data_5IEF # _entry.id 5IEF # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5IEF WWPDB D_1000218726 # loop_ _pdbx_database_related.content_type _pdbx_database_related.db_id _pdbx_database_related.db_name _pdbx_database_related.details unspecified 5F0E PDB . unspecified 5HJO PDB . unspecified 5HJR PDB . unspecified 5H9O PDB . unspecified 5IED PDB . unspecified 5IEE PDB . unspecified 5IEG PDB . # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5IEF _pdbx_database_status.recvd_initial_deposition_date 2016-02-25 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBE _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Caputo, A.T.' 1 'Roversi, P.' 2 'Alonzi, D.S.' 3 'Kiappes, J.L.' 4 'Zitzmann, N.' 5 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev Proc.Natl.Acad.Sci.USA _citation.journal_id_ASTM PNASA6 _citation.journal_id_CSD 0040 _citation.journal_id_ISSN 1091-6490 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 113 _citation.language ? _citation.page_first E4630 _citation.page_last E4638 _citation.title 'Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.' _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1073/pnas.1604463113 _citation.pdbx_database_id_PubMed 27462106 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Caputo, A.T.' 1 primary 'Alonzi, D.S.' 2 primary 'Marti, L.' 3 primary 'Reca, I.B.' 4 primary 'Kiappes, J.L.' 5 primary 'Struwe, W.B.' 6 primary 'Cross, A.' 7 primary 'Basu, S.' 8 primary 'Lowe, E.D.' 9 primary 'Darlot, B.' 10 primary 'Santino, A.' 11 primary 'Roversi, P.' 12 primary 'Zitzmann, N.' 13 # _cell.angle_alpha 90.00 _cell.angle_alpha_esd ? _cell.angle_beta 90.00 _cell.angle_beta_esd ? _cell.angle_gamma 90.00 _cell.angle_gamma_esd ? _cell.entry_id 5IEF _cell.details ? _cell.formula_units_Z ? _cell.length_a 103.840 _cell.length_a_esd ? _cell.length_b 172.890 _cell.length_b_esd ? _cell.length_c 62.770 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 4 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 5IEF _symmetry.cell_setting ? _symmetry.Int_Tables_number 18 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'P 21 21 2' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Neutral alpha-glucosidase AB' 103731.891 1 3.2.1.84 ? ? ;This chain contains all of the residues from the mature Q8BHN3 isoform 2 (i.e. no signal peptide and starts at residue 33) but has been trypsinised so that there are two gaps in the sequence between: 186-243 and 351-369 (inclusive) ; 2 polymer man 'Glucosidase 2 subunit beta' 9568.298 1 ? ? ? ;This chain contains all of the residues from the mature O08795 but has been trypsinised so that there all that was crystallised are residues: 30-117 ; 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 2 ? ? ? ? 4 non-polymer syn 'FORMIC ACID' 46.025 1 ? ? ? ? 5 non-polymer syn 'ACETATE ION' 59.044 1 ? ? ? ? 6 non-polymer syn '(2R,3R,4R,5S)-1-BUTYL-2-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL' 219.278 1 ? ? ? ? 7 non-polymer syn 'HEXAETHYLENE GLYCOL' 282.331 2 ? ? ? ? 8 non-polymer syn 'CALCIUM ION' 40.078 2 ? ? ? ? 9 water nat water 18.015 290 ? ? ? ? # loop_ _entity_name_com.entity_id _entity_name_com.name 1 'Alpha-glucosidase 2,Glucosidase II subunit alpha' 2 '80K-H protein,Glucosidase II subunit beta,Protein kinase C substrate 60.1 kDa protein heavy chain,PKCSH' # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPR YRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKD PAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTD IRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEH ADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSG GIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPF FRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFV ALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPE SRLSFQHDPETSVLILRKPGVSVASDWSIHLRA ; ;VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPR YRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKD PAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTE GGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTD IRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEH ADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDF TNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSG GIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPF FRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDAL LIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFV ALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPE SRLSFQHDPETSVLILRKPGVSVASDWSIHLRA ; A ? 2 'polypeptide(L)' no no ;FYEESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSG TVCENTCR ; ;FYEESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSG TVCENTCR ; B ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 VAL n 1 2 ASP n 1 3 ARG n 1 4 SER n 1 5 ASN n 1 6 PHE n 1 7 LYS n 1 8 THR n 1 9 CYS n 1 10 ASP n 1 11 GLU n 1 12 SER n 1 13 SER n 1 14 PHE n 1 15 CYS n 1 16 LYS n 1 17 ARG n 1 18 GLN n 1 19 ARG n 1 20 SER n 1 21 ILE n 1 22 ARG n 1 23 PRO n 1 24 GLY n 1 25 LEU n 1 26 SER n 1 27 PRO n 1 28 TYR n 1 29 ARG n 1 30 ALA n 1 31 LEU n 1 32 LEU n 1 33 ASP n 1 34 THR n 1 35 LEU n 1 36 GLN n 1 37 LEU n 1 38 GLY n 1 39 PRO n 1 40 ASP n 1 41 ALA n 1 42 LEU n 1 43 THR n 1 44 VAL n 1 45 HIS n 1 46 LEU n 1 47 ILE n 1 48 HIS n 1 49 GLU n 1 50 VAL n 1 51 THR n 1 52 LYS n 1 53 VAL n 1 54 LEU n 1 55 LEU n 1 56 VAL n 1 57 LEU n 1 58 GLU n 1 59 LEU n 1 60 GLN n 1 61 GLY n 1 62 LEU n 1 63 GLN n 1 64 LYS n 1 65 ASN n 1 66 MET n 1 67 THR n 1 68 ARG n 1 69 ILE n 1 70 ARG n 1 71 ILE n 1 72 ASP n 1 73 GLU n 1 74 LEU n 1 75 GLU n 1 76 PRO n 1 77 ARG n 1 78 ARG n 1 79 PRO n 1 80 ARG n 1 81 TYR n 1 82 ARG n 1 83 VAL n 1 84 PRO n 1 85 ASP n 1 86 VAL n 1 87 LEU n 1 88 VAL n 1 89 ALA n 1 90 ASP n 1 91 PRO n 1 92 PRO n 1 93 THR n 1 94 ALA n 1 95 ARG n 1 96 LEU n 1 97 SER n 1 98 VAL n 1 99 SER n 1 100 GLY n 1 101 ARG n 1 102 ASP n 1 103 ASP n 1 104 ASN n 1 105 SER n 1 106 VAL n 1 107 GLU n 1 108 LEU n 1 109 THR n 1 110 VAL n 1 111 ALA n 1 112 GLU n 1 113 GLY n 1 114 PRO n 1 115 TYR n 1 116 LYS n 1 117 ILE n 1 118 ILE n 1 119 LEU n 1 120 THR n 1 121 ALA n 1 122 GLN n 1 123 PRO n 1 124 PHE n 1 125 ARG n 1 126 LEU n 1 127 ASP n 1 128 LEU n 1 129 LEU n 1 130 GLU n 1 131 ASP n 1 132 ARG n 1 133 SER n 1 134 LEU n 1 135 LEU n 1 136 LEU n 1 137 SER n 1 138 VAL n 1 139 ASN n 1 140 ALA n 1 141 ARG n 1 142 GLY n 1 143 LEU n 1 144 MET n 1 145 ALA n 1 146 PHE n 1 147 GLU n 1 148 HIS n 1 149 GLN n 1 150 ARG n 1 151 ALA n 1 152 PRO n 1 153 ARG n 1 154 VAL n 1 155 PRO n 1 156 GLN n 1 157 GLU n 1 158 SER n 1 159 LYS n 1 160 ASP n 1 161 PRO n 1 162 ALA n 1 163 GLU n 1 164 GLY n 1 165 ASN n 1 166 GLY n 1 167 ALA n 1 168 GLN n 1 169 PRO n 1 170 GLU n 1 171 ALA n 1 172 THR n 1 173 PRO n 1 174 GLY n 1 175 ASP n 1 176 GLY n 1 177 ASP n 1 178 LYS n 1 179 PRO n 1 180 GLU n 1 181 GLU n 1 182 THR n 1 183 GLN n 1 184 GLU n 1 185 LYS n 1 186 ALA n 1 187 GLU n 1 188 LYS n 1 189 ASP n 1 190 GLU n 1 191 PRO n 1 192 GLY n 1 193 ALA n 1 194 TRP n 1 195 GLU n 1 196 GLU n 1 197 THR n 1 198 PHE n 1 199 LYS n 1 200 THR n 1 201 HIS n 1 202 SER n 1 203 ASP n 1 204 SER n 1 205 LYS n 1 206 PRO n 1 207 TYR n 1 208 GLY n 1 209 PRO n 1 210 THR n 1 211 SER n 1 212 VAL n 1 213 GLY n 1 214 LEU n 1 215 ASP n 1 216 PHE n 1 217 SER n 1 218 LEU n 1 219 PRO n 1 220 GLY n 1 221 MET n 1 222 GLU n 1 223 HIS n 1 224 VAL n 1 225 TYR n 1 226 GLY n 1 227 ILE n 1 228 PRO n 1 229 GLU n 1 230 HIS n 1 231 ALA n 1 232 ASP n 1 233 SER n 1 234 LEU n 1 235 ARG n 1 236 LEU n 1 237 LYS n 1 238 VAL n 1 239 THR n 1 240 GLU n 1 241 GLY n 1 242 GLY n 1 243 GLU n 1 244 PRO n 1 245 TYR n 1 246 ARG n 1 247 LEU n 1 248 TYR n 1 249 ASN n 1 250 LEU n 1 251 ASP n 1 252 VAL n 1 253 PHE n 1 254 GLN n 1 255 TYR n 1 256 GLU n 1 257 LEU n 1 258 ASN n 1 259 ASN n 1 260 PRO n 1 261 MET n 1 262 ALA n 1 263 LEU n 1 264 TYR n 1 265 GLY n 1 266 SER n 1 267 VAL n 1 268 PRO n 1 269 VAL n 1 270 LEU n 1 271 LEU n 1 272 ALA n 1 273 HIS n 1 274 SER n 1 275 PHE n 1 276 HIS n 1 277 ARG n 1 278 ASP n 1 279 LEU n 1 280 GLY n 1 281 ILE n 1 282 PHE n 1 283 TRP n 1 284 LEU n 1 285 ASN n 1 286 ALA n 1 287 ALA n 1 288 GLU n 1 289 THR n 1 290 TRP n 1 291 VAL n 1 292 ASP n 1 293 ILE n 1 294 SER n 1 295 SER n 1 296 ASN n 1 297 THR n 1 298 ALA n 1 299 GLY n 1 300 LYS n 1 301 THR n 1 302 LEU n 1 303 PHE n 1 304 GLY n 1 305 LYS n 1 306 MET n 1 307 LEU n 1 308 ASP n 1 309 TYR n 1 310 LEU n 1 311 GLN n 1 312 GLY n 1 313 SER n 1 314 GLY n 1 315 GLU n 1 316 THR n 1 317 PRO n 1 318 GLN n 1 319 THR n 1 320 ASP n 1 321 ILE n 1 322 ARG n 1 323 TRP n 1 324 MET n 1 325 SER n 1 326 GLU n 1 327 SER n 1 328 GLY n 1 329 ILE n 1 330 ILE n 1 331 ASP n 1 332 VAL n 1 333 PHE n 1 334 LEU n 1 335 MET n 1 336 LEU n 1 337 GLY n 1 338 PRO n 1 339 SER n 1 340 VAL n 1 341 PHE n 1 342 ASP n 1 343 VAL n 1 344 PHE n 1 345 ARG n 1 346 GLN n 1 347 TYR n 1 348 ALA n 1 349 SER n 1 350 LEU n 1 351 THR n 1 352 GLY n 1 353 THR n 1 354 GLN n 1 355 ALA n 1 356 LEU n 1 357 PRO n 1 358 PRO n 1 359 LEU n 1 360 PHE n 1 361 SER n 1 362 LEU n 1 363 GLY n 1 364 TYR n 1 365 HIS n 1 366 GLN n 1 367 SER n 1 368 ARG n 1 369 TRP n 1 370 ASN n 1 371 TYR n 1 372 ARG n 1 373 ASP n 1 374 GLU n 1 375 ALA n 1 376 ASP n 1 377 VAL n 1 378 LEU n 1 379 GLU n 1 380 VAL n 1 381 ASP n 1 382 GLN n 1 383 GLY n 1 384 PHE n 1 385 ASP n 1 386 ASP n 1 387 HIS n 1 388 ASN n 1 389 MET n 1 390 PRO n 1 391 CYS n 1 392 ASP n 1 393 VAL n 1 394 ILE n 1 395 TRP n 1 396 LEU n 1 397 ASP n 1 398 ILE n 1 399 GLU n 1 400 HIS n 1 401 ALA n 1 402 ASP n 1 403 GLY n 1 404 LYS n 1 405 ARG n 1 406 TYR n 1 407 PHE n 1 408 THR n 1 409 TRP n 1 410 ASP n 1 411 PRO n 1 412 THR n 1 413 ARG n 1 414 PHE n 1 415 PRO n 1 416 GLN n 1 417 PRO n 1 418 LEU n 1 419 ASN n 1 420 MET n 1 421 LEU n 1 422 GLU n 1 423 HIS n 1 424 LEU n 1 425 ALA n 1 426 SER n 1 427 LYS n 1 428 ARG n 1 429 ARG n 1 430 LYS n 1 431 LEU n 1 432 VAL n 1 433 ALA n 1 434 ILE n 1 435 VAL n 1 436 ASP n 1 437 PRO n 1 438 HIS n 1 439 ILE n 1 440 LYS n 1 441 VAL n 1 442 ASP n 1 443 SER n 1 444 GLY n 1 445 TYR n 1 446 ARG n 1 447 VAL n 1 448 HIS n 1 449 GLU n 1 450 GLU n 1 451 LEU n 1 452 ARG n 1 453 ASN n 1 454 HIS n 1 455 GLY n 1 456 LEU n 1 457 TYR n 1 458 VAL n 1 459 LYS n 1 460 THR n 1 461 ARG n 1 462 ASP n 1 463 GLY n 1 464 SER n 1 465 ASP n 1 466 TYR n 1 467 GLU n 1 468 GLY n 1 469 TRP n 1 470 CYS n 1 471 TRP n 1 472 PRO n 1 473 GLY n 1 474 SER n 1 475 ALA n 1 476 SER n 1 477 TYR n 1 478 PRO n 1 479 ASP n 1 480 PHE n 1 481 THR n 1 482 ASN n 1 483 PRO n 1 484 ARG n 1 485 MET n 1 486 ARG n 1 487 ALA n 1 488 TRP n 1 489 TRP n 1 490 SER n 1 491 ASN n 1 492 MET n 1 493 PHE n 1 494 SER n 1 495 PHE n 1 496 ASP n 1 497 ASN n 1 498 TYR n 1 499 GLU n 1 500 GLY n 1 501 SER n 1 502 ALA n 1 503 PRO n 1 504 ASN n 1 505 LEU n 1 506 TYR n 1 507 VAL n 1 508 TRP n 1 509 ASN n 1 510 ASP n 1 511 MET n 1 512 ASN n 1 513 GLU n 1 514 PRO n 1 515 SER n 1 516 VAL n 1 517 PHE n 1 518 ASN n 1 519 GLY n 1 520 PRO n 1 521 GLU n 1 522 VAL n 1 523 THR n 1 524 MET n 1 525 LEU n 1 526 LYS n 1 527 ASP n 1 528 ALA n 1 529 VAL n 1 530 HIS n 1 531 TYR n 1 532 GLY n 1 533 GLY n 1 534 TRP n 1 535 GLU n 1 536 HIS n 1 537 ARG n 1 538 ASP n 1 539 ILE n 1 540 HIS n 1 541 ASN n 1 542 ILE n 1 543 TYR n 1 544 GLY n 1 545 LEU n 1 546 TYR n 1 547 VAL n 1 548 HIS n 1 549 MET n 1 550 ALA n 1 551 THR n 1 552 ALA n 1 553 ASP n 1 554 GLY n 1 555 LEU n 1 556 ILE n 1 557 GLN n 1 558 ARG n 1 559 SER n 1 560 GLY n 1 561 GLY n 1 562 ILE n 1 563 GLU n 1 564 ARG n 1 565 PRO n 1 566 PHE n 1 567 VAL n 1 568 LEU n 1 569 SER n 1 570 ARG n 1 571 ALA n 1 572 PHE n 1 573 PHE n 1 574 SER n 1 575 GLY n 1 576 SER n 1 577 GLN n 1 578 ARG n 1 579 PHE n 1 580 GLY n 1 581 ALA n 1 582 VAL n 1 583 TRP n 1 584 THR n 1 585 GLY n 1 586 ASP n 1 587 ASN n 1 588 THR n 1 589 ALA n 1 590 GLU n 1 591 TRP n 1 592 ASP n 1 593 HIS n 1 594 LEU n 1 595 LYS n 1 596 ILE n 1 597 SER n 1 598 ILE n 1 599 PRO n 1 600 MET n 1 601 CYS n 1 602 LEU n 1 603 SER n 1 604 LEU n 1 605 ALA n 1 606 LEU n 1 607 VAL n 1 608 GLY n 1 609 LEU n 1 610 SER n 1 611 PHE n 1 612 CYS n 1 613 GLY n 1 614 ALA n 1 615 ASP n 1 616 VAL n 1 617 GLY n 1 618 GLY n 1 619 PHE n 1 620 PHE n 1 621 LYS n 1 622 ASN n 1 623 PRO n 1 624 GLU n 1 625 PRO n 1 626 GLU n 1 627 LEU n 1 628 LEU n 1 629 VAL n 1 630 ARG n 1 631 TRP n 1 632 TYR n 1 633 GLN n 1 634 MET n 1 635 GLY n 1 636 ALA n 1 637 TYR n 1 638 GLN n 1 639 PRO n 1 640 PHE n 1 641 PHE n 1 642 ARG n 1 643 ALA n 1 644 HIS n 1 645 ALA n 1 646 HIS n 1 647 LEU n 1 648 ASP n 1 649 THR n 1 650 GLY n 1 651 ARG n 1 652 ARG n 1 653 GLU n 1 654 PRO n 1 655 TRP n 1 656 LEU n 1 657 LEU n 1 658 ALA n 1 659 SER n 1 660 GLN n 1 661 TYR n 1 662 GLN n 1 663 ASP n 1 664 ALA n 1 665 ILE n 1 666 ARG n 1 667 ASP n 1 668 ALA n 1 669 LEU n 1 670 PHE n 1 671 GLN n 1 672 ARG n 1 673 TYR n 1 674 SER n 1 675 LEU n 1 676 LEU n 1 677 PRO n 1 678 PHE n 1 679 TRP n 1 680 TYR n 1 681 THR n 1 682 LEU n 1 683 PHE n 1 684 TYR n 1 685 GLN n 1 686 ALA n 1 687 HIS n 1 688 LYS n 1 689 GLU n 1 690 GLY n 1 691 PHE n 1 692 PRO n 1 693 VAL n 1 694 MET n 1 695 ARG n 1 696 PRO n 1 697 LEU n 1 698 TRP n 1 699 VAL n 1 700 GLN n 1 701 TYR n 1 702 PRO n 1 703 GLU n 1 704 ASP n 1 705 MET n 1 706 SER n 1 707 THR n 1 708 PHE n 1 709 SER n 1 710 ILE n 1 711 GLU n 1 712 ASP n 1 713 GLN n 1 714 PHE n 1 715 MET n 1 716 LEU n 1 717 GLY n 1 718 ASP n 1 719 ALA n 1 720 LEU n 1 721 LEU n 1 722 ILE n 1 723 HIS n 1 724 PRO n 1 725 VAL n 1 726 SER n 1 727 ASP n 1 728 ALA n 1 729 GLY n 1 730 ALA n 1 731 HIS n 1 732 GLY n 1 733 VAL n 1 734 GLN n 1 735 VAL n 1 736 TYR n 1 737 LEU n 1 738 PRO n 1 739 GLY n 1 740 GLN n 1 741 GLU n 1 742 GLU n 1 743 VAL n 1 744 TRP n 1 745 TYR n 1 746 ASP n 1 747 ILE n 1 748 GLN n 1 749 SER n 1 750 TYR n 1 751 GLN n 1 752 LYS n 1 753 HIS n 1 754 HIS n 1 755 GLY n 1 756 PRO n 1 757 GLN n 1 758 THR n 1 759 LEU n 1 760 TYR n 1 761 LEU n 1 762 PRO n 1 763 VAL n 1 764 THR n 1 765 LEU n 1 766 SER n 1 767 SER n 1 768 ILE n 1 769 PRO n 1 770 VAL n 1 771 PHE n 1 772 GLN n 1 773 ARG n 1 774 GLY n 1 775 GLY n 1 776 THR n 1 777 ILE n 1 778 VAL n 1 779 PRO n 1 780 ARG n 1 781 TRP n 1 782 MET n 1 783 ARG n 1 784 VAL n 1 785 ARG n 1 786 ARG n 1 787 SER n 1 788 SER n 1 789 ASP n 1 790 CYS n 1 791 MET n 1 792 LYS n 1 793 ASP n 1 794 ASP n 1 795 PRO n 1 796 ILE n 1 797 THR n 1 798 LEU n 1 799 PHE n 1 800 VAL n 1 801 ALA n 1 802 LEU n 1 803 SER n 1 804 PRO n 1 805 GLN n 1 806 GLY n 1 807 THR n 1 808 ALA n 1 809 GLN n 1 810 GLY n 1 811 GLU n 1 812 LEU n 1 813 PHE n 1 814 LEU n 1 815 ASP n 1 816 ASP n 1 817 GLY n 1 818 HIS n 1 819 THR n 1 820 PHE n 1 821 ASN n 1 822 TYR n 1 823 GLN n 1 824 THR n 1 825 ARG n 1 826 HIS n 1 827 GLU n 1 828 PHE n 1 829 LEU n 1 830 LEU n 1 831 ARG n 1 832 ARG n 1 833 PHE n 1 834 SER n 1 835 PHE n 1 836 SER n 1 837 GLY n 1 838 SER n 1 839 THR n 1 840 LEU n 1 841 VAL n 1 842 SER n 1 843 SER n 1 844 SER n 1 845 ALA n 1 846 ASP n 1 847 PRO n 1 848 LYS n 1 849 GLY n 1 850 HIS n 1 851 LEU n 1 852 GLU n 1 853 THR n 1 854 PRO n 1 855 ILE n 1 856 TRP n 1 857 ILE n 1 858 GLU n 1 859 ARG n 1 860 VAL n 1 861 VAL n 1 862 ILE n 1 863 MET n 1 864 GLY n 1 865 ALA n 1 866 GLY n 1 867 LYS n 1 868 PRO n 1 869 ALA n 1 870 ALA n 1 871 VAL n 1 872 VAL n 1 873 LEU n 1 874 GLN n 1 875 THR n 1 876 LYS n 1 877 GLY n 1 878 SER n 1 879 PRO n 1 880 GLU n 1 881 SER n 1 882 ARG n 1 883 LEU n 1 884 SER n 1 885 PHE n 1 886 GLN n 1 887 HIS n 1 888 ASP n 1 889 PRO n 1 890 GLU n 1 891 THR n 1 892 SER n 1 893 VAL n 1 894 LEU n 1 895 ILE n 1 896 LEU n 1 897 ARG n 1 898 LYS n 1 899 PRO n 1 900 GLY n 1 901 VAL n 1 902 SER n 1 903 VAL n 1 904 ALA n 1 905 SER n 1 906 ASP n 1 907 TRP n 1 908 SER n 1 909 ILE n 1 910 HIS n 1 911 LEU n 1 912 ARG n 1 913 ALA n 2 1 PHE n 2 2 TYR n 2 3 GLU n 2 4 GLU n 2 5 SER n 2 6 LYS n 2 7 PRO n 2 8 PHE n 2 9 THR n 2 10 CYS n 2 11 LEU n 2 12 ASP n 2 13 GLY n 2 14 THR n 2 15 ALA n 2 16 THR n 2 17 ILE n 2 18 PRO n 2 19 PHE n 2 20 ASP n 2 21 GLN n 2 22 VAL n 2 23 ASN n 2 24 ASP n 2 25 ASP n 2 26 TYR n 2 27 CYS n 2 28 ASP n 2 29 CYS n 2 30 LYS n 2 31 ASP n 2 32 GLY n 2 33 SER n 2 34 ASP n 2 35 GLU n 2 36 PRO n 2 37 GLY n 2 38 THR n 2 39 ALA n 2 40 ALA n 2 41 CYS n 2 42 PRO n 2 43 ASN n 2 44 GLY n 2 45 SER n 2 46 PHE n 2 47 HIS n 2 48 CYS n 2 49 THR n 2 50 ASN n 2 51 THR n 2 52 GLY n 2 53 TYR n 2 54 LYS n 2 55 PRO n 2 56 LEU n 2 57 TYR n 2 58 ILE n 2 59 LEU n 2 60 SER n 2 61 SER n 2 62 ARG n 2 63 VAL n 2 64 ASN n 2 65 ASP n 2 66 GLY n 2 67 VAL n 2 68 CYS n 2 69 ASP n 2 70 CYS n 2 71 CYS n 2 72 ASP n 2 73 GLY n 2 74 THR n 2 75 ASP n 2 76 GLU n 2 77 TYR n 2 78 ASN n 2 79 SER n 2 80 GLY n 2 81 THR n 2 82 VAL n 2 83 CYS n 2 84 GLU n 2 85 ASN n 2 86 THR n 2 87 CYS n 2 88 ARG n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 913 Mouse ? 'Ganab, G2an, Kiaa0088' ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? KIDNEY ? ? ? ? ? 'HEK 293-F' ? ? ENDOTHELIAL ? ? PLASMID ? ? ? pOPINGS ? ? 2 1 sample 'Biological sequence' 1 88 Mouse ? Prkcsh ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? human 'Homo sapiens' 9606 ? ? KIDNEY ? ? ? ? ? 'HEK 293-F' ? ? ENDOTHELIAL ? ? PLASMID ? ? ? pOPING ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP GANAB_MOUSE Q8BHN3 Q8BHN3-2 1 ;VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPR YRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPFSDKV SLALGSVWDKIKNLFSRQESKDPAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSL PGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTA GKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVL EVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYV KTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRD IHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGG FFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLW VQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIV PRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIE RVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPGVSVASDWSIHLR ; 33 2 UNP GLU2B_MOUSE O08795 O08795-2 2 ;FYEESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSG TVCENTCR ; 30 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5IEF A 1 ? 912 ? Q8BHN3 33 ? 966 ? 33 966 2 2 5IEF B 1 ? 88 ? O08795 30 ? 117 ? 30 117 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 5IEF ? A ? ? UNP Q8BHN3 PHE 188 deletion ? 1 1 5IEF ? A ? ? UNP Q8BHN3 SER 189 deletion ? 2 1 5IEF ? A ? ? UNP Q8BHN3 ASP 190 deletion ? 3 1 5IEF ? A ? ? UNP Q8BHN3 LYS 191 deletion ? 4 1 5IEF ? A ? ? UNP Q8BHN3 VAL 192 deletion ? 5 1 5IEF ? A ? ? UNP Q8BHN3 SER 193 deletion ? 6 1 5IEF ? A ? ? UNP Q8BHN3 LEU 194 deletion ? 7 1 5IEF ? A ? ? UNP Q8BHN3 ALA 195 deletion ? 8 1 5IEF ? A ? ? UNP Q8BHN3 LEU 196 deletion ? 9 1 5IEF ? A ? ? UNP Q8BHN3 GLY 197 deletion ? 10 1 5IEF ? A ? ? UNP Q8BHN3 SER 198 deletion ? 11 1 5IEF ? A ? ? UNP Q8BHN3 VAL 199 deletion ? 12 1 5IEF ? A ? ? UNP Q8BHN3 TRP 200 deletion ? 13 1 5IEF ? A ? ? UNP Q8BHN3 ASP 201 deletion ? 14 1 5IEF ? A ? ? UNP Q8BHN3 LYS 202 deletion ? 15 1 5IEF ? A ? ? UNP Q8BHN3 ILE 203 deletion ? 16 1 5IEF ? A ? ? UNP Q8BHN3 LYS 204 deletion ? 17 1 5IEF ? A ? ? UNP Q8BHN3 ASN 205 deletion ? 18 1 5IEF ? A ? ? UNP Q8BHN3 LEU 206 deletion ? 19 1 5IEF ? A ? ? UNP Q8BHN3 PHE 207 deletion ? 20 1 5IEF ? A ? ? UNP Q8BHN3 SER 208 deletion ? 21 1 5IEF ? A ? ? UNP Q8BHN3 ARG 209 deletion ? 22 1 5IEF ALA A 913 ? UNP Q8BHN3 ? ? 'expression tag' 967 23 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ACT non-polymer . 'ACETATE ION' ? 'C2 H3 O2 -1' 59.044 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CA non-polymer . 'CALCIUM ION' ? 'Ca 2' 40.078 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FMT non-polymer . 'FORMIC ACID' ? 'C H2 O2' 46.025 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 NBV non-polymer . '(2R,3R,4R,5S)-1-BUTYL-2-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL' ? 'C10 H21 N O4' 219.278 P6G non-polymer . 'HEXAETHYLENE GLYCOL' 'POLYETHYLENE GLYCOL PEG400' 'C12 H26 O7' 282.331 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5IEF _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.62 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 53.05 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details ;21% v/v ethylene glycol, 11% w/v PEG 8000 (from the Morpheus Precipitant Mix 2), 50 mM Morpheus carboxylic acids mix, 100 mM Morpheus buffer system 1 pH 6.25 ; _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'MARMOSAIC 225 mm CCD' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2015-11-17 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9788 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'ESRF BEAMLINE BM14' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.9788 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline BM14 _diffrn_source.pdbx_synchrotron_site ESRF # _reflns.B_iso_Wilson_estimate 38.75 _reflns.entry_id 5IEF _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.38 _reflns.d_resolution_low 103.84 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 44500 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 95.9 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 4.9 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value 0.381 _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 5.6 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half 0.960 _reflns.pdbx_R_split ? # _reflns_shell.d_res_high 2.38 _reflns_shell.d_res_low 2.51 _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs 0.9 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all 99.8 _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs ? _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy 5.0 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? # _refine.aniso_B[1][1] -0.0251 _refine.aniso_B[1][2] 0.0000 _refine.aniso_B[1][3] 0.0000 _refine.aniso_B[2][2] -1.2987 _refine.aniso_B[2][3] 0.0000 _refine.aniso_B[3][3] 1.3238 _refine.B_iso_max ? _refine.B_iso_mean 31.77 _refine.B_iso_min ? _refine.correlation_coeff_Fo_to_Fc 0.9283 _refine.correlation_coeff_Fo_to_Fc_free 0.9041 _refine.details ? _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 5IEF _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 2.38 _refine.ls_d_res_low 53.72 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 44118 _refine.ls_number_reflns_R_free 2224 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 95.50 _refine.ls_percent_reflns_R_free 5.04 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.1875 _refine.ls_R_factor_R_free 0.2176 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.1859 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details ? _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.0 _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_method_to_determine_struct 'FOURIER SYNTHESIS' _refine.pdbx_starting_model 5F0E _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI 0.223 _refine.pdbx_overall_SU_R_free_Blow_DPI 0.223 _refine.pdbx_overall_SU_R_Blow_DPI 0.378 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B ? _refine.overall_SU_ML ? _refine.overall_SU_R_Cruickshank_DPI 0.369 _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_analyze.entry_id 5IEF _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_analyze.Luzzati_coordinate_error_free ? _refine_analyze.Luzzati_coordinate_error_obs 0.318 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_sigma_a_free ? _refine_analyze.Luzzati_sigma_a_free_details ? _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_sigma_a_obs_details ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.RG_d_res_high ? _refine_analyze.RG_d_res_low ? _refine_analyze.RG_free ? _refine_analyze.RG_work ? _refine_analyze.RG_free_work_ratio ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id 1 _refine_hist.pdbx_number_atoms_protein 7627 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 85 _refine_hist.number_atoms_solvent 290 _refine_hist.number_atoms_total 8002 _refine_hist.d_res_high 2.38 _refine_hist.d_res_low 53.72 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? 0.010 ? 8056 ? t_bond_d 2.00 HARMONIC 'X-RAY DIFFRACTION' ? 1.10 ? 11023 ? t_angle_deg 2.00 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 2713 ? t_dihedral_angle_d 2.00 SINUSOIDAL 'X-RAY DIFFRACTION' ? ? ? ? ? t_incorr_chiral_ct ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_pseud_angle ? ? 'X-RAY DIFFRACTION' ? ? ? 189 ? t_trig_c_planes 2.00 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 1175 ? t_gen_planes 5.00 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 8056 ? t_it 20.00 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 0 ? t_nbd 5.00 SEMIHARMONIC 'X-RAY DIFFRACTION' ? 4.63 ? ? ? t_omega_torsion ? ? 'X-RAY DIFFRACTION' ? 15.94 ? ? ? t_other_torsion ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_improper_torsion ? ? 'X-RAY DIFFRACTION' ? ? ? 986 ? t_chiral_improper_torsion 5.00 SEMIHARMONIC 'X-RAY DIFFRACTION' ? ? ? ? ? t_sum_occupancies ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_utility_distance ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_utility_angle ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_utility_torsion ? ? 'X-RAY DIFFRACTION' ? ? ? 9288 ? t_ideal_dist_contact 4.00 SEMIHARMONIC # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.d_res_high 2.38 _refine_ls_shell.d_res_low 2.44 _refine_ls_shell.number_reflns_all 3297 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.number_reflns_R_free 149 _refine_ls_shell.number_reflns_R_work 3148 _refine_ls_shell.percent_reflns_obs 97.90 _refine_ls_shell.percent_reflns_R_free 4.52 _refine_ls_shell.R_factor_all 0.2212 _refine_ls_shell.R_factor_obs ? _refine_ls_shell.R_factor_R_free 0.2331 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.R_factor_R_work 0.2206 _refine_ls_shell.redundancy_reflns_all ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.wR_factor_all ? _refine_ls_shell.wR_factor_obs ? _refine_ls_shell.wR_factor_R_free ? _refine_ls_shell.wR_factor_R_work ? _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.pdbx_phase_error ? _refine_ls_shell.pdbx_fsc_work ? _refine_ls_shell.pdbx_fsc_free ? # _struct.entry_id 5IEF _struct.title 'Murine endoplasmic reticulum alpha-glucosidase II with N-butyl-1-deoxynojirimycin' _struct.pdbx_descriptor 'Neutral alpha-glucosidase AB (E.C.3.2.1.84), Glucosidase 2 subunit beta' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5IEF _struct_keywords.text 'Enzyme Glycosyl hydrolase GH31 Quality control exoglycosidase, hydrolase, NB-DNJ' _struct_keywords.pdbx_keywords HYDROLASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 3 ? E N N 4 ? F N N 5 ? G N N 6 ? H N N 7 ? I N N 7 ? J N N 8 ? K N N 8 ? L N N 9 ? M N N 9 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 ASP A 2 ? PHE A 6 ? ASP A 34 PHE A 38 5 ? 5 HELX_P HELX_P2 AA2 THR A 8 ? GLU A 11 ? THR A 40 GLU A 43 5 ? 4 HELX_P HELX_P3 AA3 SER A 12 ? SER A 20 ? SER A 44 SER A 52 1 ? 9 HELX_P HELX_P4 AA4 SER A 339 ? GLY A 352 ? SER A 393 GLY A 406 1 ? 14 HELX_P HELX_P5 AA5 PRO A 358 ? LEU A 362 ? PRO A 412 LEU A 416 5 ? 5 HELX_P HELX_P6 AA6 ASP A 373 ? HIS A 387 ? ASP A 427 HIS A 441 1 ? 15 HELX_P HELX_P7 AA7 ASP A 397 ? ALA A 401 ? ASP A 451 ALA A 455 5 ? 5 HELX_P HELX_P8 AA8 GLN A 416 ? LYS A 427 ? GLN A 470 LYS A 481 1 ? 12 HELX_P HELX_P9 AA9 TYR A 445 ? HIS A 454 ? TYR A 499 HIS A 508 1 ? 10 HELX_P HELX_P10 AB1 ASN A 482 ? PHE A 493 ? ASN A 536 PHE A 547 1 ? 12 HELX_P HELX_P11 AB2 GLY A 519 ? THR A 523 ? GLY A 573 THR A 577 5 ? 5 HELX_P HELX_P12 AB3 HIS A 530 ? TRP A 534 ? HIS A 584 TRP A 588 5 ? 5 HELX_P HELX_P13 AB4 GLU A 535 ? HIS A 540 ? GLU A 589 HIS A 594 1 ? 6 HELX_P HELX_P14 AB5 ILE A 542 ? ARG A 558 ? ILE A 596 ARG A 612 1 ? 17 HELX_P HELX_P15 AB6 GLY A 575 ? GLY A 580 ? GLY A 629 GLY A 634 5 ? 6 HELX_P HELX_P16 AB7 GLU A 590 ? VAL A 607 ? GLU A 644 VAL A 661 1 ? 18 HELX_P HELX_P17 AB8 GLU A 624 ? TYR A 637 ? GLU A 678 TYR A 691 1 ? 14 HELX_P HELX_P18 AB9 GLU A 653 ? LEU A 657 ? GLU A 707 LEU A 711 5 ? 5 HELX_P HELX_P19 AC1 ALA A 658 ? LEU A 675 ? ALA A 712 LEU A 729 1 ? 18 HELX_P HELX_P20 AC2 LEU A 675 ? GLY A 690 ? LEU A 729 GLY A 744 1 ? 16 HELX_P HELX_P21 AC3 PRO A 696 ? TYR A 701 ? PRO A 750 TYR A 755 1 ? 6 HELX_P HELX_P22 AC4 ASP A 704 ? PHE A 708 ? ASP A 758 PHE A 762 5 ? 5 HELX_P HELX_P23 AC5 SER A 787 ? LYS A 792 ? SER A 841 LYS A 846 1 ? 6 HELX_P HELX_P24 AC6 PHE A 820 ? ARG A 825 ? PHE A 874 ARG A 879 1 ? 6 HELX_P HELX_P25 AC7 PRO B 18 ? VAL B 22 ? PRO B 47 VAL B 51 5 ? 5 HELX_P HELX_P26 AC8 SER B 61 ? VAL B 63 ? SER B 90 VAL B 92 5 ? 3 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 9 SG ? ? ? 1_555 A CYS 15 SG ? ? A CYS 41 A CYS 47 1_555 ? ? ? ? ? ? ? 2.037 ? disulf2 disulf ? ? A CYS 601 SG ? ? ? 1_555 A CYS 612 SG ? ? A CYS 655 A CYS 666 1_555 ? ? ? ? ? ? ? 2.052 ? disulf3 disulf ? ? B CYS 10 SG ? ? ? 1_555 B CYS 29 SG ? ? B CYS 39 B CYS 58 1_555 ? ? ? ? ? ? ? 2.045 ? disulf4 disulf ? ? B CYS 27 SG ? ? ? 1_555 B CYS 41 SG ? ? B CYS 56 B CYS 70 1_555 ? ? ? ? ? ? ? 2.066 ? disulf5 disulf ? ? B CYS 48 SG ? ? ? 1_555 B CYS 70 SG ? ? B CYS 77 B CYS 99 1_555 ? ? ? ? ? ? ? 2.013 ? disulf6 disulf ? ? B CYS 68 SG ? ? ? 1_555 B CYS 83 SG ? ? B CYS 97 B CYS 112 1_555 ? ? ? ? ? ? ? 2.040 ? disulf7 disulf ? ? B CYS 71 SG ? ? ? 1_555 B CYS 87 SG ? ? B CYS 100 B CYS 116 1_555 ? ? ? ? ? ? ? 2.046 ? covale1 covale one ? A ASN 65 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 97 A NAG 1001 1_555 ? ? ? ? ? ? ? 1.435 ? metalc1 metalc ? ? B GLN 21 O ? ? ? 1_555 J CA . CA ? ? B GLN 50 B CA 201 1_555 ? ? ? ? ? ? ? 2.251 ? metalc2 metalc ? ? B ASP 24 OD1 ? ? ? 1_555 J CA . CA ? ? B ASP 53 B CA 201 1_555 ? ? ? ? ? ? ? 2.166 ? metalc3 metalc ? ? B TYR 26 O ? ? ? 1_555 J CA . CA ? ? B TYR 55 B CA 201 1_555 ? ? ? ? ? ? ? 2.293 ? metalc4 metalc ? ? B ASP 28 OD2 ? ? ? 1_555 J CA . CA ? ? B ASP 57 B CA 201 1_555 ? ? ? ? ? ? ? 2.378 ? metalc5 metalc ? ? B ASP 34 OD2 ? ? ? 1_555 J CA . CA ? ? B ASP 63 B CA 201 1_555 ? ? ? ? ? ? ? 2.209 ? metalc6 metalc ? ? B GLU 35 OE2 ? ? ? 1_555 J CA . CA ? ? B GLU 64 B CA 201 1_555 ? ? ? ? ? ? ? 2.350 ? metalc7 metalc ? ? B ARG 62 O ? ? ? 1_555 K CA . CA ? ? B ARG 91 B CA 202 1_555 ? ? ? ? ? ? ? 2.284 ? metalc8 metalc ? ? B ASP 65 OD1 ? ? ? 1_555 K CA . CA ? ? B ASP 94 B CA 202 1_555 ? ? ? ? ? ? ? 2.431 ? metalc9 metalc ? ? B VAL 67 O ? ? ? 1_555 K CA . CA ? ? B VAL 96 B CA 202 1_555 ? ? ? ? ? ? ? 2.286 ? metalc10 metalc ? ? B ASP 69 OD2 ? ? ? 1_555 K CA . CA ? ? B ASP 98 B CA 202 1_555 ? ? ? ? ? ? ? 2.327 ? metalc11 metalc ? ? B ASP 75 OD2 ? ? ? 1_555 K CA . CA ? ? B ASP 104 B CA 202 1_555 ? ? ? ? ? ? ? 2.268 ? metalc12 metalc ? ? B GLU 76 OE2 ? ? ? 1_555 K CA . CA ? ? B GLU 105 B CA 202 1_555 ? ? ? ? ? ? ? 2.172 ? covale2 covale both ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 1001 A NAG 1002 1_555 ? ? ? ? ? ? ? 1.438 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLY 113 A . ? GLY 145 A PRO 114 A ? PRO 146 A 1 6.51 2 GLN 122 A . ? GLN 154 A PRO 123 A ? PRO 155 A 1 -9.97 3 PRO 228 A . ? PRO 282 A GLU 229 A ? GLU 283 A 1 9.51 4 GLY 337 A . ? GLY 391 A PRO 338 A ? PRO 392 A 1 12.14 5 TRP 369 A . ? TRP 423 A ASN 370 A ? ASN 424 A 1 0.51 6 GLU 513 A . ? GLU 567 A PRO 514 A ? PRO 568 A 1 2.53 7 GLY 755 A . ? GLY 809 A PRO 756 A ? PRO 810 A 1 -7.99 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 4 ? AA2 ? 8 ? AA3 ? 7 ? AA4 ? 9 ? AA5 ? 2 ? AA6 ? 8 ? AA7 ? 3 ? AA8 ? 6 ? AA9 ? 2 ? AB1 ? 5 ? AB2 ? 6 ? AB3 ? 2 ? AB4 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? anti-parallel AA1 3 4 ? anti-parallel AA2 1 2 ? anti-parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA2 4 5 ? anti-parallel AA2 5 6 ? anti-parallel AA2 6 7 ? anti-parallel AA2 7 8 ? anti-parallel AA3 1 2 ? anti-parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA3 4 5 ? anti-parallel AA3 5 6 ? anti-parallel AA3 6 7 ? anti-parallel AA4 1 2 ? anti-parallel AA4 2 3 ? anti-parallel AA4 3 4 ? anti-parallel AA4 4 5 ? anti-parallel AA4 5 6 ? anti-parallel AA4 6 7 ? anti-parallel AA4 7 8 ? anti-parallel AA4 8 9 ? anti-parallel AA5 1 2 ? anti-parallel AA6 1 2 ? parallel AA6 2 3 ? parallel AA6 3 4 ? parallel AA6 4 5 ? parallel AA6 5 6 ? parallel AA6 6 7 ? parallel AA6 7 8 ? parallel AA7 1 2 ? anti-parallel AA7 2 3 ? anti-parallel AA8 1 2 ? anti-parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA8 4 5 ? anti-parallel AA8 5 6 ? anti-parallel AA9 1 2 ? anti-parallel AB1 1 2 ? anti-parallel AB1 2 3 ? parallel AB1 3 4 ? anti-parallel AB1 4 5 ? anti-parallel AB2 1 2 ? anti-parallel AB2 2 3 ? anti-parallel AB2 3 4 ? anti-parallel AB2 4 5 ? anti-parallel AB2 5 6 ? anti-parallel AB3 1 2 ? anti-parallel AB4 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 TYR A 28 ? LEU A 37 ? TYR A 60 LEU A 69 AA1 2 LEU A 42 ? HIS A 48 ? LEU A 74 HIS A 80 AA1 3 LEU A 54 ? LEU A 62 ? LEU A 86 LEU A 94 AA1 4 THR A 93 ? ALA A 94 ? THR A 125 ALA A 126 AA2 1 TYR A 28 ? LEU A 37 ? TYR A 60 LEU A 69 AA2 2 LEU A 42 ? HIS A 48 ? LEU A 74 HIS A 80 AA2 3 LEU A 54 ? LEU A 62 ? LEU A 86 LEU A 94 AA2 4 MET A 66 ? GLU A 73 ? MET A 98 GLU A 105 AA2 5 ILE A 330 ? MET A 335 ? ILE A 384 MET A 389 AA2 6 ASP A 278 ? TRP A 283 ? ASP A 332 TRP A 337 AA2 7 VAL A 269 ? HIS A 273 ? VAL A 323 HIS A 327 AA2 8 HIS A 223 ? GLY A 226 ? HIS A 277 GLY A 280 AA3 1 LEU A 96 ? ARG A 101 ? LEU A 128 ARG A 133 AA3 2 SER A 105 ? VAL A 110 ? SER A 137 VAL A 142 AA3 3 TYR A 115 ? THR A 120 ? TYR A 147 THR A 152 AA3 4 ARG A 125 ? GLU A 130 ? ARG A 157 GLU A 162 AA3 5 SER A 133 ? VAL A 138 ? SER A 165 VAL A 170 AA3 6 VAL A 212 ? PRO A 219 ? VAL A 266 PRO A 273 AA3 7 ALA A 145 ? PHE A 146 ? ALA A 177 PHE A 178 AA4 1 LEU A 96 ? ARG A 101 ? LEU A 128 ARG A 133 AA4 2 SER A 105 ? VAL A 110 ? SER A 137 VAL A 142 AA4 3 TYR A 115 ? THR A 120 ? TYR A 147 THR A 152 AA4 4 ARG A 125 ? GLU A 130 ? ARG A 157 GLU A 162 AA4 5 SER A 133 ? VAL A 138 ? SER A 165 VAL A 170 AA4 6 VAL A 212 ? PRO A 219 ? VAL A 266 PRO A 273 AA4 7 GLN A 318 ? SER A 325 ? GLN A 372 SER A 379 AA4 8 THR A 289 ? ASN A 296 ? THR A 343 ASN A 350 AA4 9 TYR A 245 ? LEU A 247 ? TYR A 299 LEU A 301 AA5 1 GLU A 196 ? PHE A 198 ? GLU A 250 PHE A 252 AA5 2 HIS A 201 ? ASP A 203 ? HIS A 255 ASP A 257 AA6 1 CYS A 612 ? GLY A 613 ? CYS A 666 GLY A 667 AA6 2 ALA A 581 ? TRP A 583 ? ALA A 635 TRP A 637 AA6 3 VAL A 567 ? SER A 569 ? VAL A 621 SER A 623 AA6 4 LEU A 505 ? ASN A 509 ? LEU A 559 ASN A 563 AA6 5 LYS A 430 ? ILE A 434 ? LYS A 484 ILE A 488 AA6 6 VAL A 393 ? LEU A 396 ? VAL A 447 LEU A 450 AA6 7 TYR A 364 ? GLN A 366 ? TYR A 418 GLN A 420 AA6 8 PHE A 641 ? ALA A 643 ? PHE A 695 ALA A 697 AA7 1 ILE A 439 ? LYS A 440 ? ILE A 493 LYS A 494 AA7 2 GLY A 473 ? SER A 476 ? GLY A 527 SER A 530 AA7 3 GLY A 468 ? CYS A 470 ? GLY A 522 CYS A 524 AA8 1 MET A 694 ? ARG A 695 ? MET A 748 ARG A 749 AA8 2 PHE A 714 ? LEU A 716 ? PHE A 768 LEU A 770 AA8 3 LEU A 720 ? ILE A 722 ? LEU A 774 ILE A 776 AA8 4 VAL A 770 ? ARG A 773 ? VAL A 824 ARG A 827 AA8 5 VAL A 743 ? ASP A 746 ? VAL A 797 ASP A 800 AA8 6 LYS A 752 ? HIS A 754 ? LYS A 806 HIS A 808 AA9 1 GLY A 732 ? LEU A 737 ? GLY A 786 LEU A 791 AA9 2 GLN A 757 ? PRO A 762 ? GLN A 811 PRO A 816 AB1 1 THR A 776 ? ARG A 780 ? THR A 830 ARG A 834 AB1 2 ILE A 796 ? ALA A 801 ? ILE A 850 ALA A 855 AB1 3 TRP A 856 ? MET A 863 ? TRP A 910 MET A 917 AB1 4 VAL A 893 ? SER A 902 ? VAL A 947 SER A 956 AB1 5 PHE A 885 ? ASP A 888 ? PHE A 939 ASP A 942 AB2 1 ALA A 808 ? LEU A 814 ? ALA A 862 LEU A 868 AB2 2 LEU A 829 ? SER A 836 ? LEU A 883 SER A 890 AB2 3 THR A 839 ? SER A 844 ? THR A 893 SER A 898 AB2 4 TRP A 907 ? ARG A 912 ? TRP A 961 ARG A 966 AB2 5 ALA A 870 ? GLN A 874 ? ALA A 924 GLN A 928 AB2 6 SER A 881 ? ARG A 882 ? SER A 935 ARG A 936 AB3 1 PHE B 8 ? THR B 9 ? PHE B 37 THR B 38 AB3 2 THR B 16 ? ILE B 17 ? THR B 45 ILE B 46 AB4 1 SER B 45 ? CYS B 48 ? SER B 74 CYS B 77 AB4 2 LEU B 56 ? LEU B 59 ? LEU B 85 LEU B 88 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N GLN A 36 ? N GLN A 68 O THR A 43 ? O THR A 75 AA1 2 3 N VAL A 44 ? N VAL A 76 O LEU A 57 ? O LEU A 89 AA1 3 4 N GLY A 61 ? N GLY A 93 O ALA A 94 ? O ALA A 126 AA2 1 2 N GLN A 36 ? N GLN A 68 O THR A 43 ? O THR A 75 AA2 2 3 N VAL A 44 ? N VAL A 76 O LEU A 57 ? O LEU A 89 AA2 3 4 N GLU A 58 ? N GLU A 90 O ARG A 70 ? O ARG A 102 AA2 4 5 N THR A 67 ? N THR A 99 O LEU A 334 ? O LEU A 388 AA2 5 6 O MET A 335 ? O MET A 389 N GLY A 280 ? N GLY A 334 AA2 6 7 O LEU A 279 ? O LEU A 333 N ALA A 272 ? N ALA A 326 AA2 7 8 O LEU A 271 ? O LEU A 325 N TYR A 225 ? N TYR A 279 AA3 1 2 N GLY A 100 ? N GLY A 132 O GLU A 107 ? O GLU A 139 AA3 2 3 N LEU A 108 ? N LEU A 140 O ILE A 117 ? O ILE A 149 AA3 3 4 N LYS A 116 ? N LYS A 148 O LEU A 129 ? O LEU A 161 AA3 4 5 N LEU A 128 ? N LEU A 160 O LEU A 136 ? O LEU A 168 AA3 5 6 N SER A 137 ? N SER A 169 O SER A 217 ? O SER A 271 AA3 6 7 O GLY A 213 ? O GLY A 267 N ALA A 145 ? N ALA A 177 AA4 1 2 N GLY A 100 ? N GLY A 132 O GLU A 107 ? O GLU A 139 AA4 2 3 N LEU A 108 ? N LEU A 140 O ILE A 117 ? O ILE A 149 AA4 3 4 N LYS A 116 ? N LYS A 148 O LEU A 129 ? O LEU A 161 AA4 4 5 N LEU A 128 ? N LEU A 160 O LEU A 136 ? O LEU A 168 AA4 5 6 N SER A 137 ? N SER A 169 O SER A 217 ? O SER A 271 AA4 6 7 N VAL A 212 ? N VAL A 266 O SER A 325 ? O SER A 379 AA4 7 8 O ASP A 320 ? O ASP A 374 N SER A 294 ? N SER A 348 AA4 8 9 O THR A 289 ? O THR A 343 N LEU A 247 ? N LEU A 301 AA5 1 2 N GLU A 196 ? N GLU A 250 O ASP A 203 ? O ASP A 257 AA6 1 2 O GLY A 613 ? O GLY A 667 N VAL A 582 ? N VAL A 636 AA6 2 3 O ALA A 581 ? O ALA A 635 N VAL A 567 ? N VAL A 621 AA6 3 4 O LEU A 568 ? O LEU A 622 N ASN A 509 ? N ASN A 563 AA6 4 5 O TYR A 506 ? O TYR A 560 N LEU A 431 ? N LEU A 485 AA6 5 6 O VAL A 432 ? O VAL A 486 N LEU A 396 ? N LEU A 450 AA6 6 7 O VAL A 393 ? O VAL A 447 N GLN A 366 ? N GLN A 420 AA6 7 8 N HIS A 365 ? N HIS A 419 O PHE A 641 ? O PHE A 695 AA7 1 2 N ILE A 439 ? N ILE A 493 O SER A 476 ? O SER A 530 AA7 2 3 O GLY A 473 ? O GLY A 527 N CYS A 470 ? N CYS A 524 AA8 1 2 N ARG A 695 ? N ARG A 749 O MET A 715 ? O MET A 769 AA8 2 3 N PHE A 714 ? N PHE A 768 O ILE A 722 ? O ILE A 776 AA8 3 4 N LEU A 721 ? N LEU A 775 O PHE A 771 ? O PHE A 825 AA8 4 5 O GLN A 772 ? O GLN A 826 N TYR A 745 ? N TYR A 799 AA8 5 6 N TRP A 744 ? N TRP A 798 O HIS A 753 ? O HIS A 807 AA9 1 2 N VAL A 735 ? N VAL A 789 O LEU A 759 ? O LEU A 813 AB1 1 2 N THR A 776 ? N THR A 830 O ALA A 801 ? O ALA A 855 AB1 2 3 N VAL A 800 ? N VAL A 854 O MET A 863 ? O MET A 917 AB1 3 4 N ILE A 862 ? N ILE A 916 O LEU A 894 ? O LEU A 948 AB1 4 5 O ILE A 895 ? O ILE A 949 N GLN A 886 ? N GLN A 940 AB2 1 2 N ALA A 808 ? N ALA A 862 O PHE A 835 ? O PHE A 889 AB2 2 3 N ARG A 832 ? N ARG A 886 O SER A 843 ? O SER A 897 AB2 3 4 N LEU A 840 ? N LEU A 894 O ILE A 909 ? O ILE A 963 AB2 4 5 O ARG A 912 ? O ARG A 966 N ALA A 870 ? N ALA A 924 AB2 5 6 N LEU A 873 ? N LEU A 927 O SER A 881 ? O SER A 935 AB3 1 2 N PHE B 8 ? N PHE B 37 O ILE B 17 ? O ILE B 46 AB4 1 2 N CYS B 48 ? N CYS B 77 O LEU B 56 ? O LEU B 85 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A FMT 1003 ? 2 'binding site for residue FMT A 1003' AC2 Software A ACT 1004 ? 6 'binding site for residue ACT A 1004' AC3 Software A NBV 1005 ? 14 'binding site for residue NBV A 1005' AC4 Software A P6G 1006 ? 6 'binding site for residue P6G A 1006' AC5 Software A P6G 1007 ? 5 'binding site for residue P6G A 1007' AC6 Software B CA 201 ? 6 'binding site for residue CA B 201' AC7 Software B CA 202 ? 6 'binding site for residue CA B 202' AC8 Software A ASN 97 ? 10 'binding site for Poly-Saccharide residues NAG A 1001 through NAG A 1002 bound to ASN A 97' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 2 ILE A 747 ? ILE A 801 . ? 1_555 ? 2 AC1 2 PHE A 799 ? PHE A 853 . ? 1_555 ? 3 AC2 6 VAL A 56 ? VAL A 88 . ? 1_555 ? 4 AC2 6 GLU A 58 ? GLU A 90 . ? 1_555 ? 5 AC2 6 ARG A 70 ? ARG A 102 . ? 1_555 ? 6 AC2 6 ILE A 71 ? ILE A 103 . ? 1_555 ? 7 AC2 6 ASP A 72 ? ASP A 104 . ? 1_555 ? 8 AC2 6 ARG A 82 ? ARG A 114 . ? 1_555 ? 9 AC3 14 TRP A 369 ? TRP A 423 . ? 1_555 ? 10 AC3 14 ASP A 397 ? ASP A 451 . ? 1_555 ? 11 AC3 14 ILE A 398 ? ILE A 452 . ? 1_555 ? 12 AC3 14 TRP A 508 ? TRP A 562 . ? 1_555 ? 13 AC3 14 ASP A 510 ? ASP A 564 . ? 1_555 ? 14 AC3 14 MET A 511 ? MET A 565 . ? 1_555 ? 15 AC3 14 PHE A 517 ? PHE A 571 . ? 1_555 ? 16 AC3 14 ARG A 570 ? ARG A 624 . ? 1_555 ? 17 AC3 14 TRP A 583 ? TRP A 637 . ? 1_555 ? 18 AC3 14 ASP A 586 ? ASP A 640 . ? 1_555 ? 19 AC3 14 PHE A 619 ? PHE A 673 . ? 1_555 ? 20 AC3 14 HIS A 644 ? HIS A 698 . ? 1_555 ? 21 AC3 14 HOH L . ? HOH A 1105 . ? 1_555 ? 22 AC3 14 HOH L . ? HOH A 1142 . ? 1_555 ? 23 AC4 6 ARG A 80 ? ARG A 112 . ? 1_555 ? 24 AC4 6 TYR A 81 ? TYR A 113 . ? 1_555 ? 25 AC4 6 ARG A 82 ? ARG A 114 . ? 1_555 ? 26 AC4 6 GLY A 532 ? GLY A 586 . ? 1_555 ? 27 AC4 6 TRP A 534 ? TRP A 588 . ? 1_555 ? 28 AC4 6 TYR A 760 ? TYR A 814 . ? 1_556 ? 29 AC5 5 SER A 706 ? SER A 760 . ? 1_555 ? 30 AC5 5 GLU A 711 ? GLU A 765 . ? 1_555 ? 31 AC5 5 ASP A 712 ? ASP A 766 . ? 1_555 ? 32 AC5 5 HOH L . ? HOH A 1102 . ? 1_555 ? 33 AC5 5 HOH L . ? HOH A 1279 . ? 1_555 ? 34 AC6 6 GLN B 21 ? GLN B 50 . ? 1_555 ? 35 AC6 6 ASP B 24 ? ASP B 53 . ? 1_555 ? 36 AC6 6 TYR B 26 ? TYR B 55 . ? 1_555 ? 37 AC6 6 ASP B 28 ? ASP B 57 . ? 1_555 ? 38 AC6 6 ASP B 34 ? ASP B 63 . ? 1_555 ? 39 AC6 6 GLU B 35 ? GLU B 64 . ? 1_555 ? 40 AC7 6 ARG B 62 ? ARG B 91 . ? 1_555 ? 41 AC7 6 ASP B 65 ? ASP B 94 . ? 1_555 ? 42 AC7 6 VAL B 67 ? VAL B 96 . ? 1_555 ? 43 AC7 6 ASP B 69 ? ASP B 98 . ? 1_555 ? 44 AC7 6 ASP B 75 ? ASP B 104 . ? 1_555 ? 45 AC7 6 GLU B 76 ? GLU B 105 . ? 1_555 ? 46 AC8 10 ASN A 65 ? ASN A 97 . ? 1_555 ? 47 AC8 10 TYR A 115 ? TYR A 147 . ? 1_555 ? 48 AC8 10 GLU A 130 ? GLU A 162 . ? 1_555 ? 49 AC8 10 GLY A 337 ? GLY A 391 . ? 1_555 ? 50 AC8 10 PRO A 338 ? PRO A 392 . ? 1_555 ? 51 AC8 10 ASP A 342 ? ASP A 396 . ? 1_555 ? 52 AC8 10 GLN A 346 ? GLN A 400 . ? 1_555 ? 53 AC8 10 HOH L . ? HOH A 1159 . ? 1_555 ? 54 AC8 10 HOH L . ? HOH A 1185 . ? 1_555 ? 55 AC8 10 HOH L . ? HOH A 1285 . ? 1_555 ? # _atom_sites.entry_id 5IEF _atom_sites.fract_transf_matrix[1][1] 0.009630 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.005784 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.015931 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CA H N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . VAL A 1 1 ? 98.937 543.083 63.849 1.00 39.43 ? 33 VAL A N 1 ATOM 2 C CA . VAL A 1 1 ? 98.790 543.624 65.194 1.00 38.62 ? 33 VAL A CA 1 ATOM 3 C C . VAL A 1 1 ? 97.398 544.077 65.531 1.00 42.99 ? 33 VAL A C 1 ATOM 4 O O . VAL A 1 1 ? 96.701 544.681 64.704 1.00 42.02 ? 33 VAL A O 1 ATOM 5 C CB . VAL A 1 1 ? 99.683 544.863 65.522 1.00 41.35 ? 33 VAL A CB 1 ATOM 6 C CG1 . VAL A 1 1 ? 100.374 544.729 66.863 1.00 40.73 ? 33 VAL A CG1 1 ATOM 7 C CG2 . VAL A 1 1 ? 100.648 545.216 64.426 1.00 41.25 ? 33 VAL A CG2 1 ATOM 8 N N . ASP A 1 2 ? 97.103 543.965 66.832 1.00 40.03 ? 34 ASP A N 1 ATOM 9 C CA . ASP A 1 2 ? 95.965 544.585 67.476 1.00 39.07 ? 34 ASP A CA 1 ATOM 10 C C . ASP A 1 2 ? 96.565 545.772 68.274 1.00 41.80 ? 34 ASP A C 1 ATOM 11 O O . ASP A 1 2 ? 97.010 545.615 69.422 1.00 42.03 ? 34 ASP A O 1 ATOM 12 C CB . ASP A 1 2 ? 95.213 543.609 68.386 1.00 40.15 ? 34 ASP A CB 1 ATOM 13 C CG . ASP A 1 2 ? 94.032 544.234 69.120 1.00 47.34 ? 34 ASP A CG 1 ATOM 14 O OD1 . ASP A 1 2 ? 93.853 545.481 69.037 1.00 44.78 ? 34 ASP A OD1 1 ATOM 15 O OD2 . ASP A 1 2 ? 93.305 543.490 69.797 1.00 57.86 ? 34 ASP A OD2 1 ATOM 16 N N . ARG A 1 3 ? 96.555 546.956 67.659 1.00 36.65 ? 35 ARG A N 1 ATOM 17 C CA . ARG A 1 3 ? 97.111 548.159 68.260 1.00 35.88 ? 35 ARG A CA 1 ATOM 18 C C . ARG A 1 3 ? 96.430 548.549 69.540 1.00 40.65 ? 35 ARG A C 1 ATOM 19 O O . ARG A 1 3 ? 97.060 549.195 70.365 1.00 40.86 ? 35 ARG A O 1 ATOM 20 C CB . ARG A 1 3 ? 97.074 549.318 67.287 1.00 35.88 ? 35 ARG A CB 1 ATOM 21 C CG . ARG A 1 3 ? 98.010 549.119 66.111 1.00 50.74 ? 35 ARG A CG 1 ATOM 22 C CD . ARG A 1 3 ? 97.791 550.150 65.023 1.00 65.73 ? 35 ARG A CD 1 ATOM 23 N NE . ARG A 1 3 ? 98.636 549.893 63.857 1.00 74.31 ? 35 ARG A NE 1 ATOM 24 C CZ . ARG A 1 3 ? 99.727 550.587 63.532 1.00 89.87 ? 35 ARG A CZ 1 ATOM 25 N NH1 . ARG A 1 3 ? 100.130 551.603 64.289 1.00 77.11 ? 35 ARG A NH1 1 ATOM 26 N NH2 . ARG A 1 3 ? 100.424 550.269 62.452 1.00 79.55 ? 35 ARG A NH2 1 ATOM 27 N N . SER A 1 4 ? 95.167 548.134 69.736 1.00 37.88 ? 36 SER A N 1 ATOM 28 C CA . SER A 1 4 ? 94.403 548.480 70.932 1.00 36.58 ? 36 SER A CA 1 ATOM 29 C C . SER A 1 4 ? 94.922 547.787 72.173 1.00 38.21 ? 36 SER A C 1 ATOM 30 O O . SER A 1 4 ? 94.531 548.178 73.271 1.00 38.88 ? 36 SER A O 1 ATOM 31 C CB . SER A 1 4 ? 92.906 548.253 70.737 1.00 39.04 ? 36 SER A CB 1 ATOM 32 O OG . SER A 1 4 ? 92.548 546.894 70.923 1.00 47.92 ? 36 SER A OG 1 ATOM 33 N N . ASN A 1 5 ? 95.809 546.788 72.019 1.00 32.02 ? 37 ASN A N 1 ATOM 34 C CA . ASN A 1 5 ? 96.436 546.120 73.159 1.00 30.54 ? 37 ASN A CA 1 ATOM 35 C C . ASN A 1 5 ? 97.632 546.887 73.699 1.00 32.32 ? 37 ASN A C 1 ATOM 36 O O . ASN A 1 5 ? 98.150 546.531 74.755 1.00 31.49 ? 37 ASN A O 1 ATOM 37 C CB . ASN A 1 5 ? 96.886 544.722 72.785 1.00 28.35 ? 37 ASN A CB 1 ATOM 38 C CG . ASN A 1 5 ? 95.753 543.761 72.733 1.00 57.44 ? 37 ASN A CG 1 ATOM 39 O OD1 . ASN A 1 5 ? 94.713 543.947 73.376 1.00 62.54 ? 37 ASN A OD1 1 ATOM 40 N ND2 . ASN A 1 5 ? 95.919 542.711 71.956 1.00 47.72 ? 37 ASN A ND2 1 ATOM 41 N N . PHE A 1 6 ? 98.076 547.925 72.976 1.00 26.80 ? 38 PHE A N 1 ATOM 42 C CA . PHE A 1 6 ? 99.293 548.664 73.275 1.00 25.04 ? 38 PHE A CA 1 ATOM 43 C C . PHE A 1 6 ? 99.022 550.135 73.392 1.00 30.35 ? 38 PHE A C 1 ATOM 44 O O . PHE A 1 6 ? 98.355 550.698 72.545 1.00 31.31 ? 38 PHE A O 1 ATOM 45 C CB . PHE A 1 6 ? 100.336 548.348 72.189 1.00 25.13 ? 38 PHE A CB 1 ATOM 46 C CG . PHE A 1 6 ? 100.612 546.859 72.103 1.00 25.04 ? 38 PHE A CG 1 ATOM 47 C CD1 . PHE A 1 6 ? 101.424 546.235 73.040 1.00 25.57 ? 38 PHE A CD1 1 ATOM 48 C CD2 . PHE A 1 6 ? 99.990 546.069 71.137 1.00 25.75 ? 38 PHE A CD2 1 ATOM 49 C CE1 . PHE A 1 6 ? 101.623 544.861 73.010 1.00 25.05 ? 38 PHE A CE1 1 ATOM 50 C CE2 . PHE A 1 6 ? 100.217 544.686 71.090 1.00 26.81 ? 38 PHE A CE2 1 ATOM 51 C CZ . PHE A 1 6 ? 101.025 544.092 72.032 1.00 23.86 ? 38 PHE A CZ 1 ATOM 52 N N . LYS A 1 7 ? 99.531 550.761 74.439 1.00 26.35 ? 39 LYS A N 1 ATOM 53 C CA . LYS A 1 7 ? 99.307 552.184 74.689 1.00 24.84 ? 39 LYS A CA 1 ATOM 54 C C . LYS A 1 7 ? 99.933 553.101 73.652 1.00 31.18 ? 39 LYS A C 1 ATOM 55 O O . LYS A 1 7 ? 101.111 552.966 73.302 1.00 29.74 ? 39 LYS A O 1 ATOM 56 C CB . LYS A 1 7 ? 99.860 552.595 76.066 1.00 24.32 ? 39 LYS A CB 1 ATOM 57 C CG . LYS A 1 7 ? 99.225 551.922 77.264 1.00 21.57 ? 39 LYS A CG 1 ATOM 58 C CD . LYS A 1 7 ? 99.885 552.383 78.542 1.00 26.29 ? 39 LYS A CD 1 ATOM 59 C CE . LYS A 1 7 ? 99.703 551.353 79.627 1.00 37.25 ? 39 LYS A CE 1 ATOM 60 N NZ . LYS A 1 7 ? 100.413 551.750 80.860 1.00 45.18 ? 39 LYS A NZ 1 ATOM 61 N N . THR A 1 8 ? 99.151 554.104 73.224 1.00 30.34 ? 40 THR A N 1 ATOM 62 C CA . THR A 1 8 ? 99.638 555.218 72.413 1.00 29.80 ? 40 THR A CA 1 ATOM 63 C C . THR A 1 8 ? 100.098 556.183 73.496 1.00 31.19 ? 40 THR A C 1 ATOM 64 O O . THR A 1 8 ? 99.799 555.952 74.662 1.00 28.71 ? 40 THR A O 1 ATOM 65 C CB . THR A 1 8 ? 98.519 555.842 71.565 1.00 34.97 ? 40 THR A CB 1 ATOM 66 O OG1 . THR A 1 8 ? 97.412 556.163 72.413 1.00 42.12 ? 40 THR A OG1 1 ATOM 67 C CG2 . THR A 1 8 ? 98.064 554.926 70.455 1.00 27.20 ? 40 THR A CG2 1 ATOM 68 N N . CYS A 1 9 ? 100.822 557.237 73.131 1.00 29.71 ? 41 CYS A N 1 ATOM 69 C CA . CYS A 1 9 ? 101.310 558.243 74.076 1.00 30.93 ? 41 CYS A CA 1 ATOM 70 C C . CYS A 1 9 ? 100.162 558.822 74.918 1.00 38.35 ? 41 CYS A C 1 ATOM 71 O O . CYS A 1 9 ? 100.293 559.007 76.123 1.00 38.46 ? 41 CYS A O 1 ATOM 72 C CB . CYS A 1 9 ? 102.043 559.341 73.324 1.00 31.38 ? 41 CYS A CB 1 ATOM 73 S SG . CYS A 1 9 ? 102.665 560.658 74.387 1.00 35.79 ? 41 CYS A SG 1 ATOM 74 N N . ASP A 1 10 ? 99.014 559.044 74.274 1.00 37.46 ? 42 ASP A N 1 ATOM 75 C CA . ASP A 1 10 ? 97.824 559.575 74.914 1.00 37.72 ? 42 ASP A CA 1 ATOM 76 C C . ASP A 1 10 ? 97.275 558.651 75.987 1.00 39.78 ? 42 ASP A C 1 ATOM 77 O O . ASP A 1 10 ? 96.672 559.134 76.936 1.00 41.54 ? 42 ASP A O 1 ATOM 78 C CB . ASP A 1 10 ? 96.751 559.873 73.867 1.00 40.74 ? 42 ASP A CB 1 ATOM 79 C CG . ASP A 1 10 ? 96.016 561.143 74.182 1.00 61.15 ? 42 ASP A CG 1 ATOM 80 O OD1 . ASP A 1 10 ? 96.643 562.228 74.098 1.00 63.51 ? 42 ASP A OD1 1 ATOM 81 O OD2 . ASP A 1 10 ? 94.842 561.055 74.606 1.00 70.36 ? 42 ASP A OD2 1 ATOM 82 N N . GLU A 1 11 ? 97.518 557.338 75.867 1.00 32.99 ? 43 GLU A N 1 ATOM 83 C CA . GLU A 1 11 ? 97.057 556.320 76.811 1.00 31.12 ? 43 GLU A CA 1 ATOM 84 C C . GLU A 1 11 ? 98.041 556.031 77.942 1.00 36.40 ? 43 GLU A C 1 ATOM 85 O O . GLU A 1 11 ? 97.737 555.252 78.867 1.00 36.73 ? 43 GLU A O 1 ATOM 86 C CB . GLU A 1 11 ? 96.697 555.043 76.060 1.00 31.50 ? 43 GLU A CB 1 ATOM 87 C CG . GLU A 1 11 ? 95.542 555.251 75.096 1.00 33.30 ? 43 GLU A CG 1 ATOM 88 C CD . GLU A 1 11 ? 95.323 554.114 74.122 1.00 49.84 ? 43 GLU A CD 1 ATOM 89 O OE1 . GLU A 1 11 ? 94.238 553.494 74.173 1.00 48.83 ? 43 GLU A OE1 1 ATOM 90 O OE2 . GLU A 1 11 ? 96.232 553.841 73.304 1.00 41.24 ? 43 GLU A OE2 1 ATOM 91 N N . SER A 1 12 ? 99.232 556.639 77.846 1.00 31.34 ? 44 SER A N 1 ATOM 92 C CA . SER A 1 12 ? 100.258 556.535 78.855 1.00 30.66 ? 44 SER A CA 1 ATOM 93 C C . SER A 1 12 ? 100.241 557.909 79.546 1.00 35.01 ? 44 SER A C 1 ATOM 94 O O . SER A 1 12 ? 100.731 558.888 78.975 1.00 35.02 ? 44 SER A O 1 ATOM 95 C CB . SER A 1 12 ? 101.598 556.232 78.209 1.00 33.03 ? 44 SER A CB 1 ATOM 96 O OG . SER A 1 12 ? 102.618 556.462 79.164 1.00 40.89 ? 44 SER A OG 1 ATOM 97 N N . SER A 1 13 ? 99.611 558.002 80.738 1.00 29.59 ? 45 SER A N 1 ATOM 98 C CA . SER A 1 13 ? 99.404 559.307 81.368 1.00 28.71 ? 45 SER A CA 1 ATOM 99 C C . SER A 1 13 ? 100.684 560.153 81.493 1.00 32.04 ? 45 SER A C 1 ATOM 100 O O . SER A 1 13 ? 100.612 561.341 81.198 1.00 31.52 ? 45 SER A O 1 ATOM 101 C CB . SER A 1 13 ? 98.661 559.203 82.697 1.00 29.85 ? 45 SER A CB 1 ATOM 102 O OG . SER A 1 13 ? 99.483 558.815 83.777 1.00 36.57 ? 45 SER A OG 1 ATOM 103 N N . PHE A 1 14 ? 101.846 559.554 81.842 1.00 28.00 ? 46 PHE A N 1 ATOM 104 C CA . PHE A 1 14 ? 103.103 560.320 81.920 1.00 27.31 ? 46 PHE A CA 1 ATOM 105 C C . PHE A 1 14 ? 103.564 560.824 80.547 1.00 34.36 ? 46 PHE A C 1 ATOM 106 O O . PHE A 1 14 ? 104.114 561.923 80.468 1.00 33.94 ? 46 PHE A O 1 ATOM 107 C CB . PHE A 1 14 ? 104.232 559.566 82.660 1.00 27.66 ? 46 PHE A CB 1 ATOM 108 C CG . PHE A 1 14 ? 105.047 558.630 81.793 1.00 28.00 ? 46 PHE A CG 1 ATOM 109 C CD1 . PHE A 1 14 ? 106.184 559.087 81.118 1.00 28.25 ? 46 PHE A CD1 1 ATOM 110 C CD2 . PHE A 1 14 ? 104.679 557.294 81.645 1.00 28.20 ? 46 PHE A CD2 1 ATOM 111 C CE1 . PHE A 1 14 ? 106.932 558.229 80.315 1.00 27.53 ? 46 PHE A CE1 1 ATOM 112 C CE2 . PHE A 1 14 ? 105.436 556.433 80.844 1.00 29.71 ? 46 PHE A CE2 1 ATOM 113 C CZ . PHE A 1 14 ? 106.558 556.909 80.184 1.00 26.89 ? 46 PHE A CZ 1 ATOM 114 N N . CYS A 1 15 ? 103.337 560.043 79.464 1.00 32.49 ? 47 CYS A N 1 ATOM 115 C CA . CYS A 1 15 ? 103.700 560.531 78.128 1.00 31.59 ? 47 CYS A CA 1 ATOM 116 C C . CYS A 1 15 ? 102.814 561.741 77.770 1.00 33.84 ? 47 CYS A C 1 ATOM 117 O O . CYS A 1 15 ? 103.300 562.722 77.213 1.00 32.92 ? 47 CYS A O 1 ATOM 118 C CB . CYS A 1 15 ? 103.567 559.428 77.088 1.00 31.73 ? 47 CYS A CB 1 ATOM 119 S SG . CYS A 1 15 ? 104.214 559.871 75.451 1.00 36.00 ? 47 CYS A SG 1 ATOM 120 N N . LYS A 1 16 ? 101.506 561.647 78.074 1.00 28.66 ? 48 LYS A N 1 ATOM 121 C CA . LYS A 1 16 ? 100.554 562.711 77.789 1.00 27.01 ? 48 LYS A CA 1 ATOM 122 C C . LYS A 1 16 ? 100.939 563.981 78.531 1.00 32.79 ? 48 LYS A C 1 ATOM 123 O O . LYS A 1 16 ? 100.970 565.040 77.908 1.00 34.11 ? 48 LYS A O 1 ATOM 124 C CB . LYS A 1 16 ? 99.126 562.279 78.114 1.00 27.54 ? 48 LYS A CB 1 ATOM 125 C CG . LYS A 1 16 ? 98.096 563.268 77.594 1.00 31.76 ? 48 LYS A CG 1 ATOM 126 C CD . LYS A 1 16 ? 96.703 562.901 77.993 1.00 41.84 ? 48 LYS A CD 1 ATOM 127 C CE . LYS A 1 16 ? 95.692 563.800 77.318 1.00 55.72 ? 48 LYS A CE 1 ATOM 128 N NZ . LYS A 1 16 ? 94.373 563.128 77.179 1.00 65.35 ? 48 LYS A NZ 1 ATOM 129 N N . ARG A 1 17 ? 101.311 563.871 79.834 1.00 28.24 ? 49 ARG A N 1 ATOM 130 C CA . ARG A 1 17 ? 101.748 565.011 80.658 1.00 27.23 ? 49 ARG A CA 1 ATOM 131 C C . ARG A 1 17 ? 102.982 565.646 80.096 1.00 32.83 ? 49 ARG A C 1 ATOM 132 O O . ARG A 1 17 ? 103.006 566.860 79.851 1.00 32.77 ? 49 ARG A O 1 ATOM 133 C CB . ARG A 1 17 ? 101.986 564.616 82.127 1.00 22.08 ? 49 ARG A CB 1 ATOM 134 C CG . ARG A 1 17 ? 100.698 564.264 82.863 1.00 21.96 ? 49 ARG A CG 1 ATOM 135 C CD . ARG A 1 17 ? 100.862 564.190 84.370 1.00 29.81 ? 49 ARG A CD 1 ATOM 136 N NE . ARG A 1 17 ? 101.942 563.295 84.795 1.00 38.20 ? 49 ARG A NE 1 ATOM 137 C CZ . ARG A 1 17 ? 101.813 561.985 84.960 1.00 39.98 ? 49 ARG A CZ 1 ATOM 138 N NH1 . ARG A 1 17 ? 100.650 561.391 84.724 1.00 21.78 ? 49 ARG A NH1 1 ATOM 139 N NH2 . ARG A 1 17 ? 102.852 561.257 85.344 1.00 23.10 ? 49 ARG A NH2 1 ATOM 140 N N . GLN A 1 18 ? 104.002 564.820 79.826 1.00 30.18 ? 50 GLN A N 1 ATOM 141 C CA . GLN A 1 18 ? 105.264 565.319 79.276 1.00 29.19 ? 50 GLN A CA 1 ATOM 142 C C . GLN A 1 18 ? 105.073 565.911 77.910 1.00 29.33 ? 50 GLN A C 1 ATOM 143 O O . GLN A 1 18 ? 105.513 567.026 77.672 1.00 32.05 ? 50 GLN A O 1 ATOM 144 C CB . GLN A 1 18 ? 106.312 564.212 79.196 1.00 30.38 ? 50 GLN A CB 1 ATOM 145 C CG . GLN A 1 18 ? 106.836 563.698 80.538 1.00 27.13 ? 50 GLN A CG 1 ATOM 146 C CD . GLN A 1 18 ? 108.013 564.451 81.048 1.00 33.43 ? 50 GLN A CD 1 ATOM 147 O OE1 . GLN A 1 18 ? 108.782 565.016 80.283 1.00 31.72 ? 50 GLN A OE1 1 ATOM 148 N NE2 . GLN A 1 18 ? 108.162 564.496 82.371 1.00 31.18 ? 50 GLN A NE2 1 ATOM 149 N N . ARG A 1 19 ? 104.403 565.195 77.023 1.00 21.87 ? 51 ARG A N 1 ATOM 150 C CA . ARG A 1 19 ? 104.236 565.657 75.649 1.00 21.43 ? 51 ARG A CA 1 ATOM 151 C C . ARG A 1 19 ? 103.394 566.927 75.515 1.00 27.33 ? 51 ARG A C 1 ATOM 152 O O . ARG A 1 19 ? 103.569 567.677 74.545 1.00 26.16 ? 51 ARG A O 1 ATOM 153 C CB . ARG A 1 19 ? 103.702 564.559 74.754 1.00 20.14 ? 51 ARG A CB 1 ATOM 154 C CG . ARG A 1 19 ? 104.234 564.636 73.334 1.00 29.54 ? 51 ARG A CG 1 ATOM 155 C CD . ARG A 1 19 ? 103.579 563.587 72.457 1.00 31.77 ? 51 ARG A CD 1 ATOM 156 N NE . ARG A 1 19 ? 104.311 563.440 71.204 1.00 23.32 ? 51 ARG A NE 1 ATOM 157 C CZ . ARG A 1 19 ? 103.805 562.958 70.070 1.00 32.47 ? 51 ARG A CZ 1 ATOM 158 N NH1 . ARG A 1 19 ? 102.552 562.522 70.020 1.00 21.06 ? 51 ARG A NH1 1 ATOM 159 N NH2 . ARG A 1 19 ? 104.550 562.896 68.984 1.00 12.44 ? 51 ARG A NH2 1 ATOM 160 N N . SER A 1 20 ? 102.520 567.197 76.501 1.00 25.32 ? 52 SER A N 1 ATOM 161 C CA . SER A 1 20 ? 101.692 568.410 76.527 1.00 25.01 ? 52 SER A CA 1 ATOM 162 C C . SER A 1 20 ? 102.513 569.671 76.815 1.00 30.57 ? 52 SER A C 1 ATOM 163 O O . SER A 1 20 ? 102.033 570.777 76.566 1.00 32.19 ? 52 SER A O 1 ATOM 164 C CB . SER A 1 20 ? 100.543 568.279 77.522 1.00 26.75 ? 52 SER A CB 1 ATOM 165 O OG . SER A 1 20 ? 101.005 568.369 78.860 1.00 25.27 ? 52 SER A OG 1 ATOM 166 N N . ILE A 1 21 ? 103.725 569.518 77.346 1.00 26.96 ? 53 ILE A N 1 ATOM 167 C CA . ILE A 1 21 ? 104.627 570.636 77.590 1.00 27.48 ? 53 ILE A CA 1 ATOM 168 C C . ILE A 1 21 ? 105.202 570.963 76.221 1.00 35.20 ? 53 ILE A C 1 ATOM 169 O O . ILE A 1 21 ? 105.810 570.098 75.564 1.00 34.94 ? 53 ILE A O 1 ATOM 170 C CB . ILE A 1 21 ? 105.743 570.272 78.587 1.00 30.93 ? 53 ILE A CB 1 ATOM 171 C CG1 . ILE A 1 21 ? 105.142 569.876 79.954 1.00 30.73 ? 53 ILE A CG1 1 ATOM 172 C CG2 . ILE A 1 21 ? 106.763 571.445 78.692 1.00 32.17 ? 53 ILE A CG2 1 ATOM 173 C CD1 . ILE A 1 21 ? 106.101 569.309 80.929 1.00 32.24 ? 53 ILE A CD1 1 ATOM 174 N N . ARG A 1 22 ? 104.954 572.183 75.776 1.00 33.88 ? 54 ARG A N 1 ATOM 175 C CA . ARG A 1 22 ? 105.341 572.614 74.466 1.00 34.54 ? 54 ARG A CA 1 ATOM 176 C C . ARG A 1 22 ? 106.519 573.595 74.559 1.00 37.84 ? 54 ARG A C 1 ATOM 177 O O . ARG A 1 22 ? 106.774 574.142 75.646 1.00 36.53 ? 54 ARG A O 1 ATOM 178 C CB . ARG A 1 22 ? 104.103 573.156 73.693 1.00 39.73 ? 54 ARG A CB 1 ATOM 179 C CG . ARG A 1 22 ? 103.628 574.586 74.084 1.00 65.05 ? 54 ARG A CG 1 ATOM 180 C CD . ARG A 1 22 ? 102.852 575.388 72.989 1.00 85.45 ? 54 ARG A CD 1 ATOM 181 N NE . ARG A 1 22 ? 102.716 576.818 73.344 1.00 94.32 ? 54 ARG A NE 1 ATOM 182 C CZ . ARG A 1 22 ? 102.176 577.770 72.579 1.00 98.17 ? 54 ARG A CZ 1 ATOM 183 N NH1 . ARG A 1 22 ? 101.687 577.474 71.379 1.00 81.84 ? 54 ARG A NH1 1 ATOM 184 N NH2 . ARG A 1 22 ? 102.115 579.022 73.013 1.00 73.85 ? 54 ARG A NH2 1 ATOM 185 N N . PRO A 1 23 ? 107.284 573.765 73.443 1.00 34.31 ? 55 PRO A N 1 ATOM 186 C CA . PRO A 1 23 ? 108.454 574.661 73.464 1.00 33.57 ? 55 PRO A CA 1 ATOM 187 C C . PRO A 1 23 ? 108.149 576.048 73.984 1.00 36.79 ? 55 PRO A C 1 ATOM 188 O O . PRO A 1 23 ? 107.149 576.634 73.621 1.00 36.98 ? 55 PRO A O 1 ATOM 189 C CB . PRO A 1 23 ? 108.892 574.699 72.002 1.00 35.21 ? 55 PRO A CB 1 ATOM 190 C CG . PRO A 1 23 ? 108.424 573.403 71.442 1.00 39.14 ? 55 PRO A CG 1 ATOM 191 C CD . PRO A 1 23 ? 107.131 573.124 72.117 1.00 35.26 ? 55 PRO A CD 1 ATOM 192 N N . GLY A 1 24 ? 108.973 576.515 74.884 1.00 33.00 ? 56 GLY A N 1 ATOM 193 C CA . GLY A 1 24 ? 108.788 577.795 75.532 1.00 32.18 ? 56 GLY A CA 1 ATOM 194 C C . GLY A 1 24 ? 109.938 578.075 76.450 1.00 36.22 ? 56 GLY A C 1 ATOM 195 O O . GLY A 1 24 ? 110.980 577.429 76.370 1.00 35.25 ? 56 GLY A O 1 ATOM 196 N N . LEU A 1 25 ? 109.765 579.067 77.287 1.00 35.08 ? 57 LEU A N 1 ATOM 197 C CA . LEU A 1 25 ? 110.739 579.467 78.276 1.00 35.37 ? 57 LEU A CA 1 ATOM 198 C C . LEU A 1 25 ? 110.661 578.468 79.439 1.00 40.22 ? 57 LEU A C 1 ATOM 199 O O . LEU A 1 25 ? 109.567 578.272 79.997 1.00 41.13 ? 57 LEU A O 1 ATOM 200 C CB . LEU A 1 25 ? 110.377 580.864 78.740 1.00 35.77 ? 57 LEU A CB 1 ATOM 201 C CG . LEU A 1 25 ? 111.458 581.608 79.451 1.00 42.34 ? 57 LEU A CG 1 ATOM 202 C CD1 . LEU A 1 25 ? 112.720 581.690 78.575 1.00 43.37 ? 57 LEU A CD1 1 ATOM 203 C CD2 . LEU A 1 25 ? 110.985 583.004 79.824 1.00 45.88 ? 57 LEU A CD2 1 ATOM 204 N N . SER A 1 26 ? 111.787 577.785 79.757 1.00 34.25 ? 58 SER A N 1 ATOM 205 C CA . SER A 1 26 ? 111.776 576.778 80.811 1.00 33.44 ? 58 SER A CA 1 ATOM 206 C C . SER A 1 26 ? 111.551 577.418 82.164 1.00 36.25 ? 58 SER A C 1 ATOM 207 O O . SER A 1 26 ? 112.212 578.417 82.483 1.00 36.01 ? 58 SER A O 1 ATOM 208 C CB . SER A 1 26 ? 113.100 576.020 80.881 1.00 36.05 ? 58 SER A CB 1 ATOM 209 O OG . SER A 1 26 ? 113.073 575.054 81.923 1.00 43.63 ? 58 SER A OG 1 ATOM 210 N N . PRO A 1 27 ? 110.699 576.807 83.015 1.00 29.82 ? 59 PRO A N 1 ATOM 211 C CA . PRO A 1 27 ? 110.564 577.323 84.373 1.00 28.61 ? 59 PRO A CA 1 ATOM 212 C C . PRO A 1 27 ? 111.791 577.042 85.256 1.00 30.90 ? 59 PRO A C 1 ATOM 213 O O . PRO A 1 27 ? 111.832 577.508 86.396 1.00 28.32 ? 59 PRO A O 1 ATOM 214 C CB . PRO A 1 27 ? 109.352 576.562 84.907 1.00 30.07 ? 59 PRO A CB 1 ATOM 215 C CG . PRO A 1 27 ? 109.260 575.357 84.115 1.00 33.48 ? 59 PRO A CG 1 ATOM 216 C CD . PRO A 1 27 ? 109.772 575.680 82.772 1.00 30.01 ? 59 PRO A CD 1 ATOM 217 N N . TYR A 1 28 ? 112.728 576.190 84.777 1.00 28.00 ? 60 TYR A N 1 ATOM 218 C CA . TYR A 1 28 ? 113.914 575.803 85.532 1.00 25.88 ? 60 TYR A CA 1 ATOM 219 C C . TYR A 1 28 ? 114.978 576.804 85.377 1.00 28.36 ? 60 TYR A C 1 ATOM 220 O O . TYR A 1 28 ? 115.232 577.283 84.272 1.00 26.04 ? 60 TYR A O 1 ATOM 221 C CB . TYR A 1 28 ? 114.445 574.412 85.123 1.00 26.04 ? 60 TYR A CB 1 ATOM 222 C CG . TYR A 1 28 ? 113.471 573.315 85.483 1.00 27.46 ? 60 TYR A CG 1 ATOM 223 C CD1 . TYR A 1 28 ? 113.367 572.847 86.792 1.00 29.66 ? 60 TYR A CD1 1 ATOM 224 C CD2 . TYR A 1 28 ? 112.595 572.798 84.537 1.00 26.72 ? 60 TYR A CD2 1 ATOM 225 C CE1 . TYR A 1 28 ? 112.445 571.852 87.134 1.00 29.18 ? 60 TYR A CE1 1 ATOM 226 C CE2 . TYR A 1 28 ? 111.692 571.790 84.864 1.00 26.58 ? 60 TYR A CE2 1 ATOM 227 C CZ . TYR A 1 28 ? 111.610 571.331 86.166 1.00 29.07 ? 60 TYR A CZ 1 ATOM 228 O OH . TYR A 1 28 ? 110.667 570.392 86.492 1.00 29.03 ? 60 TYR A OH 1 ATOM 229 N N . ARG A 1 29 ? 115.614 577.113 86.492 1.00 27.08 ? 61 ARG A N 1 ATOM 230 C CA . ARG A 1 29 ? 116.780 577.970 86.504 1.00 28.40 ? 61 ARG A CA 1 ATOM 231 C C . ARG A 1 29 ? 117.775 577.425 87.483 1.00 32.88 ? 61 ARG A C 1 ATOM 232 O O . ARG A 1 29 ? 117.383 576.785 88.460 1.00 33.44 ? 61 ARG A O 1 ATOM 233 C CB . ARG A 1 29 ? 116.438 579.446 86.798 1.00 30.14 ? 61 ARG A CB 1 ATOM 234 C CG . ARG A 1 29 ? 116.041 579.772 88.224 1.00 41.53 ? 61 ARG A CG 1 ATOM 235 C CD . ARG A 1 29 ? 115.813 581.263 88.384 1.00 57.51 ? 61 ARG A CD 1 ATOM 236 N NE . ARG A 1 29 ? 115.435 581.590 89.761 1.00 73.59 ? 61 ARG A NE 1 ATOM 237 C CZ . ARG A 1 29 ? 116.226 582.191 90.652 1.00 92.35 ? 61 ARG A CZ 1 ATOM 238 N NH1 . ARG A 1 29 ? 117.450 582.582 90.312 1.00 76.04 ? 61 ARG A NH1 1 ATOM 239 N NH2 . ARG A 1 29 ? 115.792 582.419 91.885 1.00 85.41 ? 61 ARG A NH2 1 ATOM 240 N N . ALA A 1 30 ? 119.047 577.690 87.232 1.00 27.55 ? 62 ALA A N 1 ATOM 241 C CA . ALA A 1 30 ? 120.117 577.255 88.100 1.00 27.94 ? 62 ALA A CA 1 ATOM 242 C C . ALA A 1 30 ? 120.375 578.388 89.070 1.00 34.70 ? 62 ALA A C 1 ATOM 243 O O . ALA A 1 30 ? 120.265 579.572 88.711 1.00 33.69 ? 62 ALA A O 1 ATOM 244 C CB . ALA A 1 30 ? 121.373 576.973 87.288 1.00 28.27 ? 62 ALA A CB 1 ATOM 245 N N . LEU A 1 31 ? 120.718 578.023 90.292 1.00 32.44 ? 63 LEU A N 1 ATOM 246 C CA . LEU A 1 31 ? 121.026 578.966 91.346 1.00 32.96 ? 63 LEU A CA 1 ATOM 247 C C . LEU A 1 31 ? 122.535 578.967 91.446 1.00 38.31 ? 63 LEU A C 1 ATOM 248 O O . LEU A 1 31 ? 123.112 578.124 92.123 1.00 37.45 ? 63 LEU A O 1 ATOM 249 C CB . LEU A 1 31 ? 120.358 578.503 92.667 1.00 32.93 ? 63 LEU A CB 1 ATOM 250 C CG . LEU A 1 31 ? 118.829 578.383 92.619 1.00 36.70 ? 63 LEU A CG 1 ATOM 251 C CD1 . LEU A 1 31 ? 118.277 577.737 93.879 1.00 34.53 ? 63 LEU A CD1 1 ATOM 252 C CD2 . LEU A 1 31 ? 118.192 579.730 92.363 1.00 39.89 ? 63 LEU A CD2 1 ATOM 253 N N . LEU A 1 32 ? 123.192 579.879 90.732 1.00 36.02 ? 64 LEU A N 1 ATOM 254 C CA . LEU A 1 32 ? 124.659 579.919 90.680 1.00 35.33 ? 64 LEU A CA 1 ATOM 255 C C . LEU A 1 32 ? 125.356 580.095 92.023 1.00 39.90 ? 64 LEU A C 1 ATOM 256 O O . LEU A 1 32 ? 126.511 579.683 92.154 1.00 39.33 ? 64 LEU A O 1 ATOM 257 C CB . LEU A 1 32 ? 125.145 580.958 89.695 1.00 35.32 ? 64 LEU A CB 1 ATOM 258 C CG . LEU A 1 32 ? 124.686 580.737 88.262 1.00 39.58 ? 64 LEU A CG 1 ATOM 259 C CD1 . LEU A 1 32 ? 125.249 581.821 87.352 1.00 38.33 ? 64 LEU A CD1 1 ATOM 260 C CD2 . LEU A 1 32 ? 125.075 579.325 87.771 1.00 43.19 ? 64 LEU A CD2 1 ATOM 261 N N . ASP A 1 33 ? 124.656 580.632 93.039 1.00 36.87 ? 65 ASP A N 1 ATOM 262 C CA . ASP A 1 33 ? 125.236 580.724 94.379 1.00 36.41 ? 65 ASP A CA 1 ATOM 263 C C . ASP A 1 33 ? 125.473 579.354 95.021 1.00 40.10 ? 65 ASP A C 1 ATOM 264 O O . ASP A 1 33 ? 126.297 579.246 95.923 1.00 42.06 ? 65 ASP A O 1 ATOM 265 C CB . ASP A 1 33 ? 124.377 581.594 95.278 1.00 38.55 ? 65 ASP A CB 1 ATOM 266 C CG . ASP A 1 33 ? 124.481 583.074 94.954 1.00 54.90 ? 65 ASP A CG 1 ATOM 267 O OD1 . ASP A 1 33 ? 125.407 583.461 94.184 1.00 56.21 ? 65 ASP A OD1 1 ATOM 268 O OD2 . ASP A 1 33 ? 123.669 583.852 95.491 1.00 63.23 ? 65 ASP A OD2 1 ATOM 269 N N . THR A 1 34 ? 124.791 578.309 94.552 1.00 33.85 ? 66 THR A N 1 ATOM 270 C CA . THR A 1 34 ? 124.941 576.963 95.103 1.00 32.45 ? 66 THR A CA 1 ATOM 271 C C . THR A 1 34 ? 125.942 576.144 94.351 1.00 35.11 ? 66 THR A C 1 ATOM 272 O O . THR A 1 34 ? 126.137 574.984 94.698 1.00 33.36 ? 66 THR A O 1 ATOM 273 C CB . THR A 1 34 ? 123.617 576.223 95.062 1.00 38.69 ? 66 THR A CB 1 ATOM 274 O OG1 . THR A 1 34 ? 123.248 576.005 93.695 1.00 37.01 ? 66 THR A OG1 1 ATOM 275 C CG2 . THR A 1 34 ? 122.526 576.936 95.832 1.00 35.51 ? 66 THR A CG2 1 ATOM 276 N N . LEU A 1 35 ? 126.550 576.723 93.306 1.00 33.93 ? 67 LEU A N 1 ATOM 277 C CA . LEU A 1 35 ? 127.495 576.018 92.460 1.00 34.33 ? 67 LEU A CA 1 ATOM 278 C C . LEU A 1 35 ? 128.735 575.596 93.249 1.00 37.37 ? 67 LEU A C 1 ATOM 279 O O . LEU A 1 35 ? 129.306 576.381 94.017 1.00 34.32 ? 67 LEU A O 1 ATOM 280 C CB . LEU A 1 35 ? 127.866 576.886 91.250 1.00 34.94 ? 67 LEU A CB 1 ATOM 281 C CG . LEU A 1 35 ? 128.712 576.229 90.158 1.00 40.79 ? 67 LEU A CG 1 ATOM 282 C CD1 . LEU A 1 35 ? 128.414 576.848 88.821 1.00 40.80 ? 67 LEU A CD1 1 ATOM 283 C CD2 . LEU A 1 35 ? 130.224 576.341 90.452 1.00 43.88 ? 67 LEU A CD2 1 ATOM 284 N N . GLN A 1 36 ? 129.132 574.336 93.042 1.00 34.59 ? 68 GLN A N 1 ATOM 285 C CA . GLN A 1 36 ? 130.291 573.723 93.661 1.00 34.09 ? 68 GLN A CA 1 ATOM 286 C C . GLN A 1 36 ? 131.066 573.023 92.595 1.00 40.20 ? 68 GLN A C 1 ATOM 287 O O . GLN A 1 36 ? 130.507 572.273 91.794 1.00 39.19 ? 68 GLN A O 1 ATOM 288 C CB . GLN A 1 36 ? 129.870 572.741 94.753 1.00 34.73 ? 68 GLN A CB 1 ATOM 289 C CG . GLN A 1 36 ? 129.247 573.449 95.943 1.00 45.73 ? 68 GLN A CG 1 ATOM 290 C CD . GLN A 1 36 ? 128.968 572.477 97.045 1.00 62.03 ? 68 GLN A CD 1 ATOM 291 O OE1 . GLN A 1 36 ? 127.899 571.861 97.091 1.00 64.09 ? 68 GLN A OE1 1 ATOM 292 N NE2 . GLN A 1 36 ? 129.941 572.278 97.932 1.00 38.15 ? 68 GLN A NE2 1 ATOM 293 N N . LEU A 1 37 ? 132.361 573.271 92.572 1.00 38.65 ? 69 LEU A N 1 ATOM 294 C CA . LEU A 1 37 ? 133.199 572.648 91.581 1.00 37.83 ? 69 LEU A CA 1 ATOM 295 C C . LEU A 1 37 ? 134.281 571.841 92.248 1.00 40.78 ? 69 LEU A C 1 ATOM 296 O O . LEU A 1 37 ? 134.993 572.334 93.118 1.00 39.96 ? 69 LEU A O 1 ATOM 297 C CB . LEU A 1 37 ? 133.776 573.733 90.662 1.00 37.46 ? 69 LEU A CB 1 ATOM 298 C CG . LEU A 1 37 ? 134.603 573.257 89.495 1.00 41.56 ? 69 LEU A CG 1 ATOM 299 C CD1 . LEU A 1 37 ? 133.808 572.312 88.599 1.00 40.94 ? 69 LEU A CD1 1 ATOM 300 C CD2 . LEU A 1 37 ? 135.172 574.445 88.725 1.00 43.88 ? 69 LEU A CD2 1 ATOM 301 N N . GLY A 1 38 ? 134.370 570.596 91.834 1.00 39.18 ? 70 GLY A N 1 ATOM 302 C CA . GLY A 1 38 ? 135.383 569.651 92.274 1.00 40.62 ? 70 GLY A CA 1 ATOM 303 C C . GLY A 1 38 ? 136.202 569.119 91.106 1.00 47.74 ? 70 GLY A C 1 ATOM 304 O O . GLY A 1 38 ? 135.956 569.467 89.944 1.00 47.88 ? 70 GLY A O 1 ATOM 305 N N . PRO A 1 39 ? 137.168 568.230 91.395 1.00 45.68 ? 71 PRO A N 1 ATOM 306 C CA . PRO A 1 39 ? 137.998 567.664 90.315 1.00 45.64 ? 71 PRO A CA 1 ATOM 307 C C . PRO A 1 39 ? 137.231 566.741 89.371 1.00 46.87 ? 71 PRO A C 1 ATOM 308 O O . PRO A 1 39 ? 137.577 566.640 88.189 1.00 46.53 ? 71 PRO A O 1 ATOM 309 C CB . PRO A 1 39 ? 139.090 566.888 91.066 1.00 47.51 ? 71 PRO A CB 1 ATOM 310 C CG . PRO A 1 39 ? 138.536 566.634 92.418 1.00 52.09 ? 71 PRO A CG 1 ATOM 311 C CD . PRO A 1 39 ? 137.526 567.681 92.716 1.00 47.47 ? 71 PRO A CD 1 ATOM 312 N N . ASP A 1 40 ? 136.194 566.078 89.896 1.00 41.02 ? 72 ASP A N 1 ATOM 313 C CA . ASP A 1 40 ? 135.410 565.086 89.167 1.00 40.62 ? 72 ASP A CA 1 ATOM 314 C C . ASP A 1 40 ? 134.062 565.564 88.643 1.00 42.64 ? 72 ASP A C 1 ATOM 315 O O . ASP A 1 40 ? 133.549 565.000 87.672 1.00 42.23 ? 72 ASP A O 1 ATOM 316 C CB . ASP A 1 40 ? 135.213 563.826 90.045 1.00 43.06 ? 72 ASP A CB 1 ATOM 317 C CG . ASP A 1 40 ? 136.501 563.072 90.385 1.00 53.29 ? 72 ASP A CG 1 ATOM 318 O OD1 . ASP A 1 40 ? 137.210 562.640 89.448 1.00 53.66 ? 72 ASP A OD1 1 ATOM 319 O OD2 . ASP A 1 40 ? 136.797 562.921 91.582 1.00 61.58 ? 72 ASP A OD2 1 ATOM 320 N N . ALA A 1 41 ? 133.478 566.584 89.290 1.00 37.80 ? 73 ALA A N 1 ATOM 321 C CA . ALA A 1 41 ? 132.149 567.091 88.944 1.00 34.99 ? 73 ALA A CA 1 ATOM 322 C C . ALA A 1 41 ? 131.936 568.534 89.312 1.00 34.46 ? 73 ALA A C 1 ATOM 323 O O . ALA A 1 41 ? 132.614 569.084 90.169 1.00 33.77 ? 73 ALA A O 1 ATOM 324 C CB . ALA A 1 41 ? 131.108 566.258 89.677 1.00 35.33 ? 73 ALA A CB 1 ATOM 325 N N . LEU A 1 42 ? 130.944 569.119 88.680 1.00 30.36 ? 74 LEU A N 1 ATOM 326 C CA . LEU A 1 42 ? 130.328 570.392 89.023 1.00 30.12 ? 74 LEU A CA 1 ATOM 327 C C . LEU A 1 42 ? 128.932 570.015 89.504 1.00 35.59 ? 74 LEU A C 1 ATOM 328 O O . LEU A 1 42 ? 128.225 569.242 88.836 1.00 33.42 ? 74 LEU A O 1 ATOM 329 C CB . LEU A 1 42 ? 130.180 571.313 87.811 1.00 29.35 ? 74 LEU A CB 1 ATOM 330 C CG . LEU A 1 42 ? 129.591 572.701 88.073 1.00 33.71 ? 74 LEU A CG 1 ATOM 331 C CD1 . LEU A 1 42 ? 130.273 573.716 87.204 1.00 33.23 ? 74 LEU A CD1 1 ATOM 332 C CD2 . LEU A 1 42 ? 128.058 572.750 87.863 1.00 36.19 ? 74 LEU A CD2 1 ATOM 333 N N . THR A 1 43 ? 128.510 570.576 90.633 1.00 34.52 ? 75 THR A N 1 ATOM 334 C CA . THR A 1 43 ? 127.115 570.439 91.065 1.00 33.67 ? 75 THR A CA 1 ATOM 335 C C . THR A 1 43 ? 126.510 571.822 91.238 1.00 35.34 ? 75 THR A C 1 ATOM 336 O O . THR A 1 43 ? 127.204 572.777 91.597 1.00 34.60 ? 75 THR A O 1 ATOM 337 C CB . THR A 1 43 ? 126.924 569.629 92.327 1.00 38.89 ? 75 THR A CB 1 ATOM 338 O OG1 . THR A 1 43 ? 127.585 570.284 93.399 1.00 41.86 ? 75 THR A OG1 1 ATOM 339 C CG2 . THR A 1 43 ? 127.401 568.226 92.185 1.00 38.29 ? 75 THR A CG2 1 ATOM 340 N N . VAL A 1 44 ? 125.205 571.913 91.033 1.00 30.92 ? 76 VAL A N 1 ATOM 341 C CA . VAL A 1 44 ? 124.469 573.152 91.233 1.00 29.89 ? 76 VAL A CA 1 ATOM 342 C C . VAL A 1 44 ? 123.016 572.825 91.426 1.00 34.96 ? 76 VAL A C 1 ATOM 343 O O . VAL A 1 44 ? 122.540 571.834 90.874 1.00 37.07 ? 76 VAL A O 1 ATOM 344 C CB . VAL A 1 44 ? 124.718 574.157 90.095 1.00 31.86 ? 76 VAL A CB 1 ATOM 345 C CG1 . VAL A 1 44 ? 124.194 573.634 88.754 1.00 31.24 ? 76 VAL A CG1 1 ATOM 346 C CG2 . VAL A 1 44 ? 124.146 575.516 90.443 1.00 31.30 ? 76 VAL A CG2 1 ATOM 347 N N . HIS A 1 45 ? 122.312 573.641 92.199 1.00 29.33 ? 77 HIS A N 1 ATOM 348 C CA . HIS A 1 45 ? 120.903 573.429 92.436 1.00 28.96 ? 77 HIS A CA 1 ATOM 349 C C . HIS A 1 45 ? 120.117 574.077 91.322 1.00 33.10 ? 77 HIS A C 1 ATOM 350 O O . HIS A 1 45 ? 120.506 575.123 90.809 1.00 32.87 ? 77 HIS A O 1 ATOM 351 C CB . HIS A 1 45 ? 120.480 574.018 93.794 1.00 29.80 ? 77 HIS A CB 1 ATOM 352 C CG . HIS A 1 45 ? 121.114 573.371 94.993 1.00 33.38 ? 77 HIS A CG 1 ATOM 353 N ND1 . HIS A 1 45 ? 120.692 573.677 96.274 1.00 35.45 ? 77 HIS A ND1 1 ATOM 354 C CD2 . HIS A 1 45 ? 122.107 572.453 95.076 1.00 35.41 ? 77 HIS A CD2 1 ATOM 355 C CE1 . HIS A 1 45 ? 121.437 572.940 97.092 1.00 34.87 ? 77 HIS A CE1 1 ATOM 356 N NE2 . HIS A 1 45 ? 122.318 572.205 96.422 1.00 35.18 ? 77 HIS A NE2 1 ATOM 357 N N . LEU A 1 46 ? 119.017 573.449 90.930 1.00 29.07 ? 78 LEU A N 1 ATOM 358 C CA . LEU A 1 46 ? 118.088 574.001 89.950 1.00 27.52 ? 78 LEU A CA 1 ATOM 359 C C . LEU A 1 46 ? 116.807 574.116 90.693 1.00 29.01 ? 78 LEU A C 1 ATOM 360 O O . LEU A 1 46 ? 116.569 573.325 91.612 1.00 26.54 ? 78 LEU A O 1 ATOM 361 C CB . LEU A 1 46 ? 117.872 573.080 88.715 1.00 27.16 ? 78 LEU A CB 1 ATOM 362 C CG . LEU A 1 46 ? 119.097 572.560 87.965 1.00 30.06 ? 78 LEU A CG 1 ATOM 363 C CD1 . LEU A 1 46 ? 118.689 571.653 86.801 1.00 30.28 ? 78 LEU A CD1 1 ATOM 364 C CD2 . LEU A 1 46 ? 119.939 573.673 87.459 1.00 30.25 ? 78 LEU A CD2 1 ATOM 365 N N . ILE A 1 47 ? 115.978 575.082 90.309 1.00 26.87 ? 79 ILE A N 1 ATOM 366 C CA . ILE A 1 47 ? 114.660 575.269 90.910 1.00 26.78 ? 79 ILE A CA 1 ATOM 367 C C . ILE A 1 47 ? 113.598 575.476 89.838 1.00 31.98 ? 79 ILE A C 1 ATOM 368 O O . ILE A 1 47 ? 113.843 576.173 88.861 1.00 32.71 ? 79 ILE A O 1 ATOM 369 C CB . ILE A 1 47 ? 114.659 576.423 91.970 1.00 29.41 ? 79 ILE A CB 1 ATOM 370 C CG1 . ILE A 1 47 ? 113.341 576.465 92.779 1.00 29.56 ? 79 ILE A CG1 1 ATOM 371 C CG2 . ILE A 1 47 ? 115.007 577.803 91.353 1.00 28.05 ? 79 ILE A CG2 1 ATOM 372 C CD1 . ILE A 1 47 ? 113.332 577.388 93.986 1.00 35.47 ? 79 ILE A CD1 1 ATOM 373 N N . HIS A 1 48 ? 112.411 574.913 90.043 1.00 28.93 ? 80 HIS A N 1 ATOM 374 C CA . HIS A 1 48 ? 111.285 575.181 89.170 1.00 29.49 ? 80 HIS A CA 1 ATOM 375 C C . HIS A 1 48 ? 110.703 576.499 89.750 1.00 34.64 ? 80 HIS A C 1 ATOM 376 O O . HIS A 1 48 ? 110.389 576.556 90.942 1.00 34.51 ? 80 HIS A O 1 ATOM 377 C CB . HIS A 1 48 ? 110.292 574.036 89.280 1.00 30.94 ? 80 HIS A CB 1 ATOM 378 C CG . HIS A 1 48 ? 109.175 574.086 88.285 1.00 35.06 ? 80 HIS A CG 1 ATOM 379 N ND1 . HIS A 1 48 ? 108.242 575.104 88.295 1.00 36.95 ? 80 HIS A ND1 1 ATOM 380 C CD2 . HIS A 1 48 ? 108.848 573.206 87.313 1.00 36.99 ? 80 HIS A CD2 1 ATOM 381 C CE1 . HIS A 1 48 ? 107.390 574.819 87.330 1.00 36.55 ? 80 HIS A CE1 1 ATOM 382 N NE2 . HIS A 1 48 ? 107.710 573.687 86.713 1.00 36.90 ? 80 HIS A NE2 1 ATOM 383 N N . GLU A 1 49 ? 110.638 577.572 88.949 1.00 31.64 ? 81 GLU A N 1 ATOM 384 C CA . GLU A 1 49 ? 110.164 578.878 89.442 1.00 32.15 ? 81 GLU A CA 1 ATOM 385 C C . GLU A 1 49 ? 108.740 578.865 90.031 1.00 37.38 ? 81 GLU A C 1 ATOM 386 O O . GLU A 1 49 ? 108.456 579.684 90.900 1.00 38.88 ? 81 GLU A O 1 ATOM 387 C CB . GLU A 1 49 ? 110.296 579.993 88.387 1.00 33.54 ? 81 GLU A CB 1 ATOM 388 C CG . GLU A 1 49 ? 109.342 579.931 87.194 1.00 45.17 ? 81 GLU A CG 1 ATOM 389 C CD . GLU A 1 49 ? 109.467 581.115 86.249 1.00 70.65 ? 81 GLU A CD 1 ATOM 390 O OE1 . GLU A 1 49 ? 110.609 581.434 85.837 1.00 76.34 ? 81 GLU A OE1 1 ATOM 391 O OE2 . GLU A 1 49 ? 108.421 581.719 85.913 1.00 50.64 ? 81 GLU A OE2 1 ATOM 392 N N . VAL A 1 50 ? 107.855 577.967 89.561 1.00 31.42 ? 82 VAL A N 1 ATOM 393 C CA . VAL A 1 50 ? 106.477 577.902 90.045 1.00 30.71 ? 82 VAL A CA 1 ATOM 394 C C . VAL A 1 50 ? 106.339 577.060 91.329 1.00 36.01 ? 82 VAL A C 1 ATOM 395 O O . VAL A 1 50 ? 105.847 577.569 92.343 1.00 34.96 ? 82 VAL A O 1 ATOM 396 C CB . VAL A 1 50 ? 105.492 577.441 88.927 1.00 33.36 ? 82 VAL A CB 1 ATOM 397 C CG1 . VAL A 1 50 ? 104.069 577.291 89.457 1.00 33.25 ? 82 VAL A CG1 1 ATOM 398 C CG2 . VAL A 1 50 ? 105.518 578.404 87.745 1.00 32.43 ? 82 VAL A CG2 1 ATOM 399 N N . THR A 1 51 ? 106.704 575.766 91.262 1.00 32.89 ? 83 THR A N 1 ATOM 400 C CA . THR A 1 51 ? 106.541 574.832 92.385 1.00 31.47 ? 83 THR A CA 1 ATOM 401 C C . THR A 1 51 ? 107.586 574.974 93.477 1.00 33.54 ? 83 THR A C 1 ATOM 402 O O . THR A 1 51 ? 107.385 574.458 94.573 1.00 33.25 ? 83 THR A O 1 ATOM 403 C CB . THR A 1 51 ? 106.576 573.403 91.891 1.00 37.79 ? 83 THR A CB 1 ATOM 404 O OG1 . THR A 1 51 ? 107.907 573.134 91.460 1.00 42.81 ? 83 THR A OG1 1 ATOM 405 C CG2 . THR A 1 51 ? 105.557 573.127 90.780 1.00 32.83 ? 83 THR A CG2 1 ATOM 406 N N . LYS A 1 52 ? 108.721 575.599 93.174 1.00 30.05 ? 84 LYS A N 1 ATOM 407 C CA . LYS A 1 52 ? 109.859 575.813 94.088 1.00 30.28 ? 84 LYS A CA 1 ATOM 408 C C . LYS A 1 52 ? 110.589 574.510 94.449 1.00 36.98 ? 84 LYS A C 1 ATOM 409 O O . LYS A 1 52 ? 111.391 574.487 95.401 1.00 37.31 ? 84 LYS A O 1 ATOM 410 C CB . LYS A 1 52 ? 109.515 576.635 95.357 1.00 31.78 ? 84 LYS A CB 1 ATOM 411 C CG . LYS A 1 52 ? 108.663 577.889 95.121 1.00 43.31 ? 84 LYS A CG 1 ATOM 412 C CD . LYS A 1 52 ? 109.343 578.927 94.250 1.00 45.57 ? 84 LYS A CD 1 ATOM 413 C CE . LYS A 1 52 ? 108.501 580.172 94.168 1.00 46.73 ? 84 LYS A CE 1 ATOM 414 N NZ . LYS A 1 52 ? 109.143 581.205 93.308 1.00 47.37 ? 84 LYS A NZ 1 ATOM 415 N N . VAL A 1 53 ? 110.361 573.445 93.643 1.00 33.11 ? 85 VAL A N 1 ATOM 416 C CA . VAL A 1 53 ? 111.039 572.159 93.817 1.00 31.76 ? 85 VAL A CA 1 ATOM 417 C C . VAL A 1 53 ? 112.497 572.353 93.486 1.00 33.19 ? 85 VAL A C 1 ATOM 418 O O . VAL A 1 53 ? 112.835 572.936 92.449 1.00 31.11 ? 85 VAL A O 1 ATOM 419 C CB . VAL A 1 53 ? 110.414 571.058 92.931 1.00 35.45 ? 85 VAL A CB 1 ATOM 420 C CG1 . VAL A 1 53 ? 111.347 569.846 92.778 1.00 35.28 ? 85 VAL A CG1 1 ATOM 421 C CG2 . VAL A 1 53 ? 109.062 570.646 93.474 1.00 34.82 ? 85 VAL A CG2 1 ATOM 422 N N . LEU A 1 54 ? 113.354 571.821 94.348 1.00 29.79 ? 86 LEU A N 1 ATOM 423 C CA . LEU A 1 54 ? 114.795 571.904 94.144 1.00 29.71 ? 86 LEU A CA 1 ATOM 424 C C . LEU A 1 54 ? 115.383 570.583 93.602 1.00 31.02 ? 86 LEU A C 1 ATOM 425 O O . LEU A 1 54 ? 115.069 569.501 94.091 1.00 29.60 ? 86 LEU A O 1 ATOM 426 C CB . LEU A 1 54 ? 115.491 572.308 95.454 1.00 30.19 ? 86 LEU A CB 1 ATOM 427 C CG . LEU A 1 54 ? 115.292 573.749 95.907 1.00 33.99 ? 86 LEU A CG 1 ATOM 428 C CD1 . LEU A 1 54 ? 115.428 573.858 97.421 1.00 34.44 ? 86 LEU A CD1 1 ATOM 429 C CD2 . LEU A 1 54 ? 116.251 574.675 95.180 1.00 31.88 ? 86 LEU A CD2 1 ATOM 430 N N . LEU A 1 55 ? 116.235 570.705 92.585 1.00 26.66 ? 87 LEU A N 1 ATOM 431 C CA . LEU A 1 55 ? 116.934 569.617 91.924 1.00 25.29 ? 87 LEU A CA 1 ATOM 432 C C . LEU A 1 55 ? 118.387 569.894 91.985 1.00 29.15 ? 87 LEU A C 1 ATOM 433 O O . LEU A 1 55 ? 118.779 571.029 92.174 1.00 30.73 ? 87 LEU A O 1 ATOM 434 C CB . LEU A 1 55 ? 116.519 569.539 90.456 1.00 25.25 ? 87 LEU A CB 1 ATOM 435 C CG . LEU A 1 55 ? 115.010 569.468 90.174 1.00 29.07 ? 87 LEU A CG 1 ATOM 436 C CD1 . LEU A 1 55 ? 114.734 569.509 88.688 1.00 30.23 ? 87 LEU A CD1 1 ATOM 437 C CD2 . LEU A 1 55 ? 114.381 568.247 90.808 1.00 28.46 ? 87 LEU A CD2 1 ATOM 438 N N . VAL A 1 56 ? 119.200 568.872 91.824 1.00 25.79 ? 88 VAL A N 1 ATOM 439 C CA . VAL A 1 56 ? 120.655 568.983 91.782 1.00 23.84 ? 88 VAL A CA 1 ATOM 440 C C . VAL A 1 56 ? 121.119 568.501 90.425 1.00 29.15 ? 88 VAL A C 1 ATOM 441 O O . VAL A 1 56 ? 120.858 567.357 90.052 1.00 27.97 ? 88 VAL A O 1 ATOM 442 C CB . VAL A 1 56 ? 121.341 568.152 92.892 1.00 24.69 ? 88 VAL A CB 1 ATOM 443 C CG1 . VAL A 1 56 ? 122.855 568.284 92.821 1.00 24.24 ? 88 VAL A CG1 1 ATOM 444 C CG2 . VAL A 1 56 ? 120.857 568.589 94.244 1.00 23.84 ? 88 VAL A CG2 1 ATOM 445 N N . LEU A 1 57 ? 121.860 569.353 89.723 1.00 27.61 ? 89 LEU A N 1 ATOM 446 C CA . LEU A 1 57 ? 122.536 568.996 88.501 1.00 27.00 ? 89 LEU A CA 1 ATOM 447 C C . LEU A 1 57 ? 123.963 568.565 88.870 1.00 34.35 ? 89 LEU A C 1 ATOM 448 O O . LEU A 1 57 ? 124.658 569.289 89.590 1.00 35.72 ? 89 LEU A O 1 ATOM 449 C CB . LEU A 1 57 ? 122.582 570.202 87.554 1.00 25.81 ? 89 LEU A CB 1 ATOM 450 C CG . LEU A 1 57 ? 123.504 570.111 86.326 1.00 27.73 ? 89 LEU A CG 1 ATOM 451 C CD1 . LEU A 1 57 ? 123.097 568.977 85.430 1.00 27.72 ? 89 LEU A CD1 1 ATOM 452 C CD2 . LEU A 1 57 ? 123.487 571.389 85.551 1.00 24.41 ? 89 LEU A CD2 1 ATOM 453 N N . GLU A 1 58 ? 124.378 567.380 88.405 1.00 29.30 ? 90 GLU A N 1 ATOM 454 C CA . GLU A 1 58 ? 125.761 566.935 88.510 1.00 29.00 ? 90 GLU A CA 1 ATOM 455 C C . GLU A 1 58 ? 126.261 566.861 87.072 1.00 32.95 ? 90 GLU A C 1 ATOM 456 O O . GLU A 1 58 ? 125.779 566.048 86.275 1.00 33.08 ? 90 GLU A O 1 ATOM 457 C CB . GLU A 1 58 ? 125.896 565.595 89.205 1.00 30.55 ? 90 GLU A CB 1 ATOM 458 C CG . GLU A 1 58 ? 127.339 565.132 89.354 1.00 37.47 ? 90 GLU A CG 1 ATOM 459 C CD . GLU A 1 58 ? 127.512 563.871 90.191 1.00 52.57 ? 90 GLU A CD 1 ATOM 460 O OE1 . GLU A 1 58 ? 126.492 563.279 90.610 1.00 42.72 ? 90 GLU A OE1 1 ATOM 461 O OE2 . GLU A 1 58 ? 128.673 563.462 90.421 1.00 36.38 ? 90 GLU A OE2 1 ATOM 462 N N . LEU A 1 59 ? 127.163 567.759 86.729 1.00 28.13 ? 91 LEU A N 1 ATOM 463 C CA . LEU A 1 59 ? 127.715 567.896 85.393 1.00 27.83 ? 91 LEU A CA 1 ATOM 464 C C . LEU A 1 59 ? 129.149 567.445 85.425 1.00 31.36 ? 91 LEU A C 1 ATOM 465 O O . LEU A 1 59 ? 129.930 567.901 86.261 1.00 30.52 ? 91 LEU A O 1 ATOM 466 C CB . LEU A 1 59 ? 127.620 569.373 84.970 1.00 27.64 ? 91 LEU A CB 1 ATOM 467 C CG . LEU A 1 59 ? 128.205 569.804 83.625 1.00 30.70 ? 91 LEU A CG 1 ATOM 468 C CD1 . LEU A 1 59 ? 127.435 569.235 82.475 1.00 29.69 ? 91 LEU A CD1 1 ATOM 469 C CD2 . LEU A 1 59 ? 128.188 571.298 83.526 1.00 33.09 ? 91 LEU A CD2 1 ATOM 470 N N . GLN A 1 60 ? 129.489 566.533 84.532 1.00 27.88 ? 92 GLN A N 1 ATOM 471 C CA . GLN A 1 60 ? 130.835 566.012 84.461 1.00 26.69 ? 92 GLN A CA 1 ATOM 472 C C . GLN A 1 60 ? 131.394 565.987 83.058 1.00 29.53 ? 92 GLN A C 1 ATOM 473 O O . GLN A 1 60 ? 130.725 565.571 82.108 1.00 30.33 ? 92 GLN A O 1 ATOM 474 C CB . GLN A 1 60 ? 130.879 564.589 85.032 1.00 27.72 ? 92 GLN A CB 1 ATOM 475 C CG . GLN A 1 60 ? 130.464 564.500 86.475 1.00 34.04 ? 92 GLN A CG 1 ATOM 476 C CD . GLN A 1 60 ? 130.444 563.078 86.944 1.00 45.97 ? 92 GLN A CD 1 ATOM 477 O OE1 . GLN A 1 60 ? 129.445 562.365 86.787 1.00 40.92 ? 92 GLN A OE1 1 ATOM 478 N NE2 . GLN A 1 60 ? 131.537 562.641 87.554 1.00 29.33 ? 92 GLN A NE2 1 ATOM 479 N N . GLY A 1 61 ? 132.644 566.387 82.959 1.00 25.52 ? 93 GLY A N 1 ATOM 480 C CA . GLY A 1 61 ? 133.448 566.203 81.767 1.00 25.26 ? 93 GLY A CA 1 ATOM 481 C C . GLY A 1 61 ? 134.026 564.814 81.944 1.00 29.67 ? 93 GLY A C 1 ATOM 482 O O . GLY A 1 61 ? 134.314 564.411 83.076 1.00 28.92 ? 93 GLY A O 1 ATOM 483 N N . LEU A 1 62 ? 134.143 564.047 80.859 1.00 26.57 ? 94 LEU A N 1 ATOM 484 C CA . LEU A 1 62 ? 134.691 562.692 80.929 1.00 26.09 ? 94 LEU A CA 1 ATOM 485 C C . LEU A 1 62 ? 135.777 562.516 79.914 1.00 30.40 ? 94 LEU A C 1 ATOM 486 O O . LEU A 1 62 ? 135.760 563.157 78.855 1.00 29.31 ? 94 LEU A O 1 ATOM 487 C CB . LEU A 1 62 ? 133.600 561.638 80.662 1.00 25.57 ? 94 LEU A CB 1 ATOM 488 C CG . LEU A 1 62 ? 132.391 561.610 81.570 1.00 27.91 ? 94 LEU A CG 1 ATOM 489 C CD1 . LEU A 1 62 ? 131.359 560.657 81.050 1.00 27.25 ? 94 LEU A CD1 1 ATOM 490 C CD2 . LEU A 1 62 ? 132.769 561.234 82.988 1.00 28.53 ? 94 LEU A CD2 1 ATOM 491 N N . GLN A 1 63 ? 136.706 561.607 80.208 1.00 28.34 ? 95 GLN A N 1 ATOM 492 C CA . GLN A 1 63 ? 137.757 561.225 79.260 1.00 28.39 ? 95 GLN A CA 1 ATOM 493 C C . GLN A 1 63 ? 137.073 560.678 78.014 1.00 32.88 ? 95 GLN A C 1 ATOM 494 O O . GLN A 1 63 ? 135.932 560.187 78.091 1.00 32.43 ? 95 GLN A O 1 ATOM 495 C CB . GLN A 1 63 ? 138.639 560.113 79.835 1.00 29.18 ? 95 GLN A CB 1 ATOM 496 C CG . GLN A 1 63 ? 139.495 560.499 81.033 1.00 31.44 ? 95 GLN A CG 1 ATOM 497 C CD . GLN A 1 63 ? 140.402 561.655 80.746 1.00 56.23 ? 95 GLN A CD 1 ATOM 498 O OE1 . GLN A 1 63 ? 141.079 561.722 79.722 1.00 58.67 ? 95 GLN A OE1 1 ATOM 499 N NE2 . GLN A 1 63 ? 140.417 562.611 81.640 1.00 48.79 ? 95 GLN A NE2 1 ATOM 500 N N . LYS A 1 64 ? 137.767 560.783 76.873 1.00 28.56 ? 96 LYS A N 1 ATOM 501 C CA . LYS A 1 64 ? 137.290 560.297 75.588 1.00 28.37 ? 96 LYS A CA 1 ATOM 502 C C . LYS A 1 64 ? 136.151 561.146 75.030 1.00 32.78 ? 96 LYS A C 1 ATOM 503 O O . LYS A 1 64 ? 135.255 560.605 74.391 1.00 33.22 ? 96 LYS A O 1 ATOM 504 C CB . LYS A 1 64 ? 136.901 558.782 75.628 1.00 31.74 ? 96 LYS A CB 1 ATOM 505 C CG . LYS A 1 64 ? 137.954 557.831 76.196 1.00 39.08 ? 96 LYS A CG 1 ATOM 506 C CD . LYS A 1 64 ? 137.680 556.405 75.779 1.00 49.45 ? 96 LYS A CD 1 ATOM 507 C CE . LYS A 1 64 ? 138.018 555.403 76.867 1.00 72.13 ? 96 LYS A CE 1 ATOM 508 N NZ . LYS A 1 64 ? 139.349 554.782 76.656 1.00 89.23 ? 96 LYS A NZ 1 ATOM 509 N N . ASN A 1 65 ? 136.176 562.473 75.249 1.00 27.98 ? 97 ASN A N 1 ATOM 510 C CA . ASN A 1 65 ? 135.210 563.391 74.632 1.00 25.21 ? 97 ASN A CA 1 ATOM 511 C C . ASN A 1 65 ? 133.729 563.147 74.974 1.00 25.86 ? 97 ASN A C 1 ATOM 512 O O . ASN A 1 65 ? 132.858 563.152 74.092 1.00 22.84 ? 97 ASN A O 1 ATOM 513 C CB . ASN A 1 65 ? 135.406 563.355 73.127 1.00 20.43 ? 97 ASN A CB 1 ATOM 514 C CG . ASN A 1 65 ? 136.790 563.712 72.660 1.00 38.30 ? 97 ASN A CG 1 ATOM 515 O OD1 . ASN A 1 65 ? 137.599 564.240 73.416 1.00 37.52 ? 97 ASN A OD1 1 ATOM 516 N ND2 . ASN A 1 65 ? 137.072 563.443 71.385 1.00 28.33 ? 97 ASN A ND2 1 ATOM 517 N N . MET A 1 66 ? 133.435 562.948 76.247 1.00 22.03 ? 98 MET A N 1 ATOM 518 C CA . MET A 1 66 ? 132.048 562.722 76.632 1.00 20.76 ? 98 MET A CA 1 ATOM 519 C C . MET A 1 66 ? 131.701 563.668 77.741 1.00 26.31 ? 98 MET A C 1 ATOM 520 O O . MET A 1 66 ? 132.596 564.184 78.405 1.00 26.51 ? 98 MET A O 1 ATOM 521 C CB . MET A 1 66 ? 131.779 561.255 77.078 1.00 22.28 ? 98 MET A CB 1 ATOM 522 C CG . MET A 1 66 ? 132.084 560.182 76.037 1.00 24.98 ? 98 MET A CG 1 ATOM 523 S SD . MET A 1 66 ? 131.632 558.537 76.688 1.00 26.83 ? 98 MET A SD 1 ATOM 524 C CE . MET A 1 66 ? 133.056 558.151 77.606 1.00 22.31 ? 98 MET A CE 1 ATOM 525 N N . THR A 1 67 ? 130.399 563.876 77.950 1.00 22.96 ? 99 THR A N 1 ATOM 526 C CA . THR A 1 67 ? 129.879 564.703 79.003 1.00 23.41 ? 99 THR A CA 1 ATOM 527 C C . THR A 1 67 ? 128.754 563.928 79.663 1.00 28.93 ? 99 THR A C 1 ATOM 528 O O . THR A 1 67 ? 127.935 563.330 78.967 1.00 31.65 ? 99 THR A O 1 ATOM 529 C CB . THR A 1 67 ? 129.429 566.072 78.437 1.00 28.50 ? 99 THR A CB 1 ATOM 530 O OG1 . THR A 1 67 ? 130.575 566.778 77.945 1.00 27.45 ? 99 THR A OG1 1 ATOM 531 C CG2 . THR A 1 67 ? 128.722 566.935 79.493 1.00 21.54 ? 99 THR A CG2 1 ATOM 532 N N . ARG A 1 68 ? 128.700 563.929 80.990 1.00 23.01 ? 100 ARG A N 1 ATOM 533 C CA . ARG A 1 68 ? 127.603 563.289 81.697 1.00 22.99 ? 100 ARG A CA 1 ATOM 534 C C . ARG A 1 68 ? 126.783 564.338 82.466 1.00 27.71 ? 100 ARG A C 1 ATOM 535 O O . ARG A 1 68 ? 127.344 565.207 83.152 1.00 27.82 ? 100 ARG A O 1 ATOM 536 C CB . ARG A 1 68 ? 128.109 562.197 82.638 1.00 23.05 ? 100 ARG A CB 1 ATOM 537 C CG . ARG A 1 68 ? 127.004 561.328 83.217 1.00 22.01 ? 100 ARG A CG 1 ATOM 538 C CD . ARG A 1 68 ? 127.562 560.334 84.196 1.00 23.51 ? 100 ARG A CD 1 ATOM 539 N NE . ARG A 1 68 ? 126.602 559.291 84.548 1.00 24.55 ? 100 ARG A NE 1 ATOM 540 C CZ . ARG A 1 68 ? 126.877 558.227 85.294 1.00 34.26 ? 100 ARG A CZ 1 ATOM 541 N NH1 . ARG A 1 68 ? 128.111 558.020 85.742 1.00 26.07 ? 100 ARG A NH1 1 ATOM 542 N NH2 . ARG A 1 68 ? 125.936 557.339 85.558 1.00 24.24 ? 100 ARG A NH2 1 ATOM 543 N N . ILE A 1 69 ? 125.451 564.258 82.320 1.00 23.21 ? 101 ILE A N 1 ATOM 544 C CA . ILE A 1 69 ? 124.482 565.135 82.979 1.00 22.67 ? 101 ILE A CA 1 ATOM 545 C C . ILE A 1 69 ? 123.543 564.285 83.809 1.00 28.28 ? 101 ILE A C 1 ATOM 546 O O . ILE A 1 69 ? 122.803 563.455 83.281 1.00 28.87 ? 101 ILE A O 1 ATOM 547 C CB . ILE A 1 69 ? 123.681 566.010 81.954 1.00 24.55 ? 101 ILE A CB 1 ATOM 548 C CG1 . ILE A 1 69 ? 124.587 566.951 81.188 1.00 23.74 ? 101 ILE A CG1 1 ATOM 549 C CG2 . ILE A 1 69 ? 122.527 566.771 82.617 1.00 22.21 ? 101 ILE A CG2 1 ATOM 550 C CD1 . ILE A 1 69 ? 124.052 567.264 79.814 1.00 28.14 ? 101 ILE A CD1 1 ATOM 551 N N . ARG A 1 70 ? 123.572 564.495 85.107 1.00 24.89 ? 102 ARG A N 1 ATOM 552 C CA . ARG A 1 70 ? 122.662 563.816 85.986 1.00 23.67 ? 102 ARG A CA 1 ATOM 553 C C . ARG A 1 70 ? 121.856 564.834 86.762 1.00 25.56 ? 102 ARG A C 1 ATOM 554 O O . ARG A 1 70 ? 122.410 565.828 87.232 1.00 24.97 ? 102 ARG A O 1 ATOM 555 C CB . ARG A 1 70 ? 123.394 562.847 86.891 1.00 22.42 ? 102 ARG A CB 1 ATOM 556 C CG . ARG A 1 70 ? 123.736 561.573 86.186 1.00 30.95 ? 102 ARG A CG 1 ATOM 557 C CD . ARG A 1 70 ? 124.406 560.585 87.105 1.00 31.40 ? 102 ARG A CD 1 ATOM 558 N NE . ARG A 1 70 ? 125.781 560.968 87.436 1.00 30.12 ? 102 ARG A NE 1 ATOM 559 C CZ . ARG A 1 70 ? 126.584 560.236 88.203 1.00 29.22 ? 102 ARG A CZ 1 ATOM 560 N NH1 . ARG A 1 70 ? 126.161 559.100 88.722 1.00 21.97 ? 102 ARG A NH1 1 ATOM 561 N NH2 . ARG A 1 70 ? 127.815 560.635 88.448 1.00 20.50 ? 102 ARG A NH2 1 ATOM 562 N N . ILE A 1 71 ? 120.535 564.625 86.816 1.00 21.28 ? 103 ILE A N 1 ATOM 563 C CA . ILE A 1 71 ? 119.623 565.492 87.559 1.00 21.01 ? 103 ILE A CA 1 ATOM 564 C C . ILE A 1 71 ? 118.759 564.610 88.449 1.00 26.43 ? 103 ILE A C 1 ATOM 565 O O . ILE A 1 71 ? 118.191 563.621 87.985 1.00 26.55 ? 103 ILE A O 1 ATOM 566 C CB . ILE A 1 71 ? 118.791 566.445 86.642 1.00 22.85 ? 103 ILE A CB 1 ATOM 567 C CG1 . ILE A 1 71 ? 119.697 567.240 85.680 1.00 21.28 ? 103 ILE A CG1 1 ATOM 568 C CG2 . ILE A 1 71 ? 117.907 567.374 87.479 1.00 21.97 ? 103 ILE A CG2 1 ATOM 569 C CD1 . ILE A 1 71 ? 118.995 567.999 84.632 1.00 24.44 ? 103 ILE A CD1 1 ATOM 570 N N . ASP A 1 72 ? 118.708 564.942 89.740 1.00 24.99 ? 104 ASP A N 1 ATOM 571 C CA . ASP A 1 72 ? 117.888 564.247 90.741 1.00 25.50 ? 104 ASP A CA 1 ATOM 572 C C . ASP A 1 72 ? 117.297 565.293 91.662 1.00 30.06 ? 104 ASP A C 1 ATOM 573 O O . ASP A 1 72 ? 117.731 566.440 91.629 1.00 27.84 ? 104 ASP A O 1 ATOM 574 C CB . ASP A 1 72 ? 118.758 563.264 91.564 1.00 27.80 ? 104 ASP A CB 1 ATOM 575 C CG . ASP A 1 72 ? 118.020 562.200 92.362 1.00 35.46 ? 104 ASP A CG 1 ATOM 576 O OD1 . ASP A 1 72 ? 116.763 562.205 92.356 1.00 37.19 ? 104 ASP A OD1 1 ATOM 577 O OD2 . ASP A 1 72 ? 118.698 561.335 92.963 1.00 37.61 ? 104 ASP A OD2 1 ATOM 578 N N . GLU A 1 73 ? 116.309 564.911 92.475 1.00 29.25 ? 105 GLU A N 1 ATOM 579 C CA . GLU A 1 73 ? 115.714 565.794 93.484 1.00 29.79 ? 105 GLU A CA 1 ATOM 580 C C . GLU A 1 73 ? 116.746 566.064 94.588 1.00 36.21 ? 105 GLU A C 1 ATOM 581 O O . GLU A 1 73 ? 117.491 565.161 94.958 1.00 36.00 ? 105 GLU A O 1 ATOM 582 C CB . GLU A 1 73 ? 114.478 565.146 94.110 1.00 31.01 ? 105 GLU A CB 1 ATOM 583 C CG . GLU A 1 73 ? 113.330 564.991 93.151 1.00 35.54 ? 105 GLU A CG 1 ATOM 584 C CD . GLU A 1 73 ? 112.072 564.443 93.784 1.00 51.10 ? 105 GLU A CD 1 ATOM 585 O OE1 . GLU A 1 73 ? 111.638 564.981 94.827 1.00 49.34 ? 105 GLU A OE1 1 ATOM 586 O OE2 . GLU A 1 73 ? 111.507 563.477 93.227 1.00 44.30 ? 105 GLU A OE2 1 ATOM 587 N N . LEU A 1 74 ? 116.813 567.305 95.095 1.00 34.31 ? 106 LEU A N 1 ATOM 588 C CA . LEU A 1 74 ? 117.717 567.637 96.190 1.00 34.50 ? 106 LEU A CA 1 ATOM 589 C C . LEU A 1 74 ? 117.283 566.924 97.484 1.00 45.75 ? 106 LEU A C 1 ATOM 590 O O . LEU A 1 74 ? 118.135 566.386 98.207 1.00 46.33 ? 106 LEU A O 1 ATOM 591 C CB . LEU A 1 74 ? 117.738 569.149 96.424 1.00 33.89 ? 106 LEU A CB 1 ATOM 592 C CG . LEU A 1 74 ? 118.552 569.694 97.617 1.00 36.51 ? 106 LEU A CG 1 ATOM 593 C CD1 . LEU A 1 74 ? 120.047 569.341 97.520 1.00 35.07 ? 106 LEU A CD1 1 ATOM 594 C CD2 . LEU A 1 74 ? 118.375 571.192 97.740 1.00 37.21 ? 106 LEU A CD2 1 ATOM 595 N N . GLU A 1 75 ? 115.964 566.934 97.781 1.00 45.41 ? 107 GLU A N 1 ATOM 596 C CA . GLU A 1 75 ? 115.445 566.347 99.020 1.00 45.77 ? 107 GLU A CA 1 ATOM 597 C C . GLU A 1 75 ? 114.303 565.392 98.645 1.00 46.48 ? 107 GLU A C 1 ATOM 598 O O . GLU A 1 75 ? 113.124 565.768 98.716 1.00 45.50 ? 107 GLU A O 1 ATOM 599 C CB . GLU A 1 75 ? 114.960 567.459 99.990 1.00 47.68 ? 107 GLU A CB 1 ATOM 600 C CG . GLU A 1 75 ? 115.911 568.629 100.257 1.00 58.92 ? 107 GLU A CG 1 ATOM 601 C CD . GLU A 1 75 ? 115.237 569.857 100.851 1.00 84.21 ? 107 GLU A CD 1 ATOM 602 O OE1 . GLU A 1 75 ? 115.467 570.978 100.335 1.00 84.03 ? 107 GLU A OE1 1 ATOM 603 O OE2 . GLU A 1 75 ? 114.457 569.692 101.819 1.00 76.52 ? 107 GLU A OE2 1 ATOM 604 N N . PRO A 1 76 ? 114.617 564.169 98.169 1.00 40.03 ? 108 PRO A N 1 ATOM 605 C CA . PRO A 1 76 ? 113.527 563.281 97.766 1.00 38.74 ? 108 PRO A CA 1 ATOM 606 C C . PRO A 1 76 ? 112.832 562.640 98.946 1.00 43.81 ? 108 PRO A C 1 ATOM 607 O O . PRO A 1 76 ? 113.461 562.374 99.976 1.00 43.48 ? 108 PRO A O 1 ATOM 608 C CB . PRO A 1 76 ? 114.218 562.235 96.903 1.00 39.95 ? 108 PRO A CB 1 ATOM 609 C CG . PRO A 1 76 ? 115.629 562.216 97.379 1.00 44.20 ? 108 PRO A CG 1 ATOM 610 C CD . PRO A 1 76 ? 115.941 563.532 98.001 1.00 40.17 ? 108 PRO A CD 1 ATOM 611 N N . ARG A 1 77 ? 111.531 562.364 98.775 1.00 41.48 ? 109 ARG A N 1 ATOM 612 C CA . ARG A 1 77 ? 110.707 561.607 99.730 1.00 41.68 ? 109 ARG A CA 1 ATOM 613 C C . ARG A 1 77 ? 111.216 560.171 99.824 1.00 44.48 ? 109 ARG A C 1 ATOM 614 O O . ARG A 1 77 ? 111.254 559.603 100.915 1.00 44.75 ? 109 ARG A O 1 ATOM 615 C CB . ARG A 1 77 ? 109.239 561.581 99.292 1.00 42.47 ? 109 ARG A CB 1 ATOM 616 C CG . ARG A 1 77 ? 108.578 562.905 99.547 1.00 56.02 ? 109 ARG A CG 1 ATOM 617 C CD . ARG A 1 77 ? 107.166 562.957 99.042 1.00 71.89 ? 109 ARG A CD 1 ATOM 618 N NE . ARG A 1 77 ? 106.499 564.141 99.578 1.00 85.45 ? 109 ARG A NE 1 ATOM 619 C CZ . ARG A 1 77 ? 105.881 564.174 100.754 1.00 104.55 ? 109 ARG A CZ 1 ATOM 620 N NH1 . ARG A 1 77 ? 105.799 563.077 101.501 1.00 92.82 ? 109 ARG A NH1 1 ATOM 621 N NH2 . ARG A 1 77 ? 105.320 565.296 101.185 1.00 93.25 ? 109 ARG A NH2 1 ATOM 622 N N . ARG A 1 78 ? 111.608 559.598 98.678 1.00 39.30 ? 110 ARG A N 1 ATOM 623 C CA . ARG A 1 78 ? 112.132 558.247 98.551 1.00 37.51 ? 110 ARG A CA 1 ATOM 624 C C . ARG A 1 78 ? 113.219 558.237 97.472 1.00 37.79 ? 110 ARG A C 1 ATOM 625 O O . ARG A 1 78 ? 113.149 559.035 96.543 1.00 37.02 ? 110 ARG A O 1 ATOM 626 C CB . ARG A 1 78 ? 110.978 557.191 98.373 1.00 37.35 ? 110 ARG A CB 1 ATOM 627 C CG . ARG A 1 78 ? 110.668 556.606 96.970 1.00 50.29 ? 110 ARG A CG 1 ATOM 628 C CD . ARG A 1 78 ? 110.472 555.054 96.908 1.00 68.71 ? 110 ARG A CD 1 ATOM 629 N NE . ARG A 1 78 ? 111.703 554.259 97.124 1.00 75.07 ? 110 ARG A NE 1 ATOM 630 C CZ . ARG A 1 78 ? 111.875 552.975 96.782 1.00 77.41 ? 110 ARG A CZ 1 ATOM 631 N NH1 . ARG A 1 78 ? 110.902 552.304 96.178 1.00 66.32 ? 110 ARG A NH1 1 ATOM 632 N NH2 . ARG A 1 78 ? 113.031 552.365 97.024 1.00 47.12 ? 110 ARG A NH2 1 ATOM 633 N N . PRO A 1 79 ? 114.270 557.406 97.577 1.00 34.20 ? 111 PRO A N 1 ATOM 634 C CA . PRO A 1 79 ? 115.285 557.426 96.503 1.00 33.77 ? 111 PRO A CA 1 ATOM 635 C C . PRO A 1 79 ? 114.718 557.092 95.102 1.00 35.01 ? 111 PRO A C 1 ATOM 636 O O . PRO A 1 79 ? 113.808 556.275 94.979 1.00 33.54 ? 111 PRO A O 1 ATOM 637 C CB . PRO A 1 79 ? 116.346 556.412 96.953 1.00 35.63 ? 111 PRO A CB 1 ATOM 638 C CG . PRO A 1 79 ? 115.890 555.858 98.251 1.00 39.87 ? 111 PRO A CG 1 ATOM 639 C CD . PRO A 1 79 ? 114.569 556.412 98.635 1.00 35.07 ? 111 PRO A CD 1 ATOM 640 N N . ARG A 1 80 ? 115.244 557.771 94.062 1.00 29.81 ? 112 ARG A N 1 ATOM 641 C CA . ARG A 1 80 ? 114.946 557.527 92.654 1.00 28.72 ? 112 ARG A CA 1 ATOM 642 C C . ARG A 1 80 ? 115.920 556.487 92.091 1.00 32.31 ? 112 ARG A C 1 ATOM 643 O O . ARG A 1 80 ? 117.112 556.481 92.418 1.00 32.70 ? 112 ARG A O 1 ATOM 644 C CB . ARG A 1 80 ? 115.109 558.808 91.835 1.00 29.31 ? 112 ARG A CB 1 ATOM 645 C CG . ARG A 1 80 ? 113.971 559.778 92.005 1.00 38.62 ? 112 ARG A CG 1 ATOM 646 C CD . ARG A 1 80 ? 113.969 560.885 90.977 1.00 41.59 ? 112 ARG A CD 1 ATOM 647 N NE . ARG A 1 80 ? 112.734 561.619 91.145 1.00 43.69 ? 112 ARG A NE 1 ATOM 648 C CZ . ARG A 1 80 ? 111.683 561.563 90.338 1.00 55.08 ? 112 ARG A CZ 1 ATOM 649 N NH1 . ARG A 1 80 ? 111.744 560.885 89.193 1.00 41.16 ? 112 ARG A NH1 1 ATOM 650 N NH2 . ARG A 1 80 ? 110.585 562.233 90.636 1.00 29.28 ? 112 ARG A NH2 1 ATOM 651 N N . TYR A 1 81 ? 115.416 555.632 91.208 1.00 27.06 ? 113 TYR A N 1 ATOM 652 C CA . TYR A 1 81 ? 116.215 554.598 90.583 1.00 24.14 ? 113 TYR A CA 1 ATOM 653 C C . TYR A 1 81 ? 117.354 555.165 89.736 1.00 26.18 ? 113 TYR A C 1 ATOM 654 O O . TYR A 1 81 ? 117.198 556.160 89.036 1.00 24.47 ? 113 TYR A O 1 ATOM 655 C CB . TYR A 1 81 ? 115.316 553.737 89.699 1.00 22.53 ? 113 TYR A CB 1 ATOM 656 C CG . TYR A 1 81 ? 115.922 552.403 89.332 1.00 20.74 ? 113 TYR A CG 1 ATOM 657 C CD1 . TYR A 1 81 ? 116.088 551.408 90.288 1.00 22.25 ? 113 TYR A CD1 1 ATOM 658 C CD2 . TYR A 1 81 ? 116.307 552.123 88.020 1.00 20.51 ? 113 TYR A CD2 1 ATOM 659 C CE1 . TYR A 1 81 ? 116.580 550.151 89.947 1.00 21.87 ? 113 TYR A CE1 1 ATOM 660 C CE2 . TYR A 1 81 ? 116.826 550.876 87.673 1.00 21.48 ? 113 TYR A CE2 1 ATOM 661 C CZ . TYR A 1 81 ? 116.956 549.896 88.644 1.00 27.82 ? 113 TYR A CZ 1 ATOM 662 O OH . TYR A 1 81 ? 117.398 548.649 88.346 1.00 29.97 ? 113 TYR A OH 1 ATOM 663 N N . ARG A 1 82 ? 118.504 554.512 89.810 1.00 23.32 ? 114 ARG A N 1 ATOM 664 C CA . ARG A 1 82 ? 119.681 554.775 88.980 1.00 21.83 ? 114 ARG A CA 1 ATOM 665 C C . ARG A 1 82 ? 120.041 553.419 88.423 1.00 21.82 ? 114 ARG A C 1 ATOM 666 O O . ARG A 1 82 ? 120.088 552.461 89.178 1.00 17.58 ? 114 ARG A O 1 ATOM 667 C CB . ARG A 1 82 ? 120.825 555.366 89.795 1.00 22.11 ? 114 ARG A CB 1 ATOM 668 C CG . ARG A 1 82 ? 120.538 556.787 90.260 1.00 23.70 ? 114 ARG A CG 1 ATOM 669 C CD . ARG A 1 82 ? 121.544 557.266 91.293 1.00 19.20 ? 114 ARG A CD 1 ATOM 670 N NE . ARG A 1 82 ? 121.190 558.587 91.815 1.00 30.93 ? 114 ARG A NE 1 ATOM 671 C CZ . ARG A 1 82 ? 121.876 559.709 91.593 1.00 37.64 ? 114 ARG A CZ 1 ATOM 672 N NH1 . ARG A 1 82 ? 122.976 559.686 90.854 1.00 17.49 ? 114 ARG A NH1 1 ATOM 673 N NH2 . ARG A 1 82 ? 121.468 560.861 92.119 1.00 19.41 ? 114 ARG A NH2 1 ATOM 674 N N . VAL A 1 83 ? 120.203 553.311 87.094 1.00 20.05 ? 115 VAL A N 1 ATOM 675 C CA . VAL A 1 83 ? 120.363 552.008 86.457 1.00 18.77 ? 115 VAL A CA 1 ATOM 676 C C . VAL A 1 83 ? 121.625 551.306 86.828 1.00 23.73 ? 115 VAL A C 1 ATOM 677 O O . VAL A 1 83 ? 122.697 551.773 86.487 1.00 24.46 ? 115 VAL A O 1 ATOM 678 C CB . VAL A 1 83 ? 120.203 552.036 84.930 1.00 21.49 ? 115 VAL A CB 1 ATOM 679 C CG1 . VAL A 1 83 ? 120.099 550.626 84.364 1.00 20.60 ? 115 VAL A CG1 1 ATOM 680 C CG2 . VAL A 1 83 ? 118.978 552.829 84.534 1.00 21.30 ? 115 VAL A CG2 1 ATOM 681 N N . PRO A 1 84 ? 121.514 550.130 87.453 1.00 20.97 ? 116 PRO A N 1 ATOM 682 C CA . PRO A 1 84 ? 122.726 549.363 87.793 1.00 21.92 ? 116 PRO A CA 1 ATOM 683 C C . PRO A 1 84 ? 123.132 548.373 86.700 1.00 25.78 ? 116 PRO A C 1 ATOM 684 O O . PRO A 1 84 ? 122.328 548.051 85.818 1.00 26.21 ? 116 PRO A O 1 ATOM 685 C CB . PRO A 1 84 ? 122.278 548.564 89.027 1.00 23.75 ? 116 PRO A CB 1 ATOM 686 C CG . PRO A 1 84 ? 120.826 548.277 88.750 1.00 27.95 ? 116 PRO A CG 1 ATOM 687 C CD . PRO A 1 84 ? 120.293 549.453 87.927 1.00 22.51 ? 116 PRO A CD 1 ATOM 688 N N . ASP A 1 85 ? 124.365 547.872 86.778 1.00 21.83 ? 117 ASP A N 1 ATOM 689 C CA . ASP A 1 85 ? 124.897 546.760 85.991 1.00 22.16 ? 117 ASP A CA 1 ATOM 690 C C . ASP A 1 85 ? 124.991 546.957 84.487 1.00 26.08 ? 117 ASP A C 1 ATOM 691 O O . ASP A 1 85 ? 125.343 546.007 83.777 1.00 25.01 ? 117 ASP A O 1 ATOM 692 C CB . ASP A 1 85 ? 124.074 545.474 86.290 1.00 24.36 ? 117 ASP A CB 1 ATOM 693 C CG . ASP A 1 85 ? 124.179 545.046 87.750 1.00 27.33 ? 117 ASP A CG 1 ATOM 694 O OD1 . ASP A 1 85 ? 125.306 544.805 88.211 1.00 26.94 ? 117 ASP A OD1 1 ATOM 695 O OD2 . ASP A 1 85 ? 123.135 545.009 88.442 1.00 25.24 ? 117 ASP A OD2 1 ATOM 696 N N . VAL A 1 86 ? 124.700 548.154 83.993 1.00 22.27 ? 118 VAL A N 1 ATOM 697 C CA . VAL A 1 86 ? 124.776 548.426 82.559 1.00 22.16 ? 118 VAL A CA 1 ATOM 698 C C . VAL A 1 86 ? 126.156 548.962 82.257 1.00 24.58 ? 118 VAL A C 1 ATOM 699 O O . VAL A 1 86 ? 126.830 548.433 81.374 1.00 23.31 ? 118 VAL A O 1 ATOM 700 C CB . VAL A 1 86 ? 123.645 549.354 82.095 1.00 26.43 ? 118 VAL A CB 1 ATOM 701 C CG1 . VAL A 1 86 ? 123.897 549.863 80.691 1.00 25.77 ? 118 VAL A CG1 1 ATOM 702 C CG2 . VAL A 1 86 ? 122.308 548.634 82.181 1.00 26.91 ? 118 VAL A CG2 1 ATOM 703 N N . LEU A 1 87 ? 126.591 549.965 83.029 1.00 20.61 ? 119 LEU A N 1 ATOM 704 C CA . LEU A 1 87 ? 127.935 550.524 82.937 1.00 20.39 ? 119 LEU A CA 1 ATOM 705 C C . LEU A 1 87 ? 128.961 549.482 83.400 1.00 26.12 ? 119 LEU A C 1 ATOM 706 O O . LEU A 1 87 ? 128.762 548.864 84.446 1.00 26.17 ? 119 LEU A O 1 ATOM 707 C CB . LEU A 1 87 ? 128.052 551.808 83.791 1.00 19.38 ? 119 LEU A CB 1 ATOM 708 C CG . LEU A 1 87 ? 127.146 552.973 83.390 1.00 23.42 ? 119 LEU A CG 1 ATOM 709 C CD1 . LEU A 1 87 ? 127.438 554.188 84.246 1.00 23.47 ? 119 LEU A CD1 1 ATOM 710 C CD2 . LEU A 1 87 ? 127.316 553.346 81.913 1.00 23.98 ? 119 LEU A CD2 1 ATOM 711 N N . VAL A 1 88 ? 130.028 549.278 82.615 1.00 24.24 ? 120 VAL A N 1 ATOM 712 C CA . VAL A 1 88 ? 131.105 548.315 82.922 1.00 24.26 ? 120 VAL A CA 1 ATOM 713 C C . VAL A 1 88 ? 132.137 548.839 83.901 1.00 27.88 ? 120 VAL A C 1 ATOM 714 O O . VAL A 1 88 ? 132.900 548.065 84.493 1.00 27.58 ? 120 VAL A O 1 ATOM 715 C CB . VAL A 1 88 ? 131.789 547.736 81.679 1.00 28.02 ? 120 VAL A CB 1 ATOM 716 C CG1 . VAL A 1 88 ? 130.804 546.913 80.873 1.00 28.01 ? 120 VAL A CG1 1 ATOM 717 C CG2 . VAL A 1 88 ? 132.429 548.804 80.807 1.00 27.97 ? 120 VAL A CG2 1 ATOM 718 N N . ALA A 1 89 ? 132.188 550.156 84.041 1.00 24.84 ? 121 ALA A N 1 ATOM 719 C CA . ALA A 1 89 ? 133.134 550.832 84.901 1.00 24.81 ? 121 ALA A CA 1 ATOM 720 C C . ALA A 1 89 ? 132.584 552.197 85.241 1.00 31.09 ? 121 ALA A C 1 ATOM 721 O O . ALA A 1 89 ? 131.636 552.685 84.615 1.00 28.71 ? 121 ALA A O 1 ATOM 722 C CB . ALA A 1 89 ? 134.483 550.981 84.189 1.00 25.28 ? 121 ALA A CB 1 ATOM 723 N N . ASP A 1 90 ? 133.167 552.791 86.280 1.00 31.05 ? 122 ASP A N 1 ATOM 724 C CA . ASP A 1 90 ? 132.862 554.140 86.669 1.00 31.23 ? 122 ASP A CA 1 ATOM 725 C C . ASP A 1 90 ? 133.653 554.977 85.660 1.00 37.06 ? 122 ASP A C 1 ATOM 726 O O . ASP A 1 90 ? 134.884 554.868 85.576 1.00 38.81 ? 122 ASP A O 1 ATOM 727 C CB . ASP A 1 90 ? 133.321 554.405 88.086 1.00 32.74 ? 122 ASP A CB 1 ATOM 728 C CG . ASP A 1 90 ? 132.738 555.660 88.669 1.00 45.55 ? 122 ASP A CG 1 ATOM 729 O OD1 . ASP A 1 90 ? 131.969 556.359 87.955 1.00 47.12 ? 122 ASP A OD1 1 ATOM 730 O OD2 . ASP A 1 90 ? 133.023 555.943 89.838 1.00 52.68 ? 122 ASP A OD2 1 ATOM 731 N N . PRO A 1 91 ? 132.960 555.721 84.790 1.00 33.02 ? 123 PRO A N 1 ATOM 732 C CA . PRO A 1 91 ? 133.678 556.432 83.724 1.00 32.12 ? 123 PRO A CA 1 ATOM 733 C C . PRO A 1 91 ? 134.779 557.364 84.215 1.00 34.22 ? 123 PRO A C 1 ATOM 734 O O . PRO A 1 91 ? 134.527 558.194 85.111 1.00 32.88 ? 123 PRO A O 1 ATOM 735 C CB . PRO A 1 91 ? 132.568 557.193 82.999 1.00 33.76 ? 123 PRO A CB 1 ATOM 736 C CG . PRO A 1 91 ? 131.334 556.400 83.308 1.00 38.24 ? 123 PRO A CG 1 ATOM 737 C CD . PRO A 1 91 ? 131.500 555.931 84.695 1.00 33.68 ? 123 PRO A CD 1 ATOM 738 N N . PRO A 1 92 ? 136.010 557.226 83.664 1.00 29.04 ? 124 PRO A N 1 ATOM 739 C CA . PRO A 1 92 ? 137.088 558.152 84.052 1.00 28.54 ? 124 PRO A CA 1 ATOM 740 C C . PRO A 1 92 ? 136.716 559.595 83.702 1.00 32.18 ? 124 PRO A C 1 ATOM 741 O O . PRO A 1 92 ? 136.279 559.877 82.584 1.00 33.51 ? 124 PRO A O 1 ATOM 742 C CB . PRO A 1 92 ? 138.283 557.666 83.234 1.00 30.04 ? 124 PRO A CB 1 ATOM 743 C CG . PRO A 1 92 ? 137.954 556.245 82.893 1.00 33.97 ? 124 PRO A CG 1 ATOM 744 C CD . PRO A 1 92 ? 136.480 556.255 82.657 1.00 29.31 ? 124 PRO A CD 1 ATOM 745 N N . THR A 1 93 ? 136.868 560.506 84.659 1.00 27.86 ? 125 THR A N 1 ATOM 746 C CA . THR A 1 93 ? 136.483 561.908 84.479 1.00 26.87 ? 125 THR A CA 1 ATOM 747 C C . THR A 1 93 ? 137.569 562.800 83.910 1.00 31.36 ? 125 THR A C 1 ATOM 748 O O . THR A 1 93 ? 138.732 562.408 83.808 1.00 29.88 ? 125 THR A O 1 ATOM 749 C CB . THR A 1 93 ? 135.966 562.494 85.801 1.00 26.67 ? 125 THR A CB 1 ATOM 750 O OG1 . THR A 1 93 ? 137.032 562.506 86.735 1.00 28.07 ? 125 THR A OG1 1 ATOM 751 C CG2 . THR A 1 93 ? 134.811 561.708 86.372 1.00 19.65 ? 125 THR A CG2 1 ATOM 752 N N . ALA A 1 94 ? 137.153 564.017 83.518 1.00 29.90 ? 126 ALA A N 1 ATOM 753 C CA . ALA A 1 94 ? 138.011 565.114 83.084 1.00 29.41 ? 126 ALA A CA 1 ATOM 754 C C . ALA A 1 94 ? 137.555 566.361 83.836 1.00 34.28 ? 126 ALA A C 1 ATOM 755 O O . ALA A 1 94 ? 136.346 566.602 84.001 1.00 32.99 ? 126 ALA A O 1 ATOM 756 C CB . ALA A 1 94 ? 137.934 565.323 81.586 1.00 30.17 ? 126 ALA A CB 1 ATOM 757 N N . ARG A 1 95 ? 138.546 567.135 84.310 1.00 33.69 ? 127 ARG A N 1 ATOM 758 C CA . ARG A 1 95 ? 138.338 568.326 85.119 1.00 34.47 ? 127 ARG A CA 1 ATOM 759 C C . ARG A 1 95 ? 137.662 569.453 84.373 1.00 36.14 ? 127 ARG A C 1 ATOM 760 O O . ARG A 1 95 ? 138.065 569.781 83.269 1.00 35.14 ? 127 ARG A O 1 ATOM 761 C CB . ARG A 1 95 ? 139.660 568.818 85.732 1.00 36.98 ? 127 ARG A CB 1 ATOM 762 C CG . ARG A 1 95 ? 139.454 570.035 86.641 1.00 58.50 ? 127 ARG A CG 1 ATOM 763 C CD . ARG A 1 95 ? 140.718 570.754 87.067 1.00 80.65 ? 127 ARG A CD 1 ATOM 764 N NE . ARG A 1 95 ? 141.460 570.029 88.105 1.00 98.13 ? 127 ARG A NE 1 ATOM 765 C CZ . ARG A 1 95 ? 141.125 569.973 89.394 1.00 110.75 ? 127 ARG A CZ 1 ATOM 766 N NH1 . ARG A 1 95 ? 140.020 570.574 89.831 1.00 98.09 ? 127 ARG A NH1 1 ATOM 767 N NH2 . ARG A 1 95 ? 141.877 569.291 90.252 1.00 91.46 ? 127 ARG A NH2 1 ATOM 768 N N . LEU A 1 96 ? 136.670 570.069 85.008 1.00 30.60 ? 128 LEU A N 1 ATOM 769 C CA . LEU A 1 96 ? 136.026 571.239 84.464 1.00 30.45 ? 128 LEU A CA 1 ATOM 770 C C . LEU A 1 96 ? 136.646 572.442 85.177 1.00 36.37 ? 128 LEU A C 1 ATOM 771 O O . LEU A 1 96 ? 136.782 572.416 86.403 1.00 36.82 ? 128 LEU A O 1 ATOM 772 C CB . LEU A 1 96 ? 134.525 571.178 84.742 1.00 30.16 ? 128 LEU A CB 1 ATOM 773 C CG . LEU A 1 96 ? 133.765 570.038 84.100 1.00 32.03 ? 128 LEU A CG 1 ATOM 774 C CD1 . LEU A 1 96 ? 132.376 570.001 84.623 1.00 30.17 ? 128 LEU A CD1 1 ATOM 775 C CD2 . LEU A 1 96 ? 133.771 570.169 82.593 1.00 28.87 ? 128 LEU A CD2 1 ATOM 776 N N . SER A 1 97 ? 137.065 573.470 84.413 1.00 33.22 ? 129 SER A N 1 ATOM 777 C CA . SER A 1 97 ? 137.659 574.722 84.916 1.00 32.53 ? 129 SER A CA 1 ATOM 778 C C . SER A 1 97 ? 136.797 575.895 84.522 1.00 38.04 ? 129 SER A C 1 ATOM 779 O O . SER A 1 97 ? 136.408 575.990 83.355 1.00 38.22 ? 129 SER A O 1 ATOM 780 C CB . SER A 1 97 ? 139.024 574.959 84.280 1.00 34.22 ? 129 SER A CB 1 ATOM 781 O OG . SER A 1 97 ? 139.965 573.992 84.693 1.00 47.46 ? 129 SER A OG 1 ATOM 782 N N . VAL A 1 98 ? 136.586 576.851 85.422 1.00 35.97 ? 130 VAL A N 1 ATOM 783 C CA . VAL A 1 98 ? 135.828 578.049 85.036 1.00 35.79 ? 130 VAL A CA 1 ATOM 784 C C . VAL A 1 98 ? 136.695 578.976 84.166 1.00 42.90 ? 130 VAL A C 1 ATOM 785 O O . VAL A 1 98 ? 137.693 579.503 84.657 1.00 44.12 ? 130 VAL A O 1 ATOM 786 C CB . VAL A 1 98 ? 135.256 578.790 86.248 1.00 38.18 ? 130 VAL A CB 1 ATOM 787 C CG1 . VAL A 1 98 ? 134.467 580.029 85.804 1.00 37.90 ? 130 VAL A CG1 1 ATOM 788 C CG2 . VAL A 1 98 ? 134.405 577.856 87.093 1.00 37.41 ? 130 VAL A CG2 1 ATOM 789 N N . SER A 1 99 ? 136.336 579.156 82.881 1.00 40.30 ? 131 SER A N 1 ATOM 790 C CA . SER A 1 99 ? 137.067 580.063 81.981 1.00 40.84 ? 131 SER A CA 1 ATOM 791 C C . SER A 1 99 ? 136.291 581.354 81.655 1.00 45.44 ? 131 SER A C 1 ATOM 792 O O . SER A 1 99 ? 136.736 582.150 80.822 1.00 45.91 ? 131 SER A O 1 ATOM 793 C CB . SER A 1 99 ? 137.438 579.343 80.689 1.00 45.16 ? 131 SER A CB 1 ATOM 794 O OG . SER A 1 99 ? 136.310 578.665 80.164 1.00 51.98 ? 131 SER A OG 1 ATOM 795 N N . GLY A 1 100 ? 135.143 581.537 82.297 1.00 41.83 ? 132 GLY A N 1 ATOM 796 C CA . GLY A 1 100 ? 134.245 582.658 82.051 1.00 41.39 ? 132 GLY A CA 1 ATOM 797 C C . GLY A 1 100 ? 133.063 582.615 82.985 1.00 44.64 ? 132 GLY A C 1 ATOM 798 O O . GLY A 1 100 ? 132.552 581.540 83.308 1.00 43.59 ? 132 GLY A O 1 ATOM 799 N N . ARG A 1 101 ? 132.644 583.776 83.449 1.00 42.32 ? 133 ARG A N 1 ATOM 800 C CA . ARG A 1 101 ? 131.577 583.828 84.427 1.00 42.72 ? 133 ARG A CA 1 ATOM 801 C C . ARG A 1 101 ? 130.946 585.199 84.465 1.00 48.62 ? 133 ARG A C 1 ATOM 802 O O . ARG A 1 101 ? 131.662 586.200 84.417 1.00 50.39 ? 133 ARG A O 1 ATOM 803 C CB . ARG A 1 101 ? 132.165 583.512 85.825 1.00 41.72 ? 133 ARG A CB 1 ATOM 804 C CG . ARG A 1 101 ? 131.201 582.859 86.797 1.00 44.27 ? 133 ARG A CG 1 ATOM 805 C CD . ARG A 1 101 ? 131.764 582.925 88.195 1.00 47.00 ? 133 ARG A CD 1 ATOM 806 N NE . ARG A 1 101 ? 131.228 581.932 89.133 1.00 58.90 ? 133 ARG A NE 1 ATOM 807 C CZ . ARG A 1 101 ? 129.975 581.884 89.584 1.00 68.12 ? 133 ARG A CZ 1 ATOM 808 N NH1 . ARG A 1 101 ? 129.053 582.717 89.105 1.00 58.23 ? 133 ARG A NH1 1 ATOM 809 N NH2 . ARG A 1 101 ? 129.627 580.980 90.491 1.00 44.76 ? 133 ARG A NH2 1 ATOM 810 N N . ASP A 1 102 ? 129.606 585.245 84.565 1.00 43.76 ? 134 ASP A N 1 ATOM 811 C CA . ASP A 1 102 ? 128.836 586.451 84.833 1.00 42.75 ? 134 ASP A CA 1 ATOM 812 C C . ASP A 1 102 ? 127.638 586.101 85.715 1.00 46.95 ? 134 ASP A C 1 ATOM 813 O O . ASP A 1 102 ? 127.545 584.964 86.215 1.00 46.42 ? 134 ASP A O 1 ATOM 814 C CB . ASP A 1 102 ? 128.479 587.267 83.576 1.00 44.44 ? 134 ASP A CB 1 ATOM 815 C CG . ASP A 1 102 ? 127.572 586.601 82.569 1.00 53.54 ? 134 ASP A CG 1 ATOM 816 O OD1 . ASP A 1 102 ? 126.763 585.750 82.971 1.00 56.91 ? 134 ASP A OD1 1 ATOM 817 O OD2 . ASP A 1 102 ? 127.637 586.970 81.381 1.00 53.76 ? 134 ASP A OD2 1 ATOM 818 N N . ASP A 1 103 ? 126.731 587.068 85.915 1.00 43.98 ? 135 ASP A N 1 ATOM 819 C CA . ASP A 1 103 ? 125.525 586.891 86.728 1.00 44.27 ? 135 ASP A CA 1 ATOM 820 C C . ASP A 1 103 ? 124.606 585.788 86.191 1.00 44.17 ? 135 ASP A C 1 ATOM 821 O O . ASP A 1 103 ? 123.859 585.201 86.982 1.00 43.38 ? 135 ASP A O 1 ATOM 822 C CB . ASP A 1 103 ? 124.730 588.210 86.829 1.00 47.53 ? 135 ASP A CB 1 ATOM 823 C CG . ASP A 1 103 ? 125.428 589.301 87.619 1.00 68.53 ? 135 ASP A CG 1 ATOM 824 O OD1 . ASP A 1 103 ? 125.387 589.248 88.877 1.00 70.84 ? 135 ASP A OD1 1 ATOM 825 O OD2 . ASP A 1 103 ? 126.007 590.215 86.985 1.00 75.89 ? 135 ASP A OD2 1 ATOM 826 N N . ASN A 1 104 ? 124.618 585.520 84.866 1.00 36.79 ? 136 ASN A N 1 ATOM 827 C CA . ASN A 1 104 ? 123.690 584.509 84.358 1.00 36.22 ? 136 ASN A CA 1 ATOM 828 C C . ASN A 1 104 ? 124.307 583.320 83.629 1.00 42.58 ? 136 ASN A C 1 ATOM 829 O O . ASN A 1 104 ? 123.574 582.487 83.087 1.00 44.24 ? 136 ASN A O 1 ATOM 830 C CB . ASN A 1 104 ? 122.665 585.172 83.446 1.00 33.23 ? 136 ASN A CB 1 ATOM 831 C CG . ASN A 1 104 ? 121.461 584.307 83.175 1.00 46.00 ? 136 ASN A CG 1 ATOM 832 O OD1 . ASN A 1 104 ? 120.887 583.721 84.088 1.00 38.16 ? 136 ASN A OD1 1 ATOM 833 N ND2 . ASN A 1 104 ? 121.096 584.150 81.908 1.00 37.70 ? 136 ASN A ND2 1 ATOM 834 N N . SER A 1 105 ? 125.633 583.217 83.618 1.00 37.92 ? 137 SER A N 1 ATOM 835 C CA . SER A 1 105 ? 126.326 582.264 82.772 1.00 37.15 ? 137 SER A CA 1 ATOM 836 C C . SER A 1 105 ? 127.669 581.898 83.333 1.00 41.59 ? 137 SER A C 1 ATOM 837 O O . SER A 1 105 ? 128.345 582.750 83.916 1.00 41.11 ? 137 SER A O 1 ATOM 838 C CB . SER A 1 105 ? 126.541 582.931 81.414 1.00 40.14 ? 137 SER A CB 1 ATOM 839 O OG . SER A 1 105 ? 127.295 582.145 80.512 1.00 52.60 ? 137 SER A OG 1 ATOM 840 N N . VAL A 1 106 ? 128.074 580.634 83.147 1.00 37.65 ? 138 VAL A N 1 ATOM 841 C CA . VAL A 1 106 ? 129.391 580.134 83.542 1.00 35.84 ? 138 VAL A CA 1 ATOM 842 C C . VAL A 1 106 ? 129.922 579.365 82.349 1.00 35.70 ? 138 VAL A C 1 ATOM 843 O O . VAL A 1 106 ? 129.235 578.481 81.851 1.00 34.33 ? 138 VAL A O 1 ATOM 844 C CB . VAL A 1 106 ? 129.342 579.197 84.771 1.00 39.65 ? 138 VAL A CB 1 ATOM 845 C CG1 . VAL A 1 106 ? 130.763 578.791 85.212 1.00 39.52 ? 138 VAL A CG1 1 ATOM 846 C CG2 . VAL A 1 106 ? 128.547 579.810 85.924 1.00 39.04 ? 138 VAL A CG2 1 ATOM 847 N N . GLU A 1 107 ? 131.122 579.690 81.891 1.00 31.40 ? 139 GLU A N 1 ATOM 848 C CA . GLU A 1 107 ? 131.778 578.949 80.812 1.00 30.74 ? 139 GLU A CA 1 ATOM 849 C C . GLU A 1 107 ? 132.812 578.054 81.459 1.00 33.54 ? 139 GLU A C 1 ATOM 850 O O . GLU A 1 107 ? 133.647 578.525 82.231 1.00 30.97 ? 139 GLU A O 1 ATOM 851 C CB . GLU A 1 107 ? 132.450 579.855 79.765 1.00 31.87 ? 139 GLU A CB 1 ATOM 852 C CG . GLU A 1 107 ? 133.174 579.075 78.677 1.00 37.54 ? 139 GLU A CG 1 ATOM 853 C CD . GLU A 1 107 ? 134.113 579.887 77.806 1.00 61.42 ? 139 GLU A CD 1 ATOM 854 O OE1 . GLU A 1 107 ? 133.641 580.587 76.881 1.00 49.47 ? 139 GLU A OE1 1 ATOM 855 O OE2 . GLU A 1 107 ? 135.339 579.793 78.029 1.00 65.69 ? 139 GLU A OE2 1 ATOM 856 N N . LEU A 1 108 ? 132.770 576.768 81.096 1.00 31.99 ? 140 LEU A N 1 ATOM 857 C CA . LEU A 1 108 ? 133.625 575.726 81.627 1.00 32.03 ? 140 LEU A CA 1 ATOM 858 C C . LEU A 1 108 ? 134.499 575.135 80.556 1.00 38.33 ? 140 LEU A C 1 ATOM 859 O O . LEU A 1 108 ? 134.032 574.855 79.454 1.00 38.63 ? 140 LEU A O 1 ATOM 860 C CB . LEU A 1 108 ? 132.755 574.640 82.290 1.00 31.93 ? 140 LEU A CB 1 ATOM 861 C CG . LEU A 1 108 ? 131.863 575.186 83.411 1.00 35.31 ? 140 LEU A CG 1 ATOM 862 C CD1 . LEU A 1 108 ? 130.601 574.433 83.523 1.00 34.90 ? 140 LEU A CD1 1 ATOM 863 C CD2 . LEU A 1 108 ? 132.598 575.266 84.712 1.00 36.44 ? 140 LEU A CD2 1 ATOM 864 N N . THR A 1 109 ? 135.787 574.967 80.850 1.00 35.01 ? 141 THR A N 1 ATOM 865 C CA . THR A 1 109 ? 136.654 574.305 79.886 1.00 33.75 ? 141 THR A CA 1 ATOM 866 C C . THR A 1 109 ? 136.865 572.880 80.383 1.00 33.40 ? 141 THR A C 1 ATOM 867 O O . THR A 1 109 ? 137.109 572.669 81.568 1.00 30.26 ? 141 THR A O 1 ATOM 868 C CB . THR A 1 109 ? 137.958 575.073 79.662 1.00 45.68 ? 141 THR A CB 1 ATOM 869 O OG1 . THR A 1 109 ? 137.657 576.345 79.089 1.00 45.63 ? 141 THR A OG1 1 ATOM 870 C CG2 . THR A 1 109 ? 138.910 574.331 78.744 1.00 42.46 ? 141 THR A CG2 1 ATOM 871 N N . VAL A 1 110 ? 136.792 571.908 79.468 1.00 29.57 ? 142 VAL A N 1 ATOM 872 C CA . VAL A 1 110 ? 137.011 570.496 79.781 1.00 27.98 ? 142 VAL A CA 1 ATOM 873 C C . VAL A 1 110 ? 138.511 570.227 79.623 1.00 35.15 ? 142 VAL A C 1 ATOM 874 O O . VAL A 1 110 ? 139.046 570.389 78.512 1.00 35.45 ? 142 VAL A O 1 ATOM 875 C CB . VAL A 1 110 ? 136.163 569.600 78.863 1.00 28.95 ? 142 VAL A CB 1 ATOM 876 C CG1 . VAL A 1 110 ? 136.354 568.132 79.208 1.00 27.50 ? 142 VAL A CG1 1 ATOM 877 C CG2 . VAL A 1 110 ? 134.694 569.991 78.941 1.00 28.42 ? 142 VAL A CG2 1 ATOM 878 N N . ALA A 1 111 ? 139.180 569.811 80.727 1.00 32.64 ? 143 ALA A N 1 ATOM 879 C CA . ALA A 1 111 ? 140.638 569.609 80.820 1.00 33.93 ? 143 ALA A CA 1 ATOM 880 C C . ALA A 1 111 ? 141.351 570.853 80.265 1.00 39.93 ? 143 ALA A C 1 ATOM 881 O O . ALA A 1 111 ? 141.088 571.951 80.759 1.00 39.37 ? 143 ALA A O 1 ATOM 882 C CB . ALA A 1 111 ? 141.085 568.326 80.120 1.00 34.52 ? 143 ALA A CB 1 ATOM 883 N N . GLU A 1 112 ? 142.156 570.704 79.207 1.00 38.41 ? 144 GLU A N 1 ATOM 884 C CA . GLU A 1 112 ? 142.870 571.821 78.594 1.00 38.94 ? 144 GLU A CA 1 ATOM 885 C C . GLU A 1 112 ? 142.273 572.110 77.213 1.00 45.25 ? 144 GLU A C 1 ATOM 886 O O . GLU A 1 112 ? 142.980 572.546 76.300 1.00 46.38 ? 144 GLU A O 1 ATOM 887 C CB . GLU A 1 112 ? 144.381 571.532 78.527 1.00 40.33 ? 144 GLU A CB 1 ATOM 888 C CG . GLU A 1 112 ? 145.038 571.241 79.876 1.00 58.02 ? 144 GLU A CG 1 ATOM 889 C CD . GLU A 1 112 ? 144.901 569.816 80.396 1.00 90.90 ? 144 GLU A CD 1 ATOM 890 O OE1 . GLU A 1 112 ? 145.403 568.886 79.723 1.00 88.86 ? 144 GLU A OE1 1 ATOM 891 O OE2 . GLU A 1 112 ? 144.292 569.630 81.477 1.00 87.08 ? 144 GLU A OE2 1 ATOM 892 N N . GLY A 1 113 ? 140.973 571.872 77.060 1.00 40.51 ? 145 GLY A N 1 ATOM 893 C CA . GLY A 1 113 ? 140.336 572.105 75.778 1.00 39.90 ? 145 GLY A CA 1 ATOM 894 C C . GLY A 1 113 ? 140.610 571.020 74.748 1.00 43.06 ? 145 GLY A C 1 ATOM 895 O O . GLY A 1 113 ? 141.328 570.048 75.011 1.00 43.01 ? 145 GLY A O 1 ATOM 896 N N . PRO A 1 114 ? 139.994 571.130 73.568 1.00 38.62 ? 146 PRO A N 1 ATOM 897 C CA . PRO A 1 114 ? 139.169 572.257 73.082 1.00 38.59 ? 146 PRO A CA 1 ATOM 898 C C . PRO A 1 114 ? 137.687 572.268 73.495 1.00 43.52 ? 146 PRO A C 1 ATOM 899 O O . PRO A 1 114 ? 136.972 573.195 73.106 1.00 44.57 ? 146 PRO A O 1 ATOM 900 C CB . PRO A 1 114 ? 139.317 572.135 71.561 1.00 39.65 ? 146 PRO A CB 1 ATOM 901 C CG . PRO A 1 114 ? 139.455 570.660 71.328 1.00 43.17 ? 146 PRO A CG 1 ATOM 902 C CD . PRO A 1 114 ? 140.205 570.117 72.515 1.00 38.90 ? 146 PRO A CD 1 ATOM 903 N N . TYR A 1 115 ? 137.200 571.237 74.211 1.00 38.20 ? 147 TYR A N 1 ATOM 904 C CA . TYR A 1 115 ? 135.786 571.177 74.581 1.00 36.75 ? 147 TYR A CA 1 ATOM 905 C C . TYR A 1 115 ? 135.425 572.181 75.665 1.00 39.98 ? 147 TYR A C 1 ATOM 906 O O . TYR A 1 115 ? 136.216 572.430 76.574 1.00 39.79 ? 147 TYR A O 1 ATOM 907 C CB . TYR A 1 115 ? 135.360 569.753 74.950 1.00 36.98 ? 147 TYR A CB 1 ATOM 908 C CG . TYR A 1 115 ? 135.436 568.821 73.762 1.00 38.06 ? 147 TYR A CG 1 ATOM 909 C CD1 . TYR A 1 115 ? 134.374 568.713 72.867 1.00 39.50 ? 147 TYR A CD1 1 ATOM 910 C CD2 . TYR A 1 115 ? 136.595 568.095 73.491 1.00 38.08 ? 147 TYR A CD2 1 ATOM 911 C CE1 . TYR A 1 115 ? 134.454 567.888 71.747 1.00 37.92 ? 147 TYR A CE1 1 ATOM 912 C CE2 . TYR A 1 115 ? 136.675 567.250 72.385 1.00 38.19 ? 147 TYR A CE2 1 ATOM 913 C CZ . TYR A 1 115 ? 135.594 567.137 71.528 1.00 42.01 ? 147 TYR A CZ 1 ATOM 914 O OH . TYR A 1 115 ? 135.649 566.302 70.450 1.00 39.23 ? 147 TYR A OH 1 ATOM 915 N N . LYS A 1 116 ? 134.253 572.782 75.533 1.00 36.01 ? 148 LYS A N 1 ATOM 916 C CA . LYS A 1 116 ? 133.748 573.809 76.430 1.00 35.75 ? 148 LYS A CA 1 ATOM 917 C C . LYS A 1 116 ? 132.272 573.582 76.643 1.00 40.15 ? 148 LYS A C 1 ATOM 918 O O . LYS A 1 116 ? 131.594 573.052 75.761 1.00 40.46 ? 148 LYS A O 1 ATOM 919 C CB . LYS A 1 116 ? 133.973 575.211 75.832 1.00 37.74 ? 148 LYS A CB 1 ATOM 920 C CG . LYS A 1 116 ? 135.400 575.726 75.976 1.00 51.04 ? 148 LYS A CG 1 ATOM 921 C CD . LYS A 1 116 ? 135.637 577.013 75.205 1.00 62.04 ? 148 LYS A CD 1 ATOM 922 C CE . LYS A 1 116 ? 136.639 576.823 74.101 1.00 77.50 ? 148 LYS A CE 1 ATOM 923 N NZ . LYS A 1 116 ? 136.751 578.044 73.253 1.00 86.47 ? 148 LYS A NZ 1 ATOM 924 N N . ILE A 1 117 ? 131.786 573.966 77.822 1.00 34.51 ? 149 ILE A N 1 ATOM 925 C CA . ILE A 1 117 ? 130.400 573.848 78.222 1.00 33.64 ? 149 ILE A CA 1 ATOM 926 C C . ILE A 1 117 ? 129.955 575.180 78.774 1.00 35.55 ? 149 ILE A C 1 ATOM 927 O O . ILE A 1 117 ? 130.610 575.737 79.650 1.00 34.61 ? 149 ILE A O 1 ATOM 928 C CB . ILE A 1 117 ? 130.197 572.724 79.284 1.00 36.54 ? 149 ILE A CB 1 ATOM 929 C CG1 . ILE A 1 117 ? 130.799 571.381 78.817 1.00 36.58 ? 149 ILE A CG1 1 ATOM 930 C CG2 . ILE A 1 117 ? 128.711 572.592 79.638 1.00 36.69 ? 149 ILE A CG2 1 ATOM 931 C CD1 . ILE A 1 117 ? 130.715 570.237 79.806 1.00 44.53 ? 149 ILE A CD1 1 ATOM 932 N N . ILE A 1 118 ? 128.841 575.688 78.277 1.00 32.66 ? 150 ILE A N 1 ATOM 933 C CA . ILE A 1 118 ? 128.263 576.919 78.787 1.00 31.65 ? 150 ILE A CA 1 ATOM 934 C C . ILE A 1 118 ? 127.013 576.573 79.560 1.00 34.71 ? 150 ILE A C 1 ATOM 935 O O . ILE A 1 118 ? 126.045 576.064 78.985 1.00 33.56 ? 150 ILE A O 1 ATOM 936 C CB . ILE A 1 118 ? 127.962 577.980 77.706 1.00 34.56 ? 150 ILE A CB 1 ATOM 937 C CG1 . ILE A 1 118 ? 129.242 578.327 76.935 1.00 35.26 ? 150 ILE A CG1 1 ATOM 938 C CG2 . ILE A 1 118 ? 127.325 579.267 78.351 1.00 34.11 ? 150 ILE A CG2 1 ATOM 939 C CD1 . ILE A 1 118 ? 129.023 579.145 75.693 1.00 40.85 ? 150 ILE A CD1 1 ATOM 940 N N . LEU A 1 119 ? 127.024 576.885 80.856 1.00 30.82 ? 151 LEU A N 1 ATOM 941 C CA . LEU A 1 119 ? 125.858 576.740 81.695 1.00 30.27 ? 151 LEU A CA 1 ATOM 942 C C . LEU A 1 119 ? 125.170 578.127 81.806 1.00 36.35 ? 151 LEU A C 1 ATOM 943 O O . LEU A 1 119 ? 125.785 579.083 82.262 1.00 35.70 ? 151 LEU A O 1 ATOM 944 C CB . LEU A 1 119 ? 126.292 576.230 83.060 1.00 29.69 ? 151 LEU A CB 1 ATOM 945 C CG . LEU A 1 119 ? 125.307 576.390 84.205 1.00 34.22 ? 151 LEU A CG 1 ATOM 946 C CD1 . LEU A 1 119 ? 124.093 575.497 84.019 1.00 34.93 ? 151 LEU A CD1 1 ATOM 947 C CD2 . LEU A 1 119 ? 125.984 576.108 85.527 1.00 34.14 ? 151 LEU A CD2 1 ATOM 948 N N . THR A 1 120 ? 123.907 578.223 81.394 1.00 34.87 ? 152 THR A N 1 ATOM 949 C CA . THR A 1 120 ? 123.127 579.457 81.505 1.00 35.49 ? 152 THR A CA 1 ATOM 950 C C . THR A 1 120 ? 122.209 579.234 82.677 1.00 40.76 ? 152 THR A C 1 ATOM 951 O O . THR A 1 120 ? 121.523 578.213 82.719 1.00 41.49 ? 152 THR A O 1 ATOM 952 C CB . THR A 1 120 ? 122.326 579.754 80.218 1.00 39.19 ? 152 THR A CB 1 ATOM 953 O OG1 . THR A 1 120 ? 123.238 579.887 79.118 1.00 28.92 ? 152 THR A OG1 1 ATOM 954 C CG2 . THR A 1 120 ? 121.486 581.033 80.334 1.00 39.30 ? 152 THR A CG2 1 ATOM 955 N N . ALA A 1 121 ? 122.155 580.187 83.605 1.00 36.36 ? 153 ALA A N 1 ATOM 956 C CA . ALA A 1 121 ? 121.316 580.035 84.781 1.00 35.84 ? 153 ALA A CA 1 ATOM 957 C C . ALA A 1 121 ? 119.817 580.199 84.517 1.00 38.94 ? 153 ALA A C 1 ATOM 958 O O . ALA A 1 121 ? 119.052 579.335 84.924 1.00 39.13 ? 153 ALA A O 1 ATOM 959 C CB . ALA A 1 121 ? 121.780 580.970 85.891 1.00 36.55 ? 153 ALA A CB 1 ATOM 960 N N . GLN A 1 122 ? 119.396 581.297 83.863 1.00 35.96 ? 154 GLN A N 1 ATOM 961 C CA . GLN A 1 122 ? 117.986 581.568 83.612 1.00 35.61 ? 154 GLN A CA 1 ATOM 962 C C . GLN A 1 122 ? 117.725 581.942 82.168 1.00 38.23 ? 154 GLN A C 1 ATOM 963 O O . GLN A 1 122 ? 118.204 582.970 81.715 1.00 40.56 ? 154 GLN A O 1 ATOM 964 C CB . GLN A 1 122 ? 117.443 582.650 84.557 1.00 37.29 ? 154 GLN A CB 1 ATOM 965 C CG . GLN A 1 122 ? 115.922 582.909 84.388 1.00 61.05 ? 154 GLN A CG 1 ATOM 966 C CD . GLN A 1 122 ? 115.294 583.800 85.440 1.00 78.88 ? 154 GLN A CD 1 ATOM 967 O OE1 . GLN A 1 122 ? 115.968 584.510 86.201 1.00 73.48 ? 154 GLN A OE1 1 ATOM 968 N NE2 . GLN A 1 122 ? 113.970 583.779 85.500 1.00 70.56 ? 154 GLN A NE2 1 ATOM 969 N N . PRO A 1 123 ? 116.936 581.159 81.430 1.00 32.19 ? 155 PRO A N 1 ATOM 970 C CA . PRO A 1 123 ? 116.432 579.836 81.798 1.00 31.18 ? 155 PRO A CA 1 ATOM 971 C C . PRO A 1 123 ? 117.590 578.848 81.756 1.00 32.92 ? 155 PRO A C 1 ATOM 972 O O . PRO A 1 123 ? 118.598 579.081 81.078 1.00 30.81 ? 155 PRO A O 1 ATOM 973 C CB . PRO A 1 123 ? 115.417 579.538 80.693 1.00 32.75 ? 155 PRO A CB 1 ATOM 974 C CG . PRO A 1 123 ? 115.959 580.238 79.502 1.00 37.45 ? 155 PRO A CG 1 ATOM 975 C CD . PRO A 1 123 ? 116.642 581.479 80.021 1.00 33.08 ? 155 PRO A CD 1 ATOM 976 N N . PHE A 1 124 ? 117.457 577.766 82.511 1.00 30.74 ? 156 PHE A N 1 ATOM 977 C CA . PHE A 1 124 ? 118.487 576.734 82.550 1.00 30.79 ? 156 PHE A CA 1 ATOM 978 C C . PHE A 1 124 ? 118.737 576.166 81.152 1.00 31.36 ? 156 PHE A C 1 ATOM 979 O O . PHE A 1 124 ? 117.810 575.777 80.451 1.00 29.86 ? 156 PHE A O 1 ATOM 980 C CB . PHE A 1 124 ? 118.111 575.609 83.517 1.00 32.18 ? 156 PHE A CB 1 ATOM 981 C CG . PHE A 1 124 ? 118.969 574.379 83.375 1.00 33.40 ? 156 PHE A CG 1 ATOM 982 C CD1 . PHE A 1 124 ? 120.335 574.430 83.640 1.00 34.90 ? 156 PHE A CD1 1 ATOM 983 C CD2 . PHE A 1 124 ? 118.413 573.165 82.988 1.00 34.81 ? 156 PHE A CD2 1 ATOM 984 C CE1 . PHE A 1 124 ? 121.119 573.297 83.516 1.00 34.26 ? 156 PHE A CE1 1 ATOM 985 C CE2 . PHE A 1 124 ? 119.206 572.030 82.864 1.00 36.13 ? 156 PHE A CE2 1 ATOM 986 C CZ . PHE A 1 124 ? 120.546 572.101 83.148 1.00 33.74 ? 156 PHE A CZ 1 ATOM 987 N N . ARG A 1 125 ? 119.994 576.166 80.763 1.00 26.61 ? 157 ARG A N 1 ATOM 988 C CA . ARG A 1 125 ? 120.440 575.660 79.486 1.00 25.38 ? 157 ARG A CA 1 ATOM 989 C C . ARG A 1 125 ? 121.889 575.237 79.611 1.00 28.19 ? 157 ARG A C 1 ATOM 990 O O . ARG A 1 125 ? 122.641 575.817 80.403 1.00 26.55 ? 157 ARG A O 1 ATOM 991 C CB . ARG A 1 125 ? 120.313 576.760 78.424 1.00 24.26 ? 157 ARG A CB 1 ATOM 992 C CG . ARG A 1 125 ? 120.643 576.313 77.011 1.00 26.79 ? 157 ARG A CG 1 ATOM 993 C CD . ARG A 1 125 ? 120.762 577.512 76.123 1.00 21.27 ? 157 ARG A CD 1 ATOM 994 N NE . ARG A 1 125 ? 121.039 577.139 74.741 1.00 32.63 ? 157 ARG A NE 1 ATOM 995 C CZ . ARG A 1 125 ? 120.164 577.234 73.744 1.00 45.12 ? 157 ARG A CZ 1 ATOM 996 N NH1 . ARG A 1 125 ? 118.937 577.684 73.969 1.00 40.73 ? 157 ARG A NH1 1 ATOM 997 N NH2 . ARG A 1 125 ? 120.517 576.896 72.511 1.00 27.20 ? 157 ARG A NH2 1 ATOM 998 N N . LEU A 1 126 ? 122.263 574.196 78.849 1.00 24.61 ? 158 LEU A N 1 ATOM 999 C CA . LEU A 1 126 ? 123.648 573.800 78.673 1.00 24.25 ? 158 LEU A CA 1 ATOM 1000 C C . LEU A 1 126 ? 123.967 573.851 77.188 1.00 29.44 ? 158 LEU A C 1 ATOM 1001 O O . LEU A 1 126 ? 123.142 573.467 76.371 1.00 28.27 ? 158 LEU A O 1 ATOM 1002 C CB . LEU A 1 126 ? 123.953 572.408 79.218 1.00 24.28 ? 158 LEU A CB 1 ATOM 1003 C CG . LEU A 1 126 ? 123.837 572.189 80.734 1.00 28.33 ? 158 LEU A CG 1 ATOM 1004 C CD1 . LEU A 1 126 ? 123.775 570.723 81.037 1.00 27.98 ? 158 LEU A CD1 1 ATOM 1005 C CD2 . LEU A 1 126 ? 125.021 572.783 81.479 1.00 29.48 ? 158 LEU A CD2 1 ATOM 1006 N N . ASP A 1 127 ? 125.148 574.339 76.838 1.00 29.22 ? 159 ASP A N 1 ATOM 1007 C CA . ASP A 1 127 ? 125.652 574.331 75.466 1.00 29.58 ? 159 ASP A CA 1 ATOM 1008 C C . ASP A 1 127 ? 127.015 573.636 75.479 1.00 33.70 ? 159 ASP A C 1 ATOM 1009 O O . ASP A 1 127 ? 127.844 573.931 76.334 1.00 33.84 ? 159 ASP A O 1 ATOM 1010 C CB . ASP A 1 127 ? 125.767 575.742 74.875 1.00 31.26 ? 159 ASP A CB 1 ATOM 1011 C CG . ASP A 1 127 ? 124.456 576.509 74.817 1.00 39.51 ? 159 ASP A CG 1 ATOM 1012 O OD1 . ASP A 1 127 ? 123.558 576.100 74.047 1.00 38.46 ? 159 ASP A OD1 1 ATOM 1013 O OD2 . ASP A 1 127 ? 124.364 577.568 75.468 1.00 45.01 ? 159 ASP A OD2 1 ATOM 1014 N N . LEU A 1 128 ? 127.221 572.672 74.572 1.00 30.17 ? 160 LEU A N 1 ATOM 1015 C CA . LEU A 1 128 ? 128.477 571.918 74.467 1.00 29.30 ? 160 LEU A CA 1 ATOM 1016 C C . LEU A 1 128 ? 129.146 572.313 73.172 1.00 31.33 ? 160 LEU A C 1 ATOM 1017 O O . LEU A 1 128 ? 128.529 572.233 72.109 1.00 29.13 ? 160 LEU A O 1 ATOM 1018 C CB . LEU A 1 128 ? 128.218 570.403 74.477 1.00 29.29 ? 160 LEU A CB 1 ATOM 1019 C CG . LEU A 1 128 ? 127.930 569.749 75.814 1.00 34.27 ? 160 LEU A CG 1 ATOM 1020 C CD1 . LEU A 1 128 ? 126.542 570.097 76.334 1.00 35.19 ? 160 LEU A CD1 1 ATOM 1021 C CD2 . LEU A 1 128 ? 127.985 568.274 75.695 1.00 35.94 ? 160 LEU A CD2 1 ATOM 1022 N N . LEU A 1 129 ? 130.388 572.774 73.261 1.00 28.60 ? 161 LEU A N 1 ATOM 1023 C CA . LEU A 1 129 ? 131.122 573.239 72.094 1.00 28.59 ? 161 LEU A CA 1 ATOM 1024 C C . LEU A 1 129 ? 132.460 572.572 71.977 1.00 34.77 ? 161 LEU A C 1 ATOM 1025 O O . LEU A 1 129 ? 132.989 572.059 72.959 1.00 34.53 ? 161 LEU A O 1 ATOM 1026 C CB . LEU A 1 129 ? 131.335 574.769 72.165 1.00 28.15 ? 161 LEU A CB 1 ATOM 1027 C CG . LEU A 1 129 ? 130.053 575.612 72.293 1.00 32.64 ? 161 LEU A CG 1 ATOM 1028 C CD1 . LEU A 1 129 ? 129.809 576.036 73.734 1.00 32.25 ? 161 LEU A CD1 1 ATOM 1029 C CD2 . LEU A 1 129 ? 130.099 576.821 71.374 1.00 36.00 ? 161 LEU A CD2 1 ATOM 1030 N N . GLU A 1 130 ? 132.991 572.539 70.763 1.00 33.75 ? 162 GLU A N 1 ATOM 1031 C CA . GLU A 1 130 ? 134.392 572.214 70.506 1.00 34.33 ? 162 GLU A CA 1 ATOM 1032 C C . GLU A 1 130 ? 134.957 573.500 69.928 1.00 40.25 ? 162 GLU A C 1 ATOM 1033 O O . GLU A 1 130 ? 134.623 573.876 68.793 1.00 38.70 ? 162 GLU A O 1 ATOM 1034 C CB . GLU A 1 130 ? 134.661 571.038 69.568 1.00 35.69 ? 162 GLU A CB 1 ATOM 1035 C CG . GLU A 1 130 ? 136.157 570.751 69.511 1.00 43.37 ? 162 GLU A CG 1 ATOM 1036 C CD . GLU A 1 130 ? 136.669 569.782 68.465 1.00 51.49 ? 162 GLU A CD 1 ATOM 1037 O OE1 . GLU A 1 130 ? 135.909 568.880 68.053 1.00 50.18 ? 162 GLU A OE1 1 ATOM 1038 O OE2 . GLU A 1 130 ? 137.856 569.901 68.086 1.00 37.96 ? 162 GLU A OE2 1 ATOM 1039 N N . ASP A 1 131 ? 135.776 574.190 70.733 1.00 39.96 ? 163 ASP A N 1 ATOM 1040 C CA . ASP A 1 131 ? 136.346 575.490 70.380 1.00 42.27 ? 163 ASP A CA 1 ATOM 1041 C C . ASP A 1 131 ? 135.194 576.492 70.088 1.00 47.72 ? 163 ASP A C 1 ATOM 1042 O O . ASP A 1 131 ? 134.427 576.793 71.000 1.00 47.31 ? 163 ASP A O 1 ATOM 1043 C CB . ASP A 1 131 ? 137.387 575.366 69.232 1.00 45.21 ? 163 ASP A CB 1 ATOM 1044 C CG . ASP A 1 131 ? 138.258 576.585 69.069 1.00 64.70 ? 163 ASP A CG 1 ATOM 1045 O OD1 . ASP A 1 131 ? 138.308 577.412 70.014 1.00 66.12 ? 163 ASP A OD1 1 ATOM 1046 O OD2 . ASP A 1 131 ? 138.886 576.724 67.996 1.00 75.76 ? 163 ASP A OD2 1 ATOM 1047 N N . ARG A 1 132 ? 134.995 576.882 68.821 1.00 45.77 ? 164 ARG A N 1 ATOM 1048 C CA . ARG A 1 132 ? 133.944 577.803 68.390 1.00 45.86 ? 164 ARG A CA 1 ATOM 1049 C C . ARG A 1 132 ? 132.734 577.109 67.745 1.00 45.82 ? 164 ARG A C 1 ATOM 1050 O O . ARG A 1 132 ? 131.753 577.784 67.402 1.00 45.23 ? 164 ARG A O 1 ATOM 1051 C CB . ARG A 1 132 ? 134.550 578.857 67.443 1.00 50.43 ? 164 ARG A CB 1 ATOM 1052 C CG . ARG A 1 132 ? 135.767 579.553 68.061 1.00 68.56 ? 164 ARG A CG 1 ATOM 1053 C CD . ARG A 1 132 ? 136.299 580.691 67.231 1.00 88.41 ? 164 ARG A CD 1 ATOM 1054 N NE . ARG A 1 132 ? 137.030 581.651 68.065 1.00 100.87 ? 164 ARG A NE 1 ATOM 1055 C CZ . ARG A 1 132 ? 137.125 582.957 67.815 1.00 114.95 ? 164 ARG A CZ 1 ATOM 1056 N NH1 . ARG A 1 132 ? 136.540 583.481 66.741 1.00 103.70 ? 164 ARG A NH1 1 ATOM 1057 N NH2 . ARG A 1 132 ? 137.805 583.748 68.634 1.00 96.96 ? 164 ARG A NH2 1 ATOM 1058 N N . SER A 1 133 ? 132.786 575.778 67.580 1.00 38.76 ? 165 SER A N 1 ATOM 1059 C CA . SER A 1 133 ? 131.662 575.064 66.985 1.00 37.55 ? 165 SER A CA 1 ATOM 1060 C C . SER A 1 133 ? 130.708 574.551 68.038 1.00 38.04 ? 165 SER A C 1 ATOM 1061 O O . SER A 1 133 ? 131.115 573.761 68.880 1.00 37.39 ? 165 SER A O 1 ATOM 1062 C CB . SER A 1 133 ? 132.136 573.893 66.135 1.00 42.60 ? 165 SER A CB 1 ATOM 1063 O OG . SER A 1 133 ? 133.206 574.294 65.303 1.00 59.57 ? 165 SER A OG 1 ATOM 1064 N N . LEU A 1 134 ? 129.434 574.972 67.968 1.00 32.79 ? 166 LEU A N 1 ATOM 1065 C CA . LEU A 1 134 ? 128.360 574.496 68.838 1.00 30.97 ? 166 LEU A CA 1 ATOM 1066 C C . LEU A 1 134 ? 127.954 573.095 68.379 1.00 34.59 ? 166 LEU A C 1 ATOM 1067 O O . LEU A 1 134 ? 127.542 572.896 67.228 1.00 35.28 ? 166 LEU A O 1 ATOM 1068 C CB . LEU A 1 134 ? 127.148 575.441 68.784 1.00 30.54 ? 166 LEU A CB 1 ATOM 1069 C CG . LEU A 1 134 ? 125.846 575.005 69.529 1.00 33.05 ? 166 LEU A CG 1 ATOM 1070 C CD1 . LEU A 1 134 ? 126.064 574.990 71.031 1.00 31.69 ? 166 LEU A CD1 1 ATOM 1071 C CD2 . LEU A 1 134 ? 124.704 575.924 69.178 1.00 33.52 ? 166 LEU A CD2 1 ATOM 1072 N N . LEU A 1 135 ? 128.066 572.131 69.281 1.00 28.96 ? 167 LEU A N 1 ATOM 1073 C CA . LEU A 1 135 ? 127.756 570.752 68.966 1.00 27.98 ? 167 LEU A CA 1 ATOM 1074 C C . LEU A 1 135 ? 126.369 570.381 69.357 1.00 31.45 ? 167 LEU A C 1 ATOM 1075 O O . LEU A 1 135 ? 125.698 569.631 68.638 1.00 29.01 ? 167 LEU A O 1 ATOM 1076 C CB . LEU A 1 135 ? 128.762 569.826 69.655 1.00 27.39 ? 167 LEU A CB 1 ATOM 1077 C CG . LEU A 1 135 ? 130.231 570.190 69.442 1.00 31.00 ? 167 LEU A CG 1 ATOM 1078 C CD1 . LEU A 1 135 ? 131.113 569.281 70.219 1.00 29.84 ? 167 LEU A CD1 1 ATOM 1079 C CD2 . LEU A 1 135 ? 130.589 570.160 67.970 1.00 32.41 ? 167 LEU A CD2 1 ATOM 1080 N N . LEU A 1 136 ? 125.936 570.867 70.516 1.00 29.91 ? 168 LEU A N 1 ATOM 1081 C CA . LEU A 1 136 ? 124.658 570.464 71.053 1.00 30.39 ? 168 LEU A CA 1 ATOM 1082 C C . LEU A 1 136 ? 124.193 571.368 72.182 1.00 30.68 ? 168 LEU A C 1 ATOM 1083 O O . LEU A 1 136 ? 124.991 571.873 72.975 1.00 28.79 ? 168 LEU A O 1 ATOM 1084 C CB . LEU A 1 136 ? 124.924 569.015 71.513 1.00 31.24 ? 168 LEU A CB 1 ATOM 1085 C CG . LEU A 1 136 ? 124.035 568.152 72.328 1.00 37.23 ? 168 LEU A CG 1 ATOM 1086 C CD1 . LEU A 1 136 ? 124.574 566.744 72.221 1.00 37.47 ? 168 LEU A CD1 1 ATOM 1087 C CD2 . LEU A 1 136 ? 124.068 568.574 73.791 1.00 39.18 ? 168 LEU A CD2 1 ATOM 1088 N N . SER A 1 137 ? 122.893 571.558 72.254 1.00 26.05 ? 169 SER A N 1 ATOM 1089 C CA . SER A 1 137 ? 122.308 572.303 73.352 1.00 25.77 ? 169 SER A CA 1 ATOM 1090 C C . SER A 1 137 ? 121.343 571.416 74.105 1.00 27.70 ? 169 SER A C 1 ATOM 1091 O O . SER A 1 137 ? 120.757 570.509 73.523 1.00 25.94 ? 169 SER A O 1 ATOM 1092 C CB . SER A 1 137 ? 121.600 573.555 72.872 1.00 29.17 ? 169 SER A CB 1 ATOM 1093 O OG . SER A 1 137 ? 122.546 574.424 72.288 1.00 44.67 ? 169 SER A OG 1 ATOM 1094 N N . VAL A 1 138 ? 121.183 571.692 75.396 1.00 24.34 ? 170 VAL A N 1 ATOM 1095 C CA . VAL A 1 138 ? 120.317 570.961 76.318 1.00 25.09 ? 170 VAL A CA 1 ATOM 1096 C C . VAL A 1 138 ? 119.314 571.927 76.893 1.00 29.24 ? 170 VAL A C 1 ATOM 1097 O O . VAL A 1 138 ? 119.699 572.953 77.468 1.00 28.43 ? 170 VAL A O 1 ATOM 1098 C CB . VAL A 1 138 ? 121.141 570.317 77.464 1.00 30.19 ? 170 VAL A CB 1 ATOM 1099 C CG1 . VAL A 1 138 ? 120.263 569.459 78.365 1.00 30.09 ? 170 VAL A CG1 1 ATOM 1100 C CG2 . VAL A 1 138 ? 122.317 569.511 76.934 1.00 30.12 ? 170 VAL A CG2 1 ATOM 1101 N N . ASN A 1 139 ? 118.032 571.578 76.772 1.00 27.63 ? 171 ASN A N 1 ATOM 1102 C CA . ASN A 1 139 ? 116.887 572.368 77.231 1.00 28.48 ? 171 ASN A CA 1 ATOM 1103 C C . ASN A 1 139 ? 116.679 573.645 76.376 1.00 34.58 ? 171 ASN A C 1 ATOM 1104 O O . ASN A 1 139 ? 115.997 574.568 76.809 1.00 34.11 ? 171 ASN A O 1 ATOM 1105 C CB . ASN A 1 139 ? 116.947 572.672 78.750 1.00 25.18 ? 171 ASN A CB 1 ATOM 1106 C CG . ASN A 1 139 ? 115.606 573.008 79.360 1.00 41.63 ? 171 ASN A CG 1 ATOM 1107 O OD1 . ASN A 1 139 ? 114.559 572.467 78.989 1.00 35.36 ? 171 ASN A OD1 1 ATOM 1108 N ND2 . ASN A 1 139 ? 115.611 573.928 80.305 1.00 32.26 ? 171 ASN A ND2 1 ATOM 1109 N N . ALA A 1 140 ? 117.195 573.657 75.133 1.00 32.71 ? 172 ALA A N 1 ATOM 1110 C CA . ALA A 1 140 ? 117.052 574.794 74.227 1.00 32.42 ? 172 ALA A CA 1 ATOM 1111 C C . ALA A 1 140 ? 115.588 575.135 73.925 1.00 37.15 ? 172 ALA A C 1 ATOM 1112 O O . ALA A 1 140 ? 115.275 576.314 73.789 1.00 37.47 ? 172 ALA A O 1 ATOM 1113 C CB . ALA A 1 140 ? 117.819 574.549 72.949 1.00 33.08 ? 172 ALA A CB 1 ATOM 1114 N N . ARG A 1 141 ? 114.682 574.126 73.886 1.00 32.50 ? 173 ARG A N 1 ATOM 1115 C CA . ARG A 1 141 ? 113.253 574.340 73.647 1.00 30.41 ? 173 ARG A CA 1 ATOM 1116 C C . ARG A 1 141 ? 112.444 574.379 74.943 1.00 33.52 ? 173 ARG A C 1 ATOM 1117 O O . ARG A 1 141 ? 111.214 574.385 74.910 1.00 35.97 ? 173 ARG A O 1 ATOM 1118 C CB . ARG A 1 141 ? 112.703 573.311 72.655 1.00 29.15 ? 173 ARG A CB 1 ATOM 1119 C CG . ARG A 1 141 ? 113.221 573.498 71.223 1.00 31.50 ? 173 ARG A CG 1 ATOM 1120 C CD . ARG A 1 141 ? 112.511 572.534 70.292 1.00 47.85 ? 173 ARG A CD 1 ATOM 1121 N NE . ARG A 1 141 ? 112.808 571.143 70.651 1.00 67.94 ? 173 ARG A NE 1 ATOM 1122 C CZ . ARG A 1 141 ? 111.967 570.115 70.539 1.00 81.22 ? 173 ARG A CZ 1 ATOM 1123 N NH1 . ARG A 1 141 ? 110.738 570.299 70.065 1.00 65.13 ? 173 ARG A NH1 1 ATOM 1124 N NH2 . ARG A 1 141 ? 112.344 568.899 70.914 1.00 64.41 ? 173 ARG A NH2 1 ATOM 1125 N N . GLY A 1 142 ? 113.138 574.429 76.072 1.00 27.33 ? 174 GLY A N 1 ATOM 1126 C CA . GLY A 1 142 ? 112.537 574.459 77.397 1.00 26.57 ? 174 GLY A CA 1 ATOM 1127 C C . GLY A 1 142 ? 111.645 573.286 77.724 1.00 31.11 ? 174 GLY A C 1 ATOM 1128 O O . GLY A 1 142 ? 110.638 573.459 78.406 1.00 31.65 ? 174 GLY A O 1 ATOM 1129 N N . LEU A 1 143 ? 111.998 572.088 77.261 1.00 27.75 ? 175 LEU A N 1 ATOM 1130 C CA . LEU A 1 143 ? 111.141 570.931 77.470 1.00 27.21 ? 175 LEU A CA 1 ATOM 1131 C C . LEU A 1 143 ? 111.520 570.085 78.688 1.00 29.06 ? 175 LEU A C 1 ATOM 1132 O O . LEU A 1 143 ? 110.896 569.047 78.919 1.00 27.39 ? 175 LEU A O 1 ATOM 1133 C CB . LEU A 1 143 ? 111.059 570.087 76.191 1.00 27.33 ? 175 LEU A CB 1 ATOM 1134 C CG . LEU A 1 143 ? 110.531 570.838 74.973 1.00 31.55 ? 175 LEU A CG 1 ATOM 1135 C CD1 . LEU A 1 143 ? 110.529 569.943 73.737 1.00 32.03 ? 175 LEU A CD1 1 ATOM 1136 C CD2 . LEU A 1 143 ? 109.132 571.356 75.245 1.00 29.10 ? 175 LEU A CD2 1 ATOM 1137 N N . MET A 1 144 ? 112.511 570.526 79.476 1.00 23.92 ? 176 MET A N 1 ATOM 1138 C CA . MET A 1 144 ? 112.852 569.808 80.700 1.00 23.11 ? 176 MET A CA 1 ATOM 1139 C C . MET A 1 144 ? 111.640 569.717 81.621 1.00 31.82 ? 176 MET A C 1 ATOM 1140 O O . MET A 1 144 ? 110.996 570.725 81.873 1.00 32.84 ? 176 MET A O 1 ATOM 1141 C CB . MET A 1 144 ? 113.982 570.498 81.451 1.00 23.68 ? 176 MET A CB 1 ATOM 1142 C CG . MET A 1 144 ? 114.346 569.760 82.700 1.00 24.56 ? 176 MET A CG 1 ATOM 1143 S SD . MET A 1 144 ? 115.722 570.559 83.448 1.00 26.30 ? 176 MET A SD 1 ATOM 1144 C CE . MET A 1 144 ? 115.613 569.878 85.136 1.00 22.13 ? 176 MET A CE 1 ATOM 1145 N N . ALA A 1 145 ? 111.327 568.520 82.124 1.00 30.70 ? 177 ALA A N 1 ATOM 1146 C CA . ALA A 1 145 ? 110.205 568.329 83.050 1.00 31.03 ? 177 ALA A CA 1 ATOM 1147 C C . ALA A 1 145 ? 110.581 567.264 84.041 1.00 36.05 ? 177 ALA A C 1 ATOM 1148 O O . ALA A 1 145 ? 110.935 566.152 83.649 1.00 36.73 ? 177 ALA A O 1 ATOM 1149 C CB . ALA A 1 145 ? 108.952 567.921 82.299 1.00 31.69 ? 177 ALA A CB 1 ATOM 1150 N N . PHE A 1 146 ? 110.535 567.600 85.316 1.00 32.44 ? 178 PHE A N 1 ATOM 1151 C CA . PHE A 1 146 ? 110.924 566.658 86.351 1.00 31.98 ? 178 PHE A CA 1 ATOM 1152 C C . PHE A 1 146 ? 109.823 566.631 87.350 1.00 31.70 ? 178 PHE A C 1 ATOM 1153 O O . PHE A 1 146 ? 109.698 567.571 88.119 1.00 30.88 ? 178 PHE A O 1 ATOM 1154 C CB . PHE A 1 146 ? 112.254 567.107 86.994 1.00 33.64 ? 178 PHE A CB 1 ATOM 1155 C CG . PHE A 1 146 ? 112.980 566.016 87.746 1.00 35.23 ? 178 PHE A CG 1 ATOM 1156 C CD1 . PHE A 1 146 ? 112.466 565.503 88.931 1.00 38.67 ? 178 PHE A CD1 1 ATOM 1157 C CD2 . PHE A 1 146 ? 114.190 565.519 87.284 1.00 36.44 ? 178 PHE A CD2 1 ATOM 1158 C CE1 . PHE A 1 146 ? 113.156 564.516 89.643 1.00 39.23 ? 178 PHE A CE1 1 ATOM 1159 C CE2 . PHE A 1 146 ? 114.876 564.536 87.999 1.00 39.01 ? 178 PHE A CE2 1 ATOM 1160 C CZ . PHE A 1 146 ? 114.355 564.043 89.174 1.00 37.22 ? 178 PHE A CZ 1 ATOM 1161 N N . GLU A 1 147 ? 108.987 565.597 87.317 1.00 26.79 ? 179 GLU A N 1 ATOM 1162 C CA . GLU A 1 147 ? 107.869 565.536 88.249 1.00 26.17 ? 179 GLU A CA 1 ATOM 1163 C C . GLU A 1 147 ? 108.376 565.027 89.584 1.00 32.01 ? 179 GLU A C 1 ATOM 1164 O O . GLU A 1 147 ? 108.786 563.876 89.679 1.00 30.02 ? 179 GLU A O 1 ATOM 1165 C CB . GLU A 1 147 ? 106.758 564.635 87.713 1.00 26.89 ? 179 GLU A CB 1 ATOM 1166 C CG . GLU A 1 147 ? 106.321 564.992 86.312 1.00 22.97 ? 179 GLU A CG 1 ATOM 1167 C CD . GLU A 1 147 ? 105.105 564.205 85.893 1.00 39.19 ? 179 GLU A CD 1 ATOM 1168 O OE1 . GLU A 1 147 ? 104.052 564.840 85.666 1.00 40.09 ? 179 GLU A OE1 1 ATOM 1169 O OE2 . GLU A 1 147 ? 105.183 562.957 85.838 1.00 36.53 ? 179 GLU A OE2 1 ATOM 1170 N N . HIS A 1 148 ? 108.392 565.891 90.605 1.00 30.52 ? 180 HIS A N 1 ATOM 1171 C CA . HIS A 1 148 ? 108.854 565.523 91.944 1.00 31.09 ? 180 HIS A CA 1 ATOM 1172 C C . HIS A 1 148 ? 107.895 564.559 92.630 1.00 38.08 ? 180 HIS A C 1 ATOM 1173 O O . HIS A 1 148 ? 106.693 564.551 92.324 1.00 38.22 ? 180 HIS A O 1 ATOM 1174 C CB . HIS A 1 148 ? 109.037 566.777 92.806 1.00 31.94 ? 180 HIS A CB 1 ATOM 1175 C CG . HIS A 1 148 ? 107.744 567.378 93.267 1.00 35.49 ? 180 HIS A CG 1 ATOM 1176 N ND1 . HIS A 1 148 ? 106.917 568.080 92.397 1.00 37.26 ? 180 HIS A ND1 1 ATOM 1177 C CD2 . HIS A 1 148 ? 107.189 567.376 94.503 1.00 37.92 ? 180 HIS A CD2 1 ATOM 1178 C CE1 . HIS A 1 148 ? 105.877 568.458 93.123 1.00 37.67 ? 180 HIS A CE1 1 ATOM 1179 N NE2 . HIS A 1 148 ? 105.997 568.058 94.400 1.00 38.22 ? 180 HIS A NE2 1 ATOM 1180 N N . GLN A 1 149 ? 108.428 563.758 93.569 1.00 36.92 ? 181 GLN A N 1 ATOM 1181 C CA . GLN A 1 149 ? 107.635 562.816 94.352 1.00 37.44 ? 181 GLN A CA 1 ATOM 1182 C C . GLN A 1 149 ? 106.707 563.562 95.328 1.00 46.41 ? 181 GLN A C 1 ATOM 1183 O O . GLN A 1 149 ? 107.176 564.251 96.230 1.00 46.35 ? 181 GLN A O 1 ATOM 1184 C CB . GLN A 1 149 ? 108.547 561.828 95.088 1.00 38.02 ? 181 GLN A CB 1 ATOM 1185 C CG . GLN A 1 149 ? 109.240 560.848 94.144 1.00 47.83 ? 181 GLN A CG 1 ATOM 1186 C CD . GLN A 1 149 ? 110.479 560.175 94.713 1.00 54.55 ? 181 GLN A CD 1 ATOM 1187 O OE1 . GLN A 1 149 ? 110.600 558.945 94.721 1.00 55.40 ? 181 GLN A OE1 1 ATOM 1188 N NE2 . GLN A 1 149 ? 111.460 560.956 95.126 1.00 31.57 ? 181 GLN A NE2 1 ATOM 1189 N N . ARG A 1 150 ? 105.395 563.463 95.116 1.00 46.87 ? 182 ARG A N 1 ATOM 1190 C CA . ARG A 1 150 ? 104.401 564.078 96.005 1.00 48.52 ? 182 ARG A CA 1 ATOM 1191 C C . ARG A 1 150 ? 104.092 563.127 97.184 1.00 59.37 ? 182 ARG A C 1 ATOM 1192 O O . ARG A 1 150 ? 104.576 561.998 97.168 1.00 59.00 ? 182 ARG A O 1 ATOM 1193 C CB . ARG A 1 150 ? 103.121 564.370 95.228 1.00 46.84 ? 182 ARG A CB 1 ATOM 1194 C CG . ARG A 1 150 ? 103.316 565.280 94.043 1.00 47.64 ? 182 ARG A CG 1 ATOM 1195 C CD . ARG A 1 150 ? 102.030 565.428 93.280 1.00 57.47 ? 182 ARG A CD 1 ATOM 1196 N NE . ARG A 1 150 ? 102.313 565.966 91.958 1.00 76.01 ? 182 ARG A NE 1 ATOM 1197 C CZ . ARG A 1 150 ? 101.396 566.236 91.038 1.00 94.12 ? 182 ARG A CZ 1 ATOM 1198 N NH1 . ARG A 1 150 ? 100.108 566.016 91.286 1.00 79.20 ? 182 ARG A NH1 1 ATOM 1199 N NH2 . ARG A 1 150 ? 101.758 566.725 89.859 1.00 83.85 ? 182 ARG A NH2 1 ATOM 1200 N N . ALA A 1 151 ? 103.276 563.555 98.186 1.00 62.07 ? 183 ALA A N 1 ATOM 1201 C CA . ALA A 1 151 ? 102.899 562.718 99.355 1.00 64.61 ? 183 ALA A CA 1 ATOM 1202 C C . ALA A 1 151 ? 102.129 561.423 98.992 1.00 73.76 ? 183 ALA A C 1 ATOM 1203 O O . ALA A 1 151 ? 101.020 561.543 98.462 1.00 73.06 ? 183 ALA A O 1 ATOM 1204 C CB . ALA A 1 151 ? 102.090 563.532 100.348 1.00 65.58 ? 183 ALA A CB 1 ATOM 1205 N N . PRO A 1 152 ? 102.690 560.205 99.318 1.00 74.45 ? 184 PRO A N 1 ATOM 1206 C CA . PRO A 1 152 ? 102.034 558.911 98.964 1.00 75.28 ? 184 PRO A CA 1 ATOM 1207 C C . PRO A 1 152 ? 100.581 558.686 99.394 1.00 82.79 ? 184 PRO A C 1 ATOM 1208 O O . PRO A 1 152 ? 100.066 559.381 100.281 1.00 82.80 ? 184 PRO A O 1 ATOM 1209 C CB . PRO A 1 152 ? 102.929 557.858 99.632 1.00 76.77 ? 184 PRO A CB 1 ATOM 1210 C CG . PRO A 1 152 ? 104.242 558.494 99.768 1.00 81.09 ? 184 PRO A CG 1 ATOM 1211 C CD . PRO A 1 152 ? 104.013 559.974 99.942 1.00 76.48 ? 184 PRO A CD 1 ATOM 1212 N N . ARG A 1 153 ? 99.926 557.683 98.753 1.00 81.20 ? 185 ARG A N 1 ATOM 1213 C CA . ARG A 1 153 ? 98.531 557.295 99.011 1.00 81.54 ? 185 ARG A CA 1 ATOM 1214 C C . ARG A 1 153 ? 98.344 555.774 98.934 1.00 86.72 ? 185 ARG A C 1 ATOM 1215 O O . ARG A 1 153 ? 98.890 555.112 98.047 1.00 86.56 ? 185 ARG A O 1 ATOM 1216 C CB . ARG A 1 153 ? 97.582 557.976 98.019 1.00 80.69 ? 185 ARG A CB 1 ATOM 1217 C CG . ARG A 1 153 ? 97.651 559.492 98.004 1.00 83.77 ? 185 ARG A CG 1 ATOM 1218 C CD . ARG A 1 153 ? 97.178 559.988 96.672 1.00 84.29 ? 185 ARG A CD 1 ATOM 1219 N NE . ARG A 1 153 ? 97.277 561.439 96.571 1.00 84.06 ? 185 ARG A NE 1 ATOM 1220 C CZ . ARG A 1 153 ? 96.624 562.166 95.671 1.00 94.23 ? 185 ARG A CZ 1 ATOM 1221 N NH1 . ARG A 1 153 ? 95.827 561.578 94.782 1.00 71.95 ? 185 ARG A NH1 1 ATOM 1222 N NH2 . ARG A 1 153 ? 96.762 563.484 95.650 1.00 82.59 ? 185 ARG A NH2 1 ATOM 1223 N N . GLU A 1 190 ? 96.329 565.747 86.240 1.00 53.28 ? 244 GLU A N 1 ATOM 1224 C CA . GLU A 1 190 ? 95.411 565.047 87.151 1.00 54.01 ? 244 GLU A CA 1 ATOM 1225 C C . GLU A 1 190 ? 94.859 563.705 86.606 1.00 57.79 ? 244 GLU A C 1 ATOM 1226 O O . GLU A 1 190 ? 95.227 562.677 87.168 1.00 58.25 ? 244 GLU A O 1 ATOM 1227 C CB . GLU A 1 190 ? 94.259 565.941 87.614 1.00 55.76 ? 244 GLU A CB 1 ATOM 1228 C CG . GLU A 1 190 ? 94.629 566.960 88.673 1.00 71.73 ? 244 GLU A CG 1 ATOM 1229 C CD . GLU A 1 190 ? 93.713 568.173 88.721 1.00 92.58 ? 244 GLU A CD 1 ATOM 1230 O OE1 . GLU A 1 190 ? 93.138 568.533 87.665 1.00 89.92 ? 244 GLU A OE1 1 ATOM 1231 O OE2 . GLU A 1 190 ? 93.596 568.785 89.809 1.00 73.34 ? 244 GLU A OE2 1 ATOM 1232 N N . PRO A 1 191 ? 93.994 563.642 85.553 1.00 52.56 ? 245 PRO A N 1 ATOM 1233 C CA . PRO A 1 191 ? 93.498 562.318 85.112 1.00 51.12 ? 245 PRO A CA 1 ATOM 1234 C C . PRO A 1 191 ? 94.592 561.271 84.872 1.00 50.53 ? 245 PRO A C 1 ATOM 1235 O O . PRO A 1 191 ? 95.496 561.510 84.079 1.00 49.71 ? 245 PRO A O 1 ATOM 1236 C CB . PRO A 1 191 ? 92.678 562.611 83.852 1.00 52.98 ? 245 PRO A CB 1 ATOM 1237 C CG . PRO A 1 191 ? 92.606 564.054 83.725 1.00 57.84 ? 245 PRO A CG 1 ATOM 1238 C CD . PRO A 1 191 ? 93.404 564.744 84.761 1.00 54.01 ? 245 PRO A CD 1 ATOM 1239 N N . GLY A 1 192 ? 94.523 560.155 85.615 1.00 43.80 ? 246 GLY A N 1 ATOM 1240 C CA . GLY A 1 192 ? 95.469 559.047 85.539 1.00 41.66 ? 246 GLY A CA 1 ATOM 1241 C C . GLY A 1 192 ? 96.855 559.330 86.094 1.00 41.19 ? 246 GLY A C 1 ATOM 1242 O O . GLY A 1 192 ? 97.760 558.526 85.879 1.00 41.04 ? 246 GLY A O 1 ATOM 1243 N N . ALA A 1 193 ? 97.052 560.465 86.805 1.00 33.86 ? 247 ALA A N 1 ATOM 1244 C CA . ALA A 1 193 ? 98.346 560.790 87.400 1.00 31.91 ? 247 ALA A CA 1 ATOM 1245 C C . ALA A 1 193 ? 98.651 559.857 88.565 1.00 34.80 ? 247 ALA A C 1 ATOM 1246 O O . ALA A 1 193 ? 99.815 559.583 88.804 1.00 35.00 ? 247 ALA A O 1 ATOM 1247 C CB . ALA A 1 193 ? 98.391 562.232 87.851 1.00 32.29 ? 247 ALA A CB 1 ATOM 1248 N N . TRP A 1 194 ? 97.616 559.352 89.267 1.00 30.11 ? 248 TRP A N 1 ATOM 1249 C CA . TRP A 1 194 ? 97.744 558.402 90.372 1.00 29.51 ? 248 TRP A CA 1 ATOM 1250 C C . TRP A 1 194 ? 97.255 557.046 89.857 1.00 34.10 ? 248 TRP A C 1 ATOM 1251 O O . TRP A 1 194 ? 97.775 556.611 88.828 1.00 33.53 ? 248 TRP A O 1 ATOM 1252 C CB . TRP A 1 194 ? 97.009 558.930 91.625 1.00 27.59 ? 248 TRP A CB 1 ATOM 1253 C CG . TRP A 1 194 ? 97.685 560.153 92.161 1.00 28.15 ? 248 TRP A CG 1 ATOM 1254 C CD1 . TRP A 1 194 ? 97.494 561.443 91.758 1.00 30.94 ? 248 TRP A CD1 1 ATOM 1255 C CD2 . TRP A 1 194 ? 98.767 560.181 93.098 1.00 27.60 ? 248 TRP A CD2 1 ATOM 1256 N NE1 . TRP A 1 194 ? 98.365 562.278 92.421 1.00 30.13 ? 248 TRP A NE1 1 ATOM 1257 C CE2 . TRP A 1 194 ? 99.167 561.528 93.240 1.00 30.95 ? 248 TRP A CE2 1 ATOM 1258 C CE3 . TRP A 1 194 ? 99.425 559.196 93.850 1.00 28.72 ? 248 TRP A CE3 1 ATOM 1259 C CZ2 . TRP A 1 194 ? 100.177 561.918 94.123 1.00 30.41 ? 248 TRP A CZ2 1 ATOM 1260 C CZ3 . TRP A 1 194 ? 100.435 559.578 94.715 1.00 30.30 ? 248 TRP A CZ3 1 ATOM 1261 C CH2 . TRP A 1 194 ? 100.789 560.925 94.863 1.00 31.00 ? 248 TRP A CH2 1 ATOM 1262 N N . GLU A 1 195 ? 96.235 556.404 90.490 1.00 31.79 ? 249 GLU A N 1 ATOM 1263 C CA . GLU A 1 195 ? 95.650 555.136 89.995 1.00 31.37 ? 249 GLU A CA 1 ATOM 1264 C C . GLU A 1 195 ? 95.289 555.308 88.521 1.00 34.73 ? 249 GLU A C 1 ATOM 1265 O O . GLU A 1 195 ? 94.850 556.388 88.118 1.00 35.29 ? 249 GLU A O 1 ATOM 1266 C CB . GLU A 1 195 ? 94.408 554.712 90.788 1.00 32.61 ? 249 GLU A CB 1 ATOM 1267 C CG . GLU A 1 195 ? 94.672 554.439 92.261 1.00 44.65 ? 249 GLU A CG 1 ATOM 1268 C CD . GLU A 1 195 ? 94.788 555.629 93.206 1.00 65.87 ? 249 GLU A CD 1 ATOM 1269 O OE1 . GLU A 1 195 ? 94.618 556.792 92.771 1.00 51.74 ? 249 GLU A OE1 1 ATOM 1270 O OE2 . GLU A 1 195 ? 95.070 555.386 94.400 1.00 63.48 ? 249 GLU A OE2 1 ATOM 1271 N N . GLU A 1 196 ? 95.532 554.278 87.708 1.00 29.17 ? 250 GLU A N 1 ATOM 1272 C CA . GLU A 1 196 ? 95.381 554.383 86.267 1.00 26.89 ? 250 GLU A CA 1 ATOM 1273 C C . GLU A 1 196 ? 94.974 553.034 85.697 1.00 33.74 ? 250 GLU A C 1 ATOM 1274 O O . GLU A 1 196 ? 95.428 551.998 86.159 1.00 34.09 ? 250 GLU A O 1 ATOM 1275 C CB . GLU A 1 196 ? 96.735 554.859 85.718 1.00 26.67 ? 250 GLU A CB 1 ATOM 1276 C CG . GLU A 1 196 ? 96.763 555.243 84.260 1.00 22.42 ? 250 GLU A CG 1 ATOM 1277 C CD . GLU A 1 196 ? 98.108 555.695 83.723 1.00 29.63 ? 250 GLU A CD 1 ATOM 1278 O OE1 . GLU A 1 196 ? 99.106 555.713 84.476 1.00 17.70 ? 250 GLU A OE1 1 ATOM 1279 O OE2 . GLU A 1 196 ? 98.172 556.006 82.515 1.00 42.45 ? 250 GLU A OE2 1 ATOM 1280 N N . THR A 1 197 ? 94.076 553.030 84.746 1.00 32.88 ? 251 THR A N 1 ATOM 1281 C CA . THR A 1 197 ? 93.652 551.766 84.167 1.00 34.74 ? 251 THR A CA 1 ATOM 1282 C C . THR A 1 197 ? 93.877 551.805 82.678 1.00 38.77 ? 251 THR A C 1 ATOM 1283 O O . THR A 1 197 ? 93.812 552.878 82.053 1.00 38.87 ? 251 THR A O 1 ATOM 1284 C CB . THR A 1 197 ? 92.182 551.425 84.502 1.00 55.44 ? 251 THR A CB 1 ATOM 1285 O OG1 . THR A 1 197 ? 91.331 552.391 83.870 1.00 62.52 ? 251 THR A OG1 1 ATOM 1286 C CG2 . THR A 1 197 ? 91.900 551.361 86.019 1.00 56.25 ? 251 THR A CG2 1 ATOM 1287 N N . PHE A 1 198 ? 94.191 550.638 82.120 1.00 33.49 ? 252 PHE A N 1 ATOM 1288 C CA . PHE A 1 198 ? 94.347 550.444 80.692 1.00 32.38 ? 252 PHE A CA 1 ATOM 1289 C C . PHE A 1 198 ? 93.668 549.129 80.408 1.00 39.77 ? 252 PHE A C 1 ATOM 1290 O O . PHE A 1 198 ? 94.081 548.058 80.931 1.00 39.27 ? 252 PHE A O 1 ATOM 1291 C CB . PHE A 1 198 ? 95.803 550.426 80.267 1.00 32.84 ? 252 PHE A CB 1 ATOM 1292 C CG . PHE A 1 198 ? 95.957 550.206 78.784 1.00 32.14 ? 252 PHE A CG 1 ATOM 1293 C CD1 . PHE A 1 198 ? 95.459 551.132 77.872 1.00 33.35 ? 252 PHE A CD1 1 ATOM 1294 C CD2 . PHE A 1 198 ? 96.578 549.063 78.298 1.00 31.78 ? 252 PHE A CD2 1 ATOM 1295 C CE1 . PHE A 1 198 ? 95.581 550.918 76.506 1.00 32.39 ? 252 PHE A CE1 1 ATOM 1296 C CE2 . PHE A 1 198 ? 96.723 548.865 76.927 1.00 33.03 ? 252 PHE A CE2 1 ATOM 1297 C CZ . PHE A 1 198 ? 96.222 549.792 76.045 1.00 30.37 ? 252 PHE A CZ 1 ATOM 1298 N N . LYS A 1 199 ? 92.614 549.232 79.560 1.00 37.00 ? 253 LYS A N 1 ATOM 1299 C CA A LYS A 1 199 ? 91.728 548.122 79.240 0.50 36.26 ? 253 LYS A CA 1 ATOM 1300 C CA B LYS A 1 199 ? 91.738 548.109 79.241 0.50 36.52 ? 253 LYS A CA 1 ATOM 1301 C C . LYS A 1 199 ? 91.218 547.595 80.598 1.00 41.96 ? 253 LYS A C 1 ATOM 1302 O O . LYS A 1 199 ? 90.614 548.396 81.341 1.00 41.09 ? 253 LYS A O 1 ATOM 1303 C CB A LYS A 1 199 ? 92.390 547.068 78.316 0.50 36.71 ? 253 LYS A CB 1 ATOM 1304 C CB B LYS A 1 199 ? 92.424 547.022 78.359 0.50 37.49 ? 253 LYS A CB 1 ATOM 1305 C CG A LYS A 1 199 ? 92.596 547.587 76.886 0.50 28.89 ? 253 LYS A CG 1 ATOM 1306 C CG B LYS A 1 199 ? 92.934 547.513 76.992 0.50 37.16 ? 253 LYS A CG 1 ATOM 1307 C CD A LYS A 1 199 ? 93.412 546.641 76.020 0.50 25.49 ? 253 LYS A CD 1 ATOM 1308 C CD B LYS A 1 199 ? 91.811 547.912 76.025 0.50 39.63 ? 253 LYS A CD 1 ATOM 1309 C CE A LYS A 1 199 ? 92.556 545.705 75.212 0.50 19.72 ? 253 LYS A CE 1 ATOM 1310 C CE B LYS A 1 199 ? 91.915 549.345 75.536 0.50 43.85 ? 253 LYS A CE 1 ATOM 1311 N NZ A LYS A 1 199 ? 92.090 546.330 73.953 0.50 23.62 ? 253 LYS A NZ 1 ATOM 1312 N NZ B LYS A 1 199 ? 91.659 550.352 76.605 0.50 41.45 ? 253 LYS A NZ 1 ATOM 1313 N N . THR A 1 200 ? 91.505 546.320 80.979 1.00 40.46 ? 254 THR A N 1 ATOM 1314 C CA . THR A 1 200 ? 91.006 545.799 82.260 1.00 41.19 ? 254 THR A CA 1 ATOM 1315 C C . THR A 1 200 ? 92.026 545.825 83.396 1.00 45.05 ? 254 THR A C 1 ATOM 1316 O O . THR A 1 200 ? 91.731 545.345 84.497 1.00 45.69 ? 254 THR A O 1 ATOM 1317 C CB . THR A 1 200 ? 90.442 544.388 82.074 1.00 56.49 ? 254 THR A CB 1 ATOM 1318 O OG1 . THR A 1 200 ? 91.521 543.482 81.846 1.00 61.55 ? 254 THR A OG1 1 ATOM 1319 C CG2 . THR A 1 200 ? 89.450 544.308 80.943 1.00 58.66 ? 254 THR A CG2 1 ATOM 1320 N N . HIS A 1 201 ? 93.219 546.364 83.134 1.00 39.75 ? 255 HIS A N 1 ATOM 1321 C CA . HIS A 1 201 ? 94.306 546.367 84.099 1.00 38.55 ? 255 HIS A CA 1 ATOM 1322 C C . HIS A 1 201 ? 94.443 547.684 84.819 1.00 43.60 ? 255 HIS A C 1 ATOM 1323 O O . HIS A 1 201 ? 94.385 548.748 84.210 1.00 42.60 ? 255 HIS A O 1 ATOM 1324 C CB . HIS A 1 201 ? 95.619 545.957 83.417 1.00 38.44 ? 255 HIS A CB 1 ATOM 1325 C CG . HIS A 1 201 ? 95.540 544.625 82.736 1.00 40.59 ? 255 HIS A CG 1 ATOM 1326 N ND1 . HIS A 1 201 ? 95.363 544.526 81.358 1.00 41.36 ? 255 HIS A ND1 1 ATOM 1327 C CD2 . HIS A 1 201 ? 95.565 543.380 83.270 1.00 41.35 ? 255 HIS A CD2 1 ATOM 1328 C CE1 . HIS A 1 201 ? 95.300 543.231 81.101 1.00 40.65 ? 255 HIS A CE1 1 ATOM 1329 N NE2 . HIS A 1 201 ? 95.418 542.502 82.218 1.00 41.14 ? 255 HIS A NE2 1 ATOM 1330 N N . SER A 1 202 ? 94.616 547.600 86.128 1.00 41.07 ? 256 SER A N 1 ATOM 1331 C CA . SER A 1 202 ? 94.750 548.759 86.989 1.00 40.04 ? 256 SER A CA 1 ATOM 1332 C C . SER A 1 202 ? 96.174 548.815 87.544 1.00 41.20 ? 256 SER A C 1 ATOM 1333 O O . SER A 1 202 ? 96.754 547.777 87.868 1.00 42.11 ? 256 SER A O 1 ATOM 1334 C CB . SER A 1 202 ? 93.729 548.677 88.123 1.00 43.53 ? 256 SER A CB 1 ATOM 1335 O OG . SER A 1 202 ? 93.711 549.867 88.898 1.00 54.57 ? 256 SER A OG 1 ATOM 1336 N N . ASP A 1 203 ? 96.737 550.017 87.607 1.00 34.12 ? 257 ASP A N 1 ATOM 1337 C CA . ASP A 1 203 ? 98.040 550.302 88.170 1.00 32.06 ? 257 ASP A CA 1 ATOM 1338 C C . ASP A 1 203 ? 97.755 551.135 89.411 1.00 33.59 ? 257 ASP A C 1 ATOM 1339 O O . ASP A 1 203 ? 97.273 552.261 89.281 1.00 33.17 ? 257 ASP A O 1 ATOM 1340 C CB . ASP A 1 203 ? 98.900 551.081 87.152 1.00 33.39 ? 257 ASP A CB 1 ATOM 1341 C CG . ASP A 1 203 ? 100.262 551.566 87.661 1.00 35.10 ? 257 ASP A CG 1 ATOM 1342 O OD1 . ASP A 1 203 ? 100.614 551.270 88.838 1.00 36.92 ? 257 ASP A OD1 1 ATOM 1343 O OD2 . ASP A 1 203 ? 100.951 552.279 86.911 1.00 32.03 ? 257 ASP A OD2 1 ATOM 1344 N N . SER A 1 204 ? 98.022 550.594 90.610 1.00 29.84 ? 258 SER A N 1 ATOM 1345 C CA . SER A 1 204 ? 97.760 551.324 91.874 1.00 29.15 ? 258 SER A CA 1 ATOM 1346 C C . SER A 1 204 ? 98.643 552.568 92.069 1.00 35.70 ? 258 SER A C 1 ATOM 1347 O O . SER A 1 204 ? 98.284 553.449 92.867 1.00 36.39 ? 258 SER A O 1 ATOM 1348 C CB . SER A 1 204 ? 97.836 550.405 93.086 1.00 29.14 ? 258 SER A CB 1 ATOM 1349 O OG . SER A 1 204 ? 99.160 549.963 93.302 1.00 34.99 ? 258 SER A OG 1 ATOM 1350 N N . LYS A 1 205 ? 99.795 552.635 91.344 1.00 31.70 ? 259 LYS A N 1 ATOM 1351 C CA . LYS A 1 205 ? 100.675 553.807 91.273 1.00 30.63 ? 259 LYS A CA 1 ATOM 1352 C C . LYS A 1 205 ? 100.832 554.539 92.636 1.00 35.71 ? 259 LYS A C 1 ATOM 1353 O O . LYS A 1 205 ? 100.410 555.685 92.799 1.00 36.29 ? 259 LYS A O 1 ATOM 1354 C CB . LYS A 1 205 ? 100.102 554.729 90.209 1.00 30.99 ? 259 LYS A CB 1 ATOM 1355 C CG . LYS A 1 205 ? 100.927 555.958 89.891 1.00 25.72 ? 259 LYS A CG 1 ATOM 1356 C CD . LYS A 1 205 ? 101.552 555.975 88.506 1.00 23.15 ? 259 LYS A CD 1 ATOM 1357 C CE . LYS A 1 205 ? 100.605 555.757 87.351 1.00 18.86 ? 259 LYS A CE 1 ATOM 1358 N NZ . LYS A 1 205 ? 99.839 556.965 86.994 1.00 26.75 ? 259 LYS A NZ 1 ATOM 1359 N N . PRO A 1 206 ? 101.442 553.870 93.626 1.00 31.83 ? 260 PRO A N 1 ATOM 1360 C CA . PRO A 1 206 ? 101.582 554.490 94.956 1.00 30.81 ? 260 PRO A CA 1 ATOM 1361 C C . PRO A 1 206 ? 102.350 555.806 95.038 1.00 35.03 ? 260 PRO A C 1 ATOM 1362 O O . PRO A 1 206 ? 102.096 556.597 95.955 1.00 34.21 ? 260 PRO A O 1 ATOM 1363 C CB . PRO A 1 206 ? 102.283 553.408 95.774 1.00 32.04 ? 260 PRO A CB 1 ATOM 1364 C CG . PRO A 1 206 ? 102.943 552.526 94.746 1.00 36.88 ? 260 PRO A CG 1 ATOM 1365 C CD . PRO A 1 206 ? 102.009 552.502 93.605 1.00 32.84 ? 260 PRO A CD 1 ATOM 1366 N N . TYR A 1 207 ? 103.297 556.042 94.108 1.00 33.01 ? 261 TYR A N 1 ATOM 1367 C CA . TYR A 1 207 ? 104.125 557.261 94.123 1.00 31.43 ? 261 TYR A CA 1 ATOM 1368 C C . TYR A 1 207 ? 103.638 558.349 93.208 1.00 34.16 ? 261 TYR A C 1 ATOM 1369 O O . TYR A 1 207 ? 104.235 559.421 93.189 1.00 33.22 ? 261 TYR A O 1 ATOM 1370 C CB . TYR A 1 207 ? 105.600 556.949 93.851 1.00 31.91 ? 261 TYR A CB 1 ATOM 1371 C CG . TYR A 1 207 ? 106.075 555.792 94.693 1.00 33.22 ? 261 TYR A CG 1 ATOM 1372 C CD1 . TYR A 1 207 ? 105.963 555.823 96.080 1.00 35.36 ? 261 TYR A CD1 1 ATOM 1373 C CD2 . TYR A 1 207 ? 106.552 554.629 94.102 1.00 33.10 ? 261 TYR A CD2 1 ATOM 1374 C CE1 . TYR A 1 207 ? 106.317 554.725 96.857 1.00 37.05 ? 261 TYR A CE1 1 ATOM 1375 C CE2 . TYR A 1 207 ? 106.926 553.532 94.868 1.00 33.70 ? 261 TYR A CE2 1 ATOM 1376 C CZ . TYR A 1 207 ? 106.813 553.585 96.248 1.00 43.42 ? 261 TYR A CZ 1 ATOM 1377 O OH . TYR A 1 207 ? 107.183 552.505 97.014 1.00 45.11 ? 261 TYR A OH 1 ATOM 1378 N N . GLY A 1 208 ? 102.548 558.099 92.489 1.00 29.92 ? 262 GLY A N 1 ATOM 1379 C CA . GLY A 1 208 ? 101.992 559.088 91.585 1.00 29.46 ? 262 GLY A CA 1 ATOM 1380 C C . GLY A 1 208 ? 102.923 559.526 90.475 1.00 34.88 ? 262 GLY A C 1 ATOM 1381 O O . GLY A 1 208 ? 103.792 558.770 90.068 1.00 35.24 ? 262 GLY A O 1 ATOM 1382 N N . PRO A 1 209 ? 102.781 560.773 89.998 1.00 32.59 ? 263 PRO A N 1 ATOM 1383 C CA . PRO A 1 209 ? 103.599 561.230 88.860 1.00 31.97 ? 263 PRO A CA 1 ATOM 1384 C C . PRO A 1 209 ? 105.045 561.534 89.218 1.00 35.59 ? 263 PRO A C 1 ATOM 1385 O O . PRO A 1 209 ? 105.318 562.368 90.079 1.00 34.82 ? 263 PRO A O 1 ATOM 1386 C CB . PRO A 1 209 ? 102.836 562.459 88.349 1.00 33.50 ? 263 PRO A CB 1 ATOM 1387 C CG . PRO A 1 209 ? 102.099 562.957 89.550 1.00 37.79 ? 263 PRO A CG 1 ATOM 1388 C CD . PRO A 1 209 ? 101.774 561.785 90.396 1.00 33.22 ? 263 PRO A CD 1 ATOM 1389 N N . THR A 1 210 ? 105.978 560.843 88.552 1.00 31.63 ? 264 THR A N 1 ATOM 1390 C CA . THR A 1 210 ? 107.409 560.976 88.829 1.00 30.43 ? 264 THR A CA 1 ATOM 1391 C C . THR A 1 210 ? 108.228 560.998 87.517 1.00 33.68 ? 264 THR A C 1 ATOM 1392 O O . THR A 1 210 ? 109.431 560.702 87.540 1.00 32.64 ? 264 THR A O 1 ATOM 1393 C CB . THR A 1 210 ? 107.905 559.773 89.706 1.00 31.38 ? 264 THR A CB 1 ATOM 1394 O OG1 . THR A 1 210 ? 107.777 558.543 88.970 1.00 25.03 ? 264 THR A OG1 1 ATOM 1395 C CG2 . THR A 1 210 ? 107.175 559.641 91.028 1.00 26.45 ? 264 THR A CG2 1 ATOM 1396 N N . SER A 1 211 ? 107.600 561.324 86.385 1.00 29.22 ? 265 SER A N 1 ATOM 1397 C CA . SER A 1 211 ? 108.323 561.265 85.121 1.00 29.02 ? 265 SER A CA 1 ATOM 1398 C C . SER A 1 211 ? 109.370 562.392 84.951 1.00 34.81 ? 265 SER A C 1 ATOM 1399 O O . SER A 1 211 ? 109.315 563.456 85.594 1.00 34.13 ? 265 SER A O 1 ATOM 1400 C CB . SER A 1 211 ? 107.365 561.181 83.934 1.00 29.88 ? 265 SER A CB 1 ATOM 1401 O OG . SER A 1 211 ? 106.711 562.417 83.708 1.00 35.51 ? 265 SER A OG 1 ATOM 1402 N N . VAL A 1 212 ? 110.372 562.092 84.127 1.00 30.36 ? 266 VAL A N 1 ATOM 1403 C CA . VAL A 1 212 ? 111.492 562.978 83.859 1.00 28.45 ? 266 VAL A CA 1 ATOM 1404 C C . VAL A 1 212 ? 111.700 563.046 82.363 1.00 28.66 ? 266 VAL A C 1 ATOM 1405 O O . VAL A 1 212 ? 111.515 562.060 81.660 1.00 27.41 ? 266 VAL A O 1 ATOM 1406 C CB . VAL A 1 212 ? 112.765 562.478 84.580 1.00 31.55 ? 266 VAL A CB 1 ATOM 1407 C CG1 . VAL A 1 212 ? 112.565 562.440 86.081 1.00 30.57 ? 266 VAL A CG1 1 ATOM 1408 C CG2 . VAL A 1 212 ? 113.223 561.108 84.057 1.00 31.30 ? 266 VAL A CG2 1 ATOM 1409 N N . GLY A 1 213 ? 112.067 564.207 81.887 1.00 24.21 ? 267 GLY A N 1 ATOM 1410 C CA . GLY A 1 213 ? 112.297 564.407 80.469 1.00 23.99 ? 267 GLY A CA 1 ATOM 1411 C C . GLY A 1 213 ? 113.135 565.631 80.213 1.00 27.38 ? 267 GLY A C 1 ATOM 1412 O O . GLY A 1 213 ? 113.183 566.546 81.041 1.00 26.89 ? 267 GLY A O 1 ATOM 1413 N N . LEU A 1 214 ? 113.807 565.631 79.066 1.00 23.47 ? 268 LEU A N 1 ATOM 1414 C CA . LEU A 1 214 ? 114.729 566.667 78.666 1.00 22.95 ? 268 LEU A CA 1 ATOM 1415 C C . LEU A 1 214 ? 114.920 566.598 77.181 1.00 27.05 ? 268 LEU A C 1 ATOM 1416 O O . LEU A 1 214 ? 114.962 565.500 76.604 1.00 27.30 ? 268 LEU A O 1 ATOM 1417 C CB . LEU A 1 214 ? 116.075 566.413 79.374 1.00 22.56 ? 268 LEU A CB 1 ATOM 1418 C CG . LEU A 1 214 ? 117.161 567.474 79.333 1.00 24.72 ? 268 LEU A CG 1 ATOM 1419 C CD1 . LEU A 1 214 ? 116.661 568.830 79.712 1.00 24.25 ? 268 LEU A CD1 1 ATOM 1420 C CD2 . LEU A 1 214 ? 118.264 567.100 80.246 1.00 23.54 ? 268 LEU A CD2 1 ATOM 1421 N N . ASP A 1 215 ? 115.094 567.773 76.566 1.00 22.46 ? 269 ASP A N 1 ATOM 1422 C CA . ASP A 1 215 ? 115.334 567.897 75.129 1.00 21.89 ? 269 ASP A CA 1 ATOM 1423 C C . ASP A 1 215 ? 116.779 568.307 74.836 1.00 21.66 ? 269 ASP A C 1 ATOM 1424 O O . ASP A 1 215 ? 117.437 568.943 75.667 1.00 19.87 ? 269 ASP A O 1 ATOM 1425 C CB . ASP A 1 215 ? 114.356 568.905 74.499 1.00 24.17 ? 269 ASP A CB 1 ATOM 1426 C CG . ASP A 1 215 ? 114.590 570.332 74.999 1.00 34.43 ? 269 ASP A CG 1 ATOM 1427 O OD1 . ASP A 1 215 ? 114.395 570.582 76.219 1.00 34.00 ? 269 ASP A OD1 1 ATOM 1428 O OD2 . ASP A 1 215 ? 115.087 571.156 74.210 1.00 40.81 ? 269 ASP A OD2 1 ATOM 1429 N N . PHE A 1 216 ? 117.234 567.951 73.629 1.00 16.18 ? 270 PHE A N 1 ATOM 1430 C CA . PHE A 1 216 ? 118.563 568.174 73.098 1.00 15.84 ? 270 PHE A CA 1 ATOM 1431 C C . PHE A 1 216 ? 118.415 568.655 71.657 1.00 20.19 ? 270 PHE A C 1 ATOM 1432 O O . PHE A 1 216 ? 117.550 568.158 70.927 1.00 16.61 ? 270 PHE A O 1 ATOM 1433 C CB . PHE A 1 216 ? 119.390 566.867 73.110 1.00 17.78 ? 270 PHE A CB 1 ATOM 1434 C CG . PHE A 1 216 ? 119.497 566.256 74.477 1.00 19.40 ? 270 PHE A CG 1 ATOM 1435 C CD1 . PHE A 1 216 ? 118.505 565.406 74.955 1.00 21.49 ? 270 PHE A CD1 1 ATOM 1436 C CD2 . PHE A 1 216 ? 120.552 566.581 75.314 1.00 21.29 ? 270 PHE A CD2 1 ATOM 1437 C CE1 . PHE A 1 216 ? 118.538 564.948 76.264 1.00 23.36 ? 270 PHE A CE1 1 ATOM 1438 C CE2 . PHE A 1 216 ? 120.611 566.083 76.602 1.00 23.83 ? 270 PHE A CE2 1 ATOM 1439 C CZ . PHE A 1 216 ? 119.596 565.282 77.080 1.00 22.55 ? 270 PHE A CZ 1 ATOM 1440 N N . SER A 1 217 ? 119.284 569.616 71.259 1.00 17.56 ? 271 SER A N 1 ATOM 1441 C CA . SER A 1 217 ? 119.312 570.219 69.943 1.00 16.89 ? 271 SER A CA 1 ATOM 1442 C C . SER A 1 217 ? 120.630 569.919 69.277 1.00 22.69 ? 271 SER A C 1 ATOM 1443 O O . SER A 1 217 ? 121.689 570.056 69.882 1.00 20.67 ? 271 SER A O 1 ATOM 1444 C CB . SER A 1 217 ? 119.070 571.721 70.025 1.00 19.20 ? 271 SER A CB 1 ATOM 1445 O OG . SER A 1 217 ? 117.824 571.943 70.650 1.00 28.12 ? 271 SER A OG 1 ATOM 1446 N N . LEU A 1 218 ? 120.547 569.512 68.014 1.00 22.83 ? 272 LEU A N 1 ATOM 1447 C CA . LEU A 1 218 ? 121.683 569.050 67.247 1.00 24.13 ? 272 LEU A CA 1 ATOM 1448 C C . LEU A 1 218 ? 121.819 569.860 65.988 1.00 31.44 ? 272 LEU A C 1 ATOM 1449 O O . LEU A 1 218 ? 121.358 569.416 64.934 1.00 31.57 ? 272 LEU A O 1 ATOM 1450 C CB . LEU A 1 218 ? 121.484 567.549 66.924 1.00 24.41 ? 272 LEU A CB 1 ATOM 1451 C CG . LEU A 1 218 ? 121.211 566.632 68.118 1.00 29.00 ? 272 LEU A CG 1 ATOM 1452 C CD1 . LEU A 1 218 ? 120.748 565.275 67.688 1.00 28.78 ? 272 LEU A CD1 1 ATOM 1453 C CD2 . LEU A 1 218 ? 122.436 566.525 68.992 1.00 33.09 ? 272 LEU A CD2 1 ATOM 1454 N N . PRO A 1 219 ? 122.451 571.061 66.096 1.00 29.41 ? 273 PRO A N 1 ATOM 1455 C CA . PRO A 1 219 ? 122.646 571.926 64.916 1.00 29.31 ? 273 PRO A CA 1 ATOM 1456 C C . PRO A 1 219 ? 123.503 571.267 63.842 1.00 33.60 ? 273 PRO A C 1 ATOM 1457 O O . PRO A 1 219 ? 124.533 570.650 64.156 1.00 33.57 ? 273 PRO A O 1 ATOM 1458 C CB . PRO A 1 219 ? 123.351 573.152 65.507 1.00 31.06 ? 273 PRO A CB 1 ATOM 1459 C CG . PRO A 1 219 ? 123.958 572.684 66.783 1.00 34.37 ? 273 PRO A CG 1 ATOM 1460 C CD . PRO A 1 219 ? 123.035 571.668 67.309 1.00 29.79 ? 273 PRO A CD 1 ATOM 1461 N N . GLY A 1 220 ? 123.063 571.374 62.594 1.00 30.10 ? 274 GLY A N 1 ATOM 1462 C CA . GLY A 1 220 ? 123.765 570.751 61.474 1.00 29.89 ? 274 GLY A CA 1 ATOM 1463 C C . GLY A 1 220 ? 123.452 569.279 61.260 1.00 32.95 ? 274 GLY A C 1 ATOM 1464 O O . GLY A 1 220 ? 123.912 568.704 60.271 1.00 33.06 ? 274 GLY A O 1 ATOM 1465 N N . MET A 1 221 ? 122.610 568.675 62.129 1.00 26.55 ? 275 MET A N 1 ATOM 1466 C CA . MET A 1 221 ? 122.260 567.266 62.021 1.00 25.99 ? 275 MET A CA 1 ATOM 1467 C C . MET A 1 221 ? 120.882 567.086 61.436 1.00 33.04 ? 275 MET A C 1 ATOM 1468 O O . MET A 1 221 ? 119.930 567.627 61.980 1.00 34.47 ? 275 MET A O 1 ATOM 1469 C CB . MET A 1 221 ? 122.335 566.577 63.401 1.00 27.34 ? 275 MET A CB 1 ATOM 1470 C CG . MET A 1 221 ? 123.722 566.556 64.010 1.00 29.46 ? 275 MET A CG 1 ATOM 1471 S SD . MET A 1 221 ? 124.852 565.551 63.056 1.00 32.22 ? 275 MET A SD 1 ATOM 1472 C CE . MET A 1 221 ? 126.239 565.461 64.156 1.00 28.31 ? 275 MET A CE 1 ATOM 1473 N N . GLU A 1 222 ? 120.763 566.336 60.343 1.00 29.32 ? 276 GLU A N 1 ATOM 1474 C CA . GLU A 1 222 ? 119.475 566.044 59.703 1.00 29.27 ? 276 GLU A CA 1 ATOM 1475 C C . GLU A 1 222 ? 119.171 564.551 59.714 1.00 33.76 ? 276 GLU A C 1 ATOM 1476 O O . GLU A 1 222 ? 118.085 564.155 59.280 1.00 33.36 ? 276 GLU A O 1 ATOM 1477 C CB . GLU A 1 222 ? 119.494 566.460 58.238 1.00 30.67 ? 276 GLU A CB 1 ATOM 1478 C CG . GLU A 1 222 ? 119.678 567.934 57.987 1.00 46.40 ? 276 GLU A CG 1 ATOM 1479 C CD . GLU A 1 222 ? 119.502 568.285 56.524 1.00 79.32 ? 276 GLU A CD 1 ATOM 1480 O OE1 . GLU A 1 222 ? 120.517 568.581 55.852 1.00 78.48 ? 276 GLU A OE1 1 ATOM 1481 O OE2 . GLU A 1 222 ? 118.350 568.227 56.040 1.00 77.98 ? 276 GLU A OE2 1 ATOM 1482 N N . HIS A 1 223 ? 120.141 563.719 60.128 1.00 29.06 ? 277 HIS A N 1 ATOM 1483 C CA . HIS A 1 223 ? 119.995 562.274 60.096 1.00 27.98 ? 277 HIS A CA 1 ATOM 1484 C C . HIS A 1 223 ? 120.284 561.702 61.455 1.00 30.35 ? 277 HIS A C 1 ATOM 1485 O O . HIS A 1 223 ? 121.377 561.925 61.995 1.00 29.41 ? 277 HIS A O 1 ATOM 1486 C CB . HIS A 1 223 ? 120.975 561.694 59.064 1.00 28.91 ? 277 HIS A CB 1 ATOM 1487 C CG . HIS A 1 223 ? 120.671 562.124 57.657 1.00 32.33 ? 277 HIS A CG 1 ATOM 1488 N ND1 . HIS A 1 223 ? 121.054 563.367 57.180 1.00 34.12 ? 277 HIS A ND1 1 ATOM 1489 C CD2 . HIS A 1 223 ? 119.995 561.480 56.682 1.00 33.28 ? 277 HIS A CD2 1 ATOM 1490 C CE1 . HIS A 1 223 ? 120.617 563.431 55.936 1.00 32.75 ? 277 HIS A CE1 1 ATOM 1491 N NE2 . HIS A 1 223 ? 119.960 562.330 55.599 1.00 33.22 ? 277 HIS A NE2 1 ATOM 1492 N N . VAL A 1 224 ? 119.296 560.993 62.034 1.00 25.65 ? 278 VAL A N 1 ATOM 1493 C CA . VAL A 1 224 ? 119.451 560.364 63.347 1.00 23.99 ? 278 VAL A CA 1 ATOM 1494 C C . VAL A 1 224 ? 119.050 558.908 63.260 1.00 27.11 ? 278 VAL A C 1 ATOM 1495 O O . VAL A 1 224 ? 118.255 558.523 62.394 1.00 28.36 ? 278 VAL A O 1 ATOM 1496 C CB . VAL A 1 224 ? 118.823 561.092 64.545 1.00 25.74 ? 278 VAL A CB 1 ATOM 1497 C CG1 . VAL A 1 224 ? 119.407 562.494 64.726 1.00 25.12 ? 278 VAL A CG1 1 ATOM 1498 C CG2 . VAL A 1 224 ? 117.320 561.138 64.435 1.00 24.99 ? 278 VAL A CG2 1 ATOM 1499 N N . TYR A 1 225 ? 119.681 558.096 64.098 1.00 20.47 ? 279 TYR A N 1 ATOM 1500 C CA . TYR A 1 225 ? 119.599 556.648 64.065 1.00 19.70 ? 279 TYR A CA 1 ATOM 1501 C C . TYR A 1 225 ? 119.592 556.029 65.451 1.00 24.36 ? 279 TYR A C 1 ATOM 1502 O O . TYR A 1 225 ? 120.054 556.633 66.412 1.00 21.99 ? 279 TYR A O 1 ATOM 1503 C CB . TYR A 1 225 ? 120.852 556.094 63.347 1.00 19.93 ? 279 TYR A CB 1 ATOM 1504 C CG . TYR A 1 225 ? 121.216 556.779 62.056 1.00 22.26 ? 279 TYR A CG 1 ATOM 1505 C CD1 . TYR A 1 225 ? 122.024 557.914 62.049 1.00 23.98 ? 279 TYR A CD1 1 ATOM 1506 C CD2 . TYR A 1 225 ? 120.806 556.259 60.828 1.00 23.48 ? 279 TYR A CD2 1 ATOM 1507 C CE1 . TYR A 1 225 ? 122.346 558.561 60.860 1.00 23.95 ? 279 TYR A CE1 1 ATOM 1508 C CE2 . TYR A 1 225 ? 121.136 556.891 59.630 1.00 24.47 ? 279 TYR A CE2 1 ATOM 1509 C CZ . TYR A 1 225 ? 121.897 558.048 59.653 1.00 28.13 ? 279 TYR A CZ 1 ATOM 1510 O OH . TYR A 1 225 ? 122.246 558.660 58.477 1.00 26.07 ? 279 TYR A OH 1 ATOM 1511 N N . GLY A 1 226 ? 119.186 554.767 65.502 1.00 23.20 ? 280 GLY A N 1 ATOM 1512 C CA . GLY A 1 226 ? 119.261 553.976 66.707 1.00 22.75 ? 280 GLY A CA 1 ATOM 1513 C C . GLY A 1 226 ? 117.960 553.759 67.406 1.00 26.78 ? 280 GLY A C 1 ATOM 1514 O O . GLY A 1 226 ? 116.980 553.395 66.769 1.00 25.96 ? 280 GLY A O 1 ATOM 1515 N N . ILE A 1 227 ? 117.970 553.931 68.746 1.00 23.84 ? 281 ILE A N 1 ATOM 1516 C CA . ILE A 1 227 ? 116.862 553.629 69.646 1.00 22.40 ? 281 ILE A CA 1 ATOM 1517 C C . ILE A 1 227 ? 116.066 552.399 69.204 1.00 26.05 ? 281 ILE A C 1 ATOM 1518 O O . ILE A 1 227 ? 114.835 552.461 69.121 1.00 25.75 ? 281 ILE A O 1 ATOM 1519 C CB . ILE A 1 227 ? 115.962 554.830 69.961 1.00 24.92 ? 281 ILE A CB 1 ATOM 1520 C CG1 . ILE A 1 227 ? 115.395 555.495 68.707 1.00 24.51 ? 281 ILE A CG1 1 ATOM 1521 C CG2 . ILE A 1 227 ? 116.760 555.824 70.780 1.00 25.16 ? 281 ILE A CG2 1 ATOM 1522 C CD1 . ILE A 1 227 ? 114.361 556.539 68.969 1.00 21.97 ? 281 ILE A CD1 1 ATOM 1523 N N . PRO A 1 228 ? 116.731 551.238 68.949 1.00 22.15 ? 282 PRO A N 1 ATOM 1524 C CA . PRO A 1 228 ? 115.960 550.026 68.638 1.00 20.92 ? 282 PRO A CA 1 ATOM 1525 C C . PRO A 1 228 ? 115.156 549.619 69.896 1.00 24.08 ? 282 PRO A C 1 ATOM 1526 O O . PRO A 1 228 ? 115.482 550.097 70.981 1.00 26.06 ? 282 PRO A O 1 ATOM 1527 C CB . PRO A 1 228 ? 117.054 549.021 68.296 1.00 22.22 ? 282 PRO A CB 1 ATOM 1528 C CG . PRO A 1 228 ? 118.198 549.431 69.104 1.00 25.37 ? 282 PRO A CG 1 ATOM 1529 C CD . PRO A 1 228 ? 118.172 550.919 69.076 1.00 22.17 ? 282 PRO A CD 1 ATOM 1530 N N . GLU A 1 229 ? 114.113 548.790 69.803 1.00 17.78 ? 283 GLU A N 1 ATOM 1531 C CA . GLU A 1 229 ? 113.741 548.047 68.628 1.00 17.87 ? 283 GLU A CA 1 ATOM 1532 C C . GLU A 1 229 ? 112.426 548.498 68.019 1.00 25.85 ? 283 GLU A C 1 ATOM 1533 O O . GLU A 1 229 ? 111.395 548.468 68.697 1.00 28.02 ? 283 GLU A O 1 ATOM 1534 C CB . GLU A 1 229 ? 113.731 546.550 68.978 1.00 17.63 ? 283 GLU A CB 1 ATOM 1535 C CG . GLU A 1 229 ? 113.525 545.649 67.776 1.00 16.51 ? 283 GLU A CG 1 ATOM 1536 C CD . GLU A 1 229 ? 113.653 544.176 68.104 1.00 31.32 ? 283 GLU A CD 1 ATOM 1537 O OE1 . GLU A 1 229 ? 114.095 543.420 67.213 1.00 36.95 ? 283 GLU A OE1 1 ATOM 1538 O OE2 . GLU A 1 229 ? 113.377 543.780 69.257 1.00 13.75 ? 283 GLU A OE2 1 ATOM 1539 N N . HIS A 1 230 ? 112.463 548.887 66.732 1.00 20.95 ? 284 HIS A N 1 ATOM 1540 C CA . HIS A 1 230 ? 111.274 549.246 65.970 1.00 21.15 ? 284 HIS A CA 1 ATOM 1541 C C . HIS A 1 230 ? 111.395 548.630 64.604 1.00 27.63 ? 284 HIS A C 1 ATOM 1542 O O . HIS A 1 230 ? 112.495 548.542 64.052 1.00 26.62 ? 284 HIS A O 1 ATOM 1543 C CB . HIS A 1 230 ? 111.134 550.778 65.832 1.00 21.40 ? 284 HIS A CB 1 ATOM 1544 C CG . HIS A 1 230 ? 111.167 551.460 67.150 1.00 23.96 ? 284 HIS A CG 1 ATOM 1545 N ND1 . HIS A 1 230 ? 112.331 551.997 67.654 1.00 24.63 ? 284 HIS A ND1 1 ATOM 1546 C CD2 . HIS A 1 230 ? 110.209 551.531 68.097 1.00 25.45 ? 284 HIS A CD2 1 ATOM 1547 C CE1 . HIS A 1 230 ? 112.040 552.399 68.871 1.00 23.90 ? 284 HIS A CE1 1 ATOM 1548 N NE2 . HIS A 1 230 ? 110.769 552.164 69.172 1.00 24.45 ? 284 HIS A NE2 1 ATOM 1549 N N . ALA A 1 231 ? 110.263 548.203 64.038 1.00 25.91 ? 285 ALA A N 1 ATOM 1550 C CA . ALA A 1 231 ? 110.235 547.689 62.672 1.00 24.10 ? 285 ALA A CA 1 ATOM 1551 C C . ALA A 1 231 ? 110.034 548.932 61.820 1.00 27.88 ? 285 ALA A C 1 ATOM 1552 O O . ALA A 1 231 ? 108.941 549.272 61.373 1.00 27.85 ? 285 ALA A O 1 ATOM 1553 C CB . ALA A 1 231 ? 109.110 546.676 62.490 1.00 24.22 ? 285 ALA A CB 1 ATOM 1554 N N . ASP A 1 232 ? 111.113 549.674 61.679 1.00 24.52 ? 286 ASP A N 1 ATOM 1555 C CA . ASP A 1 232 ? 111.119 550.928 60.964 1.00 22.27 ? 286 ASP A CA 1 ATOM 1556 C C . ASP A 1 232 ? 112.436 551.128 60.260 1.00 24.44 ? 286 ASP A C 1 ATOM 1557 O O . ASP A 1 232 ? 113.387 550.343 60.419 1.00 23.36 ? 286 ASP A O 1 ATOM 1558 C CB . ASP A 1 232 ? 110.818 552.081 61.937 1.00 23.14 ? 286 ASP A CB 1 ATOM 1559 C CG . ASP A 1 232 ? 110.094 553.263 61.296 1.00 28.27 ? 286 ASP A CG 1 ATOM 1560 O OD1 . ASP A 1 232 ? 109.804 553.200 60.081 1.00 28.83 ? 286 ASP A OD1 1 ATOM 1561 O OD2 . ASP A 1 232 ? 109.839 554.254 62.002 1.00 30.53 ? 286 ASP A OD2 1 ATOM 1562 N N . SER A 1 233 ? 112.480 552.192 59.488 1.00 20.61 ? 287 SER A N 1 ATOM 1563 C CA . SER A 1 233 ? 113.616 552.603 58.703 1.00 20.13 ? 287 SER A CA 1 ATOM 1564 C C . SER A 1 233 ? 114.862 552.903 59.555 1.00 24.67 ? 287 SER A C 1 ATOM 1565 O O . SER A 1 233 ? 114.768 553.310 60.727 1.00 25.62 ? 287 SER A O 1 ATOM 1566 C CB . SER A 1 233 ? 113.224 553.812 57.866 1.00 24.39 ? 287 SER A CB 1 ATOM 1567 O OG . SER A 1 233 ? 112.816 554.865 58.731 1.00 34.97 ? 287 SER A OG 1 ATOM 1568 N N . LEU A 1 234 ? 116.042 552.676 58.950 1.00 21.66 ? 288 LEU A N 1 ATOM 1569 C CA . LEU A 1 234 ? 117.336 552.948 59.594 1.00 21.56 ? 288 LEU A CA 1 ATOM 1570 C C . LEU A 1 234 ? 117.463 554.420 59.988 1.00 25.11 ? 288 LEU A C 1 ATOM 1571 O O . LEU A 1 234 ? 117.824 554.739 61.125 1.00 25.17 ? 288 LEU A O 1 ATOM 1572 C CB . LEU A 1 234 ? 118.469 552.527 58.676 1.00 22.01 ? 288 LEU A CB 1 ATOM 1573 C CG . LEU A 1 234 ? 119.892 552.912 59.050 1.00 27.81 ? 288 LEU A CG 1 ATOM 1574 C CD1 . LEU A 1 234 ? 120.313 552.327 60.424 1.00 28.98 ? 288 LEU A CD1 1 ATOM 1575 C CD2 . LEU A 1 234 ? 120.818 552.464 57.977 1.00 30.94 ? 288 LEU A CD2 1 ATOM 1576 N N . ARG A 1 235 ? 117.167 555.312 59.049 1.00 20.19 ? 289 ARG A N 1 ATOM 1577 C CA . ARG A 1 235 ? 117.116 556.733 59.338 1.00 20.16 ? 289 ARG A CA 1 ATOM 1578 C C . ARG A 1 235 ? 115.803 556.973 60.067 1.00 24.73 ? 289 ARG A C 1 ATOM 1579 O O . ARG A 1 235 ? 114.732 556.711 59.524 1.00 23.88 ? 289 ARG A O 1 ATOM 1580 C CB . ARG A 1 235 ? 117.171 557.585 58.055 1.00 17.34 ? 289 ARG A CB 1 ATOM 1581 C CG . ARG A 1 235 ? 117.212 559.057 58.386 1.00 27.84 ? 289 ARG A CG 1 ATOM 1582 C CD . ARG A 1 235 ? 116.642 559.865 57.260 1.00 39.84 ? 289 ARG A CD 1 ATOM 1583 N NE . ARG A 1 235 ? 116.800 561.301 57.500 1.00 35.81 ? 289 ARG A NE 1 ATOM 1584 C CZ . ARG A 1 235 ? 116.756 562.207 56.535 1.00 43.79 ? 289 ARG A CZ 1 ATOM 1585 N NH1 . ARG A 1 235 ? 116.575 561.835 55.274 1.00 30.57 ? 289 ARG A NH1 1 ATOM 1586 N NH2 . ARG A 1 235 ? 116.922 563.489 56.817 1.00 27.72 ? 289 ARG A NH2 1 ATOM 1587 N N . LEU A 1 236 ? 115.872 557.442 61.294 1.00 21.84 ? 290 LEU A N 1 ATOM 1588 C CA . LEU A 1 236 ? 114.633 557.666 62.039 1.00 21.92 ? 290 LEU A CA 1 ATOM 1589 C C . LEU A 1 236 ? 113.833 558.843 61.505 1.00 29.35 ? 290 LEU A C 1 ATOM 1590 O O . LEU A 1 236 ? 114.390 559.862 61.068 1.00 29.12 ? 290 LEU A O 1 ATOM 1591 C CB . LEU A 1 236 ? 114.929 557.897 63.523 1.00 21.62 ? 290 LEU A CB 1 ATOM 1592 C CG . LEU A 1 236 ? 115.614 556.757 64.266 1.00 24.00 ? 290 LEU A CG 1 ATOM 1593 C CD1 . LEU A 1 236 ? 116.177 557.264 65.558 1.00 23.27 ? 290 LEU A CD1 1 ATOM 1594 C CD2 . LEU A 1 236 ? 114.674 555.601 64.482 1.00 22.20 ? 290 LEU A CD2 1 ATOM 1595 N N . LYS A 1 237 ? 112.513 558.702 61.582 1.00 27.58 ? 291 LYS A N 1 ATOM 1596 C CA . LYS A 1 237 ? 111.562 559.698 61.115 1.00 27.02 ? 291 LYS A CA 1 ATOM 1597 C C . LYS A 1 237 ? 111.215 560.714 62.192 1.00 30.33 ? 291 LYS A C 1 ATOM 1598 O O . LYS A 1 237 ? 111.245 560.409 63.403 1.00 30.87 ? 291 LYS A O 1 ATOM 1599 C CB . LYS A 1 237 ? 110.271 558.995 60.666 1.00 28.36 ? 291 LYS A CB 1 ATOM 1600 C CG . LYS A 1 237 ? 110.447 558.108 59.449 1.00 28.93 ? 291 LYS A CG 1 ATOM 1601 C CD . LYS A 1 237 ? 109.187 557.340 59.220 1.00 30.57 ? 291 LYS A CD 1 ATOM 1602 C CE . LYS A 1 237 ? 109.237 556.515 57.975 1.00 28.20 ? 291 LYS A CE 1 ATOM 1603 N NZ . LYS A 1 237 ? 109.952 555.264 58.208 1.00 39.38 ? 291 LYS A NZ 1 ATOM 1604 N N . VAL A 1 238 ? 110.812 561.900 61.740 1.00 25.03 ? 292 VAL A N 1 ATOM 1605 C CA . VAL A 1 238 ? 110.293 562.964 62.591 1.00 24.43 ? 292 VAL A CA 1 ATOM 1606 C C . VAL A 1 238 ? 108.942 562.406 63.186 1.00 32.76 ? 292 VAL A C 1 ATOM 1607 O O . VAL A 1 238 ? 108.214 561.648 62.526 1.00 33.90 ? 292 VAL A O 1 ATOM 1608 C CB . VAL A 1 238 ? 110.203 564.277 61.759 1.00 26.47 ? 292 VAL A CB 1 ATOM 1609 C CG1 . VAL A 1 238 ? 109.096 565.202 62.213 1.00 27.24 ? 292 VAL A CG1 1 ATOM 1610 C CG2 . VAL A 1 238 ? 111.531 565.005 61.771 1.00 25.56 ? 292 VAL A CG2 1 ATOM 1611 N N . THR A 1 239 ? 108.699 562.674 64.463 1.00 30.19 ? 293 THR A N 1 ATOM 1612 C CA . THR A 1 239 ? 107.533 562.152 65.180 1.00 30.10 ? 293 THR A CA 1 ATOM 1613 C C . THR A 1 239 ? 106.411 563.171 65.325 1.00 35.35 ? 293 THR A C 1 ATOM 1614 O O . THR A 1 239 ? 105.342 562.801 65.759 1.00 33.42 ? 293 THR A O 1 ATOM 1615 C CB . THR A 1 239 ? 107.969 561.617 66.555 1.00 28.97 ? 293 THR A CB 1 ATOM 1616 O OG1 . THR A 1 239 ? 108.470 562.714 67.304 1.00 24.24 ? 293 THR A OG1 1 ATOM 1617 C CG2 . THR A 1 239 ? 109.045 560.552 66.455 1.00 22.52 ? 293 THR A CG2 1 ATOM 1618 N N . GLU A 1 240 ? 106.675 564.447 64.999 1.00 36.53 ? 294 GLU A N 1 ATOM 1619 C CA . GLU A 1 240 ? 105.762 565.610 65.050 1.00 38.21 ? 294 GLU A CA 1 ATOM 1620 C C . GLU A 1 240 ? 104.266 565.326 64.777 1.00 42.71 ? 294 GLU A C 1 ATOM 1621 O O . GLU A 1 240 ? 103.399 565.631 65.618 1.00 44.70 ? 294 GLU A O 1 ATOM 1622 C CB . GLU A 1 240 ? 106.245 566.696 64.061 1.00 39.96 ? 294 GLU A CB 1 ATOM 1623 C CG . GLU A 1 240 ? 107.261 567.669 64.629 1.00 52.55 ? 294 GLU A CG 1 ATOM 1624 C CD . GLU A 1 240 ? 107.881 568.611 63.613 1.00 78.24 ? 294 GLU A CD 1 ATOM 1625 O OE1 . GLU A 1 240 ? 109.089 568.467 63.299 1.00 58.75 ? 294 GLU A OE1 1 ATOM 1626 O OE2 . GLU A 1 240 ? 107.151 569.511 63.140 1.00 83.97 ? 294 GLU A OE2 1 ATOM 1627 N N . GLY A 1 241 ? 103.976 564.779 63.605 1.00 36.43 ? 295 GLY A N 1 ATOM 1628 C CA . GLY A 1 241 ? 102.597 564.503 63.217 1.00 35.80 ? 295 GLY A CA 1 ATOM 1629 C C . GLY A 1 241 ? 101.973 563.234 63.765 1.00 38.54 ? 295 GLY A C 1 ATOM 1630 O O . GLY A 1 241 ? 100.816 562.945 63.454 1.00 38.21 ? 295 GLY A O 1 ATOM 1631 N N . GLY A 1 242 ? 102.724 562.454 64.545 1.00 32.88 ? 296 GLY A N 1 ATOM 1632 C CA . GLY A 1 242 ? 102.220 561.181 65.035 1.00 31.05 ? 296 GLY A CA 1 ATOM 1633 C C . GLY A 1 242 ? 102.708 560.810 66.404 1.00 32.01 ? 296 GLY A C 1 ATOM 1634 O O . GLY A 1 242 ? 102.704 561.626 67.318 1.00 32.99 ? 296 GLY A O 1 ATOM 1635 N N . GLU A 1 243 ? 103.098 559.566 66.548 1.00 26.79 ? 297 GLU A N 1 ATOM 1636 C CA . GLU A 1 243 ? 103.560 559.000 67.796 1.00 25.74 ? 297 GLU A CA 1 ATOM 1637 C C . GLU A 1 243 ? 105.062 559.153 68.004 1.00 30.98 ? 297 GLU A C 1 ATOM 1638 O O . GLU A 1 243 ? 105.833 559.080 67.027 1.00 32.01 ? 297 GLU A O 1 ATOM 1639 C CB . GLU A 1 243 ? 103.195 557.513 67.829 1.00 25.98 ? 297 GLU A CB 1 ATOM 1640 C CG . GLU A 1 243 ? 101.722 557.276 68.022 1.00 25.37 ? 297 GLU A CG 1 ATOM 1641 C CD . GLU A 1 243 ? 101.255 557.628 69.415 1.00 36.08 ? 297 GLU A CD 1 ATOM 1642 O OE1 . GLU A 1 243 ? 101.631 556.911 70.367 1.00 20.28 ? 297 GLU A OE1 1 ATOM 1643 O OE2 . GLU A 1 243 ? 100.536 558.639 69.561 1.00 35.89 ? 297 GLU A OE2 1 ATOM 1644 N N . PRO A 1 244 ? 105.506 559.344 69.266 1.00 26.54 ? 298 PRO A N 1 ATOM 1645 C CA . PRO A 1 244 ? 106.955 559.303 69.527 1.00 26.66 ? 298 PRO A CA 1 ATOM 1646 C C . PRO A 1 244 ? 107.430 557.845 69.402 1.00 32.39 ? 298 PRO A C 1 ATOM 1647 O O . PRO A 1 244 ? 106.614 556.915 69.465 1.00 32.66 ? 298 PRO A O 1 ATOM 1648 C CB . PRO A 1 244 ? 107.084 559.719 71.007 1.00 27.78 ? 298 PRO A CB 1 ATOM 1649 C CG . PRO A 1 244 ? 105.725 560.088 71.471 1.00 32.44 ? 298 PRO A CG 1 ATOM 1650 C CD . PRO A 1 244 ? 104.737 559.450 70.523 1.00 28.58 ? 298 PRO A CD 1 ATOM 1651 N N . TYR A 1 245 ? 108.746 557.638 69.235 1.00 28.05 ? 299 TYR A N 1 ATOM 1652 C CA . TYR A 1 245 ? 109.310 556.302 69.277 1.00 26.91 ? 299 TYR A CA 1 ATOM 1653 C C . TYR A 1 245 ? 109.205 555.813 70.724 1.00 29.75 ? 299 TYR A C 1 ATOM 1654 O O . TYR A 1 245 ? 109.498 556.560 71.655 1.00 29.54 ? 299 TYR A O 1 ATOM 1655 C CB . TYR A 1 245 ? 110.768 556.301 68.808 1.00 27.56 ? 299 TYR A CB 1 ATOM 1656 C CG . TYR A 1 245 ? 110.874 556.365 67.304 1.00 28.09 ? 299 TYR A CG 1 ATOM 1657 C CD1 . TYR A 1 245 ? 110.680 555.231 66.524 1.00 29.05 ? 299 TYR A CD1 1 ATOM 1658 C CD2 . TYR A 1 245 ? 111.077 557.575 66.653 1.00 28.97 ? 299 TYR A CD2 1 ATOM 1659 C CE1 . TYR A 1 245 ? 110.767 555.285 65.136 1.00 27.09 ? 299 TYR A CE1 1 ATOM 1660 C CE2 . TYR A 1 245 ? 111.123 557.649 65.261 1.00 29.45 ? 299 TYR A CE2 1 ATOM 1661 C CZ . TYR A 1 245 ? 110.979 556.499 64.507 1.00 31.55 ? 299 TYR A CZ 1 ATOM 1662 O OH . TYR A 1 245 ? 111.048 556.570 63.134 1.00 29.90 ? 299 TYR A OH 1 ATOM 1663 N N . ARG A 1 246 ? 108.733 554.590 70.914 1.00 23.90 ? 300 ARG A N 1 ATOM 1664 C CA . ARG A 1 246 ? 108.548 554.060 72.246 1.00 22.61 ? 300 ARG A CA 1 ATOM 1665 C C . ARG A 1 246 ? 109.593 553.003 72.557 1.00 25.30 ? 300 ARG A C 1 ATOM 1666 O O . ARG A 1 246 ? 109.840 552.122 71.734 1.00 24.96 ? 300 ARG A O 1 ATOM 1667 C CB . ARG A 1 246 ? 107.132 553.471 72.361 1.00 19.37 ? 300 ARG A CB 1 ATOM 1668 C CG . ARG A 1 246 ? 106.729 553.197 73.786 1.00 24.95 ? 300 ARG A CG 1 ATOM 1669 C CD . ARG A 1 246 ? 105.455 552.414 73.804 1.00 33.99 ? 300 ARG A CD 1 ATOM 1670 N NE . ARG A 1 246 ? 104.874 552.297 75.143 1.00 36.12 ? 300 ARG A NE 1 ATOM 1671 C CZ . ARG A 1 246 ? 103.928 551.419 75.464 1.00 41.51 ? 300 ARG A CZ 1 ATOM 1672 N NH1 . ARG A 1 246 ? 103.452 550.580 74.550 1.00 22.56 ? 300 ARG A NH1 1 ATOM 1673 N NH2 . ARG A 1 246 ? 103.439 551.384 76.695 1.00 19.94 ? 300 ARG A NH2 1 ATOM 1674 N N . LEU A 1 247 ? 110.140 553.051 73.775 1.00 20.83 ? 301 LEU A N 1 ATOM 1675 C CA . LEU A 1 247 ? 111.099 552.080 74.302 1.00 19.88 ? 301 LEU A CA 1 ATOM 1676 C C . LEU A 1 247 ? 110.494 551.419 75.513 1.00 24.53 ? 301 LEU A C 1 ATOM 1677 O O . LEU A 1 247 ? 110.521 551.970 76.608 1.00 24.58 ? 301 LEU A O 1 ATOM 1678 C CB . LEU A 1 247 ? 112.460 552.746 74.650 1.00 19.63 ? 301 LEU A CB 1 ATOM 1679 C CG . LEU A 1 247 ? 113.177 553.379 73.469 1.00 24.00 ? 301 LEU A CG 1 ATOM 1680 C CD1 . LEU A 1 247 ? 114.382 554.171 73.906 1.00 24.62 ? 301 LEU A CD1 1 ATOM 1681 C CD2 . LEU A 1 247 ? 113.560 552.356 72.457 1.00 21.52 ? 301 LEU A CD2 1 ATOM 1682 N N . TYR A 1 248 ? 109.893 550.262 75.319 1.00 22.18 ? 302 TYR A N 1 ATOM 1683 C CA . TYR A 1 248 ? 109.292 549.502 76.412 1.00 20.05 ? 302 TYR A CA 1 ATOM 1684 C C . TYR A 1 248 ? 109.229 548.103 75.925 1.00 22.09 ? 302 TYR A C 1 ATOM 1685 O O . TYR A 1 248 ? 108.479 547.837 74.998 1.00 20.78 ? 302 TYR A O 1 ATOM 1686 C CB . TYR A 1 248 ? 107.883 550.006 76.755 1.00 19.78 ? 302 TYR A CB 1 ATOM 1687 C CG . TYR A 1 248 ? 107.426 549.600 78.146 1.00 20.24 ? 302 TYR A CG 1 ATOM 1688 C CD1 . TYR A 1 248 ? 108.183 549.915 79.267 1.00 21.39 ? 302 TYR A CD1 1 ATOM 1689 C CD2 . TYR A 1 248 ? 106.220 548.939 78.340 1.00 20.66 ? 302 TYR A CD2 1 ATOM 1690 C CE1 . TYR A 1 248 ? 107.744 549.614 80.541 1.00 23.06 ? 302 TYR A CE1 1 ATOM 1691 C CE2 . TYR A 1 248 ? 105.786 548.594 79.617 1.00 21.39 ? 302 TYR A CE2 1 ATOM 1692 C CZ . TYR A 1 248 ? 106.553 548.941 80.712 1.00 30.47 ? 302 TYR A CZ 1 ATOM 1693 O OH . TYR A 1 248 ? 106.159 548.648 81.983 1.00 34.03 ? 302 TYR A OH 1 ATOM 1694 N N . ASN A 1 249 ? 110.049 547.221 76.494 1.00 20.23 ? 303 ASN A N 1 ATOM 1695 C CA . ASN A 1 249 ? 110.154 545.836 76.028 1.00 20.46 ? 303 ASN A CA 1 ATOM 1696 C C . ASN A 1 249 ? 108.831 545.105 76.044 1.00 23.57 ? 303 ASN A C 1 ATOM 1697 O O . ASN A 1 249 ? 108.254 544.920 77.102 1.00 23.84 ? 303 ASN A O 1 ATOM 1698 C CB . ASN A 1 249 ? 111.231 545.095 76.809 1.00 22.08 ? 303 ASN A CB 1 ATOM 1699 C CG . ASN A 1 249 ? 112.601 545.664 76.604 1.00 30.85 ? 303 ASN A CG 1 ATOM 1700 O OD1 . ASN A 1 249 ? 112.819 546.543 75.761 1.00 17.84 ? 303 ASN A OD1 1 ATOM 1701 N ND2 . ASN A 1 249 ? 113.554 545.148 77.360 1.00 28.65 ? 303 ASN A ND2 1 ATOM 1702 N N . LEU A 1 250 ? 108.298 544.796 74.852 1.00 20.88 ? 304 LEU A N 1 ATOM 1703 C CA . LEU A 1 250 ? 106.963 544.223 74.690 1.00 19.83 ? 304 LEU A CA 1 ATOM 1704 C C . LEU A 1 250 ? 106.915 543.133 73.655 1.00 24.92 ? 304 LEU A C 1 ATOM 1705 O O . LEU A 1 250 ? 107.668 543.175 72.677 1.00 24.59 ? 304 LEU A O 1 ATOM 1706 C CB . LEU A 1 250 ? 105.955 545.305 74.302 1.00 19.01 ? 304 LEU A CB 1 ATOM 1707 C CG . LEU A 1 250 ? 105.646 546.359 75.337 1.00 24.06 ? 304 LEU A CG 1 ATOM 1708 C CD1 . LEU A 1 250 ? 104.864 547.482 74.744 1.00 24.12 ? 304 LEU A CD1 1 ATOM 1709 C CD2 . LEU A 1 250 ? 104.968 545.774 76.552 1.00 26.05 ? 304 LEU A CD2 1 ATOM 1710 N N . ASP A 1 251 ? 106.040 542.140 73.898 1.00 20.82 ? 305 ASP A N 1 ATOM 1711 C CA . ASP A 1 251 ? 105.768 541.030 73.011 1.00 20.57 ? 305 ASP A CA 1 ATOM 1712 C C . ASP A 1 251 ? 104.552 541.455 72.149 1.00 26.05 ? 305 ASP A C 1 ATOM 1713 O O . ASP A 1 251 ? 103.419 541.462 72.633 1.00 25.61 ? 305 ASP A O 1 ATOM 1714 C CB . ASP A 1 251 ? 105.455 539.787 73.854 1.00 22.00 ? 305 ASP A CB 1 ATOM 1715 C CG . ASP A 1 251 ? 105.081 538.532 73.078 1.00 25.54 ? 305 ASP A CG 1 ATOM 1716 O OD1 . ASP A 1 251 ? 104.904 538.612 71.839 1.00 27.05 ? 305 ASP A OD1 1 ATOM 1717 O OD2 . ASP A 1 251 ? 104.971 537.480 73.697 1.00 28.03 ? 305 ASP A OD2 1 ATOM 1718 N N . VAL A 1 252 ? 104.804 541.835 70.879 1.00 23.30 ? 306 VAL A N 1 ATOM 1719 C CA . VAL A 1 252 ? 103.817 542.370 69.936 1.00 21.73 ? 306 VAL A CA 1 ATOM 1720 C C . VAL A 1 252 ? 103.505 541.323 68.886 1.00 28.54 ? 306 VAL A C 1 ATOM 1721 O O . VAL A 1 252 ? 104.296 541.123 67.962 1.00 31.23 ? 306 VAL A O 1 ATOM 1722 C CB . VAL A 1 252 ? 104.372 543.695 69.335 1.00 24.05 ? 306 VAL A CB 1 ATOM 1723 C CG1 . VAL A 1 252 ? 103.378 544.365 68.401 1.00 23.08 ? 306 VAL A CG1 1 ATOM 1724 C CG2 . VAL A 1 252 ? 104.796 544.660 70.437 1.00 23.45 ? 306 VAL A CG2 1 ATOM 1725 N N . PHE A 1 253 ? 102.387 540.601 69.066 1.00 25.58 ? 307 PHE A N 1 ATOM 1726 C CA . PHE A 1 253 ? 101.964 539.515 68.176 1.00 26.19 ? 307 PHE A CA 1 ATOM 1727 C C . PHE A 1 253 ? 101.641 540.079 66.809 1.00 32.54 ? 307 PHE A C 1 ATOM 1728 O O . PHE A 1 253 ? 100.866 541.033 66.706 1.00 34.36 ? 307 PHE A O 1 ATOM 1729 C CB . PHE A 1 253 ? 100.743 538.794 68.785 1.00 28.17 ? 307 PHE A CB 1 ATOM 1730 C CG . PHE A 1 253 ? 100.200 537.605 68.031 1.00 29.23 ? 307 PHE A CG 1 ATOM 1731 C CD1 . PHE A 1 253 ? 100.839 536.375 68.091 1.00 32.38 ? 307 PHE A CD1 1 ATOM 1732 C CD2 . PHE A 1 253 ? 99.023 537.705 67.295 1.00 30.79 ? 307 PHE A CD2 1 ATOM 1733 C CE1 . PHE A 1 253 ? 100.343 535.279 67.376 1.00 33.42 ? 307 PHE A CE1 1 ATOM 1734 C CE2 . PHE A 1 253 ? 98.542 536.619 66.559 1.00 33.34 ? 307 PHE A CE2 1 ATOM 1735 C CZ . PHE A 1 253 ? 99.184 535.405 66.633 1.00 31.78 ? 307 PHE A CZ 1 ATOM 1736 N N . GLN A 1 254 ? 102.240 539.499 65.761 1.00 28.14 ? 308 GLN A N 1 ATOM 1737 C CA . GLN A 1 254 ? 102.027 539.920 64.380 1.00 27.70 ? 308 GLN A CA 1 ATOM 1738 C C . GLN A 1 254 ? 102.327 541.399 64.178 1.00 32.00 ? 308 GLN A C 1 ATOM 1739 O O . GLN A 1 254 ? 101.528 542.149 63.593 1.00 32.00 ? 308 GLN A O 1 ATOM 1740 C CB . GLN A 1 254 ? 100.633 539.532 63.877 1.00 28.65 ? 308 GLN A CB 1 ATOM 1741 C CG . GLN A 1 254 ? 100.505 538.033 63.655 1.00 36.35 ? 308 GLN A CG 1 ATOM 1742 C CD . GLN A 1 254 ? 99.172 537.604 63.102 1.00 52.20 ? 308 GLN A CD 1 ATOM 1743 O OE1 . GLN A 1 254 ? 98.137 538.231 63.318 1.00 50.54 ? 308 GLN A OE1 1 ATOM 1744 N NE2 . GLN A 1 254 ? 99.166 536.477 62.431 1.00 49.22 ? 308 GLN A NE2 1 ATOM 1745 N N . TYR A 1 255 ? 103.516 541.804 64.642 1.00 27.39 ? 309 TYR A N 1 ATOM 1746 C CA . TYR A 1 255 ? 103.958 543.177 64.516 1.00 26.00 ? 309 TYR A CA 1 ATOM 1747 C C . TYR A 1 255 ? 104.019 543.590 63.071 1.00 29.20 ? 309 TYR A C 1 ATOM 1748 O O . TYR A 1 255 ? 104.324 542.770 62.191 1.00 29.71 ? 309 TYR A O 1 ATOM 1749 C CB . TYR A 1 255 ? 105.262 543.457 65.284 1.00 25.27 ? 309 TYR A CB 1 ATOM 1750 C CG . TYR A 1 255 ? 106.555 542.901 64.720 1.00 26.89 ? 309 TYR A CG 1 ATOM 1751 C CD1 . TYR A 1 255 ? 107.179 543.499 63.623 1.00 28.51 ? 309 TYR A CD1 1 ATOM 1752 C CD2 . TYR A 1 255 ? 107.249 541.893 65.383 1.00 27.92 ? 309 TYR A CD2 1 ATOM 1753 C CE1 . TYR A 1 255 ? 108.414 543.047 63.156 1.00 26.13 ? 309 TYR A CE1 1 ATOM 1754 C CE2 . TYR A 1 255 ? 108.499 541.463 64.945 1.00 27.82 ? 309 TYR A CE2 1 ATOM 1755 C CZ . TYR A 1 255 ? 109.080 542.046 63.834 1.00 28.92 ? 309 TYR A CZ 1 ATOM 1756 O OH . TYR A 1 255 ? 110.312 541.605 63.404 1.00 26.09 ? 309 TYR A OH 1 ATOM 1757 N N . GLU A 1 256 ? 103.713 544.855 62.841 1.00 25.53 ? 310 GLU A N 1 ATOM 1758 C CA . GLU A 1 256 ? 103.643 545.438 61.505 1.00 26.09 ? 310 GLU A CA 1 ATOM 1759 C C . GLU A 1 256 ? 104.835 546.336 61.241 1.00 28.46 ? 310 GLU A C 1 ATOM 1760 O O . GLU A 1 256 ? 105.626 546.606 62.159 1.00 25.99 ? 310 GLU A O 1 ATOM 1761 C CB . GLU A 1 256 ? 102.298 546.155 61.301 1.00 27.66 ? 310 GLU A CB 1 ATOM 1762 C CG . GLU A 1 256 ? 101.156 545.176 61.096 1.00 36.46 ? 310 GLU A CG 1 ATOM 1763 C CD . GLU A 1 256 ? 99.771 545.795 61.101 1.00 49.91 ? 310 GLU A CD 1 ATOM 1764 O OE1 . GLU A 1 256 ? 99.651 547.013 60.823 1.00 28.90 ? 310 GLU A OE1 1 ATOM 1765 O OE2 . GLU A 1 256 ? 98.804 545.060 61.413 1.00 40.97 ? 310 GLU A OE2 1 ATOM 1766 N N . LEU A 1 257 ? 104.989 546.753 59.978 1.00 24.68 ? 311 LEU A N 1 ATOM 1767 C CA . LEU A 1 257 ? 106.158 547.487 59.547 1.00 23.91 ? 311 LEU A CA 1 ATOM 1768 C C . LEU A 1 257 ? 105.962 548.971 59.438 1.00 28.76 ? 311 LEU A C 1 ATOM 1769 O O . LEU A 1 257 ? 104.841 549.433 59.249 1.00 29.88 ? 311 LEU A O 1 ATOM 1770 C CB . LEU A 1 257 ? 106.677 546.930 58.218 1.00 22.86 ? 311 LEU A CB 1 ATOM 1771 C CG . LEU A 1 257 ? 106.886 545.427 58.069 1.00 25.93 ? 311 LEU A CG 1 ATOM 1772 C CD1 . LEU A 1 257 ? 107.585 545.140 56.799 1.00 25.42 ? 311 LEU A CD1 1 ATOM 1773 C CD2 . LEU A 1 257 ? 107.710 544.855 59.183 1.00 26.41 ? 311 LEU A CD2 1 ATOM 1774 N N . ASN A 1 258 ? 107.079 549.700 59.491 1.00 24.36 ? 312 ASN A N 1 ATOM 1775 C CA . ASN A 1 258 ? 107.224 551.144 59.352 1.00 26.05 ? 312 ASN A CA 1 ATOM 1776 C C . ASN A 1 258 ? 106.263 551.917 60.280 1.00 32.01 ? 312 ASN A C 1 ATOM 1777 O O . ASN A 1 258 ? 105.374 552.644 59.855 1.00 32.26 ? 312 ASN A O 1 ATOM 1778 C CB . ASN A 1 258 ? 107.176 551.566 57.889 1.00 31.69 ? 312 ASN A CB 1 ATOM 1779 C CG . ASN A 1 258 ? 108.348 550.940 57.110 1.00 63.89 ? 312 ASN A CG 1 ATOM 1780 O OD1 . ASN A 1 258 ? 109.544 551.195 57.382 1.00 57.05 ? 312 ASN A OD1 1 ATOM 1781 N ND2 . ASN A 1 258 ? 108.044 550.011 56.209 1.00 53.13 ? 312 ASN A ND2 1 ATOM 1782 N N . ASN A 1 259 ? 106.470 551.692 61.578 1.00 26.89 ? 313 ASN A N 1 ATOM 1783 C CA . ASN A 1 259 ? 105.754 552.331 62.634 1.00 26.17 ? 313 ASN A CA 1 ATOM 1784 C C . ASN A 1 259 ? 106.641 552.353 63.896 1.00 32.14 ? 313 ASN A C 1 ATOM 1785 O O . ASN A 1 259 ? 107.597 551.562 64.041 1.00 29.81 ? 313 ASN A O 1 ATOM 1786 C CB . ASN A 1 259 ? 104.398 551.691 62.854 1.00 24.96 ? 313 ASN A CB 1 ATOM 1787 C CG . ASN A 1 259 ? 104.416 550.397 63.606 1.00 31.17 ? 313 ASN A CG 1 ATOM 1788 O OD1 . ASN A 1 259 ? 104.849 550.321 64.730 1.00 29.64 ? 313 ASN A OD1 1 ATOM 1789 N ND2 . ASN A 1 259 ? 103.881 549.365 63.023 1.00 18.20 ? 313 ASN A ND2 1 ATOM 1790 N N . PRO A 1 260 ? 106.324 553.282 64.806 1.00 29.42 ? 314 PRO A N 1 ATOM 1791 C CA . PRO A 1 260 ? 107.157 553.462 65.998 1.00 29.10 ? 314 PRO A CA 1 ATOM 1792 C C . PRO A 1 260 ? 106.735 552.674 67.228 1.00 27.91 ? 314 PRO A C 1 ATOM 1793 O O . PRO A 1 260 ? 107.167 553.022 68.321 1.00 26.90 ? 314 PRO A O 1 ATOM 1794 C CB . PRO A 1 260 ? 107.006 554.956 66.252 1.00 31.25 ? 314 PRO A CB 1 ATOM 1795 C CG . PRO A 1 260 ? 105.546 555.187 65.931 1.00 34.59 ? 314 PRO A CG 1 ATOM 1796 C CD . PRO A 1 260 ? 105.249 554.298 64.756 1.00 30.07 ? 314 PRO A CD 1 ATOM 1797 N N . MET A 1 261 ? 105.860 551.669 67.079 1.00 22.51 ? 315 MET A N 1 ATOM 1798 C CA . MET A 1 261 ? 105.444 550.851 68.220 1.00 21.15 ? 315 MET A CA 1 ATOM 1799 C C . MET A 1 261 ? 106.680 550.160 68.870 1.00 25.97 ? 315 MET A C 1 ATOM 1800 O O . MET A 1 261 ? 107.605 549.718 68.166 1.00 23.84 ? 315 MET A O 1 ATOM 1801 C CB . MET A 1 261 ? 104.425 549.786 67.800 1.00 22.57 ? 315 MET A CB 1 ATOM 1802 C CG . MET A 1 261 ? 103.032 550.319 67.466 1.00 24.56 ? 315 MET A CG 1 ATOM 1803 S SD . MET A 1 261 ? 101.941 548.963 66.934 1.00 25.86 ? 315 MET A SD 1 ATOM 1804 C CE . MET A 1 261 ? 101.542 548.223 68.497 1.00 23.41 ? 315 MET A CE 1 ATOM 1805 N N . ALA A 1 262 ? 106.686 550.088 70.212 1.00 21.93 ? 316 ALA A N 1 ATOM 1806 C CA . ALA A 1 262 ? 107.754 549.429 70.940 1.00 20.89 ? 316 ALA A CA 1 ATOM 1807 C C . ALA A 1 262 ? 107.749 547.933 70.689 1.00 26.12 ? 316 ALA A C 1 ATOM 1808 O O . ALA A 1 262 ? 106.708 547.278 70.829 1.00 23.04 ? 316 ALA A O 1 ATOM 1809 C CB . ALA A 1 262 ? 107.574 549.674 72.413 1.00 21.51 ? 316 ALA A CB 1 ATOM 1810 N N . LEU A 1 263 ? 108.920 547.380 70.324 1.00 25.19 ? 317 LEU A N 1 ATOM 1811 C CA . LEU A 1 263 ? 109.063 545.937 70.211 1.00 23.56 ? 317 LEU A CA 1 ATOM 1812 C C . LEU A 1 263 ? 109.795 545.361 71.468 1.00 27.35 ? 317 LEU A C 1 ATOM 1813 O O . LEU A 1 263 ? 109.734 545.958 72.560 1.00 27.70 ? 317 LEU A O 1 ATOM 1814 C CB . LEU A 1 263 ? 109.652 545.509 68.861 1.00 22.60 ? 317 LEU A CB 1 ATOM 1815 C CG . LEU A 1 263 ? 108.803 545.935 67.634 1.00 24.25 ? 317 LEU A CG 1 ATOM 1816 C CD1 . LEU A 1 263 ? 109.490 545.579 66.310 1.00 23.68 ? 317 LEU A CD1 1 ATOM 1817 C CD2 . LEU A 1 263 ? 107.443 545.291 67.665 1.00 21.08 ? 317 LEU A CD2 1 ATOM 1818 N N . TYR A 1 264 ? 110.449 544.219 71.318 1.00 21.48 ? 318 TYR A N 1 ATOM 1819 C CA . TYR A 1 264 ? 110.946 543.380 72.404 1.00 20.26 ? 318 TYR A CA 1 ATOM 1820 C C . TYR A 1 264 ? 112.098 543.911 73.197 1.00 23.38 ? 318 TYR A C 1 ATOM 1821 O O . TYR A 1 264 ? 112.293 543.482 74.349 1.00 21.43 ? 318 TYR A O 1 ATOM 1822 C CB . TYR A 1 264 ? 111.323 541.977 71.873 1.00 20.21 ? 318 TYR A CB 1 ATOM 1823 C CG . TYR A 1 264 ? 110.335 541.388 70.894 1.00 21.06 ? 318 TYR A CG 1 ATOM 1824 C CD1 . TYR A 1 264 ? 109.244 540.639 71.334 1.00 23.72 ? 318 TYR A CD1 1 ATOM 1825 C CD2 . TYR A 1 264 ? 110.501 541.554 69.525 1.00 20.97 ? 318 TYR A CD2 1 ATOM 1826 C CE1 . TYR A 1 264 ? 108.329 540.087 70.431 1.00 25.31 ? 318 TYR A CE1 1 ATOM 1827 C CE2 . TYR A 1 264 ? 109.597 541.006 68.616 1.00 22.43 ? 318 TYR A CE2 1 ATOM 1828 C CZ . TYR A 1 264 ? 108.514 540.271 69.071 1.00 29.66 ? 318 TYR A CZ 1 ATOM 1829 O OH . TYR A 1 264 ? 107.662 539.709 68.148 1.00 30.05 ? 318 TYR A OH 1 ATOM 1830 N N . GLY A 1 265 ? 112.895 544.759 72.546 1.00 19.41 ? 319 GLY A N 1 ATOM 1831 C CA . GLY A 1 265 ? 114.102 545.327 73.122 1.00 18.45 ? 319 GLY A CA 1 ATOM 1832 C C . GLY A 1 265 ? 114.147 546.821 73.041 1.00 21.98 ? 319 GLY A C 1 ATOM 1833 O O . GLY A 1 265 ? 113.405 547.429 72.267 1.00 20.40 ? 319 GLY A O 1 ATOM 1834 N N . SER A 1 266 ? 115.001 547.420 73.872 1.00 21.83 ? 320 SER A N 1 ATOM 1835 C CA . SER A 1 266 ? 115.099 548.875 74.008 1.00 21.79 ? 320 SER A CA 1 ATOM 1836 C C . SER A 1 266 ? 116.526 549.260 74.277 1.00 25.72 ? 320 SER A C 1 ATOM 1837 O O . SER A 1 266 ? 117.048 548.900 75.337 1.00 25.29 ? 320 SER A O 1 ATOM 1838 C CB . SER A 1 266 ? 114.261 549.364 75.197 1.00 23.23 ? 320 SER A CB 1 ATOM 1839 O OG . SER A 1 266 ? 112.870 549.260 74.987 1.00 30.95 ? 320 SER A OG 1 ATOM 1840 N N . VAL A 1 267 ? 117.153 550.017 73.363 1.00 22.31 ? 321 VAL A N 1 ATOM 1841 C CA . VAL A 1 267 ? 118.518 550.511 73.572 1.00 21.27 ? 321 VAL A CA 1 ATOM 1842 C C . VAL A 1 267 ? 118.427 552.022 73.482 1.00 25.37 ? 321 VAL A C 1 ATOM 1843 O O . VAL A 1 267 ? 118.278 552.557 72.395 1.00 25.59 ? 321 VAL A O 1 ATOM 1844 C CB . VAL A 1 267 ? 119.566 549.923 72.616 1.00 24.20 ? 321 VAL A CB 1 ATOM 1845 C CG1 . VAL A 1 267 ? 120.957 550.445 72.964 1.00 23.65 ? 321 VAL A CG1 1 ATOM 1846 C CG2 . VAL A 1 267 ? 119.543 548.391 72.638 1.00 23.29 ? 321 VAL A CG2 1 ATOM 1847 N N . PRO A 1 268 ? 118.477 552.733 74.610 1.00 22.83 ? 322 PRO A N 1 ATOM 1848 C CA . PRO A 1 268 ? 118.251 554.182 74.569 1.00 22.93 ? 322 PRO A CA 1 ATOM 1849 C C . PRO A 1 268 ? 119.493 554.969 74.162 1.00 28.59 ? 322 PRO A C 1 ATOM 1850 O O . PRO A 1 268 ? 120.077 555.733 74.941 1.00 29.91 ? 322 PRO A O 1 ATOM 1851 C CB . PRO A 1 268 ? 117.762 554.472 75.981 1.00 23.82 ? 322 PRO A CB 1 ATOM 1852 C CG . PRO A 1 268 ? 118.549 553.528 76.813 1.00 28.72 ? 322 PRO A CG 1 ATOM 1853 C CD . PRO A 1 268 ? 118.629 552.255 75.999 1.00 24.44 ? 322 PRO A CD 1 ATOM 1854 N N . VAL A 1 269 ? 119.894 554.760 72.908 1.00 23.79 ? 323 VAL A N 1 ATOM 1855 C CA . VAL A 1 269 ? 121.078 555.358 72.330 1.00 22.90 ? 323 VAL A CA 1 ATOM 1856 C C . VAL A 1 269 ? 120.691 555.861 70.981 1.00 28.52 ? 323 VAL A C 1 ATOM 1857 O O . VAL A 1 269 ? 120.181 555.104 70.153 1.00 30.31 ? 323 VAL A O 1 ATOM 1858 C CB . VAL A 1 269 ? 122.250 554.357 72.237 1.00 25.12 ? 323 VAL A CB 1 ATOM 1859 C CG1 . VAL A 1 269 ? 123.471 554.987 71.564 1.00 24.57 ? 323 VAL A CG1 1 ATOM 1860 C CG2 . VAL A 1 269 ? 122.603 553.783 73.598 1.00 24.13 ? 323 VAL A CG2 1 ATOM 1861 N N . LEU A 1 270 ? 120.932 557.146 70.760 1.00 24.93 ? 324 LEU A N 1 ATOM 1862 C CA . LEU A 1 270 ? 120.650 557.790 69.493 1.00 24.10 ? 324 LEU A CA 1 ATOM 1863 C C . LEU A 1 270 ? 121.949 558.301 68.884 1.00 27.43 ? 324 LEU A C 1 ATOM 1864 O O . LEU A 1 270 ? 122.703 558.973 69.562 1.00 28.51 ? 324 LEU A O 1 ATOM 1865 C CB . LEU A 1 270 ? 119.669 558.940 69.711 1.00 23.58 ? 324 LEU A CB 1 ATOM 1866 C CG . LEU A 1 270 ? 119.247 559.629 68.430 1.00 27.74 ? 324 LEU A CG 1 ATOM 1867 C CD1 . LEU A 1 270 ? 117.767 559.716 68.334 1.00 27.63 ? 324 LEU A CD1 1 ATOM 1868 C CD2 . LEU A 1 270 ? 119.953 560.958 68.239 1.00 24.93 ? 324 LEU A CD2 1 ATOM 1869 N N . LEU A 1 271 ? 122.195 558.001 67.618 1.00 23.25 ? 325 LEU A N 1 ATOM 1870 C CA . LEU A 1 271 ? 123.352 558.499 66.894 1.00 23.15 ? 325 LEU A CA 1 ATOM 1871 C C . LEU A 1 271 ? 122.902 559.547 65.905 1.00 26.09 ? 325 LEU A C 1 ATOM 1872 O O . LEU A 1 271 ? 121.827 559.445 65.319 1.00 24.45 ? 325 LEU A O 1 ATOM 1873 C CB . LEU A 1 271 ? 124.094 557.360 66.166 1.00 23.58 ? 325 LEU A CB 1 ATOM 1874 C CG . LEU A 1 271 ? 125.259 556.704 66.901 1.00 27.94 ? 325 LEU A CG 1 ATOM 1875 C CD1 . LEU A 1 271 ? 124.869 556.195 68.276 1.00 27.48 ? 325 LEU A CD1 1 ATOM 1876 C CD2 . LEU A 1 271 ? 125.855 555.599 66.052 1.00 30.13 ? 325 LEU A CD2 1 ATOM 1877 N N . ALA A 1 272 ? 123.714 560.584 65.762 1.00 24.06 ? 326 ALA A N 1 ATOM 1878 C CA . ALA A 1 272 ? 123.464 561.656 64.825 1.00 23.06 ? 326 ALA A CA 1 ATOM 1879 C C . ALA A 1 272 ? 124.683 561.796 63.884 1.00 27.32 ? 326 ALA A C 1 ATOM 1880 O O . ALA A 1 272 ? 125.828 561.868 64.338 1.00 26.43 ? 326 ALA A O 1 ATOM 1881 C CB . ALA A 1 272 ? 123.143 562.946 65.565 1.00 23.20 ? 326 ALA A CB 1 ATOM 1882 N N . HIS A 1 273 ? 124.421 561.778 62.570 1.00 24.87 ? 327 HIS A N 1 ATOM 1883 C CA . HIS A 1 273 ? 125.469 561.873 61.566 1.00 26.34 ? 327 HIS A CA 1 ATOM 1884 C C . HIS A 1 273 ? 125.257 563.030 60.595 1.00 34.99 ? 327 HIS A C 1 ATOM 1885 O O . HIS A 1 273 ? 124.147 563.236 60.101 1.00 35.87 ? 327 HIS A O 1 ATOM 1886 C CB . HIS A 1 273 ? 125.532 560.579 60.732 1.00 26.44 ? 327 HIS A CB 1 ATOM 1887 C CG . HIS A 1 273 ? 126.602 560.623 59.696 1.00 28.84 ? 327 HIS A CG 1 ATOM 1888 N ND1 . HIS A 1 273 ? 127.932 560.510 60.052 1.00 30.46 ? 327 HIS A ND1 1 ATOM 1889 C CD2 . HIS A 1 273 ? 126.525 560.874 58.372 1.00 30.70 ? 327 HIS A CD2 1 ATOM 1890 C CE1 . HIS A 1 273 ? 128.624 560.651 58.943 1.00 30.03 ? 327 HIS A CE1 1 ATOM 1891 N NE2 . HIS A 1 273 ? 127.823 560.883 57.902 1.00 30.61 ? 327 HIS A NE2 1 ATOM 1892 N N . SER A 1 274 ? 126.338 563.737 60.271 1.00 32.49 ? 328 SER A N 1 ATOM 1893 C CA . SER A 1 274 ? 126.347 564.728 59.205 1.00 32.61 ? 328 SER A CA 1 ATOM 1894 C C . SER A 1 274 ? 127.681 564.528 58.495 1.00 40.00 ? 328 SER A C 1 ATOM 1895 O O . SER A 1 274 ? 128.560 563.817 59.011 1.00 39.56 ? 328 SER A O 1 ATOM 1896 C CB . SER A 1 274 ? 126.232 566.148 59.761 1.00 33.60 ? 328 SER A CB 1 ATOM 1897 O OG . SER A 1 274 ? 127.440 566.598 60.356 1.00 35.31 ? 328 SER A OG 1 ATOM 1898 N N . PHE A 1 275 ? 127.856 565.196 57.340 1.00 38.82 ? 329 PHE A N 1 ATOM 1899 C CA . PHE A 1 275 ? 129.120 565.276 56.598 1.00 38.27 ? 329 PHE A CA 1 ATOM 1900 C C . PHE A 1 275 ? 130.271 565.706 57.533 1.00 41.25 ? 329 PHE A C 1 ATOM 1901 O O . PHE A 1 275 ? 131.398 565.270 57.327 1.00 40.88 ? 329 PHE A O 1 ATOM 1902 C CB . PHE A 1 275 ? 128.986 566.314 55.446 1.00 40.40 ? 329 PHE A CB 1 ATOM 1903 C CG . PHE A 1 275 ? 130.254 566.651 54.674 1.00 42.87 ? 329 PHE A CG 1 ATOM 1904 C CD1 . PHE A 1 275 ? 131.207 567.521 55.204 1.00 45.88 ? 329 PHE A CD1 1 ATOM 1905 C CD2 . PHE A 1 275 ? 130.474 566.134 53.403 1.00 45.38 ? 329 PHE A CD2 1 ATOM 1906 C CE1 . PHE A 1 275 ? 132.385 567.796 54.517 1.00 46.52 ? 329 PHE A CE1 1 ATOM 1907 C CE2 . PHE A 1 275 ? 131.638 566.448 52.694 1.00 48.30 ? 329 PHE A CE2 1 ATOM 1908 C CZ . PHE A 1 275 ? 132.587 567.270 53.260 1.00 46.51 ? 329 PHE A CZ 1 ATOM 1909 N N . HIS A 1 276 ? 129.990 566.569 58.537 1.00 38.23 ? 330 HIS A N 1 ATOM 1910 C CA . HIS A 1 276 ? 131.003 567.197 59.398 1.00 39.04 ? 330 HIS A CA 1 ATOM 1911 C C . HIS A 1 276 ? 131.350 566.475 60.672 1.00 36.58 ? 330 HIS A C 1 ATOM 1912 O O . HIS A 1 276 ? 132.491 566.581 61.136 1.00 35.02 ? 330 HIS A O 1 ATOM 1913 C CB . HIS A 1 276 ? 130.586 568.650 59.748 1.00 41.79 ? 330 HIS A CB 1 ATOM 1914 C CG . HIS A 1 276 ? 130.418 569.533 58.541 1.00 47.27 ? 330 HIS A CG 1 ATOM 1915 N ND1 . HIS A 1 276 ? 131.522 570.045 57.855 1.00 50.04 ? 330 HIS A ND1 1 ATOM 1916 C CD2 . HIS A 1 276 ? 129.284 569.935 57.906 1.00 50.16 ? 330 HIS A CD2 1 ATOM 1917 C CE1 . HIS A 1 276 ? 131.022 570.752 56.848 1.00 49.95 ? 330 HIS A CE1 1 ATOM 1918 N NE2 . HIS A 1 276 ? 129.680 570.704 56.827 1.00 50.28 ? 330 HIS A NE2 1 ATOM 1919 N N . ARG A 1 277 ? 130.367 565.804 61.282 1.00 29.72 ? 331 ARG A N 1 ATOM 1920 C CA . ARG A 1 277 ? 130.590 565.189 62.576 1.00 28.65 ? 331 ARG A CA 1 ATOM 1921 C C . ARG A 1 277 ? 129.618 564.062 62.897 1.00 32.04 ? 331 ARG A C 1 ATOM 1922 O O . ARG A 1 277 ? 128.582 563.876 62.242 1.00 29.96 ? 331 ARG A O 1 ATOM 1923 C CB . ARG A 1 277 ? 130.445 566.274 63.663 1.00 26.24 ? 331 ARG A CB 1 ATOM 1924 C CG . ARG A 1 277 ? 131.336 566.059 64.863 1.00 29.75 ? 331 ARG A CG 1 ATOM 1925 C CD . ARG A 1 277 ? 131.126 567.105 65.937 1.00 39.15 ? 331 ARG A CD 1 ATOM 1926 N NE . ARG A 1 277 ? 131.915 566.740 67.106 1.00 38.47 ? 331 ARG A NE 1 ATOM 1927 C CZ . ARG A 1 277 ? 133.072 567.290 67.438 1.00 48.82 ? 331 ARG A CZ 1 ATOM 1928 N NH1 . ARG A 1 277 ? 133.561 568.298 66.730 1.00 41.06 ? 331 ARG A NH1 1 ATOM 1929 N NH2 . ARG A 1 277 ? 133.740 566.853 68.495 1.00 33.77 ? 331 ARG A NH2 1 ATOM 1930 N N . ASP A 1 278 ? 129.951 563.346 63.980 1.00 27.92 ? 332 ASP A N 1 ATOM 1931 C CA . ASP A 1 278 ? 129.115 562.316 64.568 1.00 26.51 ? 332 ASP A CA 1 ATOM 1932 C C . ASP A 1 278 ? 128.991 562.566 66.038 1.00 29.35 ? 332 ASP A C 1 ATOM 1933 O O . ASP A 1 278 ? 129.986 562.912 66.704 1.00 28.91 ? 332 ASP A O 1 ATOM 1934 C CB . ASP A 1 278 ? 129.687 560.928 64.322 1.00 26.75 ? 332 ASP A CB 1 ATOM 1935 C CG . ASP A 1 278 ? 129.514 560.508 62.902 1.00 30.85 ? 332 ASP A CG 1 ATOM 1936 O OD1 . ASP A 1 278 ? 128.442 559.963 62.581 1.00 35.18 ? 332 ASP A OD1 1 ATOM 1937 O OD2 . ASP A 1 278 ? 130.431 560.749 62.100 1.00 33.16 ? 332 ASP A OD2 1 ATOM 1938 N N . LEU A 1 279 ? 127.754 562.413 66.537 1.00 23.72 ? 333 LEU A N 1 ATOM 1939 C CA . LEU A 1 279 ? 127.420 562.546 67.951 1.00 21.69 ? 333 LEU A CA 1 ATOM 1940 C C . LEU A 1 279 ? 126.541 561.389 68.367 1.00 21.84 ? 333 LEU A C 1 ATOM 1941 O O . LEU A 1 279 ? 125.871 560.744 67.547 1.00 17.96 ? 333 LEU A O 1 ATOM 1942 C CB . LEU A 1 279 ? 126.680 563.874 68.240 1.00 21.18 ? 333 LEU A CB 1 ATOM 1943 C CG . LEU A 1 279 ? 127.354 565.170 67.782 1.00 25.90 ? 333 LEU A CG 1 ATOM 1944 C CD1 . LEU A 1 279 ? 126.462 566.336 68.053 1.00 25.50 ? 333 LEU A CD1 1 ATOM 1945 C CD2 . LEU A 1 279 ? 128.677 565.393 68.486 1.00 27.30 ? 333 LEU A CD2 1 ATOM 1946 N N . GLY A 1 280 ? 126.534 561.145 69.657 1.00 20.16 ? 334 GLY A N 1 ATOM 1947 C CA . GLY A 1 280 ? 125.650 560.141 70.219 1.00 20.55 ? 334 GLY A CA 1 ATOM 1948 C C . GLY A 1 280 ? 125.111 560.619 71.535 1.00 21.99 ? 334 GLY A C 1 ATOM 1949 O O . GLY A 1 280 ? 125.768 561.395 72.230 1.00 20.68 ? 334 GLY A O 1 ATOM 1950 N N . ILE A 1 281 ? 123.908 560.204 71.842 1.00 20.20 ? 335 ILE A N 1 ATOM 1951 C CA . ILE A 1 281 ? 123.218 560.530 73.091 1.00 20.75 ? 335 ILE A CA 1 ATOM 1952 C C . ILE A 1 281 ? 122.825 559.198 73.674 1.00 22.83 ? 335 ILE A C 1 ATOM 1953 O O . ILE A 1 281 ? 122.176 558.405 72.995 1.00 22.79 ? 335 ILE A O 1 ATOM 1954 C CB . ILE A 1 281 ? 121.958 561.434 72.878 1.00 24.41 ? 335 ILE A CB 1 ATOM 1955 C CG1 . ILE A 1 281 ? 122.306 562.782 72.219 1.00 24.88 ? 335 ILE A CG1 1 ATOM 1956 C CG2 . ILE A 1 281 ? 121.225 561.670 74.205 1.00 25.50 ? 335 ILE A CG2 1 ATOM 1957 C CD1 . ILE A 1 281 ? 121.097 563.516 71.704 1.00 24.84 ? 335 ILE A CD1 1 ATOM 1958 N N . PHE A 1 282 ? 123.244 558.940 74.900 1.00 19.29 ? 336 PHE A N 1 ATOM 1959 C CA . PHE A 1 282 ? 122.916 557.726 75.619 1.00 19.03 ? 336 PHE A CA 1 ATOM 1960 C C . PHE A 1 282 ? 122.144 558.100 76.890 1.00 21.81 ? 336 PHE A C 1 ATOM 1961 O O . PHE A 1 282 ? 122.689 558.689 77.821 1.00 19.28 ? 336 PHE A O 1 ATOM 1962 C CB . PHE A 1 282 ? 124.197 556.916 75.869 1.00 21.35 ? 336 PHE A CB 1 ATOM 1963 C CG . PHE A 1 282 ? 124.084 555.764 76.841 1.00 22.33 ? 336 PHE A CG 1 ATOM 1964 C CD1 . PHE A 1 282 ? 122.930 554.988 76.899 1.00 24.45 ? 336 PHE A CD1 1 ATOM 1965 C CD2 . PHE A 1 282 ? 125.150 555.425 77.664 1.00 23.39 ? 336 PHE A CD2 1 ATOM 1966 C CE1 . PHE A 1 282 ? 122.839 553.907 77.779 1.00 25.43 ? 336 PHE A CE1 1 ATOM 1967 C CE2 . PHE A 1 282 ? 125.058 554.349 78.550 1.00 25.82 ? 336 PHE A CE2 1 ATOM 1968 C CZ . PHE A 1 282 ? 123.904 553.597 78.605 1.00 24.06 ? 336 PHE A CZ 1 ATOM 1969 N N . TRP A 1 283 ? 120.843 557.812 76.875 1.00 20.65 ? 337 TRP A N 1 ATOM 1970 C CA . TRP A 1 283 ? 119.898 558.145 77.937 1.00 20.82 ? 337 TRP A CA 1 ATOM 1971 C C . TRP A 1 283 ? 119.773 556.929 78.851 1.00 23.10 ? 337 TRP A C 1 ATOM 1972 O O . TRP A 1 283 ? 119.053 555.990 78.562 1.00 20.33 ? 337 TRP A O 1 ATOM 1973 C CB . TRP A 1 283 ? 118.580 558.585 77.282 1.00 20.26 ? 337 TRP A CB 1 ATOM 1974 C CG . TRP A 1 283 ? 117.482 558.998 78.210 1.00 22.02 ? 337 TRP A CG 1 ATOM 1975 C CD1 . TRP A 1 283 ? 116.466 558.214 78.665 1.00 24.74 ? 337 TRP A CD1 1 ATOM 1976 C CD2 . TRP A 1 283 ? 117.211 560.325 78.693 1.00 22.56 ? 337 TRP A CD2 1 ATOM 1977 N NE1 . TRP A 1 283 ? 115.611 558.952 79.450 1.00 23.83 ? 337 TRP A NE1 1 ATOM 1978 C CE2 . TRP A 1 283 ? 116.053 560.248 79.500 1.00 26.04 ? 337 TRP A CE2 1 ATOM 1979 C CE3 . TRP A 1 283 ? 117.840 561.574 78.537 1.00 23.44 ? 337 TRP A CE3 1 ATOM 1980 C CZ2 . TRP A 1 283 ? 115.513 561.373 80.152 1.00 25.23 ? 337 TRP A CZ2 1 ATOM 1981 C CZ3 . TRP A 1 283 ? 117.281 562.686 79.156 1.00 24.63 ? 337 TRP A CZ3 1 ATOM 1982 C CH2 . TRP A 1 283 ? 116.142 562.575 79.964 1.00 25.10 ? 337 TRP A CH2 1 ATOM 1983 N N . LEU A 1 284 ? 120.537 556.929 79.947 1.00 21.60 ? 338 LEU A N 1 ATOM 1984 C CA . LEU A 1 284 ? 120.584 555.801 80.846 1.00 20.04 ? 338 LEU A CA 1 ATOM 1985 C C . LEU A 1 284 ? 119.397 555.797 81.784 1.00 23.64 ? 338 LEU A C 1 ATOM 1986 O O . LEU A 1 284 ? 119.453 556.344 82.870 1.00 23.27 ? 338 LEU A O 1 ATOM 1987 C CB . LEU A 1 284 ? 121.935 555.723 81.564 1.00 19.74 ? 338 LEU A CB 1 ATOM 1988 C CG . LEU A 1 284 ? 122.166 554.503 82.486 1.00 24.28 ? 338 LEU A CG 1 ATOM 1989 C CD1 . LEU A 1 284 ? 121.902 553.223 81.777 1.00 24.18 ? 338 LEU A CD1 1 ATOM 1990 C CD2 . LEU A 1 284 ? 123.563 554.477 82.972 1.00 27.46 ? 338 LEU A CD2 1 ATOM 1991 N N . ASN A 1 285 ? 118.315 555.151 81.342 1.00 21.27 ? 339 ASN A N 1 ATOM 1992 C CA . ASN A 1 285 ? 117.045 555.033 82.062 1.00 20.11 ? 339 ASN A CA 1 ATOM 1993 C C . ASN A 1 285 ? 116.397 553.718 81.668 1.00 23.12 ? 339 ASN A C 1 ATOM 1994 O O . ASN A 1 285 ? 116.302 553.409 80.469 1.00 21.95 ? 339 ASN A O 1 ATOM 1995 C CB . ASN A 1 285 ? 116.127 556.229 81.747 1.00 15.88 ? 339 ASN A CB 1 ATOM 1996 C CG . ASN A 1 285 ? 114.971 556.383 82.694 1.00 27.34 ? 339 ASN A CG 1 ATOM 1997 O OD1 . ASN A 1 285 ? 114.054 555.583 82.675 1.00 23.32 ? 339 ASN A OD1 1 ATOM 1998 N ND2 . ASN A 1 285 ? 114.966 557.433 83.512 1.00 22.11 ? 339 ASN A ND2 1 ATOM 1999 N N . ALA A 1 286 ? 115.943 552.947 82.675 1.00 19.17 ? 340 ALA A N 1 ATOM 2000 C CA . ALA A 1 286 ? 115.349 551.623 82.463 1.00 18.17 ? 340 ALA A CA 1 ATOM 2001 C C . ALA A 1 286 ? 113.848 551.649 82.423 1.00 22.46 ? 340 ALA A C 1 ATOM 2002 O O . ALA A 1 286 ? 113.225 550.602 82.208 1.00 20.92 ? 340 ALA A O 1 ATOM 2003 C CB . ALA A 1 286 ? 115.818 550.653 83.538 1.00 18.09 ? 340 ALA A CB 1 ATOM 2004 N N . ALA A 1 287 ? 113.248 552.819 82.640 1.00 20.18 ? 341 ALA A N 1 ATOM 2005 C CA . ALA A 1 287 ? 111.794 552.891 82.680 1.00 20.28 ? 341 ALA A CA 1 ATOM 2006 C C . ALA A 1 287 ? 111.218 553.116 81.271 1.00 24.42 ? 341 ALA A C 1 ATOM 2007 O O . ALA A 1 287 ? 111.967 553.447 80.358 1.00 22.08 ? 341 ALA A O 1 ATOM 2008 C CB . ALA A 1 287 ? 111.364 553.996 83.636 1.00 20.56 ? 341 ALA A CB 1 ATOM 2009 N N . GLU A 1 288 ? 109.887 552.926 81.093 1.00 22.46 ? 342 GLU A N 1 ATOM 2010 C CA . GLU A 1 288 ? 109.190 553.227 79.836 1.00 21.57 ? 342 GLU A CA 1 ATOM 2011 C C . GLU A 1 288 ? 109.625 554.591 79.355 1.00 26.69 ? 342 GLU A C 1 ATOM 2012 O O . GLU A 1 288 ? 109.601 555.564 80.103 1.00 26.87 ? 342 GLU A O 1 ATOM 2013 C CB . GLU A 1 288 ? 107.674 553.194 80.014 1.00 22.92 ? 342 GLU A CB 1 ATOM 2014 C CG . GLU A 1 288 ? 106.932 553.360 78.704 1.00 26.33 ? 342 GLU A CG 1 ATOM 2015 C CD . GLU A 1 288 ? 105.428 553.245 78.815 1.00 40.18 ? 342 GLU A CD 1 ATOM 2016 O OE1 . GLU A 1 288 ? 104.925 552.738 79.841 1.00 38.13 ? 342 GLU A OE1 1 ATOM 2017 O OE2 . GLU A 1 288 ? 104.747 553.629 77.843 1.00 29.10 ? 342 GLU A OE2 1 ATOM 2018 N N . THR A 1 289 ? 110.079 554.640 78.117 1.00 23.81 ? 343 THR A N 1 ATOM 2019 C CA . THR A 1 289 ? 110.656 555.846 77.552 1.00 23.06 ? 343 THR A CA 1 ATOM 2020 C C . THR A 1 289 ? 110.093 556.142 76.176 1.00 24.23 ? 343 THR A C 1 ATOM 2021 O O . THR A 1 289 ? 110.045 555.273 75.329 1.00 22.66 ? 343 THR A O 1 ATOM 2022 C CB . THR A 1 289 ? 112.230 555.733 77.580 1.00 28.27 ? 343 THR A CB 1 ATOM 2023 O OG1 . THR A 1 289 ? 112.709 555.711 78.929 1.00 22.75 ? 343 THR A OG1 1 ATOM 2024 C CG2 . THR A 1 289 ? 112.910 556.866 76.872 1.00 23.82 ? 343 THR A CG2 1 ATOM 2025 N N . TRP A 1 290 ? 109.731 557.396 75.947 1.00 22.76 ? 344 TRP A N 1 ATOM 2026 C CA . TRP A 1 290 ? 109.255 557.871 74.655 1.00 22.46 ? 344 TRP A CA 1 ATOM 2027 C C . TRP A 1 290 ? 110.234 558.892 74.140 1.00 26.91 ? 344 TRP A C 1 ATOM 2028 O O . TRP A 1 290 ? 110.710 559.725 74.912 1.00 25.96 ? 344 TRP A O 1 ATOM 2029 C CB . TRP A 1 290 ? 107.872 558.508 74.748 1.00 21.39 ? 344 TRP A CB 1 ATOM 2030 C CG . TRP A 1 290 ? 106.816 557.606 75.282 1.00 22.15 ? 344 TRP A CG 1 ATOM 2031 C CD1 . TRP A 1 290 ? 106.587 557.314 76.595 1.00 25.05 ? 344 TRP A CD1 1 ATOM 2032 C CD2 . TRP A 1 290 ? 105.796 556.924 74.530 1.00 21.68 ? 344 TRP A CD2 1 ATOM 2033 N NE1 . TRP A 1 290 ? 105.509 556.458 76.708 1.00 24.53 ? 344 TRP A NE1 1 ATOM 2034 C CE2 . TRP A 1 290 ? 104.998 556.210 75.460 1.00 25.49 ? 344 TRP A CE2 1 ATOM 2035 C CE3 . TRP A 1 290 ? 105.503 556.811 73.162 1.00 23.00 ? 344 TRP A CE3 1 ATOM 2036 C CZ2 . TRP A 1 290 ? 103.886 555.450 75.075 1.00 24.68 ? 344 TRP A CZ2 1 ATOM 2037 C CZ3 . TRP A 1 290 ? 104.410 556.030 72.776 1.00 25.03 ? 344 TRP A CZ3 1 ATOM 2038 C CH2 . TRP A 1 290 ? 103.605 555.378 73.730 1.00 25.63 ? 344 TRP A CH2 1 ATOM 2039 N N . VAL A 1 291 ? 110.526 558.845 72.814 1.00 23.20 ? 345 VAL A N 1 ATOM 2040 C CA . VAL A 1 291 ? 111.464 559.732 72.161 1.00 20.83 ? 345 VAL A CA 1 ATOM 2041 C C . VAL A 1 291 ? 110.814 560.501 71.033 1.00 27.48 ? 345 VAL A C 1 ATOM 2042 O O . VAL A 1 291 ? 110.346 559.898 70.049 1.00 29.08 ? 345 VAL A O 1 ATOM 2043 C CB . VAL A 1 291 ? 112.707 558.974 71.670 1.00 23.50 ? 345 VAL A CB 1 ATOM 2044 C CG1 . VAL A 1 291 ? 113.767 559.947 71.199 1.00 23.33 ? 345 VAL A CG1 1 ATOM 2045 C CG2 . VAL A 1 291 ? 113.277 558.076 72.746 1.00 23.25 ? 345 VAL A CG2 1 ATOM 2046 N N . ASP A 1 292 ? 110.784 561.831 71.167 1.00 23.44 ? 346 ASP A N 1 ATOM 2047 C CA . ASP A 1 292 ? 110.277 562.687 70.110 1.00 23.53 ? 346 ASP A CA 1 ATOM 2048 C C . ASP A 1 292 ? 111.430 563.250 69.306 1.00 27.98 ? 346 ASP A C 1 ATOM 2049 O O . ASP A 1 292 ? 112.464 563.625 69.847 1.00 25.91 ? 346 ASP A O 1 ATOM 2050 C CB . ASP A 1 292 ? 109.366 563.796 70.639 1.00 25.85 ? 346 ASP A CB 1 ATOM 2051 C CG . ASP A 1 292 ? 107.858 563.506 70.592 1.00 31.45 ? 346 ASP A CG 1 ATOM 2052 O OD1 . ASP A 1 292 ? 107.409 562.790 69.664 1.00 28.54 ? 346 ASP A OD1 1 ATOM 2053 O OD2 . ASP A 1 292 ? 107.121 564.073 71.426 1.00 39.91 ? 346 ASP A OD2 1 ATOM 2054 N N . ILE A 1 293 ? 111.266 563.254 67.995 1.00 28.73 ? 347 ILE A N 1 ATOM 2055 C CA . ILE A 1 293 ? 112.261 563.758 67.067 1.00 29.71 ? 347 ILE A CA 1 ATOM 2056 C C . ILE A 1 293 ? 111.601 564.823 66.217 1.00 37.95 ? 347 ILE A C 1 ATOM 2057 O O . ILE A 1 293 ? 110.539 564.580 65.660 1.00 38.25 ? 347 ILE A O 1 ATOM 2058 C CB . ILE A 1 293 ? 112.802 562.612 66.178 1.00 32.40 ? 347 ILE A CB 1 ATOM 2059 C CG1 . ILE A 1 293 ? 113.420 561.478 67.035 1.00 32.28 ? 347 ILE A CG1 1 ATOM 2060 C CG2 . ILE A 1 293 ? 113.795 563.176 65.162 1.00 33.08 ? 347 ILE A CG2 1 ATOM 2061 C CD1 . ILE A 1 293 ? 113.743 560.187 66.307 1.00 36.89 ? 347 ILE A CD1 1 ATOM 2062 N N . SER A 1 294 ? 112.229 565.980 66.082 1.00 37.05 ? 348 SER A N 1 ATOM 2063 C CA . SER A 1 294 ? 111.687 567.029 65.230 1.00 37.54 ? 348 SER A CA 1 ATOM 2064 C C . SER A 1 294 ? 112.809 567.763 64.506 1.00 44.77 ? 348 SER A C 1 ATOM 2065 O O . SER A 1 294 ? 113.935 567.769 64.978 1.00 43.13 ? 348 SER A O 1 ATOM 2066 C CB . SER A 1 294 ? 110.811 567.978 66.041 1.00 39.56 ? 348 SER A CB 1 ATOM 2067 O OG . SER A 1 294 ? 111.459 568.432 67.212 1.00 47.31 ? 348 SER A OG 1 ATOM 2068 N N . SER A 1 295 ? 112.528 568.364 63.356 1.00 45.99 ? 349 SER A N 1 ATOM 2069 C CA . SER A 1 295 ? 113.571 569.118 62.663 1.00 48.03 ? 349 SER A CA 1 ATOM 2070 C C . SER A 1 295 ? 113.148 570.581 62.424 1.00 58.62 ? 349 SER A C 1 ATOM 2071 O O . SER A 1 295 ? 112.030 570.961 62.787 1.00 58.89 ? 349 SER A O 1 ATOM 2072 C CB . SER A 1 295 ? 113.936 568.444 61.353 1.00 50.11 ? 349 SER A CB 1 ATOM 2073 O OG . SER A 1 295 ? 112.882 568.701 60.444 1.00 60.50 ? 349 SER A OG 1 ATOM 2074 N N . ASN A 1 296 ? 114.070 571.400 61.850 1.00 58.94 ? 350 ASN A N 1 ATOM 2075 C CA . ASN A 1 296 ? 113.910 572.823 61.470 1.00 59.77 ? 350 ASN A CA 1 ATOM 2076 C C . ASN A 1 296 ? 114.929 573.121 60.386 1.00 63.27 ? 350 ASN A C 1 ATOM 2077 O O . ASN A 1 296 ? 116.127 573.059 60.663 1.00 61.94 ? 350 ASN A O 1 ATOM 2078 C CB . ASN A 1 296 ? 114.150 573.823 62.637 1.00 64.00 ? 350 ASN A CB 1 ATOM 2079 C CG . ASN A 1 296 ? 114.253 573.237 64.017 1.00 101.44 ? 350 ASN A CG 1 ATOM 2080 O OD1 . ASN A 1 296 ? 115.346 572.981 64.527 1.00 99.55 ? 350 ASN A OD1 1 ATOM 2081 N ND2 . ASN A 1 296 ? 113.113 573.024 64.652 1.00 96.91 ? 350 ASN A ND2 1 ATOM 2082 N N . THR A 1 316 ? 122.110 575.835 58.889 1.00 55.32 ? 370 THR A N 1 ATOM 2083 C CA . THR A 1 316 ? 120.843 576.070 59.589 1.00 55.37 ? 370 THR A CA 1 ATOM 2084 C C . THR A 1 316 ? 119.994 574.774 59.815 1.00 55.59 ? 370 THR A C 1 ATOM 2085 O O . THR A 1 316 ? 119.139 574.838 60.717 1.00 54.81 ? 370 THR A O 1 ATOM 2086 C CB . THR A 1 316 ? 119.981 577.213 58.946 1.00 72.00 ? 370 THR A CB 1 ATOM 2087 O OG1 . THR A 1 316 ? 119.633 576.908 57.592 1.00 75.12 ? 370 THR A OG1 1 ATOM 2088 C CG2 . THR A 1 316 ? 120.634 578.590 59.047 1.00 72.36 ? 370 THR A CG2 1 ATOM 2089 N N . PRO A 1 317 ? 120.167 573.612 59.088 1.00 47.99 ? 371 PRO A N 1 ATOM 2090 C CA . PRO A 1 317 ? 119.357 572.421 59.438 1.00 45.36 ? 371 PRO A CA 1 ATOM 2091 C C . PRO A 1 317 ? 119.716 571.900 60.831 1.00 42.88 ? 371 PRO A C 1 ATOM 2092 O O . PRO A 1 317 ? 120.847 572.028 61.274 1.00 41.25 ? 371 PRO A O 1 ATOM 2093 C CB . PRO A 1 317 ? 119.677 571.414 58.344 1.00 47.39 ? 371 PRO A CB 1 ATOM 2094 C CG . PRO A 1 317 ? 121.001 571.802 57.822 1.00 52.64 ? 371 PRO A CG 1 ATOM 2095 C CD . PRO A 1 317 ? 121.133 573.297 58.012 1.00 49.13 ? 371 PRO A CD 1 ATOM 2096 N N . GLN A 1 318 ? 118.725 571.386 61.541 1.00 36.81 ? 372 GLN A N 1 ATOM 2097 C CA . GLN A 1 318 ? 118.850 570.980 62.928 1.00 35.10 ? 372 GLN A CA 1 ATOM 2098 C C . GLN A 1 318 ? 117.797 569.962 63.292 1.00 38.45 ? 372 GLN A C 1 ATOM 2099 O O . GLN A 1 318 ? 116.658 570.051 62.829 1.00 39.54 ? 372 GLN A O 1 ATOM 2100 C CB . GLN A 1 318 ? 118.668 572.219 63.805 1.00 35.51 ? 372 GLN A CB 1 ATOM 2101 C CG . GLN A 1 318 ? 118.744 571.959 65.292 1.00 37.70 ? 372 GLN A CG 1 ATOM 2102 C CD . GLN A 1 318 ? 118.730 573.240 66.064 1.00 45.52 ? 372 GLN A CD 1 ATOM 2103 O OE1 . GLN A 1 318 ? 117.845 573.484 66.887 1.00 37.85 ? 372 GLN A OE1 1 ATOM 2104 N NE2 . GLN A 1 318 ? 119.714 574.091 65.812 1.00 38.33 ? 372 GLN A NE2 1 ATOM 2105 N N . THR A 1 319 ? 118.183 568.992 64.134 1.00 32.97 ? 373 THR A N 1 ATOM 2106 C CA . THR A 1 319 ? 117.280 567.978 64.666 1.00 30.65 ? 373 THR A CA 1 ATOM 2107 C C . THR A 1 319 ? 117.264 568.129 66.171 1.00 33.09 ? 373 THR A C 1 ATOM 2108 O O . THR A 1 319 ? 118.309 568.313 66.802 1.00 32.90 ? 373 THR A O 1 ATOM 2109 C CB . THR A 1 319 ? 117.675 566.557 64.234 1.00 32.78 ? 373 THR A CB 1 ATOM 2110 O OG1 . THR A 1 319 ? 117.651 566.475 62.808 1.00 24.85 ? 373 THR A OG1 1 ATOM 2111 C CG2 . THR A 1 319 ? 116.717 565.499 64.768 1.00 31.18 ? 373 THR A CG2 1 ATOM 2112 N N . ASP A 1 320 ? 116.071 568.061 66.744 1.00 28.57 ? 374 ASP A N 1 ATOM 2113 C CA . ASP A 1 320 ? 115.874 568.115 68.182 1.00 26.55 ? 374 ASP A CA 1 ATOM 2114 C C . ASP A 1 320 ? 115.318 566.802 68.633 1.00 29.95 ? 374 ASP A C 1 ATOM 2115 O O . ASP A 1 320 ? 114.468 566.194 67.957 1.00 31.61 ? 374 ASP A O 1 ATOM 2116 C CB . ASP A 1 320 ? 114.961 569.274 68.583 1.00 27.88 ? 374 ASP A CB 1 ATOM 2117 C CG . ASP A 1 320 ? 115.427 570.634 68.082 1.00 40.43 ? 374 ASP A CG 1 ATOM 2118 O OD1 . ASP A 1 320 ? 116.640 570.896 68.121 1.00 39.69 ? 374 ASP A OD1 1 ATOM 2119 O OD2 . ASP A 1 320 ? 114.582 571.396 67.557 1.00 53.78 ? 374 ASP A OD2 1 ATOM 2120 N N . ILE A 1 321 ? 115.804 566.355 69.777 1.00 24.14 ? 375 ILE A N 1 ATOM 2121 C CA . ILE A 1 321 ? 115.439 565.067 70.353 1.00 22.62 ? 375 ILE A CA 1 ATOM 2122 C C . ILE A 1 321 ? 114.936 565.299 71.742 1.00 28.33 ? 375 ILE A C 1 ATOM 2123 O O . ILE A 1 321 ? 115.608 565.949 72.520 1.00 28.65 ? 375 ILE A O 1 ATOM 2124 C CB . ILE A 1 321 ? 116.686 564.118 70.427 1.00 23.79 ? 375 ILE A CB 1 ATOM 2125 C CG1 . ILE A 1 321 ? 117.458 564.001 69.098 1.00 21.33 ? 375 ILE A CG1 1 ATOM 2126 C CG2 . ILE A 1 321 ? 116.296 562.748 70.946 1.00 23.73 ? 375 ILE A CG2 1 ATOM 2127 C CD1 . ILE A 1 321 ? 116.702 563.378 67.985 1.00 10.74 ? 375 ILE A CD1 1 ATOM 2128 N N . ARG A 1 322 ? 113.825 564.700 72.096 1.00 25.92 ? 376 ARG A N 1 ATOM 2129 C CA . ARG A 1 322 ? 113.333 564.795 73.456 1.00 25.47 ? 376 ARG A CA 1 ATOM 2130 C C . ARG A 1 322 ? 113.106 563.390 74.032 1.00 28.03 ? 376 ARG A C 1 ATOM 2131 O O . ARG A 1 322 ? 112.450 562.564 73.409 1.00 26.84 ? 376 ARG A O 1 ATOM 2132 C CB . ARG A 1 322 ? 112.050 565.613 73.451 1.00 26.66 ? 376 ARG A CB 1 ATOM 2133 C CG . ARG A 1 322 ? 111.424 565.775 74.801 1.00 30.40 ? 376 ARG A CG 1 ATOM 2134 C CD . ARG A 1 322 ? 110.007 566.173 74.599 1.00 23.99 ? 376 ARG A CD 1 ATOM 2135 N NE . ARG A 1 322 ? 109.549 566.706 75.851 1.00 36.85 ? 376 ARG A NE 1 ATOM 2136 C CZ . ARG A 1 322 ? 108.414 567.351 76.011 1.00 47.10 ? 376 ARG A CZ 1 ATOM 2137 N NH1 . ARG A 1 322 ? 107.594 567.539 74.974 1.00 20.90 ? 376 ARG A NH1 1 ATOM 2138 N NH2 . ARG A 1 322 ? 108.080 567.816 77.205 1.00 33.65 ? 376 ARG A NH2 1 ATOM 2139 N N . TRP A 1 323 ? 113.611 563.145 75.232 1.00 25.73 ? 377 TRP A N 1 ATOM 2140 C CA . TRP A 1 323 ? 113.425 561.849 75.905 1.00 25.35 ? 377 TRP A CA 1 ATOM 2141 C C . TRP A 1 323 ? 112.477 562.038 77.091 1.00 28.11 ? 377 TRP A C 1 ATOM 2142 O O . TRP A 1 323 ? 112.602 563.013 77.829 1.00 28.29 ? 377 TRP A O 1 ATOM 2143 C CB . TRP A 1 323 ? 114.735 561.320 76.446 1.00 23.26 ? 377 TRP A CB 1 ATOM 2144 C CG . TRP A 1 323 ? 115.847 561.258 75.466 1.00 23.61 ? 377 TRP A CG 1 ATOM 2145 C CD1 . TRP A 1 323 ? 116.617 562.295 75.028 1.00 26.26 ? 377 TRP A CD1 1 ATOM 2146 C CD2 . TRP A 1 323 ? 116.366 560.077 74.849 1.00 23.39 ? 377 TRP A CD2 1 ATOM 2147 N NE1 . TRP A 1 323 ? 117.568 561.839 74.149 1.00 25.41 ? 377 TRP A NE1 1 ATOM 2148 C CE2 . TRP A 1 323 ? 117.450 560.474 74.036 1.00 27.50 ? 377 TRP A CE2 1 ATOM 2149 C CE3 . TRP A 1 323 ? 116.057 558.709 74.945 1.00 24.39 ? 377 TRP A CE3 1 ATOM 2150 C CZ2 . TRP A 1 323 ? 118.215 559.550 73.310 1.00 26.43 ? 377 TRP A CZ2 1 ATOM 2151 C CZ3 . TRP A 1 323 ? 116.814 557.800 74.228 1.00 25.42 ? 377 TRP A CZ3 1 ATOM 2152 C CH2 . TRP A 1 323 ? 117.881 558.221 73.424 1.00 26.04 ? 377 TRP A CH2 1 ATOM 2153 N N . MET A 1 324 ? 111.557 561.108 77.286 1.00 22.52 ? 378 MET A N 1 ATOM 2154 C CA . MET A 1 324 ? 110.570 561.215 78.355 1.00 22.78 ? 378 MET A CA 1 ATOM 2155 C C . MET A 1 324 ? 110.457 559.852 79.008 1.00 26.83 ? 378 MET A C 1 ATOM 2156 O O . MET A 1 324 ? 110.088 558.866 78.337 1.00 23.70 ? 378 MET A O 1 ATOM 2157 C CB . MET A 1 324 ? 109.221 561.668 77.758 1.00 24.96 ? 378 MET A CB 1 ATOM 2158 C CG . MET A 1 324 ? 109.309 563.007 77.029 1.00 27.80 ? 378 MET A CG 1 ATOM 2159 S SD . MET A 1 324 ? 107.851 563.352 76.043 1.00 31.21 ? 378 MET A SD 1 ATOM 2160 C CE . MET A 1 324 ? 108.213 562.489 74.566 1.00 26.89 ? 378 MET A CE 1 ATOM 2161 N N . SER A 1 325 ? 110.849 559.772 80.294 1.00 23.59 ? 379 SER A N 1 ATOM 2162 C CA . SER A 1 325 ? 110.862 558.513 81.019 1.00 22.08 ? 379 SER A CA 1 ATOM 2163 C C . SER A 1 325 ? 109.927 558.503 82.245 1.00 27.02 ? 379 SER A C 1 ATOM 2164 O O . SER A 1 325 ? 109.773 559.524 82.905 1.00 27.64 ? 379 SER A O 1 ATOM 2165 C CB . SER A 1 325 ? 112.291 558.154 81.380 1.00 23.69 ? 379 SER A CB 1 ATOM 2166 O OG . SER A 1 325 ? 113.072 557.956 80.214 1.00 27.26 ? 379 SER A OG 1 ATOM 2167 N N . GLU A 1 326 ? 109.289 557.360 82.541 1.00 23.11 ? 380 GLU A N 1 ATOM 2168 C CA . GLU A 1 326 ? 108.327 557.290 83.629 1.00 22.16 ? 380 GLU A CA 1 ATOM 2169 C C . GLU A 1 326 ? 108.873 557.573 85.005 1.00 26.88 ? 380 GLU A C 1 ATOM 2170 O O . GLU A 1 326 ? 108.145 558.112 85.842 1.00 27.46 ? 380 GLU A O 1 ATOM 2171 C CB . GLU A 1 326 ? 107.631 555.938 83.642 1.00 23.63 ? 380 GLU A CB 1 ATOM 2172 C CG . GLU A 1 326 ? 106.477 555.857 84.634 1.00 28.13 ? 380 GLU A CG 1 ATOM 2173 C CD . GLU A 1 326 ? 105.630 554.617 84.511 1.00 44.09 ? 380 GLU A CD 1 ATOM 2174 O OE1 . GLU A 1 326 ? 104.528 554.592 85.103 1.00 39.52 ? 380 GLU A OE1 1 ATOM 2175 O OE2 . GLU A 1 326 ? 106.045 553.681 83.792 1.00 42.74 ? 380 GLU A OE2 1 ATOM 2176 N N . SER A 1 327 ? 110.106 557.118 85.282 1.00 23.25 ? 381 SER A N 1 ATOM 2177 C CA . SER A 1 327 ? 110.705 557.212 86.606 1.00 21.24 ? 381 SER A CA 1 ATOM 2178 C C . SER A 1 327 ? 112.207 557.263 86.496 1.00 23.21 ? 381 SER A C 1 ATOM 2179 O O . SER A 1 327 ? 112.751 557.438 85.398 1.00 19.90 ? 381 SER A O 1 ATOM 2180 C CB . SER A 1 327 ? 110.224 556.062 87.499 1.00 23.74 ? 381 SER A CB 1 ATOM 2181 O OG . SER A 1 327 ? 110.869 554.825 87.224 1.00 33.34 ? 381 SER A OG 1 ATOM 2182 N N . GLY A 1 328 ? 112.860 557.185 87.649 1.00 22.50 ? 382 GLY A N 1 ATOM 2183 C CA . GLY A 1 328 ? 114.306 557.283 87.750 1.00 23.56 ? 382 GLY A CA 1 ATOM 2184 C C . GLY A 1 328 ? 114.814 558.716 87.710 1.00 30.69 ? 382 GLY A C 1 ATOM 2185 O O . GLY A 1 328 ? 114.055 559.679 87.899 1.00 34.20 ? 382 GLY A O 1 ATOM 2186 N N . ILE A 1 329 ? 116.106 558.861 87.474 1.00 23.19 ? 383 ILE A N 1 ATOM 2187 C CA . ILE A 1 329 ? 116.720 560.174 87.370 1.00 22.15 ? 383 ILE A CA 1 ATOM 2188 C C . ILE A 1 329 ? 116.944 560.470 85.913 1.00 26.69 ? 383 ILE A C 1 ATOM 2189 O O . ILE A 1 329 ? 116.698 559.618 85.043 1.00 27.05 ? 383 ILE A O 1 ATOM 2190 C CB . ILE A 1 329 ? 118.060 560.260 88.180 1.00 23.95 ? 383 ILE A CB 1 ATOM 2191 C CG1 . ILE A 1 329 ? 119.171 559.372 87.563 1.00 24.07 ? 383 ILE A CG1 1 ATOM 2192 C CG2 . ILE A 1 329 ? 117.809 559.955 89.655 1.00 21.24 ? 383 ILE A CG2 1 ATOM 2193 C CD1 . ILE A 1 329 ? 120.562 559.717 87.959 1.00 26.98 ? 383 ILE A CD1 1 ATOM 2194 N N . ILE A 1 330 ? 117.419 561.674 85.654 1.00 22.94 ? 384 ILE A N 1 ATOM 2195 C CA . ILE A 1 330 ? 117.917 562.043 84.355 1.00 23.28 ? 384 ILE A CA 1 ATOM 2196 C C . ILE A 1 330 ? 119.395 561.695 84.442 1.00 28.74 ? 384 ILE A C 1 ATOM 2197 O O . ILE A 1 330 ? 120.106 562.189 85.324 1.00 28.84 ? 384 ILE A O 1 ATOM 2198 C CB . ILE A 1 330 ? 117.724 563.530 84.047 1.00 25.87 ? 384 ILE A CB 1 ATOM 2199 C CG1 . ILE A 1 330 ? 116.239 563.821 83.838 1.00 26.47 ? 384 ILE A CG1 1 ATOM 2200 C CG2 . ILE A 1 330 ? 118.571 563.916 82.815 1.00 24.75 ? 384 ILE A CG2 1 ATOM 2201 C CD1 . ILE A 1 330 ? 115.932 565.254 83.598 1.00 34.64 ? 384 ILE A CD1 1 ATOM 2202 N N . ASP A 1 331 ? 119.838 560.819 83.553 1.00 24.73 ? 385 ASP A N 1 ATOM 2203 C CA . ASP A 1 331 ? 121.228 560.400 83.470 1.00 24.03 ? 385 ASP A CA 1 ATOM 2204 C C . ASP A 1 331 ? 121.516 560.247 81.983 1.00 26.85 ? 385 ASP A C 1 ATOM 2205 O O . ASP A 1 331 ? 121.027 559.326 81.316 1.00 26.84 ? 385 ASP A O 1 ATOM 2206 C CB . ASP A 1 331 ? 121.475 559.086 84.247 1.00 25.19 ? 385 ASP A CB 1 ATOM 2207 C CG . ASP A 1 331 ? 122.950 558.685 84.362 1.00 29.03 ? 385 ASP A CG 1 ATOM 2208 O OD1 . ASP A 1 331 ? 123.810 559.408 83.823 1.00 30.41 ? 385 ASP A OD1 1 ATOM 2209 O OD2 . ASP A 1 331 ? 123.236 557.648 84.989 1.00 32.78 ? 385 ASP A OD2 1 ATOM 2210 N N . VAL A 1 332 ? 122.245 561.185 81.451 1.00 22.98 ? 386 VAL A N 1 ATOM 2211 C CA . VAL A 1 332 ? 122.499 561.171 80.020 1.00 23.25 ? 386 VAL A CA 1 ATOM 2212 C C . VAL A 1 332 ? 123.969 561.392 79.710 1.00 24.43 ? 386 VAL A C 1 ATOM 2213 O O . VAL A 1 332 ? 124.609 562.239 80.318 1.00 24.58 ? 386 VAL A O 1 ATOM 2214 C CB . VAL A 1 332 ? 121.552 562.164 79.279 1.00 26.81 ? 386 VAL A CB 1 ATOM 2215 C CG1 . VAL A 1 332 ? 121.816 563.599 79.702 1.00 26.79 ? 386 VAL A CG1 1 ATOM 2216 C CG2 . VAL A 1 332 ? 121.641 562.020 77.754 1.00 26.68 ? 386 VAL A CG2 1 ATOM 2217 N N . PHE A 1 333 ? 124.484 560.618 78.775 1.00 19.64 ? 387 PHE A N 1 ATOM 2218 C CA . PHE A 1 333 ? 125.835 560.738 78.269 1.00 19.39 ? 387 PHE A CA 1 ATOM 2219 C C . PHE A 1 333 ? 125.778 561.353 76.859 1.00 24.36 ? 387 PHE A C 1 ATOM 2220 O O . PHE A 1 333 ? 124.982 560.943 76.003 1.00 25.36 ? 387 PHE A O 1 ATOM 2221 C CB . PHE A 1 333 ? 126.506 559.360 78.223 1.00 21.14 ? 387 PHE A CB 1 ATOM 2222 C CG . PHE A 1 333 ? 126.800 558.752 79.574 1.00 22.38 ? 387 PHE A CG 1 ATOM 2223 C CD1 . PHE A 1 333 ? 125.861 557.949 80.211 1.00 25.64 ? 387 PHE A CD1 1 ATOM 2224 C CD2 . PHE A 1 333 ? 128.042 558.926 80.175 1.00 23.43 ? 387 PHE A CD2 1 ATOM 2225 C CE1 . PHE A 1 333 ? 126.146 557.362 81.451 1.00 25.94 ? 387 PHE A CE1 1 ATOM 2226 C CE2 . PHE A 1 333 ? 128.337 558.319 81.388 1.00 26.33 ? 387 PHE A CE2 1 ATOM 2227 C CZ . PHE A 1 333 ? 127.382 557.548 82.025 1.00 24.60 ? 387 PHE A CZ 1 ATOM 2228 N N . LEU A 1 334 ? 126.592 562.373 76.634 1.00 20.48 ? 388 LEU A N 1 ATOM 2229 C CA . LEU A 1 334 ? 126.719 563.010 75.332 1.00 19.34 ? 388 LEU A CA 1 ATOM 2230 C C . LEU A 1 334 ? 128.091 562.595 74.880 1.00 24.46 ? 388 LEU A C 1 ATOM 2231 O O . LEU A 1 334 ? 129.056 562.724 75.617 1.00 26.00 ? 388 LEU A O 1 ATOM 2232 C CB . LEU A 1 334 ? 126.549 564.520 75.469 1.00 19.53 ? 388 LEU A CB 1 ATOM 2233 C CG . LEU A 1 334 ? 125.237 564.857 76.202 1.00 24.50 ? 388 LEU A CG 1 ATOM 2234 C CD1 . LEU A 1 334 ? 125.147 566.265 76.588 1.00 26.73 ? 388 LEU A CD1 1 ATOM 2235 C CD2 . LEU A 1 334 ? 124.032 564.478 75.376 1.00 23.42 ? 388 LEU A CD2 1 ATOM 2236 N N . MET A 1 335 ? 128.148 561.928 73.748 1.00 19.07 ? 389 MET A N 1 ATOM 2237 C CA . MET A 1 335 ? 129.340 561.319 73.191 1.00 16.50 ? 389 MET A CA 1 ATOM 2238 C C . MET A 1 335 ? 129.670 562.130 71.974 1.00 23.18 ? 389 MET A C 1 ATOM 2239 O O . MET A 1 335 ? 128.916 562.132 70.985 1.00 23.22 ? 389 MET A O 1 ATOM 2240 C CB . MET A 1 335 ? 129.029 559.849 72.897 1.00 18.72 ? 389 MET A CB 1 ATOM 2241 C CG . MET A 1 335 ? 128.542 559.101 74.138 1.00 21.78 ? 389 MET A CG 1 ATOM 2242 S SD . MET A 1 335 ? 128.185 557.375 73.912 1.00 25.69 ? 389 MET A SD 1 ATOM 2243 C CE . MET A 1 335 ? 126.649 557.480 72.962 1.00 22.45 ? 389 MET A CE 1 ATOM 2244 N N . LEU A 1 336 ? 130.758 562.912 72.073 1.00 21.03 ? 390 LEU A N 1 ATOM 2245 C CA . LEU A 1 336 ? 131.002 563.977 71.115 1.00 20.74 ? 390 LEU A CA 1 ATOM 2246 C C . LEU A 1 336 ? 131.837 563.639 69.899 1.00 27.62 ? 390 LEU A C 1 ATOM 2247 O O . LEU A 1 336 ? 132.143 564.545 69.100 1.00 26.45 ? 390 LEU A O 1 ATOM 2248 C CB . LEU A 1 336 ? 131.569 565.211 71.849 1.00 19.88 ? 390 LEU A CB 1 ATOM 2249 C CG . LEU A 1 336 ? 130.721 565.669 73.054 1.00 21.41 ? 390 LEU A CG 1 ATOM 2250 C CD1 . LEU A 1 336 ? 131.324 566.852 73.668 1.00 22.14 ? 390 LEU A CD1 1 ATOM 2251 C CD2 . LEU A 1 336 ? 129.271 565.943 72.678 1.00 15.69 ? 390 LEU A CD2 1 ATOM 2252 N N . GLY A 1 337 ? 132.120 562.356 69.692 1.00 26.11 ? 391 GLY A N 1 ATOM 2253 C CA . GLY A 1 337 ? 132.868 561.967 68.510 1.00 25.36 ? 391 GLY A CA 1 ATOM 2254 C C . GLY A 1 337 ? 134.305 562.447 68.536 1.00 28.86 ? 391 GLY A C 1 ATOM 2255 O O . GLY A 1 337 ? 134.985 562.273 69.552 1.00 27.77 ? 391 GLY A O 1 ATOM 2256 N N . PRO A 1 338 ? 134.807 563.061 67.438 1.00 27.22 ? 392 PRO A N 1 ATOM 2257 C CA . PRO A 1 338 ? 134.068 563.559 66.264 1.00 26.47 ? 392 PRO A CA 1 ATOM 2258 C C . PRO A 1 338 ? 133.698 562.572 65.172 1.00 29.70 ? 392 PRO A C 1 ATOM 2259 O O . PRO A 1 338 ? 132.752 562.860 64.463 1.00 30.60 ? 392 PRO A O 1 ATOM 2260 C CB . PRO A 1 338 ? 134.991 564.646 65.727 1.00 28.27 ? 392 PRO A CB 1 ATOM 2261 C CG . PRO A 1 338 ? 136.355 564.135 66.045 1.00 32.75 ? 392 PRO A CG 1 ATOM 2262 C CD . PRO A 1 338 ? 136.201 563.552 67.418 1.00 28.65 ? 392 PRO A CD 1 ATOM 2263 N N . SER A 1 339 ? 134.410 561.450 65.009 1.00 25.87 ? 393 SER A N 1 ATOM 2264 C CA . SER A 1 339 ? 134.027 560.449 63.997 1.00 24.65 ? 393 SER A CA 1 ATOM 2265 C C . SER A 1 339 ? 133.043 559.411 64.590 1.00 29.53 ? 393 SER A C 1 ATOM 2266 O O . SER A 1 339 ? 132.879 559.308 65.809 1.00 30.00 ? 393 SER A O 1 ATOM 2267 C CB . SER A 1 339 ? 135.245 559.735 63.423 1.00 24.41 ? 393 SER A CB 1 ATOM 2268 O OG . SER A 1 339 ? 135.563 558.593 64.201 1.00 30.65 ? 393 SER A OG 1 ATOM 2269 N N . VAL A 1 340 ? 132.405 558.627 63.727 1.00 25.66 ? 394 VAL A N 1 ATOM 2270 C CA . VAL A 1 340 ? 131.462 557.636 64.203 1.00 24.74 ? 394 VAL A CA 1 ATOM 2271 C C . VAL A 1 340 ? 132.209 556.531 64.964 1.00 27.36 ? 394 VAL A C 1 ATOM 2272 O O . VAL A 1 340 ? 131.690 555.994 65.947 1.00 25.74 ? 394 VAL A O 1 ATOM 2273 C CB . VAL A 1 340 ? 130.550 557.116 63.079 1.00 28.12 ? 394 VAL A CB 1 ATOM 2274 C CG1 . VAL A 1 340 ? 131.293 556.180 62.147 1.00 27.98 ? 394 VAL A CG1 1 ATOM 2275 C CG2 . VAL A 1 340 ? 129.319 556.452 63.664 1.00 27.88 ? 394 VAL A CG2 1 ATOM 2276 N N . PHE A 1 341 ? 133.458 556.247 64.553 1.00 21.72 ? 395 PHE A N 1 ATOM 2277 C CA . PHE A 1 341 ? 134.286 555.271 65.238 1.00 19.11 ? 395 PHE A CA 1 ATOM 2278 C C . PHE A 1 341 ? 134.647 555.736 66.635 1.00 23.98 ? 395 PHE A C 1 ATOM 2279 O O . PHE A 1 341 ? 134.686 554.922 67.556 1.00 25.45 ? 395 PHE A O 1 ATOM 2280 C CB . PHE A 1 341 ? 135.510 554.918 64.405 1.00 20.16 ? 395 PHE A CB 1 ATOM 2281 C CG . PHE A 1 341 ? 135.124 554.056 63.234 1.00 21.58 ? 395 PHE A CG 1 ATOM 2282 C CD1 . PHE A 1 341 ? 134.909 552.691 63.397 1.00 23.94 ? 395 PHE A CD1 1 ATOM 2283 C CD2 . PHE A 1 341 ? 134.850 554.620 61.999 1.00 23.44 ? 395 PHE A CD2 1 ATOM 2284 C CE1 . PHE A 1 341 ? 134.470 551.897 62.333 1.00 23.64 ? 395 PHE A CE1 1 ATOM 2285 C CE2 . PHE A 1 341 ? 134.425 553.821 60.935 1.00 26.37 ? 395 PHE A CE2 1 ATOM 2286 C CZ . PHE A 1 341 ? 134.251 552.459 61.110 1.00 23.39 ? 395 PHE A CZ 1 ATOM 2287 N N . ASP A 1 342 ? 134.861 557.050 66.813 1.00 19.41 ? 396 ASP A N 1 ATOM 2288 C CA . ASP A 1 342 ? 135.094 557.668 68.119 1.00 17.89 ? 396 ASP A CA 1 ATOM 2289 C C . ASP A 1 342 ? 133.861 557.503 69.005 1.00 20.15 ? 396 ASP A C 1 ATOM 2290 O O . ASP A 1 342 ? 134.009 557.148 70.161 1.00 19.04 ? 396 ASP A O 1 ATOM 2291 C CB . ASP A 1 342 ? 135.435 559.157 67.978 1.00 19.83 ? 396 ASP A CB 1 ATOM 2292 C CG . ASP A 1 342 ? 136.684 559.467 67.169 1.00 28.13 ? 396 ASP A CG 1 ATOM 2293 O OD1 . ASP A 1 342 ? 137.657 558.661 67.228 1.00 29.25 ? 396 ASP A OD1 1 ATOM 2294 O OD2 . ASP A 1 342 ? 136.707 560.524 66.509 1.00 28.55 ? 396 ASP A OD2 1 ATOM 2295 N N . VAL A 1 343 ? 132.650 557.700 68.453 1.00 17.58 ? 397 VAL A N 1 ATOM 2296 C CA . VAL A 1 343 ? 131.388 557.508 69.186 1.00 16.17 ? 397 VAL A CA 1 ATOM 2297 C C . VAL A 1 343 ? 131.249 556.018 69.571 1.00 20.86 ? 397 VAL A C 1 ATOM 2298 O O . VAL A 1 343 ? 130.914 555.735 70.732 1.00 19.61 ? 397 VAL A O 1 ATOM 2299 C CB . VAL A 1 343 ? 130.170 558.011 68.369 1.00 18.63 ? 397 VAL A CB 1 ATOM 2300 C CG1 . VAL A 1 343 ? 128.848 557.647 69.041 1.00 18.52 ? 397 VAL A CG1 1 ATOM 2301 C CG2 . VAL A 1 343 ? 130.248 559.507 68.086 1.00 17.42 ? 397 VAL A CG2 1 ATOM 2302 N N . PHE A 1 344 ? 131.556 555.067 68.633 1.00 16.30 ? 398 PHE A N 1 ATOM 2303 C CA . PHE A 1 344 ? 131.495 553.638 68.963 1.00 15.82 ? 398 PHE A CA 1 ATOM 2304 C C . PHE A 1 344 ? 132.395 553.322 70.147 1.00 25.40 ? 398 PHE A C 1 ATOM 2305 O O . PHE A 1 344 ? 131.960 552.630 71.071 1.00 25.78 ? 398 PHE A O 1 ATOM 2306 C CB . PHE A 1 344 ? 131.897 552.750 67.794 1.00 16.56 ? 398 PHE A CB 1 ATOM 2307 C CG . PHE A 1 344 ? 131.027 552.800 66.563 1.00 17.13 ? 398 PHE A CG 1 ATOM 2308 C CD1 . PHE A 1 344 ? 129.651 552.963 66.664 1.00 17.84 ? 398 PHE A CD1 1 ATOM 2309 C CD2 . PHE A 1 344 ? 131.589 552.673 65.290 1.00 20.37 ? 398 PHE A CD2 1 ATOM 2310 C CE1 . PHE A 1 344 ? 128.847 552.997 65.513 1.00 18.83 ? 398 PHE A CE1 1 ATOM 2311 C CE2 . PHE A 1 344 ? 130.790 552.728 64.137 1.00 22.24 ? 398 PHE A CE2 1 ATOM 2312 C CZ . PHE A 1 344 ? 129.418 552.879 64.257 1.00 19.35 ? 398 PHE A CZ 1 ATOM 2313 N N . ARG A 1 345 ? 133.619 553.873 70.158 1.00 24.47 ? 399 ARG A N 1 ATOM 2314 C CA . ARG A 1 345 ? 134.563 553.649 71.259 1.00 24.50 ? 399 ARG A CA 1 ATOM 2315 C C . ARG A 1 345 ? 134.051 554.238 72.559 1.00 28.48 ? 399 ARG A C 1 ATOM 2316 O O . ARG A 1 345 ? 134.229 553.643 73.621 1.00 31.07 ? 399 ARG A O 1 ATOM 2317 C CB . ARG A 1 345 ? 135.922 554.292 70.965 1.00 25.59 ? 399 ARG A CB 1 ATOM 2318 C CG . ARG A 1 345 ? 136.820 553.538 70.044 1.00 39.22 ? 399 ARG A CG 1 ATOM 2319 C CD . ARG A 1 345 ? 138.243 554.019 70.179 1.00 51.98 ? 399 ARG A CD 1 ATOM 2320 N NE . ARG A 1 345 ? 139.133 553.181 69.383 1.00 67.71 ? 399 ARG A NE 1 ATOM 2321 C CZ . ARG A 1 345 ? 139.476 553.435 68.124 1.00 85.17 ? 399 ARG A CZ 1 ATOM 2322 N NH1 . ARG A 1 345 ? 139.016 554.519 67.509 1.00 69.04 ? 399 ARG A NH1 1 ATOM 2323 N NH2 . ARG A 1 345 ? 140.285 552.609 67.471 1.00 73.10 ? 399 ARG A NH2 1 ATOM 2324 N N . GLN A 1 346 ? 133.496 555.442 72.487 1.00 20.72 ? 400 GLN A N 1 ATOM 2325 C CA . GLN A 1 346 ? 132.986 556.161 73.636 1.00 18.98 ? 400 GLN A CA 1 ATOM 2326 C C . GLN A 1 346 ? 131.902 555.326 74.302 1.00 23.39 ? 400 GLN A C 1 ATOM 2327 O O . GLN A 1 346 ? 131.947 555.062 75.507 1.00 22.85 ? 400 GLN A O 1 ATOM 2328 C CB . GLN A 1 346 ? 132.440 557.535 73.188 1.00 19.60 ? 400 GLN A CB 1 ATOM 2329 C CG . GLN A 1 346 ? 133.565 558.516 72.925 1.00 22.26 ? 400 GLN A CG 1 ATOM 2330 C CD . GLN A 1 346 ? 133.316 559.609 71.906 1.00 34.40 ? 400 GLN A CD 1 ATOM 2331 O OE1 . GLN A 1 346 ? 132.183 559.911 71.512 1.00 36.08 ? 400 GLN A OE1 1 ATOM 2332 N NE2 . GLN A 1 346 ? 134.400 560.247 71.461 1.00 20.26 ? 400 GLN A NE2 1 ATOM 2333 N N . TYR A 1 347 ? 130.928 554.907 73.509 1.00 21.15 ? 401 TYR A N 1 ATOM 2334 C CA . TYR A 1 347 ? 129.839 554.075 74.002 1.00 20.83 ? 401 TYR A CA 1 ATOM 2335 C C . TYR A 1 347 ? 130.319 552.716 74.526 1.00 26.04 ? 401 TYR A C 1 ATOM 2336 O O . TYR A 1 347 ? 129.837 552.295 75.567 1.00 26.62 ? 401 TYR A O 1 ATOM 2337 C CB . TYR A 1 347 ? 128.763 553.927 72.935 1.00 20.22 ? 401 TYR A CB 1 ATOM 2338 C CG . TYR A 1 347 ? 127.586 553.141 73.423 1.00 19.42 ? 401 TYR A CG 1 ATOM 2339 C CD1 . TYR A 1 347 ? 126.746 553.648 74.408 1.00 20.72 ? 401 TYR A CD1 1 ATOM 2340 C CD2 . TYR A 1 347 ? 127.344 551.855 72.950 1.00 18.68 ? 401 TYR A CD2 1 ATOM 2341 C CE1 . TYR A 1 347 ? 125.689 552.897 74.906 1.00 20.41 ? 401 TYR A CE1 1 ATOM 2342 C CE2 . TYR A 1 347 ? 126.269 551.115 73.409 1.00 19.04 ? 401 TYR A CE2 1 ATOM 2343 C CZ . TYR A 1 347 ? 125.450 551.635 74.392 1.00 23.40 ? 401 TYR A CZ 1 ATOM 2344 O OH . TYR A 1 347 ? 124.401 550.888 74.839 1.00 18.46 ? 401 TYR A OH 1 ATOM 2345 N N . ALA A 1 348 ? 131.280 552.055 73.849 1.00 23.61 ? 402 ALA A N 1 ATOM 2346 C CA . ALA A 1 348 ? 131.824 550.768 74.305 1.00 23.54 ? 402 ALA A CA 1 ATOM 2347 C C . ALA A 1 348 ? 132.592 550.941 75.629 1.00 26.31 ? 402 ALA A C 1 ATOM 2348 O O . ALA A 1 348 ? 132.601 550.045 76.472 1.00 25.21 ? 402 ALA A O 1 ATOM 2349 C CB . ALA A 1 348 ? 132.732 550.172 73.240 1.00 24.32 ? 402 ALA A CB 1 ATOM 2350 N N . SER A 1 349 ? 133.200 552.107 75.831 1.00 22.62 ? 403 SER A N 1 ATOM 2351 C CA . SER A 1 349 ? 133.891 552.375 77.088 1.00 22.42 ? 403 SER A CA 1 ATOM 2352 C C . SER A 1 349 ? 132.881 552.432 78.247 1.00 27.81 ? 403 SER A C 1 ATOM 2353 O O . SER A 1 349 ? 133.249 552.150 79.396 1.00 28.89 ? 403 SER A O 1 ATOM 2354 C CB . SER A 1 349 ? 134.736 553.651 77.003 1.00 24.85 ? 403 SER A CB 1 ATOM 2355 O OG . SER A 1 349 ? 133.975 554.836 77.191 1.00 32.13 ? 403 SER A OG 1 ATOM 2356 N N . LEU A 1 350 ? 131.609 552.762 77.948 1.00 21.65 ? 404 LEU A N 1 ATOM 2357 C CA . LEU A 1 350 ? 130.582 552.850 78.979 1.00 19.87 ? 404 LEU A CA 1 ATOM 2358 C C . LEU A 1 350 ? 129.907 551.534 79.222 1.00 21.65 ? 404 LEU A C 1 ATOM 2359 O O . LEU A 1 350 ? 129.734 551.163 80.378 1.00 19.73 ? 404 LEU A O 1 ATOM 2360 C CB . LEU A 1 350 ? 129.505 553.894 78.595 1.00 19.37 ? 404 LEU A CB 1 ATOM 2361 C CG . LEU A 1 350 ? 129.955 555.355 78.418 1.00 22.89 ? 404 LEU A CG 1 ATOM 2362 C CD1 . LEU A 1 350 ? 128.809 556.236 77.962 1.00 20.52 ? 404 LEU A CD1 1 ATOM 2363 C CD2 . LEU A 1 350 ? 130.650 555.890 79.669 1.00 21.52 ? 404 LEU A CD2 1 ATOM 2364 N N . THR A 1 351 ? 129.473 550.847 78.153 1.00 19.05 ? 405 THR A N 1 ATOM 2365 C CA . THR A 1 351 ? 128.639 549.627 78.281 1.00 20.74 ? 405 THR A CA 1 ATOM 2366 C C . THR A 1 351 ? 129.289 548.327 77.877 1.00 26.76 ? 405 THR A C 1 ATOM 2367 O O . THR A 1 351 ? 128.660 547.281 77.984 1.00 27.45 ? 405 THR A O 1 ATOM 2368 C CB . THR A 1 351 ? 127.306 549.781 77.521 1.00 24.79 ? 405 THR A CB 1 ATOM 2369 O OG1 . THR A 1 351 ? 127.538 549.816 76.108 1.00 22.77 ? 405 THR A OG1 1 ATOM 2370 C CG2 . THR A 1 351 ? 126.555 551.014 77.950 1.00 21.66 ? 405 THR A CG2 1 ATOM 2371 N N . GLY A 1 352 ? 130.540 548.390 77.448 1.00 23.66 ? 406 GLY A N 1 ATOM 2372 C CA . GLY A 1 352 ? 131.268 547.208 77.022 1.00 21.95 ? 406 GLY A CA 1 ATOM 2373 C C . GLY A 1 352 ? 131.065 546.870 75.569 1.00 25.41 ? 406 GLY A C 1 ATOM 2374 O O . GLY A 1 352 ? 130.426 547.604 74.804 1.00 24.14 ? 406 GLY A O 1 ATOM 2375 N N . THR A 1 353 ? 131.657 545.750 75.184 1.00 22.19 ? 407 THR A N 1 ATOM 2376 C CA . THR A 1 353 ? 131.664 545.320 73.811 1.00 21.74 ? 407 THR A CA 1 ATOM 2377 C C . THR A 1 353 ? 130.966 544.018 73.609 1.00 25.73 ? 407 THR A C 1 ATOM 2378 O O . THR A 1 353 ? 130.721 543.267 74.552 1.00 27.10 ? 407 THR A O 1 ATOM 2379 C CB . THR A 1 353 ? 133.117 545.184 73.339 1.00 25.79 ? 407 THR A CB 1 ATOM 2380 O OG1 . THR A 1 353 ? 133.762 544.216 74.172 1.00 26.49 ? 407 THR A OG1 1 ATOM 2381 C CG2 . THR A 1 353 ? 133.871 546.494 73.390 1.00 20.56 ? 407 THR A CG2 1 ATOM 2382 N N . GLN A 1 354 ? 130.691 543.729 72.350 1.00 21.03 ? 408 GLN A N 1 ATOM 2383 C CA . GLN A 1 354 ? 130.124 542.476 71.949 1.00 19.31 ? 408 GLN A CA 1 ATOM 2384 C C . GLN A 1 354 ? 130.959 541.286 72.476 1.00 21.13 ? 408 GLN A C 1 ATOM 2385 O O . GLN A 1 354 ? 132.166 541.225 72.255 1.00 18.52 ? 408 GLN A O 1 ATOM 2386 C CB . GLN A 1 354 ? 130.044 542.433 70.426 1.00 19.22 ? 408 GLN A CB 1 ATOM 2387 C CG . GLN A 1 354 ? 129.521 541.092 69.908 1.00 23.66 ? 408 GLN A CG 1 ATOM 2388 C CD . GLN A 1 354 ? 128.109 540.851 70.326 1.00 32.90 ? 408 GLN A CD 1 ATOM 2389 O OE1 . GLN A 1 354 ? 127.247 541.721 70.169 1.00 26.95 ? 408 GLN A OE1 1 ATOM 2390 N NE2 . GLN A 1 354 ? 127.834 539.657 70.822 1.00 29.55 ? 408 GLN A NE2 1 ATOM 2391 N N . ALA A 1 355 ? 130.290 540.342 73.167 1.00 19.68 ? 409 ALA A N 1 ATOM 2392 C CA . ALA A 1 355 ? 130.918 539.118 73.654 1.00 19.25 ? 409 ALA A CA 1 ATOM 2393 C C . ALA A 1 355 ? 131.362 538.343 72.432 1.00 22.90 ? 409 ALA A C 1 ATOM 2394 O O . ALA A 1 355 ? 130.645 538.323 71.435 1.00 25.62 ? 409 ALA A O 1 ATOM 2395 C CB . ALA A 1 355 ? 129.922 538.309 74.439 1.00 20.30 ? 409 ALA A CB 1 ATOM 2396 N N . LEU A 1 356 ? 132.555 537.751 72.473 1.00 18.73 ? 410 LEU A N 1 ATOM 2397 C CA . LEU A 1 356 ? 133.125 537.014 71.343 1.00 17.53 ? 410 LEU A CA 1 ATOM 2398 C C . LEU A 1 356 ? 132.370 535.709 71.181 1.00 24.80 ? 410 LEU A C 1 ATOM 2399 O O . LEU A 1 356 ? 132.442 534.829 72.063 1.00 22.98 ? 410 LEU A O 1 ATOM 2400 C CB . LEU A 1 356 ? 134.615 536.745 71.544 1.00 16.84 ? 410 LEU A CB 1 ATOM 2401 C CG . LEU A 1 356 ? 135.306 536.032 70.419 1.00 19.81 ? 410 LEU A CG 1 ATOM 2402 C CD1 . LEU A 1 356 ? 135.320 536.914 69.178 1.00 19.30 ? 410 LEU A CD1 1 ATOM 2403 C CD2 . LEU A 1 356 ? 136.693 535.631 70.825 1.00 20.45 ? 410 LEU A CD2 1 ATOM 2404 N N . PRO A 1 357 ? 131.600 535.557 70.085 1.00 23.27 ? 411 PRO A N 1 ATOM 2405 C CA . PRO A 1 357 ? 130.835 534.332 69.960 1.00 23.17 ? 411 PRO A CA 1 ATOM 2406 C C . PRO A 1 357 ? 131.714 533.119 69.785 1.00 25.88 ? 411 PRO A C 1 ATOM 2407 O O . PRO A 1 357 ? 132.691 533.186 69.034 1.00 24.64 ? 411 PRO A O 1 ATOM 2408 C CB . PRO A 1 357 ? 130.009 534.547 68.678 1.00 25.28 ? 411 PRO A CB 1 ATOM 2409 C CG . PRO A 1 357 ? 130.069 535.988 68.376 1.00 29.52 ? 411 PRO A CG 1 ATOM 2410 C CD . PRO A 1 357 ? 131.397 536.431 68.913 1.00 25.18 ? 411 PRO A CD 1 ATOM 2411 N N . PRO A 1 358 ? 131.351 531.969 70.389 1.00 22.11 ? 412 PRO A N 1 ATOM 2412 C CA . PRO A 1 358 ? 132.032 530.727 69.993 1.00 20.99 ? 412 PRO A CA 1 ATOM 2413 C C . PRO A 1 358 ? 131.787 530.562 68.491 1.00 25.86 ? 412 PRO A C 1 ATOM 2414 O O . PRO A 1 358 ? 130.724 530.937 67.986 1.00 29.24 ? 412 PRO A O 1 ATOM 2415 C CB . PRO A 1 358 ? 131.339 529.639 70.806 1.00 22.40 ? 412 PRO A CB 1 ATOM 2416 C CG . PRO A 1 358 ? 130.113 530.257 71.340 1.00 27.24 ? 412 PRO A CG 1 ATOM 2417 C CD . PRO A 1 358 ? 130.254 531.732 71.344 1.00 22.22 ? 412 PRO A CD 1 ATOM 2418 N N . LEU A 1 359 ? 132.778 530.076 67.763 1.00 20.09 ? 413 LEU A N 1 ATOM 2419 C CA . LEU A 1 359 ? 132.678 530.000 66.318 1.00 19.27 ? 413 LEU A CA 1 ATOM 2420 C C . LEU A 1 359 ? 131.413 529.301 65.796 1.00 23.98 ? 413 LEU A C 1 ATOM 2421 O O . LEU A 1 359 ? 130.850 529.751 64.796 1.00 24.56 ? 413 LEU A O 1 ATOM 2422 C CB . LEU A 1 359 ? 133.946 529.372 65.746 1.00 18.58 ? 413 LEU A CB 1 ATOM 2423 C CG . LEU A 1 359 ? 134.044 529.210 64.245 1.00 22.25 ? 413 LEU A CG 1 ATOM 2424 C CD1 . LEU A 1 359 ? 134.166 530.539 63.542 1.00 22.01 ? 413 LEU A CD1 1 ATOM 2425 C CD2 . LEU A 1 359 ? 135.214 528.351 63.894 1.00 24.48 ? 413 LEU A CD2 1 ATOM 2426 N N . PHE A 1 360 ? 130.980 528.223 66.448 1.00 19.84 ? 414 PHE A N 1 ATOM 2427 C CA . PHE A 1 360 ? 129.823 527.475 65.945 1.00 19.77 ? 414 PHE A CA 1 ATOM 2428 C C . PHE A 1 360 ? 128.591 528.339 65.821 1.00 25.79 ? 414 PHE A C 1 ATOM 2429 O O . PHE A 1 360 ? 127.759 528.090 64.951 1.00 26.49 ? 414 PHE A O 1 ATOM 2430 C CB . PHE A 1 360 ? 129.530 526.220 66.794 1.00 19.98 ? 414 PHE A CB 1 ATOM 2431 C CG . PHE A 1 360 ? 128.879 526.524 68.109 1.00 20.73 ? 414 PHE A CG 1 ATOM 2432 C CD1 . PHE A 1 360 ? 127.523 526.764 68.187 1.00 24.35 ? 414 PHE A CD1 1 ATOM 2433 C CD2 . PHE A 1 360 ? 129.629 526.629 69.262 1.00 23.43 ? 414 PHE A CD2 1 ATOM 2434 C CE1 . PHE A 1 360 ? 126.931 527.119 69.389 1.00 24.87 ? 414 PHE A CE1 1 ATOM 2435 C CE2 . PHE A 1 360 ? 129.028 526.945 70.476 1.00 24.71 ? 414 PHE A CE2 1 ATOM 2436 C CZ . PHE A 1 360 ? 127.685 527.195 70.527 1.00 22.39 ? 414 PHE A CZ 1 ATOM 2437 N N . SER A 1 361 ? 128.463 529.349 66.703 1.00 21.95 ? 415 SER A N 1 ATOM 2438 C CA . SER A 1 361 ? 127.282 530.199 66.738 1.00 20.25 ? 415 SER A CA 1 ATOM 2439 C C . SER A 1 361 ? 127.208 531.154 65.564 1.00 22.96 ? 415 SER A C 1 ATOM 2440 O O . SER A 1 361 ? 126.147 531.726 65.304 1.00 21.39 ? 415 SER A O 1 ATOM 2441 C CB . SER A 1 361 ? 127.175 530.907 68.076 1.00 21.04 ? 415 SER A CB 1 ATOM 2442 O OG . SER A 1 361 ? 128.162 531.908 68.214 1.00 32.84 ? 415 SER A OG 1 ATOM 2443 N N . LEU A 1 362 ? 128.314 531.261 64.813 1.00 21.30 ? 416 LEU A N 1 ATOM 2444 C CA . LEU A 1 362 ? 128.409 532.065 63.590 1.00 21.07 ? 416 LEU A CA 1 ATOM 2445 C C . LEU A 1 362 ? 128.090 531.252 62.346 1.00 26.59 ? 416 LEU A C 1 ATOM 2446 O O . LEU A 1 362 ? 127.976 531.829 61.252 1.00 28.39 ? 416 LEU A O 1 ATOM 2447 C CB . LEU A 1 362 ? 129.771 532.751 63.488 1.00 21.01 ? 416 LEU A CB 1 ATOM 2448 C CG . LEU A 1 362 ? 130.037 533.761 64.579 1.00 24.84 ? 416 LEU A CG 1 ATOM 2449 C CD1 . LEU A 1 362 ? 131.390 534.338 64.433 1.00 24.49 ? 416 LEU A CD1 1 ATOM 2450 C CD2 . LEU A 1 362 ? 129.000 534.861 64.548 1.00 27.22 ? 416 LEU A CD2 1 ATOM 2451 N N . GLY A 1 363 ? 127.901 529.934 62.515 1.00 20.52 ? 417 GLY A N 1 ATOM 2452 C CA . GLY A 1 363 ? 127.438 529.075 61.445 1.00 19.11 ? 417 GLY A CA 1 ATOM 2453 C C . GLY A 1 363 ? 125.929 529.195 61.241 1.00 23.24 ? 417 GLY A C 1 ATOM 2454 O O . GLY A 1 363 ? 125.283 530.174 61.650 1.00 21.72 ? 417 GLY A O 1 ATOM 2455 N N . TYR A 1 364 ? 125.359 528.172 60.608 1.00 19.92 ? 418 TYR A N 1 ATOM 2456 C CA . TYR A 1 364 ? 123.940 528.130 60.299 1.00 20.47 ? 418 TYR A CA 1 ATOM 2457 C C . TYR A 1 364 ? 123.181 527.386 61.367 1.00 26.87 ? 418 TYR A C 1 ATOM 2458 O O . TYR A 1 364 ? 123.615 526.323 61.805 1.00 28.05 ? 418 TYR A O 1 ATOM 2459 C CB . TYR A 1 364 ? 123.703 527.552 58.898 1.00 20.12 ? 418 TYR A CB 1 ATOM 2460 C CG . TYR A 1 364 ? 122.251 527.287 58.603 1.00 20.79 ? 418 TYR A CG 1 ATOM 2461 C CD1 . TYR A 1 364 ? 121.331 528.332 58.535 1.00 23.37 ? 418 TYR A CD1 1 ATOM 2462 C CD2 . TYR A 1 364 ? 121.777 525.985 58.436 1.00 20.78 ? 418 TYR A CD2 1 ATOM 2463 C CE1 . TYR A 1 364 ? 119.970 528.086 58.360 1.00 23.52 ? 418 TYR A CE1 1 ATOM 2464 C CE2 . TYR A 1 364 ? 120.420 525.729 58.240 1.00 20.02 ? 418 TYR A CE2 1 ATOM 2465 C CZ . TYR A 1 364 ? 119.525 526.784 58.195 1.00 26.48 ? 418 TYR A CZ 1 ATOM 2466 O OH . TYR A 1 364 ? 118.191 526.561 57.959 1.00 32.81 ? 418 TYR A OH 1 ATOM 2467 N N . HIS A 1 365 ? 122.062 527.968 61.807 1.00 24.21 ? 419 HIS A N 1 ATOM 2468 C CA . HIS A 1 365 ? 121.202 527.399 62.853 1.00 22.67 ? 419 HIS A CA 1 ATOM 2469 C C . HIS A 1 365 ? 119.870 526.954 62.234 1.00 22.51 ? 419 HIS A C 1 ATOM 2470 O O . HIS A 1 365 ? 119.233 527.752 61.553 1.00 19.69 ? 419 HIS A O 1 ATOM 2471 C CB . HIS A 1 365 ? 120.898 528.459 63.911 1.00 22.32 ? 419 HIS A CB 1 ATOM 2472 C CG . HIS A 1 365 ? 122.082 528.970 64.648 1.00 25.49 ? 419 HIS A CG 1 ATOM 2473 N ND1 . HIS A 1 365 ? 122.391 528.515 65.920 1.00 27.48 ? 419 HIS A ND1 1 ATOM 2474 C CD2 . HIS A 1 365 ? 122.959 529.936 64.306 1.00 27.45 ? 419 HIS A CD2 1 ATOM 2475 C CE1 . HIS A 1 365 ? 123.469 529.183 66.289 1.00 26.86 ? 419 HIS A CE1 1 ATOM 2476 N NE2 . HIS A 1 365 ? 123.838 530.061 65.356 1.00 27.28 ? 419 HIS A NE2 1 ATOM 2477 N N . GLN A 1 366 ? 119.454 525.715 62.501 1.00 17.67 ? 420 GLN A N 1 ATOM 2478 C CA . GLN A 1 366 ? 118.188 525.193 62.021 1.00 19.30 ? 420 GLN A CA 1 ATOM 2479 C C . GLN A 1 366 ? 117.234 525.007 63.190 1.00 24.38 ? 420 GLN A C 1 ATOM 2480 O O . GLN A 1 366 ? 117.474 524.205 64.110 1.00 23.12 ? 420 GLN A O 1 ATOM 2481 C CB . GLN A 1 366 ? 118.361 523.865 61.268 1.00 20.99 ? 420 GLN A CB 1 ATOM 2482 C CG . GLN A 1 366 ? 117.027 523.292 60.783 1.00 26.73 ? 420 GLN A CG 1 ATOM 2483 C CD . GLN A 1 366 ? 116.438 524.120 59.678 1.00 31.03 ? 420 GLN A CD 1 ATOM 2484 O OE1 . GLN A 1 366 ? 117.035 524.277 58.615 1.00 22.48 ? 420 GLN A OE1 1 ATOM 2485 N NE2 . GLN A 1 366 ? 115.249 524.634 59.889 1.00 23.32 ? 420 GLN A NE2 1 ATOM 2486 N N . SER A 1 367 ? 116.110 525.708 63.091 1.00 22.70 ? 421 SER A N 1 ATOM 2487 C CA . SER A 1 367 ? 115.074 525.744 64.119 1.00 22.36 ? 421 SER A CA 1 ATOM 2488 C C . SER A 1 367 ? 113.679 525.693 63.526 1.00 23.90 ? 421 SER A C 1 ATOM 2489 O O . SER A 1 367 ? 113.467 525.977 62.344 1.00 22.43 ? 421 SER A O 1 ATOM 2490 C CB . SER A 1 367 ? 115.198 527.052 64.917 1.00 26.21 ? 421 SER A CB 1 ATOM 2491 O OG . SER A 1 367 ? 114.422 527.048 66.108 1.00 25.11 ? 421 SER A OG 1 ATOM 2492 N N . ARG A 1 368 ? 112.720 525.367 64.386 1.00 19.10 ? 422 ARG A N 1 ATOM 2493 C CA . ARG A 1 368 ? 111.300 525.529 64.171 1.00 18.52 ? 422 ARG A CA 1 ATOM 2494 C C . ARG A 1 368 ? 110.603 525.263 65.460 1.00 24.21 ? 422 ARG A C 1 ATOM 2495 O O . ARG A 1 368 ? 111.164 524.612 66.343 1.00 23.47 ? 422 ARG A O 1 ATOM 2496 C CB . ARG A 1 368 ? 110.705 524.666 63.029 1.00 16.47 ? 422 ARG A CB 1 ATOM 2497 C CG . ARG A 1 368 ? 110.556 523.194 63.321 1.00 17.70 ? 422 ARG A CG 1 ATOM 2498 C CD . ARG A 1 368 ? 109.791 522.537 62.199 1.00 22.64 ? 422 ARG A CD 1 ATOM 2499 N NE . ARG A 1 368 ? 108.355 522.820 62.223 1.00 30.04 ? 422 ARG A NE 1 ATOM 2500 C CZ . ARG A 1 368 ? 107.678 523.574 61.355 1.00 46.95 ? 422 ARG A CZ 1 ATOM 2501 N NH1 . ARG A 1 368 ? 108.310 524.195 60.357 1.00 41.10 ? 422 ARG A NH1 1 ATOM 2502 N NH2 . ARG A 1 368 ? 106.374 523.741 61.497 1.00 27.34 ? 422 ARG A NH2 1 ATOM 2503 N N . TRP A 1 369 ? 109.339 525.690 65.536 1.00 21.68 ? 423 TRP A N 1 ATOM 2504 C CA . TRP A 1 369 ? 108.468 525.336 66.635 1.00 21.64 ? 423 TRP A CA 1 ATOM 2505 C C . TRP A 1 369 ? 107.583 524.230 66.053 1.00 25.12 ? 423 TRP A C 1 ATOM 2506 O O . TRP A 1 369 ? 106.672 524.562 65.325 1.00 26.23 ? 423 TRP A O 1 ATOM 2507 C CB . TRP A 1 369 ? 107.660 526.567 67.028 1.00 20.87 ? 423 TRP A CB 1 ATOM 2508 C CG . TRP A 1 369 ? 106.694 526.396 68.168 1.00 22.02 ? 423 TRP A CG 1 ATOM 2509 C CD1 . TRP A 1 369 ? 106.589 525.342 69.036 1.00 24.74 ? 423 TRP A CD1 1 ATOM 2510 C CD2 . TRP A 1 369 ? 105.725 527.359 68.581 1.00 22.28 ? 423 TRP A CD2 1 ATOM 2511 N NE1 . TRP A 1 369 ? 105.595 525.584 69.951 1.00 25.11 ? 423 TRP A NE1 1 ATOM 2512 C CE2 . TRP A 1 369 ? 105.055 526.827 69.701 1.00 26.93 ? 423 TRP A CE2 1 ATOM 2513 C CE3 . TRP A 1 369 ? 105.381 528.645 68.135 1.00 23.50 ? 423 TRP A CE3 1 ATOM 2514 C CZ2 . TRP A 1 369 ? 104.031 527.524 70.348 1.00 25.64 ? 423 TRP A CZ2 1 ATOM 2515 C CZ3 . TRP A 1 369 ? 104.358 529.321 68.769 1.00 24.53 ? 423 TRP A CZ3 1 ATOM 2516 C CH2 . TRP A 1 369 ? 103.718 528.776 69.875 1.00 24.98 ? 423 TRP A CH2 1 ATOM 2517 N N . ASN A 1 370 ? 107.832 522.933 66.270 1.00 21.40 ? 424 ASN A N 1 ATOM 2518 C CA . ASN A 1 370 ? 108.894 522.345 67.044 1.00 22.13 ? 424 ASN A CA 1 ATOM 2519 C C . ASN A 1 370 ? 109.377 521.125 66.335 1.00 28.73 ? 424 ASN A C 1 ATOM 2520 O O . ASN A 1 370 ? 108.579 520.460 65.673 1.00 30.63 ? 424 ASN A O 1 ATOM 2521 C CB . ASN A 1 370 ? 108.320 521.872 68.370 1.00 19.58 ? 424 ASN A CB 1 ATOM 2522 C CG . ASN A 1 370 ? 109.222 522.091 69.550 1.00 31.75 ? 424 ASN A CG 1 ATOM 2523 O OD1 . ASN A 1 370 ? 109.018 523.045 70.262 1.00 27.01 ? 424 ASN A OD1 1 ATOM 2524 N ND2 . ASN A 1 370 ? 110.165 521.174 69.840 1.00 18.25 ? 424 ASN A ND2 1 ATOM 2525 N N . TYR A 1 371 ? 110.648 520.752 66.543 1.00 26.23 ? 425 TYR A N 1 ATOM 2526 C CA . TYR A 1 371 ? 111.082 519.435 66.140 1.00 27.40 ? 425 TYR A CA 1 ATOM 2527 C C . TYR A 1 371 ? 110.384 518.498 67.128 1.00 34.18 ? 425 TYR A C 1 ATOM 2528 O O . TYR A 1 371 ? 110.251 518.828 68.316 1.00 34.47 ? 425 TYR A O 1 ATOM 2529 C CB . TYR A 1 371 ? 112.605 519.318 66.063 1.00 29.18 ? 425 TYR A CB 1 ATOM 2530 C CG . TYR A 1 371 ? 113.080 520.105 64.866 1.00 30.80 ? 425 TYR A CG 1 ATOM 2531 C CD1 . TYR A 1 371 ? 112.539 519.877 63.601 1.00 32.96 ? 425 TYR A CD1 1 ATOM 2532 C CD2 . TYR A 1 371 ? 113.961 521.177 65.015 1.00 31.34 ? 425 TYR A CD2 1 ATOM 2533 C CE1 . TYR A 1 371 ? 112.895 520.660 62.508 1.00 34.54 ? 425 TYR A CE1 1 ATOM 2534 C CE2 . TYR A 1 371 ? 114.346 521.954 63.920 1.00 31.51 ? 425 TYR A CE2 1 ATOM 2535 C CZ . TYR A 1 371 ? 113.798 521.698 62.672 1.00 37.20 ? 425 TYR A CZ 1 ATOM 2536 O OH . TYR A 1 371 ? 114.091 522.481 61.594 1.00 33.54 ? 425 TYR A OH 1 ATOM 2537 N N . ARG A 1 372 ? 109.772 517.432 66.605 1.00 30.66 ? 426 ARG A N 1 ATOM 2538 C CA . ARG A 1 372 ? 108.841 516.610 67.360 1.00 29.86 ? 426 ARG A CA 1 ATOM 2539 C C . ARG A 1 372 ? 109.419 515.780 68.485 1.00 34.95 ? 426 ARG A C 1 ATOM 2540 O O . ARG A 1 372 ? 108.791 515.664 69.530 1.00 34.80 ? 426 ARG A O 1 ATOM 2541 C CB . ARG A 1 372 ? 108.066 515.700 66.398 1.00 27.03 ? 426 ARG A CB 1 ATOM 2542 C CG . ARG A 1 372 ? 107.142 516.450 65.405 1.00 24.98 ? 426 ARG A CG 1 ATOM 2543 C CD . ARG A 1 372 ? 106.519 515.530 64.346 1.00 24.24 ? 426 ARG A CD 1 ATOM 2544 N NE . ARG A 1 372 ? 107.529 514.643 63.740 1.00 45.55 ? 426 ARG A NE 1 ATOM 2545 C CZ . ARG A 1 372 ? 108.109 514.808 62.549 1.00 50.15 ? 426 ARG A CZ 1 ATOM 2546 N NH1 . ARG A 1 372 ? 107.745 515.811 61.752 1.00 29.29 ? 426 ARG A NH1 1 ATOM 2547 N NH2 . ARG A 1 372 ? 109.051 513.967 62.145 1.00 26.83 ? 426 ARG A NH2 1 ATOM 2548 N N . ASP A 1 373 ? 110.587 515.200 68.269 1.00 32.51 ? 427 ASP A N 1 ATOM 2549 C CA . ASP A 1 373 ? 111.184 514.184 69.120 1.00 33.58 ? 427 ASP A CA 1 ATOM 2550 C C . ASP A 1 373 ? 112.623 513.908 68.678 1.00 40.44 ? 427 ASP A C 1 ATOM 2551 O O . ASP A 1 373 ? 113.085 514.501 67.693 1.00 40.59 ? 427 ASP A O 1 ATOM 2552 C CB . ASP A 1 373 ? 110.356 512.872 68.975 1.00 35.57 ? 427 ASP A CB 1 ATOM 2553 C CG . ASP A 1 373 ? 109.983 512.499 67.532 1.00 46.19 ? 427 ASP A CG 1 ATOM 2554 O OD1 . ASP A 1 373 ? 110.849 512.619 66.643 1.00 44.70 ? 427 ASP A OD1 1 ATOM 2555 O OD2 . ASP A 1 373 ? 108.794 512.153 67.284 1.00 53.74 ? 427 ASP A OD2 1 ATOM 2556 N N . GLU A 1 374 ? 113.316 512.972 69.375 1.00 37.11 ? 428 GLU A N 1 ATOM 2557 C CA . GLU A 1 374 ? 114.697 512.617 69.061 1.00 36.77 ? 428 GLU A CA 1 ATOM 2558 C C . GLU A 1 374 ? 114.846 512.140 67.634 1.00 40.20 ? 428 GLU A C 1 ATOM 2559 O O . GLU A 1 374 ? 115.813 512.526 66.994 1.00 40.72 ? 428 GLU A O 1 ATOM 2560 C CB . GLU A 1 374 ? 115.264 511.571 69.994 1.00 37.92 ? 428 GLU A CB 1 ATOM 2561 C CG . GLU A 1 374 ? 115.167 511.918 71.458 1.00 45.14 ? 428 GLU A CG 1 ATOM 2562 C CD . GLU A 1 374 ? 115.722 510.862 72.398 1.00 62.13 ? 428 GLU A CD 1 ATOM 2563 O OE1 . GLU A 1 374 ? 115.905 511.220 73.577 1.00 41.03 ? 428 GLU A OE1 1 ATOM 2564 O OE2 . GLU A 1 374 ? 116.008 509.714 71.976 1.00 56.33 ? 428 GLU A OE2 1 ATOM 2565 N N . ALA A 1 375 ? 113.886 511.353 67.120 1.00 34.91 ? 429 ALA A N 1 ATOM 2566 C CA . ALA A 1 375 ? 113.911 510.867 65.742 1.00 34.06 ? 429 ALA A CA 1 ATOM 2567 C C . ALA A 1 375 ? 113.891 512.007 64.744 1.00 37.27 ? 429 ALA A C 1 ATOM 2568 O O . ALA A 1 375 ? 114.636 511.963 63.777 1.00 36.77 ? 429 ALA A O 1 ATOM 2569 C CB . ALA A 1 375 ? 112.739 509.942 65.478 1.00 34.62 ? 429 ALA A CB 1 ATOM 2570 N N . ASP A 1 376 ? 113.032 513.009 64.960 1.00 33.58 ? 430 ASP A N 1 ATOM 2571 C CA . ASP A 1 376 ? 112.932 514.180 64.112 1.00 31.55 ? 430 ASP A CA 1 ATOM 2572 C C . ASP A 1 376 ? 114.269 514.948 64.099 1.00 34.53 ? 430 ASP A C 1 ATOM 2573 O O . ASP A 1 376 ? 114.806 515.226 63.027 1.00 33.95 ? 430 ASP A O 1 ATOM 2574 C CB . ASP A 1 376 ? 111.777 515.057 64.564 1.00 31.82 ? 430 ASP A CB 1 ATOM 2575 C CG . ASP A 1 376 ? 111.391 516.125 63.574 1.00 40.06 ? 430 ASP A CG 1 ATOM 2576 O OD1 . ASP A 1 376 ? 111.928 516.120 62.435 1.00 44.58 ? 430 ASP A OD1 1 ATOM 2577 O OD2 . ASP A 1 376 ? 110.549 516.952 63.914 1.00 39.37 ? 430 ASP A OD2 1 ATOM 2578 N N . VAL A 1 377 ? 114.846 515.200 65.278 1.00 30.98 ? 431 VAL A N 1 ATOM 2579 C CA . VAL A 1 377 ? 116.151 515.869 65.401 1.00 29.74 ? 431 VAL A CA 1 ATOM 2580 C C . VAL A 1 377 ? 117.232 515.112 64.638 1.00 33.92 ? 431 VAL A C 1 ATOM 2581 O O . VAL A 1 377 ? 117.996 515.737 63.911 1.00 34.63 ? 431 VAL A O 1 ATOM 2582 C CB . VAL A 1 377 ? 116.538 516.088 66.881 1.00 31.54 ? 431 VAL A CB 1 ATOM 2583 C CG1 . VAL A 1 377 ? 117.983 516.547 67.024 1.00 30.49 ? 431 VAL A CG1 1 ATOM 2584 C CG2 . VAL A 1 377 ? 115.605 517.098 67.516 1.00 31.09 ? 431 VAL A CG2 1 ATOM 2585 N N . LEU A 1 378 ? 117.284 513.770 64.792 1.00 29.10 ? 432 LEU A N 1 ATOM 2586 C CA . LEU A 1 378 ? 118.269 512.945 64.118 1.00 27.69 ? 432 LEU A CA 1 ATOM 2587 C C . LEU A 1 378 ? 118.029 512.835 62.597 1.00 31.70 ? 432 LEU A C 1 ATOM 2588 O O . LEU A 1 378 ? 119.019 512.799 61.852 1.00 30.97 ? 432 LEU A O 1 ATOM 2589 C CB . LEU A 1 378 ? 118.448 511.591 64.784 1.00 27.78 ? 432 LEU A CB 1 ATOM 2590 C CG . LEU A 1 378 ? 118.899 511.591 66.277 1.00 33.25 ? 432 LEU A CG 1 ATOM 2591 C CD1 . LEU A 1 378 ? 119.305 510.211 66.715 1.00 34.17 ? 432 LEU A CD1 1 ATOM 2592 C CD2 . LEU A 1 378 ? 120.035 512.571 66.581 1.00 35.64 ? 432 LEU A CD2 1 ATOM 2593 N N . GLU A 1 379 ? 116.760 512.888 62.130 1.00 28.34 ? 433 GLU A N 1 ATOM 2594 C CA . GLU A 1 379 ? 116.443 512.903 60.702 1.00 28.40 ? 433 GLU A CA 1 ATOM 2595 C C . GLU A 1 379 ? 116.831 514.254 60.107 1.00 31.63 ? 433 GLU A C 1 ATOM 2596 O O . GLU A 1 379 ? 117.294 514.312 58.962 1.00 31.26 ? 433 GLU A O 1 ATOM 2597 C CB . GLU A 1 379 ? 114.945 512.678 60.471 1.00 30.54 ? 433 GLU A CB 1 ATOM 2598 C CG . GLU A 1 379 ? 114.482 511.244 60.669 1.00 45.14 ? 433 GLU A CG 1 ATOM 2599 C CD . GLU A 1 379 ? 112.978 511.046 60.811 1.00 77.90 ? 433 GLU A CD 1 ATOM 2600 O OE1 . GLU A 1 379 ? 112.576 510.017 61.405 1.00 67.15 ? 433 GLU A OE1 1 ATOM 2601 O OE2 . GLU A 1 379 ? 112.203 511.915 60.343 1.00 74.38 ? 433 GLU A OE2 1 ATOM 2602 N N . VAL A 1 380 ? 116.645 515.351 60.877 1.00 26.42 ? 434 VAL A N 1 ATOM 2603 C CA . VAL A 1 380 ? 117.011 516.692 60.400 1.00 24.89 ? 434 VAL A CA 1 ATOM 2604 C C . VAL A 1 380 ? 118.530 516.764 60.282 1.00 29.29 ? 434 VAL A C 1 ATOM 2605 O O . VAL A 1 380 ? 119.053 517.159 59.239 1.00 29.40 ? 434 VAL A O 1 ATOM 2606 C CB . VAL A 1 380 ? 116.434 517.785 61.287 1.00 26.67 ? 434 VAL A CB 1 ATOM 2607 C CG1 . VAL A 1 380 ? 117.087 519.130 60.998 1.00 25.58 ? 434 VAL A CG1 1 ATOM 2608 C CG2 . VAL A 1 380 ? 114.916 517.859 61.128 1.00 25.78 ? 434 VAL A CG2 1 ATOM 2609 N N . ASP A 1 381 ? 119.229 516.295 61.309 1.00 23.66 ? 435 ASP A N 1 ATOM 2610 C CA . ASP A 1 381 ? 120.675 516.207 61.260 1.00 23.81 ? 435 ASP A CA 1 ATOM 2611 C C . ASP A 1 381 ? 121.179 515.415 60.033 1.00 28.45 ? 435 ASP A C 1 ATOM 2612 O O . ASP A 1 381 ? 122.107 515.850 59.355 1.00 25.93 ? 435 ASP A O 1 ATOM 2613 C CB . ASP A 1 381 ? 121.166 515.558 62.544 1.00 25.53 ? 435 ASP A CB 1 ATOM 2614 C CG . ASP A 1 381 ? 122.620 515.196 62.479 1.00 33.71 ? 435 ASP A CG 1 ATOM 2615 O OD1 . ASP A 1 381 ? 123.457 516.087 62.718 1.00 34.27 ? 435 ASP A OD1 1 ATOM 2616 O OD2 . ASP A 1 381 ? 122.923 514.024 62.173 1.00 41.15 ? 435 ASP A OD2 1 ATOM 2617 N N . GLN A 1 382 ? 120.578 514.238 59.784 1.00 28.48 ? 436 GLN A N 1 ATOM 2618 C CA . GLN A 1 382 ? 120.952 513.357 58.692 1.00 29.30 ? 436 GLN A CA 1 ATOM 2619 C C . GLN A 1 382 ? 120.575 513.950 57.350 1.00 35.17 ? 436 GLN A C 1 ATOM 2620 O O . GLN A 1 382 ? 121.329 513.791 56.390 1.00 37.22 ? 436 GLN A O 1 ATOM 2621 C CB . GLN A 1 382 ? 120.379 511.945 58.902 1.00 30.52 ? 436 GLN A CB 1 ATOM 2622 C CG . GLN A 1 382 ? 120.985 510.883 57.996 1.00 33.27 ? 436 GLN A CG 1 ATOM 2623 C CD . GLN A 1 382 ? 122.489 510.797 58.105 1.00 35.40 ? 436 GLN A CD 1 ATOM 2624 O OE1 . GLN A 1 382 ? 123.064 510.774 59.200 1.00 24.65 ? 436 GLN A OE1 1 ATOM 2625 N NE2 . GLN A 1 382 ? 123.148 510.824 56.961 1.00 21.08 ? 436 GLN A NE2 1 ATOM 2626 N N . GLY A 1 383 ? 119.467 514.694 57.313 1.00 31.67 ? 437 GLY A N 1 ATOM 2627 C CA . GLY A 1 383 ? 118.993 515.442 56.143 1.00 30.69 ? 437 GLY A CA 1 ATOM 2628 C C . GLY A 1 383 ? 120.016 516.442 55.616 1.00 32.95 ? 437 GLY A C 1 ATOM 2629 O O . GLY A 1 383 ? 120.289 516.478 54.405 1.00 33.79 ? 437 GLY A O 1 ATOM 2630 N N . PHE A 1 384 ? 120.662 517.197 56.528 1.00 26.56 ? 438 PHE A N 1 ATOM 2631 C CA . PHE A 1 384 ? 121.741 518.105 56.130 1.00 25.48 ? 438 PHE A CA 1 ATOM 2632 C C . PHE A 1 384 ? 122.861 517.382 55.443 1.00 25.89 ? 438 PHE A C 1 ATOM 2633 O O . PHE A 1 384 ? 123.283 517.813 54.382 1.00 24.45 ? 438 PHE A O 1 ATOM 2634 C CB . PHE A 1 384 ? 122.291 518.908 57.320 1.00 26.51 ? 438 PHE A CB 1 ATOM 2635 C CG . PHE A 1 384 ? 121.369 520.030 57.669 1.00 27.68 ? 438 PHE A CG 1 ATOM 2636 C CD1 . PHE A 1 384 ? 121.302 521.159 56.873 1.00 29.73 ? 438 PHE A CD1 1 ATOM 2637 C CD2 . PHE A 1 384 ? 120.517 519.935 58.768 1.00 29.80 ? 438 PHE A CD2 1 ATOM 2638 C CE1 . PHE A 1 384 ? 120.398 522.167 57.156 1.00 30.51 ? 438 PHE A CE1 1 ATOM 2639 C CE2 . PHE A 1 384 ? 119.626 520.960 59.067 1.00 31.45 ? 438 PHE A CE2 1 ATOM 2640 C CZ . PHE A 1 384 ? 119.573 522.067 58.260 1.00 29.56 ? 438 PHE A CZ 1 ATOM 2641 N N . ASP A 1 385 ? 123.305 516.258 56.021 1.00 21.45 ? 439 ASP A N 1 ATOM 2642 C CA . ASP A 1 385 ? 124.414 515.487 55.481 1.00 19.19 ? 439 ASP A CA 1 ATOM 2643 C C . ASP A 1 385 ? 124.067 514.784 54.205 1.00 23.25 ? 439 ASP A C 1 ATOM 2644 O O . ASP A 1 385 ? 124.885 514.778 53.298 1.00 22.37 ? 439 ASP A O 1 ATOM 2645 C CB . ASP A 1 385 ? 124.957 514.551 56.537 1.00 19.78 ? 439 ASP A CB 1 ATOM 2646 C CG . ASP A 1 385 ? 125.586 515.318 57.667 1.00 25.18 ? 439 ASP A CG 1 ATOM 2647 O OD1 . ASP A 1 385 ? 125.927 516.501 57.465 1.00 29.18 ? 439 ASP A OD1 1 ATOM 2648 O OD2 . ASP A 1 385 ? 125.728 514.752 58.749 1.00 31.67 ? 439 ASP A OD2 1 ATOM 2649 N N . ASP A 1 386 ? 122.828 514.277 54.082 1.00 22.94 ? 440 ASP A N 1 ATOM 2650 C CA . ASP A 1 386 ? 122.422 513.615 52.856 1.00 23.59 ? 440 ASP A CA 1 ATOM 2651 C C . ASP A 1 386 ? 122.256 514.580 51.713 1.00 27.37 ? 440 ASP A C 1 ATOM 2652 O O . ASP A 1 386 ? 122.384 514.189 50.550 1.00 27.18 ? 440 ASP A O 1 ATOM 2653 C CB . ASP A 1 386 ? 121.162 512.771 53.073 1.00 25.81 ? 440 ASP A CB 1 ATOM 2654 C CG . ASP A 1 386 ? 121.310 511.563 54.001 1.00 35.90 ? 440 ASP A CG 1 ATOM 2655 O OD1 . ASP A 1 386 ? 122.472 511.131 54.262 1.00 33.42 ? 440 ASP A OD1 1 ATOM 2656 O OD2 . ASP A 1 386 ? 120.269 511.020 54.425 1.00 44.31 ? 440 ASP A OD2 1 ATOM 2657 N N . HIS A 1 387 ? 122.013 515.847 52.025 1.00 25.63 ? 441 HIS A N 1 ATOM 2658 C CA . HIS A 1 387 ? 121.818 516.837 50.973 1.00 26.69 ? 441 HIS A CA 1 ATOM 2659 C C . HIS A 1 387 ? 122.987 517.813 50.819 1.00 30.36 ? 441 HIS A C 1 ATOM 2660 O O . HIS A 1 387 ? 122.894 518.754 50.026 1.00 30.51 ? 441 HIS A O 1 ATOM 2661 C CB . HIS A 1 387 ? 120.476 517.538 51.168 1.00 28.47 ? 441 HIS A CB 1 ATOM 2662 C CG . HIS A 1 387 ? 119.331 516.584 50.965 1.00 32.69 ? 441 HIS A CG 1 ATOM 2663 N ND1 . HIS A 1 387 ? 118.798 515.847 52.022 1.00 35.19 ? 441 HIS A ND1 1 ATOM 2664 C CD2 . HIS A 1 387 ? 118.704 516.217 49.827 1.00 34.52 ? 441 HIS A CD2 1 ATOM 2665 C CE1 . HIS A 1 387 ? 117.856 515.082 51.493 1.00 34.37 ? 441 HIS A CE1 1 ATOM 2666 N NE2 . HIS A 1 387 ? 117.759 515.276 50.179 1.00 34.49 ? 441 HIS A NE2 1 ATOM 2667 N N . ASN A 1 388 ? 124.121 517.518 51.484 1.00 26.06 ? 442 ASN A N 1 ATOM 2668 C CA . ASN A 1 388 ? 125.336 518.304 51.404 1.00 25.23 ? 442 ASN A CA 1 ATOM 2669 C C . ASN A 1 388 ? 125.047 519.777 51.684 1.00 27.86 ? 442 ASN A C 1 ATOM 2670 O O . ASN A 1 388 ? 125.331 520.646 50.864 1.00 25.52 ? 442 ASN A O 1 ATOM 2671 C CB . ASN A 1 388 ? 126.024 518.115 50.038 1.00 24.74 ? 442 ASN A CB 1 ATOM 2672 C CG . ASN A 1 388 ? 127.401 518.740 49.975 1.00 41.46 ? 442 ASN A CG 1 ATOM 2673 O OD1 . ASN A 1 388 ? 128.086 518.908 51.010 1.00 27.49 ? 442 ASN A OD1 1 ATOM 2674 N ND2 . ASN A 1 388 ? 127.812 519.143 48.765 1.00 30.23 ? 442 ASN A ND2 1 ATOM 2675 N N . MET A 1 389 ? 124.429 520.040 52.828 1.00 26.04 ? 443 MET A N 1 ATOM 2676 C CA . MET A 1 389 ? 124.158 521.395 53.288 1.00 25.28 ? 443 MET A CA 1 ATOM 2677 C C . MET A 1 389 ? 124.728 521.516 54.683 1.00 27.95 ? 443 MET A C 1 ATOM 2678 O O . MET A 1 389 ? 124.412 520.670 55.526 1.00 26.42 ? 443 MET A O 1 ATOM 2679 C CB . MET A 1 389 ? 122.670 521.674 53.310 1.00 27.68 ? 443 MET A CB 1 ATOM 2680 C CG . MET A 1 389 ? 122.110 521.858 51.938 1.00 31.31 ? 443 MET A CG 1 ATOM 2681 S SD . MET A 1 389 ? 120.318 521.892 52.006 1.00 35.12 ? 443 MET A SD 1 ATOM 2682 C CE . MET A 1 389 ? 119.976 521.827 50.314 1.00 31.93 ? 443 MET A CE 1 ATOM 2683 N N . PRO A 1 390 ? 125.624 522.509 54.943 1.00 24.10 ? 444 PRO A N 1 ATOM 2684 C CA . PRO A 1 390 ? 126.175 522.650 56.292 1.00 22.77 ? 444 PRO A CA 1 ATOM 2685 C C . PRO A 1 390 ? 125.176 523.216 57.309 1.00 24.04 ? 444 PRO A C 1 ATOM 2686 O O . PRO A 1 390 ? 124.261 523.960 56.973 1.00 24.11 ? 444 PRO A O 1 ATOM 2687 C CB . PRO A 1 390 ? 127.372 523.577 56.081 1.00 24.06 ? 444 PRO A CB 1 ATOM 2688 C CG . PRO A 1 390 ? 126.948 524.432 55.008 1.00 28.40 ? 444 PRO A CG 1 ATOM 2689 C CD . PRO A 1 390 ? 126.184 523.545 54.054 1.00 25.02 ? 444 PRO A CD 1 ATOM 2690 N N . CYS A 1 391 ? 125.374 522.838 58.555 1.00 17.74 ? 445 CYS A N 1 ATOM 2691 C CA . CYS A 1 391 ? 124.573 523.268 59.679 1.00 17.11 ? 445 CYS A CA 1 ATOM 2692 C C . CYS A 1 391 ? 125.349 523.074 60.976 1.00 21.35 ? 445 CYS A C 1 ATOM 2693 O O . CYS A 1 391 ? 125.862 521.976 61.203 1.00 22.27 ? 445 CYS A O 1 ATOM 2694 C CB . CYS A 1 391 ? 123.283 522.480 59.737 1.00 16.69 ? 445 CYS A CB 1 ATOM 2695 S SG . CYS A 1 391 ? 122.259 522.940 61.142 1.00 19.33 ? 445 CYS A SG 1 ATOM 2696 N N . ASP A 1 392 ? 125.378 524.071 61.858 1.00 16.13 ? 446 ASP A N 1 ATOM 2697 C CA . ASP A 1 392 ? 126.078 523.859 63.125 1.00 16.75 ? 446 ASP A CA 1 ATOM 2698 C C . ASP A 1 392 ? 125.175 523.464 64.270 1.00 21.81 ? 446 ASP A C 1 ATOM 2699 O O . ASP A 1 392 ? 125.629 522.765 65.171 1.00 21.64 ? 446 ASP A O 1 ATOM 2700 C CB . ASP A 1 392 ? 126.861 525.116 63.554 1.00 18.53 ? 446 ASP A CB 1 ATOM 2701 C CG . ASP A 1 392 ? 128.281 525.082 63.093 1.00 25.43 ? 446 ASP A CG 1 ATOM 2702 O OD1 . ASP A 1 392 ? 128.506 525.150 61.875 1.00 25.43 ? 446 ASP A OD1 1 ATOM 2703 O OD2 . ASP A 1 392 ? 129.161 524.888 63.934 1.00 36.24 ? 446 ASP A OD2 1 ATOM 2704 N N . VAL A 1 393 ? 123.943 523.998 64.305 1.00 19.74 ? 447 VAL A N 1 ATOM 2705 C CA . VAL A 1 393 ? 123.062 523.840 65.456 1.00 20.14 ? 447 VAL A CA 1 ATOM 2706 C C . VAL A 1 393 ? 121.657 523.498 65.065 1.00 26.47 ? 447 VAL A C 1 ATOM 2707 O O . VAL A 1 393 ? 121.133 524.053 64.091 1.00 25.83 ? 447 VAL A O 1 ATOM 2708 C CB . VAL A 1 393 ? 123.056 525.140 66.322 1.00 23.07 ? 447 VAL A CB 1 ATOM 2709 C CG1 . VAL A 1 393 ? 122.470 524.876 67.686 1.00 21.60 ? 447 VAL A CG1 1 ATOM 2710 C CG2 . VAL A 1 393 ? 124.454 525.750 66.467 1.00 23.39 ? 447 VAL A CG2 1 ATOM 2711 N N . ILE A 1 394 ? 121.022 522.610 65.865 1.00 24.14 ? 448 ILE A N 1 ATOM 2712 C CA . ILE A 1 394 ? 119.609 522.248 65.719 1.00 22.97 ? 448 ILE A CA 1 ATOM 2713 C C . ILE A 1 394 ? 118.951 522.701 66.978 1.00 26.56 ? 448 ILE A C 1 ATOM 2714 O O . ILE A 1 394 ? 119.496 522.501 68.058 1.00 25.81 ? 448 ILE A O 1 ATOM 2715 C CB . ILE A 1 394 ? 119.389 520.758 65.369 1.00 25.01 ? 448 ILE A CB 1 ATOM 2716 C CG1 . ILE A 1 394 ? 119.997 520.469 63.982 1.00 24.47 ? 448 ILE A CG1 1 ATOM 2717 C CG2 . ILE A 1 394 ? 117.888 520.402 65.362 1.00 24.39 ? 448 ILE A CG2 1 ATOM 2718 C CD1 . ILE A 1 394 ? 120.087 519.019 63.618 1.00 30.63 ? 448 ILE A CD1 1 ATOM 2719 N N . TRP A 1 395 ? 117.807 523.362 66.840 1.00 24.47 ? 449 TRP A N 1 ATOM 2720 C CA . TRP A 1 395 ? 117.137 524.001 67.960 1.00 24.46 ? 449 TRP A CA 1 ATOM 2721 C C . TRP A 1 395 ? 115.919 523.267 68.434 1.00 31.36 ? 449 TRP A C 1 ATOM 2722 O O . TRP A 1 395 ? 115.164 522.706 67.629 1.00 31.25 ? 449 TRP A O 1 ATOM 2723 C CB . TRP A 1 395 ? 116.787 525.448 67.583 1.00 22.71 ? 449 TRP A CB 1 ATOM 2724 C CG . TRP A 1 395 ? 117.962 526.367 67.454 1.00 23.18 ? 449 TRP A CG 1 ATOM 2725 C CD1 . TRP A 1 395 ? 119.122 526.132 66.782 1.00 25.81 ? 449 TRP A CD1 1 ATOM 2726 C CD2 . TRP A 1 395 ? 118.105 527.649 68.059 1.00 23.29 ? 449 TRP A CD2 1 ATOM 2727 N NE1 . TRP A 1 395 ? 119.989 527.175 66.953 1.00 25.17 ? 449 TRP A NE1 1 ATOM 2728 C CE2 . TRP A 1 395 ? 119.394 528.126 67.734 1.00 26.64 ? 449 TRP A CE2 1 ATOM 2729 C CE3 . TRP A 1 395 ? 117.280 528.437 68.869 1.00 24.75 ? 449 TRP A CE3 1 ATOM 2730 C CZ2 . TRP A 1 395 ? 119.868 529.369 68.168 1.00 25.48 ? 449 TRP A CZ2 1 ATOM 2731 C CZ3 . TRP A 1 395 ? 117.757 529.662 69.308 1.00 26.51 ? 449 TRP A CZ3 1 ATOM 2732 C CH2 . TRP A 1 395 ? 119.049 530.101 68.978 1.00 26.93 ? 449 TRP A CH2 1 ATOM 2733 N N . LEU A 1 396 ? 115.718 523.305 69.772 1.00 29.61 ? 450 LEU A N 1 ATOM 2734 C CA . LEU A 1 396 ? 114.587 522.714 70.486 1.00 28.35 ? 450 LEU A CA 1 ATOM 2735 C C . LEU A 1 396 ? 113.749 523.779 71.125 1.00 32.75 ? 450 LEU A C 1 ATOM 2736 O O . LEU A 1 396 ? 114.161 524.363 72.124 1.00 33.95 ? 450 LEU A O 1 ATOM 2737 C CB . LEU A 1 396 ? 115.071 521.698 71.530 1.00 27.74 ? 450 LEU A CB 1 ATOM 2738 C CG . LEU A 1 396 ? 115.660 520.435 70.908 1.00 33.95 ? 450 LEU A CG 1 ATOM 2739 C CD1 . LEU A 1 396 ? 115.888 519.360 71.939 1.00 35.33 ? 450 LEU A CD1 1 ATOM 2740 C CD2 . LEU A 1 396 ? 114.769 519.907 69.767 1.00 34.58 ? 450 LEU A CD2 1 ATOM 2741 N N . ASP A 1 397 ? 112.558 524.021 70.562 1.00 28.05 ? 451 ASP A N 1 ATOM 2742 C CA . ASP A 1 397 ? 111.592 524.974 71.092 1.00 27.22 ? 451 ASP A CA 1 ATOM 2743 C C . ASP A 1 397 ? 110.802 524.342 72.262 1.00 31.40 ? 451 ASP A C 1 ATOM 2744 O O . ASP A 1 397 ? 111.144 523.253 72.727 1.00 30.79 ? 451 ASP A O 1 ATOM 2745 C CB . ASP A 1 397 ? 110.704 525.530 69.973 1.00 28.20 ? 451 ASP A CB 1 ATOM 2746 C CG . ASP A 1 397 ? 110.224 526.941 70.155 1.00 28.22 ? 451 ASP A CG 1 ATOM 2747 O OD1 . ASP A 1 397 ? 109.979 527.352 71.322 1.00 29.35 ? 451 ASP A OD1 1 ATOM 2748 O OD2 . ASP A 1 397 ? 110.027 527.621 69.142 1.00 25.64 ? 451 ASP A OD2 1 ATOM 2749 N N . ILE A 1 398 ? 109.778 525.045 72.753 1.00 27.37 ? 452 ILE A N 1 ATOM 2750 C CA . ILE A 1 398 ? 109.054 524.773 73.992 1.00 25.50 ? 452 ILE A CA 1 ATOM 2751 C C . ILE A 1 398 ? 108.461 523.371 74.110 1.00 28.60 ? 452 ILE A C 1 ATOM 2752 O O . ILE A 1 398 ? 108.328 522.878 75.236 1.00 29.08 ? 452 ILE A O 1 ATOM 2753 C CB . ILE A 1 398 ? 108.013 525.849 74.309 1.00 26.61 ? 452 ILE A CB 1 ATOM 2754 C CG1 . ILE A 1 398 ? 106.942 525.997 73.217 1.00 25.76 ? 452 ILE A CG1 1 ATOM 2755 C CG2 . ILE A 1 398 ? 108.721 527.168 74.606 1.00 26.52 ? 452 ILE A CG2 1 ATOM 2756 C CD1 . ILE A 1 398 ? 105.898 527.018 73.557 1.00 24.80 ? 452 ILE A CD1 1 ATOM 2757 N N . GLU A 1 399 ? 108.164 522.715 72.992 1.00 22.59 ? 453 GLU A N 1 ATOM 2758 C CA . GLU A 1 399 ? 107.622 521.362 73.047 1.00 22.22 ? 453 GLU A CA 1 ATOM 2759 C C . GLU A 1 399 ? 108.634 520.327 73.519 1.00 27.92 ? 453 GLU A C 1 ATOM 2760 O O . GLU A 1 399 ? 108.243 519.221 73.824 1.00 28.91 ? 453 GLU A O 1 ATOM 2761 C CB . GLU A 1 399 ? 106.963 520.935 71.718 1.00 23.02 ? 453 GLU A CB 1 ATOM 2762 C CG . GLU A 1 399 ? 105.982 521.942 71.130 1.00 27.30 ? 453 GLU A CG 1 ATOM 2763 C CD . GLU A 1 399 ? 104.942 522.513 72.069 1.00 44.05 ? 453 GLU A CD 1 ATOM 2764 O OE1 . GLU A 1 399 ? 104.444 521.750 72.926 1.00 25.33 ? 453 GLU A OE1 1 ATOM 2765 O OE2 . GLU A 1 399 ? 104.598 523.709 71.926 1.00 43.90 ? 453 GLU A OE2 1 ATOM 2766 N N . HIS A 1 400 ? 109.918 520.667 73.644 1.00 24.30 ? 454 HIS A N 1 ATOM 2767 C CA . HIS A 1 400 ? 110.850 519.658 74.117 1.00 23.18 ? 454 HIS A CA 1 ATOM 2768 C C . HIS A 1 400 ? 110.773 519.384 75.612 1.00 29.24 ? 454 HIS A C 1 ATOM 2769 O O . HIS A 1 400 ? 111.288 518.360 76.056 1.00 28.85 ? 454 HIS A O 1 ATOM 2770 C CB . HIS A 1 400 ? 112.280 520.033 73.747 1.00 23.07 ? 454 HIS A CB 1 ATOM 2771 C CG . HIS A 1 400 ? 112.959 520.951 74.719 1.00 26.00 ? 454 HIS A CG 1 ATOM 2772 N ND1 . HIS A 1 400 ? 112.822 522.313 74.617 1.00 27.65 ? 454 HIS A ND1 1 ATOM 2773 C CD2 . HIS A 1 400 ? 113.799 520.669 75.744 1.00 27.51 ? 454 HIS A CD2 1 ATOM 2774 C CE1 . HIS A 1 400 ? 113.554 522.825 75.587 1.00 27.47 ? 454 HIS A CE1 1 ATOM 2775 N NE2 . HIS A 1 400 ? 114.168 521.870 76.288 1.00 27.77 ? 454 HIS A NE2 1 ATOM 2776 N N . ALA A 1 401 ? 110.271 520.353 76.397 1.00 26.25 ? 455 ALA A N 1 ATOM 2777 C CA . ALA A 1 401 ? 110.250 520.267 77.861 1.00 24.93 ? 455 ALA A CA 1 ATOM 2778 C C . ALA A 1 401 ? 109.041 519.490 78.331 1.00 27.85 ? 455 ALA A C 1 ATOM 2779 O O . ALA A 1 401 ? 108.170 519.180 77.515 1.00 29.18 ? 455 ALA A O 1 ATOM 2780 C CB . ALA A 1 401 ? 110.228 521.679 78.437 1.00 25.38 ? 455 ALA A CB 1 ATOM 2781 N N . ASP A 1 402 ? 108.971 519.165 79.622 1.00 23.48 ? 456 ASP A N 1 ATOM 2782 C CA . ASP A 1 402 ? 107.785 518.504 80.131 1.00 23.90 ? 456 ASP A CA 1 ATOM 2783 C C . ASP A 1 402 ? 106.736 519.588 80.449 1.00 30.64 ? 456 ASP A C 1 ATOM 2784 O O . ASP A 1 402 ? 106.809 520.231 81.496 1.00 29.83 ? 456 ASP A O 1 ATOM 2785 C CB . ASP A 1 402 ? 108.100 517.636 81.348 1.00 24.78 ? 456 ASP A CB 1 ATOM 2786 C CG . ASP A 1 402 ? 106.883 517.222 82.139 1.00 24.58 ? 456 ASP A CG 1 ATOM 2787 O OD1 . ASP A 1 402 ? 105.789 517.124 81.545 1.00 27.21 ? 456 ASP A OD1 1 ATOM 2788 O OD2 . ASP A 1 402 ? 107.009 517.047 83.354 1.00 26.24 ? 456 ASP A OD2 1 ATOM 2789 N N . GLY A 1 403 ? 105.795 519.778 79.529 1.00 27.49 ? 457 GLY A N 1 ATOM 2790 C CA . GLY A 1 403 ? 104.723 520.744 79.687 1.00 27.94 ? 457 GLY A CA 1 ATOM 2791 C C . GLY A 1 403 ? 105.132 522.150 80.053 1.00 32.25 ? 457 GLY A C 1 ATOM 2792 O O . GLY A 1 403 ? 104.521 522.767 80.932 1.00 32.94 ? 457 GLY A O 1 ATOM 2793 N N . LYS A 1 404 ? 106.150 522.664 79.366 1.00 28.87 ? 458 LYS A N 1 ATOM 2794 C CA . LYS A 1 404 ? 106.659 524.029 79.506 1.00 27.98 ? 458 LYS A CA 1 ATOM 2795 C C . LYS A 1 404 ? 107.216 524.313 80.902 1.00 28.10 ? 458 LYS A C 1 ATOM 2796 O O . LYS A 1 404 ? 107.213 525.454 81.361 1.00 25.69 ? 458 LYS A O 1 ATOM 2797 C CB . LYS A 1 404 ? 105.624 525.079 79.062 1.00 31.01 ? 458 LYS A CB 1 ATOM 2798 C CG . LYS A 1 404 ? 105.424 525.145 77.547 1.00 37.72 ? 458 LYS A CG 1 ATOM 2799 C CD . LYS A 1 404 ? 104.442 524.109 77.079 1.00 36.51 ? 458 LYS A CD 1 ATOM 2800 C CE . LYS A 1 404 ? 104.237 524.117 75.609 1.00 38.84 ? 458 LYS A CE 1 ATOM 2801 N NZ . LYS A 1 404 ? 103.623 522.841 75.226 1.00 42.25 ? 458 LYS A NZ 1 ATOM 2802 N N . ARG A 1 405 ? 107.716 523.250 81.552 1.00 23.57 ? 459 ARG A N 1 ATOM 2803 C CA . ARG A 1 405 ? 108.508 523.307 82.784 1.00 22.40 ? 459 ARG A CA 1 ATOM 2804 C C . ARG A 1 405 ? 109.954 523.349 82.270 1.00 25.88 ? 459 ARG A C 1 ATOM 2805 O O . ARG A 1 405 ? 110.502 522.345 81.811 1.00 24.78 ? 459 ARG A O 1 ATOM 2806 C CB . ARG A 1 405 ? 108.302 522.079 83.674 1.00 18.40 ? 459 ARG A CB 1 ATOM 2807 C CG . ARG A 1 405 ? 106.890 521.982 84.227 1.00 24.39 ? 459 ARG A CG 1 ATOM 2808 C CD . ARG A 1 405 ? 106.604 520.593 84.828 1.00 26.44 ? 459 ARG A CD 1 ATOM 2809 N NE . ARG A 1 405 ? 105.222 520.454 85.317 1.00 23.21 ? 459 ARG A NE 1 ATOM 2810 C CZ . ARG A 1 405 ? 104.142 520.286 84.552 1.00 27.94 ? 459 ARG A CZ 1 ATOM 2811 N NH1 . ARG A 1 405 ? 102.939 520.194 85.103 1.00 17.39 ? 459 ARG A NH1 1 ATOM 2812 N NH2 . ARG A 1 405 ? 104.252 520.253 83.224 1.00 10.22 ? 459 ARG A NH2 1 ATOM 2813 N N . TYR A 1 406 ? 110.578 524.517 82.345 1.00 22.78 ? 460 TYR A N 1 ATOM 2814 C CA . TYR A 1 406 ? 111.950 524.666 81.828 1.00 21.08 ? 460 TYR A CA 1 ATOM 2815 C C . TYR A 1 406 ? 112.940 523.896 82.662 1.00 23.46 ? 460 TYR A C 1 ATOM 2816 O O . TYR A 1 406 ? 112.676 523.571 83.819 1.00 25.91 ? 460 TYR A O 1 ATOM 2817 C CB . TYR A 1 406 ? 112.330 526.140 81.583 1.00 19.96 ? 460 TYR A CB 1 ATOM 2818 C CG . TYR A 1 406 ? 111.279 526.722 80.678 1.00 21.28 ? 460 TYR A CG 1 ATOM 2819 C CD1 . TYR A 1 406 ? 111.071 526.203 79.404 1.00 22.28 ? 460 TYR A CD1 1 ATOM 2820 C CD2 . TYR A 1 406 ? 110.350 527.640 81.163 1.00 22.42 ? 460 TYR A CD2 1 ATOM 2821 C CE1 . TYR A 1 406 ? 110.010 526.636 78.610 1.00 24.49 ? 460 TYR A CE1 1 ATOM 2822 C CE2 . TYR A 1 406 ? 109.269 528.059 80.390 1.00 22.75 ? 460 TYR A CE2 1 ATOM 2823 C CZ . TYR A 1 406 ? 109.101 527.556 79.112 1.00 30.46 ? 460 TYR A CZ 1 ATOM 2824 O OH . TYR A 1 406 ? 108.050 528.014 78.335 1.00 28.02 ? 460 TYR A OH 1 ATOM 2825 N N . PHE A 1 407 ? 114.033 523.505 82.015 1.00 16.71 ? 461 PHE A N 1 ATOM 2826 C CA . PHE A 1 407 ? 115.070 522.634 82.540 1.00 15.15 ? 461 PHE A CA 1 ATOM 2827 C C . PHE A 1 407 ? 114.615 521.173 82.612 1.00 20.37 ? 461 PHE A C 1 ATOM 2828 O O . PHE A 1 407 ? 115.275 520.384 83.271 1.00 19.62 ? 461 PHE A O 1 ATOM 2829 C CB . PHE A 1 407 ? 115.647 523.099 83.894 1.00 16.14 ? 461 PHE A CB 1 ATOM 2830 C CG . PHE A 1 407 ? 116.157 524.518 83.960 1.00 16.72 ? 461 PHE A CG 1 ATOM 2831 C CD1 . PHE A 1 407 ? 117.464 524.824 83.583 1.00 18.51 ? 461 PHE A CD1 1 ATOM 2832 C CD2 . PHE A 1 407 ? 115.359 525.540 84.464 1.00 17.73 ? 461 PHE A CD2 1 ATOM 2833 C CE1 . PHE A 1 407 ? 117.952 526.139 83.669 1.00 18.22 ? 461 PHE A CE1 1 ATOM 2834 C CE2 . PHE A 1 407 ? 115.843 526.858 84.528 1.00 21.18 ? 461 PHE A CE2 1 ATOM 2835 C CZ . PHE A 1 407 ? 117.147 527.144 84.135 1.00 18.37 ? 461 PHE A CZ 1 ATOM 2836 N N . THR A 1 408 ? 113.523 520.798 81.927 1.00 19.76 ? 462 THR A N 1 ATOM 2837 C CA . THR A 1 408 ? 113.046 519.406 81.905 1.00 20.29 ? 462 THR A CA 1 ATOM 2838 C C . THR A 1 408 ? 112.912 518.953 80.483 1.00 26.36 ? 462 THR A C 1 ATOM 2839 O O . THR A 1 408 ? 113.038 519.744 79.561 1.00 23.57 ? 462 THR A O 1 ATOM 2840 C CB . THR A 1 408 ? 111.703 519.208 82.647 1.00 29.97 ? 462 THR A CB 1 ATOM 2841 O OG1 . THR A 1 408 ? 110.643 519.767 81.881 1.00 32.70 ? 462 THR A OG1 1 ATOM 2842 C CG2 . THR A 1 408 ? 111.706 519.757 84.084 1.00 23.89 ? 462 THR A CG2 1 ATOM 2843 N N . TRP A 1 409 ? 112.635 517.676 80.314 1.00 28.51 ? 463 TRP A N 1 ATOM 2844 C CA . TRP A 1 409 ? 112.480 517.057 79.021 1.00 30.25 ? 463 TRP A CA 1 ATOM 2845 C C . TRP A 1 409 ? 111.191 516.277 78.989 1.00 34.92 ? 463 TRP A C 1 ATOM 2846 O O . TRP A 1 409 ? 110.846 515.617 79.976 1.00 35.78 ? 463 TRP A O 1 ATOM 2847 C CB . TRP A 1 409 ? 113.655 516.097 78.801 1.00 29.98 ? 463 TRP A CB 1 ATOM 2848 C CG . TRP A 1 409 ? 115.007 516.757 78.826 1.00 31.07 ? 463 TRP A CG 1 ATOM 2849 C CD1 . TRP A 1 409 ? 115.840 516.908 79.900 1.00 33.91 ? 463 TRP A CD1 1 ATOM 2850 C CD2 . TRP A 1 409 ? 115.690 517.320 77.706 1.00 30.97 ? 463 TRP A CD2 1 ATOM 2851 N NE1 . TRP A 1 409 ? 116.997 517.550 79.516 1.00 33.10 ? 463 TRP A NE1 1 ATOM 2852 C CE2 . TRP A 1 409 ? 116.929 517.815 78.171 1.00 34.56 ? 463 TRP A CE2 1 ATOM 2853 C CE3 . TRP A 1 409 ? 115.376 517.449 76.341 1.00 32.12 ? 463 TRP A CE3 1 ATOM 2854 C CZ2 . TRP A 1 409 ? 117.858 518.417 77.314 1.00 33.63 ? 463 TRP A CZ2 1 ATOM 2855 C CZ3 . TRP A 1 409 ? 116.304 518.033 75.494 1.00 33.41 ? 463 TRP A CZ3 1 ATOM 2856 C CH2 . TRP A 1 409 ? 117.516 518.531 75.984 1.00 33.90 ? 463 TRP A CH2 1 ATOM 2857 N N . ASP A 1 410 ? 110.464 516.357 77.869 1.00 31.15 ? 464 ASP A N 1 ATOM 2858 C CA . ASP A 1 410 ? 109.269 515.536 77.689 1.00 31.29 ? 464 ASP A CA 1 ATOM 2859 C C . ASP A 1 410 ? 109.776 514.066 77.538 1.00 38.80 ? 464 ASP A C 1 ATOM 2860 O O . ASP A 1 410 ? 110.519 513.773 76.595 1.00 38.41 ? 464 ASP A O 1 ATOM 2861 C CB . ASP A 1 410 ? 108.453 515.996 76.478 1.00 32.25 ? 464 ASP A CB 1 ATOM 2862 C CG . ASP A 1 410 ? 107.245 515.107 76.177 1.00 41.45 ? 464 ASP A CG 1 ATOM 2863 O OD1 . ASP A 1 410 ? 107.383 513.888 76.197 1.00 40.68 ? 464 ASP A OD1 1 ATOM 2864 O OD2 . ASP A 1 410 ? 106.169 515.635 75.940 1.00 49.70 ? 464 ASP A OD2 1 ATOM 2865 N N . PRO A 1 411 ? 109.394 513.142 78.459 1.00 37.62 ? 465 PRO A N 1 ATOM 2866 C CA . PRO A 1 411 ? 109.901 511.746 78.388 1.00 37.44 ? 465 PRO A CA 1 ATOM 2867 C C . PRO A 1 411 ? 109.413 510.893 77.216 1.00 39.67 ? 465 PRO A C 1 ATOM 2868 O O . PRO A 1 411 ? 110.052 509.891 76.916 1.00 38.90 ? 465 PRO A O 1 ATOM 2869 C CB . PRO A 1 411 ? 109.476 511.146 79.732 1.00 39.29 ? 465 PRO A CB 1 ATOM 2870 C CG . PRO A 1 411 ? 108.261 511.926 80.108 1.00 43.74 ? 465 PRO A CG 1 ATOM 2871 C CD . PRO A 1 411 ? 108.483 513.320 79.607 1.00 39.22 ? 465 PRO A CD 1 ATOM 2872 N N . THR A 1 412 ? 108.321 511.299 76.538 1.00 36.09 ? 466 THR A N 1 ATOM 2873 C CA . THR A 1 412 ? 107.806 510.632 75.340 1.00 35.55 ? 466 THR A CA 1 ATOM 2874 C C . THR A 1 412 ? 108.670 511.015 74.117 1.00 39.28 ? 466 THR A C 1 ATOM 2875 O O . THR A 1 412 ? 109.118 510.150 73.369 1.00 40.02 ? 466 THR A O 1 ATOM 2876 C CB . THR A 1 412 ? 106.331 511.029 75.099 1.00 42.34 ? 466 THR A CB 1 ATOM 2877 O OG1 . THR A 1 412 ? 105.548 510.572 76.191 1.00 44.44 ? 466 THR A OG1 1 ATOM 2878 C CG2 . THR A 1 412 ? 105.762 510.449 73.805 1.00 42.34 ? 466 THR A CG2 1 ATOM 2879 N N . ARG A 1 413 ? 108.877 512.318 73.934 1.00 34.16 ? 467 ARG A N 1 ATOM 2880 C CA . ARG A 1 413 ? 109.554 512.931 72.813 1.00 32.70 ? 467 ARG A CA 1 ATOM 2881 C C . ARG A 1 413 ? 111.062 512.853 72.930 1.00 36.76 ? 467 ARG A C 1 ATOM 2882 O O . ARG A 1 413 ? 111.747 512.594 71.937 1.00 34.50 ? 467 ARG A O 1 ATOM 2883 C CB . ARG A 1 413 ? 109.122 514.398 72.690 1.00 28.87 ? 467 ARG A CB 1 ATOM 2884 C CG . ARG A 1 413 ? 107.669 514.662 72.299 1.00 29.44 ? 467 ARG A CG 1 ATOM 2885 C CD . ARG A 1 413 ? 107.452 516.180 72.302 1.00 36.90 ? 467 ARG A CD 1 ATOM 2886 N NE . ARG A 1 413 ? 106.038 516.571 72.312 1.00 36.18 ? 467 ARG A NE 1 ATOM 2887 C CZ . ARG A 1 413 ? 105.433 517.296 73.263 1.00 76.78 ? 467 ARG A CZ 1 ATOM 2888 N NH1 . ARG A 1 413 ? 106.122 517.756 74.309 1.00 68.72 ? 467 ARG A NH1 1 ATOM 2889 N NH2 . ARG A 1 413 ? 104.141 517.578 73.168 1.00 80.43 ? 467 ARG A NH2 1 ATOM 2890 N N . PHE A 1 414 ? 111.585 513.109 74.137 1.00 34.76 ? 468 PHE A N 1 ATOM 2891 C CA . PHE A 1 414 ? 113.028 513.100 74.394 1.00 35.03 ? 468 PHE A CA 1 ATOM 2892 C C . PHE A 1 414 ? 113.376 512.262 75.622 1.00 41.68 ? 468 PHE A C 1 ATOM 2893 O O . PHE A 1 414 ? 113.807 512.827 76.626 1.00 40.91 ? 468 PHE A O 1 ATOM 2894 C CB . PHE A 1 414 ? 113.594 514.546 74.502 1.00 35.66 ? 468 PHE A CB 1 ATOM 2895 C CG . PHE A 1 414 ? 113.285 515.402 73.296 1.00 35.48 ? 468 PHE A CG 1 ATOM 2896 C CD1 . PHE A 1 414 ? 114.108 515.379 72.184 1.00 36.40 ? 468 PHE A CD1 1 ATOM 2897 C CD2 . PHE A 1 414 ? 112.126 516.166 73.242 1.00 36.52 ? 468 PHE A CD2 1 ATOM 2898 C CE1 . PHE A 1 414 ? 113.797 516.129 71.053 1.00 36.53 ? 468 PHE A CE1 1 ATOM 2899 C CE2 . PHE A 1 414 ? 111.800 516.890 72.090 1.00 38.74 ? 468 PHE A CE2 1 ATOM 2900 C CZ . PHE A 1 414 ? 112.645 516.873 71.009 1.00 36.13 ? 468 PHE A CZ 1 ATOM 2901 N N . PRO A 1 415 ? 113.220 510.909 75.572 1.00 39.94 ? 469 PRO A N 1 ATOM 2902 C CA . PRO A 1 415 ? 113.556 510.095 76.762 1.00 39.74 ? 469 PRO A CA 1 ATOM 2903 C C . PRO A 1 415 ? 115.045 510.036 77.105 1.00 42.36 ? 469 PRO A C 1 ATOM 2904 O O . PRO A 1 415 ? 115.383 509.739 78.250 1.00 41.00 ? 469 PRO A O 1 ATOM 2905 C CB . PRO A 1 415 ? 113.087 508.686 76.376 1.00 41.53 ? 469 PRO A CB 1 ATOM 2906 C CG . PRO A 1 415 ? 113.052 508.694 74.875 1.00 45.45 ? 469 PRO A CG 1 ATOM 2907 C CD . PRO A 1 415 ? 112.652 510.070 74.490 1.00 40.80 ? 469 PRO A CD 1 ATOM 2908 N N . GLN A 1 416 ? 115.934 510.222 76.113 1.00 39.16 ? 470 GLN A N 1 ATOM 2909 C CA . GLN A 1 416 ? 117.387 510.068 76.308 1.00 39.50 ? 470 GLN A CA 1 ATOM 2910 C C . GLN A 1 416 ? 118.168 511.273 75.778 1.00 42.20 ? 470 GLN A C 1 ATOM 2911 O O . GLN A 1 416 ? 118.906 511.126 74.792 1.00 42.62 ? 470 GLN A O 1 ATOM 2912 C CB . GLN A 1 416 ? 117.859 508.793 75.598 1.00 41.45 ? 470 GLN A CB 1 ATOM 2913 C CG . GLN A 1 416 ? 117.269 507.490 76.146 1.00 64.14 ? 470 GLN A CG 1 ATOM 2914 C CD . GLN A 1 416 ? 117.765 507.147 77.543 1.00 87.88 ? 470 GLN A CD 1 ATOM 2915 O OE1 . GLN A 1 416 ? 118.824 507.613 78.004 1.00 82.45 ? 470 GLN A OE1 1 ATOM 2916 N NE2 . GLN A 1 416 ? 116.994 506.333 78.257 1.00 82.08 ? 470 GLN A NE2 1 ATOM 2917 N N . PRO A 1 417 ? 117.985 512.475 76.399 1.00 36.65 ? 471 PRO A N 1 ATOM 2918 C CA . PRO A 1 417 ? 118.659 513.682 75.896 1.00 35.55 ? 471 PRO A CA 1 ATOM 2919 C C . PRO A 1 417 ? 120.180 513.565 75.754 1.00 39.32 ? 471 PRO A C 1 ATOM 2920 O O . PRO A 1 417 ? 120.703 514.007 74.730 1.00 38.24 ? 471 PRO A O 1 ATOM 2921 C CB . PRO A 1 417 ? 118.233 514.768 76.890 1.00 36.86 ? 471 PRO A CB 1 ATOM 2922 C CG . PRO A 1 417 ? 117.785 514.037 78.109 1.00 40.87 ? 471 PRO A CG 1 ATOM 2923 C CD . PRO A 1 417 ? 117.161 512.794 77.585 1.00 37.32 ? 471 PRO A CD 1 ATOM 2924 N N . LEU A 1 418 ? 120.879 512.926 76.717 1.00 36.18 ? 472 LEU A N 1 ATOM 2925 C CA . LEU A 1 418 ? 122.327 512.775 76.621 1.00 35.99 ? 472 LEU A CA 1 ATOM 2926 C C . LEU A 1 418 ? 122.733 511.972 75.408 1.00 39.03 ? 472 LEU A C 1 ATOM 2927 O O . LEU A 1 418 ? 123.752 512.288 74.805 1.00 38.29 ? 472 LEU A O 1 ATOM 2928 C CB . LEU A 1 418 ? 122.940 512.158 77.875 1.00 36.50 ? 472 LEU A CB 1 ATOM 2929 C CG . LEU A 1 418 ? 122.912 512.986 79.147 1.00 41.47 ? 472 LEU A CG 1 ATOM 2930 C CD1 . LEU A 1 418 ? 123.662 512.272 80.237 1.00 41.33 ? 472 LEU A CD1 1 ATOM 2931 C CD2 . LEU A 1 418 ? 123.563 514.341 78.952 1.00 45.90 ? 472 LEU A CD2 1 ATOM 2932 N N . ASN A 1 419 ? 121.922 510.971 75.023 1.00 35.02 ? 473 ASN A N 1 ATOM 2933 C CA . ASN A 1 419 ? 122.227 510.148 73.855 1.00 35.18 ? 473 ASN A CA 1 ATOM 2934 C C . ASN A 1 419 ? 122.018 510.906 72.561 1.00 37.69 ? 473 ASN A C 1 ATOM 2935 O O . ASN A 1 419 ? 122.813 510.769 71.623 1.00 36.36 ? 473 ASN A O 1 ATOM 2936 C CB . ASN A 1 419 ? 121.475 508.813 73.885 1.00 40.25 ? 473 ASN A CB 1 ATOM 2937 C CG . ASN A 1 419 ? 122.007 507.827 74.924 1.00 63.89 ? 473 ASN A CG 1 ATOM 2938 O OD1 . ASN A 1 419 ? 123.080 508.006 75.525 1.00 52.05 ? 473 ASN A OD1 1 ATOM 2939 N ND2 . ASN A 1 419 ? 121.272 506.744 75.152 1.00 58.45 ? 473 ASN A ND2 1 ATOM 2940 N N . MET A 1 420 ? 120.985 511.744 72.526 1.00 34.44 ? 474 MET A N 1 ATOM 2941 C CA . MET A 1 420 ? 120.717 512.628 71.396 1.00 34.31 ? 474 MET A CA 1 ATOM 2942 C C . MET A 1 420 ? 121.899 513.608 71.218 1.00 38.81 ? 474 MET A C 1 ATOM 2943 O O . MET A 1 420 ? 122.409 513.769 70.117 1.00 39.28 ? 474 MET A O 1 ATOM 2944 C CB . MET A 1 420 ? 119.392 513.373 71.628 1.00 36.20 ? 474 MET A CB 1 ATOM 2945 C CG . MET A 1 420 ? 119.104 514.436 70.596 1.00 39.81 ? 474 MET A CG 1 ATOM 2946 S SD . MET A 1 420 ? 117.572 515.321 70.870 1.00 43.84 ? 474 MET A SD 1 ATOM 2947 C CE . MET A 1 420 ? 117.831 515.998 72.462 1.00 40.26 ? 474 MET A CE 1 ATOM 2948 N N . LEU A 1 421 ? 122.341 514.221 72.313 1.00 36.28 ? 475 LEU A N 1 ATOM 2949 C CA . LEU A 1 421 ? 123.478 515.140 72.351 1.00 36.99 ? 475 LEU A CA 1 ATOM 2950 C C . LEU A 1 421 ? 124.784 514.478 71.951 1.00 38.59 ? 475 LEU A C 1 ATOM 2951 O O . LEU A 1 421 ? 125.584 515.082 71.219 1.00 38.56 ? 475 LEU A O 1 ATOM 2952 C CB . LEU A 1 421 ? 123.581 515.786 73.732 1.00 37.79 ? 475 LEU A CB 1 ATOM 2953 C CG . LEU A 1 421 ? 122.490 516.827 73.999 1.00 41.74 ? 475 LEU A CG 1 ATOM 2954 C CD1 . LEU A 1 421 ? 122.374 517.113 75.471 1.00 41.52 ? 475 LEU A CD1 1 ATOM 2955 C CD2 . LEU A 1 421 ? 122.744 518.103 73.209 1.00 42.10 ? 475 LEU A CD2 1 ATOM 2956 N N . GLU A 1 422 ? 124.969 513.222 72.376 1.00 32.86 ? 476 GLU A N 1 ATOM 2957 C CA . GLU A 1 422 ? 126.122 512.433 71.971 1.00 32.41 ? 476 GLU A CA 1 ATOM 2958 C C . GLU A 1 422 ? 126.112 512.211 70.460 1.00 32.93 ? 476 GLU A C 1 ATOM 2959 O O . GLU A 1 422 ? 127.167 512.374 69.850 1.00 33.29 ? 476 GLU A O 1 ATOM 2960 C CB . GLU A 1 422 ? 126.188 511.113 72.727 1.00 34.24 ? 476 GLU A CB 1 ATOM 2961 C CG . GLU A 1 422 ? 127.514 510.401 72.548 1.00 47.17 ? 476 GLU A CG 1 ATOM 2962 C CD . GLU A 1 422 ? 127.636 509.103 73.310 1.00 70.37 ? 476 GLU A CD 1 ATOM 2963 O OE1 . GLU A 1 422 ? 126.884 508.916 74.294 1.00 52.28 ? 476 GLU A OE1 1 ATOM 2964 O OE2 . GLU A 1 422 ? 128.508 508.284 72.940 1.00 76.52 ? 476 GLU A OE2 1 ATOM 2965 N N . HIS A 1 423 ? 124.940 511.857 69.861 1.00 27.39 ? 477 HIS A N 1 ATOM 2966 C CA A HIS A 1 423 ? 124.785 511.662 68.406 0.50 25.78 ? 477 HIS A CA 1 ATOM 2967 C CA B HIS A 1 423 ? 124.795 511.656 68.413 0.50 26.71 ? 477 HIS A CA 1 ATOM 2968 C C . HIS A 1 423 ? 125.152 512.953 67.683 1.00 30.58 ? 477 HIS A C 1 ATOM 2969 O O . HIS A 1 423 ? 125.929 512.917 66.728 1.00 31.12 ? 477 HIS A O 1 ATOM 2970 C CB A HIS A 1 423 ? 123.342 511.256 68.047 0.50 25.65 ? 477 HIS A CB 1 ATOM 2971 C CB B HIS A 1 423 ? 123.366 511.189 68.047 0.50 27.45 ? 477 HIS A CB 1 ATOM 2972 C CG A HIS A 1 423 ? 123.169 510.800 66.628 0.50 28.39 ? 477 HIS A CG 1 ATOM 2973 C CG B HIS A 1 423 ? 123.104 509.721 68.261 0.50 30.99 ? 477 HIS A CG 1 ATOM 2974 N ND1 A HIS A 1 423 ? 123.058 509.461 66.311 0.50 29.76 ? 477 HIS A ND1 1 ATOM 2975 N ND1 B HIS A 1 423 ? 121.943 509.278 68.881 0.50 32.68 ? 477 HIS A ND1 1 ATOM 2976 C CD2 A HIS A 1 423 ? 123.088 511.524 65.488 0.50 29.22 ? 477 HIS A CD2 1 ATOM 2977 C CD2 B HIS A 1 423 ? 123.843 508.641 67.901 0.50 32.77 ? 477 HIS A CD2 1 ATOM 2978 C CE1 A HIS A 1 423 ? 122.913 509.416 64.998 0.50 28.56 ? 477 HIS A CE1 1 ATOM 2979 C CE1 B HIS A 1 423 ? 122.019 507.958 68.886 0.50 32.13 ? 477 HIS A CE1 1 ATOM 2980 N NE2 A HIS A 1 423 ? 122.920 510.631 64.462 0.50 28.65 ? 477 HIS A NE2 1 ATOM 2981 N NE2 B HIS A 1 423 ? 123.145 507.529 68.309 0.50 32.59 ? 477 HIS A NE2 1 ATOM 2982 N N . LEU A 1 424 ? 124.611 514.111 68.149 1.00 27.63 ? 478 LEU A N 1 ATOM 2983 C CA . LEU A 1 424 ? 124.948 515.387 67.527 1.00 27.38 ? 478 LEU A CA 1 ATOM 2984 C C . LEU A 1 424 ? 126.456 515.702 67.701 1.00 29.91 ? 478 LEU A C 1 ATOM 2985 O O . LEU A 1 424 ? 127.086 516.187 66.757 1.00 27.77 ? 478 LEU A O 1 ATOM 2986 C CB . LEU A 1 424 ? 124.080 516.520 68.048 1.00 28.31 ? 478 LEU A CB 1 ATOM 2987 C CG . LEU A 1 424 ? 122.639 516.500 67.595 1.00 35.42 ? 478 LEU A CG 1 ATOM 2988 C CD1 . LEU A 1 424 ? 121.858 517.521 68.346 1.00 37.65 ? 478 LEU A CD1 1 ATOM 2989 C CD2 . LEU A 1 424 ? 122.528 516.875 66.148 1.00 42.04 ? 478 LEU A CD2 1 ATOM 2990 N N . ALA A 1 425 ? 127.049 515.384 68.880 1.00 25.15 ? 479 ALA A N 1 ATOM 2991 C CA . ALA A 1 425 ? 128.482 515.603 69.082 1.00 24.03 ? 479 ALA A CA 1 ATOM 2992 C C . ALA A 1 425 ? 129.323 514.747 68.132 1.00 31.08 ? 479 ALA A C 1 ATOM 2993 O O . ALA A 1 425 ? 130.400 515.192 67.705 1.00 31.49 ? 479 ALA A O 1 ATOM 2994 C CB . ALA A 1 425 ? 128.878 515.327 70.518 1.00 23.81 ? 479 ALA A CB 1 ATOM 2995 N N . SER A 1 426 ? 128.833 513.537 67.780 1.00 26.86 ? 480 SER A N 1 ATOM 2996 C CA . SER A 1 426 ? 129.558 512.690 66.851 1.00 26.66 ? 480 SER A CA 1 ATOM 2997 C C . SER A 1 426 ? 129.542 513.303 65.404 1.00 30.69 ? 480 SER A C 1 ATOM 2998 O O . SER A 1 426 ? 130.419 513.003 64.603 1.00 30.42 ? 480 SER A O 1 ATOM 2999 C CB . SER A 1 426 ? 129.026 511.258 66.893 1.00 30.08 ? 480 SER A CB 1 ATOM 3000 O OG . SER A 1 426 ? 127.852 511.130 66.102 1.00 41.10 ? 480 SER A OG 1 ATOM 3001 N N . LYS A 1 427 ? 128.539 514.142 65.085 1.00 26.83 ? 481 LYS A N 1 ATOM 3002 C CA . LYS A 1 427 ? 128.438 514.871 63.811 1.00 25.30 ? 481 LYS A CA 1 ATOM 3003 C C . LYS A 1 427 ? 129.116 516.258 63.941 1.00 26.66 ? 481 LYS A C 1 ATOM 3004 O O . LYS A 1 427 ? 129.106 517.042 62.986 1.00 24.59 ? 481 LYS A O 1 ATOM 3005 C CB . LYS A 1 427 ? 126.970 515.084 63.388 1.00 26.80 ? 481 LYS A CB 1 ATOM 3006 C CG . LYS A 1 427 ? 126.216 513.827 62.998 1.00 38.94 ? 481 LYS A CG 1 ATOM 3007 C CD . LYS A 1 427 ? 126.799 513.175 61.736 1.00 48.42 ? 481 LYS A CD 1 ATOM 3008 C CE . LYS A 1 427 ? 125.882 512.179 61.086 1.00 41.43 ? 481 LYS A CE 1 ATOM 3009 N NZ . LYS A 1 427 ? 124.712 512.836 60.443 1.00 27.36 ? 481 LYS A NZ 1 ATOM 3010 N N . ARG A 1 428 ? 129.687 516.547 65.128 1.00 22.22 ? 482 ARG A N 1 ATOM 3011 C CA . ARG A 1 428 ? 130.356 517.793 65.468 1.00 22.23 ? 482 ARG A CA 1 ATOM 3012 C C . ARG A 1 428 ? 129.390 518.991 65.366 1.00 27.20 ? 482 ARG A C 1 ATOM 3013 O O . ARG A 1 428 ? 129.717 520.028 64.795 1.00 27.01 ? 482 ARG A O 1 ATOM 3014 C CB . ARG A 1 428 ? 131.637 517.950 64.645 1.00 21.87 ? 482 ARG A CB 1 ATOM 3015 C CG . ARG A 1 428 ? 132.536 516.732 64.764 1.00 21.26 ? 482 ARG A CG 1 ATOM 3016 C CD . ARG A 1 428 ? 133.912 516.965 64.181 1.00 28.84 ? 482 ARG A CD 1 ATOM 3017 N NE . ARG A 1 428 ? 134.732 517.834 65.037 1.00 27.23 ? 482 ARG A NE 1 ATOM 3018 C CZ . ARG A 1 428 ? 135.972 518.222 64.761 1.00 31.33 ? 482 ARG A CZ 1 ATOM 3019 N NH1 . ARG A 1 428 ? 136.562 517.838 63.634 1.00 24.31 ? 482 ARG A NH1 1 ATOM 3020 N NH2 . ARG A 1 428 ? 136.629 519.000 65.604 1.00 17.08 ? 482 ARG A NH2 1 ATOM 3021 N N . ARG A 1 429 ? 128.180 518.803 65.912 1.00 24.08 ? 483 ARG A N 1 ATOM 3022 C CA . ARG A 1 429 ? 127.097 519.767 65.922 1.00 23.06 ? 483 ARG A CA 1 ATOM 3023 C C . ARG A 1 429 ? 126.660 520.005 67.344 1.00 28.49 ? 483 ARG A C 1 ATOM 3024 O O . ARG A 1 429 ? 127.052 519.269 68.263 1.00 30.53 ? 483 ARG A O 1 ATOM 3025 C CB . ARG A 1 429 ? 125.920 519.291 65.056 1.00 19.76 ? 483 ARG A CB 1 ATOM 3026 C CG . ARG A 1 429 ? 126.225 519.343 63.573 1.00 17.61 ? 483 ARG A CG 1 ATOM 3027 C CD . ARG A 1 429 ? 125.027 518.988 62.738 1.00 21.91 ? 483 ARG A CD 1 ATOM 3028 N NE . ARG A 1 429 ? 125.328 519.271 61.341 1.00 16.13 ? 483 ARG A NE 1 ATOM 3029 C CZ . ARG A 1 429 ? 125.422 518.374 60.370 1.00 30.66 ? 483 ARG A CZ 1 ATOM 3030 N NH1 . ARG A 1 429 ? 125.199 517.083 60.617 1.00 24.18 ? 483 ARG A NH1 1 ATOM 3031 N NH2 . ARG A 1 429 ? 125.722 518.757 59.138 1.00 23.15 ? 483 ARG A NH2 1 ATOM 3032 N N . LYS A 1 430 ? 125.900 521.075 67.524 1.00 22.39 ? 484 LYS A N 1 ATOM 3033 C CA . LYS A 1 430 ? 125.404 521.475 68.806 1.00 20.95 ? 484 LYS A CA 1 ATOM 3034 C C . LYS A 1 430 ? 123.899 521.484 68.764 1.00 22.03 ? 484 LYS A C 1 ATOM 3035 O O . LYS A 1 430 ? 123.275 521.379 67.701 1.00 18.65 ? 484 LYS A O 1 ATOM 3036 C CB . LYS A 1 430 ? 125.884 522.903 69.160 1.00 24.16 ? 484 LYS A CB 1 ATOM 3037 C CG . LYS A 1 430 ? 127.316 523.286 68.779 1.00 28.10 ? 484 LYS A CG 1 ATOM 3038 C CD . LYS A 1 430 ? 128.381 522.397 69.351 1.00 26.61 ? 484 LYS A CD 1 ATOM 3039 C CE . LYS A 1 430 ? 129.726 522.792 68.815 1.00 21.95 ? 484 LYS A CE 1 ATOM 3040 N NZ . LYS A 1 430 ? 130.728 521.845 69.344 1.00 23.73 ? 484 LYS A NZ 1 ATOM 3041 N N . LEU A 1 431 ? 123.324 521.645 69.952 1.00 19.41 ? 485 LEU A N 1 ATOM 3042 C CA . LEU A 1 431 ? 121.911 521.816 70.112 1.00 20.69 ? 485 LEU A CA 1 ATOM 3043 C C . LEU A 1 431 ? 121.664 523.092 70.950 1.00 21.02 ? 485 LEU A C 1 ATOM 3044 O O . LEU A 1 431 ? 122.501 523.500 71.762 1.00 20.06 ? 485 LEU A O 1 ATOM 3045 C CB . LEU A 1 431 ? 121.344 520.567 70.814 1.00 22.33 ? 485 LEU A CB 1 ATOM 3046 C CG . LEU A 1 431 ? 119.836 520.323 70.783 1.00 30.17 ? 485 LEU A CG 1 ATOM 3047 C CD1 . LEU A 1 431 ? 119.551 518.848 70.657 1.00 31.88 ? 485 LEU A CD1 1 ATOM 3048 C CD2 . LEU A 1 431 ? 119.208 520.787 72.058 1.00 36.34 ? 485 LEU A CD2 1 ATOM 3049 N N . VAL A 1 432 ? 120.528 523.727 70.711 1.00 14.45 ? 486 VAL A N 1 ATOM 3050 C CA . VAL A 1 432 ? 120.063 524.824 71.542 1.00 14.16 ? 486 VAL A CA 1 ATOM 3051 C C . VAL A 1 432 ? 118.701 524.446 72.144 1.00 17.65 ? 486 VAL A C 1 ATOM 3052 O O . VAL A 1 432 ? 117.845 523.955 71.438 1.00 15.33 ? 486 VAL A O 1 ATOM 3053 C CB . VAL A 1 432 ? 120.071 526.209 70.842 1.00 14.13 ? 486 VAL A CB 1 ATOM 3054 C CG1 . VAL A 1 432 ? 119.247 527.233 71.593 1.00 13.01 ? 486 VAL A CG1 1 ATOM 3055 C CG2 . VAL A 1 432 ? 121.478 526.695 70.658 1.00 12.46 ? 486 VAL A CG2 1 ATOM 3056 N N . ALA A 1 433 ? 118.530 524.675 73.444 1.00 17.01 ? 487 ALA A N 1 ATOM 3057 C CA . ALA A 1 433 ? 117.276 524.446 74.123 1.00 18.21 ? 487 ALA A CA 1 ATOM 3058 C C . ALA A 1 433 ? 116.720 525.752 74.655 1.00 24.10 ? 487 ALA A C 1 ATOM 3059 O O . ALA A 1 433 ? 117.448 526.565 75.202 1.00 26.35 ? 487 ALA A O 1 ATOM 3060 C CB . ALA A 1 433 ? 117.473 523.470 75.267 1.00 19.49 ? 487 ALA A CB 1 ATOM 3061 N N . ILE A 1 434 ? 115.419 525.937 74.511 1.00 20.30 ? 488 ILE A N 1 ATOM 3062 C CA . ILE A 1 434 ? 114.718 527.099 75.020 1.00 19.03 ? 488 ILE A CA 1 ATOM 3063 C C . ILE A 1 434 ? 114.522 526.979 76.548 1.00 26.32 ? 488 ILE A C 1 ATOM 3064 O O . ILE A 1 434 ? 114.171 525.901 77.064 1.00 26.51 ? 488 ILE A O 1 ATOM 3065 C CB . ILE A 1 434 ? 113.407 527.336 74.246 1.00 20.81 ? 488 ILE A CB 1 ATOM 3066 C CG1 . ILE A 1 434 ? 112.873 528.750 74.489 1.00 21.49 ? 488 ILE A CG1 1 ATOM 3067 C CG2 . ILE A 1 434 ? 112.364 526.278 74.569 1.00 21.31 ? 488 ILE A CG2 1 ATOM 3068 C CD1 . ILE A 1 434 ? 111.874 529.204 73.525 1.00 28.26 ? 488 ILE A CD1 1 ATOM 3069 N N . VAL A 1 435 ? 114.795 528.094 77.258 1.00 22.54 ? 489 VAL A N 1 ATOM 3070 C CA . VAL A 1 435 ? 114.672 528.244 78.712 1.00 21.41 ? 489 VAL A CA 1 ATOM 3071 C C . VAL A 1 435 ? 114.124 529.642 78.933 1.00 29.70 ? 489 VAL A C 1 ATOM 3072 O O . VAL A 1 435 ? 114.831 530.641 78.740 1.00 30.69 ? 489 VAL A O 1 ATOM 3073 C CB . VAL A 1 435 ? 116.004 528.043 79.480 1.00 23.29 ? 489 VAL A CB 1 ATOM 3074 C CG1 . VAL A 1 435 ? 115.782 528.183 80.970 1.00 21.94 ? 489 VAL A CG1 1 ATOM 3075 C CG2 . VAL A 1 435 ? 116.635 526.683 79.185 1.00 23.34 ? 489 VAL A CG2 1 ATOM 3076 N N . ASP A 1 436 ? 112.853 529.723 79.298 1.00 26.89 ? 490 ASP A N 1 ATOM 3077 C CA . ASP A 1 436 ? 112.198 531.011 79.484 1.00 25.76 ? 490 ASP A CA 1 ATOM 3078 C C . ASP A 1 436 ? 112.120 531.393 80.952 1.00 29.62 ? 490 ASP A C 1 ATOM 3079 O O . ASP A 1 436 ? 112.173 530.511 81.823 1.00 29.57 ? 490 ASP A O 1 ATOM 3080 C CB . ASP A 1 436 ? 110.772 530.972 78.919 1.00 26.40 ? 490 ASP A CB 1 ATOM 3081 C CG . ASP A 1 436 ? 110.644 530.762 77.431 1.00 25.82 ? 490 ASP A CG 1 ATOM 3082 O OD1 . ASP A 1 436 ? 111.653 530.894 76.720 1.00 25.93 ? 490 ASP A OD1 1 ATOM 3083 O OD2 . ASP A 1 436 ? 109.525 530.565 76.976 1.00 29.28 ? 490 ASP A OD2 1 ATOM 3084 N N . PRO A 1 437 ? 111.937 532.705 81.233 1.00 24.43 ? 491 PRO A N 1 ATOM 3085 C CA . PRO A 1 437 ? 111.869 533.157 82.626 1.00 24.86 ? 491 PRO A CA 1 ATOM 3086 C C . PRO A 1 437 ? 110.462 533.136 83.247 1.00 31.11 ? 491 PRO A C 1 ATOM 3087 O O . PRO A 1 437 ? 110.080 534.092 83.919 1.00 32.20 ? 491 PRO A O 1 ATOM 3088 C CB . PRO A 1 437 ? 112.405 534.584 82.531 1.00 25.22 ? 491 PRO A CB 1 ATOM 3089 C CG . PRO A 1 437 ? 111.945 535.039 81.219 1.00 27.64 ? 491 PRO A CG 1 ATOM 3090 C CD . PRO A 1 437 ? 111.925 533.859 80.313 1.00 23.02 ? 491 PRO A CD 1 ATOM 3091 N N . HIS A 1 438 ? 109.668 532.121 82.953 1.00 26.47 ? 492 HIS A N 1 ATOM 3092 C CA . HIS A 1 438 ? 108.375 531.951 83.608 1.00 25.75 ? 492 HIS A CA 1 ATOM 3093 C C . HIS A 1 438 ? 108.339 530.524 84.062 1.00 31.26 ? 492 HIS A C 1 ATOM 3094 O O . HIS A 1 438 ? 108.765 529.620 83.346 1.00 30.82 ? 492 HIS A O 1 ATOM 3095 C CB . HIS A 1 438 ? 107.155 532.391 82.796 1.00 25.79 ? 492 HIS A CB 1 ATOM 3096 C CG . HIS A 1 438 ? 107.059 531.777 81.443 1.00 28.28 ? 492 HIS A CG 1 ATOM 3097 N ND1 . HIS A 1 438 ? 107.396 532.485 80.320 1.00 29.57 ? 492 HIS A ND1 1 ATOM 3098 C CD2 . HIS A 1 438 ? 106.698 530.527 81.079 1.00 29.02 ? 492 HIS A CD2 1 ATOM 3099 C CE1 . HIS A 1 438 ? 107.193 531.664 79.301 1.00 28.90 ? 492 HIS A CE1 1 ATOM 3100 N NE2 . HIS A 1 438 ? 106.784 530.472 79.715 1.00 28.77 ? 492 HIS A NE2 1 ATOM 3101 N N . ILE A 1 439 ? 107.959 530.341 85.315 1.00 28.97 ? 493 ILE A N 1 ATOM 3102 C CA . ILE A 1 439 ? 108.026 529.058 85.976 1.00 28.12 ? 493 ILE A CA 1 ATOM 3103 C C . ILE A 1 439 ? 106.636 528.598 86.308 1.00 28.19 ? 493 ILE A C 1 ATOM 3104 O O . ILE A 1 439 ? 105.924 529.309 87.011 1.00 27.31 ? 493 ILE A O 1 ATOM 3105 C CB . ILE A 1 439 ? 108.887 529.263 87.236 1.00 30.91 ? 493 ILE A CB 1 ATOM 3106 C CG1 . ILE A 1 439 ? 110.247 529.918 86.880 1.00 31.53 ? 493 ILE A CG1 1 ATOM 3107 C CG2 . ILE A 1 439 ? 109.033 527.969 88.000 1.00 29.39 ? 493 ILE A CG2 1 ATOM 3108 C CD1 . ILE A 1 439 ? 111.098 529.135 85.804 1.00 36.80 ? 493 ILE A CD1 1 ATOM 3109 N N . LYS A 1 440 ? 106.254 527.414 85.832 1.00 21.85 ? 494 LYS A N 1 ATOM 3110 C CA . LYS A 1 440 ? 104.931 526.872 86.126 1.00 20.42 ? 494 LYS A CA 1 ATOM 3111 C C . LYS A 1 440 ? 104.706 526.710 87.619 1.00 24.42 ? 494 LYS A C 1 ATOM 3112 O O . LYS A 1 440 ? 105.554 526.138 88.301 1.00 25.54 ? 494 LYS A O 1 ATOM 3113 C CB . LYS A 1 440 ? 104.737 525.526 85.429 1.00 21.90 ? 494 LYS A CB 1 ATOM 3114 C CG . LYS A 1 440 ? 103.304 525.034 85.461 1.00 33.45 ? 494 LYS A CG 1 ATOM 3115 C CD . LYS A 1 440 ? 103.073 523.931 84.442 1.00 38.19 ? 494 LYS A CD 1 ATOM 3116 C CE . LYS A 1 440 ? 101.652 523.406 84.501 1.00 35.23 ? 494 LYS A CE 1 ATOM 3117 N NZ . LYS A 1 440 ? 100.924 523.620 83.209 1.00 38.73 ? 494 LYS A NZ 1 ATOM 3118 N N . VAL A 1 441 ? 103.590 527.254 88.136 1.00 21.07 ? 495 VAL A N 1 ATOM 3119 C CA . VAL A 1 441 ? 103.197 527.107 89.547 1.00 20.87 ? 495 VAL A CA 1 ATOM 3120 C C . VAL A 1 441 ? 102.713 525.672 89.717 1.00 25.32 ? 495 VAL A C 1 ATOM 3121 O O . VAL A 1 441 ? 101.585 525.355 89.367 1.00 25.44 ? 495 VAL A O 1 ATOM 3122 C CB . VAL A 1 441 ? 102.106 528.099 89.945 1.00 24.86 ? 495 VAL A CB 1 ATOM 3123 C CG1 . VAL A 1 441 ? 101.690 527.881 91.404 1.00 24.98 ? 495 VAL A CG1 1 ATOM 3124 C CG2 . VAL A 1 441 ? 102.579 529.528 89.725 1.00 24.75 ? 495 VAL A CG2 1 ATOM 3125 N N . ASP A 1 442 ? 103.598 524.802 90.154 1.00 24.06 ? 496 ASP A N 1 ATOM 3126 C CA . ASP A 1 442 ? 103.336 523.379 90.272 1.00 25.58 ? 496 ASP A CA 1 ATOM 3127 C C . ASP A 1 442 ? 104.206 522.872 91.401 1.00 30.15 ? 496 ASP A C 1 ATOM 3128 O O . ASP A 1 442 ? 105.437 522.970 91.357 1.00 27.25 ? 496 ASP A O 1 ATOM 3129 C CB . ASP A 1 442 ? 103.674 522.685 88.928 1.00 28.58 ? 496 ASP A CB 1 ATOM 3130 C CG . ASP A 1 442 ? 103.514 521.172 88.871 1.00 44.55 ? 496 ASP A CG 1 ATOM 3131 O OD1 . ASP A 1 442 ? 103.597 520.521 89.916 1.00 47.26 ? 496 ASP A OD1 1 ATOM 3132 O OD2 . ASP A 1 442 ? 103.367 520.642 87.773 1.00 54.22 ? 496 ASP A OD2 1 ATOM 3133 N N . SER A 1 443 ? 103.567 522.335 92.429 1.00 29.49 ? 497 SER A N 1 ATOM 3134 C CA . SER A 1 443 ? 104.303 521.870 93.603 1.00 28.94 ? 497 SER A CA 1 ATOM 3135 C C . SER A 1 443 ? 105.198 520.645 93.344 1.00 31.70 ? 497 SER A C 1 ATOM 3136 O O . SER A 1 443 ? 106.042 520.321 94.176 1.00 31.09 ? 497 SER A O 1 ATOM 3137 C CB . SER A 1 443 ? 103.354 521.631 94.771 1.00 31.89 ? 497 SER A CB 1 ATOM 3138 O OG . SER A 1 443 ? 102.496 520.535 94.511 1.00 40.54 ? 497 SER A OG 1 ATOM 3139 N N . GLY A 1 444 ? 105.027 519.995 92.200 1.00 27.53 ? 498 GLY A N 1 ATOM 3140 C CA . GLY A 1 444 ? 105.837 518.847 91.809 1.00 26.60 ? 498 GLY A CA 1 ATOM 3141 C C . GLY A 1 444 ? 107.055 519.237 91.001 1.00 28.84 ? 498 GLY A C 1 ATOM 3142 O O . GLY A 1 444 ? 107.887 518.375 90.695 1.00 28.47 ? 498 GLY A O 1 ATOM 3143 N N . TYR A 1 445 ? 107.177 520.543 90.664 1.00 24.20 ? 499 TYR A N 1 ATOM 3144 C CA . TYR A 1 445 ? 108.258 521.082 89.831 1.00 23.95 ? 499 TYR A CA 1 ATOM 3145 C C . TYR A 1 445 ? 109.315 521.703 90.722 1.00 29.32 ? 499 TYR A C 1 ATOM 3146 O O . TYR A 1 445 ? 109.077 522.753 91.314 1.00 29.49 ? 499 TYR A O 1 ATOM 3147 C CB . TYR A 1 445 ? 107.637 522.050 88.808 1.00 23.86 ? 499 TYR A CB 1 ATOM 3148 C CG . TYR A 1 445 ? 108.563 522.815 87.893 1.00 24.47 ? 499 TYR A CG 1 ATOM 3149 C CD1 . TYR A 1 445 ? 109.735 522.240 87.406 1.00 25.49 ? 499 TYR A CD1 1 ATOM 3150 C CD2 . TYR A 1 445 ? 108.219 524.083 87.435 1.00 25.49 ? 499 TYR A CD2 1 ATOM 3151 C CE1 . TYR A 1 445 ? 110.574 522.941 86.540 1.00 27.09 ? 499 TYR A CE1 1 ATOM 3152 C CE2 . TYR A 1 445 ? 109.034 524.782 86.553 1.00 26.55 ? 499 TYR A CE2 1 ATOM 3153 C CZ . TYR A 1 445 ? 110.222 524.219 86.124 1.00 37.43 ? 499 TYR A CZ 1 ATOM 3154 O OH . TYR A 1 445 ? 111.020 524.935 85.256 1.00 40.12 ? 499 TYR A OH 1 ATOM 3155 N N . ARG A 1 446 ? 110.476 521.039 90.843 1.00 27.06 ? 500 ARG A N 1 ATOM 3156 C CA . ARG A 1 446 ? 111.557 521.460 91.770 1.00 26.61 ? 500 ARG A CA 1 ATOM 3157 C C . ARG A 1 446 ? 112.009 522.912 91.608 1.00 26.28 ? 500 ARG A C 1 ATOM 3158 O O . ARG A 1 446 ? 112.369 523.569 92.578 1.00 23.33 ? 500 ARG A O 1 ATOM 3159 C CB . ARG A 1 446 ? 112.779 520.529 91.707 1.00 28.07 ? 500 ARG A CB 1 ATOM 3160 C CG . ARG A 1 446 ? 112.479 519.051 91.967 1.00 50.88 ? 500 ARG A CG 1 ATOM 3161 C CD . ARG A 1 446 ? 113.749 518.258 92.247 1.00 79.42 ? 500 ARG A CD 1 ATOM 3162 N NE . ARG A 1 446 ? 114.447 518.768 93.433 1.00 103.12 ? 500 ARG A NE 1 ATOM 3163 C CZ . ARG A 1 446 ? 115.686 519.257 93.441 1.00 126.38 ? 500 ARG A CZ 1 ATOM 3164 N NH1 . ARG A 1 446 ? 116.408 519.282 92.324 1.00 119.63 ? 500 ARG A NH1 1 ATOM 3165 N NH2 . ARG A 1 446 ? 116.219 519.712 94.567 1.00 114.22 ? 500 ARG A NH2 1 ATOM 3166 N N . VAL A 1 447 ? 111.992 523.415 90.383 1.00 24.32 ? 501 VAL A N 1 ATOM 3167 C CA . VAL A 1 447 ? 112.427 524.800 90.133 1.00 23.64 ? 501 VAL A CA 1 ATOM 3168 C C . VAL A 1 447 ? 111.454 525.736 90.808 1.00 27.61 ? 501 VAL A C 1 ATOM 3169 O O . VAL A 1 447 ? 111.881 526.688 91.493 1.00 26.24 ? 501 VAL A O 1 ATOM 3170 C CB . VAL A 1 447 ? 112.566 525.107 88.631 1.00 25.49 ? 501 VAL A CB 1 ATOM 3171 C CG1 . VAL A 1 447 ? 112.818 526.597 88.391 1.00 24.75 ? 501 VAL A CG1 1 ATOM 3172 C CG2 . VAL A 1 447 ? 113.653 524.253 87.993 1.00 24.70 ? 501 VAL A CG2 1 ATOM 3173 N N . HIS A 1 448 ? 110.142 525.445 90.637 1.00 23.81 ? 502 HIS A N 1 ATOM 3174 C CA . HIS A 1 448 ? 109.113 526.250 91.263 1.00 23.57 ? 502 HIS A CA 1 ATOM 3175 C C . HIS A 1 448 ? 109.249 526.168 92.771 1.00 33.57 ? 502 HIS A C 1 ATOM 3176 O O . HIS A 1 448 ? 109.260 527.208 93.423 1.00 35.49 ? 502 HIS A O 1 ATOM 3177 C CB . HIS A 1 448 ? 107.682 525.872 90.818 1.00 22.98 ? 502 HIS A CB 1 ATOM 3178 C CG . HIS A 1 448 ? 106.621 526.527 91.669 1.00 25.28 ? 502 HIS A CG 1 ATOM 3179 N ND1 . HIS A 1 448 ? 106.361 527.892 91.588 1.00 26.16 ? 502 HIS A ND1 1 ATOM 3180 C CD2 . HIS A 1 448 ? 105.844 526.003 92.644 1.00 25.73 ? 502 HIS A CD2 1 ATOM 3181 C CE1 . HIS A 1 448 ? 105.407 528.139 92.472 1.00 24.70 ? 502 HIS A CE1 1 ATOM 3182 N NE2 . HIS A 1 448 ? 105.054 527.036 93.117 1.00 25.20 ? 502 HIS A NE2 1 ATOM 3183 N N . GLU A 1 449 ? 109.382 524.954 93.322 1.00 32.62 ? 503 GLU A N 1 ATOM 3184 C CA . GLU A 1 449 ? 109.472 524.790 94.763 1.00 34.36 ? 503 GLU A CA 1 ATOM 3185 C C . GLU A 1 449 ? 110.637 525.556 95.373 1.00 40.23 ? 503 GLU A C 1 ATOM 3186 O O . GLU A 1 449 ? 110.441 526.276 96.359 1.00 40.81 ? 503 GLU A O 1 ATOM 3187 C CB . GLU A 1 449 ? 109.469 523.308 95.180 1.00 36.46 ? 503 GLU A CB 1 ATOM 3188 C CG . GLU A 1 449 ? 108.046 522.756 95.324 1.00 54.41 ? 503 GLU A CG 1 ATOM 3189 C CD . GLU A 1 449 ? 107.135 523.404 96.367 1.00 82.03 ? 503 GLU A CD 1 ATOM 3190 O OE1 . GLU A 1 449 ? 107.402 523.218 97.576 1.00 94.54 ? 503 GLU A OE1 1 ATOM 3191 O OE2 . GLU A 1 449 ? 106.160 524.096 95.984 1.00 67.60 ? 503 GLU A OE2 1 ATOM 3192 N N . GLU A 1 450 ? 111.819 525.461 94.755 1.00 36.51 ? 504 GLU A N 1 ATOM 3193 C CA . GLU A 1 450 ? 113.011 526.161 95.239 1.00 35.18 ? 504 GLU A CA 1 ATOM 3194 C C . GLU A 1 450 ? 112.855 527.682 95.204 1.00 34.85 ? 504 GLU A C 1 ATOM 3195 O O . GLU A 1 450 ? 113.144 528.335 96.214 1.00 34.57 ? 504 GLU A O 1 ATOM 3196 C CB . GLU A 1 450 ? 114.262 525.690 94.502 1.00 36.34 ? 504 GLU A CB 1 ATOM 3197 C CG . GLU A 1 450 ? 114.631 524.257 94.839 1.00 47.24 ? 504 GLU A CG 1 ATOM 3198 C CD . GLU A 1 450 ? 116.125 524.001 94.929 1.00 80.50 ? 504 GLU A CD 1 ATOM 3199 O OE1 . GLU A 1 450 ? 116.826 524.796 95.601 1.00 81.44 ? 504 GLU A OE1 1 ATOM 3200 O OE2 . GLU A 1 450 ? 116.596 523.007 94.327 1.00 76.84 ? 504 GLU A OE2 1 ATOM 3201 N N . LEU A 1 451 ? 112.327 528.225 94.098 1.00 27.82 ? 505 LEU A N 1 ATOM 3202 C CA . LEU A 1 451 ? 112.090 529.664 93.956 1.00 27.40 ? 505 LEU A CA 1 ATOM 3203 C C . LEU A 1 451 ? 111.018 530.197 94.911 1.00 32.91 ? 505 LEU A C 1 ATOM 3204 O O . LEU A 1 451 ? 111.158 531.298 95.451 1.00 31.78 ? 505 LEU A O 1 ATOM 3205 C CB . LEU A 1 451 ? 111.738 530.034 92.496 1.00 27.06 ? 505 LEU A CB 1 ATOM 3206 C CG . LEU A 1 451 ? 112.826 529.806 91.476 1.00 30.70 ? 505 LEU A CG 1 ATOM 3207 C CD1 . LEU A 1 451 ? 112.342 530.099 90.070 1.00 30.46 ? 505 LEU A CD1 1 ATOM 3208 C CD2 . LEU A 1 451 ? 113.975 530.675 91.748 1.00 33.86 ? 505 LEU A CD2 1 ATOM 3209 N N . ARG A 1 452 ? 109.918 529.441 95.068 1.00 31.19 ? 506 ARG A N 1 ATOM 3210 C CA . ARG A 1 452 ? 108.840 529.812 95.975 1.00 30.63 ? 506 ARG A CA 1 ATOM 3211 C C . ARG A 1 452 ? 109.398 529.848 97.399 1.00 34.76 ? 506 ARG A C 1 ATOM 3212 O O . ARG A 1 452 ? 109.182 530.837 98.106 1.00 33.85 ? 506 ARG A O 1 ATOM 3213 C CB . ARG A 1 452 ? 107.662 528.825 95.837 1.00 29.98 ? 506 ARG A CB 1 ATOM 3214 C CG . ARG A 1 452 ? 106.730 528.731 97.033 1.00 44.93 ? 506 ARG A CG 1 ATOM 3215 C CD . ARG A 1 452 ? 105.805 527.534 96.915 1.00 56.03 ? 506 ARG A CD 1 ATOM 3216 N NE . ARG A 1 452 ? 104.824 527.512 97.998 1.00 76.80 ? 506 ARG A NE 1 ATOM 3217 C CZ . ARG A 1 452 ? 103.716 528.249 98.031 1.00 100.30 ? 506 ARG A CZ 1 ATOM 3218 N NH1 . ARG A 1 452 ? 103.433 529.086 97.035 1.00 87.65 ? 506 ARG A NH1 1 ATOM 3219 N NH2 . ARG A 1 452 ? 102.885 528.161 99.063 1.00 91.12 ? 506 ARG A NH2 1 ATOM 3220 N N . ASN A 1 453 ? 110.123 528.778 97.795 1.00 31.61 ? 507 ASN A N 1 ATOM 3221 C CA . ASN A 1 453 ? 110.678 528.590 99.141 1.00 31.62 ? 507 ASN A CA 1 ATOM 3222 C C . ASN A 1 453 ? 111.718 529.625 99.523 1.00 40.07 ? 507 ASN A C 1 ATOM 3223 O O . ASN A 1 453 ? 111.831 529.964 100.707 1.00 41.33 ? 507 ASN A O 1 ATOM 3224 C CB . ASN A 1 453 ? 111.249 527.182 99.329 1.00 28.59 ? 507 ASN A CB 1 ATOM 3225 C CG . ASN A 1 453 ? 110.229 526.083 99.491 1.00 52.23 ? 507 ASN A CG 1 ATOM 3226 O OD1 . ASN A 1 453 ? 109.029 526.312 99.612 1.00 48.24 ? 507 ASN A OD1 1 ATOM 3227 N ND2 . ASN A 1 453 ? 110.701 524.853 99.506 1.00 49.65 ? 507 ASN A ND2 1 ATOM 3228 N N . HIS A 1 454 ? 112.492 530.113 98.534 1.00 37.04 ? 508 HIS A N 1 ATOM 3229 C CA . HIS A 1 454 ? 113.523 531.117 98.763 1.00 36.41 ? 508 HIS A CA 1 ATOM 3230 C C . HIS A 1 454 ? 113.047 532.553 98.488 1.00 35.92 ? 508 HIS A C 1 ATOM 3231 O O . HIS A 1 454 ? 113.835 533.486 98.643 1.00 34.88 ? 508 HIS A O 1 ATOM 3232 C CB . HIS A 1 454 ? 114.807 530.767 97.986 1.00 38.63 ? 508 HIS A CB 1 ATOM 3233 C CG . HIS A 1 454 ? 115.534 529.590 98.558 1.00 43.36 ? 508 HIS A CG 1 ATOM 3234 N ND1 . HIS A 1 454 ? 115.939 528.539 97.753 1.00 46.16 ? 508 HIS A ND1 1 ATOM 3235 C CD2 . HIS A 1 454 ? 115.860 529.311 99.846 1.00 45.74 ? 508 HIS A CD2 1 ATOM 3236 C CE1 . HIS A 1 454 ? 116.516 527.669 98.566 1.00 46.03 ? 508 HIS A CE1 1 ATOM 3237 N NE2 . HIS A 1 454 ? 116.478 528.086 99.841 1.00 46.09 ? 508 HIS A NE2 1 ATOM 3238 N N . GLY A 1 455 ? 111.759 532.712 98.160 1.00 31.54 ? 509 GLY A N 1 ATOM 3239 C CA . GLY A 1 455 ? 111.101 533.989 97.879 1.00 31.40 ? 509 GLY A CA 1 ATOM 3240 C C . GLY A 1 455 ? 111.741 534.755 96.736 1.00 35.19 ? 509 GLY A C 1 ATOM 3241 O O . GLY A 1 455 ? 111.840 535.981 96.775 1.00 36.61 ? 509 GLY A O 1 ATOM 3242 N N . LEU A 1 456 ? 112.165 534.046 95.702 1.00 28.21 ? 510 LEU A N 1 ATOM 3243 C CA . LEU A 1 456 ? 112.901 534.666 94.611 1.00 26.65 ? 510 LEU A CA 1 ATOM 3244 C C . LEU A 1 456 ? 112.039 535.133 93.452 1.00 30.79 ? 510 LEU A C 1 ATOM 3245 O O . LEU A 1 456 ? 112.564 535.644 92.462 1.00 31.00 ? 510 LEU A O 1 ATOM 3246 C CB . LEU A 1 456 ? 114.023 533.739 94.139 1.00 25.78 ? 510 LEU A CB 1 ATOM 3247 C CG . LEU A 1 456 ? 115.148 533.505 95.146 1.00 28.55 ? 510 LEU A CG 1 ATOM 3248 C CD1 . LEU A 1 456 ? 116.104 532.488 94.645 1.00 28.30 ? 510 LEU A CD1 1 ATOM 3249 C CD2 . LEU A 1 456 ? 115.889 534.772 95.439 1.00 28.94 ? 510 LEU A CD2 1 ATOM 3250 N N . TYR A 1 457 ? 110.722 535.047 93.605 1.00 26.10 ? 511 TYR A N 1 ATOM 3251 C CA . TYR A 1 457 ? 109.788 535.494 92.589 1.00 23.72 ? 511 TYR A CA 1 ATOM 3252 C C . TYR A 1 457 ? 109.488 536.969 92.703 1.00 30.04 ? 511 TYR A C 1 ATOM 3253 O O . TYR A 1 457 ? 109.568 537.534 93.792 1.00 30.14 ? 511 TYR A O 1 ATOM 3254 C CB . TYR A 1 457 ? 108.478 534.728 92.728 1.00 23.50 ? 511 TYR A CB 1 ATOM 3255 C CG . TYR A 1 457 ? 108.508 533.319 92.199 1.00 23.97 ? 511 TYR A CG 1 ATOM 3256 C CD1 . TYR A 1 457 ? 109.013 533.041 90.932 1.00 26.07 ? 511 TYR A CD1 1 ATOM 3257 C CD2 . TYR A 1 457 ? 107.914 532.279 92.905 1.00 24.34 ? 511 TYR A CD2 1 ATOM 3258 C CE1 . TYR A 1 457 ? 109.011 531.748 90.423 1.00 27.26 ? 511 TYR A CE1 1 ATOM 3259 C CE2 . TYR A 1 457 ? 107.876 530.987 92.393 1.00 24.78 ? 511 TYR A CE2 1 ATOM 3260 C CZ . TYR A 1 457 ? 108.420 530.728 91.148 1.00 29.40 ? 511 TYR A CZ 1 ATOM 3261 O OH . TYR A 1 457 ? 108.388 529.468 90.627 1.00 25.38 ? 511 TYR A OH 1 ATOM 3262 N N . VAL A 1 458 ? 109.077 537.584 91.580 1.00 29.15 ? 512 VAL A N 1 ATOM 3263 C CA . VAL A 1 458 ? 108.564 538.953 91.559 1.00 28.82 ? 512 VAL A CA 1 ATOM 3264 C C . VAL A 1 458 ? 107.250 538.938 92.414 1.00 31.33 ? 512 VAL A C 1 ATOM 3265 O O . VAL A 1 458 ? 106.459 537.986 92.356 1.00 28.85 ? 512 VAL A O 1 ATOM 3266 C CB . VAL A 1 458 ? 108.318 539.494 90.124 1.00 32.33 ? 512 VAL A CB 1 ATOM 3267 C CG1 . VAL A 1 458 ? 107.639 540.861 90.165 1.00 31.75 ? 512 VAL A CG1 1 ATOM 3268 C CG2 . VAL A 1 458 ? 109.624 539.602 89.348 1.00 32.22 ? 512 VAL A CG2 1 ATOM 3269 N N . LYS A 1 459 ? 107.056 539.983 93.222 1.00 28.55 ? 513 LYS A N 1 ATOM 3270 C CA . LYS A 1 459 ? 105.928 540.067 94.157 1.00 28.00 ? 513 LYS A CA 1 ATOM 3271 C C . LYS A 1 459 ? 104.910 541.105 93.759 1.00 32.69 ? 513 LYS A C 1 ATOM 3272 O O . LYS A 1 459 ? 105.226 541.980 92.957 1.00 30.39 ? 513 LYS A O 1 ATOM 3273 C CB . LYS A 1 459 ? 106.479 540.324 95.583 1.00 28.29 ? 513 LYS A CB 1 ATOM 3274 C CG . LYS A 1 459 ? 107.255 539.100 96.018 1.00 35.55 ? 513 LYS A CG 1 ATOM 3275 C CD . LYS A 1 459 ? 107.734 539.025 97.424 1.00 51.09 ? 513 LYS A CD 1 ATOM 3276 C CE . LYS A 1 459 ? 108.308 537.635 97.635 1.00 64.20 ? 513 LYS A CE 1 ATOM 3277 N NZ . LYS A 1 459 ? 107.251 536.653 98.023 1.00 68.37 ? 513 LYS A NZ 1 ATOM 3278 N N . THR A 1 460 ? 103.681 541.016 94.308 1.00 32.12 ? 514 THR A N 1 ATOM 3279 C CA . THR A 1 460 ? 102.685 542.084 94.124 1.00 32.54 ? 514 THR A CA 1 ATOM 3280 C C . THR A 1 460 ? 102.878 542.976 95.345 1.00 34.10 ? 514 THR A C 1 ATOM 3281 O O . THR A 1 460 ? 103.649 542.599 96.231 1.00 31.47 ? 514 THR A O 1 ATOM 3282 C CB . THR A 1 460 ? 101.251 541.542 94.074 1.00 43.18 ? 514 THR A CB 1 ATOM 3283 O OG1 . THR A 1 460 ? 101.027 540.665 95.179 1.00 48.32 ? 514 THR A OG1 1 ATOM 3284 C CG2 . THR A 1 460 ? 100.958 540.832 92.798 1.00 38.30 ? 514 THR A CG2 1 ATOM 3285 N N . ARG A 1 461 ? 102.149 544.099 95.444 1.00 31.59 ? 515 ARG A N 1 ATOM 3286 C CA . ARG A 1 461 ? 102.236 544.961 96.635 1.00 32.21 ? 515 ARG A CA 1 ATOM 3287 C C . ARG A 1 461 ? 101.884 544.308 97.983 1.00 38.18 ? 515 ARG A C 1 ATOM 3288 O O . ARG A 1 461 ? 102.508 544.644 98.986 1.00 36.91 ? 515 ARG A O 1 ATOM 3289 C CB . ARG A 1 461 ? 101.400 546.197 96.467 1.00 31.33 ? 515 ARG A CB 1 ATOM 3290 C CG . ARG A 1 461 ? 102.046 547.172 95.525 1.00 37.32 ? 515 ARG A CG 1 ATOM 3291 C CD . ARG A 1 461 ? 101.222 548.427 95.459 1.00 38.83 ? 515 ARG A CD 1 ATOM 3292 N NE . ARG A 1 461 ? 101.303 549.207 96.696 1.00 38.54 ? 515 ARG A NE 1 ATOM 3293 C CZ . ARG A 1 461 ? 100.529 550.252 96.977 1.00 51.91 ? 515 ARG A CZ 1 ATOM 3294 N NH1 . ARG A 1 461 ? 99.601 550.650 96.117 1.00 39.72 ? 515 ARG A NH1 1 ATOM 3295 N NH2 . ARG A 1 461 ? 100.677 550.907 98.120 1.00 42.92 ? 515 ARG A NH2 1 ATOM 3296 N N . ASP A 1 462 ? 100.919 543.371 98.012 1.00 36.76 ? 516 ASP A N 1 ATOM 3297 C CA . ASP A 1 462 ? 100.544 542.695 99.263 1.00 37.00 ? 516 ASP A CA 1 ATOM 3298 C C . ASP A 1 462 ? 101.594 541.670 99.779 1.00 41.17 ? 516 ASP A C 1 ATOM 3299 O O . ASP A 1 462 ? 101.395 541.075 100.846 1.00 41.75 ? 516 ASP A O 1 ATOM 3300 C CB . ASP A 1 462 ? 99.143 542.061 99.159 1.00 38.85 ? 516 ASP A CB 1 ATOM 3301 C CG . ASP A 1 462 ? 98.960 541.061 98.050 1.00 54.13 ? 516 ASP A CG 1 ATOM 3302 O OD1 . ASP A 1 462 ? 99.918 540.329 97.750 1.00 55.77 ? 516 ASP A OD1 1 ATOM 3303 O OD2 . ASP A 1 462 ? 97.843 540.987 97.501 1.00 63.12 ? 516 ASP A OD2 1 ATOM 3304 N N . GLY A 1 463 ? 102.688 541.485 99.034 1.00 36.19 ? 517 GLY A N 1 ATOM 3305 C CA . GLY A 1 463 ? 103.775 540.588 99.411 1.00 35.52 ? 517 GLY A CA 1 ATOM 3306 C C . GLY A 1 463 ? 103.715 539.180 98.848 1.00 39.62 ? 517 GLY A C 1 ATOM 3307 O O . GLY A 1 463 ? 104.675 538.419 99.013 1.00 40.19 ? 517 GLY A O 1 ATOM 3308 N N . SER A 1 464 ? 102.611 538.808 98.186 1.00 35.51 ? 518 SER A N 1 ATOM 3309 C CA . SER A 1 464 ? 102.527 537.470 97.619 1.00 35.65 ? 518 SER A CA 1 ATOM 3310 C C . SER A 1 464 ? 103.206 537.387 96.220 1.00 39.11 ? 518 SER A C 1 ATOM 3311 O O . SER A 1 464 ? 103.442 538.407 95.558 1.00 37.53 ? 518 SER A O 1 ATOM 3312 C CB . SER A 1 464 ? 101.092 536.948 97.629 1.00 39.68 ? 518 SER A CB 1 ATOM 3313 O OG . SER A 1 464 ? 100.164 537.838 97.034 1.00 50.89 ? 518 SER A OG 1 ATOM 3314 N N . ASP A 1 465 ? 103.576 536.171 95.823 1.00 35.70 ? 519 ASP A N 1 ATOM 3315 C CA . ASP A 1 465 ? 104.224 535.910 94.546 1.00 35.18 ? 519 ASP A CA 1 ATOM 3316 C C . ASP A 1 465 ? 103.272 536.217 93.396 1.00 39.24 ? 519 ASP A C 1 ATOM 3317 O O . ASP A 1 465 ? 102.147 535.722 93.370 1.00 36.59 ? 519 ASP A O 1 ATOM 3318 C CB . ASP A 1 465 ? 104.754 534.455 94.474 1.00 35.70 ? 519 ASP A CB 1 ATOM 3319 C CG . ASP A 1 465 ? 105.843 534.144 95.500 1.00 40.45 ? 519 ASP A CG 1 ATOM 3320 O OD1 . ASP A 1 465 ? 106.574 535.068 95.891 1.00 38.81 ? 519 ASP A OD1 1 ATOM 3321 O OD2 . ASP A 1 465 ? 105.977 532.969 95.884 1.00 48.61 ? 519 ASP A OD2 1 ATOM 3322 N N . TYR A 1 466 ? 103.728 537.062 92.459 1.00 38.63 ? 520 TYR A N 1 ATOM 3323 C CA . TYR A 1 466 ? 102.979 537.442 91.260 1.00 39.38 ? 520 TYR A CA 1 ATOM 3324 C C . TYR A 1 466 ? 102.697 536.195 90.453 1.00 41.58 ? 520 TYR A C 1 ATOM 3325 O O . TYR A 1 466 ? 103.600 535.381 90.272 1.00 40.76 ? 520 TYR A O 1 ATOM 3326 C CB . TYR A 1 466 ? 103.836 538.371 90.396 1.00 41.38 ? 520 TYR A CB 1 ATOM 3327 C CG . TYR A 1 466 ? 103.104 538.996 89.238 1.00 45.43 ? 520 TYR A CG 1 ATOM 3328 C CD1 . TYR A 1 466 ? 102.990 538.334 88.013 1.00 47.66 ? 520 TYR A CD1 1 ATOM 3329 C CD2 . TYR A 1 466 ? 102.572 540.274 89.338 1.00 47.91 ? 520 TYR A CD2 1 ATOM 3330 C CE1 . TYR A 1 466 ? 102.291 538.905 86.942 1.00 49.24 ? 520 TYR A CE1 1 ATOM 3331 C CE2 . TYR A 1 466 ? 101.936 540.882 88.257 1.00 49.85 ? 520 TYR A CE2 1 ATOM 3332 C CZ . TYR A 1 466 ? 101.795 540.197 87.060 1.00 58.40 ? 520 TYR A CZ 1 ATOM 3333 O OH . TYR A 1 466 ? 101.165 540.829 86.013 1.00 61.05 ? 520 TYR A OH 1 ATOM 3334 N N . GLU A 1 467 ? 101.463 536.043 89.967 1.00 38.03 ? 521 GLU A N 1 ATOM 3335 C CA . GLU A 1 467 ? 101.092 534.908 89.121 1.00 38.12 ? 521 GLU A CA 1 ATOM 3336 C C . GLU A 1 467 ? 100.422 535.430 87.874 1.00 44.58 ? 521 GLU A C 1 ATOM 3337 O O . GLU A 1 467 ? 99.492 536.228 87.960 1.00 43.23 ? 521 GLU A O 1 ATOM 3338 C CB . GLU A 1 467 ? 100.214 533.880 89.857 1.00 39.21 ? 521 GLU A CB 1 ATOM 3339 C CG . GLU A 1 467 ? 100.873 533.316 91.114 1.00 48.85 ? 521 GLU A CG 1 ATOM 3340 C CD . GLU A 1 467 ? 100.315 532.034 91.704 1.00 64.93 ? 521 GLU A CD 1 ATOM 3341 O OE1 . GLU A 1 467 ? 99.344 531.472 91.142 1.00 51.91 ? 521 GLU A OE1 1 ATOM 3342 O OE2 . GLU A 1 467 ? 100.892 531.566 92.713 1.00 54.56 ? 521 GLU A OE2 1 ATOM 3343 N N . GLY A 1 468 ? 100.957 535.048 86.732 1.00 44.54 ? 522 GLY A N 1 ATOM 3344 C CA . GLY A 1 468 ? 100.365 535.415 85.469 1.00 46.98 ? 522 GLY A CA 1 ATOM 3345 C C . GLY A 1 468 ? 99.833 534.179 84.796 1.00 59.30 ? 522 GLY A C 1 ATOM 3346 O O . GLY A 1 468 ? 99.938 533.064 85.318 1.00 57.48 ? 522 GLY A O 1 ATOM 3347 N N . TRP A 1 469 ? 99.271 534.362 83.616 1.00 64.37 ? 523 TRP A N 1 ATOM 3348 C CA . TRP A 1 469 ? 98.873 533.248 82.775 1.00 67.59 ? 523 TRP A CA 1 ATOM 3349 C C . TRP A 1 469 ? 99.889 533.288 81.650 1.00 74.66 ? 523 TRP A C 1 ATOM 3350 O O . TRP A 1 469 ? 100.212 534.381 81.180 1.00 75.19 ? 523 TRP A O 1 ATOM 3351 C CB . TRP A 1 469 ? 97.380 533.290 82.404 1.00 67.34 ? 523 TRP A CB 1 ATOM 3352 C CG . TRP A 1 469 ? 96.571 532.571 83.456 1.00 69.32 ? 523 TRP A CG 1 ATOM 3353 C CD1 . TRP A 1 469 ? 95.976 531.351 83.316 1.00 72.46 ? 523 TRP A CD1 1 ATOM 3354 C CD2 . TRP A 1 469 ? 96.453 532.915 84.865 1.00 69.48 ? 523 TRP A CD2 1 ATOM 3355 N NE1 . TRP A 1 469 ? 95.419 530.951 84.515 1.00 72.41 ? 523 TRP A NE1 1 ATOM 3356 C CE2 . TRP A 1 469 ? 95.712 531.884 85.486 1.00 74.00 ? 523 TRP A CE2 1 ATOM 3357 C CE3 . TRP A 1 469 ? 96.837 534.028 85.648 1.00 70.65 ? 523 TRP A CE3 1 ATOM 3358 C CZ2 . TRP A 1 469 ? 95.358 531.928 86.850 1.00 73.26 ? 523 TRP A CZ2 1 ATOM 3359 C CZ3 . TRP A 1 469 ? 96.524 534.050 87.004 1.00 72.01 ? 523 TRP A CZ3 1 ATOM 3360 C CH2 . TRP A 1 469 ? 95.784 533.018 87.589 1.00 72.74 ? 523 TRP A CH2 1 ATOM 3361 N N . CYS A 1 470 ? 100.584 532.162 81.406 1.00 71.90 ? 524 CYS A N 1 ATOM 3362 C CA . CYS A 1 470 ? 101.674 532.109 80.420 1.00 71.97 ? 524 CYS A CA 1 ATOM 3363 C C . CYS A 1 470 ? 101.748 530.734 79.702 1.00 75.68 ? 524 CYS A C 1 ATOM 3364 O O . CYS A 1 470 ? 100.799 529.950 79.830 1.00 75.98 ? 524 CYS A O 1 ATOM 3365 C CB . CYS A 1 470 ? 102.995 532.480 81.086 1.00 72.31 ? 524 CYS A CB 1 ATOM 3366 S SG . CYS A 1 470 ? 103.989 533.640 80.125 1.00 76.19 ? 524 CYS A SG 1 ATOM 3367 H H . CYS A 1 470 ? 100.416 531.273 81.867 1.00 72.08 ? 524 CYS A H 1 ATOM 3368 H HA . CYS A 1 470 ? 101.500 532.858 79.650 1.00 72.24 ? 524 CYS A HA 1 ATOM 3369 H HB2 . CYS A 1 470 ? 102.783 532.949 82.046 1.00 72.54 ? 524 CYS A HB2 1 ATOM 3370 H HB3 . CYS A 1 470 ? 103.597 531.587 81.246 1.00 72.35 ? 524 CYS A HB3 1 ATOM 3371 H HG . CYS A 1 470 ? 103.658 533.411 78.850 1.00 75.89 ? 524 CYS A HG 1 ATOM 3372 N N . TRP A 1 471 ? 102.853 530.445 78.937 1.00 70.59 ? 525 TRP A N 1 ATOM 3373 C CA . TRP A 1 471 ? 103.039 529.162 78.211 1.00 69.24 ? 525 TRP A CA 1 ATOM 3374 C C . TRP A 1 471 ? 102.631 527.929 79.063 1.00 71.45 ? 525 TRP A C 1 ATOM 3375 O O . TRP A 1 471 ? 101.888 527.087 78.561 1.00 71.03 ? 525 TRP A O 1 ATOM 3376 C CB . TRP A 1 471 ? 104.470 529.007 77.624 1.00 67.23 ? 525 TRP A CB 1 ATOM 3377 C CG . TRP A 1 471 ? 104.691 529.746 76.335 1.00 67.72 ? 525 TRP A CG 1 ATOM 3378 H H . TRP A 1 471 ? 103.618 531.098 78.799 1.00 70.84 ? 525 TRP A H 1 ATOM 3379 H HA . TRP A 1 471 ? 102.361 529.179 77.358 1.00 69.62 ? 525 TRP A HA 1 ATOM 3380 N N . PRO A 1 472 ? 102.944 527.876 80.375 1.00 66.71 ? 526 PRO A N 1 ATOM 3381 C CA . PRO A 1 472 ? 102.505 526.742 81.197 1.00 65.82 ? 526 PRO A CA 1 ATOM 3382 C C . PRO A 1 472 ? 101.272 527.044 82.113 1.00 66.25 ? 526 PRO A C 1 ATOM 3383 O O . PRO A 1 472 ? 101.122 526.402 83.158 1.00 66.21 ? 526 PRO A O 1 ATOM 3384 C CB . PRO A 1 472 ? 103.775 526.450 82.019 1.00 67.84 ? 526 PRO A CB 1 ATOM 3385 C CG . PRO A 1 472 ? 104.655 527.724 81.912 1.00 72.59 ? 526 PRO A CG 1 ATOM 3386 C CD . PRO A 1 472 ? 103.834 528.734 81.171 1.00 68.22 ? 526 PRO A CD 1 ATOM 3387 H HA . PRO A 1 472 ? 102.290 525.859 80.596 1.00 65.96 ? 526 PRO A HA 1 ATOM 3388 H HB2 . PRO A 1 472 ? 103.511 526.331 83.065 1.00 68.11 ? 526 PRO A HB2 1 ATOM 3389 H HB3 . PRO A 1 472 ? 104.286 525.566 81.643 1.00 67.70 ? 526 PRO A HB3 1 ATOM 3390 H HG2 . PRO A 1 472 ? 104.889 528.084 82.913 1.00 72.63 ? 526 PRO A HG2 1 ATOM 3391 H HG3 . PRO A 1 472 ? 105.569 527.500 81.364 1.00 72.71 ? 526 PRO A HG3 1 ATOM 3392 H HD2 . PRO A 1 472 ? 103.260 529.340 81.870 1.00 68.37 ? 526 PRO A HD2 1 ATOM 3393 H HD3 . PRO A 1 472 ? 104.477 529.343 80.541 1.00 68.13 ? 526 PRO A HD3 1 ATOM 3394 N N . GLY A 1 473 ? 100.387 527.979 81.731 1.00 59.41 ? 527 GLY A N 1 ATOM 3395 C CA . GLY A 1 473 ? 99.215 528.330 82.548 1.00 57.74 ? 527 GLY A CA 1 ATOM 3396 C C . GLY A 1 473 ? 99.593 529.274 83.673 1.00 56.54 ? 527 GLY A C 1 ATOM 3397 O O . GLY A 1 473 ? 100.268 530.261 83.387 1.00 56.24 ? 527 GLY A O 1 ATOM 3398 H H . GLY A 1 473 ? 100.428 528.497 80.860 1.00 59.14 ? 527 GLY A H 1 ATOM 3399 H HA2 . GLY A 1 473 ? 98.476 528.830 81.922 1.00 57.98 ? 527 GLY A HA2 1 ATOM 3400 H HA3 . GLY A 1 473 ? 98.757 527.438 82.973 1.00 57.83 ? 527 GLY A HA3 1 ATOM 3401 N N . SER A 1 474 ? 99.193 528.989 84.970 1.00 48.64 ? 528 SER A N 1 ATOM 3402 C CA . SER A 1 474 ? 99.599 529.835 86.116 1.00 44.90 ? 528 SER A CA 1 ATOM 3403 C C . SER A 1 474 ? 101.112 529.700 86.280 1.00 43.79 ? 528 SER A C 1 ATOM 3404 O O . SER A 1 474 ? 101.641 528.599 86.425 1.00 43.30 ? 528 SER A O 1 ATOM 3405 C CB . SER A 1 474 ? 98.846 529.459 87.384 1.00 46.87 ? 528 SER A CB 1 ATOM 3406 O OG . SER A 1 474 ? 99.410 530.045 88.550 1.00 55.44 ? 528 SER A OG 1 ATOM 3407 N N . ALA A 1 475 ? 101.807 530.822 86.133 1.00 37.63 ? 529 ALA A N 1 ATOM 3408 C CA . ALA A 1 475 ? 103.262 530.902 86.165 1.00 35.26 ? 529 ALA A CA 1 ATOM 3409 C C . ALA A 1 475 ? 103.702 532.073 86.972 1.00 34.96 ? 529 ALA A C 1 ATOM 3410 O O . ALA A 1 475 ? 102.994 533.084 87.037 1.00 34.03 ? 529 ALA A O 1 ATOM 3411 C CB . ALA A 1 475 ? 103.801 531.041 84.740 1.00 35.89 ? 529 ALA A CB 1 ATOM 3412 N N . SER A 1 476 ? 104.880 531.941 87.593 1.00 30.79 ? 530 SER A N 1 ATOM 3413 C CA . SER A 1 476 ? 105.519 533.028 88.323 1.00 29.42 ? 530 SER A CA 1 ATOM 3414 C C . SER A 1 476 ? 106.811 533.440 87.637 1.00 31.94 ? 530 SER A C 1 ATOM 3415 O O . SER A 1 476 ? 107.355 532.702 86.801 1.00 31.08 ? 530 SER A O 1 ATOM 3416 C CB . SER A 1 476 ? 105.705 532.701 89.793 1.00 30.88 ? 530 SER A CB 1 ATOM 3417 O OG . SER A 1 476 ? 104.463 532.702 90.474 1.00 33.52 ? 530 SER A OG 1 ATOM 3418 N N . TYR A 1 477 ? 107.262 534.656 87.964 1.00 27.79 ? 531 TYR A N 1 ATOM 3419 C CA . TYR A 1 477 ? 108.380 535.302 87.300 1.00 26.79 ? 531 TYR A CA 1 ATOM 3420 C C . TYR A 1 477 ? 109.533 535.493 88.238 1.00 29.42 ? 531 TYR A C 1 ATOM 3421 O O . TYR A 1 477 ? 109.406 536.242 89.203 1.00 29.60 ? 531 TYR A O 1 ATOM 3422 C CB . TYR A 1 477 ? 107.899 536.634 86.722 1.00 27.22 ? 531 TYR A CB 1 ATOM 3423 C CG . TYR A 1 477 ? 106.853 536.389 85.665 1.00 29.91 ? 531 TYR A CG 1 ATOM 3424 C CD1 . TYR A 1 477 ? 105.505 536.250 86.005 1.00 31.17 ? 531 TYR A CD1 1 ATOM 3425 C CD2 . TYR A 1 477 ? 107.220 536.115 84.353 1.00 31.39 ? 531 TYR A CD2 1 ATOM 3426 C CE1 . TYR A 1 477 ? 104.548 535.908 85.050 1.00 28.81 ? 531 TYR A CE1 1 ATOM 3427 C CE2 . TYR A 1 477 ? 106.274 535.764 83.394 1.00 32.35 ? 531 TYR A CE2 1 ATOM 3428 C CZ . TYR A 1 477 ? 104.936 535.666 83.747 1.00 38.76 ? 531 TYR A CZ 1 ATOM 3429 O OH . TYR A 1 477 ? 103.989 535.349 82.799 1.00 43.98 ? 531 TYR A OH 1 ATOM 3430 N N . PRO A 1 478 ? 110.661 534.810 88.027 1.00 23.55 ? 532 PRO A N 1 ATOM 3431 C CA . PRO A 1 478 ? 111.794 535.013 88.924 1.00 22.63 ? 532 PRO A CA 1 ATOM 3432 C C . PRO A 1 478 ? 112.283 536.459 88.844 1.00 28.04 ? 532 PRO A C 1 ATOM 3433 O O . PRO A 1 478 ? 112.271 537.095 87.775 1.00 28.35 ? 532 PRO A O 1 ATOM 3434 C CB . PRO A 1 478 ? 112.841 534.063 88.373 1.00 24.41 ? 532 PRO A CB 1 ATOM 3435 C CG . PRO A 1 478 ? 112.110 533.078 87.574 1.00 29.40 ? 532 PRO A CG 1 ATOM 3436 C CD . PRO A 1 478 ? 111.000 533.858 86.957 1.00 25.61 ? 532 PRO A CD 1 ATOM 3437 N N . ASP A 1 479 ? 112.672 537.012 89.987 1.00 22.53 ? 533 ASP A N 1 ATOM 3438 C CA . ASP A 1 479 ? 113.133 538.387 89.988 1.00 19.47 ? 533 ASP A CA 1 ATOM 3439 C C . ASP A 1 479 ? 114.608 538.450 89.596 1.00 20.87 ? 533 ASP A C 1 ATOM 3440 O O . ASP A 1 479 ? 115.500 538.467 90.454 1.00 18.31 ? 533 ASP A O 1 ATOM 3441 C CB . ASP A 1 479 ? 112.853 539.064 91.321 1.00 19.54 ? 533 ASP A CB 1 ATOM 3442 C CG . ASP A 1 479 ? 113.362 540.488 91.361 1.00 25.48 ? 533 ASP A CG 1 ATOM 3443 O OD1 . ASP A 1 479 ? 113.658 541.053 90.278 1.00 27.14 ? 533 ASP A OD1 1 ATOM 3444 O OD2 . ASP A 1 479 ? 113.454 541.045 92.460 1.00 28.44 ? 533 ASP A OD2 1 ATOM 3445 N N . PHE A 1 480 ? 114.860 538.534 88.290 1.00 16.02 ? 534 PHE A N 1 ATOM 3446 C CA . PHE A 1 480 ? 116.227 538.588 87.773 1.00 14.62 ? 534 PHE A CA 1 ATOM 3447 C C . PHE A 1 480 ? 116.995 539.884 88.182 1.00 19.57 ? 534 PHE A C 1 ATOM 3448 O O . PHE A 1 480 ? 118.215 539.964 87.980 1.00 17.29 ? 534 PHE A O 1 ATOM 3449 C CB . PHE A 1 480 ? 116.244 538.364 86.250 1.00 15.26 ? 534 PHE A CB 1 ATOM 3450 C CG . PHE A 1 480 ? 116.016 536.925 85.857 1.00 15.41 ? 534 PHE A CG 1 ATOM 3451 C CD1 . PHE A 1 480 ? 114.736 536.420 85.726 1.00 17.57 ? 534 PHE A CD1 1 ATOM 3452 C CD2 . PHE A 1 480 ? 117.090 536.067 85.644 1.00 18.53 ? 534 PHE A CD2 1 ATOM 3453 C CE1 . PHE A 1 480 ? 114.526 535.084 85.372 1.00 19.53 ? 534 PHE A CE1 1 ATOM 3454 C CE2 . PHE A 1 480 ? 116.883 534.724 85.299 1.00 21.26 ? 534 PHE A CE2 1 ATOM 3455 C CZ . PHE A 1 480 ? 115.596 534.241 85.164 1.00 19.28 ? 534 PHE A CZ 1 ATOM 3456 N N . THR A 1 481 ? 116.301 540.893 88.783 1.00 16.53 ? 535 THR A N 1 ATOM 3457 C CA . THR A 1 481 ? 117.001 542.094 89.270 1.00 15.98 ? 535 THR A CA 1 ATOM 3458 C C . THR A 1 481 ? 117.766 541.764 90.557 1.00 20.57 ? 535 THR A C 1 ATOM 3459 O O . THR A 1 481 ? 118.672 542.497 90.957 1.00 20.07 ? 535 THR A O 1 ATOM 3460 C CB . THR A 1 481 ? 116.063 543.314 89.453 1.00 20.72 ? 535 THR A CB 1 ATOM 3461 O OG1 . THR A 1 481 ? 115.224 543.141 90.593 1.00 27.06 ? 535 THR A OG1 1 ATOM 3462 C CG2 . THR A 1 481 ? 115.207 543.583 88.247 1.00 11.68 ? 535 THR A CG2 1 ATOM 3463 N N . ASN A 1 482 ? 117.384 540.664 91.218 1.00 19.41 ? 536 ASN A N 1 ATOM 3464 C CA . ASN A 1 482 ? 118.008 540.243 92.475 1.00 18.92 ? 536 ASN A CA 1 ATOM 3465 C C . ASN A 1 482 ? 119.302 539.495 92.171 1.00 24.69 ? 536 ASN A C 1 ATOM 3466 O O . ASN A 1 482 ? 119.245 538.478 91.482 1.00 25.56 ? 536 ASN A O 1 ATOM 3467 C CB . ASN A 1 482 ? 117.031 539.420 93.269 1.00 13.15 ? 536 ASN A CB 1 ATOM 3468 C CG . ASN A 1 482 ? 117.523 538.897 94.576 1.00 23.00 ? 536 ASN A CG 1 ATOM 3469 O OD1 . ASN A 1 482 ? 118.713 538.786 94.820 1.00 21.29 ? 536 ASN A OD1 1 ATOM 3470 N ND2 . ASN A 1 482 ? 116.584 538.468 95.410 1.00 12.31 ? 536 ASN A ND2 1 ATOM 3471 N N . PRO A 1 483 ? 120.478 539.971 92.655 1.00 20.95 ? 537 PRO A N 1 ATOM 3472 C CA . PRO A 1 483 ? 121.732 539.278 92.332 1.00 20.91 ? 537 PRO A CA 1 ATOM 3473 C C . PRO A 1 483 ? 121.753 537.838 92.784 1.00 25.91 ? 537 PRO A C 1 ATOM 3474 O O . PRO A 1 483 ? 122.368 537.010 92.116 1.00 25.67 ? 537 PRO A O 1 ATOM 3475 C CB . PRO A 1 483 ? 122.806 540.138 93.004 1.00 22.08 ? 537 PRO A CB 1 ATOM 3476 C CG . PRO A 1 483 ? 122.090 540.845 94.084 1.00 25.12 ? 537 PRO A CG 1 ATOM 3477 C CD . PRO A 1 483 ? 120.727 541.122 93.544 1.00 21.08 ? 537 PRO A CD 1 ATOM 3478 N N . ARG A 1 484 ? 121.039 537.523 93.865 1.00 24.97 ? 538 ARG A N 1 ATOM 3479 C CA . ARG A 1 484 ? 121.001 536.145 94.379 1.00 24.92 ? 538 ARG A CA 1 ATOM 3480 C C . ARG A 1 484 ? 120.183 535.251 93.473 1.00 25.99 ? 538 ARG A C 1 ATOM 3481 O O . ARG A 1 484 ? 120.535 534.092 93.273 1.00 26.04 ? 538 ARG A O 1 ATOM 3482 C CB . ARG A 1 484 ? 120.538 536.095 95.838 1.00 28.68 ? 538 ARG A CB 1 ATOM 3483 C CG . ARG A 1 484 ? 120.165 534.675 96.329 1.00 52.13 ? 538 ARG A CG 1 ATOM 3484 C CD . ARG A 1 484 ? 121.334 533.651 96.308 1.00 62.88 ? 538 ARG A CD 1 ATOM 3485 N NE . ARG A 1 484 ? 120.867 532.257 96.313 1.00 57.09 ? 538 ARG A NE 1 ATOM 3486 C CZ . ARG A 1 484 ? 121.610 531.209 95.961 1.00 74.89 ? 538 ARG A CZ 1 ATOM 3487 N NH1 . ARG A 1 484 ? 122.868 531.376 95.575 1.00 59.34 ? 538 ARG A NH1 1 ATOM 3488 N NH2 . ARG A 1 484 ? 121.100 529.985 95.992 1.00 70.86 ? 538 ARG A NH2 1 ATOM 3489 N N . MET A 1 485 ? 119.114 535.792 92.897 1.00 22.34 ? 539 MET A N 1 ATOM 3490 C CA A MET A 1 485 ? 118.274 535.061 91.938 0.50 20.39 ? 539 MET A CA 1 ATOM 3491 C CA B MET A 1 485 ? 118.270 535.061 91.958 0.50 21.25 ? 539 MET A CA 1 ATOM 3492 C C . MET A 1 485 ? 119.109 534.748 90.698 1.00 24.68 ? 539 MET A C 1 ATOM 3493 O O . MET A 1 485 ? 119.068 533.633 90.212 1.00 24.78 ? 539 MET A O 1 ATOM 3494 C CB A MET A 1 485 ? 117.016 535.873 91.559 0.50 21.65 ? 539 MET A CB 1 ATOM 3495 C CB B MET A 1 485 ? 117.024 535.902 91.641 0.50 23.17 ? 539 MET A CB 1 ATOM 3496 C CG A MET A 1 485 ? 116.211 535.264 90.390 0.50 23.23 ? 539 MET A CG 1 ATOM 3497 C CG B MET A 1 485 ? 115.869 535.103 91.089 0.50 25.86 ? 539 MET A CG 1 ATOM 3498 S SD A MET A 1 485 ? 115.585 533.628 90.815 0.50 24.96 ? 539 MET A SD 1 ATOM 3499 S SD B MET A 1 485 ? 116.040 534.809 89.326 0.50 28.47 ? 539 MET A SD 1 ATOM 3500 C CE A MET A 1 485 ? 116.095 532.664 89.380 0.50 21.10 ? 539 MET A CE 1 ATOM 3501 C CE B MET A 1 485 ? 116.064 532.966 89.320 0.50 24.86 ? 539 MET A CE 1 ATOM 3502 N N . ARG A 1 486 ? 119.907 535.716 90.202 1.00 21.86 ? 540 ARG A N 1 ATOM 3503 C CA . ARG A 1 486 ? 120.777 535.476 89.039 1.00 21.84 ? 540 ARG A CA 1 ATOM 3504 C C . ARG A 1 486 ? 121.834 534.397 89.314 1.00 21.84 ? 540 ARG A C 1 ATOM 3505 O O . ARG A 1 486 ? 122.089 533.583 88.434 1.00 19.11 ? 540 ARG A O 1 ATOM 3506 C CB . ARG A 1 486 ? 121.463 536.755 88.564 1.00 23.74 ? 540 ARG A CB 1 ATOM 3507 C CG . ARG A 1 486 ? 120.475 537.806 88.110 1.00 34.28 ? 540 ARG A CG 1 ATOM 3508 C CD . ARG A 1 486 ? 121.173 538.882 87.298 1.00 40.08 ? 540 ARG A CD 1 ATOM 3509 N NE . ARG A 1 486 ? 122.200 539.631 88.040 1.00 36.25 ? 540 ARG A NE 1 ATOM 3510 C CZ . ARG A 1 486 ? 121.957 540.637 88.882 1.00 40.71 ? 540 ARG A CZ 1 ATOM 3511 N NH1 . ARG A 1 486 ? 120.713 541.032 89.118 1.00 28.68 ? 540 ARG A NH1 1 ATOM 3512 N NH2 . ARG A 1 486 ? 122.956 541.255 89.491 1.00 25.65 ? 540 ARG A NH2 1 ATOM 3513 N N . ALA A 1 487 ? 122.409 534.371 90.551 1.00 17.53 ? 541 ALA A N 1 ATOM 3514 C CA . ALA A 1 487 ? 123.365 533.345 90.977 1.00 16.37 ? 541 ALA A CA 1 ATOM 3515 C C . ALA A 1 487 ? 122.684 531.960 91.012 1.00 25.81 ? 541 ALA A C 1 ATOM 3516 O O . ALA A 1 487 ? 123.270 530.985 90.545 1.00 25.08 ? 541 ALA A O 1 ATOM 3517 C CB . ALA A 1 487 ? 123.963 533.687 92.329 1.00 15.52 ? 541 ALA A CB 1 ATOM 3518 N N . TRP A 1 488 ? 121.446 531.894 91.532 1.00 26.46 ? 542 TRP A N 1 ATOM 3519 C CA . TRP A 1 488 ? 120.657 530.677 91.595 1.00 28.53 ? 542 TRP A CA 1 ATOM 3520 C C . TRP A 1 488 ? 120.403 530.165 90.189 1.00 34.04 ? 542 TRP A C 1 ATOM 3521 O O . TRP A 1 488 ? 120.564 528.959 89.927 1.00 35.55 ? 542 TRP A O 1 ATOM 3522 C CB . TRP A 1 488 ? 119.320 530.915 92.332 1.00 28.15 ? 542 TRP A CB 1 ATOM 3523 C CG . TRP A 1 488 ? 118.556 529.639 92.544 1.00 29.94 ? 542 TRP A CG 1 ATOM 3524 C CD1 . TRP A 1 488 ? 118.559 528.861 93.667 1.00 33.13 ? 542 TRP A CD1 1 ATOM 3525 C CD2 . TRP A 1 488 ? 117.763 528.936 91.571 1.00 29.95 ? 542 TRP A CD2 1 ATOM 3526 N NE1 . TRP A 1 488 ? 117.753 527.758 93.481 1.00 32.86 ? 542 TRP A NE1 1 ATOM 3527 C CE2 . TRP A 1 488 ? 117.278 527.763 92.193 1.00 33.88 ? 542 TRP A CE2 1 ATOM 3528 C CE3 . TRP A 1 488 ? 117.363 529.216 90.246 1.00 31.34 ? 542 TRP A CE3 1 ATOM 3529 C CZ2 . TRP A 1 488 ? 116.446 526.853 91.529 1.00 32.77 ? 542 TRP A CZ2 1 ATOM 3530 C CZ3 . TRP A 1 488 ? 116.574 528.294 89.577 1.00 32.34 ? 542 TRP A CZ3 1 ATOM 3531 C CH2 . TRP A 1 488 ? 116.102 527.142 90.225 1.00 32.88 ? 542 TRP A CH2 1 ATOM 3532 N N . TRP A 1 489 ? 119.984 531.070 89.289 1.00 28.53 ? 543 TRP A N 1 ATOM 3533 C CA . TRP A 1 489 ? 119.720 530.733 87.889 1.00 26.84 ? 543 TRP A CA 1 ATOM 3534 C C . TRP A 1 489 ? 120.991 530.198 87.226 1.00 29.41 ? 543 TRP A C 1 ATOM 3535 O O . TRP A 1 489 ? 120.936 529.135 86.623 1.00 29.90 ? 543 TRP A O 1 ATOM 3536 C CB . TRP A 1 489 ? 119.182 531.944 87.174 1.00 25.41 ? 543 TRP A CB 1 ATOM 3537 C CG . TRP A 1 489 ? 118.724 531.705 85.777 1.00 26.77 ? 543 TRP A CG 1 ATOM 3538 C CD1 . TRP A 1 489 ? 119.422 531.969 84.645 1.00 29.70 ? 543 TRP A CD1 1 ATOM 3539 C CD2 . TRP A 1 489 ? 117.421 531.286 85.354 1.00 26.77 ? 543 TRP A CD2 1 ATOM 3540 N NE1 . TRP A 1 489 ? 118.638 531.750 83.539 1.00 29.01 ? 543 TRP A NE1 1 ATOM 3541 C CE2 . TRP A 1 489 ? 117.406 531.330 83.940 1.00 30.22 ? 543 TRP A CE2 1 ATOM 3542 C CE3 . TRP A 1 489 ? 116.255 530.883 86.033 1.00 28.23 ? 543 TRP A CE3 1 ATOM 3543 C CZ2 . TRP A 1 489 ? 116.276 531.002 83.186 1.00 29.56 ? 543 TRP A CZ2 1 ATOM 3544 C CZ3 . TRP A 1 489 ? 115.130 530.552 85.282 1.00 29.93 ? 543 TRP A CZ3 1 ATOM 3545 C CH2 . TRP A 1 489 ? 115.155 530.594 83.874 1.00 30.60 ? 543 TRP A CH2 1 ATOM 3546 N N . SER A 1 490 ? 122.130 530.892 87.400 1.00 23.64 ? 544 SER A N 1 ATOM 3547 C CA A SER A 1 490 ? 123.419 530.476 86.850 0.50 23.20 ? 544 SER A CA 1 ATOM 3548 C CA B SER A 1 490 ? 123.418 530.490 86.864 0.50 23.12 ? 544 SER A CA 1 ATOM 3549 C C . SER A 1 490 ? 123.772 529.066 87.327 1.00 28.14 ? 544 SER A C 1 ATOM 3550 O O . SER A 1 490 ? 124.151 528.206 86.526 1.00 27.55 ? 544 SER A O 1 ATOM 3551 C CB A SER A 1 490 ? 124.517 531.463 87.235 0.50 25.55 ? 544 SER A CB 1 ATOM 3552 C CB B SER A 1 490 ? 124.478 531.486 87.309 0.50 25.23 ? 544 SER A CB 1 ATOM 3553 O OG A SER A 1 490 ? 124.226 532.779 86.794 0.50 32.72 ? 544 SER A OG 1 ATOM 3554 O OG B SER A 1 490 ? 125.732 531.181 86.738 0.50 31.12 ? 544 SER A OG 1 ATOM 3555 N N . ASN A 1 491 ? 123.616 528.817 88.624 1.00 25.53 ? 545 ASN A N 1 ATOM 3556 C CA . ASN A 1 491 ? 123.895 527.528 89.224 1.00 24.76 ? 545 ASN A CA 1 ATOM 3557 C C . ASN A 1 491 ? 122.978 526.410 88.680 1.00 29.15 ? 545 ASN A C 1 ATOM 3558 O O . ASN A 1 491 ? 123.411 525.273 88.608 1.00 31.17 ? 545 ASN A O 1 ATOM 3559 C CB . ASN A 1 491 ? 123.823 527.676 90.737 1.00 24.40 ? 545 ASN A CB 1 ATOM 3560 C CG . ASN A 1 491 ? 124.291 526.459 91.479 1.00 54.93 ? 545 ASN A CG 1 ATOM 3561 O OD1 . ASN A 1 491 ? 123.513 525.840 92.209 1.00 67.42 ? 545 ASN A OD1 1 ATOM 3562 N ND2 . ASN A 1 491 ? 125.542 526.038 91.264 1.00 31.80 ? 545 ASN A ND2 1 ATOM 3563 N N . MET A 1 492 ? 121.740 526.726 88.247 1.00 25.85 ? 546 MET A N 1 ATOM 3564 C CA . MET A 1 492 ? 120.799 525.748 87.654 1.00 25.51 ? 546 MET A CA 1 ATOM 3565 C C . MET A 1 492 ? 121.313 525.122 86.340 1.00 29.36 ? 546 MET A C 1 ATOM 3566 O O . MET A 1 492 ? 120.884 524.034 85.965 1.00 30.30 ? 546 MET A O 1 ATOM 3567 C CB . MET A 1 492 ? 119.422 526.399 87.449 1.00 27.79 ? 546 MET A CB 1 ATOM 3568 C CG . MET A 1 492 ? 118.319 525.446 87.151 1.00 31.63 ? 546 MET A CG 1 ATOM 3569 S SD . MET A 1 492 ? 118.027 524.231 88.428 1.00 35.73 ? 546 MET A SD 1 ATOM 3570 C CE . MET A 1 492 ? 117.321 522.937 87.392 1.00 31.55 ? 546 MET A CE 1 ATOM 3571 N N . PHE A 1 493 ? 122.242 525.801 85.661 1.00 25.60 ? 547 PHE A N 1 ATOM 3572 C CA . PHE A 1 493 ? 122.858 525.318 84.424 1.00 24.33 ? 547 PHE A CA 1 ATOM 3573 C C . PHE A 1 493 ? 124.012 524.344 84.633 1.00 28.36 ? 547 PHE A C 1 ATOM 3574 O O . PHE A 1 493 ? 124.518 523.811 83.646 1.00 28.04 ? 547 PHE A O 1 ATOM 3575 C CB . PHE A 1 493 ? 123.269 526.480 83.516 1.00 24.91 ? 547 PHE A CB 1 ATOM 3576 C CG . PHE A 1 493 ? 122.065 527.162 82.902 1.00 25.03 ? 547 PHE A CG 1 ATOM 3577 C CD1 . PHE A 1 493 ? 121.497 526.679 81.727 1.00 25.65 ? 547 PHE A CD1 1 ATOM 3578 C CD2 . PHE A 1 493 ? 121.457 528.243 83.538 1.00 25.16 ? 547 PHE A CD2 1 ATOM 3579 C CE1 . PHE A 1 493 ? 120.357 527.277 81.189 1.00 25.48 ? 547 PHE A CE1 1 ATOM 3580 C CE2 . PHE A 1 493 ? 120.328 528.848 82.989 1.00 26.83 ? 547 PHE A CE2 1 ATOM 3581 C CZ . PHE A 1 493 ? 119.800 528.379 81.803 1.00 24.28 ? 547 PHE A CZ 1 ATOM 3582 N N . SER A 1 494 ? 124.362 524.012 85.893 1.00 25.84 ? 548 SER A N 1 ATOM 3583 C CA . SER A 1 494 ? 125.399 523.001 86.131 1.00 25.78 ? 548 SER A CA 1 ATOM 3584 C C . SER A 1 494 ? 124.884 521.684 85.576 1.00 29.98 ? 548 SER A C 1 ATOM 3585 O O . SER A 1 494 ? 123.651 521.445 85.545 1.00 28.03 ? 548 SER A O 1 ATOM 3586 C CB . SER A 1 494 ? 125.706 522.847 87.618 1.00 29.90 ? 548 SER A CB 1 ATOM 3587 O OG . SER A 1 494 ? 124.689 522.084 88.244 1.00 39.67 ? 548 SER A OG 1 ATOM 3588 N N . PHE A 1 495 ? 125.820 520.828 85.116 1.00 26.97 ? 549 PHE A N 1 ATOM 3589 C CA . PHE A 1 495 ? 125.403 519.558 84.524 1.00 26.18 ? 549 PHE A CA 1 ATOM 3590 C C . PHE A 1 495 ? 124.674 518.687 85.506 1.00 28.34 ? 549 PHE A C 1 ATOM 3591 O O . PHE A 1 495 ? 123.805 517.949 85.099 1.00 26.61 ? 549 PHE A O 1 ATOM 3592 C CB . PHE A 1 495 ? 126.555 518.831 83.834 1.00 27.37 ? 549 PHE A CB 1 ATOM 3593 C CG . PHE A 1 495 ? 127.174 519.657 82.728 1.00 28.25 ? 549 PHE A CG 1 ATOM 3594 C CD1 . PHE A 1 495 ? 126.440 520.008 81.600 1.00 30.64 ? 549 PHE A CD1 1 ATOM 3595 C CD2 . PHE A 1 495 ? 128.497 520.062 82.804 1.00 30.24 ? 549 PHE A CD2 1 ATOM 3596 C CE1 . PHE A 1 495 ? 127.025 520.760 80.578 1.00 31.49 ? 549 PHE A CE1 1 ATOM 3597 C CE2 . PHE A 1 495 ? 129.077 520.821 81.786 1.00 32.30 ? 549 PHE A CE2 1 ATOM 3598 C CZ . PHE A 1 495 ? 128.346 521.153 80.673 1.00 30.29 ? 549 PHE A CZ 1 ATOM 3599 N N . ASP A 1 496 ? 124.956 518.844 86.800 1.00 28.02 ? 550 ASP A N 1 ATOM 3600 C CA . ASP A 1 496 ? 124.266 518.146 87.876 1.00 29.29 ? 550 ASP A CA 1 ATOM 3601 C C . ASP A 1 496 ? 122.833 518.641 88.056 1.00 32.16 ? 550 ASP A C 1 ATOM 3602 O O . ASP A 1 496 ? 121.954 517.834 88.317 1.00 31.93 ? 550 ASP A O 1 ATOM 3603 C CB . ASP A 1 496 ? 125.066 518.279 89.192 1.00 32.55 ? 550 ASP A CB 1 ATOM 3604 C CG . ASP A 1 496 ? 126.349 517.453 89.212 1.00 58.13 ? 550 ASP A CG 1 ATOM 3605 O OD1 . ASP A 1 496 ? 126.466 516.497 88.389 1.00 60.73 ? 550 ASP A OD1 1 ATOM 3606 O OD2 . ASP A 1 496 ? 127.230 517.744 90.056 1.00 67.92 ? 550 ASP A OD2 1 ATOM 3607 N N . ASN A 1 497 ? 122.596 519.954 87.940 1.00 28.68 ? 551 ASN A N 1 ATOM 3608 C CA . ASN A 1 497 ? 121.276 520.521 88.147 1.00 28.34 ? 551 ASN A CA 1 ATOM 3609 C C . ASN A 1 497 ? 120.408 520.441 86.932 1.00 33.60 ? 551 ASN A C 1 ATOM 3610 O O . ASN A 1 497 ? 119.226 520.144 87.056 1.00 34.75 ? 551 ASN A O 1 ATOM 3611 C CB . ASN A 1 497 ? 121.363 521.939 88.676 1.00 28.28 ? 551 ASN A CB 1 ATOM 3612 C CG . ASN A 1 497 ? 121.829 521.991 90.100 1.00 46.20 ? 551 ASN A CG 1 ATOM 3613 O OD1 . ASN A 1 497 ? 121.641 521.047 90.874 1.00 44.53 ? 551 ASN A OD1 1 ATOM 3614 N ND2 . ASN A 1 497 ? 122.451 523.092 90.478 1.00 36.85 ? 551 ASN A ND2 1 ATOM 3615 N N . TYR A 1 498 ? 120.974 520.695 85.755 1.00 29.51 ? 552 TYR A N 1 ATOM 3616 C CA . TYR A 1 498 ? 120.219 520.615 84.512 1.00 27.77 ? 552 TYR A CA 1 ATOM 3617 C C . TYR A 1 498 ? 120.443 519.229 83.910 1.00 32.52 ? 552 TYR A C 1 ATOM 3618 O O . TYR A 1 498 ? 121.279 519.042 83.033 1.00 31.93 ? 552 TYR A O 1 ATOM 3619 C CB . TYR A 1 498 ? 120.659 521.743 83.580 1.00 26.65 ? 552 TYR A CB 1 ATOM 3620 C CG . TYR A 1 498 ? 119.872 521.917 82.299 1.00 25.07 ? 552 TYR A CG 1 ATOM 3621 C CD1 . TYR A 1 498 ? 118.756 521.118 82.015 1.00 26.19 ? 552 TYR A CD1 1 ATOM 3622 C CD2 . TYR A 1 498 ? 120.221 522.896 81.378 1.00 25.09 ? 552 TYR A CD2 1 ATOM 3623 C CE1 . TYR A 1 498 ? 118.045 521.266 80.819 1.00 24.04 ? 552 TYR A CE1 1 ATOM 3624 C CE2 . TYR A 1 498 ? 119.504 523.066 80.192 1.00 25.49 ? 552 TYR A CE2 1 ATOM 3625 C CZ . TYR A 1 498 ? 118.406 522.266 79.929 1.00 31.69 ? 552 TYR A CZ 1 ATOM 3626 O OH . TYR A 1 498 ? 117.721 522.456 78.758 1.00 37.29 ? 552 TYR A OH 1 ATOM 3627 N N . GLU A 1 499 ? 119.699 518.253 84.417 1.00 30.48 ? 553 GLU A N 1 ATOM 3628 C CA . GLU A 1 499 ? 119.810 516.871 83.981 1.00 30.41 ? 553 GLU A CA 1 ATOM 3629 C C . GLU A 1 499 ? 119.481 516.724 82.494 1.00 34.47 ? 553 GLU A C 1 ATOM 3630 O O . GLU A 1 499 ? 118.532 517.336 81.983 1.00 34.12 ? 553 GLU A O 1 ATOM 3631 C CB . GLU A 1 499 ? 118.994 515.939 84.875 1.00 31.45 ? 553 GLU A CB 1 ATOM 3632 C CG . GLU A 1 499 ? 119.583 515.887 86.278 1.00 50.11 ? 553 GLU A CG 1 ATOM 3633 C CD . GLU A 1 499 ? 118.944 514.983 87.316 1.00 83.33 ? 553 GLU A CD 1 ATOM 3634 O OE1 . GLU A 1 499 ? 119.471 514.948 88.453 1.00 59.45 ? 553 GLU A OE1 1 ATOM 3635 O OE2 . GLU A 1 499 ? 117.919 514.330 87.010 1.00 89.34 ? 553 GLU A OE2 1 ATOM 3636 N N . GLY A 1 500 ? 120.354 516.009 81.801 1.00 30.10 ? 554 GLY A N 1 ATOM 3637 C CA . GLY A 1 500 ? 120.226 515.795 80.371 1.00 29.93 ? 554 GLY A CA 1 ATOM 3638 C C . GLY A 1 500 ? 121.006 516.787 79.527 1.00 33.35 ? 554 GLY A C 1 ATOM 3639 O O . GLY A 1 500 ? 121.018 516.658 78.303 1.00 35.11 ? 554 GLY A O 1 ATOM 3640 N N . SER A 1 501 ? 121.629 517.806 80.146 1.00 26.36 ? 555 SER A N 1 ATOM 3641 C CA . SER A 1 501 ? 122.424 518.789 79.412 1.00 23.61 ? 555 SER A CA 1 ATOM 3642 C C . SER A 1 501 ? 123.864 518.306 79.316 1.00 25.99 ? 555 SER A C 1 ATOM 3643 O O . SER A 1 501 ? 124.321 517.488 80.121 1.00 24.04 ? 555 SER A O 1 ATOM 3644 C CB . SER A 1 501 ? 122.346 520.178 80.043 1.00 22.39 ? 555 SER A CB 1 ATOM 3645 O OG . SER A 1 501 ? 122.994 520.249 81.302 1.00 30.41 ? 555 SER A OG 1 ATOM 3646 N N . ALA A 1 502 ? 124.563 518.804 78.303 1.00 23.23 ? 556 ALA A N 1 ATOM 3647 C CA . ALA A 1 502 ? 125.932 518.462 78.009 1.00 22.22 ? 556 ALA A CA 1 ATOM 3648 C C . ALA A 1 502 ? 126.634 519.686 77.435 1.00 26.33 ? 556 ALA A C 1 ATOM 3649 O O . ALA A 1 502 ? 125.972 520.694 77.151 1.00 26.09 ? 556 ALA A O 1 ATOM 3650 C CB . ALA A 1 502 ? 125.968 517.303 77.033 1.00 22.17 ? 556 ALA A CB 1 ATOM 3651 N N . PRO A 1 503 ? 127.984 519.641 77.319 1.00 22.75 ? 557 PRO A N 1 ATOM 3652 C CA . PRO A 1 503 ? 128.726 520.809 76.828 1.00 21.75 ? 557 PRO A CA 1 ATOM 3653 C C . PRO A 1 503 ? 128.310 521.305 75.443 1.00 25.36 ? 557 PRO A C 1 ATOM 3654 O O . PRO A 1 503 ? 128.592 522.485 75.130 1.00 25.86 ? 557 PRO A O 1 ATOM 3655 C CB . PRO A 1 503 ? 130.187 520.325 76.855 1.00 22.63 ? 557 PRO A CB 1 ATOM 3656 C CG . PRO A 1 503 ? 130.208 519.345 77.940 1.00 26.64 ? 557 PRO A CG 1 ATOM 3657 C CD . PRO A 1 503 ? 128.919 518.598 77.790 1.00 22.86 ? 557 PRO A CD 1 ATOM 3658 N N . ASN A 1 504 ? 127.636 520.450 74.627 1.00 18.92 ? 558 ASN A N 1 ATOM 3659 C CA . ASN A 1 504 ? 127.205 520.895 73.301 1.00 20.63 ? 558 ASN A CA 1 ATOM 3660 C C . ASN A 1 504 ? 125.748 521.361 73.263 1.00 26.43 ? 558 ASN A C 1 ATOM 3661 O O . ASN A 1 504 ? 125.179 521.513 72.165 1.00 26.85 ? 558 ASN A O 1 ATOM 3662 C CB . ASN A 1 504 ? 127.512 519.870 72.205 1.00 26.60 ? 558 ASN A CB 1 ATOM 3663 C CG . ASN A 1 504 ? 126.794 518.568 72.334 1.00 40.97 ? 558 ASN A CG 1 ATOM 3664 O OD1 . ASN A 1 504 ? 126.590 518.063 73.442 1.00 26.40 ? 558 ASN A OD1 1 ATOM 3665 N ND2 . ASN A 1 504 ? 126.423 517.985 71.191 1.00 32.96 ? 558 ASN A ND2 1 ATOM 3666 N N . LEU A 1 505 ? 125.159 521.597 74.459 1.00 22.62 ? 559 LEU A N 1 ATOM 3667 C CA A LEU A 1 505 ? 123.803 522.126 74.598 0.50 23.24 ? 559 LEU A CA 1 ATOM 3668 C CA B LEU A 1 505 ? 123.814 522.128 74.591 0.50 22.36 ? 559 LEU A CA 1 ATOM 3669 C C . LEU A 1 505 ? 123.930 523.598 74.996 1.00 27.20 ? 559 LEU A C 1 ATOM 3670 O O . LEU A 1 505 ? 124.530 523.906 76.025 1.00 26.27 ? 559 LEU A O 1 ATOM 3671 C CB A LEU A 1 505 ? 122.980 521.348 75.662 0.50 23.66 ? 559 LEU A CB 1 ATOM 3672 C CB B LEU A 1 505 ? 122.966 521.328 75.620 0.50 22.05 ? 559 LEU A CB 1 ATOM 3673 C CG A LEU A 1 505 ? 121.453 521.615 75.715 0.50 28.43 ? 559 LEU A CG 1 ATOM 3674 C CG B LEU A 1 505 ? 121.524 521.828 75.859 0.50 25.14 ? 559 LEU A CG 1 ATOM 3675 C CD1 A LEU A 1 505 ? 120.727 520.429 76.232 0.50 28.59 ? 559 LEU A CD1 1 ATOM 3676 C CD1 B LEU A 1 505 ? 120.735 521.830 74.602 0.50 24.25 ? 559 LEU A CD1 1 ATOM 3677 C CD2 A LEU A 1 505 ? 121.108 522.777 76.637 0.50 30.69 ? 559 LEU A CD2 1 ATOM 3678 C CD2 B LEU A 1 505 ? 120.806 520.992 76.861 0.50 24.62 ? 559 LEU A CD2 1 ATOM 3679 N N . TYR A 1 506 ? 123.363 524.495 74.184 1.00 24.30 ? 560 TYR A N 1 ATOM 3680 C CA . TYR A 1 506 ? 123.354 525.932 74.442 1.00 22.96 ? 560 TYR A CA 1 ATOM 3681 C C . TYR A 1 506 ? 121.913 526.408 74.631 1.00 27.24 ? 560 TYR A C 1 ATOM 3682 O O . TYR A 1 506 ? 121.001 525.575 74.651 1.00 28.31 ? 560 TYR A O 1 ATOM 3683 C CB . TYR A 1 506 ? 124.164 526.698 73.403 1.00 22.76 ? 560 TYR A CB 1 ATOM 3684 C CG . TYR A 1 506 ? 125.615 526.269 73.410 1.00 23.91 ? 560 TYR A CG 1 ATOM 3685 C CD1 . TYR A 1 506 ? 126.031 525.148 72.706 1.00 25.29 ? 560 TYR A CD1 1 ATOM 3686 C CD2 . TYR A 1 506 ? 126.563 526.959 74.160 1.00 24.37 ? 560 TYR A CD2 1 ATOM 3687 C CE1 . TYR A 1 506 ? 127.351 524.718 72.751 1.00 25.52 ? 560 TYR A CE1 1 ATOM 3688 C CE2 . TYR A 1 506 ? 127.891 526.554 74.187 1.00 25.13 ? 560 TYR A CE2 1 ATOM 3689 C CZ . TYR A 1 506 ? 128.285 525.441 73.467 1.00 31.77 ? 560 TYR A CZ 1 ATOM 3690 O OH . TYR A 1 506 ? 129.604 525.049 73.448 1.00 37.43 ? 560 TYR A OH 1 ATOM 3691 N N . VAL A 1 507 ? 121.688 527.713 74.857 1.00 22.40 ? 561 VAL A N 1 ATOM 3692 C CA . VAL A 1 507 ? 120.392 528.159 75.349 1.00 21.01 ? 561 VAL A CA 1 ATOM 3693 C C . VAL A 1 507 ? 119.785 529.349 74.639 1.00 23.25 ? 561 VAL A C 1 ATOM 3694 O O . VAL A 1 507 ? 120.469 530.277 74.189 1.00 21.52 ? 561 VAL A O 1 ATOM 3695 C CB . VAL A 1 507 ? 120.510 528.438 76.906 1.00 24.49 ? 561 VAL A CB 1 ATOM 3696 C CG1 . VAL A 1 507 ? 119.189 528.888 77.539 1.00 23.06 ? 561 VAL A CG1 1 ATOM 3697 C CG2 . VAL A 1 507 ? 121.065 527.220 77.652 1.00 24.27 ? 561 VAL A CG2 1 ATOM 3698 N N . TRP A 1 508 ? 118.452 529.319 74.593 1.00 20.21 ? 562 TRP A N 1 ATOM 3699 C CA . TRP A 1 508 ? 117.673 530.387 74.018 1.00 20.62 ? 562 TRP A CA 1 ATOM 3700 C C . TRP A 1 508 ? 116.726 530.907 75.091 1.00 24.30 ? 562 TRP A C 1 ATOM 3701 O O . TRP A 1 508 ? 115.937 530.142 75.648 1.00 23.87 ? 562 TRP A O 1 ATOM 3702 C CB . TRP A 1 508 ? 116.934 529.826 72.798 1.00 19.26 ? 562 TRP A CB 1 ATOM 3703 C CG . TRP A 1 508 ? 115.866 530.662 72.160 1.00 19.30 ? 562 TRP A CG 1 ATOM 3704 C CD1 . TRP A 1 508 ? 115.730 532.021 72.186 1.00 21.82 ? 562 TRP A CD1 1 ATOM 3705 C CD2 . TRP A 1 508 ? 114.824 530.174 71.321 1.00 18.93 ? 562 TRP A CD2 1 ATOM 3706 N NE1 . TRP A 1 508 ? 114.655 532.402 71.428 1.00 19.81 ? 562 TRP A NE1 1 ATOM 3707 C CE2 . TRP A 1 508 ? 114.087 531.287 70.873 1.00 20.99 ? 562 TRP A CE2 1 ATOM 3708 C CE3 . TRP A 1 508 ? 114.437 528.893 70.898 1.00 19.92 ? 562 TRP A CE3 1 ATOM 3709 C CZ2 . TRP A 1 508 ? 112.984 531.156 70.041 1.00 20.16 ? 562 TRP A CZ2 1 ATOM 3710 C CZ3 . TRP A 1 508 ? 113.361 528.774 70.043 1.00 20.01 ? 562 TRP A CZ3 1 ATOM 3711 C CH2 . TRP A 1 508 ? 112.647 529.892 69.627 1.00 20.41 ? 562 TRP A CH2 1 ATOM 3712 N N . ASN A 1 509 ? 116.835 532.210 75.393 1.00 20.60 ? 563 ASN A N 1 ATOM 3713 C CA . ASN A 1 509 ? 115.955 532.942 76.301 1.00 20.24 ? 563 ASN A CA 1 ATOM 3714 C C . ASN A 1 509 ? 114.913 533.679 75.490 1.00 21.07 ? 563 ASN A C 1 ATOM 3715 O O . ASN A 1 509 ? 115.212 534.645 74.791 1.00 21.31 ? 563 ASN A O 1 ATOM 3716 C CB . ASN A 1 509 ? 116.713 533.959 77.176 1.00 24.24 ? 563 ASN A CB 1 ATOM 3717 C CG . ASN A 1 509 ? 117.672 533.379 78.193 1.00 34.63 ? 563 ASN A CG 1 ATOM 3718 O OD1 . ASN A 1 509 ? 118.669 534.017 78.515 1.00 22.88 ? 563 ASN A OD1 1 ATOM 3719 N ND2 . ASN A 1 509 ? 117.395 532.184 78.737 1.00 21.19 ? 563 ASN A ND2 1 ATOM 3720 N N . ASP A 1 510 ? 113.689 533.248 75.617 1.00 16.59 ? 564 ASP A N 1 ATOM 3721 C CA . ASP A 1 510 ? 112.559 533.840 74.921 1.00 16.76 ? 564 ASP A CA 1 ATOM 3722 C C . ASP A 1 510 ? 111.606 534.431 75.947 1.00 23.21 ? 564 ASP A C 1 ATOM 3723 O O . ASP A 1 510 ? 111.726 534.139 77.147 1.00 22.56 ? 564 ASP A O 1 ATOM 3724 C CB . ASP A 1 510 ? 111.853 532.751 74.083 1.00 18.12 ? 564 ASP A CB 1 ATOM 3725 C CG . ASP A 1 510 ? 110.656 533.216 73.290 1.00 23.21 ? 564 ASP A CG 1 ATOM 3726 O OD1 . ASP A 1 510 ? 110.654 534.387 72.850 1.00 24.29 ? 564 ASP A OD1 1 ATOM 3727 O OD2 . ASP A 1 510 ? 109.733 532.402 73.084 1.00 25.48 ? 564 ASP A OD2 1 ATOM 3728 N N . MET A 1 511 ? 110.684 535.295 75.490 1.00 19.48 ? 565 MET A N 1 ATOM 3729 C CA . MET A 1 511 ? 109.600 535.830 76.314 1.00 19.56 ? 565 MET A CA 1 ATOM 3730 C C . MET A 1 511 ? 110.113 536.514 77.599 1.00 21.02 ? 565 MET A C 1 ATOM 3731 O O . MET A 1 511 ? 109.454 536.520 78.647 1.00 17.78 ? 565 MET A O 1 ATOM 3732 C CB . MET A 1 511 ? 108.582 534.695 76.579 1.00 22.35 ? 565 MET A CB 1 ATOM 3733 C CG . MET A 1 511 ? 107.707 534.382 75.362 1.00 26.70 ? 565 MET A CG 1 ATOM 3734 S SD . MET A 1 511 ? 106.637 533.024 75.806 1.00 33.07 ? 565 MET A SD 1 ATOM 3735 C CE . MET A 1 511 ? 105.380 533.882 76.691 1.00 30.38 ? 565 MET A CE 1 ATOM 3736 N N . ASN A 1 512 ? 111.330 537.082 77.495 1.00 17.78 ? 566 ASN A N 1 ATOM 3737 C CA . ASN A 1 512 ? 111.998 537.714 78.627 1.00 17.40 ? 566 ASN A CA 1 ATOM 3738 C C . ASN A 1 512 ? 111.788 539.233 78.727 1.00 22.52 ? 566 ASN A C 1 ATOM 3739 O O . ASN A 1 512 ? 112.559 539.916 79.420 1.00 19.87 ? 566 ASN A O 1 ATOM 3740 C CB . ASN A 1 512 ? 113.472 537.355 78.675 1.00 14.54 ? 566 ASN A CB 1 ATOM 3741 C CG . ASN A 1 512 ? 114.270 537.694 77.463 1.00 28.74 ? 566 ASN A CG 1 ATOM 3742 O OD1 . ASN A 1 512 ? 113.783 537.703 76.322 1.00 20.59 ? 566 ASN A OD1 1 ATOM 3743 N ND2 . ASN A 1 512 ? 115.561 537.805 77.676 1.00 28.26 ? 566 ASN A ND2 1 ATOM 3744 N N . GLU A 1 513 ? 110.703 539.742 78.116 1.00 20.60 ? 567 GLU A N 1 ATOM 3745 C CA . GLU A 1 513 ? 110.345 541.164 78.233 1.00 21.10 ? 567 GLU A CA 1 ATOM 3746 C C . GLU A 1 513 ? 110.021 541.622 79.673 1.00 24.29 ? 567 GLU A C 1 ATOM 3747 O O . GLU A 1 513 ? 110.401 542.731 79.989 1.00 25.58 ? 567 GLU A O 1 ATOM 3748 C CB . GLU A 1 513 ? 109.180 541.545 77.290 1.00 22.56 ? 567 GLU A CB 1 ATOM 3749 C CG . GLU A 1 513 ? 109.517 541.395 75.810 1.00 30.78 ? 567 GLU A CG 1 ATOM 3750 C CD . GLU A 1 513 ? 109.692 539.965 75.332 1.00 33.90 ? 567 GLU A CD 1 ATOM 3751 O OE1 . GLU A 1 513 ? 109.045 539.058 75.902 1.00 35.85 ? 567 GLU A OE1 1 ATOM 3752 O OE2 . GLU A 1 513 ? 110.482 539.746 74.390 1.00 30.11 ? 567 GLU A OE2 1 ATOM 3753 N N . PRO A 1 514 ? 109.301 540.890 80.556 1.00 20.45 ? 568 PRO A N 1 ATOM 3754 C CA . PRO A 1 514 ? 108.722 539.535 80.406 1.00 19.91 ? 568 PRO A CA 1 ATOM 3755 C C . PRO A 1 514 ? 107.375 539.554 79.711 1.00 22.10 ? 568 PRO A C 1 ATOM 3756 O O . PRO A 1 514 ? 106.584 540.481 79.878 1.00 19.82 ? 568 PRO A O 1 ATOM 3757 C CB . PRO A 1 514 ? 108.571 539.078 81.869 1.00 21.43 ? 568 PRO A CB 1 ATOM 3758 C CG . PRO A 1 514 ? 108.180 540.380 82.586 1.00 24.55 ? 568 PRO A CG 1 ATOM 3759 C CD . PRO A 1 514 ? 109.006 541.453 81.900 1.00 20.59 ? 568 PRO A CD 1 ATOM 3760 N N . SER A 1 515 ? 107.108 538.507 78.967 1.00 20.85 ? 569 SER A N 1 ATOM 3761 C CA . SER A 1 515 ? 105.839 538.305 78.282 1.00 20.61 ? 569 SER A CA 1 ATOM 3762 C C . SER A 1 515 ? 104.934 537.584 79.294 1.00 25.73 ? 569 SER A C 1 ATOM 3763 O O . SER A 1 515 ? 105.303 536.524 79.795 1.00 24.98 ? 569 SER A O 1 ATOM 3764 C CB . SER A 1 515 ? 106.050 537.465 77.023 1.00 21.46 ? 569 SER A CB 1 ATOM 3765 O OG . SER A 1 515 ? 104.812 537.226 76.376 1.00 21.54 ? 569 SER A OG 1 ATOM 3766 N N . VAL A 1 516 ? 103.802 538.211 79.654 1.00 22.97 ? 570 VAL A N 1 ATOM 3767 C CA . VAL A 1 516 ? 102.817 537.738 80.640 1.00 23.15 ? 570 VAL A CA 1 ATOM 3768 C C . VAL A 1 516 ? 101.466 537.718 79.898 1.00 31.56 ? 570 VAL A C 1 ATOM 3769 O O . VAL A 1 516 ? 100.927 538.791 79.647 1.00 31.99 ? 570 VAL A O 1 ATOM 3770 C CB . VAL A 1 516 ? 102.802 538.734 81.824 1.00 26.49 ? 570 VAL A CB 1 ATOM 3771 C CG1 . VAL A 1 516 ? 101.827 538.295 82.908 1.00 25.99 ? 570 VAL A CG1 1 ATOM 3772 C CG2 . VAL A 1 516 ? 104.196 538.952 82.401 1.00 26.35 ? 570 VAL A CG2 1 ATOM 3773 N N . PHE A 1 517 ? 100.947 536.532 79.484 1.00 31.96 ? 571 PHE A N 1 ATOM 3774 C CA . PHE A 1 517 ? 99.767 536.454 78.587 1.00 33.40 ? 571 PHE A CA 1 ATOM 3775 C C . PHE A 1 517 ? 98.522 537.221 79.045 1.00 36.50 ? 571 PHE A C 1 ATOM 3776 O O . PHE A 1 517 ? 97.869 537.864 78.216 1.00 36.57 ? 571 PHE A O 1 ATOM 3777 C CB . PHE A 1 517 ? 99.384 535.009 78.215 1.00 36.24 ? 571 PHE A CB 1 ATOM 3778 C CG . PHE A 1 517 ? 100.311 534.333 77.212 1.00 39.33 ? 571 PHE A CG 1 ATOM 3779 C CD1 . PHE A 1 517 ? 101.157 535.088 76.391 1.00 42.52 ? 571 PHE A CD1 1 ATOM 3780 C CD2 . PHE A 1 517 ? 100.353 532.939 77.104 1.00 41.89 ? 571 PHE A CD2 1 ATOM 3781 C CE1 . PHE A 1 517 ? 102.034 534.462 75.502 1.00 43.63 ? 571 PHE A CE1 1 ATOM 3782 C CE2 . PHE A 1 517 ? 101.237 532.312 76.224 1.00 44.72 ? 571 PHE A CE2 1 ATOM 3783 C CZ . PHE A 1 517 ? 102.061 533.077 75.416 1.00 43.38 ? 571 PHE A CZ 1 ATOM 3784 N N . ASN A 1 518 ? 98.233 537.202 80.347 1.00 31.89 ? 572 ASN A N 1 ATOM 3785 C CA . ASN A 1 518 ? 97.085 537.909 80.908 1.00 31.17 ? 572 ASN A CA 1 ATOM 3786 C C . ASN A 1 518 ? 97.405 539.361 81.371 1.00 33.41 ? 572 ASN A C 1 ATOM 3787 O O . ASN A 1 518 ? 96.514 539.979 81.969 1.00 33.98 ? 572 ASN A O 1 ATOM 3788 C CB . ASN A 1 518 ? 96.508 537.077 82.078 1.00 32.86 ? 572 ASN A CB 1 ATOM 3789 C CG . ASN A 1 518 ? 97.260 537.171 83.420 1.00 63.19 ? 572 ASN A CG 1 ATOM 3790 O OD1 . ASN A 1 518 ? 98.464 537.484 83.523 1.00 57.66 ? 572 ASN A OD1 1 ATOM 3791 N ND2 . ASN A 1 518 ? 96.533 536.940 84.501 1.00 55.81 ? 572 ASN A ND2 1 ATOM 3792 N N . GLY A 1 519 ? 98.633 539.864 81.120 1.00 25.41 ? 573 GLY A N 1 ATOM 3793 C CA . GLY A 1 519 ? 99.081 541.157 81.622 1.00 24.29 ? 573 GLY A CA 1 ATOM 3794 C C . GLY A 1 519 ? 98.778 542.328 80.737 1.00 27.26 ? 573 GLY A C 1 ATOM 3795 O O . GLY A 1 519 ? 98.443 542.120 79.573 1.00 27.69 ? 573 GLY A O 1 ATOM 3796 N N . PRO A 1 520 ? 98.903 543.569 81.295 1.00 23.97 ? 574 PRO A N 1 ATOM 3797 C CA . PRO A 1 520 ? 98.670 544.790 80.500 1.00 23.25 ? 574 PRO A CA 1 ATOM 3798 C C . PRO A 1 520 ? 99.749 544.855 79.450 1.00 27.47 ? 574 PRO A C 1 ATOM 3799 O O . PRO A 1 520 ? 100.928 544.761 79.800 1.00 29.26 ? 574 PRO A O 1 ATOM 3800 C CB . PRO A 1 520 ? 98.864 545.914 81.516 1.00 24.87 ? 574 PRO A CB 1 ATOM 3801 C CG . PRO A 1 520 ? 99.783 545.322 82.575 1.00 29.35 ? 574 PRO A CG 1 ATOM 3802 C CD . PRO A 1 520 ? 99.309 543.905 82.674 1.00 25.47 ? 574 PRO A CD 1 ATOM 3803 N N . GLU A 1 521 ? 99.355 544.918 78.175 1.00 21.60 ? 575 GLU A N 1 ATOM 3804 C CA . GLU A 1 521 ? 100.279 544.960 77.052 1.00 21.23 ? 575 GLU A CA 1 ATOM 3805 C C . GLU A 1 521 ? 101.103 543.697 76.976 1.00 28.14 ? 575 GLU A C 1 ATOM 3806 O O . GLU A 1 521 ? 102.199 543.683 76.395 1.00 29.38 ? 575 GLU A O 1 ATOM 3807 C CB . GLU A 1 521 ? 101.177 546.202 77.099 1.00 21.63 ? 575 GLU A CB 1 ATOM 3808 C CG . GLU A 1 521 ? 100.439 547.508 77.328 1.00 23.16 ? 575 GLU A CG 1 ATOM 3809 C CD . GLU A 1 521 ? 101.355 548.707 77.233 1.00 34.21 ? 575 GLU A CD 1 ATOM 3810 O OE1 . GLU A 1 521 ? 101.373 549.343 76.159 1.00 28.48 ? 575 GLU A OE1 1 ATOM 3811 O OE2 . GLU A 1 521 ? 102.123 548.956 78.191 1.00 30.44 ? 575 GLU A OE2 1 ATOM 3812 N N . VAL A 1 522 ? 100.550 542.610 77.524 1.00 24.22 ? 576 VAL A N 1 ATOM 3813 C CA . VAL A 1 522 ? 101.193 541.301 77.519 1.00 23.75 ? 576 VAL A CA 1 ATOM 3814 C C . VAL A 1 522 ? 102.481 541.328 78.355 1.00 26.11 ? 576 VAL A C 1 ATOM 3815 O O . VAL A 1 522 ? 103.405 540.569 78.094 1.00 26.97 ? 576 VAL A O 1 ATOM 3816 C CB . VAL A 1 522 ? 101.403 540.711 76.088 1.00 26.75 ? 576 VAL A CB 1 ATOM 3817 C CG1 . VAL A 1 522 ? 101.464 539.194 76.144 1.00 26.17 ? 576 VAL A CG1 1 ATOM 3818 C CG2 . VAL A 1 522 ? 100.306 541.163 75.120 1.00 26.70 ? 576 VAL A CG2 1 ATOM 3819 N N . THR A 1 523 ? 102.541 542.178 79.367 1.00 21.32 ? 577 THR A N 1 ATOM 3820 C CA . THR A 1 523 ? 103.702 542.201 80.242 1.00 21.94 ? 577 THR A CA 1 ATOM 3821 C C . THR A 1 523 ? 103.245 542.302 81.711 1.00 25.66 ? 577 THR A C 1 ATOM 3822 O O . THR A 1 523 ? 102.056 542.157 82.024 1.00 23.97 ? 577 THR A O 1 ATOM 3823 C CB . THR A 1 523 ? 104.767 543.243 79.795 1.00 29.33 ? 577 THR A CB 1 ATOM 3824 O OG1 . THR A 1 523 ? 105.959 543.025 80.527 1.00 26.00 ? 577 THR A OG1 1 ATOM 3825 C CG2 . THR A 1 523 ? 104.321 544.687 79.958 1.00 27.19 ? 577 THR A CG2 1 ATOM 3826 N N . MET A 1 524 ? 104.238 542.516 82.585 1.00 21.52 ? 578 MET A N 1 ATOM 3827 C CA A MET A 1 524 ? 104.110 542.626 84.032 0.50 20.85 ? 578 MET A CA 1 ATOM 3828 C CA B MET A 1 524 ? 104.072 542.614 84.030 0.50 20.33 ? 578 MET A CA 1 ATOM 3829 C C . MET A 1 524 ? 103.425 543.920 84.437 1.00 25.28 ? 578 MET A C 1 ATOM 3830 O O . MET A 1 524 ? 103.678 544.971 83.835 1.00 23.87 ? 578 MET A O 1 ATOM 3831 C CB A MET A 1 524 ? 105.525 542.584 84.628 0.50 22.85 ? 578 MET A CB 1 ATOM 3832 C CB B MET A 1 524 ? 105.446 542.481 84.696 0.50 21.95 ? 578 MET A CB 1 ATOM 3833 C CG A MET A 1 524 ? 105.576 542.526 86.139 0.50 25.96 ? 578 MET A CG 1 ATOM 3834 C CG B MET A 1 524 ? 105.395 542.289 86.197 0.50 24.40 ? 578 MET A CG 1 ATOM 3835 S SD A MET A 1 524 ? 105.177 540.885 86.720 0.50 29.33 ? 578 MET A SD 1 ATOM 3836 S SD B MET A 1 524 ? 107.020 541.852 86.815 0.50 27.11 ? 578 MET A SD 1 ATOM 3837 C CE A MET A 1 524 ? 106.726 540.095 86.530 0.50 26.08 ? 578 MET A CE 1 ATOM 3838 C CE B MET A 1 524 ? 106.966 540.108 86.567 0.50 23.94 ? 578 MET A CE 1 ATOM 3839 N N . LEU A 1 525 ? 102.604 543.861 85.485 1.00 24.42 ? 579 LEU A N 1 ATOM 3840 C CA . LEU A 1 525 ? 101.944 545.040 86.064 1.00 23.73 ? 579 LEU A CA 1 ATOM 3841 C C . LEU A 1 525 ? 103.031 546.019 86.464 1.00 24.60 ? 579 LEU A C 1 ATOM 3842 O O . LEU A 1 525 ? 104.057 545.579 87.000 1.00 26.30 ? 579 LEU A O 1 ATOM 3843 C CB . LEU A 1 525 ? 101.199 544.650 87.345 1.00 24.38 ? 579 LEU A CB 1 ATOM 3844 C CG . LEU A 1 525 ? 99.978 543.745 87.202 1.00 31.62 ? 579 LEU A CG 1 ATOM 3845 C CD1 . LEU A 1 525 ? 99.471 543.328 88.562 1.00 32.56 ? 579 LEU A CD1 1 ATOM 3846 C CD2 . LEU A 1 525 ? 98.854 544.451 86.405 1.00 35.65 ? 579 LEU A CD2 1 ATOM 3847 N N . LYS A 1 526 ? 102.789 547.336 86.301 1.00 16.56 ? 580 LYS A N 1 ATOM 3848 C CA . LYS A 1 526 ? 103.758 548.388 86.643 1.00 15.36 ? 580 LYS A CA 1 ATOM 3849 C C . LYS A 1 526 ? 104.112 548.412 88.112 1.00 23.42 ? 580 LYS A C 1 ATOM 3850 O O . LYS A 1 526 ? 105.208 548.846 88.477 1.00 22.85 ? 580 LYS A O 1 ATOM 3851 C CB . LYS A 1 526 ? 103.212 549.769 86.287 1.00 16.51 ? 580 LYS A CB 1 ATOM 3852 C CG . LYS A 1 526 ? 102.854 549.985 84.826 1.00 27.92 ? 580 LYS A CG 1 ATOM 3853 C CD . LYS A 1 526 ? 103.994 550.632 84.172 1.00 30.07 ? 580 LYS A CD 1 ATOM 3854 C CE . LYS A 1 526 ? 103.764 551.036 82.749 1.00 15.26 ? 580 LYS A CE 1 ATOM 3855 N NZ . LYS A 1 526 ? 105.054 551.462 82.188 1.00 18.57 ? 580 LYS A NZ 1 ATOM 3856 N N . ASP A 1 527 ? 103.143 548.024 88.964 1.00 23.58 ? 581 ASP A N 1 ATOM 3857 C CA . ASP A 1 527 ? 103.242 548.091 90.420 1.00 23.80 ? 581 ASP A CA 1 ATOM 3858 C C . ASP A 1 527 ? 103.658 546.797 91.069 1.00 27.85 ? 581 ASP A C 1 ATOM 3859 O O . ASP A 1 527 ? 103.625 546.709 92.297 1.00 28.21 ? 581 ASP A O 1 ATOM 3860 C CB . ASP A 1 527 ? 101.960 548.639 91.049 1.00 26.04 ? 581 ASP A CB 1 ATOM 3861 C CG . ASP A 1 527 ? 100.689 547.873 90.745 1.00 38.43 ? 581 ASP A CG 1 ATOM 3862 O OD1 . ASP A 1 527 ? 100.743 546.906 89.945 1.00 38.54 ? 581 ASP A OD1 1 ATOM 3863 O OD2 . ASP A 1 527 ? 99.632 548.263 91.270 1.00 49.43 ? 581 ASP A OD2 1 ATOM 3864 N N . ALA A 1 528 ? 104.180 545.834 90.267 1.00 22.74 ? 582 ALA A N 1 ATOM 3865 C CA . ALA A 1 528 ? 104.767 544.655 90.847 1.00 21.54 ? 582 ALA A CA 1 ATOM 3866 C C . ALA A 1 528 ? 106.102 545.117 91.520 1.00 25.57 ? 582 ALA A C 1 ATOM 3867 O O . ALA A 1 528 ? 106.635 546.175 91.181 1.00 26.38 ? 582 ALA A O 1 ATOM 3868 C CB . ALA A 1 528 ? 105.005 543.604 89.793 1.00 22.07 ? 582 ALA A CB 1 ATOM 3869 N N . VAL A 1 529 ? 106.583 544.366 92.504 1.00 20.58 ? 583 VAL A N 1 ATOM 3870 C CA . VAL A 1 529 ? 107.701 544.768 93.329 1.00 20.98 ? 583 VAL A CA 1 ATOM 3871 C C . VAL A 1 529 ? 108.876 543.865 93.140 1.00 25.52 ? 583 VAL A C 1 ATOM 3872 O O . VAL A 1 529 ? 108.738 542.649 93.149 1.00 26.33 ? 583 VAL A O 1 ATOM 3873 C CB . VAL A 1 529 ? 107.257 544.889 94.828 1.00 25.07 ? 583 VAL A CB 1 ATOM 3874 C CG1 . VAL A 1 529 ? 108.419 545.301 95.738 1.00 24.66 ? 583 VAL A CG1 1 ATOM 3875 C CG2 . VAL A 1 529 ? 106.102 545.874 94.962 1.00 24.95 ? 583 VAL A CG2 1 ATOM 3876 N N . HIS A 1 530 ? 110.043 544.479 93.012 1.00 21.49 ? 584 HIS A N 1 ATOM 3877 C CA . HIS A 1 530 ? 111.312 543.825 92.810 1.00 21.81 ? 584 HIS A CA 1 ATOM 3878 C C . HIS A 1 530 ? 112.290 544.071 93.953 1.00 27.28 ? 584 HIS A C 1 ATOM 3879 O O . HIS A 1 530 ? 111.996 544.807 94.892 1.00 26.49 ? 584 HIS A O 1 ATOM 3880 C CB . HIS A 1 530 ? 111.933 544.320 91.507 1.00 22.66 ? 584 HIS A CB 1 ATOM 3881 C CG . HIS A 1 530 ? 111.195 543.884 90.273 1.00 26.00 ? 584 HIS A CG 1 ATOM 3882 N ND1 . HIS A 1 530 ? 111.654 542.840 89.493 1.00 27.86 ? 584 HIS A ND1 1 ATOM 3883 C CD2 . HIS A 1 530 ? 110.091 544.399 89.696 1.00 27.70 ? 584 HIS A CD2 1 ATOM 3884 C CE1 . HIS A 1 530 ? 110.806 542.731 88.487 1.00 27.17 ? 584 HIS A CE1 1 ATOM 3885 N NE2 . HIS A 1 530 ? 109.841 543.639 88.573 1.00 27.57 ? 584 HIS A NE2 1 ATOM 3886 N N . TYR A 1 531 ? 113.476 543.444 93.843 1.00 23.90 ? 585 TYR A N 1 ATOM 3887 C CA . TYR A 1 531 ? 114.597 543.539 94.764 1.00 21.99 ? 585 TYR A CA 1 ATOM 3888 C C . TYR A 1 531 ? 114.840 545.007 95.143 1.00 22.48 ? 585 TYR A C 1 ATOM 3889 O O . TYR A 1 531 ? 114.808 545.890 94.276 1.00 19.96 ? 585 TYR A O 1 ATOM 3890 C CB . TYR A 1 531 ? 115.836 542.980 94.057 1.00 23.50 ? 585 TYR A CB 1 ATOM 3891 C CG . TYR A 1 531 ? 117.121 543.112 94.836 1.00 24.27 ? 585 TYR A CG 1 ATOM 3892 C CD1 . TYR A 1 531 ? 117.390 542.278 95.912 1.00 26.12 ? 585 TYR A CD1 1 ATOM 3893 C CD2 . TYR A 1 531 ? 118.094 544.035 94.464 1.00 24.69 ? 585 TYR A CD2 1 ATOM 3894 C CE1 . TYR A 1 531 ? 118.581 542.383 96.627 1.00 27.48 ? 585 TYR A CE1 1 ATOM 3895 C CE2 . TYR A 1 531 ? 119.303 544.129 95.155 1.00 25.63 ? 585 TYR A CE2 1 ATOM 3896 C CZ . TYR A 1 531 ? 119.539 543.297 96.238 1.00 32.14 ? 585 TYR A CZ 1 ATOM 3897 O OH . TYR A 1 531 ? 120.709 543.370 96.955 1.00 35.40 ? 585 TYR A OH 1 ATOM 3898 N N . GLY A 1 532 ? 115.030 545.253 96.441 1.00 16.12 ? 586 GLY A N 1 ATOM 3899 C CA . GLY A 1 532 ? 115.292 546.581 96.954 1.00 14.29 ? 586 GLY A CA 1 ATOM 3900 C C . GLY A 1 532 ? 114.045 547.413 97.138 1.00 19.38 ? 586 GLY A C 1 ATOM 3901 O O . GLY A 1 532 ? 114.131 548.557 97.589 1.00 18.57 ? 586 GLY A O 1 ATOM 3902 N N . GLY A 1 533 ? 112.896 546.844 96.772 1.00 19.59 ? 587 GLY A N 1 ATOM 3903 C CA . GLY A 1 533 ? 111.583 547.482 96.834 1.00 20.19 ? 587 GLY A CA 1 ATOM 3904 C C . GLY A 1 533 ? 111.218 548.323 95.626 1.00 25.98 ? 587 GLY A C 1 ATOM 3905 O O . GLY A 1 533 ? 110.210 549.040 95.640 1.00 25.94 ? 587 GLY A O 1 ATOM 3906 N N . TRP A 1 534 ? 112.036 548.261 94.578 1.00 22.42 ? 588 TRP A N 1 ATOM 3907 C CA . TRP A 1 534 ? 111.770 549.005 93.352 1.00 22.55 ? 588 TRP A CA 1 ATOM 3908 C C . TRP A 1 534 ? 110.535 548.432 92.655 1.00 26.76 ? 588 TRP A C 1 ATOM 3909 O O . TRP A 1 534 ? 110.255 547.230 92.754 1.00 26.95 ? 588 TRP A O 1 ATOM 3910 C CB . TRP A 1 534 ? 113.011 548.987 92.425 1.00 20.98 ? 588 TRP A CB 1 ATOM 3911 C CG . TRP A 1 534 ? 114.217 549.631 93.033 1.00 22.01 ? 588 TRP A CG 1 ATOM 3912 C CD1 . TRP A 1 534 ? 115.343 549.004 93.485 1.00 25.24 ? 588 TRP A CD1 1 ATOM 3913 C CD2 . TRP A 1 534 ? 114.392 551.024 93.319 1.00 21.99 ? 588 TRP A CD2 1 ATOM 3914 N NE1 . TRP A 1 534 ? 116.238 549.930 93.979 1.00 24.82 ? 588 TRP A NE1 1 ATOM 3915 C CE2 . TRP A 1 534 ? 115.670 551.176 93.908 1.00 26.20 ? 588 TRP A CE2 1 ATOM 3916 C CE3 . TRP A 1 534 ? 113.616 552.171 93.082 1.00 23.50 ? 588 TRP A CE3 1 ATOM 3917 C CZ2 . TRP A 1 534 ? 116.181 552.422 94.276 1.00 25.72 ? 588 TRP A CZ2 1 ATOM 3918 C CZ3 . TRP A 1 534 ? 114.118 553.399 93.458 1.00 25.54 ? 588 TRP A CZ3 1 ATOM 3919 C CH2 . TRP A 1 534 ? 115.387 553.517 94.048 1.00 26.39 ? 588 TRP A CH2 1 ATOM 3920 N N . GLU A 1 535 ? 109.772 549.297 91.999 1.00 23.42 ? 589 GLU A N 1 ATOM 3921 C CA . GLU A 1 535 ? 108.601 548.842 91.255 1.00 23.55 ? 589 GLU A CA 1 ATOM 3922 C C . GLU A 1 535 ? 109.037 548.320 89.891 1.00 28.05 ? 589 GLU A C 1 ATOM 3923 O O . GLU A 1 535 ? 110.081 548.730 89.353 1.00 25.44 ? 589 GLU A O 1 ATOM 3924 C CB . GLU A 1 535 ? 107.613 549.978 91.029 1.00 24.34 ? 589 GLU A CB 1 ATOM 3925 C CG . GLU A 1 535 ? 106.881 550.433 92.272 1.00 28.87 ? 589 GLU A CG 1 ATOM 3926 C CD . GLU A 1 535 ? 105.775 551.407 91.926 1.00 34.87 ? 589 GLU A CD 1 ATOM 3927 O OE1 . GLU A 1 535 ? 106.091 552.547 91.513 1.00 29.94 ? 589 GLU A OE1 1 ATOM 3928 O OE2 . GLU A 1 535 ? 104.597 550.993 91.972 1.00 22.29 ? 589 GLU A OE2 1 ATOM 3929 N N . HIS A 1 536 ? 108.194 547.463 89.300 1.00 25.17 ? 590 HIS A N 1 ATOM 3930 C CA . HIS A 1 536 ? 108.435 546.987 87.953 1.00 24.17 ? 590 HIS A CA 1 ATOM 3931 C C . HIS A 1 536 ? 108.642 548.154 86.987 1.00 27.02 ? 590 HIS A C 1 ATOM 3932 O O . HIS A 1 536 ? 109.491 548.064 86.113 1.00 26.32 ? 590 HIS A O 1 ATOM 3933 C CB . HIS A 1 536 ? 107.273 546.123 87.475 1.00 24.23 ? 590 HIS A CB 1 ATOM 3934 C CG . HIS A 1 536 ? 107.609 545.452 86.197 1.00 26.45 ? 590 HIS A CG 1 ATOM 3935 N ND1 . HIS A 1 536 ? 108.594 544.498 86.143 1.00 27.36 ? 590 HIS A ND1 1 ATOM 3936 C CD2 . HIS A 1 536 ? 107.193 545.722 84.943 1.00 26.65 ? 590 HIS A CD2 1 ATOM 3937 C CE1 . HIS A 1 536 ? 108.696 544.156 84.873 1.00 26.09 ? 590 HIS A CE1 1 ATOM 3938 N NE2 . HIS A 1 536 ? 107.881 544.871 84.117 1.00 26.32 ? 590 HIS A NE2 1 ATOM 3939 N N . ARG A 1 537 ? 107.874 549.242 87.154 1.00 25.66 ? 591 ARG A N 1 ATOM 3940 C CA . ARG A 1 537 ? 107.977 550.403 86.277 1.00 25.78 ? 591 ARG A CA 1 ATOM 3941 C C . ARG A 1 537 ? 109.398 550.950 86.281 1.00 28.91 ? 591 ARG A C 1 ATOM 3942 O O . ARG A 1 537 ? 109.815 551.485 85.277 1.00 27.58 ? 591 ARG A O 1 ATOM 3943 C CB . ARG A 1 537 ? 106.951 551.500 86.626 1.00 20.97 ? 591 ARG A CB 1 ATOM 3944 C CG . ARG A 1 537 ? 107.446 552.588 87.587 1.00 24.61 ? 591 ARG A CG 1 ATOM 3945 C CD . ARG A 1 537 ? 106.349 553.571 87.962 1.00 23.79 ? 591 ARG A CD 1 ATOM 3946 N NE . ARG A 1 537 ? 105.384 552.919 88.841 1.00 22.24 ? 591 ARG A NE 1 ATOM 3947 C CZ . ARG A 1 537 ? 104.128 552.614 88.521 1.00 33.80 ? 591 ARG A CZ 1 ATOM 3948 N NH1 . ARG A 1 537 ? 103.635 552.946 87.329 1.00 12.38 ? 591 ARG A NH1 1 ATOM 3949 N NH2 . ARG A 1 537 ? 103.338 552.024 89.409 1.00 28.37 ? 591 ARG A NH2 1 ATOM 3950 N N . ASP A 1 538 ? 110.129 550.829 87.393 1.00 24.86 ? 592 ASP A N 1 ATOM 3951 C CA . ASP A 1 538 ? 111.476 551.404 87.474 1.00 23.62 ? 592 ASP A CA 1 ATOM 3952 C C . ASP A 1 538 ? 112.499 550.610 86.671 1.00 23.31 ? 592 ASP A C 1 ATOM 3953 O O . ASP A 1 538 ? 113.447 551.184 86.135 1.00 19.72 ? 592 ASP A O 1 ATOM 3954 C CB . ASP A 1 538 ? 111.957 551.475 88.947 1.00 25.12 ? 592 ASP A CB 1 ATOM 3955 C CG . ASP A 1 538 ? 111.093 552.319 89.828 1.00 28.71 ? 592 ASP A CG 1 ATOM 3956 O OD1 . ASP A 1 538 ? 110.854 553.470 89.472 1.00 29.94 ? 592 ASP A OD1 1 ATOM 3957 O OD2 . ASP A 1 538 ? 110.658 551.821 90.886 1.00 32.44 ? 592 ASP A OD2 1 ATOM 3958 N N . ILE A 1 539 ? 112.322 549.291 86.620 1.00 20.82 ? 593 ILE A N 1 ATOM 3959 C CA . ILE A 1 539 ? 113.324 548.387 86.084 1.00 20.96 ? 593 ILE A CA 1 ATOM 3960 C C . ILE A 1 539 ? 112.966 547.702 84.770 1.00 26.58 ? 593 ILE A C 1 ATOM 3961 O O . ILE A 1 539 ? 113.795 546.971 84.228 1.00 28.03 ? 593 ILE A O 1 ATOM 3962 C CB . ILE A 1 539 ? 113.602 547.337 87.209 1.00 24.38 ? 593 ILE A CB 1 ATOM 3963 C CG1 . ILE A 1 539 ? 112.430 546.315 87.384 1.00 25.01 ? 593 ILE A CG1 1 ATOM 3964 C CG2 . ILE A 1 539 ? 113.921 548.014 88.570 1.00 24.77 ? 593 ILE A CG2 1 ATOM 3965 C CD1 . ILE A 1 539 ? 112.398 545.141 86.388 1.00 11.69 ? 593 ILE A CD1 1 ATOM 3966 N N . HIS A 1 540 ? 111.737 547.866 84.280 1.00 21.73 ? 594 HIS A N 1 ATOM 3967 C CA . HIS A 1 540 ? 111.223 547.067 83.177 1.00 20.83 ? 594 HIS A CA 1 ATOM 3968 C C . HIS A 1 540 ? 112.231 546.721 82.046 1.00 26.95 ? 594 HIS A C 1 ATOM 3969 O O . HIS A 1 540 ? 112.409 545.535 81.712 1.00 26.99 ? 594 HIS A O 1 ATOM 3970 C CB . HIS A 1 540 ? 109.946 547.677 82.580 1.00 20.62 ? 594 HIS A CB 1 ATOM 3971 C CG . HIS A 1 540 ? 109.386 546.865 81.450 1.00 22.81 ? 594 HIS A CG 1 ATOM 3972 N ND1 . HIS A 1 540 ? 108.511 545.826 81.671 1.00 23.59 ? 594 HIS A ND1 1 ATOM 3973 C CD2 . HIS A 1 540 ? 109.617 546.959 80.120 1.00 23.80 ? 594 HIS A CD2 1 ATOM 3974 C CE1 . HIS A 1 540 ? 108.255 545.305 80.486 1.00 23.19 ? 594 HIS A CE1 1 ATOM 3975 N NE2 . HIS A 1 540 ? 108.888 545.967 79.518 1.00 23.22 ? 594 HIS A NE2 1 ATOM 3976 N N . ASN A 1 541 ? 112.865 547.724 81.461 1.00 23.69 ? 595 ASN A N 1 ATOM 3977 C CA . ASN A 1 541 ? 113.695 547.480 80.284 1.00 24.49 ? 595 ASN A CA 1 ATOM 3978 C C . ASN A 1 541 ? 115.023 546.734 80.545 1.00 29.08 ? 595 ASN A C 1 ATOM 3979 O O . ASN A 1 541 ? 115.680 546.359 79.582 1.00 28.62 ? 595 ASN A O 1 ATOM 3980 C CB . ASN A 1 541 ? 113.922 548.771 79.512 1.00 20.28 ? 595 ASN A CB 1 ATOM 3981 C CG . ASN A 1 541 ? 112.703 549.171 78.744 1.00 24.36 ? 595 ASN A CG 1 ATOM 3982 O OD1 . ASN A 1 541 ? 111.777 548.370 78.515 1.00 15.50 ? 595 ASN A OD1 1 ATOM 3983 N ND2 . ASN A 1 541 ? 112.646 550.427 78.378 1.00 12.72 ? 595 ASN A ND2 1 ATOM 3984 N N . ILE A 1 542 ? 115.390 546.478 81.810 1.00 24.27 ? 596 ILE A N 1 ATOM 3985 C CA . ILE A 1 542 ? 116.588 545.683 82.080 1.00 23.14 ? 596 ILE A CA 1 ATOM 3986 C C . ILE A 1 542 ? 116.244 544.260 82.545 1.00 26.27 ? 596 ILE A C 1 ATOM 3987 O O . ILE A 1 542 ? 117.164 543.480 82.766 1.00 25.96 ? 596 ILE A O 1 ATOM 3988 C CB . ILE A 1 542 ? 117.635 546.348 83.009 1.00 25.01 ? 596 ILE A CB 1 ATOM 3989 C CG1 . ILE A 1 542 ? 117.049 546.631 84.415 1.00 24.88 ? 596 ILE A CG1 1 ATOM 3990 C CG2 . ILE A 1 542 ? 118.198 547.586 82.354 1.00 23.67 ? 596 ILE A CG2 1 ATOM 3991 C CD1 . ILE A 1 542 ? 118.041 547.267 85.449 1.00 24.05 ? 596 ILE A CD1 1 ATOM 3992 N N . TYR A 1 543 ? 114.960 543.908 82.684 1.00 21.87 ? 597 TYR A N 1 ATOM 3993 C CA . TYR A 1 543 ? 114.593 542.561 83.105 1.00 21.14 ? 597 TYR A CA 1 ATOM 3994 C C . TYR A 1 543 ? 115.214 541.538 82.167 1.00 22.52 ? 597 TYR A C 1 ATOM 3995 O O . TYR A 1 543 ? 115.893 540.604 82.608 1.00 22.29 ? 597 TYR A O 1 ATOM 3996 C CB . TYR A 1 543 ? 113.052 542.402 83.166 1.00 21.37 ? 597 TYR A CB 1 ATOM 3997 C CG . TYR A 1 543 ? 112.601 541.064 83.724 1.00 20.31 ? 597 TYR A CG 1 ATOM 3998 C CD1 . TYR A 1 543 ? 112.444 539.956 82.897 1.00 22.56 ? 597 TYR A CD1 1 ATOM 3999 C CD2 . TYR A 1 543 ? 112.307 540.914 85.078 1.00 18.64 ? 597 TYR A CD2 1 ATOM 4000 C CE1 . TYR A 1 543 ? 112.046 538.719 83.410 1.00 24.15 ? 597 TYR A CE1 1 ATOM 4001 C CE2 . TYR A 1 543 ? 111.906 539.685 85.602 1.00 17.33 ? 597 TYR A CE2 1 ATOM 4002 C CZ . TYR A 1 543 ? 111.784 538.590 84.768 1.00 22.96 ? 597 TYR A CZ 1 ATOM 4003 O OH . TYR A 1 543 ? 111.392 537.372 85.282 1.00 12.70 ? 597 TYR A OH 1 ATOM 4004 N N . GLY A 1 544 ? 114.970 541.727 80.879 1.00 18.63 ? 598 GLY A N 1 ATOM 4005 C CA . GLY A 1 544 ? 115.448 540.809 79.852 1.00 18.09 ? 598 GLY A CA 1 ATOM 4006 C C . GLY A 1 544 ? 116.941 540.617 79.823 1.00 22.75 ? 598 GLY A C 1 ATOM 4007 O O . GLY A 1 544 ? 117.431 539.488 79.694 1.00 23.55 ? 598 GLY A O 1 ATOM 4008 N N . LEU A 1 545 ? 117.670 541.735 79.915 1.00 18.17 ? 599 LEU A N 1 ATOM 4009 C CA . LEU A 1 545 ? 119.119 541.755 79.981 1.00 16.83 ? 599 LEU A CA 1 ATOM 4010 C C . LEU A 1 545 ? 119.616 540.870 81.152 1.00 18.58 ? 599 LEU A C 1 ATOM 4011 O O . LEU A 1 545 ? 120.611 540.187 81.028 1.00 14.46 ? 599 LEU A O 1 ATOM 4012 C CB . LEU A 1 545 ? 119.597 543.209 80.176 1.00 16.42 ? 599 LEU A CB 1 ATOM 4013 C CG . LEU A 1 545 ? 121.127 543.392 80.427 1.00 20.79 ? 599 LEU A CG 1 ATOM 4014 C CD1 . LEU A 1 545 ? 121.627 544.694 79.915 1.00 19.46 ? 599 LEU A CD1 1 ATOM 4015 C CD2 . LEU A 1 545 ? 121.476 543.296 81.916 1.00 22.20 ? 599 LEU A CD2 1 ATOM 4016 N N . TYR A 1 546 ? 118.964 540.965 82.309 1.00 17.32 ? 600 TYR A N 1 ATOM 4017 C CA . TYR A 1 546 ? 119.407 540.216 83.453 1.00 17.69 ? 600 TYR A CA 1 ATOM 4018 C C . TYR A 1 546 ? 119.208 538.708 83.244 1.00 22.56 ? 600 TYR A C 1 ATOM 4019 O O . TYR A 1 546 ? 120.015 537.897 83.717 1.00 24.49 ? 600 TYR A O 1 ATOM 4020 C CB . TYR A 1 546 ? 118.671 540.712 84.689 1.00 19.57 ? 600 TYR A CB 1 ATOM 4021 C CG . TYR A 1 546 ? 119.232 541.933 85.398 1.00 21.78 ? 600 TYR A CG 1 ATOM 4022 C CD1 . TYR A 1 546 ? 120.589 542.024 85.718 1.00 24.08 ? 600 TYR A CD1 1 ATOM 4023 C CD2 . TYR A 1 546 ? 118.386 542.929 85.876 1.00 22.43 ? 600 TYR A CD2 1 ATOM 4024 C CE1 . TYR A 1 546 ? 121.084 543.080 86.495 1.00 24.30 ? 600 TYR A CE1 1 ATOM 4025 C CE2 . TYR A 1 546 ? 118.865 543.979 86.655 1.00 22.68 ? 600 TYR A CE2 1 ATOM 4026 C CZ . TYR A 1 546 ? 120.213 544.051 86.965 1.00 28.33 ? 600 TYR A CZ 1 ATOM 4027 O OH . TYR A 1 546 ? 120.663 545.102 87.716 1.00 24.35 ? 600 TYR A OH 1 ATOM 4028 N N . VAL A 1 547 ? 118.151 538.337 82.524 1.00 17.18 ? 601 VAL A N 1 ATOM 4029 C CA . VAL A 1 547 ? 117.891 536.935 82.200 1.00 16.08 ? 601 VAL A CA 1 ATOM 4030 C C . VAL A 1 547 ? 119.031 536.442 81.313 1.00 22.11 ? 601 VAL A C 1 ATOM 4031 O O . VAL A 1 547 ? 119.613 535.396 81.567 1.00 24.50 ? 601 VAL A O 1 ATOM 4032 C CB . VAL A 1 547 ? 116.534 536.741 81.487 1.00 19.02 ? 601 VAL A CB 1 ATOM 4033 C CG1 . VAL A 1 547 ? 116.360 535.291 81.045 1.00 19.01 ? 601 VAL A CG1 1 ATOM 4034 C CG2 . VAL A 1 547 ? 115.359 537.206 82.344 1.00 18.26 ? 601 VAL A CG2 1 ATOM 4035 N N . HIS A 1 548 ? 119.354 537.212 80.288 1.00 17.62 ? 602 HIS A N 1 ATOM 4036 C CA . HIS A 1 548 ? 120.406 536.933 79.322 1.00 17.58 ? 602 HIS A CA 1 ATOM 4037 C C . HIS A 1 548 ? 121.783 536.812 80.013 1.00 22.19 ? 602 HIS A C 1 ATOM 4038 O O . HIS A 1 548 ? 122.513 535.833 79.805 1.00 22.26 ? 602 HIS A O 1 ATOM 4039 C CB . HIS A 1 548 ? 120.411 538.080 78.305 1.00 18.36 ? 602 HIS A CB 1 ATOM 4040 C CG . HIS A 1 548 ? 121.092 537.780 77.009 1.00 21.28 ? 602 HIS A CG 1 ATOM 4041 N ND1 . HIS A 1 548 ? 121.232 538.755 76.024 1.00 22.47 ? 602 HIS A ND1 1 ATOM 4042 C CD2 . HIS A 1 548 ? 121.655 536.636 76.571 1.00 22.57 ? 602 HIS A CD2 1 ATOM 4043 C CE1 . HIS A 1 548 ? 121.838 538.162 75.015 1.00 22.12 ? 602 HIS A CE1 1 ATOM 4044 N NE2 . HIS A 1 548 ? 122.087 536.878 75.289 1.00 22.79 ? 602 HIS A NE2 1 ATOM 4045 N N . MET A 1 549 ? 122.084 537.765 80.908 1.00 18.65 ? 603 MET A N 1 ATOM 4046 C CA . MET A 1 549 ? 123.306 537.808 81.726 1.00 17.77 ? 603 MET A CA 1 ATOM 4047 C C . MET A 1 549 ? 123.443 536.554 82.578 1.00 23.37 ? 603 MET A C 1 ATOM 4048 O O . MET A 1 549 ? 124.506 535.913 82.579 1.00 23.67 ? 603 MET A O 1 ATOM 4049 C CB . MET A 1 549 ? 123.259 539.029 82.654 1.00 19.20 ? 603 MET A CB 1 ATOM 4050 C CG . MET A 1 549 ? 124.462 539.161 83.554 1.00 23.08 ? 603 MET A CG 1 ATOM 4051 S SD . MET A 1 549 ? 124.127 540.308 84.894 1.00 27.91 ? 603 MET A SD 1 ATOM 4052 C CE . MET A 1 549 ? 124.149 541.873 84.040 1.00 23.41 ? 603 MET A CE 1 ATOM 4053 N N . ALA A 1 550 ? 122.370 536.212 83.311 1.00 20.55 ? 604 ALA A N 1 ATOM 4054 C CA . ALA A 1 550 ? 122.403 535.061 84.204 1.00 21.69 ? 604 ALA A CA 1 ATOM 4055 C C . ALA A 1 550 ? 122.531 533.754 83.463 1.00 28.45 ? 604 ALA A C 1 ATOM 4056 O O . ALA A 1 550 ? 123.214 532.845 83.931 1.00 29.66 ? 604 ALA A O 1 ATOM 4057 C CB . ALA A 1 550 ? 121.180 535.048 85.090 1.00 22.65 ? 604 ALA A CB 1 ATOM 4058 N N . THR A 1 551 ? 121.886 533.650 82.305 1.00 26.06 ? 605 THR A N 1 ATOM 4059 C CA . THR A 1 551 ? 121.974 532.451 81.465 1.00 25.51 ? 605 THR A CA 1 ATOM 4060 C C . THR A 1 551 ? 123.403 532.282 80.941 1.00 29.11 ? 605 THR A C 1 ATOM 4061 O O . THR A 1 551 ? 123.996 531.208 81.122 1.00 29.77 ? 605 THR A O 1 ATOM 4062 C CB . THR A 1 551 ? 120.908 532.484 80.344 1.00 23.99 ? 605 THR A CB 1 ATOM 4063 O OG1 . THR A 1 551 ? 119.598 532.632 80.921 1.00 22.30 ? 605 THR A OG1 1 ATOM 4064 C CG2 . THR A 1 551 ? 120.945 531.259 79.491 1.00 12.33 ? 605 THR A CG2 1 ATOM 4065 N N . ALA A 1 552 ? 123.974 533.355 80.362 1.00 25.17 ? 606 ALA A N 1 ATOM 4066 C CA . ALA A 1 552 ? 125.371 533.344 79.895 1.00 25.43 ? 606 ALA A CA 1 ATOM 4067 C C . ALA A 1 552 ? 126.350 532.965 81.034 1.00 25.14 ? 606 ALA A C 1 ATOM 4068 O O . ALA A 1 552 ? 127.224 532.126 80.839 1.00 25.36 ? 606 ALA A O 1 ATOM 4069 C CB . ALA A 1 552 ? 125.742 534.693 79.284 1.00 26.66 ? 606 ALA A CB 1 ATOM 4070 N N . ASP A 1 553 ? 126.159 533.526 82.227 1.00 21.07 ? 607 ASP A N 1 ATOM 4071 C CA A ASP A 1 553 ? 127.021 533.180 83.356 0.50 20.13 ? 607 ASP A CA 1 ATOM 4072 C CA B ASP A 1 553 ? 126.960 533.220 83.418 0.50 21.20 ? 607 ASP A CA 1 ATOM 4073 C C . ASP A 1 553 ? 126.848 531.719 83.735 1.00 25.05 ? 607 ASP A C 1 ATOM 4074 O O . ASP A 1 553 ? 127.846 531.064 84.062 1.00 23.61 ? 607 ASP A O 1 ATOM 4075 C CB A ASP A 1 553 ? 126.839 534.127 84.541 0.50 21.26 ? 607 ASP A CB 1 ATOM 4076 C CB B ASP A 1 553 ? 126.437 534.055 84.593 0.50 23.72 ? 607 ASP A CB 1 ATOM 4077 C CG A ASP A 1 553 ? 127.538 535.471 84.374 0.50 23.45 ? 607 ASP A CG 1 ATOM 4078 C CG B ASP A 1 553 ? 127.235 533.965 85.872 0.50 40.51 ? 607 ASP A CG 1 ATOM 4079 O OD1 A ASP A 1 553 ? 128.672 535.495 83.813 0.50 22.88 ? 607 ASP A OD1 1 ATOM 4080 O OD1 B ASP A 1 553 ? 128.473 533.748 85.791 0.50 42.15 ? 607 ASP A OD1 1 ATOM 4081 O OD2 A ASP A 1 553 ? 127.008 536.479 84.885 0.50 21.13 ? 607 ASP A OD2 1 ATOM 4082 O OD2 B ASP A 1 553 ? 126.630 534.131 86.961 0.50 47.63 ? 607 ASP A OD2 1 ATOM 4083 N N . GLY A 1 554 ? 125.622 531.183 83.604 1.00 22.32 ? 608 GLY A N 1 ATOM 4084 C CA . GLY A 1 554 ? 125.379 529.769 83.857 1.00 21.60 ? 608 GLY A CA 1 ATOM 4085 C C . GLY A 1 554 ? 126.189 528.866 82.949 1.00 27.94 ? 608 GLY A C 1 ATOM 4086 O O . GLY A 1 554 ? 126.795 527.899 83.423 1.00 28.40 ? 608 GLY A O 1 ATOM 4087 N N . LEU A 1 555 ? 126.247 529.189 81.642 1.00 24.99 ? 609 LEU A N 1 ATOM 4088 C CA . LEU A 1 555 ? 126.989 528.380 80.675 1.00 24.39 ? 609 LEU A CA 1 ATOM 4089 C C . LEU A 1 555 ? 128.487 528.476 80.879 1.00 26.70 ? 609 LEU A C 1 ATOM 4090 O O . LEU A 1 555 ? 129.207 527.498 80.652 1.00 26.73 ? 609 LEU A O 1 ATOM 4091 C CB . LEU A 1 555 ? 126.600 528.758 79.246 1.00 24.83 ? 609 LEU A CB 1 ATOM 4092 C CG . LEU A 1 555 ? 125.111 528.591 78.896 1.00 29.26 ? 609 LEU A CG 1 ATOM 4093 C CD1 . LEU A 1 555 ? 124.858 528.953 77.453 1.00 28.19 ? 609 LEU A CD1 1 ATOM 4094 C CD2 . LEU A 1 555 ? 124.590 527.126 79.179 1.00 31.26 ? 609 LEU A CD2 1 ATOM 4095 N N . ILE A 1 556 ? 128.959 529.652 81.314 1.00 21.58 ? 610 ILE A N 1 ATOM 4096 C CA . ILE A 1 556 ? 130.365 529.817 81.658 1.00 20.79 ? 610 ILE A CA 1 ATOM 4097 C C . ILE A 1 556 ? 130.704 528.979 82.906 1.00 25.96 ? 610 ILE A C 1 ATOM 4098 O O . ILE A 1 556 ? 131.669 528.220 82.902 1.00 25.63 ? 610 ILE A O 1 ATOM 4099 C CB . ILE A 1 556 ? 130.711 531.312 81.885 1.00 22.69 ? 610 ILE A CB 1 ATOM 4100 C CG1 . ILE A 1 556 ? 130.560 532.124 80.588 1.00 22.51 ? 610 ILE A CG1 1 ATOM 4101 C CG2 . ILE A 1 556 ? 132.133 531.478 82.448 1.00 20.90 ? 610 ILE A CG2 1 ATOM 4102 C CD1 . ILE A 1 556 ? 130.728 533.649 80.785 1.00 16.92 ? 610 ILE A CD1 1 ATOM 4103 N N . GLN A 1 557 ? 129.923 529.147 83.970 1.00 24.96 ? 611 GLN A N 1 ATOM 4104 C CA . GLN A 1 557 ? 130.161 528.489 85.243 1.00 25.88 ? 611 GLN A CA 1 ATOM 4105 C C . GLN A 1 557 ? 130.127 526.971 85.170 1.00 30.20 ? 611 GLN A C 1 ATOM 4106 O O . GLN A 1 557 ? 130.960 526.316 85.801 1.00 29.24 ? 611 GLN A O 1 ATOM 4107 C CB . GLN A 1 557 ? 129.131 528.940 86.252 1.00 27.74 ? 611 GLN A CB 1 ATOM 4108 C CG . GLN A 1 557 ? 129.395 530.294 86.822 1.00 47.37 ? 611 GLN A CG 1 ATOM 4109 C CD . GLN A 1 557 ? 128.278 530.686 87.775 1.00 65.96 ? 611 GLN A CD 1 ATOM 4110 O OE1 . GLN A 1 557 ? 127.546 529.848 88.373 1.00 49.23 ? 611 GLN A OE1 1 ATOM 4111 N NE2 . GLN A 1 557 ? 128.119 531.989 87.941 1.00 65.21 ? 611 GLN A NE2 1 ATOM 4112 N N . ARG A 1 558 ? 129.159 526.406 84.418 1.00 26.35 ? 612 ARG A N 1 ATOM 4113 C CA . ARG A 1 558 ? 129.032 524.959 84.303 1.00 25.28 ? 612 ARG A CA 1 ATOM 4114 C C . ARG A 1 558 ? 130.296 524.308 83.737 1.00 32.50 ? 612 ARG A C 1 ATOM 4115 O O . ARG A 1 558 ? 130.491 523.108 83.922 1.00 34.99 ? 612 ARG A O 1 ATOM 4116 C CB . ARG A 1 558 ? 127.795 524.581 83.483 1.00 22.38 ? 612 ARG A CB 1 ATOM 4117 C CG . ARG A 1 558 ? 128.069 524.555 81.990 1.00 23.73 ? 612 ARG A CG 1 ATOM 4118 C CD . ARG A 1 558 ? 126.854 524.281 81.153 1.00 32.52 ? 612 ARG A CD 1 ATOM 4119 N NE . ARG A 1 558 ? 127.227 524.412 79.745 1.00 36.01 ? 612 ARG A NE 1 ATOM 4120 C CZ . ARG A 1 558 ? 126.465 524.109 78.698 1.00 35.32 ? 612 ARG A CZ 1 ATOM 4121 N NH1 . ARG A 1 558 ? 125.240 523.633 78.873 1.00 18.38 ? 612 ARG A NH1 1 ATOM 4122 N NH2 . ARG A 1 558 ? 126.923 524.280 77.468 1.00 17.93 ? 612 ARG A NH2 1 ATOM 4123 N N . SER A 1 559 ? 131.129 525.070 83.017 1.00 27.72 ? 613 SER A N 1 ATOM 4124 C CA . SER A 1 559 ? 132.362 524.535 82.445 1.00 26.11 ? 613 SER A CA 1 ATOM 4125 C C . SER A 1 559 ? 133.595 524.839 83.295 1.00 29.17 ? 613 SER A C 1 ATOM 4126 O O . SER A 1 559 ? 134.707 524.666 82.831 1.00 30.44 ? 613 SER A O 1 ATOM 4127 C CB . SER A 1 559 ? 132.567 525.141 81.066 1.00 28.10 ? 613 SER A CB 1 ATOM 4128 O OG . SER A 1 559 ? 132.916 526.513 81.154 1.00 30.13 ? 613 SER A OG 1 ATOM 4129 N N . GLY A 1 560 ? 133.405 525.378 84.479 1.00 26.85 ? 614 GLY A N 1 ATOM 4130 C CA . GLY A 1 560 ? 134.502 525.804 85.341 1.00 26.15 ? 614 GLY A CA 1 ATOM 4131 C C . GLY A 1 560 ? 135.170 527.058 84.832 1.00 30.43 ? 614 GLY A C 1 ATOM 4132 O O . GLY A 1 560 ? 136.377 527.231 85.035 1.00 32.41 ? 614 GLY A O 1 ATOM 4133 N N . GLY A 1 561 ? 134.400 527.894 84.126 1.00 24.23 ? 615 GLY A N 1 ATOM 4134 C CA . GLY A 1 561 ? 134.861 529.171 83.601 1.00 23.06 ? 615 GLY A CA 1 ATOM 4135 C C . GLY A 1 561 ? 135.658 529.144 82.317 1.00 25.86 ? 615 GLY A C 1 ATOM 4136 O O . GLY A 1 561 ? 136.157 530.187 81.893 1.00 24.89 ? 615 GLY A O 1 ATOM 4137 N N . ILE A 1 562 ? 135.713 528.002 81.654 1.00 23.04 ? 616 ILE A N 1 ATOM 4138 C CA . ILE A 1 562 ? 136.517 527.799 80.450 1.00 23.59 ? 616 ILE A CA 1 ATOM 4139 C C . ILE A 1 562 ? 135.800 528.084 79.121 1.00 25.11 ? 616 ILE A C 1 ATOM 4140 O O . ILE A 1 562 ? 136.411 528.617 78.190 1.00 22.98 ? 616 ILE A O 1 ATOM 4141 C CB . ILE A 1 562 ? 137.080 526.335 80.481 1.00 27.52 ? 616 ILE A CB 1 ATOM 4142 C CG1 . ILE A 1 562 ? 138.004 526.145 81.691 1.00 28.77 ? 616 ILE A CG1 1 ATOM 4143 C CG2 . ILE A 1 562 ? 137.807 525.945 79.159 1.00 26.35 ? 616 ILE A CG2 1 ATOM 4144 C CD1 . ILE A 1 562 ? 138.315 524.712 82.012 1.00 45.07 ? 616 ILE A CD1 1 ATOM 4145 N N . GLU A 1 563 ? 134.560 527.634 78.998 1.00 22.86 ? 617 GLU A N 1 ATOM 4146 C CA . GLU A 1 563 ? 133.806 527.695 77.745 1.00 22.43 ? 617 GLU A CA 1 ATOM 4147 C C . GLU A 1 563 ? 133.072 528.974 77.549 1.00 27.36 ? 617 GLU A C 1 ATOM 4148 O O . GLU A 1 563 ? 132.389 529.422 78.462 1.00 27.93 ? 617 GLU A O 1 ATOM 4149 C CB . GLU A 1 563 ? 132.803 526.532 77.658 1.00 24.30 ? 617 GLU A CB 1 ATOM 4150 C CG . GLU A 1 563 ? 133.446 525.151 77.575 1.00 36.96 ? 617 GLU A CG 1 ATOM 4151 C CD . GLU A 1 563 ? 134.079 524.828 76.244 1.00 44.46 ? 617 GLU A CD 1 ATOM 4152 O OE1 . GLU A 1 563 ? 133.747 525.501 75.243 1.00 30.52 ? 617 GLU A OE1 1 ATOM 4153 O OE2 . GLU A 1 563 ? 134.908 523.897 76.199 1.00 46.61 ? 617 GLU A OE2 1 ATOM 4154 N N . ARG A 1 564 ? 133.140 529.532 76.333 1.00 24.22 ? 618 ARG A N 1 ATOM 4155 C CA . ARG A 1 564 ? 132.398 530.748 76.023 1.00 22.80 ? 618 ARG A CA 1 ATOM 4156 C C . ARG A 1 564 ? 130.933 530.389 75.874 1.00 23.17 ? 618 ARG A C 1 ATOM 4157 O O . ARG A 1 564 ? 130.602 529.297 75.415 1.00 23.09 ? 618 ARG A O 1 ATOM 4158 C CB . ARG A 1 564 ? 132.926 531.461 74.777 1.00 19.35 ? 618 ARG A CB 1 ATOM 4159 C CG . ARG A 1 564 ? 134.415 531.746 74.823 1.00 13.48 ? 618 ARG A CG 1 ATOM 4160 C CD . ARG A 1 564 ? 134.763 532.927 73.963 1.00 14.85 ? 618 ARG A CD 1 ATOM 4161 N NE . ARG A 1 564 ? 134.502 532.777 72.512 1.00 18.62 ? 618 ARG A NE 1 ATOM 4162 C CZ . ARG A 1 564 ? 135.390 532.385 71.596 1.00 34.52 ? 618 ARG A CZ 1 ATOM 4163 N NH1 . ARG A 1 564 ? 136.579 531.920 71.965 1.00 23.63 ? 618 ARG A NH1 1 ATOM 4164 N NH2 . ARG A 1 564 ? 135.085 532.433 70.302 1.00 22.42 ? 618 ARG A NH2 1 ATOM 4165 N N . PRO A 1 565 ? 130.046 531.280 76.307 1.00 18.65 ? 619 PRO A N 1 ATOM 4166 C CA . PRO A 1 565 ? 128.601 530.966 76.229 1.00 18.59 ? 619 PRO A CA 1 ATOM 4167 C C . PRO A 1 565 ? 127.981 531.191 74.855 1.00 20.99 ? 619 PRO A C 1 ATOM 4168 O O . PRO A 1 565 ? 128.551 531.907 74.052 1.00 19.93 ? 619 PRO A O 1 ATOM 4169 C CB . PRO A 1 565 ? 127.990 531.996 77.166 1.00 20.72 ? 619 PRO A CB 1 ATOM 4170 C CG . PRO A 1 565 ? 128.972 533.207 77.089 1.00 24.58 ? 619 PRO A CG 1 ATOM 4171 C CD . PRO A 1 565 ? 130.310 532.634 76.852 1.00 19.86 ? 619 PRO A CD 1 ATOM 4172 N N . PHE A 1 566 ? 126.793 530.622 74.612 1.00 15.42 ? 620 PHE A N 1 ATOM 4173 C CA . PHE A 1 566 ? 125.974 531.016 73.505 1.00 14.60 ? 620 PHE A CA 1 ATOM 4174 C C . PHE A 1 566 ? 124.560 531.093 74.003 1.00 18.44 ? 620 PHE A C 1 ATOM 4175 O O . PHE A 1 566 ? 123.948 530.070 74.334 1.00 16.72 ? 620 PHE A O 1 ATOM 4176 C CB . PHE A 1 566 ? 126.089 530.208 72.204 1.00 16.06 ? 620 PHE A CB 1 ATOM 4177 C CG . PHE A 1 566 ? 125.022 530.694 71.240 1.00 16.70 ? 620 PHE A CG 1 ATOM 4178 C CD1 . PHE A 1 566 ? 125.152 531.923 70.603 1.00 17.46 ? 620 PHE A CD1 1 ATOM 4179 C CD2 . PHE A 1 566 ? 123.804 530.010 71.115 1.00 16.66 ? 620 PHE A CD2 1 ATOM 4180 C CE1 . PHE A 1 566 ? 124.136 532.416 69.790 1.00 18.06 ? 620 PHE A CE1 1 ATOM 4181 C CE2 . PHE A 1 566 ? 122.785 530.509 70.305 1.00 18.52 ? 620 PHE A CE2 1 ATOM 4182 C CZ . PHE A 1 566 ? 122.957 531.710 69.648 1.00 16.86 ? 620 PHE A CZ 1 ATOM 4183 N N . VAL A 1 567 ? 124.047 532.315 74.052 1.00 15.45 ? 621 VAL A N 1 ATOM 4184 C CA . VAL A 1 567 ? 122.696 532.574 74.450 1.00 15.74 ? 621 VAL A CA 1 ATOM 4185 C C . VAL A 1 567 ? 122.034 533.542 73.493 1.00 21.57 ? 621 VAL A C 1 ATOM 4186 O O . VAL A 1 567 ? 122.561 534.644 73.258 1.00 20.89 ? 621 VAL A O 1 ATOM 4187 C CB . VAL A 1 567 ? 122.598 533.112 75.885 1.00 19.36 ? 621 VAL A CB 1 ATOM 4188 C CG1 . VAL A 1 567 ? 121.139 533.178 76.302 1.00 17.95 ? 621 VAL A CG1 1 ATOM 4189 C CG2 . VAL A 1 567 ? 123.423 532.277 76.881 1.00 18.64 ? 621 VAL A CG2 1 ATOM 4190 N N . LEU A 1 568 ? 120.867 533.136 72.948 1.00 18.25 ? 622 LEU A N 1 ATOM 4191 C CA . LEU A 1 568 ? 120.021 534.016 72.132 1.00 17.93 ? 622 LEU A CA 1 ATOM 4192 C C . LEU A 1 568 ? 118.944 534.591 73.040 1.00 22.90 ? 622 LEU A C 1 ATOM 4193 O O . LEU A 1 568 ? 118.326 533.843 73.790 1.00 22.22 ? 622 LEU A O 1 ATOM 4194 C CB . LEU A 1 568 ? 119.369 533.275 70.943 1.00 17.88 ? 622 LEU A CB 1 ATOM 4195 C CG . LEU A 1 568 ? 118.408 534.132 70.109 1.00 21.69 ? 622 LEU A CG 1 ATOM 4196 C CD1 . LEU A 1 568 ? 119.156 535.194 69.377 1.00 21.31 ? 622 LEU A CD1 1 ATOM 4197 C CD2 . LEU A 1 568 ? 117.573 533.284 69.169 1.00 22.62 ? 622 LEU A CD2 1 ATOM 4198 N N . SER A 1 569 ? 118.753 535.923 73.013 1.00 20.50 ? 623 SER A N 1 ATOM 4199 C CA . SER A 1 569 ? 117.762 536.620 73.825 1.00 19.71 ? 623 SER A CA 1 ATOM 4200 C C . SER A 1 569 ? 116.807 537.435 72.973 1.00 22.34 ? 623 SER A C 1 ATOM 4201 O O . SER A 1 569 ? 117.255 538.081 72.049 1.00 21.08 ? 623 SER A O 1 ATOM 4202 C CB . SER A 1 569 ? 118.440 537.553 74.816 1.00 21.48 ? 623 SER A CB 1 ATOM 4203 O OG . SER A 1 569 ? 117.473 538.193 75.635 1.00 23.34 ? 623 SER A OG 1 ATOM 4204 N N . ARG A 1 570 ? 115.497 537.453 73.313 1.00 19.97 ? 624 ARG A N 1 ATOM 4205 C CA . ARG A 1 570 ? 114.539 538.292 72.602 1.00 19.94 ? 624 ARG A CA 1 ATOM 4206 C C . ARG A 1 570 ? 114.588 539.748 73.088 1.00 23.23 ? 624 ARG A C 1 ATOM 4207 O O . ARG A 1 570 ? 114.703 540.666 72.291 1.00 21.67 ? 624 ARG A O 1 ATOM 4208 C CB . ARG A 1 570 ? 113.111 537.732 72.722 1.00 21.49 ? 624 ARG A CB 1 ATOM 4209 C CG . ARG A 1 570 ? 112.247 538.199 71.545 1.00 26.94 ? 624 ARG A CG 1 ATOM 4210 C CD . ARG A 1 570 ? 110.961 537.426 71.370 1.00 36.88 ? 624 ARG A CD 1 ATOM 4211 N NE . ARG A 1 570 ? 110.049 537.665 72.486 1.00 39.48 ? 624 ARG A NE 1 ATOM 4212 C CZ . ARG A 1 570 ? 108.793 537.241 72.537 1.00 45.48 ? 624 ARG A CZ 1 ATOM 4213 N NH1 . ARG A 1 570 ? 108.300 536.489 71.565 1.00 32.17 ? 624 ARG A NH1 1 ATOM 4214 N NH2 . ARG A 1 570 ? 108.024 537.550 73.573 1.00 24.31 ? 624 ARG A NH2 1 ATOM 4215 N N . ALA A 1 571 ? 114.507 539.936 74.410 1.00 21.21 ? 625 ALA A N 1 ATOM 4216 C CA . ALA A 1 571 ? 114.540 541.239 75.041 1.00 20.76 ? 625 ALA A CA 1 ATOM 4217 C C . ALA A 1 571 ? 115.977 541.664 75.330 1.00 23.58 ? 625 ALA A C 1 ATOM 4218 O O . ALA A 1 571 ? 116.882 540.825 75.493 1.00 21.52 ? 625 ALA A O 1 ATOM 4219 C CB . ALA A 1 571 ? 113.718 541.215 76.317 1.00 21.10 ? 625 ALA A CB 1 ATOM 4220 N N . PHE A 1 572 ? 116.191 542.976 75.385 1.00 17.54 ? 626 PHE A N 1 ATOM 4221 C CA . PHE A 1 572 ? 117.535 543.491 75.575 1.00 15.19 ? 626 PHE A CA 1 ATOM 4222 C C . PHE A 1 572 ? 117.491 544.942 75.920 1.00 19.33 ? 626 PHE A C 1 ATOM 4223 O O . PHE A 1 572 ? 116.451 545.598 75.831 1.00 16.91 ? 626 PHE A O 1 ATOM 4224 C CB . PHE A 1 572 ? 118.393 543.267 74.294 1.00 15.80 ? 626 PHE A CB 1 ATOM 4225 C CG . PHE A 1 572 ? 117.776 543.744 73.002 1.00 15.16 ? 626 PHE A CG 1 ATOM 4226 C CD1 . PHE A 1 572 ? 117.844 545.085 72.626 1.00 18.19 ? 626 PHE A CD1 1 ATOM 4227 C CD2 . PHE A 1 572 ? 117.113 542.865 72.171 1.00 15.66 ? 626 PHE A CD2 1 ATOM 4228 C CE1 . PHE A 1 572 ? 117.265 545.526 71.422 1.00 18.08 ? 626 PHE A CE1 1 ATOM 4229 C CE2 . PHE A 1 572 ? 116.554 543.303 70.963 1.00 17.63 ? 626 PHE A CE2 1 ATOM 4230 C CZ . PHE A 1 572 ? 116.621 544.630 70.605 1.00 15.31 ? 626 PHE A CZ 1 ATOM 4231 N N . PHE A 1 573 ? 118.654 545.434 76.335 1.00 19.18 ? 627 PHE A N 1 ATOM 4232 C CA . PHE A 1 573 ? 118.899 546.810 76.734 1.00 19.13 ? 627 PHE A CA 1 ATOM 4233 C C . PHE A 1 573 ? 120.341 547.155 76.394 1.00 24.40 ? 627 PHE A C 1 ATOM 4234 O O . PHE A 1 573 ? 121.097 546.279 75.931 1.00 23.76 ? 627 PHE A O 1 ATOM 4235 C CB . PHE A 1 573 ? 118.665 546.943 78.257 1.00 20.85 ? 627 PHE A CB 1 ATOM 4236 C CG . PHE A 1 573 ? 118.587 548.372 78.760 1.00 22.77 ? 627 PHE A CG 1 ATOM 4237 C CD1 . PHE A 1 573 ? 117.468 549.155 78.503 1.00 26.87 ? 627 PHE A CD1 1 ATOM 4238 C CD2 . PHE A 1 573 ? 119.629 548.929 79.500 1.00 24.48 ? 627 PHE A CD2 1 ATOM 4239 C CE1 . PHE A 1 573 ? 117.387 550.467 78.980 1.00 28.38 ? 627 PHE A CE1 1 ATOM 4240 C CE2 . PHE A 1 573 ? 119.546 550.235 79.987 1.00 27.39 ? 627 PHE A CE2 1 ATOM 4241 C CZ . PHE A 1 573 ? 118.427 550.998 79.722 1.00 26.70 ? 627 PHE A CZ 1 ATOM 4242 N N . SER A 1 574 ? 120.745 548.430 76.622 1.00 21.67 ? 628 SER A N 1 ATOM 4243 C CA . SER A 1 574 ? 122.157 548.826 76.539 1.00 20.28 ? 628 SER A CA 1 ATOM 4244 C C . SER A 1 574 ? 122.951 547.806 77.421 1.00 24.66 ? 628 SER A C 1 ATOM 4245 O O . SER A 1 574 ? 122.517 547.445 78.529 1.00 23.41 ? 628 SER A O 1 ATOM 4246 C CB . SER A 1 574 ? 122.351 550.209 77.147 1.00 20.06 ? 628 SER A CB 1 ATOM 4247 O OG . SER A 1 574 ? 121.826 551.205 76.292 1.00 30.04 ? 628 SER A OG 1 ATOM 4248 N N . GLY A 1 575 ? 124.080 547.346 76.922 1.00 20.09 ? 629 GLY A N 1 ATOM 4249 C CA . GLY A 1 575 ? 124.868 546.348 77.639 1.00 19.66 ? 629 GLY A CA 1 ATOM 4250 C C . GLY A 1 575 ? 124.589 544.910 77.238 1.00 21.96 ? 629 GLY A C 1 ATOM 4251 O O . GLY A 1 575 ? 125.416 544.043 77.507 1.00 22.07 ? 629 GLY A O 1 ATOM 4252 N N . SER A 1 576 ? 123.454 544.637 76.547 1.00 17.05 ? 630 SER A N 1 ATOM 4253 C CA . SER A 1 576 ? 123.113 543.266 76.128 1.00 16.70 ? 630 SER A CA 1 ATOM 4254 C C . SER A 1 576 ? 124.118 542.637 75.195 1.00 21.90 ? 630 SER A C 1 ATOM 4255 O O . SER A 1 576 ? 124.210 541.390 75.103 1.00 22.82 ? 630 SER A O 1 ATOM 4256 C CB . SER A 1 576 ? 121.729 543.208 75.512 1.00 20.80 ? 630 SER A CB 1 ATOM 4257 O OG . SER A 1 576 ? 120.733 543.303 76.517 1.00 31.70 ? 630 SER A OG 1 ATOM 4258 N N . GLN A 1 577 ? 124.916 543.484 74.512 1.00 15.07 ? 631 GLN A N 1 ATOM 4259 C CA . GLN A 1 577 ? 125.950 542.955 73.629 1.00 12.62 ? 631 GLN A CA 1 ATOM 4260 C C . GLN A 1 577 ? 126.920 542.066 74.368 1.00 17.57 ? 631 GLN A C 1 ATOM 4261 O O . GLN A 1 577 ? 127.522 541.177 73.769 1.00 16.00 ? 631 GLN A O 1 ATOM 4262 C CB . GLN A 1 577 ? 126.670 544.071 72.897 1.00 13.56 ? 631 GLN A CB 1 ATOM 4263 C CG . GLN A 1 577 ? 127.491 545.044 73.742 1.00 17.08 ? 631 GLN A CG 1 ATOM 4264 C CD . GLN A 1 577 ? 126.743 546.223 74.303 1.00 31.34 ? 631 GLN A CD 1 ATOM 4265 O OE1 . GLN A 1 577 ? 125.520 546.225 74.449 1.00 29.63 ? 631 GLN A OE1 1 ATOM 4266 N NE2 . GLN A 1 577 ? 127.475 547.280 74.616 1.00 34.65 ? 631 GLN A NE2 1 ATOM 4267 N N . ARG A 1 578 ? 127.060 542.284 75.694 1.00 17.27 ? 632 ARG A N 1 ATOM 4268 C CA . ARG A 1 578 ? 128.015 541.536 76.511 1.00 16.64 ? 632 ARG A CA 1 ATOM 4269 C C . ARG A 1 578 ? 127.632 540.062 76.732 1.00 21.83 ? 632 ARG A C 1 ATOM 4270 O O . ARG A 1 578 ? 128.456 539.284 77.273 1.00 20.75 ? 632 ARG A O 1 ATOM 4271 C CB . ARG A 1 578 ? 128.203 542.229 77.866 1.00 15.11 ? 632 ARG A CB 1 ATOM 4272 C CG . ARG A 1 578 ? 128.723 543.636 77.781 1.00 19.75 ? 632 ARG A CG 1 ATOM 4273 C CD . ARG A 1 578 ? 129.311 544.098 79.087 1.00 17.86 ? 632 ARG A CD 1 ATOM 4274 N NE . ARG A 1 578 ? 128.483 543.928 80.293 1.00 22.55 ? 632 ARG A NE 1 ATOM 4275 C CZ . ARG A 1 578 ? 127.662 544.845 80.813 1.00 35.11 ? 632 ARG A CZ 1 ATOM 4276 N NH1 . ARG A 1 578 ? 127.030 544.606 81.954 1.00 24.97 ? 632 ARG A NH1 1 ATOM 4277 N NH2 . ARG A 1 578 ? 127.466 546.007 80.192 1.00 17.41 ? 632 ARG A NH2 1 ATOM 4278 N N . PHE A 1 579 ? 126.384 539.674 76.342 1.00 17.91 ? 633 PHE A N 1 ATOM 4279 C CA . PHE A 1 579 ? 125.847 538.364 76.723 1.00 16.88 ? 633 PHE A CA 1 ATOM 4280 C C . PHE A 1 579 ? 125.479 537.414 75.589 1.00 23.23 ? 633 PHE A C 1 ATOM 4281 O O . PHE A 1 579 ? 125.165 536.263 75.859 1.00 25.44 ? 633 PHE A O 1 ATOM 4282 C CB . PHE A 1 579 ? 124.652 538.559 77.682 1.00 17.33 ? 633 PHE A CB 1 ATOM 4283 C CG . PHE A 1 579 ? 124.987 539.498 78.812 1.00 18.88 ? 633 PHE A CG 1 ATOM 4284 C CD1 . PHE A 1 579 ? 126.031 539.212 79.693 1.00 21.19 ? 633 PHE A CD1 1 ATOM 4285 C CD2 . PHE A 1 579 ? 124.343 540.730 78.932 1.00 21.77 ? 633 PHE A CD2 1 ATOM 4286 C CE1 . PHE A 1 579 ? 126.413 540.133 80.672 1.00 21.22 ? 633 PHE A CE1 1 ATOM 4287 C CE2 . PHE A 1 579 ? 124.707 541.635 79.942 1.00 22.20 ? 633 PHE A CE2 1 ATOM 4288 C CZ . PHE A 1 579 ? 125.738 541.329 80.797 1.00 19.33 ? 633 PHE A CZ 1 ATOM 4289 N N . GLY A 1 580 ? 125.622 537.827 74.346 1.00 18.12 ? 634 GLY A N 1 ATOM 4290 C CA . GLY A 1 580 ? 125.334 536.908 73.266 1.00 17.85 ? 634 GLY A CA 1 ATOM 4291 C C . GLY A 1 580 ? 124.636 537.567 72.110 1.00 21.62 ? 634 GLY A C 1 ATOM 4292 O O . GLY A 1 580 ? 125.002 538.678 71.719 1.00 20.86 ? 634 GLY A O 1 ATOM 4293 N N . ALA A 1 581 ? 123.645 536.852 71.553 1.00 16.87 ? 635 ALA A N 1 ATOM 4294 C CA . ALA A 1 581 ? 122.922 537.249 70.364 1.00 16.67 ? 635 ALA A CA 1 ATOM 4295 C C . ALA A 1 581 ? 121.505 537.676 70.680 1.00 21.08 ? 635 ALA A C 1 ATOM 4296 O O . ALA A 1 581 ? 120.971 537.348 71.724 1.00 20.25 ? 635 ALA A O 1 ATOM 4297 C CB . ALA A 1 581 ? 122.903 536.079 69.379 1.00 17.08 ? 635 ALA A CB 1 ATOM 4298 N N . VAL A 1 582 ? 120.898 538.416 69.761 1.00 18.40 ? 636 VAL A N 1 ATOM 4299 C CA . VAL A 1 582 ? 119.498 538.829 69.817 1.00 16.45 ? 636 VAL A CA 1 ATOM 4300 C C . VAL A 1 582 ? 118.924 538.616 68.402 1.00 21.92 ? 636 VAL A C 1 ATOM 4301 O O . VAL A 1 582 ? 119.673 538.566 67.423 1.00 18.88 ? 636 VAL A O 1 ATOM 4302 C CB . VAL A 1 582 ? 119.310 540.304 70.300 1.00 17.71 ? 636 VAL A CB 1 ATOM 4303 C CG1 . VAL A 1 582 ? 119.860 540.523 71.714 1.00 17.10 ? 636 VAL A CG1 1 ATOM 4304 C CG2 . VAL A 1 582 ? 119.944 541.288 69.341 1.00 16.23 ? 636 VAL A CG2 1 ATOM 4305 N N . TRP A 1 583 ? 117.601 538.505 68.299 1.00 21.47 ? 637 TRP A N 1 ATOM 4306 C CA . TRP A 1 583 ? 116.948 538.439 67.006 1.00 20.90 ? 637 TRP A CA 1 ATOM 4307 C C . TRP A 1 583 ? 115.709 539.330 67.017 1.00 25.31 ? 637 TRP A C 1 ATOM 4308 O O . TRP A 1 583 ? 115.252 539.739 68.089 1.00 24.70 ? 637 TRP A O 1 ATOM 4309 C CB . TRP A 1 583 ? 116.703 536.997 66.546 1.00 19.73 ? 637 TRP A CB 1 ATOM 4310 C CG . TRP A 1 583 ? 115.370 536.437 66.896 1.00 21.04 ? 637 TRP A CG 1 ATOM 4311 C CD1 . TRP A 1 583 ? 114.340 536.208 66.039 1.00 23.71 ? 637 TRP A CD1 1 ATOM 4312 C CD2 . TRP A 1 583 ? 114.890 536.077 68.212 1.00 21.36 ? 637 TRP A CD2 1 ATOM 4313 N NE1 . TRP A 1 583 ? 113.268 535.669 66.720 1.00 24.20 ? 637 TRP A NE1 1 ATOM 4314 C CE2 . TRP A 1 583 ? 113.581 535.567 68.053 1.00 25.48 ? 637 TRP A CE2 1 ATOM 4315 C CE3 . TRP A 1 583 ? 115.444 536.121 69.506 1.00 22.41 ? 637 TRP A CE3 1 ATOM 4316 C CZ2 . TRP A 1 583 ? 112.826 535.070 69.129 1.00 24.11 ? 637 TRP A CZ2 1 ATOM 4317 C CZ3 . TRP A 1 583 ? 114.706 535.606 70.569 1.00 24.00 ? 637 TRP A CZ3 1 ATOM 4318 C CH2 . TRP A 1 583 ? 113.403 535.113 70.377 1.00 24.85 ? 637 TRP A CH2 1 ATOM 4319 N N . THR A 1 584 ? 115.182 539.653 65.834 1.00 22.25 ? 638 THR A N 1 ATOM 4320 C CA . THR A 1 584 ? 114.079 540.599 65.686 1.00 22.03 ? 638 THR A CA 1 ATOM 4321 C C . THR A 1 584 ? 112.702 540.030 65.975 1.00 26.67 ? 638 THR A C 1 ATOM 4322 O O . THR A 1 584 ? 111.689 540.638 65.616 1.00 28.89 ? 638 THR A O 1 ATOM 4323 C CB . THR A 1 584 ? 114.123 541.286 64.325 1.00 25.31 ? 638 THR A CB 1 ATOM 4324 O OG1 . THR A 1 584 ? 114.050 540.295 63.294 1.00 27.15 ? 638 THR A OG1 1 ATOM 4325 C CG2 . THR A 1 584 ? 115.353 542.142 64.148 1.00 18.64 ? 638 THR A CG2 1 ATOM 4326 N N . GLY A 1 585 ? 112.657 538.915 66.666 1.00 22.82 ? 639 GLY A N 1 ATOM 4327 C CA . GLY A 1 585 ? 111.398 538.327 67.101 1.00 22.98 ? 639 GLY A CA 1 ATOM 4328 C C . GLY A 1 585 ? 110.505 537.715 66.045 1.00 29.86 ? 639 GLY A C 1 ATOM 4329 O O . GLY A 1 585 ? 110.976 537.139 65.061 1.00 29.34 ? 639 GLY A O 1 ATOM 4330 N N . ASP A 1 586 ? 109.193 537.826 66.259 1.00 27.93 ? 640 ASP A N 1 ATOM 4331 C CA . ASP A 1 586 ? 108.227 537.131 65.420 1.00 27.07 ? 640 ASP A CA 1 ATOM 4332 C C . ASP A 1 586 ? 107.849 537.927 64.205 1.00 30.58 ? 640 ASP A C 1 ATOM 4333 O O . ASP A 1 586 ? 106.854 538.655 64.185 1.00 32.00 ? 640 ASP A O 1 ATOM 4334 C CB . ASP A 1 586 ? 107.017 536.692 66.251 1.00 28.43 ? 640 ASP A CB 1 ATOM 4335 C CG . ASP A 1 586 ? 107.367 535.795 67.422 1.00 34.38 ? 640 ASP A CG 1 ATOM 4336 O OD1 . ASP A 1 586 ? 108.395 535.082 67.346 1.00 32.40 ? 640 ASP A OD1 1 ATOM 4337 O OD2 . ASP A 1 586 ? 106.640 535.838 68.432 1.00 41.70 ? 640 ASP A OD2 1 ATOM 4338 N N . ASN A 1 587 ? 108.686 537.810 63.193 1.00 25.68 ? 641 ASN A N 1 ATOM 4339 C CA . ASN A 1 587 ? 108.458 538.443 61.906 1.00 25.32 ? 641 ASN A CA 1 ATOM 4340 C C . ASN A 1 587 ? 107.493 537.556 61.068 1.00 29.53 ? 641 ASN A C 1 ATOM 4341 O O . ASN A 1 587 ? 107.006 536.528 61.531 1.00 29.33 ? 641 ASN A O 1 ATOM 4342 C CB . ASN A 1 587 ? 109.788 538.701 61.160 1.00 20.79 ? 641 ASN A CB 1 ATOM 4343 C CG . ASN A 1 587 ? 110.573 537.450 60.851 1.00 22.71 ? 641 ASN A CG 1 ATOM 4344 O OD1 . ASN A 1 587 ? 110.283 536.360 61.340 1.00 11.75 ? 641 ASN A OD1 1 ATOM 4345 N ND2 . ASN A 1 587 ? 111.627 537.603 60.067 1.00 10.85 ? 641 ASN A ND2 1 ATOM 4346 N N . THR A 1 588 ? 107.253 537.948 59.833 1.00 26.36 ? 642 THR A N 1 ATOM 4347 C CA . THR A 1 588 ? 106.325 537.258 58.951 1.00 26.53 ? 642 THR A CA 1 ATOM 4348 C C . THR A 1 588 ? 107.005 536.904 57.628 1.00 29.59 ? 642 THR A C 1 ATOM 4349 O O . THR A 1 588 ? 107.874 537.632 57.152 1.00 27.81 ? 642 THR A O 1 ATOM 4350 C CB . THR A 1 588 ? 105.055 538.146 58.762 1.00 29.64 ? 642 THR A CB 1 ATOM 4351 O OG1 . THR A 1 588 ? 104.475 538.358 60.042 1.00 30.67 ? 642 THR A OG1 1 ATOM 4352 C CG2 . THR A 1 588 ? 104.014 537.516 57.878 1.00 23.71 ? 642 THR A CG2 1 ATOM 4353 N N . ALA A 1 589 ? 106.566 535.795 57.036 1.00 27.31 ? 643 ALA A N 1 ATOM 4354 C CA . ALA A 1 589 ? 107.045 535.282 55.770 1.00 26.91 ? 643 ALA A CA 1 ATOM 4355 C C . ALA A 1 589 ? 106.546 536.128 54.587 1.00 30.68 ? 643 ALA A C 1 ATOM 4356 O O . ALA A 1 589 ? 105.739 535.657 53.779 1.00 30.69 ? 643 ALA A O 1 ATOM 4357 C CB . ALA A 1 589 ? 106.636 533.826 55.638 1.00 27.37 ? 643 ALA A CB 1 ATOM 4358 N N . GLU A 1 590 ? 107.047 537.381 54.489 1.00 26.74 ? 644 GLU A N 1 ATOM 4359 C CA . GLU A 1 590 ? 106.675 538.353 53.454 1.00 27.05 ? 644 GLU A CA 1 ATOM 4360 C C . GLU A 1 590 ? 107.904 539.128 53.004 1.00 33.62 ? 644 GLU A C 1 ATOM 4361 O O . GLU A 1 590 ? 108.815 539.375 53.804 1.00 34.13 ? 644 GLU A O 1 ATOM 4362 C CB . GLU A 1 590 ? 105.614 539.355 53.970 1.00 28.60 ? 644 GLU A CB 1 ATOM 4363 C CG . GLU A 1 590 ? 104.162 538.874 54.036 1.00 43.75 ? 644 GLU A CG 1 ATOM 4364 C CD . GLU A 1 590 ? 103.207 539.736 54.866 1.00 71.49 ? 644 GLU A CD 1 ATOM 4365 O OE1 . GLU A 1 590 ? 103.556 540.893 55.214 1.00 71.83 ? 644 GLU A OE1 1 ATOM 4366 O OE2 . GLU A 1 590 ? 102.099 539.241 55.176 1.00 59.04 ? 644 GLU A OE2 1 ATOM 4367 N N . TRP A 1 591 ? 107.898 539.573 51.740 1.00 30.64 ? 645 TRP A N 1 ATOM 4368 C CA . TRP A 1 591 ? 109.007 540.308 51.145 1.00 30.11 ? 645 TRP A CA 1 ATOM 4369 C C . TRP A 1 591 ? 109.399 541.549 51.913 1.00 32.74 ? 645 TRP A C 1 ATOM 4370 O O . TRP A 1 591 ? 110.596 541.810 52.076 1.00 33.02 ? 645 TRP A O 1 ATOM 4371 C CB . TRP A 1 591 ? 108.702 540.648 49.670 1.00 29.06 ? 645 TRP A CB 1 ATOM 4372 C CG . TRP A 1 591 ? 108.721 539.446 48.782 1.00 29.53 ? 645 TRP A CG 1 ATOM 4373 C CD1 . TRP A 1 591 ? 107.669 538.635 48.474 1.00 32.25 ? 645 TRP A CD1 1 ATOM 4374 C CD2 . TRP A 1 591 ? 109.879 538.828 48.216 1.00 29.05 ? 645 TRP A CD2 1 ATOM 4375 N NE1 . TRP A 1 591 ? 108.097 537.569 47.720 1.00 30.33 ? 645 TRP A NE1 1 ATOM 4376 C CE2 . TRP A 1 591 ? 109.446 537.666 47.538 1.00 31.59 ? 645 TRP A CE2 1 ATOM 4377 C CE3 . TRP A 1 591 ? 111.258 539.112 48.260 1.00 29.88 ? 645 TRP A CE3 1 ATOM 4378 C CZ2 . TRP A 1 591 ? 110.332 536.827 46.853 1.00 30.71 ? 645 TRP A CZ2 1 ATOM 4379 C CZ3 . TRP A 1 591 ? 112.134 538.281 47.573 1.00 30.79 ? 645 TRP A CZ3 1 ATOM 4380 C CH2 . TRP A 1 591 ? 111.671 537.151 46.884 1.00 30.92 ? 645 TRP A CH2 1 ATOM 4381 N N . ASP A 1 592 ? 108.413 542.315 52.391 1.00 28.03 ? 646 ASP A N 1 ATOM 4382 C CA A ASP A 1 592 ? 108.734 543.539 53.118 0.50 27.32 ? 646 ASP A CA 1 ATOM 4383 C CA B ASP A 1 592 ? 108.681 543.543 53.136 0.50 27.08 ? 646 ASP A CA 1 ATOM 4384 C C . ASP A 1 592 ? 109.395 543.249 54.489 1.00 29.58 ? 646 ASP A C 1 ATOM 4385 O O . ASP A 1 592 ? 110.194 544.053 54.947 1.00 26.81 ? 646 ASP A O 1 ATOM 4386 C CB A ASP A 1 592 ? 107.519 544.476 53.209 0.50 28.86 ? 646 ASP A CB 1 ATOM 4387 C CB B ASP A 1 592 ? 107.401 544.411 53.276 0.50 28.27 ? 646 ASP A CB 1 ATOM 4388 C CG A ASP A 1 592 ? 107.248 545.267 51.939 0.50 39.30 ? 646 ASP A CG 1 ATOM 4389 C CG B ASP A 1 592 ? 106.163 543.771 53.904 0.50 35.24 ? 646 ASP A CG 1 ATOM 4390 O OD1 A ASP A 1 592 ? 108.142 545.320 51.063 0.50 38.11 ? 646 ASP A OD1 1 ATOM 4391 O OD1 B ASP A 1 592 ? 106.073 542.521 53.916 0.50 35.35 ? 646 ASP A OD1 1 ATOM 4392 O OD2 A ASP A 1 592 ? 106.141 545.840 51.822 0.50 50.08 ? 646 ASP A OD2 1 ATOM 4393 O OD2 B ASP A 1 592 ? 105.264 544.527 54.349 0.50 38.33 ? 646 ASP A OD2 1 ATOM 4394 N N . HIS A 1 593 ? 109.149 542.070 55.101 1.00 27.31 ? 647 HIS A N 1 ATOM 4395 C CA . HIS A 1 593 ? 109.829 541.723 56.347 1.00 26.86 ? 647 HIS A CA 1 ATOM 4396 C C . HIS A 1 593 ? 111.232 541.292 56.018 1.00 30.79 ? 647 HIS A C 1 ATOM 4397 O O . HIS A 1 593 ? 112.143 541.566 56.800 1.00 30.94 ? 647 HIS A O 1 ATOM 4398 C CB . HIS A 1 593 ? 109.106 540.621 57.100 1.00 28.03 ? 647 HIS A CB 1 ATOM 4399 C CG . HIS A 1 593 ? 107.890 541.084 57.843 1.00 31.56 ? 647 HIS A CG 1 ATOM 4400 N ND1 . HIS A 1 593 ? 107.847 541.097 59.228 1.00 32.73 ? 647 HIS A ND1 1 ATOM 4401 C CD2 . HIS A 1 593 ? 106.703 541.525 57.370 1.00 33.76 ? 647 HIS A CD2 1 ATOM 4402 C CE1 . HIS A 1 593 ? 106.647 541.546 59.552 1.00 32.57 ? 647 HIS A CE1 1 ATOM 4403 N NE2 . HIS A 1 593 ? 105.923 541.817 58.467 1.00 33.38 ? 647 HIS A NE2 1 ATOM 4404 N N . LEU A 1 594 ? 111.434 540.633 54.856 1.00 27.37 ? 648 LEU A N 1 ATOM 4405 C CA . LEU A 1 594 ? 112.793 540.317 54.404 1.00 25.93 ? 648 LEU A CA 1 ATOM 4406 C C . LEU A 1 594 ? 113.587 541.602 54.258 1.00 29.97 ? 648 LEU A C 1 ATOM 4407 O O . LEU A 1 594 ? 114.700 541.688 54.774 1.00 31.37 ? 648 LEU A O 1 ATOM 4408 C CB . LEU A 1 594 ? 112.802 539.558 53.083 1.00 25.30 ? 648 LEU A CB 1 ATOM 4409 C CG . LEU A 1 594 ? 114.183 539.381 52.423 1.00 27.37 ? 648 LEU A CG 1 ATOM 4410 C CD1 . LEU A 1 594 ? 115.059 538.550 53.252 1.00 27.30 ? 648 LEU A CD1 1 ATOM 4411 C CD2 . LEU A 1 594 ? 114.050 538.736 51.083 1.00 24.39 ? 648 LEU A CD2 1 ATOM 4412 N N . LYS A 1 595 ? 112.984 542.624 53.653 1.00 25.17 ? 649 LYS A N 1 ATOM 4413 C CA . LYS A 1 595 ? 113.658 543.893 53.481 1.00 24.68 ? 649 LYS A CA 1 ATOM 4414 C C . LYS A 1 595 ? 114.031 544.511 54.801 1.00 27.22 ? 649 LYS A C 1 ATOM 4415 O O . LYS A 1 595 ? 115.160 544.989 54.940 1.00 27.14 ? 649 LYS A O 1 ATOM 4416 C CB . LYS A 1 595 ? 112.792 544.881 52.696 1.00 26.63 ? 649 LYS A CB 1 ATOM 4417 C CG . LYS A 1 595 ? 112.647 544.516 51.230 1.00 28.36 ? 649 LYS A CG 1 ATOM 4418 C CD . LYS A 1 595 ? 111.629 545.409 50.539 1.00 30.76 ? 649 LYS A CD 1 ATOM 4419 C CE . LYS A 1 595 ? 111.436 545.065 49.074 1.00 28.35 ? 649 LYS A CE 1 ATOM 4420 N NZ . LYS A 1 595 ? 112.703 545.206 48.262 1.00 26.12 ? 649 LYS A NZ 1 ATOM 4421 N N . ILE A 1 596 ? 113.087 544.522 55.764 1.00 21.24 ? 650 ILE A N 1 ATOM 4422 C CA . ILE A 1 596 ? 113.283 545.252 56.998 1.00 19.38 ? 650 ILE A CA 1 ATOM 4423 C C . ILE A 1 596 ? 114.358 544.650 57.902 1.00 23.35 ? 650 ILE A C 1 ATOM 4424 O O . ILE A 1 596 ? 114.812 545.329 58.812 1.00 24.62 ? 650 ILE A O 1 ATOM 4425 C CB . ILE A 1 596 ? 111.973 545.528 57.739 1.00 20.91 ? 650 ILE A CB 1 ATOM 4426 C CG1 . ILE A 1 596 ? 112.033 546.951 58.350 1.00 19.86 ? 650 ILE A CG1 1 ATOM 4427 C CG2 . ILE A 1 596 ? 111.614 544.404 58.737 1.00 21.27 ? 650 ILE A CG2 1 ATOM 4428 C CD1 . ILE A 1 596 ? 110.766 547.568 58.670 1.00 26.96 ? 650 ILE A CD1 1 ATOM 4429 N N . SER A 1 597 ? 114.775 543.423 57.648 1.00 20.59 ? 651 SER A N 1 ATOM 4430 C CA . SER A 1 597 ? 115.830 542.790 58.425 1.00 21.34 ? 651 SER A CA 1 ATOM 4431 C C . SER A 1 597 ? 117.123 543.638 58.386 1.00 26.42 ? 651 SER A C 1 ATOM 4432 O O . SER A 1 597 ? 117.829 543.713 59.398 1.00 25.12 ? 651 SER A O 1 ATOM 4433 C CB . SER A 1 597 ? 116.073 541.349 57.963 1.00 25.10 ? 651 SER A CB 1 ATOM 4434 O OG . SER A 1 597 ? 116.689 541.231 56.690 1.00 35.98 ? 651 SER A OG 1 ATOM 4435 N N . ILE A 1 598 ? 117.389 544.336 57.252 1.00 23.64 ? 652 ILE A N 1 ATOM 4436 C CA . ILE A 1 598 ? 118.593 545.160 57.148 1.00 23.63 ? 652 ILE A CA 1 ATOM 4437 C C . ILE A 1 598 ? 118.523 546.358 58.060 1.00 26.80 ? 652 ILE A C 1 ATOM 4438 O O . ILE A 1 598 ? 119.382 546.431 58.948 1.00 26.09 ? 652 ILE A O 1 ATOM 4439 C CB . ILE A 1 598 ? 118.963 545.536 55.699 1.00 26.61 ? 652 ILE A CB 1 ATOM 4440 C CG1 . ILE A 1 598 ? 119.231 544.284 54.878 1.00 25.68 ? 652 ILE A CG1 1 ATOM 4441 C CG2 . ILE A 1 598 ? 120.152 546.496 55.685 1.00 26.84 ? 652 ILE A CG2 1 ATOM 4442 C CD1 . ILE A 1 598 ? 119.365 544.524 53.431 1.00 26.00 ? 652 ILE A CD1 1 ATOM 4443 N N . PRO A 1 599 ? 117.533 547.286 57.903 1.00 23.34 ? 653 PRO A N 1 ATOM 4444 C CA . PRO A 1 599 ? 117.477 548.426 58.828 1.00 22.93 ? 653 PRO A CA 1 ATOM 4445 C C . PRO A 1 599 ? 117.334 548.047 60.305 1.00 27.47 ? 653 PRO A C 1 ATOM 4446 O O . PRO A 1 599 ? 117.885 548.757 61.129 1.00 28.24 ? 653 PRO A O 1 ATOM 4447 C CB . PRO A 1 599 ? 116.298 549.256 58.315 1.00 24.82 ? 653 PRO A CB 1 ATOM 4448 C CG . PRO A 1 599 ? 115.476 548.330 57.504 1.00 28.63 ? 653 PRO A CG 1 ATOM 4449 C CD . PRO A 1 599 ? 116.468 547.393 56.878 1.00 24.95 ? 653 PRO A CD 1 ATOM 4450 N N . MET A 1 600 ? 116.643 546.938 60.653 1.00 21.99 ? 654 MET A N 1 ATOM 4451 C CA . MET A 1 600 ? 116.514 546.545 62.043 1.00 19.22 ? 654 MET A CA 1 ATOM 4452 C C . MET A 1 600 ? 117.850 546.112 62.621 1.00 24.63 ? 654 MET A C 1 ATOM 4453 O O . MET A 1 600 ? 118.228 546.592 63.676 1.00 23.79 ? 654 MET A O 1 ATOM 4454 C CB . MET A 1 600 ? 115.446 545.473 62.187 1.00 20.73 ? 654 MET A CB 1 ATOM 4455 C CG . MET A 1 600 ? 114.053 546.016 61.964 1.00 22.58 ? 654 MET A CG 1 ATOM 4456 S SD . MET A 1 600 ? 112.747 544.815 62.272 1.00 25.04 ? 654 MET A SD 1 ATOM 4457 C CE . MET A 1 600 ? 112.677 544.882 64.049 1.00 20.93 ? 654 MET A CE 1 ATOM 4458 N N . CYS A 1 601 ? 118.606 545.266 61.909 1.00 25.49 ? 655 CYS A N 1 ATOM 4459 C CA . CYS A 1 601 ? 119.911 544.825 62.414 1.00 25.62 ? 655 CYS A CA 1 ATOM 4460 C C . CYS A 1 601 ? 120.966 545.910 62.340 1.00 27.09 ? 655 CYS A C 1 ATOM 4461 O O . CYS A 1 601 ? 121.850 545.921 63.193 1.00 27.27 ? 655 CYS A O 1 ATOM 4462 C CB . CYS A 1 601 ? 120.381 543.511 61.789 1.00 26.44 ? 655 CYS A CB 1 ATOM 4463 S SG . CYS A 1 601 ? 119.590 542.059 62.514 1.00 30.44 ? 655 CYS A SG 1 ATOM 4464 N N . LEU A 1 602 ? 120.852 546.852 61.403 1.00 22.80 ? 656 LEU A N 1 ATOM 4465 C CA . LEU A 1 602 ? 121.776 547.997 61.341 1.00 22.13 ? 656 LEU A CA 1 ATOM 4466 C C . LEU A 1 602 ? 121.531 548.946 62.514 1.00 24.78 ? 656 LEU A C 1 ATOM 4467 O O . LEU A 1 602 ? 122.503 549.463 63.066 1.00 25.22 ? 656 LEU A O 1 ATOM 4468 C CB . LEU A 1 602 ? 121.650 548.779 60.027 1.00 21.05 ? 656 LEU A CB 1 ATOM 4469 C CG . LEU A 1 602 ? 122.217 548.073 58.807 1.00 22.40 ? 656 LEU A CG 1 ATOM 4470 C CD1 . LEU A 1 602 ? 122.082 548.937 57.602 1.00 19.40 ? 656 LEU A CD1 1 ATOM 4471 C CD2 . LEU A 1 602 ? 123.667 547.704 59.010 1.00 23.32 ? 656 LEU A CD2 1 ATOM 4472 N N . SER A 1 603 ? 120.249 549.161 62.894 1.00 18.43 ? 657 SER A N 1 ATOM 4473 C CA . SER A 1 603 ? 119.904 550.034 64.021 1.00 17.71 ? 657 SER A CA 1 ATOM 4474 C C . SER A 1 603 ? 120.495 549.432 65.304 1.00 22.73 ? 657 SER A C 1 ATOM 4475 O O . SER A 1 603 ? 120.978 550.189 66.163 1.00 21.71 ? 657 SER A O 1 ATOM 4476 C CB . SER A 1 603 ? 118.400 550.270 64.138 1.00 17.18 ? 657 SER A CB 1 ATOM 4477 O OG . SER A 1 603 ? 117.764 549.068 64.539 1.00 33.02 ? 657 SER A OG 1 ATOM 4478 N N . LEU A 1 604 ? 120.501 548.074 65.400 1.00 17.81 ? 658 LEU A N 1 ATOM 4479 C CA . LEU A 1 604 ? 121.111 547.344 66.505 1.00 16.92 ? 658 LEU A CA 1 ATOM 4480 C C . LEU A 1 604 ? 122.625 547.438 66.489 1.00 20.30 ? 658 LEU A C 1 ATOM 4481 O O . LEU A 1 604 ? 123.237 547.674 67.519 1.00 20.52 ? 658 LEU A O 1 ATOM 4482 C CB . LEU A 1 604 ? 120.610 545.886 66.520 1.00 16.69 ? 658 LEU A CB 1 ATOM 4483 C CG . LEU A 1 604 ? 119.203 545.801 67.072 1.00 21.15 ? 658 LEU A CG 1 ATOM 4484 C CD1 . LEU A 1 604 ? 118.594 544.489 66.864 1.00 22.52 ? 658 LEU A CD1 1 ATOM 4485 C CD2 . LEU A 1 604 ? 119.229 546.040 68.497 1.00 21.90 ? 658 LEU A CD2 1 ATOM 4486 N N . ALA A 1 605 ? 123.224 547.303 65.317 1.00 18.17 ? 659 ALA A N 1 ATOM 4487 C CA . ALA A 1 605 ? 124.670 547.390 65.160 1.00 18.22 ? 659 ALA A CA 1 ATOM 4488 C C . ALA A 1 605 ? 125.197 548.721 65.589 1.00 25.62 ? 659 ALA A C 1 ATOM 4489 O O . ALA A 1 605 ? 126.228 548.770 66.238 1.00 26.12 ? 659 ALA A O 1 ATOM 4490 C CB . ALA A 1 605 ? 125.051 547.142 63.723 1.00 18.94 ? 659 ALA A CB 1 ATOM 4491 N N . LEU A 1 606 ? 124.495 549.812 65.239 1.00 23.33 ? 660 LEU A N 1 ATOM 4492 C CA . LEU A 1 606 ? 124.925 551.159 65.580 1.00 22.81 ? 660 LEU A CA 1 ATOM 4493 C C . LEU A 1 606 ? 125.006 551.400 67.071 1.00 27.80 ? 660 LEU A C 1 ATOM 4494 O O . LEU A 1 606 ? 125.839 552.193 67.528 1.00 26.92 ? 660 LEU A O 1 ATOM 4495 C CB . LEU A 1 606 ? 124.007 552.184 64.925 1.00 22.53 ? 660 LEU A CB 1 ATOM 4496 C CG . LEU A 1 606 ? 124.155 552.350 63.413 1.00 26.80 ? 660 LEU A CG 1 ATOM 4497 C CD1 . LEU A 1 606 ? 123.146 553.338 62.882 1.00 25.62 ? 660 LEU A CD1 1 ATOM 4498 C CD2 . LEU A 1 606 ? 125.574 552.785 63.034 1.00 28.38 ? 660 LEU A CD2 1 ATOM 4499 N N . VAL A 1 607 ? 124.168 550.691 67.830 1.00 24.46 ? 661 VAL A N 1 ATOM 4500 C CA . VAL A 1 607 ? 124.111 550.846 69.285 1.00 23.07 ? 661 VAL A CA 1 ATOM 4501 C C . VAL A 1 607 ? 124.782 549.682 70.064 1.00 24.05 ? 661 VAL A C 1 ATOM 4502 O O . VAL A 1 607 ? 124.518 549.488 71.239 1.00 23.90 ? 661 VAL A O 1 ATOM 4503 C CB . VAL A 1 607 ? 122.669 551.129 69.739 1.00 25.46 ? 661 VAL A CB 1 ATOM 4504 C CG1 . VAL A 1 607 ? 122.146 552.352 69.019 1.00 24.57 ? 661 VAL A CG1 1 ATOM 4505 C CG2 . VAL A 1 607 ? 121.756 549.944 69.485 1.00 24.85 ? 661 VAL A CG2 1 ATOM 4506 N N . GLY A 1 608 ? 125.694 548.988 69.406 1.00 18.62 ? 662 GLY A N 1 ATOM 4507 C CA . GLY A 1 608 ? 126.557 547.987 70.022 1.00 18.23 ? 662 GLY A CA 1 ATOM 4508 C C . GLY A 1 608 ? 126.162 546.529 69.928 1.00 22.72 ? 662 GLY A C 1 ATOM 4509 O O . GLY A 1 608 ? 126.974 545.663 70.249 1.00 21.94 ? 662 GLY A O 1 ATOM 4510 N N . LEU A 1 609 ? 124.948 546.247 69.453 1.00 19.75 ? 663 LEU A N 1 ATOM 4511 C CA . LEU A 1 609 ? 124.416 544.898 69.337 1.00 19.53 ? 663 LEU A CA 1 ATOM 4512 C C . LEU A 1 609 ? 124.696 544.325 67.954 1.00 26.17 ? 663 LEU A C 1 ATOM 4513 O O . LEU A 1 609 ? 123.847 544.332 67.057 1.00 26.99 ? 663 LEU A O 1 ATOM 4514 C CB . LEU A 1 609 ? 122.933 544.860 69.735 1.00 18.35 ? 663 LEU A CB 1 ATOM 4515 C CG . LEU A 1 609 ? 122.682 544.749 71.230 1.00 21.84 ? 663 LEU A CG 1 ATOM 4516 C CD1 . LEU A 1 609 ? 123.098 546.009 71.980 1.00 21.51 ? 663 LEU A CD1 1 ATOM 4517 C CD2 . LEU A 1 609 ? 121.232 544.476 71.504 1.00 24.81 ? 663 LEU A CD2 1 ATOM 4518 N N . SER A 1 610 ? 125.920 543.836 67.806 1.00 23.12 ? 664 SER A N 1 ATOM 4519 C CA . SER A 1 610 ? 126.458 543.306 66.560 1.00 23.01 ? 664 SER A CA 1 ATOM 4520 C C . SER A 1 610 ? 125.928 541.937 66.198 1.00 26.44 ? 664 SER A C 1 ATOM 4521 O O . SER A 1 610 ? 126.053 541.542 65.047 1.00 26.58 ? 664 SER A O 1 ATOM 4522 C CB . SER A 1 610 ? 127.991 543.259 66.619 1.00 22.21 ? 664 SER A CB 1 ATOM 4523 O OG . SER A 1 610 ? 128.542 544.469 66.154 1.00 24.91 ? 664 SER A OG 1 ATOM 4524 N N . PHE A 1 611 ? 125.441 541.173 67.167 1.00 22.38 ? 665 PHE A N 1 ATOM 4525 C CA . PHE A 1 611 ? 125.039 539.789 66.907 1.00 22.02 ? 665 PHE A CA 1 ATOM 4526 C C . PHE A 1 611 ? 123.529 539.700 66.797 1.00 26.72 ? 665 PHE A C 1 ATOM 4527 O O . PHE A 1 611 ? 122.838 539.226 67.692 1.00 26.77 ? 665 PHE A O 1 ATOM 4528 C CB . PHE A 1 611 ? 125.626 538.922 68.006 1.00 22.89 ? 665 PHE A CB 1 ATOM 4529 C CG . PHE A 1 611 ? 125.833 537.460 67.735 1.00 23.27 ? 665 PHE A CG 1 ATOM 4530 C CD1 . PHE A 1 611 ? 125.518 536.902 66.495 1.00 23.95 ? 665 PHE A CD1 1 ATOM 4531 C CD2 . PHE A 1 611 ? 126.377 536.637 68.708 1.00 24.79 ? 665 PHE A CD2 1 ATOM 4532 C CE1 . PHE A 1 611 ? 125.674 535.529 66.270 1.00 23.28 ? 665 PHE A CE1 1 ATOM 4533 C CE2 . PHE A 1 611 ? 126.536 535.263 68.483 1.00 26.24 ? 665 PHE A CE2 1 ATOM 4534 C CZ . PHE A 1 611 ? 126.204 534.723 67.256 1.00 22.73 ? 665 PHE A CZ 1 ATOM 4535 N N . CYS A 1 612 ? 123.046 540.180 65.677 1.00 25.41 ? 666 CYS A N 1 ATOM 4536 C CA . CYS A 1 612 ? 121.651 540.371 65.337 1.00 25.01 ? 666 CYS A CA 1 ATOM 4537 C C . CYS A 1 612 ? 121.290 539.517 64.146 1.00 24.73 ? 666 CYS A C 1 ATOM 4538 O O . CYS A 1 612 ? 122.119 539.301 63.270 1.00 23.50 ? 666 CYS A O 1 ATOM 4539 C CB . CYS A 1 612 ? 121.431 541.850 65.012 1.00 25.94 ? 666 CYS A CB 1 ATOM 4540 S SG . CYS A 1 612 ? 119.733 542.280 64.549 1.00 30.47 ? 666 CYS A SG 1 ATOM 4541 N N . GLY A 1 613 ? 120.034 539.102 64.093 1.00 16.62 ? 667 GLY A N 1 ATOM 4542 C CA . GLY A 1 613 ? 119.486 538.425 62.945 1.00 15.25 ? 667 GLY A CA 1 ATOM 4543 C C . GLY A 1 613 ? 117.986 538.465 62.956 1.00 20.44 ? 667 GLY A C 1 ATOM 4544 O O . GLY A 1 613 ? 117.369 538.943 63.907 1.00 20.28 ? 667 GLY A O 1 ATOM 4545 N N . ALA A 1 614 ? 117.390 537.955 61.901 1.00 20.56 ? 668 ALA A N 1 ATOM 4546 C CA . ALA A 1 614 ? 115.933 537.817 61.784 1.00 21.43 ? 668 ALA A CA 1 ATOM 4547 C C . ALA A 1 614 ? 115.660 536.390 61.320 1.00 26.77 ? 668 ALA A C 1 ATOM 4548 O O . ALA A 1 614 ? 116.492 535.831 60.613 1.00 27.06 ? 668 ALA A O 1 ATOM 4549 C CB . ALA A 1 614 ? 115.375 538.814 60.786 1.00 21.81 ? 668 ALA A CB 1 ATOM 4550 N N . ASP A 1 615 ? 114.541 535.789 61.742 1.00 23.87 ? 669 ASP A N 1 ATOM 4551 C CA . ASP A 1 615 ? 114.191 534.408 61.358 1.00 22.91 ? 669 ASP A CA 1 ATOM 4552 C C . ASP A 1 615 ? 114.155 534.245 59.875 1.00 26.92 ? 669 ASP A C 1 ATOM 4553 O O . ASP A 1 615 ? 113.407 534.932 59.181 1.00 27.39 ? 669 ASP A O 1 ATOM 4554 C CB . ASP A 1 615 ? 112.830 534.020 61.903 1.00 23.48 ? 669 ASP A CB 1 ATOM 4555 C CG . ASP A 1 615 ? 112.755 533.891 63.394 1.00 26.92 ? 669 ASP A CG 1 ATOM 4556 O OD1 . ASP A 1 615 ? 113.818 533.896 64.057 1.00 28.61 ? 669 ASP A OD1 1 ATOM 4557 O OD2 . ASP A 1 615 ? 111.654 533.749 63.897 1.00 29.92 ? 669 ASP A OD2 1 ATOM 4558 N N . VAL A 1 616 ? 114.991 533.353 59.385 1.00 22.75 ? 670 VAL A N 1 ATOM 4559 C CA . VAL A 1 616 ? 115.105 533.117 57.958 1.00 21.92 ? 670 VAL A CA 1 ATOM 4560 C C . VAL A 1 616 ? 113.852 532.358 57.482 1.00 26.76 ? 670 VAL A C 1 ATOM 4561 O O . VAL A 1 616 ? 113.519 531.285 57.990 1.00 25.61 ? 670 VAL A O 1 ATOM 4562 C CB . VAL A 1 616 ? 116.448 532.427 57.612 1.00 23.83 ? 670 VAL A CB 1 ATOM 4563 C CG1 . VAL A 1 616 ? 116.472 531.947 56.161 1.00 23.24 ? 670 VAL A CG1 1 ATOM 4564 C CG2 . VAL A 1 616 ? 117.631 533.345 57.908 1.00 22.79 ? 670 VAL A CG2 1 ATOM 4565 N N . GLY A 1 617 ? 113.176 532.959 56.520 1.00 24.35 ? 671 GLY A N 1 ATOM 4566 C CA . GLY A 1 617 ? 111.926 532.456 55.970 1.00 24.41 ? 671 GLY A CA 1 ATOM 4567 C C . GLY A 1 617 ? 110.740 533.176 56.568 1.00 29.52 ? 671 GLY A C 1 ATOM 4568 O O . GLY A 1 617 ? 109.649 533.114 56.012 1.00 28.70 ? 671 GLY A O 1 ATOM 4569 N N . GLY A 1 618 ? 110.963 533.875 57.686 1.00 27.73 ? 672 GLY A N 1 ATOM 4570 C CA . GLY A 1 618 ? 109.912 534.539 58.447 1.00 27.15 ? 672 GLY A CA 1 ATOM 4571 C C . GLY A 1 618 ? 109.318 533.555 59.436 1.00 29.95 ? 672 GLY A C 1 ATOM 4572 O O . GLY A 1 618 ? 109.219 532.363 59.145 1.00 29.24 ? 672 GLY A O 1 ATOM 4573 N N . PHE A 1 619 ? 108.924 534.044 60.624 1.00 25.39 ? 673 PHE A N 1 ATOM 4574 C CA . PHE A 1 619 ? 108.331 533.199 61.654 1.00 23.85 ? 673 PHE A CA 1 ATOM 4575 C C . PHE A 1 619 ? 106.905 532.770 61.284 1.00 31.40 ? 673 PHE A C 1 ATOM 4576 O O . PHE A 1 619 ? 106.643 531.571 61.166 1.00 33.55 ? 673 PHE A O 1 ATOM 4577 C CB . PHE A 1 619 ? 108.370 533.909 62.999 1.00 23.93 ? 673 PHE A CB 1 ATOM 4578 C CG . PHE A 1 619 ? 107.773 533.153 64.156 1.00 23.54 ? 673 PHE A CG 1 ATOM 4579 C CD1 . PHE A 1 619 ? 108.397 532.019 64.664 1.00 24.63 ? 673 PHE A CD1 1 ATOM 4580 C CD2 . PHE A 1 619 ? 106.618 533.605 64.776 1.00 25.21 ? 673 PHE A CD2 1 ATOM 4581 C CE1 . PHE A 1 619 ? 107.870 531.346 65.754 1.00 24.99 ? 673 PHE A CE1 1 ATOM 4582 C CE2 . PHE A 1 619 ? 106.112 532.955 65.903 1.00 27.04 ? 673 PHE A CE2 1 ATOM 4583 C CZ . PHE A 1 619 ? 106.730 531.819 66.373 1.00 24.38 ? 673 PHE A CZ 1 ATOM 4584 N N . PHE A 1 620 ? 106.010 533.739 61.080 1.00 27.03 ? 674 PHE A N 1 ATOM 4585 C CA . PHE A 1 620 ? 104.611 533.477 60.768 1.00 26.43 ? 674 PHE A CA 1 ATOM 4586 C C . PHE A 1 620 ? 104.416 533.205 59.297 1.00 29.79 ? 674 PHE A C 1 ATOM 4587 O O . PHE A 1 620 ? 105.047 533.854 58.477 1.00 27.28 ? 674 PHE A O 1 ATOM 4588 C CB . PHE A 1 620 ? 103.741 534.685 61.123 1.00 27.90 ? 674 PHE A CB 1 ATOM 4589 C CG . PHE A 1 620 ? 103.659 535.019 62.584 1.00 29.21 ? 674 PHE A CG 1 ATOM 4590 C CD1 . PHE A 1 620 ? 103.077 534.134 63.489 1.00 32.04 ? 674 PHE A CD1 1 ATOM 4591 C CD2 . PHE A 1 620 ? 104.095 536.245 63.051 1.00 30.60 ? 674 PHE A CD2 1 ATOM 4592 C CE1 . PHE A 1 620 ? 103.003 534.445 64.847 1.00 32.27 ? 674 PHE A CE1 1 ATOM 4593 C CE2 . PHE A 1 620 ? 103.981 536.572 64.398 1.00 33.34 ? 674 PHE A CE2 1 ATOM 4594 C CZ . PHE A 1 620 ? 103.437 535.671 65.289 1.00 31.18 ? 674 PHE A CZ 1 ATOM 4595 N N . LYS A 1 621 ? 103.468 532.307 58.964 1.00 27.29 ? 675 LYS A N 1 ATOM 4596 C CA . LYS A 1 621 ? 103.059 531.986 57.590 1.00 26.95 ? 675 LYS A CA 1 ATOM 4597 C C . LYS A 1 621 ? 104.113 531.164 56.775 1.00 32.65 ? 675 LYS A C 1 ATOM 4598 O O . LYS A 1 621 ? 105.214 530.834 57.265 1.00 32.25 ? 675 LYS A O 1 ATOM 4599 C CB . LYS A 1 621 ? 102.612 533.249 56.822 1.00 27.89 ? 675 LYS A CB 1 ATOM 4600 C CG . LYS A 1 621 ? 101.513 534.031 57.506 1.00 46.12 ? 675 LYS A CG 1 ATOM 4601 C CD . LYS A 1 621 ? 101.030 535.171 56.639 1.00 59.73 ? 675 LYS A CD 1 ATOM 4602 C CE . LYS A 1 621 ? 99.857 535.874 57.271 1.00 75.99 ? 675 LYS A CE 1 ATOM 4603 N NZ . LYS A 1 621 ? 99.605 537.195 56.642 1.00 91.25 ? 675 LYS A NZ 1 ATOM 4604 N N . ASN A 1 622 ? 103.715 530.784 55.548 1.00 28.58 ? 676 ASN A N 1 ATOM 4605 C CA . ASN A 1 622 ? 104.526 529.957 54.677 1.00 28.97 ? 676 ASN A CA 1 ATOM 4606 C C . ASN A 1 622 ? 105.125 530.775 53.560 1.00 31.22 ? 676 ASN A C 1 ATOM 4607 O O . ASN A 1 622 ? 104.388 531.391 52.779 1.00 31.53 ? 676 ASN A O 1 ATOM 4608 C CB . ASN A 1 622 ? 103.713 528.788 54.131 1.00 31.03 ? 676 ASN A CB 1 ATOM 4609 C CG . ASN A 1 622 ? 103.114 527.942 55.216 1.00 45.22 ? 676 ASN A CG 1 ATOM 4610 O OD1 . ASN A 1 622 ? 103.829 527.350 56.012 1.00 31.38 ? 676 ASN A OD1 1 ATOM 4611 N ND2 . ASN A 1 622 ? 101.786 527.878 55.277 1.00 41.49 ? 676 ASN A ND2 1 ATOM 4612 N N . PRO A 1 623 ? 106.467 530.856 53.493 1.00 25.89 ? 677 PRO A N 1 ATOM 4613 C CA . PRO A 1 623 ? 107.071 531.627 52.407 1.00 26.33 ? 677 PRO A CA 1 ATOM 4614 C C . PRO A 1 623 ? 107.035 530.846 51.109 1.00 31.68 ? 677 PRO A C 1 ATOM 4615 O O . PRO A 1 623 ? 107.232 529.632 51.106 1.00 30.98 ? 677 PRO A O 1 ATOM 4616 C CB . PRO A 1 623 ? 108.512 531.817 52.871 1.00 27.98 ? 677 PRO A CB 1 ATOM 4617 C CG . PRO A 1 623 ? 108.795 530.569 53.659 1.00 31.70 ? 677 PRO A CG 1 ATOM 4618 C CD . PRO A 1 623 ? 107.493 530.224 54.347 1.00 26.82 ? 677 PRO A CD 1 ATOM 4619 N N . GLU A 1 624 ? 106.849 531.543 50.000 1.00 31.74 ? 678 GLU A N 1 ATOM 4620 C CA . GLU A 1 624 ? 106.960 530.908 48.684 1.00 32.90 ? 678 GLU A CA 1 ATOM 4621 C C . GLU A 1 624 ? 108.463 530.494 48.516 1.00 34.67 ? 678 GLU A C 1 ATOM 4622 O O . GLU A 1 624 ? 109.330 531.131 49.144 1.00 33.54 ? 678 GLU A O 1 ATOM 4623 C CB . GLU A 1 624 ? 106.464 531.847 47.541 1.00 35.09 ? 678 GLU A CB 1 ATOM 4624 C CG . GLU A 1 624 ? 107.224 533.170 47.457 1.00 52.57 ? 678 GLU A CG 1 ATOM 4625 C CD . GLU A 1 624 ? 106.836 534.203 46.403 1.00 80.91 ? 678 GLU A CD 1 ATOM 4626 O OE1 . GLU A 1 624 ? 106.998 533.937 45.184 1.00 64.81 ? 678 GLU A OE1 1 ATOM 4627 O OE2 . GLU A 1 624 ? 106.490 535.336 46.817 1.00 74.94 ? 678 GLU A OE2 1 ATOM 4628 N N . PRO A 1 625 ? 108.770 529.406 47.747 1.00 30.48 ? 679 PRO A N 1 ATOM 4629 C CA . PRO A 1 625 ? 110.174 528.940 47.611 1.00 30.09 ? 679 PRO A CA 1 ATOM 4630 C C . PRO A 1 625 ? 111.190 530.018 47.268 1.00 32.48 ? 679 PRO A C 1 ATOM 4631 O O . PRO A 1 625 ? 112.270 530.054 47.868 1.00 30.57 ? 679 PRO A O 1 ATOM 4632 C CB . PRO A 1 625 ? 110.087 527.887 46.513 1.00 32.04 ? 679 PRO A CB 1 ATOM 4633 C CG . PRO A 1 625 ? 108.699 527.378 46.617 1.00 36.79 ? 679 PRO A CG 1 ATOM 4634 C CD . PRO A 1 625 ? 107.849 528.532 46.998 1.00 31.86 ? 679 PRO A CD 1 ATOM 4635 N N . GLU A 1 626 ? 110.809 530.928 46.347 1.00 28.81 ? 680 GLU A N 1 ATOM 4636 C CA . GLU A 1 626 ? 111.672 532.025 45.921 1.00 28.51 ? 680 GLU A CA 1 ATOM 4637 C C . GLU A 1 626 ? 111.986 532.968 47.082 1.00 32.96 ? 680 GLU A C 1 ATOM 4638 O O . GLU A 1 626 ? 113.114 533.442 47.192 1.00 32.44 ? 680 GLU A O 1 ATOM 4639 C CB . GLU A 1 626 ? 111.057 532.781 44.747 1.00 29.28 ? 680 GLU A CB 1 ATOM 4640 C CG . GLU A 1 626 ? 111.936 533.899 44.237 1.00 32.22 ? 680 GLU A CG 1 ATOM 4641 C CD . GLU A 1 626 ? 111.265 534.791 43.226 1.00 42.09 ? 680 GLU A CD 1 ATOM 4642 O OE1 . GLU A 1 626 ? 110.031 534.686 43.052 1.00 47.06 ? 680 GLU A OE1 1 ATOM 4643 O OE2 . GLU A 1 626 ? 111.961 535.666 42.672 1.00 35.42 ? 680 GLU A OE2 1 ATOM 4644 N N . LEU A 1 627 ? 111.004 533.235 47.940 1.00 29.28 ? 681 LEU A N 1 ATOM 4645 C CA . LEU A 1 627 ? 111.230 534.104 49.086 1.00 27.69 ? 681 LEU A CA 1 ATOM 4646 C C . LEU A 1 627 ? 112.149 533.397 50.063 1.00 30.02 ? 681 LEU A C 1 ATOM 4647 O O . LEU A 1 627 ? 113.071 534.019 50.584 1.00 28.41 ? 681 LEU A O 1 ATOM 4648 C CB . LEU A 1 627 ? 109.917 534.473 49.761 1.00 27.23 ? 681 LEU A CB 1 ATOM 4649 C CG . LEU A 1 627 ? 110.054 535.182 51.123 1.00 31.12 ? 681 LEU A CG 1 ATOM 4650 C CD1 . LEU A 1 627 ? 110.881 536.480 51.027 1.00 29.90 ? 681 LEU A CD1 1 ATOM 4651 C CD2 . LEU A 1 627 ? 108.710 535.449 51.716 1.00 30.00 ? 681 LEU A CD2 1 ATOM 4652 N N . LEU A 1 628 ? 111.931 532.101 50.281 1.00 26.56 ? 682 LEU A N 1 ATOM 4653 C CA . LEU A 1 628 ? 112.791 531.359 51.188 1.00 25.12 ? 682 LEU A CA 1 ATOM 4654 C C . LEU A 1 628 ? 114.245 531.400 50.728 1.00 26.48 ? 682 LEU A C 1 ATOM 4655 O O . LEU A 1 628 ? 115.133 531.619 51.557 1.00 26.01 ? 682 LEU A O 1 ATOM 4656 C CB . LEU A 1 628 ? 112.285 529.934 51.414 1.00 24.86 ? 682 LEU A CB 1 ATOM 4657 C CG . LEU A 1 628 ? 113.048 529.103 52.460 1.00 30.44 ? 682 LEU A CG 1 ATOM 4658 C CD1 . LEU A 1 628 ? 113.090 529.780 53.820 1.00 30.57 ? 682 LEU A CD1 1 ATOM 4659 C CD2 . LEU A 1 628 ? 112.441 527.718 52.617 1.00 33.86 ? 682 LEU A CD2 1 ATOM 4660 N N . VAL A 1 629 ? 114.489 531.239 49.416 1.00 23.09 ? 683 VAL A N 1 ATOM 4661 C CA . VAL A 1 629 ? 115.841 531.306 48.857 1.00 22.10 ? 683 VAL A CA 1 ATOM 4662 C C . VAL A 1 629 ? 116.461 532.669 49.136 1.00 24.54 ? 683 VAL A C 1 ATOM 4663 O O . VAL A 1 629 ? 117.565 532.731 49.680 1.00 24.35 ? 683 VAL A O 1 ATOM 4664 C CB . VAL A 1 629 ? 115.870 530.958 47.354 1.00 26.44 ? 683 VAL A CB 1 ATOM 4665 C CG1 . VAL A 1 629 ? 117.176 531.407 46.701 1.00 25.74 ? 683 VAL A CG1 1 ATOM 4666 C CG2 . VAL A 1 629 ? 115.626 529.466 47.143 1.00 26.42 ? 683 VAL A CG2 1 ATOM 4667 N N . ARG A 1 630 ? 115.750 533.759 48.790 1.00 21.40 ? 684 ARG A N 1 ATOM 4668 C CA . ARG A 1 630 ? 116.257 535.110 49.011 1.00 21.18 ? 684 ARG A CA 1 ATOM 4669 C C . ARG A 1 630 ? 116.531 535.348 50.495 1.00 26.03 ? 684 ARG A C 1 ATOM 4670 O O . ARG A 1 630 ? 117.487 536.037 50.833 1.00 26.19 ? 684 ARG A O 1 ATOM 4671 C CB . ARG A 1 630 ? 115.323 536.174 48.450 1.00 18.30 ? 684 ARG A CB 1 ATOM 4672 C CG . ARG A 1 630 ? 115.127 536.183 46.930 1.00 25.81 ? 684 ARG A CG 1 ATOM 4673 C CD . ARG A 1 630 ? 116.411 535.959 46.187 1.00 22.40 ? 684 ARG A CD 1 ATOM 4674 N NE . ARG A 1 630 ? 116.307 536.145 44.747 1.00 27.00 ? 684 ARG A NE 1 ATOM 4675 C CZ . ARG A 1 630 ? 117.361 536.131 43.933 1.00 44.54 ? 684 ARG A CZ 1 ATOM 4676 N NH1 . ARG A 1 630 ? 118.583 535.916 44.417 1.00 31.66 ? 684 ARG A NH1 1 ATOM 4677 N NH2 . ARG A 1 630 ? 117.210 536.371 42.641 1.00 28.93 ? 684 ARG A NH2 1 ATOM 4678 N N . TRP A 1 631 ? 115.714 534.755 51.368 1.00 23.17 ? 685 TRP A N 1 ATOM 4679 C CA . TRP A 1 631 ? 115.918 534.892 52.800 1.00 22.81 ? 685 TRP A CA 1 ATOM 4680 C C . TRP A 1 631 ? 117.177 534.155 53.275 1.00 25.02 ? 685 TRP A C 1 ATOM 4681 O O . TRP A 1 631 ? 117.909 534.698 54.104 1.00 24.34 ? 685 TRP A O 1 ATOM 4682 C CB . TRP A 1 631 ? 114.683 534.508 53.604 1.00 21.74 ? 685 TRP A CB 1 ATOM 4683 C CG . TRP A 1 631 ? 114.462 535.444 54.751 1.00 23.62 ? 685 TRP A CG 1 ATOM 4684 C CD1 . TRP A 1 631 ? 115.404 535.919 55.619 1.00 26.69 ? 685 TRP A CD1 1 ATOM 4685 C CD2 . TRP A 1 631 ? 113.221 536.046 55.136 1.00 23.74 ? 685 TRP A CD2 1 ATOM 4686 N NE1 . TRP A 1 631 ? 114.828 536.794 56.510 1.00 26.49 ? 685 TRP A NE1 1 ATOM 4687 C CE2 . TRP A 1 631 ? 113.478 536.840 56.280 1.00 27.52 ? 685 TRP A CE2 1 ATOM 4688 C CE3 . TRP A 1 631 ? 111.896 535.924 54.678 1.00 25.00 ? 685 TRP A CE3 1 ATOM 4689 C CZ2 . TRP A 1 631 ? 112.482 537.588 56.907 1.00 26.26 ? 685 TRP A CZ2 1 ATOM 4690 C CZ3 . TRP A 1 631 ? 110.907 536.666 55.303 1.00 26.39 ? 685 TRP A CZ3 1 ATOM 4691 C CH2 . TRP A 1 631 ? 111.200 537.473 56.415 1.00 26.91 ? 685 TRP A CH2 1 ATOM 4692 N N . TYR A 1 632 ? 117.464 532.961 52.728 1.00 21.25 ? 686 TYR A N 1 ATOM 4693 C CA . TYR A 1 632 ? 118.715 532.275 53.067 1.00 20.84 ? 686 TYR A CA 1 ATOM 4694 C C . TYR A 1 632 ? 119.933 533.119 52.636 1.00 22.14 ? 686 TYR A C 1 ATOM 4695 O O . TYR A 1 632 ? 120.902 533.208 53.375 1.00 20.67 ? 686 TYR A O 1 ATOM 4696 C CB . TYR A 1 632 ? 118.783 530.891 52.435 1.00 21.36 ? 686 TYR A CB 1 ATOM 4697 C CG . TYR A 1 632 ? 118.253 529.809 53.331 1.00 22.64 ? 686 TYR A CG 1 ATOM 4698 C CD1 . TYR A 1 632 ? 119.049 529.245 54.312 1.00 23.92 ? 686 TYR A CD1 1 ATOM 4699 C CD2 . TYR A 1 632 ? 116.954 529.336 53.193 1.00 23.91 ? 686 TYR A CD2 1 ATOM 4700 C CE1 . TYR A 1 632 ? 118.577 528.224 55.122 1.00 22.49 ? 686 TYR A CE1 1 ATOM 4701 C CE2 . TYR A 1 632 ? 116.467 528.315 54.001 1.00 24.50 ? 686 TYR A CE2 1 ATOM 4702 C CZ . TYR A 1 632 ? 117.283 527.763 54.967 1.00 28.91 ? 686 TYR A CZ 1 ATOM 4703 O OH . TYR A 1 632 ? 116.788 526.787 55.790 1.00 29.52 ? 686 TYR A OH 1 ATOM 4704 N N . GLN A 1 633 ? 119.849 533.766 51.470 1.00 18.97 ? 687 GLN A N 1 ATOM 4705 C CA . GLN A 1 633 ? 120.917 534.599 50.911 1.00 17.56 ? 687 GLN A CA 1 ATOM 4706 C C . GLN A 1 633 ? 121.144 535.829 51.767 1.00 21.72 ? 687 GLN A C 1 ATOM 4707 O O . GLN A 1 633 ? 122.293 536.189 52.012 1.00 23.05 ? 687 GLN A O 1 ATOM 4708 C CB . GLN A 1 633 ? 120.589 534.981 49.474 1.00 18.33 ? 687 GLN A CB 1 ATOM 4709 C CG . GLN A 1 633 ? 120.505 533.755 48.576 1.00 19.18 ? 687 GLN A CG 1 ATOM 4710 C CD . GLN A 1 633 ? 119.934 534.064 47.232 1.00 31.68 ? 687 GLN A CD 1 ATOM 4711 O OE1 . GLN A 1 633 ? 119.160 535.007 47.035 1.00 25.36 ? 687 GLN A OE1 1 ATOM 4712 N NE2 . GLN A 1 633 ? 120.320 533.266 46.274 1.00 23.36 ? 687 GLN A NE2 1 ATOM 4713 N N . MET A 1 634 ? 120.059 536.431 52.275 1.00 16.35 ? 688 MET A N 1 ATOM 4714 C CA . MET A 1 634 ? 120.111 537.614 53.122 1.00 16.73 ? 688 MET A CA 1 ATOM 4715 C C . MET A 1 634 ? 120.705 537.220 54.447 1.00 24.22 ? 688 MET A C 1 ATOM 4716 O O . MET A 1 634 ? 121.626 537.880 54.930 1.00 25.55 ? 688 MET A O 1 ATOM 4717 C CB . MET A 1 634 ? 118.686 538.163 53.317 1.00 18.58 ? 688 MET A CB 1 ATOM 4718 C CG . MET A 1 634 ? 118.571 539.304 54.313 1.00 22.06 ? 688 MET A CG 1 ATOM 4719 S SD . MET A 1 634 ? 119.066 540.921 53.707 1.00 25.92 ? 688 MET A SD 1 ATOM 4720 C CE . MET A 1 634 ? 117.596 541.395 52.764 1.00 21.50 ? 688 MET A CE 1 ATOM 4721 N N . GLY A 1 635 ? 120.178 536.135 55.018 1.00 21.94 ? 689 GLY A N 1 ATOM 4722 C CA . GLY A 1 635 ? 120.590 535.639 56.326 1.00 21.21 ? 689 GLY A CA 1 ATOM 4723 C C . GLY A 1 635 ? 122.031 535.201 56.326 1.00 23.56 ? 689 GLY A C 1 ATOM 4724 O O . GLY A 1 635 ? 122.735 535.383 57.316 1.00 22.29 ? 689 GLY A O 1 ATOM 4725 N N . ALA A 1 636 ? 122.495 534.649 55.186 1.00 21.83 ? 690 ALA A N 1 ATOM 4726 C CA . ALA A 1 636 ? 123.887 534.190 55.034 1.00 20.90 ? 690 ALA A CA 1 ATOM 4727 C C . ALA A 1 636 ? 124.881 535.324 55.161 1.00 26.33 ? 690 ALA A C 1 ATOM 4728 O O . ALA A 1 636 ? 126.039 535.078 55.496 1.00 27.72 ? 690 ALA A O 1 ATOM 4729 C CB . ALA A 1 636 ? 124.070 533.486 53.721 1.00 21.11 ? 690 ALA A CB 1 ATOM 4730 N N . TYR A 1 637 ? 124.422 536.566 54.964 1.00 22.26 ? 691 TYR A N 1 ATOM 4731 C CA . TYR A 1 637 ? 125.260 537.733 55.090 1.00 22.28 ? 691 TYR A CA 1 ATOM 4732 C C . TYR A 1 637 ? 124.892 538.624 56.276 1.00 23.66 ? 691 TYR A C 1 ATOM 4733 O O . TYR A 1 637 ? 125.358 539.755 56.339 1.00 21.89 ? 691 TYR A O 1 ATOM 4734 C CB . TYR A 1 637 ? 125.280 538.485 53.756 1.00 25.08 ? 691 TYR A CB 1 ATOM 4735 C CG . TYR A 1 637 ? 126.231 537.821 52.784 1.00 26.65 ? 691 TYR A CG 1 ATOM 4736 C CD1 . TYR A 1 637 ? 127.583 538.144 52.773 1.00 27.67 ? 691 TYR A CD1 1 ATOM 4737 C CD2 . TYR A 1 637 ? 125.795 536.802 51.936 1.00 27.55 ? 691 TYR A CD2 1 ATOM 4738 C CE1 . TYR A 1 637 ? 128.468 537.510 51.906 1.00 28.03 ? 691 TYR A CE1 1 ATOM 4739 C CE2 . TYR A 1 637 ? 126.679 536.140 51.089 1.00 27.56 ? 691 TYR A CE2 1 ATOM 4740 C CZ . TYR A 1 637 ? 128.013 536.501 51.073 1.00 32.62 ? 691 TYR A CZ 1 ATOM 4741 O OH . TYR A 1 637 ? 128.889 535.845 50.243 1.00 33.39 ? 691 TYR A OH 1 ATOM 4742 N N . GLN A 1 638 ? 124.094 538.092 57.231 1.00 19.90 ? 692 GLN A N 1 ATOM 4743 C CA . GLN A 1 638 ? 123.762 538.766 58.488 1.00 19.64 ? 692 GLN A CA 1 ATOM 4744 C C . GLN A 1 638 ? 124.382 538.030 59.676 1.00 21.01 ? 692 GLN A C 1 ATOM 4745 O O . GLN A 1 638 ? 124.616 536.815 59.584 1.00 18.77 ? 692 GLN A O 1 ATOM 4746 C CB . GLN A 1 638 ? 122.264 538.993 58.657 1.00 21.62 ? 692 GLN A CB 1 ATOM 4747 C CG . GLN A 1 638 ? 121.716 540.003 57.661 1.00 36.27 ? 692 GLN A CG 1 ATOM 4748 C CD . GLN A 1 638 ? 120.226 540.175 57.770 1.00 47.36 ? 692 GLN A CD 1 ATOM 4749 O OE1 . GLN A 1 638 ? 119.538 539.390 58.417 1.00 42.26 ? 692 GLN A OE1 1 ATOM 4750 N NE2 . GLN A 1 638 ? 119.692 541.177 57.084 1.00 29.30 ? 692 GLN A NE2 1 ATOM 4751 N N . PRO A 1 639 ? 124.670 538.745 60.801 1.00 18.34 ? 693 PRO A N 1 ATOM 4752 C CA . PRO A 1 639 ? 125.452 538.126 61.885 1.00 17.73 ? 693 PRO A CA 1 ATOM 4753 C C . PRO A 1 639 ? 124.874 536.860 62.507 1.00 22.53 ? 693 PRO A C 1 ATOM 4754 O O . PRO A 1 639 ? 125.594 535.852 62.562 1.00 21.77 ? 693 PRO A O 1 ATOM 4755 C CB . PRO A 1 639 ? 125.626 539.256 62.878 1.00 19.23 ? 693 PRO A CB 1 ATOM 4756 C CG . PRO A 1 639 ? 125.507 540.513 62.059 1.00 22.45 ? 693 PRO A CG 1 ATOM 4757 C CD . PRO A 1 639 ? 124.488 540.195 61.048 1.00 18.99 ? 693 PRO A CD 1 ATOM 4758 N N . PHE A 1 640 ? 123.594 536.881 62.925 1.00 20.49 ? 694 PHE A N 1 ATOM 4759 C CA . PHE A 1 640 ? 122.958 535.698 63.497 1.00 20.14 ? 694 PHE A CA 1 ATOM 4760 C C . PHE A 1 640 ? 122.099 535.065 62.414 1.00 22.86 ? 694 PHE A C 1 ATOM 4761 O O . PHE A 1 640 ? 121.191 535.708 61.914 1.00 21.76 ? 694 PHE A O 1 ATOM 4762 C CB . PHE A 1 640 ? 122.164 536.049 64.756 1.00 23.02 ? 694 PHE A CB 1 ATOM 4763 C CG . PHE A 1 640 ? 121.447 534.864 65.358 1.00 25.76 ? 694 PHE A CG 1 ATOM 4764 C CD1 . PHE A 1 640 ? 122.160 533.763 65.826 1.00 28.93 ? 694 PHE A CD1 1 ATOM 4765 C CD2 . PHE A 1 640 ? 120.063 534.833 65.431 1.00 27.50 ? 694 PHE A CD2 1 ATOM 4766 C CE1 . PHE A 1 640 ? 121.498 532.649 66.349 1.00 29.01 ? 694 PHE A CE1 1 ATOM 4767 C CE2 . PHE A 1 640 ? 119.401 533.712 65.955 1.00 29.67 ? 694 PHE A CE2 1 ATOM 4768 C CZ . PHE A 1 640 ? 120.119 532.633 66.414 1.00 26.99 ? 694 PHE A CZ 1 ATOM 4769 N N . PHE A 1 641 ? 122.422 533.812 62.020 1.00 19.78 ? 695 PHE A N 1 ATOM 4770 C CA . PHE A 1 641 ? 121.843 533.110 60.876 1.00 18.59 ? 695 PHE A CA 1 ATOM 4771 C C . PHE A 1 641 ? 121.080 531.871 61.259 1.00 21.92 ? 695 PHE A C 1 ATOM 4772 O O . PHE A 1 641 ? 121.654 530.762 61.374 1.00 21.94 ? 695 PHE A O 1 ATOM 4773 C CB . PHE A 1 641 ? 122.996 532.799 59.925 1.00 20.17 ? 695 PHE A CB 1 ATOM 4774 C CG . PHE A 1 641 ? 122.689 532.138 58.613 1.00 20.78 ? 695 PHE A CG 1 ATOM 4775 C CD1 . PHE A 1 641 ? 121.485 532.374 57.958 1.00 24.13 ? 695 PHE A CD1 1 ATOM 4776 C CD2 . PHE A 1 641 ? 123.648 531.375 57.971 1.00 20.11 ? 695 PHE A CD2 1 ATOM 4777 C CE1 . PHE A 1 641 ? 121.234 531.801 56.712 1.00 23.61 ? 695 PHE A CE1 1 ATOM 4778 C CE2 . PHE A 1 641 ? 123.385 530.787 56.740 1.00 20.84 ? 695 PHE A CE2 1 ATOM 4779 C CZ . PHE A 1 641 ? 122.189 531.006 56.117 1.00 18.73 ? 695 PHE A CZ 1 ATOM 4780 N N . ARG A 1 642 ? 119.765 532.067 61.465 1.00 17.76 ? 696 ARG A N 1 ATOM 4781 C CA . ARG A 1 642 ? 118.841 531.046 61.905 1.00 17.23 ? 696 ARG A CA 1 ATOM 4782 C C . ARG A 1 642 ? 117.553 531.032 61.122 1.00 25.26 ? 696 ARG A C 1 ATOM 4783 O O . ARG A 1 642 ? 116.862 532.049 61.013 1.00 25.55 ? 696 ARG A O 1 ATOM 4784 C CB . ARG A 1 642 ? 118.509 531.235 63.405 1.00 16.14 ? 696 ARG A CB 1 ATOM 4785 C CG . ARG A 1 642 ? 117.503 530.187 63.959 1.00 14.57 ? 696 ARG A CG 1 ATOM 4786 C CD . ARG A 1 642 ? 117.137 530.397 65.392 1.00 17.06 ? 696 ARG A CD 1 ATOM 4787 N NE . ARG A 1 642 ? 116.189 531.504 65.528 1.00 30.13 ? 696 ARG A NE 1 ATOM 4788 C CZ . ARG A 1 642 ? 115.266 531.586 66.477 1.00 34.10 ? 696 ARG A CZ 1 ATOM 4789 N NH1 . ARG A 1 642 ? 115.149 530.627 67.381 1.00 22.62 ? 696 ARG A NH1 1 ATOM 4790 N NH2 . ARG A 1 642 ? 114.436 532.611 66.512 1.00 27.77 ? 696 ARG A NH2 1 ATOM 4791 N N . ALA A 1 643 ? 117.186 529.840 60.651 1.00 24.40 ? 697 ALA A N 1 ATOM 4792 C CA . ALA A 1 643 ? 115.885 529.586 60.037 1.00 24.11 ? 697 ALA A CA 1 ATOM 4793 C C . ALA A 1 643 ? 115.018 529.136 61.170 1.00 27.80 ? 697 ALA A C 1 ATOM 4794 O O . ALA A 1 643 ? 115.436 528.313 61.972 1.00 29.20 ? 697 ALA A O 1 ATOM 4795 C CB . ALA A 1 643 ? 115.966 528.496 58.988 1.00 24.46 ? 697 ALA A CB 1 ATOM 4796 N N . HIS A 1 644 ? 113.820 529.698 61.258 1.00 22.28 ? 698 HIS A N 1 ATOM 4797 C CA . HIS A 1 644 ? 112.872 529.413 62.322 1.00 19.90 ? 698 HIS A CA 1 ATOM 4798 C C . HIS A 1 644 ? 111.475 529.654 61.778 1.00 23.51 ? 698 HIS A C 1 ATOM 4799 O O . HIS A 1 644 ? 111.310 530.397 60.807 1.00 23.43 ? 698 HIS A O 1 ATOM 4800 C CB . HIS A 1 644 ? 113.183 530.275 63.554 1.00 18.79 ? 698 HIS A CB 1 ATOM 4801 C CG . HIS A 1 644 ? 112.351 529.936 64.745 1.00 20.30 ? 698 HIS A CG 1 ATOM 4802 N ND1 . HIS A 1 644 ? 112.291 528.658 65.235 1.00 21.31 ? 698 HIS A ND1 1 ATOM 4803 C CD2 . HIS A 1 644 ? 111.591 530.734 65.523 1.00 20.12 ? 698 HIS A CD2 1 ATOM 4804 C CE1 . HIS A 1 644 ? 111.485 528.708 66.280 1.00 20.06 ? 698 HIS A CE1 1 ATOM 4805 N NE2 . HIS A 1 644 ? 111.022 529.932 66.467 1.00 20.22 ? 698 HIS A NE2 1 ATOM 4806 N N . ALA A 1 645 ? 110.477 529.002 62.385 1.00 20.08 ? 699 ALA A N 1 ATOM 4807 C CA . ALA A 1 645 ? 109.106 529.010 61.890 1.00 20.46 ? 699 ALA A CA 1 ATOM 4808 C C . ALA A 1 645 ? 108.115 528.715 63.015 1.00 25.73 ? 699 ALA A C 1 ATOM 4809 O O . ALA A 1 645 ? 108.400 527.919 63.910 1.00 22.93 ? 699 ALA A O 1 ATOM 4810 C CB . ALA A 1 645 ? 108.964 527.960 60.787 1.00 20.62 ? 699 ALA A CB 1 ATOM 4811 N N . HIS A 1 646 ? 106.945 529.374 62.955 1.00 24.77 ? 700 HIS A N 1 ATOM 4812 C CA . HIS A 1 646 ? 105.820 529.214 63.881 1.00 24.69 ? 700 HIS A CA 1 ATOM 4813 C C . HIS A 1 646 ? 105.204 527.770 63.828 1.00 29.11 ? 700 HIS A C 1 ATOM 4814 O O . HIS A 1 646 ? 105.387 527.039 62.848 1.00 28.38 ? 700 HIS A O 1 ATOM 4815 C CB . HIS A 1 646 ? 104.808 530.313 63.551 1.00 25.72 ? 700 HIS A CB 1 ATOM 4816 C CG . HIS A 1 646 ? 103.571 530.300 64.365 1.00 30.20 ? 700 HIS A CG 1 ATOM 4817 N ND1 . HIS A 1 646 ? 102.408 529.681 63.906 1.00 32.52 ? 700 HIS A ND1 1 ATOM 4818 C CD2 . HIS A 1 646 ? 103.342 530.825 65.589 1.00 32.37 ? 700 HIS A CD2 1 ATOM 4819 C CE1 . HIS A 1 646 ? 101.530 529.830 64.877 1.00 32.20 ? 700 HIS A CE1 1 ATOM 4820 N NE2 . HIS A 1 646 ? 102.049 530.513 65.911 1.00 32.49 ? 700 HIS A NE2 1 ATOM 4821 N N . LEU A 1 647 ? 104.508 527.365 64.910 1.00 27.74 ? 701 LEU A N 1 ATOM 4822 C CA . LEU A 1 647 ? 103.911 526.036 65.110 1.00 27.68 ? 701 LEU A CA 1 ATOM 4823 C C . LEU A 1 647 ? 103.043 525.559 63.950 1.00 36.10 ? 701 LEU A C 1 ATOM 4824 O O . LEU A 1 647 ? 103.083 524.386 63.595 1.00 36.33 ? 701 LEU A O 1 ATOM 4825 C CB . LEU A 1 647 ? 103.108 526.037 66.431 1.00 26.70 ? 701 LEU A CB 1 ATOM 4826 C CG . LEU A 1 647 ? 102.561 524.715 66.986 1.00 30.03 ? 701 LEU A CG 1 ATOM 4827 C CD1 . LEU A 1 647 ? 103.645 523.661 67.198 1.00 28.64 ? 701 LEU A CD1 1 ATOM 4828 C CD2 . LEU A 1 647 ? 101.778 524.939 68.268 1.00 31.24 ? 701 LEU A CD2 1 ATOM 4829 N N . ASP A 1 648 ? 102.304 526.474 63.333 1.00 34.81 ? 702 ASP A N 1 ATOM 4830 C CA . ASP A 1 648 ? 101.329 526.115 62.309 1.00 35.44 ? 702 ASP A CA 1 ATOM 4831 C C . ASP A 1 648 ? 101.840 526.168 60.869 1.00 39.74 ? 702 ASP A C 1 ATOM 4832 O O . ASP A 1 648 ? 101.065 525.944 59.930 1.00 39.37 ? 702 ASP A O 1 ATOM 4833 C CB . ASP A 1 648 ? 100.066 526.983 62.488 1.00 38.14 ? 702 ASP A CB 1 ATOM 4834 C CG . ASP A 1 648 ? 99.402 526.881 63.869 1.00 53.10 ? 702 ASP A CG 1 ATOM 4835 O OD1 . ASP A 1 648 ? 99.482 525.784 64.504 1.00 53.88 ? 702 ASP A OD1 1 ATOM 4836 O OD2 . ASP A 1 648 ? 98.764 527.875 64.296 1.00 61.17 ? 702 ASP A OD2 1 ATOM 4837 N N . THR A 1 649 ? 103.140 526.410 60.687 1.00 36.05 ? 703 THR A N 1 ATOM 4838 C CA . THR A 1 649 ? 103.725 526.483 59.351 1.00 34.69 ? 703 THR A CA 1 ATOM 4839 C C . THR A 1 649 ? 104.081 525.095 58.856 1.00 33.32 ? 703 THR A C 1 ATOM 4840 O O . THR A 1 649 ? 104.349 524.203 59.659 1.00 31.07 ? 703 THR A O 1 ATOM 4841 C CB . THR A 1 649 ? 105.004 527.348 59.373 1.00 41.36 ? 703 THR A CB 1 ATOM 4842 O OG1 . THR A 1 649 ? 105.971 526.716 60.223 1.00 41.87 ? 703 THR A OG1 1 ATOM 4843 C CG2 . THR A 1 649 ? 104.737 528.755 59.832 1.00 37.36 ? 703 THR A CG2 1 ATOM 4844 N N . GLY A 1 650 ? 104.157 524.958 57.534 1.00 28.71 ? 704 GLY A N 1 ATOM 4845 C CA . GLY A 1 650 ? 104.658 523.757 56.878 1.00 27.76 ? 704 GLY A CA 1 ATOM 4846 C C . GLY A 1 650 ? 106.152 523.609 57.127 1.00 31.71 ? 704 GLY A C 1 ATOM 4847 O O . GLY A 1 650 ? 106.858 524.596 57.409 1.00 31.06 ? 704 GLY A O 1 ATOM 4848 N N . ARG A 1 651 ? 106.640 522.370 57.072 1.00 28.42 ? 705 ARG A N 1 ATOM 4849 C CA . ARG A 1 651 ? 108.056 522.078 57.260 1.00 28.24 ? 705 ARG A CA 1 ATOM 4850 C C . ARG A 1 651 ? 108.870 522.739 56.168 1.00 31.70 ? 705 ARG A C 1 ATOM 4851 O O . ARG A 1 651 ? 108.484 522.684 54.997 1.00 30.05 ? 705 ARG A O 1 ATOM 4852 C CB . ARG A 1 651 ? 108.292 520.562 57.285 1.00 29.31 ? 705 ARG A CB 1 ATOM 4853 C CG . ARG A 1 651 ? 107.687 519.907 58.519 1.00 24.73 ? 705 ARG A CG 1 ATOM 4854 C CD . ARG A 1 651 ? 108.479 520.235 59.774 1.00 21.71 ? 705 ARG A CD 1 ATOM 4855 N NE . ARG A 1 651 ? 109.749 519.525 59.780 1.00 22.54 ? 705 ARG A NE 1 ATOM 4856 C CZ . ARG A 1 651 ? 110.161 518.713 60.741 1.00 45.44 ? 705 ARG A CZ 1 ATOM 4857 N NH1 . ARG A 1 651 ? 109.432 518.546 61.841 1.00 39.51 ? 705 ARG A NH1 1 ATOM 4858 N NH2 . ARG A 1 651 ? 111.311 518.068 60.618 1.00 34.89 ? 705 ARG A NH2 1 ATOM 4859 N N . ARG A 1 652 ? 109.951 523.426 56.548 1.00 28.75 ? 706 ARG A N 1 ATOM 4860 C CA . ARG A 1 652 ? 110.745 524.119 55.536 1.00 28.08 ? 706 ARG A CA 1 ATOM 4861 C C . ARG A 1 652 ? 112.261 523.882 55.625 1.00 31.43 ? 706 ARG A C 1 ATOM 4862 O O . ARG A 1 652 ? 113.042 524.739 55.222 1.00 30.23 ? 706 ARG A O 1 ATOM 4863 C CB . ARG A 1 652 ? 110.428 525.611 55.430 1.00 24.38 ? 706 ARG A CB 1 ATOM 4864 C CG . ARG A 1 652 ? 110.014 526.353 56.674 1.00 28.39 ? 706 ARG A CG 1 ATOM 4865 C CD . ARG A 1 652 ? 109.761 527.772 56.214 1.00 25.43 ? 706 ARG A CD 1 ATOM 4866 N NE . ARG A 1 652 ? 108.672 528.475 56.910 1.00 38.51 ? 706 ARG A NE 1 ATOM 4867 C CZ . ARG A 1 652 ? 108.826 529.538 57.697 1.00 38.85 ? 706 ARG A CZ 1 ATOM 4868 N NH1 . ARG A 1 652 ? 110.036 529.996 57.974 1.00 16.36 ? 706 ARG A NH1 1 ATOM 4869 N NH2 . ARG A 1 652 ? 107.771 530.133 58.232 1.00 27.86 ? 706 ARG A NH2 1 ATOM 4870 N N . GLU A 1 653 ? 112.665 522.671 56.014 1.00 27.98 ? 707 GLU A N 1 ATOM 4871 C CA . GLU A 1 653 ? 114.070 522.308 55.967 1.00 28.15 ? 707 GLU A CA 1 ATOM 4872 C C . GLU A 1 653 ? 114.445 522.427 54.488 1.00 35.36 ? 707 GLU A C 1 ATOM 4873 O O . GLU A 1 653 ? 113.614 522.155 53.592 1.00 36.41 ? 707 GLU A O 1 ATOM 4874 C CB . GLU A 1 653 ? 114.309 520.907 56.500 1.00 29.76 ? 707 GLU A CB 1 ATOM 4875 C CG . GLU A 1 653 ? 114.152 520.791 58.017 1.00 35.10 ? 707 GLU A CG 1 ATOM 4876 C CD . GLU A 1 653 ? 112.747 521.069 58.519 1.00 43.27 ? 707 GLU A CD 1 ATOM 4877 O OE1 . GLU A 1 653 ? 111.794 520.490 57.947 1.00 16.18 ? 707 GLU A OE1 1 ATOM 4878 O OE2 . GLU A 1 653 ? 112.595 521.924 59.421 1.00 36.40 ? 707 GLU A OE2 1 ATOM 4879 N N . PRO A 1 654 ? 115.655 522.921 54.204 1.00 30.70 ? 708 PRO A N 1 ATOM 4880 C CA . PRO A 1 654 ? 115.938 523.360 52.832 1.00 30.31 ? 708 PRO A CA 1 ATOM 4881 C C . PRO A 1 654 ? 115.944 522.287 51.755 1.00 32.15 ? 708 PRO A C 1 ATOM 4882 O O . PRO A 1 654 ? 115.672 522.610 50.597 1.00 30.92 ? 708 PRO A O 1 ATOM 4883 C CB . PRO A 1 654 ? 117.269 524.097 52.948 1.00 32.63 ? 708 PRO A CB 1 ATOM 4884 C CG . PRO A 1 654 ? 117.851 523.658 54.249 1.00 36.38 ? 708 PRO A CG 1 ATOM 4885 C CD . PRO A 1 654 ? 116.716 523.338 55.145 1.00 31.29 ? 708 PRO A CD 1 ATOM 4886 N N . TRP A 1 655 ? 116.161 521.033 52.120 1.00 29.02 ? 709 TRP A N 1 ATOM 4887 C CA . TRP A 1 655 ? 116.071 519.953 51.142 1.00 28.65 ? 709 TRP A CA 1 ATOM 4888 C C . TRP A 1 655 ? 114.635 519.525 50.780 1.00 35.11 ? 709 TRP A C 1 ATOM 4889 O O . TRP A 1 655 ? 114.487 518.614 49.973 1.00 35.13 ? 709 TRP A O 1 ATOM 4890 C CB . TRP A 1 655 ? 116.862 518.734 51.590 1.00 26.79 ? 709 TRP A CB 1 ATOM 4891 C CG . TRP A 1 655 ? 116.374 518.162 52.875 1.00 27.64 ? 709 TRP A CG 1 ATOM 4892 C CD1 . TRP A 1 655 ? 115.401 517.221 53.044 1.00 30.53 ? 709 TRP A CD1 1 ATOM 4893 C CD2 . TRP A 1 655 ? 116.804 518.537 54.179 1.00 27.13 ? 709 TRP A CD2 1 ATOM 4894 N NE1 . TRP A 1 655 ? 115.214 516.971 54.375 1.00 30.22 ? 709 TRP A NE1 1 ATOM 4895 C CE2 . TRP A 1 655 ? 116.062 517.763 55.103 1.00 31.20 ? 709 TRP A CE2 1 ATOM 4896 C CE3 . TRP A 1 655 ? 117.781 519.417 54.659 1.00 27.45 ? 709 TRP A CE3 1 ATOM 4897 C CZ2 . TRP A 1 655 ? 116.265 517.842 56.487 1.00 29.65 ? 709 TRP A CZ2 1 ATOM 4898 C CZ3 . TRP A 1 655 ? 117.982 519.501 56.029 1.00 29.09 ? 709 TRP A CZ3 1 ATOM 4899 C CH2 . TRP A 1 655 ? 117.227 518.721 56.929 1.00 29.81 ? 709 TRP A CH2 1 ATOM 4900 N N . LEU A 1 656 ? 113.588 520.136 51.369 1.00 32.70 ? 710 LEU A N 1 ATOM 4901 C CA . LEU A 1 656 ? 112.211 519.773 51.023 1.00 31.11 ? 710 LEU A CA 1 ATOM 4902 C C . LEU A 1 656 ? 111.757 520.479 49.771 1.00 34.94 ? 710 LEU A C 1 ATOM 4903 O O . LEU A 1 656 ? 110.697 520.175 49.223 1.00 36.02 ? 710 LEU A O 1 ATOM 4904 C CB . LEU A 1 656 ? 111.259 520.075 52.186 1.00 30.00 ? 710 LEU A CB 1 ATOM 4905 C CG . LEU A 1 656 ? 111.581 519.337 53.463 1.00 32.37 ? 710 LEU A CG 1 ATOM 4906 C CD1 . LEU A 1 656 ? 110.653 519.753 54.561 1.00 32.29 ? 710 LEU A CD1 1 ATOM 4907 C CD2 . LEU A 1 656 ? 111.543 517.838 53.272 1.00 31.47 ? 710 LEU A CD2 1 ATOM 4908 N N . LEU A 1 657 ? 112.554 521.416 49.310 1.00 30.79 ? 711 LEU A N 1 ATOM 4909 C CA . LEU A 1 657 ? 112.241 522.180 48.118 1.00 30.43 ? 711 LEU A CA 1 ATOM 4910 C C . LEU A 1 657 ? 112.729 521.528 46.826 1.00 31.81 ? 711 LEU A C 1 ATOM 4911 O O . LEU A 1 657 ? 113.590 520.648 46.829 1.00 29.34 ? 711 LEU A O 1 ATOM 4912 C CB . LEU A 1 657 ? 112.836 523.595 48.231 1.00 30.68 ? 711 LEU A CB 1 ATOM 4913 C CG . LEU A 1 657 ? 112.498 524.449 49.428 1.00 35.21 ? 711 LEU A CG 1 ATOM 4914 C CD1 . LEU A 1 657 ? 112.963 525.854 49.191 1.00 34.33 ? 711 LEU A CD1 1 ATOM 4915 C CD2 . LEU A 1 657 ? 111.024 524.523 49.623 1.00 42.79 ? 711 LEU A CD2 1 ATOM 4916 N N . ALA A 1 658 ? 112.199 522.015 45.703 1.00 30.40 ? 712 ALA A N 1 ATOM 4917 C CA . ALA A 1 658 ? 112.617 521.549 44.382 1.00 31.05 ? 712 ALA A CA 1 ATOM 4918 C C . ALA A 1 658 ? 114.106 521.877 44.211 1.00 37.35 ? 712 ALA A C 1 ATOM 4919 O O . ALA A 1 658 ? 114.599 522.878 44.758 1.00 37.19 ? 712 ALA A O 1 ATOM 4920 C CB . ALA A 1 658 ? 111.778 522.201 43.285 1.00 31.28 ? 712 ALA A CB 1 ATOM 4921 N N . SER A 1 659 ? 114.803 521.046 43.433 1.00 34.83 ? 713 SER A N 1 ATOM 4922 C CA . SER A 1 659 ? 116.245 521.093 43.282 1.00 35.33 ? 713 SER A CA 1 ATOM 4923 C C . SER A 1 659 ? 116.851 522.482 42.963 1.00 40.72 ? 713 SER A C 1 ATOM 4924 O O . SER A 1 659 ? 117.908 522.777 43.522 1.00 40.30 ? 713 SER A O 1 ATOM 4925 C CB . SER A 1 659 ? 116.724 520.046 42.288 1.00 39.64 ? 713 SER A CB 1 ATOM 4926 O OG . SER A 1 659 ? 116.552 520.496 40.957 1.00 53.42 ? 713 SER A OG 1 ATOM 4927 N N . GLN A 1 660 ? 116.205 523.344 42.136 1.00 37.92 ? 714 GLN A N 1 ATOM 4928 C CA . GLN A 1 660 ? 116.782 524.674 41.837 1.00 36.65 ? 714 GLN A CA 1 ATOM 4929 C C . GLN A 1 660 ? 116.863 525.535 43.104 1.00 37.18 ? 714 GLN A C 1 ATOM 4930 O O . GLN A 1 660 ? 117.791 526.333 43.262 1.00 36.81 ? 714 GLN A O 1 ATOM 4931 C CB . GLN A 1 660 ? 116.022 525.416 40.723 1.00 38.02 ? 714 GLN A CB 1 ATOM 4932 C CG . GLN A 1 660 ? 114.641 525.903 41.153 1.00 61.34 ? 714 GLN A CG 1 ATOM 4933 C CD . GLN A 1 660 ? 113.770 526.440 40.048 1.00 81.29 ? 714 GLN A CD 1 ATOM 4934 O OE1 . GLN A 1 660 ? 114.086 527.462 39.417 1.00 80.71 ? 714 GLN A OE1 1 ATOM 4935 N NE2 . GLN A 1 660 ? 112.597 525.826 39.874 1.00 60.51 ? 714 GLN A NE2 1 ATOM 4936 N N . TYR A 1 661 ? 115.870 525.384 43.983 1.00 30.50 ? 715 TYR A N 1 ATOM 4937 C CA . TYR A 1 661 ? 115.805 526.134 45.226 1.00 28.61 ? 715 TYR A CA 1 ATOM 4938 C C . TYR A 1 661 ? 116.803 525.554 46.223 1.00 28.85 ? 715 TYR A C 1 ATOM 4939 O O . TYR A 1 661 ? 117.524 526.305 46.889 1.00 28.32 ? 715 TYR A O 1 ATOM 4940 C CB . TYR A 1 661 ? 114.375 526.134 45.785 1.00 29.89 ? 715 TYR A CB 1 ATOM 4941 C CG . TYR A 1 661 ? 113.327 526.673 44.831 1.00 31.05 ? 715 TYR A CG 1 ATOM 4942 C CD1 . TYR A 1 661 ? 113.294 528.022 44.489 1.00 32.74 ? 715 TYR A CD1 1 ATOM 4943 C CD2 . TYR A 1 661 ? 112.351 525.836 44.290 1.00 32.27 ? 715 TYR A CD2 1 ATOM 4944 C CE1 . TYR A 1 661 ? 112.332 528.526 43.608 1.00 32.52 ? 715 TYR A CE1 1 ATOM 4945 C CE2 . TYR A 1 661 ? 111.381 526.322 43.411 1.00 33.64 ? 715 TYR A CE2 1 ATOM 4946 C CZ . TYR A 1 661 ? 111.380 527.671 43.068 1.00 44.33 ? 715 TYR A CZ 1 ATOM 4947 O OH . TYR A 1 661 ? 110.438 528.174 42.200 1.00 44.77 ? 715 TYR A OH 1 ATOM 4948 N N . GLN A 1 662 ? 116.880 524.220 46.310 1.00 22.59 ? 716 GLN A N 1 ATOM 4949 C CA . GLN A 1 662 ? 117.875 523.585 47.180 1.00 22.28 ? 716 GLN A CA 1 ATOM 4950 C C . GLN A 1 662 ? 119.307 524.045 46.794 1.00 27.88 ? 716 GLN A C 1 ATOM 4951 O O . GLN A 1 662 ? 120.150 524.279 47.660 1.00 26.39 ? 716 GLN A O 1 ATOM 4952 C CB . GLN A 1 662 ? 117.869 522.063 47.017 1.00 23.16 ? 716 GLN A CB 1 ATOM 4953 C CG . GLN A 1 662 ? 116.620 521.308 47.380 1.00 25.50 ? 716 GLN A CG 1 ATOM 4954 C CD . GLN A 1 662 ? 116.887 519.813 47.322 1.00 47.50 ? 716 GLN A CD 1 ATOM 4955 O OE1 . GLN A 1 662 ? 118.008 519.343 47.523 1.00 46.00 ? 716 GLN A OE1 1 ATOM 4956 N NE2 . GLN A 1 662 ? 115.858 519.024 47.090 1.00 43.50 ? 716 GLN A NE2 1 ATOM 4957 N N . ASP A 1 663 ? 119.583 524.125 45.482 1.00 26.32 ? 717 ASP A N 1 ATOM 4958 C CA . ASP A 1 663 ? 120.907 524.477 44.975 1.00 25.33 ? 717 ASP A CA 1 ATOM 4959 C C . ASP A 1 663 ? 121.301 525.876 45.330 1.00 24.20 ? 717 ASP A C 1 ATOM 4960 O O . ASP A 1 663 ? 122.447 526.112 45.690 1.00 24.30 ? 717 ASP A O 1 ATOM 4961 C CB . ASP A 1 663 ? 120.992 524.225 43.453 1.00 27.65 ? 717 ASP A CB 1 ATOM 4962 C CG . ASP A 1 663 ? 120.998 522.749 43.035 1.00 37.25 ? 717 ASP A CG 1 ATOM 4963 O OD1 . ASP A 1 663 ? 121.075 521.845 43.949 1.00 37.05 ? 717 ASP A OD1 1 ATOM 4964 O OD2 . ASP A 1 663 ? 120.934 522.487 41.818 1.00 37.82 ? 717 ASP A OD2 1 ATOM 4965 N N . ALA A 1 664 ? 120.363 526.797 45.241 1.00 18.42 ? 718 ALA A N 1 ATOM 4966 C CA . ALA A 1 664 ? 120.628 528.190 45.555 1.00 17.87 ? 718 ALA A CA 1 ATOM 4967 C C . ALA A 1 664 ? 120.873 528.327 47.048 1.00 27.53 ? 718 ALA A C 1 ATOM 4968 O O . ALA A 1 664 ? 121.735 529.105 47.464 1.00 30.26 ? 718 ALA A O 1 ATOM 4969 C CB . ALA A 1 664 ? 119.455 529.046 45.135 1.00 17.51 ? 718 ALA A CB 1 ATOM 4970 N N . ILE A 1 665 ? 120.140 527.555 47.854 1.00 24.36 ? 719 ILE A N 1 ATOM 4971 C CA . ILE A 1 665 ? 120.296 527.602 49.304 1.00 23.32 ? 719 ILE A CA 1 ATOM 4972 C C . ILE A 1 665 ? 121.627 527.039 49.703 1.00 25.41 ? 719 ILE A C 1 ATOM 4973 O O . ILE A 1 665 ? 122.331 527.643 50.513 1.00 24.97 ? 719 ILE A O 1 ATOM 4974 C CB . ILE A 1 665 ? 119.136 526.917 50.031 1.00 25.77 ? 719 ILE A CB 1 ATOM 4975 C CG1 . ILE A 1 665 ? 117.856 527.754 49.849 1.00 25.78 ? 719 ILE A CG1 1 ATOM 4976 C CG2 . ILE A 1 665 ? 119.485 526.737 51.525 1.00 24.96 ? 719 ILE A CG2 1 ATOM 4977 C CD1 . ILE A 1 665 ? 116.587 527.056 50.254 1.00 31.11 ? 719 ILE A CD1 1 ATOM 4978 N N . ARG A 1 666 ? 122.004 525.915 49.091 1.00 22.04 ? 720 ARG A N 1 ATOM 4979 C CA . ARG A 1 666 ? 123.304 525.269 49.350 1.00 21.94 ? 720 ARG A CA 1 ATOM 4980 C C . ARG A 1 666 ? 124.434 526.242 49.023 1.00 25.84 ? 720 ARG A C 1 ATOM 4981 O O . ARG A 1 666 ? 125.364 526.374 49.809 1.00 24.71 ? 720 ARG A O 1 ATOM 4982 C CB . ARG A 1 666 ? 123.451 523.965 48.547 1.00 20.23 ? 720 ARG A CB 1 ATOM 4983 C CG . ARG A 1 666 ? 124.710 523.170 48.888 1.00 24.94 ? 720 ARG A CG 1 ATOM 4984 C CD . ARG A 1 666 ? 124.922 521.948 47.999 1.00 21.23 ? 720 ARG A CD 1 ATOM 4985 N NE . ARG A 1 666 ? 123.851 520.978 48.168 1.00 15.10 ? 720 ARG A NE 1 ATOM 4986 C CZ . ARG A 1 666 ? 122.797 520.840 47.368 1.00 30.15 ? 720 ARG A CZ 1 ATOM 4987 N NH1 . ARG A 1 666 ? 122.693 521.564 46.265 1.00 31.77 ? 720 ARG A NH1 1 ATOM 4988 N NH2 . ARG A 1 666 ? 121.853 519.955 47.654 1.00 26.22 ? 720 ARG A NH2 1 ATOM 4989 N N . ASP A 1 667 ? 124.315 526.960 47.905 1.00 25.41 ? 721 ASP A N 1 ATOM 4990 C CA . ASP A 1 667 ? 125.285 527.973 47.501 1.00 26.39 ? 721 ASP A CA 1 ATOM 4991 C C . ASP A 1 667 ? 125.416 529.066 48.575 1.00 24.46 ? 721 ASP A C 1 ATOM 4992 O O . ASP A 1 667 ? 126.527 529.446 48.931 1.00 20.60 ? 721 ASP A O 1 ATOM 4993 C CB . ASP A 1 667 ? 124.899 528.553 46.124 1.00 29.77 ? 721 ASP A CB 1 ATOM 4994 C CG . ASP A 1 667 ? 125.818 529.651 45.583 1.00 46.84 ? 721 ASP A CG 1 ATOM 4995 O OD1 . ASP A 1 667 ? 127.063 529.580 45.821 1.00 45.87 ? 721 ASP A OD1 1 ATOM 4996 O OD2 . ASP A 1 667 ? 125.313 530.535 44.862 1.00 59.89 ? 721 ASP A OD2 1 ATOM 4997 N N . ALA A 1 668 ? 124.282 529.541 49.104 1.00 21.65 ? 722 ALA A N 1 ATOM 4998 C CA . ALA A 1 668 ? 124.295 530.556 50.142 1.00 21.40 ? 722 ALA A CA 1 ATOM 4999 C C . ALA A 1 668 ? 125.032 530.058 51.371 1.00 25.44 ? 722 ALA A C 1 ATOM 5000 O O . ALA A 1 668 ? 125.891 530.771 51.900 1.00 25.99 ? 722 ALA A O 1 ATOM 5001 C CB . ALA A 1 668 ? 122.869 530.968 50.500 1.00 22.15 ? 722 ALA A CB 1 ATOM 5002 N N . LEU A 1 669 ? 124.704 528.830 51.814 1.00 21.70 ? 723 LEU A N 1 ATOM 5003 C CA . LEU A 1 669 ? 125.307 528.221 52.993 1.00 20.57 ? 723 LEU A CA 1 ATOM 5004 C C . LEU A 1 669 ? 126.830 528.042 52.816 1.00 20.83 ? 723 LEU A C 1 ATOM 5005 O O . LEU A 1 669 ? 127.591 528.281 53.741 1.00 17.95 ? 723 LEU A O 1 ATOM 5006 C CB . LEU A 1 669 ? 124.639 526.873 53.299 1.00 20.70 ? 723 LEU A CB 1 ATOM 5007 C CG . LEU A 1 669 ? 123.174 526.877 53.691 1.00 25.12 ? 723 LEU A CG 1 ATOM 5008 C CD1 . LEU A 1 669 ? 122.687 525.438 53.794 1.00 25.69 ? 723 LEU A CD1 1 ATOM 5009 C CD2 . LEU A 1 669 ? 122.961 527.573 55.048 1.00 25.94 ? 723 LEU A CD2 1 ATOM 5010 N N . PHE A 1 670 ? 127.264 527.599 51.636 1.00 18.16 ? 724 PHE A N 1 ATOM 5011 C CA . PHE A 1 670 ? 128.683 527.436 51.324 1.00 18.80 ? 724 PHE A CA 1 ATOM 5012 C C . PHE A 1 670 ? 129.417 528.789 51.439 1.00 26.59 ? 724 PHE A C 1 ATOM 5013 O O . PHE A 1 670 ? 130.479 528.861 52.089 1.00 25.32 ? 724 PHE A O 1 ATOM 5014 C CB . PHE A 1 670 ? 128.870 526.762 49.935 1.00 20.36 ? 724 PHE A CB 1 ATOM 5015 C CG . PHE A 1 670 ? 128.863 525.237 49.952 1.00 21.85 ? 724 PHE A CG 1 ATOM 5016 C CD1 . PHE A 1 670 ? 127.797 524.529 50.503 1.00 23.36 ? 724 PHE A CD1 1 ATOM 5017 C CD2 . PHE A 1 670 ? 129.940 524.513 49.442 1.00 23.82 ? 724 PHE A CD2 1 ATOM 5018 C CE1 . PHE A 1 670 ? 127.803 523.129 50.531 1.00 23.59 ? 724 PHE A CE1 1 ATOM 5019 C CE2 . PHE A 1 670 ? 129.948 523.110 49.478 1.00 25.54 ? 724 PHE A CE2 1 ATOM 5020 C CZ . PHE A 1 670 ? 128.878 522.426 50.019 1.00 22.79 ? 724 PHE A CZ 1 ATOM 5021 N N . GLN A 1 671 ? 128.796 529.875 50.893 1.00 23.82 ? 725 GLN A N 1 ATOM 5022 C CA . GLN A 1 671 ? 129.358 531.226 50.978 1.00 23.18 ? 725 GLN A CA 1 ATOM 5023 C C . GLN A 1 671 ? 129.562 531.659 52.422 1.00 26.93 ? 725 GLN A C 1 ATOM 5024 O O . GLN A 1 671 ? 130.635 532.164 52.778 1.00 26.21 ? 725 GLN A O 1 ATOM 5025 C CB . GLN A 1 671 ? 128.515 532.233 50.237 1.00 23.94 ? 725 GLN A CB 1 ATOM 5026 C CG . GLN A 1 671 ? 128.642 532.106 48.730 1.00 19.63 ? 725 GLN A CG 1 ATOM 5027 C CD . GLN A 1 671 ? 127.814 533.138 48.014 1.00 34.39 ? 725 GLN A CD 1 ATOM 5028 O OE1 . GLN A 1 671 ? 127.788 534.314 48.361 1.00 32.94 ? 725 GLN A OE1 1 ATOM 5029 N NE2 . GLN A 1 671 ? 127.184 532.737 46.941 1.00 33.75 ? 725 GLN A NE2 1 ATOM 5030 N N . ARG A 1 672 ? 128.556 531.416 53.265 1.00 22.91 ? 726 ARG A N 1 ATOM 5031 C CA . ARG A 1 672 ? 128.641 531.752 54.684 1.00 20.99 ? 726 ARG A CA 1 ATOM 5032 C C . ARG A 1 672 ? 129.749 530.957 55.381 1.00 23.88 ? 726 ARG A C 1 ATOM 5033 O O . ARG A 1 672 ? 130.617 531.557 56.013 1.00 22.27 ? 726 ARG A O 1 ATOM 5034 C CB . ARG A 1 672 ? 127.282 531.559 55.356 1.00 16.27 ? 726 ARG A CB 1 ATOM 5035 C CG . ARG A 1 672 ? 127.287 531.665 56.876 1.00 24.09 ? 726 ARG A CG 1 ATOM 5036 C CD . ARG A 1 672 ? 127.914 532.951 57.372 1.00 21.29 ? 726 ARG A CD 1 ATOM 5037 N NE . ARG A 1 672 ? 127.615 533.172 58.785 1.00 23.25 ? 726 ARG A NE 1 ATOM 5038 C CZ . ARG A 1 672 ? 126.718 534.045 59.239 1.00 35.42 ? 726 ARG A CZ 1 ATOM 5039 N NH1 . ARG A 1 672 ? 126.037 534.814 58.392 1.00 18.16 ? 726 ARG A NH1 1 ATOM 5040 N NH2 . ARG A 1 672 ? 126.505 534.168 60.543 1.00 20.92 ? 726 ARG A NH2 1 ATOM 5041 N N . TYR A 1 673 ? 129.757 529.622 55.208 1.00 19.92 ? 727 TYR A N 1 ATOM 5042 C CA . TYR A 1 673 ? 130.744 528.767 55.838 1.00 17.51 ? 727 TYR A CA 1 ATOM 5043 C C . TYR A 1 673 ? 132.165 529.134 55.394 1.00 24.54 ? 727 TYR A C 1 ATOM 5044 O O . TYR A 1 673 ? 133.080 529.199 56.232 1.00 24.26 ? 727 TYR A O 1 ATOM 5045 C CB . TYR A 1 673 ? 130.398 527.275 55.668 1.00 17.45 ? 727 TYR A CB 1 ATOM 5046 C CG . TYR A 1 673 ? 129.446 526.812 56.757 1.00 18.43 ? 727 TYR A CG 1 ATOM 5047 C CD1 . TYR A 1 673 ? 128.098 527.148 56.719 1.00 20.75 ? 727 TYR A CD1 1 ATOM 5048 C CD2 . TYR A 1 673 ? 129.918 526.162 57.891 1.00 18.10 ? 727 TYR A CD2 1 ATOM 5049 C CE1 . TYR A 1 673 ? 127.235 526.812 57.759 1.00 20.07 ? 727 TYR A CE1 1 ATOM 5050 C CE2 . TYR A 1 673 ? 129.070 525.832 58.944 1.00 17.96 ? 727 TYR A CE2 1 ATOM 5051 C CZ . TYR A 1 673 ? 127.724 526.143 58.864 1.00 25.37 ? 727 TYR A CZ 1 ATOM 5052 O OH . TYR A 1 673 ? 126.857 525.821 59.879 1.00 25.11 ? 727 TYR A OH 1 ATOM 5053 N N . SER A 1 674 ? 132.342 529.441 54.102 1.00 23.11 ? 728 SER A N 1 ATOM 5054 C CA . SER A 1 674 ? 133.662 529.813 53.602 1.00 23.40 ? 728 SER A CA 1 ATOM 5055 C C . SER A 1 674 ? 134.145 531.107 54.198 1.00 30.20 ? 728 SER A C 1 ATOM 5056 O O . SER A 1 674 ? 135.342 531.283 54.396 1.00 30.87 ? 728 SER A O 1 ATOM 5057 C CB . SER A 1 674 ? 133.687 529.851 52.082 1.00 25.45 ? 728 SER A CB 1 ATOM 5058 O OG . SER A 1 674 ? 133.846 528.522 51.616 1.00 39.25 ? 728 SER A OG 1 ATOM 5059 N N . LEU A 1 675 ? 133.213 532.002 54.528 1.00 26.36 ? 729 LEU A N 1 ATOM 5060 C CA . LEU A 1 675 ? 133.548 533.287 55.108 1.00 25.04 ? 729 LEU A CA 1 ATOM 5061 C C . LEU A 1 675 ? 133.679 533.271 56.617 1.00 27.45 ? 729 LEU A C 1 ATOM 5062 O O . LEU A 1 675 ? 133.936 534.330 57.206 1.00 27.56 ? 729 LEU A O 1 ATOM 5063 C CB . LEU A 1 675 ? 132.526 534.342 54.672 1.00 25.30 ? 729 LEU A CB 1 ATOM 5064 C CG . LEU A 1 675 ? 132.800 535.040 53.359 1.00 29.65 ? 729 LEU A CG 1 ATOM 5065 C CD1 . LEU A 1 675 ? 131.575 535.794 52.887 1.00 30.17 ? 729 LEU A CD1 1 ATOM 5066 C CD2 . LEU A 1 675 ? 133.990 535.950 53.474 1.00 29.25 ? 729 LEU A CD2 1 ATOM 5067 N N . LEU A 1 676 ? 133.569 532.095 57.266 1.00 22.31 ? 730 LEU A N 1 ATOM 5068 C CA . LEU A 1 676 ? 133.655 532.063 58.740 1.00 20.97 ? 730 LEU A CA 1 ATOM 5069 C C . LEU A 1 676 ? 134.908 532.726 59.316 1.00 27.14 ? 730 LEU A C 1 ATOM 5070 O O . LEU A 1 676 ? 134.744 533.487 60.269 1.00 29.48 ? 730 LEU A O 1 ATOM 5071 C CB . LEU A 1 676 ? 133.466 530.672 59.324 1.00 19.46 ? 730 LEU A CB 1 ATOM 5072 C CG . LEU A 1 676 ? 132.030 530.179 59.270 1.00 21.28 ? 730 LEU A CG 1 ATOM 5073 C CD1 . LEU A 1 676 ? 131.979 528.717 59.601 1.00 21.49 ? 730 LEU A CD1 1 ATOM 5074 C CD2 . LEU A 1 676 ? 131.102 530.978 60.188 1.00 17.26 ? 730 LEU A CD2 1 ATOM 5075 N N . PRO A 1 677 ? 136.118 532.580 58.718 1.00 22.74 ? 731 PRO A N 1 ATOM 5076 C CA . PRO A 1 677 ? 137.286 533.288 59.264 1.00 22.07 ? 731 PRO A CA 1 ATOM 5077 C C . PRO A 1 677 ? 137.111 534.796 59.254 1.00 24.31 ? 731 PRO A C 1 ATOM 5078 O O . PRO A 1 677 ? 137.553 535.456 60.189 1.00 26.54 ? 731 PRO A O 1 ATOM 5079 C CB . PRO A 1 677 ? 138.412 532.870 58.310 1.00 23.65 ? 731 PRO A CB 1 ATOM 5080 C CG . PRO A 1 677 ? 137.973 531.568 57.750 1.00 26.90 ? 731 PRO A CG 1 ATOM 5081 C CD . PRO A 1 677 ? 136.513 531.775 57.540 1.00 22.85 ? 731 PRO A CD 1 ATOM 5082 N N . PHE A 1 678 ? 136.463 535.332 58.209 1.00 17.66 ? 732 PHE A N 1 ATOM 5083 C CA . PHE A 1 678 ? 136.158 536.754 58.080 1.00 16.54 ? 732 PHE A CA 1 ATOM 5084 C C . PHE A 1 678 ? 135.146 537.198 59.159 1.00 22.29 ? 732 PHE A C 1 ATOM 5085 O O . PHE A 1 678 ? 135.386 538.152 59.889 1.00 22.26 ? 732 PHE A O 1 ATOM 5086 C CB . PHE A 1 678 ? 135.653 537.037 56.658 1.00 17.38 ? 732 PHE A CB 1 ATOM 5087 C CG . PHE A 1 678 ? 135.225 538.452 56.400 1.00 17.97 ? 732 PHE A CG 1 ATOM 5088 C CD1 . PHE A 1 678 ? 136.169 539.478 56.314 1.00 20.90 ? 732 PHE A CD1 1 ATOM 5089 C CD2 . PHE A 1 678 ? 133.887 538.769 56.248 1.00 18.23 ? 732 PHE A CD2 1 ATOM 5090 C CE1 . PHE A 1 678 ? 135.774 540.809 56.102 1.00 21.19 ? 732 PHE A CE1 1 ATOM 5091 C CE2 . PHE A 1 678 ? 133.491 540.097 56.046 1.00 22.48 ? 732 PHE A CE2 1 ATOM 5092 C CZ . PHE A 1 678 ? 134.441 541.111 55.968 1.00 20.59 ? 732 PHE A CZ 1 ATOM 5093 N N . TRP A 1 679 ? 134.043 536.474 59.289 1.00 19.67 ? 733 TRP A N 1 ATOM 5094 C CA . TRP A 1 679 ? 133.041 536.757 60.300 1.00 18.95 ? 733 TRP A CA 1 ATOM 5095 C C . TRP A 1 679 ? 133.664 536.765 61.668 1.00 24.95 ? 733 TRP A C 1 ATOM 5096 O O . TRP A 1 679 ? 133.424 537.691 62.439 1.00 25.00 ? 733 TRP A O 1 ATOM 5097 C CB . TRP A 1 679 ? 131.955 535.684 60.260 1.00 16.73 ? 733 TRP A CB 1 ATOM 5098 C CG . TRP A 1 679 ? 130.916 535.935 59.230 1.00 16.75 ? 733 TRP A CG 1 ATOM 5099 C CD1 . TRP A 1 679 ? 130.812 535.340 58.013 1.00 19.18 ? 733 TRP A CD1 1 ATOM 5100 C CD2 . TRP A 1 679 ? 129.884 536.921 59.289 1.00 16.34 ? 733 TRP A CD2 1 ATOM 5101 N NE1 . TRP A 1 679 ? 129.756 535.868 57.314 1.00 18.38 ? 733 TRP A NE1 1 ATOM 5102 C CE2 . TRP A 1 679 ? 129.176 536.857 58.066 1.00 19.90 ? 733 TRP A CE2 1 ATOM 5103 C CE3 . TRP A 1 679 ? 129.531 537.901 60.226 1.00 16.83 ? 733 TRP A CE3 1 ATOM 5104 C CZ2 . TRP A 1 679 ? 128.062 537.660 57.804 1.00 18.01 ? 733 TRP A CZ2 1 ATOM 5105 C CZ3 . TRP A 1 679 ? 128.429 538.690 59.967 1.00 18.09 ? 733 TRP A CZ3 1 ATOM 5106 C CH2 . TRP A 1 679 ? 127.714 538.576 58.760 1.00 18.27 ? 733 TRP A CH2 1 ATOM 5107 N N . TYR A 1 680 ? 134.466 535.730 61.964 1.00 21.90 ? 734 TYR A N 1 ATOM 5108 C CA . TYR A 1 680 ? 135.118 535.562 63.263 1.00 21.23 ? 734 TYR A CA 1 ATOM 5109 C C . TYR A 1 680 ? 136.042 536.741 63.578 1.00 23.94 ? 734 TYR A C 1 ATOM 5110 O O . TYR A 1 680 ? 135.973 537.277 64.672 1.00 22.72 ? 734 TYR A O 1 ATOM 5111 C CB . TYR A 1 680 ? 135.853 534.220 63.285 1.00 21.33 ? 734 TYR A CB 1 ATOM 5112 C CG . TYR A 1 680 ? 136.105 533.642 64.655 1.00 21.20 ? 734 TYR A CG 1 ATOM 5113 C CD1 . TYR A 1 680 ? 135.049 533.397 65.540 1.00 22.18 ? 734 TYR A CD1 1 ATOM 5114 C CD2 . TYR A 1 680 ? 137.379 533.222 65.026 1.00 20.64 ? 734 TYR A CD2 1 ATOM 5115 C CE1 . TYR A 1 680 ? 135.268 532.788 66.771 1.00 21.71 ? 734 TYR A CE1 1 ATOM 5116 C CE2 . TYR A 1 680 ? 137.605 532.585 66.241 1.00 21.18 ? 734 TYR A CE2 1 ATOM 5117 C CZ . TYR A 1 680 ? 136.545 532.364 67.106 1.00 28.89 ? 734 TYR A CZ 1 ATOM 5118 O OH . TYR A 1 680 ? 136.736 531.746 68.310 1.00 26.57 ? 734 TYR A OH 1 ATOM 5119 N N . THR A 1 681 ? 136.834 537.197 62.584 1.00 20.06 ? 735 THR A N 1 ATOM 5120 C CA . THR A 1 681 ? 137.710 538.352 62.730 1.00 18.83 ? 735 THR A CA 1 ATOM 5121 C C . THR A 1 681 ? 136.919 539.637 62.965 1.00 25.19 ? 735 THR A C 1 ATOM 5122 O O . THR A 1 681 ? 137.303 540.442 63.819 1.00 25.80 ? 735 THR A O 1 ATOM 5123 C CB . THR A 1 681 ? 138.653 538.475 61.549 1.00 22.35 ? 735 THR A CB 1 ATOM 5124 O OG1 . THR A 1 681 ? 139.352 537.237 61.332 1.00 18.66 ? 735 THR A OG1 1 ATOM 5125 C CG2 . THR A 1 681 ? 139.620 539.612 61.736 1.00 13.55 ? 735 THR A CG2 1 ATOM 5126 N N . LEU A 1 682 ? 135.817 539.837 62.230 1.00 21.17 ? 736 LEU A N 1 ATOM 5127 C CA . LEU A 1 682 ? 134.967 541.000 62.479 1.00 19.91 ? 736 LEU A CA 1 ATOM 5128 C C . LEU A 1 682 ? 134.418 540.975 63.914 1.00 23.93 ? 736 LEU A C 1 ATOM 5129 O O . LEU A 1 682 ? 134.372 542.019 64.574 1.00 22.43 ? 736 LEU A O 1 ATOM 5130 C CB . LEU A 1 682 ? 133.809 541.083 61.480 1.00 19.00 ? 736 LEU A CB 1 ATOM 5131 C CG . LEU A 1 682 ? 134.167 541.345 60.028 1.00 21.65 ? 736 LEU A CG 1 ATOM 5132 C CD1 . LEU A 1 682 ? 132.914 541.423 59.241 1.00 22.07 ? 736 LEU A CD1 1 ATOM 5133 C CD2 . LEU A 1 682 ? 134.958 542.642 59.856 1.00 16.57 ? 736 LEU A CD2 1 ATOM 5134 N N . PHE A 1 683 ? 134.023 539.792 64.412 1.00 23.24 ? 737 PHE A N 1 ATOM 5135 C CA . PHE A 1 683 ? 133.517 539.695 65.793 1.00 24.03 ? 737 PHE A CA 1 ATOM 5136 C C . PHE A 1 683 ? 134.604 539.942 66.838 1.00 27.90 ? 737 PHE A C 1 ATOM 5137 O O . PHE A 1 683 ? 134.342 540.587 67.864 1.00 29.59 ? 737 PHE A O 1 ATOM 5138 C CB . PHE A 1 683 ? 132.771 538.378 66.026 1.00 26.02 ? 737 PHE A CB 1 ATOM 5139 C CG . PHE A 1 683 ? 131.302 538.544 65.758 1.00 26.63 ? 737 PHE A CG 1 ATOM 5140 C CD1 . PHE A 1 683 ? 130.471 539.135 66.704 1.00 29.35 ? 737 PHE A CD1 1 ATOM 5141 C CD2 . PHE A 1 683 ? 130.762 538.192 64.533 1.00 28.16 ? 737 PHE A CD2 1 ATOM 5142 C CE1 . PHE A 1 683 ? 129.114 539.333 66.441 1.00 29.65 ? 737 PHE A CE1 1 ATOM 5143 C CE2 . PHE A 1 683 ? 129.401 538.399 64.264 1.00 30.74 ? 737 PHE A CE2 1 ATOM 5144 C CZ . PHE A 1 683 ? 128.580 538.939 65.230 1.00 28.26 ? 737 PHE A CZ 1 ATOM 5145 N N . TYR A 1 684 ? 135.835 539.521 66.543 1.00 22.93 ? 738 TYR A N 1 ATOM 5146 C CA . TYR A 1 684 ? 136.961 539.819 67.428 1.00 22.12 ? 738 TYR A CA 1 ATOM 5147 C C . TYR A 1 684 ? 137.207 541.336 67.475 1.00 23.57 ? 738 TYR A C 1 ATOM 5148 O O . TYR A 1 684 ? 137.414 541.889 68.549 1.00 22.49 ? 738 TYR A O 1 ATOM 5149 C CB . TYR A 1 684 ? 138.225 539.074 66.991 1.00 22.76 ? 738 TYR A CB 1 ATOM 5150 C CG . TYR A 1 684 ? 139.354 539.264 67.976 1.00 23.12 ? 738 TYR A CG 1 ATOM 5151 C CD1 . TYR A 1 684 ? 139.267 538.759 69.269 1.00 23.78 ? 738 TYR A CD1 1 ATOM 5152 C CD2 . TYR A 1 684 ? 140.487 539.990 67.632 1.00 23.79 ? 738 TYR A CD2 1 ATOM 5153 C CE1 . TYR A 1 684 ? 140.290 538.953 70.189 1.00 22.03 ? 738 TYR A CE1 1 ATOM 5154 C CE2 . TYR A 1 684 ? 141.532 540.159 68.534 1.00 25.07 ? 738 TYR A CE2 1 ATOM 5155 C CZ . TYR A 1 684 ? 141.433 539.634 69.811 1.00 30.28 ? 738 TYR A CZ 1 ATOM 5156 O OH . TYR A 1 684 ? 142.470 539.795 70.701 1.00 32.67 ? 738 TYR A OH 1 ATOM 5157 N N . GLN A 1 685 ? 137.142 542.001 66.321 1.00 19.73 ? 739 GLN A N 1 ATOM 5158 C CA . GLN A 1 685 ? 137.279 543.463 66.237 1.00 20.49 ? 739 GLN A CA 1 ATOM 5159 C C . GLN A 1 685 ? 136.163 544.163 67.003 1.00 24.74 ? 739 GLN A C 1 ATOM 5160 O O . GLN A 1 685 ? 136.432 545.154 67.676 1.00 24.04 ? 739 GLN A O 1 ATOM 5161 C CB . GLN A 1 685 ? 137.350 543.947 64.782 1.00 20.36 ? 739 GLN A CB 1 ATOM 5162 C CG . GLN A 1 685 ? 138.663 543.503 64.139 1.00 19.98 ? 739 GLN A CG 1 ATOM 5163 C CD . GLN A 1 685 ? 138.714 543.629 62.631 1.00 35.67 ? 739 GLN A CD 1 ATOM 5164 O OE1 . GLN A 1 685 ? 137.696 543.866 61.954 1.00 29.91 ? 739 GLN A OE1 1 ATOM 5165 N NE2 . GLN A 1 685 ? 139.914 543.468 62.072 1.00 16.20 ? 739 GLN A NE2 1 ATOM 5166 N N . ALA A 1 686 ? 134.940 543.618 66.966 1.00 20.59 ? 740 ALA A N 1 ATOM 5167 C CA . ALA A 1 686 ? 133.837 544.187 67.732 1.00 19.01 ? 740 ALA A CA 1 ATOM 5168 C C . ALA A 1 686 ? 134.100 544.021 69.220 1.00 24.33 ? 740 ALA A C 1 ATOM 5169 O O . ALA A 1 686 ? 133.850 544.935 69.997 1.00 25.30 ? 740 ALA A O 1 ATOM 5170 C CB . ALA A 1 686 ? 132.512 543.522 67.355 1.00 19.09 ? 740 ALA A CB 1 ATOM 5171 N N . HIS A 1 687 ? 134.569 542.843 69.615 1.00 21.54 ? 741 HIS A N 1 ATOM 5172 C CA . HIS A 1 687 ? 134.842 542.513 70.994 1.00 21.76 ? 741 HIS A CA 1 ATOM 5173 C C . HIS A 1 687 ? 135.969 543.383 71.535 1.00 27.96 ? 741 HIS A C 1 ATOM 5174 O O . HIS A 1 687 ? 135.937 543.787 72.698 1.00 28.36 ? 741 HIS A O 1 ATOM 5175 C CB . HIS A 1 687 ? 135.209 541.014 71.094 1.00 22.78 ? 741 HIS A CB 1 ATOM 5176 C CG . HIS A 1 687 ? 135.597 540.559 72.464 1.00 26.07 ? 741 HIS A CG 1 ATOM 5177 N ND1 . HIS A 1 687 ? 134.689 540.570 73.504 1.00 28.44 ? 741 HIS A ND1 1 ATOM 5178 C CD2 . HIS A 1 687 ? 136.764 540.029 72.910 1.00 27.75 ? 741 HIS A CD2 1 ATOM 5179 C CE1 . HIS A 1 687 ? 135.338 540.099 74.561 1.00 27.69 ? 741 HIS A CE1 1 ATOM 5180 N NE2 . HIS A 1 687 ? 136.586 539.748 74.250 1.00 27.85 ? 741 HIS A NE2 1 ATOM 5181 N N . LYS A 1 688 ? 136.994 543.609 70.735 1.00 24.97 ? 742 LYS A N 1 ATOM 5182 C CA . LYS A 1 688 ? 138.121 544.395 71.211 1.00 24.77 ? 742 LYS A CA 1 ATOM 5183 C C . LYS A 1 688 ? 137.886 545.901 71.178 1.00 29.54 ? 742 LYS A C 1 ATOM 5184 O O . LYS A 1 688 ? 138.296 546.596 72.130 1.00 27.96 ? 742 LYS A O 1 ATOM 5185 C CB . LYS A 1 688 ? 139.411 544.027 70.447 1.00 26.48 ? 742 LYS A CB 1 ATOM 5186 C CG . LYS A 1 688 ? 139.886 542.599 70.682 1.00 23.21 ? 742 LYS A CG 1 ATOM 5187 C CD . LYS A 1 688 ? 140.256 542.340 72.136 1.00 31.67 ? 742 LYS A CD 1 ATOM 5188 C CE . LYS A 1 688 ? 141.671 542.732 72.461 1.00 26.61 ? 742 LYS A CE 1 ATOM 5189 N NZ . LYS A 1 688 ? 141.851 542.906 73.917 1.00 23.84 ? 742 LYS A NZ 1 ATOM 5190 N N . GLU A 1 689 ? 137.254 546.412 70.081 1.00 26.54 ? 743 GLU A N 1 ATOM 5191 C CA . GLU A 1 689 ? 137.124 547.861 69.840 1.00 27.08 ? 743 GLU A CA 1 ATOM 5192 C C . GLU A 1 689 ? 135.732 548.442 69.984 1.00 32.12 ? 743 GLU A C 1 ATOM 5193 O O . GLU A 1 689 ? 135.598 549.659 70.143 1.00 31.73 ? 743 GLU A O 1 ATOM 5194 C CB . GLU A 1 689 ? 137.660 548.232 68.440 1.00 28.45 ? 743 GLU A CB 1 ATOM 5195 C CG . GLU A 1 689 ? 139.001 547.635 68.053 1.00 36.58 ? 743 GLU A CG 1 ATOM 5196 C CD . GLU A 1 689 ? 140.180 548.229 68.790 1.00 59.80 ? 743 GLU A CD 1 ATOM 5197 O OE1 . GLU A 1 689 ? 140.148 549.449 69.070 1.00 66.83 ? 743 GLU A OE1 1 ATOM 5198 O OE2 . GLU A 1 689 ? 141.127 547.474 69.108 1.00 56.59 ? 743 GLU A OE2 1 ATOM 5199 N N . GLY A 1 690 ? 134.719 547.592 69.870 1.00 27.54 ? 744 GLY A N 1 ATOM 5200 C CA . GLY A 1 690 ? 133.335 548.024 69.919 1.00 28.23 ? 744 GLY A CA 1 ATOM 5201 C C . GLY A 1 690 ? 132.804 548.511 68.580 1.00 34.13 ? 744 GLY A C 1 ATOM 5202 O O . GLY A 1 690 ? 131.792 549.215 68.534 1.00 34.33 ? 744 GLY A O 1 ATOM 5203 N N . PHE A 1 691 ? 133.465 548.131 67.482 1.00 30.14 ? 745 PHE A N 1 ATOM 5204 C CA . PHE A 1 691 ? 133.020 548.523 66.155 1.00 29.39 ? 745 PHE A CA 1 ATOM 5205 C C . PHE A 1 691 ? 132.004 547.525 65.652 1.00 31.74 ? 745 PHE A C 1 ATOM 5206 O O . PHE A 1 691 ? 132.175 546.323 65.825 1.00 31.67 ? 745 PHE A O 1 ATOM 5207 C CB . PHE A 1 691 ? 134.189 548.595 65.188 1.00 30.94 ? 745 PHE A CB 1 ATOM 5208 C CG . PHE A 1 691 ? 135.310 549.539 65.540 1.00 33.07 ? 745 PHE A CG 1 ATOM 5209 C CD1 . PHE A 1 691 ? 135.103 550.609 66.411 1.00 37.41 ? 745 PHE A CD1 1 ATOM 5210 C CD2 . PHE A 1 691 ? 136.561 549.390 64.965 1.00 35.57 ? 745 PHE A CD2 1 ATOM 5211 C CE1 . PHE A 1 691 ? 136.142 551.497 66.716 1.00 38.21 ? 745 PHE A CE1 1 ATOM 5212 C CE2 . PHE A 1 691 ? 137.587 550.293 65.242 1.00 38.80 ? 745 PHE A CE2 1 ATOM 5213 C CZ . PHE A 1 691 ? 137.375 551.339 66.117 1.00 36.86 ? 745 PHE A CZ 1 ATOM 5214 N N . PRO A 1 692 ? 130.971 547.991 64.958 1.00 26.68 ? 746 PRO A N 1 ATOM 5215 C CA . PRO A 1 692 ? 129.922 547.071 64.505 1.00 25.83 ? 746 PRO A CA 1 ATOM 5216 C C . PRO A 1 692 ? 130.384 546.150 63.394 1.00 28.52 ? 746 PRO A C 1 ATOM 5217 O O . PRO A 1 692 ? 131.211 546.535 62.563 1.00 28.04 ? 746 PRO A O 1 ATOM 5218 C CB . PRO A 1 692 ? 128.822 548.017 64.039 1.00 27.19 ? 746 PRO A CB 1 ATOM 5219 C CG . PRO A 1 692 ? 129.538 549.231 63.633 1.00 31.20 ? 746 PRO A CG 1 ATOM 5220 C CD . PRO A 1 692 ? 130.628 549.383 64.646 1.00 27.01 ? 746 PRO A CD 1 ATOM 5221 N N . VAL A 1 693 ? 129.838 544.939 63.378 1.00 22.91 ? 747 VAL A N 1 ATOM 5222 C CA . VAL A 1 693 ? 130.156 543.954 62.357 1.00 21.28 ? 747 VAL A CA 1 ATOM 5223 C C . VAL A 1 693 ? 129.462 544.312 61.031 1.00 23.90 ? 747 VAL A C 1 ATOM 5224 O O . VAL A 1 693 ? 130.126 544.435 59.994 1.00 20.63 ? 747 VAL A O 1 ATOM 5225 C CB . VAL A 1 693 ? 129.792 542.546 62.872 1.00 24.57 ? 747 VAL A CB 1 ATOM 5226 C CG1 . VAL A 1 693 ? 129.931 541.494 61.775 1.00 24.19 ? 747 VAL A CG1 1 ATOM 5227 C CG2 . VAL A 1 693 ? 130.637 542.184 64.091 1.00 23.47 ? 747 VAL A CG2 1 ATOM 5228 N N . MET A 1 694 ? 128.123 544.468 61.078 1.00 21.47 ? 748 MET A N 1 ATOM 5229 C CA . MET A 1 694 ? 127.283 544.842 59.951 1.00 21.50 ? 748 MET A CA 1 ATOM 5230 C C . MET A 1 694 ? 127.155 546.386 60.029 1.00 27.75 ? 748 MET A C 1 ATOM 5231 O O . MET A 1 694 ? 126.852 546.956 61.082 1.00 26.81 ? 748 MET A O 1 ATOM 5232 C CB . MET A 1 694 ? 125.946 544.139 60.125 1.00 24.09 ? 748 MET A CB 1 ATOM 5233 C CG . MET A 1 694 ? 125.130 544.048 58.904 1.00 27.85 ? 748 MET A CG 1 ATOM 5234 S SD . MET A 1 694 ? 123.508 543.507 59.423 1.00 32.23 ? 748 MET A SD 1 ATOM 5235 C CE . MET A 1 694 ? 122.582 543.885 58.009 1.00 28.88 ? 748 MET A CE 1 ATOM 5236 N N . ARG A 1 695 ? 127.445 547.068 58.940 1.00 26.59 ? 749 ARG A N 1 ATOM 5237 C CA . ARG A 1 695 ? 127.523 548.518 58.950 1.00 26.85 ? 749 ARG A CA 1 ATOM 5238 C C . ARG A 1 695 ? 126.715 549.201 57.900 1.00 30.99 ? 749 ARG A C 1 ATOM 5239 O O . ARG A 1 695 ? 126.752 548.766 56.741 1.00 30.66 ? 749 ARG A O 1 ATOM 5240 C CB . ARG A 1 695 ? 128.978 548.933 58.690 1.00 25.87 ? 749 ARG A CB 1 ATOM 5241 C CG . ARG A 1 695 ? 129.905 548.379 59.700 1.00 28.07 ? 749 ARG A CG 1 ATOM 5242 C CD . ARG A 1 695 ? 131.310 548.791 59.462 1.00 27.52 ? 749 ARG A CD 1 ATOM 5243 N NE . ARG A 1 695 ? 132.087 548.137 60.502 1.00 30.91 ? 749 ARG A NE 1 ATOM 5244 C CZ . ARG A 1 695 ? 133.402 548.133 60.602 1.00 32.45 ? 749 ARG A CZ 1 ATOM 5245 N NH1 . ARG A 1 695 ? 134.141 548.772 59.718 1.00 26.75 ? 749 ARG A NH1 1 ATOM 5246 N NH2 . ARG A 1 695 ? 133.990 547.491 61.595 1.00 18.95 ? 749 ARG A NH2 1 ATOM 5247 N N . PRO A 1 696 ? 126.107 550.367 58.216 1.00 26.65 ? 750 PRO A N 1 ATOM 5248 C CA . PRO A 1 696 ? 125.493 551.144 57.130 1.00 25.44 ? 750 PRO A CA 1 ATOM 5249 C C . PRO A 1 696 ? 126.620 551.697 56.256 1.00 29.13 ? 750 PRO A C 1 ATOM 5250 O O . PRO A 1 696 ? 127.725 551.880 56.746 1.00 31.02 ? 750 PRO A O 1 ATOM 5251 C CB . PRO A 1 696 ? 124.766 552.280 57.853 1.00 27.35 ? 750 PRO A CB 1 ATOM 5252 C CG . PRO A 1 696 ? 124.736 551.903 59.312 1.00 31.95 ? 750 PRO A CG 1 ATOM 5253 C CD . PRO A 1 696 ? 125.906 550.999 59.544 1.00 27.57 ? 750 PRO A CD 1 ATOM 5254 N N . LEU A 1 697 ? 126.375 551.952 54.984 1.00 24.91 ? 751 LEU A N 1 ATOM 5255 C CA . LEU A 1 697 ? 127.406 552.497 54.088 1.00 24.15 ? 751 LEU A CA 1 ATOM 5256 C C . LEU A 1 697 ? 127.928 553.855 54.560 1.00 27.76 ? 751 LEU A C 1 ATOM 5257 O O . LEU A 1 697 ? 129.102 554.160 54.352 1.00 26.41 ? 751 LEU A O 1 ATOM 5258 C CB . LEU A 1 697 ? 126.848 552.629 52.672 1.00 24.00 ? 751 LEU A CB 1 ATOM 5259 C CG . LEU A 1 697 ? 127.110 551.466 51.740 1.00 27.77 ? 751 LEU A CG 1 ATOM 5260 C CD1 . LEU A 1 697 ? 126.361 550.214 52.148 1.00 26.62 ? 751 LEU A CD1 1 ATOM 5261 C CD2 . LEU A 1 697 ? 126.760 551.846 50.333 1.00 32.27 ? 751 LEU A CD2 1 ATOM 5262 N N . TRP A 1 698 ? 127.092 554.640 55.248 1.00 24.42 ? 752 TRP A N 1 ATOM 5263 C CA . TRP A 1 698 ? 127.541 555.947 55.708 1.00 24.93 ? 752 TRP A CA 1 ATOM 5264 C C . TRP A 1 698 ? 128.630 555.880 56.769 1.00 27.86 ? 752 TRP A C 1 ATOM 5265 O O . TRP A 1 698 ? 129.366 556.856 56.946 1.00 27.13 ? 752 TRP A O 1 ATOM 5266 C CB . TRP A 1 698 ? 126.385 556.830 56.145 1.00 23.93 ? 752 TRP A CB 1 ATOM 5267 C CG . TRP A 1 698 ? 125.636 556.385 57.356 1.00 24.50 ? 752 TRP A CG 1 ATOM 5268 C CD1 . TRP A 1 698 ? 124.393 555.834 57.373 1.00 27.16 ? 752 TRP A CD1 1 ATOM 5269 C CD2 . TRP A 1 698 ? 125.993 556.622 58.731 1.00 23.93 ? 752 TRP A CD2 1 ATOM 5270 N NE1 . TRP A 1 698 ? 123.977 555.654 58.669 1.00 26.76 ? 752 TRP A NE1 1 ATOM 5271 C CE2 . TRP A 1 698 ? 124.941 556.126 59.523 1.00 27.83 ? 752 TRP A CE2 1 ATOM 5272 C CE3 . TRP A 1 698 ? 127.102 557.196 59.368 1.00 25.26 ? 752 TRP A CE3 1 ATOM 5273 C CZ2 . TRP A 1 698 ? 124.967 556.172 60.921 1.00 27.28 ? 752 TRP A CZ2 1 ATOM 5274 C CZ3 . TRP A 1 698 ? 127.133 557.233 60.755 1.00 26.95 ? 752 TRP A CZ3 1 ATOM 5275 C CH2 . TRP A 1 698 ? 126.079 556.714 61.516 1.00 27.74 ? 752 TRP A CH2 1 ATOM 5276 N N . VAL A 1 699 ? 128.764 554.721 57.437 1.00 23.56 ? 753 VAL A N 1 ATOM 5277 C CA . VAL A 1 699 ? 129.821 554.529 58.419 1.00 22.84 ? 753 VAL A CA 1 ATOM 5278 C C . VAL A 1 699 ? 131.199 554.496 57.707 1.00 30.21 ? 753 VAL A C 1 ATOM 5279 O O . VAL A 1 699 ? 132.178 555.066 58.221 1.00 29.78 ? 753 VAL A O 1 ATOM 5280 C CB . VAL A 1 699 ? 129.562 553.334 59.356 1.00 25.24 ? 753 VAL A CB 1 ATOM 5281 C CG1 . VAL A 1 699 ? 130.830 552.917 60.106 1.00 25.59 ? 753 VAL A CG1 1 ATOM 5282 C CG2 . VAL A 1 699 ? 128.426 553.632 60.330 1.00 23.62 ? 753 VAL A CG2 1 ATOM 5283 N N . GLN A 1 700 ? 131.272 553.867 56.516 1.00 27.16 ? 754 GLN A N 1 ATOM 5284 C CA A GLN A 1 700 ? 132.528 553.815 55.767 0.50 25.38 ? 754 GLN A CA 1 ATOM 5285 C CA B GLN A 1 700 ? 132.529 553.793 55.771 0.50 25.97 ? 754 GLN A CA 1 ATOM 5286 C C . GLN A 1 700 ? 132.669 555.019 54.840 1.00 30.35 ? 754 GLN A C 1 ATOM 5287 O O . GLN A 1 700 ? 133.779 555.357 54.443 1.00 32.06 ? 754 GLN A O 1 ATOM 5288 C CB A GLN A 1 700 ? 132.666 552.500 54.982 0.50 25.81 ? 754 GLN A CB 1 ATOM 5289 C CB B GLN A 1 700 ? 132.619 552.430 55.042 0.50 27.02 ? 754 GLN A CB 1 ATOM 5290 C CG A GLN A 1 700 ? 132.698 551.228 55.835 0.50 18.42 ? 754 GLN A CG 1 ATOM 5291 C CG B GLN A 1 700 ? 133.861 552.134 54.175 0.50 39.00 ? 754 GLN A CG 1 ATOM 5292 C CD A GLN A 1 700 ? 133.831 551.141 56.831 0.50 25.89 ? 754 GLN A CD 1 ATOM 5293 C CD B GLN A 1 700 ? 135.205 552.107 54.861 0.50 60.43 ? 754 GLN A CD 1 ATOM 5294 O OE1 A GLN A 1 700 ? 133.619 550.758 57.975 0.50 15.66 ? 754 GLN A OE1 1 ATOM 5295 O OE1 B GLN A 1 700 ? 135.364 551.632 55.995 0.50 53.94 ? 754 GLN A OE1 1 ATOM 5296 N NE2 A GLN A 1 700 ? 135.059 551.493 56.436 0.50 16.47 ? 754 GLN A NE2 1 ATOM 5297 N NE2 B GLN A 1 700 ? 136.222 552.567 54.140 0.50 56.06 ? 754 GLN A NE2 1 ATOM 5298 N N . TYR A 1 701 ? 131.548 555.703 54.503 1.00 26.65 ? 755 TYR A N 1 ATOM 5299 C CA . TYR A 1 701 ? 131.564 556.877 53.607 1.00 26.29 ? 755 TYR A CA 1 ATOM 5300 C C . TYR A 1 701 ? 130.871 558.046 54.278 1.00 32.27 ? 755 TYR A C 1 ATOM 5301 O O . TYR A 1 701 ? 129.808 558.479 53.831 1.00 32.74 ? 755 TYR A O 1 ATOM 5302 C CB . TYR A 1 701 ? 130.963 556.519 52.231 1.00 26.03 ? 755 TYR A CB 1 ATOM 5303 C CG . TYR A 1 701 ? 131.763 555.407 51.617 1.00 25.75 ? 755 TYR A CG 1 ATOM 5304 C CD1 . TYR A 1 701 ? 132.979 555.667 50.994 1.00 27.08 ? 755 TYR A CD1 1 ATOM 5305 C CD2 . TYR A 1 701 ? 131.410 554.072 51.827 1.00 27.45 ? 755 TYR A CD2 1 ATOM 5306 C CE1 . TYR A 1 701 ? 133.811 554.633 50.561 1.00 27.51 ? 755 TYR A CE1 1 ATOM 5307 C CE2 . TYR A 1 701 ? 132.215 553.026 51.360 1.00 29.20 ? 755 TYR A CE2 1 ATOM 5308 C CZ . TYR A 1 701 ? 133.425 553.310 50.746 1.00 31.48 ? 755 TYR A CZ 1 ATOM 5309 O OH . TYR A 1 701 ? 134.209 552.276 50.299 1.00 26.87 ? 755 TYR A OH 1 ATOM 5310 N N . PRO A 1 702 ? 131.468 558.574 55.372 1.00 28.90 ? 756 PRO A N 1 ATOM 5311 C CA . PRO A 1 702 ? 130.780 559.595 56.147 1.00 28.66 ? 756 PRO A CA 1 ATOM 5312 C C . PRO A 1 702 ? 130.469 560.890 55.414 1.00 34.76 ? 756 PRO A C 1 ATOM 5313 O O . PRO A 1 702 ? 129.517 561.573 55.796 1.00 33.96 ? 756 PRO A O 1 ATOM 5314 C CB . PRO A 1 702 ? 131.712 559.806 57.342 1.00 30.02 ? 756 PRO A CB 1 ATOM 5315 C CG . PRO A 1 702 ? 133.043 559.372 56.883 1.00 33.60 ? 756 PRO A CG 1 ATOM 5316 C CD . PRO A 1 702 ? 132.742 558.201 56.023 1.00 29.75 ? 756 PRO A CD 1 ATOM 5317 N N . GLU A 1 703 ? 131.231 561.207 54.365 1.00 31.95 ? 757 GLU A N 1 ATOM 5318 C CA . GLU A 1 703 ? 131.039 562.423 53.594 1.00 32.03 ? 757 GLU A CA 1 ATOM 5319 C C . GLU A 1 703 ? 130.151 562.224 52.384 1.00 37.54 ? 757 GLU A C 1 ATOM 5320 O O . GLU A 1 703 ? 129.866 563.187 51.668 1.00 38.36 ? 757 GLU A O 1 ATOM 5321 C CB . GLU A 1 703 ? 132.394 562.993 53.188 1.00 33.40 ? 757 GLU A CB 1 ATOM 5322 C CG . GLU A 1 703 ? 133.163 563.469 54.410 1.00 42.05 ? 757 GLU A CG 1 ATOM 5323 C CD . GLU A 1 703 ? 134.559 564.014 54.190 1.00 52.99 ? 757 GLU A CD 1 ATOM 5324 O OE1 . GLU A 1 703 ? 135.013 564.095 53.025 1.00 53.01 ? 757 GLU A OE1 1 ATOM 5325 O OE2 . GLU A 1 703 ? 135.196 564.377 55.201 1.00 44.58 ? 757 GLU A OE2 1 ATOM 5326 N N . ASP A 1 704 ? 129.709 560.991 52.132 1.00 32.71 ? 758 ASP A N 1 ATOM 5327 C CA . ASP A 1 704 ? 128.866 560.776 50.974 1.00 31.96 ? 758 ASP A CA 1 ATOM 5328 C C . ASP A 1 704 ? 127.414 560.865 51.400 1.00 34.70 ? 758 ASP A C 1 ATOM 5329 O O . ASP A 1 704 ? 126.847 559.884 51.868 1.00 33.34 ? 758 ASP A O 1 ATOM 5330 C CB . ASP A 1 704 ? 129.210 559.454 50.280 1.00 33.81 ? 758 ASP A CB 1 ATOM 5331 C CG . ASP A 1 704 ? 128.453 559.199 49.005 1.00 38.26 ? 758 ASP A CG 1 ATOM 5332 O OD1 . ASP A 1 704 ? 127.414 559.878 48.775 1.00 37.53 ? 758 ASP A OD1 1 ATOM 5333 O OD2 . ASP A 1 704 ? 128.842 558.281 48.276 1.00 42.18 ? 758 ASP A OD2 1 ATOM 5334 N N . MET A 1 705 ? 126.804 562.039 51.193 1.00 32.01 ? 759 MET A N 1 ATOM 5335 C CA . MET A 1 705 ? 125.432 562.339 51.602 1.00 32.17 ? 759 MET A CA 1 ATOM 5336 C C . MET A 1 705 ? 124.379 561.425 50.988 1.00 34.81 ? 759 MET A C 1 ATOM 5337 O O . MET A 1 705 ? 123.365 561.160 51.627 1.00 34.69 ? 759 MET A O 1 ATOM 5338 C CB . MET A 1 705 ? 125.108 563.799 51.367 1.00 35.25 ? 759 MET A CB 1 ATOM 5339 C CG . MET A 1 705 ? 126.031 564.709 52.146 1.00 40.63 ? 759 MET A CG 1 ATOM 5340 S SD . MET A 1 705 ? 125.543 566.436 52.198 1.00 47.18 ? 759 MET A SD 1 ATOM 5341 C CE . MET A 1 705 ? 123.775 566.227 52.857 1.00 44.06 ? 759 MET A CE 1 ATOM 5342 N N . SER A 1 706 ? 124.653 560.858 49.820 1.00 30.73 ? 760 SER A N 1 ATOM 5343 C CA . SER A 1 706 ? 123.711 559.961 49.164 1.00 29.87 ? 760 SER A CA 1 ATOM 5344 C C . SER A 1 706 ? 123.628 558.576 49.881 1.00 32.32 ? 760 SER A C 1 ATOM 5345 O O . SER A 1 706 ? 122.722 557.792 49.585 1.00 31.52 ? 760 SER A O 1 ATOM 5346 C CB . SER A 1 706 ? 124.086 559.812 47.695 1.00 31.53 ? 760 SER A CB 1 ATOM 5347 O OG . SER A 1 706 ? 125.223 558.975 47.611 1.00 42.63 ? 760 SER A OG 1 ATOM 5348 N N . THR A 1 707 ? 124.553 558.294 50.840 1.00 26.32 ? 761 THR A N 1 ATOM 5349 C CA . THR A 1 707 ? 124.548 557.019 51.590 1.00 24.82 ? 761 THR A CA 1 ATOM 5350 C C . THR A 1 707 ? 123.764 557.074 52.906 1.00 28.45 ? 761 THR A C 1 ATOM 5351 O O . THR A 1 707 ? 123.523 556.030 53.516 1.00 29.02 ? 761 THR A O 1 ATOM 5352 C CB . THR A 1 707 ? 125.991 556.517 51.907 1.00 23.80 ? 761 THR A CB 1 ATOM 5353 O OG1 . THR A 1 707 ? 126.629 557.361 52.876 1.00 22.97 ? 761 THR A OG1 1 ATOM 5354 C CG2 . THR A 1 707 ? 126.853 556.391 50.685 1.00 20.88 ? 761 THR A CG2 1 ATOM 5355 N N . PHE A 1 708 ? 123.405 558.270 53.359 1.00 22.82 ? 762 PHE A N 1 ATOM 5356 C CA . PHE A 1 708 ? 122.884 558.501 54.697 1.00 21.01 ? 762 PHE A CA 1 ATOM 5357 C C . PHE A 1 708 ? 121.612 557.737 55.036 1.00 26.39 ? 762 PHE A C 1 ATOM 5358 O O . PHE A 1 708 ? 121.398 557.439 56.209 1.00 26.82 ? 762 PHE A O 1 ATOM 5359 C CB . PHE A 1 708 ? 122.727 560.002 54.979 1.00 21.10 ? 762 PHE A CB 1 ATOM 5360 C CG . PHE A 1 708 ? 124.015 560.801 55.079 1.00 22.68 ? 762 PHE A CG 1 ATOM 5361 C CD1 . PHE A 1 708 ? 125.250 560.215 54.815 1.00 25.37 ? 762 PHE A CD1 1 ATOM 5362 C CD2 . PHE A 1 708 ? 123.995 562.141 55.445 1.00 25.26 ? 762 PHE A CD2 1 ATOM 5363 C CE1 . PHE A 1 708 ? 126.425 560.962 54.875 1.00 25.46 ? 762 PHE A CE1 1 ATOM 5364 C CE2 . PHE A 1 708 ? 125.177 562.884 55.516 1.00 27.26 ? 762 PHE A CE2 1 ATOM 5365 C CZ . PHE A 1 708 ? 126.380 562.292 55.224 1.00 24.48 ? 762 PHE A CZ 1 ATOM 5366 N N . SER A 1 709 ? 120.786 557.413 54.051 1.00 23.52 ? 763 SER A N 1 ATOM 5367 C CA . SER A 1 709 ? 119.528 556.706 54.307 1.00 23.95 ? 763 SER A CA 1 ATOM 5368 C C . SER A 1 709 ? 119.486 555.304 53.721 1.00 26.68 ? 763 SER A C 1 ATOM 5369 O O . SER A 1 709 ? 118.471 554.609 53.861 1.00 24.24 ? 763 SER A O 1 ATOM 5370 C CB . SER A 1 709 ? 118.347 557.518 53.777 1.00 28.36 ? 763 SER A CB 1 ATOM 5371 O OG . SER A 1 709 ? 118.299 558.790 54.399 1.00 42.77 ? 763 SER A OG 1 ATOM 5372 N N . ILE A 1 710 ? 120.566 554.880 53.077 1.00 24.58 ? 764 ILE A N 1 ATOM 5373 C CA . ILE A 1 710 ? 120.601 553.582 52.421 1.00 24.75 ? 764 ILE A CA 1 ATOM 5374 C C . ILE A 1 710 ? 120.340 552.453 53.388 1.00 28.78 ? 764 ILE A C 1 ATOM 5375 O O . ILE A 1 710 ? 121.056 552.303 54.376 1.00 30.34 ? 764 ILE A O 1 ATOM 5376 C CB . ILE A 1 710 ? 121.891 553.334 51.619 1.00 27.54 ? 764 ILE A CB 1 ATOM 5377 C CG1 . ILE A 1 710 ? 121.995 554.291 50.445 1.00 27.55 ? 764 ILE A CG1 1 ATOM 5378 C CG2 . ILE A 1 710 ? 121.947 551.876 51.153 1.00 28.46 ? 764 ILE A CG2 1 ATOM 5379 C CD1 . ILE A 1 710 ? 123.246 554.134 49.610 1.00 30.35 ? 764 ILE A CD1 1 ATOM 5380 N N . GLU A 1 711 ? 119.335 551.636 53.082 1.00 24.39 ? 765 GLU A N 1 ATOM 5381 C CA . GLU A 1 711 ? 119.003 550.484 53.899 1.00 22.66 ? 765 GLU A CA 1 ATOM 5382 C C . GLU A 1 711 ? 118.707 549.215 53.081 1.00 26.14 ? 765 GLU A C 1 ATOM 5383 O O . GLU A 1 711 ? 118.319 548.211 53.654 1.00 26.14 ? 765 GLU A O 1 ATOM 5384 C CB . GLU A 1 711 ? 117.878 550.831 54.873 1.00 23.51 ? 765 GLU A CB 1 ATOM 5385 C CG . GLU A 1 711 ? 116.599 551.283 54.202 1.00 27.48 ? 765 GLU A CG 1 ATOM 5386 C CD . GLU A 1 711 ? 115.473 551.552 55.174 1.00 39.32 ? 765 GLU A CD 1 ATOM 5387 O OE1 . GLU A 1 711 ? 115.709 552.247 56.187 1.00 38.79 ? 765 GLU A OE1 1 ATOM 5388 O OE2 . GLU A 1 711 ? 114.355 551.044 54.936 1.00 49.36 ? 765 GLU A OE2 1 ATOM 5389 N N . ASP A 1 712 ? 118.969 549.226 51.770 1.00 24.13 ? 766 ASP A N 1 ATOM 5390 C CA . ASP A 1 712 ? 118.790 548.040 50.914 1.00 24.21 ? 766 ASP A CA 1 ATOM 5391 C C . ASP A 1 712 ? 120.160 547.373 50.600 1.00 26.66 ? 766 ASP A C 1 ATOM 5392 O O . ASP A 1 712 ? 120.256 546.438 49.797 1.00 26.84 ? 766 ASP A O 1 ATOM 5393 C CB . ASP A 1 712 ? 117.995 548.406 49.655 1.00 25.86 ? 766 ASP A CB 1 ATOM 5394 C CG . ASP A 1 712 ? 118.638 549.400 48.711 1.00 29.89 ? 766 ASP A CG 1 ATOM 5395 O OD1 . ASP A 1 712 ? 119.738 549.936 49.037 1.00 27.66 ? 766 ASP A OD1 1 ATOM 5396 O OD2 . ASP A 1 712 ? 118.098 549.589 47.621 1.00 37.97 ? 766 ASP A OD2 1 ATOM 5397 N N . GLN A 1 713 ? 121.214 547.896 51.253 1.00 21.31 ? 767 GLN A N 1 ATOM 5398 C CA . GLN A 1 713 ? 122.599 547.419 51.201 1.00 20.69 ? 767 GLN A CA 1 ATOM 5399 C C . GLN A 1 713 ? 123.252 547.689 52.517 1.00 25.77 ? 767 GLN A C 1 ATOM 5400 O O . GLN A 1 713 ? 122.852 548.602 53.261 1.00 25.92 ? 767 GLN A O 1 ATOM 5401 C CB . GLN A 1 713 ? 123.485 548.173 50.213 1.00 21.62 ? 767 GLN A CB 1 ATOM 5402 C CG . GLN A 1 713 ? 122.841 548.640 48.985 1.00 26.38 ? 767 GLN A CG 1 ATOM 5403 C CD . GLN A 1 713 ? 123.780 549.177 47.974 1.00 24.84 ? 767 GLN A CD 1 ATOM 5404 O OE1 . GLN A 1 713 ? 123.477 549.084 46.808 1.00 16.68 ? 767 GLN A OE1 1 ATOM 5405 N NE2 . GLN A 1 713 ? 124.872 549.820 48.368 1.00 19.58 ? 767 GLN A NE2 1 ATOM 5406 N N . PHE A 1 714 ? 124.341 546.972 52.749 1.00 21.23 ? 768 PHE A N 1 ATOM 5407 C CA . PHE A 1 714 ? 125.165 547.114 53.943 1.00 19.89 ? 768 PHE A CA 1 ATOM 5408 C C . PHE A 1 714 ? 126.576 546.604 53.701 1.00 25.78 ? 768 PHE A C 1 ATOM 5409 O O . PHE A 1 714 ? 126.860 545.920 52.708 1.00 24.83 ? 768 PHE A O 1 ATOM 5410 C CB . PHE A 1 714 ? 124.524 546.422 55.166 1.00 20.12 ? 768 PHE A CB 1 ATOM 5411 C CG . PHE A 1 714 ? 124.250 544.949 54.984 1.00 20.50 ? 768 PHE A CG 1 ATOM 5412 C CD1 . PHE A 1 714 ? 123.076 544.508 54.356 1.00 23.21 ? 768 PHE A CD1 1 ATOM 5413 C CD2 . PHE A 1 714 ? 125.178 544.001 55.395 1.00 21.59 ? 768 PHE A CD2 1 ATOM 5414 C CE1 . PHE A 1 714 ? 122.846 543.137 54.144 1.00 23.79 ? 768 PHE A CE1 1 ATOM 5415 C CE2 . PHE A 1 714 ? 124.955 542.637 55.184 1.00 24.75 ? 768 PHE A CE2 1 ATOM 5416 C CZ . PHE A 1 714 ? 123.783 542.206 54.572 1.00 23.45 ? 768 PHE A CZ 1 ATOM 5417 N N . MET A 1 715 ? 127.463 546.946 54.623 1.00 24.62 ? 769 MET A N 1 ATOM 5418 C CA . MET A 1 715 ? 128.816 546.466 54.566 1.00 24.13 ? 769 MET A CA 1 ATOM 5419 C C . MET A 1 715 ? 129.132 545.544 55.721 1.00 25.05 ? 769 MET A C 1 ATOM 5420 O O . MET A 1 715 ? 128.506 545.645 56.769 1.00 22.57 ? 769 MET A O 1 ATOM 5421 C CB . MET A 1 715 ? 129.794 547.629 54.435 1.00 26.66 ? 769 MET A CB 1 ATOM 5422 C CG . MET A 1 715 ? 129.830 548.122 53.011 1.00 31.44 ? 769 MET A CG 1 ATOM 5423 S SD . MET A 1 715 ? 131.003 549.411 52.724 1.00 36.62 ? 769 MET A SD 1 ATOM 5424 C CE . MET A 1 715 ? 132.550 548.470 52.903 1.00 33.14 ? 769 MET A CE 1 ATOM 5425 N N . LEU A 1 716 ? 130.023 544.575 55.493 1.00 20.95 ? 770 LEU A N 1 ATOM 5426 C CA . LEU A 1 716 ? 130.547 543.730 56.553 1.00 20.48 ? 770 LEU A CA 1 ATOM 5427 C C . LEU A 1 716 ? 131.986 544.196 56.713 1.00 24.72 ? 770 LEU A C 1 ATOM 5428 O O . LEU A 1 716 ? 132.772 544.114 55.765 1.00 24.43 ? 770 LEU A O 1 ATOM 5429 C CB . LEU A 1 716 ? 130.448 542.248 56.218 1.00 20.23 ? 770 LEU A CB 1 ATOM 5430 C CG . LEU A 1 716 ? 129.019 541.713 56.096 1.00 22.59 ? 770 LEU A CG 1 ATOM 5431 C CD1 . LEU A 1 716 ? 129.042 540.276 55.755 1.00 21.44 ? 770 LEU A CD1 1 ATOM 5432 C CD2 . LEU A 1 716 ? 128.241 541.888 57.391 1.00 25.00 ? 770 LEU A CD2 1 ATOM 5433 N N . GLY A 1 717 ? 132.276 544.802 57.864 1.00 21.72 ? 771 GLY A N 1 ATOM 5434 C CA . GLY A 1 717 ? 133.547 545.479 58.121 1.00 22.07 ? 771 GLY A CA 1 ATOM 5435 C C . GLY A 1 717 ? 133.730 546.579 57.094 1.00 25.01 ? 771 GLY A C 1 ATOM 5436 O O . GLY A 1 717 ? 132.771 547.257 56.725 1.00 21.56 ? 771 GLY A O 1 ATOM 5437 N N . ASP A 1 718 ? 134.944 546.714 56.580 1.00 23.30 ? 772 ASP A N 1 ATOM 5438 C CA . ASP A 1 718 ? 135.260 547.675 55.525 1.00 21.99 ? 772 ASP A CA 1 ATOM 5439 C C . ASP A 1 718 ? 135.505 546.931 54.175 1.00 22.83 ? 772 ASP A C 1 ATOM 5440 O O . ASP A 1 718 ? 135.951 547.549 53.216 1.00 22.28 ? 772 ASP A O 1 ATOM 5441 C CB . ASP A 1 718 ? 136.524 548.466 55.945 1.00 23.45 ? 772 ASP A CB 1 ATOM 5442 C CG . ASP A 1 718 ? 137.859 547.781 55.724 1.00 34.77 ? 772 ASP A CG 1 ATOM 5443 O OD1 . ASP A 1 718 ? 137.939 546.552 55.899 1.00 37.17 ? 772 ASP A OD1 1 ATOM 5444 O OD2 . ASP A 1 718 ? 138.832 548.479 55.403 1.00 43.92 ? 772 ASP A OD2 1 ATOM 5445 N N . ALA A 1 719 ? 135.233 545.620 54.106 1.00 18.45 ? 773 ALA A N 1 ATOM 5446 C CA . ALA A 1 719 ? 135.641 544.807 52.964 1.00 18.04 ? 773 ALA A CA 1 ATOM 5447 C C . ALA A 1 719 ? 134.558 544.303 52.000 1.00 24.08 ? 773 ALA A C 1 ATOM 5448 O O . ALA A 1 719 ? 134.841 544.145 50.801 1.00 21.43 ? 773 ALA A O 1 ATOM 5449 C CB . ALA A 1 719 ? 136.433 543.623 53.464 1.00 18.60 ? 773 ALA A CB 1 ATOM 5450 N N . LEU A 1 720 ? 133.344 544.014 52.503 1.00 22.26 ? 774 LEU A N 1 ATOM 5451 C CA . LEU A 1 720 ? 132.295 543.452 51.649 1.00 21.29 ? 774 LEU A CA 1 ATOM 5452 C C . LEU A 1 720 ? 131.084 544.328 51.637 1.00 26.74 ? 774 LEU A C 1 ATOM 5453 O O . LEU A 1 720 ? 130.648 544.772 52.690 1.00 25.05 ? 774 LEU A O 1 ATOM 5454 C CB . LEU A 1 720 ? 131.905 542.016 52.068 1.00 19.91 ? 774 LEU A CB 1 ATOM 5455 C CG . LEU A 1 720 ? 132.992 540.951 51.957 1.00 23.80 ? 774 LEU A CG 1 ATOM 5456 C CD1 . LEU A 1 720 ? 132.460 539.599 52.395 1.00 23.85 ? 774 LEU A CD1 1 ATOM 5457 C CD2 . LEU A 1 720 ? 133.576 540.886 50.554 1.00 22.61 ? 774 LEU A CD2 1 ATOM 5458 N N . LEU A 1 721 ? 130.543 544.580 50.444 1.00 24.94 ? 775 LEU A N 1 ATOM 5459 C CA . LEU A 1 721 ? 129.330 545.369 50.299 1.00 25.79 ? 775 LEU A CA 1 ATOM 5460 C C . LEU A 1 721 ? 128.335 544.393 49.768 1.00 28.08 ? 775 LEU A C 1 ATOM 5461 O O . LEU A 1 721 ? 128.611 543.693 48.802 1.00 26.86 ? 775 LEU A O 1 ATOM 5462 C CB . LEU A 1 721 ? 129.542 546.539 49.326 1.00 26.32 ? 775 LEU A CB 1 ATOM 5463 C CG . LEU A 1 721 ? 128.391 547.497 49.110 1.00 31.13 ? 775 LEU A CG 1 ATOM 5464 C CD1 . LEU A 1 721 ? 128.920 548.845 48.695 1.00 31.94 ? 775 LEU A CD1 1 ATOM 5465 C CD2 . LEU A 1 721 ? 127.463 546.977 48.035 1.00 33.21 ? 775 LEU A CD2 1 ATOM 5466 N N . ILE A 1 722 ? 127.194 544.323 50.417 1.00 24.87 ? 776 ILE A N 1 ATOM 5467 C CA . ILE A 1 722 ? 126.152 543.347 50.112 1.00 23.86 ? 776 ILE A CA 1 ATOM 5468 C C . ILE A 1 722 ? 124.859 544.057 49.718 1.00 27.76 ? 776 ILE A C 1 ATOM 5469 O O . ILE A 1 722 ? 124.431 544.951 50.444 1.00 25.59 ? 776 ILE A O 1 ATOM 5470 C CB . ILE A 1 722 ? 125.880 542.468 51.373 1.00 25.39 ? 776 ILE A CB 1 ATOM 5471 C CG1 . ILE A 1 722 ? 127.176 542.226 52.267 1.00 24.70 ? 776 ILE A CG1 1 ATOM 5472 C CG2 . ILE A 1 722 ? 125.194 541.188 50.981 1.00 23.35 ? 776 ILE A CG2 1 ATOM 5473 C CD1 . ILE A 1 722 ? 128.282 541.428 51.649 1.00 25.95 ? 776 ILE A CD1 1 ATOM 5474 N N . HIS A 1 723 ? 124.254 543.668 48.588 1.00 25.58 ? 777 HIS A N 1 ATOM 5475 C CA . HIS A 1 723 ? 122.938 544.171 48.172 1.00 26.97 ? 777 HIS A CA 1 ATOM 5476 C C . HIS A 1 723 ? 122.076 542.936 47.882 1.00 31.74 ? 777 HIS A C 1 ATOM 5477 O O . HIS A 1 723 ? 121.929 542.528 46.724 1.00 32.47 ? 777 HIS A O 1 ATOM 5478 C CB . HIS A 1 723 ? 122.980 545.106 46.952 1.00 27.38 ? 777 HIS A CB 1 ATOM 5479 C CG . HIS A 1 723 ? 121.654 545.725 46.633 1.00 30.33 ? 777 HIS A CG 1 ATOM 5480 N ND1 . HIS A 1 723 ? 121.520 547.091 46.485 1.00 31.71 ? 777 HIS A ND1 1 ATOM 5481 C CD2 . HIS A 1 723 ? 120.430 545.158 46.507 1.00 32.02 ? 777 HIS A CD2 1 ATOM 5482 C CE1 . HIS A 1 723 ? 120.237 547.314 46.253 1.00 30.70 ? 777 HIS A CE1 1 ATOM 5483 N NE2 . HIS A 1 723 ? 119.541 546.182 46.248 1.00 31.29 ? 777 HIS A NE2 1 ATOM 5484 N N . PRO A 1 724 ? 121.532 542.293 48.926 1.00 26.00 ? 778 PRO A N 1 ATOM 5485 C CA . PRO A 1 724 ? 120.755 541.070 48.690 1.00 25.25 ? 778 PRO A CA 1 ATOM 5486 C C . PRO A 1 724 ? 119.516 541.311 47.839 1.00 29.99 ? 778 PRO A C 1 ATOM 5487 O O . PRO A 1 724 ? 118.944 542.405 47.879 1.00 27.57 ? 778 PRO A O 1 ATOM 5488 C CB . PRO A 1 724 ? 120.362 540.647 50.098 1.00 26.62 ? 778 PRO A CB 1 ATOM 5489 C CG . PRO A 1 724 ? 121.436 541.228 50.968 1.00 30.21 ? 778 PRO A CG 1 ATOM 5490 C CD . PRO A 1 724 ? 121.644 542.580 50.370 1.00 25.98 ? 778 PRO A CD 1 ATOM 5491 N N . VAL A 1 725 ? 119.117 540.298 47.042 1.00 27.64 ? 779 VAL A N 1 ATOM 5492 C CA . VAL A 1 725 ? 117.901 540.436 46.237 1.00 26.93 ? 779 VAL A CA 1 ATOM 5493 C C . VAL A 1 725 ? 116.737 540.322 47.193 1.00 31.72 ? 779 VAL A C 1 ATOM 5494 O O . VAL A 1 725 ? 116.687 539.371 47.988 1.00 30.30 ? 779 VAL A O 1 ATOM 5495 C CB . VAL A 1 725 ? 117.812 539.432 45.074 1.00 30.24 ? 779 VAL A CB 1 ATOM 5496 C CG1 . VAL A 1 725 ? 116.484 539.561 44.331 1.00 30.13 ? 779 VAL A CG1 1 ATOM 5497 C CG2 . VAL A 1 725 ? 118.970 539.626 44.111 1.00 29.49 ? 779 VAL A CG2 1 ATOM 5498 N N . SER A 1 726 ? 115.836 541.331 47.170 1.00 27.98 ? 780 SER A N 1 ATOM 5499 C CA . SER A 1 726 ? 114.710 541.342 48.095 1.00 26.21 ? 780 SER A CA 1 ATOM 5500 C C . SER A 1 726 ? 113.364 541.615 47.437 1.00 27.05 ? 780 SER A C 1 ATOM 5501 O O . SER A 1 726 ? 112.461 542.111 48.092 1.00 25.96 ? 780 SER A O 1 ATOM 5502 C CB . SER A 1 726 ? 114.984 542.315 49.232 1.00 30.15 ? 780 SER A CB 1 ATOM 5503 O OG . SER A 1 726 ? 115.069 543.658 48.781 1.00 36.91 ? 780 SER A OG 1 ATOM 5504 N N . ASP A 1 727 ? 113.221 541.285 46.142 1.00 23.21 ? 781 ASP A N 1 ATOM 5505 C CA . ASP A 1 727 ? 111.932 541.401 45.443 1.00 22.24 ? 781 ASP A CA 1 ATOM 5506 C C . ASP A 1 727 ? 111.643 540.142 44.666 1.00 27.81 ? 781 ASP A C 1 ATOM 5507 O O . ASP A 1 727 ? 112.570 539.547 44.108 1.00 28.91 ? 781 ASP A O 1 ATOM 5508 C CB . ASP A 1 727 ? 111.894 542.609 44.523 1.00 22.45 ? 781 ASP A CB 1 ATOM 5509 C CG . ASP A 1 727 ? 111.974 543.911 45.282 1.00 24.41 ? 781 ASP A CG 1 ATOM 5510 O OD1 . ASP A 1 727 ? 110.942 544.361 45.784 1.00 24.98 ? 781 ASP A OD1 1 ATOM 5511 O OD2 . ASP A 1 727 ? 113.076 544.470 45.385 1.00 27.74 ? 781 ASP A OD2 1 ATOM 5512 N N . ALA A 1 728 ? 110.357 539.732 44.606 1.00 24.27 ? 782 ALA A N 1 ATOM 5513 C CA . ALA A 1 728 ? 109.935 538.559 43.809 1.00 23.11 ? 782 ALA A CA 1 ATOM 5514 C C . ALA A 1 728 ? 110.115 538.896 42.336 1.00 28.93 ? 782 ALA A C 1 ATOM 5515 O O . ALA A 1 728 ? 109.876 540.046 41.946 1.00 29.63 ? 782 ALA A O 1 ATOM 5516 C CB . ALA A 1 728 ? 108.472 538.214 44.078 1.00 22.92 ? 782 ALA A CB 1 ATOM 5517 N N . GLY A 1 729 ? 110.572 537.919 41.551 1.00 25.56 ? 783 GLY A N 1 ATOM 5518 C CA . GLY A 1 729 ? 110.779 538.050 40.104 1.00 26.41 ? 783 GLY A CA 1 ATOM 5519 C C . GLY A 1 729 ? 111.808 539.075 39.653 1.00 30.42 ? 783 GLY A C 1 ATOM 5520 O O . GLY A 1 729 ? 111.737 539.574 38.517 1.00 31.51 ? 783 GLY A O 1 ATOM 5521 N N . ALA A 1 730 ? 112.781 539.392 40.517 1.00 24.46 ? 784 ALA A N 1 ATOM 5522 C CA . ALA A 1 730 ? 113.778 540.406 40.163 1.00 24.20 ? 784 ALA A CA 1 ATOM 5523 C C . ALA A 1 730 ? 114.794 539.844 39.210 1.00 27.32 ? 784 ALA A C 1 ATOM 5524 O O . ALA A 1 730 ? 115.178 538.692 39.349 1.00 26.99 ? 784 ALA A O 1 ATOM 5525 C CB . ALA A 1 730 ? 114.468 540.943 41.413 1.00 25.15 ? 784 ALA A CB 1 ATOM 5526 N N . HIS A 1 731 ? 115.214 540.623 38.217 1.00 24.81 ? 785 HIS A N 1 ATOM 5527 C CA . HIS A 1 731 ? 116.239 540.147 37.269 1.00 24.45 ? 785 HIS A CA 1 ATOM 5528 C C . HIS A 1 731 ? 117.512 540.957 37.332 1.00 25.71 ? 785 HIS A C 1 ATOM 5529 O O . HIS A 1 731 ? 118.492 540.627 36.659 1.00 25.09 ? 785 HIS A O 1 ATOM 5530 C CB . HIS A 1 731 ? 115.698 540.046 35.842 1.00 25.79 ? 785 HIS A CB 1 ATOM 5531 C CG . HIS A 1 731 ? 114.623 539.025 35.757 1.00 29.82 ? 785 HIS A CG 1 ATOM 5532 N ND1 . HIS A 1 731 ? 114.903 537.665 35.892 1.00 32.44 ? 785 HIS A ND1 1 ATOM 5533 C CD2 . HIS A 1 731 ? 113.288 539.194 35.681 1.00 32.01 ? 785 HIS A CD2 1 ATOM 5534 C CE1 . HIS A 1 731 ? 113.732 537.059 35.875 1.00 32.05 ? 785 HIS A CE1 1 ATOM 5535 N NE2 . HIS A 1 731 ? 112.730 537.938 35.730 1.00 32.41 ? 785 HIS A NE2 1 ATOM 5536 N N . GLY A 1 732 ? 117.499 541.974 38.186 1.00 18.86 ? 786 GLY A N 1 ATOM 5537 C CA . GLY A 1 732 ? 118.635 542.829 38.458 1.00 17.91 ? 786 GLY A CA 1 ATOM 5538 C C . GLY A 1 732 ? 118.412 543.607 39.735 1.00 24.40 ? 786 GLY A C 1 ATOM 5539 O O . GLY A 1 732 ? 117.308 543.591 40.288 1.00 22.75 ? 786 GLY A O 1 ATOM 5540 N N . VAL A 1 733 ? 119.485 544.226 40.256 1.00 23.31 ? 787 VAL A N 1 ATOM 5541 C CA . VAL A 1 733 ? 119.433 545.131 41.413 1.00 23.93 ? 787 VAL A CA 1 ATOM 5542 C C . VAL A 1 733 ? 120.278 546.362 41.086 1.00 27.36 ? 787 VAL A C 1 ATOM 5543 O O . VAL A 1 733 ? 121.297 546.236 40.382 1.00 27.55 ? 787 VAL A O 1 ATOM 5544 C CB . VAL A 1 733 ? 119.899 544.507 42.759 1.00 28.24 ? 787 VAL A CB 1 ATOM 5545 C CG1 . VAL A 1 733 ? 118.881 543.532 43.323 1.00 28.00 ? 787 VAL A CG1 1 ATOM 5546 C CG2 . VAL A 1 733 ? 121.251 543.845 42.618 1.00 28.28 ? 787 VAL A CG2 1 ATOM 5547 N N . GLN A 1 734 ? 119.869 547.540 41.585 1.00 24.28 ? 788 GLN A N 1 ATOM 5548 C CA . GLN A 1 734 ? 120.658 548.765 41.470 1.00 25.75 ? 788 GLN A CA 1 ATOM 5549 C C . GLN A 1 734 ? 121.602 548.781 42.675 1.00 32.40 ? 788 GLN A C 1 ATOM 5550 O O . GLN A 1 734 ? 121.160 548.926 43.821 1.00 32.67 ? 788 GLN A O 1 ATOM 5551 C CB . GLN A 1 734 ? 119.784 550.016 41.517 1.00 27.74 ? 788 GLN A CB 1 ATOM 5552 C CG . GLN A 1 734 ? 118.879 550.174 40.319 1.00 58.30 ? 788 GLN A CG 1 ATOM 5553 C CD . GLN A 1 734 ? 118.210 551.522 40.344 1.00 87.90 ? 788 GLN A CD 1 ATOM 5554 O OE1 . GLN A 1 734 ? 117.184 551.713 41.010 1.00 87.62 ? 788 GLN A OE1 1 ATOM 5555 N NE2 . GLN A 1 734 ? 118.777 552.487 39.620 1.00 75.83 ? 788 GLN A NE2 1 ATOM 5556 N N . VAL A 1 735 ? 122.893 548.627 42.420 1.00 28.99 ? 789 VAL A N 1 ATOM 5557 C CA . VAL A 1 735 ? 123.880 548.623 43.477 1.00 28.27 ? 789 VAL A CA 1 ATOM 5558 C C . VAL A 1 735 ? 124.622 549.939 43.527 1.00 33.42 ? 789 VAL A C 1 ATOM 5559 O O . VAL A 1 735 ? 125.288 550.302 42.559 1.00 34.61 ? 789 VAL A O 1 ATOM 5560 C CB . VAL A 1 735 ? 124.865 547.458 43.291 1.00 30.92 ? 789 VAL A CB 1 ATOM 5561 C CG1 . VAL A 1 735 ? 125.872 547.443 44.435 1.00 29.94 ? 789 VAL A CG1 1 ATOM 5562 C CG2 . VAL A 1 735 ? 124.123 546.131 43.212 1.00 30.54 ? 789 VAL A CG2 1 ATOM 5563 N N . TYR A 1 736 ? 124.577 550.630 44.653 1.00 30.05 ? 790 TYR A N 1 ATOM 5564 C CA . TYR A 1 736 ? 125.398 551.826 44.780 1.00 29.78 ? 790 TYR A CA 1 ATOM 5565 C C . TYR A 1 736 ? 126.794 551.461 45.336 1.00 32.38 ? 790 TYR A C 1 ATOM 5566 O O . TYR A 1 736 ? 126.909 550.928 46.437 1.00 31.69 ? 790 TYR A O 1 ATOM 5567 C CB . TYR A 1 736 ? 124.733 552.894 45.626 1.00 31.40 ? 790 TYR A CB 1 ATOM 5568 C CG . TYR A 1 736 ? 125.577 554.142 45.723 1.00 34.06 ? 790 TYR A CG 1 ATOM 5569 C CD1 . TYR A 1 736 ? 125.929 554.858 44.585 1.00 35.74 ? 790 TYR A CD1 1 ATOM 5570 C CD2 . TYR A 1 736 ? 126.047 554.597 46.951 1.00 35.72 ? 790 TYR A CD2 1 ATOM 5571 C CE1 . TYR A 1 736 ? 126.718 556.000 44.663 1.00 35.03 ? 790 TYR A CE1 1 ATOM 5572 C CE2 . TYR A 1 736 ? 126.817 555.756 47.044 1.00 36.81 ? 790 TYR A CE2 1 ATOM 5573 C CZ . TYR A 1 736 ? 127.164 556.442 45.892 1.00 37.96 ? 790 TYR A CZ 1 ATOM 5574 O OH . TYR A 1 736 ? 127.927 557.573 45.944 1.00 37.07 ? 790 TYR A OH 1 ATOM 5575 N N . LEU A 1 737 ? 127.833 551.722 44.543 1.00 27.28 ? 791 LEU A N 1 ATOM 5576 C CA . LEU A 1 737 ? 129.225 551.453 44.859 1.00 25.02 ? 791 LEU A CA 1 ATOM 5577 C C . LEU A 1 737 ? 129.879 552.800 45.108 1.00 28.17 ? 791 LEU A C 1 ATOM 5578 O O . LEU A 1 737 ? 130.185 553.538 44.174 1.00 27.10 ? 791 LEU A O 1 ATOM 5579 C CB . LEU A 1 737 ? 129.918 550.699 43.721 1.00 24.72 ? 791 LEU A CB 1 ATOM 5580 C CG . LEU A 1 737 ? 129.331 549.337 43.344 1.00 28.54 ? 791 LEU A CG 1 ATOM 5581 C CD1 . LEU A 1 737 ? 130.022 548.782 42.129 1.00 26.97 ? 791 LEU A CD1 1 ATOM 5582 C CD2 . LEU A 1 737 ? 129.371 548.377 44.527 1.00 31.06 ? 791 LEU A CD2 1 ATOM 5583 N N . PRO A 1 738 ? 130.057 553.148 46.392 1.00 25.77 ? 792 PRO A N 1 ATOM 5584 C CA . PRO A 1 738 ? 130.600 554.464 46.720 1.00 25.87 ? 792 PRO A CA 1 ATOM 5585 C C . PRO A 1 738 ? 132.113 554.540 46.630 1.00 28.85 ? 792 PRO A C 1 ATOM 5586 O O . PRO A 1 738 ? 132.791 553.533 46.370 1.00 25.28 ? 792 PRO A O 1 ATOM 5587 C CB . PRO A 1 738 ? 130.139 554.674 48.173 1.00 26.86 ? 792 PRO A CB 1 ATOM 5588 C CG . PRO A 1 738 ? 129.874 553.335 48.694 1.00 30.15 ? 792 PRO A CG 1 ATOM 5589 C CD . PRO A 1 738 ? 129.788 552.355 47.609 1.00 26.06 ? 792 PRO A CD 1 ATOM 5590 N N . GLY A 1 739 ? 132.600 555.752 46.886 1.00 27.13 ? 793 GLY A N 1 ATOM 5591 C CA . GLY A 1 739 ? 134.003 556.069 47.040 1.00 28.81 ? 793 GLY A CA 1 ATOM 5592 C C . GLY A 1 739 ? 134.672 556.681 45.840 1.00 36.26 ? 793 GLY A C 1 ATOM 5593 O O . GLY A 1 739 ? 134.781 556.041 44.799 1.00 35.92 ? 793 GLY A O 1 ATOM 5594 N N . GLN A 1 740 ? 135.149 557.919 45.991 1.00 35.87 ? 794 GLN A N 1 ATOM 5595 C CA . GLN A 1 740 ? 135.924 558.603 44.964 1.00 36.39 ? 794 GLN A CA 1 ATOM 5596 C C . GLN A 1 740 ? 137.224 557.811 44.881 1.00 44.16 ? 794 GLN A C 1 ATOM 5597 O O . GLN A 1 740 ? 137.814 557.489 45.924 1.00 43.87 ? 794 GLN A O 1 ATOM 5598 C CB . GLN A 1 740 ? 136.268 560.022 45.420 1.00 37.83 ? 794 GLN A CB 1 ATOM 5599 C CG . GLN A 1 740 ? 135.094 560.947 45.658 1.00 57.55 ? 794 GLN A CG 1 ATOM 5600 C CD . GLN A 1 740 ? 134.432 561.429 44.386 1.00 84.01 ? 794 GLN A CD 1 ATOM 5601 O OE1 . GLN A 1 740 ? 134.962 561.316 43.263 1.00 81.81 ? 794 GLN A OE1 1 ATOM 5602 N NE2 . GLN A 1 740 ? 133.249 562.003 44.546 1.00 73.49 ? 794 GLN A NE2 1 ATOM 5603 N N . GLU A 1 741 ? 137.663 557.438 43.673 1.00 43.30 ? 795 GLU A N 1 ATOM 5604 C CA . GLU A 1 741 ? 138.910 556.648 43.556 1.00 43.57 ? 795 GLU A CA 1 ATOM 5605 C C . GLU A 1 741 ? 138.893 555.283 44.336 1.00 42.47 ? 795 GLU A C 1 ATOM 5606 O O . GLU A 1 741 ? 139.951 554.755 44.678 1.00 41.43 ? 795 GLU A O 1 ATOM 5607 C CB . GLU A 1 741 ? 140.154 557.489 43.957 1.00 45.84 ? 795 GLU A CB 1 ATOM 5608 C CG . GLU A 1 741 ? 140.253 558.881 43.341 1.00 59.50 ? 795 GLU A CG 1 ATOM 5609 C CD . GLU A 1 741 ? 141.050 559.866 44.175 1.00 84.38 ? 795 GLU A CD 1 ATOM 5610 O OE1 . GLU A 1 741 ? 141.963 559.426 44.911 1.00 72.13 ? 795 GLU A OE1 1 ATOM 5611 O OE2 . GLU A 1 741 ? 140.751 561.081 44.102 1.00 86.56 ? 795 GLU A OE2 1 ATOM 5612 N N . GLU A 1 742 ? 137.711 554.736 44.617 1.00 35.85 ? 796 GLU A N 1 ATOM 5613 C CA . GLU A 1 742 ? 137.582 553.401 45.212 1.00 34.04 ? 796 GLU A CA 1 ATOM 5614 C C . GLU A 1 742 ? 137.301 552.447 44.050 1.00 34.97 ? 796 GLU A C 1 ATOM 5615 O O . GLU A 1 742 ? 136.697 552.862 43.057 1.00 31.96 ? 796 GLU A O 1 ATOM 5616 C CB . GLU A 1 742 ? 136.376 553.351 46.161 1.00 34.67 ? 796 GLU A CB 1 ATOM 5617 C CG . GLU A 1 742 ? 136.375 552.204 47.134 1.00 42.24 ? 796 GLU A CG 1 ATOM 5618 C CD . GLU A 1 742 ? 137.144 552.525 48.395 1.00 58.91 ? 796 GLU A CD 1 ATOM 5619 O OE1 . GLU A 1 742 ? 138.301 552.059 48.487 1.00 52.33 ? 796 GLU A OE1 1 ATOM 5620 O OE2 . GLU A 1 742 ? 136.610 553.235 49.281 1.00 46.48 ? 796 GLU A OE2 1 ATOM 5621 N N . VAL A 1 743 ? 137.691 551.171 44.188 1.00 30.32 ? 797 VAL A N 1 ATOM 5622 C CA . VAL A 1 743 ? 137.327 550.122 43.221 1.00 28.52 ? 797 VAL A CA 1 ATOM 5623 C C . VAL A 1 743 ? 136.668 549.022 43.978 1.00 27.34 ? 797 VAL A C 1 ATOM 5624 O O . VAL A 1 743 ? 136.940 548.826 45.161 1.00 27.20 ? 797 VAL A O 1 ATOM 5625 C CB . VAL A 1 743 ? 138.451 549.583 42.293 1.00 33.28 ? 797 VAL A CB 1 ATOM 5626 C CG1 . VAL A 1 743 ? 139.007 550.691 41.419 1.00 33.04 ? 797 VAL A CG1 1 ATOM 5627 C CG2 . VAL A 1 743 ? 139.571 548.929 43.096 1.00 33.35 ? 797 VAL A CG2 1 ATOM 5628 N N . TRP A 1 744 ? 135.805 548.304 43.291 1.00 22.75 ? 798 TRP A N 1 ATOM 5629 C CA . TRP A 1 744 ? 135.007 547.219 43.827 1.00 22.27 ? 798 TRP A CA 1 ATOM 5630 C C . TRP A 1 744 ? 135.084 546.031 42.890 1.00 25.14 ? 798 TRP A C 1 ATOM 5631 O O . TRP A 1 744 ? 134.981 546.189 41.679 1.00 26.04 ? 798 TRP A O 1 ATOM 5632 C CB . TRP A 1 744 ? 133.540 547.671 43.996 1.00 20.17 ? 798 TRP A CB 1 ATOM 5633 C CG . TRP A 1 744 ? 133.371 548.771 45.005 1.00 20.31 ? 798 TRP A CG 1 ATOM 5634 C CD1 . TRP A 1 744 ? 133.370 550.122 44.767 1.00 22.64 ? 798 TRP A CD1 1 ATOM 5635 C CD2 . TRP A 1 744 ? 133.189 548.614 46.408 1.00 19.14 ? 798 TRP A CD2 1 ATOM 5636 N NE1 . TRP A 1 744 ? 133.157 550.802 45.936 1.00 20.89 ? 798 TRP A NE1 1 ATOM 5637 C CE2 . TRP A 1 744 ? 133.048 549.903 46.959 1.00 21.98 ? 798 TRP A CE2 1 ATOM 5638 C CE3 . TRP A 1 744 ? 133.077 547.503 47.250 1.00 20.05 ? 798 TRP A CE3 1 ATOM 5639 C CZ2 . TRP A 1 744 ? 132.821 550.110 48.315 1.00 22.14 ? 798 TRP A CZ2 1 ATOM 5640 C CZ3 . TRP A 1 744 ? 132.836 547.709 48.592 1.00 21.22 ? 798 TRP A CZ3 1 ATOM 5641 C CH2 . TRP A 1 744 ? 132.741 549.001 49.120 1.00 22.06 ? 798 TRP A CH2 1 ATOM 5642 N N . TYR A 1 745 ? 135.228 544.849 43.442 1.00 20.95 ? 799 TYR A N 1 ATOM 5643 C CA . TYR A 1 745 ? 135.258 543.620 42.656 1.00 21.01 ? 799 TYR A CA 1 ATOM 5644 C C . TYR A 1 745 ? 134.040 542.778 42.932 1.00 23.55 ? 799 TYR A C 1 ATOM 5645 O O . TYR A 1 745 ? 133.752 542.464 44.087 1.00 21.79 ? 799 TYR A O 1 ATOM 5646 C CB . TYR A 1 745 ? 136.509 542.794 42.969 1.00 22.28 ? 799 TYR A CB 1 ATOM 5647 C CG . TYR A 1 745 ? 137.801 543.529 42.708 1.00 22.70 ? 799 TYR A CG 1 ATOM 5648 C CD1 . TYR A 1 745 ? 138.352 544.372 43.667 1.00 23.57 ? 799 TYR A CD1 1 ATOM 5649 C CD2 . TYR A 1 745 ? 138.466 543.392 41.498 1.00 23.46 ? 799 TYR A CD2 1 ATOM 5650 C CE1 . TYR A 1 745 ? 139.563 545.034 43.440 1.00 24.52 ? 799 TYR A CE1 1 ATOM 5651 C CE2 . TYR A 1 745 ? 139.677 544.040 41.261 1.00 24.82 ? 799 TYR A CE2 1 ATOM 5652 C CZ . TYR A 1 745 ? 140.226 544.856 42.236 1.00 32.13 ? 799 TYR A CZ 1 ATOM 5653 O OH . TYR A 1 745 ? 141.421 545.489 41.996 1.00 36.25 ? 799 TYR A OH 1 ATOM 5654 N N . ASP A 1 746 ? 133.303 542.433 41.869 1.00 20.73 ? 800 ASP A N 1 ATOM 5655 C CA . ASP A 1 746 ? 132.189 541.489 41.922 1.00 21.05 ? 800 ASP A CA 1 ATOM 5656 C C . ASP A 1 746 ? 132.848 540.167 42.335 1.00 25.70 ? 800 ASP A C 1 ATOM 5657 O O . ASP A 1 746 ? 133.703 539.651 41.626 1.00 25.31 ? 800 ASP A O 1 ATOM 5658 C CB . ASP A 1 746 ? 131.558 541.348 40.532 1.00 23.33 ? 800 ASP A CB 1 ATOM 5659 C CG . ASP A 1 746 ? 130.360 540.424 40.446 1.00 36.23 ? 800 ASP A CG 1 ATOM 5660 O OD1 . ASP A 1 746 ? 130.419 539.296 41.017 1.00 37.24 ? 800 ASP A OD1 1 ATOM 5661 O OD2 . ASP A 1 746 ? 129.379 540.805 39.782 1.00 41.72 ? 800 ASP A OD2 1 ATOM 5662 N N . ILE A 1 747 ? 132.538 539.674 43.516 1.00 24.59 ? 801 ILE A N 1 ATOM 5663 C CA . ILE A 1 747 ? 133.217 538.477 44.033 1.00 25.10 ? 801 ILE A CA 1 ATOM 5664 C C . ILE A 1 747 ? 132.966 537.178 43.218 1.00 31.22 ? 801 ILE A C 1 ATOM 5665 O O . ILE A 1 747 ? 133.742 536.234 43.336 1.00 31.72 ? 801 ILE A O 1 ATOM 5666 C CB . ILE A 1 747 ? 132.936 538.265 45.541 1.00 27.98 ? 801 ILE A CB 1 ATOM 5667 C CG1 . ILE A 1 747 ? 131.490 537.819 45.822 1.00 27.96 ? 801 ILE A CG1 1 ATOM 5668 C CG2 . ILE A 1 747 ? 133.291 539.519 46.337 1.00 27.51 ? 801 ILE A CG2 1 ATOM 5669 C CD1 . ILE A 1 747 ? 131.362 537.109 47.094 1.00 29.31 ? 801 ILE A CD1 1 ATOM 5670 N N . GLN A 1 748 ? 131.935 537.142 42.392 1.00 28.83 ? 802 GLN A N 1 ATOM 5671 C CA . GLN A 1 748 ? 131.645 535.980 41.577 1.00 28.61 ? 802 GLN A CA 1 ATOM 5672 C C . GLN A 1 748 ? 132.347 536.031 40.237 1.00 36.18 ? 802 GLN A C 1 ATOM 5673 O O . GLN A 1 748 ? 133.015 535.058 39.865 1.00 37.44 ? 802 GLN A O 1 ATOM 5674 C CB . GLN A 1 748 ? 130.136 535.797 41.421 1.00 28.85 ? 802 GLN A CB 1 ATOM 5675 C CG . GLN A 1 748 ? 129.431 535.479 42.752 1.00 39.27 ? 802 GLN A CG 1 ATOM 5676 C CD . GLN A 1 748 ? 129.950 534.258 43.510 1.00 57.75 ? 802 GLN A CD 1 ATOM 5677 O OE1 . GLN A 1 748 ? 129.896 534.197 44.750 1.00 53.73 ? 802 GLN A OE1 1 ATOM 5678 N NE2 . GLN A 1 748 ? 130.430 533.246 42.796 1.00 47.70 ? 802 GLN A NE2 1 ATOM 5679 N N . SER A 1 749 ? 132.228 537.172 39.521 1.00 32.12 ? 803 SER A N 1 ATOM 5680 C CA . SER A 1 749 ? 132.814 537.368 38.196 1.00 30.39 ? 803 SER A CA 1 ATOM 5681 C C . SER A 1 749 ? 134.223 537.955 38.202 1.00 33.45 ? 803 SER A C 1 ATOM 5682 O O . SER A 1 749 ? 134.883 537.928 37.167 1.00 32.48 ? 803 SER A O 1 ATOM 5683 C CB . SER A 1 749 ? 131.912 538.280 37.377 1.00 31.16 ? 803 SER A CB 1 ATOM 5684 O OG . SER A 1 749 ? 132.089 539.627 37.781 1.00 38.09 ? 803 SER A OG 1 ATOM 5685 N N . TYR A 1 750 ? 134.661 538.525 39.337 1.00 29.84 ? 804 TYR A N 1 ATOM 5686 C CA . TYR A 1 750 ? 135.919 539.263 39.487 1.00 30.64 ? 804 TYR A CA 1 ATOM 5687 C C . TYR A 1 750 ? 135.942 540.582 38.683 1.00 34.07 ? 804 TYR A C 1 ATOM 5688 O O . TYR A 1 750 ? 136.955 541.272 38.698 1.00 35.35 ? 804 TYR A O 1 ATOM 5689 C CB . TYR A 1 750 ? 137.172 538.425 39.216 1.00 32.16 ? 804 TYR A CB 1 ATOM 5690 C CG . TYR A 1 750 ? 137.284 537.168 40.053 1.00 35.28 ? 804 TYR A CG 1 ATOM 5691 C CD1 . TYR A 1 750 ? 137.577 537.232 41.415 1.00 36.49 ? 804 TYR A CD1 1 ATOM 5692 C CD2 . TYR A 1 750 ? 137.155 535.915 39.473 1.00 37.01 ? 804 TYR A CD2 1 ATOM 5693 C CE1 . TYR A 1 750 ? 137.693 536.081 42.184 1.00 36.05 ? 804 TYR A CE1 1 ATOM 5694 C CE2 . TYR A 1 750 ? 137.267 534.755 40.230 1.00 38.93 ? 804 TYR A CE2 1 ATOM 5695 C CZ . TYR A 1 750 ? 137.538 534.841 41.587 1.00 47.94 ? 804 TYR A CZ 1 ATOM 5696 O OH . TYR A 1 750 ? 137.637 533.683 42.328 1.00 50.21 ? 804 TYR A OH 1 ATOM 5697 N N . GLN A 1 751 ? 134.830 540.967 38.066 1.00 28.13 ? 805 GLN A N 1 ATOM 5698 C CA . GLN A 1 751 ? 134.712 542.208 37.333 1.00 27.55 ? 805 GLN A CA 1 ATOM 5699 C C . GLN A 1 751 ? 134.950 543.399 38.265 1.00 29.05 ? 805 GLN A C 1 ATOM 5700 O O . GLN A 1 751 ? 134.381 543.464 39.355 1.00 26.14 ? 805 GLN A O 1 ATOM 5701 C CB . GLN A 1 751 ? 133.323 542.261 36.688 1.00 29.44 ? 805 GLN A CB 1 ATOM 5702 C CG . GLN A 1 751 ? 132.936 543.569 36.045 1.00 49.75 ? 805 GLN A CG 1 ATOM 5703 C CD . GLN A 1 751 ? 133.692 543.805 34.790 1.00 74.96 ? 805 GLN A CD 1 ATOM 5704 O OE1 . GLN A 1 751 ? 134.606 544.632 34.739 1.00 69.21 ? 805 GLN A OE1 1 ATOM 5705 N NE2 . GLN A 1 751 ? 133.337 543.060 33.762 1.00 77.95 ? 805 GLN A NE2 1 ATOM 5706 N N . LYS A 1 752 ? 135.836 544.308 37.844 1.00 27.15 ? 806 LYS A N 1 ATOM 5707 C CA . LYS A 1 752 ? 136.200 545.492 38.601 1.00 27.02 ? 806 LYS A CA 1 ATOM 5708 C C . LYS A 1 752 ? 135.295 546.669 38.265 1.00 33.70 ? 806 LYS A C 1 ATOM 5709 O O . LYS A 1 752 ? 135.038 546.916 37.093 1.00 35.94 ? 806 LYS A O 1 ATOM 5710 C CB . LYS A 1 752 ? 137.655 545.828 38.305 1.00 28.10 ? 806 LYS A CB 1 ATOM 5711 C CG . LYS A 1 752 ? 138.217 546.978 39.124 1.00 35.37 ? 806 LYS A CG 1 ATOM 5712 C CD . LYS A 1 752 ? 139.478 547.516 38.482 1.00 44.79 ? 806 LYS A CD 1 ATOM 5713 C CE . LYS A 1 752 ? 140.703 547.193 39.305 1.00 66.87 ? 806 LYS A CE 1 ATOM 5714 N NZ . LYS A 1 752 ? 141.921 547.885 38.789 1.00 76.65 ? 806 LYS A NZ 1 ATOM 5715 N N . HIS A 1 753 ? 134.829 547.419 39.277 1.00 30.09 ? 807 HIS A N 1 ATOM 5716 C CA . HIS A 1 753 ? 134.010 548.614 39.054 1.00 30.07 ? 807 HIS A CA 1 ATOM 5717 C C . HIS A 1 753 ? 134.561 549.795 39.872 1.00 36.26 ? 807 HIS A C 1 ATOM 5718 O O . HIS A 1 753 ? 134.804 549.647 41.063 1.00 34.42 ? 807 HIS A O 1 ATOM 5719 C CB . HIS A 1 753 ? 132.525 548.368 39.421 1.00 30.55 ? 807 HIS A CB 1 ATOM 5720 C CG . HIS A 1 753 ? 131.890 547.179 38.760 1.00 33.28 ? 807 HIS A CG 1 ATOM 5721 N ND1 . HIS A 1 753 ? 131.323 547.277 37.509 1.00 34.55 ? 807 HIS A ND1 1 ATOM 5722 C CD2 . HIS A 1 753 ? 131.763 545.898 39.194 1.00 33.68 ? 807 HIS A CD2 1 ATOM 5723 C CE1 . HIS A 1 753 ? 130.838 546.075 37.239 1.00 32.91 ? 807 HIS A CE1 1 ATOM 5724 N NE2 . HIS A 1 753 ? 131.111 545.206 38.207 1.00 32.72 ? 807 HIS A NE2 1 ATOM 5725 N N . HIS A 1 754 ? 134.709 550.976 39.249 1.00 36.73 ? 808 HIS A N 1 ATOM 5726 C CA . HIS A 1 754 ? 135.157 552.198 39.938 1.00 38.00 ? 808 HIS A CA 1 ATOM 5727 C C . HIS A 1 754 ? 133.986 552.922 40.578 1.00 39.84 ? 808 HIS A C 1 ATOM 5728 O O . HIS A 1 754 ? 132.916 553.026 39.977 1.00 38.47 ? 808 HIS A O 1 ATOM 5729 C CB . HIS A 1 754 ? 135.850 553.160 38.965 1.00 40.66 ? 808 HIS A CB 1 ATOM 5730 C CG . HIS A 1 754 ? 137.166 552.654 38.471 1.00 45.74 ? 808 HIS A CG 1 ATOM 5731 N ND1 . HIS A 1 754 ? 138.355 553.061 39.054 1.00 48.34 ? 808 HIS A ND1 1 ATOM 5732 C CD2 . HIS A 1 754 ? 137.440 551.757 37.492 1.00 48.57 ? 808 HIS A CD2 1 ATOM 5733 C CE1 . HIS A 1 754 ? 139.315 552.411 38.406 1.00 48.18 ? 808 HIS A CE1 1 ATOM 5734 N NE2 . HIS A 1 754 ? 138.815 551.611 37.460 1.00 48.55 ? 808 HIS A NE2 1 ATOM 5735 N N . GLY A 1 755 ? 134.190 553.404 41.791 1.00 35.66 ? 809 GLY A N 1 ATOM 5736 C CA . GLY A 1 755 ? 133.188 554.206 42.461 1.00 34.87 ? 809 GLY A CA 1 ATOM 5737 C C . GLY A 1 755 ? 133.418 555.667 42.135 1.00 36.78 ? 809 GLY A C 1 ATOM 5738 O O . GLY A 1 755 ? 134.492 556.022 41.656 1.00 37.64 ? 809 GLY A O 1 ATOM 5739 N N . PRO A 1 756 ? 132.468 556.550 42.432 1.00 32.63 ? 810 PRO A N 1 ATOM 5740 C CA . PRO A 1 756 ? 131.126 556.225 42.907 1.00 31.79 ? 810 PRO A CA 1 ATOM 5741 C C . PRO A 1 756 ? 130.256 555.935 41.676 1.00 37.82 ? 810 PRO A C 1 ATOM 5742 O O . PRO A 1 756 ? 130.371 556.634 40.664 1.00 39.05 ? 810 PRO A O 1 ATOM 5743 C CB . PRO A 1 756 ? 130.704 557.512 43.632 1.00 33.06 ? 810 PRO A CB 1 ATOM 5744 C CG . PRO A 1 756 ? 131.357 558.622 42.852 1.00 37.89 ? 810 PRO A CG 1 ATOM 5745 C CD . PRO A 1 756 ? 132.657 558.017 42.284 1.00 34.55 ? 810 PRO A CD 1 ATOM 5746 N N . GLN A 1 757 ? 129.434 554.893 41.715 1.00 33.69 ? 811 GLN A N 1 ATOM 5747 C CA . GLN A 1 757 ? 128.472 554.636 40.633 1.00 32.34 ? 811 GLN A CA 1 ATOM 5748 C C . GLN A 1 757 ? 127.329 553.834 41.115 1.00 34.55 ? 811 GLN A C 1 ATOM 5749 O O . GLN A 1 757 ? 127.458 553.140 42.123 1.00 33.98 ? 811 GLN A O 1 ATOM 5750 C CB . GLN A 1 757 ? 129.083 553.944 39.393 1.00 33.55 ? 811 GLN A CB 1 ATOM 5751 C CG . GLN A 1 757 ? 129.700 552.594 39.676 1.00 39.01 ? 811 GLN A CG 1 ATOM 5752 C CD . GLN A 1 757 ? 130.033 551.869 38.413 1.00 55.05 ? 811 GLN A CD 1 ATOM 5753 O OE1 . GLN A 1 757 ? 129.141 551.490 37.659 1.00 53.77 ? 811 GLN A OE1 1 ATOM 5754 N NE2 . GLN A 1 757 ? 131.317 551.610 38.179 1.00 48.75 ? 811 GLN A NE2 1 ATOM 5755 N N . THR A 1 758 ? 126.202 553.911 40.386 1.00 31.69 ? 812 THR A N 1 ATOM 5756 C CA . THR A 1 758 ? 125.058 553.040 40.591 1.00 31.07 ? 812 THR A CA 1 ATOM 5757 C C . THR A 1 758 ? 125.088 552.033 39.433 1.00 35.31 ? 812 THR A C 1 ATOM 5758 O O . THR A 1 758 ? 124.988 552.411 38.266 1.00 35.76 ? 812 THR A O 1 ATOM 5759 C CB . THR A 1 758 ? 123.749 553.783 40.752 1.00 36.58 ? 812 THR A CB 1 ATOM 5760 O OG1 . THR A 1 758 ? 123.880 554.689 41.842 1.00 38.76 ? 812 THR A OG1 1 ATOM 5761 C CG2 . THR A 1 758 ? 122.599 552.832 41.068 1.00 33.39 ? 812 THR A CG2 1 ATOM 5762 N N . LEU A 1 759 ? 125.331 550.780 39.758 1.00 31.61 ? 813 LEU A N 1 ATOM 5763 C CA . LEU A 1 759 ? 125.460 549.693 38.793 1.00 32.20 ? 813 LEU A CA 1 ATOM 5764 C C . LEU A 1 759 ? 124.171 548.859 38.720 1.00 34.22 ? 813 LEU A C 1 ATOM 5765 O O . LEU A 1 759 ? 123.678 548.442 39.768 1.00 34.84 ? 813 LEU A O 1 ATOM 5766 C CB . LEU A 1 759 ? 126.662 548.805 39.253 1.00 32.92 ? 813 LEU A CB 1 ATOM 5767 C CG . LEU A 1 759 ? 126.885 547.438 38.605 1.00 38.38 ? 813 LEU A CG 1 ATOM 5768 C CD1 . LEU A 1 759 ? 127.259 547.583 37.122 1.00 39.61 ? 813 LEU A CD1 1 ATOM 5769 C CD2 . LEU A 1 759 ? 127.937 546.650 39.369 1.00 37.71 ? 813 LEU A CD2 1 ATOM 5770 N N . TYR A 1 760 ? 123.644 548.568 37.506 1.00 28.43 ? 814 TYR A N 1 ATOM 5771 C CA . TYR A 1 760 ? 122.499 547.660 37.415 1.00 28.06 ? 814 TYR A CA 1 ATOM 5772 C C . TYR A 1 760 ? 123.035 546.269 37.170 1.00 32.13 ? 814 TYR A C 1 ATOM 5773 O O . TYR A 1 760 ? 123.564 545.990 36.098 1.00 32.50 ? 814 TYR A O 1 ATOM 5774 C CB . TYR A 1 760 ? 121.469 548.049 36.356 1.00 29.38 ? 814 TYR A CB 1 ATOM 5775 C CG . TYR A 1 760 ? 120.157 547.310 36.549 1.00 29.14 ? 814 TYR A CG 1 ATOM 5776 C CD1 . TYR A 1 760 ? 119.253 547.702 37.528 1.00 31.14 ? 814 TYR A CD1 1 ATOM 5777 C CD2 . TYR A 1 760 ? 119.855 546.173 35.802 1.00 28.97 ? 814 TYR A CD2 1 ATOM 5778 C CE1 . TYR A 1 760 ? 118.055 547.015 37.726 1.00 31.20 ? 814 TYR A CE1 1 ATOM 5779 C CE2 . TYR A 1 760 ? 118.649 545.499 35.969 1.00 29.01 ? 814 TYR A CE2 1 ATOM 5780 C CZ . TYR A 1 760 ? 117.758 545.914 36.942 1.00 35.80 ? 814 TYR A CZ 1 ATOM 5781 O OH . TYR A 1 760 ? 116.577 545.240 37.119 1.00 35.32 ? 814 TYR A OH 1 ATOM 5782 N N . LEU A 1 761 ? 122.968 545.425 38.190 1.00 28.35 ? 815 LEU A N 1 ATOM 5783 C CA . LEU A 1 761 ? 123.557 544.119 38.127 1.00 28.39 ? 815 LEU A CA 1 ATOM 5784 C C . LEU A 1 761 ? 122.522 543.063 37.854 1.00 31.08 ? 815 LEU A C 1 ATOM 5785 O O . LEU A 1 761 ? 121.568 542.942 38.614 1.00 31.07 ? 815 LEU A O 1 ATOM 5786 C CB . LEU A 1 761 ? 124.319 543.832 39.435 1.00 29.25 ? 815 LEU A CB 1 ATOM 5787 C CG . LEU A 1 761 ? 124.997 542.448 39.539 1.00 35.86 ? 815 LEU A CG 1 ATOM 5788 C CD1 . LEU A 1 761 ? 126.377 542.429 38.838 1.00 36.38 ? 815 LEU A CD1 1 ATOM 5789 C CD2 . LEU A 1 761 ? 125.153 542.033 40.987 1.00 39.01 ? 815 LEU A CD2 1 ATOM 5790 N N . PRO A 1 762 ? 122.728 542.247 36.795 1.00 27.84 ? 816 PRO A N 1 ATOM 5791 C CA . PRO A 1 762 ? 121.797 541.137 36.520 1.00 26.82 ? 816 PRO A CA 1 ATOM 5792 C C . PRO A 1 762 ? 121.869 540.056 37.590 1.00 29.59 ? 816 PRO A C 1 ATOM 5793 O O . PRO A 1 762 ? 122.961 539.770 38.098 1.00 29.85 ? 816 PRO A O 1 ATOM 5794 C CB . PRO A 1 762 ? 122.275 540.590 35.167 1.00 27.76 ? 816 PRO A CB 1 ATOM 5795 C CG . PRO A 1 762 ? 123.634 541.063 35.004 1.00 31.42 ? 816 PRO A CG 1 ATOM 5796 C CD . PRO A 1 762 ? 123.819 542.299 35.797 1.00 28.07 ? 816 PRO A CD 1 ATOM 5797 N N . VAL A 1 763 ? 120.706 539.467 37.940 1.00 24.41 ? 817 VAL A N 1 ATOM 5798 C CA . VAL A 1 763 ? 120.622 538.414 38.948 1.00 22.99 ? 817 VAL A CA 1 ATOM 5799 C C . VAL A 1 763 ? 119.807 537.246 38.487 1.00 31.19 ? 817 VAL A C 1 ATOM 5800 O O . VAL A 1 763 ? 118.855 537.408 37.728 1.00 32.11 ? 817 VAL A O 1 ATOM 5801 C CB . VAL A 1 763 ? 120.127 538.899 40.356 1.00 23.38 ? 817 VAL A CB 1 ATOM 5802 C CG1 . VAL A 1 763 ? 121.053 539.936 40.952 1.00 22.39 ? 817 VAL A CG1 1 ATOM 5803 C CG2 . VAL A 1 763 ? 118.717 539.429 40.314 1.00 21.99 ? 817 VAL A CG2 1 ATOM 5804 N N . THR A 1 764 ? 120.157 536.071 39.017 1.00 29.87 ? 818 THR A N 1 ATOM 5805 C CA . THR A 1 764 ? 119.467 534.797 38.868 1.00 29.60 ? 818 THR A CA 1 ATOM 5806 C C . THR A 1 764 ? 119.090 534.395 40.288 1.00 34.48 ? 818 THR A C 1 ATOM 5807 O O . THR A 1 764 ? 119.481 535.063 41.262 1.00 35.22 ? 818 THR A O 1 ATOM 5808 C CB . THR A 1 764 ? 120.333 533.709 38.172 1.00 36.21 ? 818 THR A CB 1 ATOM 5809 O OG1 . THR A 1 764 ? 121.342 533.224 39.044 1.00 41.88 ? 818 THR A OG1 1 ATOM 5810 C CG2 . THR A 1 764 ? 121.027 534.214 36.964 1.00 33.91 ? 818 THR A CG2 1 ATOM 5811 N N . LEU A 1 765 ? 118.368 533.279 40.404 1.00 29.54 ? 819 LEU A N 1 ATOM 5812 C CA . LEU A 1 765 ? 117.912 532.761 41.666 1.00 27.54 ? 819 LEU A CA 1 ATOM 5813 C C . LEU A 1 765 ? 119.071 532.528 42.637 1.00 31.69 ? 819 LEU A C 1 ATOM 5814 O O . LEU A 1 765 ? 118.889 532.708 43.836 1.00 30.05 ? 819 LEU A O 1 ATOM 5815 C CB . LEU A 1 765 ? 117.116 531.487 41.428 1.00 26.71 ? 819 LEU A CB 1 ATOM 5816 C CG . LEU A 1 765 ? 116.505 530.863 42.675 1.00 30.79 ? 819 LEU A CG 1 ATOM 5817 C CD1 . LEU A 1 765 ? 115.364 531.691 43.224 1.00 29.62 ? 819 LEU A CD1 1 ATOM 5818 C CD2 . LEU A 1 765 ? 116.081 529.456 42.410 1.00 31.58 ? 819 LEU A CD2 1 ATOM 5819 N N . SER A 1 766 ? 120.257 532.141 42.123 1.00 29.85 ? 820 SER A N 1 ATOM 5820 C CA . SER A 1 766 ? 121.445 531.840 42.932 1.00 29.19 ? 820 SER A CA 1 ATOM 5821 C C . SER A 1 766 ? 122.322 533.025 43.259 1.00 31.02 ? 820 SER A C 1 ATOM 5822 O O . SER A 1 766 ? 123.271 532.887 44.027 1.00 30.40 ? 820 SER A O 1 ATOM 5823 C CB . SER A 1 766 ? 122.296 530.777 42.249 1.00 34.46 ? 820 SER A CB 1 ATOM 5824 O OG . SER A 1 766 ? 121.617 529.537 42.271 1.00 49.52 ? 820 SER A OG 1 ATOM 5825 N N . SER A 1 767 ? 122.046 534.171 42.665 1.00 27.13 ? 821 SER A N 1 ATOM 5826 C CA . SER A 1 767 ? 122.857 535.370 42.870 1.00 26.29 ? 821 SER A CA 1 ATOM 5827 C C . SER A 1 767 ? 122.717 535.981 44.228 1.00 29.73 ? 821 SER A C 1 ATOM 5828 O O . SER A 1 767 ? 121.598 536.155 44.710 1.00 30.87 ? 821 SER A O 1 ATOM 5829 C CB . SER A 1 767 ? 122.488 536.440 41.853 1.00 28.91 ? 821 SER A CB 1 ATOM 5830 O OG . SER A 1 767 ? 122.618 535.937 40.536 1.00 34.88 ? 821 SER A OG 1 ATOM 5831 N N . ILE A 1 768 ? 123.859 536.344 44.820 1.00 26.05 ? 822 ILE A N 1 ATOM 5832 C CA . ILE A 1 768 ? 123.965 537.159 46.023 1.00 25.19 ? 822 ILE A CA 1 ATOM 5833 C C . ILE A 1 768 ? 124.915 538.327 45.666 1.00 28.50 ? 822 ILE A C 1 ATOM 5834 O O . ILE A 1 768 ? 126.141 538.147 45.670 1.00 27.69 ? 822 ILE A O 1 ATOM 5835 C CB . ILE A 1 768 ? 124.432 536.428 47.277 1.00 27.17 ? 822 ILE A CB 1 ATOM 5836 C CG1 . ILE A 1 768 ? 123.779 535.053 47.389 1.00 26.02 ? 822 ILE A CG1 1 ATOM 5837 C CG2 . ILE A 1 768 ? 124.186 537.326 48.501 1.00 27.35 ? 822 ILE A CG2 1 ATOM 5838 C CD1 . ILE A 1 768 ? 124.106 534.321 48.661 1.00 23.59 ? 822 ILE A CD1 1 ATOM 5839 N N . PRO A 1 769 ? 124.371 539.504 45.314 1.00 24.12 ? 823 PRO A N 1 ATOM 5840 C CA . PRO A 1 769 ? 125.232 540.643 44.927 1.00 23.49 ? 823 PRO A CA 1 ATOM 5841 C C . PRO A 1 769 ? 126.163 541.097 46.046 1.00 24.82 ? 823 PRO A C 1 ATOM 5842 O O . PRO A 1 769 ? 125.719 541.674 47.039 1.00 22.81 ? 823 PRO A O 1 ATOM 5843 C CB . PRO A 1 769 ? 124.231 541.723 44.549 1.00 24.96 ? 823 PRO A CB 1 ATOM 5844 C CG . PRO A 1 769 ? 123.019 540.972 44.189 1.00 30.16 ? 823 PRO A CG 1 ATOM 5845 C CD . PRO A 1 769 ? 122.954 539.845 45.157 1.00 25.95 ? 823 PRO A CD 1 ATOM 5846 N N . VAL A 1 770 ? 127.442 540.749 45.911 1.00 20.62 ? 824 VAL A N 1 ATOM 5847 C CA . VAL A 1 770 ? 128.482 541.001 46.917 1.00 20.02 ? 824 VAL A CA 1 ATOM 5848 C C . VAL A 1 770 ? 129.682 541.491 46.180 1.00 22.99 ? 824 VAL A C 1 ATOM 5849 O O . VAL A 1 770 ? 130.097 540.904 45.179 1.00 21.18 ? 824 VAL A O 1 ATOM 5850 C CB . VAL A 1 770 ? 128.864 539.742 47.735 1.00 23.33 ? 824 VAL A CB 1 ATOM 5851 C CG1 . VAL A 1 770 ? 129.982 540.047 48.715 1.00 23.27 ? 824 VAL A CG1 1 ATOM 5852 C CG2 . VAL A 1 770 ? 127.675 539.153 48.474 1.00 22.86 ? 824 VAL A CG2 1 ATOM 5853 N N . PHE A 1 771 ? 130.239 542.574 46.693 1.00 20.49 ? 825 PHE A N 1 ATOM 5854 C CA . PHE A 1 771 ? 131.412 543.228 46.143 1.00 19.88 ? 825 PHE A CA 1 ATOM 5855 C C . PHE A 1 771 ? 132.505 543.357 47.177 1.00 24.43 ? 825 PHE A C 1 ATOM 5856 O O . PHE A 1 771 ? 132.218 543.760 48.322 1.00 25.61 ? 825 PHE A O 1 ATOM 5857 C CB . PHE A 1 771 ? 130.998 544.606 45.642 1.00 20.67 ? 825 PHE A CB 1 ATOM 5858 C CG . PHE A 1 771 ? 130.030 544.500 44.502 1.00 22.65 ? 825 PHE A CG 1 ATOM 5859 C CD1 . PHE A 1 771 ? 128.661 544.362 44.736 1.00 27.17 ? 825 PHE A CD1 1 ATOM 5860 C CD2 . PHE A 1 771 ? 130.482 544.461 43.191 1.00 24.70 ? 825 PHE A CD2 1 ATOM 5861 C CE1 . PHE A 1 771 ? 127.767 544.184 43.674 1.00 26.58 ? 825 PHE A CE1 1 ATOM 5862 C CE2 . PHE A 1 771 ? 129.589 544.300 42.136 1.00 27.43 ? 825 PHE A CE2 1 ATOM 5863 C CZ . PHE A 1 771 ? 128.239 544.157 42.384 1.00 24.80 ? 825 PHE A CZ 1 ATOM 5864 N N . GLN A 1 772 ? 133.739 542.988 46.804 1.00 20.60 ? 826 GLN A N 1 ATOM 5865 C CA . GLN A 1 772 ? 134.893 543.186 47.682 1.00 21.23 ? 826 GLN A CA 1 ATOM 5866 C C . GLN A 1 772 ? 135.566 544.538 47.393 1.00 25.45 ? 826 GLN A C 1 ATOM 5867 O O . GLN A 1 772 ? 135.863 544.860 46.237 1.00 22.55 ? 826 GLN A O 1 ATOM 5868 C CB . GLN A 1 772 ? 135.893 542.034 47.630 1.00 21.37 ? 826 GLN A CB 1 ATOM 5869 C CG . GLN A 1 772 ? 136.979 542.179 48.704 1.00 22.43 ? 826 GLN A CG 1 ATOM 5870 C CD . GLN A 1 772 ? 137.963 541.036 48.723 1.00 29.26 ? 826 GLN A CD 1 ATOM 5871 O OE1 . GLN A 1 772 ? 137.686 539.973 48.183 1.00 23.52 ? 826 GLN A OE1 1 ATOM 5872 N NE2 . GLN A 1 772 ? 139.125 541.215 49.376 1.00 16.83 ? 826 GLN A NE2 1 ATOM 5873 N N . ARG A 1 773 ? 135.830 545.301 48.445 1.00 25.43 ? 827 ARG A N 1 ATOM 5874 C CA . ARG A 1 773 ? 136.439 546.605 48.275 1.00 27.09 ? 827 ARG A CA 1 ATOM 5875 C C . ARG A 1 773 ? 137.898 546.501 47.965 1.00 33.21 ? 827 ARG A C 1 ATOM 5876 O O . ARG A 1 773 ? 138.617 545.772 48.633 1.00 34.82 ? 827 ARG A O 1 ATOM 5877 C CB . ARG A 1 773 ? 136.246 547.459 49.539 1.00 26.79 ? 827 ARG A CB 1 ATOM 5878 C CG . ARG A 1 773 ? 136.534 548.961 49.352 1.00 25.81 ? 827 ARG A CG 1 ATOM 5879 C CD . ARG A 1 773 ? 136.326 549.760 50.636 1.00 24.29 ? 827 ARG A CD 1 ATOM 5880 N NE . ARG A 1 773 ? 137.272 549.408 51.692 1.00 21.78 ? 827 ARG A NE 1 ATOM 5881 C CZ . ARG A 1 773 ? 138.494 549.917 51.819 1.00 41.45 ? 827 ARG A CZ 1 ATOM 5882 N NH1 . ARG A 1 773 ? 138.945 550.807 50.947 1.00 28.53 ? 827 ARG A NH1 1 ATOM 5883 N NH2 . ARG A 1 773 ? 139.285 549.520 52.805 1.00 34.16 ? 827 ARG A NH2 1 ATOM 5884 N N . GLY A 1 774 ? 138.339 547.286 46.998 1.00 29.81 ? 828 GLY A N 1 ATOM 5885 C CA . GLY A 1 774 ? 139.756 547.483 46.737 1.00 28.47 ? 828 GLY A CA 1 ATOM 5886 C C . GLY A 1 774 ? 140.455 547.947 48.004 1.00 30.63 ? 828 GLY A C 1 ATOM 5887 O O . GLY A 1 774 ? 139.932 548.769 48.761 1.00 30.19 ? 828 GLY A O 1 ATOM 5888 N N . GLY A 1 775 ? 141.618 547.373 48.256 1.00 27.14 ? 829 GLY A N 1 ATOM 5889 C CA . GLY A 1 775 ? 142.407 547.634 49.450 1.00 25.89 ? 829 GLY A CA 1 ATOM 5890 C C . GLY A 1 775 ? 142.171 546.698 50.611 1.00 26.39 ? 829 GLY A C 1 ATOM 5891 O O . GLY A 1 775 ? 142.664 546.961 51.705 1.00 24.95 ? 829 GLY A O 1 ATOM 5892 N N . THR A 1 776 ? 141.440 545.593 50.398 1.00 22.65 ? 830 THR A N 1 ATOM 5893 C CA . THR A 1 776 ? 141.145 544.657 51.493 1.00 21.12 ? 830 THR A CA 1 ATOM 5894 C C . THR A 1 776 ? 141.589 543.277 51.179 1.00 21.69 ? 830 THR A C 1 ATOM 5895 O O . THR A 1 776 ? 141.703 542.900 50.014 1.00 19.25 ? 830 THR A O 1 ATOM 5896 C CB . THR A 1 776 ? 139.649 544.646 51.853 1.00 23.87 ? 830 THR A CB 1 ATOM 5897 O OG1 . THR A 1 776 ? 138.897 544.190 50.735 1.00 27.24 ? 830 THR A OG1 1 ATOM 5898 C CG2 . THR A 1 776 ? 139.139 545.994 52.228 1.00 20.46 ? 830 THR A CG2 1 ATOM 5899 N N . ILE A 1 777 ? 141.778 542.503 52.238 1.00 19.76 ? 831 ILE A N 1 ATOM 5900 C CA . ILE A 1 777 ? 142.151 541.090 52.190 1.00 19.35 ? 831 ILE A CA 1 ATOM 5901 C C . ILE A 1 777 ? 141.164 540.334 53.064 1.00 24.19 ? 831 ILE A C 1 ATOM 5902 O O . ILE A 1 777 ? 141.050 540.594 54.264 1.00 24.44 ? 831 ILE A O 1 ATOM 5903 C CB . ILE A 1 777 ? 143.622 540.832 52.619 1.00 21.18 ? 831 ILE A CB 1 ATOM 5904 C CG1 . ILE A 1 777 ? 144.591 541.727 51.829 1.00 20.35 ? 831 ILE A CG1 1 ATOM 5905 C CG2 . ILE A 1 777 ? 143.958 539.325 52.523 1.00 18.98 ? 831 ILE A CG2 1 ATOM 5906 C CD1 . ILE A 1 777 ? 146.027 541.545 52.141 1.00 25.20 ? 831 ILE A CD1 1 ATOM 5907 N N . VAL A 1 778 ? 140.452 539.409 52.445 1.00 21.51 ? 832 VAL A N 1 ATOM 5908 C CA . VAL A 1 778 ? 139.413 538.602 53.073 1.00 21.30 ? 832 VAL A CA 1 ATOM 5909 C C . VAL A 1 778 ? 139.883 537.149 53.169 1.00 25.57 ? 832 VAL A C 1 ATOM 5910 O O . VAL A 1 778 ? 140.191 536.524 52.141 1.00 23.54 ? 832 VAL A O 1 ATOM 5911 C CB . VAL A 1 778 ? 138.076 538.730 52.287 1.00 24.50 ? 832 VAL A CB 1 ATOM 5912 C CG1 . VAL A 1 778 ? 137.039 537.762 52.800 1.00 24.05 ? 832 VAL A CG1 1 ATOM 5913 C CG2 . VAL A 1 778 ? 137.532 540.144 52.371 1.00 24.33 ? 832 VAL A CG2 1 ATOM 5914 N N . PRO A 1 779 ? 139.927 536.617 54.400 1.00 22.68 ? 833 PRO A N 1 ATOM 5915 C CA . PRO A 1 779 ? 140.307 535.209 54.586 1.00 23.44 ? 833 PRO A CA 1 ATOM 5916 C C . PRO A 1 779 ? 139.095 534.270 54.477 1.00 28.14 ? 833 PRO A C 1 ATOM 5917 O O . PRO A 1 779 ? 138.017 534.585 54.966 1.00 28.58 ? 833 PRO A O 1 ATOM 5918 C CB . PRO A 1 779 ? 140.860 535.202 56.009 1.00 24.92 ? 833 PRO A CB 1 ATOM 5919 C CG . PRO A 1 779 ? 140.037 536.246 56.737 1.00 27.96 ? 833 PRO A CG 1 ATOM 5920 C CD . PRO A 1 779 ? 139.600 537.263 55.689 1.00 24.40 ? 833 PRO A CD 1 ATOM 5921 N N . ARG A 1 780 ? 139.269 533.117 53.857 1.00 25.33 ? 834 ARG A N 1 ATOM 5922 C CA . ARG A 1 780 ? 138.182 532.136 53.710 1.00 24.66 ? 834 ARG A CA 1 ATOM 5923 C C . ARG A 1 780 ? 138.695 530.722 53.965 1.00 25.41 ? 834 ARG A C 1 ATOM 5924 O O . ARG A 1 780 ? 139.874 530.443 53.787 1.00 25.13 ? 834 ARG A O 1 ATOM 5925 C CB . ARG A 1 780 ? 137.564 532.186 52.277 1.00 20.45 ? 834 ARG A CB 1 ATOM 5926 C CG . ARG A 1 780 ? 136.689 533.380 51.969 1.00 17.85 ? 834 ARG A CG 1 ATOM 5927 C CD . ARG A 1 780 ? 135.931 533.145 50.666 1.00 29.47 ? 834 ARG A CD 1 ATOM 5928 N NE . ARG A 1 780 ? 134.924 534.169 50.376 1.00 26.54 ? 834 ARG A NE 1 ATOM 5929 C CZ . ARG A 1 780 ? 135.174 535.308 49.750 1.00 35.19 ? 834 ARG A CZ 1 ATOM 5930 N NH1 . ARG A 1 780 ? 136.402 535.598 49.353 1.00 27.17 ? 834 ARG A NH1 1 ATOM 5931 N NH2 . ARG A 1 780 ? 134.201 536.176 49.533 1.00 28.89 ? 834 ARG A NH2 1 ATOM 5932 N N . TRP A 1 781 ? 137.786 529.827 54.328 1.00 20.99 ? 835 TRP A N 1 ATOM 5933 C CA . TRP A 1 781 ? 138.030 528.390 54.374 1.00 19.90 ? 835 TRP A CA 1 ATOM 5934 C C . TRP A 1 781 ? 137.295 527.865 53.144 1.00 20.76 ? 835 TRP A C 1 ATOM 5935 O O . TRP A 1 781 ? 136.074 527.782 53.157 1.00 19.50 ? 835 TRP A O 1 ATOM 5936 C CB . TRP A 1 781 ? 137.448 527.745 55.631 1.00 18.63 ? 835 TRP A CB 1 ATOM 5937 C CG . TRP A 1 781 ? 138.323 527.815 56.838 1.00 18.89 ? 835 TRP A CG 1 ATOM 5938 C CD1 . TRP A 1 781 ? 139.665 527.574 56.912 1.00 21.51 ? 835 TRP A CD1 1 ATOM 5939 C CD2 . TRP A 1 781 ? 137.882 528.062 58.170 1.00 18.79 ? 835 TRP A CD2 1 ATOM 5940 N NE1 . TRP A 1 781 ? 140.100 527.733 58.213 1.00 21.55 ? 835 TRP A NE1 1 ATOM 5941 C CE2 . TRP A 1 781 ? 139.026 528.031 59.005 1.00 22.33 ? 835 TRP A CE2 1 ATOM 5942 C CE3 . TRP A 1 781 ? 136.631 528.357 58.738 1.00 20.14 ? 835 TRP A CE3 1 ATOM 5943 C CZ2 . TRP A 1 781 ? 138.952 528.238 60.376 1.00 21.45 ? 835 TRP A CZ2 1 ATOM 5944 C CZ3 . TRP A 1 781 ? 136.561 528.595 60.104 1.00 21.49 ? 835 TRP A CZ3 1 ATOM 5945 C CH2 . TRP A 1 781 ? 137.711 528.549 60.906 1.00 22.00 ? 835 TRP A CH2 1 ATOM 5946 N N . MET A 1 782 ? 138.015 527.563 52.067 1.00 18.89 ? 836 MET A N 1 ATOM 5947 C CA . MET A 1 782 ? 137.395 527.117 50.809 1.00 19.52 ? 836 MET A CA 1 ATOM 5948 C C . MET A 1 782 ? 136.895 525.665 50.841 1.00 23.62 ? 836 MET A C 1 ATOM 5949 O O . MET A 1 782 ? 136.123 525.268 49.956 1.00 23.98 ? 836 MET A O 1 ATOM 5950 C CB . MET A 1 782 ? 138.321 527.360 49.602 1.00 22.07 ? 836 MET A CB 1 ATOM 5951 C CG . MET A 1 782 ? 138.561 528.843 49.314 1.00 26.52 ? 836 MET A CG 1 ATOM 5952 S SD . MET A 1 782 ? 137.068 529.869 49.214 1.00 31.70 ? 836 MET A SD 1 ATOM 5953 C CE . MET A 1 782 ? 136.294 529.220 47.725 1.00 28.18 ? 836 MET A CE 1 ATOM 5954 N N . ARG A 1 783 ? 137.329 524.882 51.848 1.00 18.85 ? 837 ARG A N 1 ATOM 5955 C CA . ARG A 1 783 ? 136.911 523.495 52.005 1.00 19.17 ? 837 ARG A CA 1 ATOM 5956 C C . ARG A 1 783 ? 135.679 523.460 52.903 1.00 23.21 ? 837 ARG A C 1 ATOM 5957 O O . ARG A 1 783 ? 135.804 523.381 54.127 1.00 22.38 ? 837 ARG A O 1 ATOM 5958 C CB . ARG A 1 783 ? 138.036 522.655 52.619 1.00 18.60 ? 837 ARG A CB 1 ATOM 5959 C CG . ARG A 1 783 ? 139.325 522.686 51.842 1.00 22.00 ? 837 ARG A CG 1 ATOM 5960 C CD . ARG A 1 783 ? 140.455 522.048 52.623 1.00 20.26 ? 837 ARG A CD 1 ATOM 5961 N NE . ARG A 1 783 ? 141.711 522.286 51.903 1.00 33.26 ? 837 ARG A NE 1 ATOM 5962 C CZ . ARG A 1 783 ? 142.736 521.444 51.827 1.00 39.89 ? 837 ARG A CZ 1 ATOM 5963 N NH1 . ARG A 1 783 ? 142.725 520.305 52.511 1.00 22.53 ? 837 ARG A NH1 1 ATOM 5964 N NH2 . ARG A 1 783 ? 143.783 521.738 51.074 1.00 24.73 ? 837 ARG A NH2 1 ATOM 5965 N N . VAL A 1 784 ? 134.493 523.562 52.296 1.00 21.53 ? 838 VAL A N 1 ATOM 5966 C CA . VAL A 1 784 ? 133.242 523.588 53.060 1.00 22.01 ? 838 VAL A CA 1 ATOM 5967 C C . VAL A 1 784 ? 132.882 522.217 53.519 1.00 25.91 ? 838 VAL A C 1 ATOM 5968 O O . VAL A 1 784 ? 132.787 521.288 52.707 1.00 24.87 ? 838 VAL A O 1 ATOM 5969 C CB . VAL A 1 784 ? 132.073 524.263 52.310 1.00 25.09 ? 838 VAL A CB 1 ATOM 5970 C CG1 . VAL A 1 784 ? 130.781 524.230 53.136 1.00 24.29 ? 838 VAL A CG1 1 ATOM 5971 C CG2 . VAL A 1 784 ? 132.445 525.689 51.934 1.00 24.25 ? 838 VAL A CG2 1 ATOM 5972 N N . ARG A 1 785 ? 132.721 522.090 54.829 1.00 22.10 ? 839 ARG A N 1 ATOM 5973 C CA . ARG A 1 785 ? 132.379 520.819 55.430 1.00 21.53 ? 839 ARG A CA 1 ATOM 5974 C C . ARG A 1 785 ? 131.003 520.949 56.102 1.00 25.86 ? 839 ARG A C 1 ATOM 5975 O O . ARG A 1 785 ? 130.305 521.959 55.886 1.00 25.05 ? 839 ARG A O 1 ATOM 5976 C CB . ARG A 1 785 ? 133.509 520.329 56.350 1.00 18.32 ? 839 ARG A CB 1 ATOM 5977 C CG . ARG A 1 785 ? 134.886 520.220 55.654 1.00 14.38 ? 839 ARG A CG 1 ATOM 5978 C CD . ARG A 1 785 ? 135.823 519.732 56.703 1.00 33.76 ? 839 ARG A CD 1 ATOM 5979 N NE . ARG A 1 785 ? 137.279 519.747 56.481 1.00 34.46 ? 839 ARG A NE 1 ATOM 5980 C CZ . ARG A 1 785 ? 138.018 518.674 56.219 1.00 37.33 ? 839 ARG A CZ 1 ATOM 5981 N NH1 . ARG A 1 785 ? 139.338 518.744 56.270 1.00 22.84 ? 839 ARG A NH1 1 ATOM 5982 N NH2 . ARG A 1 785 ? 137.442 517.525 55.894 1.00 25.82 ? 839 ARG A NH2 1 ATOM 5983 N N . ARG A 1 786 ? 130.589 519.936 56.870 1.00 21.76 ? 840 ARG A N 1 ATOM 5984 C CA . ARG A 1 786 ? 129.222 519.855 57.409 1.00 21.37 ? 840 ARG A CA 1 ATOM 5985 C C . ARG A 1 786 ? 128.897 520.767 58.565 1.00 25.97 ? 840 ARG A C 1 ATOM 5986 O O . ARG A 1 786 ? 127.711 520.984 58.822 1.00 26.78 ? 840 ARG A O 1 ATOM 5987 C CB . ARG A 1 786 ? 128.870 518.419 57.787 1.00 21.73 ? 840 ARG A CB 1 ATOM 5988 C CG . ARG A 1 786 ? 129.302 517.993 59.172 1.00 27.77 ? 840 ARG A CG 1 ATOM 5989 C CD . ARG A 1 786 ? 128.966 516.554 59.362 1.00 31.63 ? 840 ARG A CD 1 ATOM 5990 N NE . ARG A 1 786 ? 129.943 515.714 58.678 1.00 29.20 ? 840 ARG A NE 1 ATOM 5991 C CZ . ARG A 1 786 ? 129.744 514.445 58.338 1.00 38.57 ? 840 ARG A CZ 1 ATOM 5992 N NH1 . ARG A 1 786 ? 128.577 513.858 58.583 1.00 27.76 ? 840 ARG A NH1 1 ATOM 5993 N NH2 . ARG A 1 786 ? 130.711 513.751 57.764 1.00 24.22 ? 840 ARG A NH2 1 ATOM 5994 N N . SER A 1 787 ? 129.927 521.286 59.268 1.00 22.02 ? 841 SER A N 1 ATOM 5995 C CA . SER A 1 787 ? 129.816 522.188 60.405 1.00 20.05 ? 841 SER A CA 1 ATOM 5996 C C . SER A 1 787 ? 131.144 522.880 60.619 1.00 23.94 ? 841 SER A C 1 ATOM 5997 O O . SER A 1 787 ? 132.168 522.445 60.093 1.00 22.35 ? 841 SER A O 1 ATOM 5998 C CB . SER A 1 787 ? 129.430 521.434 61.669 1.00 21.37 ? 841 SER A CB 1 ATOM 5999 O OG . SER A 1 787 ? 130.485 520.622 62.138 1.00 20.69 ? 841 SER A OG 1 ATOM 6000 N N . SER A 1 788 ? 131.125 523.960 61.412 1.00 21.15 ? 842 SER A N 1 ATOM 6001 C CA . SER A 1 788 ? 132.298 524.771 61.647 1.00 20.41 ? 842 SER A CA 1 ATOM 6002 C C . SER A 1 788 ? 133.346 524.018 62.429 1.00 27.69 ? 842 SER A C 1 ATOM 6003 O O . SER A 1 788 ? 134.526 524.180 62.144 1.00 26.86 ? 842 SER A O 1 ATOM 6004 C CB . SER A 1 788 ? 131.924 526.082 62.318 1.00 21.11 ? 842 SER A CB 1 ATOM 6005 O OG . SER A 1 788 ? 131.524 525.918 63.668 1.00 25.30 ? 842 SER A OG 1 ATOM 6006 N N . ASP A 1 789 ? 132.946 523.149 63.369 1.00 27.01 ? 843 ASP A N 1 ATOM 6007 C CA . ASP A 1 789 ? 133.954 522.359 64.107 1.00 27.55 ? 843 ASP A CA 1 ATOM 6008 C C . ASP A 1 789 ? 134.839 521.534 63.166 1.00 31.04 ? 843 ASP A C 1 ATOM 6009 O O . ASP A 1 789 ? 136.048 521.409 63.394 1.00 31.02 ? 843 ASP A O 1 ATOM 6010 C CB . ASP A 1 789 ? 133.319 521.424 65.156 1.00 28.64 ? 843 ASP A CB 1 ATOM 6011 C CG . ASP A 1 789 ? 133.161 521.996 66.557 1.00 28.48 ? 843 ASP A CG 1 ATOM 6012 O OD1 . ASP A 1 789 ? 133.486 523.179 66.766 1.00 33.76 ? 843 ASP A OD1 1 ATOM 6013 O OD2 . ASP A 1 789 ? 132.688 521.277 67.426 1.00 24.07 ? 843 ASP A OD2 1 ATOM 6014 N N . CYS A 1 790 ? 134.229 521.003 62.095 1.00 26.73 ? 844 CYS A N 1 ATOM 6015 C CA . CYS A 1 790 ? 134.916 520.216 61.077 1.00 25.48 ? 844 CYS A CA 1 ATOM 6016 C C . CYS A 1 790 ? 135.956 521.043 60.367 1.00 29.52 ? 844 CYS A C 1 ATOM 6017 O O . CYS A 1 790 ? 136.930 520.484 59.878 1.00 28.27 ? 844 CYS A O 1 ATOM 6018 C CB . CYS A 1 790 ? 133.924 519.656 60.068 1.00 25.41 ? 844 CYS A CB 1 ATOM 6019 S SG . CYS A 1 790 ? 132.740 518.480 60.745 1.00 29.65 ? 844 CYS A SG 1 ATOM 6020 N N . MET A 1 791 ? 135.702 522.355 60.216 1.00 26.16 ? 845 MET A N 1 ATOM 6021 C CA . MET A 1 791 ? 136.524 523.246 59.402 1.00 24.55 ? 845 MET A CA 1 ATOM 6022 C C . MET A 1 791 ? 137.572 524.048 60.157 1.00 31.80 ? 845 MET A C 1 ATOM 6023 O O . MET A 1 791 ? 138.443 524.673 59.543 1.00 31.59 ? 845 MET A O 1 ATOM 6024 C CB . MET A 1 791 ? 135.594 524.249 58.693 1.00 25.82 ? 845 MET A CB 1 ATOM 6025 C CG . MET A 1 791 ? 134.597 523.618 57.742 1.00 28.24 ? 845 MET A CG 1 ATOM 6026 S SD . MET A 1 791 ? 133.352 524.771 57.111 1.00 31.35 ? 845 MET A SD 1 ATOM 6027 C CE . MET A 1 791 ? 134.351 525.917 56.208 1.00 27.76 ? 845 MET A CE 1 ATOM 6028 N N . LYS A 1 792 ? 137.453 524.124 61.472 1.00 29.97 ? 846 LYS A N 1 ATOM 6029 C CA . LYS A 1 792 ? 138.195 525.117 62.215 1.00 28.92 ? 846 LYS A CA 1 ATOM 6030 C C . LYS A 1 792 ? 139.705 524.905 62.294 1.00 30.97 ? 846 LYS A C 1 ATOM 6031 O O . LYS A 1 792 ? 140.397 525.826 62.730 1.00 31.04 ? 846 LYS A O 1 ATOM 6032 C CB . LYS A 1 792 ? 137.587 525.357 63.584 1.00 31.17 ? 846 LYS A CB 1 ATOM 6033 C CG . LYS A 1 792 ? 137.766 524.232 64.573 1.00 40.37 ? 846 LYS A CG 1 ATOM 6034 C CD . LYS A 1 792 ? 137.028 524.595 65.830 1.00 44.25 ? 846 LYS A CD 1 ATOM 6035 C CE . LYS A 1 792 ? 136.997 523.466 66.824 1.00 43.19 ? 846 LYS A CE 1 ATOM 6036 N NZ . LYS A 1 792 ? 138.292 523.328 67.526 1.00 46.71 ? 846 LYS A NZ 1 ATOM 6037 N N . ASP A 1 793 ? 140.217 523.790 61.780 1.00 26.11 ? 847 ASP A N 1 ATOM 6038 C CA . ASP A 1 793 ? 141.669 523.559 61.714 1.00 25.78 ? 847 ASP A CA 1 ATOM 6039 C C . ASP A 1 793 ? 142.157 523.545 60.273 1.00 26.49 ? 847 ASP A C 1 ATOM 6040 O O . ASP A 1 793 ? 143.295 523.198 60.035 1.00 27.49 ? 847 ASP A O 1 ATOM 6041 C CB . ASP A 1 793 ? 142.053 522.237 62.423 1.00 27.64 ? 847 ASP A CB 1 ATOM 6042 C CG . ASP A 1 793 ? 141.766 522.248 63.914 1.00 41.24 ? 847 ASP A CG 1 ATOM 6043 O OD1 . ASP A 1 793 ? 142.227 523.192 64.601 1.00 39.30 ? 847 ASP A OD1 1 ATOM 6044 O OD2 . ASP A 1 793 ? 141.031 521.343 64.385 1.00 52.54 ? 847 ASP A OD2 1 ATOM 6045 N N . ASP A 1 794 ? 141.313 523.900 59.320 1.00 20.21 ? 848 ASP A N 1 ATOM 6046 C CA . ASP A 1 794 ? 141.636 523.838 57.915 1.00 19.13 ? 848 ASP A CA 1 ATOM 6047 C C . ASP A 1 794 ? 142.454 525.006 57.376 1.00 24.18 ? 848 ASP A C 1 ATOM 6048 O O . ASP A 1 794 ? 142.450 526.113 57.952 1.00 23.78 ? 848 ASP A O 1 ATOM 6049 C CB . ASP A 1 794 ? 140.336 523.700 57.102 1.00 21.00 ? 848 ASP A CB 1 ATOM 6050 C CG . ASP A 1 794 ? 139.748 522.296 57.053 1.00 29.52 ? 848 ASP A CG 1 ATOM 6051 O OD1 . ASP A 1 794 ? 140.519 521.317 57.150 1.00 36.48 ? 848 ASP A OD1 1 ATOM 6052 O OD2 . ASP A 1 794 ? 138.543 522.176 56.859 1.00 25.19 ? 848 ASP A OD2 1 ATOM 6053 N N . PRO A 1 795 ? 143.113 524.774 56.216 1.00 19.86 ? 849 PRO A N 1 ATOM 6054 C CA . PRO A 1 795 ? 143.866 525.855 55.575 1.00 19.00 ? 849 PRO A CA 1 ATOM 6055 C C . PRO A 1 795 ? 142.998 526.990 55.026 1.00 25.15 ? 849 PRO A C 1 ATOM 6056 O O . PRO A 1 795 ? 141.830 526.810 54.631 1.00 26.15 ? 849 PRO A O 1 ATOM 6057 C CB . PRO A 1 795 ? 144.662 525.133 54.489 1.00 18.94 ? 849 PRO A CB 1 ATOM 6058 C CG . PRO A 1 795 ? 143.821 523.985 54.154 1.00 24.07 ? 849 PRO A CG 1 ATOM 6059 C CD . PRO A 1 795 ? 143.260 523.514 55.455 1.00 19.75 ? 849 PRO A CD 1 ATOM 6060 N N . ILE A 1 796 ? 143.621 528.169 54.992 1.00 20.63 ? 850 ILE A N 1 ATOM 6061 C CA . ILE A 1 796 ? 143.045 529.430 54.575 1.00 19.48 ? 850 ILE A CA 1 ATOM 6062 C C . ILE A 1 796 ? 143.452 529.809 53.149 1.00 23.69 ? 850 ILE A C 1 ATOM 6063 O O . ILE A 1 796 ? 144.587 529.593 52.738 1.00 21.20 ? 850 ILE A O 1 ATOM 6064 C CB . ILE A 1 796 ? 143.516 530.534 55.586 1.00 22.17 ? 850 ILE A CB 1 ATOM 6065 C CG1 . ILE A 1 796 ? 142.945 530.310 57.004 1.00 22.98 ? 850 ILE A CG1 1 ATOM 6066 C CG2 . ILE A 1 796 ? 143.241 531.955 55.103 1.00 20.49 ? 850 ILE A CG2 1 ATOM 6067 C CD1 . ILE A 1 796 ? 141.489 530.685 57.184 1.00 22.50 ? 850 ILE A CD1 1 ATOM 6068 N N . THR A 1 797 ? 142.512 530.433 52.433 1.00 22.77 ? 851 THR A N 1 ATOM 6069 C CA . THR A 1 797 ? 142.682 531.096 51.148 1.00 23.04 ? 851 THR A CA 1 ATOM 6070 C C . THR A 1 797 ? 142.505 532.614 51.389 1.00 25.78 ? 851 THR A C 1 ATOM 6071 O O . THR A 1 797 ? 141.499 533.043 51.951 1.00 24.78 ? 851 THR A O 1 ATOM 6072 C CB . THR A 1 797 ? 141.682 530.595 50.104 1.00 25.47 ? 851 THR A CB 1 ATOM 6073 O OG1 . THR A 1 797 ? 141.902 529.209 49.882 1.00 25.79 ? 851 THR A OG1 1 ATOM 6074 C CG2 . THR A 1 797 ? 141.860 531.294 48.788 1.00 20.88 ? 851 THR A CG2 1 ATOM 6075 N N . LEU A 1 798 ? 143.464 533.410 50.950 1.00 21.92 ? 852 LEU A N 1 ATOM 6076 C CA . LEU A 1 798 ? 143.407 534.850 51.149 1.00 20.43 ? 852 LEU A CA 1 ATOM 6077 C C . LEU A 1 798 ? 142.999 535.495 49.840 1.00 24.69 ? 852 LEU A C 1 ATOM 6078 O O . LEU A 1 798 ? 143.567 535.185 48.784 1.00 24.90 ? 852 LEU A O 1 ATOM 6079 C CB . LEU A 1 798 ? 144.749 535.393 51.647 1.00 19.56 ? 852 LEU A CB 1 ATOM 6080 C CG . LEU A 1 798 ? 145.293 534.868 52.986 1.00 20.96 ? 852 LEU A CG 1 ATOM 6081 C CD1 . LEU A 1 798 ? 146.723 535.365 53.204 1.00 20.24 ? 852 LEU A CD1 1 ATOM 6082 C CD2 . LEU A 1 798 ? 144.463 535.329 54.120 1.00 20.22 ? 852 LEU A CD2 1 ATOM 6083 N N . PHE A 1 799 ? 141.956 536.340 49.902 1.00 20.91 ? 853 PHE A N 1 ATOM 6084 C CA . PHE A 1 799 ? 141.410 537.034 48.751 1.00 19.93 ? 853 PHE A CA 1 ATOM 6085 C C . PHE A 1 799 ? 141.837 538.490 48.841 1.00 26.13 ? 853 PHE A C 1 ATOM 6086 O O . PHE A 1 799 ? 141.329 539.256 49.657 1.00 25.58 ? 853 PHE A O 1 ATOM 6087 C CB . PHE A 1 799 ? 139.879 536.859 48.668 1.00 21.19 ? 853 PHE A CB 1 ATOM 6088 C CG . PHE A 1 799 ? 139.430 535.480 48.233 1.00 21.45 ? 853 PHE A CG 1 ATOM 6089 C CD1 . PHE A 1 799 ? 139.432 534.416 49.123 1.00 23.89 ? 853 PHE A CD1 1 ATOM 6090 C CD2 . PHE A 1 799 ? 139.022 535.243 46.935 1.00 22.50 ? 853 PHE A CD2 1 ATOM 6091 C CE1 . PHE A 1 799 ? 139.018 533.147 48.722 1.00 23.82 ? 853 PHE A CE1 1 ATOM 6092 C CE2 . PHE A 1 799 ? 138.625 533.969 46.535 1.00 25.14 ? 853 PHE A CE2 1 ATOM 6093 C CZ . PHE A 1 799 ? 138.643 532.927 47.428 1.00 22.78 ? 853 PHE A CZ 1 ATOM 6094 N N . VAL A 1 800 ? 142.821 538.852 48.028 1.00 23.18 ? 854 VAL A N 1 ATOM 6095 C CA . VAL A 1 800 ? 143.435 540.168 48.032 1.00 22.79 ? 854 VAL A CA 1 ATOM 6096 C C . VAL A 1 800 ? 142.836 541.012 46.908 1.00 27.85 ? 854 VAL A C 1 ATOM 6097 O O . VAL A 1 800 ? 143.055 540.718 45.723 1.00 26.14 ? 854 VAL A O 1 ATOM 6098 C CB . VAL A 1 800 ? 144.973 540.046 47.875 1.00 25.54 ? 854 VAL A CB 1 ATOM 6099 C CG1 . VAL A 1 800 ? 145.624 541.409 47.881 1.00 24.72 ? 854 VAL A CG1 1 ATOM 6100 C CG2 . VAL A 1 800 ? 145.583 539.159 48.954 1.00 25.63 ? 854 VAL A CG2 1 ATOM 6101 N N . ALA A 1 801 ? 142.105 542.074 47.276 1.00 24.93 ? 855 ALA A N 1 ATOM 6102 C CA . ALA A 1 801 ? 141.490 542.966 46.284 1.00 25.07 ? 855 ALA A CA 1 ATOM 6103 C C . ALA A 1 801 ? 142.329 544.232 46.238 1.00 28.21 ? 855 ALA A C 1 ATOM 6104 O O . ALA A 1 801 ? 142.395 544.973 47.210 1.00 26.74 ? 855 ALA A O 1 ATOM 6105 C CB . ALA A 1 801 ? 140.047 543.270 46.661 1.00 25.62 ? 855 ALA A CB 1 ATOM 6106 N N . LEU A 1 802 ? 143.060 544.421 45.151 1.00 25.65 ? 856 LEU A N 1 ATOM 6107 C CA . LEU A 1 802 ? 143.970 545.548 45.079 1.00 26.21 ? 856 LEU A CA 1 ATOM 6108 C C . LEU A 1 802 ? 143.283 546.873 44.868 1.00 28.64 ? 856 LEU A C 1 ATOM 6109 O O . LEU A 1 802 ? 142.379 546.995 44.048 1.00 29.12 ? 856 LEU A O 1 ATOM 6110 C CB . LEU A 1 802 ? 145.057 545.318 44.018 1.00 26.88 ? 856 LEU A CB 1 ATOM 6111 C CG . LEU A 1 802 ? 146.072 544.170 44.276 1.00 32.19 ? 856 LEU A CG 1 ATOM 6112 C CD1 . LEU A 1 802 ? 147.062 544.081 43.146 1.00 33.03 ? 856 LEU A CD1 1 ATOM 6113 C CD2 . LEU A 1 802 ? 146.803 544.314 45.610 1.00 31.93 ? 856 LEU A CD2 1 ATOM 6114 N N . SER A 1 803 ? 143.702 547.856 45.649 1.00 24.33 ? 857 SER A N 1 ATOM 6115 C CA . SER A 1 803 ? 143.282 549.240 45.496 1.00 24.60 ? 857 SER A CA 1 ATOM 6116 C C . SER A 1 803 ? 143.919 549.773 44.187 1.00 31.93 ? 857 SER A C 1 ATOM 6117 O O . SER A 1 803 ? 144.870 549.156 43.679 1.00 29.55 ? 857 SER A O 1 ATOM 6118 C CB . SER A 1 803 ? 143.788 550.085 46.668 1.00 25.25 ? 857 SER A CB 1 ATOM 6119 O OG . SER A 1 803 ? 145.194 550.255 46.619 1.00 32.96 ? 857 SER A OG 1 ATOM 6120 N N . PRO A 1 804 ? 143.476 550.961 43.685 1.00 32.81 ? 858 PRO A N 1 ATOM 6121 C CA . PRO A 1 804 ? 144.131 551.561 42.505 1.00 33.39 ? 858 PRO A CA 1 ATOM 6122 C C . PRO A 1 804 ? 145.631 551.840 42.703 1.00 36.33 ? 858 PRO A C 1 ATOM 6123 O O . PRO A 1 804 ? 146.380 551.876 41.731 1.00 35.97 ? 858 PRO A O 1 ATOM 6124 C CB . PRO A 1 804 ? 143.341 552.849 42.296 1.00 35.45 ? 858 PRO A CB 1 ATOM 6125 C CG . PRO A 1 804 ? 141.988 552.554 42.903 1.00 39.62 ? 858 PRO A CG 1 ATOM 6126 C CD . PRO A 1 804 ? 142.359 551.812 44.145 1.00 35.03 ? 858 PRO A CD 1 ATOM 6127 N N . GLN A 1 805 ? 146.084 551.951 43.957 1.00 32.43 ? 859 GLN A N 1 ATOM 6128 C CA . GLN A 1 805 ? 147.495 552.148 44.310 1.00 31.38 ? 859 GLN A CA 1 ATOM 6129 C C . GLN A 1 805 ? 148.241 550.805 44.424 1.00 35.49 ? 859 GLN A C 1 ATOM 6130 O O . GLN A 1 805 ? 149.423 550.783 44.776 1.00 35.77 ? 859 GLN A O 1 ATOM 6131 C CB . GLN A 1 805 ? 147.612 552.898 45.640 1.00 32.71 ? 859 GLN A CB 1 ATOM 6132 C CG . GLN A 1 805 ? 147.003 554.310 45.665 1.00 53.42 ? 859 GLN A CG 1 ATOM 6133 C CD . GLN A 1 805 ? 145.495 554.331 45.837 1.00 67.59 ? 859 GLN A CD 1 ATOM 6134 O OE1 . GLN A 1 805 ? 144.915 553.650 46.697 1.00 57.93 ? 859 GLN A OE1 1 ATOM 6135 N NE2 . GLN A 1 805 ? 144.829 555.115 44.998 1.00 65.39 ? 859 GLN A NE2 1 ATOM 6136 N N . GLY A 1 806 ? 147.541 549.699 44.168 1.00 30.65 ? 860 GLY A N 1 ATOM 6137 C CA . GLY A 1 806 ? 148.107 548.359 44.254 1.00 29.72 ? 860 GLY A CA 1 ATOM 6138 C C . GLY A 1 806 ? 148.409 547.945 45.671 1.00 33.56 ? 860 GLY A C 1 ATOM 6139 O O . GLY A 1 806 ? 149.436 547.335 45.934 1.00 35.45 ? 860 GLY A O 1 ATOM 6140 N N . THR A 1 807 ? 147.546 548.314 46.596 1.00 28.93 ? 861 THR A N 1 ATOM 6141 C CA . THR A 1 807 ? 147.701 547.997 48.016 1.00 28.30 ? 861 THR A CA 1 ATOM 6142 C C . THR A 1 807 ? 146.449 547.308 48.546 1.00 29.78 ? 861 THR A C 1 ATOM 6143 O O . THR A 1 807 ? 145.359 547.448 47.990 1.00 29.61 ? 861 THR A O 1 ATOM 6144 C CB . THR A 1 807 ? 147.923 549.266 48.899 1.00 32.71 ? 861 THR A CB 1 ATOM 6145 O OG1 . THR A 1 807 ? 146.758 550.103 48.848 1.00 29.91 ? 861 THR A OG1 1 ATOM 6146 C CG2 . THR A 1 807 ? 149.178 550.034 48.565 1.00 29.98 ? 861 THR A CG2 1 ATOM 6147 N N . ALA A 1 808 ? 146.617 546.624 49.670 1.00 25.54 ? 862 ALA A N 1 ATOM 6148 C CA . ALA A 1 808 ? 145.554 545.953 50.393 1.00 24.77 ? 862 ALA A CA 1 ATOM 6149 C C . ALA A 1 808 ? 146.000 545.548 51.771 1.00 30.21 ? 862 ALA A C 1 ATOM 6150 O O . ALA A 1 808 ? 147.193 545.348 52.019 1.00 31.46 ? 862 ALA A O 1 ATOM 6151 C CB . ALA A 1 808 ? 145.062 544.739 49.612 1.00 24.95 ? 862 ALA A CB 1 ATOM 6152 N N . GLN A 1 809 ? 145.042 545.476 52.696 1.00 26.23 ? 863 GLN A N 1 ATOM 6153 C CA . GLN A 1 809 ? 145.293 544.968 54.025 1.00 25.03 ? 863 GLN A CA 1 ATOM 6154 C C . GLN A 1 809 ? 144.091 544.278 54.601 1.00 30.08 ? 863 GLN A C 1 ATOM 6155 O O . GLN A 1 809 ? 142.954 544.578 54.250 1.00 31.52 ? 863 GLN A O 1 ATOM 6156 C CB . GLN A 1 809 ? 145.856 546.021 54.983 1.00 26.26 ? 863 GLN A CB 1 ATOM 6157 C CG . GLN A 1 809 ? 144.897 547.133 55.361 1.00 53.56 ? 863 GLN A CG 1 ATOM 6158 C CD . GLN A 1 809 ? 145.549 548.107 56.315 1.00 87.73 ? 863 GLN A CD 1 ATOM 6159 O OE1 . GLN A 1 809 ? 146.715 547.964 56.703 1.00 86.21 ? 863 GLN A OE1 1 ATOM 6160 N NE2 . GLN A 1 809 ? 144.805 549.121 56.738 1.00 82.73 ? 863 GLN A NE2 1 ATOM 6161 N N . GLY A 1 810 ? 144.354 543.398 55.543 1.00 26.57 ? 864 GLY A N 1 ATOM 6162 C CA . GLY A 1 810 ? 143.304 542.701 56.263 1.00 25.83 ? 864 GLY A CA 1 ATOM 6163 C C . GLY A 1 810 ? 143.877 541.965 57.442 1.00 26.80 ? 864 GLY A C 1 ATOM 6164 O O . GLY A 1 810 ? 145.074 541.719 57.478 1.00 25.22 ? 864 GLY A O 1 ATOM 6165 N N . GLU A 1 811 ? 143.031 541.638 58.427 1.00 23.61 ? 865 GLU A N 1 ATOM 6166 C CA . GLU A 1 811 ? 143.444 540.883 59.598 1.00 21.68 ? 865 GLU A CA 1 ATOM 6167 C C . GLU A 1 811 ? 142.762 539.545 59.610 1.00 22.22 ? 865 GLU A C 1 ATOM 6168 O O . GLU A 1 811 ? 141.801 539.295 58.867 1.00 22.62 ? 865 GLU A O 1 ATOM 6169 C CB . GLU A 1 811 ? 143.130 541.624 60.898 1.00 23.04 ? 865 GLU A CB 1 ATOM 6170 C CG . GLU A 1 811 ? 143.784 542.986 61.051 1.00 26.79 ? 865 GLU A CG 1 ATOM 6171 C CD . GLU A 1 811 ? 143.593 543.621 62.409 1.00 44.75 ? 865 GLU A CD 1 ATOM 6172 O OE1 . GLU A 1 811 ? 142.606 543.288 63.102 1.00 44.79 ? 865 GLU A OE1 1 ATOM 6173 O OE2 . GLU A 1 811 ? 144.427 544.480 62.770 1.00 53.75 ? 865 GLU A OE2 1 ATOM 6174 N N . LEU A 1 812 ? 143.276 538.673 60.453 1.00 16.95 ? 866 LEU A N 1 ATOM 6175 C CA . LEU A 1 812 ? 142.704 537.361 60.734 1.00 15.23 ? 866 LEU A CA 1 ATOM 6176 C C . LEU A 1 812 ? 142.905 537.017 62.190 1.00 18.96 ? 866 LEU A C 1 ATOM 6177 O O . LEU A 1 812 ? 144.031 537.039 62.684 1.00 18.13 ? 866 LEU A O 1 ATOM 6178 C CB . LEU A 1 812 ? 143.328 536.290 59.850 1.00 14.44 ? 866 LEU A CB 1 ATOM 6179 C CG . LEU A 1 812 ? 142.946 534.856 60.131 1.00 17.59 ? 866 LEU A CG 1 ATOM 6180 C CD1 . LEU A 1 812 ? 141.470 534.643 59.930 1.00 17.88 ? 866 LEU A CD1 1 ATOM 6181 C CD2 . LEU A 1 812 ? 143.722 533.955 59.239 1.00 17.99 ? 866 LEU A CD2 1 ATOM 6182 N N . PHE A 1 813 ? 141.807 536.719 62.883 1.00 17.76 ? 867 PHE A N 1 ATOM 6183 C CA . PHE A 1 813 ? 141.838 536.230 64.255 1.00 17.35 ? 867 PHE A CA 1 ATOM 6184 C C . PHE A 1 813 ? 141.534 534.707 64.249 1.00 21.96 ? 867 PHE A C 1 ATOM 6185 O O . PHE A 1 813 ? 140.592 534.269 63.604 1.00 22.02 ? 867 PHE A O 1 ATOM 6186 C CB . PHE A 1 813 ? 140.813 536.968 65.108 1.00 17.80 ? 867 PHE A CB 1 ATOM 6187 C CG . PHE A 1 813 ? 140.650 536.374 66.477 1.00 18.29 ? 867 PHE A CG 1 ATOM 6188 C CD1 . PHE A 1 813 ? 141.561 536.657 67.485 1.00 20.48 ? 867 PHE A CD1 1 ATOM 6189 C CD2 . PHE A 1 813 ? 139.602 535.506 66.754 1.00 19.96 ? 867 PHE A CD2 1 ATOM 6190 C CE1 . PHE A 1 813 ? 141.438 536.073 68.734 1.00 21.88 ? 867 PHE A CE1 1 ATOM 6191 C CE2 . PHE A 1 813 ? 139.463 534.935 68.018 1.00 23.34 ? 867 PHE A CE2 1 ATOM 6192 C CZ . PHE A 1 813 ? 140.384 535.226 69.003 1.00 21.57 ? 867 PHE A CZ 1 ATOM 6193 N N . LEU A 1 814 ? 142.294 533.936 65.011 1.00 20.27 ? 868 LEU A N 1 ATOM 6194 C CA . LEU A 1 814 ? 142.115 532.491 65.170 1.00 21.00 ? 868 LEU A CA 1 ATOM 6195 C C . LEU A 1 814 ? 142.369 532.110 66.610 1.00 24.62 ? 868 LEU A C 1 ATOM 6196 O O . LEU A 1 814 ? 143.268 532.659 67.246 1.00 26.11 ? 868 LEU A O 1 ATOM 6197 C CB . LEU A 1 814 ? 143.133 531.734 64.325 1.00 21.40 ? 868 LEU A CB 1 ATOM 6198 C CG . LEU A 1 814 ? 142.972 531.847 62.827 1.00 27.16 ? 868 LEU A CG 1 ATOM 6199 C CD1 . LEU A 1 814 ? 144.164 531.254 62.152 1.00 27.50 ? 868 LEU A CD1 1 ATOM 6200 C CD2 . LEU A 1 814 ? 141.690 531.167 62.367 1.00 30.45 ? 868 LEU A CD2 1 ATOM 6201 N N . ASP A 1 815 ? 141.606 531.169 67.115 1.00 17.20 ? 869 ASP A N 1 ATOM 6202 C CA . ASP A 1 815 ? 141.822 530.603 68.420 1.00 16.89 ? 869 ASP A CA 1 ATOM 6203 C C . ASP A 1 815 ? 141.250 529.195 68.373 1.00 24.29 ? 869 ASP A C 1 ATOM 6204 O O . ASP A 1 815 ? 140.972 528.703 67.270 1.00 26.08 ? 869 ASP A O 1 ATOM 6205 C CB . ASP A 1 815 ? 141.211 531.474 69.519 1.00 17.81 ? 869 ASP A CB 1 ATOM 6206 C CG . ASP A 1 815 ? 139.719 531.399 69.605 1.00 22.50 ? 869 ASP A CG 1 ATOM 6207 O OD1 . ASP A 1 815 ? 139.086 530.986 68.609 1.00 22.04 ? 869 ASP A OD1 1 ATOM 6208 O OD2 . ASP A 1 815 ? 139.179 531.767 70.653 1.00 27.05 ? 869 ASP A OD2 1 ATOM 6209 N N . ASP A 1 816 ? 140.993 528.568 69.530 1.00 19.37 ? 870 ASP A N 1 ATOM 6210 C CA . ASP A 1 816 ? 140.467 527.207 69.526 1.00 18.98 ? 870 ASP A CA 1 ATOM 6211 C C . ASP A 1 816 ? 138.984 527.122 69.095 1.00 22.56 ? 870 ASP A C 1 ATOM 6212 O O . ASP A 1 816 ? 138.454 526.017 68.963 1.00 22.30 ? 870 ASP A O 1 ATOM 6213 C CB . ASP A 1 816 ? 140.711 526.521 70.883 1.00 21.13 ? 870 ASP A CB 1 ATOM 6214 C CG . ASP A 1 816 ? 139.983 527.135 72.069 1.00 27.22 ? 870 ASP A CG 1 ATOM 6215 O OD1 . ASP A 1 816 ? 138.986 527.879 71.849 1.00 28.97 ? 870 ASP A OD1 1 ATOM 6216 O OD2 . ASP A 1 816 ? 140.413 526.891 73.213 1.00 29.13 ? 870 ASP A OD2 1 ATOM 6217 N N . GLY A 1 817 ? 138.337 528.273 68.909 1.00 20.17 ? 871 GLY A N 1 ATOM 6218 C CA . GLY A 1 817 ? 136.954 528.365 68.461 1.00 19.62 ? 871 GLY A CA 1 ATOM 6219 C C . GLY A 1 817 ? 135.876 528.378 69.517 1.00 24.02 ? 871 GLY A C 1 ATOM 6220 O O . GLY A 1 817 ? 134.719 528.566 69.161 1.00 23.89 ? 871 GLY A O 1 ATOM 6221 N N . HIS A 1 818 ? 136.219 528.226 70.819 1.00 21.49 ? 872 HIS A N 1 ATOM 6222 C CA . HIS A 1 818 ? 135.170 528.118 71.828 1.00 20.40 ? 872 HIS A CA 1 ATOM 6223 C C . HIS A 1 818 ? 135.505 528.454 73.280 1.00 21.99 ? 872 HIS A C 1 ATOM 6224 O O . HIS A 1 818 ? 134.558 528.489 74.070 1.00 21.14 ? 872 HIS A O 1 ATOM 6225 C CB . HIS A 1 818 ? 134.596 526.681 71.790 1.00 21.78 ? 872 HIS A CB 1 ATOM 6226 C CG . HIS A 1 818 ? 135.582 525.599 72.144 1.00 25.85 ? 872 HIS A CG 1 ATOM 6227 N ND1 . HIS A 1 818 ? 135.514 524.934 73.354 1.00 28.04 ? 872 HIS A ND1 1 ATOM 6228 C CD2 . HIS A 1 818 ? 136.614 525.088 71.430 1.00 27.78 ? 872 HIS A CD2 1 ATOM 6229 C CE1 . HIS A 1 818 ? 136.501 524.050 73.346 1.00 27.83 ? 872 HIS A CE1 1 ATOM 6230 N NE2 . HIS A 1 818 ? 137.204 524.118 72.219 1.00 27.99 ? 872 HIS A NE2 1 ATOM 6231 N N . THR A 1 819 ? 136.782 528.624 73.679 1.00 17.61 ? 873 THR A N 1 ATOM 6232 C CA . THR A 1 819 ? 137.089 528.872 75.103 1.00 16.55 ? 873 THR A CA 1 ATOM 6233 C C . THR A 1 819 ? 137.567 530.293 75.344 1.00 24.22 ? 873 THR A C 1 ATOM 6234 O O . THR A 1 819 ? 137.842 531.035 74.397 1.00 23.67 ? 873 THR A O 1 ATOM 6235 C CB . THR A 1 819 ? 138.216 527.963 75.585 1.00 21.66 ? 873 THR A CB 1 ATOM 6236 O OG1 . THR A 1 819 ? 139.419 528.424 74.974 1.00 26.83 ? 873 THR A OG1 1 ATOM 6237 C CG2 . THR A 1 819 ? 137.960 526.454 75.321 1.00 8.36 ? 873 THR A CG2 1 ATOM 6238 N N . PHE A 1 820 ? 137.724 530.656 76.624 1.00 22.00 ? 874 PHE A N 1 ATOM 6239 C CA . PHE A 1 820 ? 138.303 531.936 76.980 1.00 20.86 ? 874 PHE A CA 1 ATOM 6240 C C . PHE A 1 820 ? 139.832 531.898 76.980 1.00 25.04 ? 874 PHE A C 1 ATOM 6241 O O . PHE A 1 820 ? 140.457 532.876 77.414 1.00 24.25 ? 874 PHE A O 1 ATOM 6242 C CB . PHE A 1 820 ? 137.802 532.399 78.344 1.00 21.64 ? 874 PHE A CB 1 ATOM 6243 C CG . PHE A 1 820 ? 136.375 532.868 78.303 1.00 21.07 ? 874 PHE A CG 1 ATOM 6244 C CD1 . PHE A 1 820 ? 136.052 534.121 77.791 1.00 22.25 ? 874 PHE A CD1 1 ATOM 6245 C CD2 . PHE A 1 820 ? 135.352 532.056 78.761 1.00 20.18 ? 874 PHE A CD2 1 ATOM 6246 C CE1 . PHE A 1 820 ? 134.730 534.544 77.731 1.00 22.13 ? 874 PHE A CE1 1 ATOM 6247 C CE2 . PHE A 1 820 ? 134.033 532.486 78.714 1.00 22.42 ? 874 PHE A CE2 1 ATOM 6248 C CZ . PHE A 1 820 ? 133.728 533.720 78.190 1.00 20.51 ? 874 PHE A CZ 1 ATOM 6249 N N . ASN A 1 821 ? 140.450 530.818 76.442 1.00 21.94 ? 875 ASN A N 1 ATOM 6250 C CA . ASN A 1 821 ? 141.911 530.702 76.413 1.00 20.31 ? 875 ASN A CA 1 ATOM 6251 C C . ASN A 1 821 ? 142.607 531.873 75.720 1.00 22.12 ? 875 ASN A C 1 ATOM 6252 O O . ASN A 1 821 ? 143.734 532.211 76.082 1.00 23.03 ? 875 ASN A O 1 ATOM 6253 C CB . ASN A 1 821 ? 142.358 529.372 75.838 1.00 17.69 ? 875 ASN A CB 1 ATOM 6254 C CG . ASN A 1 821 ? 141.971 528.181 76.678 1.00 30.29 ? 875 ASN A CG 1 ATOM 6255 O OD1 . ASN A 1 821 ? 141.498 528.318 77.808 1.00 31.54 ? 875 ASN A OD1 1 ATOM 6256 N ND2 . ASN A 1 821 ? 142.158 526.985 76.130 1.00 13.57 ? 875 ASN A ND2 1 ATOM 6257 N N . TYR A 1 822 ? 141.943 532.498 74.750 1.00 17.59 ? 876 TYR A N 1 ATOM 6258 C CA . TYR A 1 822 ? 142.457 533.688 74.085 1.00 16.57 ? 876 TYR A CA 1 ATOM 6259 C C . TYR A 1 822 ? 142.734 534.798 75.108 1.00 20.27 ? 876 TYR A C 1 ATOM 6260 O O . TYR A 1 822 ? 143.727 535.463 74.980 1.00 17.10 ? 876 TYR A O 1 ATOM 6261 C CB . TYR A 1 822 ? 141.512 534.149 72.934 1.00 15.31 ? 876 TYR A CB 1 ATOM 6262 C CG . TYR A 1 822 ? 140.288 534.899 73.406 1.00 14.28 ? 876 TYR A CG 1 ATOM 6263 C CD1 . TYR A 1 822 ? 139.174 534.219 73.891 1.00 15.17 ? 876 TYR A CD1 1 ATOM 6264 C CD2 . TYR A 1 822 ? 140.246 536.295 73.386 1.00 13.04 ? 876 TYR A CD2 1 ATOM 6265 C CE1 . TYR A 1 822 ? 138.051 534.903 74.346 1.00 12.75 ? 876 TYR A CE1 1 ATOM 6266 C CE2 . TYR A 1 822 ? 139.133 536.989 73.851 1.00 12.28 ? 876 TYR A CE2 1 ATOM 6267 C CZ . TYR A 1 822 ? 138.040 536.291 74.332 1.00 17.14 ? 876 TYR A CZ 1 ATOM 6268 O OH . TYR A 1 822 ? 136.940 536.981 74.769 1.00 17.24 ? 876 TYR A OH 1 ATOM 6269 N N . GLN A 1 823 ? 141.873 534.966 76.129 1.00 22.75 ? 877 GLN A N 1 ATOM 6270 C CA . GLN A 1 823 ? 142.049 536.020 77.102 1.00 23.46 ? 877 GLN A CA 1 ATOM 6271 C C . GLN A 1 823 ? 142.811 535.533 78.375 1.00 30.19 ? 877 GLN A C 1 ATOM 6272 O O . GLN A 1 823 ? 143.693 536.248 78.842 1.00 30.66 ? 877 GLN A O 1 ATOM 6273 C CB . GLN A 1 823 ? 140.704 536.740 77.392 1.00 24.63 ? 877 GLN A CB 1 ATOM 6274 C CG . GLN A 1 823 ? 139.986 536.422 78.696 1.00 34.34 ? 877 GLN A CG 1 ATOM 6275 C CD . GLN A 1 823 ? 138.687 537.185 78.900 1.00 44.25 ? 877 GLN A CD 1 ATOM 6276 O OE1 . GLN A 1 823 ? 138.052 537.689 77.968 1.00 36.15 ? 877 GLN A OE1 1 ATOM 6277 N NE2 . GLN A 1 823 ? 138.229 537.245 80.133 1.00 36.38 ? 877 GLN A NE2 1 ATOM 6278 N N . THR A 1 824 ? 142.556 534.321 78.875 1.00 28.44 ? 878 THR A N 1 ATOM 6279 C CA . THR A 1 824 ? 143.224 533.850 80.102 1.00 28.18 ? 878 THR A CA 1 ATOM 6280 C C . THR A 1 824 ? 144.655 533.342 79.886 1.00 32.83 ? 878 THR A C 1 ATOM 6281 O O . THR A 1 824 ? 145.447 533.373 80.832 1.00 30.98 ? 878 THR A O 1 ATOM 6282 C CB . THR A 1 824 ? 142.390 532.779 80.781 1.00 27.18 ? 878 THR A CB 1 ATOM 6283 O OG1 . THR A 1 824 ? 142.287 531.660 79.895 1.00 24.55 ? 878 THR A OG1 1 ATOM 6284 C CG2 . THR A 1 824 ? 141.017 533.281 81.137 1.00 22.10 ? 878 THR A CG2 1 ATOM 6285 N N . ARG A 1 825 ? 144.973 532.846 78.657 1.00 28.81 ? 879 ARG A N 1 ATOM 6286 C CA . ARG A 1 825 ? 146.275 532.257 78.337 1.00 27.83 ? 879 ARG A CA 1 ATOM 6287 C C . ARG A 1 825 ? 146.958 532.894 77.129 1.00 32.08 ? 879 ARG A C 1 ATOM 6288 O O . ARG A 1 825 ? 148.049 532.458 76.751 1.00 31.65 ? 879 ARG A O 1 ATOM 6289 C CB . ARG A 1 825 ? 146.102 530.754 78.079 1.00 26.42 ? 879 ARG A CB 1 ATOM 6290 C CG . ARG A 1 825 ? 145.673 529.901 79.263 1.00 28.26 ? 879 ARG A CG 1 ATOM 6291 C CD . ARG A 1 825 ? 145.827 528.416 78.918 1.00 36.34 ? 879 ARG A CD 1 ATOM 6292 N NE . ARG A 1 825 ? 146.088 527.611 80.116 1.00 55.56 ? 879 ARG A NE 1 ATOM 6293 C CZ . ARG A 1 825 ? 147.245 527.010 80.403 1.00 75.01 ? 879 ARG A CZ 1 ATOM 6294 N NH1 . ARG A 1 825 ? 148.268 527.082 79.560 1.00 45.98 ? 879 ARG A NH1 1 ATOM 6295 N NH2 . ARG A 1 825 ? 147.378 526.314 81.527 1.00 75.92 ? 879 ARG A NH2 1 ATOM 6296 N N . HIS A 1 826 ? 146.300 533.883 76.492 1.00 28.05 ? 880 HIS A N 1 ATOM 6297 C CA . HIS A 1 826 ? 146.790 534.537 75.290 1.00 27.40 ? 880 HIS A CA 1 ATOM 6298 C C . HIS A 1 826 ? 147.029 533.519 74.174 1.00 28.60 ? 880 HIS A C 1 ATOM 6299 O O . HIS A 1 826 ? 147.962 533.642 73.375 1.00 27.32 ? 880 HIS A O 1 ATOM 6300 C CB . HIS A 1 826 ? 148.004 535.432 75.587 1.00 28.65 ? 880 HIS A CB 1 ATOM 6301 C CG . HIS A 1 826 ? 147.671 536.667 76.376 1.00 31.86 ? 880 HIS A CG 1 ATOM 6302 N ND1 . HIS A 1 826 ? 148.659 537.476 76.886 1.00 33.21 ? 880 HIS A ND1 1 ATOM 6303 C CD2 . HIS A 1 826 ? 146.470 537.221 76.668 1.00 33.58 ? 880 HIS A CD2 1 ATOM 6304 C CE1 . HIS A 1 826 ? 148.036 538.483 77.479 1.00 32.59 ? 880 HIS A CE1 1 ATOM 6305 N NE2 . HIS A 1 826 ? 146.721 538.371 77.378 1.00 33.08 ? 880 HIS A NE2 1 ATOM 6306 N N . GLU A 1 827 ? 146.142 532.522 74.111 1.00 23.26 ? 881 GLU A N 1 ATOM 6307 C CA . GLU A 1 827 ? 146.177 531.503 73.083 1.00 21.49 ? 881 GLU A CA 1 ATOM 6308 C C . GLU A 1 827 ? 145.231 531.864 71.938 1.00 24.10 ? 881 GLU A C 1 ATOM 6309 O O . GLU A 1 827 ? 144.044 531.532 71.922 1.00 22.57 ? 881 GLU A O 1 ATOM 6310 C CB . GLU A 1 827 ? 145.930 530.120 73.651 1.00 22.70 ? 881 GLU A CB 1 ATOM 6311 C CG . GLU A 1 827 ? 147.004 529.681 74.625 1.00 26.51 ? 881 GLU A CG 1 ATOM 6312 C CD . GLU A 1 827 ? 146.664 528.437 75.408 1.00 41.16 ? 881 GLU A CD 1 ATOM 6313 O OE1 . GLU A 1 827 ? 147.532 527.972 76.178 1.00 44.74 ? 881 GLU A OE1 1 ATOM 6314 O OE2 . GLU A 1 827 ? 145.505 527.975 75.326 1.00 40.89 ? 881 GLU A OE2 1 ATOM 6315 N N . PHE A 1 828 ? 145.798 532.583 70.984 1.00 22.14 ? 882 PHE A N 1 ATOM 6316 C CA . PHE A 1 828 ? 145.152 533.045 69.766 1.00 22.09 ? 882 PHE A CA 1 ATOM 6317 C C . PHE A 1 828 ? 146.208 533.603 68.841 1.00 25.64 ? 882 PHE A C 1 ATOM 6318 O O . PHE A 1 828 ? 147.350 533.813 69.245 1.00 26.86 ? 882 PHE A O 1 ATOM 6319 C CB . PHE A 1 828 ? 144.134 534.189 70.078 1.00 24.05 ? 882 PHE A CB 1 ATOM 6320 C CG . PHE A 1 828 ? 144.770 535.499 70.516 1.00 24.67 ? 882 PHE A CG 1 ATOM 6321 C CD1 . PHE A 1 828 ? 145.183 535.689 71.843 1.00 26.01 ? 882 PHE A CD1 1 ATOM 6322 C CD2 . PHE A 1 828 ? 144.972 536.532 69.602 1.00 25.90 ? 882 PHE A CD2 1 ATOM 6323 C CE1 . PHE A 1 828 ? 145.782 536.893 72.244 1.00 26.51 ? 882 PHE A CE1 1 ATOM 6324 C CE2 . PHE A 1 828 ? 145.581 537.738 70.003 1.00 27.59 ? 882 PHE A CE2 1 ATOM 6325 C CZ . PHE A 1 828 ? 145.957 537.918 71.327 1.00 25.33 ? 882 PHE A CZ 1 ATOM 6326 N N . LEU A 1 829 ? 145.791 533.884 67.614 1.00 21.24 ? 883 LEU A N 1 ATOM 6327 C CA . LEU A 1 829 ? 146.572 534.561 66.600 1.00 20.86 ? 883 LEU A CA 1 ATOM 6328 C C . LEU A 1 829 ? 145.796 535.754 66.066 1.00 25.65 ? 883 LEU A C 1 ATOM 6329 O O . LEU A 1 829 ? 144.595 535.662 65.782 1.00 25.38 ? 883 LEU A O 1 ATOM 6330 C CB . LEU A 1 829 ? 146.950 533.652 65.405 1.00 19.86 ? 883 LEU A CB 1 ATOM 6331 C CG . LEU A 1 829 ? 147.861 532.459 65.695 1.00 22.65 ? 883 LEU A CG 1 ATOM 6332 C CD1 . LEU A 1 829 ? 147.952 531.574 64.483 1.00 22.07 ? 883 LEU A CD1 1 ATOM 6333 C CD2 . LEU A 1 829 ? 149.263 532.908 66.131 1.00 20.53 ? 883 LEU A CD2 1 ATOM 6334 N N . LEU A 1 830 ? 146.489 536.874 65.921 1.00 21.20 ? 884 LEU A N 1 ATOM 6335 C CA . LEU A 1 830 ? 145.933 538.020 65.236 1.00 19.45 ? 884 LEU A CA 1 ATOM 6336 C C . LEU A 1 830 ? 146.967 538.372 64.203 1.00 24.97 ? 884 LEU A C 1 ATOM 6337 O O . LEU A 1 830 ? 148.040 538.882 64.527 1.00 22.03 ? 884 LEU A O 1 ATOM 6338 C CB . LEU A 1 830 ? 145.536 539.202 66.127 1.00 18.34 ? 884 LEU A CB 1 ATOM 6339 C CG . LEU A 1 830 ? 144.773 540.327 65.406 1.00 21.97 ? 884 LEU A CG 1 ATOM 6340 C CD1 . LEU A 1 830 ? 143.355 539.896 64.973 1.00 20.64 ? 884 LEU A CD1 1 ATOM 6341 C CD2 . LEU A 1 830 ? 144.747 541.592 66.218 1.00 20.69 ? 884 LEU A CD2 1 ATOM 6342 N N . ARG A 1 831 ? 146.680 537.993 62.959 1.00 25.51 ? 885 ARG A N 1 ATOM 6343 C CA . ARG A 1 831 ? 147.590 538.244 61.858 1.00 25.97 ? 885 ARG A CA 1 ATOM 6344 C C . ARG A 1 831 ? 147.198 539.459 61.084 1.00 31.57 ? 885 ARG A C 1 ATOM 6345 O O . ARG A 1 831 ? 146.010 539.726 60.928 1.00 32.70 ? 885 ARG A O 1 ATOM 6346 C CB . ARG A 1 831 ? 147.627 537.029 60.899 1.00 25.84 ? 885 ARG A CB 1 ATOM 6347 C CG . ARG A 1 831 ? 148.069 535.697 61.531 1.00 26.94 ? 885 ARG A CG 1 ATOM 6348 C CD . ARG A 1 831 ? 149.363 535.814 62.307 1.00 21.09 ? 885 ARG A CD 1 ATOM 6349 N NE . ARG A 1 831 ? 150.446 536.143 61.396 1.00 22.80 ? 885 ARG A NE 1 ATOM 6350 C CZ . ARG A 1 831 ? 151.698 536.322 61.771 1.00 33.14 ? 885 ARG A CZ 1 ATOM 6351 N NH1 . ARG A 1 831 ? 152.030 536.235 63.053 1.00 6.29 ? 885 ARG A NH1 1 ATOM 6352 N NH2 . ARG A 1 831 ? 152.631 536.598 60.871 1.00 19.72 ? 885 ARG A NH2 1 ATOM 6353 N N . ARG A 1 832 ? 148.198 540.185 60.566 1.00 30.06 ? 886 ARG A N 1 ATOM 6354 C CA . ARG A 1 832 ? 147.990 541.266 59.600 1.00 30.21 ? 886 ARG A CA 1 ATOM 6355 C C . ARG A 1 832 ? 148.558 540.800 58.254 1.00 30.71 ? 886 ARG A C 1 ATOM 6356 O O . ARG A 1 832 ? 149.720 540.405 58.171 1.00 31.27 ? 886 ARG A O 1 ATOM 6357 C CB . ARG A 1 832 ? 148.615 542.631 60.011 1.00 31.92 ? 886 ARG A CB 1 ATOM 6358 C CG . ARG A 1 832 ? 148.319 543.764 58.992 1.00 44.95 ? 886 ARG A CG 1 ATOM 6359 C CD . ARG A 1 832 ? 148.617 545.180 59.479 1.00 66.08 ? 886 ARG A CD 1 ATOM 6360 N NE . ARG A 1 832 ? 149.918 545.680 59.008 1.00 89.15 ? 886 ARG A NE 1 ATOM 6361 C CZ . ARG A 1 832 ? 150.113 546.444 57.928 1.00 110.04 ? 886 ARG A CZ 1 ATOM 6362 N NH1 . ARG A 1 832 ? 149.090 546.801 57.162 1.00 100.97 ? 886 ARG A NH1 1 ATOM 6363 N NH2 . ARG A 1 832 ? 151.337 546.845 57.603 1.00 94.11 ? 886 ARG A NH2 1 ATOM 6364 N N . PHE A 1 833 ? 147.742 540.879 57.204 1.00 24.17 ? 887 PHE A N 1 ATOM 6365 C CA . PHE A 1 833 ? 148.160 540.621 55.832 1.00 22.26 ? 887 PHE A CA 1 ATOM 6366 C C . PHE A 1 833 ? 148.164 541.978 55.155 1.00 27.18 ? 887 PHE A C 1 ATOM 6367 O O . PHE A 1 833 ? 147.205 542.728 55.292 1.00 26.15 ? 887 PHE A O 1 ATOM 6368 C CB . PHE A 1 833 ? 147.220 539.651 55.111 1.00 22.76 ? 887 PHE A CB 1 ATOM 6369 C CG . PHE A 1 833 ? 147.093 538.342 55.830 1.00 22.68 ? 887 PHE A CG 1 ATOM 6370 C CD1 . PHE A 1 833 ? 148.178 537.492 55.944 1.00 23.80 ? 887 PHE A CD1 1 ATOM 6371 C CD2 . PHE A 1 833 ? 145.905 537.985 56.457 1.00 24.41 ? 887 PHE A CD2 1 ATOM 6372 C CE1 . PHE A 1 833 ? 148.082 536.304 56.655 1.00 24.05 ? 887 PHE A CE1 1 ATOM 6373 C CE2 . PHE A 1 833 ? 145.799 536.764 57.141 1.00 26.02 ? 887 PHE A CE2 1 ATOM 6374 C CZ . PHE A 1 833 ? 146.893 535.942 57.244 1.00 22.92 ? 887 PHE A CZ 1 ATOM 6375 N N . SER A 1 834 ? 149.266 542.322 54.498 1.00 24.27 ? 888 SER A N 1 ATOM 6376 C CA . SER A 1 834 ? 149.391 543.589 53.815 1.00 24.53 ? 888 SER A CA 1 ATOM 6377 C C . SER A 1 834 ? 150.061 543.378 52.483 1.00 27.85 ? 888 SER A C 1 ATOM 6378 O O . SER A 1 834 ? 150.977 542.562 52.339 1.00 28.14 ? 888 SER A O 1 ATOM 6379 C CB . SER A 1 834 ? 150.126 544.622 54.669 1.00 29.29 ? 888 SER A CB 1 ATOM 6380 O OG . SER A 1 834 ? 151.414 544.182 55.065 1.00 37.00 ? 888 SER A OG 1 ATOM 6381 N N . PHE A 1 835 ? 149.540 544.058 51.498 1.00 22.71 ? 889 PHE A N 1 ATOM 6382 C CA . PHE A 1 835 ? 150.081 544.015 50.168 1.00 22.18 ? 889 PHE A CA 1 ATOM 6383 C C . PHE A 1 835 ? 150.425 545.431 49.740 1.00 28.91 ? 889 PHE A C 1 ATOM 6384 O O . PHE A 1 835 ? 149.588 546.338 49.863 1.00 27.40 ? 889 PHE A O 1 ATOM 6385 C CB . PHE A 1 835 ? 149.053 543.435 49.182 1.00 22.71 ? 889 PHE A CB 1 ATOM 6386 C CG . PHE A 1 835 ? 149.661 543.130 47.842 1.00 22.86 ? 889 PHE A CG 1 ATOM 6387 C CD1 . PHE A 1 835 ? 149.895 544.144 46.915 1.00 23.89 ? 889 PHE A CD1 1 ATOM 6388 C CD2 . PHE A 1 835 ? 150.028 541.832 47.511 1.00 24.58 ? 889 PHE A CD2 1 ATOM 6389 C CE1 . PHE A 1 835 ? 150.509 543.864 45.691 1.00 25.03 ? 889 PHE A CE1 1 ATOM 6390 C CE2 . PHE A 1 835 ? 150.632 541.548 46.283 1.00 26.95 ? 889 PHE A CE2 1 ATOM 6391 C CZ . PHE A 1 835 ? 150.861 542.565 45.377 1.00 25.22 ? 889 PHE A CZ 1 ATOM 6392 N N . SER A 1 836 ? 151.640 545.614 49.193 1.00 26.70 ? 890 SER A N 1 ATOM 6393 C CA . SER A 1 836 ? 152.037 546.847 48.529 1.00 27.91 ? 890 SER A CA 1 ATOM 6394 C C . SER A 1 836 ? 153.241 546.604 47.650 1.00 35.64 ? 890 SER A C 1 ATOM 6395 O O . SER A 1 836 ? 154.033 545.669 47.907 1.00 35.49 ? 890 SER A O 1 ATOM 6396 C CB . SER A 1 836 ? 152.194 548.041 49.472 1.00 33.20 ? 890 SER A CB 1 ATOM 6397 O OG . SER A 1 836 ? 153.532 548.266 49.869 1.00 50.82 ? 890 SER A OG 1 ATOM 6398 N N . GLY A 1 837 ? 153.306 547.388 46.570 1.00 33.47 ? 891 GLY A N 1 ATOM 6399 C CA . GLY A 1 837 ? 154.354 547.269 45.571 1.00 34.26 ? 891 GLY A CA 1 ATOM 6400 C C . GLY A 1 837 ? 154.135 545.954 44.871 1.00 41.10 ? 891 GLY A C 1 ATOM 6401 O O . GLY A 1 837 ? 153.140 545.801 44.151 1.00 44.08 ? 891 GLY A O 1 ATOM 6402 N N . SER A 1 838 ? 154.988 544.964 45.146 1.00 34.49 ? 892 SER A N 1 ATOM 6403 C CA . SER A 1 838 ? 154.769 543.675 44.535 1.00 32.48 ? 892 SER A CA 1 ATOM 6404 C C . SER A 1 838 ? 154.891 542.540 45.568 1.00 32.40 ? 892 SER A C 1 ATOM 6405 O O . SER A 1 838 ? 155.147 541.392 45.208 1.00 30.90 ? 892 SER A O 1 ATOM 6406 C CB . SER A 1 838 ? 155.726 543.521 43.364 1.00 37.93 ? 892 SER A CB 1 ATOM 6407 O OG . SER A 1 838 ? 157.064 543.707 43.802 1.00 50.15 ? 892 SER A OG 1 ATOM 6408 N N . THR A 1 839 ? 154.606 542.858 46.845 1.00 27.54 ? 893 THR A N 1 ATOM 6409 C CA . THR A 1 839 ? 154.797 541.966 47.977 1.00 25.77 ? 893 THR A CA 1 ATOM 6410 C C . THR A 1 839 ? 153.585 541.840 48.890 1.00 27.56 ? 893 THR A C 1 ATOM 6411 O O . THR A 1 839 ? 153.005 542.845 49.319 1.00 26.41 ? 893 THR A O 1 ATOM 6412 C CB . THR A 1 839 ? 155.998 542.459 48.819 1.00 30.00 ? 893 THR A CB 1 ATOM 6413 O OG1 . THR A 1 839 ? 157.096 542.758 47.964 1.00 39.90 ? 893 THR A OG1 1 ATOM 6414 C CG2 . THR A 1 839 ? 156.456 541.438 49.833 1.00 24.51 ? 893 THR A CG2 1 ATOM 6415 N N . LEU A 1 840 ? 153.246 540.590 49.220 1.00 21.31 ? 894 LEU A N 1 ATOM 6416 C CA . LEU A 1 840 ? 152.219 540.276 50.199 1.00 20.01 ? 894 LEU A CA 1 ATOM 6417 C C . LEU A 1 840 ? 152.969 539.821 51.476 1.00 24.86 ? 894 LEU A C 1 ATOM 6418 O O . LEU A 1 840 ? 153.827 538.948 51.400 1.00 24.67 ? 894 LEU A O 1 ATOM 6419 C CB . LEU A 1 840 ? 151.318 539.157 49.677 1.00 19.69 ? 894 LEU A CB 1 ATOM 6420 C CG . LEU A 1 840 ? 150.304 538.619 50.635 1.00 23.60 ? 894 LEU A CG 1 ATOM 6421 C CD1 . LEU A 1 840 ? 149.378 539.737 51.147 1.00 22.89 ? 894 LEU A CD1 1 ATOM 6422 C CD2 . LEU A 1 840 ? 149.509 537.544 49.959 1.00 25.32 ? 894 LEU A CD2 1 ATOM 6423 N N . VAL A 1 841 ? 152.671 540.416 52.621 1.00 20.33 ? 895 VAL A N 1 ATOM 6424 C CA . VAL A 1 841 ? 153.362 540.105 53.857 1.00 20.45 ? 895 VAL A CA 1 ATOM 6425 C C . VAL A 1 841 ? 152.385 539.703 54.946 1.00 28.22 ? 895 VAL A C 1 ATOM 6426 O O . VAL A 1 841 ? 151.359 540.382 55.138 1.00 28.62 ? 895 VAL A O 1 ATOM 6427 C CB . VAL A 1 841 ? 154.198 541.345 54.328 1.00 22.98 ? 895 VAL A CB 1 ATOM 6428 C CG1 . VAL A 1 841 ? 154.836 541.122 55.693 1.00 21.09 ? 895 VAL A CG1 1 ATOM 6429 C CG2 . VAL A 1 841 ? 155.266 541.709 53.293 1.00 23.10 ? 895 VAL A CG2 1 ATOM 6430 N N . SER A 1 842 ? 152.740 538.643 55.709 1.00 24.39 ? 896 SER A N 1 ATOM 6431 C CA . SER A 1 842 ? 152.005 538.285 56.926 1.00 24.05 ? 896 SER A CA 1 ATOM 6432 C C . SER A 1 842 ? 152.893 538.661 58.092 1.00 30.31 ? 896 SER A C 1 ATOM 6433 O O . SER A 1 842 ? 154.055 538.232 58.163 1.00 30.89 ? 896 SER A O 1 ATOM 6434 C CB . SER A 1 842 ? 151.688 536.795 57.012 1.00 24.41 ? 896 SER A CB 1 ATOM 6435 O OG . SER A 1 842 ? 151.234 536.493 58.319 1.00 24.62 ? 896 SER A OG 1 ATOM 6436 N N . SER A 1 843 ? 152.352 539.461 59.004 1.00 26.75 ? 897 SER A N 1 ATOM 6437 C CA . SER A 1 843 ? 153.050 539.862 60.229 1.00 25.06 ? 897 SER A CA 1 ATOM 6438 C C . SER A 1 843 ? 152.075 539.730 61.399 1.00 28.68 ? 897 SER A C 1 ATOM 6439 O O . SER A 1 843 ? 150.863 539.622 61.189 1.00 26.36 ? 897 SER A O 1 ATOM 6440 C CB . SER A 1 843 ? 153.572 541.292 60.108 1.00 25.35 ? 897 SER A CB 1 ATOM 6441 O OG . SER A 1 843 ? 152.533 542.224 59.866 1.00 29.54 ? 897 SER A OG 1 ATOM 6442 N N . SER A 1 844 ? 152.593 539.699 62.629 1.00 26.64 ? 898 SER A N 1 ATOM 6443 C CA . SER A 1 844 ? 151.728 539.647 63.803 1.00 26.14 ? 898 SER A CA 1 ATOM 6444 C C . SER A 1 844 ? 151.083 541.021 64.064 1.00 29.42 ? 898 SER A C 1 ATOM 6445 O O . SER A 1 844 ? 151.805 542.018 64.082 1.00 30.02 ? 898 SER A O 1 ATOM 6446 C CB . SER A 1 844 ? 152.530 539.236 65.032 1.00 29.77 ? 898 SER A CB 1 ATOM 6447 O OG . SER A 1 844 ? 151.670 539.151 66.153 1.00 33.84 ? 898 SER A OG 1 ATOM 6448 N N . ALA A 1 845 ? 149.749 541.071 64.310 1.00 24.52 ? 899 ALA A N 1 ATOM 6449 C CA . ALA A 1 845 ? 149.051 542.311 64.682 1.00 23.45 ? 899 ALA A CA 1 ATOM 6450 C C . ALA A 1 845 ? 148.882 542.397 66.191 1.00 28.99 ? 899 ALA A C 1 ATOM 6451 O O . ALA A 1 845 ? 148.378 543.392 66.706 1.00 30.19 ? 899 ALA A O 1 ATOM 6452 C CB . ALA A 1 845 ? 147.705 542.418 63.983 1.00 23.85 ? 899 ALA A CB 1 ATOM 6453 N N . ASP A 1 846 ? 149.277 541.348 66.899 1.00 25.64 ? 900 ASP A N 1 ATOM 6454 C CA . ASP A 1 846 ? 149.282 541.299 68.351 1.00 25.81 ? 900 ASP A CA 1 ATOM 6455 C C . ASP A 1 846 ? 150.268 540.215 68.769 1.00 29.37 ? 900 ASP A C 1 ATOM 6456 O O . ASP A 1 846 ? 149.894 539.030 68.871 1.00 27.88 ? 900 ASP A O 1 ATOM 6457 C CB . ASP A 1 846 ? 147.903 541.078 68.968 1.00 27.79 ? 900 ASP A CB 1 ATOM 6458 C CG . ASP A 1 846 ? 147.916 541.241 70.476 1.00 34.99 ? 900 ASP A CG 1 ATOM 6459 O OD1 . ASP A 1 846 ? 149.019 541.342 71.061 1.00 38.33 ? 900 ASP A OD1 1 ATOM 6460 O OD2 . ASP A 1 846 ? 146.837 541.253 71.073 1.00 37.60 ? 900 ASP A OD2 1 ATOM 6461 N N . PRO A 1 847 ? 151.534 540.620 69.044 1.00 24.57 ? 901 PRO A N 1 ATOM 6462 C CA . PRO A 1 847 ? 152.550 539.611 69.385 1.00 24.21 ? 901 PRO A CA 1 ATOM 6463 C C . PRO A 1 847 ? 152.289 538.853 70.690 1.00 28.38 ? 901 PRO A C 1 ATOM 6464 O O . PRO A 1 847 ? 152.929 537.833 70.906 1.00 27.21 ? 901 PRO A O 1 ATOM 6465 C CB . PRO A 1 847 ? 153.862 540.406 69.394 1.00 25.89 ? 901 PRO A CB 1 ATOM 6466 C CG . PRO A 1 847 ? 153.550 541.726 68.685 1.00 29.23 ? 901 PRO A CG 1 ATOM 6467 C CD . PRO A 1 847 ? 152.115 541.984 68.984 1.00 24.27 ? 901 PRO A CD 1 ATOM 6468 N N . LYS A 1 848 ? 151.316 539.291 71.525 1.00 26.31 ? 902 LYS A N 1 ATOM 6469 C CA . LYS A 1 848 ? 150.983 538.581 72.765 1.00 26.15 ? 902 LYS A CA 1 ATOM 6470 C C . LYS A 1 848 ? 150.307 537.235 72.482 1.00 29.87 ? 902 LYS A C 1 ATOM 6471 O O . LYS A 1 848 ? 150.389 536.346 73.319 1.00 30.30 ? 902 LYS A O 1 ATOM 6472 C CB . LYS A 1 848 ? 150.074 539.429 73.652 1.00 28.98 ? 902 LYS A CB 1 ATOM 6473 C CG . LYS A 1 848 ? 150.705 540.723 74.145 1.00 47.99 ? 902 LYS A CG 1 ATOM 6474 C CD . LYS A 1 848 ? 149.971 541.290 75.379 1.00 68.72 ? 902 LYS A CD 1 ATOM 6475 C CE . LYS A 1 848 ? 148.553 541.797 75.128 1.00 82.85 ? 902 LYS A CE 1 ATOM 6476 N NZ . LYS A 1 848 ? 148.531 543.088 74.378 1.00 90.79 ? 902 LYS A NZ 1 ATOM 6477 N N . GLY A 1 849 ? 149.663 537.104 71.319 1.00 25.10 ? 903 GLY A N 1 ATOM 6478 C CA . GLY A 1 849 ? 148.933 535.912 70.934 1.00 23.55 ? 903 GLY A CA 1 ATOM 6479 C C . GLY A 1 849 ? 149.769 534.853 70.278 1.00 28.47 ? 903 GLY A C 1 ATOM 6480 O O . GLY A 1 849 ? 150.327 535.085 69.216 1.00 28.57 ? 903 GLY A O 1 ATOM 6481 N N . HIS A 1 850 ? 149.816 533.670 70.885 1.00 26.71 ? 904 HIS A N 1 ATOM 6482 C CA . HIS A 1 850 ? 150.516 532.492 70.349 1.00 26.52 ? 904 HIS A CA 1 ATOM 6483 C C . HIS A 1 850 ? 149.528 531.359 70.276 1.00 26.01 ? 904 HIS A C 1 ATOM 6484 O O . HIS A 1 850 ? 148.694 531.218 71.164 1.00 24.14 ? 904 HIS A O 1 ATOM 6485 C CB . HIS A 1 850 ? 151.731 532.094 71.215 1.00 27.84 ? 904 HIS A CB 1 ATOM 6486 C CG . HIS A 1 850 ? 152.799 533.152 71.272 1.00 32.33 ? 904 HIS A CG 1 ATOM 6487 N ND1 . HIS A 1 850 ? 152.789 534.140 72.259 1.00 34.68 ? 904 HIS A ND1 1 ATOM 6488 C CD2 . HIS A 1 850 ? 153.859 533.377 70.445 1.00 34.09 ? 904 HIS A CD2 1 ATOM 6489 C CE1 . HIS A 1 850 ? 153.836 534.922 72.006 1.00 33.65 ? 904 HIS A CE1 1 ATOM 6490 N NE2 . HIS A 1 850 ? 154.515 534.503 70.930 1.00 33.88 ? 904 HIS A NE2 1 ATOM 6491 N N . LEU A 1 851 ? 149.605 530.552 69.219 1.00 21.29 ? 905 LEU A N 1 ATOM 6492 C CA . LEU A 1 851 ? 148.656 529.449 69.079 1.00 20.78 ? 905 LEU A CA 1 ATOM 6493 C C . LEU A 1 851 ? 149.258 528.267 68.365 1.00 24.70 ? 905 LEU A C 1 ATOM 6494 O O . LEU A 1 851 ? 149.771 528.426 67.261 1.00 22.83 ? 905 LEU A O 1 ATOM 6495 C CB . LEU A 1 851 ? 147.372 529.926 68.333 1.00 19.56 ? 905 LEU A CB 1 ATOM 6496 C CG . LEU A 1 851 ? 146.237 528.913 68.175 1.00 20.39 ? 905 LEU A CG 1 ATOM 6497 C CD1 . LEU A 1 851 ? 145.493 528.749 69.466 1.00 20.60 ? 905 LEU A CD1 1 ATOM 6498 C CD2 . LEU A 1 851 ? 145.289 529.317 67.071 1.00 18.88 ? 905 LEU A CD2 1 ATOM 6499 N N . GLU A 1 852 ? 149.110 527.074 68.950 1.00 24.34 ? 906 GLU A N 1 ATOM 6500 C CA . GLU A 1 852 ? 149.550 525.838 68.297 1.00 25.91 ? 906 GLU A CA 1 ATOM 6501 C C . GLU A 1 852 ? 148.426 525.449 67.393 1.00 29.67 ? 906 GLU A C 1 ATOM 6502 O O . GLU A 1 852 ? 147.335 525.150 67.869 1.00 28.46 ? 906 GLU A O 1 ATOM 6503 C CB . GLU A 1 852 ? 149.830 524.722 69.323 1.00 28.02 ? 906 GLU A CB 1 ATOM 6504 C CG . GLU A 1 852 ? 150.469 523.472 68.734 1.00 43.41 ? 906 GLU A CG 1 ATOM 6505 C CD . GLU A 1 852 ? 150.972 522.473 69.766 1.00 70.04 ? 906 GLU A CD 1 ATOM 6506 O OE1 . GLU A 1 852 ? 151.428 522.913 70.848 1.00 72.86 ? 906 GLU A OE1 1 ATOM 6507 O OE2 . GLU A 1 852 ? 150.916 521.249 69.491 1.00 49.35 ? 906 GLU A OE2 1 ATOM 6508 N N . THR A 1 853 ? 148.658 525.516 66.080 1.00 27.46 ? 907 THR A N 1 ATOM 6509 C CA . THR A 1 853 ? 147.611 525.204 65.122 1.00 25.72 ? 907 THR A CA 1 ATOM 6510 C C . THR A 1 853 ? 148.184 524.592 63.855 1.00 28.05 ? 907 THR A C 1 ATOM 6511 O O . THR A 1 853 ? 149.225 525.052 63.365 1.00 28.57 ? 907 THR A O 1 ATOM 6512 C CB . THR A 1 853 ? 146.791 526.481 64.772 1.00 24.92 ? 907 THR A CB 1 ATOM 6513 O OG1 . THR A 1 853 ? 145.817 526.134 63.779 1.00 23.88 ? 907 THR A OG1 1 ATOM 6514 C CG2 . THR A 1 853 ? 147.677 527.629 64.239 1.00 17.24 ? 907 THR A CG2 1 ATOM 6515 N N . PRO A 1 854 ? 147.433 523.647 63.251 1.00 21.73 ? 908 PRO A N 1 ATOM 6516 C CA . PRO A 1 854 ? 147.843 523.113 61.951 1.00 20.43 ? 908 PRO A CA 1 ATOM 6517 C C . PRO A 1 854 ? 147.411 524.004 60.777 1.00 24.92 ? 908 PRO A C 1 ATOM 6518 O O . PRO A 1 854 ? 147.720 523.677 59.628 1.00 25.84 ? 908 PRO A O 1 ATOM 6519 C CB . PRO A 1 854 ? 147.130 521.766 61.900 1.00 21.92 ? 908 PRO A CB 1 ATOM 6520 C CG . PRO A 1 854 ? 145.915 521.951 62.760 1.00 26.06 ? 908 PRO A CG 1 ATOM 6521 C CD . PRO A 1 854 ? 146.205 522.986 63.759 1.00 22.09 ? 908 PRO A CD 1 ATOM 6522 N N . ILE A 1 855 ? 146.700 525.118 61.036 1.00 22.07 ? 909 ILE A N 1 ATOM 6523 C CA . ILE A 1 855 ? 146.243 526.025 59.957 1.00 21.49 ? 909 ILE A CA 1 ATOM 6524 C C . ILE A 1 855 ? 147.398 526.592 59.128 1.00 23.20 ? 909 ILE A C 1 ATOM 6525 O O . ILE A 1 855 ? 148.331 527.168 59.654 1.00 23.20 ? 909 ILE A O 1 ATOM 6526 C CB . ILE A 1 855 ? 145.292 527.149 60.440 1.00 24.31 ? 909 ILE A CB 1 ATOM 6527 C CG1 . ILE A 1 855 ? 143.982 526.578 60.996 1.00 23.60 ? 909 ILE A CG1 1 ATOM 6528 C CG2 . ILE A 1 855 ? 144.963 528.096 59.289 1.00 26.07 ? 909 ILE A CG2 1 ATOM 6529 C CD1 . ILE A 1 855 ? 143.128 527.596 61.802 1.00 23.74 ? 909 ILE A CD1 1 ATOM 6530 N N . TRP A 1 856 ? 147.292 526.429 57.821 1.00 20.06 ? 910 TRP A N 1 ATOM 6531 C CA . TRP A 1 856 ? 148.246 526.893 56.822 1.00 18.69 ? 910 TRP A CA 1 ATOM 6532 C C . TRP A 1 856 ? 147.586 527.656 55.695 1.00 19.13 ? 910 TRP A C 1 ATOM 6533 O O . TRP A 1 856 ? 146.381 527.593 55.523 1.00 20.04 ? 910 TRP A O 1 ATOM 6534 C CB . TRP A 1 856 ? 149.108 525.717 56.285 1.00 17.91 ? 910 TRP A CB 1 ATOM 6535 C CG . TRP A 1 856 ? 148.343 524.575 55.660 1.00 18.79 ? 910 TRP A CG 1 ATOM 6536 C CD1 . TRP A 1 856 ? 147.645 523.601 56.312 1.00 21.53 ? 910 TRP A CD1 1 ATOM 6537 C CD2 . TRP A 1 856 ? 148.295 524.235 54.268 1.00 18.49 ? 910 TRP A CD2 1 ATOM 6538 N NE1 . TRP A 1 856 ? 147.135 522.695 55.409 1.00 20.83 ? 910 TRP A NE1 1 ATOM 6539 C CE2 . TRP A 1 856 ? 147.520 523.061 54.148 1.00 22.40 ? 910 TRP A CE2 1 ATOM 6540 C CE3 . TRP A 1 856 ? 148.807 524.827 53.101 1.00 19.51 ? 910 TRP A CE3 1 ATOM 6541 C CZ2 . TRP A 1 856 ? 147.235 522.478 52.912 1.00 21.72 ? 910 TRP A CZ2 1 ATOM 6542 C CZ3 . TRP A 1 856 ? 148.584 524.208 51.883 1.00 20.58 ? 910 TRP A CZ3 1 ATOM 6543 C CH2 . TRP A 1 856 ? 147.787 523.062 51.790 1.00 21.29 ? 910 TRP A CH2 1 ATOM 6544 N N . ILE A 1 857 ? 148.373 528.394 54.928 1.00 15.12 ? 911 ILE A N 1 ATOM 6545 C CA . ILE A 1 857 ? 147.870 529.148 53.778 1.00 14.97 ? 911 ILE A CA 1 ATOM 6546 C C . ILE A 1 857 ? 147.954 528.265 52.554 1.00 24.58 ? 911 ILE A C 1 ATOM 6547 O O . ILE A 1 857 ? 149.058 528.009 52.054 1.00 24.90 ? 911 ILE A O 1 ATOM 6548 C CB . ILE A 1 857 ? 148.634 530.464 53.568 1.00 15.79 ? 911 ILE A CB 1 ATOM 6549 C CG1 . ILE A 1 857 ? 148.771 531.275 54.883 1.00 14.71 ? 911 ILE A CG1 1 ATOM 6550 C CG2 . ILE A 1 857 ? 148.039 531.269 52.438 1.00 12.83 ? 911 ILE A CG2 1 ATOM 6551 C CD1 . ILE A 1 857 ? 147.458 531.678 55.593 1.00 25.18 ? 911 ILE A CD1 1 ATOM 6552 N N . GLU A 1 858 ? 146.793 527.841 52.023 1.00 22.40 ? 912 GLU A N 1 ATOM 6553 C CA . GLU A 1 858 ? 146.804 526.966 50.858 1.00 21.55 ? 912 GLU A CA 1 ATOM 6554 C C . GLU A 1 858 ? 146.738 527.670 49.547 1.00 26.73 ? 912 GLU A C 1 ATOM 6555 O O . GLU A 1 858 ? 147.055 527.059 48.517 1.00 28.49 ? 912 GLU A O 1 ATOM 6556 C CB . GLU A 1 858 ? 145.710 525.894 50.923 1.00 22.39 ? 912 GLU A CB 1 ATOM 6557 C CG . GLU A 1 858 ? 144.262 526.334 50.843 1.00 20.74 ? 912 GLU A CG 1 ATOM 6558 C CD . GLU A 1 858 ? 143.335 525.195 50.496 1.00 30.38 ? 912 GLU A CD 1 ATOM 6559 O OE1 . GLU A 1 858 ? 143.696 524.363 49.632 1.00 21.11 ? 912 GLU A OE1 1 ATOM 6560 O OE2 . GLU A 1 858 ? 142.207 525.182 51.032 1.00 32.91 ? 912 GLU A OE2 1 ATOM 6561 N N . ARG A 1 859 ? 146.287 528.921 49.552 1.00 21.85 ? 913 ARG A N 1 ATOM 6562 C CA . ARG A 1 859 ? 146.062 529.630 48.306 1.00 21.46 ? 913 ARG A CA 1 ATOM 6563 C C . ARG A 1 859 ? 145.962 531.113 48.544 1.00 25.17 ? 913 ARG A C 1 ATOM 6564 O O . ARG A 1 859 ? 145.523 531.546 49.618 1.00 22.62 ? 913 ARG A O 1 ATOM 6565 C CB . ARG A 1 859 ? 144.736 529.112 47.695 1.00 18.50 ? 913 ARG A CB 1 ATOM 6566 C CG . ARG A 1 859 ? 144.438 529.537 46.267 1.00 22.28 ? 913 ARG A CG 1 ATOM 6567 C CD . ARG A 1 859 ? 143.098 528.999 45.819 1.00 19.81 ? 913 ARG A CD 1 ATOM 6568 N NE . ARG A 1 859 ? 143.039 527.532 45.702 1.00 12.75 ? 913 ARG A NE 1 ATOM 6569 C CZ . ARG A 1 859 ? 142.403 526.713 46.539 1.00 25.91 ? 913 ARG A CZ 1 ATOM 6570 N NH1 . ARG A 1 859 ? 141.774 527.192 47.606 1.00 11.82 ? 913 ARG A NH1 1 ATOM 6571 N NH2 . ARG A 1 859 ? 142.379 525.414 46.308 1.00 20.75 ? 913 ARG A NH2 1 ATOM 6572 N N . VAL A 1 860 ? 146.325 531.891 47.497 1.00 23.65 ? 914 VAL A N 1 ATOM 6573 C CA . VAL A 1 860 ? 146.175 533.355 47.473 1.00 23.33 ? 914 VAL A CA 1 ATOM 6574 C C . VAL A 1 860 ? 145.535 533.703 46.154 1.00 27.80 ? 914 VAL A C 1 ATOM 6575 O O . VAL A 1 860 ? 145.971 533.244 45.088 1.00 27.39 ? 914 VAL A O 1 ATOM 6576 C CB . VAL A 1 860 ? 147.468 534.183 47.719 1.00 26.77 ? 914 VAL A CB 1 ATOM 6577 C CG1 . VAL A 1 860 ? 147.179 535.677 47.649 1.00 26.63 ? 914 VAL A CG1 1 ATOM 6578 C CG2 . VAL A 1 860 ? 148.101 533.844 49.056 1.00 26.23 ? 914 VAL A CG2 1 ATOM 6579 N N . VAL A 1 861 ? 144.479 534.492 46.229 1.00 24.01 ? 915 VAL A N 1 ATOM 6580 C CA . VAL A 1 861 ? 143.773 534.947 45.048 1.00 23.28 ? 915 VAL A CA 1 ATOM 6581 C C . VAL A 1 861 ? 143.930 536.467 45.043 1.00 28.91 ? 915 VAL A C 1 ATOM 6582 O O . VAL A 1 861 ? 143.474 537.107 45.979 1.00 27.42 ? 915 VAL A O 1 ATOM 6583 C CB . VAL A 1 861 ? 142.295 534.498 45.060 1.00 25.70 ? 915 VAL A CB 1 ATOM 6584 C CG1 . VAL A 1 861 ? 141.530 535.082 43.885 1.00 24.57 ? 915 VAL A CG1 1 ATOM 6585 C CG2 . VAL A 1 861 ? 142.176 532.975 45.077 1.00 25.38 ? 915 VAL A CG2 1 ATOM 6586 N N . ILE A 1 862 ? 144.639 537.031 44.035 1.00 27.87 ? 916 ILE A N 1 ATOM 6587 C CA . ILE A 1 862 ? 144.848 538.477 43.915 1.00 27.99 ? 916 ILE A CA 1 ATOM 6588 C C . ILE A 1 862 ? 144.040 539.025 42.732 1.00 34.49 ? 916 ILE A C 1 ATOM 6589 O O . ILE A 1 862 ? 144.197 538.601 41.583 1.00 34.43 ? 916 ILE A O 1 ATOM 6590 C CB . ILE A 1 862 ? 146.337 538.873 43.838 1.00 30.18 ? 916 ILE A CB 1 ATOM 6591 C CG1 . ILE A 1 862 ? 147.130 538.203 44.970 1.00 29.81 ? 916 ILE A CG1 1 ATOM 6592 C CG2 . ILE A 1 862 ? 146.476 540.396 43.890 1.00 31.21 ? 916 ILE A CG2 1 ATOM 6593 C CD1 . ILE A 1 862 ? 148.612 538.228 44.854 1.00 22.59 ? 916 ILE A CD1 1 ATOM 6594 N N . MET A 1 863 ? 143.106 539.899 43.058 1.00 31.62 ? 917 MET A N 1 ATOM 6595 C CA . MET A 1 863 ? 142.244 540.574 42.102 1.00 30.81 ? 917 MET A CA 1 ATOM 6596 C C . MET A 1 863 ? 142.874 541.949 41.816 1.00 32.48 ? 917 MET A C 1 ATOM 6597 O O . MET A 1 863 ? 143.182 542.695 42.756 1.00 29.86 ? 917 MET A O 1 ATOM 6598 C CB . MET A 1 863 ? 140.854 540.780 42.702 1.00 32.76 ? 917 MET A CB 1 ATOM 6599 C CG . MET A 1 863 ? 140.056 539.536 42.880 1.00 36.16 ? 917 MET A CG 1 ATOM 6600 S SD . MET A 1 863 ? 138.833 539.833 44.188 1.00 40.13 ? 917 MET A SD 1 ATOM 6601 C CE . MET A 1 863 ? 139.752 539.181 45.477 1.00 35.56 ? 917 MET A CE 1 ATOM 6602 N N . GLY A 1 864 ? 143.050 542.247 40.527 1.00 29.41 ? 918 GLY A N 1 ATOM 6603 C CA . GLY A 1 864 ? 143.643 543.490 40.036 1.00 29.51 ? 918 GLY A CA 1 ATOM 6604 C C . GLY A 1 864 ? 145.132 543.383 39.803 1.00 32.37 ? 918 GLY A C 1 ATOM 6605 O O . GLY A 1 864 ? 145.846 544.378 39.932 1.00 31.82 ? 918 GLY A O 1 ATOM 6606 N N . ALA A 1 865 ? 145.623 542.161 39.502 1.00 29.11 ? 919 ALA A N 1 ATOM 6607 C CA . ALA A 1 865 ? 147.064 541.947 39.334 1.00 28.18 ? 919 ALA A CA 1 ATOM 6608 C C . ALA A 1 865 ? 147.474 541.534 37.937 1.00 31.82 ? 919 ALA A C 1 ATOM 6609 O O . ALA A 1 865 ? 146.702 540.871 37.234 1.00 31.27 ? 919 ALA A O 1 ATOM 6610 C CB . ALA A 1 865 ? 147.586 540.956 40.358 1.00 28.05 ? 919 ALA A CB 1 ATOM 6611 N N . GLY A 1 866 ? 148.682 541.954 37.550 1.00 27.73 ? 920 GLY A N 1 ATOM 6612 C CA . GLY A 1 866 ? 149.291 541.583 36.280 1.00 28.05 ? 920 GLY A CA 1 ATOM 6613 C C . GLY A 1 866 ? 149.890 540.196 36.388 1.00 33.44 ? 920 GLY A C 1 ATOM 6614 O O . GLY A 1 866 ? 149.941 539.614 37.480 1.00 32.44 ? 920 GLY A O 1 ATOM 6615 N N . LYS A 1 867 ? 150.345 539.654 35.256 1.00 31.21 ? 921 LYS A N 1 ATOM 6616 C CA . LYS A 1 867 ? 150.928 538.324 35.257 1.00 30.51 ? 921 LYS A CA 1 ATOM 6617 C C . LYS A 1 867 ? 152.393 538.464 35.624 1.00 34.97 ? 921 LYS A C 1 ATOM 6618 O O . LYS A 1 867 ? 153.152 539.158 34.931 1.00 34.81 ? 921 LYS A O 1 ATOM 6619 C CB . LYS A 1 867 ? 150.766 537.649 33.891 1.00 31.28 ? 921 LYS A CB 1 ATOM 6620 C CG . LYS A 1 867 ? 151.227 536.194 33.848 1.00 36.67 ? 921 LYS A CG 1 ATOM 6621 C CD . LYS A 1 867 ? 151.175 535.688 32.419 1.00 54.29 ? 921 LYS A CD 1 ATOM 6622 C CE . LYS A 1 867 ? 152.350 534.806 32.068 1.00 74.47 ? 921 LYS A CE 1 ATOM 6623 N NZ . LYS A 1 867 ? 152.303 533.508 32.792 1.00 87.07 ? 921 LYS A NZ 1 ATOM 6624 N N . PRO A 1 868 ? 152.820 537.832 36.720 1.00 29.73 ? 922 PRO A N 1 ATOM 6625 C CA . PRO A 1 868 ? 154.237 537.904 37.059 1.00 29.87 ? 922 PRO A CA 1 ATOM 6626 C C . PRO A 1 868 ? 155.062 536.928 36.209 1.00 34.04 ? 922 PRO A C 1 ATOM 6627 O O . PRO A 1 868 ? 154.520 536.100 35.467 1.00 31.86 ? 922 PRO A O 1 ATOM 6628 C CB . PRO A 1 868 ? 154.254 537.498 38.531 1.00 31.10 ? 922 PRO A CB 1 ATOM 6629 C CG . PRO A 1 868 ? 153.106 536.579 38.675 1.00 34.42 ? 922 PRO A CG 1 ATOM 6630 C CD . PRO A 1 868 ? 152.082 536.954 37.648 1.00 29.91 ? 922 PRO A CD 1 ATOM 6631 N N . ALA A 1 869 ? 156.382 537.028 36.349 1.00 31.73 ? 923 ALA A N 1 ATOM 6632 C CA . ALA A 1 869 ? 157.358 536.131 35.734 1.00 31.68 ? 923 ALA A CA 1 ATOM 6633 C C . ALA A 1 869 ? 157.692 535.060 36.756 1.00 36.48 ? 923 ALA A C 1 ATOM 6634 O O . ALA A 1 869 ? 158.018 533.939 36.393 1.00 38.48 ? 923 ALA A O 1 ATOM 6635 C CB . ALA A 1 869 ? 158.629 536.889 35.367 1.00 31.94 ? 923 ALA A CB 1 ATOM 6636 N N . ALA A 1 870 ? 157.666 535.414 38.027 1.00 31.40 ? 924 ALA A N 1 ATOM 6637 C CA . ALA A 1 870 ? 157.995 534.479 39.094 1.00 31.38 ? 924 ALA A CA 1 ATOM 6638 C C . ALA A 1 870 ? 157.382 534.931 40.407 1.00 32.62 ? 924 ALA A C 1 ATOM 6639 O O . ALA A 1 870 ? 157.148 536.128 40.631 1.00 32.50 ? 924 ALA A O 1 ATOM 6640 C CB . ALA A 1 870 ? 159.515 534.341 39.240 1.00 32.12 ? 924 ALA A CB 1 ATOM 6641 N N . VAL A 1 871 ? 157.127 533.947 41.268 1.00 26.27 ? 925 VAL A N 1 ATOM 6642 C CA . VAL A 1 871 ? 156.526 534.122 42.587 1.00 24.55 ? 925 VAL A CA 1 ATOM 6643 C C . VAL A 1 871 ? 157.386 533.424 43.614 1.00 28.28 ? 925 VAL A C 1 ATOM 6644 O O . VAL A 1 871 ? 157.620 532.216 43.524 1.00 27.49 ? 925 VAL A O 1 ATOM 6645 C CB . VAL A 1 871 ? 155.072 533.640 42.609 1.00 25.78 ? 925 VAL A CB 1 ATOM 6646 C CG1 . VAL A 1 871 ? 154.494 533.760 44.009 1.00 25.35 ? 925 VAL A CG1 1 ATOM 6647 C CG2 . VAL A 1 871 ? 154.232 534.434 41.621 1.00 24.52 ? 925 VAL A CG2 1 ATOM 6648 N N . VAL A 1 872 ? 157.872 534.203 44.570 1.00 26.24 ? 926 VAL A N 1 ATOM 6649 C CA . VAL A 1 872 ? 158.799 533.736 45.580 1.00 27.09 ? 926 VAL A CA 1 ATOM 6650 C C . VAL A 1 872 ? 158.233 533.910 46.967 1.00 30.59 ? 926 VAL A C 1 ATOM 6651 O O . VAL A 1 872 ? 157.792 535.006 47.327 1.00 29.85 ? 926 VAL A O 1 ATOM 6652 C CB . VAL A 1 872 ? 160.120 534.523 45.412 1.00 32.09 ? 926 VAL A CB 1 ATOM 6653 C CG1 . VAL A 1 872 ? 161.046 534.310 46.584 1.00 32.50 ? 926 VAL A CG1 1 ATOM 6654 C CG2 . VAL A 1 872 ? 160.815 534.176 44.113 1.00 31.69 ? 926 VAL A CG2 1 ATOM 6655 N N . LEU A 1 873 ? 158.272 532.835 47.761 1.00 27.14 ? 927 LEU A N 1 ATOM 6656 C CA . LEU A 1 873 ? 157.844 532.866 49.157 1.00 26.63 ? 927 LEU A CA 1 ATOM 6657 C C . LEU A 1 873 ? 159.061 532.763 50.088 1.00 31.74 ? 927 LEU A C 1 ATOM 6658 O O . LEU A 1 873 ? 159.868 531.833 49.955 1.00 31.63 ? 927 LEU A O 1 ATOM 6659 C CB . LEU A 1 873 ? 156.806 531.761 49.488 1.00 26.52 ? 927 LEU A CB 1 ATOM 6660 C CG . LEU A 1 873 ? 156.194 531.842 50.922 1.00 32.31 ? 927 LEU A CG 1 ATOM 6661 C CD1 . LEU A 1 873 ? 154.806 531.353 50.968 1.00 32.56 ? 927 LEU A CD1 1 ATOM 6662 C CD2 . LEU A 1 873 ? 156.972 531.040 51.938 1.00 35.89 ? 927 LEU A CD2 1 ATOM 6663 N N . GLN A 1 874 ? 159.146 533.681 51.063 1.00 28.79 ? 928 GLN A N 1 ATOM 6664 C CA . GLN A 1 874 ? 160.171 533.677 52.114 1.00 29.82 ? 928 GLN A CA 1 ATOM 6665 C C . GLN A 1 874 ? 159.553 533.518 53.489 1.00 33.20 ? 928 GLN A C 1 ATOM 6666 O O . GLN A 1 874 ? 158.567 534.177 53.802 1.00 32.84 ? 928 GLN A O 1 ATOM 6667 C CB . GLN A 1 874 ? 161.000 534.964 52.106 1.00 31.91 ? 928 GLN A CB 1 ATOM 6668 C CG . GLN A 1 874 ? 161.890 535.058 50.881 1.00 58.72 ? 928 GLN A CG 1 ATOM 6669 C CD . GLN A 1 874 ? 162.756 536.292 50.854 1.00 84.58 ? 928 GLN A CD 1 ATOM 6670 O OE1 . GLN A 1 874 ? 162.440 537.335 51.447 1.00 83.52 ? 928 GLN A OE1 1 ATOM 6671 N NE2 . GLN A 1 874 ? 163.856 536.208 50.115 1.00 72.19 ? 928 GLN A NE2 1 ATOM 6672 N N . THR A 1 875 ? 160.142 532.671 54.320 1.00 29.16 ? 929 THR A N 1 ATOM 6673 C CA . THR A 1 875 ? 159.673 532.466 55.687 1.00 29.23 ? 929 THR A CA 1 ATOM 6674 C C . THR A 1 875 ? 160.818 531.911 56.519 1.00 35.14 ? 929 THR A C 1 ATOM 6675 O O . THR A 1 875 ? 161.546 531.023 56.064 1.00 35.61 ? 929 THR A O 1 ATOM 6676 C CB . THR A 1 875 ? 158.361 531.653 55.747 1.00 27.37 ? 929 THR A CB 1 ATOM 6677 O OG1 . THR A 1 875 ? 157.805 531.770 57.047 1.00 28.05 ? 929 THR A OG1 1 ATOM 6678 C CG2 . THR A 1 875 ? 158.560 530.217 55.437 1.00 21.75 ? 929 THR A CG2 1 ATOM 6679 N N . LYS A 1 876 ? 160.989 532.436 57.726 1.00 32.57 ? 930 LYS A N 1 ATOM 6680 C CA . LYS A 1 876 ? 162.075 532.037 58.612 1.00 32.67 ? 930 LYS A CA 1 ATOM 6681 C C . LYS A 1 876 ? 162.015 530.543 58.893 1.00 36.54 ? 930 LYS A C 1 ATOM 6682 O O . LYS A 1 876 ? 160.948 530.029 59.232 1.00 36.88 ? 930 LYS A O 1 ATOM 6683 C CB . LYS A 1 876 ? 162.028 532.859 59.918 1.00 35.29 ? 930 LYS A CB 1 ATOM 6684 C CG . LYS A 1 876 ? 163.256 532.741 60.824 1.00 43.39 ? 930 LYS A CG 1 ATOM 6685 C CD . LYS A 1 876 ? 162.948 533.256 62.219 1.00 48.92 ? 930 LYS A CD 1 ATOM 6686 C CE . LYS A 1 876 ? 164.042 532.936 63.209 1.00 59.93 ? 930 LYS A CE 1 ATOM 6687 N NZ . LYS A 1 876 ? 165.086 533.998 63.248 1.00 61.02 ? 930 LYS A NZ 1 ATOM 6688 N N . GLY A 1 877 ? 163.149 529.865 58.713 1.00 31.33 ? 931 GLY A N 1 ATOM 6689 C CA . GLY A 1 877 ? 163.265 528.432 58.969 1.00 30.02 ? 931 GLY A CA 1 ATOM 6690 C C . GLY A 1 877 ? 163.135 527.543 57.749 1.00 32.79 ? 931 GLY A C 1 ATOM 6691 O O . GLY A 1 877 ? 163.378 526.335 57.843 1.00 32.19 ? 931 GLY A O 1 ATOM 6692 N N . SER A 1 878 ? 162.751 528.134 56.592 1.00 28.50 ? 932 SER A N 1 ATOM 6693 C CA . SER A 1 878 ? 162.583 527.426 55.323 1.00 27.72 ? 932 SER A CA 1 ATOM 6694 C C . SER A 1 878 ? 163.421 528.030 54.206 1.00 31.04 ? 932 SER A C 1 ATOM 6695 O O . SER A 1 878 ? 163.692 529.240 54.211 1.00 32.43 ? 932 SER A O 1 ATOM 6696 C CB . SER A 1 878 ? 161.112 527.427 54.905 1.00 30.11 ? 932 SER A CB 1 ATOM 6697 O OG . SER A 1 878 ? 160.269 526.912 55.929 1.00 30.41 ? 932 SER A OG 1 ATOM 6698 N N . PRO A 1 879 ? 163.826 527.239 53.196 1.00 25.92 ? 933 PRO A N 1 ATOM 6699 C CA . PRO A 1 879 ? 164.533 527.863 52.072 1.00 24.29 ? 933 PRO A CA 1 ATOM 6700 C C . PRO A 1 879 ? 163.503 528.653 51.284 1.00 27.38 ? 933 PRO A C 1 ATOM 6701 O O . PRO A 1 879 ? 162.294 528.430 51.407 1.00 24.36 ? 933 PRO A O 1 ATOM 6702 C CB . PRO A 1 879 ? 165.028 526.659 51.255 1.00 25.65 ? 933 PRO A CB 1 ATOM 6703 C CG . PRO A 1 879 ? 164.025 525.591 51.532 1.00 29.58 ? 933 PRO A CG 1 ATOM 6704 C CD . PRO A 1 879 ? 163.632 525.780 52.971 1.00 26.03 ? 933 PRO A CD 1 ATOM 6705 N N . GLU A 1 880 ? 163.989 529.559 50.454 1.00 26.65 ? 934 GLU A N 1 ATOM 6706 C CA . GLU A 1 880 ? 163.150 530.344 49.568 1.00 25.85 ? 934 GLU A CA 1 ATOM 6707 C C . GLU A 1 880 ? 162.376 529.368 48.657 1.00 27.25 ? 934 GLU A C 1 ATOM 6708 O O . GLU A 1 880 ? 162.893 528.331 48.220 1.00 23.22 ? 934 GLU A O 1 ATOM 6709 C CB . GLU A 1 880 ? 164.023 531.320 48.790 1.00 27.28 ? 934 GLU A CB 1 ATOM 6710 C CG . GLU A 1 880 ? 163.261 532.257 47.899 1.00 38.36 ? 934 GLU A CG 1 ATOM 6711 C CD . GLU A 1 880 ? 164.190 533.265 47.259 1.00 61.89 ? 934 GLU A CD 1 ATOM 6712 O OE1 . GLU A 1 880 ? 164.568 534.236 47.953 1.00 53.07 ? 934 GLU A OE1 1 ATOM 6713 O OE2 . GLU A 1 880 ? 164.549 533.081 46.074 1.00 59.38 ? 934 GLU A OE2 1 ATOM 6714 N N . SER A 1 881 ? 161.101 529.660 48.472 1.00 25.56 ? 935 SER A N 1 ATOM 6715 C CA . SER A 1 881 ? 160.247 528.790 47.709 1.00 25.00 ? 935 SER A CA 1 ATOM 6716 C C . SER A 1 881 ? 159.715 529.487 46.478 1.00 27.14 ? 935 SER A C 1 ATOM 6717 O O . SER A 1 881 ? 159.515 530.694 46.495 1.00 25.99 ? 935 SER A O 1 ATOM 6718 C CB . SER A 1 881 ? 159.131 528.261 48.612 1.00 28.72 ? 935 SER A CB 1 ATOM 6719 O OG . SER A 1 881 ? 158.024 527.740 47.904 1.00 37.26 ? 935 SER A OG 1 ATOM 6720 N N . ARG A 1 882 ? 159.530 528.723 45.399 1.00 25.15 ? 936 ARG A N 1 ATOM 6721 C CA . ARG A 1 882 ? 158.957 529.218 44.144 1.00 26.18 ? 936 ARG A CA 1 ATOM 6722 C C . ARG A 1 882 ? 157.578 528.599 44.005 1.00 31.87 ? 936 ARG A C 1 ATOM 6723 O O . ARG A 1 882 ? 157.414 527.363 44.101 1.00 31.79 ? 936 ARG A O 1 ATOM 6724 C CB . ARG A 1 882 ? 159.819 528.841 42.933 1.00 25.49 ? 936 ARG A CB 1 ATOM 6725 C CG . ARG A 1 882 ? 161.064 529.701 42.767 1.00 32.12 ? 936 ARG A CG 1 ATOM 6726 C CD . ARG A 1 882 ? 160.788 531.071 42.167 1.00 35.42 ? 936 ARG A CD 1 ATOM 6727 N NE . ARG A 1 882 ? 160.268 531.030 40.793 1.00 36.78 ? 936 ARG A NE 1 ATOM 6728 C CZ . ARG A 1 882 ? 161.028 531.042 39.698 1.00 51.14 ? 936 ARG A CZ 1 ATOM 6729 N NH1 . ARG A 1 882 ? 162.353 531.075 39.799 1.00 34.17 ? 936 ARG A NH1 1 ATOM 6730 N NH2 . ARG A 1 882 ? 160.471 531.009 38.496 1.00 36.79 ? 936 ARG A NH2 1 ATOM 6731 N N . LEU A 1 883 ? 156.581 529.462 43.818 1.00 26.97 ? 937 LEU A N 1 ATOM 6732 C CA . LEU A 1 883 ? 155.207 529.012 43.688 1.00 26.04 ? 937 LEU A CA 1 ATOM 6733 C C . LEU A 1 883 ? 154.752 529.013 42.258 1.00 31.33 ? 937 LEU A C 1 ATOM 6734 O O . LEU A 1 883 ? 155.098 529.909 41.497 1.00 31.02 ? 937 LEU A O 1 ATOM 6735 C CB . LEU A 1 883 ? 154.284 529.913 44.501 1.00 25.21 ? 937 LEU A CB 1 ATOM 6736 C CG . LEU A 1 883 ? 154.612 530.097 45.973 1.00 27.25 ? 937 LEU A CG 1 ATOM 6737 C CD1 . LEU A 1 883 ? 153.618 531.029 46.590 1.00 26.77 ? 937 LEU A CD1 1 ATOM 6738 C CD2 . LEU A 1 883 ? 154.666 528.742 46.718 1.00 22.45 ? 937 LEU A CD2 1 ATOM 6739 N N . SER A 1 884 ? 153.951 528.024 41.878 1.00 28.96 ? 938 SER A N 1 ATOM 6740 C CA . SER A 1 884 ? 153.390 528.056 40.546 1.00 27.73 ? 938 SER A CA 1 ATOM 6741 C C . SER A 1 884 ? 152.125 528.910 40.672 1.00 28.76 ? 938 SER A C 1 ATOM 6742 O O . SER A 1 884 ? 151.658 529.201 41.786 1.00 27.88 ? 938 SER A O 1 ATOM 6743 C CB . SER A 1 884 ? 153.117 526.656 40.029 1.00 31.62 ? 938 SER A CB 1 ATOM 6744 O OG . SER A 1 884 ? 152.034 526.113 40.748 1.00 48.61 ? 938 SER A OG 1 ATOM 6745 N N . PHE A 1 885 ? 151.646 529.408 39.557 1.00 23.20 ? 939 PHE A N 1 ATOM 6746 C CA . PHE A 1 885 ? 150.525 530.327 39.575 1.00 22.72 ? 939 PHE A CA 1 ATOM 6747 C C . PHE A 1 885 ? 149.761 530.233 38.277 1.00 28.50 ? 939 PHE A C 1 ATOM 6748 O O . PHE A 1 885 ? 150.252 529.702 37.261 1.00 28.04 ? 939 PHE A O 1 ATOM 6749 C CB . PHE A 1 885 ? 151.019 531.796 39.828 1.00 23.78 ? 939 PHE A CB 1 ATOM 6750 C CG . PHE A 1 885 ? 152.074 532.280 38.854 1.00 23.64 ? 939 PHE A CG 1 ATOM 6751 C CD1 . PHE A 1 885 ? 153.420 532.012 39.072 1.00 27.21 ? 939 PHE A CD1 1 ATOM 6752 C CD2 . PHE A 1 885 ? 151.711 532.897 37.665 1.00 23.98 ? 939 PHE A CD2 1 ATOM 6753 C CE1 . PHE A 1 885 ? 154.386 532.401 38.138 1.00 28.30 ? 939 PHE A CE1 1 ATOM 6754 C CE2 . PHE A 1 885 ? 152.673 533.304 36.739 1.00 26.38 ? 939 PHE A CE2 1 ATOM 6755 C CZ . PHE A 1 885 ? 154.000 533.055 36.977 1.00 26.18 ? 939 PHE A CZ 1 ATOM 6756 N N . GLN A 1 886 ? 148.532 530.735 38.335 1.00 25.80 ? 940 GLN A N 1 ATOM 6757 C CA . GLN A 1 886 ? 147.627 530.833 37.195 1.00 25.25 ? 940 GLN A CA 1 ATOM 6758 C C . GLN A 1 886 ? 147.112 532.270 37.113 1.00 28.40 ? 940 GLN A C 1 ATOM 6759 O O . GLN A 1 886 ? 146.832 532.909 38.136 1.00 24.52 ? 940 GLN A O 1 ATOM 6760 C CB . GLN A 1 886 ? 146.471 529.831 37.294 1.00 25.92 ? 940 GLN A CB 1 ATOM 6761 C CG . GLN A 1 886 ? 146.941 528.400 37.476 1.00 30.26 ? 940 GLN A CG 1 ATOM 6762 C CD . GLN A 1 886 ? 146.229 527.394 36.595 1.00 63.72 ? 940 GLN A CD 1 ATOM 6763 O OE1 . GLN A 1 886 ? 145.750 527.688 35.485 1.00 58.82 ? 940 GLN A OE1 1 ATOM 6764 N NE2 . GLN A 1 886 ? 146.232 526.143 37.031 1.00 67.04 ? 940 GLN A NE2 1 ATOM 6765 N N . HIS A 1 887 ? 146.999 532.778 35.884 1.00 26.78 ? 941 HIS A N 1 ATOM 6766 C CA . HIS A 1 887 ? 146.551 534.136 35.674 1.00 27.04 ? 941 HIS A CA 1 ATOM 6767 C C . HIS A 1 887 ? 145.519 534.235 34.559 1.00 30.87 ? 941 HIS A C 1 ATOM 6768 O O . HIS A 1 887 ? 145.719 533.684 33.479 1.00 29.73 ? 941 HIS A O 1 ATOM 6769 C CB . HIS A 1 887 ? 147.764 535.055 35.443 1.00 28.33 ? 941 HIS A CB 1 ATOM 6770 C CG . HIS A 1 887 ? 147.424 536.505 35.318 1.00 32.29 ? 941 HIS A CG 1 ATOM 6771 N ND1 . HIS A 1 887 ? 147.155 537.083 34.088 1.00 34.78 ? 941 HIS A ND1 1 ATOM 6772 C CD2 . HIS A 1 887 ? 147.325 537.451 36.272 1.00 34.21 ? 941 HIS A CD2 1 ATOM 6773 C CE1 . HIS A 1 887 ? 146.861 538.348 34.340 1.00 34.12 ? 941 HIS A CE1 1 ATOM 6774 N NE2 . HIS A 1 887 ? 146.964 538.617 35.638 1.00 34.32 ? 941 HIS A NE2 1 ATOM 6775 N N . ASP A 1 888 ? 144.415 534.946 34.835 1.00 27.92 ? 942 ASP A N 1 ATOM 6776 C CA . ASP A 1 888 ? 143.380 535.217 33.851 1.00 28.11 ? 942 ASP A CA 1 ATOM 6777 C C . ASP A 1 888 ? 143.579 536.684 33.367 1.00 34.12 ? 942 ASP A C 1 ATOM 6778 O O . ASP A 1 888 ? 143.292 537.619 34.119 1.00 32.98 ? 942 ASP A O 1 ATOM 6779 C CB . ASP A 1 888 ? 141.971 534.984 34.419 1.00 29.23 ? 942 ASP A CB 1 ATOM 6780 C CG . ASP A 1 888 ? 140.847 535.213 33.414 1.00 42.24 ? 942 ASP A CG 1 ATOM 6781 O OD1 . ASP A 1 888 ? 141.067 535.952 32.421 1.00 43.19 ? 942 ASP A OD1 1 ATOM 6782 O OD2 . ASP A 1 888 ? 139.740 534.692 33.636 1.00 48.74 ? 942 ASP A OD2 1 ATOM 6783 N N . PRO A 1 889 ? 144.065 536.905 32.114 1.00 32.09 ? 943 PRO A N 1 ATOM 6784 C CA . PRO A 1 889 ? 144.325 538.293 31.653 1.00 32.94 ? 943 PRO A CA 1 ATOM 6785 C C . PRO A 1 889 ? 143.082 539.181 31.451 1.00 39.05 ? 943 PRO A C 1 ATOM 6786 O O . PRO A 1 889 ? 143.164 540.411 31.525 1.00 37.26 ? 943 PRO A O 1 ATOM 6787 C CB . PRO A 1 889 ? 145.103 538.088 30.354 1.00 34.23 ? 943 PRO A CB 1 ATOM 6788 C CG . PRO A 1 889 ? 144.649 536.744 29.862 1.00 37.15 ? 943 PRO A CG 1 ATOM 6789 C CD . PRO A 1 889 ? 144.425 535.915 31.077 1.00 32.51 ? 943 PRO A CD 1 ATOM 6790 N N . GLU A 1 890 ? 141.942 538.544 31.201 1.00 39.23 ? 944 GLU A N 1 ATOM 6791 C CA . GLU A 1 890 ? 140.655 539.193 31.026 1.00 41.09 ? 944 GLU A CA 1 ATOM 6792 C C . GLU A 1 890 ? 140.203 539.833 32.362 1.00 47.20 ? 944 GLU A C 1 ATOM 6793 O O . GLU A 1 890 ? 139.784 540.987 32.369 1.00 47.38 ? 944 GLU A O 1 ATOM 6794 C CB . GLU A 1 890 ? 139.668 538.134 30.533 1.00 43.00 ? 944 GLU A CB 1 ATOM 6795 C CG . GLU A 1 890 ? 138.273 538.601 30.166 1.00 56.67 ? 944 GLU A CG 1 ATOM 6796 C CD . GLU A 1 890 ? 137.256 537.471 30.144 1.00 80.40 ? 944 GLU A CD 1 ATOM 6797 O OE1 . GLU A 1 890 ? 137.648 536.310 29.871 1.00 53.10 ? 944 GLU A OE1 1 ATOM 6798 O OE2 . GLU A 1 890 ? 136.065 537.747 30.421 1.00 82.72 ? 944 GLU A OE2 1 ATOM 6799 N N . THR A 1 891 ? 140.366 539.116 33.491 1.00 44.45 ? 945 THR A N 1 ATOM 6800 C CA . THR A 1 891 ? 139.945 539.600 34.817 1.00 43.54 ? 945 THR A CA 1 ATOM 6801 C C . THR A 1 891 ? 141.031 540.180 35.674 1.00 45.52 ? 945 THR A C 1 ATOM 6802 O O . THR A 1 891 ? 140.720 540.812 36.692 1.00 46.58 ? 945 THR A O 1 ATOM 6803 C CB . THR A 1 891 ? 139.232 538.495 35.608 1.00 47.43 ? 945 THR A CB 1 ATOM 6804 O OG1 . THR A 1 891 ? 140.082 537.351 35.737 1.00 49.57 ? 945 THR A OG1 1 ATOM 6805 C CG2 . THR A 1 891 ? 137.933 538.105 34.982 1.00 42.27 ? 945 THR A CG2 1 ATOM 6806 N N . SER A 1 892 ? 142.298 539.963 35.301 1.00 37.95 ? 946 SER A N 1 ATOM 6807 C CA . SER A 1 892 ? 143.448 540.355 36.115 1.00 35.28 ? 946 SER A CA 1 ATOM 6808 C C . SER A 1 892 ? 143.400 539.618 37.477 1.00 36.14 ? 946 SER A C 1 ATOM 6809 O O . SER A 1 892 ? 143.600 540.211 38.540 1.00 35.88 ? 946 SER A O 1 ATOM 6810 C CB . SER A 1 892 ? 143.533 541.869 36.303 1.00 36.04 ? 946 SER A CB 1 ATOM 6811 O OG . SER A 1 892 ? 143.820 542.547 35.099 1.00 38.75 ? 946 SER A OG 1 ATOM 6812 N N . VAL A 1 893 ? 143.138 538.319 37.433 1.00 31.45 ? 947 VAL A N 1 ATOM 6813 C CA . VAL A 1 893 ? 143.098 537.491 38.631 1.00 30.19 ? 947 VAL A CA 1 ATOM 6814 C C . VAL A 1 893 ? 144.271 536.551 38.600 1.00 32.27 ? 947 VAL A C 1 ATOM 6815 O O . VAL A 1 893 ? 144.465 535.842 37.610 1.00 34.16 ? 947 VAL A O 1 ATOM 6816 C CB . VAL A 1 893 ? 141.743 536.769 38.796 1.00 33.61 ? 947 VAL A CB 1 ATOM 6817 C CG1 . VAL A 1 893 ? 141.775 535.776 39.972 1.00 33.25 ? 947 VAL A CG1 1 ATOM 6818 C CG2 . VAL A 1 893 ? 140.632 537.789 38.998 1.00 33.03 ? 947 VAL A CG2 1 ATOM 6819 N N . LEU A 1 894 ? 145.064 536.578 39.674 1.00 25.42 ? 948 LEU A N 1 ATOM 6820 C CA . LEU A 1 894 ? 146.257 535.782 39.866 1.00 23.15 ? 948 LEU A CA 1 ATOM 6821 C C . LEU A 1 894 ? 146.010 534.844 41.019 1.00 28.36 ? 948 LEU A C 1 ATOM 6822 O O . LEU A 1 894 ? 145.584 535.283 42.085 1.00 28.36 ? 948 LEU A O 1 ATOM 6823 C CB . LEU A 1 894 ? 147.406 536.721 40.187 1.00 22.58 ? 948 LEU A CB 1 ATOM 6824 C CG . LEU A 1 894 ? 148.760 536.099 40.440 1.00 26.25 ? 948 LEU A CG 1 ATOM 6825 C CD1 . LEU A 1 894 ? 149.237 535.352 39.214 1.00 25.69 ? 948 LEU A CD1 1 ATOM 6826 C CD2 . LEU A 1 894 ? 149.744 537.161 40.845 1.00 27.43 ? 948 LEU A CD2 1 ATOM 6827 N N . ILE A 1 895 ? 146.231 533.546 40.799 1.00 25.40 ? 949 ILE A N 1 ATOM 6828 C CA . ILE A 1 895 ? 146.036 532.527 41.810 1.00 24.41 ? 949 ILE A CA 1 ATOM 6829 C C . ILE A 1 895 ? 147.383 531.947 42.110 1.00 28.71 ? 949 ILE A C 1 ATOM 6830 O O . ILE A 1 895 ? 148.011 531.398 41.211 1.00 28.19 ? 949 ILE A O 1 ATOM 6831 C CB . ILE A 1 895 ? 145.047 531.422 41.349 1.00 27.03 ? 949 ILE A CB 1 ATOM 6832 C CG1 . ILE A 1 895 ? 143.656 532.032 41.039 1.00 26.53 ? 949 ILE A CG1 1 ATOM 6833 C CG2 . ILE A 1 895 ? 144.967 530.307 42.417 1.00 25.85 ? 949 ILE A CG2 1 ATOM 6834 C CD1 . ILE A 1 895 ? 142.703 531.154 40.248 1.00 30.67 ? 949 ILE A CD1 1 ATOM 6835 N N . LEU A 1 896 ? 147.825 532.054 43.368 1.00 24.15 ? 950 LEU A N 1 ATOM 6836 C CA . LEU A 1 896 ? 149.091 531.515 43.799 1.00 23.11 ? 950 LEU A CA 1 ATOM 6837 C C . LEU A 1 896 ? 148.829 530.177 44.397 1.00 29.88 ? 950 LEU A C 1 ATOM 6838 O O . LEU A 1 896 ? 148.034 530.069 45.326 1.00 33.10 ? 950 LEU A O 1 ATOM 6839 C CB . LEU A 1 896 ? 149.732 532.462 44.814 1.00 23.22 ? 950 LEU A CB 1 ATOM 6840 C CG . LEU A 1 896 ? 149.867 533.919 44.358 1.00 27.61 ? 950 LEU A CG 1 ATOM 6841 C CD1 . LEU A 1 896 ? 150.601 534.697 45.387 1.00 28.09 ? 950 LEU A CD1 1 ATOM 6842 C CD2 . LEU A 1 896 ? 150.610 534.036 43.004 1.00 26.04 ? 950 LEU A CD2 1 ATOM 6843 N N . ARG A 1 897 ? 149.506 529.148 43.895 1.00 26.08 ? 951 ARG A N 1 ATOM 6844 C CA . ARG A 1 897 ? 149.315 527.765 44.334 1.00 24.96 ? 951 ARG A CA 1 ATOM 6845 C C . ARG A 1 897 ? 150.060 527.412 45.577 1.00 29.34 ? 951 ARG A C 1 ATOM 6846 O O . ARG A 1 897 ? 151.288 527.561 45.640 1.00 30.18 ? 951 ARG A O 1 ATOM 6847 C CB . ARG A 1 897 ? 149.715 526.775 43.199 1.00 22.67 ? 951 ARG A CB 1 ATOM 6848 C CG . ARG A 1 897 ? 149.617 525.304 43.564 1.00 25.44 ? 951 ARG A CG 1 ATOM 6849 C CD . ARG A 1 897 ? 150.172 524.351 42.527 1.00 31.04 ? 951 ARG A CD 1 ATOM 6850 N NE . ARG A 1 897 ? 149.879 522.978 42.918 1.00 26.99 ? 951 ARG A NE 1 ATOM 6851 C CZ . ARG A 1 897 ? 150.591 522.283 43.792 1.00 39.19 ? 951 ARG A CZ 1 ATOM 6852 N NH1 . ARG A 1 897 ? 150.196 521.074 44.165 1.00 27.31 ? 951 ARG A NH1 1 ATOM 6853 N NH2 . ARG A 1 897 ? 151.665 522.817 44.358 1.00 20.94 ? 951 ARG A NH2 1 ATOM 6854 N N . LYS A 1 898 ? 149.329 526.854 46.539 1.00 25.47 ? 952 LYS A N 1 ATOM 6855 C CA . LYS A 1 898 ? 149.874 526.197 47.713 1.00 24.80 ? 952 LYS A CA 1 ATOM 6856 C C . LYS A 1 898 ? 151.093 526.880 48.353 1.00 27.82 ? 952 LYS A C 1 ATOM 6857 O O . LYS A 1 898 ? 152.141 526.240 48.488 1.00 30.05 ? 952 LYS A O 1 ATOM 6858 C CB . LYS A 1 898 ? 150.198 524.724 47.338 1.00 26.11 ? 952 LYS A CB 1 ATOM 6859 C CG . LYS A 1 898 ? 150.335 523.774 48.503 1.00 24.03 ? 952 LYS A CG 1 ATOM 6860 C CD . LYS A 1 898 ? 150.805 522.373 48.071 1.00 25.26 ? 952 LYS A CD 1 ATOM 6861 C CE . LYS A 1 898 ? 150.923 521.419 49.237 1.00 17.76 ? 952 LYS A CE 1 ATOM 6862 N NZ . LYS A 1 898 ? 151.731 520.252 48.838 1.00 30.63 ? 952 LYS A NZ 1 ATOM 6863 N N . PRO A 1 899 ? 150.982 528.123 48.847 1.00 21.99 ? 953 PRO A N 1 ATOM 6864 C CA . PRO A 1 899 ? 152.102 528.691 49.621 1.00 21.94 ? 953 PRO A CA 1 ATOM 6865 C C . PRO A 1 899 ? 152.660 527.698 50.677 1.00 24.76 ? 953 PRO A C 1 ATOM 6866 O O . PRO A 1 899 ? 153.879 527.599 50.836 1.00 24.08 ? 953 PRO A O 1 ATOM 6867 C CB . PRO A 1 899 ? 151.476 529.926 50.262 1.00 23.13 ? 953 PRO A CB 1 ATOM 6868 C CG . PRO A 1 899 ? 150.439 530.352 49.267 1.00 26.74 ? 953 PRO A CG 1 ATOM 6869 C CD . PRO A 1 899 ? 149.855 529.076 48.769 1.00 22.74 ? 953 PRO A CD 1 ATOM 6870 N N . GLY A 1 900 ? 151.765 526.964 51.352 1.00 21.49 ? 954 GLY A N 1 ATOM 6871 C CA . GLY A 1 900 ? 152.102 525.909 52.306 1.00 21.95 ? 954 GLY A CA 1 ATOM 6872 C C . GLY A 1 900 ? 152.724 526.351 53.601 1.00 24.90 ? 954 GLY A C 1 ATOM 6873 O O . GLY A 1 900 ? 153.311 525.545 54.313 1.00 24.73 ? 954 GLY A O 1 ATOM 6874 N N . VAL A 1 901 ? 152.562 527.603 53.924 1.00 22.51 ? 955 VAL A N 1 ATOM 6875 C CA . VAL A 1 901 ? 153.152 528.179 55.117 1.00 22.03 ? 955 VAL A CA 1 ATOM 6876 C C . VAL A 1 901 ? 152.144 528.201 56.277 1.00 24.89 ? 955 VAL A C 1 ATOM 6877 O O . VAL A 1 901 ? 150.948 528.410 56.058 1.00 22.83 ? 955 VAL A O 1 ATOM 6878 C CB . VAL A 1 901 ? 153.751 529.573 54.773 1.00 24.02 ? 955 VAL A CB 1 ATOM 6879 C CG1 . VAL A 1 901 ? 152.689 530.555 54.274 1.00 22.17 ? 955 VAL A CG1 1 ATOM 6880 C CG2 . VAL A 1 901 ? 154.548 530.132 55.941 1.00 24.85 ? 955 VAL A CG2 1 ATOM 6881 N N . SER A 1 902 ? 152.633 527.983 57.500 1.00 20.53 ? 956 SER A N 1 ATOM 6882 C CA . SER A 1 902 ? 151.837 528.095 58.706 1.00 18.52 ? 956 SER A CA 1 ATOM 6883 C C . SER A 1 902 ? 151.259 529.516 58.859 1.00 22.93 ? 956 SER A C 1 ATOM 6884 O O . SER A 1 902 ? 151.986 530.501 58.708 1.00 23.63 ? 956 SER A O 1 ATOM 6885 C CB . SER A 1 902 ? 152.693 527.787 59.924 1.00 18.83 ? 956 SER A CB 1 ATOM 6886 O OG . SER A 1 902 ? 151.959 528.012 61.120 1.00 27.38 ? 956 SER A OG 1 ATOM 6887 N N . VAL A 1 903 ? 149.978 529.611 59.264 1.00 18.38 ? 957 VAL A N 1 ATOM 6888 C CA . VAL A 1 903 ? 149.318 530.896 59.552 1.00 17.42 ? 957 VAL A CA 1 ATOM 6889 C C . VAL A 1 903 ? 149.988 531.592 60.769 1.00 21.88 ? 957 VAL A C 1 ATOM 6890 O O . VAL A 1 903 ? 149.838 532.801 60.951 1.00 22.10 ? 957 VAL A O 1 ATOM 6891 C CB . VAL A 1 903 ? 147.786 530.715 59.764 1.00 20.68 ? 957 VAL A CB 1 ATOM 6892 C CG1 . VAL A 1 903 ? 147.473 530.083 61.103 1.00 20.52 ? 957 VAL A CG1 1 ATOM 6893 C CG2 . VAL A 1 903 ? 147.028 532.033 59.634 1.00 20.02 ? 957 VAL A CG2 1 ATOM 6894 N N . ALA A 1 904 ? 150.702 530.822 61.606 1.00 16.87 ? 958 ALA A N 1 ATOM 6895 C CA . ALA A 1 904 ? 151.357 531.356 62.782 1.00 16.32 ? 958 ALA A CA 1 ATOM 6896 C C . ALA A 1 904 ? 152.698 532.046 62.473 1.00 20.76 ? 958 ALA A C 1 ATOM 6897 O O . ALA A 1 904 ? 153.212 532.767 63.321 1.00 20.87 ? 958 ALA A O 1 ATOM 6898 C CB . ALA A 1 904 ? 151.540 530.255 63.806 1.00 17.15 ? 958 ALA A CB 1 ATOM 6899 N N . SER A 1 905 ? 153.235 531.859 61.265 1.00 18.54 ? 959 SER A N 1 ATOM 6900 C CA . SER A 1 905 ? 154.529 532.414 60.870 1.00 19.08 ? 959 SER A CA 1 ATOM 6901 C C . SER A 1 905 ? 154.433 533.720 60.121 1.00 25.89 ? 959 SER A C 1 ATOM 6902 O O . SER A 1 905 ? 153.521 533.912 59.312 1.00 23.69 ? 959 SER A O 1 ATOM 6903 C CB . SER A 1 905 ? 155.265 531.450 59.927 1.00 21.59 ? 959 SER A CB 1 ATOM 6904 O OG . SER A 1 905 ? 155.431 530.150 60.451 1.00 28.76 ? 959 SER A OG 1 ATOM 6905 N N . ASP A 1 906 ? 155.466 534.550 60.277 1.00 26.86 ? 960 ASP A N 1 ATOM 6906 C CA . ASP A 1 906 ? 155.685 535.714 59.435 1.00 28.06 ? 960 ASP A CA 1 ATOM 6907 C C . ASP A 1 906 ? 156.177 535.178 58.098 1.00 32.46 ? 960 ASP A C 1 ATOM 6908 O O . ASP A 1 906 ? 156.941 534.203 58.075 1.00 32.04 ? 960 ASP A O 1 ATOM 6909 C CB . ASP A 1 906 ? 156.778 536.613 60.029 1.00 30.72 ? 960 ASP A CB 1 ATOM 6910 C CG . ASP A 1 906 ? 156.381 537.320 61.314 1.00 40.54 ? 960 ASP A CG 1 ATOM 6911 O OD1 . ASP A 1 906 ? 155.183 537.361 61.625 1.00 38.67 ? 960 ASP A OD1 1 ATOM 6912 O OD2 . ASP A 1 906 ? 157.269 537.859 61.988 1.00 48.79 ? 960 ASP A OD2 1 ATOM 6913 N N . TRP A 1 907 ? 155.706 535.766 56.993 1.00 29.02 ? 961 TRP A N 1 ATOM 6914 C CA . TRP A 1 907 ? 156.139 535.367 55.657 1.00 28.91 ? 961 TRP A CA 1 ATOM 6915 C C . TRP A 1 907 ? 155.925 536.468 54.644 1.00 28.06 ? 961 TRP A C 1 ATOM 6916 O O . TRP A 1 907 ? 155.187 537.436 54.879 1.00 24.93 ? 961 TRP A O 1 ATOM 6917 C CB . TRP A 1 907 ? 155.474 534.067 55.175 1.00 28.90 ? 961 TRP A CB 1 ATOM 6918 C CG . TRP A 1 907 ? 153.980 534.058 55.256 1.00 31.34 ? 961 TRP A CG 1 ATOM 6919 C CD1 . TRP A 1 907 ? 153.228 533.490 56.238 1.00 34.80 ? 961 TRP A CD1 1 ATOM 6920 C CD2 . TRP A 1 907 ? 153.052 534.600 54.301 1.00 31.89 ? 961 TRP A CD2 1 ATOM 6921 N NE1 . TRP A 1 907 ? 151.893 533.663 55.971 1.00 35.12 ? 961 TRP A NE1 1 ATOM 6922 C CE2 . TRP A 1 907 ? 151.754 534.338 54.786 1.00 36.58 ? 961 TRP A CE2 1 ATOM 6923 C CE3 . TRP A 1 907 ? 153.188 535.314 53.094 1.00 33.50 ? 961 TRP A CE3 1 ATOM 6924 C CZ2 . TRP A 1 907 ? 150.596 534.757 54.109 1.00 35.99 ? 961 TRP A CZ2 1 ATOM 6925 C CZ3 . TRP A 1 907 ? 152.040 535.743 52.429 1.00 35.37 ? 961 TRP A CZ3 1 ATOM 6926 C CH2 . TRP A 1 907 ? 150.764 535.460 52.933 1.00 36.23 ? 961 TRP A CH2 1 ATOM 6927 N N . SER A 1 908 ? 156.555 536.303 53.493 1.00 23.93 ? 962 SER A N 1 ATOM 6928 C CA . SER A 1 908 ? 156.355 537.235 52.405 1.00 24.42 ? 962 SER A CA 1 ATOM 6929 C C . SER A 1 908 ? 156.320 536.511 51.094 1.00 30.05 ? 962 SER A C 1 ATOM 6930 O O . SER A 1 908 ? 156.997 535.493 50.914 1.00 30.41 ? 962 SER A O 1 ATOM 6931 C CB . SER A 1 908 ? 157.385 538.370 52.403 1.00 28.18 ? 962 SER A CB 1 ATOM 6932 O OG . SER A 1 908 ? 158.717 537.912 52.236 1.00 39.67 ? 962 SER A OG 1 ATOM 6933 N N . ILE A 1 909 ? 155.487 537.018 50.185 1.00 26.38 ? 963 ILE A N 1 ATOM 6934 C CA . ILE A 1 909 ? 155.366 536.519 48.823 1.00 26.20 ? 963 ILE A CA 1 ATOM 6935 C C . ILE A 1 909 ? 155.662 537.691 47.914 1.00 30.40 ? 963 ILE A C 1 ATOM 6936 O O . ILE A 1 909 ? 154.955 538.703 47.989 1.00 30.67 ? 963 ILE A O 1 ATOM 6937 C CB . ILE A 1 909 ? 153.980 535.888 48.513 1.00 28.99 ? 963 ILE A CB 1 ATOM 6938 C CG1 . ILE A 1 909 ? 153.747 534.640 49.361 1.00 29.25 ? 963 ILE A CG1 1 ATOM 6939 C CG2 . ILE A 1 909 ? 153.902 535.525 47.031 1.00 30.29 ? 963 ILE A CG2 1 ATOM 6940 C CD1 . ILE A 1 909 ? 152.359 534.036 49.277 1.00 39.47 ? 963 ILE A CD1 1 ATOM 6941 N N . HIS A 1 910 ? 156.709 537.554 47.080 1.00 26.54 ? 964 HIS A N 1 ATOM 6942 C CA A HIS A 1 910 ? 157.106 538.588 46.141 0.50 25.75 ? 964 HIS A CA 1 ATOM 6943 C CA B HIS A 1 910 ? 157.176 538.572 46.136 0.50 26.34 ? 964 HIS A CA 1 ATOM 6944 C C . HIS A 1 910 ? 156.760 538.190 44.713 1.00 31.17 ? 964 HIS A C 1 ATOM 6945 O O . HIS A 1 910 ? 157.029 537.053 44.295 1.00 33.17 ? 964 HIS A O 1 ATOM 6946 C CB A HIS A 1 910 ? 158.594 538.937 46.291 0.50 25.51 ? 964 HIS A CB 1 ATOM 6947 C CB B HIS A 1 910 ? 158.718 538.712 46.203 0.50 26.65 ? 964 HIS A CB 1 ATOM 6948 C CG A HIS A 1 910 ? 158.988 540.123 45.476 0.50 27.74 ? 964 HIS A CG 1 ATOM 6949 C CG B HIS A 1 910 ? 159.270 538.902 47.583 0.50 29.55 ? 964 HIS A CG 1 ATOM 6950 N ND1 A HIS A 1 910 ? 159.775 539.991 44.353 0.50 28.99 ? 964 HIS A ND1 1 ATOM 6951 N ND1 B HIS A 1 910 ? 159.642 537.822 48.366 0.50 31.11 ? 964 HIS A ND1 1 ATOM 6952 C CD2 A HIS A 1 910 ? 158.640 541.419 45.617 0.50 28.51 ? 964 HIS A CD2 1 ATOM 6953 C CD2 B HIS A 1 910 ? 159.502 540.044 48.275 0.50 31.11 ? 964 HIS A CD2 1 ATOM 6954 C CE1 A HIS A 1 910 ? 159.902 541.208 43.860 0.50 27.85 ? 964 HIS A CE1 1 ATOM 6955 C CE1 B HIS A 1 910 ? 160.073 538.337 49.509 0.50 30.40 ? 964 HIS A CE1 1 ATOM 6956 N NE2 A HIS A 1 910 ? 159.232 542.099 44.583 0.50 28.18 ? 964 HIS A NE2 1 ATOM 6957 N NE2 B HIS A 1 910 ? 160.006 539.669 49.505 0.50 30.64 ? 964 HIS A NE2 1 ATOM 6958 N N . LEU A 1 911 ? 156.131 539.115 43.975 1.00 26.83 ? 965 LEU A N 1 ATOM 6959 C CA . LEU A 1 911 ? 155.738 538.923 42.577 1.00 27.40 ? 965 LEU A CA 1 ATOM 6960 C C . LEU A 1 911 ? 156.795 539.619 41.704 1.00 32.40 ? 965 LEU A C 1 ATOM 6961 O O . LEU A 1 911 ? 156.912 540.838 41.748 1.00 31.14 ? 965 LEU A O 1 ATOM 6962 C CB . LEU A 1 911 ? 154.349 539.547 42.286 1.00 27.54 ? 965 LEU A CB 1 ATOM 6963 C CG . LEU A 1 911 ? 153.183 539.213 43.217 1.00 31.60 ? 965 LEU A CG 1 ATOM 6964 C CD1 . LEU A 1 911 ? 151.898 539.869 42.739 1.00 31.75 ? 965 LEU A CD1 1 ATOM 6965 C CD2 . LEU A 1 911 ? 152.987 537.706 43.324 1.00 31.45 ? 965 LEU A CD2 1 ATOM 6966 N N . ARG A 1 912 ? 157.586 538.856 40.947 1.00 32.61 ? 966 ARG A N 1 ATOM 6967 C CA . ARG A 1 912 ? 158.657 539.403 40.089 1.00 33.86 ? 966 ARG A CA 1 ATOM 6968 C C . ARG A 1 912 ? 158.185 539.621 38.648 1.00 40.06 ? 966 ARG A C 1 ATOM 6969 O O . ARG A 1 912 ? 157.513 538.746 38.120 1.00 41.11 ? 966 ARG A O 1 ATOM 6970 C CB . ARG A 1 912 ? 159.917 538.501 40.138 1.00 35.45 ? 966 ARG A CB 1 ATOM 6971 C CG . ARG A 1 912 ? 160.556 538.477 41.530 1.00 50.48 ? 966 ARG A CG 1 ATOM 6972 C CD . ARG A 1 912 ? 162.012 538.052 41.588 1.00 69.12 ? 966 ARG A CD 1 ATOM 6973 N NE . ARG A 1 912 ? 162.537 538.198 42.952 1.00 76.80 ? 966 ARG A NE 1 ATOM 6974 C CZ . ARG A 1 912 ? 163.278 537.292 43.593 1.00 91.10 ? 966 ARG A CZ 1 ATOM 6975 N NH1 . ARG A 1 912 ? 163.608 536.148 43.001 1.00 80.54 ? 966 ARG A NH1 1 ATOM 6976 N NH2 . ARG A 1 912 ? 163.692 537.524 44.832 1.00 72.49 ? 966 ARG A NH2 1 ATOM 6977 N N . ALA A 1 913 ? 158.495 540.758 37.999 1.00 36.86 ? 967 ALA A N 1 ATOM 6978 C CA . ALA A 1 913 ? 158.065 540.965 36.610 1.00 36.96 ? 967 ALA A CA 1 ATOM 6979 C C . ALA A 1 913 ? 159.032 540.316 35.603 1.00 43.26 ? 967 ALA A C 1 ATOM 6980 C CB . ALA A 1 913 ? 157.921 542.441 36.315 1.00 37.73 ? 967 ALA A CB 1 ATOM 6981 N N . PHE B 2 1 ? 170.317 506.714 29.410 1.00 53.07 ? 30 PHE B N 1 ATOM 6982 C CA . PHE B 2 1 ? 170.708 506.067 30.665 1.00 52.89 ? 30 PHE B CA 1 ATOM 6983 C C . PHE B 2 1 ? 169.475 505.731 31.565 1.00 54.18 ? 30 PHE B C 1 ATOM 6984 O O . PHE B 2 1 ? 168.949 504.626 31.440 1.00 54.57 ? 30 PHE B O 1 ATOM 6985 C CB . PHE B 2 1 ? 171.803 506.883 31.396 1.00 55.24 ? 30 PHE B CB 1 ATOM 6986 C CG . PHE B 2 1 ? 172.874 506.075 32.106 1.00 57.84 ? 30 PHE B CG 1 ATOM 6987 C CD1 . PHE B 2 1 ? 173.433 504.945 31.510 1.00 62.34 ? 30 PHE B CD1 1 ATOM 6988 C CD2 . PHE B 2 1 ? 173.385 506.493 33.331 1.00 60.80 ? 30 PHE B CD2 1 ATOM 6989 C CE1 . PHE B 2 1 ? 174.437 504.207 32.160 1.00 63.91 ? 30 PHE B CE1 1 ATOM 6990 C CE2 . PHE B 2 1 ? 174.394 505.760 33.979 1.00 64.36 ? 30 PHE B CE2 1 ATOM 6991 C CZ . PHE B 2 1 ? 174.913 504.620 33.390 1.00 62.95 ? 30 PHE B CZ 1 ATOM 6992 N N . TYR B 2 2 ? 169.002 506.652 32.433 1.00 48.48 ? 31 TYR B N 1 ATOM 6993 C CA . TYR B 2 2 ? 167.837 506.360 33.289 1.00 47.60 ? 31 TYR B CA 1 ATOM 6994 C C . TYR B 2 2 ? 166.535 506.934 32.728 1.00 52.31 ? 31 TYR B C 1 ATOM 6995 O O . TYR B 2 2 ? 166.414 508.149 32.548 1.00 52.41 ? 31 TYR B O 1 ATOM 6996 C CB . TYR B 2 2 ? 168.033 506.855 34.727 1.00 47.23 ? 31 TYR B CB 1 ATOM 6997 C CG . TYR B 2 2 ? 169.016 506.074 35.563 1.00 46.38 ? 31 TYR B CG 1 ATOM 6998 C CD1 . TYR B 2 2 ? 170.383 506.327 35.483 1.00 47.69 ? 31 TYR B CD1 1 ATOM 6999 C CD2 . TYR B 2 2 ? 168.576 505.172 36.528 1.00 46.55 ? 31 TYR B CD2 1 ATOM 7000 C CE1 . TYR B 2 2 ? 171.294 505.656 36.295 1.00 46.75 ? 31 TYR B CE1 1 ATOM 7001 C CE2 . TYR B 2 2 ? 169.478 504.509 37.364 1.00 46.93 ? 31 TYR B CE2 1 ATOM 7002 C CZ . TYR B 2 2 ? 170.839 504.766 37.251 1.00 49.10 ? 31 TYR B CZ 1 ATOM 7003 O OH . TYR B 2 2 ? 171.763 504.131 38.047 1.00 42.49 ? 31 TYR B OH 1 ATOM 7004 N N . GLU B 2 3 ? 165.559 506.059 32.470 1.00 49.07 ? 32 GLU B N 1 ATOM 7005 C CA . GLU B 2 3 ? 164.257 506.468 31.961 1.00 48.93 ? 32 GLU B CA 1 ATOM 7006 C C . GLU B 2 3 ? 163.348 506.990 33.089 1.00 51.83 ? 32 GLU B C 1 ATOM 7007 O O . GLU B 2 3 ? 163.139 506.291 34.078 1.00 51.73 ? 32 GLU B O 1 ATOM 7008 C CB . GLU B 2 3 ? 163.578 505.334 31.178 1.00 50.56 ? 32 GLU B CB 1 ATOM 7009 C CG . GLU B 2 3 ? 162.235 505.764 30.613 1.00 63.94 ? 32 GLU B CG 1 ATOM 7010 C CD . GLU B 2 3 ? 161.394 504.727 29.898 1.00 79.52 ? 32 GLU B CD 1 ATOM 7011 O OE1 . GLU B 2 3 ? 161.702 503.514 29.976 1.00 76.56 ? 32 GLU B OE1 1 ATOM 7012 O OE2 . GLU B 2 3 ? 160.395 505.144 29.272 1.00 66.97 ? 32 GLU B OE2 1 ATOM 7013 N N . GLU B 2 4 ? 162.775 508.203 32.908 1.00 47.22 ? 33 GLU B N 1 ATOM 7014 C CA . GLU B 2 4 ? 161.875 508.856 33.872 1.00 45.72 ? 33 GLU B CA 1 ATOM 7015 C C . GLU B 2 4 ? 160.450 508.320 33.761 1.00 47.46 ? 33 GLU B C 1 ATOM 7016 O O . GLU B 2 4 ? 159.985 507.963 32.671 1.00 48.22 ? 33 GLU B O 1 ATOM 7017 C CB . GLU B 2 4 ? 161.829 510.386 33.667 1.00 46.96 ? 33 GLU B CB 1 ATOM 7018 C CG . GLU B 2 4 ? 163.141 511.133 33.879 1.00 62.07 ? 33 GLU B CG 1 ATOM 7019 C CD . GLU B 2 4 ? 163.172 512.612 33.506 1.00 87.15 ? 33 GLU B CD 1 ATOM 7020 O OE1 . GLU B 2 4 ? 162.095 513.172 33.187 1.00 83.02 ? 33 GLU B OE1 1 ATOM 7021 O OE2 . GLU B 2 4 ? 164.275 513.214 33.542 1.00 67.54 ? 33 GLU B OE2 1 ATOM 7022 N N . SER B 2 5 ? 159.747 508.299 34.893 1.00 40.07 ? 34 SER B N 1 ATOM 7023 C CA . SER B 2 5 ? 158.338 507.939 34.960 1.00 37.61 ? 34 SER B CA 1 ATOM 7024 C C . SER B 2 5 ? 157.544 509.110 34.385 1.00 42.65 ? 34 SER B C 1 ATOM 7025 O O . SER B 2 5 ? 157.982 510.269 34.487 1.00 41.54 ? 34 SER B O 1 ATOM 7026 C CB . SER B 2 5 ? 157.915 507.695 36.405 1.00 35.96 ? 34 SER B CB 1 ATOM 7027 O OG . SER B 2 5 ? 158.279 508.758 37.270 1.00 24.98 ? 34 SER B OG 1 ATOM 7028 N N . LYS B 2 6 ? 156.393 508.802 33.771 1.00 40.50 ? 35 LYS B N 1 ATOM 7029 C CA . LYS B 2 6 ? 155.525 509.795 33.154 1.00 40.95 ? 35 LYS B CA 1 ATOM 7030 C C . LYS B 2 6 ? 154.685 510.498 34.199 1.00 44.54 ? 35 LYS B C 1 ATOM 7031 O O . LYS B 2 6 ? 154.403 509.917 35.249 1.00 45.55 ? 35 LYS B O 1 ATOM 7032 C CB . LYS B 2 6 ? 154.638 509.161 32.072 1.00 43.96 ? 35 LYS B CB 1 ATOM 7033 C CG . LYS B 2 6 ? 155.434 508.782 30.831 1.00 61.94 ? 35 LYS B CG 1 ATOM 7034 C CD . LYS B 2 6 ? 154.530 508.412 29.666 1.00 76.80 ? 35 LYS B CD 1 ATOM 7035 C CE . LYS B 2 6 ? 155.284 508.475 28.358 1.00 88.91 ? 35 LYS B CE 1 ATOM 7036 N NZ . LYS B 2 6 ? 154.374 508.413 27.180 1.00 95.40 ? 35 LYS B NZ 1 ATOM 7037 N N . PRO B 2 7 ? 154.287 511.756 33.935 1.00 38.66 ? 36 PRO B N 1 ATOM 7038 C CA . PRO B 2 7 ? 153.483 512.491 34.925 1.00 36.97 ? 36 PRO B CA 1 ATOM 7039 C C . PRO B 2 7 ? 152.042 512.014 34.997 1.00 35.37 ? 36 PRO B C 1 ATOM 7040 O O . PRO B 2 7 ? 151.644 511.133 34.247 1.00 34.14 ? 36 PRO B O 1 ATOM 7041 C CB . PRO B 2 7 ? 153.585 513.942 34.454 1.00 38.95 ? 36 PRO B CB 1 ATOM 7042 C CG . PRO B 2 7 ? 153.822 513.845 32.989 1.00 44.23 ? 36 PRO B CG 1 ATOM 7043 C CD . PRO B 2 7 ? 154.602 512.589 32.755 1.00 39.96 ? 36 PRO B CD 1 ATOM 7044 N N . PHE B 2 8 ? 151.271 512.590 35.909 1.00 29.86 ? 37 PHE B N 1 ATOM 7045 C CA . PHE B 2 8 ? 149.871 512.245 36.090 1.00 29.82 ? 37 PHE B CA 1 ATOM 7046 C C . PHE B 2 8 ? 148.976 513.122 35.243 1.00 36.80 ? 37 PHE B C 1 ATOM 7047 O O . PHE B 2 8 ? 149.092 514.356 35.300 1.00 34.04 ? 37 PHE B O 1 ATOM 7048 C CB . PHE B 2 8 ? 149.471 512.430 37.559 1.00 31.32 ? 37 PHE B CB 1 ATOM 7049 C CG . PHE B 2 8 ? 148.006 512.184 37.837 1.00 33.18 ? 37 PHE B CG 1 ATOM 7050 C CD1 . PHE B 2 8 ? 147.497 510.893 37.873 1.00 37.02 ? 37 PHE B CD1 1 ATOM 7051 C CD2 . PHE B 2 8 ? 147.142 513.242 38.086 1.00 35.00 ? 37 PHE B CD2 1 ATOM 7052 C CE1 . PHE B 2 8 ? 146.153 510.664 38.146 1.00 37.99 ? 37 PHE B CE1 1 ATOM 7053 C CE2 . PHE B 2 8 ? 145.791 513.013 38.344 1.00 37.45 ? 37 PHE B CE2 1 ATOM 7054 C CZ . PHE B 2 8 ? 145.309 511.725 38.386 1.00 36.10 ? 37 PHE B CZ 1 ATOM 7055 N N . THR B 2 9 ? 148.025 512.500 34.521 1.00 36.37 ? 38 THR B N 1 ATOM 7056 C CA . THR B 2 9 ? 147.037 513.293 33.790 1.00 37.22 ? 38 THR B CA 1 ATOM 7057 C C . THR B 2 9 ? 145.736 513.129 34.509 1.00 41.90 ? 38 THR B C 1 ATOM 7058 O O . THR B 2 9 ? 145.338 511.995 34.813 1.00 41.28 ? 38 THR B O 1 ATOM 7059 C CB . THR B 2 9 ? 146.932 512.956 32.286 1.00 46.50 ? 38 THR B CB 1 ATOM 7060 O OG1 . THR B 2 9 ? 148.224 513.115 31.692 1.00 47.83 ? 38 THR B OG1 1 ATOM 7061 C CG2 . THR B 2 9 ? 145.943 513.881 31.552 1.00 42.54 ? 38 THR B CG2 1 ATOM 7062 N N . CYS B 2 10 ? 145.085 514.274 34.814 1.00 38.94 ? 39 CYS B N 1 ATOM 7063 C CA . CYS B 2 10 ? 143.750 514.341 35.425 1.00 38.53 ? 39 CYS B CA 1 ATOM 7064 C C . CYS B 2 10 ? 142.858 513.487 34.556 1.00 43.80 ? 39 CYS B C 1 ATOM 7065 O O . CYS B 2 10 ? 143.091 513.435 33.351 1.00 43.06 ? 39 CYS B O 1 ATOM 7066 C CB . CYS B 2 10 ? 143.230 515.781 35.457 1.00 38.03 ? 39 CYS B CB 1 ATOM 7067 S SG . CYS B 2 10 ? 144.319 516.966 36.292 1.00 41.53 ? 39 CYS B SG 1 ATOM 7068 N N . LEU B 2 11 ? 141.832 512.845 35.130 1.00 42.46 ? 40 LEU B N 1 ATOM 7069 C CA . LEU B 2 11 ? 140.868 512.071 34.337 1.00 43.55 ? 40 LEU B CA 1 ATOM 7070 C C . LEU B 2 11 ? 140.083 512.955 33.329 1.00 48.86 ? 40 LEU B C 1 ATOM 7071 O O . LEU B 2 11 ? 139.615 512.429 32.322 1.00 48.03 ? 40 LEU B O 1 ATOM 7072 C CB . LEU B 2 11 ? 139.874 511.310 35.220 1.00 44.01 ? 40 LEU B CB 1 ATOM 7073 C CG . LEU B 2 11 ? 140.403 510.377 36.304 1.00 49.79 ? 40 LEU B CG 1 ATOM 7074 C CD1 . LEU B 2 11 ? 139.270 509.544 36.882 1.00 50.75 ? 40 LEU B CD1 1 ATOM 7075 C CD2 . LEU B 2 11 ? 141.513 509.483 35.796 1.00 52.05 ? 40 LEU B CD2 1 ATOM 7076 N N . ASP B 2 12 ? 139.945 514.282 33.592 1.00 46.40 ? 41 ASP B N 1 ATOM 7077 C CA . ASP B 2 12 ? 139.246 515.205 32.684 1.00 47.28 ? 41 ASP B CA 1 ATOM 7078 C C . ASP B 2 12 ? 140.175 515.858 31.641 1.00 53.25 ? 41 ASP B C 1 ATOM 7079 O O . ASP B 2 12 ? 139.738 516.760 30.912 1.00 53.28 ? 41 ASP B O 1 ATOM 7080 C CB . ASP B 2 12 ? 138.482 516.293 33.471 1.00 49.15 ? 41 ASP B CB 1 ATOM 7081 C CG . ASP B 2 12 ? 139.338 517.192 34.350 1.00 62.10 ? 41 ASP B CG 1 ATOM 7082 O OD1 . ASP B 2 12 ? 140.594 517.061 34.313 1.00 63.80 ? 41 ASP B OD1 1 ATOM 7083 O OD2 . ASP B 2 12 ? 138.760 518.012 35.096 1.00 67.60 ? 41 ASP B OD2 1 ATOM 7084 N N . GLY B 2 13 ? 141.446 515.447 31.624 1.00 50.60 ? 42 GLY B N 1 ATOM 7085 C CA . GLY B 2 13 ? 142.468 515.982 30.727 1.00 50.70 ? 42 GLY B CA 1 ATOM 7086 C C . GLY B 2 13 ? 142.838 517.447 30.910 1.00 55.26 ? 42 GLY B C 1 ATOM 7087 O O . GLY B 2 13 ? 143.656 517.949 30.140 1.00 56.27 ? 42 GLY B O 1 ATOM 7088 N N . THR B 2 14 ? 142.282 518.152 31.924 1.00 51.02 ? 43 THR B N 1 ATOM 7089 C CA . THR B 2 14 ? 142.547 519.592 32.128 1.00 50.99 ? 43 THR B CA 1 ATOM 7090 C C . THR B 2 14 ? 144.013 519.956 32.397 1.00 55.39 ? 43 THR B C 1 ATOM 7091 O O . THR B 2 14 ? 144.410 521.086 32.106 1.00 56.08 ? 43 THR B O 1 ATOM 7092 C CB . THR B 2 14 ? 141.648 520.230 33.211 1.00 59.46 ? 43 THR B CB 1 ATOM 7093 O OG1 . THR B 2 14 ? 141.888 519.651 34.514 1.00 54.88 ? 43 THR B OG1 1 ATOM 7094 C CG2 . THR B 2 14 ? 140.168 520.194 32.835 1.00 56.25 ? 43 THR B CG2 1 ATOM 7095 N N . ALA B 2 15 ? 144.804 519.027 32.960 1.00 50.95 ? 44 ALA B N 1 ATOM 7096 C CA . ALA B 2 15 ? 146.211 519.280 33.272 1.00 49.70 ? 44 ALA B CA 1 ATOM 7097 C C . ALA B 2 15 ? 147.046 518.003 33.407 1.00 51.49 ? 44 ALA B C 1 ATOM 7098 O O . ALA B 2 15 ? 146.551 516.874 33.300 1.00 49.24 ? 44 ALA B O 1 ATOM 7099 C CB . ALA B 2 15 ? 146.338 520.134 34.537 1.00 49.88 ? 44 ALA B CB 1 ATOM 7100 N N . THR B 2 16 ? 148.337 518.217 33.619 1.00 47.66 ? 45 THR B N 1 ATOM 7101 C CA . THR B 2 16 ? 149.317 517.171 33.800 1.00 46.92 ? 45 THR B CA 1 ATOM 7102 C C . THR B 2 16 ? 150.211 517.661 34.883 1.00 47.50 ? 45 THR B C 1 ATOM 7103 O O . THR B 2 16 ? 150.719 518.791 34.832 1.00 48.42 ? 45 THR B O 1 ATOM 7104 C CB . THR B 2 16 ? 150.040 516.841 32.488 1.00 60.64 ? 45 THR B CB 1 ATOM 7105 O OG1 . THR B 2 16 ? 149.090 516.325 31.550 1.00 63.89 ? 45 THR B OG1 1 ATOM 7106 C CG2 . THR B 2 16 ? 151.110 515.814 32.677 1.00 58.68 ? 45 THR B CG2 1 ATOM 7107 N N . ILE B 2 17 ? 150.381 516.843 35.892 1.00 40.15 ? 46 ILE B N 1 ATOM 7108 C CA . ILE B 2 17 ? 151.135 517.281 37.042 1.00 38.26 ? 46 ILE B CA 1 ATOM 7109 C C . ILE B 2 17 ? 152.111 516.217 37.459 1.00 39.29 ? 46 ILE B C 1 ATOM 7110 O O . ILE B 2 17 ? 151.861 515.036 37.241 1.00 39.31 ? 46 ILE B O 1 ATOM 7111 C CB . ILE B 2 17 ? 150.106 517.609 38.172 1.00 41.09 ? 46 ILE B CB 1 ATOM 7112 C CG1 . ILE B 2 17 ? 149.260 516.356 38.552 1.00 40.94 ? 46 ILE B CG1 1 ATOM 7113 C CG2 . ILE B 2 17 ? 149.192 518.775 37.746 1.00 41.30 ? 46 ILE B CG2 1 ATOM 7114 C CD1 . ILE B 2 17 ? 148.306 516.516 39.661 1.00 39.23 ? 46 ILE B CD1 1 ATOM 7115 N N . PRO B 2 18 ? 153.204 516.578 38.128 1.00 33.75 ? 47 PRO B N 1 ATOM 7116 C CA . PRO B 2 18 ? 154.057 515.532 38.698 1.00 33.02 ? 47 PRO B CA 1 ATOM 7117 C C . PRO B 2 18 ? 153.285 514.692 39.739 1.00 36.99 ? 47 PRO B C 1 ATOM 7118 O O . PRO B 2 18 ? 152.210 515.084 40.199 1.00 37.29 ? 47 PRO B O 1 ATOM 7119 C CB . PRO B 2 18 ? 155.186 516.325 39.357 1.00 34.36 ? 47 PRO B CB 1 ATOM 7120 C CG . PRO B 2 18 ? 154.600 517.666 39.633 1.00 38.86 ? 47 PRO B CG 1 ATOM 7121 C CD . PRO B 2 18 ? 153.679 517.930 38.494 1.00 34.80 ? 47 PRO B CD 1 ATOM 7122 N N . PHE B 2 19 ? 153.841 513.549 40.112 1.00 33.20 ? 48 PHE B N 1 ATOM 7123 C CA . PHE B 2 19 ? 153.208 512.660 41.065 1.00 32.96 ? 48 PHE B CA 1 ATOM 7124 C C . PHE B 2 19 ? 153.292 513.187 42.506 1.00 37.05 ? 48 PHE B C 1 ATOM 7125 O O . PHE B 2 19 ? 152.468 512.790 43.342 1.00 34.55 ? 48 PHE B O 1 ATOM 7126 C CB . PHE B 2 19 ? 153.717 511.220 40.917 1.00 35.04 ? 48 PHE B CB 1 ATOM 7127 C CG . PHE B 2 19 ? 152.953 510.446 39.862 1.00 36.69 ? 48 PHE B CG 1 ATOM 7128 C CD1 . PHE B 2 19 ? 151.591 510.193 40.012 1.00 39.15 ? 48 PHE B CD1 1 ATOM 7129 C CD2 . PHE B 2 19 ? 153.596 509.963 38.724 1.00 39.26 ? 48 PHE B CD2 1 ATOM 7130 C CE1 . PHE B 2 19 ? 150.876 509.499 39.029 1.00 40.02 ? 48 PHE B CE1 1 ATOM 7131 C CE2 . PHE B 2 19 ? 152.877 509.268 37.741 1.00 41.82 ? 48 PHE B CE2 1 ATOM 7132 C CZ . PHE B 2 19 ? 151.518 509.051 37.896 1.00 39.50 ? 48 PHE B CZ 1 ATOM 7133 N N . ASP B 2 20 ? 154.204 514.153 42.786 1.00 34.72 ? 49 ASP B N 1 ATOM 7134 C CA . ASP B 2 20 ? 154.206 514.779 44.110 1.00 33.91 ? 49 ASP B CA 1 ATOM 7135 C C . ASP B 2 20 ? 153.029 515.796 44.259 1.00 35.09 ? 49 ASP B C 1 ATOM 7136 O O . ASP B 2 20 ? 152.879 516.391 45.323 1.00 34.49 ? 49 ASP B O 1 ATOM 7137 C CB . ASP B 2 20 ? 155.578 515.367 44.508 1.00 36.69 ? 49 ASP B CB 1 ATOM 7138 C CG . ASP B 2 20 ? 156.189 516.348 43.533 1.00 54.40 ? 49 ASP B CG 1 ATOM 7139 O OD1 . ASP B 2 20 ? 155.460 517.265 43.069 1.00 55.65 ? 49 ASP B OD1 1 ATOM 7140 O OD2 . ASP B 2 20 ? 157.407 516.235 43.267 1.00 59.98 ? 49 ASP B OD2 1 ATOM 7141 N N . GLN B 2 21 ? 152.187 515.967 43.196 1.00 29.37 ? 50 GLN B N 1 ATOM 7142 C CA . GLN B 2 21 ? 150.967 516.778 43.233 1.00 28.01 ? 50 GLN B CA 1 ATOM 7143 C C . GLN B 2 21 ? 149.707 515.910 43.346 1.00 30.36 ? 50 GLN B C 1 ATOM 7144 O O . GLN B 2 21 ? 148.589 516.430 43.323 1.00 27.72 ? 50 GLN B O 1 ATOM 7145 C CB . GLN B 2 21 ? 150.881 517.727 42.050 1.00 29.09 ? 50 GLN B CB 1 ATOM 7146 C CG . GLN B 2 21 ? 151.877 518.830 42.186 1.00 27.47 ? 50 GLN B CG 1 ATOM 7147 C CD . GLN B 2 21 ? 151.708 519.944 41.224 1.00 44.72 ? 50 GLN B CD 1 ATOM 7148 O OE1 . GLN B 2 21 ? 150.725 520.053 40.494 1.00 45.47 ? 50 GLN B OE1 1 ATOM 7149 N NE2 . GLN B 2 21 ? 152.661 520.849 41.257 1.00 46.04 ? 50 GLN B NE2 1 ATOM 7150 N N . VAL B 2 22 ? 149.898 514.583 43.476 1.00 27.35 ? 51 VAL B N 1 ATOM 7151 C CA . VAL B 2 22 ? 148.830 513.620 43.706 1.00 26.41 ? 51 VAL B CA 1 ATOM 7152 C C . VAL B 2 22 ? 148.751 513.425 45.208 1.00 31.96 ? 51 VAL B C 1 ATOM 7153 O O . VAL B 2 22 ? 149.762 513.104 45.839 1.00 33.03 ? 51 VAL B O 1 ATOM 7154 C CB . VAL B 2 22 ? 149.102 512.296 42.982 1.00 28.23 ? 51 VAL B CB 1 ATOM 7155 C CG1 . VAL B 2 22 ? 148.087 511.235 43.377 1.00 27.41 ? 51 VAL B CG1 1 ATOM 7156 C CG2 . VAL B 2 22 ? 149.127 512.512 41.473 1.00 27.61 ? 51 VAL B CG2 1 ATOM 7157 N N . ASN B 2 23 ? 147.562 513.630 45.791 1.00 27.79 ? 52 ASN B N 1 ATOM 7158 C CA . ASN B 2 23 ? 147.369 513.511 47.241 1.00 27.59 ? 52 ASN B CA 1 ATOM 7159 C C . ASN B 2 23 ? 148.357 514.394 48.007 1.00 30.90 ? 52 ASN B C 1 ATOM 7160 O O . ASN B 2 23 ? 148.904 514.005 49.030 1.00 29.87 ? 52 ASN B O 1 ATOM 7161 C CB . ASN B 2 23 ? 147.376 512.053 47.718 1.00 27.20 ? 52 ASN B CB 1 ATOM 7162 C CG . ASN B 2 23 ? 146.083 511.335 47.418 1.00 35.13 ? 52 ASN B CG 1 ATOM 7163 O OD1 . ASN B 2 23 ? 145.054 511.956 47.155 1.00 17.48 ? 52 ASN B OD1 1 ATOM 7164 N ND2 . ASN B 2 23 ? 146.099 510.006 47.483 1.00 24.83 ? 52 ASN B ND2 1 ATOM 7165 N N . ASP B 2 24 ? 148.552 515.606 47.506 1.00 27.22 ? 53 ASP B N 1 ATOM 7166 C CA . ASP B 2 24 ? 149.446 516.568 48.126 1.00 26.61 ? 53 ASP B CA 1 ATOM 7167 C C . ASP B 2 24 ? 148.675 517.623 48.916 1.00 30.80 ? 53 ASP B C 1 ATOM 7168 O O . ASP B 2 24 ? 149.256 518.616 49.353 1.00 32.36 ? 53 ASP B O 1 ATOM 7169 C CB . ASP B 2 24 ? 150.364 517.200 47.074 1.00 27.42 ? 53 ASP B CB 1 ATOM 7170 C CG . ASP B 2 24 ? 149.797 518.364 46.292 1.00 26.95 ? 53 ASP B CG 1 ATOM 7171 O OD1 . ASP B 2 24 ? 148.664 518.239 45.747 1.00 23.20 ? 53 ASP B OD1 1 ATOM 7172 O OD2 . ASP B 2 24 ? 150.503 519.369 46.169 1.00 31.88 ? 53 ASP B OD2 1 ATOM 7173 N N . ASP B 2 25 ? 147.370 517.395 49.124 1.00 25.00 ? 54 ASP B N 1 ATOM 7174 C CA . ASP B 2 25 ? 146.528 518.279 49.926 1.00 22.43 ? 54 ASP B CA 1 ATOM 7175 C C . ASP B 2 25 ? 146.308 519.674 49.283 1.00 26.53 ? 54 ASP B C 1 ATOM 7176 O O . ASP B 2 25 ? 146.096 520.675 49.974 1.00 26.93 ? 54 ASP B O 1 ATOM 7177 C CB . ASP B 2 25 ? 147.067 518.382 51.366 1.00 21.48 ? 54 ASP B CB 1 ATOM 7178 C CG . ASP B 2 25 ? 145.979 518.611 52.378 1.00 27.13 ? 54 ASP B CG 1 ATOM 7179 O OD1 . ASP B 2 25 ? 144.785 518.463 52.016 1.00 26.55 ? 54 ASP B OD1 1 ATOM 7180 O OD2 . ASP B 2 25 ? 146.312 518.920 53.538 1.00 36.03 ? 54 ASP B OD2 1 ATOM 7181 N N . TYR B 2 26 ? 146.349 519.715 47.958 1.00 20.92 ? 55 TYR B N 1 ATOM 7182 C CA . TYR B 2 26 ? 146.027 520.887 47.161 1.00 19.77 ? 55 TYR B CA 1 ATOM 7183 C C . TYR B 2 26 ? 145.340 520.379 45.896 1.00 23.47 ? 55 TYR B C 1 ATOM 7184 O O . TYR B 2 26 ? 145.821 519.466 45.247 1.00 23.84 ? 55 TYR B O 1 ATOM 7185 C CB . TYR B 2 26 ? 147.242 521.773 46.825 1.00 20.47 ? 55 TYR B CB 1 ATOM 7186 C CG . TYR B 2 26 ? 146.817 523.029 46.113 1.00 21.85 ? 55 TYR B CG 1 ATOM 7187 C CD1 . TYR B 2 26 ? 146.689 523.058 44.728 1.00 23.62 ? 55 TYR B CD1 1 ATOM 7188 C CD2 . TYR B 2 26 ? 146.463 524.168 46.825 1.00 23.22 ? 55 TYR B CD2 1 ATOM 7189 C CE1 . TYR B 2 26 ? 146.220 524.195 44.071 1.00 25.37 ? 55 TYR B CE1 1 ATOM 7190 C CE2 . TYR B 2 26 ? 146.008 525.315 46.179 1.00 24.69 ? 55 TYR B CE2 1 ATOM 7191 C CZ . TYR B 2 26 ? 145.904 525.330 44.802 1.00 29.00 ? 55 TYR B CZ 1 ATOM 7192 O OH . TYR B 2 26 ? 145.425 526.465 44.214 1.00 26.30 ? 55 TYR B OH 1 ATOM 7193 N N . CYS B 2 27 ? 144.223 520.966 45.551 1.00 19.54 ? 56 CYS B N 1 ATOM 7194 C CA . CYS B 2 27 ? 143.461 520.601 44.377 1.00 19.48 ? 56 CYS B CA 1 ATOM 7195 C C . CYS B 2 27 ? 144.015 521.147 43.061 1.00 24.85 ? 56 CYS B C 1 ATOM 7196 O O . CYS B 2 27 ? 143.928 522.356 42.794 1.00 24.70 ? 56 CYS B O 1 ATOM 7197 C CB . CYS B 2 27 ? 142.014 521.010 44.560 1.00 20.34 ? 56 CYS B CB 1 ATOM 7198 S SG . CYS B 2 27 ? 140.897 520.181 43.428 1.00 25.18 ? 56 CYS B SG 1 ATOM 7199 N N . ASP B 2 28 ? 144.503 520.241 42.204 1.00 22.27 ? 57 ASP B N 1 ATOM 7200 C CA . ASP B 2 28 ? 145.105 520.610 40.926 1.00 22.70 ? 57 ASP B CA 1 ATOM 7201 C C . ASP B 2 28 ? 144.264 520.274 39.725 1.00 31.26 ? 57 ASP B C 1 ATOM 7202 O O . ASP B 2 28 ? 144.471 520.867 38.674 1.00 29.78 ? 57 ASP B O 1 ATOM 7203 C CB . ASP B 2 28 ? 146.508 520.022 40.795 1.00 22.43 ? 57 ASP B CB 1 ATOM 7204 C CG . ASP B 2 28 ? 147.438 520.584 41.844 1.00 25.59 ? 57 ASP B CG 1 ATOM 7205 O OD1 . ASP B 2 28 ? 147.716 521.806 41.794 1.00 24.60 ? 57 ASP B OD1 1 ATOM 7206 O OD2 . ASP B 2 28 ? 147.820 519.825 42.773 1.00 25.78 ? 57 ASP B OD2 1 ATOM 7207 N N . CYS B 2 29 ? 143.319 519.345 39.871 1.00 33.69 ? 58 CYS B N 1 ATOM 7208 C CA . CYS B 2 29 ? 142.434 518.934 38.780 1.00 35.34 ? 58 CYS B CA 1 ATOM 7209 C C . CYS B 2 29 ? 141.036 519.469 38.986 1.00 37.49 ? 58 CYS B C 1 ATOM 7210 O O . CYS B 2 29 ? 140.490 519.367 40.096 1.00 36.66 ? 58 CYS B O 1 ATOM 7211 C CB . CYS B 2 29 ? 142.412 517.417 38.622 1.00 36.29 ? 58 CYS B CB 1 ATOM 7212 S SG . CYS B 2 29 ? 144.022 516.688 38.296 1.00 40.71 ? 58 CYS B SG 1 ATOM 7213 N N . LYS B 2 30 ? 140.430 519.966 37.904 1.00 32.51 ? 59 LYS B N 1 ATOM 7214 C CA . LYS B 2 30 ? 139.058 520.463 37.955 1.00 32.78 ? 59 LYS B CA 1 ATOM 7215 C C . LYS B 2 30 ? 138.055 519.377 38.342 1.00 38.58 ? 59 LYS B C 1 ATOM 7216 O O . LYS B 2 30 ? 137.053 519.713 38.955 1.00 39.75 ? 59 LYS B O 1 ATOM 7217 C CB . LYS B 2 30 ? 138.668 521.179 36.660 1.00 34.99 ? 59 LYS B CB 1 ATOM 7218 C CG . LYS B 2 30 ? 139.168 522.615 36.660 1.00 54.22 ? 59 LYS B CG 1 ATOM 7219 C CD . LYS B 2 30 ? 139.791 523.013 35.335 1.00 70.31 ? 59 LYS B CD 1 ATOM 7220 C CE . LYS B 2 30 ? 140.806 524.118 35.485 1.00 80.61 ? 59 LYS B CE 1 ATOM 7221 N NZ . LYS B 2 30 ? 141.639 524.263 34.261 1.00 88.42 ? 59 LYS B NZ 1 ATOM 7222 N N . ASP B 2 31 ? 138.344 518.085 38.034 1.00 34.15 ? 60 ASP B N 1 ATOM 7223 C CA . ASP B 2 31 ? 137.502 516.931 38.399 1.00 32.99 ? 60 ASP B CA 1 ATOM 7224 C C . ASP B 2 31 ? 137.806 516.354 39.796 1.00 35.03 ? 60 ASP B C 1 ATOM 7225 O O . ASP B 2 31 ? 137.116 515.434 40.238 1.00 35.16 ? 60 ASP B O 1 ATOM 7226 C CB . ASP B 2 31 ? 137.603 515.800 37.351 1.00 34.56 ? 60 ASP B CB 1 ATOM 7227 C CG . ASP B 2 31 ? 138.956 515.109 37.154 1.00 38.56 ? 60 ASP B CG 1 ATOM 7228 O OD1 . ASP B 2 31 ? 139.942 515.494 37.816 1.00 38.70 ? 60 ASP B OD1 1 ATOM 7229 O OD2 . ASP B 2 31 ? 139.038 514.233 36.300 1.00 43.61 ? 60 ASP B OD2 1 ATOM 7230 N N . GLY B 2 32 ? 138.843 516.869 40.447 1.00 29.70 ? 61 GLY B N 1 ATOM 7231 C CA . GLY B 2 32 ? 139.275 516.405 41.757 1.00 28.86 ? 61 GLY B CA 1 ATOM 7232 C C . GLY B 2 32 ? 140.058 515.101 41.783 1.00 31.00 ? 61 GLY B C 1 ATOM 7233 O O . GLY B 2 32 ? 140.311 514.560 42.869 1.00 29.13 ? 61 GLY B O 1 ATOM 7234 N N . SER B 2 33 ? 140.471 514.594 40.604 1.00 26.66 ? 62 SER B N 1 ATOM 7235 C CA . SER B 2 33 ? 141.109 513.283 40.499 1.00 25.04 ? 62 SER B CA 1 ATOM 7236 C C . SER B 2 33 ? 142.535 513.226 41.023 1.00 29.10 ? 62 SER B C 1 ATOM 7237 O O . SER B 2 33 ? 143.059 512.123 41.228 1.00 28.23 ? 62 SER B O 1 ATOM 7238 C CB . SER B 2 33 ? 141.029 512.727 39.085 1.00 24.03 ? 62 SER B CB 1 ATOM 7239 O OG . SER B 2 33 ? 141.688 513.552 38.152 1.00 29.23 ? 62 SER B OG 1 ATOM 7240 N N . ASP B 2 34 ? 143.155 514.371 41.310 1.00 23.35 ? 63 ASP B N 1 ATOM 7241 C CA . ASP B 2 34 ? 144.500 514.307 41.879 1.00 21.50 ? 63 ASP B CA 1 ATOM 7242 C C . ASP B 2 34 ? 144.442 514.120 43.393 1.00 24.33 ? 63 ASP B C 1 ATOM 7243 O O . ASP B 2 34 ? 145.458 513.823 43.993 1.00 22.60 ? 63 ASP B O 1 ATOM 7244 C CB . ASP B 2 34 ? 145.321 515.558 41.536 1.00 23.01 ? 63 ASP B CB 1 ATOM 7245 C CG . ASP B 2 34 ? 144.776 516.874 42.090 1.00 23.19 ? 63 ASP B CG 1 ATOM 7246 O OD1 . ASP B 2 34 ? 143.606 517.197 41.804 1.00 20.05 ? 63 ASP B OD1 1 ATOM 7247 O OD2 . ASP B 2 34 ? 145.549 517.606 42.756 1.00 25.45 ? 63 ASP B OD2 1 ATOM 7248 N N . GLU B 2 35 ? 143.266 514.279 44.013 1.00 22.03 ? 64 GLU B N 1 ATOM 7249 C CA . GLU B 2 35 ? 143.151 514.193 45.460 1.00 22.53 ? 64 GLU B CA 1 ATOM 7250 C C . GLU B 2 35 ? 142.112 513.150 45.962 1.00 27.28 ? 64 GLU B C 1 ATOM 7251 O O . GLU B 2 35 ? 141.275 513.476 46.832 1.00 27.30 ? 64 GLU B O 1 ATOM 7252 C CB . GLU B 2 35 ? 142.871 515.599 46.028 1.00 23.40 ? 64 GLU B CB 1 ATOM 7253 C CG . GLU B 2 35 ? 143.922 516.647 45.718 1.00 18.49 ? 64 GLU B CG 1 ATOM 7254 C CD . GLU B 2 35 ? 145.224 516.403 46.433 1.00 34.47 ? 64 GLU B CD 1 ATOM 7255 O OE1 . GLU B 2 35 ? 145.187 516.036 47.626 1.00 23.88 ? 64 GLU B OE1 1 ATOM 7256 O OE2 . GLU B 2 35 ? 146.290 516.590 45.807 1.00 26.58 ? 64 GLU B OE2 1 ATOM 7257 N N . PRO B 2 36 ? 142.207 511.864 45.504 1.00 24.86 ? 65 PRO B N 1 ATOM 7258 C CA . PRO B 2 36 ? 141.256 510.853 45.989 1.00 24.94 ? 65 PRO B CA 1 ATOM 7259 C C . PRO B 2 36 ? 141.395 510.530 47.478 1.00 30.03 ? 65 PRO B C 1 ATOM 7260 O O . PRO B 2 36 ? 140.429 510.062 48.082 1.00 30.66 ? 65 PRO B O 1 ATOM 7261 C CB . PRO B 2 36 ? 141.584 509.632 45.131 1.00 26.10 ? 65 PRO B CB 1 ATOM 7262 C CG . PRO B 2 36 ? 143.032 509.776 44.821 1.00 30.33 ? 65 PRO B CG 1 ATOM 7263 C CD . PRO B 2 36 ? 143.162 511.245 44.551 1.00 26.48 ? 65 PRO B CD 1 ATOM 7264 N N . GLY B 2 37 ? 142.560 510.810 48.055 1.00 25.03 ? 66 GLY B N 1 ATOM 7265 C CA . GLY B 2 37 ? 142.850 510.505 49.451 1.00 24.07 ? 66 GLY B CA 1 ATOM 7266 C C . GLY B 2 37 ? 142.778 511.648 50.437 1.00 27.31 ? 66 GLY B C 1 ATOM 7267 O O . GLY B 2 37 ? 143.028 511.450 51.631 1.00 27.31 ? 66 GLY B O 1 ATOM 7268 N N . THR B 2 38 ? 142.457 512.853 49.958 1.00 23.47 ? 67 THR B N 1 ATOM 7269 C CA . THR B 2 38 ? 142.415 514.012 50.827 1.00 23.27 ? 67 THR B CA 1 ATOM 7270 C C . THR B 2 38 ? 141.098 514.783 50.751 1.00 28.69 ? 67 THR B C 1 ATOM 7271 O O . THR B 2 38 ? 140.191 514.429 50.000 1.00 27.21 ? 67 THR B O 1 ATOM 7272 C CB . THR B 2 38 ? 143.586 514.960 50.525 1.00 26.56 ? 67 THR B CB 1 ATOM 7273 O OG1 . THR B 2 38 ? 143.276 515.668 49.343 1.00 29.40 ? 67 THR B OG1 1 ATOM 7274 C CG2 . THR B 2 38 ? 144.940 514.258 50.426 1.00 22.92 ? 67 THR B CG2 1 ATOM 7275 N N . ALA B 2 39 ? 141.022 515.876 51.528 1.00 27.31 ? 68 ALA B N 1 ATOM 7276 C CA . ALA B 2 39 ? 139.869 516.781 51.552 1.00 27.55 ? 68 ALA B CA 1 ATOM 7277 C C . ALA B 2 39 ? 140.095 518.036 50.697 1.00 32.23 ? 68 ALA B C 1 ATOM 7278 O O . ALA B 2 39 ? 139.347 519.010 50.838 1.00 32.76 ? 68 ALA B O 1 ATOM 7279 C CB . ALA B 2 39 ? 139.604 517.205 52.987 1.00 27.80 ? 68 ALA B CB 1 ATOM 7280 N N . ALA B 2 40 ? 141.113 518.032 49.831 1.00 27.21 ? 69 ALA B N 1 ATOM 7281 C CA . ALA B 2 40 ? 141.515 519.242 49.124 1.00 26.21 ? 69 ALA B CA 1 ATOM 7282 C C . ALA B 2 40 ? 140.634 519.685 47.972 1.00 26.37 ? 69 ALA B C 1 ATOM 7283 O O . ALA B 2 40 ? 140.588 520.884 47.718 1.00 24.14 ? 69 ALA B O 1 ATOM 7284 C CB . ALA B 2 40 ? 142.949 519.128 48.662 1.00 27.00 ? 69 ALA B CB 1 ATOM 7285 N N . CYS B 2 41 ? 139.907 518.768 47.309 1.00 23.63 ? 70 CYS B N 1 ATOM 7286 C CA . CYS B 2 41 ? 139.054 519.127 46.174 1.00 23.32 ? 70 CYS B CA 1 ATOM 7287 C C . CYS B 2 41 ? 137.590 519.264 46.557 1.00 30.54 ? 70 CYS B C 1 ATOM 7288 O O . CYS B 2 41 ? 137.069 518.414 47.282 1.00 31.23 ? 70 CYS B O 1 ATOM 7289 C CB . CYS B 2 41 ? 139.236 518.150 45.015 1.00 22.43 ? 70 CYS B CB 1 ATOM 7290 S SG . CYS B 2 41 ? 140.846 518.255 44.174 1.00 24.99 ? 70 CYS B SG 1 ATOM 7291 N N . PRO B 2 42 ? 136.901 520.306 46.036 1.00 27.83 ? 71 PRO B N 1 ATOM 7292 C CA . PRO B 2 42 ? 135.492 520.513 46.407 1.00 28.40 ? 71 PRO B CA 1 ATOM 7293 C C . PRO B 2 42 ? 134.507 519.538 45.756 1.00 35.27 ? 71 PRO B C 1 ATOM 7294 O O . PRO B 2 42 ? 133.350 519.454 46.164 1.00 36.65 ? 71 PRO B O 1 ATOM 7295 C CB . PRO B 2 42 ? 135.238 521.965 45.992 1.00 29.78 ? 71 PRO B CB 1 ATOM 7296 C CG . PRO B 2 42 ? 136.190 522.196 44.852 1.00 32.63 ? 71 PRO B CG 1 ATOM 7297 C CD . PRO B 2 42 ? 137.405 521.407 45.184 1.00 28.20 ? 71 PRO B CD 1 ATOM 7298 N N . ASN B 2 43 ? 134.961 518.799 44.750 1.00 31.95 ? 72 ASN B N 1 ATOM 7299 C CA . ASN B 2 43 ? 134.119 517.869 44.017 1.00 30.89 ? 72 ASN B CA 1 ATOM 7300 C C . ASN B 2 43 ? 134.734 516.474 43.967 1.00 34.63 ? 72 ASN B C 1 ATOM 7301 O O . ASN B 2 43 ? 134.366 515.644 43.114 1.00 34.84 ? 72 ASN B O 1 ATOM 7302 C CB . ASN B 2 43 ? 133.901 518.421 42.611 1.00 30.74 ? 72 ASN B CB 1 ATOM 7303 C CG . ASN B 2 43 ? 135.175 518.613 41.839 1.00 41.29 ? 72 ASN B CG 1 ATOM 7304 O OD1 . ASN B 2 43 ? 136.294 518.644 42.385 1.00 39.22 ? 72 ASN B OD1 1 ATOM 7305 N ND2 . ASN B 2 43 ? 135.020 518.749 40.545 1.00 23.37 ? 72 ASN B ND2 1 ATOM 7306 N N . GLY B 2 44 ? 135.660 516.218 44.873 1.00 29.87 ? 73 GLY B N 1 ATOM 7307 C CA . GLY B 2 44 ? 136.316 514.933 44.903 1.00 30.23 ? 73 GLY B CA 1 ATOM 7308 C C . GLY B 2 44 ? 135.498 513.892 45.628 1.00 38.26 ? 73 GLY B C 1 ATOM 7309 O O . GLY B 2 44 ? 134.475 514.194 46.266 1.00 37.50 ? 73 GLY B O 1 ATOM 7310 N N . SER B 2 45 ? 135.970 512.645 45.548 1.00 36.01 ? 74 SER B N 1 ATOM 7311 C CA . SER B 2 45 ? 135.355 511.570 46.293 1.00 34.92 ? 74 SER B CA 1 ATOM 7312 C C . SER B 2 45 ? 136.428 510.671 46.888 1.00 35.59 ? 74 SER B C 1 ATOM 7313 O O . SER B 2 45 ? 137.559 510.573 46.370 1.00 36.48 ? 74 SER B O 1 ATOM 7314 C CB . SER B 2 45 ? 134.293 510.840 45.476 1.00 39.75 ? 74 SER B CB 1 ATOM 7315 O OG . SER B 2 45 ? 134.856 510.001 44.483 1.00 52.92 ? 74 SER B OG 1 ATOM 7316 N N . PHE B 2 46 ? 136.111 510.119 48.047 1.00 28.07 ? 75 PHE B N 1 ATOM 7317 C CA . PHE B 2 46 ? 136.995 509.230 48.784 1.00 26.10 ? 75 PHE B CA 1 ATOM 7318 C C . PHE B 2 46 ? 136.339 507.884 48.816 1.00 31.07 ? 75 PHE B C 1 ATOM 7319 O O . PHE B 2 46 ? 135.144 507.770 49.143 1.00 29.05 ? 75 PHE B O 1 ATOM 7320 C CB . PHE B 2 46 ? 137.183 509.734 50.206 1.00 26.81 ? 75 PHE B CB 1 ATOM 7321 C CG . PHE B 2 46 ? 138.062 508.850 51.057 1.00 27.29 ? 75 PHE B CG 1 ATOM 7322 C CD1 . PHE B 2 46 ? 139.443 509.004 51.049 1.00 29.30 ? 75 PHE B CD1 1 ATOM 7323 C CD2 . PHE B 2 46 ? 137.508 507.885 51.895 1.00 27.21 ? 75 PHE B CD2 1 ATOM 7324 C CE1 . PHE B 2 46 ? 140.252 508.206 51.845 1.00 28.44 ? 75 PHE B CE1 1 ATOM 7325 C CE2 . PHE B 2 46 ? 138.319 507.093 52.692 1.00 29.17 ? 75 PHE B CE2 1 ATOM 7326 C CZ . PHE B 2 46 ? 139.685 507.262 52.666 1.00 27.45 ? 75 PHE B CZ 1 ATOM 7327 N N . HIS B 2 47 ? 137.120 506.861 48.508 1.00 29.43 ? 76 HIS B N 1 ATOM 7328 C CA . HIS B 2 47 ? 136.628 505.502 48.460 1.00 30.07 ? 76 HIS B CA 1 ATOM 7329 C C . HIS B 2 47 ? 136.858 504.772 49.790 1.00 31.29 ? 76 HIS B C 1 ATOM 7330 O O . HIS B 2 47 ? 138.006 504.651 50.246 1.00 28.59 ? 76 HIS B O 1 ATOM 7331 C CB . HIS B 2 47 ? 137.296 504.782 47.288 1.00 32.22 ? 76 HIS B CB 1 ATOM 7332 C CG . HIS B 2 47 ? 136.824 503.385 47.070 1.00 36.28 ? 76 HIS B CG 1 ATOM 7333 N ND1 . HIS B 2 47 ? 137.626 502.299 47.372 1.00 38.07 ? 76 HIS B ND1 1 ATOM 7334 C CD2 . HIS B 2 47 ? 135.645 502.941 46.578 1.00 39.08 ? 76 HIS B CD2 1 ATOM 7335 C CE1 . HIS B 2 47 ? 136.909 501.230 47.067 1.00 38.35 ? 76 HIS B CE1 1 ATOM 7336 N NE2 . HIS B 2 47 ? 135.714 501.566 46.574 1.00 38.95 ? 76 HIS B NE2 1 ATOM 7337 N N . CYS B 2 48 ? 135.751 504.348 50.434 1.00 28.05 ? 77 CYS B N 1 ATOM 7338 C CA . CYS B 2 48 ? 135.753 503.525 51.648 1.00 29.91 ? 77 CYS B CA 1 ATOM 7339 C C . CYS B 2 48 ? 135.922 502.104 51.126 1.00 32.20 ? 77 CYS B C 1 ATOM 7340 O O . CYS B 2 48 ? 134.988 501.537 50.551 1.00 30.29 ? 77 CYS B O 1 ATOM 7341 C CB . CYS B 2 48 ? 134.439 503.631 52.426 1.00 32.36 ? 77 CYS B CB 1 ATOM 7342 S SG . CYS B 2 48 ? 133.892 505.316 52.836 1.00 37.22 ? 77 CYS B SG 1 ATOM 7343 N N . THR B 2 49 ? 137.092 501.527 51.323 1.00 30.93 ? 78 THR B N 1 ATOM 7344 C CA . THR B 2 49 ? 137.354 500.200 50.798 1.00 31.89 ? 78 THR B CA 1 ATOM 7345 C C . THR B 2 49 ? 136.479 499.146 51.492 1.00 37.00 ? 78 THR B C 1 ATOM 7346 O O . THR B 2 49 ? 135.976 498.242 50.828 1.00 37.23 ? 78 THR B O 1 ATOM 7347 C CB . THR B 2 49 ? 138.847 499.902 50.787 1.00 41.76 ? 78 THR B CB 1 ATOM 7348 O OG1 . THR B 2 49 ? 139.041 498.677 50.079 1.00 41.66 ? 78 THR B OG1 1 ATOM 7349 C CG2 . THR B 2 49 ? 139.450 499.812 52.180 1.00 44.43 ? 78 THR B CG2 1 ATOM 7350 N N . ASN B 2 50 ? 136.239 499.320 52.804 1.00 34.52 ? 79 ASN B N 1 ATOM 7351 C CA . ASN B 2 50 ? 135.394 498.464 53.635 1.00 33.53 ? 79 ASN B CA 1 ATOM 7352 C C . ASN B 2 50 ? 135.641 497.001 53.345 1.00 39.71 ? 79 ASN B C 1 ATOM 7353 O O . ASN B 2 50 ? 134.719 496.257 52.989 1.00 39.58 ? 79 ASN B O 1 ATOM 7354 C CB . ASN B 2 50 ? 133.918 498.835 53.496 1.00 30.10 ? 79 ASN B CB 1 ATOM 7355 C CG . ASN B 2 50 ? 133.561 500.266 53.885 1.00 39.55 ? 79 ASN B CG 1 ATOM 7356 O OD1 . ASN B 2 50 ? 134.197 500.912 54.732 1.00 27.14 ? 79 ASN B OD1 1 ATOM 7357 N ND2 . ASN B 2 50 ? 132.475 500.762 53.330 1.00 31.24 ? 79 ASN B ND2 1 ATOM 7358 N N . THR B 2 51 ? 136.920 496.609 53.471 1.00 38.23 ? 80 THR B N 1 ATOM 7359 C CA . THR B 2 51 ? 137.438 495.261 53.269 1.00 38.72 ? 80 THR B CA 1 ATOM 7360 C C . THR B 2 51 ? 136.497 494.236 53.885 1.00 42.37 ? 80 THR B C 1 ATOM 7361 O O . THR B 2 51 ? 136.204 494.309 55.083 1.00 42.91 ? 80 THR B O 1 ATOM 7362 C CB . THR B 2 51 ? 138.840 495.160 53.869 1.00 47.43 ? 80 THR B CB 1 ATOM 7363 O OG1 . THR B 2 51 ? 139.647 496.249 53.416 1.00 46.06 ? 80 THR B OG1 1 ATOM 7364 C CG2 . THR B 2 51 ? 139.499 493.858 53.536 1.00 47.43 ? 80 THR B CG2 1 ATOM 7365 N N . GLY B 2 52 ? 135.976 493.361 53.036 1.00 38.57 ? 81 GLY B N 1 ATOM 7366 C CA . GLY B 2 52 ? 135.051 492.302 53.427 1.00 38.25 ? 81 GLY B CA 1 ATOM 7367 C C . GLY B 2 52 ? 133.579 492.617 53.263 1.00 42.15 ? 81 GLY B C 1 ATOM 7368 O O . GLY B 2 52 ? 132.746 491.713 53.371 1.00 39.60 ? 81 GLY B O 1 ATOM 7369 N N . TYR B 2 53 ? 133.240 493.916 53.025 1.00 40.90 ? 82 TYR B N 1 ATOM 7370 C CA . TYR B 2 53 ? 131.856 494.405 52.950 1.00 40.44 ? 82 TYR B CA 1 ATOM 7371 C C . TYR B 2 53 ? 131.675 495.328 51.761 1.00 45.73 ? 82 TYR B C 1 ATOM 7372 O O . TYR B 2 53 ? 132.599 495.455 50.953 1.00 45.60 ? 82 TYR B O 1 ATOM 7373 C CB . TYR B 2 53 ? 131.460 495.075 54.285 1.00 40.68 ? 82 TYR B CB 1 ATOM 7374 C CG . TYR B 2 53 ? 131.737 494.237 55.520 1.00 39.95 ? 82 TYR B CG 1 ATOM 7375 C CD1 . TYR B 2 53 ? 133.003 494.212 56.102 1.00 41.51 ? 82 TYR B CD1 1 ATOM 7376 C CD2 . TYR B 2 53 ? 130.725 493.500 56.131 1.00 40.80 ? 82 TYR B CD2 1 ATOM 7377 C CE1 . TYR B 2 53 ? 133.269 493.436 57.227 1.00 41.95 ? 82 TYR B CE1 1 ATOM 7378 C CE2 . TYR B 2 53 ? 130.978 492.724 57.264 1.00 42.17 ? 82 TYR B CE2 1 ATOM 7379 C CZ . TYR B 2 53 ? 132.256 492.692 57.806 1.00 49.50 ? 82 TYR B CZ 1 ATOM 7380 O OH . TYR B 2 53 ? 132.533 491.954 58.934 1.00 48.32 ? 82 TYR B OH 1 ATOM 7381 N N . LYS B 2 54 ? 130.478 495.904 51.585 1.00 44.20 ? 83 LYS B N 1 ATOM 7382 C CA . LYS B 2 54 ? 130.262 496.730 50.401 1.00 44.37 ? 83 LYS B CA 1 ATOM 7383 C C . LYS B 2 54 ? 131.056 498.032 50.465 1.00 48.51 ? 83 LYS B C 1 ATOM 7384 O O . LYS B 2 54 ? 131.005 498.717 51.491 1.00 48.53 ? 83 LYS B O 1 ATOM 7385 C CB . LYS B 2 54 ? 128.776 496.970 50.095 1.00 46.37 ? 83 LYS B CB 1 ATOM 7386 C CG . LYS B 2 54 ? 127.992 497.675 51.191 1.00 58.19 ? 83 LYS B CG 1 ATOM 7387 C CD . LYS B 2 54 ? 126.908 498.613 50.609 1.00 70.31 ? 83 LYS B CD 1 ATOM 7388 C CE . LYS B 2 54 ? 125.923 497.958 49.657 1.00 78.24 ? 83 LYS B CE 1 ATOM 7389 N NZ . LYS B 2 54 ? 125.163 498.969 48.871 1.00 82.34 ? 83 LYS B NZ 1 ATOM 7390 N N . PRO B 2 55 ? 131.841 498.348 49.407 1.00 43.24 ? 84 PRO B N 1 ATOM 7391 C CA . PRO B 2 55 ? 132.566 499.623 49.386 1.00 42.02 ? 84 PRO B CA 1 ATOM 7392 C C . PRO B 2 55 ? 131.601 500.805 49.161 1.00 44.65 ? 84 PRO B C 1 ATOM 7393 O O . PRO B 2 55 ? 130.558 500.648 48.524 1.00 45.28 ? 84 PRO B O 1 ATOM 7394 C CB . PRO B 2 55 ? 133.504 499.444 48.203 1.00 43.64 ? 84 PRO B CB 1 ATOM 7395 C CG . PRO B 2 55 ? 132.743 498.584 47.259 1.00 47.95 ? 84 PRO B CG 1 ATOM 7396 C CD . PRO B 2 55 ? 132.004 497.620 48.128 1.00 44.28 ? 84 PRO B CD 1 ATOM 7397 N N . LEU B 2 56 ? 131.947 501.990 49.673 1.00 39.42 ? 85 LEU B N 1 ATOM 7398 C CA . LEU B 2 56 ? 131.113 503.210 49.589 1.00 37.75 ? 85 LEU B CA 1 ATOM 7399 C C . LEU B 2 56 ? 132.039 504.360 49.172 1.00 38.81 ? 85 LEU B C 1 ATOM 7400 O O . LEU B 2 56 ? 133.245 504.296 49.401 1.00 37.83 ? 85 LEU B O 1 ATOM 7401 C CB . LEU B 2 56 ? 130.502 503.465 51.012 1.00 37.67 ? 85 LEU B CB 1 ATOM 7402 C CG . LEU B 2 56 ? 129.598 504.691 51.365 1.00 42.97 ? 85 LEU B CG 1 ATOM 7403 C CD1 . LEU B 2 56 ? 128.107 504.366 51.142 1.00 43.85 ? 85 LEU B CD1 1 ATOM 7404 C CD2 . LEU B 2 56 ? 129.772 505.109 52.858 1.00 44.06 ? 85 LEU B CD2 1 ATOM 7405 N N . TYR B 2 57 ? 131.492 505.363 48.510 1.00 35.35 ? 86 TYR B N 1 ATOM 7406 C CA . TYR B 2 57 ? 132.227 506.575 48.189 1.00 34.92 ? 86 TYR B CA 1 ATOM 7407 C C . TYR B 2 57 ? 131.609 507.665 49.009 1.00 35.69 ? 86 TYR B C 1 ATOM 7408 O O . TYR B 2 57 ? 130.389 507.708 49.166 1.00 35.31 ? 86 TYR B O 1 ATOM 7409 C CB . TYR B 2 57 ? 132.075 506.963 46.731 1.00 36.78 ? 86 TYR B CB 1 ATOM 7410 C CG . TYR B 2 57 ? 132.991 506.223 45.796 1.00 40.31 ? 86 TYR B CG 1 ATOM 7411 C CD1 . TYR B 2 57 ? 134.275 506.698 45.524 1.00 41.58 ? 86 TYR B CD1 1 ATOM 7412 C CD2 . TYR B 2 57 ? 132.545 505.103 45.098 1.00 42.12 ? 86 TYR B CD2 1 ATOM 7413 C CE1 . TYR B 2 57 ? 135.106 506.053 44.611 1.00 41.39 ? 86 TYR B CE1 1 ATOM 7414 C CE2 . TYR B 2 57 ? 133.375 504.441 44.190 1.00 43.29 ? 86 TYR B CE2 1 ATOM 7415 C CZ . TYR B 2 57 ? 134.656 504.920 43.953 1.00 49.59 ? 86 TYR B CZ 1 ATOM 7416 O OH . TYR B 2 57 ? 135.483 504.289 43.058 1.00 52.08 ? 86 TYR B OH 1 ATOM 7417 N N . ILE B 2 58 ? 132.430 508.556 49.523 1.00 29.56 ? 87 ILE B N 1 ATOM 7418 C CA . ILE B 2 58 ? 131.940 509.707 50.270 1.00 28.21 ? 87 ILE B CA 1 ATOM 7419 C C . ILE B 2 58 ? 132.514 510.995 49.662 1.00 30.72 ? 87 ILE B C 1 ATOM 7420 O O . ILE B 2 58 ? 133.496 510.957 48.909 1.00 28.82 ? 87 ILE B O 1 ATOM 7421 C CB . ILE B 2 58 ? 132.290 509.600 51.768 1.00 30.30 ? 87 ILE B CB 1 ATOM 7422 C CG1 . ILE B 2 58 ? 133.825 509.587 51.961 1.00 29.21 ? 87 ILE B CG1 1 ATOM 7423 C CG2 . ILE B 2 58 ? 131.591 508.403 52.422 1.00 30.32 ? 87 ILE B CG2 1 ATOM 7424 C CD1 . ILE B 2 58 ? 134.304 509.846 53.321 1.00 22.70 ? 87 ILE B CD1 1 ATOM 7425 N N . LEU B 2 59 ? 131.931 512.132 50.032 1.00 27.50 ? 88 LEU B N 1 ATOM 7426 C CA . LEU B 2 59 ? 132.470 513.436 49.641 1.00 26.58 ? 88 LEU B CA 1 ATOM 7427 C C . LEU B 2 59 ? 133.901 513.613 50.194 1.00 28.86 ? 88 LEU B C 1 ATOM 7428 O O . LEU B 2 59 ? 134.160 513.273 51.343 1.00 27.22 ? 88 LEU B O 1 ATOM 7429 C CB . LEU B 2 59 ? 131.595 514.573 50.215 1.00 26.41 ? 88 LEU B CB 1 ATOM 7430 C CG . LEU B 2 59 ? 130.172 514.637 49.705 1.00 31.33 ? 88 LEU B CG 1 ATOM 7431 C CD1 . LEU B 2 59 ? 129.403 515.723 50.404 1.00 30.67 ? 88 LEU B CD1 1 ATOM 7432 C CD2 . LEU B 2 59 ? 130.127 514.872 48.208 1.00 32.10 ? 88 LEU B CD2 1 ATOM 7433 N N . SER B 2 60 ? 134.808 514.200 49.400 1.00 26.35 ? 89 SER B N 1 ATOM 7434 C CA . SER B 2 60 ? 136.154 514.559 49.864 1.00 25.17 ? 89 SER B CA 1 ATOM 7435 C C . SER B 2 60 ? 136.140 515.430 51.121 1.00 28.40 ? 89 SER B C 1 ATOM 7436 O O . SER B 2 60 ? 137.023 515.284 51.968 1.00 28.38 ? 89 SER B O 1 ATOM 7437 C CB . SER B 2 60 ? 136.883 515.335 48.788 1.00 27.28 ? 89 SER B CB 1 ATOM 7438 O OG . SER B 2 60 ? 137.323 514.417 47.817 1.00 38.75 ? 89 SER B OG 1 ATOM 7439 N N . SER B 2 61 ? 135.149 516.343 51.239 1.00 24.78 ? 90 SER B N 1 ATOM 7440 C CA . SER B 2 61 ? 134.963 517.221 52.405 1.00 23.73 ? 90 SER B CA 1 ATOM 7441 C C . SER B 2 61 ? 134.737 516.454 53.700 1.00 27.18 ? 90 SER B C 1 ATOM 7442 O O . SER B 2 61 ? 134.858 517.025 54.778 1.00 28.50 ? 90 SER B O 1 ATOM 7443 C CB . SER B 2 61 ? 133.843 518.227 52.169 1.00 26.32 ? 90 SER B CB 1 ATOM 7444 O OG . SER B 2 61 ? 132.601 517.583 51.986 1.00 34.70 ? 90 SER B OG 1 ATOM 7445 N N . ARG B 2 62 ? 134.496 515.146 53.605 1.00 21.64 ? 91 ARG B N 1 ATOM 7446 C CA . ARG B 2 62 ? 134.328 514.270 54.764 1.00 19.33 ? 91 ARG B CA 1 ATOM 7447 C C . ARG B 2 62 ? 135.586 513.454 55.135 1.00 22.65 ? 91 ARG B C 1 ATOM 7448 O O . ARG B 2 62 ? 135.530 512.617 56.026 1.00 22.61 ? 91 ARG B O 1 ATOM 7449 C CB . ARG B 2 62 ? 133.090 513.395 54.570 1.00 14.20 ? 91 ARG B CB 1 ATOM 7450 C CG . ARG B 2 62 ? 131.899 514.325 54.569 1.00 20.74 ? 91 ARG B CG 1 ATOM 7451 C CD . ARG B 2 62 ? 130.560 513.714 54.401 1.00 32.48 ? 91 ARG B CD 1 ATOM 7452 N NE . ARG B 2 62 ? 129.577 514.763 54.136 1.00 38.05 ? 91 ARG B NE 1 ATOM 7453 C CZ . ARG B 2 62 ? 128.281 514.540 53.951 1.00 45.37 ? 91 ARG B CZ 1 ATOM 7454 N NH1 . ARG B 2 62 ? 127.797 513.307 54.027 1.00 30.89 ? 91 ARG B NH1 1 ATOM 7455 N NH2 . ARG B 2 62 ? 127.462 515.547 53.671 1.00 20.00 ? 91 ARG B NH2 1 ATOM 7456 N N . VAL B 2 63 ? 136.720 513.754 54.512 1.00 21.36 ? 92 VAL B N 1 ATOM 7457 C CA . VAL B 2 63 ? 138.003 513.113 54.804 1.00 21.89 ? 92 VAL B CA 1 ATOM 7458 C C . VAL B 2 63 ? 138.628 513.935 55.889 1.00 27.13 ? 92 VAL B C 1 ATOM 7459 O O . VAL B 2 63 ? 138.832 515.149 55.715 1.00 26.66 ? 92 VAL B O 1 ATOM 7460 C CB . VAL B 2 63 ? 138.931 513.023 53.557 1.00 25.45 ? 92 VAL B CB 1 ATOM 7461 C CG1 . VAL B 2 63 ? 140.298 512.460 53.915 1.00 24.61 ? 92 VAL B CG1 1 ATOM 7462 C CG2 . VAL B 2 63 ? 138.300 512.179 52.467 1.00 25.71 ? 92 VAL B CG2 1 ATOM 7463 N N . ASN B 2 64 ? 138.931 513.287 57.012 1.00 24.20 ? 93 ASN B N 1 ATOM 7464 C CA . ASN B 2 64 ? 139.542 513.953 58.165 1.00 24.00 ? 93 ASN B CA 1 ATOM 7465 C C . ASN B 2 64 ? 138.717 515.144 58.668 1.00 27.44 ? 93 ASN B C 1 ATOM 7466 O O . ASN B 2 64 ? 139.272 516.181 59.038 1.00 28.24 ? 93 ASN B O 1 ATOM 7467 C CB . ASN B 2 64 ? 141.007 514.324 57.879 1.00 20.88 ? 93 ASN B CB 1 ATOM 7468 C CG . ASN B 2 64 ? 141.898 513.109 57.816 1.00 34.96 ? 93 ASN B CG 1 ATOM 7469 O OD1 . ASN B 2 64 ? 141.747 512.139 58.581 1.00 29.05 ? 93 ASN B OD1 1 ATOM 7470 N ND2 . ASN B 2 64 ? 142.844 513.123 56.899 1.00 23.30 ? 93 ASN B ND2 1 ATOM 7471 N N . ASP B 2 65 ? 137.385 514.989 58.679 1.00 22.37 ? 94 ASP B N 1 ATOM 7472 C CA . ASP B 2 65 ? 136.509 516.028 59.213 1.00 21.20 ? 94 ASP B CA 1 ATOM 7473 C C . ASP B 2 65 ? 136.189 515.782 60.679 1.00 26.67 ? 94 ASP B C 1 ATOM 7474 O O . ASP B 2 65 ? 135.473 516.575 61.268 1.00 25.58 ? 94 ASP B O 1 ATOM 7475 C CB . ASP B 2 65 ? 135.223 516.177 58.382 1.00 21.01 ? 94 ASP B CB 1 ATOM 7476 C CG . ASP B 2 65 ? 134.330 514.968 58.309 1.00 20.17 ? 94 ASP B CG 1 ATOM 7477 O OD1 . ASP B 2 65 ? 134.705 513.905 58.842 1.00 24.19 ? 94 ASP B OD1 1 ATOM 7478 O OD2 . ASP B 2 65 ? 133.263 515.079 57.736 1.00 24.62 ? 94 ASP B OD2 1 ATOM 7479 N N . GLY B 2 66 ? 136.715 514.692 61.238 1.00 24.98 ? 95 GLY B N 1 ATOM 7480 C CA . GLY B 2 66 ? 136.476 514.286 62.616 1.00 25.47 ? 95 GLY B CA 1 ATOM 7481 C C . GLY B 2 66 ? 135.209 513.472 62.821 1.00 29.54 ? 95 GLY B C 1 ATOM 7482 O O . GLY B 2 66 ? 134.882 513.134 63.954 1.00 29.20 ? 95 GLY B O 1 ATOM 7483 N N . VAL B 2 67 ? 134.486 513.147 61.739 1.00 27.40 ? 96 VAL B N 1 ATOM 7484 C CA . VAL B 2 67 ? 133.246 512.347 61.777 1.00 27.37 ? 96 VAL B CA 1 ATOM 7485 C C . VAL B 2 67 ? 133.551 511.014 61.104 1.00 31.70 ? 96 VAL B C 1 ATOM 7486 O O . VAL B 2 67 ? 134.253 511.004 60.090 1.00 30.35 ? 96 VAL B O 1 ATOM 7487 C CB . VAL B 2 67 ? 132.097 513.088 61.040 1.00 31.10 ? 96 VAL B CB 1 ATOM 7488 C CG1 . VAL B 2 67 ? 130.794 512.288 61.057 1.00 31.13 ? 96 VAL B CG1 1 ATOM 7489 C CG2 . VAL B 2 67 ? 131.880 514.483 61.622 1.00 30.50 ? 96 VAL B CG2 1 ATOM 7490 N N . CYS B 2 68 ? 133.011 509.908 61.628 1.00 29.44 ? 97 CYS B N 1 ATOM 7491 C CA . CYS B 2 68 ? 133.246 508.597 61.043 1.00 30.59 ? 97 CYS B CA 1 ATOM 7492 C C . CYS B 2 68 ? 132.277 508.354 59.917 1.00 31.59 ? 97 CYS B C 1 ATOM 7493 O O . CYS B 2 68 ? 131.119 508.083 60.180 1.00 32.02 ? 97 CYS B O 1 ATOM 7494 C CB . CYS B 2 68 ? 133.164 507.507 62.109 1.00 32.93 ? 97 CYS B CB 1 ATOM 7495 S SG . CYS B 2 68 ? 134.360 507.706 63.461 1.00 37.98 ? 97 CYS B SG 1 ATOM 7496 N N . ASP B 2 69 ? 132.733 508.443 58.655 1.00 27.30 ? 98 ASP B N 1 ATOM 7497 C CA . ASP B 2 69 ? 131.853 508.228 57.500 1.00 26.56 ? 98 ASP B CA 1 ATOM 7498 C C . ASP B 2 69 ? 131.889 506.815 56.928 1.00 31.70 ? 98 ASP B C 1 ATOM 7499 O O . ASP B 2 69 ? 130.856 506.271 56.531 1.00 30.74 ? 98 ASP B O 1 ATOM 7500 C CB . ASP B 2 69 ? 132.128 509.255 56.411 1.00 27.29 ? 98 ASP B CB 1 ATOM 7501 C CG . ASP B 2 69 ? 131.779 510.655 56.865 1.00 28.13 ? 98 ASP B CG 1 ATOM 7502 O OD1 . ASP B 2 69 ? 130.593 511.030 56.757 1.00 25.15 ? 98 ASP B OD1 1 ATOM 7503 O OD2 . ASP B 2 69 ? 132.692 511.362 57.367 1.00 26.17 ? 98 ASP B OD2 1 ATOM 7504 N N . CYS B 2 70 ? 133.079 506.235 56.856 1.00 31.21 ? 99 CYS B N 1 ATOM 7505 C CA . CYS B 2 70 ? 133.253 504.896 56.318 1.00 32.53 ? 99 CYS B CA 1 ATOM 7506 C C . CYS B 2 70 ? 133.060 503.954 57.457 1.00 37.69 ? 99 CYS B C 1 ATOM 7507 O O . CYS B 2 70 ? 133.658 504.182 58.520 1.00 36.30 ? 99 CYS B O 1 ATOM 7508 C CB . CYS B 2 70 ? 134.645 504.695 55.723 1.00 33.21 ? 99 CYS B CB 1 ATOM 7509 S SG . CYS B 2 70 ? 135.105 505.803 54.367 1.00 36.91 ? 99 CYS B SG 1 ATOM 7510 N N . CYS B 2 71 ? 132.356 502.819 57.212 1.00 35.55 ? 100 CYS B N 1 ATOM 7511 C CA . CYS B 2 71 ? 132.234 501.830 58.263 1.00 35.95 ? 100 CYS B CA 1 ATOM 7512 C C . CYS B 2 71 ? 133.637 501.314 58.695 1.00 35.27 ? 100 CYS B C 1 ATOM 7513 O O . CYS B 2 71 ? 133.842 501.062 59.886 1.00 33.13 ? 100 CYS B O 1 ATOM 7514 C CB . CYS B 2 71 ? 131.255 500.717 57.893 1.00 37.96 ? 100 CYS B CB 1 ATOM 7515 S SG . CYS B 2 71 ? 131.821 499.577 56.594 1.00 42.95 ? 100 CYS B SG 1 ATOM 7516 N N . ASP B 2 72 ? 134.637 501.276 57.769 1.00 29.23 ? 101 ASP B N 1 ATOM 7517 C CA . ASP B 2 72 ? 136.004 500.843 58.140 1.00 28.79 ? 101 ASP B CA 1 ATOM 7518 C C . ASP B 2 72 ? 136.855 501.920 58.845 1.00 33.17 ? 101 ASP B C 1 ATOM 7519 O O . ASP B 2 72 ? 137.996 501.630 59.226 1.00 33.22 ? 101 ASP B O 1 ATOM 7520 C CB . ASP B 2 72 ? 136.767 500.275 56.928 1.00 30.85 ? 101 ASP B CB 1 ATOM 7521 C CG . ASP B 2 72 ? 137.115 501.274 55.828 1.00 44.62 ? 101 ASP B CG 1 ATOM 7522 O OD1 . ASP B 2 72 ? 136.918 502.502 56.039 1.00 43.95 ? 101 ASP B OD1 1 ATOM 7523 O OD2 . ASP B 2 72 ? 137.610 500.835 54.763 1.00 50.74 ? 101 ASP B OD2 1 ATOM 7524 N N . GLY B 2 73 ? 136.322 503.153 58.925 1.00 29.53 ? 102 GLY B N 1 ATOM 7525 C CA . GLY B 2 73 ? 136.958 504.317 59.540 1.00 28.28 ? 102 GLY B CA 1 ATOM 7526 C C . GLY B 2 73 ? 138.144 504.923 58.817 1.00 31.62 ? 102 GLY B C 1 ATOM 7527 O O . GLY B 2 73 ? 138.785 505.830 59.365 1.00 31.46 ? 102 GLY B O 1 ATOM 7528 N N . THR B 2 74 ? 138.428 504.476 57.557 1.00 27.03 ? 103 THR B N 1 ATOM 7529 C CA . THR B 2 74 ? 139.610 504.917 56.807 1.00 25.68 ? 103 THR B CA 1 ATOM 7530 C C . THR B 2 74 ? 139.572 506.388 56.396 1.00 28.41 ? 103 THR B C 1 ATOM 7531 O O . THR B 2 74 ? 140.606 506.927 56.012 1.00 27.19 ? 103 THR B O 1 ATOM 7532 C CB . THR B 2 74 ? 139.919 504.015 55.620 1.00 31.05 ? 103 THR B CB 1 ATOM 7533 O OG1 . THR B 2 74 ? 138.786 503.934 54.744 1.00 35.72 ? 103 THR B OG1 1 ATOM 7534 C CG2 . THR B 2 74 ? 140.364 502.632 56.059 1.00 28.75 ? 103 THR B CG2 1 ATOM 7535 N N . ASP B 2 75 ? 138.401 507.038 56.472 1.00 24.65 ? 104 ASP B N 1 ATOM 7536 C CA . ASP B 2 75 ? 138.275 508.466 56.141 1.00 23.05 ? 104 ASP B CA 1 ATOM 7537 C C . ASP B 2 75 ? 138.903 509.354 57.202 1.00 26.61 ? 104 ASP B C 1 ATOM 7538 O O . ASP B 2 75 ? 139.192 510.516 56.931 1.00 23.32 ? 104 ASP B O 1 ATOM 7539 C CB . ASP B 2 75 ? 136.803 508.853 55.912 1.00 23.84 ? 104 ASP B CB 1 ATOM 7540 C CG . ASP B 2 75 ? 135.874 508.521 57.069 1.00 28.34 ? 104 ASP B CG 1 ATOM 7541 O OD1 . ASP B 2 75 ? 135.775 507.335 57.433 1.00 26.66 ? 104 ASP B OD1 1 ATOM 7542 O OD2 . ASP B 2 75 ? 135.185 509.429 57.548 1.00 30.03 ? 104 ASP B OD2 1 ATOM 7543 N N . GLU B 2 76 ? 139.098 508.808 58.425 1.00 25.55 ? 105 GLU B N 1 ATOM 7544 C CA . GLU B 2 76 ? 139.682 509.525 59.558 1.00 24.12 ? 105 GLU B CA 1 ATOM 7545 C C . GLU B 2 76 ? 141.045 508.952 59.870 1.00 27.95 ? 105 GLU B C 1 ATOM 7546 O O . GLU B 2 76 ? 141.164 508.029 60.654 1.00 28.28 ? 105 GLU B O 1 ATOM 7547 C CB . GLU B 2 76 ? 138.713 509.500 60.755 1.00 24.62 ? 105 GLU B CB 1 ATOM 7548 C CG . GLU B 2 76 ? 137.377 510.144 60.434 1.00 23.14 ? 105 GLU B CG 1 ATOM 7549 C CD . GLU B 2 76 ? 137.464 511.581 59.970 1.00 31.20 ? 105 GLU B CD 1 ATOM 7550 O OE1 . GLU B 2 76 ? 138.162 512.363 60.648 1.00 23.95 ? 105 GLU B OE1 1 ATOM 7551 O OE2 . GLU B 2 76 ? 136.856 511.924 58.928 1.00 24.80 ? 105 GLU B OE2 1 ATOM 7552 N N . TYR B 2 77 ? 142.075 509.447 59.193 1.00 24.80 ? 106 TYR B N 1 ATOM 7553 C CA . TYR B 2 77 ? 143.403 508.901 59.378 1.00 23.69 ? 106 TYR B CA 1 ATOM 7554 C C . TYR B 2 77 ? 144.362 509.864 60.047 1.00 29.40 ? 106 TYR B C 1 ATOM 7555 O O . TYR B 2 77 ? 145.420 509.432 60.530 1.00 28.32 ? 106 TYR B O 1 ATOM 7556 C CB . TYR B 2 77 ? 143.965 508.359 58.057 1.00 23.82 ? 106 TYR B CB 1 ATOM 7557 C CG . TYR B 2 77 ? 144.090 509.366 56.931 1.00 25.21 ? 106 TYR B CG 1 ATOM 7558 C CD1 . TYR B 2 77 ? 145.222 510.173 56.811 1.00 26.49 ? 106 TYR B CD1 1 ATOM 7559 C CD2 . TYR B 2 77 ? 143.144 509.414 55.906 1.00 25.39 ? 106 TYR B CD2 1 ATOM 7560 C CE1 . TYR B 2 77 ? 145.372 511.050 55.738 1.00 26.40 ? 106 TYR B CE1 1 ATOM 7561 C CE2 . TYR B 2 77 ? 143.270 510.304 54.849 1.00 26.07 ? 106 TYR B CE2 1 ATOM 7562 C CZ . TYR B 2 77 ? 144.391 511.112 54.763 1.00 26.92 ? 106 TYR B CZ 1 ATOM 7563 O OH . TYR B 2 77 ? 144.521 511.957 53.711 1.00 19.42 ? 106 TYR B OH 1 ATOM 7564 N N . ASN B 2 78 ? 144.009 511.156 60.074 1.00 27.30 ? 107 ASN B N 1 ATOM 7565 C CA . ASN B 2 78 ? 144.867 512.172 60.657 1.00 27.70 ? 107 ASN B CA 1 ATOM 7566 C C . ASN B 2 78 ? 144.005 513.344 61.144 1.00 35.01 ? 107 ASN B C 1 ATOM 7567 O O . ASN B 2 78 ? 144.189 514.504 60.739 1.00 35.39 ? 107 ASN B O 1 ATOM 7568 C CB . ASN B 2 78 ? 145.905 512.606 59.630 1.00 28.24 ? 107 ASN B CB 1 ATOM 7569 C CG . ASN B 2 78 ? 146.952 513.514 60.194 1.00 66.40 ? 107 ASN B CG 1 ATOM 7570 O OD1 . ASN B 2 78 ? 147.468 513.298 61.292 1.00 72.04 ? 107 ASN B OD1 1 ATOM 7571 N ND2 . ASN B 2 78 ? 147.245 514.584 59.482 1.00 54.66 ? 107 ASN B ND2 1 ATOM 7572 N N . SER B 2 79 ? 143.043 513.028 62.016 1.00 31.25 ? 108 SER B N 1 ATOM 7573 C CA . SER B 2 79 ? 142.129 514.033 62.515 1.00 30.29 ? 108 SER B CA 1 ATOM 7574 C C . SER B 2 79 ? 141.972 514.075 64.023 1.00 34.72 ? 108 SER B C 1 ATOM 7575 O O . SER B 2 79 ? 141.244 514.931 64.523 1.00 34.37 ? 108 SER B O 1 ATOM 7576 C CB . SER B 2 79 ? 140.750 513.788 61.914 1.00 32.45 ? 108 SER B CB 1 ATOM 7577 O OG . SER B 2 79 ? 140.134 512.650 62.506 1.00 36.49 ? 108 SER B OG 1 ATOM 7578 N N . GLY B 2 80 ? 142.483 513.105 64.739 1.00 32.77 ? 109 GLY B N 1 ATOM 7579 C CA . GLY B 2 80 ? 142.169 513.112 66.164 1.00 34.81 ? 109 GLY B CA 1 ATOM 7580 C C . GLY B 2 80 ? 140.905 512.365 66.567 1.00 41.14 ? 109 GLY B C 1 ATOM 7581 O O . GLY B 2 80 ? 140.758 512.040 67.750 1.00 42.25 ? 109 GLY B O 1 ATOM 7582 N N . THR B 2 81 ? 139.993 512.031 65.610 1.00 36.09 ? 110 THR B N 1 ATOM 7583 C CA . THR B 2 81 ? 138.900 511.109 65.893 1.00 33.95 ? 110 THR B CA 1 ATOM 7584 C C . THR B 2 81 ? 139.485 509.769 65.431 1.00 37.24 ? 110 THR B C 1 ATOM 7585 O O . THR B 2 81 ? 140.092 509.698 64.355 1.00 35.83 ? 110 THR B O 1 ATOM 7586 C CB . THR B 2 81 ? 137.638 511.388 65.095 1.00 29.08 ? 110 THR B CB 1 ATOM 7587 O OG1 . THR B 2 81 ? 137.071 512.638 65.463 1.00 17.65 ? 110 THR B OG1 1 ATOM 7588 C CG2 . THR B 2 81 ? 136.607 510.292 65.281 1.00 24.41 ? 110 THR B CG2 1 ATOM 7589 N N . VAL B 2 82 ? 139.360 508.739 66.265 1.00 35.74 ? 111 VAL B N 1 ATOM 7590 C CA . VAL B 2 82 ? 139.814 507.370 65.985 1.00 36.20 ? 111 VAL B CA 1 ATOM 7591 C C . VAL B 2 82 ? 138.547 506.609 65.727 1.00 40.82 ? 111 VAL B C 1 ATOM 7592 O O . VAL B 2 82 ? 137.725 506.465 66.631 1.00 42.46 ? 111 VAL B O 1 ATOM 7593 C CB . VAL B 2 82 ? 140.598 506.739 67.159 1.00 40.38 ? 111 VAL B CB 1 ATOM 7594 C CG1 . VAL B 2 82 ? 140.895 505.259 66.886 1.00 40.95 ? 111 VAL B CG1 1 ATOM 7595 C CG2 . VAL B 2 82 ? 141.879 507.507 67.448 1.00 39.89 ? 111 VAL B CG2 1 ATOM 7596 N N . CYS B 2 83 ? 138.345 506.182 64.497 1.00 36.68 ? 112 CYS B N 1 ATOM 7597 C CA . CYS B 2 83 ? 137.120 505.491 64.136 1.00 36.51 ? 112 CYS B CA 1 ATOM 7598 C C . CYS B 2 83 ? 137.229 503.993 64.275 1.00 43.69 ? 112 CYS B C 1 ATOM 7599 O O . CYS B 2 83 ? 138.230 503.407 63.871 1.00 44.03 ? 112 CYS B O 1 ATOM 7600 C CB . CYS B 2 83 ? 136.682 505.885 62.734 1.00 35.50 ? 112 CYS B CB 1 ATOM 7601 S SG . CYS B 2 83 ? 136.197 507.624 62.577 1.00 38.37 ? 112 CYS B SG 1 ATOM 7602 N N . GLU B 2 84 ? 136.200 503.371 64.828 1.00 41.07 ? 113 GLU B N 1 ATOM 7603 C CA . GLU B 2 84 ? 136.190 501.931 64.965 1.00 42.01 ? 113 GLU B CA 1 ATOM 7604 C C . GLU B 2 84 ? 135.558 501.325 63.718 1.00 48.15 ? 113 GLU B C 1 ATOM 7605 O O . GLU B 2 84 ? 134.722 501.961 63.051 1.00 48.68 ? 113 GLU B O 1 ATOM 7606 C CB . GLU B 2 84 ? 135.412 501.497 66.226 1.00 43.95 ? 113 GLU B CB 1 ATOM 7607 C CG . GLU B 2 84 ? 136.097 501.825 67.556 1.00 62.96 ? 113 GLU B CG 1 ATOM 7608 C CD . GLU B 2 84 ? 137.479 501.235 67.779 1.00 98.49 ? 113 GLU B CD 1 ATOM 7609 O OE1 . GLU B 2 84 ? 137.635 500.002 67.625 1.00 104.87 ? 113 GLU B OE1 1 ATOM 7610 O OE2 . GLU B 2 84 ? 138.404 502.006 68.127 1.00 96.93 ? 113 GLU B OE2 1 ATOM 7611 N N . ASN B 2 85 ? 135.943 500.077 63.407 1.00 43.61 ? 114 ASN B N 1 ATOM 7612 C CA . ASN B 2 85 ? 135.345 499.360 62.298 1.00 42.33 ? 114 ASN B CA 1 ATOM 7613 C C . ASN B 2 85 ? 133.935 498.908 62.692 1.00 46.71 ? 114 ASN B C 1 ATOM 7614 O O . ASN B 2 85 ? 133.769 498.125 63.616 1.00 47.89 ? 114 ASN B O 1 ATOM 7615 C CB . ASN B 2 85 ? 136.192 498.179 61.888 1.00 39.45 ? 114 ASN B CB 1 ATOM 7616 C CG . ASN B 2 85 ? 135.799 497.653 60.543 1.00 44.71 ? 114 ASN B CG 1 ATOM 7617 O OD1 . ASN B 2 85 ? 134.637 497.333 60.277 1.00 39.53 ? 114 ASN B OD1 1 ATOM 7618 N ND2 . ASN B 2 85 ? 136.758 497.637 59.645 1.00 31.99 ? 114 ASN B ND2 1 ATOM 7619 N N . THR B 2 86 ? 132.931 499.424 62.012 1.00 41.99 ? 115 THR B N 1 ATOM 7620 C CA . THR B 2 86 ? 131.548 499.114 62.324 1.00 41.29 ? 115 THR B CA 1 ATOM 7621 C C . THR B 2 86 ? 130.917 498.442 61.124 1.00 46.57 ? 115 THR B C 1 ATOM 7622 O O . THR B 2 86 ? 129.688 498.476 60.978 1.00 46.97 ? 115 THR B O 1 ATOM 7623 C CB . THR B 2 86 ? 130.768 500.414 62.653 1.00 46.20 ? 115 THR B CB 1 ATOM 7624 O OG1 . THR B 2 86 ? 130.547 501.169 61.457 1.00 48.64 ? 115 THR B OG1 1 ATOM 7625 C CG2 . THR B 2 86 ? 131.448 501.270 63.691 1.00 43.67 ? 115 THR B CG2 1 ATOM 7626 N N . CYS B 2 87 ? 131.730 497.842 60.249 1.00 42.44 ? 116 CYS B N 1 ATOM 7627 C CA . CYS B 2 87 ? 131.197 497.277 59.018 1.00 41.56 ? 116 CYS B CA 1 ATOM 7628 C C . CYS B 2 87 ? 130.206 496.115 59.192 1.00 47.09 ? 116 CYS B C 1 ATOM 7629 O O . CYS B 2 87 ? 129.292 496.011 58.373 1.00 46.56 ? 116 CYS B O 1 ATOM 7630 C CB . CYS B 2 87 ? 132.325 496.920 58.064 1.00 40.86 ? 116 CYS B CB 1 ATOM 7631 S SG . CYS B 2 87 ? 133.227 498.364 57.452 1.00 43.33 ? 116 CYS B SG 1 ATOM 7632 N N . ARG B 2 88 ? 130.309 495.312 60.268 1.00 46.05 ? 117 ARG B N 1 ATOM 7633 C CA . ARG B 2 88 ? 129.320 494.247 60.510 1.00 52.19 ? 117 ARG B CA 1 ATOM 7634 C C . ARG B 2 88 ? 127.937 494.763 60.984 1.00 75.76 ? 117 ARG B C 1 ATOM 7635 O O . ARG B 2 88 ? 126.926 494.081 60.717 1.00 80.54 ? 117 ARG B O 1 ATOM 7636 C CB . ARG B 2 88 ? 129.862 493.184 61.462 1.00 53.35 ? 117 ARG B CB 1 ATOM 7637 C CG . ARG B 2 88 ? 130.214 493.682 62.849 1.00 67.61 ? 117 ARG B CG 1 ATOM 7638 C CD . ARG B 2 88 ? 131.022 492.628 63.585 1.00 84.95 ? 117 ARG B CD 1 ATOM 7639 N NE . ARG B 2 88 ? 131.717 493.183 64.751 1.00 98.46 ? 117 ARG B NE 1 ATOM 7640 C CZ . ARG B 2 88 ? 132.680 492.564 65.433 1.00 110.55 ? 117 ARG B CZ 1 ATOM 7641 N NH1 . ARG B 2 88 ? 133.088 491.350 65.073 1.00 92.23 ? 117 ARG B NH1 1 ATOM 7642 N NH2 . ARG B 2 88 ? 133.248 493.157 66.476 1.00 98.33 ? 117 ARG B NH2 1 ATOM 7643 O OXT . ARG B 2 88 ? 127.867 495.834 61.629 1.00 97.48 ? 117 ARG B OXT 1 HETATM 7644 C C1 . NAG C 3 . ? 138.314 563.801 70.762 1.00 28.09 ? 1001 NAG A C1 1 HETATM 7645 C C2 . NAG C 3 . ? 138.806 562.710 69.803 1.00 26.33 ? 1001 NAG A C2 1 HETATM 7646 C C3 . NAG C 3 . ? 139.957 563.259 68.954 1.00 28.33 ? 1001 NAG A C3 1 HETATM 7647 C C4 . NAG C 3 . ? 139.594 564.576 68.265 1.00 29.51 ? 1001 NAG A C4 1 HETATM 7648 C C5 . NAG C 3 . ? 139.161 565.595 69.320 1.00 27.85 ? 1001 NAG A C5 1 HETATM 7649 C C6 . NAG C 3 . ? 138.657 566.895 68.744 1.00 27.80 ? 1001 NAG A C6 1 HETATM 7650 C C7 . NAG C 3 . ? 138.559 560.489 70.927 1.00 24.63 ? 1001 NAG A C7 1 HETATM 7651 C C8 . NAG C 3 . ? 139.276 559.469 71.761 1.00 20.99 ? 1001 NAG A C8 1 HETATM 7652 N N2 . NAG C 3 . ? 139.276 561.595 70.611 1.00 26.59 ? 1001 NAG A N2 1 HETATM 7653 O O3 . NAG C 3 . ? 140.362 562.288 68.004 1.00 28.99 ? 1001 NAG A O3 1 HETATM 7654 O O4 . NAG C 3 . ? 140.715 565.066 67.517 1.00 30.86 ? 1001 NAG A O4 1 HETATM 7655 O O5 . NAG C 3 . ? 138.075 565.061 70.100 1.00 27.79 ? 1001 NAG A O5 1 HETATM 7656 O O6 . NAG C 3 . ? 137.444 566.708 68.019 1.00 28.73 ? 1001 NAG A O6 1 HETATM 7657 O O7 . NAG C 3 . ? 137.395 560.327 70.565 1.00 23.80 ? 1001 NAG A O7 1 HETATM 7658 C C1 . NAG D 3 . ? 140.532 565.519 66.165 1.00 39.52 ? 1002 NAG A C1 1 HETATM 7659 C C2 . NAG D 3 . ? 141.701 566.430 65.769 1.00 42.53 ? 1002 NAG A C2 1 HETATM 7660 C C3 . NAG D 3 . ? 141.601 566.823 64.291 1.00 49.59 ? 1002 NAG A C3 1 HETATM 7661 C C4 . NAG D 3 . ? 141.421 565.599 63.401 1.00 53.44 ? 1002 NAG A C4 1 HETATM 7662 C C5 . NAG D 3 . ? 140.208 564.793 63.877 1.00 52.88 ? 1002 NAG A C5 1 HETATM 7663 C C6 . NAG D 3 . ? 139.969 563.512 63.095 1.00 54.30 ? 1002 NAG A C6 1 HETATM 7664 C C7 . NAG D 3 . ? 142.347 567.750 67.762 1.00 34.63 ? 1002 NAG A C7 1 HETATM 7665 C C8 . NAG D 3 . ? 142.144 569.049 68.484 1.00 34.23 ? 1002 NAG A C8 1 HETATM 7666 N N2 . NAG D 3 . ? 141.698 567.625 66.598 1.00 37.57 ? 1002 NAG A N2 1 HETATM 7667 O O3 . NAG D 3 . ? 142.755 567.550 63.878 1.00 51.81 ? 1002 NAG A O3 1 HETATM 7668 O O4 . NAG D 3 . ? 141.321 566.011 62.034 1.00 54.63 ? 1002 NAG A O4 1 HETATM 7669 O O5 . NAG D 3 . ? 140.384 564.416 65.260 1.00 46.59 ? 1002 NAG A O5 1 HETATM 7670 O O6 . NAG D 3 . ? 138.654 562.991 63.297 1.00 53.01 ? 1002 NAG A O6 1 HETATM 7671 O O7 . NAG D 3 . ? 143.051 566.856 68.220 1.00 33.53 ? 1002 NAG A O7 1 HETATM 7672 C C . FMT E 4 . ? 134.009 532.923 46.274 1.00 41.89 ? 1003 FMT A C 1 HETATM 7673 O O1 . FMT E 4 . ? 135.095 532.701 46.759 1.00 41.68 ? 1003 FMT A O1 1 HETATM 7674 O O2 . FMT E 4 . ? 134.008 533.189 44.936 1.00 44.21 ? 1003 FMT A O2 1 HETATM 7675 H H . FMT E 4 . ? 133.063 532.908 46.813 1.00 41.89 ? 1003 FMT A H 1 HETATM 7676 H HO2 . FMT E 4 . ? 134.924 533.153 44.553 1.00 44.25 ? 1003 FMT A HO2 1 HETATM 7677 C C . ACT F 5 . ? 122.580 563.886 91.046 1.00 38.43 ? 1004 ACT A C 1 HETATM 7678 O O . ACT F 5 . ? 122.031 564.654 90.237 1.00 40.61 ? 1004 ACT A O 1 HETATM 7679 O OXT . ACT F 5 . ? 122.441 563.917 92.315 1.00 37.11 ? 1004 ACT A OXT 1 HETATM 7680 C CH3 . ACT F 5 . ? 123.462 562.795 90.396 1.00 36.01 ? 1004 ACT A CH3 1 HETATM 7681 H H1 . ACT F 5 . ? 124.014 562.234 91.149 1.00 35.95 ? 1004 ACT A H1 1 HETATM 7682 H H2 . ACT F 5 . ? 124.188 563.220 89.708 1.00 35.43 ? 1004 ACT A H2 1 HETATM 7683 H H3 . ACT F 5 . ? 122.862 562.087 89.826 1.00 35.61 ? 1004 ACT A H3 1 HETATM 7684 O O9 . NBV G 6 . ? 108.404 529.416 72.073 1.00 34.33 ? 1005 NBV A O9 1 HETATM 7685 C C12 . NBV G 6 . ? 107.627 529.488 70.900 1.00 32.61 ? 1005 NBV A C12 1 HETATM 7686 C C11 . NBV G 6 . ? 107.791 530.820 70.187 1.00 36.27 ? 1005 NBV A C11 1 HETATM 7687 C C10 . NBV G 6 . ? 109.159 530.874 69.506 1.00 37.31 ? 1005 NBV A C10 1 HETATM 7688 O O1 . NBV G 6 . ? 109.187 529.934 68.442 1.00 34.58 ? 1005 NBV A O1 1 HETATM 7689 C C9 . NBV G 6 . ? 109.441 532.252 68.935 1.00 39.57 ? 1005 NBV A C9 1 HETATM 7690 O O8 . NBV G 6 . ? 110.720 532.271 68.312 1.00 41.32 ? 1005 NBV A O8 1 HETATM 7691 C C8 . NBV G 6 . ? 109.373 533.282 70.049 1.00 39.96 ? 1005 NBV A C8 1 HETATM 7692 O O7 . NBV G 6 . ? 109.722 534.578 69.552 1.00 38.36 ? 1005 NBV A O7 1 HETATM 7693 N N1 . NBV G 6 . ? 107.488 531.956 71.095 1.00 39.56 ? 1005 NBV A N1 1 HETATM 7694 C C7 . NBV G 6 . ? 107.988 533.281 70.682 1.00 39.39 ? 1005 NBV A C7 1 HETATM 7695 C C13 . NBV G 6 . ? 106.035 532.054 71.334 1.00 44.26 ? 1005 NBV A C13 1 HETATM 7696 C C14 . NBV G 6 . ? 105.565 531.741 72.739 1.00 45.97 ? 1005 NBV A C14 1 HETATM 7697 C C15 . NBV G 6 . ? 104.064 531.465 72.822 1.00 43.76 ? 1005 NBV A C15 1 HETATM 7698 C C16 . NBV G 6 . ? 103.235 532.551 72.141 1.00 43.30 ? 1005 NBV A C16 1 HETATM 7699 H H9 . NBV G 6 . ? 108.923 528.573 72.012 1.00 34.08 ? 1005 NBV A H9 1 HETATM 7700 H H121 . NBV G 6 . ? 107.831 528.660 70.225 1.00 32.76 ? 1005 NBV A H121 1 HETATM 7701 H H122 . NBV G 6 . ? 106.605 529.325 71.238 1.00 32.70 ? 1005 NBV A H122 1 HETATM 7702 H H11 . NBV G 6 . ? 107.077 530.783 69.365 1.00 36.65 ? 1005 NBV A H11 1 HETATM 7703 H H10 . NBV G 6 . ? 109.936 530.627 70.226 1.00 37.84 ? 1005 NBV A H10 1 HETATM 7704 H H1 . NBV G 6 . ? 109.930 529.305 68.632 1.00 33.61 ? 1005 NBV A H1 1 HETATM 7705 H HA . NBV G 6 . ? 108.686 532.499 68.193 1.00 39.84 ? 1005 NBV A HA 1 HETATM 7706 H H8 . NBV G 6 . ? 110.622 532.813 67.485 1.00 41.27 ? 1005 NBV A H8 1 HETATM 7707 H HB . NBV G 6 . ? 110.133 532.972 70.761 1.00 40.56 ? 1005 NBV A HB 1 HETATM 7708 H H7 . NBV G 6 . ? 108.924 535.168 69.555 1.00 37.88 ? 1005 NBV A H7 1 HETATM 7709 H H7C1 . NBV G 6 . ? 107.993 533.899 71.578 1.00 38.91 ? 1005 NBV A H7C1 1 HETATM 7710 H H7C2 . NBV G 6 . ? 107.313 533.797 70.000 1.00 39.61 ? 1005 NBV A H7C2 1 HETATM 7711 H H131 . NBV G 6 . ? 105.628 533.024 71.056 1.00 44.42 ? 1005 NBV A H131 1 HETATM 7712 H H132 . NBV G 6 . ? 105.496 531.374 70.677 1.00 44.56 ? 1005 NBV A H132 1 HETATM 7713 H H141 . NBV G 6 . ? 106.146 530.926 73.169 1.00 45.90 ? 1005 NBV A H141 1 HETATM 7714 H H142 . NBV G 6 . ? 105.791 532.605 73.359 1.00 46.73 ? 1005 NBV A H142 1 HETATM 7715 H H151 . NBV G 6 . ? 103.833 530.498 72.378 1.00 43.57 ? 1005 NBV A H151 1 HETATM 7716 H H161 . NBV G 6 . ? 103.639 533.548 72.312 1.00 43.30 ? 1005 NBV A H161 1 HETATM 7717 H H162 . NBV G 6 . ? 103.196 532.417 71.061 1.00 43.27 ? 1005 NBV A H162 1 HETATM 7718 H H163 . NBV G 6 . ? 102.207 532.575 72.499 1.00 43.59 ? 1005 NBV A H163 1 HETATM 7719 C C3 . P6G H 7 . ? 118.340 552.906 97.254 1.00 52.24 ? 1006 P6G A C3 1 HETATM 7720 O O4 . P6G H 7 . ? 117.652 551.659 97.365 1.00 50.58 ? 1006 P6G A O4 1 HETATM 7721 C C5 . P6G H 7 . ? 118.495 550.516 97.492 1.00 45.88 ? 1006 P6G A C5 1 HETATM 7722 C C6 . P6G H 7 . ? 117.663 549.278 97.355 1.00 43.82 ? 1006 P6G A C6 1 HETATM 7723 O O7 . P6G H 7 . ? 117.647 548.821 96.014 1.00 44.21 ? 1006 P6G A O7 1 HETATM 7724 C C8 . P6G H 7 . ? 118.570 547.785 95.723 1.00 39.84 ? 1006 P6G A C8 1 HETATM 7725 C C9 . P6G H 7 . ? 118.774 547.721 94.253 1.00 40.78 ? 1006 P6G A C9 1 HETATM 7726 O O10 . P6G H 7 . ? 119.301 548.958 93.797 1.00 43.71 ? 1006 P6G A O10 1 HETATM 7727 C C11 . P6G H 7 . ? 119.587 549.001 92.403 1.00 45.15 ? 1006 P6G A C11 1 HETATM 7728 C C12 . P6G H 7 . ? 119.515 550.413 91.909 1.00 48.93 ? 1006 P6G A C12 1 HETATM 7729 O O13 . P6G H 7 . ? 120.422 551.225 92.641 1.00 53.44 ? 1006 P6G A O13 1 HETATM 7730 C C14 . P6G H 7 . ? 120.143 552.622 92.591 1.00 57.32 ? 1006 P6G A C14 1 HETATM 7731 C C15 . P6G H 7 . ? 119.685 553.109 93.931 1.00 57.90 ? 1006 P6G A C15 1 HETATM 7732 O O16 . P6G H 7 . ? 119.011 554.354 93.799 1.00 57.00 ? 1006 P6G A O16 1 HETATM 7733 H H51 . P6G H 7 . ? 119.001 550.514 98.457 1.00 45.71 ? 1006 P6G A H51 1 HETATM 7734 H H52 . P6G H 7 . ? 119.273 550.512 96.731 1.00 45.45 ? 1006 P6G A H52 1 HETATM 7735 H H61 . P6G H 7 . ? 116.647 549.499 97.678 1.00 43.65 ? 1006 P6G A H61 1 HETATM 7736 H H62 . P6G H 7 . ? 118.017 548.485 98.006 1.00 43.35 ? 1006 P6G A H62 1 HETATM 7737 H H81 . P6G H 7 . ? 118.217 546.828 96.104 1.00 39.44 ? 1006 P6G A H81 1 HETATM 7738 H H82 . P6G H 7 . ? 119.528 547.972 96.204 1.00 39.84 ? 1006 P6G A H82 1 HETATM 7739 H H91 . P6G H 7 . ? 117.822 547.512 93.768 1.00 41.10 ? 1006 P6G A H91 1 HETATM 7740 H H92 . P6G H 7 . ? 119.441 546.899 93.997 1.00 40.89 ? 1006 P6G A H92 1 HETATM 7741 H H111 . P6G H 7 . ? 118.878 548.392 91.847 1.00 45.12 ? 1006 P6G A H111 1 HETATM 7742 H H112 . P6G H 7 . ? 120.575 548.592 92.201 1.00 44.81 ? 1006 P6G A H112 1 HETATM 7743 H H121 . P6G H 7 . ? 118.495 550.777 92.021 1.00 48.99 ? 1006 P6G A H121 1 HETATM 7744 H H122 . P6G H 7 . ? 119.731 550.455 90.842 1.00 48.80 ? 1006 P6G A H122 1 HETATM 7745 H H141 . P6G H 7 . ? 119.413 552.865 91.820 1.00 57.44 ? 1006 P6G A H141 1 HETATM 7746 H H142 . P6G H 7 . ? 121.049 553.165 92.325 1.00 57.91 ? 1006 P6G A H142 1 HETATM 7747 H H151 . P6G H 7 . ? 120.545 553.225 94.590 1.00 57.94 ? 1006 P6G A H151 1 HETATM 7748 H H152 . P6G H 7 . ? 119.050 552.357 94.395 1.00 58.15 ? 1006 P6G A H152 1 HETATM 7749 O O1 . P6G I 7 . ? 116.917 553.277 46.047 1.00 74.34 ? 1007 P6G A O1 1 HETATM 7750 C C2 . P6G I 7 . ? 115.985 553.154 47.126 1.00 76.30 ? 1007 P6G A C2 1 HETATM 7751 C C3 . P6G I 7 . ? 115.596 551.715 47.401 1.00 77.02 ? 1007 P6G A C3 1 HETATM 7752 O O4 . P6G I 7 . ? 114.566 551.633 48.389 1.00 77.16 ? 1007 P6G A O4 1 HETATM 7753 C C5 . P6G I 7 . ? 114.987 551.849 49.737 1.00 77.78 ? 1007 P6G A C5 1 HETATM 7754 C C6 . P6G I 7 . ? 113.880 552.526 50.492 1.00 79.79 ? 1007 P6G A C6 1 HETATM 7755 O O7 . P6G I 7 . ? 114.242 552.981 51.805 1.00 80.29 ? 1007 P6G A O7 1 HETATM 7756 C C8 . P6G I 7 . ? 115.156 554.077 51.943 1.00 80.43 ? 1007 P6G A C8 1 HETATM 7757 C C9 . P6G I 7 . ? 114.873 555.260 51.070 1.00 82.24 ? 1007 P6G A C9 1 HETATM 7758 O O10 . P6G I 7 . ? 115.576 555.119 49.836 1.00 84.19 ? 1007 P6G A O10 1 HETATM 7759 C C11 . P6G I 7 . ? 116.427 556.211 49.486 1.00 84.09 ? 1007 P6G A C11 1 HETATM 7760 C C12 . P6G I 7 . ? 117.782 556.082 50.131 1.00 82.06 ? 1007 P6G A C12 1 HETATM 7761 O O13 . P6G I 7 . ? 118.737 555.625 49.173 1.00 80.00 ? 1007 P6G A O13 1 HETATM 7762 C C14 . P6G I 7 . ? 119.521 556.625 48.517 1.00 75.59 ? 1007 P6G A C14 1 HETATM 7763 C C15 . P6G I 7 . ? 119.879 556.238 47.102 1.00 68.57 ? 1007 P6G A C15 1 HETATM 7764 O O16 . P6G I 7 . ? 121.203 556.685 46.844 1.00 61.49 ? 1007 P6G A O16 1 HETATM 7765 C C17 . P6G I 7 . ? 121.590 556.705 45.477 1.00 56.82 ? 1007 P6G A C17 1 HETATM 7766 C C18 . P6G I 7 . ? 123.018 557.164 45.396 1.00 51.45 ? 1007 P6G A C18 1 HETATM 7767 O O19 . P6G I 7 . ? 123.354 557.723 44.141 1.00 50.22 ? 1007 P6G A O19 1 HETATM 7768 H H1 . P6G I 7 . ? 117.226 554.221 46.016 1.00 73.88 ? 1007 P6G A H1 1 HETATM 7769 H H21 . P6G I 7 . ? 115.116 553.795 46.983 1.00 76.49 ? 1007 P6G A H21 1 HETATM 7770 H H22 . P6G I 7 . ? 116.544 553.571 47.962 1.00 76.44 ? 1007 P6G A H22 1 HETATM 7771 H H31 . P6G I 7 . ? 116.471 551.166 47.742 1.00 77.09 ? 1007 P6G A H31 1 HETATM 7772 H H32 . P6G I 7 . ? 115.276 551.227 46.482 1.00 77.05 ? 1007 P6G A H32 1 HETATM 7773 H H51 . P6G I 7 . ? 115.884 552.462 49.778 1.00 77.64 ? 1007 P6G A H51 1 HETATM 7774 H H52 . P6G I 7 . ? 115.233 550.898 50.206 1.00 77.38 ? 1007 P6G A H52 1 HETATM 7775 H H61 . P6G I 7 . ? 113.082 551.792 50.590 1.00 80.02 ? 1007 P6G A H61 1 HETATM 7776 H H62 . P6G I 7 . ? 113.448 553.322 49.889 1.00 80.04 ? 1007 P6G A H62 1 HETATM 7777 H H81 . P6G I 7 . ? 116.179 553.742 51.785 1.00 80.30 ? 1007 P6G A H81 1 HETATM 7778 H H82 . P6G I 7 . ? 115.140 554.427 52.974 1.00 80.07 ? 1007 P6G A H82 1 HETATM 7779 H H91 . P6G I 7 . ? 115.169 556.166 51.598 1.00 82.10 ? 1007 P6G A H91 1 HETATM 7780 H H92 . P6G I 7 . ? 113.804 555.358 50.888 1.00 82.32 ? 1007 P6G A H92 1 HETATM 7781 H H111 . P6G I 7 . ? 115.974 557.169 49.734 1.00 84.03 ? 1007 P6G A H111 1 HETATM 7782 H H112 . P6G I 7 . ? 116.559 556.220 48.404 1.00 84.42 ? 1007 P6G A H112 1 HETATM 7783 H H121 . P6G I 7 . ? 117.723 555.369 50.953 1.00 81.87 ? 1007 P6G A H121 1 HETATM 7784 H H122 . P6G I 7 . ? 118.087 557.022 50.588 1.00 81.90 ? 1007 P6G A H122 1 HETATM 7785 H H141 . P6G I 7 . ? 120.442 556.770 49.077 1.00 75.66 ? 1007 P6G A H141 1 HETATM 7786 H H142 . P6G I 7 . ? 119.019 557.592 48.503 1.00 75.78 ? 1007 P6G A H142 1 HETATM 7787 H H151 . P6G I 7 . ? 119.176 556.687 46.403 1.00 68.22 ? 1007 P6G A H151 1 HETATM 7788 H H152 . P6G I 7 . ? 119.813 555.161 46.960 1.00 68.75 ? 1007 P6G A H152 1 HETATM 7789 H H171 . P6G I 7 . ? 120.942 557.358 44.894 1.00 57.01 ? 1007 P6G A H171 1 HETATM 7790 H H172 . P6G I 7 . ? 121.484 555.713 45.040 1.00 56.78 ? 1007 P6G A H172 1 HETATM 7791 H H181 . P6G I 7 . ? 123.698 556.322 45.502 1.00 50.99 ? 1007 P6G A H181 1 HETATM 7792 H H182 . P6G I 7 . ? 123.251 557.854 46.202 1.00 50.76 ? 1007 P6G A H182 1 HETATM 7793 H H19 . P6G I 7 . ? 124.259 558.122 44.222 1.00 49.85 ? 1007 P6G A H19 1 HETATM 7794 CA CA . CA J 8 . ? 147.207 517.996 44.163 1.00 23.60 2 201 CA B CA 1 HETATM 7795 CA CA . CA K 8 . ? 134.916 511.636 57.995 1.00 24.40 2 202 CA B CA 1 HETATM 7796 O O . HOH L 9 . ? 123.594 553.815 54.649 1.00 25.64 ? 1101 HOH A O 1 HETATM 7797 O O . HOH L 9 . ? 119.183 553.210 48.542 1.00 33.74 ? 1102 HOH A O 1 HETATM 7798 O O . HOH L 9 . ? 110.386 566.528 78.852 1.00 31.80 ? 1103 HOH A O 1 HETATM 7799 O O . HOH L 9 . ? 113.900 541.311 69.772 1.00 9.73 ? 1104 HOH A O 1 HETATM 7800 O O . HOH L 9 . ? 108.737 530.489 74.521 1.00 17.89 ? 1105 HOH A O 1 HETATM 7801 O O . HOH L 9 . ? 114.010 526.843 56.389 1.00 12.32 ? 1106 HOH A O 1 HETATM 7802 O O . HOH L 9 . ? 113.812 537.295 43.708 1.00 16.42 ? 1107 HOH A O 1 HETATM 7803 O O . HOH L 9 . ? 115.095 546.354 38.949 1.00 32.03 ? 1108 HOH A O 1 HETATM 7804 O O . HOH L 9 . ? 96.974 540.542 78.106 1.00 19.27 ? 1109 HOH A O 1 HETATM 7805 O O . HOH L 9 . ? 105.029 539.556 65.820 1.00 26.30 ? 1110 HOH A O 1 HETATM 7806 O O . HOH L 9 . ? 104.798 556.396 89.651 1.00 30.43 ? 1111 HOH A O 1 HETATM 7807 O O . HOH L 9 . ? 126.222 534.130 74.769 1.00 25.24 ? 1112 HOH A O 1 HETATM 7808 O O . HOH L 9 . ? 117.820 553.476 63.419 1.00 23.39 ? 1113 HOH A O 1 HETATM 7809 O O . HOH L 9 . ? 98.914 559.669 71.343 1.00 29.51 ? 1114 HOH A O 1 HETATM 7810 O O . HOH L 9 . ? 136.110 537.902 47.854 1.00 28.98 ? 1115 HOH A O 1 HETATM 7811 O O . HOH L 9 . ? 112.347 522.811 67.859 1.00 35.85 ? 1116 HOH A O 1 HETATM 7812 O O . HOH L 9 . ? 144.447 541.365 69.942 1.00 23.48 ? 1117 HOH A O 1 HETATM 7813 O O . HOH L 9 . ? 128.733 534.465 73.433 1.00 14.96 ? 1118 HOH A O 1 HETATM 7814 O O . HOH L 9 . ? 123.753 522.921 81.281 1.00 34.46 ? 1119 HOH A O 1 HETATM 7815 O O . HOH L 9 . ? 119.634 540.901 76.556 1.00 25.59 ? 1120 HOH A O 1 HETATM 7816 O O . HOH L 9 . ? 115.236 521.566 78.866 1.00 29.86 ? 1121 HOH A O 1 HETATM 7817 O O . HOH L 9 . ? 111.220 573.243 81.102 1.00 21.72 ? 1122 HOH A O 1 HETATM 7818 O O . HOH L 9 . ? 114.262 552.553 79.023 1.00 25.53 ? 1123 HOH A O 1 HETATM 7819 O O . HOH L 9 . ? 107.614 535.114 80.151 1.00 15.95 ? 1124 HOH A O 1 HETATM 7820 O O . HOH L 9 . ? 104.337 562.016 92.693 1.00 18.18 ? 1125 HOH A O 1 HETATM 7821 O O . HOH L 9 . ? 124.167 548.502 73.718 1.00 22.47 ? 1126 HOH A O 1 HETATM 7822 O O . HOH L 9 . ? 133.302 557.129 59.447 1.00 28.38 ? 1127 HOH A O 1 HETATM 7823 O O . HOH L 9 . ? 105.596 538.406 69.180 1.00 22.03 ? 1128 HOH A O 1 HETATM 7824 O O . HOH L 9 . ? 133.417 518.728 67.479 1.00 23.36 ? 1129 HOH A O 1 HETATM 7825 O O . HOH L 9 . ? 118.866 558.270 93.299 1.00 25.39 ? 1130 HOH A O 1 HETATM 7826 O O . HOH L 9 . ? 131.397 558.213 47.554 1.00 30.02 ? 1131 HOH A O 1 HETATM 7827 O O . HOH L 9 . ? 128.542 535.310 54.636 1.00 14.55 ? 1132 HOH A O 1 HETATM 7828 O O . HOH L 9 . ? 102.467 549.842 60.380 1.00 30.91 ? 1133 HOH A O 1 HETATM 7829 O O . HOH L 9 . ? 157.963 531.219 37.631 1.00 26.40 ? 1134 HOH A O 1 HETATM 7830 O O . HOH L 9 . ? 101.915 552.147 70.899 1.00 30.49 ? 1135 HOH A O 1 HETATM 7831 O O . HOH L 9 . ? 150.852 533.890 58.737 1.00 20.32 ? 1136 HOH A O 1 HETATM 7832 O O . HOH L 9 . ? 150.248 525.947 61.045 1.00 32.41 ? 1137 HOH A O 1 HETATM 7833 O O . HOH L 9 . ? 105.684 535.436 72.143 1.00 29.47 ? 1138 HOH A O 1 HETATM 7834 O O . HOH L 9 . ? 123.876 577.487 78.087 1.00 40.40 ? 1139 HOH A O 1 HETATM 7835 O O . HOH L 9 . ? 154.771 536.486 64.110 1.00 16.79 ? 1140 HOH A O 1 HETATM 7836 O O . HOH L 9 . ? 131.338 534.822 74.493 1.00 12.11 ? 1141 HOH A O 1 HETATM 7837 O O . HOH L 9 . ? 110.717 534.194 66.374 1.00 17.32 ? 1142 HOH A O 1 HETATM 7838 O O . HOH L 9 . ? 97.984 562.477 84.156 1.00 33.77 ? 1143 HOH A O 1 HETATM 7839 O O . HOH L 9 . ? 100.319 553.114 84.454 1.00 19.45 ? 1144 HOH A O 1 HETATM 7840 O O . HOH L 9 . ? 110.993 524.054 59.232 1.00 18.43 ? 1145 HOH A O 1 HETATM 7841 O O . HOH L 9 . ? 137.551 524.495 55.815 1.00 31.78 ? 1146 HOH A O 1 HETATM 7842 O O . HOH L 9 . ? 139.506 550.886 46.409 1.00 41.60 ? 1147 HOH A O 1 HETATM 7843 O O . HOH L 9 . ? 143.527 525.492 65.022 1.00 41.39 ? 1148 HOH A O 1 HETATM 7844 O O . HOH L 9 . ? 106.485 527.016 56.013 1.00 31.65 ? 1149 HOH A O 1 HETATM 7845 O O . HOH L 9 . ? 148.974 536.871 67.583 1.00 30.44 ? 1150 HOH A O 1 HETATM 7846 O O . HOH L 9 . ? 132.499 559.572 60.864 1.00 29.37 ? 1151 HOH A O 1 HETATM 7847 O O . HOH L 9 . ? 112.013 517.826 57.732 1.00 19.62 ? 1152 HOH A O 1 HETATM 7848 O O . HOH L 9 . ? 119.312 537.173 59.911 1.00 35.04 ? 1153 HOH A O 1 HETATM 7849 O O . HOH L 9 . ? 124.563 541.721 70.104 1.00 18.14 ? 1154 HOH A O 1 HETATM 7850 O O . HOH L 9 . ? 141.078 527.439 51.949 1.00 28.87 ? 1155 HOH A O 1 HETATM 7851 O O . HOH L 9 . ? 113.826 541.861 61.123 1.00 19.52 ? 1156 HOH A O 1 HETATM 7852 O O . HOH L 9 . ? 141.191 524.375 73.754 1.00 48.29 ? 1157 HOH A O 1 HETATM 7853 O O . HOH L 9 . ? 106.185 536.108 90.138 1.00 30.44 ? 1158 HOH A O 1 HETATM 7854 O O . HOH L 9 . ? 139.061 561.549 65.707 1.00 26.17 ? 1159 HOH A O 1 HETATM 7855 O O . HOH L 9 . ? 129.661 545.860 68.166 1.00 25.17 ? 1160 HOH A O 1 HETATM 7856 O O . HOH L 9 . ? 124.981 550.869 85.390 1.00 22.57 ? 1161 HOH A O 1 HETATM 7857 O O . HOH L 9 . ? 131.657 527.204 74.093 1.00 26.49 ? 1162 HOH A O 1 HETATM 7858 O O . HOH L 9 . ? 104.106 547.880 71.181 1.00 20.56 ? 1163 HOH A O 1 HETATM 7859 O O . HOH L 9 . ? 124.850 532.516 62.909 1.00 12.52 ? 1164 HOH A O 1 HETATM 7860 O O . HOH L 9 . ? 114.635 552.227 66.140 1.00 10.49 ? 1165 HOH A O 1 HETATM 7861 O O . HOH L 9 . ? 103.828 547.357 82.387 1.00 26.57 ? 1166 HOH A O 1 HETATM 7862 O O . HOH L 9 . ? 136.715 544.542 57.216 1.00 24.36 ? 1167 HOH A O 1 HETATM 7863 O O . HOH L 9 . ? 116.520 576.813 78.317 1.00 26.69 ? 1168 HOH A O 1 HETATM 7864 O O . HOH L 9 . ? 139.450 521.186 60.548 1.00 29.71 ? 1169 HOH A O 1 HETATM 7865 O O . HOH L 9 . ? 152.313 535.262 67.390 1.00 44.48 ? 1170 HOH A O 1 HETATM 7866 O O . HOH L 9 . ? 159.962 529.682 51.965 1.00 33.99 ? 1171 HOH A O 1 HETATM 7867 O O . HOH L 9 . ? 124.830 536.836 86.454 1.00 34.98 ? 1172 HOH A O 1 HETATM 7868 O O . HOH L 9 . ? 105.267 554.565 69.599 1.00 30.76 ? 1173 HOH A O 1 HETATM 7869 O O . HOH L 9 . ? 106.663 521.297 76.739 1.00 16.86 ? 1174 HOH A O 1 HETATM 7870 O O . HOH L 9 . ? 107.437 556.234 90.355 1.00 32.32 ? 1175 HOH A O 1 HETATM 7871 O O . HOH L 9 . ? 116.506 561.547 60.836 1.00 24.70 ? 1176 HOH A O 1 HETATM 7872 O O . HOH L 9 . ? 134.146 566.684 85.591 1.00 24.79 ? 1177 HOH A O 1 HETATM 7873 O O . HOH L 9 . ? 108.029 526.825 83.561 1.00 19.38 ? 1178 HOH A O 1 HETATM 7874 O O . HOH L 9 . ? 95.152 546.910 64.838 1.00 24.37 ? 1179 HOH A O 1 HETATM 7875 O O . HOH L 9 . ? 129.789 519.295 69.240 1.00 35.94 ? 1180 HOH A O 1 HETATM 7876 O O . HOH L 9 . ? 95.855 551.700 71.670 1.00 32.63 ? 1181 HOH A O 1 HETATM 7877 O O . HOH L 9 . ? 115.176 545.824 91.581 1.00 30.45 ? 1182 HOH A O 1 HETATM 7878 O O . HOH L 9 . ? 117.950 512.438 54.558 1.00 28.16 ? 1183 HOH A O 1 HETATM 7879 O O . HOH L 9 . ? 116.756 554.754 56.028 1.00 19.54 ? 1184 HOH A O 1 HETATM 7880 O O . HOH L 9 . ? 140.180 559.197 68.097 1.00 35.02 ? 1185 HOH A O 1 HETATM 7881 O O . HOH L 9 . ? 119.404 545.053 90.368 1.00 19.99 ? 1186 HOH A O 1 HETATM 7882 O O . HOH L 9 . ? 113.783 539.488 94.673 1.00 25.21 ? 1187 HOH A O 1 HETATM 7883 O O . HOH L 9 . ? 118.471 534.630 62.054 1.00 13.27 ? 1188 HOH A O 1 HETATM 7884 O O . HOH L 9 . ? 122.665 531.536 46.651 1.00 27.16 ? 1189 HOH A O 1 HETATM 7885 O O . HOH L 9 . ? 118.692 537.832 49.016 1.00 19.62 ? 1190 HOH A O 1 HETATM 7886 O O . HOH L 9 . ? 106.081 547.040 64.815 1.00 22.54 ? 1191 HOH A O 1 HETATM 7887 O O . HOH L 9 . ? 116.272 546.457 52.925 1.00 15.26 ? 1192 HOH A O 1 HETATM 7888 O O . HOH L 9 . ? 101.024 540.509 71.733 1.00 27.69 ? 1193 HOH A O 1 HETATM 7889 O O . HOH L 9 . ? 151.610 542.622 57.298 1.00 28.93 ? 1194 HOH A O 1 HETATM 7890 O O . HOH L 9 . ? 108.228 552.152 83.125 1.00 25.45 ? 1195 HOH A O 1 HETATM 7891 O O . HOH L 9 . ? 122.620 565.078 58.772 1.00 35.45 ? 1196 HOH A O 1 HETATM 7892 O O . HOH L 9 . ? 116.550 534.053 64.128 1.00 19.00 ? 1197 HOH A O 1 HETATM 7893 O O . HOH L 9 . ? 140.623 524.835 48.826 1.00 27.40 ? 1198 HOH A O 1 HETATM 7894 O O . HOH L 9 . ? 103.771 531.325 92.740 1.00 41.77 ? 1199 HOH A O 1 HETATM 7895 O O . HOH L 9 . ? 132.977 526.706 68.153 1.00 36.34 ? 1200 HOH A O 1 HETATM 7896 O O . HOH L 9 . ? 132.404 532.816 50.789 1.00 37.68 ? 1201 HOH A O 1 HETATM 7897 O O . HOH L 9 . ? 115.154 549.662 62.402 1.00 19.77 ? 1202 HOH A O 1 HETATM 7898 O O . HOH L 9 . ? 140.213 530.797 73.040 1.00 26.93 ? 1203 HOH A O 1 HETATM 7899 O O . HOH L 9 . ? 103.327 542.700 58.421 1.00 29.08 ? 1204 HOH A O 1 HETATM 7900 O O . HOH L 9 . ? 130.480 522.743 65.021 1.00 34.76 ? 1205 HOH A O 1 HETATM 7901 O O . HOH L 9 . ? 105.288 539.976 62.102 1.00 28.15 ? 1206 HOH A O 1 HETATM 7902 O O . HOH L 9 . ? 143.567 527.333 73.491 1.00 37.70 ? 1207 HOH A O 1 HETATM 7903 O O . HOH L 9 . ? 120.569 557.719 51.290 1.00 31.90 ? 1208 HOH A O 1 HETATM 7904 O O . HOH L 9 . ? 129.765 542.790 37.922 1.00 38.29 ? 1209 HOH A O 1 HETATM 7905 O O . HOH L 9 . ? 138.346 569.318 76.079 1.00 32.40 ? 1210 HOH A O 1 HETATM 7906 O O . HOH L 9 . ? 102.502 554.253 83.275 1.00 36.73 ? 1211 HOH A O 1 HETATM 7907 O O . HOH L 9 . ? 135.362 558.461 80.155 1.00 25.90 ? 1212 HOH A O 1 HETATM 7908 O O . HOH L 9 . ? 133.357 525.724 65.730 1.00 12.36 ? 1213 HOH A O 1 HETATM 7909 O O . HOH L 9 . ? 115.665 543.580 45.112 1.00 10.94 ? 1214 HOH A O 1 HETATM 7910 O O . HOH L 9 . ? 135.197 569.155 87.150 1.00 23.80 ? 1215 HOH A O 1 HETATM 7911 O O . HOH L 9 . ? 117.077 537.535 57.920 1.00 21.12 ? 1216 HOH A O 1 HETATM 7912 O O . HOH L 9 . ? 111.731 566.627 69.479 1.00 27.85 ? 1217 HOH A O 1 HETATM 7913 O O . HOH L 9 . ? 113.953 524.148 79.180 1.00 22.09 ? 1218 HOH A O 1 HETATM 7914 O O . HOH L 9 . ? 112.989 543.707 79.731 1.00 16.54 ? 1219 HOH A O 1 HETATM 7915 O O . HOH L 9 . ? 126.860 558.954 64.602 1.00 28.75 ? 1220 HOH A O 1 HETATM 7916 O O . HOH L 9 . ? 117.431 546.913 90.489 1.00 36.20 ? 1221 HOH A O 1 HETATM 7917 O O . HOH L 9 . ? 116.759 512.465 56.984 1.00 36.01 ? 1222 HOH A O 1 HETATM 7918 O O . HOH L 9 . ? 112.977 537.754 63.240 1.00 13.91 ? 1223 HOH A O 1 HETATM 7919 O O . HOH L 9 . ? 126.338 518.694 55.539 1.00 37.98 ? 1224 HOH A O 1 HETATM 7920 O O . HOH L 9 . ? 142.393 529.326 72.104 1.00 17.10 ? 1225 HOH A O 1 HETATM 7921 O O . HOH L 9 . ? 132.444 560.396 88.884 1.00 40.65 ? 1226 HOH A O 1 HETATM 7922 O O . HOH L 9 . ? 103.011 526.432 94.876 1.00 23.95 ? 1227 HOH A O 1 HETATM 7923 O O . HOH L 9 . ? 104.631 542.375 76.288 1.00 23.11 ? 1228 HOH A O 1 HETATM 7924 O O . HOH L 9 . ? 130.891 562.739 60.037 1.00 34.92 ? 1229 HOH A O 1 HETATM 7925 O O . HOH L 9 . ? 108.644 554.011 91.049 1.00 28.99 ? 1230 HOH A O 1 HETATM 7926 O O . HOH L 9 . ? 108.166 534.673 99.728 1.00 26.08 ? 1231 HOH A O 1 HETATM 7927 O O . HOH L 9 . ? 123.692 516.558 82.706 1.00 22.81 ? 1232 HOH A O 1 HETATM 7928 O O . HOH L 9 . ? 119.636 527.374 41.474 1.00 38.24 ? 1233 HOH A O 1 HETATM 7929 O O . HOH L 9 . ? 165.283 531.324 57.710 1.00 21.79 ? 1234 HOH A O 1 HETATM 7930 O O . HOH L 9 . ? 130.140 550.568 70.702 1.00 27.91 ? 1235 HOH A O 1 HETATM 7931 O O . HOH L 9 . ? 142.227 520.145 55.301 1.00 15.17 ? 1236 HOH A O 1 HETATM 7932 O O . HOH L 9 . ? 159.669 534.594 58.875 1.00 36.35 ? 1237 HOH A O 1 HETATM 7933 O O . HOH L 9 . ? 132.846 524.164 69.284 1.00 38.74 ? 1238 HOH A O 1 HETATM 7934 O O . HOH L 9 . ? 127.960 536.068 45.972 1.00 28.60 ? 1239 HOH A O 1 HETATM 7935 O O . HOH L 9 . ? 105.578 559.093 86.264 1.00 31.71 ? 1240 HOH A O 1 HETATM 7936 O O . HOH L 9 . ? 128.942 536.759 78.334 1.00 28.55 ? 1241 HOH A O 1 HETATM 7937 O O . HOH L 9 . ? 98.947 542.148 68.384 1.00 40.31 ? 1242 HOH A O 1 HETATM 7938 O O . HOH L 9 . ? 104.818 520.442 56.230 1.00 29.28 ? 1243 HOH A O 1 HETATM 7939 O O . HOH L 9 . ? 115.894 548.010 46.991 1.00 20.75 ? 1244 HOH A O 1 HETATM 7940 O O . HOH L 9 . ? 108.248 541.132 45.764 1.00 31.36 ? 1245 HOH A O 1 HETATM 7941 O O . HOH L 9 . ? 132.602 541.588 75.735 1.00 21.43 ? 1246 HOH A O 1 HETATM 7942 O O . HOH L 9 . ? 122.670 543.658 90.870 1.00 29.08 ? 1247 HOH A O 1 HETATM 7943 O O . HOH L 9 . ? 126.414 543.702 63.323 1.00 27.91 ? 1248 HOH A O 1 HETATM 7944 O O . HOH L 9 . ? 162.681 531.618 53.164 1.00 36.69 ? 1249 HOH A O 1 HETATM 7945 O O . HOH L 9 . ? 124.835 537.609 90.958 1.00 32.01 ? 1250 HOH A O 1 HETATM 7946 O O . HOH L 9 . ? 113.545 578.063 75.471 1.00 16.41 ? 1251 HOH A O 1 HETATM 7947 O O . HOH L 9 . ? 128.968 555.940 87.395 1.00 28.69 ? 1252 HOH A O 1 HETATM 7948 O O . HOH L 9 . ? 98.230 528.256 67.010 1.00 25.65 ? 1253 HOH A O 1 HETATM 7949 O O . HOH L 9 . ? 108.793 543.271 47.195 1.00 31.63 ? 1254 HOH A O 1 HETATM 7950 O O . HOH L 9 . ? 166.736 530.059 50.307 1.00 36.14 ? 1255 HOH A O 1 HETATM 7951 O O . HOH L 9 . ? 108.369 574.984 77.808 1.00 39.12 ? 1256 HOH A O 1 HETATM 7952 O O . HOH L 9 . ? 102.586 554.396 69.583 1.00 23.13 ? 1257 HOH A O 1 HETATM 7953 O O . HOH L 9 . ? 114.044 547.593 48.864 1.00 44.16 ? 1258 HOH A O 1 HETATM 7954 O O . HOH L 9 . ? 142.890 522.651 47.563 1.00 21.75 ? 1259 HOH A O 1 HETATM 7955 O O . HOH L 9 . ? 123.731 544.120 64.263 1.00 21.32 ? 1260 HOH A O 1 HETATM 7956 O O . HOH L 9 . ? 99.931 565.247 75.311 1.00 38.93 ? 1261 HOH A O 1 HETATM 7957 O O . HOH L 9 . ? 123.729 551.007 54.409 1.00 21.69 ? 1262 HOH A O 1 HETATM 7958 O O . HOH L 9 . ? 138.803 564.688 86.587 1.00 53.22 ? 1263 HOH A O 1 HETATM 7959 O O . HOH L 9 . ? 123.766 557.635 88.733 1.00 28.36 ? 1264 HOH A O 1 HETATM 7960 O O . HOH L 9 . ? 139.164 539.836 58.065 1.00 35.06 ? 1265 HOH A O 1 HETATM 7961 O O . HOH L 9 . ? 114.983 552.338 63.354 1.00 22.96 ? 1266 HOH A O 1 HETATM 7962 O O . HOH L 9 . ? 129.979 545.943 70.773 1.00 44.09 ? 1267 HOH A O 1 HETATM 7963 O O . HOH L 9 . ? 110.233 546.792 54.313 1.00 29.42 ? 1268 HOH A O 1 HETATM 7964 O O . HOH L 9 . ? 135.391 551.610 87.531 1.00 31.01 ? 1269 HOH A O 1 HETATM 7965 O O . HOH L 9 . ? 112.647 528.611 57.869 1.00 21.74 ? 1270 HOH A O 1 HETATM 7966 O O . HOH L 9 . ? 128.225 518.518 53.797 1.00 32.78 ? 1271 HOH A O 1 HETATM 7967 O O . HOH L 9 . ? 112.314 540.428 59.372 1.00 24.69 ? 1272 HOH A O 1 HETATM 7968 O O . HOH L 9 . ? 133.943 537.070 74.830 1.00 29.56 ? 1273 HOH A O 1 HETATM 7969 O O . HOH L 9 . ? 134.104 553.720 81.577 1.00 38.34 ? 1274 HOH A O 1 HETATM 7970 O O . HOH L 9 . ? 150.778 536.537 65.578 1.00 31.92 ? 1275 HOH A O 1 HETATM 7971 O O . HOH L 9 . ? 142.586 539.110 56.163 1.00 33.80 ? 1276 HOH A O 1 HETATM 7972 O O . HOH L 9 . ? 131.612 535.044 49.626 1.00 31.70 ? 1277 HOH A O 1 HETATM 7973 O O . HOH L 9 . ? 137.359 564.689 77.092 1.00 37.66 ? 1278 HOH A O 1 HETATM 7974 O O . HOH L 9 . ? 117.881 552.219 50.723 1.00 17.72 ? 1279 HOH A O 1 HETATM 7975 O O . HOH L 9 . ? 104.055 554.507 91.745 1.00 28.04 ? 1280 HOH A O 1 HETATM 7976 O O . HOH L 9 . ? 117.816 571.396 73.467 1.00 27.00 ? 1281 HOH A O 1 HETATM 7977 O O . HOH L 9 . ? 126.862 563.341 86.128 1.00 23.84 ? 1282 HOH A O 1 HETATM 7978 O O . HOH L 9 . ? 112.551 526.348 59.680 1.00 25.06 ? 1283 HOH A O 1 HETATM 7979 O O . HOH L 9 . ? 100.726 522.415 92.382 1.00 37.90 ? 1284 HOH A O 1 HETATM 7980 O O . HOH L 9 . ? 136.666 557.642 71.172 1.00 22.95 ? 1285 HOH A O 1 HETATM 7981 O O . HOH L 9 . ? 123.701 554.279 87.395 1.00 30.03 ? 1286 HOH A O 1 HETATM 7982 O O . HOH L 9 . ? 157.515 533.599 62.017 1.00 36.11 ? 1287 HOH A O 1 HETATM 7983 O O . HOH L 9 . ? 114.027 577.854 77.994 1.00 26.00 ? 1288 HOH A O 1 HETATM 7984 O O . HOH L 9 . ? 113.590 553.995 86.604 1.00 15.14 ? 1289 HOH A O 1 HETATM 7985 O O . HOH L 9 . ? 129.931 524.622 76.481 1.00 44.80 ? 1290 HOH A O 1 HETATM 7986 O O . HOH L 9 . ? 114.854 543.320 35.881 1.00 31.80 ? 1291 HOH A O 1 HETATM 7987 O O . HOH L 9 . ? 107.789 549.043 65.385 1.00 17.14 ? 1292 HOH A O 1 HETATM 7988 O O . HOH L 9 . ? 130.068 548.223 72.033 1.00 24.50 ? 1293 HOH A O 1 HETATM 7989 O O . HOH L 9 . ? 113.218 516.089 82.623 1.00 38.42 ? 1294 HOH A O 1 HETATM 7990 O O . HOH L 9 . ? 114.990 549.196 65.419 1.00 27.72 ? 1295 HOH A O 1 HETATM 7991 O O . HOH L 9 . ? 108.597 535.462 40.694 1.00 27.18 ? 1296 HOH A O 1 HETATM 7992 O O . HOH L 9 . ? 128.654 539.031 43.264 1.00 26.28 ? 1297 HOH A O 1 HETATM 7993 O O . HOH L 9 . ? 104.080 556.798 86.884 1.00 31.94 ? 1298 HOH A O 1 HETATM 7994 O O . HOH L 9 . ? 155.434 539.872 63.043 1.00 35.86 ? 1299 HOH A O 1 HETATM 7995 O O . HOH L 9 . ? 135.511 550.380 79.585 1.00 45.77 ? 1300 HOH A O 1 HETATM 7996 O O . HOH L 9 . ? 126.254 555.837 38.244 1.00 36.62 ? 1301 HOH A O 1 HETATM 7997 O O . HOH L 9 . ? 128.598 521.854 85.700 1.00 22.85 ? 1302 HOH A O 1 HETATM 7998 O O . HOH L 9 . ? 105.694 542.288 51.066 1.00 38.45 ? 1303 HOH A O 1 HETATM 7999 O O . HOH L 9 . ? 115.910 554.316 85.215 1.00 23.72 ? 1304 HOH A O 1 HETATM 8000 O O . HOH L 9 . ? 119.915 519.574 45.369 1.00 36.95 ? 1305 HOH A O 1 HETATM 8001 O O . HOH L 9 . ? 155.397 527.172 57.710 1.00 32.43 ? 1306 HOH A O 1 HETATM 8002 O O . HOH L 9 . ? 119.800 511.318 78.860 1.00 43.23 ? 1307 HOH A O 1 HETATM 8003 O O . HOH L 9 . ? 157.368 531.222 40.276 1.00 25.50 ? 1308 HOH A O 1 HETATM 8004 O O . HOH L 9 . ? 134.291 550.945 36.385 1.00 29.19 ? 1309 HOH A O 1 HETATM 8005 O O . HOH L 9 . ? 113.918 523.009 40.392 1.00 39.45 ? 1310 HOH A O 1 HETATM 8006 O O . HOH L 9 . ? 96.681 545.129 77.074 1.00 32.11 ? 1311 HOH A O 1 HETATM 8007 O O . HOH L 9 . ? 152.995 532.982 66.208 1.00 23.35 ? 1312 HOH A O 1 HETATM 8008 O O . HOH L 9 . ? 141.933 517.489 55.907 1.00 38.98 ? 1313 HOH A O 1 HETATM 8009 O O . HOH L 9 . ? 105.215 539.466 50.630 1.00 38.65 ? 1314 HOH A O 1 HETATM 8010 O O . HOH L 9 . ? 103.380 546.907 64.874 1.00 24.08 ? 1315 HOH A O 1 HETATM 8011 O O . HOH L 9 . ? 110.738 548.660 72.956 1.00 30.23 ? 1316 HOH A O 1 HETATM 8012 O O . HOH L 9 . ? 103.274 545.655 57.897 1.00 22.56 ? 1317 HOH A O 1 HETATM 8013 O O . HOH L 9 . ? 101.661 556.906 83.462 1.00 34.69 ? 1318 HOH A O 1 HETATM 8014 O O . HOH L 9 . ? 152.124 530.972 67.817 1.00 30.69 ? 1319 HOH A O 1 HETATM 8015 O O . HOH L 9 . ? 128.412 536.460 71.614 1.00 21.21 ? 1320 HOH A O 1 HETATM 8016 O O . HOH L 9 . ? 105.075 518.127 77.237 1.00 35.97 ? 1321 HOH A O 1 HETATM 8017 O O . HOH L 9 . ? 139.382 525.392 53.923 1.00 30.53 ? 1322 HOH A O 1 HETATM 8018 O O . HOH L 9 . ? 130.679 522.529 72.439 1.00 25.62 ? 1323 HOH A O 1 HETATM 8019 O O . HOH L 9 . ? 130.448 559.863 85.665 1.00 34.84 ? 1324 HOH A O 1 HETATM 8020 O O . HOH L 9 . ? 151.895 549.900 46.057 1.00 29.97 ? 1325 HOH A O 1 HETATM 8021 O O . HOH L 9 . ? 131.286 539.995 77.521 1.00 28.79 ? 1326 HOH A O 1 HETATM 8022 O O . HOH L 9 . ? 126.057 510.626 56.628 1.00 29.06 ? 1327 HOH A O 1 HETATM 8023 O O . HOH L 9 . ? 150.806 533.139 74.219 1.00 36.24 ? 1328 HOH A O 1 HETATM 8024 O O . HOH L 9 . ? 117.308 547.317 43.065 1.00 28.90 ? 1329 HOH A O 1 HETATM 8025 O O . HOH L 9 . ? 117.371 556.508 86.094 1.00 34.12 ? 1330 HOH A O 1 HETATM 8026 O O . HOH L 9 . ? 129.387 541.616 81.922 1.00 32.59 ? 1331 HOH A O 1 HETATM 8027 O O . HOH L 9 . ? 141.211 566.346 83.261 1.00 37.46 ? 1332 HOH A O 1 HETATM 8028 O O . HOH L 9 . ? 120.133 556.026 85.747 1.00 29.49 ? 1333 HOH A O 1 HETATM 8029 O O . HOH L 9 . ? 104.015 550.501 71.630 1.00 30.08 ? 1334 HOH A O 1 HETATM 8030 O O . HOH L 9 . ? 118.061 559.170 81.819 1.00 18.26 ? 1335 HOH A O 1 HETATM 8031 O O . HOH L 9 . ? 102.035 530.863 61.143 1.00 37.56 ? 1336 HOH A O 1 HETATM 8032 O O . HOH L 9 . ? 133.788 544.835 63.766 1.00 13.69 ? 1337 HOH A O 1 HETATM 8033 O O . HOH L 9 . ? 109.979 524.007 45.980 1.00 30.02 ? 1338 HOH A O 1 HETATM 8034 O O . HOH L 9 . ? 133.244 559.575 52.814 1.00 22.52 ? 1339 HOH A O 1 HETATM 8035 O O . HOH L 9 . ? 101.941 541.688 60.624 1.00 33.00 ? 1340 HOH A O 1 HETATM 8036 O O . HOH L 9 . ? 111.043 518.856 88.807 1.00 29.40 ? 1341 HOH A O 1 HETATM 8037 O O . HOH L 9 . ? 115.244 559.248 54.364 1.00 35.60 ? 1342 HOH A O 1 HETATM 8038 O O . HOH L 9 . ? 108.332 530.893 44.565 1.00 32.08 ? 1343 HOH A O 1 HETATM 8039 O O . HOH L 9 . ? 113.172 534.756 39.991 1.00 22.72 ? 1344 HOH A O 1 HETATM 8040 O O . HOH L 9 . ? 128.294 550.830 68.806 1.00 34.43 ? 1345 HOH A O 1 HETATM 8041 O O . HOH L 9 . ? 127.440 515.179 74.154 1.00 32.89 ? 1346 HOH A O 1 HETATM 8042 O O . HOH L 9 . ? 124.480 523.721 44.934 1.00 28.83 ? 1347 HOH A O 1 HETATM 8043 O O . HOH L 9 . ? 99.492 551.011 69.620 1.00 26.76 ? 1348 HOH A O 1 HETATM 8044 O O . HOH L 9 . ? 125.874 518.616 46.340 1.00 46.06 ? 1349 HOH A O 1 HETATM 8045 O O . HOH L 9 . ? 100.788 531.216 54.467 1.00 26.92 ? 1350 HOH A O 1 HETATM 8046 O O . HOH L 9 . ? 140.588 543.604 58.831 1.00 38.65 ? 1351 HOH A O 1 HETATM 8047 O O . HOH L 9 . ? 105.701 534.557 50.107 1.00 33.32 ? 1352 HOH A O 1 HETATM 8048 O O . HOH L 9 . ? 99.211 541.839 60.866 1.00 29.25 ? 1353 HOH A O 1 HETATM 8049 O O . HOH L 9 . ? 130.360 523.524 79.066 1.00 32.35 ? 1354 HOH A O 1 HETATM 8050 O O . HOH L 9 . ? 142.199 551.538 50.959 1.00 39.64 ? 1355 HOH A O 1 HETATM 8051 O O . HOH L 9 . ? 136.328 537.182 45.270 1.00 33.75 ? 1356 HOH A O 1 HETATM 8052 O O . HOH L 9 . ? 134.346 559.495 49.123 1.00 17.93 ? 1357 HOH A O 1 HETATM 8053 O O . HOH L 9 . ? 127.867 525.757 87.732 1.00 39.03 ? 1358 HOH A O 1 HETATM 8054 O O . HOH L 9 . ? 105.365 549.367 96.130 1.00 29.62 ? 1359 HOH A O 1 HETATM 8055 O O . HOH L 9 . ? 113.682 515.857 58.303 1.00 35.82 ? 1360 HOH A O 1 HETATM 8056 O O . HOH L 9 . ? 109.612 516.816 56.891 1.00 41.95 ? 1361 HOH A O 1 HETATM 8057 O O . HOH L 9 . ? 114.835 556.482 55.419 1.00 34.14 ? 1362 HOH A O 1 HETATM 8058 O O . HOH L 9 . ? 129.203 523.232 87.913 1.00 34.85 ? 1363 HOH A O 1 HETATM 8059 O O . HOH L 9 . ? 121.615 545.586 92.339 1.00 31.70 ? 1364 HOH A O 1 HETATM 8060 O O . HOH L 9 . ? 114.656 548.260 51.344 1.00 34.16 ? 1365 HOH A O 1 HETATM 8061 O O . HOH L 9 . ? 132.418 521.794 79.584 1.00 34.96 ? 1366 HOH A O 1 HETATM 8062 O O . HOH L 9 . ? 133.067 537.886 77.275 1.00 32.13 ? 1367 HOH A O 1 HETATM 8063 O O . HOH M 9 . ? 145.783 526.588 41.665 1.00 38.80 ? 301 HOH B O 1 HETATM 8064 O O . HOH M 9 . ? 151.839 511.479 45.700 1.00 35.60 ? 302 HOH B O 1 HETATM 8065 O O . HOH M 9 . ? 138.846 512.468 48.757 1.00 24.47 ? 303 HOH B O 1 HETATM 8066 O O . HOH M 9 . ? 136.800 519.033 50.056 1.00 26.93 ? 304 HOH B O 1 HETATM 8067 O O . HOH M 9 . ? 130.748 519.399 51.376 1.00 28.75 ? 305 HOH B O 1 HETATM 8068 O O . HOH M 9 . ? 130.528 490.338 59.666 1.00 45.59 ? 306 HOH B O 1 HETATM 8069 O O . HOH M 9 . ? 142.512 524.461 43.650 1.00 21.39 ? 307 HOH B O 1 HETATM 8070 O O . HOH M 9 . ? 131.937 517.251 56.814 1.00 23.09 ? 308 HOH B O 1 HETATM 8071 O O . HOH M 9 . ? 128.288 510.888 58.191 1.00 25.40 ? 309 HOH B O 1 HETATM 8072 O O . HOH M 9 . ? 143.149 516.791 53.409 1.00 22.57 ? 310 HOH B O 1 HETATM 8073 O O . HOH M 9 . ? 145.070 520.407 55.460 1.00 38.07 ? 311 HOH B O 1 HETATM 8074 O O . HOH M 9 . ? 139.525 507.472 47.338 1.00 23.13 ? 312 HOH B O 1 HETATM 8075 O O . HOH M 9 . ? 139.712 515.841 47.341 1.00 16.07 ? 313 HOH B O 1 HETATM 8076 O O . HOH M 9 . ? 138.684 522.911 48.205 1.00 37.70 ? 314 HOH B O 1 HETATM 8077 O O . HOH M 9 . ? 142.479 510.392 62.897 1.00 38.16 ? 315 HOH B O 1 HETATM 8078 O O . HOH M 9 . ? 131.355 510.215 63.915 1.00 35.36 ? 316 HOH B O 1 HETATM 8079 O O . HOH M 9 . ? 130.808 517.514 54.211 1.00 16.55 ? 317 HOH B O 1 HETATM 8080 O O . HOH M 9 . ? 129.100 510.735 54.337 1.00 23.23 ? 318 HOH B O 1 HETATM 8081 O O . HOH M 9 . ? 133.823 504.181 61.421 1.00 42.95 ? 319 HOH B O 1 HETATM 8082 O O . HOH M 9 . ? 129.486 511.623 51.506 1.00 21.30 ? 320 HOH B O 1 HETATM 8083 O O . HOH M 9 . ? 141.911 517.399 59.323 1.00 41.08 ? 321 HOH B O 1 HETATM 8084 O O . HOH M 9 . ? 144.193 507.783 47.693 1.00 19.52 ? 322 HOH B O 1 HETATM 8085 O O . HOH M 9 . ? 136.630 521.632 49.341 1.00 24.22 ? 323 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 VAL 1 33 33 VAL VAL A . n A 1 2 ASP 2 34 34 ASP ASP A . n A 1 3 ARG 3 35 35 ARG ARG A . n A 1 4 SER 4 36 36 SER SER A . n A 1 5 ASN 5 37 37 ASN ASN A . n A 1 6 PHE 6 38 38 PHE PHE A . n A 1 7 LYS 7 39 39 LYS LYS A . n A 1 8 THR 8 40 40 THR THR A . n A 1 9 CYS 9 41 41 CYS CYS A . n A 1 10 ASP 10 42 42 ASP ASP A . n A 1 11 GLU 11 43 43 GLU GLU A . n A 1 12 SER 12 44 44 SER SER A . n A 1 13 SER 13 45 45 SER SER A . n A 1 14 PHE 14 46 46 PHE PHE A . n A 1 15 CYS 15 47 47 CYS CYS A . n A 1 16 LYS 16 48 48 LYS LYS A . n A 1 17 ARG 17 49 49 ARG ARG A . n A 1 18 GLN 18 50 50 GLN GLN A . n A 1 19 ARG 19 51 51 ARG ARG A . n A 1 20 SER 20 52 52 SER SER A . n A 1 21 ILE 21 53 53 ILE ILE A . n A 1 22 ARG 22 54 54 ARG ARG A . n A 1 23 PRO 23 55 55 PRO PRO A . n A 1 24 GLY 24 56 56 GLY GLY A . n A 1 25 LEU 25 57 57 LEU LEU A . n A 1 26 SER 26 58 58 SER SER A . n A 1 27 PRO 27 59 59 PRO PRO A . n A 1 28 TYR 28 60 60 TYR TYR A . n A 1 29 ARG 29 61 61 ARG ARG A . n A 1 30 ALA 30 62 62 ALA ALA A . n A 1 31 LEU 31 63 63 LEU LEU A . n A 1 32 LEU 32 64 64 LEU LEU A . n A 1 33 ASP 33 65 65 ASP ASP A . n A 1 34 THR 34 66 66 THR THR A . n A 1 35 LEU 35 67 67 LEU LEU A . n A 1 36 GLN 36 68 68 GLN GLN A . n A 1 37 LEU 37 69 69 LEU LEU A . n A 1 38 GLY 38 70 70 GLY GLY A . n A 1 39 PRO 39 71 71 PRO PRO A . n A 1 40 ASP 40 72 72 ASP ASP A . n A 1 41 ALA 41 73 73 ALA ALA A . n A 1 42 LEU 42 74 74 LEU LEU A . n A 1 43 THR 43 75 75 THR THR A . n A 1 44 VAL 44 76 76 VAL VAL A . n A 1 45 HIS 45 77 77 HIS HIS A . n A 1 46 LEU 46 78 78 LEU LEU A . n A 1 47 ILE 47 79 79 ILE ILE A . n A 1 48 HIS 48 80 80 HIS HIS A . n A 1 49 GLU 49 81 81 GLU GLU A . n A 1 50 VAL 50 82 82 VAL VAL A . n A 1 51 THR 51 83 83 THR THR A . n A 1 52 LYS 52 84 84 LYS LYS A . n A 1 53 VAL 53 85 85 VAL VAL A . n A 1 54 LEU 54 86 86 LEU LEU A . n A 1 55 LEU 55 87 87 LEU LEU A . n A 1 56 VAL 56 88 88 VAL VAL A . n A 1 57 LEU 57 89 89 LEU LEU A . n A 1 58 GLU 58 90 90 GLU GLU A . n A 1 59 LEU 59 91 91 LEU LEU A . n A 1 60 GLN 60 92 92 GLN GLN A . n A 1 61 GLY 61 93 93 GLY GLY A . n A 1 62 LEU 62 94 94 LEU LEU A . n A 1 63 GLN 63 95 95 GLN GLN A . n A 1 64 LYS 64 96 96 LYS LYS A . n A 1 65 ASN 65 97 97 ASN ASN A . n A 1 66 MET 66 98 98 MET MET A . n A 1 67 THR 67 99 99 THR THR A . n A 1 68 ARG 68 100 100 ARG ARG A . n A 1 69 ILE 69 101 101 ILE ILE A . n A 1 70 ARG 70 102 102 ARG ARG A . n A 1 71 ILE 71 103 103 ILE ILE A . n A 1 72 ASP 72 104 104 ASP ASP A . n A 1 73 GLU 73 105 105 GLU GLU A . n A 1 74 LEU 74 106 106 LEU LEU A . n A 1 75 GLU 75 107 107 GLU GLU A . n A 1 76 PRO 76 108 108 PRO PRO A . n A 1 77 ARG 77 109 109 ARG ARG A . n A 1 78 ARG 78 110 110 ARG ARG A . n A 1 79 PRO 79 111 111 PRO PRO A . n A 1 80 ARG 80 112 112 ARG ARG A . n A 1 81 TYR 81 113 113 TYR TYR A . n A 1 82 ARG 82 114 114 ARG ARG A . n A 1 83 VAL 83 115 115 VAL VAL A . n A 1 84 PRO 84 116 116 PRO PRO A . n A 1 85 ASP 85 117 117 ASP ASP A . n A 1 86 VAL 86 118 118 VAL VAL A . n A 1 87 LEU 87 119 119 LEU LEU A . n A 1 88 VAL 88 120 120 VAL VAL A . n A 1 89 ALA 89 121 121 ALA ALA A . n A 1 90 ASP 90 122 122 ASP ASP A . n A 1 91 PRO 91 123 123 PRO PRO A . n A 1 92 PRO 92 124 124 PRO PRO A . n A 1 93 THR 93 125 125 THR THR A . n A 1 94 ALA 94 126 126 ALA ALA A . n A 1 95 ARG 95 127 127 ARG ARG A . n A 1 96 LEU 96 128 128 LEU LEU A . n A 1 97 SER 97 129 129 SER SER A . n A 1 98 VAL 98 130 130 VAL VAL A . n A 1 99 SER 99 131 131 SER SER A . n A 1 100 GLY 100 132 132 GLY GLY A . n A 1 101 ARG 101 133 133 ARG ARG A . n A 1 102 ASP 102 134 134 ASP ASP A . n A 1 103 ASP 103 135 135 ASP ASP A . n A 1 104 ASN 104 136 136 ASN ASN A . n A 1 105 SER 105 137 137 SER SER A . n A 1 106 VAL 106 138 138 VAL VAL A . n A 1 107 GLU 107 139 139 GLU GLU A . n A 1 108 LEU 108 140 140 LEU LEU A . n A 1 109 THR 109 141 141 THR THR A . n A 1 110 VAL 110 142 142 VAL VAL A . n A 1 111 ALA 111 143 143 ALA ALA A . n A 1 112 GLU 112 144 144 GLU GLU A . n A 1 113 GLY 113 145 145 GLY GLY A . n A 1 114 PRO 114 146 146 PRO PRO A . n A 1 115 TYR 115 147 147 TYR TYR A . n A 1 116 LYS 116 148 148 LYS LYS A . n A 1 117 ILE 117 149 149 ILE ILE A . n A 1 118 ILE 118 150 150 ILE ILE A . n A 1 119 LEU 119 151 151 LEU LEU A . n A 1 120 THR 120 152 152 THR THR A . n A 1 121 ALA 121 153 153 ALA ALA A . n A 1 122 GLN 122 154 154 GLN GLN A . n A 1 123 PRO 123 155 155 PRO PRO A . n A 1 124 PHE 124 156 156 PHE PHE A . n A 1 125 ARG 125 157 157 ARG ARG A . n A 1 126 LEU 126 158 158 LEU LEU A . n A 1 127 ASP 127 159 159 ASP ASP A . n A 1 128 LEU 128 160 160 LEU LEU A . n A 1 129 LEU 129 161 161 LEU LEU A . n A 1 130 GLU 130 162 162 GLU GLU A . n A 1 131 ASP 131 163 163 ASP ASP A . n A 1 132 ARG 132 164 164 ARG ARG A . n A 1 133 SER 133 165 165 SER SER A . n A 1 134 LEU 134 166 166 LEU LEU A . n A 1 135 LEU 135 167 167 LEU LEU A . n A 1 136 LEU 136 168 168 LEU LEU A . n A 1 137 SER 137 169 169 SER SER A . n A 1 138 VAL 138 170 170 VAL VAL A . n A 1 139 ASN 139 171 171 ASN ASN A . n A 1 140 ALA 140 172 172 ALA ALA A . n A 1 141 ARG 141 173 173 ARG ARG A . n A 1 142 GLY 142 174 174 GLY GLY A . n A 1 143 LEU 143 175 175 LEU LEU A . n A 1 144 MET 144 176 176 MET MET A . n A 1 145 ALA 145 177 177 ALA ALA A . n A 1 146 PHE 146 178 178 PHE PHE A . n A 1 147 GLU 147 179 179 GLU GLU A . n A 1 148 HIS 148 180 180 HIS HIS A . n A 1 149 GLN 149 181 181 GLN GLN A . n A 1 150 ARG 150 182 182 ARG ARG A . n A 1 151 ALA 151 183 183 ALA ALA A . n A 1 152 PRO 152 184 184 PRO PRO A . n A 1 153 ARG 153 185 185 ARG ARG A . n A 1 154 VAL 154 208 ? ? ? A . n A 1 155 PRO 155 209 ? ? ? A . n A 1 156 GLN 156 210 ? ? ? A . n A 1 157 GLU 157 211 ? ? ? A . n A 1 158 SER 158 212 ? ? ? A . n A 1 159 LYS 159 213 ? ? ? A . n A 1 160 ASP 160 214 ? ? ? A . n A 1 161 PRO 161 215 ? ? ? A . n A 1 162 ALA 162 216 ? ? ? A . n A 1 163 GLU 163 217 ? ? ? A . n A 1 164 GLY 164 218 ? ? ? A . n A 1 165 ASN 165 219 ? ? ? A . n A 1 166 GLY 166 220 ? ? ? A . n A 1 167 ALA 167 221 ? ? ? A . n A 1 168 GLN 168 222 ? ? ? A . n A 1 169 PRO 169 223 ? ? ? A . n A 1 170 GLU 170 224 ? ? ? A . n A 1 171 ALA 171 225 ? ? ? A . n A 1 172 THR 172 226 ? ? ? A . n A 1 173 PRO 173 227 ? ? ? A . n A 1 174 GLY 174 228 ? ? ? A . n A 1 175 ASP 175 229 ? ? ? A . n A 1 176 GLY 176 230 ? ? ? A . n A 1 177 ASP 177 231 ? ? ? A . n A 1 178 LYS 178 232 ? ? ? A . n A 1 179 PRO 179 233 ? ? ? A . n A 1 180 GLU 180 234 ? ? ? A . n A 1 181 GLU 181 235 ? ? ? A . n A 1 182 THR 182 236 ? ? ? A . n A 1 183 GLN 183 237 ? ? ? A . n A 1 184 GLU 184 238 ? ? ? A . n A 1 185 LYS 185 239 ? ? ? A . n A 1 186 ALA 186 240 ? ? ? A . n A 1 187 GLU 187 241 ? ? ? A . n A 1 188 LYS 188 242 ? ? ? A . n A 1 189 ASP 189 243 ? ? ? A . n A 1 190 GLU 190 244 244 GLU GLU A . n A 1 191 PRO 191 245 245 PRO PRO A . n A 1 192 GLY 192 246 246 GLY GLY A . n A 1 193 ALA 193 247 247 ALA ALA A . n A 1 194 TRP 194 248 248 TRP TRP A . n A 1 195 GLU 195 249 249 GLU GLU A . n A 1 196 GLU 196 250 250 GLU GLU A . n A 1 197 THR 197 251 251 THR THR A . n A 1 198 PHE 198 252 252 PHE PHE A . n A 1 199 LYS 199 253 253 LYS LYS A . n A 1 200 THR 200 254 254 THR THR A . n A 1 201 HIS 201 255 255 HIS HIS A . n A 1 202 SER 202 256 256 SER SER A . n A 1 203 ASP 203 257 257 ASP ASP A . n A 1 204 SER 204 258 258 SER SER A . n A 1 205 LYS 205 259 259 LYS LYS A . n A 1 206 PRO 206 260 260 PRO PRO A . n A 1 207 TYR 207 261 261 TYR TYR A . n A 1 208 GLY 208 262 262 GLY GLY A . n A 1 209 PRO 209 263 263 PRO PRO A . n A 1 210 THR 210 264 264 THR THR A . n A 1 211 SER 211 265 265 SER SER A . n A 1 212 VAL 212 266 266 VAL VAL A . n A 1 213 GLY 213 267 267 GLY GLY A . n A 1 214 LEU 214 268 268 LEU LEU A . n A 1 215 ASP 215 269 269 ASP ASP A . n A 1 216 PHE 216 270 270 PHE PHE A . n A 1 217 SER 217 271 271 SER SER A . n A 1 218 LEU 218 272 272 LEU LEU A . n A 1 219 PRO 219 273 273 PRO PRO A . n A 1 220 GLY 220 274 274 GLY GLY A . n A 1 221 MET 221 275 275 MET MET A . n A 1 222 GLU 222 276 276 GLU GLU A . n A 1 223 HIS 223 277 277 HIS HIS A . n A 1 224 VAL 224 278 278 VAL VAL A . n A 1 225 TYR 225 279 279 TYR TYR A . n A 1 226 GLY 226 280 280 GLY GLY A . n A 1 227 ILE 227 281 281 ILE ILE A . n A 1 228 PRO 228 282 282 PRO PRO A . n A 1 229 GLU 229 283 283 GLU GLU A . n A 1 230 HIS 230 284 284 HIS HIS A . n A 1 231 ALA 231 285 285 ALA ALA A . n A 1 232 ASP 232 286 286 ASP ASP A . n A 1 233 SER 233 287 287 SER SER A . n A 1 234 LEU 234 288 288 LEU LEU A . n A 1 235 ARG 235 289 289 ARG ARG A . n A 1 236 LEU 236 290 290 LEU LEU A . n A 1 237 LYS 237 291 291 LYS LYS A . n A 1 238 VAL 238 292 292 VAL VAL A . n A 1 239 THR 239 293 293 THR THR A . n A 1 240 GLU 240 294 294 GLU GLU A . n A 1 241 GLY 241 295 295 GLY GLY A . n A 1 242 GLY 242 296 296 GLY GLY A . n A 1 243 GLU 243 297 297 GLU GLU A . n A 1 244 PRO 244 298 298 PRO PRO A . n A 1 245 TYR 245 299 299 TYR TYR A . n A 1 246 ARG 246 300 300 ARG ARG A . n A 1 247 LEU 247 301 301 LEU LEU A . n A 1 248 TYR 248 302 302 TYR TYR A . n A 1 249 ASN 249 303 303 ASN ASN A . n A 1 250 LEU 250 304 304 LEU LEU A . n A 1 251 ASP 251 305 305 ASP ASP A . n A 1 252 VAL 252 306 306 VAL VAL A . n A 1 253 PHE 253 307 307 PHE PHE A . n A 1 254 GLN 254 308 308 GLN GLN A . n A 1 255 TYR 255 309 309 TYR TYR A . n A 1 256 GLU 256 310 310 GLU GLU A . n A 1 257 LEU 257 311 311 LEU LEU A . n A 1 258 ASN 258 312 312 ASN ASN A . n A 1 259 ASN 259 313 313 ASN ASN A . n A 1 260 PRO 260 314 314 PRO PRO A . n A 1 261 MET 261 315 315 MET MET A . n A 1 262 ALA 262 316 316 ALA ALA A . n A 1 263 LEU 263 317 317 LEU LEU A . n A 1 264 TYR 264 318 318 TYR TYR A . n A 1 265 GLY 265 319 319 GLY GLY A . n A 1 266 SER 266 320 320 SER SER A . n A 1 267 VAL 267 321 321 VAL VAL A . n A 1 268 PRO 268 322 322 PRO PRO A . n A 1 269 VAL 269 323 323 VAL VAL A . n A 1 270 LEU 270 324 324 LEU LEU A . n A 1 271 LEU 271 325 325 LEU LEU A . n A 1 272 ALA 272 326 326 ALA ALA A . n A 1 273 HIS 273 327 327 HIS HIS A . n A 1 274 SER 274 328 328 SER SER A . n A 1 275 PHE 275 329 329 PHE PHE A . n A 1 276 HIS 276 330 330 HIS HIS A . n A 1 277 ARG 277 331 331 ARG ARG A . n A 1 278 ASP 278 332 332 ASP ASP A . n A 1 279 LEU 279 333 333 LEU LEU A . n A 1 280 GLY 280 334 334 GLY GLY A . n A 1 281 ILE 281 335 335 ILE ILE A . n A 1 282 PHE 282 336 336 PHE PHE A . n A 1 283 TRP 283 337 337 TRP TRP A . n A 1 284 LEU 284 338 338 LEU LEU A . n A 1 285 ASN 285 339 339 ASN ASN A . n A 1 286 ALA 286 340 340 ALA ALA A . n A 1 287 ALA 287 341 341 ALA ALA A . n A 1 288 GLU 288 342 342 GLU GLU A . n A 1 289 THR 289 343 343 THR THR A . n A 1 290 TRP 290 344 344 TRP TRP A . n A 1 291 VAL 291 345 345 VAL VAL A . n A 1 292 ASP 292 346 346 ASP ASP A . n A 1 293 ILE 293 347 347 ILE ILE A . n A 1 294 SER 294 348 348 SER SER A . n A 1 295 SER 295 349 349 SER SER A . n A 1 296 ASN 296 350 350 ASN ASN A . n A 1 297 THR 297 351 ? ? ? A . n A 1 298 ALA 298 352 ? ? ? A . n A 1 299 GLY 299 353 ? ? ? A . n A 1 300 LYS 300 354 ? ? ? A . n A 1 301 THR 301 355 ? ? ? A . n A 1 302 LEU 302 356 ? ? ? A . n A 1 303 PHE 303 357 ? ? ? A . n A 1 304 GLY 304 358 ? ? ? A . n A 1 305 LYS 305 359 ? ? ? A . n A 1 306 MET 306 360 ? ? ? A . n A 1 307 LEU 307 361 ? ? ? A . n A 1 308 ASP 308 362 ? ? ? A . n A 1 309 TYR 309 363 ? ? ? A . n A 1 310 LEU 310 364 ? ? ? A . n A 1 311 GLN 311 365 ? ? ? A . n A 1 312 GLY 312 366 ? ? ? A . n A 1 313 SER 313 367 ? ? ? A . n A 1 314 GLY 314 368 ? ? ? A . n A 1 315 GLU 315 369 ? ? ? A . n A 1 316 THR 316 370 370 THR THR A . n A 1 317 PRO 317 371 371 PRO PRO A . n A 1 318 GLN 318 372 372 GLN GLN A . n A 1 319 THR 319 373 373 THR THR A . n A 1 320 ASP 320 374 374 ASP ASP A . n A 1 321 ILE 321 375 375 ILE ILE A . n A 1 322 ARG 322 376 376 ARG ARG A . n A 1 323 TRP 323 377 377 TRP TRP A . n A 1 324 MET 324 378 378 MET MET A . n A 1 325 SER 325 379 379 SER SER A . n A 1 326 GLU 326 380 380 GLU GLU A . n A 1 327 SER 327 381 381 SER SER A . n A 1 328 GLY 328 382 382 GLY GLY A . n A 1 329 ILE 329 383 383 ILE ILE A . n A 1 330 ILE 330 384 384 ILE ILE A . n A 1 331 ASP 331 385 385 ASP ASP A . n A 1 332 VAL 332 386 386 VAL VAL A . n A 1 333 PHE 333 387 387 PHE PHE A . n A 1 334 LEU 334 388 388 LEU LEU A . n A 1 335 MET 335 389 389 MET MET A . n A 1 336 LEU 336 390 390 LEU LEU A . n A 1 337 GLY 337 391 391 GLY GLY A . n A 1 338 PRO 338 392 392 PRO PRO A . n A 1 339 SER 339 393 393 SER SER A . n A 1 340 VAL 340 394 394 VAL VAL A . n A 1 341 PHE 341 395 395 PHE PHE A . n A 1 342 ASP 342 396 396 ASP ASP A . n A 1 343 VAL 343 397 397 VAL VAL A . n A 1 344 PHE 344 398 398 PHE PHE A . n A 1 345 ARG 345 399 399 ARG ARG A . n A 1 346 GLN 346 400 400 GLN GLN A . n A 1 347 TYR 347 401 401 TYR TYR A . n A 1 348 ALA 348 402 402 ALA ALA A . n A 1 349 SER 349 403 403 SER SER A . n A 1 350 LEU 350 404 404 LEU LEU A . n A 1 351 THR 351 405 405 THR THR A . n A 1 352 GLY 352 406 406 GLY GLY A . n A 1 353 THR 353 407 407 THR THR A . n A 1 354 GLN 354 408 408 GLN GLN A . n A 1 355 ALA 355 409 409 ALA ALA A . n A 1 356 LEU 356 410 410 LEU LEU A . n A 1 357 PRO 357 411 411 PRO PRO A . n A 1 358 PRO 358 412 412 PRO PRO A . n A 1 359 LEU 359 413 413 LEU LEU A . n A 1 360 PHE 360 414 414 PHE PHE A . n A 1 361 SER 361 415 415 SER SER A . n A 1 362 LEU 362 416 416 LEU LEU A . n A 1 363 GLY 363 417 417 GLY GLY A . n A 1 364 TYR 364 418 418 TYR TYR A . n A 1 365 HIS 365 419 419 HIS HIS A . n A 1 366 GLN 366 420 420 GLN GLN A . n A 1 367 SER 367 421 421 SER SER A . n A 1 368 ARG 368 422 422 ARG ARG A . n A 1 369 TRP 369 423 423 TRP TRP A . n A 1 370 ASN 370 424 424 ASN ASN A . n A 1 371 TYR 371 425 425 TYR TYR A . n A 1 372 ARG 372 426 426 ARG ARG A . n A 1 373 ASP 373 427 427 ASP ASP A . n A 1 374 GLU 374 428 428 GLU GLU A . n A 1 375 ALA 375 429 429 ALA ALA A . n A 1 376 ASP 376 430 430 ASP ASP A . n A 1 377 VAL 377 431 431 VAL VAL A . n A 1 378 LEU 378 432 432 LEU LEU A . n A 1 379 GLU 379 433 433 GLU GLU A . n A 1 380 VAL 380 434 434 VAL VAL A . n A 1 381 ASP 381 435 435 ASP ASP A . n A 1 382 GLN 382 436 436 GLN GLN A . n A 1 383 GLY 383 437 437 GLY GLY A . n A 1 384 PHE 384 438 438 PHE PHE A . n A 1 385 ASP 385 439 439 ASP ASP A . n A 1 386 ASP 386 440 440 ASP ASP A . n A 1 387 HIS 387 441 441 HIS HIS A . n A 1 388 ASN 388 442 442 ASN ASN A . n A 1 389 MET 389 443 443 MET MET A . n A 1 390 PRO 390 444 444 PRO PRO A . n A 1 391 CYS 391 445 445 CYS CYS A . n A 1 392 ASP 392 446 446 ASP ASP A . n A 1 393 VAL 393 447 447 VAL VAL A . n A 1 394 ILE 394 448 448 ILE ILE A . n A 1 395 TRP 395 449 449 TRP TRP A . n A 1 396 LEU 396 450 450 LEU LEU A . n A 1 397 ASP 397 451 451 ASP ASP A . n A 1 398 ILE 398 452 452 ILE ILE A . n A 1 399 GLU 399 453 453 GLU GLU A . n A 1 400 HIS 400 454 454 HIS HIS A . n A 1 401 ALA 401 455 455 ALA ALA A . n A 1 402 ASP 402 456 456 ASP ASP A . n A 1 403 GLY 403 457 457 GLY GLY A . n A 1 404 LYS 404 458 458 LYS LYS A . n A 1 405 ARG 405 459 459 ARG ARG A . n A 1 406 TYR 406 460 460 TYR TYR A . n A 1 407 PHE 407 461 461 PHE PHE A . n A 1 408 THR 408 462 462 THR THR A . n A 1 409 TRP 409 463 463 TRP TRP A . n A 1 410 ASP 410 464 464 ASP ASP A . n A 1 411 PRO 411 465 465 PRO PRO A . n A 1 412 THR 412 466 466 THR THR A . n A 1 413 ARG 413 467 467 ARG ARG A . n A 1 414 PHE 414 468 468 PHE PHE A . n A 1 415 PRO 415 469 469 PRO PRO A . n A 1 416 GLN 416 470 470 GLN GLN A . n A 1 417 PRO 417 471 471 PRO PRO A . n A 1 418 LEU 418 472 472 LEU LEU A . n A 1 419 ASN 419 473 473 ASN ASN A . n A 1 420 MET 420 474 474 MET MET A . n A 1 421 LEU 421 475 475 LEU LEU A . n A 1 422 GLU 422 476 476 GLU GLU A . n A 1 423 HIS 423 477 477 HIS HIS A . n A 1 424 LEU 424 478 478 LEU LEU A . n A 1 425 ALA 425 479 479 ALA ALA A . n A 1 426 SER 426 480 480 SER SER A . n A 1 427 LYS 427 481 481 LYS LYS A . n A 1 428 ARG 428 482 482 ARG ARG A . n A 1 429 ARG 429 483 483 ARG ARG A . n A 1 430 LYS 430 484 484 LYS LYS A . n A 1 431 LEU 431 485 485 LEU LEU A . n A 1 432 VAL 432 486 486 VAL VAL A . n A 1 433 ALA 433 487 487 ALA ALA A . n A 1 434 ILE 434 488 488 ILE ILE A . n A 1 435 VAL 435 489 489 VAL VAL A . n A 1 436 ASP 436 490 490 ASP ASP A . n A 1 437 PRO 437 491 491 PRO PRO A . n A 1 438 HIS 438 492 492 HIS HIS A . n A 1 439 ILE 439 493 493 ILE ILE A . n A 1 440 LYS 440 494 494 LYS LYS A . n A 1 441 VAL 441 495 495 VAL VAL A . n A 1 442 ASP 442 496 496 ASP ASP A . n A 1 443 SER 443 497 497 SER SER A . n A 1 444 GLY 444 498 498 GLY GLY A . n A 1 445 TYR 445 499 499 TYR TYR A . n A 1 446 ARG 446 500 500 ARG ARG A . n A 1 447 VAL 447 501 501 VAL VAL A . n A 1 448 HIS 448 502 502 HIS HIS A . n A 1 449 GLU 449 503 503 GLU GLU A . n A 1 450 GLU 450 504 504 GLU GLU A . n A 1 451 LEU 451 505 505 LEU LEU A . n A 1 452 ARG 452 506 506 ARG ARG A . n A 1 453 ASN 453 507 507 ASN ASN A . n A 1 454 HIS 454 508 508 HIS HIS A . n A 1 455 GLY 455 509 509 GLY GLY A . n A 1 456 LEU 456 510 510 LEU LEU A . n A 1 457 TYR 457 511 511 TYR TYR A . n A 1 458 VAL 458 512 512 VAL VAL A . n A 1 459 LYS 459 513 513 LYS LYS A . n A 1 460 THR 460 514 514 THR THR A . n A 1 461 ARG 461 515 515 ARG ARG A . n A 1 462 ASP 462 516 516 ASP ASP A . n A 1 463 GLY 463 517 517 GLY GLY A . n A 1 464 SER 464 518 518 SER SER A . n A 1 465 ASP 465 519 519 ASP ASP A . n A 1 466 TYR 466 520 520 TYR TYR A . n A 1 467 GLU 467 521 521 GLU GLU A . n A 1 468 GLY 468 522 522 GLY GLY A . n A 1 469 TRP 469 523 523 TRP TRP A . n A 1 470 CYS 470 524 524 CYS CYS A . n A 1 471 TRP 471 525 525 TRP TRP A . n A 1 472 PRO 472 526 526 PRO PRO A . n A 1 473 GLY 473 527 527 GLY GLY A . n A 1 474 SER 474 528 528 SER SER A . n A 1 475 ALA 475 529 529 ALA ALA A . n A 1 476 SER 476 530 530 SER SER A . n A 1 477 TYR 477 531 531 TYR TYR A . n A 1 478 PRO 478 532 532 PRO PRO A . n A 1 479 ASP 479 533 533 ASP ASP A . n A 1 480 PHE 480 534 534 PHE PHE A . n A 1 481 THR 481 535 535 THR THR A . n A 1 482 ASN 482 536 536 ASN ASN A . n A 1 483 PRO 483 537 537 PRO PRO A . n A 1 484 ARG 484 538 538 ARG ARG A . n A 1 485 MET 485 539 539 MET MET A . n A 1 486 ARG 486 540 540 ARG ARG A . n A 1 487 ALA 487 541 541 ALA ALA A . n A 1 488 TRP 488 542 542 TRP TRP A . n A 1 489 TRP 489 543 543 TRP TRP A . n A 1 490 SER 490 544 544 SER SER A . n A 1 491 ASN 491 545 545 ASN ASN A . n A 1 492 MET 492 546 546 MET MET A . n A 1 493 PHE 493 547 547 PHE PHE A . n A 1 494 SER 494 548 548 SER SER A . n A 1 495 PHE 495 549 549 PHE PHE A . n A 1 496 ASP 496 550 550 ASP ASP A . n A 1 497 ASN 497 551 551 ASN ASN A . n A 1 498 TYR 498 552 552 TYR TYR A . n A 1 499 GLU 499 553 553 GLU GLU A . n A 1 500 GLY 500 554 554 GLY GLY A . n A 1 501 SER 501 555 555 SER SER A . n A 1 502 ALA 502 556 556 ALA ALA A . n A 1 503 PRO 503 557 557 PRO PRO A . n A 1 504 ASN 504 558 558 ASN ASN A . n A 1 505 LEU 505 559 559 LEU LEU A . n A 1 506 TYR 506 560 560 TYR TYR A . n A 1 507 VAL 507 561 561 VAL VAL A . n A 1 508 TRP 508 562 562 TRP TRP A . n A 1 509 ASN 509 563 563 ASN ASN A . n A 1 510 ASP 510 564 564 ASP ASP A . n A 1 511 MET 511 565 565 MET MET A . n A 1 512 ASN 512 566 566 ASN ASN A . n A 1 513 GLU 513 567 567 GLU GLU A . n A 1 514 PRO 514 568 568 PRO PRO A . n A 1 515 SER 515 569 569 SER SER A . n A 1 516 VAL 516 570 570 VAL VAL A . n A 1 517 PHE 517 571 571 PHE PHE A . n A 1 518 ASN 518 572 572 ASN ASN A . n A 1 519 GLY 519 573 573 GLY GLY A . n A 1 520 PRO 520 574 574 PRO PRO A . n A 1 521 GLU 521 575 575 GLU GLU A . n A 1 522 VAL 522 576 576 VAL VAL A . n A 1 523 THR 523 577 577 THR THR A . n A 1 524 MET 524 578 578 MET MET A . n A 1 525 LEU 525 579 579 LEU LEU A . n A 1 526 LYS 526 580 580 LYS LYS A . n A 1 527 ASP 527 581 581 ASP ASP A . n A 1 528 ALA 528 582 582 ALA ALA A . n A 1 529 VAL 529 583 583 VAL VAL A . n A 1 530 HIS 530 584 584 HIS HIS A . n A 1 531 TYR 531 585 585 TYR TYR A . n A 1 532 GLY 532 586 586 GLY GLY A . n A 1 533 GLY 533 587 587 GLY GLY A . n A 1 534 TRP 534 588 588 TRP TRP A . n A 1 535 GLU 535 589 589 GLU GLU A . n A 1 536 HIS 536 590 590 HIS HIS A . n A 1 537 ARG 537 591 591 ARG ARG A . n A 1 538 ASP 538 592 592 ASP ASP A . n A 1 539 ILE 539 593 593 ILE ILE A . n A 1 540 HIS 540 594 594 HIS HIS A . n A 1 541 ASN 541 595 595 ASN ASN A . n A 1 542 ILE 542 596 596 ILE ILE A . n A 1 543 TYR 543 597 597 TYR TYR A . n A 1 544 GLY 544 598 598 GLY GLY A . n A 1 545 LEU 545 599 599 LEU LEU A . n A 1 546 TYR 546 600 600 TYR TYR A . n A 1 547 VAL 547 601 601 VAL VAL A . n A 1 548 HIS 548 602 602 HIS HIS A . n A 1 549 MET 549 603 603 MET MET A . n A 1 550 ALA 550 604 604 ALA ALA A . n A 1 551 THR 551 605 605 THR THR A . n A 1 552 ALA 552 606 606 ALA ALA A . n A 1 553 ASP 553 607 607 ASP ASP A . n A 1 554 GLY 554 608 608 GLY GLY A . n A 1 555 LEU 555 609 609 LEU LEU A . n A 1 556 ILE 556 610 610 ILE ILE A . n A 1 557 GLN 557 611 611 GLN GLN A . n A 1 558 ARG 558 612 612 ARG ARG A . n A 1 559 SER 559 613 613 SER SER A . n A 1 560 GLY 560 614 614 GLY GLY A . n A 1 561 GLY 561 615 615 GLY GLY A . n A 1 562 ILE 562 616 616 ILE ILE A . n A 1 563 GLU 563 617 617 GLU GLU A . n A 1 564 ARG 564 618 618 ARG ARG A . n A 1 565 PRO 565 619 619 PRO PRO A . n A 1 566 PHE 566 620 620 PHE PHE A . n A 1 567 VAL 567 621 621 VAL VAL A . n A 1 568 LEU 568 622 622 LEU LEU A . n A 1 569 SER 569 623 623 SER SER A . n A 1 570 ARG 570 624 624 ARG ARG A . n A 1 571 ALA 571 625 625 ALA ALA A . n A 1 572 PHE 572 626 626 PHE PHE A . n A 1 573 PHE 573 627 627 PHE PHE A . n A 1 574 SER 574 628 628 SER SER A . n A 1 575 GLY 575 629 629 GLY GLY A . n A 1 576 SER 576 630 630 SER SER A . n A 1 577 GLN 577 631 631 GLN GLN A . n A 1 578 ARG 578 632 632 ARG ARG A . n A 1 579 PHE 579 633 633 PHE PHE A . n A 1 580 GLY 580 634 634 GLY GLY A . n A 1 581 ALA 581 635 635 ALA ALA A . n A 1 582 VAL 582 636 636 VAL VAL A . n A 1 583 TRP 583 637 637 TRP TRP A . n A 1 584 THR 584 638 638 THR THR A . n A 1 585 GLY 585 639 639 GLY GLY A . n A 1 586 ASP 586 640 640 ASP ASP A . n A 1 587 ASN 587 641 641 ASN ASN A . n A 1 588 THR 588 642 642 THR THR A . n A 1 589 ALA 589 643 643 ALA ALA A . n A 1 590 GLU 590 644 644 GLU GLU A . n A 1 591 TRP 591 645 645 TRP TRP A . n A 1 592 ASP 592 646 646 ASP ASP A . n A 1 593 HIS 593 647 647 HIS HIS A . n A 1 594 LEU 594 648 648 LEU LEU A . n A 1 595 LYS 595 649 649 LYS LYS A . n A 1 596 ILE 596 650 650 ILE ILE A . n A 1 597 SER 597 651 651 SER SER A . n A 1 598 ILE 598 652 652 ILE ILE A . n A 1 599 PRO 599 653 653 PRO PRO A . n A 1 600 MET 600 654 654 MET MET A . n A 1 601 CYS 601 655 655 CYS CYS A . n A 1 602 LEU 602 656 656 LEU LEU A . n A 1 603 SER 603 657 657 SER SER A . n A 1 604 LEU 604 658 658 LEU LEU A . n A 1 605 ALA 605 659 659 ALA ALA A . n A 1 606 LEU 606 660 660 LEU LEU A . n A 1 607 VAL 607 661 661 VAL VAL A . n A 1 608 GLY 608 662 662 GLY GLY A . n A 1 609 LEU 609 663 663 LEU LEU A . n A 1 610 SER 610 664 664 SER SER A . n A 1 611 PHE 611 665 665 PHE PHE A . n A 1 612 CYS 612 666 666 CYS CYS A . n A 1 613 GLY 613 667 667 GLY GLY A . n A 1 614 ALA 614 668 668 ALA ALA A . n A 1 615 ASP 615 669 669 ASP ASP A . n A 1 616 VAL 616 670 670 VAL VAL A . n A 1 617 GLY 617 671 671 GLY GLY A . n A 1 618 GLY 618 672 672 GLY GLY A . n A 1 619 PHE 619 673 673 PHE PHE A . n A 1 620 PHE 620 674 674 PHE PHE A . n A 1 621 LYS 621 675 675 LYS LYS A . n A 1 622 ASN 622 676 676 ASN ASN A . n A 1 623 PRO 623 677 677 PRO PRO A . n A 1 624 GLU 624 678 678 GLU GLU A . n A 1 625 PRO 625 679 679 PRO PRO A . n A 1 626 GLU 626 680 680 GLU GLU A . n A 1 627 LEU 627 681 681 LEU LEU A . n A 1 628 LEU 628 682 682 LEU LEU A . n A 1 629 VAL 629 683 683 VAL VAL A . n A 1 630 ARG 630 684 684 ARG ARG A . n A 1 631 TRP 631 685 685 TRP TRP A . n A 1 632 TYR 632 686 686 TYR TYR A . n A 1 633 GLN 633 687 687 GLN GLN A . n A 1 634 MET 634 688 688 MET MET A . n A 1 635 GLY 635 689 689 GLY GLY A . n A 1 636 ALA 636 690 690 ALA ALA A . n A 1 637 TYR 637 691 691 TYR TYR A . n A 1 638 GLN 638 692 692 GLN GLN A . n A 1 639 PRO 639 693 693 PRO PRO A . n A 1 640 PHE 640 694 694 PHE PHE A . n A 1 641 PHE 641 695 695 PHE PHE A . n A 1 642 ARG 642 696 696 ARG ARG A . n A 1 643 ALA 643 697 697 ALA ALA A . n A 1 644 HIS 644 698 698 HIS HIS A . n A 1 645 ALA 645 699 699 ALA ALA A . n A 1 646 HIS 646 700 700 HIS HIS A . n A 1 647 LEU 647 701 701 LEU LEU A . n A 1 648 ASP 648 702 702 ASP ASP A . n A 1 649 THR 649 703 703 THR THR A . n A 1 650 GLY 650 704 704 GLY GLY A . n A 1 651 ARG 651 705 705 ARG ARG A . n A 1 652 ARG 652 706 706 ARG ARG A . n A 1 653 GLU 653 707 707 GLU GLU A . n A 1 654 PRO 654 708 708 PRO PRO A . n A 1 655 TRP 655 709 709 TRP TRP A . n A 1 656 LEU 656 710 710 LEU LEU A . n A 1 657 LEU 657 711 711 LEU LEU A . n A 1 658 ALA 658 712 712 ALA ALA A . n A 1 659 SER 659 713 713 SER SER A . n A 1 660 GLN 660 714 714 GLN GLN A . n A 1 661 TYR 661 715 715 TYR TYR A . n A 1 662 GLN 662 716 716 GLN GLN A . n A 1 663 ASP 663 717 717 ASP ASP A . n A 1 664 ALA 664 718 718 ALA ALA A . n A 1 665 ILE 665 719 719 ILE ILE A . n A 1 666 ARG 666 720 720 ARG ARG A . n A 1 667 ASP 667 721 721 ASP ASP A . n A 1 668 ALA 668 722 722 ALA ALA A . n A 1 669 LEU 669 723 723 LEU LEU A . n A 1 670 PHE 670 724 724 PHE PHE A . n A 1 671 GLN 671 725 725 GLN GLN A . n A 1 672 ARG 672 726 726 ARG ARG A . n A 1 673 TYR 673 727 727 TYR TYR A . n A 1 674 SER 674 728 728 SER SER A . n A 1 675 LEU 675 729 729 LEU LEU A . n A 1 676 LEU 676 730 730 LEU LEU A . n A 1 677 PRO 677 731 731 PRO PRO A . n A 1 678 PHE 678 732 732 PHE PHE A . n A 1 679 TRP 679 733 733 TRP TRP A . n A 1 680 TYR 680 734 734 TYR TYR A . n A 1 681 THR 681 735 735 THR THR A . n A 1 682 LEU 682 736 736 LEU LEU A . n A 1 683 PHE 683 737 737 PHE PHE A . n A 1 684 TYR 684 738 738 TYR TYR A . n A 1 685 GLN 685 739 739 GLN GLN A . n A 1 686 ALA 686 740 740 ALA ALA A . n A 1 687 HIS 687 741 741 HIS HIS A . n A 1 688 LYS 688 742 742 LYS LYS A . n A 1 689 GLU 689 743 743 GLU GLU A . n A 1 690 GLY 690 744 744 GLY GLY A . n A 1 691 PHE 691 745 745 PHE PHE A . n A 1 692 PRO 692 746 746 PRO PRO A . n A 1 693 VAL 693 747 747 VAL VAL A . n A 1 694 MET 694 748 748 MET MET A . n A 1 695 ARG 695 749 749 ARG ARG A . n A 1 696 PRO 696 750 750 PRO PRO A . n A 1 697 LEU 697 751 751 LEU LEU A . n A 1 698 TRP 698 752 752 TRP TRP A . n A 1 699 VAL 699 753 753 VAL VAL A . n A 1 700 GLN 700 754 754 GLN GLN A . n A 1 701 TYR 701 755 755 TYR TYR A . n A 1 702 PRO 702 756 756 PRO PRO A . n A 1 703 GLU 703 757 757 GLU GLU A . n A 1 704 ASP 704 758 758 ASP ASP A . n A 1 705 MET 705 759 759 MET MET A . n A 1 706 SER 706 760 760 SER SER A . n A 1 707 THR 707 761 761 THR THR A . n A 1 708 PHE 708 762 762 PHE PHE A . n A 1 709 SER 709 763 763 SER SER A . n A 1 710 ILE 710 764 764 ILE ILE A . n A 1 711 GLU 711 765 765 GLU GLU A . n A 1 712 ASP 712 766 766 ASP ASP A . n A 1 713 GLN 713 767 767 GLN GLN A . n A 1 714 PHE 714 768 768 PHE PHE A . n A 1 715 MET 715 769 769 MET MET A . n A 1 716 LEU 716 770 770 LEU LEU A . n A 1 717 GLY 717 771 771 GLY GLY A . n A 1 718 ASP 718 772 772 ASP ASP A . n A 1 719 ALA 719 773 773 ALA ALA A . n A 1 720 LEU 720 774 774 LEU LEU A . n A 1 721 LEU 721 775 775 LEU LEU A . n A 1 722 ILE 722 776 776 ILE ILE A . n A 1 723 HIS 723 777 777 HIS HIS A . n A 1 724 PRO 724 778 778 PRO PRO A . n A 1 725 VAL 725 779 779 VAL VAL A . n A 1 726 SER 726 780 780 SER SER A . n A 1 727 ASP 727 781 781 ASP ASP A . n A 1 728 ALA 728 782 782 ALA ALA A . n A 1 729 GLY 729 783 783 GLY GLY A . n A 1 730 ALA 730 784 784 ALA ALA A . n A 1 731 HIS 731 785 785 HIS HIS A . n A 1 732 GLY 732 786 786 GLY GLY A . n A 1 733 VAL 733 787 787 VAL VAL A . n A 1 734 GLN 734 788 788 GLN GLN A . n A 1 735 VAL 735 789 789 VAL VAL A . n A 1 736 TYR 736 790 790 TYR TYR A . n A 1 737 LEU 737 791 791 LEU LEU A . n A 1 738 PRO 738 792 792 PRO PRO A . n A 1 739 GLY 739 793 793 GLY GLY A . n A 1 740 GLN 740 794 794 GLN GLN A . n A 1 741 GLU 741 795 795 GLU GLU A . n A 1 742 GLU 742 796 796 GLU GLU A . n A 1 743 VAL 743 797 797 VAL VAL A . n A 1 744 TRP 744 798 798 TRP TRP A . n A 1 745 TYR 745 799 799 TYR TYR A . n A 1 746 ASP 746 800 800 ASP ASP A . n A 1 747 ILE 747 801 801 ILE ILE A . n A 1 748 GLN 748 802 802 GLN GLN A . n A 1 749 SER 749 803 803 SER SER A . n A 1 750 TYR 750 804 804 TYR TYR A . n A 1 751 GLN 751 805 805 GLN GLN A . n A 1 752 LYS 752 806 806 LYS LYS A . n A 1 753 HIS 753 807 807 HIS HIS A . n A 1 754 HIS 754 808 808 HIS HIS A . n A 1 755 GLY 755 809 809 GLY GLY A . n A 1 756 PRO 756 810 810 PRO PRO A . n A 1 757 GLN 757 811 811 GLN GLN A . n A 1 758 THR 758 812 812 THR THR A . n A 1 759 LEU 759 813 813 LEU LEU A . n A 1 760 TYR 760 814 814 TYR TYR A . n A 1 761 LEU 761 815 815 LEU LEU A . n A 1 762 PRO 762 816 816 PRO PRO A . n A 1 763 VAL 763 817 817 VAL VAL A . n A 1 764 THR 764 818 818 THR THR A . n A 1 765 LEU 765 819 819 LEU LEU A . n A 1 766 SER 766 820 820 SER SER A . n A 1 767 SER 767 821 821 SER SER A . n A 1 768 ILE 768 822 822 ILE ILE A . n A 1 769 PRO 769 823 823 PRO PRO A . n A 1 770 VAL 770 824 824 VAL VAL A . n A 1 771 PHE 771 825 825 PHE PHE A . n A 1 772 GLN 772 826 826 GLN GLN A . n A 1 773 ARG 773 827 827 ARG ARG A . n A 1 774 GLY 774 828 828 GLY GLY A . n A 1 775 GLY 775 829 829 GLY GLY A . n A 1 776 THR 776 830 830 THR THR A . n A 1 777 ILE 777 831 831 ILE ILE A . n A 1 778 VAL 778 832 832 VAL VAL A . n A 1 779 PRO 779 833 833 PRO PRO A . n A 1 780 ARG 780 834 834 ARG ARG A . n A 1 781 TRP 781 835 835 TRP TRP A . n A 1 782 MET 782 836 836 MET MET A . n A 1 783 ARG 783 837 837 ARG ARG A . n A 1 784 VAL 784 838 838 VAL VAL A . n A 1 785 ARG 785 839 839 ARG ARG A . n A 1 786 ARG 786 840 840 ARG ARG A . n A 1 787 SER 787 841 841 SER SER A . n A 1 788 SER 788 842 842 SER SER A . n A 1 789 ASP 789 843 843 ASP ASP A . n A 1 790 CYS 790 844 844 CYS CYS A . n A 1 791 MET 791 845 845 MET MET A . n A 1 792 LYS 792 846 846 LYS LYS A . n A 1 793 ASP 793 847 847 ASP ASP A . n A 1 794 ASP 794 848 848 ASP ASP A . n A 1 795 PRO 795 849 849 PRO PRO A . n A 1 796 ILE 796 850 850 ILE ILE A . n A 1 797 THR 797 851 851 THR THR A . n A 1 798 LEU 798 852 852 LEU LEU A . n A 1 799 PHE 799 853 853 PHE PHE A . n A 1 800 VAL 800 854 854 VAL VAL A . n A 1 801 ALA 801 855 855 ALA ALA A . n A 1 802 LEU 802 856 856 LEU LEU A . n A 1 803 SER 803 857 857 SER SER A . n A 1 804 PRO 804 858 858 PRO PRO A . n A 1 805 GLN 805 859 859 GLN GLN A . n A 1 806 GLY 806 860 860 GLY GLY A . n A 1 807 THR 807 861 861 THR THR A . n A 1 808 ALA 808 862 862 ALA ALA A . n A 1 809 GLN 809 863 863 GLN GLN A . n A 1 810 GLY 810 864 864 GLY GLY A . n A 1 811 GLU 811 865 865 GLU GLU A . n A 1 812 LEU 812 866 866 LEU LEU A . n A 1 813 PHE 813 867 867 PHE PHE A . n A 1 814 LEU 814 868 868 LEU LEU A . n A 1 815 ASP 815 869 869 ASP ASP A . n A 1 816 ASP 816 870 870 ASP ASP A . n A 1 817 GLY 817 871 871 GLY GLY A . n A 1 818 HIS 818 872 872 HIS HIS A . n A 1 819 THR 819 873 873 THR THR A . n A 1 820 PHE 820 874 874 PHE PHE A . n A 1 821 ASN 821 875 875 ASN ASN A . n A 1 822 TYR 822 876 876 TYR TYR A . n A 1 823 GLN 823 877 877 GLN GLN A . n A 1 824 THR 824 878 878 THR THR A . n A 1 825 ARG 825 879 879 ARG ARG A . n A 1 826 HIS 826 880 880 HIS HIS A . n A 1 827 GLU 827 881 881 GLU GLU A . n A 1 828 PHE 828 882 882 PHE PHE A . n A 1 829 LEU 829 883 883 LEU LEU A . n A 1 830 LEU 830 884 884 LEU LEU A . n A 1 831 ARG 831 885 885 ARG ARG A . n A 1 832 ARG 832 886 886 ARG ARG A . n A 1 833 PHE 833 887 887 PHE PHE A . n A 1 834 SER 834 888 888 SER SER A . n A 1 835 PHE 835 889 889 PHE PHE A . n A 1 836 SER 836 890 890 SER SER A . n A 1 837 GLY 837 891 891 GLY GLY A . n A 1 838 SER 838 892 892 SER SER A . n A 1 839 THR 839 893 893 THR THR A . n A 1 840 LEU 840 894 894 LEU LEU A . n A 1 841 VAL 841 895 895 VAL VAL A . n A 1 842 SER 842 896 896 SER SER A . n A 1 843 SER 843 897 897 SER SER A . n A 1 844 SER 844 898 898 SER SER A . n A 1 845 ALA 845 899 899 ALA ALA A . n A 1 846 ASP 846 900 900 ASP ASP A . n A 1 847 PRO 847 901 901 PRO PRO A . n A 1 848 LYS 848 902 902 LYS LYS A . n A 1 849 GLY 849 903 903 GLY GLY A . n A 1 850 HIS 850 904 904 HIS HIS A . n A 1 851 LEU 851 905 905 LEU LEU A . n A 1 852 GLU 852 906 906 GLU GLU A . n A 1 853 THR 853 907 907 THR THR A . n A 1 854 PRO 854 908 908 PRO PRO A . n A 1 855 ILE 855 909 909 ILE ILE A . n A 1 856 TRP 856 910 910 TRP TRP A . n A 1 857 ILE 857 911 911 ILE ILE A . n A 1 858 GLU 858 912 912 GLU GLU A . n A 1 859 ARG 859 913 913 ARG ARG A . n A 1 860 VAL 860 914 914 VAL VAL A . n A 1 861 VAL 861 915 915 VAL VAL A . n A 1 862 ILE 862 916 916 ILE ILE A . n A 1 863 MET 863 917 917 MET MET A . n A 1 864 GLY 864 918 918 GLY GLY A . n A 1 865 ALA 865 919 919 ALA ALA A . n A 1 866 GLY 866 920 920 GLY GLY A . n A 1 867 LYS 867 921 921 LYS LYS A . n A 1 868 PRO 868 922 922 PRO PRO A . n A 1 869 ALA 869 923 923 ALA ALA A . n A 1 870 ALA 870 924 924 ALA ALA A . n A 1 871 VAL 871 925 925 VAL VAL A . n A 1 872 VAL 872 926 926 VAL VAL A . n A 1 873 LEU 873 927 927 LEU LEU A . n A 1 874 GLN 874 928 928 GLN GLN A . n A 1 875 THR 875 929 929 THR THR A . n A 1 876 LYS 876 930 930 LYS LYS A . n A 1 877 GLY 877 931 931 GLY GLY A . n A 1 878 SER 878 932 932 SER SER A . n A 1 879 PRO 879 933 933 PRO PRO A . n A 1 880 GLU 880 934 934 GLU GLU A . n A 1 881 SER 881 935 935 SER SER A . n A 1 882 ARG 882 936 936 ARG ARG A . n A 1 883 LEU 883 937 937 LEU LEU A . n A 1 884 SER 884 938 938 SER SER A . n A 1 885 PHE 885 939 939 PHE PHE A . n A 1 886 GLN 886 940 940 GLN GLN A . n A 1 887 HIS 887 941 941 HIS HIS A . n A 1 888 ASP 888 942 942 ASP ASP A . n A 1 889 PRO 889 943 943 PRO PRO A . n A 1 890 GLU 890 944 944 GLU GLU A . n A 1 891 THR 891 945 945 THR THR A . n A 1 892 SER 892 946 946 SER SER A . n A 1 893 VAL 893 947 947 VAL VAL A . n A 1 894 LEU 894 948 948 LEU LEU A . n A 1 895 ILE 895 949 949 ILE ILE A . n A 1 896 LEU 896 950 950 LEU LEU A . n A 1 897 ARG 897 951 951 ARG ARG A . n A 1 898 LYS 898 952 952 LYS LYS A . n A 1 899 PRO 899 953 953 PRO PRO A . n A 1 900 GLY 900 954 954 GLY GLY A . n A 1 901 VAL 901 955 955 VAL VAL A . n A 1 902 SER 902 956 956 SER SER A . n A 1 903 VAL 903 957 957 VAL VAL A . n A 1 904 ALA 904 958 958 ALA ALA A . n A 1 905 SER 905 959 959 SER SER A . n A 1 906 ASP 906 960 960 ASP ASP A . n A 1 907 TRP 907 961 961 TRP TRP A . n A 1 908 SER 908 962 962 SER SER A . n A 1 909 ILE 909 963 963 ILE ILE A . n A 1 910 HIS 910 964 964 HIS HIS A . n A 1 911 LEU 911 965 965 LEU LEU A . n A 1 912 ARG 912 966 966 ARG ARG A . n A 1 913 ALA 913 967 967 ALA ALA A . n B 2 1 PHE 1 30 30 PHE PHE B . n B 2 2 TYR 2 31 31 TYR TYR B . n B 2 3 GLU 3 32 32 GLU GLU B . n B 2 4 GLU 4 33 33 GLU GLU B . n B 2 5 SER 5 34 34 SER SER B . n B 2 6 LYS 6 35 35 LYS LYS B . n B 2 7 PRO 7 36 36 PRO PRO B . n B 2 8 PHE 8 37 37 PHE PHE B . n B 2 9 THR 9 38 38 THR THR B . n B 2 10 CYS 10 39 39 CYS CYS B . n B 2 11 LEU 11 40 40 LEU LEU B . n B 2 12 ASP 12 41 41 ASP ASP B . n B 2 13 GLY 13 42 42 GLY GLY B . n B 2 14 THR 14 43 43 THR THR B . n B 2 15 ALA 15 44 44 ALA ALA B . n B 2 16 THR 16 45 45 THR THR B . n B 2 17 ILE 17 46 46 ILE ILE B . n B 2 18 PRO 18 47 47 PRO PRO B . n B 2 19 PHE 19 48 48 PHE PHE B . n B 2 20 ASP 20 49 49 ASP ASP B . n B 2 21 GLN 21 50 50 GLN GLN B . n B 2 22 VAL 22 51 51 VAL VAL B . n B 2 23 ASN 23 52 52 ASN ASN B . n B 2 24 ASP 24 53 53 ASP ASP B . n B 2 25 ASP 25 54 54 ASP ASP B . n B 2 26 TYR 26 55 55 TYR TYR B . n B 2 27 CYS 27 56 56 CYS CYS B . n B 2 28 ASP 28 57 57 ASP ASP B . n B 2 29 CYS 29 58 58 CYS CYS B . n B 2 30 LYS 30 59 59 LYS LYS B . n B 2 31 ASP 31 60 60 ASP ASP B . n B 2 32 GLY 32 61 61 GLY GLY B . n B 2 33 SER 33 62 62 SER SER B . n B 2 34 ASP 34 63 63 ASP ASP B . n B 2 35 GLU 35 64 64 GLU GLU B . n B 2 36 PRO 36 65 65 PRO PRO B . n B 2 37 GLY 37 66 66 GLY GLY B . n B 2 38 THR 38 67 67 THR THR B . n B 2 39 ALA 39 68 68 ALA ALA B . n B 2 40 ALA 40 69 69 ALA ALA B . n B 2 41 CYS 41 70 70 CYS CYS B . n B 2 42 PRO 42 71 71 PRO PRO B . n B 2 43 ASN 43 72 72 ASN ASN B . n B 2 44 GLY 44 73 73 GLY GLY B . n B 2 45 SER 45 74 74 SER SER B . n B 2 46 PHE 46 75 75 PHE PHE B . n B 2 47 HIS 47 76 76 HIS HIS B . n B 2 48 CYS 48 77 77 CYS CYS B . n B 2 49 THR 49 78 78 THR THR B . n B 2 50 ASN 50 79 79 ASN ASN B . n B 2 51 THR 51 80 80 THR THR B . n B 2 52 GLY 52 81 81 GLY GLY B . n B 2 53 TYR 53 82 82 TYR TYR B . n B 2 54 LYS 54 83 83 LYS LYS B . n B 2 55 PRO 55 84 84 PRO PRO B . n B 2 56 LEU 56 85 85 LEU LEU B . n B 2 57 TYR 57 86 86 TYR TYR B . n B 2 58 ILE 58 87 87 ILE ILE B . n B 2 59 LEU 59 88 88 LEU LEU B . n B 2 60 SER 60 89 89 SER SER B . n B 2 61 SER 61 90 90 SER SER B . n B 2 62 ARG 62 91 91 ARG ARG B . n B 2 63 VAL 63 92 92 VAL VAL B . n B 2 64 ASN 64 93 93 ASN ASN B . n B 2 65 ASP 65 94 94 ASP ASP B . n B 2 66 GLY 66 95 95 GLY GLY B . n B 2 67 VAL 67 96 96 VAL VAL B . n B 2 68 CYS 68 97 97 CYS CYS B . n B 2 69 ASP 69 98 98 ASP ASP B . n B 2 70 CYS 70 99 99 CYS CYS B . n B 2 71 CYS 71 100 100 CYS CYS B . n B 2 72 ASP 72 101 101 ASP ASP B . n B 2 73 GLY 73 102 102 GLY GLY B . n B 2 74 THR 74 103 103 THR THR B . n B 2 75 ASP 75 104 104 ASP ASP B . n B 2 76 GLU 76 105 105 GLU GLU B . n B 2 77 TYR 77 106 106 TYR TYR B . n B 2 78 ASN 78 107 107 ASN ASN B . n B 2 79 SER 79 108 108 SER SER B . n B 2 80 GLY 80 109 109 GLY GLY B . n B 2 81 THR 81 110 110 THR THR B . n B 2 82 VAL 82 111 111 VAL VAL B . n B 2 83 CYS 83 112 112 CYS CYS B . n B 2 84 GLU 84 113 113 GLU GLU B . n B 2 85 ASN 85 114 114 ASN ASN B . n B 2 86 THR 86 115 115 THR THR B . n B 2 87 CYS 87 116 116 CYS CYS B . n B 2 88 ARG 88 117 117 ARG ARG B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 3 NAG 1 1001 1 NAG NAG A . D 3 NAG 2 1002 2 NAG NAG A . E 4 FMT 1 1003 14 FMT FMT A . F 5 ACT 1 1004 15 ACT ACT A . G 6 NBV 1 1005 997 NBV NBV A . H 7 P6G 1 1006 9 P6G P6G A . I 7 P6G 1 1007 10 P6G P6G A . J 8 CA 1 201 998 CA CA B . K 8 CA 1 202 999 CA CA B . L 9 HOH 1 1101 338 HOH HOH A . L 9 HOH 2 1102 114 HOH HOH A . L 9 HOH 3 1103 339 HOH HOH A . L 9 HOH 4 1104 24 HOH HOH A . L 9 HOH 5 1105 123 HOH HOH A . L 9 HOH 6 1106 40 HOH HOH A . L 9 HOH 7 1107 115 HOH HOH A . L 9 HOH 8 1108 131 HOH HOH A . L 9 HOH 9 1109 254 HOH HOH A . L 9 HOH 10 1110 89 HOH HOH A . L 9 HOH 11 1111 164 HOH HOH A . L 9 HOH 12 1112 53 HOH HOH A . L 9 HOH 13 1113 15 HOH HOH A . L 9 HOH 14 1114 261 HOH HOH A . L 9 HOH 15 1115 175 HOH HOH A . L 9 HOH 16 1116 25 HOH HOH A . L 9 HOH 17 1117 139 HOH HOH A . L 9 HOH 18 1118 153 HOH HOH A . L 9 HOH 19 1119 204 HOH HOH A . L 9 HOH 20 1120 39 HOH HOH A . L 9 HOH 21 1121 120 HOH HOH A . L 9 HOH 22 1122 129 HOH HOH A . L 9 HOH 23 1123 116 HOH HOH A . L 9 HOH 24 1124 126 HOH HOH A . L 9 HOH 25 1125 206 HOH HOH A . L 9 HOH 26 1126 22 HOH HOH A . L 9 HOH 27 1127 255 HOH HOH A . L 9 HOH 28 1128 79 HOH HOH A . L 9 HOH 29 1129 13 HOH HOH A . L 9 HOH 30 1130 215 HOH HOH A . L 9 HOH 31 1131 240 HOH HOH A . L 9 HOH 32 1132 16 HOH HOH A . L 9 HOH 33 1133 308 HOH HOH A . L 9 HOH 34 1134 159 HOH HOH A . L 9 HOH 35 1135 222 HOH HOH A . L 9 HOH 36 1136 87 HOH HOH A . L 9 HOH 37 1137 160 HOH HOH A . L 9 HOH 38 1138 68 HOH HOH A . L 9 HOH 39 1139 210 HOH HOH A . L 9 HOH 40 1140 245 HOH HOH A . L 9 HOH 41 1141 59 HOH HOH A . L 9 HOH 42 1142 30 HOH HOH A . L 9 HOH 43 1143 317 HOH HOH A . L 9 HOH 44 1144 209 HOH HOH A . L 9 HOH 45 1145 4 HOH HOH A . L 9 HOH 46 1146 119 HOH HOH A . L 9 HOH 47 1147 232 HOH HOH A . L 9 HOH 48 1148 212 HOH HOH A . L 9 HOH 49 1149 37 HOH HOH A . L 9 HOH 50 1150 52 HOH HOH A . L 9 HOH 51 1151 121 HOH HOH A . L 9 HOH 52 1152 104 HOH HOH A . L 9 HOH 53 1153 81 HOH HOH A . L 9 HOH 54 1154 156 HOH HOH A . L 9 HOH 55 1155 82 HOH HOH A . L 9 HOH 56 1156 43 HOH HOH A . L 9 HOH 57 1157 163 HOH HOH A . L 9 HOH 58 1158 247 HOH HOH A . L 9 HOH 59 1159 246 HOH HOH A . L 9 HOH 60 1160 196 HOH HOH A . L 9 HOH 61 1161 94 HOH HOH A . L 9 HOH 62 1162 289 HOH HOH A . L 9 HOH 63 1163 46 HOH HOH A . L 9 HOH 64 1164 3 HOH HOH A . L 9 HOH 65 1165 50 HOH HOH A . L 9 HOH 66 1166 109 HOH HOH A . L 9 HOH 67 1167 284 HOH HOH A . L 9 HOH 68 1168 102 HOH HOH A . L 9 HOH 69 1169 107 HOH HOH A . L 9 HOH 70 1170 285 HOH HOH A . L 9 HOH 71 1171 256 HOH HOH A . L 9 HOH 72 1172 303 HOH HOH A . L 9 HOH 73 1173 85 HOH HOH A . L 9 HOH 74 1174 208 HOH HOH A . L 9 HOH 75 1175 327 HOH HOH A . L 9 HOH 76 1176 29 HOH HOH A . L 9 HOH 77 1177 239 HOH HOH A . L 9 HOH 78 1178 45 HOH HOH A . L 9 HOH 79 1179 337 HOH HOH A . L 9 HOH 80 1180 169 HOH HOH A . L 9 HOH 81 1181 298 HOH HOH A . L 9 HOH 82 1182 55 HOH HOH A . L 9 HOH 83 1183 188 HOH HOH A . L 9 HOH 84 1184 19 HOH HOH A . L 9 HOH 85 1185 248 HOH HOH A . L 9 HOH 86 1186 165 HOH HOH A . L 9 HOH 87 1187 193 HOH HOH A . L 9 HOH 88 1188 48 HOH HOH A . L 9 HOH 89 1189 77 HOH HOH A . L 9 HOH 90 1190 6 HOH HOH A . L 9 HOH 91 1191 122 HOH HOH A . L 9 HOH 92 1192 8 HOH HOH A . L 9 HOH 93 1193 23 HOH HOH A . L 9 HOH 94 1194 155 HOH HOH A . L 9 HOH 95 1195 51 HOH HOH A . L 9 HOH 96 1196 167 HOH HOH A . L 9 HOH 97 1197 9 HOH HOH A . L 9 HOH 98 1198 20 HOH HOH A . L 9 HOH 99 1199 309 HOH HOH A . L 9 HOH 100 1200 10 HOH HOH A . L 9 HOH 101 1201 47 HOH HOH A . L 9 HOH 102 1202 11 HOH HOH A . L 9 HOH 103 1203 2 HOH HOH A . L 9 HOH 104 1204 106 HOH HOH A . L 9 HOH 105 1205 21 HOH HOH A . L 9 HOH 106 1206 33 HOH HOH A . L 9 HOH 107 1207 35 HOH HOH A . L 9 HOH 108 1208 105 HOH HOH A . L 9 HOH 109 1209 242 HOH HOH A . L 9 HOH 110 1210 78 HOH HOH A . L 9 HOH 111 1211 182 HOH HOH A . L 9 HOH 112 1212 140 HOH HOH A . L 9 HOH 113 1213 5 HOH HOH A . L 9 HOH 114 1214 66 HOH HOH A . L 9 HOH 115 1215 168 HOH HOH A . L 9 HOH 116 1216 138 HOH HOH A . L 9 HOH 117 1217 291 HOH HOH A . L 9 HOH 118 1218 174 HOH HOH A . L 9 HOH 119 1219 31 HOH HOH A . L 9 HOH 120 1220 279 HOH HOH A . L 9 HOH 121 1221 110 HOH HOH A . L 9 HOH 122 1222 228 HOH HOH A . L 9 HOH 123 1223 17 HOH HOH A . L 9 HOH 124 1224 41 HOH HOH A . L 9 HOH 125 1225 36 HOH HOH A . L 9 HOH 126 1226 269 HOH HOH A . L 9 HOH 127 1227 300 HOH HOH A . L 9 HOH 128 1228 65 HOH HOH A . L 9 HOH 129 1229 173 HOH HOH A . L 9 HOH 130 1230 241 HOH HOH A . L 9 HOH 131 1231 230 HOH HOH A . L 9 HOH 132 1232 211 HOH HOH A . L 9 HOH 133 1233 323 HOH HOH A . L 9 HOH 134 1234 226 HOH HOH A . L 9 HOH 135 1235 34 HOH HOH A . L 9 HOH 136 1236 67 HOH HOH A . L 9 HOH 137 1237 201 HOH HOH A . L 9 HOH 138 1238 97 HOH HOH A . L 9 HOH 139 1239 86 HOH HOH A . L 9 HOH 140 1240 276 HOH HOH A . L 9 HOH 141 1241 124 HOH HOH A . L 9 HOH 142 1242 319 HOH HOH A . L 9 HOH 143 1243 142 HOH HOH A . L 9 HOH 144 1244 178 HOH HOH A . L 9 HOH 145 1245 170 HOH HOH A . L 9 HOH 146 1246 57 HOH HOH A . L 9 HOH 147 1247 224 HOH HOH A . L 9 HOH 148 1248 60 HOH HOH A . L 9 HOH 149 1249 306 HOH HOH A . L 9 HOH 150 1250 192 HOH HOH A . L 9 HOH 151 1251 336 HOH HOH A . L 9 HOH 152 1252 200 HOH HOH A . L 9 HOH 153 1253 218 HOH HOH A . L 9 HOH 154 1254 191 HOH HOH A . L 9 HOH 155 1255 152 HOH HOH A . L 9 HOH 156 1256 286 HOH HOH A . L 9 HOH 157 1257 56 HOH HOH A . L 9 HOH 158 1258 181 HOH HOH A . L 9 HOH 159 1259 75 HOH HOH A . L 9 HOH 160 1260 74 HOH HOH A . L 9 HOH 161 1261 234 HOH HOH A . L 9 HOH 162 1262 54 HOH HOH A . L 9 HOH 163 1263 275 HOH HOH A . L 9 HOH 164 1264 148 HOH HOH A . L 9 HOH 165 1265 299 HOH HOH A . L 9 HOH 166 1266 83 HOH HOH A . L 9 HOH 167 1267 147 HOH HOH A . L 9 HOH 168 1268 238 HOH HOH A . L 9 HOH 169 1269 252 HOH HOH A . L 9 HOH 170 1270 69 HOH HOH A . L 9 HOH 171 1271 100 HOH HOH A . L 9 HOH 172 1272 12 HOH HOH A . L 9 HOH 173 1273 92 HOH HOH A . L 9 HOH 174 1274 267 HOH HOH A . L 9 HOH 175 1275 150 HOH HOH A . L 9 HOH 176 1276 237 HOH HOH A . L 9 HOH 177 1277 171 HOH HOH A . L 9 HOH 178 1278 235 HOH HOH A . L 9 HOH 179 1279 26 HOH HOH A . L 9 HOH 180 1280 161 HOH HOH A . L 9 HOH 181 1281 272 HOH HOH A . L 9 HOH 182 1282 111 HOH HOH A . L 9 HOH 183 1283 73 HOH HOH A . L 9 HOH 184 1284 315 HOH HOH A . L 9 HOH 185 1285 108 HOH HOH A . L 9 HOH 186 1286 141 HOH HOH A . L 9 HOH 187 1287 166 HOH HOH A . L 9 HOH 188 1288 186 HOH HOH A . L 9 HOH 189 1289 117 HOH HOH A . L 9 HOH 190 1290 264 HOH HOH A . L 9 HOH 191 1291 189 HOH HOH A . L 9 HOH 192 1292 38 HOH HOH A . L 9 HOH 193 1293 49 HOH HOH A . L 9 HOH 194 1294 202 HOH HOH A . L 9 HOH 195 1295 113 HOH HOH A . L 9 HOH 196 1296 310 HOH HOH A . L 9 HOH 197 1297 143 HOH HOH A . L 9 HOH 198 1298 101 HOH HOH A . L 9 HOH 199 1299 283 HOH HOH A . L 9 HOH 200 1300 220 HOH HOH A . L 9 HOH 201 1301 270 HOH HOH A . L 9 HOH 202 1302 91 HOH HOH A . L 9 HOH 203 1303 136 HOH HOH A . L 9 HOH 204 1304 61 HOH HOH A . L 9 HOH 205 1305 304 HOH HOH A . L 9 HOH 206 1306 278 HOH HOH A . L 9 HOH 207 1307 137 HOH HOH A . L 9 HOH 208 1308 277 HOH HOH A . L 9 HOH 209 1309 311 HOH HOH A . L 9 HOH 210 1310 268 HOH HOH A . L 9 HOH 211 1311 297 HOH HOH A . L 9 HOH 212 1312 183 HOH HOH A . L 9 HOH 213 1313 44 HOH HOH A . L 9 HOH 214 1314 32 HOH HOH A . L 9 HOH 215 1315 103 HOH HOH A . L 9 HOH 216 1316 198 HOH HOH A . L 9 HOH 217 1317 251 HOH HOH A . L 9 HOH 218 1318 134 HOH HOH A . L 9 HOH 219 1319 135 HOH HOH A . L 9 HOH 220 1320 18 HOH HOH A . L 9 HOH 221 1321 172 HOH HOH A . L 9 HOH 222 1322 63 HOH HOH A . L 9 HOH 223 1323 176 HOH HOH A . L 9 HOH 224 1324 219 HOH HOH A . L 9 HOH 225 1325 243 HOH HOH A . L 9 HOH 226 1326 95 HOH HOH A . L 9 HOH 227 1327 273 HOH HOH A . L 9 HOH 228 1328 90 HOH HOH A . L 9 HOH 229 1329 231 HOH HOH A . L 9 HOH 230 1330 72 HOH HOH A . L 9 HOH 231 1331 225 HOH HOH A . L 9 HOH 232 1332 249 HOH HOH A . L 9 HOH 233 1333 71 HOH HOH A . L 9 HOH 234 1334 180 HOH HOH A . L 9 HOH 235 1335 190 HOH HOH A . L 9 HOH 236 1336 128 HOH HOH A . L 9 HOH 237 1337 96 HOH HOH A . L 9 HOH 238 1338 293 HOH HOH A . L 9 HOH 239 1339 80 HOH HOH A . L 9 HOH 240 1340 250 HOH HOH A . L 9 HOH 241 1341 205 HOH HOH A . L 9 HOH 242 1342 287 HOH HOH A . L 9 HOH 243 1343 149 HOH HOH A . L 9 HOH 244 1344 233 HOH HOH A . L 9 HOH 245 1345 263 HOH HOH A . L 9 HOH 246 1346 331 HOH HOH A . L 9 HOH 247 1347 271 HOH HOH A . L 9 HOH 248 1348 145 HOH HOH A . L 9 HOH 249 1349 322 HOH HOH A . L 9 HOH 250 1350 158 HOH HOH A . L 9 HOH 251 1351 195 HOH HOH A . L 9 HOH 252 1352 1 HOH HOH A . L 9 HOH 253 1353 305 HOH HOH A . L 9 HOH 254 1354 334 HOH HOH A . L 9 HOH 255 1355 266 HOH HOH A . L 9 HOH 256 1356 325 HOH HOH A . L 9 HOH 257 1357 333 HOH HOH A . L 9 HOH 258 1358 274 HOH HOH A . L 9 HOH 259 1359 199 HOH HOH A . L 9 HOH 260 1360 313 HOH HOH A . L 9 HOH 261 1361 177 HOH HOH A . L 9 HOH 262 1362 127 HOH HOH A . L 9 HOH 263 1363 280 HOH HOH A . L 9 HOH 264 1364 221 HOH HOH A . L 9 HOH 265 1365 302 HOH HOH A . L 9 HOH 266 1366 335 HOH HOH A . L 9 HOH 267 1367 281 HOH HOH A . M 9 HOH 1 301 258 HOH HOH B . M 9 HOH 2 302 157 HOH HOH B . M 9 HOH 3 303 58 HOH HOH B . M 9 HOH 4 304 213 HOH HOH B . M 9 HOH 5 305 296 HOH HOH B . M 9 HOH 6 306 295 HOH HOH B . M 9 HOH 7 307 146 HOH HOH B . M 9 HOH 8 308 132 HOH HOH B . M 9 HOH 9 309 62 HOH HOH B . M 9 HOH 10 310 144 HOH HOH B . M 9 HOH 11 311 88 HOH HOH B . M 9 HOH 12 312 236 HOH HOH B . M 9 HOH 13 313 70 HOH HOH B . M 9 HOH 14 314 112 HOH HOH B . M 9 HOH 15 315 197 HOH HOH B . M 9 HOH 16 316 118 HOH HOH B . M 9 HOH 17 317 27 HOH HOH B . M 9 HOH 18 318 133 HOH HOH B . M 9 HOH 19 319 203 HOH HOH B . M 9 HOH 20 320 14 HOH HOH B . M 9 HOH 21 321 260 HOH HOH B . M 9 HOH 22 322 64 HOH HOH B . M 9 HOH 23 323 253 HOH HOH B . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 3830 ? 1 MORE 8 ? 1 'SSA (A^2)' 34450 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 O ? B GLN 21 ? B GLN 50 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OD1 ? B ASP 24 ? B ASP 53 ? 1_555 86.4 ? 2 O ? B GLN 21 ? B GLN 50 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 O ? B TYR 26 ? B TYR 55 ? 1_555 173.5 ? 3 OD1 ? B ASP 24 ? B ASP 53 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 O ? B TYR 26 ? B TYR 55 ? 1_555 89.4 ? 4 O ? B GLN 21 ? B GLN 50 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OD2 ? B ASP 28 ? B ASP 57 ? 1_555 99.1 ? 5 OD1 ? B ASP 24 ? B ASP 53 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OD2 ? B ASP 28 ? B ASP 57 ? 1_555 99.7 ? 6 O ? B TYR 26 ? B TYR 55 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OD2 ? B ASP 28 ? B ASP 57 ? 1_555 86.5 ? 7 O ? B GLN 21 ? B GLN 50 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OD2 ? B ASP 34 ? B ASP 63 ? 1_555 95.8 ? 8 OD1 ? B ASP 24 ? B ASP 53 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OD2 ? B ASP 34 ? B ASP 63 ? 1_555 172.1 ? 9 O ? B TYR 26 ? B TYR 55 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OD2 ? B ASP 34 ? B ASP 63 ? 1_555 87.7 ? 10 OD2 ? B ASP 28 ? B ASP 57 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OD2 ? B ASP 34 ? B ASP 63 ? 1_555 87.5 ? 11 O ? B GLN 21 ? B GLN 50 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OE2 ? B GLU 35 ? B GLU 64 ? 1_555 94.8 ? 12 OD1 ? B ASP 24 ? B ASP 53 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OE2 ? B GLU 35 ? B GLU 64 ? 1_555 79.5 ? 13 O ? B TYR 26 ? B TYR 55 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OE2 ? B GLU 35 ? B GLU 64 ? 1_555 79.5 ? 14 OD2 ? B ASP 28 ? B ASP 57 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OE2 ? B GLU 35 ? B GLU 64 ? 1_555 165.9 ? 15 OD2 ? B ASP 34 ? B ASP 63 ? 1_555 CA ? J CA . ? B CA 201 ? 1_555 OE2 ? B GLU 35 ? B GLU 64 ? 1_555 92.7 ? 16 O ? B ARG 62 ? B ARG 91 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OD1 ? B ASP 65 ? B ASP 94 ? 1_555 85.6 ? 17 O ? B ARG 62 ? B ARG 91 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 O ? B VAL 67 ? B VAL 96 ? 1_555 170.6 ? 18 OD1 ? B ASP 65 ? B ASP 94 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 O ? B VAL 67 ? B VAL 96 ? 1_555 85.0 ? 19 O ? B ARG 62 ? B ARG 91 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OD2 ? B ASP 69 ? B ASP 98 ? 1_555 94.3 ? 20 OD1 ? B ASP 65 ? B ASP 94 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OD2 ? B ASP 69 ? B ASP 98 ? 1_555 96.9 ? 21 O ? B VAL 67 ? B VAL 96 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OD2 ? B ASP 69 ? B ASP 98 ? 1_555 86.4 ? 22 O ? B ARG 62 ? B ARG 91 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OD2 ? B ASP 75 ? B ASP 104 ? 1_555 102.5 ? 23 OD1 ? B ASP 65 ? B ASP 94 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OD2 ? B ASP 75 ? B ASP 104 ? 1_555 170.8 ? 24 O ? B VAL 67 ? B VAL 96 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OD2 ? B ASP 75 ? B ASP 104 ? 1_555 86.9 ? 25 OD2 ? B ASP 69 ? B ASP 98 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OD2 ? B ASP 75 ? B ASP 104 ? 1_555 86.9 ? 26 O ? B ARG 62 ? B ARG 91 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OE2 ? B GLU 76 ? B GLU 105 ? 1_555 94.2 ? 27 OD1 ? B ASP 65 ? B ASP 94 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OE2 ? B GLU 76 ? B GLU 105 ? 1_555 78.7 ? 28 O ? B VAL 67 ? B VAL 96 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OE2 ? B GLU 76 ? B GLU 105 ? 1_555 84.4 ? 29 OD2 ? B ASP 69 ? B ASP 98 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OE2 ? B GLU 76 ? B GLU 105 ? 1_555 170.1 ? 30 OD2 ? B ASP 75 ? B ASP 104 ? 1_555 CA ? K CA . ? B CA 202 ? 1_555 OE2 ? B GLU 76 ? B GLU 105 ? 1_555 96.2 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2016-07-27 2 'Structure model' 1 1 2016-08-03 3 'Structure model' 1 2 2016-08-24 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? BUSTER ? ? ? 2.10.2 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? AutoPROC ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? BUSTER ? ? ? . 4 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 LYS A 96 ? ? 71.46 35.60 2 1 ALA A 143 ? ? 49.30 -119.20 3 1 ASP A 163 ? ? 58.18 -109.13 4 1 TRP A 248 ? ? -107.38 -122.54 5 1 LYS A 253 ? ? 54.43 -117.89 6 1 LYS A 253 ? ? 55.43 -118.61 7 1 LYS A 259 ? ? 39.32 65.27 8 1 ILE A 281 ? ? 35.21 52.13 9 1 LEU A 317 ? ? -101.56 -154.66 10 1 ASP A 427 ? ? -171.24 -179.66 11 1 PRO A 491 ? ? -88.71 39.37 12 1 PHE A 665 ? ? -102.20 74.29 13 1 LYS A 675 ? ? 71.87 175.62 14 1 HIS A 872 ? ? -157.96 -11.33 15 1 ASN B 107 ? ? -153.40 56.43 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A TRP 525 ? CD1 ? A TRP 471 CD1 2 1 Y 1 A TRP 525 ? CD2 ? A TRP 471 CD2 3 1 Y 1 A TRP 525 ? NE1 ? A TRP 471 NE1 4 1 Y 1 A TRP 525 ? CE2 ? A TRP 471 CE2 5 1 Y 1 A TRP 525 ? CE3 ? A TRP 471 CE3 6 1 Y 1 A TRP 525 ? CZ2 ? A TRP 471 CZ2 7 1 Y 1 A TRP 525 ? CZ3 ? A TRP 471 CZ3 8 1 Y 1 A TRP 525 ? CH2 ? A TRP 471 CH2 9 1 Y 1 A ALA 967 ? O ? A ALA 913 O 10 1 N 1 A P6G 1006 ? O1 ? H P6G 1 O1 11 1 N 1 A P6G 1006 ? C2 ? H P6G 1 C2 12 1 N 1 A P6G 1006 ? C17 ? H P6G 1 C17 13 1 N 1 A P6G 1006 ? C18 ? H P6G 1 C18 14 1 N 1 A P6G 1006 ? O19 ? H P6G 1 O19 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A VAL 208 ? A VAL 154 2 1 Y 1 A PRO 209 ? A PRO 155 3 1 Y 1 A GLN 210 ? A GLN 156 4 1 Y 1 A GLU 211 ? A GLU 157 5 1 Y 1 A SER 212 ? A SER 158 6 1 Y 1 A LYS 213 ? A LYS 159 7 1 Y 1 A ASP 214 ? A ASP 160 8 1 Y 1 A PRO 215 ? A PRO 161 9 1 Y 1 A ALA 216 ? A ALA 162 10 1 Y 1 A GLU 217 ? A GLU 163 11 1 Y 1 A GLY 218 ? A GLY 164 12 1 Y 1 A ASN 219 ? A ASN 165 13 1 Y 1 A GLY 220 ? A GLY 166 14 1 Y 1 A ALA 221 ? A ALA 167 15 1 Y 1 A GLN 222 ? A GLN 168 16 1 Y 1 A PRO 223 ? A PRO 169 17 1 Y 1 A GLU 224 ? A GLU 170 18 1 Y 1 A ALA 225 ? A ALA 171 19 1 Y 1 A THR 226 ? A THR 172 20 1 Y 1 A PRO 227 ? A PRO 173 21 1 Y 1 A GLY 228 ? A GLY 174 22 1 Y 1 A ASP 229 ? A ASP 175 23 1 Y 1 A GLY 230 ? A GLY 176 24 1 Y 1 A ASP 231 ? A ASP 177 25 1 Y 1 A LYS 232 ? A LYS 178 26 1 Y 1 A PRO 233 ? A PRO 179 27 1 Y 1 A GLU 234 ? A GLU 180 28 1 Y 1 A GLU 235 ? A GLU 181 29 1 Y 1 A THR 236 ? A THR 182 30 1 Y 1 A GLN 237 ? A GLN 183 31 1 Y 1 A GLU 238 ? A GLU 184 32 1 Y 1 A LYS 239 ? A LYS 185 33 1 Y 1 A ALA 240 ? A ALA 186 34 1 Y 1 A GLU 241 ? A GLU 187 35 1 Y 1 A LYS 242 ? A LYS 188 36 1 Y 1 A ASP 243 ? A ASP 189 37 1 Y 1 A THR 351 ? A THR 297 38 1 Y 1 A ALA 352 ? A ALA 298 39 1 Y 1 A GLY 353 ? A GLY 299 40 1 Y 1 A LYS 354 ? A LYS 300 41 1 Y 1 A THR 355 ? A THR 301 42 1 Y 1 A LEU 356 ? A LEU 302 43 1 Y 1 A PHE 357 ? A PHE 303 44 1 Y 1 A GLY 358 ? A GLY 304 45 1 Y 1 A LYS 359 ? A LYS 305 46 1 Y 1 A MET 360 ? A MET 306 47 1 Y 1 A LEU 361 ? A LEU 307 48 1 Y 1 A ASP 362 ? A ASP 308 49 1 Y 1 A TYR 363 ? A TYR 309 50 1 Y 1 A LEU 364 ? A LEU 310 51 1 Y 1 A GLN 365 ? A GLN 311 52 1 Y 1 A GLY 366 ? A GLY 312 53 1 Y 1 A SER 367 ? A SER 313 54 1 Y 1 A GLY 368 ? A GLY 314 55 1 Y 1 A GLU 369 ? A GLU 315 # _pdbx_audit_support.funding_organization 'Wellcome Trust' _pdbx_audit_support.country 'United Kingdom' _pdbx_audit_support.grant_number 097300/Z/11/Z _pdbx_audit_support.ordinal 1 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 3 N-ACETYL-D-GLUCOSAMINE NAG 4 'FORMIC ACID' FMT 5 'ACETATE ION' ACT 6 '(2R,3R,4R,5S)-1-BUTYL-2-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL' NBV 7 'HEXAETHYLENE GLYCOL' P6G 8 'CALCIUM ION' CA 9 water HOH #