data_1H15 # _entry.id 1H15 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 1H15 PDBE EBI-9971 WWPDB D_1290009971 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.content_type _pdbx_database_related.details PDB 1A6A unspecified 'THE STRUCTURE OF AN INTERMEDIATE IN CLASS II MHC MATURATION: CLIP BOUND TO HLA-DR3' PDB 1AQD unspecified 'HLA-DR1 (DRA, DRB1 0101) HUMAN CLASS II HISTOCOMPATIBILITYPROTEIN (EXTRACELLULAR DOMAIN) COMPLEXED WITH ENDOGENOUSPEPTIDE' PDB 1D5M unspecified 'X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDE' PDB 1D5X unspecified 'X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH DIPEPTIDE MIMETIC' PDB 1D5Z unspecified 'X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDOMIMETIC' PDB 1D6E unspecified 'CRYSTAL STRUCTURE OF HLA-DR4 COMPLEX WITH PEPTIDOMIMETIC AND SEB' PDB 1DLH unspecified . PDB 1FV1 unspecified ;STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANTPEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES ; PDB 1HQR unspecified 'CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II' PDB 1HXY unspecified 'CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN H INCOMPLEX WITH HUMAN MHC CLASS II' PDB 1J8H unspecified ;CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELLRECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS IIMOLECULE, HLA-DR4 ; PDB 1KG0 unspecified 'STRUCTURE OF THE EPSTEIN-BARR VIRUS GP42 PROTEIN BOUND TOTHE MHC CLASS II RECEPTOR HLA-DR1' PDB 1SEB unspecified 'COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 ANDTHE BACTERIAL SUPERANTIGEN SEB' PDB 2SEB unspecified 'X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH A PEPTIDE FROM HUMAN COLLAGEN II' # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 1H15 _pdbx_database_status.deposit_site PDBE _pdbx_database_status.process_site PDBE _pdbx_database_status.SG_entry . _pdbx_database_status.recvd_initial_deposition_date 2002-07-02 _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Lang, H.' 1 'Jacobsen, H.' 2 'Ikemizu, S.' 3 'Andersson, C.' 4 'Harlos, K.' 5 'Madsen, L.' 6 'Hjorth, P.' 7 'Sondergaard, L.' 8 'Svejgaard, A.' 9 'Wucherpfennig, K.' 10 'Stuart, D.I.' 11 'Bell, J.I.' 12 'Jones, E.Y.' 13 'Fugger, L.' 14 # _citation.id primary _citation.title 'A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis' _citation.journal_abbrev Nat.Immunol. _citation.journal_volume 3 _citation.page_first 940 _citation.page_last ? _citation.year 2002 _citation.journal_id_ASTM ? _citation.country UK _citation.journal_id_ISSN 1529-2908 _citation.journal_id_CSD ? _citation.book_publisher ? _citation.pdbx_database_id_PubMed 12244309 _citation.pdbx_database_id_DOI 10.1038/NI835 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Lang, H.' 1 primary 'Jacobsen, H.' 2 primary 'Ikemizu, S.' 3 primary 'Andersson, C.' 4 primary 'Harlos, K.' 5 primary 'Madsen, L.' 6 primary 'Hjorth, P.' 7 primary 'Sondergaard, L.' 8 primary 'Svejgaard, A.' 9 primary 'Wucherpfennig, K.' 10 primary 'Stuart, D.I.' 11 primary 'Bell, J.I.' 12 primary 'Jones, E.Y.' 13 primary 'Fugger, L.' 14 # _cell.entry_id 1H15 _cell.length_a 179.244 _cell.length_b 179.244 _cell.length_c 92.884 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 12 _cell.pdbx_unique_axis ? # _symmetry.entry_id 1H15 _symmetry.space_group_name_H-M 'P 65' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 170 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN' 21155.904 2 ? ? 'ALPHA CHAIN, RESIDUES 26-207' ? 2 polymer man 'HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 1 CHAIN' 22231.574 2 ? ? 'BETA CHAIN, RESIDUES 30-219' ? 3 polymer syn 'DNA POLYMERASE' 1628.850 2 2.7.7.7 ? 'RESIDUES 628-641' ? 4 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 5 ? ? ? ? 5 water nat water 18.015 30 ? ? ? ? # loop_ _entity_name_com.entity_id _entity_name_com.name 1 'HLA-DRA, MAJOR HISTOCOMPATIBILITY COMPLEX A CHAIN' 2 'HLA-DRB1, MAJOR HISTOCOMPATIBILITY COMPLEX B CHAIN' 3 'EPSTEIN BARR VIUS (EBV) DNA POLYMERASE' # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;IKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYT PITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDV YDCRVEHWGLDEPLLKHWEFDA ; ;IKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYT PITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDV YDCRVEHWGLDEPLLKHWEFDA ; A,D ? 2 'polypeptide(L)' no no ;GDTRPRFLQQDKYECHFFNGTERVRFLHRDIYNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCR HNYGVGESFTVQRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVM LETVPRSGEVYTCQVEHPSVTSPLTVEWRA ; ;GDTRPRFLQQDKYECHFFNGTERVRFLHRDIYNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCR HNYGVGESFTVQRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVM LETVPRSGEVYTCQVEHPSVTSPLTVEWRA ; B,E ? 3 'polypeptide(L)' no no GGVYHFVKKHVHES GGVYHFVKKHVHES C,F ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ILE n 1 2 LYS n 1 3 GLU n 1 4 GLU n 1 5 HIS n 1 6 VAL n 1 7 ILE n 1 8 ILE n 1 9 GLN n 1 10 ALA n 1 11 GLU n 1 12 PHE n 1 13 TYR n 1 14 LEU n 1 15 ASN n 1 16 PRO n 1 17 ASP n 1 18 GLN n 1 19 SER n 1 20 GLY n 1 21 GLU n 1 22 PHE n 1 23 MET n 1 24 PHE n 1 25 ASP n 1 26 PHE n 1 27 ASP n 1 28 GLY n 1 29 ASP n 1 30 GLU n 1 31 ILE n 1 32 PHE n 1 33 HIS n 1 34 VAL n 1 35 ASP n 1 36 MET n 1 37 ALA n 1 38 LYS n 1 39 LYS n 1 40 GLU n 1 41 THR n 1 42 VAL n 1 43 TRP n 1 44 ARG n 1 45 LEU n 1 46 GLU n 1 47 GLU n 1 48 PHE n 1 49 GLY n 1 50 ARG n 1 51 PHE n 1 52 ALA n 1 53 SER n 1 54 PHE n 1 55 GLU n 1 56 ALA n 1 57 GLN n 1 58 GLY n 1 59 ALA n 1 60 LEU n 1 61 ALA n 1 62 ASN n 1 63 ILE n 1 64 ALA n 1 65 VAL n 1 66 ASP n 1 67 LYS n 1 68 ALA n 1 69 ASN n 1 70 LEU n 1 71 GLU n 1 72 ILE n 1 73 MET n 1 74 THR n 1 75 LYS n 1 76 ARG n 1 77 SER n 1 78 ASN n 1 79 TYR n 1 80 THR n 1 81 PRO n 1 82 ILE n 1 83 THR n 1 84 ASN n 1 85 VAL n 1 86 PRO n 1 87 PRO n 1 88 GLU n 1 89 VAL n 1 90 THR n 1 91 VAL n 1 92 LEU n 1 93 THR n 1 94 ASN n 1 95 SER n 1 96 PRO n 1 97 VAL n 1 98 GLU n 1 99 LEU n 1 100 ARG n 1 101 GLU n 1 102 PRO n 1 103 ASN n 1 104 VAL n 1 105 LEU n 1 106 ILE n 1 107 CYS n 1 108 PHE n 1 109 ILE n 1 110 ASP n 1 111 LYS n 1 112 PHE n 1 113 THR n 1 114 PRO n 1 115 PRO n 1 116 VAL n 1 117 VAL n 1 118 ASN n 1 119 VAL n 1 120 THR n 1 121 TRP n 1 122 LEU n 1 123 ARG n 1 124 ASN n 1 125 GLY n 1 126 LYS n 1 127 PRO n 1 128 VAL n 1 129 THR n 1 130 THR n 1 131 GLY n 1 132 VAL n 1 133 SER n 1 134 GLU n 1 135 THR n 1 136 VAL n 1 137 PHE n 1 138 LEU n 1 139 PRO n 1 140 ARG n 1 141 GLU n 1 142 ASP n 1 143 HIS n 1 144 LEU n 1 145 PHE n 1 146 ARG n 1 147 LYS n 1 148 PHE n 1 149 HIS n 1 150 TYR n 1 151 LEU n 1 152 PRO n 1 153 PHE n 1 154 LEU n 1 155 PRO n 1 156 SER n 1 157 THR n 1 158 GLU n 1 159 ASP n 1 160 VAL n 1 161 TYR n 1 162 ASP n 1 163 CYS n 1 164 ARG n 1 165 VAL n 1 166 GLU n 1 167 HIS n 1 168 TRP n 1 169 GLY n 1 170 LEU n 1 171 ASP n 1 172 GLU n 1 173 PRO n 1 174 LEU n 1 175 LEU n 1 176 LYS n 1 177 HIS n 1 178 TRP n 1 179 GLU n 1 180 PHE n 1 181 ASP n 1 182 ALA n 2 1 GLY n 2 2 ASP n 2 3 THR n 2 4 ARG n 2 5 PRO n 2 6 ARG n 2 7 PHE n 2 8 LEU n 2 9 GLN n 2 10 GLN n 2 11 ASP n 2 12 LYS n 2 13 TYR n 2 14 GLU n 2 15 CYS n 2 16 HIS n 2 17 PHE n 2 18 PHE n 2 19 ASN n 2 20 GLY n 2 21 THR n 2 22 GLU n 2 23 ARG n 2 24 VAL n 2 25 ARG n 2 26 PHE n 2 27 LEU n 2 28 HIS n 2 29 ARG n 2 30 ASP n 2 31 ILE n 2 32 TYR n 2 33 ASN n 2 34 GLN n 2 35 GLU n 2 36 GLU n 2 37 ASP n 2 38 LEU n 2 39 ARG n 2 40 PHE n 2 41 ASP n 2 42 SER n 2 43 ASP n 2 44 VAL n 2 45 GLY n 2 46 GLU n 2 47 TYR n 2 48 ARG n 2 49 ALA n 2 50 VAL n 2 51 THR n 2 52 GLU n 2 53 LEU n 2 54 GLY n 2 55 ARG n 2 56 PRO n 2 57 ASP n 2 58 ALA n 2 59 GLU n 2 60 TYR n 2 61 TRP n 2 62 ASN n 2 63 SER n 2 64 GLN n 2 65 LYS n 2 66 ASP n 2 67 PHE n 2 68 LEU n 2 69 GLU n 2 70 ASP n 2 71 ARG n 2 72 ARG n 2 73 ALA n 2 74 ALA n 2 75 VAL n 2 76 ASP n 2 77 THR n 2 78 TYR n 2 79 CYS n 2 80 ARG n 2 81 HIS n 2 82 ASN n 2 83 TYR n 2 84 GLY n 2 85 VAL n 2 86 GLY n 2 87 GLU n 2 88 SER n 2 89 PHE n 2 90 THR n 2 91 VAL n 2 92 GLN n 2 93 ARG n 2 94 ARG n 2 95 VAL n 2 96 GLU n 2 97 PRO n 2 98 LYS n 2 99 VAL n 2 100 THR n 2 101 VAL n 2 102 TYR n 2 103 PRO n 2 104 ALA n 2 105 ARG n 2 106 THR n 2 107 GLN n 2 108 THR n 2 109 LEU n 2 110 GLN n 2 111 HIS n 2 112 HIS n 2 113 ASN n 2 114 LEU n 2 115 LEU n 2 116 VAL n 2 117 CYS n 2 118 SER n 2 119 VAL n 2 120 ASN n 2 121 GLY n 2 122 PHE n 2 123 TYR n 2 124 PRO n 2 125 GLY n 2 126 SER n 2 127 ILE n 2 128 GLU n 2 129 VAL n 2 130 ARG n 2 131 TRP n 2 132 PHE n 2 133 ARG n 2 134 ASN n 2 135 SER n 2 136 GLN n 2 137 GLU n 2 138 GLU n 2 139 LYS n 2 140 ALA n 2 141 GLY n 2 142 VAL n 2 143 VAL n 2 144 SER n 2 145 THR n 2 146 GLY n 2 147 LEU n 2 148 ILE n 2 149 GLN n 2 150 ASN n 2 151 GLY n 2 152 ASP n 2 153 TRP n 2 154 THR n 2 155 PHE n 2 156 GLN n 2 157 THR n 2 158 LEU n 2 159 VAL n 2 160 MET n 2 161 LEU n 2 162 GLU n 2 163 THR n 2 164 VAL n 2 165 PRO n 2 166 ARG n 2 167 SER n 2 168 GLY n 2 169 GLU n 2 170 VAL n 2 171 TYR n 2 172 THR n 2 173 CYS n 2 174 GLN n 2 175 VAL n 2 176 GLU n 2 177 HIS n 2 178 PRO n 2 179 SER n 2 180 VAL n 2 181 THR n 2 182 SER n 2 183 PRO n 2 184 LEU n 2 185 THR n 2 186 VAL n 2 187 GLU n 2 188 TRP n 2 189 ARG n 2 190 ALA n 3 1 GLY n 3 2 GLY n 3 3 VAL n 3 4 TYR n 3 5 HIS n 3 6 PHE n 3 7 VAL n 3 8 LYS n 3 9 LYS n 3 10 HIS n 3 11 VAL n 3 12 HIS n 3 13 GLU n 3 14 SER n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample ? ? ? HUMAN ? ? ? ? ? ? ? ? 'HOMO SAPIENS' 9606 ? ? ? ? ? ? ? ? 'DROSOPHILA MELANOGASTER' 7227 ? ? ? ? ? ? ? ? S2 ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample ? ? ? HUMAN ? ? ? ? ? ? ? ? 'HOMO SAPIENS' 9606 ? ? ? ? ? ? ? ? 'DROSOPHILA MELANOGASTER' 7227 ? ? ? ? ? ? ? ? S2 ? ? ? ? ? ? ? ? ? ? ? ? # _pdbx_entity_src_syn.entity_id 3 _pdbx_entity_src_syn.pdbx_src_id 1 _pdbx_entity_src_syn.pdbx_alt_source_flag sample _pdbx_entity_src_syn.pdbx_beg_seq_num ? _pdbx_entity_src_syn.pdbx_end_seq_num ? _pdbx_entity_src_syn.organism_scientific 'HUMAN HERPESVIRUS 4' _pdbx_entity_src_syn.organism_common_name 'EPSTEIN BARR VIRUS' _pdbx_entity_src_syn.ncbi_taxonomy_id 10376 _pdbx_entity_src_syn.details 'THE PROTEIN OCCURS NATURALLY IN EBV BUT THE PEPTIDE WAS SYNTHESISED CHEMICALLY' # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform 1 UNP HA2R_HUMAN 1 ? ? P01903 ? 2 UNP Q30126 2 ? ? Q30126 ? 3 UNP DPOL_EBV 3 ? ? P03198 ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 1H15 A 1 ? 182 ? P01903 26 ? 207 ? 1 182 2 2 1H15 B 1 ? 190 ? Q30126 30 ? 219 ? 1 190 3 3 1H15 C 1 ? 14 ? P03198 628 ? 641 ? 628 641 4 1 1H15 D 1 ? 182 ? P01903 26 ? 207 ? 1 182 5 2 1H15 E 1 ? 190 ? Q30126 30 ? 219 ? 1 190 6 3 1H15 F 1 ? 14 ? P03198 628 ? 641 ? 628 641 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 1H15 _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.54 _exptl_crystal.density_percent_sol 52 _exptl_crystal.description ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method ? _exptl_crystal_grow.temp ? _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 3.50 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '14% PEG 3550, 100MM GLYCINE AND 10MM TRIS AT PH 3.5-4.0.' # _diffrn.id 1 _diffrn.ambient_temp 293.0 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC CCD' _diffrn_detector.pdbx_collection_date 2001-02-15 _diffrn_detector.details MIRRORS # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'SI111 / SI311 CRYSTALS, LN2 COOLED' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9686 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID14-4' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID14-4 _diffrn_source.pdbx_wavelength 0.9686 _diffrn_source.pdbx_wavelength_list ? # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 1H15 _reflns.observed_criterion_sigma_I ? _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 20.000 _reflns.d_resolution_high 3.100 _reflns.number_obs 28750 _reflns.number_all ? _reflns.percent_possible_obs 94.5 _reflns.pdbx_Rmerge_I_obs 0.41400 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 5.7000 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 6.000 # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 3.10 _reflns_shell.d_res_low 3.30 _reflns_shell.percent_possible_all 78.9 _reflns_shell.Rmerge_I_obs 0.77400 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 1.100 _reflns_shell.pdbx_redundancy 1.60 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 1H15 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 28750 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.0 _refine.pdbx_data_cutoff_high_absF 64350.38 _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 19.88 _refine.ls_d_res_high 3.10 _refine.ls_percent_reflns_obs 93.0 _refine.ls_R_factor_obs 0.256 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.256 _refine.ls_R_factor_R_free 0.310 _refine.ls_R_factor_R_free_error 0.008 _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 4.9 _refine.ls_number_reflns_R_free 1415 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 60.6 _refine.aniso_B[1][1] 2.37 _refine.aniso_B[2][2] 2.37 _refine.aniso_B[3][3] -4.74 _refine.aniso_B[1][2] 12.75 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'FLAT MODEL' _refine.solvent_model_param_ksol 0.3 _refine.solvent_model_param_bsol 80 _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ? _refine.pdbx_starting_model 'SINGLE COPY OF 1FV1 (A AND B CHAINS) MINUS PEPTIDE' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.pdbx_overall_phase_error ? _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_analyze.entry_id 1H15 _refine_analyze.Luzzati_coordinate_error_obs 0.49 _refine_analyze.Luzzati_sigma_a_obs 0.87 _refine_analyze.Luzzati_d_res_low_obs 5.00 _refine_analyze.Luzzati_coordinate_error_free 0.62 _refine_analyze.Luzzati_sigma_a_free 1.07 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6320 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 70 _refine_hist.number_atoms_solvent 30 _refine_hist.number_atoms_total 6420 _refine_hist.d_res_high 3.10 _refine_hist.d_res_low 19.88 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d 0.008 ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg 1.5 ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d 26.1 ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d 0.92 ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it 2.52 2.50 ? ? 'X-RAY DIFFRACTION' ? c_mcangle_it 4.35 3.50 ? ? 'X-RAY DIFFRACTION' ? c_scbond_it 3.54 3.00 ? ? 'X-RAY DIFFRACTION' ? c_scangle_it 5.90 4.50 ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 6 _refine_ls_shell.d_res_high 3.10 _refine_ls_shell.d_res_low 3.29 _refine_ls_shell.number_reflns_R_work 3455 _refine_ls_shell.R_factor_R_work 0.456 _refine_ls_shell.percent_reflns_obs 71.6 _refine_ls_shell.R_factor_R_free 0.479 _refine_ls_shell.R_factor_R_free_error 0.034 _refine_ls_shell.percent_reflns_R_free 5.4 _refine_ls_shell.number_reflns_R_free 197 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? # loop_ _pdbx_xplor_file.pdbx_refine_id _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file 'X-RAY DIFFRACTION' 1 PROTEIN_REP.PARAM PROTEIN.TOP 'X-RAY DIFFRACTION' 2 CARBOHYDRATE.PARAM CARBOHYDRATE.TOP 'X-RAY DIFFRACTION' 3 WATER.PARAM WATER.TOP # _struct.entry_id 1H15 _struct.title 'X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase' _struct.pdbx_descriptor ;HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 1 CHAIN, DNA POLYMERASE (E.C.2.7.7.7) ; _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 1H15 _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM/TRANSFERASE' _struct_keywords.text ;IMMUNE SYSTEM/TRANSFERASE, COMPLEX (MHC-ANTIGEN), IMMUNE SYSTEM, MHC, HLA, CLASS II, DR2, DRB5, EBV, DNA POLYMERASE, DNA-DIRECTED DNA POLYMERASE, IMMUNE SYSTEM-TRANSFERASE complex ; # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 1 ? E N N 2 ? F N N 3 ? G N N 4 ? H N N 4 ? I N N 4 ? J N N 4 ? K N N 4 ? L N N 5 ? M N N 5 ? N N N 5 ? O N N 5 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 LEU A 45 ? PHE A 51 ? LEU A 45 PHE A 51 1 ? 7 HELX_P HELX_P2 2 GLU A 55 ? ARG A 76 ? GLU A 55 ARG A 76 1 ? 22 HELX_P HELX_P3 3 GLN B 64 ? ALA B 73 ? GLN B 64 ALA B 73 1 ? 10 HELX_P HELX_P4 4 ALA B 73 ? TYR B 78 ? ALA B 73 TYR B 78 1 ? 6 HELX_P HELX_P5 5 TYR B 78 ? VAL B 85 ? TYR B 78 VAL B 85 5 ? 8 HELX_P HELX_P6 6 LEU D 45 ? PHE D 51 ? LEU D 45 PHE D 51 1 ? 7 HELX_P HELX_P7 7 GLU D 55 ? ARG D 76 ? GLU D 55 ARG D 76 1 ? 22 HELX_P HELX_P8 8 GLN E 64 ? ALA E 73 ? GLN E 64 ALA E 73 1 ? 10 HELX_P HELX_P9 9 ALA E 73 ? TYR E 78 ? ALA E 73 TYR E 78 1 ? 6 HELX_P HELX_P10 10 TYR E 78 ? VAL E 85 ? TYR E 78 VAL E 85 5 ? 8 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 107 SG ? ? ? 1_555 A CYS 163 SG ? ? A CYS 107 A CYS 163 1_555 ? ? ? ? ? ? ? 2.015 ? disulf2 disulf ? ? B CYS 15 SG ? ? ? 1_555 B CYS 79 SG ? ? B CYS 15 B CYS 79 1_555 ? ? ? ? ? ? ? 2.034 ? disulf3 disulf ? ? B CYS 117 SG ? ? ? 1_555 B CYS 173 SG ? ? B CYS 117 B CYS 173 1_555 ? ? ? ? ? ? ? 2.019 ? disulf4 disulf ? ? D CYS 107 SG ? ? ? 1_555 D CYS 163 SG ? ? D CYS 107 D CYS 163 1_555 ? ? ? ? ? ? ? 2.034 ? disulf5 disulf ? ? E CYS 15 SG ? ? ? 1_555 E CYS 79 SG ? ? E CYS 15 E CYS 79 1_555 ? ? ? ? ? ? ? 2.036 ? disulf6 disulf ? ? E CYS 117 SG ? ? ? 1_555 E CYS 173 SG ? ? E CYS 117 E CYS 173 1_555 ? ? ? ? ? ? ? 2.025 ? covale1 covale ? ? A ASN 78 ND2 ? ? ? 1_555 I NAG . C1 ? ? A ASN 78 A NAG 1185 1_555 ? ? ? ? ? ? ? 1.461 ? covale2 covale ? ? A ASN 118 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 118 A NAG 1183 1_555 ? ? ? ? ? ? ? 1.448 ? covale3 covale ? ? G NAG . O4 ? ? ? 1_555 H NAG . C1 ? ? A NAG 1183 A NAG 1184 1_555 ? ? ? ? ? ? ? 1.391 ? covale4 covale ? ? D ASN 78 ND2 ? ? ? 1_555 K NAG . C1 ? ? D ASN 78 D NAG 1184 1_555 ? ? ? ? ? ? ? 1.456 ? covale5 covale ? ? D ASN 118 ND2 ? ? ? 1_555 J NAG . C1 ? ? D ASN 118 D NAG 1183 1_555 ? ? ? ? ? ? ? 1.451 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ASN 15 A . ? ASN 15 A PRO 16 A ? PRO 16 A 1 0.42 2 THR 113 A . ? THR 113 A PRO 114 A ? PRO 114 A 1 0.33 3 THR 113 D . ? THR 113 D PRO 114 D ? PRO 114 D 1 -0.21 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA ? 8 ? AB ? 2 ? AC ? 4 ? AD ? 4 ? AE ? 4 ? BA ? 4 ? BB ? 4 ? BC ? 3 ? DA ? 8 ? DB ? 2 ? DC ? 4 ? DD ? 4 ? EA ? 4 ? EB ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA 1 2 ? anti-parallel AA 2 3 ? anti-parallel AA 3 4 ? anti-parallel AA 4 5 ? anti-parallel AA 5 6 ? anti-parallel AA 6 7 ? anti-parallel AA 7 8 ? anti-parallel AB 1 2 ? parallel AC 1 2 ? anti-parallel AC 2 3 ? anti-parallel AC 3 4 ? anti-parallel AD 1 2 ? anti-parallel AD 2 3 ? anti-parallel AD 3 4 ? anti-parallel AE 1 2 ? anti-parallel AE 2 3 ? anti-parallel AE 3 4 ? anti-parallel BA 1 2 ? anti-parallel BA 2 3 ? anti-parallel BA 3 4 ? anti-parallel BB 1 2 ? anti-parallel BB 2 3 ? anti-parallel BB 3 4 ? anti-parallel BC 1 2 ? anti-parallel BC 2 3 ? anti-parallel DA 1 2 ? anti-parallel DA 2 3 ? anti-parallel DA 3 4 ? anti-parallel DA 4 5 ? anti-parallel DA 5 6 ? anti-parallel DA 6 7 ? anti-parallel DA 7 8 ? anti-parallel DB 1 2 ? parallel DC 1 2 ? anti-parallel DC 2 3 ? anti-parallel DC 3 4 ? anti-parallel DD 1 2 ? anti-parallel DD 2 3 ? anti-parallel DD 3 4 ? anti-parallel EA 1 2 ? anti-parallel EA 2 3 ? anti-parallel EA 3 4 ? anti-parallel EB 1 2 ? anti-parallel EB 2 3 ? anti-parallel EB 3 4 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA 1 GLU A 40 ? TRP A 43 ? GLU A 40 TRP A 43 AA 2 ASP A 29 ? ASP A 35 ? ASP A 29 ASP A 35 AA 3 SER A 19 ? PHE A 26 ? SER A 19 PHE A 26 AA 4 HIS A 5 ? ASN A 15 ? HIS A 5 ASN A 15 AA 5 PHE B 7 ? PHE B 18 ? PHE B 7 PHE B 18 AA 6 ARG B 23 ? TYR B 32 ? ARG B 23 TYR B 32 AA 7 GLU B 35 ? ASP B 41 ? GLU B 35 ASP B 41 AA 8 TYR B 47 ? ALA B 49 ? TYR B 47 ALA B 49 AB 1 ALA A 52 ? SER A 53 ? ALA A 52 SER A 53 AB 2 GLY C 2 ? VAL C 3 ? GLY C 629 VAL C 630 AC 1 VAL A 89 ? THR A 93 ? VAL A 89 THR A 93 AC 2 ASN A 103 ? PHE A 112 ? ASN A 103 PHE A 112 AC 3 PHE A 145 ? PHE A 153 ? PHE A 145 PHE A 153 AC 4 SER A 133 ? GLU A 134 ? SER A 133 GLU A 134 AD 1 VAL A 89 ? THR A 93 ? VAL A 89 THR A 93 AD 2 ASN A 103 ? PHE A 112 ? ASN A 103 PHE A 112 AD 3 PHE A 145 ? PHE A 153 ? PHE A 145 PHE A 153 AD 4 LEU A 138 ? PRO A 139 ? LEU A 138 PRO A 139 AE 1 LYS A 126 ? VAL A 128 ? LYS A 126 VAL A 128 AE 2 VAL A 117 ? ARG A 123 ? VAL A 117 ARG A 123 AE 3 VAL A 160 ? HIS A 167 ? VAL A 160 HIS A 167 AE 4 LEU A 174 ? GLU A 179 ? LEU A 174 GLU A 179 BA 1 VAL B 101 ? ALA B 104 ? VAL B 101 ALA B 104 BA 2 ASN B 113 ? PHE B 122 ? ASN B 113 PHE B 122 BA 3 PHE B 155 ? THR B 163 ? PHE B 155 THR B 163 BA 4 VAL B 142 ? SER B 144 ? VAL B 142 SER B 144 BB 1 VAL B 101 ? ALA B 104 ? VAL B 101 ALA B 104 BB 2 ASN B 113 ? PHE B 122 ? ASN B 113 PHE B 122 BB 3 PHE B 155 ? THR B 163 ? PHE B 155 THR B 163 BB 4 ILE B 148 ? GLN B 149 ? ILE B 148 GLN B 149 BC 1 GLU B 128 ? ARG B 133 ? GLU B 128 ARG B 133 BC 2 VAL B 170 ? GLU B 176 ? VAL B 170 GLU B 176 BC 3 LEU B 184 ? ARG B 189 ? LEU B 184 ARG B 189 DA 1 GLU D 40 ? TRP D 43 ? GLU D 40 TRP D 43 DA 2 ASP D 29 ? ASP D 35 ? ASP D 29 ASP D 35 DA 3 SER D 19 ? PHE D 26 ? SER D 19 PHE D 26 DA 4 HIS D 5 ? LEU D 14 ? HIS D 5 LEU D 14 DA 5 LEU E 8 ? PHE E 18 ? LEU E 8 PHE E 18 DA 6 ARG E 23 ? TYR E 32 ? ARG E 23 TYR E 32 DA 7 GLU E 35 ? ASP E 41 ? GLU E 35 ASP E 41 DA 8 TYR E 47 ? ALA E 49 ? TYR E 47 ALA E 49 DB 1 ALA D 52 ? SER D 53 ? ALA D 52 SER D 53 DB 2 GLY F 2 ? VAL F 3 ? GLY F 629 VAL F 630 DC 1 GLU D 88 ? THR D 93 ? GLU D 88 THR D 93 DC 2 ASN D 103 ? PHE D 112 ? ASN D 103 PHE D 112 DC 3 PHE D 145 ? PHE D 153 ? PHE D 145 PHE D 153 DC 4 LEU D 138 ? PRO D 139 ? LEU D 138 PRO D 139 DD 1 LYS D 126 ? PRO D 127 ? LYS D 126 PRO D 127 DD 2 THR D 120 ? ARG D 123 ? THR D 120 ARG D 123 DD 3 TYR D 161 ? VAL D 165 ? TYR D 161 VAL D 165 DD 4 LEU D 174 ? TRP D 178 ? LEU D 174 TRP D 178 EA 1 LYS E 98 ? PRO E 103 ? LYS E 98 PRO E 103 EA 2 LEU E 115 ? ASN E 120 ? LEU E 115 ASN E 120 EA 3 GLN E 156 ? LEU E 161 ? GLN E 156 LEU E 161 EA 4 VAL E 142 ? SER E 144 ? VAL E 142 SER E 144 EB 1 GLN E 136 ? GLU E 138 ? GLN E 136 GLU E 138 EB 2 GLU E 128 ? ARG E 133 ? GLU E 128 ARG E 133 EB 3 VAL E 170 ? GLU E 176 ? VAL E 170 GLU E 176 EB 4 LEU E 184 ? ARG E 189 ? LEU E 184 ARG E 189 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA 1 2 N VAL A 42 ? N VAL A 42 O HIS A 33 ? O HIS A 33 AA 2 3 N VAL A 34 ? N VAL A 34 O PHE A 22 ? O PHE A 22 AA 3 4 N ASP A 25 ? N ASP A 25 O ILE A 8 ? O ILE A 8 AA 4 5 N ASN A 15 ? N ASN A 15 O PHE B 7 ? O PHE B 7 AA 5 6 N PHE B 18 ? N PHE B 18 O ARG B 23 ? O ARG B 23 AA 6 7 N TYR B 32 ? N TYR B 32 O GLU B 35 ? O GLU B 35 AA 7 8 N ARG B 39 ? N ARG B 39 O ARG B 48 ? O ARG B 48 AB 1 2 N SER A 53 ? N SER A 53 O GLY C 2 ? O GLY C 629 AC 1 2 N LEU A 92 ? N LEU A 92 O ILE A 106 ? O ILE A 106 AC 2 3 N PHE A 112 ? N PHE A 112 O PHE A 145 ? O PHE A 145 AC 3 4 N TYR A 150 ? N TYR A 150 O SER A 133 ? O SER A 133 AD 1 2 N LEU A 92 ? N LEU A 92 O ILE A 106 ? O ILE A 106 AD 2 3 N PHE A 112 ? N PHE A 112 O PHE A 145 ? O PHE A 145 AD 3 4 N ARG A 146 ? N ARG A 146 O LEU A 138 ? O LEU A 138 AE 1 2 N VAL A 128 ? N VAL A 128 O TRP A 121 ? O TRP A 121 AE 2 3 N LEU A 122 ? N LEU A 122 O ASP A 162 ? O ASP A 162 AE 3 4 N VAL A 165 ? N VAL A 165 O LEU A 174 ? O LEU A 174 BA 1 2 N ALA B 104 ? N ALA B 104 O LEU B 114 ? O LEU B 114 BA 2 3 N GLY B 121 ? N GLY B 121 O PHE B 155 ? O PHE B 155 BA 3 4 N MET B 160 ? N MET B 160 O VAL B 143 ? O VAL B 143 BB 1 2 N ALA B 104 ? N ALA B 104 O LEU B 114 ? O LEU B 114 BB 2 3 N GLY B 121 ? N GLY B 121 O PHE B 155 ? O PHE B 155 BB 3 4 N GLN B 156 ? N GLN B 156 O ILE B 148 ? O ILE B 148 BC 1 2 N PHE B 132 ? N PHE B 132 O THR B 172 ? O THR B 172 BC 2 3 N VAL B 175 ? N VAL B 175 O LEU B 184 ? O LEU B 184 DA 1 2 N VAL D 42 ? N VAL D 42 O HIS D 33 ? O HIS D 33 DA 2 3 N VAL D 34 ? N VAL D 34 O PHE D 22 ? O PHE D 22 DA 3 4 N ASP D 25 ? N ASP D 25 O ILE D 8 ? O ILE D 8 DA 4 5 N TYR D 13 ? N TYR D 13 O GLN E 9 ? O GLN E 9 DA 5 6 N PHE E 18 ? N PHE E 18 O ARG E 23 ? O ARG E 23 DA 6 7 N TYR E 32 ? N TYR E 32 O GLU E 35 ? O GLU E 35 DA 7 8 N ARG E 39 ? N ARG E 39 O ARG E 48 ? O ARG E 48 DB 1 2 N SER D 53 ? N SER D 53 O GLY F 2 ? O GLY F 629 DC 1 2 N LEU D 92 ? N LEU D 92 O ILE D 106 ? O ILE D 106 DC 2 3 N PHE D 112 ? N PHE D 112 O PHE D 145 ? O PHE D 145 DC 3 4 N ARG D 146 ? N ARG D 146 O LEU D 138 ? O LEU D 138 DD 1 2 N LYS D 126 ? N LYS D 126 O ARG D 123 ? O ARG D 123 DD 2 3 N LEU D 122 ? N LEU D 122 O ASP D 162 ? O ASP D 162 DD 3 4 N VAL D 165 ? N VAL D 165 O LEU D 174 ? O LEU D 174 EA 1 2 N TYR E 102 ? N TYR E 102 O VAL E 116 ? O VAL E 116 EA 2 3 N VAL E 119 ? N VAL E 119 O THR E 157 ? O THR E 157 EA 3 4 N MET E 160 ? N MET E 160 O VAL E 143 ? O VAL E 143 EB 1 2 N GLU E 138 ? N GLU E 138 O TRP E 131 ? O TRP E 131 EB 2 3 N PHE E 132 ? N PHE E 132 O THR E 172 ? O THR E 172 EB 3 4 N VAL E 175 ? N VAL E 175 O LEU E 184 ? O LEU E 184 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 1 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 78 RESIDUES 1185 TO 1185' AC2 Software ? ? ? ? 4 'BINDING SITE FOR CHAIN A OF SUGAR BOUND TO ASN A 118 RESIDUES 1183 TO 1184' AC3 Software ? ? ? ? 1 'BINDING SITE FOR CHAIN D OF SUGAR BOUND TO ASN D 78 RESIDUES 1184 TO 1184' AC4 Software ? ? ? ? 3 'BINDING SITE FOR MONO-SACCHARIDE NAG D1183 BOUND TO ASN D 118' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 1 ASN A 78 ? ASN A 78 . ? 1_555 ? 2 AC2 4 ASN A 118 ? ASN A 118 . ? 1_555 ? 3 AC2 4 GLU A 166 ? GLU A 166 . ? 1_555 ? 4 AC2 4 TRP A 168 ? TRP A 168 . ? 1_555 ? 5 AC2 4 ASP B 2 ? ASP B 2 . ? 1_555 ? 6 AC3 1 ASN D 78 ? ASN D 78 . ? 1_555 ? 7 AC4 3 VAL D 117 ? VAL D 117 . ? 1_555 ? 8 AC4 3 ASN D 118 ? ASN D 118 . ? 1_555 ? 9 AC4 3 GLU D 166 ? GLU D 166 . ? 1_555 ? # _database_PDB_matrix.entry_id 1H15 _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 1H15 _atom_sites.fract_transf_matrix[1][1] 0.005579 _atom_sites.fract_transf_matrix[1][2] 0.003221 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.006442 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.010766 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLU A 1 3 ? 112.757 3.068 1.169 1.00 77.99 ? 3 GLU A N 1 ATOM 2 C CA . GLU A 1 3 ? 111.507 2.255 1.319 1.00 75.40 ? 3 GLU A CA 1 ATOM 3 C C . GLU A 1 3 ? 110.874 1.869 -0.025 1.00 72.02 ? 3 GLU A C 1 ATOM 4 O O . GLU A 1 3 ? 111.066 2.539 -1.044 1.00 71.48 ? 3 GLU A O 1 ATOM 5 C CB . GLU A 1 3 ? 110.492 3.015 2.188 1.00 76.07 ? 3 GLU A CB 1 ATOM 6 C CG . GLU A 1 3 ? 109.167 2.290 2.397 1.00 75.56 ? 3 GLU A CG 1 ATOM 7 C CD . GLU A 1 3 ? 108.372 2.858 3.557 1.00 75.99 ? 3 GLU A CD 1 ATOM 8 O OE1 . GLU A 1 3 ? 108.772 2.645 4.723 1.00 74.75 ? 3 GLU A OE1 1 ATOM 9 O OE2 . GLU A 1 3 ? 107.349 3.527 3.305 1.00 76.85 ? 3 GLU A OE2 1 ATOM 10 N N . GLU A 1 4 ? 110.118 0.780 -0.023 1.00 67.12 ? 4 GLU A N 1 ATOM 11 C CA . GLU A 1 4 ? 109.487 0.328 -1.243 1.00 64.42 ? 4 GLU A CA 1 ATOM 12 C C . GLU A 1 4 ? 107.971 0.377 -1.218 1.00 57.50 ? 4 GLU A C 1 ATOM 13 O O . GLU A 1 4 ? 107.350 0.879 -2.150 1.00 57.49 ? 4 GLU A O 1 ATOM 14 C CB . GLU A 1 4 ? 109.940 -1.087 -1.571 1.00 73.14 ? 4 GLU A CB 1 ATOM 15 C CG . GLU A 1 4 ? 111.258 -1.152 -2.302 1.00 83.30 ? 4 GLU A CG 1 ATOM 16 C CD . GLU A 1 4 ? 111.308 -2.334 -3.253 1.00 93.06 ? 4 GLU A CD 1 ATOM 17 O OE1 . GLU A 1 4 ? 111.295 -3.490 -2.769 1.00 95.47 ? 4 GLU A OE1 1 ATOM 18 O OE2 . GLU A 1 4 ? 111.346 -2.103 -4.485 1.00 97.36 ? 4 GLU A OE2 1 ATOM 19 N N . HIS A 1 5 ? 107.368 -0.164 -0.172 1.00 48.50 ? 5 HIS A N 1 ATOM 20 C CA . HIS A 1 5 ? 105.915 -0.155 -0.077 1.00 42.11 ? 5 HIS A CA 1 ATOM 21 C C . HIS A 1 5 ? 105.484 -0.130 1.358 1.00 38.79 ? 5 HIS A C 1 ATOM 22 O O . HIS A 1 5 ? 106.294 -0.321 2.261 1.00 42.82 ? 5 HIS A O 1 ATOM 23 C CB . HIS A 1 5 ? 105.311 -1.402 -0.699 1.00 39.21 ? 5 HIS A CB 1 ATOM 24 C CG . HIS A 1 5 ? 105.579 -1.547 -2.156 1.00 37.40 ? 5 HIS A CG 1 ATOM 25 N ND1 . HIS A 1 5 ? 106.841 -1.438 -2.691 1.00 36.05 ? 5 HIS A ND1 1 ATOM 26 C CD2 . HIS A 1 5 ? 104.760 -1.875 -3.181 1.00 39.54 ? 5 HIS A CD2 1 ATOM 27 C CE1 . HIS A 1 5 ? 106.791 -1.698 -3.984 1.00 41.23 ? 5 HIS A CE1 1 ATOM 28 N NE2 . HIS A 1 5 ? 105.539 -1.968 -4.307 1.00 42.93 ? 5 HIS A NE2 1 ATOM 29 N N . VAL A 1 6 ? 104.195 0.105 1.566 1.00 32.08 ? 6 VAL A N 1 ATOM 30 C CA . VAL A 1 6 ? 103.648 0.116 2.904 1.00 26.28 ? 6 VAL A CA 1 ATOM 31 C C . VAL A 1 6 ? 102.201 -0.252 2.868 1.00 24.25 ? 6 VAL A C 1 ATOM 32 O O . VAL A 1 6 ? 101.426 0.295 2.090 1.00 25.86 ? 6 VAL A O 1 ATOM 33 C CB . VAL A 1 6 ? 103.694 1.463 3.574 1.00 22.87 ? 6 VAL A CB 1 ATOM 34 C CG1 . VAL A 1 6 ? 103.257 1.288 4.997 1.00 24.07 ? 6 VAL A CG1 1 ATOM 35 C CG2 . VAL A 1 6 ? 105.071 2.051 3.506 1.00 24.37 ? 6 VAL A CG2 1 ATOM 36 N N . ILE A 1 7 ? 101.836 -1.194 3.715 1.00 19.85 ? 7 ILE A N 1 ATOM 37 C CA . ILE A 1 7 ? 100.467 -1.597 3.781 1.00 15.31 ? 7 ILE A CA 1 ATOM 38 C C . ILE A 1 7 ? 100.051 -1.199 5.169 1.00 20.10 ? 7 ILE A C 1 ATOM 39 O O . ILE A 1 7 ? 100.763 -1.434 6.149 1.00 18.82 ? 7 ILE A O 1 ATOM 40 C CB . ILE A 1 7 ? 100.306 -3.087 3.559 1.00 7.84 ? 7 ILE A CB 1 ATOM 41 C CG1 . ILE A 1 7 ? 100.908 -3.464 2.207 1.00 5.40 ? 7 ILE A CG1 1 ATOM 42 C CG2 . ILE A 1 7 ? 98.836 -3.442 3.560 1.00 6.68 ? 7 ILE A CG2 1 ATOM 43 C CD1 . ILE A 1 7 ? 100.678 -4.913 1.815 1.00 7.18 ? 7 ILE A CD1 1 ATOM 44 N N . ILE A 1 8 ? 98.894 -0.560 5.244 1.00 25.26 ? 8 ILE A N 1 ATOM 45 C CA . ILE A 1 8 ? 98.396 -0.081 6.512 1.00 23.74 ? 8 ILE A CA 1 ATOM 46 C C . ILE A 1 8 ? 96.983 -0.549 6.778 1.00 24.53 ? 8 ILE A C 1 ATOM 47 O O . ILE A 1 8 ? 96.110 -0.435 5.910 1.00 23.65 ? 8 ILE A O 1 ATOM 48 C CB . ILE A 1 8 ? 98.416 1.475 6.543 1.00 19.66 ? 8 ILE A CB 1 ATOM 49 C CG1 . ILE A 1 8 ? 99.785 1.979 6.086 1.00 18.06 ? 8 ILE A CG1 1 ATOM 50 C CG2 . ILE A 1 8 ? 98.125 1.982 7.936 1.00 18.76 ? 8 ILE A CG2 1 ATOM 51 C CD1 . ILE A 1 8 ? 99.962 3.456 6.150 1.00 10.44 ? 8 ILE A CD1 1 ATOM 52 N N . GLN A 1 9 ? 96.779 -1.121 7.960 1.00 23.61 ? 9 GLN A N 1 ATOM 53 C CA . GLN A 1 9 ? 95.442 -1.513 8.377 1.00 24.19 ? 9 GLN A CA 1 ATOM 54 C C . GLN A 1 9 ? 95.128 -0.262 9.164 1.00 25.36 ? 9 GLN A C 1 ATOM 55 O O . GLN A 1 9 ? 95.773 0.000 10.182 1.00 28.85 ? 9 GLN A O 1 ATOM 56 C CB . GLN A 1 9 ? 95.481 -2.695 9.323 1.00 25.34 ? 9 GLN A CB 1 ATOM 57 C CG . GLN A 1 9 ? 94.114 -3.190 9.721 1.00 24.51 ? 9 GLN A CG 1 ATOM 58 C CD . GLN A 1 9 ? 94.182 -4.024 10.971 1.00 29.48 ? 9 GLN A CD 1 ATOM 59 O OE1 . GLN A 1 9 ? 95.035 -4.901 11.081 1.00 33.51 ? 9 GLN A OE1 1 ATOM 60 N NE2 . GLN A 1 9 ? 93.291 -3.757 11.927 1.00 28.56 ? 9 GLN A NE2 1 ATOM 61 N N . ALA A 1 10 ? 94.182 0.537 8.689 1.00 24.16 ? 10 ALA A N 1 ATOM 62 C CA . ALA A 1 10 ? 93.857 1.789 9.367 1.00 21.24 ? 10 ALA A CA 1 ATOM 63 C C . ALA A 1 10 ? 92.410 1.811 9.807 1.00 21.92 ? 10 ALA A C 1 ATOM 64 O O . ALA A 1 10 ? 91.512 1.471 9.024 1.00 19.32 ? 10 ALA A O 1 ATOM 65 C CB . ALA A 1 10 ? 94.137 2.952 8.447 1.00 16.71 ? 10 ALA A CB 1 ATOM 66 N N . GLU A 1 11 ? 92.188 2.211 11.060 1.00 23.30 ? 11 GLU A N 1 ATOM 67 C CA . GLU A 1 11 ? 90.833 2.271 11.618 1.00 25.70 ? 11 GLU A CA 1 ATOM 68 C C . GLU A 1 11 ? 90.660 3.441 12.586 1.00 21.63 ? 11 GLU A C 1 ATOM 69 O O . GLU A 1 11 ? 91.636 3.938 13.149 1.00 21.83 ? 11 GLU A O 1 ATOM 70 C CB . GLU A 1 11 ? 90.483 0.927 12.305 1.00 31.50 ? 11 GLU A CB 1 ATOM 71 C CG . GLU A 1 11 ? 91.429 0.485 13.435 1.00 34.94 ? 11 GLU A CG 1 ATOM 72 C CD . GLU A 1 11 ? 91.214 -0.965 13.870 1.00 36.98 ? 11 GLU A CD 1 ATOM 73 O OE1 . GLU A 1 11 ? 91.677 -1.342 14.978 1.00 42.82 ? 11 GLU A OE1 1 ATOM 74 O OE2 . GLU A 1 11 ? 90.596 -1.726 13.101 1.00 29.89 ? 11 GLU A OE2 1 ATOM 75 N N . PHE A 1 12 ? 89.422 3.895 12.766 1.00 18.59 ? 12 PHE A N 1 ATOM 76 C CA . PHE A 1 12 ? 89.174 5.011 13.681 1.00 20.63 ? 12 PHE A CA 1 ATOM 77 C C . PHE A 1 12 ? 87.748 5.080 14.209 1.00 20.30 ? 12 PHE A C 1 ATOM 78 O O . PHE A 1 12 ? 86.802 4.712 13.515 1.00 17.38 ? 12 PHE A O 1 ATOM 79 C CB . PHE A 1 12 ? 89.511 6.351 13.002 1.00 20.53 ? 12 PHE A CB 1 ATOM 80 C CG . PHE A 1 12 ? 88.450 6.844 12.023 1.00 18.48 ? 12 PHE A CG 1 ATOM 81 C CD1 . PHE A 1 12 ? 87.243 7.357 12.469 1.00 14.78 ? 12 PHE A CD1 1 ATOM 82 C CD2 . PHE A 1 12 ? 88.674 6.807 10.652 1.00 20.16 ? 12 PHE A CD2 1 ATOM 83 C CE1 . PHE A 1 12 ? 86.294 7.819 11.571 1.00 11.55 ? 12 PHE A CE1 1 ATOM 84 C CE2 . PHE A 1 12 ? 87.718 7.271 9.750 1.00 12.67 ? 12 PHE A CE2 1 ATOM 85 C CZ . PHE A 1 12 ? 86.536 7.774 10.213 1.00 9.04 ? 12 PHE A CZ 1 ATOM 86 N N . TYR A 1 13 ? 87.599 5.553 15.442 1.00 19.65 ? 13 TYR A N 1 ATOM 87 C CA . TYR A 1 13 ? 86.275 5.705 16.008 1.00 25.75 ? 13 TYR A CA 1 ATOM 88 C C . TYR A 1 13 ? 86.133 7.151 16.435 1.00 29.70 ? 13 TYR A C 1 ATOM 89 O O . TYR A 1 13 ? 87.071 7.746 16.968 1.00 32.29 ? 13 TYR A O 1 ATOM 90 C CB . TYR A 1 13 ? 86.059 4.787 17.203 1.00 27.40 ? 13 TYR A CB 1 ATOM 91 C CG . TYR A 1 13 ? 84.591 4.615 17.529 1.00 31.87 ? 13 TYR A CG 1 ATOM 92 C CD1 . TYR A 1 13 ? 83.958 5.418 18.479 1.00 32.84 ? 13 TYR A CD1 1 ATOM 93 C CD2 . TYR A 1 13 ? 83.818 3.673 16.844 1.00 31.74 ? 13 TYR A CD2 1 ATOM 94 C CE1 . TYR A 1 13 ? 82.590 5.282 18.732 1.00 32.75 ? 13 TYR A CE1 1 ATOM 95 C CE2 . TYR A 1 13 ? 82.457 3.531 17.090 1.00 28.39 ? 13 TYR A CE2 1 ATOM 96 C CZ . TYR A 1 13 ? 81.854 4.332 18.027 1.00 31.52 ? 13 TYR A CZ 1 ATOM 97 O OH . TYR A 1 13 ? 80.512 4.168 18.246 1.00 35.95 ? 13 TYR A OH 1 ATOM 98 N N . LEU A 1 14 ? 84.954 7.712 16.198 1.00 30.75 ? 14 LEU A N 1 ATOM 99 C CA . LEU A 1 14 ? 84.691 9.101 16.526 1.00 31.03 ? 14 LEU A CA 1 ATOM 100 C C . LEU A 1 14 ? 83.507 9.316 17.446 1.00 33.33 ? 14 LEU A C 1 ATOM 101 O O . LEU A 1 14 ? 82.372 9.070 17.061 1.00 32.49 ? 14 LEU A O 1 ATOM 102 C CB . LEU A 1 14 ? 84.427 9.892 15.245 1.00 27.74 ? 14 LEU A CB 1 ATOM 103 C CG . LEU A 1 14 ? 84.052 11.357 15.430 1.00 22.54 ? 14 LEU A CG 1 ATOM 104 C CD1 . LEU A 1 14 ? 85.299 12.152 15.747 1.00 18.99 ? 14 LEU A CD1 1 ATOM 105 C CD2 . LEU A 1 14 ? 83.407 11.879 14.183 1.00 20.24 ? 14 LEU A CD2 1 ATOM 106 N N . ASN A 1 15 ? 83.759 9.782 18.662 1.00 36.77 ? 15 ASN A N 1 ATOM 107 C CA . ASN A 1 15 ? 82.656 10.101 19.558 1.00 36.04 ? 15 ASN A CA 1 ATOM 108 C C . ASN A 1 15 ? 82.488 11.621 19.491 1.00 35.69 ? 15 ASN A C 1 ATOM 109 O O . ASN A 1 15 ? 83.456 12.362 19.271 1.00 33.55 ? 15 ASN A O 1 ATOM 110 C CB . ASN A 1 15 ? 82.948 9.652 20.986 1.00 37.07 ? 15 ASN A CB 1 ATOM 111 C CG . ASN A 1 15 ? 82.385 8.280 21.280 1.00 41.94 ? 15 ASN A CG 1 ATOM 112 O OD1 . ASN A 1 15 ? 81.287 7.938 20.826 1.00 44.64 ? 15 ASN A OD1 1 ATOM 113 N ND2 . ASN A 1 15 ? 83.119 7.490 22.054 1.00 41.59 ? 15 ASN A ND2 1 ATOM 114 N N . PRO A 1 16 ? 81.265 12.117 19.704 1.00 34.55 ? 16 PRO A N 1 ATOM 115 C CA . PRO A 1 16 ? 80.005 11.447 20.010 1.00 35.70 ? 16 PRO A CA 1 ATOM 116 C C . PRO A 1 16 ? 79.272 10.885 18.804 1.00 39.09 ? 16 PRO A C 1 ATOM 117 O O . PRO A 1 16 ? 78.301 10.146 18.958 1.00 43.73 ? 16 PRO A O 1 ATOM 118 C CB . PRO A 1 16 ? 79.206 12.560 20.645 1.00 35.66 ? 16 PRO A CB 1 ATOM 119 C CG . PRO A 1 16 ? 79.532 13.695 19.732 1.00 32.14 ? 16 PRO A CG 1 ATOM 120 C CD . PRO A 1 16 ? 81.043 13.568 19.572 1.00 34.55 ? 16 PRO A CD 1 ATOM 121 N N . ASP A 1 17 ? 79.714 11.248 17.607 1.00 38.79 ? 17 ASP A N 1 ATOM 122 C CA . ASP A 1 17 ? 79.059 10.785 16.386 1.00 38.36 ? 17 ASP A CA 1 ATOM 123 C C . ASP A 1 17 ? 78.912 9.262 16.249 1.00 37.92 ? 17 ASP A C 1 ATOM 124 O O . ASP A 1 17 ? 78.106 8.773 15.460 1.00 34.34 ? 17 ASP A O 1 ATOM 125 C CB . ASP A 1 17 ? 79.796 11.368 15.185 1.00 37.27 ? 17 ASP A CB 1 ATOM 126 C CG . ASP A 1 17 ? 79.962 12.861 15.297 1.00 34.33 ? 17 ASP A CG 1 ATOM 127 O OD1 . ASP A 1 17 ? 80.845 13.297 16.056 1.00 33.10 ? 17 ASP A OD1 1 ATOM 128 O OD2 . ASP A 1 17 ? 79.195 13.598 14.645 1.00 35.90 ? 17 ASP A OD2 1 ATOM 129 N N . GLN A 1 18 ? 79.688 8.524 17.033 1.00 40.07 ? 18 GLN A N 1 ATOM 130 C CA . GLN A 1 18 ? 79.653 7.072 17.017 1.00 39.33 ? 18 GLN A CA 1 ATOM 131 C C . GLN A 1 18 ? 79.757 6.478 15.637 1.00 38.66 ? 18 GLN A C 1 ATOM 132 O O . GLN A 1 18 ? 78.961 5.634 15.239 1.00 39.23 ? 18 GLN A O 1 ATOM 133 C CB . GLN A 1 18 ? 78.400 6.571 17.705 1.00 41.71 ? 18 GLN A CB 1 ATOM 134 C CG . GLN A 1 18 ? 78.492 6.716 19.196 1.00 48.27 ? 18 GLN A CG 1 ATOM 135 C CD . GLN A 1 18 ? 77.180 6.451 19.853 1.00 53.86 ? 18 GLN A CD 1 ATOM 136 O OE1 . GLN A 1 18 ? 76.580 5.397 19.650 1.00 56.90 ? 18 GLN A OE1 1 ATOM 137 N NE2 . GLN A 1 18 ? 76.710 7.407 20.647 1.00 57.31 ? 18 GLN A NE2 1 ATOM 138 N N . SER A 1 19 ? 80.765 6.936 14.914 1.00 39.71 ? 19 SER A N 1 ATOM 139 C CA . SER A 1 19 ? 81.045 6.451 13.582 1.00 39.58 ? 19 SER A CA 1 ATOM 140 C C . SER A 1 19 ? 82.510 6.005 13.556 1.00 39.00 ? 19 SER A C 1 ATOM 141 O O . SER A 1 19 ? 83.392 6.652 14.124 1.00 35.71 ? 19 SER A O 1 ATOM 142 C CB . SER A 1 19 ? 80.802 7.549 12.545 1.00 40.56 ? 19 SER A CB 1 ATOM 143 O OG . SER A 1 19 ? 81.771 8.576 12.646 1.00 44.24 ? 19 SER A OG 1 ATOM 144 N N . GLY A 1 20 ? 82.757 4.872 12.914 1.00 40.42 ? 20 GLY A N 1 ATOM 145 C CA . GLY A 1 20 ? 84.109 4.368 12.816 1.00 39.29 ? 20 GLY A CA 1 ATOM 146 C C . GLY A 1 20 ? 84.408 3.984 11.383 1.00 37.02 ? 20 GLY A C 1 ATOM 147 O O . GLY A 1 20 ? 83.629 4.266 10.472 1.00 37.14 ? 20 GLY A O 1 ATOM 148 N N . GLU A 1 21 ? 85.545 3.340 11.179 1.00 34.27 ? 21 GLU A N 1 ATOM 149 C CA . GLU A 1 21 ? 85.923 2.911 9.853 1.00 31.23 ? 21 GLU A CA 1 ATOM 150 C C . GLU A 1 21 ? 87.072 1.925 9.951 1.00 31.99 ? 21 GLU A C 1 ATOM 151 O O . GLU A 1 21 ? 87.952 2.065 10.806 1.00 30.73 ? 21 GLU A O 1 ATOM 152 C CB . GLU A 1 21 ? 86.340 4.108 9.017 1.00 27.01 ? 21 GLU A CB 1 ATOM 153 C CG . GLU A 1 21 ? 86.896 3.714 7.685 1.00 25.29 ? 21 GLU A CG 1 ATOM 154 C CD . GLU A 1 21 ? 87.505 4.878 6.949 1.00 24.94 ? 21 GLU A CD 1 ATOM 155 O OE1 . GLU A 1 21 ? 86.757 5.711 6.392 1.00 28.54 ? 21 GLU A OE1 1 ATOM 156 O OE2 . GLU A 1 21 ? 88.742 4.965 6.931 1.00 22.96 ? 21 GLU A OE2 1 ATOM 157 N N . PHE A 1 22 ? 87.048 0.923 9.077 1.00 30.90 ? 22 PHE A N 1 ATOM 158 C CA . PHE A 1 22 ? 88.086 -0.102 9.031 1.00 27.68 ? 22 PHE A CA 1 ATOM 159 C C . PHE A 1 22 ? 88.428 -0.213 7.564 1.00 26.49 ? 22 PHE A C 1 ATOM 160 O O . PHE A 1 22 ? 87.548 -0.466 6.743 1.00 27.49 ? 22 PHE A O 1 ATOM 161 C CB . PHE A 1 22 ? 87.535 -1.443 9.544 1.00 27.55 ? 22 PHE A CB 1 ATOM 162 C CG . PHE A 1 22 ? 88.577 -2.527 9.707 1.00 23.34 ? 22 PHE A CG 1 ATOM 163 C CD1 . PHE A 1 22 ? 89.118 -3.170 8.603 1.00 19.38 ? 22 PHE A CD1 1 ATOM 164 C CD2 . PHE A 1 22 ? 89.018 -2.902 10.978 1.00 24.35 ? 22 PHE A CD2 1 ATOM 165 C CE1 . PHE A 1 22 ? 90.090 -4.172 8.761 1.00 18.49 ? 22 PHE A CE1 1 ATOM 166 C CE2 . PHE A 1 22 ? 89.989 -3.905 11.148 1.00 18.88 ? 22 PHE A CE2 1 ATOM 167 C CZ . PHE A 1 22 ? 90.524 -4.536 10.040 1.00 15.59 ? 22 PHE A CZ 1 ATOM 168 N N . MET A 1 23 ? 89.693 0.003 7.228 1.00 23.83 ? 23 MET A N 1 ATOM 169 C CA . MET A 1 23 ? 90.114 -0.098 5.838 1.00 24.60 ? 23 MET A CA 1 ATOM 170 C C . MET A 1 23 ? 91.603 -0.403 5.671 1.00 26.13 ? 23 MET A C 1 ATOM 171 O O . MET A 1 23 ? 92.415 -0.061 6.524 1.00 28.83 ? 23 MET A O 1 ATOM 172 C CB . MET A 1 23 ? 89.768 1.192 5.122 1.00 24.07 ? 23 MET A CB 1 ATOM 173 C CG . MET A 1 23 ? 90.501 2.387 5.660 1.00 24.69 ? 23 MET A CG 1 ATOM 174 S SD . MET A 1 23 ? 92.053 2.655 4.803 1.00 24.82 ? 23 MET A SD 1 ATOM 175 C CE . MET A 1 23 ? 91.436 3.385 3.283 1.00 29.37 ? 23 MET A CE 1 ATOM 176 N N . PHE A 1 24 ? 91.949 -1.071 4.577 1.00 28.67 ? 24 PHE A N 1 ATOM 177 C CA . PHE A 1 24 ? 93.334 -1.405 4.279 1.00 33.59 ? 24 PHE A CA 1 ATOM 178 C C . PHE A 1 24 ? 93.842 -0.489 3.181 1.00 37.73 ? 24 PHE A C 1 ATOM 179 O O . PHE A 1 24 ? 93.197 -0.312 2.151 1.00 42.15 ? 24 PHE A O 1 ATOM 180 C CB . PHE A 1 24 ? 93.451 -2.857 3.833 1.00 34.32 ? 24 PHE A CB 1 ATOM 181 C CG . PHE A 1 24 ? 93.735 -3.810 4.953 1.00 34.56 ? 24 PHE A CG 1 ATOM 182 C CD1 . PHE A 1 24 ? 92.753 -4.118 5.886 1.00 31.83 ? 24 PHE A CD1 1 ATOM 183 C CD2 . PHE A 1 24 ? 95.004 -4.378 5.089 1.00 32.46 ? 24 PHE A CD2 1 ATOM 184 C CE1 . PHE A 1 24 ? 93.024 -4.971 6.933 1.00 33.49 ? 24 PHE A CE1 1 ATOM 185 C CE2 . PHE A 1 24 ? 95.289 -5.233 6.131 1.00 32.07 ? 24 PHE A CE2 1 ATOM 186 C CZ . PHE A 1 24 ? 94.300 -5.533 7.058 1.00 36.38 ? 24 PHE A CZ 1 ATOM 187 N N . ASP A 1 25 ? 95.009 0.087 3.396 1.00 40.12 ? 25 ASP A N 1 ATOM 188 C CA . ASP A 1 25 ? 95.563 1.011 2.430 1.00 45.95 ? 25 ASP A CA 1 ATOM 189 C C . ASP A 1 25 ? 96.893 0.478 1.926 1.00 48.46 ? 25 ASP A C 1 ATOM 190 O O . ASP A 1 25 ? 97.746 0.073 2.716 1.00 53.70 ? 25 ASP A O 1 ATOM 191 C CB . ASP A 1 25 ? 95.726 2.374 3.114 1.00 49.72 ? 25 ASP A CB 1 ATOM 192 C CG . ASP A 1 25 ? 96.568 3.346 2.319 1.00 57.02 ? 25 ASP A CG 1 ATOM 193 O OD1 . ASP A 1 25 ? 97.729 3.014 1.986 1.00 59.94 ? 25 ASP A OD1 1 ATOM 194 O OD2 . ASP A 1 25 ? 96.071 4.460 2.044 1.00 62.47 ? 25 ASP A OD2 1 ATOM 195 N N . PHE A 1 26 ? 97.061 0.453 0.610 1.00 46.30 ? 26 PHE A N 1 ATOM 196 C CA . PHE A 1 26 ? 98.307 -0.017 0.020 1.00 43.96 ? 26 PHE A CA 1 ATOM 197 C C . PHE A 1 26 ? 98.986 1.145 -0.695 1.00 44.63 ? 26 PHE A C 1 ATOM 198 O O . PHE A 1 26 ? 98.486 1.643 -1.698 1.00 48.61 ? 26 PHE A O 1 ATOM 199 C CB . PHE A 1 26 ? 98.047 -1.144 -0.983 1.00 40.50 ? 26 PHE A CB 1 ATOM 200 C CG . PHE A 1 26 ? 99.251 -1.498 -1.804 1.00 41.34 ? 26 PHE A CG 1 ATOM 201 C CD1 . PHE A 1 26 ? 100.226 -2.346 -1.304 1.00 41.88 ? 26 PHE A CD1 1 ATOM 202 C CD2 . PHE A 1 26 ? 99.455 -0.915 -3.048 1.00 42.26 ? 26 PHE A CD2 1 ATOM 203 C CE1 . PHE A 1 26 ? 101.388 -2.604 -2.029 1.00 39.73 ? 26 PHE A CE1 1 ATOM 204 C CE2 . PHE A 1 26 ? 100.614 -1.168 -3.773 1.00 42.33 ? 26 PHE A CE2 1 ATOM 205 C CZ . PHE A 1 26 ? 101.580 -2.013 -3.260 1.00 38.24 ? 26 PHE A CZ 1 ATOM 206 N N . ASP A 1 27 ? 100.119 1.591 -0.179 1.00 44.40 ? 27 ASP A N 1 ATOM 207 C CA . ASP A 1 27 ? 100.828 2.684 -0.823 1.00 45.59 ? 27 ASP A CA 1 ATOM 208 C C . ASP A 1 27 ? 99.921 3.851 -1.204 1.00 44.19 ? 27 ASP A C 1 ATOM 209 O O . ASP A 1 27 ? 99.968 4.325 -2.332 1.00 46.04 ? 27 ASP A O 1 ATOM 210 C CB . ASP A 1 27 ? 101.526 2.164 -2.080 1.00 48.85 ? 27 ASP A CB 1 ATOM 211 C CG . ASP A 1 27 ? 102.811 1.430 -1.774 1.00 50.81 ? 27 ASP A CG 1 ATOM 212 O OD1 . ASP A 1 27 ? 102.854 0.697 -0.765 1.00 54.33 ? 27 ASP A OD1 1 ATOM 213 O OD2 . ASP A 1 27 ? 103.775 1.578 -2.553 1.00 50.56 ? 27 ASP A OD2 1 ATOM 214 N N . GLY A 1 28 ? 99.080 4.301 -0.281 1.00 42.99 ? 28 GLY A N 1 ATOM 215 C CA . GLY A 1 28 ? 98.218 5.431 -0.581 1.00 39.37 ? 28 GLY A CA 1 ATOM 216 C C . GLY A 1 28 ? 96.808 5.160 -1.066 1.00 36.81 ? 28 GLY A C 1 ATOM 217 O O . GLY A 1 28 ? 95.905 5.908 -0.705 1.00 38.14 ? 28 GLY A O 1 ATOM 218 N N . ASP A 1 29 ? 96.610 4.129 -1.887 1.00 35.20 ? 29 ASP A N 1 ATOM 219 C CA . ASP A 1 29 ? 95.273 3.802 -2.386 1.00 34.81 ? 29 ASP A CA 1 ATOM 220 C C . ASP A 1 29 ? 94.569 2.793 -1.485 1.00 32.20 ? 29 ASP A C 1 ATOM 221 O O . ASP A 1 29 ? 95.208 2.037 -0.752 1.00 29.98 ? 29 ASP A O 1 ATOM 222 C CB . ASP A 1 29 ? 95.335 3.253 -3.813 1.00 40.11 ? 29 ASP A CB 1 ATOM 223 C CG . ASP A 1 29 ? 95.765 4.299 -4.822 1.00 47.36 ? 29 ASP A CG 1 ATOM 224 O OD1 . ASP A 1 29 ? 94.989 5.238 -5.108 1.00 50.11 ? 29 ASP A OD1 1 ATOM 225 O OD2 . ASP A 1 29 ? 96.894 4.178 -5.331 1.00 53.18 ? 29 ASP A OD2 1 ATOM 226 N N . GLU A 1 30 ? 93.244 2.793 -1.537 1.00 30.79 ? 30 GLU A N 1 ATOM 227 C CA . GLU A 1 30 ? 92.445 1.896 -0.716 1.00 31.39 ? 30 GLU A CA 1 ATOM 228 C C . GLU A 1 30 ? 92.348 0.524 -1.357 1.00 31.69 ? 30 GLU A C 1 ATOM 229 O O . GLU A 1 30 ? 92.146 0.424 -2.560 1.00 36.43 ? 30 GLU A O 1 ATOM 230 C CB . GLU A 1 30 ? 91.032 2.454 -0.553 1.00 30.78 ? 30 GLU A CB 1 ATOM 231 C CG . GLU A 1 30 ? 90.124 1.580 0.292 1.00 36.65 ? 30 GLU A CG 1 ATOM 232 C CD . GLU A 1 30 ? 88.654 1.882 0.080 1.00 42.92 ? 30 GLU A CD 1 ATOM 233 O OE1 . GLU A 1 30 ? 88.320 3.063 -0.149 1.00 48.72 ? 30 GLU A OE1 1 ATOM 234 O OE2 . GLU A 1 30 ? 87.830 0.944 0.153 1.00 42.61 ? 30 GLU A OE2 1 ATOM 235 N N . ILE A 1 31 ? 92.503 -0.535 -0.571 1.00 28.75 ? 31 ILE A N 1 ATOM 236 C CA . ILE A 1 31 ? 92.362 -1.877 -1.118 1.00 26.31 ? 31 ILE A CA 1 ATOM 237 C C . ILE A 1 31 ? 90.898 -2.247 -0.897 1.00 27.93 ? 31 ILE A C 1 ATOM 238 O O . ILE A 1 31 ? 90.195 -2.648 -1.830 1.00 28.60 ? 31 ILE A O 1 ATOM 239 C CB . ILE A 1 31 ? 93.226 -2.903 -0.385 1.00 25.62 ? 31 ILE A CB 1 ATOM 240 C CG1 . ILE A 1 31 ? 94.706 -2.637 -0.631 1.00 24.39 ? 31 ILE A CG1 1 ATOM 241 C CG2 . ILE A 1 31 ? 92.892 -4.288 -0.876 1.00 26.27 ? 31 ILE A CG2 1 ATOM 242 C CD1 . ILE A 1 31 ? 95.609 -3.565 0.148 1.00 17.79 ? 31 ILE A CD1 1 ATOM 243 N N . PHE A 1 32 ? 90.447 -2.102 0.349 1.00 26.62 ? 32 PHE A N 1 ATOM 244 C CA . PHE A 1 32 ? 89.061 -2.394 0.726 1.00 25.30 ? 32 PHE A CA 1 ATOM 245 C C . PHE A 1 32 ? 88.745 -1.771 2.083 1.00 23.95 ? 32 PHE A C 1 ATOM 246 O O . PHE A 1 32 ? 89.606 -1.179 2.721 1.00 25.88 ? 32 PHE A O 1 ATOM 247 C CB . PHE A 1 32 ? 88.820 -3.908 0.815 1.00 23.43 ? 32 PHE A CB 1 ATOM 248 C CG . PHE A 1 32 ? 89.373 -4.537 2.064 1.00 19.73 ? 32 PHE A CG 1 ATOM 249 C CD1 . PHE A 1 32 ? 90.702 -4.903 2.145 1.00 15.53 ? 32 PHE A CD1 1 ATOM 250 C CD2 . PHE A 1 32 ? 88.575 -4.693 3.183 1.00 18.43 ? 32 PHE A CD2 1 ATOM 251 C CE1 . PHE A 1 32 ? 91.222 -5.403 3.317 1.00 15.29 ? 32 PHE A CE1 1 ATOM 252 C CE2 . PHE A 1 32 ? 89.093 -5.193 4.361 1.00 17.58 ? 32 PHE A CE2 1 ATOM 253 C CZ . PHE A 1 32 ? 90.417 -5.547 4.429 1.00 17.45 ? 32 PHE A CZ 1 ATOM 254 N N . HIS A 1 33 ? 87.503 -1.907 2.520 1.00 22.87 ? 33 HIS A N 1 ATOM 255 C CA . HIS A 1 33 ? 87.096 -1.382 3.813 1.00 24.14 ? 33 HIS A CA 1 ATOM 256 C C . HIS A 1 33 ? 85.784 -2.047 4.224 1.00 25.86 ? 33 HIS A C 1 ATOM 257 O O . HIS A 1 33 ? 84.950 -2.380 3.382 1.00 23.52 ? 33 HIS A O 1 ATOM 258 C CB . HIS A 1 33 ? 86.921 0.147 3.762 1.00 22.67 ? 33 HIS A CB 1 ATOM 259 C CG . HIS A 1 33 ? 85.719 0.597 2.993 1.00 21.09 ? 33 HIS A CG 1 ATOM 260 N ND1 . HIS A 1 33 ? 85.733 0.773 1.626 1.00 21.13 ? 33 HIS A ND1 1 ATOM 261 C CD2 . HIS A 1 33 ? 84.448 0.843 3.392 1.00 16.82 ? 33 HIS A CD2 1 ATOM 262 C CE1 . HIS A 1 33 ? 84.521 1.102 1.215 1.00 20.72 ? 33 HIS A CE1 1 ATOM 263 N NE2 . HIS A 1 33 ? 83.723 1.151 2.267 1.00 19.07 ? 33 HIS A NE2 1 ATOM 264 N N . VAL A 1 34 ? 85.608 -2.260 5.517 1.00 26.58 ? 34 VAL A N 1 ATOM 265 C CA . VAL A 1 34 ? 84.389 -2.873 5.986 1.00 30.12 ? 34 VAL A CA 1 ATOM 266 C C . VAL A 1 34 ? 83.310 -1.816 6.134 1.00 33.33 ? 34 VAL A C 1 ATOM 267 O O . VAL A 1 34 ? 83.496 -0.825 6.832 1.00 34.17 ? 34 VAL A O 1 ATOM 268 C CB . VAL A 1 34 ? 84.597 -3.541 7.336 1.00 31.45 ? 34 VAL A CB 1 ATOM 269 C CG1 . VAL A 1 34 ? 83.287 -4.134 7.821 1.00 32.98 ? 34 VAL A CG1 1 ATOM 270 C CG2 . VAL A 1 34 ? 85.664 -4.604 7.222 1.00 31.63 ? 34 VAL A CG2 1 ATOM 271 N N . ASP A 1 35 ? 82.188 -2.029 5.457 1.00 37.75 ? 35 ASP A N 1 ATOM 272 C CA . ASP A 1 35 ? 81.042 -1.127 5.517 1.00 40.06 ? 35 ASP A CA 1 ATOM 273 C C . ASP A 1 35 ? 80.236 -1.476 6.771 1.00 43.99 ? 35 ASP A C 1 ATOM 274 O O . ASP A 1 35 ? 79.443 -2.415 6.766 1.00 42.93 ? 35 ASP A O 1 ATOM 275 C CB . ASP A 1 35 ? 80.170 -1.323 4.284 1.00 38.01 ? 35 ASP A CB 1 ATOM 276 C CG . ASP A 1 35 ? 78.941 -0.458 4.304 1.00 41.85 ? 35 ASP A CG 1 ATOM 277 O OD1 . ASP A 1 35 ? 78.256 -0.423 5.345 1.00 39.50 ? 35 ASP A OD1 1 ATOM 278 O OD2 . ASP A 1 35 ? 78.651 0.184 3.273 1.00 47.66 ? 35 ASP A OD2 1 ATOM 279 N N . MET A 1 36 ? 80.437 -0.718 7.842 1.00 48.17 ? 36 MET A N 1 ATOM 280 C CA . MET A 1 36 ? 79.750 -0.967 9.107 1.00 52.57 ? 36 MET A CA 1 ATOM 281 C C . MET A 1 36 ? 78.288 -1.390 8.993 1.00 54.35 ? 36 MET A C 1 ATOM 282 O O . MET A 1 36 ? 77.935 -2.498 9.381 1.00 56.68 ? 36 MET A O 1 ATOM 283 C CB . MET A 1 36 ? 79.848 0.266 9.989 1.00 55.15 ? 36 MET A CB 1 ATOM 284 C CG . MET A 1 36 ? 81.263 0.754 10.152 1.00 58.80 ? 36 MET A CG 1 ATOM 285 S SD . MET A 1 36 ? 82.294 -0.530 10.835 1.00 59.33 ? 36 MET A SD 1 ATOM 286 C CE . MET A 1 36 ? 81.713 -0.489 12.549 1.00 65.74 ? 36 MET A CE 1 ATOM 287 N N . ALA A 1 37 ? 77.443 -0.504 8.471 1.00 56.43 ? 37 ALA A N 1 ATOM 288 C CA . ALA A 1 37 ? 76.014 -0.774 8.312 1.00 55.85 ? 37 ALA A CA 1 ATOM 289 C C . ALA A 1 37 ? 75.729 -2.105 7.628 1.00 57.46 ? 37 ALA A C 1 ATOM 290 O O . ALA A 1 37 ? 75.272 -3.043 8.268 1.00 59.32 ? 37 ALA A O 1 ATOM 291 C CB . ALA A 1 37 ? 75.357 0.353 7.536 1.00 54.88 ? 37 ALA A CB 1 ATOM 292 N N . LYS A 1 38 ? 75.997 -2.189 6.329 1.00 59.30 ? 38 LYS A N 1 ATOM 293 C CA . LYS A 1 38 ? 75.748 -3.419 5.577 1.00 60.85 ? 38 LYS A CA 1 ATOM 294 C C . LYS A 1 38 ? 76.463 -4.632 6.175 1.00 57.68 ? 38 LYS A C 1 ATOM 295 O O . LYS A 1 38 ? 76.168 -5.774 5.824 1.00 55.67 ? 38 LYS A O 1 ATOM 296 C CB . LYS A 1 38 ? 76.160 -3.234 4.114 1.00 66.31 ? 38 LYS A CB 1 ATOM 297 C CG . LYS A 1 38 ? 75.446 -2.085 3.414 1.00 74.16 ? 38 LYS A CG 1 ATOM 298 C CD . LYS A 1 38 ? 75.933 -1.928 1.977 1.00 83.63 ? 38 LYS A CD 1 ATOM 299 C CE . LYS A 1 38 ? 75.472 -0.608 1.356 1.00 88.28 ? 38 LYS A CE 1 ATOM 300 N NZ . LYS A 1 38 ? 76.071 0.592 2.022 1.00 90.61 ? 38 LYS A NZ 1 ATOM 301 N N . LYS A 1 39 ? 77.408 -4.372 7.073 1.00 56.38 ? 39 LYS A N 1 ATOM 302 C CA . LYS A 1 39 ? 78.153 -5.429 7.748 1.00 55.00 ? 39 LYS A CA 1 ATOM 303 C C . LYS A 1 39 ? 79.020 -6.244 6.791 1.00 52.87 ? 39 LYS A C 1 ATOM 304 O O . LYS A 1 39 ? 79.532 -7.288 7.164 1.00 54.00 ? 39 LYS A O 1 ATOM 305 C CB . LYS A 1 39 ? 77.174 -6.360 8.472 1.00 58.68 ? 39 LYS A CB 1 ATOM 306 C CG . LYS A 1 39 ? 77.634 -6.862 9.836 1.00 63.79 ? 39 LYS A CG 1 ATOM 307 C CD . LYS A 1 39 ? 77.584 -5.769 10.903 1.00 67.82 ? 39 LYS A CD 1 ATOM 308 C CE . LYS A 1 39 ? 76.161 -5.446 11.333 1.00 69.38 ? 39 LYS A CE 1 ATOM 309 N NZ . LYS A 1 39 ? 75.513 -6.611 11.991 1.00 70.86 ? 39 LYS A NZ 1 ATOM 310 N N . GLU A 1 40 ? 79.195 -5.760 5.566 1.00 51.48 ? 40 GLU A N 1 ATOM 311 C CA . GLU A 1 40 ? 79.992 -6.456 4.549 1.00 48.96 ? 40 GLU A CA 1 ATOM 312 C C . GLU A 1 40 ? 81.250 -5.688 4.152 1.00 44.61 ? 40 GLU A C 1 ATOM 313 O O . GLU A 1 40 ? 81.298 -4.470 4.242 1.00 45.27 ? 40 GLU A O 1 ATOM 314 C CB . GLU A 1 40 ? 79.153 -6.658 3.279 1.00 56.30 ? 40 GLU A CB 1 ATOM 315 C CG . GLU A 1 40 ? 78.873 -5.339 2.518 1.00 64.05 ? 40 GLU A CG 1 ATOM 316 C CD . GLU A 1 40 ? 78.025 -5.498 1.248 1.00 68.43 ? 40 GLU A CD 1 ATOM 317 O OE1 . GLU A 1 40 ? 76.834 -5.881 1.350 1.00 69.90 ? 40 GLU A OE1 1 ATOM 318 O OE2 . GLU A 1 40 ? 78.554 -5.225 0.146 1.00 68.96 ? 40 GLU A OE2 1 ATOM 319 N N . THR A 1 41 ? 82.262 -6.400 3.680 1.00 40.54 ? 41 THR A N 1 ATOM 320 C CA . THR A 1 41 ? 83.488 -5.745 3.243 1.00 37.33 ? 41 THR A CA 1 ATOM 321 C C . THR A 1 41 ? 83.338 -5.233 1.801 1.00 36.45 ? 41 THR A C 1 ATOM 322 O O . THR A 1 41 ? 82.712 -5.885 0.968 1.00 36.16 ? 41 THR A O 1 ATOM 323 C CB . THR A 1 41 ? 84.689 -6.709 3.361 1.00 33.78 ? 41 THR A CB 1 ATOM 324 O OG1 . THR A 1 41 ? 85.627 -6.448 2.312 1.00 29.49 ? 41 THR A OG1 1 ATOM 325 C CG2 . THR A 1 41 ? 84.221 -8.140 3.300 1.00 33.01 ? 41 THR A CG2 1 ATOM 326 N N . VAL A 1 42 ? 83.891 -4.051 1.522 1.00 35.62 ? 42 VAL A N 1 ATOM 327 C CA . VAL A 1 42 ? 83.816 -3.438 0.185 1.00 33.47 ? 42 VAL A CA 1 ATOM 328 C C . VAL A 1 42 ? 85.195 -3.280 -0.449 1.00 33.93 ? 42 VAL A C 1 ATOM 329 O O . VAL A 1 42 ? 86.103 -2.737 0.182 1.00 34.74 ? 42 VAL A O 1 ATOM 330 C CB . VAL A 1 42 ? 83.196 -2.027 0.231 1.00 28.11 ? 42 VAL A CB 1 ATOM 331 C CG1 . VAL A 1 42 ? 83.127 -1.457 -1.160 1.00 23.13 ? 42 VAL A CG1 1 ATOM 332 C CG2 . VAL A 1 42 ? 81.824 -2.075 0.847 1.00 30.30 ? 42 VAL A CG2 1 ATOM 333 N N . TRP A 1 43 ? 85.344 -3.732 -1.696 1.00 32.27 ? 43 TRP A N 1 ATOM 334 C CA . TRP A 1 43 ? 86.620 -3.631 -2.407 1.00 30.35 ? 43 TRP A CA 1 ATOM 335 C C . TRP A 1 43 ? 86.615 -2.435 -3.331 1.00 30.45 ? 43 TRP A C 1 ATOM 336 O O . TRP A 1 43 ? 85.608 -2.153 -3.975 1.00 31.42 ? 43 TRP A O 1 ATOM 337 C CB . TRP A 1 43 ? 86.894 -4.891 -3.223 1.00 28.37 ? 43 TRP A CB 1 ATOM 338 C CG . TRP A 1 43 ? 86.953 -6.126 -2.403 1.00 28.55 ? 43 TRP A CG 1 ATOM 339 C CD1 . TRP A 1 43 ? 85.908 -6.926 -2.054 1.00 29.26 ? 43 TRP A CD1 1 ATOM 340 C CD2 . TRP A 1 43 ? 88.109 -6.672 -1.760 1.00 31.35 ? 43 TRP A CD2 1 ATOM 341 N NE1 . TRP A 1 43 ? 86.337 -7.938 -1.228 1.00 32.36 ? 43 TRP A NE1 1 ATOM 342 C CE2 . TRP A 1 43 ? 87.685 -7.806 -1.030 1.00 32.69 ? 43 TRP A CE2 1 ATOM 343 C CE3 . TRP A 1 43 ? 89.462 -6.312 -1.725 1.00 32.24 ? 43 TRP A CE3 1 ATOM 344 C CZ2 . TRP A 1 43 ? 88.566 -8.584 -0.273 1.00 31.67 ? 43 TRP A CZ2 1 ATOM 345 C CZ3 . TRP A 1 43 ? 90.338 -7.084 -0.973 1.00 34.62 ? 43 TRP A CZ3 1 ATOM 346 C CH2 . TRP A 1 43 ? 89.884 -8.208 -0.256 1.00 35.10 ? 43 TRP A CH2 1 ATOM 347 N N . ARG A 1 44 ? 87.744 -1.738 -3.400 1.00 32.17 ? 44 ARG A N 1 ATOM 348 C CA . ARG A 1 44 ? 87.847 -0.549 -4.242 1.00 34.50 ? 44 ARG A CA 1 ATOM 349 C C . ARG A 1 44 ? 87.672 -0.909 -5.703 1.00 35.81 ? 44 ARG A C 1 ATOM 350 O O . ARG A 1 44 ? 87.027 -0.183 -6.462 1.00 36.98 ? 44 ARG A O 1 ATOM 351 C CB . ARG A 1 44 ? 89.201 0.126 -4.055 1.00 31.05 ? 44 ARG A CB 1 ATOM 352 C CG . ARG A 1 44 ? 89.313 1.446 -4.775 1.00 28.42 ? 44 ARG A CG 1 ATOM 353 C CD . ARG A 1 44 ? 88.479 2.515 -4.098 1.00 31.90 ? 44 ARG A CD 1 ATOM 354 N NE . ARG A 1 44 ? 88.579 3.805 -4.777 1.00 31.74 ? 44 ARG A NE 1 ATOM 355 C CZ . ARG A 1 44 ? 87.838 4.159 -5.820 1.00 29.11 ? 44 ARG A CZ 1 ATOM 356 N NH1 . ARG A 1 44 ? 86.932 3.319 -6.302 1.00 23.56 ? 44 ARG A NH1 1 ATOM 357 N NH2 . ARG A 1 44 ? 88.014 5.347 -6.387 1.00 29.46 ? 44 ARG A NH2 1 ATOM 358 N N . LEU A 1 45 ? 88.259 -2.034 -6.089 1.00 36.83 ? 45 LEU A N 1 ATOM 359 C CA . LEU A 1 45 ? 88.173 -2.516 -7.459 1.00 38.48 ? 45 LEU A CA 1 ATOM 360 C C . LEU A 1 45 ? 87.647 -3.940 -7.475 1.00 44.34 ? 45 LEU A C 1 ATOM 361 O O . LEU A 1 45 ? 88.207 -4.816 -6.817 1.00 48.38 ? 45 LEU A O 1 ATOM 362 C CB . LEU A 1 45 ? 89.547 -2.463 -8.123 1.00 29.14 ? 45 LEU A CB 1 ATOM 363 C CG . LEU A 1 45 ? 90.039 -1.045 -8.385 1.00 18.45 ? 45 LEU A CG 1 ATOM 364 C CD1 . LEU A 1 45 ? 91.393 -1.072 -9.058 1.00 11.40 ? 45 LEU A CD1 1 ATOM 365 C CD2 . LEU A 1 45 ? 89.014 -0.338 -9.247 1.00 8.07 ? 45 LEU A CD2 1 ATOM 366 N N . GLU A 1 46 ? 86.567 -4.161 -8.221 1.00 48.16 ? 46 GLU A N 1 ATOM 367 C CA . GLU A 1 46 ? 85.939 -5.474 -8.338 1.00 52.25 ? 46 GLU A CA 1 ATOM 368 C C . GLU A 1 46 ? 86.995 -6.568 -8.381 1.00 52.12 ? 46 GLU A C 1 ATOM 369 O O . GLU A 1 46 ? 86.963 -7.511 -7.595 1.00 50.90 ? 46 GLU A O 1 ATOM 370 C CB . GLU A 1 46 ? 85.106 -5.509 -9.605 1.00 59.83 ? 46 GLU A CB 1 ATOM 371 C CG . GLU A 1 46 ? 84.231 -6.714 -9.758 1.00 69.85 ? 46 GLU A CG 1 ATOM 372 C CD . GLU A 1 46 ? 83.348 -6.588 -10.979 1.00 77.02 ? 46 GLU A CD 1 ATOM 373 O OE1 . GLU A 1 46 ? 83.874 -6.673 -12.118 1.00 78.36 ? 46 GLU A OE1 1 ATOM 374 O OE2 . GLU A 1 46 ? 82.128 -6.385 -10.793 1.00 80.64 ? 46 GLU A OE2 1 ATOM 375 N N . GLU A 1 47 ? 87.930 -6.421 -9.314 1.00 52.91 ? 47 GLU A N 1 ATOM 376 C CA . GLU A 1 47 ? 89.041 -7.346 -9.496 1.00 51.51 ? 47 GLU A CA 1 ATOM 377 C C . GLU A 1 47 ? 89.683 -7.806 -8.177 1.00 51.59 ? 47 GLU A C 1 ATOM 378 O O . GLU A 1 47 ? 89.906 -8.993 -7.979 1.00 52.48 ? 47 GLU A O 1 ATOM 379 C CB . GLU A 1 47 ? 90.087 -6.669 -10.380 1.00 50.10 ? 47 GLU A CB 1 ATOM 380 C CG . GLU A 1 47 ? 91.465 -7.290 -10.358 1.00 50.19 ? 47 GLU A CG 1 ATOM 381 C CD . GLU A 1 47 ? 92.514 -6.337 -10.898 1.00 52.03 ? 47 GLU A CD 1 ATOM 382 O OE1 . GLU A 1 47 ? 93.708 -6.696 -10.905 1.00 53.17 ? 47 GLU A OE1 1 ATOM 383 O OE2 . GLU A 1 47 ? 92.141 -5.221 -11.315 1.00 55.59 ? 47 GLU A OE2 1 ATOM 384 N N . PHE A 1 48 ? 89.980 -6.870 -7.280 1.00 52.24 ? 48 PHE A N 1 ATOM 385 C CA . PHE A 1 48 ? 90.613 -7.206 -6.005 1.00 51.63 ? 48 PHE A CA 1 ATOM 386 C C . PHE A 1 48 ? 89.892 -8.311 -5.256 1.00 54.28 ? 48 PHE A C 1 ATOM 387 O O . PHE A 1 48 ? 90.521 -9.217 -4.716 1.00 54.54 ? 48 PHE A O 1 ATOM 388 C CB . PHE A 1 48 ? 90.684 -5.987 -5.081 1.00 47.16 ? 48 PHE A CB 1 ATOM 389 C CG . PHE A 1 48 ? 91.495 -4.848 -5.618 1.00 42.73 ? 48 PHE A CG 1 ATOM 390 C CD1 . PHE A 1 48 ? 92.560 -5.070 -6.477 1.00 42.26 ? 48 PHE A CD1 1 ATOM 391 C CD2 . PHE A 1 48 ? 91.223 -3.549 -5.216 1.00 42.29 ? 48 PHE A CD2 1 ATOM 392 C CE1 . PHE A 1 48 ? 93.344 -4.013 -6.925 1.00 42.17 ? 48 PHE A CE1 1 ATOM 393 C CE2 . PHE A 1 48 ? 92.003 -2.484 -5.657 1.00 41.88 ? 48 PHE A CE2 1 ATOM 394 C CZ . PHE A 1 48 ? 93.063 -2.716 -6.511 1.00 39.81 ? 48 PHE A CZ 1 ATOM 395 N N . GLY A 1 49 ? 88.568 -8.215 -5.212 1.00 56.69 ? 49 GLY A N 1 ATOM 396 C CA . GLY A 1 49 ? 87.767 -9.199 -4.506 1.00 59.29 ? 49 GLY A CA 1 ATOM 397 C C . GLY A 1 49 ? 87.903 -10.597 -5.057 1.00 60.44 ? 49 GLY A C 1 ATOM 398 O O . GLY A 1 49 ? 88.090 -11.547 -4.305 1.00 61.24 ? 49 GLY A O 1 ATOM 399 N N . ARG A 1 50 ? 87.811 -10.720 -6.376 1.00 62.52 ? 50 ARG A N 1 ATOM 400 C CA . ARG A 1 50 ? 87.926 -12.012 -7.033 1.00 64.31 ? 50 ARG A CA 1 ATOM 401 C C . ARG A 1 50 ? 89.241 -12.734 -6.729 1.00 65.66 ? 50 ARG A C 1 ATOM 402 O O . ARG A 1 50 ? 89.396 -13.903 -7.063 1.00 67.55 ? 50 ARG A O 1 ATOM 403 C CB . ARG A 1 50 ? 87.763 -11.854 -8.554 1.00 61.99 ? 50 ARG A CB 1 ATOM 404 C CG . ARG A 1 50 ? 86.346 -11.521 -9.002 1.00 64.77 ? 50 ARG A CG 1 ATOM 405 C CD . ARG A 1 50 ? 86.139 -11.761 -10.502 1.00 68.17 ? 50 ARG A CD 1 ATOM 406 N NE . ARG A 1 50 ? 85.936 -10.533 -11.279 1.00 70.60 ? 50 ARG A NE 1 ATOM 407 C CZ . ARG A 1 50 ? 86.902 -9.682 -11.625 1.00 72.31 ? 50 ARG A CZ 1 ATOM 408 N NH1 . ARG A 1 50 ? 88.160 -9.912 -11.267 1.00 73.23 ? 50 ARG A NH1 1 ATOM 409 N NH2 . ARG A 1 50 ? 86.611 -8.600 -12.339 1.00 70.97 ? 50 ARG A NH2 1 ATOM 410 N N . PHE A 1 51 ? 90.195 -12.067 -6.093 1.00 66.71 ? 51 PHE A N 1 ATOM 411 C CA . PHE A 1 51 ? 91.447 -12.757 -5.814 1.00 68.03 ? 51 PHE A CA 1 ATOM 412 C C . PHE A 1 51 ? 91.821 -12.843 -4.336 1.00 64.99 ? 51 PHE A C 1 ATOM 413 O O . PHE A 1 51 ? 92.817 -13.469 -3.986 1.00 65.99 ? 51 PHE A O 1 ATOM 414 C CB . PHE A 1 51 ? 92.595 -12.142 -6.637 1.00 75.44 ? 51 PHE A CB 1 ATOM 415 C CG . PHE A 1 51 ? 92.374 -12.201 -8.139 1.00 82.63 ? 51 PHE A CG 1 ATOM 416 C CD1 . PHE A 1 51 ? 91.766 -11.141 -8.816 1.00 86.52 ? 51 PHE A CD1 1 ATOM 417 C CD2 . PHE A 1 51 ? 92.742 -13.330 -8.869 1.00 84.97 ? 51 PHE A CD2 1 ATOM 418 C CE1 . PHE A 1 51 ? 91.524 -11.204 -10.202 1.00 88.52 ? 51 PHE A CE1 1 ATOM 419 C CE2 . PHE A 1 51 ? 92.504 -13.404 -10.254 1.00 88.18 ? 51 PHE A CE2 1 ATOM 420 C CZ . PHE A 1 51 ? 91.893 -12.338 -10.919 1.00 88.66 ? 51 PHE A CZ 1 ATOM 421 N N . ALA A 1 52 ? 91.013 -12.245 -3.465 1.00 60.03 ? 52 ALA A N 1 ATOM 422 C CA . ALA A 1 52 ? 91.295 -12.282 -2.034 1.00 54.69 ? 52 ALA A CA 1 ATOM 423 C C . ALA A 1 52 ? 90.029 -12.058 -1.233 1.00 51.67 ? 52 ALA A C 1 ATOM 424 O O . ALA A 1 52 ? 89.038 -11.574 -1.762 1.00 50.20 ? 52 ALA A O 1 ATOM 425 C CB . ALA A 1 52 ? 92.334 -11.221 -1.674 1.00 53.84 ? 52 ALA A CB 1 ATOM 426 N N . SER A 1 53 ? 90.070 -12.402 0.049 1.00 51.34 ? 53 SER A N 1 ATOM 427 C CA . SER A 1 53 ? 88.909 -12.236 0.907 1.00 54.57 ? 53 SER A CA 1 ATOM 428 C C . SER A 1 53 ? 89.269 -11.764 2.300 1.00 55.57 ? 53 SER A C 1 ATOM 429 O O . SER A 1 53 ? 90.429 -11.832 2.713 1.00 55.22 ? 53 SER A O 1 ATOM 430 C CB . SER A 1 53 ? 88.140 -13.550 1.017 1.00 55.09 ? 53 SER A CB 1 ATOM 431 O OG . SER A 1 53 ? 87.523 -13.879 -0.214 1.00 60.13 ? 53 SER A OG 1 ATOM 432 N N . PHE A 1 54 ? 88.249 -11.293 3.015 1.00 56.77 ? 54 PHE A N 1 ATOM 433 C CA . PHE A 1 54 ? 88.378 -10.794 4.383 1.00 55.90 ? 54 PHE A CA 1 ATOM 434 C C . PHE A 1 54 ? 87.023 -10.958 5.075 1.00 57.66 ? 54 PHE A C 1 ATOM 435 O O . PHE A 1 54 ? 85.978 -10.701 4.474 1.00 56.52 ? 54 PHE A O 1 ATOM 436 C CB . PHE A 1 54 ? 88.760 -9.313 4.371 1.00 49.85 ? 54 PHE A CB 1 ATOM 437 C CG . PHE A 1 54 ? 88.956 -8.733 5.732 1.00 45.51 ? 54 PHE A CG 1 ATOM 438 C CD1 . PHE A 1 54 ? 90.165 -8.886 6.398 1.00 45.22 ? 54 PHE A CD1 1 ATOM 439 C CD2 . PHE A 1 54 ? 87.918 -8.068 6.370 1.00 44.24 ? 54 PHE A CD2 1 ATOM 440 C CE1 . PHE A 1 54 ? 90.340 -8.385 7.691 1.00 43.05 ? 54 PHE A CE1 1 ATOM 441 C CE2 . PHE A 1 54 ? 88.081 -7.564 7.663 1.00 43.01 ? 54 PHE A CE2 1 ATOM 442 C CZ . PHE A 1 54 ? 89.296 -7.725 8.324 1.00 42.31 ? 54 PHE A CZ 1 ATOM 443 N N . GLU A 1 55 ? 87.026 -11.390 6.331 1.00 59.71 ? 55 GLU A N 1 ATOM 444 C CA . GLU A 1 55 ? 85.759 -11.554 7.026 1.00 62.20 ? 55 GLU A CA 1 ATOM 445 C C . GLU A 1 55 ? 85.337 -10.261 7.697 1.00 56.64 ? 55 GLU A C 1 ATOM 446 O O . GLU A 1 55 ? 85.808 -9.910 8.776 1.00 51.64 ? 55 GLU A O 1 ATOM 447 C CB . GLU A 1 55 ? 85.829 -12.682 8.059 1.00 74.47 ? 55 GLU A CB 1 ATOM 448 C CG . GLU A 1 55 ? 84.643 -13.668 7.965 1.00 87.81 ? 55 GLU A CG 1 ATOM 449 C CD . GLU A 1 55 ? 83.271 -13.013 8.196 1.00 95.13 ? 55 GLU A CD 1 ATOM 450 O OE1 . GLU A 1 55 ? 82.847 -12.891 9.368 1.00 95.76 ? 55 GLU A OE1 1 ATOM 451 O OE2 . GLU A 1 55 ? 82.620 -12.616 7.201 1.00 98.82 ? 55 GLU A OE2 1 ATOM 452 N N . ALA A 1 56 ? 84.435 -9.562 7.031 1.00 53.19 ? 56 ALA A N 1 ATOM 453 C CA . ALA A 1 56 ? 83.928 -8.303 7.522 1.00 53.02 ? 56 ALA A CA 1 ATOM 454 C C . ALA A 1 56 ? 83.721 -8.318 9.025 1.00 52.53 ? 56 ALA A C 1 ATOM 455 O O . ALA A 1 56 ? 84.149 -7.410 9.731 1.00 52.98 ? 56 ALA A O 1 ATOM 456 C CB . ALA A 1 56 ? 82.629 -7.976 6.824 1.00 55.20 ? 56 ALA A CB 1 ATOM 457 N N . GLN A 1 57 ? 83.072 -9.356 9.521 1.00 54.03 ? 57 GLN A N 1 ATOM 458 C CA . GLN A 1 57 ? 82.798 -9.435 10.946 1.00 56.90 ? 57 GLN A CA 1 ATOM 459 C C . GLN A 1 57 ? 83.996 -9.090 11.831 1.00 51.41 ? 57 GLN A C 1 ATOM 460 O O . GLN A 1 57 ? 83.933 -8.162 12.625 1.00 48.79 ? 57 GLN A O 1 ATOM 461 C CB . GLN A 1 57 ? 82.253 -10.824 11.293 1.00 67.46 ? 57 GLN A CB 1 ATOM 462 C CG . GLN A 1 57 ? 81.731 -10.958 12.721 1.00 82.42 ? 57 GLN A CG 1 ATOM 463 C CD . GLN A 1 57 ? 82.794 -11.436 13.715 1.00 93.73 ? 57 GLN A CD 1 ATOM 464 O OE1 . GLN A 1 57 ? 83.888 -10.865 13.807 1.00 97.98 ? 57 GLN A OE1 1 ATOM 465 N NE2 . GLN A 1 57 ? 82.467 -12.486 14.472 1.00 97.00 ? 57 GLN A NE2 1 ATOM 466 N N . GLY A 1 58 ? 85.087 -9.830 11.690 1.00 50.17 ? 58 GLY A N 1 ATOM 467 C CA . GLY A 1 58 ? 86.259 -9.575 12.511 1.00 46.93 ? 58 GLY A CA 1 ATOM 468 C C . GLY A 1 58 ? 86.636 -8.111 12.664 1.00 43.47 ? 58 GLY A C 1 ATOM 469 O O . GLY A 1 58 ? 87.202 -7.710 13.682 1.00 41.16 ? 58 GLY A O 1 ATOM 470 N N . ALA A 1 59 ? 86.331 -7.313 11.646 1.00 41.09 ? 59 ALA A N 1 ATOM 471 C CA . ALA A 1 59 ? 86.647 -5.894 11.673 1.00 36.98 ? 59 ALA A CA 1 ATOM 472 C C . ALA A 1 59 ? 85.666 -5.193 12.592 1.00 36.99 ? 59 ALA A C 1 ATOM 473 O O . ALA A 1 59 ? 86.064 -4.385 13.436 1.00 40.65 ? 59 ALA A O 1 ATOM 474 C CB . ALA A 1 59 ? 86.566 -5.314 10.282 1.00 35.86 ? 59 ALA A CB 1 ATOM 475 N N . LEU A 1 60 ? 84.382 -5.498 12.428 1.00 32.37 ? 60 LEU A N 1 ATOM 476 C CA . LEU A 1 60 ? 83.355 -4.906 13.275 1.00 28.72 ? 60 LEU A CA 1 ATOM 477 C C . LEU A 1 60 ? 83.692 -5.148 14.740 1.00 29.44 ? 60 LEU A C 1 ATOM 478 O O . LEU A 1 60 ? 83.192 -4.451 15.615 1.00 30.74 ? 60 LEU A O 1 ATOM 479 C CB . LEU A 1 60 ? 82.009 -5.524 12.960 1.00 26.70 ? 60 LEU A CB 1 ATOM 480 C CG . LEU A 1 60 ? 81.525 -5.142 11.578 1.00 29.62 ? 60 LEU A CG 1 ATOM 481 C CD1 . LEU A 1 60 ? 80.738 -6.278 10.967 1.00 29.61 ? 60 LEU A CD1 1 ATOM 482 C CD2 . LEU A 1 60 ? 80.700 -3.880 11.696 1.00 34.22 ? 60 LEU A CD2 1 ATOM 483 N N . ALA A 1 61 ? 84.537 -6.149 14.985 1.00 29.58 ? 61 ALA A N 1 ATOM 484 C CA . ALA A 1 61 ? 84.983 -6.525 16.323 1.00 25.43 ? 61 ALA A CA 1 ATOM 485 C C . ALA A 1 61 ? 85.993 -5.512 16.843 1.00 26.03 ? 61 ALA A C 1 ATOM 486 O O . ALA A 1 61 ? 85.904 -5.064 17.987 1.00 24.80 ? 61 ALA A O 1 ATOM 487 C CB . ALA A 1 61 ? 85.616 -7.897 16.282 1.00 30.09 ? 61 ALA A CB 1 ATOM 488 N N . ASN A 1 62 ? 86.972 -5.173 16.013 1.00 24.08 ? 62 ASN A N 1 ATOM 489 C CA . ASN A 1 62 ? 87.959 -4.196 16.411 1.00 23.72 ? 62 ASN A CA 1 ATOM 490 C C . ASN A 1 62 ? 87.258 -2.871 16.628 1.00 26.40 ? 62 ASN A C 1 ATOM 491 O O . ASN A 1 62 ? 87.359 -2.281 17.705 1.00 27.95 ? 62 ASN A O 1 ATOM 492 C CB . ASN A 1 62 ? 89.021 -4.022 15.337 1.00 26.63 ? 62 ASN A CB 1 ATOM 493 C CG . ASN A 1 62 ? 90.184 -4.955 15.516 1.00 30.65 ? 62 ASN A CG 1 ATOM 494 O OD1 . ASN A 1 62 ? 90.292 -5.644 16.528 1.00 35.51 ? 62 ASN A OD1 1 ATOM 495 N ND2 . ASN A 1 62 ? 91.078 -4.975 14.536 1.00 32.95 ? 62 ASN A ND2 1 ATOM 496 N N . ILE A 1 63 ? 86.535 -2.405 15.609 1.00 26.28 ? 63 ILE A N 1 ATOM 497 C CA . ILE A 1 63 ? 85.841 -1.122 15.711 1.00 27.82 ? 63 ILE A CA 1 ATOM 498 C C . ILE A 1 63 ? 85.217 -0.919 17.083 1.00 27.29 ? 63 ILE A C 1 ATOM 499 O O . ILE A 1 63 ? 85.298 0.163 17.645 1.00 29.58 ? 63 ILE A O 1 ATOM 500 C CB . ILE A 1 63 ? 84.730 -0.963 14.630 1.00 25.95 ? 63 ILE A CB 1 ATOM 501 C CG1 . ILE A 1 63 ? 85.358 -0.827 13.248 1.00 27.86 ? 63 ILE A CG1 1 ATOM 502 C CG2 . ILE A 1 63 ? 83.920 0.293 14.886 1.00 18.98 ? 63 ILE A CG2 1 ATOM 503 C CD1 . ILE A 1 63 ? 86.243 0.388 13.124 1.00 34.38 ? 63 ILE A CD1 1 ATOM 504 N N . ALA A 1 64 ? 84.621 -1.971 17.629 1.00 28.62 ? 64 ALA A N 1 ATOM 505 C CA . ALA A 1 64 ? 83.961 -1.892 18.930 1.00 29.65 ? 64 ALA A CA 1 ATOM 506 C C . ALA A 1 64 ? 84.932 -1.776 20.098 1.00 29.94 ? 64 ALA A C 1 ATOM 507 O O . ALA A 1 64 ? 84.663 -1.061 21.070 1.00 29.12 ? 64 ALA A O 1 ATOM 508 C CB . ALA A 1 64 ? 83.039 -3.104 19.132 1.00 31.22 ? 64 ALA A CB 1 ATOM 509 N N . VAL A 1 65 ? 86.054 -2.481 20.014 1.00 28.53 ? 65 VAL A N 1 ATOM 510 C CA . VAL A 1 65 ? 87.031 -2.418 21.083 1.00 24.54 ? 65 VAL A CA 1 ATOM 511 C C . VAL A 1 65 ? 87.746 -1.092 20.977 1.00 23.99 ? 65 VAL A C 1 ATOM 512 O O . VAL A 1 65 ? 88.398 -0.654 21.919 1.00 23.35 ? 65 VAL A O 1 ATOM 513 C CB . VAL A 1 65 ? 88.029 -3.559 20.989 1.00 24.78 ? 65 VAL A CB 1 ATOM 514 C CG1 . VAL A 1 65 ? 88.980 -3.486 22.146 1.00 20.33 ? 65 VAL A CG1 1 ATOM 515 C CG2 . VAL A 1 65 ? 87.281 -4.903 20.982 1.00 25.19 ? 65 VAL A CG2 1 ATOM 516 N N . ASP A 1 66 ? 87.614 -0.452 19.817 1.00 24.12 ? 66 ASP A N 1 ATOM 517 C CA . ASP A 1 66 ? 88.207 0.858 19.600 1.00 24.36 ? 66 ASP A CA 1 ATOM 518 C C . ASP A 1 66 ? 87.356 1.865 20.357 1.00 28.04 ? 66 ASP A C 1 ATOM 519 O O . ASP A 1 66 ? 87.879 2.653 21.143 1.00 29.37 ? 66 ASP A O 1 ATOM 520 C CB . ASP A 1 66 ? 88.212 1.219 18.122 1.00 20.21 ? 66 ASP A CB 1 ATOM 521 C CG . ASP A 1 66 ? 89.293 0.507 17.352 1.00 25.83 ? 66 ASP A CG 1 ATOM 522 O OD1 . ASP A 1 66 ? 90.409 0.356 17.888 1.00 32.09 ? 66 ASP A OD1 1 ATOM 523 O OD2 . ASP A 1 66 ? 89.037 0.116 16.195 1.00 26.45 ? 66 ASP A OD2 1 ATOM 524 N N . LYS A 1 67 ? 86.042 1.825 20.121 1.00 30.77 ? 67 LYS A N 1 ATOM 525 C CA . LYS A 1 67 ? 85.103 2.722 20.791 1.00 33.06 ? 67 LYS A CA 1 ATOM 526 C C . LYS A 1 67 ? 85.356 2.675 22.289 1.00 34.39 ? 67 LYS A C 1 ATOM 527 O O . LYS A 1 67 ? 85.209 3.675 22.997 1.00 34.68 ? 67 LYS A O 1 ATOM 528 C CB . LYS A 1 67 ? 83.652 2.301 20.541 1.00 34.00 ? 67 LYS A CB 1 ATOM 529 C CG . LYS A 1 67 ? 82.653 3.195 21.282 1.00 43.87 ? 67 LYS A CG 1 ATOM 530 C CD . LYS A 1 67 ? 81.423 2.450 21.771 1.00 50.03 ? 67 LYS A CD 1 ATOM 531 C CE . LYS A 1 67 ? 80.509 2.082 20.621 1.00 61.33 ? 67 LYS A CE 1 ATOM 532 N NZ . LYS A 1 67 ? 79.330 1.266 21.054 1.00 68.58 ? 67 LYS A NZ 1 ATOM 533 N N . ALA A 1 68 ? 85.724 1.494 22.769 1.00 34.90 ? 68 ALA A N 1 ATOM 534 C CA . ALA A 1 68 ? 86.004 1.301 24.182 1.00 35.00 ? 68 ALA A CA 1 ATOM 535 C C . ALA A 1 68 ? 87.266 2.052 24.550 1.00 35.92 ? 68 ALA A C 1 ATOM 536 O O . ALA A 1 68 ? 87.240 3.040 25.285 1.00 37.84 ? 68 ALA A O 1 ATOM 537 C CB . ALA A 1 68 ? 86.183 -0.165 24.473 1.00 33.47 ? 68 ALA A CB 1 ATOM 538 N N . ASN A 1 69 ? 88.380 1.574 24.022 1.00 36.11 ? 69 ASN A N 1 ATOM 539 C CA . ASN A 1 69 ? 89.659 2.187 24.294 1.00 36.86 ? 69 ASN A CA 1 ATOM 540 C C . ASN A 1 69 ? 89.588 3.693 24.153 1.00 36.97 ? 69 ASN A C 1 ATOM 541 O O . ASN A 1 69 ? 90.315 4.412 24.815 1.00 37.99 ? 69 ASN A O 1 ATOM 542 C CB . ASN A 1 69 ? 90.704 1.649 23.339 1.00 39.40 ? 69 ASN A CB 1 ATOM 543 C CG . ASN A 1 69 ? 92.083 2.100 23.703 1.00 42.36 ? 69 ASN A CG 1 ATOM 544 O OD1 . ASN A 1 69 ? 92.627 1.695 24.731 1.00 45.13 ? 69 ASN A OD1 1 ATOM 545 N ND2 . ASN A 1 69 ? 92.661 2.954 22.874 1.00 44.75 ? 69 ASN A ND2 1 ATOM 546 N N . LEU A 1 70 ? 88.714 4.168 23.277 1.00 38.26 ? 70 LEU A N 1 ATOM 547 C CA . LEU A 1 70 ? 88.554 5.601 23.059 1.00 39.20 ? 70 LEU A CA 1 ATOM 548 C C . LEU A 1 70 ? 88.055 6.291 24.312 1.00 40.45 ? 70 LEU A C 1 ATOM 549 O O . LEU A 1 70 ? 88.646 7.267 24.774 1.00 38.90 ? 70 LEU A O 1 ATOM 550 C CB . LEU A 1 70 ? 87.562 5.859 21.920 1.00 38.70 ? 70 LEU A CB 1 ATOM 551 C CG . LEU A 1 70 ? 87.018 7.280 21.711 1.00 36.80 ? 70 LEU A CG 1 ATOM 552 C CD1 . LEU A 1 70 ? 88.152 8.264 21.509 1.00 34.20 ? 70 LEU A CD1 1 ATOM 553 C CD2 . LEU A 1 70 ? 86.087 7.289 20.505 1.00 36.96 ? 70 LEU A CD2 1 ATOM 554 N N . GLU A 1 71 ? 86.957 5.775 24.855 1.00 42.23 ? 71 GLU A N 1 ATOM 555 C CA . GLU A 1 71 ? 86.361 6.349 26.047 1.00 44.22 ? 71 GLU A CA 1 ATOM 556 C C . GLU A 1 71 ? 87.368 6.348 27.183 1.00 42.29 ? 71 GLU A C 1 ATOM 557 O O . GLU A 1 71 ? 87.442 7.291 27.964 1.00 45.28 ? 71 GLU A O 1 ATOM 558 C CB . GLU A 1 71 ? 85.103 5.573 26.427 1.00 45.07 ? 71 GLU A CB 1 ATOM 559 C CG . GLU A 1 71 ? 84.229 5.266 25.222 1.00 54.90 ? 71 GLU A CG 1 ATOM 560 C CD . GLU A 1 71 ? 82.782 4.998 25.587 1.00 65.52 ? 71 GLU A CD 1 ATOM 561 O OE1 . GLU A 1 71 ? 82.542 4.310 26.606 1.00 71.09 ? 71 GLU A OE1 1 ATOM 562 O OE2 . GLU A 1 71 ? 81.881 5.467 24.848 1.00 68.89 ? 71 GLU A OE2 1 ATOM 563 N N . ILE A 1 72 ? 88.167 5.300 27.270 1.00 38.63 ? 72 ILE A N 1 ATOM 564 C CA . ILE A 1 72 ? 89.157 5.252 28.322 1.00 38.98 ? 72 ILE A CA 1 ATOM 565 C C . ILE A 1 72 ? 90.202 6.326 28.067 1.00 40.92 ? 72 ILE A C 1 ATOM 566 O O . ILE A 1 72 ? 90.667 6.981 28.995 1.00 40.90 ? 72 ILE A O 1 ATOM 567 C CB . ILE A 1 72 ? 89.838 3.874 28.375 1.00 38.25 ? 72 ILE A CB 1 ATOM 568 C CG1 . ILE A 1 72 ? 88.785 2.808 28.678 1.00 40.09 ? 72 ILE A CG1 1 ATOM 569 C CG2 . ILE A 1 72 ? 90.953 3.864 29.421 1.00 34.38 ? 72 ILE A CG2 1 ATOM 570 C CD1 . ILE A 1 72 ? 89.348 1.441 28.918 1.00 39.27 ? 72 ILE A CD1 1 ATOM 571 N N . MET A 1 73 ? 90.550 6.511 26.797 1.00 45.53 ? 73 MET A N 1 ATOM 572 C CA . MET A 1 73 ? 91.562 7.488 26.397 1.00 47.49 ? 73 MET A CA 1 ATOM 573 C C . MET A 1 73 ? 91.017 8.904 26.497 1.00 46.51 ? 73 MET A C 1 ATOM 574 O O . MET A 1 73 ? 91.782 9.857 26.624 1.00 46.45 ? 73 MET A O 1 ATOM 575 C CB . MET A 1 73 ? 92.037 7.207 24.966 1.00 51.25 ? 73 MET A CB 1 ATOM 576 C CG . MET A 1 73 ? 93.458 7.670 24.669 1.00 54.01 ? 73 MET A CG 1 ATOM 577 S SD . MET A 1 73 ? 94.686 6.726 25.581 1.00 57.98 ? 73 MET A SD 1 ATOM 578 C CE . MET A 1 73 ? 95.182 5.550 24.347 1.00 53.14 ? 73 MET A CE 1 ATOM 579 N N . THR A 1 74 ? 89.696 9.046 26.429 1.00 44.91 ? 74 THR A N 1 ATOM 580 C CA . THR A 1 74 ? 89.099 10.367 26.568 1.00 42.13 ? 74 THR A CA 1 ATOM 581 C C . THR A 1 74 ? 89.348 10.759 28.024 1.00 43.81 ? 74 THR A C 1 ATOM 582 O O . THR A 1 74 ? 90.165 11.638 28.302 1.00 43.46 ? 74 THR A O 1 ATOM 583 C CB . THR A 1 74 ? 87.582 10.360 26.300 1.00 37.08 ? 74 THR A CB 1 ATOM 584 O OG1 . THR A 1 74 ? 87.322 9.863 24.987 1.00 34.89 ? 74 THR A OG1 1 ATOM 585 C CG2 . THR A 1 74 ? 87.036 11.757 26.388 1.00 35.31 ? 74 THR A CG2 1 ATOM 586 N N . LYS A 1 75 ? 88.668 10.081 28.949 1.00 44.21 ? 75 LYS A N 1 ATOM 587 C CA . LYS A 1 75 ? 88.832 10.356 30.375 1.00 46.34 ? 75 LYS A CA 1 ATOM 588 C C . LYS A 1 75 ? 90.281 10.630 30.736 1.00 47.43 ? 75 LYS A C 1 ATOM 589 O O . LYS A 1 75 ? 90.616 11.697 31.232 1.00 49.75 ? 75 LYS A O 1 ATOM 590 C CB . LYS A 1 75 ? 88.377 9.173 31.230 1.00 46.57 ? 75 LYS A CB 1 ATOM 591 C CG . LYS A 1 75 ? 86.927 9.157 31.644 1.00 50.21 ? 75 LYS A CG 1 ATOM 592 C CD . LYS A 1 75 ? 86.050 8.530 30.578 1.00 55.97 ? 75 LYS A CD 1 ATOM 593 C CE . LYS A 1 75 ? 84.796 7.926 31.200 1.00 58.29 ? 75 LYS A CE 1 ATOM 594 N NZ . LYS A 1 75 ? 85.168 6.880 32.199 1.00 57.87 ? 75 LYS A NZ 1 ATOM 595 N N . ARG A 1 76 ? 91.136 9.650 30.481 1.00 47.90 ? 76 ARG A N 1 ATOM 596 C CA . ARG A 1 76 ? 92.544 9.753 30.816 1.00 48.93 ? 76 ARG A CA 1 ATOM 597 C C . ARG A 1 76 ? 93.206 11.064 30.404 1.00 48.92 ? 76 ARG A C 1 ATOM 598 O O . ARG A 1 76 ? 94.291 11.377 30.883 1.00 52.22 ? 76 ARG A O 1 ATOM 599 C CB . ARG A 1 76 ? 93.309 8.563 30.220 1.00 52.22 ? 76 ARG A CB 1 ATOM 600 C CG . ARG A 1 76 ? 94.713 8.371 30.777 1.00 54.11 ? 76 ARG A CG 1 ATOM 601 C CD . ARG A 1 76 ? 95.380 7.167 30.150 1.00 58.26 ? 76 ARG A CD 1 ATOM 602 N NE . ARG A 1 76 ? 94.711 5.922 30.514 1.00 65.20 ? 76 ARG A NE 1 ATOM 603 C CZ . ARG A 1 76 ? 95.006 4.735 29.989 1.00 68.50 ? 76 ARG A CZ 1 ATOM 604 N NH1 . ARG A 1 76 ? 95.959 4.638 29.071 1.00 68.00 ? 76 ARG A NH1 1 ATOM 605 N NH2 . ARG A 1 76 ? 94.355 3.644 30.382 1.00 68.79 ? 76 ARG A NH2 1 ATOM 606 N N . SER A 1 77 ? 92.574 11.844 29.537 1.00 47.34 ? 77 SER A N 1 ATOM 607 C CA . SER A 1 77 ? 93.190 13.105 29.131 1.00 49.27 ? 77 SER A CA 1 ATOM 608 C C . SER A 1 77 ? 92.379 14.323 29.553 1.00 51.83 ? 77 SER A C 1 ATOM 609 O O . SER A 1 77 ? 92.576 15.416 29.027 1.00 53.49 ? 77 SER A O 1 ATOM 610 C CB . SER A 1 77 ? 93.387 13.135 27.618 1.00 47.20 ? 77 SER A CB 1 ATOM 611 O OG . SER A 1 77 ? 92.142 13.105 26.951 1.00 45.14 ? 77 SER A OG 1 ATOM 612 N N . ASN A 1 78 ? 91.486 14.132 30.518 1.00 54.08 ? 78 ASN A N 1 ATOM 613 C CA . ASN A 1 78 ? 90.616 15.196 31.012 1.00 55.32 ? 78 ASN A CA 1 ATOM 614 C C . ASN A 1 78 ? 89.827 15.767 29.843 1.00 52.98 ? 78 ASN A C 1 ATOM 615 O O . ASN A 1 78 ? 89.900 16.954 29.545 1.00 55.57 ? 78 ASN A O 1 ATOM 616 C CB . ASN A 1 78 ? 91.423 16.299 31.712 1.00 63.41 ? 78 ASN A CB 1 ATOM 617 C CG . ASN A 1 78 ? 90.543 17.258 32.515 1.00 76.21 ? 78 ASN A CG 1 ATOM 618 O OD1 . ASN A 1 78 ? 89.606 16.829 33.195 1.00 74.36 ? 78 ASN A OD1 1 ATOM 619 N ND2 . ASN A 1 78 ? 90.864 18.553 32.446 1.00 93.09 ? 78 ASN A ND2 1 ATOM 620 N N . TYR A 1 79 ? 89.097 14.884 29.169 1.00 49.69 ? 79 TYR A N 1 ATOM 621 C CA . TYR A 1 79 ? 88.239 15.227 28.044 1.00 44.00 ? 79 TYR A CA 1 ATOM 622 C C . TYR A 1 79 ? 88.681 16.386 27.162 1.00 41.43 ? 79 TYR A C 1 ATOM 623 O O . TYR A 1 79 ? 87.946 17.363 27.021 1.00 42.52 ? 79 TYR A O 1 ATOM 624 C CB . TYR A 1 79 ? 86.841 15.530 28.563 1.00 43.43 ? 79 TYR A CB 1 ATOM 625 C CG . TYR A 1 79 ? 86.118 14.360 29.174 1.00 47.32 ? 79 TYR A CG 1 ATOM 626 C CD1 . TYR A 1 79 ? 85.116 13.706 28.463 1.00 52.86 ? 79 TYR A CD1 1 ATOM 627 C CD2 . TYR A 1 79 ? 86.390 13.939 30.478 1.00 48.66 ? 79 TYR A CD2 1 ATOM 628 C CE1 . TYR A 1 79 ? 84.388 12.664 29.026 1.00 56.83 ? 79 TYR A CE1 1 ATOM 629 C CE2 . TYR A 1 79 ? 85.668 12.893 31.062 1.00 55.64 ? 79 TYR A CE2 1 ATOM 630 C CZ . TYR A 1 79 ? 84.660 12.259 30.322 1.00 60.07 ? 79 TYR A CZ 1 ATOM 631 O OH . TYR A 1 79 ? 83.900 11.235 30.861 1.00 63.48 ? 79 TYR A OH 1 ATOM 632 N N . THR A 1 80 ? 89.871 16.308 26.577 1.00 37.00 ? 80 THR A N 1 ATOM 633 C CA . THR A 1 80 ? 90.288 17.385 25.696 1.00 33.63 ? 80 THR A CA 1 ATOM 634 C C . THR A 1 80 ? 89.879 16.967 24.294 1.00 32.12 ? 80 THR A C 1 ATOM 635 O O . THR A 1 80 ? 90.272 15.912 23.791 1.00 26.63 ? 80 THR A O 1 ATOM 636 C CB . THR A 1 80 ? 91.795 17.641 25.731 1.00 35.20 ? 80 THR A CB 1 ATOM 637 O OG1 . THR A 1 80 ? 92.463 16.692 24.900 1.00 40.14 ? 80 THR A OG1 1 ATOM 638 C CG2 . THR A 1 80 ? 92.312 17.540 27.146 1.00 35.43 ? 80 THR A CG2 1 ATOM 639 N N . PRO A 1 81 ? 89.041 17.785 23.657 1.00 32.46 ? 81 PRO A N 1 ATOM 640 C CA . PRO A 1 81 ? 88.530 17.552 22.314 1.00 32.77 ? 81 PRO A CA 1 ATOM 641 C C . PRO A 1 81 ? 89.556 17.736 21.244 1.00 33.56 ? 81 PRO A C 1 ATOM 642 O O . PRO A 1 81 ? 90.639 18.294 21.459 1.00 31.94 ? 81 PRO A O 1 ATOM 643 C CB . PRO A 1 81 ? 87.412 18.574 22.179 1.00 31.75 ? 81 PRO A CB 1 ATOM 644 C CG . PRO A 1 81 ? 86.989 18.789 23.576 1.00 35.20 ? 81 PRO A CG 1 ATOM 645 C CD . PRO A 1 81 ? 88.298 18.875 24.295 1.00 33.77 ? 81 PRO A CD 1 ATOM 646 N N . ILE A 1 82 ? 89.172 17.268 20.070 1.00 33.09 ? 82 ILE A N 1 ATOM 647 C CA . ILE A 1 82 ? 90.005 17.355 18.901 1.00 32.13 ? 82 ILE A CA 1 ATOM 648 C C . ILE A 1 82 ? 89.982 18.798 18.418 1.00 32.24 ? 82 ILE A C 1 ATOM 649 O O . ILE A 1 82 ? 89.039 19.537 18.687 1.00 37.25 ? 82 ILE A O 1 ATOM 650 C CB . ILE A 1 82 ? 89.463 16.400 17.822 1.00 29.44 ? 82 ILE A CB 1 ATOM 651 C CG1 . ILE A 1 82 ? 90.350 16.455 16.585 1.00 29.89 ? 82 ILE A CG1 1 ATOM 652 C CG2 . ILE A 1 82 ? 87.997 16.719 17.533 1.00 24.35 ? 82 ILE A CG2 1 ATOM 653 C CD1 . ILE A 1 82 ? 90.115 15.324 15.628 1.00 29.87 ? 82 ILE A CD1 1 ATOM 654 N N . THR A 1 83 ? 91.032 19.220 17.736 1.00 31.04 ? 83 THR A N 1 ATOM 655 C CA . THR A 1 83 ? 91.059 20.575 17.223 1.00 31.75 ? 83 THR A CA 1 ATOM 656 C C . THR A 1 83 ? 90.763 20.501 15.734 1.00 31.13 ? 83 THR A C 1 ATOM 657 O O . THR A 1 83 ? 91.530 19.913 14.973 1.00 32.31 ? 83 THR A O 1 ATOM 658 C CB . THR A 1 83 ? 92.428 21.229 17.453 1.00 32.38 ? 83 THR A CB 1 ATOM 659 O OG1 . THR A 1 83 ? 92.617 21.454 18.854 1.00 34.01 ? 83 THR A OG1 1 ATOM 660 C CG2 . THR A 1 83 ? 92.514 22.548 16.723 1.00 34.25 ? 83 THR A CG2 1 ATOM 661 N N . ASN A 1 84 ? 89.642 21.082 15.321 1.00 28.54 ? 84 ASN A N 1 ATOM 662 C CA . ASN A 1 84 ? 89.275 21.061 13.918 1.00 28.53 ? 84 ASN A CA 1 ATOM 663 C C . ASN A 1 84 ? 90.371 21.610 13.025 1.00 28.46 ? 84 ASN A C 1 ATOM 664 O O . ASN A 1 84 ? 91.022 22.594 13.357 1.00 31.69 ? 84 ASN A O 1 ATOM 665 C CB . ASN A 1 84 ? 88.029 21.886 13.676 1.00 29.62 ? 84 ASN A CB 1 ATOM 666 C CG . ASN A 1 84 ? 86.886 21.457 14.524 1.00 34.05 ? 84 ASN A CG 1 ATOM 667 O OD1 . ASN A 1 84 ? 86.605 20.264 14.662 1.00 36.24 ? 84 ASN A OD1 1 ATOM 668 N ND2 . ASN A 1 84 ? 86.193 22.432 15.098 1.00 43.09 ? 84 ASN A ND2 1 ATOM 669 N N . VAL A 1 85 ? 90.559 20.966 11.883 1.00 26.06 ? 85 VAL A N 1 ATOM 670 C CA . VAL A 1 85 ? 91.542 21.387 10.904 1.00 23.99 ? 85 VAL A CA 1 ATOM 671 C C . VAL A 1 85 ? 90.740 21.395 9.624 1.00 23.60 ? 85 VAL A C 1 ATOM 672 O O . VAL A 1 85 ? 90.336 20.343 9.152 1.00 26.39 ? 85 VAL A O 1 ATOM 673 C CB . VAL A 1 85 ? 92.686 20.378 10.789 1.00 22.50 ? 85 VAL A CB 1 ATOM 674 C CG1 . VAL A 1 85 ? 93.702 20.856 9.763 1.00 23.26 ? 85 VAL A CG1 1 ATOM 675 C CG2 . VAL A 1 85 ? 93.340 20.198 12.144 1.00 16.29 ? 85 VAL A CG2 1 ATOM 676 N N . PRO A 1 86 ? 90.500 22.584 9.049 1.00 22.69 ? 86 PRO A N 1 ATOM 677 C CA . PRO A 1 86 ? 89.737 22.836 7.819 1.00 21.40 ? 86 PRO A CA 1 ATOM 678 C C . PRO A 1 86 ? 90.285 22.132 6.599 1.00 20.70 ? 86 PRO A C 1 ATOM 679 O O . PRO A 1 86 ? 91.492 21.978 6.465 1.00 23.72 ? 86 PRO A O 1 ATOM 680 C CB . PRO A 1 86 ? 89.818 24.347 7.657 1.00 22.06 ? 86 PRO A CB 1 ATOM 681 C CG . PRO A 1 86 ? 90.202 24.837 9.011 1.00 27.11 ? 86 PRO A CG 1 ATOM 682 C CD . PRO A 1 86 ? 91.174 23.814 9.477 1.00 23.37 ? 86 PRO A CD 1 ATOM 683 N N . PRO A 1 87 ? 89.402 21.709 5.683 1.00 19.09 ? 87 PRO A N 1 ATOM 684 C CA . PRO A 1 87 ? 89.836 21.024 4.476 1.00 20.99 ? 87 PRO A CA 1 ATOM 685 C C . PRO A 1 87 ? 90.781 21.864 3.651 1.00 24.32 ? 87 PRO A C 1 ATOM 686 O O . PRO A 1 87 ? 91.367 22.844 4.104 1.00 28.91 ? 87 PRO A O 1 ATOM 687 C CB . PRO A 1 87 ? 88.531 20.769 3.726 1.00 17.54 ? 87 PRO A CB 1 ATOM 688 C CG . PRO A 1 87 ? 87.578 20.591 4.790 1.00 20.83 ? 87 PRO A CG 1 ATOM 689 C CD . PRO A 1 87 ? 87.937 21.720 5.745 1.00 22.79 ? 87 PRO A CD 1 ATOM 690 N N . GLU A 1 88 ? 90.891 21.460 2.405 1.00 24.22 ? 88 GLU A N 1 ATOM 691 C CA . GLU A 1 88 ? 91.746 22.094 1.448 1.00 21.85 ? 88 GLU A CA 1 ATOM 692 C C . GLU A 1 88 ? 91.157 21.370 0.271 1.00 22.55 ? 88 GLU A C 1 ATOM 693 O O . GLU A 1 88 ? 91.416 20.192 0.070 1.00 24.73 ? 88 GLU A O 1 ATOM 694 C CB . GLU A 1 88 ? 93.176 21.652 1.693 1.00 21.74 ? 88 GLU A CB 1 ATOM 695 C CG . GLU A 1 88 ? 94.203 22.693 1.405 1.00 28.80 ? 88 GLU A CG 1 ATOM 696 C CD . GLU A 1 88 ? 95.589 22.116 1.448 1.00 35.15 ? 88 GLU A CD 1 ATOM 697 O OE1 . GLU A 1 88 ? 95.899 21.281 0.561 1.00 38.24 ? 88 GLU A OE1 1 ATOM 698 O OE2 . GLU A 1 88 ? 96.357 22.487 2.367 1.00 34.79 ? 88 GLU A OE2 1 ATOM 699 N N . VAL A 1 89 ? 90.317 22.058 -0.479 1.00 21.90 ? 89 VAL A N 1 ATOM 700 C CA . VAL A 1 89 ? 89.678 21.432 -1.605 1.00 18.84 ? 89 VAL A CA 1 ATOM 701 C C . VAL A 1 89 ? 90.272 21.892 -2.927 1.00 22.40 ? 89 VAL A C 1 ATOM 702 O O . VAL A 1 89 ? 90.700 23.037 -3.059 1.00 27.41 ? 89 VAL A O 1 ATOM 703 C CB . VAL A 1 89 ? 88.189 21.739 -1.563 1.00 14.68 ? 89 VAL A CB 1 ATOM 704 C CG1 . VAL A 1 89 ? 87.455 20.935 -2.627 1.00 14.47 ? 89 VAL A CG1 1 ATOM 705 C CG2 . VAL A 1 89 ? 87.657 21.436 -0.171 1.00 11.71 ? 89 VAL A CG2 1 ATOM 706 N N . THR A 1 90 ? 90.328 20.978 -3.890 1.00 24.41 ? 90 THR A N 1 ATOM 707 C CA . THR A 1 90 ? 90.822 21.265 -5.242 1.00 25.77 ? 90 THR A CA 1 ATOM 708 C C . THR A 1 90 ? 89.904 20.493 -6.172 1.00 22.09 ? 90 THR A C 1 ATOM 709 O O . THR A 1 90 ? 89.453 19.405 -5.835 1.00 23.33 ? 90 THR A O 1 ATOM 710 C CB . THR A 1 90 ? 92.284 20.780 -5.479 1.00 28.40 ? 90 THR A CB 1 ATOM 711 O OG1 . THR A 1 90 ? 92.493 19.540 -4.794 1.00 33.01 ? 90 THR A OG1 1 ATOM 712 C CG2 . THR A 1 90 ? 93.301 21.824 -4.998 1.00 27.61 ? 90 THR A CG2 1 ATOM 713 N N . VAL A 1 91 ? 89.591 21.058 -7.324 1.00 19.46 ? 91 VAL A N 1 ATOM 714 C CA . VAL A 1 91 ? 88.721 20.357 -8.245 1.00 20.30 ? 91 VAL A CA 1 ATOM 715 C C . VAL A 1 91 ? 89.427 20.154 -9.554 1.00 23.51 ? 91 VAL A C 1 ATOM 716 O O . VAL A 1 91 ? 89.637 21.101 -10.309 1.00 28.73 ? 91 VAL A O 1 ATOM 717 C CB . VAL A 1 91 ? 87.418 21.120 -8.517 1.00 16.84 ? 91 VAL A CB 1 ATOM 718 C CG1 . VAL A 1 91 ? 86.606 20.397 -9.585 1.00 17.19 ? 91 VAL A CG1 1 ATOM 719 C CG2 . VAL A 1 91 ? 86.610 21.211 -7.257 1.00 18.10 ? 91 VAL A CG2 1 ATOM 720 N N . LEU A 1 92 ? 89.813 18.917 -9.823 1.00 24.30 ? 92 LEU A N 1 ATOM 721 C CA . LEU A 1 92 ? 90.478 18.631 -11.069 1.00 24.86 ? 92 LEU A CA 1 ATOM 722 C C . LEU A 1 92 ? 89.602 17.751 -11.912 1.00 27.93 ? 92 LEU A C 1 ATOM 723 O O . LEU A 1 92 ? 88.597 17.194 -11.452 1.00 26.72 ? 92 LEU A O 1 ATOM 724 C CB . LEU A 1 92 ? 91.831 17.958 -10.844 1.00 23.86 ? 92 LEU A CB 1 ATOM 725 C CG . LEU A 1 92 ? 91.956 16.948 -9.712 1.00 25.56 ? 92 LEU A CG 1 ATOM 726 C CD1 . LEU A 1 92 ? 93.184 16.089 -9.931 1.00 26.99 ? 92 LEU A CD1 1 ATOM 727 C CD2 . LEU A 1 92 ? 92.048 17.687 -8.386 1.00 31.19 ? 92 LEU A CD2 1 ATOM 728 N N . THR A 1 93 ? 89.987 17.656 -13.169 1.00 30.50 ? 93 THR A N 1 ATOM 729 C CA . THR A 1 93 ? 89.268 16.853 -14.108 1.00 33.98 ? 93 THR A CA 1 ATOM 730 C C . THR A 1 93 ? 90.144 15.629 -14.274 1.00 37.44 ? 93 THR A C 1 ATOM 731 O O . THR A 1 93 ? 91.373 15.742 -14.304 1.00 39.05 ? 93 THR A O 1 ATOM 732 C CB . THR A 1 93 ? 89.129 17.608 -15.409 1.00 35.04 ? 93 THR A CB 1 ATOM 733 O OG1 . THR A 1 93 ? 88.456 16.782 -16.357 1.00 44.41 ? 93 THR A OG1 1 ATOM 734 C CG2 . THR A 1 93 ? 90.495 18.018 -15.931 1.00 28.88 ? 93 THR A CG2 1 ATOM 735 N N . ASN A 1 94 ? 89.514 14.462 -14.351 1.00 40.36 ? 94 ASN A N 1 ATOM 736 C CA . ASN A 1 94 ? 90.230 13.195 -14.491 1.00 42.53 ? 94 ASN A CA 1 ATOM 737 C C . ASN A 1 94 ? 91.227 13.115 -15.643 1.00 43.78 ? 94 ASN A C 1 ATOM 738 O O . ASN A 1 94 ? 92.370 12.689 -15.471 1.00 44.68 ? 94 ASN A O 1 ATOM 739 C CB . ASN A 1 94 ? 89.245 12.057 -14.656 1.00 41.23 ? 94 ASN A CB 1 ATOM 740 C CG . ASN A 1 94 ? 89.885 10.852 -15.275 1.00 41.17 ? 94 ASN A CG 1 ATOM 741 O OD1 . ASN A 1 94 ? 90.786 10.247 -14.694 1.00 44.61 ? 94 ASN A OD1 1 ATOM 742 N ND2 . ASN A 1 94 ? 89.443 10.504 -16.473 1.00 40.56 ? 94 ASN A ND2 1 ATOM 743 N N . SER A 1 95 ? 90.773 13.476 -16.832 1.00 42.76 ? 95 SER A N 1 ATOM 744 C CA . SER A 1 95 ? 91.640 13.459 -17.994 1.00 44.51 ? 95 SER A CA 1 ATOM 745 C C . SER A 1 95 ? 91.391 14.763 -18.738 1.00 43.47 ? 95 SER A C 1 ATOM 746 O O . SER A 1 95 ? 90.428 15.464 -18.432 1.00 42.99 ? 95 SER A O 1 ATOM 747 C CB . SER A 1 95 ? 91.317 12.250 -18.877 1.00 46.77 ? 95 SER A CB 1 ATOM 748 O OG . SER A 1 95 ? 89.933 12.177 -19.172 1.00 52.74 ? 95 SER A OG 1 ATOM 749 N N . PRO A 1 96 ? 92.264 15.123 -19.696 1.00 41.06 ? 96 PRO A N 1 ATOM 750 C CA . PRO A 1 96 ? 92.083 16.360 -20.448 1.00 40.01 ? 96 PRO A CA 1 ATOM 751 C C . PRO A 1 96 ? 90.678 16.486 -21.019 1.00 40.34 ? 96 PRO A C 1 ATOM 752 O O . PRO A 1 96 ? 90.229 15.654 -21.813 1.00 38.85 ? 96 PRO A O 1 ATOM 753 C CB . PRO A 1 96 ? 93.161 16.259 -21.502 1.00 39.60 ? 96 PRO A CB 1 ATOM 754 C CG . PRO A 1 96 ? 94.273 15.669 -20.719 1.00 39.93 ? 96 PRO A CG 1 ATOM 755 C CD . PRO A 1 96 ? 93.571 14.531 -20.018 1.00 41.91 ? 96 PRO A CD 1 ATOM 756 N N . VAL A 1 97 ? 90.000 17.547 -20.586 1.00 40.09 ? 97 VAL A N 1 ATOM 757 C CA . VAL A 1 97 ? 88.628 17.839 -20.973 1.00 39.43 ? 97 VAL A CA 1 ATOM 758 C C . VAL A 1 97 ? 88.449 18.330 -22.387 1.00 37.80 ? 97 VAL A C 1 ATOM 759 O O . VAL A 1 97 ? 88.935 19.388 -22.748 1.00 39.83 ? 97 VAL A O 1 ATOM 760 C CB . VAL A 1 97 ? 87.988 18.894 -20.016 1.00 40.39 ? 97 VAL A CB 1 ATOM 761 C CG1 . VAL A 1 97 ? 88.936 20.068 -19.807 1.00 41.46 ? 97 VAL A CG1 1 ATOM 762 C CG2 . VAL A 1 97 ? 86.673 19.391 -20.589 1.00 37.09 ? 97 VAL A CG2 1 ATOM 763 N N . GLU A 1 98 ? 87.758 17.550 -23.199 1.00 37.07 ? 98 GLU A N 1 ATOM 764 C CA . GLU A 1 98 ? 87.488 17.989 -24.546 1.00 38.25 ? 98 GLU A CA 1 ATOM 765 C C . GLU A 1 98 ? 86.006 17.829 -24.796 1.00 37.91 ? 98 GLU A C 1 ATOM 766 O O . GLU A 1 98 ? 85.393 16.835 -24.403 1.00 32.45 ? 98 GLU A O 1 ATOM 767 C CB . GLU A 1 98 ? 88.320 17.229 -25.573 1.00 41.82 ? 98 GLU A CB 1 ATOM 768 C CG . GLU A 1 98 ? 88.394 15.741 -25.414 1.00 48.06 ? 98 GLU A CG 1 ATOM 769 C CD . GLU A 1 98 ? 89.125 15.111 -26.583 1.00 53.37 ? 98 GLU A CD 1 ATOM 770 O OE1 . GLU A 1 98 ? 88.532 15.016 -27.681 1.00 53.50 ? 98 GLU A OE1 1 ATOM 771 O OE2 . GLU A 1 98 ? 90.302 14.733 -26.409 1.00 58.80 ? 98 GLU A OE2 1 ATOM 772 N N . LEU A 1 99 ? 85.435 18.842 -25.433 1.00 39.29 ? 99 LEU A N 1 ATOM 773 C CA . LEU A 1 99 ? 84.017 18.873 -25.709 1.00 41.61 ? 99 LEU A CA 1 ATOM 774 C C . LEU A 1 99 ? 83.332 17.577 -26.091 1.00 43.42 ? 99 LEU A C 1 ATOM 775 O O . LEU A 1 99 ? 83.877 16.749 -26.810 1.00 45.01 ? 99 LEU A O 1 ATOM 776 C CB . LEU A 1 99 ? 83.735 19.936 -26.747 1.00 41.60 ? 99 LEU A CB 1 ATOM 777 C CG . LEU A 1 99 ? 83.176 21.148 -26.018 1.00 45.58 ? 99 LEU A CG 1 ATOM 778 C CD1 . LEU A 1 99 ? 83.732 22.416 -26.619 1.00 48.06 ? 99 LEU A CD1 1 ATOM 779 C CD2 . LEU A 1 99 ? 81.643 21.100 -26.078 1.00 49.93 ? 99 LEU A CD2 1 ATOM 780 N N . ARG A 1 100 ? 82.122 17.421 -25.571 1.00 45.85 ? 100 ARG A N 1 ATOM 781 C CA . ARG A 1 100 ? 81.277 16.259 -25.810 1.00 47.28 ? 100 ARG A CA 1 ATOM 782 C C . ARG A 1 100 ? 81.968 14.902 -25.661 1.00 44.76 ? 100 ARG A C 1 ATOM 783 O O . ARG A 1 100 ? 81.523 13.896 -26.212 1.00 45.34 ? 100 ARG A O 1 ATOM 784 C CB . ARG A 1 100 ? 80.629 16.393 -27.186 1.00 52.63 ? 100 ARG A CB 1 ATOM 785 C CG . ARG A 1 100 ? 79.987 17.759 -27.401 1.00 63.75 ? 100 ARG A CG 1 ATOM 786 C CD . ARG A 1 100 ? 78.743 17.664 -28.275 1.00 76.25 ? 100 ARG A CD 1 ATOM 787 N NE . ARG A 1 100 ? 77.682 16.830 -27.686 1.00 84.38 ? 100 ARG A NE 1 ATOM 788 C CZ . ARG A 1 100 ? 76.978 17.137 -26.594 1.00 85.38 ? 100 ARG A CZ 1 ATOM 789 N NH1 . ARG A 1 100 ? 77.208 18.270 -25.937 1.00 86.59 ? 100 ARG A NH1 1 ATOM 790 N NH2 . ARG A 1 100 ? 76.031 16.310 -26.161 1.00 82.44 ? 100 ARG A NH2 1 ATOM 791 N N . GLU A 1 101 ? 83.045 14.866 -24.893 1.00 42.22 ? 101 GLU A N 1 ATOM 792 C CA . GLU A 1 101 ? 83.758 13.617 -24.691 1.00 40.44 ? 101 GLU A CA 1 ATOM 793 C C . GLU A 1 101 ? 83.758 13.296 -23.207 1.00 38.04 ? 101 GLU A C 1 ATOM 794 O O . GLU A 1 101 ? 84.346 14.023 -22.415 1.00 41.03 ? 101 GLU A O 1 ATOM 795 C CB . GLU A 1 101 ? 85.193 13.748 -25.192 1.00 40.39 ? 101 GLU A CB 1 ATOM 796 C CG . GLU A 1 101 ? 85.703 12.549 -25.968 1.00 40.39 ? 101 GLU A CG 1 ATOM 797 C CD . GLU A 1 101 ? 84.917 12.301 -27.243 1.00 39.98 ? 101 GLU A CD 1 ATOM 798 O OE1 . GLU A 1 101 ? 83.885 11.587 -27.198 1.00 39.29 ? 101 GLU A OE1 1 ATOM 799 O OE2 . GLU A 1 101 ? 85.335 12.835 -28.291 1.00 40.07 ? 101 GLU A OE2 1 ATOM 800 N N . PRO A 1 102 ? 83.103 12.193 -22.815 1.00 34.71 ? 102 PRO A N 1 ATOM 801 C CA . PRO A 1 102 ? 82.994 11.731 -21.428 1.00 31.02 ? 102 PRO A CA 1 ATOM 802 C C . PRO A 1 102 ? 84.226 12.010 -20.583 1.00 30.05 ? 102 PRO A C 1 ATOM 803 O O . PRO A 1 102 ? 85.355 11.964 -21.075 1.00 33.61 ? 102 PRO A O 1 ATOM 804 C CB . PRO A 1 102 ? 82.754 10.243 -21.587 1.00 29.16 ? 102 PRO A CB 1 ATOM 805 C CG . PRO A 1 102 ? 81.922 10.189 -22.797 1.00 34.38 ? 102 PRO A CG 1 ATOM 806 C CD . PRO A 1 102 ? 82.580 11.175 -23.741 1.00 33.48 ? 102 PRO A CD 1 ATOM 807 N N . ASN A 1 103 ? 84.006 12.290 -19.305 1.00 27.19 ? 103 ASN A N 1 ATOM 808 C CA . ASN A 1 103 ? 85.103 12.561 -18.385 1.00 25.42 ? 103 ASN A CA 1 ATOM 809 C C . ASN A 1 103 ? 84.590 12.536 -16.936 1.00 26.03 ? 103 ASN A C 1 ATOM 810 O O . ASN A 1 103 ? 83.422 12.225 -16.688 1.00 27.30 ? 103 ASN A O 1 ATOM 811 C CB . ASN A 1 103 ? 85.708 13.920 -18.705 1.00 22.67 ? 103 ASN A CB 1 ATOM 812 C CG . ASN A 1 103 ? 87.140 14.038 -18.261 1.00 22.45 ? 103 ASN A CG 1 ATOM 813 O OD1 . ASN A 1 103 ? 87.477 13.774 -17.106 1.00 20.99 ? 103 ASN A OD1 1 ATOM 814 N ND2 . ASN A 1 103 ? 88.000 14.451 -19.180 1.00 22.43 ? 103 ASN A ND2 1 ATOM 815 N N . VAL A 1 104 ? 85.458 12.849 -15.981 1.00 23.69 ? 104 VAL A N 1 ATOM 816 C CA . VAL A 1 104 ? 85.057 12.858 -14.581 1.00 23.33 ? 104 VAL A CA 1 ATOM 817 C C . VAL A 1 104 ? 85.667 14.035 -13.826 1.00 26.11 ? 104 VAL A C 1 ATOM 818 O O . VAL A 1 104 ? 86.816 14.437 -14.065 1.00 26.32 ? 104 VAL A O 1 ATOM 819 C CB . VAL A 1 104 ? 85.463 11.549 -13.834 1.00 20.51 ? 104 VAL A CB 1 ATOM 820 C CG1 . VAL A 1 104 ? 84.245 10.903 -13.233 1.00 22.46 ? 104 VAL A CG1 1 ATOM 821 C CG2 . VAL A 1 104 ? 86.130 10.578 -14.766 1.00 22.37 ? 104 VAL A CG2 1 ATOM 822 N N . LEU A 1 105 ? 84.873 14.603 -12.926 1.00 26.06 ? 105 LEU A N 1 ATOM 823 C CA . LEU A 1 105 ? 85.331 15.708 -12.107 1.00 25.77 ? 105 LEU A CA 1 ATOM 824 C C . LEU A 1 105 ? 85.688 15.063 -10.775 1.00 26.81 ? 105 LEU A C 1 ATOM 825 O O . LEU A 1 105 ? 84.943 14.220 -10.260 1.00 26.16 ? 105 LEU A O 1 ATOM 826 C CB . LEU A 1 105 ? 84.220 16.760 -11.926 1.00 25.23 ? 105 LEU A CB 1 ATOM 827 C CG . LEU A 1 105 ? 84.039 17.851 -12.995 1.00 22.62 ? 105 LEU A CG 1 ATOM 828 C CD1 . LEU A 1 105 ? 82.850 18.721 -12.635 1.00 20.97 ? 105 LEU A CD1 1 ATOM 829 C CD2 . LEU A 1 105 ? 85.300 18.698 -13.107 1.00 17.29 ? 105 LEU A CD2 1 ATOM 830 N N . ILE A 1 106 ? 86.841 15.434 -10.233 1.00 24.50 ? 106 ILE A N 1 ATOM 831 C CA . ILE A 1 106 ? 87.281 14.880 -8.964 1.00 23.26 ? 106 ILE A CA 1 ATOM 832 C C . ILE A 1 106 ? 87.348 16.020 -7.962 1.00 25.40 ? 106 ILE A C 1 ATOM 833 O O . ILE A 1 106 ? 88.112 16.966 -8.160 1.00 25.33 ? 106 ILE A O 1 ATOM 834 C CB . ILE A 1 106 ? 88.708 14.293 -9.055 1.00 21.35 ? 106 ILE A CB 1 ATOM 835 C CG1 . ILE A 1 106 ? 88.871 13.448 -10.306 1.00 23.19 ? 106 ILE A CG1 1 ATOM 836 C CG2 . ILE A 1 106 ? 88.990 13.425 -7.866 1.00 19.87 ? 106 ILE A CG2 1 ATOM 837 C CD1 . ILE A 1 106 ? 90.334 13.235 -10.690 1.00 24.13 ? 106 ILE A CD1 1 ATOM 838 N N . CYS A 1 107 ? 86.535 15.964 -6.911 1.00 23.94 ? 107 CYS A N 1 ATOM 839 C CA . CYS A 1 107 ? 86.617 16.990 -5.885 1.00 19.18 ? 107 CYS A CA 1 ATOM 840 C C . CYS A 1 107 ? 87.523 16.334 -4.848 1.00 17.48 ? 107 CYS A C 1 ATOM 841 O O . CYS A 1 107 ? 87.128 15.410 -4.145 1.00 17.14 ? 107 CYS A O 1 ATOM 842 C CB . CYS A 1 107 ? 85.253 17.303 -5.285 1.00 16.63 ? 107 CYS A CB 1 ATOM 843 S SG . CYS A 1 107 ? 85.349 18.698 -4.124 1.00 17.23 ? 107 CYS A SG 1 ATOM 844 N N . PHE A 1 108 ? 88.753 16.809 -4.775 1.00 14.40 ? 108 PHE A N 1 ATOM 845 C CA . PHE A 1 108 ? 89.745 16.244 -3.883 1.00 15.23 ? 108 PHE A CA 1 ATOM 846 C C . PHE A 1 108 ? 89.961 17.038 -2.587 1.00 16.06 ? 108 PHE A C 1 ATOM 847 O O . PHE A 1 108 ? 90.699 18.025 -2.575 1.00 18.89 ? 108 PHE A O 1 ATOM 848 C CB . PHE A 1 108 ? 91.042 16.083 -4.707 1.00 12.66 ? 108 PHE A CB 1 ATOM 849 C CG . PHE A 1 108 ? 92.283 15.851 -3.902 1.00 12.79 ? 108 PHE A CG 1 ATOM 850 C CD1 . PHE A 1 108 ? 92.260 15.105 -2.736 1.00 15.96 ? 108 PHE A CD1 1 ATOM 851 C CD2 . PHE A 1 108 ? 93.493 16.377 -4.332 1.00 15.26 ? 108 PHE A CD2 1 ATOM 852 C CE1 . PHE A 1 108 ? 93.422 14.895 -2.012 1.00 18.23 ? 108 PHE A CE1 1 ATOM 853 C CE2 . PHE A 1 108 ? 94.666 16.172 -3.617 1.00 15.36 ? 108 PHE A CE2 1 ATOM 854 C CZ . PHE A 1 108 ? 94.632 15.433 -2.455 1.00 17.98 ? 108 PHE A CZ 1 ATOM 855 N N . ILE A 1 109 ? 89.318 16.583 -1.508 1.00 12.80 ? 109 ILE A N 1 ATOM 856 C CA . ILE A 1 109 ? 89.402 17.190 -0.167 1.00 12.54 ? 109 ILE A CA 1 ATOM 857 C C . ILE A 1 109 ? 90.610 16.616 0.607 1.00 13.17 ? 109 ILE A C 1 ATOM 858 O O . ILE A 1 109 ? 90.670 15.406 0.818 1.00 12.60 ? 109 ILE A O 1 ATOM 859 C CB . ILE A 1 109 ? 88.137 16.865 0.607 1.00 11.63 ? 109 ILE A CB 1 ATOM 860 C CG1 . ILE A 1 109 ? 86.945 17.061 -0.312 1.00 10.86 ? 109 ILE A CG1 1 ATOM 861 C CG2 . ILE A 1 109 ? 88.010 17.746 1.824 1.00 13.44 ? 109 ILE A CG2 1 ATOM 862 C CD1 . ILE A 1 109 ? 85.805 16.154 0.023 1.00 14.34 ? 109 ILE A CD1 1 ATOM 863 N N . ASP A 1 110 ? 91.539 17.482 1.043 1.00 11.83 ? 110 ASP A N 1 ATOM 864 C CA . ASP A 1 110 ? 92.773 17.073 1.736 1.00 10.25 ? 110 ASP A CA 1 ATOM 865 C C . ASP A 1 110 ? 93.045 17.733 3.094 1.00 13.68 ? 110 ASP A C 1 ATOM 866 O O . ASP A 1 110 ? 92.401 18.691 3.481 1.00 19.84 ? 110 ASP A O 1 ATOM 867 C CB . ASP A 1 110 ? 93.975 17.358 0.828 1.00 10.13 ? 110 ASP A CB 1 ATOM 868 C CG . ASP A 1 110 ? 95.183 16.456 1.117 1.00 18.83 ? 110 ASP A CG 1 ATOM 869 O OD1 . ASP A 1 110 ? 95.181 15.737 2.136 1.00 21.80 ? 110 ASP A OD1 1 ATOM 870 O OD2 . ASP A 1 110 ? 96.150 16.462 0.319 1.00 19.60 ? 110 ASP A OD2 1 ATOM 871 N N . LYS A 1 111 ? 94.026 17.193 3.804 1.00 16.26 ? 111 LYS A N 1 ATOM 872 C CA . LYS A 1 111 ? 94.489 17.674 5.108 1.00 17.44 ? 111 LYS A CA 1 ATOM 873 C C . LYS A 1 111 ? 93.492 18.150 6.152 1.00 18.23 ? 111 LYS A C 1 ATOM 874 O O . LYS A 1 111 ? 93.629 19.248 6.671 1.00 20.76 ? 111 LYS A O 1 ATOM 875 C CB . LYS A 1 111 ? 95.535 18.773 4.901 1.00 19.73 ? 111 LYS A CB 1 ATOM 876 C CG . LYS A 1 111 ? 96.659 18.377 3.956 1.00 22.70 ? 111 LYS A CG 1 ATOM 877 C CD . LYS A 1 111 ? 97.579 19.544 3.646 1.00 27.80 ? 111 LYS A CD 1 ATOM 878 C CE . LYS A 1 111 ? 98.508 19.240 2.467 1.00 34.51 ? 111 LYS A CE 1 ATOM 879 N NZ . LYS A 1 111 ? 97.818 19.165 1.131 1.00 37.69 ? 111 LYS A NZ 1 ATOM 880 N N . PHE A 1 112 ? 92.512 17.327 6.499 1.00 21.32 ? 112 PHE A N 1 ATOM 881 C CA . PHE A 1 112 ? 91.547 17.729 7.520 1.00 23.20 ? 112 PHE A CA 1 ATOM 882 C C . PHE A 1 112 ? 91.351 16.708 8.658 1.00 23.19 ? 112 PHE A C 1 ATOM 883 O O . PHE A 1 112 ? 92.007 15.671 8.706 1.00 25.15 ? 112 PHE A O 1 ATOM 884 C CB . PHE A 1 112 ? 90.195 18.055 6.869 1.00 22.20 ? 112 PHE A CB 1 ATOM 885 C CG . PHE A 1 112 ? 89.544 16.888 6.195 1.00 20.82 ? 112 PHE A CG 1 ATOM 886 C CD1 . PHE A 1 112 ? 90.008 16.426 4.975 1.00 21.79 ? 112 PHE A CD1 1 ATOM 887 C CD2 . PHE A 1 112 ? 88.452 16.258 6.776 1.00 22.17 ? 112 PHE A CD2 1 ATOM 888 C CE1 . PHE A 1 112 ? 89.393 15.356 4.344 1.00 22.75 ? 112 PHE A CE1 1 ATOM 889 C CE2 . PHE A 1 112 ? 87.828 15.184 6.151 1.00 20.84 ? 112 PHE A CE2 1 ATOM 890 C CZ . PHE A 1 112 ? 88.298 14.735 4.937 1.00 21.84 ? 112 PHE A CZ 1 ATOM 891 N N . THR A 1 113 ? 90.443 17.034 9.569 1.00 20.74 ? 113 THR A N 1 ATOM 892 C CA . THR A 1 113 ? 90.098 16.216 10.726 1.00 17.84 ? 113 THR A CA 1 ATOM 893 C C . THR A 1 113 ? 89.307 17.167 11.616 1.00 19.50 ? 113 THR A C 1 ATOM 894 O O . THR A 1 113 ? 89.569 18.365 11.631 1.00 20.97 ? 113 THR A O 1 ATOM 895 C CB . THR A 1 113 ? 91.352 15.731 11.492 1.00 17.03 ? 113 THR A CB 1 ATOM 896 O OG1 . THR A 1 113 ? 90.951 14.901 12.585 1.00 17.55 ? 113 THR A OG1 1 ATOM 897 C CG2 . THR A 1 113 ? 92.137 16.891 12.039 1.00 11.35 ? 113 THR A CG2 1 ATOM 898 N N . PRO A 1 114 ? 88.324 16.661 12.365 1.00 19.25 ? 114 PRO A N 1 ATOM 899 C CA . PRO A 1 114 ? 87.876 15.276 12.471 1.00 19.66 ? 114 PRO A CA 1 ATOM 900 C C . PRO A 1 114 ? 87.362 14.775 11.140 1.00 20.13 ? 114 PRO A C 1 ATOM 901 O O . PRO A 1 114 ? 86.907 15.557 10.314 1.00 16.49 ? 114 PRO A O 1 ATOM 902 C CB . PRO A 1 114 ? 86.771 15.363 13.513 1.00 21.07 ? 114 PRO A CB 1 ATOM 903 C CG . PRO A 1 114 ? 86.144 16.683 13.177 1.00 19.21 ? 114 PRO A CG 1 ATOM 904 C CD . PRO A 1 114 ? 87.352 17.569 13.001 1.00 18.10 ? 114 PRO A CD 1 ATOM 905 N N . PRO A 1 115 ? 87.422 13.453 10.923 1.00 22.86 ? 115 PRO A N 1 ATOM 906 C CA . PRO A 1 115 ? 86.958 12.837 9.677 1.00 22.68 ? 115 PRO A CA 1 ATOM 907 C C . PRO A 1 115 ? 85.458 12.958 9.473 1.00 21.51 ? 115 PRO A C 1 ATOM 908 O O . PRO A 1 115 ? 84.742 11.971 9.520 1.00 23.46 ? 115 PRO A O 1 ATOM 909 C CB . PRO A 1 115 ? 87.418 11.386 9.818 1.00 19.79 ? 115 PRO A CB 1 ATOM 910 C CG . PRO A 1 115 ? 87.381 11.164 11.286 1.00 19.94 ? 115 PRO A CG 1 ATOM 911 C CD . PRO A 1 115 ? 87.981 12.435 11.830 1.00 21.60 ? 115 PRO A CD 1 ATOM 912 N N . VAL A 1 116 ? 84.984 14.174 9.253 1.00 22.19 ? 116 VAL A N 1 ATOM 913 C CA . VAL A 1 116 ? 83.563 14.401 9.037 1.00 25.58 ? 116 VAL A CA 1 ATOM 914 C C . VAL A 1 116 ? 83.397 15.603 8.119 1.00 28.53 ? 116 VAL A C 1 ATOM 915 O O . VAL A 1 116 ? 83.874 16.707 8.423 1.00 30.60 ? 116 VAL A O 1 ATOM 916 C CB . VAL A 1 116 ? 82.837 14.694 10.347 1.00 26.25 ? 116 VAL A CB 1 ATOM 917 C CG1 . VAL A 1 116 ? 81.355 14.488 10.166 1.00 22.10 ? 116 VAL A CG1 1 ATOM 918 C CG2 . VAL A 1 116 ? 83.382 13.815 11.447 1.00 29.43 ? 116 VAL A CG2 1 ATOM 919 N N . VAL A 1 117 ? 82.700 15.394 7.007 1.00 26.54 ? 117 VAL A N 1 ATOM 920 C CA . VAL A 1 117 ? 82.513 16.455 6.044 1.00 22.02 ? 117 VAL A CA 1 ATOM 921 C C . VAL A 1 117 ? 81.418 16.109 5.038 1.00 24.26 ? 117 VAL A C 1 ATOM 922 O O . VAL A 1 117 ? 81.370 14.979 4.560 1.00 23.39 ? 117 VAL A O 1 ATOM 923 C CB . VAL A 1 117 ? 83.835 16.696 5.312 1.00 19.89 ? 117 VAL A CB 1 ATOM 924 C CG1 . VAL A 1 117 ? 84.286 15.427 4.615 1.00 17.56 ? 117 VAL A CG1 1 ATOM 925 C CG2 . VAL A 1 117 ? 83.675 17.799 4.328 1.00 29.28 ? 117 VAL A CG2 1 ATOM 926 N N . ASN A 1 118 ? 80.537 17.080 4.750 1.00 27.40 ? 118 ASN A N 1 ATOM 927 C CA . ASN A 1 118 ? 79.435 16.941 3.778 1.00 29.91 ? 118 ASN A CA 1 ATOM 928 C C . ASN A 1 118 ? 79.908 17.516 2.461 1.00 30.08 ? 118 ASN A C 1 ATOM 929 O O . ASN A 1 118 ? 80.423 18.631 2.432 1.00 32.86 ? 118 ASN A O 1 ATOM 930 C CB . ASN A 1 118 ? 78.208 17.740 4.185 1.00 35.77 ? 118 ASN A CB 1 ATOM 931 C CG . ASN A 1 118 ? 77.503 17.155 5.359 1.00 49.11 ? 118 ASN A CG 1 ATOM 932 O OD1 . ASN A 1 118 ? 77.373 15.941 5.458 1.00 53.46 ? 118 ASN A OD1 1 ATOM 933 N ND2 . ASN A 1 118 ? 77.022 18.022 6.244 1.00 62.01 ? 118 ASN A ND2 1 ATOM 934 N N . VAL A 1 119 ? 79.712 16.780 1.370 1.00 27.53 ? 119 VAL A N 1 ATOM 935 C CA . VAL A 1 119 ? 80.169 17.249 0.066 1.00 22.22 ? 119 VAL A CA 1 ATOM 936 C C . VAL A 1 119 ? 79.057 17.207 -0.983 1.00 25.45 ? 119 VAL A C 1 ATOM 937 O O . VAL A 1 119 ? 78.414 16.175 -1.176 1.00 25.88 ? 119 VAL A O 1 ATOM 938 C CB . VAL A 1 119 ? 81.386 16.408 -0.412 1.00 10.59 ? 119 VAL A CB 1 ATOM 939 C CG1 . VAL A 1 119 ? 81.873 16.902 -1.735 1.00 6.12 ? 119 VAL A CG1 1 ATOM 940 C CG2 . VAL A 1 119 ? 82.505 16.505 0.592 1.00 3.29 ? 119 VAL A CG2 1 ATOM 941 N N . THR A 1 120 ? 78.826 18.331 -1.658 1.00 25.30 ? 120 THR A N 1 ATOM 942 C CA . THR A 1 120 ? 77.782 18.382 -2.678 1.00 25.83 ? 120 THR A CA 1 ATOM 943 C C . THR A 1 120 ? 78.248 18.877 -4.035 1.00 27.59 ? 120 THR A C 1 ATOM 944 O O . THR A 1 120 ? 79.024 19.830 -4.127 1.00 29.03 ? 120 THR A O 1 ATOM 945 C CB . THR A 1 120 ? 76.656 19.290 -2.255 1.00 23.84 ? 120 THR A CB 1 ATOM 946 O OG1 . THR A 1 120 ? 76.211 18.899 -0.957 1.00 26.24 ? 120 THR A OG1 1 ATOM 947 C CG2 . THR A 1 120 ? 75.510 19.206 -3.253 1.00 19.23 ? 120 THR A CG2 1 ATOM 948 N N . TRP A 1 121 ? 77.775 18.223 -5.092 1.00 26.46 ? 121 TRP A N 1 ATOM 949 C CA . TRP A 1 121 ? 78.132 18.649 -6.432 1.00 24.21 ? 121 TRP A CA 1 ATOM 950 C C . TRP A 1 121 ? 76.984 19.548 -6.886 1.00 26.83 ? 121 TRP A C 1 ATOM 951 O O . TRP A 1 121 ? 75.811 19.285 -6.597 1.00 24.88 ? 121 TRP A O 1 ATOM 952 C CB . TRP A 1 121 ? 78.271 17.464 -7.400 1.00 20.26 ? 121 TRP A CB 1 ATOM 953 C CG . TRP A 1 121 ? 79.562 16.700 -7.347 1.00 16.48 ? 121 TRP A CG 1 ATOM 954 C CD1 . TRP A 1 121 ? 79.722 15.406 -6.947 1.00 20.01 ? 121 TRP A CD1 1 ATOM 955 C CD2 . TRP A 1 121 ? 80.866 17.166 -7.724 1.00 17.62 ? 121 TRP A CD2 1 ATOM 956 N NE1 . TRP A 1 121 ? 81.041 15.036 -7.046 1.00 20.76 ? 121 TRP A NE1 1 ATOM 957 C CE2 . TRP A 1 121 ? 81.766 16.098 -7.520 1.00 18.25 ? 121 TRP A CE2 1 ATOM 958 C CE3 . TRP A 1 121 ? 81.364 18.381 -8.213 1.00 23.07 ? 121 TRP A CE3 1 ATOM 959 C CZ2 . TRP A 1 121 ? 83.143 16.209 -7.789 1.00 16.02 ? 121 TRP A CZ2 1 ATOM 960 C CZ3 . TRP A 1 121 ? 82.743 18.489 -8.482 1.00 22.28 ? 121 TRP A CZ3 1 ATOM 961 C CH2 . TRP A 1 121 ? 83.609 17.406 -8.266 1.00 17.04 ? 121 TRP A CH2 1 ATOM 962 N N . LEU A 1 122 ? 77.336 20.613 -7.595 1.00 26.96 ? 122 LEU A N 1 ATOM 963 C CA . LEU A 1 122 ? 76.364 21.558 -8.093 1.00 25.97 ? 122 LEU A CA 1 ATOM 964 C C . LEU A 1 122 ? 76.650 21.904 -9.546 1.00 30.43 ? 122 LEU A C 1 ATOM 965 O O . LEU A 1 122 ? 77.708 22.457 -9.867 1.00 29.52 ? 122 LEU A O 1 ATOM 966 C CB . LEU A 1 122 ? 76.438 22.840 -7.274 1.00 23.82 ? 122 LEU A CB 1 ATOM 967 C CG . LEU A 1 122 ? 76.234 22.748 -5.776 1.00 18.38 ? 122 LEU A CG 1 ATOM 968 C CD1 . LEU A 1 122 ? 76.785 23.975 -5.107 1.00 15.21 ? 122 LEU A CD1 1 ATOM 969 C CD2 . LEU A 1 122 ? 74.771 22.588 -5.501 1.00 17.95 ? 122 LEU A CD2 1 ATOM 970 N N . ARG A 1 123 ? 75.722 21.570 -10.433 1.00 35.45 ? 123 ARG A N 1 ATOM 971 C CA . ARG A 1 123 ? 75.893 21.931 -11.831 1.00 40.80 ? 123 ARG A CA 1 ATOM 972 C C . ARG A 1 123 ? 75.039 23.167 -12.006 1.00 41.89 ? 123 ARG A C 1 ATOM 973 O O . ARG A 1 123 ? 73.806 23.087 -12.065 1.00 41.41 ? 123 ARG A O 1 ATOM 974 C CB . ARG A 1 123 ? 75.388 20.857 -12.786 1.00 46.21 ? 123 ARG A CB 1 ATOM 975 C CG . ARG A 1 123 ? 75.807 21.167 -14.213 1.00 54.25 ? 123 ARG A CG 1 ATOM 976 C CD . ARG A 1 123 ? 74.952 20.486 -15.252 1.00 60.49 ? 123 ARG A CD 1 ATOM 977 N NE . ARG A 1 123 ? 74.792 19.067 -14.988 1.00 65.93 ? 123 ARG A NE 1 ATOM 978 C CZ . ARG A 1 123 ? 74.350 18.201 -15.888 1.00 71.43 ? 123 ARG A CZ 1 ATOM 979 N NH1 . ARG A 1 123 ? 74.033 18.626 -17.108 1.00 70.80 ? 123 ARG A NH1 1 ATOM 980 N NH2 . ARG A 1 123 ? 74.217 16.920 -15.564 1.00 75.36 ? 123 ARG A NH2 1 ATOM 981 N N . ASN A 1 124 ? 75.694 24.315 -12.083 1.00 42.83 ? 124 ASN A N 1 ATOM 982 C CA . ASN A 1 124 ? 74.972 25.560 -12.222 1.00 42.57 ? 124 ASN A CA 1 ATOM 983 C C . ASN A 1 124 ? 74.093 25.639 -10.993 1.00 41.83 ? 124 ASN A C 1 ATOM 984 O O . ASN A 1 124 ? 72.887 25.386 -11.044 1.00 38.61 ? 124 ASN A O 1 ATOM 985 C CB . ASN A 1 124 ? 74.120 25.553 -13.491 1.00 39.70 ? 124 ASN A CB 1 ATOM 986 C CG . ASN A 1 124 ? 74.868 24.997 -14.681 1.00 38.49 ? 124 ASN A CG 1 ATOM 987 O OD1 . ASN A 1 124 ? 75.962 25.456 -15.029 1.00 35.90 ? 124 ASN A OD1 1 ATOM 988 N ND2 . ASN A 1 124 ? 74.283 23.996 -15.312 1.00 39.96 ? 124 ASN A ND2 1 ATOM 989 N N . GLY A 1 125 ? 74.742 25.941 -9.876 1.00 42.31 ? 125 GLY A N 1 ATOM 990 C CA . GLY A 1 125 ? 74.054 26.089 -8.609 1.00 45.91 ? 125 GLY A CA 1 ATOM 991 C C . GLY A 1 125 ? 72.971 25.114 -8.170 1.00 44.92 ? 125 GLY A C 1 ATOM 992 O O . GLY A 1 125 ? 72.258 25.396 -7.210 1.00 47.93 ? 125 GLY A O 1 ATOM 993 N N . LYS A 1 126 ? 72.807 23.988 -8.845 1.00 43.05 ? 126 LYS A N 1 ATOM 994 C CA . LYS A 1 126 ? 71.802 23.045 -8.385 1.00 43.82 ? 126 LYS A CA 1 ATOM 995 C C . LYS A 1 126 ? 72.463 21.718 -8.005 1.00 43.64 ? 126 LYS A C 1 ATOM 996 O O . LYS A 1 126 ? 73.430 21.283 -8.635 1.00 45.67 ? 126 LYS A O 1 ATOM 997 C CB . LYS A 1 126 ? 70.732 22.874 -9.445 1.00 48.49 ? 126 LYS A CB 1 ATOM 998 C CG . LYS A 1 126 ? 69.987 24.174 -9.694 1.00 55.56 ? 126 LYS A CG 1 ATOM 999 C CD . LYS A 1 126 ? 68.833 23.999 -10.669 1.00 62.80 ? 126 LYS A CD 1 ATOM 1000 C CE . LYS A 1 126 ? 68.043 25.293 -10.833 1.00 64.46 ? 126 LYS A CE 1 ATOM 1001 N NZ . LYS A 1 126 ? 66.922 25.124 -11.798 1.00 66.17 ? 126 LYS A NZ 1 ATOM 1002 N N . PRO A 1 127 ? 71.973 21.068 -6.943 1.00 40.60 ? 127 PRO A N 1 ATOM 1003 C CA . PRO A 1 127 ? 72.591 19.804 -6.548 1.00 39.57 ? 127 PRO A CA 1 ATOM 1004 C C . PRO A 1 127 ? 72.343 18.650 -7.502 1.00 39.93 ? 127 PRO A C 1 ATOM 1005 O O . PRO A 1 127 ? 71.266 18.533 -8.084 1.00 39.81 ? 127 PRO A O 1 ATOM 1006 C CB . PRO A 1 127 ? 71.993 19.546 -5.170 1.00 35.56 ? 127 PRO A CB 1 ATOM 1007 C CG . PRO A 1 127 ? 71.689 20.900 -4.677 1.00 34.99 ? 127 PRO A CG 1 ATOM 1008 C CD . PRO A 1 127 ? 71.073 21.541 -5.885 1.00 38.19 ? 127 PRO A CD 1 ATOM 1009 N N . VAL A 1 128 ? 73.362 17.807 -7.645 1.00 39.65 ? 128 VAL A N 1 ATOM 1010 C CA . VAL A 1 128 ? 73.308 16.626 -8.495 1.00 39.97 ? 128 VAL A CA 1 ATOM 1011 C C . VAL A 1 128 ? 73.518 15.396 -7.615 1.00 42.03 ? 128 VAL A C 1 ATOM 1012 O O . VAL A 1 128 ? 74.427 15.363 -6.781 1.00 39.18 ? 128 VAL A O 1 ATOM 1013 C CB . VAL A 1 128 ? 74.389 16.687 -9.590 1.00 39.83 ? 128 VAL A CB 1 ATOM 1014 C CG1 . VAL A 1 128 ? 75.502 17.612 -9.153 1.00 40.97 ? 128 VAL A CG1 1 ATOM 1015 C CG2 . VAL A 1 128 ? 74.939 15.294 -9.877 1.00 39.01 ? 128 VAL A CG2 1 ATOM 1016 N N . THR A 1 129 ? 72.658 14.396 -7.805 1.00 46.37 ? 129 THR A N 1 ATOM 1017 C CA . THR A 1 129 ? 72.696 13.155 -7.030 1.00 47.17 ? 129 THR A CA 1 ATOM 1018 C C . THR A 1 129 ? 72.639 11.951 -7.951 1.00 49.65 ? 129 THR A C 1 ATOM 1019 O O . THR A 1 129 ? 71.728 11.129 -7.851 1.00 49.61 ? 129 THR A O 1 ATOM 1020 C CB . THR A 1 129 ? 71.477 13.031 -6.096 1.00 44.73 ? 129 THR A CB 1 ATOM 1021 O OG1 . THR A 1 129 ? 70.793 14.288 -6.020 1.00 44.10 ? 129 THR A OG1 1 ATOM 1022 C CG2 . THR A 1 129 ? 71.913 12.578 -4.713 1.00 41.93 ? 129 THR A CG2 1 ATOM 1023 N N . THR A 1 130 ? 73.600 11.830 -8.848 1.00 50.91 ? 130 THR A N 1 ATOM 1024 C CA . THR A 1 130 ? 73.568 10.701 -9.751 1.00 56.15 ? 130 THR A CA 1 ATOM 1025 C C . THR A 1 130 ? 74.945 10.380 -10.308 1.00 56.09 ? 130 THR A C 1 ATOM 1026 O O . THR A 1 130 ? 75.728 11.278 -10.612 1.00 60.39 ? 130 THR A O 1 ATOM 1027 C CB . THR A 1 130 ? 72.577 10.964 -10.930 1.00 59.26 ? 130 THR A CB 1 ATOM 1028 O OG1 . THR A 1 130 ? 72.846 12.246 -11.508 1.00 62.24 ? 130 THR A OG1 1 ATOM 1029 C CG2 . THR A 1 130 ? 71.122 10.926 -10.453 1.00 57.80 ? 130 THR A CG2 1 ATOM 1030 N N . GLY A 1 131 ? 75.240 9.093 -10.432 1.00 54.50 ? 131 GLY A N 1 ATOM 1031 C CA . GLY A 1 131 ? 76.520 8.683 -10.975 1.00 51.56 ? 131 GLY A CA 1 ATOM 1032 C C . GLY A 1 131 ? 77.659 9.159 -10.110 1.00 48.89 ? 131 GLY A C 1 ATOM 1033 O O . GLY A 1 131 ? 78.808 8.779 -10.324 1.00 52.93 ? 131 GLY A O 1 ATOM 1034 N N . VAL A 1 132 ? 77.336 9.987 -9.123 1.00 43.29 ? 132 VAL A N 1 ATOM 1035 C CA . VAL A 1 132 ? 78.336 10.523 -8.221 1.00 38.36 ? 132 VAL A CA 1 ATOM 1036 C C . VAL A 1 132 ? 78.830 9.418 -7.297 1.00 36.19 ? 132 VAL A C 1 ATOM 1037 O O . VAL A 1 132 ? 78.093 8.495 -6.977 1.00 36.19 ? 132 VAL A O 1 ATOM 1038 C CB . VAL A 1 132 ? 77.749 11.686 -7.412 1.00 36.29 ? 132 VAL A CB 1 ATOM 1039 C CG1 . VAL A 1 132 ? 76.436 11.264 -6.808 1.00 32.63 ? 132 VAL A CG1 1 ATOM 1040 C CG2 . VAL A 1 132 ? 78.729 12.135 -6.343 1.00 40.20 ? 132 VAL A CG2 1 ATOM 1041 N N . SER A 1 133 ? 80.087 9.509 -6.880 1.00 36.03 ? 133 SER A N 1 ATOM 1042 C CA . SER A 1 133 ? 80.682 8.502 -6.014 1.00 36.36 ? 133 SER A CA 1 ATOM 1043 C C . SER A 1 133 ? 81.823 9.070 -5.176 1.00 36.17 ? 133 SER A C 1 ATOM 1044 O O . SER A 1 133 ? 82.569 9.939 -5.626 1.00 37.09 ? 133 SER A O 1 ATOM 1045 C CB . SER A 1 133 ? 81.208 7.353 -6.864 1.00 36.97 ? 133 SER A CB 1 ATOM 1046 O OG . SER A 1 133 ? 82.120 7.831 -7.836 1.00 38.18 ? 133 SER A OG 1 ATOM 1047 N N . GLU A 1 134 ? 81.969 8.554 -3.962 1.00 34.10 ? 134 GLU A N 1 ATOM 1048 C CA . GLU A 1 134 ? 83.005 9.020 -3.056 1.00 30.95 ? 134 GLU A CA 1 ATOM 1049 C C . GLU A 1 134 ? 83.825 7.847 -2.549 1.00 29.22 ? 134 GLU A C 1 ATOM 1050 O O . GLU A 1 134 ? 83.504 6.693 -2.816 1.00 31.89 ? 134 GLU A O 1 ATOM 1051 C CB . GLU A 1 134 ? 82.348 9.731 -1.876 1.00 32.85 ? 134 GLU A CB 1 ATOM 1052 C CG . GLU A 1 134 ? 81.448 8.814 -1.056 1.00 35.88 ? 134 GLU A CG 1 ATOM 1053 C CD . GLU A 1 134 ? 80.409 9.558 -0.227 1.00 39.86 ? 134 GLU A CD 1 ATOM 1054 O OE1 . GLU A 1 134 ? 79.394 10.001 -0.810 1.00 44.78 ? 134 GLU A OE1 1 ATOM 1055 O OE2 . GLU A 1 134 ? 80.606 9.700 1.004 1.00 37.95 ? 134 GLU A OE2 1 ATOM 1056 N N . THR A 1 135 ? 84.885 8.149 -1.814 1.00 25.52 ? 135 THR A N 1 ATOM 1057 C CA . THR A 1 135 ? 85.740 7.124 -1.236 1.00 24.69 ? 135 THR A CA 1 ATOM 1058 C C . THR A 1 135 ? 85.627 7.304 0.270 1.00 27.35 ? 135 THR A C 1 ATOM 1059 O O . THR A 1 135 ? 85.149 8.337 0.724 1.00 31.14 ? 135 THR A O 1 ATOM 1060 C CB . THR A 1 135 ? 87.207 7.340 -1.614 1.00 24.60 ? 135 THR A CB 1 ATOM 1061 O OG1 . THR A 1 135 ? 87.719 8.479 -0.911 1.00 20.63 ? 135 THR A OG1 1 ATOM 1062 C CG2 . THR A 1 135 ? 87.339 7.575 -3.095 1.00 20.74 ? 135 THR A CG2 1 ATOM 1063 N N . VAL A 1 136 ? 86.065 6.321 1.049 1.00 27.88 ? 136 VAL A N 1 ATOM 1064 C CA . VAL A 1 136 ? 86.004 6.441 2.510 1.00 24.85 ? 136 VAL A CA 1 ATOM 1065 C C . VAL A 1 136 ? 87.073 7.454 2.929 1.00 25.31 ? 136 VAL A C 1 ATOM 1066 O O . VAL A 1 136 ? 87.707 8.090 2.076 1.00 23.01 ? 136 VAL A O 1 ATOM 1067 C CB . VAL A 1 136 ? 86.297 5.080 3.209 1.00 21.97 ? 136 VAL A CB 1 ATOM 1068 C CG1 . VAL A 1 136 ? 85.720 3.950 2.384 1.00 19.84 ? 136 VAL A CG1 1 ATOM 1069 C CG2 . VAL A 1 136 ? 87.809 4.873 3.404 1.00 20.29 ? 136 VAL A CG2 1 ATOM 1070 N N . PHE A 1 137 ? 87.274 7.611 4.232 1.00 21.89 ? 137 PHE A N 1 ATOM 1071 C CA . PHE A 1 137 ? 88.295 8.527 4.701 1.00 19.94 ? 137 PHE A CA 1 ATOM 1072 C C . PHE A 1 137 ? 89.678 7.840 4.690 1.00 20.62 ? 137 PHE A C 1 ATOM 1073 O O . PHE A 1 137 ? 89.947 6.917 5.463 1.00 20.53 ? 137 PHE A O 1 ATOM 1074 C CB . PHE A 1 137 ? 87.949 9.025 6.100 1.00 18.55 ? 137 PHE A CB 1 ATOM 1075 C CG . PHE A 1 137 ? 86.725 9.881 6.149 1.00 23.26 ? 137 PHE A CG 1 ATOM 1076 C CD1 . PHE A 1 137 ? 85.460 9.318 6.092 1.00 25.83 ? 137 PHE A CD1 1 ATOM 1077 C CD2 . PHE A 1 137 ? 86.832 11.264 6.257 1.00 30.71 ? 137 PHE A CD2 1 ATOM 1078 C CE1 . PHE A 1 137 ? 84.306 10.125 6.146 1.00 24.44 ? 137 PHE A CE1 1 ATOM 1079 C CE2 . PHE A 1 137 ? 85.686 12.080 6.310 1.00 29.15 ? 137 PHE A CE2 1 ATOM 1080 C CZ . PHE A 1 137 ? 84.425 11.502 6.255 1.00 26.36 ? 137 PHE A CZ 1 ATOM 1081 N N . LEU A 1 138 ? 90.551 8.298 3.799 1.00 17.75 ? 138 LEU A N 1 ATOM 1082 C CA . LEU A 1 138 ? 91.889 7.743 3.681 1.00 13.15 ? 138 LEU A CA 1 ATOM 1083 C C . LEU A 1 138 ? 92.877 8.411 4.616 1.00 13.20 ? 138 LEU A C 1 ATOM 1084 O O . LEU A 1 138 ? 92.906 9.625 4.732 1.00 15.27 ? 138 LEU A O 1 ATOM 1085 C CB . LEU A 1 138 ? 92.395 7.892 2.254 1.00 9.34 ? 138 LEU A CB 1 ATOM 1086 C CG . LEU A 1 138 ? 91.718 7.007 1.217 1.00 9.62 ? 138 LEU A CG 1 ATOM 1087 C CD1 . LEU A 1 138 ? 90.294 7.476 0.934 1.00 7.80 ? 138 LEU A CD1 1 ATOM 1088 C CD2 . LEU A 1 138 ? 92.549 7.046 -0.036 1.00 8.10 ? 138 LEU A CD2 1 ATOM 1089 N N . PRO A 1 139 ? 93.718 7.618 5.284 1.00 13.17 ? 139 PRO A N 1 ATOM 1090 C CA . PRO A 1 139 ? 94.743 8.058 6.227 1.00 14.73 ? 139 PRO A CA 1 ATOM 1091 C C . PRO A 1 139 ? 95.909 8.782 5.606 1.00 18.31 ? 139 PRO A C 1 ATOM 1092 O O . PRO A 1 139 ? 96.296 8.494 4.481 1.00 20.17 ? 139 PRO A O 1 ATOM 1093 C CB . PRO A 1 139 ? 95.209 6.760 6.847 1.00 13.35 ? 139 PRO A CB 1 ATOM 1094 C CG . PRO A 1 139 ? 95.075 5.823 5.715 1.00 15.91 ? 139 PRO A CG 1 ATOM 1095 C CD . PRO A 1 139 ? 93.702 6.153 5.213 1.00 13.72 ? 139 PRO A CD 1 ATOM 1096 N N . ARG A 1 140 ? 96.474 9.707 6.378 1.00 25.62 ? 140 ARG A N 1 ATOM 1097 C CA . ARG A 1 140 ? 97.640 10.494 5.986 1.00 29.36 ? 140 ARG A CA 1 ATOM 1098 C C . ARG A 1 140 ? 98.724 10.234 7.040 1.00 33.30 ? 140 ARG A C 1 ATOM 1099 O O . ARG A 1 140 ? 98.429 9.782 8.151 1.00 33.60 ? 140 ARG A O 1 ATOM 1100 C CB . ARG A 1 140 ? 97.311 11.988 5.981 1.00 30.07 ? 140 ARG A CB 1 ATOM 1101 C CG . ARG A 1 140 ? 96.276 12.448 4.968 1.00 30.49 ? 140 ARG A CG 1 ATOM 1102 C CD . ARG A 1 140 ? 96.042 13.946 5.113 1.00 28.38 ? 140 ARG A CD 1 ATOM 1103 N NE . ARG A 1 140 ? 97.300 14.689 5.080 1.00 25.79 ? 140 ARG A NE 1 ATOM 1104 C CZ . ARG A 1 140 ? 97.963 15.001 3.971 1.00 30.38 ? 140 ARG A CZ 1 ATOM 1105 N NH1 . ARG A 1 140 ? 97.494 14.647 2.775 1.00 28.41 ? 140 ARG A NH1 1 ATOM 1106 N NH2 . ARG A 1 140 ? 99.114 15.657 4.059 1.00 34.17 ? 140 ARG A NH2 1 ATOM 1107 N N . GLU A 1 141 ? 99.975 10.527 6.700 1.00 36.52 ? 141 GLU A N 1 ATOM 1108 C CA . GLU A 1 141 ? 101.066 10.317 7.639 1.00 39.92 ? 141 GLU A CA 1 ATOM 1109 C C . GLU A 1 141 ? 101.013 11.265 8.821 1.00 37.34 ? 141 GLU A C 1 ATOM 1110 O O . GLU A 1 141 ? 101.687 11.045 9.820 1.00 38.88 ? 141 GLU A O 1 ATOM 1111 C CB . GLU A 1 141 ? 102.411 10.473 6.943 1.00 49.38 ? 141 GLU A CB 1 ATOM 1112 C CG . GLU A 1 141 ? 102.683 9.436 5.873 1.00 66.03 ? 141 GLU A CG 1 ATOM 1113 C CD . GLU A 1 141 ? 104.150 9.035 5.828 1.00 77.25 ? 141 GLU A CD 1 ATOM 1114 O OE1 . GLU A 1 141 ? 105.013 9.945 5.768 1.00 82.19 ? 141 GLU A OE1 1 ATOM 1115 O OE2 . GLU A 1 141 ? 104.437 7.812 5.855 1.00 82.26 ? 141 GLU A OE2 1 ATOM 1116 N N . ASP A 1 142 ? 100.222 12.325 8.702 1.00 37.22 ? 142 ASP A N 1 ATOM 1117 C CA . ASP A 1 142 ? 100.088 13.306 9.774 1.00 35.79 ? 142 ASP A CA 1 ATOM 1118 C C . ASP A 1 142 ? 98.809 13.064 10.555 1.00 34.61 ? 142 ASP A C 1 ATOM 1119 O O . ASP A 1 142 ? 98.361 13.911 11.315 1.00 33.73 ? 142 ASP A O 1 ATOM 1120 C CB . ASP A 1 142 ? 100.100 14.735 9.219 1.00 33.57 ? 142 ASP A CB 1 ATOM 1121 C CG . ASP A 1 142 ? 99.094 14.936 8.116 1.00 36.30 ? 142 ASP A CG 1 ATOM 1122 O OD1 . ASP A 1 142 ? 97.949 14.470 8.283 1.00 38.54 ? 142 ASP A OD1 1 ATOM 1123 O OD2 . ASP A 1 142 ? 99.443 15.560 7.089 1.00 37.19 ? 142 ASP A OD2 1 ATOM 1124 N N . HIS A 1 143 ? 98.214 11.902 10.342 1.00 35.77 ? 143 HIS A N 1 ATOM 1125 C CA . HIS A 1 143 ? 97.010 11.530 11.059 1.00 36.38 ? 143 HIS A CA 1 ATOM 1126 C C . HIS A 1 143 ? 95.798 12.405 10.774 1.00 33.95 ? 143 HIS A C 1 ATOM 1127 O O . HIS A 1 143 ? 94.901 12.573 11.615 1.00 33.08 ? 143 HIS A O 1 ATOM 1128 C CB . HIS A 1 143 ? 97.341 11.490 12.542 1.00 37.22 ? 143 HIS A CB 1 ATOM 1129 C CG . HIS A 1 143 ? 98.621 10.777 12.825 1.00 38.58 ? 143 HIS A CG 1 ATOM 1130 N ND1 . HIS A 1 143 ? 98.869 9.499 12.375 1.00 40.81 ? 143 HIS A ND1 1 ATOM 1131 C CD2 . HIS A 1 143 ? 99.741 11.173 13.471 1.00 42.28 ? 143 HIS A CD2 1 ATOM 1132 C CE1 . HIS A 1 143 ? 100.087 9.137 12.734 1.00 42.75 ? 143 HIS A CE1 1 ATOM 1133 N NE2 . HIS A 1 143 ? 100.638 10.135 13.401 1.00 44.29 ? 143 HIS A NE2 1 ATOM 1134 N N . LEU A 1 144 ? 95.795 12.980 9.579 1.00 30.82 ? 144 LEU A N 1 ATOM 1135 C CA . LEU A 1 144 ? 94.667 13.769 9.127 1.00 27.73 ? 144 LEU A CA 1 ATOM 1136 C C . LEU A 1 144 ? 93.971 12.858 8.128 1.00 26.89 ? 144 LEU A C 1 ATOM 1137 O O . LEU A 1 144 ? 94.189 11.636 8.125 1.00 27.64 ? 144 LEU A O 1 ATOM 1138 C CB . LEU A 1 144 ? 95.106 15.057 8.441 1.00 25.22 ? 144 LEU A CB 1 ATOM 1139 C CG . LEU A 1 144 ? 95.782 16.104 9.325 1.00 24.63 ? 144 LEU A CG 1 ATOM 1140 C CD1 . LEU A 1 144 ? 95.884 17.403 8.546 1.00 23.76 ? 144 LEU A CD1 1 ATOM 1141 C CD2 . LEU A 1 144 ? 94.994 16.312 10.601 1.00 23.02 ? 144 LEU A CD2 1 ATOM 1142 N N . PHE A 1 145 ? 93.136 13.427 7.277 1.00 22.67 ? 145 PHE A N 1 ATOM 1143 C CA . PHE A 1 145 ? 92.446 12.588 6.332 1.00 23.35 ? 145 PHE A CA 1 ATOM 1144 C C . PHE A 1 145 ? 92.450 13.160 4.949 1.00 23.44 ? 145 PHE A C 1 ATOM 1145 O O . PHE A 1 145 ? 92.803 14.306 4.733 1.00 27.49 ? 145 PHE A O 1 ATOM 1146 C CB . PHE A 1 145 ? 91.006 12.340 6.784 1.00 24.16 ? 145 PHE A CB 1 ATOM 1147 C CG . PHE A 1 145 ? 90.904 11.611 8.095 1.00 25.31 ? 145 PHE A CG 1 ATOM 1148 C CD1 . PHE A 1 145 ? 91.059 12.282 9.294 1.00 26.75 ? 145 PHE A CD1 1 ATOM 1149 C CD2 . PHE A 1 145 ? 90.704 10.244 8.130 1.00 27.95 ? 145 PHE A CD2 1 ATOM 1150 C CE1 . PHE A 1 145 ? 91.019 11.598 10.504 1.00 26.73 ? 145 PHE A CE1 1 ATOM 1151 C CE2 . PHE A 1 145 ? 90.666 9.558 9.340 1.00 27.96 ? 145 PHE A CE2 1 ATOM 1152 C CZ . PHE A 1 145 ? 90.824 10.237 10.522 1.00 24.59 ? 145 PHE A CZ 1 ATOM 1153 N N . ARG A 1 146 ? 92.061 12.328 4.007 1.00 22.29 ? 146 ARG A N 1 ATOM 1154 C CA . ARG A 1 146 ? 91.996 12.721 2.630 1.00 20.56 ? 146 ARG A CA 1 ATOM 1155 C C . ARG A 1 146 ? 90.748 12.032 2.133 1.00 18.73 ? 146 ARG A C 1 ATOM 1156 O O . ARG A 1 146 ? 90.391 10.969 2.629 1.00 21.24 ? 146 ARG A O 1 ATOM 1157 C CB . ARG A 1 146 ? 93.220 12.218 1.896 1.00 24.83 ? 146 ARG A CB 1 ATOM 1158 C CG . ARG A 1 146 ? 93.347 12.806 0.524 1.00 39.90 ? 146 ARG A CG 1 ATOM 1159 C CD . ARG A 1 146 ? 94.768 13.277 0.277 1.00 51.71 ? 146 ARG A CD 1 ATOM 1160 N NE . ARG A 1 146 ? 95.576 12.292 -0.432 1.00 59.62 ? 146 ARG A NE 1 ATOM 1161 C CZ . ARG A 1 146 ? 96.849 12.482 -0.750 1.00 63.81 ? 146 ARG A CZ 1 ATOM 1162 N NH1 . ARG A 1 146 ? 97.452 13.620 -0.416 1.00 62.43 ? 146 ARG A NH1 1 ATOM 1163 N NH2 . ARG A 1 146 ? 97.515 11.540 -1.403 1.00 69.33 ? 146 ARG A NH2 1 ATOM 1164 N N . LYS A 1 147 ? 90.059 12.636 1.180 1.00 14.73 ? 147 LYS A N 1 ATOM 1165 C CA . LYS A 1 147 ? 88.850 12.021 0.673 1.00 11.13 ? 147 LYS A CA 1 ATOM 1166 C C . LYS A 1 147 ? 88.679 12.397 -0.790 1.00 12.41 ? 147 LYS A C 1 ATOM 1167 O O . LYS A 1 147 ? 89.277 13.362 -1.273 1.00 13.55 ? 147 LYS A O 1 ATOM 1168 C CB . LYS A 1 147 ? 87.660 12.474 1.507 1.00 6.50 ? 147 LYS A CB 1 ATOM 1169 C CG . LYS A 1 147 ? 86.423 11.614 1.366 1.00 13.91 ? 147 LYS A CG 1 ATOM 1170 C CD . LYS A 1 147 ? 85.336 12.040 2.384 1.00 16.44 ? 147 LYS A CD 1 ATOM 1171 C CE . LYS A 1 147 ? 84.079 11.158 2.331 1.00 11.70 ? 147 LYS A CE 1 ATOM 1172 N NZ . LYS A 1 147 ? 83.470 11.103 0.975 1.00 10.46 ? 147 LYS A NZ 1 ATOM 1173 N N . PHE A 1 148 ? 87.890 11.615 -1.506 1.00 9.86 ? 148 PHE A N 1 ATOM 1174 C CA . PHE A 1 148 ? 87.676 11.883 -2.909 1.00 13.33 ? 148 PHE A CA 1 ATOM 1175 C C . PHE A 1 148 ? 86.211 11.805 -3.300 1.00 18.20 ? 148 PHE A C 1 ATOM 1176 O O . PHE A 1 148 ? 85.447 10.989 -2.778 1.00 22.43 ? 148 PHE A O 1 ATOM 1177 C CB . PHE A 1 148 ? 88.448 10.889 -3.772 1.00 11.46 ? 148 PHE A CB 1 ATOM 1178 C CG . PHE A 1 148 ? 89.918 11.141 -3.834 1.00 13.31 ? 148 PHE A CG 1 ATOM 1179 C CD1 . PHE A 1 148 ? 90.776 10.541 -2.931 1.00 13.35 ? 148 PHE A CD1 1 ATOM 1180 C CD2 . PHE A 1 148 ? 90.448 11.977 -4.809 1.00 17.06 ? 148 PHE A CD2 1 ATOM 1181 C CE1 . PHE A 1 148 ? 92.147 10.767 -2.996 1.00 15.82 ? 148 PHE A CE1 1 ATOM 1182 C CE2 . PHE A 1 148 ? 91.816 12.213 -4.884 1.00 17.67 ? 148 PHE A CE2 1 ATOM 1183 C CZ . PHE A 1 148 ? 92.666 11.605 -3.974 1.00 18.90 ? 148 PHE A CZ 1 ATOM 1184 N N . HIS A 1 149 ? 85.813 12.675 -4.213 1.00 17.81 ? 149 HIS A N 1 ATOM 1185 C CA . HIS A 1 149 ? 84.464 12.635 -4.704 1.00 20.91 ? 149 HIS A CA 1 ATOM 1186 C C . HIS A 1 149 ? 84.533 12.629 -6.199 1.00 25.90 ? 149 HIS A C 1 ATOM 1187 O O . HIS A 1 149 ? 85.405 13.276 -6.801 1.00 27.81 ? 149 HIS A O 1 ATOM 1188 C CB . HIS A 1 149 ? 83.647 13.806 -4.225 1.00 18.55 ? 149 HIS A CB 1 ATOM 1189 C CG . HIS A 1 149 ? 82.847 13.497 -3.010 1.00 21.66 ? 149 HIS A CG 1 ATOM 1190 N ND1 . HIS A 1 149 ? 83.390 13.506 -1.741 1.00 21.24 ? 149 HIS A ND1 1 ATOM 1191 C CD2 . HIS A 1 149 ? 81.554 13.129 -2.870 1.00 20.24 ? 149 HIS A CD2 1 ATOM 1192 C CE1 . HIS A 1 149 ? 82.461 13.160 -0.870 1.00 20.90 ? 149 HIS A CE1 1 ATOM 1193 N NE2 . HIS A 1 149 ? 81.339 12.926 -1.528 1.00 24.46 ? 149 HIS A NE2 1 ATOM 1194 N N . TYR A 1 150 ? 83.606 11.895 -6.799 1.00 23.50 ? 150 TYR A N 1 ATOM 1195 C CA . TYR A 1 150 ? 83.588 11.773 -8.229 1.00 17.46 ? 150 TYR A CA 1 ATOM 1196 C C . TYR A 1 150 ? 82.283 12.196 -8.853 1.00 17.06 ? 150 TYR A C 1 ATOM 1197 O O . TYR A 1 150 ? 81.213 11.931 -8.323 1.00 16.01 ? 150 TYR A O 1 ATOM 1198 C CB . TYR A 1 150 ? 83.918 10.335 -8.590 1.00 12.91 ? 150 TYR A CB 1 ATOM 1199 C CG . TYR A 1 150 ? 85.259 9.906 -8.056 1.00 14.31 ? 150 TYR A CG 1 ATOM 1200 C CD1 . TYR A 1 150 ? 86.394 10.670 -8.289 1.00 18.39 ? 150 TYR A CD1 1 ATOM 1201 C CD2 . TYR A 1 150 ? 85.403 8.731 -7.332 1.00 18.91 ? 150 TYR A CD2 1 ATOM 1202 C CE1 . TYR A 1 150 ? 87.643 10.276 -7.809 1.00 22.40 ? 150 TYR A CE1 1 ATOM 1203 C CE2 . TYR A 1 150 ? 86.652 8.324 -6.850 1.00 19.69 ? 150 TYR A CE2 1 ATOM 1204 C CZ . TYR A 1 150 ? 87.763 9.102 -7.090 1.00 21.56 ? 150 TYR A CZ 1 ATOM 1205 O OH . TYR A 1 150 ? 88.994 8.719 -6.609 1.00 23.36 ? 150 TYR A OH 1 ATOM 1206 N N . LEU A 1 151 ? 82.388 12.900 -9.971 1.00 17.08 ? 151 LEU A N 1 ATOM 1207 C CA . LEU A 1 151 ? 81.216 13.322 -10.700 1.00 20.23 ? 151 LEU A CA 1 ATOM 1208 C C . LEU A 1 151 ? 81.517 13.173 -12.155 1.00 22.58 ? 151 LEU A C 1 ATOM 1209 O O . LEU A 1 151 ? 82.205 14.009 -12.730 1.00 22.95 ? 151 LEU A O 1 ATOM 1210 C CB . LEU A 1 151 ? 80.851 14.784 -10.458 1.00 21.29 ? 151 LEU A CB 1 ATOM 1211 C CG . LEU A 1 151 ? 79.701 15.183 -11.400 1.00 18.73 ? 151 LEU A CG 1 ATOM 1212 C CD1 . LEU A 1 151 ? 78.500 14.285 -11.150 1.00 18.97 ? 151 LEU A CD1 1 ATOM 1213 C CD2 . LEU A 1 151 ? 79.325 16.620 -11.190 1.00 19.15 ? 151 LEU A CD2 1 ATOM 1214 N N . PRO A 1 152 ? 81.037 12.086 -12.769 1.00 25.07 ? 152 PRO A N 1 ATOM 1215 C CA . PRO A 1 152 ? 81.291 11.903 -14.190 1.00 26.67 ? 152 PRO A CA 1 ATOM 1216 C C . PRO A 1 152 ? 80.348 12.869 -14.900 1.00 29.32 ? 152 PRO A C 1 ATOM 1217 O O . PRO A 1 152 ? 79.174 12.978 -14.533 1.00 27.38 ? 152 PRO A O 1 ATOM 1218 C CB . PRO A 1 152 ? 80.930 10.441 -14.410 1.00 23.62 ? 152 PRO A CB 1 ATOM 1219 C CG . PRO A 1 152 ? 79.813 10.237 -13.459 1.00 24.04 ? 152 PRO A CG 1 ATOM 1220 C CD . PRO A 1 152 ? 80.323 10.926 -12.213 1.00 26.18 ? 152 PRO A CD 1 ATOM 1221 N N . PHE A 1 153 ? 80.876 13.590 -15.887 1.00 32.01 ? 153 PHE A N 1 ATOM 1222 C CA . PHE A 1 153 ? 80.087 14.554 -16.644 1.00 33.27 ? 153 PHE A CA 1 ATOM 1223 C C . PHE A 1 153 ? 80.395 14.501 -18.135 1.00 36.21 ? 153 PHE A C 1 ATOM 1224 O O . PHE A 1 153 ? 81.114 13.614 -18.611 1.00 38.04 ? 153 PHE A O 1 ATOM 1225 C CB . PHE A 1 153 ? 80.347 15.973 -16.132 1.00 29.23 ? 153 PHE A CB 1 ATOM 1226 C CG . PHE A 1 153 ? 81.728 16.507 -16.448 1.00 23.76 ? 153 PHE A CG 1 ATOM 1227 C CD1 . PHE A 1 153 ? 82.856 15.976 -15.846 1.00 23.40 ? 153 PHE A CD1 1 ATOM 1228 C CD2 . PHE A 1 153 ? 81.890 17.568 -17.325 1.00 21.80 ? 153 PHE A CD2 1 ATOM 1229 C CE1 . PHE A 1 153 ? 84.132 16.500 -16.113 1.00 22.51 ? 153 PHE A CE1 1 ATOM 1230 C CE2 . PHE A 1 153 ? 83.151 18.089 -17.591 1.00 21.88 ? 153 PHE A CE2 1 ATOM 1231 C CZ . PHE A 1 153 ? 84.274 17.553 -16.981 1.00 19.78 ? 153 PHE A CZ 1 ATOM 1232 N N . LEU A 1 154 ? 79.828 15.454 -18.866 1.00 36.41 ? 154 LEU A N 1 ATOM 1233 C CA . LEU A 1 154 ? 80.045 15.566 -20.303 1.00 33.61 ? 154 LEU A CA 1 ATOM 1234 C C . LEU A 1 154 ? 80.390 17.022 -20.521 1.00 31.75 ? 154 LEU A C 1 ATOM 1235 O O . LEU A 1 154 ? 79.516 17.873 -20.503 1.00 33.92 ? 154 LEU A O 1 ATOM 1236 C CB . LEU A 1 154 ? 78.775 15.192 -21.077 1.00 31.80 ? 154 LEU A CB 1 ATOM 1237 C CG . LEU A 1 154 ? 78.895 15.088 -22.602 1.00 29.45 ? 154 LEU A CG 1 ATOM 1238 C CD1 . LEU A 1 154 ? 80.186 14.376 -22.989 1.00 30.97 ? 154 LEU A CD1 1 ATOM 1239 C CD2 . LEU A 1 154 ? 77.699 14.341 -23.146 1.00 25.89 ? 154 LEU A CD2 1 ATOM 1240 N N . PRO A 1 155 ? 81.678 17.326 -20.709 1.00 30.75 ? 155 PRO A N 1 ATOM 1241 C CA . PRO A 1 155 ? 82.176 18.684 -20.925 1.00 31.58 ? 155 PRO A CA 1 ATOM 1242 C C . PRO A 1 155 ? 81.334 19.482 -21.903 1.00 34.95 ? 155 PRO A C 1 ATOM 1243 O O . PRO A 1 155 ? 81.394 19.271 -23.112 1.00 34.80 ? 155 PRO A O 1 ATOM 1244 C CB . PRO A 1 155 ? 83.583 18.451 -21.439 1.00 30.51 ? 155 PRO A CB 1 ATOM 1245 C CG . PRO A 1 155 ? 83.985 17.225 -20.739 1.00 32.79 ? 155 PRO A CG 1 ATOM 1246 C CD . PRO A 1 155 ? 82.763 16.353 -20.879 1.00 32.18 ? 155 PRO A CD 1 ATOM 1247 N N . SER A 1 156 ? 80.541 20.400 -21.367 1.00 38.76 ? 156 SER A N 1 ATOM 1248 C CA . SER A 1 156 ? 79.683 21.245 -22.182 1.00 40.58 ? 156 SER A CA 1 ATOM 1249 C C . SER A 1 156 ? 80.172 22.670 -22.029 1.00 42.24 ? 156 SER A C 1 ATOM 1250 O O . SER A 1 156 ? 80.613 23.073 -20.954 1.00 46.03 ? 156 SER A O 1 ATOM 1251 C CB . SER A 1 156 ? 78.233 21.137 -21.712 1.00 40.77 ? 156 SER A CB 1 ATOM 1252 O OG . SER A 1 156 ? 77.400 22.036 -22.415 1.00 43.85 ? 156 SER A OG 1 ATOM 1253 N N . THR A 1 157 ? 80.100 23.431 -23.109 1.00 43.32 ? 157 THR A N 1 ATOM 1254 C CA . THR A 1 157 ? 80.548 24.812 -23.093 1.00 44.95 ? 157 THR A CA 1 ATOM 1255 C C . THR A 1 157 ? 79.648 25.718 -22.264 1.00 46.44 ? 157 THR A C 1 ATOM 1256 O O . THR A 1 157 ? 80.096 26.714 -21.700 1.00 43.34 ? 157 THR A O 1 ATOM 1257 C CB . THR A 1 157 ? 80.610 25.360 -24.512 1.00 43.70 ? 157 THR A CB 1 ATOM 1258 O OG1 . THR A 1 157 ? 80.666 26.786 -24.467 1.00 46.52 ? 157 THR A OG1 1 ATOM 1259 C CG2 . THR A 1 157 ? 79.390 24.932 -25.292 1.00 46.84 ? 157 THR A CG2 1 ATOM 1260 N N . GLU A 1 158 ? 78.379 25.357 -22.170 1.00 50.32 ? 158 GLU A N 1 ATOM 1261 C CA . GLU A 1 158 ? 77.425 26.169 -21.436 1.00 57.21 ? 158 GLU A CA 1 ATOM 1262 C C . GLU A 1 158 ? 77.272 25.879 -19.939 1.00 58.36 ? 158 GLU A C 1 ATOM 1263 O O . GLU A 1 158 ? 76.689 26.689 -19.210 1.00 62.48 ? 158 GLU A O 1 ATOM 1264 C CB . GLU A 1 158 ? 76.063 26.065 -22.124 1.00 62.31 ? 158 GLU A CB 1 ATOM 1265 C CG . GLU A 1 158 ? 76.129 26.338 -23.622 1.00 72.73 ? 158 GLU A CG 1 ATOM 1266 C CD . GLU A 1 158 ? 76.723 27.707 -23.949 1.00 79.17 ? 158 GLU A CD 1 ATOM 1267 O OE1 . GLU A 1 158 ? 76.069 28.736 -23.661 1.00 81.71 ? 158 GLU A OE1 1 ATOM 1268 O OE2 . GLU A 1 158 ? 77.851 27.750 -24.490 1.00 80.62 ? 158 GLU A OE2 1 ATOM 1269 N N . ASP A 1 159 ? 77.798 24.747 -19.471 1.00 56.35 ? 159 ASP A N 1 ATOM 1270 C CA . ASP A 1 159 ? 77.672 24.374 -18.059 1.00 50.32 ? 159 ASP A CA 1 ATOM 1271 C C . ASP A 1 159 ? 78.802 24.792 -17.120 1.00 46.65 ? 159 ASP A C 1 ATOM 1272 O O . ASP A 1 159 ? 79.956 24.974 -17.519 1.00 46.14 ? 159 ASP A O 1 ATOM 1273 C CB . ASP A 1 159 ? 77.454 22.864 -17.943 1.00 51.48 ? 159 ASP A CB 1 ATOM 1274 C CG . ASP A 1 159 ? 76.062 22.451 -18.364 1.00 52.37 ? 159 ASP A CG 1 ATOM 1275 O OD1 . ASP A 1 159 ? 75.109 22.920 -17.719 1.00 53.15 ? 159 ASP A OD1 1 ATOM 1276 O OD2 . ASP A 1 159 ? 75.912 21.669 -19.329 1.00 53.87 ? 159 ASP A OD2 1 ATOM 1277 N N . VAL A 1 160 ? 78.444 24.932 -15.852 1.00 41.36 ? 160 VAL A N 1 ATOM 1278 C CA . VAL A 1 160 ? 79.391 25.319 -14.824 1.00 37.70 ? 160 VAL A CA 1 ATOM 1279 C C . VAL A 1 160 ? 79.170 24.435 -13.587 1.00 36.80 ? 160 VAL A C 1 ATOM 1280 O O . VAL A 1 160 ? 78.028 24.221 -13.172 1.00 38.50 ? 160 VAL A O 1 ATOM 1281 C CB . VAL A 1 160 ? 79.209 26.816 -14.488 1.00 34.76 ? 160 VAL A CB 1 ATOM 1282 C CG1 . VAL A 1 160 ? 79.169 27.031 -13.003 1.00 36.08 ? 160 VAL A CG1 1 ATOM 1283 C CG2 . VAL A 1 160 ? 80.337 27.610 -15.092 1.00 32.38 ? 160 VAL A CG2 1 ATOM 1284 N N . TYR A 1 161 ? 80.254 23.917 -13.010 1.00 30.30 ? 161 TYR A N 1 ATOM 1285 C CA . TYR A 1 161 ? 80.149 23.050 -11.841 1.00 26.92 ? 161 TYR A CA 1 ATOM 1286 C C . TYR A 1 161 ? 80.790 23.623 -10.592 1.00 27.24 ? 161 TYR A C 1 ATOM 1287 O O . TYR A 1 161 ? 81.758 24.371 -10.681 1.00 29.37 ? 161 TYR A O 1 ATOM 1288 C CB . TYR A 1 161 ? 80.805 21.694 -12.119 1.00 26.84 ? 161 TYR A CB 1 ATOM 1289 C CG . TYR A 1 161 ? 80.101 20.874 -13.158 1.00 24.53 ? 161 TYR A CG 1 ATOM 1290 C CD1 . TYR A 1 161 ? 80.353 21.069 -14.512 1.00 23.69 ? 161 TYR A CD1 1 ATOM 1291 C CD2 . TYR A 1 161 ? 79.111 19.965 -12.794 1.00 21.97 ? 161 TYR A CD2 1 ATOM 1292 C CE1 . TYR A 1 161 ? 79.627 20.390 -15.480 1.00 23.65 ? 161 TYR A CE1 1 ATOM 1293 C CE2 . TYR A 1 161 ? 78.379 19.282 -13.752 1.00 21.22 ? 161 TYR A CE2 1 ATOM 1294 C CZ . TYR A 1 161 ? 78.638 19.506 -15.092 1.00 22.07 ? 161 TYR A CZ 1 ATOM 1295 O OH . TYR A 1 161 ? 77.868 18.895 -16.044 1.00 25.61 ? 161 TYR A OH 1 ATOM 1296 N N . ASP A 1 162 ? 80.257 23.247 -9.430 1.00 25.84 ? 162 ASP A N 1 ATOM 1297 C CA . ASP A 1 162 ? 80.798 23.682 -8.141 1.00 25.67 ? 162 ASP A CA 1 ATOM 1298 C C . ASP A 1 162 ? 80.811 22.544 -7.130 1.00 25.67 ? 162 ASP A C 1 ATOM 1299 O O . ASP A 1 162 ? 79.813 21.829 -6.978 1.00 22.03 ? 162 ASP A O 1 ATOM 1300 C CB . ASP A 1 162 ? 79.965 24.808 -7.536 1.00 28.11 ? 162 ASP A CB 1 ATOM 1301 C CG . ASP A 1 162 ? 80.099 26.092 -8.286 1.00 32.51 ? 162 ASP A CG 1 ATOM 1302 O OD1 . ASP A 1 162 ? 81.235 26.610 -8.378 1.00 28.95 ? 162 ASP A OD1 1 ATOM 1303 O OD2 . ASP A 1 162 ? 79.060 26.579 -8.780 1.00 39.39 ? 162 ASP A OD2 1 ATOM 1304 N N . CYS A 1 163 ? 81.936 22.378 -6.438 1.00 24.92 ? 163 CYS A N 1 ATOM 1305 C CA . CYS A 1 163 ? 82.021 21.355 -5.403 1.00 25.08 ? 163 CYS A CA 1 ATOM 1306 C C . CYS A 1 163 ? 81.896 22.072 -4.072 1.00 25.31 ? 163 CYS A C 1 ATOM 1307 O O . CYS A 1 163 ? 82.820 22.768 -3.650 1.00 27.49 ? 163 CYS A O 1 ATOM 1308 C CB . CYS A 1 163 ? 83.355 20.607 -5.424 1.00 24.06 ? 163 CYS A CB 1 ATOM 1309 S SG . CYS A 1 163 ? 83.455 19.384 -4.067 1.00 23.73 ? 163 CYS A SG 1 ATOM 1310 N N . ARG A 1 164 ? 80.748 21.921 -3.422 1.00 23.74 ? 164 ARG A N 1 ATOM 1311 C CA . ARG A 1 164 ? 80.533 22.563 -2.140 1.00 23.04 ? 164 ARG A CA 1 ATOM 1312 C C . ARG A 1 164 ? 80.924 21.596 -1.055 1.00 22.89 ? 164 ARG A C 1 ATOM 1313 O O . ARG A 1 164 ? 80.429 20.466 -1.011 1.00 24.60 ? 164 ARG A O 1 ATOM 1314 C CB . ARG A 1 164 ? 79.074 22.959 -1.963 1.00 27.59 ? 164 ARG A CB 1 ATOM 1315 C CG . ARG A 1 164 ? 78.785 23.478 -0.579 1.00 40.78 ? 164 ARG A CG 1 ATOM 1316 C CD . ARG A 1 164 ? 77.585 24.409 -0.555 1.00 55.13 ? 164 ARG A CD 1 ATOM 1317 N NE . ARG A 1 164 ? 76.343 23.748 -0.939 1.00 62.97 ? 164 ARG A NE 1 ATOM 1318 C CZ . ARG A 1 164 ? 75.770 22.777 -0.240 1.00 67.74 ? 164 ARG A CZ 1 ATOM 1319 N NH1 . ARG A 1 164 ? 76.333 22.347 0.885 1.00 69.97 ? 164 ARG A NH1 1 ATOM 1320 N NH2 . ARG A 1 164 ? 74.626 22.247 -0.661 1.00 70.09 ? 164 ARG A NH2 1 ATOM 1321 N N . VAL A 1 165 ? 81.813 22.049 -0.179 1.00 18.61 ? 165 VAL A N 1 ATOM 1322 C CA . VAL A 1 165 ? 82.298 21.237 0.919 1.00 15.96 ? 165 VAL A CA 1 ATOM 1323 C C . VAL A 1 165 ? 82.106 21.927 2.250 1.00 19.07 ? 165 VAL A C 1 ATOM 1324 O O . VAL A 1 165 ? 82.558 23.051 2.439 1.00 21.74 ? 165 VAL A O 1 ATOM 1325 C CB . VAL A 1 165 ? 83.788 20.943 0.755 1.00 10.61 ? 165 VAL A CB 1 ATOM 1326 C CG1 . VAL A 1 165 ? 84.350 20.360 2.017 1.00 8.84 ? 165 VAL A CG1 1 ATOM 1327 C CG2 . VAL A 1 165 ? 83.988 19.986 -0.372 1.00 16.22 ? 165 VAL A CG2 1 ATOM 1328 N N . GLU A 1 166 ? 81.431 21.268 3.180 1.00 21.98 ? 166 GLU A N 1 ATOM 1329 C CA . GLU A 1 166 ? 81.267 21.864 4.491 1.00 26.15 ? 166 GLU A CA 1 ATOM 1330 C C . GLU A 1 166 ? 81.820 20.971 5.579 1.00 23.10 ? 166 GLU A C 1 ATOM 1331 O O . GLU A 1 166 ? 81.335 19.877 5.785 1.00 24.54 ? 166 GLU A O 1 ATOM 1332 C CB . GLU A 1 166 ? 79.806 22.209 4.779 1.00 33.26 ? 166 GLU A CB 1 ATOM 1333 C CG . GLU A 1 166 ? 78.760 21.317 4.172 1.00 39.78 ? 166 GLU A CG 1 ATOM 1334 C CD . GLU A 1 166 ? 77.377 21.652 4.712 1.00 47.23 ? 166 GLU A CD 1 ATOM 1335 O OE1 . GLU A 1 166 ? 76.378 21.388 4.006 1.00 54.38 ? 166 GLU A OE1 1 ATOM 1336 O OE2 . GLU A 1 166 ? 77.294 22.171 5.850 1.00 45.66 ? 166 GLU A OE2 1 ATOM 1337 N N . HIS A 1 167 ? 82.854 21.460 6.254 1.00 22.89 ? 167 HIS A N 1 ATOM 1338 C CA . HIS A 1 167 ? 83.533 20.759 7.335 1.00 21.63 ? 167 HIS A CA 1 ATOM 1339 C C . HIS A 1 167 ? 83.432 21.667 8.541 1.00 21.15 ? 167 HIS A C 1 ATOM 1340 O O . HIS A 1 167 ? 83.406 22.875 8.387 1.00 24.63 ? 167 HIS A O 1 ATOM 1341 C CB . HIS A 1 167 ? 84.998 20.549 6.958 1.00 21.94 ? 167 HIS A CB 1 ATOM 1342 C CG . HIS A 1 167 ? 85.853 20.047 8.079 1.00 22.81 ? 167 HIS A CG 1 ATOM 1343 N ND1 . HIS A 1 167 ? 85.662 18.819 8.671 1.00 26.48 ? 167 HIS A ND1 1 ATOM 1344 C CD2 . HIS A 1 167 ? 86.903 20.614 8.720 1.00 21.04 ? 167 HIS A CD2 1 ATOM 1345 C CE1 . HIS A 1 167 ? 86.556 18.652 9.629 1.00 27.22 ? 167 HIS A CE1 1 ATOM 1346 N NE2 . HIS A 1 167 ? 87.321 19.728 9.680 1.00 19.01 ? 167 HIS A NE2 1 ATOM 1347 N N . TRP A 1 168 ? 83.389 21.112 9.743 1.00 24.19 ? 168 TRP A N 1 ATOM 1348 C CA . TRP A 1 168 ? 83.259 21.958 10.929 1.00 28.18 ? 168 TRP A CA 1 ATOM 1349 C C . TRP A 1 168 ? 84.313 23.051 11.086 1.00 30.52 ? 168 TRP A C 1 ATOM 1350 O O . TRP A 1 168 ? 84.032 24.092 11.672 1.00 34.58 ? 168 TRP A O 1 ATOM 1351 C CB . TRP A 1 168 ? 83.202 21.105 12.202 1.00 26.05 ? 168 TRP A CB 1 ATOM 1352 C CG . TRP A 1 168 ? 81.918 20.342 12.319 1.00 31.20 ? 168 TRP A CG 1 ATOM 1353 C CD1 . TRP A 1 168 ? 80.667 20.789 11.989 1.00 32.77 ? 168 TRP A CD1 1 ATOM 1354 C CD2 . TRP A 1 168 ? 81.749 19.002 12.791 1.00 31.65 ? 168 TRP A CD2 1 ATOM 1355 N NE1 . TRP A 1 168 ? 79.732 19.808 12.223 1.00 32.62 ? 168 TRP A NE1 1 ATOM 1356 C CE2 . TRP A 1 168 ? 80.370 18.701 12.716 1.00 31.47 ? 168 TRP A CE2 1 ATOM 1357 C CE3 . TRP A 1 168 ? 82.626 18.025 13.269 1.00 32.92 ? 168 TRP A CE3 1 ATOM 1358 C CZ2 . TRP A 1 168 ? 79.852 17.468 13.099 1.00 31.28 ? 168 TRP A CZ2 1 ATOM 1359 C CZ3 . TRP A 1 168 ? 82.107 16.796 13.650 1.00 33.40 ? 168 TRP A CZ3 1 ATOM 1360 C CH2 . TRP A 1 168 ? 80.734 16.531 13.562 1.00 32.01 ? 168 TRP A CH2 1 ATOM 1361 N N . GLY A 1 169 ? 85.513 22.822 10.563 1.00 32.99 ? 169 GLY A N 1 ATOM 1362 C CA . GLY A 1 169 ? 86.580 23.806 10.676 1.00 31.61 ? 169 GLY A CA 1 ATOM 1363 C C . GLY A 1 169 ? 86.415 24.979 9.730 1.00 32.49 ? 169 GLY A C 1 ATOM 1364 O O . GLY A 1 169 ? 87.227 25.901 9.714 1.00 32.81 ? 169 GLY A O 1 ATOM 1365 N N . LEU A 1 170 ? 85.364 24.936 8.923 1.00 33.91 ? 170 LEU A N 1 ATOM 1366 C CA . LEU A 1 170 ? 85.080 26.010 7.984 1.00 33.12 ? 170 LEU A CA 1 ATOM 1367 C C . LEU A 1 170 ? 83.978 26.849 8.586 1.00 35.05 ? 170 LEU A C 1 ATOM 1368 O O . LEU A 1 170 ? 83.030 26.324 9.168 1.00 32.95 ? 170 LEU A O 1 ATOM 1369 C CB . LEU A 1 170 ? 84.609 25.461 6.636 1.00 27.74 ? 170 LEU A CB 1 ATOM 1370 C CG . LEU A 1 170 ? 85.617 24.677 5.802 1.00 20.63 ? 170 LEU A CG 1 ATOM 1371 C CD1 . LEU A 1 170 ? 84.977 24.290 4.472 1.00 14.38 ? 170 LEU A CD1 1 ATOM 1372 C CD2 . LEU A 1 170 ? 86.860 25.520 5.584 1.00 15.80 ? 170 LEU A CD2 1 ATOM 1373 N N . ASP A 1 171 ? 84.110 28.158 8.441 1.00 40.45 ? 171 ASP A N 1 ATOM 1374 C CA . ASP A 1 171 ? 83.128 29.088 8.969 1.00 45.77 ? 171 ASP A CA 1 ATOM 1375 C C . ASP A 1 171 ? 81.827 28.960 8.173 1.00 44.47 ? 171 ASP A C 1 ATOM 1376 O O . ASP A 1 171 ? 80.764 28.718 8.743 1.00 43.32 ? 171 ASP A O 1 ATOM 1377 C CB . ASP A 1 171 ? 83.716 30.502 8.922 1.00 52.44 ? 171 ASP A CB 1 ATOM 1378 C CG . ASP A 1 171 ? 84.979 30.637 9.794 1.00 58.49 ? 171 ASP A CG 1 ATOM 1379 O OD1 . ASP A 1 171 ? 84.855 30.667 11.046 1.00 58.81 ? 171 ASP A OD1 1 ATOM 1380 O OD2 . ASP A 1 171 ? 86.096 30.695 9.226 1.00 59.72 ? 171 ASP A OD2 1 ATOM 1381 N N . GLU A 1 172 ? 81.906 29.114 6.860 1.00 43.51 ? 172 GLU A N 1 ATOM 1382 C CA . GLU A 1 172 ? 80.727 28.940 6.028 1.00 47.27 ? 172 GLU A CA 1 ATOM 1383 C C . GLU A 1 172 ? 81.158 27.875 5.016 1.00 45.66 ? 172 GLU A C 1 ATOM 1384 O O . GLU A 1 172 ? 82.345 27.565 4.915 1.00 45.13 ? 172 GLU A O 1 ATOM 1385 C CB . GLU A 1 172 ? 80.343 30.248 5.319 1.00 54.10 ? 172 GLU A CB 1 ATOM 1386 C CG . GLU A 1 172 ? 81.256 30.635 4.151 1.00 69.59 ? 172 GLU A CG 1 ATOM 1387 C CD . GLU A 1 172 ? 82.351 31.632 4.530 1.00 77.59 ? 172 GLU A CD 1 ATOM 1388 O OE1 . GLU A 1 172 ? 82.862 31.552 5.672 1.00 81.81 ? 172 GLU A OE1 1 ATOM 1389 O OE2 . GLU A 1 172 ? 82.709 32.482 3.675 1.00 77.33 ? 172 GLU A OE2 1 ATOM 1390 N N . PRO A 1 173 ? 80.208 27.283 4.272 1.00 43.46 ? 173 PRO A N 1 ATOM 1391 C CA . PRO A 1 173 ? 80.575 26.260 3.291 1.00 38.61 ? 173 PRO A CA 1 ATOM 1392 C C . PRO A 1 173 ? 81.672 26.765 2.382 1.00 34.87 ? 173 PRO A C 1 ATOM 1393 O O . PRO A 1 173 ? 81.985 27.954 2.370 1.00 35.57 ? 173 PRO A O 1 ATOM 1394 C CB . PRO A 1 173 ? 79.277 26.025 2.530 1.00 41.57 ? 173 PRO A CB 1 ATOM 1395 C CG . PRO A 1 173 ? 78.244 26.239 3.568 1.00 46.29 ? 173 PRO A CG 1 ATOM 1396 C CD . PRO A 1 173 ? 78.750 27.488 4.285 1.00 46.33 ? 173 PRO A CD 1 ATOM 1397 N N . LEU A 1 174 ? 82.241 25.856 1.607 1.00 31.58 ? 174 LEU A N 1 ATOM 1398 C CA . LEU A 1 174 ? 83.323 26.190 0.700 1.00 29.09 ? 174 LEU A CA 1 ATOM 1399 C C . LEU A 1 174 ? 82.999 25.714 -0.704 1.00 29.66 ? 174 LEU A C 1 ATOM 1400 O O . LEU A 1 174 ? 82.523 24.600 -0.905 1.00 32.02 ? 174 LEU A O 1 ATOM 1401 C CB . LEU A 1 174 ? 84.605 25.531 1.197 1.00 27.64 ? 174 LEU A CB 1 ATOM 1402 C CG . LEU A 1 174 ? 85.916 25.753 0.459 1.00 29.24 ? 174 LEU A CG 1 ATOM 1403 C CD1 . LEU A 1 174 ? 86.303 27.214 0.492 1.00 28.24 ? 174 LEU A CD1 1 ATOM 1404 C CD2 . LEU A 1 174 ? 86.984 24.908 1.128 1.00 32.27 ? 174 LEU A CD2 1 ATOM 1405 N N . LEU A 1 175 ? 83.250 26.565 -1.683 1.00 31.24 ? 175 LEU A N 1 ATOM 1406 C CA . LEU A 1 175 ? 82.980 26.204 -3.065 1.00 33.13 ? 175 LEU A CA 1 ATOM 1407 C C . LEU A 1 175 ? 84.210 26.262 -3.944 1.00 35.91 ? 175 LEU A C 1 ATOM 1408 O O . LEU A 1 175 ? 84.909 27.285 -3.995 1.00 40.44 ? 175 LEU A O 1 ATOM 1409 C CB . LEU A 1 175 ? 81.957 27.145 -3.689 1.00 29.42 ? 175 LEU A CB 1 ATOM 1410 C CG . LEU A 1 175 ? 80.539 27.192 -3.172 1.00 29.62 ? 175 LEU A CG 1 ATOM 1411 C CD1 . LEU A 1 175 ? 79.804 28.276 -3.909 1.00 33.63 ? 175 LEU A CD1 1 ATOM 1412 C CD2 . LEU A 1 175 ? 79.872 25.872 -3.395 1.00 36.56 ? 175 LEU A CD2 1 ATOM 1413 N N . LYS A 1 176 ? 84.493 25.163 -4.624 1.00 33.06 ? 176 LYS A N 1 ATOM 1414 C CA . LYS A 1 176 ? 85.582 25.189 -5.562 1.00 30.66 ? 176 LYS A CA 1 ATOM 1415 C C . LYS A 1 176 ? 84.795 25.182 -6.844 1.00 30.19 ? 176 LYS A C 1 ATOM 1416 O O . LYS A 1 176 ? 83.824 24.430 -6.999 1.00 25.56 ? 176 LYS A O 1 ATOM 1417 C CB . LYS A 1 176 ? 86.483 23.983 -5.420 1.00 33.84 ? 176 LYS A CB 1 ATOM 1418 C CG . LYS A 1 176 ? 87.484 24.166 -4.309 1.00 36.92 ? 176 LYS A CG 1 ATOM 1419 C CD . LYS A 1 176 ? 88.371 25.361 -4.563 1.00 40.39 ? 176 LYS A CD 1 ATOM 1420 C CE . LYS A 1 176 ? 89.209 25.655 -3.330 1.00 46.50 ? 176 LYS A CE 1 ATOM 1421 N NZ . LYS A 1 176 ? 90.121 26.818 -3.520 1.00 53.19 ? 176 LYS A NZ 1 ATOM 1422 N N . HIS A 1 177 ? 85.197 26.067 -7.741 1.00 30.34 ? 177 HIS A N 1 ATOM 1423 C CA . HIS A 1 177 ? 84.511 26.253 -9.006 1.00 30.06 ? 177 HIS A CA 1 ATOM 1424 C C . HIS A 1 177 ? 85.238 25.623 -10.205 1.00 28.30 ? 177 HIS A C 1 ATOM 1425 O O . HIS A 1 177 ? 86.470 25.541 -10.229 1.00 29.89 ? 177 HIS A O 1 ATOM 1426 C CB . HIS A 1 177 ? 84.329 27.771 -9.197 1.00 30.97 ? 177 HIS A CB 1 ATOM 1427 C CG . HIS A 1 177 ? 83.484 28.152 -10.371 1.00 28.13 ? 177 HIS A CG 1 ATOM 1428 N ND1 . HIS A 1 177 ? 82.139 27.857 -10.448 1.00 25.41 ? 177 HIS A ND1 1 ATOM 1429 C CD2 . HIS A 1 177 ? 83.803 28.777 -11.529 1.00 22.65 ? 177 HIS A CD2 1 ATOM 1430 C CE1 . HIS A 1 177 ? 81.670 28.276 -11.609 1.00 26.47 ? 177 HIS A CE1 1 ATOM 1431 N NE2 . HIS A 1 177 ? 82.659 28.836 -12.284 1.00 26.70 ? 177 HIS A NE2 1 ATOM 1432 N N . TRP A 1 178 ? 84.467 25.164 -11.186 1.00 23.49 ? 178 TRP A N 1 ATOM 1433 C CA . TRP A 1 178 ? 85.031 24.586 -12.395 1.00 24.61 ? 178 TRP A CA 1 ATOM 1434 C C . TRP A 1 178 ? 84.080 24.800 -13.549 1.00 30.02 ? 178 TRP A C 1 ATOM 1435 O O . TRP A 1 178 ? 82.860 24.798 -13.362 1.00 31.10 ? 178 TRP A O 1 ATOM 1436 C CB . TRP A 1 178 ? 85.249 23.083 -12.263 1.00 23.95 ? 178 TRP A CB 1 ATOM 1437 C CG . TRP A 1 178 ? 85.990 22.504 -13.447 1.00 16.03 ? 178 TRP A CG 1 ATOM 1438 C CD1 . TRP A 1 178 ? 87.341 22.441 -13.603 1.00 12.21 ? 178 TRP A CD1 1 ATOM 1439 C CD2 . TRP A 1 178 ? 85.423 21.999 -14.665 1.00 10.13 ? 178 TRP A CD2 1 ATOM 1440 N NE1 . TRP A 1 178 ? 87.652 21.936 -14.833 1.00 11.42 ? 178 TRP A NE1 1 ATOM 1441 C CE2 . TRP A 1 178 ? 86.495 21.655 -15.510 1.00 10.62 ? 178 TRP A CE2 1 ATOM 1442 C CE3 . TRP A 1 178 ? 84.114 21.808 -15.125 1.00 9.23 ? 178 TRP A CE3 1 ATOM 1443 C CZ2 . TRP A 1 178 ? 86.302 21.127 -16.798 1.00 8.96 ? 178 TRP A CZ2 1 ATOM 1444 C CZ3 . TRP A 1 178 ? 83.922 21.286 -16.404 1.00 5.76 ? 178 TRP A CZ3 1 ATOM 1445 C CH2 . TRP A 1 178 ? 85.014 20.952 -17.223 1.00 6.85 ? 178 TRP A CH2 1 ATOM 1446 N N . GLU A 1 179 ? 84.645 24.966 -14.741 1.00 34.92 ? 179 GLU A N 1 ATOM 1447 C CA . GLU A 1 179 ? 83.865 25.150 -15.958 1.00 40.92 ? 179 GLU A CA 1 ATOM 1448 C C . GLU A 1 179 ? 84.806 25.046 -17.142 1.00 44.82 ? 179 GLU A C 1 ATOM 1449 O O . GLU A 1 179 ? 86.009 25.266 -17.001 1.00 38.78 ? 179 GLU A O 1 ATOM 1450 C CB . GLU A 1 179 ? 83.169 26.511 -15.965 1.00 43.52 ? 179 GLU A CB 1 ATOM 1451 C CG . GLU A 1 179 ? 84.114 27.703 -15.955 1.00 45.21 ? 179 GLU A CG 1 ATOM 1452 C CD . GLU A 1 179 ? 83.375 29.023 -15.966 1.00 45.21 ? 179 GLU A CD 1 ATOM 1453 O OE1 . GLU A 1 179 ? 82.702 29.350 -14.966 1.00 41.13 ? 179 GLU A OE1 1 ATOM 1454 O OE2 . GLU A 1 179 ? 83.464 29.730 -16.987 1.00 49.27 ? 179 GLU A OE2 1 ATOM 1455 N N . PHE A 1 180 ? 84.257 24.705 -18.306 1.00 52.58 ? 180 PHE A N 1 ATOM 1456 C CA . PHE A 1 180 ? 85.071 24.570 -19.499 1.00 59.17 ? 180 PHE A CA 1 ATOM 1457 C C . PHE A 1 180 ? 85.644 25.912 -19.919 1.00 65.04 ? 180 PHE A C 1 ATOM 1458 O O . PHE A 1 180 ? 84.914 26.895 -20.047 1.00 64.68 ? 180 PHE A O 1 ATOM 1459 C CB . PHE A 1 180 ? 84.261 23.978 -20.643 1.00 57.79 ? 180 PHE A CB 1 ATOM 1460 C CG . PHE A 1 180 ? 85.113 23.422 -21.743 1.00 63.74 ? 180 PHE A CG 1 ATOM 1461 C CD1 . PHE A 1 180 ? 84.540 22.914 -22.904 1.00 65.15 ? 180 PHE A CD1 1 ATOM 1462 C CD2 . PHE A 1 180 ? 86.503 23.400 -21.615 1.00 65.73 ? 180 PHE A CD2 1 ATOM 1463 C CE1 . PHE A 1 180 ? 85.339 22.393 -23.923 1.00 65.04 ? 180 PHE A CE1 1 ATOM 1464 C CE2 . PHE A 1 180 ? 87.309 22.883 -22.624 1.00 66.33 ? 180 PHE A CE2 1 ATOM 1465 C CZ . PHE A 1 180 ? 86.725 22.378 -23.782 1.00 67.50 ? 180 PHE A CZ 1 ATOM 1466 N N . ASP A 1 181 ? 86.956 25.937 -20.139 1.00 74.35 ? 181 ASP A N 1 ATOM 1467 C CA . ASP A 1 181 ? 87.683 27.152 -20.525 1.00 84.99 ? 181 ASP A CA 1 ATOM 1468 C C . ASP A 1 181 ? 88.009 27.958 -19.262 1.00 88.85 ? 181 ASP A C 1 ATOM 1469 O O . ASP A 1 181 ? 87.413 29.011 -19.017 1.00 89.47 ? 181 ASP A O 1 ATOM 1470 C CB . ASP A 1 181 ? 86.855 28.006 -21.503 1.00 89.17 ? 181 ASP A CB 1 ATOM 1471 C CG . ASP A 1 181 ? 86.825 27.428 -22.920 1.00 93.94 ? 181 ASP A CG 1 ATOM 1472 O OD1 . ASP A 1 181 ? 87.878 27.435 -23.599 1.00 96.21 ? 181 ASP A OD1 1 ATOM 1473 O OD2 . ASP A 1 181 ? 85.748 26.965 -23.355 1.00 94.39 ? 181 ASP A OD2 1 ATOM 1474 N N . ALA A 1 182 ? 88.956 27.436 -18.477 1.00 92.97 ? 182 ALA A N 1 ATOM 1475 C CA . ALA A 1 182 ? 89.420 28.016 -17.206 1.00 94.61 ? 182 ALA A CA 1 ATOM 1476 C C . ALA A 1 182 ? 88.745 29.319 -16.759 1.00 96.10 ? 182 ALA A C 1 ATOM 1477 O O . ALA A 1 182 ? 88.139 29.327 -15.664 1.00 97.25 ? 182 ALA A O 1 ATOM 1478 C CB . ALA A 1 182 ? 90.941 28.199 -17.248 1.00 93.29 ? 182 ALA A CB 1 ATOM 1479 O OXT . ALA A 1 182 ? 88.827 30.321 -17.499 1.00 98.39 ? 182 ALA A OXT 1 ATOM 1480 N N . ASP B 2 2 ? 77.446 23.180 14.582 1.00 65.41 ? 2 ASP B N 1 ATOM 1481 C CA . ASP B 2 2 ? 77.582 22.209 15.706 1.00 66.51 ? 2 ASP B CA 1 ATOM 1482 C C . ASP B 2 2 ? 78.951 22.354 16.372 1.00 67.27 ? 2 ASP B C 1 ATOM 1483 O O . ASP B 2 2 ? 79.985 22.257 15.708 1.00 67.33 ? 2 ASP B O 1 ATOM 1484 C CB . ASP B 2 2 ? 77.398 20.783 15.183 1.00 64.93 ? 2 ASP B CB 1 ATOM 1485 C CG . ASP B 2 2 ? 77.276 19.770 16.299 1.00 65.37 ? 2 ASP B CG 1 ATOM 1486 O OD1 . ASP B 2 2 ? 76.949 18.599 16.014 1.00 67.27 ? 2 ASP B OD1 1 ATOM 1487 O OD2 . ASP B 2 2 ? 77.508 20.146 17.465 1.00 62.91 ? 2 ASP B OD2 1 ATOM 1488 N N . THR B 2 3 ? 78.954 22.579 17.686 1.00 67.64 ? 3 THR B N 1 ATOM 1489 C CA . THR B 2 3 ? 80.201 22.768 18.436 1.00 68.81 ? 3 THR B CA 1 ATOM 1490 C C . THR B 2 3 ? 80.511 21.772 19.554 1.00 64.39 ? 3 THR B C 1 ATOM 1491 O O . THR B 2 3 ? 81.576 21.853 20.173 1.00 61.63 ? 3 THR B O 1 ATOM 1492 C CB . THR B 2 3 ? 80.261 24.172 19.069 1.00 74.96 ? 3 THR B CB 1 ATOM 1493 O OG1 . THR B 2 3 ? 78.979 24.484 19.636 1.00 81.05 ? 3 THR B OG1 1 ATOM 1494 C CG2 . THR B 2 3 ? 80.670 25.229 18.034 1.00 76.00 ? 3 THR B CG2 1 ATOM 1495 N N . ARG B 2 4 ? 79.593 20.854 19.838 1.00 60.22 ? 4 ARG B N 1 ATOM 1496 C CA . ARG B 2 4 ? 79.851 19.874 20.880 1.00 56.51 ? 4 ARG B CA 1 ATOM 1497 C C . ARG B 2 4 ? 81.133 19.135 20.512 1.00 54.41 ? 4 ARG B C 1 ATOM 1498 O O . ARG B 2 4 ? 81.278 18.636 19.396 1.00 56.20 ? 4 ARG B O 1 ATOM 1499 C CB . ARG B 2 4 ? 78.683 18.901 20.996 1.00 57.34 ? 4 ARG B CB 1 ATOM 1500 C CG . ARG B 2 4 ? 78.120 18.494 19.667 1.00 61.68 ? 4 ARG B CG 1 ATOM 1501 C CD . ARG B 2 4 ? 77.109 17.379 19.809 1.00 68.76 ? 4 ARG B CD 1 ATOM 1502 N NE . ARG B 2 4 ? 76.620 16.958 18.500 1.00 71.79 ? 4 ARG B NE 1 ATOM 1503 C CZ . ARG B 2 4 ? 76.061 15.780 18.248 1.00 72.69 ? 4 ARG B CZ 1 ATOM 1504 N NH1 . ARG B 2 4 ? 75.910 14.880 19.218 1.00 71.50 ? 4 ARG B NH1 1 ATOM 1505 N NH2 . ARG B 2 4 ? 75.658 15.502 17.017 1.00 72.67 ? 4 ARG B NH2 1 ATOM 1506 N N . PRO B 2 5 ? 82.084 19.066 21.450 1.00 50.73 ? 5 PRO B N 1 ATOM 1507 C CA . PRO B 2 5 ? 83.393 18.423 21.331 1.00 48.83 ? 5 PRO B CA 1 ATOM 1508 C C . PRO B 2 5 ? 83.381 17.035 20.727 1.00 47.57 ? 5 PRO B C 1 ATOM 1509 O O . PRO B 2 5 ? 82.476 16.253 20.974 1.00 49.52 ? 5 PRO B O 1 ATOM 1510 C CB . PRO B 2 5 ? 83.879 18.382 22.768 1.00 50.60 ? 5 PRO B CB 1 ATOM 1511 C CG . PRO B 2 5 ? 83.278 19.588 23.352 1.00 51.83 ? 5 PRO B CG 1 ATOM 1512 C CD . PRO B 2 5 ? 81.871 19.519 22.830 1.00 51.28 ? 5 PRO B CD 1 ATOM 1513 N N . ARG B 2 6 ? 84.405 16.734 19.942 1.00 46.33 ? 6 ARG B N 1 ATOM 1514 C CA . ARG B 2 6 ? 84.545 15.423 19.331 1.00 41.45 ? 6 ARG B CA 1 ATOM 1515 C C . ARG B 2 6 ? 85.846 14.811 19.823 1.00 41.77 ? 6 ARG B C 1 ATOM 1516 O O . ARG B 2 6 ? 86.854 15.517 19.981 1.00 38.88 ? 6 ARG B O 1 ATOM 1517 C CB . ARG B 2 6 ? 84.610 15.533 17.814 1.00 40.59 ? 6 ARG B CB 1 ATOM 1518 C CG . ARG B 2 6 ? 83.367 15.103 17.116 1.00 35.53 ? 6 ARG B CG 1 ATOM 1519 C CD . ARG B 2 6 ? 82.305 16.122 17.303 1.00 34.54 ? 6 ARG B CD 1 ATOM 1520 N NE . ARG B 2 6 ? 81.084 15.699 16.646 1.00 39.71 ? 6 ARG B NE 1 ATOM 1521 C CZ . ARG B 2 6 ? 79.992 16.444 16.573 1.00 42.54 ? 6 ARG B CZ 1 ATOM 1522 N NH1 . ARG B 2 6 ? 79.989 17.651 17.121 1.00 45.46 ? 6 ARG B NH1 1 ATOM 1523 N NH2 . ARG B 2 6 ? 78.905 15.980 15.967 1.00 41.73 ? 6 ARG B NH2 1 ATOM 1524 N N . PHE B 2 7 ? 85.819 13.501 20.062 1.00 40.86 ? 7 PHE B N 1 ATOM 1525 C CA . PHE B 2 7 ? 86.999 12.766 20.516 1.00 39.53 ? 7 PHE B CA 1 ATOM 1526 C C . PHE B 2 7 ? 87.282 11.658 19.513 1.00 36.63 ? 7 PHE B C 1 ATOM 1527 O O . PHE B 2 7 ? 86.404 10.848 19.193 1.00 36.23 ? 7 PHE B O 1 ATOM 1528 C CB . PHE B 2 7 ? 86.757 12.221 21.922 1.00 40.11 ? 7 PHE B CB 1 ATOM 1529 C CG . PHE B 2 7 ? 86.476 13.303 22.924 1.00 42.25 ? 7 PHE B CG 1 ATOM 1530 C CD1 . PHE B 2 7 ? 87.487 14.171 23.327 1.00 42.67 ? 7 PHE B CD1 1 ATOM 1531 C CD2 . PHE B 2 7 ? 85.186 13.515 23.398 1.00 39.55 ? 7 PHE B CD2 1 ATOM 1532 C CE1 . PHE B 2 7 ? 87.211 15.231 24.179 1.00 41.47 ? 7 PHE B CE1 1 ATOM 1533 C CE2 . PHE B 2 7 ? 84.902 14.575 24.250 1.00 37.21 ? 7 PHE B CE2 1 ATOM 1534 C CZ . PHE B 2 7 ? 85.914 15.433 24.640 1.00 39.97 ? 7 PHE B CZ 1 ATOM 1535 N N . LEU B 2 8 ? 88.509 11.636 19.006 1.00 31.93 ? 8 LEU B N 1 ATOM 1536 C CA . LEU B 2 8 ? 88.868 10.659 17.995 1.00 31.80 ? 8 LEU B CA 1 ATOM 1537 C C . LEU B 2 8 ? 89.942 9.652 18.386 1.00 30.72 ? 8 LEU B C 1 ATOM 1538 O O . LEU B 2 8 ? 90.961 10.011 18.971 1.00 28.04 ? 8 LEU B O 1 ATOM 1539 C CB . LEU B 2 8 ? 89.307 11.393 16.727 1.00 30.72 ? 8 LEU B CB 1 ATOM 1540 C CG . LEU B 2 8 ? 89.285 10.634 15.395 1.00 28.22 ? 8 LEU B CG 1 ATOM 1541 C CD1 . LEU B 2 8 ? 87.844 10.275 15.022 1.00 17.76 ? 8 LEU B CD1 1 ATOM 1542 C CD2 . LEU B 2 8 ? 89.945 11.494 14.314 1.00 23.23 ? 8 LEU B CD2 1 ATOM 1543 N N . GLN B 2 9 ? 89.691 8.387 18.052 1.00 29.96 ? 9 GLN B N 1 ATOM 1544 C CA . GLN B 2 9 ? 90.633 7.308 18.307 1.00 32.87 ? 9 GLN B CA 1 ATOM 1545 C C . GLN B 2 9 ? 91.042 6.863 16.930 1.00 32.35 ? 9 GLN B C 1 ATOM 1546 O O . GLN B 2 9 ? 90.189 6.641 16.070 1.00 32.41 ? 9 GLN B O 1 ATOM 1547 C CB . GLN B 2 9 ? 89.961 6.141 19.028 1.00 38.62 ? 9 GLN B CB 1 ATOM 1548 C CG . GLN B 2 9 ? 90.620 5.745 20.353 1.00 44.91 ? 9 GLN B CG 1 ATOM 1549 C CD . GLN B 2 9 ? 91.831 4.860 20.187 1.00 45.77 ? 9 GLN B CD 1 ATOM 1550 O OE1 . GLN B 2 9 ? 91.706 3.672 19.878 1.00 43.18 ? 9 GLN B OE1 1 ATOM 1551 N NE2 . GLN B 2 9 ? 93.018 5.434 20.396 1.00 48.33 ? 9 GLN B NE2 1 ATOM 1552 N N . GLN B 2 10 ? 92.342 6.743 16.711 1.00 31.32 ? 10 GLN B N 1 ATOM 1553 C CA . GLN B 2 10 ? 92.832 6.327 15.409 1.00 31.73 ? 10 GLN B CA 1 ATOM 1554 C C . GLN B 2 10 ? 93.937 5.278 15.610 1.00 32.60 ? 10 GLN B C 1 ATOM 1555 O O . GLN B 2 10 ? 94.951 5.544 16.263 1.00 30.00 ? 10 GLN B O 1 ATOM 1556 C CB . GLN B 2 10 ? 93.349 7.561 14.658 1.00 29.80 ? 10 GLN B CB 1 ATOM 1557 C CG . GLN B 2 10 ? 93.295 7.487 13.131 1.00 32.57 ? 10 GLN B CG 1 ATOM 1558 C CD . GLN B 2 10 ? 93.530 8.851 12.461 1.00 35.16 ? 10 GLN B CD 1 ATOM 1559 O OE1 . GLN B 2 10 ? 93.782 8.945 11.249 1.00 32.24 ? 10 GLN B OE1 1 ATOM 1560 N NE2 . GLN B 2 10 ? 93.435 9.914 13.253 1.00 37.17 ? 10 GLN B NE2 1 ATOM 1561 N N . ASP B 2 11 ? 93.714 4.076 15.073 1.00 32.37 ? 11 ASP B N 1 ATOM 1562 C CA . ASP B 2 11 ? 94.672 2.971 15.171 1.00 29.12 ? 11 ASP B CA 1 ATOM 1563 C C . ASP B 2 11 ? 95.287 2.631 13.821 1.00 29.10 ? 11 ASP B C 1 ATOM 1564 O O . ASP B 2 11 ? 94.579 2.387 12.836 1.00 27.88 ? 11 ASP B O 1 ATOM 1565 C CB . ASP B 2 11 ? 93.992 1.729 15.736 1.00 28.91 ? 11 ASP B CB 1 ATOM 1566 C CG . ASP B 2 11 ? 94.227 1.570 17.208 1.00 33.95 ? 11 ASP B CG 1 ATOM 1567 O OD1 . ASP B 2 11 ? 95.399 1.410 17.605 1.00 38.00 ? 11 ASP B OD1 1 ATOM 1568 O OD2 . ASP B 2 11 ? 93.246 1.610 17.973 1.00 38.91 ? 11 ASP B OD2 1 ATOM 1569 N N . LYS B 2 12 ? 96.612 2.612 13.773 1.00 28.05 ? 12 LYS B N 1 ATOM 1570 C CA . LYS B 2 12 ? 97.294 2.311 12.529 1.00 30.11 ? 12 LYS B CA 1 ATOM 1571 C C . LYS B 2 12 ? 98.316 1.199 12.670 1.00 33.49 ? 12 LYS B C 1 ATOM 1572 O O . LYS B 2 12 ? 99.196 1.268 13.530 1.00 32.48 ? 12 LYS B O 1 ATOM 1573 C CB . LYS B 2 12 ? 97.977 3.568 11.988 1.00 27.43 ? 12 LYS B CB 1 ATOM 1574 C CG . LYS B 2 12 ? 97.003 4.598 11.452 1.00 27.55 ? 12 LYS B CG 1 ATOM 1575 C CD . LYS B 2 12 ? 97.698 5.860 10.964 1.00 22.30 ? 12 LYS B CD 1 ATOM 1576 C CE . LYS B 2 12 ? 96.689 6.813 10.344 1.00 18.57 ? 12 LYS B CE 1 ATOM 1577 N NZ . LYS B 2 12 ? 97.315 8.075 9.886 1.00 19.46 ? 12 LYS B NZ 1 ATOM 1578 N N . TYR B 2 13 ? 98.171 0.174 11.825 1.00 36.14 ? 13 TYR B N 1 ATOM 1579 C CA . TYR B 2 13 ? 99.080 -0.976 11.774 1.00 36.21 ? 13 TYR B CA 1 ATOM 1580 C C . TYR B 2 13 ? 99.795 -0.894 10.417 1.00 37.20 ? 13 TYR B C 1 ATOM 1581 O O . TYR B 2 13 ? 99.196 -1.153 9.356 1.00 35.48 ? 13 TYR B O 1 ATOM 1582 C CB . TYR B 2 13 ? 98.302 -2.301 11.891 1.00 35.22 ? 13 TYR B CB 1 ATOM 1583 C CG . TYR B 2 13 ? 97.436 -2.400 13.134 1.00 32.16 ? 13 TYR B CG 1 ATOM 1584 C CD1 . TYR B 2 13 ? 96.064 -2.162 13.067 1.00 31.65 ? 13 TYR B CD1 1 ATOM 1585 C CD2 . TYR B 2 13 ? 97.999 -2.646 14.391 1.00 29.28 ? 13 TYR B CD2 1 ATOM 1586 C CE1 . TYR B 2 13 ? 95.274 -2.151 14.218 1.00 27.31 ? 13 TYR B CE1 1 ATOM 1587 C CE2 . TYR B 2 13 ? 97.216 -2.637 15.550 1.00 24.84 ? 13 TYR B CE2 1 ATOM 1588 C CZ . TYR B 2 13 ? 95.859 -2.379 15.451 1.00 25.57 ? 13 TYR B CZ 1 ATOM 1589 O OH . TYR B 2 13 ? 95.087 -2.275 16.576 1.00 23.69 ? 13 TYR B OH 1 ATOM 1590 N N . GLU B 2 14 ? 101.072 -0.522 10.454 1.00 35.24 ? 14 GLU B N 1 ATOM 1591 C CA . GLU B 2 14 ? 101.846 -0.372 9.229 1.00 37.16 ? 14 GLU B CA 1 ATOM 1592 C C . GLU B 2 14 ? 102.912 -1.441 9.005 1.00 37.78 ? 14 GLU B C 1 ATOM 1593 O O . GLU B 2 14 ? 103.652 -1.820 9.918 1.00 37.87 ? 14 GLU B O 1 ATOM 1594 C CB . GLU B 2 14 ? 102.505 1.003 9.209 1.00 36.93 ? 14 GLU B CB 1 ATOM 1595 C CG . GLU B 2 14 ? 101.585 2.108 9.657 1.00 44.05 ? 14 GLU B CG 1 ATOM 1596 C CD . GLU B 2 14 ? 102.307 3.426 9.854 1.00 49.96 ? 14 GLU B CD 1 ATOM 1597 O OE1 . GLU B 2 14 ? 103.427 3.417 10.408 1.00 50.66 ? 14 GLU B OE1 1 ATOM 1598 O OE2 . GLU B 2 14 ? 101.749 4.475 9.470 1.00 55.47 ? 14 GLU B OE2 1 ATOM 1599 N N . CYS B 2 15 ? 102.969 -1.923 7.770 1.00 36.60 ? 15 CYS B N 1 ATOM 1600 C CA . CYS B 2 15 ? 103.931 -2.927 7.355 1.00 35.16 ? 15 CYS B CA 1 ATOM 1601 C C . CYS B 2 15 ? 104.766 -2.265 6.283 1.00 35.69 ? 15 CYS B C 1 ATOM 1602 O O . CYS B 2 15 ? 104.295 -2.021 5.183 1.00 37.08 ? 15 CYS B O 1 ATOM 1603 C CB . CYS B 2 15 ? 103.228 -4.149 6.756 1.00 36.63 ? 15 CYS B CB 1 ATOM 1604 S SG . CYS B 2 15 ? 102.424 -5.301 7.917 1.00 37.17 ? 15 CYS B SG 1 ATOM 1605 N N . HIS B 2 16 ? 106.008 -1.961 6.607 1.00 38.07 ? 16 HIS B N 1 ATOM 1606 C CA . HIS B 2 16 ? 106.894 -1.319 5.654 1.00 41.65 ? 16 HIS B CA 1 ATOM 1607 C C . HIS B 2 16 ? 107.847 -2.324 5.005 1.00 43.27 ? 16 HIS B C 1 ATOM 1608 O O . HIS B 2 16 ? 108.618 -2.995 5.689 1.00 47.78 ? 16 HIS B O 1 ATOM 1609 C CB . HIS B 2 16 ? 107.672 -0.225 6.370 1.00 42.62 ? 16 HIS B CB 1 ATOM 1610 C CG . HIS B 2 16 ? 106.798 0.829 6.962 1.00 44.24 ? 16 HIS B CG 1 ATOM 1611 N ND1 . HIS B 2 16 ? 106.326 1.894 6.230 1.00 47.81 ? 16 HIS B ND1 1 ATOM 1612 C CD2 . HIS B 2 16 ? 106.259 0.951 8.197 1.00 46.88 ? 16 HIS B CD2 1 ATOM 1613 C CE1 . HIS B 2 16 ? 105.532 2.628 6.989 1.00 50.05 ? 16 HIS B CE1 1 ATOM 1614 N NE2 . HIS B 2 16 ? 105.474 2.077 8.187 1.00 48.10 ? 16 HIS B NE2 1 ATOM 1615 N N . PHE B 2 17 ? 107.800 -2.416 3.684 1.00 41.52 ? 17 PHE B N 1 ATOM 1616 C CA . PHE B 2 17 ? 108.648 -3.345 2.963 1.00 43.06 ? 17 PHE B CA 1 ATOM 1617 C C . PHE B 2 17 ? 109.774 -2.679 2.176 1.00 47.98 ? 17 PHE B C 1 ATOM 1618 O O . PHE B 2 17 ? 109.540 -1.753 1.409 1.00 50.26 ? 17 PHE B O 1 ATOM 1619 C CB . PHE B 2 17 ? 107.794 -4.150 2.004 1.00 41.15 ? 17 PHE B CB 1 ATOM 1620 C CG . PHE B 2 17 ? 106.662 -4.876 2.660 1.00 42.29 ? 17 PHE B CG 1 ATOM 1621 C CD1 . PHE B 2 17 ? 106.900 -5.996 3.438 1.00 44.50 ? 17 PHE B CD1 1 ATOM 1622 C CD2 . PHE B 2 17 ? 105.349 -4.467 2.466 1.00 42.77 ? 17 PHE B CD2 1 ATOM 1623 C CE1 . PHE B 2 17 ? 105.848 -6.706 4.009 1.00 45.95 ? 17 PHE B CE1 1 ATOM 1624 C CE2 . PHE B 2 17 ? 104.288 -5.168 3.032 1.00 41.04 ? 17 PHE B CE2 1 ATOM 1625 C CZ . PHE B 2 17 ? 104.539 -6.289 3.802 1.00 44.07 ? 17 PHE B CZ 1 ATOM 1626 N N . PHE B 2 18 ? 110.996 -3.156 2.375 1.00 54.15 ? 18 PHE B N 1 ATOM 1627 C CA . PHE B 2 18 ? 112.165 -2.652 1.658 1.00 61.53 ? 18 PHE B CA 1 ATOM 1628 C C . PHE B 2 18 ? 112.698 -3.868 0.909 1.00 67.18 ? 18 PHE B C 1 ATOM 1629 O O . PHE B 2 18 ? 112.832 -4.940 1.500 1.00 69.95 ? 18 PHE B O 1 ATOM 1630 C CB . PHE B 2 18 ? 113.239 -2.164 2.626 1.00 62.76 ? 18 PHE B CB 1 ATOM 1631 C CG . PHE B 2 18 ? 112.774 -1.094 3.569 1.00 69.97 ? 18 PHE B CG 1 ATOM 1632 C CD1 . PHE B 2 18 ? 111.723 -1.325 4.450 1.00 70.54 ? 18 PHE B CD1 1 ATOM 1633 C CD2 . PHE B 2 18 ? 113.423 0.139 3.612 1.00 75.79 ? 18 PHE B CD2 1 ATOM 1634 C CE1 . PHE B 2 18 ? 111.327 -0.343 5.365 1.00 73.43 ? 18 PHE B CE1 1 ATOM 1635 C CE2 . PHE B 2 18 ? 113.035 1.135 4.527 1.00 76.38 ? 18 PHE B CE2 1 ATOM 1636 C CZ . PHE B 2 18 ? 111.987 0.890 5.404 1.00 75.20 ? 18 PHE B CZ 1 ATOM 1637 N N . ASN B 2 19 ? 113.008 -3.718 -0.377 1.00 71.65 ? 19 ASN B N 1 ATOM 1638 C CA . ASN B 2 19 ? 113.505 -4.849 -1.168 1.00 73.78 ? 19 ASN B CA 1 ATOM 1639 C C . ASN B 2 19 ? 112.466 -5.956 -1.094 1.00 72.40 ? 19 ASN B C 1 ATOM 1640 O O . ASN B 2 19 ? 112.707 -7.000 -0.492 1.00 71.28 ? 19 ASN B O 1 ATOM 1641 C CB . ASN B 2 19 ? 114.826 -5.392 -0.602 1.00 80.63 ? 19 ASN B CB 1 ATOM 1642 C CG . ASN B 2 19 ? 116.025 -4.516 -0.928 1.00 86.22 ? 19 ASN B CG 1 ATOM 1643 O OD1 . ASN B 2 19 ? 116.060 -3.332 -0.587 1.00 90.42 ? 19 ASN B OD1 1 ATOM 1644 N ND2 . ASN B 2 19 ? 117.027 -5.105 -1.582 1.00 88.66 ? 19 ASN B ND2 1 ATOM 1645 N N . GLY B 2 20 ? 111.308 -5.734 -1.696 1.00 71.82 ? 20 GLY B N 1 ATOM 1646 C CA . GLY B 2 20 ? 110.282 -6.753 -1.640 1.00 72.85 ? 20 GLY B CA 1 ATOM 1647 C C . GLY B 2 20 ? 109.987 -7.048 -0.186 1.00 72.44 ? 20 GLY B C 1 ATOM 1648 O O . GLY B 2 20 ? 109.509 -6.166 0.528 1.00 74.05 ? 20 GLY B O 1 ATOM 1649 N N . THR B 2 21 ? 110.283 -8.268 0.263 1.00 70.81 ? 21 THR B N 1 ATOM 1650 C CA . THR B 2 21 ? 110.033 -8.650 1.652 1.00 67.78 ? 21 THR B CA 1 ATOM 1651 C C . THR B 2 21 ? 111.335 -9.026 2.358 1.00 68.15 ? 21 THR B C 1 ATOM 1652 O O . THR B 2 21 ? 111.334 -9.650 3.417 1.00 66.68 ? 21 THR B O 1 ATOM 1653 C CB . THR B 2 21 ? 109.053 -9.835 1.728 1.00 63.81 ? 21 THR B CB 1 ATOM 1654 O OG1 . THR B 2 21 ? 109.711 -11.023 1.291 1.00 64.95 ? 21 THR B OG1 1 ATOM 1655 C CG2 . THR B 2 21 ? 107.858 -9.594 0.827 1.00 59.56 ? 21 THR B CG2 1 ATOM 1656 N N . GLU B 2 22 ? 112.442 -8.623 1.753 1.00 69.86 ? 22 GLU B N 1 ATOM 1657 C CA . GLU B 2 22 ? 113.779 -8.889 2.268 1.00 73.85 ? 22 GLU B CA 1 ATOM 1658 C C . GLU B 2 22 ? 114.048 -8.203 3.602 1.00 73.07 ? 22 GLU B C 1 ATOM 1659 O O . GLU B 2 22 ? 114.935 -8.608 4.351 1.00 75.78 ? 22 GLU B O 1 ATOM 1660 C CB . GLU B 2 22 ? 114.806 -8.424 1.234 1.00 79.81 ? 22 GLU B CB 1 ATOM 1661 C CG . GLU B 2 22 ? 116.251 -8.365 1.703 1.00 86.46 ? 22 GLU B CG 1 ATOM 1662 C CD . GLU B 2 22 ? 117.170 -7.779 0.636 1.00 92.91 ? 22 GLU B CD 1 ATOM 1663 O OE1 . GLU B 2 22 ? 117.297 -8.390 -0.451 1.00 94.55 ? 22 GLU B OE1 1 ATOM 1664 O OE2 . GLU B 2 22 ? 117.760 -6.702 0.882 1.00 96.58 ? 22 GLU B OE2 1 ATOM 1665 N N . ARG B 2 23 ? 113.287 -7.158 3.894 1.00 71.09 ? 23 ARG B N 1 ATOM 1666 C CA . ARG B 2 23 ? 113.460 -6.415 5.133 1.00 67.33 ? 23 ARG B CA 1 ATOM 1667 C C . ARG B 2 23 ? 112.126 -5.746 5.429 1.00 61.82 ? 23 ARG B C 1 ATOM 1668 O O . ARG B 2 23 ? 111.815 -4.701 4.873 1.00 62.55 ? 23 ARG B O 1 ATOM 1669 C CB . ARG B 2 23 ? 114.557 -5.365 4.949 1.00 71.73 ? 23 ARG B CB 1 ATOM 1670 C CG . ARG B 2 23 ? 115.204 -4.861 6.226 1.00 80.45 ? 23 ARG B CG 1 ATOM 1671 C CD . ARG B 2 23 ? 114.220 -4.157 7.138 1.00 90.80 ? 23 ARG B CD 1 ATOM 1672 N NE . ARG B 2 23 ? 114.901 -3.380 8.172 1.00 101.54 ? 23 ARG B NE 1 ATOM 1673 C CZ . ARG B 2 23 ? 114.294 -2.817 9.216 1.00 106.83 ? 23 ARG B CZ 1 ATOM 1674 N NH1 . ARG B 2 23 ? 112.980 -2.946 9.374 1.00 109.02 ? 23 ARG B NH1 1 ATOM 1675 N NH2 . ARG B 2 23 ? 114.998 -2.119 10.103 1.00 108.38 ? 23 ARG B NH2 1 ATOM 1676 N N . VAL B 2 24 ? 111.338 -6.362 6.299 1.00 55.76 ? 24 VAL B N 1 ATOM 1677 C CA . VAL B 2 24 ? 110.028 -5.843 6.661 1.00 50.56 ? 24 VAL B CA 1 ATOM 1678 C C . VAL B 2 24 ? 110.026 -5.180 8.035 1.00 49.49 ? 24 VAL B C 1 ATOM 1679 O O . VAL B 2 24 ? 110.767 -5.583 8.928 1.00 51.29 ? 24 VAL B O 1 ATOM 1680 C CB . VAL B 2 24 ? 108.990 -6.978 6.670 1.00 48.81 ? 24 VAL B CB 1 ATOM 1681 C CG1 . VAL B 2 24 ? 107.625 -6.450 7.054 1.00 49.75 ? 24 VAL B CG1 1 ATOM 1682 C CG2 . VAL B 2 24 ? 108.938 -7.627 5.315 1.00 47.30 ? 24 VAL B CG2 1 ATOM 1683 N N . ARG B 2 25 ? 109.190 -4.158 8.196 1.00 46.57 ? 25 ARG B N 1 ATOM 1684 C CA . ARG B 2 25 ? 109.064 -3.461 9.472 1.00 42.87 ? 25 ARG B CA 1 ATOM 1685 C C . ARG B 2 25 ? 107.588 -3.340 9.838 1.00 40.72 ? 25 ARG B C 1 ATOM 1686 O O . ARG B 2 25 ? 106.746 -3.093 8.977 1.00 42.70 ? 25 ARG B O 1 ATOM 1687 C CB . ARG B 2 25 ? 109.683 -2.077 9.398 1.00 39.16 ? 25 ARG B CB 1 ATOM 1688 C CG . ARG B 2 25 ? 109.829 -1.446 10.745 1.00 35.02 ? 25 ARG B CG 1 ATOM 1689 C CD . ARG B 2 25 ? 110.277 -0.039 10.587 1.00 39.38 ? 25 ARG B CD 1 ATOM 1690 N NE . ARG B 2 25 ? 110.631 0.547 11.865 1.00 45.51 ? 25 ARG B NE 1 ATOM 1691 C CZ . ARG B 2 25 ? 110.772 1.852 12.055 1.00 52.87 ? 25 ARG B CZ 1 ATOM 1692 N NH1 . ARG B 2 25 ? 110.577 2.692 11.041 1.00 55.81 ? 25 ARG B NH1 1 ATOM 1693 N NH2 . ARG B 2 25 ? 111.119 2.316 13.248 1.00 54.03 ? 25 ARG B NH2 1 ATOM 1694 N N . PHE B 2 26 ? 107.276 -3.510 11.116 1.00 37.30 ? 26 PHE B N 1 ATOM 1695 C CA . PHE B 2 26 ? 105.892 -3.456 11.575 1.00 33.20 ? 26 PHE B CA 1 ATOM 1696 C C . PHE B 2 26 ? 105.706 -2.374 12.629 1.00 32.39 ? 26 PHE B C 1 ATOM 1697 O O . PHE B 2 26 ? 106.555 -2.199 13.501 1.00 34.67 ? 26 PHE B O 1 ATOM 1698 C CB . PHE B 2 26 ? 105.503 -4.824 12.145 1.00 29.34 ? 26 PHE B CB 1 ATOM 1699 C CG . PHE B 2 26 ? 104.192 -4.837 12.863 1.00 25.49 ? 26 PHE B CG 1 ATOM 1700 C CD1 . PHE B 2 26 ? 103.000 -4.869 12.160 1.00 28.07 ? 26 PHE B CD1 1 ATOM 1701 C CD2 . PHE B 2 26 ? 104.149 -4.813 14.250 1.00 20.28 ? 26 PHE B CD2 1 ATOM 1702 C CE1 . PHE B 2 26 ? 101.779 -4.879 12.831 1.00 24.66 ? 26 PHE B CE1 1 ATOM 1703 C CE2 . PHE B 2 26 ? 102.941 -4.821 14.924 1.00 16.95 ? 26 PHE B CE2 1 ATOM 1704 C CZ . PHE B 2 26 ? 101.755 -4.854 14.213 1.00 20.34 ? 26 PHE B CZ 1 ATOM 1705 N N . LEU B 2 27 ? 104.602 -1.639 12.545 1.00 29.88 ? 27 LEU B N 1 ATOM 1706 C CA . LEU B 2 27 ? 104.324 -0.586 13.517 1.00 26.65 ? 27 LEU B CA 1 ATOM 1707 C C . LEU B 2 27 ? 102.872 -0.562 13.932 1.00 27.99 ? 27 LEU B C 1 ATOM 1708 O O . LEU B 2 27 ? 101.977 -0.876 13.144 1.00 29.16 ? 27 LEU B O 1 ATOM 1709 C CB . LEU B 2 27 ? 104.644 0.802 12.963 1.00 22.11 ? 27 LEU B CB 1 ATOM 1710 C CG . LEU B 2 27 ? 106.061 1.318 12.763 1.00 19.89 ? 27 LEU B CG 1 ATOM 1711 C CD1 . LEU B 2 27 ? 106.864 1.045 13.998 1.00 21.37 ? 27 LEU B CD1 1 ATOM 1712 C CD2 . LEU B 2 27 ? 106.687 0.659 11.583 1.00 21.74 ? 27 LEU B CD2 1 ATOM 1713 N N . HIS B 2 28 ? 102.651 -0.188 15.183 1.00 28.59 ? 28 HIS B N 1 ATOM 1714 C CA . HIS B 2 28 ? 101.306 -0.034 15.709 1.00 29.84 ? 28 HIS B CA 1 ATOM 1715 C C . HIS B 2 28 ? 101.270 1.355 16.330 1.00 32.74 ? 28 HIS B C 1 ATOM 1716 O O . HIS B 2 28 ? 102.041 1.669 17.247 1.00 33.14 ? 28 HIS B O 1 ATOM 1717 C CB . HIS B 2 28 ? 100.974 -1.055 16.783 1.00 30.09 ? 28 HIS B CB 1 ATOM 1718 C CG . HIS B 2 28 ? 99.614 -0.862 17.377 1.00 31.36 ? 28 HIS B CG 1 ATOM 1719 N ND1 . HIS B 2 28 ? 99.252 -1.375 18.603 1.00 34.13 ? 28 HIS B ND1 1 ATOM 1720 C CD2 . HIS B 2 28 ? 98.526 -0.207 16.909 1.00 31.11 ? 28 HIS B CD2 1 ATOM 1721 C CE1 . HIS B 2 28 ? 98.000 -1.043 18.864 1.00 33.68 ? 28 HIS B CE1 1 ATOM 1722 N NE2 . HIS B 2 28 ? 97.537 -0.335 17.851 1.00 29.67 ? 28 HIS B NE2 1 ATOM 1723 N N . ARG B 2 29 ? 100.385 2.195 15.816 1.00 32.95 ? 29 ARG B N 1 ATOM 1724 C CA . ARG B 2 29 ? 100.272 3.546 16.324 1.00 31.39 ? 29 ARG B CA 1 ATOM 1725 C C . ARG B 2 29 ? 98.900 3.733 16.926 1.00 30.94 ? 29 ARG B C 1 ATOM 1726 O O . ARG B 2 29 ? 97.891 3.594 16.235 1.00 31.20 ? 29 ARG B O 1 ATOM 1727 C CB . ARG B 2 29 ? 100.454 4.564 15.193 1.00 29.87 ? 29 ARG B CB 1 ATOM 1728 C CG . ARG B 2 29 ? 101.802 4.576 14.505 1.00 24.99 ? 29 ARG B CG 1 ATOM 1729 C CD . ARG B 2 29 ? 101.655 5.232 13.150 1.00 29.62 ? 29 ARG B CD 1 ATOM 1730 N NE . ARG B 2 29 ? 102.918 5.334 12.433 1.00 34.77 ? 29 ARG B NE 1 ATOM 1731 C CZ . ARG B 2 29 ? 103.923 6.115 12.811 1.00 37.90 ? 29 ARG B CZ 1 ATOM 1732 N NH1 . ARG B 2 29 ? 103.801 6.857 13.902 1.00 36.70 ? 29 ARG B NH1 1 ATOM 1733 N NH2 . ARG B 2 29 ? 105.043 6.162 12.095 1.00 37.42 ? 29 ARG B NH2 1 ATOM 1734 N N . ASP B 2 30 ? 98.853 4.012 18.218 1.00 30.31 ? 30 ASP B N 1 ATOM 1735 C CA . ASP B 2 30 ? 97.577 4.280 18.842 1.00 33.82 ? 30 ASP B CA 1 ATOM 1736 C C . ASP B 2 30 ? 97.541 5.792 18.798 1.00 33.67 ? 30 ASP B C 1 ATOM 1737 O O . ASP B 2 30 ? 98.484 6.446 19.225 1.00 33.81 ? 30 ASP B O 1 ATOM 1738 C CB . ASP B 2 30 ? 97.545 3.794 20.285 1.00 39.91 ? 30 ASP B CB 1 ATOM 1739 C CG . ASP B 2 30 ? 96.161 3.915 20.910 1.00 45.78 ? 30 ASP B CG 1 ATOM 1740 O OD1 . ASP B 2 30 ? 95.735 5.046 21.238 1.00 46.41 ? 30 ASP B OD1 1 ATOM 1741 O OD2 . ASP B 2 30 ? 95.493 2.869 21.063 1.00 51.74 ? 30 ASP B OD2 1 ATOM 1742 N N . ILE B 2 31 ? 96.475 6.356 18.254 1.00 35.51 ? 31 ILE B N 1 ATOM 1743 C CA . ILE B 2 31 ? 96.390 7.802 18.169 1.00 38.17 ? 31 ILE B CA 1 ATOM 1744 C C . ILE B 2 31 ? 95.140 8.395 18.786 1.00 40.42 ? 31 ILE B C 1 ATOM 1745 O O . ILE B 2 31 ? 94.029 7.874 18.631 1.00 40.80 ? 31 ILE B O 1 ATOM 1746 C CB . ILE B 2 31 ? 96.458 8.269 16.729 1.00 38.72 ? 31 ILE B CB 1 ATOM 1747 C CG1 . ILE B 2 31 ? 97.786 7.845 16.114 1.00 38.96 ? 31 ILE B CG1 1 ATOM 1748 C CG2 . ILE B 2 31 ? 96.317 9.771 16.678 1.00 38.35 ? 31 ILE B CG2 1 ATOM 1749 C CD1 . ILE B 2 31 ? 97.819 8.010 14.623 1.00 36.86 ? 31 ILE B CD1 1 ATOM 1750 N N . TYR B 2 32 ? 95.345 9.503 19.485 1.00 40.89 ? 32 TYR B N 1 ATOM 1751 C CA . TYR B 2 32 ? 94.261 10.210 20.128 1.00 41.46 ? 32 TYR B CA 1 ATOM 1752 C C . TYR B 2 32 ? 94.101 11.571 19.436 1.00 46.07 ? 32 TYR B C 1 ATOM 1753 O O . TYR B 2 32 ? 95.058 12.341 19.322 1.00 46.40 ? 32 TYR B O 1 ATOM 1754 C CB . TYR B 2 32 ? 94.566 10.390 21.610 1.00 32.48 ? 32 TYR B CB 1 ATOM 1755 C CG . TYR B 2 32 ? 93.392 10.928 22.347 1.00 26.96 ? 32 TYR B CG 1 ATOM 1756 C CD1 . TYR B 2 32 ? 92.189 10.252 22.328 1.00 32.45 ? 32 TYR B CD1 1 ATOM 1757 C CD2 . TYR B 2 32 ? 93.458 12.133 23.016 1.00 23.82 ? 32 TYR B CD2 1 ATOM 1758 C CE1 . TYR B 2 32 ? 91.069 10.764 22.954 1.00 35.64 ? 32 TYR B CE1 1 ATOM 1759 C CE2 . TYR B 2 32 ? 92.346 12.660 23.646 1.00 27.58 ? 32 TYR B CE2 1 ATOM 1760 C CZ . TYR B 2 32 ? 91.149 11.971 23.609 1.00 34.58 ? 32 TYR B CZ 1 ATOM 1761 O OH . TYR B 2 32 ? 90.016 12.488 24.198 1.00 41.57 ? 32 TYR B OH 1 ATOM 1762 N N . ASN B 2 33 ? 92.888 11.851 18.964 1.00 49.28 ? 33 ASN B N 1 ATOM 1763 C CA . ASN B 2 33 ? 92.588 13.099 18.264 1.00 48.22 ? 33 ASN B CA 1 ATOM 1764 C C . ASN B 2 33 ? 93.556 13.345 17.117 1.00 46.27 ? 33 ASN B C 1 ATOM 1765 O O . ASN B 2 33 ? 93.242 13.063 15.958 1.00 49.37 ? 33 ASN B O 1 ATOM 1766 C CB . ASN B 2 33 ? 92.605 14.289 19.233 1.00 49.98 ? 33 ASN B CB 1 ATOM 1767 C CG . ASN B 2 33 ? 91.450 14.247 20.234 1.00 51.59 ? 33 ASN B CG 1 ATOM 1768 O OD1 . ASN B 2 33 ? 90.306 13.988 19.867 1.00 54.69 ? 33 ASN B OD1 1 ATOM 1769 N ND2 . ASN B 2 33 ? 91.747 14.512 21.499 1.00 50.66 ? 33 ASN B ND2 1 ATOM 1770 N N . GLN B 2 34 ? 94.736 13.862 17.423 1.00 42.24 ? 34 GLN B N 1 ATOM 1771 C CA . GLN B 2 34 ? 95.684 14.117 16.365 1.00 42.73 ? 34 GLN B CA 1 ATOM 1772 C C . GLN B 2 34 ? 97.117 13.903 16.798 1.00 44.34 ? 34 GLN B C 1 ATOM 1773 O O . GLN B 2 34 ? 98.032 14.305 16.101 1.00 47.11 ? 34 GLN B O 1 ATOM 1774 C CB . GLN B 2 34 ? 95.495 15.537 15.846 1.00 44.96 ? 34 GLN B CB 1 ATOM 1775 C CG . GLN B 2 34 ? 96.289 15.870 14.594 1.00 50.14 ? 34 GLN B CG 1 ATOM 1776 C CD . GLN B 2 34 ? 96.005 17.275 14.061 1.00 55.62 ? 34 GLN B CD 1 ATOM 1777 O OE1 . GLN B 2 34 ? 96.570 17.686 13.041 1.00 57.32 ? 34 GLN B OE1 1 ATOM 1778 N NE2 . GLN B 2 34 ? 95.127 18.015 14.748 1.00 53.03 ? 34 GLN B NE2 1 ATOM 1779 N N . GLU B 2 35 ? 97.324 13.271 17.946 1.00 47.84 ? 35 GLU B N 1 ATOM 1780 C CA . GLU B 2 35 ? 98.682 13.012 18.424 1.00 49.50 ? 35 GLU B CA 1 ATOM 1781 C C . GLU B 2 35 ? 98.905 11.521 18.685 1.00 49.81 ? 35 GLU B C 1 ATOM 1782 O O . GLU B 2 35 ? 98.015 10.817 19.169 1.00 48.21 ? 35 GLU B O 1 ATOM 1783 C CB . GLU B 2 35 ? 98.970 13.802 19.710 1.00 55.09 ? 35 GLU B CB 1 ATOM 1784 C CG . GLU B 2 35 ? 98.055 13.451 20.894 1.00 64.00 ? 35 GLU B CG 1 ATOM 1785 C CD . GLU B 2 35 ? 98.552 13.998 22.236 1.00 69.59 ? 35 GLU B CD 1 ATOM 1786 O OE1 . GLU B 2 35 ? 98.826 15.220 22.332 1.00 73.51 ? 35 GLU B OE1 1 ATOM 1787 O OE2 . GLU B 2 35 ? 98.658 13.201 23.198 1.00 68.44 ? 35 GLU B OE2 1 ATOM 1788 N N . GLU B 2 36 ? 100.094 11.035 18.346 1.00 48.74 ? 36 GLU B N 1 ATOM 1789 C CA . GLU B 2 36 ? 100.423 9.638 18.576 1.00 46.75 ? 36 GLU B CA 1 ATOM 1790 C C . GLU B 2 36 ? 100.939 9.518 20.011 1.00 47.76 ? 36 GLU B C 1 ATOM 1791 O O . GLU B 2 36 ? 101.896 10.197 20.390 1.00 49.02 ? 36 GLU B O 1 ATOM 1792 C CB . GLU B 2 36 ? 101.495 9.179 17.589 1.00 45.58 ? 36 GLU B CB 1 ATOM 1793 C CG . GLU B 2 36 ? 102.023 7.764 17.841 1.00 43.91 ? 36 GLU B CG 1 ATOM 1794 C CD . GLU B 2 36 ? 103.173 7.390 16.921 1.00 40.48 ? 36 GLU B CD 1 ATOM 1795 O OE1 . GLU B 2 36 ? 104.227 8.055 16.979 1.00 37.97 ? 36 GLU B OE1 1 ATOM 1796 O OE2 . GLU B 2 36 ? 103.018 6.431 16.137 1.00 37.23 ? 36 GLU B OE2 1 ATOM 1797 N N . ASP B 2 37 ? 100.302 8.660 20.806 1.00 47.14 ? 37 ASP B N 1 ATOM 1798 C CA . ASP B 2 37 ? 100.688 8.460 22.201 1.00 44.75 ? 37 ASP B CA 1 ATOM 1799 C C . ASP B 2 37 ? 101.334 7.109 22.473 1.00 41.30 ? 37 ASP B C 1 ATOM 1800 O O . ASP B 2 37 ? 102.262 7.008 23.260 1.00 40.17 ? 37 ASP B O 1 ATOM 1801 C CB . ASP B 2 37 ? 99.469 8.615 23.100 1.00 49.32 ? 37 ASP B CB 1 ATOM 1802 C CG . ASP B 2 37 ? 98.283 7.831 22.597 1.00 54.60 ? 37 ASP B CG 1 ATOM 1803 O OD1 . ASP B 2 37 ? 97.760 8.200 21.530 1.00 61.49 ? 37 ASP B OD1 1 ATOM 1804 O OD2 . ASP B 2 37 ? 97.873 6.849 23.254 1.00 58.00 ? 37 ASP B OD2 1 ATOM 1805 N N . LEU B 2 38 ? 100.836 6.066 21.832 1.00 39.85 ? 38 LEU B N 1 ATOM 1806 C CA . LEU B 2 38 ? 101.392 4.735 22.032 1.00 41.08 ? 38 LEU B CA 1 ATOM 1807 C C . LEU B 2 38 ? 101.927 4.201 20.713 1.00 42.61 ? 38 LEU B C 1 ATOM 1808 O O . LEU B 2 38 ? 101.322 4.419 19.664 1.00 45.77 ? 38 LEU B O 1 ATOM 1809 C CB . LEU B 2 38 ? 100.311 3.807 22.572 1.00 39.18 ? 38 LEU B CB 1 ATOM 1810 C CG . LEU B 2 38 ? 100.748 2.394 22.923 1.00 35.34 ? 38 LEU B CG 1 ATOM 1811 C CD1 . LEU B 2 38 ? 101.894 2.440 23.909 1.00 36.24 ? 38 LEU B CD1 1 ATOM 1812 C CD2 . LEU B 2 38 ? 99.568 1.652 23.506 1.00 37.01 ? 38 LEU B CD2 1 ATOM 1813 N N . ARG B 2 39 ? 103.047 3.490 20.749 1.00 41.90 ? 39 ARG B N 1 ATOM 1814 C CA . ARG B 2 39 ? 103.606 2.988 19.503 1.00 43.49 ? 39 ARG B CA 1 ATOM 1815 C C . ARG B 2 39 ? 104.498 1.765 19.609 1.00 43.65 ? 39 ARG B C 1 ATOM 1816 O O . ARG B 2 39 ? 105.475 1.771 20.354 1.00 44.16 ? 39 ARG B O 1 ATOM 1817 C CB . ARG B 2 39 ? 104.400 4.100 18.822 1.00 44.99 ? 39 ARG B CB 1 ATOM 1818 C CG . ARG B 2 39 ? 105.058 3.672 17.524 1.00 48.12 ? 39 ARG B CG 1 ATOM 1819 C CD . ARG B 2 39 ? 106.552 3.923 17.555 1.00 50.14 ? 39 ARG B CD 1 ATOM 1820 N NE . ARG B 2 39 ? 106.877 5.329 17.783 1.00 51.82 ? 39 ARG B NE 1 ATOM 1821 C CZ . ARG B 2 39 ? 106.589 6.315 16.939 1.00 52.51 ? 39 ARG B CZ 1 ATOM 1822 N NH1 . ARG B 2 39 ? 105.962 6.064 15.799 1.00 53.78 ? 39 ARG B NH1 1 ATOM 1823 N NH2 . ARG B 2 39 ? 106.941 7.557 17.230 1.00 54.28 ? 39 ARG B NH2 1 ATOM 1824 N N . PHE B 2 40 ? 104.171 0.719 18.853 1.00 42.64 ? 40 PHE B N 1 ATOM 1825 C CA . PHE B 2 40 ? 104.995 -0.479 18.852 1.00 40.42 ? 40 PHE B CA 1 ATOM 1826 C C . PHE B 2 40 ? 105.799 -0.504 17.579 1.00 38.60 ? 40 PHE B C 1 ATOM 1827 O O . PHE B 2 40 ? 105.247 -0.430 16.487 1.00 35.56 ? 40 PHE B O 1 ATOM 1828 C CB . PHE B 2 40 ? 104.162 -1.762 18.934 1.00 43.90 ? 40 PHE B CB 1 ATOM 1829 C CG . PHE B 2 40 ? 104.984 -3.028 18.766 1.00 45.20 ? 40 PHE B CG 1 ATOM 1830 C CD1 . PHE B 2 40 ? 105.427 -3.433 17.508 1.00 45.29 ? 40 PHE B CD1 1 ATOM 1831 C CD2 . PHE B 2 40 ? 105.356 -3.784 19.870 1.00 44.89 ? 40 PHE B CD2 1 ATOM 1832 C CE1 . PHE B 2 40 ? 106.226 -4.560 17.355 1.00 41.99 ? 40 PHE B CE1 1 ATOM 1833 C CE2 . PHE B 2 40 ? 106.156 -4.913 19.722 1.00 45.08 ? 40 PHE B CE2 1 ATOM 1834 C CZ . PHE B 2 40 ? 106.591 -5.299 18.463 1.00 43.53 ? 40 PHE B CZ 1 ATOM 1835 N N . ASP B 2 41 ? 107.109 -0.617 17.730 1.00 41.38 ? 41 ASP B N 1 ATOM 1836 C CA . ASP B 2 41 ? 108.012 -0.669 16.593 1.00 47.20 ? 41 ASP B CA 1 ATOM 1837 C C . ASP B 2 41 ? 108.623 -2.071 16.516 1.00 49.88 ? 41 ASP B C 1 ATOM 1838 O O . ASP B 2 41 ? 109.194 -2.557 17.491 1.00 52.98 ? 41 ASP B O 1 ATOM 1839 C CB . ASP B 2 41 ? 109.118 0.366 16.771 1.00 48.26 ? 41 ASP B CB 1 ATOM 1840 C CG . ASP B 2 41 ? 109.734 0.790 15.457 1.00 52.00 ? 41 ASP B CG 1 ATOM 1841 O OD1 . ASP B 2 41 ? 110.059 -0.088 14.626 1.00 49.21 ? 41 ASP B OD1 1 ATOM 1842 O OD2 . ASP B 2 41 ? 109.894 2.013 15.262 1.00 54.12 ? 41 ASP B OD2 1 ATOM 1843 N N . SER B 2 42 ? 108.502 -2.725 15.364 1.00 50.67 ? 42 SER B N 1 ATOM 1844 C CA . SER B 2 42 ? 109.052 -4.067 15.206 1.00 48.16 ? 42 SER B CA 1 ATOM 1845 C C . SER B 2 42 ? 110.545 -4.039 15.440 1.00 48.84 ? 42 SER B C 1 ATOM 1846 O O . SER B 2 42 ? 111.130 -5.051 15.789 1.00 50.27 ? 42 SER B O 1 ATOM 1847 C CB . SER B 2 42 ? 108.772 -4.622 13.803 1.00 47.38 ? 42 SER B CB 1 ATOM 1848 O OG . SER B 2 42 ? 109.511 -3.943 12.802 1.00 44.64 ? 42 SER B OG 1 ATOM 1849 N N . ASP B 2 43 ? 111.157 -2.875 15.254 1.00 50.10 ? 43 ASP B N 1 ATOM 1850 C CA . ASP B 2 43 ? 112.592 -2.733 15.440 1.00 53.10 ? 43 ASP B CA 1 ATOM 1851 C C . ASP B 2 43 ? 112.993 -2.439 16.875 1.00 54.79 ? 43 ASP B C 1 ATOM 1852 O O . ASP B 2 43 ? 114.177 -2.370 17.179 1.00 59.91 ? 43 ASP B O 1 ATOM 1853 C CB . ASP B 2 43 ? 113.150 -1.627 14.544 1.00 56.35 ? 43 ASP B CB 1 ATOM 1854 C CG . ASP B 2 43 ? 113.098 -1.982 13.078 1.00 61.67 ? 43 ASP B CG 1 ATOM 1855 O OD1 . ASP B 2 43 ? 112.878 -3.175 12.770 1.00 62.93 ? 43 ASP B OD1 1 ATOM 1856 O OD2 . ASP B 2 43 ? 113.289 -1.069 12.237 1.00 63.49 ? 43 ASP B OD2 1 ATOM 1857 N N . VAL B 2 44 ? 112.028 -2.254 17.764 1.00 54.46 ? 44 VAL B N 1 ATOM 1858 C CA . VAL B 2 44 ? 112.364 -1.970 19.155 1.00 52.84 ? 44 VAL B CA 1 ATOM 1859 C C . VAL B 2 44 ? 111.997 -3.146 20.044 1.00 53.86 ? 44 VAL B C 1 ATOM 1860 O O . VAL B 2 44 ? 112.603 -3.346 21.087 1.00 55.69 ? 44 VAL B O 1 ATOM 1861 C CB . VAL B 2 44 ? 111.638 -0.709 19.665 1.00 52.15 ? 44 VAL B CB 1 ATOM 1862 C CG1 . VAL B 2 44 ? 112.088 -0.381 21.079 1.00 50.70 ? 44 VAL B CG1 1 ATOM 1863 C CG2 . VAL B 2 44 ? 111.915 0.454 18.736 1.00 50.73 ? 44 VAL B CG2 1 ATOM 1864 N N . GLY B 2 45 ? 110.999 -3.920 19.626 1.00 54.53 ? 45 GLY B N 1 ATOM 1865 C CA . GLY B 2 45 ? 110.580 -5.072 20.402 1.00 53.35 ? 45 GLY B CA 1 ATOM 1866 C C . GLY B 2 45 ? 109.424 -4.809 21.347 1.00 53.48 ? 45 GLY B C 1 ATOM 1867 O O . GLY B 2 45 ? 108.482 -5.593 21.421 1.00 55.74 ? 45 GLY B O 1 ATOM 1868 N N . GLU B 2 46 ? 109.487 -3.697 22.065 1.00 53.06 ? 46 GLU B N 1 ATOM 1869 C CA . GLU B 2 46 ? 108.448 -3.351 23.024 1.00 55.29 ? 46 GLU B CA 1 ATOM 1870 C C . GLU B 2 46 ? 107.659 -2.102 22.643 1.00 55.01 ? 46 GLU B C 1 ATOM 1871 O O . GLU B 2 46 ? 107.937 -1.457 21.633 1.00 54.85 ? 46 GLU B O 1 ATOM 1872 C CB . GLU B 2 46 ? 109.083 -3.123 24.381 1.00 56.30 ? 46 GLU B CB 1 ATOM 1873 C CG . GLU B 2 46 ? 110.079 -1.996 24.344 1.00 60.89 ? 46 GLU B CG 1 ATOM 1874 C CD . GLU B 2 46 ? 110.745 -1.777 25.669 1.00 66.80 ? 46 GLU B CD 1 ATOM 1875 O OE1 . GLU B 2 46 ? 111.373 -2.732 26.173 1.00 72.22 ? 46 GLU B OE1 1 ATOM 1876 O OE2 . GLU B 2 46 ? 110.642 -0.655 26.210 1.00 68.05 ? 46 GLU B OE2 1 ATOM 1877 N N . TYR B 2 47 ? 106.675 -1.765 23.472 1.00 53.93 ? 47 TYR B N 1 ATOM 1878 C CA . TYR B 2 47 ? 105.854 -0.590 23.244 1.00 50.55 ? 47 TYR B CA 1 ATOM 1879 C C . TYR B 2 47 ? 106.545 0.594 23.874 1.00 51.46 ? 47 TYR B C 1 ATOM 1880 O O . TYR B 2 47 ? 107.265 0.442 24.858 1.00 51.02 ? 47 TYR B O 1 ATOM 1881 C CB . TYR B 2 47 ? 104.472 -0.746 23.885 1.00 46.93 ? 47 TYR B CB 1 ATOM 1882 C CG . TYR B 2 47 ? 103.429 -1.373 22.994 1.00 45.99 ? 47 TYR B CG 1 ATOM 1883 C CD1 . TYR B 2 47 ? 103.389 -2.745 22.787 1.00 46.99 ? 47 TYR B CD1 1 ATOM 1884 C CD2 . TYR B 2 47 ? 102.492 -0.587 22.337 1.00 46.70 ? 47 TYR B CD2 1 ATOM 1885 C CE1 . TYR B 2 47 ? 102.440 -3.319 21.945 1.00 46.72 ? 47 TYR B CE1 1 ATOM 1886 C CE2 . TYR B 2 47 ? 101.543 -1.150 21.491 1.00 46.87 ? 47 TYR B CE2 1 ATOM 1887 C CZ . TYR B 2 47 ? 101.522 -2.515 21.301 1.00 46.39 ? 47 TYR B CZ 1 ATOM 1888 O OH . TYR B 2 47 ? 100.589 -3.080 20.463 1.00 47.52 ? 47 TYR B OH 1 ATOM 1889 N N . ARG B 2 48 ? 106.333 1.767 23.287 1.00 54.86 ? 48 ARG B N 1 ATOM 1890 C CA . ARG B 2 48 ? 106.885 3.026 23.791 1.00 57.29 ? 48 ARG B CA 1 ATOM 1891 C C . ARG B 2 48 ? 105.724 4.011 23.860 1.00 54.13 ? 48 ARG B C 1 ATOM 1892 O O . ARG B 2 48 ? 104.868 4.044 22.971 1.00 53.36 ? 48 ARG B O 1 ATOM 1893 C CB . ARG B 2 48 ? 107.948 3.605 22.849 1.00 63.73 ? 48 ARG B CB 1 ATOM 1894 C CG . ARG B 2 48 ? 109.168 2.744 22.625 1.00 77.35 ? 48 ARG B CG 1 ATOM 1895 C CD . ARG B 2 48 ? 110.008 2.592 23.879 1.00 88.77 ? 48 ARG B CD 1 ATOM 1896 N NE . ARG B 2 48 ? 111.229 1.838 23.598 1.00 101.33 ? 48 ARG B NE 1 ATOM 1897 C CZ . ARG B 2 48 ? 112.072 1.400 24.527 1.00 107.51 ? 48 ARG B CZ 1 ATOM 1898 N NH1 . ARG B 2 48 ? 111.829 1.640 25.811 1.00 111.34 ? 48 ARG B NH1 1 ATOM 1899 N NH2 . ARG B 2 48 ? 113.154 0.715 24.174 1.00 109.90 ? 48 ARG B NH2 1 ATOM 1900 N N . ALA B 2 49 ? 105.683 4.807 24.918 1.00 51.56 ? 49 ALA B N 1 ATOM 1901 C CA . ALA B 2 49 ? 104.628 5.794 25.064 1.00 49.07 ? 49 ALA B CA 1 ATOM 1902 C C . ALA B 2 49 ? 105.205 7.135 24.640 1.00 47.21 ? 49 ALA B C 1 ATOM 1903 O O . ALA B 2 49 ? 106.053 7.692 25.332 1.00 47.83 ? 49 ALA B O 1 ATOM 1904 C CB . ALA B 2 49 ? 104.155 5.852 26.511 1.00 46.85 ? 49 ALA B CB 1 ATOM 1905 N N . VAL B 2 50 ? 104.758 7.644 23.495 1.00 45.49 ? 50 VAL B N 1 ATOM 1906 C CA . VAL B 2 50 ? 105.241 8.925 22.990 1.00 43.69 ? 50 VAL B CA 1 ATOM 1907 C C . VAL B 2 50 ? 104.859 10.041 23.966 1.00 45.59 ? 50 VAL B C 1 ATOM 1908 O O . VAL B 2 50 ? 105.718 10.761 24.479 1.00 50.01 ? 50 VAL B O 1 ATOM 1909 C CB . VAL B 2 50 ? 104.651 9.232 21.600 1.00 38.54 ? 50 VAL B CB 1 ATOM 1910 C CG1 . VAL B 2 50 ? 105.389 10.398 20.970 1.00 39.46 ? 50 VAL B CG1 1 ATOM 1911 C CG2 . VAL B 2 50 ? 104.754 8.009 20.712 1.00 36.20 ? 50 VAL B CG2 1 ATOM 1912 N N . THR B 2 51 ? 103.566 10.171 24.231 1.00 45.37 ? 51 THR B N 1 ATOM 1913 C CA . THR B 2 51 ? 103.076 11.180 25.155 1.00 44.20 ? 51 THR B CA 1 ATOM 1914 C C . THR B 2 51 ? 102.582 10.510 26.429 1.00 44.67 ? 51 THR B C 1 ATOM 1915 O O . THR B 2 51 ? 102.205 9.343 26.427 1.00 43.04 ? 51 THR B O 1 ATOM 1916 C CB . THR B 2 51 ? 101.907 11.957 24.544 1.00 44.82 ? 51 THR B CB 1 ATOM 1917 O OG1 . THR B 2 51 ? 100.741 11.119 24.501 1.00 43.73 ? 51 THR B OG1 1 ATOM 1918 C CG2 . THR B 2 51 ? 102.257 12.396 23.138 1.00 43.28 ? 51 THR B CG2 1 ATOM 1919 N N . GLU B 2 52 ? 102.577 11.252 27.522 1.00 47.09 ? 52 GLU B N 1 ATOM 1920 C CA . GLU B 2 52 ? 102.106 10.710 28.785 1.00 53.23 ? 52 GLU B CA 1 ATOM 1921 C C . GLU B 2 52 ? 100.748 10.017 28.713 1.00 51.65 ? 52 GLU B C 1 ATOM 1922 O O . GLU B 2 52 ? 100.373 9.265 29.608 1.00 50.95 ? 52 GLU B O 1 ATOM 1923 C CB . GLU B 2 52 ? 102.036 11.825 29.823 1.00 63.34 ? 52 GLU B CB 1 ATOM 1924 C CG . GLU B 2 52 ? 103.380 12.154 30.408 1.00 72.97 ? 52 GLU B CG 1 ATOM 1925 C CD . GLU B 2 52 ? 104.111 10.894 30.796 1.00 77.63 ? 52 GLU B CD 1 ATOM 1926 O OE1 . GLU B 2 52 ? 104.610 10.204 29.877 1.00 79.33 ? 52 GLU B OE1 1 ATOM 1927 O OE2 . GLU B 2 52 ? 104.160 10.584 32.009 1.00 78.60 ? 52 GLU B OE2 1 ATOM 1928 N N . LEU B 2 53 ? 100.009 10.268 27.645 1.00 50.33 ? 53 LEU B N 1 ATOM 1929 C CA . LEU B 2 53 ? 98.691 9.683 27.504 1.00 45.85 ? 53 LEU B CA 1 ATOM 1930 C C . LEU B 2 53 ? 98.742 8.168 27.341 1.00 46.57 ? 53 LEU B C 1 ATOM 1931 O O . LEU B 2 53 ? 97.792 7.471 27.686 1.00 45.38 ? 53 LEU B O 1 ATOM 1932 C CB . LEU B 2 53 ? 97.978 10.318 26.311 1.00 39.79 ? 53 LEU B CB 1 ATOM 1933 C CG . LEU B 2 53 ? 96.454 10.272 26.375 1.00 34.92 ? 53 LEU B CG 1 ATOM 1934 C CD1 . LEU B 2 53 ? 95.991 11.057 27.569 1.00 25.43 ? 53 LEU B CD1 1 ATOM 1935 C CD2 . LEU B 2 53 ? 95.855 10.843 25.105 1.00 37.69 ? 53 LEU B CD2 1 ATOM 1936 N N . GLY B 2 54 ? 99.855 7.661 26.822 1.00 48.56 ? 54 GLY B N 1 ATOM 1937 C CA . GLY B 2 54 ? 99.980 6.229 26.612 1.00 53.49 ? 54 GLY B CA 1 ATOM 1938 C C . GLY B 2 54 ? 100.696 5.480 27.723 1.00 58.32 ? 54 GLY B C 1 ATOM 1939 O O . GLY B 2 54 ? 100.581 4.256 27.828 1.00 59.10 ? 54 GLY B O 1 ATOM 1940 N N . ARG B 2 55 ? 101.430 6.221 28.552 1.00 60.80 ? 55 ARG B N 1 ATOM 1941 C CA . ARG B 2 55 ? 102.196 5.666 29.670 1.00 56.64 ? 55 ARG B CA 1 ATOM 1942 C C . ARG B 2 55 ? 101.662 4.352 30.227 1.00 51.90 ? 55 ARG B C 1 ATOM 1943 O O . ARG B 2 55 ? 102.325 3.331 30.142 1.00 51.50 ? 55 ARG B O 1 ATOM 1944 C CB . ARG B 2 55 ? 102.292 6.695 30.795 1.00 61.89 ? 55 ARG B CB 1 ATOM 1945 C CG . ARG B 2 55 ? 102.987 6.190 32.040 1.00 71.73 ? 55 ARG B CG 1 ATOM 1946 C CD . ARG B 2 55 ? 104.309 6.894 32.238 1.00 80.25 ? 55 ARG B CD 1 ATOM 1947 N NE . ARG B 2 55 ? 105.106 6.854 31.018 1.00 89.83 ? 55 ARG B NE 1 ATOM 1948 C CZ . ARG B 2 55 ? 106.345 7.322 30.923 1.00 93.85 ? 55 ARG B CZ 1 ATOM 1949 N NH1 . ARG B 2 55 ? 106.929 7.864 31.988 1.00 94.94 ? 55 ARG B NH1 1 ATOM 1950 N NH2 . ARG B 2 55 ? 106.996 7.252 29.765 1.00 94.21 ? 55 ARG B NH2 1 ATOM 1951 N N . PRO B 2 56 ? 100.453 4.356 30.797 1.00 48.64 ? 56 PRO B N 1 ATOM 1952 C CA . PRO B 2 56 ? 99.890 3.125 31.352 1.00 49.31 ? 56 PRO B CA 1 ATOM 1953 C C . PRO B 2 56 ? 99.981 1.941 30.403 1.00 49.77 ? 56 PRO B C 1 ATOM 1954 O O . PRO B 2 56 ? 100.646 0.949 30.687 1.00 50.08 ? 56 PRO B O 1 ATOM 1955 C CB . PRO B 2 56 ? 98.444 3.508 31.641 1.00 48.86 ? 56 PRO B CB 1 ATOM 1956 C CG . PRO B 2 56 ? 98.545 4.946 31.962 1.00 50.80 ? 56 PRO B CG 1 ATOM 1957 C CD . PRO B 2 56 ? 99.478 5.452 30.894 1.00 50.66 ? 56 PRO B CD 1 ATOM 1958 N N . ASP B 2 57 ? 99.304 2.048 29.271 1.00 50.37 ? 57 ASP B N 1 ATOM 1959 C CA . ASP B 2 57 ? 99.307 0.979 28.293 1.00 51.09 ? 57 ASP B CA 1 ATOM 1960 C C . ASP B 2 57 ? 100.692 0.365 28.091 1.00 51.46 ? 57 ASP B C 1 ATOM 1961 O O . ASP B 2 57 ? 100.903 -0.820 28.352 1.00 50.82 ? 57 ASP B O 1 ATOM 1962 C CB . ASP B 2 57 ? 98.749 1.506 26.975 1.00 51.25 ? 57 ASP B CB 1 ATOM 1963 C CG . ASP B 2 57 ? 97.255 1.754 27.044 1.00 55.70 ? 57 ASP B CG 1 ATOM 1964 O OD1 . ASP B 2 57 ? 96.746 1.995 28.162 1.00 56.08 ? 57 ASP B OD1 1 ATOM 1965 O OD2 . ASP B 2 57 ? 96.592 1.715 25.983 1.00 59.99 ? 57 ASP B OD2 1 ATOM 1966 N N . ALA B 2 58 ? 101.640 1.178 27.647 1.00 52.22 ? 58 ALA B N 1 ATOM 1967 C CA . ALA B 2 58 ? 102.991 0.698 27.403 1.00 51.29 ? 58 ALA B CA 1 ATOM 1968 C C . ALA B 2 58 ? 103.498 -0.227 28.500 1.00 51.25 ? 58 ALA B C 1 ATOM 1969 O O . ALA B 2 58 ? 103.803 -1.392 28.254 1.00 51.59 ? 58 ALA B O 1 ATOM 1970 C CB . ALA B 2 58 ? 103.931 1.877 27.240 1.00 50.45 ? 58 ALA B CB 1 ATOM 1971 N N . GLU B 2 59 ? 103.573 0.290 29.718 1.00 52.76 ? 59 GLU B N 1 ATOM 1972 C CA . GLU B 2 59 ? 104.074 -0.490 30.836 1.00 54.07 ? 59 GLU B CA 1 ATOM 1973 C C . GLU B 2 59 ? 103.259 -1.725 31.132 1.00 51.36 ? 59 GLU B C 1 ATOM 1974 O O . GLU B 2 59 ? 103.775 -2.678 31.697 1.00 53.33 ? 59 GLU B O 1 ATOM 1975 C CB . GLU B 2 59 ? 104.184 0.391 32.079 1.00 59.34 ? 59 GLU B CB 1 ATOM 1976 C CG . GLU B 2 59 ? 105.264 1.455 31.929 1.00 70.67 ? 59 GLU B CG 1 ATOM 1977 C CD . GLU B 2 59 ? 105.050 2.659 32.827 1.00 78.06 ? 59 GLU B CD 1 ATOM 1978 O OE1 . GLU B 2 59 ? 105.708 3.699 32.581 1.00 80.45 ? 59 GLU B OE1 1 ATOM 1979 O OE2 . GLU B 2 59 ? 104.231 2.566 33.771 1.00 80.16 ? 59 GLU B OE2 1 ATOM 1980 N N . TYR B 2 60 ? 101.990 -1.728 30.751 1.00 48.64 ? 60 TYR B N 1 ATOM 1981 C CA . TYR B 2 60 ? 101.179 -2.903 31.005 1.00 47.35 ? 60 TYR B CA 1 ATOM 1982 C C . TYR B 2 60 ? 101.427 -4.001 29.981 1.00 49.20 ? 60 TYR B C 1 ATOM 1983 O O . TYR B 2 60 ? 101.364 -5.184 30.306 1.00 52.00 ? 60 TYR B O 1 ATOM 1984 C CB . TYR B 2 60 ? 99.706 -2.566 30.983 1.00 45.29 ? 60 TYR B CB 1 ATOM 1985 C CG . TYR B 2 60 ? 98.845 -3.809 30.949 1.00 48.31 ? 60 TYR B CG 1 ATOM 1986 C CD1 . TYR B 2 60 ? 98.578 -4.534 32.108 1.00 48.38 ? 60 TYR B CD1 1 ATOM 1987 C CD2 . TYR B 2 60 ? 98.283 -4.255 29.757 1.00 51.72 ? 60 TYR B CD2 1 ATOM 1988 C CE1 . TYR B 2 60 ? 97.760 -5.669 32.080 1.00 47.52 ? 60 TYR B CE1 1 ATOM 1989 C CE2 . TYR B 2 60 ? 97.470 -5.388 29.719 1.00 51.63 ? 60 TYR B CE2 1 ATOM 1990 C CZ . TYR B 2 60 ? 97.209 -6.085 30.883 1.00 48.31 ? 60 TYR B CZ 1 ATOM 1991 O OH . TYR B 2 60 ? 96.371 -7.175 30.840 1.00 48.22 ? 60 TYR B OH 1 ATOM 1992 N N . TRP B 2 61 ? 101.679 -3.616 28.736 1.00 48.79 ? 61 TRP B N 1 ATOM 1993 C CA . TRP B 2 61 ? 101.921 -4.603 27.693 1.00 44.66 ? 61 TRP B CA 1 ATOM 1994 C C . TRP B 2 61 ? 103.354 -5.083 27.748 1.00 44.01 ? 61 TRP B C 1 ATOM 1995 O O . TRP B 2 61 ? 103.618 -6.268 27.584 1.00 47.36 ? 61 TRP B O 1 ATOM 1996 C CB . TRP B 2 61 ? 101.624 -4.014 26.312 1.00 42.27 ? 61 TRP B CB 1 ATOM 1997 C CG . TRP B 2 61 ? 100.181 -3.770 26.094 1.00 36.03 ? 61 TRP B CG 1 ATOM 1998 C CD1 . TRP B 2 61 ? 99.571 -2.572 25.892 1.00 36.81 ? 61 TRP B CD1 1 ATOM 1999 C CD2 . TRP B 2 61 ? 99.149 -4.750 26.103 1.00 32.62 ? 61 TRP B CD2 1 ATOM 2000 N NE1 . TRP B 2 61 ? 98.212 -2.742 25.776 1.00 32.83 ? 61 TRP B NE1 1 ATOM 2001 C CE2 . TRP B 2 61 ? 97.928 -4.073 25.904 1.00 32.06 ? 61 TRP B CE2 1 ATOM 2002 C CE3 . TRP B 2 61 ? 99.136 -6.137 26.259 1.00 31.96 ? 61 TRP B CE3 1 ATOM 2003 C CZ2 . TRP B 2 61 ? 96.706 -4.735 25.859 1.00 31.57 ? 61 TRP B CZ2 1 ATOM 2004 C CZ3 . TRP B 2 61 ? 97.920 -6.797 26.212 1.00 33.20 ? 61 TRP B CZ3 1 ATOM 2005 C CH2 . TRP B 2 61 ? 96.720 -6.094 26.015 1.00 32.60 ? 61 TRP B CH2 1 ATOM 2006 N N . ASN B 2 62 ? 104.277 -4.163 27.990 1.00 41.23 ? 62 ASN B N 1 ATOM 2007 C CA . ASN B 2 62 ? 105.684 -4.511 28.056 1.00 41.26 ? 62 ASN B CA 1 ATOM 2008 C C . ASN B 2 62 ? 106.004 -5.543 29.138 1.00 43.15 ? 62 ASN B C 1 ATOM 2009 O O . ASN B 2 62 ? 107.057 -6.184 29.099 1.00 43.34 ? 62 ASN B O 1 ATOM 2010 C CB . ASN B 2 62 ? 106.508 -3.243 28.249 1.00 38.87 ? 62 ASN B CB 1 ATOM 2011 C CG . ASN B 2 62 ? 106.524 -2.380 27.007 1.00 39.10 ? 62 ASN B CG 1 ATOM 2012 O OD1 . ASN B 2 62 ? 106.865 -1.199 27.053 1.00 38.18 ? 62 ASN B OD1 1 ATOM 2013 N ND2 . ASN B 2 62 ? 106.158 -2.975 25.878 1.00 37.23 ? 62 ASN B ND2 1 ATOM 2014 N N . SER B 2 63 ? 105.100 -5.720 30.099 1.00 44.10 ? 63 SER B N 1 ATOM 2015 C CA . SER B 2 63 ? 105.332 -6.703 31.154 1.00 44.78 ? 63 SER B CA 1 ATOM 2016 C C . SER B 2 63 ? 105.046 -8.111 30.617 1.00 46.05 ? 63 SER B C 1 ATOM 2017 O O . SER B 2 63 ? 105.660 -9.083 31.048 1.00 48.35 ? 63 SER B O 1 ATOM 2018 C CB . SER B 2 63 ? 104.464 -6.405 32.389 1.00 43.36 ? 63 SER B CB 1 ATOM 2019 O OG . SER B 2 63 ? 103.211 -7.066 32.347 1.00 46.54 ? 63 SER B OG 1 ATOM 2020 N N . GLN B 2 64 ? 104.119 -8.225 29.673 1.00 45.47 ? 64 GLN B N 1 ATOM 2021 C CA . GLN B 2 64 ? 103.822 -9.526 29.098 1.00 47.34 ? 64 GLN B CA 1 ATOM 2022 C C . GLN B 2 64 ? 104.872 -9.798 28.026 1.00 51.48 ? 64 GLN B C 1 ATOM 2023 O O . GLN B 2 64 ? 104.653 -9.534 26.841 1.00 52.49 ? 64 GLN B O 1 ATOM 2024 C CB . GLN B 2 64 ? 102.435 -9.535 28.470 1.00 45.02 ? 64 GLN B CB 1 ATOM 2025 C CG . GLN B 2 64 ? 101.575 -8.356 28.840 1.00 44.81 ? 64 GLN B CG 1 ATOM 2026 C CD . GLN B 2 64 ? 100.133 -8.756 29.063 1.00 49.44 ? 64 GLN B CD 1 ATOM 2027 O OE1 . GLN B 2 64 ? 99.537 -9.488 28.266 1.00 49.76 ? 64 GLN B OE1 1 ATOM 2028 N NE2 . GLN B 2 64 ? 99.561 -8.278 30.155 1.00 51.92 ? 64 GLN B NE2 1 ATOM 2029 N N . LYS B 2 65 ? 106.022 -10.316 28.450 1.00 53.60 ? 65 LYS B N 1 ATOM 2030 C CA . LYS B 2 65 ? 107.110 -10.613 27.529 1.00 54.75 ? 65 LYS B CA 1 ATOM 2031 C C . LYS B 2 65 ? 106.702 -11.548 26.408 1.00 53.70 ? 65 LYS B C 1 ATOM 2032 O O . LYS B 2 65 ? 107.230 -11.450 25.307 1.00 52.11 ? 65 LYS B O 1 ATOM 2033 C CB . LYS B 2 65 ? 108.295 -11.206 28.283 1.00 59.74 ? 65 LYS B CB 1 ATOM 2034 C CG . LYS B 2 65 ? 109.151 -10.171 29.002 1.00 68.81 ? 65 LYS B CG 1 ATOM 2035 C CD . LYS B 2 65 ? 109.916 -9.287 28.016 1.00 75.89 ? 65 LYS B CD 1 ATOM 2036 C CE . LYS B 2 65 ? 110.932 -10.087 27.197 1.00 79.60 ? 65 LYS B CE 1 ATOM 2037 N NZ . LYS B 2 65 ? 110.311 -11.165 26.366 1.00 79.82 ? 65 LYS B NZ 1 ATOM 2038 N N . ASP B 2 66 ? 105.769 -12.455 26.687 1.00 54.65 ? 66 ASP B N 1 ATOM 2039 C CA . ASP B 2 66 ? 105.302 -13.388 25.668 1.00 55.18 ? 66 ASP B CA 1 ATOM 2040 C C . ASP B 2 66 ? 104.606 -12.631 24.558 1.00 54.53 ? 66 ASP B C 1 ATOM 2041 O O . ASP B 2 66 ? 105.067 -12.630 23.424 1.00 57.80 ? 66 ASP B O 1 ATOM 2042 C CB . ASP B 2 66 ? 104.347 -14.424 26.256 1.00 59.21 ? 66 ASP B CB 1 ATOM 2043 C CG . ASP B 2 66 ? 105.081 -15.611 26.866 1.00 64.87 ? 66 ASP B CG 1 ATOM 2044 O OD1 . ASP B 2 66 ? 106.110 -16.035 26.289 1.00 67.45 ? 66 ASP B OD1 1 ATOM 2045 O OD2 . ASP B 2 66 ? 104.625 -16.131 27.909 1.00 66.28 ? 66 ASP B OD2 1 ATOM 2046 N N . PHE B 2 67 ? 103.493 -11.986 24.882 1.00 52.08 ? 67 PHE B N 1 ATOM 2047 C CA . PHE B 2 67 ? 102.756 -11.198 23.897 1.00 46.49 ? 67 PHE B CA 1 ATOM 2048 C C . PHE B 2 67 ? 103.684 -10.245 23.145 1.00 42.73 ? 67 PHE B C 1 ATOM 2049 O O . PHE B 2 67 ? 103.649 -10.162 21.916 1.00 38.92 ? 67 PHE B O 1 ATOM 2050 C CB . PHE B 2 67 ? 101.681 -10.387 24.599 1.00 47.60 ? 67 PHE B CB 1 ATOM 2051 C CG . PHE B 2 67 ? 101.087 -9.314 23.752 1.00 47.16 ? 67 PHE B CG 1 ATOM 2052 C CD1 . PHE B 2 67 ? 100.336 -9.633 22.636 1.00 46.64 ? 67 PHE B CD1 1 ATOM 2053 C CD2 . PHE B 2 67 ? 101.242 -7.979 24.100 1.00 49.79 ? 67 PHE B CD2 1 ATOM 2054 C CE1 . PHE B 2 67 ? 99.742 -8.642 21.885 1.00 50.19 ? 67 PHE B CE1 1 ATOM 2055 C CE2 . PHE B 2 67 ? 100.651 -6.977 23.355 1.00 51.20 ? 67 PHE B CE2 1 ATOM 2056 C CZ . PHE B 2 67 ? 99.897 -7.307 22.247 1.00 51.90 ? 67 PHE B CZ 1 ATOM 2057 N N . LEU B 2 68 ? 104.503 -9.524 23.904 1.00 39.40 ? 68 LEU B N 1 ATOM 2058 C CA . LEU B 2 68 ? 105.451 -8.571 23.345 1.00 38.46 ? 68 LEU B CA 1 ATOM 2059 C C . LEU B 2 68 ? 106.326 -9.246 22.287 1.00 40.28 ? 68 LEU B C 1 ATOM 2060 O O . LEU B 2 68 ? 106.906 -8.595 21.416 1.00 38.38 ? 68 LEU B O 1 ATOM 2061 C CB . LEU B 2 68 ? 106.341 -8.027 24.453 1.00 33.29 ? 68 LEU B CB 1 ATOM 2062 C CG . LEU B 2 68 ? 106.985 -6.694 24.107 1.00 31.40 ? 68 LEU B CG 1 ATOM 2063 C CD1 . LEU B 2 68 ? 106.115 -5.570 24.654 1.00 28.65 ? 68 LEU B CD1 1 ATOM 2064 C CD2 . LEU B 2 68 ? 108.371 -6.629 24.696 1.00 30.46 ? 68 LEU B CD2 1 ATOM 2065 N N . GLU B 2 69 ? 106.413 -10.565 22.384 1.00 42.44 ? 69 GLU B N 1 ATOM 2066 C CA . GLU B 2 69 ? 107.209 -11.366 21.472 1.00 44.09 ? 69 GLU B CA 1 ATOM 2067 C C . GLU B 2 69 ? 106.396 -11.599 20.224 1.00 44.68 ? 69 GLU B C 1 ATOM 2068 O O . GLU B 2 69 ? 106.838 -11.326 19.117 1.00 44.50 ? 69 GLU B O 1 ATOM 2069 C CB . GLU B 2 69 ? 107.526 -12.708 22.120 1.00 48.13 ? 69 GLU B CB 1 ATOM 2070 C CG . GLU B 2 69 ? 108.695 -13.426 21.518 1.00 59.08 ? 69 GLU B CG 1 ATOM 2071 C CD . GLU B 2 69 ? 109.952 -12.592 21.602 1.00 68.43 ? 69 GLU B CD 1 ATOM 2072 O OE1 . GLU B 2 69 ? 110.234 -12.054 22.699 1.00 69.59 ? 69 GLU B OE1 1 ATOM 2073 O OE2 . GLU B 2 69 ? 110.657 -12.473 20.574 1.00 74.29 ? 69 GLU B OE2 1 ATOM 2074 N N . ASP B 2 70 ? 105.192 -12.109 20.432 1.00 48.09 ? 70 ASP B N 1 ATOM 2075 C CA . ASP B 2 70 ? 104.265 -12.413 19.360 1.00 51.37 ? 70 ASP B CA 1 ATOM 2076 C C . ASP B 2 70 ? 104.130 -11.252 18.396 1.00 52.74 ? 70 ASP B C 1 ATOM 2077 O O . ASP B 2 70 ? 104.077 -11.447 17.183 1.00 54.06 ? 70 ASP B O 1 ATOM 2078 C CB . ASP B 2 70 ? 102.895 -12.743 19.939 1.00 55.68 ? 70 ASP B CB 1 ATOM 2079 C CG . ASP B 2 70 ? 101.904 -13.148 18.878 1.00 62.34 ? 70 ASP B CG 1 ATOM 2080 O OD1 . ASP B 2 70 ? 100.705 -13.269 19.200 1.00 68.67 ? 70 ASP B OD1 1 ATOM 2081 O OD2 . ASP B 2 70 ? 102.320 -13.350 17.718 1.00 68.31 ? 70 ASP B OD2 1 ATOM 2082 N N . ARG B 2 71 ? 104.063 -10.041 18.934 1.00 53.53 ? 71 ARG B N 1 ATOM 2083 C CA . ARG B 2 71 ? 103.931 -8.868 18.087 1.00 52.99 ? 71 ARG B CA 1 ATOM 2084 C C . ARG B 2 71 ? 105.128 -8.715 17.163 1.00 50.91 ? 71 ARG B C 1 ATOM 2085 O O . ARG B 2 71 ? 105.014 -8.152 16.080 1.00 51.04 ? 71 ARG B O 1 ATOM 2086 C CB . ARG B 2 71 ? 103.743 -7.620 18.941 1.00 55.68 ? 71 ARG B CB 1 ATOM 2087 C CG . ARG B 2 71 ? 102.414 -7.620 19.675 1.00 61.75 ? 71 ARG B CG 1 ATOM 2088 C CD . ARG B 2 71 ? 101.219 -7.484 18.721 1.00 65.93 ? 71 ARG B CD 1 ATOM 2089 N NE . ARG B 2 71 ? 100.665 -6.128 18.745 1.00 69.39 ? 71 ARG B NE 1 ATOM 2090 C CZ . ARG B 2 71 ? 99.369 -5.846 18.876 1.00 70.12 ? 71 ARG B CZ 1 ATOM 2091 N NH1 . ARG B 2 71 ? 98.479 -6.826 18.995 1.00 71.12 ? 71 ARG B NH1 1 ATOM 2092 N NH2 . ARG B 2 71 ? 98.961 -4.582 18.899 1.00 66.58 ? 71 ARG B NH2 1 ATOM 2093 N N . ARG B 2 72 ? 106.279 -9.224 17.578 1.00 49.37 ? 72 ARG B N 1 ATOM 2094 C CA . ARG B 2 72 ? 107.452 -9.137 16.728 1.00 48.89 ? 72 ARG B CA 1 ATOM 2095 C C . ARG B 2 72 ? 107.231 -10.063 15.532 1.00 47.09 ? 72 ARG B C 1 ATOM 2096 O O . ARG B 2 72 ? 107.708 -9.812 14.433 1.00 44.39 ? 72 ARG B O 1 ATOM 2097 C CB . ARG B 2 72 ? 108.686 -9.556 17.512 1.00 53.73 ? 72 ARG B CB 1 ATOM 2098 C CG . ARG B 2 72 ? 109.883 -8.648 17.321 1.00 64.48 ? 72 ARG B CG 1 ATOM 2099 C CD . ARG B 2 72 ? 110.812 -8.740 18.528 1.00 77.08 ? 72 ARG B CD 1 ATOM 2100 N NE . ARG B 2 72 ? 110.048 -8.707 19.777 1.00 88.44 ? 72 ARG B NE 1 ATOM 2101 C CZ . ARG B 2 72 ? 110.568 -8.443 20.974 1.00 94.02 ? 72 ARG B CZ 1 ATOM 2102 N NH1 . ARG B 2 72 ? 111.866 -8.183 21.097 1.00 96.72 ? 72 ARG B NH1 1 ATOM 2103 N NH2 . ARG B 2 72 ? 109.789 -8.435 22.054 1.00 95.59 ? 72 ARG B NH2 1 ATOM 2104 N N . ALA B 2 73 ? 106.467 -11.125 15.755 1.00 47.66 ? 73 ALA B N 1 ATOM 2105 C CA . ALA B 2 73 ? 106.177 -12.105 14.716 1.00 48.16 ? 73 ALA B CA 1 ATOM 2106 C C . ALA B 2 73 ? 105.344 -11.548 13.578 1.00 48.94 ? 73 ALA B C 1 ATOM 2107 O O . ALA B 2 73 ? 105.400 -12.054 12.458 1.00 52.32 ? 73 ALA B O 1 ATOM 2108 C CB . ALA B 2 73 ? 105.462 -13.305 15.320 1.00 49.49 ? 73 ALA B CB 1 ATOM 2109 N N . ALA B 2 74 ? 104.552 -10.522 13.862 1.00 46.75 ? 74 ALA B N 1 ATOM 2110 C CA . ALA B 2 74 ? 103.706 -9.934 12.834 1.00 42.76 ? 74 ALA B CA 1 ATOM 2111 C C . ALA B 2 74 ? 104.456 -9.780 11.506 1.00 41.05 ? 74 ALA B C 1 ATOM 2112 O O . ALA B 2 74 ? 103.913 -10.089 10.438 1.00 35.55 ? 74 ALA B O 1 ATOM 2113 C CB . ALA B 2 74 ? 103.187 -8.590 13.305 1.00 41.54 ? 74 ALA B CB 1 ATOM 2114 N N . VAL B 2 75 ? 105.708 -9.326 11.580 1.00 39.56 ? 75 VAL B N 1 ATOM 2115 C CA . VAL B 2 75 ? 106.522 -9.121 10.385 1.00 37.05 ? 75 VAL B CA 1 ATOM 2116 C C . VAL B 2 75 ? 106.420 -10.311 9.483 1.00 37.25 ? 75 VAL B C 1 ATOM 2117 O O . VAL B 2 75 ? 106.830 -10.240 8.334 1.00 39.83 ? 75 VAL B O 1 ATOM 2118 C CB . VAL B 2 75 ? 108.001 -8.942 10.701 1.00 33.88 ? 75 VAL B CB 1 ATOM 2119 C CG1 . VAL B 2 75 ? 108.276 -7.550 11.237 1.00 33.55 ? 75 VAL B CG1 1 ATOM 2120 C CG2 . VAL B 2 75 ? 108.407 -9.982 11.696 1.00 36.36 ? 75 VAL B CG2 1 ATOM 2121 N N . ASP B 2 76 ? 105.895 -11.411 10.011 1.00 38.96 ? 76 ASP B N 1 ATOM 2122 C CA . ASP B 2 76 ? 105.740 -12.626 9.229 1.00 39.42 ? 76 ASP B CA 1 ATOM 2123 C C . ASP B 2 76 ? 104.289 -13.062 9.200 1.00 37.50 ? 76 ASP B C 1 ATOM 2124 O O . ASP B 2 76 ? 103.694 -13.183 8.134 1.00 38.67 ? 76 ASP B O 1 ATOM 2125 C CB . ASP B 2 76 ? 106.612 -13.764 9.791 1.00 41.58 ? 76 ASP B CB 1 ATOM 2126 C CG . ASP B 2 76 ? 108.117 -13.524 9.586 1.00 46.79 ? 76 ASP B CG 1 ATOM 2127 O OD1 . ASP B 2 76 ? 108.534 -13.192 8.455 1.00 46.05 ? 76 ASP B OD1 1 ATOM 2128 O OD2 . ASP B 2 76 ? 108.895 -13.679 10.556 1.00 51.95 ? 76 ASP B OD2 1 ATOM 2129 N N . THR B 2 77 ? 103.720 -13.287 10.374 1.00 35.21 ? 77 THR B N 1 ATOM 2130 C CA . THR B 2 77 ? 102.341 -13.735 10.475 1.00 39.26 ? 77 THR B CA 1 ATOM 2131 C C . THR B 2 77 ? 101.352 -12.764 9.840 1.00 39.79 ? 77 THR B C 1 ATOM 2132 O O . THR B 2 77 ? 100.357 -13.184 9.241 1.00 39.47 ? 77 THR B O 1 ATOM 2133 C CB . THR B 2 77 ? 101.951 -13.924 11.944 1.00 44.12 ? 77 THR B CB 1 ATOM 2134 O OG1 . THR B 2 77 ? 102.060 -12.672 12.634 1.00 51.28 ? 77 THR B OG1 1 ATOM 2135 C CG2 . THR B 2 77 ? 102.875 -14.909 12.615 1.00 47.21 ? 77 THR B CG2 1 ATOM 2136 N N . TYR B 2 78 ? 101.644 -11.469 9.969 1.00 39.90 ? 78 TYR B N 1 ATOM 2137 C CA . TYR B 2 78 ? 100.790 -10.389 9.457 1.00 36.31 ? 78 TYR B CA 1 ATOM 2138 C C . TYR B 2 78 ? 101.336 -9.677 8.221 1.00 35.35 ? 78 TYR B C 1 ATOM 2139 O O . TYR B 2 78 ? 100.705 -9.682 7.164 1.00 36.82 ? 78 TYR B O 1 ATOM 2140 C CB . TYR B 2 78 ? 100.565 -9.374 10.575 1.00 34.29 ? 78 TYR B CB 1 ATOM 2141 C CG . TYR B 2 78 ? 99.798 -8.118 10.213 1.00 32.26 ? 78 TYR B CG 1 ATOM 2142 C CD1 . TYR B 2 78 ? 98.439 -8.158 9.913 1.00 29.36 ? 78 TYR B CD1 1 ATOM 2143 C CD2 . TYR B 2 78 ? 100.424 -6.869 10.250 1.00 35.04 ? 78 TYR B CD2 1 ATOM 2144 C CE1 . TYR B 2 78 ? 97.720 -6.978 9.667 1.00 33.01 ? 78 TYR B CE1 1 ATOM 2145 C CE2 . TYR B 2 78 ? 99.720 -5.691 10.006 1.00 34.47 ? 78 TYR B CE2 1 ATOM 2146 C CZ . TYR B 2 78 ? 98.373 -5.750 9.718 1.00 34.04 ? 78 TYR B CZ 1 ATOM 2147 O OH . TYR B 2 78 ? 97.690 -4.576 9.496 1.00 33.21 ? 78 TYR B OH 1 ATOM 2148 N N . CYS B 2 79 ? 102.504 -9.061 8.346 1.00 32.92 ? 79 CYS B N 1 ATOM 2149 C CA . CYS B 2 79 ? 103.088 -8.352 7.219 1.00 35.00 ? 79 CYS B CA 1 ATOM 2150 C C . CYS B 2 79 ? 103.378 -9.225 5.995 1.00 34.59 ? 79 CYS B C 1 ATOM 2151 O O . CYS B 2 79 ? 102.593 -9.254 5.050 1.00 35.09 ? 79 CYS B O 1 ATOM 2152 C CB . CYS B 2 79 ? 104.354 -7.624 7.663 1.00 38.44 ? 79 CYS B CB 1 ATOM 2153 S SG . CYS B 2 79 ? 104.008 -6.231 8.791 1.00 44.78 ? 79 CYS B SG 1 ATOM 2154 N N . ARG B 2 80 ? 104.496 -9.937 5.999 1.00 34.26 ? 80 ARG B N 1 ATOM 2155 C CA . ARG B 2 80 ? 104.833 -10.788 4.864 1.00 33.90 ? 80 ARG B CA 1 ATOM 2156 C C . ARG B 2 80 ? 103.683 -11.628 4.330 1.00 31.60 ? 80 ARG B C 1 ATOM 2157 O O . ARG B 2 80 ? 103.647 -11.919 3.145 1.00 30.32 ? 80 ARG B O 1 ATOM 2158 C CB . ARG B 2 80 ? 106.013 -11.690 5.209 1.00 39.08 ? 80 ARG B CB 1 ATOM 2159 C CG . ARG B 2 80 ? 107.362 -11.041 4.922 1.00 44.92 ? 80 ARG B CG 1 ATOM 2160 C CD . ARG B 2 80 ? 108.464 -11.620 5.795 1.00 50.18 ? 80 ARG B CD 1 ATOM 2161 N NE . ARG B 2 80 ? 109.749 -10.982 5.536 1.00 53.43 ? 80 ARG B NE 1 ATOM 2162 C CZ . ARG B 2 80 ? 110.771 -10.985 6.387 1.00 56.04 ? 80 ARG B CZ 1 ATOM 2163 N NH1 . ARG B 2 80 ? 110.666 -11.590 7.565 1.00 55.13 ? 80 ARG B NH1 1 ATOM 2164 N NH2 . ARG B 2 80 ? 111.902 -10.380 6.053 1.00 56.89 ? 80 ARG B NH2 1 ATOM 2165 N N . HIS B 2 81 ? 102.750 -12.028 5.190 1.00 32.17 ? 81 HIS B N 1 ATOM 2166 C CA . HIS B 2 81 ? 101.610 -12.819 4.735 1.00 33.79 ? 81 HIS B CA 1 ATOM 2167 C C . HIS B 2 81 ? 100.700 -11.964 3.858 1.00 36.49 ? 81 HIS B C 1 ATOM 2168 O O . HIS B 2 81 ? 100.442 -12.292 2.698 1.00 38.03 ? 81 HIS B O 1 ATOM 2169 C CB . HIS B 2 81 ? 100.786 -13.352 5.909 1.00 32.46 ? 81 HIS B CB 1 ATOM 2170 C CG . HIS B 2 81 ? 99.489 -13.972 5.487 1.00 35.36 ? 81 HIS B CG 1 ATOM 2171 N ND1 . HIS B 2 81 ? 99.410 -15.230 4.932 1.00 36.89 ? 81 HIS B ND1 1 ATOM 2172 C CD2 . HIS B 2 81 ? 98.228 -13.478 5.472 1.00 37.44 ? 81 HIS B CD2 1 ATOM 2173 C CE1 . HIS B 2 81 ? 98.158 -15.484 4.593 1.00 34.93 ? 81 HIS B CE1 1 ATOM 2174 N NE2 . HIS B 2 81 ? 97.420 -14.437 4.909 1.00 32.94 ? 81 HIS B NE2 1 ATOM 2175 N N . ASN B 2 82 ? 100.204 -10.866 4.419 1.00 38.04 ? 82 ASN B N 1 ATOM 2176 C CA . ASN B 2 82 ? 99.323 -9.979 3.673 1.00 39.28 ? 82 ASN B CA 1 ATOM 2177 C C . ASN B 2 82 ? 99.964 -9.486 2.381 1.00 40.10 ? 82 ASN B C 1 ATOM 2178 O O . ASN B 2 82 ? 99.272 -9.180 1.413 1.00 43.08 ? 82 ASN B O 1 ATOM 2179 C CB . ASN B 2 82 ? 98.912 -8.779 4.531 1.00 36.51 ? 82 ASN B CB 1 ATOM 2180 C CG . ASN B 2 82 ? 97.843 -9.125 5.544 1.00 34.81 ? 82 ASN B CG 1 ATOM 2181 O OD1 . ASN B 2 82 ? 96.844 -9.770 5.227 1.00 32.08 ? 82 ASN B OD1 1 ATOM 2182 N ND2 . ASN B 2 82 ? 98.040 -8.681 6.768 1.00 38.93 ? 82 ASN B ND2 1 ATOM 2183 N N . TYR B 2 83 ? 101.287 -9.414 2.363 1.00 39.87 ? 83 TYR B N 1 ATOM 2184 C CA . TYR B 2 83 ? 101.981 -8.951 1.178 1.00 41.23 ? 83 TYR B CA 1 ATOM 2185 C C . TYR B 2 83 ? 101.638 -9.833 -0.012 1.00 41.76 ? 83 TYR B C 1 ATOM 2186 O O . TYR B 2 83 ? 101.124 -9.360 -1.022 1.00 47.74 ? 83 TYR B O 1 ATOM 2187 C CB . TYR B 2 83 ? 103.490 -8.964 1.409 1.00 43.53 ? 83 TYR B CB 1 ATOM 2188 C CG . TYR B 2 83 ? 104.288 -8.258 0.336 1.00 44.48 ? 83 TYR B CG 1 ATOM 2189 C CD1 . TYR B 2 83 ? 104.165 -8.619 -1.004 1.00 45.13 ? 83 TYR B CD1 1 ATOM 2190 C CD2 . TYR B 2 83 ? 105.161 -7.221 0.662 1.00 44.08 ? 83 TYR B CD2 1 ATOM 2191 C CE1 . TYR B 2 83 ? 104.885 -7.964 -1.995 1.00 49.81 ? 83 TYR B CE1 1 ATOM 2192 C CE2 . TYR B 2 83 ? 105.890 -6.560 -0.317 1.00 47.90 ? 83 TYR B CE2 1 ATOM 2193 C CZ . TYR B 2 83 ? 105.746 -6.936 -1.648 1.00 51.31 ? 83 TYR B CZ 1 ATOM 2194 O OH . TYR B 2 83 ? 106.460 -6.289 -2.633 1.00 52.42 ? 83 TYR B OH 1 ATOM 2195 N N . GLY B 2 84 ? 101.917 -11.121 0.112 1.00 40.53 ? 84 GLY B N 1 ATOM 2196 C CA . GLY B 2 84 ? 101.648 -12.034 -0.979 1.00 39.59 ? 84 GLY B CA 1 ATOM 2197 C C . GLY B 2 84 ? 100.183 -12.308 -1.230 1.00 37.89 ? 84 GLY B C 1 ATOM 2198 O O . GLY B 2 84 ? 99.803 -12.716 -2.331 1.00 41.58 ? 84 GLY B O 1 ATOM 2199 N N . VAL B 2 85 ? 99.350 -12.085 -0.223 1.00 35.18 ? 85 VAL B N 1 ATOM 2200 C CA . VAL B 2 85 ? 97.927 -12.339 -0.386 1.00 34.73 ? 85 VAL B CA 1 ATOM 2201 C C . VAL B 2 85 ? 97.331 -11.517 -1.511 1.00 37.14 ? 85 VAL B C 1 ATOM 2202 O O . VAL B 2 85 ? 96.188 -11.736 -1.907 1.00 38.29 ? 85 VAL B O 1 ATOM 2203 C CB . VAL B 2 85 ? 97.146 -12.031 0.890 1.00 30.78 ? 85 VAL B CB 1 ATOM 2204 C CG1 . VAL B 2 85 ? 95.684 -12.361 0.680 1.00 21.85 ? 85 VAL B CG1 1 ATOM 2205 C CG2 . VAL B 2 85 ? 97.723 -12.824 2.052 1.00 31.88 ? 85 VAL B CG2 1 ATOM 2206 N N . GLY B 2 86 ? 98.100 -10.564 -2.024 1.00 40.54 ? 86 GLY B N 1 ATOM 2207 C CA . GLY B 2 86 ? 97.592 -9.740 -3.099 1.00 42.72 ? 86 GLY B CA 1 ATOM 2208 C C . GLY B 2 86 ? 98.605 -8.892 -3.836 1.00 44.58 ? 86 GLY B C 1 ATOM 2209 O O . GLY B 2 86 ? 98.271 -7.809 -4.297 1.00 45.07 ? 86 GLY B O 1 ATOM 2210 N N . GLU B 2 87 ? 99.840 -9.359 -3.953 1.00 47.77 ? 87 GLU B N 1 ATOM 2211 C CA . GLU B 2 87 ? 100.836 -8.593 -4.686 1.00 53.91 ? 87 GLU B CA 1 ATOM 2212 C C . GLU B 2 87 ? 100.445 -8.681 -6.158 1.00 55.64 ? 87 GLU B C 1 ATOM 2213 O O . GLU B 2 87 ? 100.849 -7.863 -6.994 1.00 55.86 ? 87 GLU B O 1 ATOM 2214 C CB . GLU B 2 87 ? 102.218 -9.196 -4.487 1.00 57.83 ? 87 GLU B CB 1 ATOM 2215 C CG . GLU B 2 87 ? 102.300 -10.648 -4.872 1.00 65.59 ? 87 GLU B CG 1 ATOM 2216 C CD . GLU B 2 87 ? 103.727 -11.144 -4.938 1.00 74.19 ? 87 GLU B CD 1 ATOM 2217 O OE1 . GLU B 2 87 ? 103.913 -12.375 -5.048 1.00 80.62 ? 87 GLU B OE1 1 ATOM 2218 O OE2 . GLU B 2 87 ? 104.662 -10.308 -4.890 1.00 74.84 ? 87 GLU B OE2 1 ATOM 2219 N N . SER B 2 88 ? 99.634 -9.690 -6.450 1.00 56.81 ? 88 SER B N 1 ATOM 2220 C CA . SER B 2 88 ? 99.139 -9.960 -7.791 1.00 56.48 ? 88 SER B CA 1 ATOM 2221 C C . SER B 2 88 ? 98.418 -8.757 -8.383 1.00 55.25 ? 88 SER B C 1 ATOM 2222 O O . SER B 2 88 ? 98.515 -8.500 -9.580 1.00 55.56 ? 88 SER B O 1 ATOM 2223 C CB . SER B 2 88 ? 98.188 -11.148 -7.734 1.00 57.99 ? 88 SER B CB 1 ATOM 2224 O OG . SER B 2 88 ? 98.610 -12.059 -6.729 1.00 62.20 ? 88 SER B OG 1 ATOM 2225 N N . PHE B 2 89 ? 97.695 -8.027 -7.538 1.00 55.44 ? 89 PHE B N 1 ATOM 2226 C CA . PHE B 2 89 ? 96.949 -6.850 -7.975 1.00 52.82 ? 89 PHE B CA 1 ATOM 2227 C C . PHE B 2 89 ? 97.359 -5.542 -7.308 1.00 49.07 ? 89 PHE B C 1 ATOM 2228 O O . PHE B 2 89 ? 96.543 -4.647 -7.161 1.00 49.57 ? 89 PHE B O 1 ATOM 2229 C CB . PHE B 2 89 ? 95.438 -7.072 -7.790 1.00 53.50 ? 89 PHE B CB 1 ATOM 2230 C CG . PHE B 2 89 ? 95.025 -7.424 -6.379 1.00 55.30 ? 89 PHE B CG 1 ATOM 2231 C CD1 . PHE B 2 89 ? 94.050 -8.399 -6.151 1.00 57.87 ? 89 PHE B CD1 1 ATOM 2232 C CD2 . PHE B 2 89 ? 95.591 -6.789 -5.283 1.00 52.78 ? 89 PHE B CD2 1 ATOM 2233 C CE1 . PHE B 2 89 ? 93.646 -8.737 -4.852 1.00 55.98 ? 89 PHE B CE1 1 ATOM 2234 C CE2 . PHE B 2 89 ? 95.193 -7.119 -3.984 1.00 55.06 ? 89 PHE B CE2 1 ATOM 2235 C CZ . PHE B 2 89 ? 94.216 -8.098 -3.770 1.00 53.77 ? 89 PHE B CZ 1 ATOM 2236 N N . THR B 2 90 ? 98.614 -5.435 -6.890 1.00 45.60 ? 90 THR B N 1 ATOM 2237 C CA . THR B 2 90 ? 99.095 -4.203 -6.278 1.00 43.02 ? 90 THR B CA 1 ATOM 2238 C C . THR B 2 90 ? 100.554 -4.007 -6.650 1.00 41.91 ? 90 THR B C 1 ATOM 2239 O O . THR B 2 90 ? 100.882 -3.111 -7.418 1.00 42.88 ? 90 THR B O 1 ATOM 2240 C CB . THR B 2 90 ? 98.969 -4.199 -4.729 1.00 43.92 ? 90 THR B CB 1 ATOM 2241 O OG1 . THR B 2 90 ? 99.906 -5.118 -4.160 1.00 45.35 ? 90 THR B OG1 1 ATOM 2242 C CG2 . THR B 2 90 ? 97.567 -4.578 -4.302 1.00 41.12 ? 90 THR B CG2 1 ATOM 2243 N N . VAL B 2 91 ? 101.442 -4.836 -6.118 1.00 40.15 ? 91 VAL B N 1 ATOM 2244 C CA . VAL B 2 91 ? 102.844 -4.683 -6.463 1.00 38.79 ? 91 VAL B CA 1 ATOM 2245 C C . VAL B 2 91 ? 102.945 -4.827 -7.974 1.00 39.60 ? 91 VAL B C 1 ATOM 2246 O O . VAL B 2 91 ? 103.663 -4.089 -8.645 1.00 39.23 ? 91 VAL B O 1 ATOM 2247 C CB . VAL B 2 91 ? 103.732 -5.764 -5.818 1.00 35.71 ? 91 VAL B CB 1 ATOM 2248 C CG1 . VAL B 2 91 ? 105.186 -5.414 -6.039 1.00 36.51 ? 91 VAL B CG1 1 ATOM 2249 C CG2 . VAL B 2 91 ? 103.450 -5.875 -4.339 1.00 34.18 ? 91 VAL B CG2 1 ATOM 2250 N N . GLN B 2 92 ? 102.190 -5.770 -8.511 1.00 40.53 ? 92 GLN B N 1 ATOM 2251 C CA . GLN B 2 92 ? 102.230 -6.013 -9.932 1.00 45.57 ? 92 GLN B CA 1 ATOM 2252 C C . GLN B 2 92 ? 101.125 -5.376 -10.729 1.00 45.75 ? 92 GLN B C 1 ATOM 2253 O O . GLN B 2 92 ? 100.726 -5.887 -11.771 1.00 48.32 ? 92 GLN B O 1 ATOM 2254 C CB . GLN B 2 92 ? 102.227 -7.501 -10.190 1.00 51.14 ? 92 GLN B CB 1 ATOM 2255 C CG . GLN B 2 92 ? 103.482 -8.168 -9.747 1.00 59.85 ? 92 GLN B CG 1 ATOM 2256 C CD . GLN B 2 92 ? 103.376 -9.643 -9.918 1.00 68.30 ? 92 GLN B CD 1 ATOM 2257 O OE1 . GLN B 2 92 ? 102.535 -10.287 -9.290 1.00 73.07 ? 92 GLN B OE1 1 ATOM 2258 N NE2 . GLN B 2 92 ? 104.212 -10.200 -10.785 1.00 74.41 ? 92 GLN B NE2 1 ATOM 2259 N N . ARG B 2 93 ? 100.603 -4.264 -10.249 1.00 47.92 ? 93 ARG B N 1 ATOM 2260 C CA . ARG B 2 93 ? 99.556 -3.612 -11.014 1.00 45.58 ? 93 ARG B CA 1 ATOM 2261 C C . ARG B 2 93 ? 100.337 -2.850 -12.059 1.00 44.85 ? 93 ARG B C 1 ATOM 2262 O O . ARG B 2 93 ? 101.480 -2.461 -11.822 1.00 44.72 ? 93 ARG B O 1 ATOM 2263 C CB . ARG B 2 93 ? 98.739 -2.635 -10.146 1.00 39.10 ? 93 ARG B CB 1 ATOM 2264 C CG . ARG B 2 93 ? 97.497 -2.090 -10.838 1.00 29.39 ? 93 ARG B CG 1 ATOM 2265 C CD . ARG B 2 93 ? 96.835 -0.985 -10.040 1.00 24.76 ? 93 ARG B CD 1 ATOM 2266 N NE . ARG B 2 93 ? 95.856 -0.245 -10.837 1.00 22.79 ? 93 ARG B NE 1 ATOM 2267 C CZ . ARG B 2 93 ? 94.689 -0.736 -11.248 1.00 23.85 ? 93 ARG B CZ 1 ATOM 2268 N NH1 . ARG B 2 93 ? 94.334 -1.979 -10.942 1.00 24.67 ? 93 ARG B NH1 1 ATOM 2269 N NH2 . ARG B 2 93 ? 93.873 0.014 -11.970 1.00 21.79 ? 93 ARG B NH2 1 ATOM 2270 N N . ARG B 2 94 ? 99.746 -2.674 -13.227 1.00 44.07 ? 94 ARG B N 1 ATOM 2271 C CA . ARG B 2 94 ? 100.399 -1.912 -14.269 1.00 41.71 ? 94 ARG B CA 1 ATOM 2272 C C . ARG B 2 94 ? 99.403 -1.391 -15.266 1.00 41.36 ? 94 ARG B C 1 ATOM 2273 O O . ARG B 2 94 ? 98.799 -2.156 -16.020 1.00 42.26 ? 94 ARG B O 1 ATOM 2274 C CB . ARG B 2 94 ? 101.467 -2.743 -14.955 1.00 40.51 ? 94 ARG B CB 1 ATOM 2275 C CG . ARG B 2 94 ? 102.819 -2.426 -14.412 1.00 43.90 ? 94 ARG B CG 1 ATOM 2276 C CD . ARG B 2 94 ? 103.714 -3.625 -14.395 1.00 54.99 ? 94 ARG B CD 1 ATOM 2277 N NE . ARG B 2 94 ? 104.931 -3.315 -13.657 1.00 67.19 ? 94 ARG B NE 1 ATOM 2278 C CZ . ARG B 2 94 ? 104.949 -2.946 -12.378 1.00 73.86 ? 94 ARG B CZ 1 ATOM 2279 N NH1 . ARG B 2 94 ? 103.813 -2.849 -11.697 1.00 75.18 ? 94 ARG B NH1 1 ATOM 2280 N NH2 . ARG B 2 94 ? 106.103 -2.662 -11.782 1.00 76.72 ? 94 ARG B NH2 1 ATOM 2281 N N . VAL B 2 95 ? 99.208 -0.077 -15.224 1.00 40.79 ? 95 VAL B N 1 ATOM 2282 C CA . VAL B 2 95 ? 98.306 0.594 -16.134 1.00 39.31 ? 95 VAL B CA 1 ATOM 2283 C C . VAL B 2 95 ? 99.143 1.568 -16.929 1.00 43.00 ? 95 VAL B C 1 ATOM 2284 O O . VAL B 2 95 ? 99.862 2.403 -16.367 1.00 41.63 ? 95 VAL B O 1 ATOM 2285 C CB . VAL B 2 95 ? 97.234 1.340 -15.395 1.00 37.68 ? 95 VAL B CB 1 ATOM 2286 C CG1 . VAL B 2 95 ? 96.397 2.119 -16.383 1.00 38.42 ? 95 VAL B CG1 1 ATOM 2287 C CG2 . VAL B 2 95 ? 96.381 0.355 -14.620 1.00 36.08 ? 95 VAL B CG2 1 ATOM 2288 N N . GLU B 2 96 ? 99.048 1.435 -18.245 1.00 45.84 ? 96 GLU B N 1 ATOM 2289 C CA . GLU B 2 96 ? 99.814 2.242 -19.181 1.00 49.46 ? 96 GLU B CA 1 ATOM 2290 C C . GLU B 2 96 ? 99.353 3.694 -19.214 1.00 46.97 ? 96 GLU B C 1 ATOM 2291 O O . GLU B 2 96 ? 98.154 3.979 -19.295 1.00 45.91 ? 96 GLU B O 1 ATOM 2292 C CB . GLU B 2 96 ? 99.705 1.612 -20.576 1.00 57.45 ? 96 GLU B CB 1 ATOM 2293 C CG . GLU B 2 96 ? 100.859 1.901 -21.530 1.00 64.73 ? 96 GLU B CG 1 ATOM 2294 C CD . GLU B 2 96 ? 100.731 1.152 -22.860 1.00 71.01 ? 96 GLU B CD 1 ATOM 2295 O OE1 . GLU B 2 96 ? 99.837 1.487 -23.674 1.00 71.64 ? 96 GLU B OE1 1 ATOM 2296 O OE2 . GLU B 2 96 ? 101.531 0.218 -23.086 1.00 75.98 ? 96 GLU B OE2 1 ATOM 2297 N N . PRO B 2 97 ? 100.309 4.634 -19.152 1.00 44.35 ? 97 PRO B N 1 ATOM 2298 C CA . PRO B 2 97 ? 100.042 6.075 -19.175 1.00 45.07 ? 97 PRO B CA 1 ATOM 2299 C C . PRO B 2 97 ? 99.340 6.442 -20.465 1.00 48.11 ? 97 PRO B C 1 ATOM 2300 O O . PRO B 2 97 ? 99.561 5.798 -21.488 1.00 52.36 ? 97 PRO B O 1 ATOM 2301 C CB . PRO B 2 97 ? 101.435 6.693 -19.144 1.00 42.31 ? 97 PRO B CB 1 ATOM 2302 C CG . PRO B 2 97 ? 102.280 5.648 -18.529 1.00 43.40 ? 97 PRO B CG 1 ATOM 2303 C CD . PRO B 2 97 ? 101.753 4.368 -19.093 1.00 40.95 ? 97 PRO B CD 1 ATOM 2304 N N . LYS B 2 98 ? 98.489 7.458 -20.427 1.00 49.07 ? 98 LYS B N 1 ATOM 2305 C CA . LYS B 2 98 ? 97.828 7.917 -21.643 1.00 50.55 ? 98 LYS B CA 1 ATOM 2306 C C . LYS B 2 98 ? 98.363 9.327 -21.817 1.00 52.30 ? 98 LYS B C 1 ATOM 2307 O O . LYS B 2 98 ? 97.927 10.239 -21.120 1.00 55.88 ? 98 LYS B O 1 ATOM 2308 C CB . LYS B 2 98 ? 96.317 7.959 -21.475 1.00 50.77 ? 98 LYS B CB 1 ATOM 2309 C CG . LYS B 2 98 ? 95.578 8.311 -22.761 1.00 58.58 ? 98 LYS B CG 1 ATOM 2310 C CD . LYS B 2 98 ? 95.554 7.125 -23.739 1.00 67.37 ? 98 LYS B CD 1 ATOM 2311 C CE . LYS B 2 98 ? 94.680 7.365 -24.990 1.00 66.25 ? 98 LYS B CE 1 ATOM 2312 N NZ . LYS B 2 98 ? 95.283 8.333 -25.958 1.00 67.59 ? 98 LYS B NZ 1 ATOM 2313 N N . VAL B 2 99 ? 99.327 9.502 -22.721 1.00 53.85 ? 99 VAL B N 1 ATOM 2314 C CA . VAL B 2 99 ? 99.938 10.813 -22.947 1.00 51.95 ? 99 VAL B CA 1 ATOM 2315 C C . VAL B 2 99 ? 99.311 11.617 -24.076 1.00 53.33 ? 99 VAL B C 1 ATOM 2316 O O . VAL B 2 99 ? 98.908 11.067 -25.102 1.00 53.46 ? 99 VAL B O 1 ATOM 2317 C CB . VAL B 2 99 ? 101.447 10.700 -23.242 1.00 48.60 ? 99 VAL B CB 1 ATOM 2318 C CG1 . VAL B 2 99 ? 102.028 12.087 -23.479 1.00 48.20 ? 99 VAL B CG1 1 ATOM 2319 C CG2 . VAL B 2 99 ? 102.158 10.021 -22.089 1.00 46.60 ? 99 VAL B CG2 1 ATOM 2320 N N . THR B 2 100 ? 99.234 12.929 -23.854 1.00 55.45 ? 100 THR B N 1 ATOM 2321 C CA . THR B 2 100 ? 98.680 13.893 -24.808 1.00 55.71 ? 100 THR B CA 1 ATOM 2322 C C . THR B 2 100 ? 99.437 15.221 -24.633 1.00 55.06 ? 100 THR B C 1 ATOM 2323 O O . THR B 2 100 ? 99.692 15.674 -23.506 1.00 52.91 ? 100 THR B O 1 ATOM 2324 C CB . THR B 2 100 ? 97.140 14.123 -24.592 1.00 54.28 ? 100 THR B CB 1 ATOM 2325 O OG1 . THR B 2 100 ? 96.894 14.549 -23.247 1.00 57.56 ? 100 THR B OG1 1 ATOM 2326 C CG2 . THR B 2 100 ? 96.353 12.837 -24.848 1.00 51.57 ? 100 THR B CG2 1 ATOM 2327 N N . VAL B 2 101 ? 99.826 15.821 -25.753 1.00 53.87 ? 101 VAL B N 1 ATOM 2328 C CA . VAL B 2 101 ? 100.556 17.077 -25.722 1.00 50.25 ? 101 VAL B CA 1 ATOM 2329 C C . VAL B 2 101 ? 99.821 18.112 -26.520 1.00 51.89 ? 101 VAL B C 1 ATOM 2330 O O . VAL B 2 101 ? 99.615 17.945 -27.717 1.00 52.09 ? 101 VAL B O 1 ATOM 2331 C CB . VAL B 2 101 ? 101.975 16.934 -26.301 1.00 45.86 ? 101 VAL B CB 1 ATOM 2332 C CG1 . VAL B 2 101 ? 102.574 18.299 -26.570 1.00 39.83 ? 101 VAL B CG1 1 ATOM 2333 C CG2 . VAL B 2 101 ? 102.853 16.189 -25.313 1.00 48.08 ? 101 VAL B CG2 1 ATOM 2334 N N . TYR B 2 102 ? 99.420 19.174 -25.827 1.00 54.98 ? 102 TYR B N 1 ATOM 2335 C CA . TYR B 2 102 ? 98.709 20.306 -26.410 1.00 57.86 ? 102 TYR B CA 1 ATOM 2336 C C . TYR B 2 102 ? 99.313 21.590 -25.809 1.00 64.26 ? 102 TYR B C 1 ATOM 2337 O O . TYR B 2 102 ? 99.964 21.554 -24.758 1.00 64.61 ? 102 TYR B O 1 ATOM 2338 C CB . TYR B 2 102 ? 97.216 20.223 -26.071 1.00 51.20 ? 102 TYR B CB 1 ATOM 2339 C CG . TYR B 2 102 ? 96.931 20.296 -24.585 1.00 47.96 ? 102 TYR B CG 1 ATOM 2340 C CD1 . TYR B 2 102 ? 96.382 19.216 -23.909 1.00 46.38 ? 102 TYR B CD1 1 ATOM 2341 C CD2 . TYR B 2 102 ? 97.270 21.429 -23.843 1.00 45.56 ? 102 TYR B CD2 1 ATOM 2342 C CE1 . TYR B 2 102 ? 96.189 19.265 -22.535 1.00 45.28 ? 102 TYR B CE1 1 ATOM 2343 C CE2 . TYR B 2 102 ? 97.083 21.482 -22.480 1.00 40.42 ? 102 TYR B CE2 1 ATOM 2344 C CZ . TYR B 2 102 ? 96.548 20.402 -21.833 1.00 41.23 ? 102 TYR B CZ 1 ATOM 2345 O OH . TYR B 2 102 ? 96.396 20.449 -20.476 1.00 44.43 ? 102 TYR B OH 1 ATOM 2346 N N . PRO B 2 103 ? 99.124 22.738 -26.475 1.00 69.57 ? 103 PRO B N 1 ATOM 2347 C CA . PRO B 2 103 ? 99.698 23.948 -25.889 1.00 72.77 ? 103 PRO B CA 1 ATOM 2348 C C . PRO B 2 103 ? 98.585 24.897 -25.448 1.00 77.53 ? 103 PRO B C 1 ATOM 2349 O O . PRO B 2 103 ? 97.557 24.996 -26.118 1.00 77.34 ? 103 PRO B O 1 ATOM 2350 C CB . PRO B 2 103 ? 100.488 24.513 -27.044 1.00 71.29 ? 103 PRO B CB 1 ATOM 2351 C CG . PRO B 2 103 ? 99.502 24.310 -28.182 1.00 69.75 ? 103 PRO B CG 1 ATOM 2352 C CD . PRO B 2 103 ? 98.911 22.922 -27.926 1.00 69.42 ? 103 PRO B CD 1 ATOM 2353 N N . ALA B 2 104 ? 98.775 25.574 -24.320 1.00 83.67 ? 104 ALA B N 1 ATOM 2354 C CA . ALA B 2 104 ? 97.786 26.540 -23.852 1.00 92.22 ? 104 ALA B CA 1 ATOM 2355 C C . ALA B 2 104 ? 97.875 27.665 -24.877 1.00 100.49 ? 104 ALA B C 1 ATOM 2356 O O . ALA B 2 104 ? 98.957 27.924 -25.406 1.00 102.88 ? 104 ALA B O 1 ATOM 2357 C CB . ALA B 2 104 ? 98.159 27.054 -22.480 1.00 88.90 ? 104 ALA B CB 1 ATOM 2358 N N . ARG B 2 105 ? 96.753 28.328 -25.159 1.00 107.45 ? 105 ARG B N 1 ATOM 2359 C CA . ARG B 2 105 ? 96.704 29.412 -26.151 1.00 113.43 ? 105 ARG B CA 1 ATOM 2360 C C . ARG B 2 105 ? 97.387 29.057 -27.491 1.00 116.58 ? 105 ARG B C 1 ATOM 2361 O O . ARG B 2 105 ? 98.612 28.940 -27.575 1.00 115.51 ? 105 ARG B O 1 ATOM 2362 C CB . ARG B 2 105 ? 97.296 30.714 -25.572 1.00 114.46 ? 105 ARG B CB 1 ATOM 2363 C CG . ARG B 2 105 ? 98.681 30.594 -24.938 1.00 116.64 ? 105 ARG B CG 1 ATOM 2364 C CD . ARG B 2 105 ? 99.378 31.949 -24.787 1.00 117.81 ? 105 ARG B CD 1 ATOM 2365 N NE . ARG B 2 105 ? 98.723 32.838 -23.831 1.00 117.50 ? 105 ARG B NE 1 ATOM 2366 C CZ . ARG B 2 105 ? 99.134 34.074 -23.565 1.00 117.50 ? 105 ARG B CZ 1 ATOM 2367 N NH1 . ARG B 2 105 ? 100.198 34.567 -24.185 1.00 117.30 ? 105 ARG B NH1 1 ATOM 2368 N NH2 . ARG B 2 105 ? 98.486 34.818 -22.678 1.00 116.56 ? 105 ARG B NH2 1 ATOM 2369 N N . THR B 2 106 ? 96.576 28.884 -28.534 1.00 120.83 ? 106 THR B N 1 ATOM 2370 C CA . THR B 2 106 ? 97.071 28.537 -29.868 1.00 126.19 ? 106 THR B CA 1 ATOM 2371 C C . THR B 2 106 ? 97.566 29.771 -30.603 1.00 129.19 ? 106 THR B C 1 ATOM 2372 O O . THR B 2 106 ? 98.723 29.845 -31.025 1.00 129.12 ? 106 THR B O 1 ATOM 2373 C CB . THR B 2 106 ? 95.957 27.904 -30.748 1.00 127.14 ? 106 THR B CB 1 ATOM 2374 O OG1 . THR B 2 106 ? 95.517 26.671 -30.167 1.00 130.37 ? 106 THR B OG1 1 ATOM 2375 C CG2 . THR B 2 106 ? 96.473 27.637 -32.159 1.00 125.92 ? 106 THR B CG2 1 ATOM 2376 N N . GLN B 2 107 ? 96.657 30.728 -30.761 1.00 133.55 ? 107 GLN B N 1 ATOM 2377 C CA . GLN B 2 107 ? 96.926 31.984 -31.452 1.00 137.43 ? 107 GLN B CA 1 ATOM 2378 C C . GLN B 2 107 ? 98.344 32.470 -31.166 1.00 137.85 ? 107 GLN B C 1 ATOM 2379 O O . GLN B 2 107 ? 99.015 33.023 -32.039 1.00 137.61 ? 107 GLN B O 1 ATOM 2380 C CB . GLN B 2 107 ? 95.923 33.061 -31.001 1.00 139.59 ? 107 GLN B CB 1 ATOM 2381 C CG . GLN B 2 107 ? 94.465 32.598 -30.831 1.00 140.97 ? 107 GLN B CG 1 ATOM 2382 C CD . GLN B 2 107 ? 93.749 32.327 -32.146 1.00 141.01 ? 107 GLN B CD 1 ATOM 2383 O OE1 . GLN B 2 107 ? 93.671 33.196 -33.016 1.00 140.83 ? 107 GLN B OE1 1 ATOM 2384 N NE2 . GLN B 2 107 ? 93.210 31.118 -32.289 1.00 140.54 ? 107 GLN B NE2 1 ATOM 2385 N N . THR B 2 108 ? 98.792 32.248 -29.936 1.00 138.61 ? 108 THR B N 1 ATOM 2386 C CA . THR B 2 108 ? 100.113 32.683 -29.514 1.00 139.74 ? 108 THR B CA 1 ATOM 2387 C C . THR B 2 108 ? 101.269 31.804 -29.990 1.00 140.68 ? 108 THR B C 1 ATOM 2388 O O . THR B 2 108 ? 101.789 30.980 -29.235 1.00 141.43 ? 108 THR B O 1 ATOM 2389 C CB . THR B 2 108 ? 100.182 32.804 -27.973 1.00 139.25 ? 108 THR B CB 1 ATOM 2390 O OG1 . THR B 2 108 ? 99.147 33.683 -27.511 1.00 137.90 ? 108 THR B OG1 1 ATOM 2391 C CG2 . THR B 2 108 ? 101.526 33.363 -27.545 1.00 139.13 ? 108 THR B CG2 1 ATOM 2392 N N . LEU B 2 109 ? 101.658 31.977 -31.251 1.00 141.43 ? 109 LEU B N 1 ATOM 2393 C CA . LEU B 2 109 ? 102.789 31.242 -31.813 1.00 141.25 ? 109 LEU B CA 1 ATOM 2394 C C . LEU B 2 109 ? 103.781 32.261 -32.394 1.00 139.80 ? 109 LEU B C 1 ATOM 2395 O O . LEU B 2 109 ? 104.685 31.913 -33.163 1.00 139.46 ? 109 LEU B O 1 ATOM 2396 C CB . LEU B 2 109 ? 102.327 30.215 -32.872 1.00 142.51 ? 109 LEU B CB 1 ATOM 2397 C CG . LEU B 2 109 ? 101.594 30.510 -34.192 1.00 143.21 ? 109 LEU B CG 1 ATOM 2398 C CD1 . LEU B 2 109 ? 100.310 31.277 -33.921 1.00 142.02 ? 109 LEU B CD1 1 ATOM 2399 C CD2 . LEU B 2 109 ? 102.508 31.269 -35.142 1.00 143.01 ? 109 LEU B CD2 1 ATOM 2400 N N . GLN B 2 110 ? 103.588 33.522 -31.990 1.00 137.32 ? 110 GLN B N 1 ATOM 2401 C CA . GLN B 2 110 ? 104.425 34.663 -32.387 1.00 132.93 ? 110 GLN B CA 1 ATOM 2402 C C . GLN B 2 110 ? 105.284 35.074 -31.187 1.00 130.51 ? 110 GLN B C 1 ATOM 2403 O O . GLN B 2 110 ? 106.346 35.686 -31.335 1.00 129.76 ? 110 GLN B O 1 ATOM 2404 C CB . GLN B 2 110 ? 103.563 35.872 -32.783 1.00 131.03 ? 110 GLN B CB 1 ATOM 2405 C CG . GLN B 2 110 ? 102.711 35.723 -34.032 1.00 129.46 ? 110 GLN B CG 1 ATOM 2406 C CD . GLN B 2 110 ? 101.581 34.728 -33.871 1.00 128.71 ? 110 GLN B CD 1 ATOM 2407 O OE1 . GLN B 2 110 ? 100.899 34.705 -32.846 1.00 128.38 ? 110 GLN B OE1 1 ATOM 2408 N NE2 . GLN B 2 110 ? 101.365 33.909 -34.893 1.00 127.31 ? 110 GLN B NE2 1 ATOM 2409 N N . HIS B 2 111 ? 104.796 34.737 -29.997 1.00 127.15 ? 111 HIS B N 1 ATOM 2410 C CA . HIS B 2 111 ? 105.469 35.063 -28.750 1.00 122.73 ? 111 HIS B CA 1 ATOM 2411 C C . HIS B 2 111 ? 105.355 33.928 -27.746 1.00 119.22 ? 111 HIS B C 1 ATOM 2412 O O . HIS B 2 111 ? 104.927 32.826 -28.089 1.00 118.17 ? 111 HIS B O 1 ATOM 2413 C CB . HIS B 2 111 ? 104.866 36.337 -28.165 1.00 125.35 ? 111 HIS B CB 1 ATOM 2414 C CG . HIS B 2 111 ? 103.383 36.444 -28.353 1.00 128.24 ? 111 HIS B CG 1 ATOM 2415 N ND1 . HIS B 2 111 ? 102.782 36.352 -29.591 1.00 128.93 ? 111 HIS B ND1 1 ATOM 2416 C CD2 . HIS B 2 111 ? 102.383 36.667 -27.468 1.00 129.81 ? 111 HIS B CD2 1 ATOM 2417 C CE1 . HIS B 2 111 ? 101.478 36.516 -29.461 1.00 128.99 ? 111 HIS B CE1 1 ATOM 2418 N NE2 . HIS B 2 111 ? 101.209 36.710 -28.182 1.00 130.04 ? 111 HIS B NE2 1 ATOM 2419 N N . HIS B 2 112 ? 105.734 34.211 -26.503 1.00 116.16 ? 112 HIS B N 1 ATOM 2420 C CA . HIS B 2 112 ? 105.707 33.225 -25.424 1.00 112.47 ? 112 HIS B CA 1 ATOM 2421 C C . HIS B 2 112 ? 104.456 32.342 -25.435 1.00 108.12 ? 112 HIS B C 1 ATOM 2422 O O . HIS B 2 112 ? 103.334 32.824 -25.605 1.00 107.19 ? 112 HIS B O 1 ATOM 2423 C CB . HIS B 2 112 ? 105.815 33.926 -24.068 1.00 114.26 ? 112 HIS B CB 1 ATOM 2424 C CG . HIS B 2 112 ? 104.567 34.646 -23.672 1.00 117.88 ? 112 HIS B CG 1 ATOM 2425 N ND1 . HIS B 2 112 ? 104.060 35.706 -24.393 1.00 119.63 ? 112 HIS B ND1 1 ATOM 2426 C CD2 . HIS B 2 112 ? 103.691 34.423 -22.664 1.00 119.27 ? 112 HIS B CD2 1 ATOM 2427 C CE1 . HIS B 2 112 ? 102.925 36.103 -23.848 1.00 120.38 ? 112 HIS B CE1 1 ATOM 2428 N NE2 . HIS B 2 112 ? 102.678 35.341 -22.798 1.00 121.12 ? 112 HIS B NE2 1 ATOM 2429 N N . ASN B 2 113 ? 104.664 31.043 -25.239 1.00 101.95 ? 113 ASN B N 1 ATOM 2430 C CA . ASN B 2 113 ? 103.574 30.079 -25.219 1.00 93.91 ? 113 ASN B CA 1 ATOM 2431 C C . ASN B 2 113 ? 103.821 29.077 -24.087 1.00 89.91 ? 113 ASN B C 1 ATOM 2432 O O . ASN B 2 113 ? 104.785 29.216 -23.330 1.00 89.06 ? 113 ASN B O 1 ATOM 2433 C CB . ASN B 2 113 ? 103.500 29.362 -26.569 1.00 90.79 ? 113 ASN B CB 1 ATOM 2434 C CG . ASN B 2 113 ? 102.127 28.794 -26.850 1.00 89.67 ? 113 ASN B CG 1 ATOM 2435 O OD1 . ASN B 2 113 ? 101.862 28.292 -27.939 1.00 89.77 ? 113 ASN B OD1 1 ATOM 2436 N ND2 . ASN B 2 113 ? 101.242 28.872 -25.865 1.00 87.51 ? 113 ASN B ND2 1 ATOM 2437 N N . LEU B 2 114 ? 102.951 28.077 -23.964 1.00 83.77 ? 114 LEU B N 1 ATOM 2438 C CA . LEU B 2 114 ? 103.095 27.071 -22.918 1.00 76.22 ? 114 LEU B CA 1 ATOM 2439 C C . LEU B 2 114 ? 102.663 25.710 -23.443 1.00 73.80 ? 114 LEU B C 1 ATOM 2440 O O . LEU B 2 114 ? 101.482 25.485 -23.684 1.00 73.14 ? 114 LEU B O 1 ATOM 2441 C CB . LEU B 2 114 ? 102.233 27.447 -21.719 1.00 74.25 ? 114 LEU B CB 1 ATOM 2442 C CG . LEU B 2 114 ? 102.606 26.798 -20.388 1.00 74.20 ? 114 LEU B CG 1 ATOM 2443 C CD1 . LEU B 2 114 ? 103.937 27.340 -19.905 1.00 74.70 ? 114 LEU B CD1 1 ATOM 2444 C CD2 . LEU B 2 114 ? 101.541 27.102 -19.367 1.00 74.72 ? 114 LEU B CD2 1 ATOM 2445 N N . LEU B 2 115 ? 103.619 24.808 -23.636 1.00 71.41 ? 115 LEU B N 1 ATOM 2446 C CA . LEU B 2 115 ? 103.303 23.474 -24.132 1.00 69.88 ? 115 LEU B CA 1 ATOM 2447 C C . LEU B 2 115 ? 102.960 22.595 -22.951 1.00 66.98 ? 115 LEU B C 1 ATOM 2448 O O . LEU B 2 115 ? 103.612 22.660 -21.915 1.00 65.12 ? 115 LEU B O 1 ATOM 2449 C CB . LEU B 2 115 ? 104.491 22.882 -24.891 1.00 75.13 ? 115 LEU B CB 1 ATOM 2450 C CG . LEU B 2 115 ? 104.512 23.049 -26.416 1.00 79.08 ? 115 LEU B CG 1 ATOM 2451 C CD1 . LEU B 2 115 ? 104.396 24.512 -26.799 1.00 81.53 ? 115 LEU B CD1 1 ATOM 2452 C CD2 . LEU B 2 115 ? 105.804 22.464 -26.962 1.00 80.40 ? 115 LEU B CD2 1 ATOM 2453 N N . VAL B 2 116 ? 101.946 21.759 -23.109 1.00 64.64 ? 116 VAL B N 1 ATOM 2454 C CA . VAL B 2 116 ? 101.523 20.906 -22.010 1.00 63.12 ? 116 VAL B CA 1 ATOM 2455 C C . VAL B 2 116 ? 101.517 19.400 -22.260 1.00 63.31 ? 116 VAL B C 1 ATOM 2456 O O . VAL B 2 116 ? 100.831 18.910 -23.160 1.00 64.21 ? 116 VAL B O 1 ATOM 2457 C CB . VAL B 2 116 ? 100.118 21.321 -21.538 1.00 60.07 ? 116 VAL B CB 1 ATOM 2458 C CG1 . VAL B 2 116 ? 99.573 20.317 -20.549 1.00 61.80 ? 116 VAL B CG1 1 ATOM 2459 C CG2 . VAL B 2 116 ? 100.183 22.683 -20.902 1.00 59.68 ? 116 VAL B CG2 1 ATOM 2460 N N . CYS B 2 117 ? 102.286 18.666 -21.458 1.00 61.25 ? 117 CYS B N 1 ATOM 2461 C CA . CYS B 2 117 ? 102.304 17.215 -21.578 1.00 58.46 ? 117 CYS B CA 1 ATOM 2462 C C . CYS B 2 117 ? 101.452 16.709 -20.420 1.00 58.31 ? 117 CYS B C 1 ATOM 2463 O O . CYS B 2 117 ? 101.818 16.868 -19.250 1.00 56.02 ? 117 CYS B O 1 ATOM 2464 C CB . CYS B 2 117 ? 103.719 16.661 -21.464 1.00 56.41 ? 117 CYS B CB 1 ATOM 2465 S SG . CYS B 2 117 ? 103.823 14.930 -22.015 1.00 51.23 ? 117 CYS B SG 1 ATOM 2466 N N . SER B 2 118 ? 100.311 16.111 -20.759 1.00 56.21 ? 118 SER B N 1 ATOM 2467 C CA . SER B 2 118 ? 99.366 15.611 -19.767 1.00 53.78 ? 118 SER B CA 1 ATOM 2468 C C . SER B 2 118 ? 99.295 14.091 -19.685 1.00 52.48 ? 118 SER B C 1 ATOM 2469 O O . SER B 2 118 ? 98.544 13.462 -20.431 1.00 53.28 ? 118 SER B O 1 ATOM 2470 C CB . SER B 2 118 ? 97.971 16.172 -20.071 1.00 52.08 ? 118 SER B CB 1 ATOM 2471 O OG . SER B 2 118 ? 96.971 15.552 -19.285 1.00 50.04 ? 118 SER B OG 1 ATOM 2472 N N . VAL B 2 119 ? 100.062 13.509 -18.766 1.00 50.03 ? 119 VAL B N 1 ATOM 2473 C CA . VAL B 2 119 ? 100.083 12.057 -18.572 1.00 46.96 ? 119 VAL B CA 1 ATOM 2474 C C . VAL B 2 119 ? 98.911 11.641 -17.671 1.00 42.16 ? 119 VAL B C 1 ATOM 2475 O O . VAL B 2 119 ? 98.809 12.093 -16.534 1.00 38.27 ? 119 VAL B O 1 ATOM 2476 C CB . VAL B 2 119 ? 101.409 11.619 -17.923 1.00 49.56 ? 119 VAL B CB 1 ATOM 2477 C CG1 . VAL B 2 119 ? 101.606 10.122 -18.123 1.00 52.06 ? 119 VAL B CG1 1 ATOM 2478 C CG2 . VAL B 2 119 ? 102.577 12.425 -18.510 1.00 45.66 ? 119 VAL B CG2 1 ATOM 2479 N N . ASN B 2 120 ? 98.043 10.765 -18.169 1.00 39.87 ? 120 ASN B N 1 ATOM 2480 C CA . ASN B 2 120 ? 96.861 10.364 -17.408 1.00 43.03 ? 120 ASN B CA 1 ATOM 2481 C C . ASN B 2 120 ? 96.582 8.874 -17.212 1.00 43.98 ? 120 ASN B C 1 ATOM 2482 O O . ASN B 2 120 ? 96.793 8.059 -18.110 1.00 48.93 ? 120 ASN B O 1 ATOM 2483 C CB . ASN B 2 120 ? 95.619 10.966 -18.061 1.00 45.22 ? 120 ASN B CB 1 ATOM 2484 C CG . ASN B 2 120 ? 95.715 12.461 -18.228 1.00 50.29 ? 120 ASN B CG 1 ATOM 2485 O OD1 . ASN B 2 120 ? 95.384 13.221 -17.317 1.00 53.85 ? 120 ASN B OD1 1 ATOM 2486 N ND2 . ASN B 2 120 ? 96.181 12.897 -19.398 1.00 51.01 ? 120 ASN B ND2 1 ATOM 2487 N N . GLY B 2 121 ? 96.076 8.538 -16.030 1.00 41.87 ? 121 GLY B N 1 ATOM 2488 C CA . GLY B 2 121 ? 95.694 7.170 -15.727 1.00 37.71 ? 121 GLY B CA 1 ATOM 2489 C C . GLY B 2 121 ? 96.727 6.072 -15.604 1.00 36.06 ? 121 GLY B C 1 ATOM 2490 O O . GLY B 2 121 ? 96.357 4.898 -15.570 1.00 32.34 ? 121 GLY B O 1 ATOM 2491 N N . PHE B 2 122 ? 98.004 6.429 -15.529 1.00 35.78 ? 122 PHE B N 1 ATOM 2492 C CA . PHE B 2 122 ? 99.064 5.431 -15.407 1.00 37.80 ? 122 PHE B CA 1 ATOM 2493 C C . PHE B 2 122 ? 99.112 4.967 -13.963 1.00 40.15 ? 122 PHE B C 1 ATOM 2494 O O . PHE B 2 122 ? 98.776 5.762 -13.083 1.00 38.48 ? 122 PHE B O 1 ATOM 2495 C CB . PHE B 2 122 ? 100.396 6.050 -15.825 1.00 37.05 ? 122 PHE B CB 1 ATOM 2496 C CG . PHE B 2 122 ? 100.816 7.220 -14.993 1.00 33.38 ? 122 PHE B CG 1 ATOM 2497 C CD1 . PHE B 2 122 ? 101.564 7.036 -13.838 1.00 33.06 ? 122 PHE B CD1 1 ATOM 2498 C CD2 . PHE B 2 122 ? 100.464 8.507 -15.361 1.00 33.34 ? 122 PHE B CD2 1 ATOM 2499 C CE1 . PHE B 2 122 ? 101.956 8.123 -13.060 1.00 33.06 ? 122 PHE B CE1 1 ATOM 2500 C CE2 . PHE B 2 122 ? 100.852 9.599 -14.585 1.00 32.84 ? 122 PHE B CE2 1 ATOM 2501 C CZ . PHE B 2 122 ? 101.599 9.403 -13.434 1.00 29.71 ? 122 PHE B CZ 1 ATOM 2502 N N . TYR B 2 123 ? 99.502 3.710 -13.688 1.00 44.61 ? 123 TYR B N 1 ATOM 2503 C CA . TYR B 2 123 ? 99.523 3.309 -12.275 1.00 48.60 ? 123 TYR B CA 1 ATOM 2504 C C . TYR B 2 123 ? 100.792 3.442 -11.448 1.00 48.96 ? 123 TYR B C 1 ATOM 2505 O O . TYR B 2 123 ? 100.973 4.454 -10.772 1.00 55.89 ? 123 TYR B O 1 ATOM 2506 C CB . TYR B 2 123 ? 98.957 1.903 -12.000 1.00 44.49 ? 123 TYR B CB 1 ATOM 2507 C CG . TYR B 2 123 ? 98.911 1.639 -10.478 1.00 44.37 ? 123 TYR B CG 1 ATOM 2508 C CD1 . TYR B 2 123 ? 100.022 1.124 -9.790 1.00 44.81 ? 123 TYR B CD1 1 ATOM 2509 C CD2 . TYR B 2 123 ? 97.810 2.027 -9.713 1.00 42.74 ? 123 TYR B CD2 1 ATOM 2510 C CE1 . TYR B 2 123 ? 100.040 1.016 -8.385 1.00 42.41 ? 123 TYR B CE1 1 ATOM 2511 C CE2 . TYR B 2 123 ? 97.817 1.920 -8.307 1.00 41.94 ? 123 TYR B CE2 1 ATOM 2512 C CZ . TYR B 2 123 ? 98.936 1.416 -7.647 1.00 41.62 ? 123 TYR B CZ 1 ATOM 2513 O OH . TYR B 2 123 ? 98.956 1.321 -6.260 1.00 34.03 ? 123 TYR B OH 1 ATOM 2514 N N . PRO B 2 124 ? 101.682 2.441 -11.470 1.00 44.40 ? 124 PRO B N 1 ATOM 2515 C CA . PRO B 2 124 ? 102.853 2.672 -10.616 1.00 44.59 ? 124 PRO B CA 1 ATOM 2516 C C . PRO B 2 124 ? 103.210 4.162 -10.538 1.00 47.43 ? 124 PRO B C 1 ATOM 2517 O O . PRO B 2 124 ? 103.531 4.794 -11.546 1.00 48.81 ? 124 PRO B O 1 ATOM 2518 C CB . PRO B 2 124 ? 103.918 1.808 -11.262 1.00 41.81 ? 124 PRO B CB 1 ATOM 2519 C CG . PRO B 2 124 ? 103.094 0.662 -11.793 1.00 42.47 ? 124 PRO B CG 1 ATOM 2520 C CD . PRO B 2 124 ? 101.943 1.376 -12.447 1.00 38.73 ? 124 PRO B CD 1 ATOM 2521 N N . GLY B 2 125 ? 103.083 4.730 -9.341 1.00 48.02 ? 125 GLY B N 1 ATOM 2522 C CA . GLY B 2 125 ? 103.370 6.141 -9.154 1.00 47.69 ? 125 GLY B CA 1 ATOM 2523 C C . GLY B 2 125 ? 104.605 6.592 -9.901 1.00 47.81 ? 125 GLY B C 1 ATOM 2524 O O . GLY B 2 125 ? 104.597 7.600 -10.591 1.00 48.62 ? 125 GLY B O 1 ATOM 2525 N N . SER B 2 126 ? 105.672 5.825 -9.761 1.00 50.47 ? 126 SER B N 1 ATOM 2526 C CA . SER B 2 126 ? 106.933 6.125 -10.412 1.00 54.86 ? 126 SER B CA 1 ATOM 2527 C C . SER B 2 126 ? 106.840 6.382 -11.914 1.00 54.95 ? 126 SER B C 1 ATOM 2528 O O . SER B 2 126 ? 106.427 5.513 -12.679 1.00 57.58 ? 126 SER B O 1 ATOM 2529 C CB . SER B 2 126 ? 107.911 4.979 -10.171 1.00 59.18 ? 126 SER B CB 1 ATOM 2530 O OG . SER B 2 126 ? 109.046 5.122 -11.008 1.00 67.61 ? 126 SER B OG 1 ATOM 2531 N N . ILE B 2 127 ? 107.237 7.578 -12.334 1.00 54.40 ? 127 ILE B N 1 ATOM 2532 C CA . ILE B 2 127 ? 107.231 7.935 -13.748 1.00 51.60 ? 127 ILE B CA 1 ATOM 2533 C C . ILE B 2 127 ? 108.266 9.026 -13.924 1.00 51.83 ? 127 ILE B C 1 ATOM 2534 O O . ILE B 2 127 ? 108.806 9.545 -12.951 1.00 50.45 ? 127 ILE B O 1 ATOM 2535 C CB . ILE B 2 127 ? 105.831 8.443 -14.230 1.00 49.55 ? 127 ILE B CB 1 ATOM 2536 C CG1 . ILE B 2 127 ? 105.770 8.412 -15.758 1.00 48.58 ? 127 ILE B CG1 1 ATOM 2537 C CG2 . ILE B 2 127 ? 105.574 9.865 -13.756 1.00 43.88 ? 127 ILE B CG2 1 ATOM 2538 C CD1 . ILE B 2 127 ? 104.368 8.494 -16.323 1.00 47.57 ? 127 ILE B CD1 1 ATOM 2539 N N . GLU B 2 128 ? 108.559 9.374 -15.163 1.00 52.71 ? 128 GLU B N 1 ATOM 2540 C CA . GLU B 2 128 ? 109.545 10.405 -15.393 1.00 55.83 ? 128 GLU B CA 1 ATOM 2541 C C . GLU B 2 128 ? 109.319 10.995 -16.763 1.00 54.81 ? 128 GLU B C 1 ATOM 2542 O O . GLU B 2 128 ? 109.350 10.269 -17.758 1.00 54.81 ? 128 GLU B O 1 ATOM 2543 C CB . GLU B 2 128 ? 110.929 9.796 -15.304 1.00 61.76 ? 128 GLU B CB 1 ATOM 2544 C CG . GLU B 2 128 ? 112.037 10.781 -15.490 1.00 70.89 ? 128 GLU B CG 1 ATOM 2545 C CD . GLU B 2 128 ? 113.346 10.090 -15.761 1.00 78.36 ? 128 GLU B CD 1 ATOM 2546 O OE1 . GLU B 2 128 ? 114.352 10.800 -15.958 1.00 83.77 ? 128 GLU B OE1 1 ATOM 2547 O OE2 . GLU B 2 128 ? 113.367 8.838 -15.780 1.00 81.99 ? 128 GLU B OE2 1 ATOM 2548 N N . VAL B 2 129 ? 109.095 12.308 -16.811 1.00 53.02 ? 129 VAL B N 1 ATOM 2549 C CA . VAL B 2 129 ? 108.839 12.993 -18.070 1.00 52.57 ? 129 VAL B CA 1 ATOM 2550 C C . VAL B 2 129 ? 109.992 13.918 -18.476 1.00 55.35 ? 129 VAL B C 1 ATOM 2551 O O . VAL B 2 129 ? 110.646 14.539 -17.627 1.00 54.54 ? 129 VAL B O 1 ATOM 2552 C CB . VAL B 2 129 ? 107.531 13.800 -17.986 1.00 49.72 ? 129 VAL B CB 1 ATOM 2553 C CG1 . VAL B 2 129 ? 107.047 14.158 -19.371 1.00 49.22 ? 129 VAL B CG1 1 ATOM 2554 C CG2 . VAL B 2 129 ? 106.479 12.993 -17.268 1.00 49.61 ? 129 VAL B CG2 1 ATOM 2555 N N . ARG B 2 130 ? 110.234 13.993 -19.785 1.00 56.81 ? 130 ARG B N 1 ATOM 2556 C CA . ARG B 2 130 ? 111.303 14.816 -20.344 1.00 58.14 ? 130 ARG B CA 1 ATOM 2557 C C . ARG B 2 130 ? 110.779 15.627 -21.514 1.00 57.84 ? 130 ARG B C 1 ATOM 2558 O O . ARG B 2 130 ? 110.007 15.114 -22.330 1.00 53.70 ? 130 ARG B O 1 ATOM 2559 C CB . ARG B 2 130 ? 112.428 13.930 -20.858 1.00 63.54 ? 130 ARG B CB 1 ATOM 2560 C CG . ARG B 2 130 ? 112.959 12.944 -19.853 1.00 70.73 ? 130 ARG B CG 1 ATOM 2561 C CD . ARG B 2 130 ? 113.871 11.946 -20.535 1.00 75.83 ? 130 ARG B CD 1 ATOM 2562 N NE . ARG B 2 130 ? 114.595 11.111 -19.583 1.00 81.09 ? 130 ARG B NE 1 ATOM 2563 C CZ . ARG B 2 130 ? 115.514 11.569 -18.737 1.00 84.24 ? 130 ARG B CZ 1 ATOM 2564 N NH1 . ARG B 2 130 ? 115.824 12.862 -18.720 1.00 85.59 ? 130 ARG B NH1 1 ATOM 2565 N NH2 . ARG B 2 130 ? 116.132 10.732 -17.912 1.00 85.06 ? 130 ARG B NH2 1 ATOM 2566 N N . TRP B 2 131 ? 111.214 16.886 -21.599 1.00 59.30 ? 131 TRP B N 1 ATOM 2567 C CA . TRP B 2 131 ? 110.806 17.790 -22.682 1.00 59.92 ? 131 TRP B CA 1 ATOM 2568 C C . TRP B 2 131 ? 111.961 18.011 -23.650 1.00 61.61 ? 131 TRP B C 1 ATOM 2569 O O . TRP B 2 131 ? 112.963 18.629 -23.298 1.00 62.14 ? 131 TRP B O 1 ATOM 2570 C CB . TRP B 2 131 ? 110.352 19.145 -22.123 1.00 54.68 ? 131 TRP B CB 1 ATOM 2571 C CG . TRP B 2 131 ? 108.858 19.311 -22.042 1.00 50.39 ? 131 TRP B CG 1 ATOM 2572 C CD1 . TRP B 2 131 ? 108.139 19.680 -20.947 1.00 49.83 ? 131 TRP B CD1 1 ATOM 2573 C CD2 . TRP B 2 131 ? 107.906 19.136 -23.104 1.00 47.49 ? 131 TRP B CD2 1 ATOM 2574 N NE1 . TRP B 2 131 ? 106.799 19.747 -21.256 1.00 49.28 ? 131 TRP B NE1 1 ATOM 2575 C CE2 . TRP B 2 131 ? 106.630 19.419 -22.573 1.00 46.72 ? 131 TRP B CE2 1 ATOM 2576 C CE3 . TRP B 2 131 ? 108.008 18.771 -24.449 1.00 47.17 ? 131 TRP B CE3 1 ATOM 2577 C CZ2 . TRP B 2 131 ? 105.465 19.348 -23.340 1.00 46.83 ? 131 TRP B CZ2 1 ATOM 2578 C CZ3 . TRP B 2 131 ? 106.844 18.700 -25.213 1.00 45.72 ? 131 TRP B CZ3 1 ATOM 2579 C CH2 . TRP B 2 131 ? 105.592 18.988 -24.655 1.00 44.34 ? 131 TRP B CH2 1 ATOM 2580 N N . PHE B 2 132 ? 111.809 17.516 -24.873 1.00 63.01 ? 132 PHE B N 1 ATOM 2581 C CA . PHE B 2 132 ? 112.853 17.638 -25.877 1.00 65.90 ? 132 PHE B CA 1 ATOM 2582 C C . PHE B 2 132 ? 112.612 18.675 -26.954 1.00 70.74 ? 132 PHE B C 1 ATOM 2583 O O . PHE B 2 132 ? 111.743 18.494 -27.810 1.00 69.45 ? 132 PHE B O 1 ATOM 2584 C CB . PHE B 2 132 ? 113.075 16.289 -26.553 1.00 63.03 ? 132 PHE B CB 1 ATOM 2585 C CG . PHE B 2 132 ? 113.798 15.302 -25.702 1.00 58.58 ? 132 PHE B CG 1 ATOM 2586 C CD1 . PHE B 2 132 ? 113.638 13.943 -25.917 1.00 58.33 ? 132 PHE B CD1 1 ATOM 2587 C CD2 . PHE B 2 132 ? 114.638 15.731 -24.684 1.00 55.28 ? 132 PHE B CD2 1 ATOM 2588 C CE1 . PHE B 2 132 ? 114.300 13.027 -25.128 1.00 60.54 ? 132 PHE B CE1 1 ATOM 2589 C CE2 . PHE B 2 132 ? 115.306 14.828 -23.892 1.00 55.29 ? 132 PHE B CE2 1 ATOM 2590 C CZ . PHE B 2 132 ? 115.139 13.473 -24.108 1.00 60.14 ? 132 PHE B CZ 1 ATOM 2591 N N . ARG B 2 133 ? 113.391 19.754 -26.917 1.00 75.94 ? 133 ARG B N 1 ATOM 2592 C CA . ARG B 2 133 ? 113.287 20.795 -27.931 1.00 82.66 ? 133 ARG B CA 1 ATOM 2593 C C . ARG B 2 133 ? 114.269 20.395 -29.037 1.00 85.33 ? 133 ARG B C 1 ATOM 2594 O O . ARG B 2 133 ? 115.488 20.546 -28.887 1.00 84.24 ? 133 ARG B O 1 ATOM 2595 C CB . ARG B 2 133 ? 113.673 22.160 -27.360 1.00 86.59 ? 133 ARG B CB 1 ATOM 2596 C CG . ARG B 2 133 ? 113.368 23.318 -28.311 1.00 91.50 ? 133 ARG B CG 1 ATOM 2597 C CD . ARG B 2 133 ? 113.897 24.646 -27.790 1.00 93.74 ? 133 ARG B CD 1 ATOM 2598 N NE . ARG B 2 133 ? 115.356 24.666 -27.749 1.00 97.79 ? 133 ARG B NE 1 ATOM 2599 C CZ . ARG B 2 133 ? 116.138 24.496 -28.812 1.00 100.57 ? 133 ARG B CZ 1 ATOM 2600 N NH1 . ARG B 2 133 ? 115.600 24.292 -30.009 1.00 99.87 ? 133 ARG B NH1 1 ATOM 2601 N NH2 . ARG B 2 133 ? 117.461 24.532 -28.683 1.00 101.84 ? 133 ARG B NH2 1 ATOM 2602 N N . ASN B 2 134 ? 113.729 19.882 -30.142 1.00 88.17 ? 134 ASN B N 1 ATOM 2603 C CA . ASN B 2 134 ? 114.542 19.419 -31.263 1.00 89.77 ? 134 ASN B CA 1 ATOM 2604 C C . ASN B 2 134 ? 115.548 18.428 -30.727 1.00 89.64 ? 134 ASN B C 1 ATOM 2605 O O . ASN B 2 134 ? 116.748 18.698 -30.702 1.00 89.89 ? 134 ASN B O 1 ATOM 2606 C CB . ASN B 2 134 ? 115.276 20.577 -31.938 1.00 92.68 ? 134 ASN B CB 1 ATOM 2607 C CG . ASN B 2 134 ? 114.371 21.389 -32.835 1.00 97.22 ? 134 ASN B CG 1 ATOM 2608 O OD1 . ASN B 2 134 ? 113.623 20.834 -33.642 1.00 97.89 ? 134 ASN B OD1 1 ATOM 2609 N ND2 . ASN B 2 134 ? 114.439 22.711 -32.708 1.00 101.03 ? 134 ASN B ND2 1 ATOM 2610 N N . SER B 2 135 ? 115.040 17.283 -30.286 1.00 90.28 ? 135 SER B N 1 ATOM 2611 C CA . SER B 2 135 ? 115.875 16.231 -29.729 1.00 91.71 ? 135 SER B CA 1 ATOM 2612 C C . SER B 2 135 ? 117.044 16.854 -28.955 1.00 91.88 ? 135 SER B C 1 ATOM 2613 O O . SER B 2 135 ? 118.199 16.816 -29.384 1.00 91.38 ? 135 SER B O 1 ATOM 2614 C CB . SER B 2 135 ? 116.369 15.317 -30.855 1.00 92.75 ? 135 SER B CB 1 ATOM 2615 O OG . SER B 2 135 ? 115.273 14.730 -31.549 1.00 91.11 ? 135 SER B OG 1 ATOM 2616 N N . GLN B 2 136 ? 116.708 17.446 -27.813 1.00 91.89 ? 136 GLN B N 1 ATOM 2617 C CA . GLN B 2 136 ? 117.672 18.103 -26.941 1.00 91.00 ? 136 GLN B CA 1 ATOM 2618 C C . GLN B 2 136 ? 116.951 18.446 -25.637 1.00 88.85 ? 136 GLN B C 1 ATOM 2619 O O . GLN B 2 136 ? 116.061 19.297 -25.612 1.00 86.93 ? 136 GLN B O 1 ATOM 2620 C CB . GLN B 2 136 ? 118.201 19.368 -27.622 1.00 94.45 ? 136 GLN B CB 1 ATOM 2621 C CG . GLN B 2 136 ? 119.244 20.139 -26.834 1.00 98.06 ? 136 GLN B CG 1 ATOM 2622 C CD . GLN B 2 136 ? 118.723 21.477 -26.342 1.00 101.35 ? 136 GLN B CD 1 ATOM 2623 O OE1 . GLN B 2 136 ? 117.878 21.537 -25.448 1.00 103.52 ? 136 GLN B OE1 1 ATOM 2624 N NE2 . GLN B 2 136 ? 119.218 22.560 -26.935 1.00 101.35 ? 136 GLN B NE2 1 ATOM 2625 N N . GLU B 2 137 ? 117.336 17.758 -24.566 1.00 87.97 ? 137 GLU B N 1 ATOM 2626 C CA . GLU B 2 137 ? 116.747 17.942 -23.241 1.00 87.00 ? 137 GLU B CA 1 ATOM 2627 C C . GLU B 2 137 ? 116.512 19.409 -22.896 1.00 84.95 ? 137 GLU B C 1 ATOM 2628 O O . GLU B 2 137 ? 117.408 20.243 -23.019 1.00 83.48 ? 137 GLU B O 1 ATOM 2629 C CB . GLU B 2 137 ? 117.647 17.296 -22.178 1.00 88.93 ? 137 GLU B CB 1 ATOM 2630 C CG . GLU B 2 137 ? 117.153 17.406 -20.730 1.00 92.73 ? 137 GLU B CG 1 ATOM 2631 C CD . GLU B 2 137 ? 116.105 16.363 -20.353 1.00 94.99 ? 137 GLU B CD 1 ATOM 2632 O OE1 . GLU B 2 137 ? 114.959 16.449 -20.849 1.00 97.70 ? 137 GLU B OE1 1 ATOM 2633 O OE2 . GLU B 2 137 ? 116.433 15.455 -19.555 1.00 93.38 ? 137 GLU B OE2 1 ATOM 2634 N N . GLU B 2 138 ? 115.292 19.713 -22.467 1.00 83.41 ? 138 GLU B N 1 ATOM 2635 C CA . GLU B 2 138 ? 114.932 21.070 -22.100 1.00 80.82 ? 138 GLU B CA 1 ATOM 2636 C C . GLU B 2 138 ? 115.149 21.186 -20.611 1.00 79.41 ? 138 GLU B C 1 ATOM 2637 O O . GLU B 2 138 ? 114.277 21.627 -19.876 1.00 79.21 ? 138 GLU B O 1 ATOM 2638 C CB . GLU B 2 138 ? 113.471 21.347 -22.448 1.00 80.65 ? 138 GLU B CB 1 ATOM 2639 C CG . GLU B 2 138 ? 113.145 22.819 -22.597 1.00 81.01 ? 138 GLU B CG 1 ATOM 2640 C CD . GLU B 2 138 ? 114.058 23.512 -23.588 1.00 81.14 ? 138 GLU B CD 1 ATOM 2641 O OE1 . GLU B 2 138 ? 115.222 23.782 -23.225 1.00 82.85 ? 138 GLU B OE1 1 ATOM 2642 O OE2 . GLU B 2 138 ? 113.621 23.774 -24.729 1.00 77.55 ? 138 GLU B OE2 1 ATOM 2643 N N . LYS B 2 139 ? 116.336 20.769 -20.193 1.00 80.50 ? 139 LYS B N 1 ATOM 2644 C CA . LYS B 2 139 ? 116.784 20.776 -18.801 1.00 83.31 ? 139 LYS B CA 1 ATOM 2645 C C . LYS B 2 139 ? 116.244 21.840 -17.829 1.00 82.57 ? 139 LYS B C 1 ATOM 2646 O O . LYS B 2 139 ? 116.401 21.690 -16.610 1.00 81.38 ? 139 LYS B O 1 ATOM 2647 C CB . LYS B 2 139 ? 118.325 20.792 -18.771 1.00 87.08 ? 139 LYS B CB 1 ATOM 2648 C CG . LYS B 2 139 ? 119.028 21.500 -19.964 1.00 89.36 ? 139 LYS B CG 1 ATOM 2649 C CD . LYS B 2 139 ? 118.688 22.996 -20.106 1.00 89.19 ? 139 LYS B CD 1 ATOM 2650 C CE . LYS B 2 139 ? 117.474 23.235 -21.010 1.00 88.42 ? 139 LYS B CE 1 ATOM 2651 N NZ . LYS B 2 139 ? 117.046 24.661 -21.068 1.00 85.27 ? 139 LYS B NZ 1 ATOM 2652 N N . ALA B 2 140 ? 115.630 22.905 -18.349 1.00 81.82 ? 140 ALA B N 1 ATOM 2653 C CA . ALA B 2 140 ? 115.072 23.969 -17.503 1.00 79.73 ? 140 ALA B CA 1 ATOM 2654 C C . ALA B 2 140 ? 113.918 24.719 -18.171 1.00 78.13 ? 140 ALA B C 1 ATOM 2655 O O . ALA B 2 140 ? 113.587 24.472 -19.337 1.00 77.70 ? 140 ALA B O 1 ATOM 2656 C CB . ALA B 2 140 ? 116.165 24.952 -17.101 1.00 79.11 ? 140 ALA B CB 1 ATOM 2657 N N . GLY B 2 141 ? 113.313 25.641 -17.427 1.00 75.37 ? 141 GLY B N 1 ATOM 2658 C CA . GLY B 2 141 ? 112.195 26.390 -17.965 1.00 73.76 ? 141 GLY B CA 1 ATOM 2659 C C . GLY B 2 141 ? 111.021 25.445 -18.117 1.00 73.58 ? 141 GLY B C 1 ATOM 2660 O O . GLY B 2 141 ? 110.190 25.580 -19.020 1.00 72.36 ? 141 GLY B O 1 ATOM 2661 N N . VAL B 2 142 ? 110.967 24.463 -17.224 1.00 73.47 ? 142 VAL B N 1 ATOM 2662 C CA . VAL B 2 142 ? 109.897 23.480 -17.238 1.00 71.01 ? 142 VAL B CA 1 ATOM 2663 C C . VAL B 2 142 ? 109.143 23.499 -15.923 1.00 68.35 ? 142 VAL B C 1 ATOM 2664 O O . VAL B 2 142 ? 109.752 23.541 -14.853 1.00 66.07 ? 142 VAL B O 1 ATOM 2665 C CB . VAL B 2 142 ? 110.442 22.073 -17.470 1.00 71.27 ? 142 VAL B CB 1 ATOM 2666 C CG1 . VAL B 2 142 ? 109.301 21.064 -17.438 1.00 71.18 ? 142 VAL B CG1 1 ATOM 2667 C CG2 . VAL B 2 142 ? 111.156 22.024 -18.805 1.00 72.51 ? 142 VAL B CG2 1 ATOM 2668 N N . VAL B 2 143 ? 107.815 23.472 -16.015 1.00 65.75 ? 143 VAL B N 1 ATOM 2669 C CA . VAL B 2 143 ? 106.968 23.493 -14.832 1.00 64.59 ? 143 VAL B CA 1 ATOM 2670 C C . VAL B 2 143 ? 106.043 22.282 -14.758 1.00 61.26 ? 143 VAL B C 1 ATOM 2671 O O . VAL B 2 143 ? 105.272 22.006 -15.681 1.00 58.06 ? 143 VAL B O 1 ATOM 2672 C CB . VAL B 2 143 ? 106.150 24.793 -14.768 1.00 66.61 ? 143 VAL B CB 1 ATOM 2673 C CG1 . VAL B 2 143 ? 105.222 24.772 -13.571 1.00 69.58 ? 143 VAL B CG1 1 ATOM 2674 C CG2 . VAL B 2 143 ? 107.095 25.971 -14.642 1.00 67.95 ? 143 VAL B CG2 1 ATOM 2675 N N . SER B 2 144 ? 106.138 21.584 -13.625 1.00 58.19 ? 144 SER B N 1 ATOM 2676 C CA . SER B 2 144 ? 105.389 20.366 -13.340 1.00 53.88 ? 144 SER B CA 1 ATOM 2677 C C . SER B 2 144 ? 104.367 20.484 -12.215 1.00 50.25 ? 144 SER B C 1 ATOM 2678 O O . SER B 2 144 ? 104.551 21.244 -11.265 1.00 46.88 ? 144 SER B O 1 ATOM 2679 C CB . SER B 2 144 ? 106.376 19.247 -12.993 1.00 59.18 ? 144 SER B CB 1 ATOM 2680 O OG . SER B 2 144 ? 105.738 18.156 -12.346 1.00 63.49 ? 144 SER B OG 1 ATOM 2681 N N . THR B 2 145 ? 103.303 19.692 -12.339 1.00 48.48 ? 145 THR B N 1 ATOM 2682 C CA . THR B 2 145 ? 102.200 19.631 -11.376 1.00 44.09 ? 145 THR B CA 1 ATOM 2683 C C . THR B 2 145 ? 102.575 18.731 -10.214 1.00 42.35 ? 145 THR B C 1 ATOM 2684 O O . THR B 2 145 ? 101.959 18.780 -9.160 1.00 41.55 ? 145 THR B O 1 ATOM 2685 C CB . THR B 2 145 ? 100.933 19.006 -12.007 1.00 42.97 ? 145 THR B CB 1 ATOM 2686 O OG1 . THR B 2 145 ? 101.248 17.702 -12.514 1.00 41.19 ? 145 THR B OG1 1 ATOM 2687 C CG2 . THR B 2 145 ? 100.418 19.849 -13.147 1.00 44.55 ? 145 THR B CG2 1 ATOM 2688 N N . GLY B 2 146 ? 103.592 17.906 -10.424 1.00 41.73 ? 146 GLY B N 1 ATOM 2689 C CA . GLY B 2 146 ? 104.003 16.965 -9.406 1.00 38.46 ? 146 GLY B CA 1 ATOM 2690 C C . GLY B 2 146 ? 103.196 15.720 -9.699 1.00 36.77 ? 146 GLY B C 1 ATOM 2691 O O . GLY B 2 146 ? 102.561 15.617 -10.749 1.00 35.31 ? 146 GLY B O 1 ATOM 2692 N N . LEU B 2 147 ? 103.200 14.765 -8.786 1.00 36.23 ? 147 LEU B N 1 ATOM 2693 C CA . LEU B 2 147 ? 102.438 13.554 -9.020 1.00 35.18 ? 147 LEU B CA 1 ATOM 2694 C C . LEU B 2 147 ? 101.070 13.749 -8.390 1.00 32.39 ? 147 LEU B C 1 ATOM 2695 O O . LEU B 2 147 ? 100.950 14.271 -7.281 1.00 30.66 ? 147 LEU B O 1 ATOM 2696 C CB . LEU B 2 147 ? 103.159 12.363 -8.395 1.00 38.90 ? 147 LEU B CB 1 ATOM 2697 C CG . LEU B 2 147 ? 102.841 10.983 -8.962 1.00 37.47 ? 147 LEU B CG 1 ATOM 2698 C CD1 . LEU B 2 147 ? 103.086 10.968 -10.459 1.00 35.96 ? 147 LEU B CD1 1 ATOM 2699 C CD2 . LEU B 2 147 ? 103.712 9.958 -8.260 1.00 38.77 ? 147 LEU B CD2 1 ATOM 2700 N N . ILE B 2 148 ? 100.035 13.333 -9.102 1.00 29.35 ? 148 ILE B N 1 ATOM 2701 C CA . ILE B 2 148 ? 98.680 13.497 -8.602 1.00 27.63 ? 148 ILE B CA 1 ATOM 2702 C C . ILE B 2 148 ? 97.921 12.181 -8.485 1.00 27.97 ? 148 ILE B C 1 ATOM 2703 O O . ILE B 2 148 ? 97.754 11.452 -9.464 1.00 28.76 ? 148 ILE B O 1 ATOM 2704 C CB . ILE B 2 148 ? 97.904 14.460 -9.513 1.00 25.97 ? 148 ILE B CB 1 ATOM 2705 C CG1 . ILE B 2 148 ? 98.528 15.847 -9.419 1.00 27.18 ? 148 ILE B CG1 1 ATOM 2706 C CG2 . ILE B 2 148 ? 96.444 14.514 -9.130 1.00 19.68 ? 148 ILE B CG2 1 ATOM 2707 C CD1 . ILE B 2 148 ? 98.073 16.776 -10.517 1.00 31.35 ? 148 ILE B CD1 1 ATOM 2708 N N . GLN B 2 149 ? 97.463 11.893 -7.273 1.00 24.97 ? 149 GLN B N 1 ATOM 2709 C CA . GLN B 2 149 ? 96.707 10.683 -6.978 1.00 26.10 ? 149 GLN B CA 1 ATOM 2710 C C . GLN B 2 149 ? 95.203 10.896 -7.215 1.00 23.96 ? 149 GLN B C 1 ATOM 2711 O O . GLN B 2 149 ? 94.586 11.736 -6.566 1.00 26.98 ? 149 GLN B O 1 ATOM 2712 C CB . GLN B 2 149 ? 96.984 10.299 -5.530 1.00 29.06 ? 149 GLN B CB 1 ATOM 2713 C CG . GLN B 2 149 ? 96.063 9.278 -4.902 1.00 36.99 ? 149 GLN B CG 1 ATOM 2714 C CD . GLN B 2 149 ? 96.553 8.901 -3.517 1.00 42.45 ? 149 GLN B CD 1 ATOM 2715 O OE1 . GLN B 2 149 ? 97.655 8.360 -3.377 1.00 45.02 ? 149 GLN B OE1 1 ATOM 2716 N NE2 . GLN B 2 149 ? 95.755 9.203 -2.485 1.00 36.99 ? 149 GLN B NE2 1 ATOM 2717 N N . ASN B 2 150 ? 94.615 10.147 -8.144 1.00 20.82 ? 150 ASN B N 1 ATOM 2718 C CA . ASN B 2 150 ? 93.197 10.303 -8.432 1.00 20.20 ? 150 ASN B CA 1 ATOM 2719 C C . ASN B 2 150 ? 92.291 9.578 -7.438 1.00 22.43 ? 150 ASN B C 1 ATOM 2720 O O . ASN B 2 150 ? 91.072 9.778 -7.427 1.00 13.77 ? 150 ASN B O 1 ATOM 2721 C CB . ASN B 2 150 ? 92.891 9.835 -9.850 1.00 22.25 ? 150 ASN B CB 1 ATOM 2722 C CG . ASN B 2 150 ? 93.574 10.681 -10.899 1.00 22.20 ? 150 ASN B CG 1 ATOM 2723 O OD1 . ASN B 2 150 ? 93.782 11.867 -10.698 1.00 19.67 ? 150 ASN B OD1 1 ATOM 2724 N ND2 . ASN B 2 150 ? 93.913 10.076 -12.033 1.00 25.89 ? 150 ASN B ND2 1 ATOM 2725 N N . GLY B 2 151 ? 92.894 8.740 -6.599 1.00 26.67 ? 151 GLY B N 1 ATOM 2726 C CA . GLY B 2 151 ? 92.129 8.013 -5.601 1.00 30.37 ? 151 GLY B CA 1 ATOM 2727 C C . GLY B 2 151 ? 91.500 6.728 -6.110 1.00 33.87 ? 151 GLY B C 1 ATOM 2728 O O . GLY B 2 151 ? 90.816 6.019 -5.367 1.00 32.68 ? 151 GLY B O 1 ATOM 2729 N N . ASP B 2 152 ? 91.723 6.416 -7.380 1.00 35.61 ? 152 ASP B N 1 ATOM 2730 C CA . ASP B 2 152 ? 91.156 5.205 -7.942 1.00 37.85 ? 152 ASP B CA 1 ATOM 2731 C C . ASP B 2 152 ? 92.243 4.274 -8.447 1.00 39.43 ? 152 ASP B C 1 ATOM 2732 O O . ASP B 2 152 ? 92.064 3.566 -9.436 1.00 37.47 ? 152 ASP B O 1 ATOM 2733 C CB . ASP B 2 152 ? 90.180 5.543 -9.072 1.00 42.37 ? 152 ASP B CB 1 ATOM 2734 C CG . ASP B 2 152 ? 90.848 6.254 -10.230 1.00 46.58 ? 152 ASP B CG 1 ATOM 2735 O OD1 . ASP B 2 152 ? 92.067 6.528 -10.117 1.00 47.97 ? 152 ASP B OD1 1 ATOM 2736 O OD2 . ASP B 2 152 ? 90.152 6.536 -11.244 1.00 44.23 ? 152 ASP B OD2 1 ATOM 2737 N N . TRP B 2 153 ? 93.379 4.271 -7.759 1.00 42.71 ? 153 TRP B N 1 ATOM 2738 C CA . TRP B 2 153 ? 94.477 3.400 -8.151 1.00 43.06 ? 153 TRP B CA 1 ATOM 2739 C C . TRP B 2 153 ? 94.997 3.767 -9.526 1.00 43.41 ? 153 TRP B C 1 ATOM 2740 O O . TRP B 2 153 ? 95.095 2.912 -10.414 1.00 43.65 ? 153 TRP B O 1 ATOM 2741 C CB . TRP B 2 153 ? 94.019 1.945 -8.174 1.00 40.91 ? 153 TRP B CB 1 ATOM 2742 C CG . TRP B 2 153 ? 93.844 1.360 -6.831 1.00 36.34 ? 153 TRP B CG 1 ATOM 2743 C CD1 . TRP B 2 153 ? 92.783 1.513 -5.999 1.00 34.64 ? 153 TRP B CD1 1 ATOM 2744 C CD2 . TRP B 2 153 ? 94.776 0.531 -6.151 1.00 32.75 ? 153 TRP B CD2 1 ATOM 2745 N NE1 . TRP B 2 153 ? 92.995 0.826 -4.836 1.00 33.00 ? 153 TRP B NE1 1 ATOM 2746 C CE2 . TRP B 2 153 ? 94.215 0.212 -4.906 1.00 32.06 ? 153 TRP B CE2 1 ATOM 2747 C CE3 . TRP B 2 153 ? 96.038 0.027 -6.476 1.00 31.14 ? 153 TRP B CE3 1 ATOM 2748 C CZ2 . TRP B 2 153 ? 94.867 -0.589 -3.984 1.00 35.16 ? 153 TRP B CZ2 1 ATOM 2749 C CZ3 . TRP B 2 153 ? 96.689 -0.764 -5.564 1.00 31.30 ? 153 TRP B CZ3 1 ATOM 2750 C CH2 . TRP B 2 153 ? 96.105 -1.067 -4.330 1.00 35.92 ? 153 TRP B CH2 1 ATOM 2751 N N . THR B 2 154 ? 95.303 5.047 -9.696 1.00 40.85 ? 154 THR B N 1 ATOM 2752 C CA . THR B 2 154 ? 95.832 5.574 -10.943 1.00 33.31 ? 154 THR B CA 1 ATOM 2753 C C . THR B 2 154 ? 96.306 6.949 -10.575 1.00 33.27 ? 154 THR B C 1 ATOM 2754 O O . THR B 2 154 ? 95.860 7.519 -9.577 1.00 34.02 ? 154 THR B O 1 ATOM 2755 C CB . THR B 2 154 ? 94.762 5.788 -12.019 1.00 29.09 ? 154 THR B CB 1 ATOM 2756 O OG1 . THR B 2 154 ? 93.991 6.943 -11.678 1.00 20.22 ? 154 THR B OG1 1 ATOM 2757 C CG2 . THR B 2 154 ? 93.853 4.587 -12.146 1.00 23.71 ? 154 THR B CG2 1 ATOM 2758 N N . PHE B 2 155 ? 97.202 7.482 -11.387 1.00 31.46 ? 155 PHE B N 1 ATOM 2759 C CA . PHE B 2 155 ? 97.718 8.812 -11.154 1.00 32.02 ? 155 PHE B CA 1 ATOM 2760 C C . PHE B 2 155 ? 97.621 9.595 -12.445 1.00 32.36 ? 155 PHE B C 1 ATOM 2761 O O . PHE B 2 155 ? 97.186 9.084 -13.479 1.00 31.17 ? 155 PHE B O 1 ATOM 2762 C CB . PHE B 2 155 ? 99.190 8.775 -10.745 1.00 32.49 ? 155 PHE B CB 1 ATOM 2763 C CG . PHE B 2 155 ? 99.463 8.039 -9.474 1.00 30.84 ? 155 PHE B CG 1 ATOM 2764 C CD1 . PHE B 2 155 ? 99.122 6.702 -9.335 1.00 34.47 ? 155 PHE B CD1 1 ATOM 2765 C CD2 . PHE B 2 155 ? 100.137 8.662 -8.441 1.00 30.70 ? 155 PHE B CD2 1 ATOM 2766 C CE1 . PHE B 2 155 ? 99.457 5.994 -8.182 1.00 34.85 ? 155 PHE B CE1 1 ATOM 2767 C CE2 . PHE B 2 155 ? 100.475 7.965 -7.288 1.00 34.71 ? 155 PHE B CE2 1 ATOM 2768 C CZ . PHE B 2 155 ? 100.136 6.628 -7.160 1.00 34.37 ? 155 PHE B CZ 1 ATOM 2769 N N . GLN B 2 156 ? 98.030 10.853 -12.359 1.00 33.68 ? 156 GLN B N 1 ATOM 2770 C CA . GLN B 2 156 ? 98.074 11.754 -13.496 1.00 33.48 ? 156 GLN B CA 1 ATOM 2771 C C . GLN B 2 156 ? 99.105 12.799 -13.114 1.00 31.79 ? 156 GLN B C 1 ATOM 2772 O O . GLN B 2 156 ? 99.423 12.971 -11.931 1.00 29.48 ? 156 GLN B O 1 ATOM 2773 C CB . GLN B 2 156 ? 96.706 12.400 -13.788 1.00 32.02 ? 156 GLN B CB 1 ATOM 2774 C CG . GLN B 2 156 ? 96.186 13.394 -12.768 1.00 31.75 ? 156 GLN B CG 1 ATOM 2775 C CD . GLN B 2 156 ? 95.016 14.208 -13.313 1.00 35.68 ? 156 GLN B CD 1 ATOM 2776 O OE1 . GLN B 2 156 ? 95.192 15.065 -14.180 1.00 36.66 ? 156 GLN B OE1 1 ATOM 2777 N NE2 . GLN B 2 156 ? 93.814 13.930 -12.818 1.00 36.50 ? 156 GLN B NE2 1 ATOM 2778 N N . THR B 2 157 ? 99.656 13.469 -14.114 1.00 30.16 ? 157 THR B N 1 ATOM 2779 C CA . THR B 2 157 ? 100.657 14.480 -13.860 1.00 29.51 ? 157 THR B CA 1 ATOM 2780 C C . THR B 2 157 ? 100.763 15.344 -15.079 1.00 32.55 ? 157 THR B C 1 ATOM 2781 O O . THR B 2 157 ? 100.518 14.879 -16.188 1.00 35.70 ? 157 THR B O 1 ATOM 2782 C CB . THR B 2 157 ? 102.005 13.862 -13.635 1.00 26.50 ? 157 THR B CB 1 ATOM 2783 O OG1 . THR B 2 157 ? 102.936 14.888 -13.288 1.00 27.54 ? 157 THR B OG1 1 ATOM 2784 C CG2 . THR B 2 157 ? 102.472 13.166 -14.905 1.00 23.73 ? 157 THR B CG2 1 ATOM 2785 N N . LEU B 2 158 ? 101.130 16.602 -14.887 1.00 35.35 ? 158 LEU B N 1 ATOM 2786 C CA . LEU B 2 158 ? 101.263 17.487 -16.025 1.00 39.44 ? 158 LEU B CA 1 ATOM 2787 C C . LEU B 2 158 ? 102.551 18.254 -15.999 1.00 41.69 ? 158 LEU B C 1 ATOM 2788 O O . LEU B 2 158 ? 102.834 18.984 -15.054 1.00 40.01 ? 158 LEU B O 1 ATOM 2789 C CB . LEU B 2 158 ? 100.085 18.455 -16.111 1.00 39.81 ? 158 LEU B CB 1 ATOM 2790 C CG . LEU B 2 158 ? 98.807 17.744 -16.568 1.00 42.10 ? 158 LEU B CG 1 ATOM 2791 C CD1 . LEU B 2 158 ? 98.097 17.150 -15.357 1.00 41.37 ? 158 LEU B CD1 1 ATOM 2792 C CD2 . LEU B 2 158 ? 97.904 18.718 -17.307 1.00 39.90 ? 158 LEU B CD2 1 ATOM 2793 N N . VAL B 2 159 ? 103.343 18.059 -17.046 1.00 46.64 ? 159 VAL B N 1 ATOM 2794 C CA . VAL B 2 159 ? 104.613 18.748 -17.179 1.00 49.58 ? 159 VAL B CA 1 ATOM 2795 C C . VAL B 2 159 ? 104.474 19.659 -18.382 1.00 52.94 ? 159 VAL B C 1 ATOM 2796 O O . VAL B 2 159 ? 104.189 19.208 -19.501 1.00 49.52 ? 159 VAL B O 1 ATOM 2797 C CB . VAL B 2 159 ? 105.779 17.782 -17.419 1.00 49.68 ? 159 VAL B CB 1 ATOM 2798 C CG1 . VAL B 2 159 ? 107.093 18.509 -17.164 1.00 49.56 ? 159 VAL B CG1 1 ATOM 2799 C CG2 . VAL B 2 159 ? 105.643 16.554 -16.524 1.00 48.30 ? 159 VAL B CG2 1 ATOM 2800 N N . MET B 2 160 ? 104.663 20.950 -18.130 1.00 58.44 ? 160 MET B N 1 ATOM 2801 C CA . MET B 2 160 ? 104.545 21.962 -19.163 1.00 62.32 ? 160 MET B CA 1 ATOM 2802 C C . MET B 2 160 ? 105.869 22.642 -19.477 1.00 64.93 ? 160 MET B C 1 ATOM 2803 O O . MET B 2 160 ? 106.721 22.845 -18.599 1.00 64.14 ? 160 MET B O 1 ATOM 2804 C CB . MET B 2 160 ? 103.546 23.032 -18.739 1.00 62.72 ? 160 MET B CB 1 ATOM 2805 C CG . MET B 2 160 ? 102.184 22.527 -18.355 1.00 58.61 ? 160 MET B CG 1 ATOM 2806 S SD . MET B 2 160 ? 101.330 23.892 -17.591 1.00 57.60 ? 160 MET B SD 1 ATOM 2807 C CE . MET B 2 160 ? 102.288 24.055 -16.050 1.00 54.12 ? 160 MET B CE 1 ATOM 2808 N N . LEU B 2 161 ? 106.005 23.013 -20.746 1.00 66.92 ? 161 LEU B N 1 ATOM 2809 C CA . LEU B 2 161 ? 107.189 23.680 -21.252 1.00 66.11 ? 161 LEU B CA 1 ATOM 2810 C C . LEU B 2 161 ? 106.809 25.066 -21.754 1.00 67.49 ? 161 LEU B C 1 ATOM 2811 O O . LEU B 2 161 ? 105.965 25.197 -22.650 1.00 64.67 ? 161 LEU B O 1 ATOM 2812 C CB . LEU B 2 161 ? 107.770 22.884 -22.416 1.00 64.27 ? 161 LEU B CB 1 ATOM 2813 C CG . LEU B 2 161 ? 109.272 22.647 -22.390 1.00 62.98 ? 161 LEU B CG 1 ATOM 2814 C CD1 . LEU B 2 161 ? 109.745 22.365 -23.811 1.00 61.10 ? 161 LEU B CD1 1 ATOM 2815 C CD2 . LEU B 2 161 ? 109.977 23.861 -21.804 1.00 64.65 ? 161 LEU B CD2 1 ATOM 2816 N N . GLU B 2 162 ? 107.405 26.099 -21.164 1.00 69.02 ? 162 GLU B N 1 ATOM 2817 C CA . GLU B 2 162 ? 107.138 27.460 -21.619 1.00 71.32 ? 162 GLU B CA 1 ATOM 2818 C C . GLU B 2 162 ? 108.265 27.790 -22.584 1.00 74.72 ? 162 GLU B C 1 ATOM 2819 O O . GLU B 2 162 ? 109.435 27.786 -22.202 1.00 74.45 ? 162 GLU B O 1 ATOM 2820 C CB . GLU B 2 162 ? 107.101 28.452 -20.447 1.00 63.68 ? 162 GLU B CB 1 ATOM 2821 C CG . GLU B 2 162 ? 108.125 28.210 -19.374 1.00 56.44 ? 162 GLU B CG 1 ATOM 2822 C CD . GLU B 2 162 ? 107.869 29.055 -18.144 1.00 53.27 ? 162 GLU B CD 1 ATOM 2823 O OE1 . GLU B 2 162 ? 106.731 29.026 -17.638 1.00 48.35 ? 162 GLU B OE1 1 ATOM 2824 O OE2 . GLU B 2 162 ? 108.801 29.743 -17.676 1.00 52.97 ? 162 GLU B OE2 1 ATOM 2825 N N . THR B 2 163 ? 107.909 28.041 -23.842 1.00 79.34 ? 163 THR B N 1 ATOM 2826 C CA . THR B 2 163 ? 108.897 28.336 -24.876 1.00 84.51 ? 163 THR B CA 1 ATOM 2827 C C . THR B 2 163 ? 108.357 29.209 -25.997 1.00 87.48 ? 163 THR B C 1 ATOM 2828 O O . THR B 2 163 ? 107.143 29.297 -26.200 1.00 89.20 ? 163 THR B O 1 ATOM 2829 C CB . THR B 2 163 ? 109.392 27.049 -25.552 1.00 85.55 ? 163 THR B CB 1 ATOM 2830 O OG1 . THR B 2 163 ? 108.300 26.435 -26.255 1.00 84.02 ? 163 THR B OG1 1 ATOM 2831 C CG2 . THR B 2 163 ? 109.947 26.082 -24.522 1.00 86.96 ? 163 THR B CG2 1 ATOM 2832 N N . VAL B 2 164 ? 109.277 29.838 -26.728 1.00 89.07 ? 164 VAL B N 1 ATOM 2833 C CA . VAL B 2 164 ? 108.931 30.670 -27.874 1.00 89.18 ? 164 VAL B CA 1 ATOM 2834 C C . VAL B 2 164 ? 108.919 29.748 -29.100 1.00 92.84 ? 164 VAL B C 1 ATOM 2835 O O . VAL B 2 164 ? 109.964 29.332 -29.605 1.00 91.38 ? 164 VAL B O 1 ATOM 2836 C CB . VAL B 2 164 ? 109.946 31.808 -28.057 1.00 84.32 ? 164 VAL B CB 1 ATOM 2837 C CG1 . VAL B 2 164 ? 109.597 32.948 -27.133 1.00 79.61 ? 164 VAL B CG1 1 ATOM 2838 C CG2 . VAL B 2 164 ? 111.345 31.309 -27.745 1.00 84.86 ? 164 VAL B CG2 1 ATOM 2839 N N . PRO B 2 165 ? 107.717 29.405 -29.578 1.00 96.52 ? 165 PRO B N 1 ATOM 2840 C CA . PRO B 2 165 ? 107.489 28.531 -30.728 1.00 101.32 ? 165 PRO B CA 1 ATOM 2841 C C . PRO B 2 165 ? 108.041 29.019 -32.063 1.00 106.15 ? 165 PRO B C 1 ATOM 2842 O O . PRO B 2 165 ? 107.626 30.066 -32.565 1.00 107.33 ? 165 PRO B O 1 ATOM 2843 C CB . PRO B 2 165 ? 105.964 28.409 -30.769 1.00 101.69 ? 165 PRO B CB 1 ATOM 2844 C CG . PRO B 2 165 ? 105.546 28.682 -29.353 1.00 99.96 ? 165 PRO B CG 1 ATOM 2845 C CD . PRO B 2 165 ? 106.434 29.829 -28.996 1.00 97.92 ? 165 PRO B CD 1 ATOM 2846 N N . ARG B 2 166 ? 108.968 28.252 -32.633 1.00 110.87 ? 166 ARG B N 1 ATOM 2847 C CA . ARG B 2 166 ? 109.549 28.567 -33.942 1.00 115.08 ? 166 ARG B CA 1 ATOM 2848 C C . ARG B 2 166 ? 109.030 27.531 -34.948 1.00 115.84 ? 166 ARG B C 1 ATOM 2849 O O . ARG B 2 166 ? 108.868 26.357 -34.603 1.00 117.45 ? 166 ARG B O 1 ATOM 2850 C CB . ARG B 2 166 ? 111.084 28.527 -33.893 1.00 116.95 ? 166 ARG B CB 1 ATOM 2851 C CG . ARG B 2 166 ? 111.744 29.833 -33.445 1.00 120.84 ? 166 ARG B CG 1 ATOM 2852 C CD . ARG B 2 166 ? 111.378 30.195 -32.010 1.00 126.49 ? 166 ARG B CD 1 ATOM 2853 N NE . ARG B 2 166 ? 111.986 31.451 -31.562 1.00 131.31 ? 166 ARG B NE 1 ATOM 2854 C CZ . ARG B 2 166 ? 111.652 32.663 -32.007 1.00 132.09 ? 166 ARG B CZ 1 ATOM 2855 N NH1 . ARG B 2 166 ? 110.703 32.804 -32.925 1.00 131.99 ? 166 ARG B NH1 1 ATOM 2856 N NH2 . ARG B 2 166 ? 112.266 33.740 -31.529 1.00 131.77 ? 166 ARG B NH2 1 ATOM 2857 N N . SER B 2 167 ? 108.760 27.965 -36.180 1.00 115.76 ? 167 SER B N 1 ATOM 2858 C CA . SER B 2 167 ? 108.246 27.059 -37.211 1.00 113.99 ? 167 SER B CA 1 ATOM 2859 C C . SER B 2 167 ? 109.360 26.179 -37.768 1.00 111.92 ? 167 SER B C 1 ATOM 2860 O O . SER B 2 167 ? 109.826 26.359 -38.894 1.00 111.82 ? 167 SER B O 1 ATOM 2861 C CB . SER B 2 167 ? 107.574 27.850 -38.344 1.00 114.12 ? 167 SER B CB 1 ATOM 2862 O OG . SER B 2 167 ? 106.760 27.006 -39.146 1.00 111.99 ? 167 SER B OG 1 ATOM 2863 N N . GLY B 2 168 ? 109.773 25.220 -36.950 1.00 109.83 ? 168 GLY B N 1 ATOM 2864 C CA . GLY B 2 168 ? 110.828 24.298 -37.317 1.00 105.84 ? 168 GLY B CA 1 ATOM 2865 C C . GLY B 2 168 ? 111.127 23.468 -36.088 1.00 102.35 ? 168 GLY B C 1 ATOM 2866 O O . GLY B 2 168 ? 111.206 22.240 -36.152 1.00 102.47 ? 168 GLY B O 1 ATOM 2867 N N . GLU B 2 169 ? 111.286 24.154 -34.959 1.00 97.98 ? 169 GLU B N 1 ATOM 2868 C CA . GLU B 2 169 ? 111.551 23.491 -33.694 1.00 91.99 ? 169 GLU B CA 1 ATOM 2869 C C . GLU B 2 169 ? 110.506 22.400 -33.503 1.00 89.71 ? 169 GLU B C 1 ATOM 2870 O O . GLU B 2 169 ? 109.313 22.639 -33.710 1.00 88.87 ? 169 GLU B O 1 ATOM 2871 C CB . GLU B 2 169 ? 111.437 24.481 -32.528 1.00 90.79 ? 169 GLU B CB 1 ATOM 2872 C CG . GLU B 2 169 ? 112.540 25.520 -32.423 1.00 90.51 ? 169 GLU B CG 1 ATOM 2873 C CD . GLU B 2 169 ? 112.372 26.421 -31.201 1.00 92.47 ? 169 GLU B CD 1 ATOM 2874 O OE1 . GLU B 2 169 ? 111.462 27.281 -31.199 1.00 92.32 ? 169 GLU B OE1 1 ATOM 2875 O OE2 . GLU B 2 169 ? 113.147 26.261 -30.233 1.00 92.07 ? 169 GLU B OE2 1 ATOM 2876 N N . VAL B 2 170 ? 110.958 21.205 -33.132 1.00 85.99 ? 170 VAL B N 1 ATOM 2877 C CA . VAL B 2 170 ? 110.057 20.089 -32.863 1.00 81.13 ? 170 VAL B CA 1 ATOM 2878 C C . VAL B 2 170 ? 110.248 19.656 -31.412 1.00 80.67 ? 170 VAL B C 1 ATOM 2879 O O . VAL B 2 170 ? 111.212 18.957 -31.082 1.00 79.93 ? 170 VAL B O 1 ATOM 2880 C CB . VAL B 2 170 ? 110.325 18.877 -33.774 1.00 76.52 ? 170 VAL B CB 1 ATOM 2881 C CG1 . VAL B 2 170 ? 109.833 19.163 -35.174 1.00 75.24 ? 170 VAL B CG1 1 ATOM 2882 C CG2 . VAL B 2 170 ? 111.798 18.550 -33.773 1.00 74.70 ? 170 VAL B CG2 1 ATOM 2883 N N . TYR B 2 171 ? 109.335 20.097 -30.546 1.00 78.23 ? 171 TYR B N 1 ATOM 2884 C CA . TYR B 2 171 ? 109.392 19.754 -29.129 1.00 74.05 ? 171 TYR B CA 1 ATOM 2885 C C . TYR B 2 171 ? 108.744 18.389 -28.922 1.00 72.31 ? 171 TYR B C 1 ATOM 2886 O O . TYR B 2 171 ? 107.665 18.125 -29.461 1.00 73.49 ? 171 TYR B O 1 ATOM 2887 C CB . TYR B 2 171 ? 108.646 20.792 -28.284 1.00 70.51 ? 171 TYR B CB 1 ATOM 2888 C CG . TYR B 2 171 ? 109.097 22.229 -28.454 1.00 65.59 ? 171 TYR B CG 1 ATOM 2889 C CD1 . TYR B 2 171 ? 108.669 22.996 -29.541 1.00 62.34 ? 171 TYR B CD1 1 ATOM 2890 C CD2 . TYR B 2 171 ? 109.897 22.841 -27.492 1.00 60.97 ? 171 TYR B CD2 1 ATOM 2891 C CE1 . TYR B 2 171 ? 109.020 24.340 -29.657 1.00 60.09 ? 171 TYR B CE1 1 ATOM 2892 C CE2 . TYR B 2 171 ? 110.253 24.182 -27.600 1.00 60.09 ? 171 TYR B CE2 1 ATOM 2893 C CZ . TYR B 2 171 ? 109.811 24.927 -28.679 1.00 59.81 ? 171 TYR B CZ 1 ATOM 2894 O OH . TYR B 2 171 ? 110.149 26.259 -28.764 1.00 58.53 ? 171 TYR B OH 1 ATOM 2895 N N . THR B 2 172 ? 109.402 17.526 -28.149 1.00 68.66 ? 172 THR B N 1 ATOM 2896 C CA . THR B 2 172 ? 108.877 16.190 -27.872 1.00 65.84 ? 172 THR B CA 1 ATOM 2897 C C . THR B 2 172 ? 108.742 15.928 -26.377 1.00 62.97 ? 172 THR B C 1 ATOM 2898 O O . THR B 2 172 ? 109.569 16.388 -25.585 1.00 59.61 ? 172 THR B O 1 ATOM 2899 C CB . THR B 2 172 ? 109.790 15.084 -28.462 1.00 67.38 ? 172 THR B CB 1 ATOM 2900 O OG1 . THR B 2 172 ? 111.139 15.563 -28.544 1.00 68.77 ? 172 THR B OG1 1 ATOM 2901 C CG2 . THR B 2 172 ? 109.311 14.661 -29.831 1.00 66.23 ? 172 THR B CG2 1 ATOM 2902 N N . CYS B 2 173 ? 107.689 15.208 -25.992 1.00 61.28 ? 173 CYS B N 1 ATOM 2903 C CA . CYS B 2 173 ? 107.495 14.857 -24.588 1.00 60.87 ? 173 CYS B CA 1 ATOM 2904 C C . CYS B 2 173 ? 107.816 13.383 -24.492 1.00 61.12 ? 173 CYS B C 1 ATOM 2905 O O . CYS B 2 173 ? 107.242 12.572 -25.218 1.00 59.04 ? 173 CYS B O 1 ATOM 2906 C CB . CYS B 2 173 ? 106.050 15.087 -24.113 1.00 60.07 ? 173 CYS B CB 1 ATOM 2907 S SG . CYS B 2 173 ? 105.799 14.674 -22.343 1.00 52.79 ? 173 CYS B SG 1 ATOM 2908 N N . GLN B 2 174 ? 108.747 13.045 -23.607 1.00 63.13 ? 174 GLN B N 1 ATOM 2909 C CA . GLN B 2 174 ? 109.147 11.660 -23.420 1.00 66.54 ? 174 GLN B CA 1 ATOM 2910 C C . GLN B 2 174 ? 108.718 11.182 -22.034 1.00 68.73 ? 174 GLN B C 1 ATOM 2911 O O . GLN B 2 174 ? 109.099 11.767 -21.011 1.00 66.76 ? 174 GLN B O 1 ATOM 2912 C CB . GLN B 2 174 ? 110.658 11.530 -23.578 1.00 68.22 ? 174 GLN B CB 1 ATOM 2913 C CG . GLN B 2 174 ? 111.140 10.101 -23.661 1.00 71.59 ? 174 GLN B CG 1 ATOM 2914 C CD . GLN B 2 174 ? 112.644 10.007 -23.606 1.00 73.81 ? 174 GLN B CD 1 ATOM 2915 O OE1 . GLN B 2 174 ? 113.266 10.465 -22.651 1.00 72.61 ? 174 GLN B OE1 1 ATOM 2916 N NE2 . GLN B 2 174 ? 113.241 9.412 -24.632 1.00 75.36 ? 174 GLN B NE2 1 ATOM 2917 N N . VAL B 2 175 ? 107.918 10.118 -22.017 1.00 69.99 ? 175 VAL B N 1 ATOM 2918 C CA . VAL B 2 175 ? 107.403 9.538 -20.784 1.00 71.42 ? 175 VAL B CA 1 ATOM 2919 C C . VAL B 2 175 ? 107.991 8.154 -20.549 1.00 71.61 ? 175 VAL B C 1 ATOM 2920 O O . VAL B 2 175 ? 107.844 7.265 -21.385 1.00 71.19 ? 175 VAL B O 1 ATOM 2921 C CB . VAL B 2 175 ? 105.859 9.404 -20.836 1.00 73.12 ? 175 VAL B CB 1 ATOM 2922 C CG1 . VAL B 2 175 ? 105.344 8.753 -19.557 1.00 74.27 ? 175 VAL B CG1 1 ATOM 2923 C CG2 . VAL B 2 175 ? 105.222 10.769 -21.024 1.00 73.33 ? 175 VAL B CG2 1 ATOM 2924 N N . GLU B 2 176 ? 108.658 7.977 -19.413 1.00 72.74 ? 176 GLU B N 1 ATOM 2925 C CA . GLU B 2 176 ? 109.250 6.691 -19.064 1.00 74.49 ? 176 GLU B CA 1 ATOM 2926 C C . GLU B 2 176 ? 108.539 6.164 -17.834 1.00 72.71 ? 176 GLU B C 1 ATOM 2927 O O . GLU B 2 176 ? 108.582 6.792 -16.773 1.00 74.31 ? 176 GLU B O 1 ATOM 2928 C CB . GLU B 2 176 ? 110.735 6.846 -18.763 1.00 79.64 ? 176 GLU B CB 1 ATOM 2929 C CG . GLU B 2 176 ? 111.521 7.506 -19.872 1.00 86.03 ? 176 GLU B CG 1 ATOM 2930 C CD . GLU B 2 176 ? 113.010 7.402 -19.652 1.00 89.56 ? 176 GLU B CD 1 ATOM 2931 O OE1 . GLU B 2 176 ? 113.584 6.333 -19.957 1.00 90.17 ? 176 GLU B OE1 1 ATOM 2932 O OE2 . GLU B 2 176 ? 113.600 8.387 -19.159 1.00 92.18 ? 176 GLU B OE2 1 ATOM 2933 N N . HIS B 2 177 ? 107.896 5.006 -17.978 1.00 70.08 ? 177 HIS B N 1 ATOM 2934 C CA . HIS B 2 177 ? 107.131 4.392 -16.887 1.00 65.07 ? 177 HIS B CA 1 ATOM 2935 C C . HIS B 2 177 ? 107.122 2.858 -16.963 1.00 61.95 ? 177 HIS B C 1 ATOM 2936 O O . HIS B 2 177 ? 106.883 2.280 -18.022 1.00 65.25 ? 177 HIS B O 1 ATOM 2937 C CB . HIS B 2 177 ? 105.704 4.952 -16.921 1.00 58.21 ? 177 HIS B CB 1 ATOM 2938 C CG . HIS B 2 177 ? 104.753 4.280 -15.986 1.00 49.42 ? 177 HIS B CG 1 ATOM 2939 N ND1 . HIS B 2 177 ? 104.112 3.102 -16.299 1.00 48.07 ? 177 HIS B ND1 1 ATOM 2940 C CD2 . HIS B 2 177 ? 104.281 4.656 -14.775 1.00 47.10 ? 177 HIS B CD2 1 ATOM 2941 C CE1 . HIS B 2 177 ? 103.278 2.785 -15.325 1.00 48.44 ? 177 HIS B CE1 1 ATOM 2942 N NE2 . HIS B 2 177 ? 103.361 3.712 -14.388 1.00 49.05 ? 177 HIS B NE2 1 ATOM 2943 N N . PRO B 2 178 ? 107.375 2.186 -15.830 1.00 56.02 ? 178 PRO B N 1 ATOM 2944 C CA . PRO B 2 178 ? 107.411 0.726 -15.731 1.00 54.01 ? 178 PRO B CA 1 ATOM 2945 C C . PRO B 2 178 ? 106.181 -0.047 -16.195 1.00 55.95 ? 178 PRO B C 1 ATOM 2946 O O . PRO B 2 178 ? 105.723 -0.943 -15.498 1.00 60.07 ? 178 PRO B O 1 ATOM 2947 C CB . PRO B 2 178 ? 107.699 0.497 -14.251 1.00 51.25 ? 178 PRO B CB 1 ATOM 2948 C CG . PRO B 2 178 ? 107.072 1.675 -13.602 1.00 49.83 ? 178 PRO B CG 1 ATOM 2949 C CD . PRO B 2 178 ? 107.520 2.791 -14.498 1.00 53.01 ? 178 PRO B CD 1 ATOM 2950 N N . SER B 2 179 ? 105.643 0.283 -17.362 1.00 56.89 ? 179 SER B N 1 ATOM 2951 C CA . SER B 2 179 ? 104.473 -0.425 -17.878 1.00 59.53 ? 179 SER B CA 1 ATOM 2952 C C . SER B 2 179 ? 104.594 -0.513 -19.389 1.00 62.53 ? 179 SER B C 1 ATOM 2953 O O . SER B 2 179 ? 103.696 -1.002 -20.079 1.00 63.88 ? 179 SER B O 1 ATOM 2954 C CB . SER B 2 179 ? 103.179 0.302 -17.502 1.00 58.90 ? 179 SER B CB 1 ATOM 2955 O OG . SER B 2 179 ? 103.062 1.546 -18.172 1.00 60.16 ? 179 SER B OG 1 ATOM 2956 N N . VAL B 2 180 ? 105.720 -0.019 -19.891 1.00 64.39 ? 180 VAL B N 1 ATOM 2957 C CA . VAL B 2 180 ? 106.006 -0.038 -21.313 1.00 64.52 ? 180 VAL B CA 1 ATOM 2958 C C . VAL B 2 180 ? 107.452 -0.429 -21.545 1.00 67.11 ? 180 VAL B C 1 ATOM 2959 O O . VAL B 2 180 ? 108.373 0.072 -20.892 1.00 61.30 ? 180 VAL B O 1 ATOM 2960 C CB . VAL B 2 180 ? 105.759 1.325 -21.970 1.00 63.28 ? 180 VAL B CB 1 ATOM 2961 C CG1 . VAL B 2 180 ? 104.285 1.640 -21.941 1.00 61.77 ? 180 VAL B CG1 1 ATOM 2962 C CG2 . VAL B 2 180 ? 106.570 2.401 -21.264 1.00 60.90 ? 180 VAL B CG2 1 ATOM 2963 N N . THR B 2 181 ? 107.619 -1.339 -22.497 1.00 72.42 ? 181 THR B N 1 ATOM 2964 C CA . THR B 2 181 ? 108.909 -1.871 -22.893 1.00 76.51 ? 181 THR B CA 1 ATOM 2965 C C . THR B 2 181 ? 109.839 -0.732 -23.363 1.00 79.25 ? 181 THR B C 1 ATOM 2966 O O . THR B 2 181 ? 110.993 -0.643 -22.924 1.00 78.61 ? 181 THR B O 1 ATOM 2967 C CB . THR B 2 181 ? 108.681 -2.955 -24.001 1.00 76.72 ? 181 THR B CB 1 ATOM 2968 O OG1 . THR B 2 181 ? 109.910 -3.628 -24.303 1.00 79.81 ? 181 THR B OG1 1 ATOM 2969 C CG2 . THR B 2 181 ? 108.083 -2.324 -25.256 1.00 74.13 ? 181 THR B CG2 1 ATOM 2970 N N . SER B 2 182 ? 109.322 0.145 -24.227 1.00 82.20 ? 182 SER B N 1 ATOM 2971 C CA . SER B 2 182 ? 110.080 1.291 -24.756 1.00 82.93 ? 182 SER B CA 1 ATOM 2972 C C . SER B 2 182 ? 109.431 2.634 -24.388 1.00 80.16 ? 182 SER B C 1 ATOM 2973 O O . SER B 2 182 ? 108.210 2.732 -24.261 1.00 79.61 ? 182 SER B O 1 ATOM 2974 C CB . SER B 2 182 ? 110.219 1.180 -26.285 1.00 86.48 ? 182 SER B CB 1 ATOM 2975 O OG . SER B 2 182 ? 108.974 0.908 -26.917 1.00 91.17 ? 182 SER B OG 1 ATOM 2976 N N . PRO B 2 183 ? 110.245 3.690 -24.216 1.00 77.61 ? 183 PRO B N 1 ATOM 2977 C CA . PRO B 2 183 ? 109.710 5.004 -23.858 1.00 75.64 ? 183 PRO B CA 1 ATOM 2978 C C . PRO B 2 183 ? 108.558 5.482 -24.729 1.00 73.52 ? 183 PRO B C 1 ATOM 2979 O O . PRO B 2 183 ? 108.468 5.144 -25.912 1.00 72.57 ? 183 PRO B O 1 ATOM 2980 C CB . PRO B 2 183 ? 110.934 5.909 -23.959 1.00 75.12 ? 183 PRO B CB 1 ATOM 2981 C CG . PRO B 2 183 ? 112.017 5.016 -23.500 1.00 77.95 ? 183 PRO B CG 1 ATOM 2982 C CD . PRO B 2 183 ? 111.714 3.737 -24.269 1.00 78.98 ? 183 PRO B CD 1 ATOM 2983 N N . LEU B 2 184 ? 107.674 6.261 -24.110 1.00 70.68 ? 184 LEU B N 1 ATOM 2984 C CA . LEU B 2 184 ? 106.513 6.831 -24.778 1.00 65.75 ? 184 LEU B CA 1 ATOM 2985 C C . LEU B 2 184 ? 106.857 8.258 -25.148 1.00 65.61 ? 184 LEU B C 1 ATOM 2986 O O . LEU B 2 184 ? 107.267 9.044 -24.293 1.00 64.16 ? 184 LEU B O 1 ATOM 2987 C CB . LEU B 2 184 ? 105.297 6.832 -23.847 1.00 58.82 ? 184 LEU B CB 1 ATOM 2988 C CG . LEU B 2 184 ? 104.533 5.522 -23.659 1.00 51.21 ? 184 LEU B CG 1 ATOM 2989 C CD1 . LEU B 2 184 ? 103.453 5.739 -22.629 1.00 50.22 ? 184 LEU B CD1 1 ATOM 2990 C CD2 . LEU B 2 184 ? 103.932 5.068 -24.973 1.00 46.11 ? 184 LEU B CD2 1 ATOM 2991 N N . THR B 2 185 ? 106.704 8.587 -26.426 1.00 66.10 ? 185 THR B N 1 ATOM 2992 C CA . THR B 2 185 ? 106.996 9.931 -26.893 1.00 67.33 ? 185 THR B CA 1 ATOM 2993 C C . THR B 2 185 ? 105.917 10.456 -27.813 1.00 68.84 ? 185 THR B C 1 ATOM 2994 O O . THR B 2 185 ? 105.328 9.714 -28.604 1.00 69.63 ? 185 THR B O 1 ATOM 2995 C CB . THR B 2 185 ? 108.331 10.011 -27.656 1.00 66.31 ? 185 THR B CB 1 ATOM 2996 O OG1 . THR B 2 185 ? 108.309 9.097 -28.760 1.00 64.89 ? 185 THR B OG1 1 ATOM 2997 C CG2 . THR B 2 185 ? 109.493 9.689 -26.733 1.00 67.70 ? 185 THR B CG2 1 ATOM 2998 N N . VAL B 2 186 ? 105.660 11.750 -27.679 1.00 70.27 ? 186 VAL B N 1 ATOM 2999 C CA . VAL B 2 186 ? 104.690 12.439 -28.499 1.00 72.04 ? 186 VAL B CA 1 ATOM 3000 C C . VAL B 2 186 ? 105.379 13.725 -28.902 1.00 74.19 ? 186 VAL B C 1 ATOM 3001 O O . VAL B 2 186 ? 106.088 14.339 -28.098 1.00 71.12 ? 186 VAL B O 1 ATOM 3002 C CB . VAL B 2 186 ? 103.402 12.727 -27.730 1.00 71.82 ? 186 VAL B CB 1 ATOM 3003 C CG1 . VAL B 2 186 ? 102.592 13.782 -28.453 1.00 74.47 ? 186 VAL B CG1 1 ATOM 3004 C CG2 . VAL B 2 186 ? 102.585 11.450 -27.624 1.00 70.63 ? 186 VAL B CG2 1 ATOM 3005 N N . GLU B 2 187 ? 105.180 14.115 -30.157 1.00 77.36 ? 187 GLU B N 1 ATOM 3006 C CA . GLU B 2 187 ? 105.818 15.301 -30.698 1.00 81.34 ? 187 GLU B CA 1 ATOM 3007 C C . GLU B 2 187 ? 104.829 16.399 -31.028 1.00 82.36 ? 187 GLU B C 1 ATOM 3008 O O . GLU B 2 187 ? 103.642 16.149 -31.250 1.00 80.23 ? 187 GLU B O 1 ATOM 3009 C CB . GLU B 2 187 ? 106.598 14.931 -31.963 1.00 85.87 ? 187 GLU B CB 1 ATOM 3010 C CG . GLU B 2 187 ? 107.143 13.505 -31.951 1.00 92.87 ? 187 GLU B CG 1 ATOM 3011 C CD . GLU B 2 187 ? 107.898 13.137 -33.218 1.00 96.59 ? 187 GLU B CD 1 ATOM 3012 O OE1 . GLU B 2 187 ? 107.340 13.328 -34.322 1.00 99.61 ? 187 GLU B OE1 1 ATOM 3013 O OE2 . GLU B 2 187 ? 109.046 12.647 -33.107 1.00 97.54 ? 187 GLU B OE2 1 ATOM 3014 N N . TRP B 2 188 ? 105.348 17.621 -31.066 1.00 85.37 ? 188 TRP B N 1 ATOM 3015 C CA . TRP B 2 188 ? 104.560 18.798 -31.380 1.00 89.96 ? 188 TRP B CA 1 ATOM 3016 C C . TRP B 2 188 ? 105.501 19.892 -31.874 1.00 93.85 ? 188 TRP B C 1 ATOM 3017 O O . TRP B 2 188 ? 106.468 20.237 -31.190 1.00 91.46 ? 188 TRP B O 1 ATOM 3018 C CB . TRP B 2 188 ? 103.817 19.293 -30.139 1.00 89.92 ? 188 TRP B CB 1 ATOM 3019 C CG . TRP B 2 188 ? 102.991 20.506 -30.411 1.00 89.94 ? 188 TRP B CG 1 ATOM 3020 C CD1 . TRP B 2 188 ? 101.690 20.542 -30.821 1.00 88.46 ? 188 TRP B CD1 1 ATOM 3021 C CD2 . TRP B 2 188 ? 103.443 21.863 -30.393 1.00 91.10 ? 188 TRP B CD2 1 ATOM 3022 N NE1 . TRP B 2 188 ? 101.305 21.836 -31.065 1.00 88.20 ? 188 TRP B NE1 1 ATOM 3023 C CE2 . TRP B 2 188 ? 102.363 22.668 -30.811 1.00 89.99 ? 188 TRP B CE2 1 ATOM 3024 C CE3 . TRP B 2 188 ? 104.662 22.477 -30.068 1.00 92.30 ? 188 TRP B CE3 1 ATOM 3025 C CZ2 . TRP B 2 188 ? 102.462 24.058 -30.915 1.00 91.15 ? 188 TRP B CZ2 1 ATOM 3026 C CZ3 . TRP B 2 188 ? 104.763 23.859 -30.171 1.00 92.59 ? 188 TRP B CZ3 1 ATOM 3027 C CH2 . TRP B 2 188 ? 103.667 24.634 -30.592 1.00 92.37 ? 188 TRP B CH2 1 ATOM 3028 N N . ARG B 2 189 ? 105.217 20.430 -33.062 1.00 99.68 ? 189 ARG B N 1 ATOM 3029 C CA . ARG B 2 189 ? 106.031 21.498 -33.644 1.00 104.78 ? 189 ARG B CA 1 ATOM 3030 C C . ARG B 2 189 ? 105.202 22.478 -34.472 1.00 106.60 ? 189 ARG B C 1 ATOM 3031 O O . ARG B 2 189 ? 104.137 22.124 -34.981 1.00 105.11 ? 189 ARG B O 1 ATOM 3032 C CB . ARG B 2 189 ? 107.136 20.921 -34.532 1.00 106.69 ? 189 ARG B CB 1 ATOM 3033 C CG . ARG B 2 189 ? 106.628 20.251 -35.782 1.00 109.56 ? 189 ARG B CG 1 ATOM 3034 C CD . ARG B 2 189 ? 106.403 18.765 -35.576 1.00 113.87 ? 189 ARG B CD 1 ATOM 3035 N NE . ARG B 2 189 ? 105.420 18.237 -36.520 1.00 120.44 ? 189 ARG B NE 1 ATOM 3036 C CZ . ARG B 2 189 ? 105.424 18.472 -37.831 1.00 123.42 ? 189 ARG B CZ 1 ATOM 3037 N NH1 . ARG B 2 189 ? 106.365 19.234 -38.377 1.00 125.07 ? 189 ARG B NH1 1 ATOM 3038 N NH2 . ARG B 2 189 ? 104.477 17.949 -38.603 1.00 123.16 ? 189 ARG B NH2 1 ATOM 3039 N N . ALA B 2 190 ? 105.718 23.702 -34.595 1.00 110.12 ? 190 ALA B N 1 ATOM 3040 C CA . ALA B 2 190 ? 105.099 24.798 -35.350 1.00 113.07 ? 190 ALA B CA 1 ATOM 3041 C C . ALA B 2 190 ? 103.601 24.652 -35.628 1.00 115.34 ? 190 ALA B C 1 ATOM 3042 O O . ALA B 2 190 ? 103.185 24.948 -36.774 1.00 115.83 ? 190 ALA B O 1 ATOM 3043 C CB . ALA B 2 190 ? 105.847 24.995 -36.667 1.00 111.86 ? 190 ALA B CB 1 ATOM 3044 O OXT . ALA B 2 190 ? 102.857 24.271 -34.696 1.00 118.18 ? 190 ALA B OXT 1 ATOM 3045 N N . GLY C 3 1 ? 96.747 -14.464 -4.419 1.00 73.65 ? 628 GLY C N 1 ATOM 3046 C CA . GLY C 3 1 ? 95.477 -14.238 -3.658 1.00 73.37 ? 628 GLY C CA 1 ATOM 3047 C C . GLY C 3 1 ? 95.450 -14.940 -2.310 1.00 71.82 ? 628 GLY C C 1 ATOM 3048 O O . GLY C 3 1 ? 96.494 -15.350 -1.801 1.00 75.35 ? 628 GLY C O 1 ATOM 3049 N N . GLY C 3 2 ? 94.264 -15.078 -1.722 1.00 66.54 ? 629 GLY C N 1 ATOM 3050 C CA . GLY C 3 2 ? 94.168 -15.746 -0.438 1.00 59.98 ? 629 GLY C CA 1 ATOM 3051 C C . GLY C 3 2 ? 93.267 -15.050 0.564 1.00 56.39 ? 629 GLY C C 1 ATOM 3052 O O . GLY C 3 2 ? 92.137 -14.676 0.249 1.00 57.78 ? 629 GLY C O 1 ATOM 3053 N N . VAL C 3 3 ? 93.759 -14.887 1.787 1.00 50.05 ? 630 VAL C N 1 ATOM 3054 C CA . VAL C 3 3 ? 92.977 -14.232 2.817 1.00 44.92 ? 630 VAL C CA 1 ATOM 3055 C C . VAL C 3 3 ? 93.801 -13.282 3.667 1.00 43.63 ? 630 VAL C C 1 ATOM 3056 O O . VAL C 3 3 ? 94.917 -13.588 4.084 1.00 42.30 ? 630 VAL C O 1 ATOM 3057 C CB . VAL C 3 3 ? 92.281 -15.254 3.720 1.00 44.25 ? 630 VAL C CB 1 ATOM 3058 C CG1 . VAL C 3 3 ? 91.683 -14.564 4.938 1.00 46.24 ? 630 VAL C CG1 1 ATOM 3059 C CG2 . VAL C 3 3 ? 91.180 -15.930 2.945 1.00 46.05 ? 630 VAL C CG2 1 ATOM 3060 N N . TYR C 3 4 ? 93.215 -12.120 3.920 1.00 41.79 ? 631 TYR C N 1 ATOM 3061 C CA . TYR C 3 4 ? 93.846 -11.075 4.692 1.00 38.24 ? 631 TYR C CA 1 ATOM 3062 C C . TYR C 3 4 ? 93.791 -11.264 6.191 1.00 38.68 ? 631 TYR C C 1 ATOM 3063 O O . TYR C 3 4 ? 92.798 -11.735 6.731 1.00 37.56 ? 631 TYR C O 1 ATOM 3064 C CB . TYR C 3 4 ? 93.207 -9.748 4.317 1.00 34.32 ? 631 TYR C CB 1 ATOM 3065 C CG . TYR C 3 4 ? 93.791 -9.159 3.061 1.00 32.58 ? 631 TYR C CG 1 ATOM 3066 C CD1 . TYR C 3 4 ? 95.133 -8.789 3.013 1.00 31.37 ? 631 TYR C CD1 1 ATOM 3067 C CD2 . TYR C 3 4 ? 93.012 -8.961 1.924 1.00 30.73 ? 631 TYR C CD2 1 ATOM 3068 C CE1 . TYR C 3 4 ? 95.682 -8.237 1.879 1.00 26.29 ? 631 TYR C CE1 1 ATOM 3069 C CE2 . TYR C 3 4 ? 93.560 -8.406 0.778 1.00 26.77 ? 631 TYR C CE2 1 ATOM 3070 C CZ . TYR C 3 4 ? 94.896 -8.049 0.778 1.00 26.29 ? 631 TYR C CZ 1 ATOM 3071 O OH . TYR C 3 4 ? 95.470 -7.493 -0.319 1.00 33.37 ? 631 TYR C OH 1 ATOM 3072 N N . HIS C 3 5 ? 94.878 -10.894 6.857 1.00 40.46 ? 632 HIS C N 1 ATOM 3073 C CA . HIS C 3 5 ? 94.957 -10.983 8.308 1.00 44.92 ? 632 HIS C CA 1 ATOM 3074 C C . HIS C 3 5 ? 94.910 -9.568 8.870 1.00 44.77 ? 632 HIS C C 1 ATOM 3075 O O . HIS C 3 5 ? 95.518 -8.654 8.313 1.00 45.99 ? 632 HIS C O 1 ATOM 3076 C CB . HIS C 3 5 ? 96.272 -11.627 8.755 1.00 49.44 ? 632 HIS C CB 1 ATOM 3077 C CG . HIS C 3 5 ? 96.398 -13.075 8.411 1.00 53.43 ? 632 HIS C CG 1 ATOM 3078 N ND1 . HIS C 3 5 ? 97.490 -13.829 8.783 1.00 54.05 ? 632 HIS C ND1 1 ATOM 3079 C CD2 . HIS C 3 5 ? 95.581 -13.906 7.723 1.00 56.32 ? 632 HIS C CD2 1 ATOM 3080 C CE1 . HIS C 3 5 ? 97.340 -15.063 8.337 1.00 57.39 ? 632 HIS C CE1 1 ATOM 3081 N NE2 . HIS C 3 5 ? 96.191 -15.137 7.690 1.00 58.37 ? 632 HIS C NE2 1 ATOM 3082 N N . PHE C 3 6 ? 94.194 -9.385 9.972 1.00 42.61 ? 633 PHE C N 1 ATOM 3083 C CA . PHE C 3 6 ? 94.112 -8.078 10.598 1.00 39.79 ? 633 PHE C CA 1 ATOM 3084 C C . PHE C 3 6 ? 94.515 -8.248 12.040 1.00 40.34 ? 633 PHE C C 1 ATOM 3085 O O . PHE C 3 6 ? 94.075 -9.200 12.679 1.00 46.42 ? 633 PHE C O 1 ATOM 3086 C CB . PHE C 3 6 ? 92.685 -7.541 10.550 1.00 40.81 ? 633 PHE C CB 1 ATOM 3087 C CG . PHE C 3 6 ? 91.725 -8.284 11.433 1.00 39.44 ? 633 PHE C CG 1 ATOM 3088 C CD1 . PHE C 3 6 ? 91.107 -9.442 10.993 1.00 41.53 ? 633 PHE C CD1 1 ATOM 3089 C CD2 . PHE C 3 6 ? 91.453 -7.831 12.718 1.00 37.61 ? 633 PHE C CD2 1 ATOM 3090 C CE1 . PHE C 3 6 ? 90.232 -10.135 11.825 1.00 41.55 ? 633 PHE C CE1 1 ATOM 3091 C CE2 . PHE C 3 6 ? 90.583 -8.520 13.554 1.00 35.39 ? 633 PHE C CE2 1 ATOM 3092 C CZ . PHE C 3 6 ? 89.973 -9.670 13.108 1.00 36.34 ? 633 PHE C CZ 1 ATOM 3093 N N . VAL C 3 7 ? 95.351 -7.350 12.556 1.00 38.15 ? 634 VAL C N 1 ATOM 3094 C CA . VAL C 3 7 ? 95.765 -7.419 13.957 1.00 37.63 ? 634 VAL C CA 1 ATOM 3095 C C . VAL C 3 7 ? 94.546 -7.043 14.805 1.00 40.43 ? 634 VAL C C 1 ATOM 3096 O O . VAL C 3 7 ? 93.741 -6.211 14.395 1.00 43.93 ? 634 VAL C O 1 ATOM 3097 C CB . VAL C 3 7 ? 96.869 -6.425 14.259 1.00 32.94 ? 634 VAL C CB 1 ATOM 3098 C CG1 . VAL C 3 7 ? 97.529 -6.788 15.547 1.00 35.51 ? 634 VAL C CG1 1 ATOM 3099 C CG2 . VAL C 3 7 ? 97.861 -6.401 13.136 1.00 35.10 ? 634 VAL C CG2 1 ATOM 3100 N N . LYS C 3 8 ? 94.393 -7.640 15.980 1.00 40.32 ? 635 LYS C N 1 ATOM 3101 C CA . LYS C 3 8 ? 93.235 -7.325 16.794 1.00 39.11 ? 635 LYS C CA 1 ATOM 3102 C C . LYS C 3 8 ? 93.532 -6.295 17.853 1.00 40.51 ? 635 LYS C C 1 ATOM 3103 O O . LYS C 3 8 ? 94.645 -6.211 18.376 1.00 40.57 ? 635 LYS C O 1 ATOM 3104 C CB . LYS C 3 8 ? 92.686 -8.588 17.426 1.00 43.68 ? 635 LYS C CB 1 ATOM 3105 C CG . LYS C 3 8 ? 92.165 -9.577 16.406 1.00 54.22 ? 635 LYS C CG 1 ATOM 3106 C CD . LYS C 3 8 ? 91.651 -10.842 17.082 1.00 66.31 ? 635 LYS C CD 1 ATOM 3107 C CE . LYS C 3 8 ? 91.248 -11.904 16.067 1.00 69.60 ? 635 LYS C CE 1 ATOM 3108 N NZ . LYS C 3 8 ? 90.864 -13.170 16.751 1.00 70.67 ? 635 LYS C NZ 1 ATOM 3109 N N . LYS C 3 9 ? 92.517 -5.500 18.159 1.00 42.09 ? 636 LYS C N 1 ATOM 3110 C CA . LYS C 3 9 ? 92.638 -4.436 19.146 1.00 47.32 ? 636 LYS C CA 1 ATOM 3111 C C . LYS C 3 9 ? 92.347 -4.961 20.550 1.00 50.08 ? 636 LYS C C 1 ATOM 3112 O O . LYS C 3 9 ? 91.326 -5.608 20.783 1.00 52.38 ? 636 LYS C O 1 ATOM 3113 C CB . LYS C 3 9 ? 91.673 -3.290 18.786 1.00 46.22 ? 636 LYS C CB 1 ATOM 3114 C CG . LYS C 3 9 ? 91.659 -2.101 19.748 1.00 42.01 ? 636 LYS C CG 1 ATOM 3115 C CD . LYS C 3 9 ? 93.026 -1.432 19.851 1.00 39.46 ? 636 LYS C CD 1 ATOM 3116 C CE . LYS C 3 9 ? 92.993 -0.196 20.751 1.00 33.84 ? 636 LYS C CE 1 ATOM 3117 N NZ . LYS C 3 9 ? 94.349 0.401 20.935 1.00 27.61 ? 636 LYS C NZ 1 ATOM 3118 N N . HIS C 3 10 ? 93.257 -4.692 21.480 1.00 50.84 ? 637 HIS C N 1 ATOM 3119 C CA . HIS C 3 10 ? 93.094 -5.119 22.863 1.00 50.72 ? 637 HIS C CA 1 ATOM 3120 C C . HIS C 3 10 ? 93.151 -3.893 23.759 1.00 52.33 ? 637 HIS C C 1 ATOM 3121 O O . HIS C 3 10 ? 94.050 -3.069 23.629 1.00 53.72 ? 637 HIS C O 1 ATOM 3122 C CB . HIS C 3 10 ? 94.202 -6.090 23.228 1.00 49.77 ? 637 HIS C CB 1 ATOM 3123 C CG . HIS C 3 10 ? 94.163 -7.354 22.439 1.00 48.13 ? 637 HIS C CG 1 ATOM 3124 N ND1 . HIS C 3 10 ? 93.163 -8.290 22.587 1.00 48.64 ? 637 HIS C ND1 1 ATOM 3125 C CD2 . HIS C 3 10 ? 94.985 -7.825 21.474 1.00 48.41 ? 637 HIS C CD2 1 ATOM 3126 C CE1 . HIS C 3 10 ? 93.370 -9.284 21.744 1.00 51.73 ? 637 HIS C CE1 1 ATOM 3127 N NE2 . HIS C 3 10 ? 94.470 -9.026 21.057 1.00 51.28 ? 637 HIS C NE2 1 ATOM 3128 N N . VAL C 3 11 ? 92.200 -3.774 24.675 1.00 53.55 ? 638 VAL C N 1 ATOM 3129 C CA . VAL C 3 11 ? 92.157 -2.612 25.549 1.00 55.91 ? 638 VAL C CA 1 ATOM 3130 C C . VAL C 3 11 ? 92.493 -2.917 27.001 1.00 59.42 ? 638 VAL C C 1 ATOM 3131 O O . VAL C 3 11 ? 92.267 -4.025 27.479 1.00 59.63 ? 638 VAL C O 1 ATOM 3132 C CB . VAL C 3 11 ? 90.773 -1.967 25.502 1.00 54.65 ? 638 VAL C CB 1 ATOM 3133 C CG1 . VAL C 3 11 ? 89.766 -2.840 26.229 1.00 48.46 ? 638 VAL C CG1 1 ATOM 3134 C CG2 . VAL C 3 11 ? 90.838 -0.579 26.088 1.00 58.47 ? 638 VAL C CG2 1 ATOM 3135 N N . HIS C 3 12 ? 93.029 -1.923 27.701 1.00 63.14 ? 639 HIS C N 1 ATOM 3136 C CA . HIS C 3 12 ? 93.385 -2.090 29.106 1.00 66.94 ? 639 HIS C CA 1 ATOM 3137 C C . HIS C 3 12 ? 93.040 -0.886 29.961 1.00 68.55 ? 639 HIS C C 1 ATOM 3138 O O . HIS C 3 12 ? 93.729 0.141 29.918 1.00 68.46 ? 639 HIS C O 1 ATOM 3139 C CB . HIS C 3 12 ? 94.874 -2.361 29.257 1.00 72.28 ? 639 HIS C CB 1 ATOM 3140 C CG . HIS C 3 12 ? 95.332 -2.404 30.683 1.00 76.16 ? 639 HIS C CG 1 ATOM 3141 N ND1 . HIS C 3 12 ? 94.857 -3.328 31.591 1.00 75.46 ? 639 HIS C ND1 1 ATOM 3142 C CD2 . HIS C 3 12 ? 96.220 -1.634 31.357 1.00 77.17 ? 639 HIS C CD2 1 ATOM 3143 C CE1 . HIS C 3 12 ? 95.433 -3.126 32.762 1.00 75.86 ? 639 HIS C CE1 1 ATOM 3144 N NE2 . HIS C 3 12 ? 96.264 -2.104 32.648 1.00 77.73 ? 639 HIS C NE2 1 ATOM 3145 N N . GLU C 3 13 ? 91.985 -1.026 30.756 1.00 69.94 ? 640 GLU C N 1 ATOM 3146 C CA . GLU C 3 13 ? 91.558 0.050 31.638 1.00 73.21 ? 640 GLU C CA 1 ATOM 3147 C C . GLU C 3 13 ? 92.372 0.017 32.920 1.00 75.38 ? 640 GLU C C 1 ATOM 3148 O O . GLU C 3 13 ? 92.521 -1.035 33.541 1.00 74.81 ? 640 GLU C O 1 ATOM 3149 C CB . GLU C 3 13 ? 90.072 -0.083 31.981 1.00 70.19 ? 640 GLU C CB 1 ATOM 3150 C CG . GLU C 3 13 ? 89.589 0.948 32.987 1.00 65.52 ? 640 GLU C CG 1 ATOM 3151 C CD . GLU C 3 13 ? 88.108 0.840 33.262 1.00 62.79 ? 640 GLU C CD 1 ATOM 3152 O OE1 . GLU C 3 13 ? 87.614 -0.300 33.357 1.00 60.99 ? 640 GLU C OE1 1 ATOM 3153 O OE2 . GLU C 3 13 ? 87.444 1.890 33.396 1.00 59.85 ? 640 GLU C OE2 1 ATOM 3154 N N . SER C 3 14 ? 92.904 1.172 33.307 1.00 78.67 ? 641 SER C N 1 ATOM 3155 C CA . SER C 3 14 ? 93.696 1.281 34.521 1.00 80.33 ? 641 SER C CA 1 ATOM 3156 C C . SER C 3 14 ? 93.129 2.379 35.413 1.00 83.34 ? 641 SER C C 1 ATOM 3157 O O . SER C 3 14 ? 92.137 3.031 35.009 1.00 84.56 ? 641 SER C O 1 ATOM 3158 C CB . SER C 3 14 ? 95.154 1.590 34.179 1.00 78.08 ? 641 SER C CB 1 ATOM 3159 O OG . SER C 3 14 ? 95.245 2.739 33.358 1.00 79.93 ? 641 SER C OG 1 ATOM 3160 O OXT . SER C 3 14 ? 93.688 2.567 36.510 1.00 86.66 ? 641 SER C OXT 1 ATOM 3161 N N . GLU D 1 3 ? 90.017 32.592 20.133 1.00 98.90 ? 3 GLU D N 1 ATOM 3162 C CA . GLU D 1 3 ? 89.762 33.687 21.113 1.00 98.00 ? 3 GLU D CA 1 ATOM 3163 C C . GLU D 1 3 ? 89.359 34.989 20.428 1.00 98.01 ? 3 GLU D C 1 ATOM 3164 O O . GLU D 1 3 ? 88.423 35.013 19.620 1.00 99.33 ? 3 GLU D O 1 ATOM 3165 C CB . GLU D 1 3 ? 91.004 33.929 21.976 1.00 97.51 ? 3 GLU D CB 1 ATOM 3166 C CG . GLU D 1 3 ? 92.305 34.080 21.203 1.00 94.64 ? 3 GLU D CG 1 ATOM 3167 C CD . GLU D 1 3 ? 92.956 32.747 20.894 1.00 92.98 ? 3 GLU D CD 1 ATOM 3168 O OE1 . GLU D 1 3 ? 93.301 32.017 21.851 1.00 88.10 ? 3 GLU D OE1 1 ATOM 3169 O OE2 . GLU D 1 3 ? 93.124 32.432 19.695 1.00 93.83 ? 3 GLU D OE2 1 ATOM 3170 N N . GLU D 1 4 ? 90.068 36.069 20.751 1.00 95.32 ? 4 GLU D N 1 ATOM 3171 C CA . GLU D 1 4 ? 89.769 37.371 20.172 1.00 93.21 ? 4 GLU D CA 1 ATOM 3172 C C . GLU D 1 4 ? 91.011 38.089 19.625 1.00 89.75 ? 4 GLU D C 1 ATOM 3173 O O . GLU D 1 4 ? 90.940 38.766 18.604 1.00 90.07 ? 4 GLU D O 1 ATOM 3174 C CB . GLU D 1 4 ? 89.056 38.245 21.213 1.00 96.46 ? 4 GLU D CB 1 ATOM 3175 C CG . GLU D 1 4 ? 87.814 37.590 21.845 1.00 100.59 ? 4 GLU D CG 1 ATOM 3176 C CD . GLU D 1 4 ? 86.710 37.268 20.835 1.00 103.87 ? 4 GLU D CD 1 ATOM 3177 O OE1 . GLU D 1 4 ? 86.182 38.209 20.205 1.00 105.81 ? 4 GLU D OE1 1 ATOM 3178 O OE2 . GLU D 1 4 ? 86.366 36.074 20.672 1.00 103.80 ? 4 GLU D OE2 1 ATOM 3179 N N . HIS D 1 5 ? 92.146 37.939 20.294 1.00 85.41 ? 5 HIS D N 1 ATOM 3180 C CA . HIS D 1 5 ? 93.377 38.580 19.844 1.00 81.95 ? 5 HIS D CA 1 ATOM 3181 C C . HIS D 1 5 ? 94.559 37.890 20.485 1.00 81.36 ? 5 HIS D C 1 ATOM 3182 O O . HIS D 1 5 ? 94.537 37.599 21.680 1.00 82.76 ? 5 HIS D O 1 ATOM 3183 C CB . HIS D 1 5 ? 93.377 40.052 20.230 1.00 81.62 ? 5 HIS D CB 1 ATOM 3184 C CG . HIS D 1 5 ? 92.887 40.960 19.149 1.00 84.46 ? 5 HIS D CG 1 ATOM 3185 N ND1 . HIS D 1 5 ? 92.138 42.090 19.406 1.00 87.53 ? 5 HIS D ND1 1 ATOM 3186 C CD2 . HIS D 1 5 ? 93.071 40.929 17.809 1.00 85.32 ? 5 HIS D CD2 1 ATOM 3187 C CE1 . HIS D 1 5 ? 91.883 42.715 18.270 1.00 87.68 ? 5 HIS D CE1 1 ATOM 3188 N NE2 . HIS D 1 5 ? 92.438 42.032 17.286 1.00 87.68 ? 5 HIS D NE2 1 ATOM 3189 N N . VAL D 1 6 ? 95.598 37.629 19.702 1.00 78.64 ? 6 VAL D N 1 ATOM 3190 C CA . VAL D 1 6 ? 96.760 36.945 20.241 1.00 75.26 ? 6 VAL D CA 1 ATOM 3191 C C . VAL D 1 6 ? 98.088 37.531 19.804 1.00 76.49 ? 6 VAL D C 1 ATOM 3192 O O . VAL D 1 6 ? 98.300 37.828 18.624 1.00 77.73 ? 6 VAL D O 1 ATOM 3193 C CB . VAL D 1 6 ? 96.754 35.471 19.847 1.00 70.64 ? 6 VAL D CB 1 ATOM 3194 C CG1 . VAL D 1 6 ? 97.824 34.735 20.608 1.00 71.61 ? 6 VAL D CG1 1 ATOM 3195 C CG2 . VAL D 1 6 ? 95.410 34.873 20.129 1.00 71.35 ? 6 VAL D CG2 1 ATOM 3196 N N . ILE D 1 7 ? 98.985 37.689 20.773 1.00 75.36 ? 7 ILE D N 1 ATOM 3197 C CA . ILE D 1 7 ? 100.321 38.208 20.511 1.00 72.90 ? 7 ILE D CA 1 ATOM 3198 C C . ILE D 1 7 ? 101.266 37.062 20.829 1.00 70.16 ? 7 ILE D C 1 ATOM 3199 O O . ILE D 1 7 ? 101.183 36.458 21.900 1.00 66.07 ? 7 ILE D O 1 ATOM 3200 C CB . ILE D 1 7 ? 100.681 39.389 21.436 1.00 74.07 ? 7 ILE D CB 1 ATOM 3201 C CG1 . ILE D 1 7 ? 99.482 40.320 21.610 1.00 70.02 ? 7 ILE D CG1 1 ATOM 3202 C CG2 . ILE D 1 7 ? 101.844 40.167 20.835 1.00 74.09 ? 7 ILE D CG2 1 ATOM 3203 C CD1 . ILE D 1 7 ? 99.708 41.396 22.636 1.00 62.74 ? 7 ILE D CD1 1 ATOM 3204 N N . ILE D 1 8 ? 102.160 36.749 19.904 1.00 68.99 ? 8 ILE D N 1 ATOM 3205 C CA . ILE D 1 8 ? 103.078 35.658 20.156 1.00 70.92 ? 8 ILE D CA 1 ATOM 3206 C C . ILE D 1 8 ? 104.530 36.063 19.984 1.00 70.26 ? 8 ILE D C 1 ATOM 3207 O O . ILE D 1 8 ? 104.902 36.708 18.994 1.00 66.83 ? 8 ILE D O 1 ATOM 3208 C CB . ILE D 1 8 ? 102.801 34.454 19.222 1.00 74.49 ? 8 ILE D CB 1 ATOM 3209 C CG1 . ILE D 1 8 ? 101.320 34.073 19.273 1.00 77.68 ? 8 ILE D CG1 1 ATOM 3210 C CG2 . ILE D 1 8 ? 103.628 33.251 19.663 1.00 75.37 ? 8 ILE D CG2 1 ATOM 3211 C CD1 . ILE D 1 8 ? 100.955 32.895 18.380 1.00 77.95 ? 8 ILE D CD1 1 ATOM 3212 N N . GLN D 1 9 ? 105.336 35.710 20.983 1.00 69.43 ? 9 GLN D N 1 ATOM 3213 C CA . GLN D 1 9 ? 106.765 35.955 20.930 1.00 68.30 ? 9 GLN D CA 1 ATOM 3214 C C . GLN D 1 9 ? 107.198 34.602 20.404 1.00 68.51 ? 9 GLN D C 1 ATOM 3215 O O . GLN D 1 9 ? 107.106 33.591 21.112 1.00 66.30 ? 9 GLN D O 1 ATOM 3216 C CB . GLN D 1 9 ? 107.358 36.168 22.321 1.00 68.67 ? 9 GLN D CB 1 ATOM 3217 C CG . GLN D 1 9 ? 108.829 36.596 22.288 1.00 68.25 ? 9 GLN D CG 1 ATOM 3218 C CD . GLN D 1 9 ? 109.533 36.395 23.615 1.00 67.53 ? 9 GLN D CD 1 ATOM 3219 O OE1 . GLN D 1 9 ? 108.970 36.673 24.672 1.00 68.40 ? 9 GLN D OE1 1 ATOM 3220 N NE2 . GLN D 1 9 ? 110.776 35.917 23.565 1.00 64.71 ? 9 GLN D NE2 1 ATOM 3221 N N . ALA D 1 10 ? 107.638 34.572 19.155 1.00 67.35 ? 10 ALA D N 1 ATOM 3222 C CA . ALA D 1 10 ? 108.035 33.318 18.549 1.00 67.89 ? 10 ALA D CA 1 ATOM 3223 C C . ALA D 1 10 ? 109.509 33.304 18.186 1.00 69.09 ? 10 ALA D C 1 ATOM 3224 O O . ALA D 1 10 ? 110.000 34.250 17.569 1.00 69.58 ? 10 ALA D O 1 ATOM 3225 C CB . ALA D 1 10 ? 107.191 33.074 17.310 1.00 67.94 ? 10 ALA D CB 1 ATOM 3226 N N . GLU D 1 11 ? 110.207 32.232 18.568 1.00 69.41 ? 11 GLU D N 1 ATOM 3227 C CA . GLU D 1 11 ? 111.635 32.082 18.263 1.00 68.40 ? 11 GLU D CA 1 ATOM 3228 C C . GLU D 1 11 ? 112.014 30.628 17.959 1.00 66.92 ? 11 GLU D C 1 ATOM 3229 O O . GLU D 1 11 ? 111.318 29.698 18.375 1.00 65.18 ? 11 GLU D O 1 ATOM 3230 C CB . GLU D 1 11 ? 112.496 32.634 19.417 1.00 66.72 ? 11 GLU D CB 1 ATOM 3231 C CG . GLU D 1 11 ? 112.353 31.918 20.750 1.00 63.08 ? 11 GLU D CG 1 ATOM 3232 C CD . GLU D 1 11 ? 112.903 32.738 21.908 1.00 62.45 ? 11 GLU D CD 1 ATOM 3233 O OE1 . GLU D 1 11 ? 113.030 32.194 23.029 1.00 62.54 ? 11 GLU D OE1 1 ATOM 3234 O OE2 . GLU D 1 11 ? 113.199 33.933 21.696 1.00 61.05 ? 11 GLU D OE2 1 ATOM 3235 N N . PHE D 1 12 ? 113.110 30.437 17.226 1.00 65.76 ? 12 PHE D N 1 ATOM 3236 C CA . PHE D 1 12 ? 113.556 29.096 16.872 1.00 63.79 ? 12 PHE D CA 1 ATOM 3237 C C . PHE D 1 12 ? 115.024 29.029 16.489 1.00 66.88 ? 12 PHE D C 1 ATOM 3238 O O . PHE D 1 12 ? 115.568 29.974 15.921 1.00 68.72 ? 12 PHE D O 1 ATOM 3239 C CB . PHE D 1 12 ? 112.718 28.563 15.709 1.00 57.89 ? 12 PHE D CB 1 ATOM 3240 C CG . PHE D 1 12 ? 113.103 29.125 14.357 1.00 52.98 ? 12 PHE D CG 1 ATOM 3241 C CD1 . PHE D 1 12 ? 114.266 28.711 13.718 1.00 50.47 ? 12 PHE D CD1 1 ATOM 3242 C CD2 . PHE D 1 12 ? 112.268 30.022 13.698 1.00 52.39 ? 12 PHE D CD2 1 ATOM 3243 C CE1 . PHE D 1 12 ? 114.589 29.172 12.446 1.00 50.91 ? 12 PHE D CE1 1 ATOM 3244 C CE2 . PHE D 1 12 ? 112.582 30.489 12.423 1.00 50.54 ? 12 PHE D CE2 1 ATOM 3245 C CZ . PHE D 1 12 ? 113.747 30.060 11.797 1.00 51.97 ? 12 PHE D CZ 1 ATOM 3246 N N . TYR D 1 13 ? 115.659 27.902 16.798 1.00 70.55 ? 13 TYR D N 1 ATOM 3247 C CA . TYR D 1 13 ? 117.057 27.689 16.440 1.00 73.31 ? 13 TYR D CA 1 ATOM 3248 C C . TYR D 1 13 ? 117.166 26.394 15.633 1.00 73.15 ? 13 TYR D C 1 ATOM 3249 O O . TYR D 1 13 ? 116.588 25.370 16.004 1.00 73.36 ? 13 TYR D O 1 ATOM 3250 C CB . TYR D 1 13 ? 117.941 27.603 17.686 1.00 77.05 ? 13 TYR D CB 1 ATOM 3251 C CG . TYR D 1 13 ? 119.400 27.776 17.347 1.00 82.30 ? 13 TYR D CG 1 ATOM 3252 C CD1 . TYR D 1 13 ? 120.201 26.680 17.013 1.00 82.22 ? 13 TYR D CD1 1 ATOM 3253 C CD2 . TYR D 1 13 ? 119.961 29.052 17.266 1.00 85.90 ? 13 TYR D CD2 1 ATOM 3254 C CE1 . TYR D 1 13 ? 121.525 26.854 16.600 1.00 82.96 ? 13 TYR D CE1 1 ATOM 3255 C CE2 . TYR D 1 13 ? 121.280 29.238 16.854 1.00 86.86 ? 13 TYR D CE2 1 ATOM 3256 C CZ . TYR D 1 13 ? 122.054 28.135 16.521 1.00 84.97 ? 13 TYR D CZ 1 ATOM 3257 O OH . TYR D 1 13 ? 123.349 28.320 16.105 1.00 84.52 ? 13 TYR D OH 1 ATOM 3258 N N . LEU D 1 14 ? 117.896 26.443 14.525 1.00 72.68 ? 14 LEU D N 1 ATOM 3259 C CA . LEU D 1 14 ? 118.055 25.272 13.666 1.00 75.86 ? 14 LEU D CA 1 ATOM 3260 C C . LEU D 1 14 ? 119.506 24.816 13.707 1.00 80.52 ? 14 LEU D C 1 ATOM 3261 O O . LEU D 1 14 ? 120.362 25.401 13.050 1.00 82.62 ? 14 LEU D O 1 ATOM 3262 C CB . LEU D 1 14 ? 117.658 25.631 12.237 1.00 71.19 ? 14 LEU D CB 1 ATOM 3263 C CG . LEU D 1 14 ? 117.746 24.515 11.203 1.00 69.42 ? 14 LEU D CG 1 ATOM 3264 C CD1 . LEU D 1 14 ? 116.690 23.464 11.492 1.00 69.70 ? 14 LEU D CD1 1 ATOM 3265 C CD2 . LEU D 1 14 ? 117.545 25.096 9.822 1.00 65.60 ? 14 LEU D CD2 1 ATOM 3266 N N . ASN D 1 15 ? 119.770 23.756 14.467 1.00 85.21 ? 15 ASN D N 1 ATOM 3267 C CA . ASN D 1 15 ? 121.127 23.248 14.665 1.00 89.76 ? 15 ASN D CA 1 ATOM 3268 C C . ASN D 1 15 ? 122.057 23.011 13.471 1.00 91.38 ? 15 ASN D C 1 ATOM 3269 O O . ASN D 1 15 ? 123.107 23.647 13.371 1.00 93.79 ? 15 ASN D O 1 ATOM 3270 C CB . ASN D 1 15 ? 121.086 21.985 15.526 1.00 92.67 ? 15 ASN D CB 1 ATOM 3271 C CG . ASN D 1 15 ? 122.114 22.016 16.646 1.00 98.23 ? 15 ASN D CG 1 ATOM 3272 O OD1 . ASN D 1 15 ? 123.318 22.124 16.398 1.00 99.94 ? 15 ASN D OD1 1 ATOM 3273 N ND2 . ASN D 1 15 ? 121.643 21.930 17.887 1.00 100.79 ? 15 ASN D ND2 1 ATOM 3274 N N . PRO D 1 16 ? 121.700 22.098 12.554 1.00 91.37 ? 16 PRO D N 1 ATOM 3275 C CA . PRO D 1 16 ? 122.574 21.841 11.404 1.00 90.01 ? 16 PRO D CA 1 ATOM 3276 C C . PRO D 1 16 ? 123.164 23.072 10.716 1.00 88.54 ? 16 PRO D C 1 ATOM 3277 O O . PRO D 1 16 ? 124.286 23.031 10.212 1.00 87.90 ? 16 PRO D O 1 ATOM 3278 C CB . PRO D 1 16 ? 121.672 21.047 10.463 1.00 90.08 ? 16 PRO D CB 1 ATOM 3279 C CG . PRO D 1 16 ? 120.845 20.269 11.404 1.00 91.59 ? 16 PRO D CG 1 ATOM 3280 C CD . PRO D 1 16 ? 120.463 21.307 12.445 1.00 92.09 ? 16 PRO D CD 1 ATOM 3281 N N . ASP D 1 17 ? 122.420 24.171 10.720 1.00 86.96 ? 17 ASP D N 1 ATOM 3282 C CA . ASP D 1 17 ? 122.863 25.374 10.032 1.00 86.43 ? 17 ASP D CA 1 ATOM 3283 C C . ASP D 1 17 ? 123.144 26.592 10.912 1.00 87.68 ? 17 ASP D C 1 ATOM 3284 O O . ASP D 1 17 ? 123.503 27.660 10.409 1.00 86.54 ? 17 ASP D O 1 ATOM 3285 C CB . ASP D 1 17 ? 121.814 25.723 8.980 1.00 85.30 ? 17 ASP D CB 1 ATOM 3286 C CG . ASP D 1 17 ? 121.175 24.485 8.367 1.00 84.42 ? 17 ASP D CG 1 ATOM 3287 O OD1 . ASP D 1 17 ? 120.532 23.709 9.111 1.00 82.22 ? 17 ASP D OD1 1 ATOM 3288 O OD2 . ASP D 1 17 ? 121.319 24.285 7.143 1.00 84.39 ? 17 ASP D OD2 1 ATOM 3289 N N . GLN D 1 18 ? 122.990 26.430 12.222 1.00 89.37 ? 18 GLN D N 1 ATOM 3290 C CA . GLN D 1 18 ? 123.214 27.524 13.163 1.00 90.59 ? 18 GLN D CA 1 ATOM 3291 C C . GLN D 1 18 ? 122.467 28.794 12.764 1.00 89.75 ? 18 GLN D C 1 ATOM 3292 O O . GLN D 1 18 ? 123.074 29.857 12.629 1.00 90.45 ? 18 GLN D O 1 ATOM 3293 C CB . GLN D 1 18 ? 124.704 27.852 13.278 1.00 94.50 ? 18 GLN D CB 1 ATOM 3294 C CG . GLN D 1 18 ? 125.565 26.744 13.844 1.00 100.66 ? 18 GLN D CG 1 ATOM 3295 C CD . GLN D 1 18 ? 126.852 27.277 14.451 1.00 105.48 ? 18 GLN D CD 1 ATOM 3296 O OE1 . GLN D 1 18 ? 126.851 27.832 15.555 1.00 105.74 ? 18 GLN D OE1 1 ATOM 3297 N NE2 . GLN D 1 18 ? 127.957 27.126 13.725 1.00 108.49 ? 18 GLN D NE2 1 ATOM 3298 N N . SER D 1 19 ? 121.155 28.679 12.561 1.00 88.33 ? 19 SER D N 1 ATOM 3299 C CA . SER D 1 19 ? 120.325 29.828 12.201 1.00 83.30 ? 19 SER D CA 1 ATOM 3300 C C . SER D 1 19 ? 119.123 29.871 13.137 1.00 81.06 ? 19 SER D C 1 ATOM 3301 O O . SER D 1 19 ? 118.508 28.843 13.433 1.00 78.35 ? 19 SER D O 1 ATOM 3302 C CB . SER D 1 19 ? 119.853 29.742 10.739 1.00 81.06 ? 19 SER D CB 1 ATOM 3303 O OG . SER D 1 19 ? 118.884 28.728 10.551 1.00 75.71 ? 19 SER D OG 1 ATOM 3304 N N . GLY D 1 20 ? 118.815 31.068 13.620 1.00 80.36 ? 20 GLY D N 1 ATOM 3305 C CA . GLY D 1 20 ? 117.691 31.241 14.516 1.00 77.88 ? 20 GLY D CA 1 ATOM 3306 C C . GLY D 1 20 ? 116.844 32.413 14.067 1.00 76.52 ? 20 GLY D C 1 ATOM 3307 O O . GLY D 1 20 ? 117.059 32.980 12.990 1.00 78.32 ? 20 GLY D O 1 ATOM 3308 N N . GLU D 1 21 ? 115.873 32.784 14.890 1.00 73.16 ? 21 GLU D N 1 ATOM 3309 C CA . GLU D 1 21 ? 115.008 33.902 14.562 1.00 68.19 ? 21 GLU D CA 1 ATOM 3310 C C . GLU D 1 21 ? 114.221 34.298 15.790 1.00 65.89 ? 21 GLU D C 1 ATOM 3311 O O . GLU D 1 21 ? 113.830 33.448 16.589 1.00 63.82 ? 21 GLU D O 1 ATOM 3312 C CB . GLU D 1 21 ? 114.050 33.520 13.435 1.00 65.55 ? 21 GLU D CB 1 ATOM 3313 C CG . GLU D 1 21 ? 112.991 34.556 13.151 1.00 62.92 ? 21 GLU D CG 1 ATOM 3314 C CD . GLU D 1 21 ? 111.961 34.070 12.150 1.00 63.19 ? 21 GLU D CD 1 ATOM 3315 O OE1 . GLU D 1 21 ? 112.313 33.898 10.961 1.00 60.76 ? 21 GLU D OE1 1 ATOM 3316 O OE2 . GLU D 1 21 ? 110.800 33.855 12.556 1.00 63.82 ? 21 GLU D OE2 1 ATOM 3317 N N . PHE D 1 22 ? 114.019 35.600 15.944 1.00 63.25 ? 22 PHE D N 1 ATOM 3318 C CA . PHE D 1 22 ? 113.258 36.130 17.063 1.00 60.86 ? 22 PHE D CA 1 ATOM 3319 C C . PHE D 1 22 ? 112.296 37.132 16.445 1.00 62.41 ? 22 PHE D C 1 ATOM 3320 O O . PHE D 1 22 ? 112.716 38.025 15.714 1.00 63.45 ? 22 PHE D O 1 ATOM 3321 C CB . PHE D 1 22 ? 114.187 36.818 18.062 1.00 54.56 ? 22 PHE D CB 1 ATOM 3322 C CG . PHE D 1 22 ? 113.505 37.240 19.330 1.00 52.21 ? 22 PHE D CG 1 ATOM 3323 C CD1 . PHE D 1 22 ? 112.572 38.277 19.330 1.00 52.48 ? 22 PHE D CD1 1 ATOM 3324 C CD2 . PHE D 1 22 ? 113.792 36.598 20.533 1.00 51.80 ? 22 PHE D CD2 1 ATOM 3325 C CE1 . PHE D 1 22 ? 111.931 38.671 20.517 1.00 51.85 ? 22 PHE D CE1 1 ATOM 3326 C CE2 . PHE D 1 22 ? 113.159 36.982 21.728 1.00 52.19 ? 22 PHE D CE2 1 ATOM 3327 C CZ . PHE D 1 22 ? 112.227 38.020 21.718 1.00 52.23 ? 22 PHE D CZ 1 ATOM 3328 N N . MET D 1 23 ? 111.003 36.968 16.712 1.00 64.10 ? 23 MET D N 1 ATOM 3329 C CA . MET D 1 23 ? 110.001 37.868 16.154 1.00 64.67 ? 23 MET D CA 1 ATOM 3330 C C . MET D 1 23 ? 108.669 37.829 16.898 1.00 67.00 ? 23 MET D C 1 ATOM 3331 O O . MET D 1 23 ? 108.292 36.810 17.498 1.00 67.73 ? 23 MET D O 1 ATOM 3332 C CB . MET D 1 23 ? 109.776 37.543 14.666 1.00 63.76 ? 23 MET D CB 1 ATOM 3333 C CG . MET D 1 23 ? 109.160 36.174 14.369 1.00 63.13 ? 23 MET D CG 1 ATOM 3334 S SD . MET D 1 23 ? 107.358 36.167 14.399 1.00 61.82 ? 23 MET D SD 1 ATOM 3335 C CE . MET D 1 23 ? 107.005 36.645 12.728 1.00 59.88 ? 23 MET D CE 1 ATOM 3336 N N . PHE D 1 24 ? 107.966 38.957 16.872 1.00 67.72 ? 24 PHE D N 1 ATOM 3337 C CA . PHE D 1 24 ? 106.659 39.047 17.512 1.00 67.83 ? 24 PHE D CA 1 ATOM 3338 C C . PHE D 1 24 ? 105.573 39.000 16.446 1.00 68.22 ? 24 PHE D C 1 ATOM 3339 O O . PHE D 1 24 ? 105.674 39.631 15.385 1.00 65.52 ? 24 PHE D O 1 ATOM 3340 C CB . PHE D 1 24 ? 106.522 40.334 18.327 1.00 65.54 ? 24 PHE D CB 1 ATOM 3341 C CG . PHE D 1 24 ? 106.963 40.200 19.759 1.00 60.20 ? 24 PHE D CG 1 ATOM 3342 C CD1 . PHE D 1 24 ? 108.296 39.966 20.075 1.00 61.15 ? 24 PHE D CD1 1 ATOM 3343 C CD2 . PHE D 1 24 ? 106.042 40.326 20.791 1.00 55.68 ? 24 PHE D CD2 1 ATOM 3344 C CE1 . PHE D 1 24 ? 108.703 39.860 21.401 1.00 60.36 ? 24 PHE D CE1 1 ATOM 3345 C CE2 . PHE D 1 24 ? 106.434 40.222 22.117 1.00 53.81 ? 24 PHE D CE2 1 ATOM 3346 C CZ . PHE D 1 24 ? 107.766 39.989 22.426 1.00 57.27 ? 24 PHE D CZ 1 ATOM 3347 N N . ASP D 1 25 ? 104.534 38.232 16.735 1.00 68.38 ? 25 ASP D N 1 ATOM 3348 C CA . ASP D 1 25 ? 103.433 38.088 15.806 1.00 67.90 ? 25 ASP D CA 1 ATOM 3349 C C . ASP D 1 25 ? 102.139 38.515 16.482 1.00 65.42 ? 25 ASP D C 1 ATOM 3350 O O . ASP D 1 25 ? 101.839 38.111 17.620 1.00 59.91 ? 25 ASP D O 1 ATOM 3351 C CB . ASP D 1 25 ? 103.343 36.628 15.332 1.00 72.86 ? 25 ASP D CB 1 ATOM 3352 C CG . ASP D 1 25 ? 102.109 36.347 14.477 1.00 73.55 ? 25 ASP D CG 1 ATOM 3353 O OD1 . ASP D 1 25 ? 100.976 36.551 14.962 1.00 77.11 ? 25 ASP D OD1 1 ATOM 3354 O OD2 . ASP D 1 25 ? 102.271 35.903 13.321 1.00 72.12 ? 25 ASP D OD2 1 ATOM 3355 N N . PHE D 1 26 ? 101.394 39.359 15.777 1.00 62.11 ? 26 PHE D N 1 ATOM 3356 C CA . PHE D 1 26 ? 100.113 39.837 16.266 1.00 61.11 ? 26 PHE D CA 1 ATOM 3357 C C . PHE D 1 26 ? 99.017 39.325 15.339 1.00 63.27 ? 26 PHE D C 1 ATOM 3358 O O . PHE D 1 26 ? 98.926 39.750 14.176 1.00 65.71 ? 26 PHE D O 1 ATOM 3359 C CB . PHE D 1 26 ? 100.048 41.371 16.288 1.00 54.28 ? 26 PHE D CB 1 ATOM 3360 C CG . PHE D 1 26 ? 98.674 41.901 16.606 1.00 43.36 ? 26 PHE D CG 1 ATOM 3361 C CD1 . PHE D 1 26 ? 98.190 41.882 17.914 1.00 37.48 ? 26 PHE D CD1 1 ATOM 3362 C CD2 . PHE D 1 26 ? 97.823 42.311 15.584 1.00 36.09 ? 26 PHE D CD2 1 ATOM 3363 C CE1 . PHE D 1 26 ? 96.877 42.257 18.192 1.00 31.52 ? 26 PHE D CE1 1 ATOM 3364 C CE2 . PHE D 1 26 ? 96.511 42.683 15.855 1.00 29.81 ? 26 PHE D CE2 1 ATOM 3365 C CZ . PHE D 1 26 ? 96.037 42.655 17.158 1.00 26.95 ? 26 PHE D CZ 1 ATOM 3366 N N . ASP D 1 27 ? 98.188 38.416 15.846 1.00 61.64 ? 27 ASP D N 1 ATOM 3367 C CA . ASP D 1 27 ? 97.093 37.876 15.051 1.00 61.97 ? 27 ASP D CA 1 ATOM 3368 C C . ASP D 1 27 ? 97.504 37.505 13.626 1.00 61.48 ? 27 ASP D C 1 ATOM 3369 O O . ASP D 1 27 ? 96.851 37.905 12.661 1.00 61.24 ? 27 ASP D O 1 ATOM 3370 C CB . ASP D 1 27 ? 95.951 38.889 14.996 1.00 65.11 ? 27 ASP D CB 1 ATOM 3371 C CG . ASP D 1 27 ? 95.089 38.868 16.239 1.00 69.55 ? 27 ASP D CG 1 ATOM 3372 O OD1 . ASP D 1 27 ? 95.629 38.698 17.356 1.00 73.22 ? 27 ASP D OD1 1 ATOM 3373 O OD2 . ASP D 1 27 ? 93.863 39.034 16.092 1.00 70.79 ? 27 ASP D OD2 1 ATOM 3374 N N . GLY D 1 28 ? 98.596 36.760 13.492 1.00 60.66 ? 28 GLY D N 1 ATOM 3375 C CA . GLY D 1 28 ? 99.032 36.332 12.175 1.00 60.14 ? 28 GLY D CA 1 ATOM 3376 C C . GLY D 1 28 ? 100.053 37.167 11.427 1.00 59.78 ? 28 GLY D C 1 ATOM 3377 O O . GLY D 1 28 ? 100.846 36.621 10.656 1.00 58.03 ? 28 GLY D O 1 ATOM 3378 N N . ASP D 1 29 ? 100.032 38.481 11.621 1.00 60.40 ? 29 ASP D N 1 ATOM 3379 C CA . ASP D 1 29 ? 100.985 39.344 10.937 1.00 62.16 ? 29 ASP D CA 1 ATOM 3380 C C . ASP D 1 29 ? 102.198 39.631 11.839 1.00 64.87 ? 29 ASP D C 1 ATOM 3381 O O . ASP D 1 29 ? 102.098 39.581 13.076 1.00 64.17 ? 29 ASP D O 1 ATOM 3382 C CB . ASP D 1 29 ? 100.299 40.652 10.516 1.00 62.44 ? 29 ASP D CB 1 ATOM 3383 C CG . ASP D 1 29 ? 99.335 40.476 9.332 1.00 61.57 ? 29 ASP D CG 1 ATOM 3384 O OD1 . ASP D 1 29 ? 99.794 40.214 8.192 1.00 58.18 ? 29 ASP D OD1 1 ATOM 3385 O OD2 . ASP D 1 29 ? 98.111 40.611 9.544 1.00 61.68 ? 29 ASP D OD2 1 ATOM 3386 N N . GLU D 1 30 ? 103.342 39.914 11.213 1.00 65.35 ? 30 GLU D N 1 ATOM 3387 C CA . GLU D 1 30 ? 104.587 40.202 11.931 1.00 66.01 ? 30 GLU D CA 1 ATOM 3388 C C . GLU D 1 30 ? 104.628 41.638 12.433 1.00 66.80 ? 30 GLU D C 1 ATOM 3389 O O . GLU D 1 30 ? 104.312 42.561 11.689 1.00 66.56 ? 30 GLU D O 1 ATOM 3390 C CB . GLU D 1 30 ? 105.790 39.996 11.008 1.00 65.85 ? 30 GLU D CB 1 ATOM 3391 C CG . GLU D 1 30 ? 107.135 40.266 11.680 1.00 70.32 ? 30 GLU D CG 1 ATOM 3392 C CD . GLU D 1 30 ? 108.272 40.543 10.690 1.00 74.32 ? 30 GLU D CD 1 ATOM 3393 O OE1 . GLU D 1 30 ? 108.300 39.923 9.599 1.00 75.17 ? 30 GLU D OE1 1 ATOM 3394 O OE2 . GLU D 1 30 ? 109.152 41.377 11.014 1.00 73.20 ? 30 GLU D OE2 1 ATOM 3395 N N . ILE D 1 31 ? 105.016 41.833 13.691 1.00 67.22 ? 31 ILE D N 1 ATOM 3396 C CA . ILE D 1 31 ? 105.131 43.185 14.235 1.00 64.37 ? 31 ILE D CA 1 ATOM 3397 C C . ILE D 1 31 ? 106.559 43.613 13.940 1.00 64.24 ? 31 ILE D C 1 ATOM 3398 O O . ILE D 1 31 ? 106.799 44.644 13.312 1.00 64.10 ? 31 ILE D O 1 ATOM 3399 C CB . ILE D 1 31 ? 104.929 43.227 15.756 1.00 62.01 ? 31 ILE D CB 1 ATOM 3400 C CG1 . ILE D 1 31 ? 103.498 42.839 16.113 1.00 58.86 ? 31 ILE D CG1 1 ATOM 3401 C CG2 . ILE D 1 31 ? 105.226 44.626 16.273 1.00 63.10 ? 31 ILE D CG2 1 ATOM 3402 C CD1 . ILE D 1 31 ? 103.248 42.843 17.603 1.00 55.48 ? 31 ILE D CD1 1 ATOM 3403 N N . PHE D 1 32 ? 107.501 42.795 14.399 1.00 64.59 ? 32 PHE D N 1 ATOM 3404 C CA . PHE D 1 32 ? 108.926 43.035 14.189 1.00 65.58 ? 32 PHE D CA 1 ATOM 3405 C C . PHE D 1 32 ? 109.707 41.741 14.436 1.00 67.01 ? 32 PHE D C 1 ATOM 3406 O O . PHE D 1 32 ? 109.136 40.719 14.824 1.00 68.59 ? 32 PHE D O 1 ATOM 3407 C CB . PHE D 1 32 ? 109.449 44.105 15.151 1.00 61.44 ? 32 PHE D CB 1 ATOM 3408 C CG . PHE D 1 32 ? 109.666 43.602 16.546 1.00 57.09 ? 32 PHE D CG 1 ATOM 3409 C CD1 . PHE D 1 32 ? 108.636 43.616 17.472 1.00 57.35 ? 32 PHE D CD1 1 ATOM 3410 C CD2 . PHE D 1 32 ? 110.891 43.066 16.917 1.00 55.11 ? 32 PHE D CD2 1 ATOM 3411 C CE1 . PHE D 1 32 ? 108.825 43.099 18.752 1.00 58.26 ? 32 PHE D CE1 1 ATOM 3412 C CE2 . PHE D 1 32 ? 111.086 42.547 18.189 1.00 56.50 ? 32 PHE D CE2 1 ATOM 3413 C CZ . PHE D 1 32 ? 110.053 42.563 19.109 1.00 55.66 ? 32 PHE D CZ 1 ATOM 3414 N N . HIS D 1 33 ? 111.018 41.800 14.228 1.00 66.11 ? 33 HIS D N 1 ATOM 3415 C CA . HIS D 1 33 ? 111.885 40.651 14.448 1.00 65.59 ? 33 HIS D CA 1 ATOM 3416 C C . HIS D 1 33 ? 113.328 41.128 14.531 1.00 67.81 ? 33 HIS D C 1 ATOM 3417 O O . HIS D 1 33 ? 113.729 42.020 13.790 1.00 70.42 ? 33 HIS D O 1 ATOM 3418 C CB . HIS D 1 33 ? 111.766 39.660 13.298 1.00 60.59 ? 33 HIS D CB 1 ATOM 3419 C CG . HIS D 1 33 ? 112.359 40.157 12.022 1.00 59.68 ? 33 HIS D CG 1 ATOM 3420 N ND1 . HIS D 1 33 ? 111.689 41.009 11.171 1.00 60.21 ? 33 HIS D ND1 1 ATOM 3421 C CD2 . HIS D 1 33 ? 113.578 39.952 11.469 1.00 60.24 ? 33 HIS D CD2 1 ATOM 3422 C CE1 . HIS D 1 33 ? 112.470 41.304 10.146 1.00 62.39 ? 33 HIS D CE1 1 ATOM 3423 N NE2 . HIS D 1 33 ? 113.622 40.676 10.302 1.00 60.69 ? 33 HIS D NE2 1 ATOM 3424 N N . VAL D 1 34 ? 114.113 40.534 15.423 1.00 70.06 ? 34 VAL D N 1 ATOM 3425 C CA . VAL D 1 34 ? 115.514 40.920 15.561 1.00 70.05 ? 34 VAL D CA 1 ATOM 3426 C C . VAL D 1 34 ? 116.371 40.303 14.467 1.00 72.94 ? 34 VAL D C 1 ATOM 3427 O O . VAL D 1 34 ? 116.422 39.083 14.327 1.00 72.81 ? 34 VAL D O 1 ATOM 3428 C CB . VAL D 1 34 ? 116.084 40.478 16.912 1.00 67.06 ? 34 VAL D CB 1 ATOM 3429 C CG1 . VAL D 1 34 ? 117.560 40.849 16.997 1.00 64.21 ? 34 VAL D CG1 1 ATOM 3430 C CG2 . VAL D 1 34 ? 115.287 41.115 18.035 1.00 63.72 ? 34 VAL D CG2 1 ATOM 3431 N N . ASP D 1 35 ? 117.035 41.153 13.689 1.00 78.11 ? 35 ASP D N 1 ATOM 3432 C CA . ASP D 1 35 ? 117.909 40.691 12.616 1.00 84.58 ? 35 ASP D CA 1 ATOM 3433 C C . ASP D 1 35 ? 119.230 40.283 13.255 1.00 88.08 ? 35 ASP D C 1 ATOM 3434 O O . ASP D 1 35 ? 120.037 41.135 13.630 1.00 87.97 ? 35 ASP D O 1 ATOM 3435 C CB . ASP D 1 35 ? 118.157 41.808 11.598 1.00 85.98 ? 35 ASP D CB 1 ATOM 3436 C CG . ASP D 1 35 ? 119.004 41.347 10.418 1.00 88.35 ? 35 ASP D CG 1 ATOM 3437 O OD1 . ASP D 1 35 ? 120.067 40.729 10.645 1.00 87.42 ? 35 ASP D OD1 1 ATOM 3438 O OD2 . ASP D 1 35 ? 118.612 41.607 9.260 1.00 90.97 ? 35 ASP D OD2 1 ATOM 3439 N N . MET D 1 36 ? 119.438 38.978 13.379 1.00 92.49 ? 36 MET D N 1 ATOM 3440 C CA . MET D 1 36 ? 120.644 38.430 13.988 1.00 96.88 ? 36 MET D CA 1 ATOM 3441 C C . MET D 1 36 ? 121.934 39.149 13.569 1.00 99.34 ? 36 MET D C 1 ATOM 3442 O O . MET D 1 36 ? 122.597 39.787 14.396 1.00 99.82 ? 36 MET D O 1 ATOM 3443 C CB . MET D 1 36 ? 120.749 36.935 13.659 1.00 97.85 ? 36 MET D CB 1 ATOM 3444 C CG . MET D 1 36 ? 119.536 36.108 14.082 1.00 98.75 ? 36 MET D CG 1 ATOM 3445 S SD . MET D 1 36 ? 119.145 36.235 15.845 1.00 99.89 ? 36 MET D SD 1 ATOM 3446 C CE . MET D 1 36 ? 120.492 35.299 16.549 1.00 97.92 ? 36 MET D CE 1 ATOM 3447 N N . ALA D 1 37 ? 122.280 39.038 12.286 1.00 100.91 ? 37 ALA D N 1 ATOM 3448 C CA . ALA D 1 37 ? 123.487 39.657 11.731 1.00 100.77 ? 37 ALA D CA 1 ATOM 3449 C C . ALA D 1 37 ? 123.654 41.126 12.130 1.00 101.13 ? 37 ALA D C 1 ATOM 3450 O O . ALA D 1 37 ? 124.476 41.459 12.987 1.00 101.18 ? 37 ALA D O 1 ATOM 3451 C CB . ALA D 1 37 ? 123.477 39.530 10.204 1.00 100.40 ? 37 ALA D CB 1 ATOM 3452 N N . LYS D 1 38 ? 122.873 42.000 11.504 1.00 100.91 ? 38 LYS D N 1 ATOM 3453 C CA . LYS D 1 38 ? 122.939 43.427 11.794 1.00 100.25 ? 38 LYS D CA 1 ATOM 3454 C C . LYS D 1 38 ? 122.801 43.724 13.289 1.00 99.16 ? 38 LYS D C 1 ATOM 3455 O O . LYS D 1 38 ? 123.075 44.840 13.725 1.00 99.46 ? 38 LYS D O 1 ATOM 3456 C CB . LYS D 1 38 ? 121.862 44.171 11.001 1.00 101.45 ? 38 LYS D CB 1 ATOM 3457 C CG . LYS D 1 38 ? 121.937 43.923 9.499 1.00 103.15 ? 38 LYS D CG 1 ATOM 3458 C CD . LYS D 1 38 ? 120.833 44.661 8.751 1.00 105.29 ? 38 LYS D CD 1 ATOM 3459 C CE . LYS D 1 38 ? 120.726 44.200 7.298 1.00 105.65 ? 38 LYS D CE 1 ATOM 3460 N NZ . LYS D 1 38 ? 120.340 42.760 7.174 1.00 102.77 ? 38 LYS D NZ 1 ATOM 3461 N N . LYS D 1 39 ? 122.367 42.734 14.067 1.00 97.68 ? 39 LYS D N 1 ATOM 3462 C CA . LYS D 1 39 ? 122.239 42.899 15.514 1.00 97.94 ? 39 LYS D CA 1 ATOM 3463 C C . LYS D 1 39 ? 121.128 43.886 15.910 1.00 99.13 ? 39 LYS D C 1 ATOM 3464 O O . LYS D 1 39 ? 120.990 44.234 17.089 1.00 97.33 ? 39 LYS D O 1 ATOM 3465 C CB . LYS D 1 39 ? 123.593 43.375 16.069 1.00 96.64 ? 39 LYS D CB 1 ATOM 3466 C CG . LYS D 1 39 ? 123.762 43.320 17.577 1.00 96.52 ? 39 LYS D CG 1 ATOM 3467 C CD . LYS D 1 39 ? 123.954 41.899 18.069 1.00 98.05 ? 39 LYS D CD 1 ATOM 3468 C CE . LYS D 1 39 ? 125.151 41.212 17.428 1.00 98.95 ? 39 LYS D CE 1 ATOM 3469 N NZ . LYS D 1 39 ? 125.259 39.792 17.877 1.00 98.02 ? 39 LYS D NZ 1 ATOM 3470 N N . GLU D 1 40 ? 120.330 44.324 14.936 1.00 100.49 ? 40 GLU D N 1 ATOM 3471 C CA . GLU D 1 40 ? 119.261 45.282 15.217 1.00 100.72 ? 40 GLU D CA 1 ATOM 3472 C C . GLU D 1 40 ? 117.832 44.801 14.926 1.00 97.53 ? 40 GLU D C 1 ATOM 3473 O O . GLU D 1 40 ? 117.611 43.922 14.093 1.00 97.93 ? 40 GLU D O 1 ATOM 3474 C CB . GLU D 1 40 ? 119.521 46.589 14.462 1.00 105.21 ? 40 GLU D CB 1 ATOM 3475 C CG . GLU D 1 40 ? 118.705 47.756 14.999 1.00 113.76 ? 40 GLU D CG 1 ATOM 3476 C CD . GLU D 1 40 ? 118.843 47.916 16.515 1.00 119.46 ? 40 GLU D CD 1 ATOM 3477 O OE1 . GLU D 1 40 ? 119.976 48.154 16.991 1.00 122.80 ? 40 GLU D OE1 1 ATOM 3478 O OE2 . GLU D 1 40 ? 117.819 47.801 17.230 1.00 120.28 ? 40 GLU D OE2 1 ATOM 3479 N N . THR D 1 41 ? 116.874 45.400 15.631 1.00 93.18 ? 41 THR D N 1 ATOM 3480 C CA . THR D 1 41 ? 115.446 45.097 15.509 1.00 88.61 ? 41 THR D CA 1 ATOM 3481 C C . THR D 1 41 ? 114.845 45.678 14.224 1.00 87.49 ? 41 THR D C 1 ATOM 3482 O O . THR D 1 41 ? 115.070 46.841 13.910 1.00 88.60 ? 41 THR D O 1 ATOM 3483 C CB . THR D 1 41 ? 114.666 45.702 16.708 1.00 87.48 ? 41 THR D CB 1 ATOM 3484 O OG1 . THR D 1 41 ? 115.034 45.026 17.918 1.00 84.78 ? 41 THR D OG1 1 ATOM 3485 C CG2 . THR D 1 41 ? 113.160 45.607 16.481 1.00 85.24 ? 41 THR D CG2 1 ATOM 3486 N N . VAL D 1 42 ? 114.070 44.880 13.493 1.00 86.57 ? 42 VAL D N 1 ATOM 3487 C CA . VAL D 1 42 ? 113.440 45.340 12.250 1.00 84.46 ? 42 VAL D CA 1 ATOM 3488 C C . VAL D 1 42 ? 111.917 45.331 12.377 1.00 84.92 ? 42 VAL D C 1 ATOM 3489 O O . VAL D 1 42 ? 111.331 44.334 12.802 1.00 86.54 ? 42 VAL D O 1 ATOM 3490 C CB . VAL D 1 42 ? 113.821 44.437 11.042 1.00 82.12 ? 42 VAL D CB 1 ATOM 3491 C CG1 . VAL D 1 42 ? 113.214 44.992 9.765 1.00 78.89 ? 42 VAL D CG1 1 ATOM 3492 C CG2 . VAL D 1 42 ? 115.330 44.331 10.915 1.00 81.46 ? 42 VAL D CG2 1 ATOM 3493 N N . TRP D 1 43 ? 111.275 46.434 12.006 1.00 83.93 ? 43 TRP D N 1 ATOM 3494 C CA . TRP D 1 43 ? 109.819 46.508 12.080 1.00 81.95 ? 43 TRP D CA 1 ATOM 3495 C C . TRP D 1 43 ? 109.199 46.257 10.716 1.00 81.43 ? 43 TRP D C 1 ATOM 3496 O O . TRP D 1 43 ? 109.750 46.661 9.697 1.00 80.16 ? 43 TRP D O 1 ATOM 3497 C CB . TRP D 1 43 ? 109.374 47.870 12.610 1.00 79.38 ? 43 TRP D CB 1 ATOM 3498 C CG . TRP D 1 43 ? 109.922 48.157 13.962 1.00 77.38 ? 43 TRP D CG 1 ATOM 3499 C CD1 . TRP D 1 43 ? 111.174 48.607 14.257 1.00 77.60 ? 43 TRP D CD1 1 ATOM 3500 C CD2 . TRP D 1 43 ? 109.254 47.970 15.216 1.00 77.17 ? 43 TRP D CD2 1 ATOM 3501 N NE1 . TRP D 1 43 ? 111.331 48.713 15.618 1.00 79.53 ? 43 TRP D NE1 1 ATOM 3502 C CE2 . TRP D 1 43 ? 110.168 48.328 16.231 1.00 78.26 ? 43 TRP D CE2 1 ATOM 3503 C CE3 . TRP D 1 43 ? 107.972 47.532 15.581 1.00 75.71 ? 43 TRP D CE3 1 ATOM 3504 C CZ2 . TRP D 1 43 ? 109.841 48.262 17.592 1.00 77.90 ? 43 TRP D CZ2 1 ATOM 3505 C CZ3 . TRP D 1 43 ? 107.647 47.466 16.937 1.00 73.95 ? 43 TRP D CZ3 1 ATOM 3506 C CH2 . TRP D 1 43 ? 108.580 47.829 17.923 1.00 74.81 ? 43 TRP D CH2 1 ATOM 3507 N N . ARG D 1 44 ? 108.057 45.577 10.703 1.00 81.36 ? 44 ARG D N 1 ATOM 3508 C CA . ARG D 1 44 ? 107.368 45.269 9.458 1.00 81.81 ? 44 ARG D CA 1 ATOM 3509 C C . ARG D 1 44 ? 106.881 46.553 8.784 1.00 83.81 ? 44 ARG D C 1 ATOM 3510 O O . ARG D 1 44 ? 106.933 46.691 7.557 1.00 81.89 ? 44 ARG D O 1 ATOM 3511 C CB . ARG D 1 44 ? 106.178 44.350 9.733 1.00 79.83 ? 44 ARG D CB 1 ATOM 3512 C CG . ARG D 1 44 ? 105.525 43.791 8.476 1.00 77.14 ? 44 ARG D CG 1 ATOM 3513 C CD . ARG D 1 44 ? 106.387 42.718 7.829 1.00 73.64 ? 44 ARG D CD 1 ATOM 3514 N NE . ARG D 1 44 ? 105.807 42.222 6.585 1.00 72.04 ? 44 ARG D NE 1 ATOM 3515 C CZ . ARG D 1 44 ? 105.877 42.860 5.422 1.00 73.27 ? 44 ARG D CZ 1 ATOM 3516 N NH1 . ARG D 1 44 ? 106.510 44.024 5.338 1.00 71.88 ? 44 ARG D NH1 1 ATOM 3517 N NH2 . ARG D 1 44 ? 105.307 42.337 4.342 1.00 74.45 ? 44 ARG D NH2 1 ATOM 3518 N N . LEU D 1 45 ? 106.402 47.489 9.598 1.00 86.59 ? 45 LEU D N 1 ATOM 3519 C CA . LEU D 1 45 ? 105.914 48.765 9.090 1.00 89.37 ? 45 LEU D CA 1 ATOM 3520 C C . LEU D 1 45 ? 106.616 49.918 9.797 1.00 90.91 ? 45 LEU D C 1 ATOM 3521 O O . LEU D 1 45 ? 106.635 49.984 11.028 1.00 90.12 ? 45 LEU D O 1 ATOM 3522 C CB . LEU D 1 45 ? 104.400 48.884 9.297 1.00 89.87 ? 45 LEU D CB 1 ATOM 3523 C CG . LEU D 1 45 ? 103.509 47.795 8.694 1.00 87.03 ? 45 LEU D CG 1 ATOM 3524 C CD1 . LEU D 1 45 ? 102.064 48.280 8.659 1.00 82.93 ? 45 LEU D CD1 1 ATOM 3525 C CD2 . LEU D 1 45 ? 103.990 47.465 7.287 1.00 88.26 ? 45 LEU D CD2 1 ATOM 3526 N N . GLU D 1 46 ? 107.197 50.816 9.008 1.00 92.69 ? 46 GLU D N 1 ATOM 3527 C CA . GLU D 1 46 ? 107.900 51.972 9.546 1.00 94.63 ? 46 GLU D CA 1 ATOM 3528 C C . GLU D 1 46 ? 107.158 52.502 10.759 1.00 92.85 ? 46 GLU D C 1 ATOM 3529 O O . GLU D 1 46 ? 107.705 52.575 11.863 1.00 90.33 ? 46 GLU D O 1 ATOM 3530 C CB . GLU D 1 46 ? 107.982 53.069 8.487 1.00 99.92 ? 46 GLU D CB 1 ATOM 3531 C CG . GLU D 1 46 ? 108.945 52.774 7.352 1.00 107.67 ? 46 GLU D CG 1 ATOM 3532 C CD . GLU D 1 46 ? 108.903 53.839 6.268 1.00 113.49 ? 46 GLU D CD 1 ATOM 3533 O OE1 . GLU D 1 46 ? 108.972 55.042 6.605 1.00 116.63 ? 46 GLU D OE1 1 ATOM 3534 O OE2 . GLU D 1 46 ? 108.805 53.472 5.078 1.00 114.85 ? 46 GLU D OE2 1 ATOM 3535 N N . GLU D 1 47 ? 105.901 52.861 10.531 1.00 91.35 ? 47 GLU D N 1 ATOM 3536 C CA . GLU D 1 47 ? 105.035 53.395 11.569 1.00 92.71 ? 47 GLU D CA 1 ATOM 3537 C C . GLU D 1 47 ? 105.183 52.725 12.936 1.00 91.32 ? 47 GLU D C 1 ATOM 3538 O O . GLU D 1 47 ? 105.286 53.397 13.956 1.00 89.66 ? 47 GLU D O 1 ATOM 3539 C CB . GLU D 1 47 ? 103.584 53.284 11.118 1.00 97.87 ? 47 GLU D CB 1 ATOM 3540 C CG . GLU D 1 47 ? 102.588 53.443 12.249 1.00 105.73 ? 47 GLU D CG 1 ATOM 3541 C CD . GLU D 1 47 ? 101.195 52.983 11.864 1.00 112.31 ? 47 GLU D CD 1 ATOM 3542 O OE1 . GLU D 1 47 ? 100.332 52.891 12.769 1.00 115.34 ? 47 GLU D OE1 1 ATOM 3543 O OE2 . GLU D 1 47 ? 100.968 52.718 10.659 1.00 114.06 ? 47 GLU D OE2 1 ATOM 3544 N N . PHE D 1 48 ? 105.175 51.399 12.947 1.00 92.50 ? 48 PHE D N 1 ATOM 3545 C CA . PHE D 1 48 ? 105.286 50.625 14.183 1.00 92.52 ? 48 PHE D CA 1 ATOM 3546 C C . PHE D 1 48 ? 106.425 51.096 15.072 1.00 93.70 ? 48 PHE D C 1 ATOM 3547 O O . PHE D 1 48 ? 106.252 51.274 16.281 1.00 92.33 ? 48 PHE D O 1 ATOM 3548 C CB . PHE D 1 48 ? 105.505 49.143 13.857 1.00 90.46 ? 48 PHE D CB 1 ATOM 3549 C CG . PHE D 1 48 ? 104.347 48.489 13.161 1.00 86.18 ? 48 PHE D CG 1 ATOM 3550 C CD1 . PHE D 1 48 ? 103.357 49.250 12.547 1.00 83.34 ? 48 PHE D CD1 1 ATOM 3551 C CD2 . PHE D 1 48 ? 104.260 47.109 13.102 1.00 84.70 ? 48 PHE D CD2 1 ATOM 3552 C CE1 . PHE D 1 48 ? 102.303 48.649 11.889 1.00 80.07 ? 48 PHE D CE1 1 ATOM 3553 C CE2 . PHE D 1 48 ? 103.211 46.502 12.445 1.00 83.86 ? 48 PHE D CE2 1 ATOM 3554 C CZ . PHE D 1 48 ? 102.228 47.276 11.836 1.00 82.01 ? 48 PHE D CZ 1 ATOM 3555 N N . GLY D 1 49 ? 107.591 51.283 14.457 1.00 95.08 ? 49 GLY D N 1 ATOM 3556 C CA . GLY D 1 49 ? 108.775 51.703 15.186 1.00 95.94 ? 49 GLY D CA 1 ATOM 3557 C C . GLY D 1 49 ? 108.639 53.036 15.883 1.00 95.94 ? 49 GLY D C 1 ATOM 3558 O O . GLY D 1 49 ? 109.000 53.178 17.051 1.00 95.12 ? 49 GLY D O 1 ATOM 3559 N N . ARG D 1 50 ? 108.109 54.015 15.164 1.00 96.46 ? 50 ARG D N 1 ATOM 3560 C CA . ARG D 1 50 ? 107.934 55.348 15.709 1.00 98.19 ? 50 ARG D CA 1 ATOM 3561 C C . ARG D 1 50 ? 107.003 55.353 16.920 1.00 98.51 ? 50 ARG D C 1 ATOM 3562 O O . ARG D 1 50 ? 106.866 56.373 17.588 1.00 100.73 ? 50 ARG D O 1 ATOM 3563 C CB . ARG D 1 50 ? 107.369 56.279 14.634 1.00 99.96 ? 50 ARG D CB 1 ATOM 3564 C CG . ARG D 1 50 ? 107.638 57.752 14.890 1.00 105.05 ? 50 ARG D CG 1 ATOM 3565 C CD . ARG D 1 50 ? 106.545 58.665 14.337 1.00 109.06 ? 50 ARG D CD 1 ATOM 3566 N NE . ARG D 1 50 ? 106.285 58.480 12.911 1.00 111.30 ? 50 ARG D NE 1 ATOM 3567 C CZ . ARG D 1 50 ? 105.487 57.544 12.406 1.00 112.55 ? 50 ARG D CZ 1 ATOM 3568 N NH1 . ARG D 1 50 ? 104.862 56.695 13.209 1.00 113.74 ? 50 ARG D NH1 1 ATOM 3569 N NH2 . ARG D 1 50 ? 105.305 57.459 11.095 1.00 112.29 ? 50 ARG D NH2 1 ATOM 3570 N N . PHE D 1 51 ? 106.373 54.219 17.208 1.00 99.06 ? 51 PHE D N 1 ATOM 3571 C CA . PHE D 1 51 ? 105.434 54.126 18.329 1.00 100.45 ? 51 PHE D CA 1 ATOM 3572 C C . PHE D 1 51 ? 105.937 53.321 19.513 1.00 99.75 ? 51 PHE D C 1 ATOM 3573 O O . PHE D 1 51 ? 105.391 53.423 20.609 1.00 98.73 ? 51 PHE D O 1 ATOM 3574 C CB . PHE D 1 51 ? 104.120 53.479 17.881 1.00 104.64 ? 51 PHE D CB 1 ATOM 3575 C CG . PHE D 1 51 ? 103.371 54.254 16.839 1.00 110.20 ? 51 PHE D CG 1 ATOM 3576 C CD1 . PHE D 1 51 ? 102.172 53.757 16.331 1.00 113.00 ? 51 PHE D CD1 1 ATOM 3577 C CD2 . PHE D 1 51 ? 103.849 55.473 16.362 1.00 111.77 ? 51 PHE D CD2 1 ATOM 3578 C CE1 . PHE D 1 51 ? 101.457 54.459 15.362 1.00 114.93 ? 51 PHE D CE1 1 ATOM 3579 C CE2 . PHE D 1 51 ? 103.143 56.185 15.394 1.00 113.83 ? 51 PHE D CE2 1 ATOM 3580 C CZ . PHE D 1 51 ? 101.944 55.677 14.891 1.00 115.23 ? 51 PHE D CZ 1 ATOM 3581 N N . ALA D 1 52 ? 106.948 52.493 19.291 1.00 99.20 ? 52 ALA D N 1 ATOM 3582 C CA . ALA D 1 52 ? 107.475 51.675 20.372 1.00 98.38 ? 52 ALA D CA 1 ATOM 3583 C C . ALA D 1 52 ? 108.856 51.147 20.042 1.00 97.46 ? 52 ALA D C 1 ATOM 3584 O O . ALA D 1 52 ? 109.357 51.329 18.929 1.00 95.05 ? 52 ALA D O 1 ATOM 3585 C CB . ALA D 1 52 ? 106.523 50.515 20.664 1.00 98.67 ? 52 ALA D CB 1 ATOM 3586 N N . SER D 1 53 ? 109.485 50.506 21.018 1.00 97.87 ? 53 SER D N 1 ATOM 3587 C CA . SER D 1 53 ? 110.799 49.952 20.772 1.00 99.21 ? 53 SER D CA 1 ATOM 3588 C C . SER D 1 53 ? 111.088 48.679 21.551 1.00 98.41 ? 53 SER D C 1 ATOM 3589 O O . SER D 1 53 ? 110.343 48.284 22.455 1.00 96.06 ? 53 SER D O 1 ATOM 3590 C CB . SER D 1 53 ? 111.886 50.991 21.038 1.00 101.04 ? 53 SER D CB 1 ATOM 3591 O OG . SER D 1 53 ? 113.053 50.668 20.293 1.00 103.63 ? 53 SER D OG 1 ATOM 3592 N N . PHE D 1 54 ? 112.187 48.040 21.165 1.00 98.30 ? 54 PHE D N 1 ATOM 3593 C CA . PHE D 1 54 ? 112.628 46.793 21.759 1.00 98.19 ? 54 PHE D CA 1 ATOM 3594 C C . PHE D 1 54 ? 114.148 46.717 21.631 1.00 99.59 ? 54 PHE D C 1 ATOM 3595 O O . PHE D 1 54 ? 114.719 47.123 20.611 1.00 99.60 ? 54 PHE D O 1 ATOM 3596 C CB . PHE D 1 54 ? 111.975 45.628 21.018 1.00 96.36 ? 54 PHE D CB 1 ATOM 3597 C CG . PHE D 1 54 ? 112.285 44.292 21.600 1.00 94.18 ? 54 PHE D CG 1 ATOM 3598 C CD1 . PHE D 1 54 ? 111.915 43.987 22.902 1.00 95.20 ? 54 PHE D CD1 1 ATOM 3599 C CD2 . PHE D 1 54 ? 112.943 43.330 20.843 1.00 93.21 ? 54 PHE D CD2 1 ATOM 3600 C CE1 . PHE D 1 54 ? 112.196 42.738 23.447 1.00 96.59 ? 54 PHE D CE1 1 ATOM 3601 C CE2 . PHE D 1 54 ? 113.230 42.079 21.374 1.00 94.12 ? 54 PHE D CE2 1 ATOM 3602 C CZ . PHE D 1 54 ? 112.856 41.781 22.680 1.00 95.90 ? 54 PHE D CZ 1 ATOM 3603 N N . GLU D 1 55 ? 114.803 46.204 22.667 1.00 99.88 ? 55 GLU D N 1 ATOM 3604 C CA . GLU D 1 55 ? 116.256 46.097 22.649 1.00 99.81 ? 55 GLU D CA 1 ATOM 3605 C C . GLU D 1 55 ? 116.738 44.838 21.938 1.00 97.30 ? 55 GLU D C 1 ATOM 3606 O O . GLU D 1 55 ? 116.818 43.764 22.540 1.00 96.31 ? 55 GLU D O 1 ATOM 3607 C CB . GLU D 1 55 ? 116.816 46.128 24.076 1.00 103.52 ? 55 GLU D CB 1 ATOM 3608 C CG . GLU D 1 55 ? 117.823 47.255 24.299 1.00 106.88 ? 55 GLU D CG 1 ATOM 3609 C CD . GLU D 1 55 ? 118.893 47.315 23.211 1.00 108.85 ? 55 GLU D CD 1 ATOM 3610 O OE1 . GLU D 1 55 ? 119.797 46.446 23.201 1.00 109.94 ? 55 GLU D OE1 1 ATOM 3611 O OE2 . GLU D 1 55 ? 118.822 48.228 22.359 1.00 107.99 ? 55 GLU D OE2 1 ATOM 3612 N N . ALA D 1 56 ? 117.065 44.986 20.657 1.00 94.15 ? 56 ALA D N 1 ATOM 3613 C CA . ALA D 1 56 ? 117.547 43.876 19.845 1.00 92.56 ? 56 ALA D CA 1 ATOM 3614 C C . ALA D 1 56 ? 118.423 42.924 20.653 1.00 91.15 ? 56 ALA D C 1 ATOM 3615 O O . ALA D 1 56 ? 118.251 41.708 20.597 1.00 91.41 ? 56 ALA D O 1 ATOM 3616 C CB . ALA D 1 56 ? 118.330 44.409 18.641 1.00 91.31 ? 56 ALA D CB 1 ATOM 3617 N N . GLN D 1 57 ? 119.355 43.483 21.413 1.00 89.84 ? 57 GLN D N 1 ATOM 3618 C CA . GLN D 1 57 ? 120.261 42.674 22.212 1.00 90.00 ? 57 GLN D CA 1 ATOM 3619 C C . GLN D 1 57 ? 119.557 41.570 23.005 1.00 87.03 ? 57 GLN D C 1 ATOM 3620 O O . GLN D 1 57 ? 119.805 40.386 22.769 1.00 86.08 ? 57 GLN D O 1 ATOM 3621 C CB . GLN D 1 57 ? 121.071 43.577 23.157 1.00 94.25 ? 57 GLN D CB 1 ATOM 3622 C CG . GLN D 1 57 ? 122.263 42.887 23.842 1.00 98.78 ? 57 GLN D CG 1 ATOM 3623 C CD . GLN D 1 57 ? 121.930 42.299 25.213 1.00 98.96 ? 57 GLN D CD 1 ATOM 3624 O OE1 . GLN D 1 57 ? 120.958 41.558 25.374 1.00 99.09 ? 57 GLN D OE1 1 ATOM 3625 N NE2 . GLN D 1 57 ? 122.752 42.625 26.205 1.00 98.79 ? 57 GLN D NE2 1 ATOM 3626 N N . GLY D 1 58 ? 118.682 41.960 23.932 1.00 85.11 ? 58 GLY D N 1 ATOM 3627 C CA . GLY D 1 58 ? 117.966 40.996 24.764 1.00 84.00 ? 58 GLY D CA 1 ATOM 3628 C C . GLY D 1 58 ? 117.468 39.746 24.056 1.00 83.39 ? 58 GLY D C 1 ATOM 3629 O O . GLY D 1 58 ? 117.349 38.674 24.659 1.00 79.55 ? 58 GLY D O 1 ATOM 3630 N N . ALA D 1 59 ? 117.170 39.896 22.770 1.00 84.70 ? 59 ALA D N 1 ATOM 3631 C CA . ALA D 1 59 ? 116.690 38.796 21.943 1.00 84.42 ? 59 ALA D CA 1 ATOM 3632 C C . ALA D 1 59 ? 117.855 37.877 21.574 1.00 83.20 ? 59 ALA D C 1 ATOM 3633 O O . ALA D 1 59 ? 117.761 36.655 21.713 1.00 84.95 ? 59 ALA D O 1 ATOM 3634 C CB . ALA D 1 59 ? 116.030 39.346 20.679 1.00 84.90 ? 59 ALA D CB 1 ATOM 3635 N N . LEU D 1 60 ? 118.950 38.468 21.102 1.00 79.70 ? 60 LEU D N 1 ATOM 3636 C CA . LEU D 1 60 ? 120.131 37.698 20.731 1.00 75.66 ? 60 LEU D CA 1 ATOM 3637 C C . LEU D 1 60 ? 120.546 36.836 21.916 1.00 73.63 ? 60 LEU D C 1 ATOM 3638 O O . LEU D 1 60 ? 121.248 35.831 21.759 1.00 70.22 ? 60 LEU D O 1 ATOM 3639 C CB . LEU D 1 60 ? 121.258 38.651 20.334 1.00 74.71 ? 60 LEU D CB 1 ATOM 3640 C CG . LEU D 1 60 ? 120.949 39.422 19.048 1.00 75.71 ? 60 LEU D CG 1 ATOM 3641 C CD1 . LEU D 1 60 ? 121.413 40.856 19.182 1.00 73.59 ? 60 LEU D CD1 1 ATOM 3642 C CD2 . LEU D 1 60 ? 121.594 38.718 17.855 1.00 74.43 ? 60 LEU D CD2 1 ATOM 3643 N N . ALA D 1 61 ? 120.085 37.245 23.099 1.00 72.86 ? 61 ALA D N 1 ATOM 3644 C CA . ALA D 1 61 ? 120.356 36.555 24.357 1.00 73.00 ? 61 ALA D CA 1 ATOM 3645 C C . ALA D 1 61 ? 119.569 35.259 24.406 1.00 73.94 ? 61 ALA D C 1 ATOM 3646 O O . ALA D 1 61 ? 120.121 34.204 24.729 1.00 75.27 ? 61 ALA D O 1 ATOM 3647 C CB . ALA D 1 61 ? 119.962 37.434 25.530 1.00 70.58 ? 61 ALA D CB 1 ATOM 3648 N N . ASN D 1 62 ? 118.274 35.350 24.103 1.00 74.09 ? 62 ASN D N 1 ATOM 3649 C CA . ASN D 1 62 ? 117.412 34.174 24.083 1.00 71.96 ? 62 ASN D CA 1 ATOM 3650 C C . ASN D 1 62 ? 117.875 33.207 22.999 1.00 70.98 ? 62 ASN D C 1 ATOM 3651 O O . ASN D 1 62 ? 118.137 32.040 23.288 1.00 72.79 ? 62 ASN D O 1 ATOM 3652 C CB . ASN D 1 62 ? 115.953 34.563 23.831 1.00 70.55 ? 62 ASN D CB 1 ATOM 3653 C CG . ASN D 1 62 ? 115.200 34.862 25.113 1.00 72.36 ? 62 ASN D CG 1 ATOM 3654 O OD1 . ASN D 1 62 ? 115.689 34.589 26.209 1.00 71.70 ? 62 ASN D OD1 1 ATOM 3655 N ND2 . ASN D 1 62 ? 113.993 35.411 24.981 1.00 72.71 ? 62 ASN D ND2 1 ATOM 3656 N N . ILE D 1 63 ? 117.989 33.691 21.762 1.00 67.87 ? 63 ILE D N 1 ATOM 3657 C CA . ILE D 1 63 ? 118.431 32.852 20.650 1.00 67.46 ? 63 ILE D CA 1 ATOM 3658 C C . ILE D 1 63 ? 119.622 31.970 21.019 1.00 69.33 ? 63 ILE D C 1 ATOM 3659 O O . ILE D 1 63 ? 119.727 30.835 20.545 1.00 70.95 ? 63 ILE D O 1 ATOM 3660 C CB . ILE D 1 63 ? 118.829 33.691 19.411 1.00 66.75 ? 63 ILE D CB 1 ATOM 3661 C CG1 . ILE D 1 63 ? 117.591 34.371 18.820 1.00 67.02 ? 63 ILE D CG1 1 ATOM 3662 C CG2 . ILE D 1 63 ? 119.484 32.793 18.355 1.00 62.90 ? 63 ILE D CG2 1 ATOM 3663 C CD1 . ILE D 1 63 ? 116.532 33.402 18.320 1.00 66.23 ? 63 ILE D CD1 1 ATOM 3664 N N . ALA D 1 64 ? 120.515 32.491 21.861 1.00 70.10 ? 64 ALA D N 1 ATOM 3665 C CA . ALA D 1 64 ? 121.703 31.751 22.297 1.00 69.24 ? 64 ALA D CA 1 ATOM 3666 C C . ALA D 1 64 ? 121.386 30.672 23.337 1.00 68.02 ? 64 ALA D C 1 ATOM 3667 O O . ALA D 1 64 ? 121.984 29.590 23.315 1.00 69.40 ? 64 ALA D O 1 ATOM 3668 C CB . ALA D 1 64 ? 122.737 32.715 22.851 1.00 70.43 ? 64 ALA D CB 1 ATOM 3669 N N . VAL D 1 65 ? 120.461 30.970 24.249 1.00 64.60 ? 65 VAL D N 1 ATOM 3670 C CA . VAL D 1 65 ? 120.064 30.006 25.272 1.00 62.89 ? 65 VAL D CA 1 ATOM 3671 C C . VAL D 1 65 ? 119.195 28.937 24.631 1.00 63.68 ? 65 VAL D C 1 ATOM 3672 O O . VAL D 1 65 ? 118.981 27.865 25.201 1.00 62.39 ? 65 VAL D O 1 ATOM 3673 C CB . VAL D 1 65 ? 119.261 30.662 26.391 1.00 60.21 ? 65 VAL D CB 1 ATOM 3674 C CG1 . VAL D 1 65 ? 118.948 29.637 27.468 1.00 57.88 ? 65 VAL D CG1 1 ATOM 3675 C CG2 . VAL D 1 65 ? 120.045 31.813 26.970 1.00 62.93 ? 65 VAL D CG2 1 ATOM 3676 N N . ASP D 1 66 ? 118.685 29.249 23.444 1.00 65.09 ? 66 ASP D N 1 ATOM 3677 C CA . ASP D 1 66 ? 117.864 28.312 22.699 1.00 67.32 ? 66 ASP D CA 1 ATOM 3678 C C . ASP D 1 66 ? 118.796 27.308 22.029 1.00 68.37 ? 66 ASP D C 1 ATOM 3679 O O . ASP D 1 66 ? 118.596 26.104 22.155 1.00 71.55 ? 66 ASP D O 1 ATOM 3680 C CB . ASP D 1 66 ? 117.009 29.031 21.645 1.00 68.19 ? 66 ASP D CB 1 ATOM 3681 C CG . ASP D 1 66 ? 115.884 29.868 22.264 1.00 68.54 ? 66 ASP D CG 1 ATOM 3682 O OD1 . ASP D 1 66 ? 115.268 29.416 23.260 1.00 63.02 ? 66 ASP D OD1 1 ATOM 3683 O OD2 . ASP D 1 66 ? 115.607 30.972 21.737 1.00 69.26 ? 66 ASP D OD2 1 ATOM 3684 N N . LYS D 1 67 ? 119.817 27.791 21.325 1.00 68.30 ? 67 LYS D N 1 ATOM 3685 C CA . LYS D 1 67 ? 120.765 26.886 20.681 1.00 69.32 ? 67 LYS D CA 1 ATOM 3686 C C . LYS D 1 67 ? 121.286 25.907 21.724 1.00 67.68 ? 67 LYS D C 1 ATOM 3687 O O . LYS D 1 67 ? 121.608 24.768 21.415 1.00 66.97 ? 67 LYS D O 1 ATOM 3688 C CB . LYS D 1 67 ? 121.955 27.644 20.099 1.00 73.38 ? 67 LYS D CB 1 ATOM 3689 C CG . LYS D 1 67 ? 123.017 26.710 19.521 1.00 78.98 ? 67 LYS D CG 1 ATOM 3690 C CD . LYS D 1 67 ? 124.440 27.208 19.774 1.00 84.89 ? 67 LYS D CD 1 ATOM 3691 C CE . LYS D 1 67 ? 124.757 28.478 18.993 1.00 87.94 ? 67 LYS D CE 1 ATOM 3692 N NZ . LYS D 1 67 ? 126.156 28.957 19.228 1.00 88.85 ? 67 LYS D NZ 1 ATOM 3693 N N . ALA D 1 68 ? 121.380 26.367 22.962 1.00 67.34 ? 68 ALA D N 1 ATOM 3694 C CA . ALA D 1 68 ? 121.848 25.520 24.043 1.00 72.07 ? 68 ALA D CA 1 ATOM 3695 C C . ALA D 1 68 ? 120.803 24.445 24.329 1.00 75.36 ? 68 ALA D C 1 ATOM 3696 O O . ALA D 1 68 ? 121.028 23.256 24.075 1.00 75.59 ? 68 ALA D O 1 ATOM 3697 C CB . ALA D 1 68 ? 122.084 26.360 25.287 1.00 73.71 ? 68 ALA D CB 1 ATOM 3698 N N . ASN D 1 69 ? 119.662 24.879 24.862 1.00 77.53 ? 69 ASN D N 1 ATOM 3699 C CA . ASN D 1 69 ? 118.559 23.986 25.193 1.00 78.71 ? 69 ASN D CA 1 ATOM 3700 C C . ASN D 1 69 ? 118.270 23.006 24.047 1.00 78.15 ? 69 ASN D C 1 ATOM 3701 O O . ASN D 1 69 ? 117.810 21.893 24.280 1.00 77.64 ? 69 ASN D O 1 ATOM 3702 C CB . ASN D 1 69 ? 117.307 24.812 25.505 1.00 82.41 ? 69 ASN D CB 1 ATOM 3703 C CG . ASN D 1 69 ? 116.171 23.969 26.052 1.00 87.44 ? 69 ASN D CG 1 ATOM 3704 O OD1 . ASN D 1 69 ? 116.232 23.480 27.185 1.00 88.35 ? 69 ASN D OD1 1 ATOM 3705 N ND2 . ASN D 1 69 ? 115.125 23.789 25.245 1.00 89.99 ? 69 ASN D ND2 1 ATOM 3706 N N . LEU D 1 70 ? 118.543 23.425 22.815 1.00 77.43 ? 70 LEU D N 1 ATOM 3707 C CA . LEU D 1 70 ? 118.324 22.579 21.646 1.00 77.99 ? 70 LEU D CA 1 ATOM 3708 C C . LEU D 1 70 ? 119.241 21.363 21.648 1.00 80.58 ? 70 LEU D C 1 ATOM 3709 O O . LEU D 1 70 ? 118.787 20.236 21.460 1.00 82.84 ? 70 LEU D O 1 ATOM 3710 C CB . LEU D 1 70 ? 118.562 23.376 20.365 1.00 77.30 ? 70 LEU D CB 1 ATOM 3711 C CG . LEU D 1 70 ? 118.706 22.589 19.059 1.00 77.63 ? 70 LEU D CG 1 ATOM 3712 C CD1 . LEU D 1 70 ? 117.437 21.805 18.743 1.00 75.13 ? 70 LEU D CD1 1 ATOM 3713 C CD2 . LEU D 1 70 ? 119.015 23.574 17.945 1.00 81.04 ? 70 LEU D CD2 1 ATOM 3714 N N . GLU D 1 71 ? 120.534 21.593 21.851 1.00 81.80 ? 71 GLU D N 1 ATOM 3715 C CA . GLU D 1 71 ? 121.501 20.503 21.864 1.00 81.51 ? 71 GLU D CA 1 ATOM 3716 C C . GLU D 1 71 ? 121.146 19.525 22.967 1.00 79.13 ? 71 GLU D C 1 ATOM 3717 O O . GLU D 1 71 ? 121.246 18.315 22.787 1.00 77.52 ? 71 GLU D O 1 ATOM 3718 C CB . GLU D 1 71 ? 122.913 21.054 22.063 1.00 86.07 ? 71 GLU D CB 1 ATOM 3719 C CG . GLU D 1 71 ? 123.182 22.281 21.200 1.00 95.23 ? 71 GLU D CG 1 ATOM 3720 C CD . GLU D 1 71 ? 124.654 22.534 20.950 1.00 100.44 ? 71 GLU D CD 1 ATOM 3721 O OE1 . GLU D 1 71 ? 125.453 22.365 21.898 1.00 104.52 ? 71 GLU D OE1 1 ATOM 3722 O OE2 . GLU D 1 71 ? 125.008 22.915 19.807 1.00 101.05 ? 71 GLU D OE2 1 ATOM 3723 N N . ILE D 1 72 ? 120.716 20.051 24.108 1.00 78.10 ? 72 ILE D N 1 ATOM 3724 C CA . ILE D 1 72 ? 120.328 19.197 25.220 1.00 78.27 ? 72 ILE D CA 1 ATOM 3725 C C . ILE D 1 72 ? 119.119 18.361 24.820 1.00 79.76 ? 72 ILE D C 1 ATOM 3726 O O . ILE D 1 72 ? 119.042 17.175 25.134 1.00 79.92 ? 72 ILE D O 1 ATOM 3727 C CB . ILE D 1 72 ? 119.966 20.024 26.471 1.00 76.25 ? 72 ILE D CB 1 ATOM 3728 C CG1 . ILE D 1 72 ? 121.182 20.834 26.920 1.00 76.17 ? 72 ILE D CG1 1 ATOM 3729 C CG2 . ILE D 1 72 ? 119.484 19.101 27.589 1.00 74.58 ? 72 ILE D CG2 1 ATOM 3730 C CD1 . ILE D 1 72 ? 120.996 21.555 28.236 1.00 76.34 ? 72 ILE D CD1 1 ATOM 3731 N N . MET D 1 73 ? 118.183 18.987 24.112 1.00 82.27 ? 73 MET D N 1 ATOM 3732 C CA . MET D 1 73 ? 116.961 18.320 23.669 1.00 83.92 ? 73 MET D CA 1 ATOM 3733 C C . MET D 1 73 ? 117.196 17.412 22.464 1.00 84.79 ? 73 MET D C 1 ATOM 3734 O O . MET D 1 73 ? 116.455 16.449 22.255 1.00 84.41 ? 73 MET D O 1 ATOM 3735 C CB . MET D 1 73 ? 115.891 19.354 23.303 1.00 84.59 ? 73 MET D CB 1 ATOM 3736 C CG . MET D 1 73 ? 114.477 18.842 23.465 1.00 84.25 ? 73 MET D CG 1 ATOM 3737 S SD . MET D 1 73 ? 114.123 18.570 25.215 1.00 82.24 ? 73 MET D SD 1 ATOM 3738 C CE . MET D 1 73 ? 113.380 20.163 25.611 1.00 86.62 ? 73 MET D CE 1 ATOM 3739 N N . THR D 1 74 ? 118.215 17.727 21.667 1.00 84.79 ? 74 THR D N 1 ATOM 3740 C CA . THR D 1 74 ? 118.520 16.932 20.486 1.00 84.10 ? 74 THR D CA 1 ATOM 3741 C C . THR D 1 74 ? 119.068 15.571 20.880 1.00 84.36 ? 74 THR D C 1 ATOM 3742 O O . THR D 1 74 ? 118.799 14.573 20.215 1.00 84.39 ? 74 THR D O 1 ATOM 3743 C CB . THR D 1 74 ? 119.549 17.630 19.571 1.00 83.36 ? 74 THR D CB 1 ATOM 3744 O OG1 . THR D 1 74 ? 118.999 18.855 19.070 1.00 84.30 ? 74 THR D OG1 1 ATOM 3745 C CG2 . THR D 1 74 ? 119.900 16.735 18.396 1.00 80.68 ? 74 THR D CG2 1 ATOM 3746 N N . LYS D 1 75 ? 119.827 15.526 21.969 1.00 85.03 ? 75 LYS D N 1 ATOM 3747 C CA . LYS D 1 75 ? 120.401 14.265 22.410 1.00 87.06 ? 75 LYS D CA 1 ATOM 3748 C C . LYS D 1 75 ? 119.414 13.449 23.231 1.00 88.79 ? 75 LYS D C 1 ATOM 3749 O O . LYS D 1 75 ? 119.288 12.237 23.043 1.00 88.58 ? 75 LYS D O 1 ATOM 3750 C CB . LYS D 1 75 ? 121.678 14.512 23.219 1.00 86.60 ? 75 LYS D CB 1 ATOM 3751 C CG . LYS D 1 75 ? 122.562 13.273 23.331 1.00 87.74 ? 75 LYS D CG 1 ATOM 3752 C CD . LYS D 1 75 ? 123.918 13.567 23.956 1.00 86.84 ? 75 LYS D CD 1 ATOM 3753 C CE . LYS D 1 75 ? 124.736 12.289 24.087 1.00 84.83 ? 75 LYS D CE 1 ATOM 3754 N NZ . LYS D 1 75 ? 124.073 11.281 24.972 1.00 83.71 ? 75 LYS D NZ 1 ATOM 3755 N N . ARG D 1 76 ? 118.702 14.120 24.130 1.00 91.60 ? 76 ARG D N 1 ATOM 3756 C CA . ARG D 1 76 ? 117.726 13.462 24.994 1.00 93.24 ? 76 ARG D CA 1 ATOM 3757 C C . ARG D 1 76 ? 116.652 12.745 24.183 1.00 93.60 ? 76 ARG D C 1 ATOM 3758 O O . ARG D 1 76 ? 115.657 12.283 24.734 1.00 93.24 ? 76 ARG D O 1 ATOM 3759 C CB . ARG D 1 76 ? 117.070 14.493 25.915 1.00 93.99 ? 76 ARG D CB 1 ATOM 3760 C CG . ARG D 1 76 ? 116.424 13.907 27.156 1.00 96.72 ? 76 ARG D CG 1 ATOM 3761 C CD . ARG D 1 76 ? 115.608 14.963 27.880 1.00 101.67 ? 76 ARG D CD 1 ATOM 3762 N NE . ARG D 1 76 ? 116.416 16.102 28.308 1.00 105.09 ? 76 ARG D NE 1 ATOM 3763 C CZ . ARG D 1 76 ? 115.913 17.282 28.655 1.00 106.86 ? 76 ARG D CZ 1 ATOM 3764 N NH1 . ARG D 1 76 ? 114.602 17.479 28.621 1.00 107.55 ? 76 ARG D NH1 1 ATOM 3765 N NH2 . ARG D 1 76 ? 116.717 18.266 29.037 1.00 108.50 ? 76 ARG D NH2 1 ATOM 3766 N N . SER D 1 77 ? 116.860 12.648 22.875 1.00 95.78 ? 77 SER D N 1 ATOM 3767 C CA . SER D 1 77 ? 115.905 11.996 21.989 1.00 99.09 ? 77 SER D CA 1 ATOM 3768 C C . SER D 1 77 ? 116.609 11.113 20.968 1.00 101.00 ? 77 SER D C 1 ATOM 3769 O O . SER D 1 77 ? 116.089 10.878 19.876 1.00 100.14 ? 77 SER D O 1 ATOM 3770 C CB . SER D 1 77 ? 115.082 13.050 21.257 1.00 99.71 ? 77 SER D CB 1 ATOM 3771 O OG . SER D 1 77 ? 115.933 13.932 20.545 1.00 100.26 ? 77 SER D OG 1 ATOM 3772 N N . ASN D 1 78 ? 117.791 10.626 21.332 1.00 103.66 ? 78 ASN D N 1 ATOM 3773 C CA . ASN D 1 78 ? 118.586 9.772 20.454 1.00 106.40 ? 78 ASN D CA 1 ATOM 3774 C C . ASN D 1 78 ? 118.811 10.415 19.081 1.00 102.05 ? 78 ASN D C 1 ATOM 3775 O O . ASN D 1 78 ? 118.784 9.739 18.052 1.00 101.33 ? 78 ASN D O 1 ATOM 3776 C CB . ASN D 1 78 ? 117.922 8.395 20.290 1.00 116.47 ? 78 ASN D CB 1 ATOM 3777 C CG . ASN D 1 78 ? 117.854 7.612 21.600 1.00 128.04 ? 78 ASN D CG 1 ATOM 3778 O OD1 . ASN D 1 78 ? 117.260 8.079 22.576 1.00 127.92 ? 78 ASN D OD1 1 ATOM 3779 N ND2 . ASN D 1 78 ? 118.457 6.421 21.622 1.00 140.62 ? 78 ASN D ND2 1 ATOM 3780 N N . TYR D 1 79 ? 119.029 11.728 19.080 1.00 96.85 ? 79 TYR D N 1 ATOM 3781 C CA . TYR D 1 79 ? 119.286 12.474 17.853 1.00 91.50 ? 79 TYR D CA 1 ATOM 3782 C C . TYR D 1 79 ? 118.358 12.128 16.695 1.00 86.47 ? 79 TYR D C 1 ATOM 3783 O O . TYR D 1 79 ? 118.804 11.569 15.702 1.00 84.54 ? 79 TYR D O 1 ATOM 3784 C CB . TYR D 1 79 ? 120.737 12.244 17.409 1.00 96.39 ? 79 TYR D CB 1 ATOM 3785 C CG . TYR D 1 79 ? 121.783 12.873 18.313 1.00 102.79 ? 79 TYR D CG 1 ATOM 3786 C CD1 . TYR D 1 79 ? 123.075 12.347 18.394 1.00 104.27 ? 79 TYR D CD1 1 ATOM 3787 C CD2 . TYR D 1 79 ? 121.488 14.004 19.076 1.00 105.56 ? 79 TYR D CD2 1 ATOM 3788 C CE1 . TYR D 1 79 ? 124.046 12.932 19.218 1.00 105.55 ? 79 TYR D CE1 1 ATOM 3789 C CE2 . TYR D 1 79 ? 122.452 14.597 19.900 1.00 106.51 ? 79 TYR D CE2 1 ATOM 3790 C CZ . TYR D 1 79 ? 123.725 14.056 19.968 1.00 105.81 ? 79 TYR D CZ 1 ATOM 3791 O OH . TYR D 1 79 ? 124.664 14.637 20.794 1.00 104.93 ? 79 TYR D OH 1 ATOM 3792 N N . THR D 1 80 ? 117.079 12.470 16.804 1.00 82.83 ? 80 THR D N 1 ATOM 3793 C CA . THR D 1 80 ? 116.128 12.177 15.732 1.00 77.91 ? 80 THR D CA 1 ATOM 3794 C C . THR D 1 80 ? 115.853 13.433 14.910 1.00 76.03 ? 80 THR D C 1 ATOM 3795 O O . THR D 1 80 ? 115.502 14.471 15.457 1.00 74.93 ? 80 THR D O 1 ATOM 3796 C CB . THR D 1 80 ? 114.802 11.675 16.287 1.00 76.61 ? 80 THR D CB 1 ATOM 3797 O OG1 . THR D 1 80 ? 114.181 12.730 17.022 1.00 76.96 ? 80 THR D OG1 1 ATOM 3798 C CG2 . THR D 1 80 ? 115.022 10.474 17.207 1.00 75.82 ? 80 THR D CG2 1 ATOM 3799 N N . PRO D 1 81 ? 115.996 13.339 13.578 1.00 76.21 ? 81 PRO D N 1 ATOM 3800 C CA . PRO D 1 81 ? 115.801 14.398 12.576 1.00 76.56 ? 81 PRO D CA 1 ATOM 3801 C C . PRO D 1 81 ? 114.367 14.873 12.343 1.00 76.32 ? 81 PRO D C 1 ATOM 3802 O O . PRO D 1 81 ? 113.453 14.058 12.213 1.00 79.11 ? 81 PRO D O 1 ATOM 3803 C CB . PRO D 1 81 ? 116.367 13.778 11.296 1.00 76.60 ? 81 PRO D CB 1 ATOM 3804 C CG . PRO D 1 81 ? 117.210 12.625 11.774 1.00 77.59 ? 81 PRO D CG 1 ATOM 3805 C CD . PRO D 1 81 ? 116.422 12.096 12.920 1.00 76.98 ? 81 PRO D CD 1 ATOM 3806 N N . ILE D 1 82 ? 114.169 16.186 12.271 1.00 73.37 ? 82 ILE D N 1 ATOM 3807 C CA . ILE D 1 82 ? 112.835 16.698 12.003 1.00 71.84 ? 82 ILE D CA 1 ATOM 3808 C C . ILE D 1 82 ? 112.504 16.120 10.638 1.00 70.39 ? 82 ILE D C 1 ATOM 3809 O O . ILE D 1 82 ? 113.397 15.919 9.814 1.00 69.85 ? 82 ILE D O 1 ATOM 3810 C CB . ILE D 1 82 ? 112.798 18.235 11.883 1.00 73.17 ? 82 ILE D CB 1 ATOM 3811 C CG1 . ILE D 1 82 ? 111.344 18.703 11.761 1.00 74.29 ? 82 ILE D CG1 1 ATOM 3812 C CG2 . ILE D 1 82 ? 113.581 18.685 10.648 1.00 72.51 ? 82 ILE D CG2 1 ATOM 3813 C CD1 . ILE D 1 82 ? 111.180 20.183 11.456 1.00 76.21 ? 82 ILE D CD1 1 ATOM 3814 N N . THR D 1 83 ? 111.233 15.847 10.390 1.00 67.78 ? 83 THR D N 1 ATOM 3815 C CA . THR D 1 83 ? 110.857 15.290 9.106 1.00 66.74 ? 83 THR D CA 1 ATOM 3816 C C . THR D 1 83 ? 110.526 16.392 8.114 1.00 63.63 ? 83 THR D C 1 ATOM 3817 O O . THR D 1 83 ? 109.633 17.201 8.345 1.00 63.64 ? 83 THR D O 1 ATOM 3818 C CB . THR D 1 83 ? 109.666 14.358 9.258 1.00 69.05 ? 83 THR D CB 1 ATOM 3819 O OG1 . THR D 1 83 ? 109.946 13.425 10.307 1.00 73.98 ? 83 THR D OG1 1 ATOM 3820 C CG2 . THR D 1 83 ? 109.417 13.592 7.964 1.00 69.56 ? 83 THR D CG2 1 ATOM 3821 N N . ASN D 1 84 ? 111.252 16.415 7.004 1.00 61.11 ? 84 ASN D N 1 ATOM 3822 C CA . ASN D 1 84 ? 111.042 17.428 5.983 1.00 60.96 ? 84 ASN D CA 1 ATOM 3823 C C . ASN D 1 84 ? 109.635 17.472 5.391 1.00 58.00 ? 84 ASN D C 1 ATOM 3824 O O . ASN D 1 84 ? 109.224 16.580 4.647 1.00 57.33 ? 84 ASN D O 1 ATOM 3825 C CB . ASN D 1 84 ? 112.056 17.258 4.847 1.00 66.29 ? 84 ASN D CB 1 ATOM 3826 C CG . ASN D 1 84 ? 113.492 17.418 5.316 1.00 72.96 ? 84 ASN D CG 1 ATOM 3827 O OD1 . ASN D 1 84 ? 113.787 18.217 6.212 1.00 75.61 ? 84 ASN D OD1 1 ATOM 3828 N ND2 . ASN D 1 84 ? 114.399 16.670 4.696 1.00 77.22 ? 84 ASN D ND2 1 ATOM 3829 N N . VAL D 1 85 ? 108.905 18.530 5.725 1.00 54.40 ? 85 VAL D N 1 ATOM 3830 C CA . VAL D 1 85 ? 107.560 18.729 5.214 1.00 49.31 ? 85 VAL D CA 1 ATOM 3831 C C . VAL D 1 85 ? 107.666 19.747 4.090 1.00 50.24 ? 85 VAL D C 1 ATOM 3832 O O . VAL D 1 85 ? 108.096 20.877 4.311 1.00 51.89 ? 85 VAL D O 1 ATOM 3833 C CB . VAL D 1 85 ? 106.632 19.289 6.288 1.00 46.28 ? 85 VAL D CB 1 ATOM 3834 C CG1 . VAL D 1 85 ? 105.250 19.476 5.713 1.00 45.17 ? 85 VAL D CG1 1 ATOM 3835 C CG2 . VAL D 1 85 ? 106.599 18.357 7.492 1.00 44.28 ? 85 VAL D CG2 1 ATOM 3836 N N . PRO D 1 86 ? 107.296 19.351 2.865 1.00 50.90 ? 86 PRO D N 1 ATOM 3837 C CA . PRO D 1 86 ? 107.326 20.181 1.653 1.00 52.18 ? 86 PRO D CA 1 ATOM 3838 C C . PRO D 1 86 ? 106.348 21.337 1.726 1.00 54.34 ? 86 PRO D C 1 ATOM 3839 O O . PRO D 1 86 ? 105.323 21.247 2.402 1.00 56.77 ? 86 PRO D O 1 ATOM 3840 C CB . PRO D 1 86 ? 106.950 19.206 0.551 1.00 51.65 ? 86 PRO D CB 1 ATOM 3841 C CG . PRO D 1 86 ? 107.439 17.899 1.086 1.00 57.07 ? 86 PRO D CG 1 ATOM 3842 C CD . PRO D 1 86 ? 107.005 17.953 2.523 1.00 53.71 ? 86 PRO D CD 1 ATOM 3843 N N . PRO D 1 87 ? 106.645 22.437 1.019 1.00 54.42 ? 87 PRO D N 1 ATOM 3844 C CA . PRO D 1 87 ? 105.765 23.600 1.033 1.00 51.22 ? 87 PRO D CA 1 ATOM 3845 C C . PRO D 1 87 ? 104.670 23.558 -0.005 1.00 49.60 ? 87 PRO D C 1 ATOM 3846 O O . PRO D 1 87 ? 104.716 22.807 -0.978 1.00 45.92 ? 87 PRO D O 1 ATOM 3847 C CB . PRO D 1 87 ? 106.710 24.769 0.760 1.00 50.22 ? 87 PRO D CB 1 ATOM 3848 C CG . PRO D 1 87 ? 108.066 24.217 1.016 1.00 55.91 ? 87 PRO D CG 1 ATOM 3849 C CD . PRO D 1 87 ? 107.959 22.818 0.493 1.00 57.11 ? 87 PRO D CD 1 ATOM 3850 N N . GLU D 1 88 ? 103.669 24.381 0.245 1.00 49.87 ? 88 GLU D N 1 ATOM 3851 C CA . GLU D 1 88 ? 102.568 24.545 -0.664 1.00 49.77 ? 88 GLU D CA 1 ATOM 3852 C C . GLU D 1 88 ? 102.930 25.921 -1.193 1.00 49.71 ? 88 GLU D C 1 ATOM 3853 O O . GLU D 1 88 ? 103.320 26.805 -0.428 1.00 47.14 ? 88 GLU D O 1 ATOM 3854 C CB . GLU D 1 88 ? 101.240 24.584 0.089 1.00 51.87 ? 88 GLU D CB 1 ATOM 3855 C CG . GLU D 1 88 ? 100.686 23.226 0.480 1.00 53.38 ? 88 GLU D CG 1 ATOM 3856 C CD . GLU D 1 88 ? 99.276 23.319 1.042 1.00 55.37 ? 88 GLU D CD 1 ATOM 3857 O OE1 . GLU D 1 88 ? 98.437 24.018 0.430 1.00 56.36 ? 88 GLU D OE1 1 ATOM 3858 O OE2 . GLU D 1 88 ? 98.999 22.688 2.085 1.00 54.40 ? 88 GLU D OE2 1 ATOM 3859 N N . VAL D 1 89 ? 102.838 26.102 -2.498 1.00 50.17 ? 89 VAL D N 1 ATOM 3860 C CA . VAL D 1 89 ? 103.195 27.379 -3.063 1.00 52.46 ? 89 VAL D CA 1 ATOM 3861 C C . VAL D 1 89 ? 102.161 27.888 -4.042 1.00 54.44 ? 89 VAL D C 1 ATOM 3862 O O . VAL D 1 89 ? 101.931 27.303 -5.097 1.00 54.14 ? 89 VAL D O 1 ATOM 3863 C CB . VAL D 1 89 ? 104.567 27.290 -3.750 1.00 53.66 ? 89 VAL D CB 1 ATOM 3864 C CG1 . VAL D 1 89 ? 104.823 28.535 -4.572 1.00 56.11 ? 89 VAL D CG1 1 ATOM 3865 C CG2 . VAL D 1 89 ? 105.654 27.128 -2.696 1.00 52.70 ? 89 VAL D CG2 1 ATOM 3866 N N . THR D 1 90 ? 101.526 28.987 -3.665 1.00 57.09 ? 90 THR D N 1 ATOM 3867 C CA . THR D 1 90 ? 100.518 29.623 -4.501 1.00 57.75 ? 90 THR D CA 1 ATOM 3868 C C . THR D 1 90 ? 101.062 30.999 -4.837 1.00 52.85 ? 90 THR D C 1 ATOM 3869 O O . THR D 1 90 ? 101.696 31.643 -3.994 1.00 48.78 ? 90 THR D O 1 ATOM 3870 C CB . THR D 1 90 ? 99.177 29.774 -3.744 1.00 62.92 ? 90 THR D CB 1 ATOM 3871 O OG1 . THR D 1 90 ? 99.441 30.044 -2.357 1.00 66.14 ? 90 THR D OG1 1 ATOM 3872 C CG2 . THR D 1 90 ? 98.336 28.501 -3.871 1.00 64.84 ? 90 THR D CG2 1 ATOM 3873 N N . VAL D 1 91 ? 100.843 31.446 -6.065 1.00 47.96 ? 91 VAL D N 1 ATOM 3874 C CA . VAL D 1 91 ? 101.338 32.754 -6.437 1.00 45.44 ? 91 VAL D CA 1 ATOM 3875 C C . VAL D 1 91 ? 100.203 33.608 -6.967 1.00 46.12 ? 91 VAL D C 1 ATOM 3876 O O . VAL D 1 91 ? 99.498 33.223 -7.897 1.00 46.11 ? 91 VAL D O 1 ATOM 3877 C CB . VAL D 1 91 ? 102.480 32.646 -7.468 1.00 44.14 ? 91 VAL D CB 1 ATOM 3878 C CG1 . VAL D 1 91 ? 101.966 32.827 -8.893 1.00 40.26 ? 91 VAL D CG1 1 ATOM 3879 C CG2 . VAL D 1 91 ? 103.544 33.662 -7.128 1.00 47.30 ? 91 VAL D CG2 1 ATOM 3880 N N . LEU D 1 92 ? 100.015 34.767 -6.347 1.00 47.26 ? 92 LEU D N 1 ATOM 3881 C CA . LEU D 1 92 ? 98.944 35.671 -6.743 1.00 47.54 ? 92 LEU D CA 1 ATOM 3882 C C . LEU D 1 92 ? 99.401 37.137 -6.839 1.00 50.66 ? 92 LEU D C 1 ATOM 3883 O O . LEU D 1 92 ? 100.533 37.484 -6.473 1.00 50.09 ? 92 LEU D O 1 ATOM 3884 C CB . LEU D 1 92 ? 97.765 35.552 -5.756 1.00 39.70 ? 92 LEU D CB 1 ATOM 3885 C CG . LEU D 1 92 ? 97.882 36.138 -4.336 1.00 33.61 ? 92 LEU D CG 1 ATOM 3886 C CD1 . LEU D 1 92 ? 96.511 36.091 -3.685 1.00 29.80 ? 92 LEU D CD1 1 ATOM 3887 C CD2 . LEU D 1 92 ? 98.915 35.388 -3.490 1.00 23.82 ? 92 LEU D CD2 1 ATOM 3888 N N . THR D 1 93 ? 98.501 37.982 -7.340 1.00 50.82 ? 93 THR D N 1 ATOM 3889 C CA . THR D 1 93 ? 98.741 39.403 -7.505 1.00 48.52 ? 93 THR D CA 1 ATOM 3890 C C . THR D 1 93 ? 98.192 40.134 -6.290 1.00 50.25 ? 93 THR D C 1 ATOM 3891 O O . THR D 1 93 ? 97.456 39.545 -5.503 1.00 51.44 ? 93 THR D O 1 ATOM 3892 C CB . THR D 1 93 ? 98.022 39.913 -8.717 1.00 49.08 ? 93 THR D CB 1 ATOM 3893 O OG1 . THR D 1 93 ? 98.280 41.310 -8.849 1.00 57.17 ? 93 THR D OG1 1 ATOM 3894 C CG2 . THR D 1 93 ? 96.519 39.687 -8.569 1.00 47.70 ? 93 THR D CG2 1 ATOM 3895 N N . ASN D 1 94 ? 98.529 41.415 -6.142 1.00 52.49 ? 94 ASN D N 1 ATOM 3896 C CA . ASN D 1 94 ? 98.066 42.199 -4.989 1.00 53.62 ? 94 ASN D CA 1 ATOM 3897 C C . ASN D 1 94 ? 96.764 42.947 -5.244 1.00 51.16 ? 94 ASN D C 1 ATOM 3898 O O . ASN D 1 94 ? 96.075 43.377 -4.310 1.00 47.19 ? 94 ASN D O 1 ATOM 3899 C CB . ASN D 1 94 ? 99.136 43.203 -4.559 1.00 57.68 ? 94 ASN D CB 1 ATOM 3900 C CG . ASN D 1 94 ? 98.744 43.967 -3.303 1.00 61.64 ? 94 ASN D CG 1 ATOM 3901 O OD1 . ASN D 1 94 ? 98.572 43.385 -2.228 1.00 63.38 ? 94 ASN D OD1 1 ATOM 3902 N ND2 . ASN D 1 94 ? 98.599 45.280 -3.436 1.00 64.11 ? 94 ASN D ND2 1 ATOM 3903 N N . SER D 1 95 ? 96.433 43.104 -6.514 1.00 49.89 ? 95 SER D N 1 ATOM 3904 C CA . SER D 1 95 ? 95.216 43.793 -6.885 1.00 51.20 ? 95 SER D CA 1 ATOM 3905 C C . SER D 1 95 ? 94.892 43.393 -8.296 1.00 50.29 ? 95 SER D C 1 ATOM 3906 O O . SER D 1 95 ? 95.740 42.849 -8.996 1.00 49.69 ? 95 SER D O 1 ATOM 3907 C CB . SER D 1 95 ? 95.434 45.295 -6.830 1.00 53.39 ? 95 SER D CB 1 ATOM 3908 O OG . SER D 1 95 ? 95.985 45.658 -5.580 1.00 61.96 ? 95 SER D OG 1 ATOM 3909 N N . PRO D 1 96 ? 93.651 43.632 -8.734 1.00 50.23 ? 96 PRO D N 1 ATOM 3910 C CA . PRO D 1 96 ? 93.317 43.262 -10.109 1.00 51.42 ? 96 PRO D CA 1 ATOM 3911 C C . PRO D 1 96 ? 94.437 43.733 -11.033 1.00 50.27 ? 96 PRO D C 1 ATOM 3912 O O . PRO D 1 96 ? 95.308 44.493 -10.618 1.00 50.52 ? 96 PRO D O 1 ATOM 3913 C CB . PRO D 1 96 ? 91.996 43.983 -10.331 1.00 49.99 ? 96 PRO D CB 1 ATOM 3914 C CG . PRO D 1 96 ? 91.334 43.789 -8.990 1.00 49.54 ? 96 PRO D CG 1 ATOM 3915 C CD . PRO D 1 96 ? 92.457 44.098 -8.008 1.00 47.46 ? 96 PRO D CD 1 ATOM 3916 N N . VAL D 1 97 ? 94.430 43.289 -12.278 1.00 51.61 ? 97 VAL D N 1 ATOM 3917 C CA . VAL D 1 97 ? 95.501 43.692 -13.167 1.00 55.46 ? 97 VAL D CA 1 ATOM 3918 C C . VAL D 1 97 ? 95.075 44.112 -14.557 1.00 58.56 ? 97 VAL D C 1 ATOM 3919 O O . VAL D 1 97 ? 94.226 43.482 -15.188 1.00 59.31 ? 97 VAL D O 1 ATOM 3920 C CB . VAL D 1 97 ? 96.530 42.562 -13.333 1.00 56.06 ? 97 VAL D CB 1 ATOM 3921 C CG1 . VAL D 1 97 ? 95.902 41.384 -14.080 1.00 53.19 ? 97 VAL D CG1 1 ATOM 3922 C CG2 . VAL D 1 97 ? 97.731 43.074 -14.088 1.00 57.96 ? 97 VAL D CG2 1 ATOM 3923 N N . GLU D 1 98 ? 95.673 45.195 -15.029 1.00 61.53 ? 98 GLU D N 1 ATOM 3924 C CA . GLU D 1 98 ? 95.407 45.658 -16.375 1.00 64.57 ? 98 GLU D CA 1 ATOM 3925 C C . GLU D 1 98 ? 96.725 46.136 -16.958 1.00 63.68 ? 98 GLU D C 1 ATOM 3926 O O . GLU D 1 98 ? 97.530 46.776 -16.281 1.00 63.10 ? 98 GLU D O 1 ATOM 3927 C CB . GLU D 1 98 ? 94.327 46.749 -16.404 1.00 68.10 ? 98 GLU D CB 1 ATOM 3928 C CG . GLU D 1 98 ? 94.463 47.859 -15.384 1.00 74.81 ? 98 GLU D CG 1 ATOM 3929 C CD . GLU D 1 98 ? 93.194 48.692 -15.292 1.00 77.65 ? 98 GLU D CD 1 ATOM 3930 O OE1 . GLU D 1 98 ? 92.778 49.255 -16.326 1.00 79.21 ? 98 GLU D OE1 1 ATOM 3931 O OE2 . GLU D 1 98 ? 92.611 48.776 -14.188 1.00 79.09 ? 98 GLU D OE2 1 ATOM 3932 N N . LEU D 1 99 ? 96.944 45.761 -18.210 1.00 61.96 ? 99 LEU D N 1 ATOM 3933 C CA . LEU D 1 99 ? 98.147 46.089 -18.949 1.00 59.92 ? 99 LEU D CA 1 ATOM 3934 C C . LEU D 1 99 ? 98.748 47.442 -18.594 1.00 61.80 ? 99 LEU D C 1 ATOM 3935 O O . LEU D 1 99 ? 98.039 48.447 -18.523 1.00 64.04 ? 99 LEU D O 1 ATOM 3936 C CB . LEU D 1 99 ? 97.825 46.015 -20.438 1.00 54.35 ? 99 LEU D CB 1 ATOM 3937 C CG . LEU D 1 99 ? 97.085 44.705 -20.722 1.00 50.56 ? 99 LEU D CG 1 ATOM 3938 C CD1 . LEU D 1 99 ? 96.684 44.614 -22.178 1.00 50.38 ? 99 LEU D CD1 1 ATOM 3939 C CD2 . LEU D 1 99 ? 97.980 43.542 -20.323 1.00 46.92 ? 99 LEU D CD2 1 ATOM 3940 N N . ARG D 1 100 ? 100.060 47.452 -18.360 1.00 62.69 ? 100 ARG D N 1 ATOM 3941 C CA . ARG D 1 100 ? 100.804 48.669 -18.033 1.00 63.12 ? 100 ARG D CA 1 ATOM 3942 C C . ARG D 1 100 ? 100.550 49.192 -16.627 1.00 62.93 ? 100 ARG D C 1 ATOM 3943 O O . ARG D 1 100 ? 101.202 50.128 -16.185 1.00 61.28 ? 100 ARG D O 1 ATOM 3944 C CB . ARG D 1 100 ? 100.472 49.768 -19.038 1.00 64.71 ? 100 ARG D CB 1 ATOM 3945 C CG . ARG D 1 100 ? 100.221 49.245 -20.439 1.00 69.27 ? 100 ARG D CG 1 ATOM 3946 C CD . ARG D 1 100 ? 101.430 48.530 -20.952 1.00 70.77 ? 100 ARG D CD 1 ATOM 3947 N NE . ARG D 1 100 ? 102.513 49.474 -21.157 1.00 73.77 ? 100 ARG D NE 1 ATOM 3948 C CZ . ARG D 1 100 ? 103.773 49.117 -21.344 1.00 77.21 ? 100 ARG D CZ 1 ATOM 3949 N NH1 . ARG D 1 100 ? 104.098 47.830 -21.343 1.00 77.03 ? 100 ARG D NH1 1 ATOM 3950 N NH2 . ARG D 1 100 ? 104.700 50.045 -21.541 1.00 79.64 ? 100 ARG D NH2 1 ATOM 3951 N N . GLU D 1 101 ? 99.599 48.595 -15.923 1.00 65.03 ? 101 GLU D N 1 ATOM 3952 C CA . GLU D 1 101 ? 99.297 49.041 -14.572 1.00 68.17 ? 101 GLU D CA 1 ATOM 3953 C C . GLU D 1 101 ? 100.216 48.392 -13.550 1.00 68.97 ? 101 GLU D C 1 ATOM 3954 O O . GLU D 1 101 ? 100.187 47.177 -13.345 1.00 72.08 ? 101 GLU D O 1 ATOM 3955 C CB . GLU D 1 101 ? 97.838 48.747 -14.225 1.00 70.30 ? 101 GLU D CB 1 ATOM 3956 C CG . GLU D 1 101 ? 97.013 49.999 -13.976 1.00 73.72 ? 101 GLU D CG 1 ATOM 3957 C CD . GLU D 1 101 ? 97.339 51.108 -14.960 1.00 75.20 ? 101 GLU D CD 1 ATOM 3958 O OE1 . GLU D 1 101 ? 98.302 51.864 -14.710 1.00 74.16 ? 101 GLU D OE1 1 ATOM 3959 O OE2 . GLU D 1 101 ? 96.642 51.213 -15.991 1.00 77.37 ? 101 GLU D OE2 1 ATOM 3960 N N . PRO D 1 102 ? 101.047 49.204 -12.891 1.00 67.79 ? 102 PRO D N 1 ATOM 3961 C CA . PRO D 1 102 ? 102.002 48.763 -11.872 1.00 67.12 ? 102 PRO D CA 1 ATOM 3962 C C . PRO D 1 102 ? 101.387 47.858 -10.810 1.00 65.57 ? 102 PRO D C 1 ATOM 3963 O O . PRO D 1 102 ? 100.612 48.307 -9.963 1.00 65.07 ? 102 PRO D O 1 ATOM 3964 C CB . PRO D 1 102 ? 102.506 50.076 -11.296 1.00 69.46 ? 102 PRO D CB 1 ATOM 3965 C CG . PRO D 1 102 ? 102.495 50.964 -12.500 1.00 71.13 ? 102 PRO D CG 1 ATOM 3966 C CD . PRO D 1 102 ? 101.158 50.653 -13.118 1.00 68.24 ? 102 PRO D CD 1 ATOM 3967 N N . ASN D 1 103 ? 101.754 46.582 -10.859 1.00 63.67 ? 103 ASN D N 1 ATOM 3968 C CA . ASN D 1 103 ? 101.246 45.594 -9.917 1.00 64.38 ? 103 ASN D CA 1 ATOM 3969 C C . ASN D 1 103 ? 102.351 45.001 -9.036 1.00 64.94 ? 103 ASN D C 1 ATOM 3970 O O . ASN D 1 103 ? 103.471 45.524 -8.990 1.00 67.02 ? 103 ASN D O 1 ATOM 3971 C CB . ASN D 1 103 ? 100.553 44.474 -10.691 1.00 63.75 ? 103 ASN D CB 1 ATOM 3972 C CG . ASN D 1 103 ? 99.076 44.403 -10.405 1.00 64.08 ? 103 ASN D CG 1 ATOM 3973 O OD1 . ASN D 1 103 ? 98.664 44.219 -9.255 1.00 63.51 ? 103 ASN D OD1 1 ATOM 3974 N ND2 . ASN D 1 103 ? 98.261 44.546 -11.450 1.00 63.84 ? 103 ASN D ND2 1 ATOM 3975 N N . VAL D 1 104 ? 102.025 43.912 -8.339 1.00 62.56 ? 104 VAL D N 1 ATOM 3976 C CA . VAL D 1 104 ? 102.978 43.219 -7.469 1.00 58.93 ? 104 VAL D CA 1 ATOM 3977 C C . VAL D 1 104 ? 102.606 41.748 -7.272 1.00 59.56 ? 104 VAL D C 1 ATOM 3978 O O . VAL D 1 104 ? 101.557 41.455 -6.697 1.00 62.69 ? 104 VAL D O 1 ATOM 3979 C CB . VAL D 1 104 ? 103.064 43.888 -6.075 1.00 53.85 ? 104 VAL D CB 1 ATOM 3980 C CG1 . VAL D 1 104 ? 103.804 42.982 -5.092 1.00 49.45 ? 104 VAL D CG1 1 ATOM 3981 C CG2 . VAL D 1 104 ? 103.789 45.213 -6.190 1.00 54.49 ? 104 VAL D CG2 1 ATOM 3982 N N . LEU D 1 105 ? 103.452 40.831 -7.753 1.00 56.48 ? 105 LEU D N 1 ATOM 3983 C CA . LEU D 1 105 ? 103.202 39.397 -7.587 1.00 51.38 ? 105 LEU D CA 1 ATOM 3984 C C . LEU D 1 105 ? 103.610 39.017 -6.168 1.00 52.13 ? 105 LEU D C 1 ATOM 3985 O O . LEU D 1 105 ? 104.631 39.491 -5.665 1.00 52.54 ? 105 LEU D O 1 ATOM 3986 C CB . LEU D 1 105 ? 104.022 38.559 -8.581 1.00 43.99 ? 105 LEU D CB 1 ATOM 3987 C CG . LEU D 1 105 ? 103.761 38.629 -10.090 1.00 40.53 ? 105 LEU D CG 1 ATOM 3988 C CD1 . LEU D 1 105 ? 104.749 37.726 -10.790 1.00 38.69 ? 105 LEU D CD1 1 ATOM 3989 C CD2 . LEU D 1 105 ? 102.345 38.205 -10.431 1.00 37.39 ? 105 LEU D CD2 1 ATOM 3990 N N . ILE D 1 106 ? 102.807 38.175 -5.523 1.00 53.49 ? 106 ILE D N 1 ATOM 3991 C CA . ILE D 1 106 ? 103.098 37.715 -4.165 1.00 55.24 ? 106 ILE D CA 1 ATOM 3992 C C . ILE D 1 106 ? 103.330 36.202 -4.181 1.00 55.78 ? 106 ILE D C 1 ATOM 3993 O O . ILE D 1 106 ? 102.383 35.439 -4.369 1.00 57.13 ? 106 ILE D O 1 ATOM 3994 C CB . ILE D 1 106 ? 101.921 37.987 -3.200 1.00 54.77 ? 106 ILE D CB 1 ATOM 3995 C CG1 . ILE D 1 106 ? 101.465 39.436 -3.324 1.00 57.51 ? 106 ILE D CG1 1 ATOM 3996 C CG2 . ILE D 1 106 ? 102.342 37.701 -1.762 1.00 50.29 ? 106 ILE D CG2 1 ATOM 3997 C CD1 . ILE D 1 106 ? 100.237 39.758 -2.485 1.00 61.08 ? 106 ILE D CD1 1 ATOM 3998 N N . CYS D 1 107 ? 104.576 35.763 -4.014 1.00 54.00 ? 107 CYS D N 1 ATOM 3999 C CA . CYS D 1 107 ? 104.830 34.333 -3.983 1.00 51.25 ? 107 CYS D CA 1 ATOM 4000 C C . CYS D 1 107 ? 104.585 33.931 -2.550 1.00 49.93 ? 107 CYS D C 1 ATOM 4001 O O . CYS D 1 107 ? 105.159 34.500 -1.621 1.00 45.22 ? 107 CYS D O 1 ATOM 4002 C CB . CYS D 1 107 ? 106.258 33.972 -4.372 1.00 53.08 ? 107 CYS D CB 1 ATOM 4003 S SG . CYS D 1 107 ? 106.438 32.164 -4.531 1.00 52.64 ? 107 CYS D SG 1 ATOM 4004 N N . PHE D 1 108 ? 103.720 32.940 -2.388 1.00 50.69 ? 108 PHE D N 1 ATOM 4005 C CA . PHE D 1 108 ? 103.322 32.467 -1.079 1.00 49.46 ? 108 PHE D CA 1 ATOM 4006 C C . PHE D 1 108 ? 103.747 31.025 -0.787 1.00 48.56 ? 108 PHE D C 1 ATOM 4007 O O . PHE D 1 108 ? 103.288 30.084 -1.447 1.00 48.99 ? 108 PHE D O 1 ATOM 4008 C CB . PHE D 1 108 ? 101.810 32.628 -0.978 1.00 49.02 ? 108 PHE D CB 1 ATOM 4009 C CG . PHE D 1 108 ? 101.262 32.348 0.369 1.00 50.56 ? 108 PHE D CG 1 ATOM 4010 C CD1 . PHE D 1 108 ? 102.015 32.604 1.505 1.00 49.98 ? 108 PHE D CD1 1 ATOM 4011 C CD2 . PHE D 1 108 ? 99.973 31.853 0.510 1.00 52.53 ? 108 PHE D CD2 1 ATOM 4012 C CE1 . PHE D 1 108 ? 101.492 32.372 2.764 1.00 51.97 ? 108 PHE D CE1 1 ATOM 4013 C CE2 . PHE D 1 108 ? 99.440 31.618 1.769 1.00 55.89 ? 108 PHE D CE2 1 ATOM 4014 C CZ . PHE D 1 108 ? 100.202 31.878 2.901 1.00 53.59 ? 108 PHE D CZ 1 ATOM 4015 N N . ILE D 1 109 ? 104.633 30.872 0.200 1.00 45.06 ? 109 ILE D N 1 ATOM 4016 C CA . ILE D 1 109 ? 105.142 29.568 0.613 1.00 42.98 ? 109 ILE D CA 1 ATOM 4017 C C . ILE D 1 109 ? 104.529 29.275 1.980 1.00 41.95 ? 109 ILE D C 1 ATOM 4018 O O . ILE D 1 109 ? 104.637 30.082 2.904 1.00 40.46 ? 109 ILE D O 1 ATOM 4019 C CB . ILE D 1 109 ? 106.695 29.558 0.717 1.00 43.81 ? 109 ILE D CB 1 ATOM 4020 C CG1 . ILE D 1 109 ? 107.339 29.897 -0.633 1.00 43.87 ? 109 ILE D CG1 1 ATOM 4021 C CG2 . ILE D 1 109 ? 107.174 28.178 1.093 1.00 44.96 ? 109 ILE D CG2 1 ATOM 4022 C CD1 . ILE D 1 109 ? 107.243 31.358 -1.040 1.00 46.15 ? 109 ILE D CD1 1 ATOM 4023 N N . ASP D 1 110 ? 103.896 28.114 2.111 1.00 41.15 ? 110 ASP D N 1 ATOM 4024 C CA . ASP D 1 110 ? 103.219 27.777 3.352 1.00 41.26 ? 110 ASP D CA 1 ATOM 4025 C C . ASP D 1 110 ? 103.195 26.288 3.687 1.00 42.11 ? 110 ASP D C 1 ATOM 4026 O O . ASP D 1 110 ? 103.378 25.438 2.816 1.00 40.67 ? 110 ASP D O 1 ATOM 4027 C CB . ASP D 1 110 ? 101.782 28.311 3.266 1.00 41.37 ? 110 ASP D CB 1 ATOM 4028 C CG . ASP D 1 110 ? 100.983 28.094 4.541 1.00 44.58 ? 110 ASP D CG 1 ATOM 4029 O OD1 . ASP D 1 110 ? 101.579 27.779 5.599 1.00 44.05 ? 110 ASP D OD1 1 ATOM 4030 O OD2 . ASP D 1 110 ? 99.746 28.261 4.487 1.00 45.22 ? 110 ASP D OD2 1 ATOM 4031 N N . LYS D 1 111 ? 102.967 25.995 4.967 1.00 42.26 ? 111 LYS D N 1 ATOM 4032 C CA . LYS D 1 111 ? 102.868 24.633 5.477 1.00 43.82 ? 111 LYS D CA 1 ATOM 4033 C C . LYS D 1 111 ? 104.095 23.771 5.268 1.00 45.99 ? 111 LYS D C 1 ATOM 4034 O O . LYS D 1 111 ? 103.975 22.619 4.860 1.00 48.26 ? 111 LYS D O 1 ATOM 4035 C CB . LYS D 1 111 ? 101.658 23.936 4.858 1.00 41.77 ? 111 LYS D CB 1 ATOM 4036 C CG . LYS D 1 111 ? 100.332 24.406 5.424 1.00 42.68 ? 111 LYS D CG 1 ATOM 4037 C CD . LYS D 1 111 ? 99.177 24.050 4.505 1.00 44.02 ? 111 LYS D CD 1 ATOM 4038 C CE . LYS D 1 111 ? 97.841 24.262 5.188 1.00 46.70 ? 111 LYS D CE 1 ATOM 4039 N NZ . LYS D 1 111 ? 97.708 25.635 5.745 1.00 50.81 ? 111 LYS D NZ 1 ATOM 4040 N N . PHE D 1 112 ? 105.269 24.319 5.563 1.00 47.56 ? 112 PHE D N 1 ATOM 4041 C CA . PHE D 1 112 ? 106.518 23.583 5.405 1.00 48.11 ? 112 PHE D CA 1 ATOM 4042 C C . PHE D 1 112 ? 107.364 23.651 6.673 1.00 47.76 ? 112 PHE D C 1 ATOM 4043 O O . PHE D 1 112 ? 107.006 24.320 7.637 1.00 48.36 ? 112 PHE D O 1 ATOM 4044 C CB . PHE D 1 112 ? 107.324 24.133 4.212 1.00 46.80 ? 112 PHE D CB 1 ATOM 4045 C CG . PHE D 1 112 ? 107.639 25.614 4.308 1.00 53.87 ? 112 PHE D CG 1 ATOM 4046 C CD1 . PHE D 1 112 ? 106.661 26.575 4.047 1.00 55.18 ? 112 PHE D CD1 1 ATOM 4047 C CD2 . PHE D 1 112 ? 108.912 26.051 4.674 1.00 54.00 ? 112 PHE D CD2 1 ATOM 4048 C CE1 . PHE D 1 112 ? 106.952 27.945 4.152 1.00 51.46 ? 112 PHE D CE1 1 ATOM 4049 C CE2 . PHE D 1 112 ? 109.205 27.419 4.779 1.00 48.36 ? 112 PHE D CE2 1 ATOM 4050 C CZ . PHE D 1 112 ? 108.227 28.359 4.519 1.00 47.33 ? 112 PHE D CZ 1 ATOM 4051 N N . THR D 1 113 ? 108.479 22.930 6.656 1.00 48.42 ? 113 THR D N 1 ATOM 4052 C CA . THR D 1 113 ? 109.442 22.884 7.754 1.00 47.69 ? 113 THR D CA 1 ATOM 4053 C C . THR D 1 113 ? 110.493 21.863 7.347 1.00 49.96 ? 113 THR D C 1 ATOM 4054 O O . THR D 1 113 ? 110.214 20.956 6.566 1.00 49.51 ? 113 THR D O 1 ATOM 4055 C CB . THR D 1 113 ? 108.816 22.442 9.094 1.00 44.87 ? 113 THR D CB 1 ATOM 4056 O OG1 . THR D 1 113 ? 109.798 22.550 10.130 1.00 43.35 ? 113 THR D OG1 1 ATOM 4057 C CG2 . THR D 1 113 ? 108.358 21.006 9.027 1.00 43.88 ? 113 THR D CG2 1 ATOM 4058 N N . PRO D 1 114 ? 111.726 22.013 7.840 1.00 51.86 ? 114 PRO D N 1 ATOM 4059 C CA . PRO D 1 114 ? 112.218 23.057 8.740 1.00 52.45 ? 114 PRO D CA 1 ATOM 4060 C C . PRO D 1 114 ? 112.305 24.396 8.013 1.00 52.91 ? 114 PRO D C 1 ATOM 4061 O O . PRO D 1 114 ? 112.243 24.450 6.781 1.00 51.06 ? 114 PRO D O 1 ATOM 4062 C CB . PRO D 1 114 ? 113.578 22.530 9.143 1.00 55.01 ? 114 PRO D CB 1 ATOM 4063 C CG . PRO D 1 114 ? 114.040 21.897 7.858 1.00 56.94 ? 114 PRO D CG 1 ATOM 4064 C CD . PRO D 1 114 ? 112.823 21.122 7.429 1.00 54.00 ? 114 PRO D CD 1 ATOM 4065 N N . PRO D 1 115 ? 112.486 25.492 8.767 1.00 53.29 ? 115 PRO D N 1 ATOM 4066 C CA . PRO D 1 115 ? 112.575 26.841 8.213 1.00 54.25 ? 115 PRO D CA 1 ATOM 4067 C C . PRO D 1 115 ? 113.799 27.094 7.340 1.00 57.40 ? 115 PRO D C 1 ATOM 4068 O O . PRO D 1 115 ? 114.703 27.830 7.729 1.00 61.94 ? 115 PRO D O 1 ATOM 4069 C CB . PRO D 1 115 ? 112.559 27.711 9.464 1.00 50.13 ? 115 PRO D CB 1 ATOM 4070 C CG . PRO D 1 115 ? 113.373 26.912 10.399 1.00 47.97 ? 115 PRO D CG 1 ATOM 4071 C CD . PRO D 1 115 ? 112.821 25.509 10.204 1.00 53.38 ? 115 PRO D CD 1 ATOM 4072 N N . VAL D 1 116 ? 113.830 26.491 6.159 1.00 57.00 ? 116 VAL D N 1 ATOM 4073 C CA . VAL D 1 116 ? 114.949 26.683 5.249 1.00 57.90 ? 116 VAL D CA 1 ATOM 4074 C C . VAL D 1 116 ? 114.430 26.499 3.850 1.00 59.82 ? 116 VAL D C 1 ATOM 4075 O O . VAL D 1 116 ? 113.991 25.412 3.491 1.00 59.63 ? 116 VAL D O 1 ATOM 4076 C CB . VAL D 1 116 ? 116.067 25.649 5.471 1.00 58.23 ? 116 VAL D CB 1 ATOM 4077 C CG1 . VAL D 1 116 ? 117.175 25.864 4.455 1.00 58.29 ? 116 VAL D CG1 1 ATOM 4078 C CG2 . VAL D 1 116 ? 116.620 25.759 6.876 1.00 56.43 ? 116 VAL D CG2 1 ATOM 4079 N N . VAL D 1 117 ? 114.494 27.551 3.048 1.00 63.08 ? 117 VAL D N 1 ATOM 4080 C CA . VAL D 1 117 ? 113.994 27.449 1.688 1.00 67.74 ? 117 VAL D CA 1 ATOM 4081 C C . VAL D 1 117 ? 114.681 28.458 0.763 1.00 68.67 ? 117 VAL D C 1 ATOM 4082 O O . VAL D 1 117 ? 115.428 29.316 1.230 1.00 69.15 ? 117 VAL D O 1 ATOM 4083 C CB . VAL D 1 117 ? 112.462 27.653 1.699 1.00 69.82 ? 117 VAL D CB 1 ATOM 4084 C CG1 . VAL D 1 117 ? 112.133 29.060 2.185 1.00 70.01 ? 117 VAL D CG1 1 ATOM 4085 C CG2 . VAL D 1 117 ? 111.874 27.359 0.329 1.00 70.97 ? 117 VAL D CG2 1 ATOM 4086 N N . ASN D 1 118 ? 114.439 28.347 -0.542 1.00 70.32 ? 118 ASN D N 1 ATOM 4087 C CA . ASN D 1 118 ? 115.051 29.256 -1.506 1.00 74.03 ? 118 ASN D CA 1 ATOM 4088 C C . ASN D 1 118 ? 114.135 29.739 -2.624 1.00 72.21 ? 118 ASN D C 1 ATOM 4089 O O . ASN D 1 118 ? 114.011 29.092 -3.667 1.00 71.85 ? 118 ASN D O 1 ATOM 4090 C CB . ASN D 1 118 ? 116.287 28.604 -2.113 1.00 83.38 ? 118 ASN D CB 1 ATOM 4091 C CG . ASN D 1 118 ? 117.439 28.563 -1.148 1.00 96.29 ? 118 ASN D CG 1 ATOM 4092 O OD1 . ASN D 1 118 ? 118.011 29.603 -0.817 1.00 96.81 ? 118 ASN D OD1 1 ATOM 4093 N ND2 . ASN D 1 118 ? 117.772 27.366 -0.676 1.00 110.88 ? 118 ASN D ND2 1 ATOM 4094 N N . VAL D 1 119 ? 113.514 30.895 -2.409 1.00 69.50 ? 119 VAL D N 1 ATOM 4095 C CA . VAL D 1 119 ? 112.614 31.476 -3.397 1.00 67.38 ? 119 VAL D CA 1 ATOM 4096 C C . VAL D 1 119 ? 113.425 32.214 -4.464 1.00 67.00 ? 119 VAL D C 1 ATOM 4097 O O . VAL D 1 119 ? 114.345 32.963 -4.145 1.00 66.92 ? 119 VAL D O 1 ATOM 4098 C CB . VAL D 1 119 ? 111.632 32.461 -2.734 1.00 64.93 ? 119 VAL D CB 1 ATOM 4099 C CG1 . VAL D 1 119 ? 110.561 32.867 -3.723 1.00 62.97 ? 119 VAL D CG1 1 ATOM 4100 C CG2 . VAL D 1 119 ? 111.007 31.825 -1.509 1.00 64.51 ? 119 VAL D CG2 1 ATOM 4101 N N . THR D 1 120 ? 113.074 32.004 -5.729 1.00 65.84 ? 120 THR D N 1 ATOM 4102 C CA . THR D 1 120 ? 113.782 32.630 -6.840 1.00 64.01 ? 120 THR D CA 1 ATOM 4103 C C . THR D 1 120 ? 112.798 33.074 -7.917 1.00 62.97 ? 120 THR D C 1 ATOM 4104 O O . THR D 1 120 ? 112.153 32.230 -8.546 1.00 61.32 ? 120 THR D O 1 ATOM 4105 C CB . THR D 1 120 ? 114.769 31.630 -7.480 1.00 65.52 ? 120 THR D CB 1 ATOM 4106 O OG1 . THR D 1 120 ? 115.619 31.076 -6.468 1.00 64.51 ? 120 THR D OG1 1 ATOM 4107 C CG2 . THR D 1 120 ? 115.617 32.313 -8.535 1.00 66.79 ? 120 THR D CG2 1 ATOM 4108 N N . TRP D 1 121 ? 112.676 34.384 -8.133 1.00 60.96 ? 121 TRP D N 1 ATOM 4109 C CA . TRP D 1 121 ? 111.756 34.882 -9.159 1.00 60.39 ? 121 TRP D CA 1 ATOM 4110 C C . TRP D 1 121 ? 112.395 34.697 -10.529 1.00 60.47 ? 121 TRP D C 1 ATOM 4111 O O . TRP D 1 121 ? 113.607 34.826 -10.673 1.00 58.46 ? 121 TRP D O 1 ATOM 4112 C CB . TRP D 1 121 ? 111.412 36.366 -8.944 1.00 57.62 ? 121 TRP D CB 1 ATOM 4113 C CG . TRP D 1 121 ? 110.528 36.651 -7.753 1.00 57.36 ? 121 TRP D CG 1 ATOM 4114 C CD1 . TRP D 1 121 ? 110.930 37.013 -6.491 1.00 60.57 ? 121 TRP D CD1 1 ATOM 4115 C CD2 . TRP D 1 121 ? 109.097 36.567 -7.704 1.00 56.40 ? 121 TRP D CD2 1 ATOM 4116 N NE1 . TRP D 1 121 ? 109.835 37.157 -5.662 1.00 58.58 ? 121 TRP D NE1 1 ATOM 4117 C CE2 . TRP D 1 121 ? 108.700 36.889 -6.381 1.00 57.94 ? 121 TRP D CE2 1 ATOM 4118 C CE3 . TRP D 1 121 ? 108.110 36.249 -8.647 1.00 55.55 ? 121 TRP D CE3 1 ATOM 4119 C CZ2 . TRP D 1 121 ? 107.359 36.901 -5.983 1.00 57.32 ? 121 TRP D CZ2 1 ATOM 4120 C CZ3 . TRP D 1 121 ? 106.770 36.262 -8.247 1.00 55.26 ? 121 TRP D CZ3 1 ATOM 4121 C CH2 . TRP D 1 121 ? 106.411 36.585 -6.928 1.00 56.47 ? 121 TRP D CH2 1 ATOM 4122 N N . LEU D 1 122 ? 111.583 34.389 -11.533 1.00 61.63 ? 122 LEU D N 1 ATOM 4123 C CA . LEU D 1 122 ? 112.107 34.180 -12.875 1.00 64.95 ? 122 LEU D CA 1 ATOM 4124 C C . LEU D 1 122 ? 111.185 34.774 -13.908 1.00 67.01 ? 122 LEU D C 1 ATOM 4125 O O . LEU D 1 122 ? 110.007 34.414 -13.960 1.00 67.12 ? 122 LEU D O 1 ATOM 4126 C CB . LEU D 1 122 ? 112.239 32.688 -13.187 1.00 66.25 ? 122 LEU D CB 1 ATOM 4127 C CG . LEU D 1 122 ? 112.949 31.748 -12.213 1.00 69.53 ? 122 LEU D CG 1 ATOM 4128 C CD1 . LEU D 1 122 ? 112.940 30.348 -12.801 1.00 69.76 ? 122 LEU D CD1 1 ATOM 4129 C CD2 . LEU D 1 122 ? 114.371 32.206 -11.963 1.00 71.39 ? 122 LEU D CD2 1 ATOM 4130 N N . ARG D 1 123 ? 111.717 35.679 -14.728 1.00 68.84 ? 123 ARG D N 1 ATOM 4131 C CA . ARG D 1 123 ? 110.929 36.283 -15.797 1.00 69.97 ? 123 ARG D CA 1 ATOM 4132 C C . ARG D 1 123 ? 111.365 35.701 -17.131 1.00 69.23 ? 123 ARG D C 1 ATOM 4133 O O . ARG D 1 123 ? 112.479 35.958 -17.583 1.00 68.65 ? 123 ARG D O 1 ATOM 4134 C CB . ARG D 1 123 ? 111.113 37.792 -15.872 1.00 72.24 ? 123 ARG D CB 1 ATOM 4135 C CG . ARG D 1 123 ? 110.258 38.387 -16.994 1.00 77.03 ? 123 ARG D CG 1 ATOM 4136 C CD . ARG D 1 123 ? 110.703 39.765 -17.387 1.00 79.14 ? 123 ARG D CD 1 ATOM 4137 N NE . ARG D 1 123 ? 111.004 40.554 -16.205 1.00 83.57 ? 123 ARG D NE 1 ATOM 4138 C CZ . ARG D 1 123 ? 111.268 41.851 -16.230 1.00 86.82 ? 123 ARG D CZ 1 ATOM 4139 N NH1 . ARG D 1 123 ? 111.263 42.503 -17.387 1.00 88.96 ? 123 ARG D NH1 1 ATOM 4140 N NH2 . ARG D 1 123 ? 111.548 42.488 -15.102 1.00 87.60 ? 123 ARG D NH2 1 ATOM 4141 N N . ASN D 1 124 ? 110.483 34.924 -17.756 1.00 68.90 ? 124 ASN D N 1 ATOM 4142 C CA . ASN D 1 124 ? 110.773 34.300 -19.042 1.00 68.20 ? 124 ASN D CA 1 ATOM 4143 C C . ASN D 1 124 ? 111.928 33.301 -18.909 1.00 68.33 ? 124 ASN D C 1 ATOM 4144 O O . ASN D 1 124 ? 112.098 32.402 -19.735 1.00 71.09 ? 124 ASN D O 1 ATOM 4145 C CB . ASN D 1 124 ? 111.120 35.381 -20.064 1.00 67.50 ? 124 ASN D CB 1 ATOM 4146 C CG . ASN D 1 124 ? 110.019 36.407 -20.216 1.00 65.48 ? 124 ASN D CG 1 ATOM 4147 O OD1 . ASN D 1 124 ? 108.949 36.106 -20.743 1.00 63.23 ? 124 ASN D OD1 1 ATOM 4148 N ND2 . ASN D 1 124 ? 110.272 37.629 -19.749 1.00 63.79 ? 124 ASN D ND2 1 ATOM 4149 N N . GLY D 1 125 ? 112.716 33.468 -17.855 1.00 66.70 ? 125 GLY D N 1 ATOM 4150 C CA . GLY D 1 125 ? 113.837 32.589 -17.605 1.00 63.81 ? 125 GLY D CA 1 ATOM 4151 C C . GLY D 1 125 ? 114.703 33.274 -16.579 1.00 63.98 ? 125 GLY D C 1 ATOM 4152 O O . GLY D 1 125 ? 114.954 32.759 -15.492 1.00 61.27 ? 125 GLY D O 1 ATOM 4153 N N . LYS D 1 126 ? 115.128 34.476 -16.934 1.00 66.94 ? 126 LYS D N 1 ATOM 4154 C CA . LYS D 1 126 ? 115.987 35.285 -16.088 1.00 70.95 ? 126 LYS D CA 1 ATOM 4155 C C . LYS D 1 126 ? 115.501 35.519 -14.662 1.00 68.56 ? 126 LYS D C 1 ATOM 4156 O O . LYS D 1 126 ? 114.321 35.778 -14.416 1.00 68.62 ? 126 LYS D O 1 ATOM 4157 C CB . LYS D 1 126 ? 116.246 36.643 -16.759 1.00 77.76 ? 126 LYS D CB 1 ATOM 4158 C CG . LYS D 1 126 ? 117.558 36.731 -17.552 1.00 85.23 ? 126 LYS D CG 1 ATOM 4159 C CD . LYS D 1 126 ? 117.670 35.651 -18.625 1.00 89.46 ? 126 LYS D CD 1 ATOM 4160 C CE . LYS D 1 126 ? 119.001 35.746 -19.362 1.00 92.07 ? 126 LYS D CE 1 ATOM 4161 N NZ . LYS D 1 126 ? 119.157 34.668 -20.379 1.00 94.04 ? 126 LYS D NZ 1 ATOM 4162 N N . PRO D 1 127 ? 116.423 35.408 -13.697 1.00 66.56 ? 127 PRO D N 1 ATOM 4163 C CA . PRO D 1 127 ? 116.114 35.618 -12.283 1.00 67.68 ? 127 PRO D CA 1 ATOM 4164 C C . PRO D 1 127 ? 116.015 37.130 -12.110 1.00 69.34 ? 127 PRO D C 1 ATOM 4165 O O . PRO D 1 127 ? 116.375 37.870 -13.019 1.00 72.47 ? 127 PRO D O 1 ATOM 4166 C CB . PRO D 1 127 ? 117.347 35.052 -11.574 1.00 65.95 ? 127 PRO D CB 1 ATOM 4167 C CG . PRO D 1 127 ? 117.911 34.068 -12.561 1.00 62.83 ? 127 PRO D CG 1 ATOM 4168 C CD . PRO D 1 127 ? 117.755 34.799 -13.853 1.00 63.53 ? 127 PRO D CD 1 ATOM 4169 N N . VAL D 1 128 ? 115.528 37.605 -10.972 1.00 70.36 ? 128 VAL D N 1 ATOM 4170 C CA . VAL D 1 128 ? 115.461 39.045 -10.772 1.00 72.01 ? 128 VAL D CA 1 ATOM 4171 C C . VAL D 1 128 ? 115.624 39.436 -9.314 1.00 75.84 ? 128 VAL D C 1 ATOM 4172 O O . VAL D 1 128 ? 114.928 38.925 -8.436 1.00 74.46 ? 128 VAL D O 1 ATOM 4173 C CB . VAL D 1 128 ? 114.142 39.647 -11.292 1.00 68.38 ? 128 VAL D CB 1 ATOM 4174 C CG1 . VAL D 1 128 ? 113.959 39.330 -12.766 1.00 67.28 ? 128 VAL D CG1 1 ATOM 4175 C CG2 . VAL D 1 128 ? 112.990 39.132 -10.477 1.00 68.73 ? 128 VAL D CG2 1 ATOM 4176 N N . THR D 1 129 ? 116.569 40.343 -9.076 1.00 81.55 ? 129 THR D N 1 ATOM 4177 C CA . THR D 1 129 ? 116.861 40.867 -7.742 1.00 85.30 ? 129 THR D CA 1 ATOM 4178 C C . THR D 1 129 ? 116.494 42.351 -7.781 1.00 87.55 ? 129 THR D C 1 ATOM 4179 O O . THR D 1 129 ? 116.693 43.092 -6.812 1.00 88.20 ? 129 THR D O 1 ATOM 4180 C CB . THR D 1 129 ? 118.365 40.738 -7.396 1.00 84.25 ? 129 THR D CB 1 ATOM 4181 O OG1 . THR D 1 129 ? 118.814 39.408 -7.683 1.00 84.37 ? 129 THR D OG1 1 ATOM 4182 C CG2 . THR D 1 129 ? 118.597 41.035 -5.919 1.00 82.78 ? 129 THR D CG2 1 ATOM 4183 N N . THR D 1 130 ? 115.953 42.763 -8.925 1.00 89.25 ? 130 THR D N 1 ATOM 4184 C CA . THR D 1 130 ? 115.546 44.143 -9.162 1.00 90.00 ? 130 THR D CA 1 ATOM 4185 C C . THR D 1 130 ? 114.386 44.542 -8.252 1.00 88.54 ? 130 THR D C 1 ATOM 4186 O O . THR D 1 130 ? 113.227 44.275 -8.563 1.00 89.15 ? 130 THR D O 1 ATOM 4187 C CB . THR D 1 130 ? 115.134 44.338 -10.649 1.00 91.53 ? 130 THR D CB 1 ATOM 4188 O OG1 . THR D 1 130 ? 113.953 43.573 -10.929 1.00 92.44 ? 130 THR D OG1 1 ATOM 4189 C CG2 . THR D 1 130 ? 116.257 43.865 -11.581 1.00 90.63 ? 130 THR D CG2 1 ATOM 4190 N N . GLY D 1 131 ? 114.707 45.179 -7.128 1.00 87.32 ? 131 GLY D N 1 ATOM 4191 C CA . GLY D 1 131 ? 113.676 45.597 -6.193 1.00 86.56 ? 131 GLY D CA 1 ATOM 4192 C C . GLY D 1 131 ? 112.669 44.494 -5.921 1.00 84.77 ? 131 GLY D C 1 ATOM 4193 O O . GLY D 1 131 ? 111.589 44.459 -6.512 1.00 84.67 ? 131 GLY D O 1 ATOM 4194 N N . VAL D 1 132 ? 113.018 43.594 -5.013 1.00 82.67 ? 132 VAL D N 1 ATOM 4195 C CA . VAL D 1 132 ? 112.150 42.476 -4.686 1.00 80.51 ? 132 VAL D CA 1 ATOM 4196 C C . VAL D 1 132 ? 112.454 41.997 -3.267 1.00 80.77 ? 132 VAL D C 1 ATOM 4197 O O . VAL D 1 132 ? 113.462 41.335 -3.035 1.00 81.20 ? 132 VAL D O 1 ATOM 4198 C CB . VAL D 1 132 ? 112.358 41.339 -5.730 1.00 77.90 ? 132 VAL D CB 1 ATOM 4199 C CG1 . VAL D 1 132 ? 113.829 41.158 -6.005 1.00 76.46 ? 132 VAL D CG1 1 ATOM 4200 C CG2 . VAL D 1 132 ? 111.767 40.042 -5.240 1.00 79.41 ? 132 VAL D CG2 1 ATOM 4201 N N . SER D 1 133 ? 111.578 42.342 -2.322 1.00 81.22 ? 133 SER D N 1 ATOM 4202 C CA . SER D 1 133 ? 111.763 41.968 -0.915 1.00 83.67 ? 133 SER D CA 1 ATOM 4203 C C . SER D 1 133 ? 111.068 40.677 -0.497 1.00 83.51 ? 133 SER D C 1 ATOM 4204 O O . SER D 1 133 ? 110.443 39.992 -1.310 1.00 83.67 ? 133 SER D O 1 ATOM 4205 C CB . SER D 1 133 ? 111.284 43.093 0.010 1.00 86.11 ? 133 SER D CB 1 ATOM 4206 O OG . SER D 1 133 ? 109.866 43.179 0.037 1.00 87.36 ? 133 SER D OG 1 ATOM 4207 N N . GLU D 1 134 ? 111.163 40.368 0.793 1.00 82.02 ? 134 GLU D N 1 ATOM 4208 C CA . GLU D 1 134 ? 110.563 39.154 1.322 1.00 82.59 ? 134 GLU D CA 1 ATOM 4209 C C . GLU D 1 134 ? 110.276 39.240 2.817 1.00 80.47 ? 134 GLU D C 1 ATOM 4210 O O . GLU D 1 134 ? 110.843 40.069 3.527 1.00 80.21 ? 134 GLU D O 1 ATOM 4211 C CB . GLU D 1 134 ? 111.502 37.981 1.076 1.00 87.44 ? 134 GLU D CB 1 ATOM 4212 C CG . GLU D 1 134 ? 112.744 38.017 1.961 1.00 94.62 ? 134 GLU D CG 1 ATOM 4213 C CD . GLU D 1 134 ? 113.790 36.990 1.569 1.00 98.32 ? 134 GLU D CD 1 ATOM 4214 O OE1 . GLU D 1 134 ? 114.414 37.163 0.496 1.00 100.02 ? 134 GLU D OE1 1 ATOM 4215 O OE2 . GLU D 1 134 ? 113.985 36.013 2.332 1.00 98.09 ? 134 GLU D OE2 1 ATOM 4216 N N . THR D 1 135 ? 109.391 38.367 3.286 1.00 78.28 ? 135 THR D N 1 ATOM 4217 C CA . THR D 1 135 ? 109.041 38.317 4.697 1.00 75.77 ? 135 THR D CA 1 ATOM 4218 C C . THR D 1 135 ? 110.027 37.363 5.324 1.00 75.06 ? 135 THR D C 1 ATOM 4219 O O . THR D 1 135 ? 110.774 36.689 4.617 1.00 75.27 ? 135 THR D O 1 ATOM 4220 C CB . THR D 1 135 ? 107.624 37.752 4.921 1.00 75.68 ? 135 THR D CB 1 ATOM 4221 O OG1 . THR D 1 135 ? 107.500 36.492 4.251 1.00 73.73 ? 135 THR D OG1 1 ATOM 4222 C CG2 . THR D 1 135 ? 106.570 38.714 4.396 1.00 75.11 ? 135 THR D CG2 1 ATOM 4223 N N . VAL D 1 136 ? 110.036 37.300 6.646 1.00 73.94 ? 136 VAL D N 1 ATOM 4224 C CA . VAL D 1 136 ? 110.942 36.394 7.331 1.00 73.33 ? 136 VAL D CA 1 ATOM 4225 C C . VAL D 1 136 ? 110.285 35.026 7.428 1.00 72.86 ? 136 VAL D C 1 ATOM 4226 O O . VAL D 1 136 ? 109.875 34.458 6.417 1.00 73.72 ? 136 VAL D O 1 ATOM 4227 C CB . VAL D 1 136 ? 111.266 36.912 8.731 1.00 73.56 ? 136 VAL D CB 1 ATOM 4228 C CG1 . VAL D 1 136 ? 112.176 38.124 8.628 1.00 75.19 ? 136 VAL D CG1 1 ATOM 4229 C CG2 . VAL D 1 136 ? 109.984 37.292 9.444 1.00 75.75 ? 136 VAL D CG2 1 ATOM 4230 N N . PHE D 1 137 ? 110.189 34.494 8.640 1.00 71.84 ? 137 PHE D N 1 ATOM 4231 C CA . PHE D 1 137 ? 109.557 33.198 8.852 1.00 69.25 ? 137 PHE D CA 1 ATOM 4232 C C . PHE D 1 137 ? 108.418 33.341 9.826 1.00 67.30 ? 137 PHE D C 1 ATOM 4233 O O . PHE D 1 137 ? 108.631 33.419 11.033 1.00 68.59 ? 137 PHE D O 1 ATOM 4234 C CB . PHE D 1 137 ? 110.565 32.186 9.391 1.00 69.27 ? 137 PHE D CB 1 ATOM 4235 C CG . PHE D 1 137 ? 111.285 31.438 8.321 1.00 70.72 ? 137 PHE D CG 1 ATOM 4236 C CD1 . PHE D 1 137 ? 112.555 30.935 8.545 1.00 70.92 ? 137 PHE D CD1 1 ATOM 4237 C CD2 . PHE D 1 137 ? 110.687 31.231 7.079 1.00 72.50 ? 137 PHE D CD2 1 ATOM 4238 C CE1 . PHE D 1 137 ? 113.226 30.237 7.549 1.00 73.58 ? 137 PHE D CE1 1 ATOM 4239 C CE2 . PHE D 1 137 ? 111.347 30.532 6.075 1.00 74.34 ? 137 PHE D CE2 1 ATOM 4240 C CZ . PHE D 1 137 ? 112.622 30.033 6.310 1.00 75.07 ? 137 PHE D CZ 1 ATOM 4241 N N . LEU D 1 138 ? 107.202 33.395 9.303 1.00 63.90 ? 138 LEU D N 1 ATOM 4242 C CA . LEU D 1 138 ? 106.053 33.524 10.171 1.00 61.45 ? 138 LEU D CA 1 ATOM 4243 C C . LEU D 1 138 ? 105.673 32.139 10.672 1.00 59.54 ? 138 LEU D C 1 ATOM 4244 O O . LEU D 1 138 ? 105.496 31.209 9.890 1.00 58.25 ? 138 LEU D O 1 ATOM 4245 C CB . LEU D 1 138 ? 104.886 34.179 9.433 1.00 62.22 ? 138 LEU D CB 1 ATOM 4246 C CG . LEU D 1 138 ? 105.062 35.638 9.008 1.00 60.30 ? 138 LEU D CG 1 ATOM 4247 C CD1 . LEU D 1 138 ? 106.003 35.734 7.813 1.00 59.01 ? 138 LEU D CD1 1 ATOM 4248 C CD2 . LEU D 1 138 ? 103.702 36.206 8.648 1.00 62.56 ? 138 LEU D CD2 1 ATOM 4249 N N . PRO D 1 139 ? 105.555 31.990 11.997 1.00 59.06 ? 139 PRO D N 1 ATOM 4250 C CA . PRO D 1 139 ? 105.205 30.749 12.687 1.00 60.57 ? 139 PRO D CA 1 ATOM 4251 C C . PRO D 1 139 ? 103.743 30.401 12.531 1.00 62.18 ? 139 PRO D C 1 ATOM 4252 O O . PRO D 1 139 ? 102.885 31.284 12.594 1.00 64.44 ? 139 PRO D O 1 ATOM 4253 C CB . PRO D 1 139 ? 105.541 31.067 14.130 1.00 62.05 ? 139 PRO D CB 1 ATOM 4254 C CG . PRO D 1 139 ? 105.126 32.498 14.225 1.00 60.48 ? 139 PRO D CG 1 ATOM 4255 C CD . PRO D 1 139 ? 105.707 33.092 12.964 1.00 59.29 ? 139 PRO D CD 1 ATOM 4256 N N . ARG D 1 140 ? 103.462 29.114 12.341 1.00 61.72 ? 140 ARG D N 1 ATOM 4257 C CA . ARG D 1 140 ? 102.089 28.657 12.191 1.00 59.65 ? 140 ARG D CA 1 ATOM 4258 C C . ARG D 1 140 ? 101.566 28.118 13.508 1.00 60.63 ? 140 ARG D C 1 ATOM 4259 O O . ARG D 1 140 ? 102.241 28.204 14.535 1.00 60.02 ? 140 ARG D O 1 ATOM 4260 C CB . ARG D 1 140 ? 101.995 27.594 11.100 1.00 54.33 ? 140 ARG D CB 1 ATOM 4261 C CG . ARG D 1 140 ? 102.095 28.178 9.710 1.00 52.79 ? 140 ARG D CG 1 ATOM 4262 C CD . ARG D 1 140 ? 102.259 27.099 8.675 1.00 52.74 ? 140 ARG D CD 1 ATOM 4263 N NE . ARG D 1 140 ? 101.176 26.125 8.726 1.00 53.56 ? 140 ARG D NE 1 ATOM 4264 C CZ . ARG D 1 140 ? 99.941 26.352 8.295 1.00 53.23 ? 140 ARG D CZ 1 ATOM 4265 N NH1 . ARG D 1 140 ? 99.628 27.532 7.776 1.00 54.35 ? 140 ARG D NH1 1 ATOM 4266 N NH2 . ARG D 1 140 ? 99.026 25.391 8.371 1.00 51.04 ? 140 ARG D NH2 1 ATOM 4267 N N . GLU D 1 141 ? 100.356 27.573 13.474 1.00 63.10 ? 141 GLU D N 1 ATOM 4268 C CA . GLU D 1 141 ? 99.730 27.032 14.672 1.00 65.76 ? 141 GLU D CA 1 ATOM 4269 C C . GLU D 1 141 ? 100.066 25.561 14.864 1.00 63.98 ? 141 GLU D C 1 ATOM 4270 O O . GLU D 1 141 ? 99.961 25.025 15.969 1.00 61.76 ? 141 GLU D O 1 ATOM 4271 C CB . GLU D 1 141 ? 98.221 27.210 14.582 1.00 70.25 ? 141 GLU D CB 1 ATOM 4272 C CG . GLU D 1 141 ? 97.608 27.705 15.862 1.00 78.36 ? 141 GLU D CG 1 ATOM 4273 C CD . GLU D 1 141 ? 96.300 28.419 15.620 1.00 84.93 ? 141 GLU D CD 1 ATOM 4274 O OE1 . GLU D 1 141 ? 96.281 29.347 14.775 1.00 85.29 ? 141 GLU D OE1 1 ATOM 4275 O OE2 . GLU D 1 141 ? 95.299 28.054 16.276 1.00 90.23 ? 141 GLU D OE2 1 ATOM 4276 N N . ASP D 1 142 ? 100.463 24.916 13.772 1.00 62.74 ? 142 ASP D N 1 ATOM 4277 C CA . ASP D 1 142 ? 100.831 23.509 13.803 1.00 60.73 ? 142 ASP D CA 1 ATOM 4278 C C . ASP D 1 142 ? 102.344 23.382 13.936 1.00 59.61 ? 142 ASP D C 1 ATOM 4279 O O . ASP D 1 142 ? 102.878 22.279 14.039 1.00 63.37 ? 142 ASP D O 1 ATOM 4280 C CB . ASP D 1 142 ? 100.334 22.784 12.535 1.00 59.13 ? 142 ASP D CB 1 ATOM 4281 C CG . ASP D 1 142 ? 100.780 23.458 11.246 1.00 55.43 ? 142 ASP D CG 1 ATOM 4282 O OD1 . ASP D 1 142 ? 101.991 23.717 11.100 1.00 57.01 ? 142 ASP D OD1 1 ATOM 4283 O OD2 . ASP D 1 142 ? 99.922 23.713 10.372 1.00 50.44 ? 142 ASP D OD2 1 ATOM 4284 N N . HIS D 1 143 ? 103.020 24.526 13.933 1.00 55.31 ? 143 HIS D N 1 ATOM 4285 C CA . HIS D 1 143 ? 104.467 24.592 14.061 1.00 50.38 ? 143 HIS D CA 1 ATOM 4286 C C . HIS D 1 143 ? 105.233 24.320 12.787 1.00 48.12 ? 143 HIS D C 1 ATOM 4287 O O . HIS D 1 143 ? 106.313 23.742 12.803 1.00 46.29 ? 143 HIS D O 1 ATOM 4288 C CB . HIS D 1 143 ? 104.927 23.674 15.177 1.00 46.38 ? 143 HIS D CB 1 ATOM 4289 C CG . HIS D 1 143 ? 104.135 23.857 16.423 1.00 47.98 ? 143 HIS D CG 1 ATOM 4290 N ND1 . HIS D 1 143 ? 103.613 25.080 16.782 1.00 50.72 ? 143 HIS D ND1 1 ATOM 4291 C CD2 . HIS D 1 143 ? 103.740 22.982 17.376 1.00 54.45 ? 143 HIS D CD2 1 ATOM 4292 C CE1 . HIS D 1 143 ? 102.928 24.950 17.904 1.00 58.42 ? 143 HIS D CE1 1 ATOM 4293 N NE2 . HIS D 1 143 ? 102.989 23.686 18.286 1.00 58.83 ? 143 HIS D NE2 1 ATOM 4294 N N . LEU D 1 144 ? 104.643 24.728 11.677 1.00 47.54 ? 144 LEU D N 1 ATOM 4295 C CA . LEU D 1 144 ? 105.291 24.619 10.387 1.00 50.84 ? 144 LEU D CA 1 ATOM 4296 C C . LEU D 1 144 ? 105.658 26.069 10.174 1.00 51.66 ? 144 LEU D C 1 ATOM 4297 O O . LEU D 1 144 ? 105.614 26.846 11.122 1.00 55.14 ? 144 LEU D O 1 ATOM 4298 C CB . LEU D 1 144 ? 104.319 24.172 9.296 1.00 52.45 ? 144 LEU D CB 1 ATOM 4299 C CG . LEU D 1 144 ? 104.025 22.682 9.159 1.00 48.85 ? 144 LEU D CG 1 ATOM 4300 C CD1 . LEU D 1 144 ? 103.165 22.447 7.932 1.00 44.57 ? 144 LEU D CD1 1 ATOM 4301 C CD2 . LEU D 1 144 ? 105.328 21.932 9.030 1.00 50.50 ? 144 LEU D CD2 1 ATOM 4302 N N . PHE D 1 145 ? 106.001 26.452 8.953 1.00 52.86 ? 145 PHE D N 1 ATOM 4303 C CA . PHE D 1 145 ? 106.357 27.840 8.715 1.00 55.01 ? 145 PHE D CA 1 ATOM 4304 C C . PHE D 1 145 ? 105.758 28.369 7.437 1.00 56.77 ? 145 PHE D C 1 ATOM 4305 O O . PHE D 1 145 ? 105.492 27.613 6.507 1.00 59.71 ? 145 PHE D O 1 ATOM 4306 C CB . PHE D 1 145 ? 107.879 28.013 8.704 1.00 54.86 ? 145 PHE D CB 1 ATOM 4307 C CG . PHE D 1 145 ? 108.513 27.781 10.043 1.00 54.56 ? 145 PHE D CG 1 ATOM 4308 C CD1 . PHE D 1 145 ? 109.259 26.636 10.288 1.00 56.16 ? 145 PHE D CD1 1 ATOM 4309 C CD2 . PHE D 1 145 ? 108.304 28.676 11.085 1.00 53.74 ? 145 PHE D CD2 1 ATOM 4310 C CE1 . PHE D 1 145 ? 109.783 26.381 11.557 1.00 56.86 ? 145 PHE D CE1 1 ATOM 4311 C CE2 . PHE D 1 145 ? 108.823 28.428 12.355 1.00 54.60 ? 145 PHE D CE2 1 ATOM 4312 C CZ . PHE D 1 145 ? 109.564 27.278 12.590 1.00 53.99 ? 145 PHE D CZ 1 ATOM 4313 N N . ARG D 1 146 ? 105.537 29.678 7.412 1.00 57.09 ? 146 ARG D N 1 ATOM 4314 C CA . ARG D 1 146 ? 104.953 30.350 6.266 1.00 56.68 ? 146 ARG D CA 1 ATOM 4315 C C . ARG D 1 146 ? 105.875 31.498 5.889 1.00 56.22 ? 146 ARG D C 1 ATOM 4316 O O . ARG D 1 146 ? 106.552 32.059 6.752 1.00 57.12 ? 146 ARG D O 1 ATOM 4317 C CB . ARG D 1 146 ? 103.570 30.867 6.650 1.00 59.61 ? 146 ARG D CB 1 ATOM 4318 C CG . ARG D 1 146 ? 102.745 31.351 5.489 1.00 67.04 ? 146 ARG D CG 1 ATOM 4319 C CD . ARG D 1 146 ? 101.249 31.339 5.812 1.00 74.80 ? 146 ARG D CD 1 ATOM 4320 N NE . ARG D 1 146 ? 100.866 32.297 6.844 1.00 81.27 ? 146 ARG D NE 1 ATOM 4321 C CZ . ARG D 1 146 ? 99.607 32.613 7.136 1.00 84.13 ? 146 ARG D CZ 1 ATOM 4322 N NH1 . ARG D 1 146 ? 98.606 32.045 6.469 1.00 83.05 ? 146 ARG D NH1 1 ATOM 4323 N NH2 . ARG D 1 146 ? 99.349 33.497 8.093 1.00 85.26 ? 146 ARG D NH2 1 ATOM 4324 N N . LYS D 1 147 ? 105.915 31.848 4.609 1.00 55.87 ? 147 LYS D N 1 ATOM 4325 C CA . LYS D 1 147 ? 106.785 32.940 4.167 1.00 56.86 ? 147 LYS D CA 1 ATOM 4326 C C . LYS D 1 147 ? 106.365 33.504 2.812 1.00 56.51 ? 147 LYS D C 1 ATOM 4327 O O . LYS D 1 147 ? 106.018 32.752 1.897 1.00 56.20 ? 147 LYS D O 1 ATOM 4328 C CB . LYS D 1 147 ? 108.244 32.450 4.114 1.00 58.62 ? 147 LYS D CB 1 ATOM 4329 C CG . LYS D 1 147 ? 109.283 33.481 3.636 1.00 54.60 ? 147 LYS D CG 1 ATOM 4330 C CD . LYS D 1 147 ? 110.716 32.971 3.836 1.00 44.17 ? 147 LYS D CD 1 ATOM 4331 C CE . LYS D 1 147 ? 111.735 33.925 3.248 1.00 37.38 ? 147 LYS D CE 1 ATOM 4332 N NZ . LYS D 1 147 ? 111.522 34.071 1.786 1.00 31.33 ? 147 LYS D NZ 1 ATOM 4333 N N . PHE D 1 148 ? 106.401 34.832 2.695 1.00 55.41 ? 148 PHE D N 1 ATOM 4334 C CA . PHE D 1 148 ? 106.019 35.505 1.460 1.00 55.58 ? 148 PHE D CA 1 ATOM 4335 C C . PHE D 1 148 ? 107.195 36.128 0.724 1.00 56.97 ? 148 PHE D C 1 ATOM 4336 O O . PHE D 1 148 ? 108.235 36.418 1.311 1.00 55.61 ? 148 PHE D O 1 ATOM 4337 C CB . PHE D 1 148 ? 105.013 36.616 1.733 1.00 54.46 ? 148 PHE D CB 1 ATOM 4338 C CG . PHE D 1 148 ? 103.795 36.180 2.495 1.00 53.42 ? 148 PHE D CG 1 ATOM 4339 C CD1 . PHE D 1 148 ? 103.853 35.974 3.869 1.00 53.96 ? 148 PHE D CD1 1 ATOM 4340 C CD2 . PHE D 1 148 ? 102.569 36.036 1.845 1.00 53.20 ? 148 PHE D CD2 1 ATOM 4341 C CE1 . PHE D 1 148 ? 102.706 35.637 4.587 1.00 54.54 ? 148 PHE D CE1 1 ATOM 4342 C CE2 . PHE D 1 148 ? 101.417 35.699 2.549 1.00 50.83 ? 148 PHE D CE2 1 ATOM 4343 C CZ . PHE D 1 148 ? 101.484 35.500 3.923 1.00 53.90 ? 148 PHE D CZ 1 ATOM 4344 N N . HIS D 1 149 ? 107.000 36.338 -0.574 1.00 59.95 ? 149 HIS D N 1 ATOM 4345 C CA . HIS D 1 149 ? 108.003 36.949 -1.440 1.00 64.47 ? 149 HIS D CA 1 ATOM 4346 C C . HIS D 1 149 ? 107.274 37.835 -2.426 1.00 64.56 ? 149 HIS D C 1 ATOM 4347 O O . HIS D 1 149 ? 106.326 37.391 -3.073 1.00 67.25 ? 149 HIS D O 1 ATOM 4348 C CB . HIS D 1 149 ? 108.781 35.897 -2.209 1.00 69.79 ? 149 HIS D CB 1 ATOM 4349 C CG . HIS D 1 149 ? 110.239 35.905 -1.903 1.00 76.42 ? 149 HIS D CG 1 ATOM 4350 N ND1 . HIS D 1 149 ? 110.761 35.327 -0.766 1.00 77.53 ? 149 HIS D ND1 1 ATOM 4351 C CD2 . HIS D 1 149 ? 111.283 36.460 -2.561 1.00 80.19 ? 149 HIS D CD2 1 ATOM 4352 C CE1 . HIS D 1 149 ? 112.067 35.525 -0.738 1.00 81.50 ? 149 HIS D CE1 1 ATOM 4353 N NE2 . HIS D 1 149 ? 112.409 36.212 -1.815 1.00 82.81 ? 149 HIS D NE2 1 ATOM 4354 N N . TYR D 1 150 ? 107.725 39.075 -2.570 1.00 60.37 ? 150 TYR D N 1 ATOM 4355 C CA . TYR D 1 150 ? 107.033 39.998 -3.449 1.00 54.73 ? 150 TYR D CA 1 ATOM 4356 C C . TYR D 1 150 ? 107.842 40.458 -4.621 1.00 51.86 ? 150 TYR D C 1 ATOM 4357 O O . TYR D 1 150 ? 109.053 40.502 -4.550 1.00 53.54 ? 150 TYR D O 1 ATOM 4358 C CB . TYR D 1 150 ? 106.617 41.201 -2.642 1.00 53.41 ? 150 TYR D CB 1 ATOM 4359 C CG . TYR D 1 150 ? 106.003 40.836 -1.320 1.00 53.06 ? 150 TYR D CG 1 ATOM 4360 C CD1 . TYR D 1 150 ? 104.628 40.654 -1.196 1.00 52.52 ? 150 TYR D CD1 1 ATOM 4361 C CD2 . TYR D 1 150 ? 106.788 40.740 -0.174 1.00 51.69 ? 150 TYR D CD2 1 ATOM 4362 C CE1 . TYR D 1 150 ? 104.043 40.405 0.046 1.00 54.12 ? 150 TYR D CE1 1 ATOM 4363 C CE2 . TYR D 1 150 ? 106.215 40.491 1.073 1.00 53.55 ? 150 TYR D CE2 1 ATOM 4364 C CZ . TYR D 1 150 ? 104.839 40.335 1.181 1.00 54.25 ? 150 TYR D CZ 1 ATOM 4365 O OH . TYR D 1 150 ? 104.253 40.191 2.428 1.00 54.14 ? 150 TYR D OH 1 ATOM 4366 N N . LEU D 1 151 ? 107.167 40.813 -5.702 1.00 49.34 ? 151 LEU D N 1 ATOM 4367 C CA . LEU D 1 151 ? 107.867 41.293 -6.875 1.00 52.24 ? 151 LEU D CA 1 ATOM 4368 C C . LEU D 1 151 ? 107.044 42.307 -7.630 1.00 55.34 ? 151 LEU D C 1 ATOM 4369 O O . LEU D 1 151 ? 106.031 41.955 -8.231 1.00 59.13 ? 151 LEU D O 1 ATOM 4370 C CB . LEU D 1 151 ? 108.191 40.159 -7.846 1.00 51.15 ? 151 LEU D CB 1 ATOM 4371 C CG . LEU D 1 151 ? 108.927 40.692 -9.091 1.00 50.58 ? 151 LEU D CG 1 ATOM 4372 C CD1 . LEU D 1 151 ? 110.412 40.750 -8.753 1.00 52.95 ? 151 LEU D CD1 1 ATOM 4373 C CD2 . LEU D 1 151 ? 108.688 39.824 -10.334 1.00 44.58 ? 151 LEU D CD2 1 ATOM 4374 N N . PRO D 1 152 ? 107.458 43.584 -7.612 1.00 55.74 ? 152 PRO D N 1 ATOM 4375 C CA . PRO D 1 152 ? 106.657 44.558 -8.360 1.00 53.81 ? 152 PRO D CA 1 ATOM 4376 C C . PRO D 1 152 ? 106.863 44.264 -9.839 1.00 53.15 ? 152 PRO D C 1 ATOM 4377 O O . PRO D 1 152 ? 107.877 43.683 -10.225 1.00 52.38 ? 152 PRO D O 1 ATOM 4378 C CB . PRO D 1 152 ? 107.257 45.893 -7.943 1.00 52.38 ? 152 PRO D CB 1 ATOM 4379 C CG . PRO D 1 152 ? 107.777 45.604 -6.557 1.00 54.55 ? 152 PRO D CG 1 ATOM 4380 C CD . PRO D 1 152 ? 108.422 44.260 -6.728 1.00 53.16 ? 152 PRO D CD 1 ATOM 4381 N N . PHE D 1 153 ? 105.905 44.643 -10.667 1.00 53.11 ? 153 PHE D N 1 ATOM 4382 C CA . PHE D 1 153 ? 106.046 44.391 -12.087 1.00 56.58 ? 153 PHE D CA 1 ATOM 4383 C C . PHE D 1 153 ? 105.037 45.177 -12.912 1.00 56.39 ? 153 PHE D C 1 ATOM 4384 O O . PHE D 1 153 ? 104.067 45.718 -12.380 1.00 56.26 ? 153 PHE D O 1 ATOM 4385 C CB . PHE D 1 153 ? 105.896 42.895 -12.376 1.00 61.30 ? 153 PHE D CB 1 ATOM 4386 C CG . PHE D 1 153 ? 104.488 42.382 -12.227 1.00 68.00 ? 153 PHE D CG 1 ATOM 4387 C CD1 . PHE D 1 153 ? 103.957 42.109 -10.966 1.00 68.33 ? 153 PHE D CD1 1 ATOM 4388 C CD2 . PHE D 1 153 ? 103.684 42.183 -13.356 1.00 70.04 ? 153 PHE D CD2 1 ATOM 4389 C CE1 . PHE D 1 153 ? 102.644 41.643 -10.830 1.00 70.54 ? 153 PHE D CE1 1 ATOM 4390 C CE2 . PHE D 1 153 ? 102.370 41.718 -13.232 1.00 70.26 ? 153 PHE D CE2 1 ATOM 4391 C CZ . PHE D 1 153 ? 101.849 41.447 -11.968 1.00 71.45 ? 153 PHE D CZ 1 ATOM 4392 N N . LEU D 1 154 ? 105.268 45.228 -14.218 1.00 56.35 ? 154 LEU D N 1 ATOM 4393 C CA . LEU D 1 154 ? 104.382 45.955 -15.107 1.00 57.35 ? 154 LEU D CA 1 ATOM 4394 C C . LEU D 1 154 ? 103.745 45.019 -16.120 1.00 58.32 ? 154 LEU D C 1 ATOM 4395 O O . LEU D 1 154 ? 104.387 44.569 -17.072 1.00 59.20 ? 154 LEU D O 1 ATOM 4396 C CB . LEU D 1 154 ? 105.152 47.061 -15.826 1.00 58.00 ? 154 LEU D CB 1 ATOM 4397 C CG . LEU D 1 154 ? 104.314 48.226 -16.349 1.00 57.85 ? 154 LEU D CG 1 ATOM 4398 C CD1 . LEU D 1 154 ? 103.627 48.923 -15.180 1.00 59.00 ? 154 LEU D CD1 1 ATOM 4399 C CD2 . LEU D 1 154 ? 105.207 49.204 -17.091 1.00 58.07 ? 154 LEU D CD2 1 ATOM 4400 N N . PRO D 1 155 ? 102.462 44.710 -15.915 1.00 59.45 ? 155 PRO D N 1 ATOM 4401 C CA . PRO D 1 155 ? 101.672 43.831 -16.771 1.00 61.60 ? 155 PRO D CA 1 ATOM 4402 C C . PRO D 1 155 ? 102.049 43.887 -18.246 1.00 62.54 ? 155 PRO D C 1 ATOM 4403 O O . PRO D 1 155 ? 101.634 44.790 -18.970 1.00 63.81 ? 155 PRO D O 1 ATOM 4404 C CB . PRO D 1 155 ? 100.253 44.305 -16.503 1.00 61.43 ? 155 PRO D CB 1 ATOM 4405 C CG . PRO D 1 155 ? 100.306 44.550 -15.029 1.00 61.54 ? 155 PRO D CG 1 ATOM 4406 C CD . PRO D 1 155 ? 101.635 45.250 -14.821 1.00 59.74 ? 155 PRO D CD 1 ATOM 4407 N N . SER D 1 156 ? 102.846 42.914 -18.677 1.00 62.14 ? 156 SER D N 1 ATOM 4408 C CA . SER D 1 156 ? 103.273 42.822 -20.067 1.00 62.99 ? 156 SER D CA 1 ATOM 4409 C C . SER D 1 156 ? 102.653 41.582 -20.680 1.00 62.35 ? 156 SER D C 1 ATOM 4410 O O . SER D 1 156 ? 102.880 40.480 -20.196 1.00 64.33 ? 156 SER D O 1 ATOM 4411 C CB . SER D 1 156 ? 104.790 42.705 -20.150 1.00 64.17 ? 156 SER D CB 1 ATOM 4412 O OG . SER D 1 156 ? 105.176 42.325 -21.461 1.00 65.52 ? 156 SER D OG 1 ATOM 4413 N N . THR D 1 157 ? 101.880 41.738 -21.745 1.00 61.26 ? 157 THR D N 1 ATOM 4414 C CA . THR D 1 157 ? 101.266 40.564 -22.344 1.00 62.94 ? 157 THR D CA 1 ATOM 4415 C C . THR D 1 157 ? 102.296 39.780 -23.140 1.00 62.59 ? 157 THR D C 1 ATOM 4416 O O . THR D 1 157 ? 101.954 38.909 -23.939 1.00 63.84 ? 157 THR D O 1 ATOM 4417 C CB . THR D 1 157 ? 100.104 40.926 -23.278 1.00 65.30 ? 157 THR D CB 1 ATOM 4418 O OG1 . THR D 1 157 ? 100.555 40.882 -24.635 1.00 68.92 ? 157 THR D OG1 1 ATOM 4419 C CG2 . THR D 1 157 ? 99.583 42.318 -22.966 1.00 69.05 ? 157 THR D CG2 1 ATOM 4420 N N . GLU D 1 158 ? 103.563 40.099 -22.927 1.00 62.91 ? 158 GLU D N 1 ATOM 4421 C CA . GLU D 1 158 ? 104.635 39.401 -23.621 1.00 63.32 ? 158 GLU D CA 1 ATOM 4422 C C . GLU D 1 158 ? 105.561 38.824 -22.578 1.00 60.33 ? 158 GLU D C 1 ATOM 4423 O O . GLU D 1 158 ? 106.730 38.582 -22.844 1.00 60.48 ? 158 GLU D O 1 ATOM 4424 C CB . GLU D 1 158 ? 105.429 40.353 -24.523 1.00 69.34 ? 158 GLU D CB 1 ATOM 4425 C CG . GLU D 1 158 ? 104.657 40.931 -25.710 1.00 72.20 ? 158 GLU D CG 1 ATOM 4426 C CD . GLU D 1 158 ? 104.265 39.882 -26.726 1.00 71.56 ? 158 GLU D CD 1 ATOM 4427 O OE1 . GLU D 1 158 ? 105.155 39.110 -27.146 1.00 72.58 ? 158 GLU D OE1 1 ATOM 4428 O OE2 . GLU D 1 158 ? 103.073 39.840 -27.106 1.00 69.96 ? 158 GLU D OE2 1 ATOM 4429 N N . ASP D 1 159 ? 105.048 38.627 -21.375 1.00 58.41 ? 159 ASP D N 1 ATOM 4430 C CA . ASP D 1 159 ? 105.881 38.058 -20.340 1.00 58.72 ? 159 ASP D CA 1 ATOM 4431 C C . ASP D 1 159 ? 105.379 36.770 -19.730 1.00 59.48 ? 159 ASP D C 1 ATOM 4432 O O . ASP D 1 159 ? 104.355 36.214 -20.134 1.00 60.71 ? 159 ASP D O 1 ATOM 4433 C CB . ASP D 1 159 ? 106.162 39.077 -19.251 1.00 57.39 ? 159 ASP D CB 1 ATOM 4434 C CG . ASP D 1 159 ? 107.078 40.152 -19.725 1.00 59.45 ? 159 ASP D CG 1 ATOM 4435 O OD1 . ASP D 1 159 ? 107.752 40.779 -18.883 1.00 66.50 ? 159 ASP D OD1 1 ATOM 4436 O OD2 . ASP D 1 159 ? 107.120 40.366 -20.955 1.00 56.28 ? 159 ASP D OD2 1 ATOM 4437 N N . VAL D 1 160 ? 106.127 36.306 -18.741 1.00 57.23 ? 160 VAL D N 1 ATOM 4438 C CA . VAL D 1 160 ? 105.842 35.058 -18.084 1.00 52.31 ? 160 VAL D CA 1 ATOM 4439 C C . VAL D 1 160 ? 106.706 35.051 -16.842 1.00 53.77 ? 160 VAL D C 1 ATOM 4440 O O . VAL D 1 160 ? 107.903 35.302 -16.923 1.00 55.11 ? 160 VAL D O 1 ATOM 4441 C CB . VAL D 1 160 ? 106.252 33.911 -19.008 1.00 48.95 ? 160 VAL D CB 1 ATOM 4442 C CG1 . VAL D 1 160 ? 106.870 32.801 -18.210 1.00 53.13 ? 160 VAL D CG1 1 ATOM 4443 C CG2 . VAL D 1 160 ? 105.061 33.429 -19.809 1.00 43.96 ? 160 VAL D CG2 1 ATOM 4444 N N . TYR D 1 161 ? 106.102 34.781 -15.691 1.00 55.66 ? 161 TYR D N 1 ATOM 4445 C CA . TYR D 1 161 ? 106.846 34.745 -14.433 1.00 54.58 ? 161 TYR D CA 1 ATOM 4446 C C . TYR D 1 161 ? 106.643 33.412 -13.747 1.00 51.74 ? 161 TYR D C 1 ATOM 4447 O O . TYR D 1 161 ? 105.638 32.732 -13.958 1.00 51.59 ? 161 TYR D O 1 ATOM 4448 C CB . TYR D 1 161 ? 106.379 35.847 -13.479 1.00 55.77 ? 161 TYR D CB 1 ATOM 4449 C CG . TYR D 1 161 ? 106.469 37.227 -14.056 1.00 58.12 ? 161 TYR D CG 1 ATOM 4450 C CD1 . TYR D 1 161 ? 105.861 37.527 -15.274 1.00 60.00 ? 161 TYR D CD1 1 ATOM 4451 C CD2 . TYR D 1 161 ? 107.157 38.237 -13.389 1.00 59.93 ? 161 TYR D CD2 1 ATOM 4452 C CE1 . TYR D 1 161 ? 105.932 38.788 -15.821 1.00 64.99 ? 161 TYR D CE1 1 ATOM 4453 C CE2 . TYR D 1 161 ? 107.237 39.513 -13.923 1.00 65.54 ? 161 TYR D CE2 1 ATOM 4454 C CZ . TYR D 1 161 ? 106.620 39.782 -15.146 1.00 69.01 ? 161 TYR D CZ 1 ATOM 4455 O OH . TYR D 1 161 ? 106.685 41.041 -15.702 1.00 74.65 ? 161 TYR D OH 1 ATOM 4456 N N . ASP D 1 162 ? 107.612 33.040 -12.929 1.00 46.91 ? 162 ASP D N 1 ATOM 4457 C CA . ASP D 1 162 ? 107.521 31.809 -12.188 1.00 42.52 ? 162 ASP D CA 1 ATOM 4458 C C . ASP D 1 162 ? 108.154 32.138 -10.867 1.00 43.58 ? 162 ASP D C 1 ATOM 4459 O O . ASP D 1 162 ? 108.911 33.103 -10.760 1.00 43.67 ? 162 ASP D O 1 ATOM 4460 C CB . ASP D 1 162 ? 108.282 30.691 -12.895 1.00 37.66 ? 162 ASP D CB 1 ATOM 4461 C CG . ASP D 1 162 ? 107.704 30.371 -14.263 1.00 39.43 ? 162 ASP D CG 1 ATOM 4462 O OD1 . ASP D 1 162 ? 106.554 29.899 -14.344 1.00 33.00 ? 162 ASP D OD1 1 ATOM 4463 O OD2 . ASP D 1 162 ? 108.397 30.601 -15.271 1.00 45.46 ? 162 ASP D OD2 1 ATOM 4464 N N . CYS D 1 163 ? 107.803 31.367 -9.852 1.00 45.41 ? 163 CYS D N 1 ATOM 4465 C CA . CYS D 1 163 ? 108.363 31.555 -8.532 1.00 49.50 ? 163 CYS D CA 1 ATOM 4466 C C . CYS D 1 163 ? 109.041 30.240 -8.214 1.00 53.46 ? 163 CYS D C 1 ATOM 4467 O O . CYS D 1 163 ? 108.366 29.285 -7.843 1.00 57.42 ? 163 CYS D O 1 ATOM 4468 C CB . CYS D 1 163 ? 107.266 31.821 -7.499 1.00 48.25 ? 163 CYS D CB 1 ATOM 4469 S SG . CYS D 1 163 ? 107.979 31.886 -5.829 1.00 53.97 ? 163 CYS D SG 1 ATOM 4470 N N . ARG D 1 164 ? 110.358 30.163 -8.385 1.00 56.09 ? 164 ARG D N 1 ATOM 4471 C CA . ARG D 1 164 ? 111.056 28.915 -8.091 1.00 57.83 ? 164 ARG D CA 1 ATOM 4472 C C . ARG D 1 164 ? 111.318 28.803 -6.612 1.00 57.48 ? 164 ARG D C 1 ATOM 4473 O O . ARG D 1 164 ? 112.009 29.634 -6.034 1.00 57.23 ? 164 ARG D O 1 ATOM 4474 C CB . ARG D 1 164 ? 112.391 28.822 -8.825 1.00 62.06 ? 164 ARG D CB 1 ATOM 4475 C CG . ARG D 1 164 ? 113.485 28.175 -7.969 1.00 68.44 ? 164 ARG D CG 1 ATOM 4476 C CD . ARG D 1 164 ? 114.349 27.211 -8.750 1.00 71.78 ? 164 ARG D CD 1 ATOM 4477 N NE . ARG D 1 164 ? 114.953 27.834 -9.918 1.00 72.56 ? 164 ARG D NE 1 ATOM 4478 C CZ . ARG D 1 164 ? 115.606 27.158 -10.853 1.00 73.63 ? 164 ARG D CZ 1 ATOM 4479 N NH1 . ARG D 1 164 ? 115.736 25.843 -10.745 1.00 74.86 ? 164 ARG D NH1 1 ATOM 4480 N NH2 . ARG D 1 164 ? 116.116 27.793 -11.898 1.00 74.67 ? 164 ARG D NH2 1 ATOM 4481 N N . VAL D 1 165 ? 110.766 27.771 -5.997 1.00 58.15 ? 165 VAL D N 1 ATOM 4482 C CA . VAL D 1 165 ? 110.969 27.572 -4.578 1.00 61.38 ? 165 VAL D CA 1 ATOM 4483 C C . VAL D 1 165 ? 111.487 26.170 -4.385 1.00 63.67 ? 165 VAL D C 1 ATOM 4484 O O . VAL D 1 165 ? 111.018 25.232 -5.030 1.00 63.93 ? 165 VAL D O 1 ATOM 4485 C CB . VAL D 1 165 ? 109.666 27.743 -3.786 1.00 61.59 ? 165 VAL D CB 1 ATOM 4486 C CG1 . VAL D 1 165 ? 109.942 27.633 -2.294 1.00 60.78 ? 165 VAL D CG1 1 ATOM 4487 C CG2 . VAL D 1 165 ? 109.048 29.086 -4.101 1.00 63.68 ? 165 VAL D CG2 1 ATOM 4488 N N . GLU D 1 166 ? 112.464 26.035 -3.498 1.00 65.36 ? 166 GLU D N 1 ATOM 4489 C CA . GLU D 1 166 ? 113.056 24.744 -3.227 1.00 67.23 ? 166 GLU D CA 1 ATOM 4490 C C . GLU D 1 166 ? 113.282 24.572 -1.733 1.00 67.09 ? 166 GLU D C 1 ATOM 4491 O O . GLU D 1 166 ? 113.806 25.463 -1.064 1.00 64.11 ? 166 GLU D O 1 ATOM 4492 C CB . GLU D 1 166 ? 114.367 24.625 -3.985 1.00 70.66 ? 166 GLU D CB 1 ATOM 4493 C CG . GLU D 1 166 ? 115.373 25.667 -3.572 1.00 79.16 ? 166 GLU D CG 1 ATOM 4494 C CD . GLU D 1 166 ? 116.568 25.718 -4.496 1.00 85.01 ? 166 GLU D CD 1 ATOM 4495 O OE1 . GLU D 1 166 ? 117.605 26.280 -4.082 1.00 87.88 ? 166 GLU D OE1 1 ATOM 4496 O OE2 . GLU D 1 166 ? 116.466 25.208 -5.636 1.00 87.66 ? 166 GLU D OE2 1 ATOM 4497 N N . HIS D 1 167 ? 112.859 23.411 -1.236 1.00 69.52 ? 167 HIS D N 1 ATOM 4498 C CA . HIS D 1 167 ? 112.955 23.013 0.170 1.00 72.39 ? 167 HIS D CA 1 ATOM 4499 C C . HIS D 1 167 ? 113.430 21.568 0.103 1.00 74.19 ? 167 HIS D C 1 ATOM 4500 O O . HIS D 1 167 ? 113.202 20.894 -0.901 1.00 76.10 ? 167 HIS D O 1 ATOM 4501 C CB . HIS D 1 167 ? 111.564 23.097 0.824 1.00 72.31 ? 167 HIS D CB 1 ATOM 4502 C CG . HIS D 1 167 ? 111.536 22.749 2.283 1.00 73.26 ? 167 HIS D CG 1 ATOM 4503 N ND1 . HIS D 1 167 ? 112.476 23.207 3.183 1.00 76.16 ? 167 HIS D ND1 1 ATOM 4504 C CD2 . HIS D 1 167 ? 110.640 22.037 3.008 1.00 72.54 ? 167 HIS D CD2 1 ATOM 4505 C CE1 . HIS D 1 167 ? 112.160 22.793 4.398 1.00 74.07 ? 167 HIS D CE1 1 ATOM 4506 N NE2 . HIS D 1 167 ? 111.050 22.082 4.319 1.00 73.31 ? 167 HIS D NE2 1 ATOM 4507 N N . TRP D 1 168 ? 114.088 21.089 1.153 1.00 75.62 ? 168 TRP D N 1 ATOM 4508 C CA . TRP D 1 168 ? 114.590 19.718 1.159 1.00 76.97 ? 168 TRP D CA 1 ATOM 4509 C C . TRP D 1 168 ? 113.500 18.647 1.123 1.00 78.63 ? 168 TRP D C 1 ATOM 4510 O O . TRP D 1 168 ? 113.790 17.452 1.125 1.00 78.67 ? 168 TRP D O 1 ATOM 4511 C CB . TRP D 1 168 ? 115.489 19.505 2.373 1.00 75.90 ? 168 TRP D CB 1 ATOM 4512 C CG . TRP D 1 168 ? 116.631 20.452 2.399 1.00 76.18 ? 168 TRP D CG 1 ATOM 4513 C CD1 . TRP D 1 168 ? 117.440 20.784 1.352 1.00 77.36 ? 168 TRP D CD1 1 ATOM 4514 C CD2 . TRP D 1 168 ? 117.102 21.195 3.523 1.00 76.21 ? 168 TRP D CD2 1 ATOM 4515 N NE1 . TRP D 1 168 ? 118.387 21.694 1.754 1.00 78.26 ? 168 TRP D NE1 1 ATOM 4516 C CE2 . TRP D 1 168 ? 118.204 21.963 3.084 1.00 76.54 ? 168 TRP D CE2 1 ATOM 4517 C CE3 . TRP D 1 168 ? 116.703 21.287 4.861 1.00 76.27 ? 168 TRP D CE3 1 ATOM 4518 C CZ2 . TRP D 1 168 ? 118.912 22.813 3.933 1.00 75.07 ? 168 TRP D CZ2 1 ATOM 4519 C CZ3 . TRP D 1 168 ? 117.407 22.130 5.705 1.00 77.08 ? 168 TRP D CZ3 1 ATOM 4520 C CH2 . TRP D 1 168 ? 118.500 22.883 5.237 1.00 76.43 ? 168 TRP D CH2 1 ATOM 4521 N N . GLY D 1 169 ? 112.245 19.076 1.086 1.00 80.70 ? 169 GLY D N 1 ATOM 4522 C CA . GLY D 1 169 ? 111.155 18.123 1.044 1.00 81.17 ? 169 GLY D CA 1 ATOM 4523 C C . GLY D 1 169 ? 110.857 17.739 -0.387 1.00 81.70 ? 169 GLY D C 1 ATOM 4524 O O . GLY D 1 169 ? 110.289 16.684 -0.654 1.00 82.50 ? 169 GLY D O 1 ATOM 4525 N N . LEU D 1 170 ? 111.242 18.602 -1.316 1.00 81.92 ? 170 LEU D N 1 ATOM 4526 C CA . LEU D 1 170 ? 111.007 18.340 -2.723 1.00 84.84 ? 170 LEU D CA 1 ATOM 4527 C C . LEU D 1 170 ? 112.201 17.632 -3.346 1.00 88.80 ? 170 LEU D C 1 ATOM 4528 O O . LEU D 1 170 ? 113.296 17.626 -2.783 1.00 89.28 ? 170 LEU D O 1 ATOM 4529 C CB . LEU D 1 170 ? 110.748 19.651 -3.458 1.00 82.48 ? 170 LEU D CB 1 ATOM 4530 C CG . LEU D 1 170 ? 109.537 20.435 -2.968 1.00 80.97 ? 170 LEU D CG 1 ATOM 4531 C CD1 . LEU D 1 170 ? 109.484 21.775 -3.668 1.00 80.95 ? 170 LEU D CD1 1 ATOM 4532 C CD2 . LEU D 1 170 ? 108.278 19.632 -3.237 1.00 81.28 ? 170 LEU D CD2 1 ATOM 4533 N N . ASP D 1 171 ? 111.975 17.035 -4.511 1.00 92.24 ? 171 ASP D N 1 ATOM 4534 C CA . ASP D 1 171 ? 113.018 16.325 -5.241 1.00 96.25 ? 171 ASP D CA 1 ATOM 4535 C C . ASP D 1 171 ? 113.639 17.318 -6.206 1.00 96.80 ? 171 ASP D C 1 ATOM 4536 O O . ASP D 1 171 ? 114.831 17.629 -6.142 1.00 97.80 ? 171 ASP D O 1 ATOM 4537 C CB . ASP D 1 171 ? 112.400 15.187 -6.040 1.00 100.60 ? 171 ASP D CB 1 ATOM 4538 C CG . ASP D 1 171 ? 111.261 14.526 -5.309 1.00 106.97 ? 171 ASP D CG 1 ATOM 4539 O OD1 . ASP D 1 171 ? 111.517 13.922 -4.246 1.00 110.38 ? 171 ASP D OD1 1 ATOM 4540 O OD2 . ASP D 1 171 ? 110.111 14.620 -5.794 1.00 111.41 ? 171 ASP D OD2 1 ATOM 4541 N N . GLU D 1 172 ? 112.796 17.801 -7.108 1.00 96.32 ? 172 GLU D N 1 ATOM 4542 C CA . GLU D 1 172 ? 113.178 18.774 -8.115 1.00 95.97 ? 172 GLU D CA 1 ATOM 4543 C C . GLU D 1 172 ? 112.500 20.091 -7.742 1.00 93.03 ? 172 GLU D C 1 ATOM 4544 O O . GLU D 1 172 ? 111.273 20.177 -7.736 1.00 93.21 ? 172 GLU D O 1 ATOM 4545 C CB . GLU D 1 172 ? 112.707 18.285 -9.488 1.00 99.43 ? 172 GLU D CB 1 ATOM 4546 C CG . GLU D 1 172 ? 111.317 17.647 -9.461 1.00 104.07 ? 172 GLU D CG 1 ATOM 4547 C CD . GLU D 1 172 ? 110.950 16.966 -10.770 1.00 107.33 ? 172 GLU D CD 1 ATOM 4548 O OE1 . GLU D 1 172 ? 111.717 16.088 -11.221 1.00 109.00 ? 172 GLU D OE1 1 ATOM 4549 O OE2 . GLU D 1 172 ? 109.892 17.303 -11.345 1.00 107.98 ? 172 GLU D OE2 1 ATOM 4550 N N . PRO D 1 173 ? 113.294 21.130 -7.417 1.00 90.03 ? 173 PRO D N 1 ATOM 4551 C CA . PRO D 1 173 ? 112.784 22.448 -7.036 1.00 87.51 ? 173 PRO D CA 1 ATOM 4552 C C . PRO D 1 173 ? 111.465 22.758 -7.710 1.00 84.89 ? 173 PRO D C 1 ATOM 4553 O O . PRO D 1 173 ? 111.212 22.318 -8.832 1.00 85.60 ? 173 PRO D O 1 ATOM 4554 C CB . PRO D 1 173 ? 113.899 23.380 -7.473 1.00 89.08 ? 173 PRO D CB 1 ATOM 4555 C CG . PRO D 1 173 ? 115.096 22.587 -7.130 1.00 91.95 ? 173 PRO D CG 1 ATOM 4556 C CD . PRO D 1 173 ? 114.747 21.197 -7.646 1.00 91.30 ? 173 PRO D CD 1 ATOM 4557 N N . LEU D 1 174 ? 110.633 23.530 -7.024 1.00 80.26 ? 174 LEU D N 1 ATOM 4558 C CA . LEU D 1 174 ? 109.318 23.861 -7.537 1.00 73.79 ? 174 LEU D CA 1 ATOM 4559 C C . LEU D 1 174 ? 109.208 25.181 -8.297 1.00 71.67 ? 174 LEU D C 1 ATOM 4560 O O . LEU D 1 174 ? 109.880 26.169 -7.980 1.00 69.04 ? 174 LEU D O 1 ATOM 4561 C CB . LEU D 1 174 ? 108.324 23.840 -6.379 1.00 71.82 ? 174 LEU D CB 1 ATOM 4562 C CG . LEU D 1 174 ? 106.895 23.444 -6.731 1.00 69.97 ? 174 LEU D CG 1 ATOM 4563 C CD1 . LEU D 1 174 ? 106.910 22.147 -7.520 1.00 69.38 ? 174 LEU D CD1 1 ATOM 4564 C CD2 . LEU D 1 174 ? 106.085 23.298 -5.454 1.00 68.76 ? 174 LEU D CD2 1 ATOM 4565 N N . LEU D 1 175 ? 108.350 25.172 -9.314 1.00 70.30 ? 175 LEU D N 1 ATOM 4566 C CA . LEU D 1 175 ? 108.088 26.344 -10.144 1.00 66.91 ? 175 LEU D CA 1 ATOM 4567 C C . LEU D 1 175 ? 106.599 26.630 -10.212 1.00 64.50 ? 175 LEU D C 1 ATOM 4568 O O . LEU D 1 175 ? 105.808 25.793 -10.656 1.00 63.75 ? 175 LEU D O 1 ATOM 4569 C CB . LEU D 1 175 ? 108.591 26.148 -11.578 1.00 66.26 ? 175 LEU D CB 1 ATOM 4570 C CG . LEU D 1 175 ? 110.065 26.366 -11.897 1.00 62.81 ? 175 LEU D CG 1 ATOM 4571 C CD1 . LEU D 1 175 ? 110.237 26.377 -13.409 1.00 60.01 ? 175 LEU D CD1 1 ATOM 4572 C CD2 . LEU D 1 175 ? 110.535 27.674 -11.294 1.00 61.10 ? 175 LEU D CD2 1 ATOM 4573 N N . LYS D 1 176 ? 106.226 27.820 -9.770 1.00 61.21 ? 176 LYS D N 1 ATOM 4574 C CA . LYS D 1 176 ? 104.845 28.245 -9.806 1.00 59.57 ? 176 LYS D CA 1 ATOM 4575 C C . LYS D 1 176 ? 104.738 29.319 -10.875 1.00 58.27 ? 176 LYS D C 1 ATOM 4576 O O . LYS D 1 176 ? 105.171 30.446 -10.673 1.00 60.06 ? 176 LYS D O 1 ATOM 4577 C CB . LYS D 1 176 ? 104.442 28.774 -8.436 1.00 60.66 ? 176 LYS D CB 1 ATOM 4578 C CG . LYS D 1 176 ? 103.876 27.688 -7.551 1.00 61.47 ? 176 LYS D CG 1 ATOM 4579 C CD . LYS D 1 176 ? 102.500 27.305 -8.058 1.00 64.39 ? 176 LYS D CD 1 ATOM 4580 C CE . LYS D 1 176 ? 102.006 26.025 -7.437 1.00 66.35 ? 176 LYS D CE 1 ATOM 4581 N NZ . LYS D 1 176 ? 100.573 25.811 -7.760 1.00 69.03 ? 176 LYS D NZ 1 ATOM 4582 N N . HIS D 1 177 ? 104.171 28.947 -12.017 1.00 57.78 ? 177 HIS D N 1 ATOM 4583 C CA . HIS D 1 177 ? 104.018 29.835 -13.171 1.00 60.24 ? 177 HIS D CA 1 ATOM 4584 C C . HIS D 1 177 ? 102.967 30.940 -13.037 1.00 64.16 ? 177 HIS D C 1 ATOM 4585 O O . HIS D 1 177 ? 102.054 30.852 -12.220 1.00 67.82 ? 177 HIS D O 1 ATOM 4586 C CB . HIS D 1 177 ? 103.708 28.980 -14.396 1.00 57.44 ? 177 HIS D CB 1 ATOM 4587 C CG . HIS D 1 177 ? 103.718 29.733 -15.690 1.00 56.52 ? 177 HIS D CG 1 ATOM 4588 N ND1 . HIS D 1 177 ? 104.671 30.680 -15.993 1.00 54.22 ? 177 HIS D ND1 1 ATOM 4589 C CD2 . HIS D 1 177 ? 102.942 29.612 -16.795 1.00 56.13 ? 177 HIS D CD2 1 ATOM 4590 C CE1 . HIS D 1 177 ? 104.482 31.107 -17.229 1.00 56.30 ? 177 HIS D CE1 1 ATOM 4591 N NE2 . HIS D 1 177 ? 103.441 30.473 -17.739 1.00 53.40 ? 177 HIS D NE2 1 ATOM 4592 N N . TRP D 1 178 ? 103.105 31.987 -13.847 1.00 65.96 ? 178 TRP D N 1 ATOM 4593 C CA . TRP D 1 178 ? 102.164 33.103 -13.830 1.00 66.77 ? 178 TRP D CA 1 ATOM 4594 C C . TRP D 1 178 ? 102.277 33.902 -15.124 1.00 67.60 ? 178 TRP D C 1 ATOM 4595 O O . TRP D 1 178 ? 103.373 34.116 -15.637 1.00 66.85 ? 178 TRP D O 1 ATOM 4596 C CB . TRP D 1 178 ? 102.445 34.042 -12.649 1.00 67.59 ? 178 TRP D CB 1 ATOM 4597 C CG . TRP D 1 178 ? 101.379 35.088 -12.469 1.00 69.95 ? 178 TRP D CG 1 ATOM 4598 C CD1 . TRP D 1 178 ? 100.356 35.051 -11.579 1.00 71.81 ? 178 TRP D CD1 1 ATOM 4599 C CD2 . TRP D 1 178 ? 101.162 36.260 -13.278 1.00 70.56 ? 178 TRP D CD2 1 ATOM 4600 N NE1 . TRP D 1 178 ? 99.506 36.114 -11.780 1.00 72.37 ? 178 TRP D NE1 1 ATOM 4601 C CE2 . TRP D 1 178 ? 99.977 36.870 -12.817 1.00 69.98 ? 178 TRP D CE2 1 ATOM 4602 C CE3 . TRP D 1 178 ? 101.849 36.846 -14.347 1.00 69.38 ? 178 TRP D CE3 1 ATOM 4603 C CZ2 . TRP D 1 178 ? 99.461 38.035 -13.387 1.00 67.58 ? 178 TRP D CZ2 1 ATOM 4604 C CZ3 . TRP D 1 178 ? 101.333 38.004 -14.916 1.00 68.61 ? 178 TRP D CZ3 1 ATOM 4605 C CH2 . TRP D 1 178 ? 100.149 38.585 -14.433 1.00 67.13 ? 178 TRP D CH2 1 ATOM 4606 N N . GLU D 1 179 ? 101.142 34.341 -15.652 1.00 68.81 ? 179 GLU D N 1 ATOM 4607 C CA . GLU D 1 179 ? 101.143 35.143 -16.865 1.00 71.75 ? 179 GLU D CA 1 ATOM 4608 C C . GLU D 1 179 ? 99.770 35.739 -17.140 1.00 77.54 ? 179 GLU D C 1 ATOM 4609 O O . GLU D 1 179 ? 98.763 35.030 -17.145 1.00 79.45 ? 179 GLU D O 1 ATOM 4610 C CB . GLU D 1 179 ? 101.615 34.316 -18.060 1.00 64.84 ? 179 GLU D CB 1 ATOM 4611 C CG . GLU D 1 179 ? 100.728 33.167 -18.436 1.00 58.22 ? 179 GLU D CG 1 ATOM 4612 C CD . GLU D 1 179 ? 101.221 32.472 -19.684 1.00 58.00 ? 179 GLU D CD 1 ATOM 4613 O OE1 . GLU D 1 179 ? 102.337 31.919 -19.647 1.00 62.53 ? 179 GLU D OE1 1 ATOM 4614 O OE2 . GLU D 1 179 ? 100.505 32.483 -20.705 1.00 54.39 ? 179 GLU D OE2 1 ATOM 4615 N N . PHE D 1 180 ? 99.732 37.052 -17.354 1.00 82.07 ? 180 PHE D N 1 ATOM 4616 C CA . PHE D 1 180 ? 98.479 37.737 -17.626 1.00 85.66 ? 180 PHE D CA 1 ATOM 4617 C C . PHE D 1 180 ? 97.738 37.057 -18.759 1.00 88.29 ? 180 PHE D C 1 ATOM 4618 O O . PHE D 1 180 ? 98.347 36.539 -19.697 1.00 86.89 ? 180 PHE D O 1 ATOM 4619 C CB . PHE D 1 180 ? 98.733 39.201 -17.976 1.00 88.12 ? 180 PHE D CB 1 ATOM 4620 C CG . PHE D 1 180 ? 97.533 39.909 -18.547 1.00 91.54 ? 180 PHE D CG 1 ATOM 4621 C CD1 . PHE D 1 180 ? 97.187 39.755 -19.890 1.00 92.87 ? 180 PHE D CD1 1 ATOM 4622 C CD2 . PHE D 1 180 ? 96.739 40.720 -17.742 1.00 93.71 ? 180 PHE D CD2 1 ATOM 4623 C CE1 . PHE D 1 180 ? 96.070 40.395 -20.423 1.00 93.78 ? 180 PHE D CE1 1 ATOM 4624 C CE2 . PHE D 1 180 ? 95.618 41.366 -18.265 1.00 96.00 ? 180 PHE D CE2 1 ATOM 4625 C CZ . PHE D 1 180 ? 95.283 41.203 -19.609 1.00 95.19 ? 180 PHE D CZ 1 ATOM 4626 N N . ASP D 1 181 ? 96.413 37.082 -18.667 1.00 92.96 ? 181 ASP D N 1 ATOM 4627 C CA . ASP D 1 181 ? 95.558 36.460 -19.665 1.00 97.59 ? 181 ASP D CA 1 ATOM 4628 C C . ASP D 1 181 ? 95.958 34.995 -19.701 1.00 100.81 ? 181 ASP D C 1 ATOM 4629 O O . ASP D 1 181 ? 96.502 34.512 -20.696 1.00 101.24 ? 181 ASP D O 1 ATOM 4630 C CB . ASP D 1 181 ? 95.770 37.104 -21.042 1.00 96.18 ? 181 ASP D CB 1 ATOM 4631 C CG . ASP D 1 181 ? 94.589 36.894 -21.972 1.00 95.00 ? 181 ASP D CG 1 ATOM 4632 O OD1 . ASP D 1 181 ? 94.658 37.340 -23.136 1.00 93.44 ? 181 ASP D OD1 1 ATOM 4633 O OD2 . ASP D 1 181 ? 93.589 36.286 -21.535 1.00 96.49 ? 181 ASP D OD2 1 ATOM 4634 N N . ALA D 1 182 ? 95.707 34.307 -18.589 1.00 104.41 ? 182 ALA D N 1 ATOM 4635 C CA . ALA D 1 182 ? 96.029 32.889 -18.447 1.00 108.23 ? 182 ALA D CA 1 ATOM 4636 C C . ALA D 1 182 ? 95.653 32.388 -17.055 1.00 110.21 ? 182 ALA D C 1 ATOM 4637 O O . ALA D 1 182 ? 94.863 31.422 -16.973 1.00 111.97 ? 182 ALA D O 1 ATOM 4638 C CB . ALA D 1 182 ? 97.514 32.658 -18.693 1.00 108.72 ? 182 ALA D CB 1 ATOM 4639 O OXT . ALA D 1 182 ? 96.160 32.964 -16.066 1.00 112.05 ? 182 ALA D OXT 1 ATOM 4640 N N . ASP E 2 2 ? 121.401 17.423 -0.543 1.00 113.78 ? 2 ASP E N 1 ATOM 4641 C CA . ASP E 2 2 ? 121.834 17.509 0.883 1.00 113.21 ? 2 ASP E CA 1 ATOM 4642 C C . ASP E 2 2 ? 120.974 16.576 1.737 1.00 112.63 ? 2 ASP E C 1 ATOM 4643 O O . ASP E 2 2 ? 119.832 16.274 1.383 1.00 112.48 ? 2 ASP E O 1 ATOM 4644 C CB . ASP E 2 2 ? 121.697 18.952 1.384 1.00 113.44 ? 2 ASP E CB 1 ATOM 4645 C CG . ASP E 2 2 ? 122.428 19.192 2.696 1.00 112.77 ? 2 ASP E CG 1 ATOM 4646 O OD1 . ASP E 2 2 ? 122.272 20.293 3.268 1.00 113.08 ? 2 ASP E OD1 1 ATOM 4647 O OD2 . ASP E 2 2 ? 123.162 18.289 3.151 1.00 112.37 ? 2 ASP E OD2 1 ATOM 4648 N N . THR E 2 3 ? 121.530 16.126 2.859 1.00 111.67 ? 3 THR E N 1 ATOM 4649 C CA . THR E 2 3 ? 120.826 15.224 3.769 1.00 109.07 ? 3 THR E CA 1 ATOM 4650 C C . THR E 2 3 ? 120.912 15.718 5.218 1.00 107.14 ? 3 THR E C 1 ATOM 4651 O O . THR E 2 3 ? 119.938 16.233 5.767 1.00 107.93 ? 3 THR E O 1 ATOM 4652 C CB . THR E 2 3 ? 121.415 13.802 3.684 1.00 108.99 ? 3 THR E CB 1 ATOM 4653 O OG1 . THR E 2 3 ? 122.798 13.834 4.060 1.00 108.68 ? 3 THR E OG1 1 ATOM 4654 C CG2 . THR E 2 3 ? 121.294 13.260 2.261 1.00 108.05 ? 3 THR E CG2 1 ATOM 4655 N N . ARG E 2 4 ? 122.085 15.539 5.820 1.00 104.18 ? 4 ARG E N 1 ATOM 4656 C CA . ARG E 2 4 ? 122.389 15.960 7.191 1.00 102.10 ? 4 ARG E CA 1 ATOM 4657 C C . ARG E 2 4 ? 121.177 16.344 8.058 1.00 99.33 ? 4 ARG E C 1 ATOM 4658 O O . ARG E 2 4 ? 120.651 17.451 7.957 1.00 101.03 ? 4 ARG E O 1 ATOM 4659 C CB . ARG E 2 4 ? 123.396 17.114 7.129 1.00 103.35 ? 4 ARG E CB 1 ATOM 4660 C CG . ARG E 2 4 ? 124.214 17.098 5.834 1.00 103.75 ? 4 ARG E CG 1 ATOM 4661 C CD . ARG E 2 4 ? 125.495 17.915 5.891 1.00 104.89 ? 4 ARG E CD 1 ATOM 4662 N NE . ARG E 2 4 ? 125.281 19.330 6.177 1.00 106.58 ? 4 ARG E NE 1 ATOM 4663 C CZ . ARG E 2 4 ? 125.134 19.837 7.398 1.00 108.48 ? 4 ARG E CZ 1 ATOM 4664 N NH1 . ARG E 2 4 ? 125.175 19.044 8.463 1.00 107.77 ? 4 ARG E NH1 1 ATOM 4665 N NH2 . ARG E 2 4 ? 124.963 21.144 7.555 1.00 109.38 ? 4 ARG E NH2 1 ATOM 4666 N N . PRO E 2 5 ? 120.739 15.426 8.938 1.00 96.04 ? 5 PRO E N 1 ATOM 4667 C CA . PRO E 2 5 ? 119.610 15.534 9.871 1.00 93.64 ? 5 PRO E CA 1 ATOM 4668 C C . PRO E 2 5 ? 119.405 16.866 10.584 1.00 91.10 ? 5 PRO E C 1 ATOM 4669 O O . PRO E 2 5 ? 120.087 17.168 11.563 1.00 91.76 ? 5 PRO E O 1 ATOM 4670 C CB . PRO E 2 5 ? 119.880 14.407 10.857 1.00 93.58 ? 5 PRO E CB 1 ATOM 4671 C CG . PRO E 2 5 ? 120.455 13.363 9.980 1.00 95.17 ? 5 PRO E CG 1 ATOM 4672 C CD . PRO E 2 5 ? 121.445 14.150 9.148 1.00 95.12 ? 5 PRO E CD 1 ATOM 4673 N N . ARG E 2 6 ? 118.442 17.646 10.106 1.00 86.71 ? 6 ARG E N 1 ATOM 4674 C CA . ARG E 2 6 ? 118.144 18.933 10.710 1.00 82.28 ? 6 ARG E CA 1 ATOM 4675 C C . ARG E 2 6 ? 117.405 18.792 12.035 1.00 80.24 ? 6 ARG E C 1 ATOM 4676 O O . ARG E 2 6 ? 116.461 18.017 12.141 1.00 82.48 ? 6 ARG E O 1 ATOM 4677 C CB . ARG E 2 6 ? 117.319 19.779 9.746 1.00 81.13 ? 6 ARG E CB 1 ATOM 4678 C CG . ARG E 2 6 ? 118.144 20.786 8.982 1.00 81.41 ? 6 ARG E CG 1 ATOM 4679 C CD . ARG E 2 6 ? 119.161 20.119 8.086 1.00 82.02 ? 6 ARG E CD 1 ATOM 4680 N NE . ARG E 2 6 ? 120.139 21.081 7.588 1.00 81.47 ? 6 ARG E NE 1 ATOM 4681 C CZ . ARG E 2 6 ? 120.872 20.904 6.493 1.00 81.68 ? 6 ARG E CZ 1 ATOM 4682 N NH1 . ARG E 2 6 ? 120.739 19.797 5.773 1.00 81.26 ? 6 ARG E NH1 1 ATOM 4683 N NH2 . ARG E 2 6 ? 121.732 21.837 6.109 1.00 80.21 ? 6 ARG E NH2 1 ATOM 4684 N N . PHE E 2 7 ? 117.848 19.534 13.046 1.00 77.19 ? 7 PHE E N 1 ATOM 4685 C CA . PHE E 2 7 ? 117.212 19.509 14.359 1.00 75.26 ? 7 PHE E CA 1 ATOM 4686 C C . PHE E 2 7 ? 116.707 20.903 14.638 1.00 73.66 ? 7 PHE E C 1 ATOM 4687 O O . PHE E 2 7 ? 117.416 21.881 14.408 1.00 74.39 ? 7 PHE E O 1 ATOM 4688 C CB . PHE E 2 7 ? 118.199 19.069 15.432 1.00 77.82 ? 7 PHE E CB 1 ATOM 4689 C CG . PHE E 2 7 ? 118.823 17.744 15.143 1.00 82.71 ? 7 PHE E CG 1 ATOM 4690 C CD1 . PHE E 2 7 ? 118.044 16.692 14.669 1.00 83.51 ? 7 PHE E CD1 1 ATOM 4691 C CD2 . PHE E 2 7 ? 120.187 17.549 15.307 1.00 85.82 ? 7 PHE E CD2 1 ATOM 4692 C CE1 . PHE E 2 7 ? 118.613 15.467 14.359 1.00 84.38 ? 7 PHE E CE1 1 ATOM 4693 C CE2 . PHE E 2 7 ? 120.767 16.325 15.001 1.00 86.77 ? 7 PHE E CE2 1 ATOM 4694 C CZ . PHE E 2 7 ? 119.975 15.281 14.523 1.00 86.28 ? 7 PHE E CZ 1 ATOM 4695 N N . LEU E 2 8 ? 115.483 20.992 15.144 1.00 71.46 ? 8 LEU E N 1 ATOM 4696 C CA . LEU E 2 8 ? 114.863 22.284 15.382 1.00 68.03 ? 8 LEU E CA 1 ATOM 4697 C C . LEU E 2 8 ? 114.294 22.506 16.770 1.00 67.73 ? 8 LEU E C 1 ATOM 4698 O O . LEU E 2 8 ? 113.603 21.650 17.318 1.00 69.23 ? 8 LEU E O 1 ATOM 4699 C CB . LEU E 2 8 ? 113.747 22.481 14.359 1.00 64.03 ? 8 LEU E CB 1 ATOM 4700 C CG . LEU E 2 8 ? 113.243 23.893 14.102 1.00 62.06 ? 8 LEU E CG 1 ATOM 4701 C CD1 . LEU E 2 8 ? 114.382 24.727 13.559 1.00 61.39 ? 8 LEU E CD1 1 ATOM 4702 C CD2 . LEU E 2 8 ? 112.100 23.852 13.100 1.00 61.73 ? 8 LEU E CD2 1 ATOM 4703 N N . GLN E 2 9 ? 114.593 23.669 17.334 1.00 67.16 ? 9 GLN E N 1 ATOM 4704 C CA . GLN E 2 9 ? 114.068 24.041 18.638 1.00 67.53 ? 9 GLN E CA 1 ATOM 4705 C C . GLN E 2 9 ? 113.151 25.213 18.330 1.00 67.38 ? 9 GLN E C 1 ATOM 4706 O O . GLN E 2 9 ? 113.526 26.131 17.602 1.00 70.20 ? 9 GLN E O 1 ATOM 4707 C CB . GLN E 2 9 ? 115.191 24.478 19.575 1.00 68.75 ? 9 GLN E CB 1 ATOM 4708 C CG . GLN E 2 9 ? 115.227 23.717 20.903 1.00 73.68 ? 9 GLN E CG 1 ATOM 4709 C CD . GLN E 2 9 ? 114.225 24.225 21.939 1.00 76.82 ? 9 GLN E CD 1 ATOM 4710 O OE1 . GLN E 2 9 ? 114.356 25.336 22.463 1.00 77.69 ? 9 GLN E OE1 1 ATOM 4711 N NE2 . GLN E 2 9 ? 113.225 23.404 22.245 1.00 75.87 ? 9 GLN E NE2 1 ATOM 4712 N N . GLN E 2 10 ? 111.942 25.180 18.867 1.00 64.18 ? 10 GLN E N 1 ATOM 4713 C CA . GLN E 2 10 ? 110.991 26.240 18.604 1.00 60.34 ? 10 GLN E CA 1 ATOM 4714 C C . GLN E 2 10 ? 110.357 26.615 19.933 1.00 58.86 ? 10 GLN E C 1 ATOM 4715 O O . GLN E 2 10 ? 109.852 25.747 20.645 1.00 57.48 ? 10 GLN E O 1 ATOM 4716 C CB . GLN E 2 10 ? 109.945 25.723 17.606 1.00 61.06 ? 10 GLN E CB 1 ATOM 4717 C CG . GLN E 2 10 ? 109.233 26.771 16.769 1.00 64.12 ? 10 GLN E CG 1 ATOM 4718 C CD . GLN E 2 10 ? 108.560 26.168 15.538 1.00 66.43 ? 10 GLN E CD 1 ATOM 4719 O OE1 . GLN E 2 10 ? 107.800 26.837 14.829 1.00 67.93 ? 10 GLN E OE1 1 ATOM 4720 N NE2 . GLN E 2 10 ? 108.847 24.899 15.276 1.00 67.21 ? 10 GLN E NE2 1 ATOM 4721 N N . ASP E 2 11 ? 110.425 27.900 20.283 1.00 58.84 ? 11 ASP E N 1 ATOM 4722 C CA . ASP E 2 11 ? 109.834 28.399 21.528 1.00 58.66 ? 11 ASP E CA 1 ATOM 4723 C C . ASP E 2 11 ? 108.752 29.440 21.252 1.00 56.64 ? 11 ASP E C 1 ATOM 4724 O O . ASP E 2 11 ? 108.974 30.415 20.530 1.00 54.97 ? 11 ASP E O 1 ATOM 4725 C CB . ASP E 2 11 ? 110.907 28.990 22.437 1.00 63.32 ? 11 ASP E CB 1 ATOM 4726 C CG . ASP E 2 11 ? 111.323 28.036 23.549 1.00 68.37 ? 11 ASP E CG 1 ATOM 4727 O OD1 . ASP E 2 11 ? 110.467 27.700 24.399 1.00 68.24 ? 11 ASP E OD1 1 ATOM 4728 O OD2 . ASP E 2 11 ? 112.505 27.623 23.576 1.00 71.77 ? 11 ASP E OD2 1 ATOM 4729 N N . LYS E 2 12 ? 107.574 29.221 21.829 1.00 55.29 ? 12 LYS E N 1 ATOM 4730 C CA . LYS E 2 12 ? 106.453 30.121 21.620 1.00 53.31 ? 12 LYS E CA 1 ATOM 4731 C C . LYS E 2 12 ? 105.820 30.585 22.922 1.00 55.61 ? 12 LYS E C 1 ATOM 4732 O O . LYS E 2 12 ? 105.477 29.771 23.796 1.00 50.36 ? 12 LYS E O 1 ATOM 4733 C CB . LYS E 2 12 ? 105.389 29.452 20.734 1.00 48.55 ? 12 LYS E CB 1 ATOM 4734 C CG . LYS E 2 12 ? 105.800 29.303 19.272 1.00 45.14 ? 12 LYS E CG 1 ATOM 4735 C CD . LYS E 2 12 ? 104.744 28.593 18.420 1.00 42.65 ? 12 LYS E CD 1 ATOM 4736 C CE . LYS E 2 12 ? 105.197 28.541 16.959 1.00 38.86 ? 12 LYS E CE 1 ATOM 4737 N NZ . LYS E 2 12 ? 104.281 27.799 16.047 1.00 38.82 ? 12 LYS E NZ 1 ATOM 4738 N N . TYR E 2 13 ? 105.698 31.909 23.037 1.00 58.00 ? 13 TYR E N 1 ATOM 4739 C CA . TYR E 2 13 ? 105.082 32.563 24.189 1.00 59.37 ? 13 TYR E CA 1 ATOM 4740 C C . TYR E 2 13 ? 103.834 33.216 23.633 1.00 60.76 ? 13 TYR E C 1 ATOM 4741 O O . TYR E 2 13 ? 103.918 34.161 22.842 1.00 60.75 ? 13 TYR E O 1 ATOM 4742 C CB . TYR E 2 13 ? 106.015 33.623 24.789 1.00 58.84 ? 13 TYR E CB 1 ATOM 4743 C CG . TYR E 2 13 ? 107.354 33.059 25.190 1.00 57.63 ? 13 TYR E CG 1 ATOM 4744 C CD1 . TYR E 2 13 ? 108.435 33.114 24.318 1.00 56.00 ? 13 TYR E CD1 1 ATOM 4745 C CD2 . TYR E 2 13 ? 107.509 32.368 26.393 1.00 56.80 ? 13 TYR E CD2 1 ATOM 4746 C CE1 . TYR E 2 13 ? 109.636 32.490 24.622 1.00 58.92 ? 13 TYR E CE1 1 ATOM 4747 C CE2 . TYR E 2 13 ? 108.707 31.734 26.709 1.00 58.24 ? 13 TYR E CE2 1 ATOM 4748 C CZ . TYR E 2 13 ? 109.769 31.796 25.814 1.00 62.04 ? 13 TYR E CZ 1 ATOM 4749 O OH . TYR E 2 13 ? 110.960 31.150 26.091 1.00 65.58 ? 13 TYR E OH 1 ATOM 4750 N N . GLU E 2 14 ? 102.678 32.697 24.038 1.00 62.36 ? 14 GLU E N 1 ATOM 4751 C CA . GLU E 2 14 ? 101.406 33.205 23.546 1.00 64.01 ? 14 GLU E CA 1 ATOM 4752 C C . GLU E 2 14 ? 100.553 33.899 24.608 1.00 63.34 ? 14 GLU E C 1 ATOM 4753 O O . GLU E 2 14 ? 100.390 33.405 25.732 1.00 57.38 ? 14 GLU E O 1 ATOM 4754 C CB . GLU E 2 14 ? 100.608 32.057 22.909 1.00 67.72 ? 14 GLU E CB 1 ATOM 4755 C CG . GLU E 2 14 ? 101.403 31.227 21.902 1.00 69.17 ? 14 GLU E CG 1 ATOM 4756 C CD . GLU E 2 14 ? 100.669 29.977 21.450 1.00 70.27 ? 14 GLU E CD 1 ATOM 4757 O OE1 . GLU E 2 14 ? 100.010 29.345 22.304 1.00 70.30 ? 14 GLU E OE1 1 ATOM 4758 O OE2 . GLU E 2 14 ? 100.766 29.619 20.251 1.00 70.27 ? 14 GLU E OE2 1 ATOM 4759 N N . CYS E 2 15 ? 100.022 35.058 24.223 1.00 65.33 ? 15 CYS E N 1 ATOM 4760 C CA . CYS E 2 15 ? 99.152 35.868 25.072 1.00 67.67 ? 15 CYS E CA 1 ATOM 4761 C C . CYS E 2 15 ? 97.805 35.945 24.374 1.00 67.06 ? 15 CYS E C 1 ATOM 4762 O O . CYS E 2 15 ? 97.648 36.627 23.356 1.00 63.78 ? 15 CYS E O 1 ATOM 4763 C CB . CYS E 2 15 ? 99.723 37.276 25.257 1.00 70.44 ? 15 CYS E CB 1 ATOM 4764 S SG . CYS E 2 15 ? 101.119 37.399 26.429 1.00 75.26 ? 15 CYS E SG 1 ATOM 4765 N N . HIS E 2 16 ? 96.839 35.226 24.929 1.00 68.79 ? 16 HIS E N 1 ATOM 4766 C CA . HIS E 2 16 ? 95.505 35.162 24.357 1.00 71.68 ? 16 HIS E CA 1 ATOM 4767 C C . HIS E 2 16 ? 94.541 36.093 25.071 1.00 70.87 ? 16 HIS E C 1 ATOM 4768 O O . HIS E 2 16 ? 94.290 35.945 26.264 1.00 69.44 ? 16 HIS E O 1 ATOM 4769 C CB . HIS E 2 16 ? 95.006 33.707 24.398 1.00 73.19 ? 16 HIS E CB 1 ATOM 4770 C CG . HIS E 2 16 ? 95.837 32.765 23.574 1.00 73.68 ? 16 HIS E CG 1 ATOM 4771 N ND1 . HIS E 2 16 ? 95.748 32.695 22.199 1.00 71.92 ? 16 HIS E ND1 1 ATOM 4772 C CD2 . HIS E 2 16 ? 96.827 31.910 23.928 1.00 73.89 ? 16 HIS E CD2 1 ATOM 4773 C CE1 . HIS E 2 16 ? 96.649 31.843 21.742 1.00 71.32 ? 16 HIS E CE1 1 ATOM 4774 N NE2 . HIS E 2 16 ? 97.318 31.354 22.771 1.00 71.68 ? 16 HIS E NE2 1 ATOM 4775 N N . PHE E 2 17 ? 93.997 37.046 24.321 1.00 70.91 ? 17 PHE E N 1 ATOM 4776 C CA . PHE E 2 17 ? 93.077 38.026 24.868 1.00 72.00 ? 17 PHE E CA 1 ATOM 4777 C C . PHE E 2 17 ? 91.627 37.835 24.447 1.00 75.67 ? 17 PHE E C 1 ATOM 4778 O O . PHE E 2 17 ? 91.323 37.719 23.260 1.00 77.23 ? 17 PHE E O 1 ATOM 4779 C CB . PHE E 2 17 ? 93.527 39.419 24.453 1.00 66.91 ? 17 PHE E CB 1 ATOM 4780 C CG . PHE E 2 17 ? 94.926 39.746 24.861 1.00 63.46 ? 17 PHE E CG 1 ATOM 4781 C CD1 . PHE E 2 17 ? 95.233 40.014 26.188 1.00 63.51 ? 17 PHE E CD1 1 ATOM 4782 C CD2 . PHE E 2 17 ? 95.937 39.804 23.916 1.00 63.08 ? 17 PHE E CD2 1 ATOM 4783 C CE1 . PHE E 2 17 ? 96.528 40.341 26.569 1.00 64.24 ? 17 PHE E CE1 1 ATOM 4784 C CE2 . PHE E 2 17 ? 97.234 40.128 24.281 1.00 64.75 ? 17 PHE E CE2 1 ATOM 4785 C CZ . PHE E 2 17 ? 97.531 40.399 25.611 1.00 66.30 ? 17 PHE E CZ 1 ATOM 4786 N N . PHE E 2 18 ? 90.739 37.808 25.437 1.00 79.79 ? 18 PHE E N 1 ATOM 4787 C CA . PHE E 2 18 ? 89.300 37.681 25.210 1.00 83.04 ? 18 PHE E CA 1 ATOM 4788 C C . PHE E 2 18 ? 88.688 38.942 25.827 1.00 84.63 ? 18 PHE E C 1 ATOM 4789 O O . PHE E 2 18 ? 89.013 39.295 26.964 1.00 84.07 ? 18 PHE E O 1 ATOM 4790 C CB . PHE E 2 18 ? 88.726 36.458 25.931 1.00 83.86 ? 18 PHE E CB 1 ATOM 4791 C CG . PHE E 2 18 ? 89.372 35.159 25.557 1.00 85.04 ? 18 PHE E CG 1 ATOM 4792 C CD1 . PHE E 2 18 ? 90.725 34.946 25.791 1.00 86.11 ? 18 PHE E CD1 1 ATOM 4793 C CD2 . PHE E 2 18 ? 88.611 34.125 25.026 1.00 87.36 ? 18 PHE E CD2 1 ATOM 4794 C CE1 . PHE E 2 18 ? 91.314 33.720 25.507 1.00 88.50 ? 18 PHE E CE1 1 ATOM 4795 C CE2 . PHE E 2 18 ? 89.185 32.892 24.737 1.00 90.41 ? 18 PHE E CE2 1 ATOM 4796 C CZ . PHE E 2 18 ? 90.543 32.687 24.980 1.00 91.39 ? 18 PHE E CZ 1 ATOM 4797 N N . ASN E 2 19 ? 87.802 39.615 25.099 1.00 85.84 ? 19 ASN E N 1 ATOM 4798 C CA . ASN E 2 19 ? 87.194 40.835 25.619 1.00 86.32 ? 19 ASN E CA 1 ATOM 4799 C C . ASN E 2 19 ? 88.329 41.791 25.946 1.00 85.20 ? 19 ASN E C 1 ATOM 4800 O O . ASN E 2 19 ? 88.592 42.053 27.115 1.00 86.30 ? 19 ASN E O 1 ATOM 4801 C CB . ASN E 2 19 ? 86.400 40.554 26.908 1.00 89.08 ? 19 ASN E CB 1 ATOM 4802 C CG . ASN E 2 19 ? 85.046 39.903 26.649 1.00 94.02 ? 19 ASN E CG 1 ATOM 4803 O OD1 . ASN E 2 19 ? 84.959 38.818 26.066 1.00 97.07 ? 19 ASN E OD1 1 ATOM 4804 N ND2 . ASN E 2 19 ? 83.978 40.565 27.094 1.00 94.81 ? 19 ASN E ND2 1 ATOM 4805 N N . GLY E 2 20 ? 89.009 42.306 24.927 1.00 84.37 ? 20 GLY E N 1 ATOM 4806 C CA . GLY E 2 20 ? 90.109 43.215 25.198 1.00 85.83 ? 20 GLY E CA 1 ATOM 4807 C C . GLY E 2 20 ? 91.107 42.533 26.119 1.00 86.15 ? 20 GLY E C 1 ATOM 4808 O O . GLY E 2 20 ? 91.733 41.557 25.710 1.00 89.72 ? 20 GLY E O 1 ATOM 4809 N N . THR E 2 21 ? 91.253 43.019 27.353 1.00 83.55 ? 21 THR E N 1 ATOM 4810 C CA . THR E 2 21 ? 92.189 42.408 28.306 1.00 81.03 ? 21 THR E CA 1 ATOM 4811 C C . THR E 2 21 ? 91.462 41.925 29.560 1.00 79.02 ? 21 THR E C 1 ATOM 4812 O O . THR E 2 21 ? 92.073 41.638 30.586 1.00 73.72 ? 21 THR E O 1 ATOM 4813 C CB . THR E 2 21 ? 93.295 43.396 28.721 1.00 81.33 ? 21 THR E CB 1 ATOM 4814 O OG1 . THR E 2 21 ? 92.739 44.401 29.570 1.00 84.96 ? 21 THR E OG1 1 ATOM 4815 C CG2 . THR E 2 21 ? 93.904 44.066 27.493 1.00 78.36 ? 21 THR E CG2 1 ATOM 4816 N N . GLU E 2 22 ? 90.145 41.833 29.444 1.00 81.55 ? 22 GLU E N 1 ATOM 4817 C CA . GLU E 2 22 ? 89.260 41.393 30.518 1.00 85.83 ? 22 GLU E CA 1 ATOM 4818 C C . GLU E 2 22 ? 89.535 39.965 30.980 1.00 85.33 ? 22 GLU E C 1 ATOM 4819 O O . GLU E 2 22 ? 89.219 39.596 32.113 1.00 85.01 ? 22 GLU E O 1 ATOM 4820 C CB . GLU E 2 22 ? 87.814 41.508 30.030 1.00 90.88 ? 22 GLU E CB 1 ATOM 4821 C CG . GLU E 2 22 ? 86.769 40.823 30.881 1.00 98.50 ? 22 GLU E CG 1 ATOM 4822 C CD . GLU E 2 22 ? 85.391 40.900 30.243 1.00 104.28 ? 22 GLU E CD 1 ATOM 4823 O OE1 . GLU E 2 22 ? 84.899 42.032 30.021 1.00 106.73 ? 22 GLU E OE1 1 ATOM 4824 O OE2 . GLU E 2 22 ? 84.806 39.830 29.959 1.00 107.31 ? 22 GLU E OE2 1 ATOM 4825 N N . ARG E 2 23 ? 90.117 39.166 30.094 1.00 85.15 ? 23 ARG E N 1 ATOM 4826 C CA . ARG E 2 23 ? 90.430 37.774 30.392 1.00 83.83 ? 23 ARG E CA 1 ATOM 4827 C C . ARG E 2 23 ? 91.605 37.382 29.505 1.00 80.75 ? 23 ARG E C 1 ATOM 4828 O O . ARG E 2 23 ? 91.432 37.089 28.324 1.00 80.10 ? 23 ARG E O 1 ATOM 4829 C CB . ARG E 2 23 ? 89.212 36.899 30.080 1.00 88.48 ? 23 ARG E CB 1 ATOM 4830 C CG . ARG E 2 23 ? 89.159 35.556 30.799 1.00 94.92 ? 23 ARG E CG 1 ATOM 4831 C CD . ARG E 2 23 ? 90.342 34.663 30.466 1.00 102.02 ? 23 ARG E CD 1 ATOM 4832 N NE . ARG E 2 23 ? 90.084 33.265 30.812 1.00 108.27 ? 23 ARG E NE 1 ATOM 4833 C CZ . ARG E 2 23 ? 90.997 32.296 30.763 1.00 112.20 ? 23 ARG E CZ 1 ATOM 4834 N NH1 . ARG E 2 23 ? 92.241 32.564 30.385 1.00 114.07 ? 23 ARG E NH1 1 ATOM 4835 N NH2 . ARG E 2 23 ? 90.664 31.052 31.079 1.00 113.68 ? 23 ARG E NH2 1 ATOM 4836 N N . VAL E 2 24 ? 92.802 37.386 30.080 1.00 78.24 ? 24 VAL E N 1 ATOM 4837 C CA . VAL E 2 24 ? 94.016 37.056 29.338 1.00 74.94 ? 24 VAL E CA 1 ATOM 4838 C C . VAL E 2 24 ? 94.548 35.673 29.693 1.00 73.77 ? 24 VAL E C 1 ATOM 4839 O O . VAL E 2 24 ? 94.372 35.195 30.815 1.00 73.05 ? 24 VAL E O 1 ATOM 4840 C CB . VAL E 2 24 ? 95.131 38.110 29.609 1.00 73.57 ? 24 VAL E CB 1 ATOM 4841 C CG1 . VAL E 2 24 ? 96.400 37.768 28.839 1.00 70.05 ? 24 VAL E CG1 1 ATOM 4842 C CG2 . VAL E 2 24 ? 94.635 39.493 29.219 1.00 73.83 ? 24 VAL E CG2 1 ATOM 4843 N N . ARG E 2 25 ? 95.187 35.032 28.719 1.00 73.24 ? 25 ARG E N 1 ATOM 4844 C CA . ARG E 2 25 ? 95.771 33.713 28.917 1.00 70.70 ? 25 ARG E CA 1 ATOM 4845 C C . ARG E 2 25 ? 97.200 33.699 28.383 1.00 69.27 ? 25 ARG E C 1 ATOM 4846 O O . ARG E 2 25 ? 97.490 34.234 27.308 1.00 66.22 ? 25 ARG E O 1 ATOM 4847 C CB . ARG E 2 25 ? 94.955 32.646 28.205 1.00 71.74 ? 25 ARG E CB 1 ATOM 4848 C CG . ARG E 2 25 ? 95.287 31.253 28.672 1.00 72.08 ? 25 ARG E CG 1 ATOM 4849 C CD . ARG E 2 25 ? 94.629 30.231 27.791 1.00 75.38 ? 25 ARG E CD 1 ATOM 4850 N NE . ARG E 2 25 ? 94.743 28.888 28.343 1.00 79.38 ? 25 ARG E NE 1 ATOM 4851 C CZ . ARG E 2 25 ? 94.470 27.784 27.659 1.00 80.92 ? 25 ARG E CZ 1 ATOM 4852 N NH1 . ARG E 2 25 ? 94.074 27.875 26.396 1.00 82.80 ? 25 ARG E NH1 1 ATOM 4853 N NH2 . ARG E 2 25 ? 94.577 26.595 28.239 1.00 78.79 ? 25 ARG E NH2 1 ATOM 4854 N N . PHE E 2 26 ? 98.088 33.072 29.143 1.00 67.83 ? 26 PHE E N 1 ATOM 4855 C CA . PHE E 2 26 ? 99.493 33.002 28.779 1.00 67.15 ? 26 PHE E CA 1 ATOM 4856 C C . PHE E 2 26 ? 99.955 31.565 28.585 1.00 67.60 ? 26 PHE E C 1 ATOM 4857 O O . PHE E 2 26 ? 99.620 30.682 29.382 1.00 65.93 ? 26 PHE E O 1 ATOM 4858 C CB . PHE E 2 26 ? 100.324 33.658 29.876 1.00 66.39 ? 26 PHE E CB 1 ATOM 4859 C CG . PHE E 2 26 ? 101.798 33.479 29.707 1.00 64.18 ? 26 PHE E CG 1 ATOM 4860 C CD1 . PHE E 2 26 ? 102.495 34.204 28.738 1.00 62.99 ? 26 PHE E CD1 1 ATOM 4861 C CD2 . PHE E 2 26 ? 102.490 32.574 30.510 1.00 59.15 ? 26 PHE E CD2 1 ATOM 4862 C CE1 . PHE E 2 26 ? 103.866 34.033 28.570 1.00 61.77 ? 26 PHE E CE1 1 ATOM 4863 C CE2 . PHE E 2 26 ? 103.853 32.395 30.353 1.00 58.35 ? 26 PHE E CE2 1 ATOM 4864 C CZ . PHE E 2 26 ? 104.548 33.126 29.379 1.00 60.53 ? 26 PHE E CZ 1 ATOM 4865 N N . LEU E 2 27 ? 100.737 31.342 27.529 1.00 66.66 ? 27 LEU E N 1 ATOM 4866 C CA . LEU E 2 27 ? 101.250 30.011 27.225 1.00 64.25 ? 27 LEU E CA 1 ATOM 4867 C C . LEU E 2 27 ? 102.712 30.000 26.815 1.00 61.94 ? 27 LEU E C 1 ATOM 4868 O O . LEU E 2 27 ? 103.197 30.914 26.147 1.00 57.82 ? 27 LEU E O 1 ATOM 4869 C CB . LEU E 2 27 ? 100.456 29.352 26.078 1.00 65.17 ? 27 LEU E CB 1 ATOM 4870 C CG . LEU E 2 27 ? 99.060 28.730 26.214 1.00 61.98 ? 27 LEU E CG 1 ATOM 4871 C CD1 . LEU E 2 27 ? 99.021 27.841 27.448 1.00 59.75 ? 27 LEU E CD1 1 ATOM 4872 C CD2 . LEU E 2 27 ? 98.005 29.817 26.290 1.00 61.89 ? 27 LEU E CD2 1 ATOM 4873 N N . HIS E 2 28 ? 103.403 28.944 27.227 1.00 62.78 ? 28 HIS E N 1 ATOM 4874 C CA . HIS E 2 28 ? 104.790 28.739 26.843 1.00 65.30 ? 28 HIS E CA 1 ATOM 4875 C C . HIS E 2 28 ? 104.841 27.359 26.213 1.00 63.86 ? 28 HIS E C 1 ATOM 4876 O O . HIS E 2 28 ? 104.503 26.359 26.851 1.00 60.98 ? 28 HIS E O 1 ATOM 4877 C CB . HIS E 2 28 ? 105.749 28.747 28.033 1.00 68.47 ? 28 HIS E CB 1 ATOM 4878 C CG . HIS E 2 28 ? 107.181 28.537 27.636 1.00 70.03 ? 28 HIS E CG 1 ATOM 4879 N ND1 . HIS E 2 28 ? 108.165 28.183 28.535 1.00 70.70 ? 28 HIS E ND1 1 ATOM 4880 C CD2 . HIS E 2 28 ? 107.793 28.638 26.429 1.00 68.92 ? 28 HIS E CD2 1 ATOM 4881 C CE1 . HIS E 2 28 ? 109.319 28.075 27.899 1.00 72.74 ? 28 HIS E CE1 1 ATOM 4882 N NE2 . HIS E 2 28 ? 109.121 28.346 26.621 1.00 69.51 ? 28 HIS E NE2 1 ATOM 4883 N N . ARG E 2 29 ? 105.259 27.304 24.959 1.00 61.75 ? 29 ARG E N 1 ATOM 4884 C CA . ARG E 2 29 ? 105.347 26.034 24.277 1.00 61.41 ? 29 ARG E CA 1 ATOM 4885 C C . ARG E 2 29 ? 106.788 25.769 23.909 1.00 63.15 ? 29 ARG E C 1 ATOM 4886 O O . ARG E 2 29 ? 107.377 26.530 23.149 1.00 64.58 ? 29 ARG E O 1 ATOM 4887 C CB . ARG E 2 29 ? 104.525 26.066 22.996 1.00 62.25 ? 29 ARG E CB 1 ATOM 4888 C CG . ARG E 2 29 ? 103.038 26.295 23.171 1.00 64.54 ? 29 ARG E CG 1 ATOM 4889 C CD . ARG E 2 29 ? 102.409 26.662 21.823 1.00 64.88 ? 29 ARG E CD 1 ATOM 4890 N NE . ARG E 2 29 ? 100.960 26.788 21.900 1.00 63.64 ? 29 ARG E NE 1 ATOM 4891 C CZ . ARG E 2 29 ? 100.134 25.764 22.067 1.00 64.78 ? 29 ARG E CZ 1 ATOM 4892 N NH1 . ARG E 2 29 ? 100.613 24.534 22.170 1.00 66.17 ? 29 ARG E NH1 1 ATOM 4893 N NH2 . ARG E 2 29 ? 98.829 25.971 22.139 1.00 66.84 ? 29 ARG E NH2 1 ATOM 4894 N N . ASP E 2 30 ? 107.373 24.717 24.466 1.00 64.94 ? 30 ASP E N 1 ATOM 4895 C CA . ASP E 2 30 ? 108.738 24.364 24.100 1.00 67.79 ? 30 ASP E CA 1 ATOM 4896 C C . ASP E 2 30 ? 108.505 23.327 23.015 1.00 66.22 ? 30 ASP E C 1 ATOM 4897 O O . ASP E 2 30 ? 107.769 22.360 23.221 1.00 67.12 ? 30 ASP E O 1 ATOM 4898 C CB . ASP E 2 30 ? 109.504 23.741 25.278 1.00 73.05 ? 30 ASP E CB 1 ATOM 4899 C CG . ASP E 2 30 ? 110.998 23.550 24.977 1.00 77.91 ? 30 ASP E CG 1 ATOM 4900 O OD1 . ASP E 2 30 ? 111.360 22.616 24.224 1.00 78.05 ? 30 ASP E OD1 1 ATOM 4901 O OD2 . ASP E 2 30 ? 111.813 24.349 25.489 1.00 81.61 ? 30 ASP E OD2 1 ATOM 4902 N N . ILE E 2 31 ? 109.108 23.522 21.854 1.00 62.49 ? 31 ILE E N 1 ATOM 4903 C CA . ILE E 2 31 ? 108.896 22.578 20.782 1.00 60.33 ? 31 ILE E CA 1 ATOM 4904 C C . ILE E 2 31 ? 110.172 22.004 20.184 1.00 62.90 ? 31 ILE E C 1 ATOM 4905 O O . ILE E 2 31 ? 111.161 22.711 19.972 1.00 62.58 ? 31 ILE E O 1 ATOM 4906 C CB . ILE E 2 31 ? 108.082 23.234 19.681 1.00 57.87 ? 31 ILE E CB 1 ATOM 4907 C CG1 . ILE E 2 31 ? 106.750 23.694 20.248 1.00 56.45 ? 31 ILE E CG1 1 ATOM 4908 C CG2 . ILE E 2 31 ? 107.871 22.275 18.539 1.00 59.33 ? 31 ILE E CG2 1 ATOM 4909 C CD1 . ILE E 2 31 ? 105.996 24.580 19.302 1.00 61.09 ? 31 ILE E CD1 1 ATOM 4910 N N . TYR E 2 32 ? 110.148 20.704 19.928 1.00 64.36 ? 32 TYR E N 1 ATOM 4911 C CA . TYR E 2 32 ? 111.284 20.055 19.315 1.00 67.56 ? 32 TYR E CA 1 ATOM 4912 C C . TYR E 2 32 ? 110.844 19.577 17.943 1.00 68.19 ? 32 TYR E C 1 ATOM 4913 O O . TYR E 2 32 ? 109.811 18.918 17.804 1.00 67.49 ? 32 TYR E O 1 ATOM 4914 C CB . TYR E 2 32 ? 111.777 18.876 20.148 1.00 72.89 ? 32 TYR E CB 1 ATOM 4915 C CG . TYR E 2 32 ? 112.964 18.206 19.506 1.00 77.33 ? 32 TYR E CG 1 ATOM 4916 C CD1 . TYR E 2 32 ? 113.982 18.966 18.932 1.00 79.25 ? 32 TYR E CD1 1 ATOM 4917 C CD2 . TYR E 2 32 ? 113.073 16.823 19.461 1.00 79.39 ? 32 TYR E CD2 1 ATOM 4918 C CE1 . TYR E 2 32 ? 115.077 18.367 18.327 1.00 81.26 ? 32 TYR E CE1 1 ATOM 4919 C CE2 . TYR E 2 32 ? 114.170 16.210 18.860 1.00 81.60 ? 32 TYR E CE2 1 ATOM 4920 C CZ . TYR E 2 32 ? 115.167 16.988 18.295 1.00 82.14 ? 32 TYR E CZ 1 ATOM 4921 O OH . TYR E 2 32 ? 116.253 16.390 17.700 1.00 83.68 ? 32 TYR E OH 1 ATOM 4922 N N . ASN E 2 33 ? 111.634 19.925 16.933 1.00 69.37 ? 33 ASN E N 1 ATOM 4923 C CA . ASN E 2 33 ? 111.341 19.569 15.550 1.00 69.80 ? 33 ASN E CA 1 ATOM 4924 C C . ASN E 2 33 ? 109.925 19.963 15.144 1.00 68.37 ? 33 ASN E C 1 ATOM 4925 O O . ASN E 2 33 ? 109.721 21.012 14.533 1.00 67.11 ? 33 ASN E O 1 ATOM 4926 C CB . ASN E 2 33 ? 111.541 18.069 15.317 1.00 72.62 ? 33 ASN E CB 1 ATOM 4927 C CG . ASN E 2 33 ? 112.992 17.658 15.391 1.00 74.15 ? 33 ASN E CG 1 ATOM 4928 O OD1 . ASN E 2 33 ? 113.847 18.250 14.737 1.00 77.07 ? 33 ASN E OD1 1 ATOM 4929 N ND2 . ASN E 2 33 ? 113.278 16.634 16.180 1.00 73.70 ? 33 ASN E ND2 1 ATOM 4930 N N . GLN E 2 34 ? 108.947 19.128 15.487 1.00 67.96 ? 34 GLN E N 1 ATOM 4931 C CA . GLN E 2 34 ? 107.566 19.406 15.122 1.00 68.02 ? 34 GLN E CA 1 ATOM 4932 C C . GLN E 2 34 ? 106.568 18.949 16.173 1.00 66.63 ? 34 GLN E C 1 ATOM 4933 O O . GLN E 2 34 ? 105.369 18.892 15.913 1.00 66.23 ? 34 GLN E O 1 ATOM 4934 C CB . GLN E 2 34 ? 107.240 18.744 13.779 1.00 71.21 ? 34 GLN E CB 1 ATOM 4935 C CG . GLN E 2 34 ? 105.892 19.135 13.188 1.00 76.31 ? 34 GLN E CG 1 ATOM 4936 C CD . GLN E 2 34 ? 105.657 18.535 11.808 1.00 82.23 ? 34 GLN E CD 1 ATOM 4937 O OE1 . GLN E 2 34 ? 104.601 18.747 11.196 1.00 84.00 ? 34 GLN E OE1 1 ATOM 4938 N NE2 . GLN E 2 34 ? 106.642 17.783 11.307 1.00 82.26 ? 34 GLN E NE2 1 ATOM 4939 N N . GLU E 2 35 ? 107.052 18.627 17.364 1.00 66.54 ? 35 GLU E N 1 ATOM 4940 C CA . GLU E 2 35 ? 106.151 18.192 18.419 1.00 70.36 ? 35 GLU E CA 1 ATOM 4941 C C . GLU E 2 35 ? 106.309 19.019 19.692 1.00 69.74 ? 35 GLU E C 1 ATOM 4942 O O . GLU E 2 35 ? 107.427 19.340 20.097 1.00 69.23 ? 35 GLU E O 1 ATOM 4943 C CB . GLU E 2 35 ? 106.380 16.706 18.740 1.00 76.23 ? 35 GLU E CB 1 ATOM 4944 C CG . GLU E 2 35 ? 107.782 16.369 19.263 1.00 79.31 ? 35 GLU E CG 1 ATOM 4945 C CD . GLU E 2 35 ? 107.866 14.996 19.926 1.00 78.23 ? 35 GLU E CD 1 ATOM 4946 O OE1 . GLU E 2 35 ? 107.539 13.982 19.273 1.00 77.20 ? 35 GLU E OE1 1 ATOM 4947 O OE2 . GLU E 2 35 ? 108.265 14.936 21.107 1.00 78.99 ? 35 GLU E OE2 1 ATOM 4948 N N . GLU E 2 36 ? 105.184 19.362 20.316 1.00 70.58 ? 36 GLU E N 1 ATOM 4949 C CA . GLU E 2 36 ? 105.201 20.130 21.560 1.00 73.76 ? 36 GLU E CA 1 ATOM 4950 C C . GLU E 2 36 ? 105.441 19.172 22.725 1.00 73.73 ? 36 GLU E C 1 ATOM 4951 O O . GLU E 2 36 ? 104.646 18.258 22.956 1.00 73.63 ? 36 GLU E O 1 ATOM 4952 C CB . GLU E 2 36 ? 103.867 20.858 21.771 1.00 75.18 ? 36 GLU E CB 1 ATOM 4953 C CG . GLU E 2 36 ? 103.760 21.566 23.124 1.00 75.02 ? 36 GLU E CG 1 ATOM 4954 C CD . GLU E 2 36 ? 102.387 22.173 23.372 1.00 75.95 ? 36 GLU E CD 1 ATOM 4955 O OE1 . GLU E 2 36 ? 101.393 21.422 23.358 1.00 73.97 ? 36 GLU E OE1 1 ATOM 4956 O OE2 . GLU E 2 36 ? 102.299 23.400 23.585 1.00 78.02 ? 36 GLU E OE2 1 ATOM 4957 N N . ASP E 2 37 ? 106.527 19.396 23.462 1.00 72.42 ? 37 ASP E N 1 ATOM 4958 C CA . ASP E 2 37 ? 106.884 18.538 24.585 1.00 71.23 ? 37 ASP E CA 1 ATOM 4959 C C . ASP E 2 37 ? 106.673 19.179 25.945 1.00 68.34 ? 37 ASP E C 1 ATOM 4960 O O . ASP E 2 37 ? 106.240 18.525 26.893 1.00 65.14 ? 37 ASP E O 1 ATOM 4961 C CB . ASP E 2 37 ? 108.346 18.098 24.455 1.00 76.82 ? 37 ASP E CB 1 ATOM 4962 C CG . ASP E 2 37 ? 109.275 19.251 24.114 1.00 79.49 ? 37 ASP E CG 1 ATOM 4963 O OD1 . ASP E 2 37 ? 109.178 19.770 22.983 1.00 82.26 ? 37 ASP E OD1 1 ATOM 4964 O OD2 . ASP E 2 37 ? 110.097 19.639 24.971 1.00 79.42 ? 37 ASP E OD2 1 ATOM 4965 N N . LEU E 2 38 ? 106.997 20.459 26.045 1.00 67.07 ? 38 LEU E N 1 ATOM 4966 C CA . LEU E 2 38 ? 106.842 21.161 27.305 1.00 67.96 ? 38 LEU E CA 1 ATOM 4967 C C . LEU E 2 38 ? 105.868 22.308 27.108 1.00 66.02 ? 38 LEU E C 1 ATOM 4968 O O . LEU E 2 38 ? 105.864 22.944 26.057 1.00 64.38 ? 38 LEU E O 1 ATOM 4969 C CB . LEU E 2 38 ? 108.197 21.683 27.779 1.00 71.80 ? 38 LEU E CB 1 ATOM 4970 C CG . LEU E 2 38 ? 108.238 22.340 29.161 1.00 75.05 ? 38 LEU E CG 1 ATOM 4971 C CD1 . LEU E 2 38 ? 107.659 21.408 30.214 1.00 72.38 ? 38 LEU E CD1 1 ATOM 4972 C CD2 . LEU E 2 38 ? 109.676 22.702 29.491 1.00 78.07 ? 38 LEU E CD2 1 ATOM 4973 N N . ARG E 2 39 ? 105.046 22.579 28.116 1.00 65.73 ? 39 ARG E N 1 ATOM 4974 C CA . ARG E 2 39 ? 104.065 23.646 27.987 1.00 65.93 ? 39 ARG E CA 1 ATOM 4975 C C . ARG E 2 39 ? 103.549 24.246 29.295 1.00 66.01 ? 39 ARG E C 1 ATOM 4976 O O . ARG E 2 39 ? 103.042 23.523 30.160 1.00 64.18 ? 39 ARG E O 1 ATOM 4977 C CB . ARG E 2 39 ? 102.883 23.125 27.168 1.00 67.64 ? 39 ARG E CB 1 ATOM 4978 C CG . ARG E 2 39 ? 101.768 24.127 26.961 1.00 72.07 ? 39 ARG E CG 1 ATOM 4979 C CD . ARG E 2 39 ? 100.447 23.604 27.508 1.00 74.31 ? 39 ARG E CD 1 ATOM 4980 N NE . ARG E 2 39 ? 100.007 22.393 26.824 1.00 75.52 ? 39 ARG E NE 1 ATOM 4981 C CZ . ARG E 2 39 ? 99.724 22.323 25.528 1.00 73.92 ? 39 ARG E CZ 1 ATOM 4982 N NH1 . ARG E 2 39 ? 99.832 23.399 24.757 1.00 68.13 ? 39 ARG E NH1 1 ATOM 4983 N NH2 . ARG E 2 39 ? 99.329 21.171 25.007 1.00 75.59 ? 39 ARG E NH2 1 ATOM 4984 N N . PHE E 2 40 ? 103.684 25.568 29.436 1.00 65.96 ? 40 PHE E N 1 ATOM 4985 C CA . PHE E 2 40 ? 103.177 26.253 30.620 1.00 67.27 ? 40 PHE E CA 1 ATOM 4986 C C . PHE E 2 40 ? 101.881 26.954 30.271 1.00 67.39 ? 40 PHE E C 1 ATOM 4987 O O . PHE E 2 40 ? 101.839 27.786 29.359 1.00 64.43 ? 40 PHE E O 1 ATOM 4988 C CB . PHE E 2 40 ? 104.152 27.297 31.161 1.00 70.93 ? 40 PHE E CB 1 ATOM 4989 C CG . PHE E 2 40 ? 103.569 28.133 32.288 1.00 78.26 ? 40 PHE E CG 1 ATOM 4990 C CD1 . PHE E 2 40 ? 102.679 29.180 32.019 1.00 79.65 ? 40 PHE E CD1 1 ATOM 4991 C CD2 . PHE E 2 40 ? 103.859 27.834 33.621 1.00 80.79 ? 40 PHE E CD2 1 ATOM 4992 C CE1 . PHE E 2 40 ? 102.086 29.912 33.057 1.00 78.32 ? 40 PHE E CE1 1 ATOM 4993 C CE2 . PHE E 2 40 ? 103.270 28.561 34.668 1.00 79.19 ? 40 PHE E CE2 1 ATOM 4994 C CZ . PHE E 2 40 ? 102.383 29.599 34.384 1.00 78.77 ? 40 PHE E CZ 1 ATOM 4995 N N . ASP E 2 41 ? 100.829 26.624 31.011 1.00 68.27 ? 41 ASP E N 1 ATOM 4996 C CA . ASP E 2 41 ? 99.525 27.217 30.781 1.00 71.25 ? 41 ASP E CA 1 ATOM 4997 C C . ASP E 2 41 ? 99.209 28.116 31.964 1.00 72.17 ? 41 ASP E C 1 ATOM 4998 O O . ASP E 2 41 ? 99.290 27.682 33.117 1.00 70.17 ? 41 ASP E O 1 ATOM 4999 C CB . ASP E 2 41 ? 98.462 26.120 30.661 1.00 74.73 ? 41 ASP E CB 1 ATOM 5000 C CG . ASP E 2 41 ? 97.230 26.571 29.880 1.00 77.76 ? 41 ASP E CG 1 ATOM 5001 O OD1 . ASP E 2 41 ? 96.641 27.619 30.217 1.00 79.36 ? 41 ASP E OD1 1 ATOM 5002 O OD2 . ASP E 2 41 ? 96.844 25.865 28.925 1.00 79.91 ? 41 ASP E OD2 1 ATOM 5003 N N . SER E 2 42 ? 98.861 29.369 31.671 1.00 73.65 ? 42 SER E N 1 ATOM 5004 C CA . SER E 2 42 ? 98.524 30.337 32.709 1.00 73.06 ? 42 SER E CA 1 ATOM 5005 C C . SER E 2 42 ? 97.310 29.859 33.501 1.00 71.54 ? 42 SER E C 1 ATOM 5006 O O . SER E 2 42 ? 97.128 30.242 34.653 1.00 70.98 ? 42 SER E O 1 ATOM 5007 C CB . SER E 2 42 ? 98.229 31.703 32.086 1.00 73.54 ? 42 SER E CB 1 ATOM 5008 O OG . SER E 2 42 ? 97.036 31.672 31.322 1.00 75.40 ? 42 SER E OG 1 ATOM 5009 N N . ASP E 2 43 ? 96.489 29.017 32.878 1.00 71.94 ? 43 ASP E N 1 ATOM 5010 C CA . ASP E 2 43 ? 95.294 28.476 33.526 1.00 73.18 ? 43 ASP E CA 1 ATOM 5011 C C . ASP E 2 43 ? 95.561 27.210 34.349 1.00 73.44 ? 43 ASP E C 1 ATOM 5012 O O . ASP E 2 43 ? 94.650 26.681 34.988 1.00 71.67 ? 43 ASP E O 1 ATOM 5013 C CB . ASP E 2 43 ? 94.199 28.170 32.492 1.00 72.52 ? 43 ASP E CB 1 ATOM 5014 C CG . ASP E 2 43 ? 93.664 29.419 31.817 1.00 73.95 ? 43 ASP E CG 1 ATOM 5015 O OD1 . ASP E 2 43 ? 93.917 30.528 32.335 1.00 75.23 ? 43 ASP E OD1 1 ATOM 5016 O OD2 . ASP E 2 43 ? 92.983 29.290 30.774 1.00 72.74 ? 43 ASP E OD2 1 ATOM 5017 N N . VAL E 2 44 ? 96.797 26.718 34.333 1.00 73.80 ? 44 VAL E N 1 ATOM 5018 C CA . VAL E 2 44 ? 97.124 25.517 35.096 1.00 75.18 ? 44 VAL E CA 1 ATOM 5019 C C . VAL E 2 44 ? 98.071 25.850 36.234 1.00 75.70 ? 44 VAL E C 1 ATOM 5020 O O . VAL E 2 44 ? 98.091 25.160 37.258 1.00 76.24 ? 44 VAL E O 1 ATOM 5021 C CB . VAL E 2 44 ? 97.793 24.441 34.224 1.00 76.09 ? 44 VAL E CB 1 ATOM 5022 C CG1 . VAL E 2 44 ? 97.985 23.168 35.038 1.00 74.56 ? 44 VAL E CG1 1 ATOM 5023 C CG2 . VAL E 2 44 ? 96.948 24.166 32.996 1.00 78.63 ? 44 VAL E CG2 1 ATOM 5024 N N . GLY E 2 45 ? 98.865 26.902 36.039 1.00 74.93 ? 45 GLY E N 1 ATOM 5025 C CA . GLY E 2 45 ? 99.806 27.325 37.060 1.00 73.09 ? 45 GLY E CA 1 ATOM 5026 C C . GLY E 2 45 ? 101.213 26.786 36.910 1.00 71.24 ? 45 GLY E C 1 ATOM 5027 O O . GLY E 2 45 ? 102.182 27.531 37.001 1.00 67.84 ? 45 GLY E O 1 ATOM 5028 N N . GLU E 2 46 ? 101.325 25.487 36.670 1.00 73.42 ? 46 GLU E N 1 ATOM 5029 C CA . GLU E 2 46 ? 102.624 24.842 36.528 1.00 75.64 ? 46 GLU E CA 1 ATOM 5030 C C . GLU E 2 46 ? 102.913 24.379 35.105 1.00 75.14 ? 46 GLU E C 1 ATOM 5031 O O . GLU E 2 46 ? 102.118 24.588 34.184 1.00 75.27 ? 46 GLU E O 1 ATOM 5032 C CB . GLU E 2 46 ? 102.684 23.636 37.456 1.00 77.92 ? 46 GLU E CB 1 ATOM 5033 C CG . GLU E 2 46 ? 101.599 22.630 37.148 1.00 85.61 ? 46 GLU E CG 1 ATOM 5034 C CD . GLU E 2 46 ? 101.604 21.459 38.091 1.00 92.60 ? 46 GLU E CD 1 ATOM 5035 O OE1 . GLU E 2 46 ? 101.516 21.691 39.316 1.00 95.82 ? 46 GLU E OE1 1 ATOM 5036 O OE2 . GLU E 2 46 ? 101.691 20.308 37.609 1.00 97.56 ? 46 GLU E OE2 1 ATOM 5037 N N . TYR E 2 47 ? 104.068 23.746 34.939 1.00 75.23 ? 47 TYR E N 1 ATOM 5038 C CA . TYR E 2 47 ? 104.469 23.211 33.648 1.00 76.07 ? 47 TYR E CA 1 ATOM 5039 C C . TYR E 2 47 ? 103.941 21.783 33.516 1.00 77.83 ? 47 TYR E C 1 ATOM 5040 O O . TYR E 2 47 ? 103.771 21.074 34.511 1.00 77.89 ? 47 TYR E O 1 ATOM 5041 C CB . TYR E 2 47 ? 105.999 23.194 33.510 1.00 73.15 ? 47 TYR E CB 1 ATOM 5042 C CG . TYR E 2 47 ? 106.593 24.455 32.922 1.00 69.44 ? 47 TYR E CG 1 ATOM 5043 C CD1 . TYR E 2 47 ? 106.630 25.641 33.650 1.00 67.94 ? 47 TYR E CD1 1 ATOM 5044 C CD2 . TYR E 2 47 ? 107.101 24.466 31.621 1.00 67.24 ? 47 TYR E CD2 1 ATOM 5045 C CE1 . TYR E 2 47 ? 107.160 26.816 33.095 1.00 67.56 ? 47 TYR E CE1 1 ATOM 5046 C CE2 . TYR E 2 47 ? 107.631 25.633 31.054 1.00 66.02 ? 47 TYR E CE2 1 ATOM 5047 C CZ . TYR E 2 47 ? 107.657 26.802 31.796 1.00 66.79 ? 47 TYR E CZ 1 ATOM 5048 O OH . TYR E 2 47 ? 108.170 27.951 31.238 1.00 61.56 ? 47 TYR E OH 1 ATOM 5049 N N . ARG E 2 48 ? 103.670 21.377 32.282 1.00 79.28 ? 48 ARG E N 1 ATOM 5050 C CA . ARG E 2 48 ? 103.187 20.033 31.994 1.00 80.36 ? 48 ARG E CA 1 ATOM 5051 C C . ARG E 2 48 ? 104.050 19.510 30.849 1.00 78.40 ? 48 ARG E C 1 ATOM 5052 O O . ARG E 2 48 ? 104.377 20.255 29.924 1.00 80.13 ? 48 ARG E O 1 ATOM 5053 C CB . ARG E 2 48 ? 101.719 20.063 31.547 1.00 85.06 ? 48 ARG E CB 1 ATOM 5054 C CG . ARG E 2 48 ? 100.731 20.630 32.558 1.00 92.23 ? 48 ARG E CG 1 ATOM 5055 C CD . ARG E 2 48 ? 100.642 19.773 33.818 1.00 100.73 ? 48 ARG E CD 1 ATOM 5056 N NE . ARG E 2 48 ? 99.541 20.197 34.689 1.00 109.20 ? 48 ARG E NE 1 ATOM 5057 C CZ . ARG E 2 48 ? 99.268 19.668 35.883 1.00 112.32 ? 48 ARG E CZ 1 ATOM 5058 N NH1 . ARG E 2 48 ? 100.020 18.684 36.367 1.00 115.43 ? 48 ARG E NH1 1 ATOM 5059 N NH2 . ARG E 2 48 ? 98.240 20.118 36.595 1.00 110.45 ? 48 ARG E NH2 1 ATOM 5060 N N . ALA E 2 49 ? 104.441 18.244 30.912 1.00 74.58 ? 49 ALA E N 1 ATOM 5061 C CA . ALA E 2 49 ? 105.245 17.670 29.843 1.00 71.25 ? 49 ALA E CA 1 ATOM 5062 C C . ALA E 2 49 ? 104.304 16.874 28.944 1.00 70.67 ? 49 ALA E C 1 ATOM 5063 O O . ALA E 2 49 ? 103.772 15.835 29.349 1.00 70.21 ? 49 ALA E O 1 ATOM 5064 C CB . ALA E 2 49 ? 106.328 16.765 30.421 1.00 68.46 ? 49 ALA E CB 1 ATOM 5065 N N . VAL E 2 50 ? 104.078 17.371 27.731 1.00 69.04 ? 50 VAL E N 1 ATOM 5066 C CA . VAL E 2 50 ? 103.198 16.689 26.793 1.00 66.93 ? 50 VAL E CA 1 ATOM 5067 C C . VAL E 2 50 ? 103.785 15.324 26.417 1.00 68.54 ? 50 VAL E C 1 ATOM 5068 O O . VAL E 2 50 ? 103.123 14.298 26.584 1.00 69.52 ? 50 VAL E O 1 ATOM 5069 C CB . VAL E 2 50 ? 102.983 17.525 25.525 1.00 63.39 ? 50 VAL E CB 1 ATOM 5070 C CG1 . VAL E 2 50 ? 101.934 16.872 24.659 1.00 64.34 ? 50 VAL E CG1 1 ATOM 5071 C CG2 . VAL E 2 50 ? 102.551 18.926 25.899 1.00 60.48 ? 50 VAL E CG2 1 ATOM 5072 N N . THR E 2 51 ? 105.022 15.310 25.918 1.00 68.19 ? 51 THR E N 1 ATOM 5073 C CA . THR E 2 51 ? 105.688 14.057 25.549 1.00 67.77 ? 51 THR E CA 1 ATOM 5074 C C . THR E 2 51 ? 106.839 13.800 26.501 1.00 68.07 ? 51 THR E C 1 ATOM 5075 O O . THR E 2 51 ? 107.380 14.729 27.089 1.00 69.91 ? 51 THR E O 1 ATOM 5076 C CB . THR E 2 51 ? 106.284 14.107 24.146 1.00 66.97 ? 51 THR E CB 1 ATOM 5077 O OG1 . THR E 2 51 ? 107.473 14.904 24.171 1.00 70.32 ? 51 THR E OG1 1 ATOM 5078 C CG2 . THR E 2 51 ? 105.296 14.708 23.167 1.00 67.11 ? 51 THR E CG2 1 ATOM 5079 N N . GLU E 2 52 ? 107.231 12.545 26.640 1.00 69.56 ? 52 GLU E N 1 ATOM 5080 C CA . GLU E 2 52 ? 108.325 12.208 27.537 1.00 76.17 ? 52 GLU E CA 1 ATOM 5081 C C . GLU E 2 52 ? 109.582 13.051 27.374 1.00 75.55 ? 52 GLU E C 1 ATOM 5082 O O . GLU E 2 52 ? 110.423 13.112 28.272 1.00 73.80 ? 52 GLU E O 1 ATOM 5083 C CB . GLU E 2 52 ? 108.682 10.735 27.381 1.00 85.09 ? 52 GLU E CB 1 ATOM 5084 C CG . GLU E 2 52 ? 107.699 9.819 28.066 1.00 95.76 ? 52 GLU E CG 1 ATOM 5085 C CD . GLU E 2 52 ? 107.392 10.298 29.465 1.00 102.40 ? 52 GLU E CD 1 ATOM 5086 O OE1 . GLU E 2 52 ? 106.653 11.302 29.592 1.00 103.91 ? 52 GLU E OE1 1 ATOM 5087 O OE2 . GLU E 2 52 ? 107.906 9.686 30.429 1.00 106.96 ? 52 GLU E OE2 1 ATOM 5088 N N . LEU E 2 53 ? 109.705 13.705 26.230 1.00 76.93 ? 53 LEU E N 1 ATOM 5089 C CA . LEU E 2 53 ? 110.870 14.529 25.949 1.00 78.71 ? 53 LEU E CA 1 ATOM 5090 C C . LEU E 2 53 ? 111.024 15.714 26.906 1.00 79.55 ? 53 LEU E C 1 ATOM 5091 O O . LEU E 2 53 ? 112.137 16.193 27.130 1.00 80.91 ? 53 LEU E O 1 ATOM 5092 C CB . LEU E 2 53 ? 110.791 15.042 24.513 1.00 78.23 ? 53 LEU E CB 1 ATOM 5093 C CG . LEU E 2 53 ? 112.122 15.422 23.880 1.00 78.35 ? 53 LEU E CG 1 ATOM 5094 C CD1 . LEU E 2 53 ? 112.977 14.170 23.755 1.00 78.36 ? 53 LEU E CD1 1 ATOM 5095 C CD2 . LEU E 2 53 ? 111.881 16.055 22.517 1.00 77.68 ? 53 LEU E CD2 1 ATOM 5096 N N . GLY E 2 54 ? 109.911 16.183 27.464 1.00 79.33 ? 54 GLY E N 1 ATOM 5097 C CA . GLY E 2 54 ? 109.961 17.317 28.369 1.00 79.68 ? 54 GLY E CA 1 ATOM 5098 C C . GLY E 2 54 ? 109.988 16.945 29.837 1.00 80.88 ? 54 GLY E C 1 ATOM 5099 O O . GLY E 2 54 ? 110.369 17.759 30.681 1.00 82.60 ? 54 GLY E O 1 ATOM 5100 N N . ARG E 2 55 ? 109.589 15.714 30.134 1.00 80.27 ? 55 ARG E N 1 ATOM 5101 C CA . ARG E 2 55 ? 109.543 15.202 31.498 1.00 80.58 ? 55 ARG E CA 1 ATOM 5102 C C . ARG E 2 55 ? 110.482 15.887 32.494 1.00 81.32 ? 55 ARG E C 1 ATOM 5103 O O . ARG E 2 55 ? 110.024 16.490 33.459 1.00 81.33 ? 55 ARG E O 1 ATOM 5104 C CB . ARG E 2 55 ? 109.825 13.703 31.489 1.00 82.20 ? 55 ARG E CB 1 ATOM 5105 C CG . ARG E 2 55 ? 109.857 13.086 32.866 1.00 86.86 ? 55 ARG E CG 1 ATOM 5106 C CD . ARG E 2 55 ? 108.647 12.208 33.091 1.00 90.62 ? 55 ARG E CD 1 ATOM 5107 N NE . ARG E 2 55 ? 107.397 12.907 32.808 1.00 93.39 ? 55 ARG E NE 1 ATOM 5108 C CZ . ARG E 2 55 ? 106.194 12.367 32.973 1.00 95.36 ? 55 ARG E CZ 1 ATOM 5109 N NH1 . ARG E 2 55 ? 106.086 11.120 33.419 1.00 97.63 ? 55 ARG E NH1 1 ATOM 5110 N NH2 . ARG E 2 55 ? 105.102 13.066 32.693 1.00 94.62 ? 55 ARG E NH2 1 ATOM 5111 N N . PRO E 2 56 ? 111.808 15.807 32.274 1.00 83.42 ? 56 PRO E N 1 ATOM 5112 C CA . PRO E 2 56 ? 112.761 16.441 33.196 1.00 84.49 ? 56 PRO E CA 1 ATOM 5113 C C . PRO E 2 56 ? 112.478 17.929 33.385 1.00 85.44 ? 56 PRO E C 1 ATOM 5114 O O . PRO E 2 56 ? 112.118 18.374 34.482 1.00 85.87 ? 56 PRO E O 1 ATOM 5115 C CB . PRO E 2 56 ? 114.112 16.215 32.515 1.00 83.44 ? 56 PRO E CB 1 ATOM 5116 C CG . PRO E 2 56 ? 113.897 14.988 31.712 1.00 83.74 ? 56 PRO E CG 1 ATOM 5117 C CD . PRO E 2 56 ? 112.521 15.212 31.133 1.00 83.99 ? 56 PRO E CD 1 ATOM 5118 N N . ASP E 2 57 ? 112.660 18.681 32.298 1.00 84.94 ? 57 ASP E N 1 ATOM 5119 C CA . ASP E 2 57 ? 112.443 20.119 32.286 1.00 84.68 ? 57 ASP E CA 1 ATOM 5120 C C . ASP E 2 57 ? 111.179 20.445 33.039 1.00 84.03 ? 57 ASP E C 1 ATOM 5121 O O . ASP E 2 57 ? 111.215 21.139 34.046 1.00 84.78 ? 57 ASP E O 1 ATOM 5122 C CB . ASP E 2 57 ? 112.332 20.634 30.850 1.00 87.46 ? 57 ASP E CB 1 ATOM 5123 C CG . ASP E 2 57 ? 113.659 20.580 30.100 1.00 92.03 ? 57 ASP E CG 1 ATOM 5124 O OD1 . ASP E 2 57 ? 114.279 19.498 30.076 1.00 95.55 ? 57 ASP E OD1 1 ATOM 5125 O OD2 . ASP E 2 57 ? 114.080 21.613 29.528 1.00 92.84 ? 57 ASP E OD2 1 ATOM 5126 N N . ALA E 2 58 ? 110.060 19.926 32.555 1.00 84.73 ? 58 ALA E N 1 ATOM 5127 C CA . ALA E 2 58 ? 108.773 20.168 33.191 1.00 88.49 ? 58 ALA E CA 1 ATOM 5128 C C . ALA E 2 58 ? 108.801 19.914 34.696 1.00 90.31 ? 58 ALA E C 1 ATOM 5129 O O . ALA E 2 58 ? 108.530 20.817 35.489 1.00 90.60 ? 58 ALA E O 1 ATOM 5130 C CB . ALA E 2 58 ? 107.708 19.299 32.548 1.00 89.80 ? 58 ALA E CB 1 ATOM 5131 N N . GLU E 2 59 ? 109.124 18.685 35.085 1.00 92.79 ? 59 GLU E N 1 ATOM 5132 C CA . GLU E 2 59 ? 109.164 18.318 36.497 1.00 95.72 ? 59 GLU E CA 1 ATOM 5133 C C . GLU E 2 59 ? 110.161 19.137 37.301 1.00 95.42 ? 59 GLU E C 1 ATOM 5134 O O . GLU E 2 59 ? 110.111 19.164 38.533 1.00 94.90 ? 59 GLU E O 1 ATOM 5135 C CB . GLU E 2 59 ? 109.470 16.822 36.660 1.00 99.67 ? 59 GLU E CB 1 ATOM 5136 C CG . GLU E 2 59 ? 108.302 15.901 36.294 1.00 103.53 ? 59 GLU E CG 1 ATOM 5137 C CD . GLU E 2 59 ? 108.491 14.476 36.794 1.00 105.26 ? 59 GLU E CD 1 ATOM 5138 O OE1 . GLU E 2 59 ? 109.474 13.823 36.384 1.00 106.25 ? 59 GLU E OE1 1 ATOM 5139 O OE2 . GLU E 2 59 ? 107.654 14.009 37.599 1.00 106.45 ? 59 GLU E OE2 1 ATOM 5140 N N . TYR E 2 60 ? 111.070 19.808 36.607 1.00 95.87 ? 60 TYR E N 1 ATOM 5141 C CA . TYR E 2 60 ? 112.049 20.628 37.294 1.00 96.66 ? 60 TYR E CA 1 ATOM 5142 C C . TYR E 2 60 ? 111.524 22.046 37.517 1.00 97.09 ? 60 TYR E C 1 ATOM 5143 O O . TYR E 2 60 ? 111.380 22.477 38.653 1.00 97.88 ? 60 TYR E O 1 ATOM 5144 C CB . TYR E 2 60 ? 113.356 20.685 36.513 1.00 96.16 ? 60 TYR E CB 1 ATOM 5145 C CG . TYR E 2 60 ? 114.357 21.584 37.178 1.00 97.46 ? 60 TYR E CG 1 ATOM 5146 C CD1 . TYR E 2 60 ? 114.865 21.281 38.437 1.00 97.64 ? 60 TYR E CD1 1 ATOM 5147 C CD2 . TYR E 2 60 ? 114.753 22.773 36.577 1.00 99.21 ? 60 TYR E CD2 1 ATOM 5148 C CE1 . TYR E 2 60 ? 115.746 22.147 39.085 1.00 99.39 ? 60 TYR E CE1 1 ATOM 5149 C CE2 . TYR E 2 60 ? 115.632 23.647 37.213 1.00 99.50 ? 60 TYR E CE2 1 ATOM 5150 C CZ . TYR E 2 60 ? 116.125 23.330 38.464 1.00 99.28 ? 60 TYR E CZ 1 ATOM 5151 O OH . TYR E 2 60 ? 116.995 24.198 39.084 1.00 99.59 ? 60 TYR E OH 1 ATOM 5152 N N . TRP E 2 61 ? 111.241 22.769 36.437 1.00 96.22 ? 61 TRP E N 1 ATOM 5153 C CA . TRP E 2 61 ? 110.731 24.133 36.546 1.00 94.45 ? 61 TRP E CA 1 ATOM 5154 C C . TRP E 2 61 ? 109.758 24.281 37.710 1.00 92.32 ? 61 TRP E C 1 ATOM 5155 O O . TRP E 2 61 ? 109.898 25.179 38.532 1.00 91.24 ? 61 TRP E O 1 ATOM 5156 C CB . TRP E 2 61 ? 110.019 24.549 35.255 1.00 99.98 ? 61 TRP E CB 1 ATOM 5157 C CG . TRP E 2 61 ? 110.904 24.697 34.037 1.00 105.80 ? 61 TRP E CG 1 ATOM 5158 C CD1 . TRP E 2 61 ? 110.520 24.580 32.725 1.00 107.55 ? 61 TRP E CD1 1 ATOM 5159 C CD2 . TRP E 2 61 ? 112.304 24.990 34.015 1.00 108.42 ? 61 TRP E CD2 1 ATOM 5160 N NE1 . TRP E 2 61 ? 111.594 24.776 31.892 1.00 107.11 ? 61 TRP E NE1 1 ATOM 5161 C CE2 . TRP E 2 61 ? 112.702 25.029 32.656 1.00 109.33 ? 61 TRP E CE2 1 ATOM 5162 C CE3 . TRP E 2 61 ? 113.262 25.225 35.008 1.00 110.07 ? 61 TRP E CE3 1 ATOM 5163 C CZ2 . TRP E 2 61 ? 114.018 25.291 32.268 1.00 111.58 ? 61 TRP E CZ2 1 ATOM 5164 C CZ3 . TRP E 2 61 ? 114.571 25.487 34.622 1.00 113.88 ? 61 TRP E CZ3 1 ATOM 5165 C CH2 . TRP E 2 61 ? 114.937 25.517 33.261 1.00 113.93 ? 61 TRP E CH2 1 ATOM 5166 N N . ASN E 2 62 ? 108.772 23.395 37.785 1.00 90.90 ? 62 ASN E N 1 ATOM 5167 C CA . ASN E 2 62 ? 107.782 23.470 38.853 1.00 91.36 ? 62 ASN E CA 1 ATOM 5168 C C . ASN E 2 62 ? 108.400 23.332 40.245 1.00 93.69 ? 62 ASN E C 1 ATOM 5169 O O . ASN E 2 62 ? 107.782 23.697 41.245 1.00 92.15 ? 62 ASN E O 1 ATOM 5170 C CB . ASN E 2 62 ? 106.702 22.392 38.670 1.00 88.05 ? 62 ASN E CB 1 ATOM 5171 C CG . ASN E 2 62 ? 105.876 22.581 37.403 1.00 81.73 ? 62 ASN E CG 1 ATOM 5172 O OD1 . ASN E 2 62 ? 104.841 21.940 37.228 1.00 75.57 ? 62 ASN E OD1 1 ATOM 5173 N ND2 . ASN E 2 62 ? 106.335 23.449 36.514 1.00 79.83 ? 62 ASN E ND2 1 ATOM 5174 N N . SER E 2 63 ? 109.620 22.811 40.305 1.00 98.94 ? 63 SER E N 1 ATOM 5175 C CA . SER E 2 63 ? 110.309 22.609 41.581 1.00 105.43 ? 63 SER E CA 1 ATOM 5176 C C . SER E 2 63 ? 110.612 23.904 42.327 1.00 108.66 ? 63 SER E C 1 ATOM 5177 O O . SER E 2 63 ? 110.461 23.972 43.549 1.00 108.54 ? 63 SER E O 1 ATOM 5178 C CB . SER E 2 63 ? 111.622 21.841 41.366 1.00 106.47 ? 63 SER E CB 1 ATOM 5179 O OG . SER E 2 63 ? 112.585 22.632 40.685 1.00 105.32 ? 63 SER E OG 1 ATOM 5180 N N . GLN E 2 64 ? 111.048 24.922 41.588 1.00 112.64 ? 64 GLN E N 1 ATOM 5181 C CA . GLN E 2 64 ? 111.384 26.220 42.171 1.00 115.49 ? 64 GLN E CA 1 ATOM 5182 C C . GLN E 2 64 ? 110.260 27.251 42.001 1.00 117.14 ? 64 GLN E C 1 ATOM 5183 O O . GLN E 2 64 ? 110.074 27.809 40.917 1.00 117.59 ? 64 GLN E O 1 ATOM 5184 C CB . GLN E 2 64 ? 112.685 26.738 41.545 1.00 114.16 ? 64 GLN E CB 1 ATOM 5185 C CG . GLN E 2 64 ? 112.664 26.814 40.030 1.00 113.39 ? 64 GLN E CG 1 ATOM 5186 C CD . GLN E 2 64 ? 114.055 26.791 39.431 1.00 115.10 ? 64 GLN E CD 1 ATOM 5187 O OE1 . GLN E 2 64 ? 114.230 26.962 38.223 1.00 114.84 ? 64 GLN E OE1 1 ATOM 5188 N NE2 . GLN E 2 64 ? 115.055 26.570 40.276 1.00 116.61 ? 64 GLN E NE2 1 ATOM 5189 N N . LYS E 2 65 ? 109.519 27.497 43.084 1.00 117.98 ? 65 LYS E N 1 ATOM 5190 C CA . LYS E 2 65 ? 108.404 28.446 43.080 1.00 117.82 ? 65 LYS E CA 1 ATOM 5191 C C . LYS E 2 65 ? 108.866 29.889 42.910 1.00 116.73 ? 65 LYS E C 1 ATOM 5192 O O . LYS E 2 65 ? 108.194 30.828 43.340 1.00 116.11 ? 65 LYS E O 1 ATOM 5193 C CB . LYS E 2 65 ? 107.589 28.316 44.375 1.00 119.36 ? 65 LYS E CB 1 ATOM 5194 C CG . LYS E 2 65 ? 106.975 26.935 44.600 1.00 120.19 ? 65 LYS E CG 1 ATOM 5195 C CD . LYS E 2 65 ? 106.215 26.452 43.369 1.00 121.10 ? 65 LYS E CD 1 ATOM 5196 C CE . LYS E 2 65 ? 105.461 25.156 43.632 1.00 122.32 ? 65 LYS E CE 1 ATOM 5197 N NZ . LYS E 2 65 ? 104.337 25.344 44.596 1.00 123.47 ? 65 LYS E NZ 1 ATOM 5198 N N . ASP E 2 66 ? 110.025 30.046 42.281 1.00 115.88 ? 66 ASP E N 1 ATOM 5199 C CA . ASP E 2 66 ? 110.623 31.350 42.014 1.00 114.79 ? 66 ASP E CA 1 ATOM 5200 C C . ASP E 2 66 ? 110.388 31.574 40.526 1.00 111.65 ? 66 ASP E C 1 ATOM 5201 O O . ASP E 2 66 ? 109.699 32.508 40.103 1.00 109.64 ? 66 ASP E O 1 ATOM 5202 C CB . ASP E 2 66 ? 112.128 31.283 42.307 1.00 118.34 ? 66 ASP E CB 1 ATOM 5203 C CG . ASP E 2 66 ? 112.791 32.647 42.316 1.00 121.68 ? 66 ASP E CG 1 ATOM 5204 O OD1 . ASP E 2 66 ? 112.451 33.474 43.195 1.00 123.64 ? 66 ASP E OD1 1 ATOM 5205 O OD2 . ASP E 2 66 ? 113.660 32.887 41.447 1.00 122.52 ? 66 ASP E OD2 1 ATOM 5206 N N . PHE E 2 67 ? 110.976 30.670 39.751 1.00 109.08 ? 67 PHE E N 1 ATOM 5207 C CA . PHE E 2 67 ? 110.889 30.645 38.299 1.00 105.25 ? 67 PHE E CA 1 ATOM 5208 C C . PHE E 2 67 ? 109.429 30.383 37.954 1.00 102.50 ? 67 PHE E C 1 ATOM 5209 O O . PHE E 2 67 ? 108.845 31.056 37.110 1.00 101.69 ? 67 PHE E O 1 ATOM 5210 C CB . PHE E 2 67 ? 111.791 29.511 37.795 1.00 104.61 ? 67 PHE E CB 1 ATOM 5211 C CG . PHE E 2 67 ? 111.915 29.421 36.305 1.00 103.39 ? 67 PHE E CG 1 ATOM 5212 C CD1 . PHE E 2 67 ? 113.127 29.046 35.736 1.00 104.22 ? 67 PHE E CD1 1 ATOM 5213 C CD2 . PHE E 2 67 ? 110.827 29.650 35.473 1.00 103.35 ? 67 PHE E CD2 1 ATOM 5214 C CE1 . PHE E 2 67 ? 113.256 28.897 34.365 1.00 104.91 ? 67 PHE E CE1 1 ATOM 5215 C CE2 . PHE E 2 67 ? 110.943 29.503 34.096 1.00 104.84 ? 67 PHE E CE2 1 ATOM 5216 C CZ . PHE E 2 67 ? 112.161 29.125 33.540 1.00 105.35 ? 67 PHE E CZ 1 ATOM 5217 N N . LEU E 2 68 ? 108.851 29.401 38.635 1.00 100.57 ? 68 LEU E N 1 ATOM 5218 C CA . LEU E 2 68 ? 107.461 29.014 38.442 1.00 98.29 ? 68 LEU E CA 1 ATOM 5219 C C . LEU E 2 68 ? 106.507 30.122 38.889 1.00 98.79 ? 68 LEU E C 1 ATOM 5220 O O . LEU E 2 68 ? 105.337 30.144 38.502 1.00 98.95 ? 68 LEU E O 1 ATOM 5221 C CB . LEU E 2 68 ? 107.177 27.734 39.228 1.00 94.10 ? 68 LEU E CB 1 ATOM 5222 C CG . LEU E 2 68 ? 105.766 27.162 39.158 1.00 90.32 ? 68 LEU E CG 1 ATOM 5223 C CD1 . LEU E 2 68 ? 105.402 26.853 37.720 1.00 89.66 ? 68 LEU E CD1 1 ATOM 5224 C CD2 . LEU E 2 68 ? 105.698 25.910 40.004 1.00 90.89 ? 68 LEU E CD2 1 ATOM 5225 N N . GLU E 2 69 ? 107.008 31.039 39.709 1.00 98.70 ? 69 GLU E N 1 ATOM 5226 C CA . GLU E 2 69 ? 106.189 32.143 40.189 1.00 98.32 ? 69 GLU E CA 1 ATOM 5227 C C . GLU E 2 69 ? 106.435 33.346 39.295 1.00 98.00 ? 69 GLU E C 1 ATOM 5228 O O . GLU E 2 69 ? 105.611 34.260 39.212 1.00 98.11 ? 69 GLU E O 1 ATOM 5229 C CB . GLU E 2 69 ? 106.553 32.494 41.631 1.00 98.17 ? 69 GLU E CB 1 ATOM 5230 C CG . GLU E 2 69 ? 105.624 33.517 42.272 1.00 98.37 ? 69 GLU E CG 1 ATOM 5231 C CD . GLU E 2 69 ? 104.242 32.957 42.576 1.00 98.52 ? 69 GLU E CD 1 ATOM 5232 O OE1 . GLU E 2 69 ? 104.154 31.985 43.360 1.00 98.12 ? 69 GLU E OE1 1 ATOM 5233 O OE2 . GLU E 2 69 ? 103.248 33.492 42.036 1.00 97.60 ? 69 GLU E OE2 1 ATOM 5234 N N . ASP E 2 70 ? 107.580 33.333 38.625 1.00 97.03 ? 70 ASP E N 1 ATOM 5235 C CA . ASP E 2 70 ? 107.959 34.412 37.727 1.00 97.20 ? 70 ASP E CA 1 ATOM 5236 C C . ASP E 2 70 ? 107.107 34.378 36.449 1.00 97.10 ? 70 ASP E C 1 ATOM 5237 O O . ASP E 2 70 ? 106.697 35.423 35.933 1.00 95.82 ? 70 ASP E O 1 ATOM 5238 C CB . ASP E 2 70 ? 109.448 34.284 37.396 1.00 98.41 ? 70 ASP E CB 1 ATOM 5239 C CG . ASP E 2 70 ? 109.977 35.464 36.615 1.00 100.47 ? 70 ASP E CG 1 ATOM 5240 O OD1 . ASP E 2 70 ? 111.216 35.585 36.483 1.00 100.17 ? 70 ASP E OD1 1 ATOM 5241 O OD2 . ASP E 2 70 ? 109.157 36.267 36.127 1.00 103.15 ? 70 ASP E OD2 1 ATOM 5242 N N . ARG E 2 71 ? 106.833 33.168 35.959 1.00 96.96 ? 71 ARG E N 1 ATOM 5243 C CA . ARG E 2 71 ? 106.033 32.963 34.749 1.00 94.31 ? 71 ARG E CA 1 ATOM 5244 C C . ARG E 2 71 ? 104.552 33.252 34.991 1.00 94.31 ? 71 ARG E C 1 ATOM 5245 O O . ARG E 2 71 ? 103.839 33.676 34.082 1.00 95.82 ? 71 ARG E O 1 ATOM 5246 C CB . ARG E 2 71 ? 106.178 31.519 34.252 1.00 90.06 ? 71 ARG E CB 1 ATOM 5247 C CG . ARG E 2 71 ? 107.590 31.101 33.880 1.00 86.28 ? 71 ARG E CG 1 ATOM 5248 C CD . ARG E 2 71 ? 108.025 31.621 32.520 1.00 83.95 ? 71 ARG E CD 1 ATOM 5249 N NE . ARG E 2 71 ? 109.380 31.173 32.202 1.00 85.85 ? 71 ARG E NE 1 ATOM 5250 C CZ . ARG E 2 71 ? 109.946 31.254 31.000 1.00 86.42 ? 71 ARG E CZ 1 ATOM 5251 N NH1 . ARG E 2 71 ? 109.274 31.764 29.982 1.00 86.63 ? 71 ARG E NH1 1 ATOM 5252 N NH2 . ARG E 2 71 ? 111.190 30.825 30.812 1.00 86.69 ? 71 ARG E NH2 1 ATOM 5253 N N . ARG E 2 72 ? 104.095 33.016 36.216 1.00 93.15 ? 72 ARG E N 1 ATOM 5254 C CA . ARG E 2 72 ? 102.697 33.238 36.580 1.00 94.44 ? 72 ARG E CA 1 ATOM 5255 C C . ARG E 2 72 ? 102.148 34.635 36.282 1.00 95.91 ? 72 ARG E C 1 ATOM 5256 O O . ARG E 2 72 ? 101.089 34.773 35.659 1.00 96.44 ? 72 ARG E O 1 ATOM 5257 C CB . ARG E 2 72 ? 102.501 32.964 38.065 1.00 95.05 ? 72 ARG E CB 1 ATOM 5258 C CG . ARG E 2 72 ? 101.551 31.834 38.382 1.00 94.36 ? 72 ARG E CG 1 ATOM 5259 C CD . ARG E 2 72 ? 102.318 30.631 38.876 1.00 92.27 ? 72 ARG E CD 1 ATOM 5260 N NE . ARG E 2 72 ? 101.488 29.782 39.720 1.00 91.91 ? 72 ARG E NE 1 ATOM 5261 C CZ . ARG E 2 72 ? 101.933 28.704 40.355 1.00 91.59 ? 72 ARG E CZ 1 ATOM 5262 N NH1 . ARG E 2 72 ? 103.206 28.348 40.233 1.00 90.45 ? 72 ARG E NH1 1 ATOM 5263 N NH2 . ARG E 2 72 ? 101.111 27.988 41.114 1.00 90.86 ? 72 ARG E NH2 1 ATOM 5264 N N . ALA E 2 73 ? 102.866 35.662 36.740 1.00 95.32 ? 73 ALA E N 1 ATOM 5265 C CA . ALA E 2 73 ? 102.452 37.057 36.567 1.00 92.75 ? 73 ALA E CA 1 ATOM 5266 C C . ALA E 2 73 ? 102.651 37.658 35.178 1.00 91.34 ? 73 ALA E C 1 ATOM 5267 O O . ALA E 2 73 ? 102.358 38.837 34.968 1.00 90.70 ? 73 ALA E O 1 ATOM 5268 C CB . ALA E 2 73 ? 103.149 37.924 37.596 1.00 93.48 ? 73 ALA E CB 1 ATOM 5269 N N . ALA E 2 74 ? 103.147 36.862 34.236 1.00 90.16 ? 74 ALA E N 1 ATOM 5270 C CA . ALA E 2 74 ? 103.360 37.340 32.875 1.00 86.99 ? 74 ALA E CA 1 ATOM 5271 C C . ALA E 2 74 ? 102.029 37.793 32.294 1.00 85.50 ? 74 ALA E C 1 ATOM 5272 O O . ALA E 2 74 ? 101.987 38.649 31.413 1.00 82.94 ? 74 ALA E O 1 ATOM 5273 C CB . ALA E 2 74 ? 103.956 36.237 32.017 1.00 86.50 ? 74 ALA E CB 1 ATOM 5274 N N . VAL E 2 75 ? 100.944 37.211 32.799 1.00 85.78 ? 75 VAL E N 1 ATOM 5275 C CA . VAL E 2 75 ? 99.598 37.551 32.346 1.00 87.12 ? 75 VAL E CA 1 ATOM 5276 C C . VAL E 2 75 ? 99.416 39.067 32.406 1.00 88.23 ? 75 VAL E C 1 ATOM 5277 O O . VAL E 2 75 ? 98.650 39.652 31.635 1.00 88.07 ? 75 VAL E O 1 ATOM 5278 C CB . VAL E 2 75 ? 98.513 36.872 33.235 1.00 86.28 ? 75 VAL E CB 1 ATOM 5279 C CG1 . VAL E 2 75 ? 98.633 35.364 33.149 1.00 86.95 ? 75 VAL E CG1 1 ATOM 5280 C CG2 . VAL E 2 75 ? 98.663 37.309 34.678 1.00 85.40 ? 75 VAL E CG2 1 ATOM 5281 N N . ASP E 2 76 ? 100.144 39.690 33.329 1.00 88.81 ? 76 ASP E N 1 ATOM 5282 C CA . ASP E 2 76 ? 100.102 41.132 33.541 1.00 87.31 ? 76 ASP E CA 1 ATOM 5283 C C . ASP E 2 76 ? 101.422 41.785 33.137 1.00 86.69 ? 76 ASP E C 1 ATOM 5284 O O . ASP E 2 76 ? 101.452 42.683 32.289 1.00 88.47 ? 76 ASP E O 1 ATOM 5285 C CB . ASP E 2 76 ? 99.821 41.445 35.017 1.00 85.35 ? 76 ASP E CB 1 ATOM 5286 C CG . ASP E 2 76 ? 98.431 41.022 35.455 1.00 85.94 ? 76 ASP E CG 1 ATOM 5287 O OD1 . ASP E 2 76 ? 97.459 41.384 34.754 1.00 89.02 ? 76 ASP E OD1 1 ATOM 5288 O OD2 . ASP E 2 76 ? 98.309 40.341 36.500 1.00 81.77 ? 76 ASP E OD2 1 ATOM 5289 N N . THR E 2 77 ? 102.511 41.323 33.746 1.00 83.86 ? 77 THR E N 1 ATOM 5290 C CA . THR E 2 77 ? 103.843 41.865 33.479 1.00 80.70 ? 77 THR E CA 1 ATOM 5291 C C . THR E 2 77 ? 104.266 41.775 32.021 1.00 78.47 ? 77 THR E C 1 ATOM 5292 O O . THR E 2 77 ? 104.996 42.631 31.525 1.00 75.27 ? 77 THR E O 1 ATOM 5293 C CB . THR E 2 77 ? 104.914 41.144 34.325 1.00 80.77 ? 77 THR E CB 1 ATOM 5294 O OG1 . THR E 2 77 ? 105.028 39.776 33.905 1.00 81.09 ? 77 THR E OG1 1 ATOM 5295 C CG2 . THR E 2 77 ? 104.533 41.179 35.797 1.00 81.63 ? 77 THR E CG2 1 ATOM 5296 N N . TYR E 2 78 ? 103.789 40.735 31.344 1.00 79.03 ? 78 TYR E N 1 ATOM 5297 C CA . TYR E 2 78 ? 104.133 40.468 29.947 1.00 78.96 ? 78 TYR E CA 1 ATOM 5298 C C . TYR E 2 78 ? 102.972 40.683 28.979 1.00 77.37 ? 78 TYR E C 1 ATOM 5299 O O . TYR E 2 78 ? 103.046 41.522 28.077 1.00 75.43 ? 78 TYR E O 1 ATOM 5300 C CB . TYR E 2 78 ? 104.642 39.019 29.840 1.00 79.61 ? 78 TYR E CB 1 ATOM 5301 C CG . TYR E 2 78 ? 104.950 38.515 28.447 1.00 78.61 ? 78 TYR E CG 1 ATOM 5302 C CD1 . TYR E 2 78 ? 106.010 39.042 27.705 1.00 76.54 ? 78 TYR E CD1 1 ATOM 5303 C CD2 . TYR E 2 78 ? 104.199 37.479 27.885 1.00 79.90 ? 78 TYR E CD2 1 ATOM 5304 C CE1 . TYR E 2 78 ? 106.317 38.542 26.434 1.00 79.31 ? 78 TYR E CE1 1 ATOM 5305 C CE2 . TYR E 2 78 ? 104.494 36.973 26.617 1.00 81.42 ? 78 TYR E CE2 1 ATOM 5306 C CZ . TYR E 2 78 ? 105.555 37.506 25.896 1.00 81.27 ? 78 TYR E CZ 1 ATOM 5307 O OH . TYR E 2 78 ? 105.853 36.997 24.648 1.00 79.63 ? 78 TYR E OH 1 ATOM 5308 N N . CYS E 2 79 ? 101.904 39.918 29.174 1.00 76.25 ? 79 CYS E N 1 ATOM 5309 C CA . CYS E 2 79 ? 100.742 40.003 28.305 1.00 75.35 ? 79 CYS E CA 1 ATOM 5310 C C . CYS E 2 79 ? 100.089 41.380 28.295 1.00 74.59 ? 79 CYS E C 1 ATOM 5311 O O . CYS E 2 79 ? 100.342 42.183 27.391 1.00 74.47 ? 79 CYS E O 1 ATOM 5312 C CB . CYS E 2 79 ? 99.719 38.919 28.680 1.00 75.46 ? 79 CYS E CB 1 ATOM 5313 S SG . CYS E 2 79 ? 100.225 37.211 28.248 1.00 76.85 ? 79 CYS E SG 1 ATOM 5314 N N . ARG E 2 80 ? 99.256 41.657 29.294 1.00 74.67 ? 80 ARG E N 1 ATOM 5315 C CA . ARG E 2 80 ? 98.565 42.944 29.378 1.00 72.45 ? 80 ARG E CA 1 ATOM 5316 C C . ARG E 2 80 ? 99.445 44.156 29.078 1.00 69.85 ? 80 ARG E C 1 ATOM 5317 O O . ARG E 2 80 ? 98.976 45.134 28.496 1.00 67.12 ? 80 ARG E O 1 ATOM 5318 C CB . ARG E 2 80 ? 97.896 43.085 30.746 1.00 71.13 ? 80 ARG E CB 1 ATOM 5319 C CG . ARG E 2 80 ? 96.485 42.544 30.738 1.00 72.77 ? 80 ARG E CG 1 ATOM 5320 C CD . ARG E 2 80 ? 96.030 42.091 32.102 1.00 76.23 ? 80 ARG E CD 1 ATOM 5321 N NE . ARG E 2 80 ? 94.664 41.574 32.042 1.00 81.15 ? 80 ARG E NE 1 ATOM 5322 C CZ . ARG E 2 80 ? 94.108 40.809 32.977 1.00 84.34 ? 80 ARG E CZ 1 ATOM 5323 N NH1 . ARG E 2 80 ? 94.804 40.465 34.057 1.00 84.76 ? 80 ARG E NH1 1 ATOM 5324 N NH2 . ARG E 2 80 ? 92.856 40.382 32.826 1.00 84.69 ? 80 ARG E NH2 1 ATOM 5325 N N . HIS E 2 81 ? 100.714 44.093 29.468 1.00 67.46 ? 81 HIS E N 1 ATOM 5326 C CA . HIS E 2 81 ? 101.622 45.195 29.189 1.00 66.47 ? 81 HIS E CA 1 ATOM 5327 C C . HIS E 2 81 ? 101.822 45.329 27.677 1.00 65.39 ? 81 HIS E C 1 ATOM 5328 O O . HIS E 2 81 ? 101.469 46.345 27.082 1.00 66.18 ? 81 HIS E O 1 ATOM 5329 C CB . HIS E 2 81 ? 102.986 44.970 29.848 1.00 68.37 ? 81 HIS E CB 1 ATOM 5330 C CG . HIS E 2 81 ? 104.028 45.964 29.423 1.00 71.37 ? 81 HIS E CG 1 ATOM 5331 N ND1 . HIS E 2 81 ? 104.193 47.186 30.041 1.00 71.98 ? 81 HIS E ND1 1 ATOM 5332 C CD2 . HIS E 2 81 ? 104.925 45.935 28.405 1.00 71.50 ? 81 HIS E CD2 1 ATOM 5333 C CE1 . HIS E 2 81 ? 105.144 47.866 29.422 1.00 72.11 ? 81 HIS E CE1 1 ATOM 5334 N NE2 . HIS E 2 81 ? 105.603 47.130 28.425 1.00 70.04 ? 81 HIS E NE2 1 ATOM 5335 N N . ASN E 2 82 ? 102.389 44.300 27.056 1.00 62.78 ? 82 ASN E N 1 ATOM 5336 C CA . ASN E 2 82 ? 102.640 44.341 25.622 1.00 59.49 ? 82 ASN E CA 1 ATOM 5337 C C . ASN E 2 82 ? 101.405 44.679 24.800 1.00 57.74 ? 82 ASN E C 1 ATOM 5338 O O . ASN E 2 82 ? 101.507 45.185 23.678 1.00 52.15 ? 82 ASN E O 1 ATOM 5339 C CB . ASN E 2 82 ? 103.224 43.011 25.157 1.00 60.32 ? 82 ASN E CB 1 ATOM 5340 C CG . ASN E 2 82 ? 104.672 42.844 25.560 1.00 61.06 ? 82 ASN E CG 1 ATOM 5341 O OD1 . ASN E 2 82 ? 105.512 43.690 25.256 1.00 59.28 ? 82 ASN E OD1 1 ATOM 5342 N ND2 . ASN E 2 82 ? 104.976 41.746 26.241 1.00 63.84 ? 82 ASN E ND2 1 ATOM 5343 N N . TYR E 2 83 ? 100.235 44.406 25.362 1.00 59.64 ? 83 TYR E N 1 ATOM 5344 C CA . TYR E 2 83 ? 98.993 44.682 24.657 1.00 64.98 ? 83 TYR E CA 1 ATOM 5345 C C . TYR E 2 83 ? 98.866 46.169 24.377 1.00 65.53 ? 83 TYR E C 1 ATOM 5346 O O . TYR E 2 83 ? 98.713 46.585 23.228 1.00 65.51 ? 83 TYR E O 1 ATOM 5347 C CB . TYR E 2 83 ? 97.794 44.217 25.486 1.00 66.94 ? 83 TYR E CB 1 ATOM 5348 C CG . TYR E 2 83 ? 96.470 44.262 24.742 1.00 70.57 ? 83 TYR E CG 1 ATOM 5349 C CD1 . TYR E 2 83 ? 96.043 45.422 24.095 1.00 71.04 ? 83 TYR E CD1 1 ATOM 5350 C CD2 . TYR E 2 83 ? 95.625 43.151 24.720 1.00 70.68 ? 83 TYR E CD2 1 ATOM 5351 C CE1 . TYR E 2 83 ? 94.805 45.472 23.449 1.00 73.11 ? 83 TYR E CE1 1 ATOM 5352 C CE2 . TYR E 2 83 ? 94.387 43.194 24.079 1.00 69.53 ? 83 TYR E CE2 1 ATOM 5353 C CZ . TYR E 2 83 ? 93.982 44.355 23.447 1.00 70.98 ? 83 TYR E CZ 1 ATOM 5354 O OH . TYR E 2 83 ? 92.754 44.402 22.825 1.00 70.44 ? 83 TYR E OH 1 ATOM 5355 N N . GLY E 2 84 ? 98.928 46.961 25.443 1.00 66.75 ? 84 GLY E N 1 ATOM 5356 C CA . GLY E 2 84 ? 98.803 48.403 25.318 1.00 66.62 ? 84 GLY E CA 1 ATOM 5357 C C . GLY E 2 84 ? 100.004 49.098 24.706 1.00 66.16 ? 84 GLY E C 1 ATOM 5358 O O . GLY E 2 84 ? 99.875 50.200 24.161 1.00 66.94 ? 84 GLY E O 1 ATOM 5359 N N . VAL E 2 85 ? 101.170 48.463 24.792 1.00 63.65 ? 85 VAL E N 1 ATOM 5360 C CA . VAL E 2 85 ? 102.389 49.039 24.241 1.00 61.32 ? 85 VAL E CA 1 ATOM 5361 C C . VAL E 2 85 ? 102.233 49.311 22.752 1.00 61.77 ? 85 VAL E C 1 ATOM 5362 O O . VAL E 2 85 ? 103.113 49.895 22.124 1.00 62.27 ? 85 VAL E O 1 ATOM 5363 C CB . VAL E 2 85 ? 103.598 48.102 24.455 1.00 61.24 ? 85 VAL E CB 1 ATOM 5364 C CG1 . VAL E 2 85 ? 104.854 48.709 23.837 1.00 58.88 ? 85 VAL E CG1 1 ATOM 5365 C CG2 . VAL E 2 85 ? 103.805 47.856 25.943 1.00 59.24 ? 85 VAL E CG2 1 ATOM 5366 N N . GLY E 2 86 ? 101.108 48.894 22.184 1.00 62.32 ? 86 GLY E N 1 ATOM 5367 C CA . GLY E 2 86 ? 100.906 49.126 20.771 1.00 64.28 ? 86 GLY E CA 1 ATOM 5368 C C . GLY E 2 86 ? 99.514 48.853 20.255 1.00 65.39 ? 86 GLY E C 1 ATOM 5369 O O . GLY E 2 86 ? 99.321 48.712 19.048 1.00 64.74 ? 86 GLY E O 1 ATOM 5370 N N . GLU E 2 87 ? 98.540 48.781 21.157 1.00 67.53 ? 87 GLU E N 1 ATOM 5371 C CA . GLU E 2 87 ? 97.163 48.533 20.751 1.00 71.11 ? 87 GLU E CA 1 ATOM 5372 C C . GLU E 2 87 ? 96.723 49.703 19.879 1.00 71.25 ? 87 GLU E C 1 ATOM 5373 O O . GLU E 2 87 ? 95.596 49.763 19.399 1.00 69.65 ? 87 GLU E O 1 ATOM 5374 C CB . GLU E 2 87 ? 96.251 48.444 21.972 1.00 74.20 ? 87 GLU E CB 1 ATOM 5375 C CG . GLU E 2 87 ? 95.848 49.793 22.533 1.00 80.55 ? 87 GLU E CG 1 ATOM 5376 C CD . GLU E 2 87 ? 94.624 49.703 23.421 1.00 86.15 ? 87 GLU E CD 1 ATOM 5377 O OE1 . GLU E 2 87 ? 94.740 49.169 24.546 1.00 87.20 ? 87 GLU E OE1 1 ATOM 5378 O OE2 . GLU E 2 87 ? 93.540 50.157 22.985 1.00 88.47 ? 87 GLU E OE2 1 ATOM 5379 N N . SER E 2 88 ? 97.643 50.636 19.693 1.00 73.70 ? 88 SER E N 1 ATOM 5380 C CA . SER E 2 88 ? 97.414 51.830 18.901 1.00 74.65 ? 88 SER E CA 1 ATOM 5381 C C . SER E 2 88 ? 97.445 51.502 17.409 1.00 73.65 ? 88 SER E C 1 ATOM 5382 O O . SER E 2 88 ? 96.490 51.766 16.679 1.00 73.49 ? 88 SER E O 1 ATOM 5383 C CB . SER E 2 88 ? 98.507 52.856 19.222 1.00 77.57 ? 88 SER E CB 1 ATOM 5384 O OG . SER E 2 88 ? 98.866 52.815 20.598 1.00 79.94 ? 88 SER E OG 1 ATOM 5385 N N . PHE E 2 89 ? 98.559 50.915 16.978 1.00 72.94 ? 89 PHE E N 1 ATOM 5386 C CA . PHE E 2 89 ? 98.787 50.553 15.581 1.00 69.95 ? 89 PHE E CA 1 ATOM 5387 C C . PHE E 2 89 ? 98.381 49.123 15.224 1.00 66.98 ? 89 PHE E C 1 ATOM 5388 O O . PHE E 2 89 ? 98.371 48.754 14.050 1.00 66.30 ? 89 PHE E O 1 ATOM 5389 C CB . PHE E 2 89 ? 100.264 50.759 15.241 1.00 69.14 ? 89 PHE E CB 1 ATOM 5390 C CG . PHE E 2 89 ? 101.197 49.887 16.038 1.00 66.73 ? 89 PHE E CG 1 ATOM 5391 C CD1 . PHE E 2 89 ? 101.758 48.749 15.473 1.00 66.16 ? 89 PHE E CD1 1 ATOM 5392 C CD2 . PHE E 2 89 ? 101.515 50.205 17.353 1.00 64.59 ? 89 PHE E CD2 1 ATOM 5393 C CE1 . PHE E 2 89 ? 102.623 47.943 16.204 1.00 63.89 ? 89 PHE E CE1 1 ATOM 5394 C CE2 . PHE E 2 89 ? 102.375 49.406 18.088 1.00 62.46 ? 89 PHE E CE2 1 ATOM 5395 C CZ . PHE E 2 89 ? 102.931 48.275 17.515 1.00 62.79 ? 89 PHE E CZ 1 ATOM 5396 N N . THR E 2 90 ? 98.066 48.314 16.229 1.00 63.14 ? 90 THR E N 1 ATOM 5397 C CA . THR E 2 90 ? 97.654 46.946 15.965 1.00 59.26 ? 90 THR E CA 1 ATOM 5398 C C . THR E 2 90 ? 96.181 46.761 16.280 1.00 58.44 ? 90 THR E C 1 ATOM 5399 O O . THR E 2 90 ? 95.334 46.828 15.394 1.00 57.45 ? 90 THR E O 1 ATOM 5400 C CB . THR E 2 90 ? 98.462 45.910 16.794 1.00 57.53 ? 90 THR E CB 1 ATOM 5401 O OG1 . THR E 2 90 ? 98.362 46.214 18.192 1.00 53.18 ? 90 THR E OG1 1 ATOM 5402 C CG2 . THR E 2 90 ? 99.913 45.895 16.361 1.00 55.20 ? 90 THR E CG2 1 ATOM 5403 N N . VAL E 2 91 ? 95.886 46.540 17.553 1.00 58.73 ? 91 VAL E N 1 ATOM 5404 C CA . VAL E 2 91 ? 94.523 46.319 18.008 1.00 61.19 ? 91 VAL E CA 1 ATOM 5405 C C . VAL E 2 91 ? 93.538 47.418 17.599 1.00 64.32 ? 91 VAL E C 1 ATOM 5406 O O . VAL E 2 91 ? 92.360 47.347 17.935 1.00 66.99 ? 91 VAL E O 1 ATOM 5407 C CB . VAL E 2 91 ? 94.489 46.149 19.548 1.00 60.22 ? 91 VAL E CB 1 ATOM 5408 C CG1 . VAL E 2 91 ? 93.139 45.602 19.996 1.00 56.34 ? 91 VAL E CG1 1 ATOM 5409 C CG2 . VAL E 2 91 ? 95.623 45.219 19.990 1.00 61.52 ? 91 VAL E CG2 1 ATOM 5410 N N . GLN E 2 92 ? 94.004 48.432 16.877 1.00 66.79 ? 92 GLN E N 1 ATOM 5411 C CA . GLN E 2 92 ? 93.109 49.501 16.448 1.00 68.97 ? 92 GLN E CA 1 ATOM 5412 C C . GLN E 2 92 ? 93.400 49.970 15.042 1.00 66.69 ? 92 GLN E C 1 ATOM 5413 O O . GLN E 2 92 ? 92.735 50.866 14.532 1.00 66.75 ? 92 GLN E O 1 ATOM 5414 C CB . GLN E 2 92 ? 93.183 50.695 17.398 1.00 77.76 ? 92 GLN E CB 1 ATOM 5415 C CG . GLN E 2 92 ? 92.702 50.391 18.806 1.00 92.29 ? 92 GLN E CG 1 ATOM 5416 C CD . GLN E 2 92 ? 92.399 51.648 19.604 1.00 101.98 ? 92 GLN E CD 1 ATOM 5417 O OE1 . GLN E 2 92 ? 93.207 52.584 19.650 1.00 106.03 ? 92 GLN E OE1 1 ATOM 5418 N NE2 . GLN E 2 92 ? 91.231 51.673 20.246 1.00 105.57 ? 92 GLN E NE2 1 ATOM 5419 N N . ARG E 2 93 ? 94.405 49.372 14.417 1.00 65.79 ? 93 ARG E N 1 ATOM 5420 C CA . ARG E 2 93 ? 94.759 49.725 13.048 1.00 63.16 ? 93 ARG E CA 1 ATOM 5421 C C . ARG E 2 93 ? 93.484 49.571 12.215 1.00 60.85 ? 93 ARG E C 1 ATOM 5422 O O . ARG E 2 93 ? 92.494 49.005 12.687 1.00 57.89 ? 93 ARG E O 1 ATOM 5423 C CB . ARG E 2 93 ? 95.852 48.776 12.534 1.00 62.16 ? 93 ARG E CB 1 ATOM 5424 C CG . ARG E 2 93 ? 96.318 48.996 11.096 1.00 58.40 ? 93 ARG E CG 1 ATOM 5425 C CD . ARG E 2 93 ? 97.011 47.736 10.594 1.00 58.39 ? 93 ARG E CD 1 ATOM 5426 N NE . ARG E 2 93 ? 97.415 47.801 9.193 1.00 56.85 ? 93 ARG E NE 1 ATOM 5427 C CZ . ARG E 2 93 ? 98.452 48.497 8.747 1.00 58.20 ? 93 ARG E CZ 1 ATOM 5428 N NH1 . ARG E 2 93 ? 99.194 49.193 9.600 1.00 57.28 ? 93 ARG E NH1 1 ATOM 5429 N NH2 . ARG E 2 93 ? 98.752 48.487 7.453 1.00 57.18 ? 93 ARG E NH2 1 ATOM 5430 N N . ARG E 2 94 ? 93.511 50.081 10.988 1.00 58.42 ? 94 ARG E N 1 ATOM 5431 C CA . ARG E 2 94 ? 92.367 49.994 10.091 1.00 55.99 ? 94 ARG E CA 1 ATOM 5432 C C . ARG E 2 94 ? 92.654 50.574 8.713 1.00 53.46 ? 94 ARG E C 1 ATOM 5433 O O . ARG E 2 94 ? 92.858 51.771 8.568 1.00 54.48 ? 94 ARG E O 1 ATOM 5434 C CB . ARG E 2 94 ? 91.160 50.707 10.704 1.00 55.18 ? 94 ARG E CB 1 ATOM 5435 C CG . ARG E 2 94 ? 90.270 49.801 11.530 1.00 54.16 ? 94 ARG E CG 1 ATOM 5436 C CD . ARG E 2 94 ? 89.339 50.599 12.403 1.00 55.38 ? 94 ARG E CD 1 ATOM 5437 N NE . ARG E 2 94 ? 88.506 49.760 13.260 1.00 55.07 ? 94 ARG E NE 1 ATOM 5438 C CZ . ARG E 2 94 ? 88.962 48.790 14.048 1.00 54.63 ? 94 ARG E CZ 1 ATOM 5439 N NH1 . ARG E 2 94 ? 90.263 48.509 14.095 1.00 53.22 ? 94 ARG E NH1 1 ATOM 5440 N NH2 . ARG E 2 94 ? 88.114 48.116 14.814 1.00 52.64 ? 94 ARG E NH2 1 ATOM 5441 N N . VAL E 2 95 ? 92.688 49.715 7.705 1.00 51.82 ? 95 VAL E N 1 ATOM 5442 C CA . VAL E 2 95 ? 92.916 50.162 6.339 1.00 52.05 ? 95 VAL E CA 1 ATOM 5443 C C . VAL E 2 95 ? 91.561 50.037 5.643 1.00 53.86 ? 95 VAL E C 1 ATOM 5444 O O . VAL E 2 95 ? 90.719 49.234 6.052 1.00 54.45 ? 95 VAL E O 1 ATOM 5445 C CB . VAL E 2 95 ? 93.975 49.290 5.631 1.00 50.19 ? 95 VAL E CB 1 ATOM 5446 C CG1 . VAL E 2 95 ? 94.095 49.696 4.166 1.00 47.31 ? 95 VAL E CG1 1 ATOM 5447 C CG2 . VAL E 2 95 ? 95.314 49.436 6.343 1.00 45.15 ? 95 VAL E CG2 1 ATOM 5448 N N . GLU E 2 96 ? 91.332 50.826 4.603 1.00 53.45 ? 96 GLU E N 1 ATOM 5449 C CA . GLU E 2 96 ? 90.041 50.770 3.949 1.00 56.22 ? 96 GLU E CA 1 ATOM 5450 C C . GLU E 2 96 ? 90.043 49.927 2.689 1.00 54.95 ? 96 GLU E C 1 ATOM 5451 O O . GLU E 2 96 ? 90.904 50.077 1.820 1.00 55.20 ? 96 GLU E O 1 ATOM 5452 C CB . GLU E 2 96 ? 89.549 52.187 3.635 1.00 63.22 ? 96 GLU E CB 1 ATOM 5453 C CG . GLU E 2 96 ? 88.040 52.296 3.382 1.00 71.86 ? 96 GLU E CG 1 ATOM 5454 C CD . GLU E 2 96 ? 87.580 53.736 3.167 1.00 78.33 ? 96 GLU E CD 1 ATOM 5455 O OE1 . GLU E 2 96 ? 87.911 54.323 2.111 1.00 79.28 ? 96 GLU E OE1 1 ATOM 5456 O OE2 . GLU E 2 96 ? 86.894 54.284 4.060 1.00 81.05 ? 96 GLU E OE2 1 ATOM 5457 N N . PRO E 2 97 ? 89.067 49.014 2.579 1.00 53.08 ? 97 PRO E N 1 ATOM 5458 C CA . PRO E 2 97 ? 88.947 48.135 1.416 1.00 48.87 ? 97 PRO E CA 1 ATOM 5459 C C . PRO E 2 97 ? 88.904 48.942 0.135 1.00 44.94 ? 97 PRO E C 1 ATOM 5460 O O . PRO E 2 97 ? 88.297 49.997 0.084 1.00 44.27 ? 97 PRO E O 1 ATOM 5461 C CB . PRO E 2 97 ? 87.622 47.418 1.660 1.00 48.75 ? 97 PRO E CB 1 ATOM 5462 C CG . PRO E 2 97 ? 87.545 47.349 3.148 1.00 52.08 ? 97 PRO E CG 1 ATOM 5463 C CD . PRO E 2 97 ? 88.026 48.713 3.580 1.00 52.89 ? 97 PRO E CD 1 ATOM 5464 N N . LYS E 2 98 ? 89.572 48.463 -0.896 1.00 43.52 ? 98 LYS E N 1 ATOM 5465 C CA . LYS E 2 98 ? 89.515 49.151 -2.166 1.00 46.43 ? 98 LYS E CA 1 ATOM 5466 C C . LYS E 2 98 ? 88.775 48.137 -3.025 1.00 43.60 ? 98 LYS E C 1 ATOM 5467 O O . LYS E 2 98 ? 89.370 47.244 -3.615 1.00 46.00 ? 98 LYS E O 1 ATOM 5468 C CB . LYS E 2 98 ? 90.921 49.426 -2.700 1.00 53.25 ? 98 LYS E CB 1 ATOM 5469 C CG . LYS E 2 98 ? 90.992 50.621 -3.657 1.00 63.42 ? 98 LYS E CG 1 ATOM 5470 C CD . LYS E 2 98 ? 92.440 51.057 -3.925 1.00 73.32 ? 98 LYS E CD 1 ATOM 5471 C CE . LYS E 2 98 ? 92.523 52.445 -4.588 1.00 79.67 ? 98 LYS E CE 1 ATOM 5472 N NZ . LYS E 2 98 ? 92.051 53.583 -3.715 1.00 82.96 ? 98 LYS E NZ 1 ATOM 5473 N N . VAL E 2 99 ? 87.459 48.266 -3.061 1.00 38.96 ? 99 VAL E N 1 ATOM 5474 C CA . VAL E 2 99 ? 86.626 47.340 -3.801 1.00 34.63 ? 99 VAL E CA 1 ATOM 5475 C C . VAL E 2 99 ? 86.498 47.651 -5.282 1.00 35.55 ? 99 VAL E C 1 ATOM 5476 O O . VAL E 2 99 ? 86.312 48.801 -5.666 1.00 38.68 ? 99 VAL E O 1 ATOM 5477 C CB . VAL E 2 99 ? 85.243 47.301 -3.180 1.00 30.96 ? 99 VAL E CB 1 ATOM 5478 C CG1 . VAL E 2 99 ? 84.390 46.260 -3.862 1.00 31.02 ? 99 VAL E CG1 1 ATOM 5479 C CG2 . VAL E 2 99 ? 85.377 47.014 -1.697 1.00 30.90 ? 99 VAL E CG2 1 ATOM 5480 N N . THR E 2 100 ? 86.595 46.609 -6.105 1.00 34.65 ? 100 THR E N 1 ATOM 5481 C CA . THR E 2 100 ? 86.492 46.720 -7.563 1.00 34.38 ? 100 THR E CA 1 ATOM 5482 C C . THR E 2 100 ? 85.695 45.544 -8.135 1.00 36.64 ? 100 THR E C 1 ATOM 5483 O O . THR E 2 100 ? 85.647 44.476 -7.535 1.00 40.44 ? 100 THR E O 1 ATOM 5484 C CB . THR E 2 100 ? 87.897 46.739 -8.235 1.00 31.18 ? 100 THR E CB 1 ATOM 5485 O OG1 . THR E 2 100 ? 87.861 45.991 -9.458 1.00 25.08 ? 100 THR E OG1 1 ATOM 5486 C CG2 . THR E 2 100 ? 88.951 46.143 -7.311 1.00 29.29 ? 100 THR E CG2 1 ATOM 5487 N N . VAL E 2 101 ? 85.075 45.735 -9.293 1.00 35.62 ? 101 VAL E N 1 ATOM 5488 C CA . VAL E 2 101 ? 84.304 44.669 -9.902 1.00 36.34 ? 101 VAL E CA 1 ATOM 5489 C C . VAL E 2 101 ? 84.638 44.511 -11.371 1.00 44.13 ? 101 VAL E C 1 ATOM 5490 O O . VAL E 2 101 ? 84.677 45.492 -12.113 1.00 47.32 ? 101 VAL E O 1 ATOM 5491 C CB . VAL E 2 101 ? 82.805 44.927 -9.750 1.00 32.86 ? 101 VAL E CB 1 ATOM 5492 C CG1 . VAL E 2 101 ? 82.018 44.097 -10.759 1.00 28.61 ? 101 VAL E CG1 1 ATOM 5493 C CG2 . VAL E 2 101 ? 82.381 44.578 -8.335 1.00 32.03 ? 101 VAL E CG2 1 ATOM 5494 N N . TYR E 2 102 ? 84.874 43.265 -11.780 1.00 49.46 ? 102 TYR E N 1 ATOM 5495 C CA . TYR E 2 102 ? 85.218 42.932 -13.163 1.00 54.79 ? 102 TYR E CA 1 ATOM 5496 C C . TYR E 2 102 ? 84.862 41.493 -13.477 1.00 59.14 ? 102 TYR E C 1 ATOM 5497 O O . TYR E 2 102 ? 84.989 40.623 -12.620 1.00 62.20 ? 102 TYR E O 1 ATOM 5498 C CB . TYR E 2 102 ? 86.721 43.087 -13.406 1.00 55.52 ? 102 TYR E CB 1 ATOM 5499 C CG . TYR E 2 102 ? 87.598 42.171 -12.561 1.00 55.61 ? 102 TYR E CG 1 ATOM 5500 C CD1 . TYR E 2 102 ? 87.954 42.524 -11.255 1.00 58.93 ? 102 TYR E CD1 1 ATOM 5501 C CD2 . TYR E 2 102 ? 88.098 40.970 -13.074 1.00 53.43 ? 102 TYR E CD2 1 ATOM 5502 C CE1 . TYR E 2 102 ? 88.794 41.711 -10.483 1.00 57.71 ? 102 TYR E CE1 1 ATOM 5503 C CE2 . TYR E 2 102 ? 88.933 40.150 -12.311 1.00 53.30 ? 102 TYR E CE2 1 ATOM 5504 C CZ . TYR E 2 102 ? 89.280 40.531 -11.018 1.00 56.43 ? 102 TYR E CZ 1 ATOM 5505 O OH . TYR E 2 102 ? 90.136 39.760 -10.263 1.00 56.88 ? 102 TYR E OH 1 ATOM 5506 N N . PRO E 2 103 ? 84.403 41.216 -14.707 1.00 62.10 ? 103 PRO E N 1 ATOM 5507 C CA . PRO E 2 103 ? 84.077 39.823 -15.002 1.00 66.47 ? 103 PRO E CA 1 ATOM 5508 C C . PRO E 2 103 ? 85.376 39.084 -15.302 1.00 72.29 ? 103 PRO E C 1 ATOM 5509 O O . PRO E 2 103 ? 86.459 39.659 -15.228 1.00 73.08 ? 103 PRO E O 1 ATOM 5510 C CB . PRO E 2 103 ? 83.184 39.929 -16.232 1.00 61.83 ? 103 PRO E CB 1 ATOM 5511 C CG . PRO E 2 103 ? 82.565 41.249 -16.089 1.00 60.67 ? 103 PRO E CG 1 ATOM 5512 C CD . PRO E 2 103 ? 83.732 42.102 -15.668 1.00 61.72 ? 103 PRO E CD 1 ATOM 5513 N N . ALA E 2 104 ? 85.268 37.808 -15.630 1.00 78.74 ? 104 ALA E N 1 ATOM 5514 C CA . ALA E 2 104 ? 86.437 37.022 -15.961 1.00 89.18 ? 104 ALA E CA 1 ATOM 5515 C C . ALA E 2 104 ? 86.048 36.270 -17.216 1.00 98.03 ? 104 ALA E C 1 ATOM 5516 O O . ALA E 2 104 ? 84.930 35.763 -17.299 1.00 101.13 ? 104 ALA E O 1 ATOM 5517 C CB . ALA E 2 104 ? 86.753 36.064 -14.839 1.00 88.27 ? 104 ALA E CB 1 ATOM 5518 N N . ARG E 2 105 ? 86.954 36.209 -18.193 1.00 108.08 ? 105 ARG E N 1 ATOM 5519 C CA . ARG E 2 105 ? 86.686 35.522 -19.461 1.00 117.96 ? 105 ARG E CA 1 ATOM 5520 C C . ARG E 2 105 ? 85.215 35.668 -19.867 1.00 122.97 ? 105 ARG E C 1 ATOM 5521 O O . ARG E 2 105 ? 84.529 34.682 -20.147 1.00 123.54 ? 105 ARG E O 1 ATOM 5522 C CB . ARG E 2 105 ? 87.081 34.035 -19.355 1.00 119.79 ? 105 ARG E CB 1 ATOM 5523 C CG . ARG E 2 105 ? 86.549 33.298 -18.115 1.00 122.44 ? 105 ARG E CG 1 ATOM 5524 C CD . ARG E 2 105 ? 85.184 32.651 -18.348 1.00 124.14 ? 105 ARG E CD 1 ATOM 5525 N NE . ARG E 2 105 ? 85.284 31.408 -19.110 1.00 127.04 ? 105 ARG E NE 1 ATOM 5526 C CZ . ARG E 2 105 ? 84.242 30.699 -19.534 1.00 126.93 ? 105 ARG E CZ 1 ATOM 5527 N NH1 . ARG E 2 105 ? 83.008 31.110 -19.276 1.00 127.76 ? 105 ARG E NH1 1 ATOM 5528 N NH2 . ARG E 2 105 ? 84.434 29.572 -20.209 1.00 124.60 ? 105 ARG E NH2 1 ATOM 5529 N N . THR E 2 106 ? 84.746 36.916 -19.903 1.00 128.78 ? 106 THR E N 1 ATOM 5530 C CA . THR E 2 106 ? 83.355 37.230 -20.244 1.00 135.22 ? 106 THR E CA 1 ATOM 5531 C C . THR E 2 106 ? 83.191 37.958 -21.589 1.00 137.36 ? 106 THR E C 1 ATOM 5532 O O . THR E 2 106 ? 82.295 38.793 -21.762 1.00 137.30 ? 106 THR E O 1 ATOM 5533 C CB . THR E 2 106 ? 82.709 38.084 -19.118 1.00 137.30 ? 106 THR E CB 1 ATOM 5534 O OG1 . THR E 2 106 ? 82.836 37.393 -17.867 1.00 138.48 ? 106 THR E OG1 1 ATOM 5535 C CG2 . THR E 2 106 ? 81.226 38.348 -19.405 1.00 138.07 ? 106 THR E CG2 1 ATOM 5536 N N . GLN E 2 107 ? 84.053 37.634 -22.546 1.00 139.57 ? 107 GLN E N 1 ATOM 5537 C CA . GLN E 2 107 ? 83.970 38.253 -23.861 1.00 141.40 ? 107 GLN E CA 1 ATOM 5538 C C . GLN E 2 107 ? 82.783 37.649 -24.606 1.00 143.11 ? 107 GLN E C 1 ATOM 5539 O O . GLN E 2 107 ? 82.674 37.763 -25.830 1.00 143.55 ? 107 GLN E O 1 ATOM 5540 C CB . GLN E 2 107 ? 85.267 38.018 -24.639 1.00 141.19 ? 107 GLN E CB 1 ATOM 5541 C CG . GLN E 2 107 ? 86.517 38.367 -23.848 1.00 141.05 ? 107 GLN E CG 1 ATOM 5542 C CD . GLN E 2 107 ? 86.293 39.527 -22.895 1.00 140.43 ? 107 GLN E CD 1 ATOM 5543 O OE1 . GLN E 2 107 ? 85.863 40.607 -23.300 1.00 141.39 ? 107 GLN E OE1 1 ATOM 5544 N NE2 . GLN E 2 107 ? 86.582 39.306 -21.618 1.00 138.73 ? 107 GLN E NE2 1 ATOM 5545 N N . THR E 2 108 ? 81.896 37.007 -23.848 1.00 144.26 ? 108 THR E N 1 ATOM 5546 C CA . THR E 2 108 ? 80.701 36.376 -24.400 1.00 144.28 ? 108 THR E CA 1 ATOM 5547 C C . THR E 2 108 ? 79.493 36.614 -23.496 1.00 143.17 ? 108 THR E C 1 ATOM 5548 O O . THR E 2 108 ? 78.939 35.665 -22.939 1.00 143.74 ? 108 THR E O 1 ATOM 5549 C CB . THR E 2 108 ? 80.877 34.842 -24.553 1.00 144.68 ? 108 THR E CB 1 ATOM 5550 O OG1 . THR E 2 108 ? 82.134 34.558 -25.179 1.00 145.85 ? 108 THR E OG1 1 ATOM 5551 C CG2 . THR E 2 108 ? 79.749 34.257 -25.410 1.00 143.70 ? 108 THR E CG2 1 ATOM 5552 N N . LEU E 2 109 ? 79.095 37.874 -23.333 1.00 140.91 ? 109 LEU E N 1 ATOM 5553 C CA . LEU E 2 109 ? 77.928 38.175 -22.510 1.00 137.26 ? 109 LEU E CA 1 ATOM 5554 C C . LEU E 2 109 ? 76.728 37.641 -23.297 1.00 133.79 ? 109 LEU E C 1 ATOM 5555 O O . LEU E 2 109 ? 76.801 37.532 -24.521 1.00 133.27 ? 109 LEU E O 1 ATOM 5556 C CB . LEU E 2 109 ? 77.818 39.690 -22.250 1.00 138.25 ? 109 LEU E CB 1 ATOM 5557 C CG . LEU E 2 109 ? 77.474 40.750 -23.311 1.00 139.22 ? 109 LEU E CG 1 ATOM 5558 C CD1 . LEU E 2 109 ? 78.207 40.458 -24.614 1.00 139.53 ? 109 LEU E CD1 1 ATOM 5559 C CD2 . LEU E 2 109 ? 75.968 40.790 -23.528 1.00 138.83 ? 109 LEU E CD2 1 ATOM 5560 N N . GLN E 2 110 ? 75.654 37.286 -22.590 1.00 129.27 ? 110 GLN E N 1 ATOM 5561 C CA . GLN E 2 110 ? 74.426 36.723 -23.176 1.00 124.10 ? 110 GLN E CA 1 ATOM 5562 C C . GLN E 2 110 ? 74.381 35.204 -22.953 1.00 118.51 ? 110 GLN E C 1 ATOM 5563 O O . GLN E 2 110 ? 73.409 34.532 -23.317 1.00 117.64 ? 110 GLN E O 1 ATOM 5564 C CB . GLN E 2 110 ? 74.319 37.040 -24.673 1.00 127.78 ? 110 GLN E CB 1 ATOM 5565 C CG . GLN E 2 110 ? 74.170 38.530 -24.981 1.00 133.03 ? 110 GLN E CG 1 ATOM 5566 C CD . GLN E 2 110 ? 74.343 38.853 -26.458 1.00 136.54 ? 110 GLN E CD 1 ATOM 5567 O OE1 . GLN E 2 110 ? 73.575 38.386 -27.303 1.00 137.81 ? 110 GLN E OE1 1 ATOM 5568 N NE2 . GLN E 2 110 ? 75.356 39.658 -26.777 1.00 137.93 ? 110 GLN E NE2 1 ATOM 5569 N N . HIS E 2 111 ? 75.453 34.680 -22.357 1.00 111.06 ? 111 HIS E N 1 ATOM 5570 C CA . HIS E 2 111 ? 75.575 33.262 -22.014 1.00 100.85 ? 111 HIS E CA 1 ATOM 5571 C C . HIS E 2 111 ? 76.319 33.222 -20.668 1.00 92.75 ? 111 HIS E C 1 ATOM 5572 O O . HIS E 2 111 ? 77.149 34.091 -20.395 1.00 91.68 ? 111 HIS E O 1 ATOM 5573 C CB . HIS E 2 111 ? 76.294 32.484 -23.148 1.00 102.91 ? 111 HIS E CB 1 ATOM 5574 C CG . HIS E 2 111 ? 77.723 32.115 -22.868 1.00 104.24 ? 111 HIS E CG 1 ATOM 5575 N ND1 . HIS E 2 111 ? 78.731 33.048 -22.740 1.00 105.16 ? 111 HIS E ND1 1 ATOM 5576 C CD2 . HIS E 2 111 ? 78.321 30.903 -22.764 1.00 103.53 ? 111 HIS E CD2 1 ATOM 5577 C CE1 . HIS E 2 111 ? 79.886 32.427 -22.573 1.00 104.45 ? 111 HIS E CE1 1 ATOM 5578 N NE2 . HIS E 2 111 ? 79.665 31.125 -22.584 1.00 102.85 ? 111 HIS E NE2 1 ATOM 5579 N N . HIS E 2 112 ? 75.979 32.247 -19.825 1.00 81.99 ? 112 HIS E N 1 ATOM 5580 C CA . HIS E 2 112 ? 76.552 32.088 -18.481 1.00 70.28 ? 112 HIS E CA 1 ATOM 5581 C C . HIS E 2 112 ? 77.786 32.922 -18.120 1.00 62.96 ? 112 HIS E C 1 ATOM 5582 O O . HIS E 2 112 ? 78.576 33.311 -18.971 1.00 58.33 ? 112 HIS E O 1 ATOM 5583 C CB . HIS E 2 112 ? 76.855 30.611 -18.205 1.00 69.63 ? 112 HIS E CB 1 ATOM 5584 C CG . HIS E 2 112 ? 78.309 30.268 -18.287 1.00 66.04 ? 112 HIS E CG 1 ATOM 5585 N ND1 . HIS E 2 112 ? 78.872 29.671 -19.395 1.00 63.62 ? 112 HIS E ND1 1 ATOM 5586 C CD2 . HIS E 2 112 ? 79.324 30.480 -17.415 1.00 64.00 ? 112 HIS E CD2 1 ATOM 5587 C CE1 . HIS E 2 112 ? 80.171 29.533 -19.202 1.00 64.85 ? 112 HIS E CE1 1 ATOM 5588 N NE2 . HIS E 2 112 ? 80.471 30.016 -18.009 1.00 64.76 ? 112 HIS E NE2 1 ATOM 5589 N N . ASN E 2 113 ? 77.973 33.166 -16.833 1.00 57.67 ? 113 ASN E N 1 ATOM 5590 C CA . ASN E 2 113 ? 79.115 33.954 -16.437 1.00 53.66 ? 113 ASN E CA 1 ATOM 5591 C C . ASN E 2 113 ? 79.642 33.804 -15.028 1.00 51.11 ? 113 ASN E C 1 ATOM 5592 O O . ASN E 2 113 ? 79.352 32.837 -14.328 1.00 54.69 ? 113 ASN E O 1 ATOM 5593 C CB . ASN E 2 113 ? 78.833 35.415 -16.677 1.00 56.41 ? 113 ASN E CB 1 ATOM 5594 C CG . ASN E 2 113 ? 79.951 36.077 -17.394 1.00 60.18 ? 113 ASN E CG 1 ATOM 5595 O OD1 . ASN E 2 113 ? 79.995 36.074 -18.624 1.00 63.82 ? 113 ASN E OD1 1 ATOM 5596 N ND2 . ASN E 2 113 ? 80.894 36.625 -16.639 1.00 60.43 ? 113 ASN E ND2 1 ATOM 5597 N N . LEU E 2 114 ? 80.435 34.786 -14.622 1.00 44.11 ? 114 LEU E N 1 ATOM 5598 C CA . LEU E 2 114 ? 81.049 34.782 -13.308 1.00 39.54 ? 114 LEU E CA 1 ATOM 5599 C C . LEU E 2 114 ? 81.695 36.142 -13.089 1.00 39.09 ? 114 LEU E C 1 ATOM 5600 O O . LEU E 2 114 ? 82.761 36.419 -13.654 1.00 39.15 ? 114 LEU E O 1 ATOM 5601 C CB . LEU E 2 114 ? 82.123 33.688 -13.234 1.00 34.88 ? 114 LEU E CB 1 ATOM 5602 C CG . LEU E 2 114 ? 82.923 33.573 -11.933 1.00 31.17 ? 114 LEU E CG 1 ATOM 5603 C CD1 . LEU E 2 114 ? 82.085 32.893 -10.889 1.00 31.55 ? 114 LEU E CD1 1 ATOM 5604 C CD2 . LEU E 2 114 ? 84.180 32.791 -12.160 1.00 27.03 ? 114 LEU E CD2 1 ATOM 5605 N N . LEU E 2 115 ? 81.040 36.979 -12.277 1.00 34.93 ? 115 LEU E N 1 ATOM 5606 C CA . LEU E 2 115 ? 81.510 38.327 -11.947 1.00 29.33 ? 115 LEU E CA 1 ATOM 5607 C C . LEU E 2 115 ? 82.401 38.284 -10.732 1.00 25.41 ? 115 LEU E C 1 ATOM 5608 O O . LEU E 2 115 ? 82.145 37.542 -9.800 1.00 28.14 ? 115 LEU E O 1 ATOM 5609 C CB . LEU E 2 115 ? 80.335 39.242 -11.623 1.00 32.98 ? 115 LEU E CB 1 ATOM 5610 C CG . LEU E 2 115 ? 79.430 39.746 -12.736 1.00 36.69 ? 115 LEU E CG 1 ATOM 5611 C CD1 . LEU E 2 115 ? 78.941 38.584 -13.595 1.00 40.97 ? 115 LEU E CD1 1 ATOM 5612 C CD2 . LEU E 2 115 ? 78.263 40.492 -12.087 1.00 37.63 ? 115 LEU E CD2 1 ATOM 5613 N N . VAL E 2 116 ? 83.426 39.112 -10.704 1.00 22.95 ? 116 VAL E N 1 ATOM 5614 C CA . VAL E 2 116 ? 84.320 39.085 -9.566 1.00 23.53 ? 116 VAL E CA 1 ATOM 5615 C C . VAL E 2 116 ? 84.371 40.367 -8.773 1.00 23.19 ? 116 VAL E C 1 ATOM 5616 O O . VAL E 2 116 ? 84.642 41.426 -9.322 1.00 24.22 ? 116 VAL E O 1 ATOM 5617 C CB . VAL E 2 116 ? 85.755 38.751 -10.012 1.00 22.02 ? 116 VAL E CB 1 ATOM 5618 C CG1 . VAL E 2 116 ? 86.707 38.821 -8.836 1.00 18.49 ? 116 VAL E CG1 1 ATOM 5619 C CG2 . VAL E 2 116 ? 85.783 37.385 -10.637 1.00 24.00 ? 116 VAL E CG2 1 ATOM 5620 N N . CYS E 2 117 ? 84.103 40.276 -7.479 1.00 24.25 ? 117 CYS E N 1 ATOM 5621 C CA . CYS E 2 117 ? 84.204 41.454 -6.642 1.00 27.58 ? 117 CYS E CA 1 ATOM 5622 C C . CYS E 2 117 ? 85.547 41.258 -5.964 1.00 27.67 ? 117 CYS E C 1 ATOM 5623 O O . CYS E 2 117 ? 85.724 40.327 -5.186 1.00 26.73 ? 117 CYS E O 1 ATOM 5624 C CB . CYS E 2 117 ? 83.082 41.518 -5.603 1.00 31.35 ? 117 CYS E CB 1 ATOM 5625 S SG . CYS E 2 117 ? 83.092 43.083 -4.663 1.00 38.60 ? 117 CYS E SG 1 ATOM 5626 N N . SER E 2 118 ? 86.498 42.123 -6.281 1.00 29.46 ? 118 SER E N 1 ATOM 5627 C CA . SER E 2 118 ? 87.835 42.025 -5.719 1.00 33.76 ? 118 SER E CA 1 ATOM 5628 C C . SER E 2 118 ? 88.100 43.021 -4.571 1.00 32.48 ? 118 SER E C 1 ATOM 5629 O O . SER E 2 118 ? 88.597 44.117 -4.790 1.00 35.32 ? 118 SER E O 1 ATOM 5630 C CB . SER E 2 118 ? 88.842 42.218 -6.854 1.00 37.18 ? 118 SER E CB 1 ATOM 5631 O OG . SER E 2 118 ? 90.158 41.900 -6.440 1.00 47.85 ? 118 SER E OG 1 ATOM 5632 N N . VAL E 2 119 ? 87.775 42.630 -3.347 1.00 31.46 ? 119 VAL E N 1 ATOM 5633 C CA . VAL E 2 119 ? 87.967 43.487 -2.177 1.00 34.57 ? 119 VAL E CA 1 ATOM 5634 C C . VAL E 2 119 ? 89.409 43.416 -1.672 1.00 39.65 ? 119 VAL E C 1 ATOM 5635 O O . VAL E 2 119 ? 89.720 42.588 -0.812 1.00 42.22 ? 119 VAL E O 1 ATOM 5636 C CB . VAL E 2 119 ? 87.032 43.042 -1.033 1.00 32.21 ? 119 VAL E CB 1 ATOM 5637 C CG1 . VAL E 2 119 ? 87.205 43.940 0.167 1.00 30.32 ? 119 VAL E CG1 1 ATOM 5638 C CG2 . VAL E 2 119 ? 85.591 43.054 -1.509 1.00 34.00 ? 119 VAL E CG2 1 ATOM 5639 N N . ASN E 2 120 ? 90.281 44.298 -2.161 1.00 42.38 ? 120 ASN E N 1 ATOM 5640 C CA . ASN E 2 120 ? 91.693 44.254 -1.756 1.00 45.32 ? 120 ASN E CA 1 ATOM 5641 C C . ASN E 2 120 ? 92.250 45.348 -0.846 1.00 46.15 ? 120 ASN E C 1 ATOM 5642 O O . ASN E 2 120 ? 91.844 46.506 -0.920 1.00 48.96 ? 120 ASN E O 1 ATOM 5643 C CB . ASN E 2 120 ? 92.564 44.199 -3.004 1.00 45.07 ? 120 ASN E CB 1 ATOM 5644 C CG . ASN E 2 120 ? 91.838 43.596 -4.176 1.00 48.28 ? 120 ASN E CG 1 ATOM 5645 O OD1 . ASN E 2 120 ? 91.312 42.488 -4.094 1.00 52.13 ? 120 ASN E OD1 1 ATOM 5646 N ND2 . ASN E 2 120 ? 91.799 44.324 -5.279 1.00 49.23 ? 120 ASN E ND2 1 ATOM 5647 N N . GLY E 2 121 ? 93.186 44.960 0.017 1.00 44.49 ? 121 GLY E N 1 ATOM 5648 C CA . GLY E 2 121 ? 93.852 45.914 0.887 1.00 43.74 ? 121 GLY E CA 1 ATOM 5649 C C . GLY E 2 121 ? 93.316 46.357 2.235 1.00 42.96 ? 121 GLY E C 1 ATOM 5650 O O . GLY E 2 121 ? 93.898 47.243 2.860 1.00 42.68 ? 121 GLY E O 1 ATOM 5651 N N . PHE E 2 122 ? 92.226 45.779 2.706 1.00 42.05 ? 122 PHE E N 1 ATOM 5652 C CA . PHE E 2 122 ? 91.714 46.201 4.004 1.00 44.98 ? 122 PHE E CA 1 ATOM 5653 C C . PHE E 2 122 ? 92.562 45.575 5.103 1.00 44.93 ? 122 PHE E C 1 ATOM 5654 O O . PHE E 2 122 ? 93.476 44.816 4.792 1.00 42.43 ? 122 PHE E O 1 ATOM 5655 C CB . PHE E 2 122 ? 90.259 45.769 4.138 1.00 46.21 ? 122 PHE E CB 1 ATOM 5656 C CG . PHE E 2 122 ? 90.027 44.317 3.842 1.00 46.25 ? 122 PHE E CG 1 ATOM 5657 C CD1 . PHE E 2 122 ? 90.057 43.370 4.864 1.00 44.31 ? 122 PHE E CD1 1 ATOM 5658 C CD2 . PHE E 2 122 ? 89.761 43.897 2.540 1.00 45.19 ? 122 PHE E CD2 1 ATOM 5659 C CE1 . PHE E 2 122 ? 89.819 42.027 4.595 1.00 43.58 ? 122 PHE E CE1 1 ATOM 5660 C CE2 . PHE E 2 122 ? 89.523 42.557 2.261 1.00 44.27 ? 122 PHE E CE2 1 ATOM 5661 C CZ . PHE E 2 122 ? 89.551 41.619 3.291 1.00 43.57 ? 122 PHE E CZ 1 ATOM 5662 N N . TYR E 2 123 ? 92.319 45.914 6.372 1.00 47.08 ? 123 TYR E N 1 ATOM 5663 C CA . TYR E 2 123 ? 93.092 45.253 7.411 1.00 51.87 ? 123 TYR E CA 1 ATOM 5664 C C . TYR E 2 123 ? 92.314 44.444 8.418 1.00 56.58 ? 123 TYR E C 1 ATOM 5665 O O . TYR E 2 123 ? 92.151 43.242 8.230 1.00 66.45 ? 123 TYR E O 1 ATOM 5666 C CB . TYR E 2 123 ? 94.018 46.157 8.215 1.00 49.21 ? 123 TYR E CB 1 ATOM 5667 C CG . TYR E 2 123 ? 94.598 45.352 9.381 1.00 50.14 ? 123 TYR E CG 1 ATOM 5668 C CD1 . TYR E 2 123 ? 94.176 45.570 10.698 1.00 50.95 ? 123 TYR E CD1 1 ATOM 5669 C CD2 . TYR E 2 123 ? 95.462 44.278 9.147 1.00 50.28 ? 123 TYR E CD2 1 ATOM 5670 C CE1 . TYR E 2 123 ? 94.588 44.735 11.744 1.00 51.47 ? 123 TYR E CE1 1 ATOM 5671 C CE2 . TYR E 2 123 ? 95.880 43.441 10.183 1.00 51.67 ? 123 TYR E CE2 1 ATOM 5672 C CZ . TYR E 2 123 ? 95.436 43.674 11.477 1.00 53.09 ? 123 TYR E CZ 1 ATOM 5673 O OH . TYR E 2 123 ? 95.831 42.836 12.497 1.00 54.74 ? 123 TYR E OH 1 ATOM 5674 N N . PRO E 2 124 ? 91.806 45.076 9.489 1.00 54.91 ? 124 PRO E N 1 ATOM 5675 C CA . PRO E 2 124 ? 91.080 44.230 10.447 1.00 55.32 ? 124 PRO E CA 1 ATOM 5676 C C . PRO E 2 124 ? 90.445 43.053 9.710 1.00 58.27 ? 124 PRO E C 1 ATOM 5677 O O . PRO E 2 124 ? 89.621 43.241 8.807 1.00 58.75 ? 124 PRO E O 1 ATOM 5678 C CB . PRO E 2 124 ? 90.068 45.186 11.054 1.00 54.15 ? 124 PRO E CB 1 ATOM 5679 C CG . PRO E 2 124 ? 90.776 46.500 10.968 1.00 55.63 ? 124 PRO E CG 1 ATOM 5680 C CD . PRO E 2 124 ? 91.354 46.472 9.583 1.00 50.52 ? 124 PRO E CD 1 ATOM 5681 N N . GLY E 2 125 ? 90.889 41.845 10.051 1.00 59.25 ? 125 GLY E N 1 ATOM 5682 C CA . GLY E 2 125 ? 90.383 40.651 9.393 1.00 59.33 ? 125 GLY E CA 1 ATOM 5683 C C . GLY E 2 125 ? 88.919 40.737 9.004 1.00 59.09 ? 125 GLY E C 1 ATOM 5684 O O . GLY E 2 125 ? 88.588 40.732 7.819 1.00 59.08 ? 125 GLY E O 1 ATOM 5685 N N . SER E 2 126 ? 88.059 40.829 10.018 1.00 57.27 ? 126 SER E N 1 ATOM 5686 C CA . SER E 2 126 ? 86.608 40.918 9.866 1.00 54.62 ? 126 SER E CA 1 ATOM 5687 C C . SER E 2 126 ? 86.119 41.768 8.675 1.00 52.47 ? 126 SER E C 1 ATOM 5688 O O . SER E 2 126 ? 86.625 42.866 8.423 1.00 52.30 ? 126 SER E O 1 ATOM 5689 C CB . SER E 2 126 ? 86.008 41.444 11.174 1.00 54.75 ? 126 SER E CB 1 ATOM 5690 O OG . SER E 2 126 ? 84.599 41.297 11.188 1.00 60.86 ? 126 SER E OG 1 ATOM 5691 N N . ILE E 2 127 ? 85.125 41.246 7.953 1.00 48.62 ? 127 ILE E N 1 ATOM 5692 C CA . ILE E 2 127 ? 84.552 41.914 6.782 1.00 42.61 ? 127 ILE E CA 1 ATOM 5693 C C . ILE E 2 127 ? 83.379 41.085 6.284 1.00 43.52 ? 127 ILE E C 1 ATOM 5694 O O . ILE E 2 127 ? 83.183 39.959 6.728 1.00 45.46 ? 127 ILE E O 1 ATOM 5695 C CB . ILE E 2 127 ? 85.575 42.001 5.637 1.00 36.61 ? 127 ILE E CB 1 ATOM 5696 C CG1 . ILE E 2 127 ? 85.030 42.831 4.484 1.00 32.13 ? 127 ILE E CG1 1 ATOM 5697 C CG2 . ILE E 2 127 ? 85.862 40.621 5.107 1.00 35.10 ? 127 ILE E CG2 1 ATOM 5698 C CD1 . ILE E 2 127 ? 85.996 42.946 3.342 1.00 28.63 ? 127 ILE E CD1 1 ATOM 5699 N N . GLU E 2 128 ? 82.598 41.645 5.369 1.00 44.49 ? 128 GLU E N 1 ATOM 5700 C CA . GLU E 2 128 ? 81.465 40.930 4.784 1.00 44.97 ? 128 GLU E CA 1 ATOM 5701 C C . GLU E 2 128 ? 81.203 41.425 3.376 1.00 40.73 ? 128 GLU E C 1 ATOM 5702 O O . GLU E 2 128 ? 81.318 42.617 3.095 1.00 42.61 ? 128 GLU E O 1 ATOM 5703 C CB . GLU E 2 128 ? 80.199 41.104 5.608 1.00 50.51 ? 128 GLU E CB 1 ATOM 5704 C CG . GLU E 2 128 ? 79.013 40.443 4.940 1.00 60.49 ? 128 GLU E CG 1 ATOM 5705 C CD . GLU E 2 128 ? 77.801 40.367 5.838 1.00 68.94 ? 128 GLU E CD 1 ATOM 5706 O OE1 . GLU E 2 128 ? 76.819 39.693 5.452 1.00 73.85 ? 128 GLU E OE1 1 ATOM 5707 O OE2 . GLU E 2 128 ? 77.832 40.981 6.928 1.00 72.13 ? 128 GLU E OE2 1 ATOM 5708 N N . VAL E 2 129 ? 80.838 40.517 2.488 1.00 33.79 ? 129 VAL E N 1 ATOM 5709 C CA . VAL E 2 129 ? 80.607 40.922 1.119 1.00 31.25 ? 129 VAL E CA 1 ATOM 5710 C C . VAL E 2 129 ? 79.333 40.302 0.588 1.00 33.18 ? 129 VAL E C 1 ATOM 5711 O O . VAL E 2 129 ? 79.191 39.080 0.574 1.00 35.31 ? 129 VAL E O 1 ATOM 5712 C CB . VAL E 2 129 ? 81.799 40.516 0.229 1.00 24.81 ? 129 VAL E CB 1 ATOM 5713 C CG1 . VAL E 2 129 ? 81.674 41.152 -1.121 1.00 24.47 ? 129 VAL E CG1 1 ATOM 5714 C CG2 . VAL E 2 129 ? 83.093 40.946 0.871 1.00 17.77 ? 129 VAL E CG2 1 ATOM 5715 N N . ARG E 2 130 ? 78.403 41.151 0.157 1.00 32.96 ? 130 ARG E N 1 ATOM 5716 C CA . ARG E 2 130 ? 77.132 40.680 -0.369 1.00 33.81 ? 130 ARG E CA 1 ATOM 5717 C C . ARG E 2 130 ? 77.013 41.068 -1.818 1.00 34.77 ? 130 ARG E C 1 ATOM 5718 O O . ARG E 2 130 ? 77.609 42.057 -2.248 1.00 33.22 ? 130 ARG E O 1 ATOM 5719 C CB . ARG E 2 130 ? 75.971 41.304 0.387 1.00 35.82 ? 130 ARG E CB 1 ATOM 5720 C CG . ARG E 2 130 ? 76.025 41.127 1.881 1.00 46.69 ? 130 ARG E CG 1 ATOM 5721 C CD . ARG E 2 130 ? 75.537 42.408 2.534 1.00 58.31 ? 130 ARG E CD 1 ATOM 5722 N NE . ARG E 2 130 ? 75.539 42.365 3.992 1.00 62.27 ? 130 ARG E NE 1 ATOM 5723 C CZ . ARG E 2 130 ? 74.768 41.560 4.713 1.00 65.80 ? 130 ARG E CZ 1 ATOM 5724 N NH1 . ARG E 2 130 ? 73.930 40.721 4.109 1.00 66.04 ? 130 ARG E NH1 1 ATOM 5725 N NH2 . ARG E 2 130 ? 74.825 41.607 6.038 1.00 66.61 ? 130 ARG E NH2 1 ATOM 5726 N N . TRP E 2 131 ? 76.245 40.276 -2.562 1.00 36.57 ? 131 TRP E N 1 ATOM 5727 C CA . TRP E 2 131 ? 75.998 40.519 -3.975 1.00 39.16 ? 131 TRP E CA 1 ATOM 5728 C C . TRP E 2 131 ? 74.546 40.868 -4.163 1.00 43.72 ? 131 TRP E C 1 ATOM 5729 O O . TRP E 2 131 ? 73.692 40.393 -3.414 1.00 48.92 ? 131 TRP E O 1 ATOM 5730 C CB . TRP E 2 131 ? 76.310 39.288 -4.810 1.00 36.55 ? 131 TRP E CB 1 ATOM 5731 C CG . TRP E 2 131 ? 77.669 39.331 -5.351 1.00 43.52 ? 131 TRP E CG 1 ATOM 5732 C CD1 . TRP E 2 131 ? 78.734 38.591 -4.948 1.00 45.36 ? 131 TRP E CD1 1 ATOM 5733 C CD2 . TRP E 2 131 ? 78.151 40.217 -6.364 1.00 47.01 ? 131 TRP E CD2 1 ATOM 5734 N NE1 . TRP E 2 131 ? 79.857 38.962 -5.645 1.00 48.82 ? 131 TRP E NE1 1 ATOM 5735 C CE2 . TRP E 2 131 ? 79.526 39.960 -6.522 1.00 48.46 ? 131 TRP E CE2 1 ATOM 5736 C CE3 . TRP E 2 131 ? 77.553 41.206 -7.154 1.00 49.58 ? 131 TRP E CE3 1 ATOM 5737 C CZ2 . TRP E 2 131 ? 80.319 40.658 -7.438 1.00 51.20 ? 131 TRP E CZ2 1 ATOM 5738 C CZ3 . TRP E 2 131 ? 78.342 41.899 -8.067 1.00 51.68 ? 131 TRP E CZ3 1 ATOM 5739 C CH2 . TRP E 2 131 ? 79.711 41.620 -8.200 1.00 50.25 ? 131 TRP E CH2 1 ATOM 5740 N N . PHE E 2 132 ? 74.261 41.705 -5.155 1.00 46.52 ? 132 PHE E N 1 ATOM 5741 C CA . PHE E 2 132 ? 72.887 42.093 -5.438 1.00 44.81 ? 132 PHE E CA 1 ATOM 5742 C C . PHE E 2 132 ? 72.616 42.216 -6.903 1.00 46.94 ? 132 PHE E C 1 ATOM 5743 O O . PHE E 2 132 ? 73.326 42.920 -7.621 1.00 44.59 ? 132 PHE E O 1 ATOM 5744 C CB . PHE E 2 132 ? 72.543 43.418 -4.782 1.00 43.77 ? 132 PHE E CB 1 ATOM 5745 C CG . PHE E 2 132 ? 72.536 43.355 -3.308 1.00 40.83 ? 132 PHE E CG 1 ATOM 5746 C CD1 . PHE E 2 132 ? 73.674 43.677 -2.587 1.00 39.58 ? 132 PHE E CD1 1 ATOM 5747 C CD2 . PHE E 2 132 ? 71.412 42.912 -2.638 1.00 38.04 ? 132 PHE E CD2 1 ATOM 5748 C CE1 . PHE E 2 132 ? 73.696 43.553 -1.211 1.00 41.13 ? 132 PHE E CE1 1 ATOM 5749 C CE2 . PHE E 2 132 ? 71.420 42.784 -1.267 1.00 41.88 ? 132 PHE E CE2 1 ATOM 5750 C CZ . PHE E 2 132 ? 72.566 43.104 -0.545 1.00 41.83 ? 132 PHE E CZ 1 ATOM 5751 N N . ARG E 2 133 ? 71.589 41.510 -7.349 1.00 50.79 ? 133 ARG E N 1 ATOM 5752 C CA . ARG E 2 133 ? 71.198 41.585 -8.736 1.00 58.17 ? 133 ARG E CA 1 ATOM 5753 C C . ARG E 2 133 ? 69.903 42.358 -8.677 1.00 61.73 ? 133 ARG E C 1 ATOM 5754 O O . ARG E 2 133 ? 68.915 41.875 -8.130 1.00 62.59 ? 133 ARG E O 1 ATOM 5755 C CB . ARG E 2 133 ? 70.955 40.202 -9.321 1.00 59.40 ? 133 ARG E CB 1 ATOM 5756 C CG . ARG E 2 133 ? 70.865 40.219 -10.832 1.00 63.25 ? 133 ARG E CG 1 ATOM 5757 C CD . ARG E 2 133 ? 70.666 38.829 -11.372 1.00 70.71 ? 133 ARG E CD 1 ATOM 5758 N NE . ARG E 2 133 ? 69.460 38.243 -10.816 1.00 78.01 ? 133 ARG E NE 1 ATOM 5759 C CZ . ARG E 2 133 ? 68.244 38.736 -11.010 1.00 82.23 ? 133 ARG E CZ 1 ATOM 5760 N NH1 . ARG E 2 133 ? 68.077 39.823 -11.752 1.00 83.28 ? 133 ARG E NH1 1 ATOM 5761 N NH2 . ARG E 2 133 ? 67.196 38.147 -10.454 1.00 87.36 ? 133 ARG E NH2 1 ATOM 5762 N N . ASN E 2 134 ? 69.916 43.570 -9.216 1.00 65.24 ? 134 ASN E N 1 ATOM 5763 C CA . ASN E 2 134 ? 68.728 44.401 -9.198 1.00 70.17 ? 134 ASN E CA 1 ATOM 5764 C C . ASN E 2 134 ? 68.195 44.470 -7.769 1.00 73.20 ? 134 ASN E C 1 ATOM 5765 O O . ASN E 2 134 ? 67.066 44.068 -7.496 1.00 75.72 ? 134 ASN E O 1 ATOM 5766 C CB . ASN E 2 134 ? 67.640 43.830 -10.124 1.00 70.66 ? 134 ASN E CB 1 ATOM 5767 C CG . ASN E 2 134 ? 68.098 43.693 -11.577 1.00 73.05 ? 134 ASN E CG 1 ATOM 5768 O OD1 . ASN E 2 134 ? 68.849 44.526 -12.098 1.00 71.21 ? 134 ASN E OD1 1 ATOM 5769 N ND2 . ASN E 2 134 ? 67.623 42.643 -12.243 1.00 75.35 ? 134 ASN E ND2 1 ATOM 5770 N N . SER E 2 135 ? 69.021 44.960 -6.853 1.00 75.62 ? 135 SER E N 1 ATOM 5771 C CA . SER E 2 135 ? 68.624 45.104 -5.455 1.00 78.36 ? 135 SER E CA 1 ATOM 5772 C C . SER E 2 135 ? 67.995 43.871 -4.814 1.00 77.56 ? 135 SER E C 1 ATOM 5773 O O . SER E 2 135 ? 67.253 43.980 -3.840 1.00 77.28 ? 135 SER E O 1 ATOM 5774 C CB . SER E 2 135 ? 67.669 46.288 -5.311 1.00 83.10 ? 135 SER E CB 1 ATOM 5775 O OG . SER E 2 135 ? 68.287 47.492 -5.743 1.00 90.07 ? 135 SER E OG 1 ATOM 5776 N N . GLN E 2 136 ? 68.286 42.704 -5.370 1.00 78.18 ? 136 GLN E N 1 ATOM 5777 C CA . GLN E 2 136 ? 67.790 41.444 -4.832 1.00 78.90 ? 136 GLN E CA 1 ATOM 5778 C C . GLN E 2 136 ? 69.050 40.786 -4.263 1.00 75.91 ? 136 GLN E C 1 ATOM 5779 O O . GLN E 2 136 ? 70.025 40.592 -4.990 1.00 77.16 ? 136 GLN E O 1 ATOM 5780 C CB . GLN E 2 136 ? 67.181 40.612 -5.965 1.00 85.43 ? 136 GLN E CB 1 ATOM 5781 C CG . GLN E 2 136 ? 66.720 39.208 -5.589 1.00 97.46 ? 136 GLN E CG 1 ATOM 5782 C CD . GLN E 2 136 ? 67.699 38.121 -6.028 1.00 104.51 ? 136 GLN E CD 1 ATOM 5783 O OE1 . GLN E 2 136 ? 68.813 38.024 -5.507 1.00 109.12 ? 136 GLN E OE1 1 ATOM 5784 N NE2 . GLN E 2 136 ? 67.284 37.299 -6.995 1.00 103.92 ? 136 GLN E NE2 1 ATOM 5785 N N . GLU E 2 137 ? 69.057 40.467 -2.970 1.00 70.77 ? 137 GLU E N 1 ATOM 5786 C CA . GLU E 2 137 ? 70.254 39.876 -2.391 1.00 65.50 ? 137 GLU E CA 1 ATOM 5787 C C . GLU E 2 137 ? 70.540 38.492 -2.899 1.00 63.12 ? 137 GLU E C 1 ATOM 5788 O O . GLU E 2 137 ? 70.040 37.508 -2.360 1.00 61.99 ? 137 GLU E O 1 ATOM 5789 C CB . GLU E 2 137 ? 70.196 39.829 -0.868 1.00 67.40 ? 137 GLU E CB 1 ATOM 5790 C CG . GLU E 2 137 ? 71.509 39.313 -0.267 1.00 71.04 ? 137 GLU E CG 1 ATOM 5791 C CD . GLU E 2 137 ? 71.640 39.558 1.233 1.00 75.45 ? 137 GLU E CD 1 ATOM 5792 O OE1 . GLU E 2 137 ? 72.726 39.273 1.791 1.00 74.74 ? 137 GLU E OE1 1 ATOM 5793 O OE2 . GLU E 2 137 ? 70.665 40.034 1.856 1.00 78.00 ? 137 GLU E OE2 1 ATOM 5794 N N . GLU E 2 138 ? 71.359 38.432 -3.944 1.00 62.70 ? 138 GLU E N 1 ATOM 5795 C CA . GLU E 2 138 ? 71.769 37.175 -4.555 1.00 59.68 ? 138 GLU E CA 1 ATOM 5796 C C . GLU E 2 138 ? 72.641 36.501 -3.517 1.00 57.18 ? 138 GLU E C 1 ATOM 5797 O O . GLU E 2 138 ? 73.668 37.042 -3.117 1.00 57.06 ? 138 GLU E O 1 ATOM 5798 C CB . GLU E 2 138 ? 72.593 37.441 -5.811 1.00 60.50 ? 138 GLU E CB 1 ATOM 5799 C CG . GLU E 2 138 ? 72.712 36.258 -6.737 1.00 64.75 ? 138 GLU E CG 1 ATOM 5800 C CD . GLU E 2 138 ? 71.558 36.180 -7.715 1.00 69.59 ? 138 GLU E CD 1 ATOM 5801 O OE1 . GLU E 2 138 ? 70.398 36.075 -7.258 1.00 71.10 ? 138 GLU E OE1 1 ATOM 5802 O OE2 . GLU E 2 138 ? 71.816 36.228 -8.941 1.00 70.10 ? 138 GLU E OE2 1 ATOM 5803 N N . LYS E 2 139 ? 72.220 35.330 -3.069 1.00 55.19 ? 139 LYS E N 1 ATOM 5804 C CA . LYS E 2 139 ? 72.956 34.584 -2.062 1.00 54.86 ? 139 LYS E CA 1 ATOM 5805 C C . LYS E 2 139 ? 73.387 33.244 -2.634 1.00 54.78 ? 139 LYS E C 1 ATOM 5806 O O . LYS E 2 139 ? 74.421 32.694 -2.257 1.00 57.99 ? 139 LYS E O 1 ATOM 5807 C CB . LYS E 2 139 ? 72.079 34.364 -0.827 1.00 52.54 ? 139 LYS E CB 1 ATOM 5808 C CG . LYS E 2 139 ? 70.586 34.511 -1.097 1.00 54.75 ? 139 LYS E CG 1 ATOM 5809 C CD . LYS E 2 139 ? 70.137 33.712 -2.321 1.00 56.92 ? 139 LYS E CD 1 ATOM 5810 C CE . LYS E 2 139 ? 69.530 34.632 -3.380 1.00 58.57 ? 139 LYS E CE 1 ATOM 5811 N NZ . LYS E 2 139 ? 69.352 33.968 -4.703 1.00 60.81 ? 139 LYS E NZ 1 ATOM 5812 N N . ALA E 2 140 ? 72.593 32.724 -3.559 1.00 51.66 ? 140 ALA E N 1 ATOM 5813 C CA . ALA E 2 140 ? 72.898 31.445 -4.167 1.00 46.99 ? 140 ALA E CA 1 ATOM 5814 C C . ALA E 2 140 ? 73.805 31.632 -5.365 1.00 43.63 ? 140 ALA E C 1 ATOM 5815 O O . ALA E 2 140 ? 73.542 32.468 -6.224 1.00 44.77 ? 140 ALA E O 1 ATOM 5816 C CB . ALA E 2 140 ? 71.614 30.761 -4.585 1.00 49.89 ? 140 ALA E CB 1 ATOM 5817 N N . GLY E 2 141 ? 74.875 30.850 -5.418 1.00 41.00 ? 141 GLY E N 1 ATOM 5818 C CA . GLY E 2 141 ? 75.796 30.944 -6.536 1.00 36.99 ? 141 GLY E CA 1 ATOM 5819 C C . GLY E 2 141 ? 76.938 31.891 -6.256 1.00 32.63 ? 141 GLY E C 1 ATOM 5820 O O . GLY E 2 141 ? 77.407 32.594 -7.145 1.00 31.71 ? 141 GLY E O 1 ATOM 5821 N N . VAL E 2 142 ? 77.396 31.899 -5.013 1.00 29.20 ? 142 VAL E N 1 ATOM 5822 C CA . VAL E 2 142 ? 78.477 32.777 -4.623 1.00 25.21 ? 142 VAL E CA 1 ATOM 5823 C C . VAL E 2 142 ? 79.738 32.041 -4.199 1.00 24.73 ? 142 VAL E C 1 ATOM 5824 O O . VAL E 2 142 ? 79.816 31.482 -3.105 1.00 21.93 ? 142 VAL E O 1 ATOM 5825 C CB . VAL E 2 142 ? 78.040 33.690 -3.477 1.00 23.50 ? 142 VAL E CB 1 ATOM 5826 C CG1 . VAL E 2 142 ? 79.150 34.641 -3.117 1.00 23.68 ? 142 VAL E CG1 1 ATOM 5827 C CG2 . VAL E 2 142 ? 76.817 34.450 -3.883 1.00 23.30 ? 142 VAL E CG2 1 ATOM 5828 N N . VAL E 2 143 ? 80.725 32.061 -5.083 1.00 23.24 ? 143 VAL E N 1 ATOM 5829 C CA . VAL E 2 143 ? 82.013 31.440 -4.840 1.00 23.03 ? 143 VAL E CA 1 ATOM 5830 C C . VAL E 2 143 ? 82.912 32.456 -4.155 1.00 22.51 ? 143 VAL E C 1 ATOM 5831 O O . VAL E 2 143 ? 83.134 33.538 -4.679 1.00 24.29 ? 143 VAL E O 1 ATOM 5832 C CB . VAL E 2 143 ? 82.655 31.046 -6.156 1.00 25.63 ? 143 VAL E CB 1 ATOM 5833 C CG1 . VAL E 2 143 ? 83.918 30.227 -5.901 1.00 24.98 ? 143 VAL E CG1 1 ATOM 5834 C CG2 . VAL E 2 143 ? 81.630 30.295 -7.002 1.00 28.45 ? 143 VAL E CG2 1 ATOM 5835 N N . SER E 2 144 ? 83.433 32.108 -2.989 1.00 23.35 ? 144 SER E N 1 ATOM 5836 C CA . SER E 2 144 ? 84.299 33.012 -2.247 1.00 27.09 ? 144 SER E CA 1 ATOM 5837 C C . SER E 2 144 ? 85.716 32.450 -2.121 1.00 29.24 ? 144 SER E C 1 ATOM 5838 O O . SER E 2 144 ? 85.941 31.260 -2.322 1.00 35.24 ? 144 SER E O 1 ATOM 5839 C CB . SER E 2 144 ? 83.708 33.244 -0.863 1.00 30.71 ? 144 SER E CB 1 ATOM 5840 O OG . SER E 2 144 ? 84.390 34.271 -0.175 1.00 39.20 ? 144 SER E OG 1 ATOM 5841 N N . THR E 2 145 ? 86.674 33.304 -1.784 1.00 29.26 ? 145 THR E N 1 ATOM 5842 C CA . THR E 2 145 ? 88.055 32.863 -1.644 1.00 28.63 ? 145 THR E CA 1 ATOM 5843 C C . THR E 2 145 ? 88.537 32.998 -0.216 1.00 29.79 ? 145 THR E C 1 ATOM 5844 O O . THR E 2 145 ? 89.663 32.627 0.092 1.00 34.34 ? 145 THR E O 1 ATOM 5845 C CB . THR E 2 145 ? 89.023 33.689 -2.519 1.00 25.73 ? 145 THR E CB 1 ATOM 5846 O OG1 . THR E 2 145 ? 89.119 35.017 -1.998 1.00 24.92 ? 145 THR E OG1 1 ATOM 5847 C CG2 . THR E 2 145 ? 88.532 33.761 -3.934 1.00 22.05 ? 145 THR E CG2 1 ATOM 5848 N N . GLY E 2 146 ? 87.701 33.545 0.653 1.00 28.85 ? 146 GLY E N 1 ATOM 5849 C CA . GLY E 2 146 ? 88.107 33.720 2.039 1.00 32.80 ? 146 GLY E CA 1 ATOM 5850 C C . GLY E 2 146 ? 89.235 34.722 2.255 1.00 31.83 ? 146 GLY E C 1 ATOM 5851 O O . GLY E 2 146 ? 89.898 35.127 1.301 1.00 30.86 ? 146 GLY E O 1 ATOM 5852 N N . LEU E 2 147 ? 89.453 35.121 3.510 1.00 32.35 ? 147 LEU E N 1 ATOM 5853 C CA . LEU E 2 147 ? 90.503 36.078 3.846 1.00 34.20 ? 147 LEU E CA 1 ATOM 5854 C C . LEU E 2 147 ? 91.839 35.545 3.360 1.00 37.72 ? 147 LEU E C 1 ATOM 5855 O O . LEU E 2 147 ? 92.195 34.402 3.641 1.00 39.71 ? 147 LEU E O 1 ATOM 5856 C CB . LEU E 2 147 ? 90.546 36.319 5.355 1.00 31.42 ? 147 LEU E CB 1 ATOM 5857 C CG . LEU E 2 147 ? 89.572 37.361 5.918 1.00 34.49 ? 147 LEU E CG 1 ATOM 5858 C CD1 . LEU E 2 147 ? 88.164 37.073 5.435 1.00 41.19 ? 147 LEU E CD1 1 ATOM 5859 C CD2 . LEU E 2 147 ? 89.607 37.350 7.443 1.00 33.97 ? 147 LEU E CD2 1 ATOM 5860 N N . ILE E 2 148 ? 92.574 36.390 2.639 1.00 39.47 ? 148 ILE E N 1 ATOM 5861 C CA . ILE E 2 148 ? 93.864 36.035 2.054 1.00 38.34 ? 148 ILE E CA 1 ATOM 5862 C C . ILE E 2 148 ? 95.004 36.921 2.530 1.00 40.45 ? 148 ILE E C 1 ATOM 5863 O O . ILE E 2 148 ? 95.339 37.902 1.869 1.00 39.15 ? 148 ILE E O 1 ATOM 5864 C CB . ILE E 2 148 ? 93.804 36.149 0.517 1.00 36.50 ? 148 ILE E CB 1 ATOM 5865 C CG1 . ILE E 2 148 ? 92.758 35.189 -0.036 1.00 35.13 ? 148 ILE E CG1 1 ATOM 5866 C CG2 . ILE E 2 148 ? 95.161 35.868 -0.090 1.00 36.03 ? 148 ILE E CG2 1 ATOM 5867 C CD1 . ILE E 2 148 ? 92.555 35.342 -1.520 1.00 38.32 ? 148 ILE E CD1 1 ATOM 5868 N N . GLN E 2 149 ? 95.611 36.565 3.656 1.00 44.39 ? 149 GLN E N 1 ATOM 5869 C CA . GLN E 2 149 ? 96.729 37.331 4.208 1.00 49.72 ? 149 GLN E CA 1 ATOM 5870 C C . GLN E 2 149 ? 97.765 37.658 3.124 1.00 50.35 ? 149 GLN E C 1 ATOM 5871 O O . GLN E 2 149 ? 98.284 36.758 2.465 1.00 52.30 ? 149 GLN E O 1 ATOM 5872 C CB . GLN E 2 149 ? 97.385 36.530 5.336 1.00 52.42 ? 149 GLN E CB 1 ATOM 5873 C CG . GLN E 2 149 ? 98.490 37.251 6.088 1.00 60.25 ? 149 GLN E CG 1 ATOM 5874 C CD . GLN E 2 149 ? 98.920 36.484 7.340 1.00 67.40 ? 149 GLN E CD 1 ATOM 5875 O OE1 . GLN E 2 149 ? 98.120 36.272 8.252 1.00 69.75 ? 149 GLN E OE1 1 ATOM 5876 N NE2 . GLN E 2 149 ? 100.182 36.064 7.387 1.00 68.44 ? 149 GLN E NE2 1 ATOM 5877 N N . ASN E 2 150 ? 98.047 38.945 2.930 1.00 50.52 ? 150 ASN E N 1 ATOM 5878 C CA . ASN E 2 150 ? 99.030 39.374 1.938 1.00 48.31 ? 150 ASN E CA 1 ATOM 5879 C C . ASN E 2 150 ? 100.404 39.395 2.586 1.00 48.77 ? 150 ASN E C 1 ATOM 5880 O O . ASN E 2 150 ? 101.411 39.568 1.904 1.00 46.87 ? 150 ASN E O 1 ATOM 5881 C CB . ASN E 2 150 ? 98.716 40.775 1.414 1.00 48.07 ? 150 ASN E CB 1 ATOM 5882 C CG . ASN E 2 150 ? 97.513 40.807 0.494 1.00 49.76 ? 150 ASN E CG 1 ATOM 5883 O OD1 . ASN E 2 150 ? 97.490 40.151 -0.552 1.00 51.68 ? 150 ASN E OD1 1 ATOM 5884 N ND2 . ASN E 2 150 ? 96.507 41.585 0.873 1.00 47.68 ? 150 ASN E ND2 1 ATOM 5885 N N . GLY E 2 151 ? 100.430 39.232 3.910 1.00 48.90 ? 151 GLY E N 1 ATOM 5886 C CA . GLY E 2 151 ? 101.687 39.226 4.640 1.00 49.38 ? 151 GLY E CA 1 ATOM 5887 C C . GLY E 2 151 ? 102.111 40.590 5.148 1.00 49.99 ? 151 GLY E C 1 ATOM 5888 O O . GLY E 2 151 ? 102.766 40.696 6.188 1.00 47.86 ? 151 GLY E O 1 ATOM 5889 N N . ASP E 2 152 ? 101.724 41.629 4.406 1.00 49.56 ? 152 ASP E N 1 ATOM 5890 C CA . ASP E 2 152 ? 102.041 43.020 4.737 1.00 47.30 ? 152 ASP E CA 1 ATOM 5891 C C . ASP E 2 152 ? 100.943 43.697 5.555 1.00 45.08 ? 152 ASP E C 1 ATOM 5892 O O . ASP E 2 152 ? 100.474 44.765 5.193 1.00 43.81 ? 152 ASP E O 1 ATOM 5893 C CB . ASP E 2 152 ? 102.245 43.832 3.457 1.00 46.77 ? 152 ASP E CB 1 ATOM 5894 C CG . ASP E 2 152 ? 100.965 43.974 2.649 1.00 48.18 ? 152 ASP E CG 1 ATOM 5895 O OD1 . ASP E 2 152 ? 99.879 43.730 3.218 1.00 45.40 ? 152 ASP E OD1 1 ATOM 5896 O OD2 . ASP E 2 152 ? 101.040 44.337 1.451 1.00 51.56 ? 152 ASP E OD2 1 ATOM 5897 N N . TRP E 2 153 ? 100.538 43.086 6.656 1.00 44.67 ? 153 TRP E N 1 ATOM 5898 C CA . TRP E 2 153 ? 99.479 43.648 7.487 1.00 44.51 ? 153 TRP E CA 1 ATOM 5899 C C . TRP E 2 153 ? 98.160 44.034 6.807 1.00 48.00 ? 153 TRP E C 1 ATOM 5900 O O . TRP E 2 153 ? 97.467 44.926 7.299 1.00 52.35 ? 153 TRP E O 1 ATOM 5901 C CB . TRP E 2 153 ? 99.988 44.850 8.270 1.00 34.79 ? 153 TRP E CB 1 ATOM 5902 C CG . TRP E 2 153 ? 100.736 44.459 9.469 1.00 29.67 ? 153 TRP E CG 1 ATOM 5903 C CD1 . TRP E 2 153 ? 102.053 44.131 9.533 1.00 28.37 ? 153 TRP E CD1 1 ATOM 5904 C CD2 . TRP E 2 153 ? 100.215 44.312 10.802 1.00 29.84 ? 153 TRP E CD2 1 ATOM 5905 N NE1 . TRP E 2 153 ? 102.396 43.786 10.827 1.00 28.08 ? 153 TRP E NE1 1 ATOM 5906 C CE2 . TRP E 2 153 ? 101.289 43.890 11.627 1.00 28.15 ? 153 TRP E CE2 1 ATOM 5907 C CE3 . TRP E 2 153 ? 98.948 44.494 11.381 1.00 29.47 ? 153 TRP E CE3 1 ATOM 5908 C CZ2 . TRP E 2 153 ? 101.139 43.649 13.006 1.00 28.30 ? 153 TRP E CZ2 1 ATOM 5909 C CZ3 . TRP E 2 153 ? 98.797 44.251 12.762 1.00 30.61 ? 153 TRP E CZ3 1 ATOM 5910 C CH2 . TRP E 2 153 ? 99.891 43.834 13.554 1.00 28.27 ? 153 TRP E CH2 1 ATOM 5911 N N . THR E 2 154 ? 97.820 43.396 5.681 1.00 47.66 ? 154 THR E N 1 ATOM 5912 C CA . THR E 2 154 ? 96.539 43.649 5.004 1.00 43.59 ? 154 THR E CA 1 ATOM 5913 C C . THR E 2 154 ? 96.095 42.411 4.239 1.00 45.05 ? 154 THR E C 1 ATOM 5914 O O . THR E 2 154 ? 96.907 41.758 3.578 1.00 44.32 ? 154 THR E O 1 ATOM 5915 C CB . THR E 2 154 ? 96.579 44.825 3.995 1.00 38.37 ? 154 THR E CB 1 ATOM 5916 O OG1 . THR E 2 154 ? 97.085 44.375 2.733 1.00 34.09 ? 154 THR E OG1 1 ATOM 5917 C CG2 . THR E 2 154 ? 97.438 45.937 4.518 1.00 40.38 ? 154 THR E CG2 1 ATOM 5918 N N . PHE E 2 155 ? 94.804 42.095 4.343 1.00 45.41 ? 155 PHE E N 1 ATOM 5919 C CA . PHE E 2 155 ? 94.210 40.943 3.663 1.00 44.18 ? 155 PHE E CA 1 ATOM 5920 C C . PHE E 2 155 ? 93.635 41.371 2.321 1.00 43.16 ? 155 PHE E C 1 ATOM 5921 O O . PHE E 2 155 ? 93.790 42.518 1.904 1.00 48.67 ? 155 PHE E O 1 ATOM 5922 C CB . PHE E 2 155 ? 93.073 40.342 4.499 1.00 42.84 ? 155 PHE E CB 1 ATOM 5923 C CG . PHE E 2 155 ? 93.469 39.974 5.891 1.00 45.40 ? 155 PHE E CG 1 ATOM 5924 C CD1 . PHE E 2 155 ? 93.654 40.951 6.855 1.00 44.99 ? 155 PHE E CD1 1 ATOM 5925 C CD2 . PHE E 2 155 ? 93.677 38.645 6.238 1.00 49.94 ? 155 PHE E CD2 1 ATOM 5926 C CE1 . PHE E 2 155 ? 94.042 40.615 8.151 1.00 50.97 ? 155 PHE E CE1 1 ATOM 5927 C CE2 . PHE E 2 155 ? 94.067 38.295 7.534 1.00 53.18 ? 155 PHE E CE2 1 ATOM 5928 C CZ . PHE E 2 155 ? 94.250 39.285 8.494 1.00 53.08 ? 155 PHE E CZ 1 ATOM 5929 N N . GLN E 2 156 ? 92.978 40.435 1.648 1.00 40.10 ? 156 GLN E N 1 ATOM 5930 C CA . GLN E 2 156 ? 92.324 40.695 0.371 1.00 36.92 ? 156 GLN E CA 1 ATOM 5931 C C . GLN E 2 156 ? 91.434 39.499 0.114 1.00 33.17 ? 156 GLN E C 1 ATOM 5932 O O . GLN E 2 156 ? 91.655 38.432 0.661 1.00 35.12 ? 156 GLN E O 1 ATOM 5933 C CB . GLN E 2 156 ? 93.328 40.842 -0.765 1.00 36.45 ? 156 GLN E CB 1 ATOM 5934 C CG . GLN E 2 156 ? 93.869 39.542 -1.282 1.00 40.23 ? 156 GLN E CG 1 ATOM 5935 C CD . GLN E 2 156 ? 94.405 39.684 -2.689 1.00 45.29 ? 156 GLN E CD 1 ATOM 5936 O OE1 . GLN E 2 156 ? 93.640 39.942 -3.631 1.00 40.26 ? 156 GLN E OE1 1 ATOM 5937 N NE2 . GLN E 2 156 ? 95.729 39.529 -2.846 1.00 44.99 ? 156 GLN E NE2 1 ATOM 5938 N N . THR E 2 157 ? 90.426 39.658 -0.714 1.00 27.64 ? 157 THR E N 1 ATOM 5939 C CA . THR E 2 157 ? 89.550 38.544 -0.946 1.00 27.69 ? 157 THR E CA 1 ATOM 5940 C C . THR E 2 157 ? 88.853 38.765 -2.249 1.00 29.17 ? 157 THR E C 1 ATOM 5941 O O . THR E 2 157 ? 88.897 39.855 -2.808 1.00 33.54 ? 157 THR E O 1 ATOM 5942 C CB . THR E 2 157 ? 88.482 38.432 0.168 1.00 29.64 ? 157 THR E CB 1 ATOM 5943 O OG1 . THR E 2 157 ? 87.787 37.185 0.047 1.00 31.84 ? 157 THR E OG1 1 ATOM 5944 C CG2 . THR E 2 157 ? 87.466 39.568 0.056 1.00 25.04 ? 157 THR E CG2 1 ATOM 5945 N N . LEU E 2 158 ? 88.217 37.717 -2.742 1.00 28.10 ? 158 LEU E N 1 ATOM 5946 C CA . LEU E 2 158 ? 87.480 37.803 -3.978 1.00 26.20 ? 158 LEU E CA 1 ATOM 5947 C C . LEU E 2 158 ? 86.209 37.014 -3.766 1.00 27.57 ? 158 LEU E C 1 ATOM 5948 O O . LEU E 2 158 ? 86.229 35.918 -3.220 1.00 31.28 ? 158 LEU E O 1 ATOM 5949 C CB . LEU E 2 158 ? 88.287 37.215 -5.133 1.00 23.23 ? 158 LEU E CB 1 ATOM 5950 C CG . LEU E 2 158 ? 89.558 37.976 -5.516 1.00 23.37 ? 158 LEU E CG 1 ATOM 5951 C CD1 . LEU E 2 158 ? 90.618 37.778 -4.458 1.00 30.67 ? 158 LEU E CD1 1 ATOM 5952 C CD2 . LEU E 2 158 ? 90.081 37.475 -6.836 1.00 23.75 ? 158 LEU E CD2 1 ATOM 5953 N N . VAL E 2 159 ? 85.093 37.594 -4.164 1.00 26.31 ? 159 VAL E N 1 ATOM 5954 C CA . VAL E 2 159 ? 83.825 36.928 -4.026 1.00 23.84 ? 159 VAL E CA 1 ATOM 5955 C C . VAL E 2 159 ? 83.224 36.973 -5.411 1.00 26.06 ? 159 VAL E C 1 ATOM 5956 O O . VAL E 2 159 ? 82.887 38.043 -5.921 1.00 25.86 ? 159 VAL E O 1 ATOM 5957 C CB . VAL E 2 159 ? 82.958 37.653 -3.016 1.00 22.89 ? 159 VAL E CB 1 ATOM 5958 C CG1 . VAL E 2 159 ? 81.566 37.064 -3.006 1.00 25.65 ? 159 VAL E CG1 1 ATOM 5959 C CG2 . VAL E 2 159 ? 83.600 37.541 -1.640 1.00 19.01 ? 159 VAL E CG2 1 ATOM 5960 N N . MET E 2 160 ? 83.125 35.799 -6.024 1.00 26.47 ? 160 MET E N 1 ATOM 5961 C CA . MET E 2 160 ? 82.614 35.669 -7.378 1.00 26.81 ? 160 MET E CA 1 ATOM 5962 C C . MET E 2 160 ? 81.184 35.186 -7.409 1.00 24.71 ? 160 MET E C 1 ATOM 5963 O O . MET E 2 160 ? 80.842 34.181 -6.812 1.00 26.57 ? 160 MET E O 1 ATOM 5964 C CB . MET E 2 160 ? 83.510 34.719 -8.153 1.00 29.34 ? 160 MET E CB 1 ATOM 5965 C CG . MET E 2 160 ? 84.979 34.939 -7.837 1.00 34.23 ? 160 MET E CG 1 ATOM 5966 S SD . MET E 2 160 ? 86.050 33.872 -8.777 1.00 42.27 ? 160 MET E SD 1 ATOM 5967 C CE . MET E 2 160 ? 84.966 32.434 -9.005 1.00 41.57 ? 160 MET E CE 1 ATOM 5968 N N . LEU E 2 161 ? 80.357 35.919 -8.132 1.00 25.93 ? 161 LEU E N 1 ATOM 5969 C CA . LEU E 2 161 ? 78.941 35.630 -8.252 1.00 27.36 ? 161 LEU E CA 1 ATOM 5970 C C . LEU E 2 161 ? 78.650 35.075 -9.641 1.00 27.29 ? 161 LEU E C 1 ATOM 5971 O O . LEU E 2 161 ? 78.631 35.811 -10.618 1.00 29.89 ? 161 LEU E O 1 ATOM 5972 C CB . LEU E 2 161 ? 78.165 36.931 -8.037 1.00 26.93 ? 161 LEU E CB 1 ATOM 5973 C CG . LEU E 2 161 ? 76.677 36.926 -7.714 1.00 28.15 ? 161 LEU E CG 1 ATOM 5974 C CD1 . LEU E 2 161 ? 76.066 38.136 -8.372 1.00 30.31 ? 161 LEU E CD1 1 ATOM 5975 C CD2 . LEU E 2 161 ? 76.005 35.678 -8.228 1.00 31.22 ? 161 LEU E CD2 1 ATOM 5976 N N . GLU E 2 162 ? 78.414 33.781 -9.745 1.00 29.46 ? 162 GLU E N 1 ATOM 5977 C CA . GLU E 2 162 ? 78.141 33.225 -11.054 1.00 35.56 ? 162 GLU E CA 1 ATOM 5978 C C . GLU E 2 162 ? 76.712 33.516 -11.458 1.00 38.38 ? 162 GLU E C 1 ATOM 5979 O O . GLU E 2 162 ? 75.781 33.155 -10.752 1.00 40.69 ? 162 GLU E O 1 ATOM 5980 C CB . GLU E 2 162 ? 78.413 31.717 -11.069 1.00 35.18 ? 162 GLU E CB 1 ATOM 5981 C CG . GLU E 2 162 ? 77.751 30.936 -9.952 1.00 36.78 ? 162 GLU E CG 1 ATOM 5982 C CD . GLU E 2 162 ? 78.241 29.495 -9.880 1.00 37.96 ? 162 GLU E CD 1 ATOM 5983 O OE1 . GLU E 2 162 ? 79.463 29.289 -9.668 1.00 28.51 ? 162 GLU E OE1 1 ATOM 5984 O OE2 . GLU E 2 162 ? 77.398 28.575 -10.034 1.00 39.97 ? 162 GLU E OE2 1 ATOM 5985 N N . THR E 2 163 ? 76.547 34.199 -12.587 1.00 44.08 ? 163 THR E N 1 ATOM 5986 C CA . THR E 2 163 ? 75.219 34.532 -13.103 1.00 49.68 ? 163 THR E CA 1 ATOM 5987 C C . THR E 2 163 ? 75.246 34.619 -14.605 1.00 49.68 ? 163 THR E C 1 ATOM 5988 O O . THR E 2 163 ? 76.298 34.544 -15.228 1.00 50.59 ? 163 THR E O 1 ATOM 5989 C CB . THR E 2 163 ? 74.723 35.908 -12.664 1.00 53.94 ? 163 THR E CB 1 ATOM 5990 O OG1 . THR E 2 163 ? 75.472 36.913 -13.365 1.00 54.08 ? 163 THR E OG1 1 ATOM 5991 C CG2 . THR E 2 163 ? 74.860 36.086 -11.159 1.00 57.46 ? 163 THR E CG2 1 ATOM 5992 N N . VAL E 2 164 ? 74.067 34.819 -15.172 1.00 52.22 ? 164 VAL E N 1 ATOM 5993 C CA . VAL E 2 164 ? 73.928 34.953 -16.606 1.00 56.58 ? 164 VAL E CA 1 ATOM 5994 C C . VAL E 2 164 ? 73.442 36.365 -16.943 1.00 59.53 ? 164 VAL E C 1 ATOM 5995 O O . VAL E 2 164 ? 72.247 36.592 -17.135 1.00 58.90 ? 164 VAL E O 1 ATOM 5996 C CB . VAL E 2 164 ? 72.947 33.903 -17.167 1.00 54.12 ? 164 VAL E CB 1 ATOM 5997 C CG1 . VAL E 2 164 ? 73.582 32.532 -17.102 1.00 51.61 ? 164 VAL E CG1 1 ATOM 5998 C CG2 . VAL E 2 164 ? 71.656 33.910 -16.368 1.00 56.16 ? 164 VAL E CG2 1 ATOM 5999 N N . PRO E 2 165 ? 74.374 37.338 -16.998 1.00 61.93 ? 165 PRO E N 1 ATOM 6000 C CA . PRO E 2 165 ? 74.041 38.726 -17.311 1.00 63.56 ? 165 PRO E CA 1 ATOM 6001 C C . PRO E 2 165 ? 72.992 38.808 -18.402 1.00 67.06 ? 165 PRO E C 1 ATOM 6002 O O . PRO E 2 165 ? 73.106 38.167 -19.450 1.00 66.41 ? 165 PRO E O 1 ATOM 6003 C CB . PRO E 2 165 ? 75.380 39.300 -17.739 1.00 61.78 ? 165 PRO E CB 1 ATOM 6004 C CG . PRO E 2 165 ? 76.298 38.650 -16.780 1.00 61.99 ? 165 PRO E CG 1 ATOM 6005 C CD . PRO E 2 165 ? 75.825 37.202 -16.774 1.00 61.94 ? 165 PRO E CD 1 ATOM 6006 N N . ARG E 2 166 ? 71.963 39.601 -18.139 1.00 70.66 ? 166 ARG E N 1 ATOM 6007 C CA . ARG E 2 166 ? 70.870 39.774 -19.077 1.00 73.79 ? 166 ARG E CA 1 ATOM 6008 C C . ARG E 2 166 ? 70.573 41.262 -19.238 1.00 76.29 ? 166 ARG E C 1 ATOM 6009 O O . ARG E 2 166 ? 69.658 41.802 -18.608 1.00 78.98 ? 166 ARG E O 1 ATOM 6010 C CB . ARG E 2 166 ? 69.658 39.026 -18.545 1.00 74.24 ? 166 ARG E CB 1 ATOM 6011 C CG . ARG E 2 166 ? 68.398 39.133 -19.356 1.00 78.79 ? 166 ARG E CG 1 ATOM 6012 C CD . ARG E 2 166 ? 67.352 38.298 -18.658 1.00 83.69 ? 166 ARG E CD 1 ATOM 6013 N NE . ARG E 2 166 ? 67.588 38.330 -17.217 1.00 88.28 ? 166 ARG E NE 1 ATOM 6014 C CZ . ARG E 2 166 ? 66.894 37.641 -16.320 1.00 92.54 ? 166 ARG E CZ 1 ATOM 6015 N NH1 . ARG E 2 166 ? 65.899 36.852 -16.706 1.00 94.61 ? 166 ARG E NH1 1 ATOM 6016 N NH2 . ARG E 2 166 ? 67.204 37.738 -15.032 1.00 94.97 ? 166 ARG E NH2 1 ATOM 6017 N N . SER E 2 167 ? 71.378 41.906 -20.084 1.00 77.08 ? 167 SER E N 1 ATOM 6018 C CA . SER E 2 167 ? 71.290 43.333 -20.393 1.00 75.05 ? 167 SER E CA 1 ATOM 6019 C C . SER E 2 167 ? 70.128 44.071 -19.739 1.00 73.47 ? 167 SER E C 1 ATOM 6020 O O . SER E 2 167 ? 68.958 43.732 -19.923 1.00 71.89 ? 167 SER E O 1 ATOM 6021 C CB . SER E 2 167 ? 71.251 43.525 -21.911 1.00 75.36 ? 167 SER E CB 1 ATOM 6022 O OG . SER E 2 167 ? 72.409 42.963 -22.517 1.00 78.22 ? 167 SER E OG 1 ATOM 6023 N N . GLY E 2 168 ? 70.466 45.090 -18.965 1.00 71.41 ? 168 GLY E N 1 ATOM 6024 C CA . GLY E 2 168 ? 69.438 45.854 -18.298 1.00 71.66 ? 168 GLY E CA 1 ATOM 6025 C C . GLY E 2 168 ? 69.576 45.698 -16.806 1.00 71.67 ? 168 GLY E C 1 ATOM 6026 O O . GLY E 2 168 ? 69.071 46.517 -16.034 1.00 73.14 ? 168 GLY E O 1 ATOM 6027 N N . GLU E 2 169 ? 70.270 44.639 -16.400 1.00 70.22 ? 169 GLU E N 1 ATOM 6028 C CA . GLU E 2 169 ? 70.484 44.367 -14.984 1.00 66.42 ? 169 GLU E CA 1 ATOM 6029 C C . GLU E 2 169 ? 71.706 45.118 -14.488 1.00 63.41 ? 169 GLU E C 1 ATOM 6030 O O . GLU E 2 169 ? 72.629 45.402 -15.259 1.00 62.19 ? 169 GLU E O 1 ATOM 6031 C CB . GLU E 2 169 ? 70.729 42.879 -14.746 1.00 65.71 ? 169 GLU E CB 1 ATOM 6032 C CG . GLU E 2 169 ? 69.691 41.946 -15.302 1.00 66.39 ? 169 GLU E CG 1 ATOM 6033 C CD . GLU E 2 169 ? 70.108 40.501 -15.132 1.00 69.38 ? 169 GLU E CD 1 ATOM 6034 O OE1 . GLU E 2 169 ? 71.260 40.177 -15.510 1.00 68.15 ? 169 GLU E OE1 1 ATOM 6035 O OE2 . GLU E 2 169 ? 69.291 39.697 -14.624 1.00 69.41 ? 169 GLU E OE2 1 ATOM 6036 N N . VAL E 2 170 ? 71.701 45.444 -13.200 1.00 58.80 ? 170 VAL E N 1 ATOM 6037 C CA . VAL E 2 170 ? 72.838 46.107 -12.588 1.00 56.33 ? 170 VAL E CA 1 ATOM 6038 C C . VAL E 2 170 ? 73.228 45.291 -11.366 1.00 54.07 ? 170 VAL E C 1 ATOM 6039 O O . VAL E 2 170 ? 72.487 45.214 -10.379 1.00 52.97 ? 170 VAL E O 1 ATOM 6040 C CB . VAL E 2 170 ? 72.532 47.567 -12.172 1.00 54.87 ? 170 VAL E CB 1 ATOM 6041 C CG1 . VAL E 2 170 ? 72.022 48.328 -13.363 1.00 57.00 ? 170 VAL E CG1 1 ATOM 6042 C CG2 . VAL E 2 170 ? 71.530 47.612 -11.037 1.00 57.08 ? 170 VAL E CG2 1 ATOM 6043 N N . TYR E 2 171 ? 74.379 44.638 -11.459 1.00 49.99 ? 171 TYR E N 1 ATOM 6044 C CA . TYR E 2 171 ? 74.861 43.843 -10.351 1.00 46.78 ? 171 TYR E CA 1 ATOM 6045 C C . TYR E 2 171 ? 75.559 44.801 -9.408 1.00 46.00 ? 171 TYR E C 1 ATOM 6046 O O . TYR E 2 171 ? 76.028 45.866 -9.831 1.00 44.36 ? 171 TYR E O 1 ATOM 6047 C CB . TYR E 2 171 ? 75.794 42.742 -10.849 1.00 42.01 ? 171 TYR E CB 1 ATOM 6048 C CG . TYR E 2 171 ? 75.035 41.665 -11.567 1.00 37.79 ? 171 TYR E CG 1 ATOM 6049 C CD1 . TYR E 2 171 ? 74.562 41.864 -12.865 1.00 37.03 ? 171 TYR E CD1 1 ATOM 6050 C CD2 . TYR E 2 171 ? 74.711 40.479 -10.922 1.00 35.36 ? 171 TYR E CD2 1 ATOM 6051 C CE1 . TYR E 2 171 ? 73.778 40.907 -13.499 1.00 37.42 ? 171 TYR E CE1 1 ATOM 6052 C CE2 . TYR E 2 171 ? 73.931 39.516 -11.540 1.00 35.76 ? 171 TYR E CE2 1 ATOM 6053 C CZ . TYR E 2 171 ? 73.466 39.734 -12.827 1.00 37.87 ? 171 TYR E CZ 1 ATOM 6054 O OH . TYR E 2 171 ? 72.685 38.774 -13.429 1.00 39.43 ? 171 TYR E OH 1 ATOM 6055 N N . THR E 2 172 ? 75.616 44.439 -8.131 1.00 42.48 ? 172 THR E N 1 ATOM 6056 C CA . THR E 2 172 ? 76.221 45.326 -7.167 1.00 39.05 ? 172 THR E CA 1 ATOM 6057 C C . THR E 2 172 ? 76.809 44.603 -6.002 1.00 33.93 ? 172 THR E C 1 ATOM 6058 O O . THR E 2 172 ? 76.117 43.861 -5.322 1.00 30.98 ? 172 THR E O 1 ATOM 6059 C CB . THR E 2 172 ? 75.194 46.299 -6.604 1.00 44.83 ? 172 THR E CB 1 ATOM 6060 O OG1 . THR E 2 172 ? 74.418 46.850 -7.675 1.00 52.46 ? 172 THR E OG1 1 ATOM 6061 C CG2 . THR E 2 172 ? 75.891 47.422 -5.863 1.00 47.84 ? 172 THR E CG2 1 ATOM 6062 N N . CYS E 2 173 ? 78.087 44.860 -5.762 1.00 31.96 ? 173 CYS E N 1 ATOM 6063 C CA . CYS E 2 173 ? 78.803 44.258 -4.655 1.00 33.98 ? 173 CYS E CA 1 ATOM 6064 C C . CYS E 2 173 ? 78.726 45.233 -3.489 1.00 33.18 ? 173 CYS E C 1 ATOM 6065 O O . CYS E 2 173 ? 78.778 46.434 -3.696 1.00 33.06 ? 173 CYS E O 1 ATOM 6066 C CB . CYS E 2 173 ? 80.258 44.024 -5.055 1.00 36.81 ? 173 CYS E CB 1 ATOM 6067 S SG . CYS E 2 173 ? 81.264 43.177 -3.797 1.00 40.91 ? 173 CYS E SG 1 ATOM 6068 N N . GLN E 2 174 ? 78.598 44.720 -2.270 1.00 34.80 ? 174 GLN E N 1 ATOM 6069 C CA . GLN E 2 174 ? 78.511 45.569 -1.080 1.00 36.09 ? 174 GLN E CA 1 ATOM 6070 C C . GLN E 2 174 ? 79.513 45.083 -0.028 1.00 39.81 ? 174 GLN E C 1 ATOM 6071 O O . GLN E 2 174 ? 79.566 43.887 0.266 1.00 43.17 ? 174 GLN E O 1 ATOM 6072 C CB . GLN E 2 174 ? 77.104 45.496 -0.500 1.00 32.40 ? 174 GLN E CB 1 ATOM 6073 C CG . GLN E 2 174 ? 76.846 46.512 0.565 1.00 32.64 ? 174 GLN E CG 1 ATOM 6074 C CD . GLN E 2 174 ? 75.741 46.095 1.500 1.00 34.82 ? 174 GLN E CD 1 ATOM 6075 O OE1 . GLN E 2 174 ? 75.946 45.261 2.382 1.00 35.48 ? 174 GLN E OE1 1 ATOM 6076 N NE2 . GLN E 2 174 ? 74.557 46.671 1.315 1.00 33.14 ? 174 GLN E NE2 1 ATOM 6077 N N . VAL E 2 175 ? 80.288 45.996 0.554 1.00 39.13 ? 175 VAL E N 1 ATOM 6078 C CA . VAL E 2 175 ? 81.297 45.607 1.543 1.00 39.67 ? 175 VAL E CA 1 ATOM 6079 C C . VAL E 2 175 ? 81.191 46.332 2.873 1.00 42.04 ? 175 VAL E C 1 ATOM 6080 O O . VAL E 2 175 ? 81.241 47.552 2.916 1.00 44.71 ? 175 VAL E O 1 ATOM 6081 C CB . VAL E 2 175 ? 82.717 45.860 1.006 1.00 38.32 ? 175 VAL E CB 1 ATOM 6082 C CG1 . VAL E 2 175 ? 83.749 45.442 2.035 1.00 38.79 ? 175 VAL E CG1 1 ATOM 6083 C CG2 . VAL E 2 175 ? 82.919 45.109 -0.293 1.00 41.67 ? 175 VAL E CG2 1 ATOM 6084 N N . GLU E 2 176 ? 81.061 45.579 3.959 1.00 44.78 ? 176 GLU E N 1 ATOM 6085 C CA . GLU E 2 176 ? 80.970 46.171 5.290 1.00 48.66 ? 176 GLU E CA 1 ATOM 6086 C C . GLU E 2 176 ? 82.226 45.814 6.033 1.00 50.61 ? 176 GLU E C 1 ATOM 6087 O O . GLU E 2 176 ? 82.441 44.657 6.366 1.00 52.13 ? 176 GLU E O 1 ATOM 6088 C CB . GLU E 2 176 ? 79.798 45.604 6.088 1.00 51.97 ? 176 GLU E CB 1 ATOM 6089 C CG . GLU E 2 176 ? 78.416 46.048 5.669 1.00 54.23 ? 176 GLU E CG 1 ATOM 6090 C CD . GLU E 2 176 ? 77.347 45.103 6.197 1.00 57.46 ? 176 GLU E CD 1 ATOM 6091 O OE1 . GLU E 2 176 ? 77.183 45.000 7.438 1.00 53.62 ? 176 GLU E OE1 1 ATOM 6092 O OE2 . GLU E 2 176 ? 76.680 44.450 5.359 1.00 59.53 ? 176 GLU E OE2 1 ATOM 6093 N N . HIS E 2 177 ? 83.053 46.807 6.300 1.00 54.89 ? 177 HIS E N 1 ATOM 6094 C CA . HIS E 2 177 ? 84.287 46.580 7.026 1.00 59.89 ? 177 HIS E CA 1 ATOM 6095 C C . HIS E 2 177 ? 84.249 47.538 8.212 1.00 62.23 ? 177 HIS E C 1 ATOM 6096 O O . HIS E 2 177 ? 83.621 48.592 8.132 1.00 64.72 ? 177 HIS E O 1 ATOM 6097 C CB . HIS E 2 177 ? 85.474 46.879 6.110 1.00 61.07 ? 177 HIS E CB 1 ATOM 6098 C CG . HIS E 2 177 ? 86.800 46.546 6.711 1.00 64.35 ? 177 HIS E CG 1 ATOM 6099 N ND1 . HIS E 2 177 ? 87.360 47.281 7.731 1.00 66.52 ? 177 HIS E ND1 1 ATOM 6100 C CD2 . HIS E 2 177 ? 87.678 45.551 6.440 1.00 68.15 ? 177 HIS E CD2 1 ATOM 6101 C CE1 . HIS E 2 177 ? 88.527 46.757 8.061 1.00 69.25 ? 177 HIS E CE1 1 ATOM 6102 N NE2 . HIS E 2 177 ? 88.744 45.705 7.293 1.00 69.10 ? 177 HIS E NE2 1 ATOM 6103 N N . PRO E 2 178 ? 84.887 47.179 9.340 1.00 63.18 ? 178 PRO E N 1 ATOM 6104 C CA . PRO E 2 178 ? 84.858 48.099 10.482 1.00 63.78 ? 178 PRO E CA 1 ATOM 6105 C C . PRO E 2 178 ? 85.644 49.356 10.143 1.00 64.99 ? 178 PRO E C 1 ATOM 6106 O O . PRO E 2 178 ? 85.796 50.255 10.963 1.00 66.74 ? 178 PRO E O 1 ATOM 6107 C CB . PRO E 2 178 ? 85.500 47.283 11.598 1.00 61.99 ? 178 PRO E CB 1 ATOM 6108 C CG . PRO E 2 178 ? 86.464 46.432 10.858 1.00 62.73 ? 178 PRO E CG 1 ATOM 6109 C CD . PRO E 2 178 ? 85.650 45.966 9.672 1.00 62.75 ? 178 PRO E CD 1 ATOM 6110 N N . SER E 2 179 ? 86.139 49.397 8.913 1.00 66.70 ? 179 SER E N 1 ATOM 6111 C CA . SER E 2 179 ? 86.901 50.527 8.406 1.00 68.12 ? 179 SER E CA 1 ATOM 6112 C C . SER E 2 179 ? 85.956 51.681 8.068 1.00 67.87 ? 179 SER E C 1 ATOM 6113 O O . SER E 2 179 ? 86.319 52.847 8.170 1.00 69.28 ? 179 SER E O 1 ATOM 6114 C CB . SER E 2 179 ? 87.671 50.100 7.150 1.00 70.50 ? 179 SER E CB 1 ATOM 6115 O OG . SER E 2 179 ? 88.353 51.186 6.552 1.00 72.78 ? 179 SER E OG 1 ATOM 6116 N N . VAL E 2 180 ? 84.733 51.357 7.674 1.00 67.94 ? 180 VAL E N 1 ATOM 6117 C CA . VAL E 2 180 ? 83.777 52.391 7.321 1.00 66.35 ? 180 VAL E CA 1 ATOM 6118 C C . VAL E 2 180 ? 82.476 52.313 8.114 1.00 68.61 ? 180 VAL E C 1 ATOM 6119 O O . VAL E 2 180 ? 82.292 51.461 8.987 1.00 67.66 ? 180 VAL E O 1 ATOM 6120 C CB . VAL E 2 180 ? 83.434 52.313 5.831 1.00 63.87 ? 180 VAL E CB 1 ATOM 6121 C CG1 . VAL E 2 180 ? 84.700 52.430 5.002 1.00 60.40 ? 180 VAL E CG1 1 ATOM 6122 C CG2 . VAL E 2 180 ? 82.722 51.001 5.539 1.00 60.74 ? 180 VAL E CG2 1 ATOM 6123 N N . THR E 2 181 ? 81.575 53.229 7.790 1.00 70.07 ? 181 THR E N 1 ATOM 6124 C CA . THR E 2 181 ? 80.266 53.308 8.421 1.00 71.50 ? 181 THR E CA 1 ATOM 6125 C C . THR E 2 181 ? 79.284 53.274 7.267 1.00 71.82 ? 181 THR E C 1 ATOM 6126 O O . THR E 2 181 ? 78.116 52.909 7.407 1.00 72.11 ? 181 THR E O 1 ATOM 6127 C CB . THR E 2 181 ? 80.107 54.631 9.144 1.00 71.11 ? 181 THR E CB 1 ATOM 6128 O OG1 . THR E 2 181 ? 80.596 55.675 8.293 1.00 68.46 ? 181 THR E OG1 1 ATOM 6129 C CG2 . THR E 2 181 ? 80.873 54.621 10.462 1.00 70.57 ? 181 THR E CG2 1 ATOM 6130 N N . SER E 2 182 ? 79.794 53.677 6.116 1.00 70.55 ? 182 SER E N 1 ATOM 6131 C CA . SER E 2 182 ? 79.025 53.705 4.897 1.00 70.54 ? 182 SER E CA 1 ATOM 6132 C C . SER E 2 182 ? 79.443 52.473 4.130 1.00 68.52 ? 182 SER E C 1 ATOM 6133 O O . SER E 2 182 ? 80.430 52.498 3.404 1.00 69.79 ? 182 SER E O 1 ATOM 6134 C CB . SER E 2 182 ? 79.386 54.952 4.105 1.00 75.96 ? 182 SER E CB 1 ATOM 6135 O OG . SER E 2 182 ? 80.797 55.058 3.981 1.00 80.23 ? 182 SER E OG 1 ATOM 6136 N N . PRO E 2 183 ? 78.702 51.373 4.284 1.00 66.96 ? 183 PRO E N 1 ATOM 6137 C CA . PRO E 2 183 ? 79.049 50.140 3.573 1.00 64.64 ? 183 PRO E CA 1 ATOM 6138 C C . PRO E 2 183 ? 79.296 50.398 2.088 1.00 61.11 ? 183 PRO E C 1 ATOM 6139 O O . PRO E 2 183 ? 78.393 50.819 1.363 1.00 60.69 ? 183 PRO E O 1 ATOM 6140 C CB . PRO E 2 183 ? 77.840 49.245 3.827 1.00 64.49 ? 183 PRO E CB 1 ATOM 6141 C CG . PRO E 2 183 ? 76.731 50.228 3.937 1.00 66.62 ? 183 PRO E CG 1 ATOM 6142 C CD . PRO E 2 183 ? 77.336 51.293 4.819 1.00 66.62 ? 183 PRO E CD 1 ATOM 6143 N N . LEU E 2 184 ? 80.530 50.147 1.656 1.00 56.34 ? 184 LEU E N 1 ATOM 6144 C CA . LEU E 2 184 ? 80.944 50.355 0.273 1.00 51.69 ? 184 LEU E CA 1 ATOM 6145 C C . LEU E 2 184 ? 80.116 49.587 -0.748 1.00 50.20 ? 184 LEU E C 1 ATOM 6146 O O . LEU E 2 184 ? 79.694 48.453 -0.502 1.00 50.44 ? 184 LEU E O 1 ATOM 6147 C CB . LEU E 2 184 ? 82.412 49.962 0.091 1.00 47.69 ? 184 LEU E CB 1 ATOM 6148 C CG . LEU E 2 184 ? 83.514 50.786 0.755 1.00 46.70 ? 184 LEU E CG 1 ATOM 6149 C CD1 . LEU E 2 184 ? 83.601 50.479 2.241 1.00 46.88 ? 184 LEU E CD1 1 ATOM 6150 C CD2 . LEU E 2 184 ? 84.826 50.464 0.082 1.00 45.42 ? 184 LEU E CD2 1 ATOM 6151 N N . THR E 2 185 ? 79.893 50.213 -1.899 1.00 46.79 ? 185 THR E N 1 ATOM 6152 C CA . THR E 2 185 ? 79.148 49.575 -2.973 1.00 47.19 ? 185 THR E CA 1 ATOM 6153 C C . THR E 2 185 ? 79.820 49.856 -4.324 1.00 47.48 ? 185 THR E C 1 ATOM 6154 O O . THR E 2 185 ? 80.482 50.880 -4.503 1.00 47.01 ? 185 THR E O 1 ATOM 6155 C CB . THR E 2 185 ? 77.655 50.043 -3.018 1.00 45.14 ? 185 THR E CB 1 ATOM 6156 O OG1 . THR E 2 185 ? 77.594 51.461 -3.181 1.00 49.88 ? 185 THR E OG1 1 ATOM 6157 C CG2 . THR E 2 185 ? 76.925 49.663 -1.741 1.00 41.89 ? 185 THR E CG2 1 ATOM 6158 N N . VAL E 2 186 ? 79.672 48.912 -5.252 1.00 47.29 ? 186 VAL E N 1 ATOM 6159 C CA . VAL E 2 186 ? 80.224 49.017 -6.601 1.00 44.81 ? 186 VAL E CA 1 ATOM 6160 C C . VAL E 2 186 ? 79.251 48.327 -7.528 1.00 46.98 ? 186 VAL E C 1 ATOM 6161 O O . VAL E 2 186 ? 78.714 47.272 -7.202 1.00 48.03 ? 186 VAL E O 1 ATOM 6162 C CB . VAL E 2 186 ? 81.569 48.309 -6.743 1.00 40.53 ? 186 VAL E CB 1 ATOM 6163 C CG1 . VAL E 2 186 ? 81.984 48.299 -8.208 1.00 34.27 ? 186 VAL E CG1 1 ATOM 6164 C CG2 . VAL E 2 186 ? 82.612 48.998 -5.882 1.00 39.46 ? 186 VAL E CG2 1 ATOM 6165 N N . GLU E 2 187 ? 79.024 48.918 -8.687 1.00 49.14 ? 187 GLU E N 1 ATOM 6166 C CA . GLU E 2 187 ? 78.091 48.334 -9.619 1.00 52.53 ? 187 GLU E CA 1 ATOM 6167 C C . GLU E 2 187 ? 78.776 47.932 -10.898 1.00 52.92 ? 187 GLU E C 1 ATOM 6168 O O . GLU E 2 187 ? 79.883 48.368 -11.215 1.00 52.87 ? 187 GLU E O 1 ATOM 6169 C CB . GLU E 2 187 ? 76.960 49.317 -9.942 1.00 59.26 ? 187 GLU E CB 1 ATOM 6170 C CG . GLU E 2 187 ? 76.251 49.896 -8.719 1.00 68.57 ? 187 GLU E CG 1 ATOM 6171 C CD . GLU E 2 187 ? 75.127 50.870 -9.075 1.00 73.85 ? 187 GLU E CD 1 ATOM 6172 O OE1 . GLU E 2 187 ? 75.360 51.777 -9.911 1.00 75.54 ? 187 GLU E OE1 1 ATOM 6173 O OE2 . GLU E 2 187 ? 74.016 50.731 -8.506 1.00 76.08 ? 187 GLU E OE2 1 ATOM 6174 N N . TRP E 2 188 ? 78.080 47.082 -11.627 1.00 54.27 ? 188 TRP E N 1 ATOM 6175 C CA . TRP E 2 188 ? 78.531 46.580 -12.901 1.00 57.91 ? 188 TRP E CA 1 ATOM 6176 C C . TRP E 2 188 ? 77.208 46.224 -13.543 1.00 61.89 ? 188 TRP E C 1 ATOM 6177 O O . TRP E 2 188 ? 76.478 45.388 -13.012 1.00 62.65 ? 188 TRP E O 1 ATOM 6178 C CB . TRP E 2 188 ? 79.369 45.318 -12.718 1.00 55.03 ? 188 TRP E CB 1 ATOM 6179 C CG . TRP E 2 188 ? 79.875 44.796 -14.008 1.00 53.90 ? 188 TRP E CG 1 ATOM 6180 C CD1 . TRP E 2 188 ? 81.032 45.146 -14.629 1.00 55.36 ? 188 TRP E CD1 1 ATOM 6181 C CD2 . TRP E 2 188 ? 79.196 43.902 -14.896 1.00 52.61 ? 188 TRP E CD2 1 ATOM 6182 N NE1 . TRP E 2 188 ? 81.116 44.532 -15.855 1.00 54.26 ? 188 TRP E NE1 1 ATOM 6183 C CE2 . TRP E 2 188 ? 80.000 43.761 -16.042 1.00 52.44 ? 188 TRP E CE2 1 ATOM 6184 C CE3 . TRP E 2 188 ? 77.983 43.206 -14.834 1.00 55.11 ? 188 TRP E CE3 1 ATOM 6185 C CZ2 . TRP E 2 188 ? 79.632 42.951 -17.121 1.00 55.15 ? 188 TRP E CZ2 1 ATOM 6186 C CZ3 . TRP E 2 188 ? 77.617 42.397 -15.910 1.00 55.17 ? 188 TRP E CZ3 1 ATOM 6187 C CH2 . TRP E 2 188 ? 78.439 42.278 -17.036 1.00 53.41 ? 188 TRP E CH2 1 ATOM 6188 N N . ARG E 2 189 ? 76.873 46.870 -14.655 1.00 65.46 ? 189 ARG E N 1 ATOM 6189 C CA . ARG E 2 189 ? 75.607 46.575 -15.300 1.00 70.17 ? 189 ARG E CA 1 ATOM 6190 C C . ARG E 2 189 ? 75.781 45.906 -16.638 1.00 71.75 ? 189 ARG E C 1 ATOM 6191 O O . ARG E 2 189 ? 76.721 46.196 -17.375 1.00 70.45 ? 189 ARG E O 1 ATOM 6192 C CB . ARG E 2 189 ? 74.750 47.843 -15.442 1.00 74.51 ? 189 ARG E CB 1 ATOM 6193 C CG . ARG E 2 189 ? 75.444 49.057 -16.045 1.00 81.30 ? 189 ARG E CG 1 ATOM 6194 C CD . ARG E 2 189 ? 75.367 50.270 -15.098 1.00 88.13 ? 189 ARG E CD 1 ATOM 6195 N NE . ARG E 2 189 ? 73.997 50.618 -14.709 1.00 92.52 ? 189 ARG E NE 1 ATOM 6196 C CZ . ARG E 2 189 ? 73.129 51.273 -15.479 1.00 94.27 ? 189 ARG E CZ 1 ATOM 6197 N NH1 . ARG E 2 189 ? 73.485 51.667 -16.697 1.00 95.52 ? 189 ARG E NH1 1 ATOM 6198 N NH2 . ARG E 2 189 ? 71.900 51.528 -15.033 1.00 92.83 ? 189 ARG E NH2 1 ATOM 6199 N N . ALA E 2 190 ? 74.859 44.993 -16.928 1.00 75.85 ? 190 ALA E N 1 ATOM 6200 C CA . ALA E 2 190 ? 74.855 44.233 -18.168 1.00 81.11 ? 190 ALA E CA 1 ATOM 6201 C C . ALA E 2 190 ? 74.877 45.146 -19.396 1.00 85.28 ? 190 ALA E C 1 ATOM 6202 O O . ALA E 2 190 ? 73.795 45.357 -19.993 1.00 89.24 ? 190 ALA E O 1 ATOM 6203 C CB . ALA E 2 190 ? 73.634 43.323 -18.204 1.00 78.07 ? 190 ALA E CB 1 ATOM 6204 O OXT . ALA E 2 190 ? 75.973 45.651 -19.739 1.00 87.06 ? 190 ALA E OXT 1 ATOM 6205 N N . GLY F 3 1 ? 101.917 53.520 22.751 1.00 107.15 ? 628 GLY F N 1 ATOM 6206 C CA . GLY F 3 1 ? 103.333 53.117 22.490 1.00 106.60 ? 628 GLY F CA 1 ATOM 6207 C C . GLY F 3 1 ? 104.087 52.731 23.752 1.00 106.68 ? 628 GLY F C 1 ATOM 6208 O O . GLY F 3 1 ? 103.471 52.476 24.789 1.00 107.30 ? 628 GLY F O 1 ATOM 6209 N N . GLY F 3 2 ? 105.417 52.686 23.668 1.00 105.88 ? 629 GLY F N 1 ATOM 6210 C CA . GLY F 3 2 ? 106.229 52.330 24.825 1.00 103.43 ? 629 GLY F CA 1 ATOM 6211 C C . GLY F 3 2 ? 107.344 51.339 24.526 1.00 101.83 ? 629 GLY F C 1 ATOM 6212 O O . GLY F 3 2 ? 108.104 51.507 23.568 1.00 101.39 ? 629 GLY F O 1 ATOM 6213 N N . VAL F 3 3 ? 107.453 50.302 25.353 1.00 99.82 ? 630 VAL F N 1 ATOM 6214 C CA . VAL F 3 3 ? 108.482 49.293 25.151 1.00 96.46 ? 630 VAL F CA 1 ATOM 6215 C C . VAL F 3 3 ? 107.985 47.874 25.399 1.00 95.00 ? 630 VAL F C 1 ATOM 6216 O O . VAL F 3 3 ? 107.257 47.592 26.359 1.00 91.24 ? 630 VAL F O 1 ATOM 6217 C CB . VAL F 3 3 ? 109.721 49.570 26.031 1.00 96.05 ? 630 VAL F CB 1 ATOM 6218 C CG1 . VAL F 3 3 ? 110.692 48.402 25.954 1.00 95.24 ? 630 VAL F CG1 1 ATOM 6219 C CG2 . VAL F 3 3 ? 110.412 50.840 25.553 1.00 95.00 ? 630 VAL F CG2 1 ATOM 6220 N N . TYR F 3 4 ? 108.403 46.988 24.503 1.00 94.51 ? 631 TYR F N 1 ATOM 6221 C CA . TYR F 3 4 ? 108.032 45.586 24.545 1.00 94.30 ? 631 TYR F CA 1 ATOM 6222 C C . TYR F 3 4 ? 108.825 44.736 25.519 1.00 94.69 ? 631 TYR F C 1 ATOM 6223 O O . TYR F 3 4 ? 110.031 44.910 25.686 1.00 95.76 ? 631 TYR F O 1 ATOM 6224 C CB . TYR F 3 4 ? 108.160 44.984 23.147 1.00 93.12 ? 631 TYR F CB 1 ATOM 6225 C CG . TYR F 3 4 ? 106.991 45.302 22.254 1.00 93.71 ? 631 TYR F CG 1 ATOM 6226 C CD1 . TYR F 3 4 ? 105.700 44.917 22.616 1.00 93.90 ? 631 TYR F CD1 1 ATOM 6227 C CD2 . TYR F 3 4 ? 107.167 45.984 21.048 1.00 93.17 ? 631 TYR F CD2 1 ATOM 6228 C CE1 . TYR F 3 4 ? 104.612 45.201 21.805 1.00 95.20 ? 631 TYR F CE1 1 ATOM 6229 C CE2 . TYR F 3 4 ? 106.083 46.275 20.225 1.00 94.16 ? 631 TYR F CE2 1 ATOM 6230 C CZ . TYR F 3 4 ? 104.808 45.880 20.611 1.00 96.27 ? 631 TYR F CZ 1 ATOM 6231 O OH . TYR F 3 4 ? 103.727 46.158 19.810 1.00 98.24 ? 631 TYR F OH 1 ATOM 6232 N N . HIS F 3 5 ? 108.128 43.805 26.156 1.00 95.20 ? 632 HIS F N 1 ATOM 6233 C CA . HIS F 3 5 ? 108.752 42.888 27.095 1.00 97.26 ? 632 HIS F CA 1 ATOM 6234 C C . HIS F 3 5 ? 108.820 41.517 26.445 1.00 97.19 ? 632 HIS F C 1 ATOM 6235 O O . HIS F 3 5 ? 107.873 41.094 25.777 1.00 97.58 ? 632 HIS F O 1 ATOM 6236 C CB . HIS F 3 5 ? 107.927 42.763 28.374 1.00 99.71 ? 632 HIS F CB 1 ATOM 6237 C CG . HIS F 3 5 ? 107.879 44.009 29.194 1.00 102.65 ? 632 HIS F CG 1 ATOM 6238 N ND1 . HIS F 3 5 ? 107.272 44.056 30.431 1.00 104.38 ? 632 HIS F ND1 1 ATOM 6239 C CD2 . HIS F 3 5 ? 108.347 45.256 28.954 1.00 104.47 ? 632 HIS F CD2 1 ATOM 6240 C CE1 . HIS F 3 5 ? 107.367 45.281 30.918 1.00 106.16 ? 632 HIS F CE1 1 ATOM 6241 N NE2 . HIS F 3 5 ? 108.014 46.028 30.041 1.00 108.29 ? 632 HIS F NE2 1 ATOM 6242 N N . PHE F 3 6 ? 109.935 40.824 26.637 1.00 95.91 ? 633 PHE F N 1 ATOM 6243 C CA . PHE F 3 6 ? 110.079 39.487 26.089 1.00 95.37 ? 633 PHE F CA 1 ATOM 6244 C C . PHE F 3 6 ? 110.430 38.551 27.235 1.00 93.79 ? 633 PHE F C 1 ATOM 6245 O O . PHE F 3 6 ? 111.255 38.889 28.081 1.00 93.63 ? 633 PHE F O 1 ATOM 6246 C CB . PHE F 3 6 ? 111.179 39.441 25.020 1.00 97.15 ? 633 PHE F CB 1 ATOM 6247 C CG . PHE F 3 6 ? 112.573 39.590 25.566 1.00 99.72 ? 633 PHE F CG 1 ATOM 6248 C CD1 . PHE F 3 6 ? 113.066 40.840 25.929 1.00 99.57 ? 633 PHE F CD1 1 ATOM 6249 C CD2 . PHE F 3 6 ? 113.397 38.473 25.710 1.00 100.79 ? 633 PHE F CD2 1 ATOM 6250 C CE1 . PHE F 3 6 ? 114.363 40.977 26.427 1.00 101.99 ? 633 PHE F CE1 1 ATOM 6251 C CE2 . PHE F 3 6 ? 114.696 38.598 26.209 1.00 101.38 ? 633 PHE F CE2 1 ATOM 6252 C CZ . PHE F 3 6 ? 115.181 39.852 26.567 1.00 102.08 ? 633 PHE F CZ 1 ATOM 6253 N N . VAL F 3 7 ? 109.791 37.388 27.281 1.00 92.87 ? 634 VAL F N 1 ATOM 6254 C CA . VAL F 3 7 ? 110.081 36.429 28.334 1.00 90.71 ? 634 VAL F CA 1 ATOM 6255 C C . VAL F 3 7 ? 111.461 35.856 28.025 1.00 91.82 ? 634 VAL F C 1 ATOM 6256 O O . VAL F 3 7 ? 111.838 35.722 26.857 1.00 89.71 ? 634 VAL F O 1 ATOM 6257 C CB . VAL F 3 7 ? 109.053 35.283 28.364 1.00 89.22 ? 634 VAL F CB 1 ATOM 6258 C CG1 . VAL F 3 7 ? 109.073 34.626 29.730 1.00 88.44 ? 634 VAL F CG1 1 ATOM 6259 C CG2 . VAL F 3 7 ? 107.665 35.801 28.035 1.00 86.77 ? 634 VAL F CG2 1 ATOM 6260 N N . LYS F 3 8 ? 112.216 35.519 29.064 1.00 93.96 ? 635 LYS F N 1 ATOM 6261 C CA . LYS F 3 8 ? 113.554 34.987 28.863 1.00 97.64 ? 635 LYS F CA 1 ATOM 6262 C C . LYS F 3 8 ? 113.630 33.472 28.899 1.00 99.53 ? 635 LYS F C 1 ATOM 6263 O O . LYS F 3 8 ? 112.928 32.815 29.671 1.00 96.52 ? 635 LYS F O 1 ATOM 6264 C CB . LYS F 3 8 ? 114.506 35.583 29.895 1.00 100.33 ? 635 LYS F CB 1 ATOM 6265 C CG . LYS F 3 8 ? 114.642 37.087 29.759 1.00 106.03 ? 635 LYS F CG 1 ATOM 6266 C CD . LYS F 3 8 ? 115.605 37.668 30.779 1.00 111.94 ? 635 LYS F CD 1 ATOM 6267 C CE . LYS F 3 8 ? 115.710 39.184 30.629 1.00 114.49 ? 635 LYS F CE 1 ATOM 6268 N NZ . LYS F 3 8 ? 116.605 39.790 31.656 1.00 116.13 ? 635 LYS F NZ 1 ATOM 6269 N N . LYS F 3 9 ? 114.496 32.932 28.047 1.00 104.02 ? 636 LYS F N 1 ATOM 6270 C CA . LYS F 3 9 ? 114.702 31.492 27.934 1.00 109.25 ? 636 LYS F CA 1 ATOM 6271 C C . LYS F 3 9 ? 115.700 30.997 28.978 1.00 112.44 ? 636 LYS F C 1 ATOM 6272 O O . LYS F 3 9 ? 116.822 31.499 29.064 1.00 114.18 ? 636 LYS F O 1 ATOM 6273 C CB . LYS F 3 9 ? 115.210 31.142 26.523 1.00 108.03 ? 636 LYS F CB 1 ATOM 6274 C CG . LYS F 3 9 ? 115.449 29.647 26.270 1.00 107.88 ? 636 LYS F CG 1 ATOM 6275 C CD . LYS F 3 9 ? 114.169 28.831 26.464 1.00 107.39 ? 636 LYS F CD 1 ATOM 6276 C CE . LYS F 3 9 ? 114.391 27.341 26.237 1.00 104.37 ? 636 LYS F CE 1 ATOM 6277 N NZ . LYS F 3 9 ? 113.152 26.565 26.537 1.00 101.30 ? 636 LYS F NZ 1 ATOM 6278 N N . HIS F 3 10 ? 115.282 30.016 29.772 1.00 116.03 ? 637 HIS F N 1 ATOM 6279 C CA . HIS F 3 10 ? 116.135 29.432 30.805 1.00 119.40 ? 637 HIS F CA 1 ATOM 6280 C C . HIS F 3 10 ? 116.294 27.943 30.502 1.00 120.58 ? 637 HIS F C 1 ATOM 6281 O O . HIS F 3 10 ? 115.311 27.248 30.249 1.00 122.47 ? 637 HIS F O 1 ATOM 6282 C CB . HIS F 3 10 ? 115.504 29.640 32.186 1.00 119.58 ? 637 HIS F CB 1 ATOM 6283 C CG . HIS F 3 10 ? 115.348 31.082 32.564 1.00 121.09 ? 637 HIS F CG 1 ATOM 6284 N ND1 . HIS F 3 10 ? 116.422 31.898 32.845 1.00 122.40 ? 637 HIS F ND1 1 ATOM 6285 C CD2 . HIS F 3 10 ? 114.246 31.863 32.673 1.00 121.51 ? 637 HIS F CD2 1 ATOM 6286 C CE1 . HIS F 3 10 ? 115.991 33.119 33.111 1.00 122.51 ? 637 HIS F CE1 1 ATOM 6287 N NE2 . HIS F 3 10 ? 114.674 33.125 33.013 1.00 122.10 ? 637 HIS F NE2 1 ATOM 6288 N N . VAL F 3 11 ? 117.527 27.452 30.521 1.00 121.45 ? 638 VAL F N 1 ATOM 6289 C CA . VAL F 3 11 ? 117.763 26.049 30.209 1.00 123.14 ? 638 VAL F CA 1 ATOM 6290 C C . VAL F 3 11 ? 118.180 25.222 31.424 1.00 125.64 ? 638 VAL F C 1 ATOM 6291 O O . VAL F 3 11 ? 118.792 25.744 32.360 1.00 126.85 ? 638 VAL F O 1 ATOM 6292 C CB . VAL F 3 11 ? 118.839 25.919 29.110 1.00 121.85 ? 638 VAL F CB 1 ATOM 6293 C CG1 . VAL F 3 11 ? 120.204 26.295 29.671 1.00 120.19 ? 638 VAL F CG1 1 ATOM 6294 C CG2 . VAL F 3 11 ? 118.839 24.510 28.545 1.00 121.13 ? 638 VAL F CG2 1 ATOM 6295 N N . HIS F 3 12 ? 117.842 23.932 31.400 1.00 127.54 ? 639 HIS F N 1 ATOM 6296 C CA . HIS F 3 12 ? 118.178 23.019 32.492 1.00 129.07 ? 639 HIS F CA 1 ATOM 6297 C C . HIS F 3 12 ? 118.688 21.667 32.008 1.00 130.27 ? 639 HIS F C 1 ATOM 6298 O O . HIS F 3 12 ? 117.906 20.817 31.576 1.00 128.29 ? 639 HIS F O 1 ATOM 6299 C CB . HIS F 3 12 ? 116.964 22.784 33.393 1.00 128.63 ? 639 HIS F CB 1 ATOM 6300 C CG . HIS F 3 12 ? 117.201 21.764 34.465 1.00 129.15 ? 639 HIS F CG 1 ATOM 6301 N ND1 . HIS F 3 12 ? 118.180 21.909 35.425 1.00 130.32 ? 639 HIS F ND1 1 ATOM 6302 C CD2 . HIS F 3 12 ? 116.589 20.585 34.726 1.00 128.84 ? 639 HIS F CD2 1 ATOM 6303 C CE1 . HIS F 3 12 ? 118.159 20.862 36.232 1.00 130.64 ? 639 HIS F CE1 1 ATOM 6304 N NE2 . HIS F 3 12 ? 117.203 20.044 35.830 1.00 129.59 ? 639 HIS F NE2 1 ATOM 6305 N N . GLU F 3 13 ? 120.001 21.471 32.091 1.00 132.97 ? 640 GLU F N 1 ATOM 6306 C CA . GLU F 3 13 ? 120.601 20.209 31.682 1.00 136.27 ? 640 GLU F CA 1 ATOM 6307 C C . GLU F 3 13 ? 120.513 19.215 32.832 1.00 138.24 ? 640 GLU F C 1 ATOM 6308 O O . GLU F 3 13 ? 120.867 19.532 33.971 1.00 139.21 ? 640 GLU F O 1 ATOM 6309 C CB . GLU F 3 13 ? 122.069 20.404 31.284 1.00 136.59 ? 640 GLU F CB 1 ATOM 6310 C CG . GLU F 3 13 ? 122.817 19.090 31.052 1.00 137.62 ? 640 GLU F CG 1 ATOM 6311 C CD . GLU F 3 13 ? 124.256 19.293 30.611 1.00 138.96 ? 640 GLU F CD 1 ATOM 6312 O OE1 . GLU F 3 13 ? 124.960 20.121 31.232 1.00 139.68 ? 640 GLU F OE1 1 ATOM 6313 O OE2 . GLU F 3 13 ? 124.685 18.616 29.650 1.00 139.12 ? 640 GLU F OE2 1 ATOM 6314 N N . SER F 3 14 ? 120.035 18.013 32.527 1.00 139.94 ? 641 SER F N 1 ATOM 6315 C CA . SER F 3 14 ? 119.899 16.961 33.528 1.00 141.72 ? 641 SER F CA 1 ATOM 6316 C C . SER F 3 14 ? 120.658 15.698 33.111 1.00 142.54 ? 641 SER F C 1 ATOM 6317 O O . SER F 3 14 ? 121.249 15.707 32.007 1.00 143.66 ? 641 SER F O 1 ATOM 6318 C CB . SER F 3 14 ? 118.413 16.644 33.757 1.00 141.25 ? 641 SER F CB 1 ATOM 6319 O OG . SER F 3 14 ? 117.718 16.468 32.532 1.00 140.41 ? 641 SER F OG 1 ATOM 6320 O OXT . SER F 3 14 ? 120.661 14.720 33.893 1.00 142.68 ? 641 SER F OXT 1 HETATM 6321 C C1 . NAG G 4 . ? 76.671 17.586 7.579 1.00 73.10 ? 1183 NAG A C1 1 HETATM 6322 C C2 . NAG G 4 . ? 76.803 18.751 8.547 1.00 76.59 ? 1183 NAG A C2 1 HETATM 6323 C C3 . NAG G 4 . ? 75.820 18.577 9.692 1.00 85.64 ? 1183 NAG A C3 1 HETATM 6324 C C4 . NAG G 4 . ? 74.407 18.722 9.135 1.00 90.92 ? 1183 NAG A C4 1 HETATM 6325 C C5 . NAG G 4 . ? 74.258 17.971 7.802 1.00 87.66 ? 1183 NAG A C5 1 HETATM 6326 C C6 . NAG G 4 . ? 74.227 18.890 6.595 1.00 90.42 ? 1183 NAG A C6 1 HETATM 6327 C C7 . NAG G 4 . ? 78.776 20.018 8.996 1.00 69.45 ? 1183 NAG A C7 1 HETATM 6328 C C8 . NAG G 4 . ? 78.249 21.140 9.879 1.00 70.04 ? 1183 NAG A C8 1 HETATM 6329 N N2 . NAG G 4 . ? 78.152 18.850 9.052 1.00 70.64 ? 1183 NAG A N2 1 HETATM 6330 O O3 . NAG G 4 . ? 76.061 19.561 10.687 1.00 89.22 ? 1183 NAG A O3 1 HETATM 6331 O O4 . NAG G 4 . ? 73.449 18.223 10.087 1.00 104.34 ? 1183 NAG A O4 1 HETATM 6332 O O5 . NAG G 4 . ? 75.338 17.012 7.612 1.00 80.97 ? 1183 NAG A O5 1 HETATM 6333 O O6 . NAG G 4 . ? 75.047 20.032 6.804 1.00 94.42 ? 1183 NAG A O6 1 HETATM 6334 O O7 . NAG G 4 . ? 79.739 20.217 8.268 1.00 69.08 ? 1183 NAG A O7 1 HETATM 6335 C C1 . NAG H 4 . ? 72.354 19.046 10.329 1.00 118.79 ? 1184 NAG A C1 1 HETATM 6336 C C2 . NAG H 4 . ? 72.696 20.147 11.366 1.00 124.56 ? 1184 NAG A C2 1 HETATM 6337 C C3 . NAG H 4 . ? 72.987 19.557 12.755 1.00 125.07 ? 1184 NAG A C3 1 HETATM 6338 C C4 . NAG H 4 . ? 72.260 18.220 12.969 1.00 125.39 ? 1184 NAG A C4 1 HETATM 6339 C C5 . NAG H 4 . ? 70.961 18.152 12.153 1.00 124.25 ? 1184 NAG A C5 1 HETATM 6340 C C6 . NAG H 4 . ? 69.953 19.240 12.490 1.00 124.60 ? 1184 NAG A C6 1 HETATM 6341 C C7 . NAG H 4 . ? 74.312 21.932 11.648 1.00 133.00 ? 1184 NAG A C7 1 HETATM 6342 C C8 . NAG H 4 . ? 75.538 21.656 12.509 1.00 132.91 ? 1184 NAG A C8 1 HETATM 6343 N N2 . NAG H 4 . ? 73.839 20.926 10.913 1.00 130.09 ? 1184 NAG A N2 1 HETATM 6344 O O3 . NAG H 4 . ? 72.578 20.483 13.754 1.00 122.35 ? 1184 NAG A O3 1 HETATM 6345 O O4 . NAG H 4 . ? 73.111 17.141 12.603 1.00 125.60 ? 1184 NAG A O4 1 HETATM 6346 O O5 . NAG H 4 . ? 71.223 18.223 10.721 1.00 122.24 ? 1184 NAG A O5 1 HETATM 6347 O O6 . NAG H 4 . ? 68.632 18.836 12.161 1.00 125.53 ? 1184 NAG A O6 1 HETATM 6348 O O7 . NAG H 4 . ? 73.803 23.055 11.651 1.00 135.13 ? 1184 NAG A O7 1 HETATM 6349 C C1 . NAG I 4 . ? 90.063 19.579 33.109 1.00 106.49 ? 1185 NAG A C1 1 HETATM 6350 C C2 . NAG I 4 . ? 90.632 19.873 34.510 1.00 111.79 ? 1185 NAG A C2 1 HETATM 6351 C C3 . NAG I 4 . ? 89.734 20.914 35.187 1.00 113.76 ? 1185 NAG A C3 1 HETATM 6352 C C4 . NAG I 4 . ? 89.799 22.192 34.353 1.00 113.46 ? 1185 NAG A C4 1 HETATM 6353 C C5 . NAG I 4 . ? 89.309 21.903 32.916 1.00 111.29 ? 1185 NAG A C5 1 HETATM 6354 C C6 . NAG I 4 . ? 89.517 23.109 32.004 1.00 108.36 ? 1185 NAG A C6 1 HETATM 6355 C C7 . NAG I 4 . ? 91.832 18.479 36.068 1.00 114.75 ? 1185 NAG A C7 1 HETATM 6356 C C8 . NAG I 4 . ? 91.674 18.702 37.565 1.00 115.77 ? 1185 NAG A C8 1 HETATM 6357 N N2 . NAG I 4 . ? 90.751 18.667 35.310 1.00 114.14 ? 1185 NAG A N2 1 HETATM 6358 O O3 . NAG I 4 . ? 90.175 21.170 36.515 1.00 116.26 ? 1185 NAG A O3 1 HETATM 6359 O O4 . NAG I 4 . ? 89.013 23.213 34.959 1.00 113.15 ? 1185 NAG A O4 1 HETATM 6360 O O5 . NAG I 4 . ? 90.057 20.797 32.321 1.00 110.72 ? 1185 NAG A O5 1 HETATM 6361 O O6 . NAG I 4 . ? 88.284 23.698 31.618 1.00 102.48 ? 1185 NAG A O6 1 HETATM 6362 O O7 . NAG I 4 . ? 92.931 18.148 35.609 1.00 112.68 ? 1185 NAG A O7 1 HETATM 6363 C C1 . NAG J 4 . ? 119.088 26.817 -0.942 1.00 122.04 ? 1183 NAG D C1 1 HETATM 6364 C C2 . NAG J 4 . ? 119.931 26.790 0.341 1.00 128.18 ? 1183 NAG D C2 1 HETATM 6365 C C3 . NAG J 4 . ? 121.318 26.193 0.037 1.00 130.81 ? 1183 NAG D C3 1 HETATM 6366 C C4 . NAG J 4 . ? 121.210 24.864 -0.728 1.00 130.98 ? 1183 NAG D C4 1 HETATM 6367 C C5 . NAG J 4 . ? 120.270 25.006 -1.932 1.00 127.06 ? 1183 NAG D C5 1 HETATM 6368 C C6 . NAG J 4 . ? 120.019 23.693 -2.642 1.00 125.20 ? 1183 NAG D C6 1 HETATM 6369 C C7 . NAG J 4 . ? 119.564 28.491 2.030 1.00 136.16 ? 1183 NAG D C7 1 HETATM 6370 C C8 . NAG J 4 . ? 118.239 29.240 2.020 1.00 136.09 ? 1183 NAG D C8 1 HETATM 6371 N N2 . NAG J 4 . ? 120.084 28.142 0.854 1.00 133.07 ? 1183 NAG D N2 1 HETATM 6372 O O3 . NAG J 4 . ? 122.026 25.980 1.251 1.00 133.12 ? 1183 NAG D O3 1 HETATM 6373 O O4 . NAG J 4 . ? 122.502 24.465 -1.174 1.00 133.47 ? 1183 NAG D O4 1 HETATM 6374 O O5 . NAG J 4 . ? 118.989 25.502 -1.498 1.00 123.78 ? 1183 NAG D O5 1 HETATM 6375 O O6 . NAG J 4 . ? 118.693 23.627 -3.142 1.00 122.00 ? 1183 NAG D O6 1 HETATM 6376 O O7 . NAG J 4 . ? 120.115 28.244 3.105 1.00 138.82 ? 1183 NAG D O7 1 HETATM 6377 C C1 . NAG K 4 . ? 117.670 5.208 21.790 1.00 151.46 ? 1184 NAG D C1 1 HETATM 6378 C C2 . NAG K 4 . ? 118.310 4.233 22.813 1.00 156.17 ? 1184 NAG D C2 1 HETATM 6379 C C3 . NAG K 4 . ? 119.518 3.495 22.207 1.00 158.46 ? 1184 NAG D C3 1 HETATM 6380 C C4 . NAG K 4 . ? 119.142 2.869 20.860 1.00 158.53 ? 1184 NAG D C4 1 HETATM 6381 C C5 . NAG K 4 . ? 118.598 3.961 19.938 1.00 157.60 ? 1184 NAG D C5 1 HETATM 6382 C C6 . NAG K 4 . ? 118.208 3.433 18.565 1.00 157.19 ? 1184 NAG D C6 1 HETATM 6383 C C7 . NAG K 4 . ? 118.799 4.314 25.185 1.00 160.46 ? 1184 NAG D C7 1 HETATM 6384 C C8 . NAG K 4 . ? 120.186 3.906 25.663 1.00 159.81 ? 1184 NAG D C8 1 HETATM 6385 N N2 . NAG K 4 . ? 118.713 4.947 24.014 1.00 159.05 ? 1184 NAG D N2 1 HETATM 6386 O O3 . NAG K 4 . ? 119.954 2.476 23.097 1.00 160.69 ? 1184 NAG D O3 1 HETATM 6387 O O4 . NAG K 4 . ? 120.279 2.249 20.270 1.00 158.66 ? 1184 NAG D O4 1 HETATM 6388 O O5 . NAG K 4 . ? 117.414 4.555 20.528 1.00 155.35 ? 1184 NAG D O5 1 HETATM 6389 O O6 . NAG K 4 . ? 119.353 3.198 17.754 1.00 155.35 ? 1184 NAG D O6 1 HETATM 6390 O O7 . NAG K 4 . ? 117.814 4.057 25.881 1.00 161.58 ? 1184 NAG D O7 1 HETATM 6391 O O . HOH L 5 . ? 85.467 0.706 -1.746 1.00 23.87 ? 2001 HOH A O 1 HETATM 6392 O O . HOH L 5 . ? 92.449 4.564 -3.412 1.00 38.67 ? 2002 HOH A O 1 HETATM 6393 O O . HOH L 5 . ? 83.536 -4.788 -3.200 1.00 35.66 ? 2003 HOH A O 1 HETATM 6394 O O . HOH L 5 . ? 87.234 -5.923 -13.083 1.00 44.65 ? 2004 HOH A O 1 HETATM 6395 O O . HOH L 5 . ? 99.992 6.732 4.813 1.00 32.75 ? 2005 HOH A O 1 HETATM 6396 O O . HOH L 5 . ? 93.731 18.350 17.332 1.00 17.99 ? 2006 HOH A O 1 HETATM 6397 O O . HOH L 5 . ? 90.873 25.042 -0.189 1.00 25.08 ? 2007 HOH A O 1 HETATM 6398 O O . HOH L 5 . ? 93.729 19.771 -2.251 1.00 17.94 ? 2008 HOH A O 1 HETATM 6399 O O . HOH L 5 . ? 87.018 15.080 -21.755 1.00 23.67 ? 2009 HOH A O 1 HETATM 6400 O O . HOH L 5 . ? 103.092 5.462 4.834 1.00 34.41 ? 2010 HOH A O 1 HETATM 6401 O O . HOH L 5 . ? 108.206 10.306 5.724 1.00 27.44 ? 2011 HOH A O 1 HETATM 6402 O O . HOH L 5 . ? 103.316 11.163 12.456 1.00 16.92 ? 2012 HOH A O 1 HETATM 6403 O O . HOH M 5 . ? 119.660 -6.687 -2.416 1.00 32.76 ? 2001 HOH B O 1 HETATM 6404 O O . HOH M 5 . ? 102.911 9.955 15.212 1.00 11.11 ? 2002 HOH B O 1 HETATM 6405 O O . HOH M 5 . ? 108.280 1.265 19.901 1.00 29.05 ? 2003 HOH B O 1 HETATM 6406 O O . HOH M 5 . ? 107.311 -15.368 7.473 1.00 29.87 ? 2004 HOH B O 1 HETATM 6407 O O . HOH M 5 . ? 98.329 -6.750 0.639 1.00 12.85 ? 2005 HOH B O 1 HETATM 6408 O O . HOH M 5 . ? 101.044 -13.461 -6.298 1.00 29.42 ? 2006 HOH B O 1 HETATM 6409 O O . HOH M 5 . ? 115.317 12.794 -28.792 1.00 27.97 ? 2007 HOH B O 1 HETATM 6410 O O . HOH M 5 . ? 101.589 16.574 -5.530 1.00 43.77 ? 2008 HOH B O 1 HETATM 6411 O O . HOH N 5 . ? 101.951 29.968 16.734 1.00 17.80 ? 2001 HOH D O 1 HETATM 6412 O O . HOH N 5 . ? 98.672 30.455 16.843 1.00 20.16 ? 2002 HOH D O 1 HETATM 6413 O O . HOH O 5 . ? 125.450 12.971 5.075 1.00 38.84 ? 2001 HOH E O 1 HETATM 6414 O O . HOH O 5 . ? 114.629 18.084 35.630 1.00 43.64 ? 2002 HOH E O 1 HETATM 6415 O O . HOH O 5 . ? 113.065 24.863 29.180 1.00 39.33 ? 2003 HOH E O 1 HETATM 6416 O O . HOH O 5 . ? 102.253 47.645 32.423 1.00 38.15 ? 2004 HOH E O 1 HETATM 6417 O O . HOH O 5 . ? 89.835 36.587 -17.558 1.00 46.97 ? 2005 HOH E O 1 HETATM 6418 O O . HOH O 5 . ? 93.961 42.388 14.405 1.00 34.15 ? 2006 HOH E O 1 HETATM 6419 O O . HOH O 5 . ? 65.250 36.604 -9.443 1.00 22.26 ? 2007 HOH E O 1 HETATM 6420 O O . HOH O 5 . ? 93.135 40.149 -6.228 1.00 28.33 ? 2008 HOH E O 1 # _database_PDB_caveat.id 1 _database_PDB_caveat.text 'NAG A 1184 HAS WRONG CHIRALITY AT ATOM C1 NAG D 1184 HAS WRONG CHIRALITY AT ATOM C1' # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ILE 1 1 ? ? ? A . n A 1 2 LYS 2 2 ? ? ? A . n A 1 3 GLU 3 3 3 GLU GLU A . n A 1 4 GLU 4 4 4 GLU GLU A . n A 1 5 HIS 5 5 5 HIS HIS A . n A 1 6 VAL 6 6 6 VAL VAL A . n A 1 7 ILE 7 7 7 ILE ILE A . n A 1 8 ILE 8 8 8 ILE ILE A . n A 1 9 GLN 9 9 9 GLN GLN A . n A 1 10 ALA 10 10 10 ALA ALA A . n A 1 11 GLU 11 11 11 GLU GLU A . n A 1 12 PHE 12 12 12 PHE PHE A . n A 1 13 TYR 13 13 13 TYR TYR A . n A 1 14 LEU 14 14 14 LEU LEU A . n A 1 15 ASN 15 15 15 ASN ASN A . n A 1 16 PRO 16 16 16 PRO PRO A . n A 1 17 ASP 17 17 17 ASP ASP A . n A 1 18 GLN 18 18 18 GLN GLN A . n A 1 19 SER 19 19 19 SER SER A . n A 1 20 GLY 20 20 20 GLY GLY A . n A 1 21 GLU 21 21 21 GLU GLU A . n A 1 22 PHE 22 22 22 PHE PHE A . n A 1 23 MET 23 23 23 MET MET A . n A 1 24 PHE 24 24 24 PHE PHE A . n A 1 25 ASP 25 25 25 ASP ASP A . n A 1 26 PHE 26 26 26 PHE PHE A . n A 1 27 ASP 27 27 27 ASP ASP A . n A 1 28 GLY 28 28 28 GLY GLY A . n A 1 29 ASP 29 29 29 ASP ASP A . n A 1 30 GLU 30 30 30 GLU GLU A . n A 1 31 ILE 31 31 31 ILE ILE A . n A 1 32 PHE 32 32 32 PHE PHE A . n A 1 33 HIS 33 33 33 HIS HIS A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 ASP 35 35 35 ASP ASP A . n A 1 36 MET 36 36 36 MET MET A . n A 1 37 ALA 37 37 37 ALA ALA A . n A 1 38 LYS 38 38 38 LYS LYS A . n A 1 39 LYS 39 39 39 LYS LYS A . n A 1 40 GLU 40 40 40 GLU GLU A . n A 1 41 THR 41 41 41 THR THR A . n A 1 42 VAL 42 42 42 VAL VAL A . n A 1 43 TRP 43 43 43 TRP TRP A . n A 1 44 ARG 44 44 44 ARG ARG A . n A 1 45 LEU 45 45 45 LEU LEU A . n A 1 46 GLU 46 46 46 GLU GLU A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 PHE 48 48 48 PHE PHE A . n A 1 49 GLY 49 49 49 GLY GLY A . n A 1 50 ARG 50 50 50 ARG ARG A . n A 1 51 PHE 51 51 51 PHE PHE A . n A 1 52 ALA 52 52 52 ALA ALA A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 GLU 55 55 55 GLU GLU A . n A 1 56 ALA 56 56 56 ALA ALA A . n A 1 57 GLN 57 57 57 GLN GLN A . n A 1 58 GLY 58 58 58 GLY GLY A . n A 1 59 ALA 59 59 59 ALA ALA A . n A 1 60 LEU 60 60 60 LEU LEU A . n A 1 61 ALA 61 61 61 ALA ALA A . n A 1 62 ASN 62 62 62 ASN ASN A . n A 1 63 ILE 63 63 63 ILE ILE A . n A 1 64 ALA 64 64 64 ALA ALA A . n A 1 65 VAL 65 65 65 VAL VAL A . n A 1 66 ASP 66 66 66 ASP ASP A . n A 1 67 LYS 67 67 67 LYS LYS A . n A 1 68 ALA 68 68 68 ALA ALA A . n A 1 69 ASN 69 69 69 ASN ASN A . n A 1 70 LEU 70 70 70 LEU LEU A . n A 1 71 GLU 71 71 71 GLU GLU A . n A 1 72 ILE 72 72 72 ILE ILE A . n A 1 73 MET 73 73 73 MET MET A . n A 1 74 THR 74 74 74 THR THR A . n A 1 75 LYS 75 75 75 LYS LYS A . n A 1 76 ARG 76 76 76 ARG ARG A . n A 1 77 SER 77 77 77 SER SER A . n A 1 78 ASN 78 78 78 ASN ASN A . n A 1 79 TYR 79 79 79 TYR TYR A . n A 1 80 THR 80 80 80 THR THR A . n A 1 81 PRO 81 81 81 PRO PRO A . n A 1 82 ILE 82 82 82 ILE ILE A . n A 1 83 THR 83 83 83 THR THR A . n A 1 84 ASN 84 84 84 ASN ASN A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 PRO 86 86 86 PRO PRO A . n A 1 87 PRO 87 87 87 PRO PRO A . n A 1 88 GLU 88 88 88 GLU GLU A . n A 1 89 VAL 89 89 89 VAL VAL A . n A 1 90 THR 90 90 90 THR THR A . n A 1 91 VAL 91 91 91 VAL VAL A . n A 1 92 LEU 92 92 92 LEU LEU A . n A 1 93 THR 93 93 93 THR THR A . n A 1 94 ASN 94 94 94 ASN ASN A . n A 1 95 SER 95 95 95 SER SER A . n A 1 96 PRO 96 96 96 PRO PRO A . n A 1 97 VAL 97 97 97 VAL VAL A . n A 1 98 GLU 98 98 98 GLU GLU A . n A 1 99 LEU 99 99 99 LEU LEU A . n A 1 100 ARG 100 100 100 ARG ARG A . n A 1 101 GLU 101 101 101 GLU GLU A . n A 1 102 PRO 102 102 102 PRO PRO A . n A 1 103 ASN 103 103 103 ASN ASN A . n A 1 104 VAL 104 104 104 VAL VAL A . n A 1 105 LEU 105 105 105 LEU LEU A . n A 1 106 ILE 106 106 106 ILE ILE A . n A 1 107 CYS 107 107 107 CYS CYS A . n A 1 108 PHE 108 108 108 PHE PHE A . n A 1 109 ILE 109 109 109 ILE ILE A . n A 1 110 ASP 110 110 110 ASP ASP A . n A 1 111 LYS 111 111 111 LYS LYS A . n A 1 112 PHE 112 112 112 PHE PHE A . n A 1 113 THR 113 113 113 THR THR A . n A 1 114 PRO 114 114 114 PRO PRO A . n A 1 115 PRO 115 115 115 PRO PRO A . n A 1 116 VAL 116 116 116 VAL VAL A . n A 1 117 VAL 117 117 117 VAL VAL A . n A 1 118 ASN 118 118 118 ASN ASN A . n A 1 119 VAL 119 119 119 VAL VAL A . n A 1 120 THR 120 120 120 THR THR A . n A 1 121 TRP 121 121 121 TRP TRP A . n A 1 122 LEU 122 122 122 LEU LEU A . n A 1 123 ARG 123 123 123 ARG ARG A . n A 1 124 ASN 124 124 124 ASN ASN A . n A 1 125 GLY 125 125 125 GLY GLY A . n A 1 126 LYS 126 126 126 LYS LYS A . n A 1 127 PRO 127 127 127 PRO PRO A . n A 1 128 VAL 128 128 128 VAL VAL A . n A 1 129 THR 129 129 129 THR THR A . n A 1 130 THR 130 130 130 THR THR A . n A 1 131 GLY 131 131 131 GLY GLY A . n A 1 132 VAL 132 132 132 VAL VAL A . n A 1 133 SER 133 133 133 SER SER A . n A 1 134 GLU 134 134 134 GLU GLU A . n A 1 135 THR 135 135 135 THR THR A . n A 1 136 VAL 136 136 136 VAL VAL A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 LEU 138 138 138 LEU LEU A . n A 1 139 PRO 139 139 139 PRO PRO A . n A 1 140 ARG 140 140 140 ARG ARG A . n A 1 141 GLU 141 141 141 GLU GLU A . n A 1 142 ASP 142 142 142 ASP ASP A . n A 1 143 HIS 143 143 143 HIS HIS A . n A 1 144 LEU 144 144 144 LEU LEU A . n A 1 145 PHE 145 145 145 PHE PHE A . n A 1 146 ARG 146 146 146 ARG ARG A . n A 1 147 LYS 147 147 147 LYS LYS A . n A 1 148 PHE 148 148 148 PHE PHE A . n A 1 149 HIS 149 149 149 HIS HIS A . n A 1 150 TYR 150 150 150 TYR TYR A . n A 1 151 LEU 151 151 151 LEU LEU A . n A 1 152 PRO 152 152 152 PRO PRO A . n A 1 153 PHE 153 153 153 PHE PHE A . n A 1 154 LEU 154 154 154 LEU LEU A . n A 1 155 PRO 155 155 155 PRO PRO A . n A 1 156 SER 156 156 156 SER SER A . n A 1 157 THR 157 157 157 THR THR A . n A 1 158 GLU 158 158 158 GLU GLU A . n A 1 159 ASP 159 159 159 ASP ASP A . n A 1 160 VAL 160 160 160 VAL VAL A . n A 1 161 TYR 161 161 161 TYR TYR A . n A 1 162 ASP 162 162 162 ASP ASP A . n A 1 163 CYS 163 163 163 CYS CYS A . n A 1 164 ARG 164 164 164 ARG ARG A . n A 1 165 VAL 165 165 165 VAL VAL A . n A 1 166 GLU 166 166 166 GLU GLU A . n A 1 167 HIS 167 167 167 HIS HIS A . n A 1 168 TRP 168 168 168 TRP TRP A . n A 1 169 GLY 169 169 169 GLY GLY A . n A 1 170 LEU 170 170 170 LEU LEU A . n A 1 171 ASP 171 171 171 ASP ASP A . n A 1 172 GLU 172 172 172 GLU GLU A . n A 1 173 PRO 173 173 173 PRO PRO A . n A 1 174 LEU 174 174 174 LEU LEU A . n A 1 175 LEU 175 175 175 LEU LEU A . n A 1 176 LYS 176 176 176 LYS LYS A . n A 1 177 HIS 177 177 177 HIS HIS A . n A 1 178 TRP 178 178 178 TRP TRP A . n A 1 179 GLU 179 179 179 GLU GLU A . n A 1 180 PHE 180 180 180 PHE PHE A . n A 1 181 ASP 181 181 181 ASP ASP A . n A 1 182 ALA 182 182 182 ALA ALA A . n B 2 1 GLY 1 1 ? ? ? B . n B 2 2 ASP 2 2 2 ASP ASP B . n B 2 3 THR 3 3 3 THR THR B . n B 2 4 ARG 4 4 4 ARG ARG B . n B 2 5 PRO 5 5 5 PRO PRO B . n B 2 6 ARG 6 6 6 ARG ARG B . n B 2 7 PHE 7 7 7 PHE PHE B . n B 2 8 LEU 8 8 8 LEU LEU B . n B 2 9 GLN 9 9 9 GLN GLN B . n B 2 10 GLN 10 10 10 GLN GLN B . n B 2 11 ASP 11 11 11 ASP ASP B . n B 2 12 LYS 12 12 12 LYS LYS B . n B 2 13 TYR 13 13 13 TYR TYR B . n B 2 14 GLU 14 14 14 GLU GLU B . n B 2 15 CYS 15 15 15 CYS CYS B . n B 2 16 HIS 16 16 16 HIS HIS B . n B 2 17 PHE 17 17 17 PHE PHE B . n B 2 18 PHE 18 18 18 PHE PHE B . n B 2 19 ASN 19 19 19 ASN ASN B . n B 2 20 GLY 20 20 20 GLY GLY B . n B 2 21 THR 21 21 21 THR THR B . n B 2 22 GLU 22 22 22 GLU GLU B . n B 2 23 ARG 23 23 23 ARG ARG B . n B 2 24 VAL 24 24 24 VAL VAL B . n B 2 25 ARG 25 25 25 ARG ARG B . n B 2 26 PHE 26 26 26 PHE PHE B . n B 2 27 LEU 27 27 27 LEU LEU B . n B 2 28 HIS 28 28 28 HIS HIS B . n B 2 29 ARG 29 29 29 ARG ARG B . n B 2 30 ASP 30 30 30 ASP ASP B . n B 2 31 ILE 31 31 31 ILE ILE B . n B 2 32 TYR 32 32 32 TYR TYR B . n B 2 33 ASN 33 33 33 ASN ASN B . n B 2 34 GLN 34 34 34 GLN GLN B . n B 2 35 GLU 35 35 35 GLU GLU B . n B 2 36 GLU 36 36 36 GLU GLU B . n B 2 37 ASP 37 37 37 ASP ASP B . n B 2 38 LEU 38 38 38 LEU LEU B . n B 2 39 ARG 39 39 39 ARG ARG B . n B 2 40 PHE 40 40 40 PHE PHE B . n B 2 41 ASP 41 41 41 ASP ASP B . n B 2 42 SER 42 42 42 SER SER B . n B 2 43 ASP 43 43 43 ASP ASP B . n B 2 44 VAL 44 44 44 VAL VAL B . n B 2 45 GLY 45 45 45 GLY GLY B . n B 2 46 GLU 46 46 46 GLU GLU B . n B 2 47 TYR 47 47 47 TYR TYR B . n B 2 48 ARG 48 48 48 ARG ARG B . n B 2 49 ALA 49 49 49 ALA ALA B . n B 2 50 VAL 50 50 50 VAL VAL B . n B 2 51 THR 51 51 51 THR THR B . n B 2 52 GLU 52 52 52 GLU GLU B . n B 2 53 LEU 53 53 53 LEU LEU B . n B 2 54 GLY 54 54 54 GLY GLY B . n B 2 55 ARG 55 55 55 ARG ARG B . n B 2 56 PRO 56 56 56 PRO PRO B . n B 2 57 ASP 57 57 57 ASP ASP B . n B 2 58 ALA 58 58 58 ALA ALA B . n B 2 59 GLU 59 59 59 GLU GLU B . n B 2 60 TYR 60 60 60 TYR TYR B . n B 2 61 TRP 61 61 61 TRP TRP B . n B 2 62 ASN 62 62 62 ASN ASN B . n B 2 63 SER 63 63 63 SER SER B . n B 2 64 GLN 64 64 64 GLN GLN B . n B 2 65 LYS 65 65 65 LYS LYS B . n B 2 66 ASP 66 66 66 ASP ASP B . n B 2 67 PHE 67 67 67 PHE PHE B . n B 2 68 LEU 68 68 68 LEU LEU B . n B 2 69 GLU 69 69 69 GLU GLU B . n B 2 70 ASP 70 70 70 ASP ASP B . n B 2 71 ARG 71 71 71 ARG ARG B . n B 2 72 ARG 72 72 72 ARG ARG B . n B 2 73 ALA 73 73 73 ALA ALA B . n B 2 74 ALA 74 74 74 ALA ALA B . n B 2 75 VAL 75 75 75 VAL VAL B . n B 2 76 ASP 76 76 76 ASP ASP B . n B 2 77 THR 77 77 77 THR THR B . n B 2 78 TYR 78 78 78 TYR TYR B . n B 2 79 CYS 79 79 79 CYS CYS B . n B 2 80 ARG 80 80 80 ARG ARG B . n B 2 81 HIS 81 81 81 HIS HIS B . n B 2 82 ASN 82 82 82 ASN ASN B . n B 2 83 TYR 83 83 83 TYR TYR B . n B 2 84 GLY 84 84 84 GLY GLY B . n B 2 85 VAL 85 85 85 VAL VAL B . n B 2 86 GLY 86 86 86 GLY GLY B . n B 2 87 GLU 87 87 87 GLU GLU B . n B 2 88 SER 88 88 88 SER SER B . n B 2 89 PHE 89 89 89 PHE PHE B . n B 2 90 THR 90 90 90 THR THR B . n B 2 91 VAL 91 91 91 VAL VAL B . n B 2 92 GLN 92 92 92 GLN GLN B . n B 2 93 ARG 93 93 93 ARG ARG B . n B 2 94 ARG 94 94 94 ARG ARG B . n B 2 95 VAL 95 95 95 VAL VAL B . n B 2 96 GLU 96 96 96 GLU GLU B . n B 2 97 PRO 97 97 97 PRO PRO B . n B 2 98 LYS 98 98 98 LYS LYS B . n B 2 99 VAL 99 99 99 VAL VAL B . n B 2 100 THR 100 100 100 THR THR B . n B 2 101 VAL 101 101 101 VAL VAL B . n B 2 102 TYR 102 102 102 TYR TYR B . n B 2 103 PRO 103 103 103 PRO PRO B . n B 2 104 ALA 104 104 104 ALA ALA B . n B 2 105 ARG 105 105 105 ARG ARG B . n B 2 106 THR 106 106 106 THR THR B . n B 2 107 GLN 107 107 107 GLN GLN B . n B 2 108 THR 108 108 108 THR THR B . n B 2 109 LEU 109 109 109 LEU LEU B . n B 2 110 GLN 110 110 110 GLN GLN B . n B 2 111 HIS 111 111 111 HIS HIS B . n B 2 112 HIS 112 112 112 HIS HIS B . n B 2 113 ASN 113 113 113 ASN ASN B . n B 2 114 LEU 114 114 114 LEU LEU B . n B 2 115 LEU 115 115 115 LEU LEU B . n B 2 116 VAL 116 116 116 VAL VAL B . n B 2 117 CYS 117 117 117 CYS CYS B . n B 2 118 SER 118 118 118 SER SER B . n B 2 119 VAL 119 119 119 VAL VAL B . n B 2 120 ASN 120 120 120 ASN ASN B . n B 2 121 GLY 121 121 121 GLY GLY B . n B 2 122 PHE 122 122 122 PHE PHE B . n B 2 123 TYR 123 123 123 TYR TYR B . n B 2 124 PRO 124 124 124 PRO PRO B . n B 2 125 GLY 125 125 125 GLY GLY B . n B 2 126 SER 126 126 126 SER SER B . n B 2 127 ILE 127 127 127 ILE ILE B . n B 2 128 GLU 128 128 128 GLU GLU B . n B 2 129 VAL 129 129 129 VAL VAL B . n B 2 130 ARG 130 130 130 ARG ARG B . n B 2 131 TRP 131 131 131 TRP TRP B . n B 2 132 PHE 132 132 132 PHE PHE B . n B 2 133 ARG 133 133 133 ARG ARG B . n B 2 134 ASN 134 134 134 ASN ASN B . n B 2 135 SER 135 135 135 SER SER B . n B 2 136 GLN 136 136 136 GLN GLN B . n B 2 137 GLU 137 137 137 GLU GLU B . n B 2 138 GLU 138 138 138 GLU GLU B . n B 2 139 LYS 139 139 139 LYS LYS B . n B 2 140 ALA 140 140 140 ALA ALA B . n B 2 141 GLY 141 141 141 GLY GLY B . n B 2 142 VAL 142 142 142 VAL VAL B . n B 2 143 VAL 143 143 143 VAL VAL B . n B 2 144 SER 144 144 144 SER SER B . n B 2 145 THR 145 145 145 THR THR B . n B 2 146 GLY 146 146 146 GLY GLY B . n B 2 147 LEU 147 147 147 LEU LEU B . n B 2 148 ILE 148 148 148 ILE ILE B . n B 2 149 GLN 149 149 149 GLN GLN B . n B 2 150 ASN 150 150 150 ASN ASN B . n B 2 151 GLY 151 151 151 GLY GLY B . n B 2 152 ASP 152 152 152 ASP ASP B . n B 2 153 TRP 153 153 153 TRP TRP B . n B 2 154 THR 154 154 154 THR THR B . n B 2 155 PHE 155 155 155 PHE PHE B . n B 2 156 GLN 156 156 156 GLN GLN B . n B 2 157 THR 157 157 157 THR THR B . n B 2 158 LEU 158 158 158 LEU LEU B . n B 2 159 VAL 159 159 159 VAL VAL B . n B 2 160 MET 160 160 160 MET MET B . n B 2 161 LEU 161 161 161 LEU LEU B . n B 2 162 GLU 162 162 162 GLU GLU B . n B 2 163 THR 163 163 163 THR THR B . n B 2 164 VAL 164 164 164 VAL VAL B . n B 2 165 PRO 165 165 165 PRO PRO B . n B 2 166 ARG 166 166 166 ARG ARG B . n B 2 167 SER 167 167 167 SER SER B . n B 2 168 GLY 168 168 168 GLY GLY B . n B 2 169 GLU 169 169 169 GLU GLU B . n B 2 170 VAL 170 170 170 VAL VAL B . n B 2 171 TYR 171 171 171 TYR TYR B . n B 2 172 THR 172 172 172 THR THR B . n B 2 173 CYS 173 173 173 CYS CYS B . n B 2 174 GLN 174 174 174 GLN GLN B . n B 2 175 VAL 175 175 175 VAL VAL B . n B 2 176 GLU 176 176 176 GLU GLU B . n B 2 177 HIS 177 177 177 HIS HIS B . n B 2 178 PRO 178 178 178 PRO PRO B . n B 2 179 SER 179 179 179 SER SER B . n B 2 180 VAL 180 180 180 VAL VAL B . n B 2 181 THR 181 181 181 THR THR B . n B 2 182 SER 182 182 182 SER SER B . n B 2 183 PRO 183 183 183 PRO PRO B . n B 2 184 LEU 184 184 184 LEU LEU B . n B 2 185 THR 185 185 185 THR THR B . n B 2 186 VAL 186 186 186 VAL VAL B . n B 2 187 GLU 187 187 187 GLU GLU B . n B 2 188 TRP 188 188 188 TRP TRP B . n B 2 189 ARG 189 189 189 ARG ARG B . n B 2 190 ALA 190 190 190 ALA ALA B . n C 3 1 GLY 1 628 628 GLY GLY C . n C 3 2 GLY 2 629 629 GLY GLY C . n C 3 3 VAL 3 630 630 VAL VAL C . n C 3 4 TYR 4 631 631 TYR TYR C . n C 3 5 HIS 5 632 632 HIS HIS C . n C 3 6 PHE 6 633 633 PHE PHE C . n C 3 7 VAL 7 634 634 VAL VAL C . n C 3 8 LYS 8 635 635 LYS LYS C . n C 3 9 LYS 9 636 636 LYS LYS C . n C 3 10 HIS 10 637 637 HIS HIS C . n C 3 11 VAL 11 638 638 VAL VAL C . n C 3 12 HIS 12 639 639 HIS HIS C . n C 3 13 GLU 13 640 640 GLU GLU C . n C 3 14 SER 14 641 641 SER SER C . n D 1 1 ILE 1 1 ? ? ? D . n D 1 2 LYS 2 2 ? ? ? D . n D 1 3 GLU 3 3 3 GLU GLU D . n D 1 4 GLU 4 4 4 GLU GLU D . n D 1 5 HIS 5 5 5 HIS HIS D . n D 1 6 VAL 6 6 6 VAL VAL D . n D 1 7 ILE 7 7 7 ILE ILE D . n D 1 8 ILE 8 8 8 ILE ILE D . n D 1 9 GLN 9 9 9 GLN GLN D . n D 1 10 ALA 10 10 10 ALA ALA D . n D 1 11 GLU 11 11 11 GLU GLU D . n D 1 12 PHE 12 12 12 PHE PHE D . n D 1 13 TYR 13 13 13 TYR TYR D . n D 1 14 LEU 14 14 14 LEU LEU D . n D 1 15 ASN 15 15 15 ASN ASN D . n D 1 16 PRO 16 16 16 PRO PRO D . n D 1 17 ASP 17 17 17 ASP ASP D . n D 1 18 GLN 18 18 18 GLN GLN D . n D 1 19 SER 19 19 19 SER SER D . n D 1 20 GLY 20 20 20 GLY GLY D . n D 1 21 GLU 21 21 21 GLU GLU D . n D 1 22 PHE 22 22 22 PHE PHE D . n D 1 23 MET 23 23 23 MET MET D . n D 1 24 PHE 24 24 24 PHE PHE D . n D 1 25 ASP 25 25 25 ASP ASP D . n D 1 26 PHE 26 26 26 PHE PHE D . n D 1 27 ASP 27 27 27 ASP ASP D . n D 1 28 GLY 28 28 28 GLY GLY D . n D 1 29 ASP 29 29 29 ASP ASP D . n D 1 30 GLU 30 30 30 GLU GLU D . n D 1 31 ILE 31 31 31 ILE ILE D . n D 1 32 PHE 32 32 32 PHE PHE D . n D 1 33 HIS 33 33 33 HIS HIS D . n D 1 34 VAL 34 34 34 VAL VAL D . n D 1 35 ASP 35 35 35 ASP ASP D . n D 1 36 MET 36 36 36 MET MET D . n D 1 37 ALA 37 37 37 ALA ALA D . n D 1 38 LYS 38 38 38 LYS LYS D . n D 1 39 LYS 39 39 39 LYS LYS D . n D 1 40 GLU 40 40 40 GLU GLU D . n D 1 41 THR 41 41 41 THR THR D . n D 1 42 VAL 42 42 42 VAL VAL D . n D 1 43 TRP 43 43 43 TRP TRP D . n D 1 44 ARG 44 44 44 ARG ARG D . n D 1 45 LEU 45 45 45 LEU LEU D . n D 1 46 GLU 46 46 46 GLU GLU D . n D 1 47 GLU 47 47 47 GLU GLU D . n D 1 48 PHE 48 48 48 PHE PHE D . n D 1 49 GLY 49 49 49 GLY GLY D . n D 1 50 ARG 50 50 50 ARG ARG D . n D 1 51 PHE 51 51 51 PHE PHE D . n D 1 52 ALA 52 52 52 ALA ALA D . n D 1 53 SER 53 53 53 SER SER D . n D 1 54 PHE 54 54 54 PHE PHE D . n D 1 55 GLU 55 55 55 GLU GLU D . n D 1 56 ALA 56 56 56 ALA ALA D . n D 1 57 GLN 57 57 57 GLN GLN D . n D 1 58 GLY 58 58 58 GLY GLY D . n D 1 59 ALA 59 59 59 ALA ALA D . n D 1 60 LEU 60 60 60 LEU LEU D . n D 1 61 ALA 61 61 61 ALA ALA D . n D 1 62 ASN 62 62 62 ASN ASN D . n D 1 63 ILE 63 63 63 ILE ILE D . n D 1 64 ALA 64 64 64 ALA ALA D . n D 1 65 VAL 65 65 65 VAL VAL D . n D 1 66 ASP 66 66 66 ASP ASP D . n D 1 67 LYS 67 67 67 LYS LYS D . n D 1 68 ALA 68 68 68 ALA ALA D . n D 1 69 ASN 69 69 69 ASN ASN D . n D 1 70 LEU 70 70 70 LEU LEU D . n D 1 71 GLU 71 71 71 GLU GLU D . n D 1 72 ILE 72 72 72 ILE ILE D . n D 1 73 MET 73 73 73 MET MET D . n D 1 74 THR 74 74 74 THR THR D . n D 1 75 LYS 75 75 75 LYS LYS D . n D 1 76 ARG 76 76 76 ARG ARG D . n D 1 77 SER 77 77 77 SER SER D . n D 1 78 ASN 78 78 78 ASN ASN D . n D 1 79 TYR 79 79 79 TYR TYR D . n D 1 80 THR 80 80 80 THR THR D . n D 1 81 PRO 81 81 81 PRO PRO D . n D 1 82 ILE 82 82 82 ILE ILE D . n D 1 83 THR 83 83 83 THR THR D . n D 1 84 ASN 84 84 84 ASN ASN D . n D 1 85 VAL 85 85 85 VAL VAL D . n D 1 86 PRO 86 86 86 PRO PRO D . n D 1 87 PRO 87 87 87 PRO PRO D . n D 1 88 GLU 88 88 88 GLU GLU D . n D 1 89 VAL 89 89 89 VAL VAL D . n D 1 90 THR 90 90 90 THR THR D . n D 1 91 VAL 91 91 91 VAL VAL D . n D 1 92 LEU 92 92 92 LEU LEU D . n D 1 93 THR 93 93 93 THR THR D . n D 1 94 ASN 94 94 94 ASN ASN D . n D 1 95 SER 95 95 95 SER SER D . n D 1 96 PRO 96 96 96 PRO PRO D . n D 1 97 VAL 97 97 97 VAL VAL D . n D 1 98 GLU 98 98 98 GLU GLU D . n D 1 99 LEU 99 99 99 LEU LEU D . n D 1 100 ARG 100 100 100 ARG ARG D . n D 1 101 GLU 101 101 101 GLU GLU D . n D 1 102 PRO 102 102 102 PRO PRO D . n D 1 103 ASN 103 103 103 ASN ASN D . n D 1 104 VAL 104 104 104 VAL VAL D . n D 1 105 LEU 105 105 105 LEU LEU D . n D 1 106 ILE 106 106 106 ILE ILE D . n D 1 107 CYS 107 107 107 CYS CYS D . n D 1 108 PHE 108 108 108 PHE PHE D . n D 1 109 ILE 109 109 109 ILE ILE D . n D 1 110 ASP 110 110 110 ASP ASP D . n D 1 111 LYS 111 111 111 LYS LYS D . n D 1 112 PHE 112 112 112 PHE PHE D . n D 1 113 THR 113 113 113 THR THR D . n D 1 114 PRO 114 114 114 PRO PRO D . n D 1 115 PRO 115 115 115 PRO PRO D . n D 1 116 VAL 116 116 116 VAL VAL D . n D 1 117 VAL 117 117 117 VAL VAL D . n D 1 118 ASN 118 118 118 ASN ASN D . n D 1 119 VAL 119 119 119 VAL VAL D . n D 1 120 THR 120 120 120 THR THR D . n D 1 121 TRP 121 121 121 TRP TRP D . n D 1 122 LEU 122 122 122 LEU LEU D . n D 1 123 ARG 123 123 123 ARG ARG D . n D 1 124 ASN 124 124 124 ASN ASN D . n D 1 125 GLY 125 125 125 GLY GLY D . n D 1 126 LYS 126 126 126 LYS LYS D . n D 1 127 PRO 127 127 127 PRO PRO D . n D 1 128 VAL 128 128 128 VAL VAL D . n D 1 129 THR 129 129 129 THR THR D . n D 1 130 THR 130 130 130 THR THR D . n D 1 131 GLY 131 131 131 GLY GLY D . n D 1 132 VAL 132 132 132 VAL VAL D . n D 1 133 SER 133 133 133 SER SER D . n D 1 134 GLU 134 134 134 GLU GLU D . n D 1 135 THR 135 135 135 THR THR D . n D 1 136 VAL 136 136 136 VAL VAL D . n D 1 137 PHE 137 137 137 PHE PHE D . n D 1 138 LEU 138 138 138 LEU LEU D . n D 1 139 PRO 139 139 139 PRO PRO D . n D 1 140 ARG 140 140 140 ARG ARG D . n D 1 141 GLU 141 141 141 GLU GLU D . n D 1 142 ASP 142 142 142 ASP ASP D . n D 1 143 HIS 143 143 143 HIS HIS D . n D 1 144 LEU 144 144 144 LEU LEU D . n D 1 145 PHE 145 145 145 PHE PHE D . n D 1 146 ARG 146 146 146 ARG ARG D . n D 1 147 LYS 147 147 147 LYS LYS D . n D 1 148 PHE 148 148 148 PHE PHE D . n D 1 149 HIS 149 149 149 HIS HIS D . n D 1 150 TYR 150 150 150 TYR TYR D . n D 1 151 LEU 151 151 151 LEU LEU D . n D 1 152 PRO 152 152 152 PRO PRO D . n D 1 153 PHE 153 153 153 PHE PHE D . n D 1 154 LEU 154 154 154 LEU LEU D . n D 1 155 PRO 155 155 155 PRO PRO D . n D 1 156 SER 156 156 156 SER SER D . n D 1 157 THR 157 157 157 THR THR D . n D 1 158 GLU 158 158 158 GLU GLU D . n D 1 159 ASP 159 159 159 ASP ASP D . n D 1 160 VAL 160 160 160 VAL VAL D . n D 1 161 TYR 161 161 161 TYR TYR D . n D 1 162 ASP 162 162 162 ASP ASP D . n D 1 163 CYS 163 163 163 CYS CYS D . n D 1 164 ARG 164 164 164 ARG ARG D . n D 1 165 VAL 165 165 165 VAL VAL D . n D 1 166 GLU 166 166 166 GLU GLU D . n D 1 167 HIS 167 167 167 HIS HIS D . n D 1 168 TRP 168 168 168 TRP TRP D . n D 1 169 GLY 169 169 169 GLY GLY D . n D 1 170 LEU 170 170 170 LEU LEU D . n D 1 171 ASP 171 171 171 ASP ASP D . n D 1 172 GLU 172 172 172 GLU GLU D . n D 1 173 PRO 173 173 173 PRO PRO D . n D 1 174 LEU 174 174 174 LEU LEU D . n D 1 175 LEU 175 175 175 LEU LEU D . n D 1 176 LYS 176 176 176 LYS LYS D . n D 1 177 HIS 177 177 177 HIS HIS D . n D 1 178 TRP 178 178 178 TRP TRP D . n D 1 179 GLU 179 179 179 GLU GLU D . n D 1 180 PHE 180 180 180 PHE PHE D . n D 1 181 ASP 181 181 181 ASP ASP D . n D 1 182 ALA 182 182 182 ALA ALA D . n E 2 1 GLY 1 1 ? ? ? E . n E 2 2 ASP 2 2 2 ASP ASP E . n E 2 3 THR 3 3 3 THR THR E . n E 2 4 ARG 4 4 4 ARG ARG E . n E 2 5 PRO 5 5 5 PRO PRO E . n E 2 6 ARG 6 6 6 ARG ARG E . n E 2 7 PHE 7 7 7 PHE PHE E . n E 2 8 LEU 8 8 8 LEU LEU E . n E 2 9 GLN 9 9 9 GLN GLN E . n E 2 10 GLN 10 10 10 GLN GLN E . n E 2 11 ASP 11 11 11 ASP ASP E . n E 2 12 LYS 12 12 12 LYS LYS E . n E 2 13 TYR 13 13 13 TYR TYR E . n E 2 14 GLU 14 14 14 GLU GLU E . n E 2 15 CYS 15 15 15 CYS CYS E . n E 2 16 HIS 16 16 16 HIS HIS E . n E 2 17 PHE 17 17 17 PHE PHE E . n E 2 18 PHE 18 18 18 PHE PHE E . n E 2 19 ASN 19 19 19 ASN ASN E . n E 2 20 GLY 20 20 20 GLY GLY E . n E 2 21 THR 21 21 21 THR THR E . n E 2 22 GLU 22 22 22 GLU GLU E . n E 2 23 ARG 23 23 23 ARG ARG E . n E 2 24 VAL 24 24 24 VAL VAL E . n E 2 25 ARG 25 25 25 ARG ARG E . n E 2 26 PHE 26 26 26 PHE PHE E . n E 2 27 LEU 27 27 27 LEU LEU E . n E 2 28 HIS 28 28 28 HIS HIS E . n E 2 29 ARG 29 29 29 ARG ARG E . n E 2 30 ASP 30 30 30 ASP ASP E . n E 2 31 ILE 31 31 31 ILE ILE E . n E 2 32 TYR 32 32 32 TYR TYR E . n E 2 33 ASN 33 33 33 ASN ASN E . n E 2 34 GLN 34 34 34 GLN GLN E . n E 2 35 GLU 35 35 35 GLU GLU E . n E 2 36 GLU 36 36 36 GLU GLU E . n E 2 37 ASP 37 37 37 ASP ASP E . n E 2 38 LEU 38 38 38 LEU LEU E . n E 2 39 ARG 39 39 39 ARG ARG E . n E 2 40 PHE 40 40 40 PHE PHE E . n E 2 41 ASP 41 41 41 ASP ASP E . n E 2 42 SER 42 42 42 SER SER E . n E 2 43 ASP 43 43 43 ASP ASP E . n E 2 44 VAL 44 44 44 VAL VAL E . n E 2 45 GLY 45 45 45 GLY GLY E . n E 2 46 GLU 46 46 46 GLU GLU E . n E 2 47 TYR 47 47 47 TYR TYR E . n E 2 48 ARG 48 48 48 ARG ARG E . n E 2 49 ALA 49 49 49 ALA ALA E . n E 2 50 VAL 50 50 50 VAL VAL E . n E 2 51 THR 51 51 51 THR THR E . n E 2 52 GLU 52 52 52 GLU GLU E . n E 2 53 LEU 53 53 53 LEU LEU E . n E 2 54 GLY 54 54 54 GLY GLY E . n E 2 55 ARG 55 55 55 ARG ARG E . n E 2 56 PRO 56 56 56 PRO PRO E . n E 2 57 ASP 57 57 57 ASP ASP E . n E 2 58 ALA 58 58 58 ALA ALA E . n E 2 59 GLU 59 59 59 GLU GLU E . n E 2 60 TYR 60 60 60 TYR TYR E . n E 2 61 TRP 61 61 61 TRP TRP E . n E 2 62 ASN 62 62 62 ASN ASN E . n E 2 63 SER 63 63 63 SER SER E . n E 2 64 GLN 64 64 64 GLN GLN E . n E 2 65 LYS 65 65 65 LYS LYS E . n E 2 66 ASP 66 66 66 ASP ASP E . n E 2 67 PHE 67 67 67 PHE PHE E . n E 2 68 LEU 68 68 68 LEU LEU E . n E 2 69 GLU 69 69 69 GLU GLU E . n E 2 70 ASP 70 70 70 ASP ASP E . n E 2 71 ARG 71 71 71 ARG ARG E . n E 2 72 ARG 72 72 72 ARG ARG E . n E 2 73 ALA 73 73 73 ALA ALA E . n E 2 74 ALA 74 74 74 ALA ALA E . n E 2 75 VAL 75 75 75 VAL VAL E . n E 2 76 ASP 76 76 76 ASP ASP E . n E 2 77 THR 77 77 77 THR THR E . n E 2 78 TYR 78 78 78 TYR TYR E . n E 2 79 CYS 79 79 79 CYS CYS E . n E 2 80 ARG 80 80 80 ARG ARG E . n E 2 81 HIS 81 81 81 HIS HIS E . n E 2 82 ASN 82 82 82 ASN ASN E . n E 2 83 TYR 83 83 83 TYR TYR E . n E 2 84 GLY 84 84 84 GLY GLY E . n E 2 85 VAL 85 85 85 VAL VAL E . n E 2 86 GLY 86 86 86 GLY GLY E . n E 2 87 GLU 87 87 87 GLU GLU E . n E 2 88 SER 88 88 88 SER SER E . n E 2 89 PHE 89 89 89 PHE PHE E . n E 2 90 THR 90 90 90 THR THR E . n E 2 91 VAL 91 91 91 VAL VAL E . n E 2 92 GLN 92 92 92 GLN GLN E . n E 2 93 ARG 93 93 93 ARG ARG E . n E 2 94 ARG 94 94 94 ARG ARG E . n E 2 95 VAL 95 95 95 VAL VAL E . n E 2 96 GLU 96 96 96 GLU GLU E . n E 2 97 PRO 97 97 97 PRO PRO E . n E 2 98 LYS 98 98 98 LYS LYS E . n E 2 99 VAL 99 99 99 VAL VAL E . n E 2 100 THR 100 100 100 THR THR E . n E 2 101 VAL 101 101 101 VAL VAL E . n E 2 102 TYR 102 102 102 TYR TYR E . n E 2 103 PRO 103 103 103 PRO PRO E . n E 2 104 ALA 104 104 104 ALA ALA E . n E 2 105 ARG 105 105 105 ARG ARG E . n E 2 106 THR 106 106 106 THR THR E . n E 2 107 GLN 107 107 107 GLN GLN E . n E 2 108 THR 108 108 108 THR THR E . n E 2 109 LEU 109 109 109 LEU LEU E . n E 2 110 GLN 110 110 110 GLN GLN E . n E 2 111 HIS 111 111 111 HIS HIS E . n E 2 112 HIS 112 112 112 HIS HIS E . n E 2 113 ASN 113 113 113 ASN ASN E . n E 2 114 LEU 114 114 114 LEU LEU E . n E 2 115 LEU 115 115 115 LEU LEU E . n E 2 116 VAL 116 116 116 VAL VAL E . n E 2 117 CYS 117 117 117 CYS CYS E . n E 2 118 SER 118 118 118 SER SER E . n E 2 119 VAL 119 119 119 VAL VAL E . n E 2 120 ASN 120 120 120 ASN ASN E . n E 2 121 GLY 121 121 121 GLY GLY E . n E 2 122 PHE 122 122 122 PHE PHE E . n E 2 123 TYR 123 123 123 TYR TYR E . n E 2 124 PRO 124 124 124 PRO PRO E . n E 2 125 GLY 125 125 125 GLY GLY E . n E 2 126 SER 126 126 126 SER SER E . n E 2 127 ILE 127 127 127 ILE ILE E . n E 2 128 GLU 128 128 128 GLU GLU E . n E 2 129 VAL 129 129 129 VAL VAL E . n E 2 130 ARG 130 130 130 ARG ARG E . n E 2 131 TRP 131 131 131 TRP TRP E . n E 2 132 PHE 132 132 132 PHE PHE E . n E 2 133 ARG 133 133 133 ARG ARG E . n E 2 134 ASN 134 134 134 ASN ASN E . n E 2 135 SER 135 135 135 SER SER E . n E 2 136 GLN 136 136 136 GLN GLN E . n E 2 137 GLU 137 137 137 GLU GLU E . n E 2 138 GLU 138 138 138 GLU GLU E . n E 2 139 LYS 139 139 139 LYS LYS E . n E 2 140 ALA 140 140 140 ALA ALA E . n E 2 141 GLY 141 141 141 GLY GLY E . n E 2 142 VAL 142 142 142 VAL VAL E . n E 2 143 VAL 143 143 143 VAL VAL E . n E 2 144 SER 144 144 144 SER SER E . n E 2 145 THR 145 145 145 THR THR E . n E 2 146 GLY 146 146 146 GLY GLY E . n E 2 147 LEU 147 147 147 LEU LEU E . n E 2 148 ILE 148 148 148 ILE ILE E . n E 2 149 GLN 149 149 149 GLN GLN E . n E 2 150 ASN 150 150 150 ASN ASN E . n E 2 151 GLY 151 151 151 GLY GLY E . n E 2 152 ASP 152 152 152 ASP ASP E . n E 2 153 TRP 153 153 153 TRP TRP E . n E 2 154 THR 154 154 154 THR THR E . n E 2 155 PHE 155 155 155 PHE PHE E . n E 2 156 GLN 156 156 156 GLN GLN E . n E 2 157 THR 157 157 157 THR THR E . n E 2 158 LEU 158 158 158 LEU LEU E . n E 2 159 VAL 159 159 159 VAL VAL E . n E 2 160 MET 160 160 160 MET MET E . n E 2 161 LEU 161 161 161 LEU LEU E . n E 2 162 GLU 162 162 162 GLU GLU E . n E 2 163 THR 163 163 163 THR THR E . n E 2 164 VAL 164 164 164 VAL VAL E . n E 2 165 PRO 165 165 165 PRO PRO E . n E 2 166 ARG 166 166 166 ARG ARG E . n E 2 167 SER 167 167 167 SER SER E . n E 2 168 GLY 168 168 168 GLY GLY E . n E 2 169 GLU 169 169 169 GLU GLU E . n E 2 170 VAL 170 170 170 VAL VAL E . n E 2 171 TYR 171 171 171 TYR TYR E . n E 2 172 THR 172 172 172 THR THR E . n E 2 173 CYS 173 173 173 CYS CYS E . n E 2 174 GLN 174 174 174 GLN GLN E . n E 2 175 VAL 175 175 175 VAL VAL E . n E 2 176 GLU 176 176 176 GLU GLU E . n E 2 177 HIS 177 177 177 HIS HIS E . n E 2 178 PRO 178 178 178 PRO PRO E . n E 2 179 SER 179 179 179 SER SER E . n E 2 180 VAL 180 180 180 VAL VAL E . n E 2 181 THR 181 181 181 THR THR E . n E 2 182 SER 182 182 182 SER SER E . n E 2 183 PRO 183 183 183 PRO PRO E . n E 2 184 LEU 184 184 184 LEU LEU E . n E 2 185 THR 185 185 185 THR THR E . n E 2 186 VAL 186 186 186 VAL VAL E . n E 2 187 GLU 187 187 187 GLU GLU E . n E 2 188 TRP 188 188 188 TRP TRP E . n E 2 189 ARG 189 189 189 ARG ARG E . n E 2 190 ALA 190 190 190 ALA ALA E . n F 3 1 GLY 1 628 628 GLY GLY F . n F 3 2 GLY 2 629 629 GLY GLY F . n F 3 3 VAL 3 630 630 VAL VAL F . n F 3 4 TYR 4 631 631 TYR TYR F . n F 3 5 HIS 5 632 632 HIS HIS F . n F 3 6 PHE 6 633 633 PHE PHE F . n F 3 7 VAL 7 634 634 VAL VAL F . n F 3 8 LYS 8 635 635 LYS LYS F . n F 3 9 LYS 9 636 636 LYS LYS F . n F 3 10 HIS 10 637 637 HIS HIS F . n F 3 11 VAL 11 638 638 VAL VAL F . n F 3 12 HIS 12 639 639 HIS HIS F . n F 3 13 GLU 13 640 640 GLU GLU F . n F 3 14 SER 14 641 641 SER SER F . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code G 4 NAG 1 1183 1183 NAG NAG A . H 4 NAG 2 1184 1184 NAG NAG A . I 4 NAG 1 1185 1185 NAG NAG A . J 4 NAG 1 1183 1183 NAG NAG D . K 4 NAG 1 1184 1184 NAG NAG D . L 5 HOH 1 2001 2001 HOH HOH A . L 5 HOH 2 2002 2002 HOH HOH A . L 5 HOH 3 2003 2003 HOH HOH A . L 5 HOH 4 2004 2004 HOH HOH A . L 5 HOH 5 2005 2005 HOH HOH A . L 5 HOH 6 2006 2006 HOH HOH A . L 5 HOH 7 2007 2007 HOH HOH A . L 5 HOH 8 2008 2008 HOH HOH A . L 5 HOH 9 2009 2009 HOH HOH A . L 5 HOH 10 2010 2010 HOH HOH A . L 5 HOH 11 2011 2011 HOH HOH A . L 5 HOH 12 2012 2012 HOH HOH A . M 5 HOH 1 2001 2001 HOH HOH B . M 5 HOH 2 2002 2002 HOH HOH B . M 5 HOH 3 2003 2003 HOH HOH B . M 5 HOH 4 2004 2004 HOH HOH B . M 5 HOH 5 2005 2005 HOH HOH B . M 5 HOH 6 2006 2006 HOH HOH B . M 5 HOH 7 2007 2007 HOH HOH B . M 5 HOH 8 2008 2008 HOH HOH B . N 5 HOH 1 2001 2001 HOH HOH D . N 5 HOH 2 2002 2002 HOH HOH D . O 5 HOH 1 2001 2001 HOH HOH E . O 5 HOH 2 2002 2002 HOH HOH E . O 5 HOH 3 2003 2003 HOH HOH E . O 5 HOH 4 2004 2004 HOH HOH E . O 5 HOH 5 2005 2005 HOH HOH E . O 5 HOH 6 2006 2006 HOH HOH E . O 5 HOH 7 2007 2007 HOH HOH E . O 5 HOH 8 2008 2008 HOH HOH E . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 78 A ASN 78 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 118 A ASN 118 ? ASN 'GLYCOSYLATION SITE' 3 D ASN 78 D ASN 78 ? ASN 'GLYCOSYLATION SITE' 4 D ASN 118 D ASN 118 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA trimeric 3 2 author_and_software_defined_assembly PISA trimeric 3 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,B,C,G,H,I,L,M 2 1 D,E,F,J,K,N,O # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 8020 ? 1 MORE -21.0 ? 1 'SSA (A^2)' 18360 ? 2 'ABSA (A^2)' 7650 ? 2 MORE -30.2 ? 2 'SSA (A^2)' 18400 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2002-10-03 2 'Structure model' 1 1 2011-09-28 3 'Structure model' 1 2 2012-06-27 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' Advisory 2 2 'Structure model' 'Atomic model' 3 2 'Structure model' 'Derived calculations' 4 2 'Structure model' 'Non-polymer description' 5 2 'Structure model' Other 6 2 'Structure model' 'Refinement description' 7 2 'Structure model' 'Version format compliance' 8 3 'Structure model' Other # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal CNS refinement 1.0 ? 1 DENZO 'data reduction' . ? 2 SCALEPACK 'data scaling' . ? 3 AMoRE phasing . ? 4 # _pdbx_database_remark.id 700 _pdbx_database_remark.text ; SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED. ; # _pdbx_entry_details.entry_id 1H15 _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ? _pdbx_entry_details.sequence_details ;RESIDUES 26-207 OF DATABASE SEQUENCE RESIDUES 30-219 OF DATABASE SEQUENCE ; # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 N _pdbx_validate_rmsd_angle.auth_asym_id_1 A _pdbx_validate_rmsd_angle.auth_comp_id_1 GLU _pdbx_validate_rmsd_angle.auth_seq_id_1 88 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CA _pdbx_validate_rmsd_angle.auth_asym_id_2 A _pdbx_validate_rmsd_angle.auth_comp_id_2 GLU _pdbx_validate_rmsd_angle.auth_seq_id_2 88 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 C _pdbx_validate_rmsd_angle.auth_asym_id_3 A _pdbx_validate_rmsd_angle.auth_comp_id_3 GLU _pdbx_validate_rmsd_angle.auth_seq_id_3 88 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 94.37 _pdbx_validate_rmsd_angle.angle_target_value 111.00 _pdbx_validate_rmsd_angle.angle_deviation -16.63 _pdbx_validate_rmsd_angle.angle_standard_deviation 2.70 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ALA A 37 ? ? -49.88 -71.60 2 1 ARG A 50 ? ? -57.28 -9.64 3 1 ARG A 76 ? ? -46.95 -15.12 4 1 TYR A 79 ? ? 31.91 58.00 5 1 PRO A 87 ? ? -58.72 -161.65 6 1 GLU A 88 ? ? -168.09 102.73 7 1 LEU A 99 ? ? -37.89 140.86 8 1 ARG A 100 ? ? 47.12 23.86 9 1 PRO A 102 ? ? -34.45 145.75 10 1 THR A 113 ? ? 165.92 147.24 11 1 PRO A 115 ? ? -66.21 67.96 12 1 ASN A 124 ? ? 59.83 74.53 13 1 LEU A 144 ? ? -104.73 -161.44 14 1 PRO A 155 ? ? -44.23 104.54 15 1 ASP A 181 ? ? 83.18 71.87 16 1 ASN B 33 ? ? 52.64 -81.08 17 1 GLN B 34 ? ? -145.88 13.22 18 1 GLU B 52 ? ? -49.87 -16.51 19 1 ARG B 55 ? ? -26.07 -64.26 20 1 VAL B 75 ? ? -46.64 -14.19 21 1 ASP B 76 ? ? -122.17 -57.89 22 1 TYR B 78 ? ? -107.05 -60.94 23 1 CYS B 79 ? ? -60.54 -81.49 24 1 THR B 90 ? ? -146.33 -69.81 25 1 ARG B 105 ? ? 47.88 109.63 26 1 GLN B 107 ? ? -36.79 -36.63 27 1 TYR B 123 ? ? -92.88 -86.36 28 1 PRO B 124 ? ? -32.17 114.99 29 1 SER B 135 ? ? 35.03 70.83 30 1 GLN B 136 ? ? -170.62 111.16 31 1 GLU B 138 ? ? -93.83 50.43 32 1 LYS B 139 ? ? -29.79 -15.32 33 1 PRO B 178 ? ? -55.37 46.78 34 1 GLU D 4 ? ? -131.36 -36.21 35 1 ALA D 37 ? ? -47.85 -75.65 36 1 ARG D 76 ? ? -58.19 9.73 37 1 ASN D 84 ? ? -58.73 109.63 38 1 PRO D 96 ? ? -45.78 168.49 39 1 LEU D 99 ? ? -33.35 132.12 40 1 ARG D 100 ? ? 73.13 -7.16 41 1 PRO D 102 ? ? -49.10 109.10 42 1 ASN D 103 ? ? -116.25 -167.17 43 1 THR D 113 ? ? 175.80 152.28 44 1 PRO D 115 ? ? -66.05 70.46 45 1 ASN D 124 ? ? 64.05 -20.56 46 1 THR D 130 ? ? -65.77 95.99 47 1 VAL D 136 ? ? -85.88 -125.47 48 1 HIS D 143 ? ? 80.52 33.49 49 1 LEU D 144 ? ? -105.27 -164.48 50 1 PRO D 155 ? ? -32.85 98.92 51 1 TRP D 168 ? ? -65.01 0.24 52 1 ASP D 171 ? ? -92.63 -61.81 53 1 PRO D 173 ? ? -30.28 148.89 54 1 THR E 3 ? ? -131.08 -75.02 55 1 ARG E 4 ? ? 13.85 100.81 56 1 PRO E 5 ? ? -40.22 102.10 57 1 ASN E 33 ? ? 51.69 -82.11 58 1 GLN E 34 ? ? -145.18 13.44 59 1 GLU E 52 ? ? -49.22 -18.96 60 1 ARG E 55 ? ? -24.34 -62.53 61 1 LYS E 65 ? ? -68.02 25.82 62 1 ASP E 66 ? ? -105.01 -61.80 63 1 CYS E 79 ? ? -60.52 -81.81 64 1 VAL E 85 ? ? -57.99 -5.51 65 1 GLU E 87 ? ? -62.90 0.05 66 1 THR E 90 ? ? -110.58 -82.64 67 1 VAL E 91 ? ? -54.05 0.67 68 1 GLN E 92 ? ? -140.65 -0.58 69 1 ARG E 94 ? ? -176.65 112.41 70 1 ARG E 105 ? ? 34.36 52.94 71 1 GLN E 110 ? ? 102.64 -3.35 72 1 HIS E 112 ? ? -11.72 154.86 73 1 LEU E 114 ? ? -170.84 103.94 74 1 TYR E 123 ? ? -119.00 -85.81 75 1 PRO E 124 ? ? -29.83 116.50 76 1 SER E 126 ? ? -38.00 135.97 77 1 SER E 135 ? ? 49.72 23.13 78 1 GLU E 137 ? ? -68.01 93.03 79 1 ASP E 152 ? ? -93.19 52.78 80 1 PRO E 165 ? ? -39.70 130.54 81 1 SER E 167 ? ? -3.75 121.67 82 1 PRO E 178 ? ? -67.15 2.40 # loop_ _pdbx_validate_chiral.id _pdbx_validate_chiral.PDB_model_num _pdbx_validate_chiral.auth_atom_id _pdbx_validate_chiral.label_alt_id _pdbx_validate_chiral.auth_asym_id _pdbx_validate_chiral.auth_comp_id _pdbx_validate_chiral.auth_seq_id _pdbx_validate_chiral.PDB_ins_code _pdbx_validate_chiral.details _pdbx_validate_chiral.omega 1 1 C1 ? A NAG 1184 ? 'WRONG HAND' . 2 1 C1 ? D NAG 1184 ? 'WRONG HAND' . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ILE 1 ? A ILE 1 2 1 Y 1 A LYS 2 ? A LYS 2 3 1 Y 1 B GLY 1 ? B GLY 1 4 1 Y 1 D ILE 1 ? D ILE 1 5 1 Y 1 D LYS 2 ? D LYS 2 6 1 Y 1 E GLY 1 ? E GLY 1 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 4 N-ACETYL-D-GLUCOSAMINE NAG 5 water HOH #