE1 1 ATOM 5129 C CE2 . TRP C 3 50 ? 63.868 27.591 110.609 1.00 5.52 ? 50 TRP H CE2 1 ATOM 5130 C CE3 . TRP C 3 50 ? 65.307 26.018 109.475 1.00 5.21 ? 50 TRP H CE3 1 ATOM 5131 C CZ2 . TRP C 3 50 ? 64.504 27.402 111.802 1.00 3.93 ? 50 TRP H CZ2 1 ATOM 5132 C CZ3 . TRP C 3 50 ? 65.938 25.837 110.679 1.00 2.82 ? 50 TRP H CZ3 1 ATOM 5133 C CH2 . TRP C 3 50 ? 65.541 26.511 111.816 1.00 3.29 ? 50 TRP H CH2 1 ATOM 5134 N N . ILE C 3 51 ? 65.679 29.234 107.137 1.00 8.88 ? 51 ILE H N 1 ATOM 5135 C CA . ILE C 3 51 ? 66.998 29.520 107.662 1.00 8.36 ? 51 ILE H CA 1 ATOM 5136 C C . ILE C 3 51 ? 66.854 29.867 109.154 1.00 9.15 ? 51 ILE H C 1 ATOM 5137 O O . ILE C 3 51 ? 65.878 30.440 109.639 1.00 7.18 ? 51 ILE H O 1 ATOM 5138 C CB . ILE C 3 51 ? 67.666 30.677 106.852 1.00 8.55 ? 51 ILE H CB 1 ATOM 5139 C CG1 . ILE C 3 51 ? 69.140 30.745 107.186 1.00 8.09 ? 51 ILE H CG1 1 ATOM 5140 C CG2 . ILE C 3 51 ? 67.082 32.044 107.204 1.00 11.55 ? 51 ILE H CG2 1 ATOM 5141 C CD1 . ILE C 3 51 ? 69.887 31.645 106.223 1.00 8.29 ? 51 ILE H CD1 1 ATOM 5142 N N . ASN C 3 52 ? 67.863 29.432 109.896 1.00 11.78 ? 52 ASN H N 1 ATOM 5143 C CA . ASN C 3 52 ? 67.988 29.600 111.311 1.00 9.02 ? 52 ASN H CA 1 ATOM 5144 C C . ASN C 3 52 ? 68.653 30.967 111.558 1.00 11.62 ? 52 ASN H C 1 ATOM 5145 O O . ASN C 3 52 ? 69.871 31.084 111.514 1.00 11.95 ? 52 ASN H O 1 ATOM 5146 C CB . ASN C 3 52 ? 68.831 28.413 111.733 1.00 11.61 ? 52 ASN H CB 1 ATOM 5147 C CG . ASN C 3 52 ? 68.983 28.238 113.237 1.00 13.58 ? 52 ASN H CG 1 ATOM 5148 O OD1 . ASN C 3 52 ? 69.128 29.196 114.015 1.00 11.33 ? 52 ASN H OD1 1 ATOM 5149 N ND2 . ASN C 3 52 ? 68.935 26.971 113.658 1.00 14.35 ? 52 ASN H ND2 1 ATOM 5150 N N . THR C 3 53 A 67.967 32.053 111.853 1.00 11.79 ? 52 THR H N 1 ATOM 5151 C CA . THR C 3 53 A 68.584 33.352 112.079 1.00 12.39 ? 52 THR H CA 1 ATOM 5152 C C . THR C 3 53 A 69.527 33.410 113.303 1.00 14.85 ? 52 THR H C 1 ATOM 5153 O O . THR C 3 53 A 70.196 34.413 113.631 1.00 16.51 ? 52 THR H O 1 ATOM 5154 C CB . THR C 3 53 A 67.400 34.341 112.142 1.00 13.54 ? 52 THR H CB 1 ATOM 5155 O OG1 . THR C 3 53 A 66.546 33.799 113.096 1.00 11.48 ? 52 THR H OG1 1 ATOM 5156 C CG2 . THR C 3 53 A 66.543 34.436 110.892 1.00 14.17 ? 52 THR H CG2 1 ATOM 5157 N N . ASN C 3 54 ? 69.594 32.287 114.019 1.00 17.80 ? 53 ASN H N 1 ATOM 5158 C CA . ASN C 3 54 ? 70.544 32.188 115.093 1.00 19.48 ? 53 ASN H CA 1 ATOM 5159 C C . ASN C 3 54 ? 71.799 31.499 114.598 1.00 18.33 ? 53 ASN H C 1 ATOM 5160 O O . ASN C 3 54 ? 72.873 32.018 114.843 1.00 19.16 ? 53 ASN H O 1 ATOM 5161 C CB . ASN C 3 54 ? 69.937 31.425 116.211 1.00 21.48 ? 53 ASN H CB 1 ATOM 5162 C CG . ASN C 3 54 ? 70.870 31.385 117.396 1.00 23.82 ? 53 ASN H CG 1 ATOM 5163 O OD1 . ASN C 3 54 ? 71.736 30.510 117.478 1.00 27.56 ? 53 ASN H OD1 1 ATOM 5164 N ND2 . ASN C 3 54 ? 70.682 32.283 118.365 1.00 24.18 ? 53 ASN H ND2 1 ATOM 5165 N N . THR C 3 55 ? 71.811 30.394 113.876 1.00 17.75 ? 54 THR H N 1 ATOM 5166 C CA . THR C 3 55 ? 73.094 29.856 113.458 1.00 18.93 ? 54 THR H CA 1 ATOM 5167 C C . THR C 3 55 ? 73.587 30.344 112.091 1.00 20.21 ? 54 THR H C 1 ATOM 5168 O O . THR C 3 55 ? 74.780 30.376 111.769 1.00 20.70 ? 54 THR H O 1 ATOM 5169 C CB . THR C 3 55 ? 73.022 28.319 113.453 1.00 17.26 ? 54 THR H CB 1 ATOM 5170 O OG1 . THR C 3 55 ? 72.072 27.791 112.526 1.00 12.79 ? 54 THR H OG1 1 ATOM 5171 C CG2 . THR C 3 55 ? 72.710 27.922 114.837 1.00 13.27 ? 54 THR H CG2 1 ATOM 5172 N N . GLY C 3 56 ? 72.587 30.672 111.269 1.00 21.55 ? 55 GLY H N 1 ATOM 5173 C CA . GLY C 3 56 ? 72.712 31.013 109.858 1.00 20.90 ? 55 GLY H CA 1 ATOM 5174 C C . GLY C 3 56 ? 72.437 29.805 108.953 1.00 22.50 ? 55 GLY H C 1 ATOM 5175 O O . GLY C 3 56 ? 72.496 29.961 107.731 1.00 21.06 ? 55 GLY H O 1 ATOM 5176 N N . GLU C 3 57 ? 72.091 28.593 109.438 1.00 24.35 ? 56 GLU H N 1 ATOM 5177 C CA . GLU C 3 57 ? 72.009 27.433 108.554 1.00 24.44 ? 56 GLU H CA 1 ATOM 5178 C C . GLU C 3 57 ? 70.724 27.161 107.845 1.00 20.23 ? 56 GLU H C 1 ATOM 5179 O O . GLU C 3 57 ? 69.699 27.013 108.507 1.00 19.34 ? 56 GLU H O 1 ATOM 5180 C CB . GLU C 3 57 ? 72.368 26.178 109.281 1.00 26.68 ? 56 GLU H CB 1 ATOM 5181 C CG . GLU C 3 57 ? 73.662 25.724 108.614 1.00 31.89 ? 56 GLU H CG 1 ATOM 5182 C CD . GLU C 3 57 ? 73.856 24.213 108.616 1.00 34.35 ? 56 GLU H CD 1 ATOM 5183 O OE1 . GLU C 3 57 ? 73.534 23.573 109.627 1.00 35.42 ? 56 GLU H OE1 1 ATOM 5184 O OE2 . GLU C 3 57 ? 74.317 23.670 107.601 1.00 34.46 ? 56 GLU H OE2 1 ATOM 5185 N N . PRO C 3 58 ? 70.751 27.167 106.514 1.00 18.72 ? 57 PRO H N 1 ATOM 5186 C CA . PRO C 3 58 ? 69.650 26.824 105.662 1.00 17.65 ? 57 PRO H CA 1 ATOM 5187 C C . PRO C 3 58 ? 69.530 25.378 105.341 1.00 16.73 ? 57 PRO H C 1 ATOM 5188 O O . PRO C 3 58 ? 70.489 24.616 105.152 1.00 17.43 ? 57 PRO H O 1 ATOM 5189 C CB . PRO C 3 58 ? 69.833 27.642 104.402 1.00 18.02 ? 57 PRO H CB 1 ATOM 5190 C CG . PRO C 3 58 ? 71.323 27.595 104.224 1.00 18.43 ? 57 PRO H CG 1 ATOM 5191 C CD . PRO C 3 58 ? 71.772 27.795 105.673 1.00 20.17 ? 57 PRO H CD 1 ATOM 5192 N N . THR C 3 59 ? 68.233 25.172 105.308 1.00 15.22 ? 58 THR H N 1 ATOM 5193 C CA . THR C 3 59 ? 67.650 23.959 104.809 1.00 16.16 ? 58 THR H CA 1 ATOM 5194 C C . THR C 3 59 ? 67.067 24.397 103.465 1.00 17.45 ? 58 THR H C 1 ATOM 5195 O O . THR C 3 59 ? 66.702 25.570 103.265 1.00 20.23 ? 58 THR H O 1 ATOM 5196 C CB . THR C 3 59 ? 66.588 23.514 105.767 1.00 15.95 ? 58 THR H CB 1 ATOM 5197 O OG1 . THR C 3 59 ? 67.249 23.532 107.012 1.00 17.53 ? 58 THR H OG1 1 ATOM 5198 C CG2 . THR C 3 59 ? 66.041 22.116 105.544 1.00 15.62 ? 58 THR H CG2 1 ATOM 5199 N N . TYR C 3 60 ? 67.025 23.491 102.506 1.00 17.52 ? 59 TYR H N 1 ATOM 5200 C CA . TYR C 3 60 ? 66.442 23.773 101.225 1.00 15.80 ? 59 TYR H CA 1 ATOM 5201 C C . TYR C 3 60 ? 65.543 22.595 100.956 1.00 16.38 ? 59 TYR H C 1 ATOM 5202 O O . TYR C 3 60 ? 65.635 21.537 101.591 1.00 15.71 ? 59 TYR H O 1 ATOM 5203 C CB . TYR C 3 60 ? 67.478 23.852 100.156 1.00 15.05 ? 59 TYR H CB 1 ATOM 5204 C CG . TYR C 3 60 ? 68.314 25.112 100.272 1.00 13.63 ? 59 TYR H CG 1 ATOM 5205 C CD1 . TYR C 3 60 ? 67.907 26.325 99.759 1.00 13.14 ? 59 TYR H CD1 1 ATOM 5206 C CD2 . TYR C 3 60 ? 69.524 25.024 100.876 1.00 12.97 ? 59 TYR H CD2 1 ATOM 5207 C CE1 . TYR C 3 60 ? 68.719 27.431 99.844 1.00 12.11 ? 59 TYR H CE1 1 ATOM 5208 C CE2 . TYR C 3 60 ? 70.343 26.121 100.974 1.00 13.36 ? 59 TYR H CE2 1 ATOM 5209 C CZ . TYR C 3 60 ? 69.944 27.317 100.458 1.00 12.60 ? 59 TYR H CZ 1 ATOM 5210 O OH . TYR C 3 60 ? 70.842 28.369 100.588 1.00 13.18 ? 59 TYR H OH 1 ATOM 5211 N N . GLY C 3 61 ? 64.593 22.835 100.085 1.00 20.08 ? 60 GLY H N 1 ATOM 5212 C CA . GLY C 3 61 ? 63.679 21.811 99.644 1.00 22.23 ? 60 GLY H CA 1 ATOM 5213 C C . GLY C 3 61 ? 64.309 21.250 98.402 1.00 24.70 ? 60 GLY H C 1 ATOM 5214 O O . GLY C 3 61 ? 65.119 21.907 97.764 1.00 25.19 ? 60 GLY H O 1 ATOM 5215 N N . GLU C 3 62 ? 63.875 20.078 97.990 1.00 25.50 ? 61 GLU H N 1 ATOM 5216 C CA . GLU C 3 62 ? 64.452 19.375 96.862 1.00 28.65 ? 61 GLU H CA 1 ATOM 5217 C C . GLU C 3 62 ? 64.428 20.234 95.625 1.00 27.47 ? 61 GLU H C 1 ATOM 5218 O O . GLU C 3 62 ? 65.467 20.698 95.192 1.00 26.63 ? 61 GLU H O 1 ATOM 5219 C CB . GLU C 3 62 ? 63.682 18.080 96.630 1.00 32.66 ? 61 GLU H CB 1 ATOM 5220 C CG . GLU C 3 62 ? 64.564 16.848 96.473 1.00 38.94 ? 61 GLU H CG 1 ATOM 5221 C CD . GLU C 3 62 ? 65.362 16.472 97.729 1.00 42.56 ? 61 GLU H CD 1 ATOM 5222 O OE1 . GLU C 3 62 ? 66.300 17.204 98.090 1.00 43.78 ? 61 GLU H OE1 1 ATOM 5223 O OE2 . GLU C 3 62 ? 65.050 15.434 98.340 1.00 45.06 ? 61 GLU H OE2 1 ATOM 5224 N N . GLU C 3 63 ? 63.273 20.575 95.103 1.00 26.94 ? 62 GLU H N 1 ATOM 5225 C CA . GLU C 3 63 ? 63.143 21.499 93.999 1.00 27.77 ? 62 GLU H CA 1 ATOM 5226 C C . GLU C 3 63 ? 63.918 22.830 94.095 1.00 27.28 ? 62 GLU H C 1 ATOM 5227 O O . GLU C 3 63 ? 63.896 23.655 93.171 1.00 28.62 ? 62 GLU H O 1 ATOM 5228 C CB . GLU C 3 63 ? 61.676 21.707 93.891 1.00 31.28 ? 62 GLU H CB 1 ATOM 5229 C CG . GLU C 3 63 ? 61.322 22.338 92.579 1.00 33.79 ? 62 GLU H CG 1 ATOM 5230 C CD . GLU C 3 63 ? 59.828 22.433 92.342 1.00 36.73 ? 62 GLU H CD 1 ATOM 5231 O OE1 . GLU C 3 63 ? 59.136 21.423 92.587 1.00 38.01 ? 62 GLU H OE1 1 ATOM 5232 O OE2 . GLU C 3 63 ? 59.392 23.511 91.888 1.00 39.05 ? 62 GLU H OE2 1 ATOM 5233 N N . PHE C 3 64 ? 64.584 23.115 95.214 1.00 23.78 ? 63 PHE H N 1 ATOM 5234 C CA . PHE C 3 64 ? 65.294 24.362 95.375 1.00 22.51 ? 63 PHE H CA 1 ATOM 5235 C C . PHE C 3 64 ? 66.781 24.233 95.663 1.00 23.48 ? 63 PHE H C 1 ATOM 5236 O O . PHE C 3 64 ? 67.500 25.255 95.579 1.00 24.53 ? 63 PHE H O 1 ATOM 5237 C CB . PHE C 3 64 ? 64.603 25.159 96.481 1.00 19.79 ? 63 PHE H CB 1 ATOM 5238 C CG . PHE C 3 64 ? 63.228 25.483 95.952 1.00 18.87 ? 63 PHE H CG 1 ATOM 5239 C CD1 . PHE C 3 64 ? 63.084 26.529 95.053 1.00 17.44 ? 63 PHE H CD1 1 ATOM 5240 C CD2 . PHE C 3 64 ? 62.164 24.660 96.268 1.00 17.66 ? 63 PHE H CD2 1 ATOM 5241 C CE1 . PHE C 3 64 ? 61.868 26.754 94.450 1.00 18.01 ? 63 PHE H CE1 1 ATOM 5242 C CE2 . PHE C 3 64 ? 60.953 24.889 95.661 1.00 18.44 ? 63 PHE H CE2 1 ATOM 5243 C CZ . PHE C 3 64 ? 60.804 25.928 94.754 1.00 17.67 ? 63 PHE H CZ 1 ATOM 5244 N N . LYS C 3 65 ? 67.255 22.994 95.943 1.00 24.15 ? 64 LYS H N 1 ATOM 5245 C CA . LYS C 3 65 ? 68.658 22.738 96.279 1.00 25.33 ? 64 LYS H CA 1 ATOM 5246 C C . LYS C 3 65 ? 69.359 22.941 94.950 1.00 26.07 ? 64 LYS H C 1 ATOM 5247 O O . LYS C 3 65 ? 69.049 22.248 93.973 1.00 26.59 ? 64 LYS H O 1 ATOM 5248 C CB . LYS C 3 65 ? 68.798 21.310 96.798 1.00 23.83 ? 64 LYS H CB 1 ATOM 5249 C CG . LYS C 3 65 ? 70.056 21.084 97.616 1.00 22.71 ? 64 LYS H CG 1 ATOM 5250 C CD . LYS C 3 65 ? 69.944 19.765 98.368 1.00 21.95 ? 64 LYS H CD 1 ATOM 5251 C CE . LYS C 3 65 ? 71.204 19.473 99.163 1.00 21.50 ? 64 LYS H CE 1 ATOM 5252 N NZ . LYS C 3 65 ? 71.059 18.206 99.853 1.00 21.27 ? 64 LYS H NZ 1 ATOM 5253 N N . GLY C 3 66 ? 70.209 23.970 94.849 1.00 24.22 ? 65 GLY H N 1 ATOM 5254 C CA . GLY C 3 66 ? 70.847 24.211 93.577 1.00 22.55 ? 65 GLY H CA 1 ATOM 5255 C C . GLY C 3 66 ? 71.007 25.671 93.225 1.00 23.63 ? 65 GLY H C 1 ATOM 5256 O O . GLY C 3 66 ? 72.132 26.145 93.184 1.00 24.12 ? 65 GLY H O 1 ATOM 5257 N N . ARG C 3 67 ? 69.973 26.448 92.928 1.00 23.07 ? 66 ARG H N 1 ATOM 5258 C CA . ARG C 3 67 ? 70.232 27.819 92.540 1.00 22.64 ? 66 ARG H CA 1 ATOM 5259 C C . ARG C 3 67 ? 69.880 28.793 93.618 1.00 22.31 ? 66 ARG H C 1 ATOM 5260 O O . ARG C 3 67 ? 70.345 29.923 93.576 1.00 23.12 ? 66 ARG H O 1 ATOM 5261 C CB . ARG C 3 67 ? 69.456 28.128 91.278 1.00 23.15 ? 66 ARG H CB 1 ATOM 5262 C CG . ARG C 3 67 ? 69.848 27.146 90.187 1.00 24.10 ? 66 ARG H CG 1 ATOM 5263 C CD . ARG C 3 67 ? 69.166 27.289 88.845 1.00 24.56 ? 66 ARG H CD 1 ATOM 5264 N NE . ARG C 3 67 ? 67.755 26.916 88.845 1.00 23.23 ? 66 ARG H NE 1 ATOM 5265 C CZ . ARG C 3 67 ? 66.819 27.833 88.608 1.00 24.10 ? 66 ARG H CZ 1 ATOM 5266 N NH1 . ARG C 3 67 ? 67.152 29.088 88.323 1.00 23.61 ? 66 ARG H NH1 1 ATOM 5267 N NH2 . ARG C 3 67 ? 65.544 27.488 88.634 1.00 24.50 ? 66 ARG H NH2 1 ATOM 5268 N N . PHE C 3 68 ? 69.033 28.356 94.545 1.00 21.99 ? 67 PHE H N 1 ATOM 5269 C CA . PHE C 3 68 ? 68.563 29.175 95.644 1.00 22.56 ? 67 PHE H CA 1 ATOM 5270 C C . PHE C 3 68 ? 69.616 29.098 96.728 1.00 23.62 ? 67 PHE H C 1 ATOM 5271 O O . PHE C 3 68 ? 70.204 28.024 96.969 1.00 23.33 ? 67 PHE H O 1 ATOM 5272 C CB . PHE C 3 68 ? 67.223 28.635 96.137 1.00 22.47 ? 67 PHE H CB 1 ATOM 5273 C CG . PHE C 3 68 ? 66.273 28.780 94.963 1.00 24.56 ? 67 PHE H CG 1 ATOM 5274 C CD1 . PHE C 3 68 ? 65.709 30.002 94.690 1.00 24.40 ? 67 PHE H CD1 1 ATOM 5275 C CD2 . PHE C 3 68 ? 66.064 27.719 94.101 1.00 24.92 ? 67 PHE H CD2 1 ATOM 5276 C CE1 . PHE C 3 68 ? 64.952 30.164 93.559 1.00 24.06 ? 67 PHE H CE1 1 ATOM 5277 C CE2 . PHE C 3 68 ? 65.311 27.881 92.968 1.00 25.17 ? 67 PHE H CE2 1 ATOM 5278 C CZ . PHE C 3 68 ? 64.759 29.111 92.703 1.00 25.43 ? 67 PHE H CZ 1 ATOM 5279 N N . ALA C 3 69 ? 69.787 30.262 97.368 1.00 22.66 ? 68 ALA H N 1 ATOM 5280 C CA . ALA C 3 69 ? 70.806 30.483 98.373 1.00 21.09 ? 68 ALA H CA 1 ATOM 5281 C C . ALA C 3 69 ? 70.264 31.412 99.463 1.00 20.69 ? 68 ALA H C 1 ATOM 5282 O O . ALA C 3 69 ? 70.009 32.582 99.163 1.00 21.31 ? 68 ALA H O 1 ATOM 5283 C CB . ALA C 3 69 ? 72.042 31.127 97.713 1.00 22.10 ? 68 ALA H CB 1 ATOM 5284 N N . PHE C 3 70 ? 70.048 30.989 100.706 1.00 18.95 ? 69 PHE H N 1 ATOM 5285 C CA . PHE C 3 70 ? 69.517 31.842 101.746 1.00 18.56 ? 69 PHE H CA 1 ATOM 5286 C C . PHE C 3 70 ? 70.683 32.580 102.387 1.00 21.07 ? 69 PHE H C 1 ATOM 5287 O O . PHE C 3 70 ? 71.765 32.006 102.496 1.00 21.43 ? 69 PHE H O 1 ATOM 5288 C CB . PHE C 3 70 ? 68.769 30.956 102.756 1.00 17.80 ? 69 PHE H CB 1 ATOM 5289 C CG . PHE C 3 70 ? 67.575 30.159 102.217 1.00 17.29 ? 69 PHE H CG 1 ATOM 5290 C CD1 . PHE C 3 70 ? 67.034 30.393 100.958 1.00 17.80 ? 69 PHE H CD1 1 ATOM 5291 C CD2 . PHE C 3 70 ? 67.038 29.159 102.988 1.00 15.67 ? 69 PHE H CD2 1 ATOM 5292 C CE1 . PHE C 3 70 ? 65.990 29.634 100.476 1.00 16.71 ? 69 PHE H CE1 1 ATOM 5293 C CE2 . PHE C 3 70 ? 65.990 28.411 102.511 1.00 15.36 ? 69 PHE H CE2 1 ATOM 5294 C CZ . PHE C 3 70 ? 65.471 28.641 101.260 1.00 16.30 ? 69 PHE H CZ 1 ATOM 5295 N N . SER C 3 71 ? 70.584 33.844 102.768 1.00 23.04 ? 70 SER H N 1 ATOM 5296 C CA . SER C 3 71 ? 71.696 34.592 103.361 1.00 24.86 ? 70 SER H CA 1 ATOM 5297 C C . SER C 3 71 ? 71.064 35.602 104.325 1.00 26.63 ? 70 SER H C 1 ATOM 5298 O O . SER C 3 71 ? 69.857 35.861 104.168 1.00 27.09 ? 70 SER H O 1 ATOM 5299 C CB . SER C 3 71 ? 72.445 35.323 102.262 1.00 26.53 ? 70 SER H CB 1 ATOM 5300 O OG . SER C 3 71 ? 72.128 34.783 100.976 1.00 28.85 ? 70 SER H OG 1 ATOM 5301 N N . LEU C 3 72 ? 71.736 36.241 105.296 1.00 28.03 ? 71 LEU H N 1 ATOM 5302 C CA . LEU C 3 72 ? 71.022 37.061 106.267 1.00 27.53 ? 71 LEU H CA 1 ATOM 5303 C C . LEU C 3 72 ? 71.840 38.273 106.660 1.00 28.59 ? 71 LEU H C 1 ATOM 5304 O O . LEU C 3 72 ? 73.040 38.116 106.854 1.00 30.19 ? 71 LEU H O 1 ATOM 5305 C CB . LEU C 3 72 ? 70.714 36.281 107.562 1.00 28.41 ? 71 LEU H CB 1 ATOM 5306 C CG . LEU C 3 72 ? 70.814 34.746 107.646 1.00 28.59 ? 71 LEU H CG 1 ATOM 5307 C CD1 . LEU C 3 72 ? 72.280 34.276 107.695 1.00 29.52 ? 71 LEU H CD1 1 ATOM 5308 C CD2 . LEU C 3 72 ? 70.099 34.297 108.887 1.00 28.04 ? 71 LEU H CD2 1 ATOM 5309 N N . GLU C 3 73 ? 71.340 39.498 106.714 1.00 31.53 ? 72 GLU H N 1 ATOM 5310 C CA . GLU C 3 73 ? 72.078 40.610 107.258 1.00 35.09 ? 72 GLU H CA 1 ATOM 5311 C C . GLU C 3 73 ? 71.406 40.759 108.607 1.00 35.49 ? 72 GLU H C 1 ATOM 5312 O O . GLU C 3 73 ? 70.468 41.528 108.841 1.00 34.71 ? 72 GLU H O 1 ATOM 5313 C CB . GLU C 3 73 ? 71.906 41.908 106.470 1.00 37.14 ? 72 GLU H CB 1 ATOM 5314 C CG . GLU C 3 73 ? 72.630 42.045 105.117 1.00 40.73 ? 72 GLU H CG 1 ATOM 5315 C CD . GLU C 3 73 ? 71.798 41.711 103.861 1.00 43.25 ? 72 GLU H CD 1 ATOM 5316 O OE1 . GLU C 3 73 ? 71.046 42.571 103.351 1.00 43.98 ? 72 GLU H OE1 1 ATOM 5317 O OE2 . GLU C 3 73 ? 71.939 40.581 103.378 1.00 45.67 ? 72 GLU H OE2 1 ATOM 5318 N N . THR C 3 74 ? 71.906 39.933 109.504 1.00 36.83 ? 73 THR H N 1 ATOM 5319 C CA . THR C 3 74 ? 71.468 39.775 110.891 1.00 37.87 ? 73 THR H CA 1 ATOM 5320 C C . THR C 3 74 ? 71.279 41.098 111.625 1.00 37.60 ? 73 THR H C 1 ATOM 5321 O O . THR C 3 74 ? 70.273 41.400 112.276 1.00 37.80 ? 73 THR H O 1 ATOM 5322 C CB . THR C 3 74 ? 72.535 38.848 111.596 1.00 39.21 ? 73 THR H CB 1 ATOM 5323 O OG1 . THR C 3 74 ? 73.799 39.211 111.018 1.00 40.13 ? 73 THR H OG1 1 ATOM 5324 C CG2 . THR C 3 74 ? 72.322 37.335 111.392 1.00 38.33 ? 73 THR H CG2 1 ATOM 5325 N N . SER C 3 75 ? 72.324 41.876 111.357 1.00 39.21 ? 74 SER H N 1 ATOM 5326 C CA . SER C 3 75 ? 72.541 43.217 111.864 1.00 39.10 ? 74 SER H CA 1 ATOM 5327 C C . SER C 3 75 ? 71.483 44.203 111.380 1.00 36.14 ? 74 SER H C 1 ATOM 5328 O O . SER C 3 75 ? 71.269 45.251 111.977 1.00 35.32 ? 74 SER H O 1 ATOM 5329 C CB . SER C 3 75 ? 73.983 43.636 111.435 1.00 39.68 ? 74 SER H CB 1 ATOM 5330 O OG . SER C 3 75 ? 75.036 42.661 111.610 1.00 39.99 ? 74 SER H OG 1 ATOM 5331 N N . ALA C 3 76 ? 70.808 43.925 110.280 1.00 34.19 ? 75 ALA H N 1 ATOM 5332 C CA . ALA C 3 76 ? 69.692 44.771 109.899 1.00 32.23 ? 75 ALA H CA 1 ATOM 5333 C C . ALA C 3 76 ? 68.404 43.936 109.947 1.00 30.11 ? 75 ALA H C 1 ATOM 5334 O O . ALA C 3 76 ? 67.336 44.412 109.545 1.00 30.54 ? 75 ALA H O 1 ATOM 5335 C CB . ALA C 3 76 ? 69.868 45.325 108.474 1.00 33.19 ? 75 ALA H CB 1 ATOM 5336 N N . SER C 3 77 ? 68.463 42.690 110.464 1.00 28.58 ? 76 SER H N 1 ATOM 5337 C CA . SER C 3 77 ? 67.324 41.786 110.501 1.00 25.69 ? 76 SER H CA 1 ATOM 5338 C C . SER C 3 77 ? 66.802 41.557 109.070 1.00 21.33 ? 76 SER H C 1 ATOM 5339 O O . SER C 3 77 ? 65.611 41.744 108.773 1.00 19.88 ? 76 SER H O 1 ATOM 5340 C CB . SER C 3 77 ? 66.178 42.377 111.409 1.00 25.24 ? 76 SER H CB 1 ATOM 5341 O OG . SER C 3 77 ? 66.586 42.860 112.678 1.00 25.64 ? 76 SER H OG 1 ATOM 5342 N N . THR C 3 78 ? 67.642 41.169 108.122 1.00 20.76 ? 77 THR H N 1 ATOM 5343 C CA . THR C 3 78 ? 67.175 40.951 106.761 1.00 21.17 ? 77 THR H CA 1 ATOM 5344 C C . THR C 3 78 ? 67.582 39.587 106.223 1.00 20.09 ? 77 THR H C 1 ATOM 5345 O O . THR C 3 78 ? 68.727 39.196 106.403 1.00 21.36 ? 77 THR H O 1 ATOM 5346 C CB . THR C 3 78 ? 67.724 42.086 105.892 1.00 21.05 ? 77 THR H CB 1 ATOM 5347 O OG1 . THR C 3 78 ? 67.397 43.315 106.545 1.00 22.36 ? 77 THR H OG1 1 ATOM 5348 C CG2 . THR C 3 78 ? 67.150 42.076 104.488 1.00 22.56 ? 77 THR H CG2 1 ATOM 5349 N N . ALA C 3 79 ? 66.636 38.835 105.658 1.00 19.23 ? 78 ALA H N 1 ATOM 5350 C CA . ALA C 3 79 ? 66.830 37.552 104.999 1.00 20.05 ? 78 ALA H CA 1 ATOM 5351 C C . ALA C 3 79 ? 66.796 37.865 103.521 1.00 20.37 ? 78 ALA H C 1 ATOM 5352 O O . ALA C 3 79 ? 66.060 38.771 103.113 1.00 23.41 ? 78 ALA H O 1 ATOM 5353 C CB . ALA C 3 79 ? 65.689 36.598 105.262 1.00 19.06 ? 78 ALA H CB 1 ATOM 5354 N N . ASN C 3 80 ? 67.557 37.226 102.669 1.00 20.86 ? 79 ASN H N 1 ATOM 5355 C CA . ASN C 3 80 ? 67.439 37.525 101.270 1.00 20.44 ? 79 ASN H CA 1 ATOM 5356 C C . ASN C 3 80 ? 67.473 36.228 100.504 1.00 21.41 ? 79 ASN H C 1 ATOM 5357 O O . ASN C 3 80 ? 68.162 35.266 100.885 1.00 23.57 ? 79 ASN H O 1 ATOM 5358 C CB . ASN C 3 80 ? 68.574 38.376 100.719 1.00 20.24 ? 79 ASN H CB 1 ATOM 5359 C CG . ASN C 3 80 ? 69.442 39.114 101.719 1.00 20.02 ? 79 ASN H CG 1 ATOM 5360 O OD1 . ASN C 3 80 ? 70.493 38.604 102.096 1.00 21.27 ? 79 ASN H OD1 1 ATOM 5361 N ND2 . ASN C 3 80 ? 69.087 40.295 102.221 1.00 18.04 ? 79 ASN H ND2 1 ATOM 5362 N N . LEU C 3 81 ? 66.657 36.140 99.466 1.00 21.11 ? 80 LEU H N 1 ATOM 5363 C CA . LEU C 3 81 ? 66.668 34.961 98.644 1.00 21.46 ? 80 LEU H CA 1 ATOM 5364 C C . LEU C 3 81 ? 67.537 35.381 97.500 1.00 21.89 ? 80 LEU H C 1 ATOM 5365 O O . LEU C 3 81 ? 67.272 36.421 96.882 1.00 21.60 ? 80 LEU H O 1 ATOM 5366 C CB . LEU C 3 81 ? 65.282 34.607 98.075 1.00 20.99 ? 80 LEU H CB 1 ATOM 5367 C CG . LEU C 3 81 ? 65.124 33.476 97.035 1.00 19.68 ? 80 LEU H CG 1 ATOM 5368 C CD1 . LEU C 3 81 ? 65.631 32.180 97.630 1.00 19.66 ? 80 LEU H CD1 1 ATOM 5369 C CD2 . LEU C 3 81 ? 63.655 33.280 96.654 1.00 19.50 ? 80 LEU H CD2 1 ATOM 5370 N N . GLN C 3 82 ? 68.585 34.632 97.224 1.00 22.45 ? 81 GLN H N 1 ATOM 5371 C CA . GLN C 3 82 ? 69.322 34.894 96.019 1.00 24.74 ? 81 GLN H CA 1 ATOM 5372 C C . GLN C 3 82 ? 69.078 33.686 95.154 1.00 24.09 ? 81 GLN H C 1 ATOM 5373 O O . GLN C 3 82 ? 69.169 32.546 95.640 1.00 22.17 ? 81 GLN H O 1 ATOM 5374 C CB . GLN C 3 82 ? 70.762 35.032 96.325 1.00 27.81 ? 81 GLN H CB 1 ATOM 5375 C CG . GLN C 3 82 ? 71.560 35.515 95.121 1.00 30.65 ? 81 GLN H CG 1 ATOM 5376 C CD . GLN C 3 82 ? 73.045 35.523 95.457 1.00 33.55 ? 81 GLN H CD 1 ATOM 5377 O OE1 . GLN C 3 82 ? 73.572 36.502 95.988 1.00 36.58 ? 81 GLN H OE1 1 ATOM 5378 N NE2 . GLN C 3 82 ? 73.796 34.448 95.207 1.00 33.40 ? 81 GLN H NE2 1 ATOM 5379 N N . ILE C 3 83 ? 68.630 33.997 93.935 1.00 25.08 ? 82 ILE H N 1 ATOM 5380 C CA . ILE C 3 83 ? 68.405 33.026 92.861 1.00 26.54 ? 82 ILE H CA 1 ATOM 5381 C C . ILE C 3 83 ? 69.453 33.237 91.757 1.00 30.10 ? 82 ILE H C 1 ATOM 5382 O O . ILE C 3 83 ? 69.596 34.355 91.203 1.00 29.28 ? 82 ILE H O 1 ATOM 5383 C CB . ILE C 3 83 ? 67.081 33.202 92.181 1.00 26.01 ? 82 ILE H CB 1 ATOM 5384 C CG1 . ILE C 3 83 ? 65.945 33.475 93.170 1.00 28.36 ? 82 ILE H CG1 1 ATOM 5385 C CG2 . ILE C 3 83 ? 66.917 31.964 91.329 1.00 25.95 ? 82 ILE H CG2 1 ATOM 5386 C CD1 . ILE C 3 83 ? 64.607 34.093 92.641 1.00 27.87 ? 82 ILE H CD1 1 ATOM 5387 N N . ASN C 3 84 A 70.204 32.194 91.399 1.00 30.91 ? 82 ASN H N 1 ATOM 5388 C CA . ASN C 3 84 A 71.208 32.340 90.347 1.00 31.87 ? 82 ASN H CA 1 ATOM 5389 C C . ASN C 3 84 A 70.829 31.567 89.093 1.00 33.21 ? 82 ASN H C 1 ATOM 5390 O O . ASN C 3 84 A 70.257 30.469 89.187 1.00 32.81 ? 82 ASN H O 1 ATOM 5391 C CB . ASN C 3 84 A 72.571 31.843 90.845 1.00 32.46 ? 82 ASN H CB 1 ATOM 5392 C CG . ASN C 3 84 A 73.200 32.763 91.902 1.00 33.95 ? 82 ASN H CG 1 ATOM 5393 O OD1 . ASN C 3 84 A 72.929 32.683 93.120 1.00 34.49 ? 82 ASN H OD1 1 ATOM 5394 N ND2 . ASN C 3 84 A 74.070 33.688 91.485 1.00 33.42 ? 82 ASN H ND2 1 ATOM 5395 N N . ASN C 3 85 B 71.165 32.159 87.926 1.00 34.21 ? 82 ASN H N 1 ATOM 5396 C CA . ASN C 3 85 B 70.893 31.619 86.583 1.00 33.05 ? 82 ASN H CA 1 ATOM 5397 C C . ASN C 3 85 B 69.381 31.431 86.392 1.00 31.46 ? 82 ASN H C 1 ATOM 5398 O O . ASN C 3 85 B 68.793 30.338 86.372 1.00 30.52 ? 82 ASN H O 1 ATOM 5399 C CB . ASN C 3 85 B 71.617 30.259 86.342 1.00 34.81 ? 82 ASN H CB 1 ATOM 5400 C CG . ASN C 3 85 B 71.308 29.637 84.961 1.00 37.43 ? 82 ASN H CG 1 ATOM 5401 O OD1 . ASN C 3 85 B 71.960 29.925 83.944 1.00 39.13 ? 82 ASN H OD1 1 ATOM 5402 N ND2 . ASN C 3 85 B 70.281 28.794 84.811 1.00 38.47 ? 82 ASN H ND2 1 ATOM 5403 N N . LEU C 3 86 C 68.721 32.571 86.213 1.00 31.10 ? 82 LEU H N 1 ATOM 5404 C CA . LEU C 3 86 C 67.265 32.609 86.220 1.00 32.05 ? 82 LEU H CA 1 ATOM 5405 C C . LEU C 3 86 C 66.557 31.849 85.113 1.00 32.51 ? 82 LEU H C 1 ATOM 5406 O O . LEU C 3 86 C 66.250 32.395 84.061 1.00 33.55 ? 82 LEU H O 1 ATOM 5407 C CB . LEU C 3 86 C 66.840 34.088 86.245 1.00 30.86 ? 82 LEU H CB 1 ATOM 5408 C CG . LEU C 3 86 C 67.203 34.897 87.516 1.00 29.56 ? 82 LEU H CG 1 ATOM 5409 C CD1 . LEU C 3 86 C 66.917 36.363 87.292 1.00 28.19 ? 82 LEU H CD1 1 ATOM 5410 C CD2 . LEU C 3 86 C 66.428 34.378 88.712 1.00 29.40 ? 82 LEU H CD2 1 ATOM 5411 N N . LYS C 3 87 ? 66.380 30.547 85.282 1.00 31.41 ? 83 LYS H N 1 ATOM 5412 C CA . LYS C 3 87 ? 65.610 29.715 84.386 1.00 32.35 ? 83 LYS H CA 1 ATOM 5413 C C . LYS C 3 87 ? 64.205 30.278 84.382 1.00 34.93 ? 83 LYS H C 1 ATOM 5414 O O . LYS C 3 87 ? 63.654 30.499 85.461 1.00 33.42 ? 83 LYS H O 1 ATOM 5415 C CB . LYS C 3 87 ? 65.566 28.321 84.907 1.00 33.36 ? 83 LYS H CB 1 ATOM 5416 C CG . LYS C 3 87 ? 66.616 27.377 84.329 1.00 36.29 ? 83 LYS H CG 1 ATOM 5417 C CD . LYS C 3 87 ? 66.511 25.975 84.970 1.00 38.16 ? 83 LYS H CD 1 ATOM 5418 C CE . LYS C 3 87 ? 65.101 25.321 84.861 1.00 38.27 ? 83 LYS H CE 1 ATOM 5419 N NZ . LYS C 3 87 ? 64.923 24.218 85.799 1.00 39.02 ? 83 LYS H NZ 1 ATOM 5420 N N . ASN C 3 88 ? 63.588 30.503 83.220 1.00 37.53 ? 84 ASN H N 1 ATOM 5421 C CA . ASN C 3 88 ? 62.250 31.113 83.093 1.00 40.99 ? 84 ASN H CA 1 ATOM 5422 C C . ASN C 3 88 ? 61.104 30.747 84.057 1.00 40.91 ? 84 ASN H C 1 ATOM 5423 O O . ASN C 3 88 ? 60.288 31.603 84.413 1.00 43.02 ? 84 ASN H O 1 ATOM 5424 C CB . ASN C 3 88 ? 61.693 30.880 81.672 1.00 42.64 ? 84 ASN H CB 1 ATOM 5425 C CG . ASN C 3 88 ? 61.259 29.442 81.331 1.00 44.83 ? 84 ASN H CG 1 ATOM 5426 O OD1 . ASN C 3 88 ? 61.138 28.510 82.149 1.00 45.87 ? 84 ASN H OD1 1 ATOM 5427 N ND2 . ASN C 3 88 ? 61.059 29.226 80.035 1.00 45.17 ? 84 ASN H ND2 1 ATOM 5428 N N . GLU C 3 89 ? 60.995 29.501 84.515 1.00 37.29 ? 85 GLU H N 1 ATOM 5429 C CA . GLU C 3 89 ? 59.977 29.059 85.451 1.00 34.56 ? 85 GLU H CA 1 ATOM 5430 C C . GLU C 3 89 ? 60.177 29.599 86.870 1.00 34.42 ? 85 GLU H C 1 ATOM 5431 O O . GLU C 3 89 ? 59.680 29.047 87.857 1.00 34.91 ? 85 GLU H O 1 ATOM 5432 C CB . GLU C 3 89 ? 59.971 27.527 85.426 1.00 34.93 ? 85 GLU H CB 1 ATOM 5433 C CG . GLU C 3 89 ? 61.325 26.860 85.686 1.00 34.28 ? 85 GLU H CG 1 ATOM 5434 C CD . GLU C 3 89 ? 61.340 25.384 85.323 1.00 34.10 ? 85 GLU H CD 1 ATOM 5435 O OE1 . GLU C 3 89 ? 60.876 24.575 86.127 1.00 34.00 ? 85 GLU H OE1 1 ATOM 5436 O OE2 . GLU C 3 89 ? 61.813 25.043 84.239 1.00 33.92 ? 85 GLU H OE2 1 ATOM 5437 N N . ASP C 3 90 ? 61.056 30.599 86.982 1.00 34.04 ? 86 ASP H N 1 ATOM 5438 C CA . ASP C 3 90 ? 61.222 31.380 88.181 1.00 31.43 ? 86 ASP H CA 1 ATOM 5439 C C . ASP C 3 90 ? 60.370 32.655 88.092 1.00 31.20 ? 86 ASP H C 1 ATOM 5440 O O . ASP C 3 90 ? 60.484 33.603 88.880 1.00 32.20 ? 86 ASP H O 1 ATOM 5441 C CB . ASP C 3 90 ? 62.701 31.661 88.310 1.00 29.62 ? 86 ASP H CB 1 ATOM 5442 C CG . ASP C 3 90 ? 63.555 30.413 88.464 1.00 27.29 ? 86 ASP H CG 1 ATOM 5443 O OD1 . ASP C 3 90 ? 63.081 29.307 88.708 1.00 25.42 ? 86 ASP H OD1 1 ATOM 5444 O OD2 . ASP C 3 90 ? 64.745 30.572 88.319 1.00 26.25 ? 86 ASP H OD2 1 ATOM 5445 N N . LYS C 3 91 ? 59.500 32.733 87.081 1.00 30.95 ? 87 LYS H N 1 ATOM 5446 C CA . LYS C 3 91 ? 58.489 33.760 87.007 1.00 30.35 ? 87 LYS H CA 1 ATOM 5447 C C . LYS C 3 91 ? 57.485 33.218 88.021 1.00 27.29 ? 87 LYS H C 1 ATOM 5448 O O . LYS C 3 91 ? 56.877 32.154 87.816 1.00 24.71 ? 87 LYS H O 1 ATOM 5449 C CB . LYS C 3 91 ? 57.904 33.813 85.604 1.00 31.12 ? 87 LYS H CB 1 ATOM 5450 C CG . LYS C 3 91 ? 57.276 35.148 85.324 1.00 34.70 ? 87 LYS H CG 1 ATOM 5451 C CD . LYS C 3 91 ? 55.942 35.369 86.046 1.00 38.22 ? 87 LYS H CD 1 ATOM 5452 C CE . LYS C 3 91 ? 55.512 36.857 85.973 1.00 39.75 ? 87 LYS H CE 1 ATOM 5453 N NZ . LYS C 3 91 ? 54.204 37.030 85.356 1.00 39.37 ? 87 LYS H NZ 1 ATOM 5454 N N . ALA C 3 92 ? 57.384 33.950 89.139 1.00 24.82 ? 88 ALA H N 1 ATOM 5455 C CA . ALA C 3 92 ? 56.493 33.638 90.265 1.00 22.08 ? 88 ALA H CA 1 ATOM 5456 C C . ALA C 3 92 ? 56.658 34.748 91.291 1.00 21.37 ? 88 ALA H C 1 ATOM 5457 O O . ALA C 3 92 ? 57.371 35.733 91.008 1.00 21.33 ? 88 ALA H O 1 ATOM 5458 C CB . ALA C 3 92 ? 56.858 32.324 90.975 1.00 19.49 ? 88 ALA H CB 1 ATOM 5459 N N . THR C 3 93 ? 55.968 34.605 92.443 1.00 20.14 ? 89 THR H N 1 ATOM 5460 C CA . THR C 3 93 ? 56.069 35.543 93.552 1.00 18.76 ? 89 THR H CA 1 ATOM 5461 C C . THR C 3 93 ? 56.594 34.815 94.776 1.00 17.96 ? 89 THR H C 1 ATOM 5462 O O . THR C 3 93 ? 56.178 33.703 95.112 1.00 18.63 ? 89 THR H O 1 ATOM 5463 C CB . THR C 3 93 ? 54.701 36.184 93.844 1.00 17.28 ? 89 THR H CB 1 ATOM 5464 O OG1 . THR C 3 93 ? 54.465 37.079 92.762 1.00 16.34 ? 89 THR H OG1 1 ATOM 5465 C CG2 . THR C 3 93 ? 54.662 37.027 95.090 1.00 16.51 ? 89 THR H CG2 1 ATOM 5466 N N . PHE C 3 94 ? 57.608 35.431 95.367 1.00 17.94 ? 90 PHE H N 1 ATOM 5467 C CA . PHE C 3 94 ? 58.286 34.873 96.503 1.00 16.55 ? 90 PHE H CA 1 ATOM 5468 C C . PHE C 3 94 ? 57.912 35.594 97.786 1.00 14.92 ? 90 PHE H C 1 ATOM 5469 O O . PHE C 3 94 ? 58.035 36.812 97.891 1.00 14.55 ? 90 PHE H O 1 ATOM 5470 C CB . PHE C 3 94 ? 59.767 34.960 96.189 1.00 17.38 ? 90 PHE H CB 1 ATOM 5471 C CG . PHE C 3 94 ? 60.131 34.070 95.002 1.00 15.16 ? 90 PHE H CG 1 ATOM 5472 C CD1 . PHE C 3 94 ? 59.996 32.696 95.106 1.00 15.75 ? 90 PHE H CD1 1 ATOM 5473 C CD2 . PHE C 3 94 ? 60.584 34.618 93.817 1.00 15.74 ? 90 PHE H CD2 1 ATOM 5474 C CE1 . PHE C 3 94 ? 60.303 31.895 94.029 1.00 15.97 ? 90 PHE H CE1 1 ATOM 5475 C CE2 . PHE C 3 94 ? 60.886 33.814 92.741 1.00 15.71 ? 90 PHE H CE2 1 ATOM 5476 C CZ . PHE C 3 94 ? 60.749 32.453 92.853 1.00 14.74 ? 90 PHE H CZ 1 ATOM 5477 N N . PHE C 3 95 ? 57.326 34.837 98.725 1.00 15.46 ? 91 PHE H N 1 ATOM 5478 C CA . PHE C 3 95 ? 56.945 35.298 100.068 1.00 12.07 ? 91 PHE H CA 1 ATOM 5479 C C . PHE C 3 95 ? 57.958 34.827 101.086 1.00 11.26 ? 91 PHE H C 1 ATOM 5480 O O . PHE C 3 95 ? 58.457 33.714 100.950 1.00 10.99 ? 91 PHE H O 1 ATOM 5481 C CB . PHE C 3 95 ? 55.628 34.733 100.522 1.00 8.55 ? 91 PHE H CB 1 ATOM 5482 C CG . PHE C 3 95 ? 54.487 35.263 99.672 1.00 8.30 ? 91 PHE H CG 1 ATOM 5483 C CD1 . PHE C 3 95 ? 54.014 36.539 99.890 1.00 7.70 ? 91 PHE H CD1 1 ATOM 5484 C CD2 . PHE C 3 95 ? 53.886 34.454 98.717 1.00 7.64 ? 91 PHE H CD2 1 ATOM 5485 C CE1 . PHE C 3 95 ? 52.955 37.006 99.162 1.00 7.41 ? 91 PHE H CE1 1 ATOM 5486 C CE2 . PHE C 3 95 ? 52.813 34.944 97.986 1.00 9.27 ? 91 PHE H CE2 1 ATOM 5487 C CZ . PHE C 3 95 ? 52.348 36.214 98.218 1.00 7.29 ? 91 PHE H CZ 1 ATOM 5488 N N . CYS C 3 96 ? 58.344 35.666 102.051 1.00 9.24 ? 92 CYS H N 1 ATOM 5489 C CA . CYS C 3 96 ? 59.193 35.256 103.163 1.00 6.89 ? 92 CYS H CA 1 ATOM 5490 C C . CYS C 3 96 ? 58.184 35.391 104.269 1.00 5.51 ? 92 CYS H C 1 ATOM 5491 O O . CYS C 3 96 ? 57.326 36.286 104.196 1.00 3.46 ? 92 CYS H O 1 ATOM 5492 C CB . CYS C 3 96 ? 60.371 36.213 103.408 1.00 6.67 ? 92 CYS H CB 1 ATOM 5493 S SG . CYS C 3 96 ? 59.799 37.867 103.827 1.00 7.86 ? 92 CYS H SG 1 ATOM 5494 N N . ALA C 3 97 ? 58.288 34.458 105.198 1.00 4.10 ? 93 ALA H N 1 ATOM 5495 C CA . ALA C 3 97 ? 57.372 34.342 106.290 1.00 6.05 ? 93 ALA H CA 1 ATOM 5496 C C . ALA C 3 97 ? 58.143 33.872 107.509 1.00 7.04 ? 93 ALA H C 1 ATOM 5497 O O . ALA C 3 97 ? 59.142 33.155 107.388 1.00 7.51 ? 93 ALA H O 1 ATOM 5498 C CB . ALA C 3 97 ? 56.310 33.317 105.976 1.00 7.03 ? 93 ALA H CB 1 ATOM 5499 N N . ARG C 3 98 ? 57.729 34.327 108.689 1.00 5.89 ? 94 ARG H N 1 ATOM 5500 C CA . ARG C 3 98 ? 58.353 33.981 109.938 1.00 5.45 ? 94 ARG H CA 1 ATOM 5501 C C . ARG C 3 98 ? 57.800 32.624 110.315 1.00 7.75 ? 94 ARG H C 1 ATOM 5502 O O . ARG C 3 98 ? 56.580 32.322 110.407 1.00 5.65 ? 94 ARG H O 1 ATOM 5503 C CB . ARG C 3 98 ? 57.979 34.964 110.994 1.00 4.37 ? 94 ARG H CB 1 ATOM 5504 C CG . ARG C 3 98 ? 58.496 34.770 112.397 1.00 4.24 ? 94 ARG H CG 1 ATOM 5505 C CD . ARG C 3 98 ? 57.326 35.444 112.993 1.00 2.89 ? 94 ARG H CD 1 ATOM 5506 N NE . ARG C 3 98 ? 57.639 35.992 114.273 1.00 4.28 ? 94 ARG H NE 1 ATOM 5507 C CZ . ARG C 3 98 ? 56.884 35.698 115.316 1.00 2.00 ? 94 ARG H CZ 1 ATOM 5508 N NH1 . ARG C 3 98 ? 55.949 34.768 115.225 1.00 2.00 ? 94 ARG H NH1 1 ATOM 5509 N NH2 . ARG C 3 98 ? 57.109 36.252 116.484 1.00 4.03 ? 94 ARG H NH2 1 ATOM 5510 N N . GLY C 3 99 ? 58.826 31.791 110.457 1.00 7.37 ? 95 GLY H N 1 ATOM 5511 C CA . GLY C 3 99 ? 58.581 30.471 110.941 1.00 6.90 ? 95 GLY H CA 1 ATOM 5512 C C . GLY C 3 99 ? 58.529 30.588 112.431 1.00 7.78 ? 95 GLY H C 1 ATOM 5513 O O . GLY C 3 99 ? 59.572 30.853 113.043 1.00 12.44 ? 95 GLY H O 1 ATOM 5514 N N . GLU C 3 100 ? 57.319 30.376 112.945 1.00 7.30 ? 96 GLU H N 1 ATOM 5515 C CA . GLU C 3 100 ? 56.969 30.327 114.372 1.00 8.37 ? 96 GLU H CA 1 ATOM 5516 C C . GLU C 3 100 ? 57.877 29.447 115.237 1.00 9.95 ? 96 GLU H C 1 ATOM 5517 O O . GLU C 3 100 ? 58.452 29.798 116.275 1.00 8.86 ? 96 GLU H O 1 ATOM 5518 C CB . GLU C 3 100 ? 55.543 29.794 114.510 1.00 10.01 ? 96 GLU H CB 1 ATOM 5519 C CG . GLU C 3 100 ? 54.790 29.974 115.835 1.00 8.54 ? 96 GLU H CG 1 ATOM 5520 C CD . GLU C 3 100 ? 55.075 28.964 116.936 1.00 10.53 ? 96 GLU H CD 1 ATOM 5521 O OE1 . GLU C 3 100 ? 54.979 27.756 116.676 1.00 10.94 ? 96 GLU H OE1 1 ATOM 5522 O OE2 . GLU C 3 100 ? 55.364 29.410 118.057 1.00 12.25 ? 96 GLU H OE2 1 ATOM 5523 N N . ASP C 3 101 ? 57.817 28.175 114.858 1.00 9.96 ? 97 ASP H N 1 ATOM 5524 C CA . ASP C 3 101 ? 58.551 27.146 115.573 1.00 9.68 ? 97 ASP H CA 1 ATOM 5525 C C . ASP C 3 101 ? 59.871 26.847 114.876 1.00 9.91 ? 97 ASP H C 1 ATOM 5526 O O . ASP C 3 101 ? 60.162 27.437 113.812 1.00 12.51 ? 97 ASP H O 1 ATOM 5527 C CB . ASP C 3 101 ? 57.697 25.919 115.638 1.00 8.88 ? 97 ASP H CB 1 ATOM 5528 C CG . ASP C 3 101 ? 57.380 25.185 114.340 1.00 9.89 ? 97 ASP H CG 1 ATOM 5529 O OD1 . ASP C 3 101 ? 57.179 25.863 113.321 1.00 8.75 ? 97 ASP H OD1 1 ATOM 5530 O OD2 . ASP C 3 101 ? 57.354 23.940 114.365 1.00 10.13 ? 97 ASP H OD2 1 ATOM 5531 N N . ASN C 3 102 ? 60.620 25.906 115.472 1.00 8.64 ? 98 ASN H N 1 ATOM 5532 C CA . ASN C 3 102 ? 61.896 25.458 114.892 1.00 9.92 ? 98 ASN H CA 1 ATOM 5533 C C . ASN C 3 102 ? 61.630 24.764 113.578 1.00 8.08 ? 98 ASN H C 1 ATOM 5534 O O . ASN C 3 102 ? 60.639 24.044 113.586 1.00 9.52 ? 98 ASN H O 1 ATOM 5535 C CB . ASN C 3 102 ? 62.652 24.452 115.780 1.00 7.38 ? 98 ASN H CB 1 ATOM 5536 C CG . ASN C 3 102 ? 64.080 24.153 115.301 1.00 4.64 ? 98 ASN H CG 1 ATOM 5537 O OD1 . ASN C 3 102 ? 64.685 24.883 114.509 1.00 5.72 ? 98 ASN H OD1 1 ATOM 5538 N ND2 . ASN C 3 102 ? 64.701 23.091 115.778 1.00 2.00 ? 98 ASN H ND2 1 ATOM 5539 N N . PHE C 3 103 ? 62.446 24.863 112.507 1.00 11.75 ? 99 PHE H N 1 ATOM 5540 C CA . PHE C 3 103 ? 62.133 24.326 111.165 1.00 16.76 ? 99 PHE H CA 1 ATOM 5541 C C . PHE C 3 103 ? 61.037 24.971 110.327 1.00 17.00 ? 99 PHE H C 1 ATOM 5542 O O . PHE C 3 103 ? 60.857 24.593 109.157 1.00 19.13 ? 99 PHE H O 1 ATOM 5543 C CB . PHE C 3 103 ? 61.722 22.847 111.137 1.00 20.60 ? 99 PHE H CB 1 ATOM 5544 C CG . PHE C 3 103 ? 62.899 21.961 110.913 1.00 25.07 ? 99 PHE H CG 1 ATOM 5545 C CD1 . PHE C 3 103 ? 64.074 22.184 111.587 1.00 26.68 ? 99 PHE H CD1 1 ATOM 5546 C CD2 . PHE C 3 103 ? 62.761 20.926 110.035 1.00 27.67 ? 99 PHE H CD2 1 ATOM 5547 C CE1 . PHE C 3 103 ? 65.134 21.351 111.381 1.00 28.14 ? 99 PHE H CE1 1 ATOM 5548 C CE2 . PHE C 3 103 ? 63.830 20.083 109.831 1.00 31.14 ? 99 PHE H CE2 1 ATOM 5549 C CZ . PHE C 3 103 ? 65.014 20.299 110.504 1.00 30.67 ? 99 PHE H CZ 1 ATOM 5550 N N . GLY C 3 104 ? 60.225 25.819 110.959 1.00 15.48 ? 100 GLY H N 1 ATOM 5551 C CA . GLY C 3 104 ? 59.217 26.576 110.248 1.00 14.27 ? 100 GLY H CA 1 ATOM 5552 C C . GLY C 3 104 ? 57.976 25.850 109.759 1.00 11.46 ? 100 GLY H C 1 ATOM 5553 O O . GLY C 3 104 ? 57.486 26.173 108.676 1.00 11.59 ? 100 GLY H O 1 ATOM 5554 N N . SER C 3 105 A 57.401 24.951 110.562 1.00 12.49 ? 100 SER H N 1 ATOM 5555 C CA . SER C 3 105 A 56.191 24.275 110.168 1.00 11.77 ? 100 SER H CA 1 ATOM 5556 C C . SER C 3 105 A 55.048 25.274 110.186 1.00 13.13 ? 100 SER H C 1 ATOM 5557 O O . SER C 3 105 A 54.263 25.339 109.239 1.00 13.75 ? 100 SER H O 1 ATOM 5558 C CB . SER C 3 105 A 55.931 23.110 111.123 1.00 11.05 ? 100 SER H CB 1 ATOM 5559 O OG . SER C 3 105 A 55.581 23.513 112.432 1.00 12.35 ? 100 SER H OG 1 ATOM 5560 N N . LEU C 3 106 B 54.925 26.039 111.265 1.00 14.51 ? 100 LEU H N 1 ATOM 5561 C CA . LEU C 3 106 B 53.953 27.115 111.319 1.00 11.89 ? 100 LEU H CA 1 ATOM 5562 C C . LEU C 3 106 B 54.463 28.412 110.745 1.00 12.72 ? 100 LEU H C 1 ATOM 5563 O O . LEU C 3 106 B 55.405 28.970 111.317 1.00 12.65 ? 100 LEU H O 1 ATOM 5564 C CB . LEU C 3 106 B 53.536 27.390 112.738 1.00 11.73 ? 100 LEU H CB 1 ATOM 5565 C CG . LEU C 3 106 B 52.125 27.080 113.106 1.00 12.37 ? 100 LEU H CG 1 ATOM 5566 C CD1 . LEU C 3 106 B 52.028 25.642 113.508 1.00 12.76 ? 100 LEU H CD1 1 ATOM 5567 C CD2 . LEU C 3 106 B 51.713 27.927 114.281 1.00 14.11 ? 100 LEU H CD2 1 ATOM 5568 N N . SER C 3 107 C 53.929 28.901 109.633 1.00 11.38 ? 100 SER H N 1 ATOM 5569 C CA . SER C 3 107 C 54.299 30.239 109.173 1.00 12.20 ? 100 SER H CA 1 ATOM 5570 C C . SER C 3 107 C 53.194 31.172 109.693 1.00 14.61 ? 100 SER H C 1 ATOM 5571 O O . SER C 3 107 C 52.015 31.083 109.267 1.00 15.18 ? 100 SER H O 1 ATOM 5572 C CB . SER C 3 107 C 54.351 30.316 107.647 1.00 11.40 ? 100 SER H CB 1 ATOM 5573 O OG . SER C 3 107 C 55.298 29.414 107.090 1.00 9.91 ? 100 SER H OG 1 ATOM 5574 N N . ASP C 3 108 ? 53.513 32.018 110.671 1.00 13.58 ? 101 ASP H N 1 ATOM 5575 C CA . ASP C 3 108 ? 52.534 32.950 111.187 1.00 15.30 ? 101 ASP H CA 1 ATOM 5576 C C . ASP C 3 108 ? 53.191 34.221 110.745 1.00 19.07 ? 101 ASP H C 1 ATOM 5577 O O . ASP C 3 108 ? 54.418 34.268 110.811 1.00 23.75 ? 101 ASP H O 1 ATOM 5578 C CB . ASP C 3 108 ? 52.454 32.814 112.701 1.00 16.12 ? 101 ASP H CB 1 ATOM 5579 C CG . ASP C 3 108 ? 53.651 33.024 113.629 1.00 16.33 ? 101 ASP H CG 1 ATOM 5580 O OD1 . ASP C 3 108 ? 54.786 33.181 113.167 1.00 18.11 ? 101 ASP H OD1 1 ATOM 5581 O OD2 . ASP C 3 108 ? 53.417 33.065 114.847 1.00 16.10 ? 101 ASP H OD2 1 ATOM 5582 N N . TYR C 3 109 ? 52.536 35.298 110.345 1.00 18.50 ? 102 TYR H N 1 ATOM 5583 C CA . TYR C 3 109 ? 53.213 36.502 109.807 1.00 16.27 ? 102 TYR H CA 1 ATOM 5584 C C . TYR C 3 109 ? 54.199 36.278 108.633 1.00 13.20 ? 102 TYR H C 1 ATOM 5585 O O . TYR C 3 109 ? 55.395 35.979 108.709 1.00 11.97 ? 102 TYR H O 1 ATOM 5586 C CB . TYR C 3 109 ? 53.974 37.253 110.886 1.00 19.85 ? 102 TYR H CB 1 ATOM 5587 C CG . TYR C 3 109 ? 53.240 37.328 112.192 1.00 23.85 ? 102 TYR H CG 1 ATOM 5588 C CD1 . TYR C 3 109 ? 52.081 38.036 112.327 1.00 24.72 ? 102 TYR H CD1 1 ATOM 5589 C CD2 . TYR C 3 109 ? 53.762 36.633 113.249 1.00 26.14 ? 102 TYR H CD2 1 ATOM 5590 C CE1 . TYR C 3 109 ? 51.438 38.046 113.549 1.00 26.48 ? 102 TYR H CE1 1 ATOM 5591 C CE2 . TYR C 3 109 ? 53.119 36.641 114.468 1.00 27.04 ? 102 TYR H CE2 1 ATOM 5592 C CZ . TYR C 3 109 ? 51.960 37.345 114.607 1.00 26.03 ? 102 TYR H CZ 1 ATOM 5593 O OH . TYR C 3 109 ? 51.332 37.324 115.824 1.00 26.27 ? 102 TYR H OH 1 ATOM 5594 N N . TRP C 3 110 ? 53.561 36.598 107.511 1.00 11.56 ? 103 TRP H N 1 ATOM 5595 C CA . TRP C 3 110 ? 54.036 36.558 106.140 1.00 11.26 ? 103 TRP H CA 1 ATOM 5596 C C . TRP C 3 110 ? 54.453 37.931 105.603 1.00 13.38 ? 103 TRP H C 1 ATOM 5597 O O . TRP C 3 110 ? 54.045 38.984 106.083 1.00 15.49 ? 103 TRP H O 1 ATOM 5598 C CB . TRP C 3 110 ? 52.929 36.042 105.265 1.00 6.87 ? 103 TRP H CB 1 ATOM 5599 C CG . TRP C 3 110 ? 52.624 34.585 105.437 1.00 7.24 ? 103 TRP H CG 1 ATOM 5600 C CD1 . TRP C 3 110 ? 52.100 34.058 106.579 1.00 5.19 ? 103 TRP H CD1 1 ATOM 5601 C CD2 . TRP C 3 110 ? 52.810 33.670 104.444 1.00 6.80 ? 103 TRP H CD2 1 ATOM 5602 N NE1 . TRP C 3 110 ? 51.945 32.792 106.294 1.00 4.75 ? 103 TRP H NE1 1 ATOM 5603 C CE2 . TRP C 3 110 ? 52.346 32.521 105.038 1.00 5.56 ? 103 TRP H CE2 1 ATOM 5604 C CE3 . TRP C 3 110 ? 53.289 33.645 103.155 1.00 3.89 ? 103 TRP H CE3 1 ATOM 5605 C CZ2 . TRP C 3 110 ? 52.354 31.339 104.344 1.00 3.67 ? 103 TRP H CZ2 1 ATOM 5606 C CZ3 . TRP C 3 110 ? 53.299 32.455 102.464 1.00 2.73 ? 103 TRP H CZ3 1 ATOM 5607 C CH2 . TRP C 3 110 ? 52.832 31.318 103.057 1.00 2.03 ? 103 TRP H CH2 1 ATOM 5608 N N . GLY C 3 111 ? 55.223 37.962 104.544 1.00 13.60 ? 104 GLY H N 1 ATOM 5609 C CA . GLY C 3 111 ? 55.607 39.204 103.962 1.00 18.15 ? 104 GLY H CA 1 ATOM 5610 C C . GLY C 3 111 ? 54.705 39.393 102.761 1.00 20.10 ? 104 GLY H C 1 ATOM 5611 O O . GLY C 3 111 ? 54.223 38.426 102.178 1.00 18.92 ? 104 GLY H O 1 ATOM 5612 N N . GLN C 3 112 ? 54.499 40.631 102.344 1.00 22.04 ? 105 GLN H N 1 ATOM 5613 C CA . GLN C 3 112 ? 53.753 40.994 101.141 1.00 21.66 ? 105 GLN H CA 1 ATOM 5614 C C . GLN C 3 112 ? 54.160 40.443 99.767 1.00 20.01 ? 105 GLN H C 1 ATOM 5615 O O . GLN C 3 112 ? 53.384 40.626 98.821 1.00 19.06 ? 105 GLN H O 1 ATOM 5616 C CB . GLN C 3 112 ? 53.703 42.500 101.035 1.00 26.97 ? 105 GLN H CB 1 ATOM 5617 C CG . GLN C 3 112 ? 54.932 43.262 101.474 1.00 33.03 ? 105 GLN H CG 1 ATOM 5618 C CD . GLN C 3 112 ? 56.025 43.464 100.458 1.00 38.52 ? 105 GLN H CD 1 ATOM 5619 O OE1 . GLN C 3 112 ? 56.960 44.138 100.834 1.00 43.87 ? 105 GLN H OE1 1 ATOM 5620 N NE2 . GLN C 3 112 ? 56.136 43.015 99.227 1.00 41.80 ? 105 GLN H NE2 1 ATOM 5621 N N . GLY C 3 113 ? 55.351 39.847 99.559 1.00 20.22 ? 106 GLY H N 1 ATOM 5622 C CA . GLY C 3 113 ? 55.677 39.152 98.306 1.00 15.45 ? 106 GLY H CA 1 ATOM 5623 C C . GLY C 3 113 ? 56.511 39.981 97.355 1.00 14.97 ? 106 GLY H C 1 ATOM 5624 O O . GLY C 3 113 ? 56.500 41.222 97.425 1.00 13.34 ? 106 GLY H O 1 ATOM 5625 N N . THR C 3 114 ? 57.285 39.325 96.485 1.00 14.39 ? 107 THR H N 1 ATOM 5626 C CA . THR C 3 114 ? 58.069 40.062 95.492 1.00 13.82 ? 107 THR H CA 1 ATOM 5627 C C . THR C 3 114 ? 57.919 39.254 94.226 1.00 14.07 ? 107 THR H C 1 ATOM 5628 O O . THR C 3 114 ? 57.870 38.023 94.259 1.00 14.76 ? 107 THR H O 1 ATOM 5629 C CB . THR C 3 114 ? 59.585 40.206 95.915 1.00 10.80 ? 107 THR H CB 1 ATOM 5630 O OG1 . THR C 3 114 ? 59.605 41.032 97.071 1.00 10.07 ? 107 THR H OG1 1 ATOM 5631 C CG2 . THR C 3 114 ? 60.486 40.939 94.906 1.00 9.45 ? 107 THR H CG2 1 ATOM 5632 N N . THR C 3 115 ? 57.747 39.956 93.111 1.00 15.95 ? 108 THR H N 1 ATOM 5633 C CA . THR C 3 115 ? 57.439 39.263 91.872 1.00 18.43 ? 108 THR H CA 1 ATOM 5634 C C . THR C 3 115 ? 58.481 39.343 90.771 1.00 20.02 ? 108 THR H C 1 ATOM 5635 O O . THR C 3 115 ? 58.927 40.404 90.303 1.00 21.63 ? 108 THR H O 1 ATOM 5636 C CB . THR C 3 115 ? 56.117 39.813 91.409 1.00 16.79 ? 108 THR H CB 1 ATOM 5637 O OG1 . THR C 3 115 ? 55.309 39.857 92.605 1.00 17.29 ? 108 THR H OG1 1 ATOM 5638 C CG2 . THR C 3 115 ? 55.541 39.022 90.215 1.00 16.99 ? 108 THR H CG2 1 ATOM 5639 N N . LEU C 3 116 ? 58.858 38.143 90.395 1.00 21.58 ? 109 LEU H N 1 ATOM 5640 C CA . LEU C 3 116 ? 59.937 38.069 89.481 1.00 24.06 ? 109 LEU H CA 1 ATOM 5641 C C . LEU C 3 116 ? 59.337 37.715 88.150 1.00 24.99 ? 109 LEU H C 1 ATOM 5642 O O . LEU C 3 116 ? 58.733 36.664 87.924 1.00 24.04 ? 109 LEU H O 1 ATOM 5643 C CB . LEU C 3 116 ? 60.908 37.016 89.945 1.00 21.13 ? 109 LEU H CB 1 ATOM 5644 C CG . LEU C 3 116 ? 62.218 36.972 89.189 1.00 20.03 ? 109 LEU H CG 1 ATOM 5645 C CD1 . LEU C 3 116 ? 63.054 38.229 89.452 1.00 18.41 ? 109 LEU H CD1 1 ATOM 5646 C CD2 . LEU C 3 116 ? 62.962 35.732 89.646 1.00 19.77 ? 109 LEU H CD2 1 ATOM 5647 N N . THR C 3 117 ? 59.519 38.682 87.287 1.00 27.68 ? 110 THR H N 1 ATOM 5648 C CA . THR C 3 117 ? 59.146 38.527 85.912 1.00 31.23 ? 110 THR H CA 1 ATOM 5649 C C . THR C 3 117 ? 60.485 38.290 85.194 1.00 30.88 ? 110 THR H C 1 ATOM 5650 O O . THR C 3 117 ? 61.270 39.216 84.902 1.00 30.26 ? 110 THR H O 1 ATOM 5651 C CB . THR C 3 117 ? 58.431 39.819 85.515 1.00 31.58 ? 110 THR H CB 1 ATOM 5652 O OG1 . THR C 3 117 ? 57.646 40.199 86.653 1.00 33.58 ? 110 THR H OG1 1 ATOM 5653 C CG2 . THR C 3 117 ? 57.575 39.654 84.268 1.00 32.20 ? 110 THR H CG2 1 ATOM 5654 N N . VAL C 3 118 ? 60.798 37.005 84.987 1.00 28.91 ? 111 VAL H N 1 ATOM 5655 C CA . VAL C 3 118 ? 61.998 36.623 84.254 1.00 28.57 ? 111 VAL H CA 1 ATOM 5656 C C . VAL C 3 118 ? 61.577 36.803 82.812 1.00 28.29 ? 111 VAL H C 1 ATOM 5657 O O . VAL C 3 118 ? 60.593 36.199 82.364 1.00 28.83 ? 111 VAL H O 1 ATOM 5658 C CB . VAL C 3 118 ? 62.385 35.156 84.638 1.00 28.63 ? 111 VAL H CB 1 ATOM 5659 C CG1 . VAL C 3 118 ? 63.337 34.401 83.702 1.00 29.01 ? 111 VAL H CG1 1 ATOM 5660 C CG2 . VAL C 3 118 ? 63.177 35.342 85.926 1.00 28.99 ? 111 VAL H CG2 1 ATOM 5661 N N . SER C 3 119 ? 62.281 37.720 82.144 1.00 27.79 ? 112 SER H N 1 ATOM 5662 C CA . SER C 3 119 ? 61.932 38.110 80.797 1.00 28.05 ? 112 SER H CA 1 ATOM 5663 C C . SER C 3 119 ? 63.018 38.755 79.952 1.00 28.42 ? 112 SER H C 1 ATOM 5664 O O . SER C 3 119 ? 63.762 39.653 80.351 1.00 28.63 ? 112 SER H O 1 ATOM 5665 C CB . SER C 3 119 ? 60.741 39.085 80.823 1.00 29.39 ? 112 SER H CB 1 ATOM 5666 O OG . SER C 3 119 ? 59.913 38.989 79.653 1.00 31.50 ? 112 SER H OG 1 ATOM 5667 N N . SER C 3 120 ? 63.000 38.285 78.712 1.00 28.70 ? 113 SER H N 1 ATOM 5668 C CA . SER C 3 120 ? 63.842 38.801 77.640 1.00 29.01 ? 113 SER H CA 1 ATOM 5669 C C . SER C 3 120 ? 63.327 40.155 77.118 1.00 28.96 ? 113 SER H C 1 ATOM 5670 O O . SER C 3 120 ? 63.997 40.870 76.363 1.00 28.08 ? 113 SER H O 1 ATOM 5671 C CB . SER C 3 120 ? 63.851 37.809 76.459 1.00 29.02 ? 113 SER H CB 1 ATOM 5672 O OG . SER C 3 120 ? 63.930 36.418 76.817 1.00 29.28 ? 113 SER H OG 1 ATOM 5673 N N . ALA C 3 121 ? 62.073 40.472 77.445 1.00 27.35 ? 114 ALA H N 1 ATOM 5674 C CA . ALA C 3 121 ? 61.437 41.636 76.900 1.00 28.26 ? 114 ALA H CA 1 ATOM 5675 C C . ALA C 3 121 ? 62.029 42.938 77.406 1.00 30.43 ? 114 ALA H C 1 ATOM 5676 O O . ALA C 3 121 ? 62.735 42.954 78.422 1.00 31.37 ? 114 ALA H O 1 ATOM 5677 C CB . ALA C 3 121 ? 59.981 41.549 77.241 1.00 27.60 ? 114 ALA H CB 1 ATOM 5678 N N . LYS C 3 122 ? 61.752 44.022 76.662 1.00 31.66 ? 115 LYS H N 1 ATOM 5679 C CA . LYS C 3 122 ? 62.234 45.357 76.992 1.00 31.46 ? 115 LYS H CA 1 ATOM 5680 C C . LYS C 3 122 ? 61.131 46.190 77.672 1.00 32.44 ? 115 LYS H C 1 ATOM 5681 O O . LYS C 3 122 ? 59.917 45.998 77.458 1.00 31.47 ? 115 LYS H O 1 ATOM 5682 C CB . LYS C 3 122 ? 62.699 46.036 75.702 1.00 30.20 ? 115 LYS H CB 1 ATOM 5683 C CG . LYS C 3 122 ? 64.015 45.485 75.148 1.00 29.59 ? 115 LYS H CG 1 ATOM 5684 C CD . LYS C 3 122 ? 64.098 45.610 73.624 1.00 29.26 ? 115 LYS H CD 1 ATOM 5685 C CE . LYS C 3 122 ? 64.164 47.035 73.070 1.00 29.08 ? 115 LYS H CE 1 ATOM 5686 N NZ . LYS C 3 122 ? 65.473 47.638 73.243 1.00 28.91 ? 115 LYS H NZ 1 ATOM 5687 N N . THR C 3 123 ? 61.567 47.116 78.518 1.00 34.81 ? 116 THR H N 1 ATOM 5688 C CA . THR C 3 123 ? 60.683 48.059 79.183 1.00 35.96 ? 116 THR H CA 1 ATOM 5689 C C . THR C 3 123 ? 60.020 48.930 78.125 1.00 36.66 ? 116 THR H C 1 ATOM 5690 O O . THR C 3 123 ? 60.725 49.596 77.363 1.00 36.56 ? 116 THR H O 1 ATOM 5691 C CB . THR C 3 123 ? 61.466 49.001 80.140 1.00 37.39 ? 116 THR H CB 1 ATOM 5692 O OG1 . THR C 3 123 ? 62.166 48.167 81.071 1.00 39.75 ? 116 THR H OG1 1 ATOM 5693 C CG2 . THR C 3 123 ? 60.571 50.026 80.830 1.00 38.19 ? 116 THR H CG2 1 ATOM 5694 N N . THR C 3 124 ? 58.700 48.963 78.037 1.00 37.57 ? 117 THR H N 1 ATOM 5695 C CA . THR C 3 124 ? 58.070 49.901 77.137 1.00 36.38 ? 117 THR H CA 1 ATOM 5696 C C . THR C 3 124 ? 57.242 50.725 78.114 1.00 36.86 ? 117 THR H C 1 ATOM 5697 O O . THR C 3 124 ? 56.676 50.158 79.061 1.00 36.60 ? 117 THR H O 1 ATOM 5698 C CB . THR C 3 124 ? 57.195 49.154 76.113 1.00 37.17 ? 117 THR H CB 1 ATOM 5699 O OG1 . THR C 3 124 ? 58.012 48.281 75.319 1.00 38.23 ? 117 THR H OG1 1 ATOM 5700 C CG2 . THR C 3 124 ? 56.503 50.153 75.196 1.00 37.28 ? 117 THR H CG2 1 ATOM 5701 N N . ALA C 3 125 ? 57.224 52.049 77.951 1.00 35.37 ? 118 ALA H N 1 ATOM 5702 C CA . ALA C 3 125 ? 56.441 52.896 78.827 1.00 34.80 ? 118 ALA H CA 1 ATOM 5703 C C . ALA C 3 125 ? 55.061 53.106 78.195 1.00 33.58 ? 118 ALA H C 1 ATOM 5704 O O . ALA C 3 125 ? 55.011 53.048 76.967 1.00 33.13 ? 118 ALA H O 1 ATOM 5705 C CB . ALA C 3 125 ? 57.188 54.205 78.979 1.00 35.45 ? 118 ALA H CB 1 ATOM 5706 N N . PRO C 3 126 ? 53.944 53.333 78.927 1.00 34.11 ? 119 PRO H N 1 ATOM 5707 C CA . PRO C 3 126 ? 52.556 53.308 78.462 1.00 32.35 ? 119 PRO H CA 1 ATOM 5708 C C . PRO C 3 126 ? 51.966 54.550 77.782 1.00 31.61 ? 119 PRO H C 1 ATOM 5709 O O . PRO C 3 126 ? 52.419 55.705 77.887 1.00 31.66 ? 119 PRO H O 1 ATOM 5710 C CB . PRO C 3 126 ? 51.779 52.958 79.683 1.00 32.46 ? 119 PRO H CB 1 ATOM 5711 C CG . PRO C 3 126 ? 52.450 53.849 80.695 1.00 32.50 ? 119 PRO H CG 1 ATOM 5712 C CD . PRO C 3 126 ? 53.926 53.581 80.369 1.00 33.69 ? 119 PRO H CD 1 ATOM 5713 N N . SER C 3 127 ? 50.782 54.246 77.268 1.00 30.62 ? 120 SER H N 1 ATOM 5714 C CA . SER C 3 127 ? 49.936 55.139 76.537 1.00 29.66 ? 120 SER H CA 1 ATOM 5715 C C . SER C 3 127 ? 48.675 55.241 77.379 1.00 29.17 ? 120 SER H C 1 ATOM 5716 O O . SER C 3 127 ? 47.887 54.294 77.478 1.00 28.59 ? 120 SER H O 1 ATOM 5717 C CB . SER C 3 127 ? 49.664 54.528 75.182 1.00 29.62 ? 120 SER H CB 1 ATOM 5718 O OG . SER C 3 127 ? 50.691 54.891 74.267 1.00 31.39 ? 120 SER H OG 1 ATOM 5719 N N . VAL C 3 128 ? 48.533 56.372 78.058 1.00 26.48 ? 121 VAL H N 1 ATOM 5720 C CA . VAL C 3 128 ? 47.391 56.590 78.909 1.00 26.53 ? 121 VAL H CA 1 ATOM 5721 C C . VAL C 3 128 ? 46.370 57.308 78.003 1.00 28.20 ? 121 VAL H C 1 ATOM 5722 O O . VAL C 3 128 ? 46.725 58.309 77.362 1.00 27.07 ? 121 VAL H O 1 ATOM 5723 C CB . VAL C 3 128 ? 47.987 57.382 80.077 1.00 24.92 ? 121 VAL H CB 1 ATOM 5724 C CG1 . VAL C 3 128 ? 46.923 57.843 81.061 1.00 24.63 ? 121 VAL H CG1 1 ATOM 5725 C CG2 . VAL C 3 128 ? 48.995 56.477 80.775 1.00 22.72 ? 121 VAL H CG2 1 ATOM 5726 N N . TYR C 3 129 ? 45.137 56.789 77.844 1.00 28.44 ? 122 TYR H N 1 ATOM 5727 C CA . TYR C 3 129 ? 44.136 57.335 76.929 1.00 28.86 ? 122 TYR H CA 1 ATOM 5728 C C . TYR C 3 129 ? 42.809 57.563 77.601 1.00 28.27 ? 122 TYR H C 1 ATOM 5729 O O . TYR C 3 129 ? 42.201 56.598 78.073 1.00 28.35 ? 122 TYR H O 1 ATOM 5730 C CB . TYR C 3 129 ? 43.859 56.408 75.742 1.00 30.01 ? 122 TYR H CB 1 ATOM 5731 C CG . TYR C 3 129 ? 45.008 56.250 74.752 1.00 30.98 ? 122 TYR H CG 1 ATOM 5732 C CD1 . TYR C 3 129 ? 45.779 57.348 74.406 1.00 30.90 ? 122 TYR H CD1 1 ATOM 5733 C CD2 . TYR C 3 129 ? 45.272 55.021 74.185 1.00 31.40 ? 122 TYR H CD2 1 ATOM 5734 C CE1 . TYR C 3 129 ? 46.812 57.219 73.500 1.00 31.60 ? 122 TYR H CE1 1 ATOM 5735 C CE2 . TYR C 3 129 ? 46.298 54.899 73.274 1.00 31.43 ? 122 TYR H CE2 1 ATOM 5736 C CZ . TYR C 3 129 ? 47.069 55.995 72.928 1.00 31.50 ? 122 TYR H CZ 1 ATOM 5737 O OH . TYR C 3 129 ? 48.108 55.882 72.010 1.00 30.57 ? 122 TYR H OH 1 ATOM 5738 N N . PRO C 3 130 ? 42.336 58.816 77.670 1.00 28.91 ? 123 PRO H N 1 ATOM 5739 C CA . PRO C 3 130 ? 41.108 59.212 78.344 1.00 28.31 ? 123 PRO H CA 1 ATOM 5740 C C . PRO C 3 130 ? 39.949 58.740 77.497 1.00 28.20 ? 123 PRO H C 1 ATOM 5741 O O . PRO C 3 130 ? 39.939 58.971 76.284 1.00 28.85 ? 123 PRO H O 1 ATOM 5742 C CB . PRO C 3 130 ? 41.227 60.713 78.458 1.00 29.69 ? 123 PRO H CB 1 ATOM 5743 C CG . PRO C 3 130 ? 41.876 61.086 77.155 1.00 30.40 ? 123 PRO H CG 1 ATOM 5744 C CD . PRO C 3 130 ? 42.929 59.974 77.001 1.00 30.33 ? 123 PRO H CD 1 ATOM 5745 N N . LEU C 3 131 ? 38.984 58.054 78.083 1.00 27.27 ? 124 LEU H N 1 ATOM 5746 C CA . LEU C 3 131 ? 37.858 57.559 77.319 1.00 27.88 ? 124 LEU H CA 1 ATOM 5747 C C . LEU C 3 131 ? 36.636 58.272 77.852 1.00 27.58 ? 124 LEU H C 1 ATOM 5748 O O . LEU C 3 131 ? 36.096 57.944 78.914 1.00 27.33 ? 124 LEU H O 1 ATOM 5749 C CB . LEU C 3 131 ? 37.697 56.064 77.511 1.00 28.44 ? 124 LEU H CB 1 ATOM 5750 C CG . LEU C 3 131 ? 38.797 55.131 77.062 1.00 29.13 ? 124 LEU H CG 1 ATOM 5751 C CD1 . LEU C 3 131 ? 38.762 53.884 77.941 1.00 30.05 ? 124 LEU H CD1 1 ATOM 5752 C CD2 . LEU C 3 131 ? 38.637 54.840 75.576 1.00 30.37 ? 124 LEU H CD2 1 ATOM 5753 N N . ALA C 3 132 ? 36.237 59.335 77.185 1.00 28.41 ? 125 ALA H N 1 ATOM 5754 C CA . ALA C 3 132 ? 35.028 60.011 77.574 1.00 29.94 ? 125 ALA H CA 1 ATOM 5755 C C . ALA C 3 132 ? 33.967 59.272 76.775 1.00 32.15 ? 125 ALA H C 1 ATOM 5756 O O . ALA C 3 132 ? 34.277 58.679 75.731 1.00 31.54 ? 125 ALA H O 1 ATOM 5757 C CB . ALA C 3 132 ? 35.088 61.460 77.155 1.00 30.43 ? 125 ALA H CB 1 ATOM 5758 N N . PRO C 3 133 ? 32.716 59.237 77.228 1.00 34.20 ? 126 PRO H N 1 ATOM 5759 C CA . PRO C 3 133 ? 31.673 58.432 76.617 1.00 35.91 ? 126 PRO H CA 1 ATOM 5760 C C . PRO C 3 133 ? 31.149 59.059 75.314 1.00 38.11 ? 126 PRO H C 1 ATOM 5761 O O . PRO C 3 133 ? 31.241 60.270 75.067 1.00 39.28 ? 126 PRO H O 1 ATOM 5762 C CB . PRO C 3 133 ? 30.655 58.368 77.718 1.00 33.93 ? 126 PRO H CB 1 ATOM 5763 C CG . PRO C 3 133 ? 30.643 59.836 78.141 1.00 32.57 ? 126 PRO H CG 1 ATOM 5764 C CD . PRO C 3 133 ? 32.128 60.130 78.231 1.00 33.76 ? 126 PRO H CD 1 ATOM 5765 N N . VAL C 3 134 ? 30.487 58.272 74.482 1.00 40.17 ? 127 VAL H N 1 ATOM 5766 C CA . VAL C 3 134 ? 29.759 58.847 73.347 1.00 42.91 ? 127 VAL H CA 1 ATOM 5767 C C . VAL C 3 134 ? 28.361 59.180 73.948 1.00 43.40 ? 127 VAL H C 1 ATOM 5768 O O . VAL C 3 134 ? 27.288 58.746 73.509 1.00 45.24 ? 127 VAL H O 1 ATOM 5769 C CB . VAL C 3 134 ? 29.798 57.742 72.222 1.00 42.46 ? 127 VAL H CB 1 ATOM 5770 C CG1 . VAL C 3 134 ? 29.040 56.443 72.636 1.00 42.90 ? 127 VAL H CG1 1 ATOM 5771 C CG2 . VAL C 3 134 ? 29.292 58.402 70.931 1.00 43.59 ? 127 VAL H CG2 1 ATOM 5772 N N . CYS C 3 135 ? 28.411 60.032 74.984 1.00 43.30 ? 128 CYS H N 1 ATOM 5773 C CA . CYS C 3 135 ? 27.367 60.274 75.979 1.00 43.05 ? 128 CYS H CA 1 ATOM 5774 C C . CYS C 3 135 ? 26.779 58.962 76.483 1.00 42.86 ? 128 CYS H C 1 ATOM 5775 O O . CYS C 3 135 ? 27.499 58.354 77.273 1.00 42.81 ? 128 CYS H O 1 ATOM 5776 C CB . CYS C 3 135 ? 26.229 61.185 75.466 1.00 43.21 ? 128 CYS H CB 1 ATOM 5777 S SG . CYS C 3 135 ? 25.217 60.809 74.020 1.00 43.63 ? 128 CYS H SG 1 ATOM 5778 N N . GLY C 3 136 ? 25.610 58.426 76.122 1.00 42.83 ? 129 GLY H N 1 ATOM 5779 C CA . GLY C 3 136 ? 25.123 57.165 76.674 1.00 43.09 ? 129 GLY H CA 1 ATOM 5780 C C . GLY C 3 136 ? 24.950 57.163 78.193 1.00 43.42 ? 129 GLY H C 1 ATOM 5781 O O . GLY C 3 136 ? 25.825 56.711 78.939 1.00 43.39 ? 129 GLY H O 1 ATOM 5782 N N . ASP C 3 137 ? 23.790 57.652 78.650 1.00 43.97 ? 130 ASP H N 1 ATOM 5783 C CA . ASP C 3 137 ? 23.436 57.721 80.069 1.00 44.69 ? 130 ASP H CA 1 ATOM 5784 C C . ASP C 3 137 ? 23.589 56.339 80.690 1.00 45.04 ? 130 ASP H C 1 ATOM 5785 O O . ASP C 3 137 ? 22.767 55.433 80.507 1.00 45.37 ? 130 ASP H O 1 ATOM 5786 C CB . ASP C 3 137 ? 21.992 58.229 80.196 1.00 44.91 ? 130 ASP H CB 1 ATOM 5787 C CG . ASP C 3 137 ? 21.435 58.313 81.616 1.00 45.14 ? 130 ASP H CG 1 ATOM 5788 O OD1 . ASP C 3 137 ? 21.922 59.117 82.407 1.00 45.52 ? 130 ASP H OD1 1 ATOM 5789 O OD2 . ASP C 3 137 ? 20.507 57.563 81.927 1.00 45.10 ? 130 ASP H OD2 1 ATOM 5790 N N . THR C 3 138 ? 24.708 56.171 81.374 1.00 45.28 ? 133 THR H N 1 ATOM 5791 C CA . THR C 3 138 ? 25.070 54.895 81.927 1.00 45.37 ? 133 THR H CA 1 ATOM 5792 C C . THR C 3 138 ? 24.392 54.735 83.278 1.00 45.06 ? 133 THR H C 1 ATOM 5793 O O . THR C 3 138 ? 24.958 54.954 84.353 1.00 45.11 ? 133 THR H O 1 ATOM 5794 C CB . THR C 3 138 ? 26.613 54.826 82.008 1.00 45.70 ? 133 THR H CB 1 ATOM 5795 O OG1 . THR C 3 138 ? 27.244 55.984 81.435 1.00 45.84 ? 133 THR H OG1 1 ATOM 5796 C CG2 . THR C 3 138 ? 27.045 53.584 81.258 1.00 46.13 ? 133 THR H CG2 1 ATOM 5797 N N . THR C 3 139 ? 23.141 54.290 83.143 1.00 44.56 ? 134 THR H N 1 ATOM 5798 C CA . THR C 3 139 ? 22.149 54.077 84.196 1.00 43.98 ? 134 THR H CA 1 ATOM 5799 C C . THR C 3 139 ? 21.576 55.451 84.562 1.00 43.28 ? 134 THR H C 1 ATOM 5800 O O . THR C 3 139 ? 22.119 56.497 84.189 1.00 43.11 ? 134 THR H O 1 ATOM 5801 C CB . THR C 3 139 ? 22.759 53.395 85.469 1.00 44.30 ? 134 THR H CB 1 ATOM 5802 O OG1 . THR C 3 139 ? 23.723 52.448 85.016 1.00 44.48 ? 134 THR H OG1 1 ATOM 5803 C CG2 . THR C 3 139 ? 21.719 52.657 86.306 1.00 44.56 ? 134 THR H CG2 1 ATOM 5804 N N . GLY C 3 140 ? 20.423 55.485 85.237 1.00 42.45 ? 135 GLY H N 1 ATOM 5805 C CA . GLY C 3 140 ? 19.748 56.727 85.592 1.00 41.35 ? 135 GLY H CA 1 ATOM 5806 C C . GLY C 3 140 ? 20.646 57.689 86.358 1.00 40.51 ? 135 GLY H C 1 ATOM 5807 O O . GLY C 3 140 ? 21.173 57.351 87.416 1.00 40.30 ? 135 GLY H O 1 ATOM 5808 N N . SER C 3 141 ? 20.860 58.850 85.744 1.00 39.78 ? 136 SER H N 1 ATOM 5809 C CA . SER C 3 141 ? 21.660 59.940 86.283 1.00 39.15 ? 136 SER H CA 1 ATOM 5810 C C . SER C 3 141 ? 23.065 59.597 86.779 1.00 38.96 ? 136 SER H C 1 ATOM 5811 O O . SER C 3 141 ? 23.569 60.013 87.828 1.00 38.52 ? 136 SER H O 1 ATOM 5812 C CB . SER C 3 141 ? 20.814 60.597 87.369 1.00 38.92 ? 136 SER H CB 1 ATOM 5813 O OG . SER C 3 141 ? 19.668 61.145 86.715 1.00 38.81 ? 136 SER H OG 1 ATOM 5814 N N . SER C 3 142 ? 23.764 58.978 85.839 1.00 37.86 ? 137 SER H N 1 ATOM 5815 C CA . SER C 3 142 ? 25.112 58.462 86.013 1.00 38.65 ? 137 SER H CA 1 ATOM 5816 C C . SER C 3 142 ? 25.834 58.345 84.669 1.00 36.46 ? 137 SER H C 1 ATOM 5817 O O . SER C 3 142 ? 25.253 58.306 83.570 1.00 36.74 ? 137 SER H O 1 ATOM 5818 C CB . SER C 3 142 ? 25.051 57.088 86.715 1.00 42.10 ? 137 SER H CB 1 ATOM 5819 O OG . SER C 3 142 ? 24.909 57.181 88.148 1.00 45.33 ? 137 SER H OG 1 ATOM 5820 N N . VAL C 3 143 ? 27.147 58.408 84.764 1.00 32.07 ? 138 VAL H N 1 ATOM 5821 C CA . VAL C 3 143 ? 27.981 58.409 83.604 1.00 28.22 ? 138 VAL H CA 1 ATOM 5822 C C . VAL C 3 143 ? 29.208 57.636 84.013 1.00 27.34 ? 138 VAL H C 1 ATOM 5823 O O . VAL C 3 143 ? 29.724 57.841 85.110 1.00 29.06 ? 138 VAL H O 1 ATOM 5824 C CB . VAL C 3 143 ? 28.247 59.902 83.224 1.00 27.82 ? 138 VAL H CB 1 ATOM 5825 C CG1 . VAL C 3 143 ? 28.740 60.742 84.391 1.00 26.25 ? 138 VAL H CG1 1 ATOM 5826 C CG2 . VAL C 3 143 ? 29.298 59.923 82.116 1.00 28.81 ? 138 VAL H CG2 1 ATOM 5827 N N . THR C 3 144 ? 29.647 56.709 83.182 1.00 25.11 ? 139 THR H N 1 ATOM 5828 C CA . THR C 3 144 ? 30.841 55.974 83.473 1.00 23.86 ? 139 THR H CA 1 ATOM 5829 C C . THR C 3 144 ? 31.982 56.425 82.576 1.00 23.49 ? 139 THR H C 1 ATOM 5830 O O . THR C 3 144 ? 31.822 56.404 81.362 1.00 24.06 ? 139 THR H O 1 ATOM 5831 C CB . THR C 3 144 ? 30.521 54.531 83.270 1.00 25.09 ? 139 THR H CB 1 ATOM 5832 O OG1 . THR C 3 144 ? 29.339 54.212 84.030 1.00 25.62 ? 139 THR H OG1 1 ATOM 5833 C CG2 . THR C 3 144 ? 31.732 53.704 83.666 1.00 24.27 ? 139 THR H CG2 1 ATOM 5834 N N . LEU C 3 145 ? 33.118 56.892 83.072 1.00 24.26 ? 140 LEU H N 1 ATOM 5835 C CA . LEU C 3 145 ? 34.196 57.293 82.213 1.00 24.79 ? 140 LEU H CA 1 ATOM 5836 C C . LEU C 3 145 ? 35.386 56.354 82.395 1.00 23.86 ? 140 LEU H C 1 ATOM 5837 O O . LEU C 3 145 ? 35.461 55.642 83.404 1.00 24.13 ? 140 LEU H O 1 ATOM 5838 C CB . LEU C 3 145 ? 34.546 58.742 82.506 1.00 26.73 ? 140 LEU H CB 1 ATOM 5839 C CG . LEU C 3 145 ? 34.137 59.490 83.775 1.00 28.71 ? 140 LEU H CG 1 ATOM 5840 C CD1 . LEU C 3 145 ? 34.740 60.854 83.609 1.00 29.51 ? 140 LEU H CD1 1 ATOM 5841 C CD2 . LEU C 3 145 ? 32.639 59.709 83.967 1.00 29.03 ? 140 LEU H CD2 1 ATOM 5842 N N . GLY C 3 146 ? 36.314 56.309 81.433 1.00 22.94 ? 141 GLY H N 1 ATOM 5843 C CA . GLY C 3 146 ? 37.315 55.254 81.386 1.00 22.31 ? 141 GLY H CA 1 ATOM 5844 C C . GLY C 3 146 ? 38.733 55.661 81.022 1.00 22.20 ? 141 GLY H C 1 ATOM 5845 O O . GLY C 3 146 ? 38.973 56.734 80.471 1.00 24.62 ? 141 GLY H O 1 ATOM 5846 N N . CYS C 3 147 ? 39.694 54.804 81.308 1.00 22.45 ? 142 CYS H N 1 ATOM 5847 C CA . CYS C 3 147 ? 41.055 55.178 81.094 1.00 23.41 ? 142 CYS H CA 1 ATOM 5848 C C . CYS C 3 147 ? 41.742 53.917 80.687 1.00 24.27 ? 142 CYS H C 1 ATOM 5849 O O . CYS C 3 147 ? 41.715 52.941 81.438 1.00 24.39 ? 142 CYS H O 1 ATOM 5850 C CB . CYS C 3 147 ? 41.587 55.728 82.388 1.00 22.91 ? 142 CYS H CB 1 ATOM 5851 S SG . CYS C 3 147 ? 43.142 56.591 82.147 1.00 21.82 ? 142 CYS H SG 1 ATOM 5852 N N . LEU C 3 148 ? 42.165 53.923 79.424 1.00 24.99 ? 143 LEU H N 1 ATOM 5853 C CA . LEU C 3 148 ? 42.898 52.818 78.824 1.00 24.23 ? 143 LEU H CA 1 ATOM 5854 C C . LEU C 3 148 ? 44.396 53.124 78.888 1.00 23.80 ? 143 LEU H C 1 ATOM 5855 O O . LEU C 3 148 ? 44.949 54.099 78.348 1.00 23.84 ? 143 LEU H O 1 ATOM 5856 C CB . LEU C 3 148 ? 42.494 52.597 77.350 1.00 24.60 ? 143 LEU H CB 1 ATOM 5857 C CG . LEU C 3 148 ? 43.101 51.370 76.622 1.00 26.38 ? 143 LEU H CG 1 ATOM 5858 C CD1 . LEU C 3 148 ? 42.417 50.104 77.104 1.00 27.46 ? 143 LEU H CD1 1 ATOM 5859 C CD2 . LEU C 3 148 ? 42.850 51.437 75.121 1.00 25.47 ? 143 LEU H CD2 1 ATOM 5860 N N . VAL C 3 149 ? 45.065 52.277 79.641 1.00 23.07 ? 144 VAL H N 1 ATOM 5861 C CA . VAL C 3 149 ? 46.496 52.413 79.769 1.00 23.69 ? 144 VAL H CA 1 ATOM 5862 C C . VAL C 3 149 ? 47.136 51.301 78.931 1.00 22.98 ? 144 VAL H C 1 ATOM 5863 O O . VAL C 3 149 ? 47.276 50.168 79.392 1.00 23.75 ? 144 VAL H O 1 ATOM 5864 C CB . VAL C 3 149 ? 46.819 52.322 81.265 1.00 22.47 ? 144 VAL H CB 1 ATOM 5865 C CG1 . VAL C 3 149 ? 48.238 52.840 81.440 1.00 21.93 ? 144 VAL H CG1 1 ATOM 5866 C CG2 . VAL C 3 149 ? 45.803 53.093 82.117 1.00 21.54 ? 144 VAL H CG2 1 ATOM 5867 N N . LYS C 3 150 ? 47.449 51.574 77.665 1.00 23.79 ? 145 LYS H N 1 ATOM 5868 C CA . LYS C 3 150 ? 48.058 50.610 76.747 1.00 24.25 ? 145 LYS H CA 1 ATOM 5869 C C . LYS C 3 150 ? 49.588 50.680 76.583 1.00 23.95 ? 145 LYS H C 1 ATOM 5870 O O . LYS C 3 150 ? 50.246 51.670 76.916 1.00 23.49 ? 145 LYS H O 1 ATOM 5871 C CB . LYS C 3 150 ? 47.465 50.726 75.315 1.00 24.48 ? 145 LYS H CB 1 ATOM 5872 C CG . LYS C 3 150 ? 47.008 49.365 74.738 1.00 24.48 ? 145 LYS H CG 1 ATOM 5873 C CD . LYS C 3 150 ? 46.883 49.305 73.205 1.00 24.56 ? 145 LYS H CD 1 ATOM 5874 C CE . LYS C 3 150 ? 45.982 48.189 72.611 1.00 25.37 ? 145 LYS H CE 1 ATOM 5875 N NZ . LYS C 3 150 ? 46.308 46.804 72.955 1.00 27.35 ? 145 LYS H NZ 1 ATOM 5876 N N . GLY C 3 151 ? 50.124 49.538 76.132 1.00 24.14 ? 146 GLY H N 1 ATOM 5877 C CA . GLY C 3 151 ? 51.490 49.355 75.656 1.00 26.35 ? 146 GLY H CA 1 ATOM 5878 C C . GLY C 3 151 ? 52.647 49.580 76.611 1.00 26.99 ? 146 GLY H C 1 ATOM 5879 O O . GLY C 3 151 ? 53.487 50.455 76.381 1.00 29.17 ? 146 GLY H O 1 ATOM 5880 N N . TYR C 3 152 ? 52.774 48.777 77.649 1.00 26.28 ? 147 TYR H N 1 ATOM 5881 C CA . TYR C 3 152 ? 53.869 48.975 78.584 1.00 25.79 ? 147 TYR H CA 1 ATOM 5882 C C . TYR C 3 152 ? 54.356 47.606 78.967 1.00 23.78 ? 147 TYR H C 1 ATOM 5883 O O . TYR C 3 152 ? 53.620 46.599 78.820 1.00 22.38 ? 147 TYR H O 1 ATOM 5884 C CB . TYR C 3 152 ? 53.429 49.716 79.860 1.00 26.34 ? 147 TYR H CB 1 ATOM 5885 C CG . TYR C 3 152 ? 52.329 49.058 80.689 1.00 27.77 ? 147 TYR H CG 1 ATOM 5886 C CD1 . TYR C 3 152 ? 51.005 49.284 80.414 1.00 28.87 ? 147 TYR H CD1 1 ATOM 5887 C CD2 . TYR C 3 152 ? 52.690 48.200 81.696 1.00 29.32 ? 147 TYR H CD2 1 ATOM 5888 C CE1 . TYR C 3 152 ? 50.035 48.642 81.144 1.00 29.41 ? 147 TYR H CE1 1 ATOM 5889 C CE2 . TYR C 3 152 ? 51.730 47.552 82.422 1.00 29.52 ? 147 TYR H CE2 1 ATOM 5890 C CZ . TYR C 3 152 ? 50.406 47.778 82.144 1.00 30.75 ? 147 TYR H CZ 1 ATOM 5891 O OH . TYR C 3 152 ? 49.458 47.118 82.910 1.00 31.15 ? 147 TYR H OH 1 ATOM 5892 N N . PHE C 3 153 ? 55.576 47.643 79.496 1.00 22.50 ? 148 PHE H N 1 ATOM 5893 C CA . PHE C 3 153 ? 56.212 46.451 80.011 1.00 22.15 ? 148 PHE H CA 1 ATOM 5894 C C . PHE C 3 153 ? 57.278 46.975 80.953 1.00 21.57 ? 148 PHE H C 1 ATOM 5895 O O . PHE C 3 153 ? 57.938 47.954 80.582 1.00 21.78 ? 148 PHE H O 1 ATOM 5896 C CB . PHE C 3 153 ? 56.889 45.647 78.903 1.00 21.50 ? 148 PHE H CB 1 ATOM 5897 C CG . PHE C 3 153 ? 57.248 44.246 79.368 1.00 19.92 ? 148 PHE H CG 1 ATOM 5898 C CD1 . PHE C 3 153 ? 56.276 43.265 79.382 1.00 19.63 ? 148 PHE H CD1 1 ATOM 5899 C CD2 . PHE C 3 153 ? 58.538 43.967 79.789 1.00 20.27 ? 148 PHE H CD2 1 ATOM 5900 C CE1 . PHE C 3 153 ? 56.577 41.988 79.813 1.00 19.98 ? 148 PHE H CE1 1 ATOM 5901 C CE2 . PHE C 3 153 ? 58.830 42.690 80.217 1.00 20.38 ? 148 PHE H CE2 1 ATOM 5902 C CZ . PHE C 3 153 ? 57.851 41.709 80.230 1.00 20.38 ? 148 PHE H CZ 1 ATOM 5903 N N . PRO C 3 154 ? 57.500 46.361 82.137 1.00 22.50 ? 149 PRO H N 1 ATOM 5904 C CA . PRO C 3 154 ? 56.765 45.194 82.681 1.00 23.56 ? 149 PRO H CA 1 ATOM 5905 C C . PRO C 3 154 ? 55.545 45.559 83.552 1.00 26.77 ? 149 PRO H C 1 ATOM 5906 O O . PRO C 3 154 ? 55.160 46.735 83.537 1.00 28.27 ? 149 PRO H O 1 ATOM 5907 C CB . PRO C 3 154 ? 57.857 44.469 83.419 1.00 21.19 ? 149 PRO H CB 1 ATOM 5908 C CG . PRO C 3 154 ? 58.566 45.618 84.098 1.00 20.61 ? 149 PRO H CG 1 ATOM 5909 C CD . PRO C 3 154 ? 58.534 46.770 83.082 1.00 20.32 ? 149 PRO H CD 1 ATOM 5910 N N . GLU C 3 155 ? 54.897 44.634 84.287 1.00 30.01 ? 150 GLU H N 1 ATOM 5911 C CA . GLU C 3 155 ? 53.792 44.977 85.190 1.00 33.89 ? 150 GLU H CA 1 ATOM 5912 C C . GLU C 3 155 ? 54.499 45.347 86.486 1.00 31.65 ? 150 GLU H C 1 ATOM 5913 O O . GLU C 3 155 ? 55.450 44.605 86.752 1.00 31.32 ? 150 GLU H O 1 ATOM 5914 C CB . GLU C 3 155 ? 52.906 43.771 85.435 1.00 38.32 ? 150 GLU H CB 1 ATOM 5915 C CG . GLU C 3 155 ? 51.461 43.909 84.991 1.00 44.72 ? 150 GLU H CG 1 ATOM 5916 C CD . GLU C 3 155 ? 50.589 44.883 85.773 1.00 48.55 ? 150 GLU H CD 1 ATOM 5917 O OE1 . GLU C 3 155 ? 50.747 46.094 85.611 1.00 51.51 ? 150 GLU H OE1 1 ATOM 5918 O OE2 . GLU C 3 155 ? 49.736 44.415 86.526 1.00 50.30 ? 150 GLU H OE2 1 ATOM 5919 N N . PRO C 3 156 ? 54.193 46.322 87.368 1.00 31.53 ? 151 PRO H N 1 ATOM 5920 C CA . PRO C 3 156 ? 52.948 47.055 87.558 1.00 31.36 ? 151 PRO H CA 1 ATOM 5921 C C . PRO C 3 156 ? 52.707 48.415 86.889 1.00 31.62 ? 151 PRO H C 1 ATOM 5922 O O . PRO C 3 156 ? 53.553 48.950 86.172 1.00 34.22 ? 151 PRO H O 1 ATOM 5923 C CB . PRO C 3 156 ? 52.849 47.132 89.077 1.00 31.98 ? 151 PRO H CB 1 ATOM 5924 C CG . PRO C 3 156 ? 54.212 46.756 89.601 1.00 30.99 ? 151 PRO H CG 1 ATOM 5925 C CD . PRO C 3 156 ? 55.099 46.839 88.373 1.00 31.36 ? 151 PRO H CD 1 ATOM 5926 N N . VAL C 3 157 ? 51.533 48.992 87.196 1.00 31.39 ? 152 VAL H N 1 ATOM 5927 C CA . VAL C 3 157 ? 51.084 50.324 86.783 1.00 30.66 ? 152 VAL H CA 1 ATOM 5928 C C . VAL C 3 157 ? 50.212 50.845 87.943 1.00 28.75 ? 152 VAL H C 1 ATOM 5929 O O . VAL C 3 157 ? 49.393 50.072 88.454 1.00 29.64 ? 152 VAL H O 1 ATOM 5930 C CB . VAL C 3 157 ? 50.276 50.193 85.454 1.00 30.80 ? 152 VAL H CB 1 ATOM 5931 C CG1 . VAL C 3 157 ? 49.422 51.404 85.157 1.00 30.34 ? 152 VAL H CG1 1 ATOM 5932 C CG2 . VAL C 3 157 ? 51.231 50.268 84.297 1.00 32.30 ? 152 VAL H CG2 1 ATOM 5933 N N . THR C 3 158 ? 50.335 52.072 88.449 1.00 27.94 ? 153 THR H N 1 ATOM 5934 C CA . THR C 3 158 ? 49.470 52.549 89.532 1.00 26.98 ? 153 THR H CA 1 ATOM 5935 C C . THR C 3 158 ? 48.464 53.483 88.861 1.00 26.47 ? 153 THR H C 1 ATOM 5936 O O . THR C 3 158 ? 48.802 54.376 88.071 1.00 28.70 ? 153 THR H O 1 ATOM 5937 C CB . THR C 3 158 ? 50.359 53.274 90.626 1.00 25.34 ? 153 THR H CB 1 ATOM 5938 O OG1 . THR C 3 158 ? 51.272 52.271 91.103 1.00 25.65 ? 153 THR H OG1 1 ATOM 5939 C CG2 . THR C 3 158 ? 49.584 53.855 91.802 1.00 24.11 ? 153 THR H CG2 1 ATOM 5940 N N . LEU C 3 159 ? 47.191 53.253 89.125 1.00 24.64 ? 154 LEU H N 1 ATOM 5941 C CA . LEU C 3 159 ? 46.165 54.052 88.496 1.00 25.37 ? 154 LEU H CA 1 ATOM 5942 C C . LEU C 3 159 ? 45.295 54.612 89.611 1.00 26.85 ? 154 LEU H C 1 ATOM 5943 O O . LEU C 3 159 ? 44.882 53.875 90.520 1.00 27.96 ? 154 LEU H O 1 ATOM 5944 C CB . LEU C 3 159 ? 45.366 53.170 87.561 1.00 23.45 ? 154 LEU H CB 1 ATOM 5945 C CG . LEU C 3 159 ? 44.791 53.839 86.321 1.00 23.51 ? 154 LEU H CG 1 ATOM 5946 C CD1 . LEU C 3 159 ? 44.339 52.731 85.433 1.00 22.50 ? 154 LEU H CD1 1 ATOM 5947 C CD2 . LEU C 3 159 ? 43.602 54.754 86.599 1.00 24.06 ? 154 LEU H CD2 1 ATOM 5948 N N . THR C 3 160 ? 45.055 55.931 89.615 1.00 27.58 ? 156 THR H N 1 ATOM 5949 C CA . THR C 3 160 ? 44.233 56.596 90.628 1.00 27.18 ? 156 THR H CA 1 ATOM 5950 C C . THR C 3 160 ? 43.347 57.651 89.959 1.00 28.53 ? 156 THR H C 1 ATOM 5951 O O . THR C 3 160 ? 43.883 58.569 89.320 1.00 28.44 ? 156 THR H O 1 ATOM 5952 C CB . THR C 3 160 ? 45.148 57.257 91.675 1.00 27.67 ? 156 THR H CB 1 ATOM 5953 O OG1 . THR C 3 160 ? 46.201 57.940 91.007 1.00 28.98 ? 156 THR H OG1 1 ATOM 5954 C CG2 . THR C 3 160 ? 45.773 56.237 92.586 1.00 27.71 ? 156 THR H CG2 1 ATOM 5955 N N . TRP C 3 161 ? 42.013 57.548 90.023 1.00 27.87 ? 157 TRP H N 1 ATOM 5956 C CA . TRP C 3 161 ? 41.158 58.514 89.360 1.00 27.88 ? 157 TRP H CA 1 ATOM 5957 C C . TRP C 3 161 ? 41.145 59.674 90.293 1.00 27.78 ? 157 TRP H C 1 ATOM 5958 O O . TRP C 3 161 ? 40.464 59.650 91.315 1.00 27.87 ? 157 TRP H O 1 ATOM 5959 C CB . TRP C 3 161 ? 39.755 58.027 89.201 1.00 29.58 ? 157 TRP H CB 1 ATOM 5960 C CG . TRP C 3 161 ? 39.600 57.023 88.077 1.00 31.28 ? 157 TRP H CG 1 ATOM 5961 C CD1 . TRP C 3 161 ? 39.625 55.680 88.315 1.00 31.27 ? 157 TRP H CD1 1 ATOM 5962 C CD2 . TRP C 3 161 ? 39.367 57.323 86.763 1.00 30.55 ? 157 TRP H CD2 1 ATOM 5963 N NE1 . TRP C 3 161 ? 39.385 55.118 87.158 1.00 30.25 ? 157 TRP H NE1 1 ATOM 5964 C CE2 . TRP C 3 161 ? 39.234 56.054 86.210 1.00 30.64 ? 157 TRP H CE2 1 ATOM 5965 C CE3 . TRP C 3 161 ? 39.251 58.453 85.987 1.00 30.79 ? 157 TRP H CE3 1 ATOM 5966 C CZ2 . TRP C 3 161 ? 38.961 55.884 84.867 1.00 30.63 ? 157 TRP H CZ2 1 ATOM 5967 C CZ3 . TRP C 3 161 ? 38.977 58.288 84.640 1.00 31.44 ? 157 TRP H CZ3 1 ATOM 5968 C CH2 . TRP C 3 161 ? 38.842 57.023 84.083 1.00 31.57 ? 157 TRP H CH2 1 ATOM 5969 N N . ASN C 3 162 ? 42.018 60.608 89.950 1.00 27.73 ? 162 ASN H N 1 ATOM 5970 C CA . ASN C 3 162 ? 42.245 61.822 90.699 1.00 30.13 ? 162 ASN H CA 1 ATOM 5971 C C . ASN C 3 162 ? 42.912 61.404 91.987 1.00 32.04 ? 162 ASN H C 1 ATOM 5972 O O . ASN C 3 162 ? 42.264 60.822 92.860 1.00 32.96 ? 162 ASN H O 1 ATOM 5973 C CB . ASN C 3 162 ? 40.962 62.592 91.110 1.00 29.73 ? 162 ASN H CB 1 ATOM 5974 C CG . ASN C 3 162 ? 40.247 63.428 90.065 1.00 29.46 ? 162 ASN H CG 1 ATOM 5975 O OD1 . ASN C 3 162 ? 39.059 63.695 90.185 1.00 28.72 ? 162 ASN H OD1 1 ATOM 5976 N ND2 . ASN C 3 162 ? 40.884 63.939 89.025 1.00 28.83 ? 162 ASN H ND2 1 ATOM 5977 N N . SER C 3 163 ? 44.226 61.586 92.064 1.00 31.68 ? 163 SER H N 1 ATOM 5978 C CA . SER C 3 163 ? 45.025 61.442 93.284 1.00 32.14 ? 163 SER H CA 1 ATOM 5979 C C . SER C 3 163 ? 44.494 60.573 94.442 1.00 32.05 ? 163 SER H C 1 ATOM 5980 O O . SER C 3 163 ? 44.508 60.982 95.597 1.00 32.96 ? 163 SER H O 1 ATOM 5981 C CB . SER C 3 163 ? 45.283 62.889 93.735 1.00 32.34 ? 163 SER H CB 1 ATOM 5982 O OG . SER C 3 163 ? 45.754 63.753 92.684 1.00 32.89 ? 163 SER H OG 1 ATOM 5983 N N . GLY C 3 164 ? 43.954 59.378 94.206 1.00 32.55 ? 164 GLY H N 1 ATOM 5984 C CA . GLY C 3 164 ? 43.336 58.592 95.267 1.00 32.78 ? 164 GLY H CA 1 ATOM 5985 C C . GLY C 3 164 ? 41.874 58.997 95.533 1.00 32.25 ? 164 GLY H C 1 ATOM 5986 O O . GLY C 3 164 ? 41.122 58.142 95.997 1.00 32.62 ? 164 GLY H O 1 ATOM 5987 N N . SER C 3 165 ? 41.419 60.226 95.259 1.00 31.78 ? 165 SER H N 1 ATOM 5988 C CA . SER C 3 165 ? 40.059 60.688 95.490 1.00 31.22 ? 165 SER H CA 1 ATOM 5989 C C . SER C 3 165 ? 38.840 60.029 94.859 1.00 30.70 ? 165 SER H C 1 ATOM 5990 O O . SER C 3 165 ? 37.826 59.903 95.553 1.00 33.46 ? 165 SER H O 1 ATOM 5991 C CB . SER C 3 165 ? 40.002 62.147 95.139 1.00 30.39 ? 165 SER H CB 1 ATOM 5992 O OG . SER C 3 165 ? 40.982 62.815 95.926 1.00 31.71 ? 165 SER H OG 1 ATOM 5993 N N . LEU C 3 166 ? 38.737 59.669 93.584 1.00 28.83 ? 166 LEU H N 1 ATOM 5994 C CA . LEU C 3 166 ? 37.577 58.908 93.163 1.00 28.34 ? 166 LEU H CA 1 ATOM 5995 C C . LEU C 3 166 ? 38.019 57.503 93.554 1.00 29.47 ? 166 LEU H C 1 ATOM 5996 O O . LEU C 3 166 ? 38.967 56.896 93.029 1.00 29.63 ? 166 LEU H O 1 ATOM 5997 C CB . LEU C 3 166 ? 37.339 59.074 91.644 1.00 27.97 ? 166 LEU H CB 1 ATOM 5998 C CG . LEU C 3 166 ? 36.134 59.926 91.219 1.00 27.27 ? 166 LEU H CG 1 ATOM 5999 C CD1 . LEU C 3 166 ? 36.175 61.269 91.904 1.00 26.34 ? 166 LEU H CD1 1 ATOM 6000 C CD2 . LEU C 3 166 ? 36.168 60.187 89.733 1.00 25.41 ? 166 LEU H CD2 1 ATOM 6001 N N . SER C 3 167 ? 37.367 57.107 94.643 1.00 31.09 ? 167 SER H N 1 ATOM 6002 C CA . SER C 3 167 ? 37.616 55.826 95.276 1.00 32.57 ? 167 SER H CA 1 ATOM 6003 C C . SER C 3 167 ? 36.441 54.855 95.114 1.00 32.12 ? 167 SER H C 1 ATOM 6004 O O . SER C 3 167 ? 36.655 53.668 94.850 1.00 31.58 ? 167 SER H O 1 ATOM 6005 C CB . SER C 3 167 ? 37.931 56.076 96.766 1.00 32.96 ? 167 SER H CB 1 ATOM 6006 O OG . SER C 3 167 ? 38.921 57.069 97.085 1.00 35.11 ? 167 SER H OG 1 ATOM 6007 N N . SER C 3 168 ? 35.179 55.298 95.235 1.00 32.78 ? 168 SER H N 1 ATOM 6008 C CA . SER C 3 168 ? 34.015 54.405 95.133 1.00 32.42 ? 168 SER H CA 1 ATOM 6009 C C . SER C 3 168 ? 33.478 54.463 93.724 1.00 31.09 ? 168 SER H C 1 ATOM 6010 O O . SER C 3 168 ? 33.257 55.553 93.172 1.00 29.43 ? 168 SER H O 1 ATOM 6011 C CB . SER C 3 168 ? 32.865 54.814 96.072 1.00 36.53 ? 168 SER H CB 1 ATOM 6012 O OG . SER C 3 168 ? 33.308 55.701 97.100 1.00 39.45 ? 168 SER H OG 1 ATOM 6013 N N . GLY C 3 169 ? 33.301 53.252 93.193 1.00 28.22 ? 169 GLY H N 1 ATOM 6014 C CA . GLY C 3 169 ? 32.801 53.083 91.824 1.00 26.09 ? 169 GLY H CA 1 ATOM 6015 C C . GLY C 3 169 ? 33.882 53.093 90.714 1.00 23.26 ? 169 GLY H C 1 ATOM 6016 O O . GLY C 3 169 ? 33.650 53.418 89.532 1.00 20.82 ? 169 GLY H O 1 ATOM 6017 N N . VAL C 3 170 ? 35.071 52.677 91.155 1.00 22.25 ? 171 VAL H N 1 ATOM 6018 C CA . VAL C 3 170 ? 36.222 52.551 90.299 1.00 21.69 ? 171 VAL H CA 1 ATOM 6019 C C . VAL C 3 170 ? 36.328 51.058 89.990 1.00 21.71 ? 171 VAL H C 1 ATOM 6020 O O . VAL C 3 170 ? 35.965 50.259 90.855 1.00 23.88 ? 171 VAL H O 1 ATOM 6021 C CB . VAL C 3 170 ? 37.408 53.087 91.075 1.00 20.51 ? 171 VAL H CB 1 ATOM 6022 C CG1 . VAL C 3 170 ? 38.703 52.913 90.311 1.00 20.45 ? 171 VAL H CG1 1 ATOM 6023 C CG2 . VAL C 3 170 ? 37.142 54.556 91.343 1.00 20.35 ? 171 VAL H CG2 1 ATOM 6024 N N . HIS C 3 171 ? 36.718 50.592 88.809 1.00 21.24 ? 172 HIS H N 1 ATOM 6025 C CA . HIS C 3 171 ? 36.975 49.182 88.552 1.00 20.43 ? 172 HIS H CA 1 ATOM 6026 C C . HIS C 3 171 ? 38.245 49.256 87.778 1.00 19.27 ? 172 HIS H C 1 ATOM 6027 O O . HIS C 3 171 ? 38.240 49.737 86.643 1.00 19.75 ? 172 HIS H O 1 ATOM 6028 C CB . HIS C 3 171 ? 35.997 48.531 87.647 1.00 23.33 ? 172 HIS H CB 1 ATOM 6029 C CG . HIS C 3 171 ? 34.721 48.098 88.313 1.00 28.07 ? 172 HIS H CG 1 ATOM 6030 N ND1 . HIS C 3 171 ? 34.508 46.902 88.846 1.00 28.61 ? 172 HIS H ND1 1 ATOM 6031 C CD2 . HIS C 3 171 ? 33.570 48.848 88.453 1.00 30.11 ? 172 HIS H CD2 1 ATOM 6032 C CE1 . HIS C 3 171 ? 33.269 46.895 89.309 1.00 29.47 ? 172 HIS H CE1 1 ATOM 6033 N NE2 . HIS C 3 171 ? 32.710 48.066 89.068 1.00 29.64 ? 172 HIS H NE2 1 ATOM 6034 N N . THR C 3 172 ? 39.361 49.008 88.405 1.00 17.03 ? 173 THR H N 1 ATOM 6035 C CA . THR C 3 172 ? 40.598 48.843 87.656 1.00 15.42 ? 173 THR H CA 1 ATOM 6036 C C . THR C 3 172 ? 40.572 47.335 87.379 1.00 14.60 ? 173 THR H C 1 ATOM 6037 O O . THR C 3 172 ? 40.217 46.544 88.261 1.00 15.75 ? 173 THR H O 1 ATOM 6038 C CB . THR C 3 172 ? 41.772 49.300 88.554 1.00 15.27 ? 173 THR H CB 1 ATOM 6039 O OG1 . THR C 3 172 ? 41.529 50.671 88.901 1.00 17.13 ? 173 THR H OG1 1 ATOM 6040 C CG2 . THR C 3 172 ? 43.117 49.144 87.885 1.00 17.02 ? 173 THR H CG2 1 ATOM 6041 N N . PHE C 3 173 ? 40.780 46.948 86.118 1.00 13.02 ? 174 PHE H N 1 ATOM 6042 C CA . PHE C 3 173 ? 40.776 45.557 85.644 1.00 9.74 ? 174 PHE H CA 1 ATOM 6043 C C . PHE C 3 173 ? 42.194 45.030 85.645 1.00 10.79 ? 174 PHE H C 1 ATOM 6044 O O . PHE C 3 173 ? 43.150 45.811 85.435 1.00 12.32 ? 174 PHE H O 1 ATOM 6045 C CB . PHE C 3 173 ? 40.269 45.453 84.212 1.00 6.94 ? 174 PHE H CB 1 ATOM 6046 C CG . PHE C 3 173 ? 38.817 45.844 84.134 1.00 6.37 ? 174 PHE H CG 1 ATOM 6047 C CD1 . PHE C 3 173 ? 37.879 44.872 84.357 1.00 5.28 ? 174 PHE H CD1 1 ATOM 6048 C CD2 . PHE C 3 173 ? 38.461 47.181 83.950 1.00 5.94 ? 174 PHE H CD2 1 ATOM 6049 C CE1 . PHE C 3 173 ? 36.562 45.263 84.382 1.00 3.72 ? 174 PHE H CE1 1 ATOM 6050 C CE2 . PHE C 3 173 ? 37.134 47.548 83.967 1.00 4.26 ? 174 PHE H CE2 1 ATOM 6051 C CZ . PHE C 3 173 ? 36.191 46.589 84.203 1.00 4.17 ? 174 PHE H CZ 1 ATOM 6052 N N . PRO C 3 174 ? 42.400 43.732 85.825 1.00 9.86 ? 175 PRO H N 1 ATOM 6053 C CA . PRO C 3 174 ? 43.711 43.135 85.728 1.00 10.98 ? 175 PRO H CA 1 ATOM 6054 C C . PRO C 3 174 ? 44.284 43.360 84.333 1.00 13.24 ? 175 PRO H C 1 ATOM 6055 O O . PRO C 3 174 ? 43.541 43.431 83.330 1.00 12.09 ? 175 PRO H O 1 ATOM 6056 C CB . PRO C 3 174 ? 43.489 41.726 85.993 1.00 9.56 ? 175 PRO H CB 1 ATOM 6057 C CG . PRO C 3 174 ? 42.156 41.683 86.656 1.00 9.29 ? 175 PRO H CG 1 ATOM 6058 C CD . PRO C 3 174 ? 41.370 42.726 85.926 1.00 8.54 ? 175 PRO H CD 1 ATOM 6059 N N . ALA C 3 175 ? 45.612 43.497 84.298 1.00 16.73 ? 176 ALA H N 1 ATOM 6060 C CA . ALA C 3 175 ? 46.291 43.705 83.028 1.00 19.51 ? 176 ALA H CA 1 ATOM 6061 C C . ALA C 3 175 ? 46.364 42.389 82.270 1.00 20.55 ? 176 ALA H C 1 ATOM 6062 O O . ALA C 3 175 ? 46.290 41.331 82.901 1.00 19.90 ? 176 ALA H O 1 ATOM 6063 C CB . ALA C 3 175 ? 47.712 44.234 83.261 1.00 20.04 ? 176 ALA H CB 1 ATOM 6064 N N . VAL C 3 176 ? 46.477 42.392 80.945 1.00 23.34 ? 177 VAL H N 1 ATOM 6065 C CA . VAL C 3 176 ? 46.644 41.178 80.161 1.00 25.04 ? 177 VAL H CA 1 ATOM 6066 C C . VAL C 3 176 ? 47.772 41.500 79.195 1.00 27.99 ? 177 VAL H C 1 ATOM 6067 O O . VAL C 3 176 ? 47.936 42.632 78.715 1.00 30.09 ? 177 VAL H O 1 ATOM 6068 C CB . VAL C 3 176 ? 45.314 40.812 79.419 1.00 24.60 ? 177 VAL H CB 1 ATOM 6069 C CG1 . VAL C 3 176 ? 44.763 41.987 78.660 1.00 25.70 ? 177 VAL H CG1 1 ATOM 6070 C CG2 . VAL C 3 176 ? 45.566 39.713 78.414 1.00 24.22 ? 177 VAL H CG2 1 ATOM 6071 N N . LEU C 3 177 ? 48.633 40.502 79.023 1.00 28.36 ? 178 LEU H N 1 ATOM 6072 C CA . LEU C 3 177 ? 49.794 40.546 78.137 1.00 28.31 ? 178 LEU H CA 1 ATOM 6073 C C . LEU C 3 177 ? 49.517 40.036 76.739 1.00 29.90 ? 178 LEU H C 1 ATOM 6074 O O . LEU C 3 177 ? 49.029 38.905 76.580 1.00 30.12 ? 178 LEU H O 1 ATOM 6075 C CB . LEU C 3 177 ? 50.886 39.700 78.723 1.00 27.34 ? 178 LEU H CB 1 ATOM 6076 C CG . LEU C 3 177 ? 52.190 39.577 78.028 1.00 26.77 ? 178 LEU H CG 1 ATOM 6077 C CD1 . LEU C 3 177 ? 53.093 40.764 78.266 1.00 26.59 ? 178 LEU H CD1 1 ATOM 6078 C CD2 . LEU C 3 177 ? 52.768 38.292 78.542 1.00 26.56 ? 178 LEU H CD2 1 ATOM 6079 N N . GLN C 3 178 ? 49.828 40.829 75.719 1.00 32.11 ? 179 GLN H N 1 ATOM 6080 C CA . GLN C 3 178 ? 49.667 40.374 74.362 1.00 34.92 ? 179 GLN H CA 1 ATOM 6081 C C . GLN C 3 178 ? 51.059 40.270 73.790 1.00 34.13 ? 179 GLN H C 1 ATOM 6082 O O . GLN C 3 178 ? 51.674 41.200 73.236 1.00 35.21 ? 179 GLN H O 1 ATOM 6083 C CB . GLN C 3 178 ? 48.866 41.363 73.619 1.00 41.12 ? 179 GLN H CB 1 ATOM 6084 C CG . GLN C 3 178 ? 47.897 40.573 72.786 1.00 47.23 ? 179 GLN H CG 1 ATOM 6085 C CD . GLN C 3 178 ? 47.105 41.506 71.884 1.00 51.10 ? 179 GLN H CD 1 ATOM 6086 O OE1 . GLN C 3 178 ? 46.878 42.704 72.149 1.00 52.44 ? 179 GLN H OE1 1 ATOM 6087 N NE2 . GLN C 3 178 ? 46.697 40.915 70.765 1.00 53.71 ? 179 GLN H NE2 1 ATOM 6088 N N . SER C 3 179 ? 51.553 39.077 74.111 1.00 31.04 ? 180 SER H N 1 ATOM 6089 C CA . SER C 3 179 ? 52.882 38.606 73.789 1.00 28.82 ? 180 SER H CA 1 ATOM 6090 C C . SER C 3 179 ? 53.894 39.557 74.398 1.00 28.47 ? 180 SER H C 1 ATOM 6091 O O . SER C 3 179 ? 54.330 39.272 75.514 1.00 27.51 ? 180 SER H O 1 ATOM 6092 C CB . SER C 3 179 ? 53.052 38.509 72.269 1.00 27.69 ? 180 SER H CB 1 ATOM 6093 O OG . SER C 3 179 ? 52.080 37.608 71.759 1.00 26.79 ? 180 SER H OG 1 ATOM 6094 N N . ASP C 3 180 ? 54.187 40.724 73.824 1.00 28.34 ? 183 ASP H N 1 ATOM 6095 C CA . ASP C 3 180 ? 55.233 41.521 74.403 1.00 29.45 ? 183 ASP H CA 1 ATOM 6096 C C . ASP C 3 180 ? 54.775 42.586 75.379 1.00 30.27 ? 183 ASP H C 1 ATOM 6097 O O . ASP C 3 180 ? 55.624 42.995 76.182 1.00 30.55 ? 183 ASP H O 1 ATOM 6098 C CB . ASP C 3 180 ? 56.055 42.160 73.272 1.00 27.96 ? 183 ASP H CB 1 ATOM 6099 C CG . ASP C 3 180 ? 57.449 42.585 73.733 1.00 26.91 ? 183 ASP H CG 1 ATOM 6100 O OD1 . ASP C 3 180 ? 58.273 41.715 74.018 1.00 26.22 ? 183 ASP H OD1 1 ATOM 6101 O OD2 . ASP C 3 180 ? 57.705 43.786 73.817 1.00 26.13 ? 183 ASP H OD2 1 ATOM 6102 N N . LEU C 3 181 ? 53.509 43.074 75.376 1.00 30.42 ? 184 LEU H N 1 ATOM 6103 C CA . LEU C 3 181 ? 53.141 44.163 76.298 1.00 29.29 ? 184 LEU H CA 1 ATOM 6104 C C . LEU C 3 181 ? 51.772 43.983 76.922 1.00 27.44 ? 184 LEU H C 1 ATOM 6105 O O . LEU C 3 181 ? 51.028 43.075 76.534 1.00 26.88 ? 184 LEU H O 1 ATOM 6106 C CB . LEU C 3 181 ? 53.183 45.516 75.561 1.00 30.71 ? 184 LEU H CB 1 ATOM 6107 C CG . LEU C 3 181 ? 54.354 45.794 74.595 1.00 30.37 ? 184 LEU H CG 1 ATOM 6108 C CD1 . LEU C 3 181 ? 53.942 45.383 73.198 1.00 31.94 ? 184 LEU H CD1 1 ATOM 6109 C CD2 . LEU C 3 181 ? 54.695 47.253 74.553 1.00 30.05 ? 184 LEU H CD2 1 ATOM 6110 N N . TYR C 3 182 ? 51.455 44.796 77.934 1.00 27.32 ? 185 TYR H N 1 ATOM 6111 C CA . TYR C 3 182 ? 50.161 44.693 78.604 1.00 26.41 ? 185 TYR H CA 1 ATOM 6112 C C . TYR C 3 182 ? 49.255 45.833 78.213 1.00 27.83 ? 185 TYR H C 1 ATOM 6113 O O . TYR C 3 182 ? 49.703 46.900 77.765 1.00 29.16 ? 185 TYR H O 1 ATOM 6114 C CB . TYR C 3 182 ? 50.229 44.771 80.130 1.00 23.81 ? 185 TYR H CB 1 ATOM 6115 C CG . TYR C 3 182 ? 51.063 43.701 80.777 1.00 22.93 ? 185 TYR H CG 1 ATOM 6116 C CD1 . TYR C 3 182 ? 50.533 42.481 81.137 1.00 20.83 ? 185 TYR H CD1 1 ATOM 6117 C CD2 . TYR C 3 182 ? 52.369 44.014 81.032 1.00 22.12 ? 185 TYR H CD2 1 ATOM 6118 C CE1 . TYR C 3 182 ? 51.343 41.567 81.780 1.00 19.38 ? 185 TYR H CE1 1 ATOM 6119 C CE2 . TYR C 3 182 ? 53.186 43.114 81.666 1.00 19.02 ? 185 TYR H CE2 1 ATOM 6120 C CZ . TYR C 3 182 ? 52.677 41.897 82.049 1.00 20.63 ? 185 TYR H CZ 1 ATOM 6121 O OH . TYR C 3 182 ? 53.531 41.070 82.786 1.00 21.60 ? 185 TYR H OH 1 ATOM 6122 N N . THR C 3 183 ? 47.994 45.564 78.512 1.00 28.91 ? 186 THR H N 1 ATOM 6123 C CA . THR C 3 183 ? 46.904 46.494 78.295 1.00 31.71 ? 186 THR H CA 1 ATOM 6124 C C . THR C 3 183 ? 46.008 46.409 79.548 1.00 31.29 ? 186 THR H C 1 ATOM 6125 O O . THR C 3 183 ? 45.539 45.338 79.963 1.00 30.56 ? 186 THR H O 1 ATOM 6126 C CB . THR C 3 183 ? 46.229 46.044 76.984 1.00 32.19 ? 186 THR H CB 1 ATOM 6127 O OG1 . THR C 3 183 ? 47.239 46.179 75.964 1.00 32.88 ? 186 THR H OG1 1 ATOM 6128 C CG2 . THR C 3 183 ? 44.917 46.810 76.709 1.00 32.30 ? 186 THR H CG2 1 ATOM 6129 N N . LEU C 3 184 ? 45.798 47.563 80.175 1.00 30.63 ? 187 LEU H N 1 ATOM 6130 C CA . LEU C 3 184 ? 45.141 47.700 81.470 1.00 28.49 ? 187 LEU H CA 1 ATOM 6131 C C . LEU C 3 184 ? 44.155 48.815 81.244 1.00 28.07 ? 187 LEU H C 1 ATOM 6132 O O . LEU C 3 184 ? 44.332 49.666 80.362 1.00 28.55 ? 187 LEU H O 1 ATOM 6133 C CB . LEU C 3 184 ? 46.150 48.130 82.516 1.00 28.16 ? 187 LEU H CB 1 ATOM 6134 C CG . LEU C 3 184 ? 45.791 48.341 83.969 1.00 28.72 ? 187 LEU H CG 1 ATOM 6135 C CD1 . LEU C 3 184 ? 46.403 47.258 84.830 1.00 27.68 ? 187 LEU H CD1 1 ATOM 6136 C CD2 . LEU C 3 184 ? 46.356 49.658 84.428 1.00 28.82 ? 187 LEU H CD2 1 ATOM 6137 N N . SER C 3 185 ? 43.109 48.851 82.052 1.00 26.04 ? 188 SER H N 1 ATOM 6138 C CA . SER C 3 185 ? 42.086 49.870 81.911 1.00 22.80 ? 188 SER H CA 1 ATOM 6139 C C . SER C 3 185 ? 41.348 50.004 83.236 1.00 22.71 ? 188 SER H C 1 ATOM 6140 O O . SER C 3 185 ? 41.394 49.062 84.048 1.00 21.77 ? 188 SER H O 1 ATOM 6141 C CB . SER C 3 185 ? 41.167 49.420 80.754 1.00 23.50 ? 188 SER H CB 1 ATOM 6142 O OG . SER C 3 185 ? 40.847 48.021 80.852 1.00 23.11 ? 188 SER H OG 1 ATOM 6143 N N . SER C 3 186 ? 40.734 51.161 83.487 1.00 24.03 ? 189 SER H N 1 ATOM 6144 C CA . SER C 3 186 ? 39.864 51.367 84.641 1.00 24.82 ? 189 SER H CA 1 ATOM 6145 C C . SER C 3 186 ? 38.605 52.104 84.230 1.00 25.01 ? 189 SER H C 1 ATOM 6146 O O . SER C 3 186 ? 38.637 52.822 83.218 1.00 25.41 ? 189 SER H O 1 ATOM 6147 C CB . SER C 3 186 ? 40.513 52.207 85.706 1.00 25.99 ? 189 SER H CB 1 ATOM 6148 O OG . SER C 3 186 ? 41.568 51.471 86.259 1.00 28.55 ? 189 SER H OG 1 ATOM 6149 N N . SER C 3 187 ? 37.512 51.853 84.955 1.00 24.21 ? 190 SER H N 1 ATOM 6150 C CA . SER C 3 187 ? 36.283 52.633 84.830 1.00 24.23 ? 190 SER H CA 1 ATOM 6151 C C . SER C 3 187 ? 35.905 53.343 86.129 1.00 23.07 ? 190 SER H C 1 ATOM 6152 O O . SER C 3 187 ? 36.348 52.941 87.204 1.00 21.73 ? 190 SER H O 1 ATOM 6153 C CB . SER C 3 187 ? 35.084 51.753 84.419 1.00 23.36 ? 190 SER H CB 1 ATOM 6154 O OG . SER C 3 187 ? 35.087 50.373 84.786 1.00 24.67 ? 190 SER H OG 1 ATOM 6155 N N . VAL C 3 188 ? 35.145 54.427 86.054 1.00 21.52 ? 191 VAL H N 1 ATOM 6156 C CA . VAL C 3 188 ? 34.679 55.146 87.220 1.00 20.20 ? 191 VAL H CA 1 ATOM 6157 C C . VAL C 3 188 ? 33.293 55.638 86.829 1.00 20.44 ? 191 VAL H C 1 ATOM 6158 O O . VAL C 3 188 ? 33.064 55.986 85.667 1.00 20.82 ? 191 VAL H O 1 ATOM 6159 C CB . VAL C 3 188 ? 35.665 56.335 87.579 1.00 20.90 ? 191 VAL H CB 1 ATOM 6160 C CG1 . VAL C 3 188 ? 35.600 57.563 86.693 1.00 20.43 ? 191 VAL H CG1 1 ATOM 6161 C CG2 . VAL C 3 188 ? 35.316 56.678 89.015 1.00 20.50 ? 191 VAL H CG2 1 ATOM 6162 N N . THR C 3 189 ? 32.335 55.570 87.732 1.00 21.09 ? 192 THR H N 1 ATOM 6163 C CA . THR C 3 189 ? 30.992 56.036 87.453 1.00 20.55 ? 192 THR H CA 1 ATOM 6164 C C . THR C 3 189 ? 30.731 57.246 88.348 1.00 19.81 ? 192 THR H C 1 ATOM 6165 O O . THR C 3 189 ? 31.110 57.259 89.520 1.00 16.95 ? 192 THR H O 1 ATOM 6166 C CB . THR C 3 189 ? 30.033 54.898 87.752 1.00 18.99 ? 192 THR H CB 1 ATOM 6167 O OG1 . THR C 3 189 ? 30.475 53.795 86.970 1.00 19.58 ? 192 THR H OG1 1 ATOM 6168 C CG2 . THR C 3 189 ? 28.597 55.245 87.459 1.00 18.81 ? 192 THR H CG2 1 ATOM 6169 N N . VAL C 3 190 ? 30.154 58.317 87.807 1.00 19.89 ? 193 VAL H N 1 ATOM 6170 C CA . VAL C 3 190 ? 29.806 59.488 88.576 1.00 20.47 ? 193 VAL H CA 1 ATOM 6171 C C . VAL C 3 190 ? 28.421 59.921 88.192 1.00 21.33 ? 193 VAL H C 1 ATOM 6172 O O . VAL C 3 190 ? 27.808 59.457 87.229 1.00 22.30 ? 193 VAL H O 1 ATOM 6173 C CB . VAL C 3 190 ? 30.737 60.690 88.358 1.00 19.71 ? 193 VAL H CB 1 ATOM 6174 C CG1 . VAL C 3 190 ? 32.057 60.364 88.978 1.00 20.91 ? 193 VAL H CG1 1 ATOM 6175 C CG2 . VAL C 3 190 ? 30.995 60.967 86.923 1.00 20.77 ? 193 VAL H CG2 1 ATOM 6176 N N . THR C 3 191 ? 27.893 60.791 89.027 1.00 21.51 ? 194 THR H N 1 ATOM 6177 C CA . THR C 3 191 ? 26.584 61.285 88.773 1.00 21.29 ? 194 THR H CA 1 ATOM 6178 C C . THR C 3 191 ? 26.883 62.388 87.793 1.00 21.90 ? 194 THR H C 1 ATOM 6179 O O . THR C 3 191 ? 27.976 62.970 87.651 1.00 20.89 ? 194 THR H O 1 ATOM 6180 C CB . THR C 3 191 ? 25.935 61.821 90.072 1.00 20.82 ? 194 THR H CB 1 ATOM 6181 O OG1 . THR C 3 191 ? 26.794 62.855 90.595 1.00 22.41 ? 194 THR H OG1 1 ATOM 6182 C CG2 . THR C 3 191 ? 25.634 60.668 91.037 1.00 18.84 ? 194 THR H CG2 1 ATOM 6183 N N . SER C 3 192 ? 25.779 62.617 87.137 1.00 24.68 ? 195 SER H N 1 ATOM 6184 C CA . SER C 3 192 ? 25.707 63.630 86.137 1.00 26.96 ? 195 SER H CA 1 ATOM 6185 C C . SER C 3 192 ? 26.031 64.951 86.837 1.00 26.99 ? 195 SER H C 1 ATOM 6186 O O . SER C 3 192 ? 26.794 65.697 86.248 1.00 28.83 ? 195 SER H O 1 ATOM 6187 C CB . SER C 3 192 ? 24.297 63.522 85.586 1.00 29.91 ? 195 SER H CB 1 ATOM 6188 O OG . SER C 3 192 ? 23.814 62.170 85.654 1.00 34.10 ? 195 SER H OG 1 ATOM 6189 N N . SER C 3 193 ? 25.624 65.251 88.093 1.00 27.33 ? 196 SER H N 1 ATOM 6190 C CA . SER C 3 193 ? 25.953 66.538 88.710 1.00 25.91 ? 196 SER H CA 1 ATOM 6191 C C . SER C 3 193 ? 27.457 66.835 88.756 1.00 26.29 ? 196 SER H C 1 ATOM 6192 O O . SER C 3 193 ? 27.857 67.994 88.561 1.00 26.79 ? 196 SER H O 1 ATOM 6193 C CB . SER C 3 193 ? 25.381 66.598 90.136 1.00 25.34 ? 196 SER H CB 1 ATOM 6194 O OG . SER C 3 193 ? 24.040 66.120 90.224 1.00 25.22 ? 196 SER H OG 1 ATOM 6195 N N . THR C 3 194 ? 28.257 65.767 89.018 1.00 25.62 ? 198 THR H N 1 ATOM 6196 C CA . THR C 3 194 ? 29.706 65.880 89.066 1.00 26.19 ? 198 THR H CA 1 ATOM 6197 C C . THR C 3 194 ? 30.467 65.972 87.758 1.00 25.14 ? 198 THR H C 1 ATOM 6198 O O . THR C 3 194 ? 31.522 66.618 87.797 1.00 26.63 ? 198 THR H O 1 ATOM 6199 C CB . THR C 3 194 ? 30.330 64.710 89.911 1.00 28.31 ? 198 THR H CB 1 ATOM 6200 O OG1 . THR C 3 194 ? 29.639 63.485 89.715 1.00 30.78 ? 198 THR H OG1 1 ATOM 6201 C CG2 . THR C 3 194 ? 30.221 65.045 91.383 1.00 27.58 ? 198 THR H CG2 1 ATOM 6202 N N . TRP C 3 195 ? 30.072 65.455 86.582 1.00 23.40 ? 199 TRP H N 1 ATOM 6203 C CA . TRP C 3 195 ? 30.892 65.558 85.361 1.00 21.53 ? 199 TRP H CA 1 ATOM 6204 C C . TRP C 3 195 ? 29.989 65.963 84.206 1.00 22.05 ? 199 TRP H C 1 ATOM 6205 O O . TRP C 3 195 ? 28.918 65.349 84.052 1.00 21.20 ? 199 TRP H O 1 ATOM 6206 C CB . TRP C 3 195 ? 31.590 64.180 85.041 1.00 18.23 ? 199 TRP H CB 1 ATOM 6207 C CG . TRP C 3 195 ? 32.611 64.208 83.896 1.00 17.31 ? 199 TRP H CG 1 ATOM 6208 C CD1 . TRP C 3 195 ? 33.949 64.578 84.054 1.00 16.33 ? 199 TRP H CD1 1 ATOM 6209 C CD2 . TRP C 3 195 ? 32.335 63.957 82.579 1.00 16.13 ? 199 TRP H CD2 1 ATOM 6210 N NE1 . TRP C 3 195 ? 34.498 64.575 82.851 1.00 15.55 ? 199 TRP H NE1 1 ATOM 6211 C CE2 . TRP C 3 195 ? 33.561 64.204 81.958 1.00 15.39 ? 199 TRP H CE2 1 ATOM 6212 C CE3 . TRP C 3 195 ? 31.227 63.574 81.877 1.00 13.53 ? 199 TRP H CE3 1 ATOM 6213 C CZ2 . TRP C 3 195 ? 33.695 64.066 80.608 1.00 15.15 ? 199 TRP H CZ2 1 ATOM 6214 C CZ3 . TRP C 3 195 ? 31.356 63.443 80.522 1.00 13.89 ? 199 TRP H CZ3 1 ATOM 6215 C CH2 . TRP C 3 195 ? 32.568 63.685 79.902 1.00 15.04 ? 199 TRP H CH2 1 ATOM 6216 N N . PRO C 3 196 ? 30.342 66.910 83.296 1.00 22.64 ? 200 PRO H N 1 ATOM 6217 C CA . PRO C 3 196 ? 31.645 67.558 83.087 1.00 21.17 ? 200 PRO H CA 1 ATOM 6218 C C . PRO C 3 196 ? 32.085 68.653 84.015 1.00 23.16 ? 200 PRO H C 1 ATOM 6219 O O . PRO C 3 196 ? 33.104 69.311 83.815 1.00 24.71 ? 200 PRO H O 1 ATOM 6220 C CB . PRO C 3 196 ? 31.601 68.073 81.670 1.00 22.09 ? 200 PRO H CB 1 ATOM 6221 C CG . PRO C 3 196 ? 30.583 67.176 80.969 1.00 23.17 ? 200 PRO H CG 1 ATOM 6222 C CD . PRO C 3 196 ? 29.543 67.137 82.080 1.00 23.47 ? 200 PRO H CD 1 ATOM 6223 N N . SER C 3 197 ? 31.233 68.846 85.001 1.00 26.03 ? 202 SER H N 1 ATOM 6224 C CA . SER C 3 197 ? 31.412 69.799 86.083 1.00 29.07 ? 202 SER H CA 1 ATOM 6225 C C . SER C 3 197 ? 32.776 69.809 86.811 1.00 29.21 ? 202 SER H C 1 ATOM 6226 O O . SER C 3 197 ? 33.373 70.887 86.908 1.00 28.77 ? 202 SER H O 1 ATOM 6227 C CB . SER C 3 197 ? 30.242 69.508 87.025 1.00 28.81 ? 202 SER H CB 1 ATOM 6228 O OG . SER C 3 197 ? 29.108 68.993 86.292 1.00 29.82 ? 202 SER H OG 1 ATOM 6229 N N . GLN C 3 198 ? 33.280 68.728 87.431 1.00 31.37 ? 203 GLN H N 1 ATOM 6230 C CA . GLN C 3 198 ? 34.607 68.730 88.030 1.00 32.00 ? 203 GLN H CA 1 ATOM 6231 C C . GLN C 3 198 ? 35.665 68.096 87.153 1.00 32.52 ? 203 GLN H C 1 ATOM 6232 O O . GLN C 3 198 ? 35.350 67.653 86.051 1.00 32.93 ? 203 GLN H O 1 ATOM 6233 C CB . GLN C 3 198 ? 34.545 68.031 89.382 1.00 31.99 ? 203 GLN H CB 1 ATOM 6234 C CG . GLN C 3 198 ? 33.892 68.962 90.402 1.00 32.02 ? 203 GLN H CG 1 ATOM 6235 C CD . GLN C 3 198 ? 34.636 70.280 90.588 1.00 31.95 ? 203 GLN H CD 1 ATOM 6236 O OE1 . GLN C 3 198 ? 35.561 70.376 91.386 1.00 31.62 ? 203 GLN H OE1 1 ATOM 6237 N NE2 . GLN C 3 198 ? 34.313 71.342 89.863 1.00 32.17 ? 203 GLN H NE2 1 ATOM 6238 N N . SER C 3 199 ? 36.913 67.929 87.552 1.00 33.10 ? 204 SER H N 1 ATOM 6239 C CA . SER C 3 199 ? 37.909 67.466 86.596 1.00 34.66 ? 204 SER H CA 1 ATOM 6240 C C . SER C 3 199 ? 38.304 66.047 86.916 1.00 33.89 ? 204 SER H C 1 ATOM 6241 O O . SER C 3 199 ? 39.087 65.845 87.844 1.00 36.03 ? 204 SER H O 1 ATOM 6242 C CB . SER C 3 199 ? 39.110 68.405 86.675 1.00 36.03 ? 204 SER H CB 1 ATOM 6243 O OG . SER C 3 199 ? 38.715 69.685 87.207 1.00 39.41 ? 204 SER H OG 1 ATOM 6244 N N . ILE C 3 200 ? 37.732 65.036 86.270 1.00 30.82 ? 205 ILE H N 1 ATOM 6245 C CA . ILE C 3 200 ? 38.180 63.678 86.535 1.00 28.48 ? 205 ILE H CA 1 ATOM 6246 C C . ILE C 3 200 ? 39.487 63.451 85.776 1.00 28.67 ? 205 ILE H C 1 ATOM 6247 O O . ILE C 3 200 ? 39.603 63.768 84.588 1.00 27.74 ? 205 ILE H O 1 ATOM 6248 C CB . ILE C 3 200 ? 37.048 62.726 86.122 1.00 27.46 ? 205 ILE H CB 1 ATOM 6249 C CG1 . ILE C 3 200 ? 35.881 62.888 87.121 1.00 27.20 ? 205 ILE H CG1 1 ATOM 6250 C CG2 . ILE C 3 200 ? 37.522 61.287 86.126 1.00 26.36 ? 205 ILE H CG2 1 ATOM 6251 C CD1 . ILE C 3 200 ? 34.614 62.033 86.851 1.00 25.24 ? 205 ILE H CD1 1 ATOM 6252 N N . THR C 3 201 ? 40.514 62.954 86.461 1.00 28.10 ? 206 THR H N 1 ATOM 6253 C CA . THR C 3 201 ? 41.839 62.776 85.879 1.00 25.90 ? 206 THR H CA 1 ATOM 6254 C C . THR C 3 201 ? 42.414 61.421 86.208 1.00 25.60 ? 206 THR H C 1 ATOM 6255 O O . THR C 3 201 ? 42.340 60.940 87.332 1.00 25.83 ? 206 THR H O 1 ATOM 6256 C CB . THR C 3 201 ? 42.760 63.874 86.401 1.00 26.09 ? 206 THR H CB 1 ATOM 6257 O OG1 . THR C 3 201 ? 42.098 65.067 86.032 1.00 25.85 ? 206 THR H OG1 1 ATOM 6258 C CG2 . THR C 3 201 ? 44.161 63.882 85.840 1.00 26.66 ? 206 THR H CG2 1 ATOM 6259 N N . CYS C 3 202 ? 42.904 60.774 85.180 1.00 24.74 ? 208 CYS H N 1 ATOM 6260 C CA . CYS C 3 202 ? 43.512 59.469 85.294 1.00 25.77 ? 208 CYS H CA 1 ATOM 6261 C C . CYS C 3 202 ? 44.944 59.685 85.739 1.00 27.02 ? 208 CYS H C 1 ATOM 6262 O O . CYS C 3 202 ? 45.735 60.207 84.950 1.00 27.93 ? 208 CYS H O 1 ATOM 6263 C CB . CYS C 3 202 ? 43.457 58.854 83.943 1.00 25.19 ? 208 CYS H CB 1 ATOM 6264 S SG . CYS C 3 202 ? 43.695 57.081 84.010 1.00 25.96 ? 208 CYS H SG 1 ATOM 6265 N N . ASN C 3 203 ? 45.369 59.350 86.946 1.00 27.02 ? 209 ASN H N 1 ATOM 6266 C CA . ASN C 3 203 ? 46.736 59.650 87.355 1.00 26.87 ? 209 ASN H CA 1 ATOM 6267 C C . ASN C 3 203 ? 47.558 58.360 87.302 1.00 28.11 ? 209 ASN H C 1 ATOM 6268 O O . ASN C 3 203 ? 47.610 57.570 88.264 1.00 27.28 ? 209 ASN H O 1 ATOM 6269 C CB . ASN C 3 203 ? 46.641 60.276 88.748 1.00 27.43 ? 209 ASN H CB 1 ATOM 6270 C CG . ASN C 3 203 ? 46.185 61.743 88.769 1.00 30.61 ? 209 ASN H CG 1 ATOM 6271 O OD1 . ASN C 3 203 ? 45.036 62.175 88.581 1.00 32.03 ? 209 ASN H OD1 1 ATOM 6272 N ND2 . ASN C 3 203 ? 47.136 62.610 89.069 1.00 30.75 ? 209 ASN H ND2 1 ATOM 6273 N N . VAL C 3 204 ? 48.166 58.081 86.146 1.00 29.05 ? 210 VAL H N 1 ATOM 6274 C CA . VAL C 3 204 ? 48.845 56.815 85.900 1.00 30.04 ? 210 VAL H CA 1 ATOM 6275 C C . VAL C 3 204 ? 50.369 56.857 86.049 1.00 31.89 ? 210 VAL H C 1 ATOM 6276 O O . VAL C 3 204 ? 51.077 57.564 85.319 1.00 34.68 ? 210 VAL H O 1 ATOM 6277 C CB . VAL C 3 204 ? 48.489 56.335 84.489 1.00 29.86 ? 210 VAL H CB 1 ATOM 6278 C CG1 . VAL C 3 204 ? 49.206 55.044 84.176 1.00 29.56 ? 210 VAL H CG1 1 ATOM 6279 C CG2 . VAL C 3 204 ? 47.007 56.082 84.374 1.00 28.81 ? 210 VAL H CG2 1 ATOM 6280 N N . ALA C 3 205 ? 50.949 56.029 86.900 1.00 30.43 ? 211 ALA H N 1 ATOM 6281 C CA . ALA C 3 205 ? 52.391 56.004 87.064 1.00 30.28 ? 211 ALA H CA 1 ATOM 6282 C C . ALA C 3 205 ? 52.994 54.660 86.725 1.00 28.93 ? 211 ALA H C 1 ATOM 6283 O O . ALA C 3 205 ? 52.640 53.635 87.322 1.00 28.98 ? 211 ALA H O 1 ATOM 6284 C CB . ALA C 3 205 ? 52.800 56.290 88.489 1.00 31.10 ? 211 ALA H CB 1 ATOM 6285 N N . HIS C 3 206 ? 53.882 54.661 85.733 1.00 27.76 ? 212 HIS H N 1 ATOM 6286 C CA . HIS C 3 206 ? 54.638 53.476 85.360 1.00 27.94 ? 212 HIS H CA 1 ATOM 6287 C C . HIS C 3 206 ? 55.948 53.763 86.054 1.00 31.07 ? 212 HIS H C 1 ATOM 6288 O O . HIS C 3 206 ? 56.719 54.618 85.616 1.00 30.69 ? 212 HIS H O 1 ATOM 6289 C CB . HIS C 3 206 ? 54.963 53.315 83.863 1.00 25.49 ? 212 HIS H CB 1 ATOM 6290 C CG . HIS C 3 206 ? 55.412 51.884 83.586 1.00 24.42 ? 212 HIS H CG 1 ATOM 6291 N ND1 . HIS C 3 206 ? 56.629 51.415 83.305 1.00 23.57 ? 212 HIS H ND1 1 ATOM 6292 C CD2 . HIS C 3 206 ? 54.563 50.803 83.611 1.00 24.86 ? 212 HIS H CD2 1 ATOM 6293 C CE1 . HIS C 3 206 ? 56.553 50.108 83.154 1.00 23.23 ? 212 HIS H CE1 1 ATOM 6294 N NE2 . HIS C 3 206 ? 55.302 49.755 83.346 1.00 24.61 ? 212 HIS H NE2 1 ATOM 6295 N N . PRO C 3 207 ? 56.221 53.080 87.165 1.00 33.65 ? 213 PRO H N 1 ATOM 6296 C CA . PRO C 3 207 ? 57.433 53.262 87.925 1.00 34.39 ? 213 PRO H CA 1 ATOM 6297 C C . PRO C 3 207 ? 58.663 52.640 87.277 1.00 34.82 ? 213 PRO H C 1 ATOM 6298 O O . PRO C 3 207 ? 59.751 53.142 87.509 1.00 35.54 ? 213 PRO H O 1 ATOM 6299 C CB . PRO C 3 207 ? 57.047 52.695 89.264 1.00 34.80 ? 213 PRO H CB 1 ATOM 6300 C CG . PRO C 3 207 ? 56.095 51.546 88.970 1.00 34.52 ? 213 PRO H CG 1 ATOM 6301 C CD . PRO C 3 207 ? 55.341 52.058 87.764 1.00 33.85 ? 213 PRO H CD 1 ATOM 6302 N N . ALA C 3 208 ? 58.581 51.595 86.451 1.00 35.45 ? 214 ALA H N 1 ATOM 6303 C CA . ALA C 3 208 ? 59.772 51.042 85.823 1.00 35.44 ? 214 ALA H CA 1 ATOM 6304 C C . ALA C 3 208 ? 60.393 52.020 84.821 1.00 35.64 ? 214 ALA H C 1 ATOM 6305 O O . ALA C 3 208 ? 61.611 52.196 84.758 1.00 34.91 ? 214 ALA H O 1 ATOM 6306 C CB . ALA C 3 208 ? 59.412 49.762 85.092 1.00 36.57 ? 214 ALA H CB 1 ATOM 6307 N N . SER C 3 209 ? 59.592 52.697 84.006 1.00 36.39 ? 215 SER H N 1 ATOM 6308 C CA . SER C 3 209 ? 60.100 53.678 83.067 1.00 36.37 ? 215 SER H CA 1 ATOM 6309 C C . SER C 3 209 ? 60.122 55.138 83.533 1.00 38.20 ? 215 SER H C 1 ATOM 6310 O O . SER C 3 209 ? 60.374 56.012 82.693 1.00 40.86 ? 215 SER H O 1 ATOM 6311 C CB . SER C 3 209 ? 59.275 53.540 81.822 1.00 36.19 ? 215 SER H CB 1 ATOM 6312 O OG . SER C 3 209 ? 57.869 53.474 82.116 1.00 34.41 ? 215 SER H OG 1 ATOM 6313 N N . SER C 3 210 ? 59.887 55.467 84.818 1.00 38.68 ? 216 SER H N 1 ATOM 6314 C CA . SER C 3 210 ? 59.827 56.841 85.309 1.00 39.83 ? 216 SER H CA 1 ATOM 6315 C C . SER C 3 210 ? 58.847 57.659 84.458 1.00 39.46 ? 216 SER H C 1 ATOM 6316 O O . SER C 3 210 ? 59.125 58.637 83.753 1.00 40.19 ? 216 SER H O 1 ATOM 6317 C CB . SER C 3 210 ? 61.262 57.437 85.290 1.00 40.94 ? 216 SER H CB 1 ATOM 6318 O OG . SER C 3 210 ? 62.267 56.597 85.896 1.00 41.94 ? 216 SER H OG 1 ATOM 6319 N N . THR C 3 211 ? 57.627 57.163 84.535 1.00 38.50 ? 217 THR H N 1 ATOM 6320 C CA . THR C 3 211 ? 56.551 57.697 83.754 1.00 38.67 ? 217 THR H CA 1 ATOM 6321 C C . THR C 3 211 ? 55.400 58.034 84.705 1.00 38.48 ? 217 THR H C 1 ATOM 6322 O O . THR C 3 211 ? 55.012 57.195 85.510 1.00 38.16 ? 217 THR H O 1 ATOM 6323 C CB . THR C 3 211 ? 56.203 56.607 82.730 1.00 38.76 ? 217 THR H CB 1 ATOM 6324 O OG1 . THR C 3 211 ? 57.404 56.161 82.121 1.00 37.38 ? 217 THR H OG1 1 ATOM 6325 C CG2 . THR C 3 211 ? 55.264 57.114 81.664 1.00 39.20 ? 217 THR H CG2 1 ATOM 6326 N N . LYS C 3 212 ? 54.849 59.239 84.725 1.00 38.20 ? 218 LYS H N 1 ATOM 6327 C CA . LYS C 3 212 ? 53.702 59.593 85.532 1.00 38.48 ? 218 LYS H CA 1 ATOM 6328 C C . LYS C 3 212 ? 52.898 60.484 84.583 1.00 37.91 ? 218 LYS H C 1 ATOM 6329 O O . LYS C 3 212 ? 53.412 61.410 83.948 1.00 37.97 ? 218 LYS H O 1 ATOM 6330 C CB . LYS C 3 212 ? 54.125 60.368 86.790 1.00 40.06 ? 218 LYS H CB 1 ATOM 6331 C CG . LYS C 3 212 ? 54.654 59.475 87.917 1.00 42.79 ? 218 LYS H CG 1 ATOM 6332 C CD . LYS C 3 212 ? 56.164 59.165 87.874 1.00 44.92 ? 218 LYS H CD 1 ATOM 6333 C CE . LYS C 3 212 ? 56.589 57.862 88.604 1.00 46.05 ? 218 LYS H CE 1 ATOM 6334 N NZ . LYS C 3 212 ? 56.418 56.634 87.824 1.00 45.97 ? 218 LYS H NZ 1 ATOM 6335 N N . VAL C 3 213 ? 51.635 60.152 84.402 1.00 36.77 ? 219 VAL H N 1 ATOM 6336 C CA . VAL C 3 213 ? 50.748 60.804 83.449 1.00 35.70 ? 219 VAL H CA 1 ATOM 6337 C C . VAL C 3 213 ? 49.524 61.169 84.255 1.00 33.48 ? 219 VAL H C 1 ATOM 6338 O O . VAL C 3 213 ? 49.258 60.495 85.266 1.00 31.97 ? 219 VAL H O 1 ATOM 6339 C CB . VAL C 3 213 ? 50.308 59.834 82.295 1.00 34.99 ? 219 VAL H CB 1 ATOM 6340 C CG1 . VAL C 3 213 ? 49.332 60.567 81.376 1.00 35.45 ? 219 VAL H CG1 1 ATOM 6341 C CG2 . VAL C 3 213 ? 51.493 59.379 81.455 1.00 35.43 ? 219 VAL H CG2 1 ATOM 6342 N N . ASP C 3 214 ? 48.820 62.226 83.820 1.00 32.08 ? 220 ASP H N 1 ATOM 6343 C CA . ASP C 3 214 ? 47.544 62.619 84.401 1.00 31.22 ? 220 ASP H CA 1 ATOM 6344 C C . ASP C 3 214 ? 46.567 62.892 83.260 1.00 30.03 ? 220 ASP H C 1 ATOM 6345 O O . ASP C 3 214 ? 46.242 64.055 83.017 1.00 32.17 ? 220 ASP H O 1 ATOM 6346 C CB . ASP C 3 214 ? 47.628 63.916 85.236 1.00 34.06 ? 220 ASP H CB 1 ATOM 6347 C CG . ASP C 3 214 ? 48.604 64.117 86.407 1.00 35.29 ? 220 ASP H CG 1 ATOM 6348 O OD1 . ASP C 3 214 ? 49.284 63.181 86.860 1.00 35.60 ? 220 ASP H OD1 1 ATOM 6349 O OD2 . ASP C 3 214 ? 48.658 65.267 86.883 1.00 37.51 ? 220 ASP H OD2 1 ATOM 6350 N N . LYS C 3 215 ? 46.035 61.947 82.477 1.00 28.99 ? 221 LYS H N 1 ATOM 6351 C CA . LYS C 3 215 ? 45.133 62.320 81.381 1.00 28.87 ? 221 LYS H CA 1 ATOM 6352 C C . LYS C 3 215 ? 43.809 62.829 81.920 1.00 27.67 ? 221 LYS H C 1 ATOM 6353 O O . LYS C 3 215 ? 43.082 62.102 82.603 1.00 29.02 ? 221 LYS H O 1 ATOM 6354 C CB . LYS C 3 215 ? 44.813 61.150 80.481 1.00 28.75 ? 221 LYS H CB 1 ATOM 6355 C CG . LYS C 3 215 ? 45.536 61.143 79.172 1.00 31.84 ? 221 LYS H CG 1 ATOM 6356 C CD . LYS C 3 215 ? 45.403 62.489 78.487 1.00 34.92 ? 221 LYS H CD 1 ATOM 6357 C CE . LYS C 3 215 ? 45.811 62.423 77.013 1.00 36.69 ? 221 LYS H CE 1 ATOM 6358 N NZ . LYS C 3 215 ? 47.167 61.944 76.788 1.00 38.96 ? 221 LYS H NZ 1 ATOM 6359 N N . LYS C 3 216 ? 43.493 64.094 81.716 1.00 25.30 ? 222 LYS H N 1 ATOM 6360 C CA . LYS C 3 216 ? 42.197 64.634 82.105 1.00 26.62 ? 222 LYS H CA 1 ATOM 6361 C C . LYS C 3 216 ? 41.133 64.055 81.179 1.00 27.04 ? 222 LYS H C 1 ATOM 6362 O O . LYS C 3 216 ? 41.277 64.094 79.955 1.00 27.21 ? 222 LYS H O 1 ATOM 6363 C CB . LYS C 3 216 ? 42.238 66.152 81.995 1.00 24.61 ? 222 LYS H CB 1 ATOM 6364 C CG . LYS C 3 216 ? 41.043 66.928 82.527 1.00 23.47 ? 222 LYS H CG 1 ATOM 6365 C CD . LYS C 3 216 ? 41.442 68.383 82.373 1.00 22.98 ? 222 LYS H CD 1 ATOM 6366 C CE . LYS C 3 216 ? 40.430 69.359 82.931 1.00 22.81 ? 222 LYS H CE 1 ATOM 6367 N NZ . LYS C 3 216 ? 41.084 70.649 83.025 1.00 22.68 ? 222 LYS H NZ 1 ATOM 6368 N N . ILE C 3 217 ? 40.067 63.444 81.682 1.00 27.06 ? 223 ILE H N 1 ATOM 6369 C CA . ILE C 3 217 ? 38.989 63.028 80.802 1.00 26.68 ? 223 ILE H CA 1 ATOM 6370 C C . ILE C 3 217 ? 38.168 64.311 80.635 1.00 29.77 ? 223 ILE H C 1 ATOM 6371 O O . ILE C 3 217 ? 37.433 64.772 81.524 1.00 30.38 ? 223 ILE H O 1 ATOM 6372 C CB . ILE C 3 217 ? 38.151 61.870 81.436 1.00 25.34 ? 223 ILE H CB 1 ATOM 6373 C CG1 . ILE C 3 217 ? 38.846 60.537 81.200 1.00 23.15 ? 223 ILE H CG1 1 ATOM 6374 C CG2 . ILE C 3 217 ? 36.785 61.748 80.764 1.00 24.38 ? 223 ILE H CG2 1 ATOM 6375 C CD1 . ILE C 3 217 ? 40.165 60.352 81.951 1.00 24.31 ? 223 ILE H CD1 1 ATOM 6376 N N . GLU C 3 218 ? 38.470 64.937 79.490 1.00 33.04 ? 224 GLU H N 1 ATOM 6377 C CA . GLU C 3 218 ? 37.808 66.126 78.976 1.00 31.16 ? 224 GLU H CA 1 ATOM 6378 C C . GLU C 3 218 ? 36.526 65.686 78.261 1.00 34.22 ? 224 GLU H C 1 ATOM 6379 O O . GLU C 3 218 ? 36.545 64.748 77.468 1.00 33.05 ? 224 GLU H O 1 ATOM 6380 C CB . GLU C 3 218 ? 38.797 66.820 78.040 1.00 30.43 ? 224 GLU H CB 1 ATOM 6381 C CG . GLU C 3 218 ? 38.239 67.934 77.146 1.00 27.47 ? 224 GLU H CG 1 ATOM 6382 C CD . GLU C 3 218 ? 38.242 67.620 75.652 1.00 25.78 ? 224 GLU H CD 1 ATOM 6383 O OE1 . GLU C 3 218 ? 38.240 66.452 75.268 1.00 24.64 ? 224 GLU H OE1 1 ATOM 6384 O OE2 . GLU C 3 218 ? 38.240 68.559 74.859 1.00 24.55 ? 224 GLU H OE2 1 ATOM 6385 N N . PRO C 3 219 ? 35.382 66.332 78.475 1.00 40.58 ? 225 PRO H N 1 ATOM 6386 C CA . PRO C 3 219 ? 34.098 66.036 77.857 1.00 40.01 ? 225 PRO H CA 1 ATOM 6387 C C . PRO C 3 219 ? 33.916 65.661 76.415 1.00 40.59 ? 225 PRO H C 1 ATOM 6388 O O . PRO C 3 219 ? 32.835 65.157 76.169 1.00 44.22 ? 225 PRO H O 1 ATOM 6389 C CB . PRO C 3 219 ? 33.209 67.226 78.183 1.00 40.43 ? 225 PRO H CB 1 ATOM 6390 C CG . PRO C 3 219 ? 34.045 68.167 79.040 1.00 42.10 ? 225 PRO H CG 1 ATOM 6391 C CD . PRO C 3 219 ? 35.142 67.253 79.588 1.00 41.14 ? 225 PRO H CD 1 ATOM 6392 N N . ARG C 3 220 ? 34.857 65.811 75.490 1.00 40.74 ? 226 ARG H N 1 ATOM 6393 C CA . ARG C 3 220 ? 34.700 65.483 74.068 1.00 40.92 ? 226 ARG H CA 1 ATOM 6394 C C . ARG C 3 220 ? 33.487 64.700 73.508 1.00 41.39 ? 226 ARG H C 1 ATOM 6395 O O . ARG C 3 220 ? 33.499 63.482 73.250 1.00 42.63 ? 226 ARG H O 1 ATOM 6396 C CB . ARG C 3 220 ? 35.978 64.765 73.581 1.00 40.44 ? 226 ARG H CB 1 ATOM 6397 C CG . ARG C 3 220 ? 36.327 63.423 74.228 1.00 40.02 ? 226 ARG H CG 1 ATOM 6398 C CD . ARG C 3 220 ? 37.226 62.627 73.293 1.00 39.78 ? 226 ARG H CD 1 ATOM 6399 N NE . ARG C 3 220 ? 37.160 61.200 73.578 1.00 38.65 ? 226 ARG H NE 1 ATOM 6400 C CZ . ARG C 3 220 ? 36.508 60.336 72.788 1.00 37.85 ? 226 ARG H CZ 1 ATOM 6401 N NH1 . ARG C 3 220 ? 35.874 60.722 71.677 1.00 36.98 ? 226 ARG H NH1 1 ATOM 6402 N NH2 . ARG C 3 220 ? 36.494 59.046 73.113 1.00 36.88 ? 226 ARG H NH2 1 ATOM 6403 N N . GLY C 3 221 ? 32.455 65.500 73.240 1.00 41.14 ? 227 GLY H N 1 ATOM 6404 C CA . GLY C 3 221 ? 31.178 65.044 72.722 1.00 39.96 ? 227 GLY H CA 1 ATOM 6405 C C . GLY C 3 221 ? 30.402 66.226 72.137 1.00 39.20 ? 227 GLY H C 1 ATOM 6406 O O . GLY C 3 221 ? 30.990 67.294 71.941 1.00 38.71 ? 227 GLY H O 1 ATOM 6407 O OXT . GLY C 3 221 ? 29.209 66.086 71.879 1.00 38.66 ? 227 GLY H OXT 1 HETATM 6408 C C1 . NAG D 4 . A 45.202 -10.807 130.701 1.00 10.60 ? 469 NAG N C1 1 HETATM 6409 C C2 . NAG D 4 . A 44.349 -11.494 129.667 1.00 13.08 ? 469 NAG N C2 1 HETATM 6410 C C3 . NAG D 4 . A 43.673 -12.758 130.246 1.00 12.70 ? 469 NAG N C3 1 HETATM 6411 C C4 . NAG D 4 . A 44.740 -13.653 130.879 1.00 10.50 ? 469 NAG N C4 1 HETATM 6412 C C5 . NAG D 4 . A 45.487 -12.840 131.898 1.00 8.19 ? 469 NAG N C5 1 HETATM 6413 C C6 . NAG D 4 . A 46.545 -13.598 132.679 1.00 6.35 ? 469 NAG N C6 1 HETATM 6414 C C7 . NAG D 4 . A 43.246 -10.025 128.016 1.00 22.01 ? 469 NAG N C7 1 HETATM 6415 C C8 . NAG D 4 . A 42.133 -9.017 127.763 1.00 22.58 ? 469 NAG N C8 1 HETATM 6416 N N2 . NAG D 4 . A 43.313 -10.578 129.235 1.00 18.23 ? 469 NAG N N2 1 HETATM 6417 O O3 . NAG D 4 . A 43.036 -13.408 129.177 1.00 13.66 ? 469 NAG N O3 1 HETATM 6418 O O4 . NAG D 4 . A 44.155 -14.812 131.495 1.00 11.32 ? 469 NAG N O4 1 HETATM 6419 O O5 . NAG D 4 . A 46.119 -11.760 131.221 1.00 7.99 ? 469 NAG N O5 1 HETATM 6420 O O6 . NAG D 4 . A 47.516 -14.204 131.854 1.00 6.20 ? 469 NAG N O6 1 HETATM 6421 O O7 . NAG D 4 . A 44.002 -10.342 127.100 1.00 24.42 ? 469 NAG N O7 1 HETATM 6422 C C1 . NAG E 4 . B 44.907 -16.043 131.412 1.00 12.27 ? 470 NAG N C1 1 HETATM 6423 C C2 . NAG E 4 . B 44.277 -17.074 132.299 1.00 13.34 ? 470 NAG N C2 1 HETATM 6424 C C3 . NAG E 4 . B 44.948 -18.425 132.084 1.00 15.11 ? 470 NAG N C3 1 HETATM 6425 C C4 . NAG E 4 . B 44.767 -18.804 130.575 1.00 15.36 ? 470 NAG N C4 1 HETATM 6426 C C5 . NAG E 4 . B 45.321 -17.686 129.660 1.00 13.82 ? 470 NAG N C5 1 HETATM 6427 C C6 . NAG E 4 . B 44.838 -17.831 128.221 1.00 14.92 ? 470 NAG N C6 1 HETATM 6428 C C7 . NAG E 4 . B 43.600 -15.843 134.325 1.00 16.43 ? 470 NAG N C7 1 HETATM 6429 C C8 . NAG E 4 . B 43.897 -15.513 135.783 1.00 16.63 ? 470 NAG N C8 1 HETATM 6430 N N2 . NAG E 4 . B 44.443 -16.658 133.686 1.00 15.28 ? 470 NAG N N2 1 HETATM 6431 O O3 . NAG E 4 . B 44.456 -19.418 132.962 1.00 13.87 ? 470 NAG N O3 1 HETATM 6432 O O4 . NAG E 4 . B 45.516 -20.022 130.259 1.00 14.99 ? 470 NAG N O4 1 HETATM 6433 O O5 . NAG E 4 . B 44.867 -16.409 130.061 1.00 14.47 ? 470 NAG N O5 1 HETATM 6434 O O6 . NAG E 4 . B 43.426 -17.584 128.232 1.00 18.35 ? 470 NAG N O6 1 HETATM 6435 O O7 . NAG E 4 . B 42.620 -15.362 133.755 1.00 17.59 ? 470 NAG N O7 1 HETATM 6436 C C1 . BMA F 5 . C 44.824 -21.174 129.780 1.00 13.34 ? 471 BMA N C1 1 HETATM 6437 C C2 . BMA F 5 . C 45.838 -22.034 129.063 1.00 10.51 ? 471 BMA N C2 1 HETATM 6438 C C3 . BMA F 5 . C 45.328 -23.453 128.882 1.00 11.51 ? 471 BMA N C3 1 HETATM 6439 C C4 . BMA F 5 . C 44.693 -24.008 130.173 1.00 12.90 ? 471 BMA N C4 1 HETATM 6440 C C5 . BMA F 5 . C 43.613 -23.042 130.638 1.00 12.03 ? 471 BMA N C5 1 HETATM 6441 C C6 . BMA F 5 . C 42.811 -23.471 131.877 1.00 13.36 ? 471 BMA N C6 1 HETATM 6442 O O2 . BMA F 5 . C 47.021 -22.060 129.785 1.00 8.16 ? 471 BMA N O2 1 HETATM 6443 O O3 . BMA F 5 . C 46.432 -24.326 128.524 1.00 10.19 ? 471 BMA N O3 1 HETATM 6444 O O4 . BMA F 5 . C 44.134 -25.315 129.937 1.00 15.02 ? 471 BMA N O4 1 HETATM 6445 O O5 . BMA F 5 . C 44.283 -21.823 130.908 1.00 13.50 ? 471 BMA N O5 1 HETATM 6446 O O6 . BMA F 5 . C 41.578 -22.757 132.013 1.00 14.80 ? 471 BMA N O6 1 HETATM 6447 C C1 . MAN G 6 . D 46.191 -25.184 127.440 1.00 8.95 ? 472 MAN N C1 1 HETATM 6448 C C2 . MAN G 6 . D 47.308 -26.164 127.256 1.00 11.08 ? 472 MAN N C2 1 HETATM 6449 C C3 . MAN G 6 . D 48.559 -25.462 126.768 1.00 12.98 ? 472 MAN N C3 1 HETATM 6450 C C4 . MAN G 6 . D 48.229 -24.631 125.520 1.00 11.95 ? 472 MAN N C4 1 HETATM 6451 C C5 . MAN G 6 . D 47.146 -23.633 125.866 1.00 12.95 ? 472 MAN N C5 1 HETATM 6452 C C6 . MAN G 6 . D 46.788 -22.675 124.721 1.00 14.33 ? 472 MAN N C6 1 HETATM 6453 O O2 . MAN G 6 . D 46.800 -27.045 126.252 1.00 13.45 ? 472 MAN N O2 1 HETATM 6454 O O3 . MAN G 6 . D 49.609 -26.351 126.468 1.00 14.06 ? 472 MAN N O3 1 HETATM 6455 O O4 . MAN G 6 . D 49.393 -23.976 125.087 1.00 10.74 ? 472 MAN N O4 1 HETATM 6456 O O5 . MAN G 6 . D 45.993 -24.384 126.261 1.00 10.56 ? 472 MAN N O5 1 HETATM 6457 O O6 . MAN G 6 . D 45.726 -21.800 125.122 1.00 18.48 ? 472 MAN N O6 1 HETATM 6458 C C1 . MAN H 6 . E 47.563 -28.200 125.879 1.00 15.89 ? 473 MAN N C1 1 HETATM 6459 C C2 . MAN H 6 . E 46.739 -28.981 124.863 1.00 17.08 ? 473 MAN N C2 1 HETATM 6460 C C3 . MAN H 6 . E 45.472 -29.577 125.531 1.00 17.99 ? 473 MAN N C3 1 HETATM 6461 C C4 . MAN H 6 . E 45.759 -30.239 126.872 1.00 18.13 ? 473 MAN N C4 1 HETATM 6462 C C5 . MAN H 6 . E 46.696 -29.417 127.808 1.00 18.71 ? 473 MAN N C5 1 HETATM 6463 C C6 . MAN H 6 . E 47.111 -30.362 128.985 1.00 18.06 ? 473 MAN N C6 1 HETATM 6464 O O2 . MAN H 6 . E 47.546 -30.041 124.351 1.00 15.38 ? 473 MAN N O2 1 HETATM 6465 O O3 . MAN H 6 . E 44.876 -30.594 124.721 1.00 19.49 ? 473 MAN N O3 1 HETATM 6466 O O4 . MAN H 6 . E 44.525 -30.435 127.574 1.00 20.13 ? 473 MAN N O4 1 HETATM 6467 O O5 . MAN H 6 . E 47.886 -28.976 127.059 1.00 17.89 ? 473 MAN N O5 1 HETATM 6468 O O6 . MAN H 6 . E 47.589 -31.634 128.578 1.00 15.03 ? 473 MAN N O6 1 HETATM 6469 C C1 . MAN I 6 . F 48.000 -30.030 123.001 1.00 13.54 ? 474 MAN N C1 1 HETATM 6470 C C2 . MAN I 6 . F 48.472 -31.451 122.714 1.00 12.14 ? 474 MAN N C2 1 HETATM 6471 C C3 . MAN I 6 . F 49.739 -31.682 123.483 1.00 12.81 ? 474 MAN N C3 1 HETATM 6472 C C4 . MAN I 6 . F 50.778 -30.666 123.195 1.00 13.60 ? 474 MAN N C4 1 HETATM 6473 C C5 . MAN I 6 . F 50.258 -29.310 123.605 1.00 15.61 ? 474 MAN N C5 1 HETATM 6474 C C6 . MAN I 6 . F 51.342 -28.201 123.388 1.00 15.58 ? 474 MAN N C6 1 HETATM 6475 O O2 . MAN I 6 . F 48.680 -31.690 121.349 1.00 11.49 ? 474 MAN N O2 1 HETATM 6476 O O3 . MAN I 6 . F 50.296 -32.907 123.129 1.00 14.66 ? 474 MAN N O3 1 HETATM 6477 O O4 . MAN I 6 . F 51.910 -31.059 123.925 1.00 14.70 ? 474 MAN N O4 1 HETATM 6478 O O5 . MAN I 6 . F 49.053 -29.093 122.806 1.00 13.92 ? 474 MAN N O5 1 HETATM 6479 O O6 . MAN I 6 . F 50.812 -26.957 122.940 1.00 16.88 ? 474 MAN N O6 1 HETATM 6480 C C1 . NAG J 4 . A 60.344 12.787 160.281 1.00 37.36 ? 475 NAG N C1 1 HETATM 6481 C C2 . NAG J 4 . A 61.074 12.640 161.606 1.00 39.68 ? 475 NAG N C2 1 HETATM 6482 C C3 . NAG J 4 . A 60.159 11.996 162.615 1.00 40.69 ? 475 NAG N C3 1 HETATM 6483 C C4 . NAG J 4 . A 58.882 12.885 162.702 1.00 41.17 ? 475 NAG N C4 1 HETATM 6484 C C5 . NAG J 4 . A 58.171 12.833 161.335 1.00 39.87 ? 475 NAG N C5 1 HETATM 6485 C C6 . NAG J 4 . A 56.859 13.655 161.234 1.00 40.21 ? 475 NAG N C6 1 HETATM 6486 C C7 . NAG J 4 . A 63.328 12.243 160.769 1.00 45.55 ? 475 NAG N C7 1 HETATM 6487 C C8 . NAG J 4 . A 64.479 11.296 160.464 1.00 44.79 ? 475 NAG N C8 1 HETATM 6488 N N2 . NAG J 4 . A 62.231 11.776 161.378 1.00 43.59 ? 475 NAG N N2 1 HETATM 6489 O O3 . NAG J 4 . A 60.827 11.868 163.856 1.00 41.67 ? 475 NAG N O3 1 HETATM 6490 O O4 . NAG J 4 . A 58.028 12.454 163.739 1.00 41.03 ? 475 NAG N O4 1 HETATM 6491 O O5 . NAG J 4 . A 59.064 13.364 160.385 1.00 39.02 ? 475 NAG N O5 1 HETATM 6492 O O6 . NAG J 4 . A 57.160 15.024 160.905 1.00 40.36 ? 475 NAG N O6 1 HETATM 6493 O O7 . NAG J 4 . A 63.402 13.449 160.480 1.00 45.81 ? 475 NAG N O7 1 HETATM 6494 C C1 . NAG K 4 . A 63.792 0.143 109.066 1.00 42.08 ? 476 NAG N C1 1 HETATM 6495 C C2 . NAG K 4 . A 62.300 0.258 108.813 1.00 47.12 ? 476 NAG N C2 1 HETATM 6496 C C3 . NAG K 4 . A 62.005 0.115 107.298 1.00 47.96 ? 476 NAG N C3 1 HETATM 6497 C C4 . NAG K 4 . A 62.859 1.117 106.536 1.00 47.96 ? 476 NAG N C4 1 HETATM 6498 C C5 . NAG K 4 . A 64.337 0.956 106.900 1.00 46.51 ? 476 NAG N C5 1 HETATM 6499 C C6 . NAG K 4 . A 65.386 1.832 106.225 1.00 47.02 ? 476 NAG N C6 1 HETATM 6500 C C7 . NAG K 4 . A 61.576 -2.045 109.546 1.00 53.69 ? 476 NAG N C7 1 HETATM 6501 C C8 . NAG K 4 . A 60.553 -2.710 110.446 1.00 53.34 ? 476 NAG N C8 1 HETATM 6502 N N2 . NAG K 4 . A 61.500 -0.709 109.566 1.00 51.01 ? 476 NAG N N2 1 HETATM 6503 O O3 . NAG K 4 . A 60.629 0.351 107.075 1.00 48.36 ? 476 NAG N O3 1 HETATM 6504 O O4 . NAG K 4 . A 62.730 0.956 105.120 1.00 51.50 ? 476 NAG N O4 1 HETATM 6505 O O5 . NAG K 4 . A 64.472 1.138 108.316 1.00 44.35 ? 476 NAG N O5 1 HETATM 6506 O O6 . NAG K 4 . A 66.484 1.987 107.117 1.00 47.07 ? 476 NAG N O6 1 HETATM 6507 O O7 . NAG K 4 . A 62.372 -2.706 108.863 1.00 56.37 ? 476 NAG N O7 1 HETATM 6508 C C1 . NAG L 4 . B 61.474 1.089 104.412 1.00 55.55 ? 477 NAG N C1 1 HETATM 6509 C C2 . NAG L 4 . B 61.804 1.178 102.899 1.00 57.13 ? 477 NAG N C2 1 HETATM 6510 C C3 . NAG L 4 . B 60.502 1.558 102.213 1.00 57.75 ? 477 NAG N C3 1 HETATM 6511 C C4 . NAG L 4 . B 59.538 0.377 102.444 1.00 58.18 ? 477 NAG N C4 1 HETATM 6512 C C5 . NAG L 4 . B 59.310 0.113 103.940 1.00 57.37 ? 477 NAG N C5 1 HETATM 6513 C C6 . NAG L 4 . B 58.492 -1.161 104.180 1.00 57.75 ? 477 NAG N C6 1 HETATM 6514 C C7 . NAG L 4 . B 64.178 1.719 102.497 1.00 59.49 ? 477 NAG N C7 1 HETATM 6515 C C8 . NAG L 4 . B 65.254 2.809 102.346 1.00 58.51 ? 477 NAG N C8 1 HETATM 6516 N N2 . NAG L 4 . B 62.884 2.119 102.594 1.00 58.43 ? 477 NAG N N2 1 HETATM 6517 O O3 . NAG L 4 . B 60.705 1.856 100.842 1.00 58.69 ? 477 NAG N O3 1 HETATM 6518 O O4 . NAG L 4 . B 58.306 0.692 101.841 1.00 60.12 ? 477 NAG N O4 1 HETATM 6519 O O5 . NAG L 4 . B 60.582 -0.033 104.597 1.00 56.35 ? 477 NAG N O5 1 HETATM 6520 O O6 . NAG L 4 . B 58.100 -1.224 105.542 1.00 57.92 ? 477 NAG N O6 1 HETATM 6521 O O7 . NAG L 4 . B 64.488 0.512 102.453 1.00 61.03 ? 477 NAG N O7 1 HETATM 6522 CA CA . CA M 7 . ? 46.599 19.799 126.473 1.00 27.49 ? 0 CA N CA 1 HETATM 6523 O O . HOH N 8 . ? 59.254 11.308 119.659 1.00 23.06 ? 4 HOH N O 1 HETATM 6524 O O . HOH N 8 . ? 74.296 21.996 148.053 1.00 18.71 ? 7 HOH N O 1 HETATM 6525 O O . HOH N 8 . ? 64.878 0.446 155.065 1.00 32.87 ? 8 HOH N O 1 HETATM 6526 O O . HOH N 8 . ? 78.059 35.552 144.368 1.00 40.04 ? 9 HOH N O 1 HETATM 6527 O O . HOH N 8 . ? 69.103 20.584 144.423 1.00 38.76 ? 11 HOH N O 1 HETATM 6528 O O . HOH N 8 . ? 42.026 29.372 143.150 1.00 39.76 ? 12 HOH N O 1 HETATM 6529 O O . HOH N 8 . ? 70.893 2.842 148.568 1.00 38.19 ? 13 HOH N O 1 HETATM 6530 O O . HOH N 8 . ? 52.062 30.457 143.067 1.00 38.53 ? 14 HOH N O 1 HETATM 6531 O O . HOH N 8 . ? 81.756 9.750 130.770 1.00 26.87 ? 15 HOH N O 1 HETATM 6532 O O . HOH N 8 . ? 80.986 12.432 128.203 1.00 16.40 ? 16 HOH N O 1 HETATM 6533 O O . HOH N 8 . ? 75.362 4.346 118.972 1.00 4.29 ? 17 HOH N O 1 HETATM 6534 O O . HOH N 8 . ? 47.841 20.796 130.636 1.00 19.89 ? 18 HOH N O 1 HETATM 6535 O O . HOH N 8 . ? 52.157 8.155 126.373 1.00 43.51 ? 19 HOH N O 1 HETATM 6536 O O . HOH N 8 . ? 62.127 -0.743 121.399 1.00 45.28 ? 20 HOH N O 1 HETATM 6537 O O . HOH N 8 . ? 71.806 20.001 143.880 1.00 39.34 ? 21 HOH N O 1 HETATM 6538 O O . HOH N 8 . ? 46.126 -2.013 131.032 1.00 23.40 ? 22 HOH N O 1 HETATM 6539 O O . HOH N 8 . ? 69.381 21.406 147.783 1.00 36.95 ? 23 HOH N O 1 HETATM 6540 O O . HOH N 8 . ? 70.169 8.984 124.806 1.00 15.90 ? 24 HOH N O 1 HETATM 6541 O O . HOH N 8 . ? 68.342 29.513 144.475 1.00 21.31 ? 25 HOH N O 1 HETATM 6542 O O . HOH N 8 . ? 59.925 12.390 131.404 1.00 23.92 ? 26 HOH N O 1 HETATM 6543 O O . HOH N 8 . ? 62.700 13.904 138.020 1.00 37.44 ? 27 HOH N O 1 HETATM 6544 O O . HOH N 8 . ? 51.996 28.921 145.284 1.00 47.03 ? 28 HOH N O 1 HETATM 6545 O O . HOH N 8 . ? 65.099 10.073 144.942 1.00 34.87 ? 29 HOH N O 1 HETATM 6546 O O . HOH N 8 . ? 66.997 36.438 134.402 1.00 13.38 ? 30 HOH N O 1 HETATM 6547 O O . HOH N 8 . ? 60.427 7.272 132.532 1.00 11.01 ? 31 HOH N O 1 HETATM 6548 O O . HOH N 8 . ? 51.452 9.649 131.483 1.00 30.67 ? 32 HOH N O 1 HETATM 6549 O O . HOH N 8 . ? 54.329 12.347 124.129 1.00 40.25 ? 33 HOH N O 1 HETATM 6550 O O . HOH N 8 . ? 77.120 10.781 139.435 1.00 25.10 ? 34 HOH N O 1 HETATM 6551 O O . HOH N 8 . ? 67.375 -4.483 129.039 1.00 22.99 ? 35 HOH N O 1 HETATM 6552 O O . HOH N 8 . ? 66.754 -2.219 127.486 1.00 44.30 ? 36 HOH N O 1 HETATM 6553 O O . HOH N 8 . ? 76.561 3.054 136.461 1.00 33.11 ? 37 HOH N O 1 HETATM 6554 O O . HOH N 8 . ? 77.253 17.500 136.014 1.00 50.93 ? 38 HOH N O 1 HETATM 6555 O O . HOH N 8 . ? 71.040 -2.834 117.173 1.00 24.20 ? 39 HOH N O 1 HETATM 6556 O O . HOH N 8 . ? 72.564 -2.133 119.207 1.00 13.27 ? 40 HOH N O 1 HETATM 6557 O O . HOH N 8 . ? 58.457 8.958 120.988 1.00 28.93 ? 41 HOH N O 1 HETATM 6558 O O . HOH N 8 . ? 59.000 -2.468 128.361 1.00 36.32 ? 42 HOH N O 1 HETATM 6559 O O . HOH N 8 . ? 63.547 -4.982 127.848 1.00 16.49 ? 43 HOH N O 1 HETATM 6560 O O . HOH N 8 . ? 56.849 -4.045 134.869 1.00 31.71 ? 44 HOH N O 1 HETATM 6561 O O . HOH N 8 . ? 60.028 -5.147 136.504 1.00 28.98 ? 45 HOH N O 1 HETATM 6562 O O . HOH N 8 . ? 53.938 -8.213 131.112 1.00 40.94 ? 46 HOH N O 1 HETATM 6563 O O . HOH N 8 . ? 51.277 -7.126 132.379 1.00 14.87 ? 47 HOH N O 1 HETATM 6564 O O . HOH N 8 . ? 39.898 12.551 133.574 1.00 67.23 ? 48 HOH N O 1 HETATM 6565 O O . HOH N 8 . ? 42.687 11.724 134.155 1.00 33.14 ? 49 HOH N O 1 HETATM 6566 O O . HOH N 8 . ? 69.513 10.634 127.265 1.00 35.84 ? 50 HOH N O 1 HETATM 6567 O O . HOH N 8 . ? 83.623 1.949 118.828 1.00 38.65 ? 51 HOH N O 1 HETATM 6568 O O . HOH N 8 . ? 68.405 5.224 110.796 1.00 28.27 ? 52 HOH N O 1 HETATM 6569 O O . HOH N 8 . ? 62.169 11.222 148.110 1.00 4.57 ? 53 HOH N O 1 HETATM 6570 O O . HOH N 8 . ? 62.030 13.308 146.283 1.00 24.13 ? 54 HOH N O 1 HETATM 6571 O O . HOH N 8 . ? 62.715 12.663 150.192 1.00 36.24 ? 55 HOH N O 1 HETATM 6572 O O . HOH N 8 . ? 55.718 11.798 143.601 1.00 37.34 ? 56 HOH N O 1 HETATM 6573 O O . HOH N 8 . ? 61.306 16.514 143.326 1.00 26.24 ? 57 HOH N O 1 HETATM 6574 O O . HOH N 8 . ? 54.569 10.825 156.786 1.00 23.57 ? 58 HOH N O 1 HETATM 6575 O O . HOH N 8 . ? 51.131 10.559 136.810 1.00 31.98 ? 59 HOH N O 1 HETATM 6576 O O . HOH N 8 . ? 58.107 20.172 128.974 1.00 24.02 ? 60 HOH N O 1 HETATM 6577 O O . HOH N 8 . ? 55.471 21.396 140.419 1.00 45.28 ? 61 HOH N O 1 HETATM 6578 O O . HOH N 8 . ? 49.544 26.286 132.604 1.00 27.14 ? 62 HOH N O 1 HETATM 6579 O O . HOH N 8 . ? 48.352 28.591 133.043 1.00 48.98 ? 63 HOH N O 1 HETATM 6580 O O . HOH N 8 . ? 56.145 22.723 129.733 1.00 12.02 ? 64 HOH N O 1 HETATM 6581 O O . HOH N 8 . ? 55.486 23.935 127.170 1.00 32.51 ? 65 HOH N O 1 HETATM 6582 O O . HOH N 8 . ? 59.886 16.985 118.846 1.00 43.42 ? 66 HOH N O 1 HETATM 6583 O O . HOH N 8 . ? 62.334 34.003 129.162 1.00 30.39 ? 67 HOH N O 1 HETATM 6584 O O . HOH N 8 . ? 70.589 30.130 130.828 1.00 36.56 ? 68 HOH N O 1 HETATM 6585 O O . HOH N 8 . ? 61.689 14.966 116.478 1.00 43.74 ? 69 HOH N O 1 HETATM 6586 O O . HOH N 8 . ? 69.042 34.720 134.315 1.00 23.86 ? 70 HOH N O 1 HETATM 6587 O O . HOH N 8 . ? 61.225 7.010 121.993 1.00 45.29 ? 71 HOH N O 1 HETATM 6588 O O . HOH N 8 . ? 48.040 31.578 119.163 1.00 0.00 ? 72 HOH N O 1 HETATM 6589 O O . HOH O 8 . ? 41.437 21.004 110.405 1.00 21.55 ? 215 HOH L O 1 HETATM 6590 O O . HOH O 8 . ? 29.310 50.852 83.091 1.00 16.32 ? 216 HOH L O 1 HETATM 6591 O O . HOH P 8 . ? 67.179 34.191 103.340 1.00 43.88 ? 228 HOH H O 1 HETATM 6592 O O . HOH P 8 . ? 49.708 35.133 110.872 1.00 35.51 ? 229 HOH H O 1 HETATM 6593 O O . HOH P 8 . ? 56.721 38.319 76.237 1.00 49.30 ? 230 HOH H O 1 HETATM 6594 O O . HOH P 8 . ? 48.560 42.580 123.988 1.00 39.89 ? 231 HOH H O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ILE 1 81 81 ILE ILE N . n A 1 2 ARG 2 82 82 ARG ARG N . n A 1 3 ASP 3 83 83 ASP ASP N . n A 1 4 PHE 4 84 84 PHE PHE N . n A 1 5 ASN 5 85 85 ASN ASN N . n A 1 6 ASN 6 86 86 ASN ASN N . n A 1 7 LEU 7 87 87 LEU LEU N . n A 1 8 THR 8 88 88 THR THR N . n A 1 9 LYS 9 89 89 LYS LYS N . n A 1 10 GLY 10 90 90 GLY GLY N . n A 1 11 LEU 11 91 91 LEU LEU N . n A 1 12 CYS 12 92 92 CYS CYS N . n A 1 13 THR 13 93 93 THR THR N . n A 1 14 ILE 14 94 94 ILE ILE N . n A 1 15 ASN 15 95 95 ASN ASN N . n A 1 16 SER 16 96 96 SER SER N . n A 1 17 TRP 17 97 97 TRP TRP N . n A 1 18 HIS 18 98 98 HIS HIS N . n A 1 19 ILE 19 99 99 ILE ILE N . n A 1 20 TYR 20 100 100 TYR TYR N . n A 1 21 GLY 21 101 101 GLY GLY N . n A 1 22 LYS 22 102 102 LYS LYS N . n A 1 23 ASP 23 103 103 ASP ASP N . n A 1 24 ASN 24 104 104 ASN ASN N . n A 1 25 ALA 25 105 105 ALA ALA N . n A 1 26 VAL 26 106 106 VAL VAL N . n A 1 27 ARG 27 107 107 ARG ARG N . n A 1 28 ILE 28 108 108 ILE ILE N . n A 1 29 GLY 29 109 109 GLY GLY N . n A 1 30 GLU 30 110 110 GLU GLU N . n A 1 31 ASP 31 111 111 ASP ASP N . n A 1 32 SER 32 112 112 SER SER N . n A 1 33 ASP 33 113 113 ASP ASP N . n A 1 34 VAL 34 114 114 VAL VAL N . n A 1 35 LEU 35 115 115 LEU LEU N . n A 1 36 VAL 36 116 116 VAL VAL N . n A 1 37 THR 37 117 117 THR THR N . n A 1 38 ARG 38 118 118 ARG ARG N . n A 1 39 GLU 39 119 119 GLU GLU N . n A 1 40 PRO 40 120 120 PRO PRO N . n A 1 41 TYR 41 121 121 TYR TYR N . n A 1 42 VAL 42 122 122 VAL VAL N . n A 1 43 SER 43 123 123 SER SER N . n A 1 44 CYS 44 124 124 CYS CYS N . n A 1 45 ASP 45 125 125 ASP ASP N . n A 1 46 PRO 46 126 126 PRO PRO N . n A 1 47 ASP 47 127 127 ASP ASP N . n A 1 48 GLU 48 128 128 GLU GLU N . n A 1 49 CYS 49 129 129 CYS CYS N . n A 1 50 ARG 50 130 130 ARG ARG N . n A 1 51 PHE 51 131 131 PHE PHE N . n A 1 52 TYR 52 132 132 TYR TYR N . n A 1 53 ALA 53 133 133 ALA ALA N . n A 1 54 LEU 54 134 134 LEU LEU N . n A 1 55 SER 55 135 135 SER SER N . n A 1 56 GLN 56 136 136 GLN GLN N . n A 1 57 GLY 57 137 137 GLY GLY N . n A 1 58 THR 58 138 138 THR THR N . n A 1 59 THR 59 139 139 THR THR N . n A 1 60 ILE 60 140 140 ILE ILE N . n A 1 61 ARG 61 141 141 ARG ARG N . n A 1 62 GLY 62 142 142 GLY GLY N . n A 1 63 LYS 63 143 143 LYS LYS N . n A 1 64 HIS 64 144 144 HIS HIS N . n A 1 65 SER 65 145 145 SER SER N . n A 1 66 ASN 66 146 146 ASN ASN N . n A 1 67 GLY 67 147 147 GLY GLY N . n A 1 68 THR 68 148 148 THR THR N . n A 1 69 ILE 69 149 149 ILE ILE N . n A 1 70 HIS 70 150 150 HIS HIS N . n A 1 71 ASP 71 151 151 ASP ASP N . n A 1 72 ARG 72 152 152 ARG ARG N . n A 1 73 SER 73 153 153 SER SER N . n A 1 74 GLN 74 154 154 GLN GLN N . n A 1 75 TYR 75 155 155 TYR TYR N . n A 1 76 ARG 76 156 156 ARG ARG N . n A 1 77 ALA 77 157 157 ALA ALA N . n A 1 78 LEU 78 158 158 LEU LEU N . n A 1 79 ILE 79 159 159 ILE ILE N . n A 1 80 SER 80 160 160 SER SER N . n A 1 81 TRP 81 161 161 TRP TRP N . n A 1 82 PRO 82 162 162 PRO PRO N . n A 1 83 LEU 83 163 163 LEU LEU N . n A 1 84 SER 84 164 164 SER SER N . n A 1 85 SER 85 165 165 SER SER N . n A 1 86 PRO 86 166 166 PRO PRO N . n A 1 87 PRO 87 167 167 PRO PRO N . n A 1 88 THR 88 168 168 THR THR N . n A 1 89 VAL 89 169 169 VAL VAL N . n A 1 90 TYR 90 169 169 TYR TYR N A n A 1 91 ASN 91 170 170 ASN ASN N . n A 1 92 SER 92 171 171 SER SER N . n A 1 93 ARG 93 172 172 ARG ARG N . n A 1 94 VAL 94 173 173 VAL VAL N . n A 1 95 GLU 95 174 174 GLU GLU N . n A 1 96 CYS 96 175 175 CYS CYS N . n A 1 97 ILE 97 176 176 ILE ILE N . n A 1 98 GLY 98 177 177 GLY GLY N . n A 1 99 TRP 99 178 178 TRP TRP N . n A 1 100 SER 100 179 179 SER SER N . n A 1 101 SER 101 180 180 SER SER N . n A 1 102 THR 102 181 181 THR THR N . n A 1 103 SER 103 182 182 SER SER N . n A 1 104 CYS 104 183 183 CYS CYS N . n A 1 105 HIS 105 184 184 HIS HIS N . n A 1 106 ASP 106 185 185 ASP ASP N . n A 1 107 GLY 107 186 186 GLY GLY N . n A 1 108 LYS 108 187 187 LYS LYS N . n A 1 109 THR 109 188 188 THR THR N . n A 1 110 ARG 110 189 189 ARG ARG N . n A 1 111 MET 111 190 190 MET MET N . n A 1 112 SER 112 191 191 SER SER N . n A 1 113 ILE 113 192 192 ILE ILE N . n A 1 114 CYS 114 193 193 CYS CYS N . n A 1 115 ILE 115 194 194 ILE ILE N . n A 1 116 SER 116 195 195 SER SER N . n A 1 117 GLY 117 196 196 GLY GLY N . n A 1 118 PRO 118 197 197 PRO PRO N . n A 1 119 ASN 119 198 198 ASN ASN N . n A 1 120 ASN 120 199 199 ASN ASN N . n A 1 121 ASN 121 200 200 ASN ASN N . n A 1 122 ALA 122 201 201 ALA ALA N . n A 1 123 SER 123 202 202 SER SER N . n A 1 124 ALA 124 203 203 ALA ALA N . n A 1 125 VAL 125 204 204 VAL VAL N . n A 1 126 ILE 126 205 205 ILE ILE N . n A 1 127 TRP 127 206 206 TRP TRP N . n A 1 128 TYR 128 207 207 TYR TYR N . n A 1 129 ASN 129 208 208 ASN ASN N . n A 1 130 ARG 130 209 209 ARG ARG N . n A 1 131 ARG 131 210 210 ARG ARG N . n A 1 132 PRO 132 211 211 PRO PRO N . n A 1 133 VAL 133 212 212 VAL VAL N . n A 1 134 THR 134 213 213 THR THR N . n A 1 135 GLU 135 214 214 GLU GLU N . n A 1 136 ILE 136 215 215 ILE ILE N . n A 1 137 ASN 137 216 216 ASN ASN N . n A 1 138 THR 138 217 217 THR THR N . n A 1 139 TRP 139 218 218 TRP TRP N . n A 1 140 ALA 140 219 219 ALA ALA N . n A 1 141 ARG 141 220 220 ARG ARG N . n A 1 142 ASN 142 221 221 ASN ASN N . n A 1 143 ILE 143 222 222 ILE ILE N . n A 1 144 LEU 144 223 223 LEU LEU N . n A 1 145 ARG 145 224 224 ARG ARG N . n A 1 146 THR 146 225 225 THR THR N . n A 1 147 GLN 147 226 226 GLN GLN N . n A 1 148 GLU 148 227 227 GLU GLU N . n A 1 149 SER 149 228 228 SER SER N . n A 1 150 GLU 150 229 229 GLU GLU N . n A 1 151 CYS 151 230 230 CYS CYS N . n A 1 152 VAL 152 231 231 VAL VAL N . n A 1 153 CYS 153 232 232 CYS CYS N . n A 1 154 HIS 154 233 233 HIS HIS N . n A 1 155 ASN 155 234 234 ASN ASN N . n A 1 156 GLY 156 235 235 GLY GLY N . n A 1 157 VAL 157 236 236 VAL VAL N . n A 1 158 CYS 158 237 237 CYS CYS N . n A 1 159 PRO 159 238 238 PRO PRO N . n A 1 160 VAL 160 239 239 VAL VAL N . n A 1 161 VAL 161 240 240 VAL VAL N . n A 1 162 PHE 162 241 241 PHE PHE N . n A 1 163 THR 163 242 242 THR THR N . n A 1 164 ASP 164 243 243 ASP ASP N . n A 1 165 GLY 165 244 244 GLY GLY N . n A 1 166 SER 166 245 245 SER SER N . n A 1 167 ALA 167 246 246 ALA ALA N . n A 1 168 THR 168 247 247 THR THR N . n A 1 169 GLY 169 248 248 GLY GLY N . n A 1 170 PRO 170 249 249 PRO PRO N . n A 1 171 ALA 171 250 250 ALA ALA N . n A 1 172 GLU 172 251 251 GLU GLU N . n A 1 173 THR 173 252 252 THR THR N . n A 1 174 ARG 174 253 253 ARG ARG N . n A 1 175 ILE 175 254 254 ILE ILE N . n A 1 176 TYR 176 255 255 TYR TYR N . n A 1 177 TYR 177 256 256 TYR TYR N . n A 1 178 PHE 178 257 257 PHE PHE N . n A 1 179 LYS 179 258 258 LYS LYS N . n A 1 180 GLU 180 259 259 GLU GLU N . n A 1 181 GLY 181 260 260 GLY GLY N . n A 1 182 LYS 182 261 261 LYS LYS N . n A 1 183 ILE 183 262 262 ILE ILE N . n A 1 184 LEU 184 263 263 LEU LEU N . n A 1 185 LYS 185 264 264 LYS LYS N . n A 1 186 TRP 186 265 265 TRP TRP N . n A 1 187 GLU 187 266 266 GLU GLU N . n A 1 188 PRO 188 267 267 PRO PRO N . n A 1 189 LEU 189 268 268 LEU LEU N . n A 1 190 ALA 190 269 269 ALA ALA N . n A 1 191 GLY 191 270 270 GLY GLY N . n A 1 192 THR 192 271 271 THR THR N . n A 1 193 ALA 193 272 272 ALA ALA N . n A 1 194 LYS 194 273 273 LYS LYS N . n A 1 195 HIS 195 274 274 HIS HIS N . n A 1 196 ILE 196 275 275 ILE ILE N . n A 1 197 GLU 197 276 276 GLU GLU N . n A 1 198 GLU 198 277 277 GLU GLU N . n A 1 199 CYS 199 278 278 CYS CYS N . n A 1 200 SER 200 279 279 SER SER N . n A 1 201 CYS 201 280 280 CYS CYS N . n A 1 202 TYR 202 281 281 TYR TYR N . n A 1 203 GLY 203 282 282 GLY GLY N . n A 1 204 GLU 204 283 283 GLU GLU N . n A 1 205 ARG 205 284 284 ARG ARG N . n A 1 206 ALA 206 285 285 ALA ALA N . n A 1 207 GLU 207 286 286 GLU GLU N . n A 1 208 ILE 208 287 287 ILE ILE N . n A 1 209 THR 209 288 288 THR THR N . n A 1 210 CYS 210 289 289 CYS CYS N . n A 1 211 THR 211 290 290 THR THR N . n A 1 212 CYS 212 291 291 CYS CYS N . n A 1 213 ARG 213 292 292 ARG ARG N . n A 1 214 ASP 214 293 293 ASP ASP N . n A 1 215 ASN 215 294 294 ASN ASN N . n A 1 216 TRP 216 295 295 TRP TRP N . n A 1 217 GLN 217 296 296 GLN GLN N . n A 1 218 GLY 218 297 297 GLY GLY N . n A 1 219 SER 219 298 298 SER SER N . n A 1 220 ASN 220 299 299 ASN ASN N . n A 1 221 ARG 221 300 300 ARG ARG N . n A 1 222 PRO 222 301 301 PRO PRO N . n A 1 223 VAL 223 302 302 VAL VAL N . n A 1 224 ILE 224 303 303 ILE ILE N . n A 1 225 ARG 225 304 304 ARG ARG N . n A 1 226 ILE 226 305 305 ILE ILE N . n A 1 227 ASP 227 306 306 ASP ASP N . n A 1 228 PRO 228 307 307 PRO PRO N . n A 1 229 VAL 229 308 308 VAL VAL N . n A 1 230 ALA 230 309 309 ALA ALA N . n A 1 231 MET 231 310 310 MET MET N . n A 1 232 THR 232 311 311 THR THR N . n A 1 233 HIS 233 312 312 HIS HIS N . n A 1 234 THR 234 313 313 THR THR N . n A 1 235 SER 235 314 314 SER SER N . n A 1 236 GLN 236 315 315 GLN GLN N . n A 1 237 TYR 237 316 316 TYR TYR N . n A 1 238 ILE 238 317 317 ILE ILE N . n A 1 239 CYS 239 318 318 CYS CYS N . n A 1 240 SER 240 319 319 SER SER N . n A 1 241 PRO 241 320 320 PRO PRO N . n A 1 242 VAL 242 321 321 VAL VAL N . n A 1 243 LEU 243 322 322 LEU LEU N . n A 1 244 THR 244 323 323 THR THR N . n A 1 245 ASP 245 324 324 ASP ASP N . n A 1 246 ASN 246 325 325 ASN ASN N . n A 1 247 PRO 247 326 326 PRO PRO N . n A 1 248 ARG 248 327 327 ARG ARG N . n A 1 249 PRO 249 328 328 PRO PRO N . n A 1 250 ASP 250 329 329 ASP ASP N . n A 1 251 ASP 251 330 330 ASP ASP N . n A 1 252 PRO 252 331 331 PRO PRO N . n A 1 253 THR 253 332 332 THR THR N . n A 1 254 VAL 254 333 333 VAL VAL N . n A 1 255 GLY 255 335 335 GLY GLY N . n A 1 256 LYS 256 336 336 LYS LYS N . n A 1 257 CYS 257 337 337 CYS CYS N . n A 1 258 ASN 258 338 338 ASN ASN N . n A 1 259 ASP 259 339 339 ASP ASP N . n A 1 260 PRO 260 340 340 PRO PRO N . n A 1 261 TYR 261 341 341 TYR TYR N . n A 1 262 PRO 262 342 342 PRO PRO N . n A 1 263 GLY 263 343 343 GLY GLY N . n A 1 264 ASN 264 344 344 ASN ASN N . n A 1 265 ASN 265 345 345 ASN ASN N . n A 1 266 ASN 266 346 346 ASN ASN N . n A 1 267 ASN 267 347 347 ASN ASN N . n A 1 268 GLY 268 348 348 GLY GLY N . n A 1 269 VAL 269 349 349 VAL VAL N . n A 1 270 LYS 270 350 350 LYS LYS N . n A 1 271 GLY 271 351 351 GLY GLY N . n A 1 272 PHE 272 352 352 PHE PHE N . n A 1 273 SER 273 353 353 SER SER N . n A 1 274 TYR 274 354 354 TYR TYR N . n A 1 275 LEU 275 355 355 LEU LEU N . n A 1 276 ASP 276 356 356 ASP ASP N . n A 1 277 GLY 277 357 357 GLY GLY N . n A 1 278 VAL 278 358 358 VAL VAL N . n A 1 279 ASN 279 359 359 ASN ASN N . n A 1 280 THR 280 360 360 THR THR N . n A 1 281 TRP 281 361 361 TRP TRP N . n A 1 282 LEU 282 362 362 LEU LEU N . n A 1 283 GLY 283 363 363 GLY GLY N . n A 1 284 ARG 284 364 364 ARG ARG N . n A 1 285 THR 285 365 365 THR THR N . n A 1 286 ILE 286 366 366 ILE ILE N . n A 1 287 SER 287 367 367 SER SER N . n A 1 288 ILE 288 368 368 ILE ILE N . n A 1 289 ALA 289 369 369 ALA ALA N . n A 1 290 SER 290 370 370 SER SER N . n A 1 291 ARG 291 371 371 ARG ARG N . n A 1 292 SER 292 372 372 SER SER N . n A 1 293 GLY 293 373 373 GLY GLY N . n A 1 294 TYR 294 374 374 TYR TYR N . n A 1 295 GLU 295 375 375 GLU GLU N . n A 1 296 MET 296 376 376 MET MET N . n A 1 297 LEU 297 377 377 LEU LEU N . n A 1 298 LYS 298 378 378 LYS LYS N . n A 1 299 VAL 299 379 379 VAL VAL N . n A 1 300 PRO 300 380 380 PRO PRO N . n A 1 301 ASN 301 381 381 ASN ASN N . n A 1 302 ALA 302 382 382 ALA ALA N . n A 1 303 LEU 303 383 383 LEU LEU N . n A 1 304 THR 304 384 384 THR THR N . n A 1 305 ASP 305 385 385 ASP ASP N . n A 1 306 ASP 306 386 386 ASP ASP N . n A 1 307 LYS 307 387 387 LYS LYS N . n A 1 308 SER 308 388 388 SER SER N . n A 1 309 LYS 309 389 389 LYS LYS N . n A 1 310 PRO 310 390 390 PRO PRO N . n A 1 311 THR 311 391 391 THR THR N . n A 1 312 GLN 312 392 392 GLN GLN N . n A 1 313 GLY 313 394 394 GLY GLY N . n A 1 314 GLN 314 395 395 GLN GLN N . n A 1 315 THR 315 396 396 THR THR N . n A 1 316 ILE 316 397 397 ILE ILE N . n A 1 317 VAL 317 398 398 VAL VAL N . n A 1 318 LEU 318 399 399 LEU LEU N . n A 1 319 ASN 319 400 400 ASN ASN N . n A 1 320 THR 320 401 401 THR THR N . n A 1 321 ASP 321 402 402 ASP ASP N . n A 1 322 TRP 322 403 403 TRP TRP N . n A 1 323 SER 323 404 404 SER SER N . n A 1 324 GLY 324 405 405 GLY GLY N . n A 1 325 TYR 325 406 406 TYR TYR N . n A 1 326 SER 326 407 407 SER SER N . n A 1 327 GLY 327 408 408 GLY GLY N . n A 1 328 SER 328 409 409 SER SER N . n A 1 329 PHE 329 410 410 PHE PHE N . n A 1 330 MET 330 411 411 MET MET N . n A 1 331 ASP 331 412 412 ASP ASP N . n A 1 332 TYR 332 412 412 TYR TYR N A n A 1 333 TRP 333 412 412 TRP TRP N B n A 1 334 ALA 334 413 413 ALA ALA N . n A 1 335 GLU 335 414 414 GLU GLU N . n A 1 336 GLY 336 415 415 GLY GLY N . n A 1 337 GLU 337 416 416 GLU GLU N . n A 1 338 CYS 338 417 417 CYS CYS N . n A 1 339 TYR 339 418 418 TYR TYR N . n A 1 340 ARG 340 419 419 ARG ARG N . n A 1 341 ALA 341 420 420 ALA ALA N . n A 1 342 CYS 342 421 421 CYS CYS N . n A 1 343 PHE 343 422 422 PHE PHE N . n A 1 344 TYR 344 423 423 TYR TYR N . n A 1 345 VAL 345 424 424 VAL VAL N . n A 1 346 GLU 346 425 425 GLU GLU N . n A 1 347 LEU 347 426 426 LEU LEU N . n A 1 348 ILE 348 427 427 ILE ILE N . n A 1 349 ARG 349 428 428 ARG ARG N . n A 1 350 GLY 350 429 429 GLY GLY N . n A 1 351 ARG 351 430 430 ARG ARG N . n A 1 352 PRO 352 431 431 PRO PRO N . n A 1 353 LYS 353 432 432 LYS LYS N . n A 1 354 GLU 354 433 433 GLU GLU N . n A 1 355 ASP 355 434 434 ASP ASP N . n A 1 356 LYS 356 435 435 LYS LYS N . n A 1 357 VAL 357 436 436 VAL VAL N . n A 1 358 TRP 358 437 437 TRP TRP N . n A 1 359 TRP 359 438 438 TRP TRP N . n A 1 360 THR 360 439 439 THR THR N . n A 1 361 SER 361 440 440 SER SER N . n A 1 362 ASN 362 441 441 ASN ASN N . n A 1 363 SER 363 442 442 SER SER N . n A 1 364 ILE 364 443 443 ILE ILE N . n A 1 365 VAL 365 444 444 VAL VAL N . n A 1 366 SER 366 445 445 SER SER N . n A 1 367 MET 367 446 446 MET MET N . n A 1 368 CYS 368 447 447 CYS CYS N . n A 1 369 SER 369 448 448 SER SER N . n A 1 370 SER 370 449 449 SER SER N . n A 1 371 THR 371 450 450 THR THR N . n A 1 372 GLU 372 451 451 GLU GLU N . n A 1 373 PHE 373 452 452 PHE PHE N . n A 1 374 LEU 374 453 453 LEU LEU N . n A 1 375 GLY 375 454 454 GLY GLY N . n A 1 376 GLN 376 455 455 GLN GLN N . n A 1 377 TRP 377 456 456 TRP TRP N . n A 1 378 ASP 378 457 457 ASP ASP N . n A 1 379 TRP 379 458 458 TRP TRP N . n A 1 380 PRO 380 459 459 PRO PRO N . n A 1 381 ASP 381 460 460 ASP ASP N . n A 1 382 GLY 382 461 461 GLY GLY N . n A 1 383 ALA 383 462 462 ALA ALA N . n A 1 384 LYS 384 463 463 LYS LYS N . n A 1 385 ILE 385 464 464 ILE ILE N . n A 1 386 GLU 386 465 465 GLU GLU N . n A 1 387 TYR 387 466 466 TYR TYR N . n A 1 388 PHE 388 467 467 PHE PHE N . n A 1 389 LEU 389 468 468 LEU LEU N . n B 2 1 ASP 1 1 1 ASP ASP L . n B 2 2 ILE 2 2 2 ILE ILE L . n B 2 3 VAL 3 3 3 VAL VAL L . n B 2 4 MET 4 4 4 MET MET L . n B 2 5 THR 5 5 5 THR THR L . n B 2 6 GLN 6 6 6 GLN GLN L . n B 2 7 SER 7 7 7 SER SER L . n B 2 8 PRO 8 8 8 PRO PRO L . n B 2 9 LYS 9 9 9 LYS LYS L . n B 2 10 PHE 10 10 10 PHE PHE L . n B 2 11 MET 11 11 11 MET MET L . n B 2 12 SER 12 12 12 SER SER L . n B 2 13 THR 13 13 13 THR THR L . n B 2 14 SER 14 14 14 SER SER L . n B 2 15 VAL 15 15 15 VAL VAL L . n B 2 16 GLY 16 16 16 GLY GLY L . n B 2 17 ASP 17 17 17 ASP ASP L . n B 2 18 ARG 18 18 18 ARG ARG L . n B 2 19 VAL 19 19 19 VAL VAL L . n B 2 20 THR 20 20 20 THR THR L . n B 2 21 ILE 21 21 21 ILE ILE L . n B 2 22 THR 22 22 22 THR THR L . n B 2 23 CYS 23 23 23 CYS CYS L . n B 2 24 LYS 24 24 24 LYS LYS L . n B 2 25 ALA 25 25 25 ALA ALA L . n B 2 26 SER 26 26 26 SER SER L . n B 2 27 GLN 27 27 27 GLN GLN L . n B 2 28 ASP 28 28 28 ASP ASP L . n B 2 29 VAL 29 29 29 VAL VAL L . n B 2 30 SER 30 30 30 SER SER L . n B 2 31 THR 31 31 31 THR THR L . n B 2 32 ALA 32 32 32 ALA ALA L . n B 2 33 VAL 33 33 33 VAL VAL L . n B 2 34 VAL 34 34 34 VAL VAL L . n B 2 35 TRP 35 35 35 TRP TRP L . n B 2 36 TYR 36 36 36 TYR TYR L . n B 2 37 GLN 37 37 37 GLN GLN L . n B 2 38 GLN 38 38 38 GLN GLN L . n B 2 39 LYS 39 39 39 LYS LYS L . n B 2 40 PRO 40 40 40 PRO PRO L . n B 2 41 GLY 41 41 41 GLY GLY L . n B 2 42 GLN 42 42 42 GLN GLN L . n B 2 43 SER 43 43 43 SER SER L . n B 2 44 PRO 44 44 44 PRO PRO L . n B 2 45 LYS 45 45 45 LYS LYS L . n B 2 46 LEU 46 46 46 LEU LEU L . n B 2 47 LEU 47 47 47 LEU LEU L . n B 2 48 ILE 48 48 48 ILE ILE L . n B 2 49 TYR 49 49 49 TYR TYR L . n B 2 50 TRP 50 50 50 TRP TRP L . n B 2 51 ALA 51 51 51 ALA ALA L . n B 2 52 SER 52 52 52 SER SER L . n B 2 53 THR 53 53 53 THR THR L . n B 2 54 ARG 54 54 54 ARG ARG L . n B 2 55 HIS 55 55 55 HIS HIS L . n B 2 56 ILE 56 56 56 ILE ILE L . n B 2 57 GLY 57 57 57 GLY GLY L . n B 2 58 VAL 58 58 58 VAL VAL L . n B 2 59 PRO 59 59 59 PRO PRO L . n B 2 60 ASP 60 60 60 ASP ASP L . n B 2 61 ARG 61 61 61 ARG ARG L . n B 2 62 PHE 62 62 62 PHE PHE L . n B 2 63 ALA 63 63 63 ALA ALA L . n B 2 64 GLY 64 64 64 GLY GLY L . n B 2 65 SER 65 65 65 SER SER L . n B 2 66 GLY 66 66 66 GLY GLY L . n B 2 67 SER 67 67 67 SER SER L . n B 2 68 GLY 68 68 68 GLY GLY L . n B 2 69 THR 69 69 69 THR THR L . n B 2 70 ASP 70 70 70 ASP ASP L . n B 2 71 TYR 71 71 71 TYR TYR L . n B 2 72 THR 72 72 72 THR THR L . n B 2 73 LEU 73 73 73 LEU LEU L . n B 2 74 THR 74 74 74 THR THR L . n B 2 75 ILE 75 75 75 ILE ILE L . n B 2 76 SER 76 76 76 SER SER L . n B 2 77 SER 77 77 77 SER SER L . n B 2 78 VAL 78 78 78 VAL VAL L . n B 2 79 GLN 79 79 79 GLN GLN L . n B 2 80 ALA 80 80 80 ALA ALA L . n B 2 81 GLU 81 81 81 GLU GLU L . n B 2 82 ASP 82 82 82 ASP ASP L . n B 2 83 LEU 83 83 83 LEU LEU L . n B 2 84 ALA 84 84 84 ALA ALA L . n B 2 85 LEU 85 85 85 LEU LEU L . n B 2 86 TYR 86 86 86 TYR TYR L . n B 2 87 TYR 87 87 87 TYR TYR L . n B 2 88 CYS 88 88 88 CYS CYS L . n B 2 89 GLN 89 89 89 GLN GLN L . n B 2 90 GLN 90 90 90 GLN GLN L . n B 2 91 HIS 91 91 91 HIS HIS L . n B 2 92 TYR 92 92 92 TYR TYR L . n B 2 93 SER 93 93 93 SER SER L . n B 2 94 PRO 94 94 94 PRO PRO L . n B 2 95 PRO 95 95 95 PRO PRO L . n B 2 96 TRP 96 96 96 TRP TRP L . n B 2 97 THR 97 97 97 THR THR L . n B 2 98 PHE 98 98 98 PHE PHE L . n B 2 99 GLY 99 99 99 GLY GLY L . n B 2 100 GLY 100 100 100 GLY GLY L . n B 2 101 GLY 101 101 101 GLY GLY L . n B 2 102 THR 102 102 102 THR THR L . n B 2 103 LYS 103 103 103 LYS LYS L . n B 2 104 LEU 104 104 104 LEU LEU L . n B 2 105 GLU 105 105 105 GLU GLU L . n B 2 106 ILE 106 106 106 ILE ILE L . n B 2 107 LYS 107 107 107 LYS LYS L . n B 2 108 ARG 108 108 108 ARG ARG L . n B 2 109 ALA 109 109 109 ALA ALA L . n B 2 110 ASP 110 110 110 ASP ASP L . n B 2 111 ALA 111 111 111 ALA ALA L . n B 2 112 ALA 112 112 112 ALA ALA L . n B 2 113 PRO 113 113 113 PRO PRO L . n B 2 114 THR 114 114 114 THR THR L . n B 2 115 VAL 115 115 115 VAL VAL L . n B 2 116 SER 116 116 116 SER SER L . n B 2 117 ILE 117 117 117 ILE ILE L . n B 2 118 PHE 118 118 118 PHE PHE L . n B 2 119 PRO 119 119 119 PRO PRO L . n B 2 120 PRO 120 120 120 PRO PRO L . n B 2 121 SER 121 121 121 SER SER L . n B 2 122 SER 122 122 122 SER SER L . n B 2 123 GLU 123 123 123 GLU GLU L . n B 2 124 GLN 124 124 124 GLN GLN L . n B 2 125 LEU 125 125 125 LEU LEU L . n B 2 126 THR 126 126 126 THR THR L . n B 2 127 SER 127 127 127 SER SER L . n B 2 128 GLY 128 128 128 GLY GLY L . n B 2 129 GLY 129 129 129 GLY GLY L . n B 2 130 ALA 130 130 130 ALA ALA L . n B 2 131 SER 131 131 131 SER SER L . n B 2 132 VAL 132 132 132 VAL VAL L . n B 2 133 VAL 133 133 133 VAL VAL L . n B 2 134 CYS 134 134 134 CYS CYS L . n B 2 135 PHE 135 135 135 PHE PHE L . n B 2 136 LEU 136 136 136 LEU LEU L . n B 2 137 ASN 137 137 137 ASN ASN L . n B 2 138 ASN 138 138 138 ASN ASN L . n B 2 139 PHE 139 139 139 PHE PHE L . n B 2 140 TYR 140 140 140 TYR TYR L . n B 2 141 PRO 141 141 141 PRO PRO L . n B 2 142 LYS 142 142 142 LYS LYS L . n B 2 143 ASP 143 143 143 ASP ASP L . n B 2 144 ILE 144 144 144 ILE ILE L . n B 2 145 ASN 145 145 145 ASN ASN L . n B 2 146 VAL 146 146 146 VAL VAL L . n B 2 147 LYS 147 147 147 LYS LYS L . n B 2 148 TRP 148 148 148 TRP TRP L . n B 2 149 LYS 149 149 149 LYS LYS L . n B 2 150 ILE 150 150 150 ILE ILE L . n B 2 151 ASP 151 151 151 ASP ASP L . n B 2 152 GLY 152 152 152 GLY GLY L . n B 2 153 SER 153 153 153 SER SER L . n B 2 154 GLU 154 154 154 GLU GLU L . n B 2 155 ARG 155 155 155 ARG ARG L . n B 2 156 GLN 156 156 156 GLN GLN L . n B 2 157 ASN 157 157 157 ASN ASN L . n B 2 158 GLY 158 158 158 GLY GLY L . n B 2 159 VAL 159 159 159 VAL VAL L . n B 2 160 LEU 160 160 160 LEU LEU L . n B 2 161 ASN 161 161 161 ASN ASN L . n B 2 162 SER 162 162 162 SER SER L . n B 2 163 TRP 163 163 163 TRP TRP L . n B 2 164 THR 164 164 164 THR THR L . n B 2 165 ASP 165 165 165 ASP ASP L . n B 2 166 GLN 166 166 166 GLN GLN L . n B 2 167 ASP 167 167 167 ASP ASP L . n B 2 168 SER 168 168 168 SER SER L . n B 2 169 LYS 169 169 169 LYS LYS L . n B 2 170 ASP 170 170 170 ASP ASP L . n B 2 171 SER 171 171 171 SER SER L . n B 2 172 THR 172 172 172 THR THR L . n B 2 173 TYR 173 173 173 TYR TYR L . n B 2 174 SER 174 174 174 SER SER L . n B 2 175 MET 175 175 175 MET MET L . n B 2 176 SER 176 176 176 SER SER L . n B 2 177 SER 177 177 177 SER SER L . n B 2 178 THR 178 178 178 THR THR L . n B 2 179 LEU 179 179 179 LEU LEU L . n B 2 180 THR 180 180 180 THR THR L . n B 2 181 LEU 181 181 181 LEU LEU L . n B 2 182 THR 182 182 182 THR THR L . n B 2 183 LYS 183 183 183 LYS LYS L . n B 2 184 ASP 184 184 184 ASP ASP L . n B 2 185 GLU 185 185 185 GLU GLU L . n B 2 186 TYR 186 186 186 TYR TYR L . n B 2 187 GLU 187 187 187 GLU GLU L . n B 2 188 ARG 188 188 188 ARG ARG L . n B 2 189 HIS 189 189 189 HIS HIS L . n B 2 190 ASN 190 190 190 ASN ASN L . n B 2 191 SER 191 191 191 SER SER L . n B 2 192 TYR 192 192 192 TYR TYR L . n B 2 193 THR 193 193 193 THR THR L . n B 2 194 CYS 194 194 194 CYS CYS L . n B 2 195 GLU 195 195 195 GLU GLU L . n B 2 196 ALA 196 196 196 ALA ALA L . n B 2 197 THR 197 197 197 THR THR L . n B 2 198 HIS 198 198 198 HIS HIS L . n B 2 199 LYS 199 199 199 LYS LYS L . n B 2 200 THR 200 200 200 THR THR L . n B 2 201 SER 201 201 201 SER SER L . n B 2 202 THR 202 202 202 THR THR L . n B 2 203 SER 203 203 203 SER SER L . n B 2 204 PRO 204 204 204 PRO PRO L . n B 2 205 ILE 205 205 205 ILE ILE L . n B 2 206 VAL 206 206 206 VAL VAL L . n B 2 207 LYS 207 207 207 LYS LYS L . n B 2 208 SER 208 208 208 SER SER L . n B 2 209 PHE 209 209 209 PHE PHE L . n B 2 210 ASN 210 210 210 ASN ASN L . n B 2 211 ARG 211 211 211 ARG ARG L . n B 2 212 ASN 212 212 212 ASN ASN L . n B 2 213 GLU 213 213 213 GLU GLU L . n B 2 214 CYS 214 214 214 CYS CYS L . n C 3 1 GLN 1 1 1 GLN GLN H . n C 3 2 ILE 2 2 2 ILE ILE H . n C 3 3 GLN 3 3 3 GLN GLN H . n C 3 4 LEU 4 4 4 LEU LEU H . n C 3 5 VAL 5 5 5 VAL VAL H . n C 3 6 GLN 6 6 6 GLN GLN H . n C 3 7 SER 7 7 7 SER SER H . n C 3 8 GLY 8 8 8 GLY GLY H . n C 3 9 PRO 9 9 9 PRO PRO H . n C 3 10 GLU 10 10 10 GLU GLU H . n C 3 11 LEU 11 11 11 LEU LEU H . n C 3 12 LYS 12 12 12 LYS LYS H . n C 3 13 LYS 13 13 13 LYS LYS H . n C 3 14 PRO 14 14 14 PRO PRO H . n C 3 15 GLY 15 15 15 GLY GLY H . n C 3 16 GLU 16 16 16 GLU GLU H . n C 3 17 THR 17 17 17 THR THR H . n C 3 18 VAL 18 18 18 VAL VAL H . n C 3 19 LYS 19 19 19 LYS LYS H . n C 3 20 ILE 20 20 20 ILE ILE H . n C 3 21 SER 21 21 21 SER SER H . n C 3 22 CYS 22 22 22 CYS CYS H . n C 3 23 LYS 23 23 23 LYS LYS H . n C 3 24 ALA 24 24 24 ALA ALA H . n C 3 25 SER 25 25 25 SER SER H . n C 3 26 GLY 26 26 26 GLY GLY H . n C 3 27 TYR 27 27 27 TYR TYR H . n C 3 28 THR 28 28 28 THR THR H . n C 3 29 PHE 29 29 29 PHE PHE H . n C 3 30 THR 30 30 30 THR THR H . n C 3 31 ASN 31 31 31 ASN ASN H . n C 3 32 TYR 32 32 32 TYR TYR H . n C 3 33 GLY 33 33 33 GLY GLY H . n C 3 34 MET 34 34 34 MET MET H . n C 3 35 ASN 35 35 35 ASN ASN H . n C 3 36 TRP 36 36 36 TRP TRP H . n C 3 37 VAL 37 37 37 VAL VAL H . n C 3 38 LYS 38 38 38 LYS LYS H . n C 3 39 GLN 39 39 39 GLN GLN H . n C 3 40 ALA 40 40 40 ALA ALA H . n C 3 41 PRO 41 41 41 PRO PRO H . n C 3 42 GLY 42 42 42 GLY GLY H . n C 3 43 LYS 43 43 43 LYS LYS H . n C 3 44 GLY 44 44 44 GLY GLY H . n C 3 45 LEU 45 45 45 LEU LEU H . n C 3 46 GLU 46 46 46 GLU GLU H . n C 3 47 TRP 47 47 47 TRP TRP H . n C 3 48 MET 48 48 48 MET MET H . n C 3 49 GLY 49 49 49 GLY GLY H . n C 3 50 TRP 50 50 50 TRP TRP H . n C 3 51 ILE 51 51 51 ILE ILE H . n C 3 52 ASN 52 52 52 ASN ASN H . n C 3 53 THR 53 52 52 THR THR H A n C 3 54 ASN 54 53 53 ASN ASN H . n C 3 55 THR 55 54 54 THR THR H . n C 3 56 GLY 56 55 55 GLY GLY H . n C 3 57 GLU 57 56 56 GLU GLU H . n C 3 58 PRO 58 57 57 PRO PRO H . n C 3 59 THR 59 58 58 THR THR H . n C 3 60 TYR 60 59 59 TYR TYR H . n C 3 61 GLY 61 60 60 GLY GLY H . n C 3 62 GLU 62 61 61 GLU GLU H . n C 3 63 GLU 63 62 62 GLU GLU H . n C 3 64 PHE 64 63 63 PHE PHE H . n C 3 65 LYS 65 64 64 LYS LYS H . n C 3 66 GLY 66 65 65 GLY GLY H . n C 3 67 ARG 67 66 66 ARG ARG H . n C 3 68 PHE 68 67 67 PHE PHE H . n C 3 69 ALA 69 68 68 ALA ALA H . n C 3 70 PHE 70 69 69 PHE PHE H . n C 3 71 SER 71 70 70 SER SER H . n C 3 72 LEU 72 71 71 LEU LEU H . n C 3 73 GLU 73 72 72 GLU GLU H . n C 3 74 THR 74 73 73 THR THR H . n C 3 75 SER 75 74 74 SER SER H . n C 3 76 ALA 76 75 75 ALA ALA H . n C 3 77 SER 77 76 76 SER SER H . n C 3 78 THR 78 77 77 THR THR H . n C 3 79 ALA 79 78 78 ALA ALA H . n C 3 80 ASN 80 79 79 ASN ASN H . n C 3 81 LEU 81 80 80 LEU LEU H . n C 3 82 GLN 82 81 81 GLN GLN H . n C 3 83 ILE 83 82 82 ILE ILE H . n C 3 84 ASN 84 82 82 ASN ASN H A n C 3 85 ASN 85 82 82 ASN ASN H B n C 3 86 LEU 86 82 82 LEU LEU H C n C 3 87 LYS 87 83 83 LYS LYS H . n C 3 88 ASN 88 84 84 ASN ASN H . n C 3 89 GLU 89 85 85 GLU GLU H . n C 3 90 ASP 90 86 86 ASP ASP H . n C 3 91 LYS 91 87 87 LYS LYS H . n C 3 92 ALA 92 88 88 ALA ALA H . n C 3 93 THR 93 89 89 THR THR H . n C 3 94 PHE 94 90 90 PHE PHE H . n C 3 95 PHE 95 91 91 PHE PHE H . n C 3 96 CYS 96 92 92 CYS CYS H . n C 3 97 ALA 97 93 93 ALA ALA H . n C 3 98 ARG 98 94 94 ARG ARG H . n C 3 99 GLY 99 95 95 GLY GLY H . n C 3 100 GLU 100 96 96 GLU GLU H . n C 3 101 ASP 101 97 97 ASP ASP H . n C 3 102 ASN 102 98 98 ASN ASN H . n C 3 103 PHE 103 99 99 PHE PHE H . n C 3 104 GLY 104 100 100 GLY GLY H . n C 3 105 SER 105 100 100 SER SER H A n C 3 106 LEU 106 100 100 LEU LEU H B n C 3 107 SER 107 100 100 SER SER H C n C 3 108 ASP 108 101 101 ASP ASP H . n C 3 109 TYR 109 102 102 TYR TYR H . n C 3 110 TRP 110 103 103 TRP TRP H . n C 3 111 GLY 111 104 104 GLY GLY H . n C 3 112 GLN 112 105 105 GLN GLN H . n C 3 113 GLY 113 106 106 GLY GLY H . n C 3 114 THR 114 107 107 THR THR H . n C 3 115 THR 115 108 108 THR THR H . n C 3 116 LEU 116 109 109 LEU LEU H . n C 3 117 THR 117 110 110 THR THR H . n C 3 118 VAL 118 111 111 VAL VAL H . n C 3 119 SER 119 112 112 SER SER H . n C 3 120 SER 120 113 113 SER SER H . n C 3 121 ALA 121 114 114 ALA ALA H . n C 3 122 LYS 122 115 115 LYS LYS H . n C 3 123 THR 123 116 116 THR THR H . n C 3 124 THR 124 117 117 THR THR H . n C 3 125 ALA 125 118 118 ALA ALA H . n C 3 126 PRO 126 119 119 PRO PRO H . n C 3 127 SER 127 120 120 SER SER H . n C 3 128 VAL 128 121 121 VAL VAL H . n C 3 129 TYR 129 122 122 TYR TYR H . n C 3 130 PRO 130 123 123 PRO PRO H . n C 3 131 LEU 131 124 124 LEU LEU H . n C 3 132 ALA 132 125 125 ALA ALA H . n C 3 133 PRO 133 126 126 PRO PRO H . n C 3 134 VAL 134 127 127 VAL VAL H . n C 3 135 CYS 135 128 128 CYS CYS H . n C 3 136 GLY 136 129 129 GLY GLY H . n C 3 137 ASP 137 130 130 ASP ASP H . n C 3 138 THR 138 133 133 THR THR H . n C 3 139 THR 139 134 134 THR THR H . n C 3 140 GLY 140 135 135 GLY GLY H . n C 3 141 SER 141 136 136 SER SER H . n C 3 142 SER 142 137 137 SER SER H . n C 3 143 VAL 143 138 138 VAL VAL H . n C 3 144 THR 144 139 139 THR THR H . n C 3 145 LEU 145 140 140 LEU LEU H . n C 3 146 GLY 146 141 141 GLY GLY H . n C 3 147 CYS 147 142 142 CYS CYS H . n C 3 148 LEU 148 143 143 LEU LEU H . n C 3 149 VAL 149 144 144 VAL VAL H . n C 3 150 LYS 150 145 145 LYS LYS H . n C 3 151 GLY 151 146 146 GLY GLY H . n C 3 152 TYR 152 147 147 TYR TYR H . n C 3 153 PHE 153 148 148 PHE PHE H . n C 3 154 PRO 154 149 149 PRO PRO H . n C 3 155 GLU 155 150 150 GLU GLU H . n C 3 156 PRO 156 151 151 PRO PRO H . n C 3 157 VAL 157 152 152 VAL VAL H . n C 3 158 THR 158 153 153 THR THR H . n C 3 159 LEU 159 154 154 LEU LEU H . n C 3 160 THR 160 156 156 THR THR H . n C 3 161 TRP 161 157 157 TRP TRP H . n C 3 162 ASN 162 162 162 ASN ASN H . n C 3 163 SER 163 163 163 SER SER H . n C 3 164 GLY 164 164 164 GLY GLY H . n C 3 165 SER 165 165 165 SER SER H . n C 3 166 LEU 166 166 166 LEU LEU H . n C 3 167 SER 167 167 167 SER SER H . n C 3 168 SER 168 168 168 SER SER H . n C 3 169 GLY 169 169 169 GLY GLY H . n C 3 170 VAL 170 171 171 VAL VAL H . n C 3 171 HIS 171 172 172 HIS HIS H . n C 3 172 THR 172 173 173 THR THR H . n C 3 173 PHE 173 174 174 PHE PHE H . n C 3 174 PRO 174 175 175 PRO PRO H . n C 3 175 ALA 175 176 176 ALA ALA H . n C 3 176 VAL 176 177 177 VAL VAL H . n C 3 177 LEU 177 178 178 LEU LEU H . n C 3 178 GLN 178 179 179 GLN GLN H . n C 3 179 SER 179 180 180 SER SER H . n C 3 180 ASP 180 183 183 ASP ASP H . n C 3 181 LEU 181 184 184 LEU LEU H . n C 3 182 TYR 182 185 185 TYR TYR H . n C 3 183 THR 183 186 186 THR THR H . n C 3 184 LEU 184 187 187 LEU LEU H . n C 3 185 SER 185 188 188 SER SER H . n C 3 186 SER 186 189 189 SER SER H . n C 3 187 SER 187 190 190 SER SER H . n C 3 188 VAL 188 191 191 VAL VAL H . n C 3 189 THR 189 192 192 THR THR H . n C 3 190 VAL 190 193 193 VAL VAL H . n C 3 191 THR 191 194 194 THR THR H . n C 3 192 SER 192 195 195 SER SER H . n C 3 193 SER 193 196 196 SER SER H . n C 3 194 THR 194 198 198 THR THR H . n C 3 195 TRP 195 199 199 TRP TRP H . n C 3 196 PRO 196 200 200 PRO PRO H . n C 3 197 SER 197 202 202 SER SER H . n C 3 198 GLN 198 203 203 GLN GLN H . n C 3 199 SER 199 204 204 SER SER H . n C 3 200 ILE 200 205 205 ILE ILE H . n C 3 201 THR 201 206 206 THR THR H . n C 3 202 CYS 202 208 208 CYS CYS H . n C 3 203 ASN 203 209 209 ASN ASN H . n C 3 204 VAL 204 210 210 VAL VAL H . n C 3 205 ALA 205 211 211 ALA ALA H . n C 3 206 HIS 206 212 212 HIS HIS H . n C 3 207 PRO 207 213 213 PRO PRO H . n C 3 208 ALA 208 214 214 ALA ALA H . n C 3 209 SER 209 215 215 SER SER H . n C 3 210 SER 210 216 216 SER SER H . n C 3 211 THR 211 217 217 THR THR H . n C 3 212 LYS 212 218 218 LYS LYS H . n C 3 213 VAL 213 219 219 VAL VAL H . n C 3 214 ASP 214 220 220 ASP ASP H . n C 3 215 LYS 215 221 221 LYS LYS H . n C 3 216 LYS 216 222 222 LYS LYS H . n C 3 217 ILE 217 223 223 ILE ILE H . n C 3 218 GLU 218 224 224 GLU GLU H . n C 3 219 PRO 219 225 225 PRO PRO H . n C 3 220 ARG 220 226 226 ARG ARG H . n C 3 221 GLY 221 227 227 GLY GLY H . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code D 4 NAG 1 469 200 NAG NAG N A E 4 NAG 2 470 200 NAG NAG N B F 5 BMA 3 471 200 BMA MAN N C G 6 MAN 4 472 200 MAN MAN N D H 6 MAN 5 473 200 MAN MAN N E I 6 MAN 6 474 200 MAN MAN N F J 4 NAG 1 475 86 NAG NAG N A K 4 NAG 1 476 146 NAG NAG N A L 4 NAG 2 477 146 NAG NAG N B M 7 CA 1 0 0 CA CA N . N 8 HOH 1 4 4 HOH HOH N . N 8 HOH 2 7 7 HOH HOH N . N 8 HOH 3 8 8 HOH HOH N . N 8 HOH 4 9 9 HOH HOH N . N 8 HOH 5 11 11 HOH HOH N . N 8 HOH 6 12 12 HOH HOH N . N 8 HOH 7 13 13 HOH HOH N . N 8 HOH 8 14 14 HOH HOH N . N 8 HOH 9 15 15 HOH HOH N . N 8 HOH 10 16 16 HOH HOH N . N 8 HOH 11 17 17 HOH HOH N . N 8 HOH 12 18 18 HOH HOH N . N 8 HOH 13 19 19 HOH HOH N . N 8 HOH 14 20 20 HOH HOH N . N 8 HOH 15 21 21 HOH HOH N . N 8 HOH 16 22 22 HOH HOH N . N 8 HOH 17 23 23 HOH HOH N . N 8 HOH 18 24 24 HOH HOH N . N 8 HOH 19 25 25 HOH HOH N . N 8 HOH 20 26 26 HOH HOH N . N 8 HOH 21 27 27 HOH HOH N . N 8 HOH 22 28 28 HOH HOH N . N 8 HOH 23 29 29 HOH HOH N . N 8 HOH 24 30 30 HOH HOH N . N 8 HOH 25 31 31 HOH HOH N . N 8 HOH 26 32 32 HOH HOH N . N 8 HOH 27 33 33 HOH HOH N . N 8 HOH 28 34 34 HOH HOH N . N 8 HOH 29 35 35 HOH HOH N . N 8 HOH 30 36 36 HOH HOH N . N 8 HOH 31 37 37 HOH HOH N . N 8 HOH 32 38 38 HOH HOH N . N 8 HOH 33 39 39 HOH HOH N . N 8 HOH 34 40 40 HOH HOH N . N 8 HOH 35 41 41 HOH HOH N . N 8 HOH 36 42 42 HOH HOH N . N 8 HOH 37 43 43 HOH HOH N . N 8 HOH 38 44 44 HOH HOH N . N 8 HOH 39 45 45 HOH HOH N . N 8 HOH 40 46 46 HOH HOH N . N 8 HOH 41 47 47 HOH HOH N . N 8 HOH 42 48 48 HOH HOH N . N 8 HOH 43 49 49 HOH HOH N . N 8 HOH 44 50 50 HOH HOH N . N 8 HOH 45 51 51 HOH HOH N . N 8 HOH 46 52 52 HOH HOH N . N 8 HOH 47 53 53 HOH HOH N . N 8 HOH 48 54 54 HOH HOH N . N 8 HOH 49 55 55 HOH HOH N . N 8 HOH 50 56 56 HOH HOH N . N 8 HOH 51 57 57 HOH HOH N . N 8 HOH 52 58 58 HOH HOH N . N 8 HOH 53 59 59 HOH HOH N . N 8 HOH 54 60 60 HOH HOH N . N 8 HOH 55 61 61 HOH HOH N . N 8 HOH 56 62 62 HOH HOH N . N 8 HOH 57 63 63 HOH HOH N . N 8 HOH 58 64 64 HOH HOH N . N 8 HOH 59 65 65 HOH HOH N . N 8 HOH 60 66 66 HOH HOH N . N 8 HOH 61 67 67 HOH HOH N . N 8 HOH 62 68 68 HOH HOH N . N 8 HOH 63 69 69 HOH HOH N . N 8 HOH 64 70 70 HOH HOH N . N 8 HOH 65 71 71 HOH HOH N . N 8 HOH 66 72 72 HOH HOH N . O 8 HOH 1 215 1 HOH HOH L . O 8 HOH 2 216 6 HOH HOH L . P 8 HOH 1 228 2 HOH HOH H . P 8 HOH 2 229 3 HOH HOH H . P 8 HOH 3 230 5 HOH HOH H . P 8 HOH 4 231 10 HOH HOH H . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 6 N ASN 86 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 66 N ASN 146 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 121 N ASN 200 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA,PQS dodecameric 12 2 software_defined_assembly PISA eicosameric 20 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1,2,3,4 A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P 2 1,2,3,4 A,C,D,E,F,G,H,I,J,K,L,M,N,P 2 5,6,7,8 A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 47710 ? 1 MORE -72 ? 1 'SSA (A^2)' 116950 ? 2 'ABSA (A^2)' 44320 ? 2 MORE -61 ? 2 'SSA (A^2)' 120340 ? # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 2_655 -x+1,-y,z -1.0000000000 0.0000000000 0.0000000000 167.0000000000 0.0000000000 -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 3 'crystal symmetry operation' 3_545 -y+1/2,x-1/2,z 0.0000000000 -1.0000000000 0.0000000000 83.5000000000 1.0000000000 0.0000000000 0.0000000000 -83.5000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 4 'crystal symmetry operation' 4_555 y+1/2,-x+1/2,z 0.0000000000 1.0000000000 0.0000000000 83.5000000000 -1.0000000000 0.0000000000 0.0000000000 83.5000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 5 'crystal symmetry operation' 5_547 -x+1/2,y-1/2,-z+2 -1.0000000000 0.0000000000 0.0000000000 83.5000000000 0.0000000000 1.0000000000 0.0000000000 -83.5000000000 0.0000000000 0.0000000000 -1.0000000000 248.0000000000 6 'crystal symmetry operation' 6_557 x+1/2,-y+1/2,-z+2 1.0000000000 0.0000000000 0.0000000000 83.5000000000 0.0000000000 -1.0000000000 0.0000000000 83.5000000000 0.0000000000 0.0000000000 -1.0000000000 248.0000000000 7 'crystal symmetry operation' 7_557 y,x,-z+2 0.0000000000 1.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 248.0000000000 8 'crystal symmetry operation' 8_657 -y+1,-x,-z+2 0.0000000000 -1.0000000000 0.0000000000 167.0000000000 -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 248.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 O ? A ASN 267 ? N ASN 347 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 OD2 ? A ASP 245 ? N ASP 324 ? 1_555 103.6 ? 2 O ? A ASN 267 ? N ASN 347 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A GLY 218 ? N GLY 297 ? 1_555 172.2 ? 3 OD2 ? A ASP 245 ? N ASP 324 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A GLY 218 ? N GLY 297 ? 1_555 69.3 ? 4 O ? A ASN 267 ? N ASN 347 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASP 214 ? N ASP 293 ? 1_555 99.8 ? 5 OD2 ? A ASP 245 ? N ASP 324 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASP 214 ? N ASP 293 ? 1_555 79.8 ? 6 O ? A GLY 218 ? N GLY 297 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASP 214 ? N ASP 293 ? 1_555 82.4 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 1994-01-31 2 'Structure model' 1 1 2008-03-24 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Derived calculations' 3 3 'Structure model' 'Source and taxonomy' 4 3 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal X-PLOR 'model building' . ? 1 X-PLOR refinement . ? 2 X-PLOR phasing . ? 3 # loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 NE2 N HIS 98 ? ? CD2 N HIS 98 ? ? 1.307 1.373 -0.066 0.011 N 2 1 NE2 N HIS 144 ? ? CD2 N HIS 144 ? ? 1.297 1.373 -0.076 0.011 N 3 1 NE2 N HIS 150 ? ? CD2 N HIS 150 ? ? 1.305 1.373 -0.068 0.011 N 4 1 NE2 N HIS 184 ? ? CD2 N HIS 184 ? ? 1.301 1.373 -0.072 0.011 N 5 1 NE2 N HIS 274 ? ? CD2 N HIS 274 ? ? 1.299 1.373 -0.074 0.011 N 6 1 NE2 N HIS 312 ? ? CD2 N HIS 312 ? ? 1.296 1.373 -0.077 0.011 N 7 1 NE2 L HIS 91 ? ? CD2 L HIS 91 ? ? 1.298 1.373 -0.075 0.011 N 8 1 NE2 L HIS 189 ? ? CD2 L HIS 189 ? ? 1.305 1.373 -0.068 0.011 N 9 1 NE2 L HIS 198 ? ? CD2 L HIS 198 ? ? 1.291 1.373 -0.082 0.011 N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CE2 N TRP 97 ? ? CD2 N TRP 97 ? ? CG N TRP 97 ? ? 102.33 107.30 -4.97 0.80 N 2 1 CA N TYR 121 ? ? CB N TYR 121 ? ? CG N TYR 121 ? ? 125.71 113.40 12.31 1.90 N 3 1 N N ASP 127 ? ? CA N ASP 127 ? ? CB N ASP 127 ? ? 99.21 110.60 -11.39 1.80 N 4 1 CB N TYR 132 ? ? CG N TYR 132 ? ? CD2 N TYR 132 ? ? 117.01 121.00 -3.99 0.60 N 5 1 NE N ARG 156 ? ? CZ N ARG 156 ? ? NH1 N ARG 156 ? ? 123.53 120.30 3.23 0.50 N 6 1 CD1 N TRP 161 ? ? CG N TRP 161 ? ? CD2 N TRP 161 ? ? 112.04 106.30 5.74 0.80 N 7 1 CE2 N TRP 161 ? ? CD2 N TRP 161 ? ? CG N TRP 161 ? ? 101.60 107.30 -5.70 0.80 N 8 1 CD1 N TRP 178 ? ? CG N TRP 178 ? ? CD2 N TRP 178 ? ? 112.55 106.30 6.25 0.80 N 9 1 CE2 N TRP 178 ? ? CD2 N TRP 178 ? ? CG N TRP 178 ? ? 101.59 107.30 -5.71 0.80 N 10 1 CB N HIS 184 ? ? CG N HIS 184 ? ? CD2 N HIS 184 ? ? 120.01 129.70 -9.69 1.60 N 11 1 CA N MET 190 ? ? CB N MET 190 ? ? CG N MET 190 ? ? 101.89 113.30 -11.41 1.70 N 12 1 NE N ARG 210 ? ? CZ N ARG 210 ? ? NH2 N ARG 210 ? ? 117.16 120.30 -3.14 0.50 N 13 1 CD1 N TRP 218 ? ? CG N TRP 218 ? ? CD2 N TRP 218 ? ? 114.56 106.30 8.26 0.80 N 14 1 CG N TRP 218 ? ? CD1 N TRP 218 ? ? NE1 N TRP 218 ? ? 102.90 110.10 -7.20 1.00 N 15 1 CE2 N TRP 218 ? ? CD2 N TRP 218 ? ? CG N TRP 218 ? ? 100.72 107.30 -6.58 0.80 N 16 1 CG N TRP 218 ? ? CD2 N TRP 218 ? ? CE3 N TRP 218 ? ? 140.04 133.90 6.14 0.90 N 17 1 CA N CYS 232 ? ? CB N CYS 232 ? ? SG N CYS 232 ? ? 122.49 114.20 8.29 1.10 N 18 1 CG1 N VAL 239 ? ? CB N VAL 239 ? ? CG2 N VAL 239 ? ? 101.18 110.90 -9.72 1.60 N 19 1 CB N ASP 243 ? ? CG N ASP 243 ? ? OD1 N ASP 243 ? ? 125.27 118.30 6.97 0.90 N 20 1 CD1 N TRP 265 ? ? CG N TRP 265 ? ? CD2 N TRP 265 ? ? 112.02 106.30 5.72 0.80 N 21 1 CE2 N TRP 265 ? ? CD2 N TRP 265 ? ? CG N TRP 265 ? ? 101.49 107.30 -5.81 0.80 N 22 1 NE N ARG 284 ? ? CZ N ARG 284 ? ? NH1 N ARG 284 ? ? 126.97 120.30 6.67 0.50 N 23 1 NE N ARG 292 ? ? CZ N ARG 292 ? ? NH1 N ARG 292 ? ? 123.42 120.30 3.12 0.50 N 24 1 CA N ASP 293 ? ? C N ASP 293 ? ? N N ASN 294 ? ? 100.48 117.20 -16.72 2.20 Y 25 1 CD1 N TRP 295 ? ? CG N TRP 295 ? ? CD2 N TRP 295 ? ? 111.83 106.30 5.53 0.80 N 26 1 CE2 N TRP 295 ? ? CD2 N TRP 295 ? ? CG N TRP 295 ? ? 102.33 107.30 -4.97 0.80 N 27 1 CA N GLY 297 ? ? C N GLY 297 ? ? N N SER 298 ? ? 98.74 117.20 -18.46 2.20 Y 28 1 O N GLY 297 ? ? C N GLY 297 ? ? N N SER 298 ? ? 133.90 122.70 11.20 1.60 Y 29 1 CA N ASN 347 ? ? C N ASN 347 ? ? N N GLY 348 ? ? 102.62 116.20 -13.58 2.00 Y 30 1 CD1 N TRP 361 ? ? CG N TRP 361 ? ? CD2 N TRP 361 ? ? 113.21 106.30 6.91 0.80 N 31 1 CE2 N TRP 361 ? ? CD2 N TRP 361 ? ? CG N TRP 361 ? ? 101.72 107.30 -5.58 0.80 N 32 1 CD1 N TRP 403 ? ? CG N TRP 403 ? ? CD2 N TRP 403 ? ? 111.79 106.30 5.49 0.80 N 33 1 CE2 N TRP 403 ? ? CD2 N TRP 403 ? ? CG N TRP 403 ? ? 101.54 107.30 -5.76 0.80 N 34 1 CD1 N TRP 412 B ? CG N TRP 412 B ? CD2 N TRP 412 B ? 111.69 106.30 5.39 0.80 N 35 1 CB N TRP 412 B ? CG N TRP 412 B ? CD1 N TRP 412 B ? 119.19 127.00 -7.81 1.30 N 36 1 CE2 N TRP 412 B ? CD2 N TRP 412 B ? CG N TRP 412 B ? 101.52 107.30 -5.78 0.80 N 37 1 CA N CYS 421 ? ? CB N CYS 421 ? ? SG N CYS 421 ? ? 121.24 114.20 7.04 1.10 N 38 1 NE N ARG 430 ? ? CZ N ARG 430 ? ? NH1 N ARG 430 ? ? 123.82 120.30 3.52 0.50 N 39 1 CD1 N TRP 437 ? ? CG N TRP 437 ? ? CD2 N TRP 437 ? ? 112.57 106.30 6.27 0.80 N 40 1 CE2 N TRP 437 ? ? CD2 N TRP 437 ? ? CG N TRP 437 ? ? 101.69 107.30 -5.61 0.80 N 41 1 CD1 N TRP 438 ? ? CG N TRP 438 ? ? CD2 N TRP 438 ? ? 111.12 106.30 4.82 0.80 N 42 1 CB N TRP 438 ? ? CG N TRP 438 ? ? CD1 N TRP 438 ? ? 118.27 127.00 -8.73 1.30 N 43 1 CG N TRP 438 ? ? CD2 N TRP 438 ? ? CE3 N TRP 438 ? ? 140.66 133.90 6.76 0.90 N 44 1 CD1 N TRP 456 ? ? CG N TRP 456 ? ? CD2 N TRP 456 ? ? 111.98 106.30 5.68 0.80 N 45 1 CE2 N TRP 456 ? ? CD2 N TRP 456 ? ? CG N TRP 456 ? ? 101.57 107.30 -5.73 0.80 N 46 1 CA L VAL 3 ? ? CB L VAL 3 ? ? CG2 L VAL 3 ? ? 101.48 110.90 -9.42 1.50 N 47 1 CG L MET 11 ? ? SD L MET 11 ? ? CE L MET 11 ? ? 90.41 100.20 -9.79 1.60 N 48 1 CA L VAL 33 ? ? CB L VAL 33 ? ? CG2 L VAL 33 ? ? 101.12 110.90 -9.78 1.50 N 49 1 CE2 L TRP 35 ? ? CD2 L TRP 35 ? ? CG L TRP 35 ? ? 102.43 107.30 -4.87 0.80 N 50 1 CB L TYR 36 ? ? CG L TYR 36 ? ? CD2 L TYR 36 ? ? 117.37 121.00 -3.63 0.60 N 51 1 CD1 L TRP 50 ? ? CG L TRP 50 ? ? CD2 L TRP 50 ? ? 113.75 106.30 7.45 0.80 N 52 1 CE2 L TRP 50 ? ? CD2 L TRP 50 ? ? CG L TRP 50 ? ? 101.03 107.30 -6.27 0.80 N 53 1 NE L ARG 54 ? ? CZ L ARG 54 ? ? NH1 L ARG 54 ? ? 127.06 120.30 6.76 0.50 N 54 1 NE L ARG 54 ? ? CZ L ARG 54 ? ? NH2 L ARG 54 ? ? 116.78 120.30 -3.52 0.50 N 55 1 NE L ARG 61 ? ? CZ L ARG 61 ? ? NH2 L ARG 61 ? ? 116.79 120.30 -3.51 0.50 N 56 1 CG1 L VAL 78 ? ? CB L VAL 78 ? ? CG2 L VAL 78 ? ? 100.70 110.90 -10.20 1.60 N 57 1 CA L GLN 79 ? ? CB L GLN 79 ? ? CG L GLN 79 ? ? 130.32 113.40 16.92 2.20 N 58 1 CB L TYR 87 ? ? CG L TYR 87 ? ? CD1 L TYR 87 ? ? 116.80 121.00 -4.20 0.60 N 59 1 CD1 L TRP 96 ? ? CG L TRP 96 ? ? CD2 L TRP 96 ? ? 113.60 106.30 7.30 0.80 N 60 1 CE2 L TRP 96 ? ? CD2 L TRP 96 ? ? CG L TRP 96 ? ? 100.68 107.30 -6.62 0.80 N 61 1 CA L LYS 107 ? ? C L LYS 107 ? ? N L ARG 108 ? ? 103.03 117.20 -14.17 2.20 Y 62 1 CB L TYR 140 ? ? CG L TYR 140 ? ? CD1 L TYR 140 ? ? 115.48 121.00 -5.52 0.60 N 63 1 CD1 L TRP 148 ? ? CG L TRP 148 ? ? CD2 L TRP 148 ? ? 114.40 106.30 8.10 0.80 N 64 1 CG L TRP 148 ? ? CD1 L TRP 148 ? ? NE1 L TRP 148 ? ? 104.06 110.10 -6.04 1.00 N 65 1 CE2 L TRP 148 ? ? CD2 L TRP 148 ? ? CG L TRP 148 ? ? 101.03 107.30 -6.27 0.80 N 66 1 NE L ARG 155 ? ? CZ L ARG 155 ? ? NH2 L ARG 155 ? ? 116.56 120.30 -3.74 0.50 N 67 1 CD1 L TRP 163 ? ? CG L TRP 163 ? ? CD2 L TRP 163 ? ? 112.21 106.30 5.91 0.80 N 68 1 CE2 L TRP 163 ? ? CD2 L TRP 163 ? ? CG L TRP 163 ? ? 101.68 107.30 -5.62 0.80 N 69 1 CA L SER 201 ? ? C L SER 201 ? ? N L THR 202 ? ? 102.93 117.20 -14.27 2.20 Y 70 1 CB H TYR 27 ? ? CG H TYR 27 ? ? CD1 H TYR 27 ? ? 116.98 121.00 -4.02 0.60 N 71 1 CD1 H TRP 36 ? ? CG H TRP 36 ? ? CD2 H TRP 36 ? ? 113.79 106.30 7.49 0.80 N 72 1 CG H TRP 36 ? ? CD1 H TRP 36 ? ? NE1 H TRP 36 ? ? 104.00 110.10 -6.10 1.00 N 73 1 CE2 H TRP 36 ? ? CD2 H TRP 36 ? ? CG H TRP 36 ? ? 101.29 107.30 -6.01 0.80 N 74 1 CD1 H TRP 47 ? ? CG H TRP 47 ? ? CD2 H TRP 47 ? ? 111.14 106.30 4.84 0.80 N 75 1 CE2 H TRP 47 ? ? CD2 H TRP 47 ? ? CG H TRP 47 ? ? 101.99 107.30 -5.31 0.80 N 76 1 CD1 H TRP 50 ? ? CG H TRP 50 ? ? CD2 H TRP 50 ? ? 112.42 106.30 6.12 0.80 N 77 1 CE2 H TRP 50 ? ? CD2 H TRP 50 ? ? CG H TRP 50 ? ? 102.10 107.30 -5.20 0.80 N 78 1 CA H PRO 57 ? ? C H PRO 57 ? ? N H THR 58 ? ? 103.75 117.20 -13.45 2.20 Y 79 1 CB H ARG 94 ? ? CG H ARG 94 ? ? CD H ARG 94 ? ? 92.59 111.60 -19.01 2.60 N 80 1 CD1 H TRP 103 ? ? CG H TRP 103 ? ? CD2 H TRP 103 ? ? 113.79 106.30 7.49 0.80 N 81 1 CG H TRP 103 ? ? CD1 H TRP 103 ? ? NE1 H TRP 103 ? ? 103.74 110.10 -6.36 1.00 N 82 1 CE2 H TRP 103 ? ? CD2 H TRP 103 ? ? CG H TRP 103 ? ? 101.56 107.30 -5.74 0.80 N 83 1 CA H CYS 128 ? ? CB H CYS 128 ? ? SG H CYS 128 ? ? 123.79 114.20 9.59 1.10 N 84 1 CG1 H VAL 152 ? ? CB H VAL 152 ? ? CG2 H VAL 152 ? ? 99.66 110.90 -11.24 1.60 N 85 1 CD1 H TRP 157 ? ? CG H TRP 157 ? ? CD2 H TRP 157 ? ? 112.75 106.30 6.45 0.80 N 86 1 CE2 H TRP 157 ? ? CD2 H TRP 157 ? ? CG H TRP 157 ? ? 101.43 107.30 -5.87 0.80 N 87 1 CB H TYR 185 ? ? CG H TYR 185 ? ? CD2 H TYR 185 ? ? 116.58 121.00 -4.42 0.60 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 SER N 96 ? ? -164.71 -166.64 2 1 ASP N 111 ? ? -146.78 39.78 3 1 ALA N 133 ? ? 179.70 155.33 4 1 LYS N 143 ? ? -59.77 -2.14 5 1 SER N 153 ? ? -173.35 -177.69 6 1 ALA N 157 ? ? -172.55 129.39 7 1 ASN N 200 ? ? -163.36 60.43 8 1 VAL N 212 ? ? -110.08 -72.28 9 1 ILE N 222 ? ? 37.81 90.53 10 1 GLN N 226 ? ? -23.29 -52.46 11 1 LYS N 264 ? ? 179.47 172.47 12 1 ALA N 285 ? ? 45.53 27.64 13 1 CYS N 291 ? ? -122.00 -156.58 14 1 GLN N 315 ? ? -129.22 -167.67 15 1 SER N 319 ? ? -37.35 134.13 16 1 VAL N 321 ? ? -66.31 89.07 17 1 PRO N 328 ? ? -47.64 155.51 18 1 PRO N 331 ? ? -71.07 -168.61 19 1 ASN N 347 ? ? 172.76 156.23 20 1 VAL N 349 ? ? -175.02 131.31 21 1 ASP N 356 ? ? -144.77 36.13 22 1 ASN N 359 ? ? -67.17 42.27 23 1 GLN N 395 ? ? -167.24 119.98 24 1 SER N 404 ? ? -124.22 -144.80 25 1 GLU N 433 ? ? -115.81 68.41 26 1 SER N 440 ? ? -120.63 -163.70 27 1 GLU N 451 ? ? -59.19 175.30 28 1 ILE N 464 ? ? -54.38 -6.73 29 1 ASP L 17 ? ? -99.11 -150.77 30 1 SER L 26 ? ? -95.47 38.85 31 1 GLN L 27 ? ? 171.74 161.79 32 1 PRO L 40 ? ? -39.63 103.76 33 1 ALA L 51 ? ? 66.96 -50.90 34 1 ASP L 60 ? ? -42.33 -10.59 35 1 PRO L 94 ? ? -48.54 154.44 36 1 PRO L 119 ? ? -39.75 157.07 37 1 ASN L 138 ? ? 62.91 63.23 38 1 PRO L 141 ? ? -64.16 -177.10 39 1 ASN L 157 ? ? 125.55 150.00 40 1 ASP L 170 ? ? -113.51 54.49 41 1 SER L 171 ? ? 11.95 55.23 42 1 GLU L 187 ? ? -59.15 3.02 43 1 ASN L 190 ? ? -141.97 -50.27 44 1 PRO L 204 ? ? -24.70 133.18 45 1 PRO H 14 ? ? -28.11 144.37 46 1 PRO H 41 ? ? -46.45 -82.96 47 1 LYS H 43 ? ? -171.75 -61.82 48 1 GLU H 62 ? ? -48.27 -4.91 49 1 ASN H 82 B ? 59.47 74.09 50 1 LEU H 82 C ? -64.20 82.83 51 1 ALA H 88 ? ? -177.94 -176.58 52 1 PHE H 99 ? ? 69.65 -13.47 53 1 TYR H 102 ? ? 53.29 100.02 54 1 CYS H 128 ? ? 45.49 -102.44 55 1 ASP H 130 ? ? -53.90 100.42 56 1 THR H 134 ? ? 78.32 162.84 57 1 ASN H 162 ? ? 69.19 101.79 58 1 SER H 163 ? ? 22.77 44.56 59 1 SER H 180 ? ? 58.56 -78.99 60 1 PRO H 225 ? ? -40.47 -13.74 61 1 ARG H 226 ? ? -10.44 85.41 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 PHE _pdbx_validate_peptide_omega.auth_asym_id_1 L _pdbx_validate_peptide_omega.auth_seq_id_1 209 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 ASN _pdbx_validate_peptide_omega.auth_asym_id_2 L _pdbx_validate_peptide_omega.auth_seq_id_2 210 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega 145.89 # loop_ _pdbx_validate_planes.id _pdbx_validate_planes.PDB_model_num _pdbx_validate_planes.auth_comp_id _pdbx_validate_planes.auth_asym_id _pdbx_validate_planes.auth_seq_id _pdbx_validate_planes.PDB_ins_code _pdbx_validate_planes.label_alt_id _pdbx_validate_planes.rmsd _pdbx_validate_planes.type 1 1 ARG N 107 ? ? 0.079 'SIDE CHAIN' 2 1 ARG N 118 ? ? 0.073 'SIDE CHAIN' 3 1 ARG N 210 ? ? 0.082 'SIDE CHAIN' 4 1 ARG N 224 ? ? 0.079 'SIDE CHAIN' 5 1 TYR N 406 ? ? 0.065 'SIDE CHAIN' 6 1 TYR L 140 ? ? 0.099 'SIDE CHAIN' # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 4 N-ACETYL-D-GLUCOSAMINE NAG 5 BETA-D-MANNOSE BMA 6 ALPHA-D-MANNOSE MAN 7 'CALCIUM ION' CA 8 water HOH #