data_5IH7 # _entry.id 5IH7 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5IH7 WWPDB D_1000218728 # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5IH7 _pdbx_database_status.recvd_initial_deposition_date 2016-02-29 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site PDBE _pdbx_database_status.process_site PDBE _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal _audit_author.identifier_ORCID 'Pesaresi, A.' 1 ? 'Lamba, D.' 2 ? # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country ? _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'To Be Published' _citation.journal_id_ASTM ? _citation.journal_id_CSD 0353 _citation.journal_id_ISSN ? _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume ? _citation.language ? _citation.page_first ? _citation.page_last ? _citation.title 'Acetylcholinesterase of Torpedo californica in complex with the N-methyl-indoxylacetate hydrolysis products' _citation.year ? _citation.database_id_CSD ? _citation.pdbx_database_id_DOI ? _citation.pdbx_database_id_PubMed ? _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Pesaresi, A.' 1 primary 'Lamba, D.' 2 # _cell.entry_id 5IH7 _cell.length_a 111.990 _cell.length_b 111.990 _cell.length_c 137.050 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 6 _cell.pdbx_unique_axis ? # _symmetry.entry_id 5IH7 _symmetry.space_group_name_H-M 'P 31 2 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 152 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat Acetylcholinesterase 60447.211 1 3.1.1.7 ? ? ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 3 ? ? ? ? 3 non-polymer syn 1-methyl-1,2-dihydro-3H-indol-3-one 147.174 1 ? ? ? ? 4 non-polymer syn 'TETRAETHYLENE GLYCOL' 194.226 1 ? ? ? ? 5 non-polymer syn 'ACETATE ION' 59.044 1 ? ? ? ? 6 water nat water 18.015 303 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name AChE # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;DHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGS EMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGS QEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEG RRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILL GVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVI CPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGN PNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT ; _entity_poly.pdbx_seq_one_letter_code_can ;DHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGS EMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGS QEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEG RRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILL GVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVI CPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGN PNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ASP n 1 2 HIS n 1 3 SER n 1 4 GLU n 1 5 LEU n 1 6 LEU n 1 7 VAL n 1 8 ASN n 1 9 THR n 1 10 LYS n 1 11 SER n 1 12 GLY n 1 13 LYS n 1 14 VAL n 1 15 MET n 1 16 GLY n 1 17 THR n 1 18 ARG n 1 19 VAL n 1 20 PRO n 1 21 VAL n 1 22 LEU n 1 23 SER n 1 24 SER n 1 25 HIS n 1 26 ILE n 1 27 SER n 1 28 ALA n 1 29 PHE n 1 30 LEU n 1 31 GLY n 1 32 ILE n 1 33 PRO n 1 34 PHE n 1 35 ALA n 1 36 GLU n 1 37 PRO n 1 38 PRO n 1 39 VAL n 1 40 GLY n 1 41 ASN n 1 42 MET n 1 43 ARG n 1 44 PHE n 1 45 ARG n 1 46 ARG n 1 47 PRO n 1 48 GLU n 1 49 PRO n 1 50 LYS n 1 51 LYS n 1 52 PRO n 1 53 TRP n 1 54 SER n 1 55 GLY n 1 56 VAL n 1 57 TRP n 1 58 ASN n 1 59 ALA n 1 60 SER n 1 61 THR n 1 62 TYR n 1 63 PRO n 1 64 ASN n 1 65 ASN n 1 66 CYS n 1 67 GLN n 1 68 GLN n 1 69 TYR n 1 70 VAL n 1 71 ASP n 1 72 GLU n 1 73 GLN n 1 74 PHE n 1 75 PRO n 1 76 GLY n 1 77 PHE n 1 78 SER n 1 79 GLY n 1 80 SER n 1 81 GLU n 1 82 MET n 1 83 TRP n 1 84 ASN n 1 85 PRO n 1 86 ASN n 1 87 ARG n 1 88 GLU n 1 89 MET n 1 90 SER n 1 91 GLU n 1 92 ASP n 1 93 CYS n 1 94 LEU n 1 95 TYR n 1 96 LEU n 1 97 ASN n 1 98 ILE n 1 99 TRP n 1 100 VAL n 1 101 PRO n 1 102 SER n 1 103 PRO n 1 104 ARG n 1 105 PRO n 1 106 LYS n 1 107 SER n 1 108 THR n 1 109 THR n 1 110 VAL n 1 111 MET n 1 112 VAL n 1 113 TRP n 1 114 ILE n 1 115 TYR n 1 116 GLY n 1 117 GLY n 1 118 GLY n 1 119 PHE n 1 120 TYR n 1 121 SER n 1 122 GLY n 1 123 SER n 1 124 SER n 1 125 THR n 1 126 LEU n 1 127 ASP n 1 128 VAL n 1 129 TYR n 1 130 ASN n 1 131 GLY n 1 132 LYS n 1 133 TYR n 1 134 LEU n 1 135 ALA n 1 136 TYR n 1 137 THR n 1 138 GLU n 1 139 GLU n 1 140 VAL n 1 141 VAL n 1 142 LEU n 1 143 VAL n 1 144 SER n 1 145 LEU n 1 146 SER n 1 147 TYR n 1 148 ARG n 1 149 VAL n 1 150 GLY n 1 151 ALA n 1 152 PHE n 1 153 GLY n 1 154 PHE n 1 155 LEU n 1 156 ALA n 1 157 LEU n 1 158 HIS n 1 159 GLY n 1 160 SER n 1 161 GLN n 1 162 GLU n 1 163 ALA n 1 164 PRO n 1 165 GLY n 1 166 ASN n 1 167 VAL n 1 168 GLY n 1 169 LEU n 1 170 LEU n 1 171 ASP n 1 172 GLN n 1 173 ARG n 1 174 MET n 1 175 ALA n 1 176 LEU n 1 177 GLN n 1 178 TRP n 1 179 VAL n 1 180 HIS n 1 181 ASP n 1 182 ASN n 1 183 ILE n 1 184 GLN n 1 185 PHE n 1 186 PHE n 1 187 GLY n 1 188 GLY n 1 189 ASP n 1 190 PRO n 1 191 LYS n 1 192 THR n 1 193 VAL n 1 194 THR n 1 195 ILE n 1 196 PHE n 1 197 GLY n 1 198 GLU n 1 199 SER n 1 200 ALA n 1 201 GLY n 1 202 GLY n 1 203 ALA n 1 204 SER n 1 205 VAL n 1 206 GLY n 1 207 MET n 1 208 HIS n 1 209 ILE n 1 210 LEU n 1 211 SER n 1 212 PRO n 1 213 GLY n 1 214 SER n 1 215 ARG n 1 216 ASP n 1 217 LEU n 1 218 PHE n 1 219 ARG n 1 220 ARG n 1 221 ALA n 1 222 ILE n 1 223 LEU n 1 224 GLN n 1 225 SER n 1 226 GLY n 1 227 SER n 1 228 PRO n 1 229 ASN n 1 230 CYS n 1 231 PRO n 1 232 TRP n 1 233 ALA n 1 234 SER n 1 235 VAL n 1 236 SER n 1 237 VAL n 1 238 ALA n 1 239 GLU n 1 240 GLY n 1 241 ARG n 1 242 ARG n 1 243 ARG n 1 244 ALA n 1 245 VAL n 1 246 GLU n 1 247 LEU n 1 248 GLY n 1 249 ARG n 1 250 ASN n 1 251 LEU n 1 252 ASN n 1 253 CYS n 1 254 ASN n 1 255 LEU n 1 256 ASN n 1 257 SER n 1 258 ASP n 1 259 GLU n 1 260 GLU n 1 261 LEU n 1 262 ILE n 1 263 HIS n 1 264 CYS n 1 265 LEU n 1 266 ARG n 1 267 GLU n 1 268 LYS n 1 269 LYS n 1 270 PRO n 1 271 GLN n 1 272 GLU n 1 273 LEU n 1 274 ILE n 1 275 ASP n 1 276 VAL n 1 277 GLU n 1 278 TRP n 1 279 ASN n 1 280 VAL n 1 281 LEU n 1 282 PRO n 1 283 PHE n 1 284 ASP n 1 285 SER n 1 286 ILE n 1 287 PHE n 1 288 ARG n 1 289 PHE n 1 290 SER n 1 291 PHE n 1 292 VAL n 1 293 PRO n 1 294 VAL n 1 295 ILE n 1 296 ASP n 1 297 GLY n 1 298 GLU n 1 299 PHE n 1 300 PHE n 1 301 PRO n 1 302 THR n 1 303 SER n 1 304 LEU n 1 305 GLU n 1 306 SER n 1 307 MET n 1 308 LEU n 1 309 ASN n 1 310 SER n 1 311 GLY n 1 312 ASN n 1 313 PHE n 1 314 LYS n 1 315 LYS n 1 316 THR n 1 317 GLN n 1 318 ILE n 1 319 LEU n 1 320 LEU n 1 321 GLY n 1 322 VAL n 1 323 ASN n 1 324 LYS n 1 325 ASP n 1 326 GLU n 1 327 GLY n 1 328 SER n 1 329 PHE n 1 330 PHE n 1 331 LEU n 1 332 LEU n 1 333 TYR n 1 334 GLY n 1 335 ALA n 1 336 PRO n 1 337 GLY n 1 338 PHE n 1 339 SER n 1 340 LYS n 1 341 ASP n 1 342 SER n 1 343 GLU n 1 344 SER n 1 345 LYS n 1 346 ILE n 1 347 SER n 1 348 ARG n 1 349 GLU n 1 350 ASP n 1 351 PHE n 1 352 MET n 1 353 SER n 1 354 GLY n 1 355 VAL n 1 356 LYS n 1 357 LEU n 1 358 SER n 1 359 VAL n 1 360 PRO n 1 361 HIS n 1 362 ALA n 1 363 ASN n 1 364 ASP n 1 365 LEU n 1 366 GLY n 1 367 LEU n 1 368 ASP n 1 369 ALA n 1 370 VAL n 1 371 THR n 1 372 LEU n 1 373 GLN n 1 374 TYR n 1 375 THR n 1 376 ASP n 1 377 TRP n 1 378 MET n 1 379 ASP n 1 380 ASP n 1 381 ASN n 1 382 ASN n 1 383 GLY n 1 384 ILE n 1 385 LYS n 1 386 ASN n 1 387 ARG n 1 388 ASP n 1 389 GLY n 1 390 LEU n 1 391 ASP n 1 392 ASP n 1 393 ILE n 1 394 VAL n 1 395 GLY n 1 396 ASP n 1 397 HIS n 1 398 ASN n 1 399 VAL n 1 400 ILE n 1 401 CYS n 1 402 PRO n 1 403 LEU n 1 404 MET n 1 405 HIS n 1 406 PHE n 1 407 VAL n 1 408 ASN n 1 409 LYS n 1 410 TYR n 1 411 THR n 1 412 LYS n 1 413 PHE n 1 414 GLY n 1 415 ASN n 1 416 GLY n 1 417 THR n 1 418 TYR n 1 419 LEU n 1 420 TYR n 1 421 PHE n 1 422 PHE n 1 423 ASN n 1 424 HIS n 1 425 ARG n 1 426 ALA n 1 427 SER n 1 428 ASN n 1 429 LEU n 1 430 VAL n 1 431 TRP n 1 432 PRO n 1 433 GLU n 1 434 TRP n 1 435 MET n 1 436 GLY n 1 437 VAL n 1 438 ILE n 1 439 HIS n 1 440 GLY n 1 441 TYR n 1 442 GLU n 1 443 ILE n 1 444 GLU n 1 445 PHE n 1 446 VAL n 1 447 PHE n 1 448 GLY n 1 449 LEU n 1 450 PRO n 1 451 LEU n 1 452 VAL n 1 453 LYS n 1 454 GLU n 1 455 LEU n 1 456 ASN n 1 457 TYR n 1 458 THR n 1 459 ALA n 1 460 GLU n 1 461 GLU n 1 462 GLU n 1 463 ALA n 1 464 LEU n 1 465 SER n 1 466 ARG n 1 467 ARG n 1 468 ILE n 1 469 MET n 1 470 HIS n 1 471 TYR n 1 472 TRP n 1 473 ALA n 1 474 THR n 1 475 PHE n 1 476 ALA n 1 477 LYS n 1 478 THR n 1 479 GLY n 1 480 ASN n 1 481 PRO n 1 482 ASN n 1 483 GLU n 1 484 PRO n 1 485 HIS n 1 486 SER n 1 487 GLN n 1 488 GLU n 1 489 SER n 1 490 LYS n 1 491 TRP n 1 492 PRO n 1 493 LEU n 1 494 PHE n 1 495 THR n 1 496 THR n 1 497 LYS n 1 498 GLU n 1 499 GLN n 1 500 LYS n 1 501 PHE n 1 502 ILE n 1 503 ASP n 1 504 LEU n 1 505 ASN n 1 506 THR n 1 507 GLU n 1 508 PRO n 1 509 MET n 1 510 LYS n 1 511 VAL n 1 512 HIS n 1 513 GLN n 1 514 ARG n 1 515 LEU n 1 516 ARG n 1 517 VAL n 1 518 GLN n 1 519 MET n 1 520 CYS n 1 521 VAL n 1 522 PHE n 1 523 TRP n 1 524 ASN n 1 525 GLN n 1 526 PHE n 1 527 LEU n 1 528 PRO n 1 529 LYS n 1 530 LEU n 1 531 LEU n 1 532 ASN n 1 533 ALA n 1 534 THR n # _entity_src_nat.entity_id 1 _entity_src_nat.pdbx_src_id 1 _entity_src_nat.pdbx_alt_source_flag sample _entity_src_nat.pdbx_beg_seq_num 1 _entity_src_nat.pdbx_end_seq_num 534 _entity_src_nat.common_name 'Pacific electric ray' _entity_src_nat.pdbx_organism_scientific 'Tetronarce californica' _entity_src_nat.pdbx_ncbi_taxonomy_id 7787 _entity_src_nat.genus ? _entity_src_nat.species ? _entity_src_nat.strain ? _entity_src_nat.tissue ? _entity_src_nat.tissue_fraction ? _entity_src_nat.pdbx_secretion ? _entity_src_nat.pdbx_fragment ? _entity_src_nat.pdbx_variant ? _entity_src_nat.pdbx_cell_line ? _entity_src_nat.pdbx_atcc ? _entity_src_nat.pdbx_cellular_location ? _entity_src_nat.pdbx_organ ? _entity_src_nat.pdbx_organelle ? _entity_src_nat.pdbx_cell ? _entity_src_nat.pdbx_plasmid_name ? _entity_src_nat.pdbx_plasmid_details ? _entity_src_nat.details ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code ACES_TETCF _struct_ref.pdbx_db_accession P04058 _struct_ref.pdbx_db_isoform P04058-2 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGS EMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGS QEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEG RRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILL GVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVI CPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGN PNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT ; _struct_ref.pdbx_align_begin 23 # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 5IH7 _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 534 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession P04058 _struct_ref_seq.db_align_beg 23 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 556 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 2 _struct_ref_seq.pdbx_auth_seq_align_end 535 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ACT non-polymer . 'ACETATE ION' ? 'C2 H3 O2 -1' 59.044 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 OMI non-polymer . 1-methyl-1,2-dihydro-3H-indol-3-one ? 'C9 H9 N O' 147.174 PG4 non-polymer . 'TETRAETHYLENE GLYCOL' ? 'C8 H18 O5' 194.226 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5IH7 _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 4.07 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 69.79 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 277 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details 'MES 100mM, pH 6.2, PEG200 30%' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector PIXEL _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'DECTRIS PILATUS 2M' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2015-06-15 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'ELETTRA BEAMLINE 5.2R' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 5.2R _diffrn_source.pdbx_synchrotron_site ELETTRA # _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.entry_id 5IH7 _reflns.observed_criterion_sigma_I ? _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 35.410 _reflns.d_resolution_high 2.4 _reflns.number_obs 44595 _reflns.number_all 39320 _reflns.percent_possible_obs 99.8 _reflns.pdbx_Rmerge_I_obs 0.078 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 12.9 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 4.500 _reflns.pdbx_CC_half ? # _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_ordinal 1 _reflns_shell.d_res_high 2.40 _reflns_shell.d_res_low 2.53 _reflns_shell.percent_possible_all 99.7 _reflns_shell.Rmerge_I_obs 0.2730 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 4.9 _reflns_shell.pdbx_redundancy 4.30 _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_all ? _reflns_shell.pdbx_CC_half ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 5IH7 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 37298 _refine.ls_number_reflns_all 39380 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 35.41 _refine.ls_d_res_high 2.40 _refine.ls_percent_reflns_obs 99.7 _refine.ls_R_factor_obs 0.172 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.170 _refine.ls_R_factor_R_free 0.207 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.000 _refine.ls_number_reflns_R_free 1978 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.957 _refine.correlation_coeff_Fo_to_Fc_free 0.936 _refine.B_iso_mean 37.16 _refine.aniso_B[1][1] 1.12000 _refine.aniso_B[2][2] 1.12000 _refine.aniso_B[3][3] -3.63000 _refine.aniso_B[1][2] 1.12000 _refine.aniso_B[1][3] 0.00000 _refine.aniso_B[2][3] 0.00000 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ;HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS ; _refine.pdbx_starting_model 1EA5 _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.206 _refine.pdbx_overall_ESU_R_Free 0.178 _refine.overall_SU_ML 0.112 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 4.769 _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 4263 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 69 _refine_hist.number_atoms_solvent 303 _refine_hist.number_atoms_total 4635 _refine_hist.d_res_high 2.40 _refine_hist.d_res_low 35.41 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.020 0.019 ? 4452 'X-RAY DIFFRACTION' ? r_bond_other_d 0.002 0.020 ? 4106 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.947 1.958 ? 6045 'X-RAY DIFFRACTION' ? r_angle_other_deg 0.946 3.004 ? 9431 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.561 5.000 ? 533 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 33.232 24.028 ? 211 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 16.786 15.000 ? 706 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 21.613 15.000 ? 24 'X-RAY DIFFRACTION' ? r_chiral_restr 0.129 0.200 ? 636 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.010 0.021 ? 5054 'X-RAY DIFFRACTION' ? r_gen_planes_other 0.001 0.020 ? 1078 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 3.147 3.412 ? 2135 'X-RAY DIFFRACTION' ? r_mcbond_other 3.128 3.409 ? 2134 'X-RAY DIFFRACTION' ? r_mcangle_it 4.387 5.102 ? 2667 'X-RAY DIFFRACTION' ? r_mcangle_other 4.390 5.105 ? 2668 'X-RAY DIFFRACTION' ? r_scbond_it 4.464 3.915 ? 2317 'X-RAY DIFFRACTION' ? r_scbond_other 4.463 3.916 ? 2318 'X-RAY DIFFRACTION' ? r_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_other 6.615 5.697 ? 3379 'X-RAY DIFFRACTION' ? r_long_range_B_refined 7.982 28.334 ? 5396 'X-RAY DIFFRACTION' ? r_long_range_B_other 7.976 28.159 ? 5287 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.40 _refine_ls_shell.d_res_low 2.53 _refine_ls_shell.number_reflns_R_work 2713 _refine_ls_shell.R_factor_R_work 0.2230 _refine_ls_shell.percent_reflns_obs 99.79 _refine_ls_shell.R_factor_R_free 0.2820 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 135 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_obs ? _refine_ls_shell.number_reflns_obs ? # _struct.entry_id 5IH7 _struct.title 'Acetylcholinesterase of Torpedo californica in complex with the N-methyl-indoxylacetate hydrolysis products' _struct.pdbx_descriptor 'Acetylcholinesterase (E.C.3.1.1.7)' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5IH7 _struct_keywords.text 'Acetylcholinesterase NMIA, hydrolase' _struct_keywords.pdbx_keywords HYDROLASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 2 ? E N N 3 ? F N N 4 ? G N N 5 ? H N N 6 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 VAL A 39 ? ARG A 43 ? VAL A 40 ARG A 44 5 ? 5 HELX_P HELX_P2 AA2 PHE A 77 ? MET A 82 ? PHE A 78 MET A 83 1 ? 6 HELX_P HELX_P3 AA3 LEU A 126 ? ASN A 130 ? LEU A 127 ASN A 131 5 ? 5 HELX_P HELX_P4 AA4 GLY A 131 ? GLU A 139 ? GLY A 132 GLU A 140 1 ? 9 HELX_P HELX_P5 AA5 VAL A 149 ? LEU A 155 ? VAL A 150 LEU A 156 1 ? 7 HELX_P HELX_P6 AA6 ASN A 166 ? ILE A 183 ? ASN A 167 ILE A 184 1 ? 18 HELX_P HELX_P7 AA7 GLN A 184 ? PHE A 186 ? GLN A 185 PHE A 187 5 ? 3 HELX_P HELX_P8 AA8 SER A 199 ? SER A 211 ? SER A 200 SER A 212 1 ? 13 HELX_P HELX_P9 AA9 SER A 214 ? PHE A 218 ? SER A 215 PHE A 219 5 ? 5 HELX_P HELX_P10 AB1 VAL A 237 ? LEU A 251 ? VAL A 238 LEU A 252 1 ? 15 HELX_P HELX_P11 AB2 SER A 257 ? LYS A 268 ? SER A 258 LYS A 269 1 ? 12 HELX_P HELX_P12 AB3 LYS A 269 ? GLU A 277 ? LYS A 270 GLU A 278 1 ? 9 HELX_P HELX_P13 AB4 TRP A 278 ? LEU A 281 ? TRP A 279 LEU A 282 5 ? 4 HELX_P HELX_P14 AB5 SER A 303 ? GLY A 311 ? SER A 304 GLY A 312 1 ? 9 HELX_P HELX_P15 AB6 GLY A 327 ? ALA A 335 ? GLY A 328 ALA A 336 1 ? 9 HELX_P HELX_P16 AB7 SER A 347 ? VAL A 359 ? SER A 348 VAL A 360 1 ? 13 HELX_P HELX_P17 AB8 ASN A 363 ? THR A 375 ? ASN A 364 THR A 376 1 ? 13 HELX_P HELX_P18 AB9 ASN A 382 ? VAL A 399 ? ASN A 383 VAL A 400 1 ? 18 HELX_P HELX_P19 AC1 VAL A 399 ? LYS A 412 ? VAL A 400 LYS A 413 1 ? 14 HELX_P HELX_P20 AC2 PRO A 432 ? GLY A 436 ? PRO A 433 GLY A 437 5 ? 5 HELX_P HELX_P21 AC3 GLU A 442 ? PHE A 447 ? GLU A 443 PHE A 448 1 ? 6 HELX_P HELX_P22 AC4 GLY A 448 ? ASN A 456 ? GLY A 449 ASN A 457 5 ? 9 HELX_P HELX_P23 AC5 THR A 458 ? GLY A 479 ? THR A 459 GLY A 480 1 ? 22 HELX_P HELX_P24 AC6 ARG A 516 ? GLN A 525 ? ARG A 517 GLN A 526 1 ? 10 HELX_P HELX_P25 AC7 GLN A 525 ? THR A 534 ? GLN A 526 THR A 535 1 ? 10 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 66 SG ? ? ? 1_555 A CYS 93 SG ? ? A CYS 67 A CYS 94 1_555 ? ? ? ? ? ? ? 2.051 ? disulf2 disulf ? ? A CYS 253 SG ? ? ? 1_555 A CYS 264 SG ? ? A CYS 254 A CYS 265 1_555 ? ? ? ? ? ? ? 2.020 ? disulf3 disulf ? ? A CYS 401 SG ? ? ? 1_555 A CYS 520 SG ? ? A CYS 402 A CYS 521 1_555 ? ? ? ? ? ? ? 2.054 ? covale1 covale one ? A ASN 58 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 59 A NAG 601 1_555 ? ? ? ? ? ? ? 1.316 ? covale2 covale one ? A ASN 415 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 416 A NAG 602 1_555 ? ? ? ? ? ? ? 1.471 ? covale3 covale both ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 602 A NAG 603 1_555 ? ? ? ? ? ? ? 1.439 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # _struct_mon_prot_cis.pdbx_id 1 _struct_mon_prot_cis.label_comp_id SER _struct_mon_prot_cis.label_seq_id 102 _struct_mon_prot_cis.label_asym_id A _struct_mon_prot_cis.label_alt_id . _struct_mon_prot_cis.pdbx_PDB_ins_code ? _struct_mon_prot_cis.auth_comp_id SER _struct_mon_prot_cis.auth_seq_id 103 _struct_mon_prot_cis.auth_asym_id A _struct_mon_prot_cis.pdbx_label_comp_id_2 PRO _struct_mon_prot_cis.pdbx_label_seq_id_2 103 _struct_mon_prot_cis.pdbx_label_asym_id_2 A _struct_mon_prot_cis.pdbx_PDB_ins_code_2 ? _struct_mon_prot_cis.pdbx_auth_comp_id_2 PRO _struct_mon_prot_cis.pdbx_auth_seq_id_2 104 _struct_mon_prot_cis.pdbx_auth_asym_id_2 A _struct_mon_prot_cis.pdbx_PDB_model_num 1 _struct_mon_prot_cis.pdbx_omega_angle 5.17 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 3 ? AA2 ? 11 ? AA3 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? parallel AA2 1 2 ? anti-parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA2 4 5 ? parallel AA2 5 6 ? parallel AA2 6 7 ? parallel AA2 7 8 ? parallel AA2 8 9 ? parallel AA2 9 10 ? parallel AA2 10 11 ? anti-parallel AA3 1 2 ? parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 LEU A 6 ? THR A 9 ? LEU A 7 THR A 10 AA1 2 GLY A 12 ? MET A 15 ? GLY A 13 MET A 16 AA1 3 VAL A 56 ? ASN A 58 ? VAL A 57 ASN A 59 AA2 1 THR A 17 ? PRO A 20 ? THR A 18 PRO A 21 AA2 2 HIS A 25 ? PRO A 33 ? HIS A 26 PRO A 34 AA2 3 TYR A 95 ? VAL A 100 ? TYR A 96 VAL A 101 AA2 4 VAL A 141 ? SER A 144 ? VAL A 142 SER A 145 AA2 5 THR A 108 ? ILE A 114 ? THR A 109 ILE A 115 AA2 6 GLY A 188 ? GLU A 198 ? GLY A 189 GLU A 199 AA2 7 ARG A 220 ? GLN A 224 ? ARG A 221 GLN A 225 AA2 8 ILE A 318 ? ASN A 323 ? ILE A 319 ASN A 324 AA2 9 THR A 417 ? PHE A 422 ? THR A 418 PHE A 423 AA2 10 LYS A 500 ? LEU A 504 ? LYS A 501 LEU A 505 AA2 11 VAL A 511 ? GLN A 513 ? VAL A 512 GLN A 514 AA3 1 VAL A 235 ? SER A 236 ? VAL A 236 SER A 237 AA3 2 VAL A 294 ? ILE A 295 ? VAL A 295 ILE A 296 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N VAL A 7 ? N VAL A 8 O VAL A 14 ? O VAL A 15 AA1 2 3 N MET A 15 ? N MET A 16 O TRP A 57 ? O TRP A 58 AA2 1 2 N VAL A 19 ? N VAL A 20 O ILE A 26 ? O ILE A 27 AA2 2 3 N SER A 27 ? N SER A 28 O VAL A 100 ? O VAL A 101 AA2 3 4 N ASN A 97 ? N ASN A 98 O SER A 144 ? O SER A 145 AA2 4 5 O VAL A 143 ? O VAL A 144 N MET A 111 ? N MET A 112 AA2 5 6 N THR A 108 ? N THR A 109 O ASP A 189 ? O ASP A 190 AA2 6 7 N ILE A 195 ? N ILE A 196 O ILE A 222 ? O ILE A 223 AA2 7 8 N LEU A 223 ? N LEU A 224 O LEU A 319 ? O LEU A 320 AA2 8 9 N VAL A 322 ? N VAL A 323 O PHE A 422 ? O PHE A 423 AA2 9 10 N PHE A 421 ? N PHE A 422 O LEU A 504 ? O LEU A 505 AA2 10 11 N PHE A 501 ? N PHE A 502 O HIS A 512 ? O HIS A 513 AA3 1 2 N VAL A 235 ? N VAL A 236 O ILE A 295 ? O ILE A 296 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A OMI 604 ? 8 'binding site for residue OMI A 604' AC2 Software A PG4 605 ? 5 'binding site for residue PG4 A 605' AC3 Software A ACT 606 ? 6 'binding site for residue ACT A 606' AC4 Software A NAG 601 ? 3 'binding site for Mono-Saccharide NAG A 601 bound to ASN A 59' AC5 Software A ASN 416 ? 1 'binding site for Poly-Saccharide residues NAG A 602 through NAG A 603 bound to ASN A 416' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 8 TRP A 83 ? TRP A 84 . ? 1_555 ? 2 AC1 8 GLY A 116 ? GLY A 117 . ? 1_555 ? 3 AC1 8 GLY A 117 ? GLY A 118 . ? 1_555 ? 4 AC1 8 GLU A 198 ? GLU A 199 . ? 1_555 ? 5 AC1 8 HIS A 439 ? HIS A 440 . ? 1_555 ? 6 AC1 8 PG4 F . ? PG4 A 605 . ? 1_555 ? 7 AC1 8 ACT G . ? ACT A 606 . ? 1_555 ? 8 AC1 8 HOH H . ? HOH A 816 . ? 1_555 ? 9 AC2 5 TYR A 69 ? TYR A 70 . ? 1_555 ? 10 AC2 5 TYR A 120 ? TYR A 121 . ? 1_555 ? 11 AC2 5 TRP A 278 ? TRP A 279 . ? 1_555 ? 12 AC2 5 PHE A 329 ? PHE A 330 . ? 1_555 ? 13 AC2 5 OMI E . ? OMI A 604 . ? 1_555 ? 14 AC3 6 GLY A 117 ? GLY A 118 . ? 1_555 ? 15 AC3 6 GLY A 118 ? GLY A 119 . ? 1_555 ? 16 AC3 6 SER A 199 ? SER A 200 . ? 1_555 ? 17 AC3 6 ALA A 200 ? ALA A 201 . ? 1_555 ? 18 AC3 6 HIS A 439 ? HIS A 440 . ? 1_555 ? 19 AC3 6 OMI E . ? OMI A 604 . ? 1_555 ? 20 AC4 3 ASN A 58 ? ASN A 59 . ? 1_555 ? 21 AC4 3 SER A 60 ? SER A 61 . ? 1_555 ? 22 AC4 3 THR A 61 ? THR A 62 . ? 1_555 ? 23 AC5 1 ASN A 415 ? ASN A 416 . ? 1_555 ? # _atom_sites.entry_id 5IH7 _atom_sites.fract_transf_matrix[1][1] 0.008929 _atom_sites.fract_transf_matrix[1][2] 0.005155 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.010311 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007297 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASP A 1 1 ? -71.157 12.877 -6.300 0.50 47.71 ? 2 ASP A N 1 ATOM 2 C CA . ASP A 1 1 ? -70.329 12.573 -7.495 0.50 50.38 ? 2 ASP A CA 1 ATOM 3 C C . ASP A 1 1 ? -70.608 11.132 -7.792 0.50 55.57 ? 2 ASP A C 1 ATOM 4 O O . ASP A 1 1 ? -70.815 10.354 -6.861 0.50 56.01 ? 2 ASP A O 1 ATOM 5 C CB . ASP A 1 1 ? -68.835 12.778 -7.234 0.50 49.70 ? 2 ASP A CB 1 ATOM 6 C CG . ASP A 1 1 ? -67.636 13.529 -7.013 0.10 43.54 ? 2 ASP A CG 1 ATOM 7 O OD1 . ASP A 1 1 ? -67.758 14.346 -7.949 0.10 42.36 ? 2 ASP A OD1 1 ATOM 8 O OD2 . ASP A 1 1 ? -67.007 13.786 -5.965 0.10 42.36 ? 2 ASP A OD2 1 ATOM 9 N N . HIS A 1 2 ? -70.660 10.796 -9.082 0.50 56.64 ? 3 HIS A N 1 ATOM 10 C CA . HIS A 1 2 ? -70.993 9.455 -9.514 0.50 55.18 ? 3 HIS A CA 1 ATOM 11 C C . HIS A 1 2 ? -69.847 8.731 -10.287 0.50 57.45 ? 3 HIS A C 1 ATOM 12 O O . HIS A 1 2 ? -69.573 7.579 -9.974 0.50 59.86 ? 3 HIS A O 1 ATOM 13 C CB . HIS A 1 2 ? -72.315 9.485 -10.293 0.50 51.02 ? 3 HIS A CB 1 ATOM 14 C CG . HIS A 1 2 ? -73.396 9.713 -9.809 0.10 41.92 ? 3 HIS A CG 1 ATOM 15 N ND1 . HIS A 1 2 ? -74.042 8.605 -9.299 0.10 40.71 ? 3 HIS A ND1 1 ATOM 16 C CD2 . HIS A 1 2 ? -74.209 10.767 -9.560 0.10 40.71 ? 3 HIS A CD2 1 ATOM 17 C CE1 . HIS A 1 2 ? -75.184 8.978 -8.749 0.10 40.25 ? 3 HIS A CE1 1 ATOM 18 N NE2 . HIS A 1 2 ? -75.307 10.285 -8.894 0.10 40.25 ? 3 HIS A NE2 1 ATOM 19 N N . SER A 1 3 ? -69.165 9.389 -11.246 1.00 63.85 ? 4 SER A N 1 ATOM 20 C CA . SER A 1 3 ? -68.120 8.728 -12.129 1.00 57.10 ? 4 SER A CA 1 ATOM 21 C C . SER A 1 3 ? -67.079 9.650 -12.821 1.00 51.08 ? 4 SER A C 1 ATOM 22 O O . SER A 1 3 ? -67.274 10.860 -12.903 1.00 46.19 ? 4 SER A O 1 ATOM 23 C CB . SER A 1 3 ? -68.802 7.941 -13.264 1.00 57.47 ? 4 SER A CB 1 ATOM 24 O OG . SER A 1 3 ? -69.054 8.780 -14.395 1.00 54.81 ? 4 SER A OG 1 ATOM 25 N N . GLU A 1 4 ? -66.043 9.041 -13.416 1.00 45.36 ? 5 GLU A N 1 ATOM 26 C CA . GLU A 1 4 ? -64.864 9.750 -13.967 1.00 43.68 ? 5 GLU A CA 1 ATOM 27 C C . GLU A 1 4 ? -65.097 10.807 -15.061 1.00 41.42 ? 5 GLU A C 1 ATOM 28 O O . GLU A 1 4 ? -64.282 11.689 -15.247 1.00 41.34 ? 5 GLU A O 1 ATOM 29 C CB . GLU A 1 4 ? -63.909 8.737 -14.564 1.00 45.63 ? 5 GLU A CB 1 ATOM 30 C CG . GLU A 1 4 ? -62.568 9.333 -15.007 1.00 47.97 ? 5 GLU A CG 1 ATOM 31 C CD . GLU A 1 4 ? -61.484 8.289 -15.075 1.00 45.87 ? 5 GLU A CD 1 ATOM 32 O OE1 . GLU A 1 4 ? -61.853 7.118 -15.094 1.00 51.69 ? 5 GLU A OE1 1 ATOM 33 O OE2 . GLU A 1 4 ? -60.283 8.616 -15.054 1.00 49.31 ? 5 GLU A OE2 1 ATOM 34 N N . LEU A 1 5 ? -66.187 10.650 -15.779 1.00 39.47 ? 6 LEU A N 1 ATOM 35 C CA . LEU A 1 5 ? -66.577 11.398 -16.924 1.00 40.70 ? 6 LEU A CA 1 ATOM 36 C C . LEU A 1 5 ? -67.642 12.416 -16.551 1.00 38.06 ? 6 LEU A C 1 ATOM 37 O O . LEU A 1 5 ? -68.127 13.194 -17.393 1.00 39.56 ? 6 LEU A O 1 ATOM 38 C CB . LEU A 1 5 ? -67.159 10.436 -17.990 1.00 37.24 ? 6 LEU A CB 1 ATOM 39 C CG . LEU A 1 5 ? -66.217 9.411 -18.640 1.00 40.96 ? 6 LEU A CG 1 ATOM 40 C CD1 . LEU A 1 5 ? -67.005 8.514 -19.666 1.00 40.77 ? 6 LEU A CD1 1 ATOM 41 C CD2 . LEU A 1 5 ? -65.018 10.063 -19.318 1.00 41.79 ? 6 LEU A CD2 1 ATOM 42 N N . LEU A 1 6 ? -68.038 12.423 -15.304 1.00 37.30 ? 7 LEU A N 1 ATOM 43 C CA . LEU A 1 6 ? -68.984 13.432 -14.861 1.00 40.38 ? 7 LEU A CA 1 ATOM 44 C C . LEU A 1 6 ? -68.236 14.457 -13.983 1.00 39.48 ? 7 LEU A C 1 ATOM 45 O O . LEU A 1 6 ? -67.493 14.101 -13.040 1.00 37.17 ? 7 LEU A O 1 ATOM 46 C CB . LEU A 1 6 ? -70.132 12.766 -14.137 1.00 48.36 ? 7 LEU A CB 1 ATOM 47 C CG . LEU A 1 6 ? -71.273 13.667 -13.639 1.00 57.88 ? 7 LEU A CG 1 ATOM 48 C CD1 . LEU A 1 6 ? -71.941 14.413 -14.787 1.00 63.46 ? 7 LEU A CD1 1 ATOM 49 C CD2 . LEU A 1 6 ? -72.308 12.815 -12.890 1.00 61.44 ? 7 LEU A CD2 1 ATOM 50 N N . VAL A 1 7 ? -68.327 15.733 -14.353 1.00 39.98 ? 8 VAL A N 1 ATOM 51 C CA . VAL A 1 7 ? -67.655 16.782 -13.557 1.00 35.03 ? 8 VAL A CA 1 ATOM 52 C C . VAL A 1 7 ? -68.693 17.823 -13.294 1.00 33.75 ? 8 VAL A C 1 ATOM 53 O O . VAL A 1 7 ? -69.483 18.169 -14.158 1.00 37.14 ? 8 VAL A O 1 ATOM 54 C CB . VAL A 1 7 ? -66.432 17.344 -14.267 1.00 35.48 ? 8 VAL A CB 1 ATOM 55 C CG1 . VAL A 1 7 ? -65.869 18.569 -13.545 1.00 35.22 ? 8 VAL A CG1 1 ATOM 56 C CG2 . VAL A 1 7 ? -65.384 16.264 -14.433 1.00 35.33 ? 8 VAL A CG2 1 ATOM 57 N N . ASN A 1 8 ? -68.754 18.252 -12.049 1.00 38.55 ? 9 ASN A N 1 ATOM 58 C CA . ASN A 1 8 ? -69.683 19.305 -11.664 1.00 38.96 ? 9 ASN A CA 1 ATOM 59 C C . ASN A 1 8 ? -68.874 20.586 -11.604 1.00 33.70 ? 9 ASN A C 1 ATOM 60 O O . ASN A 1 8 ? -67.812 20.596 -11.017 1.00 38.91 ? 9 ASN A O 1 ATOM 61 C CB . ASN A 1 8 ? -70.371 18.982 -10.330 1.00 43.25 ? 9 ASN A CB 1 ATOM 62 C CG . ASN A 1 8 ? -71.442 19.997 -9.987 1.00 54.90 ? 9 ASN A CG 1 ATOM 63 O OD1 . ASN A 1 8 ? -72.083 20.617 -10.875 1.00 53.19 ? 9 ASN A OD1 1 ATOM 64 N ND2 . ASN A 1 8 ? -71.619 20.219 -8.696 1.00 62.83 ? 9 ASN A ND2 1 ATOM 65 N N . THR A 1 9 ? -69.329 21.618 -12.310 1.00 31.12 ? 10 THR A N 1 ATOM 66 C CA . THR A 1 9 ? -68.647 22.860 -12.371 1.00 35.38 ? 10 THR A CA 1 ATOM 67 C C . THR A 1 9 ? -69.602 23.893 -11.856 1.00 33.31 ? 10 THR A C 1 ATOM 68 O O . THR A 1 9 ? -70.769 23.623 -11.752 1.00 31.47 ? 10 THR A O 1 ATOM 69 C CB . THR A 1 9 ? -68.211 23.262 -13.845 1.00 33.19 ? 10 THR A CB 1 ATOM 70 O OG1 . THR A 1 9 ? -69.317 23.774 -14.576 1.00 29.38 ? 10 THR A OG1 1 ATOM 71 C CG2 . THR A 1 9 ? -67.602 22.131 -14.582 1.00 34.20 ? 10 THR A CG2 1 ATOM 72 N N . LYS A 1 10 ? -69.099 25.115 -11.710 1.00 35.84 ? 11 LYS A N 1 ATOM 73 C CA . LYS A 1 10 ? -69.899 26.296 -11.331 1.00 34.39 ? 11 LYS A CA 1 ATOM 74 C C . LYS A 1 10 ? -70.911 26.661 -12.387 1.00 35.70 ? 11 LYS A C 1 ATOM 75 O O . LYS A 1 10 ? -71.851 27.414 -12.141 1.00 37.57 ? 11 LYS A O 1 ATOM 76 C CB . LYS A 1 10 ? -68.922 27.472 -11.077 1.00 35.05 ? 11 LYS A CB 1 ATOM 77 C CG . LYS A 1 10 ? -67.843 27.116 -9.994 1.00 34.05 ? 11 LYS A CG 1 ATOM 78 C CD . LYS A 1 10 ? -66.838 28.258 -9.715 1.00 34.29 ? 11 LYS A CD 1 ATOM 79 C CE . LYS A 1 10 ? -65.850 27.912 -8.596 1.00 33.60 ? 11 LYS A CE 1 ATOM 80 N NZ . LYS A 1 10 ? -64.738 28.909 -8.529 1.00 39.49 ? 11 LYS A NZ 1 ATOM 81 N N . SER A 1 11 ? -70.747 26.134 -13.595 1.00 37.89 ? 12 SER A N 1 ATOM 82 C CA . SER A 1 11 ? -71.706 26.464 -14.654 1.00 38.91 ? 12 SER A CA 1 ATOM 83 C C . SER A 1 11 ? -72.754 25.357 -14.771 1.00 36.17 ? 12 SER A C 1 ATOM 84 O O . SER A 1 11 ? -73.848 25.545 -15.385 1.00 35.16 ? 12 SER A O 1 ATOM 85 C CB . SER A 1 11 ? -70.954 26.731 -15.974 1.00 44.83 ? 12 SER A CB 1 ATOM 86 O OG . SER A 1 11 ? -70.065 27.839 -15.820 1.00 44.07 ? 12 SER A OG 1 ATOM 87 N N . GLY A 1 12 ? -72.440 24.223 -14.141 1.00 35.52 ? 13 GLY A N 1 ATOM 88 C CA . GLY A 1 12 ? -73.305 23.058 -14.163 1.00 34.47 ? 13 GLY A CA 1 ATOM 89 C C . GLY A 1 12 ? -72.513 21.801 -14.380 1.00 35.63 ? 13 GLY A C 1 ATOM 90 O O . GLY A 1 12 ? -71.267 21.840 -14.408 1.00 38.12 ? 13 GLY A O 1 ATOM 91 N N . LYS A 1 13 ? -73.230 20.681 -14.510 1.00 37.81 ? 14 LYS A N 1 ATOM 92 C CA . LYS A 1 13 ? -72.593 19.389 -14.675 1.00 41.77 ? 14 LYS A CA 1 ATOM 93 C C . LYS A 1 13 ? -72.245 19.161 -16.137 1.00 39.53 ? 14 LYS A C 1 ATOM 94 O O . LYS A 1 13 ? -72.910 19.646 -17.046 1.00 36.83 ? 14 LYS A O 1 ATOM 95 C CB . LYS A 1 13 ? -73.506 18.280 -14.173 1.00 47.03 ? 14 LYS A CB 1 ATOM 96 C CG . LYS A 1 13 ? -73.198 17.848 -12.727 1.00 57.79 ? 14 LYS A CG 1 ATOM 97 C CD . LYS A 1 13 ? -74.269 16.974 -12.050 1.00 59.22 ? 14 LYS A CD 1 ATOM 98 C CE . LYS A 1 13 ? -75.604 17.733 -11.975 1.00 66.66 ? 14 LYS A CE 1 ATOM 99 N NZ . LYS A 1 13 ? -76.452 17.439 -10.771 1.00 66.07 ? 14 LYS A NZ 1 ATOM 100 N N . VAL A 1 14 ? -71.247 18.355 -16.364 1.00 34.39 ? 15 VAL A N 1 ATOM 101 C CA . VAL A 1 14 ? -70.760 18.157 -17.690 1.00 38.02 ? 15 VAL A CA 1 ATOM 102 C C . VAL A 1 14 ? -70.432 16.698 -17.851 1.00 35.21 ? 15 VAL A C 1 ATOM 103 O O . VAL A 1 14 ? -69.840 16.113 -16.941 1.00 31.32 ? 15 VAL A O 1 ATOM 104 C CB . VAL A 1 14 ? -69.491 19.054 -17.810 1.00 42.20 ? 15 VAL A CB 1 ATOM 105 C CG1 . VAL A 1 14 ? -68.273 18.311 -18.272 1.00 47.82 ? 15 VAL A CG1 1 ATOM 106 C CG2 . VAL A 1 14 ? -69.782 20.274 -18.612 1.00 41.24 ? 15 VAL A CG2 1 ATOM 107 N N . MET A 1 15 ? -70.805 16.097 -18.984 1.00 35.32 ? 16 MET A N 1 ATOM 108 C CA . MET A 1 15 ? -70.472 14.674 -19.230 1.00 36.56 ? 16 MET A CA 1 ATOM 109 C C . MET A 1 15 ? -69.475 14.472 -20.364 1.00 34.61 ? 16 MET A C 1 ATOM 110 O O . MET A 1 15 ? -69.698 14.856 -21.524 1.00 35.59 ? 16 MET A O 1 ATOM 111 C CB . MET A 1 15 ? -71.743 13.839 -19.461 1.00 43.94 ? 16 MET A CB 1 ATOM 112 C CG . MET A 1 15 ? -71.521 12.334 -19.779 1.00 50.74 ? 16 MET A CG 1 ATOM 113 S SD . MET A 1 15 ? -70.963 11.296 -18.398 1.00 62.21 ? 16 MET A SD 1 ATOM 114 C CE . MET A 1 15 ? -72.602 11.071 -17.652 1.00 67.54 ? 16 MET A CE 1 ATOM 115 N N . GLY A 1 16 ? -68.362 13.859 -20.033 1.00 32.89 ? 17 GLY A N 1 ATOM 116 C CA . GLY A 1 16 ? -67.330 13.655 -21.023 1.00 37.59 ? 17 GLY A CA 1 ATOM 117 C C . GLY A 1 16 ? -67.496 12.362 -21.788 1.00 38.37 ? 17 GLY A C 1 ATOM 118 O O . GLY A 1 16 ? -68.552 11.759 -21.749 1.00 41.08 ? 17 GLY A O 1 ATOM 119 N N . THR A 1 17 ? -66.409 11.941 -22.436 1.00 39.95 ? 18 THR A N 1 ATOM 120 C CA . THR A 1 17 ? -66.342 10.730 -23.218 1.00 36.64 ? 18 THR A CA 1 ATOM 121 C C . THR A 1 17 ? -64.972 10.206 -23.065 1.00 35.67 ? 18 THR A C 1 ATOM 122 O O . THR A 1 17 ? -64.069 10.988 -22.901 1.00 38.49 ? 18 THR A O 1 ATOM 123 C CB . THR A 1 17 ? -66.595 10.957 -24.707 1.00 38.86 ? 18 THR A CB 1 ATOM 124 O OG1 . THR A 1 17 ? -66.567 9.689 -25.335 1.00 39.19 ? 18 THR A OG1 1 ATOM 125 C CG2 . THR A 1 17 ? -65.487 11.807 -25.399 1.00 39.78 ? 18 THR A CG2 1 ATOM 126 N N . ARG A 1 18 ? -64.838 8.887 -23.010 1.00 36.83 ? 19 ARG A N 1 ATOM 127 C CA . ARG A 1 18 ? -63.536 8.199 -22.833 1.00 39.85 ? 19 ARG A CA 1 ATOM 128 C C . ARG A 1 18 ? -62.957 8.014 -24.235 1.00 43.84 ? 19 ARG A C 1 ATOM 129 O O . ARG A 1 18 ? -63.694 7.734 -25.182 1.00 43.54 ? 19 ARG A O 1 ATOM 130 C CB . ARG A 1 18 ? -63.743 6.840 -22.183 1.00 38.35 ? 19 ARG A CB 1 ATOM 131 C CG . ARG A 1 18 ? -62.487 6.092 -21.848 1.00 43.76 ? 19 ARG A CG 1 ATOM 132 C CD . ARG A 1 18 ? -62.672 5.231 -20.559 1.00 48.57 ? 19 ARG A CD 1 ATOM 133 N NE . ARG A 1 18 ? -61.503 4.344 -20.287 1.00 52.80 ? 19 ARG A NE 1 ATOM 134 C CZ . ARG A 1 18 ? -60.407 4.646 -19.571 1.00 56.73 ? 19 ARG A CZ 1 ATOM 135 N NH1 . ARG A 1 18 ? -60.240 5.847 -19.006 1.00 65.55 ? 19 ARG A NH1 1 ATOM 136 N NH2 . ARG A 1 18 ? -59.434 3.743 -19.448 1.00 55.19 ? 19 ARG A NH2 1 ATOM 137 N N . VAL A 1 19 ? -61.659 8.217 -24.388 1.00 41.36 ? 20 VAL A N 1 ATOM 138 C CA . VAL A 1 19 ? -61.105 8.366 -25.680 1.00 38.10 ? 20 VAL A CA 1 ATOM 139 C C . VAL A 1 19 ? -59.852 7.578 -25.664 1.00 36.07 ? 20 VAL A C 1 ATOM 140 O O . VAL A 1 19 ? -59.154 7.643 -24.694 1.00 38.70 ? 20 VAL A O 1 ATOM 141 C CB . VAL A 1 19 ? -60.775 9.856 -25.921 1.00 45.98 ? 20 VAL A CB 1 ATOM 142 C CG1 . VAL A 1 19 ? -59.713 10.050 -26.957 1.00 48.79 ? 20 VAL A CG1 1 ATOM 143 C CG2 . VAL A 1 19 ? -62.012 10.585 -26.353 1.00 47.85 ? 20 VAL A CG2 1 ATOM 144 N N . PRO A 1 20 ? -59.558 6.844 -26.751 1.00 35.56 ? 21 PRO A N 1 ATOM 145 C CA . PRO A 1 20 ? -58.320 6.011 -26.814 1.00 38.91 ? 21 PRO A CA 1 ATOM 146 C C . PRO A 1 20 ? -57.217 6.862 -27.332 1.00 38.92 ? 21 PRO A C 1 ATOM 147 O O . PRO A 1 20 ? -57.524 7.818 -28.089 1.00 39.35 ? 21 PRO A O 1 ATOM 148 C CB . PRO A 1 20 ? -58.668 4.913 -27.868 1.00 39.65 ? 21 PRO A CB 1 ATOM 149 C CG . PRO A 1 20 ? -59.712 5.604 -28.738 1.00 40.66 ? 21 PRO A CG 1 ATOM 150 C CD . PRO A 1 20 ? -60.516 6.511 -27.832 1.00 35.40 ? 21 PRO A CD 1 ATOM 151 N N . VAL A 1 21 ? -55.984 6.513 -26.950 1.00 33.90 ? 22 VAL A N 1 ATOM 152 C CA . VAL A 1 21 ? -54.800 7.282 -27.203 1.00 40.18 ? 22 VAL A CA 1 ATOM 153 C C . VAL A 1 21 ? -53.609 6.365 -27.075 1.00 41.51 ? 22 VAL A C 1 ATOM 154 O O . VAL A 1 21 ? -53.357 5.902 -25.966 1.00 41.05 ? 22 VAL A O 1 ATOM 155 C CB . VAL A 1 21 ? -54.490 8.346 -26.084 1.00 41.98 ? 22 VAL A CB 1 ATOM 156 C CG1 . VAL A 1 21 ? -53.351 9.253 -26.526 1.00 36.78 ? 22 VAL A CG1 1 ATOM 157 C CG2 . VAL A 1 21 ? -55.702 9.128 -25.720 1.00 51.33 ? 22 VAL A CG2 1 ATOM 158 N N . LEU A 1 22 ? -52.841 6.143 -28.148 1.00 47.20 ? 23 LEU A N 1 ATOM 159 C CA . LEU A 1 22 ? -51.616 5.341 -28.027 1.00 45.09 ? 23 LEU A CA 1 ATOM 160 C C . LEU A 1 22 ? -51.723 4.025 -27.141 1.00 45.67 ? 23 LEU A C 1 ATOM 161 O O . LEU A 1 22 ? -50.883 3.788 -26.245 1.00 42.12 ? 23 LEU A O 1 ATOM 162 C CB . LEU A 1 22 ? -50.543 6.247 -27.447 1.00 46.50 ? 23 LEU A CB 1 ATOM 163 C CG . LEU A 1 22 ? -50.156 7.464 -28.262 1.00 48.43 ? 23 LEU A CG 1 ATOM 164 C CD1 . LEU A 1 22 ? -49.045 8.190 -27.554 1.00 48.54 ? 23 LEU A CD1 1 ATOM 165 C CD2 . LEU A 1 22 ? -49.673 7.044 -29.648 1.00 51.40 ? 23 LEU A CD2 1 ATOM 166 N N . SER A 1 23 ? -52.764 3.219 -27.378 1.00 45.03 ? 24 SER A N 1 ATOM 167 C CA . SER A 1 23 ? -52.984 1.943 -26.631 1.00 57.00 ? 24 SER A CA 1 ATOM 168 C C . SER A 1 23 ? -53.305 2.183 -25.169 1.00 54.37 ? 24 SER A C 1 ATOM 169 O O . SER A 1 23 ? -52.787 1.511 -24.294 1.00 63.12 ? 24 SER A O 1 ATOM 170 C CB . SER A 1 23 ? -51.737 1.036 -26.675 1.00 56.69 ? 24 SER A CB 1 ATOM 171 O OG . SER A 1 23 ? -51.288 0.845 -27.998 1.00 69.74 ? 24 SER A OG 1 ATOM 172 N N . SER A 1 24 ? -54.092 3.199 -24.905 1.00 51.47 ? 25 SER A N 1 ATOM 173 C CA . SER A 1 24 ? -54.493 3.526 -23.551 1.00 42.91 ? 25 SER A CA 1 ATOM 174 C C . SER A 1 24 ? -55.689 4.402 -23.750 1.00 39.16 ? 25 SER A C 1 ATOM 175 O O . SER A 1 24 ? -56.292 4.390 -24.862 1.00 38.35 ? 25 SER A O 1 ATOM 176 C CB . SER A 1 24 ? -53.354 4.177 -22.769 1.00 43.37 ? 25 SER A CB 1 ATOM 177 O OG . SER A 1 24 ? -53.703 4.371 -21.409 1.00 47.30 ? 25 SER A OG 1 ATOM 178 N N . HIS A 1 25 ? -56.111 5.127 -22.732 1.00 39.45 ? 26 HIS A N 1 ATOM 179 C CA . HIS A 1 25 ? -57.336 5.892 -22.801 1.00 36.25 ? 26 HIS A CA 1 ATOM 180 C C . HIS A 1 25 ? -57.257 7.082 -21.882 1.00 40.20 ? 26 HIS A C 1 ATOM 181 O O . HIS A 1 25 ? -56.564 7.031 -20.928 1.00 40.65 ? 26 HIS A O 1 ATOM 182 C CB . HIS A 1 25 ? -58.498 5.037 -22.338 1.00 46.96 ? 26 HIS A CB 1 ATOM 183 C CG . HIS A 1 25 ? -58.922 3.985 -23.311 1.00 58.07 ? 26 HIS A CG 1 ATOM 184 N ND1 . HIS A 1 25 ? -58.283 2.774 -23.423 1.00 61.35 ? 26 HIS A ND1 1 ATOM 185 C CD2 . HIS A 1 25 ? -59.941 3.949 -24.193 1.00 64.74 ? 26 HIS A CD2 1 ATOM 186 C CE1 . HIS A 1 25 ? -58.869 2.051 -24.351 1.00 66.75 ? 26 HIS A CE1 1 ATOM 187 N NE2 . HIS A 1 25 ? -59.882 2.740 -24.829 1.00 68.46 ? 26 HIS A NE2 1 ATOM 188 N N . ILE A 1 26 ? -57.990 8.148 -22.171 1.00 41.65 ? 27 ILE A N 1 ATOM 189 C CA . ILE A 1 26 ? -58.160 9.277 -21.256 1.00 38.35 ? 27 ILE A CA 1 ATOM 190 C C . ILE A 1 26 ? -59.535 9.839 -21.386 1.00 34.63 ? 27 ILE A C 1 ATOM 191 O O . ILE A 1 26 ? -60.335 9.292 -22.146 1.00 35.77 ? 27 ILE A O 1 ATOM 192 C CB . ILE A 1 26 ? -57.121 10.396 -21.433 1.00 42.14 ? 27 ILE A CB 1 ATOM 193 C CG1 . ILE A 1 26 ? -57.255 11.057 -22.778 1.00 42.95 ? 27 ILE A CG1 1 ATOM 194 C CG2 . ILE A 1 26 ? -55.690 9.873 -21.225 1.00 41.60 ? 27 ILE A CG2 1 ATOM 195 C CD1 . ILE A 1 26 ? -56.450 12.319 -22.772 1.00 49.02 ? 27 ILE A CD1 1 ATOM 196 N N . SER A 1 27 ? -59.823 10.909 -20.653 1.00 32.48 ? 28 SER A N 1 ATOM 197 C CA . SER A 1 27 ? -61.140 11.531 -20.685 1.00 31.64 ? 28 SER A CA 1 ATOM 198 C C . SER A 1 27 ? -61.109 12.846 -21.455 1.00 33.48 ? 28 SER A C 1 ATOM 199 O O . SER A 1 27 ? -60.162 13.624 -21.339 1.00 35.03 ? 28 SER A O 1 ATOM 200 C CB . SER A 1 27 ? -61.656 11.766 -19.264 1.00 39.30 ? 28 SER A CB 1 ATOM 201 O OG . SER A 1 27 ? -61.337 10.675 -18.418 1.00 35.14 ? 28 SER A OG 1 ATOM 202 N N . ALA A 1 28 ? -62.152 13.085 -22.241 1.00 33.87 ? 29 ALA A N 1 ATOM 203 C CA . ALA A 1 28 ? -62.251 14.264 -23.012 1.00 35.81 ? 29 ALA A CA 1 ATOM 204 C C . ALA A 1 28 ? -63.593 14.922 -22.797 1.00 35.58 ? 29 ALA A C 1 ATOM 205 O O . ALA A 1 28 ? -64.629 14.266 -22.809 1.00 40.12 ? 29 ALA A O 1 ATOM 206 C CB . ALA A 1 28 ? -62.036 13.948 -24.495 1.00 39.59 ? 29 ALA A CB 1 ATOM 207 N N . PHE A 1 29 ? -63.558 16.233 -22.619 1.00 32.33 ? 30 PHE A N 1 ATOM 208 C CA . PHE A 1 29 ? -64.749 16.998 -22.404 1.00 34.80 ? 30 PHE A CA 1 ATOM 209 C C . PHE A 1 29 ? -64.735 18.056 -23.513 1.00 35.86 ? 30 PHE A C 1 ATOM 210 O O . PHE A 1 29 ? -64.000 19.048 -23.461 1.00 39.59 ? 30 PHE A O 1 ATOM 211 C CB . PHE A 1 29 ? -64.711 17.658 -21.001 1.00 33.43 ? 30 PHE A CB 1 ATOM 212 C CG . PHE A 1 29 ? -64.610 16.673 -19.860 1.00 31.47 ? 30 PHE A CG 1 ATOM 213 C CD1 . PHE A 1 29 ? -63.394 16.153 -19.491 1.00 30.11 ? 30 PHE A CD1 1 ATOM 214 C CD2 . PHE A 1 29 ? -65.759 16.270 -19.176 1.00 32.78 ? 30 PHE A CD2 1 ATOM 215 C CE1 . PHE A 1 29 ? -63.299 15.242 -18.449 1.00 37.19 ? 30 PHE A CE1 1 ATOM 216 C CE2 . PHE A 1 29 ? -65.683 15.374 -18.125 1.00 35.17 ? 30 PHE A CE2 1 ATOM 217 C CZ . PHE A 1 29 ? -64.450 14.832 -17.772 1.00 34.25 ? 30 PHE A CZ 1 ATOM 218 N N . LEU A 1 30 ? -65.541 17.827 -24.519 1.00 34.30 ? 31 LEU A N 1 ATOM 219 C CA . LEU A 1 30 ? -65.442 18.549 -25.743 1.00 35.21 ? 31 LEU A CA 1 ATOM 220 C C . LEU A 1 30 ? -66.631 19.419 -25.830 1.00 32.89 ? 31 LEU A C 1 ATOM 221 O O . LEU A 1 30 ? -67.734 18.998 -25.475 1.00 34.26 ? 31 LEU A O 1 ATOM 222 C CB . LEU A 1 30 ? -65.459 17.555 -26.910 1.00 38.27 ? 31 LEU A CB 1 ATOM 223 C CG . LEU A 1 30 ? -64.358 16.485 -26.896 1.00 37.12 ? 31 LEU A CG 1 ATOM 224 C CD1 . LEU A 1 30 ? -64.518 15.606 -28.138 1.00 36.79 ? 31 LEU A CD1 1 ATOM 225 C CD2 . LEU A 1 30 ? -62.954 17.061 -26.811 1.00 35.00 ? 31 LEU A CD2 1 ATOM 226 N N . GLY A 1 31 ? -66.428 20.650 -26.279 1.00 31.28 ? 32 GLY A N 1 ATOM 227 C CA . GLY A 1 31 ? -67.572 21.508 -26.591 1.00 30.39 ? 32 GLY A CA 1 ATOM 228 C C . GLY A 1 31 ? -68.273 22.033 -25.342 1.00 34.84 ? 32 GLY A C 1 ATOM 229 O O . GLY A 1 31 ? -69.488 22.175 -25.340 1.00 34.51 ? 32 GLY A O 1 ATOM 230 N N . ILE A 1 32 ? -67.502 22.395 -24.298 1.00 36.32 ? 33 ILE A N 1 ATOM 231 C CA . ILE A 1 32 ? -68.094 23.068 -23.115 1.00 35.34 ? 33 ILE A CA 1 ATOM 232 C C . ILE A 1 32 ? -68.269 24.548 -23.409 1.00 32.86 ? 33 ILE A C 1 ATOM 233 O O . ILE A 1 32 ? -67.332 25.200 -23.788 1.00 35.47 ? 33 ILE A O 1 ATOM 234 C CB . ILE A 1 32 ? -67.206 22.924 -21.852 1.00 33.94 ? 33 ILE A CB 1 ATOM 235 C CG1 . ILE A 1 32 ? -67.047 21.467 -21.491 1.00 34.56 ? 33 ILE A CG1 1 ATOM 236 C CG2 . ILE A 1 32 ? -67.848 23.654 -20.678 1.00 36.57 ? 33 ILE A CG2 1 ATOM 237 C CD1 . ILE A 1 32 ? -65.975 21.198 -20.464 1.00 34.84 ? 33 ILE A CD1 1 ATOM 238 N N . PRO A 1 33 ? -69.444 25.107 -23.160 1.00 31.78 ? 34 PRO A N 1 ATOM 239 C CA . PRO A 1 33 ? -69.643 26.499 -23.450 1.00 30.41 ? 34 PRO A CA 1 ATOM 240 C C . PRO A 1 33 ? -69.129 27.418 -22.330 1.00 32.03 ? 34 PRO A C 1 ATOM 241 O O . PRO A 1 33 ? -69.300 27.101 -21.148 1.00 36.59 ? 34 PRO A O 1 ATOM 242 C CB . PRO A 1 33 ? -71.155 26.590 -23.564 1.00 31.28 ? 34 PRO A CB 1 ATOM 243 C CG . PRO A 1 33 ? -71.659 25.555 -22.663 1.00 28.48 ? 34 PRO A CG 1 ATOM 244 C CD . PRO A 1 33 ? -70.689 24.449 -22.740 1.00 31.43 ? 34 PRO A CD 1 ATOM 245 N N . PHE A 1 34 ? -68.482 28.521 -22.696 1.00 30.45 ? 35 PHE A N 1 ATOM 246 C CA . PHE A 1 34 ? -67.898 29.426 -21.699 1.00 27.47 ? 35 PHE A CA 1 ATOM 247 C C . PHE A 1 34 ? -68.438 30.814 -21.826 1.00 28.34 ? 35 PHE A C 1 ATOM 248 O O . PHE A 1 34 ? -68.115 31.670 -20.990 1.00 31.44 ? 35 PHE A O 1 ATOM 249 C CB . PHE A 1 34 ? -66.351 29.419 -21.719 1.00 32.32 ? 35 PHE A CB 1 ATOM 250 C CG . PHE A 1 34 ? -65.741 29.976 -22.994 1.00 31.23 ? 35 PHE A CG 1 ATOM 251 C CD1 . PHE A 1 34 ? -65.744 31.347 -23.249 1.00 31.44 ? 35 PHE A CD1 1 ATOM 252 C CD2 . PHE A 1 34 ? -65.266 29.127 -23.980 1.00 30.70 ? 35 PHE A CD2 1 ATOM 253 C CE1 . PHE A 1 34 ? -65.226 31.856 -24.422 1.00 31.17 ? 35 PHE A CE1 1 ATOM 254 C CE2 . PHE A 1 34 ? -64.775 29.643 -25.172 1.00 32.31 ? 35 PHE A CE2 1 ATOM 255 C CZ . PHE A 1 34 ? -64.731 30.999 -25.379 1.00 31.11 ? 35 PHE A CZ 1 ATOM 256 N N . ALA A 1 35 ? -69.324 31.065 -22.799 1.00 27.81 ? 36 ALA A N 1 ATOM 257 C CA . ALA A 1 35 ? -69.926 32.371 -22.937 1.00 26.50 ? 36 ALA A CA 1 ATOM 258 C C . ALA A 1 35 ? -71.301 32.179 -23.470 1.00 31.10 ? 36 ALA A C 1 ATOM 259 O O . ALA A 1 35 ? -71.576 31.156 -24.034 1.00 29.43 ? 36 ALA A O 1 ATOM 260 C CB . ALA A 1 35 ? -69.083 33.208 -23.931 1.00 28.12 ? 36 ALA A CB 1 ATOM 261 N N . GLU A 1 36 ? -72.173 33.170 -23.357 1.00 32.55 ? 37 GLU A N 1 ATOM 262 C CA . GLU A 1 36 ? -73.416 33.119 -24.137 1.00 33.88 ? 37 GLU A CA 1 ATOM 263 C C . GLU A 1 36 ? -73.104 33.195 -25.662 1.00 36.28 ? 37 GLU A C 1 ATOM 264 O O . GLU A 1 36 ? -72.187 33.914 -26.052 1.00 34.85 ? 37 GLU A O 1 ATOM 265 C CB . GLU A 1 36 ? -74.276 34.362 -23.767 1.00 35.36 ? 37 GLU A CB 1 ATOM 266 C CG . GLU A 1 36 ? -75.017 34.263 -22.406 1.00 39.37 ? 37 GLU A CG 1 ATOM 267 C CD . GLU A 1 36 ? -75.873 33.005 -22.322 1.00 40.60 ? 37 GLU A CD 1 ATOM 268 O OE1 . GLU A 1 36 ? -76.789 32.944 -23.108 1.00 40.74 ? 37 GLU A OE1 1 ATOM 269 O OE2 . GLU A 1 36 ? -75.605 32.043 -21.557 1.00 41.93 ? 37 GLU A OE2 1 ATOM 270 N N . PRO A 1 37 ? -73.903 32.541 -26.522 1.00 37.03 ? 38 PRO A N 1 ATOM 271 C CA . PRO A 1 37 ? -73.790 32.728 -27.971 1.00 34.43 ? 38 PRO A CA 1 ATOM 272 C C . PRO A 1 37 ? -73.834 34.182 -28.430 1.00 37.28 ? 38 PRO A C 1 ATOM 273 O O . PRO A 1 37 ? -74.811 34.870 -28.211 1.00 39.66 ? 38 PRO A O 1 ATOM 274 C CB . PRO A 1 37 ? -75.046 32.000 -28.516 1.00 37.85 ? 38 PRO A CB 1 ATOM 275 C CG . PRO A 1 37 ? -75.295 30.906 -27.515 1.00 37.36 ? 38 PRO A CG 1 ATOM 276 C CD . PRO A 1 37 ? -74.967 31.556 -26.188 1.00 37.73 ? 38 PRO A CD 1 ATOM 277 N N . PRO A 1 38 ? -72.785 34.659 -29.109 1.00 35.93 ? 39 PRO A N 1 ATOM 278 C CA . PRO A 1 38 ? -72.750 36.032 -29.481 1.00 35.59 ? 39 PRO A CA 1 ATOM 279 C C . PRO A 1 38 ? -73.475 36.312 -30.798 1.00 42.63 ? 39 PRO A C 1 ATOM 280 O O . PRO A 1 38 ? -72.862 36.733 -31.792 1.00 40.69 ? 39 PRO A O 1 ATOM 281 C CB . PRO A 1 38 ? -71.281 36.299 -29.563 1.00 37.27 ? 39 PRO A CB 1 ATOM 282 C CG . PRO A 1 38 ? -70.698 35.002 -29.983 1.00 36.37 ? 39 PRO A CG 1 ATOM 283 C CD . PRO A 1 38 ? -71.605 33.934 -29.564 1.00 34.76 ? 39 PRO A CD 1 ATOM 284 N N . VAL A 1 39 ? -74.795 36.116 -30.767 1.00 40.89 ? 40 VAL A N 1 ATOM 285 C CA . VAL A 1 39 ? -75.605 36.112 -31.962 1.00 36.33 ? 40 VAL A CA 1 ATOM 286 C C . VAL A 1 39 ? -76.595 37.256 -31.915 1.00 42.07 ? 40 VAL A C 1 ATOM 287 O O . VAL A 1 39 ? -76.764 37.930 -30.902 1.00 42.95 ? 40 VAL A O 1 ATOM 288 C CB . VAL A 1 39 ? -76.323 34.785 -32.157 1.00 40.07 ? 40 VAL A CB 1 ATOM 289 C CG1 . VAL A 1 39 ? -75.311 33.654 -32.244 1.00 41.05 ? 40 VAL A CG1 1 ATOM 290 C CG2 . VAL A 1 39 ? -77.290 34.506 -31.011 1.00 40.89 ? 40 VAL A CG2 1 ATOM 291 N N . GLY A 1 40 ? -77.213 37.496 -33.058 1.00 42.42 ? 41 GLY A N 1 ATOM 292 C CA . GLY A 1 40 ? -78.070 38.634 -33.257 1.00 39.80 ? 41 GLY A CA 1 ATOM 293 C C . GLY A 1 40 ? -77.443 39.936 -32.838 1.00 41.55 ? 41 GLY A C 1 ATOM 294 O O . GLY A 1 40 ? -76.378 40.349 -33.350 1.00 44.99 ? 41 GLY A O 1 ATOM 295 N N . ASN A 1 41 ? -78.121 40.593 -31.906 1.00 41.71 ? 42 ASN A N 1 ATOM 296 C CA . ASN A 1 41 ? -77.738 41.886 -31.408 1.00 40.31 ? 42 ASN A CA 1 ATOM 297 C C . ASN A 1 41 ? -76.470 41.871 -30.578 1.00 35.35 ? 42 ASN A C 1 ATOM 298 O O . ASN A 1 41 ? -75.907 42.920 -30.322 1.00 35.88 ? 42 ASN A O 1 ATOM 299 C CB . ASN A 1 41 ? -78.899 42.546 -30.679 1.00 53.06 ? 42 ASN A CB 1 ATOM 300 C CG . ASN A 1 41 ? -79.845 43.248 -31.662 1.00 74.46 ? 42 ASN A CG 1 ATOM 301 O OD1 . ASN A 1 41 ? -79.796 43.012 -32.911 1.00 84.81 ? 42 ASN A OD1 1 ATOM 302 N ND2 . ASN A 1 41 ? -80.683 44.143 -31.128 1.00 76.59 ? 42 ASN A ND2 1 ATOM 303 N N . MET A 1 42 ? -76.000 40.703 -30.211 1.00 30.01 ? 43 MET A N 1 ATOM 304 C CA . MET A 1 42 ? -74.670 40.576 -29.581 1.00 38.94 ? 43 MET A CA 1 ATOM 305 C C . MET A 1 42 ? -73.437 40.391 -30.552 1.00 36.26 ? 43 MET A C 1 ATOM 306 O O . MET A 1 42 ? -72.237 40.294 -30.111 1.00 35.04 ? 43 MET A O 1 ATOM 307 C CB . MET A 1 42 ? -74.704 39.400 -28.620 1.00 46.15 ? 43 MET A CB 1 ATOM 308 C CG . MET A 1 42 ? -75.879 39.451 -27.639 1.00 54.22 ? 43 MET A CG 1 ATOM 309 S SD . MET A 1 42 ? -75.424 38.402 -26.248 1.00 73.86 ? 43 MET A SD 1 ATOM 310 C CE . MET A 1 42 ? -74.584 39.757 -25.398 1.00 72.53 ? 43 MET A CE 1 ATOM 311 N N . ARG A 1 43 ? -73.719 40.356 -31.848 1.00 32.63 ? 44 ARG A N 1 ATOM 312 C CA . ARG A 1 43 ? -72.673 40.269 -32.861 1.00 31.81 ? 44 ARG A CA 1 ATOM 313 C C . ARG A 1 43 ? -71.859 41.561 -32.700 1.00 31.28 ? 44 ARG A C 1 ATOM 314 O O . ARG A 1 43 ? -72.412 42.622 -32.490 1.00 33.97 ? 44 ARG A O 1 ATOM 315 C CB . ARG A 1 43 ? -73.249 40.042 -34.288 1.00 33.44 ? 44 ARG A CB 1 ATOM 316 C CG . ARG A 1 43 ? -72.173 40.153 -35.363 1.00 37.91 ? 44 ARG A CG 1 ATOM 317 C CD . ARG A 1 43 ? -72.697 40.249 -36.779 1.00 33.43 ? 44 ARG A CD 1 ATOM 318 N NE . ARG A 1 43 ? -73.173 38.980 -37.274 1.00 32.35 ? 44 ARG A NE 1 ATOM 319 C CZ . ARG A 1 43 ? -73.842 38.865 -38.407 1.00 32.50 ? 44 ARG A CZ 1 ATOM 320 N NH1 . ARG A 1 43 ? -74.069 39.936 -39.175 1.00 31.82 ? 44 ARG A NH1 1 ATOM 321 N NH2 . ARG A 1 43 ? -74.273 37.667 -38.799 1.00 36.30 ? 44 ARG A NH2 1 ATOM 322 N N . PHE A 1 44 ? -70.545 41.403 -32.634 1.00 31.07 ? 45 PHE A N 1 ATOM 323 C CA . PHE A 1 44 ? -69.576 42.459 -32.398 1.00 32.33 ? 45 PHE A CA 1 ATOM 324 C C . PHE A 1 44 ? -69.443 42.927 -30.980 1.00 32.26 ? 45 PHE A C 1 ATOM 325 O O . PHE A 1 44 ? -68.482 43.647 -30.679 1.00 34.22 ? 45 PHE A O 1 ATOM 326 C CB . PHE A 1 44 ? -69.788 43.684 -33.294 1.00 34.17 ? 45 PHE A CB 1 ATOM 327 C CG . PHE A 1 44 ? -70.038 43.374 -34.746 1.00 38.12 ? 45 PHE A CG 1 ATOM 328 C CD1 . PHE A 1 44 ? -69.129 42.635 -35.487 1.00 39.45 ? 45 PHE A CD1 1 ATOM 329 C CD2 . PHE A 1 44 ? -71.180 43.897 -35.396 1.00 44.07 ? 45 PHE A CD2 1 ATOM 330 C CE1 . PHE A 1 44 ? -69.355 42.394 -36.832 1.00 42.47 ? 45 PHE A CE1 1 ATOM 331 C CE2 . PHE A 1 44 ? -71.409 43.672 -36.745 1.00 43.75 ? 45 PHE A CE2 1 ATOM 332 C CZ . PHE A 1 44 ? -70.491 42.920 -37.464 1.00 45.58 ? 45 PHE A CZ 1 ATOM 333 N N . ARG A 1 45 ? -70.346 42.503 -30.104 1.00 36.90 ? 46 ARG A N 1 ATOM 334 C CA . ARG A 1 45 ? -70.321 42.906 -28.685 1.00 40.84 ? 46 ARG A CA 1 ATOM 335 C C . ARG A 1 45 ? -69.312 42.094 -27.883 1.00 38.00 ? 46 ARG A C 1 ATOM 336 O O . ARG A 1 45 ? -68.905 40.985 -28.286 1.00 37.73 ? 46 ARG A O 1 ATOM 337 C CB . ARG A 1 45 ? -71.697 42.712 -28.017 1.00 46.56 ? 46 ARG A CB 1 ATOM 338 C CG . ARG A 1 45 ? -72.593 43.935 -28.079 1.00 53.78 ? 46 ARG A CG 1 ATOM 339 C CD . ARG A 1 45 ? -73.829 43.762 -27.215 1.00 54.93 ? 46 ARG A CD 1 ATOM 340 N NE . ARG A 1 45 ? -74.120 44.999 -26.488 1.00 67.64 ? 46 ARG A NE 1 ATOM 341 C CZ . ARG A 1 45 ? -73.559 45.361 -25.327 1.00 70.17 ? 46 ARG A CZ 1 ATOM 342 N NH1 . ARG A 1 45 ? -72.657 44.587 -24.731 1.00 76.12 ? 46 ARG A NH1 1 ATOM 343 N NH2 . ARG A 1 45 ? -73.891 46.514 -24.755 1.00 72.91 ? 46 ARG A NH2 1 ATOM 344 N N . ARG A 1 46 ? -68.910 42.630 -26.734 1.00 33.94 ? 47 ARG A N 1 ATOM 345 C CA . ARG A 1 46 ? -68.039 41.901 -25.821 1.00 37.13 ? 47 ARG A CA 1 ATOM 346 C C . ARG A 1 46 ? -68.824 40.739 -25.225 1.00 31.16 ? 47 ARG A C 1 ATOM 347 O O . ARG A 1 46 ? -69.979 40.904 -24.831 1.00 32.82 ? 47 ARG A O 1 ATOM 348 C CB . ARG A 1 46 ? -67.530 42.822 -24.711 1.00 45.63 ? 47 ARG A CB 1 ATOM 349 C CG . ARG A 1 46 ? -68.549 43.101 -23.619 1.00 63.23 ? 47 ARG A CG 1 ATOM 350 C CD . ARG A 1 46 ? -68.463 44.541 -23.138 1.00 71.23 ? 47 ARG A CD 1 ATOM 351 N NE . ARG A 1 46 ? -67.101 45.061 -23.209 1.00 77.51 ? 47 ARG A NE 1 ATOM 352 C CZ . ARG A 1 46 ? -66.754 46.161 -23.868 1.00 69.98 ? 47 ARG A CZ 1 ATOM 353 N NH1 . ARG A 1 46 ? -67.672 46.864 -24.518 1.00 63.88 ? 47 ARG A NH1 1 ATOM 354 N NH2 . ARG A 1 46 ? -65.490 46.560 -23.879 1.00 58.59 ? 47 ARG A NH2 1 ATOM 355 N N . PRO A 1 47 ? -68.208 39.563 -25.168 1.00 31.22 ? 48 PRO A N 1 ATOM 356 C CA . PRO A 1 47 ? -68.917 38.382 -24.731 1.00 32.01 ? 48 PRO A CA 1 ATOM 357 C C . PRO A 1 47 ? -69.585 38.512 -23.326 1.00 34.66 ? 48 PRO A C 1 ATOM 358 O O . PRO A 1 47 ? -69.068 39.231 -22.495 1.00 33.05 ? 48 PRO A O 1 ATOM 359 C CB . PRO A 1 47 ? -67.801 37.372 -24.666 1.00 27.51 ? 48 PRO A CB 1 ATOM 360 C CG . PRO A 1 47 ? -66.606 38.160 -24.290 1.00 26.76 ? 48 PRO A CG 1 ATOM 361 C CD . PRO A 1 47 ? -66.746 39.372 -25.136 1.00 28.50 ? 48 PRO A CD 1 ATOM 362 N N . GLU A 1 48 ? -70.713 37.825 -23.121 1.00 40.34 ? 49 GLU A N 1 ATOM 363 C CA . GLU A 1 48 ? -71.334 37.628 -21.796 1.00 43.66 ? 49 GLU A CA 1 ATOM 364 C C . GLU A 1 48 ? -71.011 36.212 -21.270 1.00 36.40 ? 49 GLU A C 1 ATOM 365 O O . GLU A 1 48 ? -70.981 35.254 -22.030 1.00 36.61 ? 49 GLU A O 1 ATOM 366 C CB . GLU A 1 48 ? -72.868 37.877 -21.835 1.00 45.76 ? 49 GLU A CB 1 ATOM 367 C CG . GLU A 1 48 ? -73.314 39.329 -22.196 1.00 54.89 ? 49 GLU A CG 1 ATOM 368 C CD . GLU A 1 48 ? -72.507 40.457 -21.521 1.00 65.56 ? 49 GLU A CD 1 ATOM 369 O OE1 . GLU A 1 48 ? -72.352 40.442 -20.277 1.00 84.90 ? 49 GLU A OE1 1 ATOM 370 O OE2 . GLU A 1 48 ? -72.029 41.385 -22.227 1.00 78.15 ? 49 GLU A OE2 1 ATOM 371 N N . PRO A 1 49 ? -70.810 36.061 -19.955 1.00 35.74 ? 50 PRO A N 1 ATOM 372 C CA . PRO A 1 49 ? -70.548 34.719 -19.419 1.00 36.69 ? 50 PRO A CA 1 ATOM 373 C C . PRO A 1 49 ? -71.718 33.789 -19.617 1.00 33.47 ? 50 PRO A C 1 ATOM 374 O O . PRO A 1 49 ? -72.861 34.237 -19.647 1.00 30.91 ? 50 PRO A O 1 ATOM 375 C CB . PRO A 1 49 ? -70.275 34.965 -17.916 1.00 39.19 ? 50 PRO A CB 1 ATOM 376 C CG . PRO A 1 49 ? -70.953 36.249 -17.608 1.00 40.38 ? 50 PRO A CG 1 ATOM 377 C CD . PRO A 1 49 ? -70.867 37.082 -18.888 1.00 41.38 ? 50 PRO A CD 1 ATOM 378 N N . LYS A 1 50 ? -71.426 32.511 -19.805 1.00 33.90 ? 51 LYS A N 1 ATOM 379 C CA . LYS A 1 50 ? -72.470 31.505 -19.995 1.00 39.10 ? 51 LYS A CA 1 ATOM 380 C C . LYS A 1 50 ? -73.356 31.290 -18.706 1.00 40.61 ? 51 LYS A C 1 ATOM 381 O O . LYS A 1 50 ? -72.838 31.005 -17.654 1.00 35.40 ? 51 LYS A O 1 ATOM 382 C CB . LYS A 1 50 ? -71.802 30.194 -20.356 1.00 40.64 ? 51 LYS A CB 1 ATOM 383 C CG . LYS A 1 50 ? -72.753 29.017 -20.536 1.00 40.81 ? 51 LYS A CG 1 ATOM 384 C CD . LYS A 1 50 ? -73.808 29.291 -21.594 1.00 35.93 ? 51 LYS A CD 1 ATOM 385 C CE . LYS A 1 50 ? -74.517 27.989 -21.910 1.00 38.25 ? 51 LYS A CE 1 ATOM 386 N NZ . LYS A 1 50 ? -75.541 28.202 -22.961 1.00 40.30 ? 51 LYS A NZ 1 ATOM 387 N N . LYS A 1 51 ? -74.663 31.480 -18.841 1.00 41.59 ? 52 LYS A N 1 ATOM 388 C CA . LYS A 1 51 ? -75.623 31.245 -17.786 1.00 44.33 ? 52 LYS A CA 1 ATOM 389 C C . LYS A 1 51 ? -75.596 29.785 -17.418 1.00 40.24 ? 52 LYS A C 1 ATOM 390 O O . LYS A 1 51 ? -75.628 28.914 -18.261 1.00 39.25 ? 52 LYS A O 1 ATOM 391 C CB . LYS A 1 51 ? -77.020 31.673 -18.198 1.00 51.79 ? 52 LYS A CB 1 ATOM 392 C CG . LYS A 1 51 ? -77.096 33.182 -18.430 1.00 66.43 ? 52 LYS A CG 1 ATOM 393 C CD . LYS A 1 51 ? -78.454 33.675 -18.928 1.00 78.59 ? 52 LYS A CD 1 ATOM 394 C CE . LYS A 1 51 ? -78.941 32.913 -20.162 1.00 80.44 ? 52 LYS A CE 1 ATOM 395 N NZ . LYS A 1 51 ? -79.870 33.754 -20.966 1.00 83.53 ? 52 LYS A NZ 1 ATOM 396 N N . PRO A 1 52 ? -75.478 29.513 -16.132 1.00 41.79 ? 53 PRO A N 1 ATOM 397 C CA . PRO A 1 52 ? -75.342 28.126 -15.714 1.00 42.42 ? 53 PRO A CA 1 ATOM 398 C C . PRO A 1 52 ? -76.554 27.332 -16.126 1.00 41.33 ? 53 PRO A C 1 ATOM 399 O O . PRO A 1 52 ? -77.635 27.890 -16.386 1.00 40.26 ? 53 PRO A O 1 ATOM 400 C CB . PRO A 1 52 ? -75.251 28.234 -14.202 1.00 44.04 ? 53 PRO A CB 1 ATOM 401 C CG . PRO A 1 52 ? -74.785 29.656 -13.954 1.00 44.12 ? 53 PRO A CG 1 ATOM 402 C CD . PRO A 1 52 ? -75.528 30.437 -14.987 1.00 38.97 ? 53 PRO A CD 1 ATOM 403 N N . TRP A 1 53 ? -76.360 26.046 -16.249 1.00 42.18 ? 54 TRP A N 1 ATOM 404 C CA . TRP A 1 53 ? -77.423 25.179 -16.799 1.00 44.88 ? 54 TRP A CA 1 ATOM 405 C C . TRP A 1 53 ? -77.823 24.094 -15.786 1.00 46.76 ? 54 TRP A C 1 ATOM 406 O O . TRP A 1 53 ? -76.999 23.658 -14.941 1.00 43.33 ? 54 TRP A O 1 ATOM 407 C CB . TRP A 1 53 ? -76.984 24.537 -18.153 1.00 38.57 ? 54 TRP A CB 1 ATOM 408 C CG . TRP A 1 53 ? -75.766 23.759 -18.042 1.00 32.41 ? 54 TRP A CG 1 ATOM 409 C CD1 . TRP A 1 53 ? -75.667 22.495 -17.635 1.00 35.71 ? 54 TRP A CD1 1 ATOM 410 C CD2 . TRP A 1 53 ? -74.437 24.213 -18.275 1.00 34.68 ? 54 TRP A CD2 1 ATOM 411 N NE1 . TRP A 1 53 ? -74.344 22.102 -17.587 1.00 34.84 ? 54 TRP A NE1 1 ATOM 412 C CE2 . TRP A 1 53 ? -73.578 23.157 -17.988 1.00 32.36 ? 54 TRP A CE2 1 ATOM 413 C CE3 . TRP A 1 53 ? -73.891 25.423 -18.713 1.00 34.94 ? 54 TRP A CE3 1 ATOM 414 C CZ2 . TRP A 1 53 ? -72.225 23.256 -18.143 1.00 37.06 ? 54 TRP A CZ2 1 ATOM 415 C CZ3 . TRP A 1 53 ? -72.576 25.527 -18.870 1.00 33.32 ? 54 TRP A CZ3 1 ATOM 416 C CH2 . TRP A 1 53 ? -71.735 24.458 -18.605 1.00 38.95 ? 54 TRP A CH2 1 ATOM 417 N N . SER A 1 54 ? -79.089 23.684 -15.888 1.00 54.16 ? 55 SER A N 1 ATOM 418 C CA . SER A 1 54 ? -79.621 22.512 -15.194 1.00 59.83 ? 55 SER A CA 1 ATOM 419 C C . SER A 1 54 ? -79.279 21.297 -16.018 1.00 59.52 ? 55 SER A C 1 ATOM 420 O O . SER A 1 54 ? -79.058 21.398 -17.235 1.00 57.39 ? 55 SER A O 1 ATOM 421 C CB . SER A 1 54 ? -81.149 22.574 -15.094 1.00 58.59 ? 55 SER A CB 1 ATOM 422 O OG . SER A 1 54 ? -81.537 23.606 -14.195 1.00 66.62 ? 55 SER A OG 1 ATOM 423 N N . GLY A 1 55 ? -79.265 20.145 -15.368 1.00 54.19 ? 56 GLY A N 1 ATOM 424 C CA . GLY A 1 55 ? -78.976 18.916 -16.081 1.00 50.57 ? 56 GLY A CA 1 ATOM 425 C C . GLY A 1 55 ? -77.497 18.813 -16.421 1.00 48.93 ? 56 GLY A C 1 ATOM 426 O O . GLY A 1 55 ? -76.658 19.555 -15.887 1.00 44.50 ? 56 GLY A O 1 ATOM 427 N N . VAL A 1 56 ? -77.227 17.878 -17.328 1.00 45.51 ? 57 VAL A N 1 ATOM 428 C CA . VAL A 1 56 ? -75.912 17.389 -17.705 1.00 41.81 ? 57 VAL A CA 1 ATOM 429 C C . VAL A 1 56 ? -75.598 17.776 -19.173 1.00 41.30 ? 57 VAL A C 1 ATOM 430 O O . VAL A 1 56 ? -76.324 17.426 -20.079 1.00 38.59 ? 57 VAL A O 1 ATOM 431 C CB . VAL A 1 56 ? -75.850 15.874 -17.506 1.00 41.36 ? 57 VAL A CB 1 ATOM 432 C CG1 . VAL A 1 56 ? -74.522 15.332 -18.012 1.00 44.34 ? 57 VAL A CG1 1 ATOM 433 C CG2 . VAL A 1 56 ? -76.041 15.540 -15.995 1.00 39.92 ? 57 VAL A CG2 1 ATOM 434 N N . TRP A 1 57 ? -74.532 18.557 -19.359 1.00 39.85 ? 58 TRP A N 1 ATOM 435 C CA . TRP A 1 57 ? -74.168 19.114 -20.636 1.00 38.12 ? 58 TRP A CA 1 ATOM 436 C C . TRP A 1 57 ? -73.401 17.990 -21.260 1.00 36.52 ? 58 TRP A C 1 ATOM 437 O O . TRP A 1 57 ? -72.411 17.523 -20.663 1.00 33.52 ? 58 TRP A O 1 ATOM 438 C CB . TRP A 1 57 ? -73.256 20.356 -20.505 1.00 41.41 ? 58 TRP A CB 1 ATOM 439 C CG . TRP A 1 57 ? -72.960 20.900 -21.842 1.00 39.07 ? 58 TRP A CG 1 ATOM 440 C CD1 . TRP A 1 57 ? -72.031 20.417 -22.737 1.00 33.25 ? 58 TRP A CD1 1 ATOM 441 C CD2 . TRP A 1 57 ? -73.645 21.950 -22.489 1.00 32.59 ? 58 TRP A CD2 1 ATOM 442 N NE1 . TRP A 1 57 ? -72.117 21.097 -23.867 1.00 32.99 ? 58 TRP A NE1 1 ATOM 443 C CE2 . TRP A 1 57 ? -73.105 22.046 -23.768 1.00 34.75 ? 58 TRP A CE2 1 ATOM 444 C CE3 . TRP A 1 57 ? -74.662 22.834 -22.101 1.00 36.89 ? 58 TRP A CE3 1 ATOM 445 C CZ2 . TRP A 1 57 ? -73.506 23.021 -24.676 1.00 32.74 ? 58 TRP A CZ2 1 ATOM 446 C CZ3 . TRP A 1 57 ? -75.108 23.787 -22.992 1.00 34.67 ? 58 TRP A CZ3 1 ATOM 447 C CH2 . TRP A 1 57 ? -74.525 23.877 -24.283 1.00 39.32 ? 58 TRP A CH2 1 ATOM 448 N N . ASN A 1 58 ? -73.889 17.531 -22.425 1.00 34.39 ? 59 ASN A N 1 ATOM 449 C CA . ASN A 1 58 ? -73.269 16.418 -23.159 1.00 36.90 ? 59 ASN A CA 1 ATOM 450 C C . ASN A 1 58 ? -71.974 17.001 -23.760 1.00 37.97 ? 59 ASN A C 1 ATOM 451 O O . ASN A 1 58 ? -72.048 17.902 -24.552 1.00 38.09 ? 59 ASN A O 1 ATOM 452 C CB . ASN A 1 58 ? -74.226 15.826 -24.270 1.00 33.91 ? 59 ASN A CB 1 ATOM 453 C CG . ASN A 1 58 ? -73.623 14.598 -25.009 1.00 45.01 ? 59 ASN A CG 1 ATOM 454 O OD1 . ASN A 1 58 ? -72.418 14.301 -24.833 1.00 43.96 ? 59 ASN A OD1 1 ATOM 455 N ND2 . ASN A 1 58 ? -74.471 13.867 -25.863 1.00 59.44 ? 59 ASN A ND2 1 ATOM 456 N N . ALA A 1 59 ? -70.812 16.514 -23.362 1.00 36.64 ? 60 ALA A N 1 ATOM 457 C CA . ALA A 1 59 ? -69.548 17.070 -23.845 1.00 33.59 ? 60 ALA A CA 1 ATOM 458 C C . ALA A 1 59 ? -68.772 15.967 -24.500 1.00 33.68 ? 60 ALA A C 1 ATOM 459 O O . ALA A 1 59 ? -67.571 15.809 -24.269 1.00 35.07 ? 60 ALA A O 1 ATOM 460 C CB . ALA A 1 59 ? -68.748 17.617 -22.702 1.00 30.79 ? 60 ALA A CB 1 ATOM 461 N N . SER A 1 60 ? -69.458 15.205 -25.342 1.00 35.91 ? 61 SER A N 1 ATOM 462 C CA . SER A 1 60 ? -68.826 14.052 -25.992 1.00 39.85 ? 61 SER A CA 1 ATOM 463 C C . SER A 1 60 ? -68.386 14.383 -27.417 1.00 35.20 ? 61 SER A C 1 ATOM 464 O O . SER A 1 60 ? -67.552 13.685 -27.958 1.00 32.39 ? 61 SER A O 1 ATOM 465 C CB . SER A 1 60 ? -69.753 12.848 -25.937 1.00 38.81 ? 61 SER A CB 1 ATOM 466 O OG . SER A 1 60 ? -70.969 13.265 -26.470 1.00 40.09 ? 61 SER A OG 1 ATOM 467 N N . THR A 1 61 ? -68.869 15.491 -27.980 1.00 38.79 ? 62 THR A N 1 ATOM 468 C CA . THR A 1 61 ? -68.449 15.846 -29.332 1.00 42.42 ? 62 THR A CA 1 ATOM 469 C C . THR A 1 61 ? -68.044 17.311 -29.490 1.00 38.65 ? 62 THR A C 1 ATOM 470 O O . THR A 1 61 ? -68.513 18.194 -28.804 1.00 39.49 ? 62 THR A O 1 ATOM 471 C CB . THR A 1 61 ? -69.519 15.507 -30.375 1.00 47.00 ? 62 THR A CB 1 ATOM 472 O OG1 . THR A 1 61 ? -70.693 16.272 -30.101 1.00 43.32 ? 62 THR A OG1 1 ATOM 473 C CG2 . THR A 1 61 ? -69.843 13.979 -30.341 1.00 53.91 ? 62 THR A CG2 1 ATOM 474 N N . TYR A 1 62 ? -67.132 17.507 -30.420 1.00 34.10 ? 63 TYR A N 1 ATOM 475 C CA . TYR A 1 62 ? -66.581 18.803 -30.764 1.00 33.47 ? 63 TYR A CA 1 ATOM 476 C C . TYR A 1 62 ? -67.662 19.798 -31.132 1.00 32.36 ? 63 TYR A C 1 ATOM 477 O O . TYR A 1 62 ? -68.684 19.467 -31.648 1.00 37.39 ? 63 TYR A O 1 ATOM 478 C CB . TYR A 1 62 ? -65.619 18.655 -31.929 1.00 29.37 ? 63 TYR A CB 1 ATOM 479 C CG . TYR A 1 62 ? -64.216 18.258 -31.635 1.00 28.91 ? 63 TYR A CG 1 ATOM 480 C CD1 . TYR A 1 62 ? -63.515 18.825 -30.577 1.00 30.34 ? 63 TYR A CD1 1 ATOM 481 C CD2 . TYR A 1 62 ? -63.514 17.379 -32.497 1.00 31.17 ? 63 TYR A CD2 1 ATOM 482 C CE1 . TYR A 1 62 ? -62.145 18.560 -30.386 1.00 27.05 ? 63 TYR A CE1 1 ATOM 483 C CE2 . TYR A 1 62 ? -62.115 17.078 -32.307 1.00 27.95 ? 63 TYR A CE2 1 ATOM 484 C CZ . TYR A 1 62 ? -61.446 17.711 -31.258 1.00 29.73 ? 63 TYR A CZ 1 ATOM 485 O OH . TYR A 1 62 ? -60.112 17.439 -30.996 1.00 31.22 ? 63 TYR A OH 1 ATOM 486 N N . PRO A 1 63 ? -67.471 21.034 -30.756 1.00 28.72 ? 64 PRO A N 1 ATOM 487 C CA . PRO A 1 63 ? -68.412 22.030 -31.076 1.00 27.88 ? 64 PRO A CA 1 ATOM 488 C C . PRO A 1 63 ? -68.218 22.518 -32.538 1.00 29.43 ? 64 PRO A C 1 ATOM 489 O O . PRO A 1 63 ? -67.293 22.101 -33.217 1.00 29.84 ? 64 PRO A O 1 ATOM 490 C CB . PRO A 1 63 ? -67.972 23.165 -30.146 1.00 27.99 ? 64 PRO A CB 1 ATOM 491 C CG . PRO A 1 63 ? -66.483 23.065 -30.121 1.00 26.25 ? 64 PRO A CG 1 ATOM 492 C CD . PRO A 1 63 ? -66.263 21.577 -30.108 1.00 29.82 ? 64 PRO A CD 1 ATOM 493 N N . ASN A 1 64 ? -69.074 23.426 -32.935 1.00 26.97 ? 65 ASN A N 1 ATOM 494 C CA . ASN A 1 64 ? -68.915 24.223 -34.096 1.00 34.32 ? 65 ASN A CA 1 ATOM 495 C C . ASN A 1 64 ? -67.659 25.124 -34.073 1.00 35.55 ? 65 ASN A C 1 ATOM 496 O O . ASN A 1 64 ? -67.182 25.571 -33.008 1.00 34.15 ? 65 ASN A O 1 ATOM 497 C CB . ASN A 1 64 ? -70.153 25.147 -34.263 1.00 35.64 ? 65 ASN A CB 1 ATOM 498 C CG . ASN A 1 64 ? -71.496 24.368 -34.415 1.00 41.35 ? 65 ASN A CG 1 ATOM 499 O OD1 . ASN A 1 64 ? -71.596 23.337 -35.076 1.00 39.76 ? 65 ASN A OD1 1 ATOM 500 N ND2 . ASN A 1 64 ? -72.535 24.929 -33.836 1.00 42.67 ? 65 ASN A ND2 1 ATOM 501 N N . ASN A 1 65 ? -67.189 25.432 -35.278 1.00 34.43 ? 66 ASN A N 1 ATOM 502 C CA . ASN A 1 65 ? -66.114 26.398 -35.481 1.00 34.69 ? 66 ASN A CA 1 ATOM 503 C C . ASN A 1 65 ? -66.739 27.734 -35.731 1.00 32.61 ? 66 ASN A C 1 ATOM 504 O O . ASN A 1 65 ? -67.885 27.798 -36.178 1.00 32.00 ? 66 ASN A O 1 ATOM 505 C CB . ASN A 1 65 ? -65.205 26.002 -36.643 1.00 34.46 ? 66 ASN A CB 1 ATOM 506 C CG . ASN A 1 65 ? -64.725 24.539 -36.561 1.00 36.64 ? 66 ASN A CG 1 ATOM 507 O OD1 . ASN A 1 65 ? -64.775 23.797 -37.551 1.00 38.31 ? 66 ASN A OD1 1 ATOM 508 N ND2 . ASN A 1 65 ? -64.268 24.131 -35.387 1.00 37.16 ? 66 ASN A ND2 1 ATOM 509 N N . CYS A 1 66 ? -66.004 28.809 -35.446 1.00 28.94 ? 67 CYS A N 1 ATOM 510 C CA . CYS A 1 66 ? -66.535 30.132 -35.705 1.00 29.29 ? 67 CYS A CA 1 ATOM 511 C C . CYS A 1 66 ? -66.594 30.410 -37.200 1.00 32.20 ? 67 CYS A C 1 ATOM 512 O O . CYS A 1 66 ? -65.895 29.759 -38.013 1.00 30.78 ? 67 CYS A O 1 ATOM 513 C CB . CYS A 1 66 ? -65.677 31.190 -34.957 1.00 35.23 ? 67 CYS A CB 1 ATOM 514 S SG . CYS A 1 66 ? -65.755 31.039 -33.134 1.00 37.72 ? 67 CYS A SG 1 ATOM 515 N N . GLN A 1 67 ? -67.445 31.355 -37.576 1.00 31.23 ? 68 GLN A N 1 ATOM 516 C CA . GLN A 1 67 ? -67.582 31.737 -38.943 1.00 29.84 ? 68 GLN A CA 1 ATOM 517 C C . GLN A 1 67 ? -66.272 32.343 -39.452 1.00 32.40 ? 68 GLN A C 1 ATOM 518 O O . GLN A 1 67 ? -65.756 33.220 -38.840 1.00 36.52 ? 68 GLN A O 1 ATOM 519 C CB . GLN A 1 67 ? -68.691 32.732 -39.144 1.00 29.52 ? 68 GLN A CB 1 ATOM 520 C CG . GLN A 1 67 ? -70.060 32.166 -38.996 1.00 32.81 ? 68 GLN A CG 1 ATOM 521 C CD . GLN A 1 67 ? -70.564 31.365 -40.219 1.00 34.13 ? 68 GLN A CD 1 ATOM 522 O OE1 . GLN A 1 67 ? -69.837 31.089 -41.143 1.00 35.84 ? 68 GLN A OE1 1 ATOM 523 N NE2 . GLN A 1 67 ? -71.789 30.906 -40.140 1.00 33.60 ? 68 GLN A NE2 1 ATOM 524 N N . GLN A 1 68 ? -65.793 31.880 -40.607 1.00 32.76 ? 69 GLN A N 1 ATOM 525 C CA . GLN A 1 68 ? -64.492 32.257 -41.135 1.00 35.50 ? 69 GLN A CA 1 ATOM 526 C C . GLN A 1 68 ? -64.320 31.978 -42.645 1.00 35.99 ? 69 GLN A C 1 ATOM 527 O O . GLN A 1 68 ? -64.882 31.019 -43.217 1.00 27.67 ? 69 GLN A O 1 ATOM 528 C CB . GLN A 1 68 ? -63.356 31.533 -40.378 1.00 32.03 ? 69 GLN A CB 1 ATOM 529 C CG . GLN A 1 68 ? -63.417 30.026 -40.412 1.00 29.11 ? 69 GLN A CG 1 ATOM 530 C CD . GLN A 1 68 ? -62.408 29.349 -39.458 1.00 33.34 ? 69 GLN A CD 1 ATOM 531 O OE1 . GLN A 1 68 ? -61.271 28.988 -39.852 1.00 29.10 ? 69 GLN A OE1 1 ATOM 532 N NE2 . GLN A 1 68 ? -62.850 29.141 -38.187 1.00 33.03 ? 69 GLN A NE2 1 ATOM 533 N N . TYR A 1 69 ? -63.498 32.827 -43.260 1.00 35.64 ? 70 TYR A N 1 ATOM 534 C CA . TYR A 1 69 ? -62.940 32.536 -44.569 1.00 33.26 ? 70 TYR A CA 1 ATOM 535 C C . TYR A 1 69 ? -62.437 31.121 -44.578 1.00 34.14 ? 70 TYR A C 1 ATOM 536 O O . TYR A 1 69 ? -61.777 30.691 -43.612 1.00 34.61 ? 70 TYR A O 1 ATOM 537 C CB . TYR A 1 69 ? -61.767 33.442 -44.850 1.00 35.69 ? 70 TYR A CB 1 ATOM 538 C CG . TYR A 1 69 ? -61.118 33.189 -46.175 1.00 34.37 ? 70 TYR A CG 1 ATOM 539 C CD1 . TYR A 1 69 ? -61.685 33.685 -47.367 1.00 34.48 ? 70 TYR A CD1 1 ATOM 540 C CD2 . TYR A 1 69 ? -59.920 32.506 -46.245 1.00 33.27 ? 70 TYR A CD2 1 ATOM 541 C CE1 . TYR A 1 69 ? -61.073 33.468 -48.601 1.00 33.66 ? 70 TYR A CE1 1 ATOM 542 C CE2 . TYR A 1 69 ? -59.294 32.265 -47.461 1.00 36.13 ? 70 TYR A CE2 1 ATOM 543 C CZ . TYR A 1 69 ? -59.862 32.742 -48.632 1.00 38.44 ? 70 TYR A CZ 1 ATOM 544 O OH . TYR A 1 69 ? -59.197 32.482 -49.799 1.00 36.63 ? 70 TYR A OH 1 ATOM 545 N N . VAL A 1 70 ? -62.744 30.408 -45.669 1.00 32.48 ? 71 VAL A N 1 ATOM 546 C CA . VAL A 1 70 ? -62.291 29.023 -45.897 1.00 30.35 ? 71 VAL A CA 1 ATOM 547 C C . VAL A 1 70 ? -61.351 28.942 -47.125 1.00 33.60 ? 71 VAL A C 1 ATOM 548 O O . VAL A 1 70 ? -61.698 29.416 -48.237 1.00 37.40 ? 71 VAL A O 1 ATOM 549 C CB . VAL A 1 70 ? -63.491 28.125 -46.081 1.00 30.89 ? 71 VAL A CB 1 ATOM 550 C CG1 . VAL A 1 70 ? -63.079 26.718 -46.435 1.00 32.19 ? 71 VAL A CG1 1 ATOM 551 C CG2 . VAL A 1 70 ? -64.327 28.098 -44.783 1.00 37.95 ? 71 VAL A CG2 1 ATOM 552 N N . ASP A 1 71 ? -60.150 28.396 -46.913 1.00 32.06 ? 72 ASP A N 1 ATOM 553 C CA . ASP A 1 71 ? -59.108 28.343 -47.935 1.00 31.35 ? 72 ASP A CA 1 ATOM 554 C C . ASP A 1 71 ? -59.534 27.253 -48.970 1.00 34.06 ? 72 ASP A C 1 ATOM 555 O O . ASP A 1 71 ? -59.625 26.098 -48.623 1.00 34.72 ? 72 ASP A O 1 ATOM 556 C CB . ASP A 1 71 ? -57.800 27.942 -47.293 1.00 31.68 ? 72 ASP A CB 1 ATOM 557 C CG . ASP A 1 71 ? -56.619 27.819 -48.305 1.00 34.93 ? 72 ASP A CG 1 ATOM 558 O OD1 . ASP A 1 71 ? -56.797 28.082 -49.483 1.00 37.77 ? 72 ASP A OD1 1 ATOM 559 O OD2 . ASP A 1 71 ? -55.495 27.512 -47.894 1.00 33.37 ? 72 ASP A OD2 1 ATOM 560 N N . GLU A 1 72 ? -59.790 27.643 -50.216 1.00 31.90 ? 73 GLU A N 1 ATOM 561 C CA . GLU A 1 72 ? -60.094 26.705 -51.300 1.00 35.90 ? 73 GLU A CA 1 ATOM 562 C C . GLU A 1 72 ? -59.026 26.839 -52.404 1.00 37.75 ? 73 GLU A C 1 ATOM 563 O O . GLU A 1 72 ? -59.264 26.597 -53.593 1.00 37.77 ? 73 GLU A O 1 ATOM 564 C CB . GLU A 1 72 ? -61.454 27.042 -51.858 1.00 35.27 ? 73 GLU A CB 1 ATOM 565 C CG . GLU A 1 72 ? -62.610 26.529 -51.058 1.00 44.10 ? 73 GLU A CG 1 ATOM 566 C CD . GLU A 1 72 ? -63.851 27.401 -51.280 1.00 56.31 ? 73 GLU A CD 1 ATOM 567 O OE1 . GLU A 1 72 ? -64.273 27.652 -52.458 1.00 50.22 ? 73 GLU A OE1 1 ATOM 568 O OE2 . GLU A 1 72 ? -64.389 27.863 -50.244 1.00 74.14 ? 73 GLU A OE2 1 ATOM 569 N N . GLN A 1 73 ? -57.847 27.280 -52.021 1.00 38.15 ? 74 GLN A N 1 ATOM 570 C CA . GLN A 1 73 ? -56.844 27.564 -53.010 1.00 41.78 ? 74 GLN A CA 1 ATOM 571 C C . GLN A 1 73 ? -56.352 26.233 -53.614 1.00 38.11 ? 74 GLN A C 1 ATOM 572 O O . GLN A 1 73 ? -55.951 26.199 -54.723 1.00 41.77 ? 74 GLN A O 1 ATOM 573 C CB . GLN A 1 73 ? -55.781 28.443 -52.366 1.00 39.43 ? 74 GLN A CB 1 ATOM 574 C CG . GLN A 1 73 ? -54.669 28.991 -53.228 1.00 50.99 ? 74 GLN A CG 1 ATOM 575 C CD . GLN A 1 73 ? -55.133 29.556 -54.554 1.00 54.57 ? 74 GLN A CD 1 ATOM 576 O OE1 . GLN A 1 73 ? -55.952 30.465 -54.605 1.00 53.21 ? 74 GLN A OE1 1 ATOM 577 N NE2 . GLN A 1 73 ? -54.575 29.037 -55.629 1.00 56.11 ? 74 GLN A NE2 1 ATOM 578 N N . PHE A 1 74 ? -56.460 25.129 -52.877 1.00 39.68 ? 75 PHE A N 1 ATOM 579 C CA . PHE A 1 74 ? -56.025 23.799 -53.332 1.00 35.64 ? 75 PHE A CA 1 ATOM 580 C C . PHE A 1 74 ? -56.990 22.695 -52.882 1.00 36.31 ? 75 PHE A C 1 ATOM 581 O O . PHE A 1 74 ? -56.702 21.912 -51.984 1.00 34.30 ? 75 PHE A O 1 ATOM 582 C CB . PHE A 1 74 ? -54.638 23.490 -52.797 1.00 32.63 ? 75 PHE A CB 1 ATOM 583 C CG . PHE A 1 74 ? -53.615 24.524 -53.147 1.00 33.86 ? 75 PHE A CG 1 ATOM 584 C CD1 . PHE A 1 74 ? -53.108 24.598 -54.460 1.00 30.76 ? 75 PHE A CD1 1 ATOM 585 C CD2 . PHE A 1 74 ? -53.105 25.404 -52.171 1.00 32.22 ? 75 PHE A CD2 1 ATOM 586 C CE1 . PHE A 1 74 ? -52.156 25.541 -54.785 1.00 30.00 ? 75 PHE A CE1 1 ATOM 587 C CE2 . PHE A 1 74 ? -52.123 26.339 -52.506 1.00 34.41 ? 75 PHE A CE2 1 ATOM 588 C CZ . PHE A 1 74 ? -51.658 26.406 -53.831 1.00 33.05 ? 75 PHE A CZ 1 ATOM 589 N N . PRO A 1 75 ? -58.150 22.635 -53.515 1.00 40.37 ? 76 PRO A N 1 ATOM 590 C CA . PRO A 1 75 ? -59.183 21.665 -53.198 1.00 40.43 ? 76 PRO A CA 1 ATOM 591 C C . PRO A 1 75 ? -58.703 20.258 -53.139 1.00 42.41 ? 76 PRO A C 1 ATOM 592 O O . PRO A 1 75 ? -57.949 19.793 -54.045 1.00 43.92 ? 76 PRO A O 1 ATOM 593 C CB . PRO A 1 75 ? -60.182 21.858 -54.317 1.00 35.21 ? 76 PRO A CB 1 ATOM 594 C CG . PRO A 1 75 ? -60.150 23.310 -54.521 1.00 37.66 ? 76 PRO A CG 1 ATOM 595 C CD . PRO A 1 75 ? -58.675 23.649 -54.442 1.00 44.78 ? 76 PRO A CD 1 ATOM 596 N N . GLY A 1 76 ? -59.108 19.615 -52.028 1.00 46.66 ? 77 GLY A N 1 ATOM 597 C CA . GLY A 1 76 ? -58.691 18.243 -51.659 1.00 44.75 ? 77 GLY A CA 1 ATOM 598 C C . GLY A 1 76 ? -57.255 18.047 -51.199 1.00 43.59 ? 77 GLY A C 1 ATOM 599 O O . GLY A 1 76 ? -56.841 16.925 -50.881 1.00 51.57 ? 77 GLY A O 1 ATOM 600 N N . PHE A 1 77 ? -56.467 19.120 -51.154 1.00 35.15 ? 78 PHE A N 1 ATOM 601 C CA . PHE A 1 77 ? -55.084 18.981 -50.798 1.00 31.75 ? 78 PHE A CA 1 ATOM 602 C C . PHE A 1 77 ? -54.946 19.013 -49.277 1.00 31.95 ? 78 PHE A C 1 ATOM 603 O O . PHE A 1 77 ? -55.435 19.897 -48.604 1.00 32.07 ? 78 PHE A O 1 ATOM 604 C CB . PHE A 1 77 ? -54.310 20.094 -51.441 1.00 31.30 ? 78 PHE A CB 1 ATOM 605 C CG . PHE A 1 77 ? -52.855 20.076 -51.117 1.00 33.10 ? 78 PHE A CG 1 ATOM 606 C CD1 . PHE A 1 77 ? -52.044 19.009 -51.497 1.00 32.78 ? 78 PHE A CD1 1 ATOM 607 C CD2 . PHE A 1 77 ? -52.286 21.153 -50.446 1.00 30.35 ? 78 PHE A CD2 1 ATOM 608 C CE1 . PHE A 1 77 ? -50.686 19.018 -51.204 1.00 33.17 ? 78 PHE A CE1 1 ATOM 609 C CE2 . PHE A 1 77 ? -50.944 21.191 -50.195 1.00 29.26 ? 78 PHE A CE2 1 ATOM 610 C CZ . PHE A 1 77 ? -50.144 20.107 -50.535 1.00 33.15 ? 78 PHE A CZ 1 ATOM 611 N N . SER A 1 78 ? -54.255 18.073 -48.707 1.00 32.78 ? 79 SER A N 1 ATOM 612 C CA . SER A 1 78 ? -54.360 17.979 -47.241 1.00 37.75 ? 79 SER A CA 1 ATOM 613 C C . SER A 1 78 ? -53.520 19.110 -46.600 1.00 38.44 ? 79 SER A C 1 ATOM 614 O O . SER A 1 78 ? -53.797 19.558 -45.475 1.00 33.38 ? 79 SER A O 1 ATOM 615 C CB . SER A 1 78 ? -53.898 16.616 -46.762 1.00 32.86 ? 79 SER A CB 1 ATOM 616 O OG . SER A 1 78 ? -52.502 16.549 -47.038 1.00 37.00 ? 79 SER A OG 1 ATOM 617 N N . GLY A 1 79 ? -52.513 19.591 -47.335 1.00 34.75 ? 80 GLY A N 1 ATOM 618 C CA . GLY A 1 79 ? -51.598 20.583 -46.775 1.00 32.91 ? 80 GLY A CA 1 ATOM 619 C C . GLY A 1 79 ? -52.288 21.865 -46.311 1.00 34.27 ? 80 GLY A C 1 ATOM 620 O O . GLY A 1 79 ? -51.848 22.479 -45.321 1.00 32.32 ? 80 GLY A O 1 ATOM 621 N N . SER A 1 80 ? -53.312 22.280 -47.068 1.00 30.36 ? 81 SER A N 1 ATOM 622 C CA . SER A 1 80 ? -54.059 23.475 -46.842 1.00 32.03 ? 81 SER A CA 1 ATOM 623 C C . SER A 1 80 ? -55.327 23.147 -46.079 1.00 35.25 ? 81 SER A C 1 ATOM 624 O O . SER A 1 80 ? -55.735 23.918 -45.196 1.00 35.36 ? 81 SER A O 1 ATOM 625 C CB . SER A 1 80 ? -54.456 24.202 -48.174 1.00 33.57 ? 81 SER A CB 1 ATOM 626 O OG . SER A 1 80 ? -55.151 23.386 -49.142 1.00 31.70 ? 81 SER A OG 1 ATOM 627 N N . GLU A 1 81 ? -55.961 22.036 -46.429 1.00 33.80 ? 82 GLU A N 1 ATOM 628 C CA . GLU A 1 81 ? -57.233 21.633 -45.798 1.00 36.68 ? 82 GLU A CA 1 ATOM 629 C C . GLU A 1 81 ? -57.120 21.183 -44.360 1.00 33.60 ? 82 GLU A C 1 ATOM 630 O O . GLU A 1 81 ? -58.081 21.261 -43.641 1.00 28.68 ? 82 GLU A O 1 ATOM 631 C CB . GLU A 1 81 ? -58.017 20.605 -46.655 1.00 41.16 ? 82 GLU A CB 1 ATOM 632 C CG . GLU A 1 81 ? -59.033 21.352 -47.520 1.00 47.07 ? 82 GLU A CG 1 ATOM 633 C CD . GLU A 1 81 ? -59.485 20.637 -48.751 1.00 52.71 ? 82 GLU A CD 1 ATOM 634 O OE1 . GLU A 1 81 ? -59.411 19.403 -48.778 1.00 62.19 ? 82 GLU A OE1 1 ATOM 635 O OE2 . GLU A 1 81 ? -59.965 21.324 -49.688 1.00 55.71 ? 82 GLU A OE2 1 ATOM 636 N N . MET A 1 82 ? -55.931 20.814 -43.905 1.00 30.05 ? 83 MET A N 1 ATOM 637 C CA . MET A 1 82 ? -55.780 20.508 -42.491 1.00 29.69 ? 83 MET A CA 1 ATOM 638 C C . MET A 1 82 ? -55.975 21.728 -41.557 1.00 34.47 ? 83 MET A C 1 ATOM 639 O O . MET A 1 82 ? -56.033 21.523 -40.344 1.00 32.81 ? 83 MET A O 1 ATOM 640 C CB . MET A 1 82 ? -54.423 19.902 -42.209 1.00 30.69 ? 83 MET A CB 1 ATOM 641 C CG . MET A 1 82 ? -53.307 20.878 -42.438 1.00 35.94 ? 83 MET A CG 1 ATOM 642 S SD . MET A 1 82 ? -51.764 20.105 -42.064 1.00 41.49 ? 83 MET A SD 1 ATOM 643 C CE . MET A 1 82 ? -51.598 20.388 -40.312 1.00 45.51 ? 83 MET A CE 1 ATOM 644 N N . TRP A 1 83 ? -56.052 22.950 -42.126 1.00 29.64 ? 84 TRP A N 1 ATOM 645 C CA . TRP A 1 83 ? -56.167 24.190 -41.396 1.00 31.99 ? 84 TRP A CA 1 ATOM 646 C C . TRP A 1 83 ? -57.580 24.712 -41.427 1.00 32.26 ? 84 TRP A C 1 ATOM 647 O O . TRP A 1 83 ? -57.929 25.636 -40.688 1.00 32.59 ? 84 TRP A O 1 ATOM 648 C CB . TRP A 1 83 ? -55.169 25.259 -41.949 1.00 30.20 ? 84 TRP A CB 1 ATOM 649 C CG . TRP A 1 83 ? -53.761 24.788 -41.879 1.00 31.95 ? 84 TRP A CG 1 ATOM 650 C CD1 . TRP A 1 83 ? -52.964 24.387 -42.934 1.00 37.47 ? 84 TRP A CD1 1 ATOM 651 C CD2 . TRP A 1 83 ? -52.975 24.577 -40.712 1.00 33.94 ? 84 TRP A CD2 1 ATOM 652 N NE1 . TRP A 1 83 ? -51.730 23.991 -42.490 1.00 34.49 ? 84 TRP A NE1 1 ATOM 653 C CE2 . TRP A 1 83 ? -51.713 24.093 -41.126 1.00 36.18 ? 84 TRP A CE2 1 ATOM 654 C CE3 . TRP A 1 83 ? -53.205 24.736 -39.360 1.00 33.80 ? 84 TRP A CE3 1 ATOM 655 C CZ2 . TRP A 1 83 ? -50.711 23.797 -40.230 1.00 36.06 ? 84 TRP A CZ2 1 ATOM 656 C CZ3 . TRP A 1 83 ? -52.198 24.433 -38.478 1.00 33.47 ? 84 TRP A CZ3 1 ATOM 657 C CH2 . TRP A 1 83 ? -50.982 23.956 -38.913 1.00 34.99 ? 84 TRP A CH2 1 ATOM 658 N N . ASN A 1 84 ? -58.407 24.148 -42.290 1.00 31.56 ? 85 ASN A N 1 ATOM 659 C CA . ASN A 1 84 ? -59.766 24.681 -42.436 1.00 31.30 ? 85 ASN A CA 1 ATOM 660 C C . ASN A 1 84 ? -60.661 24.098 -41.364 1.00 29.96 ? 85 ASN A C 1 ATOM 661 O O . ASN A 1 84 ? -60.377 23.020 -40.794 1.00 28.73 ? 85 ASN A O 1 ATOM 662 C CB . ASN A 1 84 ? -60.365 24.279 -43.809 1.00 35.58 ? 85 ASN A CB 1 ATOM 663 C CG . ASN A 1 84 ? -59.907 25.177 -44.981 1.00 41.32 ? 85 ASN A CG 1 ATOM 664 O OD1 . ASN A 1 84 ? -59.593 26.397 -44.845 1.00 37.40 ? 85 ASN A OD1 1 ATOM 665 N ND2 . ASN A 1 84 ? -59.854 24.550 -46.154 1.00 34.79 ? 85 ASN A ND2 1 ATOM 666 N N . PRO A 1 85 ? -61.807 24.737 -41.154 1.00 26.61 ? 86 PRO A N 1 ATOM 667 C CA . PRO A 1 85 ? -62.811 24.193 -40.255 1.00 26.38 ? 86 PRO A CA 1 ATOM 668 C C . PRO A 1 85 ? -63.188 22.777 -40.629 1.00 28.52 ? 86 PRO A C 1 ATOM 669 O O . PRO A 1 85 ? -63.517 22.541 -41.786 1.00 32.10 ? 86 PRO A O 1 ATOM 670 C CB . PRO A 1 85 ? -64.021 25.081 -40.454 1.00 24.65 ? 86 PRO A CB 1 ATOM 671 C CG . PRO A 1 85 ? -63.555 26.288 -41.216 1.00 26.40 ? 86 PRO A CG 1 ATOM 672 C CD . PRO A 1 85 ? -62.222 25.990 -41.811 1.00 26.27 ? 86 PRO A CD 1 ATOM 673 N N . ASN A 1 86 ? -63.125 21.846 -39.667 1.00 28.69 ? 87 ASN A N 1 ATOM 674 C CA . ASN A 1 86 ? -63.656 20.483 -39.865 1.00 27.66 ? 87 ASN A CA 1 ATOM 675 C C . ASN A 1 86 ? -65.015 20.298 -39.171 1.00 30.97 ? 87 ASN A C 1 ATOM 676 O O . ASN A 1 86 ? -65.519 19.199 -39.069 1.00 34.61 ? 87 ASN A O 1 ATOM 677 C CB . ASN A 1 86 ? -62.660 19.438 -39.372 1.00 27.61 ? 87 ASN A CB 1 ATOM 678 C CG . ASN A 1 86 ? -62.277 19.637 -37.866 1.00 32.56 ? 87 ASN A CG 1 ATOM 679 O OD1 . ASN A 1 86 ? -62.700 20.611 -37.192 1.00 36.49 ? 87 ASN A OD1 1 ATOM 680 N ND2 . ASN A 1 86 ? -61.512 18.735 -37.363 1.00 27.70 ? 87 ASN A ND2 1 ATOM 681 N N . ARG A 1 87 ? -65.626 21.347 -38.679 1.00 32.59 ? 88 ARG A N 1 ATOM 682 C CA . ARG A 1 87 ? -66.987 21.200 -38.173 1.00 36.23 ? 88 ARG A CA 1 ATOM 683 C C . ARG A 1 87 ? -67.862 22.184 -38.869 1.00 35.98 ? 88 ARG A C 1 ATOM 684 O O . ARG A 1 87 ? -67.381 23.041 -39.552 1.00 37.43 ? 88 ARG A O 1 ATOM 685 C CB . ARG A 1 87 ? -67.007 21.418 -36.616 1.00 36.73 ? 88 ARG A CB 1 ATOM 686 C CG . ARG A 1 87 ? -66.428 20.208 -35.828 1.00 40.06 ? 88 ARG A CG 1 ATOM 687 C CD . ARG A 1 87 ? -67.472 19.070 -35.839 1.00 45.48 ? 88 ARG A CD 1 ATOM 688 N NE . ARG A 1 87 ? -67.088 17.782 -35.272 1.00 53.31 ? 88 ARG A NE 1 ATOM 689 C CZ . ARG A 1 87 ? -66.083 17.002 -35.719 1.00 63.01 ? 88 ARG A CZ 1 ATOM 690 N NH1 . ARG A 1 87 ? -65.309 17.342 -36.765 1.00 68.78 ? 88 ARG A NH1 1 ATOM 691 N NH2 . ARG A 1 87 ? -65.806 15.862 -35.101 1.00 63.57 ? 88 ARG A NH2 1 ATOM 692 N N . GLU A 1 88 ? -69.157 22.132 -38.653 1.00 39.77 ? 89 GLU A N 1 ATOM 693 C CA . GLU A 1 88 ? -69.991 23.144 -39.232 1.00 43.64 ? 89 GLU A CA 1 ATOM 694 C C . GLU A 1 88 ? -69.579 24.494 -38.630 1.00 39.49 ? 89 GLU A C 1 ATOM 695 O O . GLU A 1 88 ? -69.233 24.542 -37.486 1.00 32.17 ? 89 GLU A O 1 ATOM 696 C CB . GLU A 1 88 ? -71.478 22.866 -39.013 1.00 52.77 ? 89 GLU A CB 1 ATOM 697 C CG . GLU A 1 88 ? -72.369 23.674 -39.953 1.00 67.79 ? 89 GLU A CG 1 ATOM 698 C CD . GLU A 1 88 ? -73.823 23.801 -39.489 1.00 76.02 ? 89 GLU A CD 1 ATOM 699 O OE1 . GLU A 1 88 ? -74.676 23.173 -40.135 1.00 84.61 ? 89 GLU A OE1 1 ATOM 700 O OE2 . GLU A 1 88 ? -74.125 24.533 -38.505 1.00 78.30 ? 89 GLU A OE2 1 ATOM 701 N N . MET A 1 89 ? -69.590 25.565 -39.423 1.00 35.27 ? 90 MET A N 1 ATOM 702 C CA . MET A 1 89 ? -69.351 26.893 -38.916 1.00 33.55 ? 90 MET A CA 1 ATOM 703 C C . MET A 1 89 ? -70.633 27.453 -38.337 1.00 33.12 ? 90 MET A C 1 ATOM 704 O O . MET A 1 89 ? -71.738 27.210 -38.879 1.00 34.39 ? 90 MET A O 1 ATOM 705 C CB . MET A 1 89 ? -68.783 27.823 -40.017 1.00 31.21 ? 90 MET A CB 1 ATOM 706 C CG . MET A 1 89 ? -67.350 27.443 -40.435 1.00 33.34 ? 90 MET A CG 1 ATOM 707 S SD . MET A 1 89 ? -66.594 28.681 -41.510 1.00 35.20 ? 90 MET A SD 1 ATOM 708 C CE . MET A 1 89 ? -67.679 28.563 -42.947 1.00 39.65 ? 90 MET A CE 1 ATOM 709 N N . SER A 1 90 ? -70.486 28.236 -37.266 1.00 32.18 ? 91 SER A N 1 ATOM 710 C CA . SER A 1 90 ? -71.618 28.985 -36.662 1.00 31.32 ? 91 SER A CA 1 ATOM 711 C C . SER A 1 90 ? -71.117 30.182 -35.871 1.00 30.14 ? 91 SER A C 1 ATOM 712 O O . SER A 1 90 ? -70.063 30.120 -35.264 1.00 28.45 ? 91 SER A O 1 ATOM 713 C CB . SER A 1 90 ? -72.384 28.057 -35.699 1.00 29.94 ? 91 SER A CB 1 ATOM 714 O OG . SER A 1 90 ? -73.493 28.691 -35.094 1.00 30.38 ? 91 SER A OG 1 ATOM 715 N N . GLU A 1 91 ? -71.917 31.242 -35.809 1.00 34.88 ? 92 GLU A N 1 ATOM 716 C CA . GLU A 1 91 ? -71.686 32.328 -34.834 1.00 32.66 ? 92 GLU A CA 1 ATOM 717 C C . GLU A 1 91 ? -71.713 31.837 -33.377 1.00 32.59 ? 92 GLU A C 1 ATOM 718 O O . GLU A 1 91 ? -71.122 32.452 -32.481 1.00 33.62 ? 92 GLU A O 1 ATOM 719 C CB . GLU A 1 91 ? -72.692 33.455 -35.042 1.00 30.21 ? 92 GLU A CB 1 ATOM 720 C CG . GLU A 1 91 ? -72.285 34.309 -36.219 1.00 30.34 ? 92 GLU A CG 1 ATOM 721 C CD . GLU A 1 91 ? -73.061 35.570 -36.370 1.00 33.31 ? 92 GLU A CD 1 ATOM 722 O OE1 . GLU A 1 91 ? -72.557 36.621 -35.904 1.00 33.90 ? 92 GLU A OE1 1 ATOM 723 O OE2 . GLU A 1 91 ? -74.167 35.502 -36.996 1.00 37.13 ? 92 GLU A OE2 1 ATOM 724 N N . ASP A 1 92 ? -72.395 30.725 -33.152 1.00 32.99 ? 93 ASP A N 1 ATOM 725 C CA . ASP A 1 92 ? -72.461 30.101 -31.844 1.00 35.89 ? 93 ASP A CA 1 ATOM 726 C C . ASP A 1 92 ? -71.331 29.145 -31.750 1.00 31.62 ? 93 ASP A C 1 ATOM 727 O O . ASP A 1 92 ? -71.460 27.954 -32.099 1.00 36.23 ? 93 ASP A O 1 ATOM 728 C CB . ASP A 1 92 ? -73.800 29.377 -31.690 1.00 38.53 ? 93 ASP A CB 1 ATOM 729 C CG . ASP A 1 92 ? -73.945 28.646 -30.354 1.00 36.21 ? 93 ASP A CG 1 ATOM 730 O OD1 . ASP A 1 92 ? -73.033 28.546 -29.481 1.00 36.03 ? 93 ASP A OD1 1 ATOM 731 O OD2 . ASP A 1 92 ? -75.039 28.129 -30.227 1.00 37.93 ? 93 ASP A OD2 1 ATOM 732 N N . CYS A 1 93 ? -70.208 29.668 -31.277 1.00 29.53 ? 94 CYS A N 1 ATOM 733 C CA . CYS A 1 93 ? -68.954 28.938 -31.342 1.00 30.51 ? 94 CYS A CA 1 ATOM 734 C C . CYS A 1 93 ? -68.055 29.123 -30.183 1.00 31.55 ? 94 CYS A C 1 ATOM 735 O O . CYS A 1 93 ? -66.871 28.674 -30.254 1.00 29.25 ? 94 CYS A O 1 ATOM 736 C CB . CYS A 1 93 ? -68.145 29.364 -32.590 1.00 31.42 ? 94 CYS A CB 1 ATOM 737 S SG . CYS A 1 93 ? -67.759 31.117 -32.703 1.00 33.01 ? 94 CYS A SG 1 ATOM 738 N N . LEU A 1 94 ? -68.554 29.755 -29.115 1.00 29.99 ? 95 LEU A N 1 ATOM 739 C CA . LEU A 1 94 ? -67.654 29.971 -27.977 1.00 29.45 ? 95 LEU A CA 1 ATOM 740 C C . LEU A 1 94 ? -67.680 28.817 -26.980 1.00 29.96 ? 95 LEU A C 1 ATOM 741 O O . LEU A 1 94 ? -68.453 28.843 -26.021 1.00 28.64 ? 95 LEU A O 1 ATOM 742 C CB . LEU A 1 94 ? -67.962 31.277 -27.350 1.00 31.28 ? 95 LEU A CB 1 ATOM 743 C CG . LEU A 1 94 ? -67.779 32.449 -28.304 1.00 32.23 ? 95 LEU A CG 1 ATOM 744 C CD1 . LEU A 1 94 ? -68.049 33.748 -27.575 1.00 33.39 ? 95 LEU A CD1 1 ATOM 745 C CD2 . LEU A 1 94 ? -66.372 32.497 -28.924 1.00 32.75 ? 95 LEU A CD2 1 ATOM 746 N N . TYR A 1 95 ? -66.794 27.838 -27.227 1.00 26.76 ? 96 TYR A N 1 ATOM 747 C CA . TYR A 1 95 ? -66.688 26.600 -26.485 1.00 25.12 ? 96 TYR A CA 1 ATOM 748 C C . TYR A 1 95 ? -65.241 26.286 -26.260 1.00 26.65 ? 96 TYR A C 1 ATOM 749 O O . TYR A 1 95 ? -64.353 26.809 -26.943 1.00 26.41 ? 96 TYR A O 1 ATOM 750 C CB . TYR A 1 95 ? -67.337 25.420 -27.277 1.00 29.36 ? 96 TYR A CB 1 ATOM 751 C CG . TYR A 1 95 ? -68.813 25.644 -27.538 1.00 29.27 ? 96 TYR A CG 1 ATOM 752 C CD1 . TYR A 1 95 ? -69.231 26.452 -28.560 1.00 29.90 ? 96 TYR A CD1 1 ATOM 753 C CD2 . TYR A 1 95 ? -69.767 25.118 -26.704 1.00 30.07 ? 96 TYR A CD2 1 ATOM 754 C CE1 . TYR A 1 95 ? -70.582 26.720 -28.772 1.00 30.03 ? 96 TYR A CE1 1 ATOM 755 C CE2 . TYR A 1 95 ? -71.118 25.372 -26.906 1.00 30.53 ? 96 TYR A CE2 1 ATOM 756 C CZ . TYR A 1 95 ? -71.505 26.172 -27.922 1.00 30.93 ? 96 TYR A CZ 1 ATOM 757 O OH . TYR A 1 95 ? -72.795 26.484 -28.049 1.00 30.04 ? 96 TYR A OH 1 ATOM 758 N N . LEU A 1 96 ? -64.977 25.421 -25.291 1.00 27.41 ? 97 LEU A N 1 ATOM 759 C CA . LEU A 1 96 ? -63.645 24.951 -25.086 1.00 27.00 ? 97 LEU A CA 1 ATOM 760 C C . LEU A 1 96 ? -63.657 23.435 -24.924 1.00 25.25 ? 97 LEU A C 1 ATOM 761 O O . LEU A 1 96 ? -64.722 22.859 -24.733 1.00 28.53 ? 97 LEU A O 1 ATOM 762 C CB . LEU A 1 96 ? -63.061 25.679 -23.893 1.00 30.25 ? 97 LEU A CB 1 ATOM 763 C CG . LEU A 1 96 ? -63.770 25.672 -22.519 1.00 33.78 ? 97 LEU A CG 1 ATOM 764 C CD1 . LEU A 1 96 ? -63.552 24.369 -21.771 1.00 30.52 ? 97 LEU A CD1 1 ATOM 765 C CD2 . LEU A 1 96 ? -63.173 26.812 -21.697 1.00 33.18 ? 97 LEU A CD2 1 ATOM 766 N N . ASN A 1 97 ? -62.474 22.833 -24.968 1.00 24.99 ? 98 ASN A N 1 ATOM 767 C CA . ASN A 1 97 ? -62.215 21.400 -24.936 1.00 26.76 ? 98 ASN A CA 1 ATOM 768 C C . ASN A 1 97 ? -61.142 21.076 -23.912 1.00 27.07 ? 98 ASN A C 1 ATOM 769 O O . ASN A 1 97 ? -60.179 21.815 -23.807 1.00 26.87 ? 98 ASN A O 1 ATOM 770 C CB . ASN A 1 97 ? -61.755 20.875 -26.326 1.00 28.23 ? 98 ASN A CB 1 ATOM 771 C CG . ASN A 1 97 ? -62.632 21.413 -27.459 1.00 29.26 ? 98 ASN A CG 1 ATOM 772 O OD1 . ASN A 1 97 ? -63.832 21.149 -27.526 1.00 32.49 ? 98 ASN A OD1 1 ATOM 773 N ND2 . ASN A 1 97 ? -62.054 22.253 -28.289 1.00 31.42 ? 98 ASN A ND2 1 ATOM 774 N N . ILE A 1 98 ? -61.308 19.953 -23.199 1.00 27.55 ? 99 ILE A N 1 ATOM 775 C CA . ILE A 1 98 ? -60.384 19.549 -22.113 1.00 32.80 ? 99 ILE A CA 1 ATOM 776 C C . ILE A 1 98 ? -60.071 18.077 -22.188 1.00 30.45 ? 99 ILE A C 1 ATOM 777 O O . ILE A 1 98 ? -60.966 17.275 -22.221 1.00 34.54 ? 99 ILE A O 1 ATOM 778 C CB . ILE A 1 98 ? -60.951 19.787 -20.674 1.00 31.58 ? 99 ILE A CB 1 ATOM 779 C CG1 . ILE A 1 98 ? -61.615 21.183 -20.563 1.00 36.81 ? 99 ILE A CG1 1 ATOM 780 C CG2 . ILE A 1 98 ? -59.788 19.743 -19.703 1.00 34.09 ? 99 ILE A CG2 1 ATOM 781 C CD1 . ILE A 1 98 ? -62.275 21.575 -19.228 1.00 38.06 ? 99 ILE A CD1 1 ATOM 782 N N . TRP A 1 99 ? -58.809 17.754 -22.199 1.00 29.49 ? 100 TRP A N 1 ATOM 783 C CA . TRP A 1 99 ? -58.342 16.400 -22.160 1.00 35.47 ? 100 TRP A CA 1 ATOM 784 C C . TRP A 1 99 ? -57.702 16.232 -20.789 1.00 38.12 ? 100 TRP A C 1 ATOM 785 O O . TRP A 1 99 ? -56.872 17.052 -20.403 1.00 37.17 ? 100 TRP A O 1 ATOM 786 C CB . TRP A 1 99 ? -57.309 16.087 -23.241 1.00 36.24 ? 100 TRP A CB 1 ATOM 787 C CG . TRP A 1 99 ? -57.930 15.998 -24.628 1.00 37.25 ? 100 TRP A CG 1 ATOM 788 C CD1 . TRP A 1 99 ? -58.361 14.880 -25.250 1.00 41.26 ? 100 TRP A CD1 1 ATOM 789 C CD2 . TRP A 1 99 ? -58.169 17.075 -25.548 1.00 36.52 ? 100 TRP A CD2 1 ATOM 790 N NE1 . TRP A 1 99 ? -58.909 15.181 -26.481 1.00 38.08 ? 100 TRP A NE1 1 ATOM 791 C CE2 . TRP A 1 99 ? -58.751 16.512 -26.712 1.00 36.54 ? 100 TRP A CE2 1 ATOM 792 C CE3 . TRP A 1 99 ? -57.930 18.451 -25.516 1.00 37.34 ? 100 TRP A CE3 1 ATOM 793 C CZ2 . TRP A 1 99 ? -59.107 17.278 -27.831 1.00 37.63 ? 100 TRP A CZ2 1 ATOM 794 C CZ3 . TRP A 1 99 ? -58.301 19.232 -26.669 1.00 37.23 ? 100 TRP A CZ3 1 ATOM 795 C CH2 . TRP A 1 99 ? -58.869 18.631 -27.788 1.00 32.66 ? 100 TRP A CH2 1 ATOM 796 N N . VAL A 1 100 ? -58.165 15.197 -20.074 1.00 34.24 ? 101 VAL A N 1 ATOM 797 C CA . VAL A 1 100 ? -57.837 14.952 -18.666 1.00 37.85 ? 101 VAL A CA 1 ATOM 798 C C . VAL A 1 100 ? -57.328 13.499 -18.528 1.00 33.40 ? 101 VAL A C 1 ATOM 799 O O . VAL A 1 100 ? -58.052 12.558 -18.906 1.00 33.61 ? 101 VAL A O 1 ATOM 800 C CB . VAL A 1 100 ? -59.114 15.091 -17.797 1.00 37.39 ? 101 VAL A CB 1 ATOM 801 C CG1 . VAL A 1 100 ? -58.827 14.800 -16.332 1.00 36.98 ? 101 VAL A CG1 1 ATOM 802 C CG2 . VAL A 1 100 ? -59.783 16.451 -18.020 1.00 39.13 ? 101 VAL A CG2 1 ATOM 803 N N . PRO A 1 101 ? -56.114 13.327 -18.025 1.00 29.98 ? 102 PRO A N 1 ATOM 804 C CA . PRO A 1 101 ? -55.627 11.981 -17.734 1.00 33.64 ? 102 PRO A CA 1 ATOM 805 C C . PRO A 1 101 ? -56.598 11.087 -16.929 1.00 39.44 ? 102 PRO A C 1 ATOM 806 O O . PRO A 1 101 ? -57.536 11.583 -16.223 1.00 34.73 ? 102 PRO A O 1 ATOM 807 C CB . PRO A 1 101 ? -54.376 12.214 -16.916 1.00 29.82 ? 102 PRO A CB 1 ATOM 808 C CG . PRO A 1 101 ? -53.903 13.602 -17.349 1.00 30.77 ? 102 PRO A CG 1 ATOM 809 C CD . PRO A 1 101 ? -55.175 14.371 -17.553 1.00 30.88 ? 102 PRO A CD 1 ATOM 810 N N . SER A 1 102 ? -56.403 9.779 -17.103 1.00 41.50 ? 103 SER A N 1 ATOM 811 C CA . SER A 1 102 ? -57.202 8.750 -16.431 1.00 49.09 ? 103 SER A CA 1 ATOM 812 C C . SER A 1 102 ? -56.235 7.852 -15.745 1.00 47.11 ? 103 SER A C 1 ATOM 813 O O . SER A 1 102 ? -55.382 7.269 -16.380 1.00 48.67 ? 103 SER A O 1 ATOM 814 C CB . SER A 1 102 ? -58.032 7.942 -17.402 1.00 52.01 ? 103 SER A CB 1 ATOM 815 O OG . SER A 1 102 ? -59.151 7.393 -16.747 1.00 54.10 ? 103 SER A OG 1 ATOM 816 N N . PRO A 1 103 ? -56.346 7.733 -14.436 1.00 53.67 ? 104 PRO A N 1 ATOM 817 C CA . PRO A 1 103 ? -57.412 8.337 -13.663 1.00 54.85 ? 104 PRO A CA 1 ATOM 818 C C . PRO A 1 103 ? -57.213 9.863 -13.494 1.00 44.16 ? 104 PRO A C 1 ATOM 819 O O . PRO A 1 103 ? -56.078 10.371 -13.569 1.00 32.27 ? 104 PRO A O 1 ATOM 820 C CB . PRO A 1 103 ? -57.305 7.609 -12.295 1.00 54.18 ? 104 PRO A CB 1 ATOM 821 C CG . PRO A 1 103 ? -55.843 7.325 -12.173 1.00 57.78 ? 104 PRO A CG 1 ATOM 822 C CD . PRO A 1 103 ? -55.348 7.058 -13.581 1.00 57.38 ? 104 PRO A CD 1 ATOM 823 N N . ARG A 1 104 ? -58.325 10.551 -13.230 1.00 41.32 ? 105 ARG A N 1 ATOM 824 C CA . ARG A 1 104 ? -58.329 12.011 -12.985 1.00 42.63 ? 105 ARG A CA 1 ATOM 825 C C . ARG A 1 104 ? -57.302 12.428 -11.968 1.00 44.25 ? 105 ARG A C 1 ATOM 826 O O . ARG A 1 104 ? -57.267 11.889 -10.875 1.00 48.21 ? 105 ARG A O 1 ATOM 827 C CB . ARG A 1 104 ? -59.685 12.464 -12.524 1.00 37.11 ? 105 ARG A CB 1 ATOM 828 C CG . ARG A 1 104 ? -59.832 13.955 -12.586 1.00 38.14 ? 105 ARG A CG 1 ATOM 829 C CD . ARG A 1 104 ? -61.148 14.382 -11.981 1.00 33.52 ? 105 ARG A CD 1 ATOM 830 N NE . ARG A 1 104 ? -62.278 13.811 -12.670 1.00 36.28 ? 105 ARG A NE 1 ATOM 831 C CZ . ARG A 1 104 ? -63.534 13.980 -12.282 1.00 36.60 ? 105 ARG A CZ 1 ATOM 832 N NH1 . ARG A 1 104 ? -63.758 14.631 -11.172 1.00 36.76 ? 105 ARG A NH1 1 ATOM 833 N NH2 . ARG A 1 104 ? -64.584 13.461 -12.944 1.00 34.89 ? 105 ARG A NH2 1 ATOM 834 N N . PRO A 1 105 ? -56.421 13.356 -12.340 1.00 43.88 ? 106 PRO A N 1 ATOM 835 C CA . PRO A 1 105 ? -55.455 13.899 -11.389 1.00 40.50 ? 106 PRO A CA 1 ATOM 836 C C . PRO A 1 105 ? -56.131 14.761 -10.312 1.00 35.77 ? 106 PRO A C 1 ATOM 837 O O . PRO A 1 105 ? -57.326 15.006 -10.373 1.00 42.63 ? 106 PRO A O 1 ATOM 838 C CB . PRO A 1 105 ? -54.532 14.740 -12.274 1.00 43.39 ? 106 PRO A CB 1 ATOM 839 C CG . PRO A 1 105 ? -55.324 15.074 -13.455 1.00 45.93 ? 106 PRO A CG 1 ATOM 840 C CD . PRO A 1 105 ? -56.350 14.009 -13.656 1.00 47.98 ? 106 PRO A CD 1 ATOM 841 N N . LYS A 1 106 ? -55.385 15.277 -9.361 1.00 42.14 ? 107 LYS A N 1 ATOM 842 C CA . LYS A 1 106 ? -56.028 16.149 -8.349 1.00 47.23 ? 107 LYS A CA 1 ATOM 843 C C . LYS A 1 106 ? -55.699 17.595 -8.560 1.00 44.59 ? 107 LYS A C 1 ATOM 844 O O . LYS A 1 106 ? -56.536 18.471 -8.355 1.00 45.00 ? 107 LYS A O 1 ATOM 845 C CB . LYS A 1 106 ? -55.626 15.737 -6.921 1.00 50.22 ? 107 LYS A CB 1 ATOM 846 C CG . LYS A 1 106 ? -55.777 14.236 -6.610 1.00 52.95 ? 107 LYS A CG 1 ATOM 847 C CD . LYS A 1 106 ? -57.225 13.742 -6.748 1.00 61.03 ? 107 LYS A CD 1 ATOM 848 C CE . LYS A 1 106 ? -57.268 12.198 -6.771 1.00 63.86 ? 107 LYS A CE 1 ATOM 849 N NZ . LYS A 1 106 ? -58.625 11.645 -6.510 1.00 63.64 ? 107 LYS A NZ 1 ATOM 850 N N . SER A 1 107 ? -54.446 17.853 -8.885 1.00 41.53 ? 108 SER A N 1 ATOM 851 C CA . SER A 1 107 ? -54.029 19.235 -9.022 1.00 48.75 ? 108 SER A CA 1 ATOM 852 C C . SER A 1 107 ? -52.854 19.303 -9.957 1.00 41.15 ? 108 SER A C 1 ATOM 853 O O . SER A 1 107 ? -51.745 19.516 -9.531 1.00 44.62 ? 108 SER A O 1 ATOM 854 C CB . SER A 1 107 ? -53.643 19.827 -7.682 1.00 45.26 ? 108 SER A CB 1 ATOM 855 O OG . SER A 1 107 ? -53.717 21.220 -7.771 1.00 50.54 ? 108 SER A OG 1 ATOM 856 N N . THR A 1 108 ? -53.106 19.086 -11.235 1.00 36.07 ? 109 THR A N 1 ATOM 857 C CA . THR A 1 108 ? -51.994 19.010 -12.157 1.00 36.21 ? 109 THR A CA 1 ATOM 858 C C . THR A 1 108 ? -51.809 20.278 -13.077 1.00 32.52 ? 109 THR A C 1 ATOM 859 O O . THR A 1 108 ? -52.728 21.122 -13.270 1.00 27.58 ? 109 THR A O 1 ATOM 860 C CB . THR A 1 108 ? -51.974 17.685 -12.922 1.00 33.79 ? 109 THR A CB 1 ATOM 861 O OG1 . THR A 1 108 ? -50.662 17.536 -13.488 1.00 45.32 ? 109 THR A OG1 1 ATOM 862 C CG2 . THR A 1 108 ? -52.972 17.682 -14.012 1.00 35.79 ? 109 THR A CG2 1 ATOM 863 N N . THR A 1 109 ? -50.597 20.386 -13.599 1.00 30.75 ? 110 THR A N 1 ATOM 864 C CA . THR A 1 109 ? -50.263 21.397 -14.587 1.00 31.24 ? 110 THR A CA 1 ATOM 865 C C . THR A 1 109 ? -51.295 21.445 -15.705 1.00 28.74 ? 110 THR A C 1 ATOM 866 O O . THR A 1 109 ? -51.779 20.424 -16.189 1.00 33.03 ? 110 THR A O 1 ATOM 867 C CB . THR A 1 109 ? -48.890 21.172 -15.182 1.00 34.72 ? 110 THR A CB 1 ATOM 868 O OG1 . THR A 1 109 ? -47.920 21.078 -14.143 1.00 35.32 ? 110 THR A OG1 1 ATOM 869 C CG2 . THR A 1 109 ? -48.539 22.330 -16.094 1.00 37.25 ? 110 THR A CG2 1 ATOM 870 N N . VAL A 1 110 ? -51.690 22.657 -16.043 1.00 28.97 ? 111 VAL A N 1 ATOM 871 C CA . VAL A 1 110 ? -52.726 22.930 -17.059 1.00 30.33 ? 111 VAL A CA 1 ATOM 872 C C . VAL A 1 110 ? -52.058 23.738 -18.243 1.00 30.18 ? 111 VAL A C 1 ATOM 873 O O . VAL A 1 110 ? -51.313 24.710 -18.007 1.00 28.95 ? 111 VAL A O 1 ATOM 874 C CB . VAL A 1 110 ? -53.826 23.782 -16.429 1.00 29.81 ? 111 VAL A CB 1 ATOM 875 C CG1 . VAL A 1 110 ? -54.947 24.103 -17.412 1.00 32.75 ? 111 VAL A CG1 1 ATOM 876 C CG2 . VAL A 1 110 ? -54.372 23.135 -15.157 1.00 29.25 ? 111 VAL A CG2 1 ATOM 877 N N . MET A 1 111 ? -52.342 23.334 -19.481 1.00 29.18 ? 112 MET A N 1 ATOM 878 C CA . MET A 1 111 ? -51.876 24.045 -20.683 1.00 27.02 ? 112 MET A CA 1 ATOM 879 C C . MET A 1 111 ? -53.089 24.438 -21.484 1.00 29.10 ? 112 MET A C 1 ATOM 880 O O . MET A 1 111 ? -54.013 23.623 -21.650 1.00 31.91 ? 112 MET A O 1 ATOM 881 C CB . MET A 1 111 ? -50.962 23.169 -21.476 1.00 28.43 ? 112 MET A CB 1 ATOM 882 C CG . MET A 1 111 ? -49.634 22.931 -20.770 1.00 27.11 ? 112 MET A CG 1 ATOM 883 S SD . MET A 1 111 ? -48.452 21.880 -21.649 1.00 32.71 ? 112 MET A SD 1 ATOM 884 C CE . MET A 1 111 ? -47.872 23.137 -22.782 1.00 30.88 ? 112 MET A CE 1 ATOM 885 N N . VAL A 1 112 ? -53.163 25.714 -21.871 1.00 25.91 ? 113 VAL A N 1 ATOM 886 C CA . VAL A 1 112 ? -54.314 26.210 -22.571 1.00 25.62 ? 113 VAL A CA 1 ATOM 887 C C . VAL A 1 112 ? -53.827 26.726 -23.927 1.00 25.78 ? 113 VAL A C 1 ATOM 888 O O . VAL A 1 112 ? -53.061 27.658 -23.973 1.00 23.83 ? 113 VAL A O 1 ATOM 889 C CB . VAL A 1 112 ? -55.024 27.374 -21.846 1.00 23.67 ? 113 VAL A CB 1 ATOM 890 C CG1 . VAL A 1 112 ? -56.266 27.839 -22.642 1.00 24.74 ? 113 VAL A CG1 1 ATOM 891 C CG2 . VAL A 1 112 ? -55.474 26.936 -20.508 1.00 24.79 ? 113 VAL A CG2 1 ATOM 892 N N . TRP A 1 113 ? -54.358 26.130 -24.988 1.00 27.60 ? 114 TRP A N 1 ATOM 893 C CA . TRP A 1 113 ? -53.930 26.334 -26.377 1.00 26.38 ? 114 TRP A CA 1 ATOM 894 C C . TRP A 1 113 ? -54.811 27.390 -27.022 1.00 25.37 ? 114 TRP A C 1 ATOM 895 O O . TRP A 1 113 ? -56.033 27.328 -26.963 1.00 22.58 ? 114 TRP A O 1 ATOM 896 C CB . TRP A 1 113 ? -54.019 25.006 -27.160 1.00 27.71 ? 114 TRP A CB 1 ATOM 897 C CG . TRP A 1 113 ? -53.803 25.159 -28.642 1.00 27.24 ? 114 TRP A CG 1 ATOM 898 C CD1 . TRP A 1 113 ? -54.731 25.023 -29.633 1.00 29.20 ? 114 TRP A CD1 1 ATOM 899 C CD2 . TRP A 1 113 ? -52.586 25.504 -29.264 1.00 25.25 ? 114 TRP A CD2 1 ATOM 900 N NE1 . TRP A 1 113 ? -54.132 25.237 -30.887 1.00 30.60 ? 114 TRP A NE1 1 ATOM 901 C CE2 . TRP A 1 113 ? -52.823 25.567 -30.663 1.00 28.07 ? 114 TRP A CE2 1 ATOM 902 C CE3 . TRP A 1 113 ? -51.299 25.741 -28.777 1.00 26.35 ? 114 TRP A CE3 1 ATOM 903 C CZ2 . TRP A 1 113 ? -51.831 25.866 -31.560 1.00 28.58 ? 114 TRP A CZ2 1 ATOM 904 C CZ3 . TRP A 1 113 ? -50.318 26.035 -29.644 1.00 28.98 ? 114 TRP A CZ3 1 ATOM 905 C CH2 . TRP A 1 113 ? -50.566 26.100 -31.042 1.00 29.18 ? 114 TRP A CH2 1 ATOM 906 N N . ILE A 1 114 ? -54.176 28.402 -27.593 1.00 26.45 ? 115 ILE A N 1 ATOM 907 C CA . ILE A 1 114 ? -54.907 29.432 -28.364 1.00 23.48 ? 115 ILE A CA 1 ATOM 908 C C . ILE A 1 114 ? -54.537 29.329 -29.861 1.00 23.18 ? 115 ILE A C 1 ATOM 909 O O . ILE A 1 114 ? -53.424 29.593 -30.274 1.00 18.93 ? 115 ILE A O 1 ATOM 910 C CB . ILE A 1 114 ? -54.523 30.821 -27.853 1.00 25.05 ? 115 ILE A CB 1 ATOM 911 C CG1 . ILE A 1 114 ? -54.831 30.912 -26.325 1.00 24.97 ? 115 ILE A CG1 1 ATOM 912 C CG2 . ILE A 1 114 ? -55.303 31.872 -28.661 1.00 23.65 ? 115 ILE A CG2 1 ATOM 913 C CD1 . ILE A 1 114 ? -54.423 32.222 -25.692 1.00 25.24 ? 115 ILE A CD1 1 ATOM 914 N N . TYR A 1 115 ? -55.500 28.936 -30.686 1.00 26.86 ? 116 TYR A N 1 ATOM 915 C CA . TYR A 1 115 ? -55.217 28.760 -32.106 1.00 25.79 ? 116 TYR A CA 1 ATOM 916 C C . TYR A 1 115 ? -54.803 30.031 -32.833 1.00 26.76 ? 116 TYR A C 1 ATOM 917 O O . TYR A 1 115 ? -55.236 31.141 -32.483 1.00 24.66 ? 116 TYR A O 1 ATOM 918 C CB . TYR A 1 115 ? -56.343 28.040 -32.814 1.00 23.52 ? 116 TYR A CB 1 ATOM 919 C CG . TYR A 1 115 ? -57.655 28.652 -32.796 1.00 22.51 ? 116 TYR A CG 1 ATOM 920 C CD1 . TYR A 1 115 ? -57.919 29.793 -33.517 1.00 23.31 ? 116 TYR A CD1 1 ATOM 921 C CD2 . TYR A 1 115 ? -58.697 28.061 -32.141 1.00 22.73 ? 116 TYR A CD2 1 ATOM 922 C CE1 . TYR A 1 115 ? -59.172 30.325 -33.564 1.00 20.64 ? 116 TYR A CE1 1 ATOM 923 C CE2 . TYR A 1 115 ? -59.985 28.624 -32.187 1.00 19.62 ? 116 TYR A CE2 1 ATOM 924 C CZ . TYR A 1 115 ? -60.201 29.742 -32.874 1.00 20.12 ? 116 TYR A CZ 1 ATOM 925 O OH . TYR A 1 115 ? -61.462 30.368 -32.869 1.00 20.81 ? 116 TYR A OH 1 ATOM 926 N N . GLY A 1 116 ? -53.918 29.824 -33.830 1.00 29.74 ? 117 GLY A N 1 ATOM 927 C CA . GLY A 1 116 ? -53.556 30.868 -34.811 1.00 26.28 ? 117 GLY A CA 1 ATOM 928 C C . GLY A 1 116 ? -54.529 30.882 -35.986 1.00 24.44 ? 117 GLY A C 1 ATOM 929 O O . GLY A 1 116 ? -55.602 30.216 -35.974 1.00 27.20 ? 117 GLY A O 1 ATOM 930 N N . GLY A 1 117 ? -54.164 31.625 -37.022 1.00 24.26 ? 118 GLY A N 1 ATOM 931 C CA . GLY A 1 117 ? -55.025 31.794 -38.226 1.00 23.27 ? 118 GLY A CA 1 ATOM 932 C C . GLY A 1 117 ? -55.227 33.265 -38.585 1.00 25.40 ? 118 GLY A C 1 ATOM 933 O O . GLY A 1 117 ? -56.272 33.640 -39.105 1.00 25.76 ? 118 GLY A O 1 ATOM 934 N N . GLY A 1 118 ? -54.259 34.119 -38.257 1.00 24.13 ? 119 GLY A N 1 ATOM 935 C CA . GLY A 1 118 ? -54.294 35.536 -38.677 1.00 25.31 ? 119 GLY A CA 1 ATOM 936 C C . GLY A 1 118 ? -55.397 36.406 -38.114 1.00 24.97 ? 119 GLY A C 1 ATOM 937 O O . GLY A 1 118 ? -55.640 37.518 -38.580 1.00 23.88 ? 119 GLY A O 1 ATOM 938 N N . PHE A 1 119 ? -56.087 35.868 -37.131 1.00 24.96 ? 120 PHE A N 1 ATOM 939 C CA . PHE A 1 119 ? -57.262 36.533 -36.513 1.00 24.33 ? 120 PHE A CA 1 ATOM 940 C C . PHE A 1 119 ? -58.437 36.566 -37.455 1.00 26.34 ? 120 PHE A C 1 ATOM 941 O O . PHE A 1 119 ? -59.486 37.153 -37.084 1.00 24.82 ? 120 PHE A O 1 ATOM 942 C CB . PHE A 1 119 ? -56.993 37.957 -36.069 1.00 23.39 ? 120 PHE A CB 1 ATOM 943 C CG . PHE A 1 119 ? -55.961 38.082 -35.014 1.00 22.83 ? 120 PHE A CG 1 ATOM 944 C CD1 . PHE A 1 119 ? -56.221 37.640 -33.725 1.00 22.45 ? 120 PHE A CD1 1 ATOM 945 C CD2 . PHE A 1 119 ? -54.766 38.702 -35.284 1.00 23.08 ? 120 PHE A CD2 1 ATOM 946 C CE1 . PHE A 1 119 ? -55.300 37.808 -32.725 1.00 23.63 ? 120 PHE A CE1 1 ATOM 947 C CE2 . PHE A 1 119 ? -53.802 38.831 -34.293 1.00 23.73 ? 120 PHE A CE2 1 ATOM 948 C CZ . PHE A 1 119 ? -54.093 38.417 -33.009 1.00 24.21 ? 120 PHE A CZ 1 ATOM 949 N N . TYR A 1 120 ? -58.285 35.935 -38.637 1.00 25.72 ? 121 TYR A N 1 ATOM 950 C CA . TYR A 1 120 ? -59.441 35.779 -39.592 1.00 26.48 ? 121 TYR A CA 1 ATOM 951 C C . TYR A 1 120 ? -59.959 34.366 -39.744 1.00 27.12 ? 121 TYR A C 1 ATOM 952 O O . TYR A 1 120 ? -61.022 34.146 -40.384 1.00 27.76 ? 121 TYR A O 1 ATOM 953 C CB . TYR A 1 120 ? -59.071 36.280 -40.997 1.00 23.38 ? 121 TYR A CB 1 ATOM 954 C CG . TYR A 1 120 ? -58.089 35.444 -41.714 1.00 21.18 ? 121 TYR A CG 1 ATOM 955 C CD1 . TYR A 1 120 ? -58.495 34.348 -42.480 1.00 24.76 ? 121 TYR A CD1 1 ATOM 956 C CD2 . TYR A 1 120 ? -56.722 35.701 -41.602 1.00 23.54 ? 121 TYR A CD2 1 ATOM 957 C CE1 . TYR A 1 120 ? -57.555 33.528 -43.164 1.00 25.17 ? 121 TYR A CE1 1 ATOM 958 C CE2 . TYR A 1 120 ? -55.768 34.929 -42.258 1.00 24.10 ? 121 TYR A CE2 1 ATOM 959 C CZ . TYR A 1 120 ? -56.195 33.814 -43.056 1.00 28.54 ? 121 TYR A CZ 1 ATOM 960 O OH . TYR A 1 120 ? -55.248 33.001 -43.723 1.00 29.88 ? 121 TYR A OH 1 ATOM 961 N N . SER A 1 121 ? -59.220 33.416 -39.171 1.00 23.77 ? 122 SER A N 1 ATOM 962 C CA . SER A 1 121 ? -59.567 32.028 -39.287 1.00 25.78 ? 122 SER A CA 1 ATOM 963 C C . SER A 1 121 ? -59.034 31.273 -38.062 1.00 25.42 ? 122 SER A C 1 ATOM 964 O O . SER A 1 121 ? -58.335 31.863 -37.224 1.00 24.75 ? 122 SER A O 1 ATOM 965 C CB . SER A 1 121 ? -58.906 31.451 -40.545 1.00 24.22 ? 122 SER A CB 1 ATOM 966 O OG . SER A 1 121 ? -57.506 31.529 -40.414 1.00 23.22 ? 122 SER A OG 1 ATOM 967 N N . GLY A 1 122 ? -59.310 29.971 -38.034 1.00 24.00 ? 123 GLY A N 1 ATOM 968 C CA . GLY A 1 122 ? -58.792 29.060 -37.008 1.00 28.52 ? 123 GLY A CA 1 ATOM 969 C C . GLY A 1 122 ? -59.885 28.289 -36.264 1.00 27.40 ? 123 GLY A C 1 ATOM 970 O O . GLY A 1 122 ? -61.018 28.744 -36.182 1.00 24.02 ? 123 GLY A O 1 ATOM 971 N N . SER A 1 123 ? -59.521 27.122 -35.727 1.00 26.33 ? 124 SER A N 1 ATOM 972 C CA . SER A 1 123 ? -60.448 26.198 -35.114 1.00 27.73 ? 124 SER A CA 1 ATOM 973 C C . SER A 1 123 ? -59.759 25.446 -33.985 1.00 27.00 ? 124 SER A C 1 ATOM 974 O O . SER A 1 123 ? -58.607 25.047 -34.094 1.00 28.63 ? 124 SER A O 1 ATOM 975 C CB . SER A 1 123 ? -60.934 25.174 -36.149 1.00 28.25 ? 124 SER A CB 1 ATOM 976 O OG . SER A 1 123 ? -61.761 25.820 -37.080 1.00 30.70 ? 124 SER A OG 1 ATOM 977 N N . SER A 1 124 ? -60.476 25.231 -32.897 1.00 29.36 ? 125 SER A N 1 ATOM 978 C CA . SER A 1 124 ? -59.950 24.461 -31.783 1.00 30.68 ? 125 SER A CA 1 ATOM 979 C C . SER A 1 124 ? -59.936 22.944 -32.028 1.00 30.09 ? 125 SER A C 1 ATOM 980 O O . SER A 1 124 ? -59.278 22.218 -31.290 1.00 32.82 ? 125 SER A O 1 ATOM 981 C CB . SER A 1 124 ? -60.765 24.736 -30.521 1.00 29.78 ? 125 SER A CB 1 ATOM 982 O OG . SER A 1 124 ? -62.030 24.111 -30.586 1.00 27.03 ? 125 SER A OG 1 ATOM 983 N N . THR A 1 125 ? -60.612 22.524 -33.080 1.00 30.04 ? 126 THR A N 1 ATOM 984 C CA . THR A 1 125 ? -61.027 21.133 -33.356 1.00 31.79 ? 126 THR A CA 1 ATOM 985 C C . THR A 1 125 ? -60.218 20.439 -34.424 1.00 31.91 ? 126 THR A C 1 ATOM 986 O O . THR A 1 125 ? -60.492 19.332 -34.783 1.00 33.01 ? 126 THR A O 1 ATOM 987 C CB . THR A 1 125 ? -62.484 21.109 -33.847 1.00 30.65 ? 126 THR A CB 1 ATOM 988 O OG1 . THR A 1 125 ? -62.644 21.977 -34.970 1.00 26.99 ? 126 THR A OG1 1 ATOM 989 C CG2 . THR A 1 125 ? -63.407 21.627 -32.783 1.00 33.08 ? 126 THR A CG2 1 ATOM 990 N N . LEU A 1 126 ? -59.163 21.073 -34.903 1.00 35.23 ? 127 LEU A N 1 ATOM 991 C CA . LEU A 1 126 ? -58.328 20.475 -35.911 1.00 31.73 ? 127 LEU A CA 1 ATOM 992 C C . LEU A 1 126 ? -57.589 19.236 -35.418 1.00 35.77 ? 127 LEU A C 1 ATOM 993 O O . LEU A 1 126 ? -57.202 19.117 -34.242 1.00 35.19 ? 127 LEU A O 1 ATOM 994 C CB . LEU A 1 126 ? -57.312 21.484 -36.421 1.00 30.57 ? 127 LEU A CB 1 ATOM 995 C CG . LEU A 1 126 ? -57.820 22.812 -36.970 1.00 31.40 ? 127 LEU A CG 1 ATOM 996 C CD1 . LEU A 1 126 ? -56.620 23.609 -37.469 1.00 30.90 ? 127 LEU A CD1 1 ATOM 997 C CD2 . LEU A 1 126 ? -58.869 22.595 -38.028 1.00 30.78 ? 127 LEU A CD2 1 ATOM 998 N N . ASP A 1 127 ? -57.311 18.351 -36.361 1.00 35.76 ? 128 ASP A N 1 ATOM 999 C CA . ASP A 1 127 ? -56.553 17.160 -36.048 1.00 36.27 ? 128 ASP A CA 1 ATOM 1000 C C . ASP A 1 127 ? -55.244 17.543 -35.414 1.00 33.58 ? 128 ASP A C 1 ATOM 1001 O O . ASP A 1 127 ? -54.859 16.921 -34.453 1.00 34.42 ? 128 ASP A O 1 ATOM 1002 C CB . ASP A 1 127 ? -56.376 16.255 -37.301 1.00 36.43 ? 128 ASP A CB 1 ATOM 1003 C CG . ASP A 1 127 ? -57.727 15.649 -37.808 1.00 43.79 ? 128 ASP A CG 1 ATOM 1004 O OD1 . ASP A 1 127 ? -58.719 15.627 -37.054 1.00 43.32 ? 128 ASP A OD1 1 ATOM 1005 O OD2 . ASP A 1 127 ? -57.825 15.212 -38.979 1.00 56.37 ? 128 ASP A OD2 1 ATOM 1006 N N . VAL A 1 128 ? -54.513 18.524 -35.949 1.00 33.92 ? 129 VAL A N 1 ATOM 1007 C CA . VAL A 1 128 ? -53.178 18.792 -35.384 1.00 32.21 ? 129 VAL A CA 1 ATOM 1008 C C . VAL A 1 128 ? -53.273 19.407 -33.980 1.00 29.64 ? 129 VAL A C 1 ATOM 1009 O O . VAL A 1 128 ? -52.255 19.620 -33.328 1.00 28.59 ? 129 VAL A O 1 ATOM 1010 C CB . VAL A 1 128 ? -52.350 19.863 -36.114 1.00 32.40 ? 129 VAL A CB 1 ATOM 1011 C CG1 . VAL A 1 128 ? -51.310 19.272 -36.944 1.00 34.89 ? 129 VAL A CG1 1 ATOM 1012 C CG2 . VAL A 1 128 ? -53.224 20.903 -36.814 1.00 35.06 ? 129 VAL A CG2 1 ATOM 1013 N N . TYR A 1 129 ? -54.452 19.842 -33.566 1.00 30.49 ? 130 TYR A N 1 ATOM 1014 C CA . TYR A 1 129 ? -54.583 20.420 -32.220 1.00 31.48 ? 130 TYR A CA 1 ATOM 1015 C C . TYR A 1 129 ? -55.212 19.433 -31.210 1.00 33.04 ? 130 TYR A C 1 ATOM 1016 O O . TYR A 1 129 ? -55.576 19.830 -30.104 1.00 38.04 ? 130 TYR A O 1 ATOM 1017 C CB . TYR A 1 129 ? -55.414 21.710 -32.237 1.00 30.03 ? 130 TYR A CB 1 ATOM 1018 C CG . TYR A 1 129 ? -54.962 22.851 -33.102 1.00 28.23 ? 130 TYR A CG 1 ATOM 1019 C CD1 . TYR A 1 129 ? -53.661 23.045 -33.447 1.00 30.68 ? 130 TYR A CD1 1 ATOM 1020 C CD2 . TYR A 1 129 ? -55.915 23.730 -33.610 1.00 30.77 ? 130 TYR A CD2 1 ATOM 1021 C CE1 . TYR A 1 129 ? -53.296 24.096 -34.280 1.00 28.56 ? 130 TYR A CE1 1 ATOM 1022 C CE2 . TYR A 1 129 ? -55.580 24.794 -34.376 1.00 27.85 ? 130 TYR A CE2 1 ATOM 1023 C CZ . TYR A 1 129 ? -54.284 24.974 -34.728 1.00 27.82 ? 130 TYR A CZ 1 ATOM 1024 O OH . TYR A 1 129 ? -54.006 26.063 -35.509 1.00 27.74 ? 130 TYR A OH 1 ATOM 1025 N N . ASN A 1 130 ? -55.309 18.153 -31.558 1.00 38.16 ? 131 ASN A N 1 ATOM 1026 C CA . ASN A 1 130 ? -55.863 17.134 -30.646 1.00 37.70 ? 131 ASN A CA 1 ATOM 1027 C C . ASN A 1 130 ? -55.019 17.002 -29.401 1.00 30.99 ? 131 ASN A C 1 ATOM 1028 O O . ASN A 1 130 ? -53.852 16.575 -29.434 1.00 28.00 ? 131 ASN A O 1 ATOM 1029 C CB . ASN A 1 130 ? -55.990 15.776 -31.339 1.00 41.01 ? 131 ASN A CB 1 ATOM 1030 C CG . ASN A 1 130 ? -56.851 14.799 -30.560 1.00 45.40 ? 131 ASN A CG 1 ATOM 1031 O OD1 . ASN A 1 130 ? -56.968 14.837 -29.334 1.00 44.99 ? 131 ASN A OD1 1 ATOM 1032 N ND2 . ASN A 1 130 ? -57.489 13.931 -31.287 1.00 51.57 ? 131 ASN A ND2 1 ATOM 1033 N N . GLY A 1 131 ? -55.602 17.394 -28.286 1.00 32.26 ? 132 GLY A N 1 ATOM 1034 C CA . GLY A 1 131 ? -54.811 17.421 -27.022 1.00 37.52 ? 132 GLY A CA 1 ATOM 1035 C C . GLY A 1 131 ? -54.461 16.092 -26.314 1.00 33.31 ? 132 GLY A C 1 ATOM 1036 O O . GLY A 1 131 ? -53.606 16.060 -25.397 1.00 33.57 ? 132 GLY A O 1 ATOM 1037 N N . LYS A 1 132 ? -55.059 15.009 -26.791 1.00 34.18 ? 133 LYS A N 1 ATOM 1038 C CA . LYS A 1 132 ? -54.955 13.716 -26.119 1.00 38.46 ? 133 LYS A CA 1 ATOM 1039 C C . LYS A 1 132 ? -53.572 13.190 -26.011 1.00 37.50 ? 133 LYS A C 1 ATOM 1040 O O . LYS A 1 132 ? -53.240 12.683 -24.942 1.00 40.16 ? 133 LYS A O 1 ATOM 1041 C CB . LYS A 1 132 ? -55.911 12.671 -26.693 1.00 36.86 ? 133 LYS A CB 1 ATOM 1042 C CG . LYS A 1 132 ? -55.402 11.914 -27.894 1.00 38.74 ? 133 LYS A CG 1 ATOM 1043 C CD . LYS A 1 132 ? -56.550 11.342 -28.682 1.00 36.19 ? 133 LYS A CD 1 ATOM 1044 C CE . LYS A 1 132 ? -56.002 10.364 -29.714 1.00 39.23 ? 133 LYS A CE 1 ATOM 1045 N NZ . LYS A 1 132 ? -57.181 9.682 -30.347 1.00 40.80 ? 133 LYS A NZ 1 ATOM 1046 N N . TYR A 1 133 ? -52.732 13.365 -27.036 1.00 38.56 ? 134 TYR A N 1 ATOM 1047 C CA . TYR A 1 133 ? -51.385 12.782 -26.971 1.00 38.12 ? 134 TYR A CA 1 ATOM 1048 C C . TYR A 1 133 ? -50.565 13.466 -25.925 1.00 37.42 ? 134 TYR A C 1 ATOM 1049 O O . TYR A 1 133 ? -49.729 12.848 -25.284 1.00 46.46 ? 134 TYR A O 1 ATOM 1050 C CB . TYR A 1 133 ? -50.637 12.850 -28.331 1.00 40.15 ? 134 TYR A CB 1 ATOM 1051 C CG . TYR A 1 133 ? -51.476 12.339 -29.471 1.00 43.10 ? 134 TYR A CG 1 ATOM 1052 C CD1 . TYR A 1 133 ? -51.721 10.957 -29.630 1.00 46.00 ? 134 TYR A CD1 1 ATOM 1053 C CD2 . TYR A 1 133 ? -52.066 13.215 -30.363 1.00 38.41 ? 134 TYR A CD2 1 ATOM 1054 C CE1 . TYR A 1 133 ? -52.550 10.478 -30.647 1.00 43.28 ? 134 TYR A CE1 1 ATOM 1055 C CE2 . TYR A 1 133 ? -52.892 12.746 -31.390 1.00 38.76 ? 134 TYR A CE2 1 ATOM 1056 C CZ . TYR A 1 133 ? -53.120 11.380 -31.518 1.00 43.96 ? 134 TYR A CZ 1 ATOM 1057 O OH . TYR A 1 133 ? -53.929 10.926 -32.531 1.00 55.00 ? 134 TYR A OH 1 ATOM 1058 N N . LEU A 1 134 ? -50.722 14.767 -25.814 1.00 36.24 ? 135 LEU A N 1 ATOM 1059 C CA . LEU A 1 134 ? -49.913 15.574 -24.854 1.00 38.56 ? 135 LEU A CA 1 ATOM 1060 C C . LEU A 1 134 ? -50.420 15.413 -23.426 1.00 35.26 ? 135 LEU A C 1 ATOM 1061 O O . LEU A 1 134 ? -49.653 15.265 -22.500 1.00 36.52 ? 135 LEU A O 1 ATOM 1062 C CB . LEU A 1 134 ? -49.990 17.077 -25.236 1.00 36.45 ? 135 LEU A CB 1 ATOM 1063 C CG . LEU A 1 134 ? -49.067 18.118 -24.623 1.00 35.55 ? 135 LEU A CG 1 ATOM 1064 C CD1 . LEU A 1 134 ? -47.596 17.768 -24.576 1.00 35.62 ? 135 LEU A CD1 1 ATOM 1065 C CD2 . LEU A 1 134 ? -49.223 19.409 -25.421 1.00 35.16 ? 135 LEU A CD2 1 ATOM 1066 N N . ALA A 1 135 ? -51.728 15.501 -23.266 1.00 34.24 ? 136 ALA A N 1 ATOM 1067 C CA . ALA A 1 135 ? -52.336 15.261 -21.987 1.00 39.94 ? 136 ALA A CA 1 ATOM 1068 C C . ALA A 1 135 ? -51.871 13.892 -21.446 1.00 42.12 ? 136 ALA A C 1 ATOM 1069 O O . ALA A 1 135 ? -51.373 13.782 -20.332 1.00 41.50 ? 136 ALA A O 1 ATOM 1070 C CB . ALA A 1 135 ? -53.837 15.293 -22.141 1.00 36.37 ? 136 ALA A CB 1 ATOM 1071 N N . TYR A 1 136 ? -52.003 12.866 -22.277 1.00 44.88 ? 137 TYR A N 1 ATOM 1072 C CA . TYR A 1 136 ? -51.631 11.517 -21.908 1.00 43.72 ? 137 TYR A CA 1 ATOM 1073 C C . TYR A 1 136 ? -50.150 11.386 -21.698 1.00 42.07 ? 137 TYR A C 1 ATOM 1074 O O . TYR A 1 136 ? -49.710 10.884 -20.673 1.00 42.43 ? 137 TYR A O 1 ATOM 1075 C CB . TYR A 1 136 ? -52.115 10.522 -22.961 1.00 45.05 ? 137 TYR A CB 1 ATOM 1076 C CG . TYR A 1 136 ? -51.592 9.158 -22.746 1.00 46.79 ? 137 TYR A CG 1 ATOM 1077 C CD1 . TYR A 1 136 ? -52.148 8.311 -21.748 1.00 49.84 ? 137 TYR A CD1 1 ATOM 1078 C CD2 . TYR A 1 136 ? -50.520 8.686 -23.494 1.00 47.60 ? 137 TYR A CD2 1 ATOM 1079 C CE1 . TYR A 1 136 ? -51.626 7.027 -21.515 1.00 49.88 ? 137 TYR A CE1 1 ATOM 1080 C CE2 . TYR A 1 136 ? -49.995 7.392 -23.284 1.00 52.87 ? 137 TYR A CE2 1 ATOM 1081 C CZ . TYR A 1 136 ? -50.550 6.565 -22.304 1.00 52.30 ? 137 TYR A CZ 1 ATOM 1082 O OH . TYR A 1 136 ? -50.030 5.316 -22.116 1.00 49.18 ? 137 TYR A OH 1 ATOM 1083 N N . THR A 1 137 ? -49.350 11.857 -22.640 1.00 40.40 ? 138 THR A N 1 ATOM 1084 C CA . THR A 1 137 ? -47.894 11.602 -22.541 1.00 39.16 ? 138 THR A CA 1 ATOM 1085 C C . THR A 1 137 ? -47.282 12.324 -21.370 1.00 38.33 ? 138 THR A C 1 ATOM 1086 O O . THR A 1 137 ? -46.421 11.783 -20.713 1.00 41.63 ? 138 THR A O 1 ATOM 1087 C CB . THR A 1 137 ? -47.131 11.959 -23.833 1.00 37.81 ? 138 THR A CB 1 ATOM 1088 O OG1 . THR A 1 137 ? -47.609 11.132 -24.878 1.00 43.02 ? 138 THR A OG1 1 ATOM 1089 C CG2 . THR A 1 137 ? -45.671 11.696 -23.708 1.00 37.65 ? 138 THR A CG2 1 ATOM 1090 N N . GLU A 1 138 ? -47.735 13.543 -21.090 1.00 39.50 ? 139 GLU A N 1 ATOM 1091 C CA . GLU A 1 138 ? -47.034 14.402 -20.146 1.00 37.28 ? 139 GLU A CA 1 ATOM 1092 C C . GLU A 1 138 ? -47.858 14.661 -18.911 1.00 35.09 ? 139 GLU A C 1 ATOM 1093 O O . GLU A 1 138 ? -47.365 15.342 -18.025 1.00 36.37 ? 139 GLU A O 1 ATOM 1094 C CB . GLU A 1 138 ? -46.670 15.768 -20.798 1.00 36.67 ? 139 GLU A CB 1 ATOM 1095 C CG . GLU A 1 138 ? -45.552 15.750 -21.803 1.00 34.88 ? 139 GLU A CG 1 ATOM 1096 C CD . GLU A 1 138 ? -44.230 15.328 -21.273 1.00 39.60 ? 139 GLU A CD 1 ATOM 1097 O OE1 . GLU A 1 138 ? -43.802 15.813 -20.204 1.00 40.06 ? 139 GLU A OE1 1 ATOM 1098 O OE2 . GLU A 1 138 ? -43.552 14.564 -22.003 1.00 42.67 ? 139 GLU A OE2 1 ATOM 1099 N N . GLU A 1 139 ? -49.097 14.154 -18.846 1.00 39.06 ? 140 GLU A N 1 ATOM 1100 C CA . GLU A 1 139 ? -49.910 14.200 -17.620 1.00 42.12 ? 140 GLU A CA 1 ATOM 1101 C C . GLU A 1 139 ? -50.214 15.658 -17.260 1.00 42.63 ? 140 GLU A C 1 ATOM 1102 O O . GLU A 1 139 ? -49.893 16.146 -16.170 1.00 46.91 ? 140 GLU A O 1 ATOM 1103 C CB . GLU A 1 139 ? -49.193 13.439 -16.461 1.00 50.03 ? 140 GLU A CB 1 ATOM 1104 C CG . GLU A 1 139 ? -49.668 11.982 -16.243 1.00 65.33 ? 140 GLU A CG 1 ATOM 1105 C CD . GLU A 1 139 ? -48.529 10.953 -16.019 1.00 76.88 ? 140 GLU A CD 1 ATOM 1106 O OE1 . GLU A 1 139 ? -47.428 11.252 -15.453 1.00 74.81 ? 140 GLU A OE1 1 ATOM 1107 O OE2 . GLU A 1 139 ? -48.744 9.795 -16.431 1.00 87.46 ? 140 GLU A OE2 1 ATOM 1108 N N . VAL A 1 140 ? -50.809 16.362 -18.221 1.00 36.85 ? 141 VAL A N 1 ATOM 1109 C CA . VAL A 1 140 ? -51.233 17.707 -18.022 1.00 30.70 ? 141 VAL A CA 1 ATOM 1110 C C . VAL A 1 140 ? -52.667 17.649 -18.385 1.00 30.83 ? 141 VAL A C 1 ATOM 1111 O O . VAL A 1 140 ? -53.114 16.774 -19.140 1.00 30.25 ? 141 VAL A O 1 ATOM 1112 C CB . VAL A 1 140 ? -50.457 18.732 -18.911 1.00 35.33 ? 141 VAL A CB 1 ATOM 1113 C CG1 . VAL A 1 140 ? -48.963 18.753 -18.595 1.00 32.33 ? 141 VAL A CG1 1 ATOM 1114 C CG2 . VAL A 1 140 ? -50.606 18.467 -20.402 1.00 34.74 ? 141 VAL A CG2 1 ATOM 1115 N N . VAL A 1 141 ? -53.422 18.556 -17.805 1.00 31.71 ? 142 VAL A N 1 ATOM 1116 C CA . VAL A 1 141 ? -54.750 18.836 -18.272 1.00 31.89 ? 142 VAL A CA 1 ATOM 1117 C C . VAL A 1 141 ? -54.646 19.881 -19.421 1.00 34.36 ? 142 VAL A C 1 ATOM 1118 O O . VAL A 1 141 ? -54.035 20.948 -19.246 1.00 33.03 ? 142 VAL A O 1 ATOM 1119 C CB . VAL A 1 141 ? -55.529 19.439 -17.139 1.00 29.28 ? 142 VAL A CB 1 ATOM 1120 C CG1 . VAL A 1 141 ? -56.834 20.006 -17.597 1.00 30.76 ? 142 VAL A CG1 1 ATOM 1121 C CG2 . VAL A 1 141 ? -55.736 18.376 -16.098 1.00 34.15 ? 142 VAL A CG2 1 ATOM 1122 N N . LEU A 1 142 ? -55.204 19.532 -20.584 1.00 31.63 ? 143 LEU A N 1 ATOM 1123 C CA . LEU A 1 142 ? -54.936 20.255 -21.832 1.00 29.70 ? 143 LEU A CA 1 ATOM 1124 C C . LEU A 1 142 ? -56.209 20.852 -22.241 1.00 27.73 ? 143 LEU A C 1 ATOM 1125 O O . LEU A 1 142 ? -57.154 20.131 -22.577 1.00 31.59 ? 143 LEU A O 1 ATOM 1126 C CB . LEU A 1 142 ? -54.422 19.324 -22.928 1.00 33.30 ? 143 LEU A CB 1 ATOM 1127 C CG . LEU A 1 142 ? -53.719 19.938 -24.171 1.00 37.03 ? 143 LEU A CG 1 ATOM 1128 C CD1 . LEU A 1 142 ? -54.722 20.578 -25.117 1.00 39.88 ? 143 LEU A CD1 1 ATOM 1129 C CD2 . LEU A 1 142 ? -52.648 20.978 -23.846 1.00 37.65 ? 143 LEU A CD2 1 ATOM 1130 N N . VAL A 1 143 ? -56.272 22.177 -22.190 1.00 26.59 ? 144 VAL A N 1 ATOM 1131 C CA . VAL A 1 143 ? -57.436 22.878 -22.696 1.00 26.21 ? 144 VAL A CA 1 ATOM 1132 C C . VAL A 1 143 ? -57.186 23.517 -24.072 1.00 25.06 ? 144 VAL A C 1 ATOM 1133 O O . VAL A 1 143 ? -56.106 24.082 -24.340 1.00 26.41 ? 144 VAL A O 1 ATOM 1134 C CB . VAL A 1 143 ? -57.839 23.987 -21.715 1.00 25.33 ? 144 VAL A CB 1 ATOM 1135 C CG1 . VAL A 1 143 ? -59.066 24.744 -22.188 1.00 24.45 ? 144 VAL A CG1 1 ATOM 1136 C CG2 . VAL A 1 143 ? -58.141 23.383 -20.357 1.00 28.69 ? 144 VAL A CG2 1 ATOM 1137 N N . SER A 1 144 ? -58.217 23.541 -24.902 1.00 22.41 ? 145 SER A N 1 ATOM 1138 C CA . SER A 1 144 ? -58.135 24.375 -26.064 1.00 24.00 ? 145 SER A CA 1 ATOM 1139 C C . SER A 1 144 ? -59.353 25.252 -26.089 1.00 24.99 ? 145 SER A C 1 ATOM 1140 O O . SER A 1 144 ? -60.477 24.763 -26.065 1.00 21.99 ? 145 SER A O 1 ATOM 1141 C CB . SER A 1 144 ? -57.979 23.528 -27.350 1.00 24.61 ? 145 SER A CB 1 ATOM 1142 O OG . SER A 1 144 ? -59.176 22.794 -27.661 1.00 25.66 ? 145 SER A OG 1 ATOM 1143 N N . LEU A 1 145 ? -59.153 26.560 -26.196 1.00 24.52 ? 146 LEU A N 1 ATOM 1144 C CA . LEU A 1 145 ? -60.296 27.457 -26.269 1.00 25.98 ? 146 LEU A CA 1 ATOM 1145 C C . LEU A 1 145 ? -60.684 27.853 -27.741 1.00 26.63 ? 146 LEU A C 1 ATOM 1146 O O . LEU A 1 145 ? -60.033 27.490 -28.716 1.00 24.87 ? 146 LEU A O 1 ATOM 1147 C CB . LEU A 1 145 ? -59.954 28.712 -25.440 1.00 28.81 ? 146 LEU A CB 1 ATOM 1148 C CG . LEU A 1 145 ? -58.675 29.494 -25.717 1.00 30.08 ? 146 LEU A CG 1 ATOM 1149 C CD1 . LEU A 1 145 ? -58.773 30.366 -27.000 1.00 34.20 ? 146 LEU A CD1 1 ATOM 1150 C CD2 . LEU A 1 145 ? -58.307 30.395 -24.566 1.00 30.97 ? 146 LEU A CD2 1 ATOM 1151 N N . SER A 1 146 ? -61.711 28.669 -27.877 1.00 27.82 ? 147 SER A N 1 ATOM 1152 C CA . SER A 1 146 ? -62.001 29.271 -29.128 1.00 26.74 ? 147 SER A CA 1 ATOM 1153 C C . SER A 1 146 ? -62.306 30.734 -28.935 1.00 27.73 ? 147 SER A C 1 ATOM 1154 O O . SER A 1 146 ? -62.499 31.223 -27.819 1.00 25.84 ? 147 SER A O 1 ATOM 1155 C CB . SER A 1 146 ? -63.159 28.550 -29.775 1.00 28.42 ? 147 SER A CB 1 ATOM 1156 O OG . SER A 1 146 ? -64.332 28.664 -29.028 1.00 32.80 ? 147 SER A OG 1 ATOM 1157 N N . TYR A 1 147 ? -62.300 31.453 -30.046 1.00 28.64 ? 148 TYR A N 1 ATOM 1158 C CA . TYR A 1 147 ? -62.566 32.881 -30.091 1.00 23.98 ? 148 TYR A CA 1 ATOM 1159 C C . TYR A 1 147 ? -63.006 33.363 -31.487 1.00 25.11 ? 148 TYR A C 1 ATOM 1160 O O . TYR A 1 147 ? -62.589 32.819 -32.521 1.00 27.02 ? 148 TYR A O 1 ATOM 1161 C CB . TYR A 1 147 ? -61.332 33.650 -29.626 1.00 24.08 ? 148 TYR A CB 1 ATOM 1162 C CG . TYR A 1 147 ? -60.067 33.492 -30.467 1.00 24.50 ? 148 TYR A CG 1 ATOM 1163 C CD1 . TYR A 1 147 ? -59.192 32.468 -30.265 1.00 25.68 ? 148 TYR A CD1 1 ATOM 1164 C CD2 . TYR A 1 147 ? -59.756 34.403 -31.433 1.00 24.61 ? 148 TYR A CD2 1 ATOM 1165 C CE1 . TYR A 1 147 ? -58.073 32.335 -31.032 1.00 25.83 ? 148 TYR A CE1 1 ATOM 1166 C CE2 . TYR A 1 147 ? -58.650 34.273 -32.219 1.00 22.94 ? 148 TYR A CE2 1 ATOM 1167 C CZ . TYR A 1 147 ? -57.813 33.253 -32.033 1.00 24.49 ? 148 TYR A CZ 1 ATOM 1168 O OH . TYR A 1 147 ? -56.650 33.215 -32.810 1.00 23.49 ? 148 TYR A OH 1 ATOM 1169 N N . ARG A 1 148 ? -63.870 34.357 -31.504 1.00 24.83 ? 149 ARG A N 1 ATOM 1170 C CA . ARG A 1 148 ? -64.368 34.901 -32.719 1.00 26.97 ? 149 ARG A CA 1 ATOM 1171 C C . ARG A 1 148 ? -63.218 35.516 -33.525 1.00 30.00 ? 149 ARG A C 1 ATOM 1172 O O . ARG A 1 148 ? -62.360 36.247 -32.947 1.00 26.54 ? 149 ARG A O 1 ATOM 1173 C CB . ARG A 1 148 ? -65.371 35.998 -32.434 1.00 25.34 ? 149 ARG A CB 1 ATOM 1174 C CG . ARG A 1 148 ? -66.695 35.451 -31.981 1.00 28.48 ? 149 ARG A CG 1 ATOM 1175 C CD . ARG A 1 148 ? -67.634 36.586 -31.589 1.00 29.21 ? 149 ARG A CD 1 ATOM 1176 N NE . ARG A 1 148 ? -67.297 37.037 -30.222 1.00 28.03 ? 149 ARG A NE 1 ATOM 1177 C CZ . ARG A 1 148 ? -67.911 38.009 -29.585 1.00 26.85 ? 149 ARG A CZ 1 ATOM 1178 N NH1 . ARG A 1 148 ? -68.828 38.691 -30.193 1.00 28.04 ? 149 ARG A NH1 1 ATOM 1179 N NH2 . ARG A 1 148 ? -67.552 38.351 -28.336 1.00 28.93 ? 149 ARG A NH2 1 ATOM 1180 N N . VAL A 1 149 ? -63.239 35.237 -34.837 1.00 26.47 ? 150 VAL A N 1 ATOM 1181 C CA . VAL A 1 149 ? -62.246 35.779 -35.750 1.00 26.94 ? 150 VAL A CA 1 ATOM 1182 C C . VAL A 1 149 ? -62.937 36.668 -36.763 1.00 27.70 ? 150 VAL A C 1 ATOM 1183 O O . VAL A 1 149 ? -64.173 36.758 -36.824 1.00 29.46 ? 150 VAL A O 1 ATOM 1184 C CB . VAL A 1 149 ? -61.462 34.650 -36.429 1.00 27.14 ? 150 VAL A CB 1 ATOM 1185 C CG1 . VAL A 1 149 ? -60.698 33.807 -35.384 1.00 29.34 ? 150 VAL A CG1 1 ATOM 1186 C CG2 . VAL A 1 149 ? -62.377 33.713 -37.195 1.00 25.49 ? 150 VAL A CG2 1 ATOM 1187 N N . GLY A 1 150 ? -62.140 37.325 -37.586 1.00 30.85 ? 151 GLY A N 1 ATOM 1188 C CA . GLY A 1 150 ? -62.668 38.127 -38.669 1.00 26.43 ? 151 GLY A CA 1 ATOM 1189 C C . GLY A 1 150 ? -63.383 39.313 -38.052 1.00 29.71 ? 151 GLY A C 1 ATOM 1190 O O . GLY A 1 150 ? -63.084 39.758 -36.947 1.00 31.25 ? 151 GLY A O 1 ATOM 1191 N N . ALA A 1 151 ? -64.337 39.828 -38.782 1.00 29.46 ? 152 ALA A N 1 ATOM 1192 C CA . ALA A 1 151 ? -65.067 40.983 -38.347 1.00 32.04 ? 152 ALA A CA 1 ATOM 1193 C C . ALA A 1 151 ? -65.880 40.677 -37.106 1.00 28.26 ? 152 ALA A C 1 ATOM 1194 O O . ALA A 1 151 ? -66.044 41.533 -36.291 1.00 25.86 ? 152 ALA A O 1 ATOM 1195 C CB . ALA A 1 151 ? -66.005 41.413 -39.436 1.00 35.60 ? 152 ALA A CB 1 ATOM 1196 N N . PHE A 1 152 ? -66.312 39.432 -36.967 1.00 28.33 ? 153 PHE A N 1 ATOM 1197 C CA . PHE A 1 152 ? -67.047 38.999 -35.811 1.00 30.93 ? 153 PHE A CA 1 ATOM 1198 C C . PHE A 1 152 ? -66.244 39.183 -34.530 1.00 29.70 ? 153 PHE A C 1 ATOM 1199 O O . PHE A 1 152 ? -66.822 39.480 -33.494 1.00 28.66 ? 153 PHE A O 1 ATOM 1200 C CB . PHE A 1 152 ? -67.471 37.543 -35.948 1.00 31.35 ? 153 PHE A CB 1 ATOM 1201 C CG . PHE A 1 152 ? -68.140 37.249 -37.237 1.00 35.53 ? 153 PHE A CG 1 ATOM 1202 C CD1 . PHE A 1 152 ? -69.485 37.469 -37.398 1.00 40.27 ? 153 PHE A CD1 1 ATOM 1203 C CD2 . PHE A 1 152 ? -67.412 36.776 -38.319 1.00 37.76 ? 153 PHE A CD2 1 ATOM 1204 C CE1 . PHE A 1 152 ? -70.123 37.195 -38.602 1.00 38.36 ? 153 PHE A CE1 1 ATOM 1205 C CE2 . PHE A 1 152 ? -68.036 36.509 -39.521 1.00 39.29 ? 153 PHE A CE2 1 ATOM 1206 C CZ . PHE A 1 152 ? -69.386 36.726 -39.664 1.00 39.98 ? 153 PHE A CZ 1 ATOM 1207 N N . GLY A 1 153 ? -64.923 39.035 -34.608 1.00 28.75 ? 154 GLY A N 1 ATOM 1208 C CA . GLY A 1 153 ? -64.081 39.099 -33.419 1.00 28.40 ? 154 GLY A CA 1 ATOM 1209 C C . GLY A 1 153 ? -63.373 40.425 -33.294 1.00 28.66 ? 154 GLY A C 1 ATOM 1210 O O . GLY A 1 153 ? -62.906 40.778 -32.228 1.00 29.12 ? 154 GLY A O 1 ATOM 1211 N N . PHE A 1 154 ? -63.259 41.168 -34.388 1.00 27.28 ? 155 PHE A N 1 ATOM 1212 C CA . PHE A 1 154 ? -62.363 42.276 -34.390 1.00 26.42 ? 155 PHE A CA 1 ATOM 1213 C C . PHE A 1 154 ? -62.801 43.546 -35.089 1.00 28.56 ? 155 PHE A C 1 ATOM 1214 O O . PHE A 1 154 ? -62.011 44.500 -35.152 1.00 27.37 ? 155 PHE A O 1 ATOM 1215 C CB . PHE A 1 154 ? -61.033 41.767 -34.896 1.00 26.55 ? 155 PHE A CB 1 ATOM 1216 C CG . PHE A 1 154 ? -60.425 40.791 -33.971 1.00 24.92 ? 155 PHE A CG 1 ATOM 1217 C CD1 . PHE A 1 154 ? -59.859 41.213 -32.772 1.00 26.61 ? 155 PHE A CD1 1 ATOM 1218 C CD2 . PHE A 1 154 ? -60.522 39.460 -34.226 1.00 25.90 ? 155 PHE A CD2 1 ATOM 1219 C CE1 . PHE A 1 154 ? -59.349 40.286 -31.873 1.00 25.85 ? 155 PHE A CE1 1 ATOM 1220 C CE2 . PHE A 1 154 ? -60.043 38.526 -33.342 1.00 24.70 ? 155 PHE A CE2 1 ATOM 1221 C CZ . PHE A 1 154 ? -59.471 38.946 -32.143 1.00 25.88 ? 155 PHE A CZ 1 ATOM 1222 N N . LEU A 1 155 ? -64.057 43.610 -35.544 1.00 28.05 ? 156 LEU A N 1 ATOM 1223 C CA . LEU A 1 155 ? -64.549 44.881 -36.083 1.00 29.24 ? 156 LEU A CA 1 ATOM 1224 C C . LEU A 1 155 ? -64.440 45.909 -34.989 1.00 28.27 ? 156 LEU A C 1 ATOM 1225 O O . LEU A 1 155 ? -64.907 45.660 -33.910 1.00 34.82 ? 156 LEU A O 1 ATOM 1226 C CB . LEU A 1 155 ? -66.017 44.783 -36.535 1.00 31.65 ? 156 LEU A CB 1 ATOM 1227 C CG . LEU A 1 155 ? -66.530 46.027 -37.306 1.00 35.71 ? 156 LEU A CG 1 ATOM 1228 C CD1 . LEU A 1 155 ? -66.560 45.778 -38.821 1.00 36.96 ? 156 LEU A CD1 1 ATOM 1229 C CD2 . LEU A 1 155 ? -67.931 46.370 -36.865 1.00 34.57 ? 156 LEU A CD2 1 ATOM 1230 N N . ALA A 1 156 ? -63.893 47.082 -35.268 1.00 30.83 ? 157 ALA A N 1 ATOM 1231 C CA . ALA A 1 156 ? -63.610 48.048 -34.251 1.00 30.62 ? 157 ALA A CA 1 ATOM 1232 C C . ALA A 1 156 ? -64.049 49.471 -34.605 1.00 38.26 ? 157 ALA A C 1 ATOM 1233 O O . ALA A 1 156 ? -63.360 50.168 -35.395 1.00 32.47 ? 157 ALA A O 1 ATOM 1234 C CB . ALA A 1 156 ? -62.134 48.076 -33.961 1.00 29.59 ? 157 ALA A CB 1 ATOM 1235 N N . LEU A 1 157 ? -65.134 49.903 -33.942 1.00 33.68 ? 158 LEU A N 1 ATOM 1236 C CA . LEU A 1 157 ? -65.600 51.296 -33.987 1.00 35.67 ? 158 LEU A CA 1 ATOM 1237 C C . LEU A 1 157 ? -65.412 51.935 -32.623 1.00 32.80 ? 158 LEU A C 1 ATOM 1238 O O . LEU A 1 157 ? -66.312 52.014 -31.809 1.00 37.03 ? 158 LEU A O 1 ATOM 1239 C CB . LEU A 1 157 ? -67.078 51.317 -34.429 1.00 38.91 ? 158 LEU A CB 1 ATOM 1240 C CG . LEU A 1 157 ? -67.213 50.891 -35.925 1.00 38.58 ? 158 LEU A CG 1 ATOM 1241 C CD1 . LEU A 1 157 ? -68.602 50.378 -36.283 1.00 35.85 ? 158 LEU A CD1 1 ATOM 1242 C CD2 . LEU A 1 157 ? -66.754 52.006 -36.871 1.00 39.06 ? 158 LEU A CD2 1 ATOM 1243 N N . HIS A 1 158 ? -64.204 52.325 -32.339 1.00 34.80 ? 159 HIS A N 1 ATOM 1244 C CA . HIS A 1 158 ? -63.853 52.796 -31.020 1.00 39.55 ? 159 HIS A CA 1 ATOM 1245 C C . HIS A 1 158 ? -64.725 53.957 -30.566 1.00 49.11 ? 159 HIS A C 1 ATOM 1246 O O . HIS A 1 158 ? -64.977 54.874 -31.365 1.00 42.77 ? 159 HIS A O 1 ATOM 1247 C CB . HIS A 1 158 ? -62.440 53.275 -31.018 1.00 37.23 ? 159 HIS A CB 1 ATOM 1248 C CG . HIS A 1 158 ? -61.964 53.693 -29.677 1.00 42.71 ? 159 HIS A CG 1 ATOM 1249 N ND1 . HIS A 1 158 ? -61.902 52.817 -28.601 1.00 42.61 ? 159 HIS A ND1 1 ATOM 1250 C CD2 . HIS A 1 158 ? -61.482 54.886 -29.239 1.00 40.43 ? 159 HIS A CD2 1 ATOM 1251 C CE1 . HIS A 1 158 ? -61.405 53.462 -27.561 1.00 41.24 ? 159 HIS A CE1 1 ATOM 1252 N NE2 . HIS A 1 158 ? -61.149 54.717 -27.919 1.00 41.48 ? 159 HIS A NE2 1 ATOM 1253 N N . GLY A 1 159 ? -65.163 53.924 -29.295 1.00 46.39 ? 160 GLY A N 1 ATOM 1254 C CA . GLY A 1 159 ? -66.178 54.867 -28.800 1.00 49.67 ? 160 GLY A CA 1 ATOM 1255 C C . GLY A 1 159 ? -67.570 54.238 -28.824 1.00 47.52 ? 160 GLY A C 1 ATOM 1256 O O . GLY A 1 159 ? -68.431 54.584 -28.072 1.00 45.91 ? 160 GLY A O 1 ATOM 1257 N N . SER A 1 160 ? -67.804 53.284 -29.692 1.00 48.22 ? 161 SER A N 1 ATOM 1258 C CA . SER A 1 160 ? -69.069 52.593 -29.630 1.00 48.28 ? 161 SER A CA 1 ATOM 1259 C C . SER A 1 160 ? -68.933 51.466 -28.609 1.00 49.65 ? 161 SER A C 1 ATOM 1260 O O . SER A 1 160 ? -67.845 50.931 -28.419 1.00 53.78 ? 161 SER A O 1 ATOM 1261 C CB . SER A 1 160 ? -69.416 52.022 -30.993 1.00 50.42 ? 161 SER A CB 1 ATOM 1262 O OG . SER A 1 160 ? -70.225 50.869 -30.826 1.00 58.29 ? 161 SER A OG 1 ATOM 1263 N N . GLN A 1 161 ? -70.021 51.102 -27.944 1.00 46.10 ? 162 GLN A N 1 ATOM 1264 C CA . GLN A 1 161 ? -69.999 49.961 -27.046 1.00 45.86 ? 162 GLN A CA 1 ATOM 1265 C C . GLN A 1 161 ? -70.617 48.748 -27.697 1.00 42.76 ? 162 GLN A C 1 ATOM 1266 O O . GLN A 1 161 ? -70.590 47.639 -27.139 1.00 41.38 ? 162 GLN A O 1 ATOM 1267 C CB . GLN A 1 161 ? -70.702 50.294 -25.702 1.00 53.52 ? 162 GLN A CB 1 ATOM 1268 C CG . GLN A 1 161 ? -69.912 51.270 -24.815 1.00 57.79 ? 162 GLN A CG 1 ATOM 1269 C CD . GLN A 1 161 ? -68.478 50.795 -24.475 1.00 64.78 ? 162 GLN A CD 1 ATOM 1270 O OE1 . GLN A 1 161 ? -68.239 49.602 -24.218 1.00 63.77 ? 162 GLN A OE1 1 ATOM 1271 N NE2 . GLN A 1 161 ? -67.518 51.738 -24.468 1.00 61.86 ? 162 GLN A NE2 1 ATOM 1272 N N . GLU A 1 162 ? -71.227 48.956 -28.855 1.00 40.07 ? 163 GLU A N 1 ATOM 1273 C CA . GLU A 1 162 ? -71.840 47.851 -29.581 1.00 44.25 ? 163 GLU A CA 1 ATOM 1274 C C . GLU A 1 162 ? -70.784 47.053 -30.399 1.00 39.59 ? 163 GLU A C 1 ATOM 1275 O O . GLU A 1 162 ? -70.948 45.861 -30.553 1.00 47.09 ? 163 GLU A O 1 ATOM 1276 C CB . GLU A 1 162 ? -72.992 48.356 -30.465 1.00 50.78 ? 163 GLU A CB 1 ATOM 1277 C CG . GLU A 1 162 ? -74.158 49.046 -29.720 1.00 52.98 ? 163 GLU A CG 1 ATOM 1278 C CD . GLU A 1 162 ? -74.848 48.123 -28.729 1.00 54.56 ? 163 GLU A CD 1 ATOM 1279 O OE1 . GLU A 1 162 ? -75.111 46.935 -29.044 1.00 51.08 ? 163 GLU A OE1 1 ATOM 1280 O OE2 . GLU A 1 162 ? -75.113 48.586 -27.602 1.00 61.78 ? 163 GLU A OE2 1 ATOM 1281 N N . ALA A 1 163 ? -69.713 47.702 -30.872 1.00 37.38 ? 164 ALA A N 1 ATOM 1282 C CA . ALA A 1 163 ? -68.604 47.040 -31.616 1.00 37.81 ? 164 ALA A CA 1 ATOM 1283 C C . ALA A 1 163 ? -67.306 47.736 -31.260 1.00 33.85 ? 164 ALA A C 1 ATOM 1284 O O . ALA A 1 163 ? -66.744 48.502 -32.081 1.00 37.73 ? 164 ALA A O 1 ATOM 1285 C CB . ALA A 1 163 ? -68.836 47.096 -33.127 1.00 35.00 ? 164 ALA A CB 1 ATOM 1286 N N . PRO A 1 164 ? -66.833 47.508 -30.022 1.00 32.85 ? 165 PRO A N 1 ATOM 1287 C CA . PRO A 1 164 ? -65.730 48.264 -29.490 1.00 31.65 ? 165 PRO A CA 1 ATOM 1288 C C . PRO A 1 164 ? -64.426 47.860 -30.055 1.00 32.40 ? 165 PRO A C 1 ATOM 1289 O O . PRO A 1 164 ? -63.435 48.575 -29.875 1.00 32.27 ? 165 PRO A O 1 ATOM 1290 C CB . PRO A 1 164 ? -65.763 47.922 -27.965 1.00 33.12 ? 165 PRO A CB 1 ATOM 1291 C CG . PRO A 1 164 ? -66.484 46.630 -27.850 1.00 32.38 ? 165 PRO A CG 1 ATOM 1292 C CD . PRO A 1 164 ? -67.454 46.630 -29.000 1.00 34.74 ? 165 PRO A CD 1 ATOM 1293 N N . GLY A 1 165 ? -64.377 46.676 -30.668 1.00 31.06 ? 166 GLY A N 1 ATOM 1294 C CA . GLY A 1 165 ? -63.076 46.091 -31.020 1.00 32.24 ? 166 GLY A CA 1 ATOM 1295 C C . GLY A 1 165 ? -62.601 45.119 -29.920 1.00 33.93 ? 166 GLY A C 1 ATOM 1296 O O . GLY A 1 165 ? -63.143 45.087 -28.808 1.00 31.75 ? 166 GLY A O 1 ATOM 1297 N N . ASN A 1 166 ? -61.644 44.288 -30.291 1.00 30.57 ? 167 ASN A N 1 ATOM 1298 C CA . ASN A 1 166 ? -61.016 43.349 -29.431 1.00 28.08 ? 167 ASN A CA 1 ATOM 1299 C C . ASN A 1 166 ? -61.875 42.257 -28.831 1.00 28.18 ? 167 ASN A C 1 ATOM 1300 O O . ASN A 1 166 ? -61.390 41.508 -27.999 1.00 26.01 ? 167 ASN A O 1 ATOM 1301 C CB . ASN A 1 166 ? -60.295 44.109 -28.361 1.00 27.99 ? 167 ASN A CB 1 ATOM 1302 C CG . ASN A 1 166 ? -59.108 44.858 -28.909 1.00 28.46 ? 167 ASN A CG 1 ATOM 1303 O OD1 . ASN A 1 166 ? -58.561 44.511 -29.963 1.00 28.34 ? 167 ASN A OD1 1 ATOM 1304 N ND2 . ASN A 1 166 ? -58.698 45.883 -28.213 1.00 27.97 ? 167 ASN A ND2 1 ATOM 1305 N N . VAL A 1 167 ? -63.092 42.065 -29.318 1.00 25.49 ? 168 VAL A N 1 ATOM 1306 C CA . VAL A 1 167 ? -63.957 41.153 -28.593 1.00 29.21 ? 168 VAL A CA 1 ATOM 1307 C C . VAL A 1 167 ? -63.489 39.729 -28.641 1.00 29.49 ? 168 VAL A C 1 ATOM 1308 O O . VAL A 1 167 ? -63.723 38.940 -27.669 1.00 31.39 ? 168 VAL A O 1 ATOM 1309 C CB . VAL A 1 167 ? -65.438 41.315 -28.968 1.00 33.41 ? 168 VAL A CB 1 ATOM 1310 C CG1 . VAL A 1 167 ? -65.854 42.768 -28.701 1.00 34.52 ? 168 VAL A CG1 1 ATOM 1311 C CG2 . VAL A 1 167 ? -65.710 40.916 -30.421 1.00 36.75 ? 168 VAL A CG2 1 ATOM 1312 N N . GLY A 1 168 ? -62.735 39.400 -29.702 1.00 26.69 ? 169 GLY A N 1 ATOM 1313 C CA . GLY A 1 168 ? -62.163 38.073 -29.824 1.00 23.62 ? 169 GLY A CA 1 ATOM 1314 C C . GLY A 1 168 ? -61.085 37.843 -28.792 1.00 24.00 ? 169 GLY A C 1 ATOM 1315 O O . GLY A 1 168 ? -60.873 36.713 -28.407 1.00 24.72 ? 169 GLY A O 1 ATOM 1316 N N . LEU A 1 169 ? -60.362 38.885 -28.378 1.00 23.27 ? 170 LEU A N 1 ATOM 1317 C CA . LEU A 1 169 ? -59.386 38.706 -27.321 1.00 26.91 ? 170 LEU A CA 1 ATOM 1318 C C . LEU A 1 169 ? -60.181 38.576 -25.984 1.00 28.82 ? 170 LEU A C 1 ATOM 1319 O O . LEU A 1 169 ? -59.795 37.801 -25.080 1.00 25.71 ? 170 LEU A O 1 ATOM 1320 C CB . LEU A 1 169 ? -58.462 39.888 -27.215 1.00 26.52 ? 170 LEU A CB 1 ATOM 1321 C CG . LEU A 1 169 ? -57.375 39.975 -28.264 1.00 26.75 ? 170 LEU A CG 1 ATOM 1322 C CD1 . LEU A 1 169 ? -56.820 41.378 -28.298 1.00 26.59 ? 170 LEU A CD1 1 ATOM 1323 C CD2 . LEU A 1 169 ? -56.234 38.984 -28.013 1.00 26.66 ? 170 LEU A CD2 1 ATOM 1324 N N . LEU A 1 170 ? -61.277 39.327 -25.867 1.00 25.75 ? 171 LEU A N 1 ATOM 1325 C CA . LEU A 1 170 ? -62.125 39.199 -24.672 1.00 27.50 ? 171 LEU A CA 1 ATOM 1326 C C . LEU A 1 170 ? -62.701 37.760 -24.584 1.00 30.15 ? 171 LEU A C 1 ATOM 1327 O O . LEU A 1 170 ? -62.778 37.258 -23.510 1.00 27.92 ? 171 LEU A O 1 ATOM 1328 C CB . LEU A 1 170 ? -63.209 40.271 -24.624 1.00 26.49 ? 171 LEU A CB 1 ATOM 1329 C CG . LEU A 1 170 ? -62.691 41.701 -24.348 1.00 30.38 ? 171 LEU A CG 1 ATOM 1330 C CD1 . LEU A 1 170 ? -63.826 42.722 -24.305 1.00 29.47 ? 171 LEU A CD1 1 ATOM 1331 C CD2 . LEU A 1 170 ? -61.890 41.844 -23.078 1.00 26.82 ? 171 LEU A CD2 1 ATOM 1332 N N . ASP A 1 171 ? -63.028 37.100 -25.723 1.00 30.48 ? 172 ASP A N 1 ATOM 1333 C CA . ASP A 1 171 ? -63.439 35.716 -25.723 1.00 25.70 ? 172 ASP A CA 1 ATOM 1334 C C . ASP A 1 171 ? -62.330 34.847 -25.138 1.00 27.09 ? 172 ASP A C 1 ATOM 1335 O O . ASP A 1 171 ? -62.571 33.884 -24.394 1.00 27.51 ? 172 ASP A O 1 ATOM 1336 C CB . ASP A 1 171 ? -63.766 35.138 -27.152 1.00 25.22 ? 172 ASP A CB 1 ATOM 1337 C CG . ASP A 1 171 ? -64.915 35.835 -27.876 1.00 28.86 ? 172 ASP A CG 1 ATOM 1338 O OD1 . ASP A 1 171 ? -65.684 36.578 -27.258 1.00 26.87 ? 172 ASP A OD1 1 ATOM 1339 O OD2 . ASP A 1 171 ? -65.052 35.656 -29.143 1.00 29.77 ? 172 ASP A OD2 1 ATOM 1340 N N . GLN A 1 172 ? -61.107 35.065 -25.565 1.00 25.43 ? 173 GLN A N 1 ATOM 1341 C CA . GLN A 1 172 ? -60.061 34.219 -25.064 1.00 26.16 ? 173 GLN A CA 1 ATOM 1342 C C . GLN A 1 172 ? -59.978 34.442 -23.544 1.00 27.13 ? 173 GLN A C 1 ATOM 1343 O O . GLN A 1 172 ? -59.896 33.516 -22.791 1.00 30.64 ? 173 GLN A O 1 ATOM 1344 C CB . GLN A 1 172 ? -58.718 34.539 -25.709 1.00 26.63 ? 173 GLN A CB 1 ATOM 1345 C CG . GLN A 1 172 ? -58.678 34.399 -27.230 1.00 27.14 ? 173 GLN A CG 1 ATOM 1346 C CD . GLN A 1 172 ? -57.421 34.954 -27.849 1.00 27.93 ? 173 GLN A CD 1 ATOM 1347 O OE1 . GLN A 1 172 ? -56.409 35.207 -27.174 1.00 23.30 ? 173 GLN A OE1 1 ATOM 1348 N NE2 . GLN A 1 172 ? -57.453 35.100 -29.180 1.00 33.08 ? 173 GLN A NE2 1 ATOM 1349 N N . ARG A 1 173 ? -60.000 35.691 -23.110 1.00 28.93 ? 174 ARG A N 1 ATOM 1350 C CA . ARG A 1 173 ? -59.910 36.029 -21.694 1.00 28.67 ? 174 ARG A CA 1 ATOM 1351 C C . ARG A 1 173 ? -60.996 35.360 -20.878 1.00 26.06 ? 174 ARG A C 1 ATOM 1352 O O . ARG A 1 173 ? -60.703 34.923 -19.776 1.00 22.58 ? 174 ARG A O 1 ATOM 1353 C CB . ARG A 1 173 ? -59.990 37.526 -21.469 1.00 26.90 ? 174 ARG A CB 1 ATOM 1354 C CG . ARG A 1 173 ? -59.959 37.948 -19.997 1.00 28.10 ? 174 ARG A CG 1 ATOM 1355 C CD . ARG A 1 173 ? -60.273 39.444 -19.844 1.00 27.83 ? 174 ARG A CD 1 ATOM 1356 N NE . ARG A 1 173 ? -59.146 40.217 -20.242 1.00 25.40 ? 174 ARG A NE 1 ATOM 1357 C CZ . ARG A 1 173 ? -59.096 41.543 -20.362 1.00 30.48 ? 174 ARG A CZ 1 ATOM 1358 N NH1 . ARG A 1 173 ? -60.140 42.331 -20.197 1.00 30.90 ? 174 ARG A NH1 1 ATOM 1359 N NH2 . ARG A 1 173 ? -57.928 42.101 -20.649 1.00 32.98 ? 174 ARG A NH2 1 ATOM 1360 N N . MET A 1 174 ? -62.212 35.277 -21.429 1.00 27.04 ? 175 MET A N 1 ATOM 1361 C CA . MET A 1 174 ? -63.337 34.679 -20.713 1.00 30.93 ? 175 MET A CA 1 ATOM 1362 C C . MET A 1 174 ? -63.156 33.188 -20.556 1.00 32.94 ? 175 MET A C 1 ATOM 1363 O O . MET A 1 174 ? -63.560 32.619 -19.528 1.00 34.53 ? 175 MET A O 1 ATOM 1364 C CB . MET A 1 174 ? -64.668 34.938 -21.395 1.00 33.45 ? 175 MET A CB 1 ATOM 1365 C CG . MET A 1 174 ? -65.861 34.515 -20.520 1.00 36.60 ? 175 MET A CG 1 ATOM 1366 S SD . MET A 1 174 ? -67.445 35.116 -21.177 1.00 40.51 ? 175 MET A SD 1 ATOM 1367 C CE . MET A 1 174 ? -67.357 36.727 -20.426 1.00 33.91 ? 175 MET A CE 1 ATOM 1368 N N . ALA A 1 175 ? -62.616 32.544 -21.583 1.00 30.96 ? 176 ALA A N 1 ATOM 1369 C CA . ALA A 1 175 ? -62.308 31.155 -21.474 1.00 32.72 ? 176 ALA A CA 1 ATOM 1370 C C . ALA A 1 175 ? -61.226 30.989 -20.406 1.00 27.84 ? 176 ALA A C 1 ATOM 1371 O O . ALA A 1 175 ? -61.204 30.029 -19.675 1.00 25.13 ? 176 ALA A O 1 ATOM 1372 C CB . ALA A 1 175 ? -61.813 30.595 -22.817 1.00 32.56 ? 176 ALA A CB 1 ATOM 1373 N N . LEU A 1 176 ? -60.280 31.897 -20.372 1.00 27.53 ? 177 LEU A N 1 ATOM 1374 C CA . LEU A 1 176 ? -59.191 31.787 -19.375 1.00 28.27 ? 177 LEU A CA 1 ATOM 1375 C C . LEU A 1 176 ? -59.773 32.042 -17.947 1.00 26.92 ? 177 LEU A C 1 ATOM 1376 O O . LEU A 1 176 ? -59.303 31.464 -17.010 1.00 23.15 ? 177 LEU A O 1 ATOM 1377 C CB . LEU A 1 176 ? -58.062 32.773 -19.636 1.00 27.11 ? 177 LEU A CB 1 ATOM 1378 C CG . LEU A 1 176 ? -57.193 32.644 -20.872 1.00 29.54 ? 177 LEU A CG 1 ATOM 1379 C CD1 . LEU A 1 176 ? -56.162 33.758 -20.847 1.00 31.52 ? 177 LEU A CD1 1 ATOM 1380 C CD2 . LEU A 1 176 ? -56.414 31.352 -20.932 1.00 34.83 ? 177 LEU A CD2 1 ATOM 1381 N N . GLN A 1 177 ? -60.788 32.897 -17.828 1.00 28.03 ? 178 GLN A N 1 ATOM 1382 C CA . GLN A 1 177 ? -61.510 33.095 -16.572 1.00 30.55 ? 178 GLN A CA 1 ATOM 1383 C C . GLN A 1 177 ? -62.190 31.806 -16.154 1.00 29.49 ? 178 GLN A C 1 ATOM 1384 O O . GLN A 1 177 ? -62.156 31.407 -14.982 1.00 31.87 ? 178 GLN A O 1 ATOM 1385 C CB . GLN A 1 177 ? -62.554 34.217 -16.706 1.00 33.05 ? 178 GLN A CB 1 ATOM 1386 C CG . GLN A 1 177 ? -63.335 34.635 -15.444 1.00 30.40 ? 178 GLN A CG 1 ATOM 1387 C CD . GLN A 1 177 ? -62.417 35.214 -14.398 1.00 31.70 ? 178 GLN A CD 1 ATOM 1388 O OE1 . GLN A 1 177 ? -61.904 36.292 -14.581 1.00 32.91 ? 178 GLN A OE1 1 ATOM 1389 N NE2 . GLN A 1 177 ? -62.120 34.438 -13.340 1.00 31.63 ? 178 GLN A NE2 1 ATOM 1390 N N . TRP A 1 178 ? -62.748 31.108 -17.110 1.00 26.14 ? 179 TRP A N 1 ATOM 1391 C CA . TRP A 1 178 ? -63.550 29.949 -16.775 1.00 24.75 ? 179 TRP A CA 1 ATOM 1392 C C . TRP A 1 178 ? -62.616 28.815 -16.394 1.00 25.56 ? 179 TRP A C 1 ATOM 1393 O O . TRP A 1 178 ? -62.914 28.063 -15.522 1.00 25.50 ? 179 TRP A O 1 ATOM 1394 C CB . TRP A 1 178 ? -64.368 29.554 -17.948 1.00 26.50 ? 179 TRP A CB 1 ATOM 1395 C CG . TRP A 1 178 ? -65.371 28.529 -17.720 1.00 29.75 ? 179 TRP A CG 1 ATOM 1396 C CD1 . TRP A 1 178 ? -66.708 28.742 -17.495 1.00 30.75 ? 179 TRP A CD1 1 ATOM 1397 C CD2 . TRP A 1 178 ? -65.171 27.110 -17.670 1.00 28.10 ? 179 TRP A CD2 1 ATOM 1398 N NE1 . TRP A 1 178 ? -67.345 27.537 -17.331 1.00 28.40 ? 179 TRP A NE1 1 ATOM 1399 C CE2 . TRP A 1 178 ? -66.438 26.526 -17.438 1.00 26.81 ? 179 TRP A CE2 1 ATOM 1400 C CE3 . TRP A 1 178 ? -64.059 26.274 -17.851 1.00 29.89 ? 179 TRP A CE3 1 ATOM 1401 C CZ2 . TRP A 1 178 ? -66.618 25.179 -17.332 1.00 26.13 ? 179 TRP A CZ2 1 ATOM 1402 C CZ3 . TRP A 1 178 ? -64.241 24.932 -17.750 1.00 31.12 ? 179 TRP A CZ3 1 ATOM 1403 C CH2 . TRP A 1 178 ? -65.512 24.391 -17.481 1.00 29.16 ? 179 TRP A CH2 1 ATOM 1404 N N . VAL A 1 179 ? -61.467 28.718 -17.009 1.00 26.63 ? 180 VAL A N 1 ATOM 1405 C CA . VAL A 1 179 ? -60.491 27.746 -16.600 1.00 27.82 ? 180 VAL A CA 1 ATOM 1406 C C . VAL A 1 179 ? -60.013 28.086 -15.173 1.00 29.27 ? 180 VAL A C 1 ATOM 1407 O O . VAL A 1 179 ? -59.894 27.249 -14.317 1.00 30.29 ? 180 VAL A O 1 ATOM 1408 C CB . VAL A 1 179 ? -59.268 27.813 -17.563 1.00 29.34 ? 180 VAL A CB 1 ATOM 1409 C CG1 . VAL A 1 179 ? -58.042 27.106 -16.999 1.00 27.49 ? 180 VAL A CG1 1 ATOM 1410 C CG2 . VAL A 1 179 ? -59.619 27.211 -18.905 1.00 30.68 ? 180 VAL A CG2 1 ATOM 1411 N N . HIS A 1 180 ? -59.639 29.319 -14.942 1.00 31.77 ? 181 HIS A N 1 ATOM 1412 C CA . HIS A 1 180 ? -59.253 29.730 -13.625 1.00 31.32 ? 181 HIS A CA 1 ATOM 1413 C C . HIS A 1 180 ? -60.294 29.275 -12.632 1.00 30.21 ? 181 HIS A C 1 ATOM 1414 O O . HIS A 1 180 ? -59.944 28.669 -11.671 1.00 25.67 ? 181 HIS A O 1 ATOM 1415 C CB . HIS A 1 180 ? -59.204 31.222 -13.539 1.00 35.21 ? 181 HIS A CB 1 ATOM 1416 C CG . HIS A 1 180 ? -58.818 31.721 -12.186 1.00 40.99 ? 181 HIS A CG 1 ATOM 1417 N ND1 . HIS A 1 180 ? -59.751 32.145 -11.259 1.00 43.12 ? 181 HIS A ND1 1 ATOM 1418 C CD2 . HIS A 1 180 ? -57.608 31.866 -11.599 1.00 43.09 ? 181 HIS A CD2 1 ATOM 1419 C CE1 . HIS A 1 180 ? -59.130 32.563 -10.170 1.00 43.77 ? 181 HIS A CE1 1 ATOM 1420 N NE2 . HIS A 1 180 ? -57.831 32.413 -10.354 1.00 46.09 ? 181 HIS A NE2 1 ATOM 1421 N N . ASP A 1 181 ? -61.559 29.534 -12.944 1.00 27.61 ? 182 ASP A N 1 ATOM 1422 C CA . ASP A 1 181 ? -62.645 29.310 -12.035 1.00 27.98 ? 182 ASP A CA 1 ATOM 1423 C C . ASP A 1 181 ? -63.080 27.812 -11.865 1.00 34.52 ? 182 ASP A C 1 ATOM 1424 O O . ASP A 1 181 ? -63.674 27.427 -10.821 1.00 34.94 ? 182 ASP A O 1 ATOM 1425 C CB . ASP A 1 181 ? -63.855 30.155 -12.413 1.00 24.65 ? 182 ASP A CB 1 ATOM 1426 C CG . ASP A 1 181 ? -63.677 31.649 -12.150 1.00 26.53 ? 182 ASP A CG 1 ATOM 1427 O OD1 . ASP A 1 181 ? -62.790 32.071 -11.355 1.00 29.51 ? 182 ASP A OD1 1 ATOM 1428 O OD2 . ASP A 1 181 ? -64.459 32.433 -12.751 1.00 31.81 ? 182 ASP A OD2 1 ATOM 1429 N N . ASN A 1 182 ? -62.808 26.975 -12.860 1.00 32.52 ? 183 ASN A N 1 ATOM 1430 C CA . ASN A 1 182 ? -63.361 25.629 -12.867 1.00 29.43 ? 183 ASN A CA 1 ATOM 1431 C C . ASN A 1 182 ? -62.383 24.508 -13.105 1.00 30.76 ? 183 ASN A C 1 ATOM 1432 O O . ASN A 1 182 ? -62.731 23.337 -12.903 1.00 35.58 ? 183 ASN A O 1 ATOM 1433 C CB . ASN A 1 182 ? -64.439 25.534 -13.917 1.00 30.64 ? 183 ASN A CB 1 ATOM 1434 C CG . ASN A 1 182 ? -65.610 26.410 -13.621 1.00 32.57 ? 183 ASN A CG 1 ATOM 1435 O OD1 . ASN A 1 182 ? -66.519 26.055 -12.828 1.00 32.38 ? 183 ASN A OD1 1 ATOM 1436 N ND2 . ASN A 1 182 ? -65.643 27.578 -14.294 1.00 34.14 ? 183 ASN A ND2 1 ATOM 1437 N N . ILE A 1 183 ? -61.161 24.773 -13.536 1.00 29.61 ? 184 ILE A N 1 ATOM 1438 C CA . ILE A 1 183 ? -60.339 23.641 -13.942 1.00 30.70 ? 184 ILE A CA 1 ATOM 1439 C C . ILE A 1 183 ? -60.033 22.722 -12.743 1.00 36.35 ? 184 ILE A C 1 ATOM 1440 O O . ILE A 1 183 ? -59.735 21.506 -12.934 1.00 37.08 ? 184 ILE A O 1 ATOM 1441 C CB . ILE A 1 183 ? -59.059 24.100 -14.654 1.00 30.63 ? 184 ILE A CB 1 ATOM 1442 C CG1 . ILE A 1 183 ? -58.496 23.027 -15.581 1.00 33.58 ? 184 ILE A CG1 1 ATOM 1443 C CG2 . ILE A 1 183 ? -58.005 24.577 -13.680 1.00 29.89 ? 184 ILE A CG2 1 ATOM 1444 C CD1 . ILE A 1 183 ? -59.428 22.694 -16.774 1.00 35.82 ? 184 ILE A CD1 1 ATOM 1445 N N . GLN A 1 184 ? -60.072 23.277 -11.522 1.00 30.86 ? 185 GLN A N 1 ATOM 1446 C CA . GLN A 1 184 ? -59.848 22.449 -10.310 1.00 32.54 ? 185 GLN A CA 1 ATOM 1447 C C . GLN A 1 184 ? -60.758 21.219 -10.352 1.00 28.28 ? 185 GLN A C 1 ATOM 1448 O O . GLN A 1 184 ? -60.339 20.136 -9.989 1.00 26.80 ? 185 GLN A O 1 ATOM 1449 C CB . GLN A 1 184 ? -60.037 23.255 -8.971 1.00 32.04 ? 185 GLN A CB 1 ATOM 1450 C CG . GLN A 1 184 ? -61.457 23.604 -8.709 1.00 33.92 ? 185 GLN A CG 1 ATOM 1451 C CD . GLN A 1 184 ? -61.625 24.726 -7.739 1.00 37.48 ? 185 GLN A CD 1 ATOM 1452 O OE1 . GLN A 1 184 ? -61.325 25.838 -8.078 1.00 37.66 ? 185 GLN A OE1 1 ATOM 1453 N NE2 . GLN A 1 184 ? -62.175 24.449 -6.530 1.00 38.07 ? 185 GLN A NE2 1 ATOM 1454 N N . PHE A 1 185 ? -61.968 21.345 -10.876 1.00 29.20 ? 186 PHE A N 1 ATOM 1455 C CA . PHE A 1 185 ? -62.890 20.191 -10.836 1.00 31.24 ? 186 PHE A CA 1 ATOM 1456 C C . PHE A 1 185 ? -62.537 19.066 -11.809 1.00 36.16 ? 186 PHE A C 1 ATOM 1457 O O . PHE A 1 185 ? -63.103 17.933 -11.705 1.00 38.86 ? 186 PHE A O 1 ATOM 1458 C CB . PHE A 1 185 ? -64.312 20.641 -11.031 1.00 29.34 ? 186 PHE A CB 1 ATOM 1459 C CG . PHE A 1 185 ? -64.700 21.748 -10.102 1.00 32.94 ? 186 PHE A CG 1 ATOM 1460 C CD1 . PHE A 1 185 ? -64.742 21.534 -8.713 1.00 37.82 ? 186 PHE A CD1 1 ATOM 1461 C CD2 . PHE A 1 185 ? -64.988 23.004 -10.575 1.00 32.92 ? 186 PHE A CD2 1 ATOM 1462 C CE1 . PHE A 1 185 ? -65.081 22.566 -7.817 1.00 36.39 ? 186 PHE A CE1 1 ATOM 1463 C CE2 . PHE A 1 185 ? -65.296 24.042 -9.692 1.00 38.25 ? 186 PHE A CE2 1 ATOM 1464 C CZ . PHE A 1 185 ? -65.352 23.815 -8.302 1.00 34.60 ? 186 PHE A CZ 1 ATOM 1465 N N . PHE A 1 186 ? -61.625 19.368 -12.745 1.00 30.69 ? 187 PHE A N 1 ATOM 1466 C CA . PHE A 1 186 ? -61.188 18.379 -13.735 1.00 31.71 ? 187 PHE A CA 1 ATOM 1467 C C . PHE A 1 186 ? -59.832 17.893 -13.321 1.00 30.05 ? 187 PHE A C 1 ATOM 1468 O O . PHE A 1 186 ? -59.207 17.130 -14.008 1.00 27.19 ? 187 PHE A O 1 ATOM 1469 C CB . PHE A 1 186 ? -61.118 18.968 -15.148 1.00 31.29 ? 187 PHE A CB 1 ATOM 1470 C CG . PHE A 1 186 ? -62.444 19.484 -15.663 1.00 29.94 ? 187 PHE A CG 1 ATOM 1471 C CD1 . PHE A 1 186 ? -62.914 20.692 -15.298 1.00 29.66 ? 187 PHE A CD1 1 ATOM 1472 C CD2 . PHE A 1 186 ? -63.202 18.718 -16.545 1.00 35.16 ? 187 PHE A CD2 1 ATOM 1473 C CE1 . PHE A 1 186 ? -64.116 21.159 -15.783 1.00 33.15 ? 187 PHE A CE1 1 ATOM 1474 C CE2 . PHE A 1 186 ? -64.412 19.143 -17.011 1.00 31.93 ? 187 PHE A CE2 1 ATOM 1475 C CZ . PHE A 1 186 ? -64.872 20.387 -16.644 1.00 32.14 ? 187 PHE A CZ 1 ATOM 1476 N N . GLY A 1 187 ? -59.372 18.373 -12.178 1.00 32.51 ? 188 GLY A N 1 ATOM 1477 C CA . GLY A 1 187 ? -58.081 17.958 -11.624 1.00 32.06 ? 188 GLY A CA 1 ATOM 1478 C C . GLY A 1 187 ? -56.896 18.798 -11.999 1.00 31.97 ? 188 GLY A C 1 ATOM 1479 O O . GLY A 1 187 ? -55.713 18.410 -11.759 1.00 30.04 ? 188 GLY A O 1 ATOM 1480 N N . GLY A 1 188 ? -57.188 19.962 -12.568 1.00 34.65 ? 189 GLY A N 1 ATOM 1481 C CA . GLY A 1 188 ? -56.139 20.868 -12.938 1.00 33.95 ? 189 GLY A CA 1 ATOM 1482 C C . GLY A 1 188 ? -55.913 21.834 -11.810 1.00 31.59 ? 189 GLY A C 1 ATOM 1483 O O . GLY A 1 188 ? -56.841 22.226 -11.147 1.00 38.74 ? 189 GLY A O 1 ATOM 1484 N N . ASP A 1 189 ? -54.681 22.264 -11.691 1.00 29.23 ? 190 ASP A N 1 ATOM 1485 C CA . ASP A 1 189 ? -54.246 23.337 -10.792 1.00 28.97 ? 190 ASP A CA 1 ATOM 1486 C C . ASP A 1 189 ? -54.309 24.747 -11.448 1.00 30.16 ? 190 ASP A C 1 ATOM 1487 O O . ASP A 1 189 ? -53.425 25.105 -12.235 1.00 36.70 ? 190 ASP A O 1 ATOM 1488 C CB . ASP A 1 189 ? -52.809 22.989 -10.384 1.00 26.34 ? 190 ASP A CB 1 ATOM 1489 C CG . ASP A 1 189 ? -52.195 23.976 -9.441 1.00 28.54 ? 190 ASP A CG 1 ATOM 1490 O OD1 . ASP A 1 189 ? -52.915 24.867 -8.986 1.00 28.79 ? 190 ASP A OD1 1 ATOM 1491 O OD2 . ASP A 1 189 ? -50.961 23.868 -9.198 1.00 28.78 ? 190 ASP A OD2 1 ATOM 1492 N N . PRO A 1 190 ? -55.286 25.570 -11.076 1.00 27.93 ? 191 PRO A N 1 ATOM 1493 C CA . PRO A 1 190 ? -55.449 26.894 -11.585 1.00 27.19 ? 191 PRO A CA 1 ATOM 1494 C C . PRO A 1 190 ? -54.343 27.861 -11.287 1.00 29.85 ? 191 PRO A C 1 ATOM 1495 O O . PRO A 1 190 ? -54.322 28.953 -11.885 1.00 29.01 ? 191 PRO A O 1 ATOM 1496 C CB . PRO A 1 190 ? -56.733 27.374 -10.907 1.00 28.88 ? 191 PRO A CB 1 ATOM 1497 C CG . PRO A 1 190 ? -56.731 26.635 -9.568 1.00 28.43 ? 191 PRO A CG 1 ATOM 1498 C CD . PRO A 1 190 ? -56.210 25.304 -9.947 1.00 32.64 ? 191 PRO A CD 1 ATOM 1499 N N . LYS A 1 191 ? -53.465 27.504 -10.371 1.00 31.46 ? 192 LYS A N 1 ATOM 1500 C CA . LYS A 1 191 ? -52.296 28.318 -10.029 1.00 36.47 ? 192 LYS A CA 1 ATOM 1501 C C . LYS A 1 191 ? -51.132 27.983 -10.984 1.00 31.67 ? 192 LYS A C 1 ATOM 1502 O O . LYS A 1 191 ? -50.013 28.544 -10.883 1.00 27.56 ? 192 LYS A O 1 ATOM 1503 C CB . LYS A 1 191 ? -51.811 27.983 -8.578 1.00 37.73 ? 192 LYS A CB 1 ATOM 1504 C CG . LYS A 1 191 ? -52.850 27.975 -7.449 1.00 47.43 ? 192 LYS A CG 1 ATOM 1505 C CD . LYS A 1 191 ? -52.262 27.605 -6.020 1.00 48.21 ? 192 LYS A CD 1 ATOM 1506 C CE . LYS A 1 191 ? -51.688 26.180 -5.915 1.00 49.47 ? 192 LYS A CE 1 ATOM 1507 N NZ . LYS A 1 191 ? -52.804 25.198 -6.219 1.00 50.50 ? 192 LYS A NZ 1 ATOM 1508 N N . THR A 1 192 ? -51.330 26.989 -11.820 1.00 28.61 ? 193 THR A N 1 ATOM 1509 C CA . THR A 1 192 ? -50.226 26.579 -12.711 1.00 33.96 ? 193 THR A CA 1 ATOM 1510 C C . THR A 1 192 ? -50.765 26.428 -14.145 1.00 31.24 ? 193 THR A C 1 ATOM 1511 O O . THR A 1 192 ? -50.688 25.334 -14.750 1.00 28.83 ? 193 THR A O 1 ATOM 1512 C CB . THR A 1 192 ? -49.575 25.298 -12.201 1.00 35.03 ? 193 THR A CB 1 ATOM 1513 O OG1 . THR A 1 192 ? -49.231 25.506 -10.842 1.00 42.49 ? 193 THR A OG1 1 ATOM 1514 C CG2 . THR A 1 192 ? -48.324 25.029 -12.896 1.00 33.75 ? 193 THR A CG2 1 ATOM 1515 N N . VAL A 1 193 ? -51.392 27.504 -14.625 1.00 26.78 ? 194 VAL A N 1 ATOM 1516 C CA . VAL A 1 193 ? -51.825 27.554 -16.011 1.00 28.10 ? 194 VAL A CA 1 ATOM 1517 C C . VAL A 1 193 ? -50.800 28.169 -16.954 1.00 27.20 ? 194 VAL A C 1 ATOM 1518 O O . VAL A 1 193 ? -50.356 29.302 -16.764 1.00 32.24 ? 194 VAL A O 1 ATOM 1519 C CB . VAL A 1 193 ? -53.109 28.332 -16.098 1.00 29.37 ? 194 VAL A CB 1 ATOM 1520 C CG1 . VAL A 1 193 ? -53.574 28.385 -17.551 1.00 32.64 ? 194 VAL A CG1 1 ATOM 1521 C CG2 . VAL A 1 193 ? -54.153 27.621 -15.227 1.00 32.48 ? 194 VAL A CG2 1 ATOM 1522 N N . THR A 1 194 ? -50.386 27.421 -17.955 1.00 28.63 ? 195 THR A N 1 ATOM 1523 C CA . THR A 1 194 ? -49.588 27.973 -19.046 1.00 25.49 ? 195 THR A CA 1 ATOM 1524 C C . THR A 1 194 ? -50.482 28.266 -20.276 1.00 27.05 ? 195 THR A C 1 ATOM 1525 O O . THR A 1 194 ? -51.164 27.352 -20.753 1.00 28.57 ? 195 THR A O 1 ATOM 1526 C CB . THR A 1 194 ? -48.456 27.052 -19.405 1.00 26.98 ? 195 THR A CB 1 ATOM 1527 O OG1 . THR A 1 194 ? -47.519 27.050 -18.330 1.00 29.30 ? 195 THR A OG1 1 ATOM 1528 C CG2 . THR A 1 194 ? -47.685 27.607 -20.630 1.00 28.42 ? 195 THR A CG2 1 ATOM 1529 N N . ILE A 1 195 ? -50.561 29.534 -20.735 1.00 24.22 ? 196 ILE A N 1 ATOM 1530 C CA . ILE A 1 195 ? -51.127 29.781 -22.052 1.00 25.37 ? 196 ILE A CA 1 ATOM 1531 C C . ILE A 1 195 ? -50.095 29.562 -23.194 1.00 26.24 ? 196 ILE A C 1 ATOM 1532 O O . ILE A 1 195 ? -48.930 29.943 -23.089 1.00 23.77 ? 196 ILE A O 1 ATOM 1533 C CB . ILE A 1 195 ? -51.857 31.099 -22.171 1.00 26.37 ? 196 ILE A CB 1 ATOM 1534 C CG1 . ILE A 1 195 ? -50.934 32.258 -21.962 1.00 27.49 ? 196 ILE A CG1 1 ATOM 1535 C CG2 . ILE A 1 195 ? -53.000 31.113 -21.165 1.00 29.76 ? 196 ILE A CG2 1 ATOM 1536 C CD1 . ILE A 1 195 ? -51.599 33.595 -22.140 1.00 28.02 ? 196 ILE A CD1 1 ATOM 1537 N N . PHE A 1 196 ? -50.513 28.854 -24.245 1.00 27.37 ? 197 PHE A N 1 ATOM 1538 C CA . PHE A 1 196 ? -49.621 28.644 -25.404 1.00 26.37 ? 197 PHE A CA 1 ATOM 1539 C C . PHE A 1 196 ? -50.350 28.779 -26.713 1.00 25.65 ? 197 PHE A C 1 ATOM 1540 O O . PHE A 1 196 ? -51.531 28.560 -26.763 1.00 26.05 ? 197 PHE A O 1 ATOM 1541 C CB . PHE A 1 196 ? -48.778 27.406 -25.280 1.00 26.05 ? 197 PHE A CB 1 ATOM 1542 C CG . PHE A 1 196 ? -49.469 26.109 -25.529 1.00 26.47 ? 197 PHE A CG 1 ATOM 1543 C CD1 . PHE A 1 196 ? -50.613 25.760 -24.851 1.00 27.91 ? 197 PHE A CD1 1 ATOM 1544 C CD2 . PHE A 1 196 ? -48.836 25.132 -26.341 1.00 25.09 ? 197 PHE A CD2 1 ATOM 1545 C CE1 . PHE A 1 196 ? -51.190 24.494 -25.039 1.00 27.02 ? 197 PHE A CE1 1 ATOM 1546 C CE2 . PHE A 1 196 ? -49.422 23.886 -26.573 1.00 26.62 ? 197 PHE A CE2 1 ATOM 1547 C CZ . PHE A 1 196 ? -50.603 23.562 -25.896 1.00 28.01 ? 197 PHE A CZ 1 ATOM 1548 N N . GLY A 1 197 ? -49.677 29.245 -27.754 1.00 27.16 ? 198 GLY A N 1 ATOM 1549 C CA . GLY A 1 197 ? -50.360 29.494 -29.033 1.00 26.42 ? 198 GLY A CA 1 ATOM 1550 C C . GLY A 1 197 ? -49.372 29.759 -30.152 1.00 26.89 ? 198 GLY A C 1 ATOM 1551 O O . GLY A 1 197 ? -48.209 30.110 -29.897 1.00 24.82 ? 198 GLY A O 1 ATOM 1552 N N . GLU A 1 198 ? -49.856 29.568 -31.378 1.00 25.91 ? 199 GLU A N 1 ATOM 1553 C CA . GLU A 1 198 ? -49.055 29.738 -32.587 1.00 26.96 ? 199 GLU A CA 1 ATOM 1554 C C . GLU A 1 198 ? -49.491 30.869 -33.468 1.00 23.83 ? 199 GLU A C 1 ATOM 1555 O O . GLU A 1 198 ? -50.664 31.082 -33.684 1.00 23.01 ? 199 GLU A O 1 ATOM 1556 C CB . GLU A 1 198 ? -48.922 28.436 -33.369 1.00 28.20 ? 199 GLU A CB 1 ATOM 1557 C CG . GLU A 1 198 ? -47.873 28.503 -34.478 1.00 26.91 ? 199 GLU A CG 1 ATOM 1558 C CD . GLU A 1 198 ? -48.515 28.855 -35.812 1.00 28.28 ? 199 GLU A CD 1 ATOM 1559 O OE1 . GLU A 1 198 ? -49.782 28.879 -35.887 1.00 29.57 ? 199 GLU A OE1 1 ATOM 1560 O OE2 . GLU A 1 198 ? -47.773 29.105 -36.798 1.00 31.63 ? 199 GLU A OE2 1 ATOM 1561 N N . SER A 1 199 ? -48.508 31.628 -33.932 1.00 25.24 ? 200 SER A N 1 ATOM 1562 C CA . SER A 1 199 ? -48.744 32.722 -34.847 1.00 25.88 ? 200 SER A CA 1 ATOM 1563 C C . SER A 1 199 ? -49.730 33.760 -34.214 1.00 23.71 ? 200 SER A C 1 ATOM 1564 O O . SER A 1 199 ? -49.412 34.340 -33.206 1.00 27.76 ? 200 SER A O 1 ATOM 1565 C CB . SER A 1 199 ? -49.209 32.163 -36.222 1.00 26.59 ? 200 SER A CB 1 ATOM 1566 O OG . SER A 1 199 ? -49.333 33.256 -37.163 1.00 31.94 ? 200 SER A OG 1 ATOM 1567 N N . ALA A 1 200 ? -50.909 34.005 -34.766 1.00 21.35 ? 201 ALA A N 1 ATOM 1568 C CA . ALA A 1 200 ? -51.849 34.917 -34.130 1.00 22.40 ? 201 ALA A CA 1 ATOM 1569 C C . ALA A 1 200 ? -52.197 34.465 -32.670 1.00 24.15 ? 201 ALA A C 1 ATOM 1570 O O . ALA A 1 200 ? -52.625 35.266 -31.854 1.00 25.80 ? 201 ALA A O 1 ATOM 1571 C CB . ALA A 1 200 ? -53.143 35.008 -34.952 1.00 20.21 ? 201 ALA A CB 1 ATOM 1572 N N . GLY A 1 201 ? -52.105 33.179 -32.414 1.00 25.42 ? 202 GLY A N 1 ATOM 1573 C CA . GLY A 1 201 ? -52.284 32.625 -31.077 1.00 27.15 ? 202 GLY A CA 1 ATOM 1574 C C . GLY A 1 201 ? -51.064 32.965 -30.252 1.00 27.11 ? 202 GLY A C 1 ATOM 1575 O O . GLY A 1 201 ? -51.191 33.279 -29.099 1.00 23.35 ? 202 GLY A O 1 ATOM 1576 N N . GLY A 1 202 ? -49.867 32.894 -30.838 1.00 25.85 ? 203 GLY A N 1 ATOM 1577 C CA . GLY A 1 202 ? -48.693 33.381 -30.148 1.00 25.26 ? 203 GLY A CA 1 ATOM 1578 C C . GLY A 1 202 ? -48.784 34.878 -29.807 1.00 27.14 ? 203 GLY A C 1 ATOM 1579 O O . GLY A 1 202 ? -48.370 35.315 -28.736 1.00 27.13 ? 203 GLY A O 1 ATOM 1580 N N . ALA A 1 203 ? -49.301 35.674 -30.746 1.00 24.41 ? 204 ALA A N 1 ATOM 1581 C CA . ALA A 1 203 ? -49.401 37.064 -30.497 1.00 25.73 ? 204 ALA A CA 1 ATOM 1582 C C . ALA A 1 203 ? -50.481 37.337 -29.383 1.00 23.83 ? 204 ALA A C 1 ATOM 1583 O O . ALA A 1 203 ? -50.386 38.282 -28.574 1.00 21.46 ? 204 ALA A O 1 ATOM 1584 C CB . ALA A 1 203 ? -49.676 37.855 -31.809 1.00 22.68 ? 204 ALA A CB 1 ATOM 1585 N N . SER A 1 204 ? -51.565 36.606 -29.478 1.00 22.99 ? 205 SER A N 1 ATOM 1586 C CA . SER A 1 204 ? -52.639 36.688 -28.495 1.00 24.53 ? 205 SER A CA 1 ATOM 1587 C C . SER A 1 204 ? -52.012 36.458 -27.077 1.00 24.53 ? 205 SER A C 1 ATOM 1588 O O . SER A 1 204 ? -52.300 37.199 -26.135 1.00 22.39 ? 205 SER A O 1 ATOM 1589 C CB . SER A 1 204 ? -53.684 35.583 -28.765 1.00 25.10 ? 205 SER A CB 1 ATOM 1590 O OG . SER A 1 204 ? -54.595 35.893 -29.840 1.00 24.57 ? 205 SER A OG 1 ATOM 1591 N N . VAL A 1 205 ? -51.201 35.407 -26.954 1.00 21.51 ? 206 VAL A N 1 ATOM 1592 C CA . VAL A 1 205 ? -50.540 35.067 -25.688 1.00 24.41 ? 206 VAL A CA 1 ATOM 1593 C C . VAL A 1 205 ? -49.788 36.304 -25.171 1.00 24.89 ? 206 VAL A C 1 ATOM 1594 O O . VAL A 1 205 ? -50.038 36.787 -24.061 1.00 28.55 ? 206 VAL A O 1 ATOM 1595 C CB . VAL A 1 205 ? -49.627 33.860 -25.852 1.00 22.73 ? 206 VAL A CB 1 ATOM 1596 C CG1 . VAL A 1 205 ? -48.682 33.788 -24.702 1.00 24.75 ? 206 VAL A CG1 1 ATOM 1597 C CG2 . VAL A 1 205 ? -50.442 32.554 -25.995 1.00 23.64 ? 206 VAL A CG2 1 ATOM 1598 N N . GLY A 1 206 ? -48.991 36.893 -26.031 1.00 22.00 ? 207 GLY A N 1 ATOM 1599 C CA . GLY A 1 206 ? -48.239 38.118 -25.700 1.00 23.54 ? 207 GLY A CA 1 ATOM 1600 C C . GLY A 1 206 ? -49.141 39.267 -25.336 1.00 21.38 ? 207 GLY A C 1 ATOM 1601 O O . GLY A 1 206 ? -48.773 40.112 -24.544 1.00 20.70 ? 207 GLY A O 1 ATOM 1602 N N . MET A 1 207 ? -50.323 39.267 -25.911 1.00 20.64 ? 208 MET A N 1 ATOM 1603 C CA . MET A 1 207 ? -51.273 40.275 -25.635 1.00 23.43 ? 208 MET A CA 1 ATOM 1604 C C . MET A 1 207 ? -51.914 40.122 -24.230 1.00 25.68 ? 208 MET A C 1 ATOM 1605 O O . MET A 1 207 ? -52.231 41.125 -23.604 1.00 29.09 ? 208 MET A O 1 ATOM 1606 C CB . MET A 1 207 ? -52.331 40.347 -26.723 1.00 23.19 ? 208 MET A CB 1 ATOM 1607 C CG . MET A 1 207 ? -51.829 41.026 -28.022 1.00 26.87 ? 208 MET A CG 1 ATOM 1608 S SD . MET A 1 207 ? -52.954 40.813 -29.464 1.00 25.27 ? 208 MET A SD 1 ATOM 1609 C CE . MET A 1 207 ? -52.004 41.760 -30.647 1.00 26.62 ? 208 MET A CE 1 ATOM 1610 N N . HIS A 1 208 ? -52.083 38.896 -23.764 1.00 23.83 ? 209 HIS A N 1 ATOM 1611 C CA . HIS A 1 208 ? -52.619 38.643 -22.461 1.00 25.80 ? 209 HIS A CA 1 ATOM 1612 C C . HIS A 1 208 ? -51.540 38.911 -21.403 1.00 26.93 ? 209 HIS A C 1 ATOM 1613 O O . HIS A 1 208 ? -51.872 39.336 -20.320 1.00 27.21 ? 209 HIS A O 1 ATOM 1614 C CB . HIS A 1 208 ? -53.148 37.243 -22.337 1.00 24.38 ? 209 HIS A CB 1 ATOM 1615 C CG . HIS A 1 208 ? -54.387 37.019 -23.156 1.00 26.07 ? 209 HIS A CG 1 ATOM 1616 N ND1 . HIS A 1 208 ? -55.522 37.772 -22.988 1.00 25.43 ? 209 HIS A ND1 1 ATOM 1617 C CD2 . HIS A 1 208 ? -54.644 36.175 -24.187 1.00 23.88 ? 209 HIS A CD2 1 ATOM 1618 C CE1 . HIS A 1 208 ? -56.460 37.355 -23.811 1.00 25.32 ? 209 HIS A CE1 1 ATOM 1619 N NE2 . HIS A 1 208 ? -55.946 36.400 -24.568 1.00 24.76 ? 209 HIS A NE2 1 ATOM 1620 N N . ILE A 1 209 ? -50.276 38.748 -21.766 1.00 26.50 ? 210 ILE A N 1 ATOM 1621 C CA . ILE A 1 209 ? -49.151 39.167 -20.918 1.00 25.89 ? 210 ILE A CA 1 ATOM 1622 C C . ILE A 1 209 ? -49.116 40.659 -20.714 1.00 27.64 ? 210 ILE A C 1 ATOM 1623 O O . ILE A 1 209 ? -48.727 41.111 -19.644 1.00 27.46 ? 210 ILE A O 1 ATOM 1624 C CB . ILE A 1 209 ? -47.838 38.759 -21.551 1.00 26.33 ? 210 ILE A CB 1 ATOM 1625 C CG1 . ILE A 1 209 ? -47.721 37.263 -21.483 1.00 25.31 ? 210 ILE A CG1 1 ATOM 1626 C CG2 . ILE A 1 209 ? -46.670 39.471 -20.891 1.00 30.46 ? 210 ILE A CG2 1 ATOM 1627 C CD1 . ILE A 1 209 ? -46.487 36.702 -22.123 1.00 26.97 ? 210 ILE A CD1 1 ATOM 1628 N N . LEU A 1 210 ? -49.550 41.436 -21.712 1.00 26.63 ? 211 LEU A N 1 ATOM 1629 C CA . LEU A 1 210 ? -49.410 42.870 -21.597 1.00 26.00 ? 211 LEU A CA 1 ATOM 1630 C C . LEU A 1 210 ? -50.637 43.493 -20.951 1.00 27.03 ? 211 LEU A C 1 ATOM 1631 O O . LEU A 1 210 ? -50.532 44.459 -20.157 1.00 25.99 ? 211 LEU A O 1 ATOM 1632 C CB . LEU A 1 210 ? -49.228 43.482 -22.975 1.00 27.23 ? 211 LEU A CB 1 ATOM 1633 C CG . LEU A 1 210 ? -47.827 43.510 -23.592 1.00 32.78 ? 211 LEU A CG 1 ATOM 1634 C CD1 . LEU A 1 210 ? -48.082 43.620 -25.065 1.00 35.69 ? 211 LEU A CD1 1 ATOM 1635 C CD2 . LEU A 1 210 ? -47.014 44.723 -23.162 1.00 36.24 ? 211 LEU A CD2 1 ATOM 1636 N N . SER A 1 211 ? -51.808 43.003 -21.346 1.00 23.78 ? 212 SER A N 1 ATOM 1637 C CA . SER A 1 211 ? -53.069 43.515 -20.863 1.00 26.29 ? 212 SER A CA 1 ATOM 1638 C C . SER A 1 211 ? -53.360 43.234 -19.358 1.00 29.29 ? 212 SER A C 1 ATOM 1639 O O . SER A 1 211 ? -53.553 42.047 -18.982 1.00 29.49 ? 212 SER A O 1 ATOM 1640 C CB . SER A 1 211 ? -54.200 42.868 -21.626 1.00 26.19 ? 212 SER A CB 1 ATOM 1641 O OG . SER A 1 211 ? -55.423 43.458 -21.254 1.00 23.76 ? 212 SER A OG 1 ATOM 1642 N N . PRO A 1 212 ? -53.434 44.314 -18.533 1.00 32.98 ? 213 PRO A N 1 ATOM 1643 C CA . PRO A 1 212 ? -53.775 44.291 -17.080 1.00 31.70 ? 213 PRO A CA 1 ATOM 1644 C C . PRO A 1 212 ? -54.967 43.434 -16.792 1.00 29.30 ? 213 PRO A C 1 ATOM 1645 O O . PRO A 1 212 ? -54.912 42.585 -15.928 1.00 24.94 ? 213 PRO A O 1 ATOM 1646 C CB . PRO A 1 212 ? -54.072 45.777 -16.769 1.00 32.19 ? 213 PRO A CB 1 ATOM 1647 C CG . PRO A 1 212 ? -53.239 46.533 -17.754 1.00 33.15 ? 213 PRO A CG 1 ATOM 1648 C CD . PRO A 1 212 ? -53.311 45.716 -19.014 1.00 32.89 ? 213 PRO A CD 1 ATOM 1649 N N . GLY A 1 213 ? -56.008 43.523 -17.625 1.00 29.20 ? 214 GLY A N 1 ATOM 1650 C CA . GLY A 1 213 ? -57.190 42.664 -17.394 1.00 27.00 ? 214 GLY A CA 1 ATOM 1651 C C . GLY A 1 213 ? -57.037 41.160 -17.601 1.00 29.29 ? 214 GLY A C 1 ATOM 1652 O O . GLY A 1 213 ? -57.965 40.418 -17.225 1.00 32.67 ? 214 GLY A O 1 ATOM 1653 N N . SER A 1 214 ? -55.922 40.697 -18.214 1.00 25.65 ? 215 SER A N 1 ATOM 1654 C CA . SER A 1 214 ? -55.688 39.269 -18.453 1.00 25.66 ? 215 SER A CA 1 ATOM 1655 C C . SER A 1 214 ? -54.590 38.666 -17.605 1.00 25.03 ? 215 SER A C 1 ATOM 1656 O O . SER A 1 214 ? -54.570 37.457 -17.390 1.00 24.69 ? 215 SER A O 1 ATOM 1657 C CB . SER A 1 214 ? -55.324 38.981 -19.984 1.00 26.01 ? 215 SER A CB 1 ATOM 1658 O OG . SER A 1 214 ? -56.410 39.282 -20.868 1.00 24.38 ? 215 SER A OG 1 ATOM 1659 N N . ARG A 1 215 ? -53.625 39.471 -17.200 1.00 26.08 ? 216 ARG A N 1 ATOM 1660 C CA . ARG A 1 215 ? -52.430 38.920 -16.535 1.00 27.75 ? 216 ARG A CA 1 ATOM 1661 C C . ARG A 1 215 ? -52.674 37.954 -15.396 1.00 27.97 ? 216 ARG A C 1 ATOM 1662 O O . ARG A 1 215 ? -51.821 37.111 -15.129 1.00 26.05 ? 216 ARG A O 1 ATOM 1663 C CB . ARG A 1 215 ? -51.571 40.021 -15.873 1.00 30.00 ? 216 ARG A CB 1 ATOM 1664 C CG . ARG A 1 215 ? -51.324 41.226 -16.735 1.00 33.94 ? 216 ARG A CG 1 ATOM 1665 C CD . ARG A 1 215 ? -50.297 42.172 -16.173 1.00 33.45 ? 216 ARG A CD 1 ATOM 1666 N NE . ARG A 1 215 ? -50.179 43.294 -17.093 1.00 31.04 ? 216 ARG A NE 1 ATOM 1667 C CZ . ARG A 1 215 ? -49.670 44.463 -16.789 1.00 33.57 ? 216 ARG A CZ 1 ATOM 1668 N NH1 . ARG A 1 215 ? -49.179 44.691 -15.555 1.00 33.45 ? 216 ARG A NH1 1 ATOM 1669 N NH2 . ARG A 1 215 ? -49.622 45.405 -17.727 1.00 34.29 ? 216 ARG A NH2 1 ATOM 1670 N N . ASP A 1 216 ? -53.727 38.168 -14.613 1.00 28.00 ? 217 ASP A N 1 ATOM 1671 C CA . ASP A 1 216 ? -53.785 37.429 -13.339 1.00 31.18 ? 217 ASP A CA 1 ATOM 1672 C C . ASP A 1 216 ? -54.330 36.052 -13.574 1.00 34.07 ? 217 ASP A C 1 ATOM 1673 O O . ASP A 1 216 ? -54.396 35.287 -12.629 1.00 37.02 ? 217 ASP A O 1 ATOM 1674 C CB . ASP A 1 216 ? -54.719 38.113 -12.313 1.00 31.48 ? 217 ASP A CB 1 ATOM 1675 C CG . ASP A 1 216 ? -54.284 39.519 -11.948 1.00 30.38 ? 217 ASP A CG 1 ATOM 1676 O OD1 . ASP A 1 216 ? -53.222 39.972 -12.380 1.00 33.28 ? 217 ASP A OD1 1 ATOM 1677 O OD2 . ASP A 1 216 ? -55.062 40.221 -11.304 1.00 30.93 ? 217 ASP A OD2 1 ATOM 1678 N N . LEU A 1 217 ? -54.862 35.789 -14.782 1.00 28.44 ? 218 LEU A N 1 ATOM 1679 C CA . LEU A 1 217 ? -55.548 34.573 -15.058 1.00 25.75 ? 218 LEU A CA 1 ATOM 1680 C C . LEU A 1 217 ? -54.620 33.465 -15.529 1.00 26.41 ? 218 LEU A C 1 ATOM 1681 O O . LEU A 1 217 ? -55.088 32.405 -15.831 1.00 32.04 ? 218 LEU A O 1 ATOM 1682 C CB . LEU A 1 217 ? -56.603 34.774 -16.114 1.00 28.11 ? 218 LEU A CB 1 ATOM 1683 C CG . LEU A 1 217 ? -57.660 35.837 -15.844 1.00 29.49 ? 218 LEU A CG 1 ATOM 1684 C CD1 . LEU A 1 217 ? -58.599 35.957 -17.033 1.00 30.39 ? 218 LEU A CD1 1 ATOM 1685 C CD2 . LEU A 1 217 ? -58.460 35.552 -14.589 1.00 27.68 ? 218 LEU A CD2 1 ATOM 1686 N N . PHE A 1 218 ? -53.312 33.631 -15.536 1.00 24.30 ? 219 PHE A N 1 ATOM 1687 C CA . PHE A 1 218 ? -52.524 32.477 -15.941 1.00 26.06 ? 219 PHE A CA 1 ATOM 1688 C C . PHE A 1 218 ? -51.189 32.644 -15.302 1.00 25.00 ? 219 PHE A C 1 ATOM 1689 O O . PHE A 1 218 ? -50.887 33.696 -14.843 1.00 26.01 ? 219 PHE A O 1 ATOM 1690 C CB . PHE A 1 218 ? -52.415 32.398 -17.510 1.00 27.50 ? 219 PHE A CB 1 ATOM 1691 C CG . PHE A 1 218 ? -51.771 33.588 -18.123 1.00 24.68 ? 219 PHE A CG 1 ATOM 1692 C CD1 . PHE A 1 218 ? -52.519 34.713 -18.415 1.00 28.62 ? 219 PHE A CD1 1 ATOM 1693 C CD2 . PHE A 1 218 ? -50.450 33.611 -18.371 1.00 25.66 ? 219 PHE A CD2 1 ATOM 1694 C CE1 . PHE A 1 218 ? -51.915 35.855 -18.946 1.00 27.62 ? 219 PHE A CE1 1 ATOM 1695 C CE2 . PHE A 1 218 ? -49.834 34.755 -18.934 1.00 29.77 ? 219 PHE A CE2 1 ATOM 1696 C CZ . PHE A 1 218 ? -50.558 35.879 -19.190 1.00 25.44 ? 219 PHE A CZ 1 ATOM 1697 N N . ARG A 1 219 ? -50.345 31.626 -15.320 1.00 25.79 ? 220 ARG A N 1 ATOM 1698 C CA . ARG A 1 219 ? -49.101 31.709 -14.598 1.00 25.40 ? 220 ARG A CA 1 ATOM 1699 C C . ARG A 1 219 ? -47.941 32.010 -15.526 1.00 26.72 ? 220 ARG A C 1 ATOM 1700 O O . ARG A 1 219 ? -47.000 32.799 -15.212 1.00 26.21 ? 220 ARG A O 1 ATOM 1701 C CB . ARG A 1 219 ? -48.879 30.323 -13.942 1.00 28.58 ? 220 ARG A CB 1 ATOM 1702 C CG . ARG A 1 219 ? -47.521 30.062 -13.292 1.00 30.43 ? 220 ARG A CG 1 ATOM 1703 C CD . ARG A 1 219 ? -47.383 30.907 -12.055 1.00 37.52 ? 220 ARG A CD 1 ATOM 1704 N NE . ARG A 1 219 ? -46.315 30.439 -11.138 1.00 48.75 ? 220 ARG A NE 1 ATOM 1705 C CZ . ARG A 1 219 ? -46.463 29.539 -10.156 1.00 46.25 ? 220 ARG A CZ 1 ATOM 1706 N NH1 . ARG A 1 219 ? -47.620 28.930 -9.919 1.00 48.95 ? 220 ARG A NH1 1 ATOM 1707 N NH2 . ARG A 1 219 ? -45.438 29.265 -9.385 1.00 48.26 ? 220 ARG A NH2 1 ATOM 1708 N N . ARG A 1 220 ? -47.924 31.267 -16.625 1.00 26.85 ? 221 ARG A N 1 ATOM 1709 C CA . ARG A 1 220 ? -46.845 31.434 -17.601 1.00 27.80 ? 221 ARG A CA 1 ATOM 1710 C C . ARG A 1 220 ? -47.228 31.175 -19.065 1.00 25.18 ? 221 ARG A C 1 ATOM 1711 O O . ARG A 1 220 ? -48.401 30.952 -19.342 1.00 22.88 ? 221 ARG A O 1 ATOM 1712 C CB . ARG A 1 220 ? -45.583 30.777 -17.139 1.00 28.33 ? 221 ARG A CB 1 ATOM 1713 C CG . ARG A 1 220 ? -45.528 29.302 -16.948 1.00 28.72 ? 221 ARG A CG 1 ATOM 1714 C CD . ARG A 1 220 ? -44.217 28.978 -16.160 1.00 30.46 ? 221 ARG A CD 1 ATOM 1715 N NE . ARG A 1 220 ? -44.591 27.928 -15.277 1.00 44.13 ? 221 ARG A NE 1 ATOM 1716 C CZ . ARG A 1 220 ? -44.399 27.840 -13.980 1.00 40.88 ? 221 ARG A CZ 1 ATOM 1717 N NH1 . ARG A 1 220 ? -43.656 28.670 -13.308 1.00 36.27 ? 221 ARG A NH1 1 ATOM 1718 N NH2 . ARG A 1 220 ? -44.993 26.834 -13.380 1.00 46.88 ? 221 ARG A NH2 1 ATOM 1719 N N . ALA A 1 221 ? -46.296 31.410 -19.990 1.00 24.95 ? 222 ALA A N 1 ATOM 1720 C CA . ALA A 1 221 ? -46.638 31.551 -21.434 1.00 25.59 ? 222 ALA A CA 1 ATOM 1721 C C . ALA A 1 221 ? -45.608 31.025 -22.374 1.00 24.90 ? 222 ALA A C 1 ATOM 1722 O O . ALA A 1 221 ? -44.385 31.110 -22.128 1.00 24.18 ? 222 ALA A O 1 ATOM 1723 C CB . ALA A 1 221 ? -46.961 32.979 -21.806 1.00 25.07 ? 222 ALA A CB 1 ATOM 1724 N N . ILE A 1 222 ? -46.151 30.421 -23.427 1.00 26.62 ? 223 ILE A N 1 ATOM 1725 C CA . ILE A 1 222 ? -45.402 29.936 -24.582 1.00 27.32 ? 223 ILE A CA 1 ATOM 1726 C C . ILE A 1 222 ? -45.930 30.603 -25.879 1.00 24.38 ? 223 ILE A C 1 ATOM 1727 O O . ILE A 1 222 ? -47.136 30.545 -26.162 1.00 23.30 ? 223 ILE A O 1 ATOM 1728 C CB . ILE A 1 222 ? -45.529 28.437 -24.657 1.00 27.99 ? 223 ILE A CB 1 ATOM 1729 C CG1 . ILE A 1 222 ? -44.901 27.781 -23.390 1.00 29.65 ? 223 ILE A CG1 1 ATOM 1730 C CG2 . ILE A 1 222 ? -44.811 27.899 -25.904 1.00 27.37 ? 223 ILE A CG2 1 ATOM 1731 C CD1 . ILE A 1 222 ? -45.059 26.255 -23.386 1.00 29.06 ? 223 ILE A CD1 1 ATOM 1732 N N . LEU A 1 223 ? -45.027 31.228 -26.615 1.00 21.06 ? 224 LEU A N 1 ATOM 1733 C CA . LEU A 1 223 ? -45.317 31.926 -27.878 1.00 22.90 ? 224 LEU A CA 1 ATOM 1734 C C . LEU A 1 223 ? -44.564 31.247 -29.038 1.00 23.76 ? 224 LEU A C 1 ATOM 1735 O O . LEU A 1 223 ? -43.349 31.242 -29.087 1.00 22.47 ? 224 LEU A O 1 ATOM 1736 C CB . LEU A 1 223 ? -44.870 33.385 -27.804 1.00 22.95 ? 224 LEU A CB 1 ATOM 1737 C CG . LEU A 1 223 ? -45.586 34.268 -26.780 1.00 24.96 ? 224 LEU A CG 1 ATOM 1738 C CD1 . LEU A 1 223 ? -44.951 34.140 -25.391 1.00 25.41 ? 224 LEU A CD1 1 ATOM 1739 C CD2 . LEU A 1 223 ? -45.576 35.717 -27.226 1.00 28.46 ? 224 LEU A CD2 1 ATOM 1740 N N . GLN A 1 224 ? -45.291 30.701 -29.989 1.00 25.30 ? 225 GLN A N 1 ATOM 1741 C CA . GLN A 1 224 ? -44.693 29.953 -31.132 1.00 25.12 ? 225 GLN A CA 1 ATOM 1742 C C . GLN A 1 224 ? -44.903 30.831 -32.400 1.00 24.48 ? 225 GLN A C 1 ATOM 1743 O O . GLN A 1 224 ? -46.038 31.036 -32.782 1.00 20.48 ? 225 GLN A O 1 ATOM 1744 C CB . GLN A 1 224 ? -45.468 28.646 -31.270 1.00 26.05 ? 225 GLN A CB 1 ATOM 1745 C CG . GLN A 1 224 ? -45.043 27.608 -30.213 1.00 29.63 ? 225 GLN A CG 1 ATOM 1746 C CD . GLN A 1 224 ? -45.983 26.407 -30.115 1.00 28.81 ? 225 GLN A CD 1 ATOM 1747 O OE1 . GLN A 1 224 ? -46.414 26.026 -29.047 1.00 26.88 ? 225 GLN A OE1 1 ATOM 1748 N NE2 . GLN A 1 224 ? -46.364 25.861 -31.252 1.00 31.44 ? 225 GLN A NE2 1 ATOM 1749 N N . SER A 1 225 ? -43.846 31.452 -32.949 1.00 23.05 ? 226 SER A N 1 ATOM 1750 C CA . SER A 1 225 ? -43.946 32.114 -34.247 1.00 24.30 ? 226 SER A CA 1 ATOM 1751 C C . SER A 1 225 ? -44.907 33.267 -34.179 1.00 24.70 ? 226 SER A C 1 ATOM 1752 O O . SER A 1 225 ? -45.745 33.450 -35.053 1.00 28.59 ? 226 SER A O 1 ATOM 1753 C CB . SER A 1 225 ? -44.426 31.094 -35.362 1.00 26.79 ? 226 SER A CB 1 ATOM 1754 O OG . SER A 1 225 ? -43.498 29.988 -35.566 1.00 22.25 ? 226 SER A OG 1 ATOM 1755 N N . GLY A 1 226 ? -44.854 34.033 -33.110 1.00 27.52 ? 227 GLY A N 1 ATOM 1756 C CA . GLY A 1 226 ? -45.844 35.113 -32.925 1.00 24.29 ? 227 GLY A CA 1 ATOM 1757 C C . GLY A 1 226 ? -45.469 35.946 -31.735 1.00 25.32 ? 227 GLY A C 1 ATOM 1758 O O . GLY A 1 226 ? -44.892 35.469 -30.790 1.00 27.90 ? 227 GLY A O 1 ATOM 1759 N N . SER A 1 227 ? -45.750 37.236 -31.857 1.00 29.12 ? 228 SER A N 1 ATOM 1760 C CA . SER A 1 227 ? -45.417 38.215 -30.844 1.00 26.64 ? 228 SER A CA 1 ATOM 1761 C C . SER A 1 227 ? -46.467 39.303 -30.934 1.00 27.92 ? 228 SER A C 1 ATOM 1762 O O . SER A 1 227 ? -47.044 39.536 -31.996 1.00 23.60 ? 228 SER A O 1 ATOM 1763 C CB . SER A 1 227 ? -44.026 38.797 -31.091 1.00 28.14 ? 228 SER A CB 1 ATOM 1764 O OG . SER A 1 227 ? -43.242 38.763 -29.912 1.00 36.48 ? 228 SER A OG 1 ATOM 1765 N N . PRO A 1 228 ? -46.722 39.962 -29.815 1.00 26.21 ? 229 PRO A N 1 ATOM 1766 C CA . PRO A 1 228 ? -47.802 40.935 -29.746 1.00 27.01 ? 229 PRO A CA 1 ATOM 1767 C C . PRO A 1 228 ? -47.539 42.132 -30.592 1.00 26.94 ? 229 PRO A C 1 ATOM 1768 O O . PRO A 1 228 ? -48.486 42.741 -31.128 1.00 25.03 ? 229 PRO A O 1 ATOM 1769 C CB . PRO A 1 228 ? -47.851 41.307 -28.248 1.00 27.32 ? 229 PRO A CB 1 ATOM 1770 C CG . PRO A 1 228 ? -46.502 40.915 -27.717 1.00 26.86 ? 229 PRO A CG 1 ATOM 1771 C CD . PRO A 1 228 ? -46.002 39.802 -28.542 1.00 25.91 ? 229 PRO A CD 1 ATOM 1772 N N . ASN A 1 229 ? -46.246 42.451 -30.734 1.00 27.50 ? 230 ASN A N 1 ATOM 1773 C CA . ASN A 1 229 ? -45.791 43.582 -31.565 1.00 30.39 ? 230 ASN A CA 1 ATOM 1774 C C . ASN A 1 229 ? -45.659 43.289 -33.080 1.00 30.06 ? 230 ASN A C 1 ATOM 1775 O O . ASN A 1 229 ? -45.255 44.134 -33.837 1.00 32.64 ? 230 ASN A O 1 ATOM 1776 C CB . ASN A 1 229 ? -44.437 44.080 -31.079 1.00 27.16 ? 230 ASN A CB 1 ATOM 1777 C CG . ASN A 1 229 ? -43.431 42.957 -30.976 1.00 29.79 ? 230 ASN A CG 1 ATOM 1778 O OD1 . ASN A 1 229 ? -43.756 41.856 -30.471 1.00 32.63 ? 230 ASN A OD1 1 ATOM 1779 N ND2 . ASN A 1 229 ? -42.230 43.184 -31.440 1.00 26.79 ? 230 ASN A ND2 1 ATOM 1780 N N . CYS A 1 230 ? -46.011 42.109 -33.543 1.00 32.45 ? 231 CYS A N 1 ATOM 1781 C CA . CYS A 1 230 ? -45.961 41.855 -34.997 1.00 28.37 ? 231 CYS A CA 1 ATOM 1782 C C . CYS A 1 230 ? -46.701 42.990 -35.794 1.00 31.30 ? 231 CYS A C 1 ATOM 1783 O O . CYS A 1 230 ? -47.789 43.499 -35.365 1.00 28.01 ? 231 CYS A O 1 ATOM 1784 C CB . CYS A 1 230 ? -46.586 40.499 -35.278 1.00 26.84 ? 231 CYS A CB 1 ATOM 1785 S SG . CYS A 1 230 ? -45.419 39.159 -34.830 1.00 26.26 ? 231 CYS A SG 1 ATOM 1786 N N . PRO A 1 231 ? -46.134 43.397 -36.948 1.00 27.36 ? 232 PRO A N 1 ATOM 1787 C CA . PRO A 1 231 ? -46.713 44.477 -37.783 1.00 24.20 ? 232 PRO A CA 1 ATOM 1788 C C . PRO A 1 231 ? -48.119 44.160 -38.280 1.00 25.16 ? 232 PRO A C 1 ATOM 1789 O O . PRO A 1 231 ? -48.900 45.023 -38.511 1.00 24.16 ? 232 PRO A O 1 ATOM 1790 C CB . PRO A 1 231 ? -45.697 44.606 -38.913 1.00 24.63 ? 232 PRO A CB 1 ATOM 1791 C CG . PRO A 1 231 ? -44.954 43.288 -38.956 1.00 26.93 ? 232 PRO A CG 1 ATOM 1792 C CD . PRO A 1 231 ? -44.922 42.810 -37.545 1.00 27.79 ? 232 PRO A CD 1 ATOM 1793 N N . TRP A 1 232 ? -48.475 42.876 -38.372 1.00 26.26 ? 233 TRP A N 1 ATOM 1794 C CA . TRP A 1 232 ? -49.795 42.462 -38.785 1.00 21.92 ? 233 TRP A CA 1 ATOM 1795 C C . TRP A 1 232 ? -50.818 42.237 -37.640 1.00 23.60 ? 233 TRP A C 1 ATOM 1796 O O . TRP A 1 232 ? -52.005 41.994 -37.917 1.00 22.87 ? 233 TRP A O 1 ATOM 1797 C CB . TRP A 1 232 ? -49.666 41.138 -39.540 1.00 21.58 ? 233 TRP A CB 1 ATOM 1798 C CG . TRP A 1 232 ? -48.858 40.078 -38.847 1.00 21.82 ? 233 TRP A CG 1 ATOM 1799 C CD1 . TRP A 1 232 ? -47.524 39.834 -38.994 1.00 24.11 ? 233 TRP A CD1 1 ATOM 1800 C CD2 . TRP A 1 232 ? -49.321 39.146 -37.869 1.00 23.35 ? 233 TRP A CD2 1 ATOM 1801 N NE1 . TRP A 1 232 ? -47.130 38.815 -38.154 1.00 23.43 ? 233 TRP A NE1 1 ATOM 1802 C CE2 . TRP A 1 232 ? -48.245 38.359 -37.492 1.00 23.99 ? 233 TRP A CE2 1 ATOM 1803 C CE3 . TRP A 1 232 ? -50.576 38.863 -37.325 1.00 27.35 ? 233 TRP A CE3 1 ATOM 1804 C CZ2 . TRP A 1 232 ? -48.379 37.307 -36.596 1.00 26.73 ? 233 TRP A CZ2 1 ATOM 1805 C CZ3 . TRP A 1 232 ? -50.689 37.814 -36.424 1.00 25.78 ? 233 TRP A CZ3 1 ATOM 1806 C CH2 . TRP A 1 232 ? -49.588 37.104 -36.035 1.00 25.87 ? 233 TRP A CH2 1 ATOM 1807 N N . ALA A 1 233 ? -50.377 42.204 -36.384 1.00 23.02 ? 234 ALA A N 1 ATOM 1808 C CA . ALA A 1 233 ? -51.268 41.748 -35.287 1.00 22.93 ? 234 ALA A CA 1 ATOM 1809 C C . ALA A 1 233 ? -52.140 42.828 -34.643 1.00 24.12 ? 234 ALA A C 1 ATOM 1810 O O . ALA A 1 233 ? -52.950 42.491 -33.832 1.00 25.31 ? 234 ALA A O 1 ATOM 1811 C CB . ALA A 1 233 ? -50.446 41.113 -34.212 1.00 22.78 ? 234 ALA A CB 1 ATOM 1812 N N . SER A 1 234 ? -51.975 44.103 -34.977 1.00 26.31 ? 235 SER A N 1 ATOM 1813 C CA . SER A 1 234 ? -52.799 45.194 -34.412 1.00 26.81 ? 235 SER A CA 1 ATOM 1814 C C . SER A 1 234 ? -52.858 46.367 -35.380 1.00 26.96 ? 235 SER A C 1 ATOM 1815 O O . SER A 1 234 ? -52.015 46.479 -36.237 1.00 25.68 ? 235 SER A O 1 ATOM 1816 C CB . SER A 1 234 ? -52.262 45.700 -33.081 1.00 26.76 ? 235 SER A CB 1 ATOM 1817 O OG . SER A 1 234 ? -50.954 46.246 -33.158 1.00 24.73 ? 235 SER A OG 1 ATOM 1818 N N . VAL A 1 235 ? -53.892 47.178 -35.251 1.00 25.51 ? 236 VAL A N 1 ATOM 1819 C CA . VAL A 1 235 ? -54.014 48.445 -35.963 1.00 27.20 ? 236 VAL A CA 1 ATOM 1820 C C . VAL A 1 235 ? -54.490 49.546 -34.971 1.00 29.24 ? 236 VAL A C 1 ATOM 1821 O O . VAL A 1 235 ? -55.087 49.269 -33.909 1.00 26.28 ? 236 VAL A O 1 ATOM 1822 C CB . VAL A 1 235 ? -55.130 48.335 -37.060 1.00 27.36 ? 236 VAL A CB 1 ATOM 1823 C CG1 . VAL A 1 235 ? -54.725 47.286 -38.099 1.00 28.04 ? 236 VAL A CG1 1 ATOM 1824 C CG2 . VAL A 1 235 ? -56.478 47.942 -36.443 1.00 25.68 ? 236 VAL A CG2 1 ATOM 1825 N N . SER A 1 236 ? -54.271 50.778 -35.354 1.00 27.44 ? 237 SER A N 1 ATOM 1826 C CA . SER A 1 236 ? -54.700 51.917 -34.575 1.00 29.23 ? 237 SER A CA 1 ATOM 1827 C C . SER A 1 236 ? -56.227 51.960 -34.568 1.00 28.39 ? 237 SER A C 1 ATOM 1828 O O . SER A 1 236 ? -56.855 51.315 -35.425 1.00 23.78 ? 237 SER A O 1 ATOM 1829 C CB . SER A 1 236 ? -54.154 53.213 -35.244 1.00 28.27 ? 237 SER A CB 1 ATOM 1830 O OG . SER A 1 236 ? -54.848 53.392 -36.490 1.00 31.53 ? 237 SER A OG 1 ATOM 1831 N N . VAL A 1 237 ? -56.826 52.762 -33.665 1.00 27.09 ? 238 VAL A N 1 ATOM 1832 C CA . VAL A 1 237 ? -58.292 52.881 -33.682 1.00 30.45 ? 238 VAL A CA 1 ATOM 1833 C C . VAL A 1 237 ? -58.772 53.540 -34.937 1.00 28.60 ? 238 VAL A C 1 ATOM 1834 O O . VAL A 1 237 ? -59.844 53.170 -35.451 1.00 26.14 ? 238 VAL A O 1 ATOM 1835 C CB . VAL A 1 237 ? -58.906 53.617 -32.460 1.00 35.57 ? 238 VAL A CB 1 ATOM 1836 C CG1 . VAL A 1 237 ? -58.623 52.863 -31.163 1.00 40.31 ? 238 VAL A CG1 1 ATOM 1837 C CG2 . VAL A 1 237 ? -58.335 54.987 -32.309 1.00 38.08 ? 238 VAL A CG2 1 ATOM 1838 N N . ALA A 1 238 ? -58.027 54.537 -35.412 1.00 27.86 ? 239 ALA A N 1 ATOM 1839 C CA . ALA A 1 238 ? -58.429 55.244 -36.652 1.00 30.82 ? 239 ALA A CA 1 ATOM 1840 C C . ALA A 1 238 ? -58.467 54.235 -37.831 1.00 30.65 ? 239 ALA A C 1 ATOM 1841 O O . ALA A 1 238 ? -59.445 54.161 -38.569 1.00 29.92 ? 239 ALA A O 1 ATOM 1842 C CB . ALA A 1 238 ? -57.441 56.385 -36.951 1.00 29.99 ? 239 ALA A CB 1 ATOM 1843 N N . GLU A 1 239 ? -57.436 53.378 -37.927 1.00 31.83 ? 240 GLU A N 1 ATOM 1844 C CA . GLU A 1 239 ? -57.402 52.383 -39.015 1.00 30.81 ? 240 GLU A CA 1 ATOM 1845 C C . GLU A 1 239 ? -58.511 51.345 -38.904 1.00 29.22 ? 240 GLU A C 1 ATOM 1846 O O . GLU A 1 239 ? -59.172 50.973 -39.918 1.00 27.46 ? 240 GLU A O 1 ATOM 1847 C CB . GLU A 1 239 ? -56.022 51.769 -39.129 1.00 30.06 ? 240 GLU A CB 1 ATOM 1848 C CG . GLU A 1 239 ? -55.922 50.688 -40.192 1.00 32.50 ? 240 GLU A CG 1 ATOM 1849 C CD . GLU A 1 239 ? -56.128 51.200 -41.620 1.00 33.62 ? 240 GLU A CD 1 ATOM 1850 O OE1 . GLU A 1 239 ? -56.187 52.438 -41.857 1.00 31.39 ? 240 GLU A OE1 1 ATOM 1851 O OE2 . GLU A 1 239 ? -56.286 50.322 -42.486 1.00 29.09 ? 240 GLU A OE2 1 ATOM 1852 N N . GLY A 1 240 ? -58.771 50.909 -37.667 1.00 31.31 ? 241 GLY A N 1 ATOM 1853 C CA . GLY A 1 240 ? -59.926 50.012 -37.355 1.00 29.30 ? 241 GLY A CA 1 ATOM 1854 C C . GLY A 1 240 ? -61.241 50.580 -37.832 1.00 27.64 ? 241 GLY A C 1 ATOM 1855 O O . GLY A 1 240 ? -62.065 49.925 -38.482 1.00 27.10 ? 241 GLY A O 1 ATOM 1856 N N . ARG A 1 241 ? -61.408 51.837 -37.530 1.00 29.40 ? 242 ARG A N 1 ATOM 1857 C CA . ARG A 1 241 ? -62.607 52.540 -37.892 1.00 34.18 ? 242 ARG A CA 1 ATOM 1858 C C . ARG A 1 241 ? -62.743 52.564 -39.411 1.00 30.57 ? 242 ARG A C 1 ATOM 1859 O O . ARG A 1 241 ? -63.778 52.177 -39.985 1.00 33.67 ? 242 ARG A O 1 ATOM 1860 C CB . ARG A 1 241 ? -62.531 53.976 -37.308 1.00 37.78 ? 242 ARG A CB 1 ATOM 1861 C CG . ARG A 1 241 ? -63.769 54.825 -37.580 1.00 42.20 ? 242 ARG A CG 1 ATOM 1862 C CD . ARG A 1 241 ? -63.960 56.068 -36.647 1.00 41.33 ? 242 ARG A CD 1 ATOM 1863 N NE . ARG A 1 241 ? -64.456 55.687 -35.322 1.00 36.99 ? 242 ARG A NE 1 ATOM 1864 C CZ . ARG A 1 241 ? -65.718 55.413 -35.048 1.00 40.10 ? 242 ARG A CZ 1 ATOM 1865 N NH1 . ARG A 1 241 ? -66.663 55.502 -35.992 1.00 37.65 ? 242 ARG A NH1 1 ATOM 1866 N NH2 . ARG A 1 241 ? -66.058 55.023 -33.824 1.00 43.22 ? 242 ARG A NH2 1 ATOM 1867 N N . ARG A 1 242 ? -61.683 52.995 -40.054 1.00 28.32 ? 243 ARG A N 1 ATOM 1868 C CA . ARG A 1 242 ? -61.672 53.099 -41.514 1.00 34.06 ? 243 ARG A CA 1 ATOM 1869 C C . ARG A 1 242 ? -62.096 51.792 -42.148 1.00 31.70 ? 243 ARG A C 1 ATOM 1870 O O . ARG A 1 242 ? -62.997 51.779 -43.009 1.00 32.32 ? 243 ARG A O 1 ATOM 1871 C CB . ARG A 1 242 ? -60.281 53.499 -41.969 1.00 38.00 ? 243 ARG A CB 1 ATOM 1872 C CG . ARG A 1 242 ? -60.091 54.210 -43.298 1.00 37.93 ? 243 ARG A CG 1 ATOM 1873 C CD . ARG A 1 242 ? -58.751 53.756 -43.975 1.00 41.35 ? 243 ARG A CD 1 ATOM 1874 N NE . ARG A 1 242 ? -59.177 52.773 -44.967 1.00 48.09 ? 243 ARG A NE 1 ATOM 1875 C CZ . ARG A 1 242 ? -58.766 51.546 -45.184 1.00 43.96 ? 243 ARG A CZ 1 ATOM 1876 N NH1 . ARG A 1 242 ? -57.740 51.001 -44.584 1.00 45.12 ? 243 ARG A NH1 1 ATOM 1877 N NH2 . ARG A 1 242 ? -59.381 50.896 -46.144 1.00 57.94 ? 243 ARG A NH2 1 ATOM 1878 N N . ARG A 1 243 ? -61.558 50.675 -41.642 1.00 29.81 ? 244 ARG A N 1 ATOM 1879 C CA . ARG A 1 243 ? -61.848 49.406 -42.269 1.00 27.69 ? 244 ARG A CA 1 ATOM 1880 C C . ARG A 1 243 ? -63.243 49.003 -42.013 1.00 29.13 ? 244 ARG A C 1 ATOM 1881 O O . ARG A 1 243 ? -63.828 48.278 -42.874 1.00 30.86 ? 244 ARG A O 1 ATOM 1882 C CB . ARG A 1 243 ? -60.892 48.238 -41.844 1.00 26.41 ? 244 ARG A CB 1 ATOM 1883 C CG . ARG A 1 243 ? -59.438 48.573 -42.086 1.00 24.29 ? 244 ARG A CG 1 ATOM 1884 C CD . ARG A 1 243 ? -58.516 47.472 -41.619 1.00 25.54 ? 244 ARG A CD 1 ATOM 1885 N NE . ARG A 1 243 ? -57.085 47.819 -41.824 1.00 24.43 ? 244 ARG A NE 1 ATOM 1886 C CZ . ARG A 1 243 ? -56.081 46.971 -41.641 1.00 23.98 ? 244 ARG A CZ 1 ATOM 1887 N NH1 . ARG A 1 243 ? -56.290 45.690 -41.277 1.00 26.71 ? 244 ARG A NH1 1 ATOM 1888 N NH2 . ARG A 1 243 ? -54.855 47.388 -41.804 1.00 25.18 ? 244 ARG A NH2 1 ATOM 1889 N N . ALA A 1 244 ? -63.787 49.374 -40.843 1.00 28.48 ? 245 ALA A N 1 ATOM 1890 C CA . ALA A 1 244 ? -65.198 49.011 -40.540 1.00 31.51 ? 245 ALA A CA 1 ATOM 1891 C C . ALA A 1 244 ? -66.163 49.773 -41.421 1.00 32.24 ? 245 ALA A C 1 ATOM 1892 O O . ALA A 1 244 ? -67.113 49.197 -41.885 1.00 32.04 ? 245 ALA A O 1 ATOM 1893 C CB . ALA A 1 244 ? -65.539 49.272 -39.086 1.00 38.01 ? 245 ALA A CB 1 ATOM 1894 N N . VAL A 1 245 ? -65.904 51.069 -41.637 1.00 33.70 ? 246 VAL A N 1 ATOM 1895 C CA . VAL A 1 245 ? -66.661 51.853 -42.601 1.00 35.69 ? 246 VAL A CA 1 ATOM 1896 C C . VAL A 1 245 ? -66.542 51.316 -44.056 1.00 35.32 ? 246 VAL A C 1 ATOM 1897 O O . VAL A 1 245 ? -67.538 51.182 -44.758 1.00 38.48 ? 246 VAL A O 1 ATOM 1898 C CB . VAL A 1 245 ? -66.220 53.318 -42.552 1.00 39.33 ? 246 VAL A CB 1 ATOM 1899 C CG1 . VAL A 1 245 ? -66.943 54.149 -43.623 1.00 37.31 ? 246 VAL A CG1 1 ATOM 1900 C CG2 . VAL A 1 245 ? -66.495 53.888 -41.152 1.00 37.25 ? 246 VAL A CG2 1 ATOM 1901 N N . GLU A 1 246 ? -65.336 50.966 -44.481 1.00 34.04 ? 247 GLU A N 1 ATOM 1902 C CA . GLU A 1 246 ? -65.145 50.384 -45.787 1.00 34.71 ? 247 GLU A CA 1 ATOM 1903 C C . GLU A 1 246 ? -65.911 49.083 -45.931 1.00 36.28 ? 247 GLU A C 1 ATOM 1904 O O . GLU A 1 246 ? -66.549 48.778 -47.015 1.00 33.82 ? 247 GLU A O 1 ATOM 1905 C CB . GLU A 1 246 ? -63.669 50.223 -46.064 1.00 35.74 ? 247 GLU A CB 1 ATOM 1906 C CG . GLU A 1 246 ? -63.324 49.835 -47.472 1.00 43.96 ? 247 GLU A CG 1 ATOM 1907 C CD . GLU A 1 246 ? -63.751 50.878 -48.544 1.00 46.82 ? 247 GLU A CD 1 ATOM 1908 O OE1 . GLU A 1 246 ? -63.959 52.074 -48.252 1.00 42.87 ? 247 GLU A OE1 1 ATOM 1909 O OE2 . GLU A 1 246 ? -63.913 50.447 -49.692 1.00 43.76 ? 247 GLU A OE2 1 ATOM 1910 N N . LEU A 1 247 ? -65.943 48.316 -44.844 1.00 32.87 ? 248 LEU A N 1 ATOM 1911 C CA . LEU A 1 247 ? -66.670 47.064 -44.886 1.00 28.49 ? 248 LEU A CA 1 ATOM 1912 C C . LEU A 1 247 ? -68.093 47.381 -45.108 1.00 31.73 ? 248 LEU A C 1 ATOM 1913 O O . LEU A 1 247 ? -68.757 46.722 -45.884 1.00 34.35 ? 248 LEU A O 1 ATOM 1914 C CB . LEU A 1 247 ? -66.537 46.287 -43.574 1.00 30.15 ? 248 LEU A CB 1 ATOM 1915 C CG . LEU A 1 247 ? -67.224 44.907 -43.578 1.00 31.48 ? 248 LEU A CG 1 ATOM 1916 C CD1 . LEU A 1 247 ? -66.456 43.923 -44.463 1.00 34.51 ? 248 LEU A CD1 1 ATOM 1917 C CD2 . LEU A 1 247 ? -67.422 44.300 -42.183 1.00 32.44 ? 248 LEU A CD2 1 ATOM 1918 N N . GLY A 1 248 ? -68.618 48.362 -44.390 1.00 32.75 ? 249 GLY A N 1 ATOM 1919 C CA . GLY A 1 248 ? -70.049 48.726 -44.597 1.00 36.73 ? 249 GLY A CA 1 ATOM 1920 C C . GLY A 1 248 ? -70.342 49.270 -46.004 1.00 33.40 ? 249 GLY A C 1 ATOM 1921 O O . GLY A 1 248 ? -71.382 49.003 -46.598 1.00 30.84 ? 249 GLY A O 1 ATOM 1922 N N . ARG A 1 249 ? -69.392 50.005 -46.535 1.00 32.88 ? 250 ARG A N 1 ATOM 1923 C CA . ARG A 1 249 ? -69.481 50.451 -47.875 1.00 35.85 ? 250 ARG A CA 1 ATOM 1924 C C . ARG A 1 249 ? -69.565 49.298 -48.892 1.00 38.71 ? 250 ARG A C 1 ATOM 1925 O O . ARG A 1 249 ? -70.280 49.386 -49.850 1.00 37.88 ? 250 ARG A O 1 ATOM 1926 C CB . ARG A 1 249 ? -68.315 51.349 -48.142 1.00 41.10 ? 250 ARG A CB 1 ATOM 1927 C CG . ARG A 1 249 ? -68.472 52.164 -49.426 1.00 48.22 ? 250 ARG A CG 1 ATOM 1928 C CD . ARG A 1 249 ? -67.213 52.984 -49.709 1.00 46.14 ? 250 ARG A CD 1 ATOM 1929 N NE . ARG A 1 249 ? -66.777 53.732 -48.519 1.00 55.91 ? 250 ARG A NE 1 ATOM 1930 C CZ . ARG A 1 249 ? -67.115 54.998 -48.229 1.00 62.58 ? 250 ARG A CZ 1 ATOM 1931 N NH1 . ARG A 1 249 ? -67.924 55.686 -49.041 1.00 71.22 ? 250 ARG A NH1 1 ATOM 1932 N NH2 . ARG A 1 249 ? -66.636 55.600 -47.123 1.00 57.63 ? 250 ARG A NH2 1 ATOM 1933 N N . ASN A 1 250 ? -68.871 48.191 -48.659 1.00 40.56 ? 251 ASN A N 1 ATOM 1934 C CA . ASN A 1 250 ? -68.936 47.055 -49.553 1.00 34.87 ? 251 ASN A CA 1 ATOM 1935 C C . ASN A 1 250 ? -70.233 46.329 -49.463 1.00 34.33 ? 251 ASN A C 1 ATOM 1936 O O . ASN A 1 250 ? -70.532 45.486 -50.339 1.00 38.62 ? 251 ASN A O 1 ATOM 1937 C CB . ASN A 1 250 ? -67.844 46.020 -49.228 1.00 37.73 ? 251 ASN A CB 1 ATOM 1938 C CG . ASN A 1 250 ? -66.479 46.377 -49.806 1.00 33.77 ? 251 ASN A CG 1 ATOM 1939 O OD1 . ASN A 1 250 ? -66.056 45.764 -50.751 1.00 35.00 ? 251 ASN A OD1 1 ATOM 1940 N ND2 . ASN A 1 250 ? -65.790 47.305 -49.213 1.00 35.03 ? 251 ASN A ND2 1 ATOM 1941 N N . LEU A 1 251 ? -70.999 46.578 -48.399 1.00 37.45 ? 252 LEU A N 1 ATOM 1942 C CA . LEU A 1 251 ? -72.320 45.934 -48.229 1.00 37.01 ? 252 LEU A CA 1 ATOM 1943 C C . LEU A 1 251 ? -73.502 46.918 -48.369 1.00 40.44 ? 252 LEU A C 1 ATOM 1944 O O . LEU A 1 251 ? -74.610 46.606 -47.966 1.00 41.23 ? 252 LEU A O 1 ATOM 1945 C CB . LEU A 1 251 ? -72.374 45.193 -46.904 1.00 36.67 ? 252 LEU A CB 1 ATOM 1946 C CG . LEU A 1 251 ? -71.345 44.079 -46.871 1.00 36.85 ? 252 LEU A CG 1 ATOM 1947 C CD1 . LEU A 1 251 ? -70.903 43.653 -45.488 1.00 36.70 ? 252 LEU A CD1 1 ATOM 1948 C CD2 . LEU A 1 251 ? -71.833 42.867 -47.629 1.00 37.20 ? 252 LEU A CD2 1 ATOM 1949 N N . ASN A 1 252 ? -73.262 48.081 -48.980 1.00 46.37 ? 253 ASN A N 1 ATOM 1950 C CA . ASN A 1 252 ? -74.328 49.082 -49.247 1.00 55.36 ? 253 ASN A CA 1 ATOM 1951 C C . ASN A 1 252 ? -75.038 49.497 -47.940 1.00 52.78 ? 253 ASN A C 1 ATOM 1952 O O . ASN A 1 252 ? -76.252 49.559 -47.913 1.00 47.01 ? 253 ASN A O 1 ATOM 1953 C CB . ASN A 1 252 ? -75.394 48.572 -50.258 1.00 56.72 ? 253 ASN A CB 1 ATOM 1954 C CG . ASN A 1 252 ? -74.811 47.679 -51.377 1.00 67.65 ? 253 ASN A CG 1 ATOM 1955 O OD1 . ASN A 1 252 ? -75.145 46.472 -51.472 1.00 62.43 ? 253 ASN A OD1 1 ATOM 1956 N ND2 . ASN A 1 252 ? -73.937 48.253 -52.216 1.00 64.52 ? 253 ASN A ND2 1 ATOM 1957 N N . CYS A 1 253 ? -74.263 49.708 -46.875 1.00 45.75 ? 254 CYS A N 1 ATOM 1958 C CA . CYS A 1 253 ? -74.779 50.162 -45.594 1.00 42.00 ? 254 CYS A CA 1 ATOM 1959 C C . CYS A 1 253 ? -74.950 51.650 -45.526 1.00 41.39 ? 254 CYS A C 1 ATOM 1960 O O . CYS A 1 253 ? -74.188 52.441 -46.113 1.00 37.63 ? 254 CYS A O 1 ATOM 1961 C CB . CYS A 1 253 ? -73.850 49.801 -44.423 1.00 41.37 ? 254 CYS A CB 1 ATOM 1962 S SG . CYS A 1 253 ? -73.773 48.040 -44.031 1.00 42.52 ? 254 CYS A SG 1 ATOM 1963 N N . ASN A 1 254 ? -75.935 52.036 -44.715 1.00 47.34 ? 255 ASN A N 1 ATOM 1964 C CA . ASN A 1 254 ? -75.980 53.388 -44.194 1.00 45.73 ? 255 ASN A CA 1 ATOM 1965 C C . ASN A 1 254 ? -74.745 53.699 -43.376 1.00 39.27 ? 255 ASN A C 1 ATOM 1966 O O . ASN A 1 254 ? -74.465 52.996 -42.409 1.00 43.97 ? 255 ASN A O 1 ATOM 1967 C CB . ASN A 1 254 ? -77.216 53.553 -43.324 1.00 51.12 ? 255 ASN A CB 1 ATOM 1968 C CG . ASN A 1 254 ? -77.545 55.019 -43.066 1.00 51.69 ? 255 ASN A CG 1 ATOM 1969 O OD1 . ASN A 1 254 ? -76.723 55.817 -42.600 1.00 46.09 ? 255 ASN A OD1 1 ATOM 1970 N ND2 . ASN A 1 254 ? -78.747 55.381 -43.429 1.00 59.26 ? 255 ASN A ND2 1 ATOM 1971 N N . LEU A 1 255 ? -74.039 54.767 -43.730 1.00 41.50 ? 256 LEU A N 1 ATOM 1972 C CA . LEU A 1 255 ? -72.784 55.164 -43.065 1.00 41.30 ? 256 LEU A CA 1 ATOM 1973 C C . LEU A 1 255 ? -72.858 56.454 -42.251 1.00 47.62 ? 256 LEU A C 1 ATOM 1974 O O . LEU A 1 255 ? -71.803 56.986 -41.843 1.00 41.59 ? 256 LEU A O 1 ATOM 1975 C CB . LEU A 1 255 ? -71.668 55.351 -44.101 1.00 39.15 ? 256 LEU A CB 1 ATOM 1976 C CG . LEU A 1 255 ? -71.490 54.164 -45.060 1.00 43.58 ? 256 LEU A CG 1 ATOM 1977 C CD1 . LEU A 1 255 ? -70.301 54.485 -45.951 1.00 45.27 ? 256 LEU A CD1 1 ATOM 1978 C CD2 . LEU A 1 255 ? -71.268 52.842 -44.329 1.00 41.44 ? 256 LEU A CD2 1 ATOM 1979 N N . ASN A 1 256 ? -74.071 56.937 -41.960 1.00 50.82 ? 257 ASN A N 1 ATOM 1980 C CA . ASN A 1 256 ? -74.207 58.211 -41.207 1.00 55.24 ? 257 ASN A CA 1 ATOM 1981 C C . ASN A 1 256 ? -73.757 58.168 -39.774 1.00 51.68 ? 257 ASN A C 1 ATOM 1982 O O . ASN A 1 256 ? -73.421 59.199 -39.215 1.00 54.87 ? 257 ASN A O 1 ATOM 1983 C CB . ASN A 1 256 ? -75.661 58.690 -41.171 1.00 64.54 ? 257 ASN A CB 1 ATOM 1984 C CG . ASN A 1 256 ? -76.102 59.323 -42.474 1.00 70.52 ? 257 ASN A CG 1 ATOM 1985 O OD1 . ASN A 1 256 ? -75.272 59.776 -43.280 1.00 77.19 ? 257 ASN A OD1 1 ATOM 1986 N ND2 . ASN A 1 256 ? -77.418 59.349 -42.697 1.00 76.80 ? 257 ASN A ND2 1 ATOM 1987 N N . SER A 1 257 ? -73.819 56.994 -39.158 1.00 45.67 ? 258 SER A N 1 ATOM 1988 C CA . SER A 1 257 ? -73.495 56.869 -37.755 1.00 42.07 ? 258 SER A CA 1 ATOM 1989 C C . SER A 1 257 ? -73.007 55.456 -37.509 1.00 39.86 ? 258 SER A C 1 ATOM 1990 O O . SER A 1 257 ? -73.304 54.528 -38.257 1.00 43.11 ? 258 SER A O 1 ATOM 1991 C CB . SER A 1 257 ? -74.750 57.163 -36.877 1.00 35.32 ? 258 SER A CB 1 ATOM 1992 O OG . SER A 1 257 ? -75.831 56.252 -37.196 1.00 36.84 ? 258 SER A OG 1 ATOM 1993 N N . ASP A 1 258 ? -72.312 55.303 -36.404 1.00 40.68 ? 259 ASP A N 1 ATOM 1994 C CA . ASP A 1 258 ? -71.913 54.007 -35.904 1.00 39.66 ? 259 ASP A CA 1 ATOM 1995 C C . ASP A 1 258 ? -73.089 53.108 -35.734 1.00 41.88 ? 259 ASP A C 1 ATOM 1996 O O . ASP A 1 258 ? -73.003 51.930 -36.056 1.00 41.61 ? 259 ASP A O 1 ATOM 1997 C CB . ASP A 1 258 ? -71.192 54.156 -34.551 1.00 38.32 ? 259 ASP A CB 1 ATOM 1998 C CG . ASP A 1 258 ? -69.769 54.698 -34.683 1.00 41.50 ? 259 ASP A CG 1 ATOM 1999 O OD1 . ASP A 1 258 ? -69.329 54.997 -35.809 1.00 46.70 ? 259 ASP A OD1 1 ATOM 2000 O OD2 . ASP A 1 258 ? -69.047 54.831 -33.658 1.00 48.49 ? 259 ASP A OD2 1 ATOM 2001 N N . GLU A 1 259 ? -74.190 53.665 -35.220 1.00 47.85 ? 260 GLU A N 1 ATOM 2002 C CA . GLU A 1 259 ? -75.400 52.885 -34.907 1.00 48.46 ? 260 GLU A CA 1 ATOM 2003 C C . GLU A 1 259 ? -75.958 52.374 -36.183 1.00 44.68 ? 260 GLU A C 1 ATOM 2004 O O . GLU A 1 259 ? -76.373 51.205 -36.259 1.00 48.70 ? 260 GLU A O 1 ATOM 2005 C CB . GLU A 1 259 ? -76.496 53.728 -34.222 1.00 60.08 ? 260 GLU A CB 1 ATOM 2006 C CG . GLU A 1 259 ? -76.144 54.361 -32.868 1.00 72.38 ? 260 GLU A CG 1 ATOM 2007 C CD . GLU A 1 259 ? -74.848 55.209 -32.863 1.00 85.27 ? 260 GLU A CD 1 ATOM 2008 O OE1 . GLU A 1 259 ? -74.567 55.972 -33.830 1.00 74.41 ? 260 GLU A OE1 1 ATOM 2009 O OE2 . GLU A 1 259 ? -74.080 55.106 -31.869 1.00 96.62 ? 260 GLU A OE2 1 ATOM 2010 N N . GLU A 1 260 ? -76.019 53.270 -37.175 1.00 46.58 ? 261 GLU A N 1 ATOM 2011 C CA . GLU A 1 260 ? -76.487 52.918 -38.530 1.00 49.85 ? 261 GLU A CA 1 ATOM 2012 C C . GLU A 1 260 ? -75.608 51.775 -39.165 1.00 44.73 ? 261 GLU A C 1 ATOM 2013 O O . GLU A 1 260 ? -76.134 50.752 -39.643 1.00 36.07 ? 261 GLU A O 1 ATOM 2014 C CB . GLU A 1 260 ? -76.479 54.169 -39.443 1.00 59.37 ? 261 GLU A CB 1 ATOM 2015 C CG . GLU A 1 260 ? -77.433 55.332 -39.072 1.00 68.35 ? 261 GLU A CG 1 ATOM 2016 C CD . GLU A 1 260 ? -78.825 55.193 -39.699 1.00 74.05 ? 261 GLU A CD 1 ATOM 2017 O OE1 . GLU A 1 260 ? -79.209 54.078 -40.144 1.00 68.74 ? 261 GLU A OE1 1 ATOM 2018 O OE2 . GLU A 1 260 ? -79.544 56.212 -39.747 1.00 73.63 ? 261 GLU A OE2 1 ATOM 2019 N N . LEU A 1 261 ? -74.283 51.926 -39.111 1.00 37.53 ? 262 LEU A N 1 ATOM 2020 C CA . LEU A 1 261 ? -73.374 50.934 -39.695 1.00 37.93 ? 262 LEU A CA 1 ATOM 2021 C C . LEU A 1 261 ? -73.540 49.576 -39.016 1.00 39.18 ? 262 LEU A C 1 ATOM 2022 O O . LEU A 1 261 ? -73.811 48.503 -39.669 1.00 34.78 ? 262 LEU A O 1 ATOM 2023 C CB . LEU A 1 261 ? -71.958 51.462 -39.593 1.00 38.42 ? 262 LEU A CB 1 ATOM 2024 C CG . LEU A 1 261 ? -70.800 50.569 -39.986 1.00 37.43 ? 262 LEU A CG 1 ATOM 2025 C CD1 . LEU A 1 261 ? -70.935 50.060 -41.380 1.00 36.92 ? 262 LEU A CD1 1 ATOM 2026 C CD2 . LEU A 1 261 ? -69.530 51.394 -39.857 1.00 39.25 ? 262 LEU A CD2 1 ATOM 2027 N N . ILE A 1 262 ? -73.505 49.643 -37.694 1.00 34.26 ? 263 ILE A N 1 ATOM 2028 C CA . ILE A 1 262 ? -73.536 48.431 -36.920 1.00 37.70 ? 263 ILE A CA 1 ATOM 2029 C C . ILE A 1 262 ? -74.856 47.735 -37.149 1.00 33.66 ? 263 ILE A C 1 ATOM 2030 O O . ILE A 1 262 ? -74.887 46.547 -37.383 1.00 39.66 ? 263 ILE A O 1 ATOM 2031 C CB . ILE A 1 262 ? -73.262 48.659 -35.406 1.00 35.85 ? 263 ILE A CB 1 ATOM 2032 C CG1 . ILE A 1 262 ? -71.844 49.139 -35.188 1.00 39.93 ? 263 ILE A CG1 1 ATOM 2033 C CG2 . ILE A 1 262 ? -73.482 47.361 -34.707 1.00 39.71 ? 263 ILE A CG2 1 ATOM 2034 C CD1 . ILE A 1 262 ? -71.540 49.771 -33.848 1.00 40.81 ? 263 ILE A CD1 1 ATOM 2035 N N . HIS A 1 263 ? -75.952 48.453 -37.103 1.00 39.47 ? 264 HIS A N 1 ATOM 2036 C CA . HIS A 1 263 ? -77.244 47.802 -37.348 1.00 44.85 ? 264 HIS A CA 1 ATOM 2037 C C . HIS A 1 263 ? -77.225 47.124 -38.719 1.00 40.64 ? 264 HIS A C 1 ATOM 2038 O O . HIS A 1 263 ? -77.698 45.988 -38.861 1.00 43.17 ? 264 HIS A O 1 ATOM 2039 C CB . HIS A 1 263 ? -78.421 48.802 -37.250 1.00 51.16 ? 264 HIS A CB 1 ATOM 2040 C CG . HIS A 1 263 ? -79.754 48.196 -37.602 1.00 62.97 ? 264 HIS A CG 1 ATOM 2041 N ND1 . HIS A 1 263 ? -80.263 48.193 -38.893 1.00 67.49 ? 264 HIS A ND1 1 ATOM 2042 C CD2 . HIS A 1 263 ? -80.664 47.540 -36.840 1.00 66.03 ? 264 HIS A CD2 1 ATOM 2043 C CE1 . HIS A 1 263 ? -81.425 47.563 -38.909 1.00 65.89 ? 264 HIS A CE1 1 ATOM 2044 N NE2 . HIS A 1 263 ? -81.691 47.159 -37.677 1.00 69.71 ? 264 HIS A NE2 1 ATOM 2045 N N . CYS A 1 264 ? -76.689 47.822 -39.735 1.00 42.86 ? 265 CYS A N 1 ATOM 2046 C CA . CYS A 1 264 ? -76.659 47.264 -41.101 1.00 39.91 ? 265 CYS A CA 1 ATOM 2047 C C . CYS A 1 264 ? -75.800 45.996 -41.091 1.00 35.42 ? 265 CYS A C 1 ATOM 2048 O O . CYS A 1 264 ? -76.241 44.954 -41.591 1.00 30.38 ? 265 CYS A O 1 ATOM 2049 C CB . CYS A 1 264 ? -76.169 48.275 -42.170 1.00 42.90 ? 265 CYS A CB 1 ATOM 2050 S SG . CYS A 1 264 ? -75.671 47.425 -43.716 1.00 58.72 ? 265 CYS A SG 1 ATOM 2051 N N . LEU A 1 265 ? -74.608 46.051 -40.447 1.00 34.27 ? 266 LEU A N 1 ATOM 2052 C CA . LEU A 1 265 ? -73.737 44.838 -40.408 1.00 33.31 ? 266 LEU A CA 1 ATOM 2053 C C . LEU A 1 265 ? -74.382 43.701 -39.688 1.00 36.37 ? 266 LEU A C 1 ATOM 2054 O O . LEU A 1 265 ? -74.116 42.522 -39.983 1.00 37.74 ? 266 LEU A O 1 ATOM 2055 C CB . LEU A 1 265 ? -72.332 45.135 -39.868 1.00 31.81 ? 266 LEU A CB 1 ATOM 2056 C CG . LEU A 1 265 ? -71.570 46.182 -40.697 1.00 27.93 ? 266 LEU A CG 1 ATOM 2057 C CD1 . LEU A 1 265 ? -70.368 46.647 -39.939 1.00 30.67 ? 266 LEU A CD1 1 ATOM 2058 C CD2 . LEU A 1 265 ? -71.209 45.637 -42.069 1.00 30.96 ? 266 LEU A CD2 1 ATOM 2059 N N . ARG A 1 266 ? -75.254 44.018 -38.747 1.00 41.47 ? 267 ARG A N 1 ATOM 2060 C CA . ARG A 1 266 ? -75.820 42.956 -37.905 1.00 42.62 ? 267 ARG A CA 1 ATOM 2061 C C . ARG A 1 266 ? -76.909 42.249 -38.633 1.00 43.92 ? 267 ARG A C 1 ATOM 2062 O O . ARG A 1 266 ? -77.173 41.119 -38.291 1.00 43.78 ? 267 ARG A O 1 ATOM 2063 C CB . ARG A 1 266 ? -76.355 43.509 -36.605 1.00 45.39 ? 267 ARG A CB 1 ATOM 2064 C CG . ARG A 1 266 ? -75.272 43.872 -35.620 1.00 48.22 ? 267 ARG A CG 1 ATOM 2065 C CD . ARG A 1 266 ? -75.832 44.105 -34.251 1.00 45.88 ? 267 ARG A CD 1 ATOM 2066 N NE . ARG A 1 266 ? -74.746 44.221 -33.308 1.00 52.08 ? 267 ARG A NE 1 ATOM 2067 C CZ . ARG A 1 266 ? -74.784 44.970 -32.218 1.00 49.97 ? 267 ARG A CZ 1 ATOM 2068 N NH1 . ARG A 1 266 ? -75.865 45.669 -31.955 1.00 54.07 ? 267 ARG A NH1 1 ATOM 2069 N NH2 . ARG A 1 266 ? -73.739 45.025 -31.400 1.00 49.50 ? 267 ARG A NH2 1 ATOM 2070 N N . GLU A 1 267 ? -77.539 42.909 -39.615 1.00 44.66 ? 268 GLU A N 1 ATOM 2071 C CA . GLU A 1 267 ? -78.555 42.252 -40.491 1.00 47.62 ? 268 GLU A CA 1 ATOM 2072 C C . GLU A 1 267 ? -77.961 41.245 -41.498 1.00 44.90 ? 268 GLU A C 1 ATOM 2073 O O . GLU A 1 267 ? -78.671 40.405 -42.032 1.00 41.88 ? 268 GLU A O 1 ATOM 2074 C CB . GLU A 1 267 ? -79.388 43.319 -41.283 1.00 54.69 ? 268 GLU A CB 1 ATOM 2075 C CG . GLU A 1 267 ? -80.575 43.980 -40.523 1.00 65.32 ? 268 GLU A CG 1 ATOM 2076 C CD . GLU A 1 267 ? -81.275 43.022 -39.517 1.00 75.12 ? 268 GLU A CD 1 ATOM 2077 O OE1 . GLU A 1 267 ? -81.956 42.048 -39.942 1.00 79.87 ? 268 GLU A OE1 1 ATOM 2078 O OE2 . GLU A 1 267 ? -81.125 43.214 -38.281 1.00 74.40 ? 268 GLU A OE2 1 ATOM 2079 N N . LYS A 1 268 ? -76.664 41.354 -41.788 1.00 42.01 ? 269 LYS A N 1 ATOM 2080 C CA . LYS A 1 268 ? -76.073 40.597 -42.879 1.00 39.09 ? 269 LYS A CA 1 ATOM 2081 C C . LYS A 1 268 ? -75.803 39.175 -42.446 1.00 38.86 ? 269 LYS A C 1 ATOM 2082 O O . LYS A 1 268 ? -75.516 38.901 -41.291 1.00 40.37 ? 269 LYS A O 1 ATOM 2083 C CB . LYS A 1 268 ? -74.763 41.234 -43.284 1.00 40.74 ? 269 LYS A CB 1 ATOM 2084 C CG . LYS A 1 268 ? -74.887 42.648 -43.777 1.00 43.89 ? 269 LYS A CG 1 ATOM 2085 C CD . LYS A 1 268 ? -75.776 42.741 -45.025 1.00 44.89 ? 269 LYS A CD 1 ATOM 2086 C CE . LYS A 1 268 ? -76.112 44.198 -45.269 1.00 48.92 ? 269 LYS A CE 1 ATOM 2087 N NZ . LYS A 1 268 ? -76.712 44.438 -46.608 1.00 59.08 ? 269 LYS A NZ 1 ATOM 2088 N N . LYS A 1 269 ? -75.922 38.242 -43.364 1.00 39.93 ? 270 LYS A N 1 ATOM 2089 C CA . LYS A 1 269 ? -75.595 36.870 -43.023 1.00 41.68 ? 270 LYS A CA 1 ATOM 2090 C C . LYS A 1 269 ? -74.072 36.799 -42.850 1.00 39.22 ? 270 LYS A C 1 ATOM 2091 O O . LYS A 1 269 ? -73.321 37.617 -43.420 1.00 35.57 ? 270 LYS A O 1 ATOM 2092 C CB . LYS A 1 269 ? -76.090 35.891 -44.096 1.00 49.46 ? 270 LYS A CB 1 ATOM 2093 C CG . LYS A 1 269 ? -77.592 35.650 -44.032 1.00 58.81 ? 270 LYS A CG 1 ATOM 2094 C CD . LYS A 1 269 ? -78.242 35.448 -45.399 1.00 69.71 ? 270 LYS A CD 1 ATOM 2095 C CE . LYS A 1 269 ? -79.755 35.752 -45.318 1.00 83.72 ? 270 LYS A CE 1 ATOM 2096 N NZ . LYS A 1 269 ? -80.497 35.600 -46.615 1.00 85.60 ? 270 LYS A NZ 1 ATOM 2097 N N . PRO A 1 270 ? -73.604 35.816 -42.089 1.00 35.27 ? 271 PRO A N 1 ATOM 2098 C CA . PRO A 1 270 ? -72.156 35.725 -41.876 1.00 34.14 ? 271 PRO A CA 1 ATOM 2099 C C . PRO A 1 270 ? -71.376 35.741 -43.191 1.00 33.17 ? 271 PRO A C 1 ATOM 2100 O O . PRO A 1 270 ? -70.436 36.516 -43.359 1.00 31.80 ? 271 PRO A O 1 ATOM 2101 C CB . PRO A 1 270 ? -71.997 34.387 -41.132 1.00 36.72 ? 271 PRO A CB 1 ATOM 2102 C CG . PRO A 1 270 ? -73.346 34.186 -40.427 1.00 37.24 ? 271 PRO A CG 1 ATOM 2103 C CD . PRO A 1 270 ? -74.389 34.901 -41.233 1.00 32.57 ? 271 PRO A CD 1 ATOM 2104 N N . GLN A 1 271 ? -71.821 34.962 -44.158 1.00 38.30 ? 272 GLN A N 1 ATOM 2105 C CA . GLN A 1 271 ? -71.028 34.770 -45.364 1.00 42.24 ? 272 GLN A CA 1 ATOM 2106 C C . GLN A 1 271 ? -70.909 36.034 -46.219 1.00 39.09 ? 272 GLN A C 1 ATOM 2107 O O . GLN A 1 271 ? -69.934 36.206 -46.943 1.00 37.06 ? 272 GLN A O 1 ATOM 2108 C CB . GLN A 1 271 ? -71.534 33.581 -46.175 1.00 43.86 ? 272 GLN A CB 1 ATOM 2109 C CG . GLN A 1 271 ? -70.570 33.079 -47.267 1.00 42.86 ? 272 GLN A CG 1 ATOM 2110 C CD . GLN A 1 271 ? -69.179 32.756 -46.770 1.00 46.07 ? 272 GLN A CD 1 ATOM 2111 O OE1 . GLN A 1 271 ? -69.022 32.073 -45.758 1.00 44.38 ? 272 GLN A OE1 1 ATOM 2112 N NE2 . GLN A 1 271 ? -68.141 33.248 -47.497 1.00 44.88 ? 272 GLN A NE2 1 ATOM 2113 N N . GLU A 1 272 ? -71.837 36.956 -46.044 1.00 37.17 ? 273 GLU A N 1 ATOM 2114 C CA . GLU A 1 272 ? -71.797 38.252 -46.740 1.00 35.32 ? 273 GLU A CA 1 ATOM 2115 C C . GLU A 1 272 ? -70.671 39.071 -46.223 1.00 35.38 ? 273 GLU A C 1 ATOM 2116 O O . GLU A 1 272 ? -70.072 39.809 -46.979 1.00 41.78 ? 273 GLU A O 1 ATOM 2117 C CB . GLU A 1 272 ? -73.118 39.031 -46.530 1.00 35.65 ? 273 GLU A CB 1 ATOM 2118 C CG . GLU A 1 272 ? -74.336 38.203 -46.955 1.00 43.10 ? 273 GLU A CG 1 ATOM 2119 C CD . GLU A 1 272 ? -75.668 38.959 -46.861 1.00 44.64 ? 273 GLU A CD 1 ATOM 2120 O OE1 . GLU A 1 272 ? -75.843 40.001 -47.492 1.00 41.00 ? 273 GLU A OE1 1 ATOM 2121 O OE2 . GLU A 1 272 ? -76.550 38.469 -46.181 1.00 46.09 ? 273 GLU A OE2 1 ATOM 2122 N N . LEU A 1 273 ? -70.366 38.940 -44.926 1.00 32.32 ? 274 LEU A N 1 ATOM 2123 C CA . LEU A 1 273 ? -69.264 39.698 -44.360 1.00 32.93 ? 274 LEU A CA 1 ATOM 2124 C C . LEU A 1 273 ? -67.971 39.055 -44.808 1.00 28.97 ? 274 LEU A C 1 ATOM 2125 O O . LEU A 1 273 ? -67.055 39.731 -45.197 1.00 26.69 ? 274 LEU A O 1 ATOM 2126 C CB . LEU A 1 273 ? -69.331 39.785 -42.821 1.00 36.65 ? 274 LEU A CB 1 ATOM 2127 C CG . LEU A 1 273 ? -70.131 40.874 -42.067 1.00 37.45 ? 274 LEU A CG 1 ATOM 2128 C CD1 . LEU A 1 273 ? -71.524 41.015 -42.535 1.00 38.54 ? 274 LEU A CD1 1 ATOM 2129 C CD2 . LEU A 1 273 ? -70.203 40.572 -40.581 1.00 41.84 ? 274 LEU A CD2 1 ATOM 2130 N N . ILE A 1 274 ? -67.911 37.740 -44.744 1.00 29.59 ? 275 ILE A N 1 ATOM 2131 C CA . ILE A 1 274 ? -66.688 37.004 -45.102 1.00 32.17 ? 275 ILE A CA 1 ATOM 2132 C C . ILE A 1 274 ? -66.287 37.242 -46.586 1.00 34.00 ? 275 ILE A C 1 ATOM 2133 O O . ILE A 1 274 ? -65.136 37.515 -46.872 1.00 32.70 ? 275 ILE A O 1 ATOM 2134 C CB . ILE A 1 274 ? -66.847 35.519 -44.792 1.00 30.53 ? 275 ILE A CB 1 ATOM 2135 C CG1 . ILE A 1 274 ? -66.897 35.343 -43.267 1.00 31.92 ? 275 ILE A CG1 1 ATOM 2136 C CG2 . ILE A 1 274 ? -65.739 34.691 -45.485 1.00 31.64 ? 275 ILE A CG2 1 ATOM 2137 C CD1 . ILE A 1 274 ? -67.508 34.050 -42.791 1.00 32.93 ? 275 ILE A CD1 1 ATOM 2138 N N . ASP A 1 275 ? -67.277 37.306 -47.471 1.00 34.38 ? 276 ASP A N 1 ATOM 2139 C CA . ASP A 1 275 ? -67.045 37.466 -48.911 1.00 30.56 ? 276 ASP A CA 1 ATOM 2140 C C . ASP A 1 275 ? -66.375 38.765 -49.283 1.00 31.36 ? 276 ASP A C 1 ATOM 2141 O O . ASP A 1 275 ? -65.697 38.774 -50.257 1.00 31.04 ? 276 ASP A O 1 ATOM 2142 C CB . ASP A 1 275 ? -68.386 37.407 -49.670 1.00 31.78 ? 276 ASP A CB 1 ATOM 2143 C CG . ASP A 1 275 ? -68.857 36.020 -49.902 1.00 31.29 ? 276 ASP A CG 1 ATOM 2144 O OD1 . ASP A 1 275 ? -68.104 35.034 -49.674 1.00 39.30 ? 276 ASP A OD1 1 ATOM 2145 O OD2 . ASP A 1 275 ? -70.009 35.896 -50.272 1.00 37.43 ? 276 ASP A OD2 1 ATOM 2146 N N . VAL A 1 276 ? -66.575 39.854 -48.537 1.00 30.67 ? 277 VAL A N 1 ATOM 2147 C CA . VAL A 1 276 ? -65.969 41.162 -48.859 1.00 27.89 ? 277 VAL A CA 1 ATOM 2148 C C . VAL A 1 276 ? -64.849 41.611 -47.928 1.00 27.23 ? 277 VAL A C 1 ATOM 2149 O O . VAL A 1 276 ? -64.260 42.729 -48.078 1.00 26.08 ? 277 VAL A O 1 ATOM 2150 C CB . VAL A 1 276 ? -67.060 42.262 -48.876 1.00 33.55 ? 277 VAL A CB 1 ATOM 2151 C CG1 . VAL A 1 276 ? -68.011 42.019 -50.068 1.00 33.34 ? 277 VAL A CG1 1 ATOM 2152 C CG2 . VAL A 1 276 ? -67.856 42.292 -47.559 1.00 32.43 ? 277 VAL A CG2 1 ATOM 2153 N N . GLU A 1 277 ? -64.482 40.725 -46.997 1.00 25.89 ? 278 GLU A N 1 ATOM 2154 C CA . GLU A 1 277 ? -63.531 41.073 -45.867 1.00 23.28 ? 278 GLU A CA 1 ATOM 2155 C C . GLU A 1 277 ? -62.135 41.525 -46.359 1.00 26.19 ? 278 GLU A C 1 ATOM 2156 O O . GLU A 1 277 ? -61.444 42.372 -45.765 1.00 25.32 ? 278 GLU A O 1 ATOM 2157 C CB . GLU A 1 277 ? -63.430 39.785 -45.016 1.00 25.74 ? 278 GLU A CB 1 ATOM 2158 C CG . GLU A 1 277 ? -62.414 39.781 -43.917 1.00 27.98 ? 278 GLU A CG 1 ATOM 2159 C CD . GLU A 1 277 ? -62.274 38.476 -43.153 1.00 28.82 ? 278 GLU A CD 1 ATOM 2160 O OE1 . GLU A 1 277 ? -63.179 37.644 -43.081 1.00 31.21 ? 278 GLU A OE1 1 ATOM 2161 O OE2 . GLU A 1 277 ? -61.163 38.278 -42.635 1.00 36.51 ? 278 GLU A OE2 1 ATOM 2162 N N . TRP A 1 278 ? -61.665 40.907 -47.441 1.00 26.27 ? 279 TRP A N 1 ATOM 2163 C CA . TRP A 1 278 ? -60.328 41.202 -47.948 1.00 24.35 ? 279 TRP A CA 1 ATOM 2164 C C . TRP A 1 278 ? -60.353 42.443 -48.710 1.00 25.28 ? 279 TRP A C 1 ATOM 2165 O O . TRP A 1 278 ? -59.314 43.012 -48.905 1.00 35.01 ? 279 TRP A O 1 ATOM 2166 C CB . TRP A 1 278 ? -59.813 40.071 -48.758 1.00 28.01 ? 279 TRP A CB 1 ATOM 2167 C CG . TRP A 1 278 ? -59.743 38.863 -47.959 1.00 32.03 ? 279 TRP A CG 1 ATOM 2168 C CD1 . TRP A 1 278 ? -60.687 37.882 -47.879 1.00 33.95 ? 279 TRP A CD1 1 ATOM 2169 C CD2 . TRP A 1 278 ? -58.720 38.531 -47.013 1.00 30.23 ? 279 TRP A CD2 1 ATOM 2170 N NE1 . TRP A 1 278 ? -60.294 36.912 -46.962 1.00 38.02 ? 279 TRP A NE1 1 ATOM 2171 C CE2 . TRP A 1 278 ? -59.078 37.288 -46.430 1.00 36.93 ? 279 TRP A CE2 1 ATOM 2172 C CE3 . TRP A 1 278 ? -57.518 39.112 -46.668 1.00 38.01 ? 279 TRP A CE3 1 ATOM 2173 C CZ2 . TRP A 1 278 ? -58.276 36.637 -45.504 1.00 39.58 ? 279 TRP A CZ2 1 ATOM 2174 C CZ3 . TRP A 1 278 ? -56.677 38.437 -45.739 1.00 45.24 ? 279 TRP A CZ3 1 ATOM 2175 C CH2 . TRP A 1 278 ? -57.073 37.209 -45.173 1.00 40.34 ? 279 TRP A CH2 1 ATOM 2176 N N . ASN A 1 279 ? -61.535 42.999 -48.987 1.00 28.59 ? 280 ASN A N 1 ATOM 2177 C CA . ASN A 1 279 ? -61.568 44.293 -49.732 1.00 28.56 ? 280 ASN A CA 1 ATOM 2178 C C . ASN A 1 279 ? -61.216 45.521 -48.973 1.00 27.90 ? 280 ASN A C 1 ATOM 2179 O O . ASN A 1 279 ? -61.099 46.581 -49.576 1.00 30.09 ? 280 ASN A O 1 ATOM 2180 C CB . ASN A 1 279 ? -62.923 44.515 -50.405 1.00 27.76 ? 280 ASN A CB 1 ATOM 2181 C CG . ASN A 1 279 ? -63.346 43.339 -51.294 1.00 30.85 ? 280 ASN A CG 1 ATOM 2182 O OD1 . ASN A 1 279 ? -62.531 42.500 -51.692 1.00 32.11 ? 280 ASN A OD1 1 ATOM 2183 N ND2 . ASN A 1 279 ? -64.621 43.268 -51.592 1.00 31.18 ? 280 ASN A ND2 1 ATOM 2184 N N . VAL A 1 280 ? -60.986 45.438 -47.674 1.00 29.61 ? 281 VAL A N 1 ATOM 2185 C CA . VAL A 1 280 ? -60.814 46.689 -46.873 1.00 28.99 ? 281 VAL A CA 1 ATOM 2186 C C . VAL A 1 280 ? -59.384 47.022 -46.548 1.00 27.82 ? 281 VAL A C 1 ATOM 2187 O O . VAL A 1 280 ? -59.094 47.991 -45.816 1.00 27.54 ? 281 VAL A O 1 ATOM 2188 C CB . VAL A 1 280 ? -61.638 46.663 -45.548 1.00 29.17 ? 281 VAL A CB 1 ATOM 2189 C CG1 . VAL A 1 280 ? -63.115 46.295 -45.862 1.00 30.02 ? 281 VAL A CG1 1 ATOM 2190 C CG2 . VAL A 1 280 ? -61.079 45.665 -44.520 1.00 29.32 ? 281 VAL A CG2 1 ATOM 2191 N N . LEU A 1 281 ? -58.477 46.180 -47.006 1.00 27.14 ? 282 LEU A N 1 ATOM 2192 C CA . LEU A 1 281 ? -57.044 46.358 -46.636 1.00 27.93 ? 282 LEU A CA 1 ATOM 2193 C C . LEU A 1 281 ? -56.549 47.581 -47.349 1.00 29.85 ? 282 LEU A C 1 ATOM 2194 O O . LEU A 1 281 ? -56.924 47.825 -48.501 1.00 31.56 ? 282 LEU A O 1 ATOM 2195 C CB . LEU A 1 281 ? -56.179 45.181 -47.088 1.00 29.35 ? 282 LEU A CB 1 ATOM 2196 C CG . LEU A 1 281 ? -56.376 43.921 -46.270 1.00 31.37 ? 282 LEU A CG 1 ATOM 2197 C CD1 . LEU A 1 281 ? -55.624 42.812 -46.972 1.00 33.17 ? 282 LEU A CD1 1 ATOM 2198 C CD2 . LEU A 1 281 ? -55.812 44.125 -44.856 1.00 30.76 ? 282 LEU A CD2 1 ATOM 2199 N N . PRO A 1 282 ? -55.694 48.338 -46.696 1.00 29.32 ? 283 PRO A N 1 ATOM 2200 C CA . PRO A 1 282 ? -55.386 49.639 -47.265 1.00 31.80 ? 283 PRO A CA 1 ATOM 2201 C C . PRO A 1 282 ? -54.349 49.559 -48.379 1.00 34.37 ? 283 PRO A C 1 ATOM 2202 O O . PRO A 1 282 ? -54.271 50.480 -49.179 1.00 34.13 ? 283 PRO A O 1 ATOM 2203 C CB . PRO A 1 282 ? -54.827 50.436 -46.045 1.00 30.57 ? 283 PRO A CB 1 ATOM 2204 C CG . PRO A 1 282 ? -54.309 49.373 -45.134 1.00 31.12 ? 283 PRO A CG 1 ATOM 2205 C CD . PRO A 1 282 ? -55.178 48.175 -45.328 1.00 29.43 ? 283 PRO A CD 1 ATOM 2206 N N . PHE A 1 283 ? -53.527 48.498 -48.370 1.00 36.02 ? 284 PHE A N 1 ATOM 2207 C CA . PHE A 1 283 ? -52.477 48.267 -49.355 1.00 34.82 ? 284 PHE A CA 1 ATOM 2208 C C . PHE A 1 283 ? -52.563 46.895 -50.019 1.00 34.02 ? 284 PHE A C 1 ATOM 2209 O O . PHE A 1 283 ? -53.162 45.928 -49.525 1.00 29.87 ? 284 PHE A O 1 ATOM 2210 C CB . PHE A 1 283 ? -51.081 48.369 -48.728 1.00 37.69 ? 284 PHE A CB 1 ATOM 2211 C CG . PHE A 1 283 ? -50.898 49.562 -47.851 1.00 44.10 ? 284 PHE A CG 1 ATOM 2212 C CD1 . PHE A 1 283 ? -50.760 50.842 -48.404 1.00 46.11 ? 284 PHE A CD1 1 ATOM 2213 C CD2 . PHE A 1 283 ? -50.896 49.419 -46.437 1.00 50.66 ? 284 PHE A CD2 1 ATOM 2214 C CE1 . PHE A 1 283 ? -50.609 51.959 -47.570 1.00 50.70 ? 284 PHE A CE1 1 ATOM 2215 C CE2 . PHE A 1 283 ? -50.734 50.521 -45.599 1.00 46.16 ? 284 PHE A CE2 1 ATOM 2216 C CZ . PHE A 1 283 ? -50.596 51.797 -46.164 1.00 49.58 ? 284 PHE A CZ 1 ATOM 2217 N N . ASP A 1 284 ? -51.873 46.820 -51.144 1.00 34.40 ? 285 ASP A N 1 ATOM 2218 C CA . ASP A 1 284 ? -51.618 45.571 -51.818 1.00 31.62 ? 285 ASP A CA 1 ATOM 2219 C C . ASP A 1 284 ? -50.443 44.943 -51.070 1.00 28.58 ? 285 ASP A C 1 ATOM 2220 O O . ASP A 1 284 ? -49.270 45.425 -51.091 1.00 30.61 ? 285 ASP A O 1 ATOM 2221 C CB . ASP A 1 284 ? -51.244 45.884 -53.269 1.00 33.19 ? 285 ASP A CB 1 ATOM 2222 C CG . ASP A 1 284 ? -51.119 44.668 -54.098 1.00 34.01 ? 285 ASP A CG 1 ATOM 2223 O OD1 . ASP A 1 284 ? -51.532 43.579 -53.638 1.00 33.01 ? 285 ASP A OD1 1 ATOM 2224 O OD2 . ASP A 1 284 ? -50.617 44.818 -55.227 1.00 37.52 ? 285 ASP A OD2 1 ATOM 2225 N N . SER A 1 285 ? -50.752 43.899 -50.360 1.00 25.51 ? 286 SER A N 1 ATOM 2226 C CA . SER A 1 285 ? -49.819 43.403 -49.360 1.00 26.38 ? 286 SER A CA 1 ATOM 2227 C C . SER A 1 285 ? -49.974 41.913 -49.233 1.00 26.12 ? 286 SER A C 1 ATOM 2228 O O . SER A 1 285 ? -50.961 41.341 -49.678 1.00 25.13 ? 286 SER A O 1 ATOM 2229 C CB . SER A 1 285 ? -50.163 44.076 -48.018 1.00 28.58 ? 286 SER A CB 1 ATOM 2230 O OG . SER A 1 285 ? -51.543 43.785 -47.673 1.00 29.46 ? 286 SER A OG 1 ATOM 2231 N N . ILE A 1 286 ? -48.984 41.279 -48.636 1.00 26.69 ? 287 ILE A N 1 ATOM 2232 C CA . ILE A 1 286 ? -49.178 39.995 -48.069 1.00 24.51 ? 287 ILE A CA 1 ATOM 2233 C C . ILE A 1 286 ? -48.849 40.027 -46.569 1.00 25.24 ? 287 ILE A C 1 ATOM 2234 O O . ILE A 1 286 ? -48.145 40.945 -46.064 1.00 25.76 ? 287 ILE A O 1 ATOM 2235 C CB . ILE A 1 286 ? -48.271 38.999 -48.739 1.00 26.08 ? 287 ILE A CB 1 ATOM 2236 C CG1 . ILE A 1 286 ? -46.842 39.364 -48.523 1.00 25.87 ? 287 ILE A CG1 1 ATOM 2237 C CG2 . ILE A 1 286 ? -48.569 38.904 -50.213 1.00 30.75 ? 287 ILE A CG2 1 ATOM 2238 C CD1 . ILE A 1 286 ? -45.924 38.325 -49.115 1.00 27.79 ? 287 ILE A CD1 1 ATOM 2239 N N . PHE A 1 287 ? -49.279 38.985 -45.882 1.00 24.69 ? 288 PHE A N 1 ATOM 2240 C CA . PHE A 1 287 ? -49.178 38.910 -44.401 1.00 25.72 ? 288 PHE A CA 1 ATOM 2241 C C . PHE A 1 287 ? -49.866 40.073 -43.694 1.00 24.26 ? 288 PHE A C 1 ATOM 2242 O O . PHE A 1 287 ? -49.337 40.636 -42.746 1.00 25.55 ? 288 PHE A O 1 ATOM 2243 C CB . PHE A 1 287 ? -47.714 38.844 -43.966 1.00 25.13 ? 288 PHE A CB 1 ATOM 2244 C CG . PHE A 1 287 ? -47.435 37.813 -42.888 1.00 28.44 ? 288 PHE A CG 1 ATOM 2245 C CD1 . PHE A 1 287 ? -48.211 37.744 -41.726 1.00 26.62 ? 288 PHE A CD1 1 ATOM 2246 C CD2 . PHE A 1 287 ? -46.337 36.981 -42.992 1.00 26.90 ? 288 PHE A CD2 1 ATOM 2247 C CE1 . PHE A 1 287 ? -47.903 36.848 -40.724 1.00 29.34 ? 288 PHE A CE1 1 ATOM 2248 C CE2 . PHE A 1 287 ? -46.053 36.071 -42.001 1.00 27.96 ? 288 PHE A CE2 1 ATOM 2249 C CZ . PHE A 1 287 ? -46.849 35.996 -40.855 1.00 28.99 ? 288 PHE A CZ 1 ATOM 2250 N N . ARG A 1 288 ? -50.995 40.488 -44.225 1.00 27.44 ? 289 ARG A N 1 ATOM 2251 C CA . ARG A 1 288 ? -51.828 41.516 -43.612 1.00 27.00 ? 289 ARG A CA 1 ATOM 2252 C C . ARG A 1 288 ? -53.272 41.045 -43.644 1.00 28.51 ? 289 ARG A C 1 ATOM 2253 O O . ARG A 1 288 ? -53.739 40.475 -44.649 1.00 29.42 ? 289 ARG A O 1 ATOM 2254 C CB . ARG A 1 288 ? -51.688 42.872 -44.271 1.00 26.42 ? 289 ARG A CB 1 ATOM 2255 C CG . ARG A 1 288 ? -50.315 43.470 -44.170 1.00 27.95 ? 289 ARG A CG 1 ATOM 2256 C CD . ARG A 1 288 ? -49.916 43.814 -42.750 1.00 29.64 ? 289 ARG A CD 1 ATOM 2257 N NE . ARG A 1 288 ? -48.637 44.504 -42.690 1.00 28.66 ? 289 ARG A NE 1 ATOM 2258 C CZ . ARG A 1 288 ? -47.444 43.939 -42.660 1.00 29.41 ? 289 ARG A CZ 1 ATOM 2259 N NH1 . ARG A 1 288 ? -47.333 42.623 -42.673 1.00 32.99 ? 289 ARG A NH1 1 ATOM 2260 N NH2 . ARG A 1 288 ? -46.352 44.704 -42.587 1.00 30.22 ? 289 ARG A NH2 1 ATOM 2261 N N . PHE A 1 289 ? -53.950 41.245 -42.506 1.00 26.99 ? 290 PHE A N 1 ATOM 2262 C CA . PHE A 1 289 ? -55.296 40.778 -42.326 1.00 25.53 ? 290 PHE A CA 1 ATOM 2263 C C . PHE A 1 289 ? -56.186 41.963 -41.923 1.00 23.91 ? 290 PHE A C 1 ATOM 2264 O O . PHE A 1 289 ? -55.771 42.902 -41.286 1.00 28.27 ? 290 PHE A O 1 ATOM 2265 C CB . PHE A 1 289 ? -55.303 39.617 -41.295 1.00 25.81 ? 290 PHE A CB 1 ATOM 2266 C CG . PHE A 1 289 ? -54.102 38.698 -41.426 1.00 25.38 ? 290 PHE A CG 1 ATOM 2267 C CD1 . PHE A 1 289 ? -53.944 37.881 -42.545 1.00 24.58 ? 290 PHE A CD1 1 ATOM 2268 C CD2 . PHE A 1 289 ? -53.092 38.702 -40.489 1.00 25.36 ? 290 PHE A CD2 1 ATOM 2269 C CE1 . PHE A 1 289 ? -52.794 37.073 -42.720 1.00 24.27 ? 290 PHE A CE1 1 ATOM 2270 C CE2 . PHE A 1 289 ? -51.966 37.890 -40.627 1.00 25.26 ? 290 PHE A CE2 1 ATOM 2271 C CZ . PHE A 1 289 ? -51.828 37.054 -41.752 1.00 26.48 ? 290 PHE A CZ 1 ATOM 2272 N N . SER A 1 290 ? -57.424 41.862 -42.279 1.00 26.54 ? 291 SER A N 1 ATOM 2273 C CA . SER A 1 290 ? -58.357 42.955 -42.232 1.00 32.37 ? 291 SER A CA 1 ATOM 2274 C C . SER A 1 290 ? -58.764 43.333 -40.777 1.00 32.19 ? 291 SER A C 1 ATOM 2275 O O . SER A 1 290 ? -58.585 44.484 -40.387 1.00 25.34 ? 291 SER A O 1 ATOM 2276 C CB . SER A 1 290 ? -59.611 42.638 -43.079 1.00 30.11 ? 291 SER A CB 1 ATOM 2277 O OG . SER A 1 290 ? -59.251 42.383 -44.423 1.00 32.72 ? 291 SER A OG 1 ATOM 2278 N N . PHE A 1 291 ? -59.258 42.354 -40.018 1.00 28.92 ? 292 PHE A N 1 ATOM 2279 C CA . PHE A 1 291 ? -59.795 42.617 -38.647 1.00 27.32 ? 292 PHE A CA 1 ATOM 2280 C C . PHE A 1 291 ? -58.952 41.930 -37.577 1.00 25.02 ? 292 PHE A C 1 ATOM 2281 O O . PHE A 1 291 ? -59.044 40.736 -37.381 1.00 22.44 ? 292 PHE A O 1 ATOM 2282 C CB . PHE A 1 291 ? -61.255 42.159 -38.579 1.00 27.24 ? 292 PHE A CB 1 ATOM 2283 C CG . PHE A 1 291 ? -62.110 42.886 -39.570 1.00 26.64 ? 292 PHE A CG 1 ATOM 2284 C CD1 . PHE A 1 291 ? -62.422 44.236 -39.381 1.00 28.14 ? 292 PHE A CD1 1 ATOM 2285 C CD2 . PHE A 1 291 ? -62.446 42.281 -40.785 1.00 28.78 ? 292 PHE A CD2 1 ATOM 2286 C CE1 . PHE A 1 291 ? -63.135 44.957 -40.351 1.00 26.21 ? 292 PHE A CE1 1 ATOM 2287 C CE2 . PHE A 1 291 ? -63.130 42.999 -41.756 1.00 29.14 ? 292 PHE A CE2 1 ATOM 2288 C CZ . PHE A 1 291 ? -63.491 44.326 -41.519 1.00 29.21 ? 292 PHE A CZ 1 ATOM 2289 N N . VAL A 1 292 ? -58.103 42.739 -36.963 1.00 24.50 ? 293 VAL A N 1 ATOM 2290 C CA . VAL A 1 292 ? -57.179 42.380 -35.962 1.00 23.17 ? 293 VAL A CA 1 ATOM 2291 C C . VAL A 1 292 ? -57.335 43.273 -34.673 1.00 26.69 ? 293 VAL A C 1 ATOM 2292 O O . VAL A 1 292 ? -58.104 44.238 -34.660 1.00 25.60 ? 293 VAL A O 1 ATOM 2293 C CB . VAL A 1 292 ? -55.799 42.563 -36.530 1.00 22.29 ? 293 VAL A CB 1 ATOM 2294 C CG1 . VAL A 1 292 ? -55.581 41.671 -37.718 1.00 23.43 ? 293 VAL A CG1 1 ATOM 2295 C CG2 . VAL A 1 292 ? -55.523 43.998 -36.883 1.00 22.98 ? 293 VAL A CG2 1 ATOM 2296 N N . PRO A 1 293 ? -56.642 42.922 -33.566 1.00 25.14 ? 294 PRO A N 1 ATOM 2297 C CA . PRO A 1 293 ? -56.701 43.710 -32.364 1.00 25.46 ? 294 PRO A CA 1 ATOM 2298 C C . PRO A 1 293 ? -56.430 45.203 -32.624 1.00 27.19 ? 294 PRO A C 1 ATOM 2299 O O . PRO A 1 293 ? -55.639 45.512 -33.507 1.00 25.67 ? 294 PRO A O 1 ATOM 2300 C CB . PRO A 1 293 ? -55.585 43.116 -31.522 1.00 24.21 ? 294 PRO A CB 1 ATOM 2301 C CG . PRO A 1 293 ? -55.647 41.696 -31.844 1.00 26.05 ? 294 PRO A CG 1 ATOM 2302 C CD . PRO A 1 293 ? -55.999 41.634 -33.315 1.00 26.17 ? 294 PRO A CD 1 ATOM 2303 N N . VAL A 1 294 ? -57.071 46.072 -31.847 1.00 26.40 ? 295 VAL A N 1 ATOM 2304 C CA . VAL A 1 294 ? -56.875 47.511 -31.952 1.00 30.19 ? 295 VAL A CA 1 ATOM 2305 C C . VAL A 1 294 ? -56.350 48.088 -30.639 1.00 30.69 ? 295 VAL A C 1 ATOM 2306 O O . VAL A 1 294 ? -56.825 47.743 -29.557 1.00 26.58 ? 295 VAL A O 1 ATOM 2307 C CB . VAL A 1 294 ? -58.182 48.232 -32.333 1.00 35.69 ? 295 VAL A CB 1 ATOM 2308 C CG1 . VAL A 1 294 ? -58.413 48.151 -33.834 1.00 44.71 ? 295 VAL A CG1 1 ATOM 2309 C CG2 . VAL A 1 294 ? -59.357 47.638 -31.572 1.00 36.43 ? 295 VAL A CG2 1 ATOM 2310 N N . ILE A 1 295 ? -55.363 48.969 -30.753 1.00 26.58 ? 296 ILE A N 1 ATOM 2311 C CA . ILE A 1 295 ? -54.746 49.601 -29.631 1.00 28.15 ? 296 ILE A CA 1 ATOM 2312 C C . ILE A 1 295 ? -55.729 50.676 -29.168 1.00 31.61 ? 296 ILE A C 1 ATOM 2313 O O . ILE A 1 295 ? -55.751 51.828 -29.729 1.00 27.69 ? 296 ILE A O 1 ATOM 2314 C CB . ILE A 1 295 ? -53.413 50.192 -30.054 1.00 29.61 ? 296 ILE A CB 1 ATOM 2315 C CG1 . ILE A 1 295 ? -52.535 49.084 -30.708 1.00 28.62 ? 296 ILE A CG1 1 ATOM 2316 C CG2 . ILE A 1 295 ? -52.694 50.783 -28.859 1.00 30.96 ? 296 ILE A CG2 1 ATOM 2317 C CD1 . ILE A 1 295 ? -52.332 47.805 -29.895 1.00 27.28 ? 296 ILE A CD1 1 ATOM 2318 N N . ASP A 1 296 ? -56.577 50.253 -28.200 1.00 27.08 ? 297 ASP A N 1 ATOM 2319 C CA . ASP A 1 296 ? -57.822 50.942 -27.839 1.00 29.86 ? 297 ASP A CA 1 ATOM 2320 C C . ASP A 1 296 ? -57.735 51.832 -26.589 1.00 32.48 ? 297 ASP A C 1 ATOM 2321 O O . ASP A 1 296 ? -58.670 52.569 -26.327 1.00 36.32 ? 297 ASP A O 1 ATOM 2322 C CB . ASP A 1 296 ? -58.992 49.957 -27.592 1.00 28.18 ? 297 ASP A CB 1 ATOM 2323 C CG . ASP A 1 296 ? -58.658 48.929 -26.540 1.00 29.95 ? 297 ASP A CG 1 ATOM 2324 O OD1 . ASP A 1 296 ? -57.452 48.852 -26.153 1.00 29.02 ? 297 ASP A OD1 1 ATOM 2325 O OD2 . ASP A 1 296 ? -59.554 48.189 -26.118 1.00 33.79 ? 297 ASP A OD2 1 ATOM 2326 N N . GLY A 1 297 ? -56.676 51.722 -25.807 1.00 36.46 ? 298 GLY A N 1 ATOM 2327 C CA . GLY A 1 297 ? -56.611 52.395 -24.509 1.00 39.78 ? 298 GLY A CA 1 ATOM 2328 C C . GLY A 1 297 ? -57.289 51.643 -23.348 1.00 42.83 ? 298 GLY A C 1 ATOM 2329 O O . GLY A 1 297 ? -57.361 52.166 -22.275 1.00 40.35 ? 298 GLY A O 1 ATOM 2330 N N . GLU A 1 298 ? -57.780 50.427 -23.559 1.00 37.05 ? 299 GLU A N 1 ATOM 2331 C CA . GLU A 1 298 ? -58.507 49.697 -22.543 1.00 39.29 ? 299 GLU A CA 1 ATOM 2332 C C . GLU A 1 298 ? -57.835 48.323 -22.354 1.00 33.40 ? 299 GLU A C 1 ATOM 2333 O O . GLU A 1 298 ? -57.084 48.096 -21.406 1.00 29.16 ? 299 GLU A O 1 ATOM 2334 C CB . GLU A 1 298 ? -59.985 49.552 -22.955 1.00 46.56 ? 299 GLU A CB 1 ATOM 2335 C CG . GLU A 1 298 ? -60.944 50.533 -22.280 1.00 62.96 ? 299 GLU A CG 1 ATOM 2336 C CD . GLU A 1 298 ? -61.928 51.238 -23.242 1.00 72.72 ? 299 GLU A CD 1 ATOM 2337 O OE1 . GLU A 1 298 ? -62.366 50.661 -24.268 1.00 69.95 ? 299 GLU A OE1 1 ATOM 2338 O OE2 . GLU A 1 298 ? -62.280 52.404 -22.956 1.00 84.27 ? 299 GLU A OE2 1 ATOM 2339 N N . PHE A 1 299 ? -58.052 47.432 -23.310 1.00 29.06 ? 300 PHE A N 1 ATOM 2340 C CA . PHE A 1 299 ? -57.348 46.195 -23.342 1.00 26.74 ? 300 PHE A CA 1 ATOM 2341 C C . PHE A 1 299 ? -55.841 46.459 -23.368 1.00 28.58 ? 300 PHE A C 1 ATOM 2342 O O . PHE A 1 299 ? -55.072 45.803 -22.623 1.00 25.91 ? 300 PHE A O 1 ATOM 2343 C CB . PHE A 1 299 ? -57.881 45.359 -24.512 1.00 27.93 ? 300 PHE A CB 1 ATOM 2344 C CG . PHE A 1 299 ? -57.454 43.952 -24.459 1.00 28.07 ? 300 PHE A CG 1 ATOM 2345 C CD1 . PHE A 1 299 ? -56.123 43.618 -24.741 1.00 26.34 ? 300 PHE A CD1 1 ATOM 2346 C CD2 . PHE A 1 299 ? -58.346 42.956 -24.063 1.00 27.61 ? 300 PHE A CD2 1 ATOM 2347 C CE1 . PHE A 1 299 ? -55.717 42.319 -24.666 1.00 24.05 ? 300 PHE A CE1 1 ATOM 2348 C CE2 . PHE A 1 299 ? -57.931 41.643 -23.993 1.00 22.77 ? 300 PHE A CE2 1 ATOM 2349 C CZ . PHE A 1 299 ? -56.619 41.348 -24.282 1.00 24.37 ? 300 PHE A CZ 1 ATOM 2350 N N . PHE A 1 300 ? -55.416 47.433 -24.193 1.00 30.19 ? 301 PHE A N 1 ATOM 2351 C CA . PHE A 1 300 ? -54.023 47.884 -24.225 1.00 27.96 ? 301 PHE A CA 1 ATOM 2352 C C . PHE A 1 300 ? -54.040 49.344 -23.815 1.00 32.07 ? 301 PHE A C 1 ATOM 2353 O O . PHE A 1 300 ? -54.672 50.158 -24.496 1.00 31.95 ? 301 PHE A O 1 ATOM 2354 C CB . PHE A 1 300 ? -53.450 47.804 -25.618 1.00 26.57 ? 301 PHE A CB 1 ATOM 2355 C CG . PHE A 1 300 ? -53.565 46.452 -26.265 1.00 25.58 ? 301 PHE A CG 1 ATOM 2356 C CD1 . PHE A 1 300 ? -52.696 45.447 -25.945 1.00 24.82 ? 301 PHE A CD1 1 ATOM 2357 C CD2 . PHE A 1 300 ? -54.501 46.211 -27.209 1.00 26.40 ? 301 PHE A CD2 1 ATOM 2358 C CE1 . PHE A 1 300 ? -52.759 44.242 -26.553 1.00 26.06 ? 301 PHE A CE1 1 ATOM 2359 C CE2 . PHE A 1 300 ? -54.586 44.977 -27.830 1.00 24.74 ? 301 PHE A CE2 1 ATOM 2360 C CZ . PHE A 1 300 ? -53.725 43.987 -27.487 1.00 23.80 ? 301 PHE A CZ 1 ATOM 2361 N N . PRO A 1 301 ? -53.417 49.677 -22.682 1.00 31.91 ? 302 PRO A N 1 ATOM 2362 C CA . PRO A 1 301 ? -53.685 51.008 -22.159 1.00 34.78 ? 302 PRO A CA 1 ATOM 2363 C C . PRO A 1 301 ? -52.889 52.088 -22.872 1.00 33.48 ? 302 PRO A C 1 ATOM 2364 O O . PRO A 1 301 ? -53.340 53.214 -22.928 1.00 36.83 ? 302 PRO A O 1 ATOM 2365 C CB . PRO A 1 301 ? -53.321 50.888 -20.656 1.00 31.86 ? 302 PRO A CB 1 ATOM 2366 C CG . PRO A 1 301 ? -52.480 49.666 -20.547 1.00 37.77 ? 302 PRO A CG 1 ATOM 2367 C CD . PRO A 1 301 ? -53.009 48.749 -21.611 1.00 37.01 ? 302 PRO A CD 1 ATOM 2368 N N . THR A 1 302 ? -51.701 51.749 -23.363 1.00 34.61 ? 303 THR A N 1 ATOM 2369 C CA . THR A 1 302 ? -50.913 52.563 -24.271 1.00 31.96 ? 303 THR A CA 1 ATOM 2370 C C . THR A 1 302 ? -50.309 51.724 -25.420 1.00 33.51 ? 303 THR A C 1 ATOM 2371 O O . THR A 1 302 ? -50.510 50.519 -25.535 1.00 30.38 ? 303 THR A O 1 ATOM 2372 C CB . THR A 1 302 ? -49.781 53.269 -23.510 1.00 36.14 ? 303 THR A CB 1 ATOM 2373 O OG1 . THR A 1 302 ? -48.794 52.337 -23.025 1.00 35.22 ? 303 THR A OG1 1 ATOM 2374 C CG2 . THR A 1 302 ? -50.365 54.009 -22.324 1.00 39.81 ? 303 THR A CG2 1 ATOM 2375 N N . SER A 1 303 ? -49.467 52.362 -26.213 1.00 32.87 ? 304 SER A N 1 ATOM 2376 C CA . SER A 1 303 ? -48.902 51.700 -27.345 1.00 31.01 ? 304 SER A CA 1 ATOM 2377 C C . SER A 1 303 ? -48.163 50.479 -26.851 1.00 32.03 ? 304 SER A C 1 ATOM 2378 O O . SER A 1 303 ? -47.640 50.486 -25.725 1.00 30.85 ? 304 SER A O 1 ATOM 2379 C CB . SER A 1 303 ? -47.922 52.611 -28.081 1.00 29.93 ? 304 SER A CB 1 ATOM 2380 O OG . SER A 1 303 ? -46.756 52.784 -27.298 1.00 31.58 ? 304 SER A OG 1 ATOM 2381 N N . LEU A 1 304 ? -48.070 49.457 -27.720 1.00 30.22 ? 305 LEU A N 1 ATOM 2382 C CA . LEU A 1 304 ? -47.414 48.233 -27.300 1.00 30.84 ? 305 LEU A CA 1 ATOM 2383 C C . LEU A 1 304 ? -45.969 48.511 -26.950 1.00 32.24 ? 305 LEU A C 1 ATOM 2384 O O . LEU A 1 304 ? -45.446 47.947 -26.000 1.00 31.45 ? 305 LEU A O 1 ATOM 2385 C CB . LEU A 1 304 ? -47.491 47.147 -28.327 1.00 26.44 ? 305 LEU A CB 1 ATOM 2386 C CG . LEU A 1 304 ? -48.892 46.743 -28.729 1.00 28.08 ? 305 LEU A CG 1 ATOM 2387 C CD1 . LEU A 1 304 ? -48.835 45.618 -29.757 1.00 28.54 ? 305 LEU A CD1 1 ATOM 2388 C CD2 . LEU A 1 304 ? -49.812 46.411 -27.574 1.00 31.42 ? 305 LEU A CD2 1 ATOM 2389 N N . GLU A 1 305 ? -45.328 49.383 -27.716 1.00 29.29 ? 306 GLU A N 1 ATOM 2390 C CA . GLU A 1 305 ? -43.909 49.634 -27.534 1.00 30.33 ? 306 GLU A CA 1 ATOM 2391 C C . GLU A 1 305 ? -43.674 50.396 -26.216 1.00 32.29 ? 306 GLU A C 1 ATOM 2392 O O . GLU A 1 305 ? -42.685 50.173 -25.555 1.00 28.89 ? 306 GLU A O 1 ATOM 2393 C CB . GLU A 1 305 ? -43.379 50.458 -28.722 1.00 31.12 ? 306 GLU A CB 1 ATOM 2394 C CG . GLU A 1 305 ? -41.913 50.908 -28.658 1.00 33.33 ? 306 GLU A CG 1 ATOM 2395 C CD . GLU A 1 305 ? -40.911 49.759 -28.694 1.00 38.54 ? 306 GLU A CD 1 ATOM 2396 O OE1 . GLU A 1 305 ? -41.285 48.589 -28.979 1.00 39.17 ? 306 GLU A OE1 1 ATOM 2397 O OE2 . GLU A 1 305 ? -39.720 50.026 -28.433 1.00 42.57 ? 306 GLU A OE2 1 ATOM 2398 N N . SER A 1 306 ? -44.569 51.333 -25.851 1.00 34.01 ? 307 SER A N 1 ATOM 2399 C CA . SER A 1 306 ? -44.362 52.049 -24.586 1.00 32.04 ? 307 SER A CA 1 ATOM 2400 C C . SER A 1 306 ? -44.566 51.061 -23.378 1.00 32.57 ? 307 SER A C 1 ATOM 2401 O O . SER A 1 306 ? -43.771 51.091 -22.423 1.00 31.82 ? 307 SER A O 1 ATOM 2402 C CB . SER A 1 306 ? -45.208 53.320 -24.498 1.00 28.01 ? 307 SER A CB 1 ATOM 2403 O OG . SER A 1 306 ? -46.554 53.027 -24.232 1.00 37.85 ? 307 SER A OG 1 ATOM 2404 N N . MET A 1 307 ? -45.555 50.147 -23.457 1.00 28.24 ? 308 MET A N 1 ATOM 2405 C CA . MET A 1 307 ? -45.687 49.097 -22.425 1.00 29.49 ? 308 MET A CA 1 ATOM 2406 C C . MET A 1 307 ? -44.437 48.251 -22.373 1.00 30.28 ? 308 MET A C 1 ATOM 2407 O O . MET A 1 307 ? -43.926 47.955 -21.308 1.00 31.54 ? 308 MET A O 1 ATOM 2408 C CB . MET A 1 307 ? -46.935 48.216 -22.639 1.00 29.62 ? 308 MET A CB 1 ATOM 2409 C CG . MET A 1 307 ? -48.221 48.984 -22.638 1.00 27.28 ? 308 MET A CG 1 ATOM 2410 S SD . MET A 1 307 ? -49.680 47.998 -23.066 1.00 32.61 ? 308 MET A SD 1 ATOM 2411 C CE . MET A 1 307 ? -49.651 46.920 -21.596 1.00 34.76 ? 308 MET A CE 1 ATOM 2412 N N . LEU A 1 308 ? -43.889 47.875 -23.514 1.00 31.23 ? 309 LEU A N 1 ATOM 2413 C CA . LEU A 1 308 ? -42.715 47.017 -23.474 1.00 33.81 ? 309 LEU A CA 1 ATOM 2414 C C . LEU A 1 308 ? -41.512 47.686 -22.845 1.00 36.72 ? 309 LEU A C 1 ATOM 2415 O O . LEU A 1 308 ? -40.719 47.064 -22.079 1.00 38.65 ? 309 LEU A O 1 ATOM 2416 C CB . LEU A 1 308 ? -42.357 46.501 -24.875 1.00 35.41 ? 309 LEU A CB 1 ATOM 2417 C CG . LEU A 1 308 ? -43.278 45.364 -25.346 1.00 38.23 ? 309 LEU A CG 1 ATOM 2418 C CD1 . LEU A 1 308 ? -43.032 45.122 -26.809 1.00 38.49 ? 309 LEU A CD1 1 ATOM 2419 C CD2 . LEU A 1 308 ? -43.142 44.033 -24.598 1.00 32.98 ? 309 LEU A CD2 1 ATOM 2420 N N . ASN A 1 309 ? -41.358 48.955 -23.197 1.00 37.78 ? 310 ASN A N 1 ATOM 2421 C CA . ASN A 1 309 ? -40.290 49.794 -22.655 1.00 38.34 ? 310 ASN A CA 1 ATOM 2422 C C . ASN A 1 309 ? -40.360 50.073 -21.174 1.00 34.67 ? 310 ASN A C 1 ATOM 2423 O O . ASN A 1 309 ? -39.339 50.063 -20.552 1.00 32.49 ? 310 ASN A O 1 ATOM 2424 C CB . ASN A 1 309 ? -40.219 51.143 -23.405 1.00 44.31 ? 310 ASN A CB 1 ATOM 2425 C CG . ASN A 1 309 ? -39.375 51.025 -24.646 1.00 50.37 ? 310 ASN A CG 1 ATOM 2426 O OD1 . ASN A 1 309 ? -38.481 50.171 -24.719 1.00 53.79 ? 310 ASN A OD1 1 ATOM 2427 N ND2 . ASN A 1 309 ? -39.662 51.834 -25.633 1.00 54.02 ? 310 ASN A ND2 1 ATOM 2428 N N . SER A 1 310 ? -41.549 50.346 -20.641 1.00 32.88 ? 311 SER A N 1 ATOM 2429 C CA . SER A 1 310 ? -41.703 50.714 -19.251 1.00 34.00 ? 311 SER A CA 1 ATOM 2430 C C . SER A 1 310 ? -41.865 49.468 -18.378 1.00 35.87 ? 311 SER A C 1 ATOM 2431 O O . SER A 1 310 ? -41.924 49.592 -17.189 1.00 37.12 ? 311 SER A O 1 ATOM 2432 C CB . SER A 1 310 ? -42.945 51.605 -19.093 1.00 35.03 ? 311 SER A CB 1 ATOM 2433 O OG . SER A 1 310 ? -44.101 50.849 -19.442 1.00 44.46 ? 311 SER A OG 1 ATOM 2434 N N . GLY A 1 311 ? -41.943 48.276 -18.960 1.00 34.95 ? 312 GLY A N 1 ATOM 2435 C CA . GLY A 1 311 ? -42.146 47.054 -18.178 1.00 31.82 ? 312 GLY A CA 1 ATOM 2436 C C . GLY A 1 311 ? -43.609 46.912 -17.727 1.00 34.14 ? 312 GLY A C 1 ATOM 2437 O O . GLY A 1 311 ? -43.932 46.223 -16.784 1.00 27.12 ? 312 GLY A O 1 ATOM 2438 N N . ASN A 1 312 ? -44.516 47.590 -18.393 1.00 30.99 ? 313 ASN A N 1 ATOM 2439 C CA . ASN A 1 312 ? -45.888 47.434 -18.086 1.00 28.52 ? 313 ASN A CA 1 ATOM 2440 C C . ASN A 1 312 ? -46.429 46.138 -18.706 1.00 30.49 ? 313 ASN A C 1 ATOM 2441 O O . ASN A 1 312 ? -47.063 46.145 -19.780 1.00 32.78 ? 313 ASN A O 1 ATOM 2442 C CB . ASN A 1 312 ? -46.693 48.673 -18.527 1.00 26.15 ? 313 ASN A CB 1 ATOM 2443 C CG . ASN A 1 312 ? -48.076 48.662 -17.945 1.00 30.37 ? 313 ASN A CG 1 ATOM 2444 O OD1 . ASN A 1 312 ? -48.381 47.778 -17.134 1.00 35.37 ? 313 ASN A OD1 1 ATOM 2445 N ND2 . ASN A 1 312 ? -48.950 49.573 -18.398 1.00 32.16 ? 313 ASN A ND2 1 ATOM 2446 N N . PHE A 1 313 ? -46.169 45.034 -18.011 1.00 29.68 ? 314 PHE A N 1 ATOM 2447 C CA . PHE A 1 313 ? -46.610 43.712 -18.417 1.00 30.78 ? 314 PHE A CA 1 ATOM 2448 C C . PHE A 1 313 ? -46.381 42.665 -17.332 1.00 31.01 ? 314 PHE A C 1 ATOM 2449 O O . PHE A 1 313 ? -45.654 42.909 -16.402 1.00 30.59 ? 314 PHE A O 1 ATOM 2450 C CB . PHE A 1 313 ? -45.921 43.265 -19.732 1.00 28.42 ? 314 PHE A CB 1 ATOM 2451 C CG . PHE A 1 313 ? -44.430 43.430 -19.758 1.00 26.12 ? 314 PHE A CG 1 ATOM 2452 C CD1 . PHE A 1 313 ? -43.579 42.448 -19.239 1.00 25.46 ? 314 PHE A CD1 1 ATOM 2453 C CD2 . PHE A 1 313 ? -43.862 44.523 -20.387 1.00 27.84 ? 314 PHE A CD2 1 ATOM 2454 C CE1 . PHE A 1 313 ? -42.185 42.605 -19.280 1.00 22.65 ? 314 PHE A CE1 1 ATOM 2455 C CE2 . PHE A 1 313 ? -42.448 44.640 -20.481 1.00 26.53 ? 314 PHE A CE2 1 ATOM 2456 C CZ . PHE A 1 313 ? -41.627 43.692 -19.914 1.00 24.07 ? 314 PHE A CZ 1 ATOM 2457 N N . LYS A 1 314 ? -46.970 41.481 -17.512 1.00 30.78 ? 315 LYS A N 1 ATOM 2458 C CA . LYS A 1 314 ? -46.817 40.407 -16.553 1.00 29.80 ? 315 LYS A CA 1 ATOM 2459 C C . LYS A 1 314 ? -45.397 39.930 -16.539 1.00 32.31 ? 315 LYS A C 1 ATOM 2460 O O . LYS A 1 314 ? -44.832 39.580 -17.595 1.00 29.93 ? 315 LYS A O 1 ATOM 2461 C CB . LYS A 1 314 ? -47.727 39.218 -16.918 1.00 29.69 ? 315 LYS A CB 1 ATOM 2462 C CG . LYS A 1 314 ? -47.916 38.186 -15.810 1.00 26.01 ? 315 LYS A CG 1 ATOM 2463 C CD . LYS A 1 314 ? -48.570 36.910 -16.284 1.00 29.96 ? 315 LYS A CD 1 ATOM 2464 C CE . LYS A 1 314 ? -48.610 35.926 -15.142 1.00 32.73 ? 315 LYS A CE 1 ATOM 2465 N NZ . LYS A 1 314 ? -49.743 36.219 -14.237 1.00 26.73 ? 315 LYS A NZ 1 ATOM 2466 N N . LYS A 1 315 ? -44.831 39.855 -15.342 1.00 30.66 ? 316 LYS A N 1 ATOM 2467 C CA . LYS A 1 315 ? -43.482 39.312 -15.190 1.00 30.97 ? 316 LYS A CA 1 ATOM 2468 C C . LYS A 1 315 ? -43.494 37.866 -14.771 1.00 32.41 ? 316 LYS A C 1 ATOM 2469 O O . LYS A 1 315 ? -43.895 37.566 -13.729 1.00 33.69 ? 316 LYS A O 1 ATOM 2470 C CB . LYS A 1 315 ? -42.728 40.163 -14.185 1.00 35.59 ? 316 LYS A CB 1 ATOM 2471 C CG . LYS A 1 315 ? -42.482 41.501 -14.860 1.00 41.08 ? 316 LYS A CG 1 ATOM 2472 C CD . LYS A 1 315 ? -42.285 42.666 -13.957 1.00 39.82 ? 316 LYS A CD 1 ATOM 2473 C CE . LYS A 1 315 ? -42.297 43.904 -14.821 1.00 42.64 ? 316 LYS A CE 1 ATOM 2474 N NZ . LYS A 1 315 ? -43.347 44.830 -14.385 1.00 47.02 ? 316 LYS A NZ 1 ATOM 2475 N N . THR A 1 316 ? -43.001 36.962 -15.601 1.00 33.15 ? 317 THR A N 1 ATOM 2476 C CA . THR A 1 316 ? -43.104 35.566 -15.322 1.00 30.27 ? 317 THR A CA 1 ATOM 2477 C C . THR A 1 316 ? -42.096 34.918 -16.214 1.00 30.47 ? 317 THR A C 1 ATOM 2478 O O . THR A 1 316 ? -41.135 35.593 -16.654 1.00 31.57 ? 317 THR A O 1 ATOM 2479 C CB . THR A 1 316 ? -44.529 35.081 -15.556 1.00 33.33 ? 317 THR A CB 1 ATOM 2480 O OG1 . THR A 1 316 ? -44.588 33.704 -15.226 1.00 32.90 ? 317 THR A OG1 1 ATOM 2481 C CG2 . THR A 1 316 ? -44.994 35.359 -17.064 1.00 33.49 ? 317 THR A CG2 1 ATOM 2482 N N . GLN A 1 317 ? -42.258 33.635 -16.480 1.00 28.65 ? 318 GLN A N 1 ATOM 2483 C CA . GLN A 1 317 ? -41.341 32.969 -17.398 1.00 30.02 ? 318 GLN A CA 1 ATOM 2484 C C . GLN A 1 317 ? -41.998 32.835 -18.755 1.00 29.25 ? 318 GLN A C 1 ATOM 2485 O O . GLN A 1 317 ? -43.219 32.746 -18.864 1.00 28.89 ? 318 GLN A O 1 ATOM 2486 C CB . GLN A 1 317 ? -40.933 31.568 -16.922 1.00 31.37 ? 318 GLN A CB 1 ATOM 2487 C CG . GLN A 1 317 ? -40.295 31.486 -15.523 1.00 35.41 ? 318 GLN A CG 1 ATOM 2488 C CD . GLN A 1 317 ? -41.337 31.497 -14.381 1.00 33.51 ? 318 GLN A CD 1 ATOM 2489 O OE1 . GLN A 1 317 ? -42.470 31.016 -14.524 1.00 30.35 ? 318 GLN A OE1 1 ATOM 2490 N NE2 . GLN A 1 317 ? -41.001 32.186 -13.307 1.00 35.24 ? 318 GLN A NE2 1 ATOM 2491 N N . ILE A 1 318 ? -41.185 32.766 -19.789 1.00 27.83 ? 319 ILE A N 1 ATOM 2492 C CA . ILE A 1 318 ? -41.738 32.559 -21.133 1.00 26.30 ? 319 ILE A CA 1 ATOM 2493 C C . ILE A 1 318 ? -40.782 31.708 -21.900 1.00 25.94 ? 319 ILE A C 1 ATOM 2494 O O . ILE A 1 318 ? -39.561 31.734 -21.664 1.00 23.19 ? 319 ILE A O 1 ATOM 2495 C CB . ILE A 1 318 ? -41.965 33.880 -21.927 1.00 25.62 ? 319 ILE A CB 1 ATOM 2496 C CG1 . ILE A 1 318 ? -40.673 34.627 -22.146 1.00 25.35 ? 319 ILE A CG1 1 ATOM 2497 C CG2 . ILE A 1 318 ? -42.913 34.825 -21.227 1.00 26.27 ? 319 ILE A CG2 1 ATOM 2498 C CD1 . ILE A 1 318 ? -40.813 35.789 -23.095 1.00 25.98 ? 319 ILE A CD1 1 ATOM 2499 N N . LEU A 1 319 ? -41.381 30.953 -22.813 1.00 25.36 ? 320 LEU A N 1 ATOM 2500 C CA . LEU A 1 319 ? -40.699 30.111 -23.725 1.00 28.60 ? 320 LEU A CA 1 ATOM 2501 C C . LEU A 1 319 ? -41.331 30.362 -25.103 1.00 31.33 ? 320 LEU A C 1 ATOM 2502 O O . LEU A 1 319 ? -42.564 30.360 -25.275 1.00 28.42 ? 320 LEU A O 1 ATOM 2503 C CB . LEU A 1 319 ? -40.871 28.671 -23.311 1.00 29.19 ? 320 LEU A CB 1 ATOM 2504 C CG . LEU A 1 319 ? -40.167 27.579 -24.145 1.00 32.45 ? 320 LEU A CG 1 ATOM 2505 C CD1 . LEU A 1 319 ? -40.101 26.299 -23.327 1.00 33.01 ? 320 LEU A CD1 1 ATOM 2506 C CD2 . LEU A 1 319 ? -40.907 27.270 -25.433 1.00 32.05 ? 320 LEU A CD2 1 ATOM 2507 N N . LEU A 1 320 ? -40.457 30.570 -26.073 1.00 32.45 ? 321 LEU A N 1 ATOM 2508 C CA . LEU A 1 320 ? -40.854 31.118 -27.335 1.00 29.93 ? 321 LEU A CA 1 ATOM 2509 C C . LEU A 1 320 ? -39.776 30.907 -28.408 1.00 31.70 ? 321 LEU A C 1 ATOM 2510 O O . LEU A 1 320 ? -38.619 30.577 -28.154 1.00 27.44 ? 321 LEU A O 1 ATOM 2511 C CB . LEU A 1 320 ? -41.297 32.567 -27.211 1.00 26.84 ? 321 LEU A CB 1 ATOM 2512 C CG . LEU A 1 320 ? -40.228 33.665 -27.218 1.00 27.67 ? 321 LEU A CG 1 ATOM 2513 C CD1 . LEU A 1 320 ? -40.917 34.992 -27.147 1.00 23.68 ? 321 LEU A CD1 1 ATOM 2514 C CD2 . LEU A 1 320 ? -39.264 33.551 -26.103 1.00 28.66 ? 321 LEU A CD2 1 ATOM 2515 N N . GLY A 1 321 ? -40.240 30.981 -29.641 1.00 30.31 ? 322 GLY A N 1 ATOM 2516 C CA . GLY A 1 321 ? -39.353 30.798 -30.758 1.00 31.17 ? 322 GLY A CA 1 ATOM 2517 C C . GLY A 1 321 ? -40.019 30.892 -32.095 1.00 27.30 ? 322 GLY A C 1 ATOM 2518 O O . GLY A 1 321 ? -41.222 31.224 -32.212 1.00 22.64 ? 322 GLY A O 1 ATOM 2519 N N . VAL A 1 322 ? -39.200 30.564 -33.093 1.00 27.61 ? 323 VAL A N 1 ATOM 2520 C CA . VAL A 1 322 ? -39.577 30.643 -34.486 1.00 26.91 ? 323 VAL A CA 1 ATOM 2521 C C . VAL A 1 322 ? -39.173 29.425 -35.350 1.00 28.83 ? 323 VAL A C 1 ATOM 2522 O O . VAL A 1 322 ? -38.396 28.604 -34.937 1.00 29.44 ? 323 VAL A O 1 ATOM 2523 C CB . VAL A 1 322 ? -39.031 31.887 -35.094 1.00 25.31 ? 323 VAL A CB 1 ATOM 2524 C CG1 . VAL A 1 322 ? -39.494 33.089 -34.327 1.00 27.37 ? 323 VAL A CG1 1 ATOM 2525 C CG2 . VAL A 1 322 ? -37.531 31.837 -35.155 1.00 28.28 ? 323 VAL A CG2 1 ATOM 2526 N N . ASN A 1 323 ? -39.827 29.286 -36.508 1.00 28.53 ? 324 ASN A N 1 ATOM 2527 C CA . ASN A 1 323 ? -39.406 28.347 -37.556 1.00 27.08 ? 324 ASN A CA 1 ATOM 2528 C C . ASN A 1 323 ? -38.527 28.997 -38.600 1.00 24.55 ? 324 ASN A C 1 ATOM 2529 O O . ASN A 1 323 ? -38.566 30.181 -38.809 1.00 25.02 ? 324 ASN A O 1 ATOM 2530 C CB . ASN A 1 323 ? -40.638 27.730 -38.209 1.00 27.71 ? 324 ASN A CB 1 ATOM 2531 C CG . ASN A 1 323 ? -41.499 26.975 -37.217 1.00 28.62 ? 324 ASN A CG 1 ATOM 2532 O OD1 . ASN A 1 323 ? -41.187 26.937 -36.041 1.00 28.82 ? 324 ASN A OD1 1 ATOM 2533 N ND2 . ASN A 1 323 ? -42.583 26.348 -37.699 1.00 31.34 ? 324 ASN A ND2 1 ATOM 2534 N N . LYS A 1 324 ? -37.727 28.206 -39.274 1.00 26.97 ? 325 LYS A N 1 ATOM 2535 C CA . LYS A 1 324 ? -36.766 28.718 -40.201 1.00 26.99 ? 325 LYS A CA 1 ATOM 2536 C C . LYS A 1 324 ? -37.338 29.443 -41.404 1.00 28.94 ? 325 LYS A C 1 ATOM 2537 O O . LYS A 1 324 ? -36.739 30.418 -41.866 1.00 24.56 ? 325 LYS A O 1 ATOM 2538 C CB . LYS A 1 324 ? -35.939 27.582 -40.712 1.00 32.63 ? 325 LYS A CB 1 ATOM 2539 C CG . LYS A 1 324 ? -34.706 27.985 -41.532 1.00 33.38 ? 325 LYS A CG 1 ATOM 2540 C CD . LYS A 1 324 ? -34.152 26.666 -42.087 1.00 39.12 ? 325 LYS A CD 1 ATOM 2541 C CE . LYS A 1 324 ? -32.830 26.830 -42.816 1.00 46.55 ? 325 LYS A CE 1 ATOM 2542 N NZ . LYS A 1 324 ? -32.995 27.783 -43.936 1.00 53.85 ? 325 LYS A NZ 1 ATOM 2543 N N . ASP A 1 325 ? -38.506 29.009 -41.886 1.00 26.30 ? 326 ASP A N 1 ATOM 2544 C CA . ASP A 1 325 ? -39.069 29.567 -43.112 1.00 25.94 ? 326 ASP A CA 1 ATOM 2545 C C . ASP A 1 325 ? -40.522 30.000 -42.900 1.00 31.37 ? 326 ASP A C 1 ATOM 2546 O O . ASP A 1 325 ? -41.510 29.433 -43.517 1.00 32.04 ? 326 ASP A O 1 ATOM 2547 C CB . ASP A 1 325 ? -38.970 28.505 -44.244 1.00 24.12 ? 326 ASP A CB 1 ATOM 2548 C CG . ASP A 1 325 ? -37.531 28.040 -44.501 1.00 26.68 ? 326 ASP A CG 1 ATOM 2549 O OD1 . ASP A 1 325 ? -36.695 28.864 -44.882 1.00 27.09 ? 326 ASP A OD1 1 ATOM 2550 O OD2 . ASP A 1 325 ? -37.214 26.846 -44.260 1.00 28.55 ? 326 ASP A OD2 1 ATOM 2551 N N . GLU A 1 326 ? -40.657 30.987 -42.024 1.00 30.60 ? 327 GLU A N 1 ATOM 2552 C CA . GLU A 1 326 ? -41.924 31.569 -41.679 1.00 30.03 ? 327 GLU A CA 1 ATOM 2553 C C . GLU A 1 326 ? -42.626 32.199 -42.900 1.00 32.02 ? 327 GLU A C 1 ATOM 2554 O O . GLU A 1 326 ? -43.840 32.104 -42.992 1.00 34.17 ? 327 GLU A O 1 ATOM 2555 C CB . GLU A 1 326 ? -41.751 32.648 -40.576 1.00 31.80 ? 327 GLU A CB 1 ATOM 2556 C CG . GLU A 1 326 ? -41.296 32.181 -39.200 1.00 31.00 ? 327 GLU A CG 1 ATOM 2557 C CD . GLU A 1 326 ? -42.299 31.371 -38.406 1.00 29.75 ? 327 GLU A CD 1 ATOM 2558 O OE1 . GLU A 1 326 ? -43.433 31.080 -38.851 1.00 32.06 ? 327 GLU A OE1 1 ATOM 2559 O OE2 . GLU A 1 326 ? -41.951 30.995 -37.271 1.00 33.21 ? 327 GLU A OE2 1 ATOM 2560 N N . GLY A 1 327 ? -41.883 32.781 -43.864 1.00 30.30 ? 328 GLY A N 1 ATOM 2561 C CA . GLY A 1 327 ? -42.553 33.478 -44.980 1.00 30.40 ? 328 GLY A CA 1 ATOM 2562 C C . GLY A 1 327 ? -43.175 32.732 -46.159 1.00 28.10 ? 328 GLY A C 1 ATOM 2563 O O . GLY A 1 327 ? -43.947 33.308 -46.937 1.00 27.77 ? 328 GLY A O 1 ATOM 2564 N N . SER A 1 328 ? -42.908 31.448 -46.294 1.00 30.56 ? 329 SER A N 1 ATOM 2565 C CA . SER A 1 328 ? -43.117 30.792 -47.581 1.00 26.71 ? 329 SER A CA 1 ATOM 2566 C C . SER A 1 328 ? -44.562 30.694 -47.946 1.00 30.07 ? 329 SER A C 1 ATOM 2567 O O . SER A 1 328 ? -44.939 30.830 -49.152 1.00 30.62 ? 329 SER A O 1 ATOM 2568 C CB . SER A 1 328 ? -42.406 29.473 -47.632 1.00 25.04 ? 329 SER A CB 1 ATOM 2569 O OG . SER A 1 328 ? -42.858 28.598 -46.660 1.00 26.82 ? 329 SER A OG 1 ATOM 2570 N N . PHE A 1 329 ? -45.388 30.406 -46.953 1.00 29.75 ? 330 PHE A N 1 ATOM 2571 C CA . PHE A 1 329 ? -46.823 30.284 -47.158 1.00 31.43 ? 330 PHE A CA 1 ATOM 2572 C C . PHE A 1 329 ? -47.408 31.546 -47.800 1.00 30.46 ? 330 PHE A C 1 ATOM 2573 O O . PHE A 1 329 ? -48.292 31.492 -48.658 1.00 30.78 ? 330 PHE A O 1 ATOM 2574 C CB . PHE A 1 329 ? -47.503 30.140 -45.804 1.00 36.07 ? 330 PHE A CB 1 ATOM 2575 C CG . PHE A 1 329 ? -48.304 28.969 -45.687 1.00 40.21 ? 330 PHE A CG 1 ATOM 2576 C CD1 . PHE A 1 329 ? -49.473 28.876 -46.383 1.00 47.72 ? 330 PHE A CD1 1 ATOM 2577 C CD2 . PHE A 1 329 ? -47.910 27.946 -44.851 1.00 52.81 ? 330 PHE A CD2 1 ATOM 2578 C CE1 . PHE A 1 329 ? -50.254 27.733 -46.300 1.00 55.84 ? 330 PHE A CE1 1 ATOM 2579 C CE2 . PHE A 1 329 ? -48.667 26.788 -44.745 1.00 58.82 ? 330 PHE A CE2 1 ATOM 2580 C CZ . PHE A 1 329 ? -49.843 26.670 -45.490 1.00 60.01 ? 330 PHE A CZ 1 ATOM 2581 N N . PHE A 1 330 ? -46.951 32.696 -47.330 1.00 27.17 ? 331 PHE A N 1 ATOM 2582 C CA . PHE A 1 330 ? -47.600 33.929 -47.684 1.00 27.05 ? 331 PHE A CA 1 ATOM 2583 C C . PHE A 1 330 ? -47.143 34.302 -49.070 1.00 27.30 ? 331 PHE A C 1 ATOM 2584 O O . PHE A 1 330 ? -47.878 34.918 -49.774 1.00 30.82 ? 331 PHE A O 1 ATOM 2585 C CB . PHE A 1 330 ? -47.305 35.017 -46.644 1.00 28.66 ? 331 PHE A CB 1 ATOM 2586 C CG . PHE A 1 330 ? -47.768 34.630 -45.274 1.00 28.50 ? 331 PHE A CG 1 ATOM 2587 C CD1 . PHE A 1 330 ? -46.957 33.839 -44.465 1.00 28.81 ? 331 PHE A CD1 1 ATOM 2588 C CD2 . PHE A 1 330 ? -49.074 34.849 -44.912 1.00 29.41 ? 331 PHE A CD2 1 ATOM 2589 C CE1 . PHE A 1 330 ? -47.420 33.365 -43.273 1.00 30.55 ? 331 PHE A CE1 1 ATOM 2590 C CE2 . PHE A 1 330 ? -49.533 34.400 -43.709 1.00 30.37 ? 331 PHE A CE2 1 ATOM 2591 C CZ . PHE A 1 330 ? -48.704 33.664 -42.888 1.00 29.62 ? 331 PHE A CZ 1 ATOM 2592 N N . LEU A 1 331 ? -45.923 33.935 -49.445 1.00 25.46 ? 332 LEU A N 1 ATOM 2593 C CA . LEU A 1 331 ? -45.427 34.103 -50.790 1.00 27.09 ? 332 LEU A CA 1 ATOM 2594 C C . LEU A 1 331 ? -46.154 33.202 -51.818 1.00 28.23 ? 332 LEU A C 1 ATOM 2595 O O . LEU A 1 331 ? -46.653 33.687 -52.874 1.00 27.18 ? 332 LEU A O 1 ATOM 2596 C CB . LEU A 1 331 ? -43.937 33.867 -50.830 1.00 27.17 ? 332 LEU A CB 1 ATOM 2597 C CG . LEU A 1 331 ? -43.139 34.963 -50.163 1.00 25.91 ? 332 LEU A CG 1 ATOM 2598 C CD1 . LEU A 1 331 ? -41.741 34.530 -49.903 1.00 26.50 ? 332 LEU A CD1 1 ATOM 2599 C CD2 . LEU A 1 331 ? -43.127 36.164 -51.048 1.00 28.67 ? 332 LEU A CD2 1 ATOM 2600 N N . LEU A 1 332 ? -46.287 31.944 -51.455 1.00 25.65 ? 333 LEU A N 1 ATOM 2601 C CA . LEU A 1 332 ? -47.056 30.985 -52.244 1.00 28.31 ? 333 LEU A CA 1 ATOM 2602 C C . LEU A 1 332 ? -48.418 31.520 -52.556 1.00 31.48 ? 333 LEU A C 1 ATOM 2603 O O . LEU A 1 332 ? -48.813 31.580 -53.725 1.00 30.44 ? 333 LEU A O 1 ATOM 2604 C CB . LEU A 1 332 ? -47.217 29.678 -51.494 1.00 26.25 ? 333 LEU A CB 1 ATOM 2605 C CG . LEU A 1 332 ? -48.150 28.700 -52.166 1.00 30.62 ? 333 LEU A CG 1 ATOM 2606 C CD1 . LEU A 1 332 ? -47.601 28.321 -53.573 1.00 31.13 ? 333 LEU A CD1 1 ATOM 2607 C CD2 . LEU A 1 332 ? -48.285 27.450 -51.299 1.00 28.44 ? 333 LEU A CD2 1 ATOM 2608 N N . TYR A 1 333 ? -49.129 31.949 -51.514 1.00 30.91 ? 334 TYR A N 1 ATOM 2609 C CA . TYR A 1 333 ? -50.481 32.401 -51.722 1.00 29.51 ? 334 TYR A CA 1 ATOM 2610 C C . TYR A 1 333 ? -50.586 33.763 -52.370 1.00 29.44 ? 334 TYR A C 1 ATOM 2611 O O . TYR A 1 333 ? -51.514 34.007 -53.110 1.00 31.40 ? 334 TYR A O 1 ATOM 2612 C CB . TYR A 1 333 ? -51.297 32.408 -50.453 1.00 29.45 ? 334 TYR A CB 1 ATOM 2613 C CG . TYR A 1 333 ? -51.857 31.065 -50.122 1.00 28.50 ? 334 TYR A CG 1 ATOM 2614 C CD1 . TYR A 1 333 ? -51.005 30.008 -49.830 1.00 30.01 ? 334 TYR A CD1 1 ATOM 2615 C CD2 . TYR A 1 333 ? -53.232 30.838 -50.082 1.00 27.44 ? 334 TYR A CD2 1 ATOM 2616 C CE1 . TYR A 1 333 ? -51.474 28.746 -49.547 1.00 26.67 ? 334 TYR A CE1 1 ATOM 2617 C CE2 . TYR A 1 333 ? -53.728 29.562 -49.797 1.00 26.80 ? 334 TYR A CE2 1 ATOM 2618 C CZ . TYR A 1 333 ? -52.838 28.513 -49.539 1.00 27.71 ? 334 TYR A CZ 1 ATOM 2619 O OH . TYR A 1 333 ? -53.277 27.230 -49.221 1.00 26.59 ? 334 TYR A OH 1 ATOM 2620 N N . GLY A 1 334 ? -49.654 34.651 -52.133 1.00 28.41 ? 335 GLY A N 1 ATOM 2621 C CA . GLY A 1 334 ? -49.892 36.026 -52.543 1.00 27.55 ? 335 GLY A CA 1 ATOM 2622 C C . GLY A 1 334 ? -48.888 36.720 -53.457 1.00 30.65 ? 335 GLY A C 1 ATOM 2623 O O . GLY A 1 334 ? -49.095 37.850 -53.764 1.00 33.25 ? 335 GLY A O 1 ATOM 2624 N N . ALA A 1 335 ? -47.732 36.125 -53.732 1.00 27.12 ? 336 ALA A N 1 ATOM 2625 C CA . ALA A 1 335 ? -46.748 36.821 -54.441 1.00 29.32 ? 336 ALA A CA 1 ATOM 2626 C C . ALA A 1 335 ? -46.544 36.169 -55.839 1.00 30.73 ? 336 ALA A C 1 ATOM 2627 O O . ALA A 1 335 ? -46.581 34.928 -55.992 1.00 27.57 ? 336 ALA A O 1 ATOM 2628 C CB . ALA A 1 335 ? -45.434 36.845 -53.663 1.00 30.94 ? 336 ALA A CB 1 ATOM 2629 N N . PRO A 1 336 ? -46.360 37.014 -56.850 1.00 36.32 ? 337 PRO A N 1 ATOM 2630 C CA . PRO A 1 336 ? -46.199 36.503 -58.217 1.00 38.75 ? 337 PRO A CA 1 ATOM 2631 C C . PRO A 1 336 ? -44.920 35.696 -58.409 1.00 31.36 ? 337 PRO A C 1 ATOM 2632 O O . PRO A 1 336 ? -43.858 36.118 -57.985 1.00 30.48 ? 337 PRO A O 1 ATOM 2633 C CB . PRO A 1 336 ? -46.189 37.779 -59.066 1.00 40.34 ? 337 PRO A CB 1 ATOM 2634 C CG . PRO A 1 336 ? -45.618 38.838 -58.121 1.00 44.79 ? 337 PRO A CG 1 ATOM 2635 C CD . PRO A 1 336 ? -46.127 38.481 -56.765 1.00 39.81 ? 337 PRO A CD 1 ATOM 2636 N N . GLY A 1 337 ? -45.037 34.541 -59.078 1.00 33.25 ? 338 GLY A N 1 ATOM 2637 C CA . GLY A 1 337 ? -43.841 33.735 -59.473 1.00 30.60 ? 338 GLY A CA 1 ATOM 2638 C C . GLY A 1 337 ? -43.650 32.470 -58.587 1.00 32.08 ? 338 GLY A C 1 ATOM 2639 O O . GLY A 1 337 ? -42.793 31.610 -58.882 1.00 31.06 ? 338 GLY A O 1 ATOM 2640 N N . PHE A 1 338 ? -44.474 32.352 -57.540 1.00 26.17 ? 339 PHE A N 1 ATOM 2641 C CA . PHE A 1 338 ? -44.397 31.241 -56.590 1.00 27.51 ? 339 PHE A CA 1 ATOM 2642 C C . PHE A 1 338 ? -45.610 30.444 -56.850 1.00 26.61 ? 339 PHE A C 1 ATOM 2643 O O . PHE A 1 338 ? -46.706 31.011 -56.948 1.00 33.59 ? 339 PHE A O 1 ATOM 2644 C CB . PHE A 1 338 ? -44.498 31.713 -55.114 1.00 24.22 ? 339 PHE A CB 1 ATOM 2645 C CG . PHE A 1 338 ? -43.392 32.582 -54.684 1.00 22.07 ? 339 PHE A CG 1 ATOM 2646 C CD1 . PHE A 1 338 ? -43.440 33.939 -54.903 1.00 24.88 ? 339 PHE A CD1 1 ATOM 2647 C CD2 . PHE A 1 338 ? -42.286 32.061 -54.014 1.00 27.68 ? 339 PHE A CD2 1 ATOM 2648 C CE1 . PHE A 1 338 ? -42.404 34.771 -54.482 1.00 24.28 ? 339 PHE A CE1 1 ATOM 2649 C CE2 . PHE A 1 338 ? -41.241 32.903 -53.561 1.00 23.82 ? 339 PHE A CE2 1 ATOM 2650 C CZ . PHE A 1 338 ? -41.309 34.234 -53.819 1.00 23.59 ? 339 PHE A CZ 1 ATOM 2651 N N . SER A 1 339 ? -45.424 29.144 -56.911 1.00 27.32 ? 340 SER A N 1 ATOM 2652 C CA . SER A 1 339 ? -46.495 28.201 -57.164 1.00 28.89 ? 340 SER A CA 1 ATOM 2653 C C . SER A 1 339 ? -46.198 26.949 -56.372 1.00 27.00 ? 340 SER A C 1 ATOM 2654 O O . SER A 1 339 ? -45.036 26.640 -56.062 1.00 26.90 ? 340 SER A O 1 ATOM 2655 C CB . SER A 1 339 ? -46.508 27.792 -58.638 1.00 34.38 ? 340 SER A CB 1 ATOM 2656 O OG . SER A 1 339 ? -46.158 28.856 -59.501 1.00 45.01 ? 340 SER A OG 1 ATOM 2657 N N . LYS A 1 340 ? -47.249 26.199 -56.120 1.00 26.91 ? 341 LYS A N 1 ATOM 2658 C CA . LYS A 1 340 ? -47.130 25.029 -55.368 1.00 29.93 ? 341 LYS A CA 1 ATOM 2659 C C . LYS A 1 340 ? -46.334 23.903 -56.005 1.00 32.59 ? 341 LYS A C 1 ATOM 2660 O O . LYS A 1 340 ? -45.641 23.099 -55.275 1.00 30.81 ? 341 LYS A O 1 ATOM 2661 C CB . LYS A 1 340 ? -48.503 24.498 -55.037 1.00 29.92 ? 341 LYS A CB 1 ATOM 2662 C CG . LYS A 1 340 ? -48.421 23.446 -53.923 1.00 31.25 ? 341 LYS A CG 1 ATOM 2663 C CD . LYS A 1 340 ? -49.785 23.107 -53.361 1.00 31.79 ? 341 LYS A CD 1 ATOM 2664 C CE . LYS A 1 340 ? -50.527 22.108 -54.208 1.00 35.39 ? 341 LYS A CE 1 ATOM 2665 N NZ . LYS A 1 340 ? -49.723 20.929 -54.681 1.00 36.17 ? 341 LYS A NZ 1 ATOM 2666 N N . ASP A 1 341 ? -46.499 23.754 -57.318 1.00 28.45 ? 342 ASP A N 1 ATOM 2667 C CA . ASP A 1 341 ? -45.905 22.602 -58.007 1.00 27.97 ? 342 ASP A CA 1 ATOM 2668 C C . ASP A 1 341 ? -44.677 22.965 -58.842 1.00 28.56 ? 342 ASP A C 1 ATOM 2669 O O . ASP A 1 341 ? -44.262 22.176 -59.633 1.00 31.07 ? 342 ASP A O 1 ATOM 2670 C CB . ASP A 1 341 ? -46.929 21.896 -58.859 1.00 30.15 ? 342 ASP A CB 1 ATOM 2671 C CG . ASP A 1 341 ? -48.174 21.511 -58.102 1.00 32.10 ? 342 ASP A CG 1 ATOM 2672 O OD1 . ASP A 1 341 ? -48.127 21.417 -56.847 1.00 36.02 ? 342 ASP A OD1 1 ATOM 2673 O OD2 . ASP A 1 341 ? -49.235 21.348 -58.769 1.00 34.24 ? 342 ASP A OD2 1 ATOM 2674 N N . SER A 1 342 ? -44.066 24.142 -58.671 1.00 29.38 ? 343 SER A N 1 ATOM 2675 C CA . SER A 1 342 ? -42.696 24.361 -59.174 1.00 28.89 ? 343 SER A CA 1 ATOM 2676 C C . SER A 1 342 ? -41.801 24.712 -58.044 1.00 31.90 ? 343 SER A C 1 ATOM 2677 O O . SER A 1 342 ? -42.269 25.012 -56.968 1.00 33.60 ? 343 SER A O 1 ATOM 2678 C CB . SER A 1 342 ? -42.605 25.522 -60.158 1.00 29.41 ? 343 SER A CB 1 ATOM 2679 O OG . SER A 1 342 ? -43.154 26.700 -59.678 1.00 38.87 ? 343 SER A OG 1 ATOM 2680 N N . GLU A 1 343 ? -40.517 24.739 -58.360 1.00 33.53 ? 344 GLU A N 1 ATOM 2681 C CA . GLU A 1 343 ? -39.445 25.175 -57.522 1.00 36.13 ? 344 GLU A CA 1 ATOM 2682 C C . GLU A 1 343 ? -39.515 26.689 -57.228 1.00 31.68 ? 344 GLU A C 1 ATOM 2683 O O . GLU A 1 343 ? -38.776 27.194 -56.378 1.00 28.35 ? 344 GLU A O 1 ATOM 2684 C CB . GLU A 1 343 ? -38.100 24.915 -58.247 1.00 40.90 ? 344 GLU A CB 1 ATOM 2685 C CG . GLU A 1 343 ? -37.605 23.465 -58.216 1.00 57.23 ? 344 GLU A CG 1 ATOM 2686 C CD . GLU A 1 343 ? -36.103 23.328 -58.570 1.00 63.73 ? 344 GLU A CD 1 ATOM 2687 O OE1 . GLU A 1 343 ? -35.522 24.148 -59.314 1.00 64.54 ? 344 GLU A OE1 1 ATOM 2688 O OE2 . GLU A 1 343 ? -35.481 22.383 -58.073 1.00 84.14 ? 344 GLU A OE2 1 ATOM 2689 N N . SER A 1 344 ? -40.296 27.420 -58.003 1.00 26.86 ? 345 SER A N 1 ATOM 2690 C CA . SER A 1 344 ? -40.524 28.818 -57.749 1.00 29.70 ? 345 SER A CA 1 ATOM 2691 C C . SER A 1 344 ? -39.263 29.615 -57.767 1.00 31.23 ? 345 SER A C 1 ATOM 2692 O O . SER A 1 344 ? -39.014 30.467 -56.905 1.00 33.62 ? 345 SER A O 1 ATOM 2693 C CB . SER A 1 344 ? -41.290 29.031 -56.444 1.00 28.44 ? 345 SER A CB 1 ATOM 2694 O OG . SER A 1 344 ? -42.550 28.406 -56.596 1.00 37.07 ? 345 SER A OG 1 ATOM 2695 N N . LYS A 1 345 ? -38.481 29.406 -58.795 1.00 32.91 ? 346 LYS A N 1 ATOM 2696 C CA . LYS A 1 345 ? -37.336 30.282 -59.003 1.00 37.24 ? 346 LYS A CA 1 ATOM 2697 C C . LYS A 1 345 ? -37.817 31.633 -59.478 1.00 35.29 ? 346 LYS A C 1 ATOM 2698 O O . LYS A 1 345 ? -38.688 31.743 -60.296 1.00 43.72 ? 346 LYS A O 1 ATOM 2699 C CB . LYS A 1 345 ? -36.378 29.653 -59.965 1.00 41.34 ? 346 LYS A CB 1 ATOM 2700 C CG . LYS A 1 345 ? -35.734 28.367 -59.451 1.00 45.60 ? 346 LYS A CG 1 ATOM 2701 C CD . LYS A 1 345 ? -34.706 27.916 -60.494 1.00 59.76 ? 346 LYS A CD 1 ATOM 2702 C CE . LYS A 1 345 ? -34.606 26.397 -60.637 1.00 72.04 ? 346 LYS A CE 1 ATOM 2703 N NZ . LYS A 1 345 ? -33.754 25.955 -61.796 1.00 75.80 ? 346 LYS A NZ 1 ATOM 2704 N N . ILE A 1 346 ? -37.275 32.683 -58.924 1.00 34.55 ? 347 ILE A N 1 ATOM 2705 C CA . ILE A 1 346 ? -37.911 33.967 -58.971 1.00 33.61 ? 347 ILE A CA 1 ATOM 2706 C C . ILE A 1 346 ? -37.025 34.932 -59.798 1.00 33.30 ? 347 ILE A C 1 ATOM 2707 O O . ILE A 1 346 ? -35.841 35.163 -59.504 1.00 29.86 ? 347 ILE A O 1 ATOM 2708 C CB . ILE A 1 346 ? -38.152 34.475 -57.468 1.00 35.19 ? 347 ILE A CB 1 ATOM 2709 C CG1 . ILE A 1 346 ? -39.351 33.774 -56.824 1.00 36.76 ? 347 ILE A CG1 1 ATOM 2710 C CG2 . ILE A 1 346 ? -38.434 35.946 -57.370 1.00 35.42 ? 347 ILE A CG2 1 ATOM 2711 C CD1 . ILE A 1 346 ? -40.557 33.791 -57.730 1.00 38.57 ? 347 ILE A CD1 1 ATOM 2712 N N . SER A 1 347 ? -37.628 35.532 -60.807 1.00 40.26 ? 348 SER A N 1 ATOM 2713 C CA . SER A 1 347 ? -36.942 36.513 -61.601 1.00 47.86 ? 348 SER A CA 1 ATOM 2714 C C . SER A 1 347 ? -36.752 37.744 -60.742 1.00 51.81 ? 348 SER A C 1 ATOM 2715 O O . SER A 1 347 ? -37.367 37.891 -59.680 1.00 49.74 ? 348 SER A O 1 ATOM 2716 C CB . SER A 1 347 ? -37.781 36.846 -62.809 1.00 45.91 ? 348 SER A CB 1 ATOM 2717 O OG . SER A 1 347 ? -38.954 37.480 -62.413 1.00 47.23 ? 348 SER A OG 1 ATOM 2718 N N . ARG A 1 348 ? -35.863 38.605 -61.197 1.00 51.61 ? 349 ARG A N 1 ATOM 2719 C CA . ARG A 1 348 ? -35.590 39.880 -60.562 1.00 48.03 ? 349 ARG A CA 1 ATOM 2720 C C . ARG A 1 348 ? -36.827 40.778 -60.504 1.00 42.59 ? 349 ARG A C 1 ATOM 2721 O O . ARG A 1 348 ? -36.978 41.554 -59.597 1.00 51.90 ? 349 ARG A O 1 ATOM 2722 C CB . ARG A 1 348 ? -34.504 40.581 -61.378 1.00 56.70 ? 349 ARG A CB 1 ATOM 2723 C CG . ARG A 1 348 ? -33.761 41.681 -60.672 1.00 54.57 ? 349 ARG A CG 1 ATOM 2724 C CD . ARG A 1 348 ? -32.757 41.056 -59.746 1.00 60.54 ? 349 ARG A CD 1 ATOM 2725 N NE . ARG A 1 348 ? -32.711 41.900 -58.578 1.00 65.50 ? 349 ARG A NE 1 ATOM 2726 C CZ . ARG A 1 348 ? -32.530 41.502 -57.319 1.00 55.23 ? 349 ARG A CZ 1 ATOM 2727 N NH1 . ARG A 1 348 ? -32.305 40.246 -56.988 1.00 52.83 ? 349 ARG A NH1 1 ATOM 2728 N NH2 . ARG A 1 348 ? -32.550 42.426 -56.380 1.00 59.08 ? 349 ARG A NH2 1 ATOM 2729 N N . GLU A 1 349 ? -37.728 40.648 -61.457 1.00 45.02 ? 350 GLU A N 1 ATOM 2730 C CA . GLU A 1 349 ? -38.885 41.510 -61.555 1.00 48.71 ? 350 GLU A CA 1 ATOM 2731 C C . GLU A 1 349 ? -39.896 41.036 -60.507 1.00 50.29 ? 350 GLU A C 1 ATOM 2732 O O . GLU A 1 349 ? -40.568 41.841 -59.874 1.00 47.20 ? 350 GLU A O 1 ATOM 2733 C CB . GLU A 1 349 ? -39.489 41.504 -63.001 1.00 56.99 ? 350 GLU A CB 1 ATOM 2734 C CG . GLU A 1 349 ? -38.495 41.963 -64.117 1.00 73.56 ? 350 GLU A CG 1 ATOM 2735 C CD . GLU A 1 349 ? -37.345 40.966 -64.428 1.00 82.11 ? 350 GLU A CD 1 ATOM 2736 O OE1 . GLU A 1 349 ? -37.630 39.758 -64.664 1.00 80.75 ? 350 GLU A OE1 1 ATOM 2737 O OE2 . GLU A 1 349 ? -36.145 41.379 -64.436 1.00 84.29 ? 350 GLU A OE2 1 ATOM 2738 N N . ASP A 1 350 ? -40.016 39.718 -60.359 1.00 43.58 ? 351 ASP A N 1 ATOM 2739 C CA . ASP A 1 350 ? -40.873 39.147 -59.350 1.00 42.71 ? 351 ASP A CA 1 ATOM 2740 C C . ASP A 1 350 ? -40.270 39.372 -57.946 1.00 40.22 ? 351 ASP A C 1 ATOM 2741 O O . ASP A 1 350 ? -40.980 39.655 -57.005 1.00 39.61 ? 351 ASP A O 1 ATOM 2742 C CB . ASP A 1 350 ? -41.134 37.680 -59.676 1.00 45.55 ? 351 ASP A CB 1 ATOM 2743 C CG . ASP A 1 350 ? -42.207 37.508 -60.726 1.00 43.71 ? 351 ASP A CG 1 ATOM 2744 O OD1 . ASP A 1 350 ? -42.834 38.515 -61.094 1.00 46.87 ? 351 ASP A OD1 1 ATOM 2745 O OD2 . ASP A 1 350 ? -42.488 36.360 -61.148 1.00 46.01 ? 351 ASP A OD2 1 ATOM 2746 N N . PHE A 1 351 ? -38.961 39.407 -57.836 1.00 35.75 ? 352 PHE A N 1 ATOM 2747 C CA . PHE A 1 351 ? -38.369 39.772 -56.576 1.00 37.23 ? 352 PHE A CA 1 ATOM 2748 C C . PHE A 1 351 ? -38.826 41.145 -56.142 1.00 41.67 ? 352 PHE A C 1 ATOM 2749 O O . PHE A 1 351 ? -39.311 41.317 -55.038 1.00 42.53 ? 352 PHE A O 1 ATOM 2750 C CB . PHE A 1 351 ? -36.877 39.837 -56.698 1.00 36.32 ? 352 PHE A CB 1 ATOM 2751 C CG . PHE A 1 351 ? -36.190 40.033 -55.409 1.00 31.06 ? 352 PHE A CG 1 ATOM 2752 C CD1 . PHE A 1 351 ? -36.034 39.002 -54.553 1.00 30.82 ? 352 PHE A CD1 1 ATOM 2753 C CD2 . PHE A 1 351 ? -35.685 41.241 -55.075 1.00 31.85 ? 352 PHE A CD2 1 ATOM 2754 C CE1 . PHE A 1 351 ? -35.417 39.186 -53.345 1.00 28.94 ? 352 PHE A CE1 1 ATOM 2755 C CE2 . PHE A 1 351 ? -35.034 41.426 -53.895 1.00 30.17 ? 352 PHE A CE2 1 ATOM 2756 C CZ . PHE A 1 351 ? -34.927 40.404 -53.016 1.00 26.34 ? 352 PHE A CZ 1 ATOM 2757 N N . MET A 1 352 ? -38.676 42.113 -57.034 1.00 41.95 ? 353 MET A N 1 ATOM 2758 C CA . MET A 1 352 ? -38.994 43.489 -56.726 1.00 40.22 ? 353 MET A CA 1 ATOM 2759 C C . MET A 1 352 ? -40.452 43.594 -56.396 1.00 38.13 ? 353 MET A C 1 ATOM 2760 O O . MET A 1 352 ? -40.800 44.328 -55.484 1.00 37.52 ? 353 MET A O 1 ATOM 2761 C CB . MET A 1 352 ? -38.615 44.442 -57.876 1.00 42.45 ? 353 MET A CB 1 ATOM 2762 C CG . MET A 1 352 ? -37.090 44.697 -57.980 1.00 57.42 ? 353 MET A CG 1 ATOM 2763 S SD . MET A 1 352 ? -36.478 45.527 -59.517 1.00 77.13 ? 353 MET A SD 1 ATOM 2764 C CE . MET A 1 352 ? -37.916 45.640 -60.627 1.00 62.07 ? 353 MET A CE 1 ATOM 2765 N N . SER A 1 353 ? -41.299 42.894 -57.139 1.00 33.49 ? 354 SER A N 1 ATOM 2766 C CA . SER A 1 353 ? -42.721 42.924 -56.865 1.00 37.97 ? 354 SER A CA 1 ATOM 2767 C C . SER A 1 353 ? -42.987 42.369 -55.451 1.00 39.87 ? 354 SER A C 1 ATOM 2768 O O . SER A 1 353 ? -43.842 42.879 -54.765 1.00 35.93 ? 354 SER A O 1 ATOM 2769 C CB . SER A 1 353 ? -43.498 42.015 -57.810 1.00 38.92 ? 354 SER A CB 1 ATOM 2770 O OG . SER A 1 353 ? -43.638 42.609 -59.052 1.00 48.06 ? 354 SER A OG 1 ATOM 2771 N N . GLY A 1 354 ? -42.271 41.299 -55.073 1.00 33.78 ? 355 GLY A N 1 ATOM 2772 C CA . GLY A 1 354 ? -42.462 40.656 -53.785 1.00 33.73 ? 355 GLY A CA 1 ATOM 2773 C C . GLY A 1 354 ? -42.091 41.581 -52.641 1.00 29.76 ? 355 GLY A C 1 ATOM 2774 O O . GLY A 1 354 ? -42.819 41.717 -51.669 1.00 29.99 ? 355 GLY A O 1 ATOM 2775 N N . VAL A 1 355 ? -40.979 42.267 -52.801 1.00 28.57 ? 356 VAL A N 1 ATOM 2776 C CA . VAL A 1 355 ? -40.535 43.219 -51.810 1.00 30.84 ? 356 VAL A CA 1 ATOM 2777 C C . VAL A 1 355 ? -41.602 44.243 -51.517 1.00 32.30 ? 356 VAL A C 1 ATOM 2778 O O . VAL A 1 355 ? -41.899 44.524 -50.342 1.00 33.38 ? 356 VAL A O 1 ATOM 2779 C CB . VAL A 1 355 ? -39.239 43.901 -52.238 1.00 31.33 ? 356 VAL A CB 1 ATOM 2780 C CG1 . VAL A 1 355 ? -38.895 45.066 -51.336 1.00 32.43 ? 356 VAL A CG1 1 ATOM 2781 C CG2 . VAL A 1 355 ? -38.126 42.885 -52.199 1.00 30.84 ? 356 VAL A CG2 1 ATOM 2782 N N . LYS A 1 356 ? -42.197 44.783 -52.576 1.00 36.95 ? 357 LYS A N 1 ATOM 2783 C CA . LYS A 1 356 ? -43.280 45.747 -52.449 1.00 40.33 ? 357 LYS A CA 1 ATOM 2784 C C . LYS A 1 356 ? -44.432 45.172 -51.632 1.00 34.21 ? 357 LYS A C 1 ATOM 2785 O O . LYS A 1 356 ? -44.884 45.790 -50.668 1.00 33.21 ? 357 LYS A O 1 ATOM 2786 C CB . LYS A 1 356 ? -43.778 46.179 -53.829 1.00 46.30 ? 357 LYS A CB 1 ATOM 2787 C CG . LYS A 1 356 ? -43.743 47.681 -54.060 1.00 55.54 ? 357 LYS A CG 1 ATOM 2788 C CD . LYS A 1 356 ? -45.026 48.343 -53.586 1.00 67.60 ? 357 LYS A CD 1 ATOM 2789 C CE . LYS A 1 356 ? -44.968 49.851 -53.765 1.00 70.30 ? 357 LYS A CE 1 ATOM 2790 N NZ . LYS A 1 356 ? -44.709 50.554 -52.478 1.00 70.82 ? 357 LYS A NZ 1 ATOM 2791 N N . LEU A 1 357 ? -44.905 43.989 -52.015 1.00 31.22 ? 358 LEU A N 1 ATOM 2792 C CA . LEU A 1 357 ? -46.006 43.356 -51.286 1.00 30.48 ? 358 LEU A CA 1 ATOM 2793 C C . LEU A 1 357 ? -45.610 43.110 -49.819 1.00 31.72 ? 358 LEU A C 1 ATOM 2794 O O . LEU A 1 357 ? -46.436 43.148 -48.946 1.00 31.40 ? 358 LEU A O 1 ATOM 2795 C CB . LEU A 1 357 ? -46.406 42.005 -51.919 1.00 30.80 ? 358 LEU A CB 1 ATOM 2796 C CG . LEU A 1 357 ? -46.920 42.037 -53.386 1.00 30.33 ? 358 LEU A CG 1 ATOM 2797 C CD1 . LEU A 1 357 ? -47.020 40.623 -53.984 1.00 28.87 ? 358 LEU A CD1 1 ATOM 2798 C CD2 . LEU A 1 357 ? -48.271 42.730 -53.423 1.00 30.61 ? 358 LEU A CD2 1 ATOM 2799 N N . SER A 1 358 ? -44.342 42.797 -49.580 1.00 31.20 ? 359 SER A N 1 ATOM 2800 C CA . SER A 1 358 ? -43.888 42.366 -48.272 1.00 28.70 ? 359 SER A CA 1 ATOM 2801 C C . SER A 1 358 ? -43.742 43.493 -47.290 1.00 31.33 ? 359 SER A C 1 ATOM 2802 O O . SER A 1 358 ? -43.835 43.261 -46.101 1.00 35.05 ? 359 SER A O 1 ATOM 2803 C CB . SER A 1 358 ? -42.545 41.690 -48.389 1.00 29.70 ? 359 SER A CB 1 ATOM 2804 O OG . SER A 1 358 ? -42.654 40.443 -49.021 1.00 33.11 ? 359 SER A OG 1 ATOM 2805 N N . VAL A 1 359 ? -43.544 44.714 -47.779 1.00 29.16 ? 360 VAL A N 1 ATOM 2806 C CA . VAL A 1 359 ? -43.279 45.850 -46.955 1.00 27.12 ? 360 VAL A CA 1 ATOM 2807 C C . VAL A 1 359 ? -44.163 46.967 -47.433 1.00 30.02 ? 360 VAL A C 1 ATOM 2808 O O . VAL A 1 359 ? -43.686 48.029 -47.897 1.00 30.87 ? 360 VAL A O 1 ATOM 2809 C CB . VAL A 1 359 ? -41.813 46.303 -47.058 1.00 30.47 ? 360 VAL A CB 1 ATOM 2810 C CG1 . VAL A 1 359 ? -41.489 47.257 -45.928 1.00 28.32 ? 360 VAL A CG1 1 ATOM 2811 C CG2 . VAL A 1 359 ? -40.896 45.093 -47.013 1.00 32.73 ? 360 VAL A CG2 1 ATOM 2812 N N . PRO A 1 360 ? -45.462 46.777 -47.265 1.00 32.84 ? 361 PRO A N 1 ATOM 2813 C CA . PRO A 1 360 ? -46.432 47.673 -47.860 1.00 36.76 ? 361 PRO A CA 1 ATOM 2814 C C . PRO A 1 360 ? -46.318 49.121 -47.385 1.00 39.22 ? 361 PRO A C 1 ATOM 2815 O O . PRO A 1 360 ? -46.634 50.060 -48.133 1.00 36.91 ? 361 PRO A O 1 ATOM 2816 C CB . PRO A 1 360 ? -47.783 47.050 -47.444 1.00 40.69 ? 361 PRO A CB 1 ATOM 2817 C CG . PRO A 1 360 ? -47.519 46.144 -46.314 1.00 39.21 ? 361 PRO A CG 1 ATOM 2818 C CD . PRO A 1 360 ? -46.079 45.737 -46.420 1.00 37.52 ? 361 PRO A CD 1 ATOM 2819 N N . HIS A 1 361 ? -45.842 49.296 -46.167 1.00 47.91 ? 362 HIS A N 1 ATOM 2820 C CA . HIS A 1 361 ? -45.771 50.625 -45.583 1.00 64.90 ? 362 HIS A CA 1 ATOM 2821 C C . HIS A 1 361 ? -44.496 51.394 -46.021 1.00 64.31 ? 362 HIS A C 1 ATOM 2822 O O . HIS A 1 361 ? -44.167 52.385 -45.380 1.00 55.94 ? 362 HIS A O 1 ATOM 2823 C CB . HIS A 1 361 ? -45.827 50.550 -44.021 1.00 73.96 ? 362 HIS A CB 1 ATOM 2824 C CG . HIS A 1 361 ? -47.052 49.863 -43.459 1.00 80.98 ? 362 HIS A CG 1 ATOM 2825 N ND1 . HIS A 1 361 ? -48.157 50.557 -43.002 1.00 78.27 ? 362 HIS A ND1 1 ATOM 2826 C CD2 . HIS A 1 361 ? -47.317 48.547 -43.225 1.00 91.25 ? 362 HIS A CD2 1 ATOM 2827 C CE1 . HIS A 1 361 ? -49.050 49.701 -42.527 1.00 84.56 ? 362 HIS A CE1 1 ATOM 2828 N NE2 . HIS A 1 361 ? -48.578 48.472 -42.675 1.00 83.30 ? 362 HIS A NE2 1 ATOM 2829 N N . ALA A 1 362 ? -43.788 50.980 -47.084 1.00 54.45 ? 363 ALA A N 1 ATOM 2830 C CA . ALA A 1 362 ? -42.478 51.577 -47.349 1.00 44.09 ? 363 ALA A CA 1 ATOM 2831 C C . ALA A 1 362 ? -42.408 52.499 -48.542 1.00 37.99 ? 363 ALA A C 1 ATOM 2832 O O . ALA A 1 362 ? -42.760 52.149 -49.632 1.00 42.06 ? 363 ALA A O 1 ATOM 2833 C CB . ALA A 1 362 ? -41.419 50.500 -47.509 1.00 42.88 ? 363 ALA A CB 1 ATOM 2834 N N . ASN A 1 363 ? -41.824 53.661 -48.350 1.00 37.68 ? 364 ASN A N 1 ATOM 2835 C CA . ASN A 1 363 ? -41.405 54.469 -49.488 1.00 38.45 ? 364 ASN A CA 1 ATOM 2836 C C . ASN A 1 363 ? -40.259 53.789 -50.295 1.00 37.98 ? 364 ASN A C 1 ATOM 2837 O O . ASN A 1 363 ? -39.629 52.811 -49.848 1.00 39.63 ? 364 ASN A O 1 ATOM 2838 C CB . ASN A 1 363 ? -41.001 55.857 -48.991 1.00 35.08 ? 364 ASN A CB 1 ATOM 2839 C CG . ASN A 1 363 ? -39.698 55.849 -48.200 1.00 37.69 ? 364 ASN A CG 1 ATOM 2840 O OD1 . ASN A 1 363 ? -38.956 54.875 -48.204 1.00 38.85 ? 364 ASN A OD1 1 ATOM 2841 N ND2 . ASN A 1 363 ? -39.435 56.924 -47.496 1.00 38.19 ? 364 ASN A ND2 1 ATOM 2842 N N . ASP A 1 364 ? -39.986 54.330 -51.467 1.00 39.13 ? 365 ASP A N 1 ATOM 2843 C CA . ASP A 1 364 ? -39.027 53.768 -52.403 1.00 42.50 ? 365 ASP A CA 1 ATOM 2844 C C . ASP A 1 364 ? -37.621 53.614 -51.833 1.00 35.63 ? 365 ASP A C 1 ATOM 2845 O O . ASP A 1 364 ? -36.911 52.662 -52.098 1.00 34.17 ? 365 ASP A O 1 ATOM 2846 C CB . ASP A 1 364 ? -38.963 54.649 -53.677 1.00 54.20 ? 365 ASP A CB 1 ATOM 2847 C CG . ASP A 1 364 ? -40.150 54.431 -54.623 1.00 60.85 ? 365 ASP A CG 1 ATOM 2848 O OD1 . ASP A 1 364 ? -41.011 53.563 -54.349 1.00 61.74 ? 365 ASP A OD1 1 ATOM 2849 O OD2 . ASP A 1 364 ? -40.201 55.117 -55.667 1.00 67.67 ? 365 ASP A OD2 1 ATOM 2850 N N . LEU A 1 365 ? -37.204 54.582 -51.024 1.00 33.39 ? 366 LEU A N 1 ATOM 2851 C CA . LEU A 1 365 ? -35.899 54.494 -50.374 1.00 33.73 ? 366 LEU A CA 1 ATOM 2852 C C . LEU A 1 365 ? -35.880 53.266 -49.469 1.00 30.99 ? 366 LEU A C 1 ATOM 2853 O O . LEU A 1 365 ? -34.896 52.529 -49.404 1.00 29.90 ? 366 LEU A O 1 ATOM 2854 C CB . LEU A 1 365 ? -35.615 55.757 -49.561 1.00 35.79 ? 366 LEU A CB 1 ATOM 2855 C CG . LEU A 1 365 ? -34.160 56.228 -49.525 1.00 42.59 ? 366 LEU A CG 1 ATOM 2856 C CD1 . LEU A 1 365 ? -33.903 57.084 -48.294 1.00 38.63 ? 366 LEU A CD1 1 ATOM 2857 C CD2 . LEU A 1 365 ? -33.210 55.041 -49.565 1.00 39.71 ? 366 LEU A CD2 1 ATOM 2858 N N . GLY A 1 366 ? -36.995 53.068 -48.778 1.00 31.81 ? 367 GLY A N 1 ATOM 2859 C CA . GLY A 1 366 ? -37.236 51.925 -47.919 1.00 28.83 ? 367 GLY A CA 1 ATOM 2860 C C . GLY A 1 366 ? -37.137 50.648 -48.703 1.00 28.11 ? 367 GLY A C 1 ATOM 2861 O O . GLY A 1 366 ? -36.386 49.755 -48.325 1.00 28.34 ? 367 GLY A O 1 ATOM 2862 N N . LEU A 1 367 ? -37.804 50.597 -49.846 1.00 28.17 ? 368 LEU A N 1 ATOM 2863 C CA . LEU A 1 367 ? -37.756 49.388 -50.659 1.00 29.12 ? 368 LEU A CA 1 ATOM 2864 C C . LEU A 1 367 ? -36.353 49.087 -51.134 1.00 31.02 ? 368 LEU A C 1 ATOM 2865 O O . LEU A 1 367 ? -35.924 47.886 -51.174 1.00 30.73 ? 368 LEU A O 1 ATOM 2866 C CB . LEU A 1 367 ? -38.682 49.482 -51.850 1.00 29.94 ? 368 LEU A CB 1 ATOM 2867 C CG . LEU A 1 367 ? -40.195 49.582 -51.475 1.00 36.45 ? 368 LEU A CG 1 ATOM 2868 C CD1 . LEU A 1 367 ? -41.023 49.828 -52.732 1.00 32.20 ? 368 LEU A CD1 1 ATOM 2869 C CD2 . LEU A 1 367 ? -40.713 48.324 -50.707 1.00 34.55 ? 368 LEU A CD2 1 ATOM 2870 N N . ASP A 1 368 ? -35.647 50.141 -51.518 1.00 27.49 ? 369 ASP A N 1 ATOM 2871 C CA . ASP A 1 368 ? -34.265 49.965 -51.956 1.00 33.68 ? 369 ASP A CA 1 ATOM 2872 C C . ASP A 1 368 ? -33.403 49.413 -50.799 1.00 31.74 ? 369 ASP A C 1 ATOM 2873 O O . ASP A 1 368 ? -32.542 48.573 -51.037 1.00 33.57 ? 369 ASP A O 1 ATOM 2874 C CB . ASP A 1 368 ? -33.611 51.278 -52.427 1.00 34.33 ? 369 ASP A CB 1 ATOM 2875 C CG . ASP A 1 368 ? -34.223 51.812 -53.721 1.00 38.14 ? 369 ASP A CG 1 ATOM 2876 O OD1 . ASP A 1 368 ? -34.896 51.058 -54.423 1.00 37.10 ? 369 ASP A OD1 1 ATOM 2877 O OD2 . ASP A 1 368 ? -34.029 52.996 -54.028 1.00 42.52 ? 369 ASP A OD2 1 ATOM 2878 N N . ALA A 1 369 ? -33.613 49.924 -49.593 1.00 26.84 ? 370 ALA A N 1 ATOM 2879 C CA . ALA A 1 369 ? -32.830 49.488 -48.423 1.00 28.89 ? 370 ALA A CA 1 ATOM 2880 C C . ALA A 1 369 ? -33.099 48.029 -48.192 1.00 24.37 ? 370 ALA A C 1 ATOM 2881 O O . ALA A 1 369 ? -32.184 47.268 -48.045 1.00 23.08 ? 370 ALA A O 1 ATOM 2882 C CB . ALA A 1 369 ? -33.154 50.327 -47.180 1.00 30.54 ? 370 ALA A CB 1 ATOM 2883 N N . VAL A 1 370 ? -34.322 47.581 -48.356 1.00 23.88 ? 371 VAL A N 1 ATOM 2884 C CA . VAL A 1 370 ? -34.584 46.125 -48.182 1.00 24.57 ? 371 VAL A CA 1 ATOM 2885 C C . VAL A 1 370 ? -33.857 45.307 -49.239 1.00 25.88 ? 371 VAL A C 1 ATOM 2886 O O . VAL A 1 370 ? -33.095 44.330 -48.962 1.00 31.94 ? 371 VAL A O 1 ATOM 2887 C CB . VAL A 1 370 ? -36.082 45.823 -48.249 1.00 24.79 ? 371 VAL A CB 1 ATOM 2888 C CG1 . VAL A 1 370 ? -36.387 44.327 -48.173 1.00 24.75 ? 371 VAL A CG1 1 ATOM 2889 C CG2 . VAL A 1 370 ? -36.825 46.577 -47.141 1.00 25.86 ? 371 VAL A CG2 1 ATOM 2890 N N . THR A 1 371 ? -34.082 45.694 -50.460 1.00 27.60 ? 372 THR A N 1 ATOM 2891 C CA . THR A 1 371 ? -33.542 44.995 -51.610 1.00 28.92 ? 372 THR A CA 1 ATOM 2892 C C . THR A 1 371 ? -32.042 44.900 -51.524 1.00 25.89 ? 372 THR A C 1 ATOM 2893 O O . THR A 1 371 ? -31.450 43.858 -51.687 1.00 25.09 ? 372 THR A O 1 ATOM 2894 C CB . THR A 1 371 ? -33.916 45.755 -52.896 1.00 35.06 ? 372 THR A CB 1 ATOM 2895 O OG1 . THR A 1 371 ? -35.336 45.796 -53.009 1.00 33.16 ? 372 THR A OG1 1 ATOM 2896 C CG2 . THR A 1 371 ? -33.341 45.077 -54.134 1.00 34.13 ? 372 THR A CG2 1 ATOM 2897 N N . LEU A 1 372 ? -31.401 45.976 -51.156 1.00 27.91 ? 373 LEU A N 1 ATOM 2898 C CA . LEU A 1 372 ? -29.932 45.906 -50.945 1.00 28.51 ? 373 LEU A CA 1 ATOM 2899 C C . LEU A 1 372 ? -29.501 44.946 -49.859 1.00 31.59 ? 373 LEU A C 1 ATOM 2900 O O . LEU A 1 372 ? -28.467 44.284 -49.935 1.00 34.51 ? 373 LEU A O 1 ATOM 2901 C CB . LEU A 1 372 ? -29.440 47.285 -50.579 1.00 29.69 ? 373 LEU A CB 1 ATOM 2902 C CG . LEU A 1 372 ? -27.978 47.321 -50.259 1.00 31.79 ? 373 LEU A CG 1 ATOM 2903 C CD1 . LEU A 1 372 ? -27.138 46.831 -51.437 1.00 38.68 ? 373 LEU A CD1 1 ATOM 2904 C CD2 . LEU A 1 372 ? -27.611 48.728 -49.950 1.00 34.62 ? 373 LEU A CD2 1 ATOM 2905 N N . GLN A 1 373 ? -30.286 44.910 -48.790 1.00 32.12 ? 374 GLN A N 1 ATOM 2906 C CA . GLN A 1 373 ? -29.903 44.168 -47.649 1.00 30.64 ? 374 GLN A CA 1 ATOM 2907 C C . GLN A 1 373 ? -30.001 42.703 -47.953 1.00 30.28 ? 374 GLN A C 1 ATOM 2908 O O . GLN A 1 373 ? -29.343 41.926 -47.348 1.00 34.08 ? 374 GLN A O 1 ATOM 2909 C CB . GLN A 1 373 ? -30.862 44.544 -46.522 1.00 35.69 ? 374 GLN A CB 1 ATOM 2910 C CG . GLN A 1 373 ? -30.545 43.923 -45.204 1.00 34.54 ? 374 GLN A CG 1 ATOM 2911 C CD . GLN A 1 373 ? -29.331 44.575 -44.598 1.00 37.34 ? 374 GLN A CD 1 ATOM 2912 O OE1 . GLN A 1 373 ? -28.829 45.613 -45.074 1.00 39.94 ? 374 GLN A OE1 1 ATOM 2913 N NE2 . GLN A 1 373 ? -28.806 43.932 -43.606 1.00 35.09 ? 374 GLN A NE2 1 ATOM 2914 N N . TYR A 1 374 ? -30.863 42.303 -48.869 1.00 31.60 ? 375 TYR A N 1 ATOM 2915 C CA . TYR A 1 374 ? -31.130 40.877 -49.105 1.00 28.69 ? 375 TYR A CA 1 ATOM 2916 C C . TYR A 1 374 ? -30.686 40.386 -50.517 1.00 32.95 ? 375 TYR A C 1 ATOM 2917 O O . TYR A 1 374 ? -30.995 39.298 -50.943 1.00 29.22 ? 375 TYR A O 1 ATOM 2918 C CB . TYR A 1 374 ? -32.645 40.632 -48.955 1.00 29.52 ? 375 TYR A CB 1 ATOM 2919 C CG . TYR A 1 374 ? -33.097 40.510 -47.499 1.00 29.29 ? 375 TYR A CG 1 ATOM 2920 C CD1 . TYR A 1 374 ? -33.499 41.645 -46.764 1.00 26.96 ? 375 TYR A CD1 1 ATOM 2921 C CD2 . TYR A 1 374 ? -33.104 39.259 -46.862 1.00 28.57 ? 375 TYR A CD2 1 ATOM 2922 C CE1 . TYR A 1 374 ? -33.854 41.545 -45.453 1.00 27.22 ? 375 TYR A CE1 1 ATOM 2923 C CE2 . TYR A 1 374 ? -33.451 39.149 -45.526 1.00 27.64 ? 375 TYR A CE2 1 ATOM 2924 C CZ . TYR A 1 374 ? -33.833 40.286 -44.834 1.00 29.08 ? 375 TYR A CZ 1 ATOM 2925 O OH . TYR A 1 374 ? -34.240 40.161 -43.546 1.00 26.52 ? 375 TYR A OH 1 ATOM 2926 N N . THR A 1 375 ? -29.969 41.188 -51.266 1.00 36.96 ? 376 THR A N 1 ATOM 2927 C CA . THR A 1 375 ? -29.605 40.778 -52.608 1.00 33.63 ? 376 THR A CA 1 ATOM 2928 C C . THR A 1 375 ? -28.130 40.534 -52.576 1.00 33.43 ? 376 THR A C 1 ATOM 2929 O O . THR A 1 375 ? -27.376 41.417 -52.182 1.00 33.18 ? 376 THR A O 1 ATOM 2930 C CB . THR A 1 375 ? -29.822 41.942 -53.597 1.00 33.61 ? 376 THR A CB 1 ATOM 2931 O OG1 . THR A 1 375 ? -31.217 42.269 -53.634 1.00 32.24 ? 376 THR A OG1 1 ATOM 2932 C CG2 . THR A 1 375 ? -29.339 41.584 -54.980 1.00 31.22 ? 376 THR A CG2 1 ATOM 2933 N N . ASP A 1 376 ? -27.729 39.371 -53.058 1.00 33.56 ? 377 ASP A N 1 ATOM 2934 C CA . ASP A 1 376 ? -26.330 39.087 -53.377 1.00 39.21 ? 377 ASP A CA 1 ATOM 2935 C C . ASP A 1 376 ? -25.988 39.701 -54.734 1.00 39.76 ? 377 ASP A C 1 ATOM 2936 O O . ASP A 1 376 ? -26.411 39.145 -55.752 1.00 38.21 ? 377 ASP A O 1 ATOM 2937 C CB . ASP A 1 376 ? -26.125 37.566 -53.453 1.00 39.17 ? 377 ASP A CB 1 ATOM 2938 C CG . ASP A 1 376 ? -24.692 37.207 -53.795 1.00 40.67 ? 377 ASP A CG 1 ATOM 2939 O OD1 . ASP A 1 376 ? -23.936 38.131 -54.158 1.00 35.82 ? 377 ASP A OD1 1 ATOM 2940 O OD2 . ASP A 1 376 ? -24.339 36.014 -53.695 1.00 36.15 ? 377 ASP A OD2 1 ATOM 2941 N N . TRP A 1 377 ? -25.273 40.832 -54.758 1.00 38.71 ? 378 TRP A N 1 ATOM 2942 C CA . TRP A 1 377 ? -24.932 41.540 -56.030 1.00 43.73 ? 378 TRP A CA 1 ATOM 2943 C C . TRP A 1 377 ? -23.858 40.870 -56.934 1.00 39.54 ? 378 TRP A C 1 ATOM 2944 O O . TRP A 1 377 ? -23.625 41.329 -58.021 1.00 42.39 ? 378 TRP A O 1 ATOM 2945 C CB . TRP A 1 377 ? -24.588 43.047 -55.790 1.00 45.17 ? 378 TRP A CB 1 ATOM 2946 C CG . TRP A 1 377 ? -25.834 43.817 -55.441 1.00 47.07 ? 378 TRP A CG 1 ATOM 2947 C CD1 . TRP A 1 377 ? -26.137 44.304 -54.246 1.00 47.52 ? 378 TRP A CD1 1 ATOM 2948 C CD2 . TRP A 1 377 ? -26.982 44.062 -56.285 1.00 47.17 ? 378 TRP A CD2 1 ATOM 2949 N NE1 . TRP A 1 377 ? -27.388 44.856 -54.259 1.00 51.89 ? 378 TRP A NE1 1 ATOM 2950 C CE2 . TRP A 1 377 ? -27.925 44.732 -55.506 1.00 47.69 ? 378 TRP A CE2 1 ATOM 2951 C CE3 . TRP A 1 377 ? -27.300 43.751 -57.614 1.00 62.81 ? 378 TRP A CE3 1 ATOM 2952 C CZ2 . TRP A 1 377 ? -29.189 45.135 -55.993 1.00 59.19 ? 378 TRP A CZ2 1 ATOM 2953 C CZ3 . TRP A 1 377 ? -28.559 44.160 -58.125 1.00 68.52 ? 378 TRP A CZ3 1 ATOM 2954 C CH2 . TRP A 1 377 ? -29.484 44.845 -57.304 1.00 62.22 ? 378 TRP A CH2 1 ATOM 2955 N N . MET A 1 378 ? -23.240 39.791 -56.500 1.00 40.95 ? 379 MET A N 1 ATOM 2956 C CA . MET A 1 378 ? -22.353 38.997 -57.354 1.00 42.54 ? 379 MET A CA 1 ATOM 2957 C C . MET A 1 378 ? -23.183 37.965 -58.130 1.00 48.25 ? 379 MET A C 1 ATOM 2958 O O . MET A 1 378 ? -22.659 37.248 -58.983 1.00 44.55 ? 379 MET A O 1 ATOM 2959 C CB . MET A 1 378 ? -21.324 38.210 -56.514 1.00 41.74 ? 379 MET A CB 1 ATOM 2960 C CG . MET A 1 378 ? -20.374 39.034 -55.640 1.00 52.67 ? 379 MET A CG 1 ATOM 2961 S SD . MET A 1 378 ? -19.230 38.035 -54.613 1.00 63.22 ? 379 MET A SD 1 ATOM 2962 C CE . MET A 1 378 ? -18.346 37.215 -55.970 1.00 63.68 ? 379 MET A CE 1 ATOM 2963 N N . ASP A 1 379 ? -24.451 37.825 -57.778 1.00 45.59 ? 380 ASP A N 1 ATOM 2964 C CA . ASP A 1 379 ? -25.281 36.795 -58.384 1.00 40.71 ? 380 ASP A CA 1 ATOM 2965 C C . ASP A 1 379 ? -26.725 37.194 -58.205 1.00 40.86 ? 380 ASP A C 1 ATOM 2966 O O . ASP A 1 379 ? -27.493 36.526 -57.512 1.00 43.61 ? 380 ASP A O 1 ATOM 2967 C CB . ASP A 1 379 ? -25.021 35.438 -57.728 1.00 42.42 ? 380 ASP A CB 1 ATOM 2968 C CG . ASP A 1 379 ? -25.499 34.278 -58.579 1.00 46.79 ? 380 ASP A CG 1 ATOM 2969 O OD1 . ASP A 1 379 ? -25.840 34.506 -59.759 1.00 49.19 ? 380 ASP A OD1 1 ATOM 2970 O OD2 . ASP A 1 379 ? -25.534 33.139 -58.069 1.00 45.75 ? 380 ASP A OD2 1 ATOM 2971 N N . ASP A 1 380 ? -27.084 38.306 -58.829 1.00 46.83 ? 381 ASP A N 1 ATOM 2972 C CA . ASP A 1 380 ? -28.413 38.920 -58.598 1.00 52.08 ? 381 ASP A CA 1 ATOM 2973 C C . ASP A 1 380 ? -29.544 38.308 -59.455 1.00 57.26 ? 381 ASP A C 1 ATOM 2974 O O . ASP A 1 380 ? -30.746 38.638 -59.259 1.00 59.49 ? 381 ASP A O 1 ATOM 2975 C CB . ASP A 1 380 ? -28.352 40.470 -58.788 1.00 53.28 ? 381 ASP A CB 1 ATOM 2976 C CG . ASP A 1 380 ? -28.043 40.878 -60.228 1.00 54.94 ? 381 ASP A CG 1 ATOM 2977 O OD1 . ASP A 1 380 ? -26.881 40.708 -60.699 1.00 54.24 ? 381 ASP A OD1 1 ATOM 2978 O OD2 . ASP A 1 380 ? -28.993 41.340 -60.876 1.00 66.97 ? 381 ASP A OD2 1 ATOM 2979 N N . ASN A 1 381 ? -29.164 37.423 -60.383 1.00 55.12 ? 382 ASN A N 1 ATOM 2980 C CA . ASN A 1 381 ? -30.135 36.646 -61.174 1.00 56.32 ? 382 ASN A CA 1 ATOM 2981 C C . ASN A 1 381 ? -30.289 35.187 -60.808 1.00 48.72 ? 382 ASN A C 1 ATOM 2982 O O . ASN A 1 381 ? -30.965 34.434 -61.502 1.00 52.78 ? 382 ASN A O 1 ATOM 2983 C CB . ASN A 1 381 ? -29.797 36.745 -62.661 1.00 58.92 ? 382 ASN A CB 1 ATOM 2984 C CG . ASN A 1 381 ? -30.380 37.976 -63.259 1.00 54.72 ? 382 ASN A CG 1 ATOM 2985 O OD1 . ASN A 1 381 ? -31.585 38.217 -63.168 1.00 63.36 ? 382 ASN A OD1 1 ATOM 2986 N ND2 . ASN A 1 381 ? -29.537 38.806 -63.770 1.00 55.72 ? 382 ASN A ND2 1 ATOM 2987 N N . ASN A 1 382 ? -29.677 34.772 -59.719 1.00 41.24 ? 383 ASN A N 1 ATOM 2988 C CA . ASN A 1 382 ? -29.949 33.455 -59.225 1.00 41.76 ? 383 ASN A CA 1 ATOM 2989 C C . ASN A 1 382 ? -31.403 33.375 -58.661 1.00 41.74 ? 383 ASN A C 1 ATOM 2990 O O . ASN A 1 382 ? -31.759 34.030 -57.667 1.00 41.78 ? 383 ASN A O 1 ATOM 2991 C CB . ASN A 1 382 ? -28.895 33.161 -58.196 1.00 47.28 ? 383 ASN A CB 1 ATOM 2992 C CG . ASN A 1 382 ? -29.039 31.815 -57.646 1.00 45.82 ? 383 ASN A CG 1 ATOM 2993 O OD1 . ASN A 1 382 ? -30.137 31.311 -57.597 1.00 47.54 ? 383 ASN A OD1 1 ATOM 2994 N ND2 . ASN A 1 382 ? -27.944 31.217 -57.222 1.00 45.04 ? 383 ASN A ND2 1 ATOM 2995 N N . GLY A 1 383 ? -32.244 32.604 -59.335 1.00 36.99 ? 384 GLY A N 1 ATOM 2996 C CA . GLY A 1 383 ? -33.666 32.501 -59.042 1.00 36.85 ? 384 GLY A CA 1 ATOM 2997 C C . GLY A 1 383 ? -33.970 31.848 -57.706 1.00 36.10 ? 384 GLY A C 1 ATOM 2998 O O . GLY A 1 383 ? -35.028 32.096 -57.089 1.00 34.18 ? 384 GLY A O 1 ATOM 2999 N N . ILE A 1 384 ? -33.050 31.026 -57.267 1.00 31.17 ? 385 ILE A N 1 ATOM 3000 C CA . ILE A 1 384 ? -33.149 30.401 -55.987 1.00 34.47 ? 385 ILE A CA 1 ATOM 3001 C C . ILE A 1 384 ? -32.819 31.394 -54.860 1.00 38.91 ? 385 ILE A C 1 ATOM 3002 O O . ILE A 1 384 ? -33.514 31.416 -53.849 1.00 34.89 ? 385 ILE A O 1 ATOM 3003 C CB . ILE A 1 384 ? -32.235 29.214 -55.932 1.00 35.40 ? 385 ILE A CB 1 ATOM 3004 C CG1 . ILE A 1 384 ? -32.888 28.075 -56.752 1.00 42.76 ? 385 ILE A CG1 1 ATOM 3005 C CG2 . ILE A 1 384 ? -31.985 28.752 -54.499 1.00 34.96 ? 385 ILE A CG2 1 ATOM 3006 C CD1 . ILE A 1 384 ? -31.937 26.911 -57.004 1.00 42.11 ? 385 ILE A CD1 1 ATOM 3007 N N . LYS A 1 385 ? -31.806 32.234 -55.075 1.00 37.75 ? 386 LYS A N 1 ATOM 3008 C CA . LYS A 1 385 ? -31.381 33.222 -54.106 1.00 40.14 ? 386 LYS A CA 1 ATOM 3009 C C . LYS A 1 385 ? -32.432 34.300 -53.929 1.00 39.68 ? 386 LYS A C 1 ATOM 3010 O O . LYS A 1 385 ? -32.679 34.727 -52.810 1.00 41.03 ? 386 LYS A O 1 ATOM 3011 C CB . LYS A 1 385 ? -30.040 33.844 -54.484 1.00 39.67 ? 386 LYS A CB 1 ATOM 3012 C CG . LYS A 1 385 ? -28.863 33.072 -53.906 1.00 43.32 ? 386 LYS A CG 1 ATOM 3013 C CD . LYS A 1 385 ? -27.560 33.448 -54.569 1.00 45.75 ? 386 LYS A CD 1 ATOM 3014 C CE . LYS A 1 385 ? -26.345 32.701 -53.963 1.00 49.44 ? 386 LYS A CE 1 ATOM 3015 N NZ . LYS A 1 385 ? -25.096 33.294 -54.585 1.00 49.83 ? 386 LYS A NZ 1 ATOM 3016 N N . ASN A 1 386 ? -33.041 34.701 -55.033 1.00 34.10 ? 387 ASN A N 1 ATOM 3017 C CA . ASN A 1 386 ? -34.131 35.580 -55.008 1.00 34.53 ? 387 ASN A CA 1 ATOM 3018 C C . ASN A 1 386 ? -35.346 34.967 -54.280 1.00 33.26 ? 387 ASN A C 1 ATOM 3019 O O . ASN A 1 386 ? -36.021 35.640 -53.541 1.00 31.04 ? 387 ASN A O 1 ATOM 3020 C CB . ASN A 1 386 ? -34.526 35.999 -56.419 1.00 35.68 ? 387 ASN A CB 1 ATOM 3021 C CG . ASN A 1 386 ? -33.474 36.874 -57.138 1.00 40.51 ? 387 ASN A CG 1 ATOM 3022 O OD1 . ASN A 1 386 ? -32.482 37.343 -56.593 1.00 36.74 ? 387 ASN A OD1 1 ATOM 3023 N ND2 . ASN A 1 386 ? -33.711 37.062 -58.411 1.00 47.50 ? 387 ASN A ND2 1 ATOM 3024 N N . ARG A 1 387 ? -35.656 33.716 -54.546 1.00 29.61 ? 388 ARG A N 1 ATOM 3025 C CA . ARG A 1 387 ? -36.784 33.058 -53.907 1.00 28.92 ? 388 ARG A CA 1 ATOM 3026 C C . ARG A 1 387 ? -36.531 32.992 -52.384 1.00 29.47 ? 388 ARG A C 1 ATOM 3027 O O . ARG A 1 387 ? -37.288 33.595 -51.604 1.00 28.04 ? 388 ARG A O 1 ATOM 3028 C CB . ARG A 1 387 ? -36.974 31.704 -54.503 1.00 29.11 ? 388 ARG A CB 1 ATOM 3029 C CG . ARG A 1 387 ? -38.136 30.862 -54.015 1.00 31.10 ? 388 ARG A CG 1 ATOM 3030 C CD . ARG A 1 387 ? -37.579 29.627 -53.325 1.00 33.10 ? 388 ARG A CD 1 ATOM 3031 N NE . ARG A 1 387 ? -37.384 28.566 -54.197 1.00 35.16 ? 388 ARG A NE 1 ATOM 3032 C CZ . ARG A 1 387 ? -36.424 27.646 -54.115 1.00 33.07 ? 388 ARG A CZ 1 ATOM 3033 N NH1 . ARG A 1 387 ? -35.465 27.654 -53.210 1.00 29.87 ? 388 ARG A NH1 1 ATOM 3034 N NH2 . ARG A 1 387 ? -36.433 26.721 -55.040 1.00 34.03 ? 388 ARG A NH2 1 ATOM 3035 N N . ASP A 1 388 ? -35.416 32.396 -52.001 1.00 28.48 ? 389 ASP A N 1 ATOM 3036 C CA . ASP A 1 388 ? -35.022 32.272 -50.604 1.00 30.96 ? 389 ASP A CA 1 ATOM 3037 C C . ASP A 1 388 ? -34.893 33.600 -49.882 1.00 34.08 ? 389 ASP A C 1 ATOM 3038 O O . ASP A 1 388 ? -35.333 33.699 -48.691 1.00 31.91 ? 389 ASP A O 1 ATOM 3039 C CB . ASP A 1 388 ? -33.760 31.445 -50.452 1.00 29.20 ? 389 ASP A CB 1 ATOM 3040 C CG . ASP A 1 388 ? -33.979 30.002 -50.859 1.00 30.96 ? 389 ASP A CG 1 ATOM 3041 O OD1 . ASP A 1 388 ? -35.150 29.594 -50.996 1.00 28.09 ? 389 ASP A OD1 1 ATOM 3042 O OD2 . ASP A 1 388 ? -32.989 29.325 -51.095 1.00 33.90 ? 389 ASP A OD2 1 ATOM 3043 N N . GLY A 1 389 ? -34.414 34.616 -50.614 1.00 32.43 ? 390 GLY A N 1 ATOM 3044 C CA . GLY A 1 389 ? -34.174 35.927 -50.045 1.00 30.83 ? 390 GLY A CA 1 ATOM 3045 C C . GLY A 1 389 ? -35.527 36.579 -49.723 1.00 34.11 ? 390 GLY A C 1 ATOM 3046 O O . GLY A 1 389 ? -35.717 37.183 -48.673 1.00 32.74 ? 390 GLY A O 1 ATOM 3047 N N . LEU A 1 390 ? -36.500 36.391 -50.589 1.00 29.60 ? 391 LEU A N 1 ATOM 3048 C CA . LEU A 1 390 ? -37.821 36.925 -50.334 1.00 30.63 ? 391 LEU A CA 1 ATOM 3049 C C . LEU A 1 390 ? -38.514 36.130 -49.180 1.00 28.00 ? 391 LEU A C 1 ATOM 3050 O O . LEU A 1 390 ? -39.197 36.682 -48.335 1.00 29.48 ? 391 LEU A O 1 ATOM 3051 C CB . LEU A 1 390 ? -38.593 36.854 -51.616 1.00 30.47 ? 391 LEU A CB 1 ATOM 3052 C CG . LEU A 1 390 ? -39.672 37.801 -52.057 1.00 40.48 ? 391 LEU A CG 1 ATOM 3053 C CD1 . LEU A 1 390 ? -39.585 39.244 -51.534 1.00 39.83 ? 391 LEU A CD1 1 ATOM 3054 C CD2 . LEU A 1 390 ? -39.698 37.771 -53.587 1.00 38.49 ? 391 LEU A CD2 1 ATOM 3055 N N . ASP A 1 391 ? -38.325 34.842 -49.154 1.00 26.50 ? 392 ASP A N 1 ATOM 3056 C CA . ASP A 1 391 ? -38.771 34.041 -48.046 1.00 29.81 ? 392 ASP A CA 1 ATOM 3057 C C . ASP A 1 391 ? -38.220 34.600 -46.689 1.00 27.73 ? 392 ASP A C 1 ATOM 3058 O O . ASP A 1 391 ? -38.993 34.839 -45.786 1.00 28.54 ? 392 ASP A O 1 ATOM 3059 C CB . ASP A 1 391 ? -38.350 32.600 -48.288 1.00 31.35 ? 392 ASP A CB 1 ATOM 3060 C CG . ASP A 1 391 ? -39.102 31.618 -47.441 1.00 38.38 ? 392 ASP A CG 1 ATOM 3061 O OD1 . ASP A 1 391 ? -39.815 32.024 -46.495 1.00 41.45 ? 392 ASP A OD1 1 ATOM 3062 O OD2 . ASP A 1 391 ? -39.004 30.414 -47.771 1.00 41.88 ? 392 ASP A OD2 1 ATOM 3063 N N . ASP A 1 392 ? -36.931 34.890 -46.594 1.00 25.85 ? 393 ASP A N 1 ATOM 3064 C CA . ASP A 1 392 ? -36.339 35.547 -45.432 1.00 25.55 ? 393 ASP A CA 1 ATOM 3065 C C . ASP A 1 392 ? -36.903 36.937 -45.141 1.00 29.65 ? 393 ASP A C 1 ATOM 3066 O O . ASP A 1 392 ? -37.115 37.300 -43.964 1.00 27.80 ? 393 ASP A O 1 ATOM 3067 C CB . ASP A 1 392 ? -34.827 35.632 -45.607 1.00 27.72 ? 393 ASP A CB 1 ATOM 3068 C CG . ASP A 1 392 ? -34.142 34.260 -45.513 1.00 30.86 ? 393 ASP A CG 1 ATOM 3069 O OD1 . ASP A 1 392 ? -34.705 33.403 -44.881 1.00 34.10 ? 393 ASP A OD1 1 ATOM 3070 O OD2 . ASP A 1 392 ? -33.023 34.045 -46.014 1.00 37.31 ? 393 ASP A OD2 1 ATOM 3071 N N . ILE A 1 393 ? -37.155 37.733 -46.187 1.00 26.83 ? 394 ILE A N 1 ATOM 3072 C CA . ILE A 1 393 ? -37.731 39.047 -45.954 1.00 26.85 ? 394 ILE A CA 1 ATOM 3073 C C . ILE A 1 393 ? -39.107 38.922 -45.249 1.00 25.44 ? 394 ILE A C 1 ATOM 3074 O O . ILE A 1 393 ? -39.365 39.580 -44.286 1.00 26.48 ? 394 ILE A O 1 ATOM 3075 C CB . ILE A 1 393 ? -37.863 39.845 -47.248 1.00 26.87 ? 394 ILE A CB 1 ATOM 3076 C CG1 . ILE A 1 393 ? -36.468 40.260 -47.789 1.00 32.03 ? 394 ILE A CG1 1 ATOM 3077 C CG2 . ILE A 1 393 ? -38.812 41.020 -47.142 1.00 23.38 ? 394 ILE A CG2 1 ATOM 3078 C CD1 . ILE A 1 393 ? -36.529 40.685 -49.270 1.00 32.79 ? 394 ILE A CD1 1 ATOM 3079 N N . VAL A 1 394 ? -39.974 38.078 -45.723 1.00 22.78 ? 395 VAL A N 1 ATOM 3080 C CA . VAL A 1 394 ? -41.301 38.006 -45.179 1.00 24.15 ? 395 VAL A CA 1 ATOM 3081 C C . VAL A 1 394 ? -41.298 37.505 -43.721 1.00 24.84 ? 395 VAL A C 1 ATOM 3082 O O . VAL A 1 394 ? -41.945 38.074 -42.857 1.00 22.35 ? 395 VAL A O 1 ATOM 3083 C CB . VAL A 1 394 ? -42.159 37.108 -46.082 1.00 26.01 ? 395 VAL A CB 1 ATOM 3084 C CG1 . VAL A 1 394 ? -43.527 36.900 -45.506 1.00 26.07 ? 395 VAL A CG1 1 ATOM 3085 C CG2 . VAL A 1 394 ? -42.331 37.743 -47.486 1.00 26.46 ? 395 VAL A CG2 1 ATOM 3086 N N . GLY A 1 395 ? -40.482 36.482 -43.464 1.00 26.75 ? 396 GLY A N 1 ATOM 3087 C CA . GLY A 1 395 ? -40.314 35.878 -42.170 1.00 24.63 ? 396 GLY A CA 1 ATOM 3088 C C . GLY A 1 395 ? -39.607 36.785 -41.191 1.00 25.54 ? 396 GLY A C 1 ATOM 3089 O O . GLY A 1 395 ? -40.079 36.958 -40.091 1.00 29.85 ? 396 GLY A O 1 ATOM 3090 N N . ASP A 1 396 ? -38.534 37.449 -41.605 1.00 26.60 ? 397 ASP A N 1 ATOM 3091 C CA . ASP A 1 396 ? -37.797 38.312 -40.725 1.00 22.49 ? 397 ASP A CA 1 ATOM 3092 C C . ASP A 1 396 ? -38.658 39.467 -40.299 1.00 24.50 ? 397 ASP A C 1 ATOM 3093 O O . ASP A 1 396 ? -38.752 39.779 -39.129 1.00 25.24 ? 397 ASP A O 1 ATOM 3094 C CB . ASP A 1 396 ? -36.588 38.846 -41.391 1.00 26.35 ? 397 ASP A CB 1 ATOM 3095 C CG . ASP A 1 396 ? -35.507 37.792 -41.602 1.00 27.98 ? 397 ASP A CG 1 ATOM 3096 O OD1 . ASP A 1 396 ? -35.640 36.674 -41.053 1.00 24.55 ? 397 ASP A OD1 1 ATOM 3097 O OD2 . ASP A 1 396 ? -34.531 38.114 -42.313 1.00 23.78 ? 397 ASP A OD2 1 ATOM 3098 N N . HIS A 1 397 ? -39.285 40.110 -41.253 1.00 22.77 ? 398 HIS A N 1 ATOM 3099 C CA . HIS A 1 397 ? -40.053 41.292 -40.999 1.00 23.72 ? 398 HIS A CA 1 ATOM 3100 C C . HIS A 1 397 ? -41.339 41.050 -40.186 1.00 27.65 ? 398 HIS A C 1 ATOM 3101 O O . HIS A 1 397 ? -41.705 41.910 -39.389 1.00 29.27 ? 398 HIS A O 1 ATOM 3102 C CB . HIS A 1 397 ? -40.461 41.902 -42.321 1.00 22.93 ? 398 HIS A CB 1 ATOM 3103 C CG . HIS A 1 397 ? -41.438 43.013 -42.215 1.00 24.16 ? 398 HIS A CG 1 ATOM 3104 N ND1 . HIS A 1 397 ? -41.222 44.127 -41.441 1.00 25.69 ? 398 HIS A ND1 1 ATOM 3105 C CD2 . HIS A 1 397 ? -42.572 43.258 -42.891 1.00 29.74 ? 398 HIS A CD2 1 ATOM 3106 C CE1 . HIS A 1 397 ? -42.207 44.979 -41.578 1.00 25.03 ? 398 HIS A CE1 1 ATOM 3107 N NE2 . HIS A 1 397 ? -43.041 44.479 -42.466 1.00 31.46 ? 398 HIS A NE2 1 ATOM 3108 N N . ASN A 1 398 ? -42.005 39.918 -40.425 1.00 25.29 ? 399 ASN A N 1 ATOM 3109 C CA . ASN A 1 398 ? -43.264 39.637 -39.850 1.00 24.83 ? 399 ASN A CA 1 ATOM 3110 C C . ASN A 1 398 ? -43.285 38.777 -38.580 1.00 25.81 ? 399 ASN A C 1 ATOM 3111 O O . ASN A 1 398 ? -44.244 38.859 -37.823 1.00 26.70 ? 399 ASN A O 1 ATOM 3112 C CB . ASN A 1 398 ? -44.149 38.969 -40.858 1.00 24.60 ? 399 ASN A CB 1 ATOM 3113 C CG . ASN A 1 398 ? -44.679 39.955 -41.907 1.00 25.59 ? 399 ASN A CG 1 ATOM 3114 O OD1 . ASN A 1 398 ? -45.476 40.834 -41.589 1.00 25.93 ? 399 ASN A OD1 1 ATOM 3115 N ND2 . ASN A 1 398 ? -44.275 39.774 -43.163 1.00 22.30 ? 399 ASN A ND2 1 ATOM 3116 N N . VAL A 1 399 ? -42.282 37.951 -38.386 1.00 23.00 ? 400 VAL A N 1 ATOM 3117 C CA . VAL A 1 399 ? -42.294 36.990 -37.342 1.00 22.42 ? 400 VAL A CA 1 ATOM 3118 C C . VAL A 1 399 ? -40.996 37.045 -36.508 1.00 23.51 ? 400 VAL A C 1 ATOM 3119 O O . VAL A 1 399 ? -40.986 37.446 -35.341 1.00 25.24 ? 400 VAL A O 1 ATOM 3120 C CB . VAL A 1 399 ? -42.501 35.596 -37.884 1.00 22.82 ? 400 VAL A CB 1 ATOM 3121 C CG1 . VAL A 1 399 ? -42.511 34.615 -36.736 1.00 24.52 ? 400 VAL A CG1 1 ATOM 3122 C CG2 . VAL A 1 399 ? -43.846 35.491 -38.641 1.00 24.84 ? 400 VAL A CG2 1 ATOM 3123 N N . ILE A 1 400 ? -39.876 36.857 -37.140 1.00 25.71 ? 401 ILE A N 1 ATOM 3124 C CA . ILE A 1 400 ? -38.646 36.694 -36.394 1.00 27.01 ? 401 ILE A CA 1 ATOM 3125 C C . ILE A 1 400 ? -38.155 37.938 -35.737 1.00 27.22 ? 401 ILE A C 1 ATOM 3126 O O . ILE A 1 400 ? -37.854 37.929 -34.538 1.00 27.61 ? 401 ILE A O 1 ATOM 3127 C CB . ILE A 1 400 ? -37.566 36.067 -37.236 1.00 26.22 ? 401 ILE A CB 1 ATOM 3128 C CG1 . ILE A 1 400 ? -38.063 34.680 -37.752 1.00 28.10 ? 401 ILE A CG1 1 ATOM 3129 C CG2 . ILE A 1 400 ? -36.312 35.913 -36.404 1.00 26.20 ? 401 ILE A CG2 1 ATOM 3130 C CD1 . ILE A 1 400 ? -36.968 33.922 -38.546 1.00 29.66 ? 401 ILE A CD1 1 ATOM 3131 N N . CYS A 1 401 ? -38.085 39.032 -36.473 1.00 26.22 ? 402 CYS A N 1 ATOM 3132 C CA . CYS A 1 401 ? -37.523 40.247 -35.872 1.00 23.46 ? 402 CYS A CA 1 ATOM 3133 C C . CYS A 1 401 ? -38.513 40.919 -34.895 1.00 24.78 ? 402 CYS A C 1 ATOM 3134 O O . CYS A 1 401 ? -38.111 41.448 -33.904 1.00 23.03 ? 402 CYS A O 1 ATOM 3135 C CB . CYS A 1 401 ? -37.032 41.220 -36.955 1.00 24.17 ? 402 CYS A CB 1 ATOM 3136 S SG . CYS A 1 401 ? -35.654 40.455 -37.860 1.00 28.98 ? 402 CYS A SG 1 ATOM 3137 N N . PRO A 1 402 ? -39.812 40.939 -35.187 1.00 24.91 ? 403 PRO A N 1 ATOM 3138 C CA . PRO A 1 402 ? -40.690 41.386 -34.094 1.00 25.11 ? 403 PRO A CA 1 ATOM 3139 C C . PRO A 1 402 ? -40.506 40.512 -32.836 1.00 28.06 ? 403 PRO A C 1 ATOM 3140 O O . PRO A 1 402 ? -40.443 41.022 -31.713 1.00 25.99 ? 403 PRO A O 1 ATOM 3141 C CB . PRO A 1 402 ? -42.089 41.142 -34.664 1.00 25.02 ? 403 PRO A CB 1 ATOM 3142 C CG . PRO A 1 402 ? -41.898 41.396 -36.142 1.00 26.69 ? 403 PRO A CG 1 ATOM 3143 C CD . PRO A 1 402 ? -40.550 40.711 -36.435 1.00 24.67 ? 403 PRO A CD 1 ATOM 3144 N N . LEU A 1 403 ? -40.392 39.210 -33.016 1.00 25.86 ? 404 LEU A N 1 ATOM 3145 C CA . LEU A 1 403 ? -40.292 38.370 -31.866 1.00 27.09 ? 404 LEU A CA 1 ATOM 3146 C C . LEU A 1 403 ? -38.962 38.657 -31.127 1.00 31.11 ? 404 LEU A C 1 ATOM 3147 O O . LEU A 1 403 ? -38.930 38.629 -29.857 1.00 28.22 ? 404 LEU A O 1 ATOM 3148 C CB . LEU A 1 403 ? -40.412 36.895 -32.225 1.00 24.59 ? 404 LEU A CB 1 ATOM 3149 C CG . LEU A 1 403 ? -40.195 35.902 -31.047 1.00 28.11 ? 404 LEU A CG 1 ATOM 3150 C CD1 . LEU A 1 403 ? -41.161 34.744 -31.100 1.00 29.16 ? 404 LEU A CD1 1 ATOM 3151 C CD2 . LEU A 1 403 ? -38.777 35.359 -30.952 1.00 26.92 ? 404 LEU A CD2 1 ATOM 3152 N N . MET A 1 404 ? -37.885 38.884 -31.900 1.00 26.70 ? 405 MET A N 1 ATOM 3153 C CA . MET A 1 404 ? -36.622 39.085 -31.267 1.00 27.27 ? 405 MET A CA 1 ATOM 3154 C C . MET A 1 404 ? -36.692 40.410 -30.495 1.00 27.43 ? 405 MET A C 1 ATOM 3155 O O . MET A 1 404 ? -35.988 40.577 -29.503 1.00 20.29 ? 405 MET A O 1 ATOM 3156 C CB . MET A 1 404 ? -35.442 39.082 -32.230 1.00 27.48 ? 405 MET A CB 1 ATOM 3157 C CG . MET A 1 404 ? -35.114 37.724 -32.766 1.00 28.25 ? 405 MET A CG 1 ATOM 3158 S SD . MET A 1 404 ? -34.906 36.463 -31.455 1.00 30.57 ? 405 MET A SD 1 ATOM 3159 C CE . MET A 1 404 ? -33.537 37.308 -30.608 1.00 24.52 ? 405 MET A CE 1 ATOM 3160 N N . HIS A 1 405 ? -37.518 41.352 -30.959 1.00 27.05 ? 406 HIS A N 1 ATOM 3161 C CA . HIS A 1 405 ? -37.633 42.659 -30.281 1.00 28.20 ? 406 HIS A CA 1 ATOM 3162 C C . HIS A 1 405 ? -38.434 42.504 -28.973 1.00 28.84 ? 406 HIS A C 1 ATOM 3163 O O . HIS A 1 405 ? -38.103 43.107 -27.945 1.00 30.87 ? 406 HIS A O 1 ATOM 3164 C CB . HIS A 1 405 ? -38.330 43.660 -31.149 1.00 26.50 ? 406 HIS A CB 1 ATOM 3165 C CG . HIS A 1 405 ? -38.546 44.991 -30.506 1.00 27.72 ? 406 HIS A CG 1 ATOM 3166 N ND1 . HIS A 1 405 ? -37.516 45.886 -30.295 1.00 28.79 ? 406 HIS A ND1 1 ATOM 3167 C CD2 . HIS A 1 405 ? -39.680 45.638 -30.156 1.00 29.00 ? 406 HIS A CD2 1 ATOM 3168 C CE1 . HIS A 1 405 ? -37.997 46.997 -29.770 1.00 27.04 ? 406 HIS A CE1 1 ATOM 3169 N NE2 . HIS A 1 405 ? -39.310 46.892 -29.711 1.00 31.16 ? 406 HIS A NE2 1 ATOM 3170 N N . PHE A 1 406 ? -39.489 41.730 -29.048 1.00 27.43 ? 407 PHE A N 1 ATOM 3171 C CA . PHE A 1 406 ? -40.277 41.371 -27.900 1.00 29.34 ? 407 PHE A CA 1 ATOM 3172 C C . PHE A 1 406 ? -39.389 40.681 -26.853 1.00 32.14 ? 407 PHE A C 1 ATOM 3173 O O . PHE A 1 406 ? -39.471 41.014 -25.684 1.00 29.86 ? 407 PHE A O 1 ATOM 3174 C CB . PHE A 1 406 ? -41.426 40.433 -28.277 1.00 29.65 ? 407 PHE A CB 1 ATOM 3175 C CG . PHE A 1 406 ? -42.201 39.951 -27.095 1.00 27.89 ? 407 PHE A CG 1 ATOM 3176 C CD1 . PHE A 1 406 ? -43.061 40.805 -26.434 1.00 29.15 ? 407 PHE A CD1 1 ATOM 3177 C CD2 . PHE A 1 406 ? -42.061 38.683 -26.645 1.00 27.96 ? 407 PHE A CD2 1 ATOM 3178 C CE1 . PHE A 1 406 ? -43.776 40.392 -25.344 1.00 29.23 ? 407 PHE A CE1 1 ATOM 3179 C CE2 . PHE A 1 406 ? -42.755 38.263 -25.506 1.00 33.39 ? 407 PHE A CE2 1 ATOM 3180 C CZ . PHE A 1 406 ? -43.587 39.134 -24.844 1.00 30.18 ? 407 PHE A CZ 1 ATOM 3181 N N . VAL A 1 407 ? -38.551 39.749 -27.281 1.00 29.47 ? 408 VAL A N 1 ATOM 3182 C CA . VAL A 1 407 ? -37.744 38.972 -26.350 1.00 34.45 ? 408 VAL A CA 1 ATOM 3183 C C . VAL A 1 407 ? -36.770 39.848 -25.615 1.00 34.05 ? 408 VAL A C 1 ATOM 3184 O O . VAL A 1 407 ? -36.510 39.662 -24.439 1.00 36.03 ? 408 VAL A O 1 ATOM 3185 C CB . VAL A 1 407 ? -36.938 37.884 -27.079 1.00 39.19 ? 408 VAL A CB 1 ATOM 3186 C CG1 . VAL A 1 407 ? -35.876 37.299 -26.219 1.00 49.14 ? 408 VAL A CG1 1 ATOM 3187 C CG2 . VAL A 1 407 ? -37.850 36.775 -27.430 1.00 46.58 ? 408 VAL A CG2 1 ATOM 3188 N N . ASN A 1 408 ? -36.189 40.780 -26.330 1.00 37.50 ? 409 ASN A N 1 ATOM 3189 C CA . ASN A 1 408 ? -35.130 41.568 -25.770 1.00 36.76 ? 409 ASN A CA 1 ATOM 3190 C C . ASN A 1 408 ? -35.717 42.546 -24.751 1.00 33.88 ? 409 ASN A C 1 ATOM 3191 O O . ASN A 1 408 ? -35.160 42.721 -23.678 1.00 33.78 ? 409 ASN A O 1 ATOM 3192 C CB . ASN A 1 408 ? -34.241 42.168 -26.884 1.00 35.68 ? 409 ASN A CB 1 ATOM 3193 C CG . ASN A 1 408 ? -33.066 41.215 -27.243 1.00 38.82 ? 409 ASN A CG 1 ATOM 3194 O OD1 . ASN A 1 408 ? -32.151 40.980 -26.414 1.00 47.63 ? 409 ASN A OD1 1 ATOM 3195 N ND2 . ASN A 1 408 ? -33.124 40.598 -28.408 1.00 35.75 ? 409 ASN A ND2 1 ATOM 3196 N N . LYS A 1 409 ? -36.878 43.093 -25.053 1.00 27.02 ? 410 LYS A N 1 ATOM 3197 C CA . LYS A 1 409 ? -37.563 43.960 -24.129 1.00 30.84 ? 410 LYS A CA 1 ATOM 3198 C C . LYS A 1 409 ? -38.131 43.217 -22.900 1.00 30.12 ? 410 LYS A C 1 ATOM 3199 O O . LYS A 1 409 ? -38.126 43.776 -21.816 1.00 29.73 ? 410 LYS A O 1 ATOM 3200 C CB . LYS A 1 409 ? -38.764 44.589 -24.798 1.00 32.67 ? 410 LYS A CB 1 ATOM 3201 C CG . LYS A 1 409 ? -38.437 45.527 -25.928 1.00 37.13 ? 410 LYS A CG 1 ATOM 3202 C CD . LYS A 1 409 ? -37.394 46.529 -25.539 1.00 39.33 ? 410 LYS A CD 1 ATOM 3203 C CE . LYS A 1 409 ? -37.450 47.737 -26.449 1.00 38.83 ? 410 LYS A CE 1 ATOM 3204 N NZ . LYS A 1 409 ? -36.772 48.816 -25.713 1.00 42.02 ? 410 LYS A NZ 1 ATOM 3205 N N . TYR A 1 410 ? -38.668 42.014 -23.104 1.00 27.80 ? 411 TYR A N 1 ATOM 3206 C CA . TYR A 1 410 ? -39.352 41.279 -22.068 1.00 30.71 ? 411 TYR A CA 1 ATOM 3207 C C . TYR A 1 410 ? -38.293 40.849 -21.061 1.00 32.86 ? 411 TYR A C 1 ATOM 3208 O O . TYR A 1 410 ? -38.500 40.944 -19.857 1.00 33.05 ? 411 TYR A O 1 ATOM 3209 C CB . TYR A 1 410 ? -40.101 40.020 -22.572 1.00 29.56 ? 411 TYR A CB 1 ATOM 3210 C CG . TYR A 1 410 ? -40.890 39.367 -21.455 1.00 23.15 ? 411 TYR A CG 1 ATOM 3211 C CD1 . TYR A 1 410 ? -42.129 39.814 -21.148 1.00 23.90 ? 411 TYR A CD1 1 ATOM 3212 C CD2 . TYR A 1 410 ? -40.350 38.310 -20.696 1.00 20.98 ? 411 TYR A CD2 1 ATOM 3213 C CE1 . TYR A 1 410 ? -42.868 39.279 -20.125 1.00 24.33 ? 411 TYR A CE1 1 ATOM 3214 C CE2 . TYR A 1 410 ? -41.042 37.771 -19.636 1.00 20.57 ? 411 TYR A CE2 1 ATOM 3215 C CZ . TYR A 1 410 ? -42.298 38.291 -19.331 1.00 25.30 ? 411 TYR A CZ 1 ATOM 3216 O OH . TYR A 1 410 ? -43.088 37.767 -18.361 1.00 24.66 ? 411 TYR A OH 1 ATOM 3217 N N . THR A 1 411 ? -37.177 40.389 -21.582 1.00 31.78 ? 412 THR A N 1 ATOM 3218 C CA . THR A 1 411 ? -36.131 39.798 -20.776 1.00 30.60 ? 412 THR A CA 1 ATOM 3219 C C . THR A 1 411 ? -35.521 40.787 -19.795 1.00 33.28 ? 412 THR A C 1 ATOM 3220 O O . THR A 1 411 ? -35.042 40.366 -18.796 1.00 33.32 ? 412 THR A O 1 ATOM 3221 C CB . THR A 1 411 ? -35.091 39.099 -21.677 1.00 27.22 ? 412 THR A CB 1 ATOM 3222 O OG1 . THR A 1 411 ? -35.681 37.905 -22.240 1.00 32.71 ? 412 THR A OG1 1 ATOM 3223 C CG2 . THR A 1 411 ? -33.873 38.657 -20.948 1.00 26.62 ? 412 THR A CG2 1 ATOM 3224 N N . LYS A 1 412 ? -35.595 42.086 -20.048 1.00 34.01 ? 413 LYS A N 1 ATOM 3225 C CA . LYS A 1 412 ? -35.140 43.027 -19.066 1.00 40.11 ? 413 LYS A CA 1 ATOM 3226 C C . LYS A 1 412 ? -35.920 42.946 -17.753 1.00 42.77 ? 413 LYS A C 1 ATOM 3227 O O . LYS A 1 412 ? -35.311 43.186 -16.740 1.00 38.76 ? 413 LYS A O 1 ATOM 3228 C CB . LYS A 1 412 ? -35.216 44.484 -19.554 1.00 45.78 ? 413 LYS A CB 1 ATOM 3229 C CG . LYS A 1 412 ? -34.139 44.816 -20.577 1.00 62.15 ? 413 LYS A CG 1 ATOM 3230 C CD . LYS A 1 412 ? -34.294 46.232 -21.125 1.00 69.05 ? 413 LYS A CD 1 ATOM 3231 C CE . LYS A 1 412 ? -33.863 46.314 -22.589 1.00 73.80 ? 413 LYS A CE 1 ATOM 3232 N NZ . LYS A 1 412 ? -34.266 47.621 -23.206 1.00 74.55 ? 413 LYS A NZ 1 ATOM 3233 N N . PHE A 1 413 ? -37.249 42.714 -17.783 1.00 34.66 ? 414 PHE A N 1 ATOM 3234 C CA . PHE A 1 413 ? -38.093 42.729 -16.592 1.00 31.23 ? 414 PHE A CA 1 ATOM 3235 C C . PHE A 1 413 ? -38.625 41.362 -16.148 1.00 30.66 ? 414 PHE A C 1 ATOM 3236 O O . PHE A 1 413 ? -39.117 41.234 -15.043 1.00 32.80 ? 414 PHE A O 1 ATOM 3237 C CB . PHE A 1 413 ? -39.306 43.602 -16.815 1.00 32.47 ? 414 PHE A CB 1 ATOM 3238 C CG . PHE A 1 413 ? -38.981 45.032 -16.992 1.00 35.75 ? 414 PHE A CG 1 ATOM 3239 C CD1 . PHE A 1 413 ? -38.865 45.873 -15.893 1.00 38.70 ? 414 PHE A CD1 1 ATOM 3240 C CD2 . PHE A 1 413 ? -38.746 45.539 -18.244 1.00 34.74 ? 414 PHE A CD2 1 ATOM 3241 C CE1 . PHE A 1 413 ? -38.570 47.200 -16.073 1.00 38.03 ? 414 PHE A CE1 1 ATOM 3242 C CE2 . PHE A 1 413 ? -38.458 46.861 -18.442 1.00 36.03 ? 414 PHE A CE2 1 ATOM 3243 C CZ . PHE A 1 413 ? -38.358 47.689 -17.364 1.00 42.27 ? 414 PHE A CZ 1 ATOM 3244 N N . GLY A 1 414 ? -38.477 40.343 -16.976 1.00 30.26 ? 415 GLY A N 1 ATOM 3245 C CA . GLY A 1 414 ? -39.128 39.065 -16.754 1.00 28.43 ? 415 GLY A CA 1 ATOM 3246 C C . GLY A 1 414 ? -38.277 38.187 -15.875 1.00 27.27 ? 415 GLY A C 1 ATOM 3247 O O . GLY A 1 414 ? -37.182 38.570 -15.435 1.00 27.84 ? 415 GLY A O 1 ATOM 3248 N N . ASN A 1 415 ? -38.794 37.013 -15.631 1.00 28.15 ? 416 ASN A N 1 ATOM 3249 C CA . ASN A 1 415 ? -38.219 36.091 -14.699 1.00 35.21 ? 416 ASN A CA 1 ATOM 3250 C C . ASN A 1 415 ? -37.656 34.813 -15.309 1.00 36.00 ? 416 ASN A C 1 ATOM 3251 O O . ASN A 1 415 ? -37.427 33.841 -14.592 1.00 34.35 ? 416 ASN A O 1 ATOM 3252 C CB . ASN A 1 415 ? -39.277 35.765 -13.613 1.00 41.47 ? 416 ASN A CB 1 ATOM 3253 C CG . ASN A 1 415 ? -38.708 34.951 -12.447 1.00 41.59 ? 416 ASN A CG 1 ATOM 3254 O OD1 . ASN A 1 415 ? -39.233 33.854 -12.157 1.00 41.67 ? 416 ASN A OD1 1 ATOM 3255 N ND2 . ASN A 1 415 ? -37.618 35.440 -11.807 1.00 39.43 ? 416 ASN A ND2 1 ATOM 3256 N N . GLY A 1 416 ? -37.359 34.847 -16.612 1.00 38.79 ? 417 GLY A N 1 ATOM 3257 C CA . GLY A 1 416 ? -36.714 33.732 -17.294 1.00 35.93 ? 417 GLY A CA 1 ATOM 3258 C C . GLY A 1 416 ? -37.279 33.501 -18.683 1.00 36.49 ? 417 GLY A C 1 ATOM 3259 O O . GLY A 1 416 ? -38.483 33.355 -18.843 1.00 28.80 ? 417 GLY A O 1 ATOM 3260 N N . THR A 1 417 ? -36.378 33.437 -19.665 1.00 34.67 ? 418 THR A N 1 ATOM 3261 C CA . THR A 1 417 ? -36.720 33.401 -21.056 1.00 33.77 ? 418 THR A CA 1 ATOM 3262 C C . THR A 1 417 ? -36.004 32.231 -21.649 1.00 31.74 ? 418 THR A C 1 ATOM 3263 O O . THR A 1 417 ? -34.792 32.081 -21.395 1.00 28.83 ? 418 THR A O 1 ATOM 3264 C CB . THR A 1 417 ? -36.292 34.725 -21.771 1.00 37.59 ? 418 THR A CB 1 ATOM 3265 O OG1 . THR A 1 417 ? -36.998 35.856 -21.195 1.00 29.23 ? 418 THR A OG1 1 ATOM 3266 C CG2 . THR A 1 417 ? -36.594 34.635 -23.297 1.00 34.48 ? 418 THR A CG2 1 ATOM 3267 N N . TYR A 1 418 ? -36.752 31.349 -22.351 1.00 28.70 ? 419 TYR A N 1 ATOM 3268 C CA . TYR A 1 418 ? -36.140 30.249 -23.114 1.00 29.72 ? 419 TYR A CA 1 ATOM 3269 C C . TYR A 1 418 ? -36.469 30.381 -24.614 1.00 32.37 ? 419 TYR A C 1 ATOM 3270 O O . TYR A 1 418 ? -37.639 30.402 -24.966 1.00 29.33 ? 419 TYR A O 1 ATOM 3271 C CB . TYR A 1 418 ? -36.548 28.866 -22.580 1.00 33.02 ? 419 TYR A CB 1 ATOM 3272 C CG . TYR A 1 418 ? -36.078 28.625 -21.172 1.00 35.95 ? 419 TYR A CG 1 ATOM 3273 C CD1 . TYR A 1 418 ? -36.844 29.051 -20.095 1.00 34.57 ? 419 TYR A CD1 1 ATOM 3274 C CD2 . TYR A 1 418 ? -34.856 28.057 -20.920 1.00 37.95 ? 419 TYR A CD2 1 ATOM 3275 C CE1 . TYR A 1 418 ? -36.418 28.890 -18.808 1.00 38.35 ? 419 TYR A CE1 1 ATOM 3276 C CE2 . TYR A 1 418 ? -34.408 27.911 -19.620 1.00 38.91 ? 419 TYR A CE2 1 ATOM 3277 C CZ . TYR A 1 418 ? -35.218 28.309 -18.568 1.00 36.48 ? 419 TYR A CZ 1 ATOM 3278 O OH . TYR A 1 418 ? -34.815 28.190 -17.270 1.00 31.37 ? 419 TYR A OH 1 ATOM 3279 N N . LEU A 1 419 ? -35.442 30.499 -25.468 1.00 31.26 ? 420 LEU A N 1 ATOM 3280 C CA . LEU A 1 419 ? -35.621 30.782 -26.897 1.00 28.01 ? 420 LEU A CA 1 ATOM 3281 C C . LEU A 1 419 ? -35.207 29.614 -27.803 1.00 29.71 ? 420 LEU A C 1 ATOM 3282 O O . LEU A 1 419 ? -34.116 29.029 -27.661 1.00 26.33 ? 420 LEU A O 1 ATOM 3283 C CB . LEU A 1 419 ? -34.844 32.038 -27.306 1.00 28.39 ? 420 LEU A CB 1 ATOM 3284 C CG . LEU A 1 419 ? -34.941 32.535 -28.777 1.00 29.46 ? 420 LEU A CG 1 ATOM 3285 C CD1 . LEU A 1 419 ? -36.397 32.813 -29.181 1.00 28.63 ? 420 LEU A CD1 1 ATOM 3286 C CD2 . LEU A 1 419 ? -34.073 33.779 -29.018 1.00 27.91 ? 420 LEU A CD2 1 ATOM 3287 N N . TYR A 1 420 ? -36.084 29.275 -28.743 1.00 26.26 ? 421 TYR A N 1 ATOM 3288 C CA . TYR A 1 420 ? -35.761 28.246 -29.724 1.00 28.91 ? 421 TYR A CA 1 ATOM 3289 C C . TYR A 1 420 ? -35.863 28.671 -31.224 1.00 28.45 ? 421 TYR A C 1 ATOM 3290 O O . TYR A 1 420 ? -36.592 29.610 -31.584 1.00 28.00 ? 421 TYR A O 1 ATOM 3291 C CB . TYR A 1 420 ? -36.647 27.023 -29.522 1.00 26.51 ? 421 TYR A CB 1 ATOM 3292 C CG . TYR A 1 420 ? -38.065 27.223 -29.978 1.00 28.96 ? 421 TYR A CG 1 ATOM 3293 C CD1 . TYR A 1 420 ? -38.440 27.062 -31.324 1.00 30.09 ? 421 TYR A CD1 1 ATOM 3294 C CD2 . TYR A 1 420 ? -39.060 27.526 -29.069 1.00 29.71 ? 421 TYR A CD2 1 ATOM 3295 C CE1 . TYR A 1 420 ? -39.786 27.211 -31.728 1.00 26.79 ? 421 TYR A CE1 1 ATOM 3296 C CE2 . TYR A 1 420 ? -40.362 27.687 -29.461 1.00 28.69 ? 421 TYR A CE2 1 ATOM 3297 C CZ . TYR A 1 420 ? -40.715 27.548 -30.793 1.00 28.14 ? 421 TYR A CZ 1 ATOM 3298 O OH . TYR A 1 420 ? -42.019 27.746 -31.103 1.00 27.42 ? 421 TYR A OH 1 ATOM 3299 N N . PHE A 1 421 ? -35.223 27.862 -32.073 1.00 25.67 ? 422 PHE A N 1 ATOM 3300 C CA . PHE A 1 421 ? -35.261 28.010 -33.496 1.00 25.51 ? 422 PHE A CA 1 ATOM 3301 C C . PHE A 1 421 ? -35.541 26.635 -34.015 1.00 26.26 ? 422 PHE A C 1 ATOM 3302 O O . PHE A 1 421 ? -34.676 25.719 -33.926 1.00 28.44 ? 422 PHE A O 1 ATOM 3303 C CB . PHE A 1 421 ? -33.919 28.543 -33.992 1.00 29.80 ? 422 PHE A CB 1 ATOM 3304 C CG . PHE A 1 421 ? -33.871 28.898 -35.492 1.00 31.03 ? 422 PHE A CG 1 ATOM 3305 C CD1 . PHE A 1 421 ? -34.484 30.055 -35.975 1.00 32.32 ? 422 PHE A CD1 1 ATOM 3306 C CD2 . PHE A 1 421 ? -33.138 28.122 -36.387 1.00 28.54 ? 422 PHE A CD2 1 ATOM 3307 C CE1 . PHE A 1 421 ? -34.449 30.382 -37.340 1.00 31.65 ? 422 PHE A CE1 1 ATOM 3308 C CE2 . PHE A 1 421 ? -33.060 28.466 -37.736 1.00 31.94 ? 422 PHE A CE2 1 ATOM 3309 C CZ . PHE A 1 421 ? -33.716 29.591 -38.213 1.00 31.24 ? 422 PHE A CZ 1 ATOM 3310 N N . PHE A 1 422 ? -36.759 26.440 -34.488 1.00 24.07 ? 423 PHE A N 1 ATOM 3311 C CA . PHE A 1 422 ? -37.161 25.143 -34.975 1.00 27.19 ? 423 PHE A CA 1 ATOM 3312 C C . PHE A 1 422 ? -36.847 25.071 -36.474 1.00 32.94 ? 423 PHE A C 1 ATOM 3313 O O . PHE A 1 422 ? -37.394 25.889 -37.297 1.00 36.03 ? 423 PHE A O 1 ATOM 3314 C CB . PHE A 1 422 ? -38.638 24.971 -34.718 1.00 27.11 ? 423 PHE A CB 1 ATOM 3315 C CG . PHE A 1 422 ? -39.189 23.725 -35.260 1.00 30.48 ? 423 PHE A CG 1 ATOM 3316 C CD1 . PHE A 1 422 ? -39.163 22.555 -34.520 1.00 31.11 ? 423 PHE A CD1 1 ATOM 3317 C CD2 . PHE A 1 422 ? -39.773 23.708 -36.542 1.00 30.57 ? 423 PHE A CD2 1 ATOM 3318 C CE1 . PHE A 1 422 ? -39.700 21.374 -35.044 1.00 30.30 ? 423 PHE A CE1 1 ATOM 3319 C CE2 . PHE A 1 422 ? -40.319 22.543 -37.051 1.00 28.63 ? 423 PHE A CE2 1 ATOM 3320 C CZ . PHE A 1 422 ? -40.268 21.374 -36.311 1.00 29.04 ? 423 PHE A CZ 1 ATOM 3321 N N . ASN A 1 423 ? -35.969 24.134 -36.848 1.00 32.80 ? 424 ASN A N 1 ATOM 3322 C CA . ASN A 1 423 ? -35.563 24.035 -38.235 1.00 34.35 ? 424 ASN A CA 1 ATOM 3323 C C . ASN A 1 423 ? -35.491 22.614 -38.787 1.00 35.89 ? 424 ASN A C 1 ATOM 3324 O O . ASN A 1 423 ? -34.642 22.331 -39.609 1.00 40.96 ? 424 ASN A O 1 ATOM 3325 C CB . ASN A 1 423 ? -34.259 24.760 -38.432 1.00 33.00 ? 424 ASN A CB 1 ATOM 3326 C CG . ASN A 1 423 ? -33.113 24.120 -37.676 1.00 36.01 ? 424 ASN A CG 1 ATOM 3327 O OD1 . ASN A 1 423 ? -33.303 23.251 -36.831 1.00 34.27 ? 424 ASN A OD1 1 ATOM 3328 N ND2 . ASN A 1 423 ? -31.915 24.578 -37.962 1.00 36.25 ? 424 ASN A ND2 1 ATOM 3329 N N . HIS A 1 424 ? -36.405 21.768 -38.375 1.00 31.78 ? 425 HIS A N 1 ATOM 3330 C CA . HIS A 1 424 ? -36.532 20.447 -38.938 1.00 37.79 ? 425 HIS A CA 1 ATOM 3331 C C . HIS A 1 424 ? -37.688 20.398 -39.939 1.00 35.61 ? 425 HIS A C 1 ATOM 3332 O O . HIS A 1 424 ? -38.832 20.643 -39.545 1.00 40.51 ? 425 HIS A O 1 ATOM 3333 C CB . HIS A 1 424 ? -36.850 19.402 -37.836 1.00 35.59 ? 425 HIS A CB 1 ATOM 3334 C CG . HIS A 1 424 ? -37.107 18.021 -38.376 1.00 33.08 ? 425 HIS A CG 1 ATOM 3335 N ND1 . HIS A 1 424 ? -36.110 17.239 -38.931 1.00 35.23 ? 425 HIS A ND1 1 ATOM 3336 C CD2 . HIS A 1 424 ? -38.253 17.330 -38.542 1.00 32.50 ? 425 HIS A CD2 1 ATOM 3337 C CE1 . HIS A 1 424 ? -36.628 16.106 -39.378 1.00 31.73 ? 425 HIS A CE1 1 ATOM 3338 N NE2 . HIS A 1 424 ? -37.929 16.141 -39.166 1.00 32.13 ? 425 HIS A NE2 1 ATOM 3339 N N . ARG A 1 425 ? -37.447 20.012 -41.187 1.00 40.05 ? 426 ARG A N 1 ATOM 3340 C CA . ARG A 1 425 ? -38.580 19.861 -42.111 1.00 48.55 ? 426 ARG A CA 1 ATOM 3341 C C . ARG A 1 425 ? -39.030 18.423 -42.010 1.00 46.21 ? 426 ARG A C 1 ATOM 3342 O O . ARG A 1 425 ? -38.219 17.514 -42.085 1.00 42.01 ? 426 ARG A O 1 ATOM 3343 C CB . ARG A 1 425 ? -38.332 20.391 -43.561 1.00 59.09 ? 426 ARG A CB 1 ATOM 3344 C CG . ARG A 1 425 ? -37.995 19.445 -44.725 1.00 68.22 ? 426 ARG A CG 1 ATOM 3345 C CD . ARG A 1 425 ? -39.109 19.254 -45.818 1.00 64.23 ? 426 ARG A CD 1 ATOM 3346 N NE . ARG A 1 425 ? -39.716 20.480 -46.303 1.00 62.27 ? 426 ARG A NE 1 ATOM 3347 C CZ . ARG A 1 425 ? -40.591 20.640 -47.324 1.00 52.38 ? 426 ARG A CZ 1 ATOM 3348 N NH1 . ARG A 1 425 ? -41.020 19.646 -48.096 1.00 47.01 ? 426 ARG A NH1 1 ATOM 3349 N NH2 . ARG A 1 425 ? -41.054 21.885 -47.555 1.00 40.68 ? 426 ARG A NH2 1 ATOM 3350 N N . ALA A 1 426 ? -40.331 18.272 -41.746 1.00 44.73 ? 427 ALA A N 1 ATOM 3351 C CA . ALA A 1 426 ? -40.930 17.005 -41.479 1.00 47.38 ? 427 ALA A CA 1 ATOM 3352 C C . ALA A 1 426 ? -40.800 16.189 -42.754 1.00 48.71 ? 427 ALA A C 1 ATOM 3353 O O . ALA A 1 426 ? -41.001 16.723 -43.856 1.00 49.48 ? 427 ALA A O 1 ATOM 3354 C CB . ALA A 1 426 ? -42.395 17.162 -41.068 1.00 42.90 ? 427 ALA A CB 1 ATOM 3355 N N . SER A 1 427 ? -40.465 14.910 -42.580 1.00 49.01 ? 428 SER A N 1 ATOM 3356 C CA . SER A 1 427 ? -40.152 13.951 -43.672 1.00 50.25 ? 428 SER A CA 1 ATOM 3357 C C . SER A 1 427 ? -41.377 13.685 -44.544 1.00 47.79 ? 428 SER A C 1 ATOM 3358 O O . SER A 1 427 ? -41.209 13.334 -45.670 1.00 46.01 ? 428 SER A O 1 ATOM 3359 C CB . SER A 1 427 ? -39.657 12.597 -43.076 1.00 49.75 ? 428 SER A CB 1 ATOM 3360 O OG . SER A 1 427 ? -40.699 12.035 -42.232 1.00 47.75 ? 428 SER A OG 1 ATOM 3361 N N . ASN A 1 428 ? -42.590 13.847 -44.006 1.00 45.21 ? 429 ASN A N 1 ATOM 3362 C CA . ASN A 1 428 ? -43.832 13.593 -44.745 1.00 42.41 ? 429 ASN A CA 1 ATOM 3363 C C . ASN A 1 428 ? -44.583 14.893 -45.178 1.00 44.65 ? 429 ASN A C 1 ATOM 3364 O O . ASN A 1 428 ? -45.810 14.889 -45.385 1.00 41.11 ? 429 ASN A O 1 ATOM 3365 C CB . ASN A 1 428 ? -44.771 12.745 -43.868 1.00 42.59 ? 429 ASN A CB 1 ATOM 3366 C CG . ASN A 1 428 ? -45.093 13.419 -42.485 1.00 48.04 ? 429 ASN A CG 1 ATOM 3367 O OD1 . ASN A 1 428 ? -44.578 14.509 -42.149 1.00 39.36 ? 429 ASN A OD1 1 ATOM 3368 N ND2 . ASN A 1 428 ? -45.927 12.742 -41.671 1.00 42.83 ? 429 ASN A ND2 1 ATOM 3369 N N . LEU A 1 429 ? -43.886 16.018 -45.269 1.00 43.62 ? 430 LEU A N 1 ATOM 3370 C CA . LEU A 1 429 ? -44.578 17.274 -45.634 1.00 45.08 ? 430 LEU A CA 1 ATOM 3371 C C . LEU A 1 429 ? -45.083 17.168 -47.106 1.00 44.60 ? 430 LEU A C 1 ATOM 3372 O O . LEU A 1 429 ? -44.359 16.773 -48.018 1.00 40.40 ? 430 LEU A O 1 ATOM 3373 C CB . LEU A 1 429 ? -43.659 18.510 -45.474 1.00 51.79 ? 430 LEU A CB 1 ATOM 3374 C CG . LEU A 1 429 ? -44.210 19.762 -44.768 1.00 54.59 ? 430 LEU A CG 1 ATOM 3375 C CD1 . LEU A 1 429 ? -44.845 19.409 -43.467 1.00 61.91 ? 430 LEU A CD1 1 ATOM 3376 C CD2 . LEU A 1 429 ? -43.079 20.708 -44.452 1.00 60.32 ? 430 LEU A CD2 1 ATOM 3377 N N . VAL A 1 430 ? -46.349 17.478 -47.289 1.00 42.65 ? 431 VAL A N 1 ATOM 3378 C CA . VAL A 1 430 ? -46.980 17.392 -48.567 1.00 41.04 ? 431 VAL A CA 1 ATOM 3379 C C . VAL A 1 430 ? -46.655 18.640 -49.387 1.00 38.95 ? 431 VAL A C 1 ATOM 3380 O O . VAL A 1 430 ? -46.847 18.629 -50.582 1.00 37.88 ? 431 VAL A O 1 ATOM 3381 C CB . VAL A 1 430 ? -48.498 17.223 -48.380 1.00 44.13 ? 431 VAL A CB 1 ATOM 3382 C CG1 . VAL A 1 430 ? -48.778 15.837 -47.797 1.00 42.30 ? 431 VAL A CG1 1 ATOM 3383 C CG2 . VAL A 1 430 ? -49.060 18.326 -47.432 1.00 41.76 ? 431 VAL A CG2 1 ATOM 3384 N N . TRP A 1 431 ? -46.206 19.715 -48.741 1.00 36.52 ? 432 TRP A N 1 ATOM 3385 C CA . TRP A 1 431 ? -45.910 20.991 -49.428 1.00 31.77 ? 432 TRP A CA 1 ATOM 3386 C C . TRP A 1 431 ? -44.578 20.831 -50.098 1.00 27.50 ? 432 TRP A C 1 ATOM 3387 O O . TRP A 1 431 ? -43.802 20.017 -49.689 1.00 33.44 ? 432 TRP A O 1 ATOM 3388 C CB . TRP A 1 431 ? -45.859 22.190 -48.421 1.00 30.44 ? 432 TRP A CB 1 ATOM 3389 C CG . TRP A 1 431 ? -47.138 22.585 -47.837 1.00 28.96 ? 432 TRP A CG 1 ATOM 3390 C CD1 . TRP A 1 431 ? -47.596 22.236 -46.602 1.00 28.51 ? 432 TRP A CD1 1 ATOM 3391 C CD2 . TRP A 1 431 ? -48.192 23.324 -48.454 1.00 29.61 ? 432 TRP A CD2 1 ATOM 3392 N NE1 . TRP A 1 431 ? -48.849 22.701 -46.413 1.00 29.98 ? 432 TRP A NE1 1 ATOM 3393 C CE2 . TRP A 1 431 ? -49.241 23.412 -47.509 1.00 30.96 ? 432 TRP A CE2 1 ATOM 3394 C CE3 . TRP A 1 431 ? -48.357 23.922 -49.690 1.00 32.36 ? 432 TRP A CE3 1 ATOM 3395 C CZ2 . TRP A 1 431 ? -50.452 24.068 -47.771 1.00 33.84 ? 432 TRP A CZ2 1 ATOM 3396 C CZ3 . TRP A 1 431 ? -49.569 24.635 -49.953 1.00 36.07 ? 432 TRP A CZ3 1 ATOM 3397 C CH2 . TRP A 1 431 ? -50.591 24.691 -48.989 1.00 37.91 ? 432 TRP A CH2 1 ATOM 3398 N N . PRO A 1 432 ? -44.284 21.614 -51.129 1.00 28.96 ? 433 PRO A N 1 ATOM 3399 C CA . PRO A 1 432 ? -43.015 21.411 -51.846 1.00 26.89 ? 433 PRO A CA 1 ATOM 3400 C C . PRO A 1 432 ? -41.785 21.811 -51.019 1.00 29.50 ? 433 PRO A C 1 ATOM 3401 O O . PRO A 1 432 ? -41.866 22.636 -50.105 1.00 30.55 ? 433 PRO A O 1 ATOM 3402 C CB . PRO A 1 432 ? -43.173 22.373 -53.030 1.00 28.02 ? 433 PRO A CB 1 ATOM 3403 C CG . PRO A 1 432 ? -44.110 23.503 -52.517 1.00 25.98 ? 433 PRO A CG 1 ATOM 3404 C CD . PRO A 1 432 ? -45.088 22.714 -51.730 1.00 28.00 ? 433 PRO A CD 1 ATOM 3405 N N . GLU A 1 433 ? -40.630 21.346 -51.436 1.00 32.91 ? 434 GLU A N 1 ATOM 3406 C CA . GLU A 1 433 ? -39.378 21.576 -50.765 1.00 35.13 ? 434 GLU A CA 1 ATOM 3407 C C . GLU A 1 433 ? -39.019 23.034 -50.624 1.00 32.11 ? 434 GLU A C 1 ATOM 3408 O O . GLU A 1 433 ? -38.323 23.410 -49.693 1.00 28.32 ? 434 GLU A O 1 ATOM 3409 C CB . GLU A 1 433 ? -38.237 20.934 -51.548 1.00 42.07 ? 434 GLU A CB 1 ATOM 3410 C CG . GLU A 1 433 ? -38.279 19.412 -51.587 1.00 59.17 ? 434 GLU A CG 1 ATOM 3411 C CD . GLU A 1 433 ? -38.046 18.765 -50.221 1.00 74.26 ? 434 GLU A CD 1 ATOM 3412 O OE1 . GLU A 1 433 ? -37.096 19.186 -49.507 1.00 82.45 ? 434 GLU A OE1 1 ATOM 3413 O OE2 . GLU A 1 433 ? -38.818 17.835 -49.854 1.00 77.16 ? 434 GLU A OE2 1 ATOM 3414 N N . TRP A 1 434 ? -39.339 23.847 -51.624 1.00 31.98 ? 435 TRP A N 1 ATOM 3415 C CA . TRP A 1 434 ? -38.837 25.209 -51.577 1.00 30.24 ? 435 TRP A CA 1 ATOM 3416 C C . TRP A 1 434 ? -39.377 25.982 -50.326 1.00 27.83 ? 435 TRP A C 1 ATOM 3417 O O . TRP A 1 434 ? -38.767 26.902 -49.895 1.00 25.50 ? 435 TRP A O 1 ATOM 3418 C CB . TRP A 1 434 ? -39.093 25.967 -52.874 1.00 27.24 ? 435 TRP A CB 1 ATOM 3419 C CG . TRP A 1 434 ? -40.524 26.300 -53.164 1.00 30.37 ? 435 TRP A CG 1 ATOM 3420 C CD1 . TRP A 1 434 ? -41.355 25.597 -53.966 1.00 32.06 ? 435 TRP A CD1 1 ATOM 3421 C CD2 . TRP A 1 434 ? -41.290 27.429 -52.698 1.00 26.61 ? 435 TRP A CD2 1 ATOM 3422 N NE1 . TRP A 1 434 ? -42.590 26.197 -54.028 1.00 31.60 ? 435 TRP A NE1 1 ATOM 3423 C CE2 . TRP A 1 434 ? -42.580 27.314 -53.253 1.00 28.24 ? 435 TRP A CE2 1 ATOM 3424 C CE3 . TRP A 1 434 ? -41.031 28.479 -51.832 1.00 30.01 ? 435 TRP A CE3 1 ATOM 3425 C CZ2 . TRP A 1 434 ? -43.599 28.206 -52.993 1.00 31.19 ? 435 TRP A CZ2 1 ATOM 3426 C CZ3 . TRP A 1 434 ? -42.073 29.420 -51.575 1.00 31.00 ? 435 TRP A CZ3 1 ATOM 3427 C CH2 . TRP A 1 434 ? -43.334 29.257 -52.147 1.00 33.73 ? 435 TRP A CH2 1 ATOM 3428 N N . MET A 1 435 ? -40.540 25.589 -49.802 1.00 28.57 ? 436 MET A N 1 ATOM 3429 C CA . MET A 1 435 ? -41.185 26.265 -48.674 1.00 27.08 ? 436 MET A CA 1 ATOM 3430 C C . MET A 1 435 ? -40.450 26.026 -47.342 1.00 31.50 ? 436 MET A C 1 ATOM 3431 O O . MET A 1 435 ? -40.684 26.762 -46.378 1.00 31.80 ? 436 MET A O 1 ATOM 3432 C CB . MET A 1 435 ? -42.664 25.861 -48.587 1.00 26.61 ? 436 MET A CB 1 ATOM 3433 C CG . MET A 1 435 ? -43.453 26.340 -49.799 1.00 26.37 ? 436 MET A CG 1 ATOM 3434 S SD . MET A 1 435 ? -45.128 25.750 -49.904 1.00 28.70 ? 436 MET A SD 1 ATOM 3435 C CE . MET A 1 435 ? -45.934 26.925 -48.797 1.00 30.17 ? 436 MET A CE 1 ATOM 3436 N N . GLY A 1 436 ? -39.530 25.056 -47.330 1.00 30.38 ? 437 GLY A N 1 ATOM 3437 C CA . GLY A 1 436 ? -38.680 24.748 -46.194 1.00 30.10 ? 437 GLY A CA 1 ATOM 3438 C C . GLY A 1 436 ? -39.428 24.270 -44.939 1.00 29.58 ? 437 GLY A C 1 ATOM 3439 O O . GLY A 1 436 ? -40.289 23.407 -44.989 1.00 28.19 ? 437 GLY A O 1 ATOM 3440 N N . VAL A 1 437 ? -39.120 24.902 -43.819 1.00 29.72 ? 438 VAL A N 1 ATOM 3441 C CA . VAL A 1 437 ? -39.745 24.599 -42.531 1.00 28.73 ? 438 VAL A CA 1 ATOM 3442 C C . VAL A 1 437 ? -40.827 25.689 -42.362 1.00 29.48 ? 438 VAL A C 1 ATOM 3443 O O . VAL A 1 437 ? -40.601 26.823 -41.882 1.00 29.64 ? 438 VAL A O 1 ATOM 3444 C CB . VAL A 1 437 ? -38.702 24.679 -41.438 1.00 30.50 ? 438 VAL A CB 1 ATOM 3445 C CG1 . VAL A 1 437 ? -39.268 24.256 -40.099 1.00 32.63 ? 438 VAL A CG1 1 ATOM 3446 C CG2 . VAL A 1 437 ? -37.492 23.847 -41.809 1.00 32.85 ? 438 VAL A CG2 1 ATOM 3447 N N . ILE A 1 438 ? -42.010 25.304 -42.767 1.00 30.12 ? 439 ILE A N 1 ATOM 3448 C CA . ILE A 1 438 ? -43.138 26.179 -42.961 1.00 31.08 ? 439 ILE A CA 1 ATOM 3449 C C . ILE A 1 438 ? -43.852 26.605 -41.650 1.00 35.46 ? 439 ILE A C 1 ATOM 3450 O O . ILE A 1 438 ? -43.887 25.882 -40.639 1.00 34.49 ? 439 ILE A O 1 ATOM 3451 C CB . ILE A 1 438 ? -44.157 25.445 -43.810 1.00 31.77 ? 439 ILE A CB 1 ATOM 3452 C CG1 . ILE A 1 438 ? -43.490 25.050 -45.133 1.00 36.30 ? 439 ILE A CG1 1 ATOM 3453 C CG2 . ILE A 1 438 ? -45.428 26.262 -44.012 1.00 34.01 ? 439 ILE A CG2 1 ATOM 3454 C CD1 . ILE A 1 438 ? -44.341 24.141 -45.986 1.00 35.21 ? 439 ILE A CD1 1 ATOM 3455 N N . HIS A 1 439 ? -44.404 27.810 -41.721 1.00 31.94 ? 440 HIS A N 1 ATOM 3456 C CA . HIS A 1 439 ? -45.192 28.403 -40.726 1.00 34.13 ? 440 HIS A CA 1 ATOM 3457 C C . HIS A 1 439 ? -46.149 27.328 -40.263 1.00 32.28 ? 440 HIS A C 1 ATOM 3458 O O . HIS A 1 439 ? -46.856 26.752 -41.053 1.00 32.20 ? 440 HIS A O 1 ATOM 3459 C CB . HIS A 1 439 ? -45.921 29.551 -41.384 1.00 37.54 ? 440 HIS A CB 1 ATOM 3460 C CG . HIS A 1 439 ? -46.685 30.427 -40.464 1.00 42.43 ? 440 HIS A CG 1 ATOM 3461 N ND1 . HIS A 1 439 ? -46.065 31.254 -39.529 1.00 48.28 ? 440 HIS A ND1 1 ATOM 3462 C CD2 . HIS A 1 439 ? -48.020 30.666 -40.376 1.00 40.40 ? 440 HIS A CD2 1 ATOM 3463 C CE1 . HIS A 1 439 ? -46.997 31.965 -38.906 1.00 50.98 ? 440 HIS A CE1 1 ATOM 3464 N NE2 . HIS A 1 439 ? -48.188 31.617 -39.393 1.00 49.02 ? 440 HIS A NE2 1 ATOM 3465 N N . GLY A 1 440 ? -46.160 27.037 -38.975 1.00 30.09 ? 441 GLY A N 1 ATOM 3466 C CA . GLY A 1 440 ? -47.166 26.093 -38.460 1.00 31.05 ? 441 GLY A CA 1 ATOM 3467 C C . GLY A 1 440 ? -46.777 24.638 -38.376 1.00 30.09 ? 441 GLY A C 1 ATOM 3468 O O . GLY A 1 440 ? -47.528 23.847 -37.831 1.00 28.28 ? 441 GLY A O 1 ATOM 3469 N N . TYR A 1 441 ? -45.581 24.269 -38.831 1.00 30.99 ? 442 TYR A N 1 ATOM 3470 C CA . TYR A 1 441 ? -45.274 22.838 -38.939 1.00 32.01 ? 442 TYR A CA 1 ATOM 3471 C C . TYR A 1 441 ? -44.451 22.347 -37.755 1.00 35.37 ? 442 TYR A C 1 ATOM 3472 O O . TYR A 1 441 ? -44.022 21.186 -37.707 1.00 38.00 ? 442 TYR A O 1 ATOM 3473 C CB . TYR A 1 441 ? -44.725 22.480 -40.376 1.00 34.25 ? 442 TYR A CB 1 ATOM 3474 C CG . TYR A 1 441 ? -45.935 22.364 -41.326 1.00 33.76 ? 442 TYR A CG 1 ATOM 3475 C CD1 . TYR A 1 441 ? -46.541 23.503 -41.843 1.00 35.87 ? 442 TYR A CD1 1 ATOM 3476 C CD2 . TYR A 1 441 ? -46.596 21.104 -41.550 1.00 37.25 ? 442 TYR A CD2 1 ATOM 3477 C CE1 . TYR A 1 441 ? -47.703 23.421 -42.635 1.00 38.09 ? 442 TYR A CE1 1 ATOM 3478 C CE2 . TYR A 1 441 ? -47.754 21.024 -42.313 1.00 34.07 ? 442 TYR A CE2 1 ATOM 3479 C CZ . TYR A 1 441 ? -48.298 22.191 -42.860 1.00 34.37 ? 442 TYR A CZ 1 ATOM 3480 O OH . TYR A 1 441 ? -49.430 22.157 -43.610 1.00 34.93 ? 442 TYR A OH 1 ATOM 3481 N N . GLU A 1 442 ? -44.286 23.211 -36.753 1.00 27.86 ? 443 GLU A N 1 ATOM 3482 C CA . GLU A 1 442 ? -43.819 22.739 -35.448 1.00 26.46 ? 443 GLU A CA 1 ATOM 3483 C C . GLU A 1 442 ? -45.033 22.267 -34.633 1.00 25.02 ? 443 GLU A C 1 ATOM 3484 O O . GLU A 1 442 ? -44.927 21.461 -33.738 1.00 27.49 ? 443 GLU A O 1 ATOM 3485 C CB . GLU A 1 442 ? -43.008 23.826 -34.719 1.00 27.34 ? 443 GLU A CB 1 ATOM 3486 C CG . GLU A 1 442 ? -43.819 24.810 -33.876 1.00 27.55 ? 443 GLU A CG 1 ATOM 3487 C CD . GLU A 1 442 ? -44.774 25.746 -34.653 1.00 30.74 ? 443 GLU A CD 1 ATOM 3488 O OE1 . GLU A 1 442 ? -44.866 25.744 -35.927 1.00 30.45 ? 443 GLU A OE1 1 ATOM 3489 O OE2 . GLU A 1 442 ? -45.494 26.492 -33.974 1.00 33.43 ? 443 GLU A OE2 1 ATOM 3490 N N . ILE A 1 443 ? -46.222 22.702 -34.996 1.00 26.10 ? 444 ILE A N 1 ATOM 3491 C CA . ILE A 1 443 ? -47.370 22.435 -34.140 1.00 27.96 ? 444 ILE A CA 1 ATOM 3492 C C . ILE A 1 443 ? -47.542 20.923 -33.970 1.00 31.36 ? 444 ILE A C 1 ATOM 3493 O O . ILE A 1 443 ? -47.813 20.435 -32.862 1.00 28.71 ? 444 ILE A O 1 ATOM 3494 C CB . ILE A 1 443 ? -48.653 23.069 -34.678 1.00 26.68 ? 444 ILE A CB 1 ATOM 3495 C CG1 . ILE A 1 443 ? -48.558 24.586 -34.668 1.00 27.61 ? 444 ILE A CG1 1 ATOM 3496 C CG2 . ILE A 1 443 ? -49.853 22.620 -33.894 1.00 29.77 ? 444 ILE A CG2 1 ATOM 3497 C CD1 . ILE A 1 443 ? -49.718 25.245 -35.385 1.00 27.38 ? 444 ILE A CD1 1 ATOM 3498 N N . GLU A 1 444 ? -47.440 20.196 -35.084 1.00 31.27 ? 445 GLU A N 1 ATOM 3499 C CA . GLU A 1 444 ? -47.599 18.754 -35.039 1.00 32.28 ? 445 GLU A CA 1 ATOM 3500 C C . GLU A 1 444 ? -46.606 18.079 -34.099 1.00 29.54 ? 445 GLU A C 1 ATOM 3501 O O . GLU A 1 444 ? -46.931 17.019 -33.553 1.00 27.48 ? 445 GLU A O 1 ATOM 3502 C CB . GLU A 1 444 ? -47.560 18.144 -36.446 1.00 32.74 ? 445 GLU A CB 1 ATOM 3503 C CG . GLU A 1 444 ? -46.364 18.534 -37.280 1.00 34.04 ? 445 GLU A CG 1 ATOM 3504 C CD . GLU A 1 444 ? -46.658 18.359 -38.788 1.00 33.84 ? 445 GLU A CD 1 ATOM 3505 O OE1 . GLU A 1 444 ? -47.611 18.977 -39.278 1.00 32.33 ? 445 GLU A OE1 1 ATOM 3506 O OE2 . GLU A 1 444 ? -45.902 17.629 -39.456 1.00 32.86 ? 445 GLU A OE2 1 ATOM 3507 N N . PHE A 1 445 ? -45.441 18.686 -33.901 1.00 26.41 ? 446 PHE A N 1 ATOM 3508 C CA . PHE A 1 445 ? -44.456 18.131 -32.988 1.00 31.38 ? 446 PHE A CA 1 ATOM 3509 C C . PHE A 1 445 ? -44.809 18.429 -31.532 1.00 34.34 ? 446 PHE A C 1 ATOM 3510 O O . PHE A 1 445 ? -44.583 17.586 -30.660 1.00 32.87 ? 446 PHE A O 1 ATOM 3511 C CB . PHE A 1 445 ? -43.062 18.636 -33.311 1.00 31.22 ? 446 PHE A CB 1 ATOM 3512 C CG . PHE A 1 445 ? -42.493 17.983 -34.546 1.00 34.97 ? 446 PHE A CG 1 ATOM 3513 C CD1 . PHE A 1 445 ? -42.824 18.465 -35.825 1.00 32.80 ? 446 PHE A CD1 1 ATOM 3514 C CD2 . PHE A 1 445 ? -41.706 16.811 -34.452 1.00 35.71 ? 446 PHE A CD2 1 ATOM 3515 C CE1 . PHE A 1 445 ? -42.343 17.847 -36.957 1.00 32.28 ? 446 PHE A CE1 1 ATOM 3516 C CE2 . PHE A 1 445 ? -41.203 16.187 -35.604 1.00 34.71 ? 446 PHE A CE2 1 ATOM 3517 C CZ . PHE A 1 445 ? -41.543 16.692 -36.852 1.00 34.88 ? 446 PHE A CZ 1 ATOM 3518 N N . VAL A 1 446 ? -45.399 19.615 -31.310 1.00 32.48 ? 447 VAL A N 1 ATOM 3519 C CA . VAL A 1 446 ? -45.787 20.078 -29.990 1.00 31.71 ? 447 VAL A CA 1 ATOM 3520 C C . VAL A 1 446 ? -46.983 19.229 -29.540 1.00 33.90 ? 447 VAL A C 1 ATOM 3521 O O . VAL A 1 446 ? -47.114 18.887 -28.344 1.00 27.83 ? 447 VAL A O 1 ATOM 3522 C CB . VAL A 1 446 ? -46.084 21.606 -29.973 1.00 29.46 ? 447 VAL A CB 1 ATOM 3523 C CG1 . VAL A 1 446 ? -46.852 22.034 -28.745 1.00 28.72 ? 447 VAL A CG1 1 ATOM 3524 C CG2 . VAL A 1 446 ? -44.794 22.409 -30.053 1.00 31.06 ? 447 VAL A CG2 1 ATOM 3525 N N . PHE A 1 447 ? -47.840 18.843 -30.484 1.00 30.18 ? 448 PHE A N 1 ATOM 3526 C CA . PHE A 1 447 ? -49.000 18.082 -30.085 1.00 28.29 ? 448 PHE A CA 1 ATOM 3527 C C . PHE A 1 447 ? -48.796 16.537 -30.184 1.00 32.11 ? 448 PHE A C 1 ATOM 3528 O O . PHE A 1 447 ? -49.705 15.773 -29.921 1.00 29.88 ? 448 PHE A O 1 ATOM 3529 C CB . PHE A 1 447 ? -50.216 18.550 -30.837 1.00 29.37 ? 448 PHE A CB 1 ATOM 3530 C CG . PHE A 1 447 ? -50.843 19.784 -30.264 1.00 29.19 ? 448 PHE A CG 1 ATOM 3531 C CD1 . PHE A 1 447 ? -50.354 21.041 -30.579 1.00 28.78 ? 448 PHE A CD1 1 ATOM 3532 C CD2 . PHE A 1 447 ? -51.925 19.691 -29.446 1.00 30.21 ? 448 PHE A CD2 1 ATOM 3533 C CE1 . PHE A 1 447 ? -50.971 22.173 -30.079 1.00 28.70 ? 448 PHE A CE1 1 ATOM 3534 C CE2 . PHE A 1 447 ? -52.562 20.816 -28.946 1.00 31.44 ? 448 PHE A CE2 1 ATOM 3535 C CZ . PHE A 1 447 ? -52.076 22.057 -29.252 1.00 30.46 ? 448 PHE A CZ 1 ATOM 3536 N N . GLY A 1 448 ? -47.597 16.086 -30.531 1.00 32.85 ? 449 GLY A N 1 ATOM 3537 C CA . GLY A 1 448 ? -47.304 14.669 -30.472 1.00 36.39 ? 449 GLY A CA 1 ATOM 3538 C C . GLY A 1 448 ? -47.793 13.752 -31.602 1.00 35.98 ? 449 GLY A C 1 ATOM 3539 O O . GLY A 1 448 ? -47.762 12.529 -31.437 1.00 35.34 ? 449 GLY A O 1 ATOM 3540 N N . LEU A 1 449 ? -48.154 14.319 -32.754 1.00 33.24 ? 450 LEU A N 1 ATOM 3541 C CA . LEU A 1 449 ? -48.657 13.547 -33.913 1.00 36.63 ? 450 LEU A CA 1 ATOM 3542 C C . LEU A 1 449 ? -47.614 12.494 -34.408 1.00 36.48 ? 450 LEU A C 1 ATOM 3543 O O . LEU A 1 449 ? -47.964 11.423 -34.852 1.00 39.25 ? 450 LEU A O 1 ATOM 3544 C CB . LEU A 1 449 ? -49.140 14.474 -35.056 1.00 35.43 ? 450 LEU A CB 1 ATOM 3545 C CG . LEU A 1 449 ? -50.509 15.197 -34.839 1.00 36.96 ? 450 LEU A CG 1 ATOM 3546 C CD1 . LEU A 1 449 ? -51.682 14.258 -34.851 1.00 42.36 ? 450 LEU A CD1 1 ATOM 3547 C CD2 . LEU A 1 449 ? -50.595 15.874 -33.489 1.00 36.19 ? 450 LEU A CD2 1 ATOM 3548 N N . PRO A 1 450 ? -46.345 12.776 -34.283 1.00 33.89 ? 451 PRO A N 1 ATOM 3549 C CA . PRO A 1 450 ? -45.375 11.779 -34.666 1.00 40.79 ? 451 PRO A CA 1 ATOM 3550 C C . PRO A 1 450 ? -45.312 10.503 -33.846 1.00 42.90 ? 451 PRO A C 1 ATOM 3551 O O . PRO A 1 450 ? -44.518 9.626 -34.182 1.00 49.03 ? 451 PRO A O 1 ATOM 3552 C CB . PRO A 1 450 ? -44.042 12.512 -34.512 1.00 35.75 ? 451 PRO A CB 1 ATOM 3553 C CG . PRO A 1 450 ? -44.423 13.862 -34.856 1.00 37.47 ? 451 PRO A CG 1 ATOM 3554 C CD . PRO A 1 450 ? -45.700 14.067 -34.081 1.00 37.38 ? 451 PRO A CD 1 ATOM 3555 N N . LEU A 1 451 ? -46.078 10.397 -32.779 1.00 44.39 ? 452 LEU A N 1 ATOM 3556 C CA . LEU A 1 451 ? -46.074 9.155 -32.028 1.00 43.39 ? 452 LEU A CA 1 ATOM 3557 C C . LEU A 1 451 ? -47.097 8.200 -32.596 1.00 45.96 ? 452 LEU A C 1 ATOM 3558 O O . LEU A 1 451 ? -47.148 7.038 -32.162 1.00 51.83 ? 452 LEU A O 1 ATOM 3559 C CB . LEU A 1 451 ? -46.415 9.340 -30.550 1.00 42.11 ? 452 LEU A CB 1 ATOM 3560 C CG . LEU A 1 451 ? -45.950 10.419 -29.614 1.00 48.64 ? 452 LEU A CG 1 ATOM 3561 C CD1 . LEU A 1 451 ? -46.188 9.979 -28.144 1.00 52.93 ? 452 LEU A CD1 1 ATOM 3562 C CD2 . LEU A 1 451 ? -44.538 10.899 -29.868 1.00 49.84 ? 452 LEU A CD2 1 ATOM 3563 N N . VAL A 1 452 ? -47.964 8.707 -33.469 1.00 42.59 ? 453 VAL A N 1 ATOM 3564 C CA . VAL A 1 452 ? -48.977 7.920 -34.121 1.00 43.71 ? 453 VAL A CA 1 ATOM 3565 C C . VAL A 1 452 ? -48.337 7.251 -35.378 1.00 51.56 ? 453 VAL A C 1 ATOM 3566 O O . VAL A 1 452 ? -47.956 7.914 -36.366 1.00 50.55 ? 453 VAL A O 1 ATOM 3567 C CB . VAL A 1 452 ? -50.212 8.780 -34.465 1.00 49.21 ? 453 VAL A CB 1 ATOM 3568 C CG1 . VAL A 1 452 ? -51.331 7.932 -35.056 1.00 44.69 ? 453 VAL A CG1 1 ATOM 3569 C CG2 . VAL A 1 452 ? -50.759 9.505 -33.228 1.00 52.00 ? 453 VAL A CG2 1 ATOM 3570 N N . LYS A 1 453 ? -48.194 5.931 -35.319 1.00 52.81 ? 454 LYS A N 1 ATOM 3571 C CA . LYS A 1 453 ? -47.448 5.180 -36.327 1.00 61.80 ? 454 LYS A CA 1 ATOM 3572 C C . LYS A 1 453 ? -48.020 5.403 -37.749 1.00 54.53 ? 454 LYS A C 1 ATOM 3573 O O . LYS A 1 453 ? -47.294 5.651 -38.694 1.00 52.06 ? 454 LYS A O 1 ATOM 3574 C CB . LYS A 1 453 ? -47.441 3.703 -35.891 1.00 74.82 ? 454 LYS A CB 1 ATOM 3575 C CG . LYS A 1 453 ? -47.152 2.673 -36.971 1.00 89.27 ? 454 LYS A CG 1 ATOM 3576 C CD . LYS A 1 453 ? -47.802 1.341 -36.606 1.00 93.99 ? 454 LYS A CD 1 ATOM 3577 C CE . LYS A 1 453 ? -47.349 0.232 -37.543 1.00 91.54 ? 454 LYS A CE 1 ATOM 3578 N NZ . LYS A 1 453 ? -47.617 -1.081 -36.910 1.00 92.21 ? 454 LYS A NZ 1 ATOM 3579 N N . GLU A 1 454 ? -49.340 5.413 -37.847 1.00 51.41 ? 455 GLU A N 1 ATOM 3580 C CA . GLU A 1 454 ? -50.060 5.534 -39.101 1.00 54.96 ? 455 GLU A CA 1 ATOM 3581 C C . GLU A 1 454 ? -49.786 6.854 -39.829 1.00 59.79 ? 455 GLU A C 1 ATOM 3582 O O . GLU A 1 454 ? -49.982 6.944 -41.036 1.00 64.07 ? 455 GLU A O 1 ATOM 3583 C CB . GLU A 1 454 ? -51.579 5.424 -38.866 1.00 60.79 ? 455 GLU A CB 1 ATOM 3584 C CG . GLU A 1 454 ? -52.060 4.218 -38.021 1.00 75.05 ? 455 GLU A CG 1 ATOM 3585 C CD . GLU A 1 454 ? -51.783 4.350 -36.506 1.00 79.97 ? 455 GLU A CD 1 ATOM 3586 O OE1 . GLU A 1 454 ? -52.716 4.638 -35.724 1.00 84.51 ? 455 GLU A OE1 1 ATOM 3587 O OE2 . GLU A 1 454 ? -50.619 4.182 -36.084 1.00 80.23 ? 455 GLU A OE2 1 ATOM 3588 N N . LEU A 1 455 ? -49.386 7.898 -39.115 1.00 54.95 ? 456 LEU A N 1 ATOM 3589 C CA . LEU A 1 455 ? -49.156 9.168 -39.765 1.00 49.45 ? 456 LEU A CA 1 ATOM 3590 C C . LEU A 1 455 ? -47.779 9.240 -40.426 1.00 50.83 ? 456 LEU A C 1 ATOM 3591 O O . LEU A 1 455 ? -47.530 10.157 -41.171 1.00 51.11 ? 456 LEU A O 1 ATOM 3592 C CB . LEU A 1 455 ? -49.351 10.322 -38.810 1.00 47.43 ? 456 LEU A CB 1 ATOM 3593 C CG . LEU A 1 455 ? -50.722 10.441 -38.149 1.00 49.84 ? 456 LEU A CG 1 ATOM 3594 C CD1 . LEU A 1 455 ? -50.725 11.665 -37.212 1.00 47.03 ? 456 LEU A CD1 1 ATOM 3595 C CD2 . LEU A 1 455 ? -51.870 10.512 -39.177 1.00 46.36 ? 456 LEU A CD2 1 ATOM 3596 N N . ASN A 1 456 ? -46.962 8.212 -40.229 1.00 52.00 ? 457 ASN A N 1 ATOM 3597 C CA . ASN A 1 456 ? -45.784 7.986 -41.061 1.00 58.70 ? 457 ASN A CA 1 ATOM 3598 C C . ASN A 1 456 ? -44.648 8.987 -40.893 1.00 55.18 ? 457 ASN A C 1 ATOM 3599 O O . ASN A 1 456 ? -44.052 9.435 -41.872 1.00 60.62 ? 457 ASN A O 1 ATOM 3600 C CB . ASN A 1 456 ? -46.187 7.906 -42.536 1.00 65.24 ? 457 ASN A CB 1 ATOM 3601 C CG . ASN A 1 456 ? -47.187 6.800 -42.808 1.00 59.98 ? 457 ASN A CG 1 ATOM 3602 O OD1 . ASN A 1 456 ? -47.164 5.753 -42.160 1.00 52.51 ? 457 ASN A OD1 1 ATOM 3603 N ND2 . ASN A 1 456 ? -48.072 7.026 -43.772 1.00 63.92 ? 457 ASN A ND2 1 ATOM 3604 N N . TYR A 1 457 ? -44.346 9.323 -39.647 1.00 50.20 ? 458 TYR A N 1 ATOM 3605 C CA . TYR A 1 457 ? -43.171 10.142 -39.331 1.00 40.34 ? 458 TYR A CA 1 ATOM 3606 C C . TYR A 1 457 ? -42.064 9.142 -39.158 1.00 40.66 ? 458 TYR A C 1 ATOM 3607 O O . TYR A 1 457 ? -42.325 7.975 -39.032 1.00 40.26 ? 458 TYR A O 1 ATOM 3608 C CB . TYR A 1 457 ? -43.409 10.970 -38.038 1.00 39.62 ? 458 TYR A CB 1 ATOM 3609 C CG . TYR A 1 457 ? -44.426 12.136 -38.184 1.00 35.75 ? 458 TYR A CG 1 ATOM 3610 C CD1 . TYR A 1 457 ? -45.771 11.951 -38.012 1.00 35.25 ? 458 TYR A CD1 1 ATOM 3611 C CD2 . TYR A 1 457 ? -43.999 13.417 -38.504 1.00 33.76 ? 458 TYR A CD2 1 ATOM 3612 C CE1 . TYR A 1 457 ? -46.679 12.987 -38.143 1.00 32.24 ? 458 TYR A CE1 1 ATOM 3613 C CE2 . TYR A 1 457 ? -44.906 14.464 -38.632 1.00 32.05 ? 458 TYR A CE2 1 ATOM 3614 C CZ . TYR A 1 457 ? -46.240 14.255 -38.461 1.00 32.10 ? 458 TYR A CZ 1 ATOM 3615 O OH . TYR A 1 457 ? -47.136 15.340 -38.603 1.00 31.56 ? 458 TYR A OH 1 ATOM 3616 N N . THR A 1 458 ? -40.820 9.581 -39.157 1.00 42.61 ? 459 THR A N 1 ATOM 3617 C CA . THR A 1 458 ? -39.730 8.720 -38.774 1.00 40.98 ? 459 THR A CA 1 ATOM 3618 C C . THR A 1 458 ? -39.570 8.560 -37.249 1.00 48.74 ? 459 THR A C 1 ATOM 3619 O O . THR A 1 458 ? -40.033 9.362 -36.456 1.00 47.63 ? 459 THR A O 1 ATOM 3620 C CB . THR A 1 458 ? -38.448 9.336 -39.266 1.00 45.15 ? 459 THR A CB 1 ATOM 3621 O OG1 . THR A 1 458 ? -38.211 10.589 -38.577 1.00 39.20 ? 459 THR A OG1 1 ATOM 3622 C CG2 . THR A 1 458 ? -38.519 9.496 -40.842 1.00 40.80 ? 459 THR A CG2 1 ATOM 3623 N N . ALA A 1 459 ? -38.854 7.538 -36.844 1.00 49.24 ? 460 ALA A N 1 ATOM 3624 C CA . ALA A 1 459 ? -38.521 7.348 -35.436 1.00 47.98 ? 460 ALA A CA 1 ATOM 3625 C C . ALA A 1 459 ? -37.807 8.566 -34.830 1.00 39.83 ? 460 ALA A C 1 ATOM 3626 O O . ALA A 1 459 ? -38.007 8.892 -33.686 1.00 37.86 ? 460 ALA A O 1 ATOM 3627 C CB . ALA A 1 459 ? -37.638 6.094 -35.266 1.00 41.11 ? 460 ALA A CB 1 ATOM 3628 N N . GLU A 1 460 ? -36.930 9.208 -35.567 1.00 44.47 ? 461 GLU A N 1 ATOM 3629 C CA . GLU A 1 460 ? -36.202 10.371 -35.001 1.00 46.32 ? 461 GLU A CA 1 ATOM 3630 C C . GLU A 1 460 ? -37.143 11.623 -34.843 1.00 43.86 ? 461 GLU A C 1 ATOM 3631 O O . GLU A 1 460 ? -36.919 12.461 -33.934 1.00 36.36 ? 461 GLU A O 1 ATOM 3632 C CB . GLU A 1 460 ? -34.866 10.682 -35.743 1.00 52.68 ? 461 GLU A CB 1 ATOM 3633 C CG . GLU A 1 460 ? -34.857 10.383 -37.223 1.00 67.47 ? 461 GLU A CG 1 ATOM 3634 C CD . GLU A 1 460 ? -34.610 8.903 -37.517 1.00 66.41 ? 461 GLU A CD 1 ATOM 3635 O OE1 . GLU A 1 460 ? -33.478 8.479 -37.278 1.00 72.39 ? 461 GLU A OE1 1 ATOM 3636 O OE2 . GLU A 1 460 ? -35.542 8.168 -37.961 1.00 62.00 ? 461 GLU A OE2 1 ATOM 3637 N N . GLU A 1 461 ? -38.197 11.681 -35.667 1.00 34.77 ? 462 GLU A N 1 ATOM 3638 C CA . GLU A 1 461 ? -39.264 12.636 -35.523 1.00 39.30 ? 462 GLU A CA 1 ATOM 3639 C C . GLU A 1 461 ? -40.187 12.314 -34.342 1.00 45.38 ? 462 GLU A C 1 ATOM 3640 O O . GLU A 1 461 ? -40.788 13.220 -33.729 1.00 38.98 ? 462 GLU A O 1 ATOM 3641 C CB . GLU A 1 461 ? -40.110 12.684 -36.822 1.00 36.67 ? 462 GLU A CB 1 ATOM 3642 C CG . GLU A 1 461 ? -39.354 13.389 -37.908 1.00 33.95 ? 462 GLU A CG 1 ATOM 3643 C CD . GLU A 1 461 ? -39.989 13.425 -39.298 1.00 34.71 ? 462 GLU A CD 1 ATOM 3644 O OE1 . GLU A 1 461 ? -40.879 12.611 -39.646 1.00 37.06 ? 462 GLU A OE1 1 ATOM 3645 O OE2 . GLU A 1 461 ? -39.535 14.316 -40.058 1.00 31.07 ? 462 GLU A OE2 1 ATOM 3646 N N . GLU A 1 462 ? -40.333 11.027 -34.025 1.00 45.53 ? 463 GLU A N 1 ATOM 3647 C CA . GLU A 1 462 ? -41.073 10.654 -32.818 1.00 43.45 ? 463 GLU A CA 1 ATOM 3648 C C . GLU A 1 462 ? -40.266 11.139 -31.637 1.00 40.07 ? 463 GLU A C 1 ATOM 3649 O O . GLU A 1 462 ? -40.788 11.794 -30.736 1.00 40.50 ? 463 GLU A O 1 ATOM 3650 C CB . GLU A 1 462 ? -41.344 9.160 -32.710 1.00 48.61 ? 463 GLU A CB 1 ATOM 3651 C CG . GLU A 1 462 ? -41.873 8.761 -31.319 1.00 54.48 ? 463 GLU A CG 1 ATOM 3652 C CD . GLU A 1 462 ? -42.325 7.304 -31.189 1.00 53.48 ? 463 GLU A CD 1 ATOM 3653 O OE1 . GLU A 1 462 ? -42.118 6.489 -32.110 1.00 54.75 ? 463 GLU A OE1 1 ATOM 3654 O OE2 . GLU A 1 462 ? -42.895 6.971 -30.130 1.00 57.33 ? 463 GLU A OE2 1 ATOM 3655 N N . ALA A 1 463 ? -38.980 10.875 -31.670 1.00 32.60 ? 464 ALA A N 1 ATOM 3656 C CA . ALA A 1 463 ? -38.156 11.264 -30.564 1.00 37.71 ? 464 ALA A CA 1 ATOM 3657 C C . ALA A 1 463 ? -38.118 12.798 -30.418 1.00 43.78 ? 464 ALA A C 1 ATOM 3658 O O . ALA A 1 463 ? -37.935 13.325 -29.305 1.00 38.07 ? 464 ALA A O 1 ATOM 3659 C CB . ALA A 1 463 ? -36.722 10.706 -30.716 1.00 34.39 ? 464 ALA A CB 1 ATOM 3660 N N . LEU A 1 464 ? -38.235 13.524 -31.536 1.00 37.88 ? 465 LEU A N 1 ATOM 3661 C CA . LEU A 1 464 ? -38.093 14.981 -31.436 1.00 35.53 ? 465 LEU A CA 1 ATOM 3662 C C . LEU A 1 464 ? -39.365 15.552 -30.786 1.00 30.10 ? 465 LEU A C 1 ATOM 3663 O O . LEU A 1 464 ? -39.340 16.413 -29.888 1.00 31.53 ? 465 LEU A O 1 ATOM 3664 C CB . LEU A 1 464 ? -37.814 15.581 -32.841 1.00 34.82 ? 465 LEU A CB 1 ATOM 3665 C CG . LEU A 1 464 ? -38.067 17.049 -32.945 1.00 34.80 ? 465 LEU A CG 1 ATOM 3666 C CD1 . LEU A 1 464 ? -37.107 17.814 -32.040 1.00 36.32 ? 465 LEU A CD1 1 ATOM 3667 C CD2 . LEU A 1 464 ? -37.913 17.453 -34.393 1.00 40.40 ? 465 LEU A CD2 1 ATOM 3668 N N . SER A 1 465 ? -40.475 15.040 -31.254 1.00 25.79 ? 466 SER A N 1 ATOM 3669 C CA . SER A 1 465 ? -41.750 15.334 -30.682 1.00 27.64 ? 466 SER A CA 1 ATOM 3670 C C . SER A 1 465 ? -41.792 15.051 -29.187 1.00 33.40 ? 466 SER A C 1 ATOM 3671 O O . SER A 1 465 ? -42.196 15.936 -28.415 1.00 39.18 ? 466 SER A O 1 ATOM 3672 C CB . SER A 1 465 ? -42.826 14.582 -31.392 1.00 25.30 ? 466 SER A CB 1 ATOM 3673 O OG . SER A 1 465 ? -44.107 14.922 -30.924 1.00 27.71 ? 466 SER A OG 1 ATOM 3674 N N . ARG A 1 466 ? -41.362 13.874 -28.757 1.00 38.89 ? 467 ARG A N 1 ATOM 3675 C CA . ARG A 1 466 ? -41.388 13.533 -27.295 1.00 40.12 ? 467 ARG A CA 1 ATOM 3676 C C . ARG A 1 466 ? -40.552 14.536 -26.503 1.00 34.90 ? 467 ARG A C 1 ATOM 3677 O O . ARG A 1 466 ? -40.921 15.028 -25.464 1.00 39.14 ? 467 ARG A O 1 ATOM 3678 C CB . ARG A 1 466 ? -40.864 12.116 -27.044 1.00 39.76 ? 467 ARG A CB 1 ATOM 3679 C CG . ARG A 1 466 ? -41.815 11.018 -27.516 1.00 38.33 ? 467 ARG A CG 1 ATOM 3680 C CD . ARG A 1 466 ? -41.328 9.603 -27.118 1.00 37.86 ? 467 ARG A CD 1 ATOM 3681 N NE . ARG A 1 466 ? -42.337 8.600 -27.458 1.00 33.82 ? 467 ARG A NE 1 ATOM 3682 C CZ . ARG A 1 466 ? -43.418 8.370 -26.749 1.00 36.52 ? 467 ARG A CZ 1 ATOM 3683 N NH1 . ARG A 1 466 ? -43.611 9.037 -25.625 1.00 34.28 ? 467 ARG A NH1 1 ATOM 3684 N NH2 . ARG A 1 466 ? -44.357 7.513 -27.184 1.00 39.12 ? 467 ARG A NH2 1 ATOM 3685 N N . ARG A 1 467 ? -39.451 14.914 -27.070 1.00 32.32 ? 468 ARG A N 1 ATOM 3686 C CA . ARG A 1 467 ? -38.585 15.866 -26.432 1.00 35.14 ? 468 ARG A CA 1 ATOM 3687 C C . ARG A 1 467 ? -39.208 17.295 -26.393 1.00 34.94 ? 468 ARG A C 1 ATOM 3688 O O . ARG A 1 467 ? -39.088 18.020 -25.424 1.00 30.30 ? 468 ARG A O 1 ATOM 3689 C CB . ARG A 1 467 ? -37.331 15.880 -27.248 1.00 38.10 ? 468 ARG A CB 1 ATOM 3690 C CG . ARG A 1 467 ? -36.075 16.213 -26.526 1.00 45.87 ? 468 ARG A CG 1 ATOM 3691 C CD . ARG A 1 467 ? -34.928 15.973 -27.506 1.00 52.20 ? 468 ARG A CD 1 ATOM 3692 N NE . ARG A 1 467 ? -34.338 17.260 -27.847 1.00 62.77 ? 468 ARG A NE 1 ATOM 3693 C CZ . ARG A 1 467 ? -33.972 17.640 -29.058 1.00 62.70 ? 468 ARG A CZ 1 ATOM 3694 N NH1 . ARG A 1 467 ? -34.142 16.808 -30.089 1.00 59.71 ? 468 ARG A NH1 1 ATOM 3695 N NH2 . ARG A 1 467 ? -33.414 18.858 -29.211 1.00 63.34 ? 468 ARG A NH2 1 ATOM 3696 N N . ILE A 1 468 ? -39.894 17.687 -27.454 1.00 30.67 ? 469 ILE A N 1 ATOM 3697 C CA . ILE A 1 468 ? -40.540 18.989 -27.446 1.00 30.38 ? 469 ILE A CA 1 ATOM 3698 C C . ILE A 1 468 ? -41.678 18.995 -26.478 1.00 27.65 ? 469 ILE A C 1 ATOM 3699 O O . ILE A 1 468 ? -41.889 19.948 -25.710 1.00 29.97 ? 469 ILE A O 1 ATOM 3700 C CB . ILE A 1 468 ? -40.997 19.403 -28.890 1.00 28.36 ? 469 ILE A CB 1 ATOM 3701 C CG1 . ILE A 1 468 ? -39.772 19.870 -29.670 1.00 27.49 ? 469 ILE A CG1 1 ATOM 3702 C CG2 . ILE A 1 468 ? -42.034 20.481 -28.868 1.00 28.72 ? 469 ILE A CG2 1 ATOM 3703 C CD1 . ILE A 1 468 ? -40.020 19.938 -31.166 1.00 29.89 ? 469 ILE A CD1 1 ATOM 3704 N N . MET A 1 469 ? -42.443 17.938 -26.495 1.00 30.68 ? 470 MET A N 1 ATOM 3705 C CA . MET A 1 469 ? -43.596 17.897 -25.600 1.00 32.51 ? 470 MET A CA 1 ATOM 3706 C C . MET A 1 469 ? -43.129 17.984 -24.136 1.00 35.65 ? 470 MET A C 1 ATOM 3707 O O . MET A 1 469 ? -43.821 18.548 -23.286 1.00 31.08 ? 470 MET A O 1 ATOM 3708 C CB . MET A 1 469 ? -44.390 16.616 -25.789 1.00 31.83 ? 470 MET A CB 1 ATOM 3709 C CG . MET A 1 469 ? -45.336 16.638 -26.918 1.00 31.24 ? 470 MET A CG 1 ATOM 3710 S SD . MET A 1 469 ? -46.526 15.273 -26.948 1.00 39.41 ? 470 MET A SD 1 ATOM 3711 C CE . MET A 1 469 ? -45.400 13.964 -27.288 1.00 32.69 ? 470 MET A CE 1 ATOM 3712 N N . HIS A 1 470 ? -41.996 17.356 -23.851 1.00 33.31 ? 471 HIS A N 1 ATOM 3713 C CA . HIS A 1 470 ? -41.538 17.275 -22.507 1.00 35.54 ? 471 HIS A CA 1 ATOM 3714 C C . HIS A 1 470 ? -40.893 18.613 -22.132 1.00 33.41 ? 471 HIS A C 1 ATOM 3715 O O . HIS A 1 470 ? -41.077 19.064 -21.019 1.00 31.02 ? 471 HIS A O 1 ATOM 3716 C CB . HIS A 1 470 ? -40.595 16.063 -22.307 1.00 39.71 ? 471 HIS A CB 1 ATOM 3717 C CG . HIS A 1 470 ? -40.264 15.797 -20.870 1.00 45.53 ? 471 HIS A CG 1 ATOM 3718 N ND1 . HIS A 1 470 ? -41.242 15.519 -19.924 1.00 46.02 ? 471 HIS A ND1 1 ATOM 3719 C CD2 . HIS A 1 470 ? -39.082 15.815 -20.199 1.00 40.83 ? 471 HIS A CD2 1 ATOM 3720 C CE1 . HIS A 1 470 ? -40.672 15.361 -18.741 1.00 40.28 ? 471 HIS A CE1 1 ATOM 3721 N NE2 . HIS A 1 470 ? -39.369 15.543 -18.874 1.00 39.67 ? 471 HIS A NE2 1 ATOM 3722 N N . TYR A 1 471 ? -40.149 19.254 -23.032 1.00 31.43 ? 472 TYR A N 1 ATOM 3723 C CA . TYR A 1 471 ? -39.755 20.656 -22.780 1.00 32.95 ? 472 TYR A CA 1 ATOM 3724 C C . TYR A 1 471 ? -40.982 21.565 -22.479 1.00 33.69 ? 472 TYR A C 1 ATOM 3725 O O . TYR A 1 471 ? -40.945 22.365 -21.557 1.00 35.13 ? 472 TYR A O 1 ATOM 3726 C CB . TYR A 1 471 ? -39.088 21.267 -23.950 1.00 32.79 ? 472 TYR A CB 1 ATOM 3727 C CG . TYR A 1 471 ? -37.681 20.813 -24.266 1.00 37.34 ? 472 TYR A CG 1 ATOM 3728 C CD1 . TYR A 1 471 ? -36.741 20.549 -23.266 1.00 42.10 ? 472 TYR A CD1 1 ATOM 3729 C CD2 . TYR A 1 471 ? -37.257 20.733 -25.602 1.00 40.08 ? 472 TYR A CD2 1 ATOM 3730 C CE1 . TYR A 1 471 ? -35.428 20.177 -23.577 1.00 37.72 ? 472 TYR A CE1 1 ATOM 3731 C CE2 . TYR A 1 471 ? -35.975 20.372 -25.918 1.00 39.98 ? 472 TYR A CE2 1 ATOM 3732 C CZ . TYR A 1 471 ? -35.076 20.090 -24.893 1.00 41.12 ? 472 TYR A CZ 1 ATOM 3733 O OH . TYR A 1 471 ? -33.838 19.705 -25.226 1.00 47.35 ? 472 TYR A OH 1 ATOM 3734 N N . TRP A 1 472 ? -42.029 21.445 -23.288 1.00 30.24 ? 473 TRP A N 1 ATOM 3735 C CA . TRP A 1 472 ? -43.198 22.311 -23.158 1.00 30.58 ? 473 TRP A CA 1 ATOM 3736 C C . TRP A 1 472 ? -43.929 22.096 -21.837 1.00 31.87 ? 473 TRP A C 1 ATOM 3737 O O . TRP A 1 472 ? -44.334 23.052 -21.174 1.00 29.06 ? 473 TRP A O 1 ATOM 3738 C CB . TRP A 1 472 ? -44.158 22.092 -24.330 1.00 28.13 ? 473 TRP A CB 1 ATOM 3739 C CG . TRP A 1 472 ? -44.046 23.133 -25.400 1.00 31.89 ? 473 TRP A CG 1 ATOM 3740 C CD1 . TRP A 1 472 ? -45.039 23.950 -25.857 1.00 30.16 ? 473 TRP A CD1 1 ATOM 3741 C CD2 . TRP A 1 472 ? -42.873 23.471 -26.151 1.00 26.62 ? 473 TRP A CD2 1 ATOM 3742 N NE1 . TRP A 1 472 ? -44.558 24.775 -26.844 1.00 27.76 ? 473 TRP A NE1 1 ATOM 3743 C CE2 . TRP A 1 472 ? -43.230 24.500 -27.044 1.00 28.03 ? 473 TRP A CE2 1 ATOM 3744 C CE3 . TRP A 1 472 ? -41.556 23.002 -26.155 1.00 26.67 ? 473 TRP A CE3 1 ATOM 3745 C CZ2 . TRP A 1 472 ? -42.319 25.069 -27.931 1.00 28.32 ? 473 TRP A CZ2 1 ATOM 3746 C CZ3 . TRP A 1 472 ? -40.652 23.568 -27.036 1.00 26.05 ? 473 TRP A CZ3 1 ATOM 3747 C CH2 . TRP A 1 472 ? -41.038 24.590 -27.911 1.00 28.58 ? 473 TRP A CH2 1 ATOM 3748 N N . ALA A 1 473 ? -44.095 20.833 -21.465 1.00 29.69 ? 474 ALA A N 1 ATOM 3749 C CA . ALA A 1 473 ? -44.809 20.463 -20.246 1.00 30.38 ? 474 ALA A CA 1 ATOM 3750 C C . ALA A 1 473 ? -43.985 20.687 -19.004 1.00 28.71 ? 474 ALA A C 1 ATOM 3751 O O . ALA A 1 473 ? -44.500 21.167 -18.056 1.00 27.59 ? 474 ALA A O 1 ATOM 3752 C CB . ALA A 1 473 ? -45.287 19.051 -20.285 1.00 31.99 ? 474 ALA A CB 1 ATOM 3753 N N . THR A 1 474 ? -42.698 20.413 -19.035 1.00 31.28 ? 475 THR A N 1 ATOM 3754 C CA . THR A 1 474 ? -41.860 20.685 -17.888 1.00 29.77 ? 475 THR A CA 1 ATOM 3755 C C . THR A 1 474 ? -41.761 22.172 -17.648 1.00 34.79 ? 475 THR A C 1 ATOM 3756 O O . THR A 1 474 ? -41.732 22.667 -16.485 1.00 37.60 ? 475 THR A O 1 ATOM 3757 C CB . THR A 1 474 ? -40.477 20.106 -18.102 1.00 29.99 ? 475 THR A CB 1 ATOM 3758 O OG1 . THR A 1 474 ? -40.611 18.703 -18.410 1.00 28.17 ? 475 THR A OG1 1 ATOM 3759 C CG2 . THR A 1 474 ? -39.601 20.322 -16.922 1.00 29.46 ? 475 THR A CG2 1 ATOM 3760 N N . PHE A 1 475 ? -41.695 22.922 -18.731 1.00 35.38 ? 476 PHE A N 1 ATOM 3761 C CA . PHE A 1 475 ? -41.730 24.370 -18.567 1.00 29.62 ? 476 PHE A CA 1 ATOM 3762 C C . PHE A 1 475 ? -43.076 24.806 -18.001 1.00 27.74 ? 476 PHE A C 1 ATOM 3763 O O . PHE A 1 475 ? -43.122 25.729 -17.185 1.00 26.73 ? 476 PHE A O 1 ATOM 3764 C CB . PHE A 1 475 ? -41.453 25.063 -19.888 1.00 33.11 ? 476 PHE A CB 1 ATOM 3765 C CG . PHE A 1 475 ? -41.740 26.518 -19.865 1.00 30.42 ? 476 PHE A CG 1 ATOM 3766 C CD1 . PHE A 1 475 ? -40.800 27.388 -19.391 1.00 30.80 ? 476 PHE A CD1 1 ATOM 3767 C CD2 . PHE A 1 475 ? -42.981 26.981 -20.236 1.00 29.04 ? 476 PHE A CD2 1 ATOM 3768 C CE1 . PHE A 1 475 ? -41.065 28.728 -19.319 1.00 29.53 ? 476 PHE A CE1 1 ATOM 3769 C CE2 . PHE A 1 475 ? -43.256 28.312 -20.144 1.00 31.31 ? 476 PHE A CE2 1 ATOM 3770 C CZ . PHE A 1 475 ? -42.291 29.187 -19.724 1.00 29.45 ? 476 PHE A CZ 1 ATOM 3771 N N . ALA A 1 476 ? -44.190 24.191 -18.405 1.00 25.32 ? 477 ALA A N 1 ATOM 3772 C CA . ALA A 1 476 ? -45.471 24.676 -17.895 1.00 29.05 ? 477 ALA A CA 1 ATOM 3773 C C . ALA A 1 476 ? -45.582 24.463 -16.361 1.00 36.58 ? 477 ALA A C 1 ATOM 3774 O O . ALA A 1 476 ? -46.154 25.288 -15.615 1.00 31.55 ? 477 ALA A O 1 ATOM 3775 C CB . ALA A 1 476 ? -46.651 24.033 -18.608 1.00 28.96 ? 477 ALA A CB 1 ATOM 3776 N N . LYS A 1 477 ? -44.987 23.353 -15.944 1.00 40.71 ? 478 LYS A N 1 ATOM 3777 C CA . LYS A 1 477 ? -45.083 22.855 -14.610 1.00 46.71 ? 478 LYS A CA 1 ATOM 3778 C C . LYS A 1 477 ? -44.127 23.617 -13.672 1.00 44.19 ? 478 LYS A C 1 ATOM 3779 O O . LYS A 1 477 ? -44.529 23.990 -12.556 1.00 36.42 ? 478 LYS A O 1 ATOM 3780 C CB . LYS A 1 477 ? -44.772 21.358 -14.637 1.00 54.63 ? 478 LYS A CB 1 ATOM 3781 C CG . LYS A 1 477 ? -44.793 20.667 -13.272 1.00 70.13 ? 478 LYS A CG 1 ATOM 3782 C CD . LYS A 1 477 ? -44.699 19.148 -13.426 1.00 76.71 ? 478 LYS A CD 1 ATOM 3783 C CE . LYS A 1 477 ? -43.263 18.627 -13.312 1.00 79.47 ? 478 LYS A CE 1 ATOM 3784 N NZ . LYS A 1 477 ? -42.942 18.222 -11.914 1.00 80.42 ? 478 LYS A NZ 1 ATOM 3785 N N . THR A 1 478 ? -42.889 23.836 -14.134 1.00 35.81 ? 479 THR A N 1 ATOM 3786 C CA . THR A 1 478 ? -41.872 24.408 -13.320 1.00 31.40 ? 479 THR A CA 1 ATOM 3787 C C . THR A 1 478 ? -41.350 25.775 -13.720 1.00 36.30 ? 479 THR A C 1 ATOM 3788 O O . THR A 1 478 ? -40.685 26.384 -12.929 1.00 36.09 ? 479 THR A O 1 ATOM 3789 C CB . THR A 1 478 ? -40.633 23.529 -13.288 1.00 32.19 ? 479 THR A CB 1 ATOM 3790 O OG1 . THR A 1 478 ? -39.901 23.635 -14.508 1.00 31.39 ? 479 THR A OG1 1 ATOM 3791 C CG2 . THR A 1 478 ? -40.979 22.041 -12.993 1.00 32.44 ? 479 THR A CG2 1 ATOM 3792 N N . GLY A 1 479 ? -41.541 26.237 -14.956 1.00 33.03 ? 480 GLY A N 1 ATOM 3793 C CA . GLY A 1 479 ? -40.936 27.491 -15.378 1.00 30.42 ? 480 GLY A CA 1 ATOM 3794 C C . GLY A 1 479 ? -39.598 27.327 -15.987 1.00 27.55 ? 480 GLY A C 1 ATOM 3795 O O . GLY A 1 479 ? -38.917 28.300 -16.334 1.00 28.00 ? 480 GLY A O 1 ATOM 3796 N N . ASN A 1 480 ? -39.235 26.068 -16.187 1.00 32.74 ? 481 ASN A N 1 ATOM 3797 C CA . ASN A 1 480 ? -37.964 25.698 -16.816 1.00 31.89 ? 481 ASN A CA 1 ATOM 3798 C C . ASN A 1 480 ? -38.147 24.422 -17.679 1.00 30.86 ? 481 ASN A C 1 ATOM 3799 O O . ASN A 1 480 ? -38.648 23.419 -17.176 1.00 35.26 ? 481 ASN A O 1 ATOM 3800 C CB . ASN A 1 480 ? -36.950 25.479 -15.696 1.00 35.82 ? 481 ASN A CB 1 ATOM 3801 C CG . ASN A 1 480 ? -35.592 25.115 -16.206 1.00 39.16 ? 481 ASN A CG 1 ATOM 3802 O OD1 . ASN A 1 480 ? -35.427 24.591 -17.312 1.00 42.87 ? 481 ASN A OD1 1 ATOM 3803 N ND2 . ASN A 1 480 ? -34.607 25.398 -15.414 1.00 40.35 ? 481 ASN A ND2 1 ATOM 3804 N N . PRO A 1 481 ? -37.803 24.461 -18.988 1.00 32.40 ? 482 PRO A N 1 ATOM 3805 C CA . PRO A 1 481 ? -38.040 23.261 -19.839 1.00 39.14 ? 482 PRO A CA 1 ATOM 3806 C C . PRO A 1 481 ? -37.143 22.045 -19.468 1.00 34.64 ? 482 PRO A C 1 ATOM 3807 O O . PRO A 1 481 ? -37.412 20.898 -19.866 1.00 34.00 ? 482 PRO A O 1 ATOM 3808 C CB . PRO A 1 481 ? -37.669 23.753 -21.254 1.00 35.32 ? 482 PRO A CB 1 ATOM 3809 C CG . PRO A 1 481 ? -36.614 24.778 -20.980 1.00 35.63 ? 482 PRO A CG 1 ATOM 3810 C CD . PRO A 1 481 ? -37.064 25.493 -19.731 1.00 32.62 ? 482 PRO A CD 1 ATOM 3811 N N . ASN A 1 482 ? -36.061 22.333 -18.764 1.00 32.84 ? 483 ASN A N 1 ATOM 3812 C CA . ASN A 1 482 ? -35.082 21.309 -18.382 1.00 36.94 ? 483 ASN A CA 1 ATOM 3813 C C . ASN A 1 482 ? -35.485 20.552 -17.099 1.00 36.31 ? 483 ASN A C 1 ATOM 3814 O O . ASN A 1 482 ? -35.986 21.137 -16.114 1.00 34.39 ? 483 ASN A O 1 ATOM 3815 C CB . ASN A 1 482 ? -33.760 21.968 -18.124 1.00 36.13 ? 483 ASN A CB 1 ATOM 3816 C CG . ASN A 1 482 ? -33.227 22.682 -19.335 1.00 38.03 ? 483 ASN A CG 1 ATOM 3817 O OD1 . ASN A 1 482 ? -32.741 22.044 -20.294 1.00 38.68 ? 483 ASN A OD1 1 ATOM 3818 N ND2 . ASN A 1 482 ? -33.237 24.013 -19.270 1.00 33.80 ? 483 ASN A ND2 1 ATOM 3819 N N . GLU A 1 483 ? -35.314 19.256 -17.102 1.00 45.76 ? 484 GLU A N 1 ATOM 3820 C CA . GLU A 1 483 ? -35.646 18.497 -15.865 1.00 58.64 ? 484 GLU A CA 1 ATOM 3821 C C . GLU A 1 483 ? -34.502 18.653 -14.864 1.00 52.75 ? 484 GLU A C 1 ATOM 3822 O O . GLU A 1 483 ? -33.317 18.505 -15.254 1.00 46.24 ? 484 GLU A O 1 ATOM 3823 C CB . GLU A 1 483 ? -35.957 17.035 -16.159 1.00 65.91 ? 484 GLU A CB 1 ATOM 3824 C CG . GLU A 1 483 ? -36.800 16.359 -15.084 1.00 72.07 ? 484 GLU A CG 1 ATOM 3825 C CD . GLU A 1 483 ? -37.892 15.539 -15.692 1.00 74.92 ? 484 GLU A CD 1 ATOM 3826 O OE1 . GLU A 1 483 ? -39.016 15.570 -15.159 1.00 100.38 ? 484 GLU A OE1 1 ATOM 3827 O OE2 . GLU A 1 483 ? -37.648 14.912 -16.739 1.00 71.13 ? 484 GLU A OE2 1 ATOM 3828 N N . PRO A 1 484 ? -34.843 19.018 -13.599 0.50 49.91 ? 485 PRO A N 1 ATOM 3829 C CA . PRO A 1 484 ? -33.805 19.252 -12.605 0.50 48.45 ? 485 PRO A CA 1 ATOM 3830 C C . PRO A 1 484 ? -32.973 17.989 -12.465 0.50 44.36 ? 485 PRO A C 1 ATOM 3831 O O . PRO A 1 484 ? -33.549 16.889 -12.353 0.50 41.40 ? 485 PRO A O 1 ATOM 3832 C CB . PRO A 1 484 ? -34.612 19.503 -11.324 0.50 48.30 ? 485 PRO A CB 1 ATOM 3833 C CG . PRO A 1 484 ? -35.845 18.684 -11.525 0.50 48.30 ? 485 PRO A CG 1 ATOM 3834 C CD . PRO A 1 484 ? -36.174 18.941 -12.963 0.50 49.05 ? 485 PRO A CD 1 ATOM 3835 N N . HIS A 1 485 ? -31.656 18.153 -12.555 0.50 42.29 ? 486 HIS A N 1 ATOM 3836 C CA . HIS A 1 485 ? -30.665 17.093 -12.318 0.50 44.78 ? 486 HIS A CA 1 ATOM 3837 C C . HIS A 1 485 ? -30.576 15.986 -13.370 0.50 44.26 ? 486 HIS A C 1 ATOM 3838 O O . HIS A 1 485 ? -29.769 15.078 -13.199 0.50 45.02 ? 486 HIS A O 1 ATOM 3839 C CB . HIS A 1 485 ? -30.816 16.410 -10.927 0.50 48.87 ? 486 HIS A CB 1 ATOM 3840 C CG . HIS A 1 485 ? -31.042 17.353 -9.776 0.50 52.89 ? 486 HIS A CG 1 ATOM 3841 N ND1 . HIS A 1 485 ? -30.299 18.501 -9.583 0.50 57.73 ? 486 HIS A ND1 1 ATOM 3842 C CD2 . HIS A 1 485 ? -31.929 17.303 -8.747 0.50 51.57 ? 486 HIS A CD2 1 ATOM 3843 C CE1 . HIS A 1 485 ? -30.729 19.126 -8.497 0.50 57.50 ? 486 HIS A CE1 1 ATOM 3844 N NE2 . HIS A 1 485 ? -31.717 18.419 -7.972 0.50 54.57 ? 486 HIS A NE2 1 ATOM 3845 N N . SER A 1 486 ? -31.367 16.017 -14.438 0.50 43.62 ? 487 SER A N 1 ATOM 3846 C CA . SER A 1 486 ? -31.210 15.016 -15.517 0.50 43.19 ? 487 SER A CA 1 ATOM 3847 C C . SER A 1 486 ? -29.853 15.088 -16.212 0.50 40.83 ? 487 SER A C 1 ATOM 3848 O O . SER A 1 486 ? -29.084 15.978 -15.946 0.50 41.26 ? 487 SER A O 1 ATOM 3849 C CB . SER A 1 486 ? -32.311 15.167 -16.556 0.50 43.49 ? 487 SER A CB 1 ATOM 3850 O OG . SER A 1 486 ? -31.766 15.427 -17.839 0.50 44.02 ? 487 SER A OG 1 ATOM 3851 N N . GLN A 1 487 ? -29.578 14.148 -17.110 0.50 46.51 ? 488 GLN A N 1 ATOM 3852 C CA . GLN A 1 487 ? -28.291 14.084 -17.857 0.50 49.59 ? 488 GLN A CA 1 ATOM 3853 C C . GLN A 1 487 ? -28.319 14.646 -19.290 0.50 46.21 ? 488 GLN A C 1 ATOM 3854 O O . GLN A 1 487 ? -27.283 14.715 -19.960 0.50 39.12 ? 488 GLN A O 1 ATOM 3855 C CB . GLN A 1 487 ? -27.807 12.631 -17.951 0.50 52.54 ? 488 GLN A CB 1 ATOM 3856 C CG . GLN A 1 487 ? -27.557 11.959 -16.606 0.50 55.79 ? 488 GLN A CG 1 ATOM 3857 C CD . GLN A 1 487 ? -26.253 12.400 -15.970 0.50 55.89 ? 488 GLN A CD 1 ATOM 3858 O OE1 . GLN A 1 487 ? -25.181 12.062 -16.449 0.50 57.31 ? 488 GLN A OE1 1 ATOM 3859 N NE2 . GLN A 1 487 ? -26.342 13.154 -14.883 0.50 55.23 ? 488 GLN A NE2 1 ATOM 3860 N N . GLU A 1 488 ? -29.502 15.030 -19.756 0.50 44.81 ? 489 GLU A N 1 ATOM 3861 C CA . GLU A 1 488 ? -29.654 15.579 -21.095 0.50 43.60 ? 489 GLU A CA 1 ATOM 3862 C C . GLU A 1 488 ? -28.925 16.882 -21.224 0.50 42.81 ? 489 GLU A C 1 ATOM 3863 O O . GLU A 1 488 ? -28.549 17.520 -20.254 0.50 35.70 ? 489 GLU A O 1 ATOM 3864 C CB . GLU A 1 488 ? -31.115 15.863 -21.402 0.50 46.46 ? 489 GLU A CB 1 ATOM 3865 C CG . GLU A 1 488 ? -32.054 14.750 -21.019 0.50 48.24 ? 489 GLU A CG 1 ATOM 3866 C CD . GLU A 1 488 ? -31.485 13.457 -21.492 0.50 51.20 ? 489 GLU A CD 1 ATOM 3867 O OE1 . GLU A 1 488 ? -30.700 13.540 -22.450 0.50 50.95 ? 489 GLU A OE1 1 ATOM 3868 O OE2 . GLU A 1 488 ? -31.780 12.399 -20.897 0.50 53.92 ? 489 GLU A OE2 1 ATOM 3869 N N . SER A 1 489 ? -28.769 17.308 -22.458 1.00 51.69 ? 490 SER A N 1 ATOM 3870 C CA . SER A 1 489 ? -28.178 18.641 -22.722 1.00 58.38 ? 490 SER A CA 1 ATOM 3871 C C . SER A 1 489 ? -29.202 19.698 -22.321 1.00 49.88 ? 490 SER A C 1 ATOM 3872 O O . SER A 1 489 ? -30.403 19.492 -22.507 1.00 46.99 ? 490 SER A O 1 ATOM 3873 C CB . SER A 1 489 ? -27.802 18.834 -24.190 1.00 55.88 ? 490 SER A CB 1 ATOM 3874 O OG . SER A 1 489 ? -27.164 17.681 -24.691 1.00 66.98 ? 490 SER A OG 1 ATOM 3875 N N . LYS A 1 490 ? -28.705 20.810 -21.790 1.00 43.42 ? 491 LYS A N 1 ATOM 3876 C CA . LYS A 1 490 ? -29.497 21.730 -21.056 1.00 49.63 ? 491 LYS A CA 1 ATOM 3877 C C . LYS A 1 490 ? -29.838 22.893 -21.982 1.00 52.23 ? 491 LYS A C 1 ATOM 3878 O O . LYS A 1 490 ? -28.919 23.457 -22.574 1.00 42.75 ? 491 LYS A O 1 ATOM 3879 C CB . LYS A 1 490 ? -28.729 22.227 -19.835 1.00 59.49 ? 491 LYS A CB 1 ATOM 3880 C CG . LYS A 1 490 ? -28.961 21.390 -18.567 1.00 70.87 ? 491 LYS A CG 1 ATOM 3881 C CD . LYS A 1 490 ? -29.270 22.264 -17.335 1.00 82.32 ? 491 LYS A CD 1 ATOM 3882 C CE . LYS A 1 490 ? -28.011 22.778 -16.634 1.00 89.15 ? 491 LYS A CE 1 ATOM 3883 N NZ . LYS A 1 490 ? -27.402 21.751 -15.727 1.00 85.42 ? 491 LYS A NZ 1 ATOM 3884 N N . TRP A 1 491 ? -31.144 23.225 -22.110 1.00 36.05 ? 492 TRP A N 1 ATOM 3885 C CA . TRP A 1 491 ? -31.545 24.414 -22.807 1.00 32.77 ? 492 TRP A CA 1 ATOM 3886 C C . TRP A 1 491 ? -31.209 25.609 -21.938 1.00 32.49 ? 492 TRP A C 1 ATOM 3887 O O . TRP A 1 491 ? -31.816 25.838 -20.944 1.00 34.11 ? 492 TRP A O 1 ATOM 3888 C CB . TRP A 1 491 ? -33.037 24.297 -23.124 1.00 30.91 ? 492 TRP A CB 1 ATOM 3889 C CG . TRP A 1 491 ? -33.686 25.346 -23.993 1.00 29.57 ? 492 TRP A CG 1 ATOM 3890 C CD1 . TRP A 1 491 ? -33.227 26.640 -24.271 1.00 31.99 ? 492 TRP A CD1 1 ATOM 3891 C CD2 . TRP A 1 491 ? -34.997 25.268 -24.536 1.00 27.37 ? 492 TRP A CD2 1 ATOM 3892 N NE1 . TRP A 1 491 ? -34.163 27.313 -25.034 1.00 33.76 ? 492 TRP A NE1 1 ATOM 3893 C CE2 . TRP A 1 491 ? -35.256 26.491 -25.203 1.00 31.91 ? 492 TRP A CE2 1 ATOM 3894 C CE3 . TRP A 1 491 ? -35.956 24.268 -24.568 1.00 30.60 ? 492 TRP A CE3 1 ATOM 3895 C CZ2 . TRP A 1 491 ? -36.453 26.737 -25.884 1.00 30.69 ? 492 TRP A CZ2 1 ATOM 3896 C CZ3 . TRP A 1 491 ? -37.133 24.492 -25.256 1.00 32.62 ? 492 TRP A CZ3 1 ATOM 3897 C CH2 . TRP A 1 491 ? -37.376 25.749 -25.917 1.00 29.22 ? 492 TRP A CH2 1 ATOM 3898 N N . PRO A 1 492 ? -30.209 26.397 -22.304 1.00 37.59 ? 493 PRO A N 1 ATOM 3899 C CA . PRO A 1 492 ? -29.871 27.531 -21.432 1.00 35.81 ? 493 PRO A CA 1 ATOM 3900 C C . PRO A 1 492 ? -30.878 28.699 -21.471 1.00 40.69 ? 493 PRO A C 1 ATOM 3901 O O . PRO A 1 492 ? -31.627 28.875 -22.431 1.00 38.86 ? 493 PRO A O 1 ATOM 3902 C CB . PRO A 1 492 ? -28.509 27.980 -21.956 1.00 37.57 ? 493 PRO A CB 1 ATOM 3903 C CG . PRO A 1 492 ? -28.558 27.628 -23.392 1.00 40.46 ? 493 PRO A CG 1 ATOM 3904 C CD . PRO A 1 492 ? -29.373 26.364 -23.511 1.00 40.07 ? 493 PRO A CD 1 ATOM 3905 N N . LEU A 1 493 ? -30.929 29.432 -20.370 1.00 39.29 ? 494 LEU A N 1 ATOM 3906 C CA . LEU A 1 493 ? -31.650 30.671 -20.289 1.00 39.38 ? 494 LEU A CA 1 ATOM 3907 C C . LEU A 1 493 ? -31.129 31.684 -21.326 1.00 39.36 ? 494 LEU A C 1 ATOM 3908 O O . LEU A 1 493 ? -29.930 31.847 -21.534 1.00 38.73 ? 494 LEU A O 1 ATOM 3909 C CB . LEU A 1 493 ? -31.466 31.279 -18.893 1.00 41.40 ? 494 LEU A CB 1 ATOM 3910 C CG . LEU A 1 493 ? -32.539 31.754 -17.905 1.00 46.58 ? 494 LEU A CG 1 ATOM 3911 C CD1 . LEU A 1 493 ? -33.896 31.089 -17.966 1.00 42.86 ? 494 LEU A CD1 1 ATOM 3912 C CD2 . LEU A 1 493 ? -31.951 31.566 -16.499 1.00 46.24 ? 494 LEU A CD2 1 ATOM 3913 N N . PHE A 1 494 ? -32.060 32.414 -21.926 1.00 37.10 ? 495 PHE A N 1 ATOM 3914 C CA . PHE A 1 494 ? -31.731 33.531 -22.756 1.00 32.79 ? 495 PHE A CA 1 ATOM 3915 C C . PHE A 1 494 ? -31.556 34.708 -21.814 1.00 32.44 ? 495 PHE A C 1 ATOM 3916 O O . PHE A 1 494 ? -32.440 35.016 -21.010 1.00 32.48 ? 495 PHE A O 1 ATOM 3917 C CB . PHE A 1 494 ? -32.900 33.775 -23.729 1.00 33.46 ? 495 PHE A CB 1 ATOM 3918 C CG . PHE A 1 494 ? -32.786 35.064 -24.499 1.00 33.44 ? 495 PHE A CG 1 ATOM 3919 C CD1 . PHE A 1 494 ? -33.102 36.250 -23.908 1.00 30.68 ? 495 PHE A CD1 1 ATOM 3920 C CD2 . PHE A 1 494 ? -32.322 35.078 -25.822 1.00 34.46 ? 495 PHE A CD2 1 ATOM 3921 C CE1 . PHE A 1 494 ? -33.022 37.462 -24.599 1.00 34.86 ? 495 PHE A CE1 1 ATOM 3922 C CE2 . PHE A 1 494 ? -32.238 36.276 -26.527 1.00 35.92 ? 495 PHE A CE2 1 ATOM 3923 C CZ . PHE A 1 494 ? -32.544 37.475 -25.908 1.00 36.62 ? 495 PHE A CZ 1 ATOM 3924 N N . THR A 1 495 ? -30.438 35.389 -21.915 1.00 32.01 ? 496 THR A N 1 ATOM 3925 C CA . THR A 1 495 ? -30.180 36.584 -21.091 1.00 33.92 ? 496 THR A CA 1 ATOM 3926 C C . THR A 1 495 ? -29.842 37.755 -21.979 1.00 34.63 ? 496 THR A C 1 ATOM 3927 O O . THR A 1 495 ? -29.351 37.597 -23.090 1.00 34.47 ? 496 THR A O 1 ATOM 3928 C CB . THR A 1 495 ? -28.987 36.351 -20.141 1.00 36.23 ? 496 THR A CB 1 ATOM 3929 O OG1 . THR A 1 495 ? -27.756 36.166 -20.903 1.00 37.90 ? 496 THR A OG1 1 ATOM 3930 C CG2 . THR A 1 495 ? -29.271 35.084 -19.298 1.00 33.23 ? 496 THR A CG2 1 ATOM 3931 N N . THR A 1 496 ? -30.131 38.930 -21.483 1.00 42.58 ? 497 THR A N 1 ATOM 3932 C CA . THR A 1 496 ? -29.802 40.167 -22.164 1.00 49.56 ? 497 THR A CA 1 ATOM 3933 C C . THR A 1 496 ? -28.381 40.163 -22.674 1.00 52.75 ? 497 THR A C 1 ATOM 3934 O O . THR A 1 496 ? -28.131 40.571 -23.794 1.00 52.50 ? 497 THR A O 1 ATOM 3935 C CB . THR A 1 496 ? -29.924 41.340 -21.179 1.00 51.95 ? 497 THR A CB 1 ATOM 3936 O OG1 . THR A 1 496 ? -31.147 41.215 -20.443 1.00 57.81 ? 497 THR A OG1 1 ATOM 3937 C CG2 . THR A 1 496 ? -29.900 42.630 -21.905 1.00 54.12 ? 497 THR A CG2 1 ATOM 3938 N N . LYS A 1 497 ? -27.454 39.668 -21.856 1.00 52.24 ? 498 LYS A N 1 ATOM 3939 C CA . LYS A 1 497 ? -26.057 39.737 -22.196 1.00 53.20 ? 498 LYS A CA 1 ATOM 3940 C C . LYS A 1 497 ? -25.707 38.738 -23.299 1.00 46.81 ? 498 LYS A C 1 ATOM 3941 O O . LYS A 1 497 ? -25.149 39.101 -24.342 1.00 44.97 ? 498 LYS A O 1 ATOM 3942 C CB . LYS A 1 497 ? -25.195 39.508 -20.941 1.00 58.71 ? 498 LYS A CB 1 ATOM 3943 C CG . LYS A 1 497 ? -23.694 39.648 -21.213 1.00 78.15 ? 498 LYS A CG 1 ATOM 3944 C CD . LYS A 1 497 ? -22.884 40.192 -20.032 1.00 90.25 ? 498 LYS A CD 1 ATOM 3945 C CE . LYS A 1 497 ? -23.118 41.698 -19.833 1.00 97.72 ? 498 LYS A CE 1 ATOM 3946 N NZ . LYS A 1 497 ? -22.190 42.333 -18.850 1.00 98.85 ? 498 LYS A NZ 1 ATOM 3947 N N . GLU A 1 498 ? -26.009 37.470 -23.064 1.00 41.84 ? 499 GLU A N 1 ATOM 3948 C CA . GLU A 1 498 ? -25.463 36.399 -23.916 1.00 42.01 ? 499 GLU A CA 1 ATOM 3949 C C . GLU A 1 498 ? -26.418 35.980 -25.018 1.00 38.25 ? 499 GLU A C 1 ATOM 3950 O O . GLU A 1 498 ? -26.010 35.384 -25.969 1.00 32.26 ? 499 GLU A O 1 ATOM 3951 C CB . GLU A 1 498 ? -25.106 35.189 -23.074 1.00 47.77 ? 499 GLU A CB 1 ATOM 3952 C CG . GLU A 1 498 ? -24.429 35.504 -21.730 1.00 59.83 ? 499 GLU A CG 1 ATOM 3953 C CD . GLU A 1 498 ? -22.970 35.265 -21.794 1.00 65.97 ? 499 GLU A CD 1 ATOM 3954 O OE1 . GLU A 1 498 ? -22.272 36.212 -22.199 1.00 74.92 ? 499 GLU A OE1 1 ATOM 3955 O OE2 . GLU A 1 498 ? -22.548 34.108 -21.498 1.00 83.78 ? 499 GLU A OE2 1 ATOM 3956 N N . GLN A 1 499 ? -27.718 36.218 -24.830 1.00 38.02 ? 500 GLN A N 1 ATOM 3957 C CA . GLN A 1 499 ? -28.709 35.967 -25.868 1.00 40.58 ? 500 GLN A CA 1 ATOM 3958 C C . GLN A 1 499 ? -28.727 34.566 -26.514 1.00 36.75 ? 500 GLN A C 1 ATOM 3959 O O . GLN A 1 499 ? -28.943 34.411 -27.702 1.00 33.27 ? 500 GLN A O 1 ATOM 3960 C CB . GLN A 1 499 ? -28.592 37.079 -26.897 1.00 46.44 ? 500 GLN A CB 1 ATOM 3961 C CG . GLN A 1 499 ? -28.976 38.429 -26.275 1.00 47.41 ? 500 GLN A CG 1 ATOM 3962 C CD . GLN A 1 499 ? -28.696 39.583 -27.203 1.00 46.98 ? 500 GLN A CD 1 ATOM 3963 O OE1 . GLN A 1 499 ? -28.804 39.444 -28.381 1.00 46.84 ? 500 GLN A OE1 1 ATOM 3964 N NE2 . GLN A 1 499 ? -28.270 40.701 -26.658 1.00 49.55 ? 500 GLN A NE2 1 ATOM 3965 N N . LYS A 1 500 ? -28.610 33.536 -25.688 1.00 36.68 ? 501 LYS A N 1 ATOM 3966 C CA . LYS A 1 500 ? -28.547 32.182 -26.193 1.00 34.54 ? 501 LYS A CA 1 ATOM 3967 C C . LYS A 1 500 ? -29.852 31.576 -26.603 1.00 33.38 ? 501 LYS A C 1 ATOM 3968 O O . LYS A 1 500 ? -30.912 31.879 -26.034 1.00 30.27 ? 501 LYS A O 1 ATOM 3969 C CB . LYS A 1 500 ? -27.943 31.274 -25.178 1.00 37.81 ? 501 LYS A CB 1 ATOM 3970 C CG . LYS A 1 500 ? -26.505 31.644 -24.881 1.00 43.02 ? 501 LYS A CG 1 ATOM 3971 C CD . LYS A 1 500 ? -25.985 30.847 -23.691 1.00 47.07 ? 501 LYS A CD 1 ATOM 3972 C CE . LYS A 1 500 ? -24.604 31.380 -23.295 1.00 50.19 ? 501 LYS A CE 1 ATOM 3973 N NZ . LYS A 1 500 ? -23.776 30.316 -22.685 1.00 48.67 ? 501 LYS A NZ 1 ATOM 3974 N N . PHE A 1 501 ? -29.756 30.629 -27.537 1.00 28.00 ? 502 PHE A N 1 ATOM 3975 C CA . PHE A 1 501 ? -30.919 29.917 -27.906 1.00 29.21 ? 502 PHE A CA 1 ATOM 3976 C C . PHE A 1 501 ? -30.481 28.584 -28.431 1.00 31.24 ? 502 PHE A C 1 ATOM 3977 O O . PHE A 1 501 ? -29.302 28.332 -28.614 1.00 32.75 ? 502 PHE A O 1 ATOM 3978 C CB . PHE A 1 501 ? -31.739 30.705 -28.973 1.00 30.16 ? 502 PHE A CB 1 ATOM 3979 C CG . PHE A 1 501 ? -31.069 30.813 -30.329 1.00 25.32 ? 502 PHE A CG 1 ATOM 3980 C CD1 . PHE A 1 501 ? -30.206 31.827 -30.592 1.00 24.21 ? 502 PHE A CD1 1 ATOM 3981 C CD2 . PHE A 1 501 ? -31.353 29.893 -31.330 1.00 27.47 ? 502 PHE A CD2 1 ATOM 3982 C CE1 . PHE A 1 501 ? -29.573 31.919 -31.817 1.00 28.16 ? 502 PHE A CE1 1 ATOM 3983 C CE2 . PHE A 1 501 ? -30.751 29.996 -32.595 1.00 28.87 ? 502 PHE A CE2 1 ATOM 3984 C CZ . PHE A 1 501 ? -29.869 31.024 -32.846 1.00 26.37 ? 502 PHE A CZ 1 ATOM 3985 N N . ILE A 1 502 ? -31.442 27.720 -28.642 1.00 29.27 ? 503 ILE A N 1 ATOM 3986 C CA . ILE A 1 502 ? -31.140 26.438 -29.179 1.00 34.63 ? 503 ILE A CA 1 ATOM 3987 C C . ILE A 1 502 ? -31.939 26.161 -30.449 1.00 35.10 ? 503 ILE A C 1 ATOM 3988 O O . ILE A 1 502 ? -33.019 26.740 -30.668 1.00 32.18 ? 503 ILE A O 1 ATOM 3989 C CB . ILE A 1 502 ? -31.469 25.296 -28.177 1.00 37.83 ? 503 ILE A CB 1 ATOM 3990 C CG1 . ILE A 1 502 ? -32.959 25.275 -27.829 1.00 35.93 ? 503 ILE A CG1 1 ATOM 3991 C CG2 . ILE A 1 502 ? -30.627 25.455 -26.925 1.00 35.71 ? 503 ILE A CG2 1 ATOM 3992 C CD1 . ILE A 1 502 ? -33.489 23.932 -27.469 1.00 37.90 ? 503 ILE A CD1 1 ATOM 3993 N N . ASP A 1 503 ? -31.391 25.257 -31.249 1.00 34.17 ? 504 ASP A N 1 ATOM 3994 C CA . ASP A 1 503 ? -32.040 24.758 -32.416 1.00 38.07 ? 504 ASP A CA 1 ATOM 3995 C C . ASP A 1 503 ? -32.883 23.615 -31.866 1.00 36.02 ? 504 ASP A C 1 ATOM 3996 O O . ASP A 1 503 ? -32.517 22.990 -30.886 1.00 41.56 ? 504 ASP A O 1 ATOM 3997 C CB . ASP A 1 503 ? -31.058 24.201 -33.475 1.00 41.37 ? 504 ASP A CB 1 ATOM 3998 C CG . ASP A 1 503 ? -30.140 25.270 -34.119 1.00 44.49 ? 504 ASP A CG 1 ATOM 3999 O OD1 . ASP A 1 503 ? -30.489 26.444 -34.269 1.00 49.96 ? 504 ASP A OD1 1 ATOM 4000 O OD2 . ASP A 1 503 ? -29.009 24.927 -34.502 1.00 54.58 ? 504 ASP A OD2 1 ATOM 4001 N N . LEU A 1 504 ? -33.977 23.348 -32.555 1.00 34.02 ? 505 LEU A N 1 ATOM 4002 C CA . LEU A 1 504 ? -34.865 22.283 -32.285 1.00 36.53 ? 505 LEU A CA 1 ATOM 4003 C C . LEU A 1 504 ? -34.972 21.424 -33.563 1.00 40.16 ? 505 LEU A C 1 ATOM 4004 O O . LEU A 1 504 ? -35.652 21.761 -34.510 1.00 39.66 ? 505 LEU A O 1 ATOM 4005 C CB . LEU A 1 504 ? -36.199 22.906 -31.869 1.00 38.88 ? 505 LEU A CB 1 ATOM 4006 C CG . LEU A 1 504 ? -36.906 22.454 -30.587 1.00 42.29 ? 505 LEU A CG 1 ATOM 4007 C CD1 . LEU A 1 504 ? -36.011 22.144 -29.393 1.00 39.04 ? 505 LEU A CD1 1 ATOM 4008 C CD2 . LEU A 1 504 ? -37.923 23.513 -30.225 1.00 41.01 ? 505 LEU A CD2 1 ATOM 4009 N N . ASN A 1 505 ? -34.252 20.307 -33.595 1.00 44.57 ? 506 ASN A N 1 ATOM 4010 C CA . ASN A 1 505 ? -34.319 19.389 -34.699 1.00 43.04 ? 506 ASN A CA 1 ATOM 4011 C C . ASN A 1 505 ? -33.940 17.971 -34.236 1.00 44.61 ? 506 ASN A C 1 ATOM 4012 O O . ASN A 1 505 ? -33.859 17.721 -33.073 1.00 47.21 ? 506 ASN A O 1 ATOM 4013 C CB . ASN A 1 505 ? -33.414 19.904 -35.821 1.00 38.90 ? 506 ASN A CB 1 ATOM 4014 C CG . ASN A 1 505 ? -32.016 20.108 -35.358 1.00 37.86 ? 506 ASN A CG 1 ATOM 4015 O OD1 . ASN A 1 505 ? -31.534 19.296 -34.618 1.00 42.13 ? 506 ASN A OD1 1 ATOM 4016 N ND2 . ASN A 1 505 ? -31.371 21.227 -35.730 1.00 37.21 ? 506 ASN A ND2 1 ATOM 4017 N N . THR A 1 506 ? -33.736 17.056 -35.164 1.00 44.99 ? 507 THR A N 1 ATOM 4018 C CA . THR A 1 506 ? -33.398 15.671 -34.866 1.00 48.34 ? 507 THR A CA 1 ATOM 4019 C C . THR A 1 506 ? -31.927 15.433 -34.497 1.00 49.84 ? 507 THR A C 1 ATOM 4020 O O . THR A 1 506 ? -31.577 14.356 -34.054 1.00 55.76 ? 507 THR A O 1 ATOM 4021 C CB . THR A 1 506 ? -33.734 14.801 -36.081 1.00 44.73 ? 507 THR A CB 1 ATOM 4022 O OG1 . THR A 1 506 ? -33.119 15.384 -37.253 1.00 47.13 ? 507 THR A OG1 1 ATOM 4023 C CG2 . THR A 1 506 ? -35.206 14.747 -36.260 1.00 43.72 ? 507 THR A CG2 1 ATOM 4024 N N . GLU A 1 507 ? -31.086 16.437 -34.650 1.00 52.07 ? 508 GLU A N 1 ATOM 4025 C CA . GLU A 1 507 ? -29.663 16.344 -34.343 1.00 52.42 ? 508 GLU A CA 1 ATOM 4026 C C . GLU A 1 507 ? -29.388 16.779 -32.897 1.00 53.52 ? 508 GLU A C 1 ATOM 4027 O O . GLU A 1 507 ? -30.218 17.425 -32.288 1.00 49.75 ? 508 GLU A O 1 ATOM 4028 C CB . GLU A 1 507 ? -28.866 17.241 -35.317 1.00 53.35 ? 508 GLU A CB 1 ATOM 4029 C CG . GLU A 1 507 ? -28.999 16.862 -36.795 1.00 66.24 ? 508 GLU A CG 1 ATOM 4030 C CD . GLU A 1 507 ? -28.696 18.067 -37.696 1.00 92.74 ? 508 GLU A CD 1 ATOM 4031 O OE1 . GLU A 1 507 ? -27.615 18.697 -37.527 1.00 102.32 ? 508 GLU A OE1 1 ATOM 4032 O OE2 . GLU A 1 507 ? -29.546 18.416 -38.553 1.00 100.68 ? 508 GLU A OE2 1 ATOM 4033 N N . PRO A 1 508 ? -28.208 16.433 -32.345 1.00 61.96 ? 509 PRO A N 1 ATOM 4034 C CA . PRO A 1 508 ? -27.944 16.830 -30.961 1.00 67.01 ? 509 PRO A CA 1 ATOM 4035 C C . PRO A 1 508 ? -27.994 18.347 -30.750 1.00 62.95 ? 509 PRO A C 1 ATOM 4036 O O . PRO A 1 508 ? -27.457 19.109 -31.557 1.00 58.33 ? 509 PRO A O 1 ATOM 4037 C CB . PRO A 1 508 ? -26.523 16.274 -30.674 1.00 65.18 ? 509 PRO A CB 1 ATOM 4038 C CG . PRO A 1 508 ? -25.965 15.874 -32.005 1.00 66.16 ? 509 PRO A CG 1 ATOM 4039 C CD . PRO A 1 508 ? -27.154 15.548 -32.871 1.00 61.71 ? 509 PRO A CD 1 ATOM 4040 N N . MET A 1 509 ? -28.646 18.756 -29.658 1.00 61.72 ? 510 MET A N 1 ATOM 4041 C CA . MET A 1 509 ? -28.867 20.149 -29.346 1.00 60.53 ? 510 MET A CA 1 ATOM 4042 C C . MET A 1 509 ? -27.580 20.917 -29.577 1.00 60.46 ? 510 MET A C 1 ATOM 4043 O O . MET A 1 509 ? -26.481 20.443 -29.296 1.00 63.95 ? 510 MET A O 1 ATOM 4044 C CB . MET A 1 509 ? -29.345 20.315 -27.911 1.00 63.86 ? 510 MET A CB 1 ATOM 4045 C CG . MET A 1 509 ? -29.548 21.758 -27.468 1.00 67.09 ? 510 MET A CG 1 ATOM 4046 S SD . MET A 1 509 ? -29.517 21.937 -25.670 1.00 63.42 ? 510 MET A SD 1 ATOM 4047 C CE . MET A 1 509 ? -31.017 21.021 -25.291 1.00 60.77 ? 510 MET A CE 1 ATOM 4048 N N . LYS A 1 510 ? -27.736 22.082 -30.179 1.00 60.99 ? 511 LYS A N 1 ATOM 4049 C CA . LYS A 1 510 ? -26.652 23.008 -30.393 1.00 55.72 ? 511 LYS A CA 1 ATOM 4050 C C . LYS A 1 510 ? -27.226 24.352 -29.902 1.00 51.97 ? 511 LYS A C 1 ATOM 4051 O O . LYS A 1 510 ? -28.399 24.687 -30.169 1.00 49.26 ? 511 LYS A O 1 ATOM 4052 C CB . LYS A 1 510 ? -26.261 23.004 -31.873 1.00 61.72 ? 511 LYS A CB 1 ATOM 4053 C CG . LYS A 1 510 ? -24.785 23.255 -32.132 1.00 80.42 ? 511 LYS A CG 1 ATOM 4054 C CD . LYS A 1 510 ? -24.293 22.683 -33.472 1.00 91.47 ? 511 LYS A CD 1 ATOM 4055 C CE . LYS A 1 510 ? -22.773 22.467 -33.473 1.00 97.43 ? 511 LYS A CE 1 ATOM 4056 N NZ . LYS A 1 510 ? -22.143 22.810 -34.783 1.00 99.97 ? 511 LYS A NZ 1 ATOM 4057 N N . VAL A 1 511 ? -26.419 25.033 -29.106 1.00 41.23 ? 512 VAL A N 1 ATOM 4058 C CA . VAL A 1 511 ? -26.655 26.344 -28.585 1.00 40.83 ? 512 VAL A CA 1 ATOM 4059 C C . VAL A 1 511 ? -25.969 27.360 -29.456 1.00 41.85 ? 512 VAL A C 1 ATOM 4060 O O . VAL A 1 511 ? -24.796 27.184 -29.827 1.00 40.66 ? 512 VAL A O 1 ATOM 4061 C CB . VAL A 1 511 ? -26.030 26.485 -27.155 1.00 43.65 ? 512 VAL A CB 1 ATOM 4062 C CG1 . VAL A 1 511 ? -26.169 27.918 -26.592 1.00 39.25 ? 512 VAL A CG1 1 ATOM 4063 C CG2 . VAL A 1 511 ? -26.658 25.435 -26.204 1.00 43.75 ? 512 VAL A CG2 1 ATOM 4064 N N . HIS A 1 512 ? -26.682 28.455 -29.729 1.00 39.33 ? 513 HIS A N 1 ATOM 4065 C CA . HIS A 1 512 ? -26.146 29.593 -30.476 1.00 38.51 ? 513 HIS A CA 1 ATOM 4066 C C . HIS A 1 512 ? -26.455 30.912 -29.773 1.00 40.12 ? 513 HIS A C 1 ATOM 4067 O O . HIS A 1 512 ? -27.127 30.947 -28.729 1.00 37.05 ? 513 HIS A O 1 ATOM 4068 C CB . HIS A 1 512 ? -26.820 29.659 -31.852 1.00 40.02 ? 513 HIS A CB 1 ATOM 4069 C CG . HIS A 1 512 ? -26.792 28.387 -32.623 1.00 38.42 ? 513 HIS A CG 1 ATOM 4070 N ND1 . HIS A 1 512 ? -25.674 27.964 -33.312 1.00 43.20 ? 513 HIS A ND1 1 ATOM 4071 C CD2 . HIS A 1 512 ? -27.749 27.459 -32.846 1.00 41.24 ? 513 HIS A CD2 1 ATOM 4072 C CE1 . HIS A 1 512 ? -25.942 26.825 -33.929 1.00 42.16 ? 513 HIS A CE1 1 ATOM 4073 N NE2 . HIS A 1 512 ? -27.190 26.488 -33.655 1.00 42.57 ? 513 HIS A NE2 1 ATOM 4074 N N . GLN A 1 513 ? -26.057 32.013 -30.398 1.00 42.77 ? 514 GLN A N 1 ATOM 4075 C CA . GLN A 1 513 ? -26.344 33.332 -29.845 1.00 43.55 ? 514 GLN A CA 1 ATOM 4076 C C . GLN A 1 513 ? -26.850 34.309 -30.878 1.00 38.66 ? 514 GLN A C 1 ATOM 4077 O O . GLN A 1 513 ? -26.529 34.191 -32.012 1.00 35.94 ? 514 GLN A O 1 ATOM 4078 C CB . GLN A 1 513 ? -25.069 33.895 -29.204 1.00 43.54 ? 514 GLN A CB 1 ATOM 4079 C CG . GLN A 1 513 ? -24.638 33.032 -28.009 1.00 51.22 ? 514 GLN A CG 1 ATOM 4080 C CD . GLN A 1 513 ? -23.365 33.507 -27.363 1.00 43.90 ? 514 GLN A CD 1 ATOM 4081 O OE1 . GLN A 1 513 ? -22.302 32.992 -27.644 1.00 51.75 ? 514 GLN A OE1 1 ATOM 4082 N NE2 . GLN A 1 513 ? -23.467 34.540 -26.556 1.00 45.25 ? 514 GLN A NE2 1 ATOM 4083 N N . ARG A 1 514 ? -27.650 35.275 -30.445 1.00 38.61 ? 515 ARG A N 1 ATOM 4084 C CA . ARG A 1 514 ? -27.977 36.432 -31.246 1.00 41.66 ? 515 ARG A CA 1 ATOM 4085 C C . ARG A 1 514 ? -28.679 36.013 -32.559 1.00 39.30 ? 515 ARG A C 1 ATOM 4086 O O . ARG A 1 514 ? -28.157 36.186 -33.627 1.00 35.38 ? 515 ARG A O 1 ATOM 4087 C CB . ARG A 1 514 ? -26.694 37.227 -31.478 1.00 43.78 ? 515 ARG A CB 1 ATOM 4088 C CG . ARG A 1 514 ? -26.274 38.037 -30.261 1.00 50.08 ? 515 ARG A CG 1 ATOM 4089 C CD . ARG A 1 514 ? -24.930 38.707 -30.417 1.00 51.89 ? 515 ARG A CD 1 ATOM 4090 N NE . ARG A 1 514 ? -24.721 39.749 -29.423 1.00 58.26 ? 515 ARG A NE 1 ATOM 4091 C CZ . ARG A 1 514 ? -23.912 40.821 -29.564 1.00 77.39 ? 515 ARG A CZ 1 ATOM 4092 N NH1 . ARG A 1 514 ? -23.192 41.063 -30.681 1.00 87.12 ? 515 ARG A NH1 1 ATOM 4093 N NH2 . ARG A 1 514 ? -23.801 41.687 -28.564 1.00 77.01 ? 515 ARG A NH2 1 ATOM 4094 N N . LEU A 1 515 ? -29.854 35.416 -32.412 1.00 36.46 ? 516 LEU A N 1 ATOM 4095 C CA . LEU A 1 515 ? -30.673 34.897 -33.496 1.00 38.18 ? 516 LEU A CA 1 ATOM 4096 C C . LEU A 1 515 ? -31.025 36.006 -34.519 1.00 37.39 ? 516 LEU A C 1 ATOM 4097 O O . LEU A 1 515 ? -31.736 36.980 -34.184 1.00 30.12 ? 516 LEU A O 1 ATOM 4098 C CB . LEU A 1 515 ? -31.968 34.306 -32.885 1.00 40.34 ? 516 LEU A CB 1 ATOM 4099 C CG . LEU A 1 515 ? -33.174 33.884 -33.723 1.00 40.80 ? 516 LEU A CG 1 ATOM 4100 C CD1 . LEU A 1 515 ? -32.698 33.151 -34.916 1.00 44.16 ? 516 LEU A CD1 1 ATOM 4101 C CD2 . LEU A 1 515 ? -34.112 32.972 -32.908 1.00 42.32 ? 516 LEU A CD2 1 ATOM 4102 N N . ARG A 1 516 ? -30.507 35.853 -35.738 1.00 32.65 ? 517 ARG A N 1 ATOM 4103 C CA . ARG A 1 516 ? -30.720 36.796 -36.856 1.00 33.24 ? 517 ARG A CA 1 ATOM 4104 C C . ARG A 1 516 ? -30.449 38.201 -36.535 1.00 31.43 ? 517 ARG A C 1 ATOM 4105 O O . ARG A 1 516 ? -31.166 39.060 -36.991 1.00 34.92 ? 517 ARG A O 1 ATOM 4106 C CB . ARG A 1 516 ? -32.115 36.585 -37.522 1.00 37.64 ? 517 ARG A CB 1 ATOM 4107 C CG . ARG A 1 516 ? -31.955 35.283 -38.336 1.00 44.96 ? 517 ARG A CG 1 ATOM 4108 C CD . ARG A 1 516 ? -33.047 34.804 -39.283 1.00 49.08 ? 517 ARG A CD 1 ATOM 4109 N NE . ARG A 1 516 ? -33.115 35.521 -40.544 1.00 54.87 ? 517 ARG A NE 1 ATOM 4110 C CZ . ARG A 1 516 ? -32.281 35.386 -41.591 1.00 55.25 ? 517 ARG A CZ 1 ATOM 4111 N NH1 . ARG A 1 516 ? -31.262 34.561 -41.530 1.00 55.69 ? 517 ARG A NH1 1 ATOM 4112 N NH2 . ARG A 1 516 ? -32.454 36.094 -42.725 1.00 45.24 ? 517 ARG A NH2 1 ATOM 4113 N N . VAL A 1 517 ? -29.423 38.474 -35.716 1.00 33.06 ? 518 VAL A N 1 ATOM 4114 C CA . VAL A 1 517 ? -29.269 39.844 -35.243 1.00 30.37 ? 518 VAL A CA 1 ATOM 4115 C C . VAL A 1 517 ? -29.030 40.800 -36.429 1.00 29.07 ? 518 VAL A C 1 ATOM 4116 O O . VAL A 1 517 ? -29.329 41.966 -36.307 1.00 30.84 ? 518 VAL A O 1 ATOM 4117 C CB . VAL A 1 517 ? -27.950 40.127 -34.504 1.00 32.58 ? 518 VAL A CB 1 ATOM 4118 C CG1 . VAL A 1 517 ? -28.069 41.069 -33.322 1.00 29.71 ? 518 VAL A CG1 1 ATOM 4119 C CG2 . VAL A 1 517 ? -27.009 38.982 -34.496 1.00 29.03 ? 518 VAL A CG2 1 ATOM 4120 N N . GLN A 1 518 ? -28.216 40.371 -37.415 1.00 28.95 ? 519 GLN A N 1 ATOM 4121 C CA . GLN A 1 518 ? -27.810 41.262 -38.520 1.00 31.96 ? 519 GLN A CA 1 ATOM 4122 C C . GLN A 1 518 ? -29.120 41.781 -39.184 1.00 29.95 ? 519 GLN A C 1 ATOM 4123 O O . GLN A 1 518 ? -29.347 42.944 -39.227 1.00 29.18 ? 519 GLN A O 1 ATOM 4124 C CB . GLN A 1 518 ? -26.910 40.473 -39.548 1.00 32.66 ? 519 GLN A CB 1 ATOM 4125 C CG . GLN A 1 518 ? -26.041 41.392 -40.431 1.00 35.30 ? 519 GLN A CG 1 ATOM 4126 C CD . GLN A 1 518 ? -25.030 42.200 -39.619 1.00 40.01 ? 519 GLN A CD 1 ATOM 4127 O OE1 . GLN A 1 518 ? -24.501 41.716 -38.604 1.00 45.12 ? 519 GLN A OE1 1 ATOM 4128 N NE2 . GLN A 1 518 ? -24.822 43.456 -39.995 1.00 38.62 ? 519 GLN A NE2 1 ATOM 4129 N N . MET A 1 519 ? -30.019 40.876 -39.592 1.00 25.27 ? 520 MET A N 1 ATOM 4130 C CA . MET A 1 519 ? -31.250 41.277 -40.236 1.00 29.45 ? 520 MET A CA 1 ATOM 4131 C C . MET A 1 519 ? -32.178 42.012 -39.270 1.00 29.80 ? 520 MET A C 1 ATOM 4132 O O . MET A 1 519 ? -32.835 42.975 -39.664 1.00 30.96 ? 520 MET A O 1 ATOM 4133 C CB . MET A 1 519 ? -31.940 40.065 -40.894 1.00 31.34 ? 520 MET A CB 1 ATOM 4134 C CG . MET A 1 519 ? -31.185 39.472 -42.106 1.00 37.57 ? 520 MET A CG 1 ATOM 4135 S SD . MET A 1 519 ? -30.605 40.718 -43.347 1.00 44.43 ? 520 MET A SD 1 ATOM 4136 C CE . MET A 1 519 ? -28.842 40.818 -43.012 1.00 52.60 ? 520 MET A CE 1 ATOM 4137 N N . CYS A 1 520 ? -32.187 41.647 -37.984 1.00 26.66 ? 521 CYS A N 1 ATOM 4138 C CA . CYS A 1 520 ? -33.162 42.274 -37.083 1.00 25.40 ? 521 CYS A CA 1 ATOM 4139 C C . CYS A 1 520 ? -32.680 43.601 -36.673 1.00 23.64 ? 521 CYS A C 1 ATOM 4140 O O . CYS A 1 520 ? -33.527 44.463 -36.386 1.00 23.68 ? 521 CYS A O 1 ATOM 4141 C CB . CYS A 1 520 ? -33.540 41.423 -35.887 1.00 26.95 ? 521 CYS A CB 1 ATOM 4142 S SG . CYS A 1 520 ? -34.319 39.891 -36.405 1.00 29.11 ? 521 CYS A SG 1 ATOM 4143 N N . VAL A 1 521 ? -31.364 43.858 -36.680 1.00 23.58 ? 522 VAL A N 1 ATOM 4144 C CA . VAL A 1 521 ? -30.942 45.279 -36.478 1.00 24.93 ? 522 VAL A CA 1 ATOM 4145 C C . VAL A 1 521 ? -31.446 46.113 -37.679 1.00 27.91 ? 522 VAL A C 1 ATOM 4146 O O . VAL A 1 521 ? -31.861 47.245 -37.553 1.00 25.55 ? 522 VAL A O 1 ATOM 4147 C CB . VAL A 1 521 ? -29.411 45.458 -36.398 1.00 29.74 ? 522 VAL A CB 1 ATOM 4148 C CG1 . VAL A 1 521 ? -28.996 46.963 -36.481 1.00 27.56 ? 522 VAL A CG1 1 ATOM 4149 C CG2 . VAL A 1 521 ? -28.856 44.875 -35.107 1.00 29.17 ? 522 VAL A CG2 1 ATOM 4150 N N . PHE A 1 522 ? -31.429 45.530 -38.879 1.00 29.83 ? 523 PHE A N 1 ATOM 4151 C CA . PHE A 1 522 ? -32.047 46.230 -39.995 1.00 28.79 ? 523 PHE A CA 1 ATOM 4152 C C . PHE A 1 522 ? -33.546 46.520 -39.800 1.00 28.07 ? 523 PHE A C 1 ATOM 4153 O O . PHE A 1 522 ? -34.003 47.681 -39.936 1.00 26.40 ? 523 PHE A O 1 ATOM 4154 C CB . PHE A 1 522 ? -31.808 45.479 -41.305 1.00 26.97 ? 523 PHE A CB 1 ATOM 4155 C CG . PHE A 1 522 ? -32.513 46.075 -42.437 1.00 25.91 ? 523 PHE A CG 1 ATOM 4156 C CD1 . PHE A 1 522 ? -32.004 47.197 -43.092 1.00 28.42 ? 523 PHE A CD1 1 ATOM 4157 C CD2 . PHE A 1 522 ? -33.683 45.553 -42.843 1.00 24.32 ? 523 PHE A CD2 1 ATOM 4158 C CE1 . PHE A 1 522 ? -32.651 47.744 -44.187 1.00 25.03 ? 523 PHE A CE1 1 ATOM 4159 C CE2 . PHE A 1 522 ? -34.357 46.128 -43.876 1.00 26.12 ? 523 PHE A CE2 1 ATOM 4160 C CZ . PHE A 1 522 ? -33.815 47.191 -44.576 1.00 27.67 ? 523 PHE A CZ 1 ATOM 4161 N N . TRP A 1 523 ? -34.316 45.483 -39.527 1.00 27.11 ? 524 TRP A N 1 ATOM 4162 C CA . TRP A 1 523 ? -35.761 45.687 -39.364 1.00 28.63 ? 524 TRP A CA 1 ATOM 4163 C C . TRP A 1 523 ? -36.169 46.396 -38.104 1.00 28.49 ? 524 TRP A C 1 ATOM 4164 O O . TRP A 1 523 ? -37.082 47.175 -38.136 1.00 30.93 ? 524 TRP A O 1 ATOM 4165 C CB . TRP A 1 523 ? -36.516 44.382 -39.397 1.00 27.56 ? 524 TRP A CB 1 ATOM 4166 C CG . TRP A 1 523 ? -36.416 43.714 -40.695 1.00 26.06 ? 524 TRP A CG 1 ATOM 4167 C CD1 . TRP A 1 523 ? -35.584 42.706 -41.015 1.00 26.80 ? 524 TRP A CD1 1 ATOM 4168 C CD2 . TRP A 1 523 ? -37.164 44.005 -41.865 1.00 24.58 ? 524 TRP A CD2 1 ATOM 4169 N NE1 . TRP A 1 523 ? -35.775 42.308 -42.291 1.00 26.43 ? 524 TRP A NE1 1 ATOM 4170 C CE2 . TRP A 1 523 ? -36.713 43.125 -42.868 1.00 28.00 ? 524 TRP A CE2 1 ATOM 4171 C CE3 . TRP A 1 523 ? -38.123 44.943 -42.186 1.00 24.56 ? 524 TRP A CE3 1 ATOM 4172 C CZ2 . TRP A 1 523 ? -37.230 43.136 -44.171 1.00 24.65 ? 524 TRP A CZ2 1 ATOM 4173 C CZ3 . TRP A 1 523 ? -38.660 44.955 -43.505 1.00 26.16 ? 524 TRP A CZ3 1 ATOM 4174 C CH2 . TRP A 1 523 ? -38.207 44.053 -44.459 1.00 24.50 ? 524 TRP A CH2 1 ATOM 4175 N N . ASN A 1 524 ? -35.459 46.214 -37.013 1.00 32.25 ? 525 ASN A N 1 ATOM 4176 C CA . ASN A 1 524 ? -35.884 46.842 -35.716 1.00 30.97 ? 525 ASN A CA 1 ATOM 4177 C C . ASN A 1 524 ? -35.286 48.190 -35.447 1.00 31.39 ? 525 ASN A C 1 ATOM 4178 O O . ASN A 1 524 ? -35.827 48.918 -34.716 1.00 30.56 ? 525 ASN A O 1 ATOM 4179 C CB . ASN A 1 524 ? -35.622 45.913 -34.551 1.00 26.41 ? 525 ASN A CB 1 ATOM 4180 C CG . ASN A 1 524 ? -36.400 44.649 -34.699 1.00 29.41 ? 525 ASN A CG 1 ATOM 4181 O OD1 . ASN A 1 524 ? -37.343 44.617 -35.444 1.00 34.07 ? 525 ASN A OD1 1 ATOM 4182 N ND2 . ASN A 1 524 ? -35.972 43.600 -34.094 1.00 29.93 ? 525 ASN A ND2 1 ATOM 4183 N N . GLN A 1 525 ? -34.187 48.553 -36.051 1.00 35.33 ? 526 GLN A N 1 ATOM 4184 C CA . GLN A 1 525 ? -33.583 49.824 -35.748 1.00 33.40 ? 526 GLN A CA 1 ATOM 4185 C C . GLN A 1 525 ? -33.421 50.697 -36.997 1.00 34.71 ? 526 GLN A C 1 ATOM 4186 O O . GLN A 1 525 ? -33.850 51.839 -36.978 1.00 30.60 ? 526 GLN A O 1 ATOM 4187 C CB . GLN A 1 525 ? -32.242 49.577 -35.123 1.00 41.25 ? 526 GLN A CB 1 ATOM 4188 C CG . GLN A 1 525 ? -32.253 48.952 -33.716 1.00 55.23 ? 526 GLN A CG 1 ATOM 4189 C CD . GLN A 1 525 ? -30.828 48.982 -33.083 1.00 70.52 ? 526 GLN A CD 1 ATOM 4190 O OE1 . GLN A 1 525 ? -30.112 50.012 -33.134 1.00 68.62 ? 526 GLN A OE1 1 ATOM 4191 N NE2 . GLN A 1 525 ? -30.394 47.837 -32.533 1.00 70.29 ? 526 GLN A NE2 1 ATOM 4192 N N . PHE A 1 526 ? -32.809 50.175 -38.086 1.00 31.69 ? 527 PHE A N 1 ATOM 4193 C CA . PHE A 1 526 ? -32.468 51.035 -39.210 1.00 29.47 ? 527 PHE A CA 1 ATOM 4194 C C . PHE A 1 526 ? -33.686 51.411 -40.036 1.00 25.73 ? 527 PHE A C 1 ATOM 4195 O O . PHE A 1 526 ? -34.027 52.592 -40.215 1.00 29.06 ? 527 PHE A O 1 ATOM 4196 C CB . PHE A 1 526 ? -31.313 50.429 -40.074 1.00 28.99 ? 527 PHE A CB 1 ATOM 4197 C CG . PHE A 1 526 ? -30.975 51.272 -41.238 1.00 29.13 ? 527 PHE A CG 1 ATOM 4198 C CD1 . PHE A 1 526 ? -30.277 52.452 -41.066 1.00 33.22 ? 527 PHE A CD1 1 ATOM 4199 C CD2 . PHE A 1 526 ? -31.426 50.949 -42.508 1.00 31.49 ? 527 PHE A CD2 1 ATOM 4200 C CE1 . PHE A 1 526 ? -30.030 53.315 -42.131 1.00 30.49 ? 527 PHE A CE1 1 ATOM 4201 C CE2 . PHE A 1 526 ? -31.159 51.774 -43.583 1.00 33.05 ? 527 PHE A CE2 1 ATOM 4202 C CZ . PHE A 1 526 ? -30.453 52.961 -43.393 1.00 33.31 ? 527 PHE A CZ 1 ATOM 4203 N N . LEU A 1 527 ? -34.381 50.424 -40.554 1.00 26.99 ? 528 LEU A N 1 ATOM 4204 C CA . LEU A 1 527 ? -35.478 50.731 -41.479 1.00 26.60 ? 528 LEU A CA 1 ATOM 4205 C C . LEU A 1 527 ? -36.540 51.666 -40.857 1.00 30.59 ? 528 LEU A C 1 ATOM 4206 O O . LEU A 1 527 ? -37.079 52.551 -41.528 1.00 34.09 ? 528 LEU A O 1 ATOM 4207 C CB . LEU A 1 527 ? -36.135 49.440 -41.965 1.00 25.67 ? 528 LEU A CB 1 ATOM 4208 C CG . LEU A 1 527 ? -37.263 49.666 -42.945 1.00 28.82 ? 528 LEU A CG 1 ATOM 4209 C CD1 . LEU A 1 527 ? -36.753 50.510 -44.175 1.00 30.80 ? 528 LEU A CD1 1 ATOM 4210 C CD2 . LEU A 1 527 ? -37.883 48.333 -43.380 1.00 30.72 ? 528 LEU A CD2 1 ATOM 4211 N N . PRO A 1 528 ? -36.898 51.450 -39.586 1.00 31.97 ? 529 PRO A N 1 ATOM 4212 C CA . PRO A 1 528 ? -37.871 52.386 -39.041 1.00 35.65 ? 529 PRO A CA 1 ATOM 4213 C C . PRO A 1 528 ? -37.310 53.788 -38.839 1.00 33.90 ? 529 PRO A C 1 ATOM 4214 O O . PRO A 1 528 ? -38.031 54.772 -39.067 1.00 37.03 ? 529 PRO A O 1 ATOM 4215 C CB . PRO A 1 528 ? -38.287 51.728 -37.696 1.00 36.10 ? 529 PRO A CB 1 ATOM 4216 C CG . PRO A 1 528 ? -37.931 50.290 -37.853 1.00 37.35 ? 529 PRO A CG 1 ATOM 4217 C CD . PRO A 1 528 ? -36.609 50.374 -38.628 1.00 34.11 ? 529 PRO A CD 1 ATOM 4218 N N . LYS A 1 529 ? -36.026 53.908 -38.520 1.00 37.96 ? 530 LYS A N 1 ATOM 4219 C CA . LYS A 1 529 ? -35.378 55.240 -38.562 1.00 40.48 ? 530 LYS A CA 1 ATOM 4220 C C . LYS A 1 529 ? -35.439 55.830 -39.985 1.00 44.77 ? 530 LYS A C 1 ATOM 4221 O O . LYS A 1 529 ? -35.679 57.012 -40.166 1.00 42.12 ? 530 LYS A O 1 ATOM 4222 C CB . LYS A 1 529 ? -33.962 55.137 -38.120 1.00 48.36 ? 530 LYS A CB 1 ATOM 4223 C CG . LYS A 1 529 ? -33.630 56.099 -37.029 1.00 58.80 ? 530 LYS A CG 1 ATOM 4224 C CD . LYS A 1 529 ? -32.127 56.142 -36.726 1.00 69.88 ? 530 LYS A CD 1 ATOM 4225 C CE . LYS A 1 529 ? -31.642 57.608 -36.752 1.00 70.22 ? 530 LYS A CE 1 ATOM 4226 N NZ . LYS A 1 529 ? -30.363 57.829 -36.042 1.00 69.16 ? 530 LYS A NZ 1 ATOM 4227 N N . LEU A 1 530 ? -35.275 54.997 -41.010 1.00 42.11 ? 531 LEU A N 1 ATOM 4228 C CA . LEU A 1 530 ? -35.227 55.534 -42.368 1.00 39.49 ? 531 LEU A CA 1 ATOM 4229 C C . LEU A 1 530 ? -36.600 56.030 -42.780 1.00 42.90 ? 531 LEU A C 1 ATOM 4230 O O . LEU A 1 530 ? -36.743 57.144 -43.333 1.00 38.24 ? 531 LEU A O 1 ATOM 4231 C CB . LEU A 1 530 ? -34.644 54.488 -43.335 1.00 35.36 ? 531 LEU A CB 1 ATOM 4232 C CG . LEU A 1 530 ? -34.582 54.685 -44.853 1.00 34.99 ? 531 LEU A CG 1 ATOM 4233 C CD1 . LEU A 1 530 ? -33.606 53.703 -45.504 1.00 34.09 ? 531 LEU A CD1 1 ATOM 4234 C CD2 . LEU A 1 530 ? -35.976 54.478 -45.452 1.00 36.25 ? 531 LEU A CD2 1 ATOM 4235 N N . LEU A 1 531 ? -37.618 55.221 -42.521 1.00 40.68 ? 532 LEU A N 1 ATOM 4236 C CA . LEU A 1 531 ? -39.002 55.631 -42.869 1.00 43.76 ? 532 LEU A CA 1 ATOM 4237 C C . LEU A 1 531 ? -39.506 56.803 -41.999 1.00 40.77 ? 532 LEU A C 1 ATOM 4238 O O . LEU A 1 531 ? -40.242 57.603 -42.489 1.00 41.70 ? 532 LEU A O 1 ATOM 4239 C CB . LEU A 1 531 ? -40.021 54.461 -42.828 1.00 40.54 ? 532 LEU A CB 1 ATOM 4240 C CG . LEU A 1 531 ? -39.716 53.213 -43.657 1.00 41.70 ? 532 LEU A CG 1 ATOM 4241 C CD1 . LEU A 1 531 ? -40.479 51.996 -43.125 1.00 43.34 ? 532 LEU A CD1 1 ATOM 4242 C CD2 . LEU A 1 531 ? -39.957 53.439 -45.141 1.00 39.64 ? 532 LEU A CD2 1 ATOM 4243 N N . ASN A 1 532 ? -39.107 56.930 -40.740 1.00 47.83 ? 533 ASN A N 1 ATOM 4244 C CA . ASN A 1 532 ? -39.461 58.159 -39.982 1.00 56.31 ? 533 ASN A CA 1 ATOM 4245 C C . ASN A 1 532 ? -38.827 59.413 -40.580 1.00 53.16 ? 533 ASN A C 1 ATOM 4246 O O . ASN A 1 532 ? -39.387 60.470 -40.483 1.00 46.05 ? 533 ASN A O 1 ATOM 4247 C CB . ASN A 1 532 ? -39.042 58.104 -38.487 1.00 58.33 ? 533 ASN A CB 1 ATOM 4248 C CG . ASN A 1 532 ? -39.829 59.075 -37.611 1.00 61.56 ? 533 ASN A CG 1 ATOM 4249 O OD1 . ASN A 1 532 ? -41.025 59.262 -37.796 1.00 70.75 ? 533 ASN A OD1 1 ATOM 4250 N ND2 . ASN A 1 532 ? -39.169 59.667 -36.633 1.00 66.23 ? 533 ASN A ND2 1 ATOM 4251 N N . ALA A 1 533 ? -37.637 59.312 -41.139 1.00 51.62 ? 534 ALA A N 1 ATOM 4252 C CA . ALA A 1 533 ? -36.939 60.512 -41.526 1.00 58.74 ? 534 ALA A CA 1 ATOM 4253 C C . ALA A 1 533 ? -37.494 61.023 -42.860 1.00 72.96 ? 534 ALA A C 1 ATOM 4254 O O . ALA A 1 533 ? -37.529 62.246 -43.083 1.00 78.81 ? 534 ALA A O 1 ATOM 4255 C CB . ALA A 1 533 ? -35.440 60.271 -41.584 1.00 55.95 ? 534 ALA A CB 1 ATOM 4256 N N . THR A 1 534 ? -37.991 60.095 -43.693 1.00 81.52 ? 535 THR A N 1 ATOM 4257 C CA . THR A 1 534 ? -38.481 60.391 -45.058 1.00 81.05 ? 535 THR A CA 1 ATOM 4258 C C . THR A 1 534 ? -40.017 60.401 -45.178 1.00 91.91 ? 535 THR A C 1 ATOM 4259 O O . THR A 1 534 ? -40.697 61.386 -44.831 1.00 104.15 ? 535 THR A O 1 ATOM 4260 C CB . THR A 1 534 ? -37.868 59.413 -46.113 1.00 80.92 ? 535 THR A CB 1 ATOM 4261 O OG1 . THR A 1 534 ? -37.627 58.115 -45.553 1.00 62.19 ? 535 THR A OG1 1 ATOM 4262 C CG2 . THR A 1 534 ? -36.549 59.917 -46.593 1.00 79.09 ? 535 THR A CG2 1 ATOM 4263 O OXT . THR A 1 534 ? -40.631 59.441 -45.647 1.00 90.14 ? 535 THR A OXT 1 HETATM 4264 C C1 . NAG B 2 . ? -74.449 12.835 -26.679 1.00 67.39 ? 601 NAG A C1 1 HETATM 4265 C C2 . NAG B 2 . ? -74.804 11.369 -26.458 1.00 77.42 ? 601 NAG A C2 1 HETATM 4266 C C3 . NAG B 2 . ? -74.105 10.479 -27.479 1.00 77.88 ? 601 NAG A C3 1 HETATM 4267 C C4 . NAG B 2 . ? -74.303 11.010 -28.893 1.00 82.97 ? 601 NAG A C4 1 HETATM 4268 C C5 . NAG B 2 . ? -73.979 12.497 -28.968 1.00 76.77 ? 601 NAG A C5 1 HETATM 4269 C C6 . NAG B 2 . ? -74.250 13.046 -30.364 1.00 74.97 ? 601 NAG A C6 1 HETATM 4270 C C7 . NAG B 2 . ? -75.333 10.912 -24.135 1.00 73.05 ? 601 NAG A C7 1 HETATM 4271 C C8 . NAG B 2 . ? -75.238 9.718 -23.232 1.00 74.36 ? 601 NAG A C8 1 HETATM 4272 N N2 . NAG B 2 . ? -74.435 10.967 -25.115 1.00 76.00 ? 601 NAG A N2 1 HETATM 4273 O O3 . NAG B 2 . ? -74.630 9.149 -27.391 1.00 83.15 ? 601 NAG A O3 1 HETATM 4274 O O4 . NAG B 2 . ? -73.457 10.291 -29.797 1.00 91.25 ? 601 NAG A O4 1 HETATM 4275 O O5 . NAG B 2 . ? -74.771 13.205 -28.018 1.00 88.04 ? 601 NAG A O5 1 HETATM 4276 O O6 . NAG B 2 . ? -73.269 14.039 -30.686 1.00 66.36 ? 601 NAG A O6 1 HETATM 4277 O O7 . NAG B 2 . ? -76.179 11.778 -23.980 1.00 65.14 ? 601 NAG A O7 1 HETATM 4278 C C1 . NAG C 2 . ? -37.008 34.761 -10.654 1.00 45.05 ? 602 NAG A C1 1 HETATM 4279 C C2 . NAG C 2 . ? -35.514 34.933 -10.703 1.00 49.60 ? 602 NAG A C2 1 HETATM 4280 C C3 . NAG C 2 . ? -34.798 34.375 -9.501 1.00 59.50 ? 602 NAG A C3 1 HETATM 4281 C C4 . NAG C 2 . ? -35.425 34.931 -8.204 1.00 63.80 ? 602 NAG A C4 1 HETATM 4282 C C5 . NAG C 2 . ? -36.964 35.014 -8.196 1.00 59.13 ? 602 NAG A C5 1 HETATM 4283 C C6 . NAG C 2 . ? -37.355 36.092 -7.152 1.00 51.72 ? 602 NAG A C6 1 HETATM 4284 C C7 . NAG C 2 . ? -34.588 34.940 -12.910 1.00 39.44 ? 602 NAG A C7 1 HETATM 4285 C C8 . NAG C 2 . ? -34.132 34.152 -14.086 1.00 41.86 ? 602 NAG A C8 1 HETATM 4286 N N2 . NAG C 2 . ? -35.007 34.258 -11.863 1.00 46.99 ? 602 NAG A N2 1 HETATM 4287 O O3 . NAG C 2 . ? -33.482 34.861 -9.694 1.00 52.22 ? 602 NAG A O3 1 HETATM 4288 O O4 . NAG C 2 . ? -34.924 34.263 -7.048 1.00 75.62 ? 602 NAG A O4 1 HETATM 4289 O O5 . NAG C 2 . ? -37.504 35.375 -9.483 1.00 51.17 ? 602 NAG A O5 1 HETATM 4290 O O6 . NAG C 2 . ? -38.734 36.278 -6.901 1.00 49.70 ? 602 NAG A O6 1 HETATM 4291 O O7 . NAG C 2 . ? -34.596 36.171 -12.949 1.00 43.31 ? 602 NAG A O7 1 HETATM 4292 C C1 . NAG D 2 . ? -34.333 35.239 -6.171 1.00 83.66 ? 603 NAG A C1 1 HETATM 4293 C C2 . NAG D 2 . ? -34.293 34.686 -4.751 1.00 90.05 ? 603 NAG A C2 1 HETATM 4294 C C3 . NAG D 2 . ? -33.658 35.687 -3.793 1.00 96.21 ? 603 NAG A C3 1 HETATM 4295 C C4 . NAG D 2 . ? -32.338 36.211 -4.346 1.00 96.60 ? 603 NAG A C4 1 HETATM 4296 C C5 . NAG D 2 . ? -32.496 36.673 -5.789 1.00 100.24 ? 603 NAG A C5 1 HETATM 4297 C C6 . NAG D 2 . ? -31.161 37.127 -6.367 1.00 88.87 ? 603 NAG A C6 1 HETATM 4298 C C7 . NAG D 2 . ? -36.089 33.109 -4.336 1.00 74.10 ? 603 NAG A C7 1 HETATM 4299 C C8 . NAG D 2 . ? -37.481 32.913 -3.812 1.00 66.29 ? 603 NAG A C8 1 HETATM 4300 N N2 . NAG D 2 . ? -35.634 34.358 -4.308 1.00 82.54 ? 603 NAG A N2 1 HETATM 4301 O O3 . NAG D 2 . ? -33.429 35.056 -2.527 1.00 91.59 ? 603 NAG A O3 1 HETATM 4302 O O4 . NAG D 2 . ? -31.884 37.305 -3.541 1.00 85.25 ? 603 NAG A O4 1 HETATM 4303 O O5 . NAG D 2 . ? -33.016 35.604 -6.576 1.00 93.82 ? 603 NAG A O5 1 HETATM 4304 O O6 . NAG D 2 . ? -30.430 35.986 -6.832 1.00 81.69 ? 603 NAG A O6 1 HETATM 4305 O O7 . NAG D 2 . ? -35.418 32.182 -4.759 1.00 62.31 ? 603 NAG A O7 1 HETATM 4306 C CA . OMI E 3 . ? -50.879 27.725 -39.150 1.00 79.18 ? 604 OMI A CA 1 HETATM 4307 C C . OMI E 3 . ? -51.948 28.531 -39.191 1.00 77.80 ? 604 OMI A C 1 HETATM 4308 O O . OMI E 3 . ? -52.470 28.976 -38.187 1.00 58.08 ? 604 OMI A O 1 HETATM 4309 C CAI . OMI E 3 . ? -52.384 28.670 -40.440 1.00 85.64 ? 604 OMI A CAI 1 HETATM 4310 C CAE . OMI E 3 . ? -53.400 29.331 -40.964 1.00 85.54 ? 604 OMI A CAE 1 HETATM 4311 C CAC . OMI E 3 . ? -53.635 29.302 -42.324 1.00 90.55 ? 604 OMI A CAC 1 HETATM 4312 C CAD . OMI E 3 . ? -52.812 28.567 -43.151 1.00 89.98 ? 604 OMI A CAD 1 HETATM 4313 C CAF . OMI E 3 . ? -51.772 27.913 -42.538 1.00 89.32 ? 604 OMI A CAF 1 HETATM 4314 C CAJ . OMI E 3 . ? -51.584 27.973 -41.221 1.00 86.45 ? 604 OMI A CAJ 1 HETATM 4315 N N . OMI E 3 . ? -50.630 27.432 -40.551 1.00 80.55 ? 604 OMI A N 1 HETATM 4316 C CAA . OMI E 3 . ? -49.467 28.233 -40.893 1.00 87.71 ? 604 OMI A CAA 1 HETATM 4317 C C1 . PG4 F 4 . ? -52.115 30.227 -45.953 1.00 58.65 ? 605 PG4 A C1 1 HETATM 4318 C C2 . PG4 F 4 . ? -51.776 31.718 -45.926 1.00 61.19 ? 605 PG4 A C2 1 HETATM 4319 O O2 . PG4 F 4 . ? -52.888 32.528 -46.462 1.00 66.29 ? 605 PG4 A O2 1 HETATM 4320 C C3 . PG4 F 4 . ? -52.505 33.903 -46.292 1.00 67.95 ? 605 PG4 A C3 1 HETATM 4321 C C4 . PG4 F 4 . ? -53.609 34.845 -46.677 1.00 64.77 ? 605 PG4 A C4 1 HETATM 4322 O O3 . PG4 F 4 . ? -54.659 34.101 -47.327 1.00 76.17 ? 605 PG4 A O3 1 HETATM 4323 C C5 . PG4 F 4 . ? -55.089 34.815 -48.516 1.00 73.75 ? 605 PG4 A C5 1 HETATM 4324 C C6 . PG4 F 4 . ? -56.544 34.533 -48.827 1.00 69.11 ? 605 PG4 A C6 1 HETATM 4325 O O4 . PG4 F 4 . ? -57.166 35.771 -49.154 1.00 67.64 ? 605 PG4 A O4 1 HETATM 4326 C C7 . PG4 F 4 . ? -56.701 36.282 -50.421 1.00 70.36 ? 605 PG4 A C7 1 HETATM 4327 C C8 . PG4 F 4 . ? -57.474 37.544 -50.745 1.00 73.94 ? 605 PG4 A C8 1 HETATM 4328 O O5 . PG4 F 4 . ? -58.552 37.135 -51.621 1.00 64.10 ? 605 PG4 A O5 1 HETATM 4329 C C . ACT G 5 . ? -51.375 32.791 -38.614 1.00 51.70 ? 606 ACT A C 1 HETATM 4330 O O . ACT G 5 . ? -51.357 31.573 -38.934 1.00 59.60 ? 606 ACT A O 1 HETATM 4331 O OXT . ACT G 5 . ? -51.863 33.282 -37.568 1.00 37.19 ? 606 ACT A OXT 1 HETATM 4332 C CH3 . ACT G 5 . ? -50.801 33.765 -39.634 1.00 52.83 ? 606 ACT A CH3 1 HETATM 4333 O O . HOH H 6 . ? -53.891 9.960 -13.758 1.00 43.54 ? 701 HOH A O 1 HETATM 4334 O O . HOH H 6 . ? -59.783 11.217 -16.229 1.00 34.24 ? 702 HOH A O 1 HETATM 4335 O O . HOH H 6 . ? -34.812 12.792 -33.065 1.00 38.36 ? 703 HOH A O 1 HETATM 4336 O O . HOH H 6 . ? -32.408 19.799 -31.116 1.00 53.89 ? 704 HOH A O 1 HETATM 4337 O O . HOH H 6 . ? -76.333 45.012 -28.402 1.00 59.10 ? 705 HOH A O 1 HETATM 4338 O O . HOH H 6 . ? -32.246 18.438 -23.560 1.00 44.51 ? 706 HOH A O 1 HETATM 4339 O O . HOH H 6 . ? -48.947 4.206 -24.894 1.00 52.10 ? 707 HOH A O 1 HETATM 4340 O O . HOH H 6 . ? -58.804 19.296 -8.184 1.00 49.06 ? 708 HOH A O 1 HETATM 4341 O O . HOH H 6 . ? -36.311 16.132 -42.657 1.00 55.86 ? 709 HOH A O 1 HETATM 4342 O O . HOH H 6 . ? -34.962 38.855 -14.491 1.00 22.96 ? 710 HOH A O 1 HETATM 4343 O O . HOH H 6 . ? -55.877 27.379 -36.344 1.00 23.85 ? 711 HOH A O 1 HETATM 4344 O O . HOH H 6 . ? -43.883 29.556 -60.027 1.00 30.38 ? 712 HOH A O 1 HETATM 4345 O O . HOH H 6 . ? -38.172 46.214 -21.824 1.00 27.40 ? 713 HOH A O 1 HETATM 4346 O O . HOH H 6 . ? -37.735 21.750 -14.509 1.00 37.08 ? 714 HOH A O 1 HETATM 4347 O O . HOH H 6 . ? -76.197 21.256 -14.165 1.00 37.84 ? 715 HOH A O 1 HETATM 4348 O O . HOH H 6 . ? -59.932 39.512 -40.883 1.00 29.61 ? 716 HOH A O 1 HETATM 4349 O O . HOH H 6 . ? -63.900 25.323 -29.509 1.00 30.88 ? 717 HOH A O 1 HETATM 4350 O O . HOH H 6 . ? -60.141 16.509 -35.226 1.00 44.90 ? 718 HOH A O 1 HETATM 4351 O O . HOH H 6 . ? -61.837 51.772 -34.235 1.00 27.56 ? 719 HOH A O 1 HETATM 4352 O O . HOH H 6 . ? -71.709 36.297 -25.441 1.00 29.91 ? 720 HOH A O 1 HETATM 4353 O O . HOH H 6 . ? -30.767 30.455 -51.379 1.00 40.62 ? 721 HOH A O 1 HETATM 4354 O O . HOH H 6 . ? -77.158 30.238 -22.373 1.00 50.62 ? 722 HOH A O 1 HETATM 4355 O O . HOH H 6 . ? -44.552 10.074 -20.847 1.00 56.44 ? 723 HOH A O 1 HETATM 4356 O O . HOH H 6 . ? -62.770 35.283 -41.829 1.00 24.60 ? 724 HOH A O 1 HETATM 4357 O O . HOH H 6 . ? -50.708 39.629 -12.524 1.00 46.46 ? 725 HOH A O 1 HETATM 4358 O O . HOH H 6 . ? -34.983 25.854 -44.994 1.00 41.60 ? 726 HOH A O 1 HETATM 4359 O O . HOH H 6 . ? -71.361 30.215 -28.507 1.00 29.46 ? 727 HOH A O 1 HETATM 4360 O O . HOH H 6 . ? -57.156 24.627 -50.132 1.00 37.36 ? 728 HOH A O 1 HETATM 4361 O O . HOH H 6 . ? -34.693 14.353 -30.583 1.00 41.42 ? 729 HOH A O 1 HETATM 4362 O O . HOH H 6 . ? -45.324 28.397 -36.509 1.00 23.08 ? 730 HOH A O 1 HETATM 4363 O O . HOH H 6 . ? -59.805 27.981 -55.688 1.00 40.45 ? 731 HOH A O 1 HETATM 4364 O O . HOH H 6 . ? -36.555 31.522 -13.893 1.00 47.50 ? 732 HOH A O 1 HETATM 4365 O O . HOH H 6 . ? -44.239 41.076 -61.032 1.00 40.66 ? 733 HOH A O 1 HETATM 4366 O O . HOH H 6 . ? -70.556 31.155 -43.902 1.00 48.31 ? 734 HOH A O 1 HETATM 4367 O O . HOH H 6 . ? -41.210 31.967 -60.893 1.00 31.78 ? 735 HOH A O 1 HETATM 4368 O O . HOH H 6 . ? -34.082 37.748 -63.642 1.00 38.19 ? 736 HOH A O 1 HETATM 4369 O O . HOH H 6 . ? -48.375 33.066 -56.032 1.00 8.46 ? 737 HOH A O 1 HETATM 4370 O O . HOH H 6 . ? -48.813 44.502 -33.204 1.00 24.25 ? 738 HOH A O 1 HETATM 4371 O O . HOH H 6 . ? -34.857 31.837 -40.782 1.00 40.98 ? 739 HOH A O 1 HETATM 4372 O O . HOH H 6 . ? -57.784 21.326 -29.300 1.00 35.39 ? 740 HOH A O 1 HETATM 4373 O O . HOH H 6 . ? -48.538 26.271 -15.995 1.00 37.20 ? 741 HOH A O 1 HETATM 4374 O O . HOH H 6 . ? -48.150 21.051 -37.785 1.00 33.62 ? 742 HOH A O 1 HETATM 4375 O O . HOH H 6 . ? -51.616 16.276 -28.115 1.00 25.62 ? 743 HOH A O 1 HETATM 4376 O O . HOH H 6 . ? -65.481 26.463 -31.235 1.00 31.15 ? 744 HOH A O 1 HETATM 4377 O O . HOH H 6 . ? -70.848 36.702 -33.927 1.00 30.75 ? 745 HOH A O 1 HETATM 4378 O O . HOH H 6 . ? -77.681 28.320 -19.772 1.00 53.04 ? 746 HOH A O 1 HETATM 4379 O O . HOH H 6 . ? -68.456 32.003 -18.416 1.00 45.08 ? 747 HOH A O 1 HETATM 4380 O O . HOH H 6 . ? -45.456 41.338 -45.364 1.00 25.23 ? 748 HOH A O 1 HETATM 4381 O O . HOH H 6 . ? -61.926 12.784 -15.614 1.00 41.33 ? 749 HOH A O 1 HETATM 4382 O O . HOH H 6 . ? -60.348 40.370 -16.127 1.00 37.29 ? 750 HOH A O 1 HETATM 4383 O O . HOH H 6 . ? -59.465 30.117 -51.043 1.00 39.11 ? 751 HOH A O 1 HETATM 4384 O O . HOH H 6 . ? -24.070 31.709 -32.095 1.00 49.28 ? 752 HOH A O 1 HETATM 4385 O O . HOH H 6 . ? -24.360 38.342 -27.223 1.00 51.47 ? 753 HOH A O 1 HETATM 4386 O O . HOH H 6 . ? -76.025 37.012 -35.888 1.00 29.11 ? 754 HOH A O 1 HETATM 4387 O O . HOH H 6 . ? -44.543 26.512 -10.799 1.00 35.43 ? 755 HOH A O 1 HETATM 4388 O O . HOH H 6 . ? -36.444 48.482 -21.981 1.00 49.01 ? 756 HOH A O 1 HETATM 4389 O O . HOH H 6 . ? -30.932 34.797 -50.822 1.00 36.57 ? 757 HOH A O 1 HETATM 4390 O O . HOH H 6 . ? -69.340 38.731 -33.165 1.00 29.64 ? 758 HOH A O 1 HETATM 4391 O O . HOH H 6 . ? -45.839 16.935 -42.011 1.00 35.88 ? 759 HOH A O 1 HETATM 4392 O O . HOH H 6 . ? -27.991 31.322 -19.808 1.00 34.46 ? 760 HOH A O 1 HETATM 4393 O O . HOH H 6 . ? -55.464 26.552 -45.127 1.00 33.61 ? 761 HOH A O 1 HETATM 4394 O O . HOH H 6 . ? -65.864 31.575 -14.830 1.00 33.62 ? 762 HOH A O 1 HETATM 4395 O O . HOH H 6 . ? -77.178 34.883 -27.010 1.00 46.48 ? 763 HOH A O 1 HETATM 4396 O O . HOH H 6 . ? -72.460 52.231 -31.279 1.00 52.17 ? 764 HOH A O 1 HETATM 4397 O O . HOH H 6 . ? -30.969 38.251 -29.377 1.00 36.66 ? 765 HOH A O 1 HETATM 4398 O O . HOH H 6 . ? -44.096 29.623 -44.152 1.00 35.81 ? 766 HOH A O 1 HETATM 4399 O O . HOH H 6 . ? -69.820 45.270 -26.177 1.00 42.15 ? 767 HOH A O 1 HETATM 4400 O O . HOH H 6 . ? -53.764 32.682 -53.670 1.00 48.09 ? 768 HOH A O 1 HETATM 4401 O O . HOH H 6 . ? -48.361 18.757 -12.896 1.00 53.19 ? 769 HOH A O 1 HETATM 4402 O O . HOH H 6 . ? -65.341 51.511 -27.686 1.00 41.10 ? 770 HOH A O 1 HETATM 4403 O O . HOH H 6 . ? -62.644 34.285 -9.863 1.00 54.44 ? 771 HOH A O 1 HETATM 4404 O O . HOH H 6 . ? -36.435 29.348 -15.478 1.00 36.40 ? 772 HOH A O 1 HETATM 4405 O O . HOH H 6 . ? -38.866 33.009 -43.833 1.00 32.61 ? 773 HOH A O 1 HETATM 4406 O O . HOH H 6 . ? -33.560 17.917 -38.459 1.00 39.78 ? 774 HOH A O 1 HETATM 4407 O O . HOH H 6 . ? -59.312 20.591 -41.184 1.00 33.95 ? 775 HOH A O 1 HETATM 4408 O O . HOH H 6 . ? -60.122 26.717 -39.010 1.00 25.14 ? 776 HOH A O 1 HETATM 4409 O O . HOH H 6 . ? -42.151 10.697 -24.108 1.00 31.80 ? 777 HOH A O 1 HETATM 4410 O O . HOH H 6 . ? -63.104 45.999 -26.287 1.00 42.87 ? 778 HOH A O 1 HETATM 4411 O O . HOH H 6 . ? -36.412 12.355 -39.492 1.00 35.29 ? 779 HOH A O 1 HETATM 4412 O O . HOH H 6 . ? -52.185 27.860 -34.702 1.00 24.64 ? 780 HOH A O 1 HETATM 4413 O O . HOH H 6 . ? -56.788 30.464 -16.577 1.00 35.34 ? 781 HOH A O 1 HETATM 4414 O O . HOH H 6 . ? -69.433 34.247 -33.553 1.00 31.78 ? 782 HOH A O 1 HETATM 4415 O O . HOH H 6 . ? -63.095 28.735 -34.459 1.00 26.44 ? 783 HOH A O 1 HETATM 4416 O O . HOH H 6 . ? -28.335 33.692 -22.690 1.00 38.72 ? 784 HOH A O 1 HETATM 4417 O O . HOH H 6 . ? -59.890 45.736 -36.281 1.00 24.42 ? 785 HOH A O 1 HETATM 4418 O O . HOH H 6 . ? -42.443 28.061 -33.929 1.00 29.14 ? 786 HOH A O 1 HETATM 4419 O O . HOH H 6 . ? -66.123 44.690 -31.493 1.00 28.39 ? 787 HOH A O 1 HETATM 4420 O O . HOH H 6 . ? -54.787 53.355 -31.746 1.00 26.92 ? 788 HOH A O 1 HETATM 4421 O O . HOH H 6 . ? -49.733 48.628 -32.752 1.00 24.76 ? 789 HOH A O 1 HETATM 4422 O O . HOH H 6 . ? -51.335 46.335 -38.857 1.00 28.06 ? 790 HOH A O 1 HETATM 4423 O O . HOH H 6 . ? -50.302 35.649 -48.800 1.00 36.16 ? 791 HOH A O 1 HETATM 4424 O O . HOH H 6 . ? -47.335 47.273 -51.540 1.00 48.59 ? 792 HOH A O 1 HETATM 4425 O O . HOH H 6 . ? -57.909 39.141 -39.261 1.00 23.63 ? 793 HOH A O 1 HETATM 4426 O O . HOH H 6 . ? -62.545 47.311 -37.919 1.00 23.42 ? 794 HOH A O 1 HETATM 4427 O O . HOH H 6 . ? -56.430 55.025 -41.060 1.00 37.56 ? 795 HOH A O 1 HETATM 4428 O O . HOH H 6 . ? -60.349 44.782 -33.019 1.00 26.52 ? 796 HOH A O 1 HETATM 4429 O O . HOH H 6 . ? -37.712 29.632 -50.086 1.00 34.51 ? 797 HOH A O 1 HETATM 4430 O O . HOH H 6 . ? -43.061 47.170 -30.472 1.00 48.22 ? 798 HOH A O 1 HETATM 4431 O O . HOH H 6 . ? -51.821 41.201 -54.926 1.00 33.21 ? 799 HOH A O 1 HETATM 4432 O O . HOH H 6 . ? -56.673 33.497 -35.822 1.00 20.62 ? 800 HOH A O 1 HETATM 4433 O O . HOH H 6 . ? -56.200 27.107 -39.183 1.00 24.09 ? 801 HOH A O 1 HETATM 4434 O O . HOH H 6 . ? -55.548 19.359 -38.748 1.00 32.07 ? 802 HOH A O 1 HETATM 4435 O O . HOH H 6 . ? -40.314 34.715 -61.428 1.00 33.96 ? 803 HOH A O 1 HETATM 4436 O O . HOH H 6 . ? -26.619 36.560 -61.400 1.00 50.29 ? 804 HOH A O 1 HETATM 4437 O O . HOH H 6 . ? -36.954 21.935 -47.826 1.00 48.50 ? 805 HOH A O 1 HETATM 4438 O O . HOH H 6 . ? -62.557 31.156 -8.777 1.00 53.62 ? 806 HOH A O 1 HETATM 4439 O O . HOH H 6 . ? -52.901 42.857 -40.366 1.00 28.52 ? 807 HOH A O 1 HETATM 4440 O O . HOH H 6 . ? -51.352 50.273 -17.264 1.00 34.58 ? 808 HOH A O 1 HETATM 4441 O O . HOH H 6 . ? -52.114 29.836 -13.364 1.00 27.07 ? 809 HOH A O 1 HETATM 4442 O O . HOH H 6 . ? -42.479 12.531 -20.495 1.00 58.14 ? 810 HOH A O 1 HETATM 4443 O O . HOH H 6 . ? -66.507 30.838 -45.430 1.00 33.41 ? 811 HOH A O 1 HETATM 4444 O O . HOH H 6 . ? -51.151 37.169 -46.769 1.00 33.18 ? 812 HOH A O 1 HETATM 4445 O O . HOH H 6 . ? -34.845 19.398 -41.852 1.00 42.70 ? 813 HOH A O 1 HETATM 4446 O O . HOH H 6 . ? -56.707 31.331 -49.501 1.00 47.22 ? 814 HOH A O 1 HETATM 4447 O O . HOH H 6 . ? -57.394 27.084 -29.413 1.00 21.43 ? 815 HOH A O 1 HETATM 4448 O O . HOH H 6 . ? -56.090 29.244 -41.040 1.00 29.81 ? 816 HOH A O 1 HETATM 4449 O O . HOH H 6 . ? -47.561 20.059 -52.840 1.00 36.48 ? 817 HOH A O 1 HETATM 4450 O O . HOH H 6 . ? -35.083 24.451 -55.867 1.00 42.96 ? 818 HOH A O 1 HETATM 4451 O O . HOH H 6 . ? -55.929 30.433 -13.585 1.00 33.37 ? 819 HOH A O 1 HETATM 4452 O O . HOH H 6 . ? -36.192 34.186 -42.138 1.00 37.46 ? 820 HOH A O 1 HETATM 4453 O O . HOH H 6 . ? -50.921 43.195 -57.451 1.00 36.48 ? 821 HOH A O 1 HETATM 4454 O O . HOH H 6 . ? -42.891 13.338 -24.488 1.00 33.53 ? 822 HOH A O 1 HETATM 4455 O O . HOH H 6 . ? -32.198 27.374 -16.850 1.00 37.56 ? 823 HOH A O 1 HETATM 4456 O O . HOH H 6 . ? -76.157 39.532 -35.997 1.00 32.90 ? 824 HOH A O 1 HETATM 4457 O O . HOH H 6 . ? -65.719 34.490 -36.368 1.00 27.30 ? 825 HOH A O 1 HETATM 4458 O O . HOH H 6 . ? -37.634 36.947 -18.718 1.00 26.56 ? 826 HOH A O 1 HETATM 4459 O O . HOH H 6 . ? -33.992 35.128 -18.705 1.00 33.73 ? 827 HOH A O 1 HETATM 4460 O O . HOH H 6 . ? -71.226 29.201 -25.987 1.00 29.19 ? 828 HOH A O 1 HETATM 4461 O O . HOH H 6 . ? -56.304 30.834 -45.122 1.00 57.56 ? 829 HOH A O 1 HETATM 4462 O O . HOH H 6 . ? -36.874 11.826 -27.207 1.00 33.67 ? 830 HOH A O 1 HETATM 4463 O O . HOH H 6 . ? -39.172 39.350 -12.986 1.00 37.10 ? 831 HOH A O 1 HETATM 4464 O O . HOH H 6 . ? -21.743 35.387 -54.514 1.00 47.78 ? 832 HOH A O 1 HETATM 4465 O O . HOH H 6 . ? -32.356 26.611 -50.865 1.00 40.84 ? 833 HOH A O 1 HETATM 4466 O O . HOH H 6 . ? -45.676 20.337 -54.823 1.00 36.23 ? 834 HOH A O 1 HETATM 4467 O O . HOH H 6 . ? -54.458 6.220 -19.267 1.00 48.66 ? 835 HOH A O 1 HETATM 4468 O O . HOH H 6 . ? -65.137 38.310 -41.189 1.00 24.85 ? 836 HOH A O 1 HETATM 4469 O O . HOH H 6 . ? -60.385 26.038 -10.715 1.00 26.36 ? 837 HOH A O 1 HETATM 4470 O O . HOH H 6 . ? -32.726 30.159 -24.752 1.00 31.34 ? 838 HOH A O 1 HETATM 4471 O O . HOH H 6 . ? -52.222 40.946 -46.971 1.00 41.80 ? 839 HOH A O 1 HETATM 4472 O O . HOH H 6 . ? -53.337 42.602 -13.373 1.00 27.61 ? 840 HOH A O 1 HETATM 4473 O O . HOH H 6 . ? -45.270 8.480 -36.997 1.00 47.98 ? 841 HOH A O 1 HETATM 4474 O O . HOH H 6 . ? -51.412 39.228 -52.935 1.00 33.58 ? 842 HOH A O 1 HETATM 4475 O O . HOH H 6 . ? -30.805 35.349 -29.602 1.00 28.34 ? 843 HOH A O 1 HETATM 4476 O O . HOH H 6 . ? -21.090 31.853 -22.374 1.00 53.69 ? 844 HOH A O 1 HETATM 4477 O O . HOH H 6 . ? -55.844 40.103 -14.934 1.00 32.09 ? 845 HOH A O 1 HETATM 4478 O O . HOH H 6 . ? -54.462 53.266 -43.960 1.00 46.48 ? 846 HOH A O 1 HETATM 4479 O O . HOH H 6 . ? -44.832 54.480 -28.537 1.00 41.35 ? 847 HOH A O 1 HETATM 4480 O O . HOH H 6 . ? -43.028 37.888 -55.913 1.00 38.04 ? 848 HOH A O 1 HETATM 4481 O O . HOH H 6 . ? -44.506 32.274 -12.362 1.00 41.59 ? 849 HOH A O 1 HETATM 4482 O O . HOH H 6 . ? -36.932 38.192 -12.126 1.00 37.39 ? 850 HOH A O 1 HETATM 4483 O O . HOH H 6 . ? -52.805 45.553 -41.036 1.00 23.08 ? 851 HOH A O 1 HETATM 4484 O O . HOH H 6 . ? -59.957 28.735 -42.598 1.00 43.71 ? 852 HOH A O 1 HETATM 4485 O O . HOH H 6 . ? -45.932 44.276 -56.126 1.00 40.12 ? 853 HOH A O 1 HETATM 4486 O O . HOH H 6 . ? -59.509 45.045 -20.838 1.00 38.03 ? 854 HOH A O 1 HETATM 4487 O O . HOH H 6 . ? -71.529 40.067 -49.427 1.00 42.98 ? 855 HOH A O 1 HETATM 4488 O O . HOH H 6 . ? -68.165 33.457 -35.774 1.00 30.83 ? 856 HOH A O 1 HETATM 4489 O O . HOH H 6 . ? -59.682 50.499 -48.962 1.00 43.93 ? 857 HOH A O 1 HETATM 4490 O O . HOH H 6 . ? -29.672 20.583 -32.864 1.00 48.44 ? 858 HOH A O 1 HETATM 4491 O O . HOH H 6 . ? -67.794 24.160 -42.157 1.00 42.58 ? 859 HOH A O 1 HETATM 4492 O O . HOH H 6 . ? -31.449 48.690 -53.683 1.00 39.26 ? 860 HOH A O 1 HETATM 4493 O O . HOH H 6 . ? -50.321 30.054 -55.627 1.00 42.68 ? 861 HOH A O 1 HETATM 4494 O O . HOH H 6 . ? -37.480 17.258 -23.167 1.00 36.46 ? 862 HOH A O 1 HETATM 4495 O O . HOH H 6 . ? -56.008 56.095 -34.083 1.00 33.84 ? 863 HOH A O 1 HETATM 4496 O O . HOH H 6 . ? -70.278 25.150 -42.186 1.00 39.56 ? 864 HOH A O 1 HETATM 4497 O O . HOH H 6 . ? -46.556 8.449 -24.872 1.00 49.39 ? 865 HOH A O 1 HETATM 4498 O O . HOH H 6 . ? -46.323 40.755 -13.040 1.00 26.64 ? 866 HOH A O 1 HETATM 4499 O O . HOH H 6 . ? -30.805 38.755 -32.102 1.00 37.18 ? 867 HOH A O 1 HETATM 4500 O O . HOH H 6 . ? -46.652 5.970 -26.343 1.00 47.82 ? 868 HOH A O 1 HETATM 4501 O O . HOH H 6 . ? -63.853 38.763 -21.275 1.00 36.35 ? 869 HOH A O 1 HETATM 4502 O O . HOH H 6 . ? -59.991 13.500 -28.584 1.00 34.66 ? 870 HOH A O 1 HETATM 4503 O O . HOH H 6 . ? -63.317 54.286 -44.441 1.00 43.63 ? 871 HOH A O 1 HETATM 4504 O O . HOH H 6 . ? -40.158 44.315 -38.743 1.00 35.16 ? 872 HOH A O 1 HETATM 4505 O O . HOH H 6 . ? -38.132 57.335 -51.177 1.00 45.51 ? 873 HOH A O 1 HETATM 4506 O O . HOH H 6 . ? -64.869 35.674 -40.129 1.00 25.46 ? 874 HOH A O 1 HETATM 4507 O O . HOH H 6 . ? -60.778 38.622 -13.238 1.00 41.63 ? 875 HOH A O 1 HETATM 4508 O O . HOH H 6 . ? -53.598 1.722 -20.186 1.00 53.81 ? 876 HOH A O 1 HETATM 4509 O O . HOH H 6 . ? -66.473 15.344 -32.296 1.00 36.97 ? 877 HOH A O 1 HETATM 4510 O O . HOH H 6 . ? -39.573 47.208 -39.684 1.00 42.98 ? 878 HOH A O 1 HETATM 4511 O O . HOH H 6 . ? -29.542 28.199 -18.097 1.00 43.13 ? 879 HOH A O 1 HETATM 4512 O O . HOH H 6 . ? -78.255 36.779 -28.643 1.00 38.79 ? 880 HOH A O 1 HETATM 4513 O O . HOH H 6 . ? -60.866 56.566 -39.492 1.00 35.77 ? 881 HOH A O 1 HETATM 4514 O O . HOH H 6 . ? -78.115 50.248 -43.834 1.00 42.10 ? 882 HOH A O 1 HETATM 4515 O O . HOH H 6 . ? -40.953 19.339 -53.595 1.00 33.07 ? 883 HOH A O 1 HETATM 4516 O O . HOH H 6 . ? -46.356 50.275 -30.353 1.00 22.85 ? 884 HOH A O 1 HETATM 4517 O O . HOH H 6 . ? -37.568 42.505 -12.847 1.00 33.34 ? 885 HOH A O 1 HETATM 4518 O O . HOH H 6 . ? -47.518 16.811 -14.495 1.00 49.92 ? 886 HOH A O 1 HETATM 4519 O O . HOH H 6 . ? -27.930 28.831 -55.434 1.00 41.83 ? 887 HOH A O 1 HETATM 4520 O O . HOH H 6 . ? -46.005 22.525 -10.419 1.00 46.66 ? 888 HOH A O 1 HETATM 4521 O O . HOH H 6 . ? -58.139 18.895 -39.179 1.00 32.07 ? 889 HOH A O 1 HETATM 4522 O O . HOH H 6 . ? -37.072 18.017 -20.592 1.00 50.71 ? 890 HOH A O 1 HETATM 4523 O O . HOH H 6 . ? -48.535 30.852 -59.310 1.00 40.82 ? 891 HOH A O 1 HETATM 4524 O O . HOH H 6 . ? -57.034 21.885 -8.175 1.00 49.24 ? 892 HOH A O 1 HETATM 4525 O O . HOH H 6 . ? -62.198 38.319 -16.788 1.00 34.65 ? 893 HOH A O 1 HETATM 4526 O O . HOH H 6 . ? -47.445 46.669 -14.089 1.00 35.58 ? 894 HOH A O 1 HETATM 4527 O O . HOH H 6 . ? -52.686 46.244 -46.337 1.00 24.93 ? 895 HOH A O 1 HETATM 4528 O O . HOH H 6 . ? -52.234 15.820 -9.222 1.00 48.17 ? 896 HOH A O 1 HETATM 4529 O O . HOH H 6 . ? -73.965 31.087 -38.044 1.00 33.93 ? 897 HOH A O 1 HETATM 4530 O O . HOH H 6 . ? -29.470 37.900 -39.698 1.00 29.16 ? 898 HOH A O 1 HETATM 4531 O O . HOH H 6 . ? -34.673 44.985 -30.844 1.00 31.42 ? 899 HOH A O 1 HETATM 4532 O O . HOH H 6 . ? -48.717 50.060 -30.621 1.00 25.77 ? 900 HOH A O 1 HETATM 4533 O O . HOH H 6 . ? -48.944 55.345 -26.043 1.00 44.69 ? 901 HOH A O 1 HETATM 4534 O O . HOH H 6 . ? -27.242 37.637 -38.305 1.00 33.05 ? 902 HOH A O 1 HETATM 4535 O O . HOH H 6 . ? -51.273 32.287 -12.177 1.00 26.31 ? 903 HOH A O 1 HETATM 4536 O O . HOH H 6 . ? -31.021 53.111 -54.475 1.00 50.21 ? 904 HOH A O 1 HETATM 4537 O O . HOH H 6 . ? -41.828 20.465 -40.069 1.00 44.17 ? 905 HOH A O 1 HETATM 4538 O O . HOH H 6 . ? -59.909 46.605 -38.635 1.00 32.68 ? 906 HOH A O 1 HETATM 4539 O O . HOH H 6 . ? -37.527 5.834 -39.012 1.00 42.94 ? 907 HOH A O 1 HETATM 4540 O O . HOH H 6 . ? -41.635 45.755 -33.024 1.00 31.27 ? 908 HOH A O 1 HETATM 4541 O O . HOH H 6 . ? -52.563 49.418 -42.130 1.00 29.08 ? 909 HOH A O 1 HETATM 4542 O O . HOH H 6 . ? -31.146 26.527 -40.224 1.00 38.89 ? 910 HOH A O 1 HETATM 4543 O O . HOH H 6 . ? -39.410 22.839 -54.539 1.00 25.18 ? 911 HOH A O 1 HETATM 4544 O O . HOH H 6 . ? -49.387 34.262 -11.872 1.00 30.77 ? 912 HOH A O 1 HETATM 4545 O O . HOH H 6 . ? -73.739 28.053 -25.548 1.00 36.48 ? 913 HOH A O 1 HETATM 4546 O O . HOH H 6 . ? -39.189 46.362 -33.647 1.00 38.83 ? 914 HOH A O 1 HETATM 4547 O O . HOH H 6 . ? -46.621 34.439 -12.593 1.00 44.46 ? 915 HOH A O 1 HETATM 4548 O O . HOH H 6 . ? -52.844 50.968 -38.126 1.00 25.26 ? 916 HOH A O 1 HETATM 4549 O O . HOH H 6 . ? -53.531 15.478 -50.301 1.00 42.11 ? 917 HOH A O 1 HETATM 4550 O O . HOH H 6 . ? -60.673 8.944 -11.906 1.00 45.97 ? 918 HOH A O 1 HETATM 4551 O O . HOH H 6 . ? -63.403 26.370 -33.177 1.00 32.87 ? 919 HOH A O 1 HETATM 4552 O O . HOH H 6 . ? -50.410 49.481 -51.997 1.00 36.78 ? 920 HOH A O 1 HETATM 4553 O O . HOH H 6 . ? -42.136 48.058 -14.440 1.00 49.73 ? 921 HOH A O 1 HETATM 4554 O O . HOH H 6 . ? -41.817 56.807 -52.286 1.00 39.35 ? 922 HOH A O 1 HETATM 4555 O O . HOH H 6 . ? -40.065 54.437 -58.780 1.00 62.36 ? 923 HOH A O 1 HETATM 4556 O O . HOH H 6 . ? -60.447 35.747 -10.934 1.00 40.66 ? 924 HOH A O 1 HETATM 4557 O O . HOH H 6 . ? -54.129 7.018 -30.968 1.00 33.93 ? 925 HOH A O 1 HETATM 4558 O O . HOH H 6 . ? -44.876 34.739 -62.585 1.00 49.30 ? 926 HOH A O 1 HETATM 4559 O O . HOH H 6 . ? -79.483 41.138 -35.516 1.00 63.25 ? 927 HOH A O 1 HETATM 4560 O O . HOH H 6 . ? -60.021 11.201 -30.559 1.00 41.39 ? 928 HOH A O 1 HETATM 4561 O O . HOH H 6 . ? -52.566 23.727 -3.342 1.00 34.87 ? 929 HOH A O 1 HETATM 4562 O O . HOH H 6 . ? -57.590 49.735 -51.050 1.00 45.44 ? 930 HOH A O 1 HETATM 4563 O O . HOH H 6 . ? -68.007 29.782 -13.910 1.00 36.57 ? 931 HOH A O 1 HETATM 4564 O O . HOH H 6 . ? -57.311 28.345 -43.502 1.00 41.20 ? 932 HOH A O 1 HETATM 4565 O O . HOH H 6 . ? -52.419 32.248 -42.206 1.00 65.70 ? 933 HOH A O 1 HETATM 4566 O O . HOH H 6 . ? -69.102 19.971 -6.568 1.00 46.01 ? 934 HOH A O 1 HETATM 4567 O O . HOH H 6 . ? -57.392 35.579 -11.209 1.00 46.43 ? 935 HOH A O 1 HETATM 4568 O O . HOH H 6 . ? -26.094 34.615 -51.246 1.00 45.80 ? 936 HOH A O 1 HETATM 4569 O O . HOH H 6 . ? -38.064 12.684 -24.988 1.00 40.56 ? 937 HOH A O 1 HETATM 4570 O O . HOH H 6 . ? -31.569 24.076 -15.997 1.00 41.61 ? 938 HOH A O 1 HETATM 4571 O O . HOH H 6 . ? -44.411 47.272 -43.887 1.00 31.59 ? 939 HOH A O 1 HETATM 4572 O O . HOH H 6 . ? -57.299 4.534 -15.911 1.00 47.26 ? 940 HOH A O 1 HETATM 4573 O O . HOH H 6 . ? -42.969 31.214 -10.625 1.00 43.51 ? 941 HOH A O 1 HETATM 4574 O O . HOH H 6 . ? -31.071 38.689 -18.196 1.00 41.76 ? 942 HOH A O 1 HETATM 4575 O O . HOH H 6 . ? -57.751 0.955 -20.387 1.00 47.39 ? 943 HOH A O 1 HETATM 4576 O O . HOH H 6 . ? -61.494 20.049 -42.918 1.00 57.12 ? 944 HOH A O 1 HETATM 4577 O O . HOH H 6 . ? -56.087 4.396 -18.137 1.00 52.50 ? 945 HOH A O 1 HETATM 4578 O O . HOH H 6 . ? -64.540 43.806 -21.254 1.00 47.12 ? 946 HOH A O 1 HETATM 4579 O O . HOH H 6 . ? -54.326 40.630 -49.288 1.00 41.86 ? 947 HOH A O 1 HETATM 4580 O O . HOH H 6 . ? -74.346 25.358 -10.847 1.00 48.78 ? 948 HOH A O 1 HETATM 4581 O O . HOH H 6 . ? -49.134 48.455 -36.204 1.00 41.95 ? 949 HOH A O 1 HETATM 4582 O O . HOH H 6 . ? -69.500 55.757 -39.513 1.00 43.48 ? 950 HOH A O 1 HETATM 4583 O O . HOH H 6 . ? -65.929 40.522 -21.642 1.00 38.94 ? 951 HOH A O 1 HETATM 4584 O O . HOH H 6 . ? -69.098 22.505 -7.726 1.00 45.07 ? 952 HOH A O 1 HETATM 4585 O O . HOH H 6 . ? -39.076 8.333 -29.206 1.00 47.56 ? 953 HOH A O 1 HETATM 4586 O O . HOH H 6 . ? -80.468 51.961 -37.597 1.00 50.70 ? 954 HOH A O 1 HETATM 4587 O O . HOH H 6 . ? -42.867 17.267 -51.748 1.00 48.04 ? 955 HOH A O 1 HETATM 4588 O O . HOH H 6 . ? -38.011 51.656 -56.142 1.00 53.43 ? 956 HOH A O 1 HETATM 4589 O O . HOH H 6 . ? -56.031 0.000 -22.840 0.50 61.52 ? 957 HOH A O 1 HETATM 4590 O O . HOH H 6 . ? -34.984 24.792 -49.381 1.00 46.61 ? 958 HOH A O 1 HETATM 4591 O O . HOH H 6 . ? -51.778 46.904 -43.680 1.00 24.02 ? 959 HOH A O 1 HETATM 4592 O O . HOH H 6 . ? -78.411 20.946 -20.785 1.00 41.83 ? 960 HOH A O 1 HETATM 4593 O O . HOH H 6 . ? -51.001 50.700 -33.758 1.00 42.92 ? 961 HOH A O 1 HETATM 4594 O O . HOH H 6 . ? -77.907 36.757 -39.524 1.00 51.66 ? 962 HOH A O 1 HETATM 4595 O O . HOH H 6 . ? -63.225 56.261 -40.797 1.00 49.22 ? 963 HOH A O 1 HETATM 4596 O O . HOH H 6 . ? -63.595 37.541 -18.817 1.00 34.16 ? 964 HOH A O 1 HETATM 4597 O O . HOH H 6 . ? -60.318 57.431 -34.847 1.00 42.64 ? 965 HOH A O 1 HETATM 4598 O O . HOH H 6 . ? -47.114 6.808 -20.297 1.00 51.54 ? 966 HOH A O 1 HETATM 4599 O O . HOH H 6 . ? -35.908 38.780 -9.804 1.00 45.45 ? 967 HOH A O 1 HETATM 4600 O O . HOH H 6 . ? -56.086 55.152 -27.918 1.00 45.72 ? 968 HOH A O 1 HETATM 4601 O O . HOH H 6 . ? -43.111 12.973 -17.761 1.00 50.62 ? 969 HOH A O 1 HETATM 4602 O O . HOH H 6 . ? -71.942 48.736 -22.298 1.00 57.66 ? 970 HOH A O 1 HETATM 4603 O O . HOH H 6 . ? -35.301 23.347 -52.078 1.00 46.69 ? 971 HOH A O 1 HETATM 4604 O O . HOH H 6 . ? -52.454 52.073 -42.736 1.00 40.08 ? 972 HOH A O 1 HETATM 4605 O O . HOH H 6 . ? -45.342 48.060 -31.351 1.00 36.71 ? 973 HOH A O 1 HETATM 4606 O O . HOH H 6 . ? -42.664 54.424 -27.204 1.00 46.43 ? 974 HOH A O 1 HETATM 4607 O O . HOH H 6 . ? -36.858 22.861 -54.441 1.00 38.51 ? 975 HOH A O 1 HETATM 4608 O O . HOH H 6 . ? -26.347 39.035 -49.207 1.00 44.78 ? 976 HOH A O 1 HETATM 4609 O O . HOH H 6 . ? -51.307 49.256 -39.931 1.00 38.61 ? 977 HOH A O 1 HETATM 4610 O O . HOH H 6 . ? -35.252 26.547 -48.118 1.00 35.69 ? 978 HOH A O 1 HETATM 4611 O O . HOH H 6 . ? -54.058 54.778 -27.637 1.00 38.29 ? 979 HOH A O 1 HETATM 4612 O O . HOH H 6 . ? -29.202 51.655 -37.209 1.00 35.12 ? 980 HOH A O 1 HETATM 4613 O O . HOH H 6 . ? -71.818 31.263 -13.309 1.00 39.44 ? 981 HOH A O 1 HETATM 4614 O O . HOH H 6 . ? -41.398 21.118 -56.197 1.00 44.00 ? 982 HOH A O 1 HETATM 4615 O O . HOH H 6 . ? -35.967 22.736 -45.261 1.00 40.63 ? 983 HOH A O 1 HETATM 4616 O O . HOH H 6 . ? -43.170 47.605 -39.756 1.00 42.22 ? 984 HOH A O 1 HETATM 4617 O O . HOH H 6 . ? -66.476 24.607 -43.860 1.00 50.90 ? 985 HOH A O 1 HETATM 4618 O O . HOH H 6 . ? -34.091 40.317 -12.546 1.00 50.16 ? 986 HOH A O 1 HETATM 4619 O O . HOH H 6 . ? -31.863 36.517 -17.066 1.00 44.26 ? 987 HOH A O 1 HETATM 4620 O O . HOH H 6 . ? -55.467 48.525 -52.783 1.00 39.58 ? 988 HOH A O 1 HETATM 4621 O O . HOH H 6 . ? -52.286 52.897 -40.111 1.00 43.30 ? 989 HOH A O 1 HETATM 4622 O O . HOH H 6 . ? -52.224 52.990 -32.288 1.00 29.91 ? 990 HOH A O 1 HETATM 4623 O O . HOH H 6 . ? -24.337 38.658 -49.869 1.00 50.31 ? 991 HOH A O 1 HETATM 4624 O O . HOH H 6 . ? -55.034 55.898 -31.256 1.00 43.57 ? 992 HOH A O 1 HETATM 4625 O O . HOH H 6 . ? -61.646 13.214 -30.194 1.00 46.77 ? 993 HOH A O 1 HETATM 4626 O O . HOH H 6 . ? -42.586 48.877 -42.385 1.00 50.63 ? 994 HOH A O 1 HETATM 4627 O O . HOH H 6 . ? -52.041 55.185 -28.563 1.00 35.46 ? 995 HOH A O 1 HETATM 4628 O O . HOH H 6 . ? -63.192 56.253 -43.288 1.00 44.87 ? 996 HOH A O 1 HETATM 4629 O O . HOH H 6 . ? -37.295 9.253 -27.532 1.00 39.55 ? 997 HOH A O 1 HETATM 4630 O O . HOH H 6 . ? -39.851 10.642 -23.657 1.00 33.61 ? 998 HOH A O 1 HETATM 4631 O O . HOH H 6 . ? -50.017 52.548 -30.731 1.00 40.17 ? 999 HOH A O 1 HETATM 4632 O O . HOH H 6 . ? -40.759 49.002 -40.638 1.00 45.17 ? 1000 HOH A O 1 HETATM 4633 O O . HOH H 6 . ? -47.969 54.836 -31.449 1.00 48.28 ? 1001 HOH A O 1 HETATM 4634 O O . HOH H 6 . ? -79.331 48.457 -44.047 1.00 48.16 ? 1002 HOH A O 1 HETATM 4635 O O . HOH H 6 . ? -25.415 36.875 -47.923 1.00 54.35 ? 1003 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ASP 1 2 2 ASP ASP A . n A 1 2 HIS 2 3 3 HIS HIS A . n A 1 3 SER 3 4 4 SER SER A . n A 1 4 GLU 4 5 5 GLU GLU A . n A 1 5 LEU 5 6 6 LEU LEU A . n A 1 6 LEU 6 7 7 LEU LEU A . n A 1 7 VAL 7 8 8 VAL VAL A . n A 1 8 ASN 8 9 9 ASN ASN A . n A 1 9 THR 9 10 10 THR THR A . n A 1 10 LYS 10 11 11 LYS LYS A . n A 1 11 SER 11 12 12 SER SER A . n A 1 12 GLY 12 13 13 GLY GLY A . n A 1 13 LYS 13 14 14 LYS LYS A . n A 1 14 VAL 14 15 15 VAL VAL A . n A 1 15 MET 15 16 16 MET MET A . n A 1 16 GLY 16 17 17 GLY GLY A . n A 1 17 THR 17 18 18 THR THR A . n A 1 18 ARG 18 19 19 ARG ARG A . n A 1 19 VAL 19 20 20 VAL VAL A . n A 1 20 PRO 20 21 21 PRO PRO A . n A 1 21 VAL 21 22 22 VAL VAL A . n A 1 22 LEU 22 23 23 LEU LEU A . n A 1 23 SER 23 24 24 SER SER A . n A 1 24 SER 24 25 25 SER SER A . n A 1 25 HIS 25 26 26 HIS HIS A . n A 1 26 ILE 26 27 27 ILE ILE A . n A 1 27 SER 27 28 28 SER SER A . n A 1 28 ALA 28 29 29 ALA ALA A . n A 1 29 PHE 29 30 30 PHE PHE A . n A 1 30 LEU 30 31 31 LEU LEU A . n A 1 31 GLY 31 32 32 GLY GLY A . n A 1 32 ILE 32 33 33 ILE ILE A . n A 1 33 PRO 33 34 34 PRO PRO A . n A 1 34 PHE 34 35 35 PHE PHE A . n A 1 35 ALA 35 36 36 ALA ALA A . n A 1 36 GLU 36 37 37 GLU GLU A . n A 1 37 PRO 37 38 38 PRO PRO A . n A 1 38 PRO 38 39 39 PRO PRO A . n A 1 39 VAL 39 40 40 VAL VAL A . n A 1 40 GLY 40 41 41 GLY GLY A . n A 1 41 ASN 41 42 42 ASN ASN A . n A 1 42 MET 42 43 43 MET MET A . n A 1 43 ARG 43 44 44 ARG ARG A . n A 1 44 PHE 44 45 45 PHE PHE A . n A 1 45 ARG 45 46 46 ARG ARG A . n A 1 46 ARG 46 47 47 ARG ARG A . n A 1 47 PRO 47 48 48 PRO PRO A . n A 1 48 GLU 48 49 49 GLU GLU A . n A 1 49 PRO 49 50 50 PRO PRO A . n A 1 50 LYS 50 51 51 LYS LYS A . n A 1 51 LYS 51 52 52 LYS LYS A . n A 1 52 PRO 52 53 53 PRO PRO A . n A 1 53 TRP 53 54 54 TRP TRP A . n A 1 54 SER 54 55 55 SER SER A . n A 1 55 GLY 55 56 56 GLY GLY A . n A 1 56 VAL 56 57 57 VAL VAL A . n A 1 57 TRP 57 58 58 TRP TRP A . n A 1 58 ASN 58 59 59 ASN ASN A . n A 1 59 ALA 59 60 60 ALA ALA A . n A 1 60 SER 60 61 61 SER SER A . n A 1 61 THR 61 62 62 THR THR A . n A 1 62 TYR 62 63 63 TYR TYR A . n A 1 63 PRO 63 64 64 PRO PRO A . n A 1 64 ASN 64 65 65 ASN ASN A . n A 1 65 ASN 65 66 66 ASN ASN A . n A 1 66 CYS 66 67 67 CYS CYS A . n A 1 67 GLN 67 68 68 GLN GLN A . n A 1 68 GLN 68 69 69 GLN GLN A . n A 1 69 TYR 69 70 70 TYR TYR A . n A 1 70 VAL 70 71 71 VAL VAL A . n A 1 71 ASP 71 72 72 ASP ASP A . n A 1 72 GLU 72 73 73 GLU GLU A . n A 1 73 GLN 73 74 74 GLN GLN A . n A 1 74 PHE 74 75 75 PHE PHE A . n A 1 75 PRO 75 76 76 PRO PRO A . n A 1 76 GLY 76 77 77 GLY GLY A . n A 1 77 PHE 77 78 78 PHE PHE A . n A 1 78 SER 78 79 79 SER SER A . n A 1 79 GLY 79 80 80 GLY GLY A . n A 1 80 SER 80 81 81 SER SER A . n A 1 81 GLU 81 82 82 GLU GLU A . n A 1 82 MET 82 83 83 MET MET A . n A 1 83 TRP 83 84 84 TRP TRP A . n A 1 84 ASN 84 85 85 ASN ASN A . n A 1 85 PRO 85 86 86 PRO PRO A . n A 1 86 ASN 86 87 87 ASN ASN A . n A 1 87 ARG 87 88 88 ARG ARG A . n A 1 88 GLU 88 89 89 GLU GLU A . n A 1 89 MET 89 90 90 MET MET A . n A 1 90 SER 90 91 91 SER SER A . n A 1 91 GLU 91 92 92 GLU GLU A . n A 1 92 ASP 92 93 93 ASP ASP A . n A 1 93 CYS 93 94 94 CYS CYS A . n A 1 94 LEU 94 95 95 LEU LEU A . n A 1 95 TYR 95 96 96 TYR TYR A . n A 1 96 LEU 96 97 97 LEU LEU A . n A 1 97 ASN 97 98 98 ASN ASN A . n A 1 98 ILE 98 99 99 ILE ILE A . n A 1 99 TRP 99 100 100 TRP TRP A . n A 1 100 VAL 100 101 101 VAL VAL A . n A 1 101 PRO 101 102 102 PRO PRO A . n A 1 102 SER 102 103 103 SER SER A . n A 1 103 PRO 103 104 104 PRO PRO A . n A 1 104 ARG 104 105 105 ARG ARG A . n A 1 105 PRO 105 106 106 PRO PRO A . n A 1 106 LYS 106 107 107 LYS LYS A . n A 1 107 SER 107 108 108 SER SER A . n A 1 108 THR 108 109 109 THR THR A . n A 1 109 THR 109 110 110 THR THR A . n A 1 110 VAL 110 111 111 VAL VAL A . n A 1 111 MET 111 112 112 MET MET A . n A 1 112 VAL 112 113 113 VAL VAL A . n A 1 113 TRP 113 114 114 TRP TRP A . n A 1 114 ILE 114 115 115 ILE ILE A . n A 1 115 TYR 115 116 116 TYR TYR A . n A 1 116 GLY 116 117 117 GLY GLY A . n A 1 117 GLY 117 118 118 GLY GLY A . n A 1 118 GLY 118 119 119 GLY GLY A . n A 1 119 PHE 119 120 120 PHE PHE A . n A 1 120 TYR 120 121 121 TYR TYR A . n A 1 121 SER 121 122 122 SER SER A . n A 1 122 GLY 122 123 123 GLY GLY A . n A 1 123 SER 123 124 124 SER SER A . n A 1 124 SER 124 125 125 SER SER A . n A 1 125 THR 125 126 126 THR THR A . n A 1 126 LEU 126 127 127 LEU LEU A . n A 1 127 ASP 127 128 128 ASP ASP A . n A 1 128 VAL 128 129 129 VAL VAL A . n A 1 129 TYR 129 130 130 TYR TYR A . n A 1 130 ASN 130 131 131 ASN ASN A . n A 1 131 GLY 131 132 132 GLY GLY A . n A 1 132 LYS 132 133 133 LYS LYS A . n A 1 133 TYR 133 134 134 TYR TYR A . n A 1 134 LEU 134 135 135 LEU LEU A . n A 1 135 ALA 135 136 136 ALA ALA A . n A 1 136 TYR 136 137 137 TYR TYR A . n A 1 137 THR 137 138 138 THR THR A . n A 1 138 GLU 138 139 139 GLU GLU A . n A 1 139 GLU 139 140 140 GLU GLU A . n A 1 140 VAL 140 141 141 VAL VAL A . n A 1 141 VAL 141 142 142 VAL VAL A . n A 1 142 LEU 142 143 143 LEU LEU A . n A 1 143 VAL 143 144 144 VAL VAL A . n A 1 144 SER 144 145 145 SER SER A . n A 1 145 LEU 145 146 146 LEU LEU A . n A 1 146 SER 146 147 147 SER SER A . n A 1 147 TYR 147 148 148 TYR TYR A . n A 1 148 ARG 148 149 149 ARG ARG A . n A 1 149 VAL 149 150 150 VAL VAL A . n A 1 150 GLY 150 151 151 GLY GLY A . n A 1 151 ALA 151 152 152 ALA ALA A . n A 1 152 PHE 152 153 153 PHE PHE A . n A 1 153 GLY 153 154 154 GLY GLY A . n A 1 154 PHE 154 155 155 PHE PHE A . n A 1 155 LEU 155 156 156 LEU LEU A . n A 1 156 ALA 156 157 157 ALA ALA A . n A 1 157 LEU 157 158 158 LEU LEU A . n A 1 158 HIS 158 159 159 HIS HIS A . n A 1 159 GLY 159 160 160 GLY GLY A . n A 1 160 SER 160 161 161 SER SER A . n A 1 161 GLN 161 162 162 GLN GLN A . n A 1 162 GLU 162 163 163 GLU GLU A . n A 1 163 ALA 163 164 164 ALA ALA A . n A 1 164 PRO 164 165 165 PRO PRO A . n A 1 165 GLY 165 166 166 GLY GLY A . n A 1 166 ASN 166 167 167 ASN ASN A . n A 1 167 VAL 167 168 168 VAL VAL A . n A 1 168 GLY 168 169 169 GLY GLY A . n A 1 169 LEU 169 170 170 LEU LEU A . n A 1 170 LEU 170 171 171 LEU LEU A . n A 1 171 ASP 171 172 172 ASP ASP A . n A 1 172 GLN 172 173 173 GLN GLN A . n A 1 173 ARG 173 174 174 ARG ARG A . n A 1 174 MET 174 175 175 MET MET A . n A 1 175 ALA 175 176 176 ALA ALA A . n A 1 176 LEU 176 177 177 LEU LEU A . n A 1 177 GLN 177 178 178 GLN GLN A . n A 1 178 TRP 178 179 179 TRP TRP A . n A 1 179 VAL 179 180 180 VAL VAL A . n A 1 180 HIS 180 181 181 HIS HIS A . n A 1 181 ASP 181 182 182 ASP ASP A . n A 1 182 ASN 182 183 183 ASN ASN A . n A 1 183 ILE 183 184 184 ILE ILE A . n A 1 184 GLN 184 185 185 GLN GLN A . n A 1 185 PHE 185 186 186 PHE PHE A . n A 1 186 PHE 186 187 187 PHE PHE A . n A 1 187 GLY 187 188 188 GLY GLY A . n A 1 188 GLY 188 189 189 GLY GLY A . n A 1 189 ASP 189 190 190 ASP ASP A . n A 1 190 PRO 190 191 191 PRO PRO A . n A 1 191 LYS 191 192 192 LYS LYS A . n A 1 192 THR 192 193 193 THR THR A . n A 1 193 VAL 193 194 194 VAL VAL A . n A 1 194 THR 194 195 195 THR THR A . n A 1 195 ILE 195 196 196 ILE ILE A . n A 1 196 PHE 196 197 197 PHE PHE A . n A 1 197 GLY 197 198 198 GLY GLY A . n A 1 198 GLU 198 199 199 GLU GLU A . n A 1 199 SER 199 200 200 SER SER A . n A 1 200 ALA 200 201 201 ALA ALA A . n A 1 201 GLY 201 202 202 GLY GLY A . n A 1 202 GLY 202 203 203 GLY GLY A . n A 1 203 ALA 203 204 204 ALA ALA A . n A 1 204 SER 204 205 205 SER SER A . n A 1 205 VAL 205 206 206 VAL VAL A . n A 1 206 GLY 206 207 207 GLY GLY A . n A 1 207 MET 207 208 208 MET MET A . n A 1 208 HIS 208 209 209 HIS HIS A . n A 1 209 ILE 209 210 210 ILE ILE A . n A 1 210 LEU 210 211 211 LEU LEU A . n A 1 211 SER 211 212 212 SER SER A . n A 1 212 PRO 212 213 213 PRO PRO A . n A 1 213 GLY 213 214 214 GLY GLY A . n A 1 214 SER 214 215 215 SER SER A . n A 1 215 ARG 215 216 216 ARG ARG A . n A 1 216 ASP 216 217 217 ASP ASP A . n A 1 217 LEU 217 218 218 LEU LEU A . n A 1 218 PHE 218 219 219 PHE PHE A . n A 1 219 ARG 219 220 220 ARG ARG A . n A 1 220 ARG 220 221 221 ARG ARG A . n A 1 221 ALA 221 222 222 ALA ALA A . n A 1 222 ILE 222 223 223 ILE ILE A . n A 1 223 LEU 223 224 224 LEU LEU A . n A 1 224 GLN 224 225 225 GLN GLN A . n A 1 225 SER 225 226 226 SER SER A . n A 1 226 GLY 226 227 227 GLY GLY A . n A 1 227 SER 227 228 228 SER SER A . n A 1 228 PRO 228 229 229 PRO PRO A . n A 1 229 ASN 229 230 230 ASN ASN A . n A 1 230 CYS 230 231 231 CYS CYS A . n A 1 231 PRO 231 232 232 PRO PRO A . n A 1 232 TRP 232 233 233 TRP TRP A . n A 1 233 ALA 233 234 234 ALA ALA A . n A 1 234 SER 234 235 235 SER SER A . n A 1 235 VAL 235 236 236 VAL VAL A . n A 1 236 SER 236 237 237 SER SER A . n A 1 237 VAL 237 238 238 VAL VAL A . n A 1 238 ALA 238 239 239 ALA ALA A . n A 1 239 GLU 239 240 240 GLU GLU A . n A 1 240 GLY 240 241 241 GLY GLY A . n A 1 241 ARG 241 242 242 ARG ARG A . n A 1 242 ARG 242 243 243 ARG ARG A . n A 1 243 ARG 243 244 244 ARG ARG A . n A 1 244 ALA 244 245 245 ALA ALA A . n A 1 245 VAL 245 246 246 VAL VAL A . n A 1 246 GLU 246 247 247 GLU GLU A . n A 1 247 LEU 247 248 248 LEU LEU A . n A 1 248 GLY 248 249 249 GLY GLY A . n A 1 249 ARG 249 250 250 ARG ARG A . n A 1 250 ASN 250 251 251 ASN ASN A . n A 1 251 LEU 251 252 252 LEU LEU A . n A 1 252 ASN 252 253 253 ASN ASN A . n A 1 253 CYS 253 254 254 CYS CYS A . n A 1 254 ASN 254 255 255 ASN ASN A . n A 1 255 LEU 255 256 256 LEU LEU A . n A 1 256 ASN 256 257 257 ASN ASN A . n A 1 257 SER 257 258 258 SER SER A . n A 1 258 ASP 258 259 259 ASP ASP A . n A 1 259 GLU 259 260 260 GLU GLU A . n A 1 260 GLU 260 261 261 GLU GLU A . n A 1 261 LEU 261 262 262 LEU LEU A . n A 1 262 ILE 262 263 263 ILE ILE A . n A 1 263 HIS 263 264 264 HIS HIS A . n A 1 264 CYS 264 265 265 CYS CYS A . n A 1 265 LEU 265 266 266 LEU LEU A . n A 1 266 ARG 266 267 267 ARG ARG A . n A 1 267 GLU 267 268 268 GLU GLU A . n A 1 268 LYS 268 269 269 LYS LYS A . n A 1 269 LYS 269 270 270 LYS LYS A . n A 1 270 PRO 270 271 271 PRO PRO A . n A 1 271 GLN 271 272 272 GLN GLN A . n A 1 272 GLU 272 273 273 GLU GLU A . n A 1 273 LEU 273 274 274 LEU LEU A . n A 1 274 ILE 274 275 275 ILE ILE A . n A 1 275 ASP 275 276 276 ASP ASP A . n A 1 276 VAL 276 277 277 VAL VAL A . n A 1 277 GLU 277 278 278 GLU GLU A . n A 1 278 TRP 278 279 279 TRP TRP A . n A 1 279 ASN 279 280 280 ASN ASN A . n A 1 280 VAL 280 281 281 VAL VAL A . n A 1 281 LEU 281 282 282 LEU LEU A . n A 1 282 PRO 282 283 283 PRO PRO A . n A 1 283 PHE 283 284 284 PHE PHE A . n A 1 284 ASP 284 285 285 ASP ASP A . n A 1 285 SER 285 286 286 SER SER A . n A 1 286 ILE 286 287 287 ILE ILE A . n A 1 287 PHE 287 288 288 PHE PHE A . n A 1 288 ARG 288 289 289 ARG ARG A . n A 1 289 PHE 289 290 290 PHE PHE A . n A 1 290 SER 290 291 291 SER SER A . n A 1 291 PHE 291 292 292 PHE PHE A . n A 1 292 VAL 292 293 293 VAL VAL A . n A 1 293 PRO 293 294 294 PRO PRO A . n A 1 294 VAL 294 295 295 VAL VAL A . n A 1 295 ILE 295 296 296 ILE ILE A . n A 1 296 ASP 296 297 297 ASP ASP A . n A 1 297 GLY 297 298 298 GLY GLY A . n A 1 298 GLU 298 299 299 GLU GLU A . n A 1 299 PHE 299 300 300 PHE PHE A . n A 1 300 PHE 300 301 301 PHE PHE A . n A 1 301 PRO 301 302 302 PRO PRO A . n A 1 302 THR 302 303 303 THR THR A . n A 1 303 SER 303 304 304 SER SER A . n A 1 304 LEU 304 305 305 LEU LEU A . n A 1 305 GLU 305 306 306 GLU GLU A . n A 1 306 SER 306 307 307 SER SER A . n A 1 307 MET 307 308 308 MET MET A . n A 1 308 LEU 308 309 309 LEU LEU A . n A 1 309 ASN 309 310 310 ASN ASN A . n A 1 310 SER 310 311 311 SER SER A . n A 1 311 GLY 311 312 312 GLY GLY A . n A 1 312 ASN 312 313 313 ASN ASN A . n A 1 313 PHE 313 314 314 PHE PHE A . n A 1 314 LYS 314 315 315 LYS LYS A . n A 1 315 LYS 315 316 316 LYS LYS A . n A 1 316 THR 316 317 317 THR THR A . n A 1 317 GLN 317 318 318 GLN GLN A . n A 1 318 ILE 318 319 319 ILE ILE A . n A 1 319 LEU 319 320 320 LEU LEU A . n A 1 320 LEU 320 321 321 LEU LEU A . n A 1 321 GLY 321 322 322 GLY GLY A . n A 1 322 VAL 322 323 323 VAL VAL A . n A 1 323 ASN 323 324 324 ASN ASN A . n A 1 324 LYS 324 325 325 LYS LYS A . n A 1 325 ASP 325 326 326 ASP ASP A . n A 1 326 GLU 326 327 327 GLU GLU A . n A 1 327 GLY 327 328 328 GLY GLY A . n A 1 328 SER 328 329 329 SER SER A . n A 1 329 PHE 329 330 330 PHE PHE A . n A 1 330 PHE 330 331 331 PHE PHE A . n A 1 331 LEU 331 332 332 LEU LEU A . n A 1 332 LEU 332 333 333 LEU LEU A . n A 1 333 TYR 333 334 334 TYR TYR A . n A 1 334 GLY 334 335 335 GLY GLY A . n A 1 335 ALA 335 336 336 ALA ALA A . n A 1 336 PRO 336 337 337 PRO PRO A . n A 1 337 GLY 337 338 338 GLY GLY A . n A 1 338 PHE 338 339 339 PHE PHE A . n A 1 339 SER 339 340 340 SER SER A . n A 1 340 LYS 340 341 341 LYS LYS A . n A 1 341 ASP 341 342 342 ASP ASP A . n A 1 342 SER 342 343 343 SER SER A . n A 1 343 GLU 343 344 344 GLU GLU A . n A 1 344 SER 344 345 345 SER SER A . n A 1 345 LYS 345 346 346 LYS LYS A . n A 1 346 ILE 346 347 347 ILE ILE A . n A 1 347 SER 347 348 348 SER SER A . n A 1 348 ARG 348 349 349 ARG ARG A . n A 1 349 GLU 349 350 350 GLU GLU A . n A 1 350 ASP 350 351 351 ASP ASP A . n A 1 351 PHE 351 352 352 PHE PHE A . n A 1 352 MET 352 353 353 MET MET A . n A 1 353 SER 353 354 354 SER SER A . n A 1 354 GLY 354 355 355 GLY GLY A . n A 1 355 VAL 355 356 356 VAL VAL A . n A 1 356 LYS 356 357 357 LYS LYS A . n A 1 357 LEU 357 358 358 LEU LEU A . n A 1 358 SER 358 359 359 SER SER A . n A 1 359 VAL 359 360 360 VAL VAL A . n A 1 360 PRO 360 361 361 PRO PRO A . n A 1 361 HIS 361 362 362 HIS HIS A . n A 1 362 ALA 362 363 363 ALA ALA A . n A 1 363 ASN 363 364 364 ASN ASN A . n A 1 364 ASP 364 365 365 ASP ASP A . n A 1 365 LEU 365 366 366 LEU LEU A . n A 1 366 GLY 366 367 367 GLY GLY A . n A 1 367 LEU 367 368 368 LEU LEU A . n A 1 368 ASP 368 369 369 ASP ASP A . n A 1 369 ALA 369 370 370 ALA ALA A . n A 1 370 VAL 370 371 371 VAL VAL A . n A 1 371 THR 371 372 372 THR THR A . n A 1 372 LEU 372 373 373 LEU LEU A . n A 1 373 GLN 373 374 374 GLN GLN A . n A 1 374 TYR 374 375 375 TYR TYR A . n A 1 375 THR 375 376 376 THR THR A . n A 1 376 ASP 376 377 377 ASP ASP A . n A 1 377 TRP 377 378 378 TRP TRP A . n A 1 378 MET 378 379 379 MET MET A . n A 1 379 ASP 379 380 380 ASP ASP A . n A 1 380 ASP 380 381 381 ASP ASP A . n A 1 381 ASN 381 382 382 ASN ASN A . n A 1 382 ASN 382 383 383 ASN ASN A . n A 1 383 GLY 383 384 384 GLY GLY A . n A 1 384 ILE 384 385 385 ILE ILE A . n A 1 385 LYS 385 386 386 LYS LYS A . n A 1 386 ASN 386 387 387 ASN ASN A . n A 1 387 ARG 387 388 388 ARG ARG A . n A 1 388 ASP 388 389 389 ASP ASP A . n A 1 389 GLY 389 390 390 GLY GLY A . n A 1 390 LEU 390 391 391 LEU LEU A . n A 1 391 ASP 391 392 392 ASP ASP A . n A 1 392 ASP 392 393 393 ASP ASP A . n A 1 393 ILE 393 394 394 ILE ILE A . n A 1 394 VAL 394 395 395 VAL VAL A . n A 1 395 GLY 395 396 396 GLY GLY A . n A 1 396 ASP 396 397 397 ASP ASP A . n A 1 397 HIS 397 398 398 HIS HIS A . n A 1 398 ASN 398 399 399 ASN ASN A . n A 1 399 VAL 399 400 400 VAL VAL A . n A 1 400 ILE 400 401 401 ILE ILE A . n A 1 401 CYS 401 402 402 CYS CYS A . n A 1 402 PRO 402 403 403 PRO PRO A . n A 1 403 LEU 403 404 404 LEU LEU A . n A 1 404 MET 404 405 405 MET MET A . n A 1 405 HIS 405 406 406 HIS HIS A . n A 1 406 PHE 406 407 407 PHE PHE A . n A 1 407 VAL 407 408 408 VAL VAL A . n A 1 408 ASN 408 409 409 ASN ASN A . n A 1 409 LYS 409 410 410 LYS LYS A . n A 1 410 TYR 410 411 411 TYR TYR A . n A 1 411 THR 411 412 412 THR THR A . n A 1 412 LYS 412 413 413 LYS LYS A . n A 1 413 PHE 413 414 414 PHE PHE A . n A 1 414 GLY 414 415 415 GLY GLY A . n A 1 415 ASN 415 416 416 ASN ASN A . n A 1 416 GLY 416 417 417 GLY GLY A . n A 1 417 THR 417 418 418 THR THR A . n A 1 418 TYR 418 419 419 TYR TYR A . n A 1 419 LEU 419 420 420 LEU LEU A . n A 1 420 TYR 420 421 421 TYR TYR A . n A 1 421 PHE 421 422 422 PHE PHE A . n A 1 422 PHE 422 423 423 PHE PHE A . n A 1 423 ASN 423 424 424 ASN ASN A . n A 1 424 HIS 424 425 425 HIS HIS A . n A 1 425 ARG 425 426 426 ARG ARG A . n A 1 426 ALA 426 427 427 ALA ALA A . n A 1 427 SER 427 428 428 SER SER A . n A 1 428 ASN 428 429 429 ASN ASN A . n A 1 429 LEU 429 430 430 LEU LEU A . n A 1 430 VAL 430 431 431 VAL VAL A . n A 1 431 TRP 431 432 432 TRP TRP A . n A 1 432 PRO 432 433 433 PRO PRO A . n A 1 433 GLU 433 434 434 GLU GLU A . n A 1 434 TRP 434 435 435 TRP TRP A . n A 1 435 MET 435 436 436 MET MET A . n A 1 436 GLY 436 437 437 GLY GLY A . n A 1 437 VAL 437 438 438 VAL VAL A . n A 1 438 ILE 438 439 439 ILE ILE A . n A 1 439 HIS 439 440 440 HIS HIS A . n A 1 440 GLY 440 441 441 GLY GLY A . n A 1 441 TYR 441 442 442 TYR TYR A . n A 1 442 GLU 442 443 443 GLU GLU A . n A 1 443 ILE 443 444 444 ILE ILE A . n A 1 444 GLU 444 445 445 GLU GLU A . n A 1 445 PHE 445 446 446 PHE PHE A . n A 1 446 VAL 446 447 447 VAL VAL A . n A 1 447 PHE 447 448 448 PHE PHE A . n A 1 448 GLY 448 449 449 GLY GLY A . n A 1 449 LEU 449 450 450 LEU LEU A . n A 1 450 PRO 450 451 451 PRO PRO A . n A 1 451 LEU 451 452 452 LEU LEU A . n A 1 452 VAL 452 453 453 VAL VAL A . n A 1 453 LYS 453 454 454 LYS LYS A . n A 1 454 GLU 454 455 455 GLU GLU A . n A 1 455 LEU 455 456 456 LEU LEU A . n A 1 456 ASN 456 457 457 ASN ASN A . n A 1 457 TYR 457 458 458 TYR TYR A . n A 1 458 THR 458 459 459 THR THR A . n A 1 459 ALA 459 460 460 ALA ALA A . n A 1 460 GLU 460 461 461 GLU GLU A . n A 1 461 GLU 461 462 462 GLU GLU A . n A 1 462 GLU 462 463 463 GLU GLU A . n A 1 463 ALA 463 464 464 ALA ALA A . n A 1 464 LEU 464 465 465 LEU LEU A . n A 1 465 SER 465 466 466 SER SER A . n A 1 466 ARG 466 467 467 ARG ARG A . n A 1 467 ARG 467 468 468 ARG ARG A . n A 1 468 ILE 468 469 469 ILE ILE A . n A 1 469 MET 469 470 470 MET MET A . n A 1 470 HIS 470 471 471 HIS HIS A . n A 1 471 TYR 471 472 472 TYR TYR A . n A 1 472 TRP 472 473 473 TRP TRP A . n A 1 473 ALA 473 474 474 ALA ALA A . n A 1 474 THR 474 475 475 THR THR A . n A 1 475 PHE 475 476 476 PHE PHE A . n A 1 476 ALA 476 477 477 ALA ALA A . n A 1 477 LYS 477 478 478 LYS LYS A . n A 1 478 THR 478 479 479 THR THR A . n A 1 479 GLY 479 480 480 GLY GLY A . n A 1 480 ASN 480 481 481 ASN ASN A . n A 1 481 PRO 481 482 482 PRO PRO A . n A 1 482 ASN 482 483 483 ASN ASN A . n A 1 483 GLU 483 484 484 GLU GLU A . n A 1 484 PRO 484 485 485 PRO PRO A . n A 1 485 HIS 485 486 486 HIS HIS A . n A 1 486 SER 486 487 487 SER SER A . n A 1 487 GLN 487 488 488 GLN GLN A . n A 1 488 GLU 488 489 489 GLU GLU A . n A 1 489 SER 489 490 490 SER SER A . n A 1 490 LYS 490 491 491 LYS LYS A . n A 1 491 TRP 491 492 492 TRP TRP A . n A 1 492 PRO 492 493 493 PRO PRO A . n A 1 493 LEU 493 494 494 LEU LEU A . n A 1 494 PHE 494 495 495 PHE PHE A . n A 1 495 THR 495 496 496 THR THR A . n A 1 496 THR 496 497 497 THR THR A . n A 1 497 LYS 497 498 498 LYS LYS A . n A 1 498 GLU 498 499 499 GLU GLU A . n A 1 499 GLN 499 500 500 GLN GLN A . n A 1 500 LYS 500 501 501 LYS LYS A . n A 1 501 PHE 501 502 502 PHE PHE A . n A 1 502 ILE 502 503 503 ILE ILE A . n A 1 503 ASP 503 504 504 ASP ASP A . n A 1 504 LEU 504 505 505 LEU LEU A . n A 1 505 ASN 505 506 506 ASN ASN A . n A 1 506 THR 506 507 507 THR THR A . n A 1 507 GLU 507 508 508 GLU GLU A . n A 1 508 PRO 508 509 509 PRO PRO A . n A 1 509 MET 509 510 510 MET MET A . n A 1 510 LYS 510 511 511 LYS LYS A . n A 1 511 VAL 511 512 512 VAL VAL A . n A 1 512 HIS 512 513 513 HIS HIS A . n A 1 513 GLN 513 514 514 GLN GLN A . n A 1 514 ARG 514 515 515 ARG ARG A . n A 1 515 LEU 515 516 516 LEU LEU A . n A 1 516 ARG 516 517 517 ARG ARG A . n A 1 517 VAL 517 518 518 VAL VAL A . n A 1 518 GLN 518 519 519 GLN GLN A . n A 1 519 MET 519 520 520 MET MET A . n A 1 520 CYS 520 521 521 CYS CYS A . n A 1 521 VAL 521 522 522 VAL VAL A . n A 1 522 PHE 522 523 523 PHE PHE A . n A 1 523 TRP 523 524 524 TRP TRP A . n A 1 524 ASN 524 525 525 ASN ASN A . n A 1 525 GLN 525 526 526 GLN GLN A . n A 1 526 PHE 526 527 527 PHE PHE A . n A 1 527 LEU 527 528 528 LEU LEU A . n A 1 528 PRO 528 529 529 PRO PRO A . n A 1 529 LYS 529 530 530 LYS LYS A . n A 1 530 LEU 530 531 531 LEU LEU A . n A 1 531 LEU 531 532 532 LEU LEU A . n A 1 532 ASN 532 533 533 ASN ASN A . n A 1 533 ALA 533 534 534 ALA ALA A . n A 1 534 THR 534 535 535 THR THR A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 601 601 NAG NAG A . C 2 NAG 1 602 602 NAG NAG A . D 2 NAG 2 603 603 NAG NAG A . E 3 OMI 1 604 604 OMI OMI A . F 4 PG4 1 605 605 PG4 PG4 A . G 5 ACT 1 606 606 ACT ACT A . H 6 HOH 1 701 701 HOH HOH A . H 6 HOH 2 702 702 HOH HOH A . H 6 HOH 3 703 703 HOH HOH A . H 6 HOH 4 704 704 HOH HOH A . H 6 HOH 5 705 705 HOH HOH A . H 6 HOH 6 706 706 HOH HOH A . H 6 HOH 7 707 707 HOH HOH A . H 6 HOH 8 708 708 HOH HOH A . H 6 HOH 9 709 709 HOH HOH A . H 6 HOH 10 710 710 HOH HOH A . H 6 HOH 11 711 711 HOH HOH A . H 6 HOH 12 712 712 HOH HOH A . H 6 HOH 13 713 713 HOH HOH A . H 6 HOH 14 714 714 HOH HOH A . H 6 HOH 15 715 715 HOH HOH A . H 6 HOH 16 716 716 HOH HOH A . H 6 HOH 17 717 717 HOH HOH A . H 6 HOH 18 718 718 HOH HOH A . H 6 HOH 19 719 719 HOH HOH A . H 6 HOH 20 720 720 HOH HOH A . H 6 HOH 21 721 721 HOH HOH A . H 6 HOH 22 722 722 HOH HOH A . H 6 HOH 23 723 723 HOH HOH A . H 6 HOH 24 724 724 HOH HOH A . H 6 HOH 25 725 725 HOH HOH A . H 6 HOH 26 726 726 HOH HOH A . H 6 HOH 27 727 727 HOH HOH A . H 6 HOH 28 728 728 HOH HOH A . H 6 HOH 29 729 729 HOH HOH A . H 6 HOH 30 730 730 HOH HOH A . H 6 HOH 31 731 731 HOH HOH A . H 6 HOH 32 732 732 HOH HOH A . H 6 HOH 33 733 733 HOH HOH A . H 6 HOH 34 734 734 HOH HOH A . H 6 HOH 35 735 735 HOH HOH A . H 6 HOH 36 736 736 HOH HOH A . H 6 HOH 37 737 737 HOH HOH A . H 6 HOH 38 738 738 HOH HOH A . H 6 HOH 39 739 739 HOH HOH A . H 6 HOH 40 740 740 HOH HOH A . H 6 HOH 41 741 741 HOH HOH A . H 6 HOH 42 742 742 HOH HOH A . H 6 HOH 43 743 743 HOH HOH A . H 6 HOH 44 744 744 HOH HOH A . H 6 HOH 45 745 745 HOH HOH A . H 6 HOH 46 746 746 HOH HOH A . H 6 HOH 47 747 747 HOH HOH A . H 6 HOH 48 748 748 HOH HOH A . H 6 HOH 49 749 749 HOH HOH A . H 6 HOH 50 750 750 HOH HOH A . H 6 HOH 51 751 751 HOH HOH A . H 6 HOH 52 752 752 HOH HOH A . H 6 HOH 53 753 753 HOH HOH A . H 6 HOH 54 754 754 HOH HOH A . H 6 HOH 55 755 755 HOH HOH A . H 6 HOH 56 756 756 HOH HOH A . H 6 HOH 57 757 757 HOH HOH A . H 6 HOH 58 758 758 HOH HOH A . H 6 HOH 59 759 759 HOH HOH A . H 6 HOH 60 760 760 HOH HOH A . H 6 HOH 61 761 761 HOH HOH A . H 6 HOH 62 762 762 HOH HOH A . H 6 HOH 63 763 763 HOH HOH A . H 6 HOH 64 764 764 HOH HOH A . H 6 HOH 65 765 765 HOH HOH A . H 6 HOH 66 766 766 HOH HOH A . H 6 HOH 67 767 767 HOH HOH A . H 6 HOH 68 768 768 HOH HOH A . H 6 HOH 69 769 769 HOH HOH A . H 6 HOH 70 770 770 HOH HOH A . H 6 HOH 71 771 771 HOH HOH A . H 6 HOH 72 772 772 HOH HOH A . H 6 HOH 73 773 773 HOH HOH A . H 6 HOH 74 774 774 HOH HOH A . H 6 HOH 75 775 775 HOH HOH A . H 6 HOH 76 776 776 HOH HOH A . H 6 HOH 77 777 777 HOH HOH A . H 6 HOH 78 778 778 HOH HOH A . H 6 HOH 79 779 779 HOH HOH A . H 6 HOH 80 780 780 HOH HOH A . H 6 HOH 81 781 781 HOH HOH A . H 6 HOH 82 782 782 HOH HOH A . H 6 HOH 83 783 783 HOH HOH A . H 6 HOH 84 784 784 HOH HOH A . H 6 HOH 85 785 785 HOH HOH A . H 6 HOH 86 786 786 HOH HOH A . H 6 HOH 87 787 787 HOH HOH A . H 6 HOH 88 788 788 HOH HOH A . H 6 HOH 89 789 789 HOH HOH A . H 6 HOH 90 790 790 HOH HOH A . H 6 HOH 91 791 791 HOH HOH A . H 6 HOH 92 792 792 HOH HOH A . H 6 HOH 93 793 793 HOH HOH A . H 6 HOH 94 794 794 HOH HOH A . H 6 HOH 95 795 795 HOH HOH A . H 6 HOH 96 796 796 HOH HOH A . H 6 HOH 97 797 797 HOH HOH A . H 6 HOH 98 798 798 HOH HOH A . H 6 HOH 99 799 799 HOH HOH A . H 6 HOH 100 800 800 HOH HOH A . H 6 HOH 101 801 801 HOH HOH A . H 6 HOH 102 802 802 HOH HOH A . H 6 HOH 103 803 803 HOH HOH A . H 6 HOH 104 804 804 HOH HOH A . H 6 HOH 105 805 805 HOH HOH A . H 6 HOH 106 806 806 HOH HOH A . H 6 HOH 107 807 807 HOH HOH A . H 6 HOH 108 808 808 HOH HOH A . H 6 HOH 109 809 809 HOH HOH A . H 6 HOH 110 810 810 HOH HOH A . H 6 HOH 111 811 811 HOH HOH A . H 6 HOH 112 812 812 HOH HOH A . H 6 HOH 113 813 813 HOH HOH A . H 6 HOH 114 814 814 HOH HOH A . H 6 HOH 115 815 815 HOH HOH A . H 6 HOH 116 816 816 HOH HOH A . H 6 HOH 117 817 817 HOH HOH A . H 6 HOH 118 818 818 HOH HOH A . H 6 HOH 119 819 819 HOH HOH A . H 6 HOH 120 820 820 HOH HOH A . H 6 HOH 121 821 821 HOH HOH A . H 6 HOH 122 822 822 HOH HOH A . H 6 HOH 123 823 823 HOH HOH A . H 6 HOH 124 824 824 HOH HOH A . H 6 HOH 125 825 825 HOH HOH A . H 6 HOH 126 826 826 HOH HOH A . H 6 HOH 127 827 827 HOH HOH A . H 6 HOH 128 828 828 HOH HOH A . H 6 HOH 129 829 829 HOH HOH A . H 6 HOH 130 830 830 HOH HOH A . H 6 HOH 131 831 831 HOH HOH A . H 6 HOH 132 832 832 HOH HOH A . H 6 HOH 133 833 833 HOH HOH A . H 6 HOH 134 834 834 HOH HOH A . H 6 HOH 135 835 835 HOH HOH A . H 6 HOH 136 836 836 HOH HOH A . H 6 HOH 137 837 837 HOH HOH A . H 6 HOH 138 838 838 HOH HOH A . H 6 HOH 139 839 839 HOH HOH A . H 6 HOH 140 840 840 HOH HOH A . H 6 HOH 141 841 841 HOH HOH A . H 6 HOH 142 842 842 HOH HOH A . H 6 HOH 143 843 843 HOH HOH A . H 6 HOH 144 844 844 HOH HOH A . H 6 HOH 145 845 845 HOH HOH A . H 6 HOH 146 846 846 HOH HOH A . H 6 HOH 147 847 847 HOH HOH A . H 6 HOH 148 848 848 HOH HOH A . H 6 HOH 149 849 849 HOH HOH A . H 6 HOH 150 850 850 HOH HOH A . H 6 HOH 151 851 851 HOH HOH A . H 6 HOH 152 852 852 HOH HOH A . H 6 HOH 153 853 853 HOH HOH A . H 6 HOH 154 854 854 HOH HOH A . H 6 HOH 155 855 855 HOH HOH A . H 6 HOH 156 856 856 HOH HOH A . H 6 HOH 157 857 857 HOH HOH A . H 6 HOH 158 858 858 HOH HOH A . H 6 HOH 159 859 859 HOH HOH A . H 6 HOH 160 860 860 HOH HOH A . H 6 HOH 161 861 861 HOH HOH A . H 6 HOH 162 862 862 HOH HOH A . H 6 HOH 163 863 863 HOH HOH A . H 6 HOH 164 864 864 HOH HOH A . H 6 HOH 165 865 865 HOH HOH A . H 6 HOH 166 866 866 HOH HOH A . H 6 HOH 167 867 867 HOH HOH A . H 6 HOH 168 868 868 HOH HOH A . H 6 HOH 169 869 869 HOH HOH A . H 6 HOH 170 870 870 HOH HOH A . H 6 HOH 171 871 871 HOH HOH A . H 6 HOH 172 872 872 HOH HOH A . H 6 HOH 173 873 873 HOH HOH A . H 6 HOH 174 874 874 HOH HOH A . H 6 HOH 175 875 875 HOH HOH A . H 6 HOH 176 876 876 HOH HOH A . H 6 HOH 177 877 877 HOH HOH A . H 6 HOH 178 878 878 HOH HOH A . H 6 HOH 179 879 879 HOH HOH A . H 6 HOH 180 880 880 HOH HOH A . H 6 HOH 181 881 881 HOH HOH A . H 6 HOH 182 882 882 HOH HOH A . H 6 HOH 183 883 883 HOH HOH A . H 6 HOH 184 884 884 HOH HOH A . H 6 HOH 185 885 885 HOH HOH A . H 6 HOH 186 886 886 HOH HOH A . H 6 HOH 187 887 887 HOH HOH A . H 6 HOH 188 888 888 HOH HOH A . H 6 HOH 189 889 889 HOH HOH A . H 6 HOH 190 890 890 HOH HOH A . H 6 HOH 191 891 891 HOH HOH A . H 6 HOH 192 892 892 HOH HOH A . H 6 HOH 193 893 893 HOH HOH A . H 6 HOH 194 894 894 HOH HOH A . H 6 HOH 195 895 895 HOH HOH A . H 6 HOH 196 896 896 HOH HOH A . H 6 HOH 197 897 897 HOH HOH A . H 6 HOH 198 898 898 HOH HOH A . H 6 HOH 199 899 899 HOH HOH A . H 6 HOH 200 900 900 HOH HOH A . H 6 HOH 201 901 901 HOH HOH A . H 6 HOH 202 902 902 HOH HOH A . H 6 HOH 203 903 903 HOH HOH A . H 6 HOH 204 904 904 HOH HOH A . H 6 HOH 205 905 905 HOH HOH A . H 6 HOH 206 906 906 HOH HOH A . H 6 HOH 207 907 907 HOH HOH A . H 6 HOH 208 908 908 HOH HOH A . H 6 HOH 209 909 909 HOH HOH A . H 6 HOH 210 910 910 HOH HOH A . H 6 HOH 211 911 911 HOH HOH A . H 6 HOH 212 912 912 HOH HOH A . H 6 HOH 213 913 913 HOH HOH A . H 6 HOH 214 914 914 HOH HOH A . H 6 HOH 215 915 915 HOH HOH A . H 6 HOH 216 916 916 HOH HOH A . H 6 HOH 217 917 917 HOH HOH A . H 6 HOH 218 918 918 HOH HOH A . H 6 HOH 219 919 919 HOH HOH A . H 6 HOH 220 920 920 HOH HOH A . H 6 HOH 221 921 921 HOH HOH A . H 6 HOH 222 922 922 HOH HOH A . H 6 HOH 223 923 923 HOH HOH A . H 6 HOH 224 924 924 HOH HOH A . H 6 HOH 225 925 925 HOH HOH A . H 6 HOH 226 926 926 HOH HOH A . H 6 HOH 227 927 927 HOH HOH A . H 6 HOH 228 928 928 HOH HOH A . H 6 HOH 229 929 929 HOH HOH A . H 6 HOH 230 930 930 HOH HOH A . H 6 HOH 231 931 931 HOH HOH A . H 6 HOH 232 932 932 HOH HOH A . H 6 HOH 233 933 933 HOH HOH A . H 6 HOH 234 934 934 HOH HOH A . H 6 HOH 235 935 935 HOH HOH A . H 6 HOH 236 936 936 HOH HOH A . H 6 HOH 237 937 937 HOH HOH A . H 6 HOH 238 938 938 HOH HOH A . H 6 HOH 239 939 939 HOH HOH A . H 6 HOH 240 940 940 HOH HOH A . H 6 HOH 241 941 941 HOH HOH A . H 6 HOH 242 942 942 HOH HOH A . H 6 HOH 243 943 943 HOH HOH A . H 6 HOH 244 944 944 HOH HOH A . H 6 HOH 245 945 945 HOH HOH A . H 6 HOH 246 946 946 HOH HOH A . H 6 HOH 247 947 947 HOH HOH A . H 6 HOH 248 948 948 HOH HOH A . H 6 HOH 249 949 949 HOH HOH A . H 6 HOH 250 950 950 HOH HOH A . H 6 HOH 251 951 951 HOH HOH A . H 6 HOH 252 952 952 HOH HOH A . H 6 HOH 253 953 953 HOH HOH A . H 6 HOH 254 954 954 HOH HOH A . H 6 HOH 255 955 955 HOH HOH A . H 6 HOH 256 956 956 HOH HOH A . H 6 HOH 257 957 957 HOH HOH A . H 6 HOH 258 958 958 HOH HOH A . H 6 HOH 259 959 959 HOH HOH A . H 6 HOH 260 960 960 HOH HOH A . H 6 HOH 261 961 961 HOH HOH A . H 6 HOH 262 962 962 HOH HOH A . H 6 HOH 263 963 963 HOH HOH A . H 6 HOH 264 964 964 HOH HOH A . H 6 HOH 265 965 965 HOH HOH A . H 6 HOH 266 966 966 HOH HOH A . H 6 HOH 267 967 967 HOH HOH A . H 6 HOH 268 968 968 HOH HOH A . H 6 HOH 269 969 969 HOH HOH A . H 6 HOH 270 970 970 HOH HOH A . H 6 HOH 271 971 971 HOH HOH A . H 6 HOH 272 972 972 HOH HOH A . H 6 HOH 273 973 973 HOH HOH A . H 6 HOH 274 974 974 HOH HOH A . H 6 HOH 275 975 975 HOH HOH A . H 6 HOH 276 976 976 HOH HOH A . H 6 HOH 277 977 977 HOH HOH A . H 6 HOH 278 978 978 HOH HOH A . H 6 HOH 279 979 979 HOH HOH A . H 6 HOH 280 980 980 HOH HOH A . H 6 HOH 281 981 981 HOH HOH A . H 6 HOH 282 982 982 HOH HOH A . H 6 HOH 283 983 983 HOH HOH A . H 6 HOH 284 984 984 HOH HOH A . H 6 HOH 285 985 985 HOH HOH A . H 6 HOH 286 986 986 HOH HOH A . H 6 HOH 287 987 987 HOH HOH A . H 6 HOH 288 988 988 HOH HOH A . H 6 HOH 289 989 989 HOH HOH A . H 6 HOH 290 990 990 HOH HOH A . H 6 HOH 291 991 991 HOH HOH A . H 6 HOH 292 992 992 HOH HOH A . H 6 HOH 293 993 993 HOH HOH A . H 6 HOH 294 994 994 HOH HOH A . H 6 HOH 295 995 995 HOH HOH A . H 6 HOH 296 996 996 HOH HOH A . H 6 HOH 297 997 997 HOH HOH A . H 6 HOH 298 998 998 HOH HOH A . H 6 HOH 299 999 999 HOH HOH A . H 6 HOH 300 1000 1000 HOH HOH A . H 6 HOH 301 1001 1001 HOH HOH A . H 6 HOH 302 1002 1002 HOH HOH A . H 6 HOH 303 1003 1003 HOH HOH A . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1,2 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 3540 ? 1 MORE -3 ? 1 'SSA (A^2)' 41060 ? # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 6_554 -x,-x+y,-z-2/3 -0.5000000000 -0.8660254038 0.0000000000 0.0000000000 -0.8660254038 0.5000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 -91.3666666667 # _pdbx_struct_special_symmetry.id 1 _pdbx_struct_special_symmetry.PDB_model_num 1 _pdbx_struct_special_symmetry.auth_asym_id A _pdbx_struct_special_symmetry.auth_comp_id HOH _pdbx_struct_special_symmetry.auth_seq_id 957 _pdbx_struct_special_symmetry.PDB_ins_code ? _pdbx_struct_special_symmetry.label_asym_id H _pdbx_struct_special_symmetry.label_comp_id HOH _pdbx_struct_special_symmetry.label_seq_id . # _pdbx_audit_revision_history.ordinal 1 _pdbx_audit_revision_history.data_content_type 'Structure model' _pdbx_audit_revision_history.major_revision 1 _pdbx_audit_revision_history.minor_revision 0 _pdbx_audit_revision_history.revision_date 2017-04-05 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.7.0032 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? MOSFLM ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? SCALA ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? . 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 O A HOH 968 ? ? O A HOH 979 ? ? 2.08 2 1 O A HOH 976 ? ? O A HOH 991 ? ? 2.15 3 1 O A HOH 882 ? ? O A HOH 1002 ? ? 2.18 4 1 O A HOH 958 ? ? O A HOH 978 ? ? 2.18 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 CB _pdbx_validate_rmsd_bond.auth_asym_id_1 A _pdbx_validate_rmsd_bond.auth_comp_id_1 HIS _pdbx_validate_rmsd_bond.auth_seq_id_1 3 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 ? _pdbx_validate_rmsd_bond.auth_atom_id_2 CG _pdbx_validate_rmsd_bond.auth_asym_id_2 A _pdbx_validate_rmsd_bond.auth_comp_id_2 HIS _pdbx_validate_rmsd_bond.auth_seq_id_2 3 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 ? _pdbx_validate_rmsd_bond.bond_value 1.206 _pdbx_validate_rmsd_bond.bond_target_value 1.492 _pdbx_validate_rmsd_bond.bond_deviation -0.286 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.016 _pdbx_validate_rmsd_bond.linker_flag N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CA A ASP 2 ? ? CB A ASP 2 ? ? CG A ASP 2 ? ? 156.06 113.40 42.66 2.20 N 2 1 CB A ASP 2 ? ? CG A ASP 2 ? ? OD1 A ASP 2 ? ? 98.38 118.30 -19.92 0.90 N 3 1 CB A ASP 2 ? ? CG A ASP 2 ? ? OD2 A ASP 2 ? ? 131.23 118.30 12.93 0.90 N 4 1 CA A HIS 3 ? ? CB A HIS 3 ? ? CG A HIS 3 ? ? 124.89 113.60 11.29 1.70 N 5 1 CB A HIS 3 ? ? CG A HIS 3 ? ? CD2 A HIS 3 ? ? 139.37 131.40 7.97 1.20 N 6 1 CB A ASP 93 ? ? CG A ASP 93 ? ? OD1 A ASP 93 ? ? 124.85 118.30 6.55 0.90 N 7 1 CB A ASP 93 ? ? CG A ASP 93 ? ? OD2 A ASP 93 ? ? 112.30 118.30 -6.00 0.90 N 8 1 NE A ARG 174 ? ? CZ A ARG 174 ? ? NH1 A ARG 174 ? ? 123.63 120.30 3.33 0.50 N 9 1 NE A ARG 221 ? ? CZ A ARG 221 ? ? NH1 A ARG 221 ? ? 123.40 120.30 3.10 0.50 N 10 1 NE A ARG 221 ? ? CZ A ARG 221 ? ? NH2 A ARG 221 ? ? 115.86 120.30 -4.44 0.50 N 11 1 NE A ARG 243 ? ? CZ A ARG 243 ? ? NH1 A ARG 243 ? ? 124.03 120.30 3.73 0.50 N 12 1 NE A ARG 243 ? ? CZ A ARG 243 ? ? NH2 A ARG 243 ? ? 115.94 120.30 -4.36 0.50 N 13 1 NE A ARG 388 ? ? CZ A ARG 388 ? ? NH1 A ARG 388 ? ? 124.20 120.30 3.90 0.50 N 14 1 NE A ARG 388 ? ? CZ A ARG 388 ? ? NH2 A ARG 388 ? ? 116.09 120.30 -4.21 0.50 N 15 1 NE A ARG 426 ? ? CZ A ARG 426 ? ? NH1 A ARG 426 ? ? 123.91 120.30 3.61 0.50 N 16 1 CB A VAL 518 ? ? CA A VAL 518 ? ? C A VAL 518 ? ? 97.04 111.40 -14.36 1.90 N 17 1 CG1 A VAL 518 ? ? CB A VAL 518 ? ? CG2 A VAL 518 ? ? 121.71 110.90 10.81 1.60 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 VAL A 22 ? ? -160.03 116.85 2 1 SER A 25 ? ? -161.88 -164.29 3 1 PHE A 45 ? ? 77.45 -10.24 4 1 CYS A 94 ? ? -143.62 10.21 5 1 PRO A 102 ? ? -48.71 155.66 6 1 SER A 108 ? ? -154.38 71.71 7 1 LEU A 158 ? ? -112.12 78.97 8 1 SER A 200 ? ? 58.42 -117.38 9 1 GLU A 299 ? ? -125.56 -74.73 10 1 THR A 317 ? ? -162.72 -158.99 11 1 ASP A 380 ? ? -158.87 64.16 12 1 VAL A 400 ? ? -129.81 -58.35 13 1 ARG A 515 ? ? 60.09 63.63 14 1 GLN A 526 ? ? -122.95 -51.77 # _pdbx_validate_planes.id 1 _pdbx_validate_planes.PDB_model_num 1 _pdbx_validate_planes.auth_comp_id ASP _pdbx_validate_planes.auth_asym_id A _pdbx_validate_planes.auth_seq_id 2 _pdbx_validate_planes.PDB_ins_code ? _pdbx_validate_planes.label_alt_id ? _pdbx_validate_planes.rmsd 0.087 _pdbx_validate_planes.type 'SIDE CHAIN' # _pdbx_distant_solvent_atoms.id 1 _pdbx_distant_solvent_atoms.PDB_model_num 1 _pdbx_distant_solvent_atoms.auth_atom_id O _pdbx_distant_solvent_atoms.label_alt_id ? _pdbx_distant_solvent_atoms.auth_asym_id A _pdbx_distant_solvent_atoms.auth_comp_id HOH _pdbx_distant_solvent_atoms.auth_seq_id 1003 _pdbx_distant_solvent_atoms.PDB_ins_code ? _pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 5.93 _pdbx_distant_solvent_atoms.neighbor_ligand_distance . # _pdbx_unobs_or_zero_occ_atoms.id 1 _pdbx_unobs_or_zero_occ_atoms.PDB_model_num 1 _pdbx_unobs_or_zero_occ_atoms.polymer_flag N _pdbx_unobs_or_zero_occ_atoms.occupancy_flag 1 _pdbx_unobs_or_zero_occ_atoms.auth_asym_id A _pdbx_unobs_or_zero_occ_atoms.auth_comp_id PG4 _pdbx_unobs_or_zero_occ_atoms.auth_seq_id 605 _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code ? _pdbx_unobs_or_zero_occ_atoms.auth_atom_id O1 _pdbx_unobs_or_zero_occ_atoms.label_alt_id ? _pdbx_unobs_or_zero_occ_atoms.label_asym_id F _pdbx_unobs_or_zero_occ_atoms.label_comp_id PG4 _pdbx_unobs_or_zero_occ_atoms.label_seq_id 1 _pdbx_unobs_or_zero_occ_atoms.label_atom_id O1 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 1-methyl-1,2-dihydro-3H-indol-3-one OMI 4 'TETRAETHYLENE GLYCOL' PG4 5 'ACETATE ION' ACT 6 water HOH #