data_5GNB # _entry.id 5GNB # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.284 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5GNB WWPDB D_1300001093 # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5GNB _pdbx_database_status.recvd_initial_deposition_date 2016-07-20 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site PDBJ _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal _audit_author.identifier_ORCID 'Guan, H.' 1 ? 'Wojdyla, J.A.' 2 ? 'Wang, M.' 3 ? 'Cui, S.' 4 ? # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country UK _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Nat Commun' _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 2041-1723 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 8 _citation.language ? _citation.page_first 15216 _citation.page_last 15216 _citation.title 'Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1' _citation.year 2017 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1038/ncomms15216 _citation.pdbx_database_id_PubMed 28534504 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Ou, X.' 1 primary 'Guan, H.' 2 primary 'Qin, B.' 3 primary 'Mu, Z.' 4 primary 'Wojdyla, J.A.' 5 primary 'Wang, M.' 6 primary 'Dominguez, S.R.' 7 primary 'Qian, Z.' 8 primary 'Cui, S.' 9 # _cell.angle_alpha 90.00 _cell.angle_alpha_esd ? _cell.angle_beta 90.00 _cell.angle_beta_esd ? _cell.angle_gamma 90.00 _cell.angle_gamma_esd ? _cell.entry_id 5GNB _cell.details ? _cell.formula_units_Z ? _cell.length_a 86.720 _cell.length_a_esd ? _cell.length_b 183.990 _cell.length_b_esd ? _cell.length_c 63.160 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 8 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 5GNB _symmetry.cell_setting ? _symmetry.Int_Tables_number 20 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'C 2 2 21' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Spike glycoprotein' 41425.062 1 ? ? 'UNP residues 307-677' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 4 ? ? ? ? 3 water nat water 18.015 234 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'S glycoprotein,E2,Peplomer protein' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;SGFTVKPVATVHRRIPDLPDCDIDKWLNNFNVPSPLNWERKIFSNCNFNLSTLLRLVHTDSFSCNNFDESKIYGSCFKSI VLDKFAIPNSRRSDLQLGSSGFLQSSNYKIDTTSSSCQLYYSLPAINVTINNYNPSSWNRRYGFNNFNLSSHSVVYSRYC FSVNNTFCPCAKPSFASSCKSHKPPSASCPIGTNYRSCESTTVLDHTDWCRCSCLPDPITAYDPRSCSQKKSLVGVGEHC AGFGVDEEKCGVLDGSYNVSCLCSTDAFLGWSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDVCVDYDL YGITGQGIFKEVSAVYYNSWQNLLYDSNGNIIGFKDFVTNKTYNIFPCYAG ; _entity_poly.pdbx_seq_one_letter_code_can ;SGFTVKPVATVHRRIPDLPDCDIDKWLNNFNVPSPLNWERKIFSNCNFNLSTLLRLVHTDSFSCNNFDESKIYGSCFKSI VLDKFAIPNSRRSDLQLGSSGFLQSSNYKIDTTSSSCQLYYSLPAINVTINNYNPSSWNRRYGFNNFNLSSHSVVYSRYC FSVNNTFCPCAKPSFASSCKSHKPPSASCPIGTNYRSCESTTVLDHTDWCRCSCLPDPITAYDPRSCSQKKSLVGVGEHC AGFGVDEEKCGVLDGSYNVSCLCSTDAFLGWSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDVCVDYDL YGITGQGIFKEVSAVYYNSWQNLLYDSNGNIIGFKDFVTNKTYNIFPCYAG ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 SER n 1 2 GLY n 1 3 PHE n 1 4 THR n 1 5 VAL n 1 6 LYS n 1 7 PRO n 1 8 VAL n 1 9 ALA n 1 10 THR n 1 11 VAL n 1 12 HIS n 1 13 ARG n 1 14 ARG n 1 15 ILE n 1 16 PRO n 1 17 ASP n 1 18 LEU n 1 19 PRO n 1 20 ASP n 1 21 CYS n 1 22 ASP n 1 23 ILE n 1 24 ASP n 1 25 LYS n 1 26 TRP n 1 27 LEU n 1 28 ASN n 1 29 ASN n 1 30 PHE n 1 31 ASN n 1 32 VAL n 1 33 PRO n 1 34 SER n 1 35 PRO n 1 36 LEU n 1 37 ASN n 1 38 TRP n 1 39 GLU n 1 40 ARG n 1 41 LYS n 1 42 ILE n 1 43 PHE n 1 44 SER n 1 45 ASN n 1 46 CYS n 1 47 ASN n 1 48 PHE n 1 49 ASN n 1 50 LEU n 1 51 SER n 1 52 THR n 1 53 LEU n 1 54 LEU n 1 55 ARG n 1 56 LEU n 1 57 VAL n 1 58 HIS n 1 59 THR n 1 60 ASP n 1 61 SER n 1 62 PHE n 1 63 SER n 1 64 CYS n 1 65 ASN n 1 66 ASN n 1 67 PHE n 1 68 ASP n 1 69 GLU n 1 70 SER n 1 71 LYS n 1 72 ILE n 1 73 TYR n 1 74 GLY n 1 75 SER n 1 76 CYS n 1 77 PHE n 1 78 LYS n 1 79 SER n 1 80 ILE n 1 81 VAL n 1 82 LEU n 1 83 ASP n 1 84 LYS n 1 85 PHE n 1 86 ALA n 1 87 ILE n 1 88 PRO n 1 89 ASN n 1 90 SER n 1 91 ARG n 1 92 ARG n 1 93 SER n 1 94 ASP n 1 95 LEU n 1 96 GLN n 1 97 LEU n 1 98 GLY n 1 99 SER n 1 100 SER n 1 101 GLY n 1 102 PHE n 1 103 LEU n 1 104 GLN n 1 105 SER n 1 106 SER n 1 107 ASN n 1 108 TYR n 1 109 LYS n 1 110 ILE n 1 111 ASP n 1 112 THR n 1 113 THR n 1 114 SER n 1 115 SER n 1 116 SER n 1 117 CYS n 1 118 GLN n 1 119 LEU n 1 120 TYR n 1 121 TYR n 1 122 SER n 1 123 LEU n 1 124 PRO n 1 125 ALA n 1 126 ILE n 1 127 ASN n 1 128 VAL n 1 129 THR n 1 130 ILE n 1 131 ASN n 1 132 ASN n 1 133 TYR n 1 134 ASN n 1 135 PRO n 1 136 SER n 1 137 SER n 1 138 TRP n 1 139 ASN n 1 140 ARG n 1 141 ARG n 1 142 TYR n 1 143 GLY n 1 144 PHE n 1 145 ASN n 1 146 ASN n 1 147 PHE n 1 148 ASN n 1 149 LEU n 1 150 SER n 1 151 SER n 1 152 HIS n 1 153 SER n 1 154 VAL n 1 155 VAL n 1 156 TYR n 1 157 SER n 1 158 ARG n 1 159 TYR n 1 160 CYS n 1 161 PHE n 1 162 SER n 1 163 VAL n 1 164 ASN n 1 165 ASN n 1 166 THR n 1 167 PHE n 1 168 CYS n 1 169 PRO n 1 170 CYS n 1 171 ALA n 1 172 LYS n 1 173 PRO n 1 174 SER n 1 175 PHE n 1 176 ALA n 1 177 SER n 1 178 SER n 1 179 CYS n 1 180 LYS n 1 181 SER n 1 182 HIS n 1 183 LYS n 1 184 PRO n 1 185 PRO n 1 186 SER n 1 187 ALA n 1 188 SER n 1 189 CYS n 1 190 PRO n 1 191 ILE n 1 192 GLY n 1 193 THR n 1 194 ASN n 1 195 TYR n 1 196 ARG n 1 197 SER n 1 198 CYS n 1 199 GLU n 1 200 SER n 1 201 THR n 1 202 THR n 1 203 VAL n 1 204 LEU n 1 205 ASP n 1 206 HIS n 1 207 THR n 1 208 ASP n 1 209 TRP n 1 210 CYS n 1 211 ARG n 1 212 CYS n 1 213 SER n 1 214 CYS n 1 215 LEU n 1 216 PRO n 1 217 ASP n 1 218 PRO n 1 219 ILE n 1 220 THR n 1 221 ALA n 1 222 TYR n 1 223 ASP n 1 224 PRO n 1 225 ARG n 1 226 SER n 1 227 CYS n 1 228 SER n 1 229 GLN n 1 230 LYS n 1 231 LYS n 1 232 SER n 1 233 LEU n 1 234 VAL n 1 235 GLY n 1 236 VAL n 1 237 GLY n 1 238 GLU n 1 239 HIS n 1 240 CYS n 1 241 ALA n 1 242 GLY n 1 243 PHE n 1 244 GLY n 1 245 VAL n 1 246 ASP n 1 247 GLU n 1 248 GLU n 1 249 LYS n 1 250 CYS n 1 251 GLY n 1 252 VAL n 1 253 LEU n 1 254 ASP n 1 255 GLY n 1 256 SER n 1 257 TYR n 1 258 ASN n 1 259 VAL n 1 260 SER n 1 261 CYS n 1 262 LEU n 1 263 CYS n 1 264 SER n 1 265 THR n 1 266 ASP n 1 267 ALA n 1 268 PHE n 1 269 LEU n 1 270 GLY n 1 271 TRP n 1 272 SER n 1 273 TYR n 1 274 ASP n 1 275 THR n 1 276 CYS n 1 277 VAL n 1 278 SER n 1 279 ASN n 1 280 ASN n 1 281 ARG n 1 282 CYS n 1 283 ASN n 1 284 ILE n 1 285 PHE n 1 286 SER n 1 287 ASN n 1 288 PHE n 1 289 ILE n 1 290 LEU n 1 291 ASN n 1 292 GLY n 1 293 ILE n 1 294 ASN n 1 295 SER n 1 296 GLY n 1 297 THR n 1 298 THR n 1 299 CYS n 1 300 SER n 1 301 ASN n 1 302 ASP n 1 303 LEU n 1 304 LEU n 1 305 GLN n 1 306 PRO n 1 307 ASN n 1 308 THR n 1 309 GLU n 1 310 VAL n 1 311 PHE n 1 312 THR n 1 313 ASP n 1 314 VAL n 1 315 CYS n 1 316 VAL n 1 317 ASP n 1 318 TYR n 1 319 ASP n 1 320 LEU n 1 321 TYR n 1 322 GLY n 1 323 ILE n 1 324 THR n 1 325 GLY n 1 326 GLN n 1 327 GLY n 1 328 ILE n 1 329 PHE n 1 330 LYS n 1 331 GLU n 1 332 VAL n 1 333 SER n 1 334 ALA n 1 335 VAL n 1 336 TYR n 1 337 TYR n 1 338 ASN n 1 339 SER n 1 340 TRP n 1 341 GLN n 1 342 ASN n 1 343 LEU n 1 344 LEU n 1 345 TYR n 1 346 ASP n 1 347 SER n 1 348 ASN n 1 349 GLY n 1 350 ASN n 1 351 ILE n 1 352 ILE n 1 353 GLY n 1 354 PHE n 1 355 LYS n 1 356 ASP n 1 357 PHE n 1 358 VAL n 1 359 THR n 1 360 ASN n 1 361 LYS n 1 362 THR n 1 363 TYR n 1 364 ASN n 1 365 ILE n 1 366 PHE n 1 367 PRO n 1 368 CYS n 1 369 TYR n 1 370 ALA n 1 371 GLY n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 371 _entity_src_gen.gene_src_common_name HCoV-HKU1 _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'S, 3' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain 'isolate N1' _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Human coronavirus HKU1 (isolate N1)' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 443239 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Trichoplusia ni' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7111 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code SPIKE_CVHN1 _struct_ref.pdbx_db_accession Q5MQD0 _struct_ref.pdbx_db_isoform ? _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;SGFTVKPVATVHRRIPDLPDCDIDKWLNNFNVPSPLNWERKIFSNCNFNLSTLLRLVHTDSFSCNNFDESKIYGSCFKSI VLDKFAIPNSRRSDLQLGSSGFLQSSNYKIDTTSSSCQLYYSLPAINVTINNYNPSSWNRRYGFNNFNLSSHSVVYSRYC FSVNNTFCPCAKPSFASSCKSHKPPSASCPIGTNYRSCESTTVLDHTDWCRCSCLPDPITAYDPRSCSQKKSLVGVGEHC AGFGVDEEKCGVLDGSYNVSCLCSTDAFLGWSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDVCVDYDL YGITGQGIFKEVSAVYYNSWQNLLYDSNGNIIGFKDFVTNKTYNIFPCYAG ; _struct_ref.pdbx_align_begin 307 # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 5GNB _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 371 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q5MQD0 _struct_ref_seq.db_align_beg 307 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 677 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 307 _struct_ref_seq.pdbx_auth_seq_align_end 677 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5GNB _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 3.04 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 60 _exptl_crystal.description 'THE ENTRY CONTAINS FRIEDEL PAIRS IN F_PLUS/MINUS COLUMNS.' _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 8.5 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 291 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '0.1M Tris, 24%PEG4000, 0.2M MgCl2, 4% v/v Pentaerythritol ethoxylate (3/4 EO/OH)' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector PIXEL _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'DECTRIS PILATUS 2M-F' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2015-05-09 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 2.08 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'SLS BEAMLINE X06DA' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 2.08 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline X06DA _diffrn_source.pdbx_synchrotron_site SLS # _reflns.B_iso_Wilson_estimate 31.062 _reflns.entry_id 5GNB _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.3 _reflns.d_resolution_low 49.2 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 43316 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I -3.0 _reflns.percent_possible_obs 99.5 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 89.76 _reflns.pdbx_Rmerge_I_obs 0.23 _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 28.04 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half 0.999 _reflns.pdbx_R_split ? # _reflns_shell.d_res_high 2.30 _reflns_shell.d_res_low 2.36 _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs 3.37 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all 93.9 _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs 1.28 _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy 30.92 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half 0.894 _reflns_shell.pdbx_R_split ? # _refine.aniso_B[1][1] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][2] ? _refine.aniso_B[2][3] ? _refine.aniso_B[3][3] ? _refine.B_iso_max ? _refine.B_iso_mean 30.16 _refine.B_iso_min ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.details 'SF FILE CONTAINS FRIEDEL PAIRS UNDER I/F_MINUS AND I/F_PLUS COLUMNS.' _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 5GNB _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 2.3 _refine.ls_d_res_low 49.2 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 43282 _refine.ls_number_reflns_R_free 2155 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 99.43 _refine.ls_percent_reflns_R_free 4.98 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.1751 _refine.ls_R_factor_R_free 0.2192 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.1728 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details ? _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.93 _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_method_to_determine_struct SAD _refine.pdbx_starting_model ? _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_R_Free_selection_details Random _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error 23.97 _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B ? _refine.overall_SU_ML 0.26 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 2853 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 56 _refine_hist.number_atoms_solvent 234 _refine_hist.number_atoms_total 3143 _refine_hist.d_res_high 2.3 _refine_hist.d_res_low 49.2 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? 0.008 ? 3070 ? f_bond_d ? ? 'X-RAY DIFFRACTION' ? 0.854 ? 4213 ? f_angle_d ? ? 'X-RAY DIFFRACTION' ? 9.968 ? 1859 ? f_dihedral_angle_d ? ? 'X-RAY DIFFRACTION' ? 0.051 ? 468 ? f_chiral_restr ? ? 'X-RAY DIFFRACTION' ? 0.005 ? 546 ? f_plane_restr ? ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.R_factor_R_work _refine_ls_shell.redundancy_reflns_all _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.wR_factor_all _refine_ls_shell.wR_factor_obs _refine_ls_shell.wR_factor_R_free _refine_ls_shell.wR_factor_R_work _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.pdbx_phase_error _refine_ls_shell.pdbx_fsc_work _refine_ls_shell.pdbx_fsc_free 'X-RAY DIFFRACTION' 2.2980 2.3515 . . 137 2595 93.00 . . . 0.3032 . 0.2349 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.3515 2.4103 . . 140 2720 99.00 . . . 0.2566 . 0.2176 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.4103 2.4754 . . 145 2765 100.00 . . . 0.2384 . 0.2056 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.4754 2.5483 . . 141 2762 100.00 . . . 0.2889 . 0.1864 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.5483 2.6305 . . 140 2734 100.00 . . . 0.2993 . 0.1831 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.6305 2.7245 . . 148 2760 100.00 . . . 0.2113 . 0.1706 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.7245 2.8336 . . 147 2745 100.00 . . . 0.2223 . 0.1732 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.8336 2.9625 . . 144 2731 100.00 . . . 0.2372 . 0.1848 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.9625 3.1187 . . 144 2764 100.00 . . . 0.2384 . 0.1914 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.1187 3.3141 . . 143 2762 100.00 . . . 0.2323 . 0.1747 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.3141 3.5699 . . 147 2755 100.00 . . . 0.1869 . 0.1637 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.5699 3.9290 . . 148 2774 100.00 . . . 0.2077 . 0.1545 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.9290 4.4972 . . 142 2741 100.00 . . . 0.2086 . 0.1340 . . . . . . . . . . 'X-RAY DIFFRACTION' 4.4972 5.6647 . . 143 2769 100.00 . . . 0.1463 . 0.1508 . . . . . . . . . . 'X-RAY DIFFRACTION' 5.6647 49.2067 . . 146 2750 100.00 . . . 0.2302 . 0.1947 . . . . . . . . . . # _struct.entry_id 5GNB _struct.title ;Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 2.3 angstrom, native-SAD phasing) ; _struct.pdbx_descriptor 'Spike glycoprotein' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag N # _struct_keywords.entry_id 5GNB _struct_keywords.text 'Coronavirus spike protein, S1-CTD, receptor binding domain, receptor binding motif, virus entry, HKU1, VIRAL PROTEIN' _struct_keywords.pdbx_keywords 'VIRAL PROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 3 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 ASP A 22 ? ASN A 28 ? ASP A 328 ASN A 334 1 ? 7 HELX_P HELX_P2 AA2 PRO A 35 ? TRP A 38 ? PRO A 341 TRP A 344 5 ? 4 HELX_P HELX_P3 AA3 ASN A 49 ? VAL A 57 ? ASN A 355 VAL A 363 1 ? 9 HELX_P HELX_P4 AA4 ASP A 68 ? ILE A 72 ? ASP A 374 ILE A 378 5 ? 5 HELX_P HELX_P5 AA5 PRO A 88 ? GLN A 96 ? PRO A 394 GLN A 402 5 ? 9 HELX_P HELX_P6 AA6 GLY A 101 ? ASN A 107 ? GLY A 407 ASN A 413 1 ? 7 HELX_P HELX_P7 AA7 ILE A 126 ? VAL A 128 ? ILE A 432 VAL A 434 5 ? 3 HELX_P HELX_P8 AA8 SER A 136 ? TYR A 142 ? SER A 442 TYR A 448 1 ? 7 HELX_P HELX_P9 AA9 LYS A 172 ? SER A 177 ? LYS A 478 SER A 483 1 ? 6 HELX_P HELX_P10 AB1 ASP A 223 ? CYS A 227 ? ASP A 529 CYS A 533 5 ? 5 HELX_P HELX_P11 AB2 ASP A 246 ? CYS A 250 ? ASP A 552 CYS A 556 5 ? 5 HELX_P HELX_P12 AB3 SER A 264 ? PHE A 268 ? SER A 570 PHE A 574 5 ? 5 HELX_P HELX_P13 AB4 SER A 333 ? TYR A 337 ? SER A 639 TYR A 643 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 21 SG ? ? ? 1_555 A CYS 46 SG ? ? A CYS 327 A CYS 352 1_555 ? ? ? ? ? ? ? 2.064 ? disulf2 disulf ? ? A CYS 64 SG ? ? ? 1_555 A CYS 117 SG A ? A CYS 370 A CYS 423 1_555 ? ? ? ? ? ? ? 2.050 ? disulf3 disulf ? ? A CYS 76 SG ? ? ? 1_555 A CYS 299 SG A ? A CYS 382 A CYS 605 1_555 ? ? ? ? ? ? ? 2.048 ? disulf4 disulf ? ? A CYS 160 SG A ? ? 1_555 A CYS 240 SG ? ? A CYS 466 A CYS 546 1_555 ? ? ? ? ? ? ? 2.054 ? disulf5 disulf ? ? A CYS 168 SG ? ? ? 1_555 A CYS 189 SG ? ? A CYS 474 A CYS 495 1_555 ? ? ? ? ? ? ? 2.051 ? disulf6 disulf ? ? A CYS 170 SG ? ? ? 1_555 A CYS 261 SG ? ? A CYS 476 A CYS 567 1_555 ? ? ? ? ? ? ? 2.016 ? disulf7 disulf ? ? A CYS 179 SG ? ? ? 1_555 A CYS 210 SG ? ? A CYS 485 A CYS 516 1_555 ? ? ? ? ? ? ? 2.025 ? disulf8 disulf ? ? A CYS 198 SG ? ? ? 1_555 A CYS 212 SG ? ? A CYS 504 A CYS 518 1_555 ? ? ? ? ? ? ? 2.056 ? disulf9 disulf ? ? A CYS 214 SG A ? ? 1_555 A CYS 227 SG ? ? A CYS 520 A CYS 533 1_555 ? ? ? ? ? ? ? 2.055 ? disulf10 disulf ? ? A CYS 250 SG ? ? ? 1_555 A CYS 263 SG ? ? A CYS 556 A CYS 569 1_555 ? ? ? ? ? ? ? 2.071 ? disulf11 disulf ? ? A CYS 276 SG ? ? ? 1_555 A CYS 282 SG B ? A CYS 582 A CYS 588 1_555 ? ? ? ? ? ? ? 2.068 ? disulf12 disulf ? ? A CYS 315 SG ? ? ? 1_555 A CYS 368 SG ? ? A CYS 621 A CYS 674 1_555 ? ? ? ? ? ? ? 2.037 ? covale1 covale one ? A ASN 49 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 355 A NAG 704 1_555 ? ? ? ? ? ? ? 1.440 ? covale2 covale one ? A ASN 127 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 433 A NAG 701 1_555 ? ? ? ? ? ? ? 1.452 ? covale3 covale one ? A ASN 148 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 454 A NAG 703 1_555 ? ? ? ? ? ? ? 1.451 ? covale4 covale one ? A ASN 164 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 470 A NAG 702 1_555 ? ? ? ? ? ? ? 1.455 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # _struct_mon_prot_cis.pdbx_id 1 _struct_mon_prot_cis.label_comp_id LEU _struct_mon_prot_cis.label_seq_id 215 _struct_mon_prot_cis.label_asym_id A _struct_mon_prot_cis.label_alt_id . _struct_mon_prot_cis.pdbx_PDB_ins_code ? _struct_mon_prot_cis.auth_comp_id LEU _struct_mon_prot_cis.auth_seq_id 521 _struct_mon_prot_cis.auth_asym_id A _struct_mon_prot_cis.pdbx_label_comp_id_2 PRO _struct_mon_prot_cis.pdbx_label_seq_id_2 216 _struct_mon_prot_cis.pdbx_label_asym_id_2 A _struct_mon_prot_cis.pdbx_PDB_ins_code_2 ? _struct_mon_prot_cis.pdbx_auth_comp_id_2 PRO _struct_mon_prot_cis.pdbx_auth_seq_id_2 522 _struct_mon_prot_cis.pdbx_auth_asym_id_2 A _struct_mon_prot_cis.pdbx_PDB_model_num 1 _struct_mon_prot_cis.pdbx_omega_angle -3.90 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 6 ? AA2 ? 2 ? AA3 ? 5 ? AA4 ? 4 ? AA5 ? 3 ? AA6 ? 2 ? AA7 ? 2 ? AA8 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? parallel AA1 2 3 ? anti-parallel AA1 3 4 ? anti-parallel AA1 4 5 ? anti-parallel AA1 5 6 ? anti-parallel AA2 1 2 ? parallel AA3 1 2 ? anti-parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA3 4 5 ? anti-parallel AA4 1 2 ? anti-parallel AA4 2 3 ? anti-parallel AA4 3 4 ? anti-parallel AA5 1 2 ? parallel AA5 2 3 ? anti-parallel AA6 1 2 ? anti-parallel AA7 1 2 ? anti-parallel AA8 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 VAL A 11 ? ARG A 13 ? VAL A 317 ARG A 319 AA1 2 CYS A 315 ? LEU A 320 ? CYS A 621 LEU A 626 AA1 3 ILE A 323 ? VAL A 332 ? ILE A 629 VAL A 638 AA1 4 THR A 362 ? PHE A 366 ? THR A 668 PHE A 672 AA1 5 ILE A 351 ? LYS A 355 ? ILE A 657 LYS A 661 AA1 6 LEU A 343 ? TYR A 345 ? LEU A 649 TYR A 651 AA2 1 ASN A 31 ? PRO A 33 ? ASN A 337 PRO A 339 AA2 2 THR A 129 ? ASN A 131 ? THR A 435 ASN A 437 AA3 1 GLU A 39 ? PHE A 43 ? GLU A 345 PHE A 349 AA3 2 SER A 79 ? ALA A 86 ? SER A 385 ALA A 392 AA3 3 ARG A 281 ? ASN A 291 ? ARG A 587 ASN A 597 AA3 4 SER A 116 ? PRO A 124 ? SER A 422 PRO A 430 AA3 5 HIS A 58 ? ASN A 65 ? HIS A 364 ASN A 371 AA4 1 GLU A 39 ? PHE A 43 ? GLU A 345 PHE A 349 AA4 2 SER A 79 ? ALA A 86 ? SER A 385 ALA A 392 AA4 3 ARG A 281 ? ASN A 291 ? ARG A 587 ASN A 597 AA4 4 VAL A 277 ? SER A 278 ? VAL A 583 SER A 584 AA5 1 CYS A 46 ? PHE A 48 ? CYS A 352 PHE A 354 AA5 2 THR A 298 ? SER A 300 ? THR A 604 SER A 606 AA5 3 CYS A 76 ? PHE A 77 ? CYS A 382 PHE A 383 AA6 1 SER A 153 ? SER A 157 ? SER A 459 SER A 463 AA6 2 TRP A 271 ? THR A 275 ? TRP A 577 THR A 581 AA7 1 PHE A 161 ? SER A 162 ? PHE A 467 SER A 468 AA7 2 LYS A 230 ? LYS A 231 ? LYS A 536 LYS A 537 AA8 1 CYS A 198 ? VAL A 203 ? CYS A 504 VAL A 509 AA8 2 HIS A 206 ? CYS A 212 ? HIS A 512 CYS A 518 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N VAL A 11 ? N VAL A 317 O ASP A 319 ? O ASP A 625 AA1 2 3 N TYR A 318 ? N TYR A 624 O GLY A 325 ? O GLY A 631 AA1 3 4 N ILE A 328 ? N ILE A 634 O PHE A 366 ? O PHE A 672 AA1 4 5 O ILE A 365 ? O ILE A 671 N ILE A 352 ? N ILE A 658 AA1 5 6 O ILE A 352 ? O ILE A 658 N LEU A 344 ? N LEU A 650 AA2 1 2 N VAL A 32 ? N VAL A 338 O ASN A 131 ? O ASN A 437 AA3 1 2 N PHE A 43 ? N PHE A 349 O ILE A 80 ? O ILE A 386 AA3 2 3 N PHE A 85 ? N PHE A 391 O PHE A 285 ? O PHE A 591 AA3 3 4 O SER A 286 ? O SER A 592 N LEU A 119 ? N LEU A 425 AA3 4 5 O SER A 116 ? O SER A 422 N ASN A 65 ? N ASN A 371 AA4 1 2 N PHE A 43 ? N PHE A 349 O ILE A 80 ? O ILE A 386 AA4 2 3 N PHE A 85 ? N PHE A 391 O PHE A 285 ? O PHE A 591 AA4 3 4 O ARG A 281 ? O ARG A 587 N SER A 278 ? N SER A 584 AA5 1 2 N PHE A 48 ? N PHE A 354 O CYS A 299 ? O CYS A 605 AA5 2 3 O THR A 298 ? O THR A 604 N PHE A 77 ? N PHE A 383 AA6 1 2 N TYR A 156 ? N TYR A 462 O SER A 272 ? O SER A 578 AA7 1 2 N SER A 162 ? N SER A 468 O LYS A 230 ? O LYS A 536 AA8 1 2 N THR A 201 ? N THR A 507 O TRP A 209 ? O TRP A 515 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A NAG 704 ? 4 'binding site for Mono-Saccharide NAG A 704 bound to ASN A 355' AC2 Software A NAG 701 ? 4 'binding site for Mono-Saccharide NAG A 701 bound to ASN A 433' AC3 Software A NAG 703 ? 1 'binding site for Mono-Saccharide NAG A 703 bound to ASN A 454' AC4 Software A NAG 702 ? 5 'binding site for Mono-Saccharide NAG A 702 bound to ASN A 470' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 ASN A 49 ? ASN A 355 . ? 1_555 ? 2 AC1 4 THR A 52 ? THR A 358 . ? 1_555 ? 3 AC1 4 ASN A 301 ? ASN A 607 . ? 1_555 ? 4 AC1 4 HOH F . ? HOH A 917 . ? 1_555 ? 5 AC2 4 PHE A 30 ? PHE A 336 . ? 1_555 ? 6 AC2 4 ASN A 127 ? ASN A 433 . ? 1_555 ? 7 AC2 4 HOH F . ? HOH A 814 . ? 1_555 ? 8 AC2 4 HOH F . ? HOH A 886 . ? 1_555 ? 9 AC3 1 ASN A 148 ? ASN A 454 . ? 1_555 ? 10 AC4 5 ASN A 164 ? ASN A 470 . ? 1_555 ? 11 AC4 5 ASN A 165 ? ASN A 471 . ? 1_555 ? 12 AC4 5 THR A 166 ? THR A 472 . ? 1_555 ? 13 AC4 5 HOH F . ? HOH A 802 . ? 1_555 ? 14 AC4 5 HOH F . ? HOH A 807 . ? 1_555 ? # _atom_sites.entry_id 5GNB _atom_sites.fract_transf_matrix[1][1] 0.011531 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.005435 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.015833 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C H N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . VAL A 1 5 ? 0.598 218.171 -7.612 1.00 73.83 ? 311 VAL A N 1 ATOM 2 C CA . VAL A 1 5 ? 1.971 218.643 -7.473 1.00 83.70 ? 311 VAL A CA 1 ATOM 3 C C . VAL A 1 5 ? 2.045 220.138 -7.778 1.00 89.05 ? 311 VAL A C 1 ATOM 4 O O . VAL A 1 5 ? 1.483 220.609 -8.773 1.00 86.44 ? 311 VAL A O 1 ATOM 5 C CB . VAL A 1 5 ? 2.931 217.846 -8.392 1.00 77.63 ? 311 VAL A CB 1 ATOM 6 C CG1 . VAL A 1 5 ? 4.338 218.434 -8.359 1.00 68.28 ? 311 VAL A CG1 1 ATOM 7 C CG2 . VAL A 1 5 ? 2.967 216.378 -7.975 1.00 74.26 ? 311 VAL A CG2 1 ATOM 8 H HA . VAL A 1 5 ? 2.258 218.511 -6.556 1.00 100.43 ? 311 VAL A HA 1 ATOM 9 H HB . VAL A 1 5 ? 2.607 217.892 -9.305 1.00 93.15 ? 311 VAL A HB 1 ATOM 10 H HG11 . VAL A 1 5 ? 4.911 217.914 -8.943 1.00 81.93 ? 311 VAL A HG11 1 ATOM 11 H HG12 . VAL A 1 5 ? 4.302 219.354 -8.664 1.00 81.93 ? 311 VAL A HG12 1 ATOM 12 H HG13 . VAL A 1 5 ? 4.672 218.400 -7.449 1.00 81.93 ? 311 VAL A HG13 1 ATOM 13 H HG21 . VAL A 1 5 ? 3.572 215.898 -8.562 1.00 89.11 ? 311 VAL A HG21 1 ATOM 14 H HG22 . VAL A 1 5 ? 3.277 216.318 -7.058 1.00 89.11 ? 311 VAL A HG22 1 ATOM 15 H HG23 . VAL A 1 5 ? 2.073 216.008 -8.047 1.00 89.11 ? 311 VAL A HG23 1 ATOM 16 N N . LYS A 1 6 ? 2.744 220.875 -6.918 1.00 78.90 ? 312 LYS A N 1 ATOM 17 C CA . LYS A 1 6 ? 2.970 222.295 -7.159 1.00 76.60 ? 312 LYS A CA 1 ATOM 18 C C . LYS A 1 6 ? 3.742 222.479 -8.465 1.00 62.53 ? 312 LYS A C 1 ATOM 19 O O . LYS A 1 6 ? 4.743 221.786 -8.690 1.00 54.05 ? 312 LYS A O 1 ATOM 20 C CB . LYS A 1 6 ? 3.749 222.918 -5.999 1.00 78.24 ? 312 LYS A CB 1 ATOM 21 C CG . LYS A 1 6 ? 3.109 222.702 -4.628 1.00 98.13 ? 312 LYS A CG 1 ATOM 22 C CD . LYS A 1 6 ? 3.958 223.279 -3.488 1.00 106.99 ? 312 LYS A CD 1 ATOM 23 C CE . LYS A 1 6 ? 5.275 222.514 -3.286 1.00 78.27 ? 312 LYS A CE 1 ATOM 24 N NZ . LYS A 1 6 ? 5.073 221.067 -3.041 1.00 49.83 ? 312 LYS A NZ 1 ATOM 25 H H . LYS A 1 6 ? 3.095 220.578 -6.192 1.00 94.68 ? 312 LYS A H 1 ATOM 26 H HA . LYS A 1 6 ? 2.117 222.751 -7.238 1.00 91.92 ? 312 LYS A HA 1 ATOM 27 H HB2 . LYS A 1 6 ? 4.637 222.528 -5.975 1.00 93.88 ? 312 LYS A HB2 1 ATOM 28 H HB3 . LYS A 1 6 ? 3.816 223.875 -6.146 1.00 93.88 ? 312 LYS A HB3 1 ATOM 29 H HG2 . LYS A 1 6 ? 2.244 223.140 -4.609 1.00 117.76 ? 312 LYS A HG2 1 ATOM 30 H HG3 . LYS A 1 6 ? 3.004 221.750 -4.473 1.00 117.76 ? 312 LYS A HG3 1 ATOM 31 H HD2 . LYS A 1 6 ? 4.175 224.202 -3.691 1.00 128.39 ? 312 LYS A HD2 1 ATOM 32 H HD3 . LYS A 1 6 ? 3.453 223.230 -2.661 1.00 128.39 ? 312 LYS A HD3 1 ATOM 33 H HE2 . LYS A 1 6 ? 5.820 222.608 -4.084 1.00 93.93 ? 312 LYS A HE2 1 ATOM 34 H HE3 . LYS A 1 6 ? 5.742 222.885 -2.521 1.00 93.93 ? 312 LYS A HE3 1 ATOM 35 H HZ1 . LYS A 1 6 ? 5.860 220.665 -2.930 1.00 59.79 ? 312 LYS A HZ1 1 ATOM 36 H HZ2 . LYS A 1 6 ? 4.582 220.949 -2.308 1.00 59.79 ? 312 LYS A HZ2 1 ATOM 37 H HZ3 . LYS A 1 6 ? 4.654 220.697 -3.733 1.00 59.79 ? 312 LYS A HZ3 1 ATOM 38 N N . PRO A 1 7 ? 3.328 223.387 -9.340 1.00 63.45 ? 313 PRO A N 1 ATOM 39 C CA . PRO A 1 7 ? 4.035 223.542 -10.614 1.00 55.47 ? 313 PRO A CA 1 ATOM 40 C C . PRO A 1 7 ? 5.319 224.350 -10.474 1.00 47.03 ? 313 PRO A C 1 ATOM 41 O O . PRO A 1 7 ? 5.455 225.225 -9.615 1.00 39.43 ? 313 PRO A O 1 ATOM 42 C CB . PRO A 1 7 ? 3.012 224.271 -11.492 1.00 53.92 ? 313 PRO A CB 1 ATOM 43 C CG . PRO A 1 7 ? 2.238 225.102 -10.512 1.00 57.51 ? 313 PRO A CG 1 ATOM 44 C CD . PRO A 1 7 ? 2.159 224.282 -9.247 1.00 60.71 ? 313 PRO A CD 1 ATOM 45 H HA . PRO A 1 7 ? 4.236 222.675 -11.001 1.00 66.57 ? 313 PRO A HA 1 ATOM 46 H HB2 . PRO A 1 7 ? 3.469 224.831 -12.139 1.00 64.71 ? 313 PRO A HB2 1 ATOM 47 H HB3 . PRO A 1 7 ? 2.435 223.627 -11.933 1.00 64.71 ? 313 PRO A HB3 1 ATOM 48 H HG2 . PRO A 1 7 ? 2.709 225.935 -10.350 1.00 69.02 ? 313 PRO A HG2 1 ATOM 49 H HG3 . PRO A 1 7 ? 1.350 225.275 -10.863 1.00 69.02 ? 313 PRO A HG3 1 ATOM 50 H HD2 . PRO A 1 7 ? 2.234 224.855 -8.468 1.00 72.85 ? 313 PRO A HD2 1 ATOM 51 H HD3 . PRO A 1 7 ? 1.338 223.765 -9.231 1.00 72.85 ? 313 PRO A HD3 1 ATOM 52 N N . VAL A 1 8 ? 6.276 224.028 -11.346 1.00 43.43 ? 314 VAL A N 1 ATOM 53 C CA . VAL A 1 8 ? 7.511 224.797 -11.420 1.00 48.14 ? 314 VAL A CA 1 ATOM 54 C C . VAL A 1 8 ? 7.191 226.261 -11.757 1.00 42.85 ? 314 VAL A C 1 ATOM 55 O O . VAL A 1 8 ? 6.248 226.563 -12.498 1.00 35.01 ? 314 VAL A O 1 ATOM 56 C CB . VAL A 1 8 ? 8.454 224.179 -12.468 1.00 45.33 ? 314 VAL A CB 1 ATOM 57 C CG1 . VAL A 1 8 ? 9.782 224.919 -12.509 1.00 47.08 ? 314 VAL A CG1 1 ATOM 58 C CG2 . VAL A 1 8 ? 8.682 222.697 -12.175 1.00 49.10 ? 314 VAL A CG2 1 ATOM 59 H H . VAL A 1 8 ? 6.232 223.373 -11.901 1.00 52.12 ? 314 VAL A H 1 ATOM 60 H HA . VAL A 1 8 ? 7.955 224.773 -10.559 1.00 57.77 ? 314 VAL A HA 1 ATOM 61 H HB . VAL A 1 8 ? 8.043 224.252 -13.344 1.00 54.39 ? 314 VAL A HB 1 ATOM 62 H HG11 . VAL A 1 8 ? 10.352 224.507 -13.177 1.00 56.49 ? 314 VAL A HG11 1 ATOM 63 H HG12 . VAL A 1 8 ? 9.619 225.847 -12.740 1.00 56.49 ? 314 VAL A HG12 1 ATOM 64 H HG13 . VAL A 1 8 ? 10.201 224.863 -11.636 1.00 56.49 ? 314 VAL A HG13 1 ATOM 65 H HG21 . VAL A 1 8 ? 9.278 222.331 -12.848 1.00 58.91 ? 314 VAL A HG21 1 ATOM 66 H HG22 . VAL A 1 8 ? 9.080 222.607 -11.295 1.00 58.91 ? 314 VAL A HG22 1 ATOM 67 H HG23 . VAL A 1 8 ? 7.829 222.236 -12.202 1.00 58.91 ? 314 VAL A HG23 1 ATOM 68 N N . ALA A 1 9 ? 7.981 227.176 -11.200 1.00 39.80 ? 315 ALA A N 1 ATOM 69 C CA . ALA A 1 9 ? 7.726 228.598 -11.391 1.00 44.75 ? 315 ALA A CA 1 ATOM 70 C C . ALA A 1 9 ? 8.002 229.012 -12.833 1.00 41.66 ? 315 ALA A C 1 ATOM 71 O O . ALA A 1 9 ? 8.921 228.511 -13.488 1.00 38.43 ? 315 ALA A O 1 ATOM 72 C CB . ALA A 1 9 ? 8.580 229.430 -10.436 1.00 35.58 ? 315 ALA A CB 1 ATOM 73 H H . ALA A 1 9 ? 8.665 226.999 -10.710 1.00 47.76 ? 315 ALA A H 1 ATOM 74 H HA . ALA A 1 9 ? 6.793 228.782 -11.198 1.00 53.70 ? 315 ALA A HA 1 ATOM 75 H HB1 . ALA A 1 9 ? 8.392 230.370 -10.583 1.00 42.70 ? 315 ALA A HB1 1 ATOM 76 H HB2 . ALA A 1 9 ? 8.360 229.187 -9.523 1.00 42.70 ? 315 ALA A HB2 1 ATOM 77 H HB3 . ALA A 1 9 ? 9.516 229.248 -10.611 1.00 42.70 ? 315 ALA A HB3 1 ATOM 78 N N . THR A 1 10 ? 7.192 229.953 -13.323 1.00 46.55 ? 316 THR A N 1 ATOM 79 C CA . THR A 1 10 ? 7.326 230.400 -14.706 1.00 36.71 ? 316 THR A CA 1 ATOM 80 C C . THR A 1 10 ? 8.723 230.947 -14.974 1.00 31.92 ? 316 THR A C 1 ATOM 81 O O . THR A 1 10 ? 9.296 230.704 -16.038 1.00 39.38 ? 316 THR A O 1 ATOM 82 C CB . THR A 1 10 ? 6.266 231.451 -15.013 1.00 45.52 ? 316 THR A CB 1 ATOM 83 O OG1 . THR A 1 10 ? 4.975 230.972 -14.607 1.00 44.61 ? 316 THR A OG1 1 ATOM 84 C CG2 . THR A 1 10 ? 6.243 231.770 -16.499 1.00 37.29 ? 316 THR A CG2 1 ATOM 85 H H . THR A 1 10 ? 6.566 230.342 -12.880 1.00 55.86 ? 316 THR A H 1 ATOM 86 H HA . THR A 1 10 ? 7.181 229.645 -15.297 1.00 44.05 ? 316 THR A HA 1 ATOM 87 H HB . THR A 1 10 ? 6.472 232.266 -14.529 1.00 54.62 ? 316 THR A HB 1 ATOM 88 H HG1 . THR A 1 10 ? 4.974 230.813 -13.782 1.00 53.53 ? 316 THR A HG1 1 ATOM 89 H HG21 . THR A 1 10 ? 5.565 232.439 -16.684 1.00 44.75 ? 316 THR A HG21 1 ATOM 90 H HG22 . THR A 1 10 ? 7.107 232.110 -16.779 1.00 44.75 ? 316 THR A HG22 1 ATOM 91 H HG23 . THR A 1 10 ? 6.040 230.968 -17.007 1.00 44.75 ? 316 THR A HG23 1 ATOM 92 N N . VAL A 1 11 ? 9.291 231.683 -14.021 1.00 37.58 ? 317 VAL A N 1 ATOM 93 C CA . VAL A 1 11 ? 10.674 232.141 -14.100 1.00 37.28 ? 317 VAL A CA 1 ATOM 94 C C . VAL A 1 11 ? 11.436 231.505 -12.949 1.00 31.93 ? 317 VAL A C 1 ATOM 95 O O . VAL A 1 11 ? 11.210 231.848 -11.779 1.00 29.94 ? 317 VAL A O 1 ATOM 96 C CB . VAL A 1 11 ? 10.792 233.672 -14.052 1.00 38.10 ? 317 VAL A CB 1 ATOM 97 C CG1 . VAL A 1 11 ? 12.261 234.084 -14.035 1.00 33.05 ? 317 VAL A CG1 1 ATOM 98 C CG2 . VAL A 1 11 ? 10.102 234.286 -15.246 1.00 37.99 ? 317 VAL A CG2 1 ATOM 99 H H . VAL A 1 11 ? 8.886 231.933 -13.305 1.00 45.09 ? 317 VAL A H 1 ATOM 100 H HA . VAL A 1 11 ? 11.067 231.832 -14.931 1.00 44.74 ? 317 VAL A HA 1 ATOM 101 H HB . VAL A 1 11 ? 10.369 234.005 -13.246 1.00 45.72 ? 317 VAL A HB 1 ATOM 102 H HG11 . VAL A 1 11 ? 12.316 235.052 -14.005 1.00 39.66 ? 317 VAL A HG11 1 ATOM 103 H HG12 . VAL A 1 11 ? 12.686 233.704 -13.251 1.00 39.66 ? 317 VAL A HG12 1 ATOM 104 H HG13 . VAL A 1 11 ? 12.691 233.753 -14.839 1.00 39.66 ? 317 VAL A HG13 1 ATOM 105 H HG21 . VAL A 1 11 ? 10.188 235.251 -15.197 1.00 45.59 ? 317 VAL A HG21 1 ATOM 106 H HG22 . VAL A 1 11 ? 10.520 233.957 -16.056 1.00 45.59 ? 317 VAL A HG22 1 ATOM 107 H HG23 . VAL A 1 11 ? 9.165 234.036 -15.231 1.00 45.59 ? 317 VAL A HG23 1 ATOM 108 N N . HIS A 1 12 ? 12.366 230.614 -13.282 1.00 28.60 ? 318 HIS A N 1 ATOM 109 C CA . HIS A 1 12 ? 13.107 229.846 -12.295 1.00 28.68 ? 318 HIS A CA 1 ATOM 110 C C . HIS A 1 12 ? 14.596 229.972 -12.559 1.00 26.13 ? 318 HIS A C 1 ATOM 111 O O . HIS A 1 12 ? 15.041 229.816 -13.699 1.00 31.93 ? 318 HIS A O 1 ATOM 112 C CB . HIS A 1 12 ? 12.709 228.358 -12.327 1.00 32.38 ? 318 HIS A CB 1 ATOM 113 C CG . HIS A 1 12 ? 13.369 227.556 -11.254 1.00 30.59 ? 318 HIS A CG 1 ATOM 114 N ND1 . HIS A 1 12 ? 14.661 227.093 -11.367 1.00 32.08 ? 318 HIS A ND1 1 ATOM 115 C CD2 . HIS A 1 12 ? 12.943 227.192 -10.021 1.00 28.97 ? 318 HIS A CD2 1 ATOM 116 C CE1 . HIS A 1 12 ? 14.994 226.457 -10.257 1.00 34.19 ? 318 HIS A CE1 1 ATOM 117 N NE2 . HIS A 1 12 ? 13.971 226.504 -9.425 1.00 25.97 ? 318 HIS A NE2 1 ATOM 118 H H . HIS A 1 12 ? 12.588 230.435 -14.093 1.00 34.32 ? 318 HIS A H 1 ATOM 119 H HA . HIS A 1 12 ? 12.922 230.194 -11.409 1.00 34.42 ? 318 HIS A HA 1 ATOM 120 H HB2 . HIS A 1 12 ? 11.749 228.286 -12.207 1.00 38.86 ? 318 HIS A HB2 1 ATOM 121 H HB3 . HIS A 1 12 ? 12.966 227.981 -13.183 1.00 38.86 ? 318 HIS A HB3 1 ATOM 122 H HD1 . HIS A 1 12 ? 15.169 227.197 -12.053 1.00 38.49 ? 318 HIS A HD1 1 ATOM 123 H HD2 . HIS A 1 12 ? 12.109 227.370 -9.650 1.00 34.76 ? 318 HIS A HD2 1 ATOM 124 H HE1 . HIS A 1 12 ? 15.810 226.042 -10.093 1.00 41.03 ? 318 HIS A HE1 1 ATOM 125 N N . ARG A 1 13 ? 15.364 230.244 -11.509 1.00 26.26 ? 319 ARG A N 1 ATOM 126 C CA A ARG A 1 13 ? 16.818 230.266 -11.601 0.04 31.59 ? 319 ARG A CA 1 ATOM 127 C CA B ARG A 1 13 ? 16.818 230.264 -11.600 0.96 31.65 ? 319 ARG A CA 1 ATOM 128 C C . ARG A 1 13 ? 17.399 229.583 -10.373 1.00 32.23 ? 319 ARG A C 1 ATOM 129 O O . ARG A 1 13 ? 16.994 229.876 -9.241 1.00 27.37 ? 319 ARG A O 1 ATOM 130 C CB A ARG A 1 13 ? 17.355 231.699 -11.720 0.04 33.79 ? 319 ARG A CB 1 ATOM 131 C CB B ARG A 1 13 ? 17.360 231.698 -11.711 0.96 33.79 ? 319 ARG A CB 1 ATOM 132 C CG A ARG A 1 13 ? 16.783 232.498 -12.887 0.04 32.02 ? 319 ARG A CG 1 ATOM 133 C CG B ARG A 1 13 ? 17.026 232.408 -13.005 0.96 30.67 ? 319 ARG A CG 1 ATOM 134 C CD A ARG A 1 13 ? 17.300 232.006 -14.233 0.04 36.14 ? 319 ARG A CD 1 ATOM 135 C CD B ARG A 1 13 ? 17.715 231.743 -14.194 0.96 36.74 ? 319 ARG A CD 1 ATOM 136 N NE A ARG A 1 13 ? 16.630 232.671 -15.349 0.04 37.57 ? 319 ARG A NE 1 ATOM 137 N NE B ARG A 1 13 ? 17.556 232.490 -15.446 0.96 40.26 ? 319 ARG A NE 1 ATOM 138 C CZ A ARG A 1 13 ? 16.992 232.549 -16.623 0.04 39.86 ? 319 ARG A CZ 1 ATOM 139 C CZ B ARG A 1 13 ? 16.531 232.364 -16.285 0.96 38.76 ? 319 ARG A CZ 1 ATOM 140 N NH1 A ARG A 1 13 ? 18.026 231.790 -16.955 0.04 41.71 ? 319 ARG A NH1 1 ATOM 141 N NH1 B ARG A 1 13 ? 15.535 231.530 -16.020 0.96 38.09 ? 319 ARG A NH1 1 ATOM 142 N NH2 A ARG A 1 13 ? 16.320 233.191 -17.569 0.04 41.59 ? 319 ARG A NH2 1 ATOM 143 N NH2 B ARG A 1 13 ? 16.496 233.086 -17.397 0.96 42.34 ? 319 ARG A NH2 1 ATOM 144 H H . ARG A 1 13 ? 15.062 230.422 -10.723 1.00 31.51 ? 319 ARG A H 1 ATOM 145 H HA A ARG A 1 13 ? 17.097 229.770 -12.387 0.04 37.91 ? 319 ARG A HA 1 ATOM 146 H HA B ARG A 1 13 ? 17.097 229.770 -12.386 0.96 37.97 ? 319 ARG A HA 1 ATOM 147 H HB2 A ARG A 1 13 ? 17.142 232.178 -10.904 0.04 40.54 ? 319 ARG A HB2 1 ATOM 148 H HB2 B ARG A 1 13 ? 16.991 232.224 -10.984 0.96 40.55 ? 319 ARG A HB2 1 ATOM 149 H HB3 A ARG A 1 13 ? 18.317 231.661 -11.834 0.04 40.54 ? 319 ARG A HB3 1 ATOM 150 H HB3 B ARG A 1 13 ? 18.326 231.669 -11.634 0.96 40.55 ? 319 ARG A HB3 1 ATOM 151 H HG2 A ARG A 1 13 ? 15.816 232.413 -12.886 0.04 38.42 ? 319 ARG A HG2 1 ATOM 152 H HG2 B ARG A 1 13 ? 16.067 232.375 -13.151 0.96 36.80 ? 319 ARG A HG2 1 ATOM 153 H HG3 A ARG A 1 13 ? 17.036 233.429 -12.789 0.04 38.42 ? 319 ARG A HG3 1 ATOM 154 H HG3 B ARG A 1 13 ? 17.327 233.328 -12.954 0.96 36.80 ? 319 ARG A HG3 1 ATOM 155 H HD2 A ARG A 1 13 ? 18.250 232.191 -14.296 0.04 43.37 ? 319 ARG A HD2 1 ATOM 156 H HD2 B ARG A 1 13 ? 18.664 231.671 -14.007 0.96 44.09 ? 319 ARG A HD2 1 ATOM 157 H HD3 A ARG A 1 13 ? 17.139 231.053 -14.307 0.04 43.37 ? 319 ARG A HD3 1 ATOM 158 H HD3 B ARG A 1 13 ? 17.336 230.859 -14.323 0.96 44.09 ? 319 ARG A HD3 1 ATOM 159 H HE A ARG A 1 13 ? 15.957 233.175 -15.170 0.04 45.08 ? 319 ARG A HE 1 ATOM 160 H HE B ARG A 1 13 ? 18.173 233.052 -15.654 0.96 48.31 ? 319 ARG A HE 1 ATOM 161 H HH11 A ARG A 1 13 ? 18.466 231.371 -16.346 0.04 50.06 ? 319 ARG A HH11 1 ATOM 162 H HH11 B ARG A 1 13 ? 15.550 231.057 -15.302 0.96 45.70 ? 319 ARG A HH11 1 ATOM 163 H HH12 A ARG A 1 13 ? 18.257 231.715 -17.780 0.04 50.06 ? 319 ARG A HH12 1 ATOM 164 H HH12 B ARG A 1 13 ? 14.876 231.459 -16.568 0.96 45.70 ? 319 ARG A HH12 1 ATOM 165 H HH21 A ARG A 1 13 ? 15.649 233.686 -17.359 0.04 49.91 ? 319 ARG A HH21 1 ATOM 166 H HH21 B ARG A 1 13 ? 17.136 233.632 -17.575 0.96 50.81 ? 319 ARG A HH21 1 ATOM 167 H HH22 A ARG A 1 13 ? 16.556 233.113 -18.392 0.04 49.91 ? 319 ARG A HH22 1 ATOM 168 H HH22 B ARG A 1 13 ? 15.831 233.011 -17.938 0.96 50.81 ? 319 ARG A HH22 1 ATOM 169 N N . ARG A 1 14 ? 18.339 228.676 -10.597 1.00 28.41 ? 320 ARG A N 1 ATOM 170 C CA . ARG A 1 14 ? 18.995 228.005 -9.492 1.00 32.47 ? 320 ARG A CA 1 ATOM 171 C C . ARG A 1 14 ? 20.171 228.820 -8.997 1.00 29.81 ? 320 ARG A C 1 ATOM 172 O O . ARG A 1 14 ? 20.775 229.604 -9.731 1.00 34.49 ? 320 ARG A O 1 ATOM 173 C CB . ARG A 1 14 ? 19.506 226.624 -9.889 1.00 26.28 ? 320 ARG A CB 1 ATOM 174 C CG . ARG A 1 14 ? 18.518 225.786 -10.600 1.00 33.34 ? 320 ARG A CG 1 ATOM 175 C CD . ARG A 1 14 ? 19.017 224.366 -10.705 1.00 39.90 ? 320 ARG A CD 1 ATOM 176 N NE . ARG A 1 14 ? 17.985 223.489 -11.233 1.00 38.16 ? 320 ARG A NE 1 ATOM 177 C CZ . ARG A 1 14 ? 18.193 222.220 -11.544 1.00 36.45 ? 320 ARG A CZ 1 ATOM 178 N NH1 . ARG A 1 14 ? 19.407 221.698 -11.400 1.00 28.85 ? 320 ARG A NH1 1 ATOM 179 N NH2 . ARG A 1 14 ? 17.189 221.484 -11.999 1.00 40.75 ? 320 ARG A NH2 1 ATOM 180 H H . ARG A 1 14 ? 18.613 228.435 -11.376 1.00 34.09 ? 320 ARG A H 1 ATOM 181 H HA . ARG A 1 14 ? 18.366 227.900 -8.761 1.00 38.96 ? 320 ARG A HA 1 ATOM 182 H HB2 . ARG A 1 14 ? 20.273 226.733 -10.472 1.00 31.54 ? 320 ARG A HB2 1 ATOM 183 H HB3 . ARG A 1 14 ? 19.771 226.149 -9.086 1.00 31.54 ? 320 ARG A HB3 1 ATOM 184 H HG2 . ARG A 1 14 ? 17.682 225.784 -10.109 1.00 40.00 ? 320 ARG A HG2 1 ATOM 185 H HG3 . ARG A 1 14 ? 18.385 226.133 -11.497 1.00 40.00 ? 320 ARG A HG3 1 ATOM 186 H HD2 . ARG A 1 14 ? 19.779 224.336 -11.304 1.00 47.89 ? 320 ARG A HD2 1 ATOM 187 H HD3 . ARG A 1 14 ? 19.267 224.048 -9.824 1.00 47.89 ? 320 ARG A HD3 1 ATOM 188 H HE . ARG A 1 14 ? 17.234 223.841 -11.459 1.00 45.79 ? 320 ARG A HE 1 ATOM 189 H HH11 . ARG A 1 14 ? 20.050 222.183 -11.099 1.00 34.62 ? 320 ARG A HH11 1 ATOM 190 H HH12 . ARG A 1 14 ? 19.548 220.875 -11.605 1.00 34.62 ? 320 ARG A HH12 1 ATOM 191 H HH21 . ARG A 1 14 ? 16.409 221.833 -12.094 1.00 48.90 ? 320 ARG A HH21 1 ATOM 192 H HH22 . ARG A 1 14 ? 17.321 220.662 -12.213 1.00 48.90 ? 320 ARG A HH22 1 ATOM 193 N N . ILE A 1 15 ? 20.520 228.581 -7.747 1.00 30.72 ? 321 ILE A N 1 ATOM 194 C CA . ILE A 1 15 ? 21.741 229.159 -7.190 1.00 34.84 ? 321 ILE A CA 1 ATOM 195 C C . ILE A 1 15 ? 22.938 228.509 -7.876 1.00 39.15 ? 321 ILE A C 1 ATOM 196 O O . ILE A 1 15 ? 22.971 227.273 -7.992 1.00 39.15 ? 321 ILE A O 1 ATOM 197 C CB . ILE A 1 15 ? 21.786 228.937 -5.680 1.00 32.10 ? 321 ILE A CB 1 ATOM 198 C CG1 . ILE A 1 15 ? 20.546 229.550 -5.024 1.00 28.80 ? 321 ILE A CG1 1 ATOM 199 C CG2 . ILE A 1 15 ? 23.071 229.510 -5.090 1.00 32.67 ? 321 ILE A CG2 1 ATOM 200 C CD1 . ILE A 1 15 ? 20.515 229.411 -3.525 1.00 22.15 ? 321 ILE A CD1 1 ATOM 201 H H . ILE A 1 15 ? 20.074 228.092 -7.198 1.00 36.87 ? 321 ILE A H 1 ATOM 202 H HA . ILE A 1 15 ? 21.762 230.112 -7.365 1.00 41.81 ? 321 ILE A HA 1 ATOM 203 H HB . ILE A 1 15 ? 21.776 227.981 -5.513 1.00 38.52 ? 321 ILE A HB 1 ATOM 204 H HG12 . ILE A 1 15 ? 20.518 230.497 -5.234 1.00 34.56 ? 321 ILE A HG12 1 ATOM 205 H HG13 . ILE A 1 15 ? 19.757 229.111 -5.378 1.00 34.56 ? 321 ILE A HG13 1 ATOM 206 H HG21 . ILE A 1 15 ? 23.074 229.356 -4.132 1.00 39.21 ? 321 ILE A HG21 1 ATOM 207 H HG22 . ILE A 1 15 ? 23.830 229.067 -5.499 1.00 39.21 ? 321 ILE A HG22 1 ATOM 208 H HG23 . ILE A 1 15 ? 23.104 230.462 -5.273 1.00 39.21 ? 321 ILE A HG23 1 ATOM 209 H HD11 . ILE A 1 15 ? 19.704 229.822 -3.187 1.00 26.58 ? 321 ILE A HD11 1 ATOM 210 H HD12 . ILE A 1 15 ? 20.530 228.469 -3.295 1.00 26.58 ? 321 ILE A HD12 1 ATOM 211 H HD13 . ILE A 1 15 ? 21.292 229.856 -3.151 1.00 26.58 ? 321 ILE A HD13 1 ATOM 212 N N . PRO A 1 16 ? 23.918 229.268 -8.366 1.00 47.40 ? 322 PRO A N 1 ATOM 213 C CA . PRO A 1 16 ? 25.088 228.638 -8.976 1.00 46.09 ? 322 PRO A CA 1 ATOM 214 C C . PRO A 1 16 ? 26.134 228.290 -7.929 1.00 44.80 ? 322 PRO A C 1 ATOM 215 O O . PRO A 1 16 ? 26.197 228.876 -6.848 1.00 51.24 ? 322 PRO A O 1 ATOM 216 C CB . PRO A 1 16 ? 25.607 229.713 -9.943 1.00 51.54 ? 322 PRO A CB 1 ATOM 217 C CG . PRO A 1 16 ? 24.605 230.875 -9.864 1.00 45.88 ? 322 PRO A CG 1 ATOM 218 C CD . PRO A 1 16 ? 23.980 230.736 -8.518 1.00 45.08 ? 322 PRO A CD 1 ATOM 219 H HA . PRO A 1 16 ? 24.836 227.843 -9.471 1.00 55.31 ? 322 PRO A HA 1 ATOM 220 H HB2 . PRO A 1 16 ? 26.489 230.004 -9.661 1.00 61.85 ? 322 PRO A HB2 1 ATOM 221 H HB3 . PRO A 1 16 ? 25.639 229.352 -10.843 1.00 61.85 ? 322 PRO A HB3 1 ATOM 222 H HG2 . PRO A 1 16 ? 25.075 231.720 -9.940 1.00 55.05 ? 322 PRO A HG2 1 ATOM 223 H HG3 . PRO A 1 16 ? 23.941 230.784 -10.564 1.00 55.05 ? 322 PRO A HG3 1 ATOM 224 H HD2 . PRO A 1 16 ? 24.546 231.129 -7.835 1.00 54.09 ? 322 PRO A HD2 1 ATOM 225 H HD3 . PRO A 1 16 ? 23.089 231.120 -8.514 1.00 54.09 ? 322 PRO A HD3 1 ATOM 226 N N . ASP A 1 17 ? 26.949 227.298 -8.270 1.00 46.04 ? 323 ASP A N 1 ATOM 227 C CA . ASP A 1 17 ? 28.102 226.914 -7.456 1.00 50.12 ? 323 ASP A CA 1 ATOM 228 C C . ASP A 1 17 ? 27.698 226.391 -6.075 1.00 38.47 ? 323 ASP A C 1 ATOM 229 O O . ASP A 1 17 ? 28.364 226.655 -5.073 1.00 34.74 ? 323 ASP A O 1 ATOM 230 C CB . ASP A 1 17 ? 29.080 228.080 -7.328 1.00 45.72 ? 323 ASP A CB 1 ATOM 231 C CG . ASP A 1 17 ? 29.802 228.367 -8.620 1.00 60.97 ? 323 ASP A CG 1 ATOM 232 O OD1 . ASP A 1 17 ? 30.055 227.400 -9.371 1.00 67.73 ? 323 ASP A OD1 1 ATOM 233 O OD2 . ASP A 1 17 ? 30.107 229.548 -8.893 1.00 70.51 ? 323 ASP A OD2 1 ATOM 234 H H . ASP A 1 17 ? 26.855 226.823 -8.981 1.00 55.25 ? 323 ASP A H 1 ATOM 235 H HA . ASP A 1 17 ? 28.568 226.195 -7.911 1.00 60.14 ? 323 ASP A HA 1 ATOM 236 H HB2 . ASP A 1 17 ? 28.592 228.878 -7.072 1.00 54.86 ? 323 ASP A HB2 1 ATOM 237 H HB3 . ASP A 1 17 ? 29.744 227.865 -6.654 1.00 54.86 ? 323 ASP A HB3 1 ATOM 238 N N . LEU A 1 18 ? 26.622 225.617 -6.017 1.00 43.81 ? 324 LEU A N 1 ATOM 239 C CA . LEU A 1 18 ? 26.363 224.871 -4.794 1.00 32.69 ? 324 LEU A CA 1 ATOM 240 C C . LEU A 1 18 ? 27.215 223.604 -4.747 1.00 26.68 ? 324 LEU A C 1 ATOM 241 O O . LEU A 1 18 ? 27.552 223.031 -5.787 1.00 29.14 ? 324 LEU A O 1 ATOM 242 C CB . LEU A 1 18 ? 24.892 224.497 -4.697 1.00 28.33 ? 324 LEU A CB 1 ATOM 243 C CG . LEU A 1 18 ? 23.936 225.654 -4.406 1.00 36.50 ? 324 LEU A CG 1 ATOM 244 C CD1 . LEU A 1 18 ? 22.518 225.135 -4.439 1.00 36.29 ? 324 LEU A CD1 1 ATOM 245 C CD2 . LEU A 1 18 ? 24.227 226.343 -3.062 1.00 25.30 ? 324 LEU A CD2 1 ATOM 246 H H . LEU A 1 18 ? 26.046 225.508 -6.646 1.00 52.57 ? 324 LEU A H 1 ATOM 247 H HA . LEU A 1 18 ? 26.589 225.421 -4.028 1.00 39.23 ? 324 LEU A HA 1 ATOM 248 H HB2 . LEU A 1 18 ? 24.620 224.100 -5.540 1.00 33.99 ? 324 LEU A HB2 1 ATOM 249 H HB3 . LEU A 1 18 ? 24.787 223.847 -3.985 1.00 33.99 ? 324 LEU A HB3 1 ATOM 250 H HG . LEU A 1 18 ? 24.026 226.319 -5.107 1.00 43.81 ? 324 LEU A HG 1 ATOM 251 H HD11 . LEU A 1 18 ? 21.910 225.867 -4.254 1.00 43.54 ? 324 LEU A HD11 1 ATOM 252 H HD12 . LEU A 1 18 ? 22.337 224.767 -5.318 1.00 43.54 ? 324 LEU A HD12 1 ATOM 253 H HD13 . LEU A 1 18 ? 22.420 224.445 -3.764 1.00 43.54 ? 324 LEU A HD13 1 ATOM 254 H HD21 . LEU A 1 18 ? 23.591 227.065 -2.934 1.00 30.37 ? 324 LEU A HD21 1 ATOM 255 H HD22 . LEU A 1 18 ? 24.137 225.692 -2.348 1.00 30.37 ? 324 LEU A HD22 1 ATOM 256 H HD23 . LEU A 1 18 ? 25.130 226.695 -3.077 1.00 30.37 ? 324 LEU A HD23 1 ATOM 257 N N . PRO A 1 19 ? 27.569 223.137 -3.555 1.00 25.26 ? 325 PRO A N 1 ATOM 258 C CA . PRO A 1 19 ? 28.302 221.873 -3.457 1.00 29.29 ? 325 PRO A CA 1 ATOM 259 C C . PRO A 1 19 ? 27.434 220.694 -3.874 1.00 28.74 ? 325 PRO A C 1 ATOM 260 O O . PRO A 1 19 ? 26.203 220.765 -3.904 1.00 22.83 ? 325 PRO A O 1 ATOM 261 C CB . PRO A 1 19 ? 28.675 221.793 -1.973 1.00 29.01 ? 325 PRO A CB 1 ATOM 262 C CG . PRO A 1 19 ? 27.583 222.514 -1.290 1.00 27.77 ? 325 PRO A CG 1 ATOM 263 C CD . PRO A 1 19 ? 27.145 223.621 -2.230 1.00 28.83 ? 325 PRO A CD 1 ATOM 264 H HA . PRO A 1 19 ? 29.107 221.899 -3.998 1.00 35.14 ? 325 PRO A HA 1 ATOM 265 H HB2 . PRO A 1 19 ? 28.707 220.866 -1.690 1.00 34.81 ? 325 PRO A HB2 1 ATOM 266 H HB3 . PRO A 1 19 ? 29.527 222.232 -1.822 1.00 34.81 ? 325 PRO A HB3 1 ATOM 267 H HG2 . PRO A 1 19 ? 26.849 221.903 -1.120 1.00 33.33 ? 325 PRO A HG2 1 ATOM 268 H HG3 . PRO A 1 19 ? 27.914 222.887 -0.458 1.00 33.33 ? 325 PRO A HG3 1 ATOM 269 H HD2 . PRO A 1 19 ? 26.181 223.726 -2.202 1.00 34.59 ? 325 PRO A HD2 1 ATOM 270 H HD3 . PRO A 1 19 ? 27.600 224.449 -2.012 1.00 34.59 ? 325 PRO A HD3 1 ATOM 271 N N . ASP A 1 20 ? 28.107 219.603 -4.234 1.00 35.06 ? 326 ASP A N 1 ATOM 272 C CA . ASP A 1 20 ? 27.420 218.339 -4.472 1.00 32.59 ? 326 ASP A CA 1 ATOM 273 C C . ASP A 1 20 ? 26.900 217.785 -3.151 1.00 31.84 ? 326 ASP A C 1 ATOM 274 O O . ASP A 1 20 ? 27.535 217.944 -2.106 1.00 31.72 ? 326 ASP A O 1 ATOM 275 C CB . ASP A 1 20 ? 28.367 217.321 -5.113 1.00 38.62 ? 326 ASP A CB 1 ATOM 276 C CG . ASP A 1 20 ? 28.834 217.735 -6.499 1.00 45.38 ? 326 ASP A CG 1 ATOM 277 O OD1 . ASP A 1 20 ? 28.107 218.494 -7.180 1.00 48.18 ? 326 ASP A OD1 1 ATOM 278 O OD2 . ASP A 1 20 ? 29.929 217.284 -6.907 1.00 47.07 ? 326 ASP A OD2 1 ATOM 279 H H . ASP A 1 20 ? 28.959 219.570 -4.347 1.00 42.07 ? 326 ASP A H 1 ATOM 280 H HA . ASP A 1 20 ? 26.668 218.482 -5.067 1.00 39.11 ? 326 ASP A HA 1 ATOM 281 H HB2 . ASP A 1 20 ? 29.151 217.222 -4.551 1.00 46.34 ? 326 ASP A HB2 1 ATOM 282 H HB3 . ASP A 1 20 ? 27.908 216.471 -5.194 1.00 46.34 ? 326 ASP A HB3 1 ATOM 283 N N . CYS A 1 21 ? 25.736 217.125 -3.199 1.00 35.26 ? 327 CYS A N 1 ATOM 284 C CA . CYS A 1 21 ? 25.152 216.570 -1.979 1.00 29.67 ? 327 CYS A CA 1 ATOM 285 C C . CYS A 1 21 ? 25.937 215.364 -1.470 1.00 27.65 ? 327 CYS A C 1 ATOM 286 O O . CYS A 1 21 ? 25.948 215.104 -0.264 1.00 30.55 ? 327 CYS A O 1 ATOM 287 C CB . CYS A 1 21 ? 23.688 216.171 -2.209 1.00 30.00 ? 327 CYS A CB 1 ATOM 288 S SG . CYS A 1 21 ? 22.527 217.501 -2.702 1.00 34.74 ? 327 CYS A SG 1 ATOM 289 H H . CYS A 1 21 ? 25.275 216.988 -3.912 1.00 42.31 ? 327 CYS A H 1 ATOM 290 H HA . CYS A 1 21 ? 25.169 217.249 -1.286 1.00 35.61 ? 327 CYS A HA 1 ATOM 291 H HB2 . CYS A 1 21 ? 23.665 215.500 -2.909 1.00 35.99 ? 327 CYS A HB2 1 ATOM 292 H HB3 . CYS A 1 21 ? 23.347 215.786 -1.387 1.00 35.99 ? 327 CYS A HB3 1 ATOM 293 N N . ASP A 1 22 ? 26.588 214.615 -2.363 1.00 30.85 ? 328 ASP A N 1 ATOM 294 C CA . ASP A 1 22 ? 27.345 213.420 -1.979 1.00 33.84 ? 328 ASP A CA 1 ATOM 295 C C . ASP A 1 22 ? 26.467 212.411 -1.235 1.00 31.38 ? 328 ASP A C 1 ATOM 296 O O . ASP A 1 22 ? 26.872 211.817 -0.234 1.00 29.09 ? 328 ASP A O 1 ATOM 297 C CB . ASP A 1 22 ? 28.570 213.788 -1.135 1.00 38.77 ? 328 ASP A CB 1 ATOM 298 C CG . ASP A 1 22 ? 29.717 214.329 -1.973 1.00 40.21 ? 328 ASP A CG 1 ATOM 299 O OD1 . ASP A 1 22 ? 29.654 214.193 -3.213 1.00 34.67 ? 328 ASP A OD1 1 ATOM 300 O OD2 . ASP A 1 22 ? 30.681 214.875 -1.385 1.00 41.02 ? 328 ASP A OD2 1 ATOM 301 H H . ASP A 1 22 ? 26.607 214.780 -3.206 1.00 37.02 ? 328 ASP A H 1 ATOM 302 H HA . ASP A 1 22 ? 27.667 212.988 -2.786 1.00 40.61 ? 328 ASP A HA 1 ATOM 303 H HB2 . ASP A 1 22 ? 28.319 214.470 -0.493 1.00 46.53 ? 328 ASP A HB2 1 ATOM 304 H HB3 . ASP A 1 22 ? 28.885 212.995 -0.672 1.00 46.53 ? 328 ASP A HB3 1 ATOM 305 N N . ILE A 1 23 ? 25.256 212.196 -1.736 1.00 28.50 ? 329 ILE A N 1 ATOM 306 C CA . ILE A 1 23 ? 24.392 211.190 -1.131 1.00 28.69 ? 329 ILE A CA 1 ATOM 307 C C . ILE A 1 23 ? 25.042 209.811 -1.208 1.00 31.97 ? 329 ILE A C 1 ATOM 308 O O . ILE A 1 23 ? 24.988 209.028 -0.250 1.00 23.11 ? 329 ILE A O 1 ATOM 309 C CB . ILE A 1 23 ? 23.012 211.207 -1.809 1.00 28.41 ? 329 ILE A CB 1 ATOM 310 C CG1 . ILE A 1 23 ? 22.307 212.530 -1.489 1.00 26.13 ? 329 ILE A CG1 1 ATOM 311 C CG2 . ILE A 1 23 ? 22.185 209.985 -1.364 1.00 27.17 ? 329 ILE A CG2 1 ATOM 312 C CD1 . ILE A 1 23 ? 21.036 212.787 -2.286 1.00 25.55 ? 329 ILE A CD1 1 ATOM 313 H H . ILE A 1 23 ? 24.916 212.608 -2.410 1.00 34.20 ? 329 ILE A H 1 ATOM 314 H HA . ILE A 1 23 ? 24.266 211.407 -0.194 1.00 34.42 ? 329 ILE A HA 1 ATOM 315 H HB . ILE A 1 23 ? 23.142 211.155 -2.768 1.00 34.09 ? 329 ILE A HB 1 ATOM 316 H HG12 . ILE A 1 23 ? 22.069 212.534 -0.548 1.00 31.36 ? 329 ILE A HG12 1 ATOM 317 H HG13 . ILE A 1 23 ? 22.921 213.259 -1.672 1.00 31.36 ? 329 ILE A HG13 1 ATOM 318 H HG21 . ILE A 1 23 ? 21.319 210.014 -1.802 1.00 32.61 ? 329 ILE A HG21 1 ATOM 319 H HG22 . ILE A 1 23 ? 22.657 209.176 -1.617 1.00 32.61 ? 329 ILE A HG22 1 ATOM 320 H HG23 . ILE A 1 23 ? 22.070 210.015 -0.401 1.00 32.61 ? 329 ILE A HG23 1 ATOM 321 H HD11 . ILE A 1 23 ? 20.663 213.641 -2.018 1.00 30.66 ? 329 ILE A HD11 1 ATOM 322 H HD12 . ILE A 1 23 ? 21.255 212.803 -3.231 1.00 30.66 ? 329 ILE A HD12 1 ATOM 323 H HD13 . ILE A 1 23 ? 20.402 212.076 -2.105 1.00 30.66 ? 329 ILE A HD13 1 ATOM 324 N N . ASP A 1 24 ? 25.675 209.496 -2.344 1.00 28.40 ? 330 ASP A N 1 ATOM 325 C CA . ASP A 1 24 ? 26.267 208.171 -2.515 1.00 29.38 ? 330 ASP A CA 1 ATOM 326 C C . ASP A 1 24 ? 27.340 207.902 -1.466 1.00 29.94 ? 330 ASP A C 1 ATOM 327 O O . ASP A 1 24 ? 27.471 206.773 -0.973 1.00 23.69 ? 330 ASP A O 1 ATOM 328 C CB . ASP A 1 24 ? 26.846 208.024 -3.922 1.00 29.54 ? 330 ASP A CB 1 ATOM 329 C CG . ASP A 1 24 ? 27.932 209.038 -4.222 1.00 39.53 ? 330 ASP A CG 1 ATOM 330 O OD1 . ASP A 1 24 ? 27.625 210.250 -4.208 1.00 39.34 ? 330 ASP A OD1 1 ATOM 331 O OD2 . ASP A 1 24 ? 29.083 208.622 -4.491 1.00 43.58 ? 330 ASP A OD2 1 ATOM 332 H H . ASP A 1 24 ? 25.773 210.022 -3.017 1.00 34.08 ? 330 ASP A H 1 ATOM 333 H HA . ASP A 1 24 ? 25.573 207.502 -2.408 1.00 35.25 ? 330 ASP A HA 1 ATOM 334 H HB2 . ASP A 1 24 ? 27.230 207.138 -4.015 1.00 35.44 ? 330 ASP A HB2 1 ATOM 335 H HB3 . ASP A 1 24 ? 26.135 208.146 -4.571 1.00 35.44 ? 330 ASP A HB3 1 ATOM 336 N N . LYS A 1 25 ? 28.116 208.926 -1.105 1.00 30.91 ? 331 LYS A N 1 ATOM 337 C CA . LYS A 1 25 ? 29.179 208.730 -0.130 1.00 25.31 ? 331 LYS A CA 1 ATOM 338 C C . LYS A 1 25 ? 28.591 208.356 1.219 1.00 29.28 ? 331 LYS A C 1 ATOM 339 O O . LYS A 1 25 ? 29.170 207.563 1.968 1.00 27.89 ? 331 LYS A O 1 ATOM 340 C CB . LYS A 1 25 ? 30.029 209.999 -0.017 1.00 30.21 ? 331 LYS A CB 1 ATOM 341 C CG . LYS A 1 25 ? 30.812 210.388 -1.293 1.00 41.44 ? 331 LYS A CG 1 ATOM 342 C CD . LYS A 1 25 ? 31.442 209.156 -2.007 1.00 67.64 ? 331 LYS A CD 1 ATOM 343 C CE . LYS A 1 25 ? 32.382 208.323 -1.085 1.00 66.82 ? 331 LYS A CE 1 ATOM 344 N NZ . LYS A 1 25 ? 32.450 206.856 -1.419 1.00 44.80 ? 331 LYS A NZ 1 ATOM 345 H H . LYS A 1 25 ? 28.047 209.729 -1.406 1.00 37.10 ? 331 LYS A H 1 ATOM 346 H HA . LYS A 1 25 ? 29.752 208.005 -0.423 1.00 30.38 ? 331 LYS A HA 1 ATOM 347 H HB2 . LYS A 1 25 ? 29.445 210.741 0.204 1.00 36.25 ? 331 LYS A HB2 1 ATOM 348 H HB3 . LYS A 1 25 ? 30.675 209.872 0.694 1.00 36.25 ? 331 LYS A HB3 1 ATOM 349 H HG2 . LYS A 1 25 ? 30.208 210.821 -1.917 1.00 49.73 ? 331 LYS A HG2 1 ATOM 350 H HG3 . LYS A 1 25 ? 31.530 210.995 -1.051 1.00 49.73 ? 331 LYS A HG3 1 ATOM 351 H HD2 . LYS A 1 25 ? 30.730 208.572 -2.312 1.00 81.17 ? 331 LYS A HD2 1 ATOM 352 H HD3 . LYS A 1 25 ? 31.964 209.464 -2.764 1.00 81.17 ? 331 LYS A HD3 1 ATOM 353 H HE2 . LYS A 1 25 ? 33.281 208.682 -1.154 1.00 80.18 ? 331 LYS A HE2 1 ATOM 354 H HE3 . LYS A 1 25 ? 32.069 208.402 -0.170 1.00 80.18 ? 331 LYS A HE3 1 ATOM 355 H HZ1 . LYS A 1 25 ? 31.641 206.491 -1.352 1.00 53.76 ? 331 LYS A HZ1 1 ATOM 356 H HZ2 . LYS A 1 25 ? 32.748 206.747 -2.251 1.00 53.76 ? 331 LYS A HZ2 1 ATOM 357 H HZ3 . LYS A 1 25 ? 33.002 206.441 -0.857 1.00 53.76 ? 331 LYS A HZ3 1 ATOM 358 N N . TRP A 1 26 ? 27.428 208.912 1.543 1.00 25.95 ? 332 TRP A N 1 ATOM 359 C CA . TRP A 1 26 ? 26.816 208.613 2.822 1.00 28.67 ? 332 TRP A CA 1 ATOM 360 C C . TRP A 1 26 ? 26.201 207.217 2.829 1.00 23.94 ? 332 TRP A C 1 ATOM 361 O O . TRP A 1 26 ? 26.282 206.505 3.830 1.00 22.69 ? 332 TRP A O 1 ATOM 362 C CB . TRP A 1 26 ? 25.769 209.667 3.148 1.00 23.45 ? 332 TRP A CB 1 ATOM 363 C CG . TRP A 1 26 ? 25.200 209.495 4.525 1.00 28.72 ? 332 TRP A CG 1 ATOM 364 C CD1 . TRP A 1 26 ? 25.821 209.760 5.709 1.00 29.98 ? 332 TRP A CD1 1 ATOM 365 C CD2 . TRP A 1 26 ? 23.895 209.017 4.854 1.00 23.71 ? 332 TRP A CD2 1 ATOM 366 N NE1 . TRP A 1 26 ? 24.981 209.478 6.760 1.00 28.41 ? 332 TRP A NE1 1 ATOM 367 C CE2 . TRP A 1 26 ? 23.790 209.022 6.258 1.00 28.25 ? 332 TRP A CE2 1 ATOM 368 C CE3 . TRP A 1 26 ? 22.803 208.584 4.095 1.00 29.30 ? 332 TRP A CE3 1 ATOM 369 C CZ2 . TRP A 1 26 ? 22.638 208.621 6.917 1.00 26.58 ? 332 TRP A CZ2 1 ATOM 370 C CZ3 . TRP A 1 26 ? 21.670 208.173 4.748 1.00 27.54 ? 332 TRP A CZ3 1 ATOM 371 C CH2 . TRP A 1 26 ? 21.589 208.201 6.146 1.00 25.39 ? 332 TRP A CH2 1 ATOM 372 H H . TRP A 1 26 ? 26.982 209.456 1.046 1.00 31.14 ? 332 TRP A H 1 ATOM 373 H HA . TRP A 1 26 ? 27.497 208.644 3.512 1.00 34.40 ? 332 TRP A HA 1 ATOM 374 H HB2 . TRP A 1 26 ? 26.177 210.546 3.098 1.00 28.14 ? 332 TRP A HB2 1 ATOM 375 H HB3 . TRP A 1 26 ? 25.042 209.600 2.510 1.00 28.14 ? 332 TRP A HB3 1 ATOM 376 H HD1 . TRP A 1 26 ? 26.687 210.089 5.794 1.00 35.97 ? 332 TRP A HD1 1 ATOM 377 H HE1 . TRP A 1 26 ? 25.169 209.579 7.593 1.00 34.09 ? 332 TRP A HE1 1 ATOM 378 H HE3 . TRP A 1 26 ? 22.846 208.571 3.166 1.00 35.16 ? 332 TRP A HE3 1 ATOM 379 H HZ2 . TRP A 1 26 ? 22.585 208.624 7.845 1.00 31.90 ? 332 TRP A HZ2 1 ATOM 380 H HZ3 . TRP A 1 26 ? 20.934 207.891 4.254 1.00 33.05 ? 332 TRP A HZ3 1 ATOM 381 H HH2 . TRP A 1 26 ? 20.807 207.917 6.561 1.00 30.46 ? 332 TRP A HH2 1 ATOM 382 N N . LEU A 1 27 ? 25.559 206.820 1.731 1.00 21.38 ? 333 LEU A N 1 ATOM 383 C CA . LEU A 1 27 ? 24.965 205.495 1.674 1.00 23.12 ? 333 LEU A CA 1 ATOM 384 C C . LEU A 1 27 ? 26.026 204.406 1.693 1.00 24.49 ? 333 LEU A C 1 ATOM 385 O O . LEU A 1 27 ? 25.792 203.335 2.263 1.00 22.50 ? 333 LEU A O 1 ATOM 386 C CB . LEU A 1 27 ? 24.094 205.363 0.430 1.00 22.82 ? 333 LEU A CB 1 ATOM 387 C CG . LEU A 1 27 ? 22.773 206.129 0.472 1.00 23.10 ? 333 LEU A CG 1 ATOM 388 C CD1 . LEU A 1 27 ? 22.071 206.038 -0.877 1.00 25.74 ? 333 LEU A CD1 1 ATOM 389 C CD2 . LEU A 1 27 ? 21.874 205.624 1.595 1.00 23.00 ? 333 LEU A CD2 1 ATOM 390 H H . LEU A 1 27 ? 25.458 207.292 1.019 1.00 25.66 ? 333 LEU A H 1 ATOM 391 H HA . LEU A 1 27 ? 24.397 205.371 2.451 1.00 27.74 ? 333 LEU A HA 1 ATOM 392 H HB2 . LEU A 1 27 ? 24.597 205.689 -0.332 1.00 27.38 ? 333 LEU A HB2 1 ATOM 393 H HB3 . LEU A 1 27 ? 23.883 204.425 0.301 1.00 27.38 ? 333 LEU A HB3 1 ATOM 394 H HG . LEU A 1 27 ? 22.962 207.065 0.643 1.00 27.71 ? 333 LEU A HG 1 ATOM 395 H HD11 . LEU A 1 27 ? 21.236 206.529 -0.831 1.00 30.89 ? 333 LEU A HD11 1 ATOM 396 H HD12 . LEU A 1 27 ? 22.645 206.422 -1.558 1.00 30.89 ? 333 LEU A HD12 1 ATOM 397 H HD13 . LEU A 1 27 ? 21.896 205.105 -1.079 1.00 30.89 ? 333 LEU A HD13 1 ATOM 398 H HD21 . LEU A 1 27 ? 21.048 206.132 1.590 1.00 27.60 ? 333 LEU A HD21 1 ATOM 399 H HD22 . LEU A 1 27 ? 21.686 204.683 1.449 1.00 27.60 ? 333 LEU A HD22 1 ATOM 400 H HD23 . LEU A 1 27 ? 22.331 205.742 2.442 1.00 27.60 ? 333 LEU A HD23 1 ATOM 401 N N . ASN A 1 28 ? 27.189 204.662 1.095 1.00 21.38 ? 334 ASN A N 1 ATOM 402 C CA . ASN A 1 28 ? 28.238 203.663 0.968 1.00 26.16 ? 334 ASN A CA 1 ATOM 403 C C . ASN A 1 28 ? 29.203 203.650 2.142 1.00 25.97 ? 334 ASN A C 1 ATOM 404 O O . ASN A 1 28 ? 30.165 202.871 2.122 1.00 23.77 ? 334 ASN A O 1 ATOM 405 C CB . ASN A 1 28 ? 29.029 203.882 -0.321 1.00 24.65 ? 334 ASN A CB 1 ATOM 406 C CG . ASN A 1 28 ? 28.307 203.365 -1.538 1.00 24.46 ? 334 ASN A CG 1 ATOM 407 O OD1 . ASN A 1 28 ? 27.361 202.591 -1.429 1.00 27.33 ? 334 ASN A OD1 1 ATOM 408 N ND2 . ASN A 1 28 ? 28.753 203.786 -2.709 1.00 29.13 ? 334 ASN A ND2 1 ATOM 409 H H . ASN A 1 28 ? 27.394 205.422 0.749 1.00 25.66 ? 334 ASN A H 1 ATOM 410 H HA . ASN A 1 28 ? 27.826 202.786 0.916 1.00 31.40 ? 334 ASN A HA 1 ATOM 411 H HB2 . ASN A 1 28 ? 29.180 204.832 -0.442 1.00 29.58 ? 334 ASN A HB2 1 ATOM 412 H HB3 . ASN A 1 28 ? 29.878 203.416 -0.255 1.00 29.58 ? 334 ASN A HB3 1 ATOM 413 H HD21 . ASN A 1 28 ? 28.374 203.520 -3.434 1.00 34.96 ? 334 ASN A HD21 1 ATOM 414 H HD22 . ASN A 1 28 ? 29.421 204.326 -2.745 1.00 34.96 ? 334 ASN A HD22 1 ATOM 415 N N . ASN A 1 29 ? 28.969 204.476 3.157 1.00 21.54 ? 335 ASN A N 1 ATOM 416 C CA . ASN A 1 29 ? 29.771 204.417 4.374 1.00 24.87 ? 335 ASN A CA 1 ATOM 417 C C . ASN A 1 29 ? 29.779 203.000 4.922 1.00 25.41 ? 335 ASN A C 1 ATOM 418 O O . ASN A 1 29 ? 28.724 202.392 5.120 1.00 24.78 ? 335 ASN A O 1 ATOM 419 C CB . ASN A 1 29 ? 29.215 205.382 5.424 1.00 23.48 ? 335 ASN A CB 1 ATOM 420 C CG . ASN A 1 29 ? 30.146 205.558 6.603 1.00 28.30 ? 335 ASN A CG 1 ATOM 421 O OD1 . ASN A 1 29 ? 30.387 204.625 7.379 1.00 29.71 ? 335 ASN A OD1 1 ATOM 422 N ND2 . ASN A 1 29 ? 30.661 206.773 6.761 1.00 34.60 ? 335 ASN A ND2 1 ATOM 423 H H . ASN A 1 29 ? 28.354 205.078 3.166 1.00 25.85 ? 335 ASN A H 1 ATOM 424 H HA . ASN A 1 29 ? 30.684 204.675 4.172 1.00 29.84 ? 335 ASN A HA 1 ATOM 425 H HB2 . ASN A 1 29 ? 29.080 206.251 5.015 1.00 28.17 ? 335 ASN A HB2 1 ATOM 426 H HB3 . ASN A 1 29 ? 28.372 205.036 5.756 1.00 28.17 ? 335 ASN A HB3 1 ATOM 427 H HD21 . ASN A 1 29 ? 31.196 206.931 7.415 1.00 41.52 ? 335 ASN A HD21 1 ATOM 428 H HD22 . ASN A 1 29 ? 30.458 207.401 6.210 1.00 41.52 ? 335 ASN A HD22 1 ATOM 429 N N . PHE A 1 30 ? 30.980 202.478 5.165 1.00 26.05 ? 336 PHE A N 1 ATOM 430 C CA . PHE A 1 30 ? 31.122 201.087 5.576 1.00 27.09 ? 336 PHE A CA 1 ATOM 431 C C . PHE A 1 30 ? 30.613 200.831 6.988 1.00 28.19 ? 336 PHE A C 1 ATOM 432 O O . PHE A 1 30 ? 30.368 199.673 7.335 1.00 25.49 ? 336 PHE A O 1 ATOM 433 C CB . PHE A 1 30 ? 32.586 200.659 5.474 1.00 28.74 ? 336 PHE A CB 1 ATOM 434 C CG . PHE A 1 30 ? 33.086 200.517 4.061 1.00 37.38 ? 336 PHE A CG 1 ATOM 435 C CD1 . PHE A 1 30 ? 32.284 199.965 3.068 1.00 38.17 ? 336 PHE A CD1 1 ATOM 436 C CD2 . PHE A 1 30 ? 34.365 200.937 3.721 1.00 38.11 ? 336 PHE A CD2 1 ATOM 437 C CE1 . PHE A 1 30 ? 32.746 199.833 1.767 1.00 41.15 ? 336 PHE A CE1 1 ATOM 438 C CE2 . PHE A 1 30 ? 34.832 200.805 2.416 1.00 45.32 ? 336 PHE A CE2 1 ATOM 439 C CZ . PHE A 1 30 ? 34.020 200.255 1.442 1.00 40.02 ? 336 PHE A CZ 1 ATOM 440 H H . PHE A 1 30 ? 31.723 202.906 5.099 1.00 31.26 ? 336 PHE A H 1 ATOM 441 H HA . PHE A 1 30 ? 30.608 200.529 4.971 1.00 32.51 ? 336 PHE A HA 1 ATOM 442 H HB2 . PHE A 1 30 ? 33.137 201.323 5.917 1.00 34.49 ? 336 PHE A HB2 1 ATOM 443 H HB3 . PHE A 1 30 ? 32.691 199.800 5.912 1.00 34.49 ? 336 PHE A HB3 1 ATOM 444 H HD1 . PHE A 1 30 ? 31.424 199.679 3.280 1.00 45.80 ? 336 PHE A HD1 1 ATOM 445 H HD2 . PHE A 1 30 ? 34.916 201.308 4.372 1.00 45.73 ? 336 PHE A HD2 1 ATOM 446 H HE1 . PHE A 1 30 ? 32.198 199.463 1.114 1.00 49.38 ? 336 PHE A HE1 1 ATOM 447 H HE2 . PHE A 1 30 ? 35.690 201.089 2.199 1.00 54.38 ? 336 PHE A HE2 1 ATOM 448 H HZ . PHE A 1 30 ? 34.332 200.167 0.570 1.00 48.02 ? 336 PHE A HZ 1 ATOM 449 N N . ASN A 1 31 ? 30.449 201.870 7.807 1.00 26.85 ? 337 ASN A N 1 ATOM 450 C CA . ASN A 1 31 ? 29.873 201.718 9.146 1.00 31.31 ? 337 ASN A CA 1 ATOM 451 C C . ASN A 1 31 ? 28.362 201.793 9.000 1.00 29.93 ? 337 ASN A C 1 ATOM 452 O O . ASN A 1 31 ? 27.790 202.878 8.875 1.00 30.36 ? 337 ASN A O 1 ATOM 453 C CB . ASN A 1 31 ? 30.385 202.793 10.102 1.00 34.97 ? 337 ASN A CB 1 ATOM 454 C CG . ASN A 1 31 ? 31.807 202.559 10.527 1.00 46.15 ? 337 ASN A CG 1 ATOM 455 O OD1 . ASN A 1 31 ? 32.700 203.343 10.204 1.00 53.37 ? 337 ASN A OD1 1 ATOM 456 N ND2 . ASN A 1 31 ? 32.035 201.471 11.258 1.00 42.93 ? 337 ASN A ND2 1 ATOM 457 H H . ASN A 1 31 ? 30.664 202.679 7.611 1.00 32.22 ? 337 ASN A H 1 ATOM 458 H HA . ASN A 1 31 ? 30.107 200.848 9.505 1.00 37.57 ? 337 ASN A HA 1 ATOM 459 H HB2 . ASN A 1 31 ? 30.342 203.655 9.660 1.00 41.96 ? 337 ASN A HB2 1 ATOM 460 H HB3 . ASN A 1 31 ? 29.830 202.799 10.897 1.00 41.96 ? 337 ASN A HB3 1 ATOM 461 H HD21 . ASN A 1 31 ? 32.832 201.292 11.527 1.00 51.52 ? 337 ASN A HD21 1 ATOM 462 H HD22 . ASN A 1 31 ? 31.385 200.946 11.462 1.00 51.52 ? 337 ASN A HD22 1 ATOM 463 N N . VAL A 1 32 ? 27.706 200.644 9.007 1.00 25.02 ? 338 VAL A N 1 ATOM 464 C CA . VAL A 1 32 ? 26.299 200.548 8.629 1.00 23.36 ? 338 VAL A CA 1 ATOM 465 C C . VAL A 1 32 ? 25.476 200.313 9.890 1.00 18.73 ? 338 VAL A C 1 ATOM 466 O O . VAL A 1 32 ? 25.765 199.372 10.634 1.00 20.04 ? 338 VAL A O 1 ATOM 467 C CB . VAL A 1 32 ? 26.060 199.434 7.599 1.00 17.61 ? 338 VAL A CB 1 ATOM 468 C CG1 . VAL A 1 32 ? 24.592 199.397 7.208 1.00 20.68 ? 338 VAL A CG1 1 ATOM 469 C CG2 . VAL A 1 32 ? 26.941 199.680 6.405 1.00 21.45 ? 338 VAL A CG2 1 ATOM 470 H H . VAL A 1 32 ? 28.056 199.891 9.230 1.00 30.02 ? 338 VAL A H 1 ATOM 471 H HA . VAL A 1 32 ? 26.017 201.388 8.235 1.00 28.03 ? 338 VAL A HA 1 ATOM 472 H HB . VAL A 1 32 ? 26.298 198.577 7.987 1.00 21.14 ? 338 VAL A HB 1 ATOM 473 H HG11 . VAL A 1 32 ? 24.456 198.690 6.558 1.00 24.81 ? 338 VAL A HG11 1 ATOM 474 H HG12 . VAL A 1 32 ? 24.059 199.226 8.000 1.00 24.81 ? 338 VAL A HG12 1 ATOM 475 H HG13 . VAL A 1 32 ? 24.347 200.253 6.822 1.00 24.81 ? 338 VAL A HG13 1 ATOM 476 H HG21 . VAL A 1 32 ? 26.793 198.978 5.753 1.00 25.74 ? 338 VAL A HG21 1 ATOM 477 H HG22 . VAL A 1 32 ? 26.718 200.542 6.021 1.00 25.74 ? 338 VAL A HG22 1 ATOM 478 H HG23 . VAL A 1 32 ? 27.868 199.676 6.691 1.00 25.74 ? 338 VAL A HG23 1 ATOM 479 N N . PRO A 1 33 ? 24.454 201.117 10.154 1.00 16.59 ? 339 PRO A N 1 ATOM 480 C CA . PRO A 1 33 ? 23.654 200.909 11.361 1.00 18.30 ? 339 PRO A CA 1 ATOM 481 C C . PRO A 1 33 ? 22.581 199.856 11.153 1.00 19.65 ? 339 PRO A C 1 ATOM 482 O O . PRO A 1 33 ? 22.137 199.592 10.035 1.00 16.72 ? 339 PRO A O 1 ATOM 483 C CB . PRO A 1 33 ? 23.033 202.289 11.610 1.00 17.41 ? 339 PRO A CB 1 ATOM 484 C CG . PRO A 1 33 ? 22.874 202.852 10.187 1.00 21.70 ? 339 PRO A CG 1 ATOM 485 C CD . PRO A 1 33 ? 24.077 202.361 9.447 1.00 18.73 ? 339 PRO A CD 1 ATOM 486 H HA . PRO A 1 33 ? 24.219 200.663 12.110 1.00 21.96 ? 339 PRO A HA 1 ATOM 487 H HB2 . PRO A 1 33 ? 22.172 202.194 12.047 1.00 20.89 ? 339 PRO A HB2 1 ATOM 488 H HB3 . PRO A 1 33 ? 23.636 202.836 12.137 1.00 20.89 ? 339 PRO A HB3 1 ATOM 489 H HG2 . PRO A 1 33 ? 22.060 202.507 9.787 1.00 26.05 ? 339 PRO A HG2 1 ATOM 490 H HG3 . PRO A 1 33 ? 22.860 203.821 10.217 1.00 26.05 ? 339 PRO A HG3 1 ATOM 491 H HD2 . PRO A 1 33 ? 23.848 202.168 8.525 1.00 22.48 ? 339 PRO A HD2 1 ATOM 492 H HD3 . PRO A 1 33 ? 24.795 203.011 9.504 1.00 22.48 ? 339 PRO A HD3 1 ATOM 493 N N . SER A 1 34 ? 22.182 199.241 12.264 1.00 20.44 ? 340 SER A N 1 ATOM 494 C CA . SER A 1 34 ? 21.039 198.350 12.291 1.00 16.70 ? 340 SER A CA 1 ATOM 495 C C . SER A 1 34 ? 19.746 199.162 12.321 1.00 15.63 ? 340 SER A C 1 ATOM 496 O O . SER A 1 34 ? 19.741 200.336 12.703 1.00 15.92 ? 340 SER A O 1 ATOM 497 C CB . SER A 1 34 ? 21.110 197.442 13.522 1.00 18.96 ? 340 SER A CB 1 ATOM 498 O OG . SER A 1 34 ? 20.330 197.973 14.584 1.00 17.89 ? 340 SER A OG 1 ATOM 499 H H . SER A 1 34 ? 22.569 199.330 13.027 1.00 24.53 ? 340 SER A H 1 ATOM 500 H HA . SER A 1 34 ? 21.038 197.795 11.495 1.00 20.04 ? 340 SER A HA 1 ATOM 501 H HB2 . SER A 1 34 ? 20.769 196.564 13.288 1.00 22.76 ? 340 SER A HB2 1 ATOM 502 H HB3 . SER A 1 34 ? 22.033 197.373 13.812 1.00 22.76 ? 340 SER A HB3 1 ATOM 503 H HG . SER A 1 34 ? 20.614 198.734 14.796 1.00 21.47 ? 340 SER A HG 1 ATOM 504 N N . PRO A 1 35 ? 18.620 198.554 11.961 1.00 12.23 ? 341 PRO A N 1 ATOM 505 C CA . PRO A 1 35 ? 17.350 199.286 12.075 1.00 13.53 ? 341 PRO A CA 1 ATOM 506 C C . PRO A 1 35 ? 17.063 199.787 13.484 1.00 15.59 ? 341 PRO A C 1 ATOM 507 O O . PRO A 1 35 ? 16.338 200.780 13.646 1.00 11.75 ? 341 PRO A O 1 ATOM 508 C CB . PRO A 1 35 ? 16.311 198.262 11.611 1.00 14.84 ? 341 PRO A CB 1 ATOM 509 C CG . PRO A 1 35 ? 16.993 196.923 11.698 1.00 18.36 ? 341 PRO A CG 1 ATOM 510 C CD . PRO A 1 35 ? 18.440 197.172 11.482 1.00 15.17 ? 341 PRO A CD 1 ATOM 511 H HA . PRO A 1 35 ? 17.346 200.040 11.465 1.00 16.23 ? 341 PRO A HA 1 ATOM 512 H HB2 . PRO A 1 35 ? 15.540 198.291 12.198 1.00 17.81 ? 341 PRO A HB2 1 ATOM 513 H HB3 . PRO A 1 35 ? 16.052 198.454 10.696 1.00 17.81 ? 341 PRO A HB3 1 ATOM 514 H HG2 . PRO A 1 35 ? 16.842 196.540 12.577 1.00 22.04 ? 341 PRO A HG2 1 ATOM 515 H HG3 . PRO A 1 35 ? 16.643 196.337 11.009 1.00 22.04 ? 341 PRO A HG3 1 ATOM 516 H HD2 . PRO A 1 35 ? 18.972 196.558 12.012 1.00 18.20 ? 341 PRO A HD2 1 ATOM 517 H HD3 . PRO A 1 35 ? 18.657 197.110 10.539 1.00 18.20 ? 341 PRO A HD3 1 ATOM 518 N N . LEU A 1 36 ? 17.617 199.134 14.509 1.00 14.30 ? 342 LEU A N 1 ATOM 519 C CA . LEU A 1 36 ? 17.403 199.590 15.880 1.00 14.84 ? 342 LEU A CA 1 ATOM 520 C C . LEU A 1 36 ? 17.887 201.026 16.060 1.00 13.42 ? 342 LEU A C 1 ATOM 521 O O . LEU A 1 36 ? 17.170 201.869 16.609 1.00 12.05 ? 342 LEU A O 1 ATOM 522 C CB . LEU A 1 36 ? 18.110 198.645 16.864 1.00 15.19 ? 342 LEU A CB 1 ATOM 523 C CG . LEU A 1 36 ? 17.899 198.949 18.347 1.00 17.18 ? 342 LEU A CG 1 ATOM 524 C CD1 . LEU A 1 36 ? 16.437 198.808 18.692 1.00 18.03 ? 342 LEU A CD1 1 ATOM 525 C CD2 . LEU A 1 36 ? 18.757 198.058 19.245 1.00 15.21 ? 342 LEU A CD2 1 ATOM 526 H H . LEU A 1 36 ? 18.113 198.436 14.438 1.00 17.16 ? 342 LEU A H 1 ATOM 527 H HA . LEU A 1 36 ? 16.453 199.568 16.074 1.00 17.81 ? 342 LEU A HA 1 ATOM 528 H HB2 . LEU A 1 36 ? 17.790 197.743 16.705 1.00 18.23 ? 342 LEU A HB2 1 ATOM 529 H HB3 . LEU A 1 36 ? 19.064 198.683 16.693 1.00 18.23 ? 342 LEU A HB3 1 ATOM 530 H HG . LEU A 1 36 ? 18.155 199.870 18.514 1.00 20.62 ? 342 LEU A HG 1 ATOM 531 H HD11 . LEU A 1 36 ? 16.316 199.004 19.634 1.00 21.64 ? 342 LEU A HD11 1 ATOM 532 H HD12 . LEU A 1 36 ? 15.925 199.433 18.155 1.00 21.64 ? 342 LEU A HD12 1 ATOM 533 H HD13 . LEU A 1 36 ? 16.155 197.900 18.503 1.00 21.64 ? 342 LEU A HD13 1 ATOM 534 H HD21 . LEU A 1 36 ? 18.589 198.289 20.172 1.00 18.25 ? 342 LEU A HD21 1 ATOM 535 H HD22 . LEU A 1 36 ? 18.522 197.131 19.086 1.00 18.25 ? 342 LEU A HD22 1 ATOM 536 H HD23 . LEU A 1 36 ? 19.693 198.203 19.032 1.00 18.25 ? 342 LEU A HD23 1 ATOM 537 N N . ASN A 1 37 ? 19.104 201.320 15.597 1.00 16.74 ? 343 ASN A N 1 ATOM 538 C CA . ASN A 1 37 ? 19.657 202.674 15.604 1.00 15.73 ? 343 ASN A CA 1 ATOM 539 C C . ASN A 1 37 ? 19.717 203.301 14.209 1.00 17.84 ? 343 ASN A C 1 ATOM 540 O O . ASN A 1 37 ? 20.774 203.793 13.808 1.00 14.12 ? 343 ASN A O 1 ATOM 541 C CB . ASN A 1 37 ? 21.069 202.667 16.208 1.00 15.32 ? 343 ASN A CB 1 ATOM 542 C CG . ASN A 1 37 ? 21.981 201.592 15.607 1.00 17.57 ? 343 ASN A CG 1 ATOM 543 O OD1 . ASN A 1 37 ? 21.754 200.400 15.792 1.00 18.03 ? 343 ASN A OD1 1 ATOM 544 N ND2 . ASN A 1 37 ? 23.052 202.018 14.953 1.00 14.56 ? 343 ASN A ND2 1 ATOM 545 H H . ASN A 1 37 ? 19.641 200.736 15.264 1.00 20.09 ? 343 ASN A H 1 ATOM 546 H HA . ASN A 1 37 ? 19.097 203.238 16.160 1.00 18.87 ? 343 ASN A HA 1 ATOM 547 H HB2 . ASN A 1 37 ? 21.482 203.530 16.051 1.00 18.38 ? 343 ASN A HB2 1 ATOM 548 H HB3 . ASN A 1 37 ? 21.002 202.502 17.162 1.00 18.38 ? 343 ASN A HB3 1 ATOM 549 H HD21 . ASN A 1 37 ? 23.593 201.452 14.598 1.00 17.48 ? 343 ASN A HD21 1 ATOM 550 H HD22 . ASN A 1 37 ? 23.206 202.862 14.883 1.00 17.48 ? 343 ASN A HD22 1 ATOM 551 N N . TRP A 1 38 ? 18.605 203.304 13.469 1.00 15.29 ? 344 TRP A N 1 ATOM 552 C CA . TRP A 1 38 ? 18.621 203.868 12.121 1.00 15.98 ? 344 TRP A CA 1 ATOM 553 C C . TRP A 1 38 ? 19.136 205.298 12.114 1.00 18.77 ? 344 TRP A C 1 ATOM 554 O O . TRP A 1 38 ? 18.798 206.111 12.982 1.00 15.68 ? 344 TRP A O 1 ATOM 555 C CB . TRP A 1 38 ? 17.238 203.824 11.468 1.00 12.91 ? 344 TRP A CB 1 ATOM 556 C CG . TRP A 1 38 ? 16.097 204.487 12.164 1.00 9.31 ? 344 TRP A CG 1 ATOM 557 C CD1 . TRP A 1 38 ? 15.239 203.913 13.030 1.00 13.67 ? 344 TRP A CD1 1 ATOM 558 C CD2 . TRP A 1 38 ? 15.647 205.837 11.990 1.00 18.71 ? 344 TRP A CD2 1 ATOM 559 N NE1 . TRP A 1 38 ? 14.282 204.807 13.425 1.00 13.50 ? 344 TRP A NE1 1 ATOM 560 C CE2 . TRP A 1 38 ? 14.513 206.004 12.801 1.00 15.94 ? 344 TRP A CE2 1 ATOM 561 C CE3 . TRP A 1 38 ? 16.086 206.918 11.213 1.00 21.20 ? 344 TRP A CE3 1 ATOM 562 C CZ2 . TRP A 1 38 ? 13.808 207.214 12.865 1.00 15.03 ? 344 TRP A CZ2 1 ATOM 563 C CZ3 . TRP A 1 38 ? 15.397 208.111 11.288 1.00 17.82 ? 344 TRP A CZ3 1 ATOM 564 C CH2 . TRP A 1 38 ? 14.274 208.250 12.112 1.00 18.14 ? 344 TRP A CH2 1 ATOM 565 H H . TRP A 1 38 ? 17.843 202.992 13.720 1.00 18.35 ? 344 TRP A H 1 ATOM 566 H HA . TRP A 1 38 ? 19.220 203.338 11.573 1.00 19.18 ? 344 TRP A HA 1 ATOM 567 H HB2 . TRP A 1 38 ? 17.310 204.239 10.594 1.00 15.50 ? 344 TRP A HB2 1 ATOM 568 H HB3 . TRP A 1 38 ? 16.993 202.892 11.355 1.00 15.50 ? 344 TRP A HB3 1 ATOM 569 H HD1 . TRP A 1 38 ? 15.290 203.031 13.320 1.00 16.41 ? 344 TRP A HD1 1 ATOM 570 H HE1 . TRP A 1 38 ? 13.649 204.649 13.985 1.00 16.21 ? 344 TRP A HE1 1 ATOM 571 H HE3 . TRP A 1 38 ? 16.830 206.834 10.661 1.00 25.44 ? 344 TRP A HE3 1 ATOM 572 H HZ2 . TRP A 1 38 ? 13.067 207.313 13.417 1.00 18.04 ? 344 TRP A HZ2 1 ATOM 573 H HZ3 . TRP A 1 38 ? 15.686 208.837 10.785 1.00 21.38 ? 344 TRP A HZ3 1 ATOM 574 H HH2 . TRP A 1 38 ? 13.834 209.069 12.145 1.00 21.76 ? 344 TRP A HH2 1 ATOM 575 N N . GLU A 1 39 ? 19.968 205.581 11.119 1.00 11.35 ? 345 GLU A N 1 ATOM 576 C CA . GLU A 1 39 ? 20.631 206.862 10.969 1.00 17.30 ? 345 GLU A CA 1 ATOM 577 C C . GLU A 1 39 ? 19.922 207.730 9.932 1.00 18.30 ? 345 GLU A C 1 ATOM 578 O O . GLU A 1 39 ? 19.415 207.231 8.921 1.00 21.49 ? 345 GLU A O 1 ATOM 579 C CB . GLU A 1 39 ? 22.093 206.656 10.571 1.00 16.70 ? 345 GLU A CB 1 ATOM 580 C CG . GLU A 1 39 ? 22.925 206.046 11.673 1.00 14.25 ? 345 GLU A CG 1 ATOM 581 C CD . GLU A 1 39 ? 24.321 205.717 11.239 1.00 19.71 ? 345 GLU A CD 1 ATOM 582 O OE1 . GLU A 1 39 ? 24.703 206.080 10.104 1.00 23.57 ? 345 GLU A OE1 1 ATOM 583 O OE2 . GLU A 1 39 ? 25.032 205.072 12.032 1.00 20.90 ? 345 GLU A OE2 1 ATOM 584 H H . GLU A 1 39 ? 20.168 205.023 10.496 1.00 13.62 ? 345 GLU A H 1 ATOM 585 H HA . GLU A 1 39 ? 20.613 207.331 11.818 1.00 20.76 ? 345 GLU A HA 1 ATOM 586 H HB2 . GLU A 1 39 ? 22.129 206.062 9.805 1.00 20.04 ? 345 GLU A HB2 1 ATOM 587 H HB3 . GLU A 1 39 ? 22.481 207.515 10.343 1.00 20.04 ? 345 GLU A HB3 1 ATOM 588 H HG2 . GLU A 1 39 ? 22.982 206.675 12.410 1.00 17.10 ? 345 GLU A HG2 1 ATOM 589 H HG3 . GLU A 1 39 ? 22.503 205.225 11.970 1.00 17.10 ? 345 GLU A HG3 1 ATOM 590 N N . ARG A 1 40 ? 19.888 209.031 10.197 1.00 19.99 ? 346 ARG A N 1 ATOM 591 C CA . ARG A 1 40 ? 19.224 210.006 9.343 1.00 16.82 ? 346 ARG A CA 1 ATOM 592 C C . ARG A 1 40 ? 20.194 211.106 8.962 1.00 19.53 ? 346 ARG A C 1 ATOM 593 O O . ARG A 1 40 ? 20.915 211.629 9.816 1.00 19.68 ? 346 ARG A O 1 ATOM 594 C CB . ARG A 1 40 ? 18.018 210.634 10.039 1.00 15.20 ? 346 ARG A CB 1 ATOM 595 C CG . ARG A 1 40 ? 17.555 211.930 9.416 1.00 18.94 ? 346 ARG A CG 1 ATOM 596 C CD . ARG A 1 40 ? 16.175 212.299 9.904 1.00 11.54 ? 346 ARG A CD 1 ATOM 597 N NE . ARG A 1 40 ? 15.163 211.346 9.463 1.00 19.89 ? 346 ARG A NE 1 ATOM 598 C CZ . ARG A 1 40 ? 13.868 211.491 9.707 1.00 24.54 ? 346 ARG A CZ 1 ATOM 599 N NH1 . ARG A 1 40 ? 13.438 212.549 10.386 1.00 19.24 ? 346 ARG A NH1 1 ATOM 600 N NH2 . ARG A 1 40 ? 13.000 210.597 9.269 1.00 18.38 ? 346 ARG A NH2 1 ATOM 601 H H . ARG A 1 40 ? 20.255 209.384 10.890 1.00 23.99 ? 346 ARG A H 1 ATOM 602 H HA . ARG A 1 40 ? 18.919 209.570 8.532 1.00 20.19 ? 346 ARG A HA 1 ATOM 603 H HB2 . ARG A 1 40 ? 17.278 210.009 10.005 1.00 18.24 ? 346 ARG A HB2 1 ATOM 604 H HB3 . ARG A 1 40 ? 18.251 210.817 10.963 1.00 18.24 ? 346 ARG A HB3 1 ATOM 605 H HG2 . ARG A 1 40 ? 18.167 212.642 9.661 1.00 22.73 ? 346 ARG A HG2 1 ATOM 606 H HG3 . ARG A 1 40 ? 17.522 211.831 8.452 1.00 22.73 ? 346 ARG A HG3 1 ATOM 607 H HD2 . ARG A 1 40 ? 16.174 212.314 10.873 1.00 13.85 ? 346 ARG A HD2 1 ATOM 608 H HD3 . ARG A 1 40 ? 15.938 213.173 9.556 1.00 13.85 ? 346 ARG A HD3 1 ATOM 609 H HE . ARG A 1 40 ? 15.402 210.733 8.909 1.00 23.86 ? 346 ARG A HE 1 ATOM 610 H HH11 . ARG A 1 40 ? 13.999 213.136 10.669 1.00 23.09 ? 346 ARG A HH11 1 ATOM 611 H HH12 . ARG A 1 40 ? 12.598 212.646 10.545 1.00 23.09 ? 346 ARG A HH12 1 ATOM 612 H HH21 . ARG A 1 40 ? 13.275 209.910 8.830 1.00 22.05 ? 346 ARG A HH21 1 ATOM 613 H HH22 . ARG A 1 40 ? 12.162 210.695 9.433 1.00 22.05 ? 346 ARG A HH22 1 ATOM 614 N N . LYS A 1 41 ? 20.202 211.466 7.674 1.00 26.17 ? 347 LYS A N 1 ATOM 615 C CA . LYS A 1 41 ? 20.909 212.655 7.210 1.00 25.09 ? 347 LYS A CA 1 ATOM 616 C C . LYS A 1 41 ? 20.002 213.473 6.301 1.00 24.07 ? 347 LYS A C 1 ATOM 617 O O . LYS A 1 41 ? 19.352 212.932 5.399 1.00 16.51 ? 347 LYS A O 1 ATOM 618 C CB . LYS A 1 41 ? 22.205 212.292 6.490 1.00 22.52 ? 347 LYS A CB 1 ATOM 619 C CG . LYS A 1 41 ? 22.961 213.520 6.005 1.00 31.85 ? 347 LYS A CG 1 ATOM 620 C CD . LYS A 1 41 ? 24.408 213.213 5.664 1.00 35.55 ? 347 LYS A CD 1 ATOM 621 C CE . LYS A 1 41 ? 25.193 214.497 5.434 1.00 37.96 ? 347 LYS A CE 1 ATOM 622 N NZ . LYS A 1 41 ? 26.620 214.195 5.145 1.00 55.39 ? 347 LYS A NZ 1 ATOM 623 H H . LYS A 1 41 ? 19.802 211.032 7.049 1.00 31.41 ? 347 LYS A H 1 ATOM 624 H HA . LYS A 1 41 ? 21.137 213.204 7.976 1.00 30.11 ? 347 LYS A HA 1 ATOM 625 H HB2 . LYS A 1 41 ? 22.781 211.804 7.099 1.00 27.03 ? 347 LYS A HB2 1 ATOM 626 H HB3 . LYS A 1 41 ? 21.996 211.743 5.718 1.00 27.03 ? 347 LYS A HB3 1 ATOM 627 H HG2 . LYS A 1 41 ? 22.530 213.864 5.208 1.00 38.22 ? 347 LYS A HG2 1 ATOM 628 H HG3 . LYS A 1 41 ? 22.953 214.193 6.704 1.00 38.22 ? 347 LYS A HG3 1 ATOM 629 H HD2 . LYS A 1 41 ? 24.817 212.731 6.399 1.00 42.66 ? 347 LYS A HD2 1 ATOM 630 H HD3 . LYS A 1 41 ? 24.442 212.684 4.852 1.00 42.66 ? 347 LYS A HD3 1 ATOM 631 H HE2 . LYS A 1 41 ? 24.819 214.972 4.675 1.00 45.55 ? 347 LYS A HE2 1 ATOM 632 H HE3 . LYS A 1 41 ? 25.151 215.047 6.232 1.00 45.55 ? 347 LYS A HE3 1 ATOM 633 H HZ1 . LYS A 1 41 ? 27.069 214.952 5.012 1.00 66.47 ? 347 LYS A HZ1 1 ATOM 634 H HZ2 . LYS A 1 41 ? 26.983 213.759 5.830 1.00 66.47 ? 347 LYS A HZ2 1 ATOM 635 H HZ3 . LYS A 1 41 ? 26.681 213.690 4.414 1.00 66.47 ? 347 LYS A HZ3 1 ATOM 636 N N . ILE A 1 42 ? 19.950 214.774 6.554 1.00 25.81 ? 348 ILE A N 1 ATOM 637 C CA . ILE A 1 42 ? 19.141 215.701 5.767 1.00 27.96 ? 348 ILE A CA 1 ATOM 638 C C . ILE A 1 42 ? 20.030 216.400 4.748 1.00 22.76 ? 348 ILE A C 1 ATOM 639 O O . ILE A 1 42 ? 21.062 216.978 5.103 1.00 28.78 ? 348 ILE A O 1 ATOM 640 C CB . ILE A 1 42 ? 18.434 216.720 6.671 1.00 26.49 ? 348 ILE A CB 1 ATOM 641 C CG1 . ILE A 1 42 ? 17.608 215.972 7.731 1.00 26.57 ? 348 ILE A CG1 1 ATOM 642 C CG2 . ILE A 1 42 ? 17.554 217.625 5.830 1.00 21.50 ? 348 ILE A CG2 1 ATOM 643 C CD1 . ILE A 1 42 ? 16.947 216.878 8.760 1.00 22.17 ? 348 ILE A CD1 1 ATOM 644 H H . ILE A 1 42 ? 20.385 215.155 7.191 1.00 30.97 ? 348 ILE A H 1 ATOM 645 H HA . ILE A 1 42 ? 18.463 215.202 5.285 1.00 33.55 ? 348 ILE A HA 1 ATOM 646 H HB . ILE A 1 42 ? 19.104 217.261 7.119 1.00 31.78 ? 348 ILE A HB 1 ATOM 647 H HG12 . ILE A 1 42 ? 16.907 215.472 7.284 1.00 31.88 ? 348 ILE A HG12 1 ATOM 648 H HG13 . ILE A 1 42 ? 18.193 215.362 8.208 1.00 31.88 ? 348 ILE A HG13 1 ATOM 649 H HG21 . ILE A 1 42 ? 17.113 218.264 6.411 1.00 25.79 ? 348 ILE A HG21 1 ATOM 650 H HG22 . ILE A 1 42 ? 18.107 218.091 5.184 1.00 25.79 ? 348 ILE A HG22 1 ATOM 651 H HG23 . ILE A 1 42 ? 16.893 217.083 5.371 1.00 25.79 ? 348 ILE A HG23 1 ATOM 652 H HD11 . ILE A 1 42 ? 16.449 216.331 9.388 1.00 26.61 ? 348 ILE A HD11 1 ATOM 653 H HD12 . ILE A 1 42 ? 17.634 217.377 9.229 1.00 26.61 ? 348 ILE A HD12 1 ATOM 654 H HD13 . ILE A 1 42 ? 16.346 217.488 8.304 1.00 26.61 ? 348 ILE A HD13 1 ATOM 655 N N . PHE A 1 43 ? 19.632 216.345 3.483 1.00 23.79 ? 349 PHE A N 1 ATOM 656 C CA . PHE A 1 43 ? 20.370 216.968 2.392 1.00 24.93 ? 349 PHE A CA 1 ATOM 657 C C . PHE A 1 43 ? 19.617 218.203 1.930 1.00 23.80 ? 349 PHE A C 1 ATOM 658 O O . PHE A 1 43 ? 18.428 218.127 1.612 1.00 26.97 ? 349 PHE A O 1 ATOM 659 C CB . PHE A 1 43 ? 20.573 215.992 1.234 1.00 20.32 ? 349 PHE A CB 1 ATOM 660 C CG . PHE A 1 43 ? 21.491 214.854 1.579 1.00 21.03 ? 349 PHE A CG 1 ATOM 661 C CD1 . PHE A 1 43 ? 21.003 213.717 2.190 1.00 19.23 ? 349 PHE A CD1 1 ATOM 662 C CD2 . PHE A 1 43 ? 22.849 214.947 1.342 1.00 20.50 ? 349 PHE A CD2 1 ATOM 663 C CE1 . PHE A 1 43 ? 21.849 212.691 2.532 1.00 20.77 ? 349 PHE A CE1 1 ATOM 664 C CE2 . PHE A 1 43 ? 23.694 213.924 1.685 1.00 21.74 ? 349 PHE A CE2 1 ATOM 665 C CZ . PHE A 1 43 ? 23.189 212.794 2.283 1.00 26.33 ? 349 PHE A CZ 1 ATOM 666 H H . PHE A 1 43 ? 18.919 215.940 3.224 1.00 28.54 ? 349 PHE A H 1 ATOM 667 H HA . PHE A 1 43 ? 21.242 217.245 2.713 1.00 29.92 ? 349 PHE A HA 1 ATOM 668 H HB2 . PHE A 1 43 ? 19.714 215.618 0.983 1.00 24.38 ? 349 PHE A HB2 1 ATOM 669 H HB3 . PHE A 1 43 ? 20.959 216.470 0.483 1.00 24.38 ? 349 PHE A HB3 1 ATOM 670 H HD1 . PHE A 1 43 ? 20.093 213.642 2.366 1.00 23.08 ? 349 PHE A HD1 1 ATOM 671 H HD2 . PHE A 1 43 ? 23.194 215.712 0.941 1.00 24.60 ? 349 PHE A HD2 1 ATOM 672 H HE1 . PHE A 1 43 ? 21.509 211.925 2.935 1.00 24.92 ? 349 PHE A HE1 1 ATOM 673 H HE2 . PHE A 1 43 ? 24.605 213.992 1.512 1.00 26.08 ? 349 PHE A HE2 1 ATOM 674 H HZ . PHE A 1 43 ? 23.758 212.094 2.510 1.00 31.60 ? 349 PHE A HZ 1 ATOM 675 N N . SER A 1 44 ? 20.311 219.335 1.904 1.00 19.01 ? 350 SER A N 1 ATOM 676 C CA . SER A 1 44 ? 19.695 220.606 1.554 1.00 23.96 ? 350 SER A CA 1 ATOM 677 C C . SER A 1 44 ? 20.718 221.470 0.846 1.00 25.80 ? 350 SER A C 1 ATOM 678 O O . SER A 1 44 ? 21.925 221.338 1.068 1.00 27.64 ? 350 SER A O 1 ATOM 679 C CB . SER A 1 44 ? 19.178 221.363 2.781 1.00 23.15 ? 350 SER A CB 1 ATOM 680 O OG . SER A 1 44 ? 18.016 222.085 2.455 1.00 44.33 ? 350 SER A OG 1 ATOM 681 H H . SER A 1 44 ? 21.149 219.393 2.087 1.00 22.81 ? 350 SER A H 1 ATOM 682 H HA . SER A 1 44 ? 18.951 220.451 0.951 1.00 28.76 ? 350 SER A HA 1 ATOM 683 H HB2 . SER A 1 44 ? 18.970 220.727 3.483 1.00 27.78 ? 350 SER A HB2 1 ATOM 684 H HB3 . SER A 1 44 ? 19.862 221.982 3.084 1.00 27.78 ? 350 SER A HB3 1 ATOM 685 H HG . SER A 1 44 ? 17.417 221.560 2.189 1.00 53.19 ? 350 SER A HG 1 ATOM 686 N N . ASN A 1 45 ? 20.218 222.360 -0.010 1.00 27.18 ? 351 ASN A N 1 ATOM 687 C CA . ASN A 1 45 ? 21.036 223.420 -0.587 1.00 25.10 ? 351 ASN A CA 1 ATOM 688 C C . ASN A 1 45 ? 22.254 222.833 -1.291 1.00 24.22 ? 351 ASN A C 1 ATOM 689 O O . ASN A 1 45 ? 23.395 223.230 -1.046 1.00 25.43 ? 351 ASN A O 1 ATOM 690 C CB . ASN A 1 45 ? 21.450 224.424 0.496 1.00 27.06 ? 351 ASN A CB 1 ATOM 691 C CG . ASN A 1 45 ? 21.704 225.813 -0.060 1.00 33.01 ? 351 ASN A CG 1 ATOM 692 O OD1 . ASN A 1 45 ? 20.890 226.348 -0.807 1.00 34.98 ? 351 ASN A OD1 1 ATOM 693 N ND2 . ASN A 1 45 ? 22.842 226.399 0.299 1.00 30.07 ? 351 ASN A ND2 1 ATOM 694 H H . ASN A 1 45 ? 19.399 222.370 -0.273 1.00 32.62 ? 351 ASN A H 1 ATOM 695 H HA . ASN A 1 45 ? 20.510 223.896 -1.249 1.00 30.12 ? 351 ASN A HA 1 ATOM 696 H HB2 . ASN A 1 45 ? 20.740 224.490 1.154 1.00 32.47 ? 351 ASN A HB2 1 ATOM 697 H HB3 . ASN A 1 45 ? 22.267 224.115 0.918 1.00 32.47 ? 351 ASN A HB3 1 ATOM 698 H HD21 . ASN A 1 45 ? 23.029 227.186 0.008 1.00 36.08 ? 351 ASN A HD21 1 ATOM 699 H HD22 . ASN A 1 45 ? 23.390 225.991 0.821 1.00 36.08 ? 351 ASN A HD22 1 ATOM 700 N N . CYS A 1 46 ? 21.999 221.883 -2.188 1.00 27.71 ? 352 CYS A N 1 ATOM 701 C CA . CYS A 1 46 ? 23.076 221.155 -2.836 1.00 28.54 ? 352 CYS A CA 1 ATOM 702 C C . CYS A 1 46 ? 22.526 220.445 -4.066 1.00 24.08 ? 352 CYS A C 1 ATOM 703 O O . CYS A 1 46 ? 21.314 220.307 -4.239 1.00 26.67 ? 352 CYS A O 1 ATOM 704 C CB . CYS A 1 46 ? 23.728 220.169 -1.859 1.00 26.28 ? 352 CYS A CB 1 ATOM 705 S SG . CYS A 1 46 ? 22.605 218.931 -1.215 1.00 34.17 ? 352 CYS A SG 1 ATOM 706 H H . CYS A 1 46 ? 21.211 221.644 -2.436 1.00 33.26 ? 352 CYS A H 1 ATOM 707 H HA . CYS A 1 46 ? 23.755 221.783 -3.128 1.00 34.25 ? 352 CYS A HA 1 ATOM 708 H HB2 . CYS A 1 46 ? 24.447 219.706 -2.317 1.00 31.54 ? 352 CYS A HB2 1 ATOM 709 H HB3 . CYS A 1 46 ? 24.084 220.665 -1.106 1.00 31.54 ? 352 CYS A HB3 1 ATOM 710 N N . ASN A 1 47 ? 23.428 220.007 -4.925 1.00 21.89 ? 353 ASN A N 1 ATOM 711 C CA . ASN A 1 47 ? 23.040 219.367 -6.172 1.00 27.74 ? 353 ASN A CA 1 ATOM 712 C C . ASN A 1 47 ? 23.298 217.876 -6.089 1.00 28.11 ? 353 ASN A C 1 ATOM 713 O O . ASN A 1 47 ? 24.363 217.445 -5.636 1.00 29.44 ? 353 ASN A O 1 ATOM 714 C CB . ASN A 1 47 ? 23.802 219.945 -7.359 1.00 29.25 ? 353 ASN A CB 1 ATOM 715 C CG . ASN A 1 47 ? 23.654 221.453 -7.452 1.00 38.51 ? 353 ASN A CG 1 ATOM 716 O OD1 . ASN A 1 47 ? 24.639 222.177 -7.545 1.00 40.50 ? 353 ASN A OD1 1 ATOM 717 N ND2 . ASN A 1 47 ? 22.419 221.932 -7.386 1.00 28.87 ? 353 ASN A ND2 1 ATOM 718 H H . ASN A 1 47 ? 24.278 220.068 -4.810 1.00 26.27 ? 353 ASN A H 1 ATOM 719 H HA . ASN A 1 47 ? 22.092 219.505 -6.321 1.00 33.29 ? 353 ASN A HA 1 ATOM 720 H HB2 . ASN A 1 47 ? 24.745 219.740 -7.263 1.00 35.10 ? 353 ASN A HB2 1 ATOM 721 H HB3 . ASN A 1 47 ? 23.457 219.557 -8.178 1.00 35.10 ? 353 ASN A HB3 1 ATOM 722 H HD21 . ASN A 1 47 ? 22.283 222.780 -7.434 1.00 34.65 ? 353 ASN A HD21 1 ATOM 723 H HD22 . ASN A 1 47 ? 21.754 221.394 -7.294 1.00 34.65 ? 353 ASN A HD22 1 ATOM 724 N N . PHE A 1 48 ? 22.320 217.100 -6.533 1.00 24.51 ? 354 PHE A N 1 ATOM 725 C CA . PHE A 1 48 ? 22.437 215.654 -6.572 1.00 28.59 ? 354 PHE A CA 1 ATOM 726 C C . PHE A 1 48 ? 22.153 215.148 -7.977 1.00 27.10 ? 354 PHE A C 1 ATOM 727 O O . PHE A 1 48 ? 21.513 215.816 -8.789 1.00 27.94 ? 354 PHE A O 1 ATOM 728 C CB . PHE A 1 48 ? 21.486 214.980 -5.567 1.00 20.73 ? 354 PHE A CB 1 ATOM 729 C CG . PHE A 1 48 ? 20.032 215.151 -5.893 1.00 18.10 ? 354 PHE A CG 1 ATOM 730 C CD1 . PHE A 1 48 ? 19.362 216.310 -5.554 1.00 24.82 ? 354 PHE A CD1 1 ATOM 731 C CD2 . PHE A 1 48 ? 19.337 214.148 -6.546 1.00 19.89 ? 354 PHE A CD2 1 ATOM 732 C CE1 . PHE A 1 48 ? 18.022 216.472 -5.866 1.00 24.96 ? 354 PHE A CE1 1 ATOM 733 C CE2 . PHE A 1 48 ? 18.001 214.298 -6.855 1.00 19.85 ? 354 PHE A CE2 1 ATOM 734 C CZ . PHE A 1 48 ? 17.342 215.451 -6.519 1.00 28.78 ? 354 PHE A CZ 1 ATOM 735 H H . PHE A 1 48 ? 21.565 217.394 -6.823 1.00 29.41 ? 354 PHE A H 1 ATOM 736 H HA . PHE A 1 48 ? 23.346 215.404 -6.340 1.00 34.31 ? 354 PHE A HA 1 ATOM 737 H HB2 . PHE A 1 48 ? 21.676 214.029 -5.548 1.00 24.88 ? 354 PHE A HB2 1 ATOM 738 H HB3 . PHE A 1 48 ? 21.639 215.362 -4.688 1.00 24.88 ? 354 PHE A HB3 1 ATOM 739 H HD1 . PHE A 1 48 ? 19.818 216.993 -5.119 1.00 29.78 ? 354 PHE A HD1 1 ATOM 740 H HD2 . PHE A 1 48 ? 19.776 213.362 -6.779 1.00 23.87 ? 354 PHE A HD2 1 ATOM 741 H HE1 . PHE A 1 48 ? 17.579 217.256 -5.633 1.00 29.95 ? 354 PHE A HE1 1 ATOM 742 H HE2 . PHE A 1 48 ? 17.547 213.615 -7.293 1.00 23.82 ? 354 PHE A HE2 1 ATOM 743 H HZ . PHE A 1 48 ? 16.442 215.550 -6.727 1.00 34.53 ? 354 PHE A HZ 1 ATOM 744 N N . ASN A 1 49 ? 22.638 213.942 -8.233 1.00 25.29 ? 355 ASN A N 1 ATOM 745 C CA . ASN A 1 49 ? 22.454 213.222 -9.496 1.00 28.84 ? 355 ASN A CA 1 ATOM 746 C C . ASN A 1 49 ? 21.872 211.843 -9.176 1.00 23.98 ? 355 ASN A C 1 ATOM 747 O O . ASN A 1 49 ? 22.595 210.951 -8.727 1.00 23.42 ? 355 ASN A O 1 ATOM 748 C CB . ASN A 1 49 ? 23.788 213.092 -10.217 1.00 34.27 ? 355 ASN A CB 1 ATOM 749 C CG . ASN A 1 49 ? 23.908 213.951 -11.431 1.00 48.82 ? 355 ASN A CG 1 ATOM 750 O OD1 . ASN A 1 49 ? 23.341 215.045 -11.510 1.00 48.30 ? 355 ASN A OD1 1 ATOM 751 N ND2 . ASN A 1 49 ? 24.682 213.452 -12.404 1.00 51.18 ? 355 ASN A ND2 1 ATOM 752 H H . ASN A 1 49 ? 23.102 213.496 -7.663 1.00 30.35 ? 355 ASN A H 1 ATOM 753 H HA . ASN A 1 49 ? 21.833 213.703 -10.065 1.00 34.61 ? 355 ASN A HA 1 ATOM 754 H HB2 . ASN A 1 49 ? 24.498 213.343 -9.607 1.00 41.12 ? 355 ASN A HB2 1 ATOM 755 H HB3 . ASN A 1 49 ? 23.904 212.170 -10.495 1.00 41.12 ? 355 ASN A HB3 1 ATOM 756 H HD21 . ASN A 1 49 ? 25.062 212.691 -12.278 1.00 61.41 ? 355 ASN A HD21 1 ATOM 757 N N . LEU A 1 50 ? 20.570 211.667 -9.391 1.00 24.02 ? 356 LEU A N 1 ATOM 758 C CA . LEU A 1 50 ? 19.948 210.374 -9.123 1.00 25.24 ? 356 LEU A CA 1 ATOM 759 C C . LEU A 1 50 ? 20.517 209.275 -10.013 1.00 29.49 ? 356 LEU A C 1 ATOM 760 O O . LEU A 1 50 ? 20.726 208.148 -9.551 1.00 23.25 ? 356 LEU A O 1 ATOM 761 C CB . LEU A 1 50 ? 18.430 210.447 -9.306 1.00 29.33 ? 356 LEU A CB 1 ATOM 762 C CG . LEU A 1 50 ? 17.662 209.131 -9.077 1.00 26.52 ? 356 LEU A CG 1 ATOM 763 C CD1 . LEU A 1 50 ? 17.903 208.589 -7.654 1.00 26.03 ? 356 LEU A CD1 1 ATOM 764 C CD2 . LEU A 1 50 ? 16.169 209.328 -9.303 1.00 29.68 ? 356 LEU A CD2 1 ATOM 765 H H . LEU A 1 50 ? 20.033 212.270 -9.687 1.00 28.82 ? 356 LEU A H 1 ATOM 766 H HA . LEU A 1 50 ? 20.124 210.129 -8.201 1.00 30.29 ? 356 LEU A HA 1 ATOM 767 H HB2 . LEU A 1 50 ? 18.078 211.100 -8.681 1.00 35.20 ? 356 LEU A HB2 1 ATOM 768 H HB3 . LEU A 1 50 ? 18.246 210.736 -10.213 1.00 35.20 ? 356 LEU A HB3 1 ATOM 769 H HG . LEU A 1 50 ? 17.977 208.467 -9.710 1.00 31.83 ? 356 LEU A HG 1 ATOM 770 H HD11 . LEU A 1 50 ? 17.407 207.763 -7.543 1.00 31.24 ? 356 LEU A HD11 1 ATOM 771 H HD12 . LEU A 1 50 ? 18.851 208.424 -7.536 1.00 31.24 ? 356 LEU A HD12 1 ATOM 772 H HD13 . LEU A 1 50 ? 17.598 209.247 -7.010 1.00 31.24 ? 356 LEU A HD13 1 ATOM 773 H HD21 . LEU A 1 50 ? 15.713 208.485 -9.152 1.00 35.62 ? 356 LEU A HD21 1 ATOM 774 H HD22 . LEU A 1 50 ? 15.841 209.998 -8.682 1.00 35.62 ? 356 LEU A HD22 1 ATOM 775 H HD23 . LEU A 1 50 ? 16.024 209.624 -10.215 1.00 35.62 ? 356 LEU A HD23 1 ATOM 776 N N . SER A 1 51 ? 20.746 209.559 -11.300 1.00 28.99 ? 357 SER A N 1 ATOM 777 C CA . SER A 1 51 ? 21.253 208.503 -12.174 1.00 25.29 ? 357 SER A CA 1 ATOM 778 C C . SER A 1 51 ? 22.644 208.063 -11.732 1.00 27.78 ? 357 SER A C 1 ATOM 779 O O . SER A 1 51 ? 22.933 206.864 -11.649 1.00 29.98 ? 357 SER A O 1 ATOM 780 C CB . SER A 1 51 ? 21.244 208.953 -13.637 1.00 26.67 ? 357 SER A CB 1 ATOM 781 O OG . SER A 1 51 ? 22.044 210.075 -13.864 1.00 30.39 ? 357 SER A OG 1 ATOM 782 H H . SER A 1 51 ? 20.621 210.322 -11.677 1.00 34.79 ? 357 SER A H 1 ATOM 783 H HA . SER A 1 51 ? 20.667 207.734 -12.101 1.00 30.34 ? 357 SER A HA 1 ATOM 784 H HB2 . SER A 1 51 ? 21.571 208.224 -14.187 1.00 32.01 ? 357 SER A HB2 1 ATOM 785 H HB3 . SER A 1 51 ? 20.332 209.167 -13.888 1.00 32.01 ? 357 SER A HB3 1 ATOM 786 H HG . SER A 1 51 ? 21.772 210.720 -13.400 1.00 36.47 ? 357 SER A HG 1 ATOM 787 N N . THR A 1 52 ? 23.504 209.015 -11.388 1.00 29.80 ? 358 THR A N 1 ATOM 788 C CA . THR A 1 52 ? 24.814 208.660 -10.858 1.00 31.05 ? 358 THR A CA 1 ATOM 789 C C . THR A 1 52 ? 24.673 207.882 -9.556 1.00 30.82 ? 358 THR A C 1 ATOM 790 O O . THR A 1 52 ? 25.384 206.896 -9.322 1.00 26.01 ? 358 THR A O 1 ATOM 791 C CB . THR A 1 52 ? 25.638 209.927 -10.627 1.00 30.20 ? 358 THR A CB 1 ATOM 792 O OG1 . THR A 1 52 ? 25.535 210.791 -11.766 1.00 45.35 ? 358 THR A OG1 1 ATOM 793 C CG2 . THR A 1 52 ? 27.084 209.587 -10.404 1.00 36.86 ? 358 THR A CG2 1 ATOM 794 H H . THR A 1 52 ? 23.358 209.860 -11.451 1.00 35.76 ? 358 THR A H 1 ATOM 795 H HA . THR A 1 52 ? 25.282 208.103 -11.499 1.00 37.26 ? 358 THR A HA 1 ATOM 796 H HB . THR A 1 52 ? 25.306 210.389 -9.841 1.00 36.24 ? 358 THR A HB 1 ATOM 797 H HG1 . THR A 1 52 ? 25.988 211.487 -11.640 1.00 54.42 ? 358 THR A HG1 1 ATOM 798 H HG21 . THR A 1 52 ? 27.596 210.398 -10.258 1.00 44.23 ? 358 THR A HG21 1 ATOM 799 H HG22 . THR A 1 52 ? 27.173 209.014 -9.626 1.00 44.23 ? 358 THR A HG22 1 ATOM 800 H HG23 . THR A 1 52 ? 27.438 209.124 -11.179 1.00 44.23 ? 358 THR A HG23 1 ATOM 801 N N . LEU A 1 53 ? 23.736 208.299 -8.710 1.00 26.99 ? 359 LEU A N 1 ATOM 802 C CA . LEU A 1 53 ? 23.549 207.651 -7.420 1.00 28.31 ? 359 LEU A CA 1 ATOM 803 C C . LEU A 1 53 ? 23.245 206.165 -7.593 1.00 24.62 ? 359 LEU A C 1 ATOM 804 O O . LEU A 1 53 ? 23.897 205.310 -6.988 1.00 24.81 ? 359 LEU A O 1 ATOM 805 C CB . LEU A 1 53 ? 22.424 208.358 -6.664 1.00 24.79 ? 359 LEU A CB 1 ATOM 806 C CG . LEU A 1 53 ? 22.146 207.866 -5.245 1.00 28.82 ? 359 LEU A CG 1 ATOM 807 C CD1 . LEU A 1 53 ? 23.359 208.110 -4.381 1.00 32.80 ? 359 LEU A CD1 1 ATOM 808 C CD2 . LEU A 1 53 ? 20.937 208.574 -4.633 1.00 33.40 ? 359 LEU A CD2 1 ATOM 809 H H . LEU A 1 53 ? 23.197 208.953 -8.859 1.00 32.39 ? 359 LEU A H 1 ATOM 810 H HA . LEU A 1 53 ? 24.364 207.735 -6.899 1.00 33.97 ? 359 LEU A HA 1 ATOM 811 H HB2 . LEU A 1 53 ? 22.644 209.301 -6.604 1.00 29.75 ? 359 LEU A HB2 1 ATOM 812 H HB3 . LEU A 1 53 ? 21.604 208.251 -7.171 1.00 29.75 ? 359 LEU A HB3 1 ATOM 813 H HG . LEU A 1 53 ? 21.968 206.913 -5.262 1.00 34.59 ? 359 LEU A HG 1 ATOM 814 H HD11 . LEU A 1 53 ? 23.175 207.796 -3.482 1.00 39.36 ? 359 LEU A HD11 1 ATOM 815 H HD12 . LEU A 1 53 ? 24.114 207.627 -4.753 1.00 39.36 ? 359 LEU A HD12 1 ATOM 816 H HD13 . LEU A 1 53 ? 23.550 209.061 -4.367 1.00 39.36 ? 359 LEU A HD13 1 ATOM 817 H HD21 . LEU A 1 53 ? 20.794 208.235 -3.736 1.00 40.08 ? 359 LEU A HD21 1 ATOM 818 H HD22 . LEU A 1 53 ? 21.111 209.527 -4.603 1.00 40.08 ? 359 LEU A HD22 1 ATOM 819 H HD23 . LEU A 1 53 ? 20.157 208.396 -5.182 1.00 40.08 ? 359 LEU A HD23 1 ATOM 820 N N . LEU A 1 54 ? 22.256 205.845 -8.428 1.00 22.01 ? 360 LEU A N 1 ATOM 821 C CA . LEU A 1 54 ? 21.854 204.466 -8.640 1.00 33.21 ? 360 LEU A CA 1 ATOM 822 C C . LEU A 1 54 ? 22.983 203.610 -9.201 1.00 29.34 ? 360 LEU A C 1 ATOM 823 O O . LEU A 1 54 ? 22.979 202.403 -8.981 1.00 30.73 ? 360 LEU A O 1 ATOM 824 C CB . LEU A 1 54 ? 20.643 204.411 -9.572 1.00 26.99 ? 360 LEU A CB 1 ATOM 825 C CG . LEU A 1 54 ? 19.368 205.130 -9.122 1.00 28.37 ? 360 LEU A CG 1 ATOM 826 C CD1 . LEU A 1 54 ? 18.305 205.022 -10.218 1.00 33.76 ? 360 LEU A CD1 1 ATOM 827 C CD2 . LEU A 1 54 ? 18.844 204.585 -7.798 1.00 30.48 ? 360 LEU A CD2 1 ATOM 828 H H . LEU A 1 54 ? 21.802 206.416 -8.884 1.00 26.41 ? 360 LEU A H 1 ATOM 829 H HA . LEU A 1 54 ? 21.589 204.084 -7.789 1.00 39.85 ? 360 LEU A HA 1 ATOM 830 H HB2 . LEU A 1 54 ? 20.902 204.800 -10.423 1.00 32.38 ? 360 LEU A HB2 1 ATOM 831 H HB3 . LEU A 1 54 ? 20.411 203.479 -9.707 1.00 32.38 ? 360 LEU A HB3 1 ATOM 832 H HG . LEU A 1 54 ? 19.568 206.071 -8.996 1.00 34.04 ? 360 LEU A HG 1 ATOM 833 H HD11 . LEU A 1 54 ? 17.501 205.480 -9.924 1.00 40.52 ? 360 LEU A HD11 1 ATOM 834 H HD12 . LEU A 1 54 ? 18.644 205.434 -11.027 1.00 40.52 ? 360 LEU A HD12 1 ATOM 835 H HD13 . LEU A 1 54 ? 18.112 204.085 -10.378 1.00 40.52 ? 360 LEU A HD13 1 ATOM 836 H HD21 . LEU A 1 54 ? 18.039 205.068 -7.553 1.00 36.57 ? 360 LEU A HD21 1 ATOM 837 H HD22 . LEU A 1 54 ? 18.645 203.641 -7.902 1.00 36.57 ? 360 LEU A HD22 1 ATOM 838 H HD23 . LEU A 1 54 ? 19.523 204.706 -7.116 1.00 36.57 ? 360 LEU A HD23 1 ATOM 839 N N . ARG A 1 55 ? 23.959 204.195 -9.892 1.00 29.86 ? 361 ARG A N 1 ATOM 840 C CA . ARG A 1 55 ? 25.093 203.416 -10.381 1.00 29.04 ? 361 ARG A CA 1 ATOM 841 C C . ARG A 1 55 ? 26.187 203.237 -9.334 1.00 32.13 ? 361 ARG A C 1 ATOM 842 O O . ARG A 1 55 ? 26.843 202.193 -9.314 1.00 42.97 ? 361 ARG A O 1 ATOM 843 C CB . ARG A 1 55 ? 25.709 204.080 -11.614 1.00 34.21 ? 361 ARG A CB 1 ATOM 844 C CG . ARG A 1 55 ? 24.772 204.216 -12.811 1.00 40.17 ? 361 ARG A CG 1 ATOM 845 C CD . ARG A 1 55 ? 25.494 204.825 -14.043 1.00 45.94 ? 361 ARG A CD 1 ATOM 846 N NE . ARG A 1 55 ? 26.431 205.890 -13.670 1.00 60.38 ? 361 ARG A NE 1 ATOM 847 C CZ . ARG A 1 55 ? 27.737 205.716 -13.459 1.00 68.80 ? 361 ARG A CZ 1 ATOM 848 N NH1 . ARG A 1 55 ? 28.295 204.515 -13.595 1.00 71.34 ? 361 ARG A NH1 1 ATOM 849 N NH2 . ARG A 1 55 ? 28.497 206.749 -13.111 1.00 49.69 ? 361 ARG A NH2 1 ATOM 850 H H . ARG A 1 55 ? 23.989 205.032 -10.089 1.00 35.84 ? 361 ARG A H 1 ATOM 851 H HA . ARG A 1 55 ? 24.780 202.535 -10.640 1.00 34.85 ? 361 ARG A HA 1 ATOM 852 H HB2 . ARG A 1 55 ? 26.003 204.971 -11.370 1.00 41.05 ? 361 ARG A HB2 1 ATOM 853 H HB3 . ARG A 1 55 ? 26.472 203.552 -11.898 1.00 41.05 ? 361 ARG A HB3 1 ATOM 854 H HG2 . ARG A 1 55 ? 24.440 203.338 -13.058 1.00 48.21 ? 361 ARG A HG2 1 ATOM 855 H HG3 . ARG A 1 55 ? 24.034 204.798 -12.573 1.00 48.21 ? 361 ARG A HG3 1 ATOM 856 H HD2 . ARG A 1 55 ? 25.995 204.128 -14.494 1.00 55.13 ? 361 ARG A HD2 1 ATOM 857 H HD3 . ARG A 1 55 ? 24.833 205.202 -14.644 1.00 55.13 ? 361 ARG A HD3 1 ATOM 858 H HE . ARG A 1 55 ? 26.115 206.685 -13.581 1.00 72.45 ? 361 ARG A HE 1 ATOM 859 H HH11 . ARG A 1 55 ? 27.812 203.839 -13.817 1.00 85.61 ? 361 ARG A HH11 1 ATOM 860 H HH12 . ARG A 1 55 ? 29.139 204.414 -13.459 1.00 85.61 ? 361 ARG A HH12 1 ATOM 861 H HH21 . ARG A 1 55 ? 28.146 207.530 -13.024 1.00 59.63 ? 361 ARG A HH21 1 ATOM 862 H HH22 . ARG A 1 55 ? 29.339 206.639 -12.981 1.00 59.63 ? 361 ARG A HH22 1 ATOM 863 N N . LEU A 1 56 ? 26.418 204.230 -8.476 1.00 32.58 ? 362 LEU A N 1 ATOM 864 C CA . LEU A 1 56 ? 27.533 204.166 -7.538 1.00 33.50 ? 362 LEU A CA 1 ATOM 865 C C . LEU A 1 56 ? 27.211 203.365 -6.285 1.00 30.40 ? 362 LEU A C 1 ATOM 866 O O . LEU A 1 56 ? 28.131 202.882 -5.612 1.00 27.95 ? 362 LEU A O 1 ATOM 867 C CB . LEU A 1 56 ? 27.964 205.580 -7.144 1.00 36.03 ? 362 LEU A CB 1 ATOM 868 C CG . LEU A 1 56 ? 28.579 206.412 -8.272 1.00 39.12 ? 362 LEU A CG 1 ATOM 869 C CD1 . LEU A 1 56 ? 28.956 207.767 -7.745 1.00 38.56 ? 362 LEU A CD1 1 ATOM 870 C CD2 . LEU A 1 56 ? 29.793 205.725 -8.901 1.00 35.23 ? 362 LEU A CD2 1 ATOM 871 H H . LEU A 1 56 ? 25.946 204.946 -8.418 1.00 39.10 ? 362 LEU A H 1 ATOM 872 H HA . LEU A 1 56 ? 28.285 203.739 -7.977 1.00 40.19 ? 362 LEU A HA 1 ATOM 873 H HB2 . LEU A 1 56 ? 27.186 206.059 -6.819 1.00 43.23 ? 362 LEU A HB2 1 ATOM 874 H HB3 . LEU A 1 56 ? 28.624 205.515 -6.436 1.00 43.23 ? 362 LEU A HB3 1 ATOM 875 H HG . LEU A 1 56 ? 27.915 206.537 -8.967 1.00 46.95 ? 362 LEU A HG 1 ATOM 876 H HD11 . LEU A 1 56 ? 29.345 208.288 -8.465 1.00 46.27 ? 362 LEU A HD11 1 ATOM 877 H HD12 . LEU A 1 56 ? 28.159 208.208 -7.410 1.00 46.27 ? 362 LEU A HD12 1 ATOM 878 H HD13 . LEU A 1 56 ? 29.601 207.659 -7.029 1.00 46.27 ? 362 LEU A HD13 1 ATOM 879 H HD21 . LEU A 1 56 ? 30.144 206.290 -9.606 1.00 42.27 ? 362 LEU A HD21 1 ATOM 880 H HD22 . LEU A 1 56 ? 30.468 205.589 -8.217 1.00 42.27 ? 362 LEU A HD22 1 ATOM 881 H HD23 . LEU A 1 56 ? 29.516 204.870 -9.267 1.00 42.27 ? 362 LEU A HD23 1 ATOM 882 N N . VAL A 1 57 ? 25.944 203.223 -5.942 1.00 22.27 ? 363 VAL A N 1 ATOM 883 C CA . VAL A 1 57 ? 25.533 202.268 -4.933 1.00 30.77 ? 363 VAL A CA 1 ATOM 884 C C . VAL A 1 57 ? 24.979 201.042 -5.658 1.00 31.61 ? 363 VAL A C 1 ATOM 885 O O . VAL A 1 57 ? 24.120 201.160 -6.542 1.00 31.19 ? 363 VAL A O 1 ATOM 886 C CB . VAL A 1 57 ? 24.525 202.900 -3.951 1.00 33.31 ? 363 VAL A CB 1 ATOM 887 C CG1 . VAL A 1 57 ? 24.856 204.398 -3.726 1.00 25.96 ? 363 VAL A CG1 1 ATOM 888 C CG2 . VAL A 1 57 ? 23.113 202.740 -4.410 1.00 27.47 ? 363 VAL A CG2 1 ATOM 889 H H . VAL A 1 57 ? 25.296 203.674 -6.283 1.00 26.72 ? 363 VAL A H 1 ATOM 890 H HA . VAL A 1 57 ? 26.312 201.990 -4.425 1.00 36.92 ? 363 VAL A HA 1 ATOM 891 H HB . VAL A 1 57 ? 24.607 202.451 -3.094 1.00 39.98 ? 363 VAL A HB 1 ATOM 892 H HG11 . VAL A 1 57 ? 24.211 204.774 -3.107 1.00 31.15 ? 363 VAL A HG11 1 ATOM 893 H HG12 . VAL A 1 57 ? 25.750 204.472 -3.359 1.00 31.15 ? 363 VAL A HG12 1 ATOM 894 H HG13 . VAL A 1 57 ? 24.807 204.862 -4.577 1.00 31.15 ? 363 VAL A HG13 1 ATOM 895 H HG21 . VAL A 1 57 ? 22.522 203.152 -3.761 1.00 32.97 ? 363 VAL A HG21 1 ATOM 896 H HG22 . VAL A 1 57 ? 23.011 203.173 -5.273 1.00 32.97 ? 363 VAL A HG22 1 ATOM 897 H HG23 . VAL A 1 57 ? 22.912 201.794 -4.489 1.00 32.97 ? 363 VAL A HG23 1 ATOM 898 N N . HIS A 1 58 ? 25.522 199.873 -5.337 1.00 32.01 ? 364 HIS A N 1 ATOM 899 C CA . HIS A 1 58 ? 25.143 198.618 -5.981 1.00 23.99 ? 364 HIS A CA 1 ATOM 900 C C . HIS A 1 58 ? 23.643 198.400 -5.789 1.00 24.75 ? 364 HIS A C 1 ATOM 901 O O . HIS A 1 58 ? 23.219 197.656 -4.900 1.00 23.16 ? 364 HIS A O 1 ATOM 902 C CB . HIS A 1 58 ? 26.012 197.520 -5.377 1.00 27.24 ? 364 HIS A CB 1 ATOM 903 C CG . HIS A 1 58 ? 25.859 196.164 -5.987 1.00 38.28 ? 364 HIS A CG 1 ATOM 904 N ND1 . HIS A 1 58 ? 24.665 195.474 -6.004 1.00 44.53 ? 364 HIS A ND1 1 ATOM 905 C CD2 . HIS A 1 58 ? 26.784 195.326 -6.510 1.00 36.22 ? 364 HIS A CD2 1 ATOM 906 C CE1 . HIS A 1 58 ? 24.854 194.287 -6.553 1.00 44.48 ? 364 HIS A CE1 1 ATOM 907 N NE2 . HIS A 1 58 ? 26.131 194.173 -6.869 1.00 39.64 ? 364 HIS A NE2 1 ATOM 908 H H . HIS A 1 58 ? 26.127 199.778 -4.733 1.00 38.41 ? 364 HIS A H 1 ATOM 909 H HA . HIS A 1 58 ? 25.328 198.671 -6.932 1.00 28.79 ? 364 HIS A HA 1 ATOM 910 H HB2 . HIS A 1 58 ? 26.942 197.778 -5.473 1.00 32.69 ? 364 HIS A HB2 1 ATOM 911 H HB3 . HIS A 1 58 ? 25.794 197.440 -4.435 1.00 32.69 ? 364 HIS A HB3 1 ATOM 912 H HD2 . HIS A 1 58 ? 27.690 195.505 -6.623 1.00 43.47 ? 364 HIS A HD2 1 ATOM 913 H HE1 . HIS A 1 58 ? 24.198 193.643 -6.697 1.00 53.38 ? 364 HIS A HE1 1 ATOM 914 H HE2 . HIS A 1 58 ? 26.494 193.490 -7.244 1.00 47.56 ? 364 HIS A HE2 1 ATOM 915 N N . THR A 1 59 ? 22.832 199.103 -6.580 1.00 21.79 ? 365 THR A N 1 ATOM 916 C CA . THR A 1 59 ? 21.388 199.123 -6.376 1.00 22.71 ? 365 THR A CA 1 ATOM 917 C C . THR A 1 59 ? 20.739 197.820 -6.820 1.00 23.59 ? 365 THR A C 1 ATOM 918 O O . THR A 1 59 ? 21.009 197.321 -7.915 1.00 25.48 ? 365 THR A O 1 ATOM 919 C CB . THR A 1 59 ? 20.773 200.292 -7.150 1.00 20.85 ? 365 THR A CB 1 ATOM 920 O OG1 . THR A 1 59 ? 21.225 201.522 -6.583 1.00 25.19 ? 365 THR A OG1 1 ATOM 921 C CG2 . THR A 1 59 ? 19.249 200.264 -7.111 1.00 19.41 ? 365 THR A CG2 1 ATOM 922 H H . THR A 1 59 ? 23.097 199.579 -7.246 1.00 26.15 ? 365 THR A H 1 ATOM 923 H HA . THR A 1 59 ? 21.200 199.250 -5.433 1.00 27.25 ? 365 THR A HA 1 ATOM 924 H HB . THR A 1 59 ? 21.054 200.245 -8.077 1.00 25.02 ? 365 THR A HB 1 ATOM 925 H HG1 . THR A 1 59 ? 22.063 201.569 -6.628 1.00 30.23 ? 365 THR A HG1 1 ATOM 926 H HG21 . THR A 1 59 ? 18.891 201.015 -7.609 1.00 23.29 ? 365 THR A HG21 1 ATOM 927 H HG22 . THR A 1 59 ? 18.923 199.440 -7.506 1.00 23.29 ? 365 THR A HG22 1 ATOM 928 H HG23 . THR A 1 59 ? 18.940 200.318 -6.193 1.00 23.29 ? 365 THR A HG23 1 ATOM 929 N N A ASP A 1 60 ? 19.866 197.279 -5.974 0.68 22.82 ? 366 ASP A N 1 ATOM 930 N N B ASP A 1 60 ? 19.882 197.267 -5.961 0.32 23.04 ? 366 ASP A N 1 ATOM 931 C CA A ASP A 1 60 ? 19.036 196.148 -6.357 0.68 22.60 ? 366 ASP A CA 1 ATOM 932 C CA B ASP A 1 60 ? 19.037 196.134 -6.312 0.32 22.84 ? 366 ASP A CA 1 ATOM 933 C C A ASP A 1 60 ? 17.634 196.573 -6.771 0.68 23.52 ? 366 ASP A C 1 ATOM 934 C C B ASP A 1 60 ? 17.645 196.563 -6.756 0.32 23.67 ? 366 ASP A C 1 ATOM 935 O O A ASP A 1 60 ? 17.103 196.063 -7.762 0.68 25.50 ? 366 ASP A O 1 ATOM 936 O O B ASP A 1 60 ? 17.128 196.038 -7.747 0.32 25.48 ? 366 ASP A O 1 ATOM 937 C CB A ASP A 1 60 ? 18.954 195.126 -5.216 0.68 25.18 ? 366 ASP A CB 1 ATOM 938 C CB B ASP A 1 60 ? 18.919 195.160 -5.131 0.32 25.17 ? 366 ASP A CB 1 ATOM 939 C CG A ASP A 1 60 ? 18.225 193.850 -5.623 0.68 27.50 ? 366 ASP A CG 1 ATOM 940 C CG B ASP A 1 60 ? 20.054 194.138 -5.083 0.32 27.78 ? 366 ASP A CG 1 ATOM 941 O OD1 A ASP A 1 60 ? 18.777 193.057 -6.425 0.68 31.88 ? 366 ASP A OD1 1 ATOM 942 O OD1 B ASP A 1 60 ? 20.488 193.642 -6.145 0.32 27.30 ? 366 ASP A OD1 1 ATOM 943 O OD2 A ASP A 1 60 ? 17.089 193.649 -5.145 0.68 25.67 ? 366 ASP A OD2 1 ATOM 944 O OD2 B ASP A 1 60 ? 20.508 193.818 -3.964 0.32 31.44 ? 366 ASP A OD2 1 ATOM 945 H HA A ASP A 1 60 ? 19.445 195.708 -7.118 0.68 27.12 ? 366 ASP A HA 1 ATOM 946 H HA B ASP A 1 60 ? 19.448 195.656 -7.049 0.32 27.41 ? 366 ASP A HA 1 ATOM 947 H HB2 A ASP A 1 60 ? 19.853 194.884 -4.943 0.68 30.22 ? 366 ASP A HB2 1 ATOM 948 H HB2 B ASP A 1 60 ? 18.937 195.665 -4.303 0.32 30.20 ? 366 ASP A HB2 1 ATOM 949 H HB3 A ASP A 1 60 ? 18.476 195.521 -4.470 0.68 30.22 ? 366 ASP A HB3 1 ATOM 950 H HB3 B ASP A 1 60 ? 18.082 194.675 -5.204 0.32 30.20 ? 366 ASP A HB3 1 ATOM 951 N N . SER A 1 61 ? 17.018 197.501 -6.051 1.00 18.26 ? 367 SER A N 1 ATOM 952 C CA . SER A 1 61 ? 15.752 198.047 -6.511 1.00 20.35 ? 367 SER A CA 1 ATOM 953 C C . SER A 1 61 ? 15.524 199.427 -5.908 1.00 22.49 ? 367 SER A C 1 ATOM 954 O O . SER A 1 61 ? 16.103 199.804 -4.880 1.00 20.92 ? 367 SER A O 1 ATOM 955 C CB . SER A 1 61 ? 14.577 197.125 -6.191 1.00 22.30 ? 367 SER A CB 1 ATOM 956 O OG . SER A 1 61 ? 14.271 197.129 -4.816 1.00 32.49 ? 367 SER A OG 1 ATOM 957 H HA . SER A 1 61 ? 15.791 198.149 -7.474 1.00 24.42 ? 367 SER A HA 1 ATOM 958 H HB2 . SER A 1 61 ? 13.799 197.427 -6.685 1.00 26.75 ? 367 SER A HB2 1 ATOM 959 H HB3 . SER A 1 61 ? 14.807 196.222 -6.457 1.00 26.75 ? 367 SER A HB3 1 ATOM 960 H HG . SER A 1 61 ? 13.624 196.617 -4.665 1.00 38.99 ? 367 SER A HG 1 ATOM 961 N N . PHE A 1 62 ? 14.631 200.157 -6.557 1.00 19.57 ? 368 PHE A N 1 ATOM 962 C CA . PHE A 1 62 ? 14.377 201.552 -6.236 1.00 17.84 ? 368 PHE A CA 1 ATOM 963 C C . PHE A 1 62 ? 12.998 201.879 -6.767 1.00 21.46 ? 368 PHE A C 1 ATOM 964 O O . PHE A 1 62 ? 12.725 201.662 -7.954 1.00 26.16 ? 368 PHE A O 1 ATOM 965 C CB . PHE A 1 62 ? 15.430 202.462 -6.842 1.00 19.45 ? 368 PHE A CB 1 ATOM 966 C CG . PHE A 1 62 ? 15.213 203.913 -6.535 1.00 21.93 ? 368 PHE A CG 1 ATOM 967 C CD1 . PHE A 1 62 ? 15.543 204.421 -5.290 1.00 21.89 ? 368 PHE A CD1 1 ATOM 968 C CD2 . PHE A 1 62 ? 14.659 204.775 -7.490 1.00 24.63 ? 368 PHE A CD2 1 ATOM 969 C CE1 . PHE A 1 62 ? 15.348 205.778 -4.986 1.00 22.61 ? 368 PHE A CE1 1 ATOM 970 C CE2 . PHE A 1 62 ? 14.453 206.137 -7.200 1.00 25.90 ? 368 PHE A CE2 1 ATOM 971 C CZ . PHE A 1 62 ? 14.800 206.638 -5.942 1.00 26.17 ? 368 PHE A CZ 1 ATOM 972 H H . PHE A 1 62 ? 14.146 199.859 -7.202 1.00 23.49 ? 368 PHE A H 1 ATOM 973 H HA . PHE A 1 62 ? 14.378 201.673 -5.274 1.00 21.41 ? 368 PHE A HA 1 ATOM 974 H HB2 . PHE A 1 62 ? 16.300 202.212 -6.492 1.00 23.34 ? 368 PHE A HB2 1 ATOM 975 H HB3 . PHE A 1 62 ? 15.419 202.357 -7.806 1.00 23.34 ? 368 PHE A HB3 1 ATOM 976 H HD1 . PHE A 1 62 ? 15.912 203.856 -4.649 1.00 26.27 ? 368 PHE A HD1 1 ATOM 977 H HD2 . PHE A 1 62 ? 14.431 204.444 -8.329 1.00 29.56 ? 368 PHE A HD2 1 ATOM 978 H HE1 . PHE A 1 62 ? 15.579 206.104 -4.146 1.00 27.13 ? 368 PHE A HE1 1 ATOM 979 H HE2 . PHE A 1 62 ? 14.088 206.702 -7.843 1.00 31.08 ? 368 PHE A HE2 1 ATOM 980 H HZ . PHE A 1 62 ? 14.666 207.536 -5.742 1.00 31.41 ? 368 PHE A HZ 1 ATOM 981 N N . SER A 1 63 ? 12.124 202.358 -5.888 1.00 18.32 ? 369 SER A N 1 ATOM 982 C CA . SER A 1 63 ? 10.773 202.724 -6.269 1.00 21.10 ? 369 SER A CA 1 ATOM 983 C C . SER A 1 63 ? 10.313 203.860 -5.373 1.00 20.62 ? 369 SER A C 1 ATOM 984 O O . SER A 1 63 ? 10.901 204.121 -4.318 1.00 23.79 ? 369 SER A O 1 ATOM 985 C CB . SER A 1 63 ? 9.822 201.530 -6.146 1.00 23.19 ? 369 SER A CB 1 ATOM 986 O OG . SER A 1 63 ? 9.522 201.253 -4.786 1.00 27.36 ? 369 SER A OG 1 ATOM 987 H H . SER A 1 63 ? 12.296 202.480 -5.054 1.00 21.98 ? 369 SER A H 1 ATOM 988 H HA . SER A 1 63 ? 10.765 203.033 -7.188 1.00 25.32 ? 369 SER A HA 1 ATOM 989 H HB2 . SER A 1 63 ? 8.998 201.735 -6.615 1.00 27.83 ? 369 SER A HB2 1 ATOM 990 H HB3 . SER A 1 63 ? 10.243 200.751 -6.541 1.00 27.83 ? 369 SER A HB3 1 ATOM 991 H HG . SER A 1 63 ? 10.228 201.074 -4.367 1.00 32.83 ? 369 SER A HG 1 ATOM 992 N N . CYS A 1 64 ? 9.222 204.500 -5.772 1.00 15.70 ? 370 CYS A N 1 ATOM 993 C CA . CYS A 1 64 ? 8.719 205.662 -5.065 1.00 21.11 ? 370 CYS A CA 1 ATOM 994 C C . CYS A 1 64 ? 7.245 205.472 -4.759 1.00 19.27 ? 370 CYS A C 1 ATOM 995 O O . CYS A 1 64 ? 6.536 204.746 -5.446 1.00 18.85 ? 370 CYS A O 1 ATOM 996 C CB . CYS A 1 64 ? 8.959 206.943 -5.865 1.00 22.44 ? 370 CYS A CB 1 ATOM 997 S SG . CYS A 1 64 ? 10.713 207.249 -6.140 1.00 23.67 ? 370 CYS A SG 1 ATOM 998 H H . CYS A 1 64 ? 8.752 204.277 -6.457 1.00 18.84 ? 370 CYS A H 1 ATOM 999 H HA . CYS A 1 64 ? 9.191 205.745 -4.222 1.00 25.34 ? 370 CYS A HA 1 ATOM 1000 H HB2 . CYS A 1 64 ? 8.526 206.865 -6.730 1.00 26.93 ? 370 CYS A HB2 1 ATOM 1001 H HB3 . CYS A 1 64 ? 8.593 207.697 -5.376 1.00 26.93 ? 370 CYS A HB3 1 ATOM 1002 N N . ASN A 1 65 ? 6.813 206.107 -3.684 1.00 22.79 ? 371 ASN A N 1 ATOM 1003 C CA . ASN A 1 65 ? 5.445 206.040 -3.211 1.00 25.53 ? 371 ASN A CA 1 ATOM 1004 C C . ASN A 1 65 ? 4.913 207.461 -3.083 1.00 19.90 ? 371 ASN A C 1 ATOM 1005 O O . ASN A 1 65 ? 5.597 208.338 -2.552 1.00 23.29 ? 371 ASN A O 1 ATOM 1006 C CB . ASN A 1 65 ? 5.395 205.301 -1.865 1.00 21.15 ? 371 ASN A CB 1 ATOM 1007 C CG . ASN A 1 65 ? 3.999 205.172 -1.324 1.00 22.02 ? 371 ASN A CG 1 ATOM 1008 O OD1 . ASN A 1 65 ? 3.139 204.542 -1.936 1.00 21.23 ? 371 ASN A OD1 1 ATOM 1009 N ND2 . ASN A 1 65 ? 3.768 205.741 -0.147 1.00 26.92 ? 371 ASN A ND2 1 ATOM 1010 H H . ASN A 1 65 ? 7.315 206.603 -3.193 1.00 27.34 ? 371 ASN A H 1 ATOM 1011 H HA . ASN A 1 65 ? 4.899 205.558 -3.852 1.00 30.63 ? 371 ASN A HA 1 ATOM 1012 H HB2 . ASN A 1 65 ? 5.756 204.408 -1.980 1.00 25.38 ? 371 ASN A HB2 1 ATOM 1013 H HB3 . ASN A 1 65 ? 5.924 205.791 -1.215 1.00 25.38 ? 371 ASN A HB3 1 ATOM 1014 H HD21 . ASN A 1 65 ? 2.985 205.696 0.206 1.00 32.30 ? 371 ASN A HD21 1 ATOM 1015 H HD22 . ASN A 1 65 ? 4.402 206.154 0.262 1.00 32.30 ? 371 ASN A HD22 1 ATOM 1016 N N . ASN A 1 66 ? 3.688 207.680 -3.564 1.00 19.06 ? 372 ASN A N 1 ATOM 1017 C CA . ASN A 1 66 ? 3.093 209.020 -3.659 1.00 27.95 ? 372 ASN A CA 1 ATOM 1018 C C . ASN A 1 66 ? 3.960 209.951 -4.496 1.00 27.54 ? 372 ASN A C 1 ATOM 1019 O O . ASN A 1 66 ? 3.933 211.169 -4.308 1.00 33.17 ? 372 ASN A O 1 ATOM 1020 C CB . ASN A 1 66 ? 2.858 209.658 -2.284 1.00 20.91 ? 372 ASN A CB 1 ATOM 1021 C CG . ASN A 1 66 ? 1.937 208.848 -1.416 1.00 30.18 ? 372 ASN A CG 1 ATOM 1022 O OD1 . ASN A 1 66 ? 0.949 208.285 -1.890 1.00 37.92 ? 372 ASN A OD1 1 ATOM 1023 N ND2 . ASN A 1 66 ? 2.273 208.752 -0.133 1.00 27.12 ? 372 ASN A ND2 1 ATOM 1024 H H . ASN A 1 66 ? 3.169 207.056 -3.847 1.00 22.88 ? 372 ASN A H 1 ATOM 1025 H HA . ASN A 1 66 ? 2.232 208.945 -4.100 1.00 33.54 ? 372 ASN A HA 1 ATOM 1026 H HB2 . ASN A 1 66 ? 3.708 209.739 -1.824 1.00 25.10 ? 372 ASN A HB2 1 ATOM 1027 H HB3 . ASN A 1 66 ? 2.461 210.534 -2.406 1.00 25.10 ? 372 ASN A HB3 1 ATOM 1028 H HD21 . ASN A 1 66 ? 1.780 208.300 0.408 1.00 32.54 ? 372 ASN A HD21 1 ATOM 1029 H HD22 . ASN A 1 66 ? 2.983 209.141 0.156 1.00 32.54 ? 372 ASN A HD22 1 ATOM 1030 N N . PHE A 1 67 ? 4.753 209.394 -5.406 1.00 24.60 ? 373 PHE A N 1 ATOM 1031 C CA . PHE A 1 67 ? 5.613 210.210 -6.251 1.00 29.74 ? 373 PHE A CA 1 ATOM 1032 C C . PHE A 1 67 ? 6.016 209.382 -7.458 1.00 23.92 ? 373 PHE A C 1 ATOM 1033 O O . PHE A 1 67 ? 6.213 208.171 -7.357 1.00 27.71 ? 373 PHE A O 1 ATOM 1034 C CB . PHE A 1 67 ? 6.863 210.702 -5.503 1.00 21.21 ? 373 PHE A CB 1 ATOM 1035 C CG . PHE A 1 67 ? 7.524 211.891 -6.138 1.00 24.17 ? 373 PHE A CG 1 ATOM 1036 C CD1 . PHE A 1 67 ? 7.068 213.170 -5.882 1.00 30.26 ? 373 PHE A CD1 1 ATOM 1037 C CD2 . PHE A 1 67 ? 8.605 211.735 -6.985 1.00 33.10 ? 373 PHE A CD2 1 ATOM 1038 C CE1 . PHE A 1 67 ? 7.675 214.278 -6.472 1.00 41.79 ? 373 PHE A CE1 1 ATOM 1039 C CE2 . PHE A 1 67 ? 9.217 212.841 -7.578 1.00 31.64 ? 373 PHE A CE2 1 ATOM 1040 C CZ . PHE A 1 67 ? 8.750 214.112 -7.316 1.00 35.38 ? 373 PHE A CZ 1 ATOM 1041 H H . PHE A 1 67 ? 4.811 208.548 -5.552 1.00 29.52 ? 373 PHE A H 1 ATOM 1042 H HA . PHE A 1 67 ? 5.118 210.984 -6.562 1.00 35.69 ? 373 PHE A HA 1 ATOM 1043 H HB2 . PHE A 1 67 ? 6.608 210.951 -4.601 1.00 25.45 ? 373 PHE A HB2 1 ATOM 1044 H HB3 . PHE A 1 67 ? 7.513 209.982 -5.473 1.00 25.45 ? 373 PHE A HB3 1 ATOM 1045 H HD1 . PHE A 1 67 ? 6.341 213.293 -5.314 1.00 36.31 ? 373 PHE A HD1 1 ATOM 1046 H HD2 . PHE A 1 67 ? 8.924 210.881 -7.168 1.00 39.72 ? 373 PHE A HD2 1 ATOM 1047 H HE1 . PHE A 1 67 ? 7.356 215.133 -6.291 1.00 50.15 ? 373 PHE A HE1 1 ATOM 1048 H HE2 . PHE A 1 67 ? 9.943 212.721 -8.147 1.00 37.96 ? 373 PHE A HE2 1 ATOM 1049 H HZ . PHE A 1 67 ? 9.157 214.851 -7.708 1.00 42.45 ? 373 PHE A HZ 1 ATOM 1050 N N . ASP A 1 68 ? 6.158 210.063 -8.585 1.00 28.47 ? 374 ASP A N 1 ATOM 1051 C CA . ASP A 1 68 ? 6.568 209.456 -9.845 1.00 28.63 ? 374 ASP A CA 1 ATOM 1052 C C . ASP A 1 68 ? 8.091 209.514 -9.923 1.00 31.36 ? 374 ASP A C 1 ATOM 1053 O O . ASP A 1 68 ? 8.674 210.598 -10.047 1.00 27.86 ? 374 ASP A O 1 ATOM 1054 C CB . ASP A 1 68 ? 5.895 210.197 -10.998 1.00 33.12 ? 374 ASP A CB 1 ATOM 1055 C CG . ASP A 1 68 ? 6.448 209.822 -12.364 1.00 41.45 ? 374 ASP A CG 1 ATOM 1056 O OD1 . ASP A 1 68 ? 7.133 208.779 -12.501 1.00 39.84 ? 374 ASP A OD1 1 ATOM 1057 O OD2 . ASP A 1 68 ? 6.168 210.588 -13.314 1.00 46.22 ? 374 ASP A OD2 1 ATOM 1058 H H . ASP A 1 68 ? 6.016 210.909 -8.648 1.00 34.16 ? 374 ASP A H 1 ATOM 1059 H HA . ASP A 1 68 ? 6.290 208.527 -9.867 1.00 34.36 ? 374 ASP A HA 1 ATOM 1060 H HB2 . ASP A 1 68 ? 4.948 209.990 -10.994 1.00 39.74 ? 374 ASP A HB2 1 ATOM 1061 H HB3 . ASP A 1 68 ? 6.025 211.151 -10.876 1.00 39.74 ? 374 ASP A HB3 1 ATOM 1062 N N . GLU A 1 69 ? 8.736 208.347 -9.833 1.00 24.59 ? 375 GLU A N 1 ATOM 1063 C CA . GLU A 1 69 ? 10.196 208.299 -9.815 1.00 23.06 ? 375 GLU A CA 1 ATOM 1064 C C . GLU A 1 69 ? 10.806 209.112 -10.958 1.00 28.04 ? 375 GLU A C 1 ATOM 1065 O O . GLU A 1 69 ? 11.794 209.831 -10.757 1.00 25.31 ? 375 GLU A O 1 ATOM 1066 C CB . GLU A 1 69 ? 10.660 206.848 -9.874 1.00 24.87 ? 375 GLU A CB 1 ATOM 1067 C CG . GLU A 1 69 ? 12.140 206.625 -10.166 1.00 30.60 ? 375 GLU A CG 1 ATOM 1068 C CD . GLU A 1 69 ? 12.462 205.133 -10.333 1.00 34.69 ? 375 GLU A CD 1 ATOM 1069 O OE1 . GLU A 1 69 ? 11.574 204.300 -10.034 1.00 27.70 ? 375 GLU A OE1 1 ATOM 1070 O OE2 . GLU A 1 69 ? 13.591 204.796 -10.767 1.00 36.28 ? 375 GLU A OE2 1 ATOM 1071 H H . GLU A 1 69 ? 8.354 207.578 -9.781 1.00 29.51 ? 375 GLU A H 1 ATOM 1072 H HA . GLU A 1 69 ? 10.512 208.679 -8.980 1.00 27.67 ? 375 GLU A HA 1 ATOM 1073 H HB2 . GLU A 1 69 ? 10.469 206.433 -9.018 1.00 29.84 ? 375 GLU A HB2 1 ATOM 1074 H HB3 . GLU A 1 69 ? 10.157 206.396 -10.570 1.00 29.84 ? 375 GLU A HB3 1 ATOM 1075 H HG2 . GLU A 1 69 ? 12.376 207.081 -10.988 1.00 36.72 ? 375 GLU A HG2 1 ATOM 1076 H HG3 . GLU A 1 69 ? 12.667 206.968 -9.428 1.00 36.72 ? 375 GLU A HG3 1 ATOM 1077 N N . SER A 1 70 ? 10.236 209.015 -12.163 1.00 26.64 ? 376 SER A N 1 ATOM 1078 C CA . SER A 1 70 ? 10.840 209.677 -13.319 1.00 35.04 ? 376 SER A CA 1 ATOM 1079 C C . SER A 1 70 ? 10.774 211.197 -13.233 1.00 28.95 ? 376 SER A C 1 ATOM 1080 O O . SER A 1 70 ? 11.469 211.864 -13.998 1.00 34.17 ? 376 SER A O 1 ATOM 1081 C CB . SER A 1 70 ? 10.176 209.216 -14.616 1.00 29.58 ? 376 SER A CB 1 ATOM 1082 O OG . SER A 1 70 ? 8.850 209.683 -14.704 1.00 32.68 ? 376 SER A OG 1 ATOM 1083 H H . SER A 1 70 ? 9.514 208.580 -12.334 1.00 31.97 ? 376 SER A H 1 ATOM 1084 H HA . SER A 1 70 ? 11.776 209.426 -13.364 1.00 42.05 ? 376 SER A HA 1 ATOM 1085 H HB2 . SER A 1 70 ? 10.682 209.562 -15.369 1.00 35.50 ? 376 SER A HB2 1 ATOM 1086 H HB3 . SER A 1 70 ? 10.170 208.246 -14.640 1.00 35.50 ? 376 SER A HB3 1 ATOM 1087 H HG . SER A 1 70 ? 8.399 209.391 -14.058 1.00 39.21 ? 376 SER A HG 1 ATOM 1088 N N . LYS A 1 71 ? 9.977 211.754 -12.321 1.00 27.43 ? 377 LYS A N 1 ATOM 1089 C CA . LYS A 1 71 ? 9.899 213.196 -12.162 1.00 32.41 ? 377 LYS A CA 1 ATOM 1090 C C . LYS A 1 71 ? 11.016 213.756 -11.291 1.00 34.12 ? 377 LYS A C 1 ATOM 1091 O O . LYS A 1 71 ? 11.151 214.980 -11.206 1.00 28.25 ? 377 LYS A O 1 ATOM 1092 C CB . LYS A 1 71 ? 8.541 213.580 -11.574 1.00 35.70 ? 377 LYS A CB 1 ATOM 1093 C CG . LYS A 1 71 ? 7.716 214.506 -12.442 1.00 42.87 ? 377 LYS A CG 1 ATOM 1094 C CD . LYS A 1 71 ? 7.181 213.820 -13.702 1.00 57.97 ? 377 LYS A CD 1 ATOM 1095 C CE . LYS A 1 71 ? 6.068 214.640 -14.360 1.00 58.74 ? 377 LYS A CE 1 ATOM 1096 N NZ . LYS A 1 71 ? 6.518 216.013 -14.749 1.00 64.14 ? 377 LYS A NZ 1 ATOM 1097 H H . LYS A 1 71 ? 9.471 211.314 -11.783 1.00 32.91 ? 377 LYS A H 1 ATOM 1098 H HA . LYS A 1 71 ? 9.970 213.610 -13.037 1.00 38.90 ? 377 LYS A HA 1 ATOM 1099 H HB2 . LYS A 1 71 ? 8.025 212.770 -11.434 1.00 42.84 ? 377 LYS A HB2 1 ATOM 1100 H HB3 . LYS A 1 71 ? 8.686 214.025 -10.724 1.00 42.84 ? 377 LYS A HB3 1 ATOM 1101 H HG2 . LYS A 1 71 ? 6.957 214.826 -11.930 1.00 51.44 ? 377 LYS A HG2 1 ATOM 1102 H HG3 . LYS A 1 71 ? 8.268 215.254 -12.719 1.00 51.44 ? 377 LYS A HG3 1 ATOM 1103 H HD2 . LYS A 1 71 ? 7.903 213.719 -14.343 1.00 69.56 ? 377 LYS A HD2 1 ATOM 1104 H HD3 . LYS A 1 71 ? 6.819 212.952 -13.465 1.00 69.56 ? 377 LYS A HD3 1 ATOM 1105 H HE2 . LYS A 1 71 ? 5.770 214.183 -15.162 1.00 70.49 ? 377 LYS A HE2 1 ATOM 1106 H HE3 . LYS A 1 71 ? 5.331 214.731 -13.736 1.00 70.49 ? 377 LYS A HE3 1 ATOM 1107 H HZ1 . LYS A 1 71 ? 5.846 216.458 -15.126 1.00 76.97 ? 377 LYS A HZ1 1 ATOM 1108 H HZ2 . LYS A 1 71 ? 6.791 216.459 -14.028 1.00 76.97 ? 377 LYS A HZ2 1 ATOM 1109 H HZ3 . LYS A 1 71 ? 7.192 215.960 -15.328 1.00 76.97 ? 377 LYS A HZ3 1 ATOM 1110 N N . ILE A 1 72 ? 11.822 212.904 -10.651 1.00 31.12 ? 378 ILE A N 1 ATOM 1111 C CA . ILE A 1 72 ? 12.920 213.405 -9.824 1.00 30.91 ? 378 ILE A CA 1 ATOM 1112 C C . ILE A 1 72 ? 13.975 214.068 -10.699 1.00 25.94 ? 378 ILE A C 1 ATOM 1113 O O . ILE A 1 72 ? 14.502 215.134 -10.369 1.00 23.29 ? 378 ILE A O 1 ATOM 1114 C CB . ILE A 1 72 ? 13.539 212.265 -8.991 1.00 25.36 ? 378 ILE A CB 1 ATOM 1115 C CG1 . ILE A 1 72 ? 12.532 211.698 -7.999 1.00 28.22 ? 378 ILE A CG1 1 ATOM 1116 C CG2 . ILE A 1 72 ? 14.775 212.749 -8.250 1.00 19.38 ? 378 ILE A CG2 1 ATOM 1117 C CD1 . ILE A 1 72 ? 12.916 210.331 -7.467 1.00 22.77 ? 378 ILE A CD1 1 ATOM 1118 H H . ILE A 1 72 ? 11.756 212.047 -10.678 1.00 37.34 ? 378 ILE A H 1 ATOM 1119 H HA . ILE A 1 72 ? 12.576 214.073 -9.210 1.00 37.09 ? 378 ILE A HA 1 ATOM 1120 H HB . ILE A 1 72 ? 13.805 211.554 -9.596 1.00 30.43 ? 378 ILE A HB 1 ATOM 1121 H HG12 . ILE A 1 72 ? 12.461 212.302 -7.244 1.00 33.86 ? 378 ILE A HG12 1 ATOM 1122 H HG13 . ILE A 1 72 ? 11.671 211.615 -8.438 1.00 33.86 ? 378 ILE A HG13 1 ATOM 1123 H HG21 . ILE A 1 72 ? 15.143 212.013 -7.736 1.00 23.25 ? 378 ILE A HG21 1 ATOM 1124 H HG22 . ILE A 1 72 ? 15.428 213.061 -8.896 1.00 23.25 ? 378 ILE A HG22 1 ATOM 1125 H HG23 . ILE A 1 72 ? 14.523 213.474 -7.658 1.00 23.25 ? 378 ILE A HG23 1 ATOM 1126 H HD11 . ILE A 1 72 ? 12.235 210.031 -6.845 1.00 27.33 ? 378 ILE A HD11 1 ATOM 1127 H HD12 . ILE A 1 72 ? 12.982 209.710 -8.210 1.00 27.33 ? 378 ILE A HD12 1 ATOM 1128 H HD13 . ILE A 1 72 ? 13.772 210.397 -7.015 1.00 27.33 ? 378 ILE A HD13 1 ATOM 1129 N N . TYR A 1 73 ? 14.334 213.415 -11.799 1.00 27.05 ? 379 TYR A N 1 ATOM 1130 C CA . TYR A 1 73 ? 15.352 213.928 -12.703 1.00 30.28 ? 379 TYR A CA 1 ATOM 1131 C C . TYR A 1 73 ? 15.040 215.371 -13.074 1.00 27.60 ? 379 TYR A C 1 ATOM 1132 O O . TYR A 1 73 ? 13.943 215.677 -13.544 1.00 23.60 ? 379 TYR A O 1 ATOM 1133 C CB . TYR A 1 73 ? 15.420 213.034 -13.947 1.00 30.78 ? 379 TYR A CB 1 ATOM 1134 C CG . TYR A 1 73 ? 15.679 211.587 -13.579 1.00 30.69 ? 379 TYR A CG 1 ATOM 1135 C CD1 . TYR A 1 73 ? 16.969 211.141 -13.305 1.00 32.58 ? 379 TYR A CD1 1 ATOM 1136 C CD2 . TYR A 1 73 ? 14.631 210.679 -13.450 1.00 30.81 ? 379 TYR A CD2 1 ATOM 1137 C CE1 . TYR A 1 73 ? 17.217 209.824 -12.931 1.00 38.45 ? 379 TYR A CE1 1 ATOM 1138 C CE2 . TYR A 1 73 ? 14.869 209.349 -13.071 1.00 33.03 ? 379 TYR A CE2 1 ATOM 1139 C CZ . TYR A 1 73 ? 16.167 208.931 -12.818 1.00 33.24 ? 379 TYR A CZ 1 ATOM 1140 O OH . TYR A 1 73 ? 16.423 207.624 -12.455 1.00 39.68 ? 379 TYR A OH 1 ATOM 1141 H H . TYR A 1 73 ? 13.997 212.663 -12.045 1.00 32.46 ? 379 TYR A H 1 ATOM 1142 H HA . TYR A 1 73 ? 16.216 213.906 -12.262 1.00 36.34 ? 379 TYR A HA 1 ATOM 1143 H HB2 . TYR A 1 73 ? 14.575 213.081 -14.421 1.00 36.93 ? 379 TYR A HB2 1 ATOM 1144 H HB3 . TYR A 1 73 ? 16.143 213.336 -14.519 1.00 36.93 ? 379 TYR A HB3 1 ATOM 1145 H HD1 . TYR A 1 73 ? 17.680 211.736 -13.375 1.00 39.10 ? 379 TYR A HD1 1 ATOM 1146 H HD2 . TYR A 1 73 ? 13.760 210.958 -13.616 1.00 36.97 ? 379 TYR A HD2 1 ATOM 1147 H HE1 . TYR A 1 73 ? 18.088 209.544 -12.762 1.00 46.14 ? 379 TYR A HE1 1 ATOM 1148 H HE2 . TYR A 1 73 ? 14.162 208.749 -12.999 1.00 39.63 ? 379 TYR A HE2 1 ATOM 1149 H HH . TYR A 1 73 ? 15.705 207.189 -12.422 1.00 47.62 ? 379 TYR A HH 1 ATOM 1150 N N . GLY A 1 74 ? 15.985 216.266 -12.800 1.00 26.43 ? 380 GLY A N 1 ATOM 1151 C CA . GLY A 1 74 ? 15.827 217.669 -13.134 1.00 32.46 ? 380 GLY A CA 1 ATOM 1152 C C . GLY A 1 74 ? 15.054 218.516 -12.144 1.00 29.05 ? 380 GLY A C 1 ATOM 1153 O O . GLY A 1 74 ? 14.979 219.735 -12.336 1.00 31.37 ? 380 GLY A O 1 ATOM 1154 H H . GLY A 1 74 ? 16.732 216.080 -12.417 1.00 31.71 ? 380 GLY A H 1 ATOM 1155 H HA2 . GLY A 1 74 ? 16.707 218.064 -13.234 1.00 38.95 ? 380 GLY A HA2 1 ATOM 1156 H HA3 . GLY A 1 74 ? 15.375 217.733 -13.990 1.00 38.95 ? 380 GLY A HA3 1 ATOM 1157 N N . SER A 1 75 ? 14.481 217.932 -11.097 1.00 23.23 ? 381 SER A N 1 ATOM 1158 C CA . SER A 1 75 ? 13.613 218.671 -10.192 1.00 25.96 ? 381 SER A CA 1 ATOM 1159 C C . SER A 1 75 ? 14.395 219.291 -9.034 1.00 23.02 ? 381 SER A C 1 ATOM 1160 O O . SER A 1 75 ? 15.550 218.952 -8.767 1.00 23.23 ? 381 SER A O 1 ATOM 1161 C CB . SER A 1 75 ? 12.518 217.753 -9.650 1.00 28.37 ? 381 SER A CB 1 ATOM 1162 O OG . SER A 1 75 ? 11.632 217.378 -10.688 1.00 35.38 ? 381 SER A OG 1 ATOM 1163 H H . SER A 1 75 ? 14.579 217.103 -10.890 1.00 27.88 ? 381 SER A H 1 ATOM 1164 H HA . SER A 1 75 ? 13.185 219.390 -10.682 1.00 31.15 ? 381 SER A HA 1 ATOM 1165 H HB2 . SER A 1 75 ? 12.927 216.956 -9.278 1.00 34.04 ? 381 SER A HB2 1 ATOM 1166 H HB3 . SER A 1 75 ? 12.020 218.224 -8.963 1.00 34.04 ? 381 SER A HB3 1 ATOM 1167 H HG . SER A 1 75 ? 11.032 216.874 -10.386 1.00 42.45 ? 381 SER A HG 1 ATOM 1168 N N . CYS A 1 76 ? 13.730 220.209 -8.332 1.00 24.98 ? 382 CYS A N 1 ATOM 1169 C CA . CYS A 1 76 ? 14.254 220.843 -7.130 1.00 17.75 ? 382 CYS A CA 1 ATOM 1170 C C . CYS A 1 76 ? 13.341 220.536 -5.954 1.00 21.39 ? 382 CYS A C 1 ATOM 1171 O O . CYS A 1 76 ? 12.122 220.427 -6.108 1.00 20.24 ? 382 CYS A O 1 ATOM 1172 C CB . CYS A 1 76 ? 14.376 222.386 -7.288 1.00 27.14 ? 382 CYS A CB 1 ATOM 1173 S SG . CYS A 1 76 ? 15.630 222.969 -8.485 1.00 27.37 ? 382 CYS A SG 1 ATOM 1174 H H . CYS A 1 76 ? 12.945 220.488 -8.544 1.00 29.98 ? 382 CYS A H 1 ATOM 1175 H HA . CYS A 1 76 ? 15.135 220.486 -6.935 1.00 21.30 ? 382 CYS A HA 1 ATOM 1176 H HB2 . CYS A 1 76 ? 13.517 222.732 -7.577 1.00 32.56 ? 382 CYS A HB2 1 ATOM 1177 H HB3 . CYS A 1 76 ? 14.602 222.764 -6.424 1.00 32.56 ? 382 CYS A HB3 1 ATOM 1178 N N . PHE A 1 77 ? 13.952 220.441 -4.772 1.00 19.92 ? 383 PHE A N 1 ATOM 1179 C CA . PHE A 1 77 ? 13.278 220.100 -3.529 1.00 22.65 ? 383 PHE A CA 1 ATOM 1180 C C . PHE A 1 77 ? 13.774 221.007 -2.411 1.00 21.25 ? 383 PHE A C 1 ATOM 1181 O O . PHE A 1 77 ? 14.915 221.472 -2.435 1.00 24.71 ? 383 PHE A O 1 ATOM 1182 C CB . PHE A 1 77 ? 13.552 218.630 -3.136 1.00 23.39 ? 383 PHE A CB 1 ATOM 1183 C CG . PHE A 1 77 ? 13.084 217.640 -4.143 1.00 16.66 ? 383 PHE A CG 1 ATOM 1184 C CD1 . PHE A 1 77 ? 11.796 217.147 -4.094 1.00 21.23 ? 383 PHE A CD1 1 ATOM 1185 C CD2 . PHE A 1 77 ? 13.925 217.201 -5.136 1.00 16.09 ? 383 PHE A CD2 1 ATOM 1186 C CE1 . PHE A 1 77 ? 11.364 216.239 -5.025 1.00 21.00 ? 383 PHE A CE1 1 ATOM 1187 C CE2 . PHE A 1 77 ? 13.494 216.289 -6.062 1.00 22.02 ? 383 PHE A CE2 1 ATOM 1188 C CZ . PHE A 1 77 ? 12.217 215.816 -6.013 1.00 21.72 ? 383 PHE A CZ 1 ATOM 1189 H H . PHE A 1 77 ? 14.795 220.578 -4.666 1.00 23.91 ? 383 PHE A H 1 ATOM 1190 H HA . PHE A 1 77 ? 12.321 220.223 -3.630 1.00 27.18 ? 383 PHE A HA 1 ATOM 1191 H HB2 . PHE A 1 77 ? 14.508 218.510 -3.025 1.00 28.06 ? 383 PHE A HB2 1 ATOM 1192 H HB3 . PHE A 1 77 ? 13.098 218.440 -2.300 1.00 28.06 ? 383 PHE A HB3 1 ATOM 1193 H HD1 . PHE A 1 77 ? 11.215 217.438 -3.429 1.00 25.48 ? 383 PHE A HD1 1 ATOM 1194 H HD2 . PHE A 1 77 ? 14.796 217.524 -5.179 1.00 19.31 ? 383 PHE A HD2 1 ATOM 1195 H HE1 . PHE A 1 77 ? 10.494 215.912 -4.989 1.00 25.19 ? 383 PHE A HE1 1 ATOM 1196 H HE2 . PHE A 1 77 ? 14.070 216.000 -6.733 1.00 26.43 ? 383 PHE A HE2 1 ATOM 1197 H HZ . PHE A 1 77 ? 11.927 215.195 -6.642 1.00 26.06 ? 383 PHE A HZ 1 ATOM 1198 N N . LYS A 1 78 ? 12.918 221.241 -1.415 1.00 26.47 ? 384 LYS A N 1 ATOM 1199 C CA . LYS A 1 78 ? 13.375 221.948 -0.220 1.00 25.53 ? 384 LYS A CA 1 ATOM 1200 C C . LYS A 1 78 ? 14.425 221.133 0.522 1.00 25.19 ? 384 LYS A C 1 ATOM 1201 O O . LYS A 1 78 ? 15.415 221.684 1.014 1.00 21.91 ? 384 LYS A O 1 ATOM 1202 C CB . LYS A 1 78 ? 12.212 222.250 0.723 1.00 25.39 ? 384 LYS A CB 1 ATOM 1203 C CG . LYS A 1 78 ? 11.085 223.086 0.146 1.00 41.64 ? 384 LYS A CG 1 ATOM 1204 C CD . LYS A 1 78 ? 11.521 224.507 -0.228 1.00 48.29 ? 384 LYS A CD 1 ATOM 1205 C CE . LYS A 1 78 ? 11.960 225.319 0.973 1.00 47.94 ? 384 LYS A CE 1 ATOM 1206 N NZ . LYS A 1 78 ? 12.322 226.708 0.548 1.00 43.23 ? 384 LYS A NZ 1 ATOM 1207 H H . LYS A 1 78 ? 12.090 221.007 -1.405 1.00 31.77 ? 384 LYS A H 1 ATOM 1208 H HA . LYS A 1 78 ? 13.777 222.791 -0.484 1.00 30.64 ? 384 LYS A HA 1 ATOM 1209 H HB2 . LYS A 1 78 ? 11.828 221.408 1.013 1.00 30.47 ? 384 LYS A HB2 1 ATOM 1210 H HB3 . LYS A 1 78 ? 12.560 222.727 1.493 1.00 30.47 ? 384 LYS A HB3 1 ATOM 1211 H HG2 . LYS A 1 78 ? 10.752 222.655 -0.656 1.00 49.96 ? 384 LYS A HG2 1 ATOM 1212 H HG3 . LYS A 1 78 ? 10.375 223.155 0.804 1.00 49.96 ? 384 LYS A HG3 1 ATOM 1213 H HD2 . LYS A 1 78 ? 12.268 224.457 -0.845 1.00 57.95 ? 384 LYS A HD2 1 ATOM 1214 H HD3 . LYS A 1 78 ? 10.776 224.967 -0.645 1.00 57.95 ? 384 LYS A HD3 1 ATOM 1215 H HE2 . LYS A 1 78 ? 11.232 225.372 1.613 1.00 57.53 ? 384 LYS A HE2 1 ATOM 1216 H HE3 . LYS A 1 78 ? 12.739 224.907 1.377 1.00 57.53 ? 384 LYS A HE3 1 ATOM 1217 H HZ1 . LYS A 1 78 ? 12.580 227.184 1.254 1.00 51.88 ? 384 LYS A HZ1 1 ATOM 1218 H HZ2 . LYS A 1 78 ? 12.988 226.681 -0.041 1.00 51.88 ? 384 LYS A HZ2 1 ATOM 1219 H HZ3 . LYS A 1 78 ? 11.619 227.104 0.172 1.00 51.88 ? 384 LYS A HZ3 1 ATOM 1220 N N . SER A 1 79 ? 14.222 219.822 0.624 1.00 21.10 ? 385 SER A N 1 ATOM 1221 C CA . SER A 1 79 ? 15.213 218.963 1.255 1.00 23.32 ? 385 SER A CA 1 ATOM 1222 C C . SER A 1 79 ? 14.908 217.506 0.928 1.00 21.03 ? 385 SER A C 1 ATOM 1223 O O . SER A 1 79 ? 13.767 217.136 0.626 1.00 15.80 ? 385 SER A O 1 ATOM 1224 C CB . SER A 1 79 ? 15.231 219.164 2.770 1.00 20.50 ? 385 SER A CB 1 ATOM 1225 O OG . SER A 1 79 ? 13.986 218.764 3.313 1.00 25.30 ? 385 SER A OG 1 ATOM 1226 H H . SER A 1 79 ? 13.524 219.410 0.337 1.00 25.32 ? 385 SER A H 1 ATOM 1227 H HA . SER A 1 79 ? 16.093 219.177 0.907 1.00 27.98 ? 385 SER A HA 1 ATOM 1228 H HB2 . SER A 1 79 ? 15.937 218.623 3.157 1.00 24.60 ? 385 SER A HB2 1 ATOM 1229 H HB3 . SER A 1 79 ? 15.379 220.102 2.967 1.00 24.60 ? 385 SER A HB3 1 ATOM 1230 H HG . SER A 1 79 ? 13.988 218.872 4.146 1.00 30.36 ? 385 SER A HG 1 ATOM 1231 N N . ILE A 1 80 ? 15.945 216.681 1.033 1.00 21.42 ? 386 ILE A N 1 ATOM 1232 C CA . ILE A 1 80 ? 15.836 215.238 0.874 1.00 19.85 ? 386 ILE A CA 1 ATOM 1233 C C . ILE A 1 80 ? 16.372 214.602 2.153 1.00 21.11 ? 386 ILE A C 1 ATOM 1234 O O . ILE A 1 80 ? 17.565 214.720 2.467 1.00 20.72 ? 386 ILE A O 1 ATOM 1235 C CB . ILE A 1 80 ? 16.578 214.742 -0.372 1.00 20.24 ? 386 ILE A CB 1 ATOM 1236 C CG1 . ILE A 1 80 ? 16.000 215.422 -1.618 1.00 20.79 ? 386 ILE A CG1 1 ATOM 1237 C CG2 . ILE A 1 80 ? 16.415 213.260 -0.525 1.00 26.29 ? 386 ILE A CG2 1 ATOM 1238 C CD1 . ILE A 1 80 ? 16.677 215.037 -2.944 1.00 25.74 ? 386 ILE A CD1 1 ATOM 1239 H H . ILE A 1 80 ? 16.746 216.944 1.201 1.00 25.71 ? 386 ILE A H 1 ATOM 1240 H HA . ILE A 1 80 ? 14.900 214.996 0.784 1.00 23.82 ? 386 ILE A HA 1 ATOM 1241 H HB . ILE A 1 80 ? 17.521 214.958 -0.294 1.00 24.29 ? 386 ILE A HB 1 ATOM 1242 H HG12 . ILE A 1 80 ? 15.062 215.187 -1.690 1.00 24.95 ? 386 ILE A HG12 1 ATOM 1243 H HG13 . ILE A 1 80 ? 16.087 216.383 -1.513 1.00 24.95 ? 386 ILE A HG13 1 ATOM 1244 H HG21 . ILE A 1 80 ? 16.893 212.971 -1.318 1.00 31.55 ? 386 ILE A HG21 1 ATOM 1245 H HG22 . ILE A 1 80 ? 16.778 212.821 0.260 1.00 31.55 ? 386 ILE A HG22 1 ATOM 1246 H HG23 . ILE A 1 80 ? 15.471 213.055 -0.613 1.00 31.55 ? 386 ILE A HG23 1 ATOM 1247 H HD11 . ILE A 1 80 ? 16.245 215.515 -3.669 1.00 30.89 ? 386 ILE A HD11 1 ATOM 1248 H HD12 . ILE A 1 80 ? 17.616 215.279 -2.900 1.00 30.89 ? 386 ILE A HD12 1 ATOM 1249 H HD13 . ILE A 1 80 ? 16.588 214.081 -3.077 1.00 30.89 ? 386 ILE A HD13 1 ATOM 1250 N N . VAL A 1 81 ? 15.482 213.962 2.906 1.00 18.60 ? 387 VAL A N 1 ATOM 1251 C CA . VAL A 1 81 ? 15.815 213.312 4.171 1.00 17.67 ? 387 VAL A CA 1 ATOM 1252 C C . VAL A 1 81 ? 16.003 211.823 3.904 1.00 21.16 ? 387 VAL A C 1 ATOM 1253 O O . VAL A 1 81 ? 15.079 211.149 3.432 1.00 18.36 ? 387 VAL A O 1 ATOM 1254 C CB . VAL A 1 81 ? 14.715 213.547 5.214 1.00 20.40 ? 387 VAL A CB 1 ATOM 1255 C CG1 . VAL A 1 81 ? 15.059 212.868 6.538 1.00 19.32 ? 387 VAL A CG1 1 ATOM 1256 C CG2 . VAL A 1 81 ? 14.466 215.044 5.385 1.00 22.04 ? 387 VAL A CG2 1 ATOM 1257 H H . VAL A 1 81 ? 14.651 213.889 2.697 1.00 22.32 ? 387 VAL A H 1 ATOM 1258 H HA . VAL A 1 81 ? 16.647 213.672 4.514 1.00 21.21 ? 387 VAL A HA 1 ATOM 1259 H HB . VAL A 1 81 ? 13.892 213.150 4.888 1.00 24.48 ? 387 VAL A HB 1 ATOM 1260 H HG11 . VAL A 1 81 ? 14.346 213.036 7.173 1.00 23.18 ? 387 VAL A HG11 1 ATOM 1261 H HG12 . VAL A 1 81 ? 15.152 211.914 6.388 1.00 23.18 ? 387 VAL A HG12 1 ATOM 1262 H HG13 . VAL A 1 81 ? 15.893 213.234 6.872 1.00 23.18 ? 387 VAL A HG13 1 ATOM 1263 H HG21 . VAL A 1 81 ? 13.768 215.174 6.046 1.00 26.45 ? 387 VAL A HG21 1 ATOM 1264 H HG22 . VAL A 1 81 ? 15.286 215.468 5.680 1.00 26.45 ? 387 VAL A HG22 1 ATOM 1265 H HG23 . VAL A 1 81 ? 14.188 215.417 4.533 1.00 26.45 ? 387 VAL A HG23 1 ATOM 1266 N N . LEU A 1 82 ? 17.197 211.314 4.193 1.00 19.94 ? 388 LEU A N 1 ATOM 1267 C CA . LEU A 1 82 ? 17.537 209.911 4.001 1.00 22.11 ? 388 LEU A CA 1 ATOM 1268 C C . LEU A 1 82 ? 17.647 209.189 5.338 1.00 16.90 ? 388 LEU A C 1 ATOM 1269 O O . LEU A 1 82 ? 18.348 209.648 6.238 1.00 16.29 ? 388 LEU A O 1 ATOM 1270 C CB . LEU A 1 82 ? 18.859 209.757 3.255 1.00 20.66 ? 388 LEU A CB 1 ATOM 1271 C CG . LEU A 1 82 ? 18.733 209.428 1.781 1.00 27.87 ? 388 LEU A CG 1 ATOM 1272 C CD1 . LEU A 1 82 ? 18.119 210.615 1.039 1.00 30.93 ? 388 LEU A CD1 1 ATOM 1273 C CD2 . LEU A 1 82 ? 20.100 209.093 1.232 1.00 33.58 ? 388 LEU A CD2 1 ATOM 1274 H H . LEU A 1 82 ? 17.846 211.780 4.513 1.00 23.93 ? 388 LEU A H 1 ATOM 1275 H HA . LEU A 1 82 ? 16.841 209.481 3.479 1.00 26.53 ? 388 LEU A HA 1 ATOM 1276 H HB2 . LEU A 1 82 ? 19.352 210.589 3.327 1.00 24.80 ? 388 LEU A HB2 1 ATOM 1277 H HB3 . LEU A 1 82 ? 19.366 209.042 3.671 1.00 24.80 ? 388 LEU A HB3 1 ATOM 1278 H HG . LEU A 1 82 ? 18.155 208.657 1.666 1.00 33.45 ? 388 LEU A HG 1 ATOM 1279 H HD11 . LEU A 1 82 ? 18.044 210.394 0.097 1.00 37.12 ? 388 LEU A HD11 1 ATOM 1280 H HD12 . LEU A 1 82 ? 17.241 210.798 1.408 1.00 37.12 ? 388 LEU A HD12 1 ATOM 1281 H HD13 . LEU A 1 82 ? 18.694 211.389 1.152 1.00 37.12 ? 388 LEU A HD13 1 ATOM 1282 H HD21 . LEU A 1 82 ? 20.018 208.883 0.289 1.00 40.30 ? 388 LEU A HD21 1 ATOM 1283 H HD22 . LEU A 1 82 ? 20.684 209.858 1.351 1.00 40.30 ? 388 LEU A HD22 1 ATOM 1284 H HD23 . LEU A 1 82 ? 20.454 208.328 1.712 1.00 40.30 ? 388 LEU A HD23 1 ATOM 1285 N N . ASP A 1 83 ? 16.999 208.035 5.431 1.00 18.80 ? 389 ASP A N 1 ATOM 1286 C CA . ASP A 1 83 ? 17.135 207.118 6.551 1.00 17.04 ? 389 ASP A CA 1 ATOM 1287 C C . ASP A 1 83 ? 17.690 205.807 6.023 1.00 22.11 ? 389 ASP A C 1 ATOM 1288 O O . ASP A 1 83 ? 17.275 205.346 4.960 1.00 22.07 ? 389 ASP A O 1 ATOM 1289 C CB . ASP A 1 83 ? 15.792 206.879 7.226 1.00 15.07 ? 389 ASP A CB 1 ATOM 1290 C CG . ASP A 1 83 ? 15.202 208.150 7.805 1.00 20.37 ? 389 ASP A CG 1 ATOM 1291 O OD1 . ASP A 1 83 ? 15.995 209.037 8.216 1.00 21.26 ? 389 ASP A OD1 1 ATOM 1292 O OD2 . ASP A 1 83 ? 13.956 208.254 7.852 1.00 13.93 ? 389 ASP A OD2 1 ATOM 1293 H H . ASP A 1 83 ? 16.452 207.751 4.831 1.00 22.57 ? 389 ASP A H 1 ATOM 1294 H HA . ASP A 1 83 ? 17.754 207.482 7.202 1.00 20.45 ? 389 ASP A HA 1 ATOM 1295 H HB2 . ASP A 1 83 ? 15.167 206.527 6.573 1.00 18.09 ? 389 ASP A HB2 1 ATOM 1296 H HB3 . ASP A 1 83 ? 15.910 206.245 7.951 1.00 18.09 ? 389 ASP A HB3 1 ATOM 1297 N N . LYS A 1 84 ? 18.632 205.211 6.752 1.00 21.73 ? 390 LYS A N 1 ATOM 1298 C CA . LYS A 1 84 ? 19.253 203.978 6.299 1.00 19.92 ? 390 LYS A CA 1 ATOM 1299 C C . LYS A 1 84 ? 19.477 203.019 7.462 1.00 17.63 ? 390 LYS A C 1 ATOM 1300 O O . LYS A 1 84 ? 19.495 203.407 8.632 1.00 14.47 ? 390 LYS A O 1 ATOM 1301 C CB . LYS A 1 84 ? 20.583 204.259 5.591 1.00 20.25 ? 390 LYS A CB 1 ATOM 1302 C CG . LYS A 1 84 ? 21.675 204.743 6.505 1.00 20.33 ? 390 LYS A CG 1 ATOM 1303 C CD . LYS A 1 84 ? 22.991 204.900 5.777 1.00 16.95 ? 390 LYS A CD 1 ATOM 1304 C CE . LYS A 1 84 ? 24.085 205.355 6.742 1.00 27.50 ? 390 LYS A CE 1 ATOM 1305 N NZ . LYS A 1 84 ? 25.456 205.284 6.165 1.00 26.80 ? 390 LYS A NZ 1 ATOM 1306 H H . LYS A 1 84 ? 18.925 205.501 7.506 1.00 26.08 ? 390 LYS A H 1 ATOM 1307 H HA . LYS A 1 84 ? 18.662 203.544 5.664 1.00 23.90 ? 390 LYS A HA 1 ATOM 1308 H HB2 . LYS A 1 84 ? 20.891 203.441 5.171 1.00 24.30 ? 390 LYS A HB2 1 ATOM 1309 H HB3 . LYS A 1 84 ? 20.439 204.940 4.916 1.00 24.30 ? 390 LYS A HB3 1 ATOM 1310 H HG2 . LYS A 1 84 ? 21.426 205.607 6.870 1.00 24.39 ? 390 LYS A HG2 1 ATOM 1311 H HG3 . LYS A 1 84 ? 21.800 204.101 7.221 1.00 24.39 ? 390 LYS A HG3 1 ATOM 1312 H HD2 . LYS A 1 84 ? 23.253 204.048 5.395 1.00 20.34 ? 390 LYS A HD2 1 ATOM 1313 H HD3 . LYS A 1 84 ? 22.898 205.569 5.081 1.00 20.34 ? 390 LYS A HD3 1 ATOM 1314 H HE2 . LYS A 1 84 ? 23.916 206.276 6.995 1.00 33.00 ? 390 LYS A HE2 1 ATOM 1315 H HE3 . LYS A 1 84 ? 24.064 204.788 7.529 1.00 33.00 ? 390 LYS A HE3 1 ATOM 1316 H HZ1 . LYS A 1 84 ? 26.053 205.559 6.765 1.00 32.17 ? 390 LYS A HZ1 1 ATOM 1317 H HZ2 . LYS A 1 84 ? 25.644 204.447 5.932 1.00 32.17 ? 390 LYS A HZ2 1 ATOM 1318 H HZ3 . LYS A 1 84 ? 25.509 205.804 5.444 1.00 32.17 ? 390 LYS A HZ3 1 ATOM 1319 N N . PHE A 1 85 ? 19.634 201.745 7.100 1.00 16.07 ? 391 PHE A N 1 ATOM 1320 C CA . PHE A 1 85 ? 20.042 200.682 8.003 1.00 14.13 ? 391 PHE A CA 1 ATOM 1321 C C . PHE A 1 85 ? 20.211 199.352 7.263 1.00 17.81 ? 391 PHE A C 1 ATOM 1322 O O . PHE A 1 85 ? 19.540 199.110 6.253 1.00 11.86 ? 391 PHE A O 1 ATOM 1323 C CB . PHE A 1 85 ? 19.028 200.505 9.135 1.00 13.55 ? 391 PHE A CB 1 ATOM 1324 C CG . PHE A 1 85 ? 17.606 200.361 8.675 1.00 13.21 ? 391 PHE A CG 1 ATOM 1325 C CD1 . PHE A 1 85 ? 17.125 199.134 8.236 1.00 14.81 ? 391 PHE A CD1 1 ATOM 1326 C CD2 . PHE A 1 85 ? 16.733 201.443 8.713 1.00 13.20 ? 391 PHE A CD2 1 ATOM 1327 C CE1 . PHE A 1 85 ? 15.805 199.000 7.843 1.00 14.41 ? 391 PHE A CE1 1 ATOM 1328 C CE2 . PHE A 1 85 ? 15.421 201.307 8.333 1.00 7.33 ? 391 PHE A CE2 1 ATOM 1329 C CZ . PHE A 1 85 ? 14.958 200.088 7.900 1.00 16.29 ? 391 PHE A CZ 1 ATOM 1330 H H . PHE A 1 85 ? 19.502 201.466 6.297 1.00 19.28 ? 391 PHE A H 1 ATOM 1331 H HA . PHE A 1 85 ? 20.896 200.915 8.399 1.00 16.96 ? 391 PHE A HA 1 ATOM 1332 H HB2 . PHE A 1 85 ? 19.258 199.707 9.636 1.00 16.25 ? 391 PHE A HB2 1 ATOM 1333 H HB3 . PHE A 1 85 ? 19.073 201.280 9.716 1.00 16.25 ? 391 PHE A HB3 1 ATOM 1334 H HD1 . PHE A 1 85 ? 17.692 198.398 8.210 1.00 17.77 ? 391 PHE A HD1 1 ATOM 1335 H HD2 . PHE A 1 85 ? 17.038 202.267 9.018 1.00 15.84 ? 391 PHE A HD2 1 ATOM 1336 H HE1 . PHE A 1 85 ? 15.488 198.178 7.547 1.00 17.29 ? 391 PHE A HE1 1 ATOM 1337 H HE2 . PHE A 1 85 ? 14.849 202.040 8.359 1.00 8.80 ? 391 PHE A HE2 1 ATOM 1338 H HZ . PHE A 1 85 ? 14.075 200.001 7.625 1.00 19.55 ? 391 PHE A HZ 1 ATOM 1339 N N . ALA A 1 86 ? 21.092 198.486 7.773 1.00 15.83 ? 392 ALA A N 1 ATOM 1340 C CA . ALA A 1 86 ? 21.240 197.136 7.249 1.00 16.19 ? 392 ALA A CA 1 ATOM 1341 C C . ALA A 1 86 ? 19.969 196.332 7.486 1.00 17.54 ? 392 ALA A C 1 ATOM 1342 O O . ALA A 1 86 ? 19.216 196.581 8.431 1.00 13.33 ? 392 ALA A O 1 ATOM 1343 C CB . ALA A 1 86 ? 22.422 196.430 7.905 1.00 16.07 ? 392 ALA A CB 1 ATOM 1344 H H . ALA A 1 86 ? 21.618 198.664 8.430 1.00 18.99 ? 392 ALA A H 1 ATOM 1345 H HA . ALA A 1 86 ? 21.401 197.178 6.293 1.00 19.42 ? 392 ALA A HA 1 ATOM 1346 H HB1 . ALA A 1 86 ? 22.498 195.535 7.539 1.00 19.28 ? 392 ALA A HB1 1 ATOM 1347 H HB2 . ALA A 1 86 ? 23.231 196.932 7.722 1.00 19.28 ? 392 ALA A HB2 1 ATOM 1348 H HB3 . ALA A 1 86 ? 22.270 196.384 8.862 1.00 19.28 ? 392 ALA A HB3 1 ATOM 1349 N N . ILE A 1 87 ? 19.733 195.364 6.612 1.00 15.50 ? 393 ILE A N 1 ATOM 1350 C CA . ILE A 1 87 ? 18.528 194.540 6.633 1.00 15.15 ? 393 ILE A CA 1 ATOM 1351 C C . ILE A 1 87 ? 18.902 193.159 7.158 1.00 18.56 ? 393 ILE A C 1 ATOM 1352 O O . ILE A 1 87 ? 19.668 192.441 6.501 1.00 18.17 ? 393 ILE A O 1 ATOM 1353 C CB . ILE A 1 87 ? 17.879 194.425 5.245 1.00 14.61 ? 393 ILE A CB 1 ATOM 1354 C CG1 . ILE A 1 87 ? 17.729 195.791 4.593 1.00 19.51 ? 393 ILE A CG1 1 ATOM 1355 C CG2 . ILE A 1 87 ? 16.528 193.756 5.376 1.00 14.90 ? 393 ILE A CG2 1 ATOM 1356 C CD1 . ILE A 1 87 ? 17.275 195.735 3.162 1.00 15.11 ? 393 ILE A CD1 1 ATOM 1357 H H . ILE A 1 87 ? 20.273 195.157 5.976 1.00 18.60 ? 393 ILE A H 1 ATOM 1358 H HA . ILE A 1 87 ? 17.881 194.932 7.240 1.00 18.18 ? 393 ILE A HA 1 ATOM 1359 H HB . ILE A 1 87 ? 18.445 193.873 4.682 1.00 17.54 ? 393 ILE A HB 1 ATOM 1360 H HG12 . ILE A 1 87 ? 17.075 196.304 5.092 1.00 23.41 ? 393 ILE A HG12 1 ATOM 1361 H HG13 . ILE A 1 87 ? 18.587 196.243 4.614 1.00 23.41 ? 393 ILE A HG13 1 ATOM 1362 H HG21 . ILE A 1 87 ? 16.123 193.686 4.497 1.00 17.88 ? 393 ILE A HG21 1 ATOM 1363 H HG22 . ILE A 1 87 ? 16.649 192.872 5.756 1.00 17.88 ? 393 ILE A HG22 1 ATOM 1364 H HG23 . ILE A 1 87 ? 15.966 194.292 5.958 1.00 17.88 ? 393 ILE A HG23 1 ATOM 1365 H HD11 . ILE A 1 87 ? 17.203 196.640 2.818 1.00 18.14 ? 393 ILE A HD11 1 ATOM 1366 H HD12 . ILE A 1 87 ? 17.925 195.235 2.644 1.00 18.14 ? 393 ILE A HD12 1 ATOM 1367 H HD13 . ILE A 1 87 ? 16.411 195.297 3.122 1.00 18.14 ? 393 ILE A HD13 1 ATOM 1368 N N . PRO A 1 88 ? 18.387 192.734 8.313 1.00 13.09 ? 394 PRO A N 1 ATOM 1369 C CA . PRO A 1 88 ? 18.530 191.328 8.706 1.00 16.04 ? 394 PRO A CA 1 ATOM 1370 C C . PRO A 1 88 ? 17.757 190.450 7.736 1.00 17.00 ? 394 PRO A C 1 ATOM 1371 O O . PRO A 1 88 ? 16.574 190.690 7.495 1.00 17.74 ? 394 PRO A O 1 ATOM 1372 C CB . PRO A 1 88 ? 17.932 191.280 10.122 1.00 20.85 ? 394 PRO A CB 1 ATOM 1373 C CG . PRO A 1 88 ? 17.813 192.695 10.571 1.00 14.84 ? 394 PRO A CG 1 ATOM 1374 C CD . PRO A 1 88 ? 17.639 193.509 9.309 1.00 12.56 ? 394 PRO A CD 1 ATOM 1375 H HA . PRO A 1 88 ? 19.463 191.064 8.728 1.00 19.24 ? 394 PRO A HA 1 ATOM 1376 H HB2 . PRO A 1 88 ? 17.059 190.859 10.091 1.00 25.02 ? 394 PRO A HB2 1 ATOM 1377 H HB3 . PRO A 1 88 ? 18.527 190.787 10.708 1.00 25.02 ? 394 PRO A HB3 1 ATOM 1378 H HG2 . PRO A 1 88 ? 17.039 192.790 11.147 1.00 17.81 ? 394 PRO A HG2 1 ATOM 1379 H HG3 . PRO A 1 88 ? 18.622 192.958 11.038 1.00 17.81 ? 394 PRO A HG3 1 ATOM 1380 H HD2 . PRO A 1 88 ? 16.702 193.561 9.065 1.00 15.08 ? 394 PRO A HD2 1 ATOM 1381 H HD3 . PRO A 1 88 ? 18.030 194.390 9.417 1.00 15.08 ? 394 PRO A HD3 1 ATOM 1382 N N . ASN A 1 89 ? 18.434 189.424 7.189 1.00 17.25 ? 395 ASN A N 1 ATOM 1383 C CA . ASN A 1 89 ? 17.856 188.624 6.101 1.00 19.43 ? 395 ASN A CA 1 ATOM 1384 C C . ASN A 1 89 ? 16.430 188.191 6.418 1.00 16.16 ? 395 ASN A C 1 ATOM 1385 O O . ASN A 1 89 ? 15.530 188.313 5.581 1.00 21.27 ? 395 ASN A O 1 ATOM 1386 C CB . ASN A 1 89 ? 18.714 187.380 5.814 1.00 16.88 ? 395 ASN A CB 1 ATOM 1387 C CG . ASN A 1 89 ? 20.036 187.701 5.124 1.00 17.11 ? 395 ASN A CG 1 ATOM 1388 O OD1 . ASN A 1 89 ? 20.256 188.810 4.657 1.00 18.41 ? 395 ASN A OD1 1 ATOM 1389 N ND2 . ASN A 1 89 ? 20.926 186.716 5.062 1.00 18.72 ? 395 ASN A ND2 1 ATOM 1390 H H . ASN A 1 89 ? 19.221 189.175 7.430 1.00 20.71 ? 395 ASN A H 1 ATOM 1391 H HA . ASN A 1 89 ? 17.832 189.162 5.295 1.00 23.32 ? 395 ASN A HA 1 ATOM 1392 H HB2 . ASN A 1 89 ? 18.916 186.937 6.653 1.00 20.26 ? 395 ASN A HB2 1 ATOM 1393 H HB3 . ASN A 1 89 ? 18.215 186.781 5.237 1.00 20.26 ? 395 ASN A HB3 1 ATOM 1394 H HD21 . ASN A 1 89 ? 21.687 186.846 4.683 1.00 22.46 ? 395 ASN A HD21 1 ATOM 1395 H HD22 . ASN A 1 89 ? 20.741 185.947 5.402 1.00 22.46 ? 395 ASN A HD22 1 ATOM 1396 N N . SER A 1 90 ? 16.206 187.670 7.626 1.00 14.47 ? 396 SER A N 1 ATOM 1397 C CA . SER A 1 90 ? 14.889 187.180 8.019 1.00 16.01 ? 396 SER A CA 1 ATOM 1398 C C . SER A 1 90 ? 13.820 188.277 8.091 1.00 19.50 ? 396 SER A C 1 ATOM 1399 O O . SER A 1 90 ? 12.631 187.948 8.208 1.00 18.65 ? 396 SER A O 1 ATOM 1400 C CB . SER A 1 90 ? 15.001 186.474 9.383 1.00 18.27 ? 396 SER A CB 1 ATOM 1401 O OG . SER A 1 90 ? 15.262 187.440 10.405 1.00 27.56 ? 396 SER A OG 1 ATOM 1402 H H . SER A 1 90 ? 16.806 187.590 8.238 1.00 17.37 ? 396 SER A H 1 ATOM 1403 H HA . SER A 1 90 ? 14.594 186.523 7.368 1.00 19.22 ? 396 SER A HA 1 ATOM 1404 H HB2 . SER A 1 90 ? 14.166 186.021 9.578 1.00 21.92 ? 396 SER A HB2 1 ATOM 1405 H HB3 . SER A 1 90 ? 15.731 185.836 9.353 1.00 21.92 ? 396 SER A HB3 1 ATOM 1406 H HG . SER A 1 90 ? 15.982 187.842 10.244 1.00 33.08 ? 396 SER A HG 1 ATOM 1407 N N . ARG A 1 91 ? 14.189 189.559 8.020 1.00 14.32 ? 397 ARG A N 1 ATOM 1408 C CA . ARG A 1 91 ? 13.226 190.636 8.216 1.00 18.28 ? 397 ARG A CA 1 ATOM 1409 C C . ARG A 1 91 ? 12.842 191.388 6.949 1.00 18.51 ? 397 ARG A C 1 ATOM 1410 O O . ARG A 1 91 ? 12.075 192.352 7.039 1.00 15.50 ? 397 ARG A O 1 ATOM 1411 C CB . ARG A 1 91 ? 13.775 191.635 9.240 1.00 16.74 ? 397 ARG A CB 1 ATOM 1412 C CG . ARG A 1 91 ? 14.134 190.993 10.547 1.00 16.78 ? 397 ARG A CG 1 ATOM 1413 C CD . ARG A 1 91 ? 13.018 191.129 11.522 1.00 16.50 ? 397 ARG A CD 1 ATOM 1414 N NE . ARG A 1 91 ? 11.779 190.391 11.249 1.00 15.24 ? 397 ARG A NE 1 ATOM 1415 C CZ . ARG A 1 91 ? 11.607 189.090 11.470 1.00 18.25 ? 397 ARG A CZ 1 ATOM 1416 N NH1 . ARG A 1 91 ? 12.614 188.326 11.871 1.00 18.41 ? 397 ARG A NH1 1 ATOM 1417 N NH2 . ARG A 1 91 ? 10.421 188.544 11.275 1.00 18.41 ? 397 ARG A NH2 1 ATOM 1418 H H . ARG A 1 91 ? 14.990 189.828 7.859 1.00 17.19 ? 397 ARG A H 1 ATOM 1419 H HA . ARG A 1 91 ? 12.414 190.256 8.585 1.00 21.94 ? 397 ARG A HA 1 ATOM 1420 H HB2 . ARG A 1 91 ? 14.576 192.048 8.880 1.00 20.08 ? 397 ARG A HB2 1 ATOM 1421 H HB3 . ARG A 1 91 ? 13.102 192.312 9.414 1.00 20.08 ? 397 ARG A HB3 1 ATOM 1422 H HG2 . ARG A 1 91 ? 14.304 190.048 10.406 1.00 20.13 ? 397 ARG A HG2 1 ATOM 1423 H HG3 . ARG A 1 91 ? 14.918 191.427 10.916 1.00 20.13 ? 397 ARG A HG3 1 ATOM 1424 H HD2 . ARG A 1 91 ? 13.339 190.833 12.388 1.00 19.80 ? 397 ARG A HD2 1 ATOM 1425 H HD3 . ARG A 1 91 ? 12.781 192.068 11.576 1.00 19.80 ? 397 ARG A HD3 1 ATOM 1426 H HE . ARG A 1 91 ? 11.117 190.831 10.923 1.00 18.29 ? 397 ARG A HE 1 ATOM 1427 H HH11 . ARG A 1 91 ? 13.385 188.676 12.024 1.00 22.10 ? 397 ARG A HH11 1 ATOM 1428 H HH12 . ARG A 1 91 ? 12.492 187.484 11.995 1.00 22.10 ? 397 ARG A HH12 1 ATOM 1429 H HH21 . ARG A 1 91 ? 9.767 189.026 10.991 1.00 22.09 ? 397 ARG A HH21 1 ATOM 1430 H HH22 . ARG A 1 91 ? 10.317 187.696 11.374 1.00 22.09 ? 397 ARG A HH22 1 ATOM 1431 N N . ARG A 1 92 ? 13.321 190.959 5.783 1.00 19.56 ? 398 ARG A N 1 ATOM 1432 C CA . ARG A 1 92 ? 13.178 191.748 4.553 1.00 22.28 ? 398 ARG A CA 1 ATOM 1433 C C . ARG A 1 92 ? 11.721 192.107 4.257 1.00 21.15 ? 398 ARG A C 1 ATOM 1434 O O . ARG A 1 92 ? 11.417 193.256 3.903 1.00 19.65 ? 398 ARG A O 1 ATOM 1435 C CB . ARG A 1 92 ? 13.797 190.979 3.382 1.00 21.33 ? 398 ARG A CB 1 ATOM 1436 C CG . ARG A 1 92 ? 13.470 191.536 2.000 1.00 26.29 ? 398 ARG A CG 1 ATOM 1437 C CD . ARG A 1 92 ? 13.962 192.946 1.826 1.00 33.23 ? 398 ARG A CD 1 ATOM 1438 N NE . ARG A 1 92 ? 13.653 193.437 0.482 1.00 36.34 ? 398 ARG A NE 1 ATOM 1439 C CZ . ARG A 1 92 ? 12.504 194.013 0.136 1.00 34.21 ? 398 ARG A CZ 1 ATOM 1440 N NH1 . ARG A 1 92 ? 11.538 194.181 1.039 1.00 24.24 ? 398 ARG A NH1 1 ATOM 1441 N NH2 . ARG A 1 92 ? 12.322 194.422 -1.120 1.00 39.27 ? 398 ARG A NH2 1 ATOM 1442 H H . ARG A 1 92 ? 13.735 190.214 5.674 1.00 23.48 ? 398 ARG A H 1 ATOM 1443 H HA . ARG A 1 92 ? 13.671 192.577 4.656 1.00 26.74 ? 398 ARG A HA 1 ATOM 1444 H HB2 . ARG A 1 92 ? 14.762 190.991 3.481 1.00 25.60 ? 398 ARG A HB2 1 ATOM 1445 H HB3 . ARG A 1 92 ? 13.478 190.064 3.412 1.00 25.60 ? 398 ARG A HB3 1 ATOM 1446 H HG2 . ARG A 1 92 ? 13.895 190.983 1.326 1.00 31.55 ? 398 ARG A HG2 1 ATOM 1447 H HG3 . ARG A 1 92 ? 12.508 191.534 1.875 1.00 31.55 ? 398 ARG A HG3 1 ATOM 1448 H HD2 . ARG A 1 92 ? 13.524 193.522 2.471 1.00 39.88 ? 398 ARG A HD2 1 ATOM 1449 H HD3 . ARG A 1 92 ? 14.924 192.970 1.948 1.00 39.88 ? 398 ARG A HD3 1 ATOM 1450 H HE . ARG A 1 92 ? 14.256 193.348 -0.125 1.00 43.61 ? 398 ARG A HE 1 ATOM 1451 H HH11 . ARG A 1 92 ? 11.656 193.916 1.849 1.00 29.09 ? 398 ARG A HH11 1 ATOM 1452 H HH12 . ARG A 1 92 ? 10.797 194.554 0.812 1.00 29.09 ? 398 ARG A HH12 1 ATOM 1453 H HH21 . ARG A 1 92 ? 12.946 194.314 -1.702 1.00 47.13 ? 398 ARG A HH21 1 ATOM 1454 H HH22 . ARG A 1 92 ? 11.582 194.796 -1.347 1.00 47.13 ? 398 ARG A HH22 1 ATOM 1455 N N . SER A 1 93 ? 10.800 191.153 4.418 1.00 17.27 ? 399 SER A N 1 ATOM 1456 C CA . SER A 1 93 ? 9.392 191.409 4.123 1.00 18.24 ? 399 SER A CA 1 ATOM 1457 C C . SER A 1 93 ? 8.712 192.324 5.139 1.00 19.57 ? 399 SER A C 1 ATOM 1458 O O . SER A 1 93 ? 7.588 192.775 4.876 1.00 13.78 ? 399 SER A O 1 ATOM 1459 C CB . SER A 1 93 ? 8.635 190.088 4.047 1.00 17.37 ? 399 SER A CB 1 ATOM 1460 O OG . SER A 1 93 ? 8.651 189.422 5.312 1.00 28.99 ? 399 SER A OG 1 ATOM 1461 H H . SER A 1 93 ? 10.965 190.355 4.694 1.00 20.72 ? 399 SER A H 1 ATOM 1462 H HA . SER A 1 93 ? 9.329 191.836 3.254 1.00 21.89 ? 399 SER A HA 1 ATOM 1463 H HB2 . SER A 1 93 ? 7.715 190.265 3.795 1.00 20.84 ? 399 SER A HB2 1 ATOM 1464 H HB3 . SER A 1 93 ? 9.057 189.519 3.384 1.00 20.84 ? 399 SER A HB3 1 ATOM 1465 H HG . SER A 1 93 ? 9.443 189.263 5.542 1.00 34.79 ? 399 SER A HG 1 ATOM 1466 N N . ASP A 1 94 ? 9.339 192.574 6.297 1.00 18.70 ? 400 ASP A N 1 ATOM 1467 C CA . ASP A 1 94 ? 8.867 193.620 7.200 1.00 15.82 ? 400 ASP A CA 1 ATOM 1468 C C . ASP A 1 94 ? 8.883 195.005 6.560 1.00 15.90 ? 400 ASP A C 1 ATOM 1469 O O . ASP A 1 94 ? 8.211 195.912 7.063 1.00 14.81 ? 400 ASP A O 1 ATOM 1470 C CB . ASP A 1 94 ? 9.740 193.698 8.454 1.00 19.78 ? 400 ASP A CB 1 ATOM 1471 C CG . ASP A 1 94 ? 9.513 192.565 9.424 1.00 20.34 ? 400 ASP A CG 1 ATOM 1472 O OD1 . ASP A 1 94 ? 8.723 191.640 9.127 1.00 22.07 ? 400 ASP A OD1 1 ATOM 1473 O OD2 . ASP A 1 94 ? 10.162 192.599 10.496 1.00 19.22 ? 400 ASP A OD2 1 ATOM 1474 H H . ASP A 1 94 ? 10.034 192.152 6.576 1.00 22.43 ? 400 ASP A H 1 ATOM 1475 H HA . ASP A 1 94 ? 7.958 193.422 7.474 1.00 18.98 ? 400 ASP A HA 1 ATOM 1476 H HB2 . ASP A 1 94 ? 10.673 193.679 8.188 1.00 23.74 ? 400 ASP A HB2 1 ATOM 1477 H HB3 . ASP A 1 94 ? 9.548 194.529 8.918 1.00 23.74 ? 400 ASP A HB3 1 ATOM 1478 N N . LEU A 1 95 ? 9.656 195.207 5.494 1.00 20.44 ? 401 LEU A N 1 ATOM 1479 C CA . LEU A 1 95 ? 9.827 196.544 4.940 1.00 20.95 ? 401 LEU A CA 1 ATOM 1480 C C . LEU A 1 95 ? 8.798 196.879 3.879 1.00 19.16 ? 401 LEU A C 1 ATOM 1481 O O . LEU A 1 95 ? 8.837 197.983 3.325 1.00 26.62 ? 401 LEU A O 1 ATOM 1482 C CB . LEU A 1 95 ? 11.234 196.711 4.372 1.00 17.92 ? 401 LEU A CB 1 ATOM 1483 C CG . LEU A 1 95 ? 12.299 196.560 5.464 1.00 18.80 ? 401 LEU A CG 1 ATOM 1484 C CD1 . LEU A 1 95 ? 13.667 196.465 4.880 1.00 22.38 ? 401 LEU A CD1 1 ATOM 1485 C CD2 . LEU A 1 95 ? 12.237 197.725 6.455 1.00 22.10 ? 401 LEU A CD2 1 ATOM 1486 H H . LEU A 1 95 ? 10.088 194.591 5.078 1.00 24.53 ? 401 LEU A H 1 ATOM 1487 H HA . LEU A 1 95 ? 9.724 197.188 5.658 1.00 25.14 ? 401 LEU A HA 1 ATOM 1488 H HB2 . LEU A 1 95 ? 11.390 196.030 3.698 1.00 21.51 ? 401 LEU A HB2 1 ATOM 1489 H HB3 . LEU A 1 95 ? 11.320 197.595 3.983 1.00 21.51 ? 401 LEU A HB3 1 ATOM 1490 H HG . LEU A 1 95 ? 12.128 195.742 5.956 1.00 22.56 ? 401 LEU A HG 1 ATOM 1491 H HD11 . LEU A 1 95 ? 14.311 196.371 5.600 1.00 26.85 ? 401 LEU A HD11 1 ATOM 1492 H HD12 . LEU A 1 95 ? 13.708 195.691 4.296 1.00 26.85 ? 401 LEU A HD12 1 ATOM 1493 H HD13 . LEU A 1 95 ? 13.851 197.271 4.374 1.00 26.85 ? 401 LEU A HD13 1 ATOM 1494 H HD21 . LEU A 1 95 ? 12.922 197.600 7.131 1.00 26.52 ? 401 LEU A HD21 1 ATOM 1495 H HD22 . LEU A 1 95 ? 12.392 198.555 5.976 1.00 26.52 ? 401 LEU A HD22 1 ATOM 1496 H HD23 . LEU A 1 95 ? 11.361 197.741 6.870 1.00 26.52 ? 401 LEU A HD23 1 ATOM 1497 N N . GLN A 1 96 ? 7.863 195.983 3.594 1.00 21.74 ? 402 GLN A N 1 ATOM 1498 C CA . GLN A 1 96 ? 6.770 196.369 2.716 1.00 21.54 ? 402 GLN A CA 1 ATOM 1499 C C . GLN A 1 96 ? 5.963 197.463 3.390 1.00 26.66 ? 402 GLN A C 1 ATOM 1500 O O . GLN A 1 96 ? 5.786 197.476 4.618 1.00 18.50 ? 402 GLN A O 1 ATOM 1501 C CB . GLN A 1 96 ? 5.866 195.183 2.395 1.00 20.90 ? 402 GLN A CB 1 ATOM 1502 C CG . GLN A 1 96 ? 6.546 194.054 1.685 1.00 27.99 ? 402 GLN A CG 1 ATOM 1503 C CD . GLN A 1 96 ? 5.593 192.895 1.400 1.00 36.02 ? 402 GLN A CD 1 ATOM 1504 O OE1 . GLN A 1 96 ? 4.763 192.521 2.238 1.00 41.46 ? 402 GLN A OE1 1 ATOM 1505 N NE2 . GLN A 1 96 ? 5.698 192.339 0.205 1.00 36.82 ? 402 GLN A NE2 1 ATOM 1506 H H . GLN A 1 96 ? 7.837 195.174 3.883 1.00 26.09 ? 402 GLN A H 1 ATOM 1507 H HA . GLN A 1 96 ? 7.129 196.717 1.885 1.00 25.85 ? 402 GLN A HA 1 ATOM 1508 H HB2 . GLN A 1 96 ? 5.507 194.834 3.225 1.00 25.08 ? 402 GLN A HB2 1 ATOM 1509 H HB3 . GLN A 1 96 ? 5.141 195.491 1.829 1.00 25.08 ? 402 GLN A HB3 1 ATOM 1510 H HG2 . GLN A 1 96 ? 6.894 194.374 0.839 1.00 33.59 ? 402 GLN A HG2 1 ATOM 1511 H HG3 . GLN A 1 96 ? 7.269 193.721 2.239 1.00 33.59 ? 402 GLN A HG3 1 ATOM 1512 H HE21 . GLN A 1 96 ? 6.277 192.635 -0.358 1.00 44.18 ? 402 GLN A HE21 1 ATOM 1513 H HE22 . GLN A 1 96 ? 5.186 191.682 -0.010 1.00 44.18 ? 402 GLN A HE22 1 ATOM 1514 N N . LEU A 1 97 ? 5.487 198.393 2.579 1.00 14.86 ? 403 LEU A N 1 ATOM 1515 C CA . LEU A 1 97 ? 4.742 199.513 3.109 1.00 24.42 ? 403 LEU A CA 1 ATOM 1516 C C . LEU A 1 97 ? 3.512 199.013 3.857 1.00 25.69 ? 403 LEU A C 1 ATOM 1517 O O . LEU A 1 97 ? 2.772 198.152 3.367 1.00 20.26 ? 403 LEU A O 1 ATOM 1518 C CB . LEU A 1 97 ? 4.355 200.466 1.976 1.00 21.33 ? 403 LEU A CB 1 ATOM 1519 C CG . LEU A 1 97 ? 5.234 201.723 1.844 1.00 33.26 ? 403 LEU A CG 1 ATOM 1520 C CD1 . LEU A 1 97 ? 6.713 201.389 1.883 1.00 24.78 ? 403 LEU A CD1 1 ATOM 1521 C CD2 . LEU A 1 97 ? 4.911 202.507 0.536 1.00 34.98 ? 403 LEU A CD2 1 ATOM 1522 H H . LEU A 1 97 ? 5.582 198.398 1.724 1.00 17.83 ? 403 LEU A H 1 ATOM 1523 H HA . LEU A 1 97 ? 5.300 199.999 3.736 1.00 29.31 ? 403 LEU A HA 1 ATOM 1524 H HB2 . LEU A 1 97 ? 4.410 199.983 1.137 1.00 25.60 ? 403 LEU A HB2 1 ATOM 1525 H HB3 . LEU A 1 97 ? 3.443 200.762 2.122 1.00 25.60 ? 403 LEU A HB3 1 ATOM 1526 H HG . LEU A 1 97 ? 5.047 202.311 2.593 1.00 39.91 ? 403 LEU A HG 1 ATOM 1527 H HD11 . LEU A 1 97 ? 7.224 202.209 1.797 1.00 29.74 ? 403 LEU A HD11 1 ATOM 1528 H HD12 . LEU A 1 97 ? 6.917 200.958 2.728 1.00 29.74 ? 403 LEU A HD12 1 ATOM 1529 H HD13 . LEU A 1 97 ? 6.921 200.790 1.148 1.00 29.74 ? 403 LEU A HD13 1 ATOM 1530 H HD21 . LEU A 1 97 ? 5.483 203.290 0.488 1.00 41.97 ? 403 LEU A HD21 1 ATOM 1531 H HD22 . LEU A 1 97 ? 5.076 201.930 -0.226 1.00 41.97 ? 403 LEU A HD22 1 ATOM 1532 H HD23 . LEU A 1 97 ? 3.980 202.778 0.552 1.00 41.97 ? 403 LEU A HD23 1 ATOM 1533 N N . GLY A 1 98 ? 3.312 199.552 5.057 1.00 17.92 ? 404 GLY A N 1 ATOM 1534 C CA . GLY A 1 98 ? 2.177 199.227 5.890 1.00 24.01 ? 404 GLY A CA 1 ATOM 1535 C C . GLY A 1 98 ? 2.313 197.957 6.709 1.00 23.27 ? 404 GLY A C 1 ATOM 1536 O O . GLY A 1 98 ? 1.367 197.599 7.419 1.00 23.22 ? 404 GLY A O 1 ATOM 1537 H H . GLY A 1 98 ? 3.842 200.127 5.414 1.00 21.51 ? 404 GLY A H 1 ATOM 1538 H HA2 . GLY A 1 98 ? 2.019 199.961 6.504 1.00 28.81 ? 404 GLY A HA2 1 ATOM 1539 H HA3 . GLY A 1 98 ? 1.392 199.135 5.327 1.00 28.81 ? 404 GLY A HA3 1 ATOM 1540 N N . SER A 1 99 ? 3.459 197.281 6.647 1.00 20.78 ? 405 SER A N 1 ATOM 1541 C CA . SER A 1 99 ? 3.632 196.001 7.325 1.00 27.19 ? 405 SER A CA 1 ATOM 1542 C C . SER A 1 99 ? 3.649 196.160 8.845 1.00 27.12 ? 405 SER A C 1 ATOM 1543 O O . SER A 1 99 ? 4.266 197.076 9.384 1.00 23.72 ? 405 SER A O 1 ATOM 1544 C CB . SER A 1 99 ? 4.935 195.345 6.893 1.00 17.90 ? 405 SER A CB 1 ATOM 1545 O OG . SER A 1 99 ? 5.271 194.299 7.775 1.00 21.15 ? 405 SER A OG 1 ATOM 1546 H H . SER A 1 99 ? 4.154 197.545 6.215 1.00 24.94 ? 405 SER A H 1 ATOM 1547 H HA . SER A 1 99 ? 2.900 195.410 7.088 1.00 32.63 ? 405 SER A HA 1 ATOM 1548 H HB2 . SER A 1 99 ? 4.828 194.985 5.999 1.00 21.47 ? 405 SER A HB2 1 ATOM 1549 H HB3 . SER A 1 99 ? 5.642 196.009 6.903 1.00 21.47 ? 405 SER A HB3 1 ATOM 1550 H HG . SER A 1 99 ? 5.991 193.940 7.533 1.00 25.38 ? 405 SER A HG 1 ATOM 1551 N N . SER A 1 100 ? 3.019 195.217 9.533 1.00 26.51 ? 406 SER A N 1 ATOM 1552 C CA . SER A 1 100 ? 2.973 195.198 10.987 1.00 30.60 ? 406 SER A CA 1 ATOM 1553 C C . SER A 1 100 ? 4.081 194.348 11.605 1.00 23.89 ? 406 SER A C 1 ATOM 1554 O O . SER A 1 100 ? 4.072 194.136 12.817 1.00 24.21 ? 406 SER A O 1 ATOM 1555 C CB . SER A 1 100 ? 1.605 194.694 11.453 1.00 30.99 ? 406 SER A CB 1 ATOM 1556 O OG . SER A 1 100 ? 0.736 195.778 11.725 1.00 40.40 ? 406 SER A OG 1 ATOM 1557 H H . SER A 1 100 ? 2.599 194.561 9.170 1.00 31.81 ? 406 SER A H 1 ATOM 1558 H HA . SER A 1 100 ? 3.081 196.105 11.313 1.00 36.72 ? 406 SER A HA 1 ATOM 1559 H HB2 . SER A 1 100 ? 1.216 194.144 10.755 1.00 37.19 ? 406 SER A HB2 1 ATOM 1560 H HB3 . SER A 1 100 ? 1.720 194.171 12.262 1.00 37.19 ? 406 SER A HB3 1 ATOM 1561 H HG . SER A 1 100 ? -0.011 195.491 11.980 1.00 48.48 ? 406 SER A HG 1 ATOM 1562 N N . GLY A 1 101 ? 5.035 193.869 10.809 1.00 19.71 ? 407 GLY A N 1 ATOM 1563 C CA . GLY A 1 101 ? 6.106 193.043 11.327 1.00 16.15 ? 407 GLY A CA 1 ATOM 1564 C C . GLY A 1 101 ? 7.016 193.761 12.301 1.00 19.23 ? 407 GLY A C 1 ATOM 1565 O O . GLY A 1 101 ? 6.773 194.914 12.673 1.00 19.58 ? 407 GLY A O 1 ATOM 1566 H H . GLY A 1 101 ? 5.079 194.012 9.963 1.00 23.66 ? 407 GLY A H 1 ATOM 1567 H HA2 . GLY A 1 101 ? 5.725 192.274 11.780 1.00 19.39 ? 407 GLY A HA2 1 ATOM 1568 H HA3 . GLY A 1 101 ? 6.646 192.722 10.588 1.00 19.39 ? 407 GLY A HA3 1 ATOM 1569 N N . PHE A 1 102 ? 8.102 193.093 12.685 1.00 16.58 ? 408 PHE A N 1 ATOM 1570 C CA . PHE A 1 102 ? 8.934 193.588 13.774 1.00 16.05 ? 408 PHE A CA 1 ATOM 1571 C C . PHE A 1 102 ? 9.660 194.877 13.396 1.00 15.05 ? 408 PHE A C 1 ATOM 1572 O O . PHE A 1 102 ? 9.753 195.800 14.214 1.00 14.63 ? 408 PHE A O 1 ATOM 1573 C CB . PHE A 1 102 ? 9.947 192.513 14.193 1.00 15.24 ? 408 PHE A CB 1 ATOM 1574 C CG . PHE A 1 102 ? 9.349 191.355 14.961 1.00 13.53 ? 408 PHE A CG 1 ATOM 1575 C CD1 . PHE A 1 102 ? 8.395 191.561 15.943 1.00 12.33 ? 408 PHE A CD1 1 ATOM 1576 C CD2 . PHE A 1 102 ? 9.766 190.042 14.699 1.00 16.29 ? 408 PHE A CD2 1 ATOM 1577 C CE1 . PHE A 1 102 ? 7.849 190.471 16.671 1.00 16.07 ? 408 PHE A CE1 1 ATOM 1578 C CE2 . PHE A 1 102 ? 9.229 188.964 15.406 1.00 16.35 ? 408 PHE A CE2 1 ATOM 1579 C CZ . PHE A 1 102 ? 8.270 189.190 16.407 1.00 17.56 ? 408 PHE A CZ 1 ATOM 1580 H H . PHE A 1 102 ? 8.375 192.357 12.334 1.00 19.90 ? 408 PHE A H 1 ATOM 1581 H HA . PHE A 1 102 ? 8.369 193.778 14.539 1.00 19.25 ? 408 PHE A HA 1 ATOM 1582 H HB2 . PHE A 1 102 ? 10.364 192.152 13.395 1.00 18.29 ? 408 PHE A HB2 1 ATOM 1583 H HB3 . PHE A 1 102 ? 10.620 192.924 14.757 1.00 18.29 ? 408 PHE A HB3 1 ATOM 1584 H HD1 . PHE A 1 102 ? 8.112 192.426 16.133 1.00 14.79 ? 408 PHE A HD1 1 ATOM 1585 H HD2 . PHE A 1 102 ? 10.407 189.886 14.043 1.00 19.55 ? 408 PHE A HD2 1 ATOM 1586 H HE1 . PHE A 1 102 ? 7.209 190.625 17.327 1.00 19.28 ? 408 PHE A HE1 1 ATOM 1587 H HE2 . PHE A 1 102 ? 9.516 188.099 15.223 1.00 19.62 ? 408 PHE A HE2 1 ATOM 1588 H HZ . PHE A 1 102 ? 7.907 188.474 16.876 1.00 21.07 ? 408 PHE A HZ 1 ATOM 1589 N N . LEU A 1 103 ? 10.191 194.971 12.173 1.00 14.74 ? 409 LEU A N 1 ATOM 1590 C CA . LEU A 1 103 ? 11.022 196.127 11.852 1.00 13.35 ? 409 LEU A CA 1 ATOM 1591 C C . LEU A 1 103 ? 10.230 197.420 11.960 1.00 13.48 ? 409 LEU A C 1 ATOM 1592 O O . LEU A 1 103 ? 10.732 198.417 12.492 1.00 12.45 ? 409 LEU A O 1 ATOM 1593 C CB . LEU A 1 103 ? 11.641 196.006 10.473 1.00 17.36 ? 409 LEU A CB 1 ATOM 1594 C CG . LEU A 1 103 ? 12.810 195.041 10.323 1.00 20.77 ? 409 LEU A CG 1 ATOM 1595 C CD1 . LEU A 1 103 ? 13.453 195.308 8.983 1.00 16.58 ? 409 LEU A CD1 1 ATOM 1596 C CD2 . LEU A 1 103 ? 13.850 195.165 11.437 1.00 19.54 ? 409 LEU A CD2 1 ATOM 1597 H H . LEU A 1 103 ? 10.089 194.401 11.537 1.00 17.69 ? 409 LEU A H 1 ATOM 1598 H HA . LEU A 1 103 ? 11.747 196.174 12.494 1.00 16.02 ? 409 LEU A HA 1 ATOM 1599 H HB2 . LEU A 1 103 ? 10.950 195.716 9.857 1.00 20.84 ? 409 LEU A HB2 1 ATOM 1600 H HB3 . LEU A 1 103 ? 11.959 196.883 10.207 1.00 20.84 ? 409 LEU A HB3 1 ATOM 1601 H HG . LEU A 1 103 ? 12.474 194.131 10.322 1.00 24.92 ? 409 LEU A HG 1 ATOM 1602 H HD11 . LEU A 1 103 ? 14.202 194.703 8.866 1.00 19.89 ? 409 LEU A HD11 1 ATOM 1603 H HD12 . LEU A 1 103 ? 12.797 195.162 8.283 1.00 19.89 ? 409 LEU A HD12 1 ATOM 1604 H HD13 . LEU A 1 103 ? 13.763 196.227 8.960 1.00 19.89 ? 409 LEU A HD13 1 ATOM 1605 H HD21 . LEU A 1 103 ? 14.561 194.524 11.278 1.00 23.45 ? 409 LEU A HD21 1 ATOM 1606 H HD22 . LEU A 1 103 ? 14.210 196.066 11.434 1.00 23.45 ? 409 LEU A HD22 1 ATOM 1607 H HD23 . LEU A 1 103 ? 13.424 194.981 12.289 1.00 23.45 ? 409 LEU A HD23 1 ATOM 1608 N N . GLN A 1 104 ? 8.975 197.413 11.525 1.00 12.52 ? 410 GLN A N 1 ATOM 1609 C CA . GLN A 1 104 ? 8.211 198.650 11.539 1.00 20.86 ? 410 GLN A CA 1 ATOM 1610 C C . GLN A 1 104 ? 7.361 198.799 12.785 1.00 17.67 ? 410 GLN A C 1 ATOM 1611 O O . GLN A 1 104 ? 6.932 199.916 13.086 1.00 17.19 ? 410 GLN A O 1 ATOM 1612 C CB . GLN A 1 104 ? 7.331 198.764 10.281 1.00 14.05 ? 410 GLN A CB 1 ATOM 1613 C CG . GLN A 1 104 ? 8.131 198.843 9.012 1.00 17.08 ? 410 GLN A CG 1 ATOM 1614 C CD . GLN A 1 104 ? 7.336 199.406 7.834 1.00 16.43 ? 410 GLN A CD 1 ATOM 1615 O OE1 . GLN A 1 104 ? 6.887 200.545 7.867 1.00 20.15 ? 410 GLN A OE1 1 ATOM 1616 N NE2 . GLN A 1 104 ? 7.163 198.593 6.783 1.00 17.59 ? 410 GLN A NE2 1 ATOM 1617 H H . GLN A 1 104 ? 8.553 196.725 11.226 1.00 15.03 ? 410 GLN A H 1 ATOM 1618 H HA . GLN A 1 104 ? 8.835 199.393 11.524 1.00 25.04 ? 410 GLN A HA 1 ATOM 1619 H HB2 . GLN A 1 104 ? 6.758 197.984 10.225 1.00 16.86 ? 410 GLN A HB2 1 ATOM 1620 H HB3 . GLN A 1 104 ? 6.792 199.568 10.345 1.00 16.86 ? 410 GLN A HB3 1 ATOM 1621 H HG2 . GLN A 1 104 ? 8.897 199.420 9.158 1.00 20.49 ? 410 GLN A HG2 1 ATOM 1622 H HG3 . GLN A 1 104 ? 8.429 197.952 8.772 1.00 20.49 ? 410 GLN A HG3 1 ATOM 1623 H HE21 . GLN A 1 104 ? 7.492 197.798 6.795 1.00 21.11 ? 410 GLN A HE21 1 ATOM 1624 H HE22 . GLN A 1 104 ? 6.722 198.866 6.097 1.00 21.11 ? 410 GLN A HE22 1 ATOM 1625 N N . SER A 1 105 ? 7.118 197.709 13.515 1.00 16.20 ? 411 SER A N 1 ATOM 1626 C CA . SER A 1 105 ? 6.427 197.799 14.790 1.00 14.08 ? 411 SER A CA 1 ATOM 1627 C C . SER A 1 105 ? 7.315 198.391 15.864 1.00 16.75 ? 411 SER A C 1 ATOM 1628 O O . SER A 1 105 ? 6.807 199.009 16.804 1.00 24.35 ? 411 SER A O 1 ATOM 1629 C CB . SER A 1 105 ? 5.959 196.416 15.247 1.00 18.36 ? 411 SER A CB 1 ATOM 1630 O OG . SER A 1 105 ? 4.702 196.078 14.693 1.00 15.61 ? 411 SER A OG 1 ATOM 1631 H H . SER A 1 105 ? 7.345 196.910 13.290 1.00 19.44 ? 411 SER A H 1 ATOM 1632 H HA . SER A 1 105 ? 5.647 198.368 14.692 1.00 16.90 ? 411 SER A HA 1 ATOM 1633 H HB2 . SER A 1 105 ? 6.612 195.756 14.966 1.00 22.03 ? 411 SER A HB2 1 ATOM 1634 H HB3 . SER A 1 105 ? 5.885 196.414 16.214 1.00 22.03 ? 411 SER A HB3 1 ATOM 1635 H HG . SER A 1 105 ? 4.750 196.073 13.854 1.00 18.73 ? 411 SER A HG 1 ATOM 1636 N N . SER A 1 106 ? 8.625 198.243 15.723 1.00 16.98 ? 412 SER A N 1 ATOM 1637 C CA . SER A 1 106 ? 9.515 198.383 16.864 1.00 16.66 ? 412 SER A CA 1 ATOM 1638 C C . SER A 1 106 ? 10.896 198.922 16.536 1.00 17.92 ? 412 SER A C 1 ATOM 1639 O O . SER A 1 106 ? 11.730 198.971 17.441 1.00 15.76 ? 412 SER A O 1 ATOM 1640 C CB . SER A 1 106 ? 9.643 197.003 17.537 1.00 14.18 ? 412 SER A CB 1 ATOM 1641 O OG . SER A 1 106 ? 8.367 196.582 17.979 1.00 15.22 ? 412 SER A OG 1 ATOM 1642 H H . SER A 1 106 ? 9.022 198.062 14.982 1.00 20.37 ? 412 SER A H 1 ATOM 1643 H HA . SER A 1 106 ? 9.107 198.987 17.504 1.00 19.99 ? 412 SER A HA 1 ATOM 1644 H HB2 . SER A 1 106 ? 9.988 196.363 16.895 1.00 17.02 ? 412 SER A HB2 1 ATOM 1645 H HB3 . SER A 1 106 ? 10.240 197.071 18.299 1.00 17.02 ? 412 SER A HB3 1 ATOM 1646 H HG . SER A 1 106 ? 8.424 195.829 18.348 1.00 18.26 ? 412 SER A HG 1 ATOM 1647 N N . ASN A 1 107 ? 11.190 199.282 15.282 1.00 15.23 ? 413 ASN A N 1 ATOM 1648 C CA . ASN A 1 107 ? 12.490 199.843 14.949 1.00 15.04 ? 413 ASN A CA 1 ATOM 1649 C C . ASN A 1 107 ? 12.362 201.093 14.085 1.00 14.95 ? 413 ASN A C 1 ATOM 1650 O O . ASN A 1 107 ? 12.883 202.144 14.455 1.00 11.09 ? 413 ASN A O 1 ATOM 1651 C CB . ASN A 1 107 ? 13.350 198.810 14.235 1.00 12.26 ? 413 ASN A CB 1 ATOM 1652 C CG . ASN A 1 107 ? 13.505 197.536 15.031 1.00 16.59 ? 413 ASN A CG 1 ATOM 1653 O OD1 . ASN A 1 107 ? 14.539 197.307 15.651 1.00 15.90 ? 413 ASN A OD1 1 ATOM 1654 N ND2 . ASN A 1 107 ? 12.478 196.690 15.004 1.00 13.82 ? 413 ASN A ND2 1 ATOM 1655 H H . ASN A 1 107 ? 10.654 199.209 14.614 1.00 18.27 ? 413 ASN A H 1 ATOM 1656 H HA . ASN A 1 107 ? 12.943 200.093 15.769 1.00 18.05 ? 413 ASN A HA 1 ATOM 1657 H HB2 . ASN A 1 107 ? 12.936 198.586 13.387 1.00 14.71 ? 413 ASN A HB2 1 ATOM 1658 H HB3 . ASN A 1 107 ? 14.233 199.181 14.087 1.00 14.71 ? 413 ASN A HB3 1 ATOM 1659 H HD21 . ASN A 1 107 ? 12.518 195.951 15.442 1.00 16.58 ? 413 ASN A HD21 1 ATOM 1660 H HD22 . ASN A 1 107 ? 11.774 196.883 14.549 1.00 16.58 ? 413 ASN A HD22 1 ATOM 1661 N N . TYR A 1 108 ? 11.713 200.966 12.919 1.00 17.23 ? 414 TYR A N 1 ATOM 1662 C CA . TYR A 1 108 ? 11.606 202.048 11.945 1.00 15.42 ? 414 TYR A CA 1 ATOM 1663 C C . TYR A 1 108 ? 10.300 201.892 11.194 1.00 18.93 ? 414 TYR A C 1 ATOM 1664 O O . TYR A 1 108 ? 10.100 200.873 10.530 1.00 15.55 ? 414 TYR A O 1 ATOM 1665 C CB . TYR A 1 108 ? 12.772 202.043 10.968 1.00 15.69 ? 414 TYR A CB 1 ATOM 1666 C CG . TYR A 1 108 ? 12.704 203.146 9.925 1.00 12.10 ? 414 TYR A CG 1 ATOM 1667 C CD1 . TYR A 1 108 ? 13.298 204.377 10.157 1.00 17.77 ? 414 TYR A CD1 1 ATOM 1668 C CD2 . TYR A 1 108 ? 12.055 202.957 8.718 1.00 15.56 ? 414 TYR A CD2 1 ATOM 1669 C CE1 . TYR A 1 108 ? 13.251 205.410 9.219 1.00 18.20 ? 414 TYR A CE1 1 ATOM 1670 C CE2 . TYR A 1 108 ? 12.001 203.986 7.745 1.00 16.44 ? 414 TYR A CE2 1 ATOM 1671 C CZ . TYR A 1 108 ? 12.600 205.212 8.005 1.00 16.88 ? 414 TYR A CZ 1 ATOM 1672 O OH . TYR A 1 108 ? 12.553 206.230 7.063 1.00 15.71 ? 414 TYR A OH 1 ATOM 1673 H H . TYR A 1 108 ? 11.320 200.243 12.670 1.00 20.68 ? 414 TYR A H 1 ATOM 1674 H HA . TYR A 1 108 ? 11.596 202.900 12.408 1.00 18.51 ? 414 TYR A HA 1 ATOM 1675 H HB2 . TYR A 1 108 ? 13.597 202.157 11.465 1.00 18.83 ? 414 TYR A HB2 1 ATOM 1676 H HB3 . TYR A 1 108 ? 12.785 201.194 10.500 1.00 18.83 ? 414 TYR A HB3 1 ATOM 1677 H HD1 . TYR A 1 108 ? 13.737 204.522 10.965 1.00 21.32 ? 414 TYR A HD1 1 ATOM 1678 H HD2 . TYR A 1 108 ? 11.653 202.138 8.539 1.00 18.67 ? 414 TYR A HD2 1 ATOM 1679 H HE1 . TYR A 1 108 ? 13.660 206.225 9.402 1.00 21.84 ? 414 TYR A HE1 1 ATOM 1680 H HE2 . TYR A 1 108 ? 11.560 203.844 6.939 1.00 19.72 ? 414 TYR A HE2 1 ATOM 1681 H HH . TYR A 1 108 ? 12.956 206.908 7.352 1.00 18.85 ? 414 TYR A HH 1 ATOM 1682 N N . LYS A 1 109 ? 9.435 202.903 11.281 1.00 15.46 ? 415 LYS A N 1 ATOM 1683 C CA . LYS A 1 109 ? 8.147 202.885 10.609 1.00 19.38 ? 415 LYS A CA 1 ATOM 1684 C C . LYS A 1 109 ? 8.239 203.730 9.340 1.00 17.12 ? 415 LYS A C 1 ATOM 1685 O O . LYS A 1 109 ? 8.510 204.937 9.415 1.00 16.49 ? 415 LYS A O 1 ATOM 1686 C CB . LYS A 1 109 ? 7.044 203.412 11.524 1.00 16.67 ? 415 LYS A CB 1 ATOM 1687 C CG . LYS A 1 109 ? 5.655 203.095 10.999 1.00 30.89 ? 415 LYS A CG 1 ATOM 1688 C CD . LYS A 1 109 ? 4.586 203.904 11.688 1.00 40.70 ? 415 LYS A CD 1 ATOM 1689 C CE . LYS A 1 109 ? 3.200 203.523 11.170 1.00 50.60 ? 415 LYS A CE 1 ATOM 1690 N NZ . LYS A 1 109 ? 2.158 204.538 11.541 1.00 67.52 ? 415 LYS A NZ 1 ATOM 1691 H H . LYS A 1 109 ? 9.579 203.621 11.733 1.00 18.55 ? 415 LYS A H 1 ATOM 1692 H HA . LYS A 1 109 ? 7.927 201.975 10.356 1.00 23.25 ? 415 LYS A HA 1 ATOM 1693 H HB2 . LYS A 1 109 ? 7.135 203.003 12.399 1.00 20.00 ? 415 LYS A HB2 1 ATOM 1694 H HB3 . LYS A 1 109 ? 7.125 204.376 11.597 1.00 20.00 ? 415 LYS A HB3 1 ATOM 1695 H HG2 . LYS A 1 109 ? 5.621 203.296 10.051 1.00 37.07 ? 415 LYS A HG2 1 ATOM 1696 H HG3 . LYS A 1 109 ? 5.466 202.156 11.148 1.00 37.07 ? 415 LYS A HG3 1 ATOM 1697 H HD2 . LYS A 1 109 ? 4.614 203.731 12.642 1.00 48.84 ? 415 LYS A HD2 1 ATOM 1698 H HD3 . LYS A 1 109 ? 4.730 204.847 11.511 1.00 48.84 ? 415 LYS A HD3 1 ATOM 1699 H HE2 . LYS A 1 109 ? 3.229 203.459 10.202 1.00 60.72 ? 415 LYS A HE2 1 ATOM 1700 H HE3 . LYS A 1 109 ? 2.941 202.670 11.553 1.00 60.72 ? 415 LYS A HE3 1 ATOM 1701 H HZ1 . LYS A 1 109 ? 1.365 204.288 11.226 1.00 81.03 ? 415 LYS A HZ1 1 ATOM 1702 H HZ2 . LYS A 1 109 ? 2.108 204.612 12.426 1.00 81.03 ? 415 LYS A HZ2 1 ATOM 1703 H HZ3 . LYS A 1 109 ? 2.370 205.330 11.196 1.00 81.03 ? 415 LYS A HZ3 1 ATOM 1704 N N . ILE A 1 110 ? 8.000 203.106 8.183 1.00 15.31 ? 416 ILE A N 1 ATOM 1705 C CA . ILE A 1 110 ? 8.041 203.839 6.916 1.00 20.09 ? 416 ILE A CA 1 ATOM 1706 C C . ILE A 1 110 ? 6.789 204.700 6.807 1.00 17.04 ? 416 ILE A C 1 ATOM 1707 O O . ILE A 1 110 ? 5.661 204.193 6.835 1.00 23.68 ? 416 ILE A O 1 ATOM 1708 C CB . ILE A 1 110 ? 8.158 202.893 5.715 1.00 19.87 ? 416 ILE A CB 1 ATOM 1709 C CG1 . ILE A 1 110 ? 9.336 201.939 5.887 1.00 18.35 ? 416 ILE A CG1 1 ATOM 1710 C CG2 . ILE A 1 110 ? 8.350 203.730 4.419 1.00 17.43 ? 416 ILE A CG2 1 ATOM 1711 C CD1 . ILE A 1 110 ? 9.509 200.944 4.756 1.00 19.88 ? 416 ILE A CD1 1 ATOM 1712 H H . ILE A 1 110 ? 7.814 202.270 8.106 1.00 18.37 ? 416 ILE A H 1 ATOM 1713 H HA . ILE A 1 110 ? 8.812 204.426 6.914 1.00 24.11 ? 416 ILE A HA 1 ATOM 1714 H HB . ILE A 1 110 ? 7.341 202.376 5.639 1.00 23.85 ? 416 ILE A HB 1 ATOM 1715 H HG12 . ILE A 1 110 ? 10.151 202.461 5.947 1.00 22.02 ? 416 ILE A HG12 1 ATOM 1716 H HG13 . ILE A 1 110 ? 9.209 201.435 6.706 1.00 22.02 ? 416 ILE A HG13 1 ATOM 1717 H HG21 . ILE A 1 110 ? 8.423 203.128 3.663 1.00 20.91 ? 416 ILE A HG21 1 ATOM 1718 H HG22 . ILE A 1 110 ? 7.583 204.314 4.305 1.00 20.91 ? 416 ILE A HG22 1 ATOM 1719 H HG23 . ILE A 1 110 ? 9.159 204.259 4.502 1.00 20.91 ? 416 ILE A HG23 1 ATOM 1720 H HD11 . ILE A 1 110 ? 10.276 200.381 4.947 1.00 23.86 ? 416 ILE A HD11 1 ATOM 1721 H HD12 . ILE A 1 110 ? 8.708 200.401 4.689 1.00 23.86 ? 416 ILE A HD12 1 ATOM 1722 H HD13 . ILE A 1 110 ? 9.652 201.429 3.929 1.00 23.86 ? 416 ILE A HD13 1 ATOM 1723 N N . ASP A 1 111 ? 6.985 206.008 6.717 1.00 17.36 ? 417 ASP A N 1 ATOM 1724 C CA . ASP A 1 111 ? 5.887 206.939 6.486 1.00 16.99 ? 417 ASP A CA 1 ATOM 1725 C C . ASP A 1 111 ? 5.260 206.671 5.118 1.00 20.59 ? 417 ASP A C 1 ATOM 1726 O O . ASP A 1 111 ? 5.944 206.714 4.091 1.00 16.40 ? 417 ASP A O 1 ATOM 1727 C CB . ASP A 1 111 ? 6.421 208.368 6.568 1.00 21.62 ? 417 ASP A CB 1 ATOM 1728 C CG . ASP A 1 111 ? 5.319 209.424 6.611 1.00 29.75 ? 417 ASP A CG 1 ATOM 1729 O OD1 . ASP A 1 111 ? 4.125 209.079 6.538 1.00 32.77 ? 417 ASP A OD1 1 ATOM 1730 O OD2 . ASP A 1 111 ? 5.668 210.616 6.719 1.00 37.39 ? 417 ASP A OD2 1 ATOM 1731 H H . ASP A 1 111 ? 7.754 206.387 6.788 1.00 20.83 ? 417 ASP A H 1 ATOM 1732 H HA . ASP A 1 111 ? 5.207 206.821 7.169 1.00 20.39 ? 417 ASP A HA 1 ATOM 1733 H HB2 . ASP A 1 111 ? 6.953 208.459 7.374 1.00 25.95 ? 417 ASP A HB2 1 ATOM 1734 H HB3 . ASP A 1 111 ? 6.971 208.543 5.788 1.00 25.95 ? 417 ASP A HB3 1 ATOM 1735 N N . THR A 1 112 ? 3.964 206.375 5.104 1.00 13.07 ? 418 THR A N 1 ATOM 1736 C CA . THR A 1 112 ? 3.278 206.095 3.858 1.00 26.39 ? 418 THR A CA 1 ATOM 1737 C C . THR A 1 112 ? 2.517 207.300 3.308 1.00 27.42 ? 418 THR A C 1 ATOM 1738 O O . THR A 1 112 ? 2.000 207.218 2.193 1.00 16.32 ? 418 THR A O 1 ATOM 1739 C CB . THR A 1 112 ? 2.301 204.930 4.038 1.00 21.14 ? 418 THR A CB 1 ATOM 1740 O OG1 . THR A 1 112 ? 1.221 205.359 4.860 1.00 23.53 ? 418 THR A OG1 1 ATOM 1741 C CG2 . THR A 1 112 ? 2.991 203.709 4.689 1.00 25.70 ? 418 THR A CG2 1 ATOM 1742 H H . THR A 1 112 ? 3.465 206.331 5.803 1.00 15.68 ? 418 THR A H 1 ATOM 1743 H HA . THR A 1 112 ? 3.934 205.832 3.194 1.00 31.67 ? 418 THR A HA 1 ATOM 1744 H HB . THR A 1 112 ? 1.959 204.662 3.172 1.00 25.37 ? 418 THR A HB 1 ATOM 1745 H HG1 . THR A 1 112 ? 1.510 205.601 5.610 1.00 28.23 ? 418 THR A HG1 1 ATOM 1746 H HG21 . THR A 1 112 ? 2.354 202.985 4.793 1.00 30.84 ? 418 THR A HG21 1 ATOM 1747 H HG22 . THR A 1 112 ? 3.724 203.406 4.130 1.00 30.84 ? 418 THR A HG22 1 ATOM 1748 H HG23 . THR A 1 112 ? 3.339 203.951 5.561 1.00 30.84 ? 418 THR A HG23 1 ATOM 1749 N N . THR A 1 113 ? 2.406 208.398 4.068 1.00 21.80 ? 419 THR A N 1 ATOM 1750 C CA . THR A 1 113 ? 1.656 209.564 3.615 1.00 27.87 ? 419 THR A CA 1 ATOM 1751 C C . THR A 1 113 ? 2.520 210.586 2.894 1.00 28.35 ? 419 THR A C 1 ATOM 1752 O O . THR A 1 113 ? 1.994 211.377 2.109 1.00 37.00 ? 419 THR A O 1 ATOM 1753 C CB . THR A 1 113 ? 0.960 210.247 4.799 1.00 30.34 ? 419 THR A CB 1 ATOM 1754 O OG1 . THR A 1 113 ? 1.931 210.840 5.677 1.00 31.02 ? 419 THR A OG1 1 ATOM 1755 C CG2 . THR A 1 113 ? 0.145 209.238 5.563 1.00 32.55 ? 419 THR A CG2 1 ATOM 1756 H H . THR A 1 113 ? 2.759 208.488 4.847 1.00 26.16 ? 419 THR A H 1 ATOM 1757 H HA . THR A 1 113 ? 0.968 209.271 2.997 1.00 33.44 ? 419 THR A HA 1 ATOM 1758 H HB . THR A 1 113 ? 0.362 210.935 4.468 1.00 36.41 ? 419 THR A HB 1 ATOM 1759 H HG1 . THR A 1 113 ? 2.450 210.250 5.973 1.00 37.22 ? 419 THR A HG1 1 ATOM 1760 H HG21 . THR A 1 113 ? -0.296 209.667 6.313 1.00 39.06 ? 419 THR A HG21 1 ATOM 1761 H HG22 . THR A 1 113 ? -0.527 208.847 4.983 1.00 39.06 ? 419 THR A HG22 1 ATOM 1762 H HG23 . THR A 1 113 ? 0.721 208.532 5.898 1.00 39.06 ? 419 THR A HG23 1 ATOM 1763 N N . SER A 1 114 ? 3.823 210.576 3.134 1.00 26.74 ? 420 SER A N 1 ATOM 1764 C CA . SER A 1 114 ? 4.747 211.486 2.494 1.00 25.99 ? 420 SER A CA 1 ATOM 1765 C C . SER A 1 114 ? 5.128 210.971 1.109 1.00 20.79 ? 420 SER A C 1 ATOM 1766 O O . SER A 1 114 ? 4.838 209.835 0.741 1.00 26.64 ? 420 SER A O 1 ATOM 1767 C CB . SER A 1 114 ? 5.999 211.650 3.356 1.00 31.22 ? 420 SER A CB 1 ATOM 1768 O OG . SER A 1 114 ? 6.700 210.410 3.431 1.00 42.76 ? 420 SER A OG 1 ATOM 1769 H H . SER A 1 114 ? 4.203 210.033 3.683 1.00 32.09 ? 420 SER A H 1 ATOM 1770 H HA . SER A 1 114 ? 4.328 212.355 2.394 1.00 31.18 ? 420 SER A HA 1 ATOM 1771 H HB2 . SER A 1 114 ? 6.576 212.319 2.956 1.00 37.47 ? 420 SER A HB2 1 ATOM 1772 H HB3 . SER A 1 114 ? 5.738 211.924 4.249 1.00 37.47 ? 420 SER A HB3 1 ATOM 1773 H HG . SER A 1 114 ? 7.388 210.497 3.904 1.00 51.31 ? 420 SER A HG 1 ATOM 1774 N N . SER A 1 115 ? 5.795 211.834 0.342 1.00 17.54 ? 421 SER A N 1 ATOM 1775 C CA . SER A 1 115 ? 6.399 211.456 -0.925 1.00 25.39 ? 421 SER A CA 1 ATOM 1776 C C . SER A 1 115 ? 7.762 210.854 -0.634 1.00 20.47 ? 421 SER A C 1 ATOM 1777 O O . SER A 1 115 ? 8.629 211.527 -0.061 1.00 17.77 ? 421 SER A O 1 ATOM 1778 C CB . SER A 1 115 ? 6.525 212.672 -1.850 1.00 25.73 ? 421 SER A CB 1 ATOM 1779 O OG . SER A 1 115 ? 5.255 213.110 -2.292 1.00 24.33 ? 421 SER A OG 1 ATOM 1780 H H . SER A 1 115 ? 5.911 212.662 0.543 1.00 21.05 ? 421 SER A H 1 ATOM 1781 H HA . SER A 1 115 ? 5.851 210.787 -1.363 1.00 30.47 ? 421 SER A HA 1 ATOM 1782 H HB2 . SER A 1 115 ? 6.955 213.393 -1.364 1.00 30.88 ? 421 SER A HB2 1 ATOM 1783 H HB3 . SER A 1 115 ? 7.060 212.427 -2.621 1.00 30.88 ? 421 SER A HB3 1 ATOM 1784 H HG . SER A 1 115 ? 4.870 212.495 -2.715 1.00 29.19 ? 421 SER A HG 1 ATOM 1785 N N . SER A 1 116 ? 7.951 209.590 -1.008 1.00 16.75 ? 422 SER A N 1 ATOM 1786 C CA . SER A 1 116 ? 9.141 208.877 -0.570 1.00 20.68 ? 422 SER A CA 1 ATOM 1787 C C . SER A 1 116 ? 9.571 207.842 -1.599 1.00 22.81 ? 422 SER A C 1 ATOM 1788 O O . SER A 1 116 ? 8.806 207.429 -2.475 1.00 24.43 ? 422 SER A O 1 ATOM 1789 C CB . SER A 1 116 ? 8.933 208.184 0.787 1.00 19.50 ? 422 SER A CB 1 ATOM 1790 O OG . SER A 1 116 ? 7.988 207.134 0.682 1.00 26.42 ? 422 SER A OG 1 ATOM 1791 H H . SER A 1 116 ? 7.417 209.134 -1.504 1.00 20.10 ? 422 SER A H 1 ATOM 1792 H HA . SER A 1 116 ? 9.866 209.513 -0.469 1.00 24.82 ? 422 SER A HA 1 ATOM 1793 H HB2 . SER A 1 116 ? 9.779 207.817 1.086 1.00 23.40 ? 422 SER A HB2 1 ATOM 1794 H HB3 . SER A 1 116 ? 8.609 208.836 1.428 1.00 23.40 ? 422 SER A HB3 1 ATOM 1795 H HG . SER A 1 116 ? 7.249 207.438 0.423 1.00 31.71 ? 422 SER A HG 1 ATOM 1796 N N . CYS A 1 117 ? 10.830 207.448 -1.476 1.00 20.11 ? 423 CYS A N 1 ATOM 1797 C CA A CYS A 1 117 ? 11.383 206.385 -2.282 0.66 19.85 ? 423 CYS A CA 1 ATOM 1798 C CA B CYS A 1 117 ? 11.444 206.415 -2.295 0.34 19.92 ? 423 CYS A CA 1 ATOM 1799 C C . CYS A 1 117 ? 12.194 205.459 -1.382 1.00 24.99 ? 423 CYS A C 1 ATOM 1800 O O . CYS A 1 117 ? 12.837 205.897 -0.420 1.00 17.81 ? 423 CYS A O 1 ATOM 1801 C CB A CYS A 1 117 ? 12.222 206.960 -3.426 0.66 22.77 ? 423 CYS A CB 1 ATOM 1802 C CB B CYS A 1 117 ? 12.426 207.000 -3.316 0.34 22.62 ? 423 CYS A CB 1 ATOM 1803 S SG A CYS A 1 117 ? 11.328 208.207 -4.435 0.66 22.38 ? 423 CYS A SG 1 ATOM 1804 S SG B CYS A 1 117 ? 12.193 208.745 -3.717 0.34 22.30 ? 423 CYS A SG 1 ATOM 1805 H H A CYS A 1 117 ? 11.391 207.791 -0.922 0.66 24.13 ? 423 CYS A H 1 ATOM 1806 H H B CYS A 1 117 ? 11.373 207.781 -0.898 0.34 24.13 ? 423 CYS A H 1 ATOM 1807 H HA A CYS A 1 117 ? 10.658 205.870 -2.670 0.66 23.82 ? 423 CYS A HA 1 ATOM 1808 H HA B CYS A 1 117 ? 10.757 205.921 -2.770 0.34 23.90 ? 423 CYS A HA 1 ATOM 1809 H HB2 A CYS A 1 117 ? 13.009 207.388 -3.054 0.66 27.33 ? 423 CYS A HB2 1 ATOM 1810 H HB2 B CYS A 1 117 ? 13.326 206.900 -2.967 0.34 27.15 ? 423 CYS A HB2 1 ATOM 1811 H HB3 A CYS A 1 117 ? 12.487 206.236 -4.015 0.66 27.33 ? 423 CYS A HB3 1 ATOM 1812 H HB3 B CYS A 1 117 ? 12.344 206.499 -4.142 0.34 27.15 ? 423 CYS A HB3 1 ATOM 1813 H HG B CYS A 1 117 ? 11.095 208.898 -4.175 0.34 26.76 ? 423 CYS A HG 1 ATOM 1814 N N . GLN A 1 118 ? 12.119 204.164 -1.676 1.00 20.95 ? 424 GLN A N 1 ATOM 1815 C CA . GLN A 1 118 ? 12.830 203.153 -0.907 1.00 21.51 ? 424 GLN A CA 1 ATOM 1816 C C . GLN A 1 118 ? 13.895 202.541 -1.799 1.00 18.39 ? 424 GLN A C 1 ATOM 1817 O O . GLN A 1 118 ? 13.597 202.061 -2.900 1.00 17.25 ? 424 GLN A O 1 ATOM 1818 C CB . GLN A 1 118 ? 11.874 202.098 -0.354 1.00 21.04 ? 424 GLN A CB 1 ATOM 1819 C CG . GLN A 1 118 ? 10.943 202.661 0.706 1.00 19.29 ? 424 GLN A CG 1 ATOM 1820 C CD . GLN A 1 118 ? 9.787 203.458 0.121 1.00 21.93 ? 424 GLN A CD 1 ATOM 1821 O OE1 . GLN A 1 118 ? 9.041 202.955 -0.704 1.00 21.68 ? 424 GLN A OE1 1 ATOM 1822 N NE2 . GLN A 1 118 ? 9.638 204.705 0.551 1.00 22.95 ? 424 GLN A NE2 1 ATOM 1823 H H . GLN A 1 118 ? 11.656 203.843 -2.326 1.00 25.14 ? 424 GLN A H 1 ATOM 1824 H HA . GLN A 1 118 ? 13.274 203.579 -0.157 1.00 25.82 ? 424 GLN A HA 1 ATOM 1825 H HB2 . GLN A 1 118 ? 11.331 201.751 -1.079 1.00 25.24 ? 424 GLN A HB2 1 ATOM 1826 H HB3 . GLN A 1 118 ? 12.390 201.382 0.049 1.00 25.24 ? 424 GLN A HB3 1 ATOM 1827 H HG2 . GLN A 1 118 ? 10.570 201.927 1.220 1.00 23.15 ? 424 GLN A HG2 1 ATOM 1828 H HG3 . GLN A 1 118 ? 11.447 203.250 1.288 1.00 23.15 ? 424 GLN A HG3 1 ATOM 1829 H HE21 . GLN A 1 118 ? 10.181 205.027 1.134 1.00 27.54 ? 424 GLN A HE21 1 ATOM 1830 H HE22 . GLN A 1 118 ? 8.997 205.191 0.246 1.00 27.54 ? 424 GLN A HE22 1 ATOM 1831 N N . LEU A 1 119 ? 15.137 202.634 -1.347 1.00 18.43 ? 425 LEU A N 1 ATOM 1832 C CA . LEU A 1 119 ? 16.287 202.109 -2.056 1.00 14.19 ? 425 LEU A CA 1 ATOM 1833 C C . LEU A 1 119 ? 16.757 200.838 -1.369 1.00 20.49 ? 425 LEU A C 1 ATOM 1834 O O . LEU A 1 119 ? 16.954 200.824 -0.146 1.00 27.61 ? 425 LEU A O 1 ATOM 1835 C CB . LEU A 1 119 ? 17.413 203.133 -2.080 1.00 21.02 ? 425 LEU A CB 1 ATOM 1836 C CG . LEU A 1 119 ? 18.755 202.672 -2.647 1.00 21.30 ? 425 LEU A CG 1 ATOM 1837 C CD1 . LEU A 1 119 ? 18.586 202.239 -4.095 1.00 27.83 ? 425 LEU A CD1 1 ATOM 1838 C CD2 . LEU A 1 119 ? 19.760 203.810 -2.544 1.00 22.52 ? 425 LEU A CD2 1 ATOM 1839 H H . LEU A 1 119 ? 15.343 203.012 -0.603 1.00 22.12 ? 425 LEU A H 1 ATOM 1840 H HA . LEU A 1 119 ? 16.040 201.896 -2.969 1.00 17.03 ? 425 LEU A HA 1 ATOM 1841 H HB2 . LEU A 1 119 ? 17.121 203.889 -2.613 1.00 25.23 ? 425 LEU A HB2 1 ATOM 1842 H HB3 . LEU A 1 119 ? 17.573 203.427 -1.169 1.00 25.23 ? 425 LEU A HB3 1 ATOM 1843 H HG . LEU A 1 119 ? 19.086 201.918 -2.134 1.00 25.56 ? 425 LEU A HG 1 ATOM 1844 H HD11 . LEU A 1 119 ? 19.445 201.950 -4.440 1.00 33.39 ? 425 LEU A HD11 1 ATOM 1845 H HD12 . LEU A 1 119 ? 17.950 201.507 -4.133 1.00 33.39 ? 425 LEU A HD12 1 ATOM 1846 H HD13 . LEU A 1 119 ? 18.257 202.991 -4.612 1.00 33.39 ? 425 LEU A HD13 1 ATOM 1847 H HD21 . LEU A 1 119 ? 20.610 203.514 -2.905 1.00 27.02 ? 425 LEU A HD21 1 ATOM 1848 H HD22 . LEU A 1 119 ? 19.431 204.568 -3.052 1.00 27.02 ? 425 LEU A HD22 1 ATOM 1849 H HD23 . LEU A 1 119 ? 19.863 204.056 -1.611 1.00 27.02 ? 425 LEU A HD23 1 ATOM 1850 N N . TYR A 1 120 ? 16.909 199.774 -2.147 1.00 18.44 ? 426 TYR A N 1 ATOM 1851 C CA . TYR A 1 120 ? 17.518 198.536 -1.684 1.00 17.36 ? 426 TYR A CA 1 ATOM 1852 C C . TYR A 1 120 ? 18.852 198.388 -2.399 1.00 22.21 ? 426 TYR A C 1 ATOM 1853 O O . TYR A 1 120 ? 18.898 198.405 -3.636 1.00 21.02 ? 426 TYR A O 1 ATOM 1854 C CB . TYR A 1 120 ? 16.601 197.346 -1.951 1.00 19.58 ? 426 TYR A CB 1 ATOM 1855 C CG . TYR A 1 120 ? 15.358 197.382 -1.112 1.00 16.18 ? 426 TYR A CG 1 ATOM 1856 C CD1 . TYR A 1 120 ? 14.236 198.083 -1.528 1.00 15.28 ? 426 TYR A CD1 1 ATOM 1857 C CD2 . TYR A 1 120 ? 15.309 196.726 0.107 1.00 21.14 ? 426 TYR A CD2 1 ATOM 1858 C CE1 . TYR A 1 120 ? 13.101 198.127 -0.769 1.00 18.17 ? 426 TYR A CE1 1 ATOM 1859 C CE2 . TYR A 1 120 ? 14.173 196.766 0.892 1.00 22.40 ? 426 TYR A CE2 1 ATOM 1860 C CZ . TYR A 1 120 ? 13.077 197.463 0.452 1.00 22.54 ? 426 TYR A CZ 1 ATOM 1861 O OH . TYR A 1 120 ? 11.958 197.480 1.236 1.00 23.43 ? 426 TYR A OH 1 ATOM 1862 H H . TYR A 1 120 ? 16.660 199.745 -2.969 1.00 22.13 ? 426 TYR A H 1 ATOM 1863 H HA . TYR A 1 120 ? 17.683 198.592 -0.729 1.00 20.83 ? 426 TYR A HA 1 ATOM 1864 H HB2 . TYR A 1 120 ? 16.336 197.353 -2.884 1.00 23.50 ? 426 TYR A HB2 1 ATOM 1865 H HB3 . TYR A 1 120 ? 17.078 196.526 -1.747 1.00 23.50 ? 426 TYR A HB3 1 ATOM 1866 H HD1 . TYR A 1 120 ? 14.255 198.529 -2.344 1.00 18.34 ? 426 TYR A HD1 1 ATOM 1867 H HD2 . TYR A 1 120 ? 16.054 196.256 0.404 1.00 25.36 ? 426 TYR A HD2 1 ATOM 1868 H HE1 . TYR A 1 120 ? 12.356 198.599 -1.063 1.00 21.81 ? 426 TYR A HE1 1 ATOM 1869 H HE2 . TYR A 1 120 ? 14.149 196.318 1.707 1.00 26.88 ? 426 TYR A HE2 1 ATOM 1870 H HH . TYR A 1 120 ? 12.093 197.039 1.938 1.00 28.12 ? 426 TYR A HH 1 ATOM 1871 N N . TYR A 1 121 ? 19.932 198.307 -1.623 1.00 20.66 ? 427 TYR A N 1 ATOM 1872 C CA . TYR A 1 121 ? 21.284 198.315 -2.163 1.00 19.61 ? 427 TYR A CA 1 ATOM 1873 C C . TYR A 1 121 ? 22.156 197.452 -1.263 1.00 18.98 ? 427 TYR A C 1 ATOM 1874 O O . TYR A 1 121 ? 21.684 196.868 -0.280 1.00 20.39 ? 427 TYR A O 1 ATOM 1875 C CB . TYR A 1 121 ? 21.808 199.760 -2.314 1.00 20.29 ? 427 TYR A CB 1 ATOM 1876 C CG . TYR A 1 121 ? 22.148 200.511 -1.036 1.00 16.45 ? 427 TYR A CG 1 ATOM 1877 C CD1 . TYR A 1 121 ? 21.152 201.020 -0.214 1.00 19.74 ? 427 TYR A CD1 1 ATOM 1878 C CD2 . TYR A 1 121 ? 23.469 200.743 -0.672 1.00 16.13 ? 427 TYR A CD2 1 ATOM 1879 C CE1 . TYR A 1 121 ? 21.460 201.725 0.951 1.00 15.70 ? 427 TYR A CE1 1 ATOM 1880 C CE2 . TYR A 1 121 ? 23.785 201.445 0.480 1.00 19.56 ? 427 TYR A CE2 1 ATOM 1881 C CZ . TYR A 1 121 ? 22.781 201.932 1.293 1.00 18.65 ? 427 TYR A CZ 1 ATOM 1882 O OH . TYR A 1 121 ? 23.103 202.626 2.453 1.00 19.92 ? 427 TYR A OH 1 ATOM 1883 H H . TYR A 1 121 ? 19.904 198.246 -0.766 1.00 24.79 ? 427 TYR A H 1 ATOM 1884 H HA . TYR A 1 121 ? 21.272 197.910 -3.044 1.00 23.54 ? 427 TYR A HA 1 ATOM 1885 H HB2 . TYR A 1 121 ? 22.614 199.733 -2.852 1.00 24.35 ? 427 TYR A HB2 1 ATOM 1886 H HB3 . TYR A 1 121 ? 21.132 200.279 -2.778 1.00 24.35 ? 427 TYR A HB3 1 ATOM 1887 H HD1 . TYR A 1 121 ? 20.261 200.882 -0.440 1.00 23.69 ? 427 TYR A HD1 1 ATOM 1888 H HD2 . TYR A 1 121 ? 24.154 200.419 -1.211 1.00 19.35 ? 427 TYR A HD2 1 ATOM 1889 H HE1 . TYR A 1 121 ? 20.779 202.051 1.495 1.00 18.84 ? 427 TYR A HE1 1 ATOM 1890 H HE2 . TYR A 1 121 ? 24.676 201.580 0.711 1.00 23.47 ? 427 TYR A HE2 1 ATOM 1891 H HH . TYR A 1 121 ? 23.937 202.676 2.535 1.00 23.90 ? 427 TYR A HH 1 ATOM 1892 N N . SER A 1 122 ? 23.430 197.332 -1.628 1.00 19.22 ? 428 SER A N 1 ATOM 1893 C CA . SER A 1 122 ? 24.329 196.481 -0.860 1.00 20.15 ? 428 SER A CA 1 ATOM 1894 C C . SER A 1 122 ? 25.757 196.988 -0.972 1.00 22.52 ? 428 SER A C 1 ATOM 1895 O O . SER A 1 122 ? 26.110 197.754 -1.880 1.00 21.82 ? 428 SER A O 1 ATOM 1896 C CB . SER A 1 122 ? 24.259 195.007 -1.310 1.00 23.96 ? 428 SER A CB 1 ATOM 1897 O OG . SER A 1 122 ? 24.848 194.808 -2.584 1.00 24.48 ? 428 SER A OG 1 ATOM 1898 H H . SER A 1 122 ? 23.792 197.725 -2.302 1.00 23.06 ? 428 SER A H 1 ATOM 1899 H HA . SER A 1 122 ? 24.073 196.518 0.075 1.00 24.18 ? 428 SER A HA 1 ATOM 1900 H HB2 . SER A 1 122 ? 24.729 194.461 -0.661 1.00 28.76 ? 428 SER A HB2 1 ATOM 1901 H HB3 . SER A 1 122 ? 23.328 194.738 -1.352 1.00 28.76 ? 428 SER A HB3 1 ATOM 1902 H HG . SER A 1 122 ? 24.450 195.271 -3.160 1.00 29.37 ? 428 SER A HG 1 ATOM 1903 N N . LEU A 1 123 ? 26.564 196.554 -0.017 1.00 20.77 ? 429 LEU A N 1 ATOM 1904 C CA . LEU A 1 123 ? 27.973 196.888 0.102 1.00 23.88 ? 429 LEU A CA 1 ATOM 1905 C C . LEU A 1 123 ? 28.754 195.598 0.256 1.00 22.33 ? 429 LEU A C 1 ATOM 1906 O O . LEU A 1 123 ? 28.217 194.600 0.744 1.00 27.83 ? 429 LEU A O 1 ATOM 1907 C CB . LEU A 1 123 ? 28.255 197.782 1.317 1.00 18.08 ? 429 LEU A CB 1 ATOM 1908 C CG . LEU A 1 123 ? 27.988 199.266 1.203 1.00 27.29 ? 429 LEU A CG 1 ATOM 1909 C CD1 . LEU A 1 123 ? 28.189 199.925 2.562 1.00 28.04 ? 429 LEU A CD1 1 ATOM 1910 C CD2 . LEU A 1 123 ? 28.909 199.894 0.155 1.00 29.19 ? 429 LEU A CD2 1 ATOM 1911 H H . LEU A 1 123 ? 26.298 196.031 0.612 1.00 24.93 ? 429 LEU A H 1 ATOM 1912 H HA . LEU A 1 123 ? 28.274 197.344 -0.699 1.00 28.65 ? 429 LEU A HA 1 ATOM 1913 H HB2 . LEU A 1 123 ? 27.715 197.457 2.055 1.00 21.69 ? 429 LEU A HB2 1 ATOM 1914 H HB3 . LEU A 1 123 ? 29.192 197.683 1.546 1.00 21.69 ? 429 LEU A HB3 1 ATOM 1915 H HG . LEU A 1 123 ? 27.069 199.408 0.928 1.00 32.75 ? 429 LEU A HG 1 ATOM 1916 H HD11 . LEU A 1 123 ? 28.016 200.876 2.480 1.00 33.65 ? 429 LEU A HD11 1 ATOM 1917 H HD12 . LEU A 1 123 ? 27.573 199.529 3.198 1.00 33.65 ? 429 LEU A HD12 1 ATOM 1918 H HD13 . LEU A 1 123 ? 29.103 199.778 2.851 1.00 33.65 ? 429 LEU A HD13 1 ATOM 1919 H HD21 . LEU A 1 123 ? 28.721 200.844 0.099 1.00 35.03 ? 429 LEU A HD21 1 ATOM 1920 H HD22 . LEU A 1 123 ? 29.831 199.754 0.421 1.00 35.03 ? 429 LEU A HD22 1 ATOM 1921 H HD23 . LEU A 1 123 ? 28.744 199.472 -0.703 1.00 35.03 ? 429 LEU A HD23 1 ATOM 1922 N N . PRO A 1 124 ? 30.029 195.586 -0.130 1.00 27.43 ? 430 PRO A N 1 ATOM 1923 C CA . PRO A 1 124 ? 30.812 194.352 0.005 1.00 33.13 ? 430 PRO A CA 1 ATOM 1924 C C . PRO A 1 124 ? 30.968 194.000 1.478 1.00 31.53 ? 430 PRO A C 1 ATOM 1925 O O . PRO A 1 124 ? 31.312 194.852 2.303 1.00 24.24 ? 430 PRO A O 1 ATOM 1926 C CB . PRO A 1 124 ? 32.158 194.698 -0.647 1.00 31.34 ? 430 PRO A CB 1 ATOM 1927 C CG . PRO A 1 124 ? 31.981 196.039 -1.262 1.00 34.70 ? 430 PRO A CG 1 ATOM 1928 C CD . PRO A 1 124 ? 30.877 196.715 -0.530 1.00 29.75 ? 430 PRO A CD 1 ATOM 1929 H HA . PRO A 1 124 ? 30.392 193.618 -0.470 1.00 39.75 ? 430 PRO A HA 1 ATOM 1930 H HB2 . PRO A 1 124 ? 32.851 194.723 0.032 1.00 37.61 ? 430 PRO A HB2 1 ATOM 1931 H HB3 . PRO A 1 124 ? 32.369 194.037 -1.325 1.00 37.61 ? 430 PRO A HB3 1 ATOM 1932 H HG2 . PRO A 1 124 ? 32.804 196.544 -1.173 1.00 41.64 ? 430 PRO A HG2 1 ATOM 1933 H HG3 . PRO A 1 124 ? 31.749 195.934 -2.198 1.00 41.64 ? 430 PRO A HG3 1 ATOM 1934 H HD2 . PRO A 1 124 ? 31.219 197.177 0.251 1.00 35.70 ? 430 PRO A HD2 1 ATOM 1935 H HD3 . PRO A 1 124 ? 30.393 197.314 -1.120 1.00 35.70 ? 430 PRO A HD3 1 ATOM 1936 N N . ALA A 1 125 ? 30.691 192.738 1.804 1.00 27.18 ? 431 ALA A N 1 ATOM 1937 C CA . ALA A 1 125 ? 30.615 192.340 3.206 1.00 27.43 ? 431 ALA A CA 1 ATOM 1938 C C . ALA A 1 125 ? 31.944 192.549 3.919 1.00 26.21 ? 431 ALA A C 1 ATOM 1939 O O . ALA A 1 125 ? 31.971 193.006 5.064 1.00 23.83 ? 431 ALA A O 1 ATOM 1940 C CB . ALA A 1 125 ? 30.176 190.876 3.314 1.00 25.26 ? 431 ALA A CB 1 ATOM 1941 H H . ALA A 1 125 ? 30.546 192.104 1.242 1.00 32.61 ? 431 ALA A H 1 ATOM 1942 H HA . ALA A 1 125 ? 29.948 192.885 3.652 1.00 32.92 ? 431 ALA A HA 1 ATOM 1943 H HB1 . ALA A 1 125 ? 30.131 190.629 4.251 1.00 30.31 ? 431 ALA A HB1 1 ATOM 1944 H HB2 . ALA A 1 125 ? 29.304 190.777 2.902 1.00 30.31 ? 431 ALA A HB2 1 ATOM 1945 H HB3 . ALA A 1 125 ? 30.824 190.319 2.855 1.00 30.31 ? 431 ALA A HB3 1 ATOM 1946 N N . ILE A 1 126 ? 33.059 192.250 3.244 1.00 30.65 ? 432 ILE A N 1 ATOM 1947 C CA A ILE A 1 126 ? 34.369 192.283 3.883 0.38 33.29 ? 432 ILE A CA 1 ATOM 1948 C CA B ILE A 1 126 ? 34.369 192.282 3.884 0.62 33.27 ? 432 ILE A CA 1 ATOM 1949 C C . ILE A 1 126 ? 34.723 193.674 4.385 1.00 34.46 ? 432 ILE A C 1 ATOM 1950 O O . ILE A 1 126 ? 35.571 193.811 5.270 1.00 32.76 ? 432 ILE A O 1 ATOM 1951 C CB A ILE A 1 126 ? 35.454 191.766 2.911 0.38 37.73 ? 432 ILE A CB 1 ATOM 1952 C CB B ILE A 1 126 ? 35.450 191.763 2.910 0.62 37.75 ? 432 ILE A CB 1 ATOM 1953 C CG1 A ILE A 1 126 ? 35.475 192.603 1.626 0.38 39.32 ? 432 ILE A CG1 1 ATOM 1954 C CG1 B ILE A 1 126 ? 36.722 191.380 3.671 0.62 40.52 ? 432 ILE A CG1 1 ATOM 1955 C CG2 A ILE A 1 126 ? 35.231 190.284 2.611 0.38 35.79 ? 432 ILE A CG2 1 ATOM 1956 C CG2 B ILE A 1 126 ? 35.770 192.809 1.851 0.62 38.88 ? 432 ILE A CG2 1 ATOM 1957 C CD1 A ILE A 1 126 ? 36.568 192.217 0.636 0.38 42.48 ? 432 ILE A CD1 1 ATOM 1958 C CD1 B ILE A 1 126 ? 37.756 190.657 2.821 0.62 40.94 ? 432 ILE A CD1 1 ATOM 1959 H H . ILE A 1 126 ? 33.079 192.026 2.414 1.00 36.78 ? 432 ILE A H 1 ATOM 1960 H HA A ILE A 1 126 ? 34.354 191.689 4.650 0.38 39.95 ? 432 ILE A HA 1 ATOM 1961 H HA B ILE A 1 126 ? 34.354 191.689 4.651 0.62 39.92 ? 432 ILE A HA 1 ATOM 1962 H HB A ILE A 1 126 ? 36.317 191.859 3.345 0.38 45.28 ? 432 ILE A HB 1 ATOM 1963 H HB B ILE A 1 126 ? 35.108 190.972 2.466 0.62 45.30 ? 432 ILE A HB 1 ATOM 1964 H HG12 A ILE A 1 126 ? 34.621 192.501 1.176 0.38 47.19 ? 432 ILE A HG12 1 ATOM 1965 H HG12 B ILE A 1 126 ? 37.135 192.187 4.017 0.62 48.63 ? 432 ILE A HG12 1 ATOM 1966 H HG13 A ILE A 1 126 ? 35.609 193.533 1.864 0.38 47.19 ? 432 ILE A HG13 1 ATOM 1967 H HG13 B ILE A 1 126 ? 36.482 190.794 4.406 0.62 48.63 ? 432 ILE A HG13 1 ATOM 1968 H HG21 A ILE A 1 126 ? 35.920 189.979 2.001 0.38 42.94 ? 432 ILE A HG21 1 ATOM 1969 H HG21 B ILE A 1 126 ? 36.450 192.457 1.256 0.62 46.65 ? 432 ILE A HG21 1 ATOM 1970 H HG22 A ILE A 1 126 ? 35.278 189.784 3.440 0.38 42.94 ? 432 ILE A HG22 1 ATOM 1971 H HG22 B ILE A 1 126 ? 34.963 193.009 1.352 0.62 46.65 ? 432 ILE A HG22 1 ATOM 1972 H HG23 A ILE A 1 126 ? 34.357 190.173 2.205 0.38 42.94 ? 432 ILE A HG23 1 ATOM 1973 H HG23 B ILE A 1 126 ? 36.096 193.611 2.289 0.62 46.65 ? 432 ILE A HG23 1 ATOM 1974 H HD11 A ILE A 1 126 ? 36.507 192.793 -0.142 0.38 50.97 ? 432 ILE A HD11 1 ATOM 1975 H HD11 B ILE A 1 126 ? 38.528 190.449 3.371 0.62 49.13 ? 432 ILE A HD11 1 ATOM 1976 H HD12 A ILE A 1 126 ? 37.432 192.326 1.062 0.38 50.97 ? 432 ILE A HD12 1 ATOM 1977 H HD12 B ILE A 1 126 ? 37.365 189.839 2.476 0.62 49.13 ? 432 ILE A HD12 1 ATOM 1978 H HD13 A ILE A 1 126 ? 36.443 191.291 0.373 0.38 50.97 ? 432 ILE A HD13 1 ATOM 1979 H HD13 B ILE A 1 126 ? 38.019 191.234 2.086 0.62 49.13 ? 432 ILE A HD13 1 ATOM 1980 N N . ASN A 1 127 ? 34.102 194.714 3.836 1.00 34.57 ? 433 ASN A N 1 ATOM 1981 C CA . ASN A 1 127 ? 34.394 196.083 4.236 1.00 32.42 ? 433 ASN A CA 1 ATOM 1982 C C . ASN A 1 127 ? 33.353 196.661 5.183 1.00 32.72 ? 433 ASN A C 1 ATOM 1983 O O . ASN A 1 127 ? 33.554 197.765 5.696 1.00 33.56 ? 433 ASN A O 1 ATOM 1984 C CB . ASN A 1 127 ? 34.522 196.973 2.998 1.00 35.35 ? 433 ASN A CB 1 ATOM 1985 C CG . ASN A 1 127 ? 35.566 196.457 2.027 1.00 43.78 ? 433 ASN A CG 1 ATOM 1986 O OD1 . ASN A 1 127 ? 35.230 195.916 0.970 1.00 46.01 ? 433 ASN A OD1 1 ATOM 1987 N ND2 . ASN A 1 127 ? 36.844 196.613 2.387 1.00 50.16 ? 433 ASN A ND2 1 ATOM 1988 H H . ASN A 1 127 ? 33.501 194.651 3.223 1.00 41.48 ? 433 ASN A H 1 ATOM 1989 H HA . ASN A 1 127 ? 35.248 196.095 4.696 1.00 38.91 ? 433 ASN A HA 1 ATOM 1990 H HB2 . ASN A 1 127 ? 33.669 197.001 2.537 1.00 42.41 ? 433 ASN A HB2 1 ATOM 1991 H HB3 . ASN A 1 127 ? 34.782 197.866 3.273 1.00 42.41 ? 433 ASN A HB3 1 ATOM 1992 H HD21 . ASN A 1 127 ? 37.026 196.987 3.139 1.00 60.20 ? 433 ASN A HD21 1 ATOM 1993 N N . VAL A 1 128 ? 32.268 195.937 5.452 1.00 24.86 ? 434 VAL A N 1 ATOM 1994 C CA . VAL A 1 128 ? 31.169 196.444 6.264 1.00 25.79 ? 434 VAL A CA 1 ATOM 1995 C C . VAL A 1 128 ? 31.334 195.985 7.711 1.00 26.11 ? 434 VAL A C 1 ATOM 1996 O O . VAL A 1 128 ? 31.576 194.805 7.981 1.00 26.53 ? 434 VAL A O 1 ATOM 1997 C CB . VAL A 1 128 ? 29.814 195.997 5.692 1.00 22.00 ? 434 VAL A CB 1 ATOM 1998 C CG1 . VAL A 1 128 ? 28.670 196.311 6.662 1.00 23.48 ? 434 VAL A CG1 1 ATOM 1999 C CG2 . VAL A 1 128 ? 29.565 196.693 4.382 1.00 23.56 ? 434 VAL A CG2 1 ATOM 2000 H H . VAL A 1 128 ? 32.144 195.135 5.168 1.00 29.84 ? 434 VAL A H 1 ATOM 2001 H HA . VAL A 1 128 ? 31.191 197.414 6.254 1.00 30.95 ? 434 VAL A HA 1 ATOM 2002 H HB . VAL A 1 128 ? 29.829 195.040 5.534 1.00 26.40 ? 434 VAL A HB 1 ATOM 2003 H HG11 . VAL A 1 128 ? 27.833 196.016 6.269 1.00 28.17 ? 434 VAL A HG11 1 ATOM 2004 H HG12 . VAL A 1 128 ? 28.826 195.842 7.497 1.00 28.17 ? 434 VAL A HG12 1 ATOM 2005 H HG13 . VAL A 1 128 ? 28.643 197.268 6.819 1.00 28.17 ? 434 VAL A HG13 1 ATOM 2006 H HG21 . VAL A 1 128 ? 28.708 196.404 4.029 1.00 28.27 ? 434 VAL A HG21 1 ATOM 2007 H HG22 . VAL A 1 128 ? 29.556 197.651 4.530 1.00 28.27 ? 434 VAL A HG22 1 ATOM 2008 H HG23 . VAL A 1 128 ? 30.273 196.460 3.761 1.00 28.27 ? 434 VAL A HG23 1 ATOM 2009 N N . THR A 1 129 ? 31.200 196.925 8.635 1.00 26.99 ? 435 THR A N 1 ATOM 2010 C CA . THR A 1 129 ? 31.073 196.652 10.063 1.00 29.17 ? 435 THR A CA 1 ATOM 2011 C C . THR A 1 129 ? 29.712 197.163 10.505 1.00 20.35 ? 435 THR A C 1 ATOM 2012 O O . THR A 1 129 ? 29.390 198.337 10.291 1.00 20.91 ? 435 THR A O 1 ATOM 2013 C CB . THR A 1 129 ? 32.180 197.343 10.866 1.00 31.05 ? 435 THR A CB 1 ATOM 2014 O OG1 . THR A 1 129 ? 33.465 196.965 10.354 1.00 40.86 ? 435 THR A OG1 1 ATOM 2015 C CG2 . THR A 1 129 ? 32.092 196.961 12.337 1.00 34.45 ? 435 THR A CG2 1 ATOM 2016 H H . THR A 1 129 ? 31.178 197.765 8.452 1.00 32.38 ? 435 THR A H 1 ATOM 2017 H HA . THR A 1 129 ? 31.118 195.696 10.223 1.00 35.01 ? 435 THR A HA 1 ATOM 2018 H HB . THR A 1 129 ? 32.076 198.305 10.794 1.00 37.26 ? 435 THR A HB 1 ATOM 2019 H HG1 . THR A 1 129 ? 33.531 197.191 9.548 1.00 49.03 ? 435 THR A HG1 1 ATOM 2020 H HG21 . THR A 1 129 ? 32.796 197.403 12.837 1.00 41.34 ? 435 THR A HG21 1 ATOM 2021 H HG22 . THR A 1 129 ? 31.233 197.228 12.698 1.00 41.34 ? 435 THR A HG22 1 ATOM 2022 H HG23 . THR A 1 129 ? 32.191 196.001 12.436 1.00 41.34 ? 435 THR A HG23 1 ATOM 2023 N N . ILE A 1 130 ? 28.917 196.301 11.110 1.00 20.59 ? 436 ILE A N 1 ATOM 2024 C CA . ILE A 1 130 ? 27.602 196.722 11.577 1.00 20.62 ? 436 ILE A CA 1 ATOM 2025 C C . ILE A 1 130 ? 27.749 197.464 12.897 1.00 24.76 ? 436 ILE A C 1 ATOM 2026 O O . ILE A 1 130 ? 28.474 197.031 13.802 1.00 26.64 ? 436 ILE A O 1 ATOM 2027 C CB . ILE A 1 130 ? 26.659 195.519 11.725 1.00 23.94 ? 436 ILE A CB 1 ATOM 2028 C CG1 . ILE A 1 130 ? 26.468 194.816 10.373 1.00 25.18 ? 436 ILE A CG1 1 ATOM 2029 C CG2 . ILE A 1 130 ? 25.326 195.962 12.342 1.00 18.52 ? 436 ILE A CG2 1 ATOM 2030 C CD1 . ILE A 1 130 ? 25.761 195.623 9.322 1.00 17.24 ? 436 ILE A CD1 1 ATOM 2031 H H . ILE A 1 130 ? 29.107 195.477 11.263 1.00 24.70 ? 436 ILE A H 1 ATOM 2032 H HA . ILE A 1 130 ? 27.215 197.332 10.930 1.00 24.75 ? 436 ILE A HA 1 ATOM 2033 H HB . ILE A 1 130 ? 27.074 194.888 12.333 1.00 28.72 ? 436 ILE A HB 1 ATOM 2034 H HG12 . ILE A 1 130 ? 27.342 194.583 10.022 1.00 30.21 ? 436 ILE A HG12 1 ATOM 2035 H HG13 . ILE A 1 130 ? 25.950 194.009 10.517 1.00 30.21 ? 436 ILE A HG13 1 ATOM 2036 H HG21 . ILE A 1 130 ? 24.746 195.189 12.426 1.00 22.23 ? 436 ILE A HG21 1 ATOM 2037 H HG22 . ILE A 1 130 ? 25.495 196.346 13.216 1.00 22.23 ? 436 ILE A HG22 1 ATOM 2038 H HG23 . ILE A 1 130 ? 24.915 196.623 11.763 1.00 22.23 ? 436 ILE A HG23 1 ATOM 2039 H HD11 . ILE A 1 130 ? 25.691 195.094 8.513 1.00 20.69 ? 436 ILE A HD11 1 ATOM 2040 H HD12 . ILE A 1 130 ? 24.876 195.854 9.645 1.00 20.69 ? 436 ILE A HD12 1 ATOM 2041 H HD13 . ILE A 1 130 ? 26.271 196.430 9.148 1.00 20.69 ? 436 ILE A HD13 1 ATOM 2042 N N . ASN A 1 131 ? 27.041 198.582 13.006 1.00 20.74 ? 437 ASN A N 1 ATOM 2043 C CA . ASN A 1 131 ? 26.949 199.358 14.235 1.00 19.11 ? 437 ASN A CA 1 ATOM 2044 C C . ASN A 1 131 ? 25.595 199.059 14.867 1.00 18.70 ? 437 ASN A C 1 ATOM 2045 O O . ASN A 1 131 ? 24.569 199.600 14.445 1.00 15.85 ? 437 ASN A O 1 ATOM 2046 C CB . ASN A 1 131 ? 27.112 200.847 13.955 1.00 26.23 ? 437 ASN A CB 1 ATOM 2047 C CG . ASN A 1 131 ? 27.126 201.692 15.245 1.00 23.34 ? 437 ASN A CG 1 ATOM 2048 O OD1 . ASN A 1 131 ? 27.130 201.155 16.340 1.00 21.45 ? 437 ASN A OD1 1 ATOM 2049 N ND2 . ASN A 1 131 ? 27.126 203.011 15.100 1.00 29.75 ? 437 ASN A ND2 1 ATOM 2050 H H . ASN A 1 131 ? 26.590 198.921 12.358 1.00 24.89 ? 437 ASN A H 1 ATOM 2051 H HA . ASN A 1 131 ? 27.647 199.081 14.850 1.00 22.93 ? 437 ASN A HA 1 ATOM 2052 H HB2 . ASN A 1 131 ? 27.952 200.992 13.491 1.00 31.48 ? 437 ASN A HB2 1 ATOM 2053 H HB3 . ASN A 1 131 ? 26.372 201.149 13.406 1.00 31.48 ? 437 ASN A HB3 1 ATOM 2054 H HD21 . ASN A 1 131 ? 27.133 203.519 15.794 1.00 35.70 ? 437 ASN A HD21 1 ATOM 2055 H HD22 . ASN A 1 131 ? 27.118 203.357 14.313 1.00 35.70 ? 437 ASN A HD22 1 ATOM 2056 N N . ASN A 1 132 ? 25.598 198.177 15.868 1.00 16.17 ? 438 ASN A N 1 ATOM 2057 C CA . ASN A 1 132 ? 24.419 197.901 16.681 1.00 18.18 ? 438 ASN A CA 1 ATOM 2058 C C . ASN A 1 132 ? 24.492 198.776 17.929 1.00 21.95 ? 438 ASN A C 1 ATOM 2059 O O . ASN A 1 132 ? 25.447 198.680 18.698 1.00 17.75 ? 438 ASN A O 1 ATOM 2060 C CB . ASN A 1 132 ? 24.344 196.422 17.058 1.00 17.41 ? 438 ASN A CB 1 ATOM 2061 C CG . ASN A 1 132 ? 24.173 195.518 15.846 1.00 19.25 ? 438 ASN A CG 1 ATOM 2062 O OD1 . ASN A 1 132 ? 23.176 195.603 15.131 1.00 18.33 ? 438 ASN A OD1 1 ATOM 2063 N ND2 . ASN A 1 132 ? 25.130 194.632 15.631 1.00 17.00 ? 438 ASN A ND2 1 ATOM 2064 H H . ASN A 1 132 ? 26.288 197.717 16.098 1.00 19.40 ? 438 ASN A H 1 ATOM 2065 H HA . ASN A 1 132 ? 23.619 198.135 16.185 1.00 21.82 ? 438 ASN A HA 1 ATOM 2066 H HB2 . ASN A 1 132 ? 25.164 196.168 17.509 1.00 20.89 ? 438 ASN A HB2 1 ATOM 2067 H HB3 . ASN A 1 132 ? 23.585 196.283 17.646 1.00 20.89 ? 438 ASN A HB3 1 ATOM 2068 H HD21 . ASN A 1 132 ? 25.079 194.098 14.958 1.00 20.40 ? 438 ASN A HD21 1 ATOM 2069 H HD22 . ASN A 1 132 ? 25.803 194.589 16.164 1.00 20.40 ? 438 ASN A HD22 1 ATOM 2070 N N . TYR A 1 133 ? 23.510 199.660 18.099 1.00 22.97 ? 439 TYR A N 1 ATOM 2071 C CA . TYR A 1 133 ? 23.526 200.625 19.185 1.00 17.43 ? 439 TYR A CA 1 ATOM 2072 C C . TYR A 1 133 ? 22.121 200.729 19.745 1.00 21.95 ? 439 TYR A C 1 ATOM 2073 O O . TYR A 1 133 ? 21.167 200.944 18.987 1.00 18.38 ? 439 TYR A O 1 ATOM 2074 C CB . TYR A 1 133 ? 24.021 201.998 18.703 1.00 23.29 ? 439 TYR A CB 1 ATOM 2075 C CG . TYR A 1 133 ? 23.920 203.098 19.750 1.00 23.02 ? 439 TYR A CG 1 ATOM 2076 C CD1 . TYR A 1 133 ? 24.927 203.297 20.678 1.00 24.46 ? 439 TYR A CD1 1 ATOM 2077 C CD2 . TYR A 1 133 ? 22.813 203.930 19.801 1.00 21.14 ? 439 TYR A CD2 1 ATOM 2078 C CE1 . TYR A 1 133 ? 24.836 204.304 21.643 1.00 28.64 ? 439 TYR A CE1 1 ATOM 2079 C CE2 . TYR A 1 133 ? 22.707 204.933 20.752 1.00 25.47 ? 439 TYR A CE2 1 ATOM 2080 C CZ . TYR A 1 133 ? 23.724 205.117 21.675 1.00 28.80 ? 439 TYR A CZ 1 ATOM 2081 O OH . TYR A 1 133 ? 23.627 206.109 22.632 1.00 31.15 ? 439 TYR A OH 1 ATOM 2082 H H . TYR A 1 133 ? 22.819 199.718 17.591 1.00 27.56 ? 439 TYR A H 1 ATOM 2083 H HA . TYR A 1 133 ? 24.117 200.313 19.888 1.00 20.92 ? 439 TYR A HA 1 ATOM 2084 H HB2 . TYR A 1 133 ? 24.952 201.921 18.445 1.00 27.95 ? 439 TYR A HB2 1 ATOM 2085 H HB3 . TYR A 1 133 ? 23.490 202.270 17.938 1.00 27.95 ? 439 TYR A HB3 1 ATOM 2086 H HD1 . TYR A 1 133 ? 25.678 202.749 20.660 1.00 29.35 ? 439 TYR A HD1 1 ATOM 2087 H HD2 . TYR A 1 133 ? 22.125 203.811 19.186 1.00 25.36 ? 439 TYR A HD2 1 ATOM 2088 H HE1 . TYR A 1 133 ? 25.520 204.422 22.261 1.00 34.37 ? 439 TYR A HE1 1 ATOM 2089 H HE2 . TYR A 1 133 ? 21.954 205.480 20.772 1.00 30.56 ? 439 TYR A HE2 1 ATOM 2090 H HH . TYR A 1 133 ? 22.904 206.527 22.539 1.00 37.38 ? 439 TYR A HH 1 ATOM 2091 N N . ASN A 1 134 ? 22.004 200.573 21.076 1.00 18.39 ? 440 ASN A N 1 ATOM 2092 C CA . ASN A 1 134 ? 20.726 200.646 21.779 1.00 18.71 ? 440 ASN A CA 1 ATOM 2093 C C . ASN A 1 134 ? 20.359 202.109 21.983 1.00 20.99 ? 440 ASN A C 1 ATOM 2094 O O . ASN A 1 134 ? 21.037 202.817 22.734 1.00 20.93 ? 440 ASN A O 1 ATOM 2095 C CB . ASN A 1 134 ? 20.776 199.908 23.129 1.00 16.70 ? 440 ASN A CB 1 ATOM 2096 C CG . ASN A 1 134 ? 19.426 199.865 23.810 1.00 18.63 ? 440 ASN A CG 1 ATOM 2097 O OD1 . ASN A 1 134 ? 18.573 200.678 23.500 1.00 20.80 ? 440 ASN A OD1 1 ATOM 2098 N ND2 . ASN A 1 134 ? 19.216 198.904 24.743 1.00 17.07 ? 440 ASN A ND2 1 ATOM 2099 H H . ASN A 1 134 ? 22.671 200.421 21.598 1.00 22.07 ? 440 ASN A H 1 ATOM 2100 H HA . ASN A 1 134 ? 20.038 200.234 21.233 1.00 22.46 ? 440 ASN A HA 1 ATOM 2101 H HB2 . ASN A 1 134 ? 21.069 198.995 22.981 1.00 20.04 ? 440 ASN A HB2 1 ATOM 2102 H HB3 . ASN A 1 134 ? 21.396 200.366 23.718 1.00 20.04 ? 440 ASN A HB3 1 ATOM 2103 H HD21 . ASN A 1 134 ? 18.459 198.855 25.146 1.00 20.48 ? 440 ASN A HD21 1 ATOM 2104 H HD22 . ASN A 1 134 ? 19.841 198.344 24.931 1.00 20.48 ? 440 ASN A HD22 1 ATOM 2105 N N . PRO A 1 135 ? 19.283 202.587 21.355 1.00 22.17 ? 441 PRO A N 1 ATOM 2106 C CA . PRO A 1 135 ? 18.950 204.012 21.415 1.00 20.92 ? 441 PRO A CA 1 ATOM 2107 C C . PRO A 1 135 ? 18.180 204.445 22.650 1.00 21.83 ? 441 PRO A C 1 ATOM 2108 O O . PRO A 1 135 ? 17.866 205.636 22.760 1.00 23.52 ? 441 PRO A O 1 ATOM 2109 C CB . PRO A 1 135 ? 18.078 204.191 20.172 1.00 22.81 ? 441 PRO A CB 1 ATOM 2110 C CG . PRO A 1 135 ? 17.327 202.903 20.098 1.00 20.02 ? 441 PRO A CG 1 ATOM 2111 C CD . PRO A 1 135 ? 18.315 201.844 20.528 1.00 21.17 ? 441 PRO A CD 1 ATOM 2112 H HA . PRO A 1 135 ? 19.751 204.552 21.327 1.00 25.10 ? 441 PRO A HA 1 ATOM 2113 H HB2 . PRO A 1 135 ? 17.474 204.941 20.294 1.00 27.37 ? 441 PRO A HB2 1 ATOM 2114 H HB3 . PRO A 1 135 ? 18.636 204.315 19.388 1.00 27.37 ? 441 PRO A HB3 1 ATOM 2115 H HG2 . PRO A 1 135 ? 16.569 202.931 20.704 1.00 24.02 ? 441 PRO A HG2 1 ATOM 2116 H HG3 . PRO A 1 135 ? 17.032 202.747 19.187 1.00 24.02 ? 441 PRO A HG3 1 ATOM 2117 H HD2 . PRO A 1 135 ? 17.872 201.163 21.058 1.00 25.40 ? 441 PRO A HD2 1 ATOM 2118 H HD3 . PRO A 1 135 ? 18.757 201.461 19.754 1.00 25.40 ? 441 PRO A HD3 1 ATOM 2119 N N . SER A 1 136 ? 17.831 203.524 23.543 1.00 19.40 ? 442 SER A N 1 ATOM 2120 C CA . SER A 1 136 ? 16.951 203.810 24.674 1.00 21.91 ? 442 SER A CA 1 ATOM 2121 C C . SER A 1 136 ? 17.767 204.344 25.847 1.00 21.71 ? 442 SER A C 1 ATOM 2122 O O . SER A 1 136 ? 18.608 203.621 26.402 1.00 20.86 ? 442 SER A O 1 ATOM 2123 C CB . SER A 1 136 ? 16.198 202.545 25.099 1.00 23.90 ? 442 SER A CB 1 ATOM 2124 O OG . SER A 1 136 ? 15.619 202.689 26.393 1.00 16.47 ? 442 SER A OG 1 ATOM 2125 H H . SER A 1 136 ? 18.097 202.706 23.515 1.00 23.28 ? 442 SER A H 1 ATOM 2126 H HA . SER A 1 136 ? 16.302 204.484 24.418 1.00 26.29 ? 442 SER A HA 1 ATOM 2127 H HB2 . SER A 1 136 ? 15.492 202.370 24.457 1.00 28.68 ? 442 SER A HB2 1 ATOM 2128 H HB3 . SER A 1 136 ? 16.820 201.800 25.115 1.00 28.68 ? 442 SER A HB3 1 ATOM 2129 H HG . SER A 1 136 ? 15.075 203.329 26.395 1.00 19.76 ? 442 SER A HG 1 ATOM 2130 N N . SER A 1 137 ? 17.489 205.584 26.254 1.00 17.54 ? 443 SER A N 1 ATOM 2131 C CA . SER A 1 137 ? 18.224 206.162 27.381 1.00 21.93 ? 443 SER A CA 1 ATOM 2132 C C . SER A 1 137 ? 17.931 205.421 28.679 1.00 18.45 ? 443 SER A C 1 ATOM 2133 O O . SER A 1 137 ? 18.846 205.165 29.466 1.00 21.46 ? 443 SER A O 1 ATOM 2134 C CB . SER A 1 137 ? 17.900 207.654 27.547 1.00 23.98 ? 443 SER A CB 1 ATOM 2135 O OG . SER A 1 137 ? 16.558 207.835 27.935 1.00 29.53 ? 443 SER A OG 1 ATOM 2136 H H . SER A 1 137 ? 16.896 206.100 25.905 1.00 21.05 ? 443 SER A H 1 ATOM 2137 H HA . SER A 1 137 ? 19.175 206.084 27.205 1.00 26.32 ? 443 SER A HA 1 ATOM 2138 H HB2 . SER A 1 137 ? 18.480 208.030 28.228 1.00 28.77 ? 443 SER A HB2 1 ATOM 2139 H HB3 . SER A 1 137 ? 18.048 208.105 26.700 1.00 28.77 ? 443 SER A HB3 1 ATOM 2140 H HG . SER A 1 137 ? 16.044 207.514 27.354 1.00 35.44 ? 443 SER A HG 1 ATOM 2141 N N . TRP A 1 138 ? 16.673 205.050 28.918 1.00 17.90 ? 444 TRP A N 1 ATOM 2142 C CA . TRP A 1 138 ? 16.365 204.359 30.163 1.00 22.32 ? 444 TRP A CA 1 ATOM 2143 C C . TRP A 1 138 ? 17.042 202.992 30.233 1.00 19.30 ? 444 TRP A C 1 ATOM 2144 O O . TRP A 1 138 ? 17.629 202.663 31.267 1.00 18.23 ? 444 TRP A O 1 ATOM 2145 C CB . TRP A 1 138 ? 14.850 204.290 30.392 1.00 19.44 ? 444 TRP A CB 1 ATOM 2146 C CG . TRP A 1 138 ? 14.005 203.237 29.704 1.00 19.30 ? 444 TRP A CG 1 ATOM 2147 C CD1 . TRP A 1 138 ? 13.185 203.427 28.641 1.00 15.00 ? 444 TRP A CD1 1 ATOM 2148 C CD2 . TRP A 1 138 ? 13.822 201.865 30.110 1.00 14.02 ? 444 TRP A CD2 1 ATOM 2149 N NE1 . TRP A 1 138 ? 12.526 202.261 28.332 1.00 17.47 ? 444 TRP A NE1 1 ATOM 2150 C CE2 . TRP A 1 138 ? 12.896 201.290 29.220 1.00 15.14 ? 444 TRP A CE2 1 ATOM 2151 C CE3 . TRP A 1 138 ? 14.357 201.075 31.132 1.00 14.62 ? 444 TRP A CE3 1 ATOM 2152 C CZ2 . TRP A 1 138 ? 12.499 199.962 29.311 1.00 15.48 ? 444 TRP A CZ2 1 ATOM 2153 C CZ3 . TRP A 1 138 ? 13.967 199.753 31.219 1.00 17.49 ? 444 TRP A CZ3 1 ATOM 2154 C CH2 . TRP A 1 138 ? 13.040 199.211 30.313 1.00 17.65 ? 444 TRP A CH2 1 ATOM 2155 H H . TRP A 1 138 ? 16.003 205.183 28.395 1.00 21.48 ? 444 TRP A H 1 ATOM 2156 H HA . TRP A 1 138 ? 16.731 204.886 30.890 1.00 26.78 ? 444 TRP A HA 1 ATOM 2157 H HB2 . TRP A 1 138 ? 14.708 204.173 31.344 1.00 23.33 ? 444 TRP A HB2 1 ATOM 2158 H HB3 . TRP A 1 138 ? 14.481 205.148 30.129 1.00 23.33 ? 444 TRP A HB3 1 ATOM 2159 H HD1 . TRP A 1 138 ? 13.087 204.231 28.183 1.00 18.00 ? 444 TRP A HD1 1 ATOM 2160 H HE1 . TRP A 1 138 ? 11.969 202.160 27.684 1.00 20.97 ? 444 TRP A HE1 1 ATOM 2161 H HE3 . TRP A 1 138 ? 14.966 201.431 31.738 1.00 17.54 ? 444 TRP A HE3 1 ATOM 2162 H HZ2 . TRP A 1 138 ? 11.894 199.597 28.706 1.00 18.57 ? 444 TRP A HZ2 1 ATOM 2163 H HZ3 . TRP A 1 138 ? 14.316 199.216 31.893 1.00 20.99 ? 444 TRP A HZ3 1 ATOM 2164 H HH2 . TRP A 1 138 ? 12.798 198.316 30.391 1.00 21.18 ? 444 TRP A HH2 1 ATOM 2165 N N . ASN A 1 139 ? 17.042 202.210 29.139 1.00 20.83 ? 445 ASN A N 1 ATOM 2166 C CA . ASN A 1 139 ? 17.814 200.961 29.127 1.00 15.90 ? 445 ASN A CA 1 ATOM 2167 C C . ASN A 1 139 ? 19.251 201.220 29.535 1.00 16.98 ? 445 ASN A C 1 ATOM 2168 O O . ASN A 1 139 ? 19.836 200.482 30.337 1.00 16.58 ? 445 ASN A O 1 ATOM 2169 C CB . ASN A 1 139 ? 17.841 200.306 27.740 1.00 13.23 ? 445 ASN A CB 1 ATOM 2170 C CG . ASN A 1 139 ? 16.620 199.483 27.416 1.00 17.38 ? 445 ASN A CG 1 ATOM 2171 O OD1 . ASN A 1 139 ? 16.567 198.877 26.338 1.00 20.17 ? 445 ASN A OD1 1 ATOM 2172 N ND2 . ASN A 1 139 ? 15.632 199.467 28.292 1.00 14.79 ? 445 ASN A ND2 1 ATOM 2173 H H . ASN A 1 139 ? 16.615 202.377 28.412 1.00 24.99 ? 445 ASN A H 1 ATOM 2174 H HA . ASN A 1 139 ? 17.424 200.334 29.755 1.00 19.08 ? 445 ASN A HA 1 ATOM 2175 H HB2 . ASN A 1 139 ? 17.913 201.002 27.068 1.00 15.88 ? 445 ASN A HB2 1 ATOM 2176 H HB3 . ASN A 1 139 ? 18.613 199.720 27.688 1.00 15.88 ? 445 ASN A HB3 1 ATOM 2177 H HD21 . ASN A 1 139 ? 14.923 199.006 28.133 1.00 17.75 ? 445 ASN A HD21 1 ATOM 2178 H HD22 . ASN A 1 139 ? 15.697 199.918 29.022 1.00 17.75 ? 445 ASN A HD22 1 ATOM 2179 N N . ARG A 1 140 ? 19.854 202.239 28.936 1.00 17.88 ? 446 ARG A N 1 ATOM 2180 C CA . ARG A 1 140 ? 21.253 202.521 29.201 1.00 26.49 ? 446 ARG A CA 1 ATOM 2181 C C . ARG A 1 140 ? 21.451 202.966 30.646 1.00 24.23 ? 446 ARG A C 1 ATOM 2182 O O . ARG A 1 140 ? 22.448 202.597 31.279 1.00 22.24 ? 446 ARG A O 1 ATOM 2183 C CB . ARG A 1 140 ? 21.748 203.575 28.211 1.00 22.80 ? 446 ARG A CB 1 ATOM 2184 C CG . ARG A 1 140 ? 23.250 203.602 28.046 1.00 32.69 ? 446 ARG A CG 1 ATOM 2185 C CD . ARG A 1 140 ? 23.674 204.442 26.866 1.00 39.14 ? 446 ARG A CD 1 ATOM 2186 N NE . ARG A 1 140 ? 23.208 203.889 25.591 1.00 29.73 ? 446 ARG A NE 1 ATOM 2187 C CZ . ARG A 1 140 ? 23.797 202.883 24.956 1.00 34.51 ? 446 ARG A CZ 1 ATOM 2188 N NH1 . ARG A 1 140 ? 24.867 202.296 25.488 1.00 30.77 ? 446 ARG A NH1 1 ATOM 2189 N NH2 . ARG A 1 140 ? 23.303 202.449 23.797 1.00 30.49 ? 446 ARG A NH2 1 ATOM 2190 H H . ARG A 1 140 ? 19.479 202.776 28.379 1.00 21.46 ? 446 ARG A H 1 ATOM 2191 H HA . ARG A 1 140 ? 21.770 201.712 29.063 1.00 31.79 ? 446 ARG A HA 1 ATOM 2192 H HB2 . ARG A 1 140 ? 21.357 203.395 27.342 1.00 27.36 ? 446 ARG A HB2 1 ATOM 2193 H HB3 . ARG A 1 140 ? 21.468 204.451 28.522 1.00 27.36 ? 446 ARG A HB3 1 ATOM 2194 H HG2 . ARG A 1 140 ? 23.651 203.978 28.845 1.00 39.22 ? 446 ARG A HG2 1 ATOM 2195 H HG3 . ARG A 1 140 ? 23.571 202.698 27.905 1.00 39.22 ? 446 ARG A HG3 1 ATOM 2196 H HD2 . ARG A 1 140 ? 23.303 205.334 26.961 1.00 46.97 ? 446 ARG A HD2 1 ATOM 2197 H HD3 . ARG A 1 140 ? 24.643 204.486 26.839 1.00 46.97 ? 446 ARG A HD3 1 ATOM 2198 H HE . ARG A 1 140 ? 22.491 204.217 25.248 1.00 35.68 ? 446 ARG A HE 1 ATOM 2199 H HH11 . ARG A 1 140 ? 25.185 202.576 26.236 1.00 36.92 ? 446 ARG A HH11 1 ATOM 2200 H HH12 . ARG A 1 140 ? 25.246 201.641 25.078 1.00 36.92 ? 446 ARG A HH12 1 ATOM 2201 H HH21 . ARG A 1 140 ? 22.609 202.826 23.457 1.00 36.59 ? 446 ARG A HH21 1 ATOM 2202 H HH22 . ARG A 1 140 ? 23.680 201.793 23.388 1.00 36.59 ? 446 ARG A HH22 1 ATOM 2203 N N . ARG A 1 141 ? 20.475 203.695 31.194 1.00 17.24 ? 447 ARG A N 1 ATOM 2204 C CA A ARG A 1 141 ? 20.576 204.180 32.564 0.50 22.86 ? 447 ARG A CA 1 ATOM 2205 C CA B ARG A 1 141 ? 20.580 204.177 32.571 0.50 22.93 ? 447 ARG A CA 1 ATOM 2206 C C . ARG A 1 141 ? 20.670 203.029 33.562 1.00 21.17 ? 447 ARG A C 1 ATOM 2207 O O . ARG A 1 141 ? 21.323 203.162 34.601 1.00 16.89 ? 447 ARG A O 1 ATOM 2208 C CB A ARG A 1 141 ? 19.372 205.086 32.837 0.50 23.99 ? 447 ARG A CB 1 ATOM 2209 C CB B ARG A 1 141 ? 19.383 205.066 32.931 0.50 23.92 ? 447 ARG A CB 1 ATOM 2210 C CG A ARG A 1 141 ? 19.276 205.690 34.216 0.50 29.43 ? 447 ARG A CG 1 ATOM 2211 C CG B ARG A 1 141 ? 19.396 205.573 34.387 0.50 29.41 ? 447 ARG A CG 1 ATOM 2212 C CD A ARG A 1 141 ? 18.455 207.001 34.206 0.50 26.07 ? 447 ARG A CD 1 ATOM 2213 C CD B ARG A 1 141 ? 18.069 206.215 34.829 0.50 27.65 ? 447 ARG A CD 1 ATOM 2214 N NE A ARG A 1 141 ? 17.437 207.060 33.150 0.50 23.67 ? 447 ARG A NE 1 ATOM 2215 N NE B ARG A 1 141 ? 18.255 207.078 35.991 0.50 28.66 ? 447 ARG A NE 1 ATOM 2216 C CZ A ARG A 1 141 ? 17.574 207.711 31.990 0.50 28.86 ? 447 ARG A CZ 1 ATOM 2217 C CZ B ARG A 1 141 ? 17.299 207.822 36.540 0.50 29.87 ? 447 ARG A CZ 1 ATOM 2218 N NH1 A ARG A 1 141 ? 18.692 208.378 31.715 0.50 30.51 ? 447 ARG A NH1 1 ATOM 2219 N NH1 B ARG A 1 141 ? 16.065 207.810 36.049 0.50 26.90 ? 447 ARG A NH1 1 ATOM 2220 N NH2 A ARG A 1 141 ? 16.583 207.709 31.103 0.50 18.83 ? 447 ARG A NH2 1 ATOM 2221 N NH2 B ARG A 1 141 ? 17.580 208.589 37.579 0.50 30.14 ? 447 ARG A NH2 1 ATOM 2222 H H A ARG A 1 141 ? 19.749 203.920 30.791 0.50 20.69 ? 447 ARG A H 1 ATOM 2223 H H B ARG A 1 141 ? 19.750 203.923 30.792 0.50 20.69 ? 447 ARG A H 1 ATOM 2224 H HA A ARG A 1 141 ? 21.380 204.717 32.650 0.50 27.43 ? 447 ARG A HA 1 ATOM 2225 H HA B ARG A 1 141 ? 21.385 204.710 32.657 0.50 27.52 ? 447 ARG A HA 1 ATOM 2226 H HB2 A ARG A 1 141 ? 19.395 205.820 32.203 0.50 28.79 ? 447 ARG A HB2 1 ATOM 2227 H HB2 B ARG A 1 141 ? 19.384 205.842 32.348 0.50 28.70 ? 447 ARG A HB2 1 ATOM 2228 H HB3 A ARG A 1 141 ? 18.565 204.566 32.696 0.50 28.79 ? 447 ARG A HB3 1 ATOM 2229 H HB3 B ARG A 1 141 ? 18.567 204.559 32.801 0.50 28.70 ? 447 ARG A HB3 1 ATOM 2230 H HG2 A ARG A 1 141 ? 18.839 205.062 34.811 0.50 35.31 ? 447 ARG A HG2 1 ATOM 2231 H HG2 B ARG A 1 141 ? 19.574 204.824 34.978 0.50 35.29 ? 447 ARG A HG2 1 ATOM 2232 H HG3 A ARG A 1 141 ? 20.168 205.893 34.538 0.50 35.31 ? 447 ARG A HG3 1 ATOM 2233 H HG3 B ARG A 1 141 ? 20.094 206.239 34.481 0.50 35.29 ? 447 ARG A HG3 1 ATOM 2234 H HD2 A ARG A 1 141 ? 18.002 207.091 35.059 0.50 31.29 ? 447 ARG A HD2 1 ATOM 2235 H HD2 B ARG A 1 141 ? 17.717 206.754 34.103 0.50 33.18 ? 447 ARG A HD2 1 ATOM 2236 H HD3 A ARG A 1 141 ? 19.060 207.747 34.075 0.50 31.29 ? 447 ARG A HD3 1 ATOM 2237 H HD3 B ARG A 1 141 ? 17.439 205.517 35.066 0.50 33.18 ? 447 ARG A HD3 1 ATOM 2238 H HE A ARG A 1 141 ? 16.696 206.645 33.288 0.50 28.41 ? 447 ARG A HE 1 ATOM 2239 H HE B ARG A 1 141 ? 19.038 207.108 36.346 0.50 34.40 ? 447 ARG A HE 1 ATOM 2240 H HH11 A ARG A 1 141 ? 19.337 208.389 32.282 0.50 36.61 ? 447 ARG A HH11 1 ATOM 2241 H HH11 B ARG A 1 141 ? 15.878 207.319 35.369 0.50 32.28 ? 447 ARG A HH11 1 ATOM 2242 H HH12 A ARG A 1 141 ? 18.770 208.795 30.966 0.50 36.61 ? 447 ARG A HH12 1 ATOM 2243 H HH12 B ARG A 1 141 ? 15.453 208.293 36.412 0.50 32.28 ? 447 ARG A HH12 1 ATOM 2244 H HH21 A ARG A 1 141 ? 15.856 207.281 31.272 0.50 22.59 ? 447 ARG A HH21 1 ATOM 2245 H HH21 B ARG A 1 141 ? 18.377 208.598 37.903 0.50 36.17 ? 447 ARG A HH21 1 ATOM 2246 H HH22 A ARG A 1 141 ? 16.672 208.127 30.357 0.50 22.59 ? 447 ARG A HH22 1 ATOM 2247 H HH22 B ARG A 1 141 ? 16.963 209.065 37.942 0.50 36.17 ? 447 ARG A HH22 1 ATOM 2248 N N . TYR A 1 142 ? 20.044 201.887 33.255 1.00 21.84 ? 448 TYR A N 1 ATOM 2249 C CA . TYR A 1 142 ? 19.986 200.768 34.179 1.00 22.52 ? 448 TYR A CA 1 ATOM 2250 C C . TYR A 1 142 ? 20.806 199.574 33.710 1.00 20.70 ? 448 TYR A C 1 ATOM 2251 O O . TYR A 1 142 ? 20.513 198.431 34.068 1.00 22.79 ? 448 TYR A O 1 ATOM 2252 C CB . TYR A 1 142 ? 18.531 200.396 34.430 1.00 18.22 ? 448 TYR A CB 1 ATOM 2253 C CG . TYR A 1 142 ? 17.839 201.447 35.245 1.00 20.31 ? 448 TYR A CG 1 ATOM 2254 C CD1 . TYR A 1 142 ? 18.268 201.735 36.549 1.00 20.68 ? 448 TYR A CD1 1 ATOM 2255 C CD2 . TYR A 1 142 ? 16.771 202.168 34.731 1.00 16.79 ? 448 TYR A CD2 1 ATOM 2256 C CE1 . TYR A 1 142 ? 17.640 202.696 37.316 1.00 21.76 ? 448 TYR A CE1 1 ATOM 2257 C CE2 . TYR A 1 142 ? 16.132 203.142 35.496 1.00 19.39 ? 448 TYR A CE2 1 ATOM 2258 C CZ . TYR A 1 142 ? 16.577 203.403 36.790 1.00 22.65 ? 448 TYR A CZ 1 ATOM 2259 O OH . TYR A 1 142 ? 15.968 204.373 37.561 1.00 21.25 ? 448 TYR A OH 1 ATOM 2260 H H . TYR A 1 142 ? 19.643 201.742 32.508 1.00 26.21 ? 448 TYR A H 1 ATOM 2261 H HA . TYR A 1 142 ? 20.359 201.056 35.027 1.00 27.02 ? 448 TYR A HA 1 ATOM 2262 H HB2 . TYR A 1 142 ? 18.069 200.314 33.581 1.00 21.87 ? 448 TYR A HB2 1 ATOM 2263 H HB3 . TYR A 1 142 ? 18.493 199.558 34.917 1.00 21.87 ? 448 TYR A HB3 1 ATOM 2264 H HD1 . TYR A 1 142 ? 18.982 201.260 36.909 1.00 24.81 ? 448 TYR A HD1 1 ATOM 2265 H HD2 . TYR A 1 142 ? 16.472 201.993 33.868 1.00 20.15 ? 448 TYR A HD2 1 ATOM 2266 H HE1 . TYR A 1 142 ? 17.939 202.874 38.179 1.00 26.11 ? 448 TYR A HE1 1 ATOM 2267 H HE2 . TYR A 1 142 ? 15.417 203.620 35.142 1.00 23.27 ? 448 TYR A HE2 1 ATOM 2268 H HH . TYR A 1 142 ? 15.339 204.728 37.131 1.00 25.50 ? 448 TYR A HH 1 ATOM 2269 N N . GLY A 1 143 ? 21.873 199.822 32.962 1.00 21.83 ? 449 GLY A N 1 ATOM 2270 C CA . GLY A 1 143 ? 22.888 198.801 32.736 1.00 27.84 ? 449 GLY A CA 1 ATOM 2271 C C . GLY A 1 143 ? 23.131 198.336 31.302 1.00 26.80 ? 449 GLY A C 1 ATOM 2272 O O . GLY A 1 143 ? 24.086 197.571 31.096 1.00 24.78 ? 449 GLY A O 1 ATOM 2273 H H . GLY A 1 143 ? 22.034 200.573 32.575 1.00 26.20 ? 449 GLY A H 1 ATOM 2274 H HA2 . GLY A 1 143 ? 23.733 199.132 33.078 1.00 33.41 ? 449 GLY A HA2 1 ATOM 2275 H HA3 . GLY A 1 143 ? 22.650 198.018 33.256 1.00 33.41 ? 449 GLY A HA3 1 ATOM 2276 N N . PHE A 1 144 ? 22.353 198.710 30.283 1.00 25.70 ? 450 PHE A N 1 ATOM 2277 C CA . PHE A 1 144 ? 22.658 198.229 28.933 1.00 24.19 ? 450 PHE A CA 1 ATOM 2278 C C . PHE A 1 144 ? 23.838 199.010 28.386 1.00 22.39 ? 450 PHE A C 1 ATOM 2279 O O . PHE A 1 144 ? 23.757 200.231 28.263 1.00 27.74 ? 450 PHE A O 1 ATOM 2280 C CB . PHE A 1 144 ? 21.478 198.375 27.974 1.00 22.94 ? 450 PHE A CB 1 ATOM 2281 C CG . PHE A 1 144 ? 21.661 197.587 26.688 1.00 22.23 ? 450 PHE A CG 1 ATOM 2282 C CD1 . PHE A 1 144 ? 22.433 198.089 25.648 1.00 17.31 ? 450 PHE A CD1 1 ATOM 2283 C CD2 . PHE A 1 144 ? 21.107 196.327 26.554 1.00 15.89 ? 450 PHE A CD2 1 ATOM 2284 C CE1 . PHE A 1 144 ? 22.626 197.353 24.498 1.00 25.91 ? 450 PHE A CE1 1 ATOM 2285 C CE2 . PHE A 1 144 ? 21.280 195.585 25.396 1.00 20.09 ? 450 PHE A CE2 1 ATOM 2286 C CZ . PHE A 1 144 ? 22.038 196.080 24.371 1.00 18.09 ? 450 PHE A CZ 1 ATOM 2287 H H . PHE A 1 144 ? 21.666 199.224 30.341 1.00 30.84 ? 450 PHE A H 1 ATOM 2288 H HA . PHE A 1 144 ? 22.904 197.292 28.974 1.00 29.03 ? 450 PHE A HA 1 ATOM 2289 H HB2 . PHE A 1 144 ? 20.674 198.052 28.411 1.00 27.53 ? 450 PHE A HB2 1 ATOM 2290 H HB3 . PHE A 1 144 ? 21.375 199.310 27.740 1.00 27.53 ? 450 PHE A HB3 1 ATOM 2291 H HD1 . PHE A 1 144 ? 22.826 198.928 25.730 1.00 20.77 ? 450 PHE A HD1 1 ATOM 2292 H HD2 . PHE A 1 144 ? 20.592 195.979 27.246 1.00 19.07 ? 450 PHE A HD2 1 ATOM 2293 H HE1 . PHE A 1 144 ? 23.135 197.702 23.802 1.00 31.09 ? 450 PHE A HE1 1 ATOM 2294 H HE2 . PHE A 1 144 ? 20.892 194.743 25.322 1.00 24.11 ? 450 PHE A HE2 1 ATOM 2295 H HZ . PHE A 1 144 ? 22.157 195.584 23.593 1.00 21.70 ? 450 PHE A HZ 1 ATOM 2296 N N . ASN A 1 145 ? 24.932 198.326 28.052 1.00 24.84 ? 451 ASN A N 1 ATOM 2297 C CA A ASN A 1 145 ? 26.098 198.984 27.470 0.45 35.72 ? 451 ASN A CA 1 ATOM 2298 C CA B ASN A 1 145 ? 26.104 198.976 27.472 0.55 35.73 ? 451 ASN A CA 1 ATOM 2299 C C . ASN A 1 145 ? 26.198 198.688 25.978 1.00 37.93 ? 451 ASN A C 1 ATOM 2300 O O . ASN A 1 145 ? 25.927 199.573 25.163 1.00 43.86 ? 451 ASN A O 1 ATOM 2301 C CB A ASN A 1 145 ? 27.387 198.591 28.202 0.45 41.12 ? 451 ASN A CB 1 ATOM 2302 C CB B ASN A 1 145 ? 27.383 198.537 28.190 0.55 41.15 ? 451 ASN A CB 1 ATOM 2303 C CG A ASN A 1 145 ? 27.548 197.091 28.365 0.45 41.39 ? 451 ASN A CG 1 ATOM 2304 C CG B ASN A 1 145 ? 27.448 199.029 29.628 0.55 38.42 ? 451 ASN A CG 1 ATOM 2305 O OD1 A ASN A 1 145 ? 26.578 196.369 28.616 0.45 41.54 ? 451 ASN A OD1 1 ATOM 2306 O OD1 B ASN A 1 145 ? 27.031 200.146 29.938 0.55 38.89 ? 451 ASN A OD1 1 ATOM 2307 N ND2 A ASN A 1 145 ? 28.784 196.613 28.228 0.45 42.29 ? 451 ASN A ND2 1 ATOM 2308 N ND2 B ASN A 1 145 ? 27.982 198.198 30.510 0.55 36.97 ? 451 ASN A ND2 1 ATOM 2309 H H A ASN A 1 145 ? 25.023 197.477 28.153 0.45 29.81 ? 451 ASN A H 1 ATOM 2310 H H B ASN A 1 145 ? 25.020 197.477 28.153 0.55 29.81 ? 451 ASN A H 1 ATOM 2311 H HA A ASN A 1 145 ? 25.990 199.942 27.569 0.45 42.86 ? 451 ASN A HA 1 ATOM 2312 H HA B ASN A 1 145 ? 26.016 199.935 27.584 0.55 42.87 ? 451 ASN A HA 1 ATOM 2313 H HB2 A ASN A 1 145 ? 28.148 198.919 27.697 0.45 49.35 ? 451 ASN A HB2 1 ATOM 2314 H HB2 B ASN A 1 145 ? 27.421 197.568 28.203 0.55 49.38 ? 451 ASN A HB2 1 ATOM 2315 H HB3 A ASN A 1 145 ? 27.381 198.989 29.086 0.45 49.35 ? 451 ASN A HB3 1 ATOM 2316 H HB3 B ASN A 1 145 ? 28.150 198.894 27.716 0.55 49.38 ? 451 ASN A HB3 1 ATOM 2317 H HD21 A ASN A 1 145 ? 28.930 195.770 28.311 0.45 50.75 ? 451 ASN A HD21 1 ATOM 2318 H HD21 B ASN A 1 145 ? 28.042 198.429 31.336 0.55 44.37 ? 451 ASN A HD21 1 ATOM 2319 H HD22 A ASN A 1 145 ? 29.435 197.148 28.056 0.45 50.75 ? 451 ASN A HD22 1 ATOM 2320 H HD22 B ASN A 1 145 ? 28.268 197.428 30.256 0.55 44.37 ? 451 ASN A HD22 1 ATOM 2321 N N . ASN A 1 146 ? 26.567 197.464 25.590 1.00 35.52 ? 452 ASN A N 1 ATOM 2322 C CA . ASN A 1 146 ? 26.784 197.121 24.190 1.00 34.16 ? 452 ASN A CA 1 ATOM 2323 C C . ASN A 1 146 ? 26.175 195.763 23.882 1.00 33.23 ? 452 ASN A C 1 ATOM 2324 O O . ASN A 1 146 ? 25.752 195.023 24.771 1.00 34.34 ? 452 ASN A O 1 ATOM 2325 C CB . ASN A 1 146 ? 28.278 197.073 23.832 1.00 33.49 ? 452 ASN A CB 1 ATOM 2326 C CG . ASN A 1 146 ? 28.901 198.445 23.693 1.00 51.58 ? 452 ASN A CG 1 ATOM 2327 O OD1 . ASN A 1 146 ? 28.371 199.323 23.009 1.00 63.21 ? 452 ASN A OD1 1 ATOM 2328 N ND2 . ASN A 1 146 ? 30.049 198.635 24.339 1.00 70.34 ? 452 ASN A ND2 1 ATOM 2329 H H . ASN A 1 146 ? 26.698 196.808 26.131 1.00 42.62 ? 452 ASN A H 1 ATOM 2330 H HA . ASN A 1 146 ? 26.356 197.784 23.626 1.00 40.99 ? 452 ASN A HA 1 ATOM 2331 H HB2 . ASN A 1 146 ? 28.754 196.598 24.531 1.00 40.19 ? 452 ASN A HB2 1 ATOM 2332 H HB3 . ASN A 1 146 ? 28.384 196.610 22.986 1.00 40.19 ? 452 ASN A HB3 1 ATOM 2333 H HD21 . ASN A 1 146 ? 30.447 199.396 24.294 1.00 84.41 ? 452 ASN A HD21 1 ATOM 2334 H HD22 . ASN A 1 146 ? 30.393 197.997 24.801 1.00 84.41 ? 452 ASN A HD22 1 ATOM 2335 N N . PHE A 1 147 ? 26.144 195.446 22.598 1.00 30.41 ? 453 PHE A N 1 ATOM 2336 C CA . PHE A 1 147 ? 25.907 194.091 22.138 1.00 31.22 ? 453 PHE A CA 1 ATOM 2337 C C . PHE A 1 147 ? 27.254 193.408 21.961 1.00 32.52 ? 453 PHE A C 1 ATOM 2338 O O . PHE A 1 147 ? 28.275 194.065 21.744 1.00 41.74 ? 453 PHE A O 1 ATOM 2339 C CB . PHE A 1 147 ? 25.123 194.076 20.818 1.00 28.88 ? 453 PHE A CB 1 ATOM 2340 C CG . PHE A 1 147 ? 23.768 194.730 20.905 1.00 24.20 ? 453 PHE A CG 1 ATOM 2341 C CD1 . PHE A 1 147 ? 23.623 196.084 20.639 1.00 17.59 ? 453 PHE A CD1 1 ATOM 2342 C CD2 . PHE A 1 147 ? 22.642 193.994 21.251 1.00 17.73 ? 453 PHE A CD2 1 ATOM 2343 C CE1 . PHE A 1 147 ? 22.392 196.688 20.712 1.00 15.54 ? 453 PHE A CE1 1 ATOM 2344 C CE2 . PHE A 1 147 ? 21.400 194.593 21.319 1.00 14.10 ? 453 PHE A CE2 1 ATOM 2345 C CZ . PHE A 1 147 ? 21.278 195.952 21.050 1.00 20.23 ? 453 PHE A CZ 1 ATOM 2346 H H . PHE A 1 147 ? 26.261 196.012 21.960 1.00 36.50 ? 453 PHE A H 1 ATOM 2347 H HA . PHE A 1 147 ? 25.398 193.605 22.806 1.00 37.47 ? 453 PHE A HA 1 ATOM 2348 H HB2 . PHE A 1 147 ? 25.637 194.548 20.144 1.00 34.66 ? 453 PHE A HB2 1 ATOM 2349 H HB3 . PHE A 1 147 ? 24.989 193.155 20.545 1.00 34.66 ? 453 PHE A HB3 1 ATOM 2350 H HD1 . PHE A 1 147 ? 24.369 196.588 20.407 1.00 21.11 ? 453 PHE A HD1 1 ATOM 2351 H HD2 . PHE A 1 147 ? 22.725 193.084 21.429 1.00 21.28 ? 453 PHE A HD2 1 ATOM 2352 H HE1 . PHE A 1 147 ? 22.310 197.596 20.530 1.00 18.65 ? 453 PHE A HE1 1 ATOM 2353 H HE2 . PHE A 1 147 ? 20.652 194.093 21.553 1.00 16.92 ? 453 PHE A HE2 1 ATOM 2354 H HZ . PHE A 1 147 ? 20.446 196.364 21.100 1.00 24.27 ? 453 PHE A HZ 1 ATOM 2355 N N . ASN A 1 148 ? 27.256 192.085 22.089 1.00 27.51 ? 454 ASN A N 1 ATOM 2356 C CA . ASN A 1 148 ? 28.443 191.253 21.874 1.00 45.58 ? 454 ASN A CA 1 ATOM 2357 C C . ASN A 1 148 ? 28.084 190.234 20.796 1.00 40.41 ? 454 ASN A C 1 ATOM 2358 O O . ASN A 1 148 ? 27.702 189.106 21.112 1.00 42.33 ? 454 ASN A O 1 ATOM 2359 C CB . ASN A 1 148 ? 28.884 190.555 23.203 1.00 45.08 ? 454 ASN A CB 1 ATOM 2360 C CG . ASN A 1 148 ? 29.965 189.506 22.988 1.00 60.95 ? 454 ASN A CG 1 ATOM 2361 O OD1 . ASN A 1 148 ? 30.866 189.690 22.171 1.00 70.59 ? 454 ASN A OD1 1 ATOM 2362 N ND2 . ASN A 1 148 ? 29.872 188.392 23.722 1.00 62.93 ? 454 ASN A ND2 1 ATOM 2363 H H . ASN A 1 148 ? 26.560 191.629 22.307 1.00 33.02 ? 454 ASN A H 1 ATOM 2364 H HA . ASN A 1 148 ? 29.175 191.802 21.552 1.00 54.70 ? 454 ASN A HA 1 ATOM 2365 H HB2 . ASN A 1 148 ? 29.233 191.226 23.811 1.00 54.10 ? 454 ASN A HB2 1 ATOM 2366 H HB3 . ASN A 1 148 ? 28.115 190.117 23.600 1.00 54.10 ? 454 ASN A HB3 1 ATOM 2367 H HD21 . ASN A 1 148 ? 29.219 188.314 24.276 1.00 75.51 ? 454 ASN A HD21 1 ATOM 2368 N N . LEU A 1 149 ? 28.190 190.633 19.525 1.00 43.44 ? 455 LEU A N 1 ATOM 2369 C CA . LEU A 1 149 ? 27.660 189.824 18.429 1.00 43.45 ? 455 LEU A CA 1 ATOM 2370 C C . LEU A 1 149 ? 28.663 189.622 17.301 1.00 38.73 ? 455 LEU A C 1 ATOM 2371 O O . LEU A 1 149 ? 29.529 190.462 17.046 1.00 43.72 ? 455 LEU A O 1 ATOM 2372 C CB . LEU A 1 149 ? 26.406 190.454 17.828 1.00 40.06 ? 455 LEU A CB 1 ATOM 2373 C CG . LEU A 1 149 ? 25.192 190.540 18.735 1.00 32.12 ? 455 LEU A CG 1 ATOM 2374 C CD1 . LEU A 1 149 ? 24.080 191.321 18.063 1.00 25.49 ? 455 LEU A CD1 1 ATOM 2375 C CD2 . LEU A 1 149 ? 24.725 189.144 19.091 1.00 39.25 ? 455 LEU A CD2 1 ATOM 2376 H H . LEU A 1 149 ? 28.565 191.365 19.274 1.00 52.12 ? 455 LEU A H 1 ATOM 2377 H HA . LEU A 1 149 ? 27.419 188.950 18.773 1.00 52.14 ? 455 LEU A HA 1 ATOM 2378 H HB2 . LEU A 1 149 ? 26.623 191.358 17.552 1.00 48.07 ? 455 LEU A HB2 1 ATOM 2379 H HB3 . LEU A 1 149 ? 26.148 189.935 17.050 1.00 48.07 ? 455 LEU A HB3 1 ATOM 2380 H HG . LEU A 1 149 ? 25.434 190.999 19.555 1.00 38.55 ? 455 LEU A HG 1 ATOM 2381 H HD11 . LEU A 1 149 ? 23.318 191.362 18.660 1.00 30.59 ? 455 LEU A HD11 1 ATOM 2382 H HD12 . LEU A 1 149 ? 24.398 192.217 17.868 1.00 30.59 ? 455 LEU A HD12 1 ATOM 2383 H HD13 . LEU A 1 149 ? 23.833 190.871 17.240 1.00 30.59 ? 455 LEU A HD13 1 ATOM 2384 H HD21 . LEU A 1 149 ? 23.950 189.208 19.670 1.00 47.10 ? 455 LEU A HD21 1 ATOM 2385 H HD22 . LEU A 1 149 ? 24.492 188.672 18.276 1.00 47.10 ? 455 LEU A HD22 1 ATOM 2386 H HD23 . LEU A 1 149 ? 25.443 188.679 19.549 1.00 47.10 ? 455 LEU A HD23 1 ATOM 2387 N N . SER A 1 150 ? 28.486 188.502 16.597 1.00 44.86 ? 456 SER A N 1 ATOM 2388 C CA . SER A 1 150 ? 29.267 188.143 15.419 1.00 44.98 ? 456 SER A CA 1 ATOM 2389 C C . SER A 1 150 ? 29.343 189.293 14.426 1.00 43.32 ? 456 SER A C 1 ATOM 2390 O O . SER A 1 150 ? 28.463 190.158 14.402 1.00 49.24 ? 456 SER A O 1 ATOM 2391 C CB . SER A 1 150 ? 28.646 186.927 14.729 1.00 48.37 ? 456 SER A CB 1 ATOM 2392 O OG . SER A 1 150 ? 28.952 185.723 15.408 1.00 54.53 ? 456 SER A OG 1 ATOM 2393 H H . SER A 1 150 ? 27.892 187.912 16.796 1.00 53.84 ? 456 SER A H 1 ATOM 2394 H HA . SER A 1 150 ? 30.170 187.913 15.690 1.00 53.97 ? 456 SER A HA 1 ATOM 2395 H HB2 . SER A 1 150 ? 27.682 187.038 14.708 1.00 58.04 ? 456 SER A HB2 1 ATOM 2396 H HB3 . SER A 1 150 ? 28.990 186.871 13.824 1.00 58.04 ? 456 SER A HB3 1 ATOM 2397 H HG . SER A 1 150 ? 28.600 185.072 15.011 1.00 65.44 ? 456 SER A HG 1 ATOM 2398 N N . SER A 1 151 ? 30.376 189.310 13.593 1.00 44.42 ? 457 SER A N 1 ATOM 2399 C CA . SER A 1 151 ? 30.441 190.305 12.533 1.00 53.50 ? 457 SER A CA 1 ATOM 2400 C C . SER A 1 151 ? 29.311 190.070 11.535 1.00 45.77 ? 457 SER A C 1 ATOM 2401 O O . SER A 1 151 ? 29.016 188.930 11.159 1.00 43.64 ? 457 SER A O 1 ATOM 2402 C CB . SER A 1 151 ? 31.799 190.257 11.825 1.00 63.63 ? 457 SER A CB 1 ATOM 2403 O OG . SER A 1 151 ? 32.042 191.472 11.120 1.00 70.18 ? 457 SER A OG 1 ATOM 2404 H H . SER A 1 151 ? 31.042 188.766 13.618 1.00 53.31 ? 457 SER A H 1 ATOM 2405 H HA . SER A 1 151 ? 30.329 191.189 12.917 1.00 64.20 ? 457 SER A HA 1 ATOM 2406 H HB2 . SER A 1 151 ? 32.496 190.130 12.487 1.00 76.35 ? 457 SER A HB2 1 ATOM 2407 H HB3 . SER A 1 151 ? 31.801 189.519 11.195 1.00 76.35 ? 457 SER A HB3 1 ATOM 2408 H HG . SER A 1 151 ? 32.788 191.436 10.736 1.00 84.21 ? 457 SER A HG 1 ATOM 2409 N N . HIS A 1 152 ? 28.669 191.166 11.125 1.00 34.97 ? 458 HIS A N 1 ATOM 2410 C CA . HIS A 1 152 ? 27.530 191.214 10.199 1.00 32.56 ? 458 HIS A CA 1 ATOM 2411 C C . HIS A 1 152 ? 26.218 190.787 10.846 1.00 28.93 ? 458 HIS A C 1 ATOM 2412 O O . HIS A 1 152 ? 25.206 190.707 10.145 1.00 27.52 ? 458 HIS A O 1 ATOM 2413 C CB . HIS A 1 152 ? 27.785 190.380 8.939 1.00 28.50 ? 458 HIS A CB 1 ATOM 2414 C CG . HIS A 1 152 ? 29.012 190.798 8.203 1.00 28.15 ? 458 HIS A CG 1 ATOM 2415 N ND1 . HIS A 1 152 ? 29.919 189.900 7.689 1.00 32.90 ? 458 HIS A ND1 1 ATOM 2416 C CD2 . HIS A 1 152 ? 29.502 192.030 7.927 1.00 30.59 ? 458 HIS A CD2 1 ATOM 2417 C CE1 . HIS A 1 152 ? 30.904 190.562 7.106 1.00 33.13 ? 458 HIS A CE1 1 ATOM 2418 N NE2 . HIS A 1 152 ? 30.678 191.855 7.243 1.00 29.72 ? 458 HIS A NE2 1 ATOM 2419 H H . HIS A 1 152 ? 28.894 191.952 11.391 1.00 41.97 ? 458 HIS A H 1 ATOM 2420 H HA . HIS A 1 152 ? 27.418 192.133 9.912 1.00 39.07 ? 458 HIS A HA 1 ATOM 2421 H HB2 . HIS A 1 152 ? 27.891 189.450 9.193 1.00 34.20 ? 458 HIS A HB2 1 ATOM 2422 H HB3 . HIS A 1 152 ? 27.029 190.476 8.339 1.00 34.20 ? 458 HIS A HB3 1 ATOM 2423 H HD2 . HIS A 1 152 ? 29.111 192.843 8.154 1.00 36.70 ? 458 HIS A HD2 1 ATOM 2424 H HE1 . HIS A 1 152 ? 31.638 190.181 6.681 1.00 39.75 ? 458 HIS A HE1 1 ATOM 2425 H HE2 . HIS A 1 152 ? 31.181 192.485 6.945 1.00 35.66 ? 458 HIS A HE2 1 ATOM 2426 N N . SER A 1 153 ? 26.185 190.545 12.153 1.00 20.63 ? 459 SER A N 1 ATOM 2427 C CA . SER A 1 153 ? 24.916 190.371 12.841 1.00 18.64 ? 459 SER A CA 1 ATOM 2428 C C . SER A 1 153 ? 24.235 191.724 12.991 1.00 20.36 ? 459 SER A C 1 ATOM 2429 O O . SER A 1 153 ? 24.870 192.712 13.370 1.00 20.99 ? 459 SER A O 1 ATOM 2430 C CB . SER A 1 153 ? 25.136 189.730 14.216 1.00 25.76 ? 459 SER A CB 1 ATOM 2431 O OG . SER A 1 153 ? 25.792 188.484 14.108 1.00 32.34 ? 459 SER A OG 1 ATOM 2432 H H . SER A 1 153 ? 26.878 190.478 12.658 1.00 24.76 ? 459 SER A H 1 ATOM 2433 H HA . SER A 1 153 ? 24.340 189.791 12.319 1.00 22.37 ? 459 SER A HA 1 ATOM 2434 H HB2 . SER A 1 153 ? 25.678 190.325 14.756 1.00 30.91 ? 459 SER A HB2 1 ATOM 2435 H HB3 . SER A 1 153 ? 24.274 189.594 14.639 1.00 30.91 ? 459 SER A HB3 1 ATOM 2436 H HG . SER A 1 153 ? 25.333 187.956 13.643 1.00 38.81 ? 459 SER A HG 1 ATOM 2437 N N . VAL A 1 154 ? 22.941 191.773 12.690 1.00 18.41 ? 460 VAL A N 1 ATOM 2438 C CA . VAL A 1 154 ? 22.177 193.015 12.687 1.00 15.03 ? 460 VAL A CA 1 ATOM 2439 C C . VAL A 1 154 ? 21.042 192.870 13.698 1.00 19.61 ? 460 VAL A C 1 ATOM 2440 O O . VAL A 1 154 ? 20.187 191.983 13.561 1.00 18.49 ? 460 VAL A O 1 ATOM 2441 C CB . VAL A 1 154 ? 21.635 193.351 11.293 1.00 17.61 ? 460 VAL A CB 1 ATOM 2442 C CG1 . VAL A 1 154 ? 20.874 194.666 11.336 1.00 19.15 ? 460 VAL A CG1 1 ATOM 2443 C CG2 . VAL A 1 154 ? 22.781 193.413 10.239 1.00 17.68 ? 460 VAL A CG2 1 ATOM 2444 H H . VAL A 1 154 ? 22.474 191.083 12.479 1.00 22.09 ? 460 VAL A H 1 ATOM 2445 H HA . VAL A 1 154 ? 22.749 193.744 12.974 1.00 18.04 ? 460 VAL A HA 1 ATOM 2446 H HB . VAL A 1 154 ? 21.015 192.656 11.021 1.00 21.13 ? 460 VAL A HB 1 ATOM 2447 H HG11 . VAL A 1 154 ? 20.537 194.864 10.448 1.00 22.98 ? 460 VAL A HG11 1 ATOM 2448 H HG12 . VAL A 1 154 ? 20.135 194.582 11.959 1.00 22.98 ? 460 VAL A HG12 1 ATOM 2449 H HG13 . VAL A 1 154 ? 21.475 195.369 11.627 1.00 22.98 ? 460 VAL A HG13 1 ATOM 2450 H HG21 . VAL A 1 154 ? 22.401 193.627 9.372 1.00 21.21 ? 460 VAL A HG21 1 ATOM 2451 H HG22 . VAL A 1 154 ? 23.415 194.099 10.501 1.00 21.21 ? 460 VAL A HG22 1 ATOM 2452 H HG23 . VAL A 1 154 ? 23.223 192.551 10.202 1.00 21.21 ? 460 VAL A HG23 1 ATOM 2453 N N . VAL A 1 155 ? 21.049 193.732 14.721 1.00 15.55 ? 461 VAL A N 1 ATOM 2454 C CA . VAL A 1 155 ? 20.043 193.693 15.773 1.00 14.54 ? 461 VAL A CA 1 ATOM 2455 C C . VAL A 1 155 ? 18.711 194.232 15.261 1.00 15.74 ? 461 VAL A C 1 ATOM 2456 O O . VAL A 1 155 ? 18.652 195.144 14.422 1.00 15.27 ? 461 VAL A O 1 ATOM 2457 C CB . VAL A 1 155 ? 20.538 194.504 16.990 1.00 16.24 ? 461 VAL A CB 1 ATOM 2458 C CG1 . VAL A 1 155 ? 19.451 194.679 18.023 1.00 16.94 ? 461 VAL A CG1 1 ATOM 2459 C CG2 . VAL A 1 155 ? 21.727 193.826 17.626 1.00 19.31 ? 461 VAL A CG2 1 ATOM 2460 H H . VAL A 1 155 ? 21.636 194.353 14.824 1.00 18.66 ? 461 VAL A H 1 ATOM 2461 H HA . VAL A 1 155 ? 19.910 192.775 16.055 1.00 17.45 ? 461 VAL A HA 1 ATOM 2462 H HB . VAL A 1 155 ? 20.816 195.385 16.693 1.00 19.49 ? 461 VAL A HB 1 ATOM 2463 H HG11 . VAL A 1 155 ? 19.804 195.191 18.767 1.00 20.33 ? 461 VAL A HG11 1 ATOM 2464 H HG12 . VAL A 1 155 ? 18.706 195.150 17.620 1.00 20.33 ? 461 VAL A HG12 1 ATOM 2465 H HG13 . VAL A 1 155 ? 19.164 193.804 18.330 1.00 20.33 ? 461 VAL A HG13 1 ATOM 2466 H HG21 . VAL A 1 155 ? 22.020 194.352 18.386 1.00 23.18 ? 461 VAL A HG21 1 ATOM 2467 H HG22 . VAL A 1 155 ? 21.465 192.939 17.918 1.00 23.18 ? 461 VAL A HG22 1 ATOM 2468 H HG23 . VAL A 1 155 ? 22.440 193.762 16.972 1.00 23.18 ? 461 VAL A HG23 1 ATOM 2469 N N . TYR A 1 156 ? 17.625 193.672 15.784 1.00 9.98 ? 462 TYR A N 1 ATOM 2470 C CA . TYR A 1 156 ? 16.314 194.293 15.671 1.00 15.12 ? 462 TYR A CA 1 ATOM 2471 C C . TYR A 1 156 ? 15.517 194.000 16.931 1.00 12.22 ? 462 TYR A C 1 ATOM 2472 O O . TYR A 1 156 ? 15.595 192.904 17.494 1.00 14.95 ? 462 TYR A O 1 ATOM 2473 C CB . TYR A 1 156 ? 15.531 193.808 14.449 1.00 15.46 ? 462 TYR A CB 1 ATOM 2474 C CG . TYR A 1 156 ? 15.338 192.304 14.410 1.00 14.64 ? 462 TYR A CG 1 ATOM 2475 C CD1 . TYR A 1 156 ? 16.300 191.479 13.864 1.00 16.90 ? 462 TYR A CD1 1 ATOM 2476 C CD2 . TYR A 1 156 ? 14.194 191.720 14.932 1.00 15.71 ? 462 TYR A CD2 1 ATOM 2477 C CE1 . TYR A 1 156 ? 16.127 190.102 13.830 1.00 20.58 ? 462 TYR A CE1 1 ATOM 2478 C CE2 . TYR A 1 156 ? 14.004 190.349 14.899 1.00 13.99 ? 462 TYR A CE2 1 ATOM 2479 C CZ . TYR A 1 156 ? 14.973 189.548 14.360 1.00 14.59 ? 462 TYR A CZ 1 ATOM 2480 O OH . TYR A 1 156 ? 14.783 188.201 14.357 1.00 19.24 ? 462 TYR A OH 1 ATOM 2481 H H . TYR A 1 156 ? 17.622 192.926 16.212 1.00 11.98 ? 462 TYR A H 1 ATOM 2482 H HA . TYR A 1 156 ? 16.423 195.254 15.598 1.00 18.14 ? 462 TYR A HA 1 ATOM 2483 H HB2 . TYR A 1 156 ? 14.654 194.221 14.455 1.00 18.55 ? 462 TYR A HB2 1 ATOM 2484 H HB3 . TYR A 1 156 ? 16.011 194.067 13.646 1.00 18.55 ? 462 TYR A HB3 1 ATOM 2485 H HD1 . TYR A 1 156 ? 17.076 191.851 13.511 1.00 20.28 ? 462 TYR A HD1 1 ATOM 2486 H HD2 . TYR A 1 156 ? 13.535 192.262 15.302 1.00 18.85 ? 462 TYR A HD2 1 ATOM 2487 H HE1 . TYR A 1 156 ? 16.784 189.556 13.464 1.00 24.70 ? 462 TYR A HE1 1 ATOM 2488 H HE2 . TYR A 1 156 ? 13.233 189.974 15.260 1.00 16.79 ? 462 TYR A HE2 1 ATOM 2489 H HH . TYR A 1 156 ? 15.442 187.818 14.004 1.00 23.09 ? 462 TYR A HH 1 ATOM 2490 N N . SER A 1 157 ? 14.742 194.986 17.353 1.00 13.36 ? 463 SER A N 1 ATOM 2491 C CA . SER A 1 157 ? 13.817 194.818 18.456 1.00 15.26 ? 463 SER A CA 1 ATOM 2492 C C . SER A 1 157 ? 12.533 194.170 17.974 1.00 12.51 ? 463 SER A C 1 ATOM 2493 O O . SER A 1 157 ? 12.032 194.480 16.896 1.00 17.62 ? 463 SER A O 1 ATOM 2494 C CB . SER A 1 157 ? 13.491 196.165 19.084 1.00 19.56 ? 463 SER A CB 1 ATOM 2495 O OG . SER A 1 157 ? 12.360 196.043 19.938 1.00 23.30 ? 463 SER A OG 1 ATOM 2496 H H . SER A 1 157 ? 14.735 195.774 17.009 1.00 16.04 ? 463 SER A H 1 ATOM 2497 H HA . SER A 1 157 ? 14.217 194.250 19.132 1.00 18.31 ? 463 SER A HA 1 ATOM 2498 H HB2 . SER A 1 157 ? 14.252 196.466 19.604 1.00 23.47 ? 463 SER A HB2 1 ATOM 2499 H HB3 . SER A 1 157 ? 13.291 196.803 18.381 1.00 23.47 ? 463 SER A HB3 1 ATOM 2500 H HG . SER A 1 157 ? 12.181 196.787 20.284 1.00 27.96 ? 463 SER A HG 1 ATOM 2501 N N . ARG A 1 158 ? 12.001 193.264 18.782 1.00 15.56 ? 464 ARG A N 1 ATOM 2502 C CA . ARG A 1 158 ? 10.671 192.733 18.548 1.00 14.51 ? 464 ARG A CA 1 ATOM 2503 C C . ARG A 1 158 ? 9.614 193.575 19.221 1.00 13.10 ? 464 ARG A C 1 ATOM 2504 O O . ARG A 1 158 ? 8.544 193.791 18.646 1.00 13.27 ? 464 ARG A O 1 ATOM 2505 C CB . ARG A 1 158 ? 10.564 191.302 19.079 1.00 14.75 ? 464 ARG A CB 1 ATOM 2506 C CG . ARG A 1 158 ? 11.456 190.318 18.410 1.00 22.38 ? 464 ARG A CG 1 ATOM 2507 C CD . ARG A 1 158 ? 11.424 188.983 19.177 1.00 20.71 ? 464 ARG A CD 1 ATOM 2508 N NE . ARG A 1 158 ? 12.178 187.978 18.442 1.00 16.30 ? 464 ARG A NE 1 ATOM 2509 C CZ . ARG A 1 158 ? 12.879 186.988 18.982 1.00 16.48 ? 464 ARG A CZ 1 ATOM 2510 N NH1 . ARG A 1 158 ? 12.954 186.843 20.285 1.00 20.84 ? 464 ARG A NH1 1 ATOM 2511 N NH2 . ARG A 1 158 ? 13.530 186.140 18.181 1.00 21.17 ? 464 ARG A NH2 1 ATOM 2512 H H . ARG A 1 158 ? 12.392 192.940 19.475 1.00 18.68 ? 464 ARG A H 1 ATOM 2513 H HA . ARG A 1 158 ? 10.492 192.720 17.594 1.00 17.41 ? 464 ARG A HA 1 ATOM 2514 H HB2 . ARG A 1 158 ? 10.787 191.306 20.023 1.00 17.70 ? 464 ARG A HB2 1 ATOM 2515 H HB3 . ARG A 1 158 ? 9.650 190.997 18.962 1.00 17.70 ? 464 ARG A HB3 1 ATOM 2516 H HG2 . ARG A 1 158 ? 11.147 190.161 17.504 1.00 26.86 ? 464 ARG A HG2 1 ATOM 2517 H HG3 . ARG A 1 158 ? 12.366 190.652 18.408 1.00 26.86 ? 464 ARG A HG3 1 ATOM 2518 H HD2 . ARG A 1 158 ? 11.832 189.099 20.050 1.00 24.85 ? 464 ARG A HD2 1 ATOM 2519 H HD3 . ARG A 1 158 ? 10.507 188.679 19.265 1.00 24.85 ? 464 ARG A HD3 1 ATOM 2520 H HE . ARG A 1 158 ? 12.169 188.030 17.584 1.00 19.56 ? 464 ARG A HE 1 ATOM 2521 H HH11 . ARG A 1 158 ? 12.538 187.390 20.803 1.00 25.01 ? 464 ARG A HH11 1 ATOM 2522 H HH12 . ARG A 1 158 ? 13.413 186.198 20.621 1.00 25.01 ? 464 ARG A HH12 1 ATOM 2523 H HH21 . ARG A 1 158 ? 13.484 186.234 17.327 1.00 25.40 ? 464 ARG A HH21 1 ATOM 2524 H HH22 . ARG A 1 158 ? 13.988 185.495 18.518 1.00 25.40 ? 464 ARG A HH22 1 ATOM 2525 N N . TYR A 1 159 ? 9.901 194.004 20.453 1.00 15.42 ? 465 TYR A N 1 ATOM 2526 C CA . TYR A 1 159 ? 8.963 194.714 21.318 1.00 18.88 ? 465 TYR A CA 1 ATOM 2527 C C . TYR A 1 159 ? 9.677 195.859 22.027 1.00 17.97 ? 465 TYR A C 1 ATOM 2528 O O . TYR A 1 159 ? 10.779 195.677 22.556 1.00 14.31 ? 465 TYR A O 1 ATOM 2529 C CB . TYR A 1 159 ? 8.364 193.764 22.365 1.00 21.46 ? 465 TYR A CB 1 ATOM 2530 C CG . TYR A 1 159 ? 7.881 192.467 21.784 1.00 15.32 ? 465 TYR A CG 1 ATOM 2531 C CD1 . TYR A 1 159 ? 6.675 192.407 21.110 1.00 18.35 ? 465 TYR A CD1 1 ATOM 2532 C CD2 . TYR A 1 159 ? 8.622 191.304 21.910 1.00 20.21 ? 465 TYR A CD2 1 ATOM 2533 C CE1 . TYR A 1 159 ? 6.224 191.230 20.557 1.00 26.55 ? 465 TYR A CE1 1 ATOM 2534 C CE2 . TYR A 1 159 ? 8.168 190.098 21.362 1.00 18.72 ? 465 TYR A CE2 1 ATOM 2535 C CZ . TYR A 1 159 ? 6.971 190.071 20.686 1.00 24.86 ? 465 TYR A CZ 1 ATOM 2536 O OH . TYR A 1 159 ? 6.532 188.885 20.134 1.00 23.16 ? 465 TYR A OH 1 ATOM 2537 H H . TYR A 1 159 ? 10.669 193.889 20.822 1.00 18.50 ? 465 TYR A H 1 ATOM 2538 H HA . TYR A 1 159 ? 8.242 195.082 20.784 1.00 22.66 ? 465 TYR A HA 1 ATOM 2539 H HB2 . TYR A 1 159 ? 9.042 193.560 23.028 1.00 25.76 ? 465 TYR A HB2 1 ATOM 2540 H HB3 . TYR A 1 159 ? 7.609 194.200 22.789 1.00 25.76 ? 465 TYR A HB3 1 ATOM 2541 H HD1 . TYR A 1 159 ? 6.168 193.180 21.012 1.00 22.03 ? 465 TYR A HD1 1 ATOM 2542 H HD2 . TYR A 1 159 ? 9.434 191.325 22.362 1.00 24.25 ? 465 TYR A HD2 1 ATOM 2543 H HE1 . TYR A 1 159 ? 5.413 191.211 20.103 1.00 31.86 ? 465 TYR A HE1 1 ATOM 2544 H HE2 . TYR A 1 159 ? 8.677 189.324 21.446 1.00 22.46 ? 465 TYR A HE2 1 ATOM 2545 H HH . TYR A 1 159 ? 7.085 188.273 20.292 1.00 27.79 ? 465 TYR A HH 1 ATOM 2546 N N . CYS A 1 160 ? 9.055 197.030 22.044 1.00 16.75 ? 466 CYS A N 1 ATOM 2547 C CA A CYS A 1 160 ? 9.627 198.166 22.742 0.53 21.47 ? 466 CYS A CA 1 ATOM 2548 C CA B CYS A 1 160 ? 9.583 198.215 22.706 0.47 21.80 ? 466 CYS A CA 1 ATOM 2549 C C . CYS A 1 160 ? 8.767 198.506 23.953 1.00 15.29 ? 466 CYS A C 1 ATOM 2550 O O . CYS A 1 160 ? 7.554 198.286 23.974 1.00 13.31 ? 466 CYS A O 1 ATOM 2551 C CB A CYS A 1 160 ? 9.786 199.375 21.804 0.53 19.73 ? 466 CYS A CB 1 ATOM 2552 C CB B CYS A 1 160 ? 9.525 199.455 21.808 0.47 19.48 ? 466 CYS A CB 1 ATOM 2553 S SG A CYS A 1 160 ? 10.964 199.057 20.456 0.53 10.71 ? 466 CYS A SG 1 ATOM 2554 S SG B CYS A 1 160 ? 9.834 199.172 20.080 0.47 16.20 ? 466 CYS A SG 1 ATOM 2555 H H A CYS A 1 160 ? 8.302 197.190 21.660 0.53 20.10 ? 466 CYS A H 1 ATOM 2556 H H B CYS A 1 160 ? 8.296 197.167 21.664 0.47 20.10 ? 466 CYS A H 1 ATOM 2557 H HA A CYS A 1 160 ? 10.509 197.923 23.063 0.53 25.76 ? 466 CYS A HA 1 ATOM 2558 H HA B CYS A 1 160 ? 10.505 198.061 22.965 0.47 26.16 ? 466 CYS A HA 1 ATOM 2559 H HB2 A CYS A 1 160 ? 8.925 199.585 21.409 0.53 23.68 ? 466 CYS A HB2 1 ATOM 2560 H HB2 B CYS A 1 160 ? 8.642 199.847 21.885 0.47 23.37 ? 466 CYS A HB2 1 ATOM 2561 H HB3 A CYS A 1 160 ? 10.111 200.132 22.316 0.53 23.68 ? 466 CYS A HB3 1 ATOM 2562 H HB3 B CYS A 1 160 ? 10.189 200.090 22.121 0.47 23.37 ? 466 CYS A HB3 1 ATOM 2563 H HG B CYS A 1 160 ? 10.932 198.708 19.950 0.47 19.45 ? 466 CYS A HG 1 ATOM 2564 N N . PHE A 1 161 ? 9.429 199.020 24.971 1.00 16.31 ? 467 PHE A N 1 ATOM 2565 C CA . PHE A 1 161 ? 8.759 199.447 26.186 1.00 18.74 ? 467 PHE A CA 1 ATOM 2566 C C . PHE A 1 161 ? 9.212 200.844 26.580 1.00 12.32 ? 467 PHE A C 1 ATOM 2567 O O . PHE A 1 161 ? 10.401 201.168 26.536 1.00 13.10 ? 467 PHE A O 1 ATOM 2568 C CB . PHE A 1 161 ? 9.026 198.442 27.314 1.00 17.99 ? 467 PHE A CB 1 ATOM 2569 C CG . PHE A 1 161 ? 8.423 197.101 27.052 1.00 16.46 ? 467 PHE A CG 1 ATOM 2570 C CD1 . PHE A 1 161 ? 9.065 196.185 26.238 1.00 15.60 ? 467 PHE A CD1 1 ATOM 2571 C CD2 . PHE A 1 161 ? 7.193 196.768 27.584 1.00 19.03 ? 467 PHE A CD2 1 ATOM 2572 C CE1 . PHE A 1 161 ? 8.496 194.955 25.989 1.00 19.54 ? 467 PHE A CE1 1 ATOM 2573 C CE2 . PHE A 1 161 ? 6.624 195.531 27.338 1.00 19.54 ? 467 PHE A CE2 1 ATOM 2574 C CZ . PHE A 1 161 ? 7.275 194.628 26.543 1.00 17.47 ? 467 PHE A CZ 1 ATOM 2575 H H . PHE A 1 161 ? 10.281 199.134 24.985 1.00 19.57 ? 467 PHE A H 1 ATOM 2576 H HA . PHE A 1 161 ? 7.803 199.475 26.028 1.00 22.48 ? 467 PHE A HA 1 ATOM 2577 H HB2 . PHE A 1 161 ? 9.984 198.325 27.413 1.00 21.59 ? 467 PHE A HB2 1 ATOM 2578 H HB3 . PHE A 1 161 ? 8.647 198.784 28.138 1.00 21.59 ? 467 PHE A HB3 1 ATOM 2579 H HD1 . PHE A 1 161 ? 9.891 196.396 25.866 1.00 18.71 ? 467 PHE A HD1 1 ATOM 2580 H HD2 . PHE A 1 161 ? 6.749 197.377 28.129 1.00 22.84 ? 467 PHE A HD2 1 ATOM 2581 H HE1 . PHE A 1 161 ? 8.938 194.340 25.449 1.00 23.44 ? 467 PHE A HE1 1 ATOM 2582 H HE2 . PHE A 1 161 ? 5.799 195.316 27.709 1.00 23.45 ? 467 PHE A HE2 1 ATOM 2583 H HZ . PHE A 1 161 ? 6.893 193.798 26.371 1.00 20.97 ? 467 PHE A HZ 1 ATOM 2584 N N . SER A 1 162 ? 8.250 201.667 26.947 1.00 14.99 ? 468 SER A N 1 ATOM 2585 C CA . SER A 1 162 ? 8.507 203.000 27.458 1.00 19.75 ? 468 SER A CA 1 ATOM 2586 C C . SER A 1 162 ? 8.274 203.028 28.966 1.00 19.39 ? 468 SER A C 1 ATOM 2587 O O . SER A 1 162 ? 7.443 202.279 29.495 1.00 20.79 ? 468 SER A O 1 ATOM 2588 C CB . SER A 1 162 ? 7.602 204.025 26.772 1.00 21.18 ? 468 SER A CB 1 ATOM 2589 O OG . SER A 1 162 ? 6.248 203.811 27.132 1.00 24.72 ? 468 SER A OG 1 ATOM 2590 H H . SER A 1 162 ? 7.413 201.470 26.910 1.00 17.99 ? 468 SER A H 1 ATOM 2591 H HA . SER A 1 162 ? 9.430 203.240 27.284 1.00 23.70 ? 468 SER A HA 1 ATOM 2592 H HB2 . SER A 1 162 ? 7.867 204.916 27.048 1.00 25.41 ? 468 SER A HB2 1 ATOM 2593 H HB3 . SER A 1 162 ? 7.693 203.934 25.810 1.00 25.41 ? 468 SER A HB3 1 ATOM 2594 H HG . SER A 1 162 ? 6.008 203.040 26.900 1.00 29.66 ? 468 SER A HG 1 ATOM 2595 N N . VAL A 1 163 ? 9.024 203.899 29.651 1.00 12.99 ? 469 VAL A N 1 ATOM 2596 C CA . VAL A 1 163 ? 8.835 204.175 31.074 1.00 26.17 ? 469 VAL A CA 1 ATOM 2597 C C . VAL A 1 163 ? 8.852 205.681 31.294 1.00 23.18 ? 469 VAL A C 1 ATOM 2598 O O . VAL A 1 163 ? 9.462 206.427 30.524 1.00 24.44 ? 469 VAL A O 1 ATOM 2599 C CB . VAL A 1 163 ? 9.916 203.521 31.959 1.00 18.27 ? 469 VAL A CB 1 ATOM 2600 C CG1 . VAL A 1 163 ? 9.993 202.051 31.701 1.00 16.05 ? 469 VAL A CG1 1 ATOM 2601 C CG2 . VAL A 1 163 ? 11.279 204.175 31.747 1.00 14.76 ? 469 VAL A CG2 1 ATOM 2602 H H . VAL A 1 163 ? 9.664 204.352 29.300 1.00 15.59 ? 469 VAL A H 1 ATOM 2603 H HA . VAL A 1 163 ? 7.970 203.837 31.353 1.00 31.41 ? 469 VAL A HA 1 ATOM 2604 H HB . VAL A 1 163 ? 9.672 203.644 32.890 1.00 21.93 ? 469 VAL A HB 1 ATOM 2605 H HG11 . VAL A 1 163 ? 10.678 201.666 32.269 1.00 19.26 ? 469 VAL A HG11 1 ATOM 2606 H HG12 . VAL A 1 163 ? 9.132 201.650 31.901 1.00 19.26 ? 469 VAL A HG12 1 ATOM 2607 H HG13 . VAL A 1 163 ? 10.216 201.906 30.768 1.00 19.26 ? 469 VAL A HG13 1 ATOM 2608 H HG21 . VAL A 1 163 ? 11.931 203.738 32.318 1.00 17.72 ? 469 VAL A HG21 1 ATOM 2609 H HG22 . VAL A 1 163 ? 11.535 204.075 30.816 1.00 17.72 ? 469 VAL A HG22 1 ATOM 2610 H HG23 . VAL A 1 163 ? 11.217 205.115 31.974 1.00 17.72 ? 469 VAL A HG23 1 ATOM 2611 N N . ASN A 1 164 ? 8.189 206.127 32.363 1.00 23.42 ? 470 ASN A N 1 ATOM 2612 C CA . ASN A 1 164 ? 8.273 207.525 32.748 1.00 26.68 ? 470 ASN A CA 1 ATOM 2613 C C . ASN A 1 164 ? 9.537 207.749 33.592 1.00 26.22 ? 470 ASN A C 1 ATOM 2614 O O . ASN A 1 164 ? 10.281 206.815 33.906 1.00 22.17 ? 470 ASN A O 1 ATOM 2615 C CB . ASN A 1 164 ? 6.972 207.967 33.439 1.00 28.23 ? 470 ASN A CB 1 ATOM 2616 C CG . ASN A 1 164 ? 6.761 207.362 34.820 1.00 38.58 ? 470 ASN A CG 1 ATOM 2617 O OD1 . ASN A 1 164 ? 7.679 206.819 35.440 1.00 38.90 ? 470 ASN A OD1 1 ATOM 2618 N ND2 . ASN A 1 164 ? 5.515 207.476 35.315 1.00 44.18 ? 470 ASN A ND2 1 ATOM 2619 H H . ASN A 1 164 ? 7.692 205.644 32.871 1.00 28.10 ? 470 ASN A H 1 ATOM 2620 H HA . ASN A 1 164 ? 8.367 208.059 31.943 1.00 32.02 ? 470 ASN A HA 1 ATOM 2621 H HB2 . ASN A 1 164 ? 6.984 208.932 33.538 1.00 33.88 ? 470 ASN A HB2 1 ATOM 2622 H HB3 . ASN A 1 164 ? 6.221 207.705 32.884 1.00 33.88 ? 470 ASN A HB3 1 ATOM 2623 H HD21 . ASN A 1 164 ? 4.922 207.885 34.846 1.00 53.02 ? 470 ASN A HD21 1 ATOM 2624 N N . ASN A 1 165 ? 9.811 209.007 33.932 1.00 27.20 ? 471 ASN A N 1 ATOM 2625 C CA . ASN A 1 165 ? 11.139 209.343 34.442 1.00 25.62 ? 471 ASN A CA 1 ATOM 2626 C C . ASN A 1 165 ? 11.349 208.942 35.901 1.00 24.87 ? 471 ASN A C 1 ATOM 2627 O O . ASN A 1 165 ? 12.478 209.027 36.396 1.00 24.26 ? 471 ASN A O 1 ATOM 2628 C CB . ASN A 1 165 ? 11.420 210.844 34.254 1.00 34.16 ? 471 ASN A CB 1 ATOM 2629 C CG . ASN A 1 165 ? 10.328 211.730 34.819 1.00 44.19 ? 471 ASN A CG 1 ATOM 2630 O OD1 . ASN A 1 165 ? 9.439 211.267 35.523 1.00 48.15 ? 471 ASN A OD1 1 ATOM 2631 N ND2 . ASN A 1 165 ? 10.383 213.018 34.492 1.00 74.68 ? 471 ASN A ND2 1 ATOM 2632 H H . ASN A 1 165 ? 9.263 209.667 33.878 1.00 32.64 ? 471 ASN A H 1 ATOM 2633 H HA . ASN A 1 165 ? 11.795 208.860 33.916 1.00 30.75 ? 471 ASN A HA 1 ATOM 2634 H HB2 . ASN A 1 165 ? 12.250 211.067 34.705 1.00 40.99 ? 471 ASN A HB2 1 ATOM 2635 H HB3 . ASN A 1 165 ? 11.498 211.033 33.306 1.00 40.99 ? 471 ASN A HB3 1 ATOM 2636 H HD21 . ASN A 1 165 ? 9.786 213.563 34.787 1.00 89.61 ? 471 ASN A HD21 1 ATOM 2637 H HD22 . ASN A 1 165 ? 11.015 213.307 33.985 1.00 89.61 ? 471 ASN A HD22 1 ATOM 2638 N N . THR A 1 166 ? 10.319 208.481 36.594 1.00 20.51 ? 472 THR A N 1 ATOM 2639 C CA . THR A 1 166 ? 10.502 207.953 37.934 1.00 27.49 ? 472 THR A CA 1 ATOM 2640 C C . THR A 1 166 ? 10.761 206.450 37.937 1.00 24.70 ? 472 THR A C 1 ATOM 2641 O O . THR A 1 166 ? 10.879 205.860 39.018 1.00 25.32 ? 472 THR A O 1 ATOM 2642 C CB . THR A 1 166 ? 9.284 208.283 38.804 1.00 30.85 ? 472 THR A CB 1 ATOM 2643 O OG1 . THR A 1 166 ? 8.100 207.738 38.215 1.00 30.31 ? 472 THR A OG1 1 ATOM 2644 C CG2 . THR A 1 166 ? 9.125 209.819 38.963 1.00 29.46 ? 472 THR A CG2 1 ATOM 2645 H H . THR A 1 166 ? 9.507 208.464 36.311 1.00 24.62 ? 472 THR A H 1 ATOM 2646 H HA . THR A 1 166 ? 11.273 208.384 38.333 1.00 32.99 ? 472 THR A HA 1 ATOM 2647 H HB . THR A 1 166 ? 9.407 207.898 39.686 1.00 37.03 ? 472 THR A HB 1 ATOM 2648 H HG1 . THR A 1 166 ? 7.984 208.063 37.449 1.00 36.37 ? 472 THR A HG1 1 ATOM 2649 H HG21 . THR A 1 166 ? 8.352 210.017 39.515 1.00 35.35 ? 472 THR A HG21 1 ATOM 2650 H HG22 . THR A 1 166 ? 9.915 210.192 39.382 1.00 35.35 ? 472 THR A HG22 1 ATOM 2651 H HG23 . THR A 1 166 ? 9.005 210.231 38.093 1.00 35.35 ? 472 THR A HG23 1 ATOM 2652 N N . PHE A 1 167 ? 10.899 205.831 36.765 1.00 21.17 ? 473 PHE A N 1 ATOM 2653 C CA . PHE A 1 167 ? 11.075 204.384 36.695 1.00 22.72 ? 473 PHE A CA 1 ATOM 2654 C C . PHE A 1 167 ? 12.372 203.926 37.348 1.00 20.22 ? 473 PHE A C 1 ATOM 2655 O O . PHE A 1 167 ? 13.440 204.503 37.120 1.00 18.21 ? 473 PHE A O 1 ATOM 2656 C CB . PHE A 1 167 ? 11.067 203.903 35.251 1.00 18.64 ? 473 PHE A CB 1 ATOM 2657 C CG . PHE A 1 167 ? 11.259 202.416 35.117 1.00 18.47 ? 473 PHE A CG 1 ATOM 2658 C CD1 . PHE A 1 167 ? 10.231 201.543 35.414 1.00 16.75 ? 473 PHE A CD1 1 ATOM 2659 C CD2 . PHE A 1 167 ? 12.469 201.897 34.715 1.00 17.08 ? 473 PHE A CD2 1 ATOM 2660 C CE1 . PHE A 1 167 ? 10.406 200.180 35.281 1.00 21.65 ? 473 PHE A CE1 1 ATOM 2661 C CE2 . PHE A 1 167 ? 12.650 200.537 34.589 1.00 17.00 ? 473 PHE A CE2 1 ATOM 2662 C CZ . PHE A 1 167 ? 11.614 199.680 34.871 1.00 17.97 ? 473 PHE A CZ 1 ATOM 2663 H H . PHE A 1 167 ? 10.894 206.224 36.000 1.00 25.41 ? 473 PHE A H 1 ATOM 2664 H HA . PHE A 1 167 ? 10.339 203.955 37.158 1.00 27.26 ? 473 PHE A HA 1 ATOM 2665 H HB2 . PHE A 1 167 ? 10.214 204.131 34.849 1.00 22.37 ? 473 PHE A HB2 1 ATOM 2666 H HB3 . PHE A 1 167 ? 11.786 204.341 34.770 1.00 22.37 ? 473 PHE A HB3 1 ATOM 2667 H HD1 . PHE A 1 167 ? 9.406 201.877 35.685 1.00 20.10 ? 473 PHE A HD1 1 ATOM 2668 H HD2 . PHE A 1 167 ? 13.171 202.473 34.516 1.00 20.50 ? 473 PHE A HD2 1 ATOM 2669 H HE1 . PHE A 1 167 ? 9.706 199.601 35.479 1.00 25.98 ? 473 PHE A HE1 1 ATOM 2670 H HE2 . PHE A 1 167 ? 13.471 200.200 34.311 1.00 20.40 ? 473 PHE A HE2 1 ATOM 2671 H HZ . PHE A 1 167 ? 11.735 198.761 34.791 1.00 21.57 ? 473 PHE A HZ 1 ATOM 2672 N N . CYS A 1 168 ? 12.269 202.858 38.147 1.00 16.64 ? 474 CYS A N 1 ATOM 2673 C CA . CYS A 1 168 ? 13.428 202.108 38.632 1.00 16.44 ? 474 CYS A CA 1 ATOM 2674 C C . CYS A 1 168 ? 12.987 200.647 38.610 1.00 21.18 ? 474 CYS A C 1 ATOM 2675 O O . CYS A 1 168 ? 11.892 200.322 39.130 1.00 17.22 ? 474 CYS A O 1 ATOM 2676 C CB . CYS A 1 168 ? 13.876 202.524 40.041 1.00 20.10 ? 474 CYS A CB 1 ATOM 2677 S SG . CYS A 1 168 ? 15.366 201.691 40.650 1.00 18.26 ? 474 CYS A SG 1 ATOM 2678 H H . CYS A 1 168 ? 11.519 202.544 38.426 1.00 19.97 ? 474 CYS A H 1 ATOM 2679 H HA . CYS A 1 168 ? 14.172 202.221 38.021 1.00 19.73 ? 474 CYS A HA 1 ATOM 2680 H HB2 . CYS A 1 168 ? 14.054 203.477 40.039 1.00 24.12 ? 474 CYS A HB2 1 ATOM 2681 H HB3 . CYS A 1 168 ? 13.157 202.329 40.663 1.00 24.12 ? 474 CYS A HB3 1 ATOM 2682 N N . PRO A 1 169 ? 13.786 199.747 38.032 1.00 12.02 ? 475 PRO A N 1 ATOM 2683 C CA . PRO A 1 169 ? 13.420 198.328 37.998 1.00 18.04 ? 475 PRO A CA 1 ATOM 2684 C C . PRO A 1 169 ? 13.798 197.501 39.229 1.00 17.81 ? 475 PRO A C 1 ATOM 2685 O O . PRO A 1 169 ? 13.494 196.308 39.245 1.00 19.55 ? 475 PRO A O 1 ATOM 2686 C CB . PRO A 1 169 ? 14.201 197.845 36.774 1.00 19.82 ? 475 PRO A CB 1 ATOM 2687 C CG . PRO A 1 169 ? 15.471 198.625 36.851 1.00 17.68 ? 475 PRO A CG 1 ATOM 2688 C CD . PRO A 1 169 ? 15.108 199.970 37.425 1.00 12.55 ? 475 PRO A CD 1 ATOM 2689 H HA . PRO A 1 169 ? 12.470 198.231 37.828 1.00 21.65 ? 475 PRO A HA 1 ATOM 2690 H HB2 . PRO A 1 169 ? 14.373 196.892 36.843 1.00 23.79 ? 475 PRO A HB2 1 ATOM 2691 H HB3 . PRO A 1 169 ? 13.712 198.054 35.963 1.00 23.79 ? 475 PRO A HB3 1 ATOM 2692 H HG2 . PRO A 1 169 ? 16.097 198.166 37.432 1.00 21.22 ? 475 PRO A HG2 1 ATOM 2693 H HG3 . PRO A 1 169 ? 15.843 198.725 35.961 1.00 21.22 ? 475 PRO A HG3 1 ATOM 2694 H HD2 . PRO A 1 169 ? 15.751 200.232 38.103 1.00 15.05 ? 475 PRO A HD2 1 ATOM 2695 H HD3 . PRO A 1 169 ? 15.048 200.633 36.719 1.00 15.05 ? 475 PRO A HD3 1 ATOM 2696 N N . CYS A 1 170 ? 14.439 198.050 40.257 1.00 16.59 ? 476 CYS A N 1 ATOM 2697 C CA . CYS A 1 170 ? 14.897 197.243 41.393 1.00 24.28 ? 476 CYS A CA 1 ATOM 2698 C C . CYS A 1 170 ? 13.944 197.322 42.583 1.00 20.95 ? 476 CYS A C 1 ATOM 2699 O O . CYS A 1 170 ? 13.396 198.384 42.895 1.00 16.32 ? 476 CYS A O 1 ATOM 2700 C CB . CYS A 1 170 ? 16.287 197.677 41.871 1.00 19.53 ? 476 CYS A CB 1 ATOM 2701 S SG . CYS A 1 170 ? 17.596 197.326 40.720 1.00 26.18 ? 476 CYS A SG 1 ATOM 2702 H H . CYS A 1 170 ? 14.623 198.888 40.324 1.00 19.91 ? 476 CYS A H 1 ATOM 2703 H HA . CYS A 1 170 ? 14.953 196.315 41.117 1.00 29.13 ? 476 CYS A HA 1 ATOM 2704 H HB2 . CYS A 1 170 ? 16.278 198.635 42.025 1.00 23.43 ? 476 CYS A HB2 1 ATOM 2705 H HB3 . CYS A 1 170 ? 16.490 197.214 42.699 1.00 23.43 ? 476 CYS A HB3 1 ATOM 2706 N N . ALA A 1 171 ? 13.790 196.195 43.268 1.00 16.21 ? 477 ALA A N 1 ATOM 2707 C CA . ALA A 1 171 ? 13.032 196.148 44.514 1.00 24.39 ? 477 ALA A CA 1 ATOM 2708 C C . ALA A 1 171 ? 13.753 196.883 45.648 1.00 14.36 ? 477 ALA A C 1 ATOM 2709 O O . ALA A 1 171 ? 14.986 196.952 45.704 1.00 13.92 ? 477 ALA A O 1 ATOM 2710 C CB . ALA A 1 171 ? 12.784 194.701 44.937 1.00 17.26 ? 477 ALA A CB 1 ATOM 2711 H H . ALA A 1 171 ? 14.117 195.436 43.030 1.00 19.45 ? 477 ALA A H 1 ATOM 2712 H HA . ALA A 1 171 ? 12.172 196.575 44.378 1.00 29.27 ? 477 ALA A HA 1 ATOM 2713 H HB1 . ALA A 1 171 ? 12.280 194.697 45.766 1.00 20.71 ? 477 ALA A HB1 1 ATOM 2714 H HB2 . ALA A 1 171 ? 12.280 194.251 44.241 1.00 20.71 ? 477 ALA A HB2 1 ATOM 2715 H HB3 . ALA A 1 171 ? 13.638 194.259 45.067 1.00 20.71 ? 477 ALA A HB3 1 ATOM 2716 N N . LYS A 1 172 ? 12.969 197.424 46.556 1.00 14.71 ? 478 LYS A N 1 ATOM 2717 C CA . LYS A 1 172 ? 13.538 198.184 47.672 1.00 17.26 ? 478 LYS A CA 1 ATOM 2718 C C . LYS A 1 172 ? 14.200 197.223 48.653 1.00 14.30 ? 478 LYS A C 1 ATOM 2719 O O . LYS A 1 172 ? 13.580 196.241 49.053 1.00 14.30 ? 478 LYS A O 1 ATOM 2720 C CB . LYS A 1 172 ? 12.464 198.998 48.384 1.00 15.22 ? 478 LYS A CB 1 ATOM 2721 C CG . LYS A 1 172 ? 13.037 200.034 49.350 1.00 22.74 ? 478 LYS A CG 1 ATOM 2722 C CD . LYS A 1 172 ? 12.007 201.056 49.791 1.00 20.27 ? 478 LYS A CD 1 ATOM 2723 C CE . LYS A 1 172 ? 12.673 202.237 50.497 1.00 24.43 ? 478 LYS A CE 1 ATOM 2724 N NZ . LYS A 1 172 ? 13.247 201.820 51.816 1.00 22.57 ? 478 LYS A NZ 1 ATOM 2725 H H . LYS A 1 172 ? 12.111 197.372 46.559 1.00 17.65 ? 478 LYS A H 1 ATOM 2726 H HA . LYS A 1 172 ? 14.213 198.794 47.336 1.00 20.71 ? 478 LYS A HA 1 ATOM 2727 H HB2 . LYS A 1 172 ? 11.934 199.469 47.722 1.00 18.26 ? 478 LYS A HB2 1 ATOM 2728 H HB3 . LYS A 1 172 ? 11.898 198.396 48.893 1.00 18.26 ? 478 LYS A HB3 1 ATOM 2729 H HG2 . LYS A 1 172 ? 13.368 199.580 50.141 1.00 27.28 ? 478 LYS A HG2 1 ATOM 2730 H HG3 . LYS A 1 172 ? 13.762 200.508 48.912 1.00 27.28 ? 478 LYS A HG3 1 ATOM 2731 H HD2 . LYS A 1 172 ? 11.534 201.392 49.014 1.00 24.32 ? 478 LYS A HD2 1 ATOM 2732 H HD3 . LYS A 1 172 ? 11.386 200.640 50.410 1.00 24.32 ? 478 LYS A HD3 1 ATOM 2733 H HE2 . LYS A 1 172 ? 13.394 202.577 49.944 1.00 29.32 ? 478 LYS A HE2 1 ATOM 2734 H HE3 . LYS A 1 172 ? 12.014 202.930 50.657 1.00 29.32 ? 478 LYS A HE3 1 ATOM 2735 H HZ1 . LYS A 1 172 ? 13.631 202.518 52.214 1.00 27.08 ? 478 LYS A HZ1 1 ATOM 2736 H HZ2 . LYS A 1 172 ? 12.603 201.505 52.343 1.00 27.08 ? 478 LYS A HZ2 1 ATOM 2737 H HZ3 . LYS A 1 172 ? 13.858 201.185 51.695 1.00 27.08 ? 478 LYS A HZ3 1 ATOM 2738 N N . PRO A 1 173 ? 15.459 197.442 49.019 1.00 12.09 ? 479 PRO A N 1 ATOM 2739 C CA . PRO A 1 173 ? 16.123 196.516 49.944 1.00 17.21 ? 479 PRO A CA 1 ATOM 2740 C C . PRO A 1 173 ? 15.369 196.300 51.258 1.00 19.82 ? 479 PRO A C 1 ATOM 2741 O O . PRO A 1 173 ? 15.350 195.176 51.779 1.00 24.03 ? 479 PRO A O 1 ATOM 2742 C CB . PRO A 1 173 ? 17.484 197.189 50.160 1.00 20.92 ? 479 PRO A CB 1 ATOM 2743 C CG . PRO A 1 173 ? 17.722 197.929 48.921 1.00 22.09 ? 479 PRO A CG 1 ATOM 2744 C CD . PRO A 1 173 ? 16.396 198.439 48.481 1.00 17.85 ? 479 PRO A CD 1 ATOM 2745 H HA . PRO A 1 173 ? 16.260 195.658 49.513 1.00 20.66 ? 479 PRO A HA 1 ATOM 2746 H HB2 . PRO A 1 173 ? 17.437 197.792 50.919 1.00 25.10 ? 479 PRO A HB2 1 ATOM 2747 H HB3 . PRO A 1 173 ? 18.168 196.514 50.296 1.00 25.10 ? 479 PRO A HB3 1 ATOM 2748 H HG2 . PRO A 1 173 ? 18.329 198.666 49.095 1.00 26.51 ? 479 PRO A HG2 1 ATOM 2749 H HG3 . PRO A 1 173 ? 18.095 197.332 48.254 1.00 26.51 ? 479 PRO A HG3 1 ATOM 2750 H HD2 . PRO A 1 173 ? 16.222 199.311 48.870 1.00 21.42 ? 479 PRO A HD2 1 ATOM 2751 H HD3 . PRO A 1 173 ? 16.346 198.463 47.513 1.00 21.42 ? 479 PRO A HD3 1 ATOM 2752 N N . SER A 1 174 ? 14.730 197.337 51.799 1.00 16.75 ? 480 SER A N 1 ATOM 2753 C CA . SER A 1 174 ? 13.963 197.159 53.031 1.00 23.69 ? 480 SER A CA 1 ATOM 2754 C C . SER A 1 174 ? 12.791 196.218 52.807 1.00 26.80 ? 480 SER A C 1 ATOM 2755 O O . SER A 1 174 ? 12.420 195.451 53.705 1.00 23.24 ? 480 SER A O 1 ATOM 2756 C CB . SER A 1 174 ? 13.461 198.507 53.563 1.00 22.90 ? 480 SER A CB 1 ATOM 2757 O OG . SER A 1 174 ? 14.538 199.337 53.940 1.00 16.93 ? 480 SER A OG 1 ATOM 2758 H H . SER A 1 174 ? 14.723 198.136 51.480 1.00 20.10 ? 480 SER A H 1 ATOM 2759 H HA . SER A 1 174 ? 14.537 196.766 53.706 1.00 28.43 ? 480 SER A HA 1 ATOM 2760 H HB2 . SER A 1 174 ? 12.951 198.950 52.867 1.00 27.48 ? 480 SER A HB2 1 ATOM 2761 H HB3 . SER A 1 174 ? 12.899 198.351 54.337 1.00 27.48 ? 480 SER A HB3 1 ATOM 2762 H HG . SER A 1 174 ? 14.248 200.071 54.229 1.00 20.31 ? 480 SER A HG 1 ATOM 2763 N N . PHE A 1 175 ? 12.181 196.267 51.618 1.00 20.81 ? 481 PHE A N 1 ATOM 2764 C CA . PHE A 1 175 ? 11.099 195.331 51.346 1.00 21.93 ? 481 PHE A CA 1 ATOM 2765 C C . PHE A 1 175 ? 11.638 193.919 51.233 1.00 22.38 ? 481 PHE A C 1 ATOM 2766 O O . PHE A 1 175 ? 11.011 192.968 51.708 1.00 20.93 ? 481 PHE A O 1 ATOM 2767 C CB . PHE A 1 175 ? 10.341 195.687 50.067 1.00 16.95 ? 481 PHE A CB 1 ATOM 2768 C CG . PHE A 1 175 ? 9.379 194.601 49.638 1.00 28.66 ? 481 PHE A CG 1 ATOM 2769 C CD1 . PHE A 1 175 ? 8.084 194.571 50.125 1.00 24.50 ? 481 PHE A CD1 1 ATOM 2770 C CD2 . PHE A 1 175 ? 9.786 193.590 48.782 1.00 22.55 ? 481 PHE A CD2 1 ATOM 2771 C CE1 . PHE A 1 175 ? 7.209 193.564 49.761 1.00 23.92 ? 481 PHE A CE1 1 ATOM 2772 C CE2 . PHE A 1 175 ? 8.920 192.563 48.429 1.00 29.92 ? 481 PHE A CE2 1 ATOM 2773 C CZ . PHE A 1 175 ? 7.627 192.554 48.915 1.00 28.99 ? 481 PHE A CZ 1 ATOM 2774 H H . PHE A 1 175 ? 12.369 196.810 50.978 1.00 24.97 ? 481 PHE A H 1 ATOM 2775 H HA . PHE A 1 175 ? 10.470 195.354 52.084 1.00 26.31 ? 481 PHE A HA 1 ATOM 2776 H HB2 . PHE A 1 175 ? 9.830 196.498 50.218 1.00 20.33 ? 481 PHE A HB2 1 ATOM 2777 H HB3 . PHE A 1 175 ? 10.978 195.824 49.349 1.00 20.33 ? 481 PHE A HB3 1 ATOM 2778 H HD1 . PHE A 1 175 ? 7.797 195.241 50.704 1.00 29.39 ? 481 PHE A HD1 1 ATOM 2779 H HD2 . PHE A 1 175 ? 10.658 193.585 48.461 1.00 27.07 ? 481 PHE A HD2 1 ATOM 2780 H HE1 . PHE A 1 175 ? 6.340 193.561 50.094 1.00 28.71 ? 481 PHE A HE1 1 ATOM 2781 H HE2 . PHE A 1 175 ? 9.203 191.896 47.847 1.00 35.91 ? 481 PHE A HE2 1 ATOM 2782 H HZ . PHE A 1 175 ? 7.037 191.881 48.663 1.00 34.79 ? 481 PHE A HZ 1 ATOM 2783 N N . ALA A 1 176 ? 12.791 193.763 50.589 1.00 23.17 ? 482 ALA A N 1 ATOM 2784 C CA . ALA A 1 176 ? 13.277 192.427 50.282 1.00 23.97 ? 482 ALA A CA 1 ATOM 2785 C C . ALA A 1 176 ? 13.795 191.709 51.517 1.00 23.79 ? 482 ALA A C 1 ATOM 2786 O O . ALA A 1 176 ? 13.839 190.475 51.530 1.00 24.60 ? 482 ALA A O 1 ATOM 2787 C CB . ALA A 1 176 ? 14.379 192.505 49.234 1.00 16.04 ? 482 ALA A CB 1 ATOM 2788 H H . ALA A 1 176 ? 13.301 194.403 50.323 1.00 27.80 ? 482 ALA A H 1 ATOM 2789 H HA . ALA A 1 176 ? 12.548 191.903 49.913 1.00 28.76 ? 482 ALA A HA 1 ATOM 2790 H HB1 . ALA A 1 176 ? 14.693 191.609 49.039 1.00 19.25 ? 482 ALA A HB1 1 ATOM 2791 H HB2 . ALA A 1 176 ? 14.021 192.913 48.430 1.00 19.25 ? 482 ALA A HB2 1 ATOM 2792 H HB3 . ALA A 1 176 ? 15.107 193.043 49.582 1.00 19.25 ? 482 ALA A HB3 1 ATOM 2793 N N . SER A 1 177 ? 14.163 192.455 52.557 1.00 23.00 ? 483 SER A N 1 ATOM 2794 C CA . SER A 1 177 ? 14.887 191.884 53.685 1.00 30.39 ? 483 SER A CA 1 ATOM 2795 C C . SER A 1 177 ? 14.042 190.924 54.514 1.00 27.41 ? 483 SER A C 1 ATOM 2796 O O . SER A 1 177 ? 14.604 190.129 55.267 1.00 35.30 ? 483 SER A O 1 ATOM 2797 C CB . SER A 1 177 ? 15.417 193.010 54.573 1.00 27.92 ? 483 SER A CB 1 ATOM 2798 O OG . SER A 1 177 ? 14.356 193.850 54.989 1.00 30.68 ? 483 SER A OG 1 ATOM 2799 H H . SER A 1 177 ? 14.003 193.297 52.632 1.00 27.59 ? 483 SER A H 1 ATOM 2800 H HA . SER A 1 177 ? 15.650 191.390 53.346 1.00 36.47 ? 483 SER A HA 1 ATOM 2801 H HB2 . SER A 1 177 ? 15.842 192.624 55.355 1.00 33.51 ? 483 SER A HB2 1 ATOM 2802 H HB3 . SER A 1 177 ? 16.060 193.535 54.070 1.00 33.51 ? 483 SER A HB3 1 ATOM 2803 H HG . SER A 1 177 ? 13.979 194.189 54.319 1.00 36.82 ? 483 SER A HG 1 ATOM 2804 N N . SER A 1 178 ? 12.719 190.984 54.416 1.00 26.84 ? 484 SER A N 1 ATOM 2805 C CA . SER A 1 178 ? 11.858 190.084 55.169 1.00 25.36 ? 484 SER A CA 1 ATOM 2806 C C . SER A 1 178 ? 11.152 189.048 54.291 1.00 26.24 ? 484 SER A C 1 ATOM 2807 O O . SER A 1 178 ? 10.346 188.263 54.805 1.00 24.83 ? 484 SER A O 1 ATOM 2808 C CB . SER A 1 178 ? 10.832 190.900 55.972 1.00 25.27 ? 484 SER A CB 1 ATOM 2809 O OG . SER A 1 178 ? 9.888 191.533 55.133 1.00 34.29 ? 484 SER A OG 1 ATOM 2810 H H . SER A 1 178 ? 12.294 191.540 53.916 1.00 32.21 ? 484 SER A H 1 ATOM 2811 H HA . SER A 1 178 ? 12.405 189.599 55.806 1.00 30.43 ? 484 SER A HA 1 ATOM 2812 H HB2 . SER A 1 178 ? 10.362 190.303 56.575 1.00 30.33 ? 484 SER A HB2 1 ATOM 2813 H HB3 . SER A 1 178 ? 11.302 191.578 56.481 1.00 30.33 ? 484 SER A HB3 1 ATOM 2814 H HG . SER A 1 178 ? 9.469 190.958 54.687 1.00 41.15 ? 484 SER A HG 1 ATOM 2815 N N . CYS A 1 179 ? 11.439 189.013 52.990 1.00 29.40 ? 485 CYS A N 1 ATOM 2816 C CA . CYS A 1 179 ? 10.916 187.960 52.114 1.00 25.88 ? 485 CYS A CA 1 ATOM 2817 C C . CYS A 1 179 ? 11.564 186.623 52.428 1.00 21.64 ? 485 CYS A C 1 ATOM 2818 O O . CYS A 1 179 ? 12.787 186.541 52.566 1.00 27.74 ? 485 CYS A O 1 ATOM 2819 C CB . CYS A 1 179 ? 11.184 188.301 50.648 1.00 29.45 ? 485 CYS A CB 1 ATOM 2820 S SG . CYS A 1 179 ? 10.332 189.752 50.088 1.00 22.21 ? 485 CYS A SG 1 ATOM 2821 H H . CYS A 1 179 ? 11.936 189.588 52.588 1.00 35.28 ? 485 CYS A H 1 ATOM 2822 H HA . CYS A 1 179 ? 9.958 187.877 52.242 1.00 31.05 ? 485 CYS A HA 1 ATOM 2823 H HB2 . CYS A 1 179 ? 12.135 188.451 50.530 1.00 35.34 ? 485 CYS A HB2 1 ATOM 2824 H HB3 . CYS A 1 179 ? 10.897 187.557 50.096 1.00 35.34 ? 485 CYS A HB3 1 ATOM 2825 N N . LYS A 1 180 ? 10.744 185.572 52.523 1.00 22.88 ? 486 LYS A N 1 ATOM 2826 C CA . LYS A 1 180 ? 11.222 184.197 52.639 1.00 22.08 ? 486 LYS A CA 1 ATOM 2827 C C . LYS A 1 180 ? 10.951 183.345 51.409 1.00 20.54 ? 486 LYS A C 1 ATOM 2828 O O . LYS A 1 180 ? 11.742 182.451 51.108 1.00 21.13 ? 486 LYS A O 1 ATOM 2829 C CB . LYS A 1 180 ? 10.581 183.505 53.849 1.00 27.10 ? 486 LYS A CB 1 ATOM 2830 C CG . LYS A 1 180 ? 11.047 184.073 55.188 1.00 30.63 ? 486 LYS A CG 1 ATOM 2831 C CD . LYS A 1 180 ? 10.098 183.711 56.349 1.00 41.17 ? 486 LYS A CD 1 ATOM 2832 C CE . LYS A 1 180 ? 10.452 182.395 57.018 1.00 46.75 ? 486 LYS A CE 1 ATOM 2833 N NZ . LYS A 1 180 ? 9.529 182.088 58.171 1.00 49.57 ? 486 LYS A NZ 1 ATOM 2834 H H . LYS A 1 180 ? 9.886 185.636 52.521 1.00 27.46 ? 486 LYS A H 1 ATOM 2835 H HA . LYS A 1 180 ? 12.182 184.213 52.781 1.00 26.50 ? 486 LYS A HA 1 ATOM 2836 H HB2 . LYS A 1 180 ? 9.618 183.611 53.798 1.00 32.52 ? 486 LYS A HB2 1 ATOM 2837 H HB3 . LYS A 1 180 ? 10.810 182.562 53.829 1.00 32.52 ? 486 LYS A HB3 1 ATOM 2838 H HG2 . LYS A 1 180 ? 11.925 183.716 55.396 1.00 36.76 ? 486 LYS A HG2 1 ATOM 2839 H HG3 . LYS A 1 180 ? 11.088 185.040 55.125 1.00 36.76 ? 486 LYS A HG3 1 ATOM 2840 H HD2 . LYS A 1 180 ? 10.141 184.409 57.022 1.00 49.40 ? 486 LYS A HD2 1 ATOM 2841 H HD3 . LYS A 1 180 ? 9.193 183.638 56.006 1.00 49.40 ? 486 LYS A HD3 1 ATOM 2842 H HE2 . LYS A 1 180 ? 10.376 181.677 56.370 1.00 56.10 ? 486 LYS A HE2 1 ATOM 2843 H HE3 . LYS A 1 180 ? 11.358 182.444 57.359 1.00 56.10 ? 486 LYS A HE3 1 ATOM 2844 H HZ1 . LYS A 1 180 ? 9.758 181.313 58.545 1.00 59.48 ? 486 LYS A HZ1 1 ATOM 2845 H HZ2 . LYS A 1 180 ? 9.584 182.732 58.783 1.00 59.48 ? 486 LYS A HZ2 1 ATOM 2846 H HZ3 . LYS A 1 180 ? 8.689 182.033 57.882 1.00 59.48 ? 486 LYS A HZ3 1 ATOM 2847 N N . SER A 1 181 ? 9.839 183.568 50.724 1.00 16.57 ? 487 SER A N 1 ATOM 2848 C CA . SER A 1 181 ? 9.531 182.882 49.482 1.00 19.54 ? 487 SER A CA 1 ATOM 2849 C C . SER A 1 181 ? 9.567 183.885 48.332 1.00 22.93 ? 487 SER A C 1 ATOM 2850 O O . SER A 1 181 ? 8.844 184.889 48.347 1.00 18.02 ? 487 SER A O 1 ATOM 2851 C CB . SER A 1 181 ? 8.178 182.189 49.582 1.00 18.39 ? 487 SER A CB 1 ATOM 2852 O OG . SER A 1 181 ? 8.252 181.129 50.527 1.00 23.16 ? 487 SER A OG 1 ATOM 2853 H H . SER A 1 181 ? 9.232 184.126 50.967 1.00 19.89 ? 487 SER A H 1 ATOM 2854 H HA . SER A 1 181 ? 10.206 182.206 49.315 1.00 23.45 ? 487 SER A HA 1 ATOM 2855 H HB2 . SER A 1 181 ? 7.511 182.830 49.873 1.00 22.07 ? 487 SER A HB2 1 ATOM 2856 H HB3 . SER A 1 181 ? 7.940 181.827 48.715 1.00 22.07 ? 487 SER A HB3 1 ATOM 2857 H HG . SER A 1 181 ? 7.508 180.744 50.585 1.00 27.79 ? 487 SER A HG 1 ATOM 2858 N N . HIS A 1 182 ? 10.444 183.623 47.367 1.00 15.04 ? 488 HIS A N 1 ATOM 2859 C CA . HIS A 1 182 ? 10.575 184.413 46.151 1.00 23.38 ? 488 HIS A CA 1 ATOM 2860 C C . HIS A 1 182 ? 11.085 185.814 46.477 1.00 25.65 ? 488 HIS A C 1 ATOM 2861 O O . HIS A 1 182 ? 10.555 186.809 45.990 1.00 22.62 ? 488 HIS A O 1 ATOM 2862 C CB . HIS A 1 182 ? 9.256 184.482 45.378 1.00 19.45 ? 488 HIS A CB 1 ATOM 2863 C CG . HIS A 1 182 ? 8.989 183.276 44.546 1.00 21.25 ? 488 HIS A CG 1 ATOM 2864 N ND1 . HIS A 1 182 ? 9.761 182.940 43.455 1.00 27.71 ? 488 HIS A ND1 1 ATOM 2865 C CD2 . HIS A 1 182 ? 8.053 182.304 44.657 1.00 23.55 ? 488 HIS A CD2 1 ATOM 2866 C CE1 . HIS A 1 182 ? 9.308 181.820 42.923 1.00 15.14 ? 488 HIS A CE1 1 ATOM 2867 N NE2 . HIS A 1 182 ? 8.263 181.422 43.624 1.00 18.93 ? 488 HIS A NE2 1 ATOM 2868 H H . HIS A 1 182 ? 10.996 182.964 47.399 1.00 18.04 ? 488 HIS A H 1 ATOM 2869 H HA . HIS A 1 182 ? 11.230 183.989 45.575 1.00 28.06 ? 488 HIS A HA 1 ATOM 2870 H HB2 . HIS A 1 182 ? 8.527 184.573 46.011 1.00 23.34 ? 488 HIS A HB2 1 ATOM 2871 H HB3 . HIS A 1 182 ? 9.278 185.251 44.788 1.00 23.34 ? 488 HIS A HB3 1 ATOM 2872 H HD2 . HIS A 1 182 ? 7.381 182.255 45.298 1.00 28.26 ? 488 HIS A HD2 1 ATOM 2873 H HE1 . HIS A 1 182 ? 9.655 181.394 42.172 1.00 18.17 ? 488 HIS A HE1 1 ATOM 2874 H HE2 . HIS A 1 182 ? 7.801 180.713 43.471 1.00 22.71 ? 488 HIS A HE2 1 ATOM 2875 N N . LYS A 1 183 ? 12.125 185.876 47.305 1.00 17.74 ? 489 LYS A N 1 ATOM 2876 C CA . LYS A 1 183 ? 12.784 187.140 47.570 1.00 20.86 ? 489 LYS A CA 1 ATOM 2877 C C . LYS A 1 183 ? 13.240 187.770 46.252 1.00 21.76 ? 489 LYS A C 1 ATOM 2878 O O . LYS A 1 183 ? 13.946 187.114 45.473 1.00 17.00 ? 489 LYS A O 1 ATOM 2879 C CB . LYS A 1 183 ? 13.993 186.954 48.485 1.00 20.02 ? 489 LYS A CB 1 ATOM 2880 C CG . LYS A 1 183 ? 14.656 188.291 48.865 1.00 24.33 ? 489 LYS A CG 1 ATOM 2881 C CD . LYS A 1 183 ? 16.081 188.122 49.352 1.00 27.01 ? 489 LYS A CD 1 ATOM 2882 C CE . LYS A 1 183 ? 16.149 187.410 50.687 1.00 29.92 ? 489 LYS A CE 1 ATOM 2883 N NZ . LYS A 1 183 ? 15.651 188.245 51.803 1.00 37.19 ? 489 LYS A NZ 1 ATOM 2884 H H . LYS A 1 183 ? 12.462 185.204 47.722 1.00 21.29 ? 489 LYS A H 1 ATOM 2885 H HA . LYS A 1 183 ? 12.161 187.746 48.002 1.00 25.03 ? 489 LYS A HA 1 ATOM 2886 H HB2 . LYS A 1 183 ? 13.707 186.516 49.302 1.00 24.03 ? 489 LYS A HB2 1 ATOM 2887 H HB3 . LYS A 1 183 ? 14.654 186.409 48.029 1.00 24.03 ? 489 LYS A HB3 1 ATOM 2888 H HG2 . LYS A 1 183 ? 14.672 188.869 48.086 1.00 29.20 ? 489 LYS A HG2 1 ATOM 2889 H HG3 . LYS A 1 183 ? 14.143 188.707 49.576 1.00 29.20 ? 489 LYS A HG3 1 ATOM 2890 H HD2 . LYS A 1 183 ? 16.578 187.598 48.705 1.00 32.41 ? 489 LYS A HD2 1 ATOM 2891 H HD3 . LYS A 1 183 ? 16.488 188.997 49.456 1.00 32.41 ? 489 LYS A HD3 1 ATOM 2892 H HE2 . LYS A 1 183 ? 15.605 186.608 50.646 1.00 35.90 ? 489 LYS A HE2 1 ATOM 2893 H HE3 . LYS A 1 183 ? 17.072 187.177 50.875 1.00 35.90 ? 489 LYS A HE3 1 ATOM 2894 H HZ1 . LYS A 1 183 ? 15.706 187.794 52.569 1.00 44.63 ? 489 LYS A HZ1 1 ATOM 2895 H HZ2 . LYS A 1 183 ? 16.138 188.987 51.869 1.00 44.63 ? 489 LYS A HZ2 1 ATOM 2896 H HZ3 . LYS A 1 183 ? 14.801 188.469 51.660 1.00 44.63 ? 489 LYS A HZ3 1 ATOM 2897 N N . PRO A 1 184 ? 12.884 189.022 45.976 1.00 19.18 ? 490 PRO A N 1 ATOM 2898 C CA . PRO A 1 184 ? 13.373 189.668 44.759 1.00 18.93 ? 490 PRO A CA 1 ATOM 2899 C C . PRO A 1 184 ? 14.768 190.219 44.981 1.00 17.01 ? 490 PRO A C 1 ATOM 2900 O O . PRO A 1 184 ? 15.137 190.538 46.121 1.00 19.94 ? 490 PRO A O 1 ATOM 2901 C CB . PRO A 1 184 ? 12.359 190.795 44.532 1.00 21.11 ? 490 PRO A CB 1 ATOM 2902 C CG . PRO A 1 184 ? 11.971 191.206 45.919 1.00 22.62 ? 490 PRO A CG 1 ATOM 2903 C CD . PRO A 1 184 ? 12.030 189.936 46.767 1.00 21.41 ? 490 PRO A CD 1 ATOM 2904 H HA . PRO A 1 184 ? 13.368 189.055 44.008 1.00 22.72 ? 490 PRO A HA 1 ATOM 2905 H HB2 . PRO A 1 184 ? 12.779 191.529 44.056 1.00 25.34 ? 490 PRO A HB2 1 ATOM 2906 H HB3 . PRO A 1 184 ? 11.592 190.457 44.043 1.00 25.34 ? 490 PRO A HB3 1 ATOM 2907 H HG2 . PRO A 1 184 ? 12.601 191.866 46.250 1.00 27.14 ? 490 PRO A HG2 1 ATOM 2908 H HG3 . PRO A 1 184 ? 11.072 191.569 45.911 1.00 27.14 ? 490 PRO A HG3 1 ATOM 2909 H HD2 . PRO A 1 184 ? 12.442 190.122 47.625 1.00 25.69 ? 490 PRO A HD2 1 ATOM 2910 H HD3 . PRO A 1 184 ? 11.142 189.560 46.873 1.00 25.69 ? 490 PRO A HD3 1 ATOM 2911 N N . PRO A 1 185 ? 15.581 190.336 43.934 1.00 16.28 ? 491 PRO A N 1 ATOM 2912 C CA . PRO A 1 185 ? 16.816 191.115 44.063 1.00 20.70 ? 491 PRO A CA 1 ATOM 2913 C C . PRO A 1 185 ? 16.503 192.593 44.293 1.00 17.15 ? 491 PRO A C 1 ATOM 2914 O O . PRO A 1 185 ? 15.451 193.104 43.900 1.00 13.67 ? 491 PRO A O 1 ATOM 2915 C CB . PRO A 1 185 ? 17.532 190.882 42.729 1.00 22.08 ? 491 PRO A CB 1 ATOM 2916 C CG . PRO A 1 185 ? 16.447 190.504 41.776 1.00 25.38 ? 491 PRO A CG 1 ATOM 2917 C CD . PRO A 1 185 ? 15.425 189.767 42.584 1.00 22.49 ? 491 PRO A CD 1 ATOM 2918 H HA . PRO A 1 185 ? 17.361 190.778 44.791 1.00 24.84 ? 491 PRO A HA 1 ATOM 2919 H HB2 . PRO A 1 185 ? 17.971 191.699 42.444 1.00 26.49 ? 491 PRO A HB2 1 ATOM 2920 H HB3 . PRO A 1 185 ? 18.174 190.161 42.823 1.00 26.49 ? 491 PRO A HB3 1 ATOM 2921 H HG2 . PRO A 1 185 ? 16.061 191.306 41.390 1.00 30.46 ? 491 PRO A HG2 1 ATOM 2922 H HG3 . PRO A 1 185 ? 16.810 189.932 41.082 1.00 30.46 ? 491 PRO A HG3 1 ATOM 2923 H HD2 . PRO A 1 185 ? 14.534 189.943 42.243 1.00 26.99 ? 491 PRO A HD2 1 ATOM 2924 H HD3 . PRO A 1 185 ? 15.622 188.817 42.592 1.00 26.99 ? 491 PRO A HD3 1 ATOM 2925 N N . SER A 1 186 ? 17.425 193.279 44.954 1.00 17.02 ? 492 SER A N 1 ATOM 2926 C CA . SER A 1 186 ? 17.161 194.630 45.428 1.00 20.19 ? 492 SER A CA 1 ATOM 2927 C C . SER A 1 186 ? 18.418 195.474 45.327 1.00 15.82 ? 492 SER A C 1 ATOM 2928 O O . SER A 1 186 ? 19.529 194.962 45.197 1.00 16.45 ? 492 SER A O 1 ATOM 2929 C CB . SER A 1 186 ? 16.644 194.630 46.878 1.00 20.02 ? 492 SER A CB 1 ATOM 2930 O OG . SER A 1 186 ? 17.469 193.840 47.722 1.00 16.82 ? 492 SER A OG 1 ATOM 2931 H H . SER A 1 186 ? 18.212 192.986 45.141 1.00 20.43 ? 492 SER A H 1 ATOM 2932 H HA . SER A 1 186 ? 16.481 195.035 44.867 1.00 24.23 ? 492 SER A HA 1 ATOM 2933 H HB2 . SER A 1 186 ? 16.638 195.542 47.209 1.00 24.02 ? 492 SER A HB2 1 ATOM 2934 H HB3 . SER A 1 186 ? 15.744 194.269 46.890 1.00 24.02 ? 492 SER A HB3 1 ATOM 2935 H HG . SER A 1 186 ? 18.253 194.142 47.722 1.00 20.19 ? 492 SER A HG 1 ATOM 2936 N N . ALA A 1 187 ? 18.217 196.788 45.380 1.00 20.70 ? 493 ALA A N 1 ATOM 2937 C CA . ALA A 1 187 ? 19.300 197.760 45.314 1.00 17.44 ? 493 ALA A CA 1 ATOM 2938 C C . ALA A 1 187 ? 18.673 199.121 45.538 1.00 14.43 ? 493 ALA A C 1 ATOM 2939 O O . ALA A 1 187 ? 17.450 199.255 45.571 1.00 16.34 ? 493 ALA A O 1 ATOM 2940 C CB . ALA A 1 187 ? 20.045 197.705 43.980 1.00 23.22 ? 493 ALA A CB 1 ATOM 2941 H H . ALA A 1 187 ? 17.440 197.148 45.456 1.00 24.84 ? 493 ALA A H 1 ATOM 2942 H HA . ALA A 1 187 ? 19.933 197.590 46.029 1.00 20.93 ? 493 ALA A HA 1 ATOM 2943 H HB1 . ALA A 1 187 ? 20.753 198.368 43.987 1.00 27.87 ? 493 ALA A HB1 1 ATOM 2944 H HB2 . ALA A 1 187 ? 20.423 196.818 43.867 1.00 27.87 ? 493 ALA A HB2 1 ATOM 2945 H HB3 . ALA A 1 187 ? 19.421 197.894 43.262 1.00 27.87 ? 493 ALA A HB3 1 ATOM 2946 N N . SER A 1 188 ? 19.515 200.129 45.711 1.00 18.23 ? 494 SER A N 1 ATOM 2947 C CA . SER A 1 188 ? 18.991 201.477 45.854 1.00 23.84 ? 494 SER A CA 1 ATOM 2948 C C . SER A 1 188 ? 18.625 202.007 44.482 1.00 22.63 ? 494 SER A C 1 ATOM 2949 O O . SER A 1 188 ? 19.325 201.755 43.500 1.00 16.16 ? 494 SER A O 1 ATOM 2950 C CB . SER A 1 188 ? 19.999 202.417 46.513 1.00 23.31 ? 494 SER A CB 1 ATOM 2951 O OG . SER A 1 188 ? 21.185 202.504 45.754 1.00 33.82 ? 494 SER A OG 1 ATOM 2952 H H . SER A 1 188 ? 20.371 200.064 45.749 1.00 21.87 ? 494 SER A H 1 ATOM 2953 H HA . SER A 1 188 ? 18.189 201.456 46.399 1.00 28.60 ? 494 SER A HA 1 ATOM 2954 H HB2 . SER A 1 188 ? 19.605 203.301 46.585 1.00 27.97 ? 494 SER A HB2 1 ATOM 2955 H HB3 . SER A 1 188 ? 20.215 202.078 47.396 1.00 27.97 ? 494 SER A HB3 1 ATOM 2956 H HG . SER A 1 188 ? 21.537 201.745 45.683 1.00 40.59 ? 494 SER A HG 1 ATOM 2957 N N . CYS A 1 189 ? 17.589 202.678 44.428 1.00 22.68 ? 495 CYS A N 1 ATOM 2958 C CA . CYS A 1 189 ? 17.142 203.355 43.227 1.00 23.52 ? 495 CYS A CA 1 ATOM 2959 C C . CYS A 1 189 ? 17.622 204.799 43.234 1.00 23.23 ? 495 CYS A C 1 ATOM 2960 O O . CYS A 1 189 ? 17.867 205.363 44.299 1.00 27.03 ? 495 CYS A O 1 ATOM 2961 C CB . CYS A 1 189 ? 15.628 203.308 43.142 1.00 19.93 ? 495 CYS A CB 1 ATOM 2962 S SG . CYS A 1 189 ? 15.052 201.643 42.676 1.00 22.30 ? 495 CYS A SG 1 ATOM 2963 H H . CYS A 1 189 ? 17.061 202.791 45.097 1.00 27.22 ? 495 CYS A H 1 ATOM 2964 H HA . CYS A 1 189 ? 17.509 202.911 42.447 1.00 28.22 ? 495 CYS A HA 1 ATOM 2965 H HB2 . CYS A 1 189 ? 15.250 203.531 44.007 1.00 23.91 ? 495 CYS A HB2 1 ATOM 2966 H HB3 . CYS A 1 189 ? 15.323 203.936 42.468 1.00 23.91 ? 495 CYS A HB3 1 ATOM 2967 N N . PRO A 1 190 ? 17.796 205.431 42.074 1.00 22.98 ? 496 PRO A N 1 ATOM 2968 C CA . PRO A 1 190 ? 18.229 206.835 42.073 1.00 24.75 ? 496 PRO A CA 1 ATOM 2969 C C . PRO A 1 190 ? 17.214 207.738 42.760 1.00 25.23 ? 496 PRO A C 1 ATOM 2970 O O . PRO A 1 190 ? 16.002 207.497 42.719 1.00 17.27 ? 496 PRO A O 1 ATOM 2971 C CB . PRO A 1 190 ? 18.355 207.168 40.580 1.00 30.10 ? 496 PRO A CB 1 ATOM 2972 C CG . PRO A 1 190 ? 18.517 205.831 39.907 1.00 26.20 ? 496 PRO A CG 1 ATOM 2973 C CD . PRO A 1 190 ? 17.649 204.911 40.706 1.00 23.06 ? 496 PRO A CD 1 ATOM 2974 H HA . PRO A 1 190 ? 19.094 206.928 42.502 1.00 29.70 ? 496 PRO A HA 1 ATOM 2975 H HB2 . PRO A 1 190 ? 17.550 207.613 40.274 1.00 36.12 ? 496 PRO A HB2 1 ATOM 2976 H HB3 . PRO A 1 190 ? 19.135 207.726 40.432 1.00 36.12 ? 496 PRO A HB3 1 ATOM 2977 H HG2 . PRO A 1 190 ? 18.211 205.885 38.988 1.00 31.44 ? 496 PRO A HG2 1 ATOM 2978 H HG3 . PRO A 1 190 ? 19.446 205.552 39.947 1.00 31.44 ? 496 PRO A HG3 1 ATOM 2979 H HD2 . PRO A 1 190 ? 16.726 204.976 40.414 1.00 27.67 ? 496 PRO A HD2 1 ATOM 2980 H HD3 . PRO A 1 190 ? 17.978 204.000 40.651 1.00 27.67 ? 496 PRO A HD3 1 ATOM 2981 N N . ILE A 1 191 ? 17.729 208.798 43.394 1.00 30.11 ? 497 ILE A N 1 ATOM 2982 C CA . ILE A 1 191 ? 16.862 209.778 44.040 1.00 22.50 ? 497 ILE A CA 1 ATOM 2983 C C . ILE A 1 191 ? 15.902 210.340 43.006 1.00 21.95 ? 497 ILE A C 1 ATOM 2984 O O . ILE A 1 191 ? 16.302 210.713 41.897 1.00 26.28 ? 497 ILE A O 1 ATOM 2985 C CB . ILE A 1 191 ? 17.679 210.915 44.677 1.00 43.10 ? 497 ILE A CB 1 ATOM 2986 C CG1 . ILE A 1 191 ? 18.843 210.407 45.541 1.00 43.53 ? 497 ILE A CG1 1 ATOM 2987 C CG2 . ILE A 1 191 ? 16.760 211.805 45.512 1.00 37.91 ? 497 ILE A CG2 1 ATOM 2988 C CD1 . ILE A 1 191 ? 18.456 209.905 46.904 1.00 49.76 ? 497 ILE A CD1 1 ATOM 2989 H H . ILE A 1 191 ? 18.570 208.968 43.462 1.00 36.14 ? 497 ILE A H 1 ATOM 2990 H HA . ILE A 1 191 ? 16.345 209.343 44.736 1.00 27.00 ? 497 ILE A HA 1 ATOM 2991 H HB . ILE A 1 191 ? 18.050 211.454 43.962 1.00 51.72 ? 497 ILE A HB 1 ATOM 2992 H HG12 . ILE A 1 191 ? 19.277 209.676 45.073 1.00 52.23 ? 497 ILE A HG12 1 ATOM 2993 H HG13 . ILE A 1 191 ? 19.474 211.133 45.665 1.00 52.23 ? 497 ILE A HG13 1 ATOM 2994 H HG21 . ILE A 1 191 ? 17.285 212.518 45.908 1.00 45.49 ? 497 ILE A HG21 1 ATOM 2995 H HG22 . ILE A 1 191 ? 16.075 212.179 44.935 1.00 45.49 ? 497 ILE A HG22 1 ATOM 2996 H HG23 . ILE A 1 191 ? 16.349 211.269 46.208 1.00 45.49 ? 497 ILE A HG23 1 ATOM 2997 H HD11 . ILE A 1 191 ? 19.255 209.608 47.369 1.00 59.71 ? 497 ILE A HD11 1 ATOM 2998 H HD12 . ILE A 1 191 ? 18.035 210.626 47.398 1.00 59.71 ? 497 ILE A HD12 1 ATOM 2999 H HD13 . ILE A 1 191 ? 17.837 209.165 46.804 1.00 59.71 ? 497 ILE A HD13 1 ATOM 3000 N N . GLY A 1 192 ? 14.630 210.422 43.368 1.00 24.86 ? 498 GLY A N 1 ATOM 3001 C CA . GLY A 1 192 ? 13.615 210.858 42.438 1.00 21.70 ? 498 GLY A CA 1 ATOM 3002 C C . GLY A 1 192 ? 12.963 209.751 41.627 1.00 24.68 ? 498 GLY A C 1 ATOM 3003 O O . GLY A 1 192 ? 12.177 210.061 40.722 1.00 28.59 ? 498 GLY A O 1 ATOM 3004 H H . GLY A 1 192 ? 14.333 210.230 44.152 1.00 29.84 ? 498 GLY A H 1 ATOM 3005 H HA2 . GLY A 1 192 ? 12.917 211.319 42.929 1.00 26.04 ? 498 GLY A HA2 1 ATOM 3006 H HA3 . GLY A 1 192 ? 14.010 211.489 41.816 1.00 26.04 ? 498 GLY A HA3 1 ATOM 3007 N N . THR A 1 193 ? 13.268 208.478 41.908 1.00 20.89 ? 499 THR A N 1 ATOM 3008 C CA . THR A 1 193 ? 12.607 207.349 41.265 1.00 25.75 ? 499 THR A CA 1 ATOM 3009 C C . THR A 1 193 ? 11.919 206.489 42.311 1.00 25.77 ? 499 THR A C 1 ATOM 3010 O O . THR A 1 193 ? 12.313 206.463 43.479 1.00 24.04 ? 499 THR A O 1 ATOM 3011 C CB . THR A 1 193 ? 13.589 206.460 40.455 1.00 25.04 ? 499 THR A CB 1 ATOM 3012 O OG1 . THR A 1 193 ? 14.484 205.781 41.344 1.00 18.27 ? 499 THR A OG1 1 ATOM 3013 C CG2 . THR A 1 193 ? 14.396 207.292 39.432 1.00 21.55 ? 499 THR A CG2 1 ATOM 3014 H H . THR A 1 193 ? 13.867 208.244 42.479 1.00 25.07 ? 499 THR A H 1 ATOM 3015 H HA . THR A 1 193 ? 11.930 207.683 40.656 1.00 30.90 ? 499 THR A HA 1 ATOM 3016 H HB . THR A 1 193 ? 13.077 205.800 39.962 1.00 30.05 ? 499 THR A HB 1 ATOM 3017 H HG1 . THR A 1 193 ? 14.927 206.341 41.789 1.00 21.93 ? 499 THR A HG1 1 ATOM 3018 H HG21 . THR A 1 193 ? 15.001 206.715 38.940 1.00 25.86 ? 499 THR A HG21 1 ATOM 3019 H HG22 . THR A 1 193 ? 13.793 207.724 38.807 1.00 25.86 ? 499 THR A HG22 1 ATOM 3020 H HG23 . THR A 1 193 ? 14.913 207.971 39.892 1.00 25.86 ? 499 THR A HG23 1 ATOM 3021 N N . ASN A 1 194 ? 10.880 205.784 41.875 1.00 28.02 ? 500 ASN A N 1 ATOM 3022 C CA . ASN A 1 194 ? 10.144 204.885 42.746 1.00 21.06 ? 500 ASN A CA 1 ATOM 3023 C C . ASN A 1 194 ? 10.690 203.472 42.623 1.00 25.17 ? 500 ASN A C 1 ATOM 3024 O O . ASN A 1 194 ? 10.938 202.981 41.513 1.00 17.41 ? 500 ASN A O 1 ATOM 3025 C CB . ASN A 1 194 ? 8.660 204.879 42.397 1.00 22.80 ? 500 ASN A CB 1 ATOM 3026 C CG . ASN A 1 194 ? 8.080 206.267 42.311 1.00 29.69 ? 500 ASN A CG 1 ATOM 3027 O OD1 . ASN A 1 194 ? 7.404 206.606 41.349 1.00 35.12 ? 500 ASN A OD1 1 ATOM 3028 N ND2 . ASN A 1 194 ? 8.354 207.082 43.314 1.00 31.87 ? 500 ASN A ND2 1 ATOM 3029 H H . ASN A 1 194 ? 10.581 205.812 41.069 1.00 33.62 ? 500 ASN A H 1 ATOM 3030 H HA . ASN A 1 194 ? 10.242 205.174 43.666 1.00 25.28 ? 500 ASN A HA 1 ATOM 3031 H HB2 . ASN A 1 194 ? 8.539 204.449 41.536 1.00 27.36 ? 500 ASN A HB2 1 ATOM 3032 H HB3 . ASN A 1 194 ? 8.175 204.393 43.082 1.00 27.36 ? 500 ASN A HB3 1 ATOM 3033 H HD21 . ASN A 1 194 ? 8.046 207.885 43.311 1.00 38.24 ? 500 ASN A HD21 1 ATOM 3034 H HD22 . ASN A 1 194 ? 8.840 206.810 43.969 1.00 38.24 ? 500 ASN A HD22 1 ATOM 3035 N N . TYR A 1 195 ? 10.877 202.831 43.776 1.00 16.59 ? 501 TYR A N 1 ATOM 3036 C CA . TYR A 1 195 ? 11.214 201.419 43.806 1.00 20.03 ? 501 TYR A CA 1 ATOM 3037 C C . TYR A 1 195 ? 10.154 200.602 43.085 1.00 16.27 ? 501 TYR A C 1 ATOM 3038 O O . TYR A 1 195 ? 8.981 200.975 43.006 1.00 20.15 ? 501 TYR A O 1 ATOM 3039 C CB . TYR A 1 195 ? 11.383 200.935 45.258 1.00 20.44 ? 501 TYR A CB 1 ATOM 3040 C CG . TYR A 1 195 ? 12.681 201.439 45.825 1.00 16.13 ? 501 TYR A CG 1 ATOM 3041 C CD1 . TYR A 1 195 ? 13.866 200.791 45.534 1.00 16.36 ? 501 TYR A CD1 1 ATOM 3042 C CD2 . TYR A 1 195 ? 12.733 202.598 46.584 1.00 19.26 ? 501 TYR A CD2 1 ATOM 3043 C CE1 . TYR A 1 195 ? 15.060 201.261 45.986 1.00 15.83 ? 501 TYR A CE1 1 ATOM 3044 C CE2 . TYR A 1 195 ? 13.930 203.084 47.041 1.00 16.95 ? 501 TYR A CE2 1 ATOM 3045 C CZ . TYR A 1 195 ? 15.090 202.411 46.741 1.00 16.23 ? 501 TYR A CZ 1 ATOM 3046 O OH . TYR A 1 195 ? 16.293 202.882 47.206 1.00 21.79 ? 501 TYR A OH 1 ATOM 3047 H H . TYR A 1 195 ? 10.813 203.195 44.552 1.00 19.90 ? 501 TYR A H 1 ATOM 3048 H HA . TYR A 1 195 ? 12.058 201.286 43.346 1.00 24.03 ? 501 TYR A HA 1 ATOM 3049 H HB2 . TYR A 1 195 ? 10.656 201.279 45.801 1.00 24.52 ? 501 TYR A HB2 1 ATOM 3050 H HB3 . TYR A 1 195 ? 11.394 199.966 45.278 1.00 24.52 ? 501 TYR A HB3 1 ATOM 3051 H HD1 . TYR A 1 195 ? 13.847 200.022 45.011 1.00 19.63 ? 501 TYR A HD1 1 ATOM 3052 H HD2 . TYR A 1 195 ? 11.948 203.059 46.774 1.00 23.11 ? 501 TYR A HD2 1 ATOM 3053 H HE1 . TYR A 1 195 ? 15.848 200.809 45.787 1.00 19.00 ? 501 TYR A HE1 1 ATOM 3054 H HE2 . TYR A 1 195 ? 13.956 203.857 47.558 1.00 20.34 ? 501 TYR A HE2 1 ATOM 3055 H HH . TYR A 1 195 ? 16.175 203.585 47.650 1.00 26.15 ? 501 TYR A HH 1 ATOM 3056 N N . ARG A 1 196 ? 10.604 199.506 42.507 1.00 16.64 ? 502 ARG A N 1 ATOM 3057 C CA . ARG A 1 196 ? 9.706 198.498 41.971 1.00 19.06 ? 502 ARG A CA 1 ATOM 3058 C C . ARG A 1 196 ? 8.570 198.206 42.941 1.00 24.26 ? 502 ARG A C 1 ATOM 3059 O O . ARG A 1 196 ? 8.782 198.041 44.147 1.00 27.04 ? 502 ARG A O 1 ATOM 3060 C CB . ARG A 1 196 ? 10.513 197.236 41.697 1.00 23.20 ? 502 ARG A CB 1 ATOM 3061 C CG . ARG A 1 196 ? 9.755 196.107 41.075 1.00 24.96 ? 502 ARG A CG 1 ATOM 3062 C CD . ARG A 1 196 ? 10.709 194.972 40.759 1.00 18.04 ? 502 ARG A CD 1 ATOM 3063 N NE . ARG A 1 196 ? 10.002 193.859 40.152 1.00 23.61 ? 502 ARG A NE 1 ATOM 3064 C CZ . ARG A 1 196 ? 10.397 192.593 40.203 1.00 17.69 ? 502 ARG A CZ 1 ATOM 3065 N NH1 . ARG A 1 196 ? 11.497 192.259 40.860 1.00 19.97 ? 502 ARG A NH1 1 ATOM 3066 N NH2 . ARG A 1 196 ? 9.686 191.668 39.587 1.00 17.92 ? 502 ARG A NH2 1 ATOM 3067 H H . ARG A 1 196 ? 11.437 199.318 42.409 1.00 19.96 ? 502 ARG A H 1 ATOM 3068 H HA . ARG A 1 196 ? 9.326 198.810 41.135 1.00 22.87 ? 502 ARG A HA 1 ATOM 3069 H HB2 . ARG A 1 196 ? 11.241 197.463 41.097 1.00 27.84 ? 502 ARG A HB2 1 ATOM 3070 H HB3 . ARG A 1 196 ? 10.875 196.915 42.538 1.00 27.84 ? 502 ARG A HB3 1 ATOM 3071 H HG2 . ARG A 1 196 ? 9.084 195.783 41.696 1.00 29.95 ? 502 ARG A HG2 1 ATOM 3072 H HG3 . ARG A 1 196 ? 9.343 196.405 40.249 1.00 29.95 ? 502 ARG A HG3 1 ATOM 3073 H HD2 . ARG A 1 196 ? 11.384 195.283 40.135 1.00 21.65 ? 502 ARG A HD2 1 ATOM 3074 H HD3 . ARG A 1 196 ? 11.124 194.661 41.579 1.00 21.65 ? 502 ARG A HD3 1 ATOM 3075 H HE . ARG A 1 196 ? 9.274 194.032 39.728 1.00 28.33 ? 502 ARG A HE 1 ATOM 3076 H HH11 . ARG A 1 196 ? 11.963 192.865 41.254 1.00 23.96 ? 502 ARG A HH11 1 ATOM 3077 H HH12 . ARG A 1 196 ? 11.746 191.437 40.892 1.00 23.96 ? 502 ARG A HH12 1 ATOM 3078 H HH21 . ARG A 1 196 ? 8.969 191.886 39.166 1.00 21.50 ? 502 ARG A HH21 1 ATOM 3079 H HH22 . ARG A 1 196 ? 9.929 190.843 39.625 1.00 21.50 ? 502 ARG A HH22 1 ATOM 3080 N N . SER A 1 197 ? 7.363 198.119 42.399 1.00 19.89 ? 503 SER A N 1 ATOM 3081 C CA . SER A 1 197 ? 6.180 197.839 43.199 1.00 25.72 ? 503 SER A CA 1 ATOM 3082 C C . SER A 1 197 ? 6.153 196.359 43.597 1.00 32.96 ? 503 SER A C 1 ATOM 3083 O O . SER A 1 197 ? 6.181 195.465 42.736 1.00 22.13 ? 503 SER A O 1 ATOM 3084 C CB . SER A 1 197 ? 4.932 198.221 42.412 1.00 28.55 ? 503 SER A CB 1 ATOM 3085 O OG . SER A 1 197 ? 3.761 198.044 43.183 1.00 43.76 ? 503 SER A OG 1 ATOM 3086 H H . SER A 1 197 ? 7.201 198.220 41.561 1.00 23.87 ? 503 SER A H 1 ATOM 3087 H HA . SER A 1 197 ? 6.206 198.373 44.009 1.00 30.86 ? 503 SER A HA 1 ATOM 3088 H HB2 . SER A 1 197 ? 4.998 199.153 42.151 1.00 34.26 ? 503 SER A HB2 1 ATOM 3089 H HB3 . SER A 1 197 ? 4.875 197.661 41.622 1.00 34.26 ? 503 SER A HB3 1 ATOM 3090 H HG . SER A 1 197 ? 3.086 198.259 42.732 1.00 52.51 ? 503 SER A HG 1 ATOM 3091 N N . CYS A 1 198 ? 6.091 196.105 44.903 1.00 26.24 ? 504 CYS A N 1 ATOM 3092 C CA . CYS A 1 198 ? 6.192 194.761 45.451 1.00 29.39 ? 504 CYS A CA 1 ATOM 3093 C C . CYS A 1 198 ? 5.222 194.587 46.614 1.00 32.06 ? 504 CYS A C 1 ATOM 3094 O O . CYS A 1 198 ? 4.928 195.536 47.348 1.00 29.59 ? 504 CYS A O 1 ATOM 3095 C CB . CYS A 1 198 ? 7.602 194.464 45.961 1.00 29.44 ? 504 CYS A CB 1 ATOM 3096 S SG . CYS A 1 198 ? 8.892 194.382 44.744 1.00 22.71 ? 504 CYS A SG 1 ATOM 3097 H H . CYS A 1 198 ? 5.988 196.713 45.503 1.00 31.49 ? 504 CYS A H 1 ATOM 3098 H HA . CYS A 1 198 ? 5.969 194.113 44.764 1.00 35.26 ? 504 CYS A HA 1 ATOM 3099 H HB2 . CYS A 1 198 ? 7.847 195.158 46.593 1.00 35.33 ? 504 CYS A HB2 1 ATOM 3100 H HB3 . CYS A 1 198 ? 7.584 193.608 46.418 1.00 35.33 ? 504 CYS A HB3 1 ATOM 3101 N N . GLU A 1 199 ? 4.760 193.351 46.801 1.00 24.82 ? 505 GLU A N 1 ATOM 3102 C CA . GLU A 1 199 ? 3.812 193.021 47.850 1.00 32.17 ? 505 GLU A CA 1 ATOM 3103 C C . GLU A 1 199 ? 4.213 191.708 48.509 1.00 31.56 ? 505 GLU A C 1 ATOM 3104 O O . GLU A 1 199 ? 4.658 190.770 47.842 1.00 26.82 ? 505 GLU A O 1 ATOM 3105 C CB . GLU A 1 199 ? 2.385 192.924 47.292 1.00 37.05 ? 505 GLU A CB 1 ATOM 3106 C CG . GLU A 1 199 ? 1.857 194.232 46.677 1.00 60.12 ? 505 GLU A CG 1 ATOM 3107 C CD . GLU A 1 199 ? 0.767 194.006 45.624 1.00 86.80 ? 505 GLU A CD 1 ATOM 3108 O OE1 . GLU A 1 199 ? 0.694 192.883 45.058 1.00 77.82 ? 505 GLU A OE1 1 ATOM 3109 O OE2 . GLU A 1 199 ? -0.010 194.956 45.360 1.00 84.29 ? 505 GLU A OE2 1 ATOM 3110 H H . GLU A 1 199 ? 4.989 192.676 46.319 1.00 29.79 ? 505 GLU A H 1 ATOM 3111 H HA . GLU A 1 199 ? 3.828 193.718 48.525 1.00 38.61 ? 505 GLU A HA 1 ATOM 3112 H HB2 . GLU A 1 199 ? 2.368 192.245 46.600 1.00 44.46 ? 505 GLU A HB2 1 ATOM 3113 H HB3 . GLU A 1 199 ? 1.786 192.673 48.012 1.00 44.46 ? 505 GLU A HB3 1 ATOM 3114 H HG2 . GLU A 1 199 ? 1.481 194.782 47.382 1.00 72.14 ? 505 GLU A HG2 1 ATOM 3115 H HG3 . GLU A 1 199 ? 2.592 194.699 46.250 1.00 72.14 ? 505 GLU A HG3 1 ATOM 3116 N N . SER A 1 200 ? 4.068 191.655 49.826 1.00 36.64 ? 506 SER A N 1 ATOM 3117 C CA . SER A 1 200 ? 4.273 190.438 50.591 1.00 31.47 ? 506 SER A CA 1 ATOM 3118 C C . SER A 1 200 ? 2.921 189.962 51.091 1.00 33.16 ? 506 SER A C 1 ATOM 3119 O O . SER A 1 200 ? 2.101 190.770 51.538 1.00 36.14 ? 506 SER A O 1 ATOM 3120 C CB . SER A 1 200 ? 5.227 190.672 51.757 1.00 32.97 ? 506 SER A CB 1 ATOM 3121 O OG . SER A 1 200 ? 5.578 189.441 52.367 1.00 33.65 ? 506 SER A OG 1 ATOM 3122 H H . SER A 1 200 ? 3.845 192.330 50.310 1.00 43.97 ? 506 SER A H 1 ATOM 3123 H HA . SER A 1 200 ? 4.649 189.752 50.016 1.00 37.77 ? 506 SER A HA 1 ATOM 3124 H HB2 . SER A 1 200 ? 6.031 191.103 51.427 1.00 39.56 ? 506 SER A HB2 1 ATOM 3125 H HB3 . SER A 1 200 ? 4.792 191.238 52.414 1.00 39.56 ? 506 SER A HB3 1 ATOM 3126 H HG . SER A 1 200 ? 5.955 188.940 51.807 1.00 40.39 ? 506 SER A HG 1 ATOM 3127 N N . THR A 1 201 ? 2.665 188.667 50.963 1.00 35.61 ? 507 THR A N 1 ATOM 3128 C CA . THR A 1 201 ? 1.422 188.108 51.458 1.00 37.04 ? 507 THR A CA 1 ATOM 3129 C C . THR A 1 201 ? 1.669 186.743 52.057 1.00 35.70 ? 507 THR A C 1 ATOM 3130 O O . THR A 1 201 ? 2.739 186.143 51.927 1.00 31.06 ? 507 THR A O 1 ATOM 3131 C CB . THR A 1 201 ? 0.338 187.975 50.378 1.00 43.89 ? 507 THR A CB 1 ATOM 3132 O OG1 . THR A 1 201 ? 0.924 187.593 49.126 1.00 46.46 ? 507 THR A OG1 1 ATOM 3133 C CG2 . THR A 1 201 ? -0.441 189.282 50.240 1.00 61.00 ? 507 THR A CG2 1 ATOM 3134 H H . THR A 1 201 ? 3.192 188.096 50.595 1.00 42.73 ? 507 THR A H 1 ATOM 3135 H HA . THR A 1 201 ? 1.076 188.684 52.157 1.00 44.45 ? 507 THR A HA 1 ATOM 3136 H HB . THR A 1 201 ? -0.288 187.286 50.650 1.00 52.66 ? 507 THR A HB 1 ATOM 3137 H HG1 . THR A 1 201 ? 0.327 187.522 48.539 1.00 55.76 ? 507 THR A HG1 1 ATOM 3138 H HG21 . THR A 1 201 ? -1.123 189.190 49.557 1.00 73.20 ? 507 THR A HG21 1 ATOM 3139 H HG22 . THR A 1 201 ? -0.867 189.504 51.083 1.00 73.20 ? 507 THR A HG22 1 ATOM 3140 H HG23 . THR A 1 201 ? 0.160 190.001 49.991 1.00 73.20 ? 507 THR A HG23 1 ATOM 3141 N N . THR A 1 202 ? 0.650 186.293 52.754 1.00 47.92 ? 508 THR A N 1 ATOM 3142 C CA . THR A 1 202 ? 0.568 184.940 53.239 1.00 45.17 ? 508 THR A CA 1 ATOM 3143 C C . THR A 1 202 ? -0.144 184.101 52.190 1.00 54.09 ? 508 THR A C 1 ATOM 3144 O O . THR A 1 202 ? -0.992 184.590 51.430 1.00 43.03 ? 508 THR A O 1 ATOM 3145 C CB . THR A 1 202 ? -0.165 184.919 54.572 1.00 41.24 ? 508 THR A CB 1 ATOM 3146 O OG1 . THR A 1 202 ? 0.749 185.321 55.611 1.00 48.02 ? 508 THR A OG1 1 ATOM 3147 C CG2 . THR A 1 202 ? -0.755 183.538 54.866 1.00 48.39 ? 508 THR A CG2 1 ATOM 3148 H H . THR A 1 202 ? -0.031 186.773 52.967 1.00 57.50 ? 508 THR A H 1 ATOM 3149 H HA . THR A 1 202 ? 1.460 184.583 53.369 1.00 54.21 ? 508 THR A HA 1 ATOM 3150 H HB . THR A 1 202 ? -0.898 185.554 54.536 1.00 49.49 ? 508 THR A HB 1 ATOM 3151 H HG1 . THR A 1 202 ? 0.359 185.315 56.355 1.00 57.63 ? 508 THR A HG1 1 ATOM 3152 H HG21 . THR A 1 202 ? -1.216 183.549 55.719 1.00 58.07 ? 508 THR A HG21 1 ATOM 3153 H HG22 . THR A 1 202 ? -1.384 183.291 54.170 1.00 58.07 ? 508 THR A HG22 1 ATOM 3154 H HG23 . THR A 1 202 ? -0.046 182.876 54.899 1.00 58.07 ? 508 THR A HG23 1 ATOM 3155 N N . VAL A 1 203 ? 0.249 182.841 52.113 1.00 41.58 ? 509 VAL A N 1 ATOM 3156 C CA . VAL A 1 203 ? -0.452 181.924 51.233 1.00 40.64 ? 509 VAL A CA 1 ATOM 3157 C C . VAL A 1 203 ? 0.062 180.521 51.509 1.00 32.92 ? 509 VAL A C 1 ATOM 3158 O O . VAL A 1 203 ? 1.255 180.236 51.357 1.00 26.90 ? 509 VAL A O 1 ATOM 3159 C CB . VAL A 1 203 ? -0.304 182.354 49.757 1.00 42.98 ? 509 VAL A CB 1 ATOM 3160 C CG1 . VAL A 1 203 ? 1.142 182.724 49.406 1.00 36.18 ? 509 VAL A CG1 1 ATOM 3161 C CG2 . VAL A 1 203 ? -0.850 181.290 48.831 1.00 43.95 ? 509 VAL A CG2 1 ATOM 3162 H H . VAL A 1 203 ? 0.904 182.496 52.551 1.00 49.89 ? 509 VAL A H 1 ATOM 3163 H HA . VAL A 1 203 ? -1.397 181.942 51.452 1.00 48.77 ? 509 VAL A HA 1 ATOM 3164 H HB . VAL A 1 203 ? -0.841 183.150 49.622 1.00 51.57 ? 509 VAL A HB 1 ATOM 3165 H HG11 . VAL A 1 203 ? 1.182 182.985 48.473 1.00 43.41 ? 509 VAL A HG11 1 ATOM 3166 H HG12 . VAL A 1 203 ? 1.424 183.461 49.970 1.00 43.41 ? 509 VAL A HG12 1 ATOM 3167 H HG13 . VAL A 1 203 ? 1.710 181.953 49.560 1.00 43.41 ? 509 VAL A HG13 1 ATOM 3168 H HG21 . VAL A 1 203 ? -0.744 181.585 47.913 1.00 52.74 ? 509 VAL A HG21 1 ATOM 3169 H HG22 . VAL A 1 203 ? -0.358 180.466 48.972 1.00 52.74 ? 509 VAL A HG22 1 ATOM 3170 H HG23 . VAL A 1 203 ? -1.790 181.152 49.028 1.00 52.74 ? 509 VAL A HG23 1 ATOM 3171 N N . LEU A 1 204 ? -0.836 179.671 52.003 1.00 35.87 ? 510 LEU A N 1 ATOM 3172 C CA . LEU A 1 204 ? -0.608 178.244 52.176 1.00 35.32 ? 510 LEU A CA 1 ATOM 3173 C C . LEU A 1 204 ? 0.774 177.902 52.725 1.00 28.76 ? 510 LEU A C 1 ATOM 3174 O O . LEU A 1 204 ? 1.567 177.229 52.056 1.00 42.67 ? 510 LEU A O 1 ATOM 3175 C CB . LEU A 1 204 ? -0.813 177.530 50.839 1.00 37.91 ? 510 LEU A CB 1 ATOM 3176 C CG . LEU A 1 204 ? -1.987 178.004 49.992 1.00 38.89 ? 510 LEU A CG 1 ATOM 3177 C CD1 . LEU A 1 204 ? -1.595 177.961 48.521 1.00 41.29 ? 510 LEU A CD1 1 ATOM 3178 C CD2 . LEU A 1 204 ? -3.191 177.125 50.256 1.00 32.16 ? 510 LEU A CD2 1 ATOM 3179 H H . LEU A 1 204 ? -1.622 179.915 52.255 1.00 43.05 ? 510 LEU A H 1 ATOM 3180 H HA . LEU A 1 204 ? -1.265 177.898 52.800 1.00 42.38 ? 510 LEU A HA 1 ATOM 3181 H HB2 . LEU A 1 204 ? -0.010 177.645 50.307 1.00 45.49 ? 510 LEU A HB2 1 ATOM 3182 H HB3 . LEU A 1 204 ? -0.949 176.586 51.016 1.00 45.49 ? 510 LEU A HB3 1 ATOM 3183 H HG . LEU A 1 204 ? -2.212 178.918 50.227 1.00 46.67 ? 510 LEU A HG 1 ATOM 3184 H HD11 . LEU A 1 204 ? -2.346 178.263 47.985 1.00 49.55 ? 510 LEU A HD11 1 ATOM 3185 H HD12 . LEU A 1 204 ? -0.832 178.543 48.380 1.00 49.55 ? 510 LEU A HD12 1 ATOM 3186 H HD13 . LEU A 1 204 ? -1.364 177.049 48.282 1.00 49.55 ? 510 LEU A HD13 1 ATOM 3187 H HD21 . LEU A 1 204 ? -3.933 177.435 49.712 1.00 38.59 ? 510 LEU A HD21 1 ATOM 3188 H HD22 . LEU A 1 204 ? -2.970 176.210 50.024 1.00 38.59 ? 510 LEU A HD22 1 ATOM 3189 H HD23 . LEU A 1 204 ? -3.423 177.182 51.196 1.00 38.59 ? 510 LEU A HD23 1 ATOM 3190 N N . ASP A 1 205 ? 1.073 178.355 53.929 1.00 25.36 ? 511 ASP A N 1 ATOM 3191 C CA . ASP A 1 205 ? 2.279 178.008 54.667 1.00 30.26 ? 511 ASP A CA 1 ATOM 3192 C C . ASP A 1 205 ? 3.484 178.764 54.155 1.00 27.24 ? 511 ASP A C 1 ATOM 3193 O O . ASP A 1 205 ? 4.591 178.542 54.659 1.00 36.88 ? 511 ASP A O 1 ATOM 3194 C CB . ASP A 1 205 ? 2.563 176.499 54.644 1.00 32.00 ? 511 ASP A CB 1 ATOM 3195 C CG . ASP A 1 205 ? 1.456 175.716 55.307 1.00 37.14 ? 511 ASP A CG 1 ATOM 3196 O OD1 . ASP A 1 205 ? 0.659 176.355 56.037 1.00 38.30 ? 511 ASP A OD1 1 ATOM 3197 O OD2 . ASP A 1 205 ? 1.377 174.488 55.113 1.00 33.32 ? 511 ASP A OD2 1 ATOM 3198 H H . ASP A 1 205 ? 0.564 178.895 54.363 1.00 30.43 ? 511 ASP A H 1 ATOM 3199 H HA . ASP A 1 205 ? 2.151 178.263 55.594 1.00 36.32 ? 511 ASP A HA 1 ATOM 3200 H HB2 . ASP A 1 205 ? 2.637 176.202 53.724 1.00 38.40 ? 511 ASP A HB2 1 ATOM 3201 H HB3 . ASP A 1 205 ? 3.388 176.322 55.122 1.00 38.40 ? 511 ASP A HB3 1 ATOM 3202 N N . HIS A 1 206 ? 3.316 179.652 53.188 1.00 26.18 ? 512 HIS A N 1 ATOM 3203 C CA . HIS A 1 206 ? 4.330 180.646 52.869 1.00 26.82 ? 512 HIS A CA 1 ATOM 3204 C C . HIS A 1 206 ? 3.968 181.887 53.689 1.00 21.58 ? 512 HIS A C 1 ATOM 3205 O O . HIS A 1 206 ? 2.995 182.582 53.386 1.00 24.27 ? 512 HIS A O 1 ATOM 3206 C CB . HIS A 1 206 ? 4.365 180.895 51.361 1.00 24.79 ? 512 HIS A CB 1 ATOM 3207 C CG . HIS A 1 206 ? 4.835 179.711 50.559 1.00 21.64 ? 512 HIS A CG 1 ATOM 3208 N ND1 . HIS A 1 206 ? 6.170 179.413 50.386 1.00 17.98 ? 512 HIS A ND1 1 ATOM 3209 C CD2 . HIS A 1 206 ? 4.150 178.765 49.873 1.00 17.58 ? 512 HIS A CD2 1 ATOM 3210 C CE1 . HIS A 1 206 ? 6.289 178.331 49.640 1.00 16.02 ? 512 HIS A CE1 1 ATOM 3211 N NE2 . HIS A 1 206 ? 5.077 177.915 49.319 1.00 19.47 ? 512 HIS A NE2 1 ATOM 3212 H H . HIS A 1 206 ? 2.613 179.701 52.694 1.00 31.41 ? 512 HIS A H 1 ATOM 3213 H HA . HIS A 1 206 ? 5.201 180.328 53.152 1.00 32.19 ? 512 HIS A HA 1 ATOM 3214 H HB2 . HIS A 1 206 ? 3.470 181.120 51.061 1.00 29.74 ? 512 HIS A HB2 1 ATOM 3215 H HB3 . HIS A 1 206 ? 4.967 181.634 51.181 1.00 29.74 ? 512 HIS A HB3 1 ATOM 3216 H HD2 . HIS A 1 206 ? 3.226 178.697 49.801 1.00 21.09 ? 512 HIS A HD2 1 ATOM 3217 H HE1 . HIS A 1 206 ? 7.088 177.929 49.386 1.00 19.23 ? 512 HIS A HE1 1 ATOM 3218 H HE2 . HIS A 1 206 ? 4.897 177.228 48.833 1.00 23.36 ? 512 HIS A HE2 1 ATOM 3219 N N . THR A 1 207 ? 4.717 182.142 54.770 1.00 23.92 ? 513 THR A N 1 ATOM 3220 C CA . THR A 1 207 ? 4.364 183.272 55.632 1.00 34.03 ? 513 THR A CA 1 ATOM 3221 C C . THR A 1 207 ? 4.695 184.602 54.965 1.00 33.38 ? 513 THR A C 1 ATOM 3222 O O . THR A 1 207 ? 4.028 185.612 55.230 1.00 29.48 ? 513 THR A O 1 ATOM 3223 C CB . THR A 1 207 ? 5.081 183.199 56.986 1.00 28.65 ? 513 THR A CB 1 ATOM 3224 O OG1 . THR A 1 207 ? 6.502 183.300 56.804 1.00 29.63 ? 513 THR A OG1 1 ATOM 3225 C CG2 . THR A 1 207 ? 4.760 181.905 57.731 1.00 26.62 ? 513 THR A CG2 1 ATOM 3226 H H . THR A 1 207 ? 5.408 181.693 55.018 1.00 28.71 ? 513 THR A H 1 ATOM 3227 H HA . THR A 1 207 ? 3.409 183.253 55.800 1.00 40.83 ? 513 THR A HA 1 ATOM 3228 H HB . THR A 1 207 ? 4.784 183.940 57.538 1.00 34.38 ? 513 THR A HB 1 ATOM 3229 H HG1 . THR A 1 207 ? 6.693 184.030 56.436 1.00 35.55 ? 513 THR A HG1 1 ATOM 3230 H HG21 . THR A 1 207 ? 5.226 181.888 58.582 1.00 31.95 ? 513 THR A HG21 1 ATOM 3231 H HG22 . THR A 1 207 ? 3.806 181.845 57.894 1.00 31.95 ? 513 THR A HG22 1 ATOM 3232 H HG23 . THR A 1 207 ? 5.039 181.141 57.203 1.00 31.95 ? 513 THR A HG23 1 ATOM 3233 N N . ASP A 1 208 ? 5.707 184.613 54.094 1.00 27.08 ? 514 ASP A N 1 ATOM 3234 C CA . ASP A 1 208 ? 6.244 185.836 53.517 1.00 24.28 ? 514 ASP A CA 1 ATOM 3235 C C . ASP A 1 208 ? 6.453 185.656 52.015 1.00 20.79 ? 514 ASP A C 1 ATOM 3236 O O . ASP A 1 208 ? 7.562 185.660 51.496 1.00 19.82 ? 514 ASP A O 1 ATOM 3237 C CB . ASP A 1 208 ? 7.532 186.200 54.246 1.00 27.92 ? 514 ASP A CB 1 ATOM 3238 C CG . ASP A 1 208 ? 7.273 186.635 55.682 1.00 27.53 ? 514 ASP A CG 1 ATOM 3239 O OD1 . ASP A 1 208 ? 6.796 187.769 55.877 1.00 30.72 ? 514 ASP A OD1 1 ATOM 3240 O OD2 . ASP A 1 208 ? 7.533 185.851 56.606 1.00 29.77 ? 514 ASP A OD2 1 ATOM 3241 H H . ASP A 1 208 ? 6.105 183.903 53.819 1.00 32.49 ? 514 ASP A H 1 ATOM 3242 H HA . ASP A 1 208 ? 5.609 186.557 53.649 1.00 29.14 ? 514 ASP A HA 1 ATOM 3243 H HB2 . ASP A 1 208 ? 8.116 185.426 54.266 1.00 33.51 ? 514 ASP A HB2 1 ATOM 3244 H HB3 . ASP A 1 208 ? 7.965 186.933 53.781 1.00 33.51 ? 514 ASP A HB3 1 ATOM 3245 N N . TRP A 1 209 ? 5.356 185.481 51.297 1.00 23.56 ? 515 TRP A N 1 ATOM 3246 C CA . TRP A 1 209 ? 5.411 185.243 49.857 1.00 29.25 ? 515 TRP A CA 1 ATOM 3247 C C . TRP A 1 209 ? 5.482 186.595 49.148 1.00 25.90 ? 515 TRP A C 1 ATOM 3248 O O . TRP A 1 209 ? 4.532 187.379 49.194 1.00 23.16 ? 515 TRP A O 1 ATOM 3249 C CB . TRP A 1 209 ? 4.199 184.425 49.412 1.00 23.49 ? 515 TRP A CB 1 ATOM 3250 C CG . TRP A 1 209 ? 4.130 184.129 47.957 1.00 22.16 ? 515 TRP A CG 1 ATOM 3251 C CD1 . TRP A 1 209 ? 3.713 184.973 46.970 1.00 27.15 ? 515 TRP A CD1 1 ATOM 3252 C CD2 . TRP A 1 209 ? 4.468 182.896 47.308 1.00 28.31 ? 515 TRP A CD2 1 ATOM 3253 N NE1 . TRP A 1 209 ? 3.775 184.349 45.746 1.00 31.44 ? 515 TRP A NE1 1 ATOM 3254 C CE2 . TRP A 1 209 ? 4.238 183.075 45.922 1.00 29.84 ? 515 TRP A CE2 1 ATOM 3255 C CE3 . TRP A 1 209 ? 4.948 181.663 47.756 1.00 21.44 ? 515 TRP A CE3 1 ATOM 3256 C CZ2 . TRP A 1 209 ? 4.462 182.069 44.992 1.00 29.28 ? 515 TRP A CZ2 1 ATOM 3257 C CZ3 . TRP A 1 209 ? 5.182 180.665 46.828 1.00 26.39 ? 515 TRP A CZ3 1 ATOM 3258 C CH2 . TRP A 1 209 ? 4.938 180.870 45.460 1.00 24.40 ? 515 TRP A CH2 1 ATOM 3259 H H . TRP A 1 209 ? 4.558 185.495 51.619 1.00 28.27 ? 515 TRP A H 1 ATOM 3260 H HA . TRP A 1 209 ? 6.213 184.742 49.643 1.00 35.10 ? 515 TRP A HA 1 ATOM 3261 H HB2 . TRP A 1 209 ? 4.211 183.576 49.882 1.00 28.19 ? 515 TRP A HB2 1 ATOM 3262 H HB3 . TRP A 1 209 ? 3.395 184.914 49.648 1.00 28.19 ? 515 TRP A HB3 1 ATOM 3263 H HD1 . TRP A 1 209 ? 3.426 185.847 47.106 1.00 32.58 ? 515 TRP A HD1 1 ATOM 3264 H HE1 . TRP A 1 209 ? 3.559 184.703 44.993 1.00 37.73 ? 515 TRP A HE1 1 ATOM 3265 H HE3 . TRP A 1 209 ? 5.112 181.518 48.660 1.00 25.73 ? 515 TRP A HE3 1 ATOM 3266 H HZ2 . TRP A 1 209 ? 4.307 182.206 44.085 1.00 35.13 ? 515 TRP A HZ2 1 ATOM 3267 H HZ3 . TRP A 1 209 ? 5.499 179.840 47.116 1.00 31.67 ? 515 TRP A HZ3 1 ATOM 3268 H HH2 . TRP A 1 209 ? 5.102 180.179 44.860 1.00 29.28 ? 515 TRP A HH2 1 ATOM 3269 N N . CYS A 1 210 ? 6.609 186.866 48.501 1.00 19.60 ? 516 CYS A N 1 ATOM 3270 C CA . CYS A 1 210 ? 6.860 188.134 47.837 1.00 25.32 ? 516 CYS A CA 1 ATOM 3271 C C . CYS A 1 210 ? 6.648 188.009 46.333 1.00 26.62 ? 516 CYS A C 1 ATOM 3272 O O . CYS A 1 210 ? 7.222 187.118 45.689 1.00 19.22 ? 516 CYS A O 1 ATOM 3273 C CB . CYS A 1 210 ? 8.278 188.606 48.150 1.00 24.78 ? 516 CYS A CB 1 ATOM 3274 S SG . CYS A 1 210 ? 8.419 189.109 49.927 1.00 25.94 ? 516 CYS A SG 1 ATOM 3275 H H . CYS A 1 210 ? 7.263 186.311 48.433 1.00 23.51 ? 516 CYS A H 1 ATOM 3276 H HA . CYS A 1 210 ? 6.240 188.798 48.175 1.00 30.39 ? 516 CYS A HA 1 ATOM 3277 H HB2 . CYS A 1 210 ? 8.904 187.884 47.985 1.00 29.74 ? 516 CYS A HB2 1 ATOM 3278 H HB3 . CYS A 1 210 ? 8.493 189.373 47.596 1.00 29.74 ? 516 CYS A HB3 1 ATOM 3279 N N . ARG A 1 211 ? 5.804 188.897 45.790 1.00 26.91 ? 517 ARG A N 1 ATOM 3280 C CA . ARG A 1 211 ? 5.589 189.054 44.357 1.00 20.95 ? 517 ARG A CA 1 ATOM 3281 C C . ARG A 1 211 ? 5.696 190.522 43.993 1.00 26.23 ? 517 ARG A C 1 ATOM 3282 O O . ARG A 1 211 ? 5.122 191.385 44.668 1.00 21.37 ? 517 ARG A O 1 ATOM 3283 C CB . ARG A 1 211 ? 4.222 188.529 43.891 1.00 27.87 ? 517 ARG A CB 1 ATOM 3284 C CG . ARG A 1 211 ? 4.120 187.012 43.541 1.00 47.45 ? 517 ARG A CG 1 ATOM 3285 C CD . ARG A 1 211 ? 5.467 186.315 43.531 1.00 32.96 ? 517 ARG A CD 1 ATOM 3286 N NE . ARG A 1 211 ? 5.602 185.255 42.570 1.00 37.59 ? 517 ARG A NE 1 ATOM 3287 C CZ . ARG A 1 211 ? 6.777 184.881 42.068 1.00 48.20 ? 517 ARG A CZ 1 ATOM 3288 N NH1 . ARG A 1 211 ? 7.897 185.511 42.434 1.00 33.72 ? 517 ARG A NH1 1 ATOM 3289 N NH2 . ARG A 1 211 ? 6.837 183.886 41.190 1.00 50.27 ? 517 ARG A NH2 1 ATOM 3290 H H . ARG A 1 211 ? 5.327 189.438 46.259 1.00 32.29 ? 517 ARG A H 1 ATOM 3291 H HA . ARG A 1 211 ? 6.280 188.571 43.877 1.00 25.14 ? 517 ARG A HA 1 ATOM 3292 H HB2 . ARG A 1 211 ? 3.578 188.703 44.594 1.00 33.45 ? 517 ARG A HB2 1 ATOM 3293 H HB3 . ARG A 1 211 ? 3.967 189.022 43.095 1.00 33.45 ? 517 ARG A HB3 1 ATOM 3294 H HG2 . ARG A 1 211 ? 3.561 186.573 44.201 1.00 56.94 ? 517 ARG A HG2 1 ATOM 3295 H HG3 . ARG A 1 211 ? 3.728 186.917 42.659 1.00 56.94 ? 517 ARG A HG3 1 ATOM 3296 H HD2 . ARG A 1 211 ? 6.152 186.973 43.338 1.00 39.55 ? 517 ARG A HD2 1 ATOM 3297 H HD3 . ARG A 1 211 ? 5.622 185.934 44.409 1.00 39.55 ? 517 ARG A HD3 1 ATOM 3298 H HE . ARG A 1 211 ? 4.927 184.737 42.445 1.00 45.11 ? 517 ARG A HE 1 ATOM 3299 H HH11 . ARG A 1 211 ? 7.862 186.154 43.004 1.00 40.46 ? 517 ARG A HH11 1 ATOM 3300 H HH12 . ARG A 1 211 ? 8.654 185.268 42.106 1.00 40.46 ? 517 ARG A HH12 1 ATOM 3301 H HH21 . ARG A 1 211 ? 6.117 183.481 40.948 1.00 60.32 ? 517 ARG A HH21 1 ATOM 3302 H HH22 . ARG A 1 211 ? 7.595 183.648 40.860 1.00 60.32 ? 517 ARG A HH22 1 ATOM 3303 N N . CYS A 1 212 ? 6.430 190.794 42.934 1.00 16.71 ? 518 CYS A N 1 ATOM 3304 C CA . CYS A 1 212 ? 6.606 192.136 42.435 1.00 22.67 ? 518 CYS A CA 1 ATOM 3305 C C . CYS A 1 212 ? 5.987 192.254 41.046 1.00 20.88 ? 518 CYS A C 1 ATOM 3306 O O . CYS A 1 212 ? 5.408 191.308 40.503 1.00 20.04 ? 518 CYS A O 1 ATOM 3307 C CB . CYS A 1 212 ? 8.091 192.506 42.431 1.00 22.98 ? 518 CYS A CB 1 ATOM 3308 S SG . CYS A 1 212 ? 8.871 192.443 44.060 1.00 22.07 ? 518 CYS A SG 1 ATOM 3309 H H . CYS A 1 212 ? 6.847 190.199 42.474 1.00 20.06 ? 518 CYS A H 1 ATOM 3310 H HA . CYS A 1 212 ? 6.145 192.755 43.022 1.00 27.20 ? 518 CYS A HA 1 ATOM 3311 H HB2 . CYS A 1 212 ? 8.564 191.888 41.853 1.00 27.58 ? 518 CYS A HB2 1 ATOM 3312 H HB3 . CYS A 1 212 ? 8.186 193.410 42.092 1.00 27.58 ? 518 CYS A HB3 1 ATOM 3313 N N . SER A 1 213 ? 6.124 193.444 40.475 1.00 22.10 ? 519 SER A N 1 ATOM 3314 C CA . SER A 1 213 ? 5.497 193.790 39.213 1.00 21.44 ? 519 SER A CA 1 ATOM 3315 C C . SER A 1 213 ? 6.214 193.152 38.027 1.00 20.54 ? 519 SER A C 1 ATOM 3316 O O . SER A 1 213 ? 7.389 192.790 38.097 1.00 20.09 ? 519 SER A O 1 ATOM 3317 C CB . SER A 1 213 ? 5.532 195.300 39.029 1.00 21.06 ? 519 SER A CB 1 ATOM 3318 O OG . SER A 1 213 ? 6.885 195.712 39.071 1.00 21.74 ? 519 SER A OG 1 ATOM 3319 H H . SER A 1 213 ? 6.589 194.084 40.812 1.00 26.52 ? 519 SER A H 1 ATOM 3320 H HA . SER A 1 213 ? 4.573 193.497 39.214 1.00 25.73 ? 519 SER A HA 1 ATOM 3321 H HB2 . SER A 1 213 ? 5.148 195.532 38.169 1.00 25.27 ? 519 SER A HB2 1 ATOM 3322 H HB3 . SER A 1 213 ? 5.040 195.726 39.749 1.00 25.27 ? 519 SER A HB3 1 ATOM 3323 H HG . SER A 1 213 ? 6.935 196.545 38.972 1.00 26.09 ? 519 SER A HG 1 ATOM 3324 N N . CYS A 1 214 ? 5.492 193.068 36.909 1.00 23.22 ? 520 CYS A N 1 ATOM 3325 C CA A CYS A 1 214 ? 6.049 192.679 35.608 0.79 25.63 ? 520 CYS A CA 1 ATOM 3326 C CA B CYS A 1 214 ? 6.097 192.681 35.638 0.21 25.47 ? 520 CYS A CA 1 ATOM 3327 C C . CYS A 1 214 ? 6.380 191.182 35.535 1.00 27.00 ? 520 CYS A C 1 ATOM 3328 O O . CYS A 1 214 ? 7.296 190.770 34.811 1.00 20.85 ? 520 CYS A O 1 ATOM 3329 C CB A CYS A 1 214 ? 7.283 193.527 35.265 0.79 24.32 ? 520 CYS A CB 1 ATOM 3330 C CB B CYS A 1 214 ? 7.394 193.467 35.433 0.21 24.18 ? 520 CYS A CB 1 ATOM 3331 S SG A CYS A 1 214 ? 6.969 195.338 35.147 0.79 22.73 ? 520 CYS A SG 1 ATOM 3332 S SG B CYS A 1 214 ? 8.070 193.340 33.794 0.21 26.08 ? 520 CYS A SG 1 ATOM 3333 H H A CYS A 1 214 ? 4.649 193.237 36.877 0.79 27.86 ? 520 CYS A H 1 ATOM 3334 H H B CYS A 1 214 ? 4.649 193.231 36.861 0.21 27.86 ? 520 CYS A H 1 ATOM 3335 H HA A CYS A 1 214 ? 5.381 192.857 34.928 0.79 30.76 ? 520 CYS A HA 1 ATOM 3336 H HA B CYS A 1 214 ? 5.490 192.917 34.919 0.21 30.57 ? 520 CYS A HA 1 ATOM 3337 H HB2 A CYS A 1 214 ? 7.953 193.390 35.953 0.79 29.18 ? 520 CYS A HB2 1 ATOM 3338 H HB2 B CYS A 1 214 ? 7.221 194.405 35.609 0.21 29.02 ? 520 CYS A HB2 1 ATOM 3339 H HB3 A CYS A 1 214 ? 7.631 193.234 34.409 0.79 29.18 ? 520 CYS A HB3 1 ATOM 3340 H HB3 B CYS A 1 214 ? 8.061 193.135 36.054 0.21 29.02 ? 520 CYS A HB3 1 ATOM 3341 H HG B CYS A 1 214 ? 9.079 193.987 33.736 0.21 31.30 ? 520 CYS A HG 1 ATOM 3342 N N . LEU A 1 215 ? 5.618 190.347 36.241 1.00 17.75 ? 521 LEU A N 1 ATOM 3343 C CA . LEU A 1 215 ? 5.847 188.893 36.161 1.00 25.78 ? 521 LEU A CA 1 ATOM 3344 C C . LEU A 1 215 ? 4.925 188.265 35.115 1.00 19.67 ? 521 LEU A C 1 ATOM 3345 O O . LEU A 1 215 ? 3.780 188.700 34.960 1.00 15.76 ? 521 LEU A O 1 ATOM 3346 C CB . LEU A 1 215 ? 5.627 188.195 37.518 1.00 22.73 ? 521 LEU A CB 1 ATOM 3347 C CG . LEU A 1 215 ? 6.592 188.564 38.649 1.00 28.43 ? 521 LEU A CG 1 ATOM 3348 C CD1 . LEU A 1 215 ? 6.153 187.937 39.982 1.00 27.43 ? 521 LEU A CD1 1 ATOM 3349 C CD2 . LEU A 1 215 ? 8.009 188.139 38.305 1.00 33.68 ? 521 LEU A CD2 1 ATOM 3350 H H . LEU A 1 215 ? 4.976 190.584 36.762 1.00 21.30 ? 521 LEU A H 1 ATOM 3351 H HA . LEU A 1 215 ? 6.764 188.733 35.887 1.00 30.94 ? 521 LEU A HA 1 ATOM 3352 H HB2 . LEU A 1 215 ? 4.732 188.406 37.825 1.00 27.28 ? 521 LEU A HB2 1 ATOM 3353 H HB3 . LEU A 1 215 ? 5.700 187.237 37.380 1.00 27.28 ? 521 LEU A HB3 1 ATOM 3354 H HG . LEU A 1 215 ? 6.590 189.528 38.760 1.00 34.11 ? 521 LEU A HG 1 ATOM 3355 H HD11 . LEU A 1 215 ? 6.784 188.191 40.673 1.00 32.91 ? 521 LEU A HD11 1 ATOM 3356 H HD12 . LEU A 1 215 ? 5.267 188.263 40.207 1.00 32.91 ? 521 LEU A HD12 1 ATOM 3357 H HD13 . LEU A 1 215 ? 6.137 186.972 39.887 1.00 32.91 ? 521 LEU A HD13 1 ATOM 3358 H HD21 . LEU A 1 215 ? 8.598 188.384 39.035 1.00 40.42 ? 521 LEU A HD21 1 ATOM 3359 H HD22 . LEU A 1 215 ? 8.027 187.178 38.172 1.00 40.42 ? 521 LEU A HD22 1 ATOM 3360 H HD23 . LEU A 1 215 ? 8.285 188.590 37.492 1.00 40.42 ? 521 LEU A HD23 1 ATOM 3361 N N . PRO A 1 216 ? 5.415 187.233 34.397 1.00 19.75 ? 522 PRO A N 1 ATOM 3362 C CA . PRO A 1 216 ? 6.776 186.680 34.445 1.00 18.35 ? 522 PRO A CA 1 ATOM 3363 C C . PRO A 1 216 ? 7.835 187.618 33.890 1.00 23.59 ? 522 PRO A C 1 ATOM 3364 O O . PRO A 1 216 ? 8.969 187.610 34.365 1.00 28.40 ? 522 PRO A O 1 ATOM 3365 C CB . PRO A 1 216 ? 6.674 185.415 33.590 1.00 15.66 ? 522 PRO A CB 1 ATOM 3366 C CG . PRO A 1 216 ? 5.247 185.065 33.602 1.00 23.48 ? 522 PRO A CG 1 ATOM 3367 C CD . PRO A 1 216 ? 4.519 186.367 33.611 1.00 22.59 ? 522 PRO A CD 1 ATOM 3368 H HA . PRO A 1 216 ? 7.009 186.435 35.354 1.00 22.02 ? 522 PRO A HA 1 ATOM 3369 H HB2 . PRO A 1 216 ? 6.973 185.605 32.687 1.00 18.79 ? 522 PRO A HB2 1 ATOM 3370 H HB3 . PRO A 1 216 ? 7.204 184.707 33.987 1.00 18.79 ? 522 PRO A HB3 1 ATOM 3371 H HG2 . PRO A 1 216 ? 5.029 184.557 32.805 1.00 28.17 ? 522 PRO A HG2 1 ATOM 3372 H HG3 . PRO A 1 216 ? 5.044 184.553 34.400 1.00 28.17 ? 522 PRO A HG3 1 ATOM 3373 H HD2 . PRO A 1 216 ? 4.422 186.708 32.708 1.00 27.10 ? 522 PRO A HD2 1 ATOM 3374 H HD3 . PRO A 1 216 ? 3.661 186.273 34.054 1.00 27.10 ? 522 PRO A HD3 1 ATOM 3375 N N . ASP A 1 217 ? 7.449 188.431 32.915 1.00 23.19 ? 523 ASP A N 1 ATOM 3376 C CA . ASP A 1 217 ? 8.323 189.460 32.372 1.00 20.39 ? 523 ASP A CA 1 ATOM 3377 C C . ASP A 1 217 ? 7.449 190.439 31.594 1.00 21.54 ? 523 ASP A C 1 ATOM 3378 O O . ASP A 1 217 ? 6.257 190.173 31.367 1.00 22.30 ? 523 ASP A O 1 ATOM 3379 C CB . ASP A 1 217 ? 9.413 188.836 31.492 1.00 25.76 ? 523 ASP A CB 1 ATOM 3380 C CG . ASP A 1 217 ? 8.847 188.176 30.250 1.00 22.25 ? 523 ASP A CG 1 ATOM 3381 O OD1 . ASP A 1 217 ? 8.253 188.894 29.415 1.00 27.07 ? 523 ASP A OD1 1 ATOM 3382 O OD2 . ASP A 1 217 ? 9.003 186.943 30.115 1.00 37.26 ? 523 ASP A OD2 1 ATOM 3383 H H . ASP A 1 217 ? 6.673 188.406 32.545 1.00 27.82 ? 523 ASP A H 1 ATOM 3384 H HA . ASP A 1 217 ? 8.750 189.940 33.099 1.00 24.46 ? 523 ASP A HA 1 ATOM 3385 H HB2 . ASP A 1 217 ? 10.029 189.531 31.210 1.00 30.92 ? 523 ASP A HB2 1 ATOM 3386 H HB3 . ASP A 1 217 ? 9.885 188.160 32.003 1.00 30.92 ? 523 ASP A HB3 1 ATOM 3387 N N . PRO A 1 218 ? 7.983 191.600 31.209 1.00 19.23 ? 524 PRO A N 1 ATOM 3388 C CA . PRO A 1 218 ? 7.083 192.636 30.671 1.00 23.83 ? 524 PRO A CA 1 ATOM 3389 C C . PRO A 1 218 ? 6.393 192.232 29.378 1.00 18.70 ? 524 PRO A C 1 ATOM 3390 O O . PRO A 1 218 ? 5.257 192.653 29.147 1.00 21.64 ? 524 PRO A O 1 ATOM 3391 C CB . PRO A 1 218 ? 7.996 193.859 30.495 1.00 22.71 ? 524 PRO A CB 1 ATOM 3392 C CG . PRO A 1 218 ? 9.358 193.365 30.546 1.00 24.03 ? 524 PRO A CG 1 ATOM 3393 C CD . PRO A 1 218 ? 9.387 192.044 31.247 1.00 22.04 ? 524 PRO A CD 1 ATOM 3394 H HA . PRO A 1 218 ? 6.404 192.850 31.330 1.00 28.59 ? 524 PRO A HA 1 ATOM 3395 H HB2 . PRO A 1 218 ? 7.817 194.274 29.636 1.00 27.26 ? 524 PRO A HB2 1 ATOM 3396 H HB3 . PRO A 1 218 ? 7.836 194.488 31.215 1.00 27.26 ? 524 PRO A HB3 1 ATOM 3397 H HG2 . PRO A 1 218 ? 9.689 193.264 29.639 1.00 28.84 ? 524 PRO A HG2 1 ATOM 3398 H HG3 . PRO A 1 218 ? 9.906 194.005 31.026 1.00 28.84 ? 524 PRO A HG3 1 ATOM 3399 H HD2 . PRO A 1 218 ? 9.952 191.419 30.767 1.00 26.45 ? 524 PRO A HD2 1 ATOM 3400 H HD3 . PRO A 1 218 ? 9.681 192.155 32.165 1.00 26.45 ? 524 PRO A HD3 1 ATOM 3401 N N . ILE A 1 219 ? 7.004 191.376 28.564 1.00 22.88 ? 525 ILE A N 1 ATOM 3402 C CA . ILE A 1 219 ? 6.366 190.925 27.326 1.00 21.82 ? 525 ILE A CA 1 ATOM 3403 C C . ILE A 1 219 ? 5.186 189.996 27.624 1.00 25.05 ? 525 ILE A C 1 ATOM 3404 O O . ILE A 1 219 ? 4.113 190.114 27.022 1.00 23.51 ? 525 ILE A O 1 ATOM 3405 C CB . ILE A 1 219 ? 7.419 190.238 26.445 1.00 24.51 ? 525 ILE A CB 1 ATOM 3406 C CG1 . ILE A 1 219 ? 8.480 191.251 26.005 1.00 19.79 ? 525 ILE A CG1 1 ATOM 3407 C CG2 . ILE A 1 219 ? 6.771 189.542 25.266 1.00 25.13 ? 525 ILE A CG2 1 ATOM 3408 C CD1 . ILE A 1 219 ? 9.773 190.580 25.527 1.00 24.45 ? 525 ILE A CD1 1 ATOM 3409 H H . ILE A 1 219 ? 7.785 191.043 28.702 1.00 27.46 ? 525 ILE A H 1 ATOM 3410 H HA . ILE A 1 219 ? 6.028 191.696 26.845 1.00 26.19 ? 525 ILE A HA 1 ATOM 3411 H HB . ILE A 1 219 ? 7.861 189.562 26.982 1.00 29.41 ? 525 ILE A HB 1 ATOM 3412 H HG12 . ILE A 1 219 ? 8.128 191.780 25.272 1.00 23.75 ? 525 ILE A HG12 1 ATOM 3413 H HG13 . ILE A 1 219 ? 8.700 191.826 26.754 1.00 23.75 ? 525 ILE A HG13 1 ATOM 3414 H HG21 . ILE A 1 219 ? 7.461 189.120 24.731 1.00 30.15 ? 525 ILE A HG21 1 ATOM 3415 H HG22 . ILE A 1 219 ? 6.152 188.872 25.597 1.00 30.15 ? 525 ILE A HG22 1 ATOM 3416 H HG23 . ILE A 1 219 ? 6.295 190.199 24.735 1.00 30.15 ? 525 ILE A HG23 1 ATOM 3417 H HD11 . ILE A 1 219 ? 10.406 191.266 25.262 1.00 29.34 ? 525 ILE A HD11 1 ATOM 3418 H HD12 . ILE A 1 219 ? 10.142 190.053 26.253 1.00 29.34 ? 525 ILE A HD12 1 ATOM 3419 H HD13 . ILE A 1 219 ? 9.570 190.007 24.771 1.00 29.34 ? 525 ILE A HD13 1 ATOM 3420 N N . THR A 1 220 ? 5.363 189.061 28.553 1.00 20.48 ? 526 THR A N 1 ATOM 3421 C CA . THR A 1 220 ? 4.342 188.070 28.866 1.00 20.82 ? 526 THR A CA 1 ATOM 3422 C C . THR A 1 220 ? 3.587 188.371 30.157 1.00 24.67 ? 526 THR A C 1 ATOM 3423 O O . THR A 1 220 ? 2.854 187.507 30.636 1.00 31.16 ? 526 THR A O 1 ATOM 3424 C CB . THR A 1 220 ? 4.990 186.695 28.963 1.00 25.54 ? 526 THR A CB 1 ATOM 3425 O OG1 . THR A 1 220 ? 5.917 186.703 30.054 1.00 27.48 ? 526 THR A OG1 1 ATOM 3426 C CG2 . THR A 1 220 ? 5.727 186.355 27.660 1.00 21.32 ? 526 THR A CG2 1 ATOM 3427 H H . THR A 1 220 ? 6.079 188.980 29.022 1.00 24.58 ? 526 THR A H 1 ATOM 3428 H HA . THR A 1 220 ? 3.696 188.045 28.143 1.00 24.98 ? 526 THR A HA 1 ATOM 3429 H HB . THR A 1 220 ? 4.308 186.023 29.119 1.00 30.65 ? 526 THR A HB 1 ATOM 3430 H HG1 . THR A 1 220 ? 6.286 185.951 30.124 1.00 32.98 ? 526 THR A HG1 1 ATOM 3431 H HG21 . THR A 1 220 ? 6.136 185.479 27.730 1.00 25.59 ? 526 THR A HG21 1 ATOM 3432 H HG22 . THR A 1 220 ? 5.103 186.354 26.917 1.00 25.59 ? 526 THR A HG22 1 ATOM 3433 H HG23 . THR A 1 220 ? 6.419 187.014 27.489 1.00 25.59 ? 526 THR A HG23 1 ATOM 3434 N N . ALA A 1 221 ? 3.731 189.579 30.715 1.00 21.13 ? 527 ALA A N 1 ATOM 3435 C CA . ALA A 1 221 ? 3.171 189.905 32.019 1.00 22.56 ? 527 ALA A CA 1 ATOM 3436 C C . ALA A 1 221 ? 1.714 189.474 32.154 1.00 27.59 ? 527 ALA A C 1 ATOM 3437 O O . ALA A 1 221 ? 0.888 189.750 31.282 1.00 22.17 ? 527 ALA A O 1 ATOM 3438 C CB . ALA A 1 221 ? 3.283 191.411 32.266 1.00 27.00 ? 527 ALA A CB 1 ATOM 3439 H H . ALA A 1 221 ? 4.155 190.231 30.348 1.00 25.36 ? 527 ALA A H 1 ATOM 3440 H HA . ALA A 1 221 ? 3.684 189.449 32.705 1.00 27.07 ? 527 ALA A HA 1 ATOM 3441 H HB1 . ALA A 1 221 ? 2.907 191.616 33.137 1.00 32.40 ? 527 ALA A HB1 1 ATOM 3442 H HB2 . ALA A 1 221 ? 4.218 191.666 32.240 1.00 32.40 ? 527 ALA A HB2 1 ATOM 3443 H HB3 . ALA A 1 221 ? 2.791 191.881 31.575 1.00 32.40 ? 527 ALA A HB3 1 ATOM 3444 N N . TYR A 1 222 ? 1.409 188.806 33.274 1.00 29.02 ? 528 TYR A N 1 ATOM 3445 C CA . TYR A 1 222 ? 0.024 188.551 33.666 1.00 35.12 ? 528 TYR A CA 1 ATOM 3446 C C . TYR A 1 222 ? -0.812 189.819 33.613 1.00 27.88 ? 528 TYR A C 1 ATOM 3447 O O . TYR A 1 222 ? -1.842 189.870 32.934 1.00 32.08 ? 528 TYR A O 1 ATOM 3448 C CB . TYR A 1 222 ? -0.046 187.986 35.088 1.00 30.86 ? 528 TYR A CB 1 ATOM 3449 C CG . TYR A 1 222 ? 0.773 186.764 35.327 1.00 36.16 ? 528 TYR A CG 1 ATOM 3450 C CD1 . TYR A 1 222 ? 0.821 185.741 34.394 1.00 34.00 ? 528 TYR A CD1 1 ATOM 3451 C CD2 . TYR A 1 222 ? 1.505 186.627 36.500 1.00 37.36 ? 528 TYR A CD2 1 ATOM 3452 C CE1 . TYR A 1 222 ? 1.577 184.602 34.628 1.00 37.34 ? 528 TYR A CE1 1 ATOM 3453 C CE2 . TYR A 1 222 ? 2.261 185.499 36.744 1.00 35.42 ? 528 TYR A CE2 1 ATOM 3454 C CZ . TYR A 1 222 ? 2.295 184.492 35.808 1.00 32.89 ? 528 TYR A CZ 1 ATOM 3455 O OH . TYR A 1 222 ? 3.058 183.378 36.052 1.00 44.93 ? 528 TYR A OH 1 ATOM 3456 H H . TYR A 1 222 ? 1.990 188.492 33.824 1.00 34.82 ? 528 TYR A H 1 ATOM 3457 H HA . TYR A 1 222 ? -0.367 187.902 33.060 1.00 42.14 ? 528 TYR A HA 1 ATOM 3458 H HB2 . TYR A 1 222 ? 0.261 188.669 35.705 1.00 37.03 ? 528 TYR A HB2 1 ATOM 3459 H HB3 . TYR A 1 222 ? -0.969 187.762 35.284 1.00 37.03 ? 528 TYR A HB3 1 ATOM 3460 H HD1 . TYR A 1 222 ? 0.335 185.816 33.605 1.00 40.80 ? 528 TYR A HD1 1 ATOM 3461 H HD2 . TYR A 1 222 ? 1.480 187.305 37.136 1.00 44.83 ? 528 TYR A HD2 1 ATOM 3462 H HE1 . TYR A 1 222 ? 1.606 183.920 33.996 1.00 44.81 ? 528 TYR A HE1 1 ATOM 3463 H HE2 . TYR A 1 222 ? 2.747 185.422 37.533 1.00 42.51 ? 528 TYR A HE2 1 ATOM 3464 H HH . TYR A 1 222 ? 2.999 182.843 35.407 1.00 53.91 ? 528 TYR A HH 1 ATOM 3465 N N . ASP A 1 223 ? -0.388 190.847 34.359 1.00 26.91 ? 529 ASP A N 1 ATOM 3466 C CA . ASP A 1 223 ? -1.141 192.090 34.539 1.00 26.26 ? 529 ASP A CA 1 ATOM 3467 C C . ASP A 1 223 ? -0.347 193.275 33.998 1.00 29.75 ? 529 ASP A C 1 ATOM 3468 O O . ASP A 1 223 ? 0.420 193.915 34.743 1.00 25.87 ? 529 ASP A O 1 ATOM 3469 C CB . ASP A 1 223 ? -1.472 192.295 36.016 1.00 29.06 ? 529 ASP A CB 1 ATOM 3470 C CG . ASP A 1 223 ? -2.148 193.624 36.281 1.00 38.91 ? 529 ASP A CG 1 ATOM 3471 O OD1 . ASP A 1 223 ? -2.957 194.052 35.433 1.00 41.10 ? 529 ASP A OD1 1 ATOM 3472 O OD2 . ASP A 1 223 ? -1.879 194.239 37.338 1.00 49.63 ? 529 ASP A OD2 1 ATOM 3473 H H . ASP A 1 223 ? 0.359 190.844 34.785 1.00 32.29 ? 529 ASP A H 1 ATOM 3474 H HA . ASP A 1 223 ? -1.974 192.033 34.046 1.00 31.51 ? 529 ASP A HA 1 ATOM 3475 H HB2 . ASP A 1 223 ? -2.070 191.589 36.307 1.00 34.87 ? 529 ASP A HB2 1 ATOM 3476 H HB3 . ASP A 1 223 ? -0.650 192.267 36.531 1.00 34.87 ? 529 ASP A HB3 1 ATOM 3477 N N . PRO A 1 224 ? -0.520 193.633 32.719 1.00 24.41 ? 530 PRO A N 1 ATOM 3478 C CA . PRO A 1 224 ? 0.234 194.777 32.186 1.00 21.12 ? 530 PRO A CA 1 ATOM 3479 C C . PRO A 1 224 ? -0.039 196.066 32.936 1.00 24.66 ? 530 PRO A C 1 ATOM 3480 O O . PRO A 1 224 ? 0.854 196.918 33.051 1.00 18.01 ? 530 PRO A O 1 ATOM 3481 C CB . PRO A 1 224 ? -0.241 194.870 30.727 1.00 26.84 ? 530 PRO A CB 1 ATOM 3482 C CG . PRO A 1 224 ? -0.889 193.585 30.427 1.00 26.61 ? 530 PRO A CG 1 ATOM 3483 C CD . PRO A 1 224 ? -1.451 193.087 31.723 1.00 24.72 ? 530 PRO A CD 1 ATOM 3484 H HA . PRO A 1 224 ? 1.186 194.591 32.203 1.00 25.34 ? 530 PRO A HA 1 ATOM 3485 H HB2 . PRO A 1 224 ? -0.874 195.599 30.638 1.00 32.20 ? 530 PRO A HB2 1 ATOM 3486 H HB3 . PRO A 1 224 ? 0.523 195.009 30.146 1.00 32.20 ? 530 PRO A HB3 1 ATOM 3487 H HG2 . PRO A 1 224 ? -1.599 193.724 29.781 1.00 31.93 ? 530 PRO A HG2 1 ATOM 3488 H HG3 . PRO A 1 224 ? -0.231 192.963 30.081 1.00 31.93 ? 530 PRO A HG3 1 ATOM 3489 H HD2 . PRO A 1 224 ? -2.343 193.439 31.864 1.00 29.66 ? 530 PRO A HD2 1 ATOM 3490 H HD3 . PRO A 1 224 ? -1.441 192.117 31.746 1.00 29.66 ? 530 PRO A HD3 1 ATOM 3491 N N . ARG A 1 225 ? -1.262 196.241 33.437 1.00 21.91 ? 531 ARG A N 1 ATOM 3492 C CA . ARG A 1 225 ? -1.607 197.475 34.122 1.00 23.64 ? 531 ARG A CA 1 ATOM 3493 C C . ARG A 1 225 ? -0.667 197.760 35.286 1.00 27.69 ? 531 ARG A C 1 ATOM 3494 O O . ARG A 1 225 ? -0.366 198.925 35.564 1.00 24.36 ? 531 ARG A O 1 ATOM 3495 C CB . ARG A 1 225 ? -3.045 197.401 34.617 1.00 23.46 ? 531 ARG A CB 1 ATOM 3496 C CG . ARG A 1 225 ? -3.566 198.675 35.195 1.00 26.24 ? 531 ARG A CG 1 ATOM 3497 C CD . ARG A 1 225 ? -3.384 199.865 34.220 1.00 34.47 ? 531 ARG A CD 1 ATOM 3498 N NE . ARG A 1 225 ? -3.910 201.086 34.821 1.00 37.15 ? 531 ARG A NE 1 ATOM 3499 C CZ . ARG A 1 225 ? -5.202 201.386 34.858 1.00 36.22 ? 531 ARG A CZ 1 ATOM 3500 N NH1 . ARG A 1 225 ? -6.097 200.567 34.296 1.00 29.02 ? 531 ARG A NH1 1 ATOM 3501 N NH2 . ARG A 1 225 ? -5.593 202.499 35.455 1.00 32.01 ? 531 ARG A NH2 1 ATOM 3502 H H . ARG A 1 225 ? -1.899 195.665 33.392 1.00 26.30 ? 531 ARG A H 1 ATOM 3503 H HA . ARG A 1 225 ? -1.542 198.214 33.496 1.00 28.37 ? 531 ARG A HA 1 ATOM 3504 H HB2 . ARG A 1 225 ? -3.617 197.159 33.872 1.00 28.15 ? 531 ARG A HB2 1 ATOM 3505 H HB3 . ARG A 1 225 ? -3.101 196.720 35.306 1.00 28.15 ? 531 ARG A HB3 1 ATOM 3506 H HG2 . ARG A 1 225 ? -4.513 198.578 35.381 1.00 31.49 ? 531 ARG A HG2 1 ATOM 3507 H HG3 . ARG A 1 225 ? -3.083 198.876 36.012 1.00 31.49 ? 531 ARG A HG3 1 ATOM 3508 H HD2 . ARG A 1 225 ? -2.441 199.993 34.035 1.00 41.36 ? 531 ARG A HD2 1 ATOM 3509 H HD3 . ARG A 1 225 ? -3.872 199.691 33.400 1.00 41.36 ? 531 ARG A HD3 1 ATOM 3510 H HE . ARG A 1 225 ? -3.348 201.696 35.050 1.00 44.58 ? 531 ARG A HE 1 ATOM 3511 H HH11 . ARG A 1 225 ? -5.836 199.840 33.918 1.00 34.83 ? 531 ARG A HH11 1 ATOM 3512 H HH12 . ARG A 1 225 ? -6.933 200.766 34.317 1.00 34.83 ? 531 ARG A HH12 1 ATOM 3513 H HH21 . ARG A 1 225 ? -5.011 203.026 35.807 1.00 38.41 ? 531 ARG A HH21 1 ATOM 3514 H HH22 . ARG A 1 225 ? -6.427 202.709 35.470 1.00 38.41 ? 531 ARG A HH22 1 ATOM 3515 N N . SER A 1 226 ? -0.176 196.726 35.966 1.00 22.81 ? 532 SER A N 1 ATOM 3516 C CA . SER A 1 226 ? 0.673 196.938 37.134 1.00 31.68 ? 532 SER A CA 1 ATOM 3517 C C . SER A 1 226 ? 2.153 196.890 36.791 1.00 26.55 ? 532 SER A C 1 ATOM 3518 O O . SER A 1 226 ? 2.990 197.061 37.684 1.00 22.95 ? 532 SER A O 1 ATOM 3519 C CB . SER A 1 226 ? 0.357 195.906 38.223 1.00 22.42 ? 532 SER A CB 1 ATOM 3520 O OG . SER A 1 226 ? 0.700 194.603 37.790 1.00 41.62 ? 532 SER A OG 1 ATOM 3521 H H . SER A 1 226 ? -0.317 195.900 35.773 1.00 27.37 ? 532 SER A H 1 ATOM 3522 H HA . SER A 1 226 ? 0.485 197.817 37.498 1.00 38.02 ? 532 SER A HA 1 ATOM 3523 H HB2 . SER A 1 226 ? 0.867 196.120 39.019 1.00 26.91 ? 532 SER A HB2 1 ATOM 3524 H HB3 . SER A 1 226 ? -0.593 195.934 38.419 1.00 26.91 ? 532 SER A HB3 1 ATOM 3525 H HG . SER A 1 226 ? 0.265 194.406 37.099 1.00 49.94 ? 532 SER A HG 1 ATOM 3526 N N . CYS A 1 227 ? 2.490 196.682 35.522 1.00 19.86 ? 533 CYS A N 1 ATOM 3527 C CA . CYS A 1 227 ? 3.873 196.731 35.073 1.00 20.10 ? 533 CYS A CA 1 ATOM 3528 C C . CYS A 1 227 ? 4.168 198.131 34.546 1.00 25.15 ? 533 CYS A C 1 ATOM 3529 O O . CYS A 1 227 ? 3.448 198.645 33.679 1.00 20.35 ? 533 CYS A O 1 ATOM 3530 C CB . CYS A 1 227 ? 4.129 195.663 33.997 1.00 21.57 ? 533 CYS A CB 1 ATOM 3531 S SG . CYS A 1 227 ? 5.832 195.550 33.448 1.00 20.90 ? 533 CYS A SG 1 ATOM 3532 H H . CYS A 1 227 ? 1.928 196.510 34.895 1.00 23.84 ? 533 CYS A H 1 ATOM 3533 H HA . CYS A 1 227 ? 4.462 196.556 35.824 1.00 24.12 ? 533 CYS A HA 1 ATOM 3534 H HB2 . CYS A 1 227 ? 3.877 194.797 34.354 1.00 25.89 ? 533 CYS A HB2 1 ATOM 3535 H HB3 . CYS A 1 227 ? 3.583 195.868 33.222 1.00 25.89 ? 533 CYS A HB3 1 ATOM 3536 N N . SER A 1 228 ? 5.213 198.757 35.082 1.00 20.96 ? 534 SER A N 1 ATOM 3537 C CA . SER A 1 228 ? 5.490 200.138 34.711 1.00 21.36 ? 534 SER A CA 1 ATOM 3538 C C . SER A 1 228 ? 6.125 200.251 33.334 1.00 19.94 ? 534 SER A C 1 ATOM 3539 O O . SER A 1 228 ? 6.196 201.355 32.789 1.00 20.21 ? 534 SER A O 1 ATOM 3540 C CB . SER A 1 228 ? 6.389 200.792 35.756 1.00 15.51 ? 534 SER A CB 1 ATOM 3541 O OG . SER A 1 228 ? 5.633 201.023 36.930 1.00 20.96 ? 534 SER A OG 1 ATOM 3542 H H . SER A 1 228 ? 5.763 198.414 35.647 1.00 25.15 ? 534 SER A H 1 ATOM 3543 H HA . SER A 1 228 ? 4.654 200.629 34.692 1.00 25.64 ? 534 SER A HA 1 ATOM 3544 H HB2 . SER A 1 228 ? 7.129 200.199 35.961 1.00 18.61 ? 534 SER A HB2 1 ATOM 3545 H HB3 . SER A 1 228 ? 6.719 201.638 35.413 1.00 18.61 ? 534 SER A HB3 1 ATOM 3546 H HG . SER A 1 228 ? 6.114 201.383 37.516 1.00 25.16 ? 534 SER A HG 1 ATOM 3547 N N . GLN A 1 229 ? 6.593 199.143 32.774 1.00 18.48 ? 535 GLN A N 1 ATOM 3548 C CA . GLN A 1 229 ? 7.083 199.120 31.406 1.00 16.82 ? 535 GLN A CA 1 ATOM 3549 C C . GLN A 1 229 ? 5.883 198.952 30.482 1.00 18.48 ? 535 GLN A C 1 ATOM 3550 O O . GLN A 1 229 ? 5.140 197.969 30.597 1.00 20.09 ? 535 GLN A O 1 ATOM 3551 C CB . GLN A 1 229 ? 8.092 197.985 31.233 1.00 16.12 ? 535 GLN A CB 1 ATOM 3552 C CG . GLN A 1 229 ? 9.212 198.044 32.258 1.00 18.50 ? 535 GLN A CG 1 ATOM 3553 C CD . GLN A 1 229 ? 10.199 196.908 32.126 1.00 15.71 ? 535 GLN A CD 1 ATOM 3554 O OE1 . GLN A 1 229 ? 10.711 196.627 31.038 1.00 19.26 ? 535 GLN A OE1 1 ATOM 3555 N NE2 . GLN A 1 229 ? 10.464 196.241 33.233 1.00 15.03 ? 535 GLN A NE2 1 ATOM 3556 H H . GLN A 1 229 ? 6.637 198.382 33.172 1.00 22.18 ? 535 GLN A H 1 ATOM 3557 H HA . GLN A 1 229 ? 7.520 199.961 31.200 1.00 20.18 ? 535 GLN A HA 1 ATOM 3558 H HB2 . GLN A 1 229 ? 7.635 197.136 31.335 1.00 19.34 ? 535 GLN A HB2 1 ATOM 3559 H HB3 . GLN A 1 229 ? 8.489 198.046 30.350 1.00 19.34 ? 535 GLN A HB3 1 ATOM 3560 H HG2 . GLN A 1 229 ? 9.698 198.876 32.146 1.00 22.20 ? 535 GLN A HG2 1 ATOM 3561 H HG3 . GLN A 1 229 ? 8.827 198.003 33.147 1.00 22.20 ? 535 GLN A HG3 1 ATOM 3562 H HE21 . GLN A 1 229 ? 10.081 196.462 33.971 1.00 18.03 ? 535 GLN A HE21 1 ATOM 3563 H HE22 . GLN A 1 229 ? 11.019 195.584 33.216 1.00 18.03 ? 535 GLN A HE22 1 ATOM 3564 N N . LYS A 1 230 ? 5.676 199.917 29.594 1.00 12.94 ? 536 LYS A N 1 ATOM 3565 C CA . LYS A 1 230 ? 4.478 199.983 28.774 1.00 18.51 ? 536 LYS A CA 1 ATOM 3566 C C . LYS A 1 230 ? 4.822 199.728 27.306 1.00 20.98 ? 536 LYS A C 1 ATOM 3567 O O . LYS A 1 230 ? 5.764 200.318 26.762 1.00 17.65 ? 536 LYS A O 1 ATOM 3568 C CB . LYS A 1 230 ? 3.788 201.341 28.919 1.00 16.99 ? 536 LYS A CB 1 ATOM 3569 C CG . LYS A 1 230 ? 3.508 201.777 30.347 1.00 18.49 ? 536 LYS A CG 1 ATOM 3570 C CD . LYS A 1 230 ? 2.642 200.775 31.100 1.00 16.57 ? 536 LYS A CD 1 ATOM 3571 C CE . LYS A 1 230 ? 2.074 201.375 32.361 1.00 14.05 ? 536 LYS A CE 1 ATOM 3572 N NZ . LYS A 1 230 ? 1.250 200.375 33.114 1.00 28.74 ? 536 LYS A NZ 1 ATOM 3573 H H . LYS A 1 230 ? 6.229 200.558 29.446 1.00 15.53 ? 536 LYS A H 1 ATOM 3574 H HA . LYS A 1 230 ? 3.856 199.296 29.062 1.00 22.22 ? 536 LYS A HA 1 ATOM 3575 H HB2 . LYS A 1 230 ? 4.352 202.018 28.513 1.00 20.39 ? 536 LYS A HB2 1 ATOM 3576 H HB3 . LYS A 1 230 ? 2.938 201.306 28.453 1.00 20.39 ? 536 LYS A HB3 1 ATOM 3577 H HG2 . LYS A 1 230 ? 4.349 201.865 30.822 1.00 22.19 ? 536 LYS A HG2 1 ATOM 3578 H HG3 . LYS A 1 230 ? 3.042 202.628 30.334 1.00 22.19 ? 536 LYS A HG3 1 ATOM 3579 H HD2 . LYS A 1 230 ? 1.903 200.501 30.534 1.00 19.88 ? 536 LYS A HD2 1 ATOM 3580 H HD3 . LYS A 1 230 ? 3.180 200.007 31.345 1.00 19.88 ? 536 LYS A HD3 1 ATOM 3581 H HE2 . LYS A 1 230 ? 2.800 201.666 32.935 1.00 16.85 ? 536 LYS A HE2 1 ATOM 3582 H HE3 . LYS A 1 230 ? 1.505 202.127 32.131 1.00 16.85 ? 536 LYS A HE3 1 ATOM 3583 H HZ1 . LYS A 1 230 ? 0.923 200.746 33.854 1.00 34.49 ? 536 LYS A HZ1 1 ATOM 3584 H HZ2 . LYS A 1 230 ? 0.574 200.096 32.608 1.00 34.49 ? 536 LYS A HZ2 1 ATOM 3585 H HZ3 . LYS A 1 230 ? 1.752 199.675 33.339 1.00 34.49 ? 536 LYS A HZ3 1 ATOM 3586 N N . LYS A 1 231 ? 4.057 198.850 26.674 1.00 19.50 ? 537 LYS A N 1 ATOM 3587 C CA . LYS A 1 231 ? 4.275 198.572 25.264 1.00 30.25 ? 537 LYS A CA 1 ATOM 3588 C C . LYS A 1 231 ? 4.172 199.859 24.460 1.00 23.60 ? 537 LYS A C 1 ATOM 3589 O O . LYS A 1 231 ? 3.304 200.697 24.723 1.00 22.50 ? 537 LYS A O 1 ATOM 3590 C CB . LYS A 1 231 ? 3.243 197.578 24.752 1.00 32.64 ? 537 LYS A CB 1 ATOM 3591 C CG . LYS A 1 231 ? 3.243 196.218 25.425 1.00 30.69 ? 537 LYS A CG 1 ATOM 3592 C CD . LYS A 1 231 ? 2.019 195.406 24.967 1.00 42.03 ? 537 LYS A CD 1 ATOM 3593 C CE . LYS A 1 231 ? 1.914 195.293 23.439 1.00 52.24 ? 537 LYS A CE 1 ATOM 3594 N NZ . LYS A 1 231 ? 0.529 194.985 23.006 1.00 56.88 ? 537 LYS A NZ 1 ATOM 3595 H H . LYS A 1 231 ? 3.413 198.408 27.032 1.00 23.40 ? 537 LYS A H 1 ATOM 3596 H HA . LYS A 1 231 ? 5.160 198.195 25.138 1.00 36.30 ? 537 LYS A HA 1 ATOM 3597 H HB2 . LYS A 1 231 ? 2.361 197.962 24.876 1.00 39.17 ? 537 LYS A HB2 1 ATOM 3598 H HB3 . LYS A 1 231 ? 3.402 197.433 23.806 1.00 39.17 ? 537 LYS A HB3 1 ATOM 3599 H HG2 . LYS A 1 231 ? 4.046 195.733 25.178 1.00 36.83 ? 537 LYS A HG2 1 ATOM 3600 H HG3 . LYS A 1 231 ? 3.196 196.332 26.387 1.00 36.83 ? 537 LYS A HG3 1 ATOM 3601 H HD2 . LYS A 1 231 ? 2.083 194.508 25.329 1.00 50.43 ? 537 LYS A HD2 1 ATOM 3602 H HD3 . LYS A 1 231 ? 1.214 195.838 25.291 1.00 50.43 ? 537 LYS A HD3 1 ATOM 3603 H HE2 . LYS A 1 231 ? 2.177 196.137 23.037 1.00 62.69 ? 537 LYS A HE2 1 ATOM 3604 H HE3 . LYS A 1 231 ? 2.494 194.580 23.130 1.00 62.69 ? 537 LYS A HE3 1 ATOM 3605 H HZ1 . LYS A 1 231 ? 0.494 194.925 22.118 1.00 68.26 ? 537 LYS A HZ1 1 ATOM 3606 H HZ2 . LYS A 1 231 ? 0.265 194.211 23.358 1.00 68.26 ? 537 LYS A HZ2 1 ATOM 3607 H HZ3 . LYS A 1 231 ? -0.024 195.629 23.274 1.00 68.26 ? 537 LYS A HZ3 1 ATOM 3608 N N . SER A 1 232 ? 5.071 200.025 23.488 1.00 23.69 ? 538 SER A N 1 ATOM 3609 C CA . SER A 1 232 ? 5.001 201.164 22.571 1.00 30.23 ? 538 SER A CA 1 ATOM 3610 C C . SER A 1 232 ? 5.449 200.756 21.175 1.00 19.11 ? 538 SER A C 1 ATOM 3611 O O . SER A 1 232 ? 6.553 200.236 20.990 1.00 23.17 ? 538 SER A O 1 ATOM 3612 C CB . SER A 1 232 ? 5.844 202.344 23.070 1.00 28.77 ? 538 SER A CB 1 ATOM 3613 O OG . SER A 1 232 ? 7.131 201.929 23.466 1.00 34.87 ? 538 SER A OG 1 ATOM 3614 H H . SER A 1 232 ? 5.730 199.493 23.339 1.00 28.43 ? 538 SER A H 1 ATOM 3615 H HA . SER A 1 232 ? 4.079 201.462 22.512 1.00 36.27 ? 538 SER A HA 1 ATOM 3616 H HB2 . SER A 1 232 ? 5.930 202.993 22.354 1.00 34.53 ? 538 SER A HB2 1 ATOM 3617 H HB3 . SER A 1 232 ? 5.398 202.749 23.830 1.00 34.53 ? 538 SER A HB3 1 ATOM 3618 H HG . SER A 1 232 ? 7.532 201.577 22.817 1.00 41.84 ? 538 SER A HG 1 ATOM 3619 N N . LEU A 1 233 ? 4.586 200.997 20.205 1.00 25.63 ? 539 LEU A N 1 ATOM 3620 C CA . LEU A 1 233 ? 4.950 200.919 18.798 1.00 27.12 ? 539 LEU A CA 1 ATOM 3621 C C . LEU A 1 233 ? 5.690 202.184 18.388 1.00 20.75 ? 539 LEU A C 1 ATOM 3622 O O . LEU A 1 233 ? 5.342 203.284 18.821 1.00 18.20 ? 539 LEU A O 1 ATOM 3623 C CB . LEU A 1 233 ? 3.693 200.750 17.948 1.00 26.40 ? 539 LEU A CB 1 ATOM 3624 C CG . LEU A 1 233 ? 2.832 199.560 18.369 1.00 33.66 ? 539 LEU A CG 1 ATOM 3625 C CD1 . LEU A 1 233 ? 1.456 199.646 17.740 1.00 40.88 ? 539 LEU A CD1 1 ATOM 3626 C CD2 . LEU A 1 233 ? 3.522 198.262 17.977 1.00 24.46 ? 539 LEU A CD2 1 ATOM 3627 H H . LEU A 1 233 ? 3.764 201.213 20.336 1.00 30.76 ? 539 LEU A H 1 ATOM 3628 H HA . LEU A 1 233 ? 5.531 200.156 18.652 1.00 32.55 ? 539 LEU A HA 1 ATOM 3629 H HB2 . LEU A 1 233 ? 3.152 201.552 18.025 1.00 31.68 ? 539 LEU A HB2 1 ATOM 3630 H HB3 . LEU A 1 233 ? 3.955 200.616 17.023 1.00 31.68 ? 539 LEU A HB3 1 ATOM 3631 H HG . LEU A 1 233 ? 2.726 199.568 19.333 1.00 40.39 ? 539 LEU A HG 1 ATOM 3632 H HD11 . LEU A 1 233 ? 0.931 198.880 18.023 1.00 49.05 ? 539 LEU A HD11 1 ATOM 3633 H HD12 . LEU A 1 233 ? 1.027 200.466 18.030 1.00 49.05 ? 539 LEU A HD12 1 ATOM 3634 H HD13 . LEU A 1 233 ? 1.550 199.644 16.775 1.00 49.05 ? 539 LEU A HD13 1 ATOM 3635 H HD21 . LEU A 1 233 ? 2.966 197.515 18.250 1.00 29.35 ? 539 LEU A HD21 1 ATOM 3636 H HD22 . LEU A 1 233 ? 3.646 198.249 17.015 1.00 29.35 ? 539 LEU A HD22 1 ATOM 3637 H HD23 . LEU A 1 233 ? 4.382 198.215 18.423 1.00 29.35 ? 539 LEU A HD23 1 ATOM 3638 N N . VAL A 1 234 ? 6.717 202.036 17.550 1.00 16.36 ? 540 VAL A N 1 ATOM 3639 C CA . VAL A 1 234 ? 7.431 203.213 17.079 1.00 20.93 ? 540 VAL A CA 1 ATOM 3640 C C . VAL A 1 234 ? 6.518 203.991 16.138 1.00 19.68 ? 540 VAL A C 1 ATOM 3641 O O . VAL A 1 234 ? 5.872 203.416 15.254 1.00 24.98 ? 540 VAL A O 1 ATOM 3642 C CB . VAL A 1 234 ? 8.753 202.824 16.397 1.00 18.05 ? 540 VAL A CB 1 ATOM 3643 C CG1 . VAL A 1 234 ? 9.717 202.195 17.387 1.00 19.22 ? 540 VAL A CG1 1 ATOM 3644 C CG2 . VAL A 1 234 ? 8.516 201.875 15.230 1.00 24.52 ? 540 VAL A CG2 1 ATOM 3645 H H . VAL A 1 234 ? 7.010 201.285 17.248 1.00 19.63 ? 540 VAL A H 1 ATOM 3646 H HA . VAL A 1 234 ? 7.639 203.783 17.836 1.00 25.12 ? 540 VAL A HA 1 ATOM 3647 H HB . VAL A 1 234 ? 9.171 203.626 16.046 1.00 21.66 ? 540 VAL A HB 1 ATOM 3648 H HG11 . VAL A 1 234 ? 10.537 201.963 16.924 1.00 23.07 ? 540 VAL A HG11 1 ATOM 3649 H HG12 . VAL A 1 234 ? 9.905 202.833 18.093 1.00 23.07 ? 540 VAL A HG12 1 ATOM 3650 H HG13 . VAL A 1 234 ? 9.310 201.398 17.760 1.00 23.07 ? 540 VAL A HG13 1 ATOM 3651 H HG21 . VAL A 1 234 ? 9.370 201.652 14.826 1.00 29.42 ? 540 VAL A HG21 1 ATOM 3652 H HG22 . VAL A 1 234 ? 8.086 201.070 15.560 1.00 29.42 ? 540 VAL A HG22 1 ATOM 3653 H HG23 . VAL A 1 234 ? 7.946 202.312 14.578 1.00 29.42 ? 540 VAL A HG23 1 ATOM 3654 N N . GLY A 1 235 ? 6.410 205.282 16.354 1.00 26.64 ? 541 GLY A N 1 ATOM 3655 C CA . GLY A 1 235 ? 5.786 206.129 15.359 1.00 17.08 ? 541 GLY A CA 1 ATOM 3656 C C . GLY A 1 235 ? 6.784 206.567 14.311 1.00 18.95 ? 541 GLY A C 1 ATOM 3657 O O . GLY A 1 235 ? 7.987 206.353 14.445 1.00 19.41 ? 541 GLY A O 1 ATOM 3658 H H . GLY A 1 235 ? 6.684 205.691 17.059 1.00 31.97 ? 541 GLY A H 1 ATOM 3659 H HA2 . GLY A 1 235 ? 5.067 205.646 14.923 1.00 20.50 ? 541 GLY A HA2 1 ATOM 3660 H HA3 . GLY A 1 235 ? 5.417 206.918 15.787 1.00 20.50 ? 541 GLY A HA3 1 ATOM 3661 N N . VAL A 1 236 ? 6.263 207.199 13.255 1.00 19.84 ? 542 VAL A N 1 ATOM 3662 C CA . VAL A 1 236 ? 7.126 207.789 12.239 1.00 15.05 ? 542 VAL A CA 1 ATOM 3663 C C . VAL A 1 236 ? 8.143 208.710 12.900 1.00 15.04 ? 542 VAL A C 1 ATOM 3664 O O . VAL A 1 236 ? 7.794 209.572 13.716 1.00 21.29 ? 542 VAL A O 1 ATOM 3665 C CB . VAL A 1 236 ? 6.275 208.533 11.191 1.00 24.50 ? 542 VAL A CB 1 ATOM 3666 C CG1 . VAL A 1 236 ? 7.167 209.269 10.189 1.00 23.92 ? 542 VAL A CG1 1 ATOM 3667 C CG2 . VAL A 1 236 ? 5.355 207.563 10.445 1.00 18.98 ? 542 VAL A CG2 1 ATOM 3668 H H . VAL A 1 236 ? 5.422 207.298 13.108 1.00 23.81 ? 542 VAL A H 1 ATOM 3669 H HA . VAL A 1 236 ? 7.610 207.081 11.785 1.00 18.06 ? 542 VAL A HA 1 ATOM 3670 H HB . VAL A 1 236 ? 5.720 209.190 11.640 1.00 29.40 ? 542 VAL A HB 1 ATOM 3671 H HG11 . VAL A 1 236 ? 6.606 209.727 9.544 1.00 28.70 ? 542 VAL A HG11 1 ATOM 3672 H HG12 . VAL A 1 236 ? 7.714 209.912 10.667 1.00 28.70 ? 542 VAL A HG12 1 ATOM 3673 H HG13 . VAL A 1 236 ? 7.733 208.624 9.737 1.00 28.70 ? 542 VAL A HG13 1 ATOM 3674 H HG21 . VAL A 1 236 ? 4.834 208.059 9.794 1.00 22.78 ? 542 VAL A HG21 1 ATOM 3675 H HG22 . VAL A 1 236 ? 5.899 206.897 9.995 1.00 22.78 ? 542 VAL A HG22 1 ATOM 3676 H HG23 . VAL A 1 236 ? 4.765 207.133 11.084 1.00 22.78 ? 542 VAL A HG23 1 ATOM 3677 N N . GLY A 1 237 ? 9.412 208.538 12.530 1.00 19.07 ? 543 GLY A N 1 ATOM 3678 C CA . GLY A 1 237 ? 10.494 209.380 13.007 1.00 18.68 ? 543 GLY A CA 1 ATOM 3679 C C . GLY A 1 237 ? 11.081 208.979 14.350 1.00 23.73 ? 543 GLY A C 1 ATOM 3680 O O . GLY A 1 237 ? 12.050 209.610 14.800 1.00 18.81 ? 543 GLY A O 1 ATOM 3681 H H . GLY A 1 237 ? 9.671 207.922 11.989 1.00 22.89 ? 543 GLY A H 1 ATOM 3682 H HA2 . GLY A 1 237 ? 11.211 209.369 12.353 1.00 22.41 ? 543 GLY A HA2 1 ATOM 3683 H HA3 . GLY A 1 237 ? 10.172 210.292 13.082 1.00 22.41 ? 543 GLY A HA3 1 ATOM 3684 N N . GLU A 1 238 ? 10.542 207.948 14.994 1.00 12.84 ? 544 GLU A N 1 ATOM 3685 C CA . GLU A 1 238 ? 10.972 207.546 16.326 1.00 22.98 ? 544 GLU A CA 1 ATOM 3686 C C . GLU A 1 238 ? 11.864 206.310 16.297 1.00 15.71 ? 544 GLU A C 1 ATOM 3687 O O . GLU A 1 238 ? 11.874 205.522 15.343 1.00 14.19 ? 544 GLU A O 1 ATOM 3688 C CB . GLU A 1 238 ? 9.765 207.269 17.219 1.00 20.34 ? 544 GLU A CB 1 ATOM 3689 C CG . GLU A 1 238 ? 8.760 208.409 17.270 1.00 20.38 ? 544 GLU A CG 1 ATOM 3690 C CD . GLU A 1 238 ? 7.565 208.052 18.112 1.00 29.89 ? 544 GLU A CD 1 ATOM 3691 O OE1 . GLU A 1 238 ? 7.543 206.908 18.630 1.00 32.00 ? 544 GLU A OE1 1 ATOM 3692 O OE2 . GLU A 1 238 ? 6.659 208.906 18.262 1.00 39.40 ? 544 GLU A OE2 1 ATOM 3693 H H . GLU A 1 238 ? 9.914 207.457 14.672 1.00 15.41 ? 544 GLU A H 1 ATOM 3694 H HA . GLU A 1 238 ? 11.479 208.270 16.725 1.00 27.58 ? 544 GLU A HA 1 ATOM 3695 H HB2 . GLU A 1 238 ? 9.305 206.483 16.885 1.00 24.40 ? 544 GLU A HB2 1 ATOM 3696 H HB3 . GLU A 1 238 ? 10.076 207.108 18.123 1.00 24.40 ? 544 GLU A HB3 1 ATOM 3697 H HG2 . GLU A 1 238 ? 9.182 209.191 17.657 1.00 24.46 ? 544 GLU A HG2 1 ATOM 3698 H HG3 . GLU A 1 238 ? 8.451 208.603 16.371 1.00 24.46 ? 544 GLU A HG3 1 ATOM 3699 N N . HIS A 1 239 ? 12.623 206.162 17.372 1.00 15.47 ? 545 HIS A N 1 ATOM 3700 C CA . HIS A 1 239 ? 13.388 204.962 17.651 1.00 14.95 ? 545 HIS A CA 1 ATOM 3701 C C . HIS A 1 239 ? 12.725 204.165 18.765 1.00 16.26 ? 545 HIS A C 1 ATOM 3702 O O . HIS A 1 239 ? 11.897 204.674 19.528 1.00 14.20 ? 545 HIS A O 1 ATOM 3703 C CB . HIS A 1 239 ? 14.829 205.315 18.033 1.00 16.78 ? 545 HIS A CB 1 ATOM 3704 C CG . HIS A 1 239 ? 15.650 205.800 16.883 1.00 15.88 ? 545 HIS A CG 1 ATOM 3705 N ND1 . HIS A 1 239 ? 15.531 207.073 16.366 1.00 16.83 ? 545 HIS A ND1 1 ATOM 3706 C CD2 . HIS A 1 239 ? 16.576 205.168 16.122 1.00 17.55 ? 545 HIS A CD2 1 ATOM 3707 C CE1 . HIS A 1 239 ? 16.368 207.214 15.353 1.00 17.88 ? 545 HIS A CE1 1 ATOM 3708 N NE2 . HIS A 1 239 ? 17.007 206.068 15.177 1.00 18.58 ? 545 HIS A NE2 1 ATOM 3709 H H . HIS A 1 239 ? 12.712 206.768 17.975 1.00 18.56 ? 545 HIS A H 1 ATOM 3710 H HA . HIS A 1 239 ? 13.413 204.408 16.856 1.00 17.94 ? 545 HIS A HA 1 ATOM 3711 H HB2 . HIS A 1 239 ? 14.814 206.015 18.704 1.00 20.14 ? 545 HIS A HB2 1 ATOM 3712 H HB3 . HIS A 1 239 ? 15.260 204.524 18.393 1.00 20.14 ? 545 HIS A HB3 1 ATOM 3713 H HD2 . HIS A 1 239 ? 16.868 204.291 16.223 1.00 21.06 ? 545 HIS A HD2 1 ATOM 3714 H HE1 . HIS A 1 239 ? 16.478 207.983 14.841 1.00 21.46 ? 545 HIS A HE1 1 ATOM 3715 H HE2 . HIS A 1 239 ? 17.604 205.916 14.577 1.00 22.29 ? 545 HIS A HE2 1 ATOM 3716 N N . CYS A 1 240 ? 13.095 202.889 18.827 1.00 17.05 ? 546 CYS A N 1 ATOM 3717 C CA . CYS A 1 240 ? 12.611 202.001 19.871 1.00 16.01 ? 546 CYS A CA 1 ATOM 3718 C C . CYS A 1 240 ? 12.757 202.657 21.236 1.00 15.08 ? 546 CYS A C 1 ATOM 3719 O O . CYS A 1 240 ? 13.838 203.120 21.601 1.00 12.87 ? 546 CYS A O 1 ATOM 3720 C CB . CYS A 1 240 ? 13.400 200.693 19.838 1.00 15.18 ? 546 CYS A CB 1 ATOM 3721 S SG . CYS A 1 240 ? 12.855 199.508 21.119 1.00 17.22 ? 546 CYS A SG 1 ATOM 3722 H H . CYS A 1 240 ? 13.631 202.512 18.269 1.00 20.46 ? 546 CYS A H 1 ATOM 3723 H HA . CYS A 1 240 ? 11.674 201.802 19.721 1.00 19.21 ? 546 CYS A HA 1 ATOM 3724 H HB2 . CYS A 1 240 ? 13.282 200.274 18.972 1.00 18.22 ? 546 CYS A HB2 1 ATOM 3725 H HB3 . CYS A 1 240 ? 14.339 200.887 19.988 1.00 18.22 ? 546 CYS A HB3 1 ATOM 3726 N N . ALA A 1 241 ? 11.663 202.687 21.992 1.00 17.78 ? 547 ALA A N 1 ATOM 3727 C CA . ALA A 1 241 ? 11.701 203.301 23.322 1.00 17.09 ? 547 ALA A CA 1 ATOM 3728 C C . ALA A 1 241 ? 12.559 202.514 24.309 1.00 16.73 ? 547 ALA A C 1 ATOM 3729 O O . ALA A 1 241 ? 13.021 203.084 25.300 1.00 15.46 ? 547 ALA A O 1 ATOM 3730 C CB . ALA A 1 241 ? 10.289 203.439 23.878 1.00 15.69 ? 547 ALA A CB 1 ATOM 3731 H H . ALA A 1 241 ? 10.898 202.366 21.766 1.00 21.34 ? 547 ALA A H 1 ATOM 3732 H HA . ALA A 1 241 ? 12.078 204.192 23.245 1.00 20.51 ? 547 ALA A HA 1 ATOM 3733 H HB1 . ALA A 1 241 ? 10.334 203.846 24.757 1.00 18.83 ? 547 ALA A HB1 1 ATOM 3734 H HB2 . ALA A 1 241 ? 9.768 203.997 23.280 1.00 18.83 ? 547 ALA A HB2 1 ATOM 3735 H HB3 . ALA A 1 241 ? 9.888 202.558 23.941 1.00 18.83 ? 547 ALA A HB3 1 ATOM 3736 N N . GLY A 1 242 ? 12.778 201.232 24.072 1.00 19.93 ? 548 GLY A N 1 ATOM 3737 C CA . GLY A 1 242 ? 13.566 200.415 24.976 1.00 16.14 ? 548 GLY A CA 1 ATOM 3738 C C . GLY A 1 242 ? 13.189 198.948 24.949 1.00 17.18 ? 548 GLY A C 1 ATOM 3739 O O . GLY A 1 242 ? 12.044 198.553 24.755 1.00 17.48 ? 548 GLY A O 1 ATOM 3740 H H . GLY A 1 242 ? 12.478 200.808 23.387 1.00 23.92 ? 548 GLY A H 1 ATOM 3741 H HA2 . GLY A 1 242 ? 14.504 200.492 24.741 1.00 19.36 ? 548 GLY A HA2 1 ATOM 3742 H HA3 . GLY A 1 242 ? 13.452 200.741 25.882 1.00 19.36 ? 548 GLY A HA3 1 ATOM 3743 N N . PHE A 1 243 ? 14.194 198.109 25.137 1.00 15.46 ? 549 PHE A N 1 ATOM 3744 C CA . PHE A 1 243 ? 13.958 196.710 25.454 1.00 19.20 ? 549 PHE A CA 1 ATOM 3745 C C . PHE A 1 243 ? 13.276 196.587 26.810 1.00 17.29 ? 549 PHE A C 1 ATOM 3746 O O . PHE A 1 243 ? 13.647 197.266 27.766 1.00 15.58 ? 549 PHE A O 1 ATOM 3747 C CB . PHE A 1 243 ? 15.278 195.942 25.503 1.00 15.05 ? 549 PHE A CB 1 ATOM 3748 C CG . PHE A 1 243 ? 16.041 195.942 24.230 1.00 15.09 ? 549 PHE A CG 1 ATOM 3749 C CD1 . PHE A 1 243 ? 15.398 195.964 23.007 1.00 18.81 ? 549 PHE A CD1 1 ATOM 3750 C CD2 . PHE A 1 243 ? 17.415 195.881 24.254 1.00 16.85 ? 549 PHE A CD2 1 ATOM 3751 C CE1 . PHE A 1 243 ? 16.126 195.948 21.822 1.00 19.20 ? 549 PHE A CE1 1 ATOM 3752 C CE2 . PHE A 1 243 ? 18.144 195.858 23.074 1.00 23.05 ? 549 PHE A CE2 1 ATOM 3753 C CZ . PHE A 1 243 ? 17.501 195.887 21.862 1.00 18.06 ? 549 PHE A CZ 1 ATOM 3754 H H . PHE A 1 243 ? 15.025 198.325 25.086 1.00 18.56 ? 549 PHE A H 1 ATOM 3755 H HA . PHE A 1 243 ? 13.388 196.310 24.779 1.00 23.05 ? 549 PHE A HA 1 ATOM 3756 H HB2 . PHE A 1 243 ? 15.842 196.340 26.184 1.00 18.06 ? 549 PHE A HB2 1 ATOM 3757 H HB3 . PHE A 1 243 ? 15.090 195.019 25.733 1.00 18.06 ? 549 PHE A HB3 1 ATOM 3758 H HD1 . PHE A 1 243 ? 14.469 196.001 22.976 1.00 22.57 ? 549 PHE A HD1 1 ATOM 3759 H HD2 . PHE A 1 243 ? 17.861 195.856 25.070 1.00 20.22 ? 549 PHE A HD2 1 ATOM 3760 H HE1 . PHE A 1 243 ? 15.685 195.968 21.004 1.00 23.04 ? 549 PHE A HE1 1 ATOM 3761 H HE2 . PHE A 1 243 ? 19.073 195.823 23.104 1.00 27.66 ? 549 PHE A HE2 1 ATOM 3762 H HZ . PHE A 1 243 ? 17.991 195.879 21.072 1.00 21.67 ? 549 PHE A HZ 1 ATOM 3763 N N . GLY A 1 244 ? 12.296 195.691 26.902 1.00 20.38 ? 550 GLY A N 1 ATOM 3764 C CA . GLY A 1 244 ? 11.783 195.311 28.205 1.00 20.03 ? 550 GLY A CA 1 ATOM 3765 C C . GLY A 1 244 ? 12.862 194.649 29.041 1.00 17.60 ? 550 GLY A C 1 ATOM 3766 O O . GLY A 1 244 ? 13.746 193.966 28.523 1.00 16.07 ? 550 GLY A O 1 ATOM 3767 H H . GLY A 1 244 ? 11.921 195.297 26.236 1.00 24.46 ? 550 GLY A H 1 ATOM 3768 H HA2 . GLY A 1 244 ? 11.463 196.098 28.674 1.00 24.04 ? 550 GLY A HA2 1 ATOM 3769 H HA3 . GLY A 1 244 ? 11.045 194.690 28.099 1.00 24.04 ? 550 GLY A HA3 1 ATOM 3770 N N . VAL A 1 245 ? 12.822 194.887 30.349 1.00 16.88 ? 551 VAL A N 1 ATOM 3771 C CA A VAL A 1 245 ? 13.806 194.330 31.269 0.38 20.60 ? 551 VAL A CA 1 ATOM 3772 C CA B VAL A 1 245 ? 13.807 194.330 31.272 0.62 21.01 ? 551 VAL A CA 1 ATOM 3773 C C . VAL A 1 245 ? 13.111 193.375 32.228 1.00 17.67 ? 551 VAL A C 1 ATOM 3774 O O . VAL A 1 245 ? 12.102 193.728 32.848 1.00 14.42 ? 551 VAL A O 1 ATOM 3775 C CB A VAL A 1 245 ? 14.544 195.431 32.047 0.38 21.38 ? 551 VAL A CB 1 ATOM 3776 C CB B VAL A 1 245 ? 14.563 195.419 32.058 0.62 21.66 ? 551 VAL A CB 1 ATOM 3777 C CG1 A VAL A 1 245 ? 15.740 194.854 32.763 0.38 18.55 ? 551 VAL A CG1 1 ATOM 3778 C CG1 B VAL A 1 245 ? 15.239 196.343 31.091 0.62 24.66 ? 551 VAL A CG1 1 ATOM 3779 C CG2 A VAL A 1 245 ? 14.981 196.523 31.099 0.38 23.96 ? 551 VAL A CG2 1 ATOM 3780 C CG2 B VAL A 1 245 ? 13.642 196.196 32.991 0.62 18.19 ? 551 VAL A CG2 1 ATOM 3781 H H A VAL A 1 245 ? 12.225 195.374 30.733 0.38 20.26 ? 551 VAL A H 1 ATOM 3782 H H B VAL A 1 245 ? 12.225 195.374 30.732 0.62 20.26 ? 551 VAL A H 1 ATOM 3783 H HA A VAL A 1 245 ? 14.463 193.826 30.764 0.38 24.73 ? 551 VAL A HA 1 ATOM 3784 H HA B VAL A 1 245 ? 14.460 193.822 30.766 0.62 25.21 ? 551 VAL A HA 1 ATOM 3785 H HB A VAL A 1 245 ? 13.947 195.817 32.706 0.38 25.66 ? 551 VAL A HB 1 ATOM 3786 H HB B VAL A 1 245 ? 15.249 194.998 32.599 0.62 25.99 ? 551 VAL A HB 1 ATOM 3787 H HG11 A VAL A 1 245 ? 16.191 195.564 33.246 0.38 22.26 ? 551 VAL A HG11 1 ATOM 3788 H HG11 B VAL A 1 245 ? 15.714 197.027 31.588 0.62 29.59 ? 551 VAL A HG11 1 ATOM 3789 H HG12 A VAL A 1 245 ? 15.437 194.171 33.382 0.38 22.26 ? 551 VAL A HG12 1 ATOM 3790 H HG12 B VAL A 1 245 ? 15.863 195.832 30.552 0.62 29.59 ? 551 VAL A HG12 1 ATOM 3791 H HG13 A VAL A 1 245 ? 16.341 194.464 32.109 0.38 22.26 ? 551 VAL A HG13 1 ATOM 3792 H HG13 B VAL A 1 245 ? 14.567 196.751 30.523 0.62 29.59 ? 551 VAL A HG13 1 ATOM 3793 H HG21 A VAL A 1 245 ? 15.445 197.210 31.602 0.38 28.75 ? 551 VAL A HG21 1 ATOM 3794 H HG21 B VAL A 1 245 ? 14.162 196.867 33.461 0.62 21.83 ? 551 VAL A HG21 1 ATOM 3795 H HG22 A VAL A 1 245 ? 15.574 196.143 30.432 0.38 28.75 ? 551 VAL A HG22 1 ATOM 3796 H HG22 B VAL A 1 245 ? 12.948 196.623 32.465 0.62 21.83 ? 551 VAL A HG22 1 ATOM 3797 H HG23 A VAL A 1 245 ? 14.197 196.900 30.669 0.38 28.75 ? 551 VAL A HG23 1 ATOM 3798 H HG23 B VAL A 1 245 ? 13.244 195.580 33.626 0.62 21.83 ? 551 VAL A HG23 1 ATOM 3799 N N . ASP A 1 246 ? 13.653 192.172 32.346 1.00 16.13 ? 552 ASP A N 1 ATOM 3800 C CA . ASP A 1 246 ? 13.215 191.250 33.385 1.00 17.63 ? 552 ASP A CA 1 ATOM 3801 C C . ASP A 1 246 ? 13.629 191.824 34.735 1.00 16.76 ? 552 ASP A C 1 ATOM 3802 O O . ASP A 1 246 ? 14.813 191.829 35.075 1.00 17.50 ? 552 ASP A O 1 ATOM 3803 C CB . ASP A 1 246 ? 13.842 189.882 33.160 1.00 22.10 ? 552 ASP A CB 1 ATOM 3804 C CG . ASP A 1 246 ? 13.441 188.865 34.220 1.00 22.71 ? 552 ASP A CG 1 ATOM 3805 O OD1 . ASP A 1 246 ? 12.755 189.230 35.204 1.00 20.45 ? 552 ASP A OD1 1 ATOM 3806 O OD2 . ASP A 1 246 ? 13.840 187.697 34.054 1.00 23.49 ? 552 ASP A OD2 1 ATOM 3807 H H . ASP A 1 246 ? 14.275 191.864 31.839 1.00 19.36 ? 552 ASP A H 1 ATOM 3808 H HA . ASP A 1 246 ? 12.249 191.162 33.364 1.00 21.15 ? 552 ASP A HA 1 ATOM 3809 H HB2 . ASP A 1 246 ? 13.557 189.543 32.297 1.00 26.52 ? 552 ASP A HB2 1 ATOM 3810 H HB3 . ASP A 1 246 ? 14.807 189.970 33.180 1.00 26.52 ? 552 ASP A HB3 1 ATOM 3811 N N . GLU A 1 247 ? 12.669 192.333 35.504 1.00 18.69 ? 553 GLU A N 1 ATOM 3812 C CA . GLU A 1 247 ? 13.026 193.023 36.736 1.00 18.02 ? 553 GLU A CA 1 ATOM 3813 C C . GLU A 1 247 ? 13.595 192.079 37.798 1.00 21.72 ? 553 GLU A C 1 ATOM 3814 O O . GLU A 1 247 ? 14.265 192.558 38.722 1.00 18.05 ? 553 GLU A O 1 ATOM 3815 C CB . GLU A 1 247 ? 11.813 193.775 37.263 1.00 16.66 ? 553 GLU A CB 1 ATOM 3816 C CG . GLU A 1 247 ? 11.466 195.017 36.437 1.00 19.04 ? 553 GLU A CG 1 ATOM 3817 C CD . GLU A 1 247 ? 10.170 195.685 36.867 1.00 26.41 ? 553 GLU A CD 1 ATOM 3818 O OE1 . GLU A 1 247 ? 9.455 195.108 37.720 1.00 24.07 ? 553 GLU A OE1 1 ATOM 3819 O OE2 . GLU A 1 247 ? 9.862 196.789 36.346 1.00 27.17 ? 553 GLU A OE2 1 ATOM 3820 H H . GLU A 1 247 ? 11.825 192.293 35.340 1.00 22.43 ? 553 GLU A H 1 ATOM 3821 H HA . GLU A 1 247 ? 13.711 193.679 36.533 1.00 21.62 ? 553 GLU A HA 1 ATOM 3822 H HB2 . GLU A 1 247 ? 11.045 193.183 37.249 1.00 19.99 ? 553 GLU A HB2 1 ATOM 3823 H HB3 . GLU A 1 247 ? 11.993 194.062 38.172 1.00 19.99 ? 553 GLU A HB3 1 ATOM 3824 H HG2 . GLU A 1 247 ? 12.181 195.666 36.530 1.00 22.85 ? 553 GLU A HG2 1 ATOM 3825 H HG3 . GLU A 1 247 ? 11.374 194.759 35.506 1.00 22.85 ? 553 GLU A HG3 1 ATOM 3826 N N . GLU A 1 248 ? 13.368 190.753 37.676 1.00 20.74 ? 554 GLU A N 1 ATOM 3827 C CA . GLU A 1 248 ? 14.014 189.767 38.552 1.00 20.72 ? 554 GLU A CA 1 ATOM 3828 C C . GLU A 1 248 ? 15.511 189.648 38.301 1.00 14.98 ? 554 GLU A C 1 ATOM 3829 O O . GLU A 1 248 ? 16.192 188.934 39.039 1.00 20.11 ? 554 GLU A O 1 ATOM 3830 C CB . GLU A 1 248 ? 13.368 188.381 38.388 1.00 19.05 ? 554 GLU A CB 1 ATOM 3831 C CG . GLU A 1 248 ? 11.913 188.337 38.815 1.00 27.71 ? 554 GLU A CG 1 ATOM 3832 C CD . GLU A 1 248 ? 11.713 188.516 40.328 1.00 32.60 ? 554 GLU A CD 1 ATOM 3833 O OE1 . GLU A 1 248 ? 12.480 187.929 41.121 1.00 39.31 ? 554 GLU A OE1 1 ATOM 3834 O OE2 . GLU A 1 248 ? 10.778 189.230 40.732 1.00 30.00 ? 554 GLU A OE2 1 ATOM 3835 H H . GLU A 1 248 ? 12.843 190.405 37.091 1.00 24.89 ? 554 GLU A H 1 ATOM 3836 H HA . GLU A 1 248 ? 13.891 190.043 39.473 1.00 24.87 ? 554 GLU A HA 1 ATOM 3837 H HB2 . GLU A 1 248 ? 13.412 188.124 37.454 1.00 22.86 ? 554 GLU A HB2 1 ATOM 3838 H HB3 . GLU A 1 248 ? 13.856 187.742 38.930 1.00 22.86 ? 554 GLU A HB3 1 ATOM 3839 H HG2 . GLU A 1 248 ? 11.432 189.050 38.365 1.00 33.25 ? 554 GLU A HG2 1 ATOM 3840 H HG3 . GLU A 1 248 ? 11.538 187.478 38.565 1.00 33.25 ? 554 GLU A HG3 1 ATOM 3841 N N . LYS A 1 249 ? 16.039 190.325 37.289 1.00 18.32 ? 555 LYS A N 1 ATOM 3842 C CA . LYS A 1 249 ? 17.473 190.349 37.033 1.00 18.70 ? 555 LYS A CA 1 ATOM 3843 C C . LYS A 1 249 ? 18.053 191.748 37.193 1.00 17.85 ? 555 LYS A C 1 ATOM 3844 O O . LYS A 1 249 ? 19.135 192.035 36.673 1.00 19.54 ? 555 LYS A O 1 ATOM 3845 C CB . LYS A 1 249 ? 17.762 189.783 35.644 1.00 22.37 ? 555 LYS A CB 1 ATOM 3846 C CG . LYS A 1 249 ? 17.411 188.315 35.565 1.00 19.65 ? 555 LYS A CG 1 ATOM 3847 C CD . LYS A 1 249 ? 17.677 187.733 34.216 1.00 33.12 ? 555 LYS A CD 1 ATOM 3848 C CE . LYS A 1 249 ? 17.529 186.215 34.239 1.00 29.62 ? 555 LYS A CE 1 ATOM 3849 N NZ . LYS A 1 249 ? 18.058 185.665 32.964 1.00 56.28 ? 555 LYS A NZ 1 ATOM 3850 H H . LYS A 1 249 ? 15.580 190.786 36.727 1.00 21.98 ? 555 LYS A H 1 ATOM 3851 H HA . LYS A 1 249 ? 17.912 189.775 37.680 1.00 22.44 ? 555 LYS A HA 1 ATOM 3852 H HB2 . LYS A 1 249 ? 17.231 190.260 34.987 1.00 26.84 ? 555 LYS A HB2 1 ATOM 3853 H HB3 . LYS A 1 249 ? 18.707 189.882 35.448 1.00 26.84 ? 555 LYS A HB3 1 ATOM 3854 H HG2 . LYS A 1 249 ? 17.943 187.827 36.213 1.00 23.59 ? 555 LYS A HG2 1 ATOM 3855 H HG3 . LYS A 1 249 ? 16.467 188.205 35.759 1.00 23.59 ? 555 LYS A HG3 1 ATOM 3856 H HD2 . LYS A 1 249 ? 17.041 188.093 33.579 1.00 39.75 ? 555 LYS A HD2 1 ATOM 3857 H HD3 . LYS A 1 249 ? 18.584 187.948 33.946 1.00 39.75 ? 555 LYS A HD3 1 ATOM 3858 H HE2 . LYS A 1 249 ? 18.041 185.846 34.976 1.00 35.55 ? 555 LYS A HE2 1 ATOM 3859 H HE3 . LYS A 1 249 ? 16.592 185.978 34.317 1.00 35.55 ? 555 LYS A HE3 1 ATOM 3860 H HZ1 . LYS A 1 249 ? 17.980 184.779 32.959 1.00 67.53 ? 555 LYS A HZ1 1 ATOM 3861 H HZ2 . LYS A 1 249 ? 17.603 185.999 32.276 1.00 67.53 ? 555 LYS A HZ2 1 ATOM 3862 H HZ3 . LYS A 1 249 ? 18.917 185.880 32.873 1.00 67.53 ? 555 LYS A HZ3 1 ATOM 3863 N N . CYS A 1 250 ? 17.363 192.618 37.924 1.00 20.25 ? 556 CYS A N 1 ATOM 3864 C CA . CYS A 1 250 ? 17.888 193.929 38.276 1.00 24.98 ? 556 CYS A CA 1 ATOM 3865 C C . CYS A 1 250 ? 18.079 193.998 39.784 1.00 25.13 ? 556 CYS A C 1 ATOM 3866 O O . CYS A 1 250 ? 17.141 193.745 40.548 1.00 22.57 ? 556 CYS A O 1 ATOM 3867 C CB . CYS A 1 250 ? 16.954 195.042 37.794 1.00 22.97 ? 556 CYS A CB 1 ATOM 3868 S SG . CYS A 1 250 ? 16.582 194.932 36.017 1.00 17.40 ? 556 CYS A SG 1 ATOM 3869 H H . CYS A 1 250 ? 16.575 192.468 38.233 1.00 24.30 ? 556 CYS A H 1 ATOM 3870 H HA . CYS A 1 250 ? 18.752 194.052 37.853 1.00 29.98 ? 556 CYS A HA 1 ATOM 3871 H HB2 . CYS A 1 250 ? 16.117 194.983 38.280 1.00 27.57 ? 556 CYS A HB2 1 ATOM 3872 H HB3 . CYS A 1 250 ? 17.374 195.900 37.960 1.00 27.57 ? 556 CYS A HB3 1 ATOM 3873 N N . GLY A 1 251 ? 19.279 194.379 40.199 1.00 20.06 ? 557 GLY A N 1 ATOM 3874 C CA . GLY A 1 251 ? 19.655 194.297 41.588 1.00 31.02 ? 557 GLY A CA 1 ATOM 3875 C C . GLY A 1 251 ? 20.337 192.981 41.866 1.00 27.97 ? 557 GLY A C 1 ATOM 3876 O O . GLY A 1 251 ? 20.588 192.160 40.979 1.00 29.94 ? 557 GLY A O 1 ATOM 3877 H H . GLY A 1 251 ? 19.895 194.691 39.686 1.00 24.07 ? 557 GLY A H 1 ATOM 3878 H HA2 . GLY A 1 251 ? 20.263 195.020 41.809 1.00 37.23 ? 557 GLY A HA2 1 ATOM 3879 H HA3 . GLY A 1 251 ? 18.866 194.368 42.148 1.00 37.23 ? 557 GLY A HA3 1 ATOM 3880 N N . VAL A 1 252 ? 20.651 192.776 43.134 1.00 26.65 ? 558 VAL A N 1 ATOM 3881 C CA . VAL A 1 252 ? 21.253 191.526 43.575 1.00 23.69 ? 558 VAL A CA 1 ATOM 3882 C C . VAL A 1 252 ? 20.462 191.013 44.764 1.00 25.03 ? 558 VAL A C 1 ATOM 3883 O O . VAL A 1 252 ? 19.833 191.785 45.498 1.00 21.28 ? 558 VAL A O 1 ATOM 3884 C CB . VAL A 1 252 ? 22.739 191.694 43.937 1.00 30.65 ? 558 VAL A CB 1 ATOM 3885 C CG1 . VAL A 1 252 ? 23.527 192.123 42.706 1.00 39.84 ? 558 VAL A CG1 1 ATOM 3886 C CG2 . VAL A 1 252 ? 22.904 192.717 45.040 1.00 28.06 ? 558 VAL A CG2 1 ATOM 3887 H H . VAL A 1 252 ? 20.525 193.347 43.765 1.00 31.98 ? 558 VAL A H 1 ATOM 3888 H HA . VAL A 1 252 ? 21.187 190.871 42.863 1.00 28.43 ? 558 VAL A HA 1 ATOM 3889 H HB . VAL A 1 252 ? 23.094 190.847 44.249 1.00 36.78 ? 558 VAL A HB 1 ATOM 3890 H HG11 . VAL A 1 252 ? 24.461 192.225 42.949 1.00 47.80 ? 558 VAL A HG11 1 ATOM 3891 H HG12 . VAL A 1 252 ? 23.435 191.444 42.020 1.00 47.80 ? 558 VAL A HG12 1 ATOM 3892 H HG13 . VAL A 1 252 ? 23.174 192.968 42.385 1.00 47.80 ? 558 VAL A HG13 1 ATOM 3893 H HG21 . VAL A 1 252 ? 23.847 192.806 45.250 1.00 33.67 ? 558 VAL A HG21 1 ATOM 3894 H HG22 . VAL A 1 252 ? 22.551 193.568 44.735 1.00 33.67 ? 558 VAL A HG22 1 ATOM 3895 H HG23 . VAL A 1 252 ? 22.416 192.418 45.823 1.00 33.67 ? 558 VAL A HG23 1 ATOM 3896 N N . LEU A 1 253 ? 20.485 189.695 44.939 1.00 27.78 ? 559 LEU A N 1 ATOM 3897 C CA . LEU A 1 253 ? 19.852 189.092 46.096 1.00 29.41 ? 559 LEU A CA 1 ATOM 3898 C C . LEU A 1 253 ? 20.512 189.598 47.369 1.00 25.96 ? 559 LEU A C 1 ATOM 3899 O O . LEU A 1 253 ? 21.732 189.529 47.516 1.00 29.01 ? 559 LEU A O 1 ATOM 3900 C CB . LEU A 1 253 ? 19.942 187.573 46.012 1.00 30.86 ? 559 LEU A CB 1 ATOM 3901 C CG . LEU A 1 253 ? 18.765 186.855 45.356 1.00 41.84 ? 559 LEU A CG 1 ATOM 3902 C CD1 . LEU A 1 253 ? 19.020 185.329 45.337 1.00 43.66 ? 559 LEU A CD1 1 ATOM 3903 C CD2 . LEU A 1 253 ? 17.456 187.148 46.080 1.00 34.45 ? 559 LEU A CD2 1 ATOM 3904 H H . LEU A 1 253 ? 20.859 189.135 44.405 1.00 33.34 ? 559 LEU A H 1 ATOM 3905 H HA . LEU A 1 253 ? 18.915 189.342 46.118 1.00 35.29 ? 559 LEU A HA 1 ATOM 3906 H HB2 . LEU A 1 253 ? 20.736 187.345 45.505 1.00 37.03 ? 559 LEU A HB2 1 ATOM 3907 H HB3 . LEU A 1 253 ? 20.025 187.224 46.914 1.00 37.03 ? 559 LEU A HB3 1 ATOM 3908 H HG . LEU A 1 253 ? 18.678 187.159 44.439 1.00 50.20 ? 559 LEU A HG 1 ATOM 3909 H HD11 . LEU A 1 253 ? 18.265 184.888 44.918 1.00 52.39 ? 559 LEU A HD11 1 ATOM 3910 H HD12 . LEU A 1 253 ? 19.830 185.151 44.832 1.00 52.39 ? 559 LEU A HD12 1 ATOM 3911 H HD13 . LEU A 1 253 ? 19.123 185.015 46.249 1.00 52.39 ? 559 LEU A HD13 1 ATOM 3912 H HD21 . LEU A 1 253 ? 16.736 186.675 45.633 1.00 41.34 ? 559 LEU A HD21 1 ATOM 3913 H HD22 . LEU A 1 253 ? 17.530 186.848 46.999 1.00 41.34 ? 559 LEU A HD22 1 ATOM 3914 H HD23 . LEU A 1 253 ? 17.289 188.103 46.055 1.00 41.34 ? 559 LEU A HD23 1 ATOM 3915 N N . ASP A 1 254 ? 19.695 190.133 48.276 1.00 24.84 ? 560 ASP A N 1 ATOM 3916 C CA . ASP A 1 254 ? 20.147 190.750 49.523 1.00 31.52 ? 560 ASP A CA 1 ATOM 3917 C C . ASP A 1 254 ? 20.977 192.015 49.281 1.00 27.56 ? 560 ASP A C 1 ATOM 3918 O O . ASP A 1 254 ? 21.752 192.433 50.151 1.00 28.00 ? 560 ASP A O 1 ATOM 3919 C CB . ASP A 1 254 ? 20.933 189.748 50.388 1.00 25.99 ? 560 ASP A CB 1 ATOM 3920 C CG . ASP A 1 254 ? 20.071 188.596 50.881 1.00 36.37 ? 560 ASP A CG 1 ATOM 3921 O OD1 . ASP A 1 254 ? 18.916 188.837 51.304 1.00 35.99 ? 560 ASP A OD1 1 ATOM 3922 O OD2 . ASP A 1 254 ? 20.550 187.439 50.840 1.00 45.87 ? 560 ASP A OD2 1 ATOM 3923 H H . ASP A 1 254 ? 18.840 190.150 48.185 1.00 29.80 ? 560 ASP A H 1 ATOM 3924 H HA . ASP A 1 254 ? 19.363 191.014 50.031 1.00 37.83 ? 560 ASP A HA 1 ATOM 3925 H HB2 . ASP A 1 254 ? 21.658 189.377 49.861 1.00 31.19 ? 560 ASP A HB2 1 ATOM 3926 H HB3 . ASP A 1 254 ? 21.288 190.210 51.163 1.00 31.19 ? 560 ASP A HB3 1 ATOM 3927 N N . GLY A 1 255 ? 20.828 192.643 48.117 1.00 25.60 ? 561 GLY A N 1 ATOM 3928 C CA . GLY A 1 255 ? 21.494 193.915 47.876 1.00 24.88 ? 561 GLY A CA 1 ATOM 3929 C C . GLY A 1 255 ? 20.915 194.995 48.767 1.00 25.37 ? 561 GLY A C 1 ATOM 3930 O O . GLY A 1 255 ? 19.691 195.134 48.883 1.00 28.41 ? 561 GLY A O 1 ATOM 3931 H H . GLY A 1 255 ? 20.352 192.357 47.460 1.00 30.72 ? 561 GLY A H 1 ATOM 3932 H HA2 . GLY A 1 255 ? 22.443 193.831 48.061 1.00 29.85 ? 561 GLY A HA2 1 ATOM 3933 H HA3 . GLY A 1 255 ? 21.378 194.177 46.949 1.00 29.85 ? 561 GLY A HA3 1 ATOM 3934 N N . SER A 1 256 ? 21.786 195.764 49.400 1.00 25.31 ? 562 SER A N 1 ATOM 3935 C CA . SER A 1 256 ? 21.359 196.819 50.304 1.00 26.10 ? 562 SER A CA 1 ATOM 3936 C C . SER A 1 256 ? 21.463 198.175 49.619 1.00 24.49 ? 562 SER A C 1 ATOM 3937 O O . SER A 1 256 ? 21.656 198.278 48.406 1.00 23.20 ? 562 SER A O 1 ATOM 3938 C CB . SER A 1 256 ? 22.197 196.772 51.586 1.00 36.25 ? 562 SER A CB 1 ATOM 3939 O OG . SER A 1 256 ? 23.570 196.960 51.276 1.00 43.95 ? 562 SER A OG 1 ATOM 3940 H H . SER A 1 256 ? 22.640 195.695 49.323 1.00 30.37 ? 562 SER A H 1 ATOM 3941 H HA . SER A 1 256 ? 20.430 196.674 50.545 1.00 31.32 ? 562 SER A HA 1 ATOM 3942 H HB2 . SER A 1 256 ? 21.905 197.478 52.183 1.00 43.49 ? 562 SER A HB2 1 ATOM 3943 H HB3 . SER A 1 256 ? 22.082 195.907 52.009 1.00 43.49 ? 562 SER A HB3 1 ATOM 3944 H HG . SER A 1 256 ? 23.681 197.706 50.905 1.00 52.74 ? 562 SER A HG 1 ATOM 3945 N N . TYR A 1 257 ? 21.324 199.243 50.402 1.00 25.71 ? 563 TYR A N 1 ATOM 3946 C CA . TYR A 1 257 ? 21.345 200.570 49.808 1.00 23.81 ? 563 TYR A CA 1 ATOM 3947 C C . TYR A 1 257 ? 22.737 200.980 49.340 1.00 24.24 ? 563 TYR A C 1 ATOM 3948 O O . TYR A 1 257 ? 22.857 202.035 48.709 1.00 25.15 ? 563 TYR A O 1 ATOM 3949 C CB . TYR A 1 257 ? 20.755 201.582 50.800 1.00 22.24 ? 563 TYR A CB 1 ATOM 3950 C CG . TYR A 1 257 ? 19.308 201.269 51.107 1.00 24.30 ? 563 TYR A CG 1 ATOM 3951 C CD1 . TYR A 1 257 ? 18.294 201.796 50.325 1.00 16.35 ? 563 TYR A CD1 1 ATOM 3952 C CD2 . TYR A 1 257 ? 18.953 200.406 52.150 1.00 24.82 ? 563 TYR A CD2 1 ATOM 3953 C CE1 . TYR A 1 257 ? 16.966 201.502 50.576 1.00 17.16 ? 563 TYR A CE1 1 ATOM 3954 C CE2 . TYR A 1 257 ? 17.619 200.105 52.411 1.00 19.52 ? 563 TYR A CE2 1 ATOM 3955 C CZ . TYR A 1 257 ? 16.633 200.656 51.618 1.00 18.51 ? 563 TYR A CZ 1 ATOM 3956 O OH . TYR A 1 257 ? 15.313 200.367 51.857 1.00 17.11 ? 563 TYR A OH 1 ATOM 3957 H H . TYR A 1 257 ? 21.219 199.226 51.256 1.00 30.86 ? 563 TYR A H 1 ATOM 3958 H HA . TYR A 1 257 ? 20.770 200.563 49.026 1.00 28.58 ? 563 TYR A HA 1 ATOM 3959 H HB2 . TYR A 1 257 ? 21.256 201.548 51.630 1.00 26.68 ? 563 TYR A HB2 1 ATOM 3960 H HB3 . TYR A 1 257 ? 20.800 202.472 50.417 1.00 26.68 ? 563 TYR A HB3 1 ATOM 3961 H HD1 . TYR A 1 257 ? 18.510 202.365 49.621 1.00 19.62 ? 563 TYR A HD1 1 ATOM 3962 H HD2 . TYR A 1 257 ? 19.619 200.035 52.683 1.00 29.79 ? 563 TYR A HD2 1 ATOM 3963 H HE1 . TYR A 1 257 ? 16.299 201.871 50.044 1.00 20.59 ? 563 TYR A HE1 1 ATOM 3964 H HE2 . TYR A 1 257 ? 17.395 199.536 53.111 1.00 23.43 ? 563 TYR A HE2 1 ATOM 3965 H HH . TYR A 1 257 ? 15.247 199.845 52.513 1.00 20.53 ? 563 TYR A HH 1 ATOM 3966 N N . ASN A 1 258 ? 23.769 200.169 49.590 1.00 22.22 ? 564 ASN A N 1 ATOM 3967 C CA A ASN A 1 258 ? 25.109 200.494 49.118 0.54 27.25 ? 564 ASN A CA 1 ATOM 3968 C CA B ASN A 1 258 ? 25.133 200.428 49.145 0.46 27.26 ? 564 ASN A CA 1 ATOM 3969 C C . ASN A 1 258 ? 25.395 199.958 47.719 1.00 25.20 ? 564 ASN A C 1 ATOM 3970 O O . ASN A 1 258 ? 26.511 200.129 47.224 1.00 27.67 ? 564 ASN A O 1 ATOM 3971 C CB A ASN A 1 258 ? 26.167 199.962 50.087 0.54 25.82 ? 564 ASN A CB 1 ATOM 3972 C CB B ASN A 1 258 ? 26.134 199.738 50.078 0.46 25.65 ? 564 ASN A CB 1 ATOM 3973 C CG A ASN A 1 258 ? 26.166 198.466 50.178 0.54 25.21 ? 564 ASN A CG 1 ATOM 3974 C CG B ASN A 1 258 ? 27.535 200.312 49.958 0.46 27.49 ? 564 ASN A CG 1 ATOM 3975 O OD1 A ASN A 1 258 ? 25.108 197.835 50.158 0.54 29.53 ? 564 ASN A OD1 1 ATOM 3976 O OD1 B ASN A 1 258 ? 27.708 201.505 49.712 0.46 30.27 ? 564 ASN A OD1 1 ATOM 3977 N ND2 A ASN A 1 258 ? 27.354 197.878 50.278 0.54 30.99 ? 564 ASN A ND2 1 ATOM 3978 N ND2 B ASN A 1 258 ? 28.543 199.467 50.140 0.46 26.91 ? 564 ASN A ND2 1 ATOM 3979 H H A ASN A 1 258 ? 23.716 199.431 50.029 0.54 26.66 ? 564 ASN A H 1 ATOM 3980 H H B ASN A 1 258 ? 23.695 199.436 50.034 0.46 26.66 ? 564 ASN A H 1 ATOM 3981 H HA A ASN A 1 258 ? 25.199 201.459 49.086 0.54 32.70 ? 564 ASN A HA 1 ATOM 3982 H HA B ASN A 1 258 ? 25.299 201.383 49.180 0.46 32.72 ? 564 ASN A HA 1 ATOM 3983 H HB2 A ASN A 1 258 ? 27.044 200.243 49.783 0.54 30.98 ? 564 ASN A HB2 1 ATOM 3984 H HB2 B ASN A 1 258 ? 25.841 199.851 50.996 0.46 30.78 ? 564 ASN A HB2 1 ATOM 3985 H HB3 A ASN A 1 258 ? 25.992 200.317 50.973 0.54 30.98 ? 564 ASN A HB3 1 ATOM 3986 H HB3 B ASN A 1 258 ? 26.176 198.795 49.855 0.46 30.78 ? 564 ASN A HB3 1 ATOM 3987 H HD21 A ASN A 1 258 ? 27.406 197.021 50.333 0.54 37.19 ? 564 ASN A HD21 1 ATOM 3988 H HD21 B ASN A 1 258 ? 29.354 199.746 50.082 0.46 32.29 ? 564 ASN A HD21 1 ATOM 3989 H HD22 A ASN A 1 258 ? 28.070 198.354 50.287 0.54 37.19 ? 564 ASN A HD22 1 ATOM 3990 H HD22 B ASN A 1 258 ? 28.384 198.640 50.316 0.46 32.29 ? 564 ASN A HD22 1 ATOM 3991 N N . VAL A 1 259 ? 24.427 199.332 47.065 1.00 26.36 ? 565 VAL A N 1 ATOM 3992 C CA . VAL A 1 259 ? 24.584 198.877 45.688 1.00 29.51 ? 565 VAL A CA 1 ATOM 3993 C C . VAL A 1 259 ? 23.590 199.647 44.829 1.00 25.17 ? 565 VAL A C 1 ATOM 3994 O O . VAL A 1 259 ? 22.412 199.766 45.188 1.00 28.24 ? 565 VAL A O 1 ATOM 3995 C CB . VAL A 1 259 ? 24.385 197.352 45.560 1.00 29.95 ? 565 VAL A CB 1 ATOM 3996 C CG1 . VAL A 1 259 ? 23.077 196.936 46.133 1.00 31.03 ? 565 VAL A CG1 1 ATOM 3997 C CG2 . VAL A 1 259 ? 24.471 196.906 44.099 1.00 31.22 ? 565 VAL A CG2 1 ATOM 3998 H H . VAL A 1 259 ? 23.656 199.155 47.402 1.00 31.63 ? 565 VAL A H 1 ATOM 3999 H HA . VAL A 1 259 ? 25.479 199.091 45.381 1.00 35.41 ? 565 VAL A HA 1 ATOM 4000 H HB . VAL A 1 259 ? 25.087 196.899 46.053 1.00 35.95 ? 565 VAL A HB 1 ATOM 4001 H HG11 . VAL A 1 259 ? 22.982 195.975 46.038 1.00 37.23 ? 565 VAL A HG11 1 ATOM 4002 H HG12 . VAL A 1 259 ? 23.052 197.180 47.072 1.00 37.23 ? 565 VAL A HG12 1 ATOM 4003 H HG13 . VAL A 1 259 ? 22.365 197.388 45.655 1.00 37.23 ? 565 VAL A HG13 1 ATOM 4004 H HG21 . VAL A 1 259 ? 24.342 195.946 44.055 1.00 37.46 ? 565 VAL A HG21 1 ATOM 4005 H HG22 . VAL A 1 259 ? 23.779 197.357 43.591 1.00 37.46 ? 565 VAL A HG22 1 ATOM 4006 H HG23 . VAL A 1 259 ? 25.345 197.140 43.749 1.00 37.46 ? 565 VAL A HG23 1 ATOM 4007 N N . SER A 1 260 ? 24.071 200.197 43.720 1.00 24.80 ? 566 SER A N 1 ATOM 4008 C CA . SER A 1 260 ? 23.207 200.952 42.822 1.00 31.28 ? 566 SER A CA 1 ATOM 4009 C C . SER A 1 260 ? 22.435 200.001 41.916 1.00 23.15 ? 566 SER A C 1 ATOM 4010 O O . SER A 1 260 ? 22.945 198.951 41.516 1.00 20.45 ? 566 SER A O 1 ATOM 4011 C CB . SER A 1 260 ? 24.021 201.939 41.980 1.00 27.80 ? 566 SER A CB 1 ATOM 4012 O OG . SER A 1 260 ? 24.537 202.983 42.789 1.00 53.53 ? 566 SER A OG 1 ATOM 4013 H H . SER A 1 260 ? 24.890 200.147 43.465 1.00 29.76 ? 566 SER A H 1 ATOM 4014 H HA . SER A 1 260 ? 22.566 201.458 43.346 1.00 37.54 ? 566 SER A HA 1 ATOM 4015 H HB2 . SER A 1 260 ? 24.759 201.467 41.565 1.00 33.36 ? 566 SER A HB2 1 ATOM 4016 H HB3 . SER A 1 260 ? 23.447 202.322 41.299 1.00 33.36 ? 566 SER A HB3 1 ATOM 4017 H HG . SER A 1 260 ? 24.981 203.519 42.319 1.00 64.24 ? 566 SER A HG 1 ATOM 4018 N N . CYS A 1 261 ? 21.193 200.371 41.611 1.00 18.97 ? 567 CYS A N 1 ATOM 4019 C CA . CYS A 1 261 ? 20.309 199.504 40.845 1.00 27.31 ? 567 CYS A CA 1 ATOM 4020 C C . CYS A 1 261 ? 20.829 199.304 39.425 1.00 30.72 ? 567 CYS A C 1 ATOM 4021 O O . CYS A 1 261 ? 20.987 200.264 38.662 1.00 23.38 ? 567 CYS A O 1 ATOM 4022 C CB . CYS A 1 261 ? 18.903 200.086 40.803 1.00 24.95 ? 567 CYS A CB 1 ATOM 4023 S SG . CYS A 1 261 ? 17.797 199.074 39.736 1.00 15.25 ? 567 CYS A SG 1 ATOM 4024 H H . CYS A 1 261 ? 20.840 201.122 41.838 1.00 22.77 ? 567 CYS A H 1 ATOM 4025 H HA . CYS A 1 261 ? 20.263 198.636 41.275 1.00 32.78 ? 567 CYS A HA 1 ATOM 4026 H HB2 . CYS A 1 261 ? 18.534 200.099 41.700 1.00 29.94 ? 567 CYS A HB2 1 ATOM 4027 H HB3 . CYS A 1 261 ? 18.938 200.985 40.440 1.00 29.94 ? 567 CYS A HB3 1 ATOM 4028 N N . LEU A 1 262 ? 21.060 198.047 39.067 1.00 32.28 ? 568 LEU A N 1 ATOM 4029 C CA . LEU A 1 262 ? 21.710 197.726 37.809 1.00 27.58 ? 568 LEU A CA 1 ATOM 4030 C C . LEU A 1 262 ? 21.152 196.412 37.286 1.00 23.88 ? 568 LEU A C 1 ATOM 4031 O O . LEU A 1 262 ? 21.052 195.440 38.036 1.00 31.30 ? 568 LEU A O 1 ATOM 4032 C CB . LEU A 1 262 ? 23.222 197.636 38.014 1.00 32.78 ? 568 LEU A CB 1 ATOM 4033 C CG . LEU A 1 262 ? 24.124 197.634 36.786 1.00 47.71 ? 568 LEU A CG 1 ATOM 4034 C CD1 . LEU A 1 262 ? 25.304 198.565 37.029 1.00 56.68 ? 568 LEU A CD1 1 ATOM 4035 C CD2 . LEU A 1 262 ? 24.603 196.224 36.477 1.00 50.89 ? 568 LEU A CD2 1 ATOM 4036 H H . LEU A 1 262 ? 20.847 197.360 39.539 1.00 38.73 ? 568 LEU A H 1 ATOM 4037 H HA . LEU A 1 262 ? 21.526 198.422 37.159 1.00 33.10 ? 568 LEU A HA 1 ATOM 4038 H HB2 . LEU A 1 262 ? 23.493 198.392 38.559 1.00 39.33 ? 568 LEU A HB2 1 ATOM 4039 H HB3 . LEU A 1 262 ? 23.407 196.816 38.499 1.00 39.33 ? 568 LEU A HB3 1 ATOM 4040 H HG . LEU A 1 262 ? 23.627 197.963 36.020 1.00 57.25 ? 568 LEU A HG 1 ATOM 4041 H HD11 . LEU A 1 262 ? 25.875 198.562 36.245 1.00 68.01 ? 568 LEU A HD11 1 ATOM 4042 H HD12 . LEU A 1 262 ? 24.970 199.461 37.191 1.00 68.01 ? 568 LEU A HD12 1 ATOM 4043 H HD13 . LEU A 1 262 ? 25.799 198.251 37.802 1.00 68.01 ? 568 LEU A HD13 1 ATOM 4044 H HD21 . LEU A 1 262 ? 25.173 196.249 35.694 1.00 61.06 ? 568 LEU A HD21 1 ATOM 4045 H HD22 . LEU A 1 262 ? 25.100 195.887 37.239 1.00 61.06 ? 568 LEU A HD22 1 ATOM 4046 H HD23 . LEU A 1 262 ? 23.832 195.660 36.308 1.00 61.06 ? 568 LEU A HD23 1 ATOM 4047 N N . CYS A 1 263 ? 20.777 196.394 36.014 1.00 27.79 ? 569 CYS A N 1 ATOM 4048 C CA . CYS A 1 263 ? 20.298 195.192 35.351 1.00 25.79 ? 569 CYS A CA 1 ATOM 4049 C C . CYS A 1 263 ? 21.437 194.521 34.589 1.00 21.49 ? 569 CYS A C 1 ATOM 4050 O O . CYS A 1 263 ? 22.213 195.182 33.900 1.00 21.52 ? 569 CYS A O 1 ATOM 4051 C CB . CYS A 1 263 ? 19.154 195.528 34.394 1.00 22.95 ? 569 CYS A CB 1 ATOM 4052 S SG . CYS A 1 263 ? 17.755 196.404 35.154 1.00 19.48 ? 569 CYS A SG 1 ATOM 4053 H H . CYS A 1 263 ? 20.793 197.085 35.501 1.00 33.34 ? 569 CYS A H 1 ATOM 4054 H HA . CYS A 1 263 ? 19.966 194.569 36.016 1.00 30.95 ? 569 CYS A HA 1 ATOM 4055 H HB2 . CYS A 1 263 ? 19.501 196.090 33.684 1.00 27.54 ? 569 CYS A HB2 1 ATOM 4056 H HB3 . CYS A 1 263 ? 18.813 194.701 34.019 1.00 27.54 ? 569 CYS A HB3 1 ATOM 4057 N N . SER A 1 264 ? 21.536 193.205 34.730 1.00 17.98 ? 570 SER A N 1 ATOM 4058 C CA . SER A 1 264 ? 22.512 192.427 33.982 1.00 30.76 ? 570 SER A CA 1 ATOM 4059 C C . SER A 1 264 ? 22.152 192.391 32.489 1.00 27.08 ? 570 SER A C 1 ATOM 4060 O O . SER A 1 264 ? 21.004 192.613 32.089 1.00 21.92 ? 570 SER A O 1 ATOM 4061 C CB . SER A 1 264 ? 22.581 191.008 34.539 1.00 28.66 ? 570 SER A CB 1 ATOM 4062 O OG . SER A 1 264 ? 21.326 190.367 34.405 1.00 28.74 ? 570 SER A OG 1 ATOM 4063 H H . SER A 1 264 ? 21.044 192.736 35.257 1.00 21.58 ? 570 SER A H 1 ATOM 4064 H HA . SER A 1 264 ? 23.387 192.835 34.075 1.00 36.91 ? 570 SER A HA 1 ATOM 4065 H HB2 . SER A 1 264 ? 23.249 190.505 34.046 1.00 34.39 ? 570 SER A HB2 1 ATOM 4066 H HB3 . SER A 1 264 ? 22.819 191.046 35.478 1.00 34.39 ? 570 SER A HB3 1 ATOM 4067 H HG . SER A 1 264 ? 21.108 190.329 33.594 1.00 34.48 ? 570 SER A HG 1 ATOM 4068 N N . THR A 1 265 ? 23.159 192.111 31.659 1.00 27.73 ? 571 THR A N 1 ATOM 4069 C CA . THR A 1 265 ? 22.965 192.193 30.211 1.00 34.89 ? 571 THR A CA 1 ATOM 4070 C C . THR A 1 265 ? 21.807 191.315 29.752 1.00 29.66 ? 571 THR A C 1 ATOM 4071 O O . THR A 1 265 ? 20.993 191.732 28.916 1.00 22.91 ? 571 THR A O 1 ATOM 4072 C CB . THR A 1 265 ? 24.249 191.799 29.473 1.00 40.24 ? 571 THR A CB 1 ATOM 4073 O OG1 . THR A 1 265 ? 24.854 190.674 30.118 1.00 50.15 ? 571 THR A OG1 1 ATOM 4074 C CG2 . THR A 1 265 ? 25.236 192.960 29.436 1.00 44.85 ? 571 THR A CG2 1 ATOM 4075 H H . THR A 1 265 ? 23.949 191.875 31.904 1.00 33.28 ? 571 THR A H 1 ATOM 4076 H HA . THR A 1 265 ? 22.755 193.110 29.974 1.00 41.86 ? 571 THR A HA 1 ATOM 4077 H HB . THR A 1 265 ? 24.029 191.561 28.559 1.00 48.29 ? 571 THR A HB 1 ATOM 4078 H HG1 . THR A 1 265 ? 25.043 190.866 30.914 1.00 60.18 ? 571 THR A HG1 1 ATOM 4079 H HG21 . THR A 1 265 ? 26.042 192.694 28.966 1.00 53.82 ? 571 THR A HG21 1 ATOM 4080 H HG22 . THR A 1 265 ? 24.839 193.718 28.978 1.00 53.82 ? 571 THR A HG22 1 ATOM 4081 H HG23 . THR A 1 265 ? 25.471 193.224 30.339 1.00 53.82 ? 571 THR A HG23 1 ATOM 4082 N N . ASP A 1 266 ? 21.696 190.111 30.306 1.00 29.10 ? 572 ASP A N 1 ATOM 4083 C CA . ASP A 1 266 ? 20.656 189.184 29.890 1.00 26.89 ? 572 ASP A CA 1 ATOM 4084 C C . ASP A 1 266 ? 19.276 189.547 30.427 1.00 26.01 ? 572 ASP A C 1 ATOM 4085 O O . ASP A 1 266 ? 18.300 188.874 30.081 1.00 26.22 ? 572 ASP A O 1 ATOM 4086 C CB . ASP A 1 266 ? 21.036 187.770 30.318 1.00 25.08 ? 572 ASP A CB 1 ATOM 4087 C CG . ASP A 1 266 ? 20.959 187.569 31.828 1.00 49.18 ? 572 ASP A CG 1 ATOM 4088 O OD1 . ASP A 1 266 ? 21.519 188.399 32.580 1.00 48.83 ? 572 ASP A OD1 1 ATOM 4089 O OD2 . ASP A 1 266 ? 20.336 186.579 32.268 1.00 55.26 ? 572 ASP A OD2 1 ATOM 4090 H H . ASP A 1 266 ? 22.212 189.810 30.925 1.00 34.92 ? 572 ASP A H 1 ATOM 4091 H HA . ASP A 1 266 ? 20.604 189.193 28.921 1.00 32.26 ? 572 ASP A HA 1 ATOM 4092 H HB2 . ASP A 1 266 ? 20.428 187.140 29.901 1.00 30.09 ? 572 ASP A HB2 1 ATOM 4093 H HB3 . ASP A 1 266 ? 21.946 187.589 30.038 1.00 30.09 ? 572 ASP A HB3 1 ATOM 4094 N N . ALA A 1 267 ? 19.156 190.597 31.243 1.00 20.35 ? 573 ALA A N 1 ATOM 4095 C CA . ALA A 1 267 ? 17.836 191.059 31.666 1.00 24.97 ? 573 ALA A CA 1 ATOM 4096 C C . ALA A 1 267 ? 17.077 191.786 30.555 1.00 19.82 ? 573 ALA A C 1 ATOM 4097 O O . ALA A 1 267 ? 15.858 191.952 30.665 1.00 17.12 ? 573 ALA A O 1 ATOM 4098 C CB . ALA A 1 267 ? 17.948 191.987 32.880 1.00 23.07 ? 573 ALA A CB 1 ATOM 4099 H H . ALA A 1 267 ? 19.814 191.051 31.560 1.00 24.43 ? 573 ALA A H 1 ATOM 4100 H HA . ALA A 1 267 ? 17.307 190.289 31.929 1.00 29.96 ? 573 ALA A HA 1 ATOM 4101 H HB1 . ALA A 1 267 ? 17.059 192.277 33.139 1.00 27.68 ? 573 ALA A HB1 1 ATOM 4102 H HB2 . ALA A 1 267 ? 18.363 191.501 33.611 1.00 27.68 ? 573 ALA A HB2 1 ATOM 4103 H HB3 . ALA A 1 267 ? 18.491 192.754 32.642 1.00 27.68 ? 573 ALA A HB3 1 ATOM 4104 N N . PHE A 1 268 ? 17.750 192.216 29.494 1.00 15.52 ? 574 PHE A N 1 ATOM 4105 C CA . PHE A 1 268 ? 17.093 192.988 28.445 1.00 20.60 ? 574 PHE A CA 1 ATOM 4106 C C . PHE A 1 268 ? 16.553 192.030 27.388 1.00 18.04 ? 574 PHE A C 1 ATOM 4107 O O . PHE A 1 268 ? 17.317 191.287 26.764 1.00 18.09 ? 574 PHE A O 1 ATOM 4108 C CB . PHE A 1 268 ? 18.061 194.015 27.856 1.00 18.55 ? 574 PHE A CB 1 ATOM 4109 C CG . PHE A 1 268 ? 18.481 195.072 28.848 1.00 17.71 ? 574 PHE A CG 1 ATOM 4110 C CD1 . PHE A 1 268 ? 19.563 194.865 29.686 1.00 17.15 ? 574 PHE A CD1 1 ATOM 4111 C CD2 . PHE A 1 268 ? 17.782 196.258 28.953 1.00 19.21 ? 574 PHE A CD2 1 ATOM 4112 C CE1 . PHE A 1 268 ? 19.946 195.808 30.595 1.00 18.47 ? 574 PHE A CE1 1 ATOM 4113 C CE2 . PHE A 1 268 ? 18.152 197.211 29.883 1.00 23.94 ? 574 PHE A CE2 1 ATOM 4114 C CZ . PHE A 1 268 ? 19.243 196.984 30.708 1.00 21.59 ? 574 PHE A CZ 1 ATOM 4115 H H . PHE A 1 268 ? 18.587 192.075 29.357 1.00 18.63 ? 574 PHE A H 1 ATOM 4116 H HA . PHE A 1 268 ? 16.342 193.468 28.827 1.00 24.72 ? 574 PHE A HA 1 ATOM 4117 H HB2 . PHE A 1 268 ? 18.860 193.556 27.552 1.00 22.26 ? 574 PHE A HB2 1 ATOM 4118 H HB3 . PHE A 1 268 ? 17.631 194.460 27.109 1.00 22.26 ? 574 PHE A HB3 1 ATOM 4119 H HD1 . PHE A 1 268 ? 20.042 194.070 29.624 1.00 20.57 ? 574 PHE A HD1 1 ATOM 4120 H HD2 . PHE A 1 268 ? 17.044 196.408 28.406 1.00 23.06 ? 574 PHE A HD2 1 ATOM 4121 H HE1 . PHE A 1 268 ? 20.677 195.649 31.148 1.00 22.16 ? 574 PHE A HE1 1 ATOM 4122 H HE2 . PHE A 1 268 ? 17.678 198.009 29.946 1.00 28.73 ? 574 PHE A HE2 1 ATOM 4123 H HZ . PHE A 1 268 ? 19.506 197.628 31.325 1.00 25.91 ? 574 PHE A HZ 1 ATOM 4124 N N . LEU A 1 269 ? 15.237 192.044 27.209 1.00 14.71 ? 575 LEU A N 1 ATOM 4125 C CA . LEU A 1 269 ? 14.504 191.035 26.462 1.00 16.52 ? 575 LEU A CA 1 ATOM 4126 C C . LEU A 1 269 ? 13.954 191.573 25.139 1.00 19.15 ? 575 LEU A C 1 ATOM 4127 O O . LEU A 1 269 ? 14.000 192.775 24.841 1.00 15.74 ? 575 LEU A O 1 ATOM 4128 C CB . LEU A 1 269 ? 13.334 190.516 27.296 1.00 20.44 ? 575 LEU A CB 1 ATOM 4129 C CG . LEU A 1 269 ? 13.628 190.018 28.700 1.00 25.13 ? 575 LEU A CG 1 ATOM 4130 C CD1 . LEU A 1 269 ? 12.320 189.697 29.393 1.00 24.97 ? 575 LEU A CD1 1 ATOM 4131 C CD2 . LEU A 1 269 ? 14.515 188.803 28.638 1.00 21.90 ? 575 LEU A CD2 1 ATOM 4132 H H . LEU A 1 269 ? 14.726 192.659 27.527 1.00 17.66 ? 575 LEU A H 1 ATOM 4133 H HA . LEU A 1 269 ? 15.094 190.290 26.266 1.00 19.83 ? 575 LEU A HA 1 ATOM 4134 H HB2 . LEU A 1 269 ? 12.686 191.234 27.381 1.00 24.53 ? 575 LEU A HB2 1 ATOM 4135 H HB3 . LEU A 1 269 ? 12.927 189.779 26.814 1.00 24.53 ? 575 LEU A HB3 1 ATOM 4136 H HG . LEU A 1 269 ? 14.084 190.711 29.203 1.00 30.16 ? 575 LEU A HG 1 ATOM 4137 H HD11 . LEU A 1 269 ? 12.508 189.378 30.290 1.00 29.96 ? 575 LEU A HD11 1 ATOM 4138 H HD12 . LEU A 1 269 ? 11.779 190.500 29.433 1.00 29.96 ? 575 LEU A HD12 1 ATOM 4139 H HD13 . LEU A 1 269 ? 11.856 189.010 28.888 1.00 29.96 ? 575 LEU A HD13 1 ATOM 4140 H HD21 . LEU A 1 269 ? 14.694 188.498 29.541 1.00 26.28 ? 575 LEU A HD21 1 ATOM 4141 H HD22 . LEU A 1 269 ? 14.062 188.108 28.137 1.00 26.28 ? 575 LEU A HD22 1 ATOM 4142 H HD23 . LEU A 1 269 ? 15.346 189.041 28.198 1.00 26.28 ? 575 LEU A HD23 1 ATOM 4143 N N . GLY A 1 270 ? 13.397 190.649 24.357 1.00 12.23 ? 576 GLY A N 1 ATOM 4144 C CA . GLY A 1 270 ? 12.541 191.000 23.239 1.00 16.52 ? 576 GLY A CA 1 ATOM 4145 C C . GLY A 1 270 ? 13.267 191.620 22.072 1.00 17.23 ? 576 GLY A C 1 ATOM 4146 O O . GLY A 1 270 ? 12.753 192.566 21.465 1.00 15.65 ? 576 GLY A O 1 ATOM 4147 H H . GLY A 1 270 ? 13.505 189.802 24.459 1.00 14.67 ? 576 GLY A H 1 ATOM 4148 H HA2 . GLY A 1 270 ? 12.090 190.201 22.922 1.00 19.82 ? 576 GLY A HA2 1 ATOM 4149 H HA3 . GLY A 1 270 ? 11.866 191.627 23.541 1.00 19.82 ? 576 GLY A HA3 1 ATOM 4150 N N . TRP A 1 271 ? 14.474 191.147 21.787 1.00 12.99 ? 577 TRP A N 1 ATOM 4151 C CA . TRP A 1 271 ? 15.218 191.531 20.604 1.00 15.55 ? 577 TRP A CA 1 ATOM 4152 C C . TRP A 1 271 ? 15.886 190.299 20.019 1.00 17.70 ? 577 TRP A C 1 ATOM 4153 O O . TRP A 1 271 ? 15.991 189.258 20.665 1.00 18.49 ? 577 TRP A O 1 ATOM 4154 C CB . TRP A 1 271 ? 16.286 192.584 20.898 1.00 17.06 ? 577 TRP A CB 1 ATOM 4155 C CG . TRP A 1 271 ? 17.329 192.168 21.873 1.00 17.64 ? 577 TRP A CG 1 ATOM 4156 C CD1 . TRP A 1 271 ? 17.255 192.251 23.239 1.00 19.00 ? 577 TRP A CD1 1 ATOM 4157 C CD2 . TRP A 1 271 ? 18.632 191.641 21.576 1.00 16.87 ? 577 TRP A CD2 1 ATOM 4158 N NE1 . TRP A 1 271 ? 18.424 191.799 23.804 1.00 13.87 ? 577 TRP A NE1 1 ATOM 4159 C CE2 . TRP A 1 271 ? 19.288 191.424 22.811 1.00 18.37 ? 577 TRP A CE2 1 ATOM 4160 C CE3 . TRP A 1 271 ? 19.306 191.329 20.396 1.00 15.85 ? 577 TRP A CE3 1 ATOM 4161 C CZ2 . TRP A 1 271 ? 20.580 190.898 22.891 1.00 18.63 ? 577 TRP A CZ2 1 ATOM 4162 C CZ3 . TRP A 1 271 ? 20.590 190.811 20.478 1.00 21.06 ? 577 TRP A CZ3 1 ATOM 4163 C CH2 . TRP A 1 271 ? 21.211 190.597 21.715 1.00 21.40 ? 577 TRP A CH2 1 ATOM 4164 H H . TRP A 1 271 ? 14.893 190.584 22.284 1.00 15.59 ? 577 TRP A H 1 ATOM 4165 H HA . TRP A 1 271 ? 14.607 191.892 19.942 1.00 18.66 ? 577 TRP A HA 1 ATOM 4166 H HB2 . TRP A 1 271 ? 16.735 192.808 20.068 1.00 20.47 ? 577 TRP A HB2 1 ATOM 4167 H HB3 . TRP A 1 271 ? 15.850 193.373 21.256 1.00 20.47 ? 577 TRP A HB3 1 ATOM 4168 H HD1 . TRP A 1 271 ? 16.523 192.570 23.714 1.00 22.80 ? 577 TRP A HD1 1 ATOM 4169 H HE1 . TRP A 1 271 ? 18.588 191.762 24.647 1.00 16.64 ? 577 TRP A HE1 1 ATOM 4170 H HE3 . TRP A 1 271 ? 18.902 191.466 19.569 1.00 19.02 ? 577 TRP A HE3 1 ATOM 4171 H HZ2 . TRP A 1 271 ? 20.993 190.755 23.711 1.00 22.36 ? 577 TRP A HZ2 1 ATOM 4172 H HZ3 . TRP A 1 271 ? 21.047 190.600 19.696 1.00 25.27 ? 577 TRP A HZ3 1 ATOM 4173 H HH2 . TRP A 1 271 ? 22.074 190.250 21.737 1.00 25.68 ? 577 TRP A HH2 1 ATOM 4174 N N . SER A 1 272 ? 16.337 190.421 18.779 1.00 20.51 ? 578 SER A N 1 ATOM 4175 C CA . SER A 1 272 ? 17.065 189.323 18.171 1.00 20.95 ? 578 SER A CA 1 ATOM 4176 C C . SER A 1 272 ? 17.948 189.914 17.080 1.00 23.81 ? 578 SER A C 1 ATOM 4177 O O . SER A 1 272 ? 18.220 191.116 17.084 1.00 16.08 ? 578 SER A O 1 ATOM 4178 C CB . SER A 1 272 ? 16.105 188.244 17.655 1.00 15.61 ? 578 SER A CB 1 ATOM 4179 O OG . SER A 1 272 ? 16.854 187.086 17.318 1.00 17.47 ? 578 SER A OG 1 ATOM 4180 H H . SER A 1 272 ? 16.237 191.113 18.279 1.00 24.61 ? 578 SER A H 1 ATOM 4181 H HA . SER A 1 272 ? 17.641 188.917 18.838 1.00 25.14 ? 578 SER A HA 1 ATOM 4182 H HB2 . SER A 1 272 ? 15.465 188.022 18.350 1.00 18.73 ? 578 SER A HB2 1 ATOM 4183 H HB3 . SER A 1 272 ? 15.646 188.571 16.865 1.00 18.73 ? 578 SER A HB3 1 ATOM 4184 H HG . SER A 1 272 ? 16.341 186.485 17.033 1.00 20.96 ? 578 SER A HG 1 ATOM 4185 N N . TYR A 1 273 ? 18.423 189.069 16.173 1.00 19.77 ? 579 TYR A N 1 ATOM 4186 C CA . TYR A 1 273 ? 19.412 189.524 15.214 1.00 23.40 ? 579 TYR A CA 1 ATOM 4187 C C . TYR A 1 273 ? 19.502 188.508 14.079 1.00 24.62 ? 579 TYR A C 1 ATOM 4188 O O . TYR A 1 273 ? 19.015 187.379 14.178 1.00 17.03 ? 579 TYR A O 1 ATOM 4189 C CB . TYR A 1 273 ? 20.773 189.738 15.891 1.00 20.22 ? 579 TYR A CB 1 ATOM 4190 C CG . TYR A 1 273 ? 21.418 188.451 16.382 1.00 23.86 ? 579 TYR A CG 1 ATOM 4191 C CD1 . TYR A 1 273 ? 21.096 187.915 17.630 1.00 35.19 ? 579 TYR A CD1 1 ATOM 4192 C CD2 . TYR A 1 273 ? 22.358 187.776 15.603 1.00 23.43 ? 579 TYR A CD2 1 ATOM 4193 C CE1 . TYR A 1 273 ? 21.689 186.730 18.082 1.00 28.60 ? 579 TYR A CE1 1 ATOM 4194 C CE2 . TYR A 1 273 ? 22.952 186.609 16.039 1.00 26.15 ? 579 TYR A CE2 1 ATOM 4195 C CZ . TYR A 1 273 ? 22.614 186.086 17.280 1.00 38.71 ? 579 TYR A CZ 1 ATOM 4196 O OH . TYR A 1 273 ? 23.201 184.914 17.709 1.00 47.03 ? 579 TYR A OH 1 ATOM 4197 H H . TYR A 1 273 ? 18.194 188.244 16.094 1.00 23.72 ? 579 TYR A H 1 ATOM 4198 H HA . TYR A 1 273 ? 19.125 190.372 14.840 1.00 28.08 ? 579 TYR A HA 1 ATOM 4199 H HB2 . TYR A 1 273 ? 21.379 190.149 15.255 1.00 24.27 ? 579 TYR A HB2 1 ATOM 4200 H HB3 . TYR A 1 273 ? 20.654 190.321 16.657 1.00 24.27 ? 579 TYR A HB3 1 ATOM 4201 H HD1 . TYR A 1 273 ? 20.472 188.348 18.167 1.00 42.23 ? 579 TYR A HD1 1 ATOM 4202 H HD2 . TYR A 1 273 ? 22.588 188.119 14.770 1.00 28.12 ? 579 TYR A HD2 1 ATOM 4203 H HE1 . TYR A 1 273 ? 21.463 186.379 18.913 1.00 34.32 ? 579 TYR A HE1 1 ATOM 4204 H HE2 . TYR A 1 273 ? 23.572 186.171 15.502 1.00 31.38 ? 579 TYR A HE2 1 ATOM 4205 H HH . TYR A 1 273 ? 23.738 184.633 17.128 1.00 56.44 ? 579 TYR A HH 1 ATOM 4206 N N . ASP A 1 274 ? 20.118 188.942 12.985 1.00 21.89 ? 580 ASP A N 1 ATOM 4207 C CA . ASP A 1 274 ? 20.346 188.077 11.838 1.00 21.19 ? 580 ASP A CA 1 ATOM 4208 C C . ASP A 1 274 ? 21.413 188.728 10.979 1.00 19.67 ? 580 ASP A C 1 ATOM 4209 O O . ASP A 1 274 ? 21.631 189.943 11.044 1.00 18.03 ? 580 ASP A O 1 ATOM 4210 C CB . ASP A 1 274 ? 19.062 187.840 11.033 1.00 17.04 ? 580 ASP A CB 1 ATOM 4211 C CG . ASP A 1 274 ? 19.180 186.658 10.082 1.00 23.53 ? 580 ASP A CG 1 ATOM 4212 O OD1 . ASP A 1 274 ? 20.217 185.965 10.149 1.00 25.50 ? 580 ASP A OD1 1 ATOM 4213 O OD2 . ASP A 1 274 ? 18.243 186.424 9.275 1.00 22.99 ? 580 ASP A OD2 1 ATOM 4214 H H . ASP A 1 274 ? 20.416 189.742 12.883 1.00 26.27 ? 580 ASP A H 1 ATOM 4215 H HA . ASP A 1 274 ? 20.679 187.218 12.143 1.00 25.43 ? 580 ASP A HA 1 ATOM 4216 H HB2 . ASP A 1 274 ? 18.332 187.661 11.646 1.00 20.45 ? 580 ASP A HB2 1 ATOM 4217 H HB3 . ASP A 1 274 ? 18.868 188.631 10.506 1.00 20.45 ? 580 ASP A HB3 1 ATOM 4218 N N . THR A 1 275 ? 22.093 187.911 10.188 1.00 18.35 ? 581 THR A N 1 ATOM 4219 C CA . THR A 1 275 ? 23.065 188.476 9.273 1.00 21.87 ? 581 THR A CA 1 ATOM 4220 C C . THR A 1 275 ? 22.341 189.266 8.192 1.00 21.48 ? 581 THR A C 1 ATOM 4221 O O . THR A 1 275 ? 21.169 189.016 7.888 1.00 23.00 ? 581 THR A O 1 ATOM 4222 C CB . THR A 1 275 ? 23.921 187.392 8.634 1.00 28.95 ? 581 THR A CB 1 ATOM 4223 O OG1 . THR A 1 275 ? 24.954 188.011 7.854 1.00 21.72 ? 581 THR A OG1 1 ATOM 4224 C CG2 . THR A 1 275 ? 23.062 186.484 7.745 1.00 23.66 ? 581 THR A CG2 1 ATOM 4225 H H . THR A 1 275 ? 22.013 187.055 10.161 1.00 22.01 ? 581 THR A H 1 ATOM 4226 H HA . THR A 1 275 ? 23.648 189.081 9.757 1.00 26.24 ? 581 THR A HA 1 ATOM 4227 H HB . THR A 1 275 ? 24.324 186.848 9.328 1.00 34.75 ? 581 THR A HB 1 ATOM 4228 H HG1 . THR A 1 275 ? 25.435 187.423 7.495 1.00 26.06 ? 581 THR A HG1 1 ATOM 4229 H HG21 . THR A 1 275 ? 23.615 185.797 7.341 1.00 28.39 ? 581 THR A HG21 1 ATOM 4230 H HG22 . THR A 1 275 ? 22.370 186.061 8.276 1.00 28.39 ? 581 THR A HG22 1 ATOM 4231 H HG23 . THR A 1 275 ? 22.646 187.007 7.042 1.00 28.39 ? 581 THR A HG23 1 ATOM 4232 N N . CYS A 1 276 ? 23.047 190.243 7.633 1.00 21.92 ? 582 CYS A N 1 ATOM 4233 C CA . CYS A 1 276 ? 22.576 190.993 6.473 1.00 24.91 ? 582 CYS A CA 1 ATOM 4234 C C . CYS A 1 276 ? 23.212 190.518 5.177 1.00 22.60 ? 582 CYS A C 1 ATOM 4235 O O . CYS A 1 276 ? 22.978 191.130 4.132 1.00 18.76 ? 582 CYS A O 1 ATOM 4236 C CB . CYS A 1 276 ? 22.866 192.480 6.636 1.00 13.09 ? 582 CYS A CB 1 ATOM 4237 S SG . CYS A 1 276 ? 24.601 192.873 6.883 1.00 18.23 ? 582 CYS A SG 1 ATOM 4238 H H . CYS A 1 276 ? 23.819 190.496 7.914 1.00 26.31 ? 582 CYS A H 1 ATOM 4239 H HA . CYS A 1 276 ? 21.615 190.881 6.393 1.00 29.89 ? 582 CYS A HA 1 ATOM 4240 H HB2 . CYS A 1 276 ? 22.570 192.945 5.838 1.00 15.71 ? 582 CYS A HB2 1 ATOM 4241 H HB3 . CYS A 1 276 ? 22.377 192.810 7.406 1.00 15.71 ? 582 CYS A HB3 1 ATOM 4242 N N . VAL A 1 277 ? 24.011 189.461 5.230 1.00 17.22 ? 583 VAL A N 1 ATOM 4243 C CA . VAL A 1 277 ? 24.842 189.045 4.109 1.00 17.57 ? 583 VAL A CA 1 ATOM 4244 C C . VAL A 1 277 ? 24.068 188.068 3.239 1.00 17.92 ? 583 VAL A C 1 ATOM 4245 O O . VAL A 1 277 ? 23.446 187.122 3.737 1.00 19.98 ? 583 VAL A O 1 ATOM 4246 C CB . VAL A 1 277 ? 26.151 188.396 4.591 1.00 22.77 ? 583 VAL A CB 1 ATOM 4247 C CG1 . VAL A 1 277 ? 26.960 187.830 3.386 1.00 17.16 ? 583 VAL A CG1 1 ATOM 4248 C CG2 . VAL A 1 277 ? 26.968 189.377 5.376 1.00 23.59 ? 583 VAL A CG2 1 ATOM 4249 H H . VAL A 1 277 ? 24.092 188.957 5.922 1.00 20.66 ? 583 VAL A H 1 ATOM 4250 H HA . VAL A 1 277 ? 25.067 189.820 3.571 1.00 21.08 ? 583 VAL A HA 1 ATOM 4251 H HB . VAL A 1 277 ? 25.935 187.654 5.178 1.00 27.33 ? 583 VAL A HB 1 ATOM 4252 H HG11 . VAL A 1 277 ? 27.779 187.427 3.717 1.00 20.59 ? 583 VAL A HG11 1 ATOM 4253 H HG12 . VAL A 1 277 ? 26.423 187.162 2.931 1.00 20.59 ? 583 VAL A HG12 1 ATOM 4254 H HG13 . VAL A 1 277 ? 27.170 188.556 2.778 1.00 20.59 ? 583 VAL A HG13 1 ATOM 4255 H HG21 . VAL A 1 277 ? 27.786 188.945 5.668 1.00 28.31 ? 583 VAL A HG21 1 ATOM 4256 H HG22 . VAL A 1 277 ? 27.179 190.136 4.811 1.00 28.31 ? 583 VAL A HG22 1 ATOM 4257 H HG23 . VAL A 1 277 ? 26.456 189.670 6.146 1.00 28.31 ? 583 VAL A HG23 1 ATOM 4258 N N . SER A 1 278 ? 24.140 188.289 1.935 1.00 22.79 ? 584 SER A N 1 ATOM 4259 C CA . SER A 1 278 ? 23.776 187.316 0.925 1.00 20.31 ? 584 SER A CA 1 ATOM 4260 C C . SER A 1 278 ? 24.617 187.645 -0.300 1.00 25.75 ? 584 SER A C 1 ATOM 4261 O O . SER A 1 278 ? 24.859 188.821 -0.593 1.00 22.75 ? 584 SER A O 1 ATOM 4262 C CB . SER A 1 278 ? 22.282 187.357 0.602 1.00 24.78 ? 584 SER A CB 1 ATOM 4263 O OG . SER A 1 278 ? 21.961 188.529 -0.141 1.00 23.77 ? 584 SER A OG 1 ATOM 4264 H H . SER A 1 278 ? 24.410 189.033 1.598 1.00 27.35 ? 584 SER A H 1 ATOM 4265 H HA . SER A 1 278 ? 24.005 186.424 1.230 1.00 24.38 ? 584 SER A HA 1 ATOM 4266 H HB2 . SER A 1 278 ? 22.050 186.576 0.076 1.00 29.74 ? 584 SER A HB2 1 ATOM 4267 H HB3 . SER A 1 278 ? 21.779 187.360 1.431 1.00 29.74 ? 584 SER A HB3 1 ATOM 4268 H HG . SER A 1 278 ? 22.158 189.214 0.304 1.00 28.52 ? 584 SER A HG 1 ATOM 4269 N N . ASN A 1 279 ? 25.090 186.599 -0.987 1.00 25.57 ? 585 ASN A N 1 ATOM 4270 C CA . ASN A 1 279 ? 26.023 186.745 -2.100 1.00 21.45 ? 585 ASN A CA 1 ATOM 4271 C C . ASN A 1 279 ? 27.238 187.592 -1.700 1.00 25.17 ? 585 ASN A C 1 ATOM 4272 O O . ASN A 1 279 ? 27.732 188.429 -2.461 1.00 23.37 ? 585 ASN A O 1 ATOM 4273 C CB . ASN A 1 279 ? 25.322 187.337 -3.318 1.00 30.07 ? 585 ASN A CB 1 ATOM 4274 C CG . ASN A 1 279 ? 26.226 187.364 -4.544 1.00 40.74 ? 585 ASN A CG 1 ATOM 4275 O OD1 . ASN A 1 279 ? 27.008 186.434 -4.759 1.00 40.42 ? 585 ASN A OD1 1 ATOM 4276 N ND2 . ASN A 1 279 ? 26.159 188.451 -5.326 1.00 39.20 ? 585 ASN A ND2 1 ATOM 4277 H H . ASN A 1 279 ? 24.878 185.782 -0.821 1.00 30.69 ? 585 ASN A H 1 ATOM 4278 H HA . ASN A 1 279 ? 26.348 185.866 -2.348 1.00 25.74 ? 585 ASN A HA 1 ATOM 4279 H HB2 . ASN A 1 279 ? 24.543 186.799 -3.528 1.00 36.08 ? 585 ASN A HB2 1 ATOM 4280 H HB3 . ASN A 1 279 ? 25.055 188.248 -3.119 1.00 36.08 ? 585 ASN A HB3 1 ATOM 4281 H HD21 . ASN A 1 279 ? 26.653 188.506 -6.028 1.00 47.04 ? 585 ASN A HD21 1 ATOM 4282 H HD22 . ASN A 1 279 ? 25.623 189.092 -5.126 1.00 47.04 ? 585 ASN A HD22 1 ATOM 4283 N N . ASN A 1 280 ? 27.725 187.364 -0.485 1.00 26.03 ? 586 ASN A N 1 ATOM 4284 C CA . ASN A 1 280 ? 28.899 188.042 0.067 1.00 28.55 ? 586 ASN A CA 1 ATOM 4285 C C . ASN A 1 280 ? 28.756 189.566 0.105 1.00 19.32 ? 586 ASN A C 1 ATOM 4286 O O . ASN A 1 280 ? 29.759 190.281 0.152 1.00 20.16 ? 586 ASN A O 1 ATOM 4287 C CB . ASN A 1 280 ? 30.163 187.629 -0.695 1.00 27.59 ? 586 ASN A CB 1 ATOM 4288 C CG . ASN A 1 280 ? 30.413 186.114 -0.609 1.00 32.49 ? 586 ASN A CG 1 ATOM 4289 O OD1 . ASN A 1 280 ? 30.697 185.572 0.461 1.00 27.06 ? 586 ASN A OD1 1 ATOM 4290 N ND2 . ASN A 1 280 ? 30.269 185.433 -1.728 1.00 33.20 ? 586 ASN A ND2 1 ATOM 4291 H H . ASN A 1 280 ? 27.379 186.797 0.061 1.00 31.23 ? 586 ASN A H 1 ATOM 4292 H HA . ASN A 1 280 ? 29.011 187.746 0.984 1.00 34.27 ? 586 ASN A HA 1 ATOM 4293 H HB2 . ASN A 1 280 ? 30.065 187.867 -1.630 1.00 33.10 ? 586 ASN A HB2 1 ATOM 4294 H HB3 . ASN A 1 280 ? 30.929 188.085 -0.312 1.00 33.10 ? 586 ASN A HB3 1 ATOM 4295 H HD21 . ASN A 1 280 ? 30.397 184.582 -1.733 1.00 39.84 ? 586 ASN A HD21 1 ATOM 4296 H HD22 . ASN A 1 280 ? 30.046 185.838 -2.453 1.00 39.84 ? 586 ASN A HD22 1 ATOM 4297 N N . ARG A 1 281 ? 27.533 190.085 0.100 1.00 18.85 ? 587 ARG A N 1 ATOM 4298 C CA . ARG A 1 281 ? 27.291 191.512 0.258 1.00 24.45 ? 587 ARG A CA 1 ATOM 4299 C C . ARG A 1 281 ? 26.254 191.743 1.349 1.00 24.32 ? 587 ARG A C 1 ATOM 4300 O O . ARG A 1 281 ? 25.330 190.941 1.533 1.00 19.63 ? 587 ARG A O 1 ATOM 4301 C CB . ARG A 1 281 ? 26.800 192.146 -1.043 1.00 28.39 ? 587 ARG A CB 1 ATOM 4302 C CG . ARG A 1 281 ? 27.571 191.706 -2.286 1.00 24.55 ? 587 ARG A CG 1 ATOM 4303 C CD . ARG A 1 281 ? 27.273 192.599 -3.499 1.00 30.78 ? 587 ARG A CD 1 ATOM 4304 N NE . ARG A 1 281 ? 28.356 193.561 -3.715 1.00 33.55 ? 587 ARG A NE 1 ATOM 4305 C CZ . ARG A 1 281 ? 28.269 194.871 -3.554 1.00 26.49 ? 587 ARG A CZ 1 ATOM 4306 N NH1 . ARG A 1 281 ? 27.138 195.446 -3.197 1.00 38.51 ? 587 ARG A NH1 1 ATOM 4307 N NH2 . ARG A 1 281 ? 29.330 195.616 -3.769 1.00 42.13 ? 587 ARG A NH2 1 ATOM 4308 H H . ARG A 1 281 ? 26.815 189.621 0.004 1.00 22.62 ? 587 ARG A H 1 ATOM 4309 H HA . ARG A 1 281 ? 28.115 191.951 0.521 1.00 29.34 ? 587 ARG A HA 1 ATOM 4310 H HB2 . ARG A 1 281 ? 25.869 191.908 -1.174 1.00 34.07 ? 587 ARG A HB2 1 ATOM 4311 H HB3 . ARG A 1 281 ? 26.884 193.110 -0.970 1.00 34.07 ? 587 ARG A HB3 1 ATOM 4312 H HG2 . ARG A 1 281 ? 28.523 191.753 -2.103 1.00 29.46 ? 587 ARG A HG2 1 ATOM 4313 H HG3 . ARG A 1 281 ? 27.319 190.796 -2.511 1.00 29.46 ? 587 ARG A HG3 1 ATOM 4314 H HD2 . ARG A 1 281 ? 27.190 192.047 -4.293 1.00 36.93 ? 587 ARG A HD2 1 ATOM 4315 H HD3 . ARG A 1 281 ? 26.452 193.091 -3.343 1.00 36.93 ? 587 ARG A HD3 1 ATOM 4316 H HE . ARG A 1 281 ? 29.115 193.247 -3.969 1.00 40.26 ? 587 ARG A HE 1 ATOM 4317 H HH11 . ARG A 1 281 ? 26.440 194.967 -3.052 1.00 46.21 ? 587 ARG A HH11 1 ATOM 4318 H HH12 . ARG A 1 281 ? 27.102 196.300 -3.102 1.00 46.21 ? 587 ARG A HH12 1 ATOM 4319 H HH21 . ARG A 1 281 ? 30.071 195.250 -4.008 1.00 50.55 ? 587 ARG A HH21 1 ATOM 4320 H HH22 . ARG A 1 281 ? 29.282 196.469 -3.677 1.00 50.55 ? 587 ARG A HH22 1 ATOM 4321 N N . CYS A 1 282 ? 26.406 192.846 2.077 1.00 19.60 ? 588 CYS A N 1 ATOM 4322 C CA A CYS A 1 282 ? 25.463 193.236 3.117 0.55 22.35 ? 588 CYS A CA 1 ATOM 4323 C CA B CYS A 1 282 ? 25.437 193.191 3.109 0.45 22.31 ? 588 CYS A CA 1 ATOM 4324 C C . CYS A 1 282 ? 24.327 194.019 2.475 1.00 21.91 ? 588 CYS A C 1 ATOM 4325 O O . CYS A 1 282 ? 24.581 195.021 1.794 1.00 16.50 ? 588 CYS A O 1 ATOM 4326 C CB A CYS A 1 282 ? 26.157 194.089 4.179 0.55 21.93 ? 588 CYS A CB 1 ATOM 4327 C CB B CYS A 1 282 ? 26.082 193.938 4.286 0.45 21.96 ? 588 CYS A CB 1 ATOM 4328 S SG A CYS A 1 282 ? 27.464 193.242 5.056 0.55 25.67 ? 588 CYS A SG 1 ATOM 4329 S SG B CYS A 1 282 ? 24.932 194.492 5.639 0.45 22.76 ? 588 CYS A SG 1 ATOM 4330 H H A CYS A 1 282 ? 27.062 193.395 1.983 0.55 23.52 ? 588 CYS A H 1 ATOM 4331 H H B CYS A 1 282 ? 27.055 193.405 1.993 0.45 23.52 ? 588 CYS A H 1 ATOM 4332 H HA A CYS A 1 282 ? 25.096 192.445 3.542 0.55 26.82 ? 588 CYS A HA 1 ATOM 4333 H HA B CYS A 1 282 ? 25.042 192.376 3.455 0.45 26.77 ? 588 CYS A HA 1 ATOM 4334 H HB2 A CYS A 1 282 ? 26.546 194.867 3.748 0.55 26.32 ? 588 CYS A HB2 1 ATOM 4335 H HB2 B CYS A 1 282 ? 26.743 193.355 4.691 0.45 26.35 ? 588 CYS A HB2 1 ATOM 4336 H HB3 A CYS A 1 282 ? 25.498 194.372 4.832 0.55 26.32 ? 588 CYS A HB3 1 ATOM 4337 H HB3 B CYS A 1 282 ? 26.521 194.731 3.939 0.45 26.35 ? 588 CYS A HB3 1 ATOM 4338 H HG A CYS A 1 282 ? 27.004 192.283 5.611 0.55 30.80 ? 588 CYS A HG 1 ATOM 4339 N N . ASN A 1 283 ? 23.097 193.571 2.684 1.00 14.84 ? 589 ASN A N 1 ATOM 4340 C CA . ASN A 1 283 ? 21.946 194.244 2.123 1.00 19.94 ? 589 ASN A CA 1 ATOM 4341 C C . ASN A 1 283 ? 21.504 195.348 3.054 1.00 20.91 ? 589 ASN A C 1 ATOM 4342 O O . ASN A 1 283 ? 21.509 195.177 4.277 1.00 17.87 ? 589 ASN A O 1 ATOM 4343 C CB . ASN A 1 283 ? 20.797 193.271 1.893 1.00 19.92 ? 589 ASN A CB 1 ATOM 4344 C CG . ASN A 1 283 ? 21.206 192.112 1.036 1.00 20.24 ? 589 ASN A CG 1 ATOM 4345 O OD1 . ASN A 1 283 ? 21.587 192.305 -0.122 1.00 17.72 ? 589 ASN A OD1 1 ATOM 4346 N ND2 . ASN A 1 283 ? 21.174 190.894 1.609 1.00 16.80 ? 589 ASN A ND2 1 ATOM 4347 H H . ASN A 1 283 ? 22.905 192.874 3.151 1.00 17.81 ? 589 ASN A H 1 ATOM 4348 H HA . ASN A 1 283 ? 22.187 194.639 1.271 1.00 23.93 ? 589 ASN A HA 1 ATOM 4349 H HB2 . ASN A 1 283 ? 20.497 192.923 2.747 1.00 23.90 ? 589 ASN A HB2 1 ATOM 4350 H HB3 . ASN A 1 283 ? 20.070 193.735 1.447 1.00 23.90 ? 589 ASN A HB3 1 ATOM 4351 H HD21 . ASN A 1 283 ? 21.401 190.199 1.155 1.00 20.16 ? 589 ASN A HD21 1 ATOM 4352 H HD22 . ASN A 1 283 ? 20.927 190.810 2.428 1.00 20.16 ? 589 ASN A HD22 1 ATOM 4353 N N . ILE A 1 284 ? 21.102 196.467 2.457 1.00 16.60 ? 590 ILE A N 1 ATOM 4354 C CA . ILE A 1 284 ? 20.876 197.711 3.170 1.00 13.58 ? 590 ILE A CA 1 ATOM 4355 C C . ILE A 1 284 ? 19.626 198.373 2.613 1.00 18.76 ? 590 ILE A C 1 ATOM 4356 O O . ILE A 1 284 ? 19.350 198.313 1.405 1.00 16.45 ? 590 ILE A O 1 ATOM 4357 C CB . ILE A 1 284 ? 22.086 198.657 3.051 1.00 17.66 ? 590 ILE A CB 1 ATOM 4358 C CG1 . ILE A 1 284 ? 23.380 197.914 3.409 1.00 15.48 ? 590 ILE A CG1 1 ATOM 4359 C CG2 . ILE A 1 284 ? 21.888 199.847 3.975 1.00 15.73 ? 590 ILE A CG2 1 ATOM 4360 C CD1 . ILE A 1 284 ? 24.621 198.719 3.187 1.00 23.80 ? 590 ILE A CD1 1 ATOM 4361 H H . ILE A 1 284 ? 20.949 196.527 1.613 1.00 19.92 ? 590 ILE A H 1 ATOM 4362 H HA . ILE A 1 284 ? 20.728 197.521 4.109 1.00 16.30 ? 590 ILE A HA 1 ATOM 4363 H HB . ILE A 1 284 ? 22.148 198.976 2.137 1.00 21.19 ? 590 ILE A HB 1 ATOM 4364 H HG12 . ILE A 1 284 ? 23.349 197.669 4.347 1.00 18.58 ? 590 ILE A HG12 1 ATOM 4365 H HG13 . ILE A 1 284 ? 23.442 197.115 2.863 1.00 18.58 ? 590 ILE A HG13 1 ATOM 4366 H HG21 . ILE A 1 284 ? 22.653 200.438 3.896 1.00 18.87 ? 590 ILE A HG21 1 ATOM 4367 H HG22 . ILE A 1 284 ? 21.079 200.315 3.717 1.00 18.87 ? 590 ILE A HG22 1 ATOM 4368 H HG23 . ILE A 1 284 ? 21.810 199.527 4.888 1.00 18.87 ? 590 ILE A HG23 1 ATOM 4369 H HD11 . ILE A 1 284 ? 25.392 198.185 3.434 1.00 28.56 ? 590 ILE A HD11 1 ATOM 4370 H HD12 . ILE A 1 284 ? 24.675 198.963 2.249 1.00 28.56 ? 590 ILE A HD12 1 ATOM 4371 H HD13 . ILE A 1 284 ? 24.582 199.518 3.735 1.00 28.56 ? 590 ILE A HD13 1 ATOM 4372 N N . PHE A 1 285 ? 18.875 199.010 3.503 1.00 14.05 ? 591 PHE A N 1 ATOM 4373 C CA . PHE A 1 285 ? 17.689 199.762 3.139 1.00 16.65 ? 591 PHE A CA 1 ATOM 4374 C C . PHE A 1 285 ? 17.920 201.248 3.364 1.00 18.31 ? 591 PHE A C 1 ATOM 4375 O O . PHE A 1 285 ? 18.627 201.657 4.293 1.00 17.34 ? 591 PHE A O 1 ATOM 4376 C CB . PHE A 1 285 ? 16.497 199.288 3.954 1.00 17.06 ? 591 PHE A CB 1 ATOM 4377 C CG . PHE A 1 285 ? 15.292 200.174 3.876 1.00 16.82 ? 591 PHE A CG 1 ATOM 4378 C CD1 . PHE A 1 285 ? 15.100 201.193 4.801 1.00 18.24 ? 591 PHE A CD1 1 ATOM 4379 C CD2 . PHE A 1 285 ? 14.311 199.939 2.936 1.00 17.44 ? 591 PHE A CD2 1 ATOM 4380 C CE1 . PHE A 1 285 ? 13.960 201.997 4.749 1.00 20.61 ? 591 PHE A CE1 1 ATOM 4381 C CE2 . PHE A 1 285 ? 13.173 200.726 2.878 1.00 16.34 ? 591 PHE A CE2 1 ATOM 4382 C CZ . PHE A 1 285 ? 12.992 201.757 3.784 1.00 16.68 ? 591 PHE A CZ 1 ATOM 4383 H H . PHE A 1 285 ? 19.040 199.019 4.347 1.00 16.86 ? 591 PHE A H 1 ATOM 4384 H HA . PHE A 1 285 ? 17.494 199.621 2.200 1.00 19.98 ? 591 PHE A HA 1 ATOM 4385 H HB2 . PHE A 1 285 ? 16.236 198.409 3.637 1.00 20.47 ? 591 PHE A HB2 1 ATOM 4386 H HB3 . PHE A 1 285 ? 16.761 199.233 4.886 1.00 20.47 ? 591 PHE A HB3 1 ATOM 4387 H HD1 . PHE A 1 285 ? 15.748 201.355 5.448 1.00 21.89 ? 591 PHE A HD1 1 ATOM 4388 H HD2 . PHE A 1 285 ? 14.421 199.249 2.322 1.00 20.93 ? 591 PHE A HD2 1 ATOM 4389 H HE1 . PHE A 1 285 ? 13.846 202.687 5.362 1.00 24.73 ? 591 PHE A HE1 1 ATOM 4390 H HE2 . PHE A 1 285 ? 12.530 200.563 2.227 1.00 19.61 ? 591 PHE A HE2 1 ATOM 4391 H HZ . PHE A 1 285 ? 12.231 202.289 3.742 1.00 20.01 ? 591 PHE A HZ 1 ATOM 4392 N N . SER A 1 286 ? 17.320 202.053 2.493 1.00 21.12 ? 592 SER A N 1 ATOM 4393 C CA . SER A 1 286 ? 17.338 203.495 2.672 1.00 13.79 ? 592 SER A CA 1 ATOM 4394 C C . SER A 1 286 ? 16.015 204.068 2.199 1.00 16.96 ? 592 SER A C 1 ATOM 4395 O O . SER A 1 286 ? 15.464 203.653 1.176 1.00 15.76 ? 592 SER A O 1 ATOM 4396 C CB . SER A 1 286 ? 18.495 204.156 1.932 1.00 22.69 ? 592 SER A CB 1 ATOM 4397 O OG . SER A 1 286 ? 18.518 205.543 2.233 1.00 31.75 ? 592 SER A OG 1 ATOM 4398 H H . SER A 1 286 ? 16.897 201.788 1.792 1.00 25.35 ? 592 SER A H 1 ATOM 4399 H HA . SER A 1 286 ? 17.432 203.695 3.617 1.00 16.55 ? 592 SER A HA 1 ATOM 4400 H HB2 . SER A 1 286 ? 19.330 203.753 2.218 1.00 27.22 ? 592 SER A HB2 1 ATOM 4401 H HB3 . SER A 1 286 ? 18.374 204.038 0.977 1.00 27.22 ? 592 SER A HB3 1 ATOM 4402 H HG . SER A 1 286 ? 18.618 205.656 3.059 1.00 38.10 ? 592 SER A HG 1 ATOM 4403 N N . ASN A 1 287 ? 15.502 205.003 2.977 1.00 20.69 ? 593 ASN A N 1 ATOM 4404 C CA . ASN A 1 287 ? 14.248 205.676 2.693 1.00 19.86 ? 593 ASN A CA 1 ATOM 4405 C C . ASN A 1 287 ? 14.559 207.130 2.353 1.00 17.78 ? 593 ASN A C 1 ATOM 4406 O O . ASN A 1 287 ? 15.406 207.758 2.992 1.00 20.61 ? 593 ASN A O 1 ATOM 4407 C CB . ASN A 1 287 ? 13.300 205.564 3.893 1.00 17.41 ? 593 ASN A CB 1 ATOM 4408 C CG . ASN A 1 287 ? 11.870 205.915 3.544 1.00 19.59 ? 593 ASN A CG 1 ATOM 4409 O OD1 . ASN A 1 287 ? 11.288 205.334 2.647 1.00 27.41 ? 593 ASN A OD1 1 ATOM 4410 N ND2 . ASN A 1 287 ? 11.287 206.846 4.277 1.00 32.16 ? 593 ASN A ND2 1 ATOM 4411 H H . ASN A 1 287 ? 15.875 205.274 3.703 1.00 24.83 ? 593 ASN A H 1 ATOM 4412 H HA . ASN A 1 287 ? 13.824 205.263 1.925 1.00 23.84 ? 593 ASN A HA 1 ATOM 4413 H HB2 . ASN A 1 287 ? 13.314 204.652 4.223 1.00 20.89 ? 593 ASN A HB2 1 ATOM 4414 H HB3 . ASN A 1 287 ? 13.597 206.173 4.588 1.00 20.89 ? 593 ASN A HB3 1 ATOM 4415 H HD21 . ASN A 1 287 ? 10.474 207.075 4.113 1.00 38.59 ? 593 ASN A HD21 1 ATOM 4416 H HD22 . ASN A 1 287 ? 11.719 207.222 4.918 1.00 38.59 ? 593 ASN A HD22 1 ATOM 4417 N N . PHE A 1 288 ? 13.918 207.634 1.311 1.00 20.91 ? 594 PHE A N 1 ATOM 4418 C CA . PHE A 1 288 ? 14.078 209.003 0.842 1.00 16.76 ? 594 PHE A CA 1 ATOM 4419 C C . PHE A 1 288 ? 12.774 209.724 1.114 1.00 19.45 ? 594 PHE A C 1 ATOM 4420 O O . PHE A 1 288 ? 11.727 209.312 0.608 1.00 21.79 ? 594 PHE A O 1 ATOM 4421 C CB . PHE A 1 288 ? 14.353 209.072 -0.659 1.00 19.21 ? 594 PHE A CB 1 ATOM 4422 C CG . PHE A 1 288 ? 15.702 208.584 -1.087 1.00 21.49 ? 594 PHE A CG 1 ATOM 4423 C CD1 . PHE A 1 288 ? 16.145 207.316 -0.777 1.00 26.17 ? 594 PHE A CD1 1 ATOM 4424 C CD2 . PHE A 1 288 ? 16.506 209.389 -1.867 1.00 26.98 ? 594 PHE A CD2 1 ATOM 4425 C CE1 . PHE A 1 288 ? 17.396 206.881 -1.214 1.00 23.80 ? 594 PHE A CE1 1 ATOM 4426 C CE2 . PHE A 1 288 ? 17.743 208.962 -2.307 1.00 27.64 ? 594 PHE A CE2 1 ATOM 4427 C CZ . PHE A 1 288 ? 18.187 207.713 -1.987 1.00 27.96 ? 594 PHE A CZ 1 ATOM 4428 H H . PHE A 1 288 ? 13.360 207.182 0.838 1.00 25.09 ? 594 PHE A H 1 ATOM 4429 H HA . PHE A 1 288 ? 14.797 209.444 1.322 1.00 20.11 ? 594 PHE A HA 1 ATOM 4430 H HB2 . PHE A 1 288 ? 13.690 208.533 -1.118 1.00 23.05 ? 594 PHE A HB2 1 ATOM 4431 H HB3 . PHE A 1 288 ? 14.274 209.996 -0.944 1.00 23.05 ? 594 PHE A HB3 1 ATOM 4432 H HD1 . PHE A 1 288 ? 15.615 206.754 -0.260 1.00 31.41 ? 594 PHE A HD1 1 ATOM 4433 H HD2 . PHE A 1 288 ? 16.212 210.242 -2.094 1.00 32.38 ? 594 PHE A HD2 1 ATOM 4434 H HE1 . PHE A 1 288 ? 17.695 206.028 -0.993 1.00 28.56 ? 594 PHE A HE1 1 ATOM 4435 H HE2 . PHE A 1 288 ? 18.274 209.526 -2.823 1.00 33.17 ? 594 PHE A HE2 1 ATOM 4436 H HZ . PHE A 1 288 ? 19.022 207.425 -2.276 1.00 33.55 ? 594 PHE A HZ 1 ATOM 4437 N N . ILE A 1 289 ? 12.826 210.797 1.888 1.00 16.68 ? 595 ILE A N 1 ATOM 4438 C CA . ILE A 1 289 ? 11.682 211.681 2.035 1.00 23.58 ? 595 ILE A CA 1 ATOM 4439 C C . ILE A 1 289 ? 11.954 212.901 1.158 1.00 20.43 ? 595 ILE A C 1 ATOM 4440 O O . ILE A 1 289 ? 12.970 213.583 1.329 1.00 19.60 ? 595 ILE A O 1 ATOM 4441 C CB . ILE A 1 289 ? 11.452 212.076 3.504 1.00 22.83 ? 595 ILE A CB 1 ATOM 4442 C CG1 . ILE A 1 289 ? 11.333 210.833 4.405 1.00 35.68 ? 595 ILE A CG1 1 ATOM 4443 C CG2 . ILE A 1 289 ? 10.207 212.954 3.632 1.00 23.03 ? 595 ILE A CG2 1 ATOM 4444 C CD1 . ILE A 1 289 ? 10.098 209.984 4.157 1.00 37.09 ? 595 ILE A CD1 1 ATOM 4445 H H . ILE A 1 289 ? 13.516 211.036 2.342 1.00 20.02 ? 595 ILE A H 1 ATOM 4446 H HA . ILE A 1 289 ? 10.885 211.237 1.707 1.00 28.30 ? 595 ILE A HA 1 ATOM 4447 H HB . ILE A 1 289 ? 12.218 212.592 3.801 1.00 27.40 ? 595 ILE A HB 1 ATOM 4448 H HG12 . ILE A 1 289 ? 12.110 210.270 4.260 1.00 42.82 ? 595 ILE A HG12 1 ATOM 4449 H HG13 . ILE A 1 289 ? 11.310 211.123 5.330 1.00 42.82 ? 595 ILE A HG13 1 ATOM 4450 H HG21 . ILE A 1 289 ? 10.082 213.191 4.565 1.00 27.64 ? 595 ILE A HG21 1 ATOM 4451 H HG22 . ILE A 1 289 ? 10.330 213.757 3.101 1.00 27.64 ? 595 ILE A HG22 1 ATOM 4452 H HG23 . ILE A 1 289 ? 9.437 212.459 3.310 1.00 27.64 ? 595 ILE A HG23 1 ATOM 4453 H HD11 . ILE A 1 289 ? 10.107 209.229 4.766 1.00 44.51 ? 595 ILE A HD11 1 ATOM 4454 H HD12 . ILE A 1 289 ? 9.307 210.525 4.312 1.00 44.51 ? 595 ILE A HD12 1 ATOM 4455 H HD13 . ILE A 1 289 ? 10.110 209.670 3.239 1.00 44.51 ? 595 ILE A HD13 1 ATOM 4456 N N . LEU A 1 290 ? 11.069 213.161 0.202 1.00 23.91 ? 596 LEU A N 1 ATOM 4457 C CA . LEU A 1 290 ? 11.208 214.288 -0.726 1.00 21.90 ? 596 LEU A CA 1 ATOM 4458 C C . LEU A 1 290 ? 10.311 215.424 -0.249 1.00 21.14 ? 596 LEU A C 1 ATOM 4459 O O . LEU A 1 290 ? 9.092 215.364 -0.418 1.00 21.97 ? 596 LEU A O 1 ATOM 4460 C CB . LEU A 1 290 ? 10.828 213.878 -2.144 1.00 21.16 ? 596 LEU A CB 1 ATOM 4461 C CG . LEU A 1 290 ? 11.471 212.593 -2.664 1.00 24.43 ? 596 LEU A CG 1 ATOM 4462 C CD1 . LEU A 1 290 ? 10.923 212.221 -4.037 1.00 31.73 ? 596 LEU A CD1 1 ATOM 4463 C CD2 . LEU A 1 290 ? 12.978 212.750 -2.714 1.00 27.20 ? 596 LEU A CD2 1 ATOM 4464 H H . LEU A 1 290 ? 10.361 212.692 0.065 1.00 28.69 ? 596 LEU A H 1 ATOM 4465 H HA . LEU A 1 290 ? 12.128 214.597 -0.728 1.00 26.28 ? 596 LEU A HA 1 ATOM 4466 H HB2 . LEU A 1 290 ? 9.866 213.755 -2.178 1.00 25.39 ? 596 LEU A HB2 1 ATOM 4467 H HB3 . LEU A 1 290 ? 11.083 214.594 -2.747 1.00 25.39 ? 596 LEU A HB3 1 ATOM 4468 H HG . LEU A 1 290 ? 11.265 211.868 -2.053 1.00 29.31 ? 596 LEU A HG 1 ATOM 4469 H HD11 . LEU A 1 290 ? 11.350 211.404 -4.336 1.00 38.08 ? 596 LEU A HD11 1 ATOM 4470 H HD12 . LEU A 1 290 ? 9.964 212.088 -3.968 1.00 38.08 ? 596 LEU A HD12 1 ATOM 4471 H HD13 . LEU A 1 290 ? 11.113 212.942 -4.658 1.00 38.08 ? 596 LEU A HD13 1 ATOM 4472 H HD21 . LEU A 1 290 ? 13.369 211.926 -3.045 1.00 32.64 ? 596 LEU A HD21 1 ATOM 4473 H HD22 . LEU A 1 290 ? 13.199 213.484 -3.307 1.00 32.64 ? 596 LEU A HD22 1 ATOM 4474 H HD23 . LEU A 1 290 ? 13.305 212.935 -1.820 1.00 32.64 ? 596 LEU A HD23 1 ATOM 4475 N N . ASN A 1 291 ? 10.907 216.460 0.337 1.00 19.77 ? 597 ASN A N 1 ATOM 4476 C CA . ASN A 1 291 ? 10.144 217.596 0.844 1.00 27.24 ? 597 ASN A CA 1 ATOM 4477 C C . ASN A 1 291 ? 10.092 218.720 -0.185 1.00 25.61 ? 597 ASN A C 1 ATOM 4478 O O . ASN A 1 291 ? 11.133 219.179 -0.669 1.00 25.49 ? 597 ASN A O 1 ATOM 4479 C CB . ASN A 1 291 ? 10.744 218.117 2.146 1.00 22.27 ? 597 ASN A CB 1 ATOM 4480 C CG . ASN A 1 291 ? 10.692 217.084 3.247 1.00 26.49 ? 597 ASN A CG 1 ATOM 4481 O OD1 . ASN A 1 291 ? 9.629 216.547 3.559 1.00 26.27 ? 597 ASN A OD1 1 ATOM 4482 N ND2 . ASN A 1 291 ? 11.846 216.769 3.813 1.00 25.70 ? 597 ASN A ND2 1 ATOM 4483 H H . ASN A 1 291 ? 11.756 216.528 0.454 1.00 23.72 ? 597 ASN A H 1 ATOM 4484 H HA . ASN A 1 291 ? 9.235 217.312 1.025 1.00 32.69 ? 597 ASN A HA 1 ATOM 4485 H HB2 . ASN A 1 291 ? 11.673 218.352 1.997 1.00 26.72 ? 597 ASN A HB2 1 ATOM 4486 H HB3 . ASN A 1 291 ? 10.245 218.895 2.438 1.00 26.72 ? 597 ASN A HB3 1 ATOM 4487 H HD21 . ASN A 1 291 ? 11.870 216.186 4.445 1.00 30.84 ? 597 ASN A HD21 1 ATOM 4488 H HD22 . ASN A 1 291 ? 12.572 217.147 3.550 1.00 30.84 ? 597 ASN A HD22 1 ATOM 4489 N N . GLY A 1 292 ? 8.881 219.168 -0.499 1.00 27.97 ? 598 GLY A N 1 ATOM 4490 C CA . GLY A 1 292 ? 8.705 220.414 -1.214 1.00 29.36 ? 598 GLY A CA 1 ATOM 4491 C C . GLY A 1 292 ? 9.113 220.365 -2.671 1.00 27.26 ? 598 GLY A C 1 ATOM 4492 O O . GLY A 1 292 ? 9.892 221.204 -3.125 1.00 27.11 ? 598 GLY A O 1 ATOM 4493 H H . GLY A 1 292 ? 8.147 218.765 -0.306 1.00 33.57 ? 598 GLY A H 1 ATOM 4494 H HA2 . GLY A 1 292 ? 7.771 220.673 -1.172 1.00 35.23 ? 598 GLY A HA2 1 ATOM 4495 H HA3 . GLY A 1 292 ? 9.229 221.105 -0.778 1.00 35.23 ? 598 GLY A HA3 1 ATOM 4496 N N . ILE A 1 293 ? 8.587 219.383 -3.408 1.00 28.97 ? 599 ILE A N 1 ATOM 4497 C CA . ILE A 1 293 ? 8.836 219.284 -4.843 1.00 34.13 ? 599 ILE A CA 1 ATOM 4498 C C . ILE A 1 293 ? 8.563 220.622 -5.526 1.00 27.44 ? 599 ILE A C 1 ATOM 4499 O O . ILE A 1 293 ? 7.579 221.306 -5.228 1.00 31.17 ? 599 ILE A O 1 ATOM 4500 C CB . ILE A 1 293 ? 7.972 218.162 -5.451 1.00 29.73 ? 599 ILE A CB 1 ATOM 4501 C CG1 . ILE A 1 293 ? 8.095 218.136 -6.978 1.00 40.61 ? 599 ILE A CG1 1 ATOM 4502 C CG2 . ILE A 1 293 ? 6.505 218.321 -5.052 1.00 29.08 ? 599 ILE A CG2 1 ATOM 4503 C CD1 . ILE A 1 293 ? 9.499 217.881 -7.491 1.00 40.59 ? 599 ILE A CD1 1 ATOM 4504 H H . ILE A 1 293 ? 8.081 218.761 -3.097 1.00 34.77 ? 599 ILE A H 1 ATOM 4505 H HA . ILE A 1 293 ? 9.768 219.057 -4.988 1.00 40.96 ? 599 ILE A HA 1 ATOM 4506 H HB . ILE A 1 293 ? 8.290 217.313 -5.106 1.00 35.68 ? 599 ILE A HB 1 ATOM 4507 H HG12 . ILE A 1 293 ? 7.523 217.433 -7.323 1.00 48.73 ? 599 ILE A HG12 1 ATOM 4508 H HG13 . ILE A 1 293 ? 7.805 218.993 -7.327 1.00 48.73 ? 599 ILE A HG13 1 ATOM 4509 H HG21 . ILE A 1 293 ? 5.990 217.601 -5.450 1.00 34.90 ? 599 ILE A HG21 1 ATOM 4510 H HG22 . ILE A 1 293 ? 6.435 218.283 -4.085 1.00 34.90 ? 599 ILE A HG22 1 ATOM 4511 H HG23 . ILE A 1 293 ? 6.182 219.177 -5.374 1.00 34.90 ? 599 ILE A HG23 1 ATOM 4512 H HD11 . ILE A 1 293 ? 9.485 217.881 -8.460 1.00 48.71 ? 599 ILE A HD11 1 ATOM 4513 H HD12 . ILE A 1 293 ? 10.085 218.583 -7.167 1.00 48.71 ? 599 ILE A HD12 1 ATOM 4514 H HD13 . ILE A 1 293 ? 9.802 217.019 -7.164 1.00 48.71 ? 599 ILE A HD13 1 ATOM 4515 N N . ASN A 1 294 ? 9.444 220.990 -6.456 1.00 28.78 ? 600 ASN A N 1 ATOM 4516 C CA . ASN A 1 294 ? 9.305 222.218 -7.235 1.00 34.85 ? 600 ASN A CA 1 ATOM 4517 C C . ASN A 1 294 ? 9.393 223.435 -6.320 1.00 28.32 ? 600 ASN A C 1 ATOM 4518 O O . ASN A 1 294 ? 8.562 224.340 -6.355 1.00 33.90 ? 600 ASN A O 1 ATOM 4519 C CB . ASN A 1 294 ? 8.006 222.221 -8.044 1.00 36.37 ? 600 ASN A CB 1 ATOM 4520 C CG . ASN A 1 294 ? 7.960 221.109 -9.069 1.00 40.33 ? 600 ASN A CG 1 ATOM 4521 O OD1 . ASN A 1 294 ? 8.992 220.560 -9.462 1.00 41.43 ? 600 ASN A OD1 1 ATOM 4522 N ND2 . ASN A 1 294 ? 6.762 220.779 -9.520 1.00 41.88 ? 600 ASN A ND2 1 ATOM 4523 H H . ASN A 1 294 ? 10.145 220.534 -6.656 1.00 34.54 ? 600 ASN A H 1 ATOM 4524 H HA . ASN A 1 294 ? 10.042 222.270 -7.864 1.00 41.82 ? 600 ASN A HA 1 ATOM 4525 H HB2 . ASN A 1 294 ? 7.256 222.103 -7.439 1.00 43.64 ? 600 ASN A HB2 1 ATOM 4526 H HB3 . ASN A 1 294 ? 7.926 223.066 -8.513 1.00 43.64 ? 600 ASN A HB3 1 ATOM 4527 H HD21 . ASN A 1 294 ? 6.679 220.153 -10.104 1.00 50.26 ? 600 ASN A HD21 1 ATOM 4528 H HD22 . ASN A 1 294 ? 6.064 221.189 -9.229 1.00 50.26 ? 600 ASN A HD22 1 ATOM 4529 N N . SER A 1 295 ? 10.410 223.420 -5.469 1.00 31.84 ? 601 SER A N 1 ATOM 4530 C CA . SER A 1 295 ? 10.756 224.520 -4.582 1.00 25.94 ? 601 SER A CA 1 ATOM 4531 C C . SER A 1 295 ? 12.116 224.169 -4.001 1.00 25.68 ? 601 SER A C 1 ATOM 4532 O O . SER A 1 295 ? 12.584 223.035 -4.121 1.00 21.26 ? 601 SER A O 1 ATOM 4533 C CB . SER A 1 295 ? 9.711 224.739 -3.483 1.00 31.45 ? 601 SER A CB 1 ATOM 4534 O OG . SER A 1 295 ? 9.800 223.752 -2.456 1.00 33.95 ? 601 SER A OG 1 ATOM 4535 H H . SER A 1 295 ? 10.939 222.748 -5.385 1.00 38.21 ? 601 SER A H 1 ATOM 4536 H HA . SER A 1 295 ? 10.841 225.339 -5.095 1.00 31.12 ? 601 SER A HA 1 ATOM 4537 H HB2 . SER A 1 295 ? 9.852 225.614 -3.088 1.00 37.74 ? 601 SER A HB2 1 ATOM 4538 H HB3 . SER A 1 295 ? 8.827 224.696 -3.880 1.00 37.74 ? 601 SER A HB3 1 ATOM 4539 H HG . SER A 1 295 ? 9.677 222.987 -2.780 1.00 40.73 ? 601 SER A HG 1 ATOM 4540 N N . GLY A 1 296 ? 12.755 225.156 -3.409 1.00 23.77 ? 602 GLY A N 1 ATOM 4541 C CA . GLY A 1 296 ? 14.004 224.941 -2.731 1.00 21.97 ? 602 GLY A CA 1 ATOM 4542 C C . GLY A 1 296 ? 15.188 224.868 -3.663 1.00 17.68 ? 602 GLY A C 1 ATOM 4543 O O . GLY A 1 296 ? 15.103 225.086 -4.874 1.00 22.49 ? 602 GLY A O 1 ATOM 4544 H H . GLY A 1 296 ? 12.480 225.970 -3.388 1.00 28.52 ? 602 GLY A H 1 ATOM 4545 H HA2 . GLY A 1 296 ? 14.156 225.665 -2.103 1.00 26.36 ? 602 GLY A HA2 1 ATOM 4546 H HA3 . GLY A 1 296 ? 13.958 224.110 -2.232 1.00 26.36 ? 602 GLY A HA3 1 ATOM 4547 N N . THR A 1 297 ? 16.331 224.535 -3.062 1.00 22.91 ? 603 THR A N 1 ATOM 4548 C CA . THR A 1 297 ? 17.600 224.526 -3.776 1.00 26.33 ? 603 THR A CA 1 ATOM 4549 C C . THR A 1 297 ? 18.331 223.190 -3.655 1.00 24.17 ? 603 THR A C 1 ATOM 4550 O O . THR A 1 297 ? 19.555 223.142 -3.818 1.00 26.27 ? 603 THR A O 1 ATOM 4551 C CB . THR A 1 297 ? 18.476 225.673 -3.273 1.00 32.24 ? 603 THR A CB 1 ATOM 4552 O OG1 . THR A 1 297 ? 18.624 225.576 -1.853 1.00 29.01 ? 603 THR A OG1 1 ATOM 4553 C CG2 . THR A 1 297 ? 17.826 227.007 -3.634 1.00 28.24 ? 603 THR A CG2 1 ATOM 4554 H H . THR A 1 297 ? 16.394 224.309 -2.235 1.00 27.50 ? 603 THR A H 1 ATOM 4555 H HA . THR A 1 297 ? 17.426 224.680 -4.718 1.00 31.59 ? 603 THR A HA 1 ATOM 4556 H HB . THR A 1 297 ? 19.347 225.628 -3.695 1.00 38.69 ? 603 THR A HB 1 ATOM 4557 H HG1 . THR A 1 297 ? 19.105 226.205 -1.571 1.00 34.81 ? 603 THR A HG1 1 ATOM 4558 H HG21 . THR A 1 297 ? 18.377 227.740 -3.317 1.00 33.89 ? 603 THR A HG21 1 ATOM 4559 H HG22 . THR A 1 297 ? 17.729 227.079 -4.596 1.00 33.89 ? 603 THR A HG22 1 ATOM 4560 H HG23 . THR A 1 297 ? 16.950 227.071 -3.223 1.00 33.89 ? 603 THR A HG23 1 ATOM 4561 N N . THR A 1 298 ? 17.609 222.108 -3.383 1.00 23.10 ? 604 THR A N 1 ATOM 4562 C CA . THR A 1 298 ? 18.148 220.749 -3.460 1.00 19.45 ? 604 THR A CA 1 ATOM 4563 C C . THR A 1 298 ? 17.694 220.234 -4.814 1.00 21.82 ? 604 THR A C 1 ATOM 4564 O O . THR A 1 298 ? 16.558 219.777 -4.967 1.00 20.12 ? 604 THR A O 1 ATOM 4565 C CB . THR A 1 298 ? 17.636 219.880 -2.318 1.00 27.10 ? 604 THR A CB 1 ATOM 4566 O OG1 . THR A 1 298 ? 17.684 220.615 -1.088 1.00 23.70 ? 604 THR A OG1 1 ATOM 4567 C CG2 . THR A 1 298 ? 18.473 218.621 -2.175 1.00 27.31 ? 604 THR A CG2 1 ATOM 4568 H H . THR A 1 298 ? 16.782 222.134 -3.145 1.00 27.72 ? 604 THR A H 1 ATOM 4569 H HA . THR A 1 298 ? 19.117 220.772 -3.435 1.00 23.34 ? 604 THR A HA 1 ATOM 4570 H HB . THR A 1 298 ? 16.720 219.619 -2.499 1.00 32.52 ? 604 THR A HB 1 ATOM 4571 H HG1 . THR A 1 298 ? 17.205 221.303 -1.145 1.00 28.44 ? 604 THR A HG1 1 ATOM 4572 H HG21 . THR A 1 298 ? 18.134 218.080 -1.444 1.00 32.77 ? 604 THR A HG21 1 ATOM 4573 H HG22 . THR A 1 298 ? 18.435 218.104 -2.994 1.00 32.77 ? 604 THR A HG22 1 ATOM 4574 H HG23 . THR A 1 298 ? 19.396 218.856 -1.992 1.00 32.77 ? 604 THR A HG23 1 ATOM 4575 N N . CYS A 1 299 ? 18.574 220.328 -5.802 1.00 18.89 ? 605 CYS A N 1 ATOM 4576 C CA A CYS A 1 299 ? 18.168 220.187 -7.190 0.53 24.70 ? 605 CYS A CA 1 ATOM 4577 C CA B CYS A 1 299 ? 18.217 220.230 -7.210 0.47 24.72 ? 605 CYS A CA 1 ATOM 4578 C C . CYS A 1 299 ? 18.960 219.076 -7.858 1.00 24.93 ? 605 CYS A C 1 ATOM 4579 O O . CYS A 1 299 ? 20.142 218.866 -7.571 1.00 26.50 ? 605 CYS A O 1 ATOM 4580 C CB A CYS A 1 299 ? 18.345 221.505 -7.981 0.53 25.71 ? 605 CYS A CB 1 ATOM 4581 C CB B CYS A 1 299 ? 18.583 221.525 -7.946 0.47 25.57 ? 605 CYS A CB 1 ATOM 4582 S SG A CYS A 1 299 ? 17.364 222.942 -7.395 0.53 16.50 ? 605 CYS A SG 1 ATOM 4583 S SG B CYS A 1 299 ? 18.719 222.976 -6.872 0.47 19.69 ? 605 CYS A SG 1 ATOM 4584 H H A CYS A 1 299 ? 19.415 220.474 -5.694 0.53 22.67 ? 605 CYS A H 1 ATOM 4585 H H B CYS A 1 299 ? 19.416 220.454 -5.676 0.47 22.67 ? 605 CYS A H 1 ATOM 4586 H HA A CYS A 1 299 ? 17.229 219.944 -7.220 0.53 29.64 ? 605 CYS A HA 1 ATOM 4587 H HA B CYS A 1 299 ? 17.263 220.077 -7.298 0.47 29.67 ? 605 CYS A HA 1 ATOM 4588 H HB2 A CYS A 1 299 ? 19.280 221.759 -7.942 0.53 30.85 ? 605 CYS A HB2 1 ATOM 4589 H HB2 B CYS A 1 299 ? 19.439 221.402 -8.386 0.47 30.68 ? 605 CYS A HB2 1 ATOM 4590 H HB3 A CYS A 1 299 ? 18.095 221.342 -8.904 0.53 30.85 ? 605 CYS A HB3 1 ATOM 4591 H HB3 B CYS A 1 299 ? 17.898 221.710 -8.608 0.47 30.68 ? 605 CYS A HB3 1 ATOM 4592 H HG B CYS A 1 299 ? 17.666 223.159 -6.327 0.47 23.63 ? 605 CYS A HG 1 ATOM 4593 N N . SER A 1 300 ? 18.280 218.358 -8.743 1.00 25.06 ? 606 SER A N 1 ATOM 4594 C CA . SER A 1 300 ? 18.922 217.325 -9.543 1.00 31.33 ? 606 SER A CA 1 ATOM 4595 C C . SER A 1 300 ? 19.674 217.953 -10.712 1.00 29.74 ? 606 SER A C 1 ATOM 4596 O O . SER A 1 300 ? 19.162 218.852 -11.384 1.00 24.34 ? 606 SER A O 1 ATOM 4597 C CB . SER A 1 300 ? 17.886 216.330 -10.068 1.00 25.69 ? 606 SER A CB 1 ATOM 4598 O OG . SER A 1 300 ? 18.295 215.799 -11.313 1.00 27.51 ? 606 SER A OG 1 ATOM 4599 H H . SER A 1 300 ? 17.439 218.451 -8.900 1.00 30.08 ? 606 SER A H 1 ATOM 4600 H HA . SER A 1 300 ? 19.559 216.842 -8.993 1.00 37.59 ? 606 SER A HA 1 ATOM 4601 H HB2 . SER A 1 300 ? 17.791 215.605 -9.430 1.00 30.83 ? 606 SER A HB2 1 ATOM 4602 H HB3 . SER A 1 300 ? 17.038 216.786 -10.182 1.00 30.83 ? 606 SER A HB3 1 ATOM 4603 H HG . SER A 1 300 ? 19.031 215.402 -11.228 1.00 33.02 ? 606 SER A HG 1 ATOM 4604 N N . ASN A 1 301 ? 20.901 217.475 -10.943 1.00 31.95 ? 607 ASN A N 1 ATOM 4605 C CA . ASN A 1 301 ? 21.705 217.864 -12.097 1.00 37.11 ? 607 ASN A CA 1 ATOM 4606 C C . ASN A 1 301 ? 21.695 216.808 -13.200 1.00 40.37 ? 607 ASN A C 1 ATOM 4607 O O . ASN A 1 301 ? 22.586 216.810 -14.059 1.00 35.26 ? 607 ASN A O 1 ATOM 4608 C CB . ASN A 1 301 ? 23.148 218.142 -11.673 1.00 37.37 ? 607 ASN A CB 1 ATOM 4609 C CG . ASN A 1 301 ? 23.346 219.559 -11.197 1.00 46.28 ? 607 ASN A CG 1 ATOM 4610 O OD1 . ASN A 1 301 ? 22.464 220.408 -11.356 1.00 49.28 ? 607 ASN A OD1 1 ATOM 4611 N ND2 . ASN A 1 301 ? 24.512 219.832 -10.617 1.00 51.30 ? 607 ASN A ND2 1 ATOM 4612 H H . ASN A 1 301 ? 21.295 216.909 -10.430 1.00 38.34 ? 607 ASN A H 1 ATOM 4613 H HA . ASN A 1 301 ? 21.341 218.683 -12.469 1.00 44.54 ? 607 ASN A HA 1 ATOM 4614 H HB2 . ASN A 1 301 ? 23.386 217.545 -10.947 1.00 44.85 ? 607 ASN A HB2 1 ATOM 4615 H HB3 . ASN A 1 301 ? 23.735 217.995 -12.431 1.00 44.85 ? 607 ASN A HB3 1 ATOM 4616 H HD21 . ASN A 1 301 ? 24.673 220.626 -10.328 1.00 61.57 ? 607 ASN A HD21 1 ATOM 4617 H HD22 . ASN A 1 301 ? 25.104 219.215 -10.531 1.00 61.57 ? 607 ASN A HD22 1 ATOM 4618 N N . ASP A 1 302 ? 20.714 215.901 -13.182 1.00 35.70 ? 608 ASP A N 1 ATOM 4619 C CA . ASP A 1 302 ? 20.672 214.821 -14.157 1.00 41.47 ? 608 ASP A CA 1 ATOM 4620 C C . ASP A 1 302 ? 20.372 215.330 -15.561 1.00 39.58 ? 608 ASP A C 1 ATOM 4621 O O . ASP A 1 302 ? 20.741 214.665 -16.534 1.00 45.51 ? 608 ASP A O 1 ATOM 4622 C CB . ASP A 1 302 ? 19.629 213.776 -13.746 1.00 27.66 ? 608 ASP A CB 1 ATOM 4623 C CG . ASP A 1 302 ? 19.978 213.073 -12.432 1.00 35.18 ? 608 ASP A CG 1 ATOM 4624 O OD1 . ASP A 1 302 ? 20.947 212.282 -12.412 1.00 29.45 ? 608 ASP A OD1 1 ATOM 4625 O OD2 . ASP A 1 302 ? 19.273 213.308 -11.421 1.00 30.31 ? 608 ASP A OD2 1 ATOM 4626 H H . ASP A 1 302 ? 20.066 215.893 -12.616 1.00 42.84 ? 608 ASP A H 1 ATOM 4627 H HA . ASP A 1 302 ? 21.538 214.385 -14.177 1.00 49.76 ? 608 ASP A HA 1 ATOM 4628 H HB2 . ASP A 1 302 ? 18.771 214.213 -13.634 1.00 33.20 ? 608 ASP A HB2 1 ATOM 4629 H HB3 . ASP A 1 302 ? 19.569 213.100 -14.440 1.00 33.20 ? 608 ASP A HB3 1 ATOM 4630 N N . LEU A 1 303 ? 19.732 216.493 -15.685 1.00 41.93 ? 609 LEU A N 1 ATOM 4631 C CA . LEU A 1 303 ? 19.345 217.070 -16.967 1.00 52.80 ? 609 LEU A CA 1 ATOM 4632 C C . LEU A 1 303 ? 20.074 218.386 -17.220 1.00 51.69 ? 609 LEU A C 1 ATOM 4633 O O . LEU A 1 303 ? 20.415 219.121 -16.288 1.00 56.07 ? 609 LEU A O 1 ATOM 4634 C CB . LEU A 1 303 ? 17.831 217.332 -17.026 1.00 49.96 ? 609 LEU A CB 1 ATOM 4635 C CG . LEU A 1 303 ? 16.893 216.142 -16.794 1.00 49.50 ? 609 LEU A CG 1 ATOM 4636 C CD1 . LEU A 1 303 ? 15.447 216.617 -16.672 1.00 45.11 ? 609 LEU A CD1 1 ATOM 4637 C CD2 . LEU A 1 303 ? 17.004 215.151 -17.935 1.00 49.33 ? 609 LEU A CD2 1 ATOM 4638 H H . LEU A 1 303 ? 19.504 216.981 -15.014 1.00 50.32 ? 609 LEU A H 1 ATOM 4639 H HA . LEU A 1 303 ? 19.575 216.452 -17.679 1.00 63.36 ? 609 LEU A HA 1 ATOM 4640 H HB2 . LEU A 1 303 ? 17.616 217.997 -16.354 1.00 59.96 ? 609 LEU A HB2 1 ATOM 4641 H HB3 . LEU A 1 303 ? 17.623 217.689 -17.904 1.00 59.96 ? 609 LEU A HB3 1 ATOM 4642 H HG . LEU A 1 303 ? 17.139 215.692 -15.971 1.00 59.40 ? 609 LEU A HG 1 ATOM 4643 H HD11 . LEU A 1 303 ? 14.874 215.849 -16.526 1.00 54.13 ? 609 LEU A HD11 1 ATOM 4644 H HD12 . LEU A 1 303 ? 15.379 217.229 -15.922 1.00 54.13 ? 609 LEU A HD12 1 ATOM 4645 H HD13 . LEU A 1 303 ? 15.194 217.069 -17.492 1.00 54.13 ? 609 LEU A HD13 1 ATOM 4646 H HD21 . LEU A 1 303 ? 16.403 214.409 -17.767 1.00 59.20 ? 609 LEU A HD21 1 ATOM 4647 H HD22 . LEU A 1 303 ? 16.760 215.594 -18.762 1.00 59.20 ? 609 LEU A HD22 1 ATOM 4648 H HD23 . LEU A 1 303 ? 17.918 214.832 -17.987 1.00 59.20 ? 609 LEU A HD23 1 ATOM 4649 N N . LEU A 1 304 ? 20.307 218.677 -18.498 1.00 71.78 ? 610 LEU A N 1 ATOM 4650 C CA . LEU A 1 304 ? 20.704 220.014 -18.943 1.00 72.76 ? 610 LEU A CA 1 ATOM 4651 C C . LEU A 1 304 ? 19.440 220.864 -18.979 1.00 64.05 ? 610 LEU A C 1 ATOM 4652 O O . LEU A 1 304 ? 18.706 220.881 -19.966 1.00 73.21 ? 610 LEU A O 1 ATOM 4653 C CB . LEU A 1 304 ? 21.371 219.963 -20.316 1.00 78.52 ? 610 LEU A CB 1 ATOM 4654 C CG . LEU A 1 304 ? 22.621 219.094 -20.485 1.00 92.76 ? 610 LEU A CG 1 ATOM 4655 C CD1 . LEU A 1 304 ? 23.071 219.071 -21.949 1.00 76.87 ? 610 LEU A CD1 1 ATOM 4656 C CD2 . LEU A 1 304 ? 23.741 219.588 -19.577 1.00 92.08 ? 610 LEU A CD2 1 ATOM 4657 H H . LEU A 1 304 ? 20.240 218.107 -19.138 1.00 86.14 ? 610 LEU A H 1 ATOM 4658 H HA . LEU A 1 304 ? 21.325 220.402 -18.307 1.00 87.31 ? 610 LEU A HA 1 ATOM 4659 H HB2 . LEU A 1 304 ? 20.715 219.639 -20.953 1.00 94.23 ? 610 LEU A HB2 1 ATOM 4660 H HB3 . LEU A 1 304 ? 21.623 220.868 -20.557 1.00 94.23 ? 610 LEU A HB3 1 ATOM 4661 H HG . LEU A 1 304 ? 22.407 218.184 -20.225 1.00 111.32 ? 610 LEU A HG 1 ATOM 4662 H HD11 . LEU A 1 304 ? 23.862 218.515 -22.027 1.00 92.24 ? 610 LEU A HD11 1 ATOM 4663 H HD12 . LEU A 1 304 ? 22.356 218.707 -22.494 1.00 92.24 ? 610 LEU A HD12 1 ATOM 4664 H HD13 . LEU A 1 304 ? 23.274 219.977 -22.231 1.00 92.24 ? 610 LEU A HD13 1 ATOM 4665 H HD21 . LEU A 1 304 ? 24.520 219.023 -19.701 1.00 110.49 ? 610 LEU A HD21 1 ATOM 4666 H HD22 . LEU A 1 304 ? 23.956 220.504 -19.812 1.00 110.49 ? 610 LEU A HD22 1 ATOM 4667 H HD23 . LEU A 1 304 ? 23.443 219.543 -18.655 1.00 110.49 ? 610 LEU A HD23 1 ATOM 4668 N N . GLN A 1 305 ? 19.164 221.556 -17.887 1.00 57.68 ? 611 GLN A N 1 ATOM 4669 C CA . GLN A 1 305 ? 17.968 222.388 -17.825 1.00 75.45 ? 611 GLN A CA 1 ATOM 4670 C C . GLN A 1 305 ? 18.081 223.525 -18.836 1.00 73.99 ? 611 GLN A C 1 ATOM 4671 O O . GLN A 1 305 ? 18.889 224.438 -18.635 1.00 71.92 ? 611 GLN A O 1 ATOM 4672 C CB . GLN A 1 305 ? 17.767 222.961 -16.418 1.00 72.19 ? 611 GLN A CB 1 ATOM 4673 C CG . GLN A 1 305 ? 17.636 221.915 -15.300 1.00 72.08 ? 611 GLN A CG 1 ATOM 4674 C CD . GLN A 1 305 ? 16.406 221.017 -15.438 1.00 64.34 ? 611 GLN A CD 1 ATOM 4675 O OE1 . GLN A 1 305 ? 16.414 220.042 -16.189 1.00 71.64 ? 611 GLN A OE1 1 ATOM 4676 N NE2 . GLN A 1 305 ? 15.351 221.340 -14.702 1.00 50.03 ? 611 GLN A NE2 1 ATOM 4677 H H . GLN A 1 305 ? 19.645 221.565 -17.174 1.00 69.21 ? 611 GLN A H 1 ATOM 4678 H HA . GLN A 1 305 ? 17.191 221.853 -18.052 1.00 90.54 ? 611 GLN A HA 1 ATOM 4679 H HB2 . GLN A 1 305 ? 18.526 223.525 -16.203 1.00 86.63 ? 611 GLN A HB2 1 ATOM 4680 H HB3 . GLN A 1 305 ? 16.956 223.494 -16.415 1.00 86.63 ? 611 GLN A HB3 1 ATOM 4681 H HG2 . GLN A 1 305 ? 18.421 221.346 -15.312 1.00 86.50 ? 611 GLN A HG2 1 ATOM 4682 H HG3 . GLN A 1 305 ? 17.574 222.374 -14.448 1.00 86.50 ? 611 GLN A HG3 1 ATOM 4683 H HE21 . GLN A 1 305 ? 15.383 222.024 -14.181 1.00 60.04 ? 611 GLN A HE21 1 ATOM 4684 H HE22 . GLN A 1 305 ? 14.636 220.865 -14.744 1.00 60.04 ? 611 GLN A HE22 1 ATOM 4685 N N . PRO A 1 306 ? 17.302 223.519 -19.931 1.00 74.66 ? 612 PRO A N 1 ATOM 4686 C CA . PRO A 1 306 ? 17.356 224.660 -20.853 1.00 72.67 ? 612 PRO A CA 1 ATOM 4687 C C . PRO A 1 306 ? 16.707 225.880 -20.223 1.00 77.11 ? 612 PRO A C 1 ATOM 4688 O O . PRO A 1 306 ? 15.496 225.881 -19.971 1.00 75.22 ? 612 PRO A O 1 ATOM 4689 C CB . PRO A 1 306 ? 16.586 224.164 -22.082 1.00 70.46 ? 612 PRO A CB 1 ATOM 4690 C CG . PRO A 1 306 ? 15.605 223.194 -21.532 1.00 71.76 ? 612 PRO A CG 1 ATOM 4691 C CD . PRO A 1 306 ? 16.252 222.557 -20.319 1.00 78.95 ? 612 PRO A CD 1 ATOM 4692 H HA . PRO A 1 306 ? 18.273 224.863 -21.097 1.00 87.21 ? 612 PRO A HA 1 ATOM 4693 H HB2 . PRO A 1 306 ? 16.135 224.907 -22.510 1.00 84.56 ? 612 PRO A HB2 1 ATOM 4694 H HB3 . PRO A 1 306 ? 17.195 223.727 -22.698 1.00 84.56 ? 612 PRO A HB3 1 ATOM 4695 H HG2 . PRO A 1 306 ? 14.796 223.665 -21.276 1.00 86.12 ? 612 PRO A HG2 1 ATOM 4696 H HG3 . PRO A 1 306 ? 15.407 222.521 -22.202 1.00 86.12 ? 612 PRO A HG3 1 ATOM 4697 H HD2 . PRO A 1 306 ? 15.604 222.460 -19.603 1.00 94.75 ? 612 PRO A HD2 1 ATOM 4698 H HD3 . PRO A 1 306 ? 16.648 221.704 -20.557 1.00 94.75 ? 612 PRO A HD3 1 ATOM 4699 N N . ASN A 1 307 ? 17.496 226.915 -19.945 1.00 70.72 ? 613 ASN A N 1 ATOM 4700 C CA . ASN A 1 307 ? 16.974 228.064 -19.220 1.00 73.07 ? 613 ASN A CA 1 ATOM 4701 C C . ASN A 1 307 ? 15.993 228.831 -20.091 1.00 65.25 ? 613 ASN A C 1 ATOM 4702 O O . ASN A 1 307 ? 16.288 229.158 -21.244 1.00 61.28 ? 613 ASN A O 1 ATOM 4703 C CB . ASN A 1 307 ? 18.112 228.974 -18.774 1.00 67.08 ? 613 ASN A CB 1 ATOM 4704 C CG . ASN A 1 307 ? 18.957 228.347 -17.685 1.00 68.45 ? 613 ASN A CG 1 ATOM 4705 O OD1 . ASN A 1 307 ? 18.733 228.580 -16.486 1.00 55.25 ? 613 ASN A OD1 1 ATOM 4706 N ND2 . ASN A 1 307 ? 19.937 227.539 -18.094 1.00 58.18 ? 613 ASN A ND2 1 ATOM 4707 H H . ASN A 1 307 ? 18.326 226.974 -20.162 1.00 84.86 ? 613 ASN A H 1 ATOM 4708 H HA . ASN A 1 307 ? 16.503 227.757 -18.430 1.00 87.69 ? 613 ASN A HA 1 ATOM 4709 H HB2 . ASN A 1 307 ? 18.687 229.158 -19.533 1.00 80.50 ? 613 ASN A HB2 1 ATOM 4710 H HB3 . ASN A 1 307 ? 17.740 229.800 -18.429 1.00 80.50 ? 613 ASN A HB3 1 ATOM 4711 H HD21 . ASN A 1 307 ? 20.448 227.157 -17.517 1.00 69.81 ? 613 ASN A HD21 1 ATOM 4712 H HD22 . ASN A 1 307 ? 20.058 227.401 -18.934 1.00 69.81 ? 613 ASN A HD22 1 ATOM 4713 N N . THR A 1 308 ? 14.822 229.112 -19.533 1.00 58.30 ? 614 THR A N 1 ATOM 4714 C CA . THR A 1 308 ? 13.767 229.771 -20.276 1.00 65.05 ? 614 THR A CA 1 ATOM 4715 C C . THR A 1 308 ? 13.954 231.286 -20.227 1.00 60.81 ? 614 THR A C 1 ATOM 4716 O O . THR A 1 308 ? 14.859 231.816 -19.573 1.00 53.15 ? 614 THR A O 1 ATOM 4717 C CB . THR A 1 308 ? 12.404 229.369 -19.719 1.00 72.57 ? 614 THR A CB 1 ATOM 4718 O OG1 . THR A 1 308 ? 12.297 229.795 -18.352 1.00 75.47 ? 614 THR A OG1 1 ATOM 4719 C CG2 . THR A 1 308 ? 12.226 227.861 -19.798 1.00 66.73 ? 614 THR A CG2 1 ATOM 4720 H H . THR A 1 308 ? 14.616 228.927 -18.719 1.00 69.95 ? 614 THR A H 1 ATOM 4721 H HA . THR A 1 308 ? 13.808 229.492 -21.204 1.00 78.07 ? 614 THR A HA 1 ATOM 4722 H HB . THR A 1 308 ? 11.704 229.789 -20.243 1.00 87.09 ? 614 THR A HB 1 ATOM 4723 H HG1 . THR A 1 308 ? 12.900 229.435 -17.891 1.00 90.56 ? 614 THR A HG1 1 ATOM 4724 H HG21 . THR A 1 308 ? 11.359 227.611 -19.443 1.00 80.07 ? 614 THR A HG21 1 ATOM 4725 H HG22 . THR A 1 308 ? 12.285 227.569 -20.721 1.00 80.07 ? 614 THR A HG22 1 ATOM 4726 H HG23 . THR A 1 308 ? 12.918 227.418 -19.282 1.00 80.07 ? 614 THR A HG23 1 ATOM 4727 N N . GLU A 1 309 ? 13.070 231.992 -20.923 1.00 62.46 ? 615 GLU A N 1 ATOM 4728 C CA . GLU A 1 309 ? 13.132 233.440 -20.975 1.00 49.29 ? 615 GLU A CA 1 ATOM 4729 C C . GLU A 1 309 ? 12.733 234.029 -19.633 1.00 51.42 ? 615 GLU A C 1 ATOM 4730 O O . GLU A 1 309 ? 11.989 233.422 -18.853 1.00 53.42 ? 615 GLU A O 1 ATOM 4731 C CB . GLU A 1 309 ? 12.181 234.005 -22.031 1.00 54.52 ? 615 GLU A CB 1 ATOM 4732 C CG . GLU A 1 309 ? 11.975 233.179 -23.288 1.00 74.19 ? 615 GLU A CG 1 ATOM 4733 C CD . GLU A 1 309 ? 10.813 233.704 -24.121 1.00 83.77 ? 615 GLU A CD 1 ATOM 4734 O OE1 . GLU A 1 309 ? 10.621 234.943 -24.170 1.00 72.80 ? 615 GLU A OE1 1 ATOM 4735 O OE2 . GLU A 1 309 ? 10.088 232.875 -24.714 1.00 83.66 ? 615 GLU A OE2 1 ATOM 4736 H H . GLU A 1 309 ? 12.423 231.651 -21.374 1.00 74.95 ? 615 GLU A H 1 ATOM 4737 H HA . GLU A 1 309 ? 14.036 233.723 -21.184 1.00 59.15 ? 615 GLU A HA 1 ATOM 4738 H HB2 . GLU A 1 309 ? 11.310 234.121 -21.621 1.00 65.43 ? 615 GLU A HB2 1 ATOM 4739 H HB3 . GLU A 1 309 ? 12.521 234.869 -22.311 1.00 65.43 ? 615 GLU A HB3 1 ATOM 4740 H HG2 . GLU A 1 309 ? 12.779 233.216 -23.830 1.00 89.03 ? 615 GLU A HG2 1 ATOM 4741 H HG3 . GLU A 1 309 ? 11.780 232.262 -23.039 1.00 89.03 ? 615 GLU A HG3 1 ATOM 4742 N N . VAL A 1 310 ? 13.216 235.241 -19.371 1.00 41.39 ? 616 VAL A N 1 ATOM 4743 C CA . VAL A 1 310 ? 12.633 236.072 -18.329 1.00 39.44 ? 616 VAL A CA 1 ATOM 4744 C C . VAL A 1 310 ? 11.479 236.813 -18.993 1.00 37.66 ? 616 VAL A C 1 ATOM 4745 O O . VAL A 1 310 ? 11.673 237.821 -19.667 1.00 38.05 ? 616 VAL A O 1 ATOM 4746 C CB . VAL A 1 310 ? 13.647 237.027 -17.703 1.00 30.81 ? 616 VAL A CB 1 ATOM 4747 C CG1 . VAL A 1 310 ? 13.006 237.755 -16.539 1.00 29.76 ? 616 VAL A CG1 1 ATOM 4748 C CG2 . VAL A 1 310 ? 14.880 236.272 -17.234 1.00 31.97 ? 616 VAL A CG2 1 ATOM 4749 H H . VAL A 1 310 ? 13.879 235.602 -19.783 1.00 49.66 ? 616 VAL A H 1 ATOM 4750 H HA . VAL A 1 310 ? 12.272 235.506 -17.629 1.00 47.33 ? 616 VAL A HA 1 ATOM 4751 H HB . VAL A 1 310 ? 13.921 237.683 -18.362 1.00 36.97 ? 616 VAL A HB 1 ATOM 4752 H HG11 . VAL A 1 310 ? 13.658 238.358 -16.148 1.00 35.72 ? 616 VAL A HG11 1 ATOM 4753 H HG12 . VAL A 1 310 ? 12.242 238.257 -16.863 1.00 35.72 ? 616 VAL A HG12 1 ATOM 4754 H HG13 . VAL A 1 310 ? 12.720 237.104 -15.879 1.00 35.72 ? 616 VAL A HG13 1 ATOM 4755 H HG21 . VAL A 1 310 ? 15.505 236.901 -16.842 1.00 38.37 ? 616 VAL A HG21 1 ATOM 4756 H HG22 . VAL A 1 310 ? 14.614 235.613 -16.573 1.00 38.37 ? 616 VAL A HG22 1 ATOM 4757 H HG23 . VAL A 1 310 ? 15.288 235.831 -17.995 1.00 38.37 ? 616 VAL A HG23 1 ATOM 4758 N N . PHE A 1 311 ? 10.272 236.293 -18.822 1.00 41.90 ? 617 PHE A N 1 ATOM 4759 C CA . PHE A 1 311 ? 9.101 236.969 -19.356 1.00 44.08 ? 617 PHE A CA 1 ATOM 4760 C C . PHE A 1 311 ? 8.931 238.316 -18.673 1.00 39.65 ? 617 PHE A C 1 ATOM 4761 O O . PHE A 1 311 ? 8.838 238.389 -17.444 1.00 47.01 ? 617 PHE A O 1 ATOM 4762 C CB . PHE A 1 311 ? 7.863 236.097 -19.153 1.00 51.23 ? 617 PHE A CB 1 ATOM 4763 C CG . PHE A 1 311 ? 7.930 234.773 -19.863 1.00 52.37 ? 617 PHE A CG 1 ATOM 4764 C CD1 . PHE A 1 311 ? 7.849 234.705 -21.253 1.00 52.86 ? 617 PHE A CD1 1 ATOM 4765 C CD2 . PHE A 1 311 ? 8.071 233.594 -19.144 1.00 54.50 ? 617 PHE A CD2 1 ATOM 4766 C CE1 . PHE A 1 311 ? 7.906 233.484 -21.910 1.00 52.73 ? 617 PHE A CE1 1 ATOM 4767 C CE2 . PHE A 1 311 ? 8.130 232.366 -19.791 1.00 55.57 ? 617 PHE A CE2 1 ATOM 4768 C CZ . PHE A 1 311 ? 8.046 232.312 -21.179 1.00 57.50 ? 617 PHE A CZ 1 ATOM 4769 H H . PHE A 1 311 ? 10.106 235.560 -18.405 1.00 50.28 ? 617 PHE A H 1 ATOM 4770 H HA . PHE A 1 311 ? 9.220 237.118 -20.307 1.00 52.89 ? 617 PHE A HA 1 ATOM 4771 H HB2 . PHE A 1 311 ? 7.757 235.921 -18.205 1.00 61.47 ? 617 PHE A HB2 1 ATOM 4772 H HB3 . PHE A 1 311 ? 7.087 236.574 -19.487 1.00 61.47 ? 617 PHE A HB3 1 ATOM 4773 H HD1 . PHE A 1 311 ? 7.753 235.488 -21.746 1.00 63.44 ? 617 PHE A HD1 1 ATOM 4774 H HD2 . PHE A 1 311 ? 8.125 233.627 -18.216 1.00 65.40 ? 617 PHE A HD2 1 ATOM 4775 H HE1 . PHE A 1 311 ? 7.851 233.451 -22.838 1.00 63.28 ? 617 PHE A HE1 1 ATOM 4776 H HE2 . PHE A 1 311 ? 8.224 231.583 -19.298 1.00 66.69 ? 617 PHE A HE2 1 ATOM 4777 H HZ . PHE A 1 311 ? 8.087 231.492 -21.616 1.00 69.00 ? 617 PHE A HZ 1 ATOM 4778 N N . THR A 1 312 ? 8.909 239.382 -19.463 1.00 39.12 ? 618 THR A N 1 ATOM 4779 C CA . THR A 1 312 ? 8.793 240.737 -18.943 1.00 41.45 ? 618 THR A CA 1 ATOM 4780 C C . THR A 1 312 ? 7.393 241.283 -19.183 1.00 37.61 ? 618 THR A C 1 ATOM 4781 O O . THR A 1 312 ? 6.636 240.777 -20.016 1.00 41.21 ? 618 THR A O 1 ATOM 4782 C CB . THR A 1 312 ? 9.823 241.676 -19.593 1.00 42.67 ? 618 THR A CB 1 ATOM 4783 O OG1 . THR A 1 312 ? 9.584 241.747 -21.004 1.00 44.30 ? 618 THR A OG1 1 ATOM 4784 C CG2 . THR A 1 312 ? 11.258 241.195 -19.332 1.00 31.81 ? 618 THR A CG2 1 ATOM 4785 H H . THR A 1 312 ? 8.961 239.346 -20.321 1.00 46.94 ? 618 THR A H 1 ATOM 4786 H HA . THR A 1 312 ? 8.955 240.726 -17.986 1.00 49.74 ? 618 THR A HA 1 ATOM 4787 H HB . THR A 1 312 ? 9.729 242.563 -19.211 1.00 51.20 ? 618 THR A HB 1 ATOM 4788 H HG1 . THR A 1 312 ? 8.811 242.041 -21.150 1.00 53.16 ? 618 THR A HG1 1 ATOM 4789 H HG21 . THR A 1 312 ? 11.891 241.799 -19.749 1.00 38.17 ? 618 THR A HG21 1 ATOM 4790 H HG22 . THR A 1 312 ? 11.430 241.167 -18.378 1.00 38.17 ? 618 THR A HG22 1 ATOM 4791 H HG23 . THR A 1 312 ? 11.381 240.306 -19.701 1.00 38.17 ? 618 THR A HG23 1 ATOM 4792 N N . ASP A 1 313 ? 7.062 242.334 -18.431 1.00 37.54 ? 619 ASP A N 1 ATOM 4793 C CA . ASP A 1 313 ? 5.872 243.152 -18.674 1.00 47.19 ? 619 ASP A CA 1 ATOM 4794 C C . ASP A 1 313 ? 4.581 242.399 -18.380 1.00 48.49 ? 619 ASP A C 1 ATOM 4795 O O . ASP A 1 313 ? 3.528 242.718 -18.942 1.00 47.14 ? 619 ASP A O 1 ATOM 4796 C CB . ASP A 1 313 ? 5.850 243.682 -20.116 1.00 48.49 ? 619 ASP A CB 1 ATOM 4797 C CG . ASP A 1 313 ? 7.076 244.521 -20.448 1.00 55.62 ? 619 ASP A CG 1 ATOM 4798 O OD1 . ASP A 1 313 ? 7.343 245.508 -19.715 1.00 47.84 ? 619 ASP A OD1 1 ATOM 4799 O OD2 . ASP A 1 313 ? 7.774 244.176 -21.431 1.00 53.45 ? 619 ASP A OD2 1 ATOM 4800 H H . ASP A 1 313 ? 7.524 242.600 -17.757 1.00 45.05 ? 619 ASP A H 1 ATOM 4801 H HA . ASP A 1 313 ? 5.902 243.920 -18.083 1.00 56.63 ? 619 ASP A HA 1 ATOM 4802 H HB2 . ASP A 1 313 ? 5.825 242.930 -20.729 1.00 58.18 ? 619 ASP A HB2 1 ATOM 4803 H HB3 . ASP A 1 313 ? 5.064 244.237 -20.237 1.00 58.18 ? 619 ASP A HB3 1 ATOM 4804 N N . VAL A 1 314 ? 4.643 241.411 -17.493 1.00 34.50 ? 620 VAL A N 1 ATOM 4805 C CA . VAL A 1 314 ? 3.486 240.572 -17.217 1.00 43.99 ? 620 VAL A CA 1 ATOM 4806 C C . VAL A 1 314 ? 3.662 239.949 -15.834 1.00 40.94 ? 620 VAL A C 1 ATOM 4807 O O . VAL A 1 314 ? 4.750 239.488 -15.479 1.00 37.31 ? 620 VAL A O 1 ATOM 4808 C CB . VAL A 1 314 ? 3.315 239.511 -18.332 1.00 42.24 ? 620 VAL A CB 1 ATOM 4809 C CG1 . VAL A 1 314 ? 4.555 238.644 -18.450 1.00 42.12 ? 620 VAL A CG1 1 ATOM 4810 C CG2 . VAL A 1 314 ? 2.107 238.672 -18.075 1.00 51.40 ? 620 VAL A CG2 1 ATOM 4811 H H . VAL A 1 314 ? 5.343 241.206 -17.039 1.00 41.41 ? 620 VAL A H 1 ATOM 4812 H HA . VAL A 1 314 ? 2.689 241.125 -17.200 1.00 52.78 ? 620 VAL A HA 1 ATOM 4813 H HB . VAL A 1 314 ? 3.187 239.965 -19.180 1.00 50.69 ? 620 VAL A HB 1 ATOM 4814 H HG11 . VAL A 1 314 ? 4.417 237.992 -19.154 1.00 50.54 ? 620 VAL A HG11 1 ATOM 4815 H HG12 . VAL A 1 314 ? 5.314 239.208 -18.664 1.00 50.54 ? 620 VAL A HG12 1 ATOM 4816 H HG13 . VAL A 1 314 ? 4.705 238.193 -17.605 1.00 50.54 ? 620 VAL A HG13 1 ATOM 4817 H HG21 . VAL A 1 314 ? 2.021 238.016 -18.785 1.00 61.68 ? 620 VAL A HG21 1 ATOM 4818 H HG22 . VAL A 1 314 ? 2.210 238.223 -17.221 1.00 61.68 ? 620 VAL A HG22 1 ATOM 4819 H HG23 . VAL A 1 314 ? 1.324 239.244 -18.056 1.00 61.68 ? 620 VAL A HG23 1 ATOM 4820 N N . CYS A 1 315 ? 2.582 239.946 -15.053 1.00 36.38 ? 621 CYS A N 1 ATOM 4821 C CA . CYS A 1 315 ? 2.622 239.330 -13.735 1.00 44.80 ? 621 CYS A CA 1 ATOM 4822 C C . CYS A 1 315 ? 2.973 237.852 -13.854 1.00 43.75 ? 621 CYS A C 1 ATOM 4823 O O . CYS A 1 315 ? 2.317 237.096 -14.576 1.00 37.09 ? 621 CYS A O 1 ATOM 4824 C CB . CYS A 1 315 ? 1.282 239.485 -13.029 1.00 45.10 ? 621 CYS A CB 1 ATOM 4825 S SG . CYS A 1 315 ? 1.229 238.687 -11.401 1.00 58.25 ? 621 CYS A SG 1 ATOM 4826 H H . CYS A 1 315 ? 1.823 240.292 -15.263 1.00 43.65 ? 621 CYS A H 1 ATOM 4827 H HA . CYS A 1 315 ? 3.303 239.764 -13.197 1.00 53.76 ? 621 CYS A HA 1 ATOM 4828 H HB2 . CYS A 1 315 ? 1.100 240.430 -12.904 1.00 54.12 ? 621 CYS A HB2 1 ATOM 4829 H HB3 . CYS A 1 315 ? 0.590 239.086 -13.579 1.00 54.12 ? 621 CYS A HB3 1 ATOM 4830 N N . VAL A 1 316 ? 4.000 237.443 -13.124 1.00 39.24 ? 622 VAL A N 1 ATOM 4831 C CA . VAL A 1 316 ? 4.606 236.131 -13.283 1.00 39.92 ? 622 VAL A CA 1 ATOM 4832 C C . VAL A 1 316 ? 4.985 235.615 -11.903 1.00 42.44 ? 622 VAL A C 1 ATOM 4833 O O . VAL A 1 316 ? 5.452 236.378 -11.051 1.00 41.13 ? 622 VAL A O 1 ATOM 4834 C CB . VAL A 1 316 ? 5.831 236.213 -14.219 1.00 40.13 ? 622 VAL A CB 1 ATOM 4835 C CG1 . VAL A 1 316 ? 6.730 235.024 -14.062 1.00 50.25 ? 622 VAL A CG1 1 ATOM 4836 C CG2 . VAL A 1 316 ? 5.377 236.288 -15.642 1.00 50.15 ? 622 VAL A CG2 1 ATOM 4837 H H . VAL A 1 316 ? 4.374 237.921 -12.515 1.00 47.09 ? 622 VAL A H 1 ATOM 4838 H HA . VAL A 1 316 ? 3.961 235.521 -13.673 1.00 47.91 ? 622 VAL A HA 1 ATOM 4839 H HB . VAL A 1 316 ? 6.341 237.013 -14.016 1.00 48.16 ? 622 VAL A HB 1 ATOM 4840 H HG11 . VAL A 1 316 ? 7.483 235.117 -14.666 1.00 60.30 ? 622 VAL A HG11 1 ATOM 4841 H HG12 . VAL A 1 316 ? 7.043 234.984 -13.145 1.00 60.30 ? 622 VAL A HG12 1 ATOM 4842 H HG13 . VAL A 1 316 ? 6.230 234.221 -14.277 1.00 60.30 ? 622 VAL A HG13 1 ATOM 4843 H HG21 . VAL A 1 316 ? 6.156 236.339 -16.219 1.00 60.18 ? 622 VAL A HG21 1 ATOM 4844 H HG22 . VAL A 1 316 ? 4.862 235.494 -15.851 1.00 60.18 ? 622 VAL A HG22 1 ATOM 4845 H HG23 . VAL A 1 316 ? 4.828 237.079 -15.756 1.00 60.18 ? 622 VAL A HG23 1 ATOM 4846 N N . ASP A 1 317 ? 4.756 234.328 -11.673 1.00 33.03 ? 623 ASP A N 1 ATOM 4847 C CA . ASP A 1 317 ? 5.290 233.676 -10.488 1.00 42.68 ? 623 ASP A CA 1 ATOM 4848 C C . ASP A 1 317 ? 6.735 233.280 -10.755 1.00 31.20 ? 623 ASP A C 1 ATOM 4849 O O . ASP A 1 317 ? 7.080 232.834 -11.852 1.00 34.34 ? 623 ASP A O 1 ATOM 4850 C CB . ASP A 1 317 ? 4.457 232.448 -10.122 1.00 36.93 ? 623 ASP A CB 1 ATOM 4851 C CG . ASP A 1 317 ? 4.303 231.502 -11.277 1.00 51.98 ? 623 ASP A CG 1 ATOM 4852 O OD1 . ASP A 1 317 ? 3.472 231.796 -12.169 1.00 63.51 ? 623 ASP A OD1 1 ATOM 4853 O OD2 . ASP A 1 317 ? 5.026 230.482 -11.308 1.00 53.49 ? 623 ASP A OD2 1 ATOM 4854 H H . ASP A 1 317 ? 4.297 233.812 -12.186 1.00 39.63 ? 623 ASP A H 1 ATOM 4855 H HA . ASP A 1 317 ? 5.272 234.295 -9.741 1.00 51.21 ? 623 ASP A HA 1 ATOM 4856 H HB2 . ASP A 1 317 ? 4.893 231.972 -9.398 1.00 44.31 ? 623 ASP A HB2 1 ATOM 4857 H HB3 . ASP A 1 317 ? 3.572 232.735 -9.847 1.00 44.31 ? 623 ASP A HB3 1 ATOM 4858 N N . TYR A 1 318 ? 7.587 233.461 -9.754 1.00 26.96 ? 624 TYR A N 1 ATOM 4859 C CA . TYR A 1 318 ? 9.009 233.233 -9.935 1.00 31.74 ? 624 TYR A CA 1 ATOM 4860 C C . TYR A 1 318 ? 9.569 232.464 -8.749 1.00 26.42 ? 624 TYR A C 1 ATOM 4861 O O . TYR A 1 318 ? 8.988 232.437 -7.662 1.00 28.19 ? 624 TYR A O 1 ATOM 4862 C CB . TYR A 1 318 ? 9.775 234.561 -10.117 1.00 29.79 ? 624 TYR A CB 1 ATOM 4863 C CG . TYR A 1 318 ? 9.719 235.509 -8.929 1.00 27.12 ? 624 TYR A CG 1 ATOM 4864 C CD1 . TYR A 1 318 ? 10.511 235.305 -7.811 1.00 27.30 ? 624 TYR A CD1 1 ATOM 4865 C CD2 . TYR A 1 318 ? 8.889 236.620 -8.947 1.00 29.52 ? 624 TYR A CD2 1 ATOM 4866 C CE1 . TYR A 1 318 ? 10.464 236.174 -6.737 1.00 37.15 ? 624 TYR A CE1 1 ATOM 4867 C CE2 . TYR A 1 318 ? 8.840 237.487 -7.891 1.00 33.30 ? 624 TYR A CE2 1 ATOM 4868 C CZ . TYR A 1 318 ? 9.622 237.266 -6.796 1.00 31.28 ? 624 TYR A CZ 1 ATOM 4869 O OH . TYR A 1 318 ? 9.548 238.148 -5.770 1.00 29.31 ? 624 TYR A OH 1 ATOM 4870 H H . TYR A 1 318 ? 7.365 233.714 -8.962 1.00 32.35 ? 624 TYR A H 1 ATOM 4871 H HA . TYR A 1 318 ? 9.144 232.697 -10.732 1.00 38.09 ? 624 TYR A HA 1 ATOM 4872 H HB2 . TYR A 1 318 ? 10.709 234.357 -10.284 1.00 35.75 ? 624 TYR A HB2 1 ATOM 4873 H HB3 . TYR A 1 318 ? 9.403 235.029 -10.881 1.00 35.75 ? 624 TYR A HB3 1 ATOM 4874 H HD1 . TYR A 1 318 ? 11.077 234.567 -7.779 1.00 32.76 ? 624 TYR A HD1 1 ATOM 4875 H HD2 . TYR A 1 318 ? 8.355 236.777 -9.691 1.00 35.43 ? 624 TYR A HD2 1 ATOM 4876 H HE1 . TYR A 1 318 ? 10.997 236.029 -5.989 1.00 44.58 ? 624 TYR A HE1 1 ATOM 4877 H HE2 . TYR A 1 318 ? 8.275 238.225 -7.920 1.00 39.96 ? 624 TYR A HE2 1 ATOM 4878 H HH . TYR A 1 318 ? 10.068 237.916 -5.153 1.00 35.18 ? 624 TYR A HH 1 ATOM 4879 N N . ASP A 1 319 ? 10.725 231.848 -8.983 1.00 27.12 ? 625 ASP A N 1 ATOM 4880 C CA . ASP A 1 319 ? 11.474 231.125 -7.958 1.00 33.66 ? 625 ASP A CA 1 ATOM 4881 C C . ASP A 1 319 ? 12.943 231.421 -8.246 1.00 26.46 ? 625 ASP A C 1 ATOM 4882 O O . ASP A 1 319 ? 13.566 230.748 -9.071 1.00 29.18 ? 625 ASP A O 1 ATOM 4883 C CB . ASP A 1 319 ? 11.168 229.626 -7.993 1.00 33.00 ? 625 ASP A CB 1 ATOM 4884 C CG . ASP A 1 319 ? 11.805 228.863 -6.838 1.00 36.46 ? 625 ASP A CG 1 ATOM 4885 O OD1 . ASP A 1 319 ? 12.890 229.271 -6.371 1.00 35.98 ? 625 ASP A OD1 1 ATOM 4886 O OD2 . ASP A 1 319 ? 11.216 227.849 -6.400 1.00 38.38 ? 625 ASP A OD2 1 ATOM 4887 H H . ASP A 1 319 ? 11.107 231.835 -9.753 1.00 32.55 ? 625 ASP A H 1 ATOM 4888 H HA . ASP A 1 319 ? 11.250 231.470 -7.080 1.00 40.39 ? 625 ASP A HA 1 ATOM 4889 H HB2 . ASP A 1 319 ? 10.208 229.499 -7.942 1.00 39.60 ? 625 ASP A HB2 1 ATOM 4890 H HB3 . ASP A 1 319 ? 11.509 229.253 -8.821 1.00 39.60 ? 625 ASP A HB3 1 ATOM 4891 N N . LEU A 1 320 ? 13.490 232.422 -7.559 1.00 30.65 ? 626 LEU A N 1 ATOM 4892 C CA . LEU A 1 320 ? 14.785 233.003 -7.903 1.00 37.52 ? 626 LEU A CA 1 ATOM 4893 C C . LEU A 1 320 ? 15.779 232.721 -6.786 1.00 31.99 ? 626 LEU A C 1 ATOM 4894 O O . LEU A 1 320 ? 15.665 233.281 -5.689 1.00 28.10 ? 626 LEU A O 1 ATOM 4895 C CB . LEU A 1 320 ? 14.663 234.509 -8.153 1.00 28.63 ? 626 LEU A CB 1 ATOM 4896 C CG . LEU A 1 320 ? 13.772 234.968 -9.313 1.00 36.36 ? 626 LEU A CG 1 ATOM 4897 C CD1 . LEU A 1 320 ? 13.763 236.514 -9.468 1.00 31.23 ? 626 LEU A CD1 1 ATOM 4898 C CD2 . LEU A 1 320 ? 14.203 234.328 -10.619 1.00 33.60 ? 626 LEU A CD2 1 ATOM 4899 H H . LEU A 1 320 ? 13.121 232.789 -6.875 1.00 36.78 ? 626 LEU A H 1 ATOM 4900 H HA . LEU A 1 320 ? 15.116 232.587 -8.715 1.00 45.02 ? 626 LEU A HA 1 ATOM 4901 H HB2 . LEU A 1 320 ? 14.312 234.919 -7.346 1.00 34.36 ? 626 LEU A HB2 1 ATOM 4902 H HB3 . LEU A 1 320 ? 15.552 234.857 -8.324 1.00 34.36 ? 626 LEU A HB3 1 ATOM 4903 H HG . LEU A 1 320 ? 12.861 234.686 -9.134 1.00 43.63 ? 626 LEU A HG 1 ATOM 4904 H HD11 . LEU A 1 320 ? 13.188 236.753 -10.212 1.00 37.48 ? 626 LEU A HD11 1 ATOM 4905 H HD12 . LEU A 1 320 ? 13.429 236.912 -8.649 1.00 37.48 ? 626 LEU A HD12 1 ATOM 4906 H HD13 . LEU A 1 320 ? 14.668 236.819 -9.639 1.00 37.48 ? 626 LEU A HD13 1 ATOM 4907 H HD21 . LEU A 1 320 ? 13.620 234.638 -11.330 1.00 40.32 ? 626 LEU A HD21 1 ATOM 4908 H HD22 . LEU A 1 320 ? 15.120 234.582 -10.807 1.00 40.32 ? 626 LEU A HD22 1 ATOM 4909 H HD23 . LEU A 1 320 ? 14.138 233.364 -10.534 1.00 40.32 ? 626 LEU A HD23 1 ATOM 4910 N N . TYR A 1 321 ? 16.770 231.883 -7.089 1.00 29.67 ? 627 TYR A N 1 ATOM 4911 C CA . TYR A 1 321 ? 17.848 231.550 -6.160 1.00 29.88 ? 627 TYR A CA 1 ATOM 4912 C C . TYR A 1 321 ? 17.282 231.148 -4.803 1.00 34.78 ? 627 TYR A C 1 ATOM 4913 O O . TYR A 1 321 ? 17.761 231.577 -3.751 1.00 34.21 ? 627 TYR A O 1 ATOM 4914 C CB . TYR A 1 321 ? 18.835 232.715 -6.042 1.00 32.42 ? 627 TYR A CB 1 ATOM 4915 C CG . TYR A 1 321 ? 19.272 233.235 -7.399 1.00 32.49 ? 627 TYR A CG 1 ATOM 4916 C CD1 . TYR A 1 321 ? 20.016 232.436 -8.260 1.00 32.59 ? 627 TYR A CD1 1 ATOM 4917 C CD2 . TYR A 1 321 ? 18.920 234.507 -7.831 1.00 34.53 ? 627 TYR A CD2 1 ATOM 4918 C CE1 . TYR A 1 321 ? 20.403 232.884 -9.501 1.00 37.98 ? 627 TYR A CE1 1 ATOM 4919 C CE2 . TYR A 1 321 ? 19.308 234.972 -9.075 1.00 33.67 ? 627 TYR A CE2 1 ATOM 4920 C CZ . TYR A 1 321 ? 20.052 234.157 -9.908 1.00 36.51 ? 627 TYR A CZ 1 ATOM 4921 O OH . TYR A 1 321 ? 20.441 234.594 -11.158 1.00 41.31 ? 627 TYR A OH 1 ATOM 4922 H H . TYR A 1 321 ? 16.840 231.484 -7.848 1.00 35.60 ? 627 TYR A H 1 ATOM 4923 H HA . TYR A 1 321 ? 18.334 230.788 -6.511 1.00 35.85 ? 627 TYR A HA 1 ATOM 4924 H HB2 . TYR A 1 321 ? 18.411 233.444 -5.563 1.00 38.90 ? 627 TYR A HB2 1 ATOM 4925 H HB3 . TYR A 1 321 ? 19.625 232.416 -5.565 1.00 38.90 ? 627 TYR A HB3 1 ATOM 4926 H HD1 . TYR A 1 321 ? 20.255 231.578 -7.991 1.00 39.11 ? 627 TYR A HD1 1 ATOM 4927 H HD2 . TYR A 1 321 ? 18.419 235.058 -7.273 1.00 41.44 ? 627 TYR A HD2 1 ATOM 4928 H HE1 . TYR A 1 321 ? 20.904 232.335 -10.061 1.00 45.58 ? 627 TYR A HE1 1 ATOM 4929 H HE2 . TYR A 1 321 ? 19.067 235.827 -9.351 1.00 40.41 ? 627 TYR A HE2 1 ATOM 4930 H HH . TYR A 1 321 ? 20.169 235.378 -11.285 1.00 49.57 ? 627 TYR A HH 1 ATOM 4931 N N . GLY A 1 322 ? 16.225 230.332 -4.837 1.00 27.18 ? 628 GLY A N 1 ATOM 4932 C CA . GLY A 1 322 ? 15.582 229.841 -3.641 1.00 38.49 ? 628 GLY A CA 1 ATOM 4933 C C . GLY A 1 322 ? 14.376 230.634 -3.173 1.00 36.62 ? 628 GLY A C 1 ATOM 4934 O O . GLY A 1 322 ? 13.581 230.109 -2.382 1.00 36.67 ? 628 GLY A O 1 ATOM 4935 H H . GLY A 1 322 ? 15.863 230.048 -5.563 1.00 32.62 ? 628 GLY A H 1 ATOM 4936 H HA2 . GLY A 1 322 ? 15.294 228.927 -3.794 1.00 46.18 ? 628 GLY A HA2 1 ATOM 4937 H HA3 . GLY A 1 322 ? 16.230 229.833 -2.919 1.00 46.18 ? 628 GLY A HA3 1 ATOM 4938 N N . ILE A 1 323 ? 14.218 231.875 -3.630 1.00 33.85 ? 629 ILE A N 1 ATOM 4939 C CA . ILE A 1 323 ? 13.195 232.790 -3.125 1.00 35.34 ? 629 ILE A CA 1 ATOM 4940 C C . ILE A 1 323 ? 12.033 232.853 -4.109 1.00 39.22 ? 629 ILE A C 1 ATOM 4941 O O . ILE A 1 323 ? 12.233 233.102 -5.306 1.00 33.43 ? 629 ILE A O 1 ATOM 4942 C CB . ILE A 1 323 ? 13.767 234.196 -2.902 1.00 39.97 ? 629 ILE A CB 1 ATOM 4943 C CG1 . ILE A 1 323 ? 15.119 234.126 -2.177 1.00 41.00 ? 629 ILE A CG1 1 ATOM 4944 C CG2 . ILE A 1 323 ? 12.751 235.043 -2.136 1.00 37.19 ? 629 ILE A CG2 1 ATOM 4945 C CD1 . ILE A 1 323 ? 15.043 233.557 -0.777 1.00 33.30 ? 629 ILE A CD1 1 ATOM 4946 H H . ILE A 1 323 ? 14.704 232.219 -4.250 1.00 40.62 ? 629 ILE A H 1 ATOM 4947 H HA . ILE A 1 323 ? 12.859 232.459 -2.278 1.00 42.41 ? 629 ILE A HA 1 ATOM 4948 H HB . ILE A 1 323 ? 13.910 234.606 -3.770 1.00 47.97 ? 629 ILE A HB 1 ATOM 4949 H HG12 . ILE A 1 323 ? 15.720 233.564 -2.691 1.00 49.20 ? 629 ILE A HG12 1 ATOM 4950 H HG13 . ILE A 1 323 ? 15.484 235.022 -2.111 1.00 49.20 ? 629 ILE A HG13 1 ATOM 4951 H HG21 . ILE A 1 323 ? 13.119 235.929 -1.998 1.00 44.62 ? 629 ILE A HG21 1 ATOM 4952 H HG22 . ILE A 1 323 ? 11.933 235.100 -2.655 1.00 44.62 ? 629 ILE A HG22 1 ATOM 4953 H HG23 . ILE A 1 323 ? 12.571 234.622 -1.280 1.00 44.62 ? 629 ILE A HG23 1 ATOM 4954 H HD11 . ILE A 1 323 ? 15.933 233.548 -0.392 1.00 39.96 ? 629 ILE A HD11 1 ATOM 4955 H HD12 . ILE A 1 323 ? 14.456 234.114 -0.242 1.00 39.96 ? 629 ILE A HD12 1 ATOM 4956 H HD13 . ILE A 1 323 ? 14.692 232.654 -0.823 1.00 39.96 ? 629 ILE A HD13 1 ATOM 4957 N N . THR A 1 324 ? 10.817 232.683 -3.599 1.00 32.36 ? 630 THR A N 1 ATOM 4958 C CA . THR A 1 324 ? 9.626 232.615 -4.431 1.00 33.91 ? 630 THR A CA 1 ATOM 4959 C C . THR A 1 324 ? 8.802 233.882 -4.279 1.00 34.66 ? 630 THR A C 1 ATOM 4960 O O . THR A 1 324 ? 8.979 234.665 -3.342 1.00 33.77 ? 630 THR A O 1 ATOM 4961 C CB . THR A 1 324 ? 8.753 231.400 -4.081 1.00 37.52 ? 630 THR A CB 1 ATOM 4962 O OG1 . THR A 1 324 ? 8.415 231.424 -2.689 1.00 39.09 ? 630 THR A OG1 1 ATOM 4963 C CG2 . THR A 1 324 ? 9.475 230.123 -4.404 1.00 29.92 ? 630 THR A CG2 1 ATOM 4964 H H . THR A 1 324 ? 10.655 232.603 -2.758 1.00 38.83 ? 630 THR A H 1 ATOM 4965 H HA . THR A 1 324 ? 9.892 232.538 -5.360 1.00 40.70 ? 630 THR A HA 1 ATOM 4966 H HB . THR A 1 324 ? 7.939 231.429 -4.608 1.00 45.03 ? 630 THR A HB 1 ATOM 4967 H HG1 . THR A 1 324 ? 7.938 230.759 -2.498 1.00 46.91 ? 630 THR A HG1 1 ATOM 4968 H HG21 . THR A 1 324 ? 8.917 229.362 -4.180 1.00 35.90 ? 630 THR A HG21 1 ATOM 4969 H HG22 . THR A 1 324 ? 9.686 230.092 -5.350 1.00 35.90 ? 630 THR A HG22 1 ATOM 4970 H HG23 . THR A 1 324 ? 10.299 230.071 -3.894 1.00 35.90 ? 630 THR A HG23 1 ATOM 4971 N N . GLY A 1 325 ? 7.903 234.071 -5.230 1.00 36.65 ? 631 GLY A N 1 ATOM 4972 C CA . GLY A 1 325 ? 7.055 235.243 -5.250 1.00 32.58 ? 631 GLY A CA 1 ATOM 4973 C C . GLY A 1 325 ? 6.425 235.396 -6.614 1.00 32.06 ? 631 GLY A C 1 ATOM 4974 O O . GLY A 1 325 ? 6.573 234.545 -7.498 1.00 30.96 ? 631 GLY A O 1 ATOM 4975 H H . GLY A 1 325 ? 7.764 233.527 -5.881 1.00 43.98 ? 631 GLY A H 1 ATOM 4976 H HA2 . GLY A 1 325 ? 6.353 235.156 -4.586 1.00 39.10 ? 631 GLY A HA2 1 ATOM 4977 H HA3 . GLY A 1 325 ? 7.579 236.035 -5.053 1.00 39.10 ? 631 GLY A HA3 1 ATOM 4978 N N . GLN A 1 326 ? 5.711 236.508 -6.766 1.00 32.68 ? 632 GLN A N 1 ATOM 4979 C CA . GLN A 1 326 ? 5.148 236.889 -8.050 1.00 40.07 ? 632 GLN A CA 1 ATOM 4980 C C . GLN A 1 326 ? 5.357 238.378 -8.273 1.00 41.56 ? 632 GLN A C 1 ATOM 4981 O O . GLN A 1 326 ? 5.324 239.172 -7.325 1.00 36.53 ? 632 GLN A O 1 ATOM 4982 C CB . GLN A 1 326 ? 3.659 236.537 -8.145 1.00 48.03 ? 632 GLN A CB 1 ATOM 4983 C CG . GLN A 1 326 ? 2.784 237.185 -7.098 1.00 57.17 ? 632 GLN A CG 1 ATOM 4984 C CD . GLN A 1 326 ? 1.330 236.778 -7.237 1.00 74.11 ? 632 GLN A CD 1 ATOM 4985 O OE1 . GLN A 1 326 ? 1.017 235.720 -7.795 1.00 71.62 ? 632 GLN A OE1 1 ATOM 4986 N NE2 . GLN A 1 326 ? 0.431 237.622 -6.739 1.00 81.45 ? 632 GLN A NE2 1 ATOM 4987 H H . GLN A 1 326 ? 5.538 237.063 -6.131 1.00 39.22 ? 632 GLN A H 1 ATOM 4988 H HA . GLN A 1 326 ? 5.615 236.412 -8.753 1.00 48.09 ? 632 GLN A HA 1 ATOM 4989 H HB2 . GLN A 1 326 ? 3.331 236.815 -9.014 1.00 57.63 ? 632 GLN A HB2 1 ATOM 4990 H HB3 . GLN A 1 326 ? 3.563 235.576 -8.053 1.00 57.63 ? 632 GLN A HB3 1 ATOM 4991 H HG2 . GLN A 1 326 ? 3.089 236.916 -6.217 1.00 68.60 ? 632 GLN A HG2 1 ATOM 4992 H HG3 . GLN A 1 326 ? 2.838 238.149 -7.190 1.00 68.60 ? 632 GLN A HG3 1 ATOM 4993 H HE21 . GLN A 1 326 ? 0.688 238.351 -6.364 1.00 97.74 ? 632 GLN A HE21 1 ATOM 4994 H HE22 . GLN A 1 326 ? -0.407 237.438 -6.793 1.00 97.74 ? 632 GLN A HE22 1 ATOM 4995 N N . GLY A 1 327 ? 5.582 238.747 -9.532 1.00 37.41 ? 633 GLY A N 1 ATOM 4996 C CA . GLY A 1 327 ? 5.794 240.139 -9.874 1.00 38.90 ? 633 GLY A CA 1 ATOM 4997 C C . GLY A 1 327 ? 5.915 240.321 -11.371 1.00 40.10 ? 633 GLY A C 1 ATOM 4998 O O . GLY A 1 327 ? 5.885 239.362 -12.149 1.00 35.42 ? 633 GLY A O 1 ATOM 4999 H H . GLY A 1 327 ? 5.616 238.207 -10.202 1.00 44.89 ? 633 GLY A H 1 ATOM 5000 H HA2 . GLY A 1 327 ? 5.049 240.672 -9.555 1.00 46.68 ? 633 GLY A HA2 1 ATOM 5001 H HA3 . GLY A 1 327 ? 6.608 240.459 -9.455 1.00 46.68 ? 633 GLY A HA3 1 ATOM 5002 N N . ILE A 1 328 ? 6.044 241.586 -11.760 1.00 38.59 ? 634 ILE A N 1 ATOM 5003 C CA . ILE A 1 328 ? 6.217 241.988 -13.151 1.00 37.51 ? 634 ILE A CA 1 ATOM 5004 C C . ILE A 1 328 ? 7.681 242.359 -13.341 1.00 38.74 ? 634 ILE A C 1 ATOM 5005 O O . ILE A 1 328 ? 8.188 243.283 -12.687 1.00 36.46 ? 634 ILE A O 1 ATOM 5006 C CB . ILE A 1 328 ? 5.301 243.169 -13.516 1.00 38.56 ? 634 ILE A CB 1 ATOM 5007 C CG1 . ILE A 1 328 ? 3.832 242.782 -13.347 1.00 40.88 ? 634 ILE A CG1 1 ATOM 5008 C CG2 . ILE A 1 328 ? 5.565 243.638 -14.953 1.00 38.11 ? 634 ILE A CG2 1 ATOM 5009 C CD1 . ILE A 1 328 ? 2.899 243.971 -13.298 1.00 34.69 ? 634 ILE A CD1 1 ATOM 5010 H H . ILE A 1 328 ? 6.034 242.251 -11.215 1.00 46.30 ? 634 ILE A H 1 ATOM 5011 H HA . ILE A 1 328 ? 6.008 241.242 -13.735 1.00 45.02 ? 634 ILE A HA 1 ATOM 5012 H HB . ILE A 1 328 ? 5.495 243.905 -12.913 1.00 46.28 ? 634 ILE A HB 1 ATOM 5013 H HG12 . ILE A 1 328 ? 3.566 242.226 -14.097 1.00 49.06 ? 634 ILE A HG12 1 ATOM 5014 H HG13 . ILE A 1 328 ? 3.730 242.289 -12.518 1.00 49.06 ? 634 ILE A HG13 1 ATOM 5015 H HG21 . ILE A 1 328 ? 4.976 244.381 -15.156 1.00 45.74 ? 634 ILE A HG21 1 ATOM 5016 H HG22 . ILE A 1 328 ? 6.490 243.919 -15.028 1.00 45.74 ? 634 ILE A HG22 1 ATOM 5017 H HG23 . ILE A 1 328 ? 5.392 242.902 -15.561 1.00 45.74 ? 634 ILE A HG23 1 ATOM 5018 H HD11 . ILE A 1 328 ? 1.989 243.654 -13.191 1.00 41.63 ? 634 ILE A HD11 1 ATOM 5019 H HD12 . ILE A 1 328 ? 3.144 244.534 -12.547 1.00 41.63 ? 634 ILE A HD12 1 ATOM 5020 H HD13 . ILE A 1 328 ? 2.980 244.470 -14.126 1.00 41.63 ? 634 ILE A HD13 1 ATOM 5021 N N . PHE A 1 329 ? 8.359 241.646 -14.235 1.00 31.28 ? 635 PHE A N 1 ATOM 5022 C CA . PHE A 1 329 ? 9.757 241.913 -14.534 1.00 35.08 ? 635 PHE A CA 1 ATOM 5023 C C . PHE A 1 329 ? 9.862 242.961 -15.637 1.00 29.99 ? 635 PHE A C 1 ATOM 5024 O O . PHE A 1 329 ? 9.180 242.855 -16.659 1.00 30.79 ? 635 PHE A O 1 ATOM 5025 C CB . PHE A 1 329 ? 10.464 240.635 -14.978 1.00 31.12 ? 635 PHE A CB 1 ATOM 5026 C CG . PHE A 1 329 ? 10.636 239.623 -13.896 1.00 32.19 ? 635 PHE A CG 1 ATOM 5027 C CD1 . PHE A 1 329 ? 9.552 238.932 -13.386 1.00 37.95 ? 635 PHE A CD1 1 ATOM 5028 C CD2 . PHE A 1 329 ? 11.898 239.328 -13.412 1.00 34.42 ? 635 PHE A CD2 1 ATOM 5029 C CE1 . PHE A 1 329 ? 9.730 237.968 -12.393 1.00 34.61 ? 635 PHE A CE1 1 ATOM 5030 C CE2 . PHE A 1 329 ? 12.077 238.380 -12.429 1.00 30.95 ? 635 PHE A CE2 1 ATOM 5031 C CZ . PHE A 1 329 ? 10.991 237.696 -11.924 1.00 29.89 ? 635 PHE A CZ 1 ATOM 5032 H H . PHE A 1 329 ? 8.025 240.994 -14.686 1.00 37.54 ? 635 PHE A H 1 ATOM 5033 H HA . PHE A 1 329 ? 10.201 242.253 -13.742 1.00 42.10 ? 635 PHE A HA 1 ATOM 5034 H HB2 . PHE A 1 329 ? 9.945 240.224 -15.688 1.00 37.35 ? 635 PHE A HB2 1 ATOM 5035 H HB3 . PHE A 1 329 ? 11.346 240.867 -15.309 1.00 37.35 ? 635 PHE A HB3 1 ATOM 5036 H HD1 . PHE A 1 329 ? 8.698 239.111 -13.707 1.00 45.54 ? 635 PHE A HD1 1 ATOM 5037 H HD2 . PHE A 1 329 ? 12.636 239.781 -13.752 1.00 41.31 ? 635 PHE A HD2 1 ATOM 5038 H HE1 . PHE A 1 329 ? 8.996 237.511 -12.050 1.00 41.53 ? 635 PHE A HE1 1 ATOM 5039 H HE2 . PHE A 1 329 ? 12.931 238.196 -12.110 1.00 37.14 ? 635 PHE A HE2 1 ATOM 5040 H HZ . PHE A 1 329 ? 11.111 237.060 -11.257 1.00 35.87 ? 635 PHE A HZ 1 ATOM 5041 N N . LYS A 1 330 ? 10.722 243.962 -15.430 1.00 26.72 ? 636 LYS A N 1 ATOM 5042 C CA . LYS A 1 330 ? 11.092 244.921 -16.468 1.00 29.28 ? 636 LYS A CA 1 ATOM 5043 C C . LYS A 1 330 ? 12.609 245.002 -16.542 1.00 26.35 ? 636 LYS A C 1 ATOM 5044 O O . LYS A 1 330 ? 13.269 245.337 -15.553 1.00 25.64 ? 636 LYS A O 1 ATOM 5045 C CB . LYS A 1 330 ? 10.488 246.302 -16.198 1.00 34.79 ? 636 LYS A CB 1 ATOM 5046 C CG . LYS A 1 330 ? 8.990 246.397 -16.529 1.00 48.76 ? 636 LYS A CG 1 ATOM 5047 C CD . LYS A 1 330 ? 8.382 247.728 -16.091 1.00 60.85 ? 636 LYS A CD 1 ATOM 5048 C CE . LYS A 1 330 ? 6.859 247.727 -16.245 1.00 76.75 ? 636 LYS A CE 1 ATOM 5049 N NZ . LYS A 1 330 ? 6.212 248.934 -15.634 1.00 81.68 ? 636 LYS A NZ 1 ATOM 5050 H H . LYS A 1 330 ? 11.111 244.107 -14.677 1.00 32.07 ? 636 LYS A H 1 ATOM 5051 H HA . LYS A 1 330 ? 10.762 244.607 -17.325 1.00 35.13 ? 636 LYS A HA 1 ATOM 5052 H HB2 . LYS A 1 330 ? 10.598 246.513 -15.258 1.00 41.75 ? 636 LYS A HB2 1 ATOM 5053 H HB3 . LYS A 1 330 ? 10.953 246.958 -16.740 1.00 41.75 ? 636 LYS A HB3 1 ATOM 5054 H HG2 . LYS A 1 330 ? 8.871 246.313 -17.488 1.00 58.51 ? 636 LYS A HG2 1 ATOM 5055 H HG3 . LYS A 1 330 ? 8.518 245.685 -16.071 1.00 58.51 ? 636 LYS A HG3 1 ATOM 5056 H HD2 . LYS A 1 330 ? 8.593 247.884 -15.157 1.00 73.02 ? 636 LYS A HD2 1 ATOM 5057 H HD3 . LYS A 1 330 ? 8.742 248.441 -16.641 1.00 73.02 ? 636 LYS A HD3 1 ATOM 5058 H HE2 . LYS A 1 330 ? 6.637 247.713 -17.189 1.00 92.10 ? 636 LYS A HE2 1 ATOM 5059 H HE3 . LYS A 1 330 ? 6.498 246.940 -15.807 1.00 92.10 ? 636 LYS A HE3 1 ATOM 5060 H HZ1 . LYS A 1 330 ? 5.330 248.894 -15.745 1.00 98.01 ? 636 LYS A HZ1 1 ATOM 5061 H HZ2 . LYS A 1 330 ? 6.393 248.968 -14.763 1.00 98.01 ? 636 LYS A HZ2 1 ATOM 5062 H HZ3 . LYS A 1 330 ? 6.519 249.673 -16.022 1.00 98.01 ? 636 LYS A HZ3 1 ATOM 5063 N N . GLU A 1 331 ? 13.161 244.701 -17.712 1.00 27.08 ? 637 GLU A N 1 ATOM 5064 C CA . GLU A 1 331 ? 14.601 244.783 -17.884 1.00 30.23 ? 637 GLU A CA 1 ATOM 5065 C C . GLU A 1 331 ? 15.065 246.229 -17.768 1.00 32.05 ? 637 GLU A C 1 ATOM 5066 O O . GLU A 1 331 ? 14.344 247.162 -18.123 1.00 27.54 ? 637 GLU A O 1 ATOM 5067 C CB . GLU A 1 331 ? 15.014 244.215 -19.228 1.00 26.68 ? 637 GLU A CB 1 ATOM 5068 C CG . GLU A 1 331 ? 16.507 244.251 -19.434 1.00 33.27 ? 637 GLU A CG 1 ATOM 5069 C CD . GLU A 1 331 ? 16.919 243.523 -20.691 1.00 43.27 ? 637 GLU A CD 1 ATOM 5070 O OE1 . GLU A 1 331 ? 16.020 243.204 -21.500 1.00 48.31 ? 637 GLU A OE1 1 ATOM 5071 O OE2 . GLU A 1 331 ? 18.133 243.266 -20.864 1.00 44.02 ? 637 GLU A OE2 1 ATOM 5072 H H . GLU A 1 331 ? 12.729 244.451 -18.412 1.00 32.50 ? 637 GLU A H 1 ATOM 5073 H HA . GLU A 1 331 ? 15.037 244.267 -17.189 1.00 36.28 ? 637 GLU A HA 1 ATOM 5074 H HB2 . GLU A 1 331 ? 14.725 243.291 -19.284 1.00 32.02 ? 637 GLU A HB2 1 ATOM 5075 H HB3 . GLU A 1 331 ? 14.600 244.737 -19.934 1.00 32.02 ? 637 GLU A HB3 1 ATOM 5076 H HG2 . GLU A 1 331 ? 16.796 245.174 -19.510 1.00 39.93 ? 637 GLU A HG2 1 ATOM 5077 H HG3 . GLU A 1 331 ? 16.943 243.825 -18.680 1.00 39.93 ? 637 GLU A HG3 1 ATOM 5078 N N . VAL A 1 332 ? 16.261 246.408 -17.218 1.00 29.51 ? 638 VAL A N 1 ATOM 5079 C CA . VAL A 1 332 ? 16.834 247.724 -16.991 1.00 24.14 ? 638 VAL A CA 1 ATOM 5080 C C . VAL A 1 332 ? 18.315 247.634 -17.323 1.00 25.93 ? 638 VAL A C 1 ATOM 5081 O O . VAL A 1 332 ? 18.952 246.590 -17.140 1.00 23.06 ? 638 VAL A O 1 ATOM 5082 C CB . VAL A 1 332 ? 16.619 248.227 -15.537 1.00 27.37 ? 638 VAL A CB 1 ATOM 5083 C CG1 . VAL A 1 332 ? 15.153 248.358 -15.221 1.00 28.17 ? 638 VAL A CG1 1 ATOM 5084 C CG2 . VAL A 1 332 ? 17.281 247.317 -14.531 1.00 22.08 ? 638 VAL A CG2 1 ATOM 5085 H H . VAL A 1 332 ? 16.770 245.764 -16.963 1.00 35.41 ? 638 VAL A H 1 ATOM 5086 H HA . VAL A 1 332 ? 16.424 248.361 -17.596 1.00 28.97 ? 638 VAL A HA 1 ATOM 5087 H HB . VAL A 1 332 ? 17.020 249.106 -15.449 1.00 32.84 ? 638 VAL A HB 1 ATOM 5088 H HG11 . VAL A 1 332 ? 15.054 248.673 -14.309 1.00 33.81 ? 638 VAL A HG11 1 ATOM 5089 H HG12 . VAL A 1 332 ? 14.753 248.992 -15.836 1.00 33.81 ? 638 VAL A HG12 1 ATOM 5090 H HG13 . VAL A 1 332 ? 14.731 247.490 -15.320 1.00 33.81 ? 638 VAL A HG13 1 ATOM 5091 H HG21 . VAL A 1 332 ? 17.124 247.665 -13.639 1.00 26.50 ? 638 VAL A HG21 1 ATOM 5092 H HG22 . VAL A 1 332 ? 16.901 246.428 -14.612 1.00 26.50 ? 638 VAL A HG22 1 ATOM 5093 H HG23 . VAL A 1 332 ? 18.234 247.287 -14.712 1.00 26.50 ? 638 VAL A HG23 1 ATOM 5094 N N . SER A 1 333 ? 18.854 248.728 -17.852 1.00 24.63 ? 639 SER A N 1 ATOM 5095 C CA . SER A 1 333 ? 20.294 248.834 -18.028 1.00 25.23 ? 639 SER A CA 1 ATOM 5096 C C . SER A 1 333 ? 20.998 248.718 -16.671 1.00 23.63 ? 639 SER A C 1 ATOM 5097 O O . SER A 1 333 ? 20.440 249.044 -15.619 1.00 19.33 ? 639 SER A O 1 ATOM 5098 C CB . SER A 1 333 ? 20.633 250.162 -18.720 1.00 27.09 ? 639 SER A CB 1 ATOM 5099 O OG . SER A 1 333 ? 22.016 250.283 -19.034 1.00 22.42 ? 639 SER A OG 1 ATOM 5100 H H . SER A 1 333 ? 18.410 249.416 -18.114 1.00 29.56 ? 639 SER A H 1 ATOM 5101 H HA . SER A 1 333 ? 20.602 248.108 -18.594 1.00 30.28 ? 639 SER A HA 1 ATOM 5102 H HB2 . SER A 1 333 ? 20.123 250.221 -19.543 1.00 32.51 ? 639 SER A HB2 1 ATOM 5103 H HB3 . SER A 1 333 ? 20.385 250.890 -18.130 1.00 32.51 ? 639 SER A HB3 1 ATOM 5104 H HG . SER A 1 333 ? 22.474 250.240 -18.331 1.00 26.91 ? 639 SER A HG 1 ATOM 5105 N N . ALA A 1 334 ? 22.239 248.229 -16.709 1.00 20.84 ? 640 ALA A N 1 ATOM 5106 C CA . ALA A 1 334 ? 22.973 247.921 -15.491 1.00 22.64 ? 640 ALA A CA 1 ATOM 5107 C C . ALA A 1 334 ? 23.043 249.095 -14.515 1.00 23.51 ? 640 ALA A C 1 ATOM 5108 O O . ALA A 1 334 ? 23.049 248.883 -13.298 1.00 23.27 ? 640 ALA A O 1 ATOM 5109 C CB . ALA A 1 334 ? 24.381 247.452 -15.859 1.00 22.26 ? 640 ALA A CB 1 ATOM 5110 H H . ALA A 1 334 ? 22.675 248.067 -17.432 1.00 25.01 ? 640 ALA A H 1 ATOM 5111 H HA . ALA A 1 334 ? 22.527 247.188 -15.038 1.00 27.17 ? 640 ALA A HA 1 ATOM 5112 H HB1 . ALA A 1 334 ? 24.868 247.248 -15.045 1.00 26.71 ? 640 ALA A HB1 1 ATOM 5113 H HB2 . ALA A 1 334 ? 24.315 246.659 -16.413 1.00 26.71 ? 640 ALA A HB2 1 ATOM 5114 H HB3 . ALA A 1 334 ? 24.832 248.160 -16.345 1.00 26.71 ? 640 ALA A HB3 1 ATOM 5115 N N . VAL A 1 335 ? 23.083 250.334 -15.015 1.00 21.15 ? 641 VAL A N 1 ATOM 5116 C CA . VAL A 1 335 ? 23.316 251.473 -14.128 1.00 21.27 ? 641 VAL A CA 1 ATOM 5117 C C . VAL A 1 335 ? 22.214 251.601 -13.087 1.00 20.85 ? 641 VAL A C 1 ATOM 5118 O O . VAL A 1 335 ? 22.430 252.177 -12.011 1.00 23.33 ? 641 VAL A O 1 ATOM 5119 C CB . VAL A 1 335 ? 23.465 252.775 -14.951 1.00 19.80 ? 641 VAL A CB 1 ATOM 5120 C CG1 . VAL A 1 335 ? 22.162 253.159 -15.628 1.00 18.34 ? 641 VAL A CG1 1 ATOM 5121 C CG2 . VAL A 1 335 ? 23.921 253.890 -14.080 1.00 19.65 ? 641 VAL A CG2 1 ATOM 5122 H H . VAL A 1 335 ? 22.980 250.537 -15.845 1.00 25.39 ? 641 VAL A H 1 ATOM 5123 H HA . VAL A 1 335 ? 24.151 251.329 -13.654 1.00 25.53 ? 641 VAL A HA 1 ATOM 5124 H HB . VAL A 1 335 ? 24.134 252.640 -15.640 1.00 23.76 ? 641 VAL A HB 1 ATOM 5125 H HG11 . VAL A 1 335 ? 22.297 253.977 -16.131 1.00 22.01 ? 641 VAL A HG11 1 ATOM 5126 H HG12 . VAL A 1 335 ? 21.894 252.443 -16.225 1.00 22.01 ? 641 VAL A HG12 1 ATOM 5127 H HG13 . VAL A 1 335 ? 21.483 253.296 -14.949 1.00 22.01 ? 641 VAL A HG13 1 ATOM 5128 H HG21 . VAL A 1 335 ? 24.007 254.694 -14.616 1.00 23.58 ? 641 VAL A HG21 1 ATOM 5129 H HG22 . VAL A 1 335 ? 23.267 254.028 -13.377 1.00 23.58 ? 641 VAL A HG22 1 ATOM 5130 H HG23 . VAL A 1 335 ? 24.779 253.656 -13.692 1.00 23.58 ? 641 VAL A HG23 1 ATOM 5131 N N . TYR A 1 336 ? 21.014 251.114 -13.394 1.00 22.88 ? 642 TYR A N 1 ATOM 5132 C CA . TYR A 1 336 ? 19.876 251.250 -12.494 1.00 28.25 ? 642 TYR A CA 1 ATOM 5133 C C . TYR A 1 336 ? 19.748 250.088 -11.521 1.00 28.59 ? 642 TYR A C 1 ATOM 5134 O O . TYR A 1 336 ? 18.805 250.074 -10.725 1.00 32.29 ? 642 TYR A O 1 ATOM 5135 C CB . TYR A 1 336 ? 18.570 251.378 -13.282 1.00 25.18 ? 642 TYR A CB 1 ATOM 5136 C CG . TYR A 1 336 ? 18.619 252.463 -14.294 1.00 24.25 ? 642 TYR A CG 1 ATOM 5137 C CD1 . TYR A 1 336 ? 18.730 253.793 -13.901 1.00 28.74 ? 642 TYR A CD1 1 ATOM 5138 C CD2 . TYR A 1 336 ? 18.584 252.169 -15.653 1.00 21.05 ? 642 TYR A CD2 1 ATOM 5139 C CE1 . TYR A 1 336 ? 18.797 254.819 -14.834 1.00 23.28 ? 642 TYR A CE1 1 ATOM 5140 C CE2 . TYR A 1 336 ? 18.647 253.177 -16.596 1.00 20.42 ? 642 TYR A CE2 1 ATOM 5141 C CZ . TYR A 1 336 ? 18.755 254.494 -16.183 1.00 21.91 ? 642 TYR A CZ 1 ATOM 5142 O OH . TYR A 1 336 ? 18.819 255.474 -17.113 1.00 20.79 ? 642 TYR A OH 1 ATOM 5143 H H . TYR A 1 336 ? 20.834 250.696 -14.125 1.00 27.45 ? 642 TYR A H 1 ATOM 5144 H HA . TYR A 1 336 ? 19.987 252.061 -11.973 1.00 33.90 ? 642 TYR A HA 1 ATOM 5145 H HB2 . TYR A 1 336 ? 18.397 250.543 -13.745 1.00 30.22 ? 642 TYR A HB2 1 ATOM 5146 H HB3 . TYR A 1 336 ? 17.846 251.573 -12.667 1.00 30.22 ? 642 TYR A HB3 1 ATOM 5147 H HD1 . TYR A 1 336 ? 18.760 253.999 -12.994 1.00 34.49 ? 642 TYR A HD1 1 ATOM 5148 H HD2 . TYR A 1 336 ? 18.516 251.284 -15.930 1.00 25.27 ? 642 TYR A HD2 1 ATOM 5149 H HE1 . TYR A 1 336 ? 18.868 255.705 -14.562 1.00 27.93 ? 642 TYR A HE1 1 ATOM 5150 H HE2 . TYR A 1 336 ? 18.621 252.972 -17.503 1.00 24.51 ? 642 TYR A HE2 1 ATOM 5151 H HH . TYR A 1 336 ? 18.784 255.142 -17.884 1.00 24.95 ? 642 TYR A HH 1 ATOM 5152 N N . TYR A 1 337 ? 20.654 249.116 -11.582 1.00 26.29 ? 643 TYR A N 1 ATOM 5153 C CA . TYR A 1 337 ? 20.641 247.974 -10.672 1.00 34.37 ? 643 TYR A CA 1 ATOM 5154 C C . TYR A 1 337 ? 21.545 248.293 -9.477 1.00 36.56 ? 643 TYR A C 1 ATOM 5155 O O . TYR A 1 337 ? 22.755 248.055 -9.497 1.00 32.86 ? 643 TYR A O 1 ATOM 5156 C CB . TYR A 1 337 ? 21.077 246.717 -11.413 1.00 33.95 ? 643 TYR A CB 1 ATOM 5157 C CG . TYR A 1 337 ? 20.883 245.447 -10.611 1.00 40.47 ? 643 TYR A CG 1 ATOM 5158 C CD1 . TYR A 1 337 ? 19.622 244.871 -10.464 1.00 35.97 ? 643 TYR A CD1 1 ATOM 5159 C CD2 . TYR A 1 337 ? 21.961 244.826 -9.996 1.00 47.48 ? 643 TYR A CD2 1 ATOM 5160 C CE1 . TYR A 1 337 ? 19.445 243.715 -9.716 1.00 37.09 ? 643 TYR A CE1 1 ATOM 5161 C CE2 . TYR A 1 337 ? 21.794 243.672 -9.251 1.00 50.94 ? 643 TYR A CE2 1 ATOM 5162 C CZ . TYR A 1 337 ? 20.538 243.121 -9.116 1.00 42.36 ? 643 TYR A CZ 1 ATOM 5163 O OH . TYR A 1 337 ? 20.394 241.973 -8.375 1.00 41.81 ? 643 TYR A OH 1 ATOM 5164 H H . TYR A 1 337 ? 21.298 249.095 -12.152 1.00 31.55 ? 643 TYR A H 1 ATOM 5165 H HA . TYR A 1 337 ? 19.739 247.836 -10.344 1.00 41.24 ? 643 TYR A HA 1 ATOM 5166 H HB2 . TYR A 1 337 ? 20.557 246.636 -12.228 1.00 40.74 ? 643 TYR A HB2 1 ATOM 5167 H HB3 . TYR A 1 337 ? 22.020 246.791 -11.629 1.00 40.74 ? 643 TYR A HB3 1 ATOM 5168 H HD1 . TYR A 1 337 ? 18.886 245.274 -10.865 1.00 43.17 ? 643 TYR A HD1 1 ATOM 5169 H HD2 . TYR A 1 337 ? 22.810 245.196 -10.081 1.00 56.98 ? 643 TYR A HD2 1 ATOM 5170 H HE1 . TYR A 1 337 ? 18.599 243.340 -9.625 1.00 44.51 ? 643 TYR A HE1 1 ATOM 5171 H HE2 . TYR A 1 337 ? 22.527 243.268 -8.845 1.00 61.12 ? 643 TYR A HE2 1 ATOM 5172 H HH . TYR A 1 337 ? 21.139 241.730 -8.074 1.00 50.17 ? 643 TYR A HH 1 ATOM 5173 N N . ASN A 1 338 ? 20.940 248.821 -8.408 1.00 32.54 ? 644 ASN A N 1 ATOM 5174 C CA . ASN A 1 338 ? 21.680 249.354 -7.257 1.00 47.84 ? 644 ASN A CA 1 ATOM 5175 C C . ASN A 1 338 ? 22.106 248.278 -6.245 1.00 53.99 ? 644 ASN A C 1 ATOM 5176 O O . ASN A 1 338 ? 21.795 248.362 -5.058 1.00 37.34 ? 644 ASN A O 1 ATOM 5177 C CB . ASN A 1 338 ? 20.834 250.412 -6.561 1.00 46.89 ? 644 ASN A CB 1 ATOM 5178 C CG . ASN A 1 338 ? 21.565 251.085 -5.390 1.00 54.97 ? 644 ASN A CG 1 ATOM 5179 O OD1 . ASN A 1 338 ? 22.788 250.996 -5.264 1.00 48.17 ? 644 ASN A OD1 1 ATOM 5180 N ND2 . ASN A 1 338 ? 20.807 251.766 -4.535 1.00 47.99 ? 644 ASN A ND2 1 ATOM 5181 H H . ASN A 1 338 ? 20.086 248.884 -8.324 1.00 39.05 ? 644 ASN A H 1 ATOM 5182 H HA . ASN A 1 338 ? 22.486 249.787 -7.581 1.00 57.41 ? 644 ASN A HA 1 ATOM 5183 H HB2 . ASN A 1 338 ? 20.599 251.101 -7.202 1.00 56.27 ? 644 ASN A HB2 1 ATOM 5184 H HB3 . ASN A 1 338 ? 20.030 249.995 -6.213 1.00 56.27 ? 644 ASN A HB3 1 ATOM 5185 H HD21 . ASN A 1 338 ? 21.167 252.161 -3.862 1.00 57.59 ? 644 ASN A HD21 1 ATOM 5186 H HD22 . ASN A 1 338 ? 19.957 251.811 -4.656 1.00 57.59 ? 644 ASN A HD22 1 ATOM 5187 N N . SER A 1 339 ? 22.855 247.274 -6.713 1.00 57.44 ? 645 SER A N 1 ATOM 5188 C CA . SER A 1 339 ? 23.591 246.386 -5.806 1.00 61.37 ? 645 SER A CA 1 ATOM 5189 C C . SER A 1 339 ? 24.519 245.500 -6.633 1.00 60.28 ? 645 SER A C 1 ATOM 5190 O O . SER A 1 339 ? 24.523 245.551 -7.867 1.00 55.87 ? 645 SER A O 1 ATOM 5191 C CB . SER A 1 339 ? 22.664 245.539 -4.919 1.00 56.75 ? 645 SER A CB 1 ATOM 5192 O OG . SER A 1 339 ? 22.123 244.438 -5.615 1.00 61.62 ? 645 SER A OG 1 ATOM 5193 H H . SER A 1 339 ? 22.954 247.087 -7.546 1.00 68.93 ? 645 SER A H 1 ATOM 5194 H HA . SER A 1 339 ? 24.144 246.927 -5.221 1.00 73.65 ? 645 SER A HA 1 ATOM 5195 H HB2 . SER A 1 339 ? 23.173 245.209 -4.162 1.00 68.10 ? 645 SER A HB2 1 ATOM 5196 H HB3 . SER A 1 339 ? 21.936 246.098 -4.606 1.00 68.10 ? 645 SER A HB3 1 ATOM 5197 H HG . SER A 1 339 ? 21.622 243.995 -5.107 1.00 73.94 ? 645 SER A HG 1 ATOM 5198 N N . TRP A 1 340 ? 25.326 244.698 -5.928 1.00 70.19 ? 646 TRP A N 1 ATOM 5199 C CA . TRP A 1 340 ? 26.278 243.776 -6.536 1.00 75.46 ? 646 TRP A CA 1 ATOM 5200 C C . TRP A 1 340 ? 25.817 242.328 -6.483 1.00 70.29 ? 646 TRP A C 1 ATOM 5201 O O . TRP A 1 340 ? 26.468 241.466 -7.085 1.00 70.28 ? 646 TRP A O 1 ATOM 5202 C CB . TRP A 1 340 ? 27.645 243.877 -5.840 1.00 87.30 ? 646 TRP A CB 1 ATOM 5203 C CG . TRP A 1 340 ? 28.391 245.153 -6.121 1.00 104.37 ? 646 TRP A CG 1 ATOM 5204 C CD1 . TRP A 1 340 ? 28.338 246.309 -5.396 1.00 102.66 ? 646 TRP A CD1 1 ATOM 5205 C CD2 . TRP A 1 340 ? 29.305 245.399 -7.201 1.00 107.93 ? 646 TRP A CD2 1 ATOM 5206 N NE1 . TRP A 1 340 ? 29.157 247.259 -5.958 1.00 105.97 ? 646 TRP A NE1 1 ATOM 5207 C CE2 . TRP A 1 340 ? 29.763 246.726 -7.065 1.00 109.19 ? 646 TRP A CE2 1 ATOM 5208 C CE3 . TRP A 1 340 ? 29.780 244.626 -8.268 1.00 101.62 ? 646 TRP A CE3 1 ATOM 5209 C CZ2 . TRP A 1 340 ? 30.671 247.299 -7.957 1.00 106.71 ? 646 TRP A CZ2 1 ATOM 5210 C CZ3 . TRP A 1 340 ? 30.683 245.197 -9.152 1.00 103.51 ? 646 TRP A CZ3 1 ATOM 5211 C CH2 . TRP A 1 340 ? 31.117 246.522 -8.991 1.00 101.09 ? 646 TRP A CH2 1 ATOM 5212 H H . TRP A 1 340 ? 25.335 244.675 -5.069 1.00 84.22 ? 646 TRP A H 1 ATOM 5213 H HA . TRP A 1 340 ? 26.398 244.017 -7.468 1.00 90.55 ? 646 TRP A HA 1 ATOM 5214 H HB2 . TRP A 1 340 ? 27.511 243.819 -4.881 1.00 104.76 ? 646 TRP A HB2 1 ATOM 5215 H HB3 . TRP A 1 340 ? 28.200 243.139 -6.138 1.00 104.76 ? 646 TRP A HB3 1 ATOM 5216 H HD1 . TRP A 1 340 ? 27.820 246.436 -4.634 1.00 123.19 ? 646 TRP A HD1 1 ATOM 5217 H HE1 . TRP A 1 340 ? 29.271 248.058 -5.661 1.00 127.16 ? 646 TRP A HE1 1 ATOM 5218 H HE3 . TRP A 1 340 ? 29.495 243.748 -8.382 1.00 121.94 ? 646 TRP A HE3 1 ATOM 5219 H HZ2 . TRP A 1 340 ? 30.962 248.176 -7.852 1.00 128.05 ? 646 TRP A HZ2 1 ATOM 5220 H HZ3 . TRP A 1 340 ? 31.004 244.694 -9.865 1.00 124.22 ? 646 TRP A HZ3 1 ATOM 5221 H HH2 . TRP A 1 340 ? 31.724 246.878 -9.599 1.00 121.30 ? 646 TRP A HH2 1 ATOM 5222 N N . GLN A 1 341 ? 24.730 242.042 -5.775 1.00 54.41 ? 647 GLN A N 1 ATOM 5223 C CA . GLN A 1 341 ? 24.231 240.683 -5.635 1.00 57.70 ? 647 GLN A CA 1 ATOM 5224 C C . GLN A 1 341 ? 23.291 240.329 -6.785 1.00 49.01 ? 647 GLN A C 1 ATOM 5225 O O . GLN A 1 341 ? 22.945 241.162 -7.625 1.00 50.54 ? 647 GLN A O 1 ATOM 5226 C CB . GLN A 1 341 ? 23.524 240.522 -4.289 1.00 50.50 ? 647 GLN A CB 1 ATOM 5227 C CG . GLN A 1 341 ? 24.467 240.653 -3.094 1.00 60.07 ? 647 GLN A CG 1 ATOM 5228 C CD . GLN A 1 341 ? 23.741 240.787 -1.767 1.00 64.05 ? 647 GLN A CD 1 ATOM 5229 O OE1 . GLN A 1 341 ? 22.579 241.191 -1.712 1.00 61.95 ? 647 GLN A OE1 1 ATOM 5230 N NE2 . GLN A 1 341 ? 24.427 240.446 -0.688 1.00 69.14 ? 647 GLN A NE2 1 ATOM 5231 H H . GLN A 1 341 ? 24.258 242.629 -5.361 1.00 65.29 ? 647 GLN A H 1 ATOM 5232 H HA . GLN A 1 341 ? 24.980 240.067 -5.657 1.00 69.24 ? 647 GLN A HA 1 ATOM 5233 H HB2 . GLN A 1 341 ? 22.842 241.207 -4.208 1.00 60.60 ? 647 GLN A HB2 1 ATOM 5234 H HB3 . GLN A 1 341 ? 23.116 239.642 -4.252 1.00 60.60 ? 647 GLN A HB3 1 ATOM 5235 H HG2 . GLN A 1 341 ? 25.028 239.863 -3.049 1.00 72.08 ? 647 GLN A HG2 1 ATOM 5236 H HG3 . GLN A 1 341 ? 25.018 241.442 -3.214 1.00 72.08 ? 647 GLN A HG3 1 ATOM 5237 H HE21 . GLN A 1 341 ? 25.237 240.167 -0.765 1.00 82.97 ? 647 GLN A HE21 1 ATOM 5238 H HE22 . GLN A 1 341 ? 24.064 240.503 0.089 1.00 82.97 ? 647 GLN A HE22 1 ATOM 5239 N N . ASN A 1 342 ? 22.881 239.063 -6.817 1.00 41.70 ? 648 ASN A N 1 ATOM 5240 C CA . ASN A 1 342 ? 21.963 238.577 -7.840 1.00 42.49 ? 648 ASN A CA 1 ATOM 5241 C C . ASN A 1 342 ? 20.507 238.858 -7.500 1.00 38.03 ? 648 ASN A C 1 ATOM 5242 O O . ASN A 1 342 ? 19.636 238.631 -8.349 1.00 32.01 ? 648 ASN A O 1 ATOM 5243 C CB . ASN A 1 342 ? 22.148 237.068 -8.058 1.00 42.03 ? 648 ASN A CB 1 ATOM 5244 C CG . ASN A 1 342 ? 23.127 236.740 -9.181 1.00 56.60 ? 648 ASN A CG 1 ATOM 5245 O OD1 . ASN A 1 342 ? 23.541 237.612 -9.956 1.00 56.89 ? 648 ASN A OD1 1 ATOM 5246 N ND2 . ASN A 1 342 ? 23.473 235.458 -9.294 1.00 58.66 ? 648 ASN A ND2 1 ATOM 5247 H H . ASN A 1 342 ? 23.123 238.462 -6.251 1.00 50.04 ? 648 ASN A H 1 ATOM 5248 H HA . ASN A 1 342 ? 22.163 239.024 -8.677 1.00 50.99 ? 648 ASN A HA 1 ATOM 5249 H HB2 . ASN A 1 342 ? 22.488 236.672 -7.240 1.00 50.44 ? 648 ASN A HB2 1 ATOM 5250 H HB3 . ASN A 1 342 ? 21.291 236.675 -8.284 1.00 50.44 ? 648 ASN A HB3 1 ATOM 5251 H HD21 . ASN A 1 342 ? 24.022 235.214 -9.909 1.00 70.39 ? 648 ASN A HD21 1 ATOM 5252 H HD22 . ASN A 1 342 ? 23.148 234.876 -8.751 1.00 70.39 ? 648 ASN A HD22 1 ATOM 5253 N N . LEU A 1 343 ? 20.229 239.324 -6.281 1.00 31.96 ? 649 LEU A N 1 ATOM 5254 C CA . LEU A 1 343 ? 18.906 239.776 -5.874 1.00 40.33 ? 649 LEU A CA 1 ATOM 5255 C C . LEU A 1 343 ? 19.010 241.137 -5.196 1.00 41.27 ? 649 LEU A C 1 ATOM 5256 O O . LEU A 1 343 ? 20.017 241.460 -4.558 1.00 37.76 ? 649 LEU A O 1 ATOM 5257 C CB . LEU A 1 343 ? 18.223 238.794 -4.909 1.00 34.32 ? 649 LEU A CB 1 ATOM 5258 C CG . LEU A 1 343 ? 17.693 237.485 -5.475 1.00 28.97 ? 649 LEU A CG 1 ATOM 5259 C CD1 . LEU A 1 343 ? 17.173 236.623 -4.339 1.00 33.31 ? 649 LEU A CD1 1 ATOM 5260 C CD2 . LEU A 1 343 ? 16.603 237.732 -6.495 1.00 33.81 ? 649 LEU A CD2 1 ATOM 5261 H H . LEU A 1 343 ? 20.814 239.388 -5.654 1.00 38.36 ? 649 LEU A H 1 ATOM 5262 H HA . LEU A 1 343 ? 18.344 239.869 -6.660 1.00 48.40 ? 649 LEU A HA 1 ATOM 5263 H HB2 . LEU A 1 343 ? 18.863 238.564 -4.218 1.00 41.18 ? 649 LEU A HB2 1 ATOM 5264 H HB3 . LEU A 1 343 ? 17.470 239.251 -4.504 1.00 41.18 ? 649 LEU A HB3 1 ATOM 5265 H HG . LEU A 1 343 ? 18.416 237.009 -5.912 1.00 34.76 ? 649 LEU A HG 1 ATOM 5266 H HD11 . LEU A 1 343 ? 16.836 235.790 -4.704 1.00 39.97 ? 649 LEU A HD11 1 ATOM 5267 H HD12 . LEU A 1 343 ? 17.899 236.444 -3.721 1.00 39.97 ? 649 LEU A HD12 1 ATOM 5268 H HD13 . LEU A 1 343 ? 16.460 237.098 -3.884 1.00 39.97 ? 649 LEU A HD13 1 ATOM 5269 H HD21 . LEU A 1 343 ? 16.289 236.879 -6.834 1.00 40.57 ? 649 LEU A HD21 1 ATOM 5270 H HD22 . LEU A 1 343 ? 15.874 238.208 -6.068 1.00 40.57 ? 649 LEU A HD22 1 ATOM 5271 H HD23 . LEU A 1 343 ? 16.966 238.264 -7.221 1.00 40.57 ? 649 LEU A HD23 1 ATOM 5272 N N . LEU A 1 344 ? 17.935 241.917 -5.318 1.00 35.55 ? 650 LEU A N 1 ATOM 5273 C CA . LEU A 1 344 ? 17.876 243.288 -4.839 1.00 30.30 ? 650 LEU A CA 1 ATOM 5274 C C . LEU A 1 344 ? 16.652 243.442 -3.949 1.00 34.10 ? 650 LEU A C 1 ATOM 5275 O O . LEU A 1 344 ? 15.551 243.032 -4.334 1.00 30.72 ? 650 LEU A O 1 ATOM 5276 C CB . LEU A 1 344 ? 17.814 244.256 -6.028 1.00 47.59 ? 650 LEU A CB 1 ATOM 5277 C CG . LEU A 1 344 ? 17.880 245.761 -5.792 1.00 46.88 ? 650 LEU A CG 1 ATOM 5278 C CD1 . LEU A 1 344 ? 19.149 246.116 -5.034 1.00 59.33 ? 650 LEU A CD1 1 ATOM 5279 C CD2 . LEU A 1 344 ? 17.828 246.489 -7.138 1.00 43.73 ? 650 LEU A CD2 1 ATOM 5280 H H . LEU A 1 344 ? 17.205 241.658 -5.691 1.00 42.66 ? 650 LEU A H 1 ATOM 5281 H HA . LEU A 1 344 ? 18.668 243.487 -4.316 1.00 36.36 ? 650 LEU A HA 1 ATOM 5282 H HB2 . LEU A 1 344 ? 18.553 244.038 -6.618 1.00 57.11 ? 650 LEU A HB2 1 ATOM 5283 H HB3 . LEU A 1 344 ? 16.982 244.087 -6.497 1.00 57.11 ? 650 LEU A HB3 1 ATOM 5284 H HG . LEU A 1 344 ? 17.117 246.039 -5.262 1.00 56.25 ? 650 LEU A HG 1 ATOM 5285 H HD11 . LEU A 1 344 ? 19.174 247.075 -4.893 1.00 71.19 ? 650 LEU A HD11 1 ATOM 5286 H HD12 . LEU A 1 344 ? 19.146 245.655 -4.181 1.00 71.19 ? 650 LEU A HD12 1 ATOM 5287 H HD13 . LEU A 1 344 ? 19.917 245.838 -5.558 1.00 71.19 ? 650 LEU A HD13 1 ATOM 5288 H HD21 . LEU A 1 344 ? 17.870 247.446 -6.981 1.00 52.47 ? 650 LEU A HD21 1 ATOM 5289 H HD22 . LEU A 1 344 ? 18.584 246.209 -7.678 1.00 52.47 ? 650 LEU A HD22 1 ATOM 5290 H HD23 . LEU A 1 344 ? 16.998 246.264 -7.587 1.00 52.47 ? 650 LEU A HD23 1 ATOM 5291 N N . TYR A 1 345 ? 16.846 244.032 -2.766 1.00 40.23 ? 651 TYR A N 1 ATOM 5292 C CA . TYR A 1 345 ? 15.818 244.090 -1.736 1.00 38.57 ? 651 TYR A CA 1 ATOM 5293 C C . TYR A 1 345 ? 15.492 245.536 -1.375 1.00 42.40 ? 651 TYR A C 1 ATOM 5294 O O . TYR A 1 345 ? 16.354 246.418 -1.423 1.00 36.32 ? 651 TYR A O 1 ATOM 5295 C CB . TYR A 1 345 ? 16.262 243.352 -0.469 1.00 37.61 ? 651 TYR A CB 1 ATOM 5296 C CG . TYR A 1 345 ? 16.501 241.863 -0.628 1.00 39.98 ? 651 TYR A CG 1 ATOM 5297 C CD1 . TYR A 1 345 ? 15.460 240.953 -0.476 1.00 44.66 ? 651 TYR A CD1 1 ATOM 5298 C CD2 . TYR A 1 345 ? 17.770 241.366 -0.897 1.00 35.32 ? 651 TYR A CD2 1 ATOM 5299 C CE1 . TYR A 1 345 ? 15.670 239.591 -0.606 1.00 47.15 ? 651 TYR A CE1 1 ATOM 5300 C CE2 . TYR A 1 345 ? 17.990 239.999 -1.027 1.00 44.33 ? 651 TYR A CE2 1 ATOM 5301 C CZ . TYR A 1 345 ? 16.935 239.121 -0.881 1.00 43.64 ? 651 TYR A CZ 1 ATOM 5302 O OH . TYR A 1 345 ? 17.145 237.770 -1.012 1.00 52.71 ? 651 TYR A OH 1 ATOM 5303 H H . TYR A 1 345 ? 17.582 244.412 -2.536 1.00 48.27 ? 651 TYR A H 1 ATOM 5304 H HA . TYR A 1 345 ? 15.009 243.669 -2.067 1.00 46.28 ? 651 TYR A HA 1 ATOM 5305 H HB2 . TYR A 1 345 ? 17.091 243.748 -0.159 1.00 45.13 ? 651 TYR A HB2 1 ATOM 5306 H HB3 . TYR A 1 345 ? 15.577 243.465 0.207 1.00 45.13 ? 651 TYR A HB3 1 ATOM 5307 H HD1 . TYR A 1 345 ? 14.604 241.266 -0.291 1.00 53.59 ? 651 TYR A HD1 1 ATOM 5308 H HD2 . TYR A 1 345 ? 18.482 241.956 -0.996 1.00 42.38 ? 651 TYR A HD2 1 ATOM 5309 H HE1 . TYR A 1 345 ? 14.961 238.997 -0.508 1.00 56.58 ? 651 TYR A HE1 1 ATOM 5310 H HE2 . TYR A 1 345 ? 18.842 239.678 -1.214 1.00 53.20 ? 651 TYR A HE2 1 ATOM 5311 H HH . TYR A 1 345 ? 17.955 237.620 -1.177 1.00 63.25 ? 651 TYR A HH 1 ATOM 5312 N N . ASP A 1 346 ? 14.240 245.767 -0.994 1.00 48.29 ? 652 ASP A N 1 ATOM 5313 C CA . ASP A 1 346 ? 13.803 247.075 -0.533 1.00 57.94 ? 652 ASP A CA 1 ATOM 5314 C C . ASP A 1 346 ? 14.076 247.209 0.968 1.00 63.13 ? 652 ASP A C 1 ATOM 5315 O O . ASP A 1 346 ? 14.811 246.418 1.569 1.00 56.45 ? 652 ASP A O 1 ATOM 5316 C CB . ASP A 1 346 ? 12.327 247.291 -0.880 1.00 58.92 ? 652 ASP A CB 1 ATOM 5317 C CG . ASP A 1 346 ? 11.381 246.381 -0.086 1.00 73.62 ? 652 ASP A CG 1 ATOM 5318 O OD1 . ASP A 1 346 ? 11.852 245.551 0.725 1.00 68.12 ? 652 ASP A OD1 1 ATOM 5319 O OD2 . ASP A 1 346 ? 10.149 246.490 -0.285 1.00 72.94 ? 652 ASP A OD2 1 ATOM 5320 H H . ASP A 1 346 ? 13.618 245.173 -0.994 1.00 57.95 ? 652 ASP A H 1 ATOM 5321 H HA . ASP A 1 346 ? 14.318 247.757 -0.991 1.00 69.53 ? 652 ASP A HA 1 ATOM 5322 H HB2 . ASP A 1 346 ? 12.089 248.211 -0.686 1.00 70.70 ? 652 ASP A HB2 1 ATOM 5323 H HB3 . ASP A 1 346 ? 12.195 247.107 -1.824 1.00 70.70 ? 652 ASP A HB3 1 ATOM 5324 N N . SER A 1 347 ? 13.485 248.227 1.593 1.00 68.01 ? 653 SER A N 1 ATOM 5325 C CA . SER A 1 347 ? 13.706 248.450 3.019 1.00 77.63 ? 653 SER A CA 1 ATOM 5326 C C . SER A 1 347 ? 12.938 247.442 3.866 1.00 76.20 ? 653 SER A C 1 ATOM 5327 O O . SER A 1 347 ? 13.427 247.003 4.912 1.00 70.30 ? 653 SER A O 1 ATOM 5328 C CB . SER A 1 347 ? 13.307 249.879 3.388 1.00 79.21 ? 653 SER A CB 1 ATOM 5329 O OG . SER A 1 347 ? 12.001 250.176 2.922 1.00 84.99 ? 653 SER A OG 1 ATOM 5330 H H . SER A 1 347 ? 12.959 248.796 1.219 1.00 81.61 ? 653 SER A H 1 ATOM 5331 H HA . SER A 1 347 ? 14.651 248.344 3.212 1.00 93.16 ? 653 SER A HA 1 ATOM 5332 H HB2 . SER A 1 347 ? 13.328 249.973 4.353 1.00 95.05 ? 653 SER A HB2 1 ATOM 5333 H HB3 . SER A 1 347 ? 13.935 250.497 2.981 1.00 95.05 ? 653 SER A HB3 1 ATOM 5334 H HG . SER A 1 347 ? 11.794 250.963 3.131 1.00 101.99 ? 653 SER A HG 1 ATOM 5335 N N . ASN A 1 348 ? 11.736 247.063 3.434 1.00 83.50 ? 654 ASN A N 1 ATOM 5336 C CA . ASN A 1 348 ? 10.913 246.116 4.173 1.00 76.83 ? 654 ASN A CA 1 ATOM 5337 C C . ASN A 1 348 ? 11.288 244.661 3.906 1.00 75.44 ? 654 ASN A C 1 ATOM 5338 O O . ASN A 1 348 ? 10.599 243.766 4.405 1.00 75.40 ? 654 ASN A O 1 ATOM 5339 C CB . ASN A 1 348 ? 9.434 246.340 3.836 1.00 80.71 ? 654 ASN A CB 1 ATOM 5340 H H . ASN A 1 348 ? 11.374 247.346 2.707 1.00 100.20 ? 654 ASN A H 1 ATOM 5341 H HA . ASN A 1 348 ? 11.028 246.280 5.122 1.00 92.19 ? 654 ASN A HA 1 ATOM 5342 H HB2 . ASN A 1 348 ? 9.188 247.245 4.083 1.00 96.85 ? 654 ASN A HB2 1 ATOM 5343 H HB3 . ASN A 1 348 ? 9.304 246.210 2.884 1.00 96.85 ? 654 ASN A HB3 1 ATOM 5344 N N . GLY A 1 349 ? 12.341 244.399 3.128 1.00 76.66 ? 655 GLY A N 1 ATOM 5345 C CA . GLY A 1 349 ? 12.807 243.046 2.881 1.00 71.86 ? 655 GLY A CA 1 ATOM 5346 C C . GLY A 1 349 ? 12.274 242.380 1.626 1.00 68.52 ? 655 GLY A C 1 ATOM 5347 O O . GLY A 1 349 ? 12.602 241.211 1.379 1.00 52.11 ? 655 GLY A O 1 ATOM 5348 H H . GLY A 1 349 ? 12.806 245.002 2.729 1.00 91.99 ? 655 GLY A H 1 ATOM 5349 H HA2 . GLY A 1 349 ? 13.775 243.057 2.821 1.00 86.23 ? 655 GLY A HA2 1 ATOM 5350 H HA3 . GLY A 1 349 ? 12.562 242.490 3.637 1.00 86.23 ? 655 GLY A HA3 1 ATOM 5351 N N . ASN A 1 350 ? 11.478 243.076 0.819 1.00 71.48 ? 656 ASN A N 1 ATOM 5352 C CA . ASN A 1 350 ? 10.868 242.478 -0.362 1.00 70.33 ? 656 ASN A CA 1 ATOM 5353 C C . ASN A 1 350 ? 11.791 242.589 -1.570 1.00 56.09 ? 656 ASN A C 1 ATOM 5354 O O . ASN A 1 350 ? 12.480 243.597 -1.753 1.00 43.45 ? 656 ASN A O 1 ATOM 5355 C CB . ASN A 1 350 ? 9.533 243.153 -0.674 1.00 69.05 ? 656 ASN A CB 1 ATOM 5356 C CG . ASN A 1 350 ? 8.601 243.169 0.515 1.00 86.65 ? 656 ASN A CG 1 ATOM 5357 O OD1 . ASN A 1 350 ? 8.628 242.264 1.353 1.00 90.41 ? 656 ASN A OD1 1 ATOM 5358 N ND2 . ASN A 1 350 ? 7.769 244.203 0.601 1.00 88.04 ? 656 ASN A ND2 1 ATOM 5359 H H . ASN A 1 350 ? 11.275 243.903 0.935 1.00 85.78 ? 656 ASN A H 1 ATOM 5360 H HA . ASN A 1 350 ? 10.701 241.538 -0.193 1.00 84.40 ? 656 ASN A HA 1 ATOM 5361 H HB2 . ASN A 1 350 ? 9.696 244.072 -0.939 1.00 82.86 ? 656 ASN A HB2 1 ATOM 5362 H HB3 . ASN A 1 350 ? 9.095 242.672 -1.393 1.00 82.86 ? 656 ASN A HB3 1 ATOM 5363 H HD21 . ASN A 1 350 ? 7.218 244.258 1.259 1.00 105.65 ? 656 ASN A HD21 1 ATOM 5364 H HD22 . ASN A 1 350 ? 7.781 244.816 -0.002 1.00 105.65 ? 656 ASN A HD22 1 ATOM 5365 N N . ILE A 1 351 ? 11.786 241.545 -2.402 1.00 47.74 ? 657 ILE A N 1 ATOM 5366 C CA . ILE A 1 351 ? 12.591 241.543 -3.617 1.00 41.54 ? 657 ILE A CA 1 ATOM 5367 C C . ILE A 1 351 ? 12.038 242.571 -4.595 1.00 37.09 ? 657 ILE A C 1 ATOM 5368 O O . ILE A 1 351 ? 10.848 242.558 -4.930 1.00 41.63 ? 657 ILE A O 1 ATOM 5369 C CB . ILE A 1 351 ? 12.623 240.137 -4.231 1.00 42.68 ? 657 ILE A CB 1 ATOM 5370 C CG1 . ILE A 1 351 ? 13.493 239.225 -3.357 1.00 40.99 ? 657 ILE A CG1 1 ATOM 5371 C CG2 . ILE A 1 351 ? 13.126 240.181 -5.680 1.00 40.09 ? 657 ILE A CG2 1 ATOM 5372 C CD1 . ILE A 1 351 ? 13.735 237.841 -3.940 1.00 52.67 ? 657 ILE A CD1 1 ATOM 5373 H H . ILE A 1 351 ? 11.326 240.828 -2.283 1.00 57.28 ? 657 ILE A H 1 ATOM 5374 H HA . ILE A 1 351 ? 13.501 241.796 -3.396 1.00 49.85 ? 657 ILE A HA 1 ATOM 5375 H HB . ILE A 1 351 ? 11.719 239.785 -4.233 1.00 51.21 ? 657 ILE A HB 1 ATOM 5376 H HG12 . ILE A 1 351 ? 14.357 239.647 -3.232 1.00 49.19 ? 657 ILE A HG12 1 ATOM 5377 H HG13 . ILE A 1 351 ? 13.058 239.110 -2.498 1.00 49.19 ? 657 ILE A HG13 1 ATOM 5378 H HG21 . ILE A 1 351 ? 13.135 239.279 -6.038 1.00 48.11 ? 657 ILE A HG21 1 ATOM 5379 H HG22 . ILE A 1 351 ? 12.531 240.740 -6.204 1.00 48.11 ? 657 ILE A HG22 1 ATOM 5380 H HG23 . ILE A 1 351 ? 14.023 240.550 -5.692 1.00 48.11 ? 657 ILE A HG23 1 ATOM 5381 H HD11 . ILE A 1 351 ? 14.291 237.333 -3.328 1.00 63.21 ? 657 ILE A HD11 1 ATOM 5382 H HD12 . ILE A 1 351 ? 12.882 237.395 -4.060 1.00 63.21 ? 657 ILE A HD12 1 ATOM 5383 H HD13 . ILE A 1 351 ? 14.184 237.933 -4.795 1.00 63.21 ? 657 ILE A HD13 1 ATOM 5384 N N . ILE A 1 352 ? 12.903 243.475 -5.051 1.00 29.25 ? 658 ILE A N 1 ATOM 5385 C CA . ILE A 1 352 ? 12.545 244.478 -6.048 1.00 35.36 ? 658 ILE A CA 1 ATOM 5386 C C . ILE A 1 352 ? 13.387 244.375 -7.312 1.00 36.96 ? 658 ILE A C 1 ATOM 5387 O O . ILE A 1 352 ? 13.235 245.214 -8.210 1.00 27.72 ? 658 ILE A O 1 ATOM 5388 C CB . ILE A 1 352 ? 12.645 245.904 -5.468 1.00 38.51 ? 658 ILE A CB 1 ATOM 5389 C CG1 . ILE A 1 352 ? 14.074 246.172 -4.989 1.00 38.98 ? 658 ILE A CG1 1 ATOM 5390 C CG2 . ILE A 1 352 ? 11.641 246.094 -4.346 1.00 38.55 ? 658 ILE A CG2 1 ATOM 5391 C CD1 . ILE A 1 352 ? 14.298 247.575 -4.488 1.00 36.73 ? 658 ILE A CD1 1 ATOM 5392 H H . ILE A 1 352 ? 13.721 243.528 -4.791 1.00 35.10 ? 658 ILE A H 1 ATOM 5393 H HA . ILE A 1 352 ? 11.620 244.335 -6.304 1.00 42.44 ? 658 ILE A HA 1 ATOM 5394 H HB . ILE A 1 352 ? 12.437 246.536 -6.174 1.00 46.21 ? 658 ILE A HB 1 ATOM 5395 H HG12 . ILE A 1 352 ? 14.278 245.562 -4.263 1.00 46.77 ? 658 ILE A HG12 1 ATOM 5396 H HG13 . ILE A 1 352 ? 14.684 246.020 -5.727 1.00 46.77 ? 658 ILE A HG13 1 ATOM 5397 H HG21 . ILE A 1 352 ? 11.723 246.996 -3.999 1.00 46.25 ? 658 ILE A HG21 1 ATOM 5398 H HG22 . ILE A 1 352 ? 10.747 245.954 -4.696 1.00 46.25 ? 658 ILE A HG22 1 ATOM 5399 H HG23 . ILE A 1 352 ? 11.827 245.451 -3.644 1.00 46.25 ? 658 ILE A HG23 1 ATOM 5400 H HD11 . ILE A 1 352 ? 15.221 247.665 -4.204 1.00 44.08 ? 658 ILE A HD11 1 ATOM 5401 H HD12 . ILE A 1 352 ? 14.110 248.200 -5.206 1.00 44.08 ? 658 ILE A HD12 1 ATOM 5402 H HD13 . ILE A 1 352 ? 13.703 247.742 -3.740 1.00 44.08 ? 658 ILE A HD13 1 ATOM 5403 N N . GLY A 1 353 ? 14.266 243.378 -7.416 1.00 29.71 ? 659 GLY A N 1 ATOM 5404 C CA . GLY A 1 353 ? 15.211 243.325 -8.513 1.00 32.32 ? 659 GLY A CA 1 ATOM 5405 C C . GLY A 1 353 ? 15.944 242.005 -8.559 1.00 34.08 ? 659 GLY A C 1 ATOM 5406 O O . GLY A 1 353 ? 16.006 241.263 -7.571 1.00 30.14 ? 659 GLY A O 1 ATOM 5407 H H . GLY A 1 353 ? 14.331 242.724 -6.861 1.00 35.65 ? 659 GLY A H 1 ATOM 5408 H HA2 . GLY A 1 353 ? 14.742 243.448 -9.353 1.00 38.79 ? 659 GLY A HA2 1 ATOM 5409 H HA3 . GLY A 1 353 ? 15.863 244.038 -8.416 1.00 38.79 ? 659 GLY A HA3 1 ATOM 5410 N N . PHE A 1 354 ? 16.536 241.741 -9.718 1.00 24.32 ? 660 PHE A N 1 ATOM 5411 C CA . PHE A 1 354 ? 17.106 240.436 -9.992 1.00 33.81 ? 660 PHE A CA 1 ATOM 5412 C C . PHE A 1 354 ? 18.161 240.569 -11.080 1.00 35.24 ? 660 PHE A C 1 ATOM 5413 O O . PHE A 1 354 ? 17.970 241.313 -12.047 1.00 27.83 ? 660 PHE A O 1 ATOM 5414 C CB . PHE A 1 354 ? 15.962 239.480 -10.376 1.00 31.00 ? 660 PHE A CB 1 ATOM 5415 C CG . PHE A 1 354 ? 16.305 238.463 -11.389 1.00 26.95 ? 660 PHE A CG 1 ATOM 5416 C CD1 . PHE A 1 354 ? 17.236 237.480 -11.120 1.00 32.96 ? 660 PHE A CD1 1 ATOM 5417 C CD2 . PHE A 1 354 ? 15.633 238.444 -12.598 1.00 29.03 ? 660 PHE A CD2 1 ATOM 5418 C CE1 . PHE A 1 354 ? 17.528 236.519 -12.059 1.00 35.59 ? 660 PHE A CE1 1 ATOM 5419 C CE2 . PHE A 1 354 ? 15.907 237.491 -13.545 1.00 29.24 ? 660 PHE A CE2 1 ATOM 5420 C CZ . PHE A 1 354 ? 16.857 236.518 -13.282 1.00 35.55 ? 660 PHE A CZ 1 ATOM 5421 H H . PHE A 1 354 ? 16.619 242.304 -10.363 1.00 29.18 ? 660 PHE A H 1 ATOM 5422 H HA . PHE A 1 354 ? 17.533 240.096 -9.190 1.00 40.58 ? 660 PHE A HA 1 ATOM 5423 H HB2 . PHE A 1 354 ? 15.672 239.011 -9.578 1.00 37.20 ? 660 PHE A HB2 1 ATOM 5424 H HB3 . PHE A 1 354 ? 15.227 240.006 -10.728 1.00 37.20 ? 660 PHE A HB3 1 ATOM 5425 H HD1 . PHE A 1 354 ? 17.684 237.480 -10.305 1.00 39.56 ? 660 PHE A HD1 1 ATOM 5426 H HD2 . PHE A 1 354 ? 14.995 239.097 -12.777 1.00 34.83 ? 660 PHE A HD2 1 ATOM 5427 H HE1 . PHE A 1 354 ? 18.166 235.867 -11.877 1.00 42.71 ? 660 PHE A HE1 1 ATOM 5428 H HE2 . PHE A 1 354 ? 15.458 237.499 -14.360 1.00 35.08 ? 660 PHE A HE2 1 ATOM 5429 H HZ . PHE A 1 354 ? 17.052 235.871 -13.921 1.00 42.66 ? 660 PHE A HZ 1 ATOM 5430 N N . LYS A 1 355 ? 19.285 239.882 -10.884 1.00 32.43 ? 661 LYS A N 1 ATOM 5431 C CA . LYS A 1 355 ? 20.322 239.747 -11.898 1.00 36.94 ? 661 LYS A CA 1 ATOM 5432 C C . LYS A 1 355 ? 20.427 238.292 -12.326 1.00 38.23 ? 661 LYS A C 1 ATOM 5433 O O . LYS A 1 355 ? 20.611 237.398 -11.490 1.00 34.19 ? 661 LYS A O 1 ATOM 5434 C CB . LYS A 1 355 ? 21.679 240.230 -11.384 1.00 42.85 ? 661 LYS A CB 1 ATOM 5435 C CG . LYS A 1 355 ? 22.766 240.217 -12.456 1.00 44.34 ? 661 LYS A CG 1 ATOM 5436 C CD . LYS A 1 355 ? 23.867 241.234 -12.176 1.00 48.10 ? 661 LYS A CD 1 ATOM 5437 C CE . LYS A 1 355 ? 24.996 240.640 -11.359 1.00 73.46 ? 661 LYS A CE 1 ATOM 5438 N NZ . LYS A 1 355 ? 25.947 241.697 -10.901 1.00 82.19 ? 661 LYS A NZ 1 ATOM 5439 H H . LYS A 1 355 ? 19.471 239.475 -10.151 1.00 38.91 ? 661 LYS A H 1 ATOM 5440 H HA . LYS A 1 355 ? 20.083 240.277 -12.674 1.00 44.33 ? 661 LYS A HA 1 ATOM 5441 H HB2 . LYS A 1 355 ? 21.588 241.140 -11.062 1.00 51.42 ? 661 LYS A HB2 1 ATOM 5442 H HB3 . LYS A 1 355 ? 21.966 239.650 -10.661 1.00 51.42 ? 661 LYS A HB3 1 ATOM 5443 H HG2 . LYS A 1 355 ? 23.171 239.336 -12.487 1.00 53.21 ? 661 LYS A HG2 1 ATOM 5444 H HG3 . LYS A 1 355 ? 22.368 240.432 -13.314 1.00 53.21 ? 661 LYS A HG3 1 ATOM 5445 H HD2 . LYS A 1 355 ? 24.234 241.545 -13.018 1.00 57.71 ? 661 LYS A HD2 1 ATOM 5446 H HD3 . LYS A 1 355 ? 23.493 241.979 -11.679 1.00 57.71 ? 661 LYS A HD3 1 ATOM 5447 H HE2 . LYS A 1 355 ? 24.629 240.200 -10.576 1.00 88.15 ? 661 LYS A HE2 1 ATOM 5448 H HE3 . LYS A 1 355 ? 25.487 240.004 -11.904 1.00 88.15 ? 661 LYS A HE3 1 ATOM 5449 H HZ1 . LYS A 1 355 ? 26.602 241.331 -10.424 1.00 98.62 ? 661 LYS A HZ1 1 ATOM 5450 H HZ2 . LYS A 1 355 ? 26.299 242.114 -11.604 1.00 98.62 ? 661 LYS A HZ2 1 ATOM 5451 H HZ3 . LYS A 1 355 ? 25.519 242.293 -10.396 1.00 98.62 ? 661 LYS A HZ3 1 ATOM 5452 N N . ASP A 1 356 ? 20.326 238.068 -13.627 1.00 38.57 ? 662 ASP A N 1 ATOM 5453 C CA . ASP A 1 356 ? 20.275 236.726 -14.200 1.00 38.55 ? 662 ASP A CA 1 ATOM 5454 C C . ASP A 1 356 ? 21.694 236.278 -14.521 1.00 40.37 ? 662 ASP A C 1 ATOM 5455 O O . ASP A 1 356 ? 22.358 236.863 -15.376 1.00 42.57 ? 662 ASP A O 1 ATOM 5456 C CB . ASP A 1 356 ? 19.405 236.721 -15.452 1.00 38.96 ? 662 ASP A CB 1 ATOM 5457 C CG . ASP A 1 356 ? 19.175 235.344 -15.992 1.00 37.53 ? 662 ASP A CG 1 ATOM 5458 O OD1 . ASP A 1 356 ? 19.775 234.393 -15.450 1.00 36.92 ? 662 ASP A OD1 1 ATOM 5459 O OD2 . ASP A 1 356 ? 18.398 235.217 -16.965 1.00 36.63 ? 662 ASP A OD2 1 ATOM 5460 H H . ASP A 1 356 ? 20.285 238.692 -14.217 1.00 46.28 ? 662 ASP A H 1 ATOM 5461 H HA . ASP A 1 356 ? 19.894 236.110 -13.554 1.00 46.27 ? 662 ASP A HA 1 ATOM 5462 H HB2 . ASP A 1 356 ? 18.541 237.107 -15.239 1.00 46.75 ? 662 ASP A HB2 1 ATOM 5463 H HB3 . ASP A 1 356 ? 19.841 237.244 -16.143 1.00 46.75 ? 662 ASP A HB3 1 ATOM 5464 N N . PHE A 1 357 ? 22.165 235.239 -13.835 1.00 50.24 ? 663 PHE A N 1 ATOM 5465 C CA . PHE A 1 357 ? 23.521 234.764 -14.073 1.00 42.29 ? 663 PHE A CA 1 ATOM 5466 C C . PHE A 1 357 ? 23.686 234.176 -15.463 1.00 39.49 ? 663 PHE A C 1 ATOM 5467 O O . PHE A 1 357 ? 24.809 234.134 -15.974 1.00 50.57 ? 663 PHE A O 1 ATOM 5468 C CB . PHE A 1 357 ? 23.908 233.725 -13.015 1.00 43.96 ? 663 PHE A CB 1 ATOM 5469 C CG . PHE A 1 357 ? 23.274 232.371 -13.223 1.00 46.28 ? 663 PHE A CG 1 ATOM 5470 C CD1 . PHE A 1 357 ? 23.895 231.408 -14.016 1.00 46.03 ? 663 PHE A CD1 1 ATOM 5471 C CD2 . PHE A 1 357 ? 22.063 232.056 -12.621 1.00 47.40 ? 663 PHE A CD2 1 ATOM 5472 C CE1 . PHE A 1 357 ? 23.320 230.147 -14.204 1.00 48.40 ? 663 PHE A CE1 1 ATOM 5473 C CE2 . PHE A 1 357 ? 21.482 230.797 -12.801 1.00 55.62 ? 663 PHE A CE2 1 ATOM 5474 C CZ . PHE A 1 357 ? 22.115 229.841 -13.599 1.00 53.47 ? 663 PHE A CZ 1 ATOM 5475 H H . PHE A 1 357 ? 21.728 234.801 -13.237 1.00 60.29 ? 663 PHE A H 1 ATOM 5476 H HA . PHE A 1 357 ? 24.133 235.512 -13.992 1.00 50.74 ? 663 PHE A HA 1 ATOM 5477 H HB2 . PHE A 1 357 ? 24.871 233.606 -13.032 1.00 52.76 ? 663 PHE A HB2 1 ATOM 5478 H HB3 . PHE A 1 357 ? 23.633 234.049 -12.143 1.00 52.76 ? 663 PHE A HB3 1 ATOM 5479 H HD1 . PHE A 1 357 ? 24.708 231.606 -14.423 1.00 55.24 ? 663 PHE A HD1 1 ATOM 5480 H HD2 . PHE A 1 357 ? 21.638 232.686 -12.085 1.00 56.88 ? 663 PHE A HD2 1 ATOM 5481 H HE1 . PHE A 1 357 ? 23.747 229.516 -14.737 1.00 58.08 ? 663 PHE A HE1 1 ATOM 5482 H HE2 . PHE A 1 357 ? 20.670 230.598 -12.394 1.00 66.75 ? 663 PHE A HE2 1 ATOM 5483 H HZ . PHE A 1 357 ? 21.727 229.005 -13.725 1.00 64.17 ? 663 PHE A HZ 1 ATOM 5484 N N . VAL A 1 358 ? 22.601 233.716 -16.091 1.00 39.89 ? 664 VAL A N 1 ATOM 5485 C CA . VAL A 1 358 ? 22.727 233.095 -17.409 1.00 44.89 ? 664 VAL A CA 1 ATOM 5486 C C . VAL A 1 358 ? 23.052 234.149 -18.467 1.00 44.82 ? 664 VAL A C 1 ATOM 5487 O O . VAL A 1 358 ? 23.885 233.924 -19.352 1.00 48.48 ? 664 VAL A O 1 ATOM 5488 C CB . VAL A 1 358 ? 21.445 232.307 -17.758 1.00 48.19 ? 664 VAL A CB 1 ATOM 5489 C CG1 . VAL A 1 358 ? 21.536 231.682 -19.173 1.00 39.41 ? 664 VAL A CG1 1 ATOM 5490 C CG2 . VAL A 1 358 ? 21.170 231.217 -16.707 1.00 42.43 ? 664 VAL A CG2 1 ATOM 5491 H H . VAL A 1 358 ? 21.799 233.751 -15.783 1.00 47.87 ? 664 VAL A H 1 ATOM 5492 H HA . VAL A 1 358 ? 23.464 232.464 -17.386 1.00 53.87 ? 664 VAL A HA 1 ATOM 5493 H HB . VAL A 1 358 ? 20.692 232.919 -17.753 1.00 57.83 ? 664 VAL A HB 1 ATOM 5494 H HG11 . VAL A 1 358 ? 20.716 231.197 -19.357 1.00 47.29 ? 664 VAL A HG11 1 ATOM 5495 H HG12 . VAL A 1 358 ? 21.655 232.391 -19.824 1.00 47.29 ? 664 VAL A HG12 1 ATOM 5496 H HG13 . VAL A 1 358 ? 22.293 231.076 -19.202 1.00 47.29 ? 664 VAL A HG13 1 ATOM 5497 H HG21 . VAL A 1 358 ? 20.361 230.740 -16.951 1.00 50.92 ? 664 VAL A HG21 1 ATOM 5498 H HG22 . VAL A 1 358 ? 21.922 230.605 -16.684 1.00 50.92 ? 664 VAL A HG22 1 ATOM 5499 H HG23 . VAL A 1 358 ? 21.058 231.637 -15.839 1.00 50.92 ? 664 VAL A HG23 1 ATOM 5500 N N . THR A 1 359 ? 22.417 235.316 -18.380 1.00 43.59 ? 665 THR A N 1 ATOM 5501 C CA . THR A 1 359 ? 22.547 236.370 -19.377 1.00 39.69 ? 665 THR A CA 1 ATOM 5502 C C . THR A 1 359 ? 23.263 237.615 -18.866 1.00 39.58 ? 665 THR A C 1 ATOM 5503 O O . THR A 1 359 ? 23.620 238.479 -19.675 1.00 43.32 ? 665 THR A O 1 ATOM 5504 C CB . THR A 1 359 ? 21.154 236.777 -19.872 1.00 37.41 ? 665 THR A CB 1 ATOM 5505 O OG1 . THR A 1 359 ? 20.382 237.266 -18.763 1.00 36.20 ? 665 THR A OG1 1 ATOM 5506 C CG2 . THR A 1 359 ? 20.453 235.589 -20.493 1.00 32.60 ? 665 THR A CG2 1 ATOM 5507 H H . THR A 1 359 ? 21.890 235.524 -17.733 1.00 52.30 ? 665 THR A H 1 ATOM 5508 H HA . THR A 1 359 ? 23.047 236.027 -20.135 1.00 47.63 ? 665 THR A HA 1 ATOM 5509 H HB . THR A 1 359 ? 21.237 237.473 -20.543 1.00 44.90 ? 665 THR A HB 1 ATOM 5510 H HG1 . THR A 1 359 ? 19.616 237.492 -19.023 1.00 43.45 ? 665 THR A HG1 1 ATOM 5511 H HG21 . THR A 1 359 ? 19.572 235.851 -20.805 1.00 39.12 ? 665 THR A HG21 1 ATOM 5512 H HG22 . THR A 1 359 ? 20.968 235.256 -21.245 1.00 39.12 ? 665 THR A HG22 1 ATOM 5513 H HG23 . THR A 1 359 ? 20.358 234.881 -19.838 1.00 39.12 ? 665 THR A HG23 1 ATOM 5514 N N . ASN A 1 360 ? 23.470 237.737 -17.557 1.00 39.38 ? 666 ASN A N 1 ATOM 5515 C CA . ASN A 1 360 ? 23.964 238.947 -16.902 1.00 43.78 ? 666 ASN A CA 1 ATOM 5516 C C . ASN A 1 360 ? 22.992 240.111 -17.029 1.00 39.84 ? 666 ASN A C 1 ATOM 5517 O O . ASN A 1 360 ? 23.353 241.255 -16.723 1.00 43.14 ? 666 ASN A O 1 ATOM 5518 C CB . ASN A 1 360 ? 25.340 239.368 -17.431 1.00 45.11 ? 666 ASN A CB 1 ATOM 5519 C CG . ASN A 1 360 ? 26.474 238.652 -16.726 1.00 64.89 ? 666 ASN A CG 1 ATOM 5520 O OD1 . ASN A 1 360 ? 26.478 238.528 -15.494 1.00 64.56 ? 666 ASN A OD1 1 ATOM 5521 N ND2 . ASN A 1 360 ? 27.438 238.161 -17.502 1.00 64.52 ? 666 ASN A ND2 1 ATOM 5522 H H . ASN A 1 360 ? 23.322 237.098 -17.000 1.00 47.26 ? 666 ASN A H 1 ATOM 5523 H HA . ASN A 1 360 ? 24.065 238.760 -15.956 1.00 52.54 ? 666 ASN A HA 1 ATOM 5524 H HB2 . ASN A 1 360 ? 25.393 239.159 -18.377 1.00 54.13 ? 666 ASN A HB2 1 ATOM 5525 H HB3 . ASN A 1 360 ? 25.454 240.321 -17.294 1.00 54.13 ? 666 ASN A HB3 1 ATOM 5526 H HD21 . ASN A 1 360 ? 28.104 237.746 -17.150 1.00 77.43 ? 666 ASN A HD21 1 ATOM 5527 H HD22 . ASN A 1 360 ? 27.395 238.259 -18.356 1.00 77.43 ? 666 ASN A HD22 1 ATOM 5528 N N . LYS A 1 361 ? 21.763 239.857 -17.454 1.00 36.28 ? 667 LYS A N 1 ATOM 5529 C CA . LYS A 1 361 ? 20.794 240.927 -17.568 1.00 26.53 ? 667 LYS A CA 1 ATOM 5530 C C . LYS A 1 361 ? 20.221 241.238 -16.200 1.00 35.38 ? 667 LYS A C 1 ATOM 5531 O O . LYS A 1 361 ? 20.131 240.367 -15.322 1.00 25.83 ? 667 LYS A O 1 ATOM 5532 C CB . LYS A 1 361 ? 19.670 240.559 -18.538 1.00 31.03 ? 667 LYS A CB 1 ATOM 5533 C CG . LYS A 1 361 ? 20.101 240.438 -20.000 1.00 29.44 ? 667 LYS A CG 1 ATOM 5534 C CD . LYS A 1 361 ? 18.902 240.041 -20.869 1.00 37.60 ? 667 LYS A CD 1 ATOM 5535 C CE . LYS A 1 361 ? 19.265 239.827 -22.347 1.00 37.45 ? 667 LYS A CE 1 ATOM 5536 N NZ . LYS A 1 361 ? 19.511 241.100 -23.076 1.00 43.60 ? 667 LYS A NZ 1 ATOM 5537 H H . LYS A 1 361 ? 21.470 239.080 -17.680 1.00 43.54 ? 667 LYS A H 1 ATOM 5538 H HA . LYS A 1 361 ? 21.235 241.724 -17.902 1.00 31.84 ? 667 LYS A HA 1 ATOM 5539 H HB2 . LYS A 1 361 ? 19.298 239.705 -18.270 1.00 37.23 ? 667 LYS A HB2 1 ATOM 5540 H HB3 . LYS A 1 361 ? 18.984 241.243 -18.490 1.00 37.23 ? 667 LYS A HB3 1 ATOM 5541 H HG2 . LYS A 1 361 ? 20.438 241.293 -20.311 1.00 35.33 ? 667 LYS A HG2 1 ATOM 5542 H HG3 . LYS A 1 361 ? 20.782 239.752 -20.082 1.00 35.33 ? 667 LYS A HG3 1 ATOM 5543 H HD2 . LYS A 1 361 ? 18.529 239.212 -20.531 1.00 45.12 ? 667 LYS A HD2 1 ATOM 5544 H HD3 . LYS A 1 361 ? 18.235 240.744 -20.825 1.00 45.12 ? 667 LYS A HD3 1 ATOM 5545 H HE2 . LYS A 1 361 ? 20.072 239.291 -22.399 1.00 44.93 ? 667 LYS A HE2 1 ATOM 5546 H HE3 . LYS A 1 361 ? 18.533 239.367 -22.788 1.00 44.93 ? 667 LYS A HE3 1 ATOM 5547 H HZ1 . LYS A 1 361 ? 19.717 240.929 -23.925 1.00 52.32 ? 667 LYS A HZ1 1 ATOM 5548 H HZ2 . LYS A 1 361 ? 18.782 241.610 -23.053 1.00 52.32 ? 667 LYS A HZ2 1 ATOM 5549 H HZ3 . LYS A 1 361 ? 20.185 241.541 -22.698 1.00 52.32 ? 667 LYS A HZ3 1 ATOM 5550 N N . THR A 1 362 ? 19.858 242.502 -16.024 1.00 25.67 ? 668 THR A N 1 ATOM 5551 C CA . THR A 1 362 ? 19.303 243.013 -14.788 1.00 16.68 ? 668 THR A CA 1 ATOM 5552 C C . THR A 1 362 ? 17.861 243.439 -15.009 1.00 24.16 ? 668 THR A C 1 ATOM 5553 O O . THR A 1 362 ? 17.493 243.923 -16.085 1.00 26.09 ? 668 THR A O 1 ATOM 5554 C CB . THR A 1 362 ? 20.126 244.188 -14.266 1.00 20.95 ? 668 THR A CB 1 ATOM 5555 O OG1 . THR A 1 362 ? 20.560 244.997 -15.366 1.00 26.66 ? 668 THR A OG1 1 ATOM 5556 C CG2 . THR A 1 362 ? 21.345 243.682 -13.500 1.00 30.04 ? 668 THR A CG2 1 ATOM 5557 H H . THR A 1 362 ? 19.929 243.103 -16.635 1.00 30.81 ? 668 THR A H 1 ATOM 5558 H HA . THR A 1 362 ? 19.314 242.312 -14.118 1.00 20.02 ? 668 THR A HA 1 ATOM 5559 H HB . THR A 1 362 ? 19.584 244.722 -13.664 1.00 25.14 ? 668 THR A HB 1 ATOM 5560 H HG1 . THR A 1 362 ? 19.894 245.291 -15.786 1.00 31.99 ? 668 THR A HG1 1 ATOM 5561 H HG21 . THR A 1 362 ? 21.864 244.432 -13.171 1.00 36.05 ? 668 THR A HG21 1 ATOM 5562 H HG22 . THR A 1 362 ? 21.062 243.139 -12.747 1.00 36.05 ? 668 THR A HG22 1 ATOM 5563 H HG23 . THR A 1 362 ? 21.903 243.144 -14.084 1.00 36.05 ? 668 THR A HG23 1 ATOM 5564 N N . TYR A 1 363 ? 17.047 243.240 -13.977 1.00 26.99 ? 669 TYR A N 1 ATOM 5565 C CA . TYR A 1 363 ? 15.618 243.493 -14.039 1.00 26.95 ? 669 TYR A CA 1 ATOM 5566 C C . TYR A 1 363 ? 15.157 244.144 -12.751 1.00 24.67 ? 669 TYR A C 1 ATOM 5567 O O . TYR A 1 363 ? 15.671 243.835 -11.673 1.00 23.38 ? 669 TYR A O 1 ATOM 5568 C CB . TYR A 1 363 ? 14.822 242.199 -14.235 1.00 25.67 ? 669 TYR A CB 1 ATOM 5569 C CG . TYR A 1 363 ? 15.222 241.400 -15.434 1.00 26.93 ? 669 TYR A CG 1 ATOM 5570 C CD1 . TYR A 1 363 ? 16.339 240.567 -15.402 1.00 24.49 ? 669 TYR A CD1 1 ATOM 5571 C CD2 . TYR A 1 363 ? 14.473 241.463 -16.604 1.00 28.39 ? 669 TYR A CD2 1 ATOM 5572 C CE1 . TYR A 1 363 ? 16.703 239.828 -16.506 1.00 27.24 ? 669 TYR A CE1 1 ATOM 5573 C CE2 . TYR A 1 363 ? 14.831 240.725 -17.718 1.00 26.64 ? 669 TYR A CE2 1 ATOM 5574 C CZ . TYR A 1 363 ? 15.943 239.907 -17.663 1.00 24.74 ? 669 TYR A CZ 1 ATOM 5575 O OH . TYR A 1 363 ? 16.302 239.176 -18.774 1.00 31.79 ? 669 TYR A OH 1 ATOM 5576 H H . TYR A 1 363 ? 17.309 242.951 -13.211 1.00 32.38 ? 669 TYR A H 1 ATOM 5577 H HA . TYR A 1 363 ? 15.424 244.092 -14.777 1.00 32.34 ? 669 TYR A HA 1 ATOM 5578 H HB2 . TYR A 1 363 ? 14.945 241.638 -13.453 1.00 30.80 ? 669 TYR A HB2 1 ATOM 5579 H HB3 . TYR A 1 363 ? 13.883 242.424 -14.331 1.00 30.80 ? 669 TYR A HB3 1 ATOM 5580 H HD1 . TYR A 1 363 ? 16.848 240.513 -14.626 1.00 29.39 ? 669 TYR A HD1 1 ATOM 5581 H HD2 . TYR A 1 363 ? 13.724 242.012 -16.640 1.00 34.07 ? 669 TYR A HD2 1 ATOM 5582 H HE1 . TYR A 1 363 ? 17.452 239.278 -16.475 1.00 32.68 ? 669 TYR A HE1 1 ATOM 5583 H HE2 . TYR A 1 363 ? 14.325 240.776 -18.496 1.00 31.96 ? 669 TYR A HE2 1 ATOM 5584 H HH . TYR A 1 363 ? 16.996 238.730 -18.612 1.00 38.15 ? 669 TYR A HH 1 ATOM 5585 N N . ASN A 1 364 ? 14.193 245.049 -12.881 1.00 24.64 ? 670 ASN A N 1 ATOM 5586 C CA . ASN A 1 364 ? 13.358 245.436 -11.759 1.00 24.83 ? 670 ASN A CA 1 ATOM 5587 C C . ASN A 1 364 ? 12.225 244.435 -11.631 1.00 30.53 ? 670 ASN A C 1 ATOM 5588 O O . ASN A 1 364 ? 11.797 243.819 -12.617 1.00 32.40 ? 670 ASN A O 1 ATOM 5589 C CB . ASN A 1 364 ? 12.769 246.834 -11.942 1.00 28.97 ? 670 ASN A CB 1 ATOM 5590 C CG . ASN A 1 364 ? 13.796 247.933 -11.765 1.00 32.87 ? 670 ASN A CG 1 ATOM 5591 O OD1 . ASN A 1 364 ? 14.851 247.726 -11.170 1.00 35.24 ? 670 ASN A OD1 1 ATOM 5592 N ND2 . ASN A 1 364 ? 13.491 249.113 -12.289 1.00 36.27 ? 670 ASN A ND2 1 ATOM 5593 H H . ASN A 1 364 ? 14.002 245.454 -13.615 1.00 29.57 ? 670 ASN A H 1 ATOM 5594 H HA . ASN A 1 364 ? 13.880 245.422 -10.942 1.00 29.80 ? 670 ASN A HA 1 ATOM 5595 H HB2 . ASN A 1 364 ? 12.403 246.908 -12.838 1.00 34.77 ? 670 ASN A HB2 1 ATOM 5596 H HB3 . ASN A 1 364 ? 12.068 246.970 -11.286 1.00 34.77 ? 670 ASN A HB3 1 ATOM 5597 H HD21 . ASN A 1 364 ? 14.040 249.771 -12.217 1.00 43.53 ? 670 ASN A HD21 1 ATOM 5598 H HD22 . ASN A 1 364 ? 12.744 249.220 -12.703 1.00 43.53 ? 670 ASN A HD22 1 ATOM 5599 N N . ILE A 1 365 ? 11.746 244.266 -10.405 1.00 25.26 ? 671 ILE A N 1 ATOM 5600 C CA . ILE A 1 365 ? 10.565 243.463 -10.141 1.00 30.28 ? 671 ILE A CA 1 ATOM 5601 C C . ILE A 1 365 ? 9.573 244.353 -9.415 1.00 28.98 ? 671 ILE A C 1 ATOM 5602 O O . ILE A 1 365 ? 9.911 244.953 -8.389 1.00 31.55 ? 671 ILE A O 1 ATOM 5603 C CB . ILE A 1 365 ? 10.901 242.203 -9.331 1.00 35.17 ? 671 ILE A CB 1 ATOM 5604 C CG1 . ILE A 1 365 ? 11.952 241.378 -10.074 1.00 30.64 ? 671 ILE A CG1 1 ATOM 5605 C CG2 . ILE A 1 365 ? 9.651 241.380 -9.114 1.00 37.86 ? 671 ILE A CG2 1 ATOM 5606 C CD1 . ILE A 1 365 ? 12.486 240.194 -9.296 1.00 32.56 ? 671 ILE A CD1 1 ATOM 5607 H H . ILE A 1 365 ? 12.094 244.613 -9.699 1.00 30.31 ? 671 ILE A H 1 ATOM 5608 H HA . ILE A 1 365 ? 10.169 243.188 -10.983 1.00 36.34 ? 671 ILE A HA 1 ATOM 5609 H HB . ILE A 1 365 ? 11.259 242.468 -8.469 1.00 42.21 ? 671 ILE A HB 1 ATOM 5610 H HG12 . ILE A 1 365 ? 11.558 241.038 -10.893 1.00 36.77 ? 671 ILE A HG12 1 ATOM 5611 H HG13 . ILE A 1 365 ? 12.704 241.953 -10.287 1.00 36.77 ? 671 ILE A HG13 1 ATOM 5612 H HG21 . ILE A 1 365 ? 9.879 240.589 -8.601 1.00 45.43 ? 671 ILE A HG21 1 ATOM 5613 H HG22 . ILE A 1 365 ? 9.003 241.914 -8.628 1.00 45.43 ? 671 ILE A HG22 1 ATOM 5614 H HG23 . ILE A 1 365 ? 9.289 241.123 -9.976 1.00 45.43 ? 671 ILE A HG23 1 ATOM 5615 H HD11 . ILE A 1 365 ? 13.143 239.731 -9.839 1.00 39.07 ? 671 ILE A HD11 1 ATOM 5616 H HD12 . ILE A 1 365 ? 12.899 240.514 -8.479 1.00 39.07 ? 671 ILE A HD12 1 ATOM 5617 H HD13 . ILE A 1 365 ? 11.751 239.598 -9.085 1.00 39.07 ? 671 ILE A HD13 1 ATOM 5618 N N . PHE A 1 366 ? 8.360 244.466 -9.969 1.00 33.15 ? 672 PHE A N 1 ATOM 5619 C CA . PHE A 1 366 ? 7.274 245.228 -9.374 1.00 35.32 ? 672 PHE A CA 1 ATOM 5620 C C . PHE A 1 366 ? 6.143 244.292 -8.964 1.00 37.62 ? 672 PHE A C 1 ATOM 5621 O O . PHE A 1 366 ? 5.976 243.224 -9.560 1.00 37.42 ? 672 PHE A O 1 ATOM 5622 C CB . PHE A 1 366 ? 6.707 246.274 -10.343 1.00 39.83 ? 672 PHE A CB 1 ATOM 5623 C CG . PHE A 1 366 ? 7.714 247.257 -10.834 1.00 35.95 ? 672 PHE A CG 1 ATOM 5624 C CD1 . PHE A 1 366 ? 7.978 248.406 -10.118 1.00 30.61 ? 672 PHE A CD1 1 ATOM 5625 C CD2 . PHE A 1 366 ? 8.389 247.041 -12.025 1.00 38.06 ? 672 PHE A CD2 1 ATOM 5626 C CE1 . PHE A 1 366 ? 8.902 249.329 -10.570 1.00 34.13 ? 672 PHE A CE1 1 ATOM 5627 C CE2 . PHE A 1 366 ? 9.321 247.967 -12.492 1.00 42.15 ? 672 PHE A CE2 1 ATOM 5628 C CZ . PHE A 1 366 ? 9.576 249.113 -11.761 1.00 37.42 ? 672 PHE A CZ 1 ATOM 5629 H H . PHE A 1 366 ? 8.144 244.095 -10.714 1.00 39.78 ? 672 PHE A H 1 ATOM 5630 H HA . PHE A 1 366 ? 7.597 245.685 -8.582 1.00 42.38 ? 672 PHE A HA 1 ATOM 5631 H HB2 . PHE A 1 366 ? 6.340 245.817 -11.115 1.00 47.80 ? 672 PHE A HB2 1 ATOM 5632 H HB3 . PHE A 1 366 ? 6.006 246.770 -9.891 1.00 47.80 ? 672 PHE A HB3 1 ATOM 5633 H HD1 . PHE A 1 366 ? 7.528 248.562 -9.318 1.00 36.73 ? 672 PHE A HD1 1 ATOM 5634 H HD2 . PHE A 1 366 ? 8.216 246.272 -12.520 1.00 45.67 ? 672 PHE A HD2 1 ATOM 5635 H HE1 . PHE A 1 366 ? 9.070 250.098 -10.075 1.00 40.95 ? 672 PHE A HE1 1 ATOM 5636 H HE2 . PHE A 1 366 ? 9.772 247.813 -13.291 1.00 50.58 ? 672 PHE A HE2 1 ATOM 5637 H HZ . PHE A 1 366 ? 10.200 249.732 -12.064 1.00 44.91 ? 672 PHE A HZ 1 ATOM 5638 N N . PRO A 1 367 ? 5.347 244.662 -7.961 1.00 41.71 ? 673 PRO A N 1 ATOM 5639 C CA . PRO A 1 367 ? 4.208 243.820 -7.580 1.00 40.87 ? 673 PRO A CA 1 ATOM 5640 C C . PRO A 1 367 ? 3.109 243.862 -8.630 1.00 49.23 ? 673 PRO A C 1 ATOM 5641 O O . PRO A 1 367 ? 3.001 244.799 -9.427 1.00 46.41 ? 673 PRO A O 1 ATOM 5642 C CB . PRO A 1 367 ? 3.742 244.423 -6.250 1.00 40.43 ? 673 PRO A CB 1 ATOM 5643 C CG . PRO A 1 367 ? 4.237 245.822 -6.270 1.00 36.44 ? 673 PRO A CG 1 ATOM 5644 C CD . PRO A 1 367 ? 5.524 245.799 -7.038 1.00 40.11 ? 673 PRO A CD 1 ATOM 5645 H HA . PRO A 1 367 ? 4.492 242.903 -7.441 1.00 49.05 ? 673 PRO A HA 1 ATOM 5646 H HB2 . PRO A 1 367 ? 2.774 244.401 -6.203 1.00 48.52 ? 673 PRO A HB2 1 ATOM 5647 H HB3 . PRO A 1 367 ? 4.134 243.930 -5.512 1.00 48.52 ? 673 PRO A HB3 1 ATOM 5648 H HG2 . PRO A 1 367 ? 3.586 246.389 -6.713 1.00 43.72 ? 673 PRO A HG2 1 ATOM 5649 H HG3 . PRO A 1 367 ? 4.389 246.125 -5.361 1.00 43.72 ? 673 PRO A HG3 1 ATOM 5650 H HD2 . PRO A 1 367 ? 5.637 246.624 -7.536 1.00 48.13 ? 673 PRO A HD2 1 ATOM 5651 H HD3 . PRO A 1 367 ? 6.272 245.637 -6.442 1.00 48.13 ? 673 PRO A HD3 1 ATOM 5652 N N . CYS A 1 368 ? 2.285 242.814 -8.623 1.00 48.39 ? 674 CYS A N 1 ATOM 5653 C CA . CYS A 1 368 ? 1.257 242.627 -9.650 1.00 48.39 ? 674 CYS A CA 1 ATOM 5654 C C . CYS A 1 368 ? 0.040 243.535 -9.452 1.00 50.35 ? 674 CYS A C 1 ATOM 5655 O O . CYS A 1 368 ? -0.288 243.922 -8.328 1.00 56.02 ? 674 CYS A O 1 ATOM 5656 C CB . CYS A 1 368 ? 0.813 241.166 -9.674 1.00 52.48 ? 674 CYS A CB 1 ATOM 5657 S SG . CYS A 1 368 ? 2.128 240.020 -10.150 1.00 55.32 ? 674 CYS A SG 1 ATOM 5658 H H . CYS A 1 368 ? 2.301 242.192 -8.030 1.00 58.07 ? 674 CYS A H 1 ATOM 5659 H HA . CYS A 1 368 ? 1.641 242.833 -10.517 1.00 58.07 ? 674 CYS A HA 1 ATOM 5660 H HB2 . CYS A 1 368 ? 0.508 240.917 -8.787 1.00 62.98 ? 674 CYS A HB2 1 ATOM 5661 H HB3 . CYS A 1 368 ? 0.089 241.068 -10.311 1.00 62.98 ? 674 CYS A HB3 1 HETATM 5662 C C1 . NAG B 2 . ? 37.946 196.142 1.567 1.00 57.36 ? 701 NAG A C1 1 HETATM 5663 C C2 . NAG B 2 . ? 38.778 197.260 0.930 1.00 59.02 ? 701 NAG A C2 1 HETATM 5664 C C3 . NAG B 2 . ? 39.930 196.665 0.122 1.00 64.92 ? 701 NAG A C3 1 HETATM 5665 C C4 . NAG B 2 . ? 40.752 195.710 0.979 1.00 65.00 ? 701 NAG A C4 1 HETATM 5666 C C5 . NAG B 2 . ? 39.848 194.646 1.602 1.00 61.38 ? 701 NAG A C5 1 HETATM 5667 C C6 . NAG B 2 . ? 40.575 193.714 2.550 1.00 62.42 ? 701 NAG A C6 1 HETATM 5668 C C7 . NAG B 2 . ? 37.794 199.422 0.307 1.00 55.32 ? 701 NAG A C7 1 HETATM 5669 C C8 . NAG B 2 . ? 36.910 200.148 -0.661 1.00 51.42 ? 701 NAG A C8 1 HETATM 5670 N N2 . NAG B 2 . ? 37.953 198.112 0.088 1.00 56.06 ? 701 NAG A N2 1 HETATM 5671 O O3 . NAG B 2 . ? 40.752 197.715 -0.378 1.00 66.32 ? 701 NAG A O3 1 HETATM 5672 O O4 . NAG B 2 . ? 41.743 195.075 0.177 1.00 71.39 ? 701 NAG A O4 1 HETATM 5673 O O5 . NAG B 2 . ? 38.807 195.284 2.357 1.00 63.36 ? 701 NAG A O5 1 HETATM 5674 O O6 . NAG B 2 . ? 40.352 194.049 3.913 1.00 66.31 ? 701 NAG A O6 1 HETATM 5675 O O7 . NAG B 2 . ? 38.338 199.995 1.246 1.00 53.40 ? 701 NAG A O7 1 HETATM 5676 H H1 . NAG B 2 . ? 37.523 195.615 0.863 1.00 68.84 ? 701 NAG A H1 1 HETATM 5677 H H2 . NAG B 2 . ? 39.159 197.804 1.645 1.00 70.82 ? 701 NAG A H2 1 HETATM 5678 H H3 . NAG B 2 . ? 39.559 196.170 -0.633 1.00 77.91 ? 701 NAG A H3 1 HETATM 5679 H H4 . NAG B 2 . ? 41.191 196.214 1.690 1.00 78.00 ? 701 NAG A H4 1 HETATM 5680 H H5 . NAG B 2 . ? 39.443 194.118 0.887 1.00 73.65 ? 701 NAG A H5 1 HETATM 5681 H H61 . NAG B 2 . ? 40.267 192.801 2.394 1.00 74.90 ? 701 NAG A H61 1 HETATM 5682 H H62 . NAG B 2 . ? 41.533 193.760 2.366 1.00 74.90 ? 701 NAG A H62 1 HETATM 5683 H H81 . NAG B 2 . ? 36.015 199.759 -0.639 1.00 61.71 ? 701 NAG A H81 1 HETATM 5684 H H82 . NAG B 2 . ? 36.861 201.091 -0.414 1.00 61.71 ? 701 NAG A H82 1 HETATM 5685 H H83 . NAG B 2 . ? 37.278 200.066 -1.562 1.00 61.71 ? 701 NAG A H83 1 HETATM 5686 H HN2 . NAG B 2 . ? 37.526 197.736 -0.625 1.00 67.27 ? 701 NAG A HN2 1 HETATM 5687 H HO3 . NAG B 2 . ? 41.036 197.506 -1.194 1.00 79.58 ? 701 NAG A HO3 1 HETATM 5688 H HO4 . NAG B 2 . ? 42.535 195.441 0.340 1.00 85.67 ? 701 NAG A HO4 1 HETATM 5689 H HO6 . NAG B 2 . ? 40.629 193.383 4.431 1.00 79.58 ? 701 NAG A HO6 1 HETATM 5690 C C1 . NAG C 2 . ? 5.124 207.013 36.638 1.00 51.60 ? 702 NAG A C1 1 HETATM 5691 C C2 . NAG C 2 . ? 4.714 208.223 37.487 1.00 55.32 ? 702 NAG A C2 1 HETATM 5692 C C3 . NAG C 2 . ? 4.460 207.785 38.924 1.00 54.31 ? 702 NAG A C3 1 HETATM 5693 C C4 . NAG C 2 . ? 3.399 206.691 38.946 1.00 54.95 ? 702 NAG A C4 1 HETATM 5694 C C5 . NAG C 2 . ? 3.772 205.540 38.006 1.00 53.05 ? 702 NAG A C5 1 HETATM 5695 C C6 . NAG C 2 . ? 2.656 204.527 37.868 1.00 58.49 ? 702 NAG A C6 1 HETATM 5696 C C7 . NAG C 2 . ? 5.561 210.387 36.693 1.00 56.89 ? 702 NAG A C7 1 HETATM 5697 C C8 . NAG C 2 . ? 6.670 211.391 36.782 1.00 56.87 ? 702 NAG A C8 1 HETATM 5698 N N2 . NAG C 2 . ? 5.704 209.288 37.442 1.00 52.88 ? 702 NAG A N2 1 HETATM 5699 O O3 . NAG C 2 . ? 4.058 208.898 39.719 1.00 53.54 ? 702 NAG A O3 1 HETATM 5700 O O4 . NAG C 2 . ? 3.267 206.189 40.273 1.00 61.13 ? 702 NAG A O4 1 HETATM 5701 O O5 . NAG C 2 . ? 4.072 206.018 36.679 1.00 48.39 ? 702 NAG A O5 1 HETATM 5702 O O6 . NAG C 2 . ? 2.639 203.633 38.973 1.00 68.94 ? 702 NAG A O6 1 HETATM 5703 O O7 . NAG C 2 . ? 4.583 210.560 35.970 1.00 61.71 ? 702 NAG A O7 1 HETATM 5704 H H1 . NAG C 2 . ? 5.945 206.629 37.000 1.00 61.92 ? 702 NAG A H1 1 HETATM 5705 H H2 . NAG C 2 . ? 3.875 208.570 37.129 1.00 66.38 ? 702 NAG A H2 1 HETATM 5706 H H3 . NAG C 2 . ? 5.288 207.423 39.291 1.00 65.17 ? 702 NAG A H3 1 HETATM 5707 H H4 . NAG C 2 . ? 2.545 207.070 38.663 1.00 65.94 ? 702 NAG A H4 1 HETATM 5708 H H5 . NAG C 2 . ? 4.561 205.089 38.362 1.00 63.66 ? 702 NAG A H5 1 HETATM 5709 H H61 . NAG C 2 . ? 2.786 204.018 37.046 1.00 70.19 ? 702 NAG A H61 1 HETATM 5710 H H62 . NAG C 2 . ? 1.802 204.997 37.823 1.00 70.19 ? 702 NAG A H62 1 HETATM 5711 H H81 . NAG C 2 . ? 6.756 211.700 37.704 1.00 68.25 ? 702 NAG A H81 1 HETATM 5712 H H82 . NAG C 2 . ? 7.507 210.977 36.498 1.00 68.25 ? 702 NAG A H82 1 HETATM 5713 H H83 . NAG C 2 . ? 6.470 212.150 36.202 1.00 68.25 ? 702 NAG A H83 1 HETATM 5714 H HN2 . NAG C 2 . ? 6.447 209.212 37.965 1.00 63.46 ? 702 NAG A HN2 1 HETATM 5715 H HO3 . NAG C 2 . ? 4.253 208.740 40.571 1.00 64.24 ? 702 NAG A HO3 1 HETATM 5716 H HO4 . NAG C 2 . ? 2.524 206.510 40.639 1.00 73.35 ? 702 NAG A HO4 1 HETATM 5717 H HO6 . NAG C 2 . ? 2.317 202.848 38.713 1.00 82.73 ? 702 NAG A HO6 1 HETATM 5718 C C1 . NAG D 2 . ? 30.815 187.293 23.630 1.00 70.42 ? 703 NAG A C1 1 HETATM 5719 C C2 . NAG D 2 . ? 31.385 186.940 25.008 1.00 72.38 ? 703 NAG A C2 1 HETATM 5720 C C3 . NAG D 2 . ? 32.320 185.734 24.906 1.00 75.26 ? 703 NAG A C3 1 HETATM 5721 C C4 . NAG D 2 . ? 31.610 184.565 24.236 1.00 75.46 ? 703 NAG A C4 1 HETATM 5722 C C5 . NAG D 2 . ? 31.053 184.992 22.881 1.00 71.00 ? 703 NAG A C5 1 HETATM 5723 C C6 . NAG D 2 . ? 30.228 183.915 22.216 1.00 68.44 ? 703 NAG A C6 1 HETATM 5724 C C7 . NAG D 2 . ? 31.533 188.886 26.496 1.00 69.37 ? 703 NAG A C7 1 HETATM 5725 C C8 . NAG D 2 . ? 32.397 190.014 26.980 1.00 66.32 ? 703 NAG A C8 1 HETATM 5726 N N2 . NAG D 2 . ? 32.082 188.078 25.585 1.00 72.33 ? 703 NAG A N2 1 HETATM 5727 O O3 . NAG D 2 . ? 32.750 185.358 26.209 1.00 71.90 ? 703 NAG A O3 1 HETATM 5728 O O4 . NAG D 2 . ? 32.514 183.477 24.067 1.00 76.30 ? 703 NAG A O4 1 HETATM 5729 O O5 . NAG D 2 . ? 30.185 186.125 23.048 1.00 74.99 ? 703 NAG A O5 1 HETATM 5730 O O6 . NAG D 2 . ? 29.933 184.246 20.866 1.00 77.63 ? 703 NAG A O6 1 HETATM 5731 O O7 . NAG D 2 . ? 30.392 188.714 26.914 1.00 64.90 ? 703 NAG A O7 1 HETATM 5732 H H1 . NAG D 2 . ? 31.540 187.592 23.049 1.00 84.51 ? 703 NAG A H1 1 HETATM 5733 H H2 . NAG D 2 . ? 30.643 186.699 25.594 1.00 86.86 ? 703 NAG A H2 1 HETATM 5734 H H3 . NAG D 2 . ? 33.099 185.981 24.372 1.00 90.32 ? 703 NAG A H3 1 HETATM 5735 H H4 . NAG D 2 . ? 30.871 184.276 24.805 1.00 90.55 ? 703 NAG A H4 1 HETATM 5736 H H5 . NAG D 2 . ? 31.792 185.239 22.294 1.00 85.20 ? 703 NAG A H5 1 HETATM 5737 H H61 . NAG D 2 . ? 30.724 183.075 22.237 1.00 82.13 ? 703 NAG A H61 1 HETATM 5738 H H62 . NAG D 2 . ? 29.392 183.804 22.707 1.00 82.13 ? 703 NAG A H62 1 HETATM 5739 H H81 . NAG D 2 . ? 33.205 189.652 27.390 1.00 79.58 ? 703 NAG A H81 1 HETATM 5740 H H82 . NAG D 2 . ? 31.906 190.541 27.639 1.00 79.58 ? 703 NAG A H82 1 HETATM 5741 H H83 . NAG D 2 . ? 32.642 190.583 26.226 1.00 79.58 ? 703 NAG A H83 1 HETATM 5742 H HN2 . NAG D 2 . ? 32.934 188.251 25.308 1.00 86.79 ? 703 NAG A HN2 1 HETATM 5743 H HO3 . NAG D 2 . ? 33.617 185.167 26.191 1.00 86.28 ? 703 NAG A HO3 1 HETATM 5744 H HO4 . NAG D 2 . ? 32.319 182.836 24.651 1.00 91.56 ? 703 NAG A HO4 1 HETATM 5745 H HO6 . NAG D 2 . ? 29.605 183.533 20.451 1.00 93.16 ? 703 NAG A HO6 1 HETATM 5746 C C1 . NAG E 2 . ? 24.960 214.139 -13.639 1.00 60.41 ? 704 NAG A C1 1 HETATM 5747 C C2 . NAG E 2 . ? 26.463 214.434 -13.724 1.00 65.95 ? 704 NAG A C2 1 HETATM 5748 C C3 . NAG E 2 . ? 26.794 215.168 -15.024 1.00 73.11 ? 704 NAG A C3 1 HETATM 5749 C C4 . NAG E 2 . ? 26.241 214.413 -16.227 1.00 75.38 ? 704 NAG A C4 1 HETATM 5750 C C5 . NAG E 2 . ? 24.752 214.125 -16.035 1.00 68.97 ? 704 NAG A C5 1 HETATM 5751 C C6 . NAG E 2 . ? 24.160 213.302 -17.155 1.00 65.14 ? 704 NAG A C6 1 HETATM 5752 C C7 . NAG E 2 . ? 27.391 214.645 -11.461 1.00 63.40 ? 704 NAG A C7 1 HETATM 5753 C C8 . NAG E 2 . ? 27.816 215.591 -10.383 1.00 59.65 ? 704 NAG A C8 1 HETATM 5754 N N2 . NAG E 2 . ? 26.913 215.207 -12.576 1.00 65.35 ? 704 NAG A N2 1 HETATM 5755 O O3 . NAG E 2 . ? 28.208 215.291 -15.138 1.00 74.88 ? 704 NAG A O3 1 HETATM 5756 O O4 . NAG E 2 . ? 26.426 215.187 -17.410 1.00 77.16 ? 704 NAG A O4 1 HETATM 5757 O O5 . NAG E 2 . ? 24.542 213.397 -14.811 1.00 57.46 ? 704 NAG A O5 1 HETATM 5758 O O6 . NAG E 2 . ? 24.937 212.142 -17.414 1.00 69.70 ? 704 NAG A O6 1 HETATM 5759 O O7 . NAG E 2 . ? 27.476 213.429 -11.330 1.00 58.05 ? 704 NAG A O7 1 HETATM 5760 H H1 . NAG E 2 . ? 24.468 214.981 -13.599 1.00 72.49 ? 704 NAG A H1 1 HETATM 5761 H H2 . NAG E 2 . ? 26.941 213.583 -13.730 1.00 79.14 ? 704 NAG A H2 1 HETATM 5762 H H3 . NAG E 2 . ? 26.397 216.059 -14.996 1.00 87.73 ? 704 NAG A H3 1 HETATM 5763 H H4 . NAG E 2 . ? 26.720 213.568 -16.321 1.00 90.45 ? 704 NAG A H4 1 HETATM 5764 H H5 . NAG E 2 . ? 24.274 214.974 -15.982 1.00 82.77 ? 704 NAG A H5 1 HETATM 5765 H H61 . NAG E 2 . ? 23.255 213.031 -16.907 1.00 78.17 ? 704 NAG A H61 1 HETATM 5766 H H62 . NAG E 2 . ? 24.120 213.846 -17.964 1.00 78.17 ? 704 NAG A H62 1 HETATM 5767 H H81 . NAG E 2 . ? 28.148 215.084 -9.618 1.00 71.58 ? 704 NAG A H81 1 HETATM 5768 H H82 . NAG E 2 . ? 27.054 216.134 -10.108 1.00 71.58 ? 704 NAG A H82 1 HETATM 5769 H H83 . NAG E 2 . ? 28.525 216.171 -10.721 1.00 71.58 ? 704 NAG A H83 1 HETATM 5770 H HN2 . NAG E 2 . ? 26.875 216.117 -12.622 1.00 78.42 ? 704 NAG A HN2 1 HETATM 5771 H HO3 . NAG E 2 . ? 28.420 216.139 -15.296 1.00 89.86 ? 704 NAG A HO3 1 HETATM 5772 H HO4 . NAG E 2 . ? 27.154 214.909 -17.835 1.00 92.60 ? 704 NAG A HO4 1 HETATM 5773 H HO6 . NAG E 2 . ? 24.551 211.665 -18.057 1.00 83.64 ? 704 NAG A HO6 1 HETATM 5774 O O . HOH F 3 . ? 27.496 220.306 -7.388 1.00 35.35 ? 801 HOH A O 1 HETATM 5775 O O . HOH F 3 . ? 5.430 209.214 41.059 1.00 53.80 ? 802 HOH A O 1 HETATM 5776 O O . HOH F 3 . ? 24.952 195.484 27.771 1.00 36.42 ? 803 HOH A O 1 HETATM 5777 O O . HOH F 3 . ? 20.435 194.261 -1.955 1.00 26.82 ? 804 HOH A O 1 HETATM 5778 O O . HOH F 3 . ? 12.214 187.179 43.092 1.00 32.67 ? 805 HOH A O 1 HETATM 5779 O O . HOH F 3 . ? 2.452 188.363 47.819 1.00 41.48 ? 806 HOH A O 1 HETATM 5780 O O . HOH F 3 . ? 2.881 207.435 42.004 1.00 50.65 ? 807 HOH A O 1 HETATM 5781 O O . HOH F 3 . ? 14.362 206.608 35.324 1.00 31.85 ? 808 HOH A O 1 HETATM 5782 O O . HOH F 3 . ? 12.720 229.706 -16.154 1.00 35.11 ? 809 HOH A O 1 HETATM 5783 O O . HOH F 3 . ? 14.946 206.986 32.503 1.00 30.03 ? 810 HOH A O 1 HETATM 5784 O O . HOH F 3 . ? 22.373 195.132 -4.148 1.00 21.80 ? 811 HOH A O 1 HETATM 5785 O O . HOH F 3 . ? -7.738 203.021 34.679 1.00 27.38 ? 812 HOH A O 1 HETATM 5786 O O . HOH F 3 . ? 27.765 192.396 14.233 1.00 35.79 ? 813 HOH A O 1 HETATM 5787 O O . HOH F 3 . ? 41.596 199.625 -1.500 1.00 55.31 ? 814 HOH A O 1 HETATM 5788 O O . HOH F 3 . ? 15.804 223.816 -12.121 1.00 48.47 ? 815 HOH A O 1 HETATM 5789 O O . HOH F 3 . ? 23.943 251.079 -17.823 1.00 15.81 ? 816 HOH A O 1 HETATM 5790 O O . HOH F 3 . ? 30.634 206.388 -2.935 1.00 32.84 ? 817 HOH A O 1 HETATM 5791 O O . HOH F 3 . ? 17.750 237.240 -18.873 1.00 31.51 ? 818 HOH A O 1 HETATM 5792 O O . HOH F 3 . ? 29.755 187.505 7.370 1.00 47.36 ? 819 HOH A O 1 HETATM 5793 O O . HOH F 3 . ? 28.632 195.851 49.744 1.00 52.69 ? 820 HOH A O 1 HETATM 5794 O O . HOH F 3 . ? 19.338 191.339 4.327 1.00 19.71 ? 821 HOH A O 1 HETATM 5795 O O . HOH F 3 . ? 17.547 184.363 8.125 1.00 34.01 ? 822 HOH A O 1 HETATM 5796 O O . HOH F 3 . ? 30.512 200.036 12.559 1.00 56.36 ? 823 HOH A O 1 HETATM 5797 O O . HOH F 3 . ? 8.333 207.317 3.982 1.00 19.69 ? 824 HOH A O 1 HETATM 5798 O O . HOH F 3 . ? 16.471 204.902 48.623 1.00 29.64 ? 825 HOH A O 1 HETATM 5799 O O . HOH F 3 . ? 23.393 211.728 9.802 1.00 33.06 ? 826 HOH A O 1 HETATM 5800 O O . HOH F 3 . ? 14.430 205.749 -12.916 1.00 35.74 ? 827 HOH A O 1 HETATM 5801 O O . HOH F 3 . ? 2.851 196.951 30.653 1.00 19.25 ? 828 HOH A O 1 HETATM 5802 O O . HOH F 3 . ? 14.429 227.428 -0.649 1.00 28.83 ? 829 HOH A O 1 HETATM 5803 O O . HOH F 3 . ? 27.152 203.695 11.887 1.00 30.47 ? 830 HOH A O 1 HETATM 5804 O O . HOH F 3 . ? 14.616 201.932 16.600 1.00 10.51 ? 831 HOH A O 1 HETATM 5805 O O . HOH F 3 . ? 26.162 203.219 4.791 1.00 17.09 ? 832 HOH A O 1 HETATM 5806 O O . HOH F 3 . ? 24.943 191.215 22.769 1.00 26.29 ? 833 HOH A O 1 HETATM 5807 O O . HOH F 3 . ? 7.202 239.989 -16.043 1.00 31.61 ? 834 HOH A O 1 HETATM 5808 O O . HOH F 3 . ? 27.147 200.401 -2.750 1.00 23.35 ? 835 HOH A O 1 HETATM 5809 O O . HOH F 3 . ? 21.938 208.029 22.388 1.00 21.90 ? 836 HOH A O 1 HETATM 5810 O O . HOH F 3 . ? 24.872 201.205 30.844 1.00 39.00 ? 837 HOH A O 1 HETATM 5811 O O . HOH F 3 . ? 8.395 190.129 11.272 1.00 21.03 ? 838 HOH A O 1 HETATM 5812 O O . HOH F 3 . ? 29.727 193.482 11.572 1.00 37.96 ? 839 HOH A O 1 HETATM 5813 O O . HOH F 3 . ? 6.734 198.436 39.905 1.00 24.66 ? 840 HOH A O 1 HETATM 5814 O O . HOH F 3 . ? 15.394 228.957 -6.985 1.00 20.94 ? 841 HOH A O 1 HETATM 5815 O O . HOH F 3 . ? 9.860 190.973 35.189 1.00 26.39 ? 842 HOH A O 1 HETATM 5816 O O . HOH F 3 . ? 26.883 205.696 8.732 1.00 20.97 ? 843 HOH A O 1 HETATM 5817 O O . HOH F 3 . ? 14.311 206.555 27.604 1.00 23.24 ? 844 HOH A O 1 HETATM 5818 O O . HOH F 3 . ? 34.055 198.442 8.287 1.00 36.72 ? 845 HOH A O 1 HETATM 5819 O O . HOH F 3 . ? 16.365 226.505 -13.260 1.00 28.75 ? 846 HOH A O 1 HETATM 5820 O O . HOH F 3 . ? 8.878 205.085 19.946 1.00 34.78 ? 847 HOH A O 1 HETATM 5821 O O . HOH F 3 . ? 9.505 202.801 39.332 1.00 21.23 ? 848 HOH A O 1 HETATM 5822 O O . HOH F 3 . ? 15.998 185.005 15.980 1.00 20.98 ? 849 HOH A O 1 HETATM 5823 O O . HOH F 3 . ? 6.977 197.658 19.921 1.00 14.39 ? 850 HOH A O 1 HETATM 5824 O O . HOH F 3 . ? 21.321 186.761 34.689 1.00 49.92 ? 851 HOH A O 1 HETATM 5825 O O . HOH F 3 . ? 13.560 185.715 35.748 1.00 28.06 ? 852 HOH A O 1 HETATM 5826 O O . HOH F 3 . ? 5.435 207.390 1.494 1.00 15.43 ? 853 HOH A O 1 HETATM 5827 O O . HOH F 3 . ? 4.852 200.999 14.278 1.00 19.96 ? 854 HOH A O 1 HETATM 5828 O O . HOH F 3 . ? 10.264 189.026 7.806 1.00 28.76 ? 855 HOH A O 1 HETATM 5829 O O . HOH F 3 . ? 10.255 206.575 10.513 1.00 18.34 ? 856 HOH A O 1 HETATM 5830 O O . HOH F 3 . ? 14.419 205.532 22.487 1.00 22.39 ? 857 HOH A O 1 HETATM 5831 O O . HOH F 3 . ? -4.025 195.728 37.710 1.00 29.17 ? 858 HOH A O 1 HETATM 5832 O O . HOH F 3 . ? 11.918 214.419 -14.684 1.00 31.02 ? 859 HOH A O 1 HETATM 5833 O O . HOH F 3 . ? 11.600 193.852 24.555 1.00 18.83 ? 860 HOH A O 1 HETATM 5834 O O . HOH F 3 . ? 30.668 202.460 -6.267 1.00 38.35 ? 861 HOH A O 1 HETATM 5835 O O . HOH F 3 . ? 8.871 200.396 -1.403 1.00 22.29 ? 862 HOH A O 1 HETATM 5836 O O . HOH F 3 . ? 10.811 201.136 -9.723 1.00 26.32 ? 863 HOH A O 1 HETATM 5837 O O . HOH F 3 . ? 20.592 207.299 37.241 1.00 40.46 ? 864 HOH A O 1 HETATM 5838 O O . HOH F 3 . ? 8.507 189.320 42.149 1.00 30.04 ? 865 HOH A O 1 HETATM 5839 O O . HOH F 3 . ? 6.825 190.695 7.506 1.00 22.26 ? 866 HOH A O 1 HETATM 5840 O O . HOH F 3 . ? 7.563 198.103 36.720 1.00 27.58 ? 867 HOH A O 1 HETATM 5841 O O . HOH F 3 . ? 17.048 191.141 47.893 1.00 13.68 ? 868 HOH A O 1 HETATM 5842 O O . HOH F 3 . ? 4.838 201.503 6.433 1.00 19.70 ? 869 HOH A O 1 HETATM 5843 O O . HOH F 3 . ? 11.799 200.200 -3.601 1.00 25.79 ? 870 HOH A O 1 HETATM 5844 O O . HOH F 3 . ? 10.442 194.199 55.021 1.00 37.78 ? 871 HOH A O 1 HETATM 5845 O O . HOH F 3 . ? 13.078 211.996 14.119 1.00 40.05 ? 872 HOH A O 1 HETATM 5846 O O . HOH F 3 . ? 16.687 223.623 -0.344 1.00 28.52 ? 873 HOH A O 1 HETATM 5847 O O . HOH F 3 . ? 8.591 227.281 -6.284 1.00 46.60 ? 874 HOH A O 1 HETATM 5848 O O . HOH F 3 . ? 5.050 175.498 48.141 1.00 21.76 ? 875 HOH A O 1 HETATM 5849 O O . HOH F 3 . ? 11.700 197.631 -4.188 1.00 29.33 ? 876 HOH A O 1 HETATM 5850 O O . HOH F 3 . ? 14.174 209.363 16.801 1.00 29.06 ? 877 HOH A O 1 HETATM 5851 O O . HOH F 3 . ? 9.554 199.060 38.654 1.00 25.43 ? 878 HOH A O 1 HETATM 5852 O O . HOH F 3 . ? 14.790 186.634 31.760 1.00 28.28 ? 879 HOH A O 1 HETATM 5853 O O . HOH F 3 . ? 14.740 184.528 45.380 1.00 24.74 ? 880 HOH A O 1 HETATM 5854 O O . HOH F 3 . ? 4.063 203.140 25.611 1.00 26.06 ? 881 HOH A O 1 HETATM 5855 O O . HOH F 3 . ? 16.423 186.667 12.728 1.00 23.32 ? 882 HOH A O 1 HETATM 5856 O O . HOH F 3 . ? 2.289 190.860 35.647 1.00 25.92 ? 883 HOH A O 1 HETATM 5857 O O . HOH F 3 . ? 9.687 198.919 0.777 1.00 21.21 ? 884 HOH A O 1 HETATM 5858 O O . HOH F 3 . ? 24.980 223.476 1.161 1.00 43.96 ? 885 HOH A O 1 HETATM 5859 O O . HOH F 3 . ? 43.164 192.951 -0.784 1.00 49.61 ? 886 HOH A O 1 HETATM 5860 O O . HOH F 3 . ? 11.814 184.218 42.187 1.00 26.83 ? 887 HOH A O 1 HETATM 5861 O O . HOH F 3 . ? 13.858 193.531 41.403 1.00 24.00 ? 888 HOH A O 1 HETATM 5862 O O . HOH F 3 . ? 10.232 205.167 13.178 1.00 12.43 ? 889 HOH A O 1 HETATM 5863 O O . HOH F 3 . ? 20.472 183.558 8.862 1.00 38.04 ? 890 HOH A O 1 HETATM 5864 O O . HOH F 3 . ? 9.551 206.975 6.648 1.00 19.03 ? 891 HOH A O 1 HETATM 5865 O O . HOH F 3 . ? 2.356 241.218 -6.388 1.00 46.29 ? 892 HOH A O 1 HETATM 5866 O O . HOH F 3 . ? 11.587 221.393 -9.859 1.00 28.00 ? 893 HOH A O 1 HETATM 5867 O O . HOH F 3 . ? 23.155 190.679 -1.710 1.00 22.08 ? 894 HOH A O 1 HETATM 5868 O O . HOH F 3 . ? 26.023 216.752 1.946 1.00 45.37 ? 895 HOH A O 1 HETATM 5869 O O . HOH F 3 . ? 3.299 192.592 26.123 1.00 30.93 ? 896 HOH A O 1 HETATM 5870 O O . HOH F 3 . ? 12.100 227.839 -3.477 1.00 36.69 ? 897 HOH A O 1 HETATM 5871 O O . HOH F 3 . ? 7.547 240.434 -6.266 1.00 37.73 ? 898 HOH A O 1 HETATM 5872 O O . HOH F 3 . ? 27.433 212.669 2.339 1.00 32.20 ? 899 HOH A O 1 HETATM 5873 O O . HOH F 3 . ? 3.558 191.013 38.462 1.00 30.14 ? 900 HOH A O 1 HETATM 5874 O O . HOH F 3 . ? 19.413 233.363 -2.421 1.00 36.42 ? 901 HOH A O 1 HETATM 5875 O O . HOH F 3 . ? 7.419 182.295 52.905 1.00 18.69 ? 902 HOH A O 1 HETATM 5876 O O . HOH F 3 . ? 23.700 252.498 -7.416 1.00 32.60 ? 903 HOH A O 1 HETATM 5877 O O . HOH F 3 . ? 2.656 193.297 36.300 1.00 24.73 ? 904 HOH A O 1 HETATM 5878 O O . HOH F 3 . ? 20.937 191.626 26.133 1.00 32.44 ? 905 HOH A O 1 HETATM 5879 O O . HOH F 3 . ? 7.414 204.250 34.380 1.00 36.96 ? 906 HOH A O 1 HETATM 5880 O O . HOH F 3 . ? 14.844 184.887 20.919 1.00 34.91 ? 907 HOH A O 1 HETATM 5881 O O . HOH F 3 . ? 25.170 208.805 9.701 1.00 39.08 ? 908 HOH A O 1 HETATM 5882 O O . HOH F 3 . ? 2.689 197.572 0.633 1.00 22.38 ? 909 HOH A O 1 HETATM 5883 O O . HOH F 3 . ? 35.761 195.002 -1.629 1.00 38.23 ? 910 HOH A O 1 HETATM 5884 O O . HOH F 3 . ? 31.596 206.216 1.544 1.00 47.88 ? 911 HOH A O 1 HETATM 5885 O O . HOH F 3 . ? 17.929 207.778 20.927 1.00 24.56 ? 912 HOH A O 1 HETATM 5886 O O . HOH F 3 . ? 24.618 186.626 12.339 1.00 28.43 ? 913 HOH A O 1 HETATM 5887 O O . HOH F 3 . ? 6.748 201.262 41.304 1.00 29.84 ? 914 HOH A O 1 HETATM 5888 O O . HOH F 3 . ? 24.667 225.016 -8.111 1.00 25.75 ? 915 HOH A O 1 HETATM 5889 O O . HOH F 3 . ? 5.108 196.540 49.985 1.00 41.37 ? 916 HOH A O 1 HETATM 5890 O O . HOH F 3 . ? 25.282 212.009 -20.220 1.00 54.57 ? 917 HOH A O 1 HETATM 5891 O O . HOH F 3 . ? 7.610 195.602 9.818 1.00 15.13 ? 918 HOH A O 1 HETATM 5892 O O . HOH F 3 . ? 6.761 214.321 1.321 1.00 28.77 ? 919 HOH A O 1 HETATM 5893 O O . HOH F 3 . ? 22.120 196.257 41.007 1.00 20.25 ? 920 HOH A O 1 HETATM 5894 O O . HOH F 3 . ? 3.129 194.459 29.715 1.00 23.39 ? 921 HOH A O 1 HETATM 5895 O O . HOH F 3 . ? 6.460 218.067 0.522 1.00 47.21 ? 922 HOH A O 1 HETATM 5896 O O . HOH F 3 . ? 20.785 205.126 24.740 1.00 47.64 ? 923 HOH A O 1 HETATM 5897 O O . HOH F 3 . ? 4.098 188.011 21.336 1.00 39.53 ? 924 HOH A O 1 HETATM 5898 O O . HOH F 3 . ? 17.975 185.788 19.601 1.00 34.40 ? 925 HOH A O 1 HETATM 5899 O O . HOH F 3 . ? 24.620 184.804 4.928 1.00 50.79 ? 926 HOH A O 1 HETATM 5900 O O . HOH F 3 . ? 10.116 197.177 46.645 1.00 16.17 ? 927 HOH A O 1 HETATM 5901 O O . HOH F 3 . ? 5.688 203.989 33.799 1.00 36.59 ? 928 HOH A O 1 HETATM 5902 O O . HOH F 3 . ? 8.460 243.650 -6.114 1.00 40.57 ? 929 HOH A O 1 HETATM 5903 O O . HOH F 3 . ? 13.513 183.691 48.580 1.00 15.74 ? 930 HOH A O 1 HETATM 5904 O O . HOH F 3 . ? 10.568 195.784 -2.964 1.00 30.80 ? 931 HOH A O 1 HETATM 5905 O O . HOH F 3 . ? 24.574 199.904 22.632 1.00 13.42 ? 932 HOH A O 1 HETATM 5906 O O . HOH F 3 . ? 23.395 247.307 -19.194 1.00 22.62 ? 933 HOH A O 1 HETATM 5907 O O . HOH F 3 . ? 9.541 226.356 -8.905 1.00 35.85 ? 934 HOH A O 1 HETATM 5908 O O . HOH F 3 . ? 1.950 205.869 -5.006 1.00 33.58 ? 935 HOH A O 1 HETATM 5909 O O . HOH F 3 . ? 12.965 225.524 -6.781 1.00 26.91 ? 936 HOH A O 1 HETATM 5910 O O . HOH F 3 . ? 6.112 195.824 23.451 1.00 21.77 ? 937 HOH A O 1 HETATM 5911 O O . HOH F 3 . ? 10.496 206.066 27.832 1.00 21.88 ? 938 HOH A O 1 HETATM 5912 O O . HOH F 3 . ? 20.711 203.069 39.372 1.00 38.64 ? 939 HOH A O 1 HETATM 5913 O O . HOH F 3 . ? -1.268 200.053 31.695 1.00 31.94 ? 940 HOH A O 1 HETATM 5914 O O . HOH F 3 . ? 3.383 207.597 13.466 1.00 32.65 ? 941 HOH A O 1 HETATM 5915 O O . HOH F 3 . ? 12.878 187.947 25.320 1.00 19.20 ? 942 HOH A O 1 HETATM 5916 O O . HOH F 3 . ? 9.816 219.137 -12.160 1.00 39.74 ? 943 HOH A O 1 HETATM 5917 O O . HOH F 3 . ? 21.152 204.444 37.227 1.00 34.65 ? 944 HOH A O 1 HETATM 5918 O O . HOH F 3 . ? 19.055 228.096 -13.376 1.00 25.67 ? 945 HOH A O 1 HETATM 5919 O O . HOH F 3 . ? 12.325 205.876 25.860 1.00 23.38 ? 946 HOH A O 1 HETATM 5920 O O . HOH F 3 . ? 26.721 187.106 11.119 1.00 45.38 ? 947 HOH A O 1 HETATM 5921 O O . HOH F 3 . ? 1.689 198.105 28.241 1.00 25.65 ? 948 HOH A O 1 HETATM 5922 O O . HOH F 3 . ? 28.042 196.986 16.983 1.00 26.04 ? 949 HOH A O 1 HETATM 5923 O O . HOH F 3 . ? 19.024 195.636 -0.060 1.00 14.90 ? 950 HOH A O 1 HETATM 5924 O O . HOH F 3 . ? 8.939 202.635 20.865 1.00 16.14 ? 951 HOH A O 1 HETATM 5925 O O . HOH F 3 . ? 19.611 189.753 39.579 1.00 32.99 ? 952 HOH A O 1 HETATM 5926 O O . HOH F 3 . ? 21.504 215.881 8.810 1.00 19.24 ? 953 HOH A O 1 HETATM 5927 O O . HOH F 3 . ? 22.991 244.233 -16.862 1.00 36.30 ? 954 HOH A O 1 HETATM 5928 O O . HOH F 3 . ? 5.127 183.888 38.106 1.00 24.84 ? 955 HOH A O 1 HETATM 5929 O O . HOH F 3 . ? 5.078 205.094 29.529 1.00 25.71 ? 956 HOH A O 1 HETATM 5930 O O . HOH F 3 . ? 21.076 189.489 37.221 1.00 38.26 ? 957 HOH A O 1 HETATM 5931 O O . HOH F 3 . ? 19.887 244.199 -18.615 1.00 29.45 ? 958 HOH A O 1 HETATM 5932 O O . HOH F 3 . ? 12.227 187.070 15.344 1.00 20.35 ? 959 HOH A O 1 HETATM 5933 O O . HOH F 3 . ? 6.531 198.449 46.681 1.00 40.40 ? 960 HOH A O 1 HETATM 5934 O O . HOH F 3 . ? 14.603 194.398 -3.678 1.00 34.80 ? 961 HOH A O 1 HETATM 5935 O O . HOH F 3 . ? 29.998 209.276 5.283 1.00 44.56 ? 962 HOH A O 1 HETATM 5936 O O . HOH F 3 . ? 19.395 226.154 -6.413 1.00 30.13 ? 963 HOH A O 1 HETATM 5937 O O . HOH F 3 . ? -1.561 195.032 13.493 1.00 30.22 ? 964 HOH A O 1 HETATM 5938 O O . HOH F 3 . ? 8.300 204.290 -8.618 1.00 25.13 ? 965 HOH A O 1 HETATM 5939 O O . HOH F 3 . ? 7.111 201.146 45.353 1.00 40.03 ? 966 HOH A O 1 HETATM 5940 O O . HOH F 3 . ? 33.384 204.262 4.831 1.00 35.90 ? 967 HOH A O 1 HETATM 5941 O O . HOH F 3 . ? 10.336 187.789 57.791 1.00 32.67 ? 968 HOH A O 1 HETATM 5942 O O . HOH F 3 . ? 7.865 204.731 38.453 1.00 46.07 ? 969 HOH A O 1 HETATM 5943 O O . HOH F 3 . ? 5.716 193.636 17.570 1.00 19.84 ? 970 HOH A O 1 HETATM 5944 O O . HOH F 3 . ? 3.549 188.496 54.420 1.00 21.39 ? 971 HOH A O 1 HETATM 5945 O O . HOH F 3 . ? 3.249 194.180 51.304 1.00 30.84 ? 972 HOH A O 1 HETATM 5946 O O . HOH F 3 . ? 15.935 235.588 -20.694 1.00 44.48 ? 973 HOH A O 1 HETATM 5947 O O . HOH F 3 . ? 16.883 226.225 -7.069 1.00 32.05 ? 974 HOH A O 1 HETATM 5948 O O . HOH F 3 . ? 11.704 249.859 -14.649 1.00 54.06 ? 975 HOH A O 1 HETATM 5949 O O . HOH F 3 . ? 27.062 184.927 1.240 1.00 22.02 ? 976 HOH A O 1 HETATM 5950 O O . HOH F 3 . ? 7.033 214.990 3.999 1.00 35.27 ? 977 HOH A O 1 HETATM 5951 O O . HOH F 3 . ? 20.700 209.345 42.905 1.00 29.79 ? 978 HOH A O 1 HETATM 5952 O O . HOH F 3 . ? 32.890 190.886 0.509 1.00 32.09 ? 979 HOH A O 1 HETATM 5953 O O . HOH F 3 . ? 0.000 241.432 -15.790 0.50 17.45 ? 980 HOH A O 1 HETATM 5954 O O . HOH F 3 . ? 27.588 186.431 7.863 1.00 33.41 ? 981 HOH A O 1 HETATM 5955 O O . HOH F 3 . ? 23.284 218.951 2.618 1.00 26.28 ? 982 HOH A O 1 HETATM 5956 O O . HOH F 3 . ? 15.922 199.471 22.489 1.00 23.54 ? 983 HOH A O 1 HETATM 5957 O O . HOH F 3 . ? 25.961 191.509 32.873 1.00 38.70 ? 984 HOH A O 1 HETATM 5958 O O . HOH F 3 . ? 11.630 179.827 58.295 1.00 21.35 ? 985 HOH A O 1 HETATM 5959 O O . HOH F 3 . ? 21.226 207.094 29.865 1.00 27.16 ? 986 HOH A O 1 HETATM 5960 O O . HOH F 3 . ? 15.479 207.362 24.720 1.00 22.42 ? 987 HOH A O 1 HETATM 5961 O O . HOH F 3 . ? 12.205 208.057 19.786 1.00 22.54 ? 988 HOH A O 1 HETATM 5962 O O . HOH F 3 . ? 11.539 244.721 -20.377 1.00 50.89 ? 989 HOH A O 1 HETATM 5963 O O . HOH F 3 . ? 16.789 250.902 -18.715 1.00 14.73 ? 990 HOH A O 1 HETATM 5964 O O . HOH F 3 . ? 28.962 189.839 -5.117 1.00 39.01 ? 991 HOH A O 1 HETATM 5965 O O . HOH F 3 . ? 27.552 194.270 17.599 1.00 42.48 ? 992 HOH A O 1 HETATM 5966 O O . HOH F 3 . ? 24.165 229.108 -0.636 1.00 27.79 ? 993 HOH A O 1 HETATM 5967 O O . HOH F 3 . ? 28.099 183.558 -4.025 1.00 32.28 ? 994 HOH A O 1 HETATM 5968 O O . HOH F 3 . ? 26.286 214.518 -5.510 1.00 28.39 ? 995 HOH A O 1 HETATM 5969 O O . HOH F 3 . ? 29.260 197.320 47.808 1.00 46.98 ? 996 HOH A O 1 HETATM 5970 O O . HOH F 3 . ? 25.012 194.751 49.431 1.00 38.91 ? 997 HOH A O 1 HETATM 5971 O O . HOH F 3 . ? 9.257 196.081 -0.132 1.00 33.89 ? 998 HOH A O 1 HETATM 5972 O O . HOH F 3 . ? 9.416 204.398 46.148 1.00 21.53 ? 999 HOH A O 1 HETATM 5973 O O . HOH F 3 . ? 30.144 198.698 -4.011 1.00 53.89 ? 1000 HOH A O 1 HETATM 5974 O O . HOH F 3 . ? 10.356 208.700 8.869 1.00 25.27 ? 1001 HOH A O 1 HETATM 5975 O O . HOH F 3 . ? 23.347 183.990 0.000 0.50 22.13 ? 1002 HOH A O 1 HETATM 5976 O O . HOH F 3 . ? 6.755 207.582 29.004 1.00 44.43 ? 1003 HOH A O 1 HETATM 5977 O O . HOH F 3 . ? 24.315 213.053 -4.811 1.00 24.75 ? 1004 HOH A O 1 HETATM 5978 O O . HOH F 3 . ? 31.108 191.556 -3.899 1.00 37.76 ? 1005 HOH A O 1 HETATM 5979 O O . HOH F 3 . ? 11.447 224.286 -8.765 1.00 57.06 ? 1006 HOH A O 1 HETATM 5980 O O . HOH F 3 . ? 20.060 183.976 6.958 1.00 37.02 ? 1007 HOH A O 1 HETATM 5981 O O . HOH F 3 . ? 24.246 191.199 -4.473 1.00 56.32 ? 1008 HOH A O 1 HETATM 5982 O O . HOH F 3 . ? 0.198 200.472 3.168 1.00 28.44 ? 1009 HOH A O 1 HETATM 5983 O O . HOH F 3 . ? 23.289 185.258 12.084 1.00 33.26 ? 1010 HOH A O 1 HETATM 5984 O O . HOH F 3 . ? 7.751 180.302 54.879 1.00 21.82 ? 1011 HOH A O 1 HETATM 5985 O O . HOH F 3 . ? 5.319 203.602 41.840 1.00 44.20 ? 1012 HOH A O 1 HETATM 5986 O O . HOH F 3 . ? 0.704 193.468 14.563 1.00 26.91 ? 1013 HOH A O 1 HETATM 5987 O O . HOH F 3 . ? 15.145 184.165 51.038 1.00 30.55 ? 1014 HOH A O 1 HETATM 5988 O O . HOH F 3 . ? 12.609 206.402 -13.965 1.00 45.06 ? 1015 HOH A O 1 HETATM 5989 O O . HOH F 3 . ? 23.691 206.091 31.024 1.00 31.75 ? 1016 HOH A O 1 HETATM 5990 O O . HOH F 3 . ? 17.556 209.346 23.101 1.00 41.00 ? 1017 HOH A O 1 HETATM 5991 O O . HOH F 3 . ? 28.916 211.422 4.097 1.00 33.13 ? 1018 HOH A O 1 HETATM 5992 O O . HOH F 3 . ? 25.305 245.869 -12.478 1.00 39.72 ? 1019 HOH A O 1 HETATM 5993 O O . HOH F 3 . ? 0.902 202.641 14.704 1.00 38.21 ? 1020 HOH A O 1 HETATM 5994 O O . HOH F 3 . ? 17.572 193.379 -0.092 1.00 24.44 ? 1021 HOH A O 1 HETATM 5995 O O . HOH F 3 . ? 17.265 191.560 2.264 1.00 31.93 ? 1022 HOH A O 1 HETATM 5996 O O . HOH F 3 . ? 25.473 244.070 -14.696 1.00 35.53 ? 1023 HOH A O 1 HETATM 5997 O O . HOH F 3 . ? 10.318 197.258 56.851 1.00 46.91 ? 1024 HOH A O 1 HETATM 5998 O O . HOH F 3 . ? 21.167 184.017 1.819 1.00 36.46 ? 1025 HOH A O 1 HETATM 5999 O O . HOH F 3 . ? 14.362 207.724 21.202 1.00 39.23 ? 1026 HOH A O 1 HETATM 6000 O O . HOH F 3 . ? 15.674 211.370 16.728 1.00 39.54 ? 1027 HOH A O 1 HETATM 6001 O O . HOH F 3 . ? 27.119 249.100 -9.601 1.00 60.39 ? 1028 HOH A O 1 HETATM 6002 O O . HOH F 3 . ? 26.422 249.307 -17.938 1.00 29.45 ? 1029 HOH A O 1 HETATM 6003 O O . HOH F 3 . ? 8.683 198.901 48.635 1.00 35.93 ? 1030 HOH A O 1 HETATM 6004 O O . HOH F 3 . ? 11.508 207.187 23.927 1.00 33.34 ? 1031 HOH A O 1 HETATM 6005 O O . HOH F 3 . ? 2.171 200.047 13.847 1.00 25.39 ? 1032 HOH A O 1 HETATM 6006 O O . HOH F 3 . ? 31.972 199.766 -2.215 1.00 44.92 ? 1033 HOH A O 1 HETATM 6007 O O . HOH F 3 . ? 8.794 201.719 48.373 1.00 41.21 ? 1034 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 SER 1 307 ? ? ? A . n A 1 2 GLY 2 308 ? ? ? A . n A 1 3 PHE 3 309 ? ? ? A . n A 1 4 THR 4 310 ? ? ? A . n A 1 5 VAL 5 311 311 VAL VAL A . n A 1 6 LYS 6 312 312 LYS LYS A . n A 1 7 PRO 7 313 313 PRO PRO A . n A 1 8 VAL 8 314 314 VAL VAL A . n A 1 9 ALA 9 315 315 ALA ALA A . n A 1 10 THR 10 316 316 THR THR A . n A 1 11 VAL 11 317 317 VAL VAL A . n A 1 12 HIS 12 318 318 HIS HIS A . n A 1 13 ARG 13 319 319 ARG ARG A . n A 1 14 ARG 14 320 320 ARG ARG A . n A 1 15 ILE 15 321 321 ILE ILE A . n A 1 16 PRO 16 322 322 PRO PRO A . n A 1 17 ASP 17 323 323 ASP ASP A . n A 1 18 LEU 18 324 324 LEU LEU A . n A 1 19 PRO 19 325 325 PRO PRO A . n A 1 20 ASP 20 326 326 ASP ASP A . n A 1 21 CYS 21 327 327 CYS CYS A . n A 1 22 ASP 22 328 328 ASP ASP A . n A 1 23 ILE 23 329 329 ILE ILE A . n A 1 24 ASP 24 330 330 ASP ASP A . n A 1 25 LYS 25 331 331 LYS LYS A . n A 1 26 TRP 26 332 332 TRP TRP A . n A 1 27 LEU 27 333 333 LEU LEU A . n A 1 28 ASN 28 334 334 ASN ASN A . n A 1 29 ASN 29 335 335 ASN ASN A . n A 1 30 PHE 30 336 336 PHE PHE A . n A 1 31 ASN 31 337 337 ASN ASN A . n A 1 32 VAL 32 338 338 VAL VAL A . n A 1 33 PRO 33 339 339 PRO PRO A . n A 1 34 SER 34 340 340 SER SER A . n A 1 35 PRO 35 341 341 PRO PRO A . n A 1 36 LEU 36 342 342 LEU LEU A . n A 1 37 ASN 37 343 343 ASN ASN A . n A 1 38 TRP 38 344 344 TRP TRP A . n A 1 39 GLU 39 345 345 GLU GLU A . n A 1 40 ARG 40 346 346 ARG ARG A . n A 1 41 LYS 41 347 347 LYS LYS A . n A 1 42 ILE 42 348 348 ILE ILE A . n A 1 43 PHE 43 349 349 PHE PHE A . n A 1 44 SER 44 350 350 SER SER A . n A 1 45 ASN 45 351 351 ASN ASN A . n A 1 46 CYS 46 352 352 CYS CYS A . n A 1 47 ASN 47 353 353 ASN ASN A . n A 1 48 PHE 48 354 354 PHE PHE A . n A 1 49 ASN 49 355 355 ASN ASN A . n A 1 50 LEU 50 356 356 LEU LEU A . n A 1 51 SER 51 357 357 SER SER A . n A 1 52 THR 52 358 358 THR THR A . n A 1 53 LEU 53 359 359 LEU LEU A . n A 1 54 LEU 54 360 360 LEU LEU A . n A 1 55 ARG 55 361 361 ARG ARG A . n A 1 56 LEU 56 362 362 LEU LEU A . n A 1 57 VAL 57 363 363 VAL VAL A . n A 1 58 HIS 58 364 364 HIS HIS A . n A 1 59 THR 59 365 365 THR THR A . n A 1 60 ASP 60 366 366 ASP ASP A . n A 1 61 SER 61 367 367 SER SER A . n A 1 62 PHE 62 368 368 PHE PHE A . n A 1 63 SER 63 369 369 SER SER A . n A 1 64 CYS 64 370 370 CYS CYS A . n A 1 65 ASN 65 371 371 ASN ASN A . n A 1 66 ASN 66 372 372 ASN ASN A . n A 1 67 PHE 67 373 373 PHE PHE A . n A 1 68 ASP 68 374 374 ASP ASP A . n A 1 69 GLU 69 375 375 GLU GLU A . n A 1 70 SER 70 376 376 SER SER A . n A 1 71 LYS 71 377 377 LYS LYS A . n A 1 72 ILE 72 378 378 ILE ILE A . n A 1 73 TYR 73 379 379 TYR TYR A . n A 1 74 GLY 74 380 380 GLY GLY A . n A 1 75 SER 75 381 381 SER SER A . n A 1 76 CYS 76 382 382 CYS CYS A . n A 1 77 PHE 77 383 383 PHE PHE A . n A 1 78 LYS 78 384 384 LYS LYS A . n A 1 79 SER 79 385 385 SER SER A . n A 1 80 ILE 80 386 386 ILE ILE A . n A 1 81 VAL 81 387 387 VAL VAL A . n A 1 82 LEU 82 388 388 LEU LEU A . n A 1 83 ASP 83 389 389 ASP ASP A . n A 1 84 LYS 84 390 390 LYS LYS A . n A 1 85 PHE 85 391 391 PHE PHE A . n A 1 86 ALA 86 392 392 ALA ALA A . n A 1 87 ILE 87 393 393 ILE ILE A . n A 1 88 PRO 88 394 394 PRO PRO A . n A 1 89 ASN 89 395 395 ASN ASN A . n A 1 90 SER 90 396 396 SER SER A . n A 1 91 ARG 91 397 397 ARG ARG A . n A 1 92 ARG 92 398 398 ARG ARG A . n A 1 93 SER 93 399 399 SER SER A . n A 1 94 ASP 94 400 400 ASP ASP A . n A 1 95 LEU 95 401 401 LEU LEU A . n A 1 96 GLN 96 402 402 GLN GLN A . n A 1 97 LEU 97 403 403 LEU LEU A . n A 1 98 GLY 98 404 404 GLY GLY A . n A 1 99 SER 99 405 405 SER SER A . n A 1 100 SER 100 406 406 SER SER A . n A 1 101 GLY 101 407 407 GLY GLY A . n A 1 102 PHE 102 408 408 PHE PHE A . n A 1 103 LEU 103 409 409 LEU LEU A . n A 1 104 GLN 104 410 410 GLN GLN A . n A 1 105 SER 105 411 411 SER SER A . n A 1 106 SER 106 412 412 SER SER A . n A 1 107 ASN 107 413 413 ASN ASN A . n A 1 108 TYR 108 414 414 TYR TYR A . n A 1 109 LYS 109 415 415 LYS LYS A . n A 1 110 ILE 110 416 416 ILE ILE A . n A 1 111 ASP 111 417 417 ASP ASP A . n A 1 112 THR 112 418 418 THR THR A . n A 1 113 THR 113 419 419 THR THR A . n A 1 114 SER 114 420 420 SER SER A . n A 1 115 SER 115 421 421 SER SER A . n A 1 116 SER 116 422 422 SER SER A . n A 1 117 CYS 117 423 423 CYS CYS A . n A 1 118 GLN 118 424 424 GLN GLN A . n A 1 119 LEU 119 425 425 LEU LEU A . n A 1 120 TYR 120 426 426 TYR TYR A . n A 1 121 TYR 121 427 427 TYR TYR A . n A 1 122 SER 122 428 428 SER SER A . n A 1 123 LEU 123 429 429 LEU LEU A . n A 1 124 PRO 124 430 430 PRO PRO A . n A 1 125 ALA 125 431 431 ALA ALA A . n A 1 126 ILE 126 432 432 ILE ILE A . n A 1 127 ASN 127 433 433 ASN ASN A . n A 1 128 VAL 128 434 434 VAL VAL A . n A 1 129 THR 129 435 435 THR THR A . n A 1 130 ILE 130 436 436 ILE ILE A . n A 1 131 ASN 131 437 437 ASN ASN A . n A 1 132 ASN 132 438 438 ASN ASN A . n A 1 133 TYR 133 439 439 TYR TYR A . n A 1 134 ASN 134 440 440 ASN ASN A . n A 1 135 PRO 135 441 441 PRO PRO A . n A 1 136 SER 136 442 442 SER SER A . n A 1 137 SER 137 443 443 SER SER A . n A 1 138 TRP 138 444 444 TRP TRP A . n A 1 139 ASN 139 445 445 ASN ASN A . n A 1 140 ARG 140 446 446 ARG ARG A . n A 1 141 ARG 141 447 447 ARG ARG A . n A 1 142 TYR 142 448 448 TYR TYR A . n A 1 143 GLY 143 449 449 GLY GLY A . n A 1 144 PHE 144 450 450 PHE PHE A . n A 1 145 ASN 145 451 451 ASN ASN A . n A 1 146 ASN 146 452 452 ASN ASN A . n A 1 147 PHE 147 453 453 PHE PHE A . n A 1 148 ASN 148 454 454 ASN ASN A . n A 1 149 LEU 149 455 455 LEU LEU A . n A 1 150 SER 150 456 456 SER SER A . n A 1 151 SER 151 457 457 SER SER A . n A 1 152 HIS 152 458 458 HIS HIS A . n A 1 153 SER 153 459 459 SER SER A . n A 1 154 VAL 154 460 460 VAL VAL A . n A 1 155 VAL 155 461 461 VAL VAL A . n A 1 156 TYR 156 462 462 TYR TYR A . n A 1 157 SER 157 463 463 SER SER A . n A 1 158 ARG 158 464 464 ARG ARG A . n A 1 159 TYR 159 465 465 TYR TYR A . n A 1 160 CYS 160 466 466 CYS CYS A . n A 1 161 PHE 161 467 467 PHE PHE A . n A 1 162 SER 162 468 468 SER SER A . n A 1 163 VAL 163 469 469 VAL VAL A . n A 1 164 ASN 164 470 470 ASN ASN A . n A 1 165 ASN 165 471 471 ASN ASN A . n A 1 166 THR 166 472 472 THR THR A . n A 1 167 PHE 167 473 473 PHE PHE A . n A 1 168 CYS 168 474 474 CYS CYS A . n A 1 169 PRO 169 475 475 PRO PRO A . n A 1 170 CYS 170 476 476 CYS CYS A . n A 1 171 ALA 171 477 477 ALA ALA A . n A 1 172 LYS 172 478 478 LYS LYS A . n A 1 173 PRO 173 479 479 PRO PRO A . n A 1 174 SER 174 480 480 SER SER A . n A 1 175 PHE 175 481 481 PHE PHE A . n A 1 176 ALA 176 482 482 ALA ALA A . n A 1 177 SER 177 483 483 SER SER A . n A 1 178 SER 178 484 484 SER SER A . n A 1 179 CYS 179 485 485 CYS CYS A . n A 1 180 LYS 180 486 486 LYS LYS A . n A 1 181 SER 181 487 487 SER SER A . n A 1 182 HIS 182 488 488 HIS HIS A . n A 1 183 LYS 183 489 489 LYS LYS A . n A 1 184 PRO 184 490 490 PRO PRO A . n A 1 185 PRO 185 491 491 PRO PRO A . n A 1 186 SER 186 492 492 SER SER A . n A 1 187 ALA 187 493 493 ALA ALA A . n A 1 188 SER 188 494 494 SER SER A . n A 1 189 CYS 189 495 495 CYS CYS A . n A 1 190 PRO 190 496 496 PRO PRO A . n A 1 191 ILE 191 497 497 ILE ILE A . n A 1 192 GLY 192 498 498 GLY GLY A . n A 1 193 THR 193 499 499 THR THR A . n A 1 194 ASN 194 500 500 ASN ASN A . n A 1 195 TYR 195 501 501 TYR TYR A . n A 1 196 ARG 196 502 502 ARG ARG A . n A 1 197 SER 197 503 503 SER SER A . n A 1 198 CYS 198 504 504 CYS CYS A . n A 1 199 GLU 199 505 505 GLU GLU A . n A 1 200 SER 200 506 506 SER SER A . n A 1 201 THR 201 507 507 THR THR A . n A 1 202 THR 202 508 508 THR THR A . n A 1 203 VAL 203 509 509 VAL VAL A . n A 1 204 LEU 204 510 510 LEU LEU A . n A 1 205 ASP 205 511 511 ASP ASP A . n A 1 206 HIS 206 512 512 HIS HIS A . n A 1 207 THR 207 513 513 THR THR A . n A 1 208 ASP 208 514 514 ASP ASP A . n A 1 209 TRP 209 515 515 TRP TRP A . n A 1 210 CYS 210 516 516 CYS CYS A . n A 1 211 ARG 211 517 517 ARG ARG A . n A 1 212 CYS 212 518 518 CYS CYS A . n A 1 213 SER 213 519 519 SER SER A . n A 1 214 CYS 214 520 520 CYS CYS A . n A 1 215 LEU 215 521 521 LEU LEU A . n A 1 216 PRO 216 522 522 PRO PRO A . n A 1 217 ASP 217 523 523 ASP ASP A . n A 1 218 PRO 218 524 524 PRO PRO A . n A 1 219 ILE 219 525 525 ILE ILE A . n A 1 220 THR 220 526 526 THR THR A . n A 1 221 ALA 221 527 527 ALA ALA A . n A 1 222 TYR 222 528 528 TYR TYR A . n A 1 223 ASP 223 529 529 ASP ASP A . n A 1 224 PRO 224 530 530 PRO PRO A . n A 1 225 ARG 225 531 531 ARG ARG A . n A 1 226 SER 226 532 532 SER SER A . n A 1 227 CYS 227 533 533 CYS CYS A . n A 1 228 SER 228 534 534 SER SER A . n A 1 229 GLN 229 535 535 GLN GLN A . n A 1 230 LYS 230 536 536 LYS LYS A . n A 1 231 LYS 231 537 537 LYS LYS A . n A 1 232 SER 232 538 538 SER SER A . n A 1 233 LEU 233 539 539 LEU LEU A . n A 1 234 VAL 234 540 540 VAL VAL A . n A 1 235 GLY 235 541 541 GLY GLY A . n A 1 236 VAL 236 542 542 VAL VAL A . n A 1 237 GLY 237 543 543 GLY GLY A . n A 1 238 GLU 238 544 544 GLU GLU A . n A 1 239 HIS 239 545 545 HIS HIS A . n A 1 240 CYS 240 546 546 CYS CYS A . n A 1 241 ALA 241 547 547 ALA ALA A . n A 1 242 GLY 242 548 548 GLY GLY A . n A 1 243 PHE 243 549 549 PHE PHE A . n A 1 244 GLY 244 550 550 GLY GLY A . n A 1 245 VAL 245 551 551 VAL VAL A . n A 1 246 ASP 246 552 552 ASP ASP A . n A 1 247 GLU 247 553 553 GLU GLU A . n A 1 248 GLU 248 554 554 GLU GLU A . n A 1 249 LYS 249 555 555 LYS LYS A . n A 1 250 CYS 250 556 556 CYS CYS A . n A 1 251 GLY 251 557 557 GLY GLY A . n A 1 252 VAL 252 558 558 VAL VAL A . n A 1 253 LEU 253 559 559 LEU LEU A . n A 1 254 ASP 254 560 560 ASP ASP A . n A 1 255 GLY 255 561 561 GLY GLY A . n A 1 256 SER 256 562 562 SER SER A . n A 1 257 TYR 257 563 563 TYR TYR A . n A 1 258 ASN 258 564 564 ASN ASN A . n A 1 259 VAL 259 565 565 VAL VAL A . n A 1 260 SER 260 566 566 SER SER A . n A 1 261 CYS 261 567 567 CYS CYS A . n A 1 262 LEU 262 568 568 LEU LEU A . n A 1 263 CYS 263 569 569 CYS CYS A . n A 1 264 SER 264 570 570 SER SER A . n A 1 265 THR 265 571 571 THR THR A . n A 1 266 ASP 266 572 572 ASP ASP A . n A 1 267 ALA 267 573 573 ALA ALA A . n A 1 268 PHE 268 574 574 PHE PHE A . n A 1 269 LEU 269 575 575 LEU LEU A . n A 1 270 GLY 270 576 576 GLY GLY A . n A 1 271 TRP 271 577 577 TRP TRP A . n A 1 272 SER 272 578 578 SER SER A . n A 1 273 TYR 273 579 579 TYR TYR A . n A 1 274 ASP 274 580 580 ASP ASP A . n A 1 275 THR 275 581 581 THR THR A . n A 1 276 CYS 276 582 582 CYS CYS A . n A 1 277 VAL 277 583 583 VAL VAL A . n A 1 278 SER 278 584 584 SER SER A . n A 1 279 ASN 279 585 585 ASN ASN A . n A 1 280 ASN 280 586 586 ASN ASN A . n A 1 281 ARG 281 587 587 ARG ARG A . n A 1 282 CYS 282 588 588 CYS CYS A . n A 1 283 ASN 283 589 589 ASN ASN A . n A 1 284 ILE 284 590 590 ILE ILE A . n A 1 285 PHE 285 591 591 PHE PHE A . n A 1 286 SER 286 592 592 SER SER A . n A 1 287 ASN 287 593 593 ASN ASN A . n A 1 288 PHE 288 594 594 PHE PHE A . n A 1 289 ILE 289 595 595 ILE ILE A . n A 1 290 LEU 290 596 596 LEU LEU A . n A 1 291 ASN 291 597 597 ASN ASN A . n A 1 292 GLY 292 598 598 GLY GLY A . n A 1 293 ILE 293 599 599 ILE ILE A . n A 1 294 ASN 294 600 600 ASN ASN A . n A 1 295 SER 295 601 601 SER SER A . n A 1 296 GLY 296 602 602 GLY GLY A . n A 1 297 THR 297 603 603 THR THR A . n A 1 298 THR 298 604 604 THR THR A . n A 1 299 CYS 299 605 605 CYS CYS A . n A 1 300 SER 300 606 606 SER SER A . n A 1 301 ASN 301 607 607 ASN ASN A . n A 1 302 ASP 302 608 608 ASP ASP A . n A 1 303 LEU 303 609 609 LEU LEU A . n A 1 304 LEU 304 610 610 LEU LEU A . n A 1 305 GLN 305 611 611 GLN GLN A . n A 1 306 PRO 306 612 612 PRO PRO A . n A 1 307 ASN 307 613 613 ASN ASN A . n A 1 308 THR 308 614 614 THR THR A . n A 1 309 GLU 309 615 615 GLU GLU A . n A 1 310 VAL 310 616 616 VAL VAL A . n A 1 311 PHE 311 617 617 PHE PHE A . n A 1 312 THR 312 618 618 THR THR A . n A 1 313 ASP 313 619 619 ASP ASP A . n A 1 314 VAL 314 620 620 VAL VAL A . n A 1 315 CYS 315 621 621 CYS CYS A . n A 1 316 VAL 316 622 622 VAL VAL A . n A 1 317 ASP 317 623 623 ASP ASP A . n A 1 318 TYR 318 624 624 TYR TYR A . n A 1 319 ASP 319 625 625 ASP ASP A . n A 1 320 LEU 320 626 626 LEU LEU A . n A 1 321 TYR 321 627 627 TYR TYR A . n A 1 322 GLY 322 628 628 GLY GLY A . n A 1 323 ILE 323 629 629 ILE ILE A . n A 1 324 THR 324 630 630 THR THR A . n A 1 325 GLY 325 631 631 GLY GLY A . n A 1 326 GLN 326 632 632 GLN GLN A . n A 1 327 GLY 327 633 633 GLY GLY A . n A 1 328 ILE 328 634 634 ILE ILE A . n A 1 329 PHE 329 635 635 PHE PHE A . n A 1 330 LYS 330 636 636 LYS LYS A . n A 1 331 GLU 331 637 637 GLU GLU A . n A 1 332 VAL 332 638 638 VAL VAL A . n A 1 333 SER 333 639 639 SER SER A . n A 1 334 ALA 334 640 640 ALA ALA A . n A 1 335 VAL 335 641 641 VAL VAL A . n A 1 336 TYR 336 642 642 TYR TYR A . n A 1 337 TYR 337 643 643 TYR TYR A . n A 1 338 ASN 338 644 644 ASN ASN A . n A 1 339 SER 339 645 645 SER SER A . n A 1 340 TRP 340 646 646 TRP TRP A . n A 1 341 GLN 341 647 647 GLN GLN A . n A 1 342 ASN 342 648 648 ASN ASN A . n A 1 343 LEU 343 649 649 LEU LEU A . n A 1 344 LEU 344 650 650 LEU LEU A . n A 1 345 TYR 345 651 651 TYR TYR A . n A 1 346 ASP 346 652 652 ASP ASP A . n A 1 347 SER 347 653 653 SER SER A . n A 1 348 ASN 348 654 654 ASN ALA A . n A 1 349 GLY 349 655 655 GLY GLY A . n A 1 350 ASN 350 656 656 ASN ASN A . n A 1 351 ILE 351 657 657 ILE ILE A . n A 1 352 ILE 352 658 658 ILE ILE A . n A 1 353 GLY 353 659 659 GLY GLY A . n A 1 354 PHE 354 660 660 PHE PHE A . n A 1 355 LYS 355 661 661 LYS LYS A . n A 1 356 ASP 356 662 662 ASP ASP A . n A 1 357 PHE 357 663 663 PHE PHE A . n A 1 358 VAL 358 664 664 VAL VAL A . n A 1 359 THR 359 665 665 THR THR A . n A 1 360 ASN 360 666 666 ASN ASN A . n A 1 361 LYS 361 667 667 LYS LYS A . n A 1 362 THR 362 668 668 THR THR A . n A 1 363 TYR 363 669 669 TYR TYR A . n A 1 364 ASN 364 670 670 ASN ASN A . n A 1 365 ILE 365 671 671 ILE ILE A . n A 1 366 PHE 366 672 672 PHE PHE A . n A 1 367 PRO 367 673 673 PRO PRO A . n A 1 368 CYS 368 674 674 CYS CYS A . n A 1 369 TYR 369 675 ? ? ? A . n A 1 370 ALA 370 676 ? ? ? A . n A 1 371 GLY 371 677 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 701 5 NAG NAG A . C 2 NAG 1 702 6 NAG NAG A . D 2 NAG 1 703 7 NAG NAG A . E 2 NAG 1 704 8 NAG NAG A . F 3 HOH 1 801 197 HOH HOH A . F 3 HOH 2 802 224 HOH HOH A . F 3 HOH 3 803 24 HOH HOH A . F 3 HOH 4 804 21 HOH HOH A . F 3 HOH 5 805 161 HOH HOH A . F 3 HOH 6 806 204 HOH HOH A . F 3 HOH 7 807 223 HOH HOH A . F 3 HOH 8 808 45 HOH HOH A . F 3 HOH 9 809 166 HOH HOH A . F 3 HOH 10 810 199 HOH HOH A . F 3 HOH 11 811 3 HOH HOH A . F 3 HOH 12 812 35 HOH HOH A . F 3 HOH 13 813 150 HOH HOH A . F 3 HOH 14 814 233 HOH HOH A . F 3 HOH 15 815 201 HOH HOH A . F 3 HOH 16 816 11 HOH HOH A . F 3 HOH 17 817 70 HOH HOH A . F 3 HOH 18 818 17 HOH HOH A . F 3 HOH 19 819 200 HOH HOH A . F 3 HOH 20 820 209 HOH HOH A . F 3 HOH 21 821 40 HOH HOH A . F 3 HOH 22 822 126 HOH HOH A . F 3 HOH 23 823 226 HOH HOH A . F 3 HOH 24 824 29 HOH HOH A . F 3 HOH 25 825 143 HOH HOH A . F 3 HOH 26 826 82 HOH HOH A . F 3 HOH 27 827 77 HOH HOH A . F 3 HOH 28 828 58 HOH HOH A . F 3 HOH 29 829 86 HOH HOH A . F 3 HOH 30 830 61 HOH HOH A . F 3 HOH 31 831 2 HOH HOH A . F 3 HOH 32 832 14 HOH HOH A . F 3 HOH 33 833 15 HOH HOH A . F 3 HOH 34 834 18 HOH HOH A . F 3 HOH 35 835 20 HOH HOH A . F 3 HOH 36 836 75 HOH HOH A . F 3 HOH 37 837 51 HOH HOH A . F 3 HOH 38 838 7 HOH HOH A . F 3 HOH 39 839 219 HOH HOH A . F 3 HOH 40 840 68 HOH HOH A . F 3 HOH 41 841 81 HOH HOH A . F 3 HOH 42 842 170 HOH HOH A . F 3 HOH 43 843 54 HOH HOH A . F 3 HOH 44 844 50 HOH HOH A . F 3 HOH 45 845 184 HOH HOH A . F 3 HOH 46 846 107 HOH HOH A . F 3 HOH 47 847 227 HOH HOH A . F 3 HOH 48 848 37 HOH HOH A . F 3 HOH 49 849 63 HOH HOH A . F 3 HOH 50 850 25 HOH HOH A . F 3 HOH 51 851 214 HOH HOH A . F 3 HOH 52 852 173 HOH HOH A . F 3 HOH 53 853 5 HOH HOH A . F 3 HOH 54 854 47 HOH HOH A . F 3 HOH 55 855 103 HOH HOH A . F 3 HOH 56 856 27 HOH HOH A . F 3 HOH 57 857 74 HOH HOH A . F 3 HOH 58 858 122 HOH HOH A . F 3 HOH 59 859 171 HOH HOH A . F 3 HOH 60 860 6 HOH HOH A . F 3 HOH 61 861 101 HOH HOH A . F 3 HOH 62 862 73 HOH HOH A . F 3 HOH 63 863 65 HOH HOH A . F 3 HOH 64 864 202 HOH HOH A . F 3 HOH 65 865 83 HOH HOH A . F 3 HOH 66 866 41 HOH HOH A . F 3 HOH 67 867 72 HOH HOH A . F 3 HOH 68 868 10 HOH HOH A . F 3 HOH 69 869 16 HOH HOH A . F 3 HOH 70 870 157 HOH HOH A . F 3 HOH 71 871 215 HOH HOH A . F 3 HOH 72 872 123 HOH HOH A . F 3 HOH 73 873 148 HOH HOH A . F 3 HOH 74 874 146 HOH HOH A . F 3 HOH 75 875 67 HOH HOH A . F 3 HOH 76 876 135 HOH HOH A . F 3 HOH 77 877 44 HOH HOH A . F 3 HOH 78 878 32 HOH HOH A . F 3 HOH 79 879 205 HOH HOH A . F 3 HOH 80 880 110 HOH HOH A . F 3 HOH 81 881 49 HOH HOH A . F 3 HOH 82 882 38 HOH HOH A . F 3 HOH 83 883 90 HOH HOH A . F 3 HOH 84 884 88 HOH HOH A . F 3 HOH 85 885 193 HOH HOH A . F 3 HOH 86 886 128 HOH HOH A . F 3 HOH 87 887 152 HOH HOH A . F 3 HOH 88 888 89 HOH HOH A . F 3 HOH 89 889 8 HOH HOH A . F 3 HOH 90 890 130 HOH HOH A . F 3 HOH 91 891 92 HOH HOH A . F 3 HOH 92 892 181 HOH HOH A . F 3 HOH 93 893 39 HOH HOH A . F 3 HOH 94 894 28 HOH HOH A . F 3 HOH 95 895 121 HOH HOH A . F 3 HOH 96 896 138 HOH HOH A . F 3 HOH 97 897 104 HOH HOH A . F 3 HOH 98 898 132 HOH HOH A . F 3 HOH 99 899 175 HOH HOH A . F 3 HOH 100 900 91 HOH HOH A . F 3 HOH 101 901 213 HOH HOH A . F 3 HOH 102 902 34 HOH HOH A . F 3 HOH 103 903 113 HOH HOH A . F 3 HOH 104 904 62 HOH HOH A . F 3 HOH 105 905 212 HOH HOH A . F 3 HOH 106 906 108 HOH HOH A . F 3 HOH 107 907 112 HOH HOH A . F 3 HOH 108 908 52 HOH HOH A . F 3 HOH 109 909 116 HOH HOH A . F 3 HOH 110 910 165 HOH HOH A . F 3 HOH 111 911 230 HOH HOH A . F 3 HOH 112 912 120 HOH HOH A . F 3 HOH 113 913 139 HOH HOH A . F 3 HOH 114 914 36 HOH HOH A . F 3 HOH 115 915 22 HOH HOH A . F 3 HOH 116 916 95 HOH HOH A . F 3 HOH 117 917 155 HOH HOH A . F 3 HOH 118 918 33 HOH HOH A . F 3 HOH 119 919 131 HOH HOH A . F 3 HOH 120 920 46 HOH HOH A . F 3 HOH 121 921 142 HOH HOH A . F 3 HOH 122 922 179 HOH HOH A . F 3 HOH 123 923 174 HOH HOH A . F 3 HOH 124 924 141 HOH HOH A . F 3 HOH 125 925 229 HOH HOH A . F 3 HOH 126 926 231 HOH HOH A . F 3 HOH 127 927 42 HOH HOH A . F 3 HOH 128 928 186 HOH HOH A . F 3 HOH 129 929 217 HOH HOH A . F 3 HOH 130 930 60 HOH HOH A . F 3 HOH 131 931 106 HOH HOH A . F 3 HOH 132 932 1 HOH HOH A . F 3 HOH 133 933 19 HOH HOH A . F 3 HOH 134 934 125 HOH HOH A . F 3 HOH 135 935 79 HOH HOH A . F 3 HOH 136 936 80 HOH HOH A . F 3 HOH 137 937 55 HOH HOH A . F 3 HOH 138 938 13 HOH HOH A . F 3 HOH 139 939 225 HOH HOH A . F 3 HOH 140 940 85 HOH HOH A . F 3 HOH 141 941 220 HOH HOH A . F 3 HOH 142 942 105 HOH HOH A . F 3 HOH 143 943 102 HOH HOH A . F 3 HOH 144 944 111 HOH HOH A . F 3 HOH 145 945 64 HOH HOH A . F 3 HOH 146 946 114 HOH HOH A . F 3 HOH 147 947 211 HOH HOH A . F 3 HOH 148 948 96 HOH HOH A . F 3 HOH 149 949 98 HOH HOH A . F 3 HOH 150 950 48 HOH HOH A . F 3 HOH 151 951 30 HOH HOH A . F 3 HOH 152 952 191 HOH HOH A . F 3 HOH 153 953 9 HOH HOH A . F 3 HOH 154 954 147 HOH HOH A . F 3 HOH 155 955 145 HOH HOH A . F 3 HOH 156 956 97 HOH HOH A . F 3 HOH 157 957 208 HOH HOH A . F 3 HOH 158 958 100 HOH HOH A . F 3 HOH 159 959 218 HOH HOH A . F 3 HOH 160 960 129 HOH HOH A . F 3 HOH 161 961 109 HOH HOH A . F 3 HOH 162 962 196 HOH HOH A . F 3 HOH 163 963 159 HOH HOH A . F 3 HOH 164 964 76 HOH HOH A . F 3 HOH 165 965 26 HOH HOH A . F 3 HOH 166 966 127 HOH HOH A . F 3 HOH 167 967 151 HOH HOH A . F 3 HOH 168 968 136 HOH HOH A . F 3 HOH 169 969 228 HOH HOH A . F 3 HOH 170 970 56 HOH HOH A . F 3 HOH 171 971 78 HOH HOH A . F 3 HOH 172 972 115 HOH HOH A . F 3 HOH 173 973 153 HOH HOH A . F 3 HOH 174 974 164 HOH HOH A . F 3 HOH 175 975 234 HOH HOH A . F 3 HOH 176 976 23 HOH HOH A . F 3 HOH 177 977 169 HOH HOH A . F 3 HOH 178 978 71 HOH HOH A . F 3 HOH 179 979 178 HOH HOH A . F 3 HOH 180 980 4 HOH HOH A . F 3 HOH 181 981 154 HOH HOH A . F 3 HOH 182 982 99 HOH HOH A . F 3 HOH 183 983 59 HOH HOH A . F 3 HOH 184 984 124 HOH HOH A . F 3 HOH 185 985 57 HOH HOH A . F 3 HOH 186 986 134 HOH HOH A . F 3 HOH 187 987 66 HOH HOH A . F 3 HOH 188 988 84 HOH HOH A . F 3 HOH 189 989 222 HOH HOH A . F 3 HOH 190 990 12 HOH HOH A . F 3 HOH 191 991 195 HOH HOH A . F 3 HOH 192 992 119 HOH HOH A . F 3 HOH 193 993 221 HOH HOH A . F 3 HOH 194 994 206 HOH HOH A . F 3 HOH 195 995 69 HOH HOH A . F 3 HOH 196 996 185 HOH HOH A . F 3 HOH 197 997 210 HOH HOH A . F 3 HOH 198 998 87 HOH HOH A . F 3 HOH 199 999 43 HOH HOH A . F 3 HOH 200 1000 188 HOH HOH A . F 3 HOH 201 1001 176 HOH HOH A . F 3 HOH 202 1002 158 HOH HOH A . F 3 HOH 203 1003 216 HOH HOH A . F 3 HOH 204 1004 31 HOH HOH A . F 3 HOH 205 1005 194 HOH HOH A . F 3 HOH 206 1006 162 HOH HOH A . F 3 HOH 207 1007 94 HOH HOH A . F 3 HOH 208 1008 232 HOH HOH A . F 3 HOH 209 1009 160 HOH HOH A . F 3 HOH 210 1010 190 HOH HOH A . F 3 HOH 211 1011 189 HOH HOH A . F 3 HOH 212 1012 140 HOH HOH A . F 3 HOH 213 1013 156 HOH HOH A . F 3 HOH 214 1014 167 HOH HOH A . F 3 HOH 215 1015 149 HOH HOH A . F 3 HOH 216 1016 198 HOH HOH A . F 3 HOH 217 1017 117 HOH HOH A . F 3 HOH 218 1018 163 HOH HOH A . F 3 HOH 219 1019 183 HOH HOH A . F 3 HOH 220 1020 192 HOH HOH A . F 3 HOH 221 1021 118 HOH HOH A . F 3 HOH 222 1022 172 HOH HOH A . F 3 HOH 223 1023 180 HOH HOH A . F 3 HOH 224 1024 168 HOH HOH A . F 3 HOH 225 1025 182 HOH HOH A . F 3 HOH 226 1026 133 HOH HOH A . F 3 HOH 227 1027 203 HOH HOH A . F 3 HOH 228 1028 207 HOH HOH A . F 3 HOH 229 1029 53 HOH HOH A . F 3 HOH 230 1030 144 HOH HOH A . F 3 HOH 231 1031 93 HOH HOH A . F 3 HOH 232 1032 177 HOH HOH A . F 3 HOH 233 1033 187 HOH HOH A . F 3 HOH 234 1034 137 HOH HOH A . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 860 ? 1 MORE 12 ? 1 'SSA (A^2)' 18850 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_special_symmetry.id _pdbx_struct_special_symmetry.PDB_model_num _pdbx_struct_special_symmetry.auth_asym_id _pdbx_struct_special_symmetry.auth_comp_id _pdbx_struct_special_symmetry.auth_seq_id _pdbx_struct_special_symmetry.PDB_ins_code _pdbx_struct_special_symmetry.label_asym_id _pdbx_struct_special_symmetry.label_comp_id _pdbx_struct_special_symmetry.label_seq_id 1 1 A HOH 980 ? F HOH . 2 1 A HOH 1002 ? F HOH . # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2017-06-07 2 'Structure model' 1 1 2017-06-14 3 'Structure model' 1 2 2017-09-27 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Structure summary' 2 3 'Structure model' 'Data collection' # loop_ _pdbx_audit_revision_category.ordinal _pdbx_audit_revision_category.revision_ordinal _pdbx_audit_revision_category.data_content_type _pdbx_audit_revision_category.category 1 2 'Structure model' struct 2 2 'Structure model' struct_keywords 3 3 'Structure model' diffrn_detector # loop_ _pdbx_audit_revision_item.ordinal _pdbx_audit_revision_item.revision_ordinal _pdbx_audit_revision_item.data_content_type _pdbx_audit_revision_item.item 1 2 'Structure model' '_struct.title' 2 2 'Structure model' '_struct_keywords.text' 3 3 'Structure model' '_diffrn_detector.detector' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.10.1_2155: ???)' 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? XDS ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? SHELXCD ? ? ? . 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 HO3 A NAG 702 ? ? O A HOH 802 ? ? 1.36 2 1 O A LYS 312 ? ? HD22 A ASN 600 ? ? 1.55 3 1 HH21 A ARG 447 ? A O A HOH 810 ? ? 1.56 4 1 HH22 A ARG 531 ? ? O A HOH 812 ? ? 1.56 5 1 HE A ARG 320 ? ? O A HOH 815 ? ? 1.58 6 1 O A HOH 906 ? ? O A HOH 928 ? ? 1.84 7 1 OD1 A ASP 326 ? ? O A HOH 801 ? ? 1.92 8 1 O A HOH 913 ? ? O A HOH 1010 ? ? 1.92 9 1 O3 A NAG 702 ? ? O A HOH 802 ? ? 1.94 10 1 O A HOH 890 ? ? O A HOH 1007 ? ? 1.99 11 1 OD1 A ASN 451 ? A O A HOH 803 ? ? 2.03 12 1 OD2 A ASP 366 ? B O A HOH 804 ? ? 2.06 13 1 OG A SER 562 ? ? OD1 A ASN 564 ? A 2.09 14 1 OE1 A GLU 554 ? ? O A HOH 805 ? ? 2.13 15 1 OG1 A THR 507 ? ? O A HOH 806 ? ? 2.15 16 1 O4 A NAG 702 ? ? O A HOH 807 ? ? 2.17 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASN A 343 ? ? -107.27 51.98 2 1 HIS A 364 ? ? -58.06 77.89 3 1 ASN A 413 ? ? -132.96 -57.91 4 1 ASN A 451 ? ? -105.49 -72.46 5 1 ASN A 451 ? ? -105.00 -73.11 6 1 SER A 456 ? ? -49.14 155.52 7 1 VAL A 509 ? ? -171.16 115.61 8 1 CYS A 520 ? ? 72.79 31.64 9 1 SER A 562 ? ? -101.94 -168.83 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ASN 654 ? CG ? A ASN 348 CG 2 1 Y 1 A ASN 654 ? OD1 ? A ASN 348 OD1 3 1 Y 1 A ASN 654 ? ND2 ? A ASN 348 ND2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A SER 307 ? A SER 1 2 1 Y 1 A GLY 308 ? A GLY 2 3 1 Y 1 A PHE 309 ? A PHE 3 4 1 Y 1 A THR 310 ? A THR 4 5 1 Y 1 A TYR 675 ? A TYR 369 6 1 Y 1 A ALA 676 ? A ALA 370 7 1 Y 1 A GLY 677 ? A GLY 371 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 water HOH #