data_5EUK # _entry.id 5EUK # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.288 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5EUK WWPDB D_1000215532 # _pdbx_database_related.content_type unspecified _pdbx_database_related.db_id 5ESQ _pdbx_database_related.db_name PDB _pdbx_database_related.details . # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5EUK _pdbx_database_status.recvd_initial_deposition_date 2015-11-18 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Bzymek, K.P.' 1 'Williams, J.C.' 2 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Acta Crystallogr F Struct Biol Commun' _citation.journal_id_ASTM ACSFEN _citation.journal_id_CSD ? _citation.journal_id_ISSN 2053-230X _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 72 _citation.language ? _citation.page_first 820 _citation.page_last 830 _citation.title 'Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.' _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1107/S2053230X16016149 _citation.pdbx_database_id_PubMed 27834791 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Bzymek, K.P.' 1 primary 'Avery, K.A.' 2 primary 'Ma, Y.' 3 primary 'Horne, D.A.' 4 primary 'Williams, J.C.' 5 # _cell.angle_alpha 90.00 _cell.angle_alpha_esd ? _cell.angle_beta 90.00 _cell.angle_beta_esd ? _cell.angle_gamma 90.00 _cell.angle_gamma_esd ? _cell.entry_id 5EUK _cell.details ? _cell.formula_units_Z ? _cell.length_a 63.930 _cell.length_a_esd ? _cell.length_b 82.060 _cell.length_b_esd ? _cell.length_c 212.090 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 8 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 5EUK _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Cetuximab Fab light chain' 23287.705 2 ? ? ? ? 2 polymer man 'Cetuximab Fab heavy chain' 23638.426 2 ? ? ? ? 3 polymer syn 'F3H meditope' 1463.729 2 ? ? ? ? 4 non-polymer syn 'PHOSPHATE ION' 94.971 4 ? ? ? ? 5 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 2 ? ? ? ? 6 non-polymer syn MESO-ERYTHRITOL 122.120 1 ? ? ? ? 7 water nat water 18.015 410 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVES EDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA ; ;DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVES EDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA ; A,C ? 2 'polypeptide(L)' no no ;QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFF KMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK ; ;QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFF KMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK ; B,D ? 3 'polypeptide(L)' no no CQHDLSTRRLKC CQHDLSTRRLKC E,F ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ASP n 1 2 ILE n 1 3 LEU n 1 4 LEU n 1 5 THR n 1 6 GLN n 1 7 SER n 1 8 PRO n 1 9 VAL n 1 10 ILE n 1 11 LEU n 1 12 SER n 1 13 VAL n 1 14 SER n 1 15 PRO n 1 16 GLY n 1 17 GLU n 1 18 ARG n 1 19 VAL n 1 20 SER n 1 21 PHE n 1 22 SER n 1 23 CYS n 1 24 ARG n 1 25 ALA n 1 26 SER n 1 27 GLN n 1 28 SER n 1 29 ILE n 1 30 GLY n 1 31 THR n 1 32 ASN n 1 33 ILE n 1 34 HIS n 1 35 TRP n 1 36 TYR n 1 37 GLN n 1 38 GLN n 1 39 ARG n 1 40 THR n 1 41 ASN n 1 42 GLY n 1 43 SER n 1 44 PRO n 1 45 ARG n 1 46 LEU n 1 47 LEU n 1 48 ILE n 1 49 LYS n 1 50 TYR n 1 51 ALA n 1 52 SER n 1 53 GLU n 1 54 SER n 1 55 ILE n 1 56 SER n 1 57 GLY n 1 58 ILE n 1 59 PRO n 1 60 SER n 1 61 ARG n 1 62 PHE n 1 63 SER n 1 64 GLY n 1 65 SER n 1 66 GLY n 1 67 SER n 1 68 GLY n 1 69 THR n 1 70 ASP n 1 71 PHE n 1 72 THR n 1 73 LEU n 1 74 SER n 1 75 ILE n 1 76 ASN n 1 77 SER n 1 78 VAL n 1 79 GLU n 1 80 SER n 1 81 GLU n 1 82 ASP n 1 83 ILE n 1 84 ALA n 1 85 ASP n 1 86 TYR n 1 87 TYR n 1 88 CYS n 1 89 GLN n 1 90 GLN n 1 91 ASN n 1 92 ASN n 1 93 ASN n 1 94 TRP n 1 95 PRO n 1 96 THR n 1 97 THR n 1 98 PHE n 1 99 GLY n 1 100 ALA n 1 101 GLY n 1 102 THR n 1 103 LYS n 1 104 LEU n 1 105 GLU n 1 106 LEU n 1 107 LYS n 1 108 ARG n 1 109 THR n 1 110 VAL n 1 111 ALA n 1 112 ALA n 1 113 PRO n 1 114 SER n 1 115 VAL n 1 116 PHE n 1 117 ILE n 1 118 PHE n 1 119 PRO n 1 120 PRO n 1 121 SER n 1 122 ASP n 1 123 GLU n 1 124 GLN n 1 125 LEU n 1 126 LYS n 1 127 SER n 1 128 GLY n 1 129 THR n 1 130 ALA n 1 131 SER n 1 132 VAL n 1 133 VAL n 1 134 CYS n 1 135 LEU n 1 136 LEU n 1 137 ASN n 1 138 ASN n 1 139 PHE n 1 140 TYR n 1 141 PRO n 1 142 ARG n 1 143 GLU n 1 144 ALA n 1 145 LYS n 1 146 VAL n 1 147 GLN n 1 148 TRP n 1 149 LYS n 1 150 VAL n 1 151 ASP n 1 152 ASN n 1 153 ALA n 1 154 LEU n 1 155 GLN n 1 156 SER n 1 157 GLY n 1 158 ASN n 1 159 SER n 1 160 GLN n 1 161 GLU n 1 162 SER n 1 163 VAL n 1 164 THR n 1 165 GLU n 1 166 GLN n 1 167 ASP n 1 168 SER n 1 169 LYS n 1 170 ASP n 1 171 SER n 1 172 THR n 1 173 TYR n 1 174 SER n 1 175 LEU n 1 176 SER n 1 177 SER n 1 178 THR n 1 179 LEU n 1 180 THR n 1 181 LEU n 1 182 SER n 1 183 LYS n 1 184 ALA n 1 185 ASP n 1 186 TYR n 1 187 GLU n 1 188 LYS n 1 189 HIS n 1 190 LYS n 1 191 VAL n 1 192 TYR n 1 193 ALA n 1 194 CYS n 1 195 GLU n 1 196 VAL n 1 197 THR n 1 198 HIS n 1 199 GLN n 1 200 GLY n 1 201 LEU n 1 202 SER n 1 203 SER n 1 204 PRO n 1 205 VAL n 1 206 THR n 1 207 LYS n 1 208 SER n 1 209 PHE n 1 210 ASN n 1 211 ARG n 1 212 GLY n 1 213 ALA n 2 1 GLN n 2 2 VAL n 2 3 GLN n 2 4 LEU n 2 5 LYS n 2 6 GLN n 2 7 SER n 2 8 GLY n 2 9 PRO n 2 10 GLY n 2 11 LEU n 2 12 VAL n 2 13 GLN n 2 14 PRO n 2 15 SER n 2 16 GLN n 2 17 SER n 2 18 LEU n 2 19 SER n 2 20 ILE n 2 21 THR n 2 22 CYS n 2 23 THR n 2 24 VAL n 2 25 SER n 2 26 GLY n 2 27 PHE n 2 28 SER n 2 29 LEU n 2 30 THR n 2 31 ASN n 2 32 TYR n 2 33 GLY n 2 34 VAL n 2 35 HIS n 2 36 TRP n 2 37 VAL n 2 38 ARG n 2 39 GLN n 2 40 SER n 2 41 PRO n 2 42 GLY n 2 43 LYS n 2 44 GLY n 2 45 LEU n 2 46 GLU n 2 47 TRP n 2 48 LEU n 2 49 GLY n 2 50 VAL n 2 51 ILE n 2 52 TRP n 2 53 SER n 2 54 GLY n 2 55 GLY n 2 56 ASN n 2 57 THR n 2 58 ASP n 2 59 TYR n 2 60 ASN n 2 61 THR n 2 62 PRO n 2 63 PHE n 2 64 THR n 2 65 SER n 2 66 ARG n 2 67 LEU n 2 68 SER n 2 69 ILE n 2 70 ASN n 2 71 LYS n 2 72 ASP n 2 73 ASN n 2 74 SER n 2 75 LYS n 2 76 SER n 2 77 GLN n 2 78 VAL n 2 79 PHE n 2 80 PHE n 2 81 LYS n 2 82 MET n 2 83 ASN n 2 84 SER n 2 85 LEU n 2 86 GLN n 2 87 SER n 2 88 ASN n 2 89 ASP n 2 90 THR n 2 91 ALA n 2 92 ILE n 2 93 TYR n 2 94 TYR n 2 95 CYS n 2 96 ALA n 2 97 ARG n 2 98 ALA n 2 99 LEU n 2 100 THR n 2 101 TYR n 2 102 TYR n 2 103 ASP n 2 104 TYR n 2 105 GLU n 2 106 PHE n 2 107 ALA n 2 108 TYR n 2 109 TRP n 2 110 GLY n 2 111 GLN n 2 112 GLY n 2 113 THR n 2 114 LEU n 2 115 VAL n 2 116 THR n 2 117 VAL n 2 118 SER n 2 119 ALA n 2 120 ALA n 2 121 SER n 2 122 THR n 2 123 LYS n 2 124 GLY n 2 125 PRO n 2 126 SER n 2 127 VAL n 2 128 PHE n 2 129 PRO n 2 130 LEU n 2 131 ALA n 2 132 PRO n 2 133 SER n 2 134 SER n 2 135 LYS n 2 136 SER n 2 137 THR n 2 138 SER n 2 139 GLY n 2 140 GLY n 2 141 THR n 2 142 ALA n 2 143 ALA n 2 144 LEU n 2 145 GLY n 2 146 CYS n 2 147 LEU n 2 148 VAL n 2 149 LYS n 2 150 ASP n 2 151 TYR n 2 152 PHE n 2 153 PRO n 2 154 GLU n 2 155 PRO n 2 156 VAL n 2 157 THR n 2 158 VAL n 2 159 SER n 2 160 TRP n 2 161 ASN n 2 162 SER n 2 163 GLY n 2 164 ALA n 2 165 LEU n 2 166 THR n 2 167 SER n 2 168 GLY n 2 169 VAL n 2 170 HIS n 2 171 THR n 2 172 PHE n 2 173 PRO n 2 174 ALA n 2 175 VAL n 2 176 LEU n 2 177 GLN n 2 178 SER n 2 179 SER n 2 180 GLY n 2 181 LEU n 2 182 TYR n 2 183 SER n 2 184 LEU n 2 185 SER n 2 186 SER n 2 187 VAL n 2 188 VAL n 2 189 THR n 2 190 VAL n 2 191 PRO n 2 192 SER n 2 193 SER n 2 194 SER n 2 195 LEU n 2 196 GLY n 2 197 THR n 2 198 GLN n 2 199 THR n 2 200 TYR n 2 201 ILE n 2 202 CYS n 2 203 ASN n 2 204 VAL n 2 205 ASN n 2 206 HIS n 2 207 LYS n 2 208 PRO n 2 209 SER n 2 210 ASN n 2 211 THR n 2 212 LYS n 2 213 VAL n 2 214 ASP n 2 215 LYS n 2 216 ARG n 2 217 VAL n 2 218 GLU n 2 219 PRO n 2 220 LYS n 3 1 CYS n 3 2 GLN n 3 3 HIS n 3 4 ASP n 3 5 LEU n 3 6 SER n 3 7 THR n 3 8 ARG n 3 9 ARG n 3 10 LEU n 3 11 LYS n 3 12 CYS n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 213 'mouse, human' ? ? ? ? ? ? ? ? 'MUS MUSCULUS, HOMO SAPIENS' '10090, 9606' ? ? ? ? ? ? ? ? unidentified 32644 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample 'Biological sequence' 1 220 'mouse, human' ? ? ? ? ? ? ? ? 'MUS MUSCULUS, HOMO SAPIENS' '10090, 9606' ? ? ? ? ? ? ? ? unidentified 32644 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # _pdbx_entity_src_syn.entity_id 3 _pdbx_entity_src_syn.pdbx_src_id 1 _pdbx_entity_src_syn.pdbx_alt_source_flag sample _pdbx_entity_src_syn.pdbx_beg_seq_num ? _pdbx_entity_src_syn.pdbx_end_seq_num ? _pdbx_entity_src_syn.organism_scientific 'synthetic construct' _pdbx_entity_src_syn.organism_common_name ? _pdbx_entity_src_syn.ncbi_taxonomy_id 32630 _pdbx_entity_src_syn.details ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 PDB 5EUK 5EUK ? 1 ? 1 2 PDB 5EUK 5EUK ? 2 ? 1 3 PDB 5EUK 5EUK ? 3 ? 1 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5EUK A 1 ? 213 ? 5EUK 1 ? 213 ? 1 213 2 2 5EUK B 1 ? 220 ? 5EUK 1 ? 220 ? 1 220 3 1 5EUK C 1 ? 213 ? 5EUK 1 ? 213 ? 1 213 4 2 5EUK D 1 ? 220 ? 5EUK 1 ? 220 ? 1 220 5 3 5EUK E 1 ? 12 ? 5EUK 1 ? 12 ? 1 12 6 3 5EUK F 1 ? 12 ? 5EUK 1 ? 12 ? 1 12 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MRY non-polymer . MESO-ERYTHRITOL ? 'C4 H10 O4' 122.120 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PO4 non-polymer . 'PHOSPHATE ION' ? 'O4 P -3' 94.971 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5EUK _exptl.crystals_number ? _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.87 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 57.20 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 5.3 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '0.1 M citric acid, 0.1 M sodium phosphate dibasic, 0.4 M potassium phosphate dibasic, 1.6 M sodium phosphate monobasic' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector 'IMAGE PLATE' _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'RIGAKU RAXIS IV++' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2013-10-07 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.5418 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source 'ROTATING ANODE' _diffrn_source.target ? _diffrn_source.type 'RIGAKU MICROMAX-007 HF' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 1.5418 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline ? _diffrn_source.pdbx_synchrotron_site ? # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5EUK _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.50 _reflns.d_resolution_low 32.83 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 39428 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 99.2 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 3.8 _reflns.pdbx_Rmerge_I_obs 0.126 _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 11.3 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _reflns_shell.d_res_high 2.5 _reflns_shell.d_res_low 2.56 _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs 1.8 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all 92.9 _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs 0.775 _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy 3.0 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? # _refine.aniso_B[1][1] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][2] ? _refine.aniso_B[2][3] ? _refine.aniso_B[3][3] ? _refine.B_iso_max ? _refine.B_iso_mean ? _refine.B_iso_min ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.details ? _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 5EUK _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 2.50 _refine.ls_d_res_low 32.83 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 39421 _refine.ls_number_reflns_R_free 1971 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 99.20 _refine.ls_percent_reflns_R_free 5.00 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.1746 _refine.ls_R_factor_R_free 0.2337 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.1714 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.36 _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model 4GW1 _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_R_Free_selection_details ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error 23.27 _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B ? _refine.overall_SU_ML 0.35 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6744 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 56 _refine_hist.number_atoms_solvent 410 _refine_hist.number_atoms_total 7210 _refine_hist.d_res_high 2.50 _refine_hist.d_res_low 32.83 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? 0.008 ? 6987 ? f_bond_d ? ? 'X-RAY DIFFRACTION' ? 1.193 ? 9507 ? f_angle_d ? ? 'X-RAY DIFFRACTION' ? 13.455 ? 2492 ? f_dihedral_angle_d ? ? 'X-RAY DIFFRACTION' ? 0.078 ? 1080 ? f_chiral_restr ? ? 'X-RAY DIFFRACTION' ? 0.005 ? 1212 ? f_plane_restr ? ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.R_factor_R_work _refine_ls_shell.redundancy_reflns_all _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.wR_factor_all _refine_ls_shell.wR_factor_obs _refine_ls_shell.wR_factor_R_free _refine_ls_shell.wR_factor_R_work _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.pdbx_phase_error _refine_ls_shell.pdbx_fsc_work _refine_ls_shell.pdbx_fsc_free 'X-RAY DIFFRACTION' 2.4950 2.5574 . . 130 2476 93.00 . . . 0.3686 . 0.2567 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.5574 2.6265 . . 138 2611 100.00 . . . 0.2969 . 0.2215 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.6265 2.7038 . . 139 2651 100.00 . . . 0.2817 . 0.2155 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.7038 2.7910 . . 141 2663 100.00 . . . 0.2895 . 0.2106 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.7910 2.8907 . . 140 2671 100.00 . . . 0.3005 . 0.2064 . . . . . . . . . . 'X-RAY DIFFRACTION' 2.8907 3.0064 . . 138 2623 100.00 . . . 0.2696 . 0.1914 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.0064 3.1431 . . 143 2704 100.00 . . . 0.2389 . 0.1800 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.1431 3.3086 . . 140 2663 100.00 . . . 0.2312 . 0.1750 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.3086 3.5157 . . 140 2663 100.00 . . . 0.2261 . 0.1609 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.5157 3.7868 . . 142 2695 100.00 . . . 0.2237 . 0.1572 . . . . . . . . . . 'X-RAY DIFFRACTION' 3.7868 4.1672 . . 142 2700 100.00 . . . 0.2213 . 0.1483 . . . . . . . . . . 'X-RAY DIFFRACTION' 4.1672 4.7686 . . 143 2720 100.00 . . . 0.1850 . 0.1262 . . . . . . . . . . 'X-RAY DIFFRACTION' 4.7686 6.0020 . . 145 2752 100.00 . . . 0.1860 . 0.1500 . . . . . . . . . . 'X-RAY DIFFRACTION' 6.0020 32.8363 . . 150 2858 98.00 . . . 0.2179 . 0.1838 . . . . . . . . . . # _struct.entry_id 5EUK _struct.title 'Cetuximab Fab in complex with F3H meditope variant' _struct.pdbx_descriptor 'Cetuximab Fab light chain, Cetuximab Fab heavy chain, F3H meditope' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5EUK _struct_keywords.text 'antibody, anti-EGFR, immune system' _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 1 ? D N N 2 ? E N N 3 ? F N N 3 ? G N N 4 ? H N N 4 ? I N N 5 ? J N N 4 ? K N N 6 ? L N N 5 ? M N N 4 ? N N N 7 ? O N N 7 ? P N N 7 ? Q N N 7 ? R N N 7 ? S N N 7 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 GLU A 79 ? ILE A 83 ? GLU A 79 ILE A 83 5 ? 5 HELX_P HELX_P2 AA2 SER A 121 ? LYS A 126 ? SER A 121 LYS A 126 1 ? 6 HELX_P HELX_P3 AA3 LYS A 183 ? LYS A 188 ? LYS A 183 LYS A 188 1 ? 6 HELX_P HELX_P4 AA4 THR B 61 ? THR B 64 ? THR B 61 THR B 64 5 ? 4 HELX_P HELX_P5 AA5 GLN B 86 ? THR B 90 ? GLN B 86 THR B 90 5 ? 5 HELX_P HELX_P6 AA6 SER B 162 ? ALA B 164 ? SER B 162 ALA B 164 5 ? 3 HELX_P HELX_P7 AA7 SER B 193 ? LEU B 195 ? SER B 193 LEU B 195 5 ? 3 HELX_P HELX_P8 AA8 LYS B 207 ? ASN B 210 ? LYS B 207 ASN B 210 5 ? 4 HELX_P HELX_P9 AA9 GLU C 79 ? ILE C 83 ? GLU C 79 ILE C 83 5 ? 5 HELX_P HELX_P10 AB1 SER C 121 ? LYS C 126 ? SER C 121 LYS C 126 1 ? 6 HELX_P HELX_P11 AB2 LYS C 183 ? LYS C 188 ? LYS C 183 LYS C 188 1 ? 6 HELX_P HELX_P12 AB3 THR D 61 ? THR D 64 ? THR D 61 THR D 64 5 ? 4 HELX_P HELX_P13 AB4 GLN D 86 ? THR D 90 ? GLN D 86 THR D 90 5 ? 5 HELX_P HELX_P14 AB5 SER D 162 ? ALA D 164 ? SER D 162 ALA D 164 5 ? 3 HELX_P HELX_P15 AB6 SER D 193 ? LEU D 195 ? SER D 193 LEU D 195 5 ? 3 HELX_P HELX_P16 AB7 LYS D 207 ? ASN D 210 ? LYS D 207 ASN D 210 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 23 SG ? ? ? 1_555 A CYS 88 SG ? ? A CYS 23 A CYS 88 1_555 ? ? ? ? ? ? ? 2.063 ? disulf2 disulf ? ? A CYS 134 SG ? ? ? 1_555 A CYS 194 SG ? ? A CYS 134 A CYS 194 1_555 ? ? ? ? ? ? ? 2.050 ? disulf3 disulf ? ? B CYS 22 SG ? ? ? 1_555 B CYS 95 SG ? ? B CYS 22 B CYS 95 1_555 ? ? ? ? ? ? ? 2.066 ? disulf4 disulf ? ? B CYS 146 SG ? ? ? 1_555 B CYS 202 SG ? ? B CYS 146 B CYS 202 1_555 ? ? ? ? ? ? ? 2.012 ? disulf5 disulf ? ? C CYS 23 SG ? ? ? 1_555 C CYS 88 SG ? ? C CYS 23 C CYS 88 1_555 ? ? ? ? ? ? ? 2.030 ? disulf6 disulf ? ? C CYS 134 SG ? ? ? 1_555 C CYS 194 SG ? ? C CYS 134 C CYS 194 1_555 ? ? ? ? ? ? ? 2.039 ? disulf7 disulf ? ? D CYS 22 SG ? ? ? 1_555 D CYS 95 SG ? ? D CYS 22 D CYS 95 1_555 ? ? ? ? ? ? ? 2.072 ? disulf8 disulf ? ? D CYS 146 SG ? ? ? 1_555 D CYS 202 SG ? ? D CYS 146 D CYS 202 1_555 ? ? ? ? ? ? ? 2.040 ? disulf9 disulf ? ? E CYS 1 SG ? ? ? 1_555 E CYS 12 SG ? ? E CYS 1 E CYS 12 1_555 ? ? ? ? ? ? ? 2.031 ? disulf10 disulf ? ? F CYS 1 SG ? ? ? 1_555 F CYS 12 SG ? ? F CYS 1 F CYS 12 1_555 ? ? ? ? ? ? ? 2.034 ? covale1 covale one ? B ASN 88 ND2 ? ? ? 1_555 I NAG . C1 ? ? B ASN 88 B NAG 301 1_555 ? ? ? ? ? ? ? 1.442 ? covale2 covale one ? D ASN 88 ND2 ? ? ? 1_555 L NAG . C1 ? ? D ASN 88 D NAG 301 1_555 ? ? ? ? ? ? ? 1.444 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 SER 7 A . ? SER 7 A PRO 8 A ? PRO 8 A 1 -10.20 2 TRP 94 A . ? TRP 94 A PRO 95 A ? PRO 95 A 1 -0.36 3 TYR 140 A . ? TYR 140 A PRO 141 A ? PRO 141 A 1 9.68 4 PHE 152 B . ? PHE 152 B PRO 153 B ? PRO 153 B 1 -8.37 5 GLU 154 B . ? GLU 154 B PRO 155 B ? PRO 155 B 1 0.34 6 SER 7 C . ? SER 7 C PRO 8 C ? PRO 8 C 1 -0.82 7 TRP 94 C . ? TRP 94 C PRO 95 C ? PRO 95 C 1 5.17 8 TYR 140 C . ? TYR 140 C PRO 141 C ? PRO 141 C 1 5.33 9 PHE 152 D . ? PHE 152 D PRO 153 D ? PRO 153 D 1 -4.30 10 GLU 154 D . ? GLU 154 D PRO 155 D ? PRO 155 D 1 -5.33 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 4 ? AA2 ? 5 ? AA3 ? 4 ? AA4 ? 4 ? AA5 ? 4 ? AA6 ? 4 ? AA7 ? 6 ? AA8 ? 4 ? AA9 ? 4 ? AB1 ? 4 ? AB2 ? 3 ? AB3 ? 4 ? AB4 ? 6 ? AB5 ? 4 ? AB6 ? 4 ? AB7 ? 4 ? AB8 ? 4 ? AB9 ? 6 ? AC1 ? 4 ? AC2 ? 4 ? AC3 ? 4 ? AC4 ? 3 ? AC5 ? 2 ? AC6 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? anti-parallel AA1 3 4 ? anti-parallel AA2 1 2 ? parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA2 4 5 ? anti-parallel AA3 1 2 ? parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA4 1 2 ? anti-parallel AA4 2 3 ? anti-parallel AA4 3 4 ? anti-parallel AA5 1 2 ? anti-parallel AA5 2 3 ? anti-parallel AA5 3 4 ? anti-parallel AA6 1 2 ? anti-parallel AA6 2 3 ? anti-parallel AA6 3 4 ? anti-parallel AA7 1 2 ? parallel AA7 2 3 ? anti-parallel AA7 3 4 ? anti-parallel AA7 4 5 ? anti-parallel AA7 5 6 ? anti-parallel AA8 1 2 ? parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA9 1 2 ? anti-parallel AA9 2 3 ? anti-parallel AA9 3 4 ? anti-parallel AB1 1 2 ? anti-parallel AB1 2 3 ? anti-parallel AB1 3 4 ? anti-parallel AB2 1 2 ? anti-parallel AB2 2 3 ? anti-parallel AB3 1 2 ? anti-parallel AB3 2 3 ? anti-parallel AB3 3 4 ? anti-parallel AB4 1 2 ? parallel AB4 2 3 ? anti-parallel AB4 3 4 ? anti-parallel AB4 4 5 ? anti-parallel AB4 5 6 ? anti-parallel AB5 1 2 ? parallel AB5 2 3 ? anti-parallel AB5 3 4 ? anti-parallel AB6 1 2 ? anti-parallel AB6 2 3 ? anti-parallel AB6 3 4 ? anti-parallel AB7 1 2 ? anti-parallel AB7 2 3 ? anti-parallel AB7 3 4 ? anti-parallel AB8 1 2 ? anti-parallel AB8 2 3 ? anti-parallel AB8 3 4 ? anti-parallel AB9 1 2 ? parallel AB9 2 3 ? anti-parallel AB9 3 4 ? anti-parallel AB9 4 5 ? anti-parallel AB9 5 6 ? anti-parallel AC1 1 2 ? parallel AC1 2 3 ? anti-parallel AC1 3 4 ? anti-parallel AC2 1 2 ? anti-parallel AC2 2 3 ? anti-parallel AC2 3 4 ? anti-parallel AC3 1 2 ? anti-parallel AC3 2 3 ? anti-parallel AC3 3 4 ? anti-parallel AC4 1 2 ? anti-parallel AC4 2 3 ? anti-parallel AC5 1 2 ? anti-parallel AC6 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 LEU A 4 ? SER A 7 ? LEU A 4 SER A 7 AA1 2 VAL A 19 ? ALA A 25 ? VAL A 19 ALA A 25 AA1 3 ASP A 70 ? ILE A 75 ? ASP A 70 ILE A 75 AA1 4 PHE A 62 ? SER A 67 ? PHE A 62 SER A 67 AA2 1 ILE A 10 ? VAL A 13 ? ILE A 10 VAL A 13 AA2 2 THR A 102 ? LEU A 106 ? THR A 102 LEU A 106 AA2 3 ALA A 84 ? GLN A 90 ? ALA A 84 GLN A 90 AA2 4 ILE A 33 ? GLN A 38 ? ILE A 33 GLN A 38 AA2 5 ARG A 45 ? ILE A 48 ? ARG A 45 ILE A 48 AA3 1 ILE A 10 ? VAL A 13 ? ILE A 10 VAL A 13 AA3 2 THR A 102 ? LEU A 106 ? THR A 102 LEU A 106 AA3 3 ALA A 84 ? GLN A 90 ? ALA A 84 GLN A 90 AA3 4 THR A 97 ? PHE A 98 ? THR A 97 PHE A 98 AA4 1 SER A 114 ? PHE A 118 ? SER A 114 PHE A 118 AA4 2 THR A 129 ? PHE A 139 ? THR A 129 PHE A 139 AA4 3 TYR A 173 ? SER A 182 ? TYR A 173 SER A 182 AA4 4 SER A 159 ? VAL A 163 ? SER A 159 VAL A 163 AA5 1 ALA A 153 ? GLN A 155 ? ALA A 153 GLN A 155 AA5 2 LYS A 145 ? VAL A 150 ? LYS A 145 VAL A 150 AA5 3 VAL A 191 ? THR A 197 ? VAL A 191 THR A 197 AA5 4 VAL A 205 ? ASN A 210 ? VAL A 205 ASN A 210 AA6 1 GLN B 3 ? GLN B 6 ? GLN B 3 GLN B 6 AA6 2 LEU B 18 ? SER B 25 ? LEU B 18 SER B 25 AA6 3 GLN B 77 ? MET B 82 ? GLN B 77 MET B 82 AA6 4 LEU B 67 ? ASP B 72 ? LEU B 67 ASP B 72 AA7 1 GLY B 10 ? VAL B 12 ? GLY B 10 VAL B 12 AA7 2 THR B 113 ? VAL B 117 ? THR B 113 VAL B 117 AA7 3 ALA B 91 ? ALA B 98 ? ALA B 91 ALA B 98 AA7 4 VAL B 34 ? SER B 40 ? VAL B 34 SER B 40 AA7 5 GLY B 44 ? ILE B 51 ? GLY B 44 ILE B 51 AA7 6 THR B 57 ? TYR B 59 ? THR B 57 TYR B 59 AA8 1 GLY B 10 ? VAL B 12 ? GLY B 10 VAL B 12 AA8 2 THR B 113 ? VAL B 117 ? THR B 113 VAL B 117 AA8 3 ALA B 91 ? ALA B 98 ? ALA B 91 ALA B 98 AA8 4 PHE B 106 ? TRP B 109 ? PHE B 106 TRP B 109 AA9 1 SER B 126 ? LEU B 130 ? SER B 126 LEU B 130 AA9 2 THR B 141 ? TYR B 151 ? THR B 141 TYR B 151 AA9 3 TYR B 182 ? PRO B 191 ? TYR B 182 PRO B 191 AA9 4 VAL B 169 ? THR B 171 ? VAL B 169 THR B 171 AB1 1 THR B 137 ? SER B 138 ? THR B 137 SER B 138 AB1 2 THR B 141 ? TYR B 151 ? THR B 141 TYR B 151 AB1 3 TYR B 182 ? PRO B 191 ? TYR B 182 PRO B 191 AB1 4 VAL B 175 ? LEU B 176 ? VAL B 175 LEU B 176 AB2 1 THR B 157 ? TRP B 160 ? THR B 157 TRP B 160 AB2 2 ILE B 201 ? HIS B 206 ? ILE B 201 HIS B 206 AB2 3 THR B 211 ? ARG B 216 ? THR B 211 ARG B 216 AB3 1 LEU C 4 ? SER C 7 ? LEU C 4 SER C 7 AB3 2 VAL C 19 ? ALA C 25 ? VAL C 19 ALA C 25 AB3 3 ASP C 70 ? ILE C 75 ? ASP C 70 ILE C 75 AB3 4 PHE C 62 ? SER C 67 ? PHE C 62 SER C 67 AB4 1 ILE C 10 ? VAL C 13 ? ILE C 10 VAL C 13 AB4 2 THR C 102 ? LEU C 106 ? THR C 102 LEU C 106 AB4 3 ASP C 85 ? GLN C 90 ? ASP C 85 GLN C 90 AB4 4 ILE C 33 ? GLN C 38 ? ILE C 33 GLN C 38 AB4 5 ARG C 45 ? LYS C 49 ? ARG C 45 LYS C 49 AB4 6 GLU C 53 ? SER C 54 ? GLU C 53 SER C 54 AB5 1 ILE C 10 ? VAL C 13 ? ILE C 10 VAL C 13 AB5 2 THR C 102 ? LEU C 106 ? THR C 102 LEU C 106 AB5 3 ASP C 85 ? GLN C 90 ? ASP C 85 GLN C 90 AB5 4 THR C 97 ? PHE C 98 ? THR C 97 PHE C 98 AB6 1 SER C 114 ? PHE C 118 ? SER C 114 PHE C 118 AB6 2 THR C 129 ? PHE C 139 ? THR C 129 PHE C 139 AB6 3 TYR C 173 ? SER C 182 ? TYR C 173 SER C 182 AB6 4 SER C 159 ? VAL C 163 ? SER C 159 VAL C 163 AB7 1 ALA C 153 ? LEU C 154 ? ALA C 153 LEU C 154 AB7 2 LYS C 145 ? VAL C 150 ? LYS C 145 VAL C 150 AB7 3 VAL C 191 ? THR C 197 ? VAL C 191 THR C 197 AB7 4 VAL C 205 ? ASN C 210 ? VAL C 205 ASN C 210 AB8 1 GLN D 3 ? GLN D 6 ? GLN D 3 GLN D 6 AB8 2 LEU D 18 ? SER D 25 ? LEU D 18 SER D 25 AB8 3 GLN D 77 ? MET D 82 ? GLN D 77 MET D 82 AB8 4 LEU D 67 ? ASP D 72 ? LEU D 67 ASP D 72 AB9 1 GLY D 10 ? VAL D 12 ? GLY D 10 VAL D 12 AB9 2 THR D 113 ? VAL D 117 ? THR D 113 VAL D 117 AB9 3 ALA D 91 ? ALA D 98 ? ALA D 91 ALA D 98 AB9 4 VAL D 34 ? SER D 40 ? VAL D 34 SER D 40 AB9 5 GLY D 44 ? ILE D 51 ? GLY D 44 ILE D 51 AB9 6 THR D 57 ? TYR D 59 ? THR D 57 TYR D 59 AC1 1 GLY D 10 ? VAL D 12 ? GLY D 10 VAL D 12 AC1 2 THR D 113 ? VAL D 117 ? THR D 113 VAL D 117 AC1 3 ALA D 91 ? ALA D 98 ? ALA D 91 ALA D 98 AC1 4 PHE D 106 ? TRP D 109 ? PHE D 106 TRP D 109 AC2 1 SER D 126 ? LEU D 130 ? SER D 126 LEU D 130 AC2 2 THR D 141 ? TYR D 151 ? THR D 141 TYR D 151 AC2 3 TYR D 182 ? PRO D 191 ? TYR D 182 PRO D 191 AC2 4 VAL D 169 ? THR D 171 ? VAL D 169 THR D 171 AC3 1 SER D 126 ? LEU D 130 ? SER D 126 LEU D 130 AC3 2 THR D 141 ? TYR D 151 ? THR D 141 TYR D 151 AC3 3 TYR D 182 ? PRO D 191 ? TYR D 182 PRO D 191 AC3 4 VAL D 175 ? LEU D 176 ? VAL D 175 LEU D 176 AC4 1 THR D 157 ? TRP D 160 ? THR D 157 TRP D 160 AC4 2 ILE D 201 ? HIS D 206 ? ILE D 201 HIS D 206 AC4 3 THR D 211 ? ARG D 216 ? THR D 211 ARG D 216 AC5 1 GLN E 2 ? ASP E 4 ? GLN E 2 ASP E 4 AC5 2 ARG E 9 ? LYS E 11 ? ARG E 9 LYS E 11 AC6 1 GLN F 2 ? ASP F 4 ? GLN F 2 ASP F 4 AC6 2 ARG F 9 ? LYS F 11 ? ARG F 9 LYS F 11 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N THR A 5 ? N THR A 5 O ARG A 24 ? O ARG A 24 AA1 2 3 N PHE A 21 ? N PHE A 21 O LEU A 73 ? O LEU A 73 AA1 3 4 O SER A 74 ? O SER A 74 N SER A 63 ? N SER A 63 AA2 1 2 N LEU A 11 ? N LEU A 11 O LYS A 103 ? O LYS A 103 AA2 2 3 O LEU A 104 ? O LEU A 104 N ALA A 84 ? N ALA A 84 AA2 3 4 O ASP A 85 ? O ASP A 85 N GLN A 38 ? N GLN A 38 AA2 4 5 N TRP A 35 ? N TRP A 35 O LEU A 47 ? O LEU A 47 AA3 1 2 N LEU A 11 ? N LEU A 11 O LYS A 103 ? O LYS A 103 AA3 2 3 O LEU A 104 ? O LEU A 104 N ALA A 84 ? N ALA A 84 AA3 3 4 N GLN A 90 ? N GLN A 90 O THR A 97 ? O THR A 97 AA4 1 2 N PHE A 118 ? N PHE A 118 O VAL A 133 ? O VAL A 133 AA4 2 3 N LEU A 136 ? N LEU A 136 O LEU A 175 ? O LEU A 175 AA4 3 4 O THR A 178 ? O THR A 178 N GLN A 160 ? N GLN A 160 AA5 1 2 O GLN A 155 ? O GLN A 155 N TRP A 148 ? N TRP A 148 AA5 2 3 N LYS A 149 ? N LYS A 149 O ALA A 193 ? O ALA A 193 AA5 3 4 N VAL A 196 ? N VAL A 196 O VAL A 205 ? O VAL A 205 AA6 1 2 N LYS B 5 ? N LYS B 5 O THR B 23 ? O THR B 23 AA6 2 3 N CYS B 22 ? N CYS B 22 O VAL B 78 ? O VAL B 78 AA6 3 4 O PHE B 79 ? O PHE B 79 N ASN B 70 ? N ASN B 70 AA7 1 2 N VAL B 12 ? N VAL B 12 O THR B 116 ? O THR B 116 AA7 2 3 O VAL B 115 ? O VAL B 115 N ALA B 91 ? N ALA B 91 AA7 3 4 O ALA B 96 ? O ALA B 96 N HIS B 35 ? N HIS B 35 AA7 4 5 N TRP B 36 ? N TRP B 36 O LEU B 48 ? O LEU B 48 AA7 5 6 N VAL B 50 ? N VAL B 50 O ASP B 58 ? O ASP B 58 AA8 1 2 N VAL B 12 ? N VAL B 12 O THR B 116 ? O THR B 116 AA8 2 3 O VAL B 115 ? O VAL B 115 N ALA B 91 ? N ALA B 91 AA8 3 4 N ARG B 97 ? N ARG B 97 O TYR B 108 ? O TYR B 108 AA9 1 2 N PHE B 128 ? N PHE B 128 O LEU B 147 ? O LEU B 147 AA9 2 3 N VAL B 148 ? N VAL B 148 O LEU B 184 ? O LEU B 184 AA9 3 4 O VAL B 187 ? O VAL B 187 N HIS B 170 ? N HIS B 170 AB1 1 2 N SER B 138 ? N SER B 138 O THR B 141 ? O THR B 141 AB1 2 3 N VAL B 148 ? N VAL B 148 O LEU B 184 ? O LEU B 184 AB1 3 4 O SER B 183 ? O SER B 183 N VAL B 175 ? N VAL B 175 AB2 1 2 N SER B 159 ? N SER B 159 O ASN B 203 ? O ASN B 203 AB2 2 3 N VAL B 204 ? N VAL B 204 O VAL B 213 ? O VAL B 213 AB3 1 2 N THR C 5 ? N THR C 5 O ARG C 24 ? O ARG C 24 AB3 2 3 N CYS C 23 ? N CYS C 23 O PHE C 71 ? O PHE C 71 AB3 3 4 O SER C 74 ? O SER C 74 N SER C 63 ? N SER C 63 AB4 1 2 N LEU C 11 ? N LEU C 11 O LYS C 103 ? O LYS C 103 AB4 2 3 O THR C 102 ? O THR C 102 N TYR C 86 ? N TYR C 86 AB4 3 4 O ASP C 85 ? O ASP C 85 N GLN C 38 ? N GLN C 38 AB4 4 5 N TRP C 35 ? N TRP C 35 O LEU C 47 ? O LEU C 47 AB4 5 6 N LYS C 49 ? N LYS C 49 O GLU C 53 ? O GLU C 53 AB5 1 2 N LEU C 11 ? N LEU C 11 O LYS C 103 ? O LYS C 103 AB5 2 3 O THR C 102 ? O THR C 102 N TYR C 86 ? N TYR C 86 AB5 3 4 N GLN C 90 ? N GLN C 90 O THR C 97 ? O THR C 97 AB6 1 2 N SER C 114 ? N SER C 114 O ASN C 137 ? O ASN C 137 AB6 2 3 N VAL C 132 ? N VAL C 132 O LEU C 179 ? O LEU C 179 AB6 3 4 O THR C 178 ? O THR C 178 N GLN C 160 ? N GLN C 160 AB7 1 2 O ALA C 153 ? O ALA C 153 N VAL C 150 ? N VAL C 150 AB7 2 3 N GLN C 147 ? N GLN C 147 O GLU C 195 ? O GLU C 195 AB7 3 4 N TYR C 192 ? N TYR C 192 O PHE C 209 ? O PHE C 209 AB8 1 2 N GLN D 3 ? N GLN D 3 O SER D 25 ? O SER D 25 AB8 2 3 N CYS D 22 ? N CYS D 22 O VAL D 78 ? O VAL D 78 AB8 3 4 O PHE D 79 ? O PHE D 79 N ASN D 70 ? N ASN D 70 AB9 1 2 N VAL D 12 ? N VAL D 12 O THR D 116 ? O THR D 116 AB9 2 3 O VAL D 115 ? O VAL D 115 N ALA D 91 ? N ALA D 91 AB9 3 4 O TYR D 94 ? O TYR D 94 N VAL D 37 ? N VAL D 37 AB9 4 5 N TRP D 36 ? N TRP D 36 O LEU D 48 ? O LEU D 48 AB9 5 6 N VAL D 50 ? N VAL D 50 O ASP D 58 ? O ASP D 58 AC1 1 2 N VAL D 12 ? N VAL D 12 O THR D 116 ? O THR D 116 AC1 2 3 O VAL D 115 ? O VAL D 115 N ALA D 91 ? N ALA D 91 AC1 3 4 N ARG D 97 ? N ARG D 97 O TYR D 108 ? O TYR D 108 AC2 1 2 N LEU D 130 ? N LEU D 130 O GLY D 145 ? O GLY D 145 AC2 2 3 N TYR D 151 ? N TYR D 151 O TYR D 182 ? O TYR D 182 AC2 3 4 O VAL D 187 ? O VAL D 187 N HIS D 170 ? N HIS D 170 AC3 1 2 N LEU D 130 ? N LEU D 130 O GLY D 145 ? O GLY D 145 AC3 2 3 N TYR D 151 ? N TYR D 151 O TYR D 182 ? O TYR D 182 AC3 3 4 O SER D 183 ? O SER D 183 N VAL D 175 ? N VAL D 175 AC4 1 2 N SER D 159 ? N SER D 159 O ASN D 203 ? O ASN D 203 AC4 2 3 N VAL D 204 ? N VAL D 204 O VAL D 213 ? O VAL D 213 AC5 1 2 N GLN E 2 ? N GLN E 2 O LYS E 11 ? O LYS E 11 AC6 1 2 N GLN F 2 ? N GLN F 2 O LYS F 11 ? O LYS F 11 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A PO4 301 ? 5 'binding site for residue PO4 A 301' AC2 Software A PO4 302 ? 8 'binding site for residue PO4 A 302' AC3 Software B PO4 302 ? 5 'binding site for residue PO4 B 302' AC4 Software C MRY 301 ? 7 'binding site for residue MRY C 301' AC5 Software D PO4 302 ? 4 'binding site for residue PO4 D 302' AC6 Software B NAG 301 ? 4 'binding site for Mono-Saccharide NAG B 301 bound to ASN B 88' AC7 Software D NAG 301 ? 5 'binding site for Mono-Saccharide NAG D 301 bound to ASN D 88' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 5 ARG A 39 ? ARG A 39 . ? 1_555 ? 2 AC1 5 ARG A 45 ? ARG A 45 . ? 1_555 ? 3 AC1 5 PRO A 59 ? PRO A 59 . ? 1_555 ? 4 AC1 5 ARG A 61 ? ARG A 61 . ? 1_555 ? 5 AC1 5 HOH N . ? HOH A 421 . ? 1_555 ? 6 AC2 8 GLN A 155 ? GLN A 155 . ? 1_555 ? 7 AC2 8 LEU A 181 ? LEU A 181 . ? 1_555 ? 8 AC2 8 ASP A 185 ? ASP A 185 . ? 1_555 ? 9 AC2 8 HIS A 189 ? HIS A 189 . ? 1_555 ? 10 AC2 8 ILE D 201 ? ILE D 201 . ? 3_545 ? 11 AC2 8 ASN D 203 ? ASN D 203 . ? 3_545 ? 12 AC2 8 ASP D 214 ? ASP D 214 . ? 3_545 ? 13 AC2 8 HOH Q . ? HOH D 423 . ? 3_545 ? 14 AC3 5 ASN B 205 ? ASN B 205 . ? 1_555 ? 15 AC3 5 LYS B 207 ? LYS B 207 . ? 1_555 ? 16 AC3 5 ASN B 210 ? ASN B 210 . ? 1_555 ? 17 AC3 5 LYS B 212 ? LYS B 212 . ? 1_555 ? 18 AC3 5 HOH O . ? HOH B 421 . ? 1_555 ? 19 AC4 7 SER C 156 ? SER C 156 . ? 1_555 ? 20 AC4 7 GLY C 157 ? GLY C 157 . ? 1_555 ? 21 AC4 7 ASN C 158 ? ASN C 158 . ? 1_555 ? 22 AC4 7 SER C 159 ? SER C 159 . ? 1_555 ? 23 AC4 7 HOH P . ? HOH C 410 . ? 1_555 ? 24 AC4 7 HOH P . ? HOH C 436 . ? 1_555 ? 25 AC4 7 HOH P . ? HOH C 489 . ? 1_555 ? 26 AC5 4 ASN D 205 ? ASN D 205 . ? 1_555 ? 27 AC5 4 LYS D 207 ? LYS D 207 . ? 1_555 ? 28 AC5 4 ASN D 210 ? ASN D 210 . ? 1_555 ? 29 AC5 4 LYS D 212 ? LYS D 212 . ? 1_555 ? 30 AC6 4 ARG B 38 ? ARG B 38 . ? 1_555 ? 31 AC6 4 LYS B 43 ? LYS B 43 . ? 1_555 ? 32 AC6 4 ASN B 88 ? ASN B 88 . ? 1_555 ? 33 AC6 4 HOH O . ? HOH B 434 . ? 1_555 ? 34 AC7 5 ARG D 38 ? ARG D 38 . ? 1_555 ? 35 AC7 5 SER D 40 ? SER D 40 . ? 1_555 ? 36 AC7 5 LYS D 43 ? LYS D 43 . ? 1_555 ? 37 AC7 5 ASN D 88 ? ASN D 88 . ? 1_555 ? 38 AC7 5 HOH Q . ? HOH D 417 . ? 1_555 ? # _atom_sites.entry_id 5EUK _atom_sites.fract_transf_matrix[1][1] 0.015642 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.012186 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.004715 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O P S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASP A 1 1 ? -14.296 -41.942 9.164 1.00 36.12 ? 1 ASP A N 1 ATOM 2 C CA . ASP A 1 1 ? -15.433 -41.071 9.444 1.00 30.43 ? 1 ASP A CA 1 ATOM 3 C C . ASP A 1 1 ? -15.007 -39.611 9.472 1.00 31.35 ? 1 ASP A C 1 ATOM 4 O O . ASP A 1 1 ? -13.860 -39.310 9.780 1.00 39.85 ? 1 ASP A O 1 ATOM 5 C CB . ASP A 1 1 ? -16.060 -41.423 10.794 1.00 35.69 ? 1 ASP A CB 1 ATOM 6 C CG . ASP A 1 1 ? -16.676 -42.816 10.818 1.00 41.55 ? 1 ASP A CG 1 ATOM 7 O OD1 . ASP A 1 1 ? -16.708 -43.463 9.748 1.00 34.07 ? 1 ASP A OD1 1 ATOM 8 O OD2 . ASP A 1 1 ? -17.143 -43.243 11.909 1.00 35.37 ? 1 ASP A OD2 1 ATOM 9 N N . ILE A 1 2 ? -15.922 -38.701 9.148 1.00 29.99 ? 2 ILE A N 1 ATOM 10 C CA . ILE A 1 2 ? -15.643 -37.286 9.338 1.00 30.78 ? 2 ILE A CA 1 ATOM 11 C C . ILE A 1 2 ? -15.605 -36.953 10.836 1.00 33.06 ? 2 ILE A C 1 ATOM 12 O O . ILE A 1 2 ? -16.539 -37.275 11.582 1.00 25.64 ? 2 ILE A O 1 ATOM 13 C CB . ILE A 1 2 ? -16.696 -36.379 8.671 1.00 32.71 ? 2 ILE A CB 1 ATOM 14 C CG1 . ILE A 1 2 ? -16.869 -36.750 7.203 1.00 33.97 ? 2 ILE A CG1 1 ATOM 15 C CG2 . ILE A 1 2 ? -16.286 -34.917 8.811 1.00 25.86 ? 2 ILE A CG2 1 ATOM 16 C CD1 . ILE A 1 2 ? -15.581 -36.741 6.437 1.00 27.50 ? 2 ILE A CD1 1 ATOM 17 N N . LEU A 1 3 ? -14.521 -36.319 11.271 1.00 31.71 ? 3 LEU A N 1 ATOM 18 C CA . LEU A 1 3 ? -14.421 -35.845 12.641 1.00 27.96 ? 3 LEU A CA 1 ATOM 19 C C . LEU A 1 3 ? -14.869 -34.384 12.704 1.00 30.91 ? 3 LEU A C 1 ATOM 20 O O . LEU A 1 3 ? -14.399 -33.531 11.946 1.00 27.23 ? 3 LEU A O 1 ATOM 21 C CB . LEU A 1 3 ? -13.000 -36.024 13.191 1.00 22.46 ? 3 LEU A CB 1 ATOM 22 C CG . LEU A 1 3 ? -12.701 -35.505 14.609 1.00 35.27 ? 3 LEU A CG 1 ATOM 23 C CD1 . LEU A 1 3 ? -13.367 -36.349 15.706 1.00 25.10 ? 3 LEU A CD1 1 ATOM 24 C CD2 . LEU A 1 3 ? -11.195 -35.401 14.857 1.00 29.39 ? 3 LEU A CD2 1 ATOM 25 N N . LEU A 1 4 ? -15.802 -34.114 13.606 1.00 21.75 ? 4 LEU A N 1 ATOM 26 C CA . LEU A 1 4 ? -16.293 -32.771 13.804 1.00 20.95 ? 4 LEU A CA 1 ATOM 27 C C . LEU A 1 4 ? -15.727 -32.256 15.108 1.00 28.80 ? 4 LEU A C 1 ATOM 28 O O . LEU A 1 4 ? -15.906 -32.874 16.162 1.00 24.94 ? 4 LEU A O 1 ATOM 29 C CB . LEU A 1 4 ? -17.819 -32.756 13.860 1.00 23.15 ? 4 LEU A CB 1 ATOM 30 C CG . LEU A 1 4 ? -18.531 -33.177 12.576 1.00 24.61 ? 4 LEU A CG 1 ATOM 31 C CD1 . LEU A 1 4 ? -20.045 -33.155 12.800 1.00 26.44 ? 4 LEU A CD1 1 ATOM 32 C CD2 . LEU A 1 4 ? -18.130 -32.274 11.405 1.00 16.92 ? 4 LEU A CD2 1 ATOM 33 N N . THR A 1 5 ? -15.039 -31.122 15.034 1.00 27.30 ? 5 THR A N 1 ATOM 34 C CA . THR A 1 5 ? -14.476 -30.525 16.220 1.00 24.98 ? 5 THR A CA 1 ATOM 35 C C . THR A 1 5 ? -15.246 -29.254 16.580 1.00 26.74 ? 5 THR A C 1 ATOM 36 O O . THR A 1 5 ? -15.310 -28.307 15.794 1.00 24.55 ? 5 THR A O 1 ATOM 37 C CB . THR A 1 5 ? -12.969 -30.256 16.033 1.00 30.60 ? 5 THR A CB 1 ATOM 38 O OG1 . THR A 1 5 ? -12.315 -31.500 15.751 1.00 24.00 ? 5 THR A OG1 1 ATOM 39 C CG2 . THR A 1 5 ? -12.369 -29.639 17.299 1.00 18.03 ? 5 THR A CG2 1 ATOM 40 N N . GLN A 1 6 ? -15.859 -29.265 17.763 1.00 28.62 ? 6 GLN A N 1 ATOM 41 C CA . GLN A 1 6 ? -16.609 -28.119 18.265 1.00 21.87 ? 6 GLN A CA 1 ATOM 42 C C . GLN A 1 6 ? -15.795 -27.386 19.309 1.00 26.33 ? 6 GLN A C 1 ATOM 43 O O . GLN A 1 6 ? -15.251 -27.997 20.227 1.00 21.43 ? 6 GLN A O 1 ATOM 44 C CB . GLN A 1 6 ? -17.934 -28.560 18.865 1.00 16.34 ? 6 GLN A CB 1 ATOM 45 C CG . GLN A 1 6 ? -18.874 -29.171 17.872 1.00 19.07 ? 6 GLN A CG 1 ATOM 46 C CD . GLN A 1 6 ? -20.262 -29.350 18.432 1.00 24.29 ? 6 GLN A CD 1 ATOM 47 O OE1 . GLN A 1 6 ? -20.772 -30.475 18.510 1.00 18.99 ? 6 GLN A OE1 1 ATOM 48 N NE2 . GLN A 1 6 ? -20.885 -28.242 18.842 1.00 16.07 ? 6 GLN A NE2 1 ATOM 49 N N . SER A 1 7 ? -15.699 -26.072 19.156 1.00 31.47 ? 7 SER A N 1 ATOM 50 C CA . SER A 1 7 ? -14.867 -25.268 20.041 1.00 36.01 ? 7 SER A CA 1 ATOM 51 C C . SER A 1 7 ? -15.532 -23.919 20.278 1.00 39.14 ? 7 SER A C 1 ATOM 52 O O . SER A 1 7 ? -16.311 -23.452 19.440 1.00 40.19 ? 7 SER A O 1 ATOM 53 C CB . SER A 1 7 ? -13.473 -25.061 19.438 1.00 36.87 ? 7 SER A CB 1 ATOM 54 O OG . SER A 1 7 ? -13.453 -23.924 18.594 1.00 46.40 ? 7 SER A OG 1 ATOM 55 N N . PRO A 1 8 ? -15.268 -23.311 21.441 1.00 36.42 ? 8 PRO A N 1 ATOM 56 C CA . PRO A 1 8 ? -14.568 -23.975 22.544 1.00 33.61 ? 8 PRO A CA 1 ATOM 57 C C . PRO A 1 8 ? -15.483 -24.975 23.237 1.00 35.57 ? 8 PRO A C 1 ATOM 58 O O . PRO A 1 8 ? -16.652 -25.119 22.866 1.00 35.64 ? 8 PRO A O 1 ATOM 59 C CB . PRO A 1 8 ? -14.291 -22.828 23.507 1.00 37.81 ? 8 PRO A CB 1 ATOM 60 C CG . PRO A 1 8 ? -15.419 -21.865 23.252 1.00 30.52 ? 8 PRO A CG 1 ATOM 61 C CD . PRO A 1 8 ? -15.632 -21.921 21.773 1.00 31.91 ? 8 PRO A CD 1 ATOM 62 N N . VAL A 1 9 ? -14.944 -25.649 24.241 1.00 27.82 ? 9 VAL A N 1 ATOM 63 C CA . VAL A 1 9 ? -15.710 -26.594 25.042 1.00 32.50 ? 9 VAL A CA 1 ATOM 64 C C . VAL A 1 9 ? -16.855 -25.921 25.833 1.00 30.91 ? 9 VAL A C 1 ATOM 65 O O . VAL A 1 9 ? -17.968 -26.448 25.903 1.00 24.44 ? 9 VAL A O 1 ATOM 66 C CB . VAL A 1 9 ? -14.755 -27.386 25.974 1.00 36.74 ? 9 VAL A CB 1 ATOM 67 C CG1 . VAL A 1 9 ? -15.370 -27.608 27.307 1.00 37.83 ? 9 VAL A CG1 1 ATOM 68 C CG2 . VAL A 1 9 ? -14.342 -28.708 25.344 1.00 26.31 ? 9 VAL A CG2 1 ATOM 69 N N . ILE A 1 10 ? -16.578 -24.754 26.417 1.00 31.64 ? 10 ILE A N 1 ATOM 70 C CA . ILE A 1 10 ? -17.582 -24.004 27.172 1.00 23.22 ? 10 ILE A CA 1 ATOM 71 C C . ILE A 1 10 ? -17.668 -22.571 26.679 1.00 21.83 ? 10 ILE A C 1 ATOM 72 O O . ILE A 1 10 ? -16.652 -21.940 26.410 1.00 28.41 ? 10 ILE A O 1 ATOM 73 C CB . ILE A 1 10 ? -17.236 -23.931 28.676 1.00 26.12 ? 10 ILE A CB 1 ATOM 74 C CG1 . ILE A 1 10 ? -16.944 -25.312 29.240 1.00 36.69 ? 10 ILE A CG1 1 ATOM 75 C CG2 . ILE A 1 10 ? -18.368 -23.318 29.471 1.00 25.34 ? 10 ILE A CG2 1 ATOM 76 C CD1 . ILE A 1 10 ? -16.548 -25.293 30.703 1.00 54.78 ? 10 ILE A CD1 1 ATOM 77 N N . LEU A 1 11 ? -18.886 -22.061 26.553 1.00 20.29 ? 11 LEU A N 1 ATOM 78 C CA . LEU A 1 11 ? -19.100 -20.633 26.365 1.00 22.53 ? 11 LEU A CA 1 ATOM 79 C C . LEU A 1 11 ? -19.887 -20.047 27.529 1.00 25.94 ? 11 LEU A C 1 ATOM 80 O O . LEU A 1 11 ? -20.869 -20.631 27.983 1.00 29.18 ? 11 LEU A O 1 ATOM 81 C CB . LEU A 1 11 ? -19.841 -20.365 25.060 1.00 18.38 ? 11 LEU A CB 1 ATOM 82 C CG . LEU A 1 11 ? -18.977 -20.449 23.804 1.00 25.81 ? 11 LEU A CG 1 ATOM 83 C CD1 . LEU A 1 11 ? -19.831 -20.321 22.554 1.00 26.49 ? 11 LEU A CD1 1 ATOM 84 C CD2 . LEU A 1 11 ? -17.908 -19.373 23.849 1.00 22.88 ? 11 LEU A CD2 1 ATOM 85 N N . SER A 1 12 ? -19.456 -18.887 28.006 1.00 29.25 ? 12 SER A N 1 ATOM 86 C CA . SER A 1 12 ? -20.142 -18.196 29.088 1.00 24.56 ? 12 SER A CA 1 ATOM 87 C C . SER A 1 12 ? -20.417 -16.750 28.681 1.00 25.34 ? 12 SER A C 1 ATOM 88 O O . SER A 1 12 ? -19.494 -15.973 28.500 1.00 31.89 ? 12 SER A O 1 ATOM 89 C CB . SER A 1 12 ? -19.283 -18.240 30.354 1.00 32.17 ? 12 SER A CB 1 ATOM 90 O OG . SER A 1 12 ? -19.793 -17.380 31.361 1.00 48.27 ? 12 SER A OG 1 ATOM 91 N N . VAL A 1 13 ? -21.685 -16.389 28.519 1.00 21.04 ? 13 VAL A N 1 ATOM 92 C CA . VAL A 1 13 ? -22.032 -15.038 28.086 1.00 26.47 ? 13 VAL A CA 1 ATOM 93 C C . VAL A 1 13 ? -23.118 -14.422 28.969 1.00 29.36 ? 13 VAL A C 1 ATOM 94 O O . VAL A 1 13 ? -23.740 -15.115 29.767 1.00 29.56 ? 13 VAL A O 1 ATOM 95 C CB . VAL A 1 13 ? -22.502 -15.017 26.600 1.00 30.79 ? 13 VAL A CB 1 ATOM 96 C CG1 . VAL A 1 13 ? -21.559 -15.834 25.709 1.00 26.20 ? 13 VAL A CG1 1 ATOM 97 C CG2 . VAL A 1 13 ? -23.900 -15.547 26.478 1.00 21.03 ? 13 VAL A CG2 1 ATOM 98 N N . SER A 1 14 ? -23.346 -13.121 28.819 1.00 27.74 ? 14 SER A N 1 ATOM 99 C CA . SER A 1 14 ? -24.423 -12.452 29.539 1.00 28.76 ? 14 SER A CA 1 ATOM 100 C C . SER A 1 14 ? -25.655 -12.329 28.647 1.00 29.35 ? 14 SER A C 1 ATOM 101 O O . SER A 1 14 ? -25.531 -12.294 27.430 1.00 32.96 ? 14 SER A O 1 ATOM 102 C CB . SER A 1 14 ? -23.962 -11.082 30.011 1.00 30.13 ? 14 SER A CB 1 ATOM 103 O OG . SER A 1 14 ? -22.684 -11.173 30.626 1.00 37.45 ? 14 SER A OG 1 ATOM 104 N N . PRO A 1 15 ? -26.854 -12.279 29.246 1.00 27.42 ? 15 PRO A N 1 ATOM 105 C CA . PRO A 1 15 ? -28.077 -12.204 28.436 1.00 32.97 ? 15 PRO A CA 1 ATOM 106 C C . PRO A 1 15 ? -28.079 -10.994 27.522 1.00 31.71 ? 15 PRO A C 1 ATOM 107 O O . PRO A 1 15 ? -27.487 -9.972 27.861 1.00 35.25 ? 15 PRO A O 1 ATOM 108 C CB . PRO A 1 15 ? -29.182 -12.057 29.480 1.00 24.00 ? 15 PRO A CB 1 ATOM 109 C CG . PRO A 1 15 ? -28.607 -12.660 30.701 1.00 22.06 ? 15 PRO A CG 1 ATOM 110 C CD . PRO A 1 15 ? -27.153 -12.354 30.685 1.00 23.59 ? 15 PRO A CD 1 ATOM 111 N N . GLY A 1 16 ? -28.727 -11.128 26.367 1.00 37.57 ? 16 GLY A N 1 ATOM 112 C CA . GLY A 1 16 ? -28.801 -10.061 25.394 1.00 31.61 ? 16 GLY A CA 1 ATOM 113 C C . GLY A 1 16 ? -27.591 -9.991 24.487 1.00 33.00 ? 16 GLY A C 1 ATOM 114 O O . GLY A 1 16 ? -27.653 -9.344 23.444 1.00 40.65 ? 16 GLY A O 1 ATOM 115 N N . GLU A 1 17 ? -26.491 -10.633 24.885 1.00 25.89 ? 17 GLU A N 1 ATOM 116 C CA . GLU A 1 17 ? -25.287 -10.678 24.062 1.00 34.56 ? 17 GLU A CA 1 ATOM 117 C C . GLU A 1 17 ? -25.438 -11.675 22.914 1.00 36.40 ? 17 GLU A C 1 ATOM 118 O O . GLU A 1 17 ? -26.265 -12.584 22.969 1.00 29.73 ? 17 GLU A O 1 ATOM 119 C CB . GLU A 1 17 ? -24.051 -11.027 24.901 1.00 30.92 ? 17 GLU A CB 1 ATOM 120 C CG . GLU A 1 17 ? -23.517 -9.889 25.762 1.00 43.60 ? 17 GLU A CG 1 ATOM 121 C CD . GLU A 1 17 ? -22.387 -10.336 26.683 1.00 51.53 ? 17 GLU A CD 1 ATOM 122 O OE1 . GLU A 1 17 ? -21.966 -11.507 26.568 1.00 43.52 ? 17 GLU A OE1 1 ATOM 123 O OE2 . GLU A 1 17 ? -21.926 -9.521 27.520 1.00 46.26 ? 17 GLU A OE2 1 ATOM 124 N N . ARG A 1 18 ? -24.633 -11.488 21.875 1.00 32.96 ? 18 ARG A N 1 ATOM 125 C CA . ARG A 1 18 ? -24.608 -12.406 20.750 1.00 33.96 ? 18 ARG A CA 1 ATOM 126 C C . ARG A 1 18 ? -23.578 -13.487 21.046 1.00 31.00 ? 18 ARG A C 1 ATOM 127 O O . ARG A 1 18 ? -22.573 -13.225 21.712 1.00 31.34 ? 18 ARG A O 1 ATOM 128 C CB . ARG A 1 18 ? -24.248 -11.664 19.462 1.00 38.38 ? 18 ARG A CB 1 ATOM 129 C CG . ARG A 1 18 ? -24.420 -12.489 18.206 1.00 44.85 ? 18 ARG A CG 1 ATOM 130 C CD . ARG A 1 18 ? -24.084 -11.717 16.944 1.00 48.77 ? 18 ARG A CD 1 ATOM 131 N NE . ARG A 1 18 ? -24.257 -12.552 15.753 1.00 61.93 ? 18 ARG A NE 1 ATOM 132 C CZ . ARG A 1 18 ? -25.326 -12.519 14.956 1.00 65.98 ? 18 ARG A CZ 1 ATOM 133 N NH1 . ARG A 1 18 ? -26.320 -11.676 15.208 1.00 57.99 ? 18 ARG A NH1 1 ATOM 134 N NH2 . ARG A 1 18 ? -25.394 -13.317 13.891 1.00 51.92 ? 18 ARG A NH2 1 ATOM 135 N N . VAL A 1 19 ? -23.829 -14.701 20.561 1.00 27.93 ? 19 VAL A N 1 ATOM 136 C CA . VAL A 1 19 ? -22.901 -15.812 20.774 1.00 33.57 ? 19 VAL A CA 1 ATOM 137 C C . VAL A 1 19 ? -22.792 -16.727 19.543 1.00 23.12 ? 19 VAL A C 1 ATOM 138 O O . VAL A 1 19 ? -23.772 -16.941 18.812 1.00 26.46 ? 19 VAL A O 1 ATOM 139 C CB . VAL A 1 19 ? -23.265 -16.630 22.063 1.00 24.82 ? 19 VAL A CB 1 ATOM 140 C CG1 . VAL A 1 19 ? -24.458 -17.506 21.836 1.00 20.53 ? 19 VAL A CG1 1 ATOM 141 C CG2 . VAL A 1 19 ? -22.079 -17.467 22.528 1.00 25.65 ? 19 VAL A CG2 1 ATOM 142 N N . SER A 1 20 ? -21.594 -17.254 19.316 1.00 19.70 ? 20 SER A N 1 ATOM 143 C CA . SER A 1 20 ? -21.321 -18.104 18.160 1.00 23.11 ? 20 SER A CA 1 ATOM 144 C C . SER A 1 20 ? -20.646 -19.414 18.548 1.00 27.60 ? 20 SER A C 1 ATOM 145 O O . SER A 1 20 ? -19.714 -19.441 19.353 1.00 26.51 ? 20 SER A O 1 ATOM 146 C CB . SER A 1 20 ? -20.445 -17.377 17.134 1.00 22.96 ? 20 SER A CB 1 ATOM 147 O OG . SER A 1 20 ? -21.186 -16.364 16.478 1.00 33.25 ? 20 SER A OG 1 ATOM 148 N N . PHE A 1 21 ? -21.132 -20.498 17.959 1.00 25.30 ? 21 PHE A N 1 ATOM 149 C CA . PHE A 1 21 ? -20.567 -21.815 18.165 1.00 27.38 ? 21 PHE A CA 1 ATOM 150 C C . PHE A 1 21 ? -19.882 -22.270 16.879 1.00 31.12 ? 21 PHE A C 1 ATOM 151 O O . PHE A 1 21 ? -20.421 -22.137 15.781 1.00 24.11 ? 21 PHE A O 1 ATOM 152 C CB . PHE A 1 21 ? -21.657 -22.814 18.545 1.00 27.04 ? 21 PHE A CB 1 ATOM 153 C CG . PHE A 1 21 ? -22.479 -22.404 19.740 1.00 25.59 ? 21 PHE A CG 1 ATOM 154 C CD1 . PHE A 1 21 ? -23.603 -21.613 19.590 1.00 20.86 ? 21 PHE A CD1 1 ATOM 155 C CD2 . PHE A 1 21 ? -22.137 -22.830 21.014 1.00 26.82 ? 21 PHE A CD2 1 ATOM 156 C CE1 . PHE A 1 21 ? -24.366 -21.245 20.694 1.00 26.91 ? 21 PHE A CE1 1 ATOM 157 C CE2 . PHE A 1 21 ? -22.892 -22.464 22.114 1.00 22.97 ? 21 PHE A CE2 1 ATOM 158 C CZ . PHE A 1 21 ? -24.012 -21.671 21.952 1.00 20.17 ? 21 PHE A CZ 1 ATOM 159 N N . SER A 1 22 ? -18.690 -22.820 17.043 1.00 30.54 ? 22 SER A N 1 ATOM 160 C CA . SER A 1 22 ? -17.835 -23.192 15.941 1.00 22.76 ? 22 SER A CA 1 ATOM 161 C C . SER A 1 22 ? -17.898 -24.709 15.715 1.00 28.34 ? 22 SER A C 1 ATOM 162 O O . SER A 1 22 ? -17.775 -25.490 16.662 1.00 28.02 ? 22 SER A O 1 ATOM 163 C CB . SER A 1 22 ? -16.415 -22.732 16.289 1.00 19.60 ? 22 SER A CB 1 ATOM 164 O OG . SER A 1 22 ? -15.441 -23.218 15.402 1.00 34.07 ? 22 SER A OG 1 ATOM 165 N N . CYS A 1 23 ? -18.107 -25.130 14.468 1.00 24.79 ? 23 CYS A N 1 ATOM 166 C CA . CYS A 1 23 ? -18.023 -26.551 14.128 1.00 23.33 ? 23 CYS A CA 1 ATOM 167 C C . CYS A 1 23 ? -17.095 -26.733 12.948 1.00 28.44 ? 23 CYS A C 1 ATOM 168 O O . CYS A 1 23 ? -17.391 -26.289 11.841 1.00 29.97 ? 23 CYS A O 1 ATOM 169 C CB . CYS A 1 23 ? -19.399 -27.138 13.800 1.00 23.87 ? 23 CYS A CB 1 ATOM 170 S SG . CYS A 1 23 ? -19.409 -28.934 13.503 1.00 27.34 ? 23 CYS A SG 1 ATOM 171 N N . ARG A 1 24 ? -15.967 -27.387 13.184 1.00 25.85 ? 24 ARG A N 1 ATOM 172 C CA . ARG A 1 24 ? -14.999 -27.604 12.121 1.00 24.79 ? 24 ARG A CA 1 ATOM 173 C C . ARG A 1 24 ? -14.898 -29.068 11.709 1.00 25.74 ? 24 ARG A C 1 ATOM 174 O O . ARG A 1 24 ? -14.826 -29.963 12.552 1.00 24.83 ? 24 ARG A O 1 ATOM 175 C CB . ARG A 1 24 ? -13.631 -27.042 12.509 1.00 23.21 ? 24 ARG A CB 1 ATOM 176 C CG . ARG A 1 24 ? -13.621 -25.538 12.659 1.00 31.31 ? 24 ARG A CG 1 ATOM 177 C CD . ARG A 1 24 ? -12.284 -25.010 13.166 1.00 35.98 ? 24 ARG A CD 1 ATOM 178 N NE . ARG A 1 24 ? -12.133 -23.602 12.808 1.00 38.65 ? 24 ARG A NE 1 ATOM 179 C CZ . ARG A 1 24 ? -12.552 -22.586 13.559 1.00 37.77 ? 24 ARG A CZ 1 ATOM 180 N NH1 . ARG A 1 24 ? -13.127 -22.812 14.740 1.00 39.31 ? 24 ARG A NH1 1 ATOM 181 N NH2 . ARG A 1 24 ? -12.388 -21.340 13.132 1.00 31.46 ? 24 ARG A NH2 1 ATOM 182 N N . ALA A 1 25 ? -14.891 -29.292 10.400 1.00 26.25 ? 25 ALA A N 1 ATOM 183 C CA . ALA A 1 25 ? -14.846 -30.637 9.841 1.00 27.22 ? 25 ALA A CA 1 ATOM 184 C C . ALA A 1 25 ? -13.439 -31.040 9.389 1.00 28.34 ? 25 ALA A C 1 ATOM 185 O O . ALA A 1 25 ? -12.653 -30.208 8.938 1.00 30.52 ? 25 ALA A O 1 ATOM 186 C CB . ALA A 1 25 ? -15.831 -30.749 8.685 1.00 24.00 ? 25 ALA A CB 1 ATOM 187 N N . SER A 1 26 ? -13.134 -32.327 9.502 1.00 28.16 ? 26 SER A N 1 ATOM 188 C CA . SER A 1 26 ? -11.813 -32.846 9.160 1.00 27.04 ? 26 SER A CA 1 ATOM 189 C C . SER A 1 26 ? -11.583 -32.940 7.654 1.00 28.91 ? 26 SER A C 1 ATOM 190 O O . SER A 1 26 ? -10.514 -33.339 7.210 1.00 30.70 ? 26 SER A O 1 ATOM 191 C CB . SER A 1 26 ? -11.629 -34.230 9.787 1.00 33.24 ? 26 SER A CB 1 ATOM 192 O OG . SER A 1 26 ? -12.649 -35.125 9.342 1.00 35.23 ? 26 SER A OG 1 ATOM 193 N N . GLN A 1 27 ? -12.581 -32.540 6.878 1.00 32.77 ? 27 GLN A N 1 ATOM 194 C CA . GLN A 1 27 ? -12.614 -32.817 5.454 1.00 36.32 ? 27 GLN A CA 1 ATOM 195 C C . GLN A 1 27 ? -13.820 -32.063 4.918 1.00 35.69 ? 27 GLN A C 1 ATOM 196 O O . GLN A 1 27 ? -14.830 -31.972 5.603 1.00 32.72 ? 27 GLN A O 1 ATOM 197 C CB . GLN A 1 27 ? -12.804 -34.316 5.285 1.00 37.42 ? 27 GLN A CB 1 ATOM 198 C CG . GLN A 1 27 ? -12.708 -34.865 3.903 1.00 33.86 ? 27 GLN A CG 1 ATOM 199 C CD . GLN A 1 27 ? -12.957 -36.368 3.898 1.00 43.19 ? 27 GLN A CD 1 ATOM 200 O OE1 . GLN A 1 27 ? -12.659 -37.063 4.874 1.00 38.37 ? 27 GLN A OE1 1 ATOM 201 N NE2 . GLN A 1 27 ? -13.517 -36.871 2.808 1.00 47.82 ? 27 GLN A NE2 1 ATOM 202 N N . SER A 1 28 ? -13.726 -31.503 3.717 1.00 36.60 ? 28 SER A N 1 ATOM 203 C CA . SER A 1 28 ? -14.815 -30.667 3.215 1.00 37.46 ? 28 SER A CA 1 ATOM 204 C C . SER A 1 28 ? -16.129 -31.441 3.164 1.00 35.15 ? 28 SER A C 1 ATOM 205 O O . SER A 1 28 ? -16.152 -32.600 2.765 1.00 38.60 ? 28 SER A O 1 ATOM 206 C CB . SER A 1 28 ? -14.474 -30.084 1.846 1.00 35.79 ? 28 SER A CB 1 ATOM 207 O OG . SER A 1 28 ? -15.520 -29.241 1.392 1.00 37.53 ? 28 SER A OG 1 ATOM 208 N N . ILE A 1 29 ? -17.214 -30.809 3.598 1.00 37.00 ? 29 ILE A N 1 ATOM 209 C CA . ILE A 1 29 ? -18.510 -31.486 3.665 1.00 31.27 ? 29 ILE A CA 1 ATOM 210 C C . ILE A 1 29 ? -19.632 -30.628 3.119 1.00 31.83 ? 29 ILE A C 1 ATOM 211 O O . ILE A 1 29 ? -20.804 -30.894 3.394 1.00 27.40 ? 29 ILE A O 1 ATOM 212 C CB . ILE A 1 29 ? -18.898 -31.901 5.108 1.00 26.56 ? 29 ILE A CB 1 ATOM 213 C CG1 . ILE A 1 29 ? -18.819 -30.697 6.056 1.00 28.12 ? 29 ILE A CG1 1 ATOM 214 C CG2 . ILE A 1 29 ? -18.035 -33.048 5.591 1.00 27.64 ? 29 ILE A CG2 1 ATOM 215 C CD1 . ILE A 1 29 ? -19.373 -30.964 7.449 1.00 20.73 ? 29 ILE A CD1 1 ATOM 216 N N . GLY A 1 30 ? -19.266 -29.598 2.356 1.00 32.41 ? 30 GLY A N 1 ATOM 217 C CA . GLY A 1 30 ? -20.236 -28.749 1.686 1.00 24.34 ? 30 GLY A CA 1 ATOM 218 C C . GLY A 1 30 ? -20.989 -27.880 2.669 1.00 29.20 ? 30 GLY A C 1 ATOM 219 O O . GLY A 1 30 ? -20.379 -27.160 3.447 1.00 29.87 ? 30 GLY A O 1 ATOM 220 N N . THR A 1 31 ? -22.314 -27.939 2.625 1.00 26.40 ? 31 THR A N 1 ATOM 221 C CA . THR A 1 31 ? -23.138 -27.279 3.625 1.00 27.23 ? 31 THR A CA 1 ATOM 222 C C . THR A 1 31 ? -23.991 -28.336 4.303 1.00 27.43 ? 31 THR A C 1 ATOM 223 O O . THR A 1 31 ? -25.075 -28.049 4.815 1.00 27.88 ? 31 THR A O 1 ATOM 224 C CB . THR A 1 31 ? -24.074 -26.218 3.005 1.00 26.15 ? 31 THR A CB 1 ATOM 225 O OG1 . THR A 1 31 ? -24.722 -26.768 1.854 1.00 25.03 ? 31 THR A OG1 1 ATOM 226 C CG2 . THR A 1 31 ? -23.299 -24.979 2.599 1.00 22.67 ? 31 THR A CG2 1 ATOM 227 N N . ASN A 1 32 ? -23.509 -29.571 4.270 1.00 24.66 ? 32 ASN A N 1 ATOM 228 C CA . ASN A 1 32 ? -24.251 -30.674 4.848 1.00 21.09 ? 32 ASN A CA 1 ATOM 229 C C . ASN A 1 32 ? -24.009 -30.765 6.345 1.00 25.71 ? 32 ASN A C 1 ATOM 230 O O . ASN A 1 32 ? -23.440 -31.736 6.837 1.00 24.23 ? 32 ASN A O 1 ATOM 231 C CB . ASN A 1 32 ? -23.889 -31.990 4.162 1.00 20.99 ? 32 ASN A CB 1 ATOM 232 C CG . ASN A 1 32 ? -25.078 -32.912 4.023 1.00 26.73 ? 32 ASN A CG 1 ATOM 233 O OD1 . ASN A 1 32 ? -25.801 -33.173 4.991 1.00 26.52 ? 32 ASN A OD1 1 ATOM 234 N ND2 . ASN A 1 32 ? -25.303 -33.400 2.809 1.00 25.40 ? 32 ASN A ND2 1 ATOM 235 N N . ILE A 1 33 ? -24.436 -29.736 7.064 1.00 26.42 ? 33 ILE A N 1 ATOM 236 C CA A ILE A 1 33 ? -24.304 -29.707 8.510 0.59 26.78 ? 33 ILE A CA 1 ATOM 237 C CA B ILE A 1 33 ? -24.304 -29.725 8.512 0.41 26.60 ? 33 ILE A CA 1 ATOM 238 C C . ILE A 1 33 ? -25.642 -29.343 9.162 1.00 27.19 ? 33 ILE A C 1 ATOM 239 O O . ILE A 1 33 ? -26.394 -28.511 8.649 1.00 21.24 ? 33 ILE A O 1 ATOM 240 C CB A ILE A 1 33 ? -23.162 -28.750 8.952 0.59 25.96 ? 33 ILE A CB 1 ATOM 241 C CB B ILE A 1 33 ? -23.165 -28.787 8.970 0.41 26.60 ? 33 ILE A CB 1 ATOM 242 C CG1 A ILE A 1 33 ? -22.607 -29.152 10.317 0.59 25.99 ? 33 ILE A CG1 1 ATOM 243 C CG1 B ILE A 1 33 ? -22.899 -28.934 10.466 0.41 25.95 ? 33 ILE A CG1 1 ATOM 244 C CG2 A ILE A 1 33 ? -23.608 -27.297 8.946 0.59 25.83 ? 33 ILE A CG2 1 ATOM 245 C CG2 B ILE A 1 33 ? -23.470 -27.347 8.622 0.41 25.91 ? 33 ILE A CG2 1 ATOM 246 C CD1 A ILE A 1 33 ? -21.587 -30.263 10.247 0.59 25.06 ? 33 ILE A CD1 1 ATOM 247 C CD1 B ILE A 1 33 ? -21.781 -28.056 10.963 0.41 26.78 ? 33 ILE A CD1 1 ATOM 248 N N . HIS A 1 34 ? -25.952 -29.988 10.279 1.00 28.61 ? 34 HIS A N 1 ATOM 249 C CA . HIS A 1 34 ? -27.181 -29.716 11.022 1.00 24.39 ? 34 HIS A CA 1 ATOM 250 C C . HIS A 1 34 ? -26.812 -29.387 12.460 1.00 24.17 ? 34 HIS A C 1 ATOM 251 O O . HIS A 1 34 ? -25.779 -29.837 12.958 1.00 27.77 ? 34 HIS A O 1 ATOM 252 C CB . HIS A 1 34 ? -28.110 -30.933 10.998 1.00 25.78 ? 34 HIS A CB 1 ATOM 253 C CG . HIS A 1 34 ? -28.390 -31.461 9.627 1.00 26.38 ? 34 HIS A CG 1 ATOM 254 N ND1 . HIS A 1 34 ? -28.623 -30.636 8.544 1.00 20.38 ? 34 HIS A ND1 1 ATOM 255 C CD2 . HIS A 1 34 ? -28.467 -32.727 9.152 1.00 24.22 ? 34 HIS A CD2 1 ATOM 256 C CE1 . HIS A 1 34 ? -28.838 -31.375 7.469 1.00 22.76 ? 34 HIS A CE1 1 ATOM 257 N NE2 . HIS A 1 34 ? -28.751 -32.647 7.815 1.00 20.26 ? 34 HIS A NE2 1 ATOM 258 N N . TRP A 1 35 ? -27.649 -28.606 13.132 1.00 17.60 ? 35 TRP A N 1 ATOM 259 C CA . TRP A 1 35 ? -27.367 -28.240 14.515 1.00 19.64 ? 35 TRP A CA 1 ATOM 260 C C . TRP A 1 35 ? -28.500 -28.654 15.449 1.00 23.74 ? 35 TRP A C 1 ATOM 261 O O . TRP A 1 35 ? -29.666 -28.595 15.075 1.00 25.92 ? 35 TRP A O 1 ATOM 262 C CB . TRP A 1 35 ? -27.155 -26.734 14.649 1.00 21.24 ? 35 TRP A CB 1 ATOM 263 C CG . TRP A 1 35 ? -25.938 -26.188 13.993 1.00 21.74 ? 35 TRP A CG 1 ATOM 264 C CD1 . TRP A 1 35 ? -25.829 -25.744 12.706 1.00 21.44 ? 35 TRP A CD1 1 ATOM 265 C CD2 . TRP A 1 35 ? -24.655 -25.993 14.598 1.00 23.57 ? 35 TRP A CD2 1 ATOM 266 N NE1 . TRP A 1 35 ? -24.548 -25.295 12.469 1.00 24.43 ? 35 TRP A NE1 1 ATOM 267 C CE2 . TRP A 1 35 ? -23.807 -25.436 13.612 1.00 25.14 ? 35 TRP A CE2 1 ATOM 268 C CE3 . TRP A 1 35 ? -24.137 -26.244 15.871 1.00 21.91 ? 35 TRP A CE3 1 ATOM 269 C CZ2 . TRP A 1 35 ? -22.472 -25.120 13.865 1.00 21.97 ? 35 TRP A CZ2 1 ATOM 270 C CZ3 . TRP A 1 35 ? -22.810 -25.930 16.123 1.00 27.02 ? 35 TRP A CZ3 1 ATOM 271 C CH2 . TRP A 1 35 ? -21.992 -25.375 15.119 1.00 26.79 ? 35 TRP A CH2 1 ATOM 272 N N . TYR A 1 36 ? -28.141 -29.027 16.674 1.00 20.38 ? 36 TYR A N 1 ATOM 273 C CA . TYR A 1 36 ? -29.098 -29.442 17.692 1.00 17.00 ? 36 TYR A CA 1 ATOM 274 C C . TYR A 1 36 ? -28.898 -28.758 19.055 1.00 20.99 ? 36 TYR A C 1 ATOM 275 O O . TYR A 1 36 ? -27.786 -28.400 19.435 1.00 18.83 ? 36 TYR A O 1 ATOM 276 C CB . TYR A 1 36 ? -29.028 -30.953 17.883 1.00 19.45 ? 36 TYR A CB 1 ATOM 277 C CG . TYR A 1 36 ? -29.353 -31.763 16.655 1.00 17.23 ? 36 TYR A CG 1 ATOM 278 C CD1 . TYR A 1 36 ? -28.376 -32.058 15.725 1.00 20.90 ? 36 TYR A CD1 1 ATOM 279 C CD2 . TYR A 1 36 ? -30.633 -32.239 16.429 1.00 16.61 ? 36 TYR A CD2 1 ATOM 280 C CE1 . TYR A 1 36 ? -28.656 -32.809 14.602 1.00 22.42 ? 36 TYR A CE1 1 ATOM 281 C CE2 . TYR A 1 36 ? -30.925 -32.991 15.303 1.00 22.66 ? 36 TYR A CE2 1 ATOM 282 C CZ . TYR A 1 36 ? -29.926 -33.268 14.392 1.00 19.05 ? 36 TYR A CZ 1 ATOM 283 O OH . TYR A 1 36 ? -30.183 -34.012 13.273 1.00 24.02 ? 36 TYR A OH 1 ATOM 284 N N . GLN A 1 37 ? -29.988 -28.597 19.798 1.00 22.73 ? 37 GLN A N 1 ATOM 285 C CA . GLN A 1 37 ? -29.914 -28.081 21.157 1.00 14.64 ? 37 GLN A CA 1 ATOM 286 C C . GLN A 1 37 ? -30.197 -29.215 22.143 1.00 21.57 ? 37 GLN A C 1 ATOM 287 O O . GLN A 1 37 ? -31.114 -30.004 21.925 1.00 21.32 ? 37 GLN A O 1 ATOM 288 C CB . GLN A 1 37 ? -30.951 -26.970 21.348 1.00 19.50 ? 37 GLN A CB 1 ATOM 289 C CG . GLN A 1 37 ? -31.030 -26.437 22.774 1.00 22.65 ? 37 GLN A CG 1 ATOM 290 C CD . GLN A 1 37 ? -32.138 -25.423 22.959 1.00 25.31 ? 37 GLN A CD 1 ATOM 291 O OE1 . GLN A 1 37 ? -33.320 -25.755 22.835 1.00 21.20 ? 37 GLN A OE1 1 ATOM 292 N NE2 . GLN A 1 37 ? -31.762 -24.170 23.254 1.00 21.70 ? 37 GLN A NE2 1 ATOM 293 N N . GLN A 1 38 ? -29.419 -29.326 23.217 1.00 16.09 ? 38 GLN A N 1 ATOM 294 C CA . GLN A 1 38 ? -29.822 -30.242 24.271 1.00 19.80 ? 38 GLN A CA 1 ATOM 295 C C . GLN A 1 38 ? -29.998 -29.560 25.630 1.00 22.29 ? 38 GLN A C 1 ATOM 296 O O . GLN A 1 38 ? -29.030 -29.214 26.295 1.00 22.32 ? 38 GLN A O 1 ATOM 297 C CB . GLN A 1 38 ? -28.895 -31.452 24.386 1.00 25.70 ? 38 GLN A CB 1 ATOM 298 C CG . GLN A 1 38 ? -29.502 -32.546 25.295 1.00 22.13 ? 38 GLN A CG 1 ATOM 299 C CD . GLN A 1 38 ? -28.788 -33.872 25.171 1.00 19.20 ? 38 GLN A CD 1 ATOM 300 O OE1 . GLN A 1 38 ? -27.581 -33.917 24.936 1.00 23.96 ? 38 GLN A OE1 1 ATOM 301 N NE2 . GLN A 1 38 ? -29.527 -34.958 25.316 1.00 14.51 ? 38 GLN A NE2 1 ATOM 302 N N . ARG A 1 39 ? -31.245 -29.367 26.037 1.00 18.77 ? 39 ARG A N 1 ATOM 303 C CA . ARG A 1 39 ? -31.500 -28.800 27.348 1.00 25.22 ? 39 ARG A CA 1 ATOM 304 C C . ARG A 1 39 ? -31.417 -29.877 28.427 1.00 22.73 ? 39 ARG A C 1 ATOM 305 O O . ARG A 1 39 ? -31.398 -31.067 28.122 1.00 20.25 ? 39 ARG A O 1 ATOM 306 C CB . ARG A 1 39 ? -32.862 -28.135 27.373 1.00 26.14 ? 39 ARG A CB 1 ATOM 307 C CG . ARG A 1 39 ? -32.890 -26.766 26.765 1.00 29.40 ? 39 ARG A CG 1 ATOM 308 C CD . ARG A 1 39 ? -34.311 -26.291 26.695 1.00 26.55 ? 39 ARG A CD 1 ATOM 309 N NE . ARG A 1 39 ? -34.465 -25.123 25.847 1.00 26.54 ? 39 ARG A NE 1 ATOM 310 C CZ . ARG A 1 39 ? -35.642 -24.663 25.444 1.00 46.59 ? 39 ARG A CZ 1 ATOM 311 N NH1 . ARG A 1 39 ? -36.753 -25.288 25.813 1.00 33.86 ? 39 ARG A NH1 1 ATOM 312 N NH2 . ARG A 1 39 ? -35.704 -23.586 24.670 1.00 48.45 ? 39 ARG A NH2 1 ATOM 313 N N . THR A 1 40 ? -31.360 -29.448 29.681 1.00 21.21 ? 40 THR A N 1 ATOM 314 C CA . THR A 1 40 ? -31.273 -30.373 30.808 1.00 24.16 ? 40 THR A CA 1 ATOM 315 C C . THR A 1 40 ? -32.428 -31.366 30.793 1.00 23.55 ? 40 THR A C 1 ATOM 316 O O . THR A 1 40 ? -33.590 -30.968 30.730 1.00 19.95 ? 40 THR A O 1 ATOM 317 C CB . THR A 1 40 ? -31.243 -29.616 32.146 1.00 19.49 ? 40 THR A CB 1 ATOM 318 O OG1 . THR A 1 40 ? -30.054 -28.821 32.202 1.00 18.67 ? 40 THR A OG1 1 ATOM 319 C CG2 . THR A 1 40 ? -31.268 -30.586 33.319 1.00 16.04 ? 40 THR A CG2 1 ATOM 320 N N . ASN A 1 41 ? -32.081 -32.654 30.809 1.00 23.48 ? 41 ASN A N 1 ATOM 321 C CA . ASN A 1 41 ? -33.044 -33.766 30.705 1.00 27.17 ? 41 ASN A CA 1 ATOM 322 C C . ASN A 1 41 ? -33.774 -33.975 29.376 1.00 27.53 ? 41 ASN A C 1 ATOM 323 O O . ASN A 1 41 ? -34.661 -34.823 29.288 1.00 26.77 ? 41 ASN A O 1 ATOM 324 C CB . ASN A 1 41 ? -34.050 -33.732 31.854 1.00 22.71 ? 41 ASN A CB 1 ATOM 325 C CG . ASN A 1 41 ? -33.414 -34.109 33.165 1.00 30.06 ? 41 ASN A CG 1 ATOM 326 O OD1 . ASN A 1 41 ? -33.618 -33.455 34.192 1.00 24.72 ? 41 ASN A OD1 1 ATOM 327 N ND2 . ASN A 1 41 ? -32.601 -35.161 33.128 1.00 22.78 ? 41 ASN A ND2 1 ATOM 328 N N . GLY A 1 42 ? -33.397 -33.227 28.344 1.00 18.29 ? 42 GLY A N 1 ATOM 329 C CA . GLY A 1 42 ? -34.104 -33.315 27.076 1.00 23.41 ? 42 GLY A CA 1 ATOM 330 C C . GLY A 1 42 ? -33.473 -34.247 26.060 1.00 21.67 ? 42 GLY A C 1 ATOM 331 O O . GLY A 1 42 ? -32.379 -34.772 26.259 1.00 22.42 ? 42 GLY A O 1 ATOM 332 N N . SER A 1 43 ? -34.186 -34.473 24.967 1.00 22.41 ? 43 SER A N 1 ATOM 333 C CA . SER A 1 43 ? -33.591 -35.101 23.797 1.00 16.91 ? 43 SER A CA 1 ATOM 334 C C . SER A 1 43 ? -33.189 -33.936 22.916 1.00 18.21 ? 43 SER A C 1 ATOM 335 O O . SER A 1 43 ? -33.711 -32.834 23.100 1.00 17.91 ? 43 SER A O 1 ATOM 336 C CB . SER A 1 43 ? -34.617 -35.969 23.080 1.00 16.62 ? 43 SER A CB 1 ATOM 337 O OG . SER A 1 43 ? -35.338 -36.762 23.994 1.00 24.63 ? 43 SER A OG 1 ATOM 338 N N . PRO A 1 44 ? -32.259 -34.157 21.966 1.00 19.01 ? 44 PRO A N 1 ATOM 339 C CA . PRO A 1 44 ? -31.864 -33.064 21.064 1.00 18.10 ? 44 PRO A CA 1 ATOM 340 C C . PRO A 1 44 ? -33.056 -32.467 20.306 1.00 17.30 ? 44 PRO A C 1 ATOM 341 O O . PRO A 1 44 ? -33.996 -33.177 19.942 1.00 17.81 ? 44 PRO A O 1 ATOM 342 C CB . PRO A 1 44 ? -30.902 -33.737 20.080 1.00 17.70 ? 44 PRO A CB 1 ATOM 343 C CG . PRO A 1 44 ? -30.400 -34.970 20.789 1.00 16.97 ? 44 PRO A CG 1 ATOM 344 C CD . PRO A 1 44 ? -31.524 -35.408 21.690 1.00 19.66 ? 44 PRO A CD 1 ATOM 345 N N . ARG A 1 45 ? -32.999 -31.155 20.113 1.00 14.64 ? 45 ARG A N 1 ATOM 346 C CA . ARG A 1 45 ? -33.974 -30.392 19.347 1.00 18.42 ? 45 ARG A CA 1 ATOM 347 C C . ARG A 1 45 ? -33.224 -29.824 18.124 1.00 21.71 ? 45 ARG A C 1 ATOM 348 O O . ARG A 1 45 ? -32.185 -29.176 18.267 1.00 21.94 ? 45 ARG A O 1 ATOM 349 C CB . ARG A 1 45 ? -34.555 -29.283 20.246 1.00 20.00 ? 45 ARG A CB 1 ATOM 350 C CG . ARG A 1 45 ? -35.458 -28.199 19.618 1.00 26.52 ? 45 ARG A CG 1 ATOM 351 C CD . ARG A 1 45 ? -35.444 -26.936 20.538 1.00 30.83 ? 45 ARG A CD 1 ATOM 352 N NE . ARG A 1 45 ? -36.397 -25.860 20.216 1.00 32.29 ? 45 ARG A NE 1 ATOM 353 C CZ . ARG A 1 45 ? -36.478 -24.686 20.858 1.00 35.09 ? 45 ARG A CZ 1 ATOM 354 N NH1 . ARG A 1 45 ? -35.677 -24.406 21.871 1.00 27.69 ? 45 ARG A NH1 1 ATOM 355 N NH2 . ARG A 1 45 ? -37.369 -23.775 20.486 1.00 40.64 ? 45 ARG A NH2 1 ATOM 356 N N . LEU A 1 46 ? -33.728 -30.119 16.929 1.00 21.91 ? 46 LEU A N 1 ATOM 357 C CA . LEU A 1 46 ? -33.154 -29.627 15.670 1.00 18.53 ? 46 LEU A CA 1 ATOM 358 C C . LEU A 1 46 ? -33.305 -28.111 15.495 1.00 19.54 ? 46 LEU A C 1 ATOM 359 O O . LEU A 1 46 ? -34.414 -27.601 15.460 1.00 24.49 ? 46 LEU A O 1 ATOM 360 C CB . LEU A 1 46 ? -33.822 -30.347 14.489 1.00 17.62 ? 46 LEU A CB 1 ATOM 361 C CG . LEU A 1 46 ? -33.439 -29.892 13.088 1.00 19.90 ? 46 LEU A CG 1 ATOM 362 C CD1 . LEU A 1 46 ? -31.968 -30.230 12.812 1.00 23.30 ? 46 LEU A CD1 1 ATOM 363 C CD2 . LEU A 1 46 ? -34.342 -30.516 12.070 1.00 17.10 ? 46 LEU A CD2 1 ATOM 364 N N . LEU A 1 47 ? -32.197 -27.390 15.364 1.00 21.69 ? 47 LEU A N 1 ATOM 365 C CA . LEU A 1 47 ? -32.253 -25.932 15.244 1.00 19.31 ? 47 LEU A CA 1 ATOM 366 C C . LEU A 1 47 ? -32.064 -25.438 13.808 1.00 33.13 ? 47 LEU A C 1 ATOM 367 O O . LEU A 1 47 ? -32.757 -24.525 13.342 1.00 35.94 ? 47 LEU A O 1 ATOM 368 C CB . LEU A 1 47 ? -31.162 -25.304 16.106 1.00 22.27 ? 47 LEU A CB 1 ATOM 369 C CG . LEU A 1 47 ? -31.197 -25.549 17.616 1.00 17.44 ? 47 LEU A CG 1 ATOM 370 C CD1 . LEU A 1 47 ? -29.847 -25.186 18.238 1.00 13.26 ? 47 LEU A CD1 1 ATOM 371 C CD2 . LEU A 1 47 ? -32.338 -24.757 18.242 1.00 12.94 ? 47 LEU A CD2 1 ATOM 372 N N . ILE A 1 48 ? -31.090 -26.020 13.120 1.00 29.20 ? 48 ILE A N 1 ATOM 373 C CA . ILE A 1 48 ? -30.743 -25.584 11.778 1.00 28.32 ? 48 ILE A CA 1 ATOM 374 C C . ILE A 1 48 ? -30.421 -26.805 10.926 1.00 27.72 ? 48 ILE A C 1 ATOM 375 O O . ILE A 1 48 ? -29.713 -27.710 11.370 1.00 27.52 ? 48 ILE A O 1 ATOM 376 C CB . ILE A 1 48 ? -29.494 -24.658 11.782 1.00 23.60 ? 48 ILE A CB 1 ATOM 377 C CG1 . ILE A 1 48 ? -29.714 -23.412 12.636 1.00 22.98 ? 48 ILE A CG1 1 ATOM 378 C CG2 . ILE A 1 48 ? -29.110 -24.261 10.361 1.00 20.02 ? 48 ILE A CG2 1 ATOM 379 C CD1 . ILE A 1 48 ? -30.710 -22.454 12.072 1.00 25.63 ? 48 ILE A CD1 1 ATOM 380 N N . LYS A 1 49 ? -30.908 -26.850 9.717 1.00 21.71 ? 49 LYS A N 1 ATOM 381 C CA . LYS A 1 49 ? -30.484 -27.860 8.783 1.00 23.83 ? 49 LYS A CA 1 ATOM 382 C C . LYS A 1 49 ? -29.703 -27.269 7.626 1.00 26.98 ? 49 LYS A C 1 ATOM 383 O O . LYS A 1 49 ? -29.949 -26.188 7.222 1.00 25.94 ? 49 LYS A O 1 ATOM 384 C CB . LYS A 1 49 ? -31.681 -28.648 8.279 1.00 23.12 ? 49 LYS A CB 1 ATOM 385 C CG . LYS A 1 49 ? -32.566 -27.857 7.378 1.00 21.84 ? 49 LYS A CG 1 ATOM 386 C CD . LYS A 1 49 ? -33.722 -28.665 6.892 1.00 32.53 ? 49 LYS A CD 1 ATOM 387 C CE . LYS A 1 49 ? -34.891 -27.762 6.674 1.00 22.23 ? 49 LYS A CE 1 ATOM 388 N NZ . LYS A 1 49 ? -35.412 -27.888 5.328 1.00 28.12 ? 49 LYS A NZ 1 ATOM 389 N N . TYR A 1 50 ? -28.755 -28.026 7.111 1.00 24.96 ? 50 TYR A N 1 ATOM 390 C CA . TYR A 1 50 ? -27.967 -27.633 5.946 1.00 24.17 ? 50 TYR A CA 1 ATOM 391 C C . TYR A 1 50 ? -27.328 -26.259 6.127 1.00 26.98 ? 50 TYR A C 1 ATOM 392 O O . TYR A 1 50 ? -27.529 -25.351 5.321 1.00 29.81 ? 50 TYR A O 1 ATOM 393 C CB . TYR A 1 50 ? -28.806 -27.723 4.670 1.00 21.08 ? 50 TYR A CB 1 ATOM 394 C CG . TYR A 1 50 ? -29.187 -29.148 4.335 1.00 25.13 ? 50 TYR A CG 1 ATOM 395 C CD1 . TYR A 1 50 ? -30.452 -29.650 4.656 1.00 22.23 ? 50 TYR A CD1 1 ATOM 396 C CD2 . TYR A 1 50 ? -28.273 -30.007 3.719 1.00 18.98 ? 50 TYR A CD2 1 ATOM 397 C CE1 . TYR A 1 50 ? -30.805 -30.962 4.351 1.00 18.00 ? 50 TYR A CE1 1 ATOM 398 C CE2 . TYR A 1 50 ? -28.611 -31.324 3.423 1.00 11.92 ? 50 TYR A CE2 1 ATOM 399 C CZ . TYR A 1 50 ? -29.876 -31.792 3.744 1.00 20.12 ? 50 TYR A CZ 1 ATOM 400 O OH . TYR A 1 50 ? -30.217 -33.095 3.451 1.00 26.62 ? 50 TYR A OH 1 ATOM 401 N N . ALA A 1 51 ? -26.586 -26.128 7.223 1.00 21.66 ? 51 ALA A N 1 ATOM 402 C CA . ALA A 1 51 ? -25.807 -24.929 7.538 1.00 27.55 ? 51 ALA A CA 1 ATOM 403 C C . ALA A 1 51 ? -26.596 -23.689 7.917 1.00 26.96 ? 51 ALA A C 1 ATOM 404 O O . ALA A 1 51 ? -26.261 -23.031 8.904 1.00 19.65 ? 51 ALA A O 1 ATOM 405 C CB . ALA A 1 51 ? -24.796 -24.611 6.435 1.00 27.10 ? 51 ALA A CB 1 ATOM 406 N N . SER A 1 52 ? -27.646 -23.382 7.157 1.00 24.33 ? 52 SER A N 1 ATOM 407 C CA . SER A 1 52 ? -28.287 -22.074 7.282 1.00 26.32 ? 52 SER A CA 1 ATOM 408 C C . SER A 1 52 ? -29.806 -22.051 7.257 1.00 18.77 ? 52 SER A C 1 ATOM 409 O O . SER A 1 52 ? -30.405 -21.032 7.566 1.00 21.08 ? 52 SER A O 1 ATOM 410 C CB . SER A 1 52 ? -27.753 -21.121 6.203 1.00 29.14 ? 52 SER A CB 1 ATOM 411 O OG . SER A 1 52 ? -27.817 -21.715 4.905 1.00 38.42 ? 52 SER A OG 1 ATOM 412 N N . GLU A 1 53 ? -30.427 -23.163 6.892 1.00 22.83 ? 53 GLU A N 1 ATOM 413 C CA . GLU A 1 53 ? -31.872 -23.194 6.671 1.00 16.93 ? 53 GLU A CA 1 ATOM 414 C C . GLU A 1 53 ? -32.695 -23.246 7.946 1.00 28.26 ? 53 GLU A C 1 ATOM 415 O O . GLU A 1 53 ? -32.360 -23.963 8.897 1.00 33.03 ? 53 GLU A O 1 ATOM 416 C CB . GLU A 1 53 ? -32.243 -24.374 5.790 1.00 20.06 ? 53 GLU A CB 1 ATOM 417 C CG . GLU A 1 53 ? -31.532 -24.353 4.463 1.00 28.86 ? 53 GLU A CG 1 ATOM 418 C CD . GLU A 1 53 ? -31.870 -25.548 3.611 1.00 35.22 ? 53 GLU A CD 1 ATOM 419 O OE1 . GLU A 1 53 ? -32.663 -26.401 4.082 1.00 34.27 ? 53 GLU A OE1 1 ATOM 420 O OE2 . GLU A 1 53 ? -31.336 -25.630 2.477 1.00 32.08 ? 53 GLU A OE2 1 ATOM 421 N N . SER A 1 54 ? -33.786 -22.489 7.956 1.00 26.13 ? 54 SER A N 1 ATOM 422 C CA . SER A 1 54 ? -34.643 -22.416 9.121 1.00 26.99 ? 54 SER A CA 1 ATOM 423 C C . SER A 1 54 ? -35.411 -23.700 9.371 1.00 36.38 ? 54 SER A C 1 ATOM 424 O O . SER A 1 54 ? -35.685 -24.470 8.443 1.00 30.12 ? 54 SER A O 1 ATOM 425 C CB . SER A 1 54 ? -35.614 -21.248 8.996 1.00 30.84 ? 54 SER A CB 1 ATOM 426 O OG . SER A 1 54 ? -35.023 -20.062 9.497 1.00 52.30 ? 54 SER A OG 1 ATOM 427 N N . ILE A 1 55 ? -35.746 -23.914 10.641 1.00 33.91 ? 55 ILE A N 1 ATOM 428 C CA . ILE A 1 55 ? -36.609 -25.005 11.061 1.00 27.38 ? 55 ILE A CA 1 ATOM 429 C C . ILE A 1 55 ? -37.821 -24.353 11.691 1.00 27.14 ? 55 ILE A C 1 ATOM 430 O O . ILE A 1 55 ? -37.695 -23.355 12.401 1.00 31.23 ? 55 ILE A O 1 ATOM 431 C CB . ILE A 1 55 ? -35.907 -25.900 12.099 1.00 31.05 ? 55 ILE A CB 1 ATOM 432 C CG1 . ILE A 1 55 ? -34.588 -26.404 11.537 1.00 23.87 ? 55 ILE A CG1 1 ATOM 433 C CG2 . ILE A 1 55 ? -36.797 -27.071 12.498 1.00 26.59 ? 55 ILE A CG2 1 ATOM 434 C CD1 . ILE A 1 55 ? -34.772 -27.294 10.350 1.00 24.18 ? 55 ILE A CD1 1 ATOM 435 N N . SER A 1 56 ? -39.003 -24.883 11.420 1.00 35.33 ? 56 SER A N 1 ATOM 436 C CA . SER A 1 56 ? -40.214 -24.230 11.886 1.00 32.82 ? 56 SER A CA 1 ATOM 437 C C . SER A 1 56 ? -40.353 -24.418 13.392 1.00 40.14 ? 56 SER A C 1 ATOM 438 O O . SER A 1 56 ? -40.102 -25.508 13.913 1.00 36.35 ? 56 SER A O 1 ATOM 439 C CB . SER A 1 56 ? -41.427 -24.815 11.184 1.00 36.33 ? 56 SER A CB 1 ATOM 440 O OG . SER A 1 56 ? -41.827 -26.004 11.841 1.00 47.63 ? 56 SER A OG 1 ATOM 441 N N . GLY A 1 57 ? -40.744 -23.355 14.089 1.00 33.09 ? 57 GLY A N 1 ATOM 442 C CA . GLY A 1 57 ? -40.918 -23.408 15.529 1.00 31.02 ? 57 GLY A CA 1 ATOM 443 C C . GLY A 1 57 ? -39.712 -22.918 16.309 1.00 33.51 ? 57 GLY A C 1 ATOM 444 O O . GLY A 1 57 ? -39.783 -22.714 17.518 1.00 38.50 ? 57 GLY A O 1 ATOM 445 N N . ILE A 1 58 ? -38.598 -22.736 15.611 1.00 39.65 ? 58 ILE A N 1 ATOM 446 C CA . ILE A 1 58 ? -37.355 -22.286 16.221 1.00 27.65 ? 58 ILE A CA 1 ATOM 447 C C . ILE A 1 58 ? -37.271 -20.772 16.129 1.00 24.70 ? 58 ILE A C 1 ATOM 448 O O . ILE A 1 58 ? -37.395 -20.215 15.045 1.00 38.16 ? 58 ILE A O 1 ATOM 449 C CB . ILE A 1 58 ? -36.138 -22.927 15.499 1.00 26.98 ? 58 ILE A CB 1 ATOM 450 C CG1 . ILE A 1 58 ? -36.197 -24.458 15.601 1.00 25.75 ? 58 ILE A CG1 1 ATOM 451 C CG2 . ILE A 1 58 ? -34.811 -22.395 16.045 1.00 23.43 ? 58 ILE A CG2 1 ATOM 452 C CD1 . ILE A 1 58 ? -36.284 -24.976 17.021 1.00 22.69 ? 58 ILE A CD1 1 ATOM 453 N N . PRO A 1 59 ? -37.056 -20.099 17.265 1.00 22.13 ? 59 PRO A N 1 ATOM 454 C CA . PRO A 1 59 ? -36.929 -18.637 17.326 1.00 26.17 ? 59 PRO A CA 1 ATOM 455 C C . PRO A 1 59 ? -35.945 -18.086 16.290 1.00 30.26 ? 59 PRO A C 1 ATOM 456 O O . PRO A 1 59 ? -34.949 -18.732 15.986 1.00 28.32 ? 59 PRO A O 1 ATOM 457 C CB . PRO A 1 59 ? -36.368 -18.394 18.728 1.00 26.21 ? 59 PRO A CB 1 ATOM 458 C CG . PRO A 1 59 ? -36.845 -19.563 19.526 1.00 40.07 ? 59 PRO A CG 1 ATOM 459 C CD . PRO A 1 59 ? -36.849 -20.734 18.578 1.00 34.05 ? 59 PRO A CD 1 ATOM 460 N N . SER A 1 60 ? -36.212 -16.889 15.782 1.00 29.19 ? 60 SER A N 1 ATOM 461 C CA . SER A 1 60 ? -35.380 -16.299 14.740 1.00 35.04 ? 60 SER A CA 1 ATOM 462 C C . SER A 1 60 ? -33.972 -15.943 15.223 1.00 36.07 ? 60 SER A C 1 ATOM 463 O O . SER A 1 60 ? -33.080 -15.669 14.409 1.00 31.10 ? 60 SER A O 1 ATOM 464 C CB . SER A 1 60 ? -36.055 -15.051 14.176 1.00 31.30 ? 60 SER A CB 1 ATOM 465 O OG . SER A 1 60 ? -36.053 -14.024 15.154 1.00 37.75 ? 60 SER A OG 1 ATOM 466 N N . ARG A 1 61 ? -33.764 -15.936 16.538 1.00 33.30 ? 61 ARG A N 1 ATOM 467 C CA . ARG A 1 61 ? -32.457 -15.564 17.064 1.00 24.81 ? 61 ARG A CA 1 ATOM 468 C C . ARG A 1 61 ? -31.414 -16.627 16.717 1.00 33.03 ? 61 ARG A C 1 ATOM 469 O O . ARG A 1 61 ? -30.209 -16.371 16.782 1.00 23.40 ? 61 ARG A O 1 ATOM 470 C CB . ARG A 1 61 ? -32.513 -15.295 18.570 1.00 28.19 ? 61 ARG A CB 1 ATOM 471 C CG . ARG A 1 61 ? -32.714 -16.512 19.464 1.00 28.01 ? 61 ARG A CG 1 ATOM 472 C CD . ARG A 1 61 ? -32.777 -16.067 20.931 1.00 35.26 ? 61 ARG A CD 1 ATOM 473 N NE . ARG A 1 61 ? -33.112 -17.166 21.820 1.00 23.22 ? 61 ARG A NE 1 ATOM 474 C CZ . ARG A 1 61 ? -34.353 -17.489 22.156 1.00 36.41 ? 61 ARG A CZ 1 ATOM 475 N NH1 . ARG A 1 61 ? -35.367 -16.776 21.685 1.00 37.77 ? 61 ARG A NH1 1 ATOM 476 N NH2 . ARG A 1 61 ? -34.579 -18.519 22.962 1.00 34.29 ? 61 ARG A NH2 1 ATOM 477 N N . PHE A 1 62 ? -31.887 -17.813 16.338 1.00 21.28 ? 62 PHE A N 1 ATOM 478 C CA . PHE A 1 62 ? -31.005 -18.892 15.925 1.00 23.77 ? 62 PHE A CA 1 ATOM 479 C C . PHE A 1 62 ? -30.760 -18.855 14.426 1.00 27.07 ? 62 PHE A C 1 ATOM 480 O O . PHE A 1 62 ? -31.703 -18.943 13.639 1.00 34.04 ? 62 PHE A O 1 ATOM 481 C CB . PHE A 1 62 ? -31.608 -20.249 16.294 1.00 25.63 ? 62 PHE A CB 1 ATOM 482 C CG . PHE A 1 62 ? -31.668 -20.506 17.773 1.00 20.97 ? 62 PHE A CG 1 ATOM 483 C CD1 . PHE A 1 62 ? -32.809 -20.202 18.500 1.00 26.15 ? 62 PHE A CD1 1 ATOM 484 C CD2 . PHE A 1 62 ? -30.591 -21.065 18.431 1.00 20.77 ? 62 PHE A CD2 1 ATOM 485 C CE1 . PHE A 1 62 ? -32.874 -20.428 19.875 1.00 26.54 ? 62 PHE A CE1 1 ATOM 486 C CE2 . PHE A 1 62 ? -30.640 -21.303 19.808 1.00 31.27 ? 62 PHE A CE2 1 ATOM 487 C CZ . PHE A 1 62 ? -31.792 -20.979 20.533 1.00 23.46 ? 62 PHE A CZ 1 ATOM 488 N N . SER A 1 63 ? -29.495 -18.734 14.034 1.00 24.07 ? 63 SER A N 1 ATOM 489 C CA . SER A 1 63 ? -29.093 -18.867 12.629 1.00 27.64 ? 63 SER A CA 1 ATOM 490 C C . SER A 1 63 ? -27.742 -19.583 12.518 1.00 31.43 ? 63 SER A C 1 ATOM 491 O O . SER A 1 63 ? -27.012 -19.717 13.510 1.00 27.41 ? 63 SER A O 1 ATOM 492 C CB . SER A 1 63 ? -29.017 -17.501 11.944 1.00 21.64 ? 63 SER A CB 1 ATOM 493 O OG . SER A 1 63 ? -28.005 -16.699 12.527 1.00 33.38 ? 63 SER A OG 1 ATOM 494 N N . GLY A 1 64 ? -27.415 -20.048 11.316 1.00 25.69 ? 64 GLY A N 1 ATOM 495 C CA . GLY A 1 64 ? -26.134 -20.682 11.081 1.00 18.31 ? 64 GLY A CA 1 ATOM 496 C C . GLY A 1 64 ? -25.549 -20.349 9.726 1.00 22.55 ? 64 GLY A C 1 ATOM 497 O O . GLY A 1 64 ? -26.272 -20.023 8.785 1.00 23.51 ? 64 GLY A O 1 ATOM 498 N N . SER A 1 65 ? -24.229 -20.434 9.621 1.00 26.67 ? 65 SER A N 1 ATOM 499 C CA . SER A 1 65 ? -23.559 -20.162 8.360 1.00 25.29 ? 65 SER A CA 1 ATOM 500 C C . SER A 1 65 ? -22.339 -21.059 8.178 1.00 30.32 ? 65 SER A C 1 ATOM 501 O O . SER A 1 65 ? -21.989 -21.852 9.066 1.00 32.17 ? 65 SER A O 1 ATOM 502 C CB . SER A 1 65 ? -23.171 -18.684 8.264 1.00 23.80 ? 65 SER A CB 1 ATOM 503 O OG . SER A 1 65 ? -22.087 -18.395 9.128 1.00 37.99 ? 65 SER A OG 1 ATOM 504 N N . GLY A 1 66 ? -21.702 -20.929 7.020 1.00 24.61 ? 66 GLY A N 1 ATOM 505 C CA . GLY A 1 66 ? -20.523 -21.707 6.709 1.00 23.65 ? 66 GLY A CA 1 ATOM 506 C C . GLY A 1 66 ? -20.722 -22.685 5.562 1.00 30.69 ? 66 GLY A C 1 ATOM 507 O O . GLY A 1 66 ? -21.858 -23.000 5.167 1.00 20.21 ? 66 GLY A O 1 ATOM 508 N N . SER A 1 67 ? -19.587 -23.138 5.028 1.00 29.49 ? 67 SER A N 1 ATOM 509 C CA . SER A 1 67 ? -19.493 -24.195 4.020 1.00 31.13 ? 67 SER A CA 1 ATOM 510 C C . SER A 1 67 ? -18.036 -24.674 3.955 1.00 30.50 ? 67 SER A C 1 ATOM 511 O O . SER A 1 67 ? -17.126 -23.990 4.434 1.00 29.99 ? 67 SER A O 1 ATOM 512 C CB . SER A 1 67 ? -19.911 -23.704 2.643 1.00 29.62 ? 67 SER A CB 1 ATOM 513 O OG . SER A 1 67 ? -18.923 -22.835 2.133 1.00 46.13 ? 67 SER A OG 1 ATOM 514 N N . GLY A 1 68 ? -17.818 -25.851 3.378 1.00 21.66 ? 68 GLY A N 1 ATOM 515 C CA . GLY A 1 68 ? -16.497 -26.447 3.364 1.00 21.08 ? 68 GLY A CA 1 ATOM 516 C C . GLY A 1 68 ? -16.221 -27.176 4.664 1.00 28.76 ? 68 GLY A C 1 ATOM 517 O O . GLY A 1 68 ? -16.674 -28.301 4.858 1.00 29.99 ? 68 GLY A O 1 ATOM 518 N N . THR A 1 69 ? -15.475 -26.539 5.562 1.00 27.70 ? 69 THR A N 1 ATOM 519 C CA . THR A 1 69 ? -15.125 -27.177 6.825 1.00 31.03 ? 69 THR A CA 1 ATOM 520 C C . THR A 1 69 ? -15.344 -26.300 8.052 1.00 32.08 ? 69 THR A C 1 ATOM 521 O O . THR A 1 69 ? -15.224 -26.779 9.177 1.00 33.48 ? 69 THR A O 1 ATOM 522 C CB . THR A 1 69 ? -13.654 -27.630 6.843 1.00 26.49 ? 69 THR A CB 1 ATOM 523 O OG1 . THR A 1 69 ? -12.812 -26.492 6.661 1.00 27.07 ? 69 THR A OG1 1 ATOM 524 C CG2 . THR A 1 69 ? -13.382 -28.642 5.761 1.00 25.73 ? 69 THR A CG2 1 ATOM 525 N N . ASP A 1 70 ? -15.654 -25.026 7.843 1.00 27.01 ? 70 ASP A N 1 ATOM 526 C CA . ASP A 1 70 ? -15.747 -24.089 8.956 1.00 25.21 ? 70 ASP A CA 1 ATOM 527 C C . ASP A 1 70 ? -17.173 -23.535 9.091 1.00 32.71 ? 70 ASP A C 1 ATOM 528 O O . ASP A 1 70 ? -17.639 -22.764 8.238 1.00 31.94 ? 70 ASP A O 1 ATOM 529 C CB . ASP A 1 70 ? -14.725 -22.967 8.774 1.00 30.41 ? 70 ASP A CB 1 ATOM 530 C CG . ASP A 1 70 ? -14.579 -22.086 10.006 1.00 41.12 ? 70 ASP A CG 1 ATOM 531 O OD1 . ASP A 1 70 ? -15.090 -22.462 11.084 1.00 46.40 ? 70 ASP A OD1 1 ATOM 532 O OD2 . ASP A 1 70 ? -13.937 -21.011 9.895 1.00 40.18 ? 70 ASP A OD2 1 ATOM 533 N N . PHE A 1 71 ? -17.853 -23.938 10.170 1.00 24.87 ? 71 PHE A N 1 ATOM 534 C CA . PHE A 1 71 ? -19.271 -23.642 10.382 1.00 26.65 ? 71 PHE A CA 1 ATOM 535 C C . PHE A 1 71 ? -19.563 -22.877 11.667 1.00 30.03 ? 71 PHE A C 1 ATOM 536 O O . PHE A 1 71 ? -18.834 -22.988 12.664 1.00 24.21 ? 71 PHE A O 1 ATOM 537 C CB . PHE A 1 71 ? -20.079 -24.943 10.359 1.00 26.85 ? 71 PHE A CB 1 ATOM 538 C CG . PHE A 1 71 ? -19.955 -25.690 9.065 1.00 30.33 ? 71 PHE A CG 1 ATOM 539 C CD1 . PHE A 1 71 ? -20.708 -25.318 7.964 1.00 26.87 ? 71 PHE A CD1 1 ATOM 540 C CD2 . PHE A 1 71 ? -19.063 -26.738 8.940 1.00 23.64 ? 71 PHE A CD2 1 ATOM 541 C CE1 . PHE A 1 71 ? -20.584 -25.987 6.776 1.00 24.09 ? 71 PHE A CE1 1 ATOM 542 C CE2 . PHE A 1 71 ? -18.935 -27.408 7.753 1.00 27.59 ? 71 PHE A CE2 1 ATOM 543 C CZ . PHE A 1 71 ? -19.699 -27.033 6.666 1.00 26.14 ? 71 PHE A CZ 1 ATOM 544 N N . THR A 1 72 ? -20.647 -22.108 11.644 1.00 30.35 ? 72 THR A N 1 ATOM 545 C CA . THR A 1 72 ? -21.022 -21.302 12.802 1.00 24.89 ? 72 THR A CA 1 ATOM 546 C C . THR A 1 72 ? -22.515 -21.340 13.103 1.00 24.59 ? 72 THR A C 1 ATOM 547 O O . THR A 1 72 ? -23.335 -21.160 12.218 1.00 24.25 ? 72 THR A O 1 ATOM 548 C CB . THR A 1 72 ? -20.572 -19.831 12.646 1.00 23.01 ? 72 THR A CB 1 ATOM 549 O OG1 . THR A 1 72 ? -19.148 -19.783 12.474 1.00 16.77 ? 72 THR A OG1 1 ATOM 550 C CG2 . THR A 1 72 ? -20.971 -19.005 13.882 1.00 23.59 ? 72 THR A CG2 1 ATOM 551 N N . LEU A 1 73 ? -22.847 -21.587 14.368 1.00 27.63 ? 73 LEU A N 1 ATOM 552 C CA . LEU A 1 73 ? -24.211 -21.449 14.872 1.00 26.08 ? 73 LEU A CA 1 ATOM 553 C C . LEU A 1 73 ? -24.267 -20.165 15.682 1.00 23.13 ? 73 LEU A C 1 ATOM 554 O O . LEU A 1 73 ? -23.391 -19.902 16.497 1.00 25.06 ? 73 LEU A O 1 ATOM 555 C CB . LEU A 1 73 ? -24.592 -22.642 15.757 1.00 25.17 ? 73 LEU A CB 1 ATOM 556 C CG . LEU A 1 73 ? -25.942 -22.579 16.484 1.00 25.42 ? 73 LEU A CG 1 ATOM 557 C CD1 . LEU A 1 73 ? -27.122 -22.619 15.506 1.00 20.14 ? 73 LEU A CD1 1 ATOM 558 C CD2 . LEU A 1 73 ? -26.048 -23.704 17.503 1.00 23.88 ? 73 LEU A CD2 1 ATOM 559 N N . SER A 1 74 ? -25.285 -19.352 15.451 1.00 22.98 ? 74 SER A N 1 ATOM 560 C CA . SER A 1 74 ? -25.349 -18.067 16.121 1.00 22.56 ? 74 SER A CA 1 ATOM 561 C C . SER A 1 74 ? -26.670 -17.805 16.828 1.00 26.32 ? 74 SER A C 1 ATOM 562 O O . SER A 1 74 ? -27.741 -18.121 16.309 1.00 28.96 ? 74 SER A O 1 ATOM 563 C CB . SER A 1 74 ? -25.043 -16.940 15.140 1.00 29.51 ? 74 SER A CB 1 ATOM 564 O OG . SER A 1 74 ? -23.650 -16.883 14.886 1.00 32.87 ? 74 SER A OG 1 ATOM 565 N N . ILE A 1 75 ? -26.573 -17.246 18.028 1.00 25.11 ? 75 ILE A N 1 ATOM 566 C CA . ILE A 1 75 ? -27.734 -16.714 18.728 1.00 34.53 ? 75 ILE A CA 1 ATOM 567 C C . ILE A 1 75 ? -27.521 -15.213 18.902 1.00 32.19 ? 75 ILE A C 1 ATOM 568 O O . ILE A 1 75 ? -26.596 -14.794 19.611 1.00 35.74 ? 75 ILE A O 1 ATOM 569 C CB . ILE A 1 75 ? -27.933 -17.378 20.104 1.00 31.77 ? 75 ILE A CB 1 ATOM 570 C CG1 . ILE A 1 75 ? -27.814 -18.897 19.985 1.00 27.24 ? 75 ILE A CG1 1 ATOM 571 C CG2 . ILE A 1 75 ? -29.286 -16.978 20.690 1.00 26.38 ? 75 ILE A CG2 1 ATOM 572 C CD1 . ILE A 1 75 ? -27.925 -19.619 21.300 1.00 28.28 ? 75 ILE A CD1 1 ATOM 573 N N . ASN A 1 76 ? -28.353 -14.402 18.251 1.00 32.90 ? 76 ASN A N 1 ATOM 574 C CA . ASN A 1 76 ? -28.064 -12.966 18.182 1.00 45.05 ? 76 ASN A CA 1 ATOM 575 C C . ASN A 1 76 ? -28.302 -12.197 19.480 1.00 42.95 ? 76 ASN A C 1 ATOM 576 O O . ASN A 1 76 ? -27.703 -11.144 19.699 1.00 47.84 ? 76 ASN A O 1 ATOM 577 C CB . ASN A 1 76 ? -28.750 -12.285 16.990 1.00 39.67 ? 76 ASN A CB 1 ATOM 578 C CG . ASN A 1 76 ? -30.231 -12.511 16.964 1.00 52.47 ? 76 ASN A CG 1 ATOM 579 O OD1 . ASN A 1 76 ? -30.859 -12.683 18.009 1.00 50.50 ? 76 ASN A OD1 1 ATOM 580 N ND2 . ASN A 1 76 ? -30.812 -12.510 15.761 1.00 56.61 ? 76 ASN A ND2 1 ATOM 581 N N . SER A 1 77 ? -29.166 -12.730 20.335 1.00 36.22 ? 77 SER A N 1 ATOM 582 C CA . SER A 1 77 ? -29.395 -12.144 21.647 1.00 36.94 ? 77 SER A CA 1 ATOM 583 C C . SER A 1 77 ? -29.863 -13.239 22.599 1.00 42.04 ? 77 SER A C 1 ATOM 584 O O . SER A 1 77 ? -31.049 -13.573 22.660 1.00 43.30 ? 77 SER A O 1 ATOM 585 C CB . SER A 1 77 ? -30.423 -11.018 21.562 1.00 29.44 ? 77 SER A CB 1 ATOM 586 O OG . SER A 1 77 ? -30.309 -10.148 22.672 1.00 42.37 ? 77 SER A OG 1 ATOM 587 N N . VAL A 1 78 ? -28.913 -13.787 23.344 1.00 32.17 ? 78 VAL A N 1 ATOM 588 C CA A VAL A 1 78 ? -29.170 -14.961 24.163 0.46 35.21 ? 78 VAL A CA 1 ATOM 589 C CA B VAL A 1 78 ? -29.162 -14.959 24.177 0.54 35.21 ? 78 VAL A CA 1 ATOM 590 C C . VAL A 1 78 ? -30.166 -14.699 25.296 1.00 36.84 ? 78 VAL A C 1 ATOM 591 O O . VAL A 1 78 ? -30.093 -13.690 25.991 1.00 38.81 ? 78 VAL A O 1 ATOM 592 C CB A VAL A 1 78 ? -27.844 -15.544 24.723 0.46 35.49 ? 78 VAL A CB 1 ATOM 593 C CB B VAL A 1 78 ? -27.847 -15.490 24.777 0.54 35.56 ? 78 VAL A CB 1 ATOM 594 C CG1 A VAL A 1 78 ? -27.092 -14.486 25.512 0.46 33.46 ? 78 VAL A CG1 1 ATOM 595 C CG1 B VAL A 1 78 ? -28.103 -16.723 25.626 0.54 36.33 ? 78 VAL A CG1 1 ATOM 596 C CG2 A VAL A 1 78 ? -28.110 -16.772 25.575 0.46 36.41 ? 78 VAL A CG2 1 ATOM 597 C CG2 B VAL A 1 78 ? -26.871 -15.805 23.674 0.54 31.71 ? 78 VAL A CG2 1 ATOM 598 N N . GLU A 1 79 ? -31.111 -15.617 25.459 1.00 35.96 ? 79 GLU A N 1 ATOM 599 C CA . GLU A 1 79 ? -32.020 -15.587 26.591 1.00 33.63 ? 79 GLU A CA 1 ATOM 600 C C . GLU A 1 79 ? -31.614 -16.697 27.557 1.00 32.80 ? 79 GLU A C 1 ATOM 601 O O . GLU A 1 79 ? -30.855 -17.595 27.193 1.00 31.31 ? 79 GLU A O 1 ATOM 602 C CB . GLU A 1 79 ? -33.456 -15.787 26.122 1.00 33.18 ? 79 GLU A CB 1 ATOM 603 C CG . GLU A 1 79 ? -33.928 -14.725 25.156 1.00 39.68 ? 79 GLU A CG 1 ATOM 604 C CD . GLU A 1 79 ? -35.338 -14.976 24.669 1.00 57.98 ? 79 GLU A CD 1 ATOM 605 O OE1 . GLU A 1 79 ? -35.999 -15.888 25.215 1.00 54.61 ? 79 GLU A OE1 1 ATOM 606 O OE2 . GLU A 1 79 ? -35.784 -14.265 23.740 1.00 65.64 ? 79 GLU A OE2 1 ATOM 607 N N . SER A 1 80 ? -32.115 -16.644 28.785 1.00 29.37 ? 80 SER A N 1 ATOM 608 C CA . SER A 1 80 ? -31.754 -17.637 29.797 1.00 37.27 ? 80 SER A CA 1 ATOM 609 C C . SER A 1 80 ? -32.233 -19.032 29.388 1.00 29.75 ? 80 SER A C 1 ATOM 610 O O . SER A 1 80 ? -31.645 -20.045 29.768 1.00 31.62 ? 80 SER A O 1 ATOM 611 C CB . SER A 1 80 ? -32.285 -17.248 31.185 1.00 32.12 ? 80 SER A CB 1 ATOM 612 O OG . SER A 1 80 ? -33.706 -17.232 31.210 1.00 45.98 ? 80 SER A OG 1 ATOM 613 N N . GLU A 1 81 ? -33.285 -19.071 28.585 1.00 24.68 ? 81 GLU A N 1 ATOM 614 C CA . GLU A 1 81 ? -33.825 -20.324 28.077 1.00 31.63 ? 81 GLU A CA 1 ATOM 615 C C . GLU A 1 81 ? -32.809 -21.025 27.173 1.00 30.39 ? 81 GLU A C 1 ATOM 616 O O . GLU A 1 81 ? -32.906 -22.220 26.932 1.00 33.85 ? 81 GLU A O 1 ATOM 617 C CB . GLU A 1 81 ? -35.134 -20.068 27.306 1.00 39.37 ? 81 GLU A CB 1 ATOM 618 C CG . GLU A 1 81 ? -36.334 -19.603 28.162 1.00 46.20 ? 81 GLU A CG 1 ATOM 619 C CD . GLU A 1 81 ? -36.196 -18.176 28.724 1.00 52.84 ? 81 GLU A CD 1 ATOM 620 O OE1 . GLU A 1 81 ? -35.536 -17.321 28.080 1.00 41.82 ? 81 GLU A OE1 1 ATOM 621 O OE2 . GLU A 1 81 ? -36.756 -17.914 29.818 1.00 44.65 ? 81 GLU A OE2 1 ATOM 622 N N . ASP A 1 82 ? -31.833 -20.275 26.676 1.00 25.69 ? 82 ASP A N 1 ATOM 623 C CA . ASP A 1 82 ? -30.844 -20.838 25.772 1.00 27.31 ? 82 ASP A CA 1 ATOM 624 C C . ASP A 1 82 ? -29.757 -21.655 26.468 1.00 23.83 ? 82 ASP A C 1 ATOM 625 O O . ASP A 1 82 ? -28.881 -22.200 25.794 1.00 24.79 ? 82 ASP A O 1 ATOM 626 C CB . ASP A 1 82 ? -30.211 -19.747 24.906 1.00 26.63 ? 82 ASP A CB 1 ATOM 627 C CG . ASP A 1 82 ? -31.231 -19.033 24.037 1.00 30.57 ? 82 ASP A CG 1 ATOM 628 O OD1 . ASP A 1 82 ? -32.256 -19.662 23.685 1.00 24.93 ? 82 ASP A OD1 1 ATOM 629 O OD2 . ASP A 1 82 ? -31.014 -17.844 23.713 1.00 28.86 ? 82 ASP A OD2 1 ATOM 630 N N . ILE A 1 83 ? -29.793 -21.727 27.802 1.00 26.23 ? 83 ILE A N 1 ATOM 631 C CA . ILE A 1 83 ? -28.869 -22.587 28.546 1.00 23.69 ? 83 ILE A CA 1 ATOM 632 C C . ILE A 1 83 ? -29.058 -24.021 28.070 1.00 19.02 ? 83 ILE A C 1 ATOM 633 O O . ILE A 1 83 ? -30.152 -24.560 28.154 1.00 21.77 ? 83 ILE A O 1 ATOM 634 C CB . ILE A 1 83 ? -29.090 -22.506 30.078 1.00 25.83 ? 83 ILE A CB 1 ATOM 635 C CG1 . ILE A 1 83 ? -28.686 -21.127 30.605 1.00 27.30 ? 83 ILE A CG1 1 ATOM 636 C CG2 . ILE A 1 83 ? -28.278 -23.590 30.800 1.00 26.15 ? 83 ILE A CG2 1 ATOM 637 C CD1 . ILE A 1 83 ? -29.138 -20.848 32.040 1.00 28.13 ? 83 ILE A CD1 1 ATOM 638 N N . ALA A 1 84 ? -27.992 -24.612 27.544 1.00 20.13 ? 84 ALA A N 1 ATOM 639 C CA . ALA A 1 84 ? -28.044 -25.932 26.926 1.00 19.41 ? 84 ALA A CA 1 ATOM 640 C C . ALA A 1 84 ? -26.682 -26.289 26.374 1.00 19.34 ? 84 ALA A C 1 ATOM 641 O O . ALA A 1 84 ? -25.763 -25.475 26.376 1.00 17.59 ? 84 ALA A O 1 ATOM 642 C CB . ALA A 1 84 ? -29.067 -25.970 25.785 1.00 15.65 ? 84 ALA A CB 1 ATOM 643 N N . ASP A 1 85 ? -26.578 -27.514 25.876 1.00 18.25 ? 85 ASP A N 1 ATOM 644 C CA . ASP A 1 85 ? -25.468 -27.901 25.030 1.00 22.57 ? 85 ASP A CA 1 ATOM 645 C C . ASP A 1 85 ? -25.892 -27.837 23.558 1.00 21.11 ? 85 ASP A C 1 ATOM 646 O O . ASP A 1 85 ? -27.069 -27.964 23.225 1.00 20.88 ? 85 ASP A O 1 ATOM 647 C CB . ASP A 1 85 ? -24.980 -29.295 25.399 1.00 23.73 ? 85 ASP A CB 1 ATOM 648 C CG . ASP A 1 85 ? -24.741 -29.442 26.885 1.00 28.60 ? 85 ASP A CG 1 ATOM 649 O OD1 . ASP A 1 85 ? -24.316 -28.448 27.518 1.00 33.69 ? 85 ASP A OD1 1 ATOM 650 O OD2 . ASP A 1 85 ? -24.989 -30.540 27.424 1.00 29.85 ? 85 ASP A OD2 1 ATOM 651 N N . TYR A 1 86 ? -24.920 -27.638 22.680 1.00 25.65 ? 86 TYR A N 1 ATOM 652 C CA . TYR A 1 86 ? -25.194 -27.470 21.264 1.00 17.39 ? 86 TYR A CA 1 ATOM 653 C C . TYR A 1 86 ? -24.314 -28.400 20.456 1.00 22.53 ? 86 TYR A C 1 ATOM 654 O O . TYR A 1 86 ? -23.099 -28.436 20.656 1.00 26.90 ? 86 TYR A O 1 ATOM 655 C CB . TYR A 1 86 ? -25.005 -26.002 20.868 1.00 17.93 ? 86 TYR A CB 1 ATOM 656 C CG . TYR A 1 86 ? -26.098 -25.127 21.442 1.00 19.39 ? 86 TYR A CG 1 ATOM 657 C CD1 . TYR A 1 86 ? -26.003 -24.610 22.736 1.00 17.49 ? 86 TYR A CD1 1 ATOM 658 C CD2 . TYR A 1 86 ? -27.250 -24.864 20.713 1.00 15.44 ? 86 TYR A CD2 1 ATOM 659 C CE1 . TYR A 1 86 ? -27.013 -23.831 23.268 1.00 16.90 ? 86 TYR A CE1 1 ATOM 660 C CE2 . TYR A 1 86 ? -28.266 -24.085 21.236 1.00 18.19 ? 86 TYR A CE2 1 ATOM 661 C CZ . TYR A 1 86 ? -28.144 -23.570 22.514 1.00 19.55 ? 86 TYR A CZ 1 ATOM 662 O OH . TYR A 1 86 ? -29.161 -22.807 23.037 1.00 17.51 ? 86 TYR A OH 1 ATOM 663 N N . TYR A 1 87 ? -24.933 -29.170 19.562 1.00 20.15 ? 87 TYR A N 1 ATOM 664 C CA . TYR A 1 87 ? -24.212 -30.158 18.761 1.00 20.80 ? 87 TYR A CA 1 ATOM 665 C C . TYR A 1 87 ? -24.342 -29.875 17.263 1.00 23.78 ? 87 TYR A C 1 ATOM 666 O O . TYR A 1 87 ? -25.395 -29.422 16.784 1.00 23.11 ? 87 TYR A O 1 ATOM 667 C CB . TYR A 1 87 ? -24.724 -31.579 19.055 1.00 17.50 ? 87 TYR A CB 1 ATOM 668 C CG . TYR A 1 87 ? -24.477 -32.053 20.474 1.00 19.34 ? 87 TYR A CG 1 ATOM 669 C CD1 . TYR A 1 87 ? -25.416 -31.829 21.475 1.00 16.62 ? 87 TYR A CD1 1 ATOM 670 C CD2 . TYR A 1 87 ? -23.308 -32.717 20.814 1.00 17.52 ? 87 TYR A CD2 1 ATOM 671 C CE1 . TYR A 1 87 ? -25.200 -32.253 22.780 1.00 16.17 ? 87 TYR A CE1 1 ATOM 672 C CE2 . TYR A 1 87 ? -23.078 -33.143 22.107 1.00 16.51 ? 87 TYR A CE2 1 ATOM 673 C CZ . TYR A 1 87 ? -24.035 -32.907 23.088 1.00 15.47 ? 87 TYR A CZ 1 ATOM 674 O OH . TYR A 1 87 ? -23.831 -33.319 24.379 1.00 22.83 ? 87 TYR A OH 1 ATOM 675 N N . CYS A 1 88 ? -23.277 -30.145 16.518 1.00 22.34 ? 88 CYS A N 1 ATOM 676 C CA . CYS A 1 88 ? -23.369 -30.137 15.064 1.00 20.89 ? 88 CYS A CA 1 ATOM 677 C C . CYS A 1 88 ? -23.328 -31.570 14.519 1.00 20.98 ? 88 CYS A C 1 ATOM 678 O O . CYS A 1 88 ? -22.827 -32.479 15.172 1.00 18.51 ? 88 CYS A O 1 ATOM 679 C CB . CYS A 1 88 ? -22.257 -29.287 14.464 1.00 18.01 ? 88 CYS A CB 1 ATOM 680 S SG . CYS A 1 88 ? -20.630 -29.911 14.848 1.00 24.40 ? 88 CYS A SG 1 ATOM 681 N N . GLN A 1 89 ? -23.878 -31.764 13.327 1.00 21.31 ? 89 GLN A N 1 ATOM 682 C CA . GLN A 1 89 ? -23.978 -33.086 12.721 1.00 16.83 ? 89 GLN A CA 1 ATOM 683 C C . GLN A 1 89 ? -23.660 -32.961 11.242 1.00 21.05 ? 89 GLN A C 1 ATOM 684 O O . GLN A 1 89 ? -24.195 -32.068 10.576 1.00 23.39 ? 89 GLN A O 1 ATOM 685 C CB . GLN A 1 89 ? -25.400 -33.614 12.884 1.00 16.22 ? 89 GLN A CB 1 ATOM 686 C CG . GLN A 1 89 ? -25.657 -34.969 12.237 1.00 14.27 ? 89 GLN A CG 1 ATOM 687 C CD . GLN A 1 89 ? -27.118 -35.183 11.866 1.00 17.17 ? 89 GLN A CD 1 ATOM 688 O OE1 . GLN A 1 89 ? -27.946 -34.277 12.002 1.00 19.14 ? 89 GLN A OE1 1 ATOM 689 N NE2 . GLN A 1 89 ? -27.441 -36.382 11.381 1.00 14.69 ? 89 GLN A NE2 1 ATOM 690 N N . GLN A 1 90 ? -22.786 -33.827 10.723 1.00 22.19 ? 90 GLN A N 1 ATOM 691 C CA . GLN A 1 90 ? -22.481 -33.825 9.286 1.00 21.94 ? 90 GLN A CA 1 ATOM 692 C C . GLN A 1 90 ? -23.141 -35.008 8.626 1.00 21.51 ? 90 GLN A C 1 ATOM 693 O O . GLN A 1 90 ? -23.238 -36.074 9.221 1.00 21.82 ? 90 GLN A O 1 ATOM 694 C CB . GLN A 1 90 ? -20.968 -33.863 8.998 1.00 22.07 ? 90 GLN A CB 1 ATOM 695 C CG . GLN A 1 90 ? -20.259 -35.225 9.218 1.00 21.93 ? 90 GLN A CG 1 ATOM 696 C CD . GLN A 1 90 ? -20.468 -36.240 8.086 1.00 24.91 ? 90 GLN A CD 1 ATOM 697 O OE1 . GLN A 1 90 ? -20.778 -35.878 6.943 1.00 22.63 ? 90 GLN A OE1 1 ATOM 698 N NE2 . GLN A 1 90 ? -20.321 -37.522 8.414 1.00 24.15 ? 90 GLN A NE2 1 ATOM 699 N N . ASN A 1 91 ? -23.565 -34.836 7.382 1.00 25.31 ? 91 ASN A N 1 ATOM 700 C CA . ASN A 1 91 ? -24.108 -35.952 6.631 1.00 24.04 ? 91 ASN A CA 1 ATOM 701 C C . ASN A 1 91 ? -23.719 -35.929 5.145 1.00 27.82 ? 91 ASN A C 1 ATOM 702 O O . ASN A 1 91 ? -24.449 -36.414 4.271 1.00 28.07 ? 91 ASN A O 1 ATOM 703 C CB . ASN A 1 91 ? -25.615 -36.010 6.784 1.00 19.81 ? 91 ASN A CB 1 ATOM 704 C CG . ASN A 1 91 ? -26.185 -37.318 6.312 1.00 25.01 ? 91 ASN A CG 1 ATOM 705 O OD1 . ASN A 1 91 ? -25.612 -38.386 6.555 1.00 24.35 ? 91 ASN A OD1 1 ATOM 706 N ND2 . ASN A 1 91 ? -27.308 -37.245 5.609 1.00 20.64 ? 91 ASN A ND2 1 ATOM 707 N N . ASN A 1 92 ? -22.563 -35.358 4.858 1.00 25.88 ? 92 ASN A N 1 ATOM 708 C CA . ASN A 1 92 ? -22.049 -35.390 3.510 1.00 23.42 ? 92 ASN A CA 1 ATOM 709 C C . ASN A 1 92 ? -21.490 -36.781 3.236 1.00 22.72 ? 92 ASN A C 1 ATOM 710 O O . ASN A 1 92 ? -21.538 -37.256 2.106 1.00 25.34 ? 92 ASN A O 1 ATOM 711 C CB . ASN A 1 92 ? -20.989 -34.302 3.317 1.00 25.08 ? 92 ASN A CB 1 ATOM 712 C CG . ASN A 1 92 ? -20.502 -34.209 1.884 1.00 32.91 ? 92 ASN A CG 1 ATOM 713 O OD1 . ASN A 1 92 ? -21.189 -33.667 1.013 1.00 29.14 ? 92 ASN A OD1 1 ATOM 714 N ND2 . ASN A 1 92 ? -19.307 -34.730 1.634 1.00 27.48 ? 92 ASN A ND2 1 ATOM 715 N N . ASN A 1 93 ? -21.000 -37.428 4.297 1.00 27.01 ? 93 ASN A N 1 ATOM 716 C CA . ASN A 1 93 ? -20.353 -38.747 4.246 1.00 25.11 ? 93 ASN A CA 1 ATOM 717 C C . ASN A 1 93 ? -21.050 -39.737 5.158 1.00 27.23 ? 93 ASN A C 1 ATOM 718 O O . ASN A 1 93 ? -21.442 -39.393 6.270 1.00 24.02 ? 93 ASN A O 1 ATOM 719 C CB . ASN A 1 93 ? -18.894 -38.666 4.719 1.00 19.31 ? 93 ASN A CB 1 ATOM 720 C CG . ASN A 1 93 ? -17.996 -37.928 3.743 1.00 42.81 ? 93 ASN A CG 1 ATOM 721 O OD1 . ASN A 1 93 ? -18.199 -36.740 3.447 1.00 42.19 ? 93 ASN A OD1 1 ATOM 722 N ND2 . ASN A 1 93 ? -16.974 -38.623 3.252 1.00 49.40 ? 93 ASN A ND2 1 ATOM 723 N N . TRP A 1 94 ? -21.178 -40.976 4.703 1.00 27.12 ? 94 TRP A N 1 ATOM 724 C CA . TRP A 1 94 ? -21.730 -42.030 5.531 1.00 25.21 ? 94 TRP A CA 1 ATOM 725 C C . TRP A 1 94 ? -20.586 -42.596 6.373 1.00 27.75 ? 94 TRP A C 1 ATOM 726 O O . TRP A 1 94 ? -19.497 -42.790 5.846 1.00 29.84 ? 94 TRP A O 1 ATOM 727 C CB . TRP A 1 94 ? -22.342 -43.121 4.644 1.00 20.16 ? 94 TRP A CB 1 ATOM 728 C CG . TRP A 1 94 ? -23.124 -44.150 5.399 1.00 19.12 ? 94 TRP A CG 1 ATOM 729 C CD1 . TRP A 1 94 ? -24.474 -44.188 5.567 1.00 19.39 ? 94 TRP A CD1 1 ATOM 730 C CD2 . TRP A 1 94 ? -22.599 -45.283 6.110 1.00 23.30 ? 94 TRP A CD2 1 ATOM 731 N NE1 . TRP A 1 94 ? -24.825 -45.270 6.326 1.00 16.92 ? 94 TRP A NE1 1 ATOM 732 C CE2 . TRP A 1 94 ? -23.695 -45.959 6.677 1.00 24.59 ? 94 TRP A CE2 1 ATOM 733 C CE3 . TRP A 1 94 ? -21.307 -45.789 6.322 1.00 21.69 ? 94 TRP A CE3 1 ATOM 734 C CZ2 . TRP A 1 94 ? -23.547 -47.122 7.441 1.00 25.21 ? 94 TRP A CZ2 1 ATOM 735 C CZ3 . TRP A 1 94 ? -21.157 -46.947 7.085 1.00 18.22 ? 94 TRP A CZ3 1 ATOM 736 C CH2 . TRP A 1 94 ? -22.271 -47.598 7.636 1.00 22.16 ? 94 TRP A CH2 1 ATOM 737 N N . PRO A 1 95 ? -20.822 -42.852 7.681 1.00 26.12 ? 95 PRO A N 1 ATOM 738 C CA . PRO A 1 95 ? -22.096 -42.626 8.383 1.00 24.88 ? 95 PRO A CA 1 ATOM 739 C C . PRO A 1 95 ? -22.172 -41.198 8.905 1.00 20.06 ? 95 PRO A C 1 ATOM 740 O O . PRO A 1 95 ? -21.126 -40.564 9.029 1.00 20.41 ? 95 PRO A O 1 ATOM 741 C CB . PRO A 1 95 ? -22.013 -43.610 9.558 1.00 25.04 ? 95 PRO A CB 1 ATOM 742 C CG . PRO A 1 95 ? -20.520 -43.644 9.889 1.00 21.75 ? 95 PRO A CG 1 ATOM 743 C CD . PRO A 1 95 ? -19.799 -43.450 8.569 1.00 27.11 ? 95 PRO A CD 1 ATOM 744 N N . THR A 1 96 ? -23.375 -40.702 9.197 1.00 19.40 ? 96 THR A N 1 ATOM 745 C CA . THR A 1 96 ? -23.526 -39.378 9.786 1.00 15.41 ? 96 THR A CA 1 ATOM 746 C C . THR A 1 96 ? -22.823 -39.367 11.144 1.00 18.29 ? 96 THR A C 1 ATOM 747 O O . THR A 1 96 ? -22.868 -40.356 11.868 1.00 16.05 ? 96 THR A O 1 ATOM 748 C CB . THR A 1 96 ? -25.011 -38.970 9.907 1.00 20.27 ? 96 THR A CB 1 ATOM 749 O OG1 . THR A 1 96 ? -25.112 -37.618 10.369 1.00 16.15 ? 96 THR A OG1 1 ATOM 750 C CG2 . THR A 1 96 ? -25.769 -39.890 10.860 1.00 16.13 ? 96 THR A CG2 1 ATOM 751 N N . THR A 1 97 ? -22.118 -38.279 11.450 1.00 21.30 ? 97 THR A N 1 ATOM 752 C CA . THR A 1 97 ? -21.389 -38.157 12.712 1.00 17.33 ? 97 THR A CA 1 ATOM 753 C C . THR A 1 97 ? -21.652 -36.818 13.395 1.00 21.16 ? 97 THR A C 1 ATOM 754 O O . THR A 1 97 ? -21.956 -35.823 12.740 1.00 23.65 ? 97 THR A O 1 ATOM 755 C CB . THR A 1 97 ? -19.851 -38.315 12.525 1.00 21.81 ? 97 THR A CB 1 ATOM 756 O OG1 . THR A 1 97 ? -19.383 -37.428 11.496 1.00 23.90 ? 97 THR A OG1 1 ATOM 757 C CG2 . THR A 1 97 ? -19.494 -39.737 12.154 1.00 22.51 ? 97 THR A CG2 1 ATOM 758 N N . PHE A 1 98 ? -21.524 -36.790 14.716 1.00 19.48 ? 98 PHE A N 1 ATOM 759 C CA . PHE A 1 98 ? -21.817 -35.586 15.486 1.00 17.08 ? 98 PHE A CA 1 ATOM 760 C C . PHE A 1 98 ? -20.564 -35.095 16.148 1.00 17.59 ? 98 PHE A C 1 ATOM 761 O O . PHE A 1 98 ? -19.673 -35.887 16.450 1.00 24.98 ? 98 PHE A O 1 ATOM 762 C CB . PHE A 1 98 ? -22.802 -35.886 16.612 1.00 19.24 ? 98 PHE A CB 1 ATOM 763 C CG . PHE A 1 98 ? -24.152 -36.326 16.151 1.00 20.27 ? 98 PHE A CG 1 ATOM 764 C CD1 . PHE A 1 98 ? -24.374 -37.644 15.789 1.00 18.01 ? 98 PHE A CD1 1 ATOM 765 C CD2 . PHE A 1 98 ? -25.209 -35.436 16.125 1.00 17.36 ? 98 PHE A CD2 1 ATOM 766 C CE1 . PHE A 1 98 ? -25.612 -38.059 15.385 1.00 16.79 ? 98 PHE A CE1 1 ATOM 767 C CE2 . PHE A 1 98 ? -26.449 -35.845 15.727 1.00 16.53 ? 98 PHE A CE2 1 ATOM 768 C CZ . PHE A 1 98 ? -26.651 -37.160 15.351 1.00 19.96 ? 98 PHE A CZ 1 ATOM 769 N N . GLY A 1 99 ? -20.504 -33.794 16.407 1.00 14.62 ? 99 GLY A N 1 ATOM 770 C CA . GLY A 1 99 ? -19.436 -33.243 17.228 1.00 25.76 ? 99 GLY A CA 1 ATOM 771 C C . GLY A 1 99 ? -19.634 -33.581 18.700 1.00 17.98 ? 99 GLY A C 1 ATOM 772 O O . GLY A 1 99 ? -20.578 -34.289 19.061 1.00 23.19 ? 99 GLY A O 1 ATOM 773 N N . ALA A 1 100 ? -18.762 -33.065 19.553 1.00 14.17 ? 100 ALA A N 1 ATOM 774 C CA . ALA A 1 100 ? -18.777 -33.433 20.964 1.00 17.39 ? 100 ALA A CA 1 ATOM 775 C C . ALA A 1 100 ? -19.626 -32.474 21.794 1.00 25.51 ? 100 ALA A C 1 ATOM 776 O O . ALA A 1 100 ? -19.919 -32.739 22.957 1.00 22.80 ? 100 ALA A O 1 ATOM 777 C CB . ALA A 1 100 ? -17.356 -33.508 21.514 1.00 9.79 ? 100 ALA A CB 1 ATOM 778 N N . GLY A 1 101 ? -20.018 -31.356 21.188 1.00 21.99 ? 101 GLY A N 1 ATOM 779 C CA . GLY A 1 101 ? -20.878 -30.392 21.848 1.00 21.45 ? 101 GLY A CA 1 ATOM 780 C C . GLY A 1 101 ? -20.158 -29.233 22.518 1.00 25.18 ? 101 GLY A C 1 ATOM 781 O O . GLY A 1 101 ? -19.022 -29.366 22.962 1.00 25.20 ? 101 GLY A O 1 ATOM 782 N N . THR A 1 102 ? -20.841 -28.095 22.578 1.00 17.49 ? 102 THR A N 1 ATOM 783 C CA . THR A 1 102 ? -20.371 -26.928 23.294 1.00 21.73 ? 102 THR A CA 1 ATOM 784 C C . THR A 1 102 ? -21.413 -26.562 24.368 1.00 24.62 ? 102 THR A C 1 ATOM 785 O O . THR A 1 102 ? -22.622 -26.543 24.100 1.00 21.45 ? 102 THR A O 1 ATOM 786 C CB . THR A 1 102 ? -20.157 -25.743 22.314 1.00 22.97 ? 102 THR A CB 1 ATOM 787 O OG1 . THR A 1 102 ? -19.049 -26.035 21.459 1.00 30.00 ? 102 THR A OG1 1 ATOM 788 C CG2 . THR A 1 102 ? -19.867 -24.460 23.048 1.00 22.96 ? 102 THR A CG2 1 ATOM 789 N N . LYS A 1 103 ? -20.947 -26.292 25.583 1.00 21.30 ? 103 LYS A N 1 ATOM 790 C CA . LYS A 1 103 ? -21.825 -25.900 26.676 1.00 19.20 ? 103 LYS A CA 1 ATOM 791 C C . LYS A 1 103 ? -22.009 -24.384 26.688 1.00 24.54 ? 103 LYS A C 1 ATOM 792 O O . LYS A 1 103 ? -21.034 -23.630 26.614 1.00 26.01 ? 103 LYS A O 1 ATOM 793 C CB . LYS A 1 103 ? -21.232 -26.364 28.006 1.00 25.96 ? 103 LYS A CB 1 ATOM 794 C CG . LYS A 1 103 ? -22.033 -25.976 29.234 1.00 21.73 ? 103 LYS A CG 1 ATOM 795 C CD . LYS A 1 103 ? -21.912 -27.053 30.302 1.00 27.39 ? 103 LYS A CD 1 ATOM 796 C CE . LYS A 1 103 ? -22.557 -26.627 31.604 1.00 35.10 ? 103 LYS A CE 1 ATOM 797 N NZ . LYS A 1 103 ? -22.713 -27.764 32.559 1.00 37.02 ? 103 LYS A NZ 1 ATOM 798 N N . LEU A 1 104 ? -23.260 -23.938 26.762 1.00 22.54 ? 104 LEU A N 1 ATOM 799 C CA . LEU A 1 104 ? -23.548 -22.520 26.906 1.00 23.32 ? 104 LEU A CA 1 ATOM 800 C C . LEU A 1 104 ? -24.012 -22.192 28.335 1.00 20.92 ? 104 LEU A C 1 ATOM 801 O O . LEU A 1 104 ? -25.047 -22.659 28.782 1.00 21.42 ? 104 LEU A O 1 ATOM 802 C CB . LEU A 1 104 ? -24.584 -22.062 25.875 1.00 17.44 ? 104 LEU A CB 1 ATOM 803 C CG . LEU A 1 104 ? -24.937 -20.577 26.024 1.00 19.35 ? 104 LEU A CG 1 ATOM 804 C CD1 . LEU A 1 104 ? -23.805 -19.705 25.499 1.00 19.11 ? 104 LEU A CD1 1 ATOM 805 C CD2 . LEU A 1 104 ? -26.269 -20.207 25.383 1.00 17.95 ? 104 LEU A CD2 1 ATOM 806 N N . GLU A 1 105 ? -23.222 -21.397 29.046 1.00 27.46 ? 105 GLU A N 1 ATOM 807 C CA . GLU A 1 105 ? -23.565 -20.969 30.396 1.00 27.05 ? 105 GLU A CA 1 ATOM 808 C C . GLU A 1 105 ? -23.890 -19.483 30.401 1.00 26.05 ? 105 GLU A C 1 ATOM 809 O O . GLU A 1 105 ? -23.296 -18.705 29.651 1.00 24.28 ? 105 GLU A O 1 ATOM 810 C CB . GLU A 1 105 ? -22.400 -21.229 31.350 1.00 25.56 ? 105 GLU A CB 1 ATOM 811 C CG . GLU A 1 105 ? -21.783 -22.599 31.211 1.00 32.56 ? 105 GLU A CG 1 ATOM 812 C CD . GLU A 1 105 ? -21.024 -23.010 32.459 1.00 45.58 ? 105 GLU A CD 1 ATOM 813 O OE1 . GLU A 1 105 ? -19.848 -22.606 32.582 1.00 39.51 ? 105 GLU A OE1 1 ATOM 814 O OE2 . GLU A 1 105 ? -21.611 -23.727 33.315 1.00 49.92 ? 105 GLU A OE2 1 ATOM 815 N N . LEU A 1 106 ? -24.829 -19.089 31.253 1.00 25.43 ? 106 LEU A N 1 ATOM 816 C CA . LEU A 1 106 ? -25.200 -17.690 31.360 1.00 22.56 ? 106 LEU A CA 1 ATOM 817 C C . LEU A 1 106 ? -24.676 -17.026 32.615 1.00 29.93 ? 106 LEU A C 1 ATOM 818 O O . LEU A 1 106 ? -24.798 -17.571 33.719 1.00 33.01 ? 106 LEU A O 1 ATOM 819 C CB . LEU A 1 106 ? -26.705 -17.515 31.293 1.00 23.34 ? 106 LEU A CB 1 ATOM 820 C CG . LEU A 1 106 ? -27.077 -16.913 29.944 1.00 30.11 ? 106 LEU A CG 1 ATOM 821 C CD1 . LEU A 1 106 ? -26.926 -18.022 28.936 1.00 36.14 ? 106 LEU A CD1 1 ATOM 822 C CD2 . LEU A 1 106 ? -28.472 -16.321 29.942 1.00 26.37 ? 106 LEU A CD2 1 ATOM 823 N N . LYS A 1 107 ? -24.087 -15.848 32.441 1.00 26.70 ? 107 LYS A N 1 ATOM 824 C CA . LYS A 1 107 ? -23.726 -15.018 33.574 1.00 25.86 ? 107 LYS A CA 1 ATOM 825 C C . LYS A 1 107 ? -24.977 -14.312 34.085 1.00 28.75 ? 107 LYS A C 1 ATOM 826 O O . LYS A 1 107 ? -25.948 -14.095 33.353 1.00 26.89 ? 107 LYS A O 1 ATOM 827 C CB . LYS A 1 107 ? -22.677 -13.978 33.194 1.00 29.13 ? 107 LYS A CB 1 ATOM 828 C CG . LYS A 1 107 ? -21.325 -14.534 32.796 1.00 33.58 ? 107 LYS A CG 1 ATOM 829 C CD . LYS A 1 107 ? -20.319 -13.407 32.584 1.00 30.59 ? 107 LYS A CD 1 ATOM 830 C CE . LYS A 1 107 ? -19.078 -13.898 31.847 1.00 35.30 ? 107 LYS A CE 1 ATOM 831 N NZ . LYS A 1 107 ? -18.561 -15.143 32.465 1.00 49.42 ? 107 LYS A NZ 1 ATOM 832 N N . ARG A 1 108 ? -24.950 -13.981 35.362 1.00 22.83 ? 108 ARG A N 1 ATOM 833 C CA . ARG A 1 108 ? -25.958 -13.124 35.939 1.00 20.99 ? 108 ARG A CA 1 ATOM 834 C C . ARG A 1 108 ? -25.348 -12.438 37.149 1.00 23.59 ? 108 ARG A C 1 ATOM 835 O O . ARG A 1 108 ? -24.172 -12.631 37.462 1.00 22.98 ? 108 ARG A O 1 ATOM 836 C CB . ARG A 1 108 ? -27.192 -13.925 36.327 1.00 27.10 ? 108 ARG A CB 1 ATOM 837 C CG . ARG A 1 108 ? -26.929 -15.089 37.264 1.00 16.80 ? 108 ARG A CG 1 ATOM 838 C CD . ARG A 1 108 ? -28.185 -15.336 38.051 1.00 18.76 ? 108 ARG A CD 1 ATOM 839 N NE . ARG A 1 108 ? -28.407 -14.248 39.007 1.00 21.71 ? 108 ARG A NE 1 ATOM 840 C CZ . ARG A 1 108 ? -29.591 -13.910 39.521 1.00 21.11 ? 108 ARG A CZ 1 ATOM 841 N NH1 . ARG A 1 108 ? -30.696 -14.549 39.164 1.00 20.72 ? 108 ARG A NH1 1 ATOM 842 N NH2 . ARG A 1 108 ? -29.670 -12.912 40.391 1.00 20.89 ? 108 ARG A NH2 1 ATOM 843 N N . THR A 1 109 ? -26.144 -11.631 37.826 1.00 20.51 ? 109 THR A N 1 ATOM 844 C CA . THR A 1 109 ? -25.661 -10.959 39.016 1.00 22.53 ? 109 THR A CA 1 ATOM 845 C C . THR A 1 109 ? -25.512 -11.975 40.148 1.00 25.51 ? 109 THR A C 1 ATOM 846 O O . THR A 1 109 ? -26.184 -13.021 40.157 1.00 21.09 ? 109 THR A O 1 ATOM 847 C CB . THR A 1 109 ? -26.627 -9.866 39.446 1.00 19.81 ? 109 THR A CB 1 ATOM 848 O OG1 . THR A 1 109 ? -27.813 -10.476 39.967 1.00 20.34 ? 109 THR A OG1 1 ATOM 849 C CG2 . THR A 1 109 ? -26.985 -8.988 38.251 1.00 21.28 ? 109 THR A CG2 1 ATOM 850 N N . VAL A 1 110 ? -24.625 -11.663 41.090 1.00 17.03 ? 110 VAL A N 1 ATOM 851 C CA . VAL A 1 110 ? -24.454 -12.478 42.287 1.00 18.08 ? 110 VAL A CA 1 ATOM 852 C C . VAL A 1 110 ? -25.757 -12.592 43.090 1.00 15.51 ? 110 VAL A C 1 ATOM 853 O O . VAL A 1 110 ? -26.486 -11.623 43.244 1.00 20.54 ? 110 VAL A O 1 ATOM 854 C CB . VAL A 1 110 ? -23.299 -11.952 43.160 1.00 15.95 ? 110 VAL A CB 1 ATOM 855 C CG1 . VAL A 1 110 ? -23.234 -12.704 44.481 1.00 14.28 ? 110 VAL A CG1 1 ATOM 856 C CG2 . VAL A 1 110 ? -21.980 -12.084 42.403 1.00 12.38 ? 110 VAL A CG2 1 ATOM 857 N N . ALA A 1 111 ? -26.060 -13.799 43.547 1.00 16.77 ? 111 ALA A N 1 ATOM 858 C CA . ALA A 1 111 ? -27.251 -14.047 44.339 1.00 15.82 ? 111 ALA A CA 1 ATOM 859 C C . ALA A 1 111 ? -26.844 -14.990 45.458 1.00 17.21 ? 111 ALA A C 1 ATOM 860 O O . ALA A 1 111 ? -26.345 -16.087 45.198 1.00 19.62 ? 111 ALA A O 1 ATOM 861 C CB . ALA A 1 111 ? -28.345 -14.676 43.485 1.00 11.18 ? 111 ALA A CB 1 ATOM 862 N N . ALA A 1 112 ? -27.019 -14.556 46.696 1.00 12.16 ? 112 ALA A N 1 ATOM 863 C CA . ALA A 1 112 ? -26.656 -15.380 47.837 1.00 14.96 ? 112 ALA A CA 1 ATOM 864 C C . ALA A 1 112 ? -27.670 -16.522 47.945 1.00 15.03 ? 112 ALA A C 1 ATOM 865 O O . ALA A 1 112 ? -28.812 -16.349 47.551 1.00 15.10 ? 112 ALA A O 1 ATOM 866 C CB . ALA A 1 112 ? -26.643 -14.536 49.104 1.00 12.76 ? 112 ALA A CB 1 ATOM 867 N N . PRO A 1 113 ? -27.232 -17.701 48.414 1.00 12.78 ? 113 PRO A N 1 ATOM 868 C CA . PRO A 1 113 ? -28.166 -18.810 48.629 1.00 14.12 ? 113 PRO A CA 1 ATOM 869 C C . PRO A 1 113 ? -29.086 -18.567 49.816 1.00 18.05 ? 113 PRO A C 1 ATOM 870 O O . PRO A 1 113 ? -28.726 -17.833 50.729 1.00 17.15 ? 113 PRO A O 1 ATOM 871 C CB . PRO A 1 113 ? -27.244 -20.003 48.938 1.00 13.47 ? 113 PRO A CB 1 ATOM 872 C CG . PRO A 1 113 ? -25.936 -19.395 49.367 1.00 10.72 ? 113 PRO A CG 1 ATOM 873 C CD . PRO A 1 113 ? -25.826 -18.112 48.591 1.00 14.24 ? 113 PRO A CD 1 ATOM 874 N N . SER A 1 114 ? -30.271 -19.162 49.771 1.00 15.00 ? 114 SER A N 1 ATOM 875 C CA . SER A 1 114 ? -31.077 -19.371 50.955 1.00 13.04 ? 114 SER A CA 1 ATOM 876 C C . SER A 1 114 ? -30.686 -20.746 51.470 1.00 12.30 ? 114 SER A C 1 ATOM 877 O O . SER A 1 114 ? -30.613 -21.703 50.708 1.00 18.02 ? 114 SER A O 1 ATOM 878 C CB . SER A 1 114 ? -32.562 -19.357 50.605 1.00 12.58 ? 114 SER A CB 1 ATOM 879 O OG . SER A 1 114 ? -32.976 -18.079 50.158 1.00 26.19 ? 114 SER A OG 1 ATOM 880 N N . VAL A 1 115 ? -30.416 -20.847 52.759 1.00 17.94 ? 115 VAL A N 1 ATOM 881 C CA . VAL A 1 115 ? -29.984 -22.110 53.334 1.00 15.74 ? 115 VAL A CA 1 ATOM 882 C C . VAL A 1 115 ? -31.060 -22.692 54.222 1.00 16.82 ? 115 VAL A C 1 ATOM 883 O O . VAL A 1 115 ? -31.613 -21.995 55.058 1.00 21.83 ? 115 VAL A O 1 ATOM 884 C CB . VAL A 1 115 ? -28.743 -21.925 54.206 1.00 16.65 ? 115 VAL A CB 1 ATOM 885 C CG1 . VAL A 1 115 ? -28.237 -23.283 54.679 1.00 14.55 ? 115 VAL A CG1 1 ATOM 886 C CG2 . VAL A 1 115 ? -27.671 -21.169 53.450 1.00 13.46 ? 115 VAL A CG2 1 ATOM 887 N N . PHE A 1 116 ? -31.342 -23.976 54.049 1.00 19.57 ? 116 PHE A N 1 ATOM 888 C CA . PHE A 1 116 ? -32.279 -24.668 54.916 1.00 20.36 ? 116 PHE A CA 1 ATOM 889 C C . PHE A 1 116 ? -31.635 -25.971 55.354 1.00 22.34 ? 116 PHE A C 1 ATOM 890 O O . PHE A 1 116 ? -30.912 -26.590 54.573 1.00 22.51 ? 116 PHE A O 1 ATOM 891 C CB . PHE A 1 116 ? -33.585 -24.942 54.174 1.00 20.81 ? 116 PHE A CB 1 ATOM 892 C CG . PHE A 1 116 ? -34.158 -23.736 53.486 1.00 20.47 ? 116 PHE A CG 1 ATOM 893 C CD1 . PHE A 1 116 ? -33.827 -23.449 52.172 1.00 20.27 ? 116 PHE A CD1 1 ATOM 894 C CD2 . PHE A 1 116 ? -35.031 -22.895 54.146 1.00 24.70 ? 116 PHE A CD2 1 ATOM 895 C CE1 . PHE A 1 116 ? -34.346 -22.341 51.532 1.00 20.60 ? 116 PHE A CE1 1 ATOM 896 C CE2 . PHE A 1 116 ? -35.560 -21.790 53.514 1.00 24.37 ? 116 PHE A CE2 1 ATOM 897 C CZ . PHE A 1 116 ? -35.215 -21.512 52.206 1.00 21.25 ? 116 PHE A CZ 1 ATOM 898 N N . ILE A 1 117 ? -31.872 -26.383 56.597 1.00 18.01 ? 117 ILE A N 1 ATOM 899 C CA . ILE A 1 117 ? -31.337 -27.655 57.076 1.00 15.35 ? 117 ILE A CA 1 ATOM 900 C C . ILE A 1 117 ? -32.439 -28.626 57.504 1.00 15.26 ? 117 ILE A C 1 ATOM 901 O O . ILE A 1 117 ? -33.387 -28.253 58.171 1.00 25.41 ? 117 ILE A O 1 ATOM 902 C CB . ILE A 1 117 ? -30.306 -27.455 58.222 1.00 27.77 ? 117 ILE A CB 1 ATOM 903 C CG1 . ILE A 1 117 ? -29.629 -28.785 58.591 1.00 13.70 ? 117 ILE A CG1 1 ATOM 904 C CG2 . ILE A 1 117 ? -30.947 -26.771 59.424 1.00 19.83 ? 117 ILE A CG2 1 ATOM 905 C CD1 . ILE A 1 117 ? -28.438 -28.607 59.482 1.00 16.68 ? 117 ILE A CD1 1 ATOM 906 N N . PHE A 1 118 ? -32.301 -29.880 57.114 1.00 16.42 ? 118 PHE A N 1 ATOM 907 C CA . PHE A 1 118 ? -33.310 -30.893 57.391 1.00 18.76 ? 118 PHE A CA 1 ATOM 908 C C . PHE A 1 118 ? -32.725 -32.052 58.186 1.00 19.18 ? 118 PHE A C 1 ATOM 909 O O . PHE A 1 118 ? -31.888 -32.792 57.677 1.00 18.73 ? 118 PHE A O 1 ATOM 910 C CB . PHE A 1 118 ? -33.852 -31.473 56.082 1.00 18.55 ? 118 PHE A CB 1 ATOM 911 C CG . PHE A 1 118 ? -34.514 -30.471 55.182 1.00 17.47 ? 118 PHE A CG 1 ATOM 912 C CD1 . PHE A 1 118 ? -35.861 -30.159 55.338 1.00 15.43 ? 118 PHE A CD1 1 ATOM 913 C CD2 . PHE A 1 118 ? -33.805 -29.873 54.156 1.00 15.88 ? 118 PHE A CD2 1 ATOM 914 C CE1 . PHE A 1 118 ? -36.488 -29.254 54.484 1.00 17.52 ? 118 PHE A CE1 1 ATOM 915 C CE2 . PHE A 1 118 ? -34.418 -28.972 53.306 1.00 16.27 ? 118 PHE A CE2 1 ATOM 916 C CZ . PHE A 1 118 ? -35.762 -28.662 53.461 1.00 17.38 ? 118 PHE A CZ 1 ATOM 917 N N . PRO A 1 119 ? -33.179 -32.227 59.429 1.00 23.05 ? 119 PRO A N 1 ATOM 918 C CA . PRO A 1 119 ? -32.852 -33.399 60.255 1.00 21.13 ? 119 PRO A CA 1 ATOM 919 C C . PRO A 1 119 ? -33.260 -34.683 59.555 1.00 18.33 ? 119 PRO A C 1 ATOM 920 O O . PRO A 1 119 ? -34.065 -34.626 58.638 1.00 23.55 ? 119 PRO A O 1 ATOM 921 C CB . PRO A 1 119 ? -33.743 -33.216 61.491 1.00 24.47 ? 119 PRO A CB 1 ATOM 922 C CG . PRO A 1 119 ? -34.053 -31.750 61.539 1.00 21.91 ? 119 PRO A CG 1 ATOM 923 C CD . PRO A 1 119 ? -34.063 -31.270 60.118 1.00 22.09 ? 119 PRO A CD 1 ATOM 924 N N . PRO A 1 120 ? -32.720 -35.831 59.986 1.00 22.42 ? 120 PRO A N 1 ATOM 925 C CA . PRO A 1 120 ? -33.217 -37.130 59.515 1.00 15.93 ? 120 PRO A CA 1 ATOM 926 C C . PRO A 1 120 ? -34.673 -37.321 59.914 1.00 24.16 ? 120 PRO A C 1 ATOM 927 O O . PRO A 1 120 ? -35.084 -36.859 60.981 1.00 18.96 ? 120 PRO A O 1 ATOM 928 C CB . PRO A 1 120 ? -32.368 -38.133 60.286 1.00 20.46 ? 120 PRO A CB 1 ATOM 929 C CG . PRO A 1 120 ? -31.214 -37.366 60.831 1.00 18.70 ? 120 PRO A CG 1 ATOM 930 C CD . PRO A 1 120 ? -31.626 -35.957 60.965 1.00 22.62 ? 120 PRO A CD 1 ATOM 931 N N . SER A 1 121 ? -35.450 -37.994 59.071 1.00 27.61 ? 121 SER A N 1 ATOM 932 C CA . SER A 1 121 ? -36.824 -38.344 59.436 1.00 26.11 ? 121 SER A CA 1 ATOM 933 C C . SER A 1 121 ? -36.800 -39.497 60.422 1.00 25.24 ? 121 SER A C 1 ATOM 934 O O . SER A 1 121 ? -35.888 -40.333 60.389 1.00 28.63 ? 121 SER A O 1 ATOM 935 C CB . SER A 1 121 ? -37.620 -38.771 58.203 1.00 25.06 ? 121 SER A CB 1 ATOM 936 O OG . SER A 1 121 ? -37.132 -39.999 57.690 1.00 28.18 ? 121 SER A OG 1 ATOM 937 N N . ASP A 1 122 ? -37.806 -39.553 61.290 1.00 26.75 ? 122 ASP A N 1 ATOM 938 C CA . ASP A 1 122 ? -37.978 -40.705 62.173 1.00 30.37 ? 122 ASP A CA 1 ATOM 939 C C . ASP A 1 122 ? -38.151 -41.956 61.325 1.00 30.31 ? 122 ASP A C 1 ATOM 940 O O . ASP A 1 122 ? -37.757 -43.049 61.722 1.00 30.28 ? 122 ASP A O 1 ATOM 941 C CB . ASP A 1 122 ? -39.180 -40.506 63.099 1.00 32.09 ? 122 ASP A CB 1 ATOM 942 C CG . ASP A 1 122 ? -38.963 -39.376 64.096 1.00 45.94 ? 122 ASP A CG 1 ATOM 943 O OD1 . ASP A 1 122 ? -37.798 -39.163 64.500 1.00 47.05 ? 122 ASP A OD1 1 ATOM 944 O OD2 . ASP A 1 122 ? -39.945 -38.694 64.469 1.00 52.16 ? 122 ASP A OD2 1 ATOM 945 N N . GLU A 1 123 ? -38.734 -41.767 60.144 1.00 23.70 ? 123 GLU A N 1 ATOM 946 C CA . GLU A 1 123 ? -38.903 -42.834 59.174 1.00 31.75 ? 123 GLU A CA 1 ATOM 947 C C . GLU A 1 123 ? -37.555 -43.415 58.777 1.00 28.00 ? 123 GLU A C 1 ATOM 948 O O . GLU A 1 123 ? -37.359 -44.630 58.837 1.00 32.37 ? 123 GLU A O 1 ATOM 949 C CB . GLU A 1 123 ? -39.645 -42.328 57.926 1.00 34.76 ? 123 GLU A CB 1 ATOM 950 C CG . GLU A 1 123 ? -41.123 -41.992 58.152 1.00 37.97 ? 123 GLU A CG 1 ATOM 951 C CD . GLU A 1 123 ? -41.360 -40.617 58.792 1.00 41.20 ? 123 GLU A CD 1 ATOM 952 O OE1 . GLU A 1 123 ? -40.393 -39.973 59.246 1.00 34.59 ? 123 GLU A OE1 1 ATOM 953 O OE2 . GLU A 1 123 ? -42.531 -40.176 58.843 1.00 50.92 ? 123 GLU A OE2 1 ATOM 954 N N . GLN A 1 124 ? -36.628 -42.554 58.372 1.00 24.66 ? 124 GLN A N 1 ATOM 955 C CA . GLN A 1 124 ? -35.303 -43.037 57.987 1.00 32.46 ? 124 GLN A CA 1 ATOM 956 C C . GLN A 1 124 ? -34.557 -43.672 59.166 1.00 30.25 ? 124 GLN A C 1 ATOM 957 O O . GLN A 1 124 ? -33.887 -44.695 59.009 1.00 29.91 ? 124 GLN A O 1 ATOM 958 C CB . GLN A 1 124 ? -34.453 -41.940 57.338 1.00 26.73 ? 124 GLN A CB 1 ATOM 959 C CG . GLN A 1 124 ? -33.097 -42.474 56.874 1.00 23.85 ? 124 GLN A CG 1 ATOM 960 C CD . GLN A 1 124 ? -32.166 -41.389 56.402 1.00 22.43 ? 124 GLN A CD 1 ATOM 961 O OE1 . GLN A 1 124 ? -32.421 -40.204 56.609 1.00 26.86 ? 124 GLN A OE1 1 ATOM 962 N NE2 . GLN A 1 124 ? -31.080 -41.784 55.753 1.00 24.26 ? 124 GLN A NE2 1 ATOM 963 N N . LEU A 1 125 ? -34.679 -43.059 60.340 1.00 28.41 ? 125 LEU A N 1 ATOM 964 C CA . LEU A 1 125 ? -33.998 -43.554 61.534 1.00 31.82 ? 125 LEU A CA 1 ATOM 965 C C . LEU A 1 125 ? -34.310 -45.027 61.840 1.00 35.59 ? 125 LEU A C 1 ATOM 966 O O . LEU A 1 125 ? -33.444 -45.754 62.338 1.00 33.83 ? 125 LEU A O 1 ATOM 967 C CB . LEU A 1 125 ? -34.310 -42.671 62.744 1.00 26.95 ? 125 LEU A CB 1 ATOM 968 C CG . LEU A 1 125 ? -33.577 -41.334 62.731 1.00 28.60 ? 125 LEU A CG 1 ATOM 969 C CD1 . LEU A 1 125 ? -33.931 -40.509 63.935 1.00 29.08 ? 125 LEU A CD1 1 ATOM 970 C CD2 . LEU A 1 125 ? -32.097 -41.580 62.685 1.00 33.31 ? 125 LEU A CD2 1 ATOM 971 N N . LYS A 1 126 ? -35.526 -45.465 61.514 1.00 28.06 ? 126 LYS A N 1 ATOM 972 C CA . LYS A 1 126 ? -35.916 -46.865 61.685 1.00 35.02 ? 126 LYS A CA 1 ATOM 973 C C . LYS A 1 126 ? -35.079 -47.862 60.876 1.00 34.75 ? 126 LYS A C 1 ATOM 974 O O . LYS A 1 126 ? -35.173 -49.061 61.106 1.00 41.52 ? 126 LYS A O 1 ATOM 975 C CB . LYS A 1 126 ? -37.395 -47.070 61.339 1.00 32.33 ? 126 LYS A CB 1 ATOM 976 C CG . LYS A 1 126 ? -38.375 -46.414 62.290 1.00 35.99 ? 126 LYS A CG 1 ATOM 977 C CD . LYS A 1 126 ? -39.794 -46.852 61.980 1.00 43.63 ? 126 LYS A CD 1 ATOM 978 C CE . LYS A 1 126 ? -40.789 -46.131 62.867 1.00 50.48 ? 126 LYS A CE 1 ATOM 979 N NZ . LYS A 1 126 ? -42.189 -46.300 62.389 1.00 59.34 ? 126 LYS A NZ 1 ATOM 980 N N . SER A 1 127 ? -34.279 -47.380 59.927 1.00 35.81 ? 127 SER A N 1 ATOM 981 C CA . SER A 1 127 ? -33.481 -48.266 59.080 1.00 31.01 ? 127 SER A CA 1 ATOM 982 C C . SER A 1 127 ? -32.027 -48.385 59.539 1.00 36.50 ? 127 SER A C 1 ATOM 983 O O . SER A 1 127 ? -31.264 -49.199 59.013 1.00 36.08 ? 127 SER A O 1 ATOM 984 C CB . SER A 1 127 ? -33.522 -47.791 57.624 1.00 43.75 ? 127 SER A CB 1 ATOM 985 O OG . SER A 1 127 ? -32.891 -46.525 57.478 1.00 45.14 ? 127 SER A OG 1 ATOM 986 N N . GLY A 1 128 ? -31.638 -47.570 60.512 1.00 32.44 ? 128 GLY A N 1 ATOM 987 C CA . GLY A 1 128 ? -30.283 -47.621 61.031 1.00 39.18 ? 128 GLY A CA 1 ATOM 988 C C . GLY A 1 128 ? -29.338 -46.722 60.259 1.00 42.67 ? 128 GLY A C 1 ATOM 989 O O . GLY A 1 128 ? -28.118 -46.931 60.243 1.00 35.33 ? 128 GLY A O 1 ATOM 990 N N . THR A 1 129 ? -29.916 -45.715 59.610 1.00 39.62 ? 129 THR A N 1 ATOM 991 C CA . THR A 1 129 ? -29.146 -44.727 58.868 1.00 37.75 ? 129 THR A CA 1 ATOM 992 C C . THR A 1 129 ? -29.749 -43.339 59.071 1.00 33.65 ? 129 THR A C 1 ATOM 993 O O . THR A 1 129 ? -30.967 -43.177 59.165 1.00 23.68 ? 129 THR A O 1 ATOM 994 C CB . THR A 1 129 ? -29.092 -45.071 57.364 1.00 38.66 ? 129 THR A CB 1 ATOM 995 O OG1 . THR A 1 129 ? -28.683 -46.436 57.200 1.00 42.03 ? 129 THR A OG1 1 ATOM 996 C CG2 . THR A 1 129 ? -28.117 -44.160 56.631 1.00 33.88 ? 129 THR A CG2 1 ATOM 997 N N . ALA A 1 130 ? -28.884 -42.339 59.154 1.00 32.52 ? 130 ALA A N 1 ATOM 998 C CA . ALA A 1 130 ? -29.336 -40.963 59.274 1.00 34.65 ? 130 ALA A CA 1 ATOM 999 C C . ALA A 1 130 ? -28.762 -40.087 58.149 1.00 28.10 ? 130 ALA A C 1 ATOM 1000 O O . ALA A 1 130 ? -27.551 -39.987 57.985 1.00 25.26 ? 130 ALA A O 1 ATOM 1001 C CB . ALA A 1 130 ? -28.972 -40.407 60.646 1.00 26.04 ? 130 ALA A CB 1 ATOM 1002 N N . SER A 1 131 ? -29.634 -39.466 57.365 1.00 27.18 ? 131 SER A N 1 ATOM 1003 C CA . SER A 1 131 ? -29.185 -38.482 56.391 1.00 19.98 ? 131 SER A CA 1 ATOM 1004 C C . SER A 1 131 ? -29.535 -37.119 56.925 1.00 21.33 ? 131 SER A C 1 ATOM 1005 O O . SER A 1 131 ? -30.666 -36.892 57.336 1.00 22.21 ? 131 SER A O 1 ATOM 1006 C CB . SER A 1 131 ? -29.872 -38.680 55.043 1.00 17.12 ? 131 SER A CB 1 ATOM 1007 O OG . SER A 1 131 ? -29.317 -39.772 54.343 1.00 26.66 ? 131 SER A OG 1 ATOM 1008 N N . VAL A 1 132 ? -28.571 -36.209 56.921 1.00 18.76 ? 132 VAL A N 1 ATOM 1009 C CA . VAL A 1 132 ? -28.848 -34.829 57.280 1.00 17.99 ? 132 VAL A CA 1 ATOM 1010 C C . VAL A 1 132 ? -28.628 -33.988 56.035 1.00 21.95 ? 132 VAL A C 1 ATOM 1011 O O . VAL A 1 132 ? -27.527 -33.949 55.489 1.00 25.23 ? 132 VAL A O 1 ATOM 1012 C CB . VAL A 1 132 ? -27.916 -34.329 58.390 1.00 20.92 ? 132 VAL A CB 1 ATOM 1013 C CG1 . VAL A 1 132 ? -28.361 -32.960 58.862 1.00 23.69 ? 132 VAL A CG1 1 ATOM 1014 C CG2 . VAL A 1 132 ? -27.892 -35.306 59.554 1.00 16.14 ? 132 VAL A CG2 1 ATOM 1015 N N . VAL A 1 133 ? -29.670 -33.318 55.570 1.00 21.51 ? 133 VAL A N 1 ATOM 1016 C CA . VAL A 1 133 ? -29.579 -32.593 54.315 1.00 20.47 ? 133 VAL A CA 1 ATOM 1017 C C . VAL A 1 133 ? -29.492 -31.102 54.572 1.00 18.15 ? 133 VAL A C 1 ATOM 1018 O O . VAL A 1 133 ? -30.228 -30.557 55.381 1.00 17.54 ? 133 VAL A O 1 ATOM 1019 C CB . VAL A 1 133 ? -30.789 -32.917 53.381 1.00 20.86 ? 133 VAL A CB 1 ATOM 1020 C CG1 . VAL A 1 133 ? -30.784 -32.018 52.141 1.00 11.04 ? 133 VAL A CG1 1 ATOM 1021 C CG2 . VAL A 1 133 ? -30.796 -34.398 53.001 1.00 14.05 ? 133 VAL A CG2 1 ATOM 1022 N N . CYS A 1 134 ? -28.577 -30.456 53.868 1.00 16.73 ? 134 CYS A N 1 ATOM 1023 C CA . CYS A 1 134 ? -28.440 -29.016 53.901 1.00 14.51 ? 134 CYS A CA 1 ATOM 1024 C C . CYS A 1 134 ? -28.640 -28.485 52.480 1.00 21.34 ? 134 CYS A C 1 ATOM 1025 O O . CYS A 1 134 ? -27.943 -28.894 51.548 1.00 20.56 ? 134 CYS A O 1 ATOM 1026 C CB . CYS A 1 134 ? -27.048 -28.659 54.410 1.00 22.20 ? 134 CYS A CB 1 ATOM 1027 S SG . CYS A 1 134 ? -26.633 -26.913 54.445 1.00 29.77 ? 134 CYS A SG 1 ATOM 1028 N N . LEU A 1 135 ? -29.599 -27.581 52.316 1.00 17.03 ? 135 LEU A N 1 ATOM 1029 C CA . LEU A 1 135 ? -29.970 -27.089 50.999 1.00 16.12 ? 135 LEU A CA 1 ATOM 1030 C C . LEU A 1 135 ? -29.484 -25.658 50.796 1.00 16.27 ? 135 LEU A C 1 ATOM 1031 O O . LEU A 1 135 ? -29.651 -24.816 51.669 1.00 22.15 ? 135 LEU A O 1 ATOM 1032 C CB . LEU A 1 135 ? -31.490 -27.160 50.835 1.00 12.63 ? 135 LEU A CB 1 ATOM 1033 C CG . LEU A 1 135 ? -32.084 -26.459 49.619 1.00 20.91 ? 135 LEU A CG 1 ATOM 1034 C CD1 . LEU A 1 135 ? -31.787 -27.250 48.364 1.00 20.46 ? 135 LEU A CD1 1 ATOM 1035 C CD2 . LEU A 1 135 ? -33.593 -26.248 49.785 1.00 20.13 ? 135 LEU A CD2 1 ATOM 1036 N N . LEU A 1 136 ? -28.862 -25.392 49.655 1.00 14.07 ? 136 LEU A N 1 ATOM 1037 C CA . LEU A 1 136 ? -28.488 -24.026 49.280 1.00 14.81 ? 136 LEU A CA 1 ATOM 1038 C C . LEU A 1 136 ? -29.298 -23.686 48.040 1.00 19.75 ? 136 LEU A C 1 ATOM 1039 O O . LEU A 1 136 ? -29.122 -24.292 46.980 1.00 16.16 ? 136 LEU A O 1 ATOM 1040 C CB . LEU A 1 136 ? -26.992 -23.913 48.981 1.00 16.68 ? 136 LEU A CB 1 ATOM 1041 C CG . LEU A 1 136 ? -25.963 -23.896 50.126 1.00 22.89 ? 136 LEU A CG 1 ATOM 1042 C CD1 . LEU A 1 136 ? -26.046 -25.123 51.060 1.00 8.72 ? 136 LEU A CD1 1 ATOM 1043 C CD2 . LEU A 1 136 ? -24.557 -23.740 49.544 1.00 11.13 ? 136 LEU A CD2 1 ATOM 1044 N N . ASN A 1 137 ? -30.210 -22.736 48.181 1.00 16.01 ? 137 ASN A N 1 ATOM 1045 C CA . ASN A 1 137 ? -31.201 -22.517 47.141 1.00 17.61 ? 137 ASN A CA 1 ATOM 1046 C C . ASN A 1 137 ? -30.979 -21.248 46.318 1.00 20.83 ? 137 ASN A C 1 ATOM 1047 O O . ASN A 1 137 ? -30.759 -20.159 46.874 1.00 14.73 ? 137 ASN A O 1 ATOM 1048 C CB . ASN A 1 137 ? -32.607 -22.525 47.746 1.00 16.70 ? 137 ASN A CB 1 ATOM 1049 C CG . ASN A 1 137 ? -33.657 -23.044 46.788 1.00 19.36 ? 137 ASN A CG 1 ATOM 1050 O OD1 . ASN A 1 137 ? -33.420 -23.997 46.055 1.00 17.17 ? 137 ASN A OD1 1 ATOM 1051 N ND2 . ASN A 1 137 ? -34.831 -22.417 46.794 1.00 18.71 ? 137 ASN A ND2 1 ATOM 1052 N N . ASN A 1 138 ? -31.020 -21.413 44.992 1.00 17.94 ? 138 ASN A N 1 ATOM 1053 C CA . ASN A 1 138 ? -31.072 -20.283 44.058 1.00 21.97 ? 138 ASN A CA 1 ATOM 1054 C C . ASN A 1 138 ? -29.967 -19.248 44.220 1.00 18.07 ? 138 ASN A C 1 ATOM 1055 O O . ASN A 1 138 ? -30.233 -18.106 44.572 1.00 21.49 ? 138 ASN A O 1 ATOM 1056 C CB . ASN A 1 138 ? -32.432 -19.589 44.142 1.00 14.63 ? 138 ASN A CB 1 ATOM 1057 C CG . ASN A 1 138 ? -33.564 -20.493 43.710 1.00 21.72 ? 138 ASN A CG 1 ATOM 1058 O OD1 . ASN A 1 138 ? -33.373 -21.690 43.464 1.00 17.88 ? 138 ASN A OD1 1 ATOM 1059 N ND2 . ASN A 1 138 ? -34.758 -19.930 43.623 1.00 27.39 ? 138 ASN A ND2 1 ATOM 1060 N N . PHE A 1 139 ? -28.731 -19.647 43.952 1.00 18.46 ? 139 PHE A N 1 ATOM 1061 C CA . PHE A 1 139 ? -27.594 -18.750 44.137 1.00 18.84 ? 139 PHE A CA 1 ATOM 1062 C C . PHE A 1 139 ? -26.748 -18.656 42.872 1.00 17.80 ? 139 PHE A C 1 ATOM 1063 O O . PHE A 1 139 ? -26.907 -19.452 41.943 1.00 13.23 ? 139 PHE A O 1 ATOM 1064 C CB . PHE A 1 139 ? -26.731 -19.209 45.323 1.00 15.19 ? 139 PHE A CB 1 ATOM 1065 C CG . PHE A 1 139 ? -26.176 -20.601 45.173 1.00 17.48 ? 139 PHE A CG 1 ATOM 1066 C CD1 . PHE A 1 139 ? -26.886 -21.699 45.646 1.00 18.06 ? 139 PHE A CD1 1 ATOM 1067 C CD2 . PHE A 1 139 ? -24.945 -20.813 44.553 1.00 14.60 ? 139 PHE A CD2 1 ATOM 1068 C CE1 . PHE A 1 139 ? -26.379 -22.985 45.507 1.00 20.84 ? 139 PHE A CE1 1 ATOM 1069 C CE2 . PHE A 1 139 ? -24.430 -22.084 44.410 1.00 16.55 ? 139 PHE A CE2 1 ATOM 1070 C CZ . PHE A 1 139 ? -25.144 -23.177 44.883 1.00 20.86 ? 139 PHE A CZ 1 ATOM 1071 N N . TYR A 1 140 ? -25.846 -17.676 42.850 1.00 16.95 ? 140 TYR A N 1 ATOM 1072 C CA . TYR A 1 140 ? -24.931 -17.473 41.725 1.00 17.97 ? 140 TYR A CA 1 ATOM 1073 C C . TYR A 1 140 ? -23.724 -16.706 42.225 1.00 17.53 ? 140 TYR A C 1 ATOM 1074 O O . TYR A 1 140 ? -23.880 -15.679 42.884 1.00 22.58 ? 140 TYR A O 1 ATOM 1075 C CB . TYR A 1 140 ? -25.604 -16.709 40.570 1.00 13.76 ? 140 TYR A CB 1 ATOM 1076 C CG . TYR A 1 140 ? -24.728 -16.687 39.333 1.00 20.82 ? 140 TYR A CG 1 ATOM 1077 C CD1 . TYR A 1 140 ? -24.739 -17.748 38.429 1.00 21.31 ? 140 TYR A CD1 1 ATOM 1078 C CD2 . TYR A 1 140 ? -23.859 -15.627 39.088 1.00 21.18 ? 140 TYR A CD2 1 ATOM 1079 C CE1 . TYR A 1 140 ? -23.931 -17.746 37.319 1.00 20.93 ? 140 TYR A CE1 1 ATOM 1080 C CE2 . TYR A 1 140 ? -23.041 -15.616 37.977 1.00 24.23 ? 140 TYR A CE2 1 ATOM 1081 C CZ . TYR A 1 140 ? -23.082 -16.677 37.099 1.00 26.07 ? 140 TYR A CZ 1 ATOM 1082 O OH . TYR A 1 140 ? -22.270 -16.667 35.998 1.00 33.55 ? 140 TYR A OH 1 ATOM 1083 N N . PRO A 1 141 ? -22.515 -17.170 41.887 1.00 20.10 ? 141 PRO A N 1 ATOM 1084 C CA . PRO A 1 141 ? -22.231 -18.233 40.918 1.00 16.11 ? 141 PRO A CA 1 ATOM 1085 C C . PRO A 1 141 ? -22.157 -19.600 41.596 1.00 17.33 ? 141 PRO A C 1 ATOM 1086 O O . PRO A 1 141 ? -22.390 -19.709 42.805 1.00 16.34 ? 141 PRO A O 1 ATOM 1087 C CB . PRO A 1 141 ? -20.853 -17.836 40.404 1.00 17.09 ? 141 PRO A CB 1 ATOM 1088 C CG . PRO A 1 141 ? -20.158 -17.287 41.667 1.00 14.64 ? 141 PRO A CG 1 ATOM 1089 C CD . PRO A 1 141 ? -21.280 -16.644 42.506 1.00 19.60 ? 141 PRO A CD 1 ATOM 1090 N N . ARG A 1 142 ? -21.816 -20.624 40.818 1.00 19.48 ? 142 ARG A N 1 ATOM 1091 C CA . ARG A 1 142 ? -21.839 -22.013 41.268 1.00 17.10 ? 142 ARG A CA 1 ATOM 1092 C C . ARG A 1 142 ? -20.969 -22.301 42.503 1.00 19.42 ? 142 ARG A C 1 ATOM 1093 O O . ARG A 1 142 ? -21.299 -23.160 43.317 1.00 29.61 ? 142 ARG A O 1 ATOM 1094 C CB . ARG A 1 142 ? -21.424 -22.918 40.109 1.00 23.33 ? 142 ARG A CB 1 ATOM 1095 C CG . ARG A 1 142 ? -21.687 -24.407 40.289 1.00 24.30 ? 142 ARG A CG 1 ATOM 1096 C CD . ARG A 1 142 ? -21.082 -25.175 39.106 1.00 27.43 ? 142 ARG A CD 1 ATOM 1097 N NE . ARG A 1 142 ? -21.815 -26.400 38.790 1.00 42.98 ? 142 ARG A NE 1 ATOM 1098 C CZ . ARG A 1 142 ? -21.539 -27.597 39.306 1.00 43.18 ? 142 ARG A CZ 1 ATOM 1099 N NH1 . ARG A 1 142 ? -20.539 -27.740 40.171 1.00 33.32 ? 142 ARG A NH1 1 ATOM 1100 N NH2 . ARG A 1 142 ? -22.265 -28.656 38.960 1.00 45.83 ? 142 ARG A NH2 1 ATOM 1101 N N . GLU A 1 143 ? -19.865 -21.588 42.656 1.00 16.21 ? 143 GLU A N 1 ATOM 1102 C CA . GLU A 1 143 ? -18.949 -21.884 43.755 1.00 19.92 ? 143 GLU A CA 1 ATOM 1103 C C . GLU A 1 143 ? -19.561 -21.602 45.138 1.00 21.10 ? 143 GLU A C 1 ATOM 1104 O O . GLU A 1 143 ? -20.057 -20.504 45.409 1.00 19.95 ? 143 GLU A O 1 ATOM 1105 C CB . GLU A 1 143 ? -17.616 -21.154 43.548 1.00 17.94 ? 143 GLU A CB 1 ATOM 1106 C CG . GLU A 1 143 ? -16.860 -20.769 44.813 1.00 34.11 ? 143 GLU A CG 1 ATOM 1107 C CD . GLU A 1 143 ? -16.194 -21.947 45.520 1.00 31.90 ? 143 GLU A CD 1 ATOM 1108 O OE1 . GLU A 1 143 ? -15.876 -21.802 46.725 1.00 34.03 ? 143 GLU A OE1 1 ATOM 1109 O OE2 . GLU A 1 143 ? -15.985 -23.005 44.884 1.00 25.23 ? 143 GLU A OE2 1 ATOM 1110 N N . ALA A 1 144 ? -19.539 -22.627 45.986 1.00 16.48 ? 144 ALA A N 1 ATOM 1111 C CA . ALA A 1 144 ? -19.996 -22.540 47.374 1.00 20.65 ? 144 ALA A CA 1 ATOM 1112 C C . ALA A 1 144 ? -19.268 -23.554 48.262 1.00 17.00 ? 144 ALA A C 1 ATOM 1113 O O . ALA A 1 144 ? -18.827 -24.601 47.794 1.00 24.85 ? 144 ALA A O 1 ATOM 1114 C CB . ALA A 1 144 ? -21.520 -22.753 47.472 1.00 12.23 ? 144 ALA A CB 1 ATOM 1115 N N . LYS A 1 145 ? -19.142 -23.231 49.541 1.00 19.77 ? 145 LYS A N 1 ATOM 1116 C CA . LYS A 1 145 ? -18.522 -24.126 50.507 1.00 19.89 ? 145 LYS A CA 1 ATOM 1117 C C . LYS A 1 145 ? -19.560 -24.513 51.539 1.00 24.37 ? 145 LYS A C 1 ATOM 1118 O O . LYS A 1 145 ? -20.217 -23.636 52.107 1.00 25.13 ? 145 LYS A O 1 ATOM 1119 C CB . LYS A 1 145 ? -17.372 -23.424 51.221 1.00 20.71 ? 145 LYS A CB 1 ATOM 1120 C CG . LYS A 1 145 ? -16.175 -23.110 50.349 1.00 31.58 ? 145 LYS A CG 1 ATOM 1121 C CD . LYS A 1 145 ? -15.525 -24.377 49.836 1.00 32.72 ? 145 LYS A CD 1 ATOM 1122 C CE . LYS A 1 145 ? -14.309 -24.044 48.989 1.00 32.76 ? 145 LYS A CE 1 ATOM 1123 N NZ . LYS A 1 145 ? -13.504 -25.257 48.709 1.00 45.20 ? 145 LYS A NZ 1 ATOM 1124 N N . VAL A 1 146 ? -19.719 -25.819 51.756 1.00 16.56 ? 146 VAL A N 1 ATOM 1125 C CA . VAL A 1 146 ? -20.515 -26.330 52.858 1.00 18.67 ? 146 VAL A CA 1 ATOM 1126 C C . VAL A 1 146 ? -19.604 -27.074 53.833 1.00 23.34 ? 146 VAL A C 1 ATOM 1127 O O . VAL A 1 146 ? -18.991 -28.090 53.479 1.00 21.19 ? 146 VAL A O 1 ATOM 1128 C CB . VAL A 1 146 ? -21.638 -27.289 52.390 1.00 21.24 ? 146 VAL A CB 1 ATOM 1129 C CG1 . VAL A 1 146 ? -22.329 -27.928 53.597 1.00 18.74 ? 146 VAL A CG1 1 ATOM 1130 C CG2 . VAL A 1 146 ? -22.643 -26.557 51.545 1.00 22.10 ? 146 VAL A CG2 1 ATOM 1131 N N . GLN A 1 147 ? -19.515 -26.561 55.054 1.00 15.73 ? 147 GLN A N 1 ATOM 1132 C CA . GLN A 1 147 ? -18.749 -27.206 56.113 1.00 21.35 ? 147 GLN A CA 1 ATOM 1133 C C . GLN A 1 147 ? -19.678 -27.785 57.186 1.00 19.21 ? 147 GLN A C 1 ATOM 1134 O O . GLN A 1 147 ? -20.550 -27.087 57.712 1.00 16.71 ? 147 GLN A O 1 ATOM 1135 C CB . GLN A 1 147 ? -17.767 -26.204 56.740 1.00 23.68 ? 147 GLN A CB 1 ATOM 1136 C CG . GLN A 1 147 ? -16.916 -26.747 57.873 1.00 27.71 ? 147 GLN A CG 1 ATOM 1137 C CD . GLN A 1 147 ? -15.917 -25.720 58.388 1.00 45.88 ? 147 GLN A CD 1 ATOM 1138 O OE1 . GLN A 1 147 ? -16.088 -25.161 59.480 1.00 37.95 ? 147 GLN A OE1 1 ATOM 1139 N NE2 . GLN A 1 147 ? -14.875 -25.450 57.592 1.00 33.90 ? 147 GLN A NE2 1 ATOM 1140 N N . TRP A 1 148 ? -19.485 -29.063 57.502 1.00 17.82 ? 148 TRP A N 1 ATOM 1141 C CA . TRP A 1 148 ? -20.323 -29.746 58.475 1.00 16.01 ? 148 TRP A CA 1 ATOM 1142 C C . TRP A 1 148 ? -19.656 -29.839 59.838 1.00 21.53 ? 148 TRP A C 1 ATOM 1143 O O . TRP A 1 148 ? -18.488 -30.208 59.946 1.00 19.37 ? 148 TRP A O 1 ATOM 1144 C CB . TRP A 1 148 ? -20.736 -31.144 57.997 1.00 15.26 ? 148 TRP A CB 1 ATOM 1145 C CG . TRP A 1 148 ? -21.820 -31.164 56.959 1.00 17.51 ? 148 TRP A CG 1 ATOM 1146 C CD1 . TRP A 1 148 ? -21.654 -31.248 55.606 1.00 22.34 ? 148 TRP A CD1 1 ATOM 1147 C CD2 . TRP A 1 148 ? -23.239 -31.104 57.186 1.00 19.44 ? 148 TRP A CD2 1 ATOM 1148 N NE1 . TRP A 1 148 ? -22.877 -31.241 54.980 1.00 22.44 ? 148 TRP A NE1 1 ATOM 1149 C CE2 . TRP A 1 148 ? -23.866 -31.158 55.925 1.00 22.97 ? 148 TRP A CE2 1 ATOM 1150 C CE3 . TRP A 1 148 ? -24.037 -31.017 58.333 1.00 19.96 ? 148 TRP A CE3 1 ATOM 1151 C CZ2 . TRP A 1 148 ? -25.256 -31.123 55.775 1.00 23.85 ? 148 TRP A CZ2 1 ATOM 1152 C CZ3 . TRP A 1 148 ? -25.416 -30.987 58.188 1.00 20.15 ? 148 TRP A CZ3 1 ATOM 1153 C CH2 . TRP A 1 148 ? -26.015 -31.037 56.913 1.00 21.95 ? 148 TRP A CH2 1 ATOM 1154 N N . LYS A 1 149 ? -20.416 -29.494 60.875 1.00 17.11 ? 149 LYS A N 1 ATOM 1155 C CA . LYS A 1 149 ? -19.965 -29.652 62.239 1.00 20.59 ? 149 LYS A CA 1 ATOM 1156 C C . LYS A 1 149 ? -20.987 -30.413 63.075 1.00 27.09 ? 149 LYS A C 1 ATOM 1157 O O . LYS A 1 149 ? -22.180 -30.108 63.048 1.00 26.97 ? 149 LYS A O 1 ATOM 1158 C CB . LYS A 1 149 ? -19.647 -28.293 62.870 1.00 24.10 ? 149 LYS A CB 1 ATOM 1159 C CG . LYS A 1 149 ? -18.161 -28.047 63.058 1.00 20.57 ? 149 LYS A CG 1 ATOM 1160 C CD . LYS A 1 149 ? -17.811 -26.588 62.889 1.00 26.27 ? 149 LYS A CD 1 ATOM 1161 C CE . LYS A 1 149 ? -16.300 -26.389 62.825 1.00 34.37 ? 149 LYS A CE 1 ATOM 1162 N NZ . LYS A 1 149 ? -15.933 -24.965 62.518 1.00 52.18 ? 149 LYS A NZ 1 ATOM 1163 N N . VAL A 1 150 ? -20.506 -31.415 63.802 1.00 22.06 ? 150 VAL A N 1 ATOM 1164 C CA . VAL A 1 150 ? -21.316 -32.157 64.751 1.00 21.11 ? 150 VAL A CA 1 ATOM 1165 C C . VAL A 1 150 ? -20.626 -32.042 66.108 1.00 29.26 ? 150 VAL A C 1 ATOM 1166 O O . VAL A 1 150 ? -19.513 -32.564 66.292 1.00 25.26 ? 150 VAL A O 1 ATOM 1167 C CB . VAL A 1 150 ? -21.394 -33.642 64.375 1.00 19.03 ? 150 VAL A CB 1 ATOM 1168 C CG1 . VAL A 1 150 ? -22.190 -34.409 65.424 1.00 20.29 ? 150 VAL A CG1 1 ATOM 1169 C CG2 . VAL A 1 150 ? -21.982 -33.815 62.996 1.00 17.62 ? 150 VAL A CG2 1 ATOM 1170 N N . ASP A 1 151 ? -21.267 -31.347 67.045 1.00 26.72 ? 151 ASP A N 1 ATOM 1171 C CA . ASP A 1 151 ? -20.662 -31.080 68.349 1.00 21.21 ? 151 ASP A CA 1 ATOM 1172 C C . ASP A 1 151 ? -19.287 -30.439 68.160 1.00 23.47 ? 151 ASP A C 1 ATOM 1173 O O . ASP A 1 151 ? -18.290 -30.899 68.706 1.00 27.85 ? 151 ASP A O 1 ATOM 1174 C CB . ASP A 1 151 ? -20.539 -32.373 69.171 1.00 27.49 ? 151 ASP A CB 1 ATOM 1175 C CG . ASP A 1 151 ? -21.891 -32.948 69.600 1.00 28.78 ? 151 ASP A CG 1 ATOM 1176 O OD1 . ASP A 1 151 ? -22.833 -32.177 69.903 1.00 24.26 ? 151 ASP A OD1 1 ATOM 1177 O OD2 . ASP A 1 151 ? -21.999 -34.193 69.649 1.00 31.37 ? 151 ASP A OD2 1 ATOM 1178 N N . ASN A 1 152 ? -19.235 -29.391 67.350 1.00 30.71 ? 152 ASN A N 1 ATOM 1179 C CA . ASN A 1 152 ? -17.977 -28.708 67.019 1.00 30.26 ? 152 ASN A CA 1 ATOM 1180 C C . ASN A 1 152 ? -16.876 -29.549 66.387 1.00 29.10 ? 152 ASN A C 1 ATOM 1181 O O . ASN A 1 152 ? -15.779 -29.046 66.145 1.00 34.05 ? 152 ASN A O 1 ATOM 1182 C CB . ASN A 1 152 ? -17.429 -27.920 68.209 1.00 27.30 ? 152 ASN A CB 1 ATOM 1183 C CG . ASN A 1 152 ? -18.178 -26.626 68.423 1.00 50.04 ? 152 ASN A CG 1 ATOM 1184 O OD1 . ASN A 1 152 ? -18.771 -26.076 67.485 1.00 47.78 ? 152 ASN A OD1 1 ATOM 1185 N ND2 . ASN A 1 152 ? -18.180 -26.138 69.658 1.00 58.52 ? 152 ASN A ND2 1 ATOM 1186 N N . ALA A 1 153 ? -17.153 -30.821 66.119 1.00 25.24 ? 153 ALA A N 1 ATOM 1187 C CA . ALA A 1 153 ? -16.210 -31.622 65.357 1.00 20.43 ? 153 ALA A CA 1 ATOM 1188 C C . ALA A 1 153 ? -16.450 -31.439 63.849 1.00 23.66 ? 153 ALA A C 1 ATOM 1189 O O . ALA A 1 153 ? -17.544 -31.692 63.324 1.00 18.17 ? 153 ALA A O 1 ATOM 1190 C CB . ALA A 1 153 ? -16.298 -33.072 65.750 1.00 23.27 ? 153 ALA A CB 1 ATOM 1191 N N . LEU A 1 154 ? -15.419 -30.958 63.170 1.00 20.00 ? 154 LEU A N 1 ATOM 1192 C CA . LEU A 1 154 ? -15.443 -30.833 61.731 1.00 19.40 ? 154 LEU A CA 1 ATOM 1193 C C . LEU A 1 154 ? -15.679 -32.205 61.096 1.00 21.40 ? 154 LEU A C 1 ATOM 1194 O O . LEU A 1 154 ? -14.983 -33.163 61.406 1.00 24.75 ? 154 LEU A O 1 ATOM 1195 C CB . LEU A 1 154 ? -14.128 -30.235 61.250 1.00 17.61 ? 154 LEU A CB 1 ATOM 1196 C CG . LEU A 1 154 ? -13.910 -30.193 59.737 1.00 25.93 ? 154 LEU A CG 1 ATOM 1197 C CD1 . LEU A 1 154 ? -14.916 -29.280 59.038 1.00 23.52 ? 154 LEU A CD1 1 ATOM 1198 C CD2 . LEU A 1 154 ? -12.477 -29.774 59.439 1.00 20.07 ? 154 LEU A CD2 1 ATOM 1199 N N . GLN A 1 155 ? -16.690 -32.306 60.238 1.00 23.62 ? 155 GLN A N 1 ATOM 1200 C CA . GLN A 1 155 ? -16.965 -33.560 59.547 1.00 22.88 ? 155 GLN A CA 1 ATOM 1201 C C . GLN A 1 155 ? -16.236 -33.554 58.221 1.00 24.12 ? 155 GLN A C 1 ATOM 1202 O O . GLN A 1 155 ? -16.249 -32.551 57.505 1.00 22.45 ? 155 GLN A O 1 ATOM 1203 C CB . GLN A 1 155 ? -18.465 -33.757 59.308 1.00 18.26 ? 155 GLN A CB 1 ATOM 1204 C CG . GLN A 1 155 ? -19.297 -33.829 60.569 1.00 19.30 ? 155 GLN A CG 1 ATOM 1205 C CD . GLN A 1 155 ? -18.872 -34.956 61.478 1.00 22.88 ? 155 GLN A CD 1 ATOM 1206 O OE1 . GLN A 1 155 ? -19.127 -36.128 61.195 1.00 25.41 ? 155 GLN A OE1 1 ATOM 1207 N NE2 . GLN A 1 155 ? -18.224 -34.610 62.585 1.00 21.31 ? 155 GLN A NE2 1 ATOM 1208 N N . SER A 1 156 ? -15.607 -34.677 57.893 1.00 17.98 ? 156 SER A N 1 ATOM 1209 C CA . SER A 1 156 ? -14.922 -34.790 56.624 1.00 19.71 ? 156 SER A CA 1 ATOM 1210 C C . SER A 1 156 ? -15.060 -36.178 56.020 1.00 24.23 ? 156 SER A C 1 ATOM 1211 O O . SER A 1 156 ? -14.971 -37.202 56.725 1.00 22.69 ? 156 SER A O 1 ATOM 1212 C CB . SER A 1 156 ? -13.446 -34.442 56.778 1.00 20.31 ? 156 SER A CB 1 ATOM 1213 O OG . SER A 1 156 ? -12.797 -34.586 55.525 1.00 27.72 ? 156 SER A OG 1 ATOM 1214 N N . GLY A 1 157 ? -15.274 -36.201 54.708 1.00 17.42 ? 157 GLY A N 1 ATOM 1215 C CA . GLY A 1 157 ? -15.377 -37.444 53.973 1.00 23.62 ? 157 GLY A CA 1 ATOM 1216 C C . GLY A 1 157 ? -16.731 -38.126 54.045 1.00 22.77 ? 157 GLY A C 1 ATOM 1217 O O . GLY A 1 157 ? -16.966 -39.088 53.316 1.00 26.85 ? 157 GLY A O 1 ATOM 1218 N N . ASN A 1 158 ? -17.616 -37.643 54.917 1.00 19.92 ? 158 ASN A N 1 ATOM 1219 C CA . ASN A 1 158 ? -18.920 -38.284 55.111 1.00 22.79 ? 158 ASN A CA 1 ATOM 1220 C C . ASN A 1 158 ? -20.115 -37.468 54.605 1.00 27.75 ? 158 ASN A C 1 ATOM 1221 O O . ASN A 1 158 ? -21.239 -37.632 55.074 1.00 31.47 ? 158 ASN A O 1 ATOM 1222 C CB . ASN A 1 158 ? -19.117 -38.743 56.570 1.00 12.73 ? 158 ASN A CB 1 ATOM 1223 C CG . ASN A 1 158 ? -19.007 -37.602 57.566 1.00 21.73 ? 158 ASN A CG 1 ATOM 1224 O OD1 . ASN A 1 158 ? -18.653 -36.473 57.206 1.00 22.61 ? 158 ASN A OD1 1 ATOM 1225 N ND2 . ASN A 1 158 ? -19.290 -37.891 58.828 1.00 22.00 ? 158 ASN A ND2 1 ATOM 1226 N N . SER A 1 159 ? -19.871 -36.594 53.639 1.00 26.29 ? 159 SER A N 1 ATOM 1227 C CA . SER A 1 159 ? -20.956 -35.860 53.017 1.00 23.57 ? 159 SER A CA 1 ATOM 1228 C C . SER A 1 159 ? -20.823 -35.906 51.490 1.00 24.79 ? 159 SER A C 1 ATOM 1229 O O . SER A 1 159 ? -19.719 -36.027 50.958 1.00 27.31 ? 159 SER A O 1 ATOM 1230 C CB . SER A 1 159 ? -20.975 -34.416 53.519 1.00 16.76 ? 159 SER A CB 1 ATOM 1231 O OG . SER A 1 159 ? -19.871 -33.697 53.001 1.00 25.65 ? 159 SER A OG 1 ATOM 1232 N N . GLN A 1 160 ? -21.944 -35.827 50.788 1.00 19.44 ? 160 GLN A N 1 ATOM 1233 C CA . GLN A 1 160 ? -21.910 -35.726 49.340 1.00 22.67 ? 160 GLN A CA 1 ATOM 1234 C C . GLN A 1 160 ? -22.707 -34.518 48.868 1.00 24.00 ? 160 GLN A C 1 ATOM 1235 O O . GLN A 1 160 ? -23.751 -34.166 49.435 1.00 16.31 ? 160 GLN A O 1 ATOM 1236 C CB . GLN A 1 160 ? -22.436 -36.997 48.683 1.00 23.96 ? 160 GLN A CB 1 ATOM 1237 C CG . GLN A 1 160 ? -21.506 -38.206 48.835 1.00 25.01 ? 160 GLN A CG 1 ATOM 1238 C CD . GLN A 1 160 ? -22.092 -39.452 48.194 1.00 29.30 ? 160 GLN A CD 1 ATOM 1239 O OE1 . GLN A 1 160 ? -23.271 -39.763 48.387 1.00 32.25 ? 160 GLN A OE1 1 ATOM 1240 N NE2 . GLN A 1 160 ? -21.285 -40.155 47.404 1.00 24.75 ? 160 GLN A NE2 1 ATOM 1241 N N . GLU A 1 161 ? -22.192 -33.872 47.830 1.00 24.82 ? 161 GLU A N 1 ATOM 1242 C CA . GLU A 1 161 ? -22.818 -32.699 47.269 1.00 18.54 ? 161 GLU A CA 1 ATOM 1243 C C . GLU A 1 161 ? -23.406 -32.989 45.908 1.00 27.05 ? 161 GLU A C 1 ATOM 1244 O O . GLU A 1 161 ? -22.922 -33.854 45.185 1.00 28.31 ? 161 GLU A O 1 ATOM 1245 C CB . GLU A 1 161 ? -21.811 -31.578 47.145 1.00 19.62 ? 161 GLU A CB 1 ATOM 1246 C CG . GLU A 1 161 ? -21.543 -30.855 48.442 1.00 35.75 ? 161 GLU A CG 1 ATOM 1247 C CD . GLU A 1 161 ? -20.680 -29.633 48.224 1.00 42.33 ? 161 GLU A CD 1 ATOM 1248 O OE1 . GLU A 1 161 ? -20.462 -29.262 47.041 1.00 33.77 ? 161 GLU A OE1 1 ATOM 1249 O OE2 . GLU A 1 161 ? -20.220 -29.050 49.231 1.00 37.20 ? 161 GLU A OE2 1 ATOM 1250 N N . SER A 1 162 ? -24.460 -32.256 45.571 1.00 26.19 ? 162 SER A N 1 ATOM 1251 C CA . SER A 1 162 ? -25.064 -32.335 44.258 1.00 15.13 ? 162 SER A CA 1 ATOM 1252 C C . SER A 1 162 ? -25.570 -30.948 43.878 1.00 17.70 ? 162 SER A C 1 ATOM 1253 O O . SER A 1 162 ? -26.164 -30.240 44.700 1.00 22.68 ? 162 SER A O 1 ATOM 1254 C CB . SER A 1 162 ? -26.191 -33.355 44.256 1.00 15.67 ? 162 SER A CB 1 ATOM 1255 O OG . SER A 1 162 ? -26.773 -33.444 42.972 1.00 25.68 ? 162 SER A OG 1 ATOM 1256 N N . VAL A 1 163 ? -25.291 -30.549 42.643 1.00 21.08 ? 163 VAL A N 1 ATOM 1257 C CA . VAL A 1 163 ? -25.634 -29.226 42.146 1.00 16.63 ? 163 VAL A CA 1 ATOM 1258 C C . VAL A 1 163 ? -26.533 -29.372 40.934 1.00 18.71 ? 163 VAL A C 1 ATOM 1259 O O . VAL A 1 163 ? -26.214 -30.115 40.014 1.00 17.91 ? 163 VAL A O 1 ATOM 1260 C CB . VAL A 1 163 ? -24.369 -28.426 41.740 1.00 21.69 ? 163 VAL A CB 1 ATOM 1261 C CG1 . VAL A 1 163 ? -24.749 -27.033 41.231 1.00 22.96 ? 163 VAL A CG1 1 ATOM 1262 C CG2 . VAL A 1 163 ? -23.411 -28.315 42.914 1.00 26.07 ? 163 VAL A CG2 1 ATOM 1263 N N . THR A 1 164 ? -27.667 -28.682 40.936 1.00 18.10 ? 164 THR A N 1 ATOM 1264 C CA . THR A 1 164 ? -28.522 -28.676 39.764 1.00 20.27 ? 164 THR A CA 1 ATOM 1265 C C . THR A 1 164 ? -27.794 -28.009 38.615 1.00 21.89 ? 164 THR A C 1 ATOM 1266 O O . THR A 1 164 ? -26.824 -27.276 38.818 1.00 23.35 ? 164 THR A O 1 ATOM 1267 C CB . THR A 1 164 ? -29.813 -27.881 39.991 1.00 24.67 ? 164 THR A CB 1 ATOM 1268 O OG1 . THR A 1 164 ? -29.504 -26.634 40.625 1.00 20.90 ? 164 THR A OG1 1 ATOM 1269 C CG2 . THR A 1 164 ? -30.782 -28.679 40.863 1.00 21.51 ? 164 THR A CG2 1 ATOM 1270 N N . GLU A 1 165 ? -28.251 -28.269 37.398 1.00 22.43 ? 165 GLU A N 1 ATOM 1271 C CA . GLU A 1 165 ? -27.790 -27.486 36.260 1.00 21.48 ? 165 GLU A CA 1 ATOM 1272 C C . GLU A 1 165 ? -28.399 -26.108 36.394 1.00 20.00 ? 165 GLU A C 1 ATOM 1273 O O . GLU A 1 165 ? -29.254 -25.879 37.241 1.00 21.91 ? 165 GLU A O 1 ATOM 1274 C CB . GLU A 1 165 ? -28.190 -28.134 34.931 1.00 19.51 ? 165 GLU A CB 1 ATOM 1275 C CG . GLU A 1 165 ? -27.419 -29.421 34.604 1.00 26.89 ? 165 GLU A CG 1 ATOM 1276 C CD . GLU A 1 165 ? -25.905 -29.206 34.464 1.00 31.99 ? 165 GLU A CD 1 ATOM 1277 O OE1 . GLU A 1 165 ? -25.455 -28.043 34.339 1.00 37.55 ? 165 GLU A OE1 1 ATOM 1278 O OE2 . GLU A 1 165 ? -25.158 -30.211 34.475 1.00 28.49 ? 165 GLU A OE2 1 ATOM 1279 N N . GLN A 1 166 ? -27.940 -25.179 35.575 1.00 23.16 ? 166 GLN A N 1 ATOM 1280 C CA . GLN A 1 166 ? -28.425 -23.808 35.646 1.00 22.66 ? 166 GLN A CA 1 ATOM 1281 C C . GLN A 1 166 ? -29.915 -23.736 35.329 1.00 19.16 ? 166 GLN A C 1 ATOM 1282 O O . GLN A 1 166 ? -30.416 -24.404 34.424 1.00 23.29 ? 166 GLN A O 1 ATOM 1283 C CB . GLN A 1 166 ? -27.633 -22.912 34.693 1.00 28.49 ? 166 GLN A CB 1 ATOM 1284 C CG . GLN A 1 166 ? -27.273 -21.555 35.259 1.00 27.80 ? 166 GLN A CG 1 ATOM 1285 C CD . GLN A 1 166 ? -26.257 -20.834 34.390 1.00 31.92 ? 166 GLN A CD 1 ATOM 1286 O OE1 . GLN A 1 166 ? -25.665 -21.429 33.485 1.00 32.42 ? 166 GLN A OE1 1 ATOM 1287 N NE2 . GLN A 1 166 ? -26.055 -19.548 34.655 1.00 23.68 ? 166 GLN A NE2 1 ATOM 1288 N N . ASP A 1 167 ? -30.618 -22.914 36.088 1.00 24.03 ? 167 ASP A N 1 ATOM 1289 C CA . ASP A 1 167 ? -32.052 -22.784 35.948 1.00 19.98 ? 167 ASP A CA 1 ATOM 1290 C C . ASP A 1 167 ? -32.363 -21.950 34.712 1.00 22.74 ? 167 ASP A C 1 ATOM 1291 O O . ASP A 1 167 ? -31.727 -20.930 34.472 1.00 24.25 ? 167 ASP A O 1 ATOM 1292 C CB . ASP A 1 167 ? -32.638 -22.142 37.203 1.00 21.44 ? 167 ASP A CB 1 ATOM 1293 C CG . ASP A 1 167 ? -34.139 -22.185 37.222 1.00 29.13 ? 167 ASP A CG 1 ATOM 1294 O OD1 . ASP A 1 167 ? -34.767 -21.205 36.767 1.00 27.99 ? 167 ASP A OD1 1 ATOM 1295 O OD2 . ASP A 1 167 ? -34.687 -23.204 37.698 1.00 43.08 ? 167 ASP A OD2 1 ATOM 1296 N N . SER A 1 168 ? -33.341 -22.381 33.926 1.00 26.09 ? 168 SER A N 1 ATOM 1297 C CA . SER A 1 168 ? -33.615 -21.715 32.658 1.00 24.93 ? 168 SER A CA 1 ATOM 1298 C C . SER A 1 168 ? -34.356 -20.403 32.824 1.00 26.07 ? 168 SER A C 1 ATOM 1299 O O . SER A 1 168 ? -34.447 -19.627 31.876 1.00 26.06 ? 168 SER A O 1 ATOM 1300 C CB . SER A 1 168 ? -34.396 -22.620 31.716 1.00 24.94 ? 168 SER A CB 1 ATOM 1301 O OG . SER A 1 168 ? -35.701 -22.807 32.189 1.00 30.99 ? 168 SER A OG 1 ATOM 1302 N N . LYS A 1 169 ? -34.885 -20.145 34.017 1.00 24.27 ? 169 LYS A N 1 ATOM 1303 C CA . LYS A 1 169 ? -35.617 -18.896 34.234 1.00 18.13 ? 169 LYS A CA 1 ATOM 1304 C C . LYS A 1 169 ? -34.770 -17.822 34.891 1.00 22.01 ? 169 LYS A C 1 ATOM 1305 O O . LYS A 1 169 ? -34.656 -16.737 34.358 1.00 28.11 ? 169 LYS A O 1 ATOM 1306 C CB . LYS A 1 169 ? -36.891 -19.135 35.034 1.00 24.44 ? 169 LYS A CB 1 ATOM 1307 N N . ASP A 1 170 ? -34.170 -18.117 36.044 1.00 29.03 ? 170 ASP A N 1 ATOM 1308 C CA . ASP A 1 170 ? -33.381 -17.108 36.761 1.00 16.92 ? 170 ASP A CA 1 ATOM 1309 C C . ASP A 1 170 ? -31.859 -17.311 36.688 1.00 19.56 ? 170 ASP A C 1 ATOM 1310 O O . ASP A 1 170 ? -31.104 -16.548 37.290 1.00 16.60 ? 170 ASP A O 1 ATOM 1311 C CB . ASP A 1 170 ? -33.847 -16.962 38.226 1.00 14.97 ? 170 ASP A CB 1 ATOM 1312 C CG . ASP A 1 170 ? -33.746 -18.269 39.034 1.00 29.45 ? 170 ASP A CG 1 ATOM 1313 O OD1 . ASP A 1 170 ? -32.749 -19.011 38.885 1.00 25.94 ? 170 ASP A OD1 1 ATOM 1314 O OD2 . ASP A 1 170 ? -34.670 -18.553 39.836 1.00 32.13 ? 170 ASP A OD2 1 ATOM 1315 N N . SER A 1 171 ? -31.420 -18.343 35.972 1.00 14.98 ? 171 SER A N 1 ATOM 1316 C CA . SER A 1 171 ? -29.985 -18.624 35.809 1.00 20.07 ? 171 SER A CA 1 ATOM 1317 C C . SER A 1 171 ? -29.203 -18.941 37.093 1.00 23.65 ? 171 SER A C 1 ATOM 1318 O O . SER A 1 171 ? -27.979 -18.772 37.126 1.00 21.38 ? 171 SER A O 1 ATOM 1319 C CB . SER A 1 171 ? -29.288 -17.467 35.087 1.00 11.06 ? 171 SER A CB 1 ATOM 1320 O OG . SER A 1 171 ? -29.752 -17.353 33.763 1.00 23.01 ? 171 SER A OG 1 ATOM 1321 N N . THR A 1 172 ? -29.886 -19.389 38.145 1.00 15.85 ? 172 THR A N 1 ATOM 1322 C CA . THR A 1 172 ? -29.178 -19.706 39.388 1.00 17.28 ? 172 THR A CA 1 ATOM 1323 C C . THR A 1 172 ? -28.930 -21.207 39.527 1.00 21.08 ? 172 THR A C 1 ATOM 1324 O O . THR A 1 172 ? -29.381 -22.016 38.714 1.00 19.95 ? 172 THR A O 1 ATOM 1325 C CB . THR A 1 172 ? -29.934 -19.214 40.665 1.00 18.27 ? 172 THR A CB 1 ATOM 1326 O OG1 . THR A 1 172 ? -31.088 -20.029 40.891 1.00 19.04 ? 172 THR A OG1 1 ATOM 1327 C CG2 . THR A 1 172 ? -30.357 -17.763 40.548 1.00 17.14 ? 172 THR A CG2 1 ATOM 1328 N N . TYR A 1 173 ? -28.223 -21.566 40.585 1.00 14.52 ? 173 TYR A N 1 ATOM 1329 C CA . TYR A 1 173 ? -27.967 -22.944 40.897 1.00 13.01 ? 173 TYR A CA 1 ATOM 1330 C C . TYR A 1 173 ? -28.549 -23.228 42.253 1.00 17.88 ? 173 TYR A C 1 ATOM 1331 O O . TYR A 1 173 ? -28.738 -22.320 43.066 1.00 20.77 ? 173 TYR A O 1 ATOM 1332 C CB . TYR A 1 173 ? -26.461 -23.194 40.949 1.00 14.50 ? 173 TYR A CB 1 ATOM 1333 C CG . TYR A 1 173 ? -25.736 -22.971 39.647 1.00 18.43 ? 173 TYR A CG 1 ATOM 1334 C CD1 . TYR A 1 173 ? -25.670 -23.977 38.682 1.00 22.71 ? 173 TYR A CD1 1 ATOM 1335 C CD2 . TYR A 1 173 ? -25.112 -21.761 39.383 1.00 19.47 ? 173 TYR A CD2 1 ATOM 1336 C CE1 . TYR A 1 173 ? -25.001 -23.777 37.486 1.00 27.45 ? 173 TYR A CE1 1 ATOM 1337 C CE2 . TYR A 1 173 ? -24.442 -21.549 38.193 1.00 27.39 ? 173 TYR A CE2 1 ATOM 1338 C CZ . TYR A 1 173 ? -24.387 -22.559 37.249 1.00 29.43 ? 173 TYR A CZ 1 ATOM 1339 O OH . TYR A 1 173 ? -23.732 -22.343 36.068 1.00 35.64 ? 173 TYR A OH 1 ATOM 1340 N N . SER A 1 174 ? -28.814 -24.501 42.505 1.00 15.83 ? 174 SER A N 1 ATOM 1341 C CA . SER A 1 174 ? -29.141 -24.939 43.842 1.00 14.29 ? 174 SER A CA 1 ATOM 1342 C C . SER A 1 174 ? -28.253 -26.116 44.182 1.00 19.56 ? 174 SER A C 1 ATOM 1343 O O . SER A 1 174 ? -27.814 -26.841 43.294 1.00 19.45 ? 174 SER A O 1 ATOM 1344 C CB . SER A 1 174 ? -30.626 -25.286 43.965 1.00 14.51 ? 174 SER A CB 1 ATOM 1345 O OG . SER A 1 174 ? -31.390 -24.097 44.086 1.00 14.03 ? 174 SER A OG 1 ATOM 1346 N N . LEU A 1 175 ? -27.980 -26.293 45.471 1.00 22.06 ? 175 LEU A N 1 ATOM 1347 C CA . LEU A 1 175 ? -27.001 -27.270 45.926 1.00 19.73 ? 175 LEU A CA 1 ATOM 1348 C C . LEU A 1 175 ? -27.530 -28.009 47.128 1.00 23.31 ? 175 LEU A C 1 ATOM 1349 O O . LEU A 1 175 ? -28.084 -27.406 48.045 1.00 20.03 ? 175 LEU A O 1 ATOM 1350 C CB . LEU A 1 175 ? -25.693 -26.575 46.318 1.00 19.16 ? 175 LEU A CB 1 ATOM 1351 C CG . LEU A 1 175 ? -24.507 -27.460 46.716 1.00 18.24 ? 175 LEU A CG 1 ATOM 1352 C CD1 . LEU A 1 175 ? -23.207 -26.839 46.250 1.00 16.43 ? 175 LEU A CD1 1 ATOM 1353 C CD2 . LEU A 1 175 ? -24.469 -27.686 48.211 1.00 15.95 ? 175 LEU A CD2 1 ATOM 1354 N N . SER A 1 176 ? -27.328 -29.315 47.133 1.00 20.33 ? 176 SER A N 1 ATOM 1355 C CA . SER A 1 176 ? -27.687 -30.115 48.279 1.00 19.40 ? 176 SER A CA 1 ATOM 1356 C C . SER A 1 176 ? -26.410 -30.726 48.817 1.00 24.35 ? 176 SER A C 1 ATOM 1357 O O . SER A 1 176 ? -25.635 -31.316 48.067 1.00 25.76 ? 176 SER A O 1 ATOM 1358 C CB . SER A 1 176 ? -28.665 -31.234 47.879 1.00 18.81 ? 176 SER A CB 1 ATOM 1359 O OG . SER A 1 176 ? -28.005 -32.292 47.180 1.00 17.56 ? 176 SER A OG 1 ATOM 1360 N N . SER A 1 177 ? -26.191 -30.573 50.112 1.00 18.59 ? 177 SER A N 1 ATOM 1361 C CA . SER A 1 177 ? -25.141 -31.301 50.805 1.00 19.06 ? 177 SER A CA 1 ATOM 1362 C C . SER A 1 177 ? -25.805 -32.282 51.780 1.00 22.74 ? 177 SER A C 1 ATOM 1363 O O . SER A 1 177 ? -26.606 -31.879 52.618 1.00 23.29 ? 177 SER A O 1 ATOM 1364 C CB . SER A 1 177 ? -24.218 -30.329 51.540 1.00 17.36 ? 177 SER A CB 1 ATOM 1365 O OG . SER A 1 177 ? -23.165 -31.001 52.198 1.00 19.53 ? 177 SER A OG 1 ATOM 1366 N N . THR A 1 178 ? -25.491 -33.565 51.640 1.00 19.13 ? 178 THR A N 1 ATOM 1367 C CA . THR A 1 178 ? -26.090 -34.614 52.457 1.00 18.26 ? 178 THR A CA 1 ATOM 1368 C C . THR A 1 178 ? -25.035 -35.293 53.356 1.00 23.05 ? 178 THR A C 1 ATOM 1369 O O . THR A 1 178 ? -24.094 -35.918 52.877 1.00 17.94 ? 178 THR A O 1 ATOM 1370 C CB . THR A 1 178 ? -26.822 -35.656 51.560 1.00 22.60 ? 178 THR A CB 1 ATOM 1371 O OG1 . THR A 1 178 ? -27.755 -34.982 50.701 1.00 27.51 ? 178 THR A OG1 1 ATOM 1372 C CG2 . THR A 1 178 ? -27.562 -36.701 52.390 1.00 16.60 ? 178 THR A CG2 1 ATOM 1373 N N . LEU A 1 179 ? -25.189 -35.130 54.666 1.00 20.99 ? 179 LEU A N 1 ATOM 1374 C CA . LEU A 1 179 ? -24.296 -35.749 55.643 1.00 17.37 ? 179 LEU A CA 1 ATOM 1375 C C . LEU A 1 179 ? -24.891 -37.077 56.076 1.00 18.90 ? 179 LEU A C 1 ATOM 1376 O O . LEU A 1 179 ? -26.039 -37.123 56.496 1.00 21.53 ? 179 LEU A O 1 ATOM 1377 C CB . LEU A 1 179 ? -24.133 -34.837 56.857 1.00 17.43 ? 179 LEU A CB 1 ATOM 1378 C CG . LEU A 1 179 ? -23.299 -35.350 58.034 1.00 16.77 ? 179 LEU A CG 1 ATOM 1379 C CD1 . LEU A 1 179 ? -21.800 -35.278 57.757 1.00 13.81 ? 179 LEU A CD1 1 ATOM 1380 C CD2 . LEU A 1 179 ? -23.658 -34.557 59.281 1.00 13.21 ? 179 LEU A CD2 1 ATOM 1381 N N . THR A 1 180 ? -24.121 -38.154 55.959 1.00 18.00 ? 180 THR A N 1 ATOM 1382 C CA . THR A 1 180 ? -24.610 -39.496 56.284 1.00 21.39 ? 180 THR A CA 1 ATOM 1383 C C . THR A 1 180 ? -23.883 -40.176 57.457 1.00 23.88 ? 180 THR A C 1 ATOM 1384 O O . THR A 1 180 ? -22.662 -40.291 57.460 1.00 34.25 ? 180 THR A O 1 ATOM 1385 C CB . THR A 1 180 ? -24.593 -40.409 55.047 1.00 21.39 ? 180 THR A CB 1 ATOM 1386 O OG1 . THR A 1 180 ? -25.513 -39.886 54.095 1.00 33.66 ? 180 THR A OG1 1 ATOM 1387 C CG2 . THR A 1 180 ? -25.036 -41.812 55.407 1.00 29.06 ? 180 THR A CG2 1 ATOM 1388 N N . LEU A 1 181 ? -24.659 -40.603 58.451 1.00 29.73 ? 181 LEU A N 1 ATOM 1389 C CA . LEU A 1 181 ? -24.153 -41.235 59.669 1.00 32.45 ? 181 LEU A CA 1 ATOM 1390 C C . LEU A 1 181 ? -24.945 -42.494 59.957 1.00 36.47 ? 181 LEU A C 1 ATOM 1391 O O . LEU A 1 181 ? -26.097 -42.625 59.536 1.00 31.66 ? 181 LEU A O 1 ATOM 1392 C CB . LEU A 1 181 ? -24.355 -40.330 60.881 1.00 31.68 ? 181 LEU A CB 1 ATOM 1393 C CG . LEU A 1 181 ? -24.031 -38.846 60.855 1.00 35.04 ? 181 LEU A CG 1 ATOM 1394 C CD1 . LEU A 1 181 ? -24.849 -38.185 61.928 1.00 38.30 ? 181 LEU A CD1 1 ATOM 1395 C CD2 . LEU A 1 181 ? -22.559 -38.636 61.128 1.00 44.38 ? 181 LEU A CD2 1 ATOM 1396 N N . SER A 1 182 ? -24.341 -43.400 60.716 1.00 39.24 ? 182 SER A N 1 ATOM 1397 C CA . SER A 1 182 ? -25.068 -44.540 61.249 1.00 40.04 ? 182 SER A CA 1 ATOM 1398 C C . SER A 1 182 ? -26.104 -44.009 62.238 1.00 33.39 ? 182 SER A C 1 ATOM 1399 O O . SER A 1 182 ? -25.964 -42.892 62.735 1.00 35.27 ? 182 SER A O 1 ATOM 1400 C CB . SER A 1 182 ? -24.099 -45.502 61.934 1.00 35.90 ? 182 SER A CB 1 ATOM 1401 O OG . SER A 1 182 ? -23.491 -44.895 63.058 1.00 35.57 ? 182 SER A OG 1 ATOM 1402 N N . LYS A 1 183 ? -27.154 -44.776 62.509 1.00 31.07 ? 183 LYS A N 1 ATOM 1403 C CA . LYS A 1 183 ? -28.116 -44.323 63.503 1.00 31.04 ? 183 LYS A CA 1 ATOM 1404 C C . LYS A 1 183 ? -27.429 -44.211 64.853 1.00 31.80 ? 183 LYS A C 1 ATOM 1405 O O . LYS A 1 183 ? -27.692 -43.275 65.611 1.00 30.56 ? 183 LYS A O 1 ATOM 1406 C CB . LYS A 1 183 ? -29.326 -45.250 63.614 1.00 26.03 ? 183 LYS A CB 1 ATOM 1407 C CG . LYS A 1 183 ? -30.349 -44.748 64.631 1.00 29.93 ? 183 LYS A CG 1 ATOM 1408 C CD . LYS A 1 183 ? -31.457 -45.753 64.915 1.00 35.10 ? 183 LYS A CD 1 ATOM 1409 C CE . LYS A 1 183 ? -32.327 -45.276 66.082 1.00 48.71 ? 183 LYS A CE 1 ATOM 1410 N NZ . LYS A 1 183 ? -33.223 -46.349 66.635 1.00 54.71 ? 183 LYS A NZ 1 ATOM 1411 N N . ALA A 1 184 ? -26.539 -45.163 65.142 1.00 39.02 ? 184 ALA A N 1 ATOM 1412 C CA . ALA A 1 184 ? -25.857 -45.199 66.439 1.00 40.06 ? 184 ALA A CA 1 ATOM 1413 C C . ALA A 1 184 ? -25.072 -43.916 66.655 1.00 35.04 ? 184 ALA A C 1 ATOM 1414 O O . ALA A 1 184 ? -25.244 -43.262 67.680 1.00 29.38 ? 184 ALA A O 1 ATOM 1415 C CB . ALA A 1 184 ? -24.942 -46.427 66.565 1.00 28.36 ? 184 ALA A CB 1 ATOM 1416 N N . ASP A 1 185 ? -24.239 -43.563 65.669 1.00 34.89 ? 185 ASP A N 1 ATOM 1417 C CA . ASP A 1 185 ? -23.450 -42.330 65.681 1.00 29.91 ? 185 ASP A CA 1 ATOM 1418 C C . ASP A 1 185 ? -24.338 -41.104 65.835 1.00 32.78 ? 185 ASP A C 1 ATOM 1419 O O . ASP A 1 185 ? -24.063 -40.235 66.663 1.00 31.53 ? 185 ASP A O 1 ATOM 1420 C CB . ASP A 1 185 ? -22.615 -42.184 64.398 1.00 40.38 ? 185 ASP A CB 1 ATOM 1421 C CG . ASP A 1 185 ? -21.337 -43.034 64.417 1.00 47.82 ? 185 ASP A CG 1 ATOM 1422 O OD1 . ASP A 1 185 ? -21.056 -43.663 65.464 1.00 49.32 ? 185 ASP A OD1 1 ATOM 1423 O OD2 . ASP A 1 185 ? -20.605 -43.063 63.397 1.00 42.71 ? 185 ASP A OD2 1 ATOM 1424 N N . TYR A 1 186 ? -25.396 -41.036 65.029 1.00 31.96 ? 186 TYR A N 1 ATOM 1425 C CA . TYR A 1 186 ? -26.310 -39.909 65.067 1.00 20.50 ? 186 TYR A CA 1 ATOM 1426 C C . TYR A 1 186 ? -26.849 -39.740 66.467 1.00 25.17 ? 186 TYR A C 1 ATOM 1427 O O . TYR A 1 186 ? -26.887 -38.631 66.992 1.00 28.48 ? 186 TYR A O 1 ATOM 1428 C CB . TYR A 1 186 ? -27.462 -40.080 64.063 1.00 28.20 ? 186 TYR A CB 1 ATOM 1429 C CG . TYR A 1 186 ? -28.483 -38.960 64.133 1.00 24.15 ? 186 TYR A CG 1 ATOM 1430 C CD1 . TYR A 1 186 ? -28.185 -37.695 63.647 1.00 24.08 ? 186 TYR A CD1 1 ATOM 1431 C CD2 . TYR A 1 186 ? -29.738 -39.160 64.695 1.00 27.60 ? 186 TYR A CD2 1 ATOM 1432 C CE1 . TYR A 1 186 ? -29.101 -36.666 63.717 1.00 25.71 ? 186 TYR A CE1 1 ATOM 1433 C CE2 . TYR A 1 186 ? -30.664 -38.133 64.761 1.00 22.47 ? 186 TYR A CE2 1 ATOM 1434 C CZ . TYR A 1 186 ? -30.338 -36.891 64.279 1.00 25.57 ? 186 TYR A CZ 1 ATOM 1435 O OH . TYR A 1 186 ? -31.247 -35.864 64.356 1.00 16.51 ? 186 TYR A OH 1 ATOM 1436 N N . GLU A 1 187 ? -27.252 -40.846 67.082 1.00 30.82 ? 187 GLU A N 1 ATOM 1437 C CA . GLU A 1 187 ? -27.825 -40.784 68.426 1.00 33.15 ? 187 GLU A CA 1 ATOM 1438 C C . GLU A 1 187 ? -26.831 -40.312 69.503 1.00 29.37 ? 187 GLU A C 1 ATOM 1439 O O . GLU A 1 187 ? -27.220 -39.674 70.480 1.00 27.44 ? 187 GLU A O 1 ATOM 1440 C CB . GLU A 1 187 ? -28.477 -42.119 68.811 1.00 26.88 ? 187 GLU A CB 1 ATOM 1441 C CG . GLU A 1 187 ? -29.738 -42.478 68.004 1.00 30.36 ? 187 GLU A CG 1 ATOM 1442 C CD . GLU A 1 187 ? -30.863 -41.450 68.129 1.00 36.86 ? 187 GLU A CD 1 ATOM 1443 O OE1 . GLU A 1 187 ? -30.794 -40.584 69.034 1.00 36.41 ? 187 GLU A OE1 1 ATOM 1444 O OE2 . GLU A 1 187 ? -31.821 -41.505 67.312 1.00 31.44 ? 187 GLU A OE2 1 ATOM 1445 N N . LYS A 1 188 ? -25.549 -40.599 69.308 1.00 28.98 ? 188 LYS A N 1 ATOM 1446 C CA . LYS A 1 188 ? -24.531 -40.206 70.286 1.00 34.14 ? 188 LYS A CA 1 ATOM 1447 C C . LYS A 1 188 ? -24.153 -38.721 70.290 1.00 36.76 ? 188 LYS A C 1 ATOM 1448 O O . LYS A 1 188 ? -23.254 -38.326 71.028 1.00 37.84 ? 188 LYS A O 1 ATOM 1449 C CB . LYS A 1 188 ? -23.256 -41.032 70.102 1.00 34.09 ? 188 LYS A CB 1 ATOM 1450 C CG . LYS A 1 188 ? -23.403 -42.507 70.392 1.00 32.09 ? 188 LYS A CG 1 ATOM 1451 C CD . LYS A 1 188 ? -22.085 -43.211 70.136 1.00 36.98 ? 188 LYS A CD 1 ATOM 1452 C CE . LYS A 1 188 ? -22.167 -44.709 70.400 1.00 48.99 ? 188 LYS A CE 1 ATOM 1453 N NZ . LYS A 1 188 ? -22.197 -45.520 69.136 1.00 46.11 ? 188 LYS A NZ 1 ATOM 1454 N N . HIS A 1 189 ? -24.822 -37.900 69.482 1.00 34.95 ? 189 HIS A N 1 ATOM 1455 C CA . HIS A 1 189 ? -24.440 -36.494 69.367 1.00 25.04 ? 189 HIS A CA 1 ATOM 1456 C C . HIS A 1 189 ? -25.638 -35.563 69.407 1.00 31.54 ? 189 HIS A C 1 ATOM 1457 O O . HIS A 1 189 ? -26.773 -36.007 69.271 1.00 33.83 ? 189 HIS A O 1 ATOM 1458 C CB . HIS A 1 189 ? -23.640 -36.273 68.091 1.00 28.59 ? 189 HIS A CB 1 ATOM 1459 C CG . HIS A 1 189 ? -22.353 -37.041 68.038 1.00 34.79 ? 189 HIS A CG 1 ATOM 1460 N ND1 . HIS A 1 189 ? -22.173 -38.142 67.225 1.00 37.79 ? 189 HIS A ND1 1 ATOM 1461 C CD2 . HIS A 1 189 ? -21.177 -36.860 68.687 1.00 29.46 ? 189 HIS A CD2 1 ATOM 1462 C CE1 . HIS A 1 189 ? -20.944 -38.605 67.377 1.00 37.42 ? 189 HIS A CE1 1 ATOM 1463 N NE2 . HIS A 1 189 ? -20.320 -37.846 68.258 1.00 37.00 ? 189 HIS A NE2 1 ATOM 1464 N N . LYS A 1 190 ? -25.400 -34.266 69.583 1.00 29.61 ? 190 LYS A N 1 ATOM 1465 C CA . LYS A 1 190 ? -26.528 -33.350 69.711 1.00 32.66 ? 190 LYS A CA 1 ATOM 1466 C C . LYS A 1 190 ? -26.642 -32.241 68.652 1.00 30.69 ? 190 LYS A C 1 ATOM 1467 O O . LYS A 1 190 ? -27.709 -32.044 68.072 1.00 32.74 ? 190 LYS A O 1 ATOM 1468 C CB . LYS A 1 190 ? -26.570 -32.738 71.115 1.00 30.44 ? 190 LYS A CB 1 ATOM 1469 C CG . LYS A 1 190 ? -27.862 -31.974 71.407 1.00 30.28 ? 190 LYS A CG 1 ATOM 1470 C CD . LYS A 1 190 ? -27.771 -31.194 72.717 1.00 43.93 ? 190 LYS A CD 1 ATOM 1471 C CE . LYS A 1 190 ? -28.685 -29.978 72.707 1.00 47.80 ? 190 LYS A CE 1 ATOM 1472 N NZ . LYS A 1 190 ? -28.150 -28.892 73.572 1.00 47.27 ? 190 LYS A NZ 1 ATOM 1473 N N . VAL A 1 191 ? -25.565 -31.500 68.426 1.00 28.46 ? 191 VAL A N 1 ATOM 1474 C CA . VAL A 1 191 ? -25.652 -30.284 67.617 1.00 27.23 ? 191 VAL A CA 1 ATOM 1475 C C . VAL A 1 191 ? -25.123 -30.511 66.202 1.00 26.51 ? 191 VAL A C 1 ATOM 1476 O O . VAL A 1 191 ? -23.934 -30.767 66.008 1.00 27.23 ? 191 VAL A O 1 ATOM 1477 C CB . VAL A 1 191 ? -24.930 -29.091 68.305 1.00 22.91 ? 191 VAL A CB 1 ATOM 1478 C CG1 . VAL A 1 191 ? -24.756 -27.927 67.361 1.00 15.49 ? 191 VAL A CG1 1 ATOM 1479 C CG2 . VAL A 1 191 ? -25.710 -28.649 69.527 1.00 25.96 ? 191 VAL A CG2 1 ATOM 1480 N N . TYR A 1 192 ? -26.024 -30.415 65.227 1.00 25.30 ? 192 TYR A N 1 ATOM 1481 C CA . TYR A 1 192 ? -25.711 -30.624 63.808 1.00 23.83 ? 192 TYR A CA 1 ATOM 1482 C C . TYR A 1 192 ? -25.774 -29.311 63.062 1.00 22.76 ? 192 TYR A C 1 ATOM 1483 O O . TYR A 1 192 ? -26.825 -28.690 62.975 1.00 24.17 ? 192 TYR A O 1 ATOM 1484 C CB . TYR A 1 192 ? -26.677 -31.637 63.188 1.00 21.59 ? 192 TYR A CB 1 ATOM 1485 C CG . TYR A 1 192 ? -26.490 -33.017 63.773 1.00 25.31 ? 192 TYR A CG 1 ATOM 1486 C CD1 . TYR A 1 192 ? -25.656 -33.936 63.162 1.00 20.60 ? 192 TYR A CD1 1 ATOM 1487 C CD2 . TYR A 1 192 ? -27.108 -33.382 64.960 1.00 28.18 ? 192 TYR A CD2 1 ATOM 1488 C CE1 . TYR A 1 192 ? -25.461 -35.186 63.695 1.00 25.37 ? 192 TYR A CE1 1 ATOM 1489 C CE2 . TYR A 1 192 ? -26.913 -34.635 65.513 1.00 24.32 ? 192 TYR A CE2 1 ATOM 1490 C CZ . TYR A 1 192 ? -26.087 -35.527 64.874 1.00 28.12 ? 192 TYR A CZ 1 ATOM 1491 O OH . TYR A 1 192 ? -25.883 -36.766 65.409 1.00 26.77 ? 192 TYR A OH 1 ATOM 1492 N N . ALA A 1 193 ? -24.634 -28.871 62.548 1.00 23.70 ? 193 ALA A N 1 ATOM 1493 C CA . ALA A 1 193 ? -24.570 -27.584 61.878 1.00 23.04 ? 193 ALA A CA 1 ATOM 1494 C C . ALA A 1 193 ? -23.900 -27.680 60.523 1.00 21.11 ? 193 ALA A C 1 ATOM 1495 O O . ALA A 1 193 ? -22.837 -28.276 60.376 1.00 27.14 ? 193 ALA A O 1 ATOM 1496 C CB . ALA A 1 193 ? -23.867 -26.553 62.749 1.00 22.73 ? 193 ALA A CB 1 ATOM 1497 N N . CYS A 1 194 ? -24.546 -27.106 59.522 1.00 15.78 ? 194 CYS A N 1 ATOM 1498 C CA . CYS A 1 194 ? -23.885 -26.932 58.264 1.00 22.29 ? 194 CYS A CA 1 ATOM 1499 C C . CYS A 1 194 ? -23.643 -25.446 58.117 1.00 22.46 ? 194 CYS A C 1 ATOM 1500 O O . CYS A 1 194 ? -24.496 -24.621 58.466 1.00 24.84 ? 194 CYS A O 1 ATOM 1501 C CB . CYS A 1 194 ? -24.676 -27.541 57.099 1.00 28.83 ? 194 CYS A CB 1 ATOM 1502 S SG . CYS A 1 194 ? -25.905 -26.495 56.315 1.00 37.35 ? 194 CYS A SG 1 ATOM 1503 N N . GLU A 1 195 ? -22.443 -25.127 57.653 1.00 17.44 ? 195 GLU A N 1 ATOM 1504 C CA . GLU A 1 195 ? -22.005 -23.762 57.490 1.00 21.79 ? 195 GLU A CA 1 ATOM 1505 C C . GLU A 1 195 ? -21.760 -23.489 56.013 1.00 28.05 ? 195 GLU A C 1 ATOM 1506 O O . GLU A 1 195 ? -21.098 -24.275 55.317 1.00 21.76 ? 195 GLU A O 1 ATOM 1507 C CB . GLU A 1 195 ? -20.718 -23.531 58.266 1.00 28.52 ? 195 GLU A CB 1 ATOM 1508 C CG . GLU A 1 195 ? -20.598 -22.130 58.799 1.00 28.01 ? 195 GLU A CG 1 ATOM 1509 C CD . GLU A 1 195 ? -19.169 -21.704 58.945 1.00 32.83 ? 195 GLU A CD 1 ATOM 1510 O OE1 . GLU A 1 195 ? -18.377 -22.012 58.020 1.00 39.63 ? 195 GLU A OE1 1 ATOM 1511 O OE2 . GLU A 1 195 ? -18.842 -21.076 59.976 1.00 29.55 ? 195 GLU A OE2 1 ATOM 1512 N N . VAL A 1 196 ? -22.296 -22.370 55.543 1.00 20.85 ? 196 VAL A N 1 ATOM 1513 C CA . VAL A 1 196 ? -22.283 -22.077 54.128 1.00 18.85 ? 196 VAL A CA 1 ATOM 1514 C C . VAL A 1 196 ? -21.503 -20.805 53.840 1.00 20.51 ? 196 VAL A C 1 ATOM 1515 O O . VAL A 1 196 ? -21.678 -19.786 54.500 1.00 23.45 ? 196 VAL A O 1 ATOM 1516 C CB . VAL A 1 196 ? -23.717 -21.983 53.595 1.00 22.90 ? 196 VAL A CB 1 ATOM 1517 C CG1 . VAL A 1 196 ? -23.751 -21.392 52.183 1.00 11.20 ? 196 VAL A CG1 1 ATOM 1518 C CG2 . VAL A 1 196 ? -24.387 -23.367 53.682 1.00 18.50 ? 196 VAL A CG2 1 ATOM 1519 N N . THR A 1 197 ? -20.621 -20.890 52.857 1.00 19.27 ? 197 THR A N 1 ATOM 1520 C CA . THR A 1 197 ? -19.829 -19.762 52.435 1.00 23.20 ? 197 THR A CA 1 ATOM 1521 C C . THR A 1 197 ? -20.113 -19.501 50.971 1.00 23.20 ? 197 THR A C 1 ATOM 1522 O O . THR A 1 197 ? -20.115 -20.424 50.153 1.00 26.56 ? 197 THR A O 1 ATOM 1523 C CB . THR A 1 197 ? -18.316 -20.048 52.602 1.00 26.66 ? 197 THR A CB 1 ATOM 1524 O OG1 . THR A 1 197 ? -18.010 -20.210 53.996 1.00 27.24 ? 197 THR A OG1 1 ATOM 1525 C CG2 . THR A 1 197 ? -17.485 -18.907 52.010 1.00 20.00 ? 197 THR A CG2 1 ATOM 1526 N N . HIS A 1 198 ? -20.347 -18.243 50.632 1.00 18.15 ? 198 HIS A N 1 ATOM 1527 C CA . HIS A 1 198 ? -20.621 -17.887 49.252 1.00 18.51 ? 198 HIS A CA 1 ATOM 1528 C C . HIS A 1 198 ? -20.271 -16.439 49.013 1.00 16.45 ? 198 HIS A C 1 ATOM 1529 O O . HIS A 1 198 ? -20.355 -15.619 49.925 1.00 16.64 ? 198 HIS A O 1 ATOM 1530 C CB . HIS A 1 198 ? -22.099 -18.109 48.933 1.00 16.26 ? 198 HIS A CB 1 ATOM 1531 C CG . HIS A 1 198 ? -22.436 -17.904 47.494 1.00 13.08 ? 198 HIS A CG 1 ATOM 1532 N ND1 . HIS A 1 198 ? -22.792 -16.678 46.987 1.00 11.75 ? 198 HIS A ND1 1 ATOM 1533 C CD2 . HIS A 1 198 ? -22.457 -18.765 46.453 1.00 13.89 ? 198 HIS A CD2 1 ATOM 1534 C CE1 . HIS A 1 198 ? -23.028 -16.795 45.695 1.00 14.36 ? 198 HIS A CE1 1 ATOM 1535 N NE2 . HIS A 1 198 ? -22.835 -18.053 45.345 1.00 10.68 ? 198 HIS A NE2 1 ATOM 1536 N N . GLN A 1 199 ? -19.893 -16.129 47.779 1.00 17.63 ? 199 GLN A N 1 ATOM 1537 C CA . GLN A 1 199 ? -19.549 -14.759 47.376 1.00 22.45 ? 199 GLN A CA 1 ATOM 1538 C C . GLN A 1 199 ? -20.619 -13.716 47.744 1.00 23.16 ? 199 GLN A C 1 ATOM 1539 O O . GLN A 1 199 ? -20.284 -12.582 48.074 1.00 22.37 ? 199 GLN A O 1 ATOM 1540 C CB . GLN A 1 199 ? -19.269 -14.716 45.865 1.00 21.47 ? 199 GLN A CB 1 ATOM 1541 C CG . GLN A 1 199 ? -18.817 -13.374 45.315 1.00 20.00 ? 199 GLN A CG 1 ATOM 1542 C CD . GLN A 1 199 ? -18.451 -13.433 43.830 1.00 29.29 ? 199 GLN A CD 1 ATOM 1543 O OE1 . GLN A 1 199 ? -18.358 -14.510 43.234 1.00 29.28 ? 199 GLN A OE1 1 ATOM 1544 N NE2 . GLN A 1 199 ? -18.241 -12.266 43.228 1.00 33.89 ? 199 GLN A NE2 1 ATOM 1545 N N . GLY A 1 200 ? -21.896 -14.104 47.689 1.00 15.28 ? 200 GLY A N 1 ATOM 1546 C CA . GLY A 1 200 ? -22.990 -13.203 47.999 1.00 17.12 ? 200 GLY A CA 1 ATOM 1547 C C . GLY A 1 200 ? -23.285 -13.015 49.481 1.00 24.30 ? 200 GLY A C 1 ATOM 1548 O O . GLY A 1 200 ? -24.107 -12.177 49.862 1.00 27.97 ? 200 GLY A O 1 ATOM 1549 N N . LEU A 1 201 ? -22.626 -13.799 50.324 1.00 18.63 ? 201 LEU A N 1 ATOM 1550 C CA . LEU A 1 201 ? -22.793 -13.655 51.757 1.00 18.71 ? 201 LEU A CA 1 ATOM 1551 C C . LEU A 1 201 ? -21.674 -12.793 52.316 1.00 23.95 ? 201 LEU A C 1 ATOM 1552 O O . LEU A 1 201 ? -20.512 -12.939 51.938 1.00 26.19 ? 201 LEU A O 1 ATOM 1553 C CB . LEU A 1 201 ? -22.802 -15.019 52.429 1.00 18.11 ? 201 LEU A CB 1 ATOM 1554 C CG . LEU A 1 201 ? -23.976 -15.892 51.983 1.00 18.52 ? 201 LEU A CG 1 ATOM 1555 C CD1 . LEU A 1 201 ? -23.853 -17.256 52.611 1.00 17.46 ? 201 LEU A CD1 1 ATOM 1556 C CD2 . LEU A 1 201 ? -25.285 -15.235 52.361 1.00 11.13 ? 201 LEU A CD2 1 ATOM 1557 N N . SER A 1 202 ? -22.021 -11.869 53.200 1.00 25.02 ? 202 SER A N 1 ATOM 1558 C CA . SER A 1 202 ? -20.997 -10.999 53.751 1.00 31.56 ? 202 SER A CA 1 ATOM 1559 C C . SER A 1 202 ? -20.275 -11.706 54.897 1.00 24.83 ? 202 SER A C 1 ATOM 1560 O O . SER A 1 202 ? -19.210 -11.281 55.315 1.00 41.62 ? 202 SER A O 1 ATOM 1561 C CB . SER A 1 202 ? -21.571 -9.640 54.164 1.00 22.82 ? 202 SER A CB 1 ATOM 1562 O OG . SER A 1 202 ? -22.442 -9.756 55.264 1.00 29.77 ? 202 SER A OG 1 ATOM 1563 N N . SER A 1 203 ? -20.863 -12.785 55.398 1.00 20.75 ? 203 SER A N 1 ATOM 1564 C CA . SER A 1 203 ? -20.180 -13.681 56.329 1.00 27.39 ? 203 SER A CA 1 ATOM 1565 C C . SER A 1 203 ? -20.884 -15.041 56.268 1.00 25.35 ? 203 SER A C 1 ATOM 1566 O O . SER A 1 203 ? -22.014 -15.112 55.796 1.00 24.35 ? 203 SER A O 1 ATOM 1567 C CB . SER A 1 203 ? -20.133 -13.104 57.753 1.00 24.28 ? 203 SER A CB 1 ATOM 1568 O OG . SER A 1 203 ? -21.411 -12.756 58.222 1.00 28.83 ? 203 SER A OG 1 ATOM 1569 N N . PRO A 1 204 ? -20.208 -16.129 56.698 1.00 30.61 ? 204 PRO A N 1 ATOM 1570 C CA . PRO A 1 204 ? -20.825 -17.458 56.554 1.00 22.81 ? 204 PRO A CA 1 ATOM 1571 C C . PRO A 1 204 ? -22.167 -17.566 57.271 1.00 22.53 ? 204 PRO A C 1 ATOM 1572 O O . PRO A 1 204 ? -22.355 -16.968 58.324 1.00 26.00 ? 204 PRO A O 1 ATOM 1573 C CB . PRO A 1 204 ? -19.799 -18.394 57.195 1.00 25.24 ? 204 PRO A CB 1 ATOM 1574 C CG . PRO A 1 204 ? -18.500 -17.676 57.071 1.00 27.31 ? 204 PRO A CG 1 ATOM 1575 C CD . PRO A 1 204 ? -18.822 -16.216 57.201 1.00 24.95 ? 204 PRO A CD 1 ATOM 1576 N N . VAL A 1 205 ? -23.095 -18.301 56.677 1.00 18.90 ? 205 VAL A N 1 ATOM 1577 C CA . VAL A 1 205 ? -24.403 -18.523 57.274 1.00 18.12 ? 205 VAL A CA 1 ATOM 1578 C C . VAL A 1 205 ? -24.443 -19.931 57.839 1.00 15.92 ? 205 VAL A C 1 ATOM 1579 O O . VAL A 1 205 ? -24.058 -20.887 57.173 1.00 23.54 ? 205 VAL A O 1 ATOM 1580 C CB . VAL A 1 205 ? -25.531 -18.383 56.229 1.00 15.10 ? 205 VAL A CB 1 ATOM 1581 C CG1 . VAL A 1 205 ? -26.853 -18.749 56.829 1.00 20.44 ? 205 VAL A CG1 1 ATOM 1582 C CG2 . VAL A 1 205 ? -25.576 -16.972 55.687 1.00 20.73 ? 205 VAL A CG2 1 ATOM 1583 N N . THR A 1 206 ? -24.900 -20.059 59.073 1.00 17.37 ? 206 THR A N 1 ATOM 1584 C CA . THR A 1 206 ? -24.951 -21.349 59.723 1.00 19.61 ? 206 THR A CA 1 ATOM 1585 C C . THR A 1 206 ? -26.406 -21.718 59.994 1.00 21.55 ? 206 THR A C 1 ATOM 1586 O O . THR A 1 206 ? -27.157 -20.933 60.555 1.00 24.56 ? 206 THR A O 1 ATOM 1587 C CB . THR A 1 206 ? -24.172 -21.336 61.055 1.00 18.83 ? 206 THR A CB 1 ATOM 1588 O OG1 . THR A 1 206 ? -22.792 -21.070 60.803 1.00 17.57 ? 206 THR A OG1 1 ATOM 1589 C CG2 . THR A 1 206 ? -24.276 -22.689 61.745 1.00 21.10 ? 206 THR A CG2 1 ATOM 1590 N N . LYS A 1 207 ? -26.799 -22.910 59.598 1.00 19.41 ? 207 LYS A N 1 ATOM 1591 C CA . LYS A 1 207 ? -28.084 -23.454 59.909 1.00 20.00 ? 207 LYS A CA 1 ATOM 1592 C C . LYS A 1 207 ? -27.873 -24.700 60.731 1.00 29.00 ? 207 LYS A C 1 ATOM 1593 O O . LYS A 1 207 ? -27.040 -25.473 60.450 1.00 23.74 ? 207 LYS A O 1 ATOM 1594 C CB . LYS A 1 207 ? -28.843 -23.777 58.645 1.00 17.25 ? 207 LYS A CB 1 ATOM 1595 C CG . LYS A 1 207 ? -29.600 -22.645 58.013 1.00 20.33 ? 207 LYS A CG 1 ATOM 1596 C CD . LYS A 1 207 ? -30.196 -21.737 59.048 1.00 24.19 ? 207 LYS A CD 1 ATOM 1597 C CE . LYS A 1 207 ? -31.286 -20.857 58.538 1.00 20.21 ? 207 LYS A CE 1 ATOM 1598 N NZ . LYS A 1 207 ? -30.689 -19.652 57.983 1.00 31.55 ? 207 LYS A NZ 1 ATOM 1599 N N . SER A 1 208 ? -28.618 -24.876 61.795 1.00 29.20 ? 208 SER A N 1 ATOM 1600 C CA . SER A 1 208 ? -28.354 -25.990 62.696 1.00 30.14 ? 208 SER A CA 1 ATOM 1601 C C . SER A 1 208 ? -29.536 -26.380 63.542 1.00 24.37 ? 208 SER A C 1 ATOM 1602 O O . SER A 1 208 ? -30.521 -25.664 63.631 1.00 29.12 ? 208 SER A O 1 ATOM 1603 C CB . SER A 1 208 ? -27.200 -25.654 63.619 1.00 23.77 ? 208 SER A CB 1 ATOM 1604 O OG . SER A 1 208 ? -27.537 -24.549 64.410 1.00 24.03 ? 208 SER A OG 1 ATOM 1605 N N . PHE A 1 209 ? -29.424 -27.535 64.175 1.00 28.65 ? 209 PHE A N 1 ATOM 1606 C CA . PHE A 1 209 ? -30.480 -27.994 65.045 1.00 26.50 ? 209 PHE A CA 1 ATOM 1607 C C . PHE A 1 209 ? -29.896 -28.847 66.152 1.00 32.03 ? 209 PHE A C 1 ATOM 1608 O O . PHE A 1 209 ? -28.764 -29.327 66.043 1.00 32.91 ? 209 PHE A O 1 ATOM 1609 C CB . PHE A 1 209 ? -31.547 -28.757 64.254 1.00 21.26 ? 209 PHE A CB 1 ATOM 1610 C CG . PHE A 1 209 ? -31.059 -30.034 63.635 1.00 26.36 ? 209 PHE A CG 1 ATOM 1611 C CD1 . PHE A 1 209 ? -30.553 -30.046 62.339 1.00 26.23 ? 209 PHE A CD1 1 ATOM 1612 C CD2 . PHE A 1 209 ? -31.123 -31.233 64.336 1.00 28.59 ? 209 PHE A CD2 1 ATOM 1613 C CE1 . PHE A 1 209 ? -30.108 -31.224 61.757 1.00 22.89 ? 209 PHE A CE1 1 ATOM 1614 C CE2 . PHE A 1 209 ? -30.676 -32.417 63.764 1.00 25.04 ? 209 PHE A CE2 1 ATOM 1615 C CZ . PHE A 1 209 ? -30.170 -32.410 62.469 1.00 29.05 ? 209 PHE A CZ 1 ATOM 1616 N N . ASN A 1 210 ? -30.656 -29.002 67.231 1.00 34.66 ? 210 ASN A N 1 ATOM 1617 C CA . ASN A 1 210 ? -30.344 -29.992 68.240 1.00 32.91 ? 210 ASN A CA 1 ATOM 1618 C C . ASN A 1 210 ? -31.264 -31.178 68.027 1.00 32.59 ? 210 ASN A C 1 ATOM 1619 O O . ASN A 1 210 ? -32.485 -31.011 67.917 1.00 37.94 ? 210 ASN A O 1 ATOM 1620 C CB . ASN A 1 210 ? -30.547 -29.414 69.646 1.00 37.06 ? 210 ASN A CB 1 ATOM 1621 C CG . ASN A 1 210 ? -29.804 -28.121 69.850 1.00 38.18 ? 210 ASN A CG 1 ATOM 1622 O OD1 . ASN A 1 210 ? -28.844 -27.826 69.138 1.00 43.96 ? 210 ASN A OD1 1 ATOM 1623 N ND2 . ASN A 1 210 ? -30.246 -27.331 70.817 1.00 43.32 ? 210 ASN A ND2 1 ATOM 1624 N N . ARG A 1 211 ? -30.679 -32.368 67.963 1.00 25.40 ? 211 ARG A N 1 ATOM 1625 C CA . ARG A 1 211 ? -31.461 -33.580 67.800 1.00 31.09 ? 211 ARG A CA 1 ATOM 1626 C C . ARG A 1 211 ? -32.565 -33.692 68.876 1.00 36.64 ? 211 ARG A C 1 ATOM 1627 O O . ARG A 1 211 ? -32.277 -33.858 70.063 1.00 35.77 ? 211 ARG A O 1 ATOM 1628 C CB . ARG A 1 211 ? -30.559 -34.810 67.814 1.00 22.00 ? 211 ARG A CB 1 ATOM 1629 C CG . ARG A 1 211 ? -31.342 -36.105 67.834 1.00 27.60 ? 211 ARG A CG 1 ATOM 1630 C CD . ARG A 1 211 ? -30.453 -37.327 67.935 1.00 27.66 ? 211 ARG A CD 1 ATOM 1631 N NE . ARG A 1 211 ? -29.379 -37.162 68.898 1.00 25.41 ? 211 ARG A NE 1 ATOM 1632 C CZ . ARG A 1 211 ? -29.550 -37.143 70.218 1.00 38.60 ? 211 ARG A CZ 1 ATOM 1633 N NH1 . ARG A 1 211 ? -30.767 -37.262 70.747 1.00 30.43 ? 211 ARG A NH1 1 ATOM 1634 N NH2 . ARG A 1 211 ? -28.502 -36.991 71.017 1.00 36.82 ? 211 ARG A NH2 1 ATOM 1635 N N . GLY A 1 212 ? -33.826 -33.573 68.463 1.00 35.64 ? 212 GLY A N 1 ATOM 1636 C CA . GLY A 1 212 ? -34.947 -33.637 69.392 1.00 40.75 ? 212 GLY A CA 1 ATOM 1637 C C . GLY A 1 212 ? -35.090 -32.415 70.282 1.00 33.72 ? 212 GLY A C 1 ATOM 1638 O O . GLY A 1 212 ? -35.460 -31.321 69.827 1.00 41.65 ? 212 GLY A O 1 ATOM 1639 N N . GLN B 2 1 ? -50.131 -34.835 15.613 1.00 38.26 ? 1 GLN B N 1 ATOM 1640 C CA . GLN B 2 1 ? -48.828 -34.543 16.199 1.00 30.07 ? 1 GLN B CA 1 ATOM 1641 C C . GLN B 2 1 ? -47.868 -35.726 16.021 1.00 30.53 ? 1 GLN B C 1 ATOM 1642 O O . GLN B 2 1 ? -48.202 -36.853 16.390 1.00 33.47 ? 1 GLN B O 1 ATOM 1643 C CB . GLN B 2 1 ? -48.996 -34.217 17.685 1.00 30.29 ? 1 GLN B CB 1 ATOM 1644 N N . VAL B 2 2 ? -46.693 -35.482 15.441 1.00 25.28 ? 2 VAL B N 1 ATOM 1645 C CA . VAL B 2 2 ? -45.678 -36.530 15.339 1.00 24.45 ? 2 VAL B CA 1 ATOM 1646 C C . VAL B 2 2 ? -45.011 -36.808 16.687 1.00 28.76 ? 2 VAL B C 1 ATOM 1647 O O . VAL B 2 2 ? -44.485 -35.894 17.321 1.00 30.57 ? 2 VAL B O 1 ATOM 1648 C CB . VAL B 2 2 ? -44.577 -36.167 14.330 1.00 32.18 ? 2 VAL B CB 1 ATOM 1649 C CG1 . VAL B 2 2 ? -43.369 -37.115 14.476 1.00 22.73 ? 2 VAL B CG1 1 ATOM 1650 C CG2 . VAL B 2 2 ? -45.130 -36.206 12.923 1.00 28.99 ? 2 VAL B CG2 1 ATOM 1651 N N . GLN B 2 3 ? -45.031 -38.068 17.115 1.00 23.43 ? 3 GLN B N 1 ATOM 1652 C CA . GLN B 2 3 ? -44.413 -38.480 18.374 1.00 26.57 ? 3 GLN B CA 1 ATOM 1653 C C . GLN B 2 3 ? -43.689 -39.826 18.238 1.00 27.93 ? 3 GLN B C 1 ATOM 1654 O O . GLN B 2 3 ? -44.028 -40.651 17.386 1.00 26.77 ? 3 GLN B O 1 ATOM 1655 C CB . GLN B 2 3 ? -45.468 -38.605 19.471 1.00 27.09 ? 3 GLN B CB 1 ATOM 1656 C CG . GLN B 2 3 ? -46.166 -37.309 19.821 1.00 40.14 ? 3 GLN B CG 1 ATOM 1657 C CD . GLN B 2 3 ? -47.085 -37.448 21.024 1.00 49.39 ? 3 GLN B CD 1 ATOM 1658 O OE1 . GLN B 2 3 ? -47.606 -38.529 21.300 1.00 46.37 ? 3 GLN B OE1 1 ATOM 1659 N NE2 . GLN B 2 3 ? -47.287 -36.348 21.746 1.00 59.46 ? 3 GLN B NE2 1 ATOM 1660 N N . LEU B 2 4 ? -42.684 -40.037 19.081 1.00 22.68 ? 4 LEU B N 1 ATOM 1661 C CA . LEU B 2 4 ? -42.058 -41.348 19.222 1.00 25.86 ? 4 LEU B CA 1 ATOM 1662 C C . LEU B 2 4 ? -41.927 -41.630 20.720 1.00 27.51 ? 4 LEU B C 1 ATOM 1663 O O . LEU B 2 4 ? -41.422 -40.795 21.471 1.00 25.87 ? 4 LEU B O 1 ATOM 1664 C CB . LEU B 2 4 ? -40.691 -41.419 18.517 1.00 19.60 ? 4 LEU B CB 1 ATOM 1665 C CG . LEU B 2 4 ? -40.557 -41.144 17.003 1.00 19.83 ? 4 LEU B CG 1 ATOM 1666 C CD1 . LEU B 2 4 ? -40.658 -39.663 16.667 1.00 19.85 ? 4 LEU B CD1 1 ATOM 1667 C CD2 . LEU B 2 4 ? -39.257 -41.688 16.444 1.00 16.51 ? 4 LEU B CD2 1 ATOM 1668 N N . LYS B 2 5 ? -42.420 -42.784 21.166 1.00 29.20 ? 5 LYS B N 1 ATOM 1669 C CA . LYS B 2 5 ? -42.340 -43.132 22.581 1.00 23.82 ? 5 LYS B CA 1 ATOM 1670 C C . LYS B 2 5 ? -41.602 -44.432 22.723 1.00 25.98 ? 5 LYS B C 1 ATOM 1671 O O . LYS B 2 5 ? -41.936 -45.422 22.078 1.00 22.88 ? 5 LYS B O 1 ATOM 1672 C CB . LYS B 2 5 ? -43.728 -43.217 23.210 1.00 33.62 ? 5 LYS B CB 1 ATOM 1673 C CG . LYS B 2 5 ? -44.583 -41.998 22.941 1.00 30.69 ? 5 LYS B CG 1 ATOM 1674 C CD . LYS B 2 5 ? -45.904 -42.067 23.683 1.00 59.98 ? 5 LYS B CD 1 ATOM 1675 C CE . LYS B 2 5 ? -46.821 -40.934 23.246 1.00 56.01 ? 5 LYS B CE 1 ATOM 1676 N NZ . LYS B 2 5 ? -46.056 -39.657 23.083 1.00 53.69 ? 5 LYS B NZ 1 ATOM 1677 N N . GLN B 2 6 ? -40.560 -44.412 23.543 1.00 23.72 ? 6 GLN B N 1 ATOM 1678 C CA . GLN B 2 6 ? -39.701 -45.565 23.686 1.00 19.39 ? 6 GLN B CA 1 ATOM 1679 C C . GLN B 2 6 ? -40.088 -46.311 24.952 1.00 27.36 ? 6 GLN B C 1 ATOM 1680 O O . GLN B 2 6 ? -40.658 -45.722 25.868 1.00 21.76 ? 6 GLN B O 1 ATOM 1681 C CB . GLN B 2 6 ? -38.244 -45.123 23.776 1.00 25.06 ? 6 GLN B CB 1 ATOM 1682 C CG . GLN B 2 6 ? -37.684 -44.538 22.509 1.00 20.00 ? 6 GLN B CG 1 ATOM 1683 C CD . GLN B 2 6 ? -36.309 -43.915 22.712 1.00 20.96 ? 6 GLN B CD 1 ATOM 1684 O OE1 . GLN B 2 6 ? -36.093 -42.759 22.370 1.00 19.33 ? 6 GLN B OE1 1 ATOM 1685 N NE2 . GLN B 2 6 ? -35.375 -44.686 23.251 1.00 17.37 ? 6 GLN B NE2 1 ATOM 1686 N N . SER B 2 7 ? -39.782 -47.605 25.003 1.00 18.03 ? 7 SER B N 1 ATOM 1687 C CA . SER B 2 7 ? -39.963 -48.362 26.233 1.00 19.98 ? 7 SER B CA 1 ATOM 1688 C C . SER B 2 7 ? -38.995 -47.869 27.320 1.00 30.81 ? 7 SER B C 1 ATOM 1689 O O . SER B 2 7 ? -37.935 -47.293 27.022 1.00 26.73 ? 7 SER B O 1 ATOM 1690 C CB . SER B 2 7 ? -39.792 -49.860 25.987 1.00 21.07 ? 7 SER B CB 1 ATOM 1691 O OG . SER B 2 7 ? -38.681 -50.130 25.155 1.00 28.65 ? 7 SER B OG 1 ATOM 1692 N N . GLY B 2 8 ? -39.368 -48.100 28.577 1.00 29.22 ? 8 GLY B N 1 ATOM 1693 C CA . GLY B 2 8 ? -38.637 -47.580 29.724 1.00 19.32 ? 8 GLY B CA 1 ATOM 1694 C C . GLY B 2 8 ? -37.213 -48.059 29.977 1.00 20.35 ? 8 GLY B C 1 ATOM 1695 O O . GLY B 2 8 ? -36.756 -49.074 29.451 1.00 21.71 ? 8 GLY B O 1 ATOM 1696 N N . PRO B 2 9 ? -36.509 -47.336 30.847 1.00 21.23 ? 9 PRO B N 1 ATOM 1697 C CA . PRO B 2 9 ? -35.081 -47.540 31.076 1.00 21.90 ? 9 PRO B CA 1 ATOM 1698 C C . PRO B 2 9 ? -34.851 -48.763 31.942 1.00 32.27 ? 9 PRO B C 1 ATOM 1699 O O . PRO B 2 9 ? -35.781 -49.248 32.606 1.00 31.86 ? 9 PRO B O 1 ATOM 1700 C CB . PRO B 2 9 ? -34.688 -46.283 31.842 1.00 24.54 ? 9 PRO B CB 1 ATOM 1701 C CG . PRO B 2 9 ? -35.939 -45.943 32.640 1.00 20.98 ? 9 PRO B CG 1 ATOM 1702 C CD . PRO B 2 9 ? -37.110 -46.429 31.844 1.00 24.76 ? 9 PRO B CD 1 ATOM 1703 N N . GLY B 2 10 ? -33.624 -49.263 31.941 1.00 28.12 ? 10 GLY B N 1 ATOM 1704 C CA . GLY B 2 10 ? -33.329 -50.411 32.763 1.00 27.08 ? 10 GLY B CA 1 ATOM 1705 C C . GLY B 2 10 ? -31.946 -50.994 32.619 1.00 29.04 ? 10 GLY B C 1 ATOM 1706 O O . GLY B 2 10 ? -31.097 -50.522 31.850 1.00 28.16 ? 10 GLY B O 1 ATOM 1707 N N . LEU B 2 11 ? -31.757 -52.069 33.367 1.00 25.93 ? 11 LEU B N 1 ATOM 1708 C CA . LEU B 2 11 ? -30.485 -52.715 33.522 1.00 25.97 ? 11 LEU B CA 1 ATOM 1709 C C . LEU B 2 11 ? -30.323 -53.809 32.465 1.00 29.55 ? 11 LEU B C 1 ATOM 1710 O O . LEU B 2 11 ? -31.280 -54.475 32.095 1.00 30.99 ? 11 LEU B O 1 ATOM 1711 C CB . LEU B 2 11 ? -30.436 -53.313 34.923 1.00 19.37 ? 11 LEU B CB 1 ATOM 1712 C CG . LEU B 2 11 ? -29.082 -53.600 35.544 1.00 33.13 ? 11 LEU B CG 1 ATOM 1713 C CD1 . LEU B 2 11 ? -28.192 -52.402 35.362 1.00 31.90 ? 11 LEU B CD1 1 ATOM 1714 C CD2 . LEU B 2 11 ? -29.264 -53.921 37.022 1.00 28.05 ? 11 LEU B CD2 1 ATOM 1715 N N . VAL B 2 12 ? -29.103 -53.973 31.972 1.00 28.88 ? 12 VAL B N 1 ATOM 1716 C CA . VAL B 2 12 ? -28.748 -55.106 31.136 1.00 25.54 ? 12 VAL B CA 1 ATOM 1717 C C . VAL B 2 12 ? -27.459 -55.695 31.698 1.00 31.35 ? 12 VAL B C 1 ATOM 1718 O O . VAL B 2 12 ? -26.471 -54.975 31.865 1.00 27.56 ? 12 VAL B O 1 ATOM 1719 C CB . VAL B 2 12 ? -28.521 -54.682 29.664 1.00 29.93 ? 12 VAL B CB 1 ATOM 1720 C CG1 . VAL B 2 12 ? -27.922 -55.823 28.849 1.00 31.89 ? 12 VAL B CG1 1 ATOM 1721 C CG2 . VAL B 2 12 ? -29.815 -54.209 29.038 1.00 23.92 ? 12 VAL B CG2 1 ATOM 1722 N N . GLN B 2 13 ? -27.470 -56.993 32.002 1.00 34.18 ? 13 GLN B N 1 ATOM 1723 C CA . GLN B 2 13 ? -26.269 -57.664 32.500 1.00 35.72 ? 13 GLN B CA 1 ATOM 1724 C C . GLN B 2 13 ? -25.191 -57.656 31.416 1.00 37.26 ? 13 GLN B C 1 ATOM 1725 O O . GLN B 2 13 ? -25.497 -57.613 30.227 1.00 33.52 ? 13 GLN B O 1 ATOM 1726 C CB . GLN B 2 13 ? -26.569 -59.105 32.950 1.00 33.72 ? 13 GLN B CB 1 ATOM 1727 C CG . GLN B 2 13 ? -27.615 -59.254 34.065 1.00 36.39 ? 13 GLN B CG 1 ATOM 1728 C CD . GLN B 2 13 ? -27.277 -58.464 35.342 1.00 47.85 ? 13 GLN B CD 1 ATOM 1729 O OE1 . GLN B 2 13 ? -28.126 -57.749 35.896 1.00 37.98 ? 13 GLN B OE1 1 ATOM 1730 N NE2 . GLN B 2 13 ? -26.042 -58.601 35.814 1.00 42.99 ? 13 GLN B NE2 1 ATOM 1731 N N . PRO B 2 14 ? -23.919 -57.658 31.825 1.00 36.15 ? 14 PRO B N 1 ATOM 1732 C CA . PRO B 2 14 ? -22.827 -57.795 30.860 1.00 28.59 ? 14 PRO B CA 1 ATOM 1733 C C . PRO B 2 14 ? -23.015 -59.018 29.974 1.00 35.69 ? 14 PRO B C 1 ATOM 1734 O O . PRO B 2 14 ? -23.528 -60.040 30.437 1.00 39.33 ? 14 PRO B O 1 ATOM 1735 C CB . PRO B 2 14 ? -21.607 -57.951 31.755 1.00 32.17 ? 14 PRO B CB 1 ATOM 1736 C CG . PRO B 2 14 ? -21.953 -57.130 32.948 1.00 36.22 ? 14 PRO B CG 1 ATOM 1737 C CD . PRO B 2 14 ? -23.426 -57.333 33.171 1.00 28.10 ? 14 PRO B CD 1 ATOM 1738 N N . SER B 2 15 ? -22.633 -58.874 28.705 1.00 41.96 ? 15 SER B N 1 ATOM 1739 C CA . SER B 2 15 ? -22.776 -59.904 27.668 1.00 39.01 ? 15 SER B CA 1 ATOM 1740 C C . SER B 2 15 ? -24.219 -60.256 27.296 1.00 37.26 ? 15 SER B C 1 ATOM 1741 O O . SER B 2 15 ? -24.454 -61.255 26.624 1.00 45.11 ? 15 SER B O 1 ATOM 1742 C CB . SER B 2 15 ? -21.995 -61.172 28.022 1.00 39.67 ? 15 SER B CB 1 ATOM 1743 O OG . SER B 2 15 ? -22.785 -62.040 28.811 1.00 54.37 ? 15 SER B OG 1 ATOM 1744 N N . GLN B 2 16 ? -25.176 -59.433 27.713 1.00 41.35 ? 16 GLN B N 1 ATOM 1745 C CA . GLN B 2 16 ? -26.589 -59.662 27.392 1.00 34.13 ? 16 GLN B CA 1 ATOM 1746 C C . GLN B 2 16 ? -27.113 -58.715 26.318 1.00 33.74 ? 16 GLN B C 1 ATOM 1747 O O . GLN B 2 16 ? -26.405 -57.813 25.870 1.00 44.04 ? 16 GLN B O 1 ATOM 1748 C CB . GLN B 2 16 ? -27.445 -59.510 28.640 1.00 43.29 ? 16 GLN B CB 1 ATOM 1749 C CG . GLN B 2 16 ? -27.146 -60.535 29.702 1.00 46.27 ? 16 GLN B CG 1 ATOM 1750 C CD . GLN B 2 16 ? -27.912 -61.815 29.477 1.00 57.85 ? 16 GLN B CD 1 ATOM 1751 O OE1 . GLN B 2 16 ? -27.633 -62.566 28.540 1.00 57.53 ? 16 GLN B OE1 1 ATOM 1752 N NE2 . GLN B 2 16 ? -28.897 -62.072 30.335 1.00 61.76 ? 16 GLN B NE2 1 ATOM 1753 N N . SER B 2 17 ? -28.366 -58.911 25.916 1.00 33.62 ? 17 SER B N 1 ATOM 1754 C CA . SER B 2 17 ? -28.938 -58.150 24.808 1.00 35.93 ? 17 SER B CA 1 ATOM 1755 C C . SER B 2 17 ? -29.884 -57.028 25.226 1.00 36.54 ? 17 SER B C 1 ATOM 1756 O O . SER B 2 17 ? -30.604 -57.134 26.214 1.00 34.76 ? 17 SER B O 1 ATOM 1757 C CB . SER B 2 17 ? -29.641 -59.078 23.820 1.00 34.09 ? 17 SER B CB 1 ATOM 1758 O OG . SER B 2 17 ? -30.588 -59.887 24.487 1.00 48.97 ? 17 SER B OG 1 ATOM 1759 N N . LEU B 2 18 ? -29.874 -55.955 24.442 1.00 36.26 ? 18 LEU B N 1 ATOM 1760 C CA . LEU B 2 18 ? -30.726 -54.810 24.680 1.00 23.38 ? 18 LEU B CA 1 ATOM 1761 C C . LEU B 2 18 ? -31.941 -54.889 23.759 1.00 25.98 ? 18 LEU B C 1 ATOM 1762 O O . LEU B 2 18 ? -31.796 -55.151 22.579 1.00 29.24 ? 18 LEU B O 1 ATOM 1763 C CB . LEU B 2 18 ? -29.933 -53.524 24.432 1.00 23.04 ? 18 LEU B CB 1 ATOM 1764 C CG . LEU B 2 18 ? -30.689 -52.203 24.591 1.00 26.92 ? 18 LEU B CG 1 ATOM 1765 C CD1 . LEU B 2 18 ? -31.422 -52.169 25.922 1.00 18.86 ? 18 LEU B CD1 1 ATOM 1766 C CD2 . LEU B 2 18 ? -29.743 -51.026 24.480 1.00 19.10 ? 18 LEU B CD2 1 ATOM 1767 N N . SER B 2 19 ? -33.138 -54.692 24.303 1.00 21.31 ? 19 SER B N 1 ATOM 1768 C CA . SER B 2 19 ? -34.332 -54.606 23.480 1.00 22.51 ? 19 SER B CA 1 ATOM 1769 C C . SER B 2 19 ? -35.087 -53.330 23.826 1.00 27.07 ? 19 SER B C 1 ATOM 1770 O O . SER B 2 19 ? -35.469 -53.122 24.980 1.00 23.49 ? 19 SER B O 1 ATOM 1771 C CB . SER B 2 19 ? -35.236 -55.822 23.677 1.00 27.94 ? 19 SER B CB 1 ATOM 1772 O OG . SER B 2 19 ? -34.670 -56.987 23.103 1.00 32.95 ? 19 SER B OG 1 ATOM 1773 N N . ILE B 2 20 ? -35.281 -52.471 22.828 1.00 21.78 ? 20 ILE B N 1 ATOM 1774 C CA . ILE B 2 20 ? -36.062 -51.256 22.996 1.00 19.45 ? 20 ILE B CA 1 ATOM 1775 C C . ILE B 2 20 ? -37.123 -51.154 21.922 1.00 24.64 ? 20 ILE B C 1 ATOM 1776 O O . ILE B 2 20 ? -36.864 -51.430 20.746 1.00 28.66 ? 20 ILE B O 1 ATOM 1777 C CB . ILE B 2 20 ? -35.176 -50.013 22.936 1.00 24.99 ? 20 ILE B CB 1 ATOM 1778 C CG1 . ILE B 2 20 ? -34.038 -50.121 23.960 1.00 23.94 ? 20 ILE B CG1 1 ATOM 1779 C CG2 . ILE B 2 20 ? -36.005 -48.749 23.151 1.00 17.25 ? 20 ILE B CG2 1 ATOM 1780 C CD1 . ILE B 2 20 ? -33.024 -49.006 23.822 1.00 22.68 ? 20 ILE B CD1 1 ATOM 1781 N N . THR B 2 21 ? -38.329 -50.775 22.325 1.00 26.53 ? 21 THR B N 1 ATOM 1782 C CA . THR B 2 21 ? -39.423 -50.601 21.373 1.00 21.09 ? 21 THR B CA 1 ATOM 1783 C C . THR B 2 21 ? -39.717 -49.123 21.210 1.00 25.13 ? 21 THR B C 1 ATOM 1784 O O . THR B 2 21 ? -39.816 -48.392 22.202 1.00 24.38 ? 21 THR B O 1 ATOM 1785 C CB . THR B 2 21 ? -40.705 -51.335 21.816 1.00 24.15 ? 21 THR B CB 1 ATOM 1786 O OG1 . THR B 2 21 ? -40.535 -52.740 21.614 1.00 23.52 ? 21 THR B OG1 1 ATOM 1787 C CG2 . THR B 2 21 ? -41.932 -50.854 21.020 1.00 27.36 ? 21 THR B CG2 1 ATOM 1788 N N . CYS B 2 22 ? -39.836 -48.691 19.956 1.00 18.78 ? 22 CYS B N 1 ATOM 1789 C CA . CYS B 2 22 ? -40.220 -47.324 19.622 1.00 21.30 ? 22 CYS B CA 1 ATOM 1790 C C . CYS B 2 22 ? -41.620 -47.383 19.033 1.00 26.56 ? 22 CYS B C 1 ATOM 1791 O O . CYS B 2 22 ? -41.858 -48.066 18.030 1.00 23.34 ? 22 CYS B O 1 ATOM 1792 C CB . CYS B 2 22 ? -39.243 -46.732 18.589 1.00 26.57 ? 22 CYS B CB 1 ATOM 1793 S SG . CYS B 2 22 ? -39.442 -44.958 18.216 1.00 28.69 ? 22 CYS B SG 1 ATOM 1794 N N . THR B 2 23 ? -42.555 -46.690 19.670 1.00 26.86 ? 23 THR B N 1 ATOM 1795 C CA . THR B 2 23 ? -43.917 -46.629 19.153 1.00 25.99 ? 23 THR B CA 1 ATOM 1796 C C . THR B 2 23 ? -44.185 -45.235 18.621 1.00 25.67 ? 23 THR B C 1 ATOM 1797 O O . THR B 2 23 ? -44.161 -44.258 19.371 1.00 31.41 ? 23 THR B O 1 ATOM 1798 C CB . THR B 2 23 ? -44.973 -46.981 20.209 1.00 25.96 ? 23 THR B CB 1 ATOM 1799 O OG1 . THR B 2 23 ? -44.754 -48.316 20.694 1.00 27.83 ? 23 THR B OG1 1 ATOM 1800 C CG2 . THR B 2 23 ? -46.370 -46.888 19.595 1.00 21.96 ? 23 THR B CG2 1 ATOM 1801 N N . VAL B 2 24 ? -44.429 -45.145 17.321 1.00 21.94 ? 24 VAL B N 1 ATOM 1802 C CA . VAL B 2 24 ? -44.582 -43.858 16.681 1.00 24.86 ? 24 VAL B CA 1 ATOM 1803 C C . VAL B 2 24 ? -46.045 -43.577 16.416 1.00 26.05 ? 24 VAL B C 1 ATOM 1804 O O . VAL B 2 24 ? -46.849 -44.501 16.276 1.00 25.53 ? 24 VAL B O 1 ATOM 1805 C CB . VAL B 2 24 ? -43.815 -43.802 15.342 1.00 30.56 ? 24 VAL B CB 1 ATOM 1806 C CG1 . VAL B 2 24 ? -42.388 -44.316 15.522 1.00 22.58 ? 24 VAL B CG1 1 ATOM 1807 C CG2 . VAL B 2 24 ? -44.557 -44.586 14.246 1.00 21.14 ? 24 VAL B CG2 1 ATOM 1808 N N . SER B 2 25 ? -46.384 -42.292 16.359 1.00 22.26 ? 25 SER B N 1 ATOM 1809 C CA . SER B 2 25 ? -47.726 -41.862 15.998 1.00 18.44 ? 25 SER B CA 1 ATOM 1810 C C . SER B 2 25 ? -47.635 -40.478 15.358 1.00 25.35 ? 25 SER B C 1 ATOM 1811 O O . SER B 2 25 ? -46.658 -39.757 15.569 1.00 32.08 ? 25 SER B O 1 ATOM 1812 C CB . SER B 2 25 ? -48.638 -41.840 17.218 1.00 15.26 ? 25 SER B CB 1 ATOM 1813 O OG . SER B 2 25 ? -48.192 -40.881 18.156 1.00 30.88 ? 25 SER B OG 1 ATOM 1814 N N . GLY B 2 26 ? -48.641 -40.118 14.567 1.00 23.25 ? 26 GLY B N 1 ATOM 1815 C CA . GLY B 2 26 ? -48.610 -38.885 13.800 1.00 26.45 ? 26 GLY B CA 1 ATOM 1816 C C . GLY B 2 26 ? -48.030 -39.090 12.406 1.00 28.12 ? 26 GLY B C 1 ATOM 1817 O O . GLY B 2 26 ? -47.932 -38.151 11.616 1.00 25.87 ? 26 GLY B O 1 ATOM 1818 N N . PHE B 2 27 ? -47.622 -40.321 12.113 1.00 18.92 ? 27 PHE B N 1 ATOM 1819 C CA . PHE B 2 27 ? -47.132 -40.678 10.784 1.00 22.89 ? 27 PHE B CA 1 ATOM 1820 C C . PHE B 2 27 ? -47.091 -42.196 10.624 1.00 21.63 ? 27 PHE B C 1 ATOM 1821 O O . PHE B 2 27 ? -47.347 -42.941 11.563 1.00 26.23 ? 27 PHE B O 1 ATOM 1822 C CB . PHE B 2 27 ? -45.757 -40.044 10.485 1.00 20.77 ? 27 PHE B CB 1 ATOM 1823 C CG . PHE B 2 27 ? -44.631 -40.575 11.335 1.00 27.15 ? 27 PHE B CG 1 ATOM 1824 C CD1 . PHE B 2 27 ? -44.422 -40.083 12.628 1.00 28.80 ? 27 PHE B CD1 1 ATOM 1825 C CD2 . PHE B 2 27 ? -43.779 -41.566 10.846 1.00 24.18 ? 27 PHE B CD2 1 ATOM 1826 C CE1 . PHE B 2 27 ? -43.386 -40.566 13.417 1.00 23.52 ? 27 PHE B CE1 1 ATOM 1827 C CE2 . PHE B 2 27 ? -42.740 -42.058 11.622 1.00 24.13 ? 27 PHE B CE2 1 ATOM 1828 C CZ . PHE B 2 27 ? -42.537 -41.557 12.914 1.00 23.01 ? 27 PHE B CZ 1 ATOM 1829 N N . SER B 2 28 ? -46.758 -42.652 9.431 1.00 28.52 ? 28 SER B N 1 ATOM 1830 C CA . SER B 2 28 ? -46.796 -44.071 9.128 1.00 28.62 ? 28 SER B CA 1 ATOM 1831 C C . SER B 2 28 ? -45.390 -44.579 8.814 1.00 29.05 ? 28 SER B C 1 ATOM 1832 O O . SER B 2 28 ? -44.625 -43.932 8.091 1.00 27.58 ? 28 SER B O 1 ATOM 1833 C CB . SER B 2 28 ? -47.753 -44.336 7.960 1.00 17.60 ? 28 SER B CB 1 ATOM 1834 O OG . SER B 2 28 ? -47.578 -45.644 7.452 1.00 25.65 ? 28 SER B OG 1 ATOM 1835 N N . LEU B 2 29 ? -45.056 -45.740 9.360 1.00 23.62 ? 29 LEU B N 1 ATOM 1836 C CA . LEU B 2 29 ? -43.740 -46.328 9.150 1.00 27.64 ? 29 LEU B CA 1 ATOM 1837 C C . LEU B 2 29 ? -43.565 -46.761 7.708 1.00 28.26 ? 29 LEU B C 1 ATOM 1838 O O . LEU B 2 29 ? -42.455 -47.073 7.282 1.00 29.55 ? 29 LEU B O 1 ATOM 1839 C CB . LEU B 2 29 ? -43.518 -47.516 10.092 1.00 21.54 ? 29 LEU B CB 1 ATOM 1840 C CG . LEU B 2 29 ? -43.434 -47.143 11.579 1.00 28.42 ? 29 LEU B CG 1 ATOM 1841 C CD1 . LEU B 2 29 ? -43.407 -48.377 12.470 1.00 30.78 ? 29 LEU B CD1 1 ATOM 1842 C CD2 . LEU B 2 29 ? -42.227 -46.278 11.849 1.00 17.71 ? 29 LEU B CD2 1 ATOM 1843 N N . THR B 2 30 ? -44.661 -46.786 6.957 1.00 27.38 ? 30 THR B N 1 ATOM 1844 C CA . THR B 2 30 ? -44.590 -47.116 5.538 1.00 33.02 ? 30 THR B CA 1 ATOM 1845 C C . THR B 2 30 ? -44.071 -45.934 4.727 1.00 26.83 ? 30 THR B C 1 ATOM 1846 O O . THR B 2 30 ? -43.557 -46.128 3.633 1.00 26.57 ? 30 THR B O 1 ATOM 1847 C CB . THR B 2 30 ? -45.944 -47.558 4.980 1.00 32.92 ? 30 THR B CB 1 ATOM 1848 O OG1 . THR B 2 30 ? -46.874 -46.469 5.078 1.00 35.96 ? 30 THR B OG1 1 ATOM 1849 C CG2 . THR B 2 30 ? -46.461 -48.764 5.758 1.00 31.79 ? 30 THR B CG2 1 ATOM 1850 N N . ASN B 2 31 ? -44.185 -44.725 5.285 1.00 26.91 ? 31 ASN B N 1 ATOM 1851 C CA . ASN B 2 31 ? -43.687 -43.503 4.636 1.00 34.20 ? 31 ASN B CA 1 ATOM 1852 C C . ASN B 2 31 ? -42.399 -42.934 5.219 1.00 28.05 ? 31 ASN B C 1 ATOM 1853 O O . ASN B 2 31 ? -41.805 -42.035 4.634 1.00 30.29 ? 31 ASN B O 1 ATOM 1854 C CB . ASN B 2 31 ? -44.736 -42.392 4.669 1.00 29.79 ? 31 ASN B CB 1 ATOM 1855 C CG . ASN B 2 31 ? -46.030 -42.803 4.026 1.00 33.68 ? 31 ASN B CG 1 ATOM 1856 O OD1 . ASN B 2 31 ? -46.033 -43.476 2.994 1.00 42.46 ? 31 ASN B OD1 1 ATOM 1857 N ND2 . ASN B 2 31 ? -47.142 -42.415 4.635 1.00 27.04 ? 31 ASN B ND2 1 ATOM 1858 N N . TYR B 2 32 ? -41.975 -43.413 6.382 1.00 25.90 ? 32 TYR B N 1 ATOM 1859 C CA . TYR B 2 32 ? -40.757 -42.869 6.978 1.00 22.60 ? 32 TYR B CA 1 ATOM 1860 C C . TYR B 2 32 ? -39.810 -43.911 7.527 1.00 27.32 ? 32 TYR B C 1 ATOM 1861 O O . TYR B 2 32 ? -40.228 -44.971 8.002 1.00 29.93 ? 32 TYR B O 1 ATOM 1862 C CB . TYR B 2 32 ? -41.080 -41.856 8.073 1.00 22.05 ? 32 TYR B CB 1 ATOM 1863 C CG . TYR B 2 32 ? -41.672 -40.582 7.557 1.00 26.05 ? 32 TYR B CG 1 ATOM 1864 C CD1 . TYR B 2 32 ? -40.860 -39.505 7.231 1.00 24.41 ? 32 TYR B CD1 1 ATOM 1865 C CD2 . TYR B 2 32 ? -43.047 -40.454 7.387 1.00 29.37 ? 32 TYR B CD2 1 ATOM 1866 C CE1 . TYR B 2 32 ? -41.403 -38.324 6.750 1.00 31.33 ? 32 TYR B CE1 1 ATOM 1867 C CE2 . TYR B 2 32 ? -43.601 -39.279 6.911 1.00 28.72 ? 32 TYR B CE2 1 ATOM 1868 C CZ . TYR B 2 32 ? -42.775 -38.219 6.591 1.00 32.95 ? 32 TYR B CZ 1 ATOM 1869 O OH . TYR B 2 32 ? -43.317 -37.052 6.107 1.00 42.89 ? 32 TYR B OH 1 ATOM 1870 N N . GLY B 2 33 ? -38.522 -43.589 7.461 1.00 35.60 ? 33 GLY B N 1 ATOM 1871 C CA . GLY B 2 33 ? -37.501 -44.379 8.119 1.00 28.73 ? 33 GLY B CA 1 ATOM 1872 C C . GLY B 2 33 ? -37.391 -43.964 9.572 1.00 25.50 ? 33 GLY B C 1 ATOM 1873 O O . GLY B 2 33 ? -37.674 -42.814 9.931 1.00 19.53 ? 33 GLY B O 1 ATOM 1874 N N . VAL B 2 34 ? -36.987 -44.906 10.415 1.00 22.97 ? 34 VAL B N 1 ATOM 1875 C CA . VAL B 2 34 ? -36.781 -44.614 11.831 1.00 25.07 ? 34 VAL B CA 1 ATOM 1876 C C . VAL B 2 34 ? -35.337 -44.912 12.203 1.00 23.73 ? 34 VAL B C 1 ATOM 1877 O O . VAL B 2 34 ? -34.833 -46.015 11.943 1.00 22.61 ? 34 VAL B O 1 ATOM 1878 C CB . VAL B 2 34 ? -37.784 -45.373 12.722 1.00 23.31 ? 34 VAL B CB 1 ATOM 1879 C CG1 . VAL B 2 34 ? -37.347 -45.333 14.179 1.00 20.49 ? 34 VAL B CG1 1 ATOM 1880 C CG2 . VAL B 2 34 ? -39.168 -44.778 12.556 1.00 15.37 ? 34 VAL B CG2 1 ATOM 1881 N N . HIS B 2 35 ? -34.666 -43.908 12.770 1.00 18.83 ? 35 HIS B N 1 ATOM 1882 C CA . HIS B 2 35 ? -33.237 -44.010 13.060 1.00 23.32 ? 35 HIS B CA 1 ATOM 1883 C C . HIS B 2 35 ? -32.988 -44.279 14.533 1.00 24.87 ? 35 HIS B C 1 ATOM 1884 O O . HIS B 2 35 ? -33.817 -43.943 15.381 1.00 22.32 ? 35 HIS B O 1 ATOM 1885 C CB . HIS B 2 35 ? -32.508 -42.713 12.695 1.00 23.65 ? 35 HIS B CB 1 ATOM 1886 C CG . HIS B 2 35 ? -32.532 -42.379 11.239 1.00 22.97 ? 35 HIS B CG 1 ATOM 1887 N ND1 . HIS B 2 35 ? -31.449 -42.591 10.413 1.00 16.00 ? 35 HIS B ND1 1 ATOM 1888 C CD2 . HIS B 2 35 ? -33.495 -41.816 10.465 1.00 18.41 ? 35 HIS B CD2 1 ATOM 1889 C CE1 . HIS B 2 35 ? -31.750 -42.189 9.188 1.00 26.66 ? 35 HIS B CE1 1 ATOM 1890 N NE2 . HIS B 2 35 ? -32.984 -41.711 9.196 1.00 22.31 ? 35 HIS B NE2 1 ATOM 1891 N N . TRP B 2 36 ? -31.826 -44.853 14.833 1.00 24.30 ? 36 TRP B N 1 ATOM 1892 C CA . TRP B 2 36 ? -31.399 -45.043 16.214 1.00 15.86 ? 36 TRP B CA 1 ATOM 1893 C C . TRP B 2 36 ? -30.048 -44.370 16.454 1.00 22.06 ? 36 TRP B C 1 ATOM 1894 O O . TRP B 2 36 ? -29.083 -44.558 15.695 1.00 22.90 ? 36 TRP B O 1 ATOM 1895 C CB . TRP B 2 36 ? -31.341 -46.528 16.558 1.00 19.25 ? 36 TRP B CB 1 ATOM 1896 C CG . TRP B 2 36 ? -32.691 -47.132 16.541 1.00 24.01 ? 36 TRP B CG 1 ATOM 1897 C CD1 . TRP B 2 36 ? -33.368 -47.596 15.452 1.00 23.50 ? 36 TRP B CD1 1 ATOM 1898 C CD2 . TRP B 2 36 ? -33.568 -47.304 17.661 1.00 24.37 ? 36 TRP B CD2 1 ATOM 1899 N NE1 . TRP B 2 36 ? -34.605 -48.061 15.825 1.00 27.52 ? 36 TRP B NE1 1 ATOM 1900 C CE2 . TRP B 2 36 ? -34.750 -47.892 17.178 1.00 26.99 ? 36 TRP B CE2 1 ATOM 1901 C CE3 . TRP B 2 36 ? -33.463 -47.029 19.019 1.00 20.46 ? 36 TRP B CE3 1 ATOM 1902 C CZ2 . TRP B 2 36 ? -35.817 -48.206 18.011 1.00 26.46 ? 36 TRP B CZ2 1 ATOM 1903 C CZ3 . TRP B 2 36 ? -34.521 -47.335 19.841 1.00 24.96 ? 36 TRP B CZ3 1 ATOM 1904 C CH2 . TRP B 2 36 ? -35.681 -47.922 19.339 1.00 25.36 ? 36 TRP B CH2 1 ATOM 1905 N N . VAL B 2 37 ? -30.008 -43.565 17.509 1.00 20.98 ? 37 VAL B N 1 ATOM 1906 C CA . VAL B 2 37 ? -28.835 -42.804 17.910 1.00 19.76 ? 37 VAL B CA 1 ATOM 1907 C C . VAL B 2 37 ? -28.699 -43.022 19.400 1.00 21.58 ? 37 VAL B C 1 ATOM 1908 O O . VAL B 2 37 ? -29.702 -43.053 20.113 1.00 25.83 ? 37 VAL B O 1 ATOM 1909 C CB . VAL B 2 37 ? -29.056 -41.275 17.682 1.00 20.10 ? 37 VAL B CB 1 ATOM 1910 C CG1 . VAL B 2 37 ? -27.858 -40.459 18.177 1.00 18.23 ? 37 VAL B CG1 1 ATOM 1911 C CG2 . VAL B 2 37 ? -29.368 -40.972 16.229 1.00 14.10 ? 37 VAL B CG2 1 ATOM 1912 N N . ARG B 2 38 ? -27.478 -43.173 19.888 1.00 15.33 ? 38 ARG B N 1 ATOM 1913 C CA . ARG B 2 38 ? -27.286 -43.244 21.323 1.00 16.95 ? 38 ARG B CA 1 ATOM 1914 C C . ARG B 2 38 ? -26.378 -42.128 21.804 1.00 23.61 ? 38 ARG B C 1 ATOM 1915 O O . ARG B 2 38 ? -25.715 -41.456 21.007 1.00 20.55 ? 38 ARG B O 1 ATOM 1916 C CB . ARG B 2 38 ? -26.736 -44.606 21.751 1.00 19.98 ? 38 ARG B CB 1 ATOM 1917 C CG . ARG B 2 38 ? -25.280 -44.836 21.368 1.00 20.55 ? 38 ARG B CG 1 ATOM 1918 C CD . ARG B 2 38 ? -24.792 -46.120 21.959 1.00 19.05 ? 38 ARG B CD 1 ATOM 1919 N NE . ARG B 2 38 ? -23.423 -46.413 21.562 1.00 29.12 ? 38 ARG B NE 1 ATOM 1920 C CZ . ARG B 2 38 ? -22.768 -47.503 21.944 1.00 29.56 ? 38 ARG B CZ 1 ATOM 1921 N NH1 . ARG B 2 38 ? -23.374 -48.378 22.732 1.00 28.84 ? 38 ARG B NH1 1 ATOM 1922 N NH2 . ARG B 2 38 ? -21.522 -47.716 21.544 1.00 25.66 ? 38 ARG B NH2 1 ATOM 1923 N N . GLN B 2 39 ? -26.346 -41.947 23.117 1.00 22.43 ? 39 GLN B N 1 ATOM 1924 C CA . GLN B 2 39 ? -25.521 -40.913 23.717 1.00 22.86 ? 39 GLN B CA 1 ATOM 1925 C C . GLN B 2 39 ? -24.776 -41.513 24.893 1.00 23.19 ? 39 GLN B C 1 ATOM 1926 O O . GLN B 2 39 ? -25.382 -41.815 25.919 1.00 23.81 ? 39 GLN B O 1 ATOM 1927 C CB . GLN B 2 39 ? -26.401 -39.754 24.177 1.00 19.56 ? 39 GLN B CB 1 ATOM 1928 C CG . GLN B 2 39 ? -25.642 -38.486 24.492 1.00 23.53 ? 39 GLN B CG 1 ATOM 1929 C CD . GLN B 2 39 ? -26.560 -37.294 24.737 1.00 30.34 ? 39 GLN B CD 1 ATOM 1930 O OE1 . GLN B 2 39 ? -27.684 -37.443 25.237 1.00 27.98 ? 39 GLN B OE1 1 ATOM 1931 N NE2 . GLN B 2 39 ? -26.081 -36.097 24.383 1.00 23.98 ? 39 GLN B NE2 1 ATOM 1932 N N . SER B 2 40 ? -23.467 -41.699 24.742 1.00 23.08 ? 40 SER B N 1 ATOM 1933 C CA . SER B 2 40 ? -22.666 -42.362 25.772 1.00 19.08 ? 40 SER B CA 1 ATOM 1934 C C . SER B 2 40 ? -21.728 -41.370 26.428 1.00 29.23 ? 40 SER B C 1 ATOM 1935 O O . SER B 2 40 ? -21.411 -40.336 25.836 1.00 36.24 ? 40 SER B O 1 ATOM 1936 C CB . SER B 2 40 ? -21.862 -43.522 25.181 1.00 19.27 ? 40 SER B CB 1 ATOM 1937 O OG . SER B 2 40 ? -20.775 -43.046 24.415 1.00 29.63 ? 40 SER B OG 1 ATOM 1938 N N . PRO B 2 41 ? -21.293 -41.669 27.664 1.00 26.60 ? 41 PRO B N 1 ATOM 1939 C CA . PRO B 2 41 ? -20.363 -40.795 28.380 1.00 34.06 ? 41 PRO B CA 1 ATOM 1940 C C . PRO B 2 41 ? -19.072 -40.517 27.605 1.00 35.97 ? 41 PRO B C 1 ATOM 1941 O O . PRO B 2 41 ? -18.607 -39.375 27.592 1.00 39.43 ? 41 PRO B O 1 ATOM 1942 C CB . PRO B 2 41 ? -20.075 -41.591 29.656 1.00 22.97 ? 41 PRO B CB 1 ATOM 1943 C CG . PRO B 2 41 ? -21.323 -42.313 29.899 1.00 20.67 ? 41 PRO B CG 1 ATOM 1944 C CD . PRO B 2 41 ? -21.848 -42.703 28.557 1.00 25.48 ? 41 PRO B CD 1 ATOM 1945 N N . GLY B 2 42 ? -18.513 -41.545 26.974 1.00 26.46 ? 42 GLY B N 1 ATOM 1946 C CA . GLY B 2 42 ? -17.253 -41.411 26.275 1.00 36.12 ? 42 GLY B CA 1 ATOM 1947 C C . GLY B 2 42 ? -17.407 -40.897 24.857 1.00 43.57 ? 42 GLY B C 1 ATOM 1948 O O . GLY B 2 42 ? -16.939 -39.804 24.543 1.00 51.33 ? 42 GLY B O 1 ATOM 1949 N N . LYS B 2 43 ? -18.075 -41.674 24.008 1.00 46.25 ? 43 LYS B N 1 ATOM 1950 C CA . LYS B 2 43 ? -18.227 -41.323 22.595 1.00 43.30 ? 43 LYS B CA 1 ATOM 1951 C C . LYS B 2 43 ? -19.211 -40.190 22.269 1.00 36.52 ? 43 LYS B C 1 ATOM 1952 O O . LYS B 2 43 ? -19.136 -39.609 21.188 1.00 47.38 ? 43 LYS B O 1 ATOM 1953 C CB . LYS B 2 43 ? -18.556 -42.570 21.767 1.00 42.75 ? 43 LYS B CB 1 ATOM 1954 C CG . LYS B 2 43 ? -17.393 -43.531 21.616 1.00 47.43 ? 43 LYS B CG 1 ATOM 1955 C CD . LYS B 2 43 ? -17.344 -44.116 20.206 1.00 56.84 ? 43 LYS B CD 1 ATOM 1956 C CE . LYS B 2 43 ? -16.142 -45.028 20.024 1.00 54.93 ? 43 LYS B CE 1 ATOM 1957 N NZ . LYS B 2 43 ? -16.220 -45.831 18.770 1.00 56.79 ? 43 LYS B NZ 1 ATOM 1958 N N . GLY B 2 44 ? -20.124 -39.876 23.183 1.00 31.87 ? 44 GLY B N 1 ATOM 1959 C CA . GLY B 2 44 ? -21.122 -38.856 22.910 1.00 25.52 ? 44 GLY B CA 1 ATOM 1960 C C . GLY B 2 44 ? -22.190 -39.381 21.964 1.00 25.20 ? 44 GLY B C 1 ATOM 1961 O O . GLY B 2 44 ? -22.544 -40.560 22.033 1.00 24.06 ? 44 GLY B O 1 ATOM 1962 N N . LEU B 2 45 ? -22.695 -38.519 21.078 1.00 20.55 ? 45 LEU B N 1 ATOM 1963 C CA . LEU B 2 45 ? -23.722 -38.915 20.110 1.00 19.16 ? 45 LEU B CA 1 ATOM 1964 C C . LEU B 2 45 ? -23.146 -39.756 18.973 1.00 19.74 ? 45 LEU B C 1 ATOM 1965 O O . LEU B 2 45 ? -22.122 -39.423 18.369 1.00 22.78 ? 45 LEU B O 1 ATOM 1966 C CB . LEU B 2 45 ? -24.445 -37.699 19.530 1.00 19.94 ? 45 LEU B CB 1 ATOM 1967 C CG . LEU B 2 45 ? -25.309 -36.872 20.485 1.00 19.98 ? 45 LEU B CG 1 ATOM 1968 C CD1 . LEU B 2 45 ? -25.502 -35.473 19.934 1.00 16.96 ? 45 LEU B CD1 1 ATOM 1969 C CD2 . LEU B 2 45 ? -26.646 -37.537 20.736 1.00 17.41 ? 45 LEU B CD2 1 ATOM 1970 N N . GLU B 2 46 ? -23.843 -40.833 18.668 1.00 21.37 ? 46 GLU B N 1 ATOM 1971 C CA . GLU B 2 46 ? -23.327 -41.848 17.792 1.00 19.91 ? 46 GLU B CA 1 ATOM 1972 C C . GLU B 2 46 ? -24.532 -42.442 17.086 1.00 20.56 ? 46 GLU B C 1 ATOM 1973 O O . GLU B 2 46 ? -25.448 -42.939 17.739 1.00 24.25 ? 46 GLU B O 1 ATOM 1974 C CB . GLU B 2 46 ? -22.636 -42.897 18.656 1.00 18.95 ? 46 GLU B CB 1 ATOM 1975 C CG . GLU B 2 46 ? -21.949 -44.019 17.933 1.00 21.35 ? 46 GLU B CG 1 ATOM 1976 C CD . GLU B 2 46 ? -21.173 -44.906 18.901 1.00 37.30 ? 46 GLU B CD 1 ATOM 1977 O OE1 . GLU B 2 46 ? -21.526 -44.942 20.107 1.00 33.65 ? 46 GLU B OE1 1 ATOM 1978 O OE2 . GLU B 2 46 ? -20.203 -45.559 18.461 1.00 43.64 ? 46 GLU B OE2 1 ATOM 1979 N N . TRP B 2 47 ? -24.559 -42.358 15.759 1.00 20.65 ? 47 TRP B N 1 ATOM 1980 C CA . TRP B 2 47 ? -25.650 -42.936 14.994 1.00 19.91 ? 47 TRP B CA 1 ATOM 1981 C C . TRP B 2 47 ? -25.432 -44.439 14.897 1.00 19.18 ? 47 TRP B C 1 ATOM 1982 O O . TRP B 2 47 ? -24.336 -44.883 14.586 1.00 25.78 ? 47 TRP B O 1 ATOM 1983 C CB . TRP B 2 47 ? -25.687 -42.291 13.612 1.00 25.33 ? 47 TRP B CB 1 ATOM 1984 C CG . TRP B 2 47 ? -26.759 -42.772 12.668 1.00 19.80 ? 47 TRP B CG 1 ATOM 1985 C CD1 . TRP B 2 47 ? -28.053 -42.343 12.606 1.00 18.78 ? 47 TRP B CD1 1 ATOM 1986 C CD2 . TRP B 2 47 ? -26.602 -43.730 11.613 1.00 18.83 ? 47 TRP B CD2 1 ATOM 1987 N NE1 . TRP B 2 47 ? -28.716 -42.990 11.591 1.00 19.70 ? 47 TRP B NE1 1 ATOM 1988 C CE2 . TRP B 2 47 ? -27.849 -43.843 10.965 1.00 20.61 ? 47 TRP B CE2 1 ATOM 1989 C CE3 . TRP B 2 47 ? -25.528 -44.509 11.160 1.00 21.79 ? 47 TRP B CE3 1 ATOM 1990 C CZ2 . TRP B 2 47 ? -28.054 -44.703 9.880 1.00 24.84 ? 47 TRP B CZ2 1 ATOM 1991 C CZ3 . TRP B 2 47 ? -25.728 -45.364 10.078 1.00 18.16 ? 47 TRP B CZ3 1 ATOM 1992 C CH2 . TRP B 2 47 ? -26.988 -45.456 9.454 1.00 24.21 ? 47 TRP B CH2 1 ATOM 1993 N N . LEU B 2 48 ? -26.468 -45.222 15.170 1.00 18.07 ? 48 LEU B N 1 ATOM 1994 C CA . LEU B 2 48 ? -26.344 -46.676 15.157 1.00 20.59 ? 48 LEU B CA 1 ATOM 1995 C C . LEU B 2 48 ? -26.903 -47.344 13.881 1.00 24.03 ? 48 LEU B C 1 ATOM 1996 O O . LEU B 2 48 ? -26.323 -48.293 13.358 1.00 20.92 ? 48 LEU B O 1 ATOM 1997 C CB . LEU B 2 48 ? -27.009 -47.255 16.407 1.00 20.01 ? 48 LEU B CB 1 ATOM 1998 C CG . LEU B 2 48 ? -26.476 -46.709 17.741 1.00 23.65 ? 48 LEU B CG 1 ATOM 1999 C CD1 . LEU B 2 48 ? -27.363 -47.108 18.921 1.00 18.95 ? 48 LEU B CD1 1 ATOM 2000 C CD2 . LEU B 2 48 ? -25.046 -47.161 17.991 1.00 19.30 ? 48 LEU B CD2 1 ATOM 2001 N N . GLY B 2 49 ? -28.033 -46.854 13.386 1.00 29.04 ? 49 GLY B N 1 ATOM 2002 C CA . GLY B 2 49 ? -28.637 -47.413 12.187 1.00 23.20 ? 49 GLY B CA 1 ATOM 2003 C C . GLY B 2 49 ? -30.039 -46.898 11.936 1.00 22.78 ? 49 GLY B C 1 ATOM 2004 O O . GLY B 2 49 ? -30.500 -45.973 12.596 1.00 24.00 ? 49 GLY B O 1 ATOM 2005 N N . VAL B 2 50 ? -30.730 -47.525 10.993 1.00 28.10 ? 50 VAL B N 1 ATOM 2006 C CA . VAL B 2 50 ? -32.012 -47.034 10.512 1.00 19.40 ? 50 VAL B CA 1 ATOM 2007 C C . VAL B 2 50 ? -32.780 -48.183 9.876 1.00 18.34 ? 50 VAL B C 1 ATOM 2008 O O . VAL B 2 50 ? -32.199 -49.041 9.234 1.00 24.10 ? 50 VAL B O 1 ATOM 2009 C CB . VAL B 2 50 ? -31.797 -45.906 9.472 1.00 17.76 ? 50 VAL B CB 1 ATOM 2010 C CG1 . VAL B 2 50 ? -30.745 -46.310 8.478 1.00 19.99 ? 50 VAL B CG1 1 ATOM 2011 C CG2 . VAL B 2 50 ? -33.092 -45.544 8.755 1.00 19.53 ? 50 VAL B CG2 1 ATOM 2012 N N . ILE B 2 51 ? -34.083 -48.236 10.102 1.00 26.12 ? 51 ILE B N 1 ATOM 2013 C CA . ILE B 2 51 ? -34.927 -49.109 9.313 1.00 21.84 ? 51 ILE B CA 1 ATOM 2014 C C . ILE B 2 51 ? -35.775 -48.237 8.402 1.00 25.99 ? 51 ILE B C 1 ATOM 2015 O O . ILE B 2 51 ? -36.445 -47.305 8.863 1.00 25.14 ? 51 ILE B O 1 ATOM 2016 C CB . ILE B 2 51 ? -35.777 -50.067 10.164 1.00 23.28 ? 51 ILE B CB 1 ATOM 2017 C CG1 . ILE B 2 51 ? -36.478 -51.083 9.255 1.00 23.07 ? 51 ILE B CG1 1 ATOM 2018 C CG2 . ILE B 2 51 ? -36.762 -49.314 11.063 1.00 21.24 ? 51 ILE B CG2 1 ATOM 2019 C CD1 . ILE B 2 51 ? -36.815 -52.400 9.948 1.00 18.04 ? 51 ILE B CD1 1 ATOM 2020 N N . TRP B 2 52 ? -35.693 -48.515 7.102 1.00 25.15 ? 52 TRP B N 1 ATOM 2021 C CA . TRP B 2 52 ? -36.335 -47.688 6.078 1.00 23.42 ? 52 TRP B CA 1 ATOM 2022 C C . TRP B 2 52 ? -37.783 -48.075 5.858 1.00 25.31 ? 52 TRP B C 1 ATOM 2023 O O . TRP B 2 52 ? -38.219 -49.160 6.242 1.00 24.57 ? 52 TRP B O 1 ATOM 2024 C CB . TRP B 2 52 ? -35.586 -47.799 4.746 1.00 24.16 ? 52 TRP B CB 1 ATOM 2025 C CG . TRP B 2 52 ? -34.205 -47.287 4.797 1.00 24.07 ? 52 TRP B CG 1 ATOM 2026 C CD1 . TRP B 2 52 ? -33.054 -48.018 4.715 1.00 26.10 ? 52 TRP B CD1 1 ATOM 2027 C CD2 . TRP B 2 52 ? -33.805 -45.926 4.976 1.00 26.11 ? 52 TRP B CD2 1 ATOM 2028 N NE1 . TRP B 2 52 ? -31.965 -47.196 4.828 1.00 23.04 ? 52 TRP B NE1 1 ATOM 2029 C CE2 . TRP B 2 52 ? -32.397 -45.903 4.974 1.00 26.07 ? 52 TRP B CE2 1 ATOM 2030 C CE3 . TRP B 2 52 ? -34.501 -44.719 5.123 1.00 26.02 ? 52 TRP B CE3 1 ATOM 2031 C CZ2 . TRP B 2 52 ? -31.668 -44.723 5.126 1.00 26.98 ? 52 TRP B CZ2 1 ATOM 2032 C CZ3 . TRP B 2 52 ? -33.782 -43.555 5.270 1.00 24.09 ? 52 TRP B CZ3 1 ATOM 2033 C CH2 . TRP B 2 52 ? -32.378 -43.561 5.275 1.00 22.88 ? 52 TRP B CH2 1 ATOM 2034 N N . SER B 2 53 ? -38.518 -47.183 5.205 1.00 36.67 ? 53 SER B N 1 ATOM 2035 C CA . SER B 2 53 ? -39.929 -47.409 4.880 1.00 32.63 ? 53 SER B CA 1 ATOM 2036 C C . SER B 2 53 ? -40.218 -48.813 4.356 1.00 32.34 ? 53 SER B C 1 ATOM 2037 O O . SER B 2 53 ? -41.128 -49.493 4.842 1.00 28.49 ? 53 SER B O 1 ATOM 2038 C CB . SER B 2 53 ? -40.385 -46.375 3.863 1.00 33.73 ? 53 SER B CB 1 ATOM 2039 O OG . SER B 2 53 ? -40.295 -45.082 4.424 1.00 36.31 ? 53 SER B OG 1 ATOM 2040 N N . GLY B 2 54 ? -39.423 -49.247 3.383 1.00 28.40 ? 54 GLY B N 1 ATOM 2041 C CA . GLY B 2 54 ? -39.624 -50.539 2.752 1.00 18.47 ? 54 GLY B CA 1 ATOM 2042 C C . GLY B 2 54 ? -39.042 -51.702 3.520 1.00 27.29 ? 54 GLY B C 1 ATOM 2043 O O . GLY B 2 54 ? -39.086 -52.837 3.047 1.00 29.72 ? 54 GLY B O 1 ATOM 2044 N N . GLY B 2 55 ? -38.476 -51.429 4.695 1.00 31.86 ? 55 GLY B N 1 ATOM 2045 C CA . GLY B 2 55 ? -37.967 -52.489 5.559 1.00 21.81 ? 55 GLY B CA 1 ATOM 2046 C C . GLY B 2 55 ? -36.474 -52.777 5.501 1.00 20.28 ? 55 GLY B C 1 ATOM 2047 O O . GLY B 2 55 ? -35.965 -53.585 6.271 1.00 30.36 ? 55 GLY B O 1 ATOM 2048 N N . ASN B 2 56 ? -35.769 -52.146 4.571 1.00 25.57 ? 56 ASN B N 1 ATOM 2049 C CA . ASN B 2 56 ? -34.320 -52.279 4.487 1.00 24.18 ? 56 ASN B CA 1 ATOM 2050 C C . ASN B 2 56 ? -33.651 -51.647 5.699 1.00 24.34 ? 56 ASN B C 1 ATOM 2051 O O . ASN B 2 56 ? -34.159 -50.670 6.256 1.00 24.14 ? 56 ASN B O 1 ATOM 2052 C CB . ASN B 2 56 ? -33.804 -51.590 3.224 1.00 32.96 ? 56 ASN B CB 1 ATOM 2053 C CG . ASN B 2 56 ? -34.146 -52.347 1.960 1.00 33.04 ? 56 ASN B CG 1 ATOM 2054 O OD1 . ASN B 2 56 ? -34.275 -53.574 1.970 1.00 29.55 ? 56 ASN B OD1 1 ATOM 2055 N ND2 . ASN B 2 56 ? -34.270 -51.619 0.853 1.00 32.05 ? 56 ASN B ND2 1 ATOM 2056 N N . THR B 2 57 ? -32.508 -52.186 6.105 1.00 22.19 ? 57 THR B N 1 ATOM 2057 C CA . THR B 2 57 ? -31.762 -51.586 7.202 1.00 21.56 ? 57 THR B CA 1 ATOM 2058 C C . THR B 2 57 ? -30.311 -51.288 6.846 1.00 18.29 ? 57 THR B C 1 ATOM 2059 O O . THR B 2 57 ? -29.702 -51.999 6.066 1.00 24.91 ? 57 THR B O 1 ATOM 2060 C CB . THR B 2 57 ? -31.771 -52.475 8.460 1.00 22.39 ? 57 THR B CB 1 ATOM 2061 O OG1 . THR B 2 57 ? -31.278 -53.779 8.133 1.00 19.27 ? 57 THR B OG1 1 ATOM 2062 C CG2 . THR B 2 57 ? -33.180 -52.585 9.035 1.00 22.85 ? 57 THR B CG2 1 ATOM 2063 N N . ASP B 2 58 ? -29.773 -50.220 7.421 1.00 18.81 ? 58 ASP B N 1 ATOM 2064 C CA . ASP B 2 58 ? -28.337 -49.973 7.421 1.00 20.69 ? 58 ASP B CA 1 ATOM 2065 C C . ASP B 2 58 ? -27.900 -49.925 8.866 1.00 27.37 ? 58 ASP B C 1 ATOM 2066 O O . ASP B 2 58 ? -28.633 -49.414 9.724 1.00 25.73 ? 58 ASP B O 1 ATOM 2067 C CB . ASP B 2 58 ? -28.007 -48.628 6.777 1.00 26.93 ? 58 ASP B CB 1 ATOM 2068 C CG . ASP B 2 58 ? -28.573 -48.496 5.378 1.00 29.50 ? 58 ASP B CG 1 ATOM 2069 O OD1 . ASP B 2 58 ? -28.564 -49.497 4.631 1.00 26.21 ? 58 ASP B OD1 1 ATOM 2070 O OD2 . ASP B 2 58 ? -29.032 -47.389 5.021 1.00 32.88 ? 58 ASP B OD2 1 ATOM 2071 N N . TYR B 2 59 ? -26.712 -50.444 9.148 1.00 26.09 ? 59 TYR B N 1 ATOM 2072 C CA . TYR B 2 59 ? -26.121 -50.299 10.478 1.00 22.86 ? 59 TYR B CA 1 ATOM 2073 C C . TYR B 2 59 ? -24.777 -49.604 10.385 1.00 19.95 ? 59 TYR B C 1 ATOM 2074 O O . TYR B 2 59 ? -23.978 -49.912 9.501 1.00 21.63 ? 59 TYR B O 1 ATOM 2075 C CB . TYR B 2 59 ? -25.956 -51.660 11.147 1.00 26.62 ? 59 TYR B CB 1 ATOM 2076 C CG . TYR B 2 59 ? -27.234 -52.437 11.180 1.00 19.08 ? 59 TYR B CG 1 ATOM 2077 C CD1 . TYR B 2 59 ? -28.401 -51.874 11.672 1.00 18.20 ? 59 TYR B CD1 1 ATOM 2078 C CD2 . TYR B 2 59 ? -27.280 -53.736 10.706 1.00 22.81 ? 59 TYR B CD2 1 ATOM 2079 C CE1 . TYR B 2 59 ? -29.586 -52.595 11.682 1.00 25.37 ? 59 TYR B CE1 1 ATOM 2080 C CE2 . TYR B 2 59 ? -28.457 -54.461 10.710 1.00 21.39 ? 59 TYR B CE2 1 ATOM 2081 C CZ . TYR B 2 59 ? -29.601 -53.893 11.198 1.00 21.54 ? 59 TYR B CZ 1 ATOM 2082 O OH . TYR B 2 59 ? -30.764 -54.630 11.189 1.00 27.66 ? 59 TYR B OH 1 ATOM 2083 N N . ASN B 2 60 ? -24.526 -48.665 11.289 1.00 16.96 ? 60 ASN B N 1 ATOM 2084 C CA . ASN B 2 60 ? -23.202 -48.056 11.376 1.00 22.48 ? 60 ASN B CA 1 ATOM 2085 C C . ASN B 2 60 ? -22.182 -49.187 11.488 1.00 21.53 ? 60 ASN B C 1 ATOM 2086 O O . ASN B 2 60 ? -22.491 -50.237 12.049 1.00 25.02 ? 60 ASN B O 1 ATOM 2087 C CB . ASN B 2 60 ? -23.102 -47.085 12.566 1.00 18.43 ? 60 ASN B CB 1 ATOM 2088 C CG . ASN B 2 60 ? -21.945 -46.109 12.422 1.00 23.64 ? 60 ASN B CG 1 ATOM 2089 O OD1 . ASN B 2 60 ? -21.118 -46.261 11.533 1.00 30.74 ? 60 ASN B OD1 1 ATOM 2090 N ND2 . ASN B 2 60 ? -21.876 -45.112 13.301 1.00 21.73 ? 60 ASN B ND2 1 ATOM 2091 N N . THR B 2 61 ? -20.994 -48.991 10.924 1.00 22.00 ? 61 THR B N 1 ATOM 2092 C CA . THR B 2 61 ? -20.016 -50.080 10.776 1.00 26.07 ? 61 THR B CA 1 ATOM 2093 C C . THR B 2 61 ? -19.729 -50.965 12.008 1.00 26.40 ? 61 THR B C 1 ATOM 2094 O O . THR B 2 61 ? -19.788 -52.192 11.909 1.00 27.39 ? 61 THR B O 1 ATOM 2095 C CB . THR B 2 61 ? -18.671 -49.568 10.238 1.00 31.01 ? 61 THR B CB 1 ATOM 2096 O OG1 . THR B 2 61 ? -18.908 -48.574 9.238 1.00 33.45 ? 61 THR B OG1 1 ATOM 2097 C CG2 . THR B 2 61 ? -17.872 -50.729 9.657 1.00 28.82 ? 61 THR B CG2 1 ATOM 2098 N N . PRO B 2 62 ? -19.421 -50.352 13.170 1.00 27.40 ? 62 PRO B N 1 ATOM 2099 C CA . PRO B 2 62 ? -19.069 -51.211 14.300 1.00 21.61 ? 62 PRO B CA 1 ATOM 2100 C C . PRO B 2 62 ? -20.235 -51.974 14.949 1.00 25.99 ? 62 PRO B C 1 ATOM 2101 O O . PRO B 2 62 ? -20.003 -52.653 15.950 1.00 33.57 ? 62 PRO B O 1 ATOM 2102 C CB . PRO B 2 62 ? -18.451 -50.228 15.294 1.00 26.56 ? 62 PRO B CB 1 ATOM 2103 C CG . PRO B 2 62 ? -19.092 -48.950 14.998 1.00 26.19 ? 62 PRO B CG 1 ATOM 2104 C CD . PRO B 2 62 ? -19.317 -48.923 13.523 1.00 21.04 ? 62 PRO B CD 1 ATOM 2105 N N . PHE B 2 63 ? -21.446 -51.889 14.403 1.00 22.28 ? 63 PHE B N 1 ATOM 2106 C CA . PHE B 2 63 ? -22.587 -52.595 14.992 1.00 23.10 ? 63 PHE B CA 1 ATOM 2107 C C . PHE B 2 63 ? -23.244 -53.529 13.973 1.00 30.65 ? 63 PHE B C 1 ATOM 2108 O O . PHE B 2 63 ? -24.284 -54.134 14.245 1.00 32.18 ? 63 PHE B O 1 ATOM 2109 C CB . PHE B 2 63 ? -23.613 -51.614 15.562 1.00 21.56 ? 63 PHE B CB 1 ATOM 2110 C CG . PHE B 2 63 ? -23.011 -50.532 16.407 1.00 22.72 ? 63 PHE B CG 1 ATOM 2111 C CD1 . PHE B 2 63 ? -22.684 -49.303 15.854 1.00 21.58 ? 63 PHE B CD1 1 ATOM 2112 C CD2 . PHE B 2 63 ? -22.773 -50.741 17.756 1.00 26.20 ? 63 PHE B CD2 1 ATOM 2113 C CE1 . PHE B 2 63 ? -22.118 -48.300 16.637 1.00 25.80 ? 63 PHE B CE1 1 ATOM 2114 C CE2 . PHE B 2 63 ? -22.213 -49.748 18.542 1.00 26.43 ? 63 PHE B CE2 1 ATOM 2115 C CZ . PHE B 2 63 ? -21.883 -48.528 17.986 1.00 29.06 ? 63 PHE B CZ 1 ATOM 2116 N N . THR B 2 64 ? -22.627 -53.624 12.800 1.00 28.98 ? 64 THR B N 1 ATOM 2117 C CA . THR B 2 64 ? -22.983 -54.596 11.766 1.00 29.79 ? 64 THR B CA 1 ATOM 2118 C C . THR B 2 64 ? -23.396 -55.959 12.329 1.00 34.55 ? 64 THR B C 1 ATOM 2119 O O . THR B 2 64 ? -24.447 -56.498 11.984 1.00 36.02 ? 64 THR B O 1 ATOM 2120 C CB . THR B 2 64 ? -21.756 -54.831 10.852 1.00 35.41 ? 64 THR B CB 1 ATOM 2121 O OG1 . THR B 2 64 ? -21.470 -53.640 10.109 1.00 37.87 ? 64 THR B OG1 1 ATOM 2122 C CG2 . THR B 2 64 ? -21.976 -56.001 9.901 1.00 33.80 ? 64 THR B CG2 1 ATOM 2123 N N . SER B 2 65 ? -22.567 -56.503 13.218 1.00 37.87 ? 65 SER B N 1 ATOM 2124 C CA . SER B 2 65 ? -22.708 -57.891 13.640 1.00 36.04 ? 65 SER B CA 1 ATOM 2125 C C . SER B 2 65 ? -23.401 -58.081 14.981 1.00 36.33 ? 65 SER B C 1 ATOM 2126 O O . SER B 2 65 ? -23.444 -59.193 15.502 1.00 38.49 ? 65 SER B O 1 ATOM 2127 C CB . SER B 2 65 ? -21.345 -58.574 13.686 1.00 35.60 ? 65 SER B CB 1 ATOM 2128 O OG . SER B 2 65 ? -20.602 -58.127 14.802 1.00 42.66 ? 65 SER B OG 1 ATOM 2129 N N . ARG B 2 66 ? -23.943 -57.019 15.557 1.00 37.82 ? 66 ARG B N 1 ATOM 2130 C CA . ARG B 2 66 ? -24.658 -57.209 16.804 1.00 38.22 ? 66 ARG B CA 1 ATOM 2131 C C . ARG B 2 66 ? -25.911 -56.366 16.905 1.00 33.52 ? 66 ARG B C 1 ATOM 2132 O O . ARG B 2 66 ? -26.562 -56.335 17.939 1.00 41.67 ? 66 ARG B O 1 ATOM 2133 C CB . ARG B 2 66 ? -23.739 -56.981 18.008 1.00 37.29 ? 66 ARG B CB 1 ATOM 2134 C CG . ARG B 2 66 ? -23.122 -55.601 18.105 1.00 33.19 ? 66 ARG B CG 1 ATOM 2135 C CD . ARG B 2 66 ? -22.521 -55.447 19.485 1.00 31.30 ? 66 ARG B CD 1 ATOM 2136 N NE . ARG B 2 66 ? -22.001 -54.114 19.742 1.00 32.48 ? 66 ARG B NE 1 ATOM 2137 C CZ . ARG B 2 66 ? -22.073 -53.521 20.929 1.00 31.39 ? 66 ARG B CZ 1 ATOM 2138 N NH1 . ARG B 2 66 ? -22.662 -54.145 21.941 1.00 22.21 ? 66 ARG B NH1 1 ATOM 2139 N NH2 . ARG B 2 66 ? -21.571 -52.305 21.099 1.00 27.71 ? 66 ARG B NH2 1 ATOM 2140 N N . LEU B 2 67 ? -26.265 -55.699 15.821 1.00 26.93 ? 67 LEU B N 1 ATOM 2141 C CA . LEU B 2 67 ? -27.467 -54.890 15.822 1.00 20.77 ? 67 LEU B CA 1 ATOM 2142 C C . LEU B 2 67 ? -28.505 -55.458 14.866 1.00 24.26 ? 67 LEU B C 1 ATOM 2143 O O . LEU B 2 67 ? -28.200 -55.819 13.731 1.00 36.61 ? 67 LEU B O 1 ATOM 2144 C CB . LEU B 2 67 ? -27.117 -53.445 15.462 1.00 25.32 ? 67 LEU B CB 1 ATOM 2145 C CG . LEU B 2 67 ? -28.218 -52.381 15.457 1.00 34.16 ? 67 LEU B CG 1 ATOM 2146 C CD1 . LEU B 2 67 ? -29.023 -52.481 16.736 1.00 29.33 ? 67 LEU B CD1 1 ATOM 2147 C CD2 . LEU B 2 67 ? -27.626 -50.974 15.294 1.00 23.25 ? 67 LEU B CD2 1 ATOM 2148 N N . SER B 2 68 ? -29.739 -55.555 15.328 1.00 23.65 ? 68 SER B N 1 ATOM 2149 C CA . SER B 2 68 ? -30.828 -55.900 14.441 1.00 20.24 ? 68 SER B CA 1 ATOM 2150 C C . SER B 2 68 ? -31.971 -54.932 14.682 1.00 25.19 ? 68 SER B C 1 ATOM 2151 O O . SER B 2 68 ? -32.309 -54.642 15.825 1.00 26.06 ? 68 SER B O 1 ATOM 2152 C CB . SER B 2 68 ? -31.274 -57.333 14.691 1.00 26.01 ? 68 SER B CB 1 ATOM 2153 O OG . SER B 2 68 ? -32.631 -57.379 15.095 1.00 35.68 ? 68 SER B OG 1 ATOM 2154 N N . ILE B 2 69 ? -32.555 -54.415 13.607 1.00 18.98 ? 69 ILE B N 1 ATOM 2155 C CA . ILE B 2 69 ? -33.724 -53.549 13.726 1.00 23.07 ? 69 ILE B CA 1 ATOM 2156 C C . ILE B 2 69 ? -34.900 -54.118 12.928 1.00 22.77 ? 69 ILE B C 1 ATOM 2157 O O . ILE B 2 69 ? -34.737 -54.538 11.786 1.00 26.45 ? 69 ILE B O 1 ATOM 2158 C CB . ILE B 2 69 ? -33.420 -52.102 13.248 1.00 27.79 ? 69 ILE B CB 1 ATOM 2159 C CG1 . ILE B 2 69 ? -32.168 -51.541 13.921 1.00 22.83 ? 69 ILE B CG1 1 ATOM 2160 C CG2 . ILE B 2 69 ? -34.597 -51.183 13.514 1.00 27.30 ? 69 ILE B CG2 1 ATOM 2161 C CD1 . ILE B 2 69 ? -31.753 -50.199 13.366 1.00 24.95 ? 69 ILE B CD1 1 ATOM 2162 N N . ASN B 2 70 ? -36.081 -54.145 13.537 1.00 26.93 ? 70 ASN B N 1 ATOM 2163 C CA . ASN B 2 70 ? -37.298 -54.593 12.855 1.00 24.71 ? 70 ASN B CA 1 ATOM 2164 C C . ASN B 2 70 ? -38.452 -53.683 13.200 1.00 30.10 ? 70 ASN B C 1 ATOM 2165 O O . ASN B 2 70 ? -38.331 -52.774 14.033 1.00 33.86 ? 70 ASN B O 1 ATOM 2166 C CB . ASN B 2 70 ? -37.682 -56.023 13.238 1.00 23.08 ? 70 ASN B CB 1 ATOM 2167 C CG . ASN B 2 70 ? -36.604 -57.024 12.908 1.00 28.62 ? 70 ASN B CG 1 ATOM 2168 O OD1 . ASN B 2 70 ? -35.571 -57.070 13.573 1.00 39.42 ? 70 ASN B OD1 1 ATOM 2169 N ND2 . ASN B 2 70 ? -36.833 -57.835 11.880 1.00 35.38 ? 70 ASN B ND2 1 ATOM 2170 N N . LYS B 2 71 ? -39.587 -53.937 12.571 1.00 22.85 ? 71 LYS B N 1 ATOM 2171 C CA . LYS B 2 71 ? -40.750 -53.128 12.830 1.00 29.25 ? 71 LYS B CA 1 ATOM 2172 C C . LYS B 2 71 ? -42.006 -53.885 12.483 1.00 33.18 ? 71 LYS B C 1 ATOM 2173 O O . LYS B 2 71 ? -41.957 -54.934 11.842 1.00 27.36 ? 71 LYS B O 1 ATOM 2174 C CB . LYS B 2 71 ? -40.683 -51.838 12.021 1.00 34.24 ? 71 LYS B CB 1 ATOM 2175 C CG . LYS B 2 71 ? -40.812 -52.056 10.531 1.00 29.77 ? 71 LYS B CG 1 ATOM 2176 C CD . LYS B 2 71 ? -40.560 -50.766 9.778 1.00 26.73 ? 71 LYS B CD 1 ATOM 2177 C CE . LYS B 2 71 ? -40.917 -50.904 8.311 1.00 23.77 ? 71 LYS B CE 1 ATOM 2178 N NZ . LYS B 2 71 ? -41.282 -49.569 7.797 1.00 24.62 ? 71 LYS B NZ 1 ATOM 2179 N N . ASP B 2 72 ? -43.126 -53.334 12.932 1.00 32.74 ? 72 ASP B N 1 ATOM 2180 C CA . ASP B 2 72 ? -44.448 -53.834 12.619 1.00 21.90 ? 72 ASP B CA 1 ATOM 2181 C C . ASP B 2 72 ? -45.219 -52.597 12.202 1.00 32.09 ? 72 ASP B C 1 ATOM 2182 O O . ASP B 2 72 ? -45.735 -51.872 13.054 1.00 37.65 ? 72 ASP B O 1 ATOM 2183 C CB . ASP B 2 72 ? -45.074 -54.467 13.865 1.00 35.90 ? 72 ASP B CB 1 ATOM 2184 C CG . ASP B 2 72 ? -46.457 -55.064 13.606 1.00 44.97 ? 72 ASP B CG 1 ATOM 2185 O OD1 . ASP B 2 72 ? -47.315 -54.401 12.973 1.00 39.30 ? 72 ASP B OD1 1 ATOM 2186 O OD2 . ASP B 2 72 ? -46.685 -56.210 14.054 1.00 45.08 ? 72 ASP B OD2 1 ATOM 2187 N N . ASN B 2 73 ? -45.274 -52.350 10.893 1.00 37.90 ? 73 ASN B N 1 ATOM 2188 C CA . ASN B 2 73 ? -45.955 -51.181 10.333 1.00 32.27 ? 73 ASN B CA 1 ATOM 2189 C C . ASN B 2 73 ? -47.352 -50.955 10.892 1.00 39.39 ? 73 ASN B C 1 ATOM 2190 O O . ASN B 2 73 ? -47.716 -49.822 11.236 1.00 36.06 ? 73 ASN B O 1 ATOM 2191 C CB . ASN B 2 73 ? -46.038 -51.278 8.812 1.00 31.23 ? 73 ASN B CB 1 ATOM 2192 C CG . ASN B 2 73 ? -44.726 -50.974 8.142 1.00 37.99 ? 73 ASN B CG 1 ATOM 2193 O OD1 . ASN B 2 73 ? -43.887 -50.269 8.699 1.00 33.58 ? 73 ASN B OD1 1 ATOM 2194 N ND2 . ASN B 2 73 ? -44.533 -51.509 6.940 1.00 36.68 ? 73 ASN B ND2 1 ATOM 2195 N N . SER B 2 74 ? -48.124 -52.036 10.985 1.00 42.23 ? 74 SER B N 1 ATOM 2196 C CA . SER B 2 74 ? -49.506 -51.959 11.446 1.00 38.97 ? 74 SER B CA 1 ATOM 2197 C C . SER B 2 74 ? -49.599 -51.505 12.898 1.00 38.48 ? 74 SER B C 1 ATOM 2198 O O . SER B 2 74 ? -50.492 -50.725 13.251 1.00 42.99 ? 74 SER B O 1 ATOM 2199 C CB . SER B 2 74 ? -50.236 -53.293 11.232 1.00 40.64 ? 74 SER B CB 1 ATOM 2200 O OG . SER B 2 74 ? -49.432 -54.400 11.591 1.00 44.83 ? 74 SER B OG 1 ATOM 2201 N N . LYS B 2 75 ? -48.657 -51.918 13.712 1.00 34.30 ? 75 LYS B N 1 ATOM 2202 C CA . LYS B 2 75 ? -48.665 -51.539 15.099 1.00 33.68 ? 75 LYS B CA 1 ATOM 2203 C C . LYS B 2 75 ? -47.898 -50.269 15.362 1.00 38.17 ? 75 LYS B C 1 ATOM 2204 O O . LYS B 2 75 ? -47.829 -49.806 16.477 1.00 34.02 ? 75 LYS B O 1 ATOM 2205 C CB . LYS B 2 75 ? -48.136 -52.654 15.933 1.00 30.36 ? 75 LYS B CB 1 ATOM 2206 C CG . LYS B 2 75 ? -49.168 -53.716 16.139 1.00 45.11 ? 75 LYS B CG 1 ATOM 2207 C CD . LYS B 2 75 ? -48.581 -55.100 16.143 1.00 47.88 ? 75 LYS B CD 1 ATOM 2208 C CE . LYS B 2 75 ? -47.915 -55.427 17.453 1.00 53.81 ? 75 LYS B CE 1 ATOM 2209 N NZ . LYS B 2 75 ? -47.924 -56.888 17.705 1.00 62.77 ? 75 LYS B NZ 1 ATOM 2210 N N . SER B 2 76 ? -47.338 -49.722 14.297 1.00 31.47 ? 76 SER B N 1 ATOM 2211 C CA . SER B 2 76 ? -46.521 -48.516 14.368 1.00 32.45 ? 76 SER B CA 1 ATOM 2212 C C . SER B 2 76 ? -45.342 -48.679 15.326 1.00 32.37 ? 76 SER B C 1 ATOM 2213 O O . SER B 2 76 ? -44.945 -47.726 15.998 1.00 30.07 ? 76 SER B O 1 ATOM 2214 C CB . SER B 2 76 ? -47.357 -47.303 14.776 1.00 27.62 ? 76 SER B CB 1 ATOM 2215 O OG . SER B 2 76 ? -48.158 -46.839 13.705 1.00 34.33 ? 76 SER B OG 1 ATOM 2216 N N . GLN B 2 77 ? -44.781 -49.881 15.381 1.00 27.25 ? 77 GLN B N 1 ATOM 2217 C CA . GLN B 2 77 ? -43.703 -50.156 16.316 1.00 32.17 ? 77 GLN B CA 1 ATOM 2218 C C . GLN B 2 77 ? -42.412 -50.491 15.604 1.00 31.84 ? 77 GLN B C 1 ATOM 2219 O O . GLN B 2 77 ? -42.407 -51.215 14.615 1.00 28.83 ? 77 GLN B O 1 ATOM 2220 C CB . GLN B 2 77 ? -44.082 -51.290 17.269 1.00 30.52 ? 77 GLN B CB 1 ATOM 2221 C CG . GLN B 2 77 ? -45.205 -50.929 18.223 1.00 31.18 ? 77 GLN B CG 1 ATOM 2222 C CD . GLN B 2 77 ? -45.686 -52.121 19.038 1.00 37.50 ? 77 GLN B CD 1 ATOM 2223 O OE1 . GLN B 2 77 ? -46.092 -51.975 20.194 1.00 33.03 ? 77 GLN B OE1 1 ATOM 2224 N NE2 . GLN B 2 77 ? -45.651 -53.304 18.433 1.00 34.28 ? 77 GLN B NE2 1 ATOM 2225 N N . VAL B 2 78 ? -41.315 -49.954 16.124 1.00 34.73 ? 78 VAL B N 1 ATOM 2226 C CA . VAL B 2 78 ? -39.987 -50.264 15.615 1.00 29.38 ? 78 VAL B CA 1 ATOM 2227 C C . VAL B 2 78 ? -39.178 -50.921 16.731 1.00 32.16 ? 78 VAL B C 1 ATOM 2228 O O . VAL B 2 78 ? -39.089 -50.374 17.841 1.00 28.57 ? 78 VAL B O 1 ATOM 2229 C CB . VAL B 2 78 ? -39.272 -49.001 15.124 1.00 21.60 ? 78 VAL B CB 1 ATOM 2230 C CG1 . VAL B 2 78 ? -37.834 -49.322 14.712 1.00 20.69 ? 78 VAL B CG1 1 ATOM 2231 C CG2 . VAL B 2 78 ? -40.039 -48.387 13.981 1.00 22.80 ? 78 VAL B CG2 1 ATOM 2232 N N . PHE B 2 79 ? -38.595 -52.085 16.447 1.00 22.87 ? 79 PHE B N 1 ATOM 2233 C CA . PHE B 2 79 ? -37.855 -52.821 17.473 1.00 27.06 ? 79 PHE B CA 1 ATOM 2234 C C . PHE B 2 79 ? -36.351 -52.798 17.258 1.00 25.20 ? 79 PHE B C 1 ATOM 2235 O O . PHE B 2 79 ? -35.855 -53.151 16.200 1.00 26.91 ? 79 PHE B O 1 ATOM 2236 C CB . PHE B 2 79 ? -38.308 -54.279 17.561 1.00 29.36 ? 79 PHE B CB 1 ATOM 2237 C CG . PHE B 2 79 ? -39.785 -54.457 17.511 1.00 28.93 ? 79 PHE B CG 1 ATOM 2238 C CD1 . PHE B 2 79 ? -40.396 -54.907 16.346 1.00 26.62 ? 79 PHE B CD1 1 ATOM 2239 C CD2 . PHE B 2 79 ? -40.569 -54.176 18.617 1.00 30.17 ? 79 PHE B CD2 1 ATOM 2240 C CE1 . PHE B 2 79 ? -41.769 -55.073 16.289 1.00 34.17 ? 79 PHE B CE1 1 ATOM 2241 C CE2 . PHE B 2 79 ? -41.945 -54.338 18.568 1.00 29.72 ? 79 PHE B CE2 1 ATOM 2242 C CZ . PHE B 2 79 ? -42.547 -54.787 17.409 1.00 31.64 ? 79 PHE B CZ 1 ATOM 2243 N N . PHE B 2 80 ? -35.635 -52.423 18.306 1.00 27.63 ? 80 PHE B N 1 ATOM 2244 C CA . PHE B 2 80 ? -34.193 -52.312 18.285 1.00 25.06 ? 80 PHE B CA 1 ATOM 2245 C C . PHE B 2 80 ? -33.647 -53.393 19.208 1.00 27.34 ? 80 PHE B C 1 ATOM 2246 O O . PHE B 2 80 ? -34.064 -53.510 20.365 1.00 32.78 ? 80 PHE B O 1 ATOM 2247 C CB . PHE B 2 80 ? -33.829 -50.910 18.787 1.00 26.10 ? 80 PHE B CB 1 ATOM 2248 C CG . PHE B 2 80 ? -32.359 -50.676 19.039 1.00 26.44 ? 80 PHE B CG 1 ATOM 2249 C CD1 . PHE B 2 80 ? -31.570 -50.083 18.077 1.00 17.44 ? 80 PHE B CD1 1 ATOM 2250 C CD2 . PHE B 2 80 ? -31.792 -50.969 20.274 1.00 24.61 ? 80 PHE B CD2 1 ATOM 2251 C CE1 . PHE B 2 80 ? -30.234 -49.826 18.320 1.00 21.83 ? 80 PHE B CE1 1 ATOM 2252 C CE2 . PHE B 2 80 ? -30.451 -50.715 20.523 1.00 23.20 ? 80 PHE B CE2 1 ATOM 2253 C CZ . PHE B 2 80 ? -29.671 -50.143 19.547 1.00 23.49 ? 80 PHE B CZ 1 ATOM 2254 N N . LYS B 2 81 ? -32.730 -54.196 18.690 1.00 25.25 ? 81 LYS B N 1 ATOM 2255 C CA . LYS B 2 81 ? -32.057 -55.207 19.491 1.00 23.26 ? 81 LYS B CA 1 ATOM 2256 C C . LYS B 2 81 ? -30.555 -55.138 19.250 1.00 28.44 ? 81 LYS B C 1 ATOM 2257 O O . LYS B 2 81 ? -30.099 -54.997 18.110 1.00 26.96 ? 81 LYS B O 1 ATOM 2258 C CB . LYS B 2 81 ? -32.592 -56.618 19.200 1.00 23.32 ? 81 LYS B CB 1 ATOM 2259 C CG . LYS B 2 81 ? -31.976 -57.702 20.095 1.00 32.78 ? 81 LYS B CG 1 ATOM 2260 C CD . LYS B 2 81 ? -32.658 -59.062 19.942 1.00 33.45 ? 81 LYS B CD 1 ATOM 2261 C CE . LYS B 2 81 ? -32.241 -60.018 21.058 1.00 39.79 ? 81 LYS B CE 1 ATOM 2262 N NZ . LYS B 2 81 ? -31.494 -61.215 20.560 1.00 56.12 ? 81 LYS B NZ 1 ATOM 2263 N N . MET B 2 82 ? -29.788 -55.219 20.330 1.00 27.70 ? 82 MET B N 1 ATOM 2264 C CA . MET B 2 82 ? -28.340 -55.208 20.217 1.00 29.98 ? 82 MET B CA 1 ATOM 2265 C C . MET B 2 82 ? -27.749 -56.235 21.172 1.00 30.88 ? 82 MET B C 1 ATOM 2266 O O . MET B 2 82 ? -28.005 -56.191 22.372 1.00 33.94 ? 82 MET B O 1 ATOM 2267 C CB . MET B 2 82 ? -27.771 -53.811 20.494 1.00 29.29 ? 82 MET B CB 1 ATOM 2268 C CG . MET B 2 82 ? -26.288 -53.666 20.156 1.00 30.04 ? 82 MET B CG 1 ATOM 2269 S SD . MET B 2 82 ? -25.649 -52.001 20.470 1.00 37.46 ? 82 MET B SD 1 ATOM 2270 C CE . MET B 2 82 ? -25.833 -51.921 22.253 1.00 30.87 ? 82 MET B CE 1 ATOM 2271 N N . ASN B 2 83 ? -26.962 -57.155 20.623 1.00 25.39 ? 83 ASN B N 1 ATOM 2272 C CA . ASN B 2 83 ? -26.433 -58.291 21.366 1.00 31.89 ? 83 ASN B CA 1 ATOM 2273 C C . ASN B 2 83 ? -25.153 -57.986 22.140 1.00 34.20 ? 83 ASN B C 1 ATOM 2274 O O . ASN B 2 83 ? -24.445 -57.011 21.853 1.00 29.06 ? 83 ASN B O 1 ATOM 2275 C CB . ASN B 2 83 ? -26.186 -59.473 20.416 1.00 28.56 ? 83 ASN B CB 1 ATOM 2276 C CG . ASN B 2 83 ? -27.453 -59.924 19.705 1.00 44.82 ? 83 ASN B CG 1 ATOM 2277 O OD1 . ASN B 2 83 ? -28.368 -60.476 20.331 1.00 49.55 ? 83 ASN B OD1 1 ATOM 2278 N ND2 . ASN B 2 83 ? -27.512 -59.702 18.388 1.00 50.25 ? 83 ASN B ND2 1 ATOM 2279 N N . SER B 2 84 ? -24.887 -58.851 23.116 1.00 29.85 ? 84 SER B N 1 ATOM 2280 C CA . SER B 2 84 ? -23.687 -58.834 23.955 1.00 37.58 ? 84 SER B CA 1 ATOM 2281 C C . SER B 2 84 ? -23.187 -57.449 24.377 1.00 37.14 ? 84 SER B C 1 ATOM 2282 O O . SER B 2 84 ? -22.191 -56.947 23.839 1.00 33.56 ? 84 SER B O 1 ATOM 2283 C CB . SER B 2 84 ? -22.563 -59.631 23.288 1.00 39.80 ? 84 SER B CB 1 ATOM 2284 O OG . SER B 2 84 ? -22.160 -59.008 22.090 1.00 44.07 ? 84 SER B OG 1 ATOM 2285 N N . LEU B 2 85 ? -23.871 -56.845 25.345 1.00 31.09 ? 85 LEU B N 1 ATOM 2286 C CA . LEU B 2 85 ? -23.498 -55.512 25.807 1.00 36.55 ? 85 LEU B CA 1 ATOM 2287 C C . LEU B 2 85 ? -22.333 -55.547 26.789 1.00 39.07 ? 85 LEU B C 1 ATOM 2288 O O . LEU B 2 85 ? -22.124 -56.537 27.496 1.00 36.26 ? 85 LEU B O 1 ATOM 2289 C CB . LEU B 2 85 ? -24.697 -54.791 26.417 1.00 31.74 ? 85 LEU B CB 1 ATOM 2290 C CG . LEU B 2 85 ? -25.482 -53.913 25.437 1.00 38.74 ? 85 LEU B CG 1 ATOM 2291 C CD1 . LEU B 2 85 ? -26.253 -54.754 24.437 1.00 34.05 ? 85 LEU B CD1 1 ATOM 2292 C CD2 . LEU B 2 85 ? -26.421 -52.944 26.155 1.00 30.76 ? 85 LEU B CD2 1 ATOM 2293 N N . GLN B 2 86 ? -21.561 -54.471 26.816 1.00 31.14 ? 86 GLN B N 1 ATOM 2294 C CA . GLN B 2 86 ? -20.490 -54.339 27.790 1.00 31.32 ? 86 GLN B CA 1 ATOM 2295 C C . GLN B 2 86 ? -20.685 -53.016 28.491 1.00 37.65 ? 86 GLN B C 1 ATOM 2296 O O . GLN B 2 86 ? -21.577 -52.250 28.130 1.00 37.30 ? 86 GLN B O 1 ATOM 2297 C CB . GLN B 2 86 ? -19.118 -54.390 27.119 1.00 34.44 ? 86 GLN B CB 1 ATOM 2298 C CG . GLN B 2 86 ? -18.839 -55.695 26.373 1.00 51.01 ? 86 GLN B CG 1 ATOM 2299 C CD . GLN B 2 86 ? -19.057 -56.942 27.233 1.00 49.91 ? 86 GLN B CD 1 ATOM 2300 O OE1 . GLN B 2 86 ? -18.866 -56.921 28.457 1.00 46.30 ? 86 GLN B OE1 1 ATOM 2301 N NE2 . GLN B 2 86 ? -19.469 -58.034 26.590 1.00 48.22 ? 86 GLN B NE2 1 ATOM 2302 N N . SER B 2 87 ? -19.863 -52.749 29.495 1.00 32.40 ? 87 SER B N 1 ATOM 2303 C CA . SER B 2 87 ? -20.013 -51.528 30.260 1.00 37.88 ? 87 SER B CA 1 ATOM 2304 C C . SER B 2 87 ? -20.065 -50.267 29.409 1.00 29.11 ? 87 SER B C 1 ATOM 2305 O O . SER B 2 87 ? -20.884 -49.397 29.652 1.00 28.04 ? 87 SER B O 1 ATOM 2306 C CB . SER B 2 87 ? -18.939 -51.421 31.343 1.00 37.56 ? 87 SER B CB 1 ATOM 2307 O OG . SER B 2 87 ? -19.371 -52.087 32.517 1.00 52.94 ? 87 SER B OG 1 ATOM 2308 N N . ASN B 2 88 ? -19.220 -50.163 28.396 1.00 31.27 ? 88 ASN B N 1 ATOM 2309 C CA . ASN B 2 88 ? -19.248 -48.940 27.604 1.00 29.77 ? 88 ASN B CA 1 ATOM 2310 C C . ASN B 2 88 ? -20.442 -48.847 26.650 1.00 28.11 ? 88 ASN B C 1 ATOM 2311 O O . ASN B 2 88 ? -20.535 -47.926 25.855 1.00 32.54 ? 88 ASN B O 1 ATOM 2312 C CB . ASN B 2 88 ? -17.916 -48.670 26.898 1.00 29.93 ? 88 ASN B CB 1 ATOM 2313 C CG . ASN B 2 88 ? -17.545 -49.734 25.898 1.00 40.81 ? 88 ASN B CG 1 ATOM 2314 O OD1 . ASN B 2 88 ? -18.356 -50.590 25.534 1.00 40.84 ? 88 ASN B OD1 1 ATOM 2315 N ND2 . ASN B 2 88 ? -16.289 -49.682 25.439 1.00 51.39 ? 88 ASN B ND2 1 ATOM 2316 N N . ASP B 2 89 ? -21.366 -49.797 26.735 1.00 29.87 ? 89 ASP B N 1 ATOM 2317 C CA . ASP B 2 89 ? -22.613 -49.681 25.989 1.00 26.34 ? 89 ASP B CA 1 ATOM 2318 C C . ASP B 2 89 ? -23.682 -49.020 26.845 1.00 25.35 ? 89 ASP B C 1 ATOM 2319 O O . ASP B 2 89 ? -24.819 -48.841 26.418 1.00 20.95 ? 89 ASP B O 1 ATOM 2320 C CB . ASP B 2 89 ? -23.075 -51.035 25.462 1.00 27.79 ? 89 ASP B CB 1 ATOM 2321 C CG . ASP B 2 89 ? -22.153 -51.579 24.390 1.00 31.36 ? 89 ASP B CG 1 ATOM 2322 O OD1 . ASP B 2 89 ? -21.772 -50.793 23.489 1.00 32.32 ? 89 ASP B OD1 1 ATOM 2323 O OD2 . ASP B 2 89 ? -21.800 -52.778 24.460 1.00 29.33 ? 89 ASP B OD2 1 ATOM 2324 N N . THR B 2 90 ? -23.294 -48.651 28.060 1.00 26.82 ? 90 THR B N 1 ATOM 2325 C CA . THR B 2 90 ? -24.145 -47.833 28.902 1.00 27.36 ? 90 THR B CA 1 ATOM 2326 C C . THR B 2 90 ? -24.326 -46.507 28.197 1.00 24.52 ? 90 THR B C 1 ATOM 2327 O O . THR B 2 90 ? -23.353 -45.804 27.930 1.00 24.51 ? 90 THR B O 1 ATOM 2328 C CB . THR B 2 90 ? -23.520 -47.589 30.293 1.00 22.38 ? 90 THR B CB 1 ATOM 2329 O OG1 . THR B 2 90 ? -23.437 -48.836 30.998 1.00 26.15 ? 90 THR B OG1 1 ATOM 2330 C CG2 . THR B 2 90 ? -24.361 -46.587 31.096 1.00 14.74 ? 90 THR B CG2 1 ATOM 2331 N N . ALA B 2 91 ? -25.576 -46.177 27.891 1.00 21.50 ? 91 ALA B N 1 ATOM 2332 C CA . ALA B 2 91 ? -25.885 -44.955 27.169 1.00 19.67 ? 91 ALA B CA 1 ATOM 2333 C C . ALA B 2 91 ? -27.375 -44.653 27.226 1.00 22.60 ? 91 ALA B C 1 ATOM 2334 O O . ALA B 2 91 ? -28.178 -45.483 27.678 1.00 19.47 ? 91 ALA B O 1 ATOM 2335 C CB . ALA B 2 91 ? -25.441 -45.092 25.719 1.00 21.06 ? 91 ALA B CB 1 ATOM 2336 N N . ILE B 2 92 ? -27.737 -43.454 26.779 1.00 16.15 ? 92 ILE B N 1 ATOM 2337 C CA . ILE B 2 92 ? -29.123 -43.166 26.471 1.00 20.88 ? 92 ILE B CA 1 ATOM 2338 C C . ILE B 2 92 ? -29.339 -43.478 24.997 1.00 19.25 ? 92 ILE B C 1 ATOM 2339 O O . ILE B 2 92 ? -28.671 -42.915 24.130 1.00 17.82 ? 92 ILE B O 1 ATOM 2340 C CB . ILE B 2 92 ? -29.494 -41.700 26.703 1.00 17.11 ? 92 ILE B CB 1 ATOM 2341 C CG1 . ILE B 2 92 ? -29.235 -41.299 28.145 1.00 17.21 ? 92 ILE B CG1 1 ATOM 2342 C CG2 . ILE B 2 92 ? -30.951 -41.469 26.338 1.00 17.98 ? 92 ILE B CG2 1 ATOM 2343 C CD1 . ILE B 2 92 ? -29.150 -39.808 28.321 1.00 22.81 ? 92 ILE B CD1 1 ATOM 2344 N N . TYR B 2 93 ? -30.270 -44.383 24.729 1.00 17.19 ? 93 TYR B N 1 ATOM 2345 C CA . TYR B 2 93 ? -30.621 -44.760 23.378 1.00 18.09 ? 93 TYR B CA 1 ATOM 2346 C C . TYR B 2 93 ? -31.852 -43.990 22.921 1.00 21.77 ? 93 TYR B C 1 ATOM 2347 O O . TYR B 2 93 ? -32.783 -43.770 23.698 1.00 24.56 ? 93 TYR B O 1 ATOM 2348 C CB . TYR B 2 93 ? -30.850 -46.269 23.312 1.00 15.44 ? 93 TYR B CB 1 ATOM 2349 C CG . TYR B 2 93 ? -29.572 -47.026 23.519 1.00 19.80 ? 93 TYR B CG 1 ATOM 2350 C CD1 . TYR B 2 93 ? -29.053 -47.219 24.793 1.00 20.32 ? 93 TYR B CD1 1 ATOM 2351 C CD2 . TYR B 2 93 ? -28.852 -47.510 22.441 1.00 18.12 ? 93 TYR B CD2 1 ATOM 2352 C CE1 . TYR B 2 93 ? -27.859 -47.891 24.982 1.00 22.89 ? 93 TYR B CE1 1 ATOM 2353 C CE2 . TYR B 2 93 ? -27.671 -48.181 22.620 1.00 17.58 ? 93 TYR B CE2 1 ATOM 2354 C CZ . TYR B 2 93 ? -27.173 -48.367 23.883 1.00 22.71 ? 93 TYR B CZ 1 ATOM 2355 O OH . TYR B 2 93 ? -25.980 -49.043 24.037 1.00 28.04 ? 93 TYR B OH 1 ATOM 2356 N N . TYR B 2 94 ? -31.851 -43.574 21.659 1.00 19.67 ? 94 TYR B N 1 ATOM 2357 C CA . TYR B 2 94 ? -32.961 -42.804 21.115 1.00 21.65 ? 94 TYR B CA 1 ATOM 2358 C C . TYR B 2 94 ? -33.433 -43.368 19.801 1.00 21.20 ? 94 TYR B C 1 ATOM 2359 O O . TYR B 2 94 ? -32.645 -43.931 19.043 1.00 22.82 ? 94 TYR B O 1 ATOM 2360 C CB . TYR B 2 94 ? -32.536 -41.374 20.808 1.00 17.17 ? 94 TYR B CB 1 ATOM 2361 C CG . TYR B 2 94 ? -32.045 -40.536 21.945 1.00 17.16 ? 94 TYR B CG 1 ATOM 2362 C CD1 . TYR B 2 94 ? -32.898 -39.670 22.612 1.00 17.12 ? 94 TYR B CD1 1 ATOM 2363 C CD2 . TYR B 2 94 ? -30.710 -40.545 22.305 1.00 20.68 ? 94 TYR B CD2 1 ATOM 2364 C CE1 . TYR B 2 94 ? -32.439 -38.860 23.630 1.00 15.59 ? 94 TYR B CE1 1 ATOM 2365 C CE2 . TYR B 2 94 ? -30.241 -39.732 23.326 1.00 20.70 ? 94 TYR B CE2 1 ATOM 2366 C CZ . TYR B 2 94 ? -31.110 -38.896 23.981 1.00 15.51 ? 94 TYR B CZ 1 ATOM 2367 O OH . TYR B 2 94 ? -30.640 -38.102 24.998 1.00 26.97 ? 94 TYR B OH 1 ATOM 2368 N N . CYS B 2 95 ? -34.711 -43.165 19.502 1.00 19.55 ? 95 CYS B N 1 ATOM 2369 C CA . CYS B 2 95 ? -35.183 -43.340 18.131 1.00 21.41 ? 95 CYS B CA 1 ATOM 2370 C C . CYS B 2 95 ? -35.522 -41.964 17.554 1.00 21.75 ? 95 CYS B C 1 ATOM 2371 O O . CYS B 2 95 ? -35.923 -41.046 18.280 1.00 21.23 ? 95 CYS B O 1 ATOM 2372 C CB . CYS B 2 95 ? -36.354 -44.329 18.034 1.00 22.83 ? 95 CYS B CB 1 ATOM 2373 S SG . CYS B 2 95 ? -37.844 -43.867 18.940 1.00 30.22 ? 95 CYS B SG 1 ATOM 2374 N N . ALA B 2 96 ? -35.325 -41.803 16.257 1.00 16.62 ? 96 ALA B N 1 ATOM 2375 C CA . ALA B 2 96 ? -35.531 -40.498 15.663 1.00 16.04 ? 96 ALA B CA 1 ATOM 2376 C C . ALA B 2 96 ? -36.162 -40.604 14.296 1.00 21.73 ? 96 ALA B C 1 ATOM 2377 O O . ALA B 2 96 ? -36.083 -41.652 13.647 1.00 20.83 ? 96 ALA B O 1 ATOM 2378 C CB . ALA B 2 96 ? -34.228 -39.750 15.579 1.00 15.49 ? 96 ALA B CB 1 ATOM 2379 N N . ARG B 2 97 ? -36.799 -39.513 13.873 1.00 22.11 ? 97 ARG B N 1 ATOM 2380 C CA . ARG B 2 97 ? -37.342 -39.415 12.534 1.00 20.96 ? 97 ARG B CA 1 ATOM 2381 C C . ARG B 2 97 ? -36.821 -38.155 11.872 1.00 26.82 ? 97 ARG B C 1 ATOM 2382 O O . ARG B 2 97 ? -36.669 -37.118 12.518 1.00 23.28 ? 97 ARG B O 1 ATOM 2383 C CB . ARG B 2 97 ? -38.864 -39.396 12.544 1.00 19.77 ? 97 ARG B CB 1 ATOM 2384 C CG . ARG B 2 97 ? -39.466 -39.900 11.250 1.00 22.22 ? 97 ARG B CG 1 ATOM 2385 C CD . ARG B 2 97 ? -40.798 -39.250 10.958 1.00 25.34 ? 97 ARG B CD 1 ATOM 2386 N NE . ARG B 2 97 ? -40.627 -37.973 10.277 1.00 28.52 ? 97 ARG B NE 1 ATOM 2387 C CZ . ARG B 2 97 ? -41.628 -37.205 9.871 1.00 26.79 ? 97 ARG B CZ 1 ATOM 2388 N NH1 . ARG B 2 97 ? -42.879 -37.581 10.096 1.00 31.60 ? 97 ARG B NH1 1 ATOM 2389 N NH2 . ARG B 2 97 ? -41.378 -36.066 9.238 1.00 29.25 ? 97 ARG B NH2 1 ATOM 2390 N N . ALA B 2 98 ? -36.542 -38.254 10.576 1.00 27.91 ? 98 ALA B N 1 ATOM 2391 C CA . ALA B 2 98 ? -36.024 -37.125 9.827 1.00 25.54 ? 98 ALA B CA 1 ATOM 2392 C C . ALA B 2 98 ? -37.163 -36.249 9.313 1.00 23.55 ? 98 ALA B C 1 ATOM 2393 O O . ALA B 2 98 ? -38.331 -36.628 9.397 1.00 24.86 ? 98 ALA B O 1 ATOM 2394 C CB . ALA B 2 98 ? -35.144 -37.615 8.685 1.00 19.40 ? 98 ALA B CB 1 ATOM 2395 N N . LEU B 2 99 ? -36.825 -35.086 8.761 1.00 21.57 ? 99 LEU B N 1 ATOM 2396 C CA . LEU B 2 99 ? -37.815 -34.235 8.089 1.00 29.47 ? 99 LEU B CA 1 ATOM 2397 C C . LEU B 2 99 ? -38.428 -34.891 6.845 1.00 31.81 ? 99 LEU B C 1 ATOM 2398 O O . LEU B 2 99 ? -39.641 -34.841 6.651 1.00 33.03 ? 99 LEU B O 1 ATOM 2399 C CB . LEU B 2 99 ? -37.200 -32.895 7.695 1.00 23.18 ? 99 LEU B CB 1 ATOM 2400 C CG . LEU B 2 99 ? -37.236 -31.756 8.708 1.00 29.08 ? 99 LEU B CG 1 ATOM 2401 C CD1 . LEU B 2 99 ? -36.693 -30.509 8.057 1.00 25.42 ? 99 LEU B CD1 1 ATOM 2402 C CD2 . LEU B 2 99 ? -38.642 -31.513 9.255 1.00 18.98 ? 99 LEU B CD2 1 ATOM 2403 N N . THR B 2 100 ? -37.590 -35.489 5.999 1.00 32.18 ? 100 THR B N 1 ATOM 2404 C CA . THR B 2 100 ? -38.076 -36.166 4.798 1.00 29.05 ? 100 THR B CA 1 ATOM 2405 C C . THR B 2 100 ? -37.774 -37.652 4.891 1.00 26.91 ? 100 THR B C 1 ATOM 2406 O O . THR B 2 100 ? -36.998 -38.077 5.749 1.00 28.93 ? 100 THR B O 1 ATOM 2407 C CB . THR B 2 100 ? -37.474 -35.565 3.516 1.00 37.00 ? 100 THR B CB 1 ATOM 2408 O OG1 . THR B 2 100 ? -36.049 -35.579 3.613 1.00 45.18 ? 100 THR B OG1 1 ATOM 2409 C CG2 . THR B 2 100 ? -37.929 -34.132 3.346 1.00 40.31 ? 100 THR B CG2 1 ATOM 2410 N N . TYR B 2 101 ? -38.400 -38.442 4.030 1.00 24.66 ? 101 TYR B N 1 ATOM 2411 C CA . TYR B 2 101 ? -38.296 -39.893 4.125 1.00 27.42 ? 101 TYR B CA 1 ATOM 2412 C C . TYR B 2 101 ? -36.880 -40.465 3.933 1.00 27.06 ? 101 TYR B C 1 ATOM 2413 O O . TYR B 2 101 ? -36.585 -41.554 4.434 1.00 31.38 ? 101 TYR B O 1 ATOM 2414 C CB . TYR B 2 101 ? -39.277 -40.580 3.168 1.00 25.02 ? 101 TYR B CB 1 ATOM 2415 C CG . TYR B 2 101 ? -38.849 -40.570 1.714 1.00 27.83 ? 101 TYR B CG 1 ATOM 2416 C CD1 . TYR B 2 101 ? -38.082 -41.598 1.186 1.00 22.90 ? 101 TYR B CD1 1 ATOM 2417 C CD2 . TYR B 2 101 ? -39.221 -39.533 0.870 1.00 25.20 ? 101 TYR B CD2 1 ATOM 2418 C CE1 . TYR B 2 101 ? -37.692 -41.594 -0.152 1.00 26.45 ? 101 TYR B CE1 1 ATOM 2419 C CE2 . TYR B 2 101 ? -38.839 -39.517 -0.464 1.00 28.27 ? 101 TYR B CE2 1 ATOM 2420 C CZ . TYR B 2 101 ? -38.072 -40.549 -0.975 1.00 30.50 ? 101 TYR B CZ 1 ATOM 2421 O OH . TYR B 2 101 ? -37.692 -40.529 -2.308 1.00 23.99 ? 101 TYR B OH 1 ATOM 2422 N N . TYR B 2 102 ? -36.015 -39.749 3.216 1.00 24.84 ? 102 TYR B N 1 ATOM 2423 C CA . TYR B 2 102 ? -34.701 -40.306 2.847 1.00 22.76 ? 102 TYR B CA 1 ATOM 2424 C C . TYR B 2 102 ? -33.539 -39.675 3.617 1.00 23.16 ? 102 TYR B C 1 ATOM 2425 O O . TYR B 2 102 ? -32.387 -40.090 3.467 1.00 24.25 ? 102 TYR B O 1 ATOM 2426 C CB . TYR B 2 102 ? -34.438 -40.082 1.345 1.00 23.85 ? 102 TYR B CB 1 ATOM 2427 C CG . TYR B 2 102 ? -34.531 -38.621 0.960 1.00 24.27 ? 102 TYR B CG 1 ATOM 2428 C CD1 . TYR B 2 102 ? -33.443 -37.768 1.108 1.00 22.13 ? 102 TYR B CD1 1 ATOM 2429 C CD2 . TYR B 2 102 ? -35.726 -38.087 0.514 1.00 22.70 ? 102 TYR B CD2 1 ATOM 2430 C CE1 . TYR B 2 102 ? -33.533 -36.434 0.796 1.00 25.65 ? 102 TYR B CE1 1 ATOM 2431 C CE2 . TYR B 2 102 ? -35.832 -36.755 0.192 1.00 28.44 ? 102 TYR B CE2 1 ATOM 2432 C CZ . TYR B 2 102 ? -34.731 -35.927 0.333 1.00 32.69 ? 102 TYR B CZ 1 ATOM 2433 O OH . TYR B 2 102 ? -34.846 -34.593 0.014 1.00 26.02 ? 102 TYR B OH 1 ATOM 2434 N N . ASP B 2 103 ? -33.839 -38.660 4.420 1.00 23.13 ? 103 ASP B N 1 ATOM 2435 C CA . ASP B 2 103 ? -32.814 -37.754 4.931 1.00 17.60 ? 103 ASP B CA 1 ATOM 2436 C C . ASP B 2 103 ? -32.393 -38.057 6.385 1.00 28.93 ? 103 ASP B C 1 ATOM 2437 O O . ASP B 2 103 ? -32.860 -39.017 6.999 1.00 22.81 ? 103 ASP B O 1 ATOM 2438 C CB . ASP B 2 103 ? -33.318 -36.316 4.802 1.00 22.76 ? 103 ASP B CB 1 ATOM 2439 C CG . ASP B 2 103 ? -32.230 -35.347 4.403 1.00 24.97 ? 103 ASP B CG 1 ATOM 2440 O OD1 . ASP B 2 103 ? -31.056 -35.617 4.717 1.00 24.38 ? 103 ASP B OD1 1 ATOM 2441 O OD2 . ASP B 2 103 ? -32.552 -34.311 3.780 1.00 23.79 ? 103 ASP B OD2 1 ATOM 2442 N N . TYR B 2 104 ? -31.516 -37.226 6.936 1.00 25.30 ? 104 TYR B N 1 ATOM 2443 C CA . TYR B 2 104 ? -30.873 -37.542 8.200 1.00 19.74 ? 104 TYR B CA 1 ATOM 2444 C C . TYR B 2 104 ? -30.922 -36.381 9.183 1.00 19.58 ? 104 TYR B C 1 ATOM 2445 O O . TYR B 2 104 ? -30.318 -36.448 10.247 1.00 24.38 ? 104 TYR B O 1 ATOM 2446 C CB . TYR B 2 104 ? -29.412 -37.965 7.965 1.00 19.62 ? 104 TYR B CB 1 ATOM 2447 C CG . TYR B 2 104 ? -29.242 -39.324 7.302 1.00 22.82 ? 104 TYR B CG 1 ATOM 2448 C CD1 . TYR B 2 104 ? -28.963 -40.460 8.049 1.00 19.69 ? 104 TYR B CD1 1 ATOM 2449 C CD2 . TYR B 2 104 ? -29.357 -39.465 5.923 1.00 27.10 ? 104 TYR B CD2 1 ATOM 2450 C CE1 . TYR B 2 104 ? -28.805 -41.691 7.446 1.00 24.12 ? 104 TYR B CE1 1 ATOM 2451 C CE2 . TYR B 2 104 ? -29.202 -40.687 5.308 1.00 24.58 ? 104 TYR B CE2 1 ATOM 2452 C CZ . TYR B 2 104 ? -28.924 -41.798 6.064 1.00 28.75 ? 104 TYR B CZ 1 ATOM 2453 O OH . TYR B 2 104 ? -28.769 -43.012 5.429 1.00 22.60 ? 104 TYR B OH 1 ATOM 2454 N N . GLU B 2 105 ? -31.616 -35.308 8.836 1.00 19.00 ? 105 GLU B N 1 ATOM 2455 C CA . GLU B 2 105 ? -31.786 -34.237 9.795 1.00 19.30 ? 105 GLU B CA 1 ATOM 2456 C C . GLU B 2 105 ? -32.930 -34.617 10.744 1.00 29.89 ? 105 GLU B C 1 ATOM 2457 O O . GLU B 2 105 ? -34.094 -34.705 10.349 1.00 26.15 ? 105 GLU B O 1 ATOM 2458 C CB . GLU B 2 105 ? -31.977 -32.870 9.119 1.00 23.47 ? 105 GLU B CB 1 ATOM 2459 C CG . GLU B 2 105 ? -33.353 -32.566 8.542 1.00 25.66 ? 105 GLU B CG 1 ATOM 2460 C CD . GLU B 2 105 ? -33.584 -33.216 7.197 1.00 30.71 ? 105 GLU B CD 1 ATOM 2461 O OE1 . GLU B 2 105 ? -33.565 -32.487 6.185 1.00 36.41 ? 105 GLU B OE1 1 ATOM 2462 O OE2 . GLU B 2 105 ? -33.799 -34.449 7.149 1.00 32.03 ? 105 GLU B OE2 1 ATOM 2463 N N . PHE B 2 106 ? -32.580 -34.879 12.001 1.00 24.07 ? 106 PHE B N 1 ATOM 2464 C CA . PHE B 2 106 ? -33.527 -35.471 12.934 1.00 23.11 ? 106 PHE B CA 1 ATOM 2465 C C . PHE B 2 106 ? -34.375 -34.467 13.699 1.00 22.09 ? 106 PHE B C 1 ATOM 2466 O O . PHE B 2 106 ? -33.936 -33.879 14.686 1.00 20.25 ? 106 PHE B O 1 ATOM 2467 C CB . PHE B 2 106 ? -32.795 -36.392 13.884 1.00 22.67 ? 106 PHE B CB 1 ATOM 2468 C CG . PHE B 2 106 ? -31.910 -37.387 13.185 1.00 21.00 ? 106 PHE B CG 1 ATOM 2469 C CD1 . PHE B 2 106 ? -32.452 -38.316 12.320 1.00 18.07 ? 106 PHE B CD1 1 ATOM 2470 C CD2 . PHE B 2 106 ? -30.538 -37.396 13.407 1.00 23.33 ? 106 PHE B CD2 1 ATOM 2471 C CE1 . PHE B 2 106 ? -31.653 -39.235 11.681 1.00 21.71 ? 106 PHE B CE1 1 ATOM 2472 C CE2 . PHE B 2 106 ? -29.730 -38.310 12.778 1.00 24.09 ? 106 PHE B CE2 1 ATOM 2473 C CZ . PHE B 2 106 ? -30.287 -39.235 11.903 1.00 26.28 ? 106 PHE B CZ 1 ATOM 2474 N N . ALA B 2 107 ? -35.601 -34.283 13.225 1.00 19.96 ? 107 ALA B N 1 ATOM 2475 C CA . ALA B 2 107 ? -36.501 -33.299 13.803 1.00 21.23 ? 107 ALA B CA 1 ATOM 2476 C C . ALA B 2 107 ? -37.410 -33.889 14.884 1.00 24.57 ? 107 ALA B C 1 ATOM 2477 O O . ALA B 2 107 ? -38.071 -33.161 15.611 1.00 23.35 ? 107 ALA B O 1 ATOM 2478 C CB . ALA B 2 107 ? -37.328 -32.646 12.714 1.00 22.99 ? 107 ALA B CB 1 ATOM 2479 N N . TYR B 2 108 ? -37.448 -35.209 14.985 1.00 26.13 ? 108 TYR B N 1 ATOM 2480 C CA . TYR B 2 108 ? -38.323 -35.854 15.952 1.00 22.40 ? 108 TYR B CA 1 ATOM 2481 C C . TYR B 2 108 ? -37.562 -36.934 16.697 1.00 22.64 ? 108 TYR B C 1 ATOM 2482 O O . TYR B 2 108 ? -36.989 -37.833 16.085 1.00 25.72 ? 108 TYR B O 1 ATOM 2483 C CB . TYR B 2 108 ? -39.573 -36.422 15.271 1.00 20.23 ? 108 TYR B CB 1 ATOM 2484 C CG . TYR B 2 108 ? -40.287 -35.385 14.439 1.00 26.79 ? 108 TYR B CG 1 ATOM 2485 C CD1 . TYR B 2 108 ? -40.156 -35.368 13.048 1.00 22.43 ? 108 TYR B CD1 1 ATOM 2486 C CD2 . TYR B 2 108 ? -41.063 -34.396 15.042 1.00 21.62 ? 108 TYR B CD2 1 ATOM 2487 C CE1 . TYR B 2 108 ? -40.782 -34.410 12.285 1.00 21.21 ? 108 TYR B CE1 1 ATOM 2488 C CE2 . TYR B 2 108 ? -41.702 -33.428 14.284 1.00 27.34 ? 108 TYR B CE2 1 ATOM 2489 C CZ . TYR B 2 108 ? -41.551 -33.441 12.897 1.00 31.89 ? 108 TYR B CZ 1 ATOM 2490 O OH . TYR B 2 108 ? -42.163 -32.489 12.121 1.00 28.08 ? 108 TYR B OH 1 ATOM 2491 N N . TRP B 2 109 ? -37.558 -36.835 18.023 1.00 22.12 ? 109 TRP B N 1 ATOM 2492 C CA . TRP B 2 109 ? -36.821 -37.766 18.869 1.00 18.11 ? 109 TRP B CA 1 ATOM 2493 C C . TRP B 2 109 ? -37.708 -38.460 19.883 1.00 17.05 ? 109 TRP B C 1 ATOM 2494 O O . TRP B 2 109 ? -38.639 -37.863 20.432 1.00 19.17 ? 109 TRP B O 1 ATOM 2495 C CB . TRP B 2 109 ? -35.736 -37.020 19.620 1.00 16.67 ? 109 TRP B CB 1 ATOM 2496 C CG . TRP B 2 109 ? -34.662 -36.481 18.761 1.00 20.86 ? 109 TRP B CG 1 ATOM 2497 C CD1 . TRP B 2 109 ? -34.737 -35.399 17.945 1.00 18.54 ? 109 TRP B CD1 1 ATOM 2498 C CD2 . TRP B 2 109 ? -33.326 -36.988 18.643 1.00 23.13 ? 109 TRP B CD2 1 ATOM 2499 N NE1 . TRP B 2 109 ? -33.529 -35.192 17.324 1.00 20.72 ? 109 TRP B NE1 1 ATOM 2500 C CE2 . TRP B 2 109 ? -32.648 -36.158 17.731 1.00 24.28 ? 109 TRP B CE2 1 ATOM 2501 C CE3 . TRP B 2 109 ? -32.638 -38.064 19.220 1.00 17.46 ? 109 TRP B CE3 1 ATOM 2502 C CZ2 . TRP B 2 109 ? -31.314 -36.368 17.379 1.00 24.09 ? 109 TRP B CZ2 1 ATOM 2503 C CZ3 . TRP B 2 109 ? -31.308 -38.269 18.875 1.00 14.89 ? 109 TRP B CZ3 1 ATOM 2504 C CH2 . TRP B 2 109 ? -30.664 -37.427 17.965 1.00 23.53 ? 109 TRP B CH2 1 ATOM 2505 N N . GLY B 2 110 ? -37.417 -39.730 20.136 1.00 18.24 ? 110 GLY B N 1 ATOM 2506 C CA . GLY B 2 110 ? -37.977 -40.392 21.302 1.00 20.46 ? 110 GLY B CA 1 ATOM 2507 C C . GLY B 2 110 ? -37.466 -39.698 22.562 1.00 24.21 ? 110 GLY B C 1 ATOM 2508 O O . GLY B 2 110 ? -36.534 -38.874 22.512 1.00 18.33 ? 110 GLY B O 1 ATOM 2509 N N . GLN B 2 111 ? -38.064 -40.023 23.701 1.00 20.10 ? 111 GLN B N 1 ATOM 2510 C CA . GLN B 2 111 ? -37.663 -39.381 24.949 1.00 23.71 ? 111 GLN B CA 1 ATOM 2511 C C . GLN B 2 111 ? -36.334 -39.950 25.460 1.00 19.35 ? 111 GLN B C 1 ATOM 2512 O O . GLN B 2 111 ? -35.732 -39.410 26.383 1.00 19.94 ? 111 GLN B O 1 ATOM 2513 C CB . GLN B 2 111 ? -38.786 -39.459 26.005 1.00 14.16 ? 111 GLN B CB 1 ATOM 2514 C CG . GLN B 2 111 ? -38.874 -40.758 26.785 1.00 12.52 ? 111 GLN B CG 1 ATOM 2515 C CD . GLN B 2 111 ? -39.548 -41.887 26.025 1.00 22.79 ? 111 GLN B CD 1 ATOM 2516 O OE1 . GLN B 2 111 ? -39.666 -41.867 24.790 1.00 21.36 ? 111 GLN B OE1 1 ATOM 2517 N NE2 . GLN B 2 111 ? -39.998 -42.887 26.766 1.00 17.73 ? 111 GLN B NE2 1 ATOM 2518 N N . GLY B 2 112 ? -35.867 -41.021 24.822 1.00 21.55 ? 112 GLY B N 1 ATOM 2519 C CA . GLY B 2 112 ? -34.619 -41.671 25.192 1.00 19.49 ? 112 GLY B CA 1 ATOM 2520 C C . GLY B 2 112 ? -34.848 -42.787 26.198 1.00 23.91 ? 112 GLY B C 1 ATOM 2521 O O . GLY B 2 112 ? -35.839 -42.771 26.931 1.00 24.27 ? 112 GLY B O 1 ATOM 2522 N N . THR B 2 113 ? -33.936 -43.756 26.225 1.00 20.83 ? 113 THR B N 1 ATOM 2523 C CA . THR B 2 113 ? -34.019 -44.891 27.136 1.00 12.57 ? 113 THR B CA 1 ATOM 2524 C C . THR B 2 113 ? -32.649 -45.127 27.761 1.00 21.26 ? 113 THR B C 1 ATOM 2525 O O . THR B 2 113 ? -31.741 -45.662 27.106 1.00 23.40 ? 113 THR B O 1 ATOM 2526 C CB . THR B 2 113 ? -34.453 -46.186 26.404 1.00 19.65 ? 113 THR B CB 1 ATOM 2527 O OG1 . THR B 2 113 ? -35.724 -45.997 25.761 1.00 19.94 ? 113 THR B OG1 1 ATOM 2528 C CG2 . THR B 2 113 ? -34.539 -47.350 27.386 1.00 18.96 ? 113 THR B CG2 1 ATOM 2529 N N . LEU B 2 114 ? -32.488 -44.719 29.018 1.00 20.86 ? 114 LEU B N 1 ATOM 2530 C CA . LEU B 2 114 ? -31.210 -44.886 29.709 1.00 15.45 ? 114 LEU B CA 1 ATOM 2531 C C . LEU B 2 114 ? -30.961 -46.355 30.031 1.00 17.21 ? 114 LEU B C 1 ATOM 2532 O O . LEU B 2 114 ? -31.660 -46.965 30.845 1.00 21.38 ? 114 LEU B O 1 ATOM 2533 C CB . LEU B 2 114 ? -31.141 -44.040 30.987 1.00 15.68 ? 114 LEU B CB 1 ATOM 2534 C CG . LEU B 2 114 ? -29.893 -44.245 31.857 1.00 18.80 ? 114 LEU B CG 1 ATOM 2535 C CD1 . LEU B 2 114 ? -28.614 -44.057 31.051 1.00 15.95 ? 114 LEU B CD1 1 ATOM 2536 C CD2 . LEU B 2 114 ? -29.886 -43.300 33.060 1.00 20.67 ? 114 LEU B CD2 1 ATOM 2537 N N . VAL B 2 115 ? -29.956 -46.920 29.387 1.00 18.05 ? 115 VAL B N 1 ATOM 2538 C CA . VAL B 2 115 ? -29.623 -48.301 29.617 1.00 18.18 ? 115 VAL B CA 1 ATOM 2539 C C . VAL B 2 115 ? -28.318 -48.363 30.369 1.00 23.31 ? 115 VAL B C 1 ATOM 2540 O O . VAL B 2 115 ? -27.344 -47.710 29.983 1.00 24.82 ? 115 VAL B O 1 ATOM 2541 C CB . VAL B 2 115 ? -29.492 -49.067 28.303 1.00 18.99 ? 115 VAL B CB 1 ATOM 2542 C CG1 . VAL B 2 115 ? -29.033 -50.491 28.570 1.00 26.42 ? 115 VAL B CG1 1 ATOM 2543 C CG2 . VAL B 2 115 ? -30.818 -49.055 27.563 1.00 16.42 ? 115 VAL B CG2 1 ATOM 2544 N N . THR B 2 116 ? -28.310 -49.137 31.454 1.00 22.52 ? 116 THR B N 1 ATOM 2545 C CA . THR B 2 116 ? -27.113 -49.333 32.257 1.00 19.01 ? 116 THR B CA 1 ATOM 2546 C C . THR B 2 116 ? -26.624 -50.778 32.114 1.00 26.02 ? 116 THR B C 1 ATOM 2547 O O . THR B 2 116 ? -27.376 -51.732 32.334 1.00 24.89 ? 116 THR B O 1 ATOM 2548 C CB . THR B 2 116 ? -27.373 -48.984 33.756 1.00 26.26 ? 116 THR B CB 1 ATOM 2549 O OG1 . THR B 2 116 ? -27.857 -47.637 33.874 1.00 22.60 ? 116 THR B OG1 1 ATOM 2550 C CG2 . THR B 2 116 ? -26.094 -49.135 34.589 1.00 20.37 ? 116 THR B CG2 1 ATOM 2551 N N . VAL B 2 117 ? -25.371 -50.947 31.714 1.00 24.64 ? 117 VAL B N 1 ATOM 2552 C CA . VAL B 2 117 ? -24.796 -52.282 31.664 1.00 22.56 ? 117 VAL B CA 1 ATOM 2553 C C . VAL B 2 117 ? -24.024 -52.509 32.947 1.00 23.82 ? 117 VAL B C 1 ATOM 2554 O O . VAL B 2 117 ? -23.024 -51.855 33.208 1.00 25.55 ? 117 VAL B O 1 ATOM 2555 C CB . VAL B 2 117 ? -23.878 -52.467 30.460 1.00 32.14 ? 117 VAL B CB 1 ATOM 2556 C CG1 . VAL B 2 117 ? -23.378 -53.912 30.395 1.00 27.77 ? 117 VAL B CG1 1 ATOM 2557 C CG2 . VAL B 2 117 ? -24.624 -52.085 29.183 1.00 28.21 ? 117 VAL B CG2 1 ATOM 2558 N N . SER B 2 118 ? -24.521 -53.413 33.775 1.00 31.57 ? 118 SER B N 1 ATOM 2559 C CA . SER B 2 118 ? -23.919 -53.645 35.076 1.00 26.85 ? 118 SER B CA 1 ATOM 2560 C C . SER B 2 118 ? -24.266 -55.032 35.551 1.00 33.14 ? 118 SER B C 1 ATOM 2561 O O . SER B 2 118 ? -25.335 -55.559 35.238 1.00 38.97 ? 118 SER B O 1 ATOM 2562 C CB . SER B 2 118 ? -24.405 -52.617 36.099 1.00 26.49 ? 118 SER B CB 1 ATOM 2563 O OG . SER B 2 118 ? -23.996 -52.978 37.408 1.00 32.43 ? 118 SER B OG 1 ATOM 2564 N N . ALA B 2 119 ? -23.359 -55.626 36.310 1.00 38.77 ? 119 ALA B N 1 ATOM 2565 C CA . ALA B 2 119 ? -23.601 -56.951 36.850 1.00 39.41 ? 119 ALA B CA 1 ATOM 2566 C C . ALA B 2 119 ? -24.549 -56.922 38.057 1.00 42.90 ? 119 ALA B C 1 ATOM 2567 O O . ALA B 2 119 ? -25.055 -57.963 38.474 1.00 46.01 ? 119 ALA B O 1 ATOM 2568 C CB . ALA B 2 119 ? -22.296 -57.620 37.200 1.00 43.20 ? 119 ALA B CB 1 ATOM 2569 N N . ALA B 2 120 ? -24.806 -55.736 38.608 1.00 35.38 ? 120 ALA B N 1 ATOM 2570 C CA . ALA B 2 120 ? -25.632 -55.643 39.819 1.00 33.12 ? 120 ALA B CA 1 ATOM 2571 C C . ALA B 2 120 ? -27.098 -56.003 39.601 1.00 31.98 ? 120 ALA B C 1 ATOM 2572 O O . ALA B 2 120 ? -27.485 -56.513 38.553 1.00 35.96 ? 120 ALA B O 1 ATOM 2573 C CB . ALA B 2 120 ? -25.517 -54.270 40.466 1.00 27.07 ? 120 ALA B CB 1 ATOM 2574 N N . SER B 2 121 ? -27.919 -55.735 40.604 1.00 29.11 ? 121 SER B N 1 ATOM 2575 C CA . SER B 2 121 ? -29.337 -56.023 40.472 1.00 29.11 ? 121 SER B CA 1 ATOM 2576 C C . SER B 2 121 ? -30.160 -54.780 40.744 1.00 29.68 ? 121 SER B C 1 ATOM 2577 O O . SER B 2 121 ? -29.678 -53.823 41.343 1.00 27.52 ? 121 SER B O 1 ATOM 2578 C CB . SER B 2 121 ? -29.765 -57.170 41.383 1.00 29.16 ? 121 SER B CB 1 ATOM 2579 O OG . SER B 2 121 ? -29.346 -56.928 42.699 1.00 30.39 ? 121 SER B OG 1 ATOM 2580 N N . THR B 2 122 ? -31.400 -54.803 40.273 1.00 26.60 ? 122 THR B N 1 ATOM 2581 C CA . THR B 2 122 ? -32.283 -53.659 40.377 1.00 25.12 ? 122 THR B CA 1 ATOM 2582 C C . THR B 2 122 ? -32.813 -53.552 41.793 1.00 27.17 ? 122 THR B C 1 ATOM 2583 O O . THR B 2 122 ? -33.141 -54.554 42.428 1.00 33.03 ? 122 THR B O 1 ATOM 2584 C CB . THR B 2 122 ? -33.450 -53.768 39.382 1.00 26.04 ? 122 THR B CB 1 ATOM 2585 O OG1 . THR B 2 122 ? -32.931 -54.071 38.081 1.00 27.18 ? 122 THR B OG1 1 ATOM 2586 C CG2 . THR B 2 122 ? -34.197 -52.469 39.305 1.00 26.19 ? 122 THR B CG2 1 ATOM 2587 N N . LYS B 2 123 ? -32.876 -52.328 42.293 1.00 29.01 ? 123 LYS B N 1 ATOM 2588 C CA . LYS B 2 123 ? -33.334 -52.090 43.644 1.00 22.30 ? 123 LYS B CA 1 ATOM 2589 C C . LYS B 2 123 ? -34.099 -50.778 43.703 1.00 16.51 ? 123 LYS B C 1 ATOM 2590 O O . LYS B 2 123 ? -33.583 -49.739 43.307 1.00 20.57 ? 123 LYS B O 1 ATOM 2591 C CB . LYS B 2 123 ? -32.140 -52.058 44.596 1.00 23.99 ? 123 LYS B CB 1 ATOM 2592 C CG . LYS B 2 123 ? -32.555 -51.928 46.052 1.00 26.58 ? 123 LYS B CG 1 ATOM 2593 C CD . LYS B 2 123 ? -31.372 -51.773 46.981 1.00 22.73 ? 123 LYS B CD 1 ATOM 2594 C CE . LYS B 2 123 ? -31.872 -51.492 48.390 1.00 24.08 ? 123 LYS B CE 1 ATOM 2595 N NZ . LYS B 2 123 ? -32.866 -50.374 48.398 1.00 24.61 ? 123 LYS B NZ 1 ATOM 2596 N N . GLY B 2 124 ? -35.334 -50.831 44.184 1.00 16.98 ? 124 GLY B N 1 ATOM 2597 C CA . GLY B 2 124 ? -36.147 -49.635 44.309 1.00 16.77 ? 124 GLY B CA 1 ATOM 2598 C C . GLY B 2 124 ? -35.679 -48.725 45.435 1.00 18.03 ? 124 GLY B C 1 ATOM 2599 O O . GLY B 2 124 ? -35.011 -49.173 46.368 1.00 20.51 ? 124 GLY B O 1 ATOM 2600 N N . PRO B 2 125 ? -36.030 -47.434 45.360 1.00 13.95 ? 125 PRO B N 1 ATOM 2601 C CA . PRO B 2 125 ? -35.624 -46.481 46.396 1.00 15.60 ? 125 PRO B CA 1 ATOM 2602 C C . PRO B 2 125 ? -36.562 -46.520 47.593 1.00 17.42 ? 125 PRO B C 1 ATOM 2603 O O . PRO B 2 125 ? -37.723 -46.877 47.424 1.00 13.88 ? 125 PRO B O 1 ATOM 2604 C CB . PRO B 2 125 ? -35.796 -45.136 45.699 1.00 13.87 ? 125 PRO B CB 1 ATOM 2605 C CG . PRO B 2 125 ? -36.985 -45.363 44.794 1.00 12.59 ? 125 PRO B CG 1 ATOM 2606 C CD . PRO B 2 125 ? -36.883 -46.808 44.336 1.00 13.90 ? 125 PRO B CD 1 ATOM 2607 N N . SER B 2 126 ? -36.048 -46.192 48.778 1.00 18.20 ? 126 SER B N 1 ATOM 2608 C CA . SER B 2 126 ? -36.872 -45.803 49.912 1.00 11.55 ? 126 SER B CA 1 ATOM 2609 C C . SER B 2 126 ? -37.047 -44.299 49.806 1.00 15.95 ? 126 SER B C 1 ATOM 2610 O O . SER B 2 126 ? -36.121 -43.593 49.413 1.00 16.27 ? 126 SER B O 1 ATOM 2611 C CB . SER B 2 126 ? -36.174 -46.125 51.231 1.00 19.67 ? 126 SER B CB 1 ATOM 2612 O OG . SER B 2 126 ? -35.937 -47.515 51.379 1.00 26.03 ? 126 SER B OG 1 ATOM 2613 N N . VAL B 2 127 ? -38.221 -43.799 50.165 1.00 14.78 ? 127 VAL B N 1 ATOM 2614 C CA . VAL B 2 127 ? -38.506 -42.382 50.023 1.00 11.93 ? 127 VAL B CA 1 ATOM 2615 C C . VAL B 2 127 ? -38.789 -41.774 51.388 1.00 15.61 ? 127 VAL B C 1 ATOM 2616 O O . VAL B 2 127 ? -39.701 -42.195 52.074 1.00 13.77 ? 127 VAL B O 1 ATOM 2617 C CB . VAL B 2 127 ? -39.697 -42.165 49.089 1.00 15.84 ? 127 VAL B CB 1 ATOM 2618 C CG1 . VAL B 2 127 ? -39.898 -40.688 48.814 1.00 10.69 ? 127 VAL B CG1 1 ATOM 2619 C CG2 . VAL B 2 127 ? -39.482 -42.947 47.778 1.00 18.13 ? 127 VAL B CG2 1 ATOM 2620 N N . PHE B 2 128 ? -37.991 -40.779 51.777 1.00 19.72 ? 128 PHE B N 1 ATOM 2621 C CA . PHE B 2 128 ? -38.120 -40.158 53.093 1.00 20.92 ? 128 PHE B CA 1 ATOM 2622 C C . PHE B 2 128 ? -38.491 -38.677 53.014 1.00 17.82 ? 128 PHE B C 1 ATOM 2623 O O . PHE B 2 128 ? -38.076 -37.983 52.094 1.00 18.41 ? 128 PHE B O 1 ATOM 2624 C CB . PHE B 2 128 ? -36.840 -40.368 53.903 1.00 17.88 ? 128 PHE B CB 1 ATOM 2625 C CG . PHE B 2 128 ? -36.502 -41.812 54.116 1.00 18.65 ? 128 PHE B CG 1 ATOM 2626 C CD1 . PHE B 2 128 ? -37.311 -42.612 54.904 1.00 15.88 ? 128 PHE B CD1 1 ATOM 2627 C CD2 . PHE B 2 128 ? -35.379 -42.374 53.523 1.00 19.60 ? 128 PHE B CD2 1 ATOM 2628 C CE1 . PHE B 2 128 ? -37.009 -43.948 55.104 1.00 17.59 ? 128 PHE B CE1 1 ATOM 2629 C CE2 . PHE B 2 128 ? -35.070 -43.716 53.720 1.00 15.80 ? 128 PHE B CE2 1 ATOM 2630 C CZ . PHE B 2 128 ? -35.892 -44.500 54.503 1.00 21.69 ? 128 PHE B CZ 1 ATOM 2631 N N . PRO B 2 129 ? -39.294 -38.190 53.972 1.00 15.27 ? 129 PRO B N 1 ATOM 2632 C CA . PRO B 2 129 ? -39.680 -36.779 53.908 1.00 14.41 ? 129 PRO B CA 1 ATOM 2633 C C . PRO B 2 129 ? -38.547 -35.856 54.349 1.00 14.30 ? 129 PRO B C 1 ATOM 2634 O O . PRO B 2 129 ? -37.750 -36.207 55.216 1.00 14.49 ? 129 PRO B O 1 ATOM 2635 C CB . PRO B 2 129 ? -40.844 -36.694 54.899 1.00 9.66 ? 129 PRO B CB 1 ATOM 2636 C CG . PRO B 2 129 ? -40.504 -37.714 55.923 1.00 17.16 ? 129 PRO B CG 1 ATOM 2637 C CD . PRO B 2 129 ? -39.868 -38.860 55.151 1.00 17.98 ? 129 PRO B CD 1 ATOM 2638 N N . LEU B 2 130 ? -38.464 -34.690 53.724 1.00 15.82 ? 130 LEU B N 1 ATOM 2639 C CA . LEU B 2 130 ? -37.575 -33.635 54.189 1.00 17.48 ? 130 LEU B CA 1 ATOM 2640 C C . LEU B 2 130 ? -38.507 -32.544 54.647 1.00 12.01 ? 130 LEU B C 1 ATOM 2641 O O . LEU B 2 130 ? -39.007 -31.758 53.843 1.00 17.56 ? 130 LEU B O 1 ATOM 2642 C CB . LEU B 2 130 ? -36.646 -33.155 53.071 1.00 17.99 ? 130 LEU B CB 1 ATOM 2643 C CG . LEU B 2 130 ? -35.607 -34.179 52.642 1.00 15.64 ? 130 LEU B CG 1 ATOM 2644 C CD1 . LEU B 2 130 ? -34.785 -33.646 51.503 1.00 17.14 ? 130 LEU B CD1 1 ATOM 2645 C CD2 . LEU B 2 130 ? -34.723 -34.517 53.824 1.00 13.14 ? 130 LEU B CD2 1 ATOM 2646 N N . ALA B 2 131 ? -38.781 -32.545 55.945 1.00 13.07 ? 131 ALA B N 1 ATOM 2647 C CA . ALA B 2 131 ? -39.909 -31.801 56.494 1.00 20.59 ? 131 ALA B CA 1 ATOM 2648 C C . ALA B 2 131 ? -39.574 -30.339 56.683 1.00 21.83 ? 131 ALA B C 1 ATOM 2649 O O . ALA B 2 131 ? -38.516 -30.005 57.214 1.00 25.27 ? 131 ALA B O 1 ATOM 2650 C CB . ALA B 2 131 ? -40.355 -32.403 57.803 1.00 12.31 ? 131 ALA B CB 1 ATOM 2651 N N . PRO B 2 132 ? -40.498 -29.459 56.281 1.00 24.36 ? 132 PRO B N 1 ATOM 2652 C CA . PRO B 2 132 ? -40.363 -28.030 56.576 1.00 26.46 ? 132 PRO B CA 1 ATOM 2653 C C . PRO B 2 132 ? -40.483 -27.798 58.072 1.00 24.63 ? 132 PRO B C 1 ATOM 2654 O O . PRO B 2 132 ? -41.174 -28.552 58.743 1.00 32.05 ? 132 PRO B O 1 ATOM 2655 C CB . PRO B 2 132 ? -41.581 -27.420 55.884 1.00 22.21 ? 132 PRO B CB 1 ATOM 2656 C CG . PRO B 2 132 ? -42.617 -28.505 55.951 1.00 25.19 ? 132 PRO B CG 1 ATOM 2657 C CD . PRO B 2 132 ? -41.840 -29.798 55.775 1.00 27.88 ? 132 PRO B CD 1 ATOM 2658 N N . SER B 2 133 ? -39.817 -26.774 58.585 1.00 41.20 ? 133 SER B N 1 ATOM 2659 C CA . SER B 2 133 ? -40.000 -26.343 59.969 1.00 48.26 ? 133 SER B CA 1 ATOM 2660 C C . SER B 2 133 ? -39.585 -24.890 60.041 1.00 51.10 ? 133 SER B C 1 ATOM 2661 O O . SER B 2 133 ? -39.588 -24.203 59.027 1.00 46.27 ? 133 SER B O 1 ATOM 2662 C CB . SER B 2 133 ? -39.136 -27.162 60.921 1.00 49.29 ? 133 SER B CB 1 ATOM 2663 O OG . SER B 2 133 ? -37.798 -26.704 60.900 1.00 56.04 ? 133 SER B OG 1 ATOM 2664 N N . SER B 2 134 ? -39.204 -24.431 61.230 1.00 58.75 ? 134 SER B N 1 ATOM 2665 C CA . SER B 2 134 ? -38.603 -23.106 61.383 1.00 61.36 ? 134 SER B CA 1 ATOM 2666 C C . SER B 2 134 ? -37.157 -23.096 60.862 1.00 64.18 ? 134 SER B C 1 ATOM 2667 O O . SER B 2 134 ? -36.680 -22.083 60.346 1.00 56.74 ? 134 SER B O 1 ATOM 2668 C CB . SER B 2 134 ? -38.648 -22.667 62.842 1.00 49.04 ? 134 SER B CB 1 ATOM 2669 O OG . SER B 2 134 ? -38.058 -23.645 63.678 1.00 60.49 ? 134 SER B OG 1 ATOM 2670 N N . LYS B 2 135 ? -36.476 -24.237 60.991 1.00 67.13 ? 135 LYS B N 1 ATOM 2671 C CA . LYS B 2 135 ? -35.095 -24.408 60.516 1.00 65.40 ? 135 LYS B CA 1 ATOM 2672 C C . LYS B 2 135 ? -35.033 -24.389 58.985 1.00 68.00 ? 135 LYS B C 1 ATOM 2673 O O . LYS B 2 135 ? -33.945 -24.331 58.374 1.00 50.17 ? 135 LYS B O 1 ATOM 2674 C CB . LYS B 2 135 ? -34.499 -25.722 61.044 1.00 57.22 ? 135 LYS B CB 1 ATOM 2675 C CG . LYS B 2 135 ? -34.368 -25.783 62.559 1.00 55.12 ? 135 LYS B CG 1 ATOM 2676 C CD . LYS B 2 135 ? -33.471 -24.668 63.059 1.00 53.09 ? 135 LYS B CD 1 ATOM 2677 C CE . LYS B 2 135 ? -33.346 -24.699 64.572 1.00 46.87 ? 135 LYS B CE 1 ATOM 2678 N NZ . LYS B 2 135 ? -32.359 -23.686 65.049 1.00 39.26 ? 135 LYS B NZ 1 ATOM 2679 N N . SER B 2 136 ? -36.214 -24.444 58.375 1.00 56.98 ? 136 SER B N 1 ATOM 2680 C CA . SER B 2 136 ? -36.322 -24.360 56.930 1.00 56.99 ? 136 SER B CA 1 ATOM 2681 C C . SER B 2 136 ? -37.440 -23.396 56.463 1.00 54.20 ? 136 SER B C 1 ATOM 2682 O O . SER B 2 136 ? -38.040 -23.607 55.401 1.00 38.91 ? 136 SER B O 1 ATOM 2683 C CB . SER B 2 136 ? -36.457 -25.765 56.316 1.00 35.31 ? 136 SER B CB 1 ATOM 2684 O OG . SER B 2 136 ? -37.776 -26.026 55.881 1.00 34.04 ? 136 SER B OG 1 ATOM 2685 N N . THR B 2 137 ? -37.700 -22.347 57.259 1.00 47.92 ? 137 THR B N 1 ATOM 2686 C CA . THR B 2 137 ? -38.654 -21.276 56.895 1.00 56.63 ? 137 THR B CA 1 ATOM 2687 C C . THR B 2 137 ? -38.101 -19.864 57.145 1.00 65.76 ? 137 THR B C 1 ATOM 2688 O O . THR B 2 137 ? -38.082 -19.386 58.291 1.00 66.73 ? 137 THR B O 1 ATOM 2689 C CB . THR B 2 137 ? -40.037 -21.386 57.628 1.00 52.85 ? 137 THR B CB 1 ATOM 2690 O OG1 . THR B 2 137 ? -40.720 -22.586 57.236 1.00 54.30 ? 137 THR B OG1 1 ATOM 2691 C CG2 . THR B 2 137 ? -40.930 -20.183 57.292 1.00 43.13 ? 137 THR B CG2 1 ATOM 2692 N N . SER B 2 138 ? -37.677 -19.192 56.073 1.00 54.37 ? 138 SER B N 1 ATOM 2693 C CA . SER B 2 138 ? -37.157 -17.832 56.193 1.00 62.64 ? 138 SER B CA 1 ATOM 2694 C C . SER B 2 138 ? -37.940 -16.829 55.332 1.00 56.46 ? 138 SER B C 1 ATOM 2695 O O . SER B 2 138 ? -38.043 -16.979 54.106 1.00 51.07 ? 138 SER B O 1 ATOM 2696 C CB . SER B 2 138 ? -35.654 -17.788 55.862 1.00 58.87 ? 138 SER B CB 1 ATOM 2697 O OG . SER B 2 138 ? -34.999 -16.709 56.530 1.00 64.57 ? 138 SER B OG 1 ATOM 2698 N N . GLY B 2 139 ? -38.492 -15.809 55.990 1.00 56.69 ? 139 GLY B N 1 ATOM 2699 C CA . GLY B 2 139 ? -39.212 -14.738 55.315 1.00 41.42 ? 139 GLY B CA 1 ATOM 2700 C C . GLY B 2 139 ? -40.497 -15.166 54.628 1.00 40.88 ? 139 GLY B C 1 ATOM 2701 O O . GLY B 2 139 ? -40.753 -14.787 53.483 1.00 46.45 ? 139 GLY B O 1 ATOM 2702 N N . GLY B 2 140 ? -41.312 -15.957 55.321 1.00 34.49 ? 140 GLY B N 1 ATOM 2703 C CA . GLY B 2 140 ? -42.550 -16.445 54.740 1.00 39.00 ? 140 GLY B CA 1 ATOM 2704 C C . GLY B 2 140 ? -42.409 -17.582 53.733 1.00 30.92 ? 140 GLY B C 1 ATOM 2705 O O . GLY B 2 140 ? -43.410 -18.113 53.271 1.00 31.21 ? 140 GLY B O 1 ATOM 2706 N N . THR B 2 141 ? -41.180 -17.959 53.396 1.00 29.02 ? 141 THR B N 1 ATOM 2707 C CA . THR B 2 141 ? -40.939 -19.042 52.447 1.00 25.61 ? 141 THR B CA 1 ATOM 2708 C C . THR B 2 141 ? -40.445 -20.307 53.151 1.00 31.53 ? 141 THR B C 1 ATOM 2709 O O . THR B 2 141 ? -39.499 -20.257 53.943 1.00 35.58 ? 141 THR B O 1 ATOM 2710 C CB . THR B 2 141 ? -39.941 -18.598 51.349 1.00 24.35 ? 141 THR B CB 1 ATOM 2711 O OG1 . THR B 2 141 ? -40.611 -17.713 50.446 1.00 23.75 ? 141 THR B OG1 1 ATOM 2712 C CG2 . THR B 2 141 ? -39.394 -19.792 50.568 1.00 17.74 ? 141 THR B CG2 1 ATOM 2713 N N . ALA B 2 142 ? -41.093 -21.436 52.881 1.00 20.05 ? 142 ALA B N 1 ATOM 2714 C CA . ALA B 2 142 ? -40.653 -22.712 53.456 1.00 23.71 ? 142 ALA B CA 1 ATOM 2715 C C . ALA B 2 142 ? -40.084 -23.661 52.395 1.00 24.02 ? 142 ALA B C 1 ATOM 2716 O O . ALA B 2 142 ? -40.524 -23.675 51.235 1.00 26.02 ? 142 ALA B O 1 ATOM 2717 C CB . ALA B 2 142 ? -41.795 -23.390 54.234 1.00 20.89 ? 142 ALA B CB 1 ATOM 2718 N N . ALA B 2 143 ? -39.111 -24.466 52.795 1.00 21.68 ? 143 ALA B N 1 ATOM 2719 C CA . ALA B 2 143 ? -38.538 -25.462 51.903 1.00 19.54 ? 143 ALA B CA 1 ATOM 2720 C C . ALA B 2 143 ? -38.880 -26.856 52.395 1.00 17.65 ? 143 ALA B C 1 ATOM 2721 O O . ALA B 2 143 ? -38.886 -27.126 53.586 1.00 20.05 ? 143 ALA B O 1 ATOM 2722 C CB . ALA B 2 143 ? -37.042 -25.283 51.778 1.00 17.63 ? 143 ALA B CB 1 ATOM 2723 N N . LEU B 2 144 ? -39.176 -27.744 51.468 1.00 17.45 ? 144 LEU B N 1 ATOM 2724 C CA . LEU B 2 144 ? -39.517 -29.097 51.834 1.00 17.84 ? 144 LEU B CA 1 ATOM 2725 C C . LEU B 2 144 ? -39.136 -30.009 50.680 1.00 19.98 ? 144 LEU B C 1 ATOM 2726 O O . LEU B 2 144 ? -39.039 -29.573 49.524 1.00 17.93 ? 144 LEU B O 1 ATOM 2727 C CB . LEU B 2 144 ? -41.003 -29.196 52.205 1.00 16.81 ? 144 LEU B CB 1 ATOM 2728 C CG . LEU B 2 144 ? -42.035 -28.955 51.112 1.00 17.10 ? 144 LEU B CG 1 ATOM 2729 C CD1 . LEU B 2 144 ? -42.309 -30.256 50.402 1.00 20.38 ? 144 LEU B CD1 1 ATOM 2730 C CD2 . LEU B 2 144 ? -43.317 -28.408 51.694 1.00 25.48 ? 144 LEU B CD2 1 ATOM 2731 N N . GLY B 2 145 ? -38.924 -31.276 50.991 1.00 15.30 ? 145 GLY B N 1 ATOM 2732 C CA . GLY B 2 145 ? -38.471 -32.187 49.972 1.00 14.13 ? 145 GLY B CA 1 ATOM 2733 C C . GLY B 2 145 ? -38.653 -33.646 50.322 1.00 16.63 ? 145 GLY B C 1 ATOM 2734 O O . GLY B 2 145 ? -39.235 -34.002 51.350 1.00 13.29 ? 145 GLY B O 1 ATOM 2735 N N . CYS B 2 146 ? -38.146 -34.482 49.426 1.00 17.05 ? 146 CYS B N 1 ATOM 2736 C CA . CYS B 2 146 ? -38.155 -35.921 49.570 1.00 16.87 ? 146 CYS B CA 1 ATOM 2737 C C . CYS B 2 146 ? -36.761 -36.435 49.341 1.00 19.65 ? 146 CYS B C 1 ATOM 2738 O O . CYS B 2 146 ? -36.095 -36.050 48.366 1.00 20.43 ? 146 CYS B O 1 ATOM 2739 C CB . CYS B 2 146 ? -39.090 -36.546 48.538 1.00 19.12 ? 146 CYS B CB 1 ATOM 2740 S SG . CYS B 2 146 ? -40.776 -36.520 49.091 1.00 34.15 ? 146 CYS B SG 1 ATOM 2741 N N . LEU B 2 147 ? -36.318 -37.306 50.235 1.00 15.33 ? 147 LEU B N 1 ATOM 2742 C CA . LEU B 2 147 ? -35.054 -38.003 50.045 1.00 17.22 ? 147 LEU B CA 1 ATOM 2743 C C . LEU B 2 147 ? -35.345 -39.341 49.374 1.00 15.73 ? 147 LEU B C 1 ATOM 2744 O O . LEU B 2 147 ? -36.110 -40.149 49.889 1.00 21.13 ? 147 LEU B O 1 ATOM 2745 C CB . LEU B 2 147 ? -34.341 -38.187 51.384 1.00 18.13 ? 147 LEU B CB 1 ATOM 2746 C CG . LEU B 2 147 ? -33.075 -39.042 51.441 1.00 20.46 ? 147 LEU B CG 1 ATOM 2747 C CD1 . LEU B 2 147 ? -31.924 -38.414 50.664 1.00 14.85 ? 147 LEU B CD1 1 ATOM 2748 C CD2 . LEU B 2 147 ? -32.680 -39.273 52.895 1.00 19.76 ? 147 LEU B CD2 1 ATOM 2749 N N . VAL B 2 148 ? -34.772 -39.538 48.194 1.00 17.36 ? 148 VAL B N 1 ATOM 2750 C CA . VAL B 2 148 ? -34.999 -40.742 47.411 1.00 11.93 ? 148 VAL B CA 1 ATOM 2751 C C . VAL B 2 148 ? -33.718 -41.558 47.422 1.00 21.25 ? 148 VAL B C 1 ATOM 2752 O O . VAL B 2 148 ? -32.765 -41.259 46.701 1.00 24.55 ? 148 VAL B O 1 ATOM 2753 C CB . VAL B 2 148 ? -35.399 -40.388 45.979 1.00 20.59 ? 148 VAL B CB 1 ATOM 2754 C CG1 . VAL B 2 148 ? -35.666 -41.652 45.166 1.00 13.61 ? 148 VAL B CG1 1 ATOM 2755 C CG2 . VAL B 2 148 ? -36.621 -39.470 46.003 1.00 13.59 ? 148 VAL B CG2 1 ATOM 2756 N N . LYS B 2 149 ? -33.700 -42.593 48.253 1.00 18.48 ? 149 LYS B N 1 ATOM 2757 C CA . LYS B 2 149 ? -32.443 -43.181 48.685 1.00 18.66 ? 149 LYS B CA 1 ATOM 2758 C C . LYS B 2 149 ? -32.268 -44.642 48.284 1.00 18.36 ? 149 LYS B C 1 ATOM 2759 O O . LYS B 2 149 ? -33.229 -45.407 48.246 1.00 20.66 ? 149 LYS B O 1 ATOM 2760 C CB . LYS B 2 149 ? -32.315 -43.011 50.205 1.00 20.56 ? 149 LYS B CB 1 ATOM 2761 C CG . LYS B 2 149 ? -30.976 -43.388 50.789 1.00 23.97 ? 149 LYS B CG 1 ATOM 2762 C CD . LYS B 2 149 ? -30.680 -42.578 52.028 1.00 23.42 ? 149 LYS B CD 1 ATOM 2763 C CE . LYS B 2 149 ? -29.693 -43.304 52.917 1.00 23.74 ? 149 LYS B CE 1 ATOM 2764 N NZ . LYS B 2 149 ? -28.731 -44.090 52.123 1.00 27.35 ? 149 LYS B NZ 1 ATOM 2765 N N . ASP B 2 150 ? -31.028 -45.001 47.959 1.00 27.67 ? 150 ASP B N 1 ATOM 2766 C CA . ASP B 2 150 ? -30.615 -46.396 47.739 1.00 22.44 ? 150 ASP B CA 1 ATOM 2767 C C . ASP B 2 150 ? -31.319 -47.145 46.613 1.00 17.48 ? 150 ASP B C 1 ATOM 2768 O O . ASP B 2 150 ? -31.897 -48.205 46.829 1.00 27.10 ? 150 ASP B O 1 ATOM 2769 C CB . ASP B 2 150 ? -30.692 -47.186 49.055 1.00 16.27 ? 150 ASP B CB 1 ATOM 2770 C CG . ASP B 2 150 ? -29.812 -46.580 50.137 1.00 26.15 ? 150 ASP B CG 1 ATOM 2771 O OD1 . ASP B 2 150 ? -28.831 -45.896 49.770 1.00 25.12 ? 150 ASP B OD1 1 ATOM 2772 O OD2 . ASP B 2 150 ? -30.097 -46.774 51.341 1.00 30.07 ? 150 ASP B OD2 1 ATOM 2773 N N . TYR B 2 151 ? -31.259 -46.611 45.404 1.00 18.22 ? 151 TYR B N 1 ATOM 2774 C CA . TYR B 2 151 ? -31.845 -47.315 44.268 1.00 16.69 ? 151 TYR B CA 1 ATOM 2775 C C . TYR B 2 151 ? -30.786 -47.627 43.218 1.00 17.24 ? 151 TYR B C 1 ATOM 2776 O O . TYR B 2 151 ? -29.669 -47.111 43.283 1.00 16.98 ? 151 TYR B O 1 ATOM 2777 C CB . TYR B 2 151 ? -32.997 -46.515 43.652 1.00 14.34 ? 151 TYR B CB 1 ATOM 2778 C CG . TYR B 2 151 ? -32.591 -45.158 43.117 1.00 12.77 ? 151 TYR B CG 1 ATOM 2779 C CD1 . TYR B 2 151 ? -32.544 -44.048 43.955 1.00 13.18 ? 151 TYR B CD1 1 ATOM 2780 C CD2 . TYR B 2 151 ? -32.256 -44.986 41.771 1.00 11.42 ? 151 TYR B CD2 1 ATOM 2781 C CE1 . TYR B 2 151 ? -32.171 -42.796 43.475 1.00 13.47 ? 151 TYR B CE1 1 ATOM 2782 C CE2 . TYR B 2 151 ? -31.904 -43.741 41.269 1.00 13.02 ? 151 TYR B CE2 1 ATOM 2783 C CZ . TYR B 2 151 ? -31.853 -42.647 42.129 1.00 18.15 ? 151 TYR B CZ 1 ATOM 2784 O OH . TYR B 2 151 ? -31.487 -41.406 41.654 1.00 15.50 ? 151 TYR B OH 1 ATOM 2785 N N . PHE B 2 152 ? -31.148 -48.490 42.272 1.00 14.45 ? 152 PHE B N 1 ATOM 2786 C CA . PHE B 2 152 ? -30.300 -48.840 41.145 1.00 15.77 ? 152 PHE B CA 1 ATOM 2787 C C . PHE B 2 152 ? -31.118 -49.553 40.062 1.00 20.95 ? 152 PHE B C 1 ATOM 2788 O O . PHE B 2 152 ? -32.005 -50.356 40.368 1.00 19.38 ? 152 PHE B O 1 ATOM 2789 C CB . PHE B 2 152 ? -29.159 -49.753 41.592 1.00 13.11 ? 152 PHE B CB 1 ATOM 2790 C CG . PHE B 2 152 ? -28.092 -49.908 40.564 1.00 15.89 ? 152 PHE B CG 1 ATOM 2791 C CD1 . PHE B 2 152 ? -28.068 -51.013 39.720 1.00 22.11 ? 152 PHE B CD1 1 ATOM 2792 C CD2 . PHE B 2 152 ? -27.121 -48.924 40.410 1.00 19.46 ? 152 PHE B CD2 1 ATOM 2793 C CE1 . PHE B 2 152 ? -27.075 -51.143 38.747 1.00 25.92 ? 152 PHE B CE1 1 ATOM 2794 C CE2 . PHE B 2 152 ? -26.131 -49.043 39.446 1.00 21.94 ? 152 PHE B CE2 1 ATOM 2795 C CZ . PHE B 2 152 ? -26.111 -50.156 38.612 1.00 19.08 ? 152 PHE B CZ 1 ATOM 2796 N N . PRO B 2 153 ? -30.836 -49.252 38.787 1.00 18.72 ? 153 PRO B N 1 ATOM 2797 C CA . PRO B 2 153 ? -29.946 -48.189 38.316 1.00 21.36 ? 153 PRO B CA 1 ATOM 2798 C C . PRO B 2 153 ? -30.716 -46.878 38.204 1.00 17.96 ? 153 PRO B C 1 ATOM 2799 O O . PRO B 2 153 ? -31.888 -46.849 38.551 1.00 17.48 ? 153 PRO B O 1 ATOM 2800 C CB . PRO B 2 153 ? -29.603 -48.662 36.902 1.00 25.48 ? 153 PRO B CB 1 ATOM 2801 C CG . PRO B 2 153 ? -30.880 -49.274 36.439 1.00 18.65 ? 153 PRO B CG 1 ATOM 2802 C CD . PRO B 2 153 ? -31.386 -50.026 37.658 1.00 17.77 ? 153 PRO B CD 1 ATOM 2803 N N . GLU B 2 154 ? -30.068 -45.822 37.721 1.00 21.63 ? 154 GLU B N 1 ATOM 2804 C CA . GLU B 2 154 ? -30.766 -44.627 37.269 1.00 17.03 ? 154 GLU B CA 1 ATOM 2805 C C . GLU B 2 154 ? -31.665 -45.052 36.105 1.00 21.54 ? 154 GLU B C 1 ATOM 2806 O O . GLU B 2 154 ? -31.455 -46.119 35.514 1.00 21.15 ? 154 GLU B O 1 ATOM 2807 C CB . GLU B 2 154 ? -29.759 -43.564 36.823 1.00 18.87 ? 154 GLU B CB 1 ATOM 2808 C CG . GLU B 2 154 ? -29.229 -42.662 37.953 1.00 21.96 ? 154 GLU B CG 1 ATOM 2809 C CD . GLU B 2 154 ? -29.990 -41.335 38.066 1.00 26.10 ? 154 GLU B CD 1 ATOM 2810 O OE1 . GLU B 2 154 ? -29.550 -40.344 37.450 1.00 31.34 ? 154 GLU B OE1 1 ATOM 2811 O OE2 . GLU B 2 154 ? -31.025 -41.278 38.773 1.00 25.81 ? 154 GLU B OE2 1 ATOM 2812 N N . PRO B 2 155 ? -32.681 -44.236 35.769 1.00 22.65 ? 155 PRO B N 1 ATOM 2813 C CA . PRO B 2 155 ? -33.078 -42.954 36.355 1.00 23.57 ? 155 PRO B CA 1 ATOM 2814 C C . PRO B 2 155 ? -34.213 -43.151 37.338 1.00 21.79 ? 155 PRO B C 1 ATOM 2815 O O . PRO B 2 155 ? -34.746 -44.261 37.459 1.00 22.62 ? 155 PRO B O 1 ATOM 2816 C CB . PRO B 2 155 ? -33.608 -42.191 35.142 1.00 15.11 ? 155 PRO B CB 1 ATOM 2817 C CG . PRO B 2 155 ? -34.251 -43.242 34.348 1.00 13.05 ? 155 PRO B CG 1 ATOM 2818 C CD . PRO B 2 155 ? -33.478 -44.521 34.569 1.00 19.37 ? 155 PRO B CD 1 ATOM 2819 N N . VAL B 2 156 ? -34.575 -42.082 38.032 1.00 17.53 ? 156 VAL B N 1 ATOM 2820 C CA . VAL B 2 156 ? -35.785 -42.083 38.829 1.00 19.24 ? 156 VAL B CA 1 ATOM 2821 C C . VAL B 2 156 ? -36.513 -40.790 38.509 1.00 18.02 ? 156 VAL B C 1 ATOM 2822 O O . VAL B 2 156 ? -35.883 -39.770 38.262 1.00 21.34 ? 156 VAL B O 1 ATOM 2823 C CB . VAL B 2 156 ? -35.482 -42.246 40.345 1.00 22.43 ? 156 VAL B CB 1 ATOM 2824 C CG1 . VAL B 2 156 ? -34.741 -41.039 40.894 1.00 16.70 ? 156 VAL B CG1 1 ATOM 2825 C CG2 . VAL B 2 156 ? -36.750 -42.469 41.113 1.00 21.24 ? 156 VAL B CG2 1 ATOM 2826 N N . THR B 2 157 ? -37.841 -40.817 38.469 1.00 21.49 ? 157 THR B N 1 ATOM 2827 C CA . THR B 2 157 ? -38.576 -39.584 38.197 1.00 16.73 ? 157 THR B CA 1 ATOM 2828 C C . THR B 2 157 ? -39.246 -39.079 39.458 1.00 19.46 ? 157 THR B C 1 ATOM 2829 O O . THR B 2 157 ? -39.700 -39.855 40.293 1.00 20.31 ? 157 THR B O 1 ATOM 2830 C CB . THR B 2 157 ? -39.601 -39.713 37.034 1.00 23.56 ? 157 THR B CB 1 ATOM 2831 O OG1 . THR B 2 157 ? -40.606 -40.673 37.371 1.00 36.43 ? 157 THR B OG1 1 ATOM 2832 C CG2 . THR B 2 157 ? -38.914 -40.161 35.768 1.00 25.01 ? 157 THR B CG2 1 ATOM 2833 N N . VAL B 2 158 ? -39.266 -37.764 39.606 1.00 19.67 ? 158 VAL B N 1 ATOM 2834 C CA . VAL B 2 158 ? -39.910 -37.144 40.739 1.00 18.35 ? 158 VAL B CA 1 ATOM 2835 C C . VAL B 2 158 ? -40.735 -35.986 40.230 1.00 23.78 ? 158 VAL B C 1 ATOM 2836 O O . VAL B 2 158 ? -40.251 -35.165 39.455 1.00 21.87 ? 158 VAL B O 1 ATOM 2837 C CB . VAL B 2 158 ? -38.900 -36.593 41.761 1.00 16.09 ? 158 VAL B CB 1 ATOM 2838 C CG1 . VAL B 2 158 ? -39.638 -35.930 42.922 1.00 15.00 ? 158 VAL B CG1 1 ATOM 2839 C CG2 . VAL B 2 158 ? -37.995 -37.689 42.263 1.00 19.45 ? 158 VAL B CG2 1 ATOM 2840 N N . SER B 2 159 ? -41.986 -35.925 40.675 1.00 20.97 ? 159 SER B N 1 ATOM 2841 C CA . SER B 2 159 ? -42.821 -34.770 40.438 1.00 20.16 ? 159 SER B CA 1 ATOM 2842 C C . SER B 2 159 ? -43.507 -34.430 41.748 1.00 22.69 ? 159 SER B C 1 ATOM 2843 O O . SER B 2 159 ? -43.439 -35.192 42.715 1.00 19.16 ? 159 SER B O 1 ATOM 2844 C CB . SER B 2 159 ? -43.851 -35.048 39.341 1.00 20.49 ? 159 SER B CB 1 ATOM 2845 O OG . SER B 2 159 ? -44.848 -35.930 39.802 1.00 28.82 ? 159 SER B OG 1 ATOM 2846 N N . TRP B 2 160 ? -44.155 -33.273 41.782 1.00 21.18 ? 160 TRP B N 1 ATOM 2847 C CA . TRP B 2 160 ? -44.860 -32.845 42.967 1.00 19.95 ? 160 TRP B CA 1 ATOM 2848 C C . TRP B 2 160 ? -46.337 -32.625 42.687 1.00 18.66 ? 160 TRP B C 1 ATOM 2849 O O . TRP B 2 160 ? -46.705 -32.050 41.653 1.00 22.16 ? 160 TRP B O 1 ATOM 2850 C CB . TRP B 2 160 ? -44.203 -31.598 43.516 1.00 17.70 ? 160 TRP B CB 1 ATOM 2851 C CG . TRP B 2 160 ? -42.868 -31.913 44.155 1.00 24.03 ? 160 TRP B CG 1 ATOM 2852 C CD1 . TRP B 2 160 ? -41.654 -32.001 43.535 1.00 16.15 ? 160 TRP B CD1 1 ATOM 2853 C CD2 . TRP B 2 160 ? -42.629 -32.181 45.543 1.00 18.59 ? 160 TRP B CD2 1 ATOM 2854 N NE1 . TRP B 2 160 ? -40.678 -32.297 44.450 1.00 13.94 ? 160 TRP B NE1 1 ATOM 2855 C CE2 . TRP B 2 160 ? -41.246 -32.411 45.689 1.00 16.88 ? 160 TRP B CE2 1 ATOM 2856 C CE3 . TRP B 2 160 ? -43.449 -32.247 46.670 1.00 16.46 ? 160 TRP B CE3 1 ATOM 2857 C CZ2 . TRP B 2 160 ? -40.667 -32.708 46.920 1.00 15.10 ? 160 TRP B CZ2 1 ATOM 2858 C CZ3 . TRP B 2 160 ? -42.875 -32.540 47.887 1.00 18.66 ? 160 TRP B CZ3 1 ATOM 2859 C CH2 . TRP B 2 160 ? -41.493 -32.763 48.006 1.00 19.69 ? 160 TRP B CH2 1 ATOM 2860 N N . ASN B 2 161 ? -47.168 -33.102 43.612 1.00 19.28 ? 161 ASN B N 1 ATOM 2861 C CA . ASN B 2 161 ? -48.621 -33.021 43.493 1.00 20.25 ? 161 ASN B CA 1 ATOM 2862 C C . ASN B 2 161 ? -49.080 -33.421 42.100 1.00 19.93 ? 161 ASN B C 1 ATOM 2863 O O . ASN B 2 161 ? -49.719 -32.644 41.394 1.00 23.15 ? 161 ASN B O 1 ATOM 2864 C CB . ASN B 2 161 ? -49.105 -31.624 43.866 1.00 16.38 ? 161 ASN B CB 1 ATOM 2865 C CG . ASN B 2 161 ? -48.811 -31.284 45.307 1.00 17.08 ? 161 ASN B CG 1 ATOM 2866 O OD1 . ASN B 2 161 ? -48.247 -32.096 46.043 1.00 27.43 ? 161 ASN B OD1 1 ATOM 2867 N ND2 . ASN B 2 161 ? -49.185 -30.082 45.725 1.00 17.61 ? 161 ASN B ND2 1 ATOM 2868 N N . SER B 2 162 ? -48.678 -34.621 41.697 1.00 21.14 ? 162 SER B N 1 ATOM 2869 C CA . SER B 2 162 ? -49.053 -35.215 40.405 1.00 26.07 ? 162 SER B CA 1 ATOM 2870 C C . SER B 2 162 ? -48.832 -34.329 39.194 1.00 18.87 ? 162 SER B C 1 ATOM 2871 O O . SER B 2 162 ? -49.602 -34.385 38.249 1.00 36.62 ? 162 SER B O 1 ATOM 2872 C CB . SER B 2 162 ? -50.512 -35.677 40.429 1.00 27.29 ? 162 SER B CB 1 ATOM 2873 O OG . SER B 2 162 ? -50.739 -36.547 41.526 1.00 25.29 ? 162 SER B OG 1 ATOM 2874 N N . GLY B 2 163 ? -47.787 -33.517 39.218 1.00 22.11 ? 163 GLY B N 1 ATOM 2875 C CA . GLY B 2 163 ? -47.521 -32.624 38.110 1.00 20.77 ? 163 GLY B CA 1 ATOM 2876 C C . GLY B 2 163 ? -48.050 -31.206 38.298 1.00 23.33 ? 163 GLY B C 1 ATOM 2877 O O . GLY B 2 163 ? -47.627 -30.304 37.582 1.00 25.72 ? 163 GLY B O 1 ATOM 2878 N N . ALA B 2 164 ? -48.957 -30.995 39.252 1.00 20.02 ? 164 ALA B N 1 ATOM 2879 C CA . ALA B 2 164 ? -49.539 -29.664 39.463 1.00 18.11 ? 164 ALA B CA 1 ATOM 2880 C C . ALA B 2 164 ? -48.585 -28.646 40.083 1.00 23.49 ? 164 ALA B C 1 ATOM 2881 O O . ALA B 2 164 ? -48.833 -27.451 39.996 1.00 32.06 ? 164 ALA B O 1 ATOM 2882 C CB . ALA B 2 164 ? -50.817 -29.754 40.306 1.00 13.00 ? 164 ALA B CB 1 ATOM 2883 N N . LEU B 2 165 ? -47.528 -29.111 40.745 1.00 22.12 ? 165 LEU B N 1 ATOM 2884 C CA . LEU B 2 165 ? -46.544 -28.203 41.344 1.00 21.95 ? 165 LEU B CA 1 ATOM 2885 C C . LEU B 2 165 ? -45.185 -28.341 40.651 1.00 17.74 ? 165 LEU B C 1 ATOM 2886 O O . LEU B 2 165 ? -44.559 -29.407 40.694 1.00 18.03 ? 165 LEU B O 1 ATOM 2887 C CB . LEU B 2 165 ? -46.420 -28.433 42.859 1.00 14.27 ? 165 LEU B CB 1 ATOM 2888 C CG . LEU B 2 165 ? -45.419 -27.559 43.632 1.00 24.90 ? 165 LEU B CG 1 ATOM 2889 C CD1 . LEU B 2 165 ? -45.682 -26.072 43.468 1.00 17.26 ? 165 LEU B CD1 1 ATOM 2890 C CD2 . LEU B 2 165 ? -45.381 -27.917 45.122 1.00 21.78 ? 165 LEU B CD2 1 ATOM 2891 N N . THR B 2 166 ? -44.742 -27.267 40.003 1.00 19.20 ? 166 THR B N 1 ATOM 2892 C CA . THR B 2 166 ? -43.482 -27.279 39.259 1.00 18.42 ? 166 THR B CA 1 ATOM 2893 C C . THR B 2 166 ? -42.627 -26.062 39.561 1.00 20.89 ? 166 THR B C 1 ATOM 2894 O O . THR B 2 166 ? -41.412 -26.085 39.411 1.00 25.81 ? 166 THR B O 1 ATOM 2895 C CB . THR B 2 166 ? -43.712 -27.313 37.730 1.00 21.29 ? 166 THR B CB 1 ATOM 2896 O OG1 . THR B 2 166 ? -44.681 -26.321 37.363 1.00 20.32 ? 166 THR B OG1 1 ATOM 2897 C CG2 . THR B 2 166 ? -44.195 -28.684 37.291 1.00 18.73 ? 166 THR B CG2 1 ATOM 2898 N N . SER B 2 167 ? -43.271 -24.985 39.971 1.00 19.27 ? 167 SER B N 1 ATOM 2899 C CA . SER B 2 167 ? -42.551 -23.780 40.285 1.00 20.31 ? 167 SER B CA 1 ATOM 2900 C C . SER B 2 167 ? -41.780 -23.949 41.618 1.00 30.44 ? 167 SER B C 1 ATOM 2901 O O . SER B 2 167 ? -42.344 -24.333 42.652 1.00 18.07 ? 167 SER B O 1 ATOM 2902 C CB . SER B 2 167 ? -43.534 -22.608 40.317 1.00 16.69 ? 167 SER B CB 1 ATOM 2903 O OG . SER B 2 167 ? -43.103 -21.601 41.209 1.00 34.58 ? 167 SER B OG 1 ATOM 2904 N N . GLY B 2 168 ? -40.478 -23.681 41.579 1.00 31.12 ? 168 GLY B N 1 ATOM 2905 C CA . GLY B 2 168 ? -39.663 -23.751 42.778 1.00 18.91 ? 168 GLY B CA 1 ATOM 2906 C C . GLY B 2 168 ? -39.193 -25.163 43.059 1.00 24.67 ? 168 GLY B C 1 ATOM 2907 O O . GLY B 2 168 ? -38.635 -25.429 44.122 1.00 22.51 ? 168 GLY B O 1 ATOM 2908 N N . VAL B 2 169 ? -39.426 -26.070 42.109 1.00 24.05 ? 169 VAL B N 1 ATOM 2909 C CA . VAL B 2 169 ? -38.959 -27.449 42.245 1.00 22.06 ? 169 VAL B CA 1 ATOM 2910 C C . VAL B 2 169 ? -37.520 -27.660 41.757 1.00 25.56 ? 169 VAL B C 1 ATOM 2911 O O . VAL B 2 169 ? -37.175 -27.352 40.605 1.00 28.90 ? 169 VAL B O 1 ATOM 2912 C CB . VAL B 2 169 ? -39.858 -28.428 41.502 1.00 20.84 ? 169 VAL B CB 1 ATOM 2913 C CG1 . VAL B 2 169 ? -39.306 -29.857 41.629 1.00 22.76 ? 169 VAL B CG1 1 ATOM 2914 C CG2 . VAL B 2 169 ? -41.281 -28.335 42.034 1.00 18.95 ? 169 VAL B CG2 1 ATOM 2915 N N . HIS B 2 170 ? -36.681 -28.197 42.633 1.00 20.04 ? 170 HIS B N 1 ATOM 2916 C CA . HIS B 2 170 ? -35.346 -28.629 42.229 1.00 16.95 ? 170 HIS B CA 1 ATOM 2917 C C . HIS B 2 170 ? -35.179 -30.091 42.550 1.00 19.92 ? 170 HIS B C 1 ATOM 2918 O O . HIS B 2 170 ? -35.241 -30.500 43.715 1.00 18.51 ? 170 HIS B O 1 ATOM 2919 C CB . HIS B 2 170 ? -34.262 -27.832 42.946 1.00 12.46 ? 170 HIS B CB 1 ATOM 2920 C CG . HIS B 2 170 ? -34.327 -26.369 42.655 1.00 17.84 ? 170 HIS B CG 1 ATOM 2921 N ND1 . HIS B 2 170 ? -34.252 -25.872 41.381 1.00 18.02 ? 170 HIS B ND1 1 ATOM 2922 C CD2 . HIS B 2 170 ? -34.489 -25.311 43.484 1.00 15.98 ? 170 HIS B CD2 1 ATOM 2923 C CE1 . HIS B 2 170 ? -34.356 -24.548 41.428 1.00 18.75 ? 170 HIS B CE1 1 ATOM 2924 N NE2 . HIS B 2 170 ? -34.495 -24.189 42.686 1.00 21.48 ? 170 HIS B NE2 1 ATOM 2925 N N . THR B 2 171 ? -34.977 -30.889 41.518 1.00 17.27 ? 171 THR B N 1 ATOM 2926 C CA . THR B 2 171 ? -34.642 -32.281 41.742 1.00 20.42 ? 171 THR B CA 1 ATOM 2927 C C . THR B 2 171 ? -33.167 -32.475 41.424 1.00 20.58 ? 171 THR B C 1 ATOM 2928 O O . THR B 2 171 ? -32.731 -32.270 40.292 1.00 22.09 ? 171 THR B O 1 ATOM 2929 C CB . THR B 2 171 ? -35.511 -33.197 40.896 1.00 16.58 ? 171 THR B CB 1 ATOM 2930 O OG1 . THR B 2 171 ? -36.871 -33.067 41.329 1.00 22.57 ? 171 THR B OG1 1 ATOM 2931 C CG2 . THR B 2 171 ? -35.051 -34.641 41.046 1.00 16.48 ? 171 THR B CG2 1 ATOM 2932 N N . PHE B 2 172 ? -32.394 -32.852 42.433 1.00 17.37 ? 172 PHE B N 1 ATOM 2933 C CA . PHE B 2 172 ? -30.942 -32.912 42.285 1.00 17.15 ? 172 PHE B CA 1 ATOM 2934 C C . PHE B 2 172 ? -30.473 -34.076 41.403 1.00 23.87 ? 172 PHE B C 1 ATOM 2935 O O . PHE B 2 172 ? -31.131 -35.118 41.311 1.00 19.02 ? 172 PHE B O 1 ATOM 2936 C CB . PHE B 2 172 ? -30.255 -32.862 43.660 1.00 14.60 ? 172 PHE B CB 1 ATOM 2937 C CG . PHE B 2 172 ? -30.385 -31.523 44.324 1.00 16.43 ? 172 PHE B CG 1 ATOM 2938 C CD1 . PHE B 2 172 ? -29.617 -30.449 43.897 1.00 23.73 ? 172 PHE B CD1 1 ATOM 2939 C CD2 . PHE B 2 172 ? -31.308 -31.311 45.320 1.00 9.79 ? 172 PHE B CD2 1 ATOM 2940 C CE1 . PHE B 2 172 ? -29.755 -29.189 44.481 1.00 23.21 ? 172 PHE B CE1 1 ATOM 2941 C CE2 . PHE B 2 172 ? -31.443 -30.060 45.905 1.00 15.36 ? 172 PHE B CE2 1 ATOM 2942 C CZ . PHE B 2 172 ? -30.673 -29.003 45.491 1.00 14.68 ? 172 PHE B CZ 1 ATOM 2943 N N . PRO B 2 173 ? -29.366 -33.872 40.686 1.00 19.06 ? 173 PRO B N 1 ATOM 2944 C CA . PRO B 2 173 ? -28.743 -34.998 39.997 1.00 21.35 ? 173 PRO B CA 1 ATOM 2945 C C . PRO B 2 173 ? -28.399 -36.057 41.034 1.00 24.84 ? 173 PRO B C 1 ATOM 2946 O O . PRO B 2 173 ? -27.965 -35.695 42.134 1.00 22.76 ? 173 PRO B O 1 ATOM 2947 C CB . PRO B 2 173 ? -27.474 -34.376 39.416 1.00 19.98 ? 173 PRO B CB 1 ATOM 2948 C CG . PRO B 2 173 ? -27.840 -32.967 39.173 1.00 17.65 ? 173 PRO B CG 1 ATOM 2949 C CD . PRO B 2 173 ? -28.751 -32.588 40.317 1.00 23.02 ? 173 PRO B CD 1 ATOM 2950 N N . ALA B 2 174 ? -28.626 -37.328 40.715 1.00 22.53 ? 174 ALA B N 1 ATOM 2951 C CA . ALA B 2 174 ? -28.296 -38.401 41.641 1.00 19.28 ? 174 ALA B CA 1 ATOM 2952 C C . ALA B 2 174 ? -26.792 -38.471 41.862 1.00 24.28 ? 174 ALA B C 1 ATOM 2953 O O . ALA B 2 174 ? -25.999 -38.060 41.015 1.00 22.04 ? 174 ALA B O 1 ATOM 2954 C CB . ALA B 2 174 ? -28.797 -39.731 41.114 1.00 21.77 ? 174 ALA B CB 1 ATOM 2955 N N . VAL B 2 175 ? -26.412 -38.974 43.024 1.00 26.51 ? 175 VAL B N 1 ATOM 2956 C CA . VAL B 2 175 ? -25.030 -39.265 43.312 1.00 21.18 ? 175 VAL B CA 1 ATOM 2957 C C . VAL B 2 175 ? -24.934 -40.742 43.632 1.00 22.99 ? 175 VAL B C 1 ATOM 2958 O O . VAL B 2 175 ? -25.871 -41.342 44.171 1.00 26.29 ? 175 VAL B O 1 ATOM 2959 C CB . VAL B 2 175 ? -24.496 -38.430 44.489 1.00 28.56 ? 175 VAL B CB 1 ATOM 2960 C CG1 . VAL B 2 175 ? -24.800 -36.935 44.267 1.00 19.99 ? 175 VAL B CG1 1 ATOM 2961 C CG2 . VAL B 2 175 ? -25.068 -38.928 45.822 1.00 26.42 ? 175 VAL B CG2 1 ATOM 2962 N N . LEU B 2 176 ? -23.812 -41.337 43.258 1.00 23.81 ? 176 LEU B N 1 ATOM 2963 C CA . LEU B 2 176 ? -23.543 -42.735 43.541 1.00 20.18 ? 176 LEU B CA 1 ATOM 2964 C C . LEU B 2 176 ? -22.892 -42.817 44.925 1.00 24.92 ? 176 LEU B C 1 ATOM 2965 O O . LEU B 2 176 ? -21.934 -42.102 45.217 1.00 26.88 ? 176 LEU B O 1 ATOM 2966 C CB . LEU B 2 176 ? -22.617 -43.302 42.465 1.00 17.98 ? 176 LEU B CB 1 ATOM 2967 C CG . LEU B 2 176 ? -22.474 -44.826 42.418 1.00 30.01 ? 176 LEU B CG 1 ATOM 2968 C CD1 . LEU B 2 176 ? -23.790 -45.501 41.988 1.00 20.75 ? 176 LEU B CD1 1 ATOM 2969 C CD2 . LEU B 2 176 ? -21.336 -45.226 41.500 1.00 23.94 ? 176 LEU B CD2 1 ATOM 2970 N N . GLN B 2 177 ? -23.428 -43.665 45.790 1.00 24.88 ? 177 GLN B N 1 ATOM 2971 C CA . GLN B 2 177 ? -22.870 -43.827 47.128 1.00 20.51 ? 177 GLN B CA 1 ATOM 2972 C C . GLN B 2 177 ? -21.833 -44.957 47.095 1.00 24.57 ? 177 GLN B C 1 ATOM 2973 O O . GLN B 2 177 ? -21.692 -45.660 46.091 1.00 22.35 ? 177 GLN B O 1 ATOM 2974 C CB . GLN B 2 177 ? -23.987 -44.123 48.137 1.00 21.79 ? 177 GLN B CB 1 ATOM 2975 C CG . GLN B 2 177 ? -25.109 -43.065 48.179 1.00 23.05 ? 177 GLN B CG 1 ATOM 2976 C CD . GLN B 2 177 ? -26.413 -43.575 48.823 1.00 25.52 ? 177 GLN B CD 1 ATOM 2977 O OE1 . GLN B 2 177 ? -26.846 -43.072 49.858 1.00 27.07 ? 177 GLN B OE1 1 ATOM 2978 N NE2 . GLN B 2 177 ? -27.041 -44.568 48.198 1.00 25.59 ? 177 GLN B NE2 1 ATOM 2979 N N . SER B 2 178 ? -21.104 -45.134 48.190 1.00 31.24 ? 178 SER B N 1 ATOM 2980 C CA . SER B 2 178 ? -20.068 -46.163 48.242 1.00 32.59 ? 178 SER B CA 1 ATOM 2981 C C . SER B 2 178 ? -20.708 -47.555 48.153 1.00 30.45 ? 178 SER B C 1 ATOM 2982 O O . SER B 2 178 ? -20.070 -48.537 47.764 1.00 33.95 ? 178 SER B O 1 ATOM 2983 C CB . SER B 2 178 ? -19.231 -46.030 49.523 1.00 29.58 ? 178 SER B CB 1 ATOM 2984 O OG . SER B 2 178 ? -19.949 -46.506 50.650 1.00 33.16 ? 178 SER B OG 1 ATOM 2985 N N . SER B 2 179 ? -21.982 -47.629 48.516 1.00 24.73 ? 179 SER B N 1 ATOM 2986 C CA . SER B 2 179 ? -22.735 -48.868 48.407 1.00 25.97 ? 179 SER B CA 1 ATOM 2987 C C . SER B 2 179 ? -22.947 -49.268 46.950 1.00 25.92 ? 179 SER B C 1 ATOM 2988 O O . SER B 2 179 ? -23.374 -50.381 46.673 1.00 21.15 ? 179 SER B O 1 ATOM 2989 C CB . SER B 2 179 ? -24.095 -48.696 49.054 1.00 17.93 ? 179 SER B CB 1 ATOM 2990 O OG . SER B 2 179 ? -24.878 -47.804 48.279 1.00 23.75 ? 179 SER B OG 1 ATOM 2991 N N . GLY B 2 180 ? -22.667 -48.356 46.025 1.00 20.50 ? 180 GLY B N 1 ATOM 2992 C CA . GLY B 2 180 ? -22.914 -48.617 44.621 1.00 22.40 ? 180 GLY B CA 1 ATOM 2993 C C . GLY B 2 180 ? -24.361 -48.331 44.246 1.00 22.04 ? 180 GLY B C 1 ATOM 2994 O O . GLY B 2 180 ? -24.804 -48.696 43.156 1.00 21.92 ? 180 GLY B O 1 ATOM 2995 N N . LEU B 2 181 ? -25.083 -47.678 45.156 1.00 16.71 ? 181 LEU B N 1 ATOM 2996 C CA . LEU B 2 181 ? -26.489 -47.344 44.981 1.00 15.76 ? 181 LEU B CA 1 ATOM 2997 C C . LEU B 2 181 ? -26.641 -45.837 44.899 1.00 19.72 ? 181 LEU B C 1 ATOM 2998 O O . LEU B 2 181 ? -25.849 -45.103 45.495 1.00 21.62 ? 181 LEU B O 1 ATOM 2999 C CB . LEU B 2 181 ? -27.302 -47.851 46.171 1.00 20.69 ? 181 LEU B CB 1 ATOM 3000 C CG . LEU B 2 181 ? -27.391 -49.364 46.372 1.00 19.25 ? 181 LEU B CG 1 ATOM 3001 C CD1 . LEU B 2 181 ? -28.310 -49.670 47.530 1.00 16.33 ? 181 LEU B CD1 1 ATOM 3002 C CD2 . LEU B 2 181 ? -27.890 -50.019 45.096 1.00 13.62 ? 181 LEU B CD2 1 ATOM 3003 N N . TYR B 2 182 ? -27.654 -45.376 44.168 1.00 17.37 ? 182 TYR B N 1 ATOM 3004 C CA . TYR B 2 182 ? -27.865 -43.946 43.978 1.00 17.28 ? 182 TYR B CA 1 ATOM 3005 C C . TYR B 2 182 ? -28.778 -43.329 45.018 1.00 16.97 ? 182 TYR B C 1 ATOM 3006 O O . TYR B 2 182 ? -29.637 -43.994 45.591 1.00 15.31 ? 182 TYR B O 1 ATOM 3007 C CB . TYR B 2 182 ? -28.445 -43.643 42.598 1.00 15.15 ? 182 TYR B CB 1 ATOM 3008 C CG . TYR B 2 182 ? -27.500 -43.867 41.445 1.00 21.90 ? 182 TYR B CG 1 ATOM 3009 C CD1 . TYR B 2 182 ? -27.502 -45.068 40.751 1.00 13.14 ? 182 TYR B CD1 1 ATOM 3010 C CD2 . TYR B 2 182 ? -26.619 -42.865 41.034 1.00 17.54 ? 182 TYR B CD2 1 ATOM 3011 C CE1 . TYR B 2 182 ? -26.663 -45.271 39.703 1.00 18.60 ? 182 TYR B CE1 1 ATOM 3012 C CE2 . TYR B 2 182 ? -25.765 -43.065 39.979 1.00 11.50 ? 182 TYR B CE2 1 ATOM 3013 C CZ . TYR B 2 182 ? -25.794 -44.273 39.317 1.00 19.57 ? 182 TYR B CZ 1 ATOM 3014 O OH . TYR B 2 182 ? -24.955 -44.503 38.255 1.00 24.77 ? 182 TYR B OH 1 ATOM 3015 N N . SER B 2 183 ? -28.601 -42.030 45.214 1.00 15.81 ? 183 SER B N 1 ATOM 3016 C CA . SER B 2 183 ? -29.445 -41.268 46.104 1.00 21.78 ? 183 SER B CA 1 ATOM 3017 C C . SER B 2 183 ? -29.647 -39.836 45.555 1.00 23.36 ? 183 SER B C 1 ATOM 3018 O O . SER B 2 183 ? -28.733 -39.255 44.978 1.00 25.85 ? 183 SER B O 1 ATOM 3019 C CB . SER B 2 183 ? -28.809 -41.247 47.491 1.00 16.11 ? 183 SER B CB 1 ATOM 3020 O OG . SER B 2 183 ? -29.563 -40.466 48.391 1.00 30.40 ? 183 SER B OG 1 ATOM 3021 N N . LEU B 2 184 ? -30.850 -39.285 45.700 1.00 24.05 ? 184 LEU B N 1 ATOM 3022 C CA . LEU B 2 184 ? -31.086 -37.882 45.373 1.00 19.41 ? 184 LEU B CA 1 ATOM 3023 C C . LEU B 2 184 ? -32.133 -37.258 46.288 1.00 20.28 ? 184 LEU B C 1 ATOM 3024 O O . LEU B 2 184 ? -32.936 -37.965 46.902 1.00 20.71 ? 184 LEU B O 1 ATOM 3025 C CB . LEU B 2 184 ? -31.487 -37.708 43.899 1.00 20.90 ? 184 LEU B CB 1 ATOM 3026 C CG . LEU B 2 184 ? -32.821 -38.213 43.316 1.00 18.39 ? 184 LEU B CG 1 ATOM 3027 C CD1 . LEU B 2 184 ? -34.009 -37.411 43.781 1.00 19.56 ? 184 LEU B CD1 1 ATOM 3028 C CD2 . LEU B 2 184 ? -32.771 -38.198 41.800 1.00 20.70 ? 184 LEU B CD2 1 ATOM 3029 N N . SER B 2 185 ? -32.122 -35.930 46.363 1.00 16.30 ? 185 SER B N 1 ATOM 3030 C CA . SER B 2 185 ? -33.213 -35.178 46.977 1.00 16.71 ? 185 SER B CA 1 ATOM 3031 C C . SER B 2 185 ? -33.935 -34.319 45.947 1.00 20.76 ? 185 SER B C 1 ATOM 3032 O O . SER B 2 185 ? -33.341 -33.857 44.972 1.00 20.49 ? 185 SER B O 1 ATOM 3033 C CB . SER B 2 185 ? -32.719 -34.288 48.117 1.00 16.39 ? 185 SER B CB 1 ATOM 3034 O OG . SER B 2 185 ? -32.508 -35.031 49.309 1.00 30.82 ? 185 SER B OG 1 ATOM 3035 N N . SER B 2 186 ? -35.228 -34.118 46.170 1.00 16.71 ? 186 SER B N 1 ATOM 3036 C CA . SER B 2 186 ? -36.015 -33.219 45.359 1.00 12.34 ? 186 SER B CA 1 ATOM 3037 C C . SER B 2 186 ? -36.628 -32.271 46.333 1.00 15.85 ? 186 SER B C 1 ATOM 3038 O O . SER B 2 186 ? -37.192 -32.710 47.319 1.00 21.48 ? 186 SER B O 1 ATOM 3039 C CB . SER B 2 186 ? -37.122 -33.978 44.635 1.00 17.80 ? 186 SER B CB 1 ATOM 3040 O OG . SER B 2 186 ? -37.821 -33.113 43.767 1.00 16.04 ? 186 SER B OG 1 ATOM 3041 N N . VAL B 2 187 ? -36.520 -30.974 46.077 1.00 15.67 ? 187 VAL B N 1 ATOM 3042 C CA . VAL B 2 187 ? -37.029 -29.991 47.018 1.00 18.66 ? 187 VAL B CA 1 ATOM 3043 C C . VAL B 2 187 ? -37.905 -28.999 46.311 1.00 13.87 ? 187 VAL B C 1 ATOM 3044 O O . VAL B 2 187 ? -37.871 -28.887 45.088 1.00 16.88 ? 187 VAL B O 1 ATOM 3045 C CB . VAL B 2 187 ? -35.890 -29.220 47.766 1.00 16.15 ? 187 VAL B CB 1 ATOM 3046 C CG1 . VAL B 2 187 ? -34.973 -30.193 48.467 1.00 16.16 ? 187 VAL B CG1 1 ATOM 3047 C CG2 . VAL B 2 187 ? -35.105 -28.339 46.802 1.00 14.98 ? 187 VAL B CG2 1 ATOM 3048 N N . VAL B 2 188 ? -38.690 -28.273 47.092 1.00 10.67 ? 188 VAL B N 1 ATOM 3049 C CA . VAL B 2 188 ? -39.545 -27.245 46.547 1.00 9.96 ? 188 VAL B CA 1 ATOM 3050 C C . VAL B 2 188 ? -39.707 -26.202 47.622 1.00 19.86 ? 188 VAL B C 1 ATOM 3051 O O . VAL B 2 188 ? -39.680 -26.525 48.821 1.00 19.50 ? 188 VAL B O 1 ATOM 3052 C CB . VAL B 2 188 ? -40.916 -27.814 46.113 1.00 17.21 ? 188 VAL B CB 1 ATOM 3053 C CG1 . VAL B 2 188 ? -41.614 -28.522 47.267 1.00 13.10 ? 188 VAL B CG1 1 ATOM 3054 C CG2 . VAL B 2 188 ? -41.810 -26.721 45.524 1.00 17.98 ? 188 VAL B CG2 1 ATOM 3055 N N . THR B 2 189 ? -39.822 -24.946 47.206 1.00 13.41 ? 189 THR B N 1 ATOM 3056 C CA . THR B 2 189 ? -40.143 -23.882 48.137 1.00 18.21 ? 189 THR B CA 1 ATOM 3057 C C . THR B 2 189 ? -41.585 -23.405 47.935 1.00 17.24 ? 189 THR B C 1 ATOM 3058 O O . THR B 2 189 ? -42.054 -23.236 46.816 1.00 20.76 ? 189 THR B O 1 ATOM 3059 C CB . THR B 2 189 ? -39.128 -22.712 48.077 1.00 21.30 ? 189 THR B CB 1 ATOM 3060 O OG1 . THR B 2 189 ? -38.895 -22.325 46.713 1.00 20.41 ? 189 THR B OG1 1 ATOM 3061 C CG2 . THR B 2 189 ? -37.820 -23.138 48.691 1.00 16.38 ? 189 THR B CG2 1 ATOM 3062 N N . VAL B 2 190 ? -42.289 -23.219 49.040 1.00 17.53 ? 190 VAL B N 1 ATOM 3063 C CA . VAL B 2 190 ? -43.699 -22.851 49.011 1.00 18.70 ? 190 VAL B CA 1 ATOM 3064 C C . VAL B 2 190 ? -43.943 -21.796 50.073 1.00 18.13 ? 190 VAL B C 1 ATOM 3065 O O . VAL B 2 190 ? -43.128 -21.637 50.987 1.00 25.15 ? 190 VAL B O 1 ATOM 3066 C CB . VAL B 2 190 ? -44.606 -24.078 49.299 1.00 21.41 ? 190 VAL B CB 1 ATOM 3067 C CG1 . VAL B 2 190 ? -44.362 -25.182 48.266 1.00 12.80 ? 190 VAL B CG1 1 ATOM 3068 C CG2 . VAL B 2 190 ? -44.388 -24.593 50.734 1.00 16.06 ? 190 VAL B CG2 1 ATOM 3069 N N . PRO B 2 191 ? -45.046 -21.049 49.951 1.00 19.63 ? 191 PRO B N 1 ATOM 3070 C CA . PRO B 2 191 ? -45.369 -20.133 51.049 1.00 26.71 ? 191 PRO B CA 1 ATOM 3071 C C . PRO B 2 191 ? -45.542 -20.912 52.348 1.00 21.06 ? 191 PRO B C 1 ATOM 3072 O O . PRO B 2 191 ? -46.199 -21.941 52.335 1.00 22.46 ? 191 PRO B O 1 ATOM 3073 C CB . PRO B 2 191 ? -46.705 -19.537 50.606 1.00 19.94 ? 191 PRO B CB 1 ATOM 3074 C CG . PRO B 2 191 ? -46.640 -19.586 49.113 1.00 14.63 ? 191 PRO B CG 1 ATOM 3075 C CD . PRO B 2 191 ? -45.975 -20.895 48.819 1.00 17.12 ? 191 PRO B CD 1 ATOM 3076 N N . SER B 2 192 ? -44.950 -20.447 53.441 1.00 19.73 ? 192 SER B N 1 ATOM 3077 C CA . SER B 2 192 ? -45.134 -21.131 54.713 1.00 28.31 ? 192 SER B CA 1 ATOM 3078 C C . SER B 2 192 ? -46.614 -21.150 55.127 1.00 24.49 ? 192 SER B C 1 ATOM 3079 O O . SER B 2 192 ? -47.063 -22.117 55.736 1.00 26.23 ? 192 SER B O 1 ATOM 3080 C CB . SER B 2 192 ? -44.255 -20.517 55.814 1.00 28.10 ? 192 SER B CB 1 ATOM 3081 O OG . SER B 2 192 ? -44.632 -19.180 56.087 1.00 32.77 ? 192 SER B OG 1 ATOM 3082 N N . SER B 2 193 ? -47.370 -20.103 54.774 1.00 21.74 ? 193 SER B N 1 ATOM 3083 C CA . SER B 2 193 ? -48.808 -20.041 55.107 1.00 22.43 ? 193 SER B CA 1 ATOM 3084 C C . SER B 2 193 ? -49.656 -21.134 54.458 1.00 21.16 ? 193 SER B C 1 ATOM 3085 O O . SER B 2 193 ? -50.799 -21.351 54.859 1.00 32.41 ? 193 SER B O 1 ATOM 3086 C CB . SER B 2 193 ? -49.427 -18.661 54.817 1.00 16.79 ? 193 SER B CB 1 ATOM 3087 O OG . SER B 2 193 ? -49.311 -18.288 53.452 1.00 24.71 ? 193 SER B OG 1 ATOM 3088 N N . SER B 2 194 ? -49.108 -21.829 53.471 1.00 20.53 ? 194 SER B N 1 ATOM 3089 C CA . SER B 2 194 ? -49.884 -22.848 52.782 1.00 20.13 ? 194 SER B CA 1 ATOM 3090 C C . SER B 2 194 ? -49.659 -24.224 53.389 1.00 30.39 ? 194 SER B C 1 ATOM 3091 O O . SER B 2 194 ? -50.333 -25.186 53.016 1.00 30.34 ? 194 SER B O 1 ATOM 3092 C CB . SER B 2 194 ? -49.540 -22.879 51.290 1.00 20.35 ? 194 SER B CB 1 ATOM 3093 O OG . SER B 2 194 ? -48.326 -23.584 51.079 1.00 25.36 ? 194 SER B OG 1 ATOM 3094 N N . LEU B 2 195 ? -48.702 -24.318 54.312 1.00 26.58 ? 195 LEU B N 1 ATOM 3095 C CA . LEU B 2 195 ? -48.369 -25.595 54.925 1.00 25.87 ? 195 LEU B CA 1 ATOM 3096 C C . LEU B 2 195 ? -49.546 -26.206 55.658 1.00 26.43 ? 195 LEU B C 1 ATOM 3097 O O . LEU B 2 195 ? -49.682 -27.421 55.704 1.00 38.12 ? 195 LEU B O 1 ATOM 3098 C CB . LEU B 2 195 ? -47.199 -25.456 55.884 1.00 22.86 ? 195 LEU B CB 1 ATOM 3099 C CG . LEU B 2 195 ? -45.838 -25.255 55.241 1.00 24.26 ? 195 LEU B CG 1 ATOM 3100 C CD1 . LEU B 2 195 ? -44.795 -25.117 56.338 1.00 21.00 ? 195 LEU B CD1 1 ATOM 3101 C CD2 . LEU B 2 195 ? -45.519 -26.411 54.312 1.00 23.10 ? 195 LEU B CD2 1 ATOM 3102 N N . GLY B 2 196 ? -50.394 -25.366 56.238 1.00 30.57 ? 196 GLY B N 1 ATOM 3103 C CA . GLY B 2 196 ? -51.580 -25.856 56.913 1.00 38.72 ? 196 GLY B CA 1 ATOM 3104 C C . GLY B 2 196 ? -52.657 -26.273 55.931 1.00 42.28 ? 196 GLY B C 1 ATOM 3105 O O . GLY B 2 196 ? -53.313 -27.300 56.101 1.00 47.69 ? 196 GLY B O 1 ATOM 3106 N N . THR B 2 197 ? -52.813 -25.473 54.884 1.00 37.51 ? 197 THR B N 1 ATOM 3107 C CA . THR B 2 197 ? -53.882 -25.643 53.910 1.00 40.13 ? 197 THR B CA 1 ATOM 3108 C C . THR B 2 197 ? -53.612 -26.730 52.865 1.00 38.31 ? 197 THR B C 1 ATOM 3109 O O . THR B 2 197 ? -54.462 -27.584 52.622 1.00 37.47 ? 197 THR B O 1 ATOM 3110 C CB . THR B 2 197 ? -54.128 -24.318 53.177 1.00 43.64 ? 197 THR B CB 1 ATOM 3111 O OG1 . THR B 2 197 ? -54.320 -23.280 54.146 1.00 43.47 ? 197 THR B OG1 1 ATOM 3112 C CG2 . THR B 2 197 ? -55.337 -24.417 52.249 1.00 40.52 ? 197 THR B CG2 1 ATOM 3113 N N . GLN B 2 198 ? -52.447 -26.706 52.263 1.00 36.34 ? 198 GLN B N 1 ATOM 3114 C CA . GLN B 2 198 ? -52.097 -27.527 51.123 1.00 25.05 ? 198 GLN B CA 1 ATOM 3115 C C . GLN B 2 198 ? -51.409 -28.828 51.459 1.00 24.49 ? 198 GLN B C 1 ATOM 3116 O O . GLN B 2 198 ? -50.657 -28.893 52.377 1.00 24.64 ? 198 GLN B O 1 ATOM 3117 C CB . GLN B 2 198 ? -51.170 -26.731 50.227 1.00 31.16 ? 198 GLN B CB 1 ATOM 3118 C CG . GLN B 2 198 ? -51.843 -25.727 49.353 1.00 38.14 ? 198 GLN B CG 1 ATOM 3119 C CD . GLN B 2 198 ? -52.751 -26.359 48.336 1.00 53.72 ? 198 GLN B CD 1 ATOM 3120 O OE1 . GLN B 2 198 ? -52.519 -27.484 47.874 1.00 43.43 ? 198 GLN B OE1 1 ATOM 3121 N NE2 . GLN B 2 198 ? -53.794 -25.642 47.980 1.00 41.59 ? 198 GLN B NE2 1 ATOM 3122 N N . THR B 2 199 ? -51.669 -29.864 50.695 1.00 23.59 ? 199 THR B N 1 ATOM 3123 C CA . THR B 2 199 ? -50.968 -31.125 50.857 1.00 24.18 ? 199 THR B CA 1 ATOM 3124 C C . THR B 2 199 ? -49.829 -31.195 49.849 1.00 21.10 ? 199 THR B C 1 ATOM 3125 O O . THR B 2 199 ? -50.001 -30.861 48.675 1.00 20.87 ? 199 THR B O 1 ATOM 3126 C CB . THR B 2 199 ? -51.922 -32.312 50.659 1.00 25.37 ? 199 THR B CB 1 ATOM 3127 O OG1 . THR B 2 199 ? -52.272 -32.420 49.275 1.00 19.69 ? 199 THR B OG1 1 ATOM 3128 C CG2 . THR B 2 199 ? -53.183 -32.091 51.474 1.00 28.52 ? 199 THR B CG2 1 ATOM 3129 N N . TYR B 2 200 ? -48.656 -31.616 50.304 1.00 21.36 ? 200 TYR B N 1 ATOM 3130 C CA . TYR B 2 200 ? -47.508 -31.694 49.410 1.00 15.97 ? 200 TYR B CA 1 ATOM 3131 C C . TYR B 2 200 ? -47.010 -33.118 49.292 1.00 20.47 ? 200 TYR B C 1 ATOM 3132 O O . TYR B 2 200 ? -46.657 -33.756 50.290 1.00 16.00 ? 200 TYR B O 1 ATOM 3133 C CB . TYR B 2 200 ? -46.402 -30.749 49.855 1.00 13.27 ? 200 TYR B CB 1 ATOM 3134 C CG . TYR B 2 200 ? -46.784 -29.289 49.710 1.00 16.62 ? 200 TYR B CG 1 ATOM 3135 C CD1 . TYR B 2 200 ? -46.701 -28.647 48.484 1.00 13.94 ? 200 TYR B CD1 1 ATOM 3136 C CD2 . TYR B 2 200 ? -47.243 -28.565 50.791 1.00 13.84 ? 200 TYR B CD2 1 ATOM 3137 C CE1 . TYR B 2 200 ? -47.053 -27.335 48.344 1.00 12.94 ? 200 TYR B CE1 1 ATOM 3138 C CE2 . TYR B 2 200 ? -47.597 -27.251 50.667 1.00 17.79 ? 200 TYR B CE2 1 ATOM 3139 C CZ . TYR B 2 200 ? -47.500 -26.634 49.441 1.00 18.10 ? 200 TYR B CZ 1 ATOM 3140 O OH . TYR B 2 200 ? -47.856 -25.315 49.319 1.00 8.04 ? 200 TYR B OH 1 ATOM 3141 N N . ILE B 2 201 ? -46.993 -33.614 48.056 1.00 19.33 ? 201 ILE B N 1 ATOM 3142 C CA . ILE B 2 201 ? -46.681 -35.005 47.801 1.00 13.69 ? 201 ILE B CA 1 ATOM 3143 C C . ILE B 2 201 ? -45.647 -35.112 46.712 1.00 19.56 ? 201 ILE B C 1 ATOM 3144 O O . ILE B 2 201 ? -45.858 -34.617 45.600 1.00 19.44 ? 201 ILE B O 1 ATOM 3145 C CB . ILE B 2 201 ? -47.946 -35.789 47.356 1.00 18.85 ? 201 ILE B CB 1 ATOM 3146 C CG1 . ILE B 2 201 ? -48.974 -35.803 48.500 1.00 21.03 ? 201 ILE B CG1 1 ATOM 3147 C CG2 . ILE B 2 201 ? -47.564 -37.196 46.899 1.00 15.49 ? 201 ILE B CG2 1 ATOM 3148 C CD1 . ILE B 2 201 ? -49.950 -36.944 48.474 1.00 22.10 ? 201 ILE B CD1 1 ATOM 3149 N N . CYS B 2 202 ? -44.524 -35.755 47.013 1.00 17.36 ? 202 CYS B N 1 ATOM 3150 C CA . CYS B 2 202 ? -43.579 -36.062 45.947 1.00 21.05 ? 202 CYS B CA 1 ATOM 3151 C C . CYS B 2 202 ? -43.918 -37.413 45.313 1.00 14.02 ? 202 CYS B C 1 ATOM 3152 O O . CYS B 2 202 ? -44.056 -38.413 46.006 1.00 19.27 ? 202 CYS B O 1 ATOM 3153 C CB . CYS B 2 202 ? -42.130 -36.011 46.437 1.00 21.75 ? 202 CYS B CB 1 ATOM 3154 S SG . CYS B 2 202 ? -41.671 -37.371 47.502 1.00 25.94 ? 202 CYS B SG 1 ATOM 3155 N N . ASN B 2 203 ? -44.082 -37.425 43.994 1.00 16.16 ? 203 ASN B N 1 ATOM 3156 C CA . ASN B 2 203 ? -44.414 -38.654 43.266 1.00 20.84 ? 203 ASN B CA 1 ATOM 3157 C C . ASN B 2 203 ? -43.163 -39.265 42.709 1.00 22.60 ? 203 ASN B C 1 ATOM 3158 O O . ASN B 2 203 ? -42.521 -38.689 41.843 1.00 24.17 ? 203 ASN B O 1 ATOM 3159 C CB . ASN B 2 203 ? -45.380 -38.362 42.135 1.00 8.36 ? 203 ASN B CB 1 ATOM 3160 C CG . ASN B 2 203 ? -46.488 -37.463 42.573 1.00 20.90 ? 203 ASN B CG 1 ATOM 3161 O OD1 . ASN B 2 203 ? -46.549 -36.308 42.171 1.00 23.84 ? 203 ASN B OD1 1 ATOM 3162 N ND2 . ASN B 2 203 ? -47.356 -37.967 43.444 1.00 19.00 ? 203 ASN B ND2 1 ATOM 3163 N N . VAL B 2 204 ? -42.810 -40.433 43.215 1.00 20.47 ? 204 VAL B N 1 ATOM 3164 C CA . VAL B 2 204 ? -41.548 -41.040 42.851 1.00 20.04 ? 204 VAL B CA 1 ATOM 3165 C C . VAL B 2 204 ? -41.795 -42.292 42.024 1.00 22.20 ? 204 VAL B C 1 ATOM 3166 O O . VAL B 2 204 ? -42.527 -43.183 42.436 1.00 19.07 ? 204 VAL B O 1 ATOM 3167 C CB . VAL B 2 204 ? -40.697 -41.357 44.102 1.00 15.11 ? 204 VAL B CB 1 ATOM 3168 C CG1 . VAL B 2 204 ? -39.433 -42.067 43.708 1.00 13.90 ? 204 VAL B CG1 1 ATOM 3169 C CG2 . VAL B 2 204 ? -40.388 -40.069 44.858 1.00 14.58 ? 204 VAL B CG2 1 ATOM 3170 N N . ASN B 2 205 ? -41.186 -42.342 40.845 1.00 21.97 ? 205 ASN B N 1 ATOM 3171 C CA . ASN B 2 205 ? -41.277 -43.515 40.003 1.00 20.81 ? 205 ASN B CA 1 ATOM 3172 C C . ASN B 2 205 ? -39.897 -44.018 39.631 1.00 22.21 ? 205 ASN B C 1 ATOM 3173 O O . ASN B 2 205 ? -39.100 -43.304 39.022 1.00 22.54 ? 205 ASN B O 1 ATOM 3174 C CB . ASN B 2 205 ? -42.104 -43.225 38.750 1.00 27.70 ? 205 ASN B CB 1 ATOM 3175 C CG . ASN B 2 205 ? -42.560 -44.497 38.047 1.00 31.18 ? 205 ASN B CG 1 ATOM 3176 O OD1 . ASN B 2 205 ? -42.205 -45.595 38.457 1.00 32.68 ? 205 ASN B OD1 1 ATOM 3177 N ND2 . ASN B 2 205 ? -43.371 -44.351 36.999 1.00 30.82 ? 205 ASN B ND2 1 ATOM 3178 N N . HIS B 2 206 ? -39.603 -45.241 40.042 1.00 19.79 ? 206 HIS B N 1 ATOM 3179 C CA . HIS B 2 206 ? -38.392 -45.911 39.607 1.00 22.81 ? 206 HIS B CA 1 ATOM 3180 C C . HIS B 2 206 ? -38.822 -46.984 38.624 1.00 24.23 ? 206 HIS B C 1 ATOM 3181 O O . HIS B 2 206 ? -39.088 -48.122 39.009 1.00 23.89 ? 206 HIS B O 1 ATOM 3182 C CB . HIS B 2 206 ? -37.649 -46.533 40.791 1.00 16.79 ? 206 HIS B CB 1 ATOM 3183 C CG . HIS B 2 206 ? -36.297 -47.075 40.442 1.00 22.07 ? 206 HIS B CG 1 ATOM 3184 N ND1 . HIS B 2 206 ? -35.940 -48.388 40.663 1.00 20.76 ? 206 HIS B ND1 1 ATOM 3185 C CD2 . HIS B 2 206 ? -35.208 -46.476 39.899 1.00 14.43 ? 206 HIS B CD2 1 ATOM 3186 C CE1 . HIS B 2 206 ? -34.690 -48.574 40.279 1.00 16.98 ? 206 HIS B CE1 1 ATOM 3187 N NE2 . HIS B 2 206 ? -34.226 -47.430 39.807 1.00 17.83 ? 206 HIS B NE2 1 ATOM 3188 N N . LYS B 2 207 ? -38.921 -46.600 37.358 1.00 23.61 ? 207 LYS B N 1 ATOM 3189 C CA . LYS B 2 207 ? -39.304 -47.540 36.314 1.00 25.81 ? 207 LYS B CA 1 ATOM 3190 C C . LYS B 2 207 ? -38.498 -48.854 36.249 1.00 20.90 ? 207 LYS B C 1 ATOM 3191 O O . LYS B 2 207 ? -39.098 -49.903 36.074 1.00 29.93 ? 207 LYS B O 1 ATOM 3192 C CB . LYS B 2 207 ? -39.388 -46.838 34.958 1.00 26.07 ? 207 LYS B CB 1 ATOM 3193 C CG . LYS B 2 207 ? -40.803 -46.398 34.619 1.00 29.77 ? 207 LYS B CG 1 ATOM 3194 C CD . LYS B 2 207 ? -40.854 -45.248 33.634 1.00 36.29 ? 207 LYS B CD 1 ATOM 3195 C CE . LYS B 2 207 ? -42.301 -44.917 33.288 1.00 50.56 ? 207 LYS B CE 1 ATOM 3196 N NZ . LYS B 2 207 ? -42.438 -43.584 32.650 1.00 37.41 ? 207 LYS B NZ 1 ATOM 3197 N N . PRO B 2 208 ? -37.159 -48.816 36.430 1.00 21.79 ? 208 PRO B N 1 ATOM 3198 C CA . PRO B 2 208 ? -36.435 -50.099 36.370 1.00 20.91 ? 208 PRO B CA 1 ATOM 3199 C C . PRO B 2 208 ? -36.846 -51.165 37.413 1.00 23.70 ? 208 PRO B C 1 ATOM 3200 O O . PRO B 2 208 ? -36.585 -52.351 37.199 1.00 22.18 ? 208 PRO B O 1 ATOM 3201 C CB . PRO B 2 208 ? -34.974 -49.689 36.597 1.00 17.36 ? 208 PRO B CB 1 ATOM 3202 C CG . PRO B 2 208 ? -34.908 -48.266 36.220 1.00 22.85 ? 208 PRO B CG 1 ATOM 3203 C CD . PRO B 2 208 ? -36.232 -47.676 36.583 1.00 21.67 ? 208 PRO B CD 1 ATOM 3204 N N . SER B 2 209 ? -37.459 -50.755 38.520 1.00 23.84 ? 209 SER B N 1 ATOM 3205 C CA . SER B 2 209 ? -37.837 -51.697 39.581 1.00 26.68 ? 209 SER B CA 1 ATOM 3206 C C . SER B 2 209 ? -39.346 -51.697 39.808 1.00 31.48 ? 209 SER B C 1 ATOM 3207 O O . SER B 2 209 ? -39.844 -52.331 40.742 1.00 22.09 ? 209 SER B O 1 ATOM 3208 C CB . SER B 2 209 ? -37.129 -51.374 40.902 1.00 21.64 ? 209 SER B CB 1 ATOM 3209 O OG . SER B 2 209 ? -37.659 -50.215 41.510 1.00 24.99 ? 209 SER B OG 1 ATOM 3210 N N . ASN B 2 210 ? -40.069 -50.988 38.942 1.00 30.05 ? 210 ASN B N 1 ATOM 3211 C CA . ASN B 2 210 ? -41.529 -50.873 39.049 1.00 33.05 ? 210 ASN B CA 1 ATOM 3212 C C . ASN B 2 210 ? -41.981 -50.376 40.414 1.00 31.49 ? 210 ASN B C 1 ATOM 3213 O O . ASN B 2 210 ? -43.006 -50.806 40.926 1.00 34.85 ? 210 ASN B O 1 ATOM 3214 C CB . ASN B 2 210 ? -42.197 -52.205 38.719 1.00 34.75 ? 210 ASN B CB 1 ATOM 3215 C CG . ASN B 2 210 ? -41.933 -52.635 37.299 1.00 47.21 ? 210 ASN B CG 1 ATOM 3216 O OD1 . ASN B 2 210 ? -42.078 -51.840 36.356 1.00 40.89 ? 210 ASN B OD1 1 ATOM 3217 N ND2 . ASN B 2 210 ? -41.526 -53.891 37.129 1.00 40.52 ? 210 ASN B ND2 1 ATOM 3218 N N . THR B 2 211 ? -41.195 -49.477 40.996 1.00 35.92 ? 211 THR B N 1 ATOM 3219 C CA . THR B 2 211 ? -41.525 -48.889 42.273 1.00 26.61 ? 211 THR B CA 1 ATOM 3220 C C . THR B 2 211 ? -42.125 -47.507 42.064 1.00 29.34 ? 211 THR B C 1 ATOM 3221 O O . THR B 2 211 ? -41.457 -46.585 41.595 1.00 25.66 ? 211 THR B O 1 ATOM 3222 C CB . THR B 2 211 ? -40.295 -48.760 43.168 1.00 27.29 ? 211 THR B CB 1 ATOM 3223 O OG1 . THR B 2 211 ? -39.689 -50.046 43.341 1.00 32.14 ? 211 THR B OG1 1 ATOM 3224 C CG2 . THR B 2 211 ? -40.687 -48.176 44.542 1.00 24.89 ? 211 THR B CG2 1 ATOM 3225 N N . LYS B 2 212 ? -43.404 -47.382 42.389 1.00 27.37 ? 212 LYS B N 1 ATOM 3226 C CA . LYS B 2 212 ? -44.052 -46.082 42.437 1.00 28.13 ? 212 LYS B CA 1 ATOM 3227 C C . LYS B 2 212 ? -44.403 -45.765 43.881 1.00 20.50 ? 212 LYS B C 1 ATOM 3228 O O . LYS B 2 212 ? -45.037 -46.564 44.561 1.00 17.69 ? 212 LYS B O 1 ATOM 3229 C CB . LYS B 2 212 ? -45.289 -46.052 41.538 1.00 17.17 ? 212 LYS B CB 1 ATOM 3230 C CG . LYS B 2 212 ? -44.987 -45.612 40.132 1.00 28.00 ? 212 LYS B CG 1 ATOM 3231 C CD . LYS B 2 212 ? -46.198 -45.718 39.201 1.00 33.34 ? 212 LYS B CD 1 ATOM 3232 C CE . LYS B 2 212 ? -47.378 -44.888 39.697 1.00 31.07 ? 212 LYS B CE 1 ATOM 3233 N NZ . LYS B 2 212 ? -48.378 -44.624 38.612 1.00 38.36 ? 212 LYS B NZ 1 ATOM 3234 N N . VAL B 2 213 ? -43.960 -44.607 44.351 1.00 18.81 ? 213 VAL B N 1 ATOM 3235 C CA . VAL B 2 213 ? -44.264 -44.185 45.706 1.00 20.28 ? 213 VAL B CA 1 ATOM 3236 C C . VAL B 2 213 ? -44.746 -42.752 45.723 1.00 18.16 ? 213 VAL B C 1 ATOM 3237 O O . VAL B 2 213 ? -44.161 -41.895 45.078 1.00 20.90 ? 213 VAL B O 1 ATOM 3238 C CB . VAL B 2 213 ? -43.045 -44.312 46.634 1.00 19.04 ? 213 VAL B CB 1 ATOM 3239 C CG1 . VAL B 2 213 ? -43.344 -43.692 47.999 1.00 19.42 ? 213 VAL B CG1 1 ATOM 3240 C CG2 . VAL B 2 213 ? -42.654 -45.766 46.791 1.00 14.84 ? 213 VAL B CG2 1 ATOM 3241 N N . ASP B 2 214 ? -45.825 -42.502 46.457 1.00 22.14 ? 214 ASP B N 1 ATOM 3242 C CA . ASP B 2 214 ? -46.256 -41.138 46.751 1.00 19.35 ? 214 ASP B CA 1 ATOM 3243 C C . ASP B 2 214 ? -45.978 -40.864 48.223 1.00 20.66 ? 214 ASP B C 1 ATOM 3244 O O . ASP B 2 214 ? -46.580 -41.485 49.106 1.00 21.57 ? 214 ASP B O 1 ATOM 3245 C CB . ASP B 2 214 ? -47.744 -40.941 46.451 1.00 16.82 ? 214 ASP B CB 1 ATOM 3246 C CG . ASP B 2 214 ? -48.036 -40.876 44.951 1.00 25.57 ? 214 ASP B CG 1 ATOM 3247 O OD1 . ASP B 2 214 ? -47.096 -40.610 44.157 1.00 21.02 ? 214 ASP B OD1 1 ATOM 3248 O OD2 . ASP B 2 214 ? -49.206 -41.089 44.562 1.00 24.03 ? 214 ASP B OD2 1 ATOM 3249 N N . LYS B 2 215 ? -45.067 -39.935 48.481 1.00 17.79 ? 215 LYS B N 1 ATOM 3250 C CA . LYS B 2 215 ? -44.707 -39.574 49.839 1.00 15.71 ? 215 LYS B CA 1 ATOM 3251 C C . LYS B 2 215 ? -45.270 -38.220 50.189 1.00 14.87 ? 215 LYS B C 1 ATOM 3252 O O . LYS B 2 215 ? -44.911 -37.227 49.571 1.00 18.82 ? 215 LYS B O 1 ATOM 3253 C CB . LYS B 2 215 ? -43.192 -39.506 49.994 1.00 16.87 ? 215 LYS B CB 1 ATOM 3254 C CG . LYS B 2 215 ? -42.754 -39.132 51.414 1.00 18.11 ? 215 LYS B CG 1 ATOM 3255 C CD . LYS B 2 215 ? -42.757 -40.356 52.316 1.00 20.67 ? 215 LYS B CD 1 ATOM 3256 C CE . LYS B 2 215 ? -43.178 -40.015 53.722 1.00 18.11 ? 215 LYS B CE 1 ATOM 3257 N NZ . LYS B 2 215 ? -43.317 -41.279 54.484 1.00 20.27 ? 215 LYS B NZ 1 ATOM 3258 N N . ARG B 2 216 ? -46.134 -38.182 51.192 1.00 13.02 ? 216 ARG B N 1 ATOM 3259 C CA . ARG B 2 216 ? -46.646 -36.928 51.715 1.00 16.39 ? 216 ARG B CA 1 ATOM 3260 C C . ARG B 2 216 ? -45.624 -36.325 52.666 1.00 14.27 ? 216 ARG B C 1 ATOM 3261 O O . ARG B 2 216 ? -45.063 -37.030 53.498 1.00 15.99 ? 216 ARG B O 1 ATOM 3262 C CB . ARG B 2 216 ? -47.977 -37.169 52.439 1.00 21.66 ? 216 ARG B CB 1 ATOM 3263 C CG . ARG B 2 216 ? -48.432 -36.031 53.330 1.00 18.03 ? 216 ARG B CG 1 ATOM 3264 C CD . ARG B 2 216 ? -49.080 -34.915 52.533 1.00 17.95 ? 216 ARG B CD 1 ATOM 3265 N NE . ARG B 2 216 ? -49.665 -33.932 53.438 1.00 30.89 ? 216 ARG B NE 1 ATOM 3266 C CZ . ARG B 2 216 ? -50.873 -34.042 53.985 1.00 36.12 ? 216 ARG B CZ 1 ATOM 3267 N NH1 . ARG B 2 216 ? -51.633 -35.095 53.700 1.00 27.71 ? 216 ARG B NH1 1 ATOM 3268 N NH2 . ARG B 2 216 ? -51.320 -33.098 54.809 1.00 31.25 ? 216 ARG B NH2 1 ATOM 3269 N N . VAL B 2 217 ? -45.389 -35.023 52.541 1.00 16.40 ? 217 VAL B N 1 ATOM 3270 C CA . VAL B 2 217 ? -44.378 -34.334 53.348 1.00 18.13 ? 217 VAL B CA 1 ATOM 3271 C C . VAL B 2 217 ? -45.023 -33.225 54.182 1.00 25.67 ? 217 VAL B C 1 ATOM 3272 O O . VAL B 2 217 ? -45.592 -32.275 53.630 1.00 20.90 ? 217 VAL B O 1 ATOM 3273 C CB . VAL B 2 217 ? -43.289 -33.706 52.469 1.00 14.25 ? 217 VAL B CB 1 ATOM 3274 C CG1 . VAL B 2 217 ? -42.329 -32.904 53.319 1.00 17.76 ? 217 VAL B CG1 1 ATOM 3275 C CG2 . VAL B 2 217 ? -42.544 -34.796 51.675 1.00 9.62 ? 217 VAL B CG2 1 ATOM 3276 N N . GLU B 2 218 ? -44.916 -33.342 55.508 1.00 22.19 ? 218 GLU B N 1 ATOM 3277 C CA . GLU B 2 218 ? -45.639 -32.480 56.450 1.00 29.42 ? 218 GLU B CA 1 ATOM 3278 C C . GLU B 2 218 ? -44.674 -31.872 57.439 1.00 24.42 ? 218 GLU B C 1 ATOM 3279 O O . GLU B 2 218 ? -43.624 -32.439 57.692 1.00 24.63 ? 218 GLU B O 1 ATOM 3280 C CB . GLU B 2 218 ? -46.675 -33.298 57.232 1.00 28.03 ? 218 GLU B CB 1 ATOM 3281 C CG . GLU B 2 218 ? -47.986 -33.515 56.506 1.00 39.22 ? 218 GLU B CG 1 ATOM 3282 C CD . GLU B 2 218 ? -48.824 -34.621 57.138 1.00 53.34 ? 218 GLU B CD 1 ATOM 3283 O OE1 . GLU B 2 218 ? -49.852 -35.021 56.538 1.00 48.57 ? 218 GLU B OE1 1 ATOM 3284 O OE2 . GLU B 2 218 ? -48.452 -35.099 58.232 1.00 40.81 ? 218 GLU B OE2 1 ATOM 3285 N N . PRO B 2 219 ? -45.037 -30.720 58.023 1.00 35.66 ? 219 PRO B N 1 ATOM 3286 C CA . PRO B 2 219 ? -44.227 -30.114 59.090 1.00 27.19 ? 219 PRO B CA 1 ATOM 3287 C C . PRO B 2 219 ? -44.166 -31.043 60.295 1.00 30.86 ? 219 PRO B C 1 ATOM 3288 O O . PRO B 2 219 ? -45.187 -31.663 60.582 1.00 31.41 ? 219 PRO B O 1 ATOM 3289 C CB . PRO B 2 219 ? -45.022 -28.862 59.461 1.00 20.91 ? 219 PRO B CB 1 ATOM 3290 C CG . PRO B 2 219 ? -45.881 -28.574 58.263 1.00 27.96 ? 219 PRO B CG 1 ATOM 3291 C CD . PRO B 2 219 ? -46.220 -29.906 57.683 1.00 21.77 ? 219 PRO B CD 1 ATOM 3292 N N . LYS B 2 220 ? -43.020 -31.143 60.978 1.00 40.20 ? 220 LYS B N 1 ATOM 3293 C CA . LYS B 2 220 ? -42.919 -31.995 62.170 1.00 39.05 ? 220 LYS B CA 1 ATOM 3294 C C . LYS B 2 220 ? -43.127 -31.206 63.449 1.00 43.52 ? 220 LYS B C 1 ATOM 3295 O O . LYS B 2 220 ? -44.212 -31.233 64.031 1.00 54.33 ? 220 LYS B O 1 ATOM 3296 C CB . LYS B 2 220 ? -41.582 -32.738 62.230 1.00 50.10 ? 220 LYS B CB 1 ATOM 3297 C CG . LYS B 2 220 ? -41.704 -34.247 62.000 1.00 59.89 ? 220 LYS B CG 1 ATOM 3298 C CD . LYS B 2 220 ? -40.469 -35.010 62.489 1.00 60.63 ? 220 LYS B CD 1 ATOM 3299 C CE . LYS B 2 220 ? -40.319 -34.935 64.004 1.00 55.10 ? 220 LYS B CE 1 ATOM 3300 N NZ . LYS B 2 220 ? -39.451 -36.020 64.553 1.00 52.25 ? 220 LYS B NZ 1 ATOM 3301 N N . ASP C 1 1 ? -17.110 0.717 6.118 1.00 33.00 ? 1 ASP C N 1 ATOM 3302 C CA . ASP C 1 1 ? -15.967 -0.148 6.350 1.00 29.34 ? 1 ASP C CA 1 ATOM 3303 C C . ASP C 1 1 ? -16.359 -1.621 6.432 1.00 41.42 ? 1 ASP C C 1 ATOM 3304 O O . ASP C 1 1 ? -17.527 -1.956 6.639 1.00 40.55 ? 1 ASP C O 1 ATOM 3305 C CB . ASP C 1 1 ? -15.248 0.252 7.640 1.00 32.87 ? 1 ASP C CB 1 ATOM 3306 C CG . ASP C 1 1 ? -14.673 1.638 7.583 1.00 47.21 ? 1 ASP C CG 1 ATOM 3307 O OD1 . ASP C 1 1 ? -14.783 2.284 6.521 1.00 40.68 ? 1 ASP C OD1 1 ATOM 3308 O OD2 . ASP C 1 1 ? -14.099 2.075 8.612 1.00 59.78 ? 1 ASP C OD2 1 ATOM 3309 N N . ILE C 1 2 ? -15.369 -2.493 6.260 1.00 31.19 ? 2 ILE C N 1 ATOM 3310 C CA . ILE C 1 2 ? -15.568 -3.918 6.466 1.00 32.48 ? 2 ILE C CA 1 ATOM 3311 C C . ILE C 1 2 ? -15.625 -4.204 7.964 1.00 29.82 ? 2 ILE C C 1 ATOM 3312 O O . ILE C 1 2 ? -14.713 -3.821 8.709 1.00 26.94 ? 2 ILE C O 1 ATOM 3313 C CB . ILE C 1 2 ? -14.408 -4.727 5.853 1.00 30.11 ? 2 ILE C CB 1 ATOM 3314 C CG1 . ILE C 1 2 ? -14.357 -4.507 4.339 1.00 31.25 ? 2 ILE C CG1 1 ATOM 3315 C CG2 . ILE C 1 2 ? -14.543 -6.213 6.187 1.00 19.29 ? 2 ILE C CG2 1 ATOM 3316 C CD1 . ILE C 1 2 ? -15.508 -5.122 3.595 1.00 24.55 ? 2 ILE C CD1 1 ATOM 3317 N N . LEU C 1 3 ? -16.685 -4.874 8.409 1.00 25.41 ? 3 LEU C N 1 ATOM 3318 C CA . LEU C 1 3 ? -16.750 -5.312 9.799 1.00 25.07 ? 3 LEU C CA 1 ATOM 3319 C C . LEU C 1 3 ? -16.129 -6.702 9.971 1.00 25.74 ? 3 LEU C C 1 ATOM 3320 O O . LEU C 1 3 ? -16.395 -7.617 9.190 1.00 32.19 ? 3 LEU C O 1 ATOM 3321 C CB . LEU C 1 3 ? -18.191 -5.302 10.317 1.00 24.10 ? 3 LEU C CB 1 ATOM 3322 C CG . LEU C 1 3 ? -18.276 -5.478 11.845 1.00 39.68 ? 3 LEU C CG 1 ATOM 3323 C CD1 . LEU C 1 3 ? -17.777 -4.219 12.567 1.00 24.62 ? 3 LEU C CD1 1 ATOM 3324 C CD2 . LEU C 1 3 ? -19.686 -5.887 12.335 1.00 21.37 ? 3 LEU C CD2 1 ATOM 3325 N N . LEU C 1 4 ? -15.283 -6.855 10.979 1.00 22.44 ? 4 LEU C N 1 ATOM 3326 C CA . LEU C 1 4 ? -14.748 -8.166 11.297 1.00 21.52 ? 4 LEU C CA 1 ATOM 3327 C C . LEU C 1 4 ? -15.332 -8.625 12.625 1.00 31.42 ? 4 LEU C C 1 ATOM 3328 O O . LEU C 1 4 ? -15.253 -7.916 13.639 1.00 22.32 ? 4 LEU C O 1 ATOM 3329 C CB . LEU C 1 4 ? -13.224 -8.136 11.387 1.00 22.07 ? 4 LEU C CB 1 ATOM 3330 C CG . LEU C 1 4 ? -12.417 -7.660 10.175 1.00 23.71 ? 4 LEU C CG 1 ATOM 3331 C CD1 . LEU C 1 4 ? -10.932 -7.776 10.467 1.00 23.74 ? 4 LEU C CD1 1 ATOM 3332 C CD2 . LEU C 1 4 ? -12.780 -8.412 8.908 1.00 16.86 ? 4 LEU C CD2 1 ATOM 3333 N N . THR C 1 5 ? -15.922 -9.812 12.617 1.00 21.28 ? 5 THR C N 1 ATOM 3334 C CA . THR C 1 5 ? -16.516 -10.353 13.819 1.00 20.35 ? 5 THR C CA 1 ATOM 3335 C C . THR C 1 5 ? -15.669 -11.507 14.301 1.00 21.32 ? 5 THR C C 1 ATOM 3336 O O . THR C 1 5 ? -15.599 -12.540 13.642 1.00 30.29 ? 5 THR C O 1 ATOM 3337 C CB . THR C 1 5 ? -17.963 -10.834 13.567 1.00 26.40 ? 5 THR C CB 1 ATOM 3338 O OG1 . THR C 1 5 ? -18.736 -9.760 13.029 1.00 31.79 ? 5 THR C OG1 1 ATOM 3339 C CG2 . THR C 1 5 ? -18.617 -11.272 14.851 1.00 19.67 ? 5 THR C CG2 1 ATOM 3340 N N . GLN C 1 6 ? -15.015 -11.334 15.441 1.00 17.98 ? 6 GLN C N 1 ATOM 3341 C CA . GLN C 1 6 ? -14.210 -12.414 15.997 1.00 24.56 ? 6 GLN C CA 1 ATOM 3342 C C . GLN C 1 6 ? -14.997 -13.183 17.044 1.00 32.43 ? 6 GLN C C 1 ATOM 3343 O O . GLN C 1 6 ? -15.809 -12.606 17.763 1.00 32.36 ? 6 GLN C O 1 ATOM 3344 C CB . GLN C 1 6 ? -12.918 -11.881 16.607 1.00 21.27 ? 6 GLN C CB 1 ATOM 3345 C CG . GLN C 1 6 ? -11.917 -11.425 15.594 1.00 18.97 ? 6 GLN C CG 1 ATOM 3346 C CD . GLN C 1 6 ? -10.656 -10.908 16.238 1.00 20.37 ? 6 GLN C CD 1 ATOM 3347 O OE1 . GLN C 1 6 ? -10.424 -9.704 16.297 1.00 21.51 ? 6 GLN C OE1 1 ATOM 3348 N NE2 . GLN C 1 6 ? -9.834 -11.819 16.733 1.00 22.05 ? 6 GLN C NE2 1 ATOM 3349 N N . SER C 1 7 ? -14.772 -14.488 17.120 1.00 26.50 ? 7 SER C N 1 ATOM 3350 C CA . SER C 1 7 ? -15.464 -15.296 18.118 1.00 28.00 ? 7 SER C CA 1 ATOM 3351 C C . SER C 1 7 ? -14.628 -16.507 18.540 1.00 30.73 ? 7 SER C C 1 ATOM 3352 O O . SER C 1 7 ? -13.895 -17.081 17.729 1.00 33.60 ? 7 SER C O 1 ATOM 3353 C CB . SER C 1 7 ? -16.839 -15.736 17.599 1.00 31.34 ? 7 SER C CB 1 ATOM 3354 O OG . SER C 1 7 ? -16.726 -16.833 16.706 1.00 36.05 ? 7 SER C OG 1 ATOM 3355 N N . PRO C 1 8 ? -14.731 -16.897 19.817 1.00 32.29 ? 8 PRO C N 1 ATOM 3356 C CA . PRO C 1 8 ? -15.570 -16.232 20.820 1.00 34.85 ? 8 PRO C CA 1 ATOM 3357 C C . PRO C 1 8 ? -14.868 -15.012 21.405 1.00 29.01 ? 8 PRO C C 1 ATOM 3358 O O . PRO C 1 8 ? -13.690 -14.780 21.135 1.00 27.00 ? 8 PRO C O 1 ATOM 3359 C CB . PRO C 1 8 ? -15.710 -17.298 21.904 1.00 26.93 ? 8 PRO C CB 1 ATOM 3360 C CG . PRO C 1 8 ? -14.392 -18.007 21.861 1.00 26.18 ? 8 PRO C CG 1 ATOM 3361 C CD . PRO C 1 8 ? -14.014 -18.056 20.385 1.00 24.40 ? 8 PRO C CD 1 ATOM 3362 N N . VAL C 1 9 ? -15.599 -14.234 22.189 1.00 27.16 ? 9 VAL C N 1 ATOM 3363 C CA . VAL C 1 9 ? -15.013 -13.114 22.906 1.00 30.88 ? 9 VAL C CA 1 ATOM 3364 C C . VAL C 1 9 ? -13.942 -13.631 23.873 1.00 29.11 ? 9 VAL C C 1 ATOM 3365 O O . VAL C 1 9 ? -12.853 -13.064 23.979 1.00 29.91 ? 9 VAL C O 1 ATOM 3366 C CB . VAL C 1 9 ? -16.095 -12.335 23.669 1.00 32.05 ? 9 VAL C CB 1 ATOM 3367 C CG1 . VAL C 1 9 ? -15.475 -11.273 24.549 1.00 40.98 ? 9 VAL C CG1 1 ATOM 3368 C CG2 . VAL C 1 9 ? -17.079 -11.730 22.697 1.00 21.53 ? 9 VAL C CG2 1 ATOM 3369 N N . ILE C 1 10 ? -14.257 -14.723 24.561 1.00 27.41 ? 10 ILE C N 1 ATOM 3370 C CA . ILE C 1 10 ? -13.325 -15.342 25.488 1.00 25.60 ? 10 ILE C CA 1 ATOM 3371 C C . ILE C 1 10 ? -13.162 -16.815 25.166 1.00 31.18 ? 10 ILE C C 1 ATOM 3372 O O . ILE C 1 10 ? -14.146 -17.568 25.091 1.00 26.09 ? 10 ILE C O 1 ATOM 3373 C CB . ILE C 1 10 ? -13.817 -15.252 26.940 1.00 25.33 ? 10 ILE C CB 1 ATOM 3374 C CG1 . ILE C 1 10 ? -14.133 -13.810 27.327 1.00 31.56 ? 10 ILE C CG1 1 ATOM 3375 C CG2 . ILE C 1 10 ? -12.787 -15.849 27.873 1.00 24.10 ? 10 ILE C CG2 1 ATOM 3376 C CD1 . ILE C 1 10 ? -14.624 -13.675 28.743 1.00 39.44 ? 10 ILE C CD1 1 ATOM 3377 N N . LEU C 1 11 ? -11.913 -17.227 24.994 1.00 26.07 ? 11 LEU C N 1 ATOM 3378 C CA . LEU C 1 11 ? -11.611 -18.589 24.602 1.00 21.09 ? 11 LEU C CA 1 ATOM 3379 C C . LEU C 1 11 ? -10.828 -19.296 25.698 1.00 21.91 ? 11 LEU C C 1 ATOM 3380 O O . LEU C 1 11 ? -9.627 -19.107 25.833 1.00 26.82 ? 11 LEU C O 1 ATOM 3381 C CB . LEU C 1 11 ? -10.837 -18.586 23.280 1.00 22.30 ? 11 LEU C CB 1 ATOM 3382 C CG . LEU C 1 11 ? -10.360 -19.911 22.698 1.00 27.36 ? 11 LEU C CG 1 ATOM 3383 C CD1 . LEU C 1 11 ? -11.499 -20.917 22.694 1.00 35.39 ? 11 LEU C CD1 1 ATOM 3384 C CD2 . LEU C 1 11 ? -9.835 -19.691 21.285 1.00 31.16 ? 11 LEU C CD2 1 ATOM 3385 N N . SER C 1 12 ? -11.521 -20.108 26.485 1.00 24.12 ? 12 SER C N 1 ATOM 3386 C CA . SER C 1 12 ? -10.882 -20.846 27.566 1.00 26.61 ? 12 SER C CA 1 ATOM 3387 C C . SER C 1 12 ? -10.549 -22.269 27.109 1.00 25.13 ? 12 SER C C 1 ATOM 3388 O O . SER C 1 12 ? -11.419 -22.986 26.615 1.00 26.55 ? 12 SER C O 1 ATOM 3389 C CB . SER C 1 12 ? -11.808 -20.868 28.794 1.00 23.87 ? 12 SER C CB 1 ATOM 3390 O OG . SER C 1 12 ? -11.193 -21.494 29.907 1.00 34.20 ? 12 SER C OG 1 ATOM 3391 N N . VAL C 1 13 ? -9.292 -22.673 27.258 1.00 20.19 ? 13 VAL C N 1 ATOM 3392 C CA . VAL C 1 13 ? -8.870 -24.000 26.814 1.00 27.01 ? 13 VAL C CA 1 ATOM 3393 C C . VAL C 1 13 ? -7.822 -24.614 27.717 1.00 26.51 ? 13 VAL C C 1 ATOM 3394 O O . VAL C 1 13 ? -7.124 -23.911 28.436 1.00 30.78 ? 13 VAL C O 1 ATOM 3395 C CB . VAL C 1 13 ? -8.260 -23.982 25.389 1.00 32.02 ? 13 VAL C CB 1 ATOM 3396 C CG1 . VAL C 1 13 ? -9.305 -23.641 24.342 1.00 33.52 ? 13 VAL C CG1 1 ATOM 3397 C CG2 . VAL C 1 13 ? -7.079 -23.020 25.330 1.00 28.22 ? 13 VAL C CG2 1 ATOM 3398 N N . SER C 1 14 ? -7.693 -25.934 27.640 1.00 30.24 ? 14 SER C N 1 ATOM 3399 C CA . SER C 1 14 ? -6.712 -26.664 28.434 1.00 33.69 ? 14 SER C CA 1 ATOM 3400 C C . SER C 1 14 ? -5.372 -26.711 27.707 1.00 30.30 ? 14 SER C C 1 ATOM 3401 O O . SER C 1 14 ? -5.326 -26.830 26.495 1.00 36.68 ? 14 SER C O 1 ATOM 3402 C CB . SER C 1 14 ? -7.209 -28.080 28.728 1.00 28.86 ? 14 SER C CB 1 ATOM 3403 O OG . SER C 1 14 ? -8.503 -28.044 29.298 1.00 41.88 ? 14 SER C OG 1 ATOM 3404 N N . PRO C 1 15 ? -4.268 -26.621 28.453 1.00 38.06 ? 15 PRO C N 1 ATOM 3405 C CA . PRO C 1 15 ? -2.955 -26.578 27.800 1.00 31.45 ? 15 PRO C CA 1 ATOM 3406 C C . PRO C 1 15 ? -2.664 -27.835 26.981 1.00 31.36 ? 15 PRO C C 1 ATOM 3407 O O . PRO C 1 15 ? -3.075 -28.931 27.368 1.00 34.65 ? 15 PRO C O 1 ATOM 3408 C CB . PRO C 1 15 ? -1.979 -26.446 28.980 1.00 27.77 ? 15 PRO C CB 1 ATOM 3409 C CG . PRO C 1 15 ? -2.733 -26.950 30.157 1.00 26.88 ? 15 PRO C CG 1 ATOM 3410 C CD . PRO C 1 15 ? -4.163 -26.596 29.923 1.00 32.65 ? 15 PRO C CD 1 ATOM 3411 N N . GLY C 1 16 ? -1.974 -27.669 25.855 1.00 31.69 ? 16 GLY C N 1 ATOM 3412 C CA . GLY C 1 16 ? -1.660 -28.782 24.976 1.00 22.75 ? 16 GLY C CA 1 ATOM 3413 C C . GLY C 1 16 ? -2.754 -29.073 23.964 1.00 31.60 ? 16 GLY C C 1 ATOM 3414 O O . GLY C 1 16 ? -2.534 -29.810 23.010 1.00 30.82 ? 16 GLY C O 1 ATOM 3415 N N . GLU C 1 17 ? -3.934 -28.495 24.171 1.00 32.13 ? 17 GLU C N 1 ATOM 3416 C CA . GLU C 1 17 ? -5.040 -28.650 23.232 1.00 30.50 ? 17 GLU C CA 1 ATOM 3417 C C . GLU C 1 17 ? -4.832 -27.872 21.931 1.00 33.30 ? 17 GLU C C 1 ATOM 3418 O O . GLU C 1 17 ? -3.935 -27.038 21.819 1.00 27.40 ? 17 GLU C O 1 ATOM 3419 C CB . GLU C 1 17 ? -6.354 -28.198 23.872 1.00 32.04 ? 17 GLU C CB 1 ATOM 3420 C CG . GLU C 1 17 ? -6.938 -29.162 24.885 1.00 34.83 ? 17 GLU C CG 1 ATOM 3421 C CD . GLU C 1 17 ? -8.301 -28.718 25.373 1.00 38.39 ? 17 GLU C CD 1 ATOM 3422 O OE1 . GLU C 1 17 ? -8.529 -27.491 25.453 1.00 38.51 ? 17 GLU C OE1 1 ATOM 3423 O OE2 . GLU C 1 17 ? -9.147 -29.592 25.671 1.00 51.69 ? 17 GLU C OE2 1 ATOM 3424 N N . ARG C 1 18 ? -5.678 -28.156 20.948 1.00 48.22 ? 18 ARG C N 1 ATOM 3425 C CA . ARG C 1 18 ? -5.719 -27.373 19.720 1.00 48.38 ? 18 ARG C CA 1 ATOM 3426 C C . ARG C 1 18 ? -6.702 -26.218 19.902 1.00 37.46 ? 18 ARG C C 1 ATOM 3427 O O . ARG C 1 18 ? -7.744 -26.373 20.541 1.00 34.39 ? 18 ARG C O 1 ATOM 3428 C CB . ARG C 1 18 ? -6.112 -28.251 18.531 1.00 43.57 ? 18 ARG C CB 1 ATOM 3429 C CG . ARG C 1 18 ? -6.120 -27.518 17.204 1.00 53.20 ? 18 ARG C CG 1 ATOM 3430 C CD . ARG C 1 18 ? -5.955 -28.478 16.038 1.00 56.82 ? 18 ARG C CD 1 ATOM 3431 N NE . ARG C 1 18 ? -6.020 -27.784 14.755 1.00 62.35 ? 18 ARG C NE 1 ATOM 3432 C CZ . ARG C 1 18 ? -4.983 -27.188 14.173 1.00 63.88 ? 18 ARG C CZ 1 ATOM 3433 N NH1 . ARG C 1 18 ? -3.796 -27.196 14.761 1.00 58.75 ? 18 ARG C NH1 1 ATOM 3434 N NH2 . ARG C 1 18 ? -5.132 -26.578 13.005 1.00 56.54 ? 18 ARG C NH2 1 ATOM 3435 N N . VAL C 1 19 ? -6.363 -25.059 19.351 1.00 26.54 ? 19 VAL C N 1 ATOM 3436 C CA . VAL C 1 19 ? -7.115 -23.841 19.611 1.00 25.85 ? 19 VAL C CA 1 ATOM 3437 C C . VAL C 1 19 ? -7.458 -23.129 18.311 1.00 23.96 ? 19 VAL C C 1 ATOM 3438 O O . VAL C 1 19 ? -6.602 -22.977 17.434 1.00 27.64 ? 19 VAL C O 1 ATOM 3439 C CB . VAL C 1 19 ? -6.305 -22.916 20.541 1.00 32.83 ? 19 VAL C CB 1 ATOM 3440 C CG1 . VAL C 1 19 ? -6.863 -21.514 20.553 1.00 24.89 ? 19 VAL C CG1 1 ATOM 3441 C CG2 . VAL C 1 19 ? -6.261 -23.504 21.941 1.00 35.27 ? 19 VAL C CG2 1 ATOM 3442 N N . SER C 1 20 ? -8.712 -22.701 18.172 1.00 30.26 ? 20 SER C N 1 ATOM 3443 C CA . SER C 1 20 ? -9.135 -22.061 16.926 1.00 24.14 ? 20 SER C CA 1 ATOM 3444 C C . SER C 1 20 ? -9.891 -20.757 17.102 1.00 32.62 ? 20 SER C C 1 ATOM 3445 O O . SER C 1 20 ? -11.038 -20.730 17.560 1.00 35.41 ? 20 SER C O 1 ATOM 3446 C CB . SER C 1 20 ? -9.928 -23.027 16.064 1.00 26.89 ? 20 SER C CB 1 ATOM 3447 O OG . SER C 1 20 ? -9.078 -24.064 15.605 1.00 38.45 ? 20 SER C OG 1 ATOM 3448 N N . PHE C 1 21 ? -9.231 -19.669 16.724 1.00 32.84 ? 21 PHE C N 1 ATOM 3449 C CA . PHE C 1 21 ? -9.857 -18.363 16.776 1.00 30.04 ? 21 PHE C CA 1 ATOM 3450 C C . PHE C 1 21 ? -10.611 -18.139 15.485 1.00 28.89 ? 21 PHE C C 1 ATOM 3451 O O . PHE C 1 21 ? -10.141 -18.499 14.408 1.00 27.89 ? 21 PHE C O 1 ATOM 3452 C CB . PHE C 1 21 ? -8.814 -17.276 16.967 1.00 23.50 ? 21 PHE C CB 1 ATOM 3453 C CG . PHE C 1 21 ? -7.920 -17.496 18.162 1.00 22.30 ? 21 PHE C CG 1 ATOM 3454 C CD1 . PHE C 1 21 ? -6.721 -18.161 18.032 1.00 24.31 ? 21 PHE C CD1 1 ATOM 3455 C CD2 . PHE C 1 21 ? -8.272 -17.016 19.400 1.00 18.15 ? 21 PHE C CD2 1 ATOM 3456 C CE1 . PHE C 1 21 ? -5.894 -18.344 19.118 1.00 26.61 ? 21 PHE C CE1 1 ATOM 3457 C CE2 . PHE C 1 21 ? -7.454 -17.191 20.484 1.00 21.64 ? 21 PHE C CE2 1 ATOM 3458 C CZ . PHE C 1 21 ? -6.265 -17.857 20.351 1.00 26.20 ? 21 PHE C CZ 1 ATOM 3459 N N . SER C 1 22 ? -11.785 -17.535 15.589 1.00 27.96 ? 22 SER C N 1 ATOM 3460 C CA . SER C 1 22 ? -12.643 -17.380 14.427 1.00 28.97 ? 22 SER C CA 1 ATOM 3461 C C . SER C 1 22 ? -12.821 -15.910 14.071 1.00 23.49 ? 22 SER C C 1 ATOM 3462 O O . SER C 1 22 ? -13.060 -15.080 14.942 1.00 27.26 ? 22 SER C O 1 ATOM 3463 C CB . SER C 1 22 ? -13.982 -18.060 14.687 1.00 22.34 ? 22 SER C CB 1 ATOM 3464 O OG . SER C 1 22 ? -14.954 -17.613 13.785 1.00 31.53 ? 22 SER C OG 1 ATOM 3465 N N . CYS C 1 23 ? -12.682 -15.598 12.787 1.00 19.86 ? 23 CYS C N 1 ATOM 3466 C CA . CYS C 1 23 ? -12.834 -14.230 12.296 1.00 25.20 ? 23 CYS C CA 1 ATOM 3467 C C . CYS C 1 23 ? -13.724 -14.239 11.049 1.00 34.21 ? 23 CYS C C 1 ATOM 3468 O O . CYS C 1 23 ? -13.394 -14.866 10.033 1.00 32.60 ? 23 CYS C O 1 ATOM 3469 C CB . CYS C 1 23 ? -11.463 -13.609 11.982 1.00 21.30 ? 23 CYS C CB 1 ATOM 3470 S SG . CYS C 1 23 ? -11.458 -11.854 11.468 1.00 28.44 ? 23 CYS C SG 1 ATOM 3471 N N . ARG C 1 24 ? -14.859 -13.560 11.125 1.00 24.89 ? 24 ARG C N 1 ATOM 3472 C CA . ARG C 1 24 ? -15.770 -13.536 9.998 1.00 25.35 ? 24 ARG C CA 1 ATOM 3473 C C . ARG C 1 24 ? -15.845 -12.112 9.465 1.00 30.86 ? 24 ARG C C 1 ATOM 3474 O O . ARG C 1 24 ? -15.998 -11.159 10.241 1.00 27.44 ? 24 ARG C O 1 ATOM 3475 C CB . ARG C 1 24 ? -17.155 -14.031 10.425 1.00 29.53 ? 24 ARG C CB 1 ATOM 3476 C CG . ARG C 1 24 ? -18.074 -14.379 9.262 1.00 49.82 ? 24 ARG C CG 1 ATOM 3477 C CD . ARG C 1 24 ? -19.367 -15.089 9.703 1.00 49.09 ? 24 ARG C CD 1 ATOM 3478 N NE . ARG C 1 24 ? -19.899 -15.927 8.625 1.00 63.23 ? 24 ARG C NE 1 ATOM 3479 C CZ . ARG C 1 24 ? -20.679 -15.493 7.636 1.00 62.55 ? 24 ARG C CZ 1 ATOM 3480 N NH1 . ARG C 1 24 ? -21.042 -14.218 7.570 1.00 63.14 ? 24 ARG C NH1 1 ATOM 3481 N NH2 . ARG C 1 24 ? -21.099 -16.344 6.709 1.00 54.43 ? 24 ARG C NH2 1 ATOM 3482 N N . ALA C 1 25 ? -15.724 -11.963 8.147 1.00 27.13 ? 25 ALA C N 1 ATOM 3483 C CA . ALA C 1 25 ? -15.805 -10.645 7.523 1.00 25.76 ? 25 ALA C CA 1 ATOM 3484 C C . ALA C 1 25 ? -17.225 -10.338 7.039 1.00 33.23 ? 25 ALA C C 1 ATOM 3485 O O . ALA C 1 25 ? -17.977 -11.243 6.673 1.00 37.43 ? 25 ALA C O 1 ATOM 3486 C CB . ALA C 1 25 ? -14.804 -10.520 6.400 1.00 23.58 ? 25 ALA C CB 1 ATOM 3487 N N . SER C 1 26 ? -17.584 -9.056 7.049 1.00 32.32 ? 26 SER C N 1 ATOM 3488 C CA . SER C 1 26 ? -18.938 -8.628 6.720 1.00 28.55 ? 26 SER C CA 1 ATOM 3489 C C . SER C 1 26 ? -19.237 -8.792 5.230 1.00 38.52 ? 26 SER C C 1 ATOM 3490 O O . SER C 1 26 ? -20.392 -8.695 4.806 1.00 38.34 ? 26 SER C O 1 ATOM 3491 C CB . SER C 1 26 ? -19.194 -7.186 7.186 1.00 27.00 ? 26 SER C CB 1 ATOM 3492 O OG . SER C 1 26 ? -18.337 -6.254 6.548 1.00 33.90 ? 26 SER C OG 1 ATOM 3493 N N . GLN C 1 27 ? -18.187 -9.048 4.456 1.00 31.51 ? 27 GLN C N 1 ATOM 3494 C CA . GLN C 1 27 ? -18.294 -9.367 3.032 1.00 35.67 ? 27 GLN C CA 1 ATOM 3495 C C . GLN C 1 27 ? -16.998 -10.052 2.584 1.00 35.04 ? 27 GLN C C 1 ATOM 3496 O O . GLN C 1 27 ? -16.030 -10.104 3.340 1.00 34.74 ? 27 GLN C O 1 ATOM 3497 C CB . GLN C 1 27 ? -18.540 -8.104 2.207 1.00 34.99 ? 27 GLN C CB 1 ATOM 3498 C CG . GLN C 1 27 ? -17.282 -7.423 1.746 1.00 36.91 ? 27 GLN C CG 1 ATOM 3499 C CD . GLN C 1 27 ? -17.549 -6.109 1.041 1.00 51.25 ? 27 GLN C CD 1 ATOM 3500 O OE1 . GLN C 1 27 ? -18.426 -5.342 1.449 1.00 45.80 ? 27 GLN C OE1 1 ATOM 3501 N NE2 . GLN C 1 27 ? -16.788 -5.839 -0.028 1.00 42.28 ? 27 GLN C NE2 1 ATOM 3502 N N . SER C 1 28 ? -16.963 -10.573 1.364 1.00 32.56 ? 28 SER C N 1 ATOM 3503 C CA . SER C 1 28 ? -15.764 -11.270 0.900 1.00 35.49 ? 28 SER C CA 1 ATOM 3504 C C . SER C 1 28 ? -14.519 -10.385 0.831 1.00 32.88 ? 28 SER C C 1 ATOM 3505 O O . SER C 1 28 ? -14.576 -9.234 0.403 1.00 29.29 ? 28 SER C O 1 ATOM 3506 C CB . SER C 1 28 ? -15.992 -11.932 -0.454 1.00 32.00 ? 28 SER C CB 1 ATOM 3507 O OG . SER C 1 28 ? -14.885 -12.752 -0.781 1.00 43.35 ? 28 SER C OG 1 ATOM 3508 N N . ILE C 1 29 ? -13.396 -10.947 1.263 1.00 30.11 ? 29 ILE C N 1 ATOM 3509 C CA . ILE C 1 29 ? -12.129 -10.239 1.277 1.00 24.29 ? 29 ILE C CA 1 ATOM 3510 C C . ILE C 1 29 ? -10.978 -11.134 0.845 1.00 25.24 ? 29 ILE C C 1 ATOM 3511 O O . ILE C 1 29 ? -9.826 -10.861 1.169 1.00 28.13 ? 29 ILE C O 1 ATOM 3512 C CB . ILE C 1 29 ? -11.801 -9.683 2.681 1.00 21.16 ? 29 ILE C CB 1 ATOM 3513 C CG1 . ILE C 1 29 ? -11.915 -10.782 3.726 1.00 20.18 ? 29 ILE C CG1 1 ATOM 3514 C CG2 . ILE C 1 29 ? -12.672 -8.477 3.026 1.00 23.15 ? 29 ILE C CG2 1 ATOM 3515 C CD1 . ILE C 1 29 ? -11.374 -10.379 5.067 1.00 28.30 ? 29 ILE C CD1 1 ATOM 3516 N N . GLY C 1 30 ? -11.293 -12.211 0.135 1.00 23.99 ? 30 GLY C N 1 ATOM 3517 C CA . GLY C 1 30 ? -10.269 -13.077 -0.425 1.00 19.43 ? 30 GLY C CA 1 ATOM 3518 C C . GLY C 1 30 ? -9.443 -13.775 0.633 1.00 23.04 ? 30 GLY C C 1 ATOM 3519 O O . GLY C 1 30 ? -9.971 -14.539 1.443 1.00 32.96 ? 30 GLY C O 1 ATOM 3520 N N . THR C 1 31 ? -8.142 -13.522 0.629 1.00 18.49 ? 31 THR C N 1 ATOM 3521 C CA . THR C 1 31 ? -7.288 -14.017 1.700 1.00 21.15 ? 31 THR C CA 1 ATOM 3522 C C . THR C 1 31 ? -6.580 -12.844 2.372 1.00 20.38 ? 31 THR C C 1 ATOM 3523 O O . THR C 1 31 ? -5.511 -12.998 2.942 1.00 19.65 ? 31 THR C O 1 ATOM 3524 C CB . THR C 1 31 ? -6.254 -15.050 1.193 1.00 27.38 ? 31 THR C CB 1 ATOM 3525 O OG1 . THR C 1 31 ? -5.417 -14.455 0.195 1.00 25.20 ? 31 THR C OG1 1 ATOM 3526 C CG2 . THR C 1 31 ? -6.946 -16.270 0.606 1.00 21.12 ? 31 THR C CG2 1 ATOM 3527 N N . ASN C 1 32 ? -7.201 -11.671 2.303 1.00 25.83 ? 32 ASN C N 1 ATOM 3528 C CA . ASN C 1 32 ? -6.576 -10.439 2.756 1.00 19.96 ? 32 ASN C CA 1 ATOM 3529 C C . ASN C 1 32 ? -6.805 -10.172 4.241 1.00 20.07 ? 32 ASN C C 1 ATOM 3530 O O . ASN C 1 32 ? -7.383 -9.159 4.631 1.00 25.60 ? 32 ASN C O 1 ATOM 3531 C CB . ASN C 1 32 ? -7.063 -9.268 1.918 1.00 19.30 ? 32 ASN C CB 1 ATOM 3532 C CG . ASN C 1 32 ? -5.980 -8.235 1.682 1.00 28.97 ? 32 ASN C CG 1 ATOM 3533 O OD1 . ASN C 1 32 ? -5.259 -7.845 2.604 1.00 32.34 ? 32 ASN C OD1 1 ATOM 3534 N ND2 . ASN C 1 32 ? -5.856 -7.785 0.438 1.00 34.15 ? 32 ASN C ND2 1 ATOM 3535 N N . ILE C 1 33 ? -6.333 -11.094 5.067 1.00 19.35 ? 33 ILE C N 1 ATOM 3536 C CA . ILE C 1 33 ? -6.526 -11.006 6.503 1.00 18.03 ? 33 ILE C CA 1 ATOM 3537 C C . ILE C 1 33 ? -5.180 -11.252 7.179 1.00 22.90 ? 33 ILE C C 1 ATOM 3538 O O . ILE C 1 33 ? -4.400 -12.086 6.732 1.00 19.31 ? 33 ILE C O 1 ATOM 3539 C CB . ILE C 1 33 ? -7.598 -12.011 6.974 1.00 19.56 ? 33 ILE C CB 1 ATOM 3540 C CG1 . ILE C 1 33 ? -8.004 -11.762 8.420 1.00 26.00 ? 33 ILE C CG1 1 ATOM 3541 C CG2 . ILE C 1 33 ? -7.117 -13.427 6.796 1.00 28.61 ? 33 ILE C CG2 1 ATOM 3542 C CD1 . ILE C 1 33 ? -9.289 -10.936 8.541 1.00 32.17 ? 33 ILE C CD1 1 ATOM 3543 N N . HIS C 1 34 ? -4.883 -10.474 8.215 1.00 19.52 ? 34 HIS C N 1 ATOM 3544 C CA . HIS C 1 34 ? -3.668 -10.665 9.002 1.00 17.96 ? 34 HIS C CA 1 ATOM 3545 C C . HIS C 1 34 ? -4.024 -10.906 10.477 1.00 20.47 ? 34 HIS C C 1 ATOM 3546 O O . HIS C 1 34 ? -5.064 -10.457 10.955 1.00 16.79 ? 34 HIS C O 1 ATOM 3547 C CB . HIS C 1 34 ? -2.738 -9.465 8.865 1.00 21.99 ? 34 HIS C CB 1 ATOM 3548 C CG . HIS C 1 34 ? -2.510 -9.030 7.448 1.00 27.81 ? 34 HIS C CG 1 ATOM 3549 N ND1 . HIS C 1 34 ? -2.085 -9.892 6.457 1.00 24.86 ? 34 HIS C ND1 1 ATOM 3550 C CD2 . HIS C 1 34 ? -2.638 -7.819 6.855 1.00 21.94 ? 34 HIS C CD2 1 ATOM 3551 C CE1 . HIS C 1 34 ? -1.961 -9.232 5.323 1.00 22.28 ? 34 HIS C CE1 1 ATOM 3552 N NE2 . HIS C 1 34 ? -2.291 -7.969 5.539 1.00 26.03 ? 34 HIS C NE2 1 ATOM 3553 N N . TRP C 1 35 ? -3.176 -11.649 11.181 1.00 21.14 ? 35 TRP C N 1 ATOM 3554 C CA . TRP C 1 35 ? -3.422 -11.960 12.577 1.00 21.14 ? 35 TRP C CA 1 ATOM 3555 C C . TRP C 1 35 ? -2.317 -11.423 13.467 1.00 19.46 ? 35 TRP C C 1 ATOM 3556 O O . TRP C 1 35 ? -1.140 -11.450 13.107 1.00 23.16 ? 35 TRP C O 1 ATOM 3557 C CB . TRP C 1 35 ? -3.566 -13.465 12.786 1.00 21.52 ? 35 TRP C CB 1 ATOM 3558 C CG . TRP C 1 35 ? -4.787 -14.070 12.192 1.00 23.91 ? 35 TRP C CG 1 ATOM 3559 C CD1 . TRP C 1 35 ? -4.917 -14.573 10.935 1.00 20.78 ? 35 TRP C CD1 1 ATOM 3560 C CD2 . TRP C 1 35 ? -6.057 -14.267 12.839 1.00 28.02 ? 35 TRP C CD2 1 ATOM 3561 N NE1 . TRP C 1 35 ? -6.185 -15.073 10.756 1.00 28.10 ? 35 TRP C NE1 1 ATOM 3562 C CE2 . TRP C 1 35 ? -6.904 -14.895 11.905 1.00 20.80 ? 35 TRP C CE2 1 ATOM 3563 C CE3 . TRP C 1 35 ? -6.551 -13.981 14.118 1.00 28.24 ? 35 TRP C CE3 1 ATOM 3564 C CZ2 . TRP C 1 35 ? -8.218 -15.232 12.202 1.00 26.60 ? 35 TRP C CZ2 1 ATOM 3565 C CZ3 . TRP C 1 35 ? -7.859 -14.319 14.414 1.00 22.13 ? 35 TRP C CZ3 1 ATOM 3566 C CH2 . TRP C 1 35 ? -8.677 -14.939 13.462 1.00 30.00 ? 35 TRP C CH2 1 ATOM 3567 N N . TYR C 1 36 ? -2.709 -10.960 14.645 1.00 21.40 ? 36 TYR C N 1 ATOM 3568 C CA . TYR C 1 36 ? -1.781 -10.354 15.589 1.00 16.56 ? 36 TYR C CA 1 ATOM 3569 C C . TYR C 1 36 ? -1.951 -10.931 16.975 1.00 16.72 ? 36 TYR C C 1 ATOM 3570 O O . TYR C 1 36 ? -3.005 -11.457 17.326 1.00 16.64 ? 36 TYR C O 1 ATOM 3571 C CB . TYR C 1 36 ? -2.015 -8.849 15.668 1.00 16.97 ? 36 TYR C CB 1 ATOM 3572 C CG . TYR C 1 36 ? -1.730 -8.116 14.388 1.00 20.30 ? 36 TYR C CG 1 ATOM 3573 C CD1 . TYR C 1 36 ? -2.729 -7.927 13.437 1.00 18.72 ? 36 TYR C CD1 1 ATOM 3574 C CD2 . TYR C 1 36 ? -0.458 -7.612 14.124 1.00 16.72 ? 36 TYR C CD2 1 ATOM 3575 C CE1 . TYR C 1 36 ? -2.468 -7.265 12.258 1.00 17.11 ? 36 TYR C CE1 1 ATOM 3576 C CE2 . TYR C 1 36 ? -0.190 -6.943 12.951 1.00 18.93 ? 36 TYR C CE2 1 ATOM 3577 C CZ . TYR C 1 36 ? -1.198 -6.768 12.015 1.00 24.57 ? 36 TYR C CZ 1 ATOM 3578 O OH . TYR C 1 36 ? -0.936 -6.088 10.834 1.00 20.19 ? 36 TYR C OH 1 ATOM 3579 N N . GLN C 1 37 ? -0.903 -10.814 17.775 1.00 19.53 ? 37 GLN C N 1 ATOM 3580 C CA . GLN C 1 37 ? -0.964 -11.239 19.158 1.00 21.20 ? 37 GLN C CA 1 ATOM 3581 C C . GLN C 1 37 ? -0.678 -10.041 20.046 1.00 20.97 ? 37 GLN C C 1 ATOM 3582 O O . GLN C 1 37 ? 0.240 -9.283 19.782 1.00 26.36 ? 37 GLN C O 1 ATOM 3583 C CB . GLN C 1 37 ? 0.062 -12.332 19.420 1.00 19.40 ? 37 GLN C CB 1 ATOM 3584 C CG . GLN C 1 37 ? 0.155 -12.752 20.878 1.00 18.43 ? 37 GLN C CG 1 ATOM 3585 C CD . GLN C 1 37 ? 1.336 -13.661 21.130 1.00 26.75 ? 37 GLN C CD 1 ATOM 3586 O OE1 . GLN C 1 37 ? 2.479 -13.210 21.144 1.00 23.66 ? 37 GLN C OE1 1 ATOM 3587 N NE2 . GLN C 1 37 ? 1.071 -14.954 21.307 1.00 21.29 ? 37 GLN C NE2 1 ATOM 3588 N N . GLN C 1 38 ? -1.470 -9.842 21.090 1.00 22.12 ? 38 GLN C N 1 ATOM 3589 C CA . GLN C 1 38 ? -1.107 -8.814 22.059 1.00 24.96 ? 38 GLN C CA 1 ATOM 3590 C C . GLN C 1 38 ? -1.010 -9.383 23.456 1.00 21.77 ? 38 GLN C C 1 ATOM 3591 O O . GLN C 1 38 ? -2.020 -9.676 24.088 1.00 20.99 ? 38 GLN C O 1 ATOM 3592 C CB . GLN C 1 38 ? -2.044 -7.608 22.026 1.00 20.99 ? 38 GLN C CB 1 ATOM 3593 C CG . GLN C 1 38 ? -1.507 -6.446 22.848 1.00 17.25 ? 38 GLN C CG 1 ATOM 3594 C CD . GLN C 1 38 ? -2.235 -5.156 22.573 1.00 22.62 ? 38 GLN C CD 1 ATOM 3595 O OE1 . GLN C 1 38 ? -3.459 -5.139 22.435 1.00 20.85 ? 38 GLN C OE1 1 ATOM 3596 N NE2 . GLN C 1 38 ? -1.489 -4.066 22.481 1.00 22.05 ? 38 GLN C NE2 1 ATOM 3597 N N . ARG C 1 39 ? 0.229 -9.553 23.905 1.00 18.39 ? 39 ARG C N 1 ATOM 3598 C CA . ARG C 1 39 ? 0.536 -9.974 25.256 1.00 18.63 ? 39 ARG C CA 1 ATOM 3599 C C . ARG C 1 39 ? 0.456 -8.779 26.185 1.00 21.98 ? 39 ARG C C 1 ATOM 3600 O O . ARG C 1 39 ? 0.538 -7.637 25.736 1.00 22.65 ? 39 ARG C O 1 ATOM 3601 C CB . ARG C 1 39 ? 1.949 -10.535 25.311 1.00 21.18 ? 39 ARG C CB 1 ATOM 3602 C CG . ARG C 1 39 ? 2.119 -11.890 24.683 1.00 22.79 ? 39 ARG C CG 1 ATOM 3603 C CD . ARG C 1 39 ? 3.573 -12.243 24.641 1.00 20.16 ? 39 ARG C CD 1 ATOM 3604 N NE . ARG C 1 39 ? 3.777 -13.583 24.116 1.00 37.74 ? 39 ARG C NE 1 ATOM 3605 C CZ . ARG C 1 39 ? 4.961 -14.070 23.759 1.00 47.83 ? 39 ARG C CZ 1 ATOM 3606 N NH1 . ARG C 1 39 ? 6.045 -13.315 23.873 1.00 36.91 ? 39 ARG C NH1 1 ATOM 3607 N NH2 . ARG C 1 39 ? 5.056 -15.307 23.285 1.00 55.59 ? 39 ARG C NH2 1 ATOM 3608 N N . THR C 1 40 ? 0.324 -9.052 27.480 1.00 22.38 ? 40 THR C N 1 ATOM 3609 C CA . THR C 1 40 ? 0.192 -8.008 28.494 1.00 23.25 ? 40 THR C CA 1 ATOM 3610 C C . THR C 1 40 ? 1.296 -6.933 28.431 1.00 23.90 ? 40 THR C C 1 ATOM 3611 O O . THR C 1 40 ? 2.483 -7.242 28.359 1.00 18.72 ? 40 THR C O 1 ATOM 3612 C CB . THR C 1 40 ? 0.123 -8.634 29.908 1.00 31.87 ? 40 THR C CB 1 ATOM 3613 O OG1 . THR C 1 40 ? -0.992 -9.539 29.988 1.00 21.68 ? 40 THR C OG1 1 ATOM 3614 C CG2 . THR C 1 40 ? -0.002 -7.549 30.973 1.00 20.03 ? 40 THR C CG2 1 ATOM 3615 N N . ASN C 1 41 ? 0.879 -5.668 28.450 1.00 21.32 ? 41 ASN C N 1 ATOM 3616 C CA . ASN C 1 41 ? 1.778 -4.515 28.291 1.00 24.04 ? 41 ASN C CA 1 ATOM 3617 C C . ASN C 1 41 ? 2.505 -4.418 26.944 1.00 34.17 ? 41 ASN C C 1 ATOM 3618 O O . ASN C 1 41 ? 3.201 -3.432 26.694 1.00 30.87 ? 41 ASN C O 1 ATOM 3619 C CB . ASN C 1 41 ? 2.793 -4.403 29.434 1.00 20.22 ? 41 ASN C CB 1 ATOM 3620 C CG . ASN C 1 41 ? 2.134 -4.298 30.796 1.00 30.56 ? 41 ASN C CG 1 ATOM 3621 O OD1 . ASN C 1 41 ? 2.368 -5.134 31.662 1.00 26.42 ? 41 ASN C OD1 1 ATOM 3622 N ND2 . ASN C 1 41 ? 1.302 -3.276 30.989 1.00 28.44 ? 41 ASN C ND2 1 ATOM 3623 N N . GLY C 1 42 ? 2.329 -5.410 26.073 1.00 18.22 ? 42 GLY C N 1 ATOM 3624 C CA . GLY C 1 42 ? 3.022 -5.412 24.796 1.00 29.55 ? 42 GLY C CA 1 ATOM 3625 C C . GLY C 1 42 ? 2.362 -4.666 23.642 1.00 20.61 ? 42 GLY C C 1 ATOM 3626 O O . GLY C 1 42 ? 1.237 -4.188 23.748 1.00 18.53 ? 42 GLY C O 1 ATOM 3627 N N . SER C 1 43 ? 3.089 -4.566 22.533 1.00 19.79 ? 43 SER C N 1 ATOM 3628 C CA . SER C 1 43 ? 2.526 -4.070 21.284 1.00 20.03 ? 43 SER C CA 1 ATOM 3629 C C . SER C 1 43 ? 2.051 -5.292 20.521 1.00 16.37 ? 43 SER C C 1 ATOM 3630 O O . SER C 1 43 ? 2.480 -6.394 20.815 1.00 18.05 ? 43 SER C O 1 ATOM 3631 C CB . SER C 1 43 ? 3.576 -3.299 20.487 1.00 17.24 ? 43 SER C CB 1 ATOM 3632 O OG . SER C 1 43 ? 3.928 -2.090 21.137 1.00 23.61 ? 43 SER C OG 1 ATOM 3633 N N . PRO C 1 44 ? 1.146 -5.113 19.554 1.00 19.86 ? 44 PRO C N 1 ATOM 3634 C CA . PRO C 1 44 ? 0.752 -6.270 18.740 1.00 22.77 ? 44 PRO C CA 1 ATOM 3635 C C . PRO C 1 44 ? 1.953 -6.914 18.021 1.00 19.73 ? 44 PRO C C 1 ATOM 3636 O O . PRO C 1 44 ? 2.848 -6.213 17.558 1.00 22.26 ? 44 PRO C O 1 ATOM 3637 C CB . PRO C 1 44 ? -0.222 -5.666 17.725 1.00 20.48 ? 44 PRO C CB 1 ATOM 3638 C CG . PRO C 1 44 ? -0.753 -4.425 18.401 1.00 21.58 ? 44 PRO C CG 1 ATOM 3639 C CD . PRO C 1 44 ? 0.385 -3.897 19.216 1.00 21.63 ? 44 PRO C CD 1 ATOM 3640 N N . ARG C 1 45 ? 1.979 -8.239 17.969 1.00 17.26 ? 45 ARG C N 1 ATOM 3641 C CA . ARG C 1 45 ? 2.974 -8.970 17.201 1.00 21.39 ? 45 ARG C CA 1 ATOM 3642 C C . ARG C 1 45 ? 2.271 -9.676 16.052 1.00 20.20 ? 45 ARG C C 1 ATOM 3643 O O . ARG C 1 45 ? 1.403 -10.527 16.269 1.00 23.21 ? 45 ARG C O 1 ATOM 3644 C CB . ARG C 1 45 ? 3.729 -9.979 18.086 1.00 21.33 ? 45 ARG C CB 1 ATOM 3645 C CG . ARG C 1 45 ? 4.537 -11.014 17.313 1.00 28.03 ? 45 ARG C CG 1 ATOM 3646 C CD . ARG C 1 45 ? 5.609 -11.742 18.149 1.00 28.02 ? 45 ARG C CD 1 ATOM 3647 N NE . ARG C 1 45 ? 5.115 -12.834 18.999 1.00 40.41 ? 45 ARG C NE 1 ATOM 3648 C CZ . ARG C 1 45 ? 5.731 -14.010 19.157 1.00 38.48 ? 45 ARG C CZ 1 ATOM 3649 N NH1 . ARG C 1 45 ? 6.859 -14.270 18.499 1.00 40.85 ? 45 ARG C NH1 1 ATOM 3650 N NH2 . ARG C 1 45 ? 5.223 -14.937 19.969 1.00 33.61 ? 45 ARG C NH2 1 ATOM 3651 N N . LEU C 1 46 ? 2.626 -9.298 14.829 1.00 18.97 ? 46 LEU C N 1 ATOM 3652 C CA . LEU C 1 46 ? 2.156 -9.980 13.625 1.00 20.11 ? 46 LEU C CA 1 ATOM 3653 C C . LEU C 1 46 ? 2.502 -11.476 13.664 1.00 23.25 ? 46 LEU C C 1 ATOM 3654 O O . LEU C 1 46 ? 3.652 -11.852 13.928 1.00 24.08 ? 46 LEU C O 1 ATOM 3655 C CB . LEU C 1 46 ? 2.799 -9.339 12.396 1.00 22.14 ? 46 LEU C CB 1 ATOM 3656 C CG . LEU C 1 46 ? 2.558 -9.966 11.026 1.00 19.93 ? 46 LEU C CG 1 ATOM 3657 C CD1 . LEU C 1 46 ? 1.200 -9.540 10.479 1.00 17.17 ? 46 LEU C CD1 1 ATOM 3658 C CD2 . LEU C 1 46 ? 3.689 -9.570 10.085 1.00 22.74 ? 46 LEU C CD2 1 ATOM 3659 N N . LEU C 1 47 ? 1.507 -12.321 13.393 1.00 22.65 ? 47 LEU C N 1 ATOM 3660 C CA . LEU C 1 47 ? 1.660 -13.778 13.502 1.00 23.60 ? 47 LEU C CA 1 ATOM 3661 C C . LEU C 1 47 ? 1.530 -14.506 12.176 1.00 27.04 ? 47 LEU C C 1 ATOM 3662 O O . LEU C 1 47 ? 2.262 -15.454 11.898 1.00 33.02 ? 47 LEU C O 1 ATOM 3663 C CB . LEU C 1 47 ? 0.569 -14.340 14.399 1.00 22.69 ? 47 LEU C CB 1 ATOM 3664 C CG . LEU C 1 47 ? 0.611 -14.039 15.877 1.00 22.32 ? 47 LEU C CG 1 ATOM 3665 C CD1 . LEU C 1 47 ? -0.737 -14.433 16.465 1.00 24.39 ? 47 LEU C CD1 1 ATOM 3666 C CD2 . LEU C 1 47 ? 1.735 -14.844 16.491 1.00 26.58 ? 47 LEU C CD2 1 ATOM 3667 N N . ILE C 1 48 ? 0.550 -14.077 11.388 1.00 22.52 ? 48 ILE C N 1 ATOM 3668 C CA . ILE C 1 48 ? 0.204 -14.699 10.124 1.00 16.80 ? 48 ILE C CA 1 ATOM 3669 C C . ILE C 1 48 ? -0.143 -13.577 9.150 1.00 23.13 ? 48 ILE C C 1 ATOM 3670 O O . ILE C 1 48 ? -0.796 -12.604 9.526 1.00 25.70 ? 48 ILE C O 1 ATOM 3671 C CB . ILE C 1 48 ? -1.034 -15.624 10.288 1.00 17.41 ? 48 ILE C CB 1 ATOM 3672 C CG1 . ILE C 1 48 ? -0.707 -16.849 11.153 1.00 23.28 ? 48 ILE C CG1 1 ATOM 3673 C CG2 . ILE C 1 48 ? -1.581 -16.063 8.950 1.00 19.00 ? 48 ILE C CG2 1 ATOM 3674 C CD1 . ILE C 1 48 ? 0.379 -17.726 10.594 1.00 20.60 ? 48 ILE C CD1 1 ATOM 3675 N N . LYS C 1 49 ? 0.297 -13.688 7.902 1.00 23.35 ? 49 LYS C N 1 ATOM 3676 C CA . LYS C 1 49 ? -0.118 -12.719 6.897 1.00 23.22 ? 49 LYS C CA 1 ATOM 3677 C C . LYS C 1 49 ? -0.878 -13.387 5.749 1.00 25.66 ? 49 LYS C C 1 ATOM 3678 O O . LYS C 1 49 ? -0.601 -14.530 5.388 1.00 26.85 ? 49 LYS C O 1 ATOM 3679 C CB . LYS C 1 49 ? 1.072 -11.911 6.382 1.00 22.29 ? 49 LYS C CB 1 ATOM 3680 C CG . LYS C 1 49 ? 2.049 -12.679 5.512 1.00 20.40 ? 49 LYS C CG 1 ATOM 3681 C CD . LYS C 1 49 ? 3.291 -11.833 5.215 1.00 15.53 ? 49 LYS C CD 1 ATOM 3682 C CE . LYS C 1 49 ? 4.387 -12.653 4.534 1.00 20.79 ? 49 LYS C CE 1 ATOM 3683 N NZ . LYS C 1 49 ? 4.099 -12.913 3.075 1.00 19.26 ? 49 LYS C NZ 1 ATOM 3684 N N . TYR C 1 50 ? -1.851 -12.666 5.198 1.00 24.62 ? 50 TYR C N 1 ATOM 3685 C CA . TYR C 1 50 ? -2.633 -13.141 4.058 1.00 25.01 ? 50 TYR C CA 1 ATOM 3686 C C . TYR C 1 50 ? -3.273 -14.509 4.294 1.00 27.29 ? 50 TYR C C 1 ATOM 3687 O O . TYR C 1 50 ? -3.069 -15.441 3.516 1.00 34.14 ? 50 TYR C O 1 ATOM 3688 C CB . TYR C 1 50 ? -1.794 -13.121 2.769 1.00 23.83 ? 50 TYR C CB 1 ATOM 3689 C CG . TYR C 1 50 ? -1.536 -11.717 2.282 1.00 29.25 ? 50 TYR C CG 1 ATOM 3690 C CD1 . TYR C 1 50 ? -0.263 -11.140 2.383 1.00 24.47 ? 50 TYR C CD1 1 ATOM 3691 C CD2 . TYR C 1 50 ? -2.577 -10.940 1.753 1.00 22.72 ? 50 TYR C CD2 1 ATOM 3692 C CE1 . TYR C 1 50 ? -0.027 -9.829 1.940 1.00 21.13 ? 50 TYR C CE1 1 ATOM 3693 C CE2 . TYR C 1 50 ? -2.353 -9.626 1.323 1.00 24.00 ? 50 TYR C CE2 1 ATOM 3694 C CZ . TYR C 1 50 ? -1.076 -9.085 1.420 1.00 30.30 ? 50 TYR C CZ 1 ATOM 3695 O OH . TYR C 1 50 ? -0.848 -7.797 0.998 1.00 30.48 ? 50 TYR C OH 1 ATOM 3696 N N . ALA C 1 51 ? -4.040 -14.601 5.378 1.00 21.95 ? 51 ALA C N 1 ATOM 3697 C CA . ALA C 1 51 ? -4.764 -15.810 5.762 1.00 23.58 ? 51 ALA C CA 1 ATOM 3698 C C . ALA C 1 51 ? -3.899 -16.921 6.330 1.00 25.43 ? 51 ALA C C 1 ATOM 3699 O O . ALA C 1 51 ? -4.188 -17.421 7.423 1.00 24.38 ? 51 ALA C O 1 ATOM 3700 C CB . ALA C 1 51 ? -5.638 -16.345 4.606 1.00 22.68 ? 51 ALA C CB 1 ATOM 3701 N N . SER C 1 52 ? -2.836 -17.286 5.610 1.00 19.70 ? 52 SER C N 1 ATOM 3702 C CA . SER C 1 52 ? -2.133 -18.536 5.887 1.00 24.71 ? 52 SER C CA 1 ATOM 3703 C C . SER C 1 52 ? -0.612 -18.492 5.841 1.00 26.56 ? 52 SER C C 1 ATOM 3704 O O . SER C 1 52 ? 0.030 -19.506 6.101 1.00 27.81 ? 52 SER C O 1 ATOM 3705 C CB . SER C 1 52 ? -2.582 -19.605 4.900 1.00 19.55 ? 52 SER C CB 1 ATOM 3706 O OG . SER C 1 52 ? -1.886 -19.453 3.675 1.00 26.73 ? 52 SER C OG 1 ATOM 3707 N N . GLU C 1 53 ? -0.026 -17.352 5.496 1.00 24.67 ? 53 GLU C N 1 ATOM 3708 C CA . GLU C 1 53 ? 1.418 -17.312 5.252 1.00 21.34 ? 53 GLU C CA 1 ATOM 3709 C C . GLU C 1 53 ? 2.183 -16.974 6.510 1.00 22.35 ? 53 GLU C C 1 ATOM 3710 O O . GLU C 1 53 ? 1.796 -16.082 7.241 1.00 25.49 ? 53 GLU C O 1 ATOM 3711 C CB . GLU C 1 53 ? 1.762 -16.292 4.171 1.00 28.68 ? 53 GLU C CB 1 ATOM 3712 C CG . GLU C 1 53 ? 1.047 -16.499 2.848 1.00 28.34 ? 53 GLU C CG 1 ATOM 3713 C CD . GLU C 1 53 ? 1.325 -15.370 1.889 1.00 29.48 ? 53 GLU C CD 1 ATOM 3714 O OE1 . GLU C 1 53 ? 1.912 -14.358 2.329 1.00 27.95 ? 53 GLU C OE1 1 ATOM 3715 O OE2 . GLU C 1 53 ? 0.958 -15.479 0.703 1.00 35.00 ? 53 GLU C OE2 1 ATOM 3716 N N . SER C 1 54 ? 3.287 -17.669 6.752 1.00 27.51 ? 54 SER C N 1 ATOM 3717 C CA . SER C 1 54 ? 4.024 -17.498 7.998 1.00 30.84 ? 54 SER C CA 1 ATOM 3718 C C . SER C 1 54 ? 4.891 -16.243 8.048 1.00 31.69 ? 54 SER C C 1 ATOM 3719 O O . SER C 1 54 ? 5.159 -15.607 7.025 1.00 34.91 ? 54 SER C O 1 ATOM 3720 C CB . SER C 1 54 ? 4.882 -18.727 8.291 1.00 30.92 ? 54 SER C CB 1 ATOM 3721 O OG . SER C 1 54 ? 5.833 -18.914 7.270 1.00 42.08 ? 54 SER C OG 1 ATOM 3722 N N . ILE C 1 55 ? 5.327 -15.916 9.262 1.00 30.45 ? 55 ILE C N 1 ATOM 3723 C CA . ILE C 1 55 ? 6.144 -14.745 9.544 1.00 28.80 ? 55 ILE C CA 1 ATOM 3724 C C . ILE C 1 55 ? 7.438 -15.176 10.219 1.00 31.37 ? 55 ILE C C 1 ATOM 3725 O O . ILE C 1 55 ? 7.420 -16.004 11.131 1.00 32.44 ? 55 ILE C O 1 ATOM 3726 C CB . ILE C 1 55 ? 5.415 -13.785 10.495 1.00 23.13 ? 55 ILE C CB 1 ATOM 3727 C CG1 . ILE C 1 55 ? 4.033 -13.445 9.945 1.00 16.89 ? 55 ILE C CG1 1 ATOM 3728 C CG2 . ILE C 1 55 ? 6.253 -12.535 10.734 1.00 24.06 ? 55 ILE C CG2 1 ATOM 3729 C CD1 . ILE C 1 55 ? 4.084 -12.838 8.557 1.00 21.96 ? 55 ILE C CD1 1 ATOM 3730 N N . SER C 1 56 ? 8.562 -14.622 9.777 1.00 32.67 ? 56 SER C N 1 ATOM 3731 C CA . SER C 1 56 ? 9.851 -14.990 10.356 1.00 37.46 ? 56 SER C CA 1 ATOM 3732 C C . SER C 1 56 ? 9.927 -14.692 11.849 1.00 41.39 ? 56 SER C C 1 ATOM 3733 O O . SER C 1 56 ? 9.818 -13.541 12.274 1.00 36.89 ? 56 SER C O 1 ATOM 3734 C CB . SER C 1 56 ? 11.000 -14.279 9.648 1.00 44.70 ? 56 SER C CB 1 ATOM 3735 O OG . SER C 1 56 ? 12.188 -14.398 10.415 1.00 48.62 ? 56 SER C OG 1 ATOM 3736 N N . GLY C 1 57 ? 10.118 -15.745 12.637 1.00 40.13 ? 57 GLY C N 1 ATOM 3737 C CA . GLY C 1 57 ? 10.284 -15.612 14.069 1.00 32.11 ? 57 GLY C CA 1 ATOM 3738 C C . GLY C 1 57 ? 9.118 -16.160 14.861 1.00 35.58 ? 57 GLY C C 1 ATOM 3739 O O . GLY C 1 57 ? 9.199 -16.272 16.086 1.00 29.47 ? 57 GLY C O 1 ATOM 3740 N N . ILE C 1 58 ? 8.032 -16.495 14.167 1.00 38.16 ? 58 ILE C N 1 ATOM 3741 C CA . ILE C 1 58 ? 6.815 -16.963 14.830 1.00 33.54 ? 58 ILE C CA 1 ATOM 3742 C C . ILE C 1 58 ? 6.810 -18.486 14.888 1.00 33.82 ? 58 ILE C C 1 ATOM 3743 O O . ILE C 1 58 ? 6.925 -19.147 13.851 1.00 39.03 ? 58 ILE C O 1 ATOM 3744 C CB . ILE C 1 58 ? 5.533 -16.467 14.113 1.00 28.25 ? 58 ILE C CB 1 ATOM 3745 C CG1 . ILE C 1 58 ? 5.517 -14.935 14.004 1.00 28.40 ? 58 ILE C CG1 1 ATOM 3746 C CG2 . ILE C 1 58 ? 4.290 -17.008 14.799 1.00 20.06 ? 58 ILE C CG2 1 ATOM 3747 C CD1 . ILE C 1 58 ? 5.607 -14.213 15.323 1.00 27.00 ? 58 ILE C CD1 1 ATOM 3748 N N . PRO C 1 59 ? 6.695 -19.049 16.105 1.00 34.64 ? 59 PRO C N 1 ATOM 3749 C CA . PRO C 1 59 ? 6.736 -20.511 16.269 1.00 35.00 ? 59 PRO C CA 1 ATOM 3750 C C . PRO C 1 59 ? 5.731 -21.232 15.364 1.00 33.44 ? 59 PRO C C 1 ATOM 3751 O O . PRO C 1 59 ? 4.614 -20.758 15.153 1.00 33.06 ? 59 PRO C O 1 ATOM 3752 C CB . PRO C 1 59 ? 6.422 -20.728 17.768 1.00 28.47 ? 59 PRO C CB 1 ATOM 3753 C CG . PRO C 1 59 ? 5.977 -19.393 18.301 1.00 36.24 ? 59 PRO C CG 1 ATOM 3754 C CD . PRO C 1 59 ? 6.569 -18.342 17.392 1.00 30.32 ? 59 PRO C CD 1 ATOM 3755 N N . SER C 1 60 ? 6.151 -22.375 14.839 1.00 35.32 ? 60 SER C N 1 ATOM 3756 C CA . SER C 1 60 ? 5.413 -23.095 13.813 1.00 32.15 ? 60 SER C CA 1 ATOM 3757 C C . SER C 1 60 ? 4.055 -23.585 14.286 1.00 31.36 ? 60 SER C C 1 ATOM 3758 O O . SER C 1 60 ? 3.225 -23.991 13.472 1.00 33.10 ? 60 SER C O 1 ATOM 3759 C CB . SER C 1 60 ? 6.231 -24.285 13.306 1.00 34.65 ? 60 SER C CB 1 ATOM 3760 O OG . SER C 1 60 ? 6.433 -25.240 14.341 1.00 43.55 ? 60 SER C OG 1 ATOM 3761 N N . ARG C 1 61 ? 3.817 -23.546 15.594 1.00 31.58 ? 61 ARG C N 1 ATOM 3762 C CA . ARG C 1 61 ? 2.532 -24.010 16.117 1.00 35.04 ? 61 ARG C CA 1 ATOM 3763 C C . ARG C 1 61 ? 1.395 -23.049 15.759 1.00 35.16 ? 61 ARG C C 1 ATOM 3764 O O . ARG C 1 61 ? 0.227 -23.408 15.845 1.00 39.51 ? 61 ARG C O 1 ATOM 3765 C CB . ARG C 1 61 ? 2.594 -24.253 17.625 1.00 33.28 ? 61 ARG C CB 1 ATOM 3766 C CG . ARG C 1 61 ? 2.801 -23.005 18.449 1.00 39.26 ? 61 ARG C CG 1 ATOM 3767 C CD . ARG C 1 61 ? 2.675 -23.308 19.932 1.00 35.85 ? 61 ARG C CD 1 ATOM 3768 N NE . ARG C 1 61 ? 2.902 -22.112 20.716 1.00 34.46 ? 61 ARG C NE 1 ATOM 3769 C CZ . ARG C 1 61 ? 4.107 -21.663 21.041 1.00 42.45 ? 61 ARG C CZ 1 ATOM 3770 N NH1 . ARG C 1 61 ? 5.184 -22.334 20.656 1.00 37.97 ? 61 ARG C NH1 1 ATOM 3771 N NH2 . ARG C 1 61 ? 4.233 -20.547 21.751 1.00 40.58 ? 61 ARG C NH2 1 ATOM 3772 N N . PHE C 1 62 ? 1.753 -21.833 15.356 1.00 30.87 ? 62 PHE C N 1 ATOM 3773 C CA . PHE C 1 62 ? 0.793 -20.886 14.800 1.00 26.20 ? 62 PHE C CA 1 ATOM 3774 C C . PHE C 1 62 ? 0.596 -21.165 13.306 1.00 29.92 ? 62 PHE C C 1 ATOM 3775 O O . PHE C 1 62 ? 1.571 -21.289 12.550 1.00 26.24 ? 62 PHE C O 1 ATOM 3776 C CB . PHE C 1 62 ? 1.276 -19.452 15.005 1.00 21.70 ? 62 PHE C CB 1 ATOM 3777 C CG . PHE C 1 62 ? 1.267 -18.999 16.455 1.00 30.89 ? 62 PHE C CG 1 ATOM 3778 C CD1 . PHE C 1 62 ? 2.431 -19.016 17.225 1.00 35.41 ? 62 PHE C CD1 1 ATOM 3779 C CD2 . PHE C 1 62 ? 0.096 -18.543 17.039 1.00 26.35 ? 62 PHE C CD2 1 ATOM 3780 C CE1 . PHE C 1 62 ? 2.420 -18.597 18.555 1.00 30.68 ? 62 PHE C CE1 1 ATOM 3781 C CE2 . PHE C 1 62 ? 0.075 -18.125 18.359 1.00 39.17 ? 62 PHE C CE2 1 ATOM 3782 C CZ . PHE C 1 62 ? 1.245 -18.153 19.125 1.00 33.06 ? 62 PHE C CZ 1 ATOM 3783 N N . SER C 1 63 ? -0.659 -21.273 12.886 1.00 23.81 ? 63 SER C N 1 ATOM 3784 C CA . SER C 1 63 ? -0.981 -21.353 11.465 1.00 26.15 ? 63 SER C CA 1 ATOM 3785 C C . SER C 1 63 ? -2.337 -20.681 11.239 1.00 32.48 ? 63 SER C C 1 ATOM 3786 O O . SER C 1 63 ? -3.034 -20.332 12.204 1.00 25.46 ? 63 SER C O 1 ATOM 3787 C CB . SER C 1 63 ? -1.012 -22.826 10.976 1.00 28.57 ? 63 SER C CB 1 ATOM 3788 O OG . SER C 1 63 ? -2.245 -23.476 11.275 1.00 25.07 ? 63 SER C OG 1 ATOM 3789 N N . GLY C 1 64 ? -2.704 -20.511 9.971 1.00 22.74 ? 64 GLY C N 1 ATOM 3790 C CA . GLY C 1 64 ? -3.934 -19.822 9.627 1.00 25.39 ? 64 GLY C CA 1 ATOM 3791 C C . GLY C 1 64 ? -4.558 -20.329 8.344 1.00 27.92 ? 64 GLY C C 1 ATOM 3792 O O . GLY C 1 64 ? -3.877 -20.876 7.485 1.00 29.22 ? 64 GLY C O 1 ATOM 3793 N N . SER C 1 65 ? -5.862 -20.150 8.207 1.00 24.45 ? 65 SER C N 1 ATOM 3794 C CA . SER C 1 65 ? -6.570 -20.704 7.062 1.00 24.25 ? 65 SER C CA 1 ATOM 3795 C C . SER C 1 65 ? -7.845 -19.931 6.750 1.00 20.96 ? 65 SER C C 1 ATOM 3796 O O . SER C 1 65 ? -8.303 -19.109 7.538 1.00 24.57 ? 65 SER C O 1 ATOM 3797 C CB . SER C 1 65 ? -6.908 -22.175 7.311 1.00 25.08 ? 65 SER C CB 1 ATOM 3798 O OG . SER C 1 65 ? -7.903 -22.277 8.324 1.00 34.39 ? 65 SER C OG 1 ATOM 3799 N N . GLY C 1 66 ? -8.413 -20.210 5.586 1.00 24.22 ? 66 GLY C N 1 ATOM 3800 C CA . GLY C 1 66 ? -9.657 -19.594 5.188 1.00 23.95 ? 66 GLY C CA 1 ATOM 3801 C C . GLY C 1 66 ? -9.538 -18.667 4.000 1.00 26.42 ? 66 GLY C C 1 ATOM 3802 O O . GLY C 1 66 ? -8.445 -18.210 3.647 1.00 28.28 ? 66 GLY C O 1 ATOM 3803 N N . SER C 1 67 ? -10.678 -18.402 3.373 1.00 28.60 ? 67 SER C N 1 ATOM 3804 C CA . SER C 1 67 ? -10.763 -17.442 2.279 1.00 28.59 ? 67 SER C CA 1 ATOM 3805 C C . SER C 1 67 ? -12.209 -17.031 2.116 1.00 32.91 ? 67 SER C C 1 ATOM 3806 O O . SER C 1 67 ? -13.119 -17.751 2.542 1.00 37.13 ? 67 SER C O 1 ATOM 3807 C CB . SER C 1 67 ? -10.267 -18.043 0.975 1.00 23.67 ? 67 SER C CB 1 ATOM 3808 O OG . SER C 1 67 ? -11.124 -19.084 0.566 1.00 47.72 ? 67 SER C OG 1 ATOM 3809 N N . GLY C 1 68 ? -12.425 -15.873 1.505 1.00 27.92 ? 68 GLY C N 1 ATOM 3810 C CA . GLY C 1 68 ? -13.769 -15.359 1.342 1.00 22.41 ? 68 GLY C CA 1 ATOM 3811 C C . GLY C 1 68 ? -14.172 -14.566 2.558 1.00 32.72 ? 68 GLY C C 1 ATOM 3812 O O . GLY C 1 68 ? -13.820 -13.387 2.670 1.00 33.67 ? 68 GLY C O 1 ATOM 3813 N N . THR C 1 69 ? -14.889 -15.207 3.481 1.00 27.35 ? 69 THR C N 1 ATOM 3814 C CA . THR C 1 69 ? -15.404 -14.508 4.661 1.00 32.27 ? 69 THR C CA 1 ATOM 3815 C C . THR C 1 69 ? -15.031 -15.164 5.983 1.00 29.68 ? 69 THR C C 1 ATOM 3816 O O . THR C 1 69 ? -14.990 -14.493 7.003 1.00 34.25 ? 69 THR C O 1 ATOM 3817 C CB . THR C 1 69 ? -16.949 -14.340 4.621 1.00 37.69 ? 69 THR C CB 1 ATOM 3818 O OG1 . THR C 1 69 ? -17.584 -15.600 4.873 1.00 37.21 ? 69 THR C OG1 1 ATOM 3819 C CG2 . THR C 1 69 ? -17.398 -13.794 3.278 1.00 30.19 ? 69 THR C CG2 1 ATOM 3820 N N . ASP C 1 70 ? -14.776 -16.469 5.967 1.00 31.33 ? 70 ASP C N 1 ATOM 3821 C CA . ASP C 1 70 ? -14.471 -17.200 7.195 1.00 28.39 ? 70 ASP C CA 1 ATOM 3822 C C . ASP C 1 70 ? -12.987 -17.502 7.360 1.00 28.48 ? 70 ASP C C 1 ATOM 3823 O O . ASP C 1 70 ? -12.388 -18.194 6.534 1.00 26.08 ? 70 ASP C O 1 ATOM 3824 C CB . ASP C 1 70 ? -15.276 -18.502 7.270 1.00 31.07 ? 70 ASP C CB 1 ATOM 3825 C CG . ASP C 1 70 ? -16.780 -18.267 7.277 1.00 37.82 ? 70 ASP C CG 1 ATOM 3826 O OD1 . ASP C 1 70 ? -17.228 -17.161 7.654 1.00 34.21 ? 70 ASP C OD1 1 ATOM 3827 O OD2 . ASP C 1 70 ? -17.514 -19.205 6.896 1.00 41.92 ? 70 ASP C OD2 1 ATOM 3828 N N . PHE C 1 71 ? -12.391 -16.988 8.433 1.00 26.57 ? 71 PHE C N 1 ATOM 3829 C CA . PHE C 1 71 ? -10.954 -17.169 8.633 1.00 26.72 ? 71 PHE C CA 1 ATOM 3830 C C . PHE C 1 71 ? -10.666 -17.771 10.007 1.00 28.89 ? 71 PHE C C 1 ATOM 3831 O O . PHE C 1 71 ? -11.447 -17.611 10.953 1.00 27.71 ? 71 PHE C O 1 ATOM 3832 C CB . PHE C 1 71 ? -10.179 -15.857 8.387 1.00 18.90 ? 71 PHE C CB 1 ATOM 3833 C CG . PHE C 1 71 ? -10.467 -15.227 7.044 1.00 24.57 ? 71 PHE C CG 1 ATOM 3834 C CD1 . PHE C 1 71 ? -9.629 -15.447 5.961 1.00 25.05 ? 71 PHE C CD1 1 ATOM 3835 C CD2 . PHE C 1 71 ? -11.597 -14.440 6.855 1.00 28.62 ? 71 PHE C CD2 1 ATOM 3836 C CE1 . PHE C 1 71 ? -9.896 -14.877 4.725 1.00 23.43 ? 71 PHE C CE1 1 ATOM 3837 C CE2 . PHE C 1 71 ? -11.877 -13.876 5.616 1.00 25.78 ? 71 PHE C CE2 1 ATOM 3838 C CZ . PHE C 1 71 ? -11.024 -14.093 4.555 1.00 24.43 ? 71 PHE C CZ 1 ATOM 3839 N N . THR C 1 72 ? -9.551 -18.485 10.099 1.00 22.89 ? 72 THR C N 1 ATOM 3840 C CA . THR C 1 72 ? -9.218 -19.216 11.307 1.00 27.08 ? 72 THR C CA 1 ATOM 3841 C C . THR C 1 72 ? -7.754 -19.008 11.675 1.00 28.45 ? 72 THR C C 1 ATOM 3842 O O . THR C 1 72 ? -6.866 -19.114 10.826 1.00 29.19 ? 72 THR C O 1 ATOM 3843 C CB . THR C 1 72 ? -9.480 -20.729 11.113 1.00 26.61 ? 72 THR C CB 1 ATOM 3844 O OG1 . THR C 1 72 ? -10.861 -20.937 10.807 1.00 25.86 ? 72 THR C OG1 1 ATOM 3845 C CG2 . THR C 1 72 ? -9.117 -21.515 12.371 1.00 27.02 ? 72 THR C CG2 1 ATOM 3846 N N . LEU C 1 73 ? -7.499 -18.699 12.939 1.00 29.90 ? 73 LEU C N 1 ATOM 3847 C CA . LEU C 1 73 ? -6.132 -18.716 13.446 1.00 30.22 ? 73 LEU C CA 1 ATOM 3848 C C . LEU C 1 73 ? -5.997 -19.955 14.323 1.00 30.94 ? 73 LEU C C 1 ATOM 3849 O O . LEU C 1 73 ? -6.889 -20.247 15.130 1.00 26.84 ? 73 LEU C O 1 ATOM 3850 C CB . LEU C 1 73 ? -5.812 -17.455 14.245 1.00 25.50 ? 73 LEU C CB 1 ATOM 3851 C CG . LEU C 1 73 ? -4.424 -17.462 14.892 1.00 29.71 ? 73 LEU C CG 1 ATOM 3852 C CD1 . LEU C 1 73 ? -3.340 -17.257 13.837 1.00 29.63 ? 73 LEU C CD1 1 ATOM 3853 C CD2 . LEU C 1 73 ? -4.302 -16.441 16.020 1.00 22.70 ? 73 LEU C CD2 1 ATOM 3854 N N . SER C 1 74 ? -4.903 -20.694 14.151 1.00 27.47 ? 74 SER C N 1 ATOM 3855 C CA . SER C 1 74 ? -4.738 -21.967 14.844 1.00 28.41 ? 74 SER C CA 1 ATOM 3856 C C . SER C 1 74 ? -3.436 -22.098 15.608 1.00 28.40 ? 74 SER C C 1 ATOM 3857 O O . SER C 1 74 ? -2.364 -21.801 15.088 1.00 30.04 ? 74 SER C O 1 ATOM 3858 C CB . SER C 1 74 ? -4.864 -23.128 13.862 1.00 28.58 ? 74 SER C CB 1 ATOM 3859 O OG . SER C 1 74 ? -6.203 -23.563 13.806 1.00 34.29 ? 74 SER C OG 1 ATOM 3860 N N . ILE C 1 75 ? -3.540 -22.534 16.858 1.00 34.07 ? 75 ILE C N 1 ATOM 3861 C CA . ILE C 1 75 ? -2.368 -22.916 17.637 1.00 32.47 ? 75 ILE C CA 1 ATOM 3862 C C . ILE C 1 75 ? -2.509 -24.393 17.944 1.00 38.73 ? 75 ILE C C 1 ATOM 3863 O O . ILE C 1 75 ? -3.371 -24.780 18.733 1.00 38.45 ? 75 ILE C O 1 ATOM 3864 C CB . ILE C 1 75 ? -2.280 -22.143 18.956 1.00 33.86 ? 75 ILE C CB 1 ATOM 3865 C CG1 . ILE C 1 75 ? -2.547 -20.655 18.728 1.00 32.23 ? 75 ILE C CG1 1 ATOM 3866 C CG2 . ILE C 1 75 ? -0.919 -22.357 19.609 1.00 36.01 ? 75 ILE C CG2 1 ATOM 3867 C CD1 . ILE C 1 75 ? -2.488 -19.843 19.991 1.00 26.46 ? 75 ILE C CD1 1 ATOM 3868 N N . ASN C 1 76 ? -1.680 -25.221 17.314 1.00 39.19 ? 76 ASN C N 1 ATOM 3869 C CA . ASN C 1 76 ? -1.872 -26.669 17.396 1.00 51.35 ? 76 ASN C CA 1 ATOM 3870 C C . ASN C 1 76 ? -1.763 -27.246 18.816 1.00 48.63 ? 76 ASN C C 1 ATOM 3871 O O . ASN C 1 76 ? -2.586 -28.069 19.224 1.00 52.58 ? 76 ASN C O 1 ATOM 3872 C CB . ASN C 1 76 ? -0.993 -27.431 16.382 1.00 34.23 ? 76 ASN C CB 1 ATOM 3873 C CG . ASN C 1 76 ? 0.497 -27.317 16.671 1.00 49.62 ? 76 ASN C CG 1 ATOM 3874 O OD1 . ASN C 1 76 ? 0.913 -26.958 17.773 1.00 53.35 ? 76 ASN C OD1 1 ATOM 3875 N ND2 . ASN C 1 76 ? 1.312 -27.637 15.671 1.00 56.79 ? 76 ASN C ND2 1 ATOM 3876 N N . SER C 1 77 ? -0.760 -26.804 19.567 1.00 33.67 ? 77 SER C N 1 ATOM 3877 C CA . SER C 1 77 ? -0.606 -27.243 20.950 1.00 32.91 ? 77 SER C CA 1 ATOM 3878 C C . SER C 1 77 ? -0.352 -26.045 21.851 1.00 34.92 ? 77 SER C C 1 ATOM 3879 O O . SER C 1 77 ? 0.795 -25.636 22.057 1.00 33.90 ? 77 SER C O 1 ATOM 3880 C CB . SER C 1 77 ? 0.530 -28.254 21.077 1.00 29.77 ? 77 SER C CB 1 ATOM 3881 O OG . SER C 1 77 ? 0.584 -28.777 22.388 1.00 36.83 ? 77 SER C OG 1 ATOM 3882 N N . VAL C 1 78 ? -1.435 -25.492 22.386 1.00 25.13 ? 78 VAL C N 1 ATOM 3883 C CA . VAL C 1 78 ? -1.379 -24.244 23.137 1.00 32.15 ? 78 VAL C CA 1 ATOM 3884 C C . VAL C 1 78 ? -0.517 -24.335 24.407 1.00 35.63 ? 78 VAL C C 1 ATOM 3885 O O . VAL C 1 78 ? -0.492 -25.358 25.093 1.00 33.85 ? 78 VAL C O 1 ATOM 3886 C CB . VAL C 1 78 ? -2.803 -23.724 23.454 1.00 36.71 ? 78 VAL C CB 1 ATOM 3887 C CG1 . VAL C 1 78 ? -3.489 -24.614 24.481 1.00 27.62 ? 78 VAL C CG1 1 ATOM 3888 C CG2 . VAL C 1 78 ? -2.759 -22.276 23.918 1.00 37.74 ? 78 VAL C CG2 1 ATOM 3889 N N . GLU C 1 79 ? 0.217 -23.263 24.687 1.00 39.01 ? 79 GLU C N 1 ATOM 3890 C CA . GLU C 1 79 ? 1.093 -23.190 25.852 1.00 37.94 ? 79 GLU C CA 1 ATOM 3891 C C . GLU C 1 79 ? 0.708 -21.967 26.678 1.00 30.18 ? 79 GLU C C 1 ATOM 3892 O O . GLU C 1 79 ? 0.070 -21.046 26.165 1.00 27.72 ? 79 GLU C O 1 ATOM 3893 C CB . GLU C 1 79 ? 2.550 -23.071 25.406 1.00 37.50 ? 79 GLU C CB 1 ATOM 3894 C CG . GLU C 1 79 ? 2.921 -23.991 24.246 1.00 40.65 ? 79 GLU C CG 1 ATOM 3895 C CD . GLU C 1 79 ? 4.363 -23.821 23.789 1.00 48.42 ? 79 GLU C CD 1 ATOM 3896 O OE1 . GLU C 1 79 ? 4.939 -22.734 24.020 1.00 41.23 ? 79 GLU C OE1 1 ATOM 3897 O OE2 . GLU C 1 79 ? 4.919 -24.778 23.198 1.00 44.80 ? 79 GLU C OE2 1 ATOM 3898 N N . SER C 1 80 ? 1.094 -21.949 27.949 1.00 28.48 ? 80 SER C N 1 ATOM 3899 C CA . SER C 1 80 ? 0.763 -20.818 28.806 1.00 28.95 ? 80 SER C CA 1 ATOM 3900 C C . SER C 1 80 ? 1.429 -19.527 28.343 1.00 25.00 ? 80 SER C C 1 ATOM 3901 O O . SER C 1 80 ? 0.919 -18.443 28.594 1.00 30.15 ? 80 SER C O 1 ATOM 3902 C CB . SER C 1 80 ? 1.104 -21.120 30.261 1.00 35.80 ? 80 SER C CB 1 ATOM 3903 O OG . SER C 1 80 ? 2.297 -21.869 30.330 1.00 43.39 ? 80 SER C OG 1 ATOM 3904 N N . GLU C 1 81 ? 2.545 -19.635 27.633 1.00 28.47 ? 81 GLU C N 1 ATOM 3905 C CA . GLU C 1 81 ? 3.153 -18.455 27.019 1.00 27.24 ? 81 GLU C CA 1 ATOM 3906 C C . GLU C 1 81 ? 2.299 -17.866 25.889 1.00 29.84 ? 81 GLU C C 1 ATOM 3907 O O . GLU C 1 81 ? 2.569 -16.767 25.409 1.00 29.29 ? 81 GLU C O 1 ATOM 3908 C CB . GLU C 1 81 ? 4.563 -18.763 26.522 1.00 31.94 ? 81 GLU C CB 1 ATOM 3909 C CG . GLU C 1 81 ? 4.672 -20.020 25.686 1.00 42.01 ? 81 GLU C CG 1 ATOM 3910 C CD . GLU C 1 81 ? 6.100 -20.311 25.232 1.00 63.35 ? 81 GLU C CD 1 ATOM 3911 O OE1 . GLU C 1 81 ? 6.448 -19.984 24.068 1.00 63.48 ? 81 GLU C OE1 1 ATOM 3912 O OE2 . GLU C 1 81 ? 6.874 -20.878 26.038 1.00 75.32 ? 81 GLU C OE2 1 ATOM 3913 N N . ASP C 1 82 ? 1.257 -18.587 25.481 1.00 28.67 ? 82 ASP C N 1 ATOM 3914 C CA . ASP C 1 82 ? 0.347 -18.088 24.455 1.00 28.88 ? 82 ASP C CA 1 ATOM 3915 C C . ASP C 1 82 ? -0.802 -17.250 25.020 1.00 25.16 ? 82 ASP C C 1 ATOM 3916 O O . ASP C 1 82 ? -1.625 -16.749 24.265 1.00 28.32 ? 82 ASP C O 1 ATOM 3917 C CB . ASP C 1 82 ? -0.203 -19.233 23.598 1.00 25.20 ? 82 ASP C CB 1 ATOM 3918 C CG . ASP C 1 82 ? 0.887 -19.958 22.828 1.00 28.71 ? 82 ASP C CG 1 ATOM 3919 O OD1 . ASP C 1 82 ? 1.893 -19.306 22.450 1.00 31.56 ? 82 ASP C OD1 1 ATOM 3920 O OD2 . ASP C 1 82 ? 0.735 -21.179 22.597 1.00 27.98 ? 82 ASP C OD2 1 ATOM 3921 N N . ILE C 1 83 ? -0.864 -17.107 26.339 1.00 23.61 ? 83 ILE C N 1 ATOM 3922 C CA . ILE C 1 83 ? -1.852 -16.231 26.954 1.00 18.71 ? 83 ILE C CA 1 ATOM 3923 C C . ILE C 1 83 ? -1.683 -14.813 26.421 1.00 18.11 ? 83 ILE C C 1 ATOM 3924 O O . ILE C 1 83 ? -0.656 -14.176 26.642 1.00 14.67 ? 83 ILE C O 1 ATOM 3925 C CB . ILE C 1 83 ? -1.756 -16.252 28.501 1.00 27.44 ? 83 ILE C CB 1 ATOM 3926 C CG1 . ILE C 1 83 ? -2.206 -17.618 29.049 1.00 34.63 ? 83 ILE C CG1 1 ATOM 3927 C CG2 . ILE C 1 83 ? -2.609 -15.135 29.122 1.00 22.74 ? 83 ILE C CG2 1 ATOM 3928 C CD1 . ILE C 1 83 ? -1.821 -17.876 30.507 1.00 28.24 ? 83 ILE C CD1 1 ATOM 3929 N N . ALA C 1 84 ? -2.693 -14.340 25.694 1.00 20.17 ? 84 ALA C N 1 ATOM 3930 C CA . ALA C 1 84 ? -2.670 -13.018 25.093 1.00 17.15 ? 84 ALA C CA 1 ATOM 3931 C C . ALA C 1 84 ? -4.018 -12.752 24.473 1.00 23.50 ? 84 ALA C C 1 ATOM 3932 O O . ALA C 1 84 ? -4.906 -13.598 24.514 1.00 21.22 ? 84 ALA C O 1 ATOM 3933 C CB . ALA C 1 84 ? -1.600 -12.941 24.012 1.00 14.65 ? 84 ALA C CB 1 ATOM 3934 N N . ASP C 1 85 ? -4.177 -11.565 23.899 1.00 25.33 ? 85 ASP C N 1 ATOM 3935 C CA . ASP C 1 85 ? -5.320 -11.303 23.046 1.00 21.09 ? 85 ASP C CA 1 ATOM 3936 C C . ASP C 1 85 ? -4.908 -11.530 21.600 1.00 24.59 ? 85 ASP C C 1 ATOM 3937 O O . ASP C 1 85 ? -3.731 -11.394 21.255 1.00 27.28 ? 85 ASP C O 1 ATOM 3938 C CB . ASP C 1 85 ? -5.818 -9.888 23.257 1.00 26.97 ? 85 ASP C CB 1 ATOM 3939 C CG . ASP C 1 85 ? -6.263 -9.653 24.678 1.00 30.87 ? 85 ASP C CG 1 ATOM 3940 O OD1 . ASP C 1 85 ? -6.674 -10.635 25.333 1.00 27.72 ? 85 ASP C OD1 1 ATOM 3941 O OD2 . ASP C 1 85 ? -6.195 -8.494 25.139 1.00 33.38 ? 85 ASP C OD2 1 ATOM 3942 N N . TYR C 1 86 ? -5.872 -11.890 20.761 1.00 21.20 ? 86 TYR C N 1 ATOM 3943 C CA . TYR C 1 86 ? -5.598 -12.190 19.362 1.00 21.34 ? 86 TYR C CA 1 ATOM 3944 C C . TYR C 1 86 ? -6.513 -11.414 18.424 1.00 20.23 ? 86 TYR C C 1 ATOM 3945 O O . TYR C 1 86 ? -7.731 -11.411 18.582 1.00 22.78 ? 86 TYR C O 1 ATOM 3946 C CB . TYR C 1 86 ? -5.679 -13.699 19.117 1.00 23.66 ? 86 TYR C CB 1 ATOM 3947 C CG . TYR C 1 86 ? -4.566 -14.453 19.806 1.00 24.59 ? 86 TYR C CG 1 ATOM 3948 C CD1 . TYR C 1 86 ? -4.714 -14.915 21.111 1.00 19.69 ? 86 TYR C CD1 1 ATOM 3949 C CD2 . TYR C 1 86 ? -3.353 -14.670 19.165 1.00 21.25 ? 86 TYR C CD2 1 ATOM 3950 C CE1 . TYR C 1 86 ? -3.694 -15.601 21.749 1.00 19.26 ? 86 TYR C CE1 1 ATOM 3951 C CE2 . TYR C 1 86 ? -2.320 -15.346 19.798 1.00 25.09 ? 86 TYR C CE2 1 ATOM 3952 C CZ . TYR C 1 86 ? -2.493 -15.813 21.091 1.00 26.24 ? 86 TYR C CZ 1 ATOM 3953 O OH . TYR C 1 86 ? -1.464 -16.494 21.719 1.00 23.03 ? 86 TYR C OH 1 ATOM 3954 N N . TYR C 1 87 ? -5.909 -10.742 17.450 1.00 23.21 ? 87 TYR C N 1 ATOM 3955 C CA . TYR C 1 87 ? -6.653 -9.850 16.568 1.00 23.62 ? 87 TYR C CA 1 ATOM 3956 C C . TYR C 1 87 ? -6.539 -10.252 15.114 1.00 22.68 ? 87 TYR C C 1 ATOM 3957 O O . TYR C 1 87 ? -5.490 -10.722 14.663 1.00 24.40 ? 87 TYR C O 1 ATOM 3958 C CB . TYR C 1 87 ? -6.184 -8.392 16.724 1.00 18.72 ? 87 TYR C CB 1 ATOM 3959 C CG . TYR C 1 87 ? -6.500 -7.800 18.077 1.00 22.20 ? 87 TYR C CG 1 ATOM 3960 C CD1 . TYR C 1 87 ? -5.583 -7.869 19.114 1.00 24.01 ? 87 TYR C CD1 1 ATOM 3961 C CD2 . TYR C 1 87 ? -7.722 -7.192 18.323 1.00 23.70 ? 87 TYR C CD2 1 ATOM 3962 C CE1 . TYR C 1 87 ? -5.864 -7.343 20.353 1.00 26.54 ? 87 TYR C CE1 1 ATOM 3963 C CE2 . TYR C 1 87 ? -8.012 -6.663 19.569 1.00 29.45 ? 87 TYR C CE2 1 ATOM 3964 C CZ . TYR C 1 87 ? -7.074 -6.744 20.577 1.00 23.42 ? 87 TYR C CZ 1 ATOM 3965 O OH . TYR C 1 87 ? -7.336 -6.222 21.813 1.00 31.05 ? 87 TYR C OH 1 ATOM 3966 N N . CYS C 1 88 ? -7.623 -10.049 14.380 1.00 16.23 ? 88 CYS C N 1 ATOM 3967 C CA . CYS C 1 88 ? -7.553 -10.137 12.941 1.00 19.60 ? 88 CYS C CA 1 ATOM 3968 C C . CYS C 1 88 ? -7.706 -8.748 12.293 1.00 26.31 ? 88 CYS C C 1 ATOM 3969 O O . CYS C 1 88 ? -8.312 -7.831 12.859 1.00 21.37 ? 88 CYS C O 1 ATOM 3970 C CB . CYS C 1 88 ? -8.574 -11.145 12.409 1.00 20.27 ? 88 CYS C CB 1 ATOM 3971 S SG . CYS C 1 88 ? -10.284 -10.644 12.599 1.00 26.79 ? 88 CYS C SG 1 ATOM 3972 N N . GLN C 1 89 ? -7.126 -8.607 11.106 1.00 23.52 ? 89 GLN C N 1 ATOM 3973 C CA . GLN C 1 89 ? -7.140 -7.351 10.364 1.00 20.86 ? 89 GLN C CA 1 ATOM 3974 C C . GLN C 1 89 ? -7.436 -7.678 8.913 1.00 21.76 ? 89 GLN C C 1 ATOM 3975 O O . GLN C 1 89 ? -6.909 -8.654 8.392 1.00 21.31 ? 89 GLN C O 1 ATOM 3976 C CB . GLN C 1 89 ? -5.775 -6.668 10.464 1.00 19.86 ? 89 GLN C CB 1 ATOM 3977 C CG . GLN C 1 89 ? -5.496 -5.639 9.374 1.00 19.55 ? 89 GLN C CG 1 ATOM 3978 C CD . GLN C 1 89 ? -4.003 -5.308 9.255 1.00 23.43 ? 89 GLN C CD 1 ATOM 3979 O OE1 . GLN C 1 89 ? -3.152 -6.179 9.419 1.00 20.87 ? 89 GLN C OE1 1 ATOM 3980 N NE2 . GLN C 1 89 ? -3.687 -4.047 8.975 1.00 22.35 ? 89 GLN C NE2 1 ATOM 3981 N N . GLN C 1 90 ? -8.290 -6.888 8.268 1.00 19.48 ? 90 GLN C N 1 ATOM 3982 C CA . GLN C 1 90 ? -8.517 -7.048 6.836 1.00 17.54 ? 90 GLN C CA 1 ATOM 3983 C C . GLN C 1 90 ? -7.944 -5.846 6.114 1.00 20.67 ? 90 GLN C C 1 ATOM 3984 O O . GLN C 1 90 ? -7.970 -4.730 6.645 1.00 17.84 ? 90 GLN C O 1 ATOM 3985 C CB . GLN C 1 90 ? -10.008 -7.216 6.505 1.00 18.70 ? 90 GLN C CB 1 ATOM 3986 C CG . GLN C 1 90 ? -10.870 -5.966 6.651 1.00 15.90 ? 90 GLN C CG 1 ATOM 3987 C CD . GLN C 1 90 ? -10.725 -4.972 5.489 1.00 24.10 ? 90 GLN C CD 1 ATOM 3988 O OE1 . GLN C 1 90 ? -10.448 -5.356 4.344 1.00 16.53 ? 90 GLN C OE1 1 ATOM 3989 N NE2 . GLN C 1 90 ? -10.886 -3.680 5.796 1.00 24.44 ? 90 GLN C NE2 1 ATOM 3990 N N . ASN C 1 91 ? -7.447 -6.067 4.897 1.00 24.73 ? 91 ASN C N 1 ATOM 3991 C CA . ASN C 1 91 ? -7.017 -4.963 4.037 1.00 23.73 ? 91 ASN C CA 1 ATOM 3992 C C . ASN C 1 91 ? -7.393 -5.137 2.557 1.00 26.23 ? 91 ASN C C 1 ATOM 3993 O O . ASN C 1 91 ? -6.714 -4.640 1.665 1.00 27.30 ? 91 ASN C O 1 ATOM 3994 C CB . ASN C 1 91 ? -5.519 -4.702 4.186 1.00 20.67 ? 91 ASN C CB 1 ATOM 3995 C CG . ASN C 1 91 ? -5.091 -3.393 3.554 1.00 24.69 ? 91 ASN C CG 1 ATOM 3996 O OD1 . ASN C 1 91 ? -5.741 -2.352 3.724 1.00 24.32 ? 91 ASN C OD1 1 ATOM 3997 N ND2 . ASN C 1 91 ? -4.006 -3.443 2.796 1.00 22.25 ? 91 ASN C ND2 1 ATOM 3998 N N . ASN C 1 92 ? -8.487 -5.838 2.297 1.00 27.55 ? 92 ASN C N 1 ATOM 3999 C CA . ASN C 1 92 ? -9.031 -5.894 0.944 1.00 27.92 ? 92 ASN C CA 1 ATOM 4000 C C . ASN C 1 92 ? -9.731 -4.572 0.587 1.00 30.73 ? 92 ASN C C 1 ATOM 4001 O O . ASN C 1 92 ? -9.621 -4.072 -0.535 1.00 28.98 ? 92 ASN C O 1 ATOM 4002 C CB . ASN C 1 92 ? -9.982 -7.085 0.797 1.00 24.97 ? 92 ASN C CB 1 ATOM 4003 C CG . ASN C 1 92 ? -10.494 -7.258 -0.630 1.00 26.33 ? 92 ASN C CG 1 ATOM 4004 O OD1 . ASN C 1 92 ? -9.809 -7.815 -1.491 1.00 22.37 ? 92 ASN C OD1 1 ATOM 4005 N ND2 . ASN C 1 92 ? -11.715 -6.802 -0.873 1.00 28.53 ? 92 ASN C ND2 1 ATOM 4006 N N . ASN C 1 93 ? -10.445 -4.006 1.553 1.00 24.24 ? 93 ASN C N 1 ATOM 4007 C CA . ASN C 1 93 ? -11.113 -2.732 1.353 1.00 27.89 ? 93 ASN C CA 1 ATOM 4008 C C . ASN C 1 93 ? -10.507 -1.629 2.203 1.00 24.69 ? 93 ASN C C 1 ATOM 4009 O O . ASN C 1 93 ? -10.066 -1.879 3.308 1.00 28.41 ? 93 ASN C O 1 ATOM 4010 C CB . ASN C 1 93 ? -12.615 -2.865 1.599 1.00 26.12 ? 93 ASN C CB 1 ATOM 4011 C CG . ASN C 1 93 ? -13.305 -3.674 0.510 1.00 44.95 ? 93 ASN C CG 1 ATOM 4012 O OD1 . ASN C 1 93 ? -13.248 -4.912 0.493 1.00 44.22 ? 93 ASN C OD1 1 ATOM 4013 N ND2 . ASN C 1 93 ? -13.946 -2.976 -0.421 1.00 44.59 ? 93 ASN C ND2 1 ATOM 4014 N N . TRP C 1 94 ? -10.446 -0.420 1.657 1.00 28.08 ? 94 TRP C N 1 ATOM 4015 C CA . TRP C 1 94 ? -9.893 0.718 2.374 1.00 23.86 ? 94 TRP C CA 1 ATOM 4016 C C . TRP C 1 94 ? -11.007 1.356 3.179 1.00 23.64 ? 94 TRP C C 1 ATOM 4017 O O . TRP C 1 94 ? -12.075 1.637 2.643 1.00 29.11 ? 94 TRP C O 1 ATOM 4018 C CB . TRP C 1 94 ? -9.293 1.746 1.399 1.00 20.08 ? 94 TRP C CB 1 ATOM 4019 C CG . TRP C 1 94 ? -8.517 2.860 2.058 1.00 22.66 ? 94 TRP C CG 1 ATOM 4020 C CD1 . TRP C 1 94 ? -7.160 2.933 2.221 1.00 27.48 ? 94 TRP C CD1 1 ATOM 4021 C CD2 . TRP C 1 94 ? -9.055 4.051 2.657 1.00 23.77 ? 94 TRP C CD2 1 ATOM 4022 N NE1 . TRP C 1 94 ? -6.822 4.099 2.870 1.00 19.37 ? 94 TRP C NE1 1 ATOM 4023 C CE2 . TRP C 1 94 ? -7.965 4.799 3.152 1.00 18.80 ? 94 TRP C CE2 1 ATOM 4024 C CE3 . TRP C 1 94 ? -10.350 4.559 2.817 1.00 22.01 ? 94 TRP C CE3 1 ATOM 4025 C CZ2 . TRP C 1 94 ? -8.134 6.028 3.787 1.00 19.13 ? 94 TRP C CZ2 1 ATOM 4026 C CZ3 . TRP C 1 94 ? -10.514 5.777 3.458 1.00 20.94 ? 94 TRP C CZ3 1 ATOM 4027 C CH2 . TRP C 1 94 ? -9.414 6.497 3.930 1.00 20.72 ? 94 TRP C CH2 1 ATOM 4028 N N . PRO C 1 95 ? -10.743 1.637 4.463 1.00 29.12 ? 95 PRO C N 1 ATOM 4029 C CA . PRO C 1 95 ? -9.420 1.462 5.080 1.00 18.40 ? 95 PRO C CA 1 ATOM 4030 C C . PRO C 1 95 ? -9.261 0.126 5.786 1.00 17.81 ? 95 PRO C C 1 ATOM 4031 O O . PRO C 1 95 ? -10.244 -0.589 6.027 1.00 19.21 ? 95 PRO C O 1 ATOM 4032 C CB . PRO C 1 95 ? -9.383 2.591 6.103 1.00 27.44 ? 95 PRO C CB 1 ATOM 4033 C CG . PRO C 1 95 ? -10.845 2.674 6.581 1.00 31.18 ? 95 PRO C CG 1 ATOM 4034 C CD . PRO C 1 95 ? -11.709 2.272 5.384 1.00 29.45 ? 95 PRO C CD 1 ATOM 4035 N N . THR C 1 96 ? -8.022 -0.205 6.124 1.00 17.70 ? 96 THR C N 1 ATOM 4036 C CA . THR C 1 96 ? -7.767 -1.411 6.882 1.00 17.32 ? 96 THR C CA 1 ATOM 4037 C C . THR C 1 96 ? -8.500 -1.334 8.225 1.00 21.69 ? 96 THR C C 1 ATOM 4038 O O . THR C 1 96 ? -8.546 -0.281 8.863 1.00 21.96 ? 96 THR C O 1 ATOM 4039 C CB . THR C 1 96 ? -6.260 -1.666 7.052 1.00 16.15 ? 96 THR C CB 1 ATOM 4040 O OG1 . THR C 1 96 ? -6.047 -2.956 7.626 1.00 11.77 ? 96 THR C OG1 1 ATOM 4041 C CG2 . THR C 1 96 ? -5.620 -0.611 7.913 1.00 14.77 ? 96 THR C CG2 1 ATOM 4042 N N . THR C 1 97 ? -9.124 -2.438 8.621 1.00 20.48 ? 97 THR C N 1 ATOM 4043 C CA . THR C 1 97 ? -9.882 -2.471 9.854 1.00 17.56 ? 97 THR C CA 1 ATOM 4044 C C . THR C 1 97 ? -9.547 -3.728 10.628 1.00 24.15 ? 97 THR C C 1 ATOM 4045 O O . THR C 1 97 ? -9.174 -4.746 10.045 1.00 21.11 ? 97 THR C O 1 ATOM 4046 C CB . THR C 1 97 ? -11.404 -2.409 9.597 1.00 20.34 ? 97 THR C CB 1 ATOM 4047 O OG1 . THR C 1 97 ? -11.779 -3.435 8.675 1.00 23.46 ? 97 THR C OG1 1 ATOM 4048 C CG2 . THR C 1 97 ? -11.801 -1.063 9.022 1.00 19.96 ? 97 THR C CG2 1 ATOM 4049 N N . PHE C 1 98 ? -9.679 -3.644 11.947 1.00 23.51 ? 98 PHE C N 1 ATOM 4050 C CA . PHE C 1 98 ? -9.340 -4.752 12.832 1.00 23.02 ? 98 PHE C CA 1 ATOM 4051 C C . PHE C 1 98 ? -10.589 -5.335 13.497 1.00 21.12 ? 98 PHE C C 1 ATOM 4052 O O . PHE C 1 98 ? -11.574 -4.626 13.699 1.00 22.92 ? 98 PHE C O 1 ATOM 4053 C CB . PHE C 1 98 ? -8.385 -4.276 13.927 1.00 14.40 ? 98 PHE C CB 1 ATOM 4054 C CG . PHE C 1 98 ? -7.018 -3.898 13.442 1.00 13.64 ? 98 PHE C CG 1 ATOM 4055 C CD1 . PHE C 1 98 ? -6.764 -2.625 12.963 1.00 16.68 ? 98 PHE C CD1 1 ATOM 4056 C CD2 . PHE C 1 98 ? -5.969 -4.799 13.517 1.00 16.86 ? 98 PHE C CD2 1 ATOM 4057 C CE1 . PHE C 1 98 ? -5.491 -2.255 12.548 1.00 12.58 ? 98 PHE C CE1 1 ATOM 4058 C CE2 . PHE C 1 98 ? -4.690 -4.445 13.099 1.00 13.84 ? 98 PHE C CE2 1 ATOM 4059 C CZ . PHE C 1 98 ? -4.450 -3.169 12.611 1.00 15.34 ? 98 PHE C CZ 1 ATOM 4060 N N . GLY C 1 99 ? -10.537 -6.617 13.854 1.00 21.64 ? 99 GLY C N 1 ATOM 4061 C CA . GLY C 1 99 ? -11.570 -7.220 14.687 1.00 24.06 ? 99 GLY C CA 1 ATOM 4062 C C . GLY C 1 99 ? -11.506 -6.707 16.125 1.00 24.55 ? 99 GLY C C 1 ATOM 4063 O O . GLY C 1 99 ? -10.636 -5.902 16.473 1.00 24.59 ? 99 GLY C O 1 ATOM 4064 N N . ALA C 1 100 ? -12.421 -7.173 16.970 1.00 26.13 ? 100 ALA C N 1 ATOM 4065 C CA . ALA C 1 100 ? -12.508 -6.685 18.347 1.00 20.43 ? 100 ALA C CA 1 ATOM 4066 C C . ALA C 1 100 ? -11.598 -7.485 19.272 1.00 26.29 ? 100 ALA C C 1 ATOM 4067 O O . ALA C 1 100 ? -11.312 -7.076 20.398 1.00 21.28 ? 100 ALA C O 1 ATOM 4068 C CB . ALA C 1 100 ? -13.939 -6.727 18.839 1.00 8.25 ? 100 ALA C CB 1 ATOM 4069 N N . GLY C 1 101 ? -11.154 -8.640 18.797 1.00 26.02 ? 101 GLY C N 1 ATOM 4070 C CA . GLY C 1 101 ? -10.213 -9.443 19.553 1.00 21.23 ? 101 GLY C CA 1 ATOM 4071 C C . GLY C 1 101 ? -10.857 -10.610 20.264 1.00 21.78 ? 101 GLY C C 1 ATOM 4072 O O . GLY C 1 101 ? -12.059 -10.613 20.521 1.00 25.74 ? 101 GLY C O 1 ATOM 4073 N N . THR C 1 102 ? -10.040 -11.612 20.564 1.00 24.39 ? 102 THR C N 1 ATOM 4074 C CA . THR C 1 102 ? -10.449 -12.756 21.368 1.00 27.13 ? 102 THR C CA 1 ATOM 4075 C C . THR C 1 102 ? -9.408 -12.966 22.459 1.00 22.86 ? 102 THR C C 1 ATOM 4076 O O . THR C 1 102 ? -8.221 -13.085 22.167 1.00 23.14 ? 102 THR C O 1 ATOM 4077 C CB . THR C 1 102 ? -10.570 -14.049 20.511 1.00 30.12 ? 102 THR C CB 1 ATOM 4078 O OG1 . THR C 1 102 ? -11.783 -14.010 19.745 1.00 33.49 ? 102 THR C OG1 1 ATOM 4079 C CG2 . THR C 1 102 ? -10.560 -15.307 21.396 1.00 26.36 ? 102 THR C CG2 1 ATOM 4080 N N . LYS C 1 103 ? -9.865 -12.994 23.710 1.00 29.45 ? 103 LYS C N 1 ATOM 4081 C CA . LYS C 1 103 ? -9.037 -13.260 24.896 1.00 27.58 ? 103 LYS C CA 1 ATOM 4082 C C . LYS C 1 103 ? -8.744 -14.751 25.002 1.00 22.95 ? 103 LYS C C 1 ATOM 4083 O O . LYS C 1 103 ? -9.670 -15.557 25.074 1.00 29.18 ? 103 LYS C O 1 ATOM 4084 C CB . LYS C 1 103 ? -9.825 -12.840 26.147 1.00 31.37 ? 103 LYS C CB 1 ATOM 4085 C CG . LYS C 1 103 ? -9.114 -11.927 27.137 1.00 23.66 ? 103 LYS C CG 1 ATOM 4086 C CD . LYS C 1 103 ? -8.306 -12.710 28.129 1.00 30.94 ? 103 LYS C CD 1 ATOM 4087 C CE . LYS C 1 103 ? -7.833 -11.817 29.261 1.00 34.09 ? 103 LYS C CE 1 ATOM 4088 N NZ . LYS C 1 103 ? -8.929 -11.345 30.143 1.00 30.49 ? 103 LYS C NZ 1 ATOM 4089 N N . LEU C 1 104 ? -7.475 -15.134 25.016 1.00 23.51 ? 104 LEU C N 1 ATOM 4090 C CA . LEU C 1 104 ? -7.126 -16.532 25.275 1.00 20.58 ? 104 LEU C CA 1 ATOM 4091 C C . LEU C 1 104 ? -6.836 -16.736 26.756 1.00 21.81 ? 104 LEU C C 1 ATOM 4092 O O . LEU C 1 104 ? -5.954 -16.085 27.321 1.00 20.54 ? 104 LEU C O 1 ATOM 4093 C CB . LEU C 1 104 ? -5.920 -16.973 24.445 1.00 16.75 ? 104 LEU C CB 1 ATOM 4094 C CG . LEU C 1 104 ? -5.488 -18.441 24.563 1.00 24.18 ? 104 LEU C CG 1 ATOM 4095 C CD1 . LEU C 1 104 ? -6.619 -19.397 24.193 1.00 18.92 ? 104 LEU C CD1 1 ATOM 4096 C CD2 . LEU C 1 104 ? -4.227 -18.729 23.725 1.00 19.62 ? 104 LEU C CD2 1 ATOM 4097 N N . GLU C 1 105 ? -7.597 -17.631 27.376 1.00 23.58 ? 105 GLU C N 1 ATOM 4098 C CA . GLU C 1 105 ? -7.388 -18.000 28.775 1.00 31.31 ? 105 GLU C CA 1 ATOM 4099 C C . GLU C 1 105 ? -6.983 -19.458 28.897 1.00 28.96 ? 105 GLU C C 1 ATOM 4100 O O . GLU C 1 105 ? -7.464 -20.318 28.151 1.00 24.32 ? 105 GLU C O 1 ATOM 4101 C CB . GLU C 1 105 ? -8.666 -17.801 29.578 1.00 26.84 ? 105 GLU C CB 1 ATOM 4102 C CG . GLU C 1 105 ? -9.238 -16.403 29.519 1.00 37.68 ? 105 GLU C CG 1 ATOM 4103 C CD . GLU C 1 105 ? -10.213 -16.152 30.656 1.00 43.81 ? 105 GLU C CD 1 ATOM 4104 O OE1 . GLU C 1 105 ? -11.059 -17.033 30.933 1.00 36.14 ? 105 GLU C OE1 1 ATOM 4105 O OE2 . GLU C 1 105 ? -10.111 -15.084 31.287 1.00 46.21 ? 105 GLU C OE2 1 ATOM 4106 N N . LEU C 1 106 ? -6.115 -19.748 29.852 1.00 22.59 ? 106 LEU C N 1 ATOM 4107 C CA . LEU C 1 106 ? -5.735 -21.133 30.068 1.00 25.25 ? 106 LEU C CA 1 ATOM 4108 C C . LEU C 1 106 ? -6.307 -21.740 31.337 1.00 26.43 ? 106 LEU C C 1 ATOM 4109 O O . LEU C 1 106 ? -6.344 -21.110 32.384 1.00 28.06 ? 106 LEU C O 1 ATOM 4110 C CB . LEU C 1 106 ? -4.227 -21.329 29.984 1.00 25.87 ? 106 LEU C CB 1 ATOM 4111 C CG . LEU C 1 106 ? -3.895 -21.878 28.590 1.00 28.80 ? 106 LEU C CG 1 ATOM 4112 C CD1 . LEU C 1 106 ? -4.129 -20.805 27.519 1.00 31.55 ? 106 LEU C CD1 1 ATOM 4113 C CD2 . LEU C 1 106 ? -2.489 -22.421 28.521 1.00 33.21 ? 106 LEU C CD2 1 ATOM 4114 N N . LYS C 1 107 ? -6.791 -22.967 31.209 1.00 27.88 ? 107 LYS C N 1 ATOM 4115 C CA . LYS C 1 107 ? -7.272 -23.722 32.343 1.00 27.73 ? 107 LYS C CA 1 ATOM 4116 C C . LYS C 1 107 ? -6.080 -24.362 33.026 1.00 33.88 ? 107 LYS C C 1 ATOM 4117 O O . LYS C 1 107 ? -5.076 -24.669 32.382 1.00 29.78 ? 107 LYS C O 1 ATOM 4118 C CB . LYS C 1 107 ? -8.252 -24.801 31.885 1.00 27.40 ? 107 LYS C CB 1 ATOM 4119 C CG . LYS C 1 107 ? -9.629 -24.273 31.506 1.00 30.35 ? 107 LYS C CG 1 ATOM 4120 C CD . LYS C 1 107 ? -10.414 -25.324 30.746 1.00 44.83 ? 107 LYS C CD 1 ATOM 4121 C CE . LYS C 1 107 ? -11.665 -24.729 30.123 1.00 51.86 ? 107 LYS C CE 1 ATOM 4122 N NZ . LYS C 1 107 ? -12.265 -25.669 29.136 1.00 48.66 ? 107 LYS C NZ 1 ATOM 4123 N N . ARG C 1 108 ? -6.188 -24.536 34.336 1.00 25.50 ? 108 ARG C N 1 ATOM 4124 C CA . ARG C 1 108 ? -5.203 -25.285 35.083 1.00 21.51 ? 108 ARG C CA 1 ATOM 4125 C C . ARG C 1 108 ? -5.841 -25.766 36.385 1.00 24.38 ? 108 ARG C C 1 ATOM 4126 O O . ARG C 1 108 ? -6.972 -25.412 36.711 1.00 27.48 ? 108 ARG C O 1 ATOM 4127 C CB . ARG C 1 108 ? -3.948 -24.445 35.355 1.00 18.36 ? 108 ARG C CB 1 ATOM 4128 C CG . ARG C 1 108 ? -4.192 -23.168 36.143 1.00 18.68 ? 108 ARG C CG 1 ATOM 4129 C CD . ARG C 1 108 ? -2.995 -22.834 37.024 1.00 20.15 ? 108 ARG C CD 1 ATOM 4130 N NE . ARG C 1 108 ? -2.886 -23.751 38.160 1.00 17.35 ? 108 ARG C NE 1 ATOM 4131 C CZ . ARG C 1 108 ? -1.737 -24.115 38.718 1.00 21.87 ? 108 ARG C CZ 1 ATOM 4132 N NH1 . ARG C 1 108 ? -0.585 -23.645 38.253 1.00 26.67 ? 108 ARG C NH1 1 ATOM 4133 N NH2 . ARG C 1 108 ? -1.732 -24.966 39.734 1.00 22.20 ? 108 ARG C NH2 1 ATOM 4134 N N . THR C 1 109 ? -5.109 -26.587 37.117 1.00 18.66 ? 109 THR C N 1 ATOM 4135 C CA . THR C 1 109 ? -5.589 -27.095 38.378 1.00 20.36 ? 109 THR C CA 1 ATOM 4136 C C . THR C 1 109 ? -5.691 -25.958 39.376 1.00 22.15 ? 109 THR C C 1 ATOM 4137 O O . THR C 1 109 ? -4.864 -25.043 39.385 1.00 26.79 ? 109 THR C O 1 ATOM 4138 C CB . THR C 1 109 ? -4.643 -28.179 38.948 1.00 25.23 ? 109 THR C CB 1 ATOM 4139 O OG1 . THR C 1 109 ? -3.340 -27.619 39.125 1.00 19.23 ? 109 THR C OG1 1 ATOM 4140 C CG2 . THR C 1 109 ? -4.561 -29.374 38.007 1.00 11.70 ? 109 THR C CG2 1 ATOM 4141 N N . VAL C 1 110 ? -6.734 -26.022 40.189 1.00 16.31 ? 110 VAL C N 1 ATOM 4142 C CA . VAL C 1 110 ? -6.887 -25.180 41.361 1.00 19.25 ? 110 VAL C CA 1 ATOM 4143 C C . VAL C 1 110 ? -5.576 -25.033 42.161 1.00 22.03 ? 110 VAL C C 1 ATOM 4144 O O . VAL C 1 110 ? -4.899 -26.012 42.454 1.00 23.23 ? 110 VAL C O 1 ATOM 4145 C CB . VAL C 1 110 ? -7.978 -25.760 42.286 1.00 18.70 ? 110 VAL C CB 1 ATOM 4146 C CG1 . VAL C 1 110 ? -8.130 -24.923 43.525 1.00 22.47 ? 110 VAL C CG1 1 ATOM 4147 C CG2 . VAL C 1 110 ? -9.305 -25.873 41.539 1.00 14.58 ? 110 VAL C CG2 1 ATOM 4148 N N . ALA C 1 111 ? -5.228 -23.795 42.491 1.00 19.58 ? 111 ALA C N 1 ATOM 4149 C CA . ALA C 1 111 ? -4.112 -23.502 43.371 1.00 18.52 ? 111 ALA C CA 1 ATOM 4150 C C . ALA C 1 111 ? -4.554 -22.436 44.360 1.00 22.76 ? 111 ALA C C 1 ATOM 4151 O O . ALA C 1 111 ? -5.044 -21.378 43.967 1.00 22.52 ? 111 ALA C O 1 ATOM 4152 C CB . ALA C 1 111 ? -2.920 -23.012 42.584 1.00 16.41 ? 111 ALA C CB 1 ATOM 4153 N N . ALA C 1 112 ? -4.386 -22.729 45.646 1.00 23.63 ? 112 ALA C N 1 ATOM 4154 C CA . ALA C 1 112 ? -4.781 -21.818 46.704 1.00 19.51 ? 112 ALA C CA 1 ATOM 4155 C C . ALA C 1 112 ? -3.811 -20.645 46.760 1.00 20.90 ? 112 ALA C C 1 ATOM 4156 O O . ALA C 1 112 ? -2.628 -20.806 46.479 1.00 25.77 ? 112 ALA C O 1 ATOM 4157 C CB . ALA C 1 112 ? -4.807 -22.549 48.023 1.00 27.31 ? 112 ALA C CB 1 ATOM 4158 N N . PRO C 1 113 ? -4.309 -19.450 47.120 1.00 22.95 ? 113 PRO C N 1 ATOM 4159 C CA . PRO C 1 113 ? -3.426 -18.289 47.203 1.00 21.41 ? 113 PRO C CA 1 ATOM 4160 C C . PRO C 1 113 ? -2.616 -18.309 48.473 1.00 22.84 ? 113 PRO C C 1 ATOM 4161 O O . PRO C 1 113 ? -3.125 -18.704 49.529 1.00 24.15 ? 113 PRO C O 1 ATOM 4162 C CB . PRO C 1 113 ? -4.405 -17.114 47.272 1.00 19.24 ? 113 PRO C CB 1 ATOM 4163 C CG . PRO C 1 113 ? -5.594 -17.683 47.958 1.00 21.88 ? 113 PRO C CG 1 ATOM 4164 C CD . PRO C 1 113 ? -5.707 -19.085 47.411 1.00 28.86 ? 113 PRO C CD 1 ATOM 4165 N N . SER C 1 114 ? -1.361 -17.895 48.355 1.00 18.74 ? 114 SER C N 1 ATOM 4166 C CA . SER C 1 114 ? -0.564 -17.518 49.507 1.00 17.75 ? 114 SER C CA 1 ATOM 4167 C C . SER C 1 114 ? -0.926 -16.074 49.849 1.00 22.28 ? 114 SER C C 1 ATOM 4168 O O . SER C 1 114 ? -0.945 -15.207 48.966 1.00 21.00 ? 114 SER C O 1 ATOM 4169 C CB . SER C 1 114 ? 0.916 -17.625 49.175 1.00 9.99 ? 114 SER C CB 1 ATOM 4170 O OG . SER C 1 114 ? 1.226 -18.952 48.818 1.00 20.55 ? 114 SER C OG 1 ATOM 4171 N N . VAL C 1 115 ? -1.218 -15.826 51.121 1.00 14.95 ? 115 VAL C N 1 ATOM 4172 C CA . VAL C 1 115 ? -1.688 -14.519 51.574 1.00 16.54 ? 115 VAL C CA 1 ATOM 4173 C C . VAL C 1 115 ? -0.602 -13.801 52.395 1.00 19.10 ? 115 VAL C C 1 ATOM 4174 O O . VAL C 1 115 ? 0.163 -14.450 53.101 1.00 15.11 ? 115 VAL C O 1 ATOM 4175 C CB . VAL C 1 115 ? -2.980 -14.668 52.433 1.00 16.39 ? 115 VAL C CB 1 ATOM 4176 C CG1 . VAL C 1 115 ? -3.560 -13.311 52.805 1.00 11.95 ? 115 VAL C CG1 1 ATOM 4177 C CG2 . VAL C 1 115 ? -4.010 -15.507 51.701 1.00 10.39 ? 115 VAL C CG2 1 ATOM 4178 N N . PHE C 1 116 ? -0.542 -12.472 52.295 1.00 14.24 ? 116 PHE C N 1 ATOM 4179 C CA . PHE C 1 116 ? 0.437 -11.660 53.017 1.00 14.06 ? 116 PHE C CA 1 ATOM 4180 C C . PHE C 1 116 ? -0.179 -10.313 53.335 1.00 23.23 ? 116 PHE C C 1 ATOM 4181 O O . PHE C 1 116 ? -0.824 -9.701 52.465 1.00 21.03 ? 116 PHE C O 1 ATOM 4182 C CB . PHE C 1 116 ? 1.668 -11.370 52.154 1.00 13.75 ? 116 PHE C CB 1 ATOM 4183 C CG . PHE C 1 116 ? 2.417 -12.588 51.691 1.00 12.43 ? 116 PHE C CG 1 ATOM 4184 C CD1 . PHE C 1 116 ? 2.104 -13.194 50.491 1.00 10.98 ? 116 PHE C CD1 1 ATOM 4185 C CD2 . PHE C 1 116 ? 3.469 -13.084 52.431 1.00 11.93 ? 116 PHE C CD2 1 ATOM 4186 C CE1 . PHE C 1 116 ? 2.806 -14.293 50.051 1.00 14.92 ? 116 PHE C CE1 1 ATOM 4187 C CE2 . PHE C 1 116 ? 4.187 -14.175 51.992 1.00 15.48 ? 116 PHE C CE2 1 ATOM 4188 C CZ . PHE C 1 116 ? 3.851 -14.787 50.800 1.00 13.73 ? 116 PHE C CZ 1 ATOM 4189 N N . ILE C 1 117 ? 0.031 -9.842 54.563 1.00 18.69 ? 117 ILE C N 1 ATOM 4190 C CA . ILE C 1 117 ? -0.465 -8.532 54.960 1.00 20.50 ? 117 ILE C CA 1 ATOM 4191 C C . ILE C 1 117 ? 0.687 -7.568 55.242 1.00 21.35 ? 117 ILE C C 1 ATOM 4192 O O . ILE C 1 117 ? 1.718 -7.969 55.768 1.00 23.24 ? 117 ILE C O 1 ATOM 4193 C CB . ILE C 1 117 ? -1.431 -8.617 56.164 1.00 23.24 ? 117 ILE C CB 1 ATOM 4194 C CG1 . ILE C 1 117 ? -2.177 -7.295 56.351 1.00 16.20 ? 117 ILE C CG1 1 ATOM 4195 C CG2 . ILE C 1 117 ? -0.700 -9.027 57.427 1.00 14.57 ? 117 ILE C CG2 1 ATOM 4196 C CD1 . ILE C 1 117 ? -3.276 -7.360 57.390 1.00 21.02 ? 117 ILE C CD1 1 ATOM 4197 N N . PHE C 1 118 ? 0.499 -6.309 54.856 1.00 21.91 ? 118 PHE C N 1 ATOM 4198 C CA . PHE C 1 118 ? 1.508 -5.260 54.990 1.00 18.12 ? 118 PHE C CA 1 ATOM 4199 C C . PHE C 1 118 ? 0.905 -4.027 55.674 1.00 21.86 ? 118 PHE C C 1 ATOM 4200 O O . PHE C 1 118 ? -0.023 -3.410 55.154 1.00 20.03 ? 118 PHE C O 1 ATOM 4201 C CB . PHE C 1 118 ? 2.000 -4.812 53.619 1.00 15.41 ? 118 PHE C CB 1 ATOM 4202 C CG . PHE C 1 118 ? 2.610 -5.899 52.790 1.00 21.59 ? 118 PHE C CG 1 ATOM 4203 C CD1 . PHE C 1 118 ? 3.902 -6.357 53.048 1.00 21.97 ? 118 PHE C CD1 1 ATOM 4204 C CD2 . PHE C 1 118 ? 1.916 -6.433 51.715 1.00 21.50 ? 118 PHE C CD2 1 ATOM 4205 C CE1 . PHE C 1 118 ? 4.483 -7.353 52.264 1.00 17.38 ? 118 PHE C CE1 1 ATOM 4206 C CE2 . PHE C 1 118 ? 2.483 -7.424 50.923 1.00 20.51 ? 118 PHE C CE2 1 ATOM 4207 C CZ . PHE C 1 118 ? 3.773 -7.888 51.201 1.00 23.07 ? 118 PHE C CZ 1 ATOM 4208 N N . PRO C 1 119 ? 1.453 -3.643 56.829 1.00 22.21 ? 119 PRO C N 1 ATOM 4209 C CA . PRO C 1 119 ? 0.942 -2.480 57.555 1.00 20.81 ? 119 PRO C CA 1 ATOM 4210 C C . PRO C 1 119 ? 1.355 -1.244 56.813 1.00 22.91 ? 119 PRO C C 1 ATOM 4211 O O . PRO C 1 119 ? 2.310 -1.320 56.059 1.00 23.52 ? 119 PRO C O 1 ATOM 4212 C CB . PRO C 1 119 ? 1.701 -2.534 58.891 1.00 21.70 ? 119 PRO C CB 1 ATOM 4213 C CG . PRO C 1 119 ? 2.338 -3.893 58.942 1.00 28.11 ? 119 PRO C CG 1 ATOM 4214 C CD . PRO C 1 119 ? 2.586 -4.271 57.523 1.00 26.09 ? 119 PRO C CD 1 ATOM 4215 N N . PRO C 1 120 ? 0.660 -0.120 57.027 1.00 25.74 ? 120 PRO C N 1 ATOM 4216 C CA . PRO C 1 120 ? 1.083 1.156 56.443 1.00 22.53 ? 120 PRO C CA 1 ATOM 4217 C C . PRO C 1 120 ? 2.481 1.508 56.923 1.00 20.91 ? 120 PRO C C 1 ATOM 4218 O O . PRO C 1 120 ? 2.859 1.113 58.015 1.00 23.37 ? 120 PRO C O 1 ATOM 4219 C CB . PRO C 1 120 ? 0.088 2.152 57.023 1.00 16.50 ? 120 PRO C CB 1 ATOM 4220 C CG . PRO C 1 120 ? -0.407 1.506 58.251 1.00 20.74 ? 120 PRO C CG 1 ATOM 4221 C CD . PRO C 1 120 ? -0.453 0.048 57.970 1.00 20.10 ? 120 PRO C CD 1 ATOM 4222 N N . SER C 1 121 ? 3.236 2.230 56.105 1.00 22.90 ? 121 SER C N 1 ATOM 4223 C CA . SER C 1 121 ? 4.582 2.633 56.471 1.00 26.67 ? 121 SER C CA 1 ATOM 4224 C C . SER C 1 121 ? 4.456 3.864 57.335 1.00 25.20 ? 121 SER C C 1 ATOM 4225 O O . SER C 1 121 ? 3.436 4.552 57.286 1.00 26.66 ? 121 SER C O 1 ATOM 4226 C CB . SER C 1 121 ? 5.394 2.972 55.220 1.00 21.13 ? 121 SER C CB 1 ATOM 4227 O OG . SER C 1 121 ? 4.921 4.174 54.634 1.00 18.60 ? 121 SER C OG 1 ATOM 4228 N N . ASP C 1 122 ? 5.487 4.134 58.127 1.00 26.01 ? 122 ASP C N 1 ATOM 4229 C CA . ASP C 1 122 ? 5.527 5.343 58.936 1.00 25.60 ? 122 ASP C CA 1 ATOM 4230 C C . ASP C 1 122 ? 5.634 6.571 58.049 1.00 26.13 ? 122 ASP C C 1 ATOM 4231 O O . ASP C 1 122 ? 5.129 7.638 58.398 1.00 28.99 ? 122 ASP C O 1 ATOM 4232 C CB . ASP C 1 122 ? 6.709 5.303 59.907 1.00 33.69 ? 122 ASP C CB 1 ATOM 4233 C CG . ASP C 1 122 ? 6.489 4.337 61.048 1.00 37.50 ? 122 ASP C CG 1 ATOM 4234 O OD1 . ASP C 1 122 ? 5.342 3.871 61.226 1.00 47.56 ? 122 ASP C OD1 1 ATOM 4235 O OD2 . ASP C 1 122 ? 7.458 4.052 61.778 1.00 42.73 ? 122 ASP C OD2 1 ATOM 4236 N N . GLU C 1 123 ? 6.294 6.420 56.901 1.00 26.29 ? 123 GLU C N 1 ATOM 4237 C CA A GLU C 1 123 ? 6.455 7.532 55.963 0.53 28.86 ? 123 GLU C CA 1 ATOM 4238 C CA B GLU C 1 123 ? 6.458 7.522 55.960 0.47 28.68 ? 123 GLU C CA 1 ATOM 4239 C C . GLU C 1 123 ? 5.107 7.994 55.410 1.00 27.40 ? 123 GLU C C 1 ATOM 4240 O O . GLU C 1 123 ? 4.873 9.197 55.239 1.00 23.79 ? 123 GLU C O 1 ATOM 4241 C CB A GLU C 1 123 ? 7.402 7.159 54.817 0.53 28.43 ? 123 GLU C CB 1 ATOM 4242 C CB B GLU C 1 123 ? 7.386 7.115 54.814 0.47 28.37 ? 123 GLU C CB 1 ATOM 4243 C CG A GLU C 1 123 ? 7.779 8.334 53.911 0.53 27.94 ? 123 GLU C CG 1 ATOM 4244 C CG B GLU C 1 123 ? 8.813 6.776 55.246 0.47 36.83 ? 123 GLU C CG 1 ATOM 4245 C CD A GLU C 1 123 ? 8.841 7.979 52.871 0.53 34.79 ? 123 GLU C CD 1 ATOM 4246 C CD B GLU C 1 123 ? 9.012 5.299 55.558 0.47 34.79 ? 123 GLU C CD 1 ATOM 4247 O OE1 A GLU C 1 123 ? 8.667 6.974 52.144 0.53 29.53 ? 123 GLU C OE1 1 ATOM 4248 O OE1 B GLU C 1 123 ? 8.526 4.829 56.613 0.47 32.64 ? 123 GLU C OE1 1 ATOM 4249 O OE2 A GLU C 1 123 ? 9.853 8.708 52.782 0.53 28.67 ? 123 GLU C OE2 1 ATOM 4250 O OE2 B GLU C 1 123 ? 9.665 4.611 54.744 0.47 27.91 ? 123 GLU C OE2 1 ATOM 4251 N N . GLN C 1 124 ? 4.214 7.045 55.140 1.00 19.59 ? 124 GLN C N 1 ATOM 4252 C CA . GLN C 1 124 ? 2.905 7.402 54.619 1.00 19.73 ? 124 GLN C CA 1 ATOM 4253 C C . GLN C 1 124 ? 2.060 8.085 55.686 1.00 22.24 ? 124 GLN C C 1 ATOM 4254 O O . GLN C 1 124 ? 1.347 9.043 55.392 1.00 21.66 ? 124 GLN C O 1 ATOM 4255 C CB . GLN C 1 124 ? 2.166 6.179 54.061 1.00 20.99 ? 124 GLN C CB 1 ATOM 4256 C CG . GLN C 1 124 ? 0.896 6.561 53.313 1.00 19.04 ? 124 GLN C CG 1 ATOM 4257 C CD . GLN C 1 124 ? -0.022 5.396 53.024 1.00 18.55 ? 124 GLN C CD 1 ATOM 4258 O OE1 . GLN C 1 124 ? 0.224 4.268 53.443 1.00 21.01 ? 124 GLN C OE1 1 ATOM 4259 N NE2 . GLN C 1 124 ? -1.099 5.671 52.307 1.00 23.19 ? 124 GLN C NE2 1 ATOM 4260 N N . LEU C 1 125 ? 2.146 7.592 56.922 1.00 21.43 ? 125 LEU C N 1 ATOM 4261 C CA . LEU C 1 125 ? 1.329 8.115 58.014 1.00 24.58 ? 125 LEU C CA 1 ATOM 4262 C C . LEU C 1 125 ? 1.456 9.635 58.201 1.00 30.10 ? 125 LEU C C 1 ATOM 4263 O O . LEU C 1 125 ? 0.483 10.298 58.575 1.00 32.19 ? 125 LEU C O 1 ATOM 4264 C CB . LEU C 1 125 ? 1.589 7.362 59.324 1.00 17.52 ? 125 LEU C CB 1 ATOM 4265 C CG . LEU C 1 125 ? 1.137 5.902 59.375 1.00 24.07 ? 125 LEU C CG 1 ATOM 4266 C CD1 . LEU C 1 125 ? 1.492 5.269 60.714 1.00 14.47 ? 125 LEU C CD1 1 ATOM 4267 C CD2 . LEU C 1 125 ? -0.359 5.755 59.088 1.00 18.02 ? 125 LEU C CD2 1 ATOM 4268 N N . LYS C 1 126 ? 2.633 10.187 57.906 1.00 33.31 ? 126 LYS C N 1 ATOM 4269 C CA . LYS C 1 126 ? 2.842 11.635 57.975 1.00 29.21 ? 126 LYS C CA 1 ATOM 4270 C C . LYS C 1 126 ? 1.911 12.380 57.020 1.00 28.62 ? 126 LYS C C 1 ATOM 4271 O O . LYS C 1 126 ? 1.688 13.581 57.169 1.00 36.33 ? 126 LYS C O 1 ATOM 4272 C CB . LYS C 1 126 ? 4.298 12.004 57.650 1.00 30.72 ? 126 LYS C CB 1 ATOM 4273 C CG . LYS C 1 126 ? 5.363 11.264 58.449 1.00 34.67 ? 126 LYS C CG 1 ATOM 4274 C CD . LYS C 1 126 ? 6.748 11.494 57.847 1.00 47.78 ? 126 LYS C CD 1 ATOM 4275 C CE . LYS C 1 126 ? 7.789 10.544 58.452 1.00 59.69 ? 126 LYS C CE 1 ATOM 4276 N NZ . LYS C 1 126 ? 9.114 10.614 57.758 1.00 59.46 ? 126 LYS C NZ 1 ATOM 4277 N N . SER C 1 127 ? 1.373 11.684 56.029 1.00 23.89 ? 127 SER C N 1 ATOM 4278 C CA . SER C 1 127 ? 0.508 12.364 55.076 1.00 33.38 ? 127 SER C CA 1 ATOM 4279 C C . SER C 1 127 ? -0.957 12.377 55.534 1.00 28.95 ? 127 SER C C 1 ATOM 4280 O O . SER C 1 127 ? -1.797 13.031 54.928 1.00 40.51 ? 127 SER C O 1 ATOM 4281 C CB . SER C 1 127 ? 0.673 11.793 53.654 1.00 27.43 ? 127 SER C CB 1 ATOM 4282 O OG . SER C 1 127 ? -0.019 10.568 53.467 1.00 30.53 ? 127 SER C OG 1 ATOM 4283 N N . GLY C 1 128 ? -1.257 11.667 56.615 1.00 24.24 ? 128 GLY C N 1 ATOM 4284 C CA . GLY C 1 128 ? -2.608 11.647 57.142 1.00 24.73 ? 128 GLY C CA 1 ATOM 4285 C C . GLY C 1 128 ? -3.472 10.530 56.580 1.00 28.55 ? 128 GLY C C 1 ATOM 4286 O O . GLY C 1 128 ? -4.672 10.483 56.840 1.00 24.92 ? 128 GLY C O 1 ATOM 4287 N N . THR C 1 129 ? -2.861 9.634 55.808 1.00 27.45 ? 129 THR C N 1 ATOM 4288 C CA . THR C 1 129 ? -3.554 8.485 55.239 1.00 22.61 ? 129 THR C CA 1 ATOM 4289 C C . THR C 1 129 ? -2.787 7.206 55.552 1.00 23.63 ? 129 THR C C 1 ATOM 4290 O O . THR C 1 129 ? -1.559 7.203 55.545 1.00 29.59 ? 129 THR C O 1 ATOM 4291 C CB . THR C 1 129 ? -3.733 8.639 53.694 1.00 27.79 ? 129 THR C CB 1 ATOM 4292 O OG1 . THR C 1 129 ? -4.836 9.510 53.410 1.00 28.68 ? 129 THR C OG1 1 ATOM 4293 C CG2 . THR C 1 129 ? -4.024 7.304 53.029 1.00 31.77 ? 129 THR C CG2 1 ATOM 4294 N N . ALA C 1 130 ? -3.503 6.126 55.837 1.00 16.64 ? 130 ALA C N 1 ATOM 4295 C CA . ALA C 1 130 ? -2.874 4.828 56.014 1.00 16.72 ? 130 ALA C CA 1 ATOM 4296 C C . ALA C 1 130 ? -3.405 3.856 54.985 1.00 20.95 ? 130 ALA C C 1 ATOM 4297 O O . ALA C 1 130 ? -4.606 3.607 54.943 1.00 20.54 ? 130 ALA C O 1 ATOM 4298 C CB . ALA C 1 130 ? -3.138 4.291 57.408 1.00 14.50 ? 130 ALA C CB 1 ATOM 4299 N N . SER C 1 131 ? -2.519 3.302 54.156 1.00 25.53 ? 131 SER C N 1 ATOM 4300 C CA . SER C 1 131 ? -2.904 2.220 53.249 1.00 14.77 ? 131 SER C CA 1 ATOM 4301 C C . SER C 1 131 ? -2.521 0.894 53.887 1.00 17.65 ? 131 SER C C 1 ATOM 4302 O O . SER C 1 131 ? -1.395 0.728 54.347 1.00 22.83 ? 131 SER C O 1 ATOM 4303 C CB . SER C 1 131 ? -2.223 2.365 51.884 1.00 14.05 ? 131 SER C CB 1 ATOM 4304 O OG . SER C 1 131 ? -2.539 3.593 51.241 1.00 10.50 ? 131 SER C OG 1 ATOM 4305 N N . VAL C 1 132 ? -3.459 -0.042 53.946 1.00 15.23 ? 132 VAL C N 1 ATOM 4306 C CA . VAL C 1 132 ? -3.146 -1.373 54.439 1.00 14.19 ? 132 VAL C CA 1 ATOM 4307 C C . VAL C 1 132 ? -3.383 -2.365 53.309 1.00 19.88 ? 132 VAL C C 1 ATOM 4308 O O . VAL C 1 132 ? -4.462 -2.380 52.713 1.00 19.31 ? 132 VAL C O 1 ATOM 4309 C CB . VAL C 1 132 ? -4.021 -1.759 55.640 1.00 18.05 ? 132 VAL C CB 1 ATOM 4310 C CG1 . VAL C 1 132 ? -3.552 -3.095 56.234 1.00 16.92 ? 132 VAL C CG1 1 ATOM 4311 C CG2 . VAL C 1 132 ? -4.008 -0.651 56.687 1.00 15.87 ? 132 VAL C CG2 1 ATOM 4312 N N . VAL C 1 133 ? -2.377 -3.186 53.012 1.00 18.36 ? 133 VAL C N 1 ATOM 4313 C CA . VAL C 1 133 ? -2.388 -3.978 51.795 1.00 15.67 ? 133 VAL C CA 1 ATOM 4314 C C . VAL C 1 133 ? -2.354 -5.475 52.051 1.00 18.54 ? 133 VAL C C 1 ATOM 4315 O O . VAL C 1 133 ? -1.588 -5.960 52.885 1.00 23.43 ? 133 VAL C O 1 ATOM 4316 C CB . VAL C 1 133 ? -1.218 -3.579 50.841 1.00 17.06 ? 133 VAL C CB 1 ATOM 4317 C CG1 . VAL C 1 133 ? -1.143 -4.507 49.619 1.00 7.65 ? 133 VAL C CG1 1 ATOM 4318 C CG2 . VAL C 1 133 ? -1.379 -2.151 50.398 1.00 16.26 ? 133 VAL C CG2 1 ATOM 4319 N N . CYS C 1 134 ? -3.185 -6.196 51.301 1.00 20.30 ? 134 CYS C N 1 ATOM 4320 C CA . CYS C 1 134 ? -3.281 -7.649 51.378 1.00 25.04 ? 134 CYS C CA 1 ATOM 4321 C C . CYS C 1 134 ? -2.925 -8.228 50.023 1.00 20.20 ? 134 CYS C C 1 ATOM 4322 O O . CYS C 1 134 ? -3.506 -7.842 49.017 1.00 20.24 ? 134 CYS C O 1 ATOM 4323 C CB . CYS C 1 134 ? -4.712 -8.051 51.743 1.00 23.41 ? 134 CYS C CB 1 ATOM 4324 S SG . CYS C 1 134 ? -4.961 -9.752 52.279 1.00 28.26 ? 134 CYS C SG 1 ATOM 4325 N N . LEU C 1 135 ? -1.965 -9.147 50.003 1.00 19.47 ? 135 LEU C N 1 ATOM 4326 C CA . LEU C 1 135 ? -1.541 -9.799 48.775 1.00 15.51 ? 135 LEU C CA 1 ATOM 4327 C C . LEU C 1 135 ? -2.066 -11.226 48.740 1.00 13.79 ? 135 LEU C C 1 ATOM 4328 O O . LEU C 1 135 ? -1.938 -11.967 49.708 1.00 20.16 ? 135 LEU C O 1 ATOM 4329 C CB . LEU C 1 135 ? -0.010 -9.815 48.682 1.00 11.87 ? 135 LEU C CB 1 ATOM 4330 C CG . LEU C 1 135 ? 0.640 -10.587 47.520 1.00 17.60 ? 135 LEU C CG 1 ATOM 4331 C CD1 . LEU C 1 135 ? 0.186 -10.038 46.157 1.00 15.84 ? 135 LEU C CD1 1 ATOM 4332 C CD2 . LEU C 1 135 ? 2.170 -10.574 47.618 1.00 12.62 ? 135 LEU C CD2 1 ATOM 4333 N N . LEU C 1 136 ? -2.665 -11.612 47.626 1.00 15.73 ? 136 LEU C N 1 ATOM 4334 C CA . LEU C 1 136 ? -2.982 -13.013 47.388 1.00 15.49 ? 136 LEU C CA 1 ATOM 4335 C C . LEU C 1 136 ? -2.132 -13.451 46.224 1.00 17.19 ? 136 LEU C C 1 ATOM 4336 O O . LEU C 1 136 ? -2.312 -12.967 45.108 1.00 17.05 ? 136 LEU C O 1 ATOM 4337 C CB . LEU C 1 136 ? -4.452 -13.194 47.039 1.00 16.20 ? 136 LEU C CB 1 ATOM 4338 C CG . LEU C 1 136 ? -5.498 -13.162 48.149 1.00 14.67 ? 136 LEU C CG 1 ATOM 4339 C CD1 . LEU C 1 136 ? -5.487 -11.876 48.973 1.00 12.48 ? 136 LEU C CD1 1 ATOM 4340 C CD2 . LEU C 1 136 ? -6.842 -13.355 47.492 1.00 19.33 ? 136 LEU C CD2 1 ATOM 4341 N N . ASN C 1 137 ? -1.197 -14.359 46.471 1.00 19.53 ? 137 ASN C N 1 ATOM 4342 C CA . ASN C 1 137 ? -0.237 -14.710 45.431 1.00 16.99 ? 137 ASN C CA 1 ATOM 4343 C C . ASN C 1 137 ? -0.521 -16.027 44.708 1.00 22.26 ? 137 ASN C C 1 ATOM 4344 O O . ASN C 1 137 ? -0.840 -17.040 45.335 1.00 21.66 ? 137 ASN C O 1 ATOM 4345 C CB . ASN C 1 137 ? 1.180 -14.727 45.988 1.00 19.08 ? 137 ASN C CB 1 ATOM 4346 C CG . ASN C 1 137 ? 2.192 -14.168 45.008 1.00 28.92 ? 137 ASN C CG 1 ATOM 4347 O OD1 . ASN C 1 137 ? 1.870 -13.294 44.198 1.00 22.82 ? 137 ASN C OD1 1 ATOM 4348 N ND2 . ASN C 1 137 ? 3.425 -14.666 45.079 1.00 22.35 ? 137 ASN C ND2 1 ATOM 4349 N N . ASN C 1 138 ? -0.420 -15.972 43.378 1.00 19.48 ? 138 ASN C N 1 ATOM 4350 C CA . ASN C 1 138 ? -0.329 -17.148 42.511 1.00 20.12 ? 138 ASN C CA 1 ATOM 4351 C C . ASN C 1 138 ? -1.416 -18.191 42.686 1.00 18.36 ? 138 ASN C C 1 ATOM 4352 O O . ASN C 1 138 ? -1.132 -19.308 43.098 1.00 21.28 ? 138 ASN C O 1 ATOM 4353 C CB . ASN C 1 138 ? 1.053 -17.813 42.655 1.00 20.62 ? 138 ASN C CB 1 ATOM 4354 C CG . ASN C 1 138 ? 2.190 -16.871 42.297 1.00 23.27 ? 138 ASN C CG 1 ATOM 4355 O OD1 . ASN C 1 138 ? 1.979 -15.848 41.656 1.00 22.62 ? 138 ASN C OD1 1 ATOM 4356 N ND2 . ASN C 1 138 ? 3.397 -17.211 42.715 1.00 27.87 ? 138 ASN C ND2 1 ATOM 4357 N N . PHE C 1 139 ? -2.649 -17.845 42.342 1.00 16.63 ? 139 PHE C N 1 ATOM 4358 C CA . PHE C 1 139 ? -3.776 -18.731 42.619 1.00 19.52 ? 139 PHE C CA 1 ATOM 4359 C C . PHE C 1 139 ? -4.620 -18.989 41.380 1.00 20.57 ? 139 PHE C C 1 ATOM 4360 O O . PHE C 1 139 ? -4.493 -18.294 40.372 1.00 20.19 ? 139 PHE C O 1 ATOM 4361 C CB . PHE C 1 139 ? -4.642 -18.169 43.761 1.00 20.04 ? 139 PHE C CB 1 ATOM 4362 C CG . PHE C 1 139 ? -5.174 -16.793 43.501 1.00 20.25 ? 139 PHE C CG 1 ATOM 4363 C CD1 . PHE C 1 139 ? -4.512 -15.678 43.985 1.00 20.03 ? 139 PHE C CD1 1 ATOM 4364 C CD2 . PHE C 1 139 ? -6.332 -16.611 42.764 1.00 20.95 ? 139 PHE C CD2 1 ATOM 4365 C CE1 . PHE C 1 139 ? -5.001 -14.404 43.744 1.00 18.63 ? 139 PHE C CE1 1 ATOM 4366 C CE2 . PHE C 1 139 ? -6.816 -15.349 42.514 1.00 17.72 ? 139 PHE C CE2 1 ATOM 4367 C CZ . PHE C 1 139 ? -6.150 -14.244 43.008 1.00 19.68 ? 139 PHE C CZ 1 ATOM 4368 N N . TYR C 1 140 ? -5.478 -19.998 41.460 1.00 19.12 ? 140 TYR C N 1 ATOM 4369 C CA . TYR C 1 140 ? -6.374 -20.324 40.357 1.00 19.47 ? 140 TYR C CA 1 ATOM 4370 C C . TYR C 1 140 ? -7.570 -21.095 40.903 1.00 23.97 ? 140 TYR C C 1 ATOM 4371 O O . TYR C 1 140 ? -7.392 -22.044 41.674 1.00 21.92 ? 140 TYR C O 1 ATOM 4372 C CB . TYR C 1 140 ? -5.656 -21.140 39.275 1.00 15.71 ? 140 TYR C CB 1 ATOM 4373 C CG . TYR C 1 140 ? -6.508 -21.308 38.045 1.00 20.33 ? 140 TYR C CG 1 ATOM 4374 C CD1 . TYR C 1 140 ? -6.388 -20.439 36.968 1.00 19.67 ? 140 TYR C CD1 1 ATOM 4375 C CD2 . TYR C 1 140 ? -7.479 -22.299 37.981 1.00 18.77 ? 140 TYR C CD2 1 ATOM 4376 C CE1 . TYR C 1 140 ? -7.191 -20.572 35.855 1.00 17.71 ? 140 TYR C CE1 1 ATOM 4377 C CE2 . TYR C 1 140 ? -8.299 -22.429 36.887 1.00 15.97 ? 140 TYR C CE2 1 ATOM 4378 C CZ . TYR C 1 140 ? -8.148 -21.576 35.821 1.00 18.34 ? 140 TYR C CZ 1 ATOM 4379 O OH . TYR C 1 140 ? -8.964 -21.730 34.721 1.00 20.20 ? 140 TYR C OH 1 ATOM 4380 N N . PRO C 1 141 ? -8.788 -20.712 40.489 1.00 17.06 ? 141 PRO C N 1 ATOM 4381 C CA . PRO C 1 141 ? -9.114 -19.697 39.480 1.00 20.47 ? 141 PRO C CA 1 ATOM 4382 C C . PRO C 1 141 ? -9.142 -18.257 40.005 1.00 24.39 ? 141 PRO C C 1 ATOM 4383 O O . PRO C 1 141 ? -8.932 -17.999 41.197 1.00 21.71 ? 141 PRO C O 1 ATOM 4384 C CB . PRO C 1 141 ? -10.526 -20.088 39.065 1.00 22.13 ? 141 PRO C CB 1 ATOM 4385 C CG . PRO C 1 141 ? -11.130 -20.568 40.341 1.00 20.08 ? 141 PRO C CG 1 ATOM 4386 C CD . PRO C 1 141 ? -10.004 -21.323 41.049 1.00 19.16 ? 141 PRO C CD 1 ATOM 4387 N N . ARG C 1 142 ? -9.435 -17.341 39.087 1.00 19.93 ? 142 ARG C N 1 ATOM 4388 C CA . ARG C 1 142 ? -9.375 -15.904 39.315 1.00 25.69 ? 142 ARG C CA 1 ATOM 4389 C C . ARG C 1 142 ? -10.211 -15.421 40.507 1.00 28.06 ? 142 ARG C C 1 ATOM 4390 O O . ARG C 1 142 ? -9.768 -14.559 41.264 1.00 25.20 ? 142 ARG C O 1 ATOM 4391 C CB . ARG C 1 142 ? -9.837 -15.193 38.046 1.00 23.13 ? 142 ARG C CB 1 ATOM 4392 C CG . ARG C 1 142 ? -9.444 -13.737 37.917 1.00 33.41 ? 142 ARG C CG 1 ATOM 4393 C CD . ARG C 1 142 ? -10.007 -13.179 36.603 1.00 33.40 ? 142 ARG C CD 1 ATOM 4394 N NE . ARG C 1 142 ? -9.530 -11.833 36.300 1.00 33.56 ? 142 ARG C NE 1 ATOM 4395 C CZ . ARG C 1 142 ? -9.942 -10.733 36.925 1.00 57.36 ? 142 ARG C CZ 1 ATOM 4396 N NH1 . ARG C 1 142 ? -10.835 -10.814 37.905 1.00 54.02 ? 142 ARG C NH1 1 ATOM 4397 N NH2 . ARG C 1 142 ? -9.454 -9.548 36.577 1.00 53.39 ? 142 ARG C NH2 1 ATOM 4398 N N . GLU C 1 143 ? -11.407 -15.980 40.671 1.00 23.72 ? 143 GLU C N 1 ATOM 4399 C CA A GLU C 1 143 ? -12.340 -15.528 41.697 0.52 26.73 ? 143 GLU C CA 1 ATOM 4400 C CA B GLU C 1 143 ? -12.328 -15.508 41.702 0.48 26.53 ? 143 GLU C CA 1 ATOM 4401 C C . GLU C 1 143 ? -11.822 -15.756 43.116 1.00 23.46 ? 143 GLU C C 1 ATOM 4402 O O . GLU C 1 143 ? -11.448 -16.869 43.472 1.00 30.50 ? 143 GLU C O 1 ATOM 4403 C CB A GLU C 1 143 ? -13.701 -16.206 41.516 0.52 26.67 ? 143 GLU C CB 1 ATOM 4404 C CB B GLU C 1 143 ? -13.711 -16.136 41.537 0.48 26.67 ? 143 GLU C CB 1 ATOM 4405 C CG A GLU C 1 143 ? -14.445 -15.799 40.240 0.52 32.68 ? 143 GLU C CG 1 ATOM 4406 C CG B GLU C 1 143 ? -14.729 -15.673 42.584 0.48 30.93 ? 143 GLU C CG 1 ATOM 4407 C CD A GLU C 1 143 ? -13.877 -16.437 38.977 0.52 31.54 ? 143 GLU C CD 1 ATOM 4408 C CD B GLU C 1 143 ? -14.984 -14.170 42.533 0.48 35.66 ? 143 GLU C CD 1 ATOM 4409 O OE1 A GLU C 1 143 ? -13.173 -17.464 39.083 0.52 24.19 ? 143 GLU C OE1 1 ATOM 4410 O OE1 B GLU C 1 143 ? -15.378 -13.671 41.456 0.48 36.53 ? 143 GLU C OE1 1 ATOM 4411 O OE2 A GLU C 1 143 ? -14.138 -15.907 37.876 0.52 23.99 ? 143 GLU C OE2 1 ATOM 4412 O OE2 B GLU C 1 143 ? -14.781 -13.488 43.563 0.48 28.23 ? 143 GLU C OE2 1 ATOM 4413 N N . ALA C 1 144 ? -11.818 -14.697 43.916 1.00 22.66 ? 144 ALA C N 1 ATOM 4414 C CA . ALA C 1 144 ? -11.371 -14.763 45.301 1.00 25.10 ? 144 ALA C CA 1 ATOM 4415 C C . ALA C 1 144 ? -12.029 -13.635 46.082 1.00 25.91 ? 144 ALA C C 1 ATOM 4416 O O . ALA C 1 144 ? -12.330 -12.583 45.518 1.00 34.14 ? 144 ALA C O 1 ATOM 4417 C CB . ALA C 1 144 ? -9.860 -14.640 45.373 1.00 22.17 ? 144 ALA C CB 1 ATOM 4418 N N . LYS C 1 145 ? -12.264 -13.848 47.372 1.00 21.79 ? 145 LYS C N 1 ATOM 4419 C CA . LYS C 1 145 ? -12.836 -12.796 48.193 1.00 18.80 ? 145 LYS C CA 1 ATOM 4420 C C . LYS C 1 145 ? -11.905 -12.409 49.338 1.00 22.43 ? 145 LYS C C 1 ATOM 4421 O O . LYS C 1 145 ? -11.464 -13.252 50.116 1.00 23.64 ? 145 LYS C O 1 ATOM 4422 C CB . LYS C 1 145 ? -14.202 -13.212 48.719 1.00 20.67 ? 145 LYS C CB 1 ATOM 4423 C CG . LYS C 1 145 ? -15.037 -12.073 49.252 1.00 21.52 ? 145 LYS C CG 1 ATOM 4424 C CD . LYS C 1 145 ? -16.493 -12.501 49.455 1.00 26.19 ? 145 LYS C CD 1 ATOM 4425 C CE . LYS C 1 145 ? -17.229 -11.558 50.379 1.00 28.63 ? 145 LYS C CE 1 ATOM 4426 N NZ . LYS C 1 145 ? -18.695 -11.697 50.241 1.00 28.33 ? 145 LYS C NZ 1 ATOM 4427 N N . VAL C 1 146 ? -11.598 -11.121 49.414 1.00 25.10 ? 146 VAL C N 1 ATOM 4428 C CA . VAL C 1 146 ? -10.879 -10.547 50.534 1.00 17.27 ? 146 VAL C CA 1 ATOM 4429 C C . VAL C 1 146 ? -11.838 -9.722 51.376 1.00 18.92 ? 146 VAL C C 1 ATOM 4430 O O . VAL C 1 146 ? -12.496 -8.819 50.862 1.00 17.80 ? 146 VAL C O 1 ATOM 4431 C CB . VAL C 1 146 ? -9.790 -9.590 50.045 1.00 15.13 ? 146 VAL C CB 1 ATOM 4432 C CG1 . VAL C 1 146 ? -9.115 -8.894 51.235 1.00 17.56 ? 146 VAL C CG1 1 ATOM 4433 C CG2 . VAL C 1 146 ? -8.782 -10.338 49.200 1.00 19.32 ? 146 VAL C CG2 1 ATOM 4434 N N . GLN C 1 147 ? -11.916 -10.028 52.667 1.00 18.31 ? 147 GLN C N 1 ATOM 4435 C CA . GLN C 1 147 ? -12.634 -9.172 53.608 1.00 26.21 ? 147 GLN C CA 1 ATOM 4436 C C . GLN C 1 147 ? -11.674 -8.556 54.617 1.00 21.55 ? 147 GLN C C 1 ATOM 4437 O O . GLN C 1 147 ? -10.778 -9.232 55.115 1.00 23.53 ? 147 GLN C O 1 ATOM 4438 C CB . GLN C 1 147 ? -13.745 -9.951 54.328 1.00 19.89 ? 147 GLN C CB 1 ATOM 4439 C CG . GLN C 1 147 ? -14.832 -10.477 53.388 1.00 27.36 ? 147 GLN C CG 1 ATOM 4440 C CD . GLN C 1 147 ? -15.912 -11.266 54.104 1.00 31.88 ? 147 GLN C CD 1 ATOM 4441 O OE1 . GLN C 1 147 ? -15.626 -12.164 54.902 1.00 32.60 ? 147 GLN C OE1 1 ATOM 4442 N NE2 . GLN C 1 147 ? -17.167 -10.930 53.824 1.00 32.44 ? 147 GLN C NE2 1 ATOM 4443 N N . TRP C 1 148 ? -11.855 -7.269 54.897 1.00 22.38 ? 148 TRP C N 1 ATOM 4444 C CA . TRP C 1 148 ? -11.049 -6.566 55.898 1.00 21.33 ? 148 TRP C CA 1 ATOM 4445 C C . TRP C 1 148 ? -11.805 -6.413 57.210 1.00 17.49 ? 148 TRP C C 1 ATOM 4446 O O . TRP C 1 148 ? -12.898 -5.856 57.252 1.00 18.12 ? 148 TRP C O 1 ATOM 4447 C CB . TRP C 1 148 ? -10.638 -5.168 55.412 1.00 14.26 ? 148 TRP C CB 1 ATOM 4448 C CG . TRP C 1 148 ? -9.620 -5.164 54.317 1.00 22.55 ? 148 TRP C CG 1 ATOM 4449 C CD1 . TRP C 1 148 ? -9.862 -5.100 52.975 1.00 22.51 ? 148 TRP C CD1 1 ATOM 4450 C CD2 . TRP C 1 148 ? -8.197 -5.214 54.463 1.00 17.55 ? 148 TRP C CD2 1 ATOM 4451 N NE1 . TRP C 1 148 ? -8.683 -5.111 52.280 1.00 22.32 ? 148 TRP C NE1 1 ATOM 4452 C CE2 . TRP C 1 148 ? -7.643 -5.182 53.171 1.00 18.69 ? 148 TRP C CE2 1 ATOM 4453 C CE3 . TRP C 1 148 ? -7.339 -5.292 55.558 1.00 15.23 ? 148 TRP C CE3 1 ATOM 4454 C CZ2 . TRP C 1 148 ? -6.270 -5.232 52.942 1.00 17.10 ? 148 TRP C CZ2 1 ATOM 4455 C CZ3 . TRP C 1 148 ? -5.987 -5.328 55.332 1.00 20.77 ? 148 TRP C CZ3 1 ATOM 4456 C CH2 . TRP C 1 148 ? -5.461 -5.303 54.031 1.00 16.83 ? 148 TRP C CH2 1 ATOM 4457 N N . LYS C 1 149 ? -11.218 -6.908 58.286 1.00 21.89 ? 149 LYS C N 1 ATOM 4458 C CA . LYS C 1 149 ? -11.779 -6.665 59.604 1.00 25.83 ? 149 LYS C CA 1 ATOM 4459 C C . LYS C 1 149 ? -10.785 -5.856 60.421 1.00 22.47 ? 149 LYS C C 1 ATOM 4460 O O . LYS C 1 149 ? -9.620 -6.212 60.510 1.00 27.83 ? 149 LYS C O 1 ATOM 4461 C CB . LYS C 1 149 ? -12.151 -7.980 60.293 1.00 20.18 ? 149 LYS C CB 1 ATOM 4462 C CG . LYS C 1 149 ? -12.895 -8.935 59.376 1.00 21.67 ? 149 LYS C CG 1 ATOM 4463 C CD . LYS C 1 149 ? -13.799 -9.908 60.127 1.00 20.86 ? 149 LYS C CD 1 ATOM 4464 C CE . LYS C 1 149 ? -14.521 -10.818 59.133 1.00 33.02 ? 149 LYS C CE 1 ATOM 4465 N NZ . LYS C 1 149 ? -14.899 -12.147 59.705 1.00 37.20 ? 149 LYS C NZ 1 ATOM 4466 N N . VAL C 1 150 ? -11.249 -4.747 60.976 1.00 20.70 ? 150 VAL C N 1 ATOM 4467 C CA . VAL C 1 150 ? -10.449 -3.919 61.858 1.00 20.54 ? 150 VAL C CA 1 ATOM 4468 C C . VAL C 1 150 ? -11.058 -3.969 63.252 1.00 22.67 ? 150 VAL C C 1 ATOM 4469 O O . VAL C 1 150 ? -12.195 -3.524 63.443 1.00 23.74 ? 150 VAL C O 1 ATOM 4470 C CB . VAL C 1 150 ? -10.475 -2.468 61.389 1.00 18.75 ? 150 VAL C CB 1 ATOM 4471 C CG1 . VAL C 1 150 ? -9.637 -1.612 62.318 1.00 15.71 ? 150 VAL C CG1 1 ATOM 4472 C CG2 . VAL C 1 150 ? -9.999 -2.373 59.957 1.00 19.50 ? 150 VAL C CG2 1 ATOM 4473 N N . ASP C 1 151 ? -10.318 -4.512 64.218 1.00 28.45 ? 151 ASP C N 1 ATOM 4474 C CA . ASP C 1 151 ? -10.872 -4.782 65.558 1.00 25.85 ? 151 ASP C CA 1 ATOM 4475 C C . ASP C 1 151 ? -12.219 -5.502 65.440 1.00 26.07 ? 151 ASP C C 1 ATOM 4476 O O . ASP C 1 151 ? -13.174 -5.190 66.142 1.00 26.95 ? 151 ASP C O 1 ATOM 4477 C CB . ASP C 1 151 ? -11.005 -3.494 66.383 1.00 25.26 ? 151 ASP C CB 1 ATOM 4478 C CG . ASP C 1 151 ? -9.680 -3.026 66.968 1.00 22.15 ? 151 ASP C CG 1 ATOM 4479 O OD1 . ASP C 1 151 ? -8.776 -3.863 67.137 1.00 28.30 ? 151 ASP C OD1 1 ATOM 4480 O OD2 . ASP C 1 151 ? -9.546 -1.826 67.276 1.00 26.63 ? 151 ASP C OD2 1 ATOM 4481 N N . ASN C 1 152 ? -12.268 -6.438 64.498 1.00 25.76 ? 152 ASN C N 1 ATOM 4482 C CA . ASN C 1 152 ? -13.429 -7.278 64.211 1.00 25.76 ? 152 ASN C CA 1 ATOM 4483 C C . ASN C 1 152 ? -14.637 -6.637 63.536 1.00 27.96 ? 152 ASN C C 1 ATOM 4484 O O . ASN C 1 152 ? -15.665 -7.299 63.356 1.00 24.30 ? 152 ASN C O 1 ATOM 4485 C CB . ASN C 1 152 ? -13.854 -8.110 65.424 1.00 31.11 ? 152 ASN C CB 1 ATOM 4486 C CG . ASN C 1 152 ? -13.304 -9.518 65.363 1.00 48.64 ? 152 ASN C CG 1 ATOM 4487 O OD1 . ASN C 1 152 ? -13.676 -10.308 64.483 1.00 47.97 ? 152 ASN C OD1 1 ATOM 4488 N ND2 . ASN C 1 152 ? -12.396 -9.837 66.280 1.00 45.72 ? 152 ASN C ND2 1 ATOM 4489 N N . ALA C 1 153 ? -14.526 -5.370 63.150 1.00 19.39 ? 153 ALA C N 1 ATOM 4490 C CA . ALA C 1 153 ? -15.580 -4.780 62.346 1.00 19.90 ? 153 ALA C CA 1 ATOM 4491 C C . ALA C 1 153 ? -15.276 -5.043 60.870 1.00 22.58 ? 153 ALA C C 1 ATOM 4492 O O . ALA C 1 153 ? -14.178 -4.752 60.401 1.00 16.68 ? 153 ALA C O 1 ATOM 4493 C CB . ALA C 1 153 ? -15.712 -3.276 62.627 1.00 14.16 ? 153 ALA C CB 1 ATOM 4494 N N . LEU C 1 154 ? -16.236 -5.622 60.153 1.00 19.28 ? 154 LEU C N 1 ATOM 4495 C CA . LEU C 1 154 ? -16.115 -5.770 58.711 1.00 16.10 ? 154 LEU C CA 1 ATOM 4496 C C . LEU C 1 154 ? -16.034 -4.395 58.069 1.00 21.64 ? 154 LEU C C 1 ATOM 4497 O O . LEU C 1 154 ? -16.825 -3.506 58.389 1.00 26.42 ? 154 LEU C O 1 ATOM 4498 C CB . LEU C 1 154 ? -17.289 -6.558 58.130 1.00 18.07 ? 154 LEU C CB 1 ATOM 4499 C CG . LEU C 1 154 ? -17.331 -6.747 56.603 1.00 18.12 ? 154 LEU C CG 1 ATOM 4500 C CD1 . LEU C 1 154 ? -16.152 -7.590 56.093 1.00 22.10 ? 154 LEU C CD1 1 ATOM 4501 C CD2 . LEU C 1 154 ? -18.649 -7.366 56.140 1.00 15.35 ? 154 LEU C CD2 1 ATOM 4502 N N . GLN C 1 155 ? -15.064 -4.210 57.179 1.00 21.31 ? 155 GLN C N 1 ATOM 4503 C CA . GLN C 1 155 ? -14.955 -2.960 56.437 1.00 19.02 ? 155 GLN C CA 1 ATOM 4504 C C . GLN C 1 155 ? -15.730 -3.063 55.129 1.00 25.61 ? 155 GLN C C 1 ATOM 4505 O O . GLN C 1 155 ? -15.782 -4.121 54.487 1.00 22.88 ? 155 GLN C O 1 ATOM 4506 C CB . GLN C 1 155 ? -13.495 -2.625 56.157 1.00 18.42 ? 155 GLN C CB 1 ATOM 4507 C CG . GLN C 1 155 ? -12.635 -2.575 57.414 1.00 14.20 ? 155 GLN C CG 1 ATOM 4508 C CD . GLN C 1 155 ? -13.001 -1.424 58.323 1.00 15.45 ? 155 GLN C CD 1 ATOM 4509 O OE1 . GLN C 1 155 ? -12.971 -0.265 57.921 1.00 16.09 ? 155 GLN C OE1 1 ATOM 4510 N NE2 . GLN C 1 155 ? -13.337 -1.738 59.566 1.00 23.21 ? 155 GLN C NE2 1 ATOM 4511 N N . SER C 1 156 ? -16.358 -1.962 54.750 1.00 21.43 ? 156 SER C N 1 ATOM 4512 C CA . SER C 1 156 ? -17.064 -1.905 53.499 1.00 17.18 ? 156 SER C CA 1 ATOM 4513 C C . SER C 1 156 ? -16.916 -0.521 52.910 1.00 21.41 ? 156 SER C C 1 ATOM 4514 O O . SER C 1 156 ? -17.083 0.480 53.608 1.00 21.01 ? 156 SER C O 1 ATOM 4515 C CB . SER C 1 156 ? -18.534 -2.224 53.702 1.00 14.16 ? 156 SER C CB 1 ATOM 4516 O OG . SER C 1 156 ? -19.199 -2.325 52.443 1.00 16.09 ? 156 SER C OG 1 ATOM 4517 N N . GLY C 1 157 ? -16.582 -0.471 51.627 1.00 19.93 ? 157 GLY C N 1 ATOM 4518 C CA . GLY C 1 157 ? -16.539 0.783 50.907 1.00 18.06 ? 157 GLY C CA 1 ATOM 4519 C C . GLY C 1 157 ? -15.195 1.484 50.944 1.00 16.99 ? 157 GLY C C 1 ATOM 4520 O O . GLY C 1 157 ? -15.028 2.504 50.277 1.00 21.96 ? 157 GLY C O 1 ATOM 4521 N N . ASN C 1 158 ? -14.253 0.964 51.733 1.00 16.61 ? 158 ASN C N 1 ATOM 4522 C CA . ASN C 1 158 ? -12.920 1.554 51.824 1.00 17.60 ? 158 ASN C CA 1 ATOM 4523 C C . ASN C 1 158 ? -11.786 0.636 51.337 1.00 20.99 ? 158 ASN C C 1 ATOM 4524 O O . ASN C 1 158 ? -10.636 0.725 51.801 1.00 19.52 ? 158 ASN C O 1 ATOM 4525 C CB . ASN C 1 158 ? -12.642 2.088 53.224 1.00 12.14 ? 158 ASN C CB 1 ATOM 4526 C CG . ASN C 1 158 ? -12.822 1.040 54.304 1.00 20.43 ? 158 ASN C CG 1 ATOM 4527 O OD1 . ASN C 1 158 ? -13.041 -0.138 54.019 1.00 21.53 ? 158 ASN C OD1 1 ATOM 4528 N ND2 . ASN C 1 158 ? -12.722 1.467 55.567 1.00 16.84 ? 158 ASN C ND2 1 ATOM 4529 N N . SER C 1 159 ? -12.105 -0.235 50.391 1.00 13.47 ? 159 SER C N 1 ATOM 4530 C CA . SER C 1 159 ? -11.078 -1.062 49.789 1.00 21.47 ? 159 SER C CA 1 ATOM 4531 C C . SER C 1 159 ? -11.180 -1.151 48.254 1.00 18.39 ? 159 SER C C 1 ATOM 4532 O O . SER C 1 159 ? -12.271 -1.086 47.661 1.00 15.48 ? 159 SER C O 1 ATOM 4533 C CB . SER C 1 159 ? -11.064 -2.454 50.435 1.00 15.72 ? 159 SER C CB 1 ATOM 4534 O OG . SER C 1 159 ? -12.327 -3.074 50.303 1.00 22.87 ? 159 SER C OG 1 ATOM 4535 N N . GLN C 1 160 ? -10.021 -1.267 47.621 1.00 17.73 ? 160 GLN C N 1 ATOM 4536 C CA . GLN C 1 160 ? -9.944 -1.491 46.171 1.00 21.78 ? 160 GLN C CA 1 ATOM 4537 C C . GLN C 1 160 ? -9.070 -2.719 45.872 1.00 17.04 ? 160 GLN C C 1 ATOM 4538 O O . GLN C 1 160 ? -8.040 -2.927 46.501 1.00 20.48 ? 160 GLN C O 1 ATOM 4539 C CB . GLN C 1 160 ? -9.414 -0.245 45.444 1.00 16.91 ? 160 GLN C CB 1 ATOM 4540 C CG . GLN C 1 160 ? -10.346 0.956 45.494 1.00 17.01 ? 160 GLN C CG 1 ATOM 4541 C CD . GLN C 1 160 ? -9.975 2.063 44.489 1.00 32.47 ? 160 GLN C CD 1 ATOM 4542 O OE1 . GLN C 1 160 ? -9.033 2.832 44.712 1.00 27.23 ? 160 GLN C OE1 1 ATOM 4543 N NE2 . GLN C 1 160 ? -10.728 2.147 43.385 1.00 17.53 ? 160 GLN C NE2 1 ATOM 4544 N N . GLU C 1 161 ? -9.513 -3.555 44.946 1.00 15.39 ? 161 GLU C N 1 ATOM 4545 C CA . GLU C 1 161 ? -8.748 -4.737 44.565 1.00 19.58 ? 161 GLU C CA 1 ATOM 4546 C C . GLU C 1 161 ? -8.163 -4.516 43.187 1.00 24.30 ? 161 GLU C C 1 ATOM 4547 O O . GLU C 1 161 ? -8.590 -3.623 42.451 1.00 21.88 ? 161 GLU C O 1 ATOM 4548 C CB . GLU C 1 161 ? -9.631 -5.985 44.519 1.00 18.58 ? 161 GLU C CB 1 ATOM 4549 C CG . GLU C 1 161 ? -10.201 -6.455 45.853 1.00 32.15 ? 161 GLU C CG 1 ATOM 4550 C CD . GLU C 1 161 ? -11.010 -7.728 45.682 1.00 37.49 ? 161 GLU C CD 1 ATOM 4551 O OE1 . GLU C 1 161 ? -11.162 -8.157 44.513 1.00 32.27 ? 161 GLU C OE1 1 ATOM 4552 O OE2 . GLU C 1 161 ? -11.489 -8.299 46.697 1.00 38.47 ? 161 GLU C OE2 1 ATOM 4553 N N . SER C 1 162 ? -7.194 -5.347 42.832 1.00 23.28 ? 162 SER C N 1 ATOM 4554 C CA . SER C 1 162 ? -6.576 -5.279 41.521 1.00 17.48 ? 162 SER C CA 1 ATOM 4555 C C . SER C 1 162 ? -6.023 -6.657 41.210 1.00 18.34 ? 162 SER C C 1 ATOM 4556 O O . SER C 1 162 ? -5.383 -7.279 42.057 1.00 21.00 ? 162 SER C O 1 ATOM 4557 C CB . SER C 1 162 ? -5.475 -4.230 41.514 1.00 17.17 ? 162 SER C CB 1 ATOM 4558 O OG . SER C 1 162 ? -4.864 -4.133 40.247 1.00 24.07 ? 162 SER C OG 1 ATOM 4559 N N . VAL C 1 163 ? -6.310 -7.157 40.015 1.00 15.21 ? 163 VAL C N 1 ATOM 4560 C CA . VAL C 1 163 ? -5.885 -8.501 39.647 1.00 21.88 ? 163 VAL C CA 1 ATOM 4561 C C . VAL C 1 163 ? -4.983 -8.451 38.432 1.00 19.56 ? 163 VAL C C 1 ATOM 4562 O O . VAL C 1 163 ? -5.274 -7.741 37.472 1.00 21.21 ? 163 VAL C O 1 ATOM 4563 C CB . VAL C 1 163 ? -7.079 -9.419 39.345 1.00 21.83 ? 163 VAL C CB 1 ATOM 4564 C CG1 . VAL C 1 163 ? -6.596 -10.822 39.027 1.00 25.83 ? 163 VAL C CG1 1 ATOM 4565 C CG2 . VAL C 1 163 ? -8.017 -9.442 40.516 1.00 23.22 ? 163 VAL C CG2 1 ATOM 4566 N N . THR C 1 164 ? -3.876 -9.186 38.487 1.00 19.96 ? 164 THR C N 1 ATOM 4567 C CA . THR C 1 164 ? -2.974 -9.295 37.346 1.00 20.18 ? 164 THR C CA 1 ATOM 4568 C C . THR C 1 164 ? -3.650 -10.066 36.223 1.00 22.03 ? 164 THR C C 1 ATOM 4569 O O . THR C 1 164 ? -4.648 -10.753 36.434 1.00 26.42 ? 164 THR C O 1 ATOM 4570 C CB . THR C 1 164 ? -1.698 -10.032 37.726 1.00 15.18 ? 164 THR C CB 1 ATOM 4571 O OG1 . THR C 1 164 ? -2.039 -11.224 38.429 1.00 20.47 ? 164 THR C OG1 1 ATOM 4572 C CG2 . THR C 1 164 ? -0.828 -9.169 38.627 1.00 18.62 ? 164 THR C CG2 1 ATOM 4573 N N . GLU C 1 165 ? -3.123 -9.955 35.017 1.00 24.85 ? 165 GLU C N 1 ATOM 4574 C CA . GLU C 1 165 ? -3.561 -10.856 33.957 1.00 28.84 ? 165 GLU C CA 1 ATOM 4575 C C . GLU C 1 165 ? -3.005 -12.240 34.251 1.00 23.98 ? 165 GLU C C 1 ATOM 4576 O O . GLU C 1 165 ? -2.113 -12.389 35.072 1.00 22.45 ? 165 GLU C O 1 ATOM 4577 C CB . GLU C 1 165 ? -3.099 -10.361 32.582 1.00 23.71 ? 165 GLU C CB 1 ATOM 4578 C CG . GLU C 1 165 ? -3.907 -9.150 32.083 1.00 35.16 ? 165 GLU C CG 1 ATOM 4579 C CD . GLU C 1 165 ? -5.401 -9.454 31.923 1.00 33.68 ? 165 GLU C CD 1 ATOM 4580 O OE1 . GLU C 1 165 ? -5.756 -10.625 31.664 1.00 39.01 ? 165 GLU C OE1 1 ATOM 4581 O OE2 . GLU C 1 165 ? -6.224 -8.523 32.059 1.00 37.95 ? 165 GLU C OE2 1 ATOM 4582 N N . GLN C 1 166 ? -3.535 -13.259 33.597 1.00 30.34 ? 166 GLN C N 1 ATOM 4583 C CA . GLN C 1 166 ? -3.055 -14.604 33.862 1.00 26.67 ? 166 GLN C CA 1 ATOM 4584 C C . GLN C 1 166 ? -1.574 -14.736 33.504 1.00 28.10 ? 166 GLN C C 1 ATOM 4585 O O . GLN C 1 166 ? -1.120 -14.223 32.485 1.00 27.02 ? 166 GLN C O 1 ATOM 4586 C CB . GLN C 1 166 ? -3.892 -15.625 33.115 1.00 22.87 ? 166 GLN C CB 1 ATOM 4587 C CG . GLN C 1 166 ? -3.809 -16.989 33.723 1.00 30.16 ? 166 GLN C CG 1 ATOM 4588 C CD . GLN C 1 166 ? -4.648 -17.986 32.976 1.00 25.52 ? 166 GLN C CD 1 ATOM 4589 O OE1 . GLN C 1 166 ? -5.130 -17.703 31.881 1.00 28.88 ? 166 GLN C OE1 1 ATOM 4590 N NE2 . GLN C 1 166 ? -4.824 -19.165 33.557 1.00 22.35 ? 166 GLN C NE2 1 ATOM 4591 N N . ASP C 1 167 ? -0.830 -15.417 34.364 1.00 28.92 ? 167 ASP C N 1 ATOM 4592 C CA . ASP C 1 167 ? 0.624 -15.461 34.280 1.00 27.55 ? 167 ASP C CA 1 ATOM 4593 C C . ASP C 1 167 ? 1.146 -16.418 33.194 1.00 20.92 ? 167 ASP C C 1 ATOM 4594 O O . ASP C 1 167 ? 0.706 -17.549 33.094 1.00 28.37 ? 167 ASP C O 1 ATOM 4595 C CB . ASP C 1 167 ? 1.183 -15.834 35.656 1.00 32.13 ? 167 ASP C CB 1 ATOM 4596 C CG . ASP C 1 167 ? 2.682 -15.658 35.744 1.00 31.31 ? 167 ASP C CG 1 ATOM 4597 O OD1 . ASP C 1 167 ? 3.403 -16.624 35.402 1.00 26.23 ? 167 ASP C OD1 1 ATOM 4598 O OD2 . ASP C 1 167 ? 3.129 -14.561 36.163 1.00 32.90 ? 167 ASP C OD2 1 ATOM 4599 N N . SER C 1 168 ? 2.098 -15.980 32.386 1.00 26.30 ? 168 SER C N 1 ATOM 4600 C CA . SER C 1 168 ? 2.451 -16.777 31.210 1.00 26.45 ? 168 SER C CA 1 ATOM 4601 C C . SER C 1 168 ? 3.302 -17.995 31.522 1.00 29.99 ? 168 SER C C 1 ATOM 4602 O O . SER C 1 168 ? 3.513 -18.832 30.648 1.00 30.90 ? 168 SER C O 1 ATOM 4603 C CB . SER C 1 168 ? 3.077 -15.934 30.084 1.00 24.09 ? 168 SER C CB 1 ATOM 4604 O OG . SER C 1 168 ? 4.194 -15.196 30.528 1.00 23.12 ? 168 SER C OG 1 ATOM 4605 N N . LYS C 1 169 ? 3.770 -18.123 32.761 1.00 25.92 ? 169 LYS C N 1 ATOM 4606 C CA . LYS C 1 169 ? 4.525 -19.322 33.117 1.00 26.53 ? 169 LYS C CA 1 ATOM 4607 C C . LYS C 1 169 ? 3.650 -20.406 33.747 1.00 28.30 ? 169 LYS C C 1 ATOM 4608 O O . LYS C 1 169 ? 3.627 -21.536 33.257 1.00 30.31 ? 169 LYS C O 1 ATOM 4609 C CB . LYS C 1 169 ? 5.749 -18.992 33.985 1.00 22.17 ? 169 LYS C CB 1 ATOM 4610 N N . ASP C 1 170 ? 2.908 -20.056 34.800 1.00 26.41 ? 170 ASP C N 1 ATOM 4611 C CA . ASP C 1 170 ? 2.174 -21.051 35.602 1.00 22.06 ? 170 ASP C CA 1 ATOM 4612 C C . ASP C 1 170 ? 0.655 -20.912 35.563 1.00 19.44 ? 170 ASP C C 1 ATOM 4613 O O . ASP C 1 170 ? -0.053 -21.657 36.235 1.00 17.64 ? 170 ASP C O 1 ATOM 4614 C CB . ASP C 1 170 ? 2.643 -21.025 37.062 1.00 19.12 ? 170 ASP C CB 1 ATOM 4615 C CG . ASP C 1 170 ? 2.445 -19.655 37.732 1.00 32.48 ? 170 ASP C CG 1 ATOM 4616 O OD1 . ASP C 1 170 ? 1.717 -18.791 37.186 1.00 26.67 ? 170 ASP C OD1 1 ATOM 4617 O OD2 . ASP C 1 170 ? 3.033 -19.438 38.816 1.00 34.59 ? 170 ASP C OD2 1 ATOM 4618 N N . SER C 1 171 ? 0.176 -19.931 34.806 1.00 20.70 ? 171 SER C N 1 ATOM 4619 C CA . SER C 1 171 ? -1.260 -19.708 34.575 1.00 23.43 ? 171 SER C CA 1 ATOM 4620 C C . SER C 1 171 ? -2.079 -19.270 35.801 1.00 24.63 ? 171 SER C C 1 ATOM 4621 O O . SER C 1 171 ? -3.304 -19.405 35.804 1.00 18.36 ? 171 SER C O 1 ATOM 4622 C CB . SER C 1 171 ? -1.909 -20.930 33.918 1.00 16.61 ? 171 SER C CB 1 ATOM 4623 O OG . SER C 1 171 ? -1.281 -21.230 32.692 1.00 22.68 ? 171 SER C OG 1 ATOM 4624 N N . THR C 1 172 ? -1.417 -18.735 36.822 1.00 14.78 ? 172 THR C N 1 ATOM 4625 C CA . THR C 1 172 ? -2.127 -18.242 37.988 1.00 18.59 ? 172 THR C CA 1 ATOM 4626 C C . THR C 1 172 ? -2.385 -16.744 37.938 1.00 21.46 ? 172 THR C C 1 ATOM 4627 O O . THR C 1 172 ? -1.858 -16.030 37.081 1.00 27.37 ? 172 THR C O 1 ATOM 4628 C CB . THR C 1 172 ? -1.353 -18.512 39.276 1.00 18.87 ? 172 THR C CB 1 ATOM 4629 O OG1 . THR C 1 172 ? -0.179 -17.692 39.303 1.00 19.00 ? 172 THR C OG1 1 ATOM 4630 C CG2 . THR C 1 172 ? -0.990 -19.977 39.394 1.00 15.99 ? 172 THR C CG2 1 ATOM 4631 N N . TYR C 1 173 ? -3.191 -16.278 38.884 1.00 17.36 ? 173 TYR C N 1 ATOM 4632 C CA . TYR C 1 173 ? -3.449 -14.859 39.059 1.00 19.65 ? 173 TYR C CA 1 ATOM 4633 C C . TYR C 1 173 ? -2.870 -14.432 40.384 1.00 20.42 ? 173 TYR C C 1 ATOM 4634 O O . TYR C 1 173 ? -2.662 -15.261 41.271 1.00 22.23 ? 173 TYR C O 1 ATOM 4635 C CB . TYR C 1 173 ? -4.959 -14.576 39.066 1.00 20.22 ? 173 TYR C CB 1 ATOM 4636 C CG . TYR C 1 173 ? -5.655 -15.001 37.808 1.00 22.16 ? 173 TYR C CG 1 ATOM 4637 C CD1 . TYR C 1 173 ? -5.833 -14.107 36.758 1.00 25.85 ? 173 TYR C CD1 1 ATOM 4638 C CD2 . TYR C 1 173 ? -6.116 -16.304 37.653 1.00 23.24 ? 173 TYR C CD2 1 ATOM 4639 C CE1 . TYR C 1 173 ? -6.464 -14.493 35.580 1.00 22.08 ? 173 TYR C CE1 1 ATOM 4640 C CE2 . TYR C 1 173 ? -6.747 -16.708 36.486 1.00 27.06 ? 173 TYR C CE2 1 ATOM 4641 C CZ . TYR C 1 173 ? -6.922 -15.794 35.450 1.00 28.51 ? 173 TYR C CZ 1 ATOM 4642 O OH . TYR C 1 173 ? -7.541 -16.183 34.290 1.00 31.31 ? 173 TYR C OH 1 ATOM 4643 N N . SER C 1 174 ? -2.614 -13.137 40.522 1.00 20.00 ? 174 SER C N 1 ATOM 4644 C CA . SER C 1 174 ? -2.357 -12.570 41.835 1.00 16.53 ? 174 SER C CA 1 ATOM 4645 C C . SER C 1 174 ? -3.302 -11.393 42.056 1.00 19.08 ? 174 SER C C 1 ATOM 4646 O O . SER C 1 174 ? -3.752 -10.762 41.097 1.00 24.36 ? 174 SER C O 1 ATOM 4647 C CB . SER C 1 174 ? -0.887 -12.174 41.991 1.00 18.44 ? 174 SER C CB 1 ATOM 4648 O OG . SER C 1 174 ? -0.071 -13.333 42.080 1.00 17.13 ? 174 SER C OG 1 ATOM 4649 N N . LEU C 1 175 ? -3.629 -11.125 43.314 1.00 18.52 ? 175 LEU C N 1 ATOM 4650 C CA . LEU C 1 175 ? -4.520 -10.024 43.675 1.00 17.65 ? 175 LEU C CA 1 ATOM 4651 C C . LEU C 1 175 ? -3.931 -9.223 44.843 1.00 19.62 ? 175 LEU C C 1 ATOM 4652 O O . LEU C 1 175 ? -3.315 -9.764 45.761 1.00 13.80 ? 175 LEU C O 1 ATOM 4653 C CB . LEU C 1 175 ? -5.921 -10.549 44.024 1.00 12.95 ? 175 LEU C CB 1 ATOM 4654 C CG . LEU C 1 175 ? -7.058 -9.610 44.490 1.00 22.44 ? 175 LEU C CG 1 ATOM 4655 C CD1 . LEU C 1 175 ? -8.442 -10.251 44.261 1.00 12.12 ? 175 LEU C CD1 1 ATOM 4656 C CD2 . LEU C 1 175 ? -6.933 -9.205 45.946 1.00 12.83 ? 175 LEU C CD2 1 ATOM 4657 N N . SER C 1 176 ? -4.132 -7.918 44.796 1.00 19.47 ? 176 SER C N 1 ATOM 4658 C CA . SER C 1 176 ? -3.799 -7.085 45.919 1.00 20.06 ? 176 SER C CA 1 ATOM 4659 C C . SER C 1 176 ? -5.031 -6.279 46.301 1.00 20.28 ? 176 SER C C 1 ATOM 4660 O O . SER C 1 176 ? -5.681 -5.679 45.448 1.00 20.93 ? 176 SER C O 1 ATOM 4661 C CB . SER C 1 176 ? -2.645 -6.165 45.575 1.00 15.25 ? 176 SER C CB 1 ATOM 4662 O OG . SER C 1 176 ? -3.105 -5.148 44.729 1.00 27.89 ? 176 SER C OG 1 ATOM 4663 N N . SER C 1 177 ? -5.346 -6.283 47.590 1.00 17.96 ? 177 SER C N 1 ATOM 4664 C CA . SER C 1 177 ? -6.441 -5.500 48.136 1.00 18.80 ? 177 SER C CA 1 ATOM 4665 C C . SER C 1 177 ? -5.823 -4.392 48.978 1.00 18.89 ? 177 SER C C 1 ATOM 4666 O O . SER C 1 177 ? -4.927 -4.644 49.781 1.00 19.85 ? 177 SER C O 1 ATOM 4667 C CB . SER C 1 177 ? -7.350 -6.408 48.981 1.00 19.87 ? 177 SER C CB 1 ATOM 4668 O OG . SER C 1 177 ? -8.490 -5.731 49.473 1.00 19.75 ? 177 SER C OG 1 ATOM 4669 N N . THR C 1 178 ? -6.267 -3.161 48.753 1.00 20.35 ? 178 THR C N 1 ATOM 4670 C CA . THR C 1 178 ? -5.791 -2.014 49.516 1.00 14.29 ? 178 THR C CA 1 ATOM 4671 C C . THR C 1 178 ? -6.921 -1.406 50.333 1.00 17.52 ? 178 THR C C 1 ATOM 4672 O O . THR C 1 178 ? -7.898 -0.899 49.772 1.00 14.21 ? 178 THR C O 1 ATOM 4673 C CB . THR C 1 178 ? -5.236 -0.908 48.620 1.00 9.85 ? 178 THR C CB 1 ATOM 4674 O OG1 . THR C 1 178 ? -4.107 -1.397 47.903 1.00 21.89 ? 178 THR C OG1 1 ATOM 4675 C CG2 . THR C 1 178 ? -4.803 0.282 49.462 1.00 15.41 ? 178 THR C CG2 1 ATOM 4676 N N . LEU C 1 179 ? -6.765 -1.449 51.655 1.00 15.93 ? 179 LEU C N 1 ATOM 4677 C CA . LEU C 1 179 ? -7.681 -0.796 52.585 1.00 13.98 ? 179 LEU C CA 1 ATOM 4678 C C . LEU C 1 179 ? -7.167 0.609 52.854 1.00 14.28 ? 179 LEU C C 1 ATOM 4679 O O . LEU C 1 179 ? -6.030 0.777 53.292 1.00 18.71 ? 179 LEU C O 1 ATOM 4680 C CB . LEU C 1 179 ? -7.740 -1.592 53.896 1.00 13.37 ? 179 LEU C CB 1 ATOM 4681 C CG . LEU C 1 179 ? -8.648 -1.076 55.015 1.00 15.75 ? 179 LEU C CG 1 ATOM 4682 C CD1 . LEU C 1 179 ? -10.102 -1.439 54.728 1.00 17.54 ? 179 LEU C CD1 1 ATOM 4683 C CD2 . LEU C 1 179 ? -8.201 -1.580 56.388 1.00 12.46 ? 179 LEU C CD2 1 ATOM 4684 N N . THR C 1 180 ? -7.978 1.614 52.539 1.00 18.29 ? 180 THR C N 1 ATOM 4685 C CA . THR C 1 180 ? -7.592 3.004 52.780 1.00 15.19 ? 180 THR C CA 1 ATOM 4686 C C . THR C 1 180 ? -8.331 3.575 53.973 1.00 19.33 ? 180 THR C C 1 ATOM 4687 O O . THR C 1 180 ? -9.553 3.443 54.096 1.00 27.03 ? 180 THR C O 1 ATOM 4688 C CB . THR C 1 180 ? -7.795 3.900 51.547 1.00 15.87 ? 180 THR C CB 1 ATOM 4689 O OG1 . THR C 1 180 ? -7.059 3.363 50.438 1.00 25.44 ? 180 THR C OG1 1 ATOM 4690 C CG2 . THR C 1 180 ? -7.279 5.308 51.834 1.00 11.24 ? 180 THR C CG2 1 ATOM 4691 N N . LEU C 1 181 ? -7.597 4.164 54.880 1.00 18.26 ? 181 LEU C N 1 ATOM 4692 C CA . LEU C 1 181 ? -8.070 4.668 56.141 1.00 18.83 ? 181 LEU C CA 1 ATOM 4693 C C . LEU C 1 181 ? -7.402 5.961 56.444 1.00 19.44 ? 181 LEU C C 1 ATOM 4694 O O . LEU C 1 181 ? -6.314 6.171 56.078 1.00 19.48 ? 181 LEU C O 1 ATOM 4695 C CB . LEU C 1 181 ? -7.703 3.721 57.258 1.00 18.24 ? 181 LEU C CB 1 ATOM 4696 C CG . LEU C 1 181 ? -8.349 2.404 57.571 1.00 28.83 ? 181 LEU C CG 1 ATOM 4697 C CD1 . LEU C 1 181 ? -7.652 1.715 58.715 1.00 24.06 ? 181 LEU C CD1 1 ATOM 4698 C CD2 . LEU C 1 181 ? -9.810 2.554 57.873 1.00 30.14 ? 181 LEU C CD2 1 ATOM 4699 N N . SER C 1 182 ? -8.053 6.819 57.191 1.00 23.91 ? 182 SER C N 1 ATOM 4700 C CA . SER C 1 182 ? -7.416 8.061 57.631 1.00 23.66 ? 182 SER C CA 1 ATOM 4701 C C . SER C 1 182 ? -6.391 7.708 58.707 1.00 24.51 ? 182 SER C C 1 ATOM 4702 O O . SER C 1 182 ? -6.518 6.676 59.381 1.00 20.80 ? 182 SER C O 1 ATOM 4703 C CB . SER C 1 182 ? -8.454 9.041 58.167 1.00 19.75 ? 182 SER C CB 1 ATOM 4704 O OG . SER C 1 182 ? -9.056 8.558 59.339 1.00 30.23 ? 182 SER C OG 1 ATOM 4705 N N . LYS C 1 183 ? -5.366 8.538 58.857 1.00 22.21 ? 183 LYS C N 1 ATOM 4706 C CA . LYS C 1 183 ? -4.382 8.319 59.922 1.00 26.76 ? 183 LYS C CA 1 ATOM 4707 C C . LYS C 1 183 ? -5.057 8.224 61.299 1.00 29.64 ? 183 LYS C C 1 ATOM 4708 O O . LYS C 1 183 ? -4.683 7.398 62.133 1.00 22.15 ? 183 LYS C O 1 ATOM 4709 C CB . LYS C 1 183 ? -3.320 9.421 59.939 1.00 28.45 ? 183 LYS C CB 1 ATOM 4710 C CG . LYS C 1 183 ? -2.200 9.172 60.951 1.00 26.49 ? 183 LYS C CG 1 ATOM 4711 C CD . LYS C 1 183 ? -1.414 10.444 61.276 1.00 33.11 ? 183 LYS C CD 1 ATOM 4712 C CE . LYS C 1 183 ? -0.356 10.182 62.357 1.00 41.26 ? 183 LYS C CE 1 ATOM 4713 N NZ . LYS C 1 183 ? -0.054 11.386 63.205 1.00 43.61 ? 183 LYS C NZ 1 ATOM 4714 N N . ALA C 1 184 ? -6.069 9.058 61.520 1.00 24.78 ? 184 ALA C N 1 ATOM 4715 C CA . ALA C 1 184 ? -6.765 9.084 62.803 1.00 28.64 ? 184 ALA C CA 1 ATOM 4716 C C . ALA C 1 184 ? -7.486 7.765 63.092 1.00 32.09 ? 184 ALA C C 1 ATOM 4717 O O . ALA C 1 184 ? -7.361 7.211 64.187 1.00 25.75 ? 184 ALA C O 1 ATOM 4718 C CB . ALA C 1 184 ? -7.747 10.260 62.862 1.00 22.05 ? 184 ALA C CB 1 ATOM 4719 N N . ASP C 1 185 ? -8.244 7.277 62.110 1.00 30.67 ? 185 ASP C N 1 ATOM 4720 C CA . ASP C 1 185 ? -8.955 6.021 62.259 1.00 25.46 ? 185 ASP C CA 1 ATOM 4721 C C . ASP C 1 185 ? -7.964 4.894 62.505 1.00 24.56 ? 185 ASP C C 1 ATOM 4722 O O . ASP C 1 185 ? -8.190 4.037 63.359 1.00 24.00 ? 185 ASP C O 1 ATOM 4723 C CB . ASP C 1 185 ? -9.818 5.722 61.020 1.00 33.96 ? 185 ASP C CB 1 ATOM 4724 C CG . ASP C 1 185 ? -11.177 6.412 61.070 1.00 37.48 ? 185 ASP C CG 1 ATOM 4725 O OD1 . ASP C 1 185 ? -11.539 6.942 62.149 1.00 40.56 ? 185 ASP C OD1 1 ATOM 4726 O OD2 . ASP C 1 185 ? -11.889 6.407 60.037 1.00 35.97 ? 185 ASP C OD2 1 ATOM 4727 N N . TYR C 1 186 ? -6.866 4.906 61.754 1.00 21.10 ? 186 TYR C N 1 ATOM 4728 C CA . TYR C 1 186 ? -5.869 3.854 61.867 1.00 21.16 ? 186 TYR C CA 1 ATOM 4729 C C . TYR C 1 186 ? -5.296 3.811 63.280 1.00 23.05 ? 186 TYR C C 1 ATOM 4730 O O . TYR C 1 186 ? -5.101 2.734 63.840 1.00 22.93 ? 186 TYR C O 1 ATOM 4731 C CB . TYR C 1 186 ? -4.750 4.029 60.831 1.00 20.12 ? 186 TYR C CB 1 ATOM 4732 C CG . TYR C 1 186 ? -3.628 3.032 60.990 1.00 20.78 ? 186 TYR C CG 1 ATOM 4733 C CD1 . TYR C 1 186 ? -3.811 1.690 60.676 1.00 21.82 ? 186 TYR C CD1 1 ATOM 4734 C CD2 . TYR C 1 186 ? -2.379 3.428 61.461 1.00 24.25 ? 186 TYR C CD2 1 ATOM 4735 C CE1 . TYR C 1 186 ? -2.773 0.763 60.834 1.00 18.57 ? 186 TYR C CE1 1 ATOM 4736 C CE2 . TYR C 1 186 ? -1.335 2.510 61.614 1.00 18.82 ? 186 TYR C CE2 1 ATOM 4737 C CZ . TYR C 1 186 ? -1.542 1.187 61.303 1.00 19.32 ? 186 TYR C CZ 1 ATOM 4738 O OH . TYR C 1 186 ? -0.511 0.293 61.461 1.00 22.92 ? 186 TYR C OH 1 ATOM 4739 N N . GLU C 1 187 ? -5.046 4.987 63.853 1.00 27.92 ? 187 GLU C N 1 ATOM 4740 C CA . GLU C 1 187 ? -4.484 5.097 65.200 1.00 24.47 ? 187 GLU C CA 1 ATOM 4741 C C . GLU C 1 187 ? -5.451 4.680 66.306 1.00 24.16 ? 187 GLU C C 1 ATOM 4742 O O . GLU C 1 187 ? -5.030 4.343 67.399 1.00 32.81 ? 187 GLU C O 1 ATOM 4743 C CB . GLU C 1 187 ? -3.977 6.517 65.471 1.00 27.18 ? 187 GLU C CB 1 ATOM 4744 C CG . GLU C 1 187 ? -2.786 6.956 64.630 1.00 32.55 ? 187 GLU C CG 1 ATOM 4745 C CD . GLU C 1 187 ? -1.541 6.093 64.826 1.00 40.96 ? 187 GLU C CD 1 ATOM 4746 O OE1 . GLU C 1 187 ? -1.462 5.347 65.832 1.00 38.30 ? 187 GLU C OE1 1 ATOM 4747 O OE2 . GLU C 1 187 ? -0.634 6.157 63.961 1.00 42.32 ? 187 GLU C OE2 1 ATOM 4748 N N . LYS C 1 188 ? -6.744 4.702 66.025 1.00 24.32 ? 188 LYS C N 1 ATOM 4749 C CA . LYS C 1 188 ? -7.744 4.337 67.031 1.00 28.05 ? 188 LYS C CA 1 ATOM 4750 C C . LYS C 1 188 ? -7.987 2.836 67.171 1.00 26.83 ? 188 LYS C C 1 ATOM 4751 O O . LYS C 1 188 ? -8.763 2.410 68.017 1.00 27.98 ? 188 LYS C O 1 ATOM 4752 C CB . LYS C 1 188 ? -9.078 5.038 66.746 1.00 27.20 ? 188 LYS C CB 1 ATOM 4753 C CG . LYS C 1 188 ? -9.078 6.511 67.107 1.00 33.67 ? 188 LYS C CG 1 ATOM 4754 C CD . LYS C 1 188 ? -10.391 7.193 66.746 1.00 36.95 ? 188 LYS C CD 1 ATOM 4755 C CE . LYS C 1 188 ? -10.376 8.675 67.136 1.00 39.76 ? 188 LYS C CE 1 ATOM 4756 N NZ . LYS C 1 188 ? -9.465 9.511 66.288 1.00 28.77 ? 188 LYS C NZ 1 ATOM 4757 N N . HIS C 1 189 ? -7.335 2.030 66.347 1.00 26.44 ? 189 HIS C N 1 ATOM 4758 C CA . HIS C 1 189 ? -7.636 0.604 66.341 1.00 24.12 ? 189 HIS C CA 1 ATOM 4759 C C . HIS C 1 189 ? -6.384 -0.255 66.433 1.00 23.95 ? 189 HIS C C 1 ATOM 4760 O O . HIS C 1 189 ? -5.273 0.237 66.240 1.00 24.26 ? 189 HIS C O 1 ATOM 4761 C CB . HIS C 1 189 ? -8.479 0.256 65.117 1.00 23.17 ? 189 HIS C CB 1 ATOM 4762 C CG . HIS C 1 189 ? -9.834 0.889 65.133 1.00 31.07 ? 189 HIS C CG 1 ATOM 4763 N ND1 . HIS C 1 189 ? -10.176 1.947 64.320 1.00 36.44 ? 189 HIS C ND1 1 ATOM 4764 C CD2 . HIS C 1 189 ? -10.931 0.628 65.890 1.00 27.66 ? 189 HIS C CD2 1 ATOM 4765 C CE1 . HIS C 1 189 ? -11.426 2.301 64.563 1.00 29.28 ? 189 HIS C CE1 1 ATOM 4766 N NE2 . HIS C 1 189 ? -11.903 1.517 65.514 1.00 27.96 ? 189 HIS C NE2 1 ATOM 4767 N N . LYS C 1 190 ? -6.560 -1.533 66.733 1.00 19.25 ? 190 LYS C N 1 ATOM 4768 C CA . LYS C 1 190 ? -5.408 -2.368 67.026 1.00 25.53 ? 190 LYS C CA 1 ATOM 4769 C C . LYS C 1 190 ? -5.198 -3.510 66.050 1.00 20.90 ? 190 LYS C C 1 ATOM 4770 O O . LYS C 1 190 ? -4.109 -3.663 65.499 1.00 28.50 ? 190 LYS C O 1 ATOM 4771 C CB . LYS C 1 190 ? -5.479 -2.927 68.457 1.00 30.10 ? 190 LYS C CB 1 ATOM 4772 C CG . LYS C 1 190 ? -4.153 -3.525 68.937 1.00 31.35 ? 190 LYS C CG 1 ATOM 4773 C CD . LYS C 1 190 ? -4.281 -4.316 70.231 1.00 44.03 ? 190 LYS C CD 1 ATOM 4774 C CE . LYS C 1 190 ? -2.931 -4.907 70.637 1.00 45.58 ? 190 LYS C CE 1 ATOM 4775 N NZ . LYS C 1 190 ? -2.965 -5.548 71.982 1.00 47.19 ? 190 LYS C NZ 1 ATOM 4776 N N . VAL C 1 191 ? -6.219 -4.332 65.863 1.00 17.17 ? 191 VAL C N 1 ATOM 4777 C CA . VAL C 1 191 ? -6.061 -5.552 65.090 1.00 19.64 ? 191 VAL C CA 1 ATOM 4778 C C . VAL C 1 191 ? -6.516 -5.399 63.651 1.00 22.81 ? 191 VAL C C 1 ATOM 4779 O O . VAL C 1 191 ? -7.706 -5.235 63.384 1.00 22.93 ? 191 VAL C O 1 ATOM 4780 C CB . VAL C 1 191 ? -6.863 -6.710 65.700 1.00 21.83 ? 191 VAL C CB 1 ATOM 4781 C CG1 . VAL C 1 191 ? -6.673 -7.973 64.861 1.00 16.21 ? 191 VAL C CG1 1 ATOM 4782 C CG2 . VAL C 1 191 ? -6.452 -6.940 67.139 1.00 23.20 ? 191 VAL C CG2 1 ATOM 4783 N N . TYR C 1 192 ? -5.570 -5.495 62.725 1.00 19.54 ? 192 TYR C N 1 ATOM 4784 C CA . TYR C 1 192 ? -5.876 -5.434 61.304 1.00 17.70 ? 192 TYR C CA 1 ATOM 4785 C C . TYR C 1 192 ? -5.796 -6.813 60.657 1.00 18.02 ? 192 TYR C C 1 ATOM 4786 O O . TYR C 1 192 ? -4.887 -7.589 60.914 1.00 20.96 ? 192 TYR C O 1 ATOM 4787 C CB . TYR C 1 192 ? -4.974 -4.408 60.618 1.00 15.87 ? 192 TYR C CB 1 ATOM 4788 C CG . TYR C 1 192 ? -5.281 -3.032 61.122 1.00 19.17 ? 192 TYR C CG 1 ATOM 4789 C CD1 . TYR C 1 192 ? -6.217 -2.236 60.480 1.00 15.00 ? 192 TYR C CD1 1 ATOM 4790 C CD2 . TYR C 1 192 ? -4.686 -2.549 62.287 1.00 20.23 ? 192 TYR C CD2 1 ATOM 4791 C CE1 . TYR C 1 192 ? -6.520 -0.983 60.949 1.00 19.58 ? 192 TYR C CE1 1 ATOM 4792 C CE2 . TYR C 1 192 ? -4.992 -1.303 62.772 1.00 21.74 ? 192 TYR C CE2 1 ATOM 4793 C CZ . TYR C 1 192 ? -5.915 -0.522 62.102 1.00 23.03 ? 192 TYR C CZ 1 ATOM 4794 O OH . TYR C 1 192 ? -6.230 0.730 62.579 1.00 23.64 ? 192 TYR C OH 1 ATOM 4795 N N . ALA C 1 193 ? -6.769 -7.126 59.821 1.00 18.13 ? 193 ALA C N 1 ATOM 4796 C CA . ALA C 1 193 ? -6.878 -8.475 59.296 1.00 16.85 ? 193 ALA C CA 1 ATOM 4797 C C . ALA C 1 193 ? -7.450 -8.484 57.903 1.00 20.69 ? 193 ALA C C 1 ATOM 4798 O O . ALA C 1 193 ? -8.315 -7.674 57.555 1.00 23.44 ? 193 ALA C O 1 ATOM 4799 C CB . ALA C 1 193 ? -7.749 -9.333 60.218 1.00 11.53 ? 193 ALA C CB 1 ATOM 4800 N N . CYS C 1 194 ? -6.973 -9.410 57.096 1.00 16.55 ? 194 CYS C N 1 ATOM 4801 C CA . CYS C 1 194 ? -7.676 -9.687 55.864 1.00 23.84 ? 194 CYS C CA 1 ATOM 4802 C C . CYS C 1 194 ? -7.974 -11.164 55.823 1.00 19.16 ? 194 CYS C C 1 ATOM 4803 O O . CYS C 1 194 ? -7.104 -11.997 56.073 1.00 24.77 ? 194 CYS C O 1 ATOM 4804 C CB . CYS C 1 194 ? -6.910 -9.211 54.617 1.00 27.95 ? 194 CYS C CB 1 ATOM 4805 S SG . CYS C 1 194 ? -5.373 -10.074 54.250 1.00 33.10 ? 194 CYS C SG 1 ATOM 4806 N N . GLU C 1 195 ? -9.227 -11.476 55.535 1.00 21.27 ? 195 GLU C N 1 ATOM 4807 C CA . GLU C 1 195 ? -9.670 -12.848 55.467 1.00 22.82 ? 195 GLU C CA 1 ATOM 4808 C C . GLU C 1 195 ? -9.838 -13.174 54.008 1.00 19.84 ? 195 GLU C C 1 ATOM 4809 O O . GLU C 1 195 ? -10.290 -12.343 53.221 1.00 26.82 ? 195 GLU C O 1 ATOM 4810 C CB . GLU C 1 195 ? -10.997 -12.997 56.194 1.00 25.44 ? 195 GLU C CB 1 ATOM 4811 C CG . GLU C 1 195 ? -11.358 -14.416 56.525 1.00 29.59 ? 195 GLU C CG 1 ATOM 4812 C CD . GLU C 1 195 ? -12.667 -14.500 57.293 1.00 38.29 ? 195 GLU C CD 1 ATOM 4813 O OE1 . GLU C 1 195 ? -13.157 -13.434 57.740 1.00 33.03 ? 195 GLU C OE1 1 ATOM 4814 O OE2 . GLU C 1 195 ? -13.205 -15.623 57.442 1.00 36.53 ? 195 GLU C OE2 1 ATOM 4815 N N . VAL C 1 196 ? -9.474 -14.384 53.634 1.00 18.29 ? 196 VAL C N 1 ATOM 4816 C CA . VAL C 1 196 ? -9.511 -14.735 52.237 1.00 16.89 ? 196 VAL C CA 1 ATOM 4817 C C . VAL C 1 196 ? -10.319 -16.005 52.038 1.00 20.32 ? 196 VAL C C 1 ATOM 4818 O O . VAL C 1 196 ? -10.094 -17.011 52.713 1.00 25.33 ? 196 VAL C O 1 ATOM 4819 C CB . VAL C 1 196 ? -8.080 -14.902 51.659 1.00 19.25 ? 196 VAL C CB 1 ATOM 4820 C CG1 . VAL C 1 196 ? -8.139 -15.243 50.182 1.00 19.14 ? 196 VAL C CG1 1 ATOM 4821 C CG2 . VAL C 1 196 ? -7.249 -13.632 51.881 1.00 11.57 ? 196 VAL C CG2 1 ATOM 4822 N N . THR C 1 197 ? -11.265 -15.961 51.109 1.00 19.67 ? 197 THR C N 1 ATOM 4823 C CA . THR C 1 197 ? -11.969 -17.168 50.705 1.00 20.75 ? 197 THR C CA 1 ATOM 4824 C C . THR C 1 197 ? -11.695 -17.419 49.230 1.00 21.47 ? 197 THR C C 1 ATOM 4825 O O . THR C 1 197 ? -11.629 -16.490 48.436 1.00 27.41 ? 197 THR C O 1 ATOM 4826 C CB . THR C 1 197 ? -13.492 -17.055 50.957 1.00 18.22 ? 197 THR C CB 1 ATOM 4827 O OG1 . THR C 1 197 ? -14.005 -15.942 50.221 1.00 24.72 ? 197 THR C OG1 1 ATOM 4828 C CG2 . THR C 1 197 ? -13.761 -16.840 52.414 1.00 17.13 ? 197 THR C CG2 1 ATOM 4829 N N . HIS C 1 198 ? -11.529 -18.682 48.874 1.00 22.58 ? 198 HIS C N 1 ATOM 4830 C CA . HIS C 1 198 ? -11.191 -19.057 47.515 1.00 23.09 ? 198 HIS C CA 1 ATOM 4831 C C . HIS C 1 198 ? -11.469 -20.548 47.348 1.00 27.98 ? 198 HIS C C 1 ATOM 4832 O O . HIS C 1 198 ? -11.398 -21.307 48.316 1.00 24.00 ? 198 HIS C O 1 ATOM 4833 C CB . HIS C 1 198 ? -9.712 -18.749 47.243 1.00 23.68 ? 198 HIS C CB 1 ATOM 4834 C CG . HIS C 1 198 ? -9.230 -19.215 45.906 1.00 19.65 ? 198 HIS C CG 1 ATOM 4835 N ND1 . HIS C 1 198 ? -8.638 -20.442 45.719 1.00 19.20 ? 198 HIS C ND1 1 ATOM 4836 C CD2 . HIS C 1 198 ? -9.245 -18.617 44.689 1.00 21.48 ? 198 HIS C CD2 1 ATOM 4837 C CE1 . HIS C 1 198 ? -8.308 -20.583 44.446 1.00 21.69 ? 198 HIS C CE1 1 ATOM 4838 N NE2 . HIS C 1 198 ? -8.666 -19.488 43.799 1.00 19.77 ? 198 HIS C NE2 1 ATOM 4839 N N . GLN C 1 199 ? -11.790 -20.954 46.121 1.00 21.44 ? 199 GLN C N 1 ATOM 4840 C CA . GLN C 1 199 ? -12.069 -22.351 45.815 1.00 25.22 ? 199 GLN C CA 1 ATOM 4841 C C . GLN C 1 199 ? -11.024 -23.347 46.337 1.00 25.24 ? 199 GLN C C 1 ATOM 4842 O O . GLN C 1 199 ? -11.370 -24.429 46.802 1.00 31.70 ? 199 GLN C O 1 ATOM 4843 C CB . GLN C 1 199 ? -12.247 -22.540 44.316 1.00 24.20 ? 199 GLN C CB 1 ATOM 4844 C CG . GLN C 1 199 ? -12.537 -23.963 43.942 1.00 27.98 ? 199 GLN C CG 1 ATOM 4845 C CD . GLN C 1 199 ? -12.862 -24.096 42.485 1.00 35.68 ? 199 GLN C CD 1 ATOM 4846 O OE1 . GLN C 1 199 ? -13.191 -23.110 41.826 1.00 47.54 ? 199 GLN C OE1 1 ATOM 4847 N NE2 . GLN C 1 199 ? -12.764 -25.310 41.961 1.00 33.17 ? 199 GLN C NE2 1 ATOM 4848 N N . GLY C 1 200 ? -9.752 -22.978 46.262 1.00 23.68 ? 200 GLY C N 1 ATOM 4849 C CA . GLY C 1 200 ? -8.688 -23.805 46.790 1.00 17.78 ? 200 GLY C CA 1 ATOM 4850 C C . GLY C 1 200 ? -8.521 -23.728 48.296 1.00 21.72 ? 200 GLY C C 1 ATOM 4851 O O . GLY C 1 200 ? -7.570 -24.275 48.838 1.00 25.47 ? 200 GLY C O 1 ATOM 4852 N N . LEU C 1 201 ? -9.424 -23.045 48.986 1.00 24.66 ? 201 LEU C N 1 ATOM 4853 C CA . LEU C 1 201 ? -9.356 -23.041 50.455 1.00 31.01 ? 201 LEU C CA 1 ATOM 4854 C C . LEU C 1 201 ? -10.544 -23.769 51.114 1.00 27.73 ? 201 LEU C C 1 ATOM 4855 O O . LEU C 1 201 ? -11.707 -23.424 50.902 1.00 24.25 ? 201 LEU C O 1 ATOM 4856 C CB . LEU C 1 201 ? -9.195 -21.622 51.008 1.00 26.47 ? 201 LEU C CB 1 ATOM 4857 C CG . LEU C 1 201 ? -7.922 -20.887 50.585 1.00 25.43 ? 201 LEU C CG 1 ATOM 4858 C CD1 . LEU C 1 201 ? -7.969 -19.450 51.082 1.00 22.22 ? 201 LEU C CD1 1 ATOM 4859 C CD2 . LEU C 1 201 ? -6.664 -21.595 51.074 1.00 13.18 ? 201 LEU C CD2 1 ATOM 4860 N N . SER C 1 202 ? -10.228 -24.795 51.895 1.00 30.77 ? 202 SER C N 1 ATOM 4861 C CA . SER C 1 202 ? -11.240 -25.569 52.611 1.00 32.78 ? 202 SER C CA 1 ATOM 4862 C C . SER C 1 202 ? -11.922 -24.684 53.645 1.00 31.25 ? 202 SER C C 1 ATOM 4863 O O . SER C 1 202 ? -13.127 -24.763 53.837 1.00 37.75 ? 202 SER C O 1 ATOM 4864 C CB . SER C 1 202 ? -10.591 -26.763 53.304 1.00 31.07 ? 202 SER C CB 1 ATOM 4865 O OG . SER C 1 202 ? -9.444 -26.343 54.030 1.00 39.38 ? 202 SER C OG 1 ATOM 4866 N N . SER C 1 203 ? -11.135 -23.845 54.308 1.00 24.59 ? 203 SER C N 1 ATOM 4867 C CA . SER C 1 203 ? -11.658 -22.871 55.250 1.00 32.55 ? 203 SER C CA 1 ATOM 4868 C C . SER C 1 203 ? -10.882 -21.563 55.033 1.00 31.46 ? 203 SER C C 1 ATOM 4869 O O . SER C 1 203 ? -9.779 -21.599 54.489 1.00 31.67 ? 203 SER C O 1 ATOM 4870 C CB . SER C 1 203 ? -11.493 -23.399 56.677 1.00 29.30 ? 203 SER C CB 1 ATOM 4871 O OG . SER C 1 203 ? -10.263 -22.973 57.235 1.00 40.07 ? 203 SER C OG 1 ATOM 4872 N N . PRO C 1 204 ? -11.444 -20.405 55.449 1.00 29.35 ? 204 PRO C N 1 ATOM 4873 C CA . PRO C 1 204 ? -10.798 -19.129 55.109 1.00 16.14 ? 204 PRO C CA 1 ATOM 4874 C C . PRO C 1 204 ? -9.414 -18.996 55.710 1.00 19.76 ? 204 PRO C C 1 ATOM 4875 O O . PRO C 1 204 ? -9.105 -19.658 56.698 1.00 35.77 ? 204 PRO C O 1 ATOM 4876 C CB . PRO C 1 204 ? -11.711 -18.084 55.746 1.00 20.81 ? 204 PRO C CB 1 ATOM 4877 C CG . PRO C 1 204 ? -12.983 -18.791 56.055 1.00 31.70 ? 204 PRO C CG 1 ATOM 4878 C CD . PRO C 1 204 ? -12.608 -20.205 56.330 1.00 29.22 ? 204 PRO C CD 1 ATOM 4879 N N . VAL C 1 205 ? -8.579 -18.161 55.113 1.00 25.61 ? 205 VAL C N 1 ATOM 4880 C CA . VAL C 1 205 ? -7.266 -17.902 55.674 1.00 20.66 ? 205 VAL C CA 1 ATOM 4881 C C . VAL C 1 205 ? -7.179 -16.455 56.123 1.00 22.53 ? 205 VAL C C 1 ATOM 4882 O O . VAL C 1 205 ? -7.619 -15.555 55.417 1.00 24.19 ? 205 VAL C O 1 ATOM 4883 C CB . VAL C 1 205 ? -6.157 -18.234 54.674 1.00 23.27 ? 205 VAL C CB 1 ATOM 4884 C CG1 . VAL C 1 205 ? -4.830 -17.593 55.092 1.00 15.25 ? 205 VAL C CG1 1 ATOM 4885 C CG2 . VAL C 1 205 ? -6.042 -19.729 54.536 1.00 19.49 ? 205 VAL C CG2 1 ATOM 4886 N N . THR C 1 206 ? -6.653 -16.242 57.322 1.00 20.68 ? 206 THR C N 1 ATOM 4887 C CA . THR C 1 206 ? -6.570 -14.908 57.875 1.00 20.10 ? 206 THR C CA 1 ATOM 4888 C C . THR C 1 206 ? -5.114 -14.553 58.181 1.00 26.10 ? 206 THR C C 1 ATOM 4889 O O . THR C 1 206 ? -4.352 -15.371 58.695 1.00 18.91 ? 206 THR C O 1 ATOM 4890 C CB . THR C 1 206 ? -7.468 -14.771 59.129 1.00 20.06 ? 206 THR C CB 1 ATOM 4891 O OG1 . THR C 1 206 ? -8.814 -15.122 58.777 1.00 27.89 ? 206 THR C OG1 1 ATOM 4892 C CG2 . THR C 1 206 ? -7.451 -13.345 59.665 1.00 12.15 ? 206 THR C CG2 1 ATOM 4893 N N . LYS C 1 207 ? -4.734 -13.334 57.831 1.00 21.73 ? 207 LYS C N 1 ATOM 4894 C CA . LYS C 1 207 ? -3.409 -12.849 58.120 1.00 15.55 ? 207 LYS C CA 1 ATOM 4895 C C . LYS C 1 207 ? -3.644 -11.523 58.800 1.00 17.61 ? 207 LYS C C 1 ATOM 4896 O O . LYS C 1 207 ? -4.521 -10.776 58.387 1.00 22.53 ? 207 LYS C O 1 ATOM 4897 C CB . LYS C 1 207 ? -2.642 -12.657 56.814 1.00 16.28 ? 207 LYS C CB 1 ATOM 4898 C CG . LYS C 1 207 ? -1.382 -13.493 56.688 1.00 26.38 ? 207 LYS C CG 1 ATOM 4899 C CD . LYS C 1 207 ? -1.646 -14.997 56.657 1.00 26.25 ? 207 LYS C CD 1 ATOM 4900 C CE . LYS C 1 207 ? -0.320 -15.768 56.697 1.00 29.13 ? 207 LYS C CE 1 ATOM 4901 N NZ . LYS C 1 207 ? -0.514 -17.242 56.805 1.00 24.62 ? 207 LYS C NZ 1 ATOM 4902 N N . SER C 1 208 ? -2.889 -11.218 59.843 1.00 19.23 ? 208 SER C N 1 ATOM 4903 C CA . SER C 1 208 ? -3.138 -10.000 60.603 1.00 18.86 ? 208 SER C CA 1 ATOM 4904 C C . SER C 1 208 ? -1.876 -9.379 61.198 1.00 19.86 ? 208 SER C C 1 ATOM 4905 O O . SER C 1 208 ? -0.821 -9.989 61.218 1.00 30.26 ? 208 SER C O 1 ATOM 4906 C CB . SER C 1 208 ? -4.154 -10.282 61.723 1.00 19.74 ? 208 SER C CB 1 ATOM 4907 O OG . SER C 1 208 ? -3.848 -11.491 62.374 1.00 31.03 ? 208 SER C OG 1 ATOM 4908 N N . PHE C 1 209 ? -1.988 -8.154 61.683 1.00 14.59 ? 209 PHE C N 1 ATOM 4909 C CA . PHE C 1 209 ? -0.926 -7.563 62.453 1.00 23.35 ? 209 PHE C CA 1 ATOM 4910 C C . PHE C 1 209 ? -1.596 -6.693 63.490 1.00 26.85 ? 209 PHE C C 1 ATOM 4911 O O . PHE C 1 209 ? -2.734 -6.270 63.275 1.00 29.94 ? 209 PHE C O 1 ATOM 4912 C CB . PHE C 1 209 ? 0.037 -6.763 61.566 1.00 24.33 ? 209 PHE C CB 1 ATOM 4913 C CG . PHE C 1 209 ? -0.563 -5.505 60.974 1.00 27.78 ? 209 PHE C CG 1 ATOM 4914 C CD1 . PHE C 1 209 ? -1.133 -5.526 59.705 1.00 23.96 ? 209 PHE C CD1 1 ATOM 4915 C CD2 . PHE C 1 209 ? -0.529 -4.302 61.672 1.00 24.84 ? 209 PHE C CD2 1 ATOM 4916 C CE1 . PHE C 1 209 ? -1.669 -4.376 59.146 1.00 20.65 ? 209 PHE C CE1 1 ATOM 4917 C CE2 . PHE C 1 209 ? -1.067 -3.143 61.119 1.00 22.98 ? 209 PHE C CE2 1 ATOM 4918 C CZ . PHE C 1 209 ? -1.637 -3.184 59.854 1.00 23.40 ? 209 PHE C CZ 1 ATOM 4919 N N . ASN C 1 210 ? -0.924 -6.473 64.620 1.00 25.98 ? 210 ASN C N 1 ATOM 4920 C CA . ASN C 1 210 ? -1.355 -5.485 65.597 1.00 21.92 ? 210 ASN C CA 1 ATOM 4921 C C . ASN C 1 210 ? -0.578 -4.201 65.369 1.00 31.55 ? 210 ASN C C 1 ATOM 4922 O O . ASN C 1 210 ? 0.650 -4.219 65.353 1.00 33.36 ? 210 ASN C O 1 ATOM 4923 C CB . ASN C 1 210 ? -1.113 -5.988 67.016 1.00 28.64 ? 210 ASN C CB 1 ATOM 4924 C CG . ASN C 1 210 ? -1.917 -7.221 67.335 1.00 33.97 ? 210 ASN C CG 1 ATOM 4925 O OD1 . ASN C 1 210 ? -3.028 -7.404 66.830 1.00 34.24 ? 210 ASN C OD1 1 ATOM 4926 N ND2 . ASN C 1 210 ? -1.361 -8.084 68.172 1.00 26.60 ? 210 ASN C ND2 1 ATOM 4927 N N . ARG C 1 211 ? -1.291 -3.095 65.176 1.00 24.76 ? 211 ARG C N 1 ATOM 4928 C CA . ARG C 1 211 ? -0.652 -1.799 65.018 1.00 26.83 ? 211 ARG C CA 1 ATOM 4929 C C . ARG C 1 211 ? 0.263 -1.547 66.206 1.00 33.19 ? 211 ARG C C 1 ATOM 4930 O O . ARG C 1 211 ? -0.165 -1.669 67.346 1.00 27.92 ? 211 ARG C O 1 ATOM 4931 C CB . ARG C 1 211 ? -1.699 -0.689 64.929 1.00 20.44 ? 211 ARG C CB 1 ATOM 4932 C CG . ARG C 1 211 ? -1.103 0.705 64.819 1.00 17.56 ? 211 ARG C CG 1 ATOM 4933 C CD . ARG C 1 211 ? -2.159 1.803 64.980 1.00 22.48 ? 211 ARG C CD 1 ATOM 4934 N NE . ARG C 1 211 ? -2.987 1.637 66.174 1.00 22.84 ? 211 ARG C NE 1 ATOM 4935 C CZ . ARG C 1 211 ? -2.579 1.877 67.419 1.00 26.20 ? 211 ARG C CZ 1 ATOM 4936 N NH1 . ARG C 1 211 ? -1.343 2.295 67.653 1.00 24.93 ? 211 ARG C NH1 1 ATOM 4937 N NH2 . ARG C 1 211 ? -3.414 1.697 68.432 1.00 24.85 ? 211 ARG C NH2 1 ATOM 4938 N N . GLY C 1 212 ? 1.523 -1.211 65.937 1.00 45.68 ? 212 GLY C N 1 ATOM 4939 C CA . GLY C 1 212 ? 2.466 -0.910 67.002 1.00 46.05 ? 212 GLY C CA 1 ATOM 4940 C C . GLY C 1 212 ? 3.273 -2.120 67.430 1.00 49.47 ? 212 GLY C C 1 ATOM 4941 O O . GLY C 1 212 ? 4.498 -2.054 67.520 1.00 60.21 ? 212 GLY C O 1 ATOM 4942 N N . ALA C 1 213 ? 2.586 -3.228 67.696 1.00 58.54 ? 213 ALA C N 1 ATOM 4943 C CA . ALA C 1 213 ? 3.247 -4.463 68.102 1.00 57.11 ? 213 ALA C CA 1 ATOM 4944 C C . ALA C 1 213 ? 4.259 -4.888 67.048 1.00 53.56 ? 213 ALA C C 1 ATOM 4945 O O . ALA C 1 213 ? 3.887 -5.308 65.955 1.00 55.55 ? 213 ALA C O 1 ATOM 4946 C CB . ALA C 1 213 ? 2.220 -5.572 68.353 1.00 46.41 ? 213 ALA C CB 1 ATOM 4947 O OXT . ALA C 1 213 ? 5.470 -4.801 67.269 1.00 67.48 ? 213 ALA C OXT 1 ATOM 4948 N N . GLN D 2 1 ? 18.776 -4.364 13.018 1.00 43.14 ? 1 GLN D N 1 ATOM 4949 C CA . GLN D 2 1 ? 17.678 -4.260 13.975 1.00 45.87 ? 1 GLN D CA 1 ATOM 4950 C C . GLN D 2 1 ? 16.677 -3.156 13.600 1.00 40.57 ? 1 GLN D C 1 ATOM 4951 O O . GLN D 2 1 ? 16.931 -1.980 13.857 1.00 36.47 ? 1 GLN D O 1 ATOM 4952 C CB . GLN D 2 1 ? 18.234 -4.006 15.384 1.00 28.05 ? 1 GLN D CB 1 ATOM 4953 N N . VAL D 2 2 ? 15.546 -3.533 12.998 1.00 37.29 ? 2 VAL D N 1 ATOM 4954 C CA . VAL D 2 2 ? 14.463 -2.577 12.711 1.00 37.28 ? 2 VAL D CA 1 ATOM 4955 C C . VAL D 2 2 ? 13.683 -2.170 13.968 1.00 35.93 ? 2 VAL D C 1 ATOM 4956 O O . VAL D 2 2 ? 13.067 -3.017 14.607 1.00 39.27 ? 2 VAL D O 1 ATOM 4957 C CB . VAL D 2 2 ? 13.424 -3.154 11.722 1.00 31.27 ? 2 VAL D CB 1 ATOM 4958 C CG1 . VAL D 2 2 ? 12.247 -2.188 11.575 1.00 27.27 ? 2 VAL D CG1 1 ATOM 4959 C CG2 . VAL D 2 2 ? 14.050 -3.445 10.377 1.00 32.72 ? 2 VAL D CG2 1 ATOM 4960 N N . GLN D 2 3 ? 13.684 -0.884 14.314 1.00 31.26 ? 3 GLN D N 1 ATOM 4961 C CA . GLN D 2 3 ? 12.971 -0.429 15.508 1.00 33.52 ? 3 GLN D CA 1 ATOM 4962 C C . GLN D 2 3 ? 12.271 0.918 15.336 1.00 34.91 ? 3 GLN D C 1 ATOM 4963 O O . GLN D 2 3 ? 12.778 1.810 14.647 1.00 34.54 ? 3 GLN D O 1 ATOM 4964 C CB . GLN D 2 3 ? 13.909 -0.385 16.725 1.00 31.68 ? 3 GLN D CB 1 ATOM 4965 C CG . GLN D 2 3 ? 14.338 -1.765 17.224 1.00 46.39 ? 3 GLN D CG 1 ATOM 4966 C CD . GLN D 2 3 ? 15.174 -1.728 18.503 1.00 54.81 ? 3 GLN D CD 1 ATOM 4967 O OE1 . GLN D 2 3 ? 15.684 -0.680 18.905 1.00 52.26 ? 3 GLN D OE1 1 ATOM 4968 N NE2 . GLN D 2 3 ? 15.311 -2.884 19.149 1.00 62.05 ? 3 GLN D NE2 1 ATOM 4969 N N . LEU D 2 4 ? 11.102 1.052 15.966 1.00 31.36 ? 4 LEU D N 1 ATOM 4970 C CA . LEU D 2 4 ? 10.403 2.335 16.043 1.00 33.24 ? 4 LEU D CA 1 ATOM 4971 C C . LEU D 2 4 ? 10.242 2.702 17.507 1.00 27.00 ? 4 LEU D C 1 ATOM 4972 O O . LEU D 2 4 ? 9.749 1.902 18.288 1.00 27.82 ? 4 LEU D O 1 ATOM 4973 C CB . LEU D 2 4 ? 9.029 2.289 15.344 1.00 28.03 ? 4 LEU D CB 1 ATOM 4974 C CG . LEU D 2 4 ? 8.988 1.935 13.848 1.00 31.49 ? 4 LEU D CG 1 ATOM 4975 C CD1 . LEU D 2 4 ? 9.001 0.430 13.657 1.00 29.40 ? 4 LEU D CD1 1 ATOM 4976 C CD2 . LEU D 2 4 ? 7.792 2.565 13.106 1.00 24.93 ? 4 LEU D CD2 1 ATOM 4977 N N . LYS D 2 5 ? 10.670 3.905 17.878 1.00 31.41 ? 5 LYS D N 1 ATOM 4978 C CA . LYS D 2 5 ? 10.600 4.355 19.270 1.00 29.53 ? 5 LYS D CA 1 ATOM 4979 C C . LYS D 2 5 ? 9.853 5.677 19.371 1.00 28.42 ? 5 LYS D C 1 ATOM 4980 O O . LYS D 2 5 ? 10.191 6.658 18.695 1.00 28.57 ? 5 LYS D O 1 ATOM 4981 C CB . LYS D 2 5 ? 12.004 4.497 19.851 1.00 28.04 ? 5 LYS D CB 1 ATOM 4982 C CG . LYS D 2 5 ? 12.856 3.260 19.625 1.00 44.60 ? 5 LYS D CG 1 ATOM 4983 C CD . LYS D 2 5 ? 14.253 3.411 20.204 1.00 58.34 ? 5 LYS D CD 1 ATOM 4984 C CE . LYS D 2 5 ? 14.953 2.062 20.248 1.00 58.95 ? 5 LYS D CE 1 ATOM 4985 N NZ . LYS D 2 5 ? 14.099 1.030 20.918 1.00 54.61 ? 5 LYS D NZ 1 ATOM 4986 N N . GLN D 2 6 ? 8.834 5.709 20.219 1.00 24.02 ? 6 GLN D N 1 ATOM 4987 C CA . GLN D 2 6 ? 7.938 6.862 20.250 1.00 23.41 ? 6 GLN D CA 1 ATOM 4988 C C . GLN D 2 6 ? 8.261 7.778 21.424 1.00 24.62 ? 6 GLN D C 1 ATOM 4989 O O . GLN D 2 6 ? 8.956 7.384 22.351 1.00 23.17 ? 6 GLN D O 1 ATOM 4990 C CB . GLN D 2 6 ? 6.483 6.394 20.303 1.00 21.73 ? 6 GLN D CB 1 ATOM 4991 C CG . GLN D 2 6 ? 6.241 5.109 19.522 1.00 27.17 ? 6 GLN D CG 1 ATOM 4992 C CD . GLN D 2 6 ? 4.774 4.780 19.385 1.00 27.37 ? 6 GLN D CD 1 ATOM 4993 O OE1 . GLN D 2 6 ? 4.400 3.713 18.883 1.00 24.77 ? 6 GLN D OE1 1 ATOM 4994 N NE2 . GLN D 2 6 ? 3.927 5.698 19.833 1.00 26.36 ? 6 GLN D NE2 1 ATOM 4995 N N . SER D 2 7 ? 7.778 9.012 21.379 1.00 24.67 ? 7 SER D N 1 ATOM 4996 C CA . SER D 2 7 ? 7.973 9.910 22.508 1.00 25.80 ? 7 SER D CA 1 ATOM 4997 C C . SER D 2 7 ? 7.088 9.476 23.690 1.00 37.47 ? 7 SER D C 1 ATOM 4998 O O . SER D 2 7 ? 6.136 8.702 23.518 1.00 28.78 ? 7 SER D O 1 ATOM 4999 C CB . SER D 2 7 ? 7.704 11.354 22.103 1.00 22.53 ? 7 SER D CB 1 ATOM 5000 O OG . SER D 2 7 ? 6.601 11.410 21.233 1.00 29.01 ? 7 SER D OG 1 ATOM 5001 N N . GLY D 2 8 ? 7.412 9.974 24.882 1.00 30.16 ? 8 GLY D N 1 ATOM 5002 C CA . GLY D 2 8 ? 6.776 9.526 26.112 1.00 28.87 ? 8 GLY D CA 1 ATOM 5003 C C . GLY D 2 8 ? 5.283 9.788 26.256 1.00 30.70 ? 8 GLY D C 1 ATOM 5004 O O . GLY D 2 8 ? 4.709 10.610 25.535 1.00 25.30 ? 8 GLY D O 1 ATOM 5005 N N . PRO D 2 9 ? 4.646 9.095 27.216 1.00 27.61 ? 9 PRO D N 1 ATOM 5006 C CA . PRO D 2 9 ? 3.220 9.255 27.490 1.00 25.26 ? 9 PRO D CA 1 ATOM 5007 C C . PRO D 2 9 ? 2.951 10.593 28.174 1.00 32.83 ? 9 PRO D C 1 ATOM 5008 O O . PRO D 2 9 ? 3.865 11.246 28.689 1.00 24.15 ? 9 PRO D O 1 ATOM 5009 C CB . PRO D 2 9 ? 2.945 8.126 28.473 1.00 21.97 ? 9 PRO D CB 1 ATOM 5010 C CG . PRO D 2 9 ? 4.198 8.033 29.245 1.00 18.64 ? 9 PRO D CG 1 ATOM 5011 C CD . PRO D 2 9 ? 5.289 8.233 28.221 1.00 25.16 ? 9 PRO D CD 1 ATOM 5012 N N . GLY D 2 10 ? 1.690 11.002 28.188 1.00 28.36 ? 10 GLY D N 1 ATOM 5013 C CA . GLY D 2 10 ? 1.354 12.235 28.848 1.00 23.38 ? 10 GLY D CA 1 ATOM 5014 C C . GLY D 2 10 ? -0.076 12.672 28.706 1.00 24.36 ? 10 GLY D C 1 ATOM 5015 O O . GLY D 2 10 ? -0.863 12.101 27.950 1.00 29.61 ? 10 GLY D O 1 ATOM 5016 N N . LEU D 2 11 ? -0.382 13.720 29.450 1.00 25.61 ? 11 LEU D N 1 ATOM 5017 C CA . LEU D 2 11 ? -1.701 14.307 29.534 1.00 27.94 ? 11 LEU D CA 1 ATOM 5018 C C . LEU D 2 11 ? -1.868 15.368 28.439 1.00 28.95 ? 11 LEU D C 1 ATOM 5019 O O . LEU D 2 11 ? -0.918 16.073 28.110 1.00 32.75 ? 11 LEU D O 1 ATOM 5020 C CB . LEU D 2 11 ? -1.837 14.937 30.925 1.00 15.86 ? 11 LEU D CB 1 ATOM 5021 C CG . LEU D 2 11 ? -3.188 15.482 31.358 1.00 25.56 ? 11 LEU D CG 1 ATOM 5022 C CD1 . LEU D 2 11 ? -4.229 14.386 31.358 1.00 27.69 ? 11 LEU D CD1 1 ATOM 5023 C CD2 . LEU D 2 11 ? -3.030 16.066 32.729 1.00 30.16 ? 11 LEU D CD2 1 ATOM 5024 N N . VAL D 2 12 ? -3.060 15.462 27.860 1.00 26.69 ? 12 VAL D N 1 ATOM 5025 C CA . VAL D 2 12 ? -3.391 16.557 26.942 1.00 29.47 ? 12 VAL D CA 1 ATOM 5026 C C . VAL D 2 12 ? -4.757 17.142 27.316 1.00 34.83 ? 12 VAL D C 1 ATOM 5027 O O . VAL D 2 12 ? -5.719 16.407 27.545 1.00 35.43 ? 12 VAL D O 1 ATOM 5028 C CB . VAL D 2 12 ? -3.386 16.091 25.454 1.00 33.17 ? 12 VAL D CB 1 ATOM 5029 C CG1 . VAL D 2 12 ? -4.239 14.857 25.279 1.00 46.44 ? 12 VAL D CG1 1 ATOM 5030 C CG2 . VAL D 2 12 ? -3.868 17.197 24.522 1.00 35.13 ? 12 VAL D CG2 1 ATOM 5031 N N . GLN D 2 13 ? -4.836 18.463 27.412 1.00 35.55 ? 13 GLN D N 1 ATOM 5032 C CA . GLN D 2 13 ? -6.077 19.121 27.810 1.00 37.20 ? 13 GLN D CA 1 ATOM 5033 C C . GLN D 2 13 ? -7.140 18.991 26.724 1.00 37.20 ? 13 GLN D C 1 ATOM 5034 O O . GLN D 2 13 ? -6.817 19.029 25.541 1.00 36.89 ? 13 GLN D O 1 ATOM 5035 C CB . GLN D 2 13 ? -5.810 20.596 28.114 1.00 36.04 ? 13 GLN D CB 1 ATOM 5036 C CG . GLN D 2 13 ? -4.785 20.813 29.214 1.00 40.78 ? 13 GLN D CG 1 ATOM 5037 C CD . GLN D 2 13 ? -5.248 20.246 30.552 1.00 52.71 ? 13 GLN D CD 1 ATOM 5038 O OE1 . GLN D 2 13 ? -6.415 20.393 30.919 1.00 56.43 ? 13 GLN D OE1 1 ATOM 5039 N NE2 . GLN D 2 13 ? -4.338 19.586 31.282 1.00 40.03 ? 13 GLN D NE2 1 ATOM 5040 N N . PRO D 2 14 ? -8.411 18.820 27.126 1.00 35.76 ? 14 PRO D N 1 ATOM 5041 C CA . PRO D 2 14 ? -9.510 18.796 26.159 1.00 35.07 ? 14 PRO D CA 1 ATOM 5042 C C . PRO D 2 14 ? -9.429 19.981 25.202 1.00 43.31 ? 14 PRO D C 1 ATOM 5043 O O . PRO D 2 14 ? -9.118 21.102 25.623 1.00 40.48 ? 14 PRO D O 1 ATOM 5044 C CB . PRO D 2 14 ? -10.748 18.897 27.046 1.00 36.79 ? 14 PRO D CB 1 ATOM 5045 C CG . PRO D 2 14 ? -10.338 18.240 28.322 1.00 32.00 ? 14 PRO D CG 1 ATOM 5046 C CD . PRO D 2 14 ? -8.888 18.607 28.505 1.00 41.06 ? 14 PRO D CD 1 ATOM 5047 N N . SER D 2 15 ? -9.676 19.700 23.925 1.00 37.38 ? 15 SER D N 1 ATOM 5048 C CA . SER D 2 15 ? -9.555 20.664 22.826 1.00 41.47 ? 15 SER D CA 1 ATOM 5049 C C . SER D 2 15 ? -8.121 21.002 22.379 1.00 36.52 ? 15 SER D C 1 ATOM 5050 O O . SER D 2 15 ? -7.947 21.564 21.305 1.00 45.34 ? 15 SER D O 1 ATOM 5051 C CB . SER D 2 15 ? -10.364 21.944 23.093 1.00 38.95 ? 15 SER D CB 1 ATOM 5052 O OG . SER D 2 15 ? -11.729 21.636 23.319 1.00 52.37 ? 15 SER D OG 1 ATOM 5053 N N . GLN D 2 16 ? -7.105 20.672 23.175 1.00 32.71 ? 16 GLN D N 1 ATOM 5054 C CA . GLN D 2 16 ? -5.717 20.882 22.727 1.00 38.88 ? 16 GLN D CA 1 ATOM 5055 C C . GLN D 2 16 ? -5.268 19.787 21.756 1.00 39.97 ? 16 GLN D C 1 ATOM 5056 O O . GLN D 2 16 ? -6.012 18.839 21.487 1.00 42.80 ? 16 GLN D O 1 ATOM 5057 C CB . GLN D 2 16 ? -4.726 20.960 23.895 1.00 42.23 ? 16 GLN D CB 1 ATOM 5058 C CG . GLN D 2 16 ? -5.065 21.967 24.970 1.00 44.39 ? 16 GLN D CG 1 ATOM 5059 C CD . GLN D 2 16 ? -5.391 23.332 24.417 1.00 54.84 ? 16 GLN D CD 1 ATOM 5060 O OE1 . GLN D 2 16 ? -4.495 24.134 24.157 1.00 60.84 ? 16 GLN D OE1 1 ATOM 5061 N NE2 . GLN D 2 16 ? -6.682 23.612 24.243 1.00 53.86 ? 16 GLN D NE2 1 ATOM 5062 N N . SER D 2 17 ? -4.046 19.914 21.245 1.00 38.84 ? 17 SER D N 1 ATOM 5063 C CA . SER D 2 17 ? -3.546 18.994 20.226 1.00 37.30 ? 17 SER D CA 1 ATOM 5064 C C . SER D 2 17 ? -2.638 17.931 20.826 1.00 36.01 ? 17 SER D C 1 ATOM 5065 O O . SER D 2 17 ? -2.127 18.094 21.925 1.00 35.18 ? 17 SER D O 1 ATOM 5066 C CB . SER D 2 17 ? -2.762 19.756 19.168 1.00 33.06 ? 17 SER D CB 1 ATOM 5067 O OG . SER D 2 17 ? -1.575 20.265 19.745 1.00 36.61 ? 17 SER D OG 1 ATOM 5068 N N . LEU D 2 18 ? -2.422 16.855 20.081 1.00 31.59 ? 18 LEU D N 1 ATOM 5069 C CA . LEU D 2 18 ? -1.587 15.764 20.542 1.00 24.52 ? 18 LEU D CA 1 ATOM 5070 C C . LEU D 2 18 ? -0.422 15.607 19.582 1.00 31.10 ? 18 LEU D C 1 ATOM 5071 O O . LEU D 2 18 ? -0.620 15.535 18.376 1.00 34.93 ? 18 LEU D O 1 ATOM 5072 C CB . LEU D 2 18 ? -2.407 14.483 20.596 1.00 21.95 ? 18 LEU D CB 1 ATOM 5073 C CG . LEU D 2 18 ? -1.719 13.132 20.478 1.00 25.51 ? 18 LEU D CG 1 ATOM 5074 C CD1 . LEU D 2 18 ? -0.675 12.937 21.557 1.00 26.47 ? 18 LEU D CD1 1 ATOM 5075 C CD2 . LEU D 2 18 ? -2.785 12.039 20.549 1.00 27.70 ? 18 LEU D CD2 1 ATOM 5076 N N . SER D 2 19 ? 0.794 15.556 20.115 1.00 27.59 ? 19 SER D N 1 ATOM 5077 C CA . SER D 2 19 ? 1.976 15.432 19.278 1.00 25.95 ? 19 SER D CA 1 ATOM 5078 C C . SER D 2 19 ? 2.858 14.277 19.694 1.00 21.50 ? 19 SER D C 1 ATOM 5079 O O . SER D 2 19 ? 3.425 14.279 20.777 1.00 22.78 ? 19 SER D O 1 ATOM 5080 C CB . SER D 2 19 ? 2.785 16.725 19.293 1.00 29.15 ? 19 SER D CB 1 ATOM 5081 O OG . SER D 2 19 ? 2.165 17.702 18.483 1.00 38.24 ? 19 SER D OG 1 ATOM 5082 N N . ILE D 2 20 ? 2.977 13.289 18.816 1.00 26.15 ? 20 ILE D N 1 ATOM 5083 C CA . ILE D 2 20 ? 3.866 12.165 19.064 1.00 24.66 ? 20 ILE D CA 1 ATOM 5084 C C . ILE D 2 20 ? 4.957 12.104 18.009 1.00 24.46 ? 20 ILE D C 1 ATOM 5085 O O . ILE D 2 20 ? 4.696 12.326 16.830 1.00 25.27 ? 20 ILE D O 1 ATOM 5086 C CB . ILE D 2 20 ? 3.100 10.850 19.091 1.00 19.08 ? 20 ILE D CB 1 ATOM 5087 C CG1 . ILE D 2 20 ? 1.963 10.943 20.110 1.00 18.29 ? 20 ILE D CG1 1 ATOM 5088 C CG2 . ILE D 2 20 ? 4.041 9.696 19.422 1.00 17.29 ? 20 ILE D CG2 1 ATOM 5089 C CD1 . ILE D 2 20 ? 0.950 9.838 19.984 1.00 20.76 ? 20 ILE D CD1 1 ATOM 5090 N N . THR D 2 21 ? 6.184 11.833 18.444 1.00 24.04 ? 21 THR D N 1 ATOM 5091 C CA . THR D 2 21 ? 7.291 11.608 17.528 1.00 20.66 ? 21 THR D CA 1 ATOM 5092 C C . THR D 2 21 ? 7.668 10.136 17.439 1.00 24.47 ? 21 THR D C 1 ATOM 5093 O O . THR D 2 21 ? 7.937 9.499 18.460 1.00 22.07 ? 21 THR D O 1 ATOM 5094 C CB . THR D 2 21 ? 8.526 12.394 17.964 1.00 21.55 ? 21 THR D CB 1 ATOM 5095 O OG1 . THR D 2 21 ? 8.251 13.793 17.840 1.00 27.41 ? 21 THR D OG1 1 ATOM 5096 C CG2 . THR D 2 21 ? 9.734 12.029 17.089 1.00 26.19 ? 21 THR D CG2 1 ATOM 5097 N N . CYS D 2 22 ? 7.696 9.607 16.214 1.00 26.80 ? 22 CYS D N 1 ATOM 5098 C CA . CYS D 2 22 ? 8.216 8.265 15.955 1.00 21.30 ? 22 CYS D CA 1 ATOM 5099 C C . CYS D 2 22 ? 9.601 8.347 15.336 1.00 26.99 ? 22 CYS D C 1 ATOM 5100 O O . CYS D 2 22 ? 9.795 9.001 14.315 1.00 31.03 ? 22 CYS D O 1 ATOM 5101 C CB . CYS D 2 22 ? 7.286 7.484 15.030 1.00 17.42 ? 22 CYS D CB 1 ATOM 5102 S SG . CYS D 2 22 ? 7.764 5.746 14.736 1.00 24.68 ? 22 CYS D SG 1 ATOM 5103 N N . THR D 2 23 ? 10.556 7.663 15.954 1.00 24.40 ? 23 THR D N 1 ATOM 5104 C CA . THR D 2 23 ? 11.952 7.707 15.540 1.00 21.68 ? 23 THR D CA 1 ATOM 5105 C C . THR D 2 23 ? 12.405 6.312 15.112 1.00 31.92 ? 23 THR D C 1 ATOM 5106 O O . THR D 2 23 ? 12.514 5.406 15.939 1.00 35.45 ? 23 THR D O 1 ATOM 5107 C CB . THR D 2 23 ? 12.854 8.168 16.706 1.00 26.19 ? 23 THR D CB 1 ATOM 5108 O OG1 . THR D 2 23 ? 12.439 9.465 17.163 1.00 34.23 ? 23 THR D OG1 1 ATOM 5109 C CG2 . THR D 2 23 ? 14.317 8.198 16.280 1.00 15.12 ? 23 THR D CG2 1 ATOM 5110 N N . VAL D 2 24 ? 12.678 6.130 13.828 1.00 30.13 ? 24 VAL D N 1 ATOM 5111 C CA . VAL D 2 24 ? 13.003 4.797 13.335 1.00 33.66 ? 24 VAL D CA 1 ATOM 5112 C C . VAL D 2 24 ? 14.498 4.570 13.151 1.00 28.47 ? 24 VAL D C 1 ATOM 5113 O O . VAL D 2 24 ? 15.278 5.515 13.031 1.00 26.97 ? 24 VAL D O 1 ATOM 5114 C CB . VAL D 2 24 ? 12.300 4.497 11.990 1.00 34.04 ? 24 VAL D CB 1 ATOM 5115 C CG1 . VAL D 2 24 ? 10.825 4.885 12.064 1.00 26.56 ? 24 VAL D CG1 1 ATOM 5116 C CG2 . VAL D 2 24 ? 13.010 5.201 10.836 1.00 20.76 ? 24 VAL D CG2 1 ATOM 5117 N N . SER D 2 25 ? 14.878 3.300 13.114 1.00 25.94 ? 25 SER D N 1 ATOM 5118 C CA . SER D 2 25 ? 16.250 2.888 12.843 1.00 24.19 ? 25 SER D CA 1 ATOM 5119 C C . SER D 2 25 ? 16.233 1.477 12.258 1.00 31.78 ? 25 SER D C 1 ATOM 5120 O O . SER D 2 25 ? 15.363 0.671 12.599 1.00 37.37 ? 25 SER D O 1 ATOM 5121 C CB . SER D 2 25 ? 17.069 2.911 14.131 1.00 26.29 ? 25 SER D CB 1 ATOM 5122 O OG . SER D 2 25 ? 16.501 2.037 15.087 1.00 33.83 ? 25 SER D OG 1 ATOM 5123 N N . GLY D 2 26 ? 17.184 1.171 11.381 1.00 30.63 ? 26 GLY D N 1 ATOM 5124 C CA . GLY D 2 26 ? 17.238 -0.142 10.762 1.00 21.76 ? 26 GLY D CA 1 ATOM 5125 C C . GLY D 2 26 ? 16.605 -0.156 9.383 1.00 25.40 ? 26 GLY D C 1 ATOM 5126 O O . GLY D 2 26 ? 16.500 -1.213 8.753 1.00 23.62 ? 26 GLY D O 1 ATOM 5127 N N . PHE D 2 27 ? 16.178 1.021 8.927 1.00 21.14 ? 27 PHE D N 1 ATOM 5128 C CA . PHE D 2 27 ? 15.583 1.207 7.600 1.00 21.76 ? 27 PHE D CA 1 ATOM 5129 C C . PHE D 2 27 ? 15.380 2.697 7.397 1.00 25.51 ? 27 PHE D C 1 ATOM 5130 O O . PHE D 2 27 ? 15.347 3.463 8.358 1.00 30.42 ? 27 PHE D O 1 ATOM 5131 C CB . PHE D 2 27 ? 14.226 0.492 7.461 1.00 21.35 ? 27 PHE D CB 1 ATOM 5132 C CG . PHE D 2 27 ? 13.079 1.207 8.153 1.00 20.96 ? 27 PHE D CG 1 ATOM 5133 C CD1 . PHE D 2 27 ? 12.800 0.972 9.492 1.00 21.75 ? 27 PHE D CD1 1 ATOM 5134 C CD2 . PHE D 2 27 ? 12.281 2.108 7.459 1.00 26.87 ? 27 PHE D CD2 1 ATOM 5135 C CE1 . PHE D 2 27 ? 11.754 1.617 10.129 1.00 20.82 ? 27 PHE D CE1 1 ATOM 5136 C CE2 . PHE D 2 27 ? 11.227 2.763 8.092 1.00 28.77 ? 27 PHE D CE2 1 ATOM 5137 C CZ . PHE D 2 27 ? 10.964 2.509 9.434 1.00 27.09 ? 27 PHE D CZ 1 ATOM 5138 N N . SER D 2 28 ? 15.213 3.109 6.150 1.00 27.60 ? 28 SER D N 1 ATOM 5139 C CA . SER D 2 28 ? 15.065 4.523 5.841 1.00 30.12 ? 28 SER D CA 1 ATOM 5140 C C . SER D 2 28 ? 13.606 4.927 5.585 1.00 34.79 ? 28 SER D C 1 ATOM 5141 O O . SER D 2 28 ? 12.808 4.154 5.048 1.00 29.19 ? 28 SER D O 1 ATOM 5142 C CB . SER D 2 28 ? 15.951 4.890 4.650 1.00 29.12 ? 28 SER D CB 1 ATOM 5143 O OG . SER D 2 28 ? 15.643 6.184 4.162 1.00 38.73 ? 28 SER D OG 1 ATOM 5144 N N . LEU D 2 29 ? 13.264 6.149 5.973 1.00 32.43 ? 29 LEU D N 1 ATOM 5145 C CA . LEU D 2 29 ? 11.918 6.645 5.763 1.00 26.73 ? 29 LEU D CA 1 ATOM 5146 C C . LEU D 2 29 ? 11.684 6.859 4.281 1.00 33.87 ? 29 LEU D C 1 ATOM 5147 O O . LEU D 2 29 ? 10.541 6.926 3.830 1.00 38.33 ? 29 LEU D O 1 ATOM 5148 C CB . LEU D 2 29 ? 11.681 7.931 6.554 1.00 27.88 ? 29 LEU D CB 1 ATOM 5149 C CG . LEU D 2 29 ? 11.693 7.719 8.069 1.00 25.03 ? 29 LEU D CG 1 ATOM 5150 C CD1 . LEU D 2 29 ? 11.522 9.035 8.797 1.00 25.09 ? 29 LEU D CD1 1 ATOM 5151 C CD2 . LEU D 2 29 ? 10.607 6.730 8.467 1.00 18.61 ? 29 LEU D CD2 1 ATOM 5152 N N . THR D 2 30 ? 12.772 6.945 3.518 1.00 33.97 ? 30 THR D N 1 ATOM 5153 C CA . THR D 2 30 ? 12.674 7.072 2.064 1.00 37.28 ? 30 THR D CA 1 ATOM 5154 C C . THR D 2 30 ? 12.324 5.746 1.392 1.00 31.67 ? 30 THR D C 1 ATOM 5155 O O . THR D 2 30 ? 11.996 5.732 0.215 1.00 29.83 ? 30 THR D O 1 ATOM 5156 C CB . THR D 2 30 ? 13.973 7.619 1.427 1.00 26.86 ? 30 THR D CB 1 ATOM 5157 O OG1 . THR D 2 30 ? 15.026 6.666 1.607 1.00 35.59 ? 30 THR D OG1 1 ATOM 5158 C CG2 . THR D 2 30 ? 14.374 8.935 2.054 1.00 29.98 ? 30 THR D CG2 1 ATOM 5159 N N . ASN D 2 31 ? 12.407 4.640 2.133 1.00 28.67 ? 31 ASN D N 1 ATOM 5160 C CA . ASN D 2 31 ? 12.081 3.317 1.590 1.00 26.20 ? 31 ASN D CA 1 ATOM 5161 C C . ASN D 2 31 ? 10.775 2.688 2.096 1.00 32.13 ? 31 ASN D C 1 ATOM 5162 O O . ASN D 2 31 ? 10.238 1.798 1.456 1.00 31.90 ? 31 ASN D O 1 ATOM 5163 C CB . ASN D 2 31 ? 13.224 2.335 1.832 1.00 28.89 ? 31 ASN D CB 1 ATOM 5164 C CG . ASN D 2 31 ? 14.451 2.661 1.024 1.00 30.44 ? 31 ASN D CG 1 ATOM 5165 O OD1 . ASN D 2 31 ? 14.355 3.256 -0.039 1.00 33.10 ? 31 ASN D OD1 1 ATOM 5166 N ND2 . ASN D 2 31 ? 15.620 2.274 1.527 1.00 29.71 ? 31 ASN D ND2 1 ATOM 5167 N N . TYR D 2 32 ? 10.277 3.124 3.250 1.00 35.29 ? 32 TYR D N 1 ATOM 5168 C CA . TYR D 2 32 ? 9.050 2.544 3.816 1.00 28.90 ? 32 TYR D CA 1 ATOM 5169 C C . TYR D 2 32 ? 8.077 3.600 4.331 1.00 23.12 ? 32 TYR D C 1 ATOM 5170 O O . TYR D 2 32 ? 8.488 4.631 4.850 1.00 28.53 ? 32 TYR D O 1 ATOM 5171 C CB . TYR D 2 32 ? 9.390 1.589 4.950 1.00 25.35 ? 32 TYR D CB 1 ATOM 5172 C CG . TYR D 2 32 ? 10.108 0.324 4.537 1.00 27.91 ? 32 TYR D CG 1 ATOM 5173 C CD1 . TYR D 2 32 ? 9.406 -0.865 4.345 1.00 21.32 ? 32 TYR D CD1 1 ATOM 5174 C CD2 . TYR D 2 32 ? 11.489 0.311 4.358 1.00 23.55 ? 32 TYR D CD2 1 ATOM 5175 C CE1 . TYR D 2 32 ? 10.058 -2.025 3.982 1.00 24.65 ? 32 TYR D CE1 1 ATOM 5176 C CE2 . TYR D 2 32 ? 12.150 -0.846 3.990 1.00 23.77 ? 32 TYR D CE2 1 ATOM 5177 C CZ . TYR D 2 32 ? 11.428 -2.014 3.809 1.00 23.22 ? 32 TYR D CZ 1 ATOM 5178 O OH . TYR D 2 32 ? 12.069 -3.171 3.449 1.00 27.47 ? 32 TYR D OH 1 ATOM 5179 N N . GLY D 2 33 ? 6.786 3.355 4.158 1.00 21.81 ? 33 GLY D N 1 ATOM 5180 C CA . GLY D 2 33 ? 5.787 4.202 4.776 1.00 24.17 ? 33 GLY D CA 1 ATOM 5181 C C . GLY D 2 33 ? 5.738 3.935 6.274 1.00 24.09 ? 33 GLY D C 1 ATOM 5182 O O . GLY D 2 33 ? 6.095 2.846 6.733 1.00 24.50 ? 33 GLY D O 1 ATOM 5183 N N . VAL D 2 34 ? 5.303 4.925 7.042 1.00 23.12 ? 34 VAL D N 1 ATOM 5184 C CA . VAL D 2 34 ? 5.075 4.724 8.475 1.00 19.28 ? 34 VAL D CA 1 ATOM 5185 C C . VAL D 2 34 ? 3.615 4.998 8.798 1.00 18.82 ? 34 VAL D C 1 ATOM 5186 O O . VAL D 2 34 ? 3.083 6.054 8.472 1.00 23.10 ? 34 VAL D O 1 ATOM 5187 C CB . VAL D 2 34 ? 6.021 5.588 9.339 1.00 23.33 ? 34 VAL D CB 1 ATOM 5188 C CG1 . VAL D 2 34 ? 5.509 5.704 10.784 1.00 20.74 ? 34 VAL D CG1 1 ATOM 5189 C CG2 . VAL D 2 34 ? 7.435 5.016 9.301 1.00 18.40 ? 34 VAL D CG2 1 ATOM 5190 N N . HIS D 2 35 ? 2.962 4.029 9.424 1.00 28.35 ? 35 HIS D N 1 ATOM 5191 C CA . HIS D 2 35 ? 1.539 4.137 9.712 1.00 24.96 ? 35 HIS D CA 1 ATOM 5192 C C . HIS D 2 35 ? 1.315 4.508 11.159 1.00 26.68 ? 35 HIS D C 1 ATOM 5193 O O . HIS D 2 35 ? 2.224 4.385 11.982 1.00 23.13 ? 35 HIS D O 1 ATOM 5194 C CB . HIS D 2 35 ? 0.855 2.806 9.441 1.00 23.93 ? 35 HIS D CB 1 ATOM 5195 C CG . HIS D 2 35 ? 0.960 2.349 8.022 1.00 24.80 ? 35 HIS D CG 1 ATOM 5196 N ND1 . HIS D 2 35 ? -0.143 2.129 7.227 1.00 26.73 ? 35 HIS D ND1 1 ATOM 5197 C CD2 . HIS D 2 35 ? 2.040 2.064 7.256 1.00 18.94 ? 35 HIS D CD2 1 ATOM 5198 C CE1 . HIS D 2 35 ? 0.251 1.724 6.032 1.00 31.95 ? 35 HIS D CE1 1 ATOM 5199 N NE2 . HIS D 2 35 ? 1.572 1.673 6.026 1.00 27.51 ? 35 HIS D NE2 1 ATOM 5200 N N . TRP D 2 36 ? 0.098 4.955 11.467 1.00 24.38 ? 36 TRP D N 1 ATOM 5201 C CA . TRP D 2 36 ? -0.289 5.206 12.848 1.00 19.43 ? 36 TRP D CA 1 ATOM 5202 C C . TRP D 2 36 ? -1.596 4.502 13.182 1.00 27.60 ? 36 TRP D C 1 ATOM 5203 O O . TRP D 2 36 ? -2.595 4.628 12.474 1.00 27.11 ? 36 TRP D O 1 ATOM 5204 C CB . TRP D 2 36 ? -0.371 6.706 13.149 1.00 22.33 ? 36 TRP D CB 1 ATOM 5205 C CG . TRP D 2 36 ? 0.974 7.364 13.025 1.00 28.12 ? 36 TRP D CG 1 ATOM 5206 C CD1 . TRP D 2 36 ? 1.607 7.711 11.866 1.00 24.03 ? 36 TRP D CD1 1 ATOM 5207 C CD2 . TRP D 2 36 ? 1.870 7.721 14.091 1.00 25.42 ? 36 TRP D CD2 1 ATOM 5208 N NE1 . TRP D 2 36 ? 2.830 8.269 12.140 1.00 23.97 ? 36 TRP D NE1 1 ATOM 5209 C CE2 . TRP D 2 36 ? 3.017 8.288 13.499 1.00 21.15 ? 36 TRP D CE2 1 ATOM 5210 C CE3 . TRP D 2 36 ? 1.810 7.624 15.485 1.00 23.24 ? 36 TRP D CE3 1 ATOM 5211 C CZ2 . TRP D 2 36 ? 4.092 8.752 14.249 1.00 19.85 ? 36 TRP D CZ2 1 ATOM 5212 C CZ3 . TRP D 2 36 ? 2.883 8.084 16.230 1.00 23.72 ? 36 TRP D CZ3 1 ATOM 5213 C CH2 . TRP D 2 36 ? 4.004 8.646 15.612 1.00 24.17 ? 36 TRP D CH2 1 ATOM 5214 N N . VAL D 2 37 ? -1.561 3.743 14.269 1.00 28.34 ? 37 VAL D N 1 ATOM 5215 C CA . VAL D 2 37 ? -2.700 3.002 14.756 1.00 27.30 ? 37 VAL D CA 1 ATOM 5216 C C . VAL D 2 37 ? -2.901 3.371 16.225 1.00 25.09 ? 37 VAL D C 1 ATOM 5217 O O . VAL D 2 37 ? -1.935 3.595 16.952 1.00 28.92 ? 37 VAL D O 1 ATOM 5218 C CB . VAL D 2 37 ? -2.442 1.486 14.606 1.00 22.83 ? 37 VAL D CB 1 ATOM 5219 C CG1 . VAL D 2 37 ? -3.530 0.651 15.306 1.00 18.51 ? 37 VAL D CG1 1 ATOM 5220 C CG2 . VAL D 2 37 ? -2.326 1.125 13.128 1.00 18.67 ? 37 VAL D CG2 1 ATOM 5221 N N . ARG D 2 38 ? -4.151 3.454 16.663 1.00 18.58 ? 38 ARG D N 1 ATOM 5222 C CA . ARG D 2 38 ? -4.423 3.659 18.072 1.00 21.49 ? 38 ARG D CA 1 ATOM 5223 C C . ARG D 2 38 ? -5.306 2.554 18.628 1.00 24.71 ? 38 ARG D C 1 ATOM 5224 O O . ARG D 2 38 ? -6.045 1.904 17.889 1.00 34.69 ? 38 ARG D O 1 ATOM 5225 C CB . ARG D 2 38 ? -5.033 5.037 18.322 1.00 22.53 ? 38 ARG D CB 1 ATOM 5226 C CG . ARG D 2 38 ? -6.492 5.163 17.939 1.00 22.42 ? 38 ARG D CG 1 ATOM 5227 C CD . ARG D 2 38 ? -6.993 6.560 18.235 1.00 18.14 ? 38 ARG D CD 1 ATOM 5228 N NE . ARG D 2 38 ? -8.413 6.698 17.962 1.00 26.11 ? 38 ARG D NE 1 ATOM 5229 C CZ . ARG D 2 38 ? -9.097 7.818 18.139 1.00 22.79 ? 38 ARG D CZ 1 ATOM 5230 N NH1 . ARG D 2 38 ? -8.488 8.903 18.582 1.00 19.17 ? 38 ARG D NH1 1 ATOM 5231 N NH2 . ARG D 2 38 ? -10.388 7.845 17.862 1.00 30.09 ? 38 ARG D NH2 1 ATOM 5232 N N . GLN D 2 39 ? -5.212 2.333 19.934 1.00 24.11 ? 39 GLN D N 1 ATOM 5233 C CA . GLN D 2 39 ? -6.040 1.338 20.606 1.00 23.45 ? 39 GLN D CA 1 ATOM 5234 C C . GLN D 2 39 ? -6.820 2.028 21.719 1.00 26.14 ? 39 GLN D C 1 ATOM 5235 O O . GLN D 2 39 ? -6.254 2.370 22.749 1.00 28.61 ? 39 GLN D O 1 ATOM 5236 C CB . GLN D 2 39 ? -5.148 0.238 21.180 1.00 23.83 ? 39 GLN D CB 1 ATOM 5237 C CG . GLN D 2 39 ? -5.864 -1.023 21.627 1.00 23.76 ? 39 GLN D CG 1 ATOM 5238 C CD . GLN D 2 39 ? -4.913 -2.205 21.759 1.00 26.81 ? 39 GLN D CD 1 ATOM 5239 O OE1 . GLN D 2 39 ? -3.723 -2.042 22.075 1.00 27.36 ? 39 GLN D OE1 1 ATOM 5240 N NE2 . GLN D 2 39 ? -5.428 -3.404 21.495 1.00 27.96 ? 39 GLN D NE2 1 ATOM 5241 N N . SER D 2 40 ? -8.109 2.262 21.504 1.00 32.43 ? 40 SER D N 1 ATOM 5242 C CA . SER D 2 40 ? -8.916 2.985 22.489 1.00 32.01 ? 40 SER D CA 1 ATOM 5243 C C . SER D 2 40 ? -9.797 2.028 23.279 1.00 38.69 ? 40 SER D C 1 ATOM 5244 O O . SER D 2 40 ? -10.156 0.964 22.778 1.00 38.40 ? 40 SER D O 1 ATOM 5245 C CB . SER D 2 40 ? -9.764 4.069 21.818 1.00 31.27 ? 40 SER D CB 1 ATOM 5246 O OG . SER D 2 40 ? -10.847 3.517 21.091 1.00 35.36 ? 40 SER D OG 1 ATOM 5247 N N . PRO D 2 41 ? -10.134 2.398 24.525 1.00 44.22 ? 41 PRO D N 1 ATOM 5248 C CA . PRO D 2 41 ? -10.960 1.531 25.368 1.00 39.38 ? 41 PRO D CA 1 ATOM 5249 C C . PRO D 2 41 ? -12.273 1.129 24.710 1.00 41.08 ? 41 PRO D C 1 ATOM 5250 O O . PRO D 2 41 ? -12.696 -0.017 24.844 1.00 50.67 ? 41 PRO D O 1 ATOM 5251 C CB . PRO D 2 41 ? -11.205 2.382 26.628 1.00 38.59 ? 41 PRO D CB 1 ATOM 5252 C CG . PRO D 2 41 ? -10.735 3.759 26.293 1.00 35.03 ? 41 PRO D CG 1 ATOM 5253 C CD . PRO D 2 41 ? -9.672 3.586 25.263 1.00 43.92 ? 41 PRO D CD 1 ATOM 5254 N N . GLY D 2 42 ? -12.892 2.050 23.982 1.00 38.05 ? 42 GLY D N 1 ATOM 5255 C CA . GLY D 2 42 ? -14.168 1.779 23.347 1.00 41.47 ? 42 GLY D CA 1 ATOM 5256 C C . GLY D 2 42 ? -14.080 1.054 22.012 1.00 56.08 ? 42 GLY D C 1 ATOM 5257 O O . GLY D 2 42 ? -14.710 0.012 21.821 1.00 56.76 ? 42 GLY D O 1 ATOM 5258 N N . LYS D 2 43 ? -13.289 1.595 21.088 1.00 42.32 ? 43 LYS D N 1 ATOM 5259 C CA . LYS D 2 43 ? -13.266 1.097 19.714 1.00 45.40 ? 43 LYS D CA 1 ATOM 5260 C C . LYS D 2 43 ? -12.092 0.208 19.348 1.00 36.16 ? 43 LYS D C 1 ATOM 5261 O O . LYS D 2 43 ? -11.899 -0.080 18.177 1.00 38.59 ? 43 LYS D O 1 ATOM 5262 C CB . LYS D 2 43 ? -13.277 2.268 18.743 1.00 46.12 ? 43 LYS D CB 1 ATOM 5263 C CG . LYS D 2 43 ? -14.388 3.265 18.984 1.00 48.47 ? 43 LYS D CG 1 ATOM 5264 C CD . LYS D 2 43 ? -14.381 4.354 17.920 1.00 52.93 ? 43 LYS D CD 1 ATOM 5265 C CE . LYS D 2 43 ? -15.470 4.140 16.873 1.00 63.56 ? 43 LYS D CE 1 ATOM 5266 N NZ . LYS D 2 43 ? -15.428 5.186 15.803 1.00 50.73 ? 43 LYS D NZ 1 ATOM 5267 N N . GLY D 2 44 ? -11.292 -0.193 20.327 1.00 38.92 ? 44 GLY D N 1 ATOM 5268 C CA . GLY D 2 44 ? -10.196 -1.106 20.066 1.00 32.72 ? 44 GLY D CA 1 ATOM 5269 C C . GLY D 2 44 ? -9.187 -0.561 19.082 1.00 27.99 ? 44 GLY D C 1 ATOM 5270 O O . GLY D 2 44 ? -8.869 0.631 19.112 1.00 30.23 ? 44 GLY D O 1 ATOM 5271 N N . LEU D 2 45 ? -8.691 -1.434 18.207 1.00 24.86 ? 45 LEU D N 1 ATOM 5272 C CA . LEU D 2 45 ? -7.657 -1.073 17.238 1.00 21.07 ? 45 LEU D CA 1 ATOM 5273 C C . LEU D 2 45 ? -8.192 -0.315 16.025 1.00 22.39 ? 45 LEU D C 1 ATOM 5274 O O . LEU D 2 45 ? -9.145 -0.728 15.376 1.00 21.05 ? 45 LEU D O 1 ATOM 5275 C CB . LEU D 2 45 ? -6.904 -2.322 16.784 1.00 21.35 ? 45 LEU D CB 1 ATOM 5276 C CG . LEU D 2 45 ? -5.969 -2.932 17.832 1.00 25.42 ? 45 LEU D CG 1 ATOM 5277 C CD1 . LEU D 2 45 ? -5.625 -4.348 17.431 1.00 21.57 ? 45 LEU D CD1 1 ATOM 5278 C CD2 . LEU D 2 45 ? -4.709 -2.090 18.035 1.00 20.02 ? 45 LEU D CD2 1 ATOM 5279 N N . GLU D 2 46 ? -7.534 0.787 15.701 1.00 25.06 ? 46 GLU D N 1 ATOM 5280 C CA . GLU D 2 46 ? -8.059 1.711 14.713 1.00 27.04 ? 46 GLU D CA 1 ATOM 5281 C C . GLU D 2 46 ? -6.927 2.320 13.893 1.00 31.46 ? 46 GLU D C 1 ATOM 5282 O O . GLU D 2 46 ? -6.054 3.010 14.435 1.00 26.26 ? 46 GLU D O 1 ATOM 5283 C CB . GLU D 2 46 ? -8.829 2.807 15.449 1.00 25.78 ? 46 GLU D CB 1 ATOM 5284 C CG . GLU D 2 46 ? -9.685 3.703 14.594 1.00 30.06 ? 46 GLU D CG 1 ATOM 5285 C CD . GLU D 2 46 ? -10.612 4.573 15.444 1.00 40.69 ? 46 GLU D CD 1 ATOM 5286 O OE1 . GLU D 2 46 ? -10.370 4.703 16.675 1.00 36.89 ? 46 GLU D OE1 1 ATOM 5287 O OE2 . GLU D 2 46 ? -11.589 5.118 14.882 1.00 38.53 ? 46 GLU D OE2 1 ATOM 5288 N N . TRP D 2 47 ? -6.940 2.066 12.586 1.00 24.90 ? 47 TRP D N 1 ATOM 5289 C CA . TRP D 2 47 ? -5.939 2.629 11.698 1.00 19.16 ? 47 TRP D CA 1 ATOM 5290 C C . TRP D 2 47 ? -6.219 4.103 11.496 1.00 21.82 ? 47 TRP D C 1 ATOM 5291 O O . TRP D 2 47 ? -7.357 4.492 11.248 1.00 26.83 ? 47 TRP D O 1 ATOM 5292 C CB . TRP D 2 47 ? -5.968 1.899 10.368 1.00 25.19 ? 47 TRP D CB 1 ATOM 5293 C CG . TRP D 2 47 ? -4.972 2.388 9.351 1.00 21.85 ? 47 TRP D CG 1 ATOM 5294 C CD1 . TRP D 2 47 ? -3.646 2.044 9.252 1.00 21.23 ? 47 TRP D CD1 1 ATOM 5295 C CD2 . TRP D 2 47 ? -5.237 3.273 8.269 1.00 18.64 ? 47 TRP D CD2 1 ATOM 5296 N NE1 . TRP D 2 47 ? -3.075 2.678 8.177 1.00 23.93 ? 47 TRP D NE1 1 ATOM 5297 C CE2 . TRP D 2 47 ? -4.030 3.435 7.553 1.00 23.90 ? 47 TRP D CE2 1 ATOM 5298 C CE3 . TRP D 2 47 ? -6.379 3.944 7.829 1.00 20.73 ? 47 TRP D CE3 1 ATOM 5299 C CZ2 . TRP D 2 47 ? -3.934 4.248 6.418 1.00 26.71 ? 47 TRP D CZ2 1 ATOM 5300 C CZ3 . TRP D 2 47 ? -6.283 4.761 6.697 1.00 27.39 ? 47 TRP D CZ3 1 ATOM 5301 C CH2 . TRP D 2 47 ? -5.067 4.901 6.006 1.00 22.64 ? 47 TRP D CH2 1 ATOM 5302 N N . LEU D 2 48 ? -5.181 4.926 11.597 1.00 22.57 ? 48 LEU D N 1 ATOM 5303 C CA . LEU D 2 48 ? -5.372 6.371 11.614 1.00 24.14 ? 48 LEU D CA 1 ATOM 5304 C C . LEU D 2 48 ? -4.869 7.038 10.338 1.00 26.16 ? 48 LEU D C 1 ATOM 5305 O O . LEU D 2 48 ? -5.584 7.831 9.714 1.00 26.47 ? 48 LEU D O 1 ATOM 5306 C CB . LEU D 2 48 ? -4.695 6.988 12.845 1.00 23.61 ? 48 LEU D CB 1 ATOM 5307 C CG . LEU D 2 48 ? -5.286 6.647 14.213 1.00 21.12 ? 48 LEU D CG 1 ATOM 5308 C CD1 . LEU D 2 48 ? -4.497 7.316 15.322 1.00 20.85 ? 48 LEU D CD1 1 ATOM 5309 C CD2 . LEU D 2 48 ? -6.738 7.075 14.288 1.00 21.99 ? 48 LEU D CD2 1 ATOM 5310 N N . GLY D 2 49 ? -3.637 6.722 9.955 1.00 22.97 ? 49 GLY D N 1 ATOM 5311 C CA . GLY D 2 49 ? -3.034 7.343 8.795 1.00 22.81 ? 49 GLY D CA 1 ATOM 5312 C C . GLY D 2 49 ? -1.708 6.733 8.414 1.00 24.05 ? 49 GLY D C 1 ATOM 5313 O O . GLY D 2 49 ? -1.190 5.854 9.105 1.00 26.33 ? 49 GLY D O 1 ATOM 5314 N N . VAL D 2 50 ? -1.157 7.213 7.305 1.00 24.42 ? 50 VAL D N 1 ATOM 5315 C CA . VAL D 2 50 ? 0.143 6.772 6.823 1.00 18.47 ? 50 VAL D CA 1 ATOM 5316 C C . VAL D 2 50 ? 0.835 7.927 6.122 1.00 20.56 ? 50 VAL D C 1 ATOM 5317 O O . VAL D 2 50 ? 0.187 8.742 5.468 1.00 22.58 ? 50 VAL D O 1 ATOM 5318 C CB . VAL D 2 50 ? 0.013 5.557 5.849 1.00 23.42 ? 50 VAL D CB 1 ATOM 5319 C CG1 . VAL D 2 50 ? -1.002 5.841 4.736 1.00 21.18 ? 50 VAL D CG1 1 ATOM 5320 C CG2 . VAL D 2 50 ? 1.360 5.167 5.269 1.00 20.86 ? 50 VAL D CG2 1 ATOM 5321 N N . ILE D 2 51 ? 2.148 8.015 6.293 1.00 21.32 ? 51 ILE D N 1 ATOM 5322 C CA . ILE D 2 51 ? 2.975 8.841 5.431 1.00 20.67 ? 51 ILE D CA 1 ATOM 5323 C C . ILE D 2 51 ? 3.896 7.914 4.640 1.00 21.25 ? 51 ILE D C 1 ATOM 5324 O O . ILE D 2 51 ? 4.642 7.114 5.216 1.00 22.80 ? 51 ILE D O 1 ATOM 5325 C CB . ILE D 2 51 ? 3.762 9.918 6.208 1.00 22.18 ? 51 ILE D CB 1 ATOM 5326 C CG1 . ILE D 2 51 ? 4.519 10.824 5.232 1.00 23.34 ? 51 ILE D CG1 1 ATOM 5327 C CG2 . ILE D 2 51 ? 4.725 9.295 7.203 1.00 17.87 ? 51 ILE D CG2 1 ATOM 5328 C CD1 . ILE D 2 51 ? 4.999 12.095 5.853 1.00 19.22 ? 51 ILE D CD1 1 ATOM 5329 N N . TRP D 2 52 ? 3.800 7.994 3.318 1.00 22.72 ? 52 TRP D N 1 ATOM 5330 C CA . TRP D 2 52 ? 4.542 7.099 2.427 1.00 23.18 ? 52 TRP D CA 1 ATOM 5331 C C . TRP D 2 52 ? 5.954 7.598 2.157 1.00 25.35 ? 52 TRP D C 1 ATOM 5332 O O . TRP D 2 52 ? 6.290 8.733 2.478 1.00 24.58 ? 52 TRP D O 1 ATOM 5333 C CB . TRP D 2 52 ? 3.804 6.923 1.098 1.00 20.58 ? 52 TRP D CB 1 ATOM 5334 C CG . TRP D 2 52 ? 2.391 6.420 1.241 1.00 30.58 ? 52 TRP D CG 1 ATOM 5335 C CD1 . TRP D 2 52 ? 1.244 7.156 1.128 1.00 26.14 ? 52 TRP D CD1 1 ATOM 5336 C CD2 . TRP D 2 52 ? 1.974 5.075 1.523 1.00 28.69 ? 52 TRP D CD2 1 ATOM 5337 N NE1 . TRP D 2 52 ? 0.150 6.359 1.327 1.00 26.33 ? 52 TRP D NE1 1 ATOM 5338 C CE2 . TRP D 2 52 ? 0.565 5.076 1.568 1.00 27.40 ? 52 TRP D CE2 1 ATOM 5339 C CE3 . TRP D 2 52 ? 2.655 3.873 1.746 1.00 28.80 ? 52 TRP D CE3 1 ATOM 5340 C CZ2 . TRP D 2 52 ? -0.180 3.923 1.818 1.00 30.74 ? 52 TRP D CZ2 1 ATOM 5341 C CZ3 . TRP D 2 52 ? 1.913 2.724 1.995 1.00 29.38 ? 52 TRP D CZ3 1 ATOM 5342 C CH2 . TRP D 2 52 ? 0.509 2.760 2.030 1.00 27.46 ? 52 TRP D CH2 1 ATOM 5343 N N . SER D 2 53 ? 6.765 6.735 1.554 1.00 29.74 ? 53 SER D N 1 ATOM 5344 C CA . SER D 2 53 ? 8.162 7.026 1.242 1.00 27.31 ? 53 SER D CA 1 ATOM 5345 C C . SER D 2 53 ? 8.384 8.399 0.637 1.00 32.57 ? 53 SER D C 1 ATOM 5346 O O . SER D 2 53 ? 9.249 9.145 1.091 1.00 32.81 ? 53 SER D O 1 ATOM 5347 C CB . SER D 2 53 ? 8.711 5.966 0.293 1.00 30.68 ? 53 SER D CB 1 ATOM 5348 O OG . SER D 2 53 ? 8.915 4.746 0.983 1.00 35.67 ? 53 SER D OG 1 ATOM 5349 N N . GLY D 2 54 ? 7.594 8.728 -0.383 1.00 28.45 ? 54 GLY D N 1 ATOM 5350 C CA . GLY D 2 54 ? 7.724 9.996 -1.075 1.00 24.28 ? 54 GLY D CA 1 ATOM 5351 C C . GLY D 2 54 ? 7.043 11.192 -0.426 1.00 33.19 ? 54 GLY D C 1 ATOM 5352 O O . GLY D 2 54 ? 6.998 12.274 -1.011 1.00 35.82 ? 54 GLY D O 1 ATOM 5353 N N . GLY D 2 55 ? 6.502 11.015 0.774 1.00 30.45 ? 55 GLY D N 1 ATOM 5354 C CA . GLY D 2 55 ? 5.931 12.139 1.494 1.00 20.61 ? 55 GLY D CA 1 ATOM 5355 C C . GLY D 2 55 ? 4.424 12.287 1.401 1.00 23.81 ? 55 GLY D C 1 ATOM 5356 O O . GLY D 2 55 ? 3.853 13.088 2.133 1.00 26.72 ? 55 GLY D O 1 ATOM 5357 N N . ASN D 2 56 ? 3.777 11.543 0.503 1.00 25.56 ? 56 ASN D N 1 ATOM 5358 C CA . ASN D 2 56 ? 2.316 11.504 0.452 1.00 21.63 ? 56 ASN D CA 1 ATOM 5359 C C . ASN D 2 56 ? 1.720 10.978 1.762 1.00 31.97 ? 56 ASN D C 1 ATOM 5360 O O . ASN D 2 56 ? 2.334 10.147 2.448 1.00 27.08 ? 56 ASN D O 1 ATOM 5361 C CB . ASN D 2 56 ? 1.831 10.604 -0.687 1.00 33.19 ? 56 ASN D CB 1 ATOM 5362 C CG . ASN D 2 56 ? 1.906 11.271 -2.050 1.00 33.90 ? 56 ASN D CG 1 ATOM 5363 O OD1 . ASN D 2 56 ? 1.773 12.488 -2.178 1.00 29.79 ? 56 ASN D OD1 1 ATOM 5364 N ND2 . ASN D 2 56 ? 2.112 10.461 -3.082 1.00 32.55 ? 56 ASN D ND2 1 ATOM 5365 N N . THR D 2 57 ? 0.524 11.452 2.108 1.00 23.94 ? 57 THR D N 1 ATOM 5366 C CA . THR D 2 57 ? -0.164 10.952 3.290 1.00 20.75 ? 57 THR D CA 1 ATOM 5367 C C . THR D 2 57 ? -1.591 10.574 2.969 1.00 27.22 ? 57 THR D C 1 ATOM 5368 O O . THR D 2 57 ? -2.248 11.231 2.166 1.00 29.63 ? 57 THR D O 1 ATOM 5369 C CB . THR D 2 57 ? -0.229 12.001 4.412 1.00 24.82 ? 57 THR D CB 1 ATOM 5370 O OG1 . THR D 2 57 ? -0.833 13.198 3.904 1.00 30.70 ? 57 THR D OG1 1 ATOM 5371 C CG2 . THR D 2 57 ? 1.169 12.299 4.967 1.00 22.99 ? 57 THR D CG2 1 ATOM 5372 N N . ASP D 2 58 ? -2.058 9.505 3.602 1.00 25.81 ? 58 ASP D N 1 ATOM 5373 C CA . ASP D 2 58 ? -3.465 9.161 3.616 1.00 18.05 ? 58 ASP D CA 1 ATOM 5374 C C . ASP D 2 58 ? -3.922 9.217 5.063 1.00 30.94 ? 58 ASP D C 1 ATOM 5375 O O . ASP D 2 58 ? -3.175 8.833 5.964 1.00 25.71 ? 58 ASP D O 1 ATOM 5376 C CB . ASP D 2 58 ? -3.674 7.738 3.103 1.00 21.27 ? 58 ASP D CB 1 ATOM 5377 C CG . ASP D 2 58 ? -3.387 7.593 1.623 1.00 33.75 ? 58 ASP D CG 1 ATOM 5378 O OD1 . ASP D 2 58 ? -3.850 8.450 0.829 1.00 25.64 ? 58 ASP D OD1 1 ATOM 5379 O OD2 . ASP D 2 58 ? -2.703 6.605 1.267 1.00 26.94 ? 58 ASP D OD2 1 ATOM 5380 N N . TYR D 2 59 ? -5.145 9.686 5.289 1.00 26.82 ? 59 TYR D N 1 ATOM 5381 C CA . TYR D 2 59 ? -5.727 9.668 6.627 1.00 27.21 ? 59 TYR D CA 1 ATOM 5382 C C . TYR D 2 59 ? -7.054 8.909 6.630 1.00 29.09 ? 59 TYR D C 1 ATOM 5383 O O . TYR D 2 59 ? -7.839 8.992 5.676 1.00 22.28 ? 59 TYR D O 1 ATOM 5384 C CB . TYR D 2 59 ? -5.940 11.095 7.136 1.00 27.59 ? 59 TYR D CB 1 ATOM 5385 C CG . TYR D 2 59 ? -4.687 11.932 7.126 1.00 24.69 ? 59 TYR D CG 1 ATOM 5386 C CD1 . TYR D 2 59 ? -3.514 11.475 7.717 1.00 31.79 ? 59 TYR D CD1 1 ATOM 5387 C CD2 . TYR D 2 59 ? -4.669 13.177 6.517 1.00 24.99 ? 59 TYR D CD2 1 ATOM 5388 C CE1 . TYR D 2 59 ? -2.354 12.247 7.702 1.00 28.81 ? 59 TYR D CE1 1 ATOM 5389 C CE2 . TYR D 2 59 ? -3.528 13.949 6.502 1.00 30.15 ? 59 TYR D CE2 1 ATOM 5390 C CZ . TYR D 2 59 ? -2.373 13.482 7.095 1.00 28.29 ? 59 TYR D CZ 1 ATOM 5391 O OH . TYR D 2 59 ? -1.239 14.257 7.071 1.00 32.54 ? 59 TYR D OH 1 ATOM 5392 N N . ASN D 2 60 ? -7.310 8.153 7.690 1.00 24.36 ? 60 ASN D N 1 ATOM 5393 C CA . ASN D 2 60 ? -8.604 7.504 7.784 1.00 24.91 ? 60 ASN D CA 1 ATOM 5394 C C . ASN D 2 60 ? -9.684 8.575 7.883 1.00 32.49 ? 60 ASN D C 1 ATOM 5395 O O . ASN D 2 60 ? -9.528 9.563 8.607 1.00 27.71 ? 60 ASN D O 1 ATOM 5396 C CB . ASN D 2 60 ? -8.670 6.539 8.960 1.00 29.68 ? 60 ASN D CB 1 ATOM 5397 C CG . ASN D 2 60 ? -9.824 5.570 8.837 1.00 27.60 ? 60 ASN D CG 1 ATOM 5398 O OD1 . ASN D 2 60 ? -10.713 5.756 8.008 1.00 20.51 ? 60 ASN D OD1 1 ATOM 5399 N ND2 . ASN D 2 60 ? -9.817 4.532 9.659 1.00 19.70 ? 60 ASN D ND2 1 ATOM 5400 N N . THR D 2 61 ? -10.758 8.374 7.123 1.00 31.85 ? 61 THR D N 1 ATOM 5401 C CA . THR D 2 61 ? -11.812 9.373 6.925 1.00 29.93 ? 61 THR D CA 1 ATOM 5402 C C . THR D 2 61 ? -12.249 10.198 8.158 1.00 32.05 ? 61 THR D C 1 ATOM 5403 O O . THR D 2 61 ? -12.272 11.427 8.093 1.00 27.91 ? 61 THR D O 1 ATOM 5404 C CB . THR D 2 61 ? -13.024 8.753 6.204 1.00 27.86 ? 61 THR D CB 1 ATOM 5405 O OG1 . THR D 2 61 ? -12.674 8.509 4.839 1.00 37.12 ? 61 THR D OG1 1 ATOM 5406 C CG2 . THR D 2 61 ? -14.219 9.689 6.246 1.00 27.97 ? 61 THR D CG2 1 ATOM 5407 N N . PRO D 2 62 ? -12.560 9.542 9.293 1.00 31.21 ? 62 PRO D N 1 ATOM 5408 C CA . PRO D 2 62 ? -12.983 10.377 10.425 1.00 28.44 ? 62 PRO D CA 1 ATOM 5409 C C . PRO D 2 62 ? -11.859 11.204 11.045 1.00 27.51 ? 62 PRO D C 1 ATOM 5410 O O . PRO D 2 62 ? -12.096 11.844 12.061 1.00 37.89 ? 62 PRO D O 1 ATOM 5411 C CB . PRO D 2 62 ? -13.495 9.356 11.437 1.00 29.55 ? 62 PRO D CB 1 ATOM 5412 C CG . PRO D 2 62 ? -12.751 8.120 11.126 1.00 31.32 ? 62 PRO D CG 1 ATOM 5413 C CD . PRO D 2 62 ? -12.575 8.107 9.637 1.00 30.12 ? 62 PRO D CD 1 ATOM 5414 N N . PHE D 2 63 ? -10.671 11.218 10.452 1.00 23.47 ? 63 PHE D N 1 ATOM 5415 C CA . PHE D 2 63 ? -9.582 11.997 11.020 1.00 22.61 ? 63 PHE D CA 1 ATOM 5416 C C . PHE D 2 63 ? -8.998 13.018 10.047 1.00 32.69 ? 63 PHE D C 1 ATOM 5417 O O . PHE D 2 63 ? -8.190 13.862 10.444 1.00 33.92 ? 63 PHE D O 1 ATOM 5418 C CB . PHE D 2 63 ? -8.498 11.069 11.573 1.00 20.78 ? 63 PHE D CB 1 ATOM 5419 C CG . PHE D 2 63 ? -9.006 10.124 12.631 1.00 31.68 ? 63 PHE D CG 1 ATOM 5420 C CD1 . PHE D 2 63 ? -9.483 8.866 12.294 1.00 25.64 ? 63 PHE D CD1 1 ATOM 5421 C CD2 . PHE D 2 63 ? -9.032 10.506 13.963 1.00 26.73 ? 63 PHE D CD2 1 ATOM 5422 C CE1 . PHE D 2 63 ? -9.966 8.007 13.267 1.00 23.57 ? 63 PHE D CE1 1 ATOM 5423 C CE2 . PHE D 2 63 ? -9.506 9.650 14.930 1.00 27.38 ? 63 PHE D CE2 1 ATOM 5424 C CZ . PHE D 2 63 ? -9.975 8.396 14.575 1.00 26.48 ? 63 PHE D CZ 1 ATOM 5425 N N . THR D 2 64 ? -9.445 12.957 8.792 1.00 32.83 ? 64 THR D N 1 ATOM 5426 C CA . THR D 2 64 ? -8.881 13.759 7.705 1.00 26.75 ? 64 THR D CA 1 ATOM 5427 C C . THR D 2 64 ? -8.743 15.244 8.030 1.00 32.44 ? 64 THR D C 1 ATOM 5428 O O . THR D 2 64 ? -7.779 15.888 7.616 1.00 40.29 ? 64 THR D O 1 ATOM 5429 C CB . THR D 2 64 ? -9.657 13.570 6.371 1.00 29.86 ? 64 THR D CB 1 ATOM 5430 O OG1 . THR D 2 64 ? -11.064 13.530 6.622 1.00 40.32 ? 64 THR D OG1 1 ATOM 5431 C CG2 . THR D 2 64 ? -9.260 12.263 5.698 1.00 27.95 ? 64 THR D CG2 1 ATOM 5432 N N . SER D 2 65 ? -9.677 15.778 8.807 1.00 36.71 ? 65 SER D N 1 ATOM 5433 C CA . SER D 2 65 ? -9.679 17.204 9.088 1.00 33.77 ? 65 SER D CA 1 ATOM 5434 C C . SER D 2 65 ? -9.054 17.578 10.433 1.00 34.07 ? 65 SER D C 1 ATOM 5435 O O . SER D 2 65 ? -9.171 18.719 10.878 1.00 33.80 ? 65 SER D O 1 ATOM 5436 C CB . SER D 2 65 ? -11.100 17.751 9.022 1.00 32.82 ? 65 SER D CB 1 ATOM 5437 O OG . SER D 2 65 ? -11.853 17.297 10.126 1.00 42.17 ? 65 SER D OG 1 ATOM 5438 N N . ARG D 2 66 ? -8.387 16.642 11.094 1.00 37.25 ? 66 ARG D N 1 ATOM 5439 C CA . ARG D 2 66 ? -7.746 17.003 12.353 1.00 38.75 ? 66 ARG D CA 1 ATOM 5440 C C . ARG D 2 66 ? -6.422 16.310 12.586 1.00 28.32 ? 66 ARG D C 1 ATOM 5441 O O . ARG D 2 66 ? -5.863 16.366 13.680 1.00 29.83 ? 66 ARG D O 1 ATOM 5442 C CB . ARG D 2 66 ? -8.696 16.777 13.531 1.00 32.38 ? 66 ARG D CB 1 ATOM 5443 C CG . ARG D 2 66 ? -8.982 15.330 13.897 1.00 32.48 ? 66 ARG D CG 1 ATOM 5444 C CD . ARG D 2 66 ? -10.075 15.338 14.958 1.00 40.65 ? 66 ARG D CD 1 ATOM 5445 N NE . ARG D 2 66 ? -10.298 14.044 15.575 1.00 34.48 ? 66 ARG D NE 1 ATOM 5446 C CZ . ARG D 2 66 ? -10.063 13.782 16.856 1.00 38.30 ? 66 ARG D CZ 1 ATOM 5447 N NH1 . ARG D 2 66 ? -9.597 14.731 17.660 1.00 34.30 ? 66 ARG D NH1 1 ATOM 5448 N NH2 . ARG D 2 66 ? -10.294 12.567 17.333 1.00 43.79 ? 66 ARG D NH2 1 ATOM 5449 N N . LEU D 2 67 ? -5.909 15.677 11.545 1.00 27.75 ? 67 LEU D N 1 ATOM 5450 C CA . LEU D 2 67 ? -4.694 14.895 11.674 1.00 28.05 ? 67 LEU D CA 1 ATOM 5451 C C . LEU D 2 67 ? -3.664 15.337 10.647 1.00 30.50 ? 67 LEU D C 1 ATOM 5452 O O . LEU D 2 67 ? -3.991 15.635 9.496 1.00 36.80 ? 67 LEU D O 1 ATOM 5453 C CB . LEU D 2 67 ? -5.026 13.418 11.501 1.00 26.92 ? 67 LEU D CB 1 ATOM 5454 C CG . LEU D 2 67 ? -3.906 12.394 11.511 1.00 30.65 ? 67 LEU D CG 1 ATOM 5455 C CD1 . LEU D 2 67 ? -3.105 12.534 12.783 1.00 30.91 ? 67 LEU D CD1 1 ATOM 5456 C CD2 . LEU D 2 67 ? -4.509 11.018 11.403 1.00 27.77 ? 67 LEU D CD2 1 ATOM 5457 N N . SER D 2 68 ? -2.413 15.407 11.064 1.00 25.25 ? 68 SER D N 1 ATOM 5458 C CA . SER D 2 68 ? -1.364 15.700 10.123 1.00 23.46 ? 68 SER D CA 1 ATOM 5459 C C . SER D 2 68 ? -0.150 14.839 10.452 1.00 30.67 ? 68 SER D C 1 ATOM 5460 O O . SER D 2 68 ? 0.214 14.670 11.620 1.00 33.82 ? 68 SER D O 1 ATOM 5461 C CB . SER D 2 68 ? -1.026 17.189 10.143 1.00 25.07 ? 68 SER D CB 1 ATOM 5462 O OG . SER D 2 68 ? 0.071 17.446 10.993 1.00 37.77 ? 68 SER D OG 1 ATOM 5463 N N . ILE D 2 69 ? 0.454 14.265 9.420 1.00 21.44 ? 69 ILE D N 1 ATOM 5464 C CA . ILE D 2 69 ? 1.615 13.430 9.598 1.00 18.23 ? 69 ILE D CA 1 ATOM 5465 C C . ILE D 2 69 ? 2.721 13.952 8.710 1.00 24.55 ? 69 ILE D C 1 ATOM 5466 O O . ILE D 2 69 ? 2.553 14.086 7.488 1.00 27.27 ? 69 ILE D O 1 ATOM 5467 C CB . ILE D 2 69 ? 1.317 11.973 9.240 1.00 22.85 ? 69 ILE D CB 1 ATOM 5468 C CG1 . ILE D 2 69 ? 0.131 11.452 10.056 1.00 23.62 ? 69 ILE D CG1 1 ATOM 5469 C CG2 . ILE D 2 69 ? 2.551 11.107 9.451 1.00 18.40 ? 69 ILE D CG2 1 ATOM 5470 C CD1 . ILE D 2 69 ? -0.196 10.003 9.793 1.00 20.71 ? 69 ILE D CD1 1 ATOM 5471 N N . ASN D 2 70 ? 3.853 14.259 9.329 1.00 25.24 ? 70 ASN D N 1 ATOM 5472 C CA . ASN D 2 70 ? 5.001 14.791 8.613 1.00 25.10 ? 70 ASN D CA 1 ATOM 5473 C C . ASN D 2 70 ? 6.235 13.983 8.950 1.00 31.10 ? 70 ASN D C 1 ATOM 5474 O O . ASN D 2 70 ? 6.211 13.158 9.867 1.00 31.18 ? 70 ASN D O 1 ATOM 5475 C CB . ASN D 2 70 ? 5.215 16.262 8.976 1.00 25.79 ? 70 ASN D CB 1 ATOM 5476 C CG . ASN D 2 70 ? 4.187 17.164 8.332 1.00 32.61 ? 70 ASN D CG 1 ATOM 5477 O OD1 . ASN D 2 70 ? 4.306 17.501 7.153 1.00 50.89 ? 70 ASN D OD1 1 ATOM 5478 N ND2 . ASN D 2 70 ? 3.151 17.535 9.084 1.00 28.78 ? 70 ASN D ND2 1 ATOM 5479 N N . LYS D 2 71 ? 7.316 14.211 8.215 1.00 31.83 ? 71 LYS D N 1 ATOM 5480 C CA . LYS D 2 71 ? 8.571 13.559 8.546 1.00 25.30 ? 71 LYS D CA 1 ATOM 5481 C C . LYS D 2 71 ? 9.788 14.371 8.142 1.00 28.97 ? 71 LYS D C 1 ATOM 5482 O O . LYS D 2 71 ? 9.697 15.343 7.400 1.00 25.01 ? 71 LYS D O 1 ATOM 5483 C CB . LYS D 2 71 ? 8.653 12.179 7.901 1.00 32.00 ? 71 LYS D CB 1 ATOM 5484 C CG . LYS D 2 71 ? 8.523 12.189 6.398 1.00 27.41 ? 71 LYS D CG 1 ATOM 5485 C CD . LYS D 2 71 ? 8.603 10.779 5.840 1.00 35.30 ? 71 LYS D CD 1 ATOM 5486 C CE . LYS D 2 71 ? 8.641 10.783 4.314 1.00 28.96 ? 71 LYS D CE 1 ATOM 5487 N NZ . LYS D 2 71 ? 9.090 9.476 3.828 1.00 26.65 ? 71 LYS D NZ 1 ATOM 5488 N N . ASP D 2 72 ? 10.928 13.953 8.672 1.00 29.80 ? 72 ASP D N 1 ATOM 5489 C CA . ASP D 2 72 ? 12.220 14.488 8.309 1.00 27.76 ? 72 ASP D CA 1 ATOM 5490 C C . ASP D 2 72 ? 13.026 13.249 7.971 1.00 36.51 ? 72 ASP D C 1 ATOM 5491 O O . ASP D 2 72 ? 13.424 12.502 8.872 1.00 32.60 ? 72 ASP D O 1 ATOM 5492 C CB . ASP D 2 72 ? 12.827 15.226 9.503 1.00 35.97 ? 72 ASP D CB 1 ATOM 5493 C CG . ASP D 2 72 ? 14.219 15.777 9.221 1.00 42.74 ? 72 ASP D CG 1 ATOM 5494 O OD1 . ASP D 2 72 ? 15.029 15.097 8.558 1.00 36.86 ? 72 ASP D OD1 1 ATOM 5495 O OD2 . ASP D 2 72 ? 14.514 16.901 9.683 1.00 51.46 ? 72 ASP D OD2 1 ATOM 5496 N N . ASN D 2 73 ? 13.254 13.017 6.679 1.00 35.88 ? 73 ASN D N 1 ATOM 5497 C CA . ASN D 2 73 ? 13.952 11.808 6.248 1.00 36.30 ? 73 ASN D CA 1 ATOM 5498 C C . ASN D 2 73 ? 15.343 11.682 6.851 1.00 37.98 ? 73 ASN D C 1 ATOM 5499 O O . ASN D 2 73 ? 15.751 10.594 7.255 1.00 36.80 ? 73 ASN D O 1 ATOM 5500 C CB . ASN D 2 73 ? 14.029 11.730 4.722 1.00 35.73 ? 73 ASN D CB 1 ATOM 5501 C CG . ASN D 2 73 ? 12.697 11.431 4.093 1.00 36.39 ? 73 ASN D CG 1 ATOM 5502 O OD1 . ASN D 2 73 ? 11.931 10.618 4.603 1.00 43.78 ? 73 ASN D OD1 1 ATOM 5503 N ND2 . ASN D 2 73 ? 12.404 12.090 2.980 1.00 33.70 ? 73 ASN D ND2 1 ATOM 5504 N N . SER D 2 74 ? 16.057 12.805 6.926 1.00 36.82 ? 74 SER D N 1 ATOM 5505 C CA . SER D 2 74 ? 17.439 12.825 7.427 1.00 34.80 ? 74 SER D CA 1 ATOM 5506 C C . SER D 2 74 ? 17.545 12.470 8.909 1.00 36.47 ? 74 SER D C 1 ATOM 5507 O O . SER D 2 74 ? 18.454 11.735 9.311 1.00 30.31 ? 74 SER D O 1 ATOM 5508 C CB . SER D 2 74 ? 18.104 14.178 7.149 1.00 36.30 ? 74 SER D CB 1 ATOM 5509 O OG . SER D 2 74 ? 17.430 15.245 7.790 1.00 46.27 ? 74 SER D OG 1 ATOM 5510 N N . LYS D 2 75 ? 16.614 12.988 9.713 1.00 36.02 ? 75 LYS D N 1 ATOM 5511 C CA . LYS D 2 75 ? 16.596 12.708 11.151 1.00 33.18 ? 75 LYS D CA 1 ATOM 5512 C C . LYS D 2 75 ? 15.916 11.383 11.506 1.00 31.46 ? 75 LYS D C 1 ATOM 5513 O O . LYS D 2 75 ? 15.868 11.008 12.671 1.00 34.03 ? 75 LYS D O 1 ATOM 5514 C CB . LYS D 2 75 ? 15.970 13.867 11.941 1.00 35.66 ? 75 LYS D CB 1 ATOM 5515 C CG . LYS D 2 75 ? 16.688 15.200 11.731 1.00 38.45 ? 75 LYS D CG 1 ATOM 5516 C CD . LYS D 2 75 ? 16.134 16.302 12.618 1.00 41.35 ? 75 LYS D CD 1 ATOM 5517 C CE . LYS D 2 75 ? 14.608 16.298 12.633 1.00 56.83 ? 75 LYS D CE 1 ATOM 5518 N NZ . LYS D 2 75 ? 14.008 17.589 13.095 1.00 52.57 ? 75 LYS D NZ 1 ATOM 5519 N N . SER D 2 76 ? 15.406 10.674 10.503 1.00 33.73 ? 76 SER D N 1 ATOM 5520 C CA . SER D 2 76 ? 14.800 9.359 10.704 1.00 26.75 ? 76 SER D CA 1 ATOM 5521 C C . SER D 2 76 ? 13.586 9.465 11.630 1.00 25.57 ? 76 SER D C 1 ATOM 5522 O O . SER D 2 76 ? 13.269 8.532 12.375 1.00 21.97 ? 76 SER D O 1 ATOM 5523 C CB . SER D 2 76 ? 15.831 8.377 11.272 1.00 24.94 ? 76 SER D CB 1 ATOM 5524 O OG . SER D 2 76 ? 15.843 7.158 10.551 1.00 36.90 ? 76 SER D OG 1 ATOM 5525 N N . GLN D 2 77 ? 12.915 10.614 11.576 1.00 23.75 ? 77 GLN D N 1 ATOM 5526 C CA . GLN D 2 77 ? 11.780 10.892 12.449 1.00 28.70 ? 77 GLN D CA 1 ATOM 5527 C C . GLN D 2 77 ? 10.470 11.184 11.715 1.00 27.50 ? 77 GLN D C 1 ATOM 5528 O O . GLN D 2 77 ? 10.444 11.948 10.757 1.00 31.97 ? 77 GLN D O 1 ATOM 5529 C CB . GLN D 2 77 ? 12.105 12.076 13.355 1.00 32.67 ? 77 GLN D CB 1 ATOM 5530 C CG . GLN D 2 77 ? 13.199 11.803 14.364 1.00 31.49 ? 77 GLN D CG 1 ATOM 5531 C CD . GLN D 2 77 ? 13.435 12.990 15.273 1.00 36.47 ? 77 GLN D CD 1 ATOM 5532 O OE1 . GLN D 2 77 ? 13.455 14.138 14.825 1.00 32.30 ? 77 GLN D OE1 1 ATOM 5533 N NE2 . GLN D 2 77 ? 13.602 12.721 16.562 1.00 41.07 ? 77 GLN D NE2 1 ATOM 5534 N N . VAL D 2 78 ? 9.384 10.591 12.204 1.00 27.68 ? 78 VAL D N 1 ATOM 5535 C CA . VAL D 2 78 ? 8.025 10.867 11.725 1.00 25.90 ? 78 VAL D CA 1 ATOM 5536 C C . VAL D 2 78 ? 7.214 11.621 12.784 1.00 26.97 ? 78 VAL D C 1 ATOM 5537 O O . VAL D 2 78 ? 7.262 11.275 13.964 1.00 30.27 ? 78 VAL D O 1 ATOM 5538 C CB . VAL D 2 78 ? 7.277 9.551 11.371 1.00 26.59 ? 78 VAL D CB 1 ATOM 5539 C CG1 . VAL D 2 78 ? 5.834 9.841 10.969 1.00 19.45 ? 78 VAL D CG1 1 ATOM 5540 C CG2 . VAL D 2 78 ? 8.010 8.801 10.254 1.00 19.33 ? 78 VAL D CG2 1 ATOM 5541 N N . PHE D 2 79 ? 6.465 12.639 12.365 1.00 26.13 ? 79 PHE D N 1 ATOM 5542 C CA . PHE D 2 79 ? 5.707 13.472 13.303 1.00 24.88 ? 79 PHE D CA 1 ATOM 5543 C C . PHE D 2 79 ? 4.178 13.346 13.161 1.00 31.18 ? 79 PHE D C 1 ATOM 5544 O O . PHE D 2 79 ? 3.602 13.657 12.115 1.00 29.74 ? 79 PHE D O 1 ATOM 5545 C CB . PHE D 2 79 ? 6.115 14.938 13.160 1.00 21.40 ? 79 PHE D CB 1 ATOM 5546 C CG . PHE D 2 79 ? 7.603 15.151 13.064 1.00 28.23 ? 79 PHE D CG 1 ATOM 5547 C CD1 . PHE D 2 79 ? 8.197 15.449 11.847 1.00 26.30 ? 79 PHE D CD1 1 ATOM 5548 C CD2 . PHE D 2 79 ? 8.410 15.050 14.191 1.00 34.95 ? 79 PHE D CD2 1 ATOM 5549 C CE1 . PHE D 2 79 ? 9.557 15.646 11.756 1.00 33.07 ? 79 PHE D CE1 1 ATOM 5550 C CE2 . PHE D 2 79 ? 9.776 15.246 14.106 1.00 26.99 ? 79 PHE D CE2 1 ATOM 5551 C CZ . PHE D 2 79 ? 10.351 15.546 12.887 1.00 35.97 ? 79 PHE D CZ 1 ATOM 5552 N N . PHE D 2 80 ? 3.535 12.901 14.235 1.00 22.86 ? 80 PHE D N 1 ATOM 5553 C CA . PHE D 2 80 ? 2.096 12.710 14.280 1.00 23.31 ? 80 PHE D CA 1 ATOM 5554 C C . PHE D 2 80 ? 1.511 13.856 15.073 1.00 28.50 ? 80 PHE D C 1 ATOM 5555 O O . PHE D 2 80 ? 1.960 14.134 16.182 1.00 33.15 ? 80 PHE D O 1 ATOM 5556 C CB . PHE D 2 80 ? 1.798 11.389 14.987 1.00 25.02 ? 80 PHE D CB 1 ATOM 5557 C CG . PHE D 2 80 ? 0.335 11.109 15.208 1.00 25.16 ? 80 PHE D CG 1 ATOM 5558 C CD1 . PHE D 2 80 ? -0.373 10.334 14.310 1.00 22.02 ? 80 PHE D CD1 1 ATOM 5559 C CD2 . PHE D 2 80 ? -0.319 11.573 16.349 1.00 29.18 ? 80 PHE D CD2 1 ATOM 5560 C CE1 . PHE D 2 80 ? -1.711 10.043 14.531 1.00 25.94 ? 80 PHE D CE1 1 ATOM 5561 C CE2 . PHE D 2 80 ? -1.665 11.290 16.572 1.00 22.74 ? 80 PHE D CE2 1 ATOM 5562 C CZ . PHE D 2 80 ? -2.356 10.526 15.668 1.00 24.58 ? 80 PHE D CZ 1 ATOM 5563 N N . LYS D 2 81 ? 0.508 14.525 14.516 1.00 26.78 ? 81 LYS D N 1 ATOM 5564 C CA . LYS D 2 81 ? -0.164 15.592 15.240 1.00 27.85 ? 81 LYS D CA 1 ATOM 5565 C C . LYS D 2 81 ? -1.674 15.507 15.030 1.00 32.58 ? 81 LYS D C 1 ATOM 5566 O O . LYS D 2 81 ? -2.133 15.345 13.897 1.00 31.63 ? 81 LYS D O 1 ATOM 5567 C CB . LYS D 2 81 ? 0.395 16.956 14.834 1.00 25.67 ? 81 LYS D CB 1 ATOM 5568 C CG . LYS D 2 81 ? -0.207 18.136 15.589 1.00 30.79 ? 81 LYS D CG 1 ATOM 5569 C CD . LYS D 2 81 ? 0.502 19.444 15.247 1.00 30.95 ? 81 LYS D CD 1 ATOM 5570 C CE . LYS D 2 81 ? -0.462 20.626 15.156 1.00 42.22 ? 81 LYS D CE 1 ATOM 5571 N NZ . LYS D 2 81 ? -1.074 21.019 16.466 1.00 31.84 ? 81 LYS D NZ 1 ATOM 5572 N N . MET D 2 82 ? -2.438 15.583 16.122 1.00 27.13 ? 82 MET D N 1 ATOM 5573 C CA . MET D 2 82 ? -3.894 15.494 16.047 1.00 28.85 ? 82 MET D CA 1 ATOM 5574 C C . MET D 2 82 ? -4.582 16.581 16.865 1.00 33.93 ? 82 MET D C 1 ATOM 5575 O O . MET D 2 82 ? -4.288 16.772 18.036 1.00 40.78 ? 82 MET D O 1 ATOM 5576 C CB . MET D 2 82 ? -4.396 14.118 16.479 1.00 26.28 ? 82 MET D CB 1 ATOM 5577 C CG . MET D 2 82 ? -5.895 13.937 16.290 1.00 27.54 ? 82 MET D CG 1 ATOM 5578 S SD . MET D 2 82 ? -6.412 12.210 16.390 1.00 35.61 ? 82 MET D SD 1 ATOM 5579 C CE . MET D 2 82 ? -6.963 12.095 18.095 1.00 30.87 ? 82 MET D CE 1 ATOM 5580 N N . ASN D 2 83 ? -5.521 17.276 16.239 1.00 40.18 ? 83 ASN D N 1 ATOM 5581 C CA . ASN D 2 83 ? -6.118 18.466 16.826 1.00 38.12 ? 83 ASN D CA 1 ATOM 5582 C C . ASN D 2 83 ? -7.418 18.209 17.577 1.00 35.61 ? 83 ASN D C 1 ATOM 5583 O O . ASN D 2 83 ? -8.147 17.248 17.297 1.00 28.57 ? 83 ASN D O 1 ATOM 5584 C CB . ASN D 2 83 ? -6.362 19.509 15.733 1.00 34.59 ? 83 ASN D CB 1 ATOM 5585 C CG . ASN D 2 83 ? -5.077 19.951 15.055 1.00 47.76 ? 83 ASN D CG 1 ATOM 5586 O OD1 . ASN D 2 83 ? -4.026 20.064 15.695 1.00 45.92 ? 83 ASN D OD1 1 ATOM 5587 N ND2 . ASN D 2 83 ? -5.154 20.203 13.751 1.00 54.27 ? 83 ASN D ND2 1 ATOM 5588 N N . SER D 2 84 ? -7.697 19.099 18.524 1.00 29.71 ? 84 SER D N 1 ATOM 5589 C CA . SER D 2 84 ? -8.954 19.108 19.259 1.00 42.14 ? 84 SER D CA 1 ATOM 5590 C C . SER D 2 84 ? -9.315 17.753 19.844 1.00 41.13 ? 84 SER D C 1 ATOM 5591 O O . SER D 2 84 ? -10.280 17.120 19.412 1.00 40.99 ? 84 SER D O 1 ATOM 5592 C CB . SER D 2 84 ? -10.087 19.620 18.374 1.00 45.52 ? 84 SER D CB 1 ATOM 5593 O OG . SER D 2 84 ? -9.967 21.018 18.181 1.00 50.66 ? 84 SER D OG 1 ATOM 5594 N N . LEU D 2 85 ? -8.537 17.313 20.828 1.00 38.20 ? 85 LEU D N 1 ATOM 5595 C CA . LEU D 2 85 ? -8.773 16.018 21.445 1.00 41.21 ? 85 LEU D CA 1 ATOM 5596 C C . LEU D 2 85 ? -9.922 16.069 22.438 1.00 33.87 ? 85 LEU D C 1 ATOM 5597 O O . LEU D 2 85 ? -10.006 16.968 23.274 1.00 33.61 ? 85 LEU D O 1 ATOM 5598 C CB . LEU D 2 85 ? -7.504 15.487 22.114 1.00 38.12 ? 85 LEU D CB 1 ATOM 5599 C CG . LEU D 2 85 ? -6.696 14.516 21.252 1.00 35.99 ? 85 LEU D CG 1 ATOM 5600 C CD1 . LEU D 2 85 ? -6.091 15.214 20.053 1.00 32.34 ? 85 LEU D CD1 1 ATOM 5601 C CD2 . LEU D 2 85 ? -5.620 13.849 22.076 1.00 35.91 ? 85 LEU D CD2 1 ATOM 5602 N N . GLN D 2 86 ? -10.819 15.099 22.332 1.00 31.95 ? 86 GLN D N 1 ATOM 5603 C CA . GLN D 2 86 ? -11.883 14.975 23.311 1.00 37.16 ? 86 GLN D CA 1 ATOM 5604 C C . GLN D 2 86 ? -11.527 13.832 24.241 1.00 35.20 ? 86 GLN D C 1 ATOM 5605 O O . GLN D 2 86 ? -10.589 13.080 23.991 1.00 35.20 ? 86 GLN D O 1 ATOM 5606 C CB . GLN D 2 86 ? -13.241 14.728 22.640 1.00 34.88 ? 86 GLN D CB 1 ATOM 5607 C CG . GLN D 2 86 ? -13.584 15.701 21.499 1.00 43.68 ? 86 GLN D CG 1 ATOM 5608 C CD . GLN D 2 86 ? -13.377 17.165 21.876 1.00 50.10 ? 86 GLN D CD 1 ATOM 5609 O OE1 . GLN D 2 86 ? -13.678 17.591 22.995 1.00 45.13 ? 86 GLN D OE1 1 ATOM 5610 N NE2 . GLN D 2 86 ? -12.838 17.936 20.941 1.00 53.30 ? 86 GLN D NE2 1 ATOM 5611 N N . SER D 2 87 ? -12.283 13.716 25.316 1.00 35.70 ? 87 SER D N 1 ATOM 5612 C CA . SER D 2 87 ? -12.095 12.662 26.284 1.00 31.64 ? 87 SER D CA 1 ATOM 5613 C C . SER D 2 87 ? -11.910 11.287 25.641 1.00 29.81 ? 87 SER D C 1 ATOM 5614 O O . SER D 2 87 ? -11.006 10.549 26.012 1.00 31.66 ? 87 SER D O 1 ATOM 5615 C CB . SER D 2 87 ? -13.277 12.643 27.249 1.00 23.74 ? 87 SER D CB 1 ATOM 5616 O OG . SER D 2 87 ? -13.014 11.773 28.333 1.00 46.74 ? 87 SER D OG 1 ATOM 5617 N N . ASN D 2 88 ? -12.730 10.951 24.654 1.00 27.85 ? 88 ASN D N 1 ATOM 5618 C CA . ASN D 2 88 ? -12.616 9.622 24.050 1.00 34.11 ? 88 ASN D CA 1 ATOM 5619 C C . ASN D 2 88 ? -11.453 9.442 23.071 1.00 36.55 ? 88 ASN D C 1 ATOM 5620 O O . ASN D 2 88 ? -11.388 8.440 22.369 1.00 33.91 ? 88 ASN D O 1 ATOM 5621 C CB . ASN D 2 88 ? -13.935 9.154 23.411 1.00 22.71 ? 88 ASN D CB 1 ATOM 5622 C CG . ASN D 2 88 ? -14.350 9.994 22.221 1.00 39.68 ? 88 ASN D CG 1 ATOM 5623 O OD1 . ASN D 2 88 ? -13.574 10.797 21.690 1.00 44.51 ? 88 ASN D OD1 1 ATOM 5624 N ND2 . ASN D 2 88 ? -15.592 9.813 21.800 1.00 45.62 ? 88 ASN D ND2 1 ATOM 5625 N N . ASP D 2 89 ? -10.550 10.413 23.009 1.00 31.73 ? 89 ASP D N 1 ATOM 5626 C CA . ASP D 2 89 ? -9.352 10.260 22.194 1.00 30.60 ? 89 ASP D CA 1 ATOM 5627 C C . ASP D 2 89 ? -8.226 9.706 23.071 1.00 30.54 ? 89 ASP D C 1 ATOM 5628 O O . ASP D 2 89 ? -7.094 9.496 22.612 1.00 19.12 ? 89 ASP D O 1 ATOM 5629 C CB . ASP D 2 89 ? -8.965 11.580 21.513 1.00 33.87 ? 89 ASP D CB 1 ATOM 5630 C CG . ASP D 2 89 ? -9.885 11.926 20.352 1.00 32.34 ? 89 ASP D CG 1 ATOM 5631 O OD1 . ASP D 2 89 ? -10.220 11.013 19.573 1.00 33.15 ? 89 ASP D OD1 1 ATOM 5632 O OD2 . ASP D 2 89 ? -10.288 13.103 20.219 1.00 35.46 ? 89 ASP D OD2 1 ATOM 5633 N N . THR D 2 90 ? -8.568 9.472 24.338 1.00 25.20 ? 90 THR D N 1 ATOM 5634 C CA . THR D 2 90 ? -7.716 8.754 25.273 1.00 21.44 ? 90 THR D CA 1 ATOM 5635 C C . THR D 2 90 ? -7.500 7.363 24.716 1.00 17.81 ? 90 THR D C 1 ATOM 5636 O O . THR D 2 90 ? -8.461 6.632 24.494 1.00 20.63 ? 90 THR D O 1 ATOM 5637 C CB . THR D 2 90 ? -8.391 8.671 26.675 1.00 21.40 ? 90 THR D CB 1 ATOM 5638 O OG1 . THR D 2 90 ? -8.380 9.966 27.281 1.00 34.07 ? 90 THR D OG1 1 ATOM 5639 C CG2 . THR D 2 90 ? -7.661 7.715 27.592 1.00 14.81 ? 90 THR D CG2 1 ATOM 5640 N N . ALA D 2 91 ? -6.241 7.009 24.477 1.00 19.56 ? 91 ALA D N 1 ATOM 5641 C CA . ALA D 2 91 ? -5.904 5.752 23.823 1.00 22.84 ? 91 ALA D CA 1 ATOM 5642 C C . ALA D 2 91 ? -4.407 5.517 23.836 1.00 20.97 ? 91 ALA D C 1 ATOM 5643 O O . ALA D 2 91 ? -3.638 6.404 24.204 1.00 21.19 ? 91 ALA D O 1 ATOM 5644 C CB . ALA D 2 91 ? -6.426 5.756 22.360 1.00 19.51 ? 91 ALA D CB 1 ATOM 5645 N N . ILE D 2 92 ? -3.991 4.318 23.436 1.00 15.39 ? 92 ILE D N 1 ATOM 5646 C CA . ILE D 2 92 ? -2.581 4.088 23.173 1.00 19.64 ? 92 ILE D CA 1 ATOM 5647 C C . ILE D 2 92 ? -2.342 4.273 21.675 1.00 28.19 ? 92 ILE D C 1 ATOM 5648 O O . ILE D 2 92 ? -2.970 3.585 20.857 1.00 23.18 ? 92 ILE D O 1 ATOM 5649 C CB . ILE D 2 92 ? -2.107 2.698 23.620 1.00 18.01 ? 92 ILE D CB 1 ATOM 5650 C CG1 . ILE D 2 92 ? -2.344 2.510 25.122 1.00 32.14 ? 92 ILE D CG1 1 ATOM 5651 C CG2 . ILE D 2 92 ? -0.637 2.520 23.301 1.00 15.22 ? 92 ILE D CG2 1 ATOM 5652 C CD1 . ILE D 2 92 ? -2.102 1.091 25.621 1.00 30.01 ? 92 ILE D CD1 1 ATOM 5653 N N . TYR D 2 93 ? -1.443 5.205 21.332 1.00 22.56 ? 93 TYR D N 1 ATOM 5654 C CA . TYR D 2 93 ? -1.105 5.513 19.938 1.00 20.24 ? 93 TYR D CA 1 ATOM 5655 C C . TYR D 2 93 ? 0.180 4.833 19.511 1.00 17.35 ? 93 TYR D C 1 ATOM 5656 O O . TYR D 2 93 ? 1.193 4.972 20.180 1.00 21.06 ? 93 TYR D O 1 ATOM 5657 C CB . TYR D 2 93 ? -1.005 7.031 19.741 1.00 15.66 ? 93 TYR D CB 1 ATOM 5658 C CG . TYR D 2 93 ? -2.354 7.710 19.852 1.00 20.82 ? 93 TYR D CG 1 ATOM 5659 C CD1 . TYR D 2 93 ? -2.931 7.964 21.092 1.00 24.30 ? 93 TYR D CD1 1 ATOM 5660 C CD2 . TYR D 2 93 ? -3.070 8.056 18.717 1.00 20.10 ? 93 TYR D CD2 1 ATOM 5661 C CE1 . TYR D 2 93 ? -4.167 8.562 21.190 1.00 20.68 ? 93 TYR D CE1 1 ATOM 5662 C CE2 . TYR D 2 93 ? -4.299 8.645 18.807 1.00 17.18 ? 93 TYR D CE2 1 ATOM 5663 C CZ . TYR D 2 93 ? -4.847 8.895 20.040 1.00 21.58 ? 93 TYR D CZ 1 ATOM 5664 O OH . TYR D 2 93 ? -6.082 9.487 20.108 1.00 23.55 ? 93 TYR D OH 1 ATOM 5665 N N . TYR D 2 94 ? 0.130 4.087 18.412 1.00 16.73 ? 94 TYR D N 1 ATOM 5666 C CA . TYR D 2 94 ? 1.309 3.378 17.899 1.00 22.35 ? 94 TYR D CA 1 ATOM 5667 C C . TYR D 2 94 ? 1.726 3.914 16.539 1.00 23.70 ? 94 TYR D C 1 ATOM 5668 O O . TYR D 2 94 ? 0.883 4.284 15.714 1.00 20.73 ? 94 TYR D O 1 ATOM 5669 C CB . TYR D 2 94 ? 1.048 1.869 17.709 1.00 16.82 ? 94 TYR D CB 1 ATOM 5670 C CG . TYR D 2 94 ? 0.599 1.110 18.933 1.00 18.68 ? 94 TYR D CG 1 ATOM 5671 C CD1 . TYR D 2 94 ? 1.514 0.436 19.729 1.00 20.53 ? 94 TYR D CD1 1 ATOM 5672 C CD2 . TYR D 2 94 ? -0.739 1.050 19.283 1.00 19.77 ? 94 TYR D CD2 1 ATOM 5673 C CE1 . TYR D 2 94 ? 1.114 -0.266 20.844 1.00 17.71 ? 94 TYR D CE1 1 ATOM 5674 C CE2 . TYR D 2 94 ? -1.147 0.348 20.396 1.00 24.52 ? 94 TYR D CE2 1 ATOM 5675 C CZ . TYR D 2 94 ? -0.215 -0.307 21.174 1.00 21.04 ? 94 TYR D CZ 1 ATOM 5676 O OH . TYR D 2 94 ? -0.621 -1.000 22.289 1.00 25.21 ? 94 TYR D OH 1 ATOM 5677 N N . CYS D 2 95 ? 3.027 3.930 16.292 1.00 18.69 ? 95 CYS D N 1 ATOM 5678 C CA . CYS D 2 95 ? 3.504 4.021 14.927 1.00 23.80 ? 95 CYS D CA 1 ATOM 5679 C C . CYS D 2 95 ? 3.896 2.605 14.496 1.00 24.25 ? 95 CYS D C 1 ATOM 5680 O O . CYS D 2 95 ? 4.280 1.786 15.335 1.00 20.98 ? 95 CYS D O 1 ATOM 5681 C CB . CYS D 2 95 ? 4.656 5.030 14.783 1.00 18.84 ? 95 CYS D CB 1 ATOM 5682 S SG . CYS D 2 95 ? 6.239 4.623 15.577 1.00 27.71 ? 95 CYS D SG 1 ATOM 5683 N N . ALA D 2 96 ? 3.777 2.314 13.205 1.00 19.45 ? 96 ALA D N 1 ATOM 5684 C CA . ALA D 2 96 ? 4.036 0.969 12.708 1.00 21.90 ? 96 ALA D CA 1 ATOM 5685 C C . ALA D 2 96 ? 4.624 0.943 11.281 1.00 21.23 ? 96 ALA D C 1 ATOM 5686 O O . ALA D 2 96 ? 4.395 1.855 10.479 1.00 22.53 ? 96 ALA D O 1 ATOM 5687 C CB . ALA D 2 96 ? 2.758 0.139 12.783 1.00 18.16 ? 96 ALA D CB 1 ATOM 5688 N N . ARG D 2 97 ? 5.395 -0.100 10.978 1.00 24.65 ? 97 ARG D N 1 ATOM 5689 C CA . ARG D 2 97 ? 5.952 -0.297 9.640 1.00 19.83 ? 97 ARG D CA 1 ATOM 5690 C C . ARG D 2 97 ? 5.482 -1.627 9.072 1.00 18.82 ? 97 ARG D C 1 ATOM 5691 O O . ARG D 2 97 ? 5.452 -2.632 9.781 1.00 23.72 ? 97 ARG D O 1 ATOM 5692 C CB . ARG D 2 97 ? 7.483 -0.277 9.660 1.00 21.28 ? 97 ARG D CB 1 ATOM 5693 C CG . ARG D 2 97 ? 8.115 0.279 8.367 1.00 24.78 ? 97 ARG D CG 1 ATOM 5694 C CD . ARG D 2 97 ? 9.459 -0.362 8.062 1.00 17.83 ? 97 ARG D CD 1 ATOM 5695 N NE . ARG D 2 97 ? 9.263 -1.725 7.604 1.00 23.73 ? 97 ARG D NE 1 ATOM 5696 C CZ . ARG D 2 97 ? 10.225 -2.532 7.173 1.00 21.76 ? 97 ARG D CZ 1 ATOM 5697 N NH1 . ARG D 2 97 ? 11.479 -2.122 7.143 1.00 23.33 ? 97 ARG D NH1 1 ATOM 5698 N NH2 . ARG D 2 97 ? 9.927 -3.755 6.763 1.00 19.48 ? 97 ARG D NH2 1 ATOM 5699 N N . ALA D 2 98 ? 5.113 -1.628 7.795 1.00 17.69 ? 98 ALA D N 1 ATOM 5700 C CA . ALA D 2 98 ? 4.716 -2.852 7.114 1.00 19.28 ? 98 ALA D CA 1 ATOM 5701 C C . ALA D 2 98 ? 5.951 -3.653 6.695 1.00 20.69 ? 98 ALA D C 1 ATOM 5702 O O . ALA D 2 98 ? 7.058 -3.130 6.690 1.00 20.27 ? 98 ALA D O 1 ATOM 5703 C CB . ALA D 2 98 ? 3.838 -2.530 5.916 1.00 19.98 ? 98 ALA D CB 1 ATOM 5704 N N . LEU D 2 99 ? 5.762 -4.926 6.356 1.00 24.91 ? 99 LEU D N 1 ATOM 5705 C CA . LEU D 2 99 ? 6.848 -5.752 5.825 1.00 27.05 ? 99 LEU D CA 1 ATOM 5706 C C . LEU D 2 99 ? 7.338 -5.176 4.506 1.00 30.31 ? 99 LEU D C 1 ATOM 5707 O O . LEU D 2 99 ? 8.493 -5.344 4.107 1.00 30.34 ? 99 LEU D O 1 ATOM 5708 C CB . LEU D 2 99 ? 6.332 -7.156 5.540 1.00 30.59 ? 99 LEU D CB 1 ATOM 5709 C CG . LEU D 2 99 ? 6.642 -8.271 6.528 1.00 33.34 ? 99 LEU D CG 1 ATOM 5710 C CD1 . LEU D 2 99 ? 5.957 -9.541 6.050 1.00 27.88 ? 99 LEU D CD1 1 ATOM 5711 C CD2 . LEU D 2 99 ? 8.138 -8.479 6.643 1.00 29.40 ? 99 LEU D CD2 1 ATOM 5712 N N . THR D 2 100 ? 6.426 -4.482 3.840 1.00 34.02 ? 100 THR D N 1 ATOM 5713 C CA . THR D 2 100 ? 6.588 -4.096 2.454 1.00 32.82 ? 100 THR D CA 1 ATOM 5714 C C . THR D 2 100 ? 6.320 -2.603 2.284 1.00 32.36 ? 100 THR D C 1 ATOM 5715 O O . THR D 2 100 ? 5.452 -2.048 2.964 1.00 33.20 ? 100 THR D O 1 ATOM 5716 C CB . THR D 2 100 ? 5.583 -4.859 1.607 1.00 35.85 ? 100 THR D CB 1 ATOM 5717 O OG1 . THR D 2 100 ? 5.855 -6.264 1.682 1.00 41.20 ? 100 THR D OG1 1 ATOM 5718 C CG2 . THR D 2 100 ? 5.716 -4.444 0.241 1.00 33.25 ? 100 THR D CG2 1 ATOM 5719 N N . TYR D 2 101 ? 7.056 -1.948 1.388 1.00 25.06 ? 101 TYR D N 1 ATOM 5720 C CA . TYR D 2 101 ? 6.926 -0.505 1.240 1.00 27.89 ? 101 TYR D CA 1 ATOM 5721 C C . TYR D 2 101 ? 5.494 -0.036 0.971 1.00 26.72 ? 101 TYR D C 1 ATOM 5722 O O . TYR D 2 101 ? 5.103 1.038 1.420 1.00 28.24 ? 101 TYR D O 1 ATOM 5723 C CB . TYR D 2 101 ? 7.901 0.050 0.183 1.00 22.59 ? 101 TYR D CB 1 ATOM 5724 C CG . TYR D 2 101 ? 7.509 -0.166 -1.258 1.00 25.78 ? 101 TYR D CG 1 ATOM 5725 C CD1 . TYR D 2 101 ? 6.595 0.671 -1.893 1.00 24.51 ? 101 TYR D CD1 1 ATOM 5726 C CD2 . TYR D 2 101 ? 8.087 -1.190 -2.003 1.00 27.48 ? 101 TYR D CD2 1 ATOM 5727 C CE1 . TYR D 2 101 ? 6.249 0.468 -3.228 1.00 32.74 ? 101 TYR D CE1 1 ATOM 5728 C CE2 . TYR D 2 101 ? 7.751 -1.396 -3.332 1.00 20.86 ? 101 TYR D CE2 1 ATOM 5729 C CZ . TYR D 2 101 ? 6.833 -0.574 -3.943 1.00 28.61 ? 101 TYR D CZ 1 ATOM 5730 O OH . TYR D 2 101 ? 6.505 -0.789 -5.271 1.00 25.21 ? 101 TYR D OH 1 ATOM 5731 N N . TYR D 2 102 ? 4.721 -0.846 0.253 1.00 26.63 ? 102 TYR D N 1 ATOM 5732 C CA . TYR D 2 102 ? 3.386 -0.452 -0.202 1.00 25.72 ? 102 TYR D CA 1 ATOM 5733 C C . TYR D 2 102 ? 2.247 -1.081 0.619 1.00 21.51 ? 102 TYR D C 1 ATOM 5734 O O . TYR D 2 102 ? 1.076 -0.713 0.467 1.00 20.31 ? 102 TYR D O 1 ATOM 5735 C CB . TYR D 2 102 ? 3.212 -0.814 -1.687 1.00 19.09 ? 102 TYR D CB 1 ATOM 5736 C CG . TYR D 2 102 ? 3.405 -2.289 -1.962 1.00 17.56 ? 102 TYR D CG 1 ATOM 5737 C CD1 . TYR D 2 102 ? 2.398 -3.201 -1.688 1.00 17.02 ? 102 TYR D CD1 1 ATOM 5738 C CD2 . TYR D 2 102 ? 4.603 -2.770 -2.471 1.00 20.68 ? 102 TYR D CD2 1 ATOM 5739 C CE1 . TYR D 2 102 ? 2.568 -4.545 -1.913 1.00 18.95 ? 102 TYR D CE1 1 ATOM 5740 C CE2 . TYR D 2 102 ? 4.779 -4.124 -2.714 1.00 25.80 ? 102 TYR D CE2 1 ATOM 5741 C CZ . TYR D 2 102 ? 3.754 -5.008 -2.428 1.00 24.66 ? 102 TYR D CZ 1 ATOM 5742 O OH . TYR D 2 102 ? 3.917 -6.361 -2.655 1.00 21.47 ? 102 TYR D OH 1 ATOM 5743 N N . ASP D 2 103 ? 2.583 -2.041 1.467 1.00 16.09 ? 103 ASP D N 1 ATOM 5744 C CA . ASP D 2 103 ? 1.552 -2.872 2.092 1.00 25.02 ? 103 ASP D CA 1 ATOM 5745 C C . ASP D 2 103 ? 1.106 -2.412 3.487 1.00 25.49 ? 103 ASP D C 1 ATOM 5746 O O . ASP D 2 103 ? 1.565 -1.398 4.004 1.00 29.72 ? 103 ASP D O 1 ATOM 5747 C CB . ASP D 2 103 ? 1.992 -4.341 2.128 1.00 26.21 ? 103 ASP D CB 1 ATOM 5748 C CG . ASP D 2 103 ? 0.826 -5.302 1.936 1.00 34.05 ? 103 ASP D CG 1 ATOM 5749 O OD1 . ASP D 2 103 ? -0.334 -4.878 2.161 1.00 34.41 ? 103 ASP D OD1 1 ATOM 5750 O OD2 . ASP D 2 103 ? 1.059 -6.476 1.564 1.00 26.31 ? 103 ASP D OD2 1 ATOM 5751 N N . TYR D 2 104 ? 0.205 -3.175 4.090 1.00 25.26 ? 104 TYR D N 1 ATOM 5752 C CA . TYR D 2 104 ? -0.383 -2.793 5.361 1.00 24.33 ? 104 TYR D CA 1 ATOM 5753 C C . TYR D 2 104 ? -0.242 -3.869 6.440 1.00 24.46 ? 104 TYR D C 1 ATOM 5754 O O . TYR D 2 104 ? -0.933 -3.824 7.453 1.00 25.38 ? 104 TYR D O 1 ATOM 5755 C CB . TYR D 2 104 ? -1.860 -2.451 5.172 1.00 19.56 ? 104 TYR D CB 1 ATOM 5756 C CG . TYR D 2 104 ? -2.133 -1.185 4.400 1.00 23.11 ? 104 TYR D CG 1 ATOM 5757 C CD1 . TYR D 2 104 ? -1.928 -1.128 3.023 1.00 24.18 ? 104 TYR D CD1 1 ATOM 5758 C CD2 . TYR D 2 104 ? -2.636 -0.054 5.035 1.00 20.92 ? 104 TYR D CD2 1 ATOM 5759 C CE1 . TYR D 2 104 ? -2.192 0.020 2.308 1.00 22.43 ? 104 TYR D CE1 1 ATOM 5760 C CE2 . TYR D 2 104 ? -2.906 1.109 4.321 1.00 24.85 ? 104 TYR D CE2 1 ATOM 5761 C CZ . TYR D 2 104 ? -2.678 1.136 2.953 1.00 29.05 ? 104 TYR D CZ 1 ATOM 5762 O OH . TYR D 2 104 ? -2.931 2.272 2.221 1.00 28.94 ? 104 TYR D OH 1 ATOM 5763 N N . GLU D 2 105 ? 0.621 -4.852 6.218 1.00 23.72 ? 105 GLU D N 1 ATOM 5764 C CA . GLU D 2 105 ? 0.787 -5.900 7.218 1.00 23.46 ? 105 GLU D CA 1 ATOM 5765 C C . GLU D 2 105 ? 1.895 -5.501 8.193 1.00 27.67 ? 105 GLU D C 1 ATOM 5766 O O . GLU D 2 105 ? 3.077 -5.464 7.842 1.00 27.74 ? 105 GLU D O 1 ATOM 5767 C CB . GLU D 2 105 ? 0.971 -7.296 6.594 1.00 21.55 ? 105 GLU D CB 1 ATOM 5768 C CG . GLU D 2 105 ? 2.349 -7.643 6.063 1.00 37.45 ? 105 GLU D CG 1 ATOM 5769 C CD . GLU D 2 105 ? 2.695 -6.965 4.748 1.00 34.55 ? 105 GLU D CD 1 ATOM 5770 O OE1 . GLU D 2 105 ? 2.749 -7.680 3.727 1.00 36.48 ? 105 GLU D OE1 1 ATOM 5771 O OE2 . GLU D 2 105 ? 2.941 -5.735 4.736 1.00 31.68 ? 105 GLU D OE2 1 ATOM 5772 N N . PHE D 2 106 ? 1.483 -5.163 9.412 1.00 21.08 ? 106 PHE D N 1 ATOM 5773 C CA . PHE D 2 106 ? 2.336 -4.442 10.345 1.00 22.87 ? 106 PHE D CA 1 ATOM 5774 C C . PHE D 2 106 ? 3.244 -5.368 11.141 1.00 22.53 ? 106 PHE D C 1 ATOM 5775 O O . PHE D 2 106 ? 2.865 -5.882 12.186 1.00 21.43 ? 106 PHE D O 1 ATOM 5776 C CB . PHE D 2 106 ? 1.490 -3.560 11.265 1.00 17.48 ? 106 PHE D CB 1 ATOM 5777 C CG . PHE D 2 106 ? 0.599 -2.601 10.518 1.00 17.51 ? 106 PHE D CG 1 ATOM 5778 C CD1 . PHE D 2 106 ? -0.773 -2.661 10.646 1.00 16.78 ? 106 PHE D CD1 1 ATOM 5779 C CD2 . PHE D 2 106 ? 1.142 -1.638 9.677 1.00 25.32 ? 106 PHE D CD2 1 ATOM 5780 C CE1 . PHE D 2 106 ? -1.590 -1.769 9.961 1.00 21.17 ? 106 PHE D CE1 1 ATOM 5781 C CE2 . PHE D 2 106 ? 0.326 -0.736 8.981 1.00 23.83 ? 106 PHE D CE2 1 ATOM 5782 C CZ . PHE D 2 106 ? -1.037 -0.808 9.122 1.00 22.00 ? 106 PHE D CZ 1 ATOM 5783 N N . ALA D 2 107 ? 4.454 -5.558 10.630 1.00 20.52 ? 107 ALA D N 1 ATOM 5784 C CA . ALA D 2 107 ? 5.420 -6.435 11.260 1.00 19.68 ? 107 ALA D CA 1 ATOM 5785 C C . ALA D 2 107 ? 6.235 -5.729 12.357 1.00 23.96 ? 107 ALA D C 1 ATOM 5786 O O . ALA D 2 107 ? 6.739 -6.376 13.266 1.00 26.80 ? 107 ALA D O 1 ATOM 5787 C CB . ALA D 2 107 ? 6.329 -7.037 10.203 1.00 16.23 ? 107 ALA D CB 1 ATOM 5788 N N . TYR D 2 108 ? 6.360 -4.408 12.271 1.00 22.99 ? 108 TYR D N 1 ATOM 5789 C CA . TYR D 2 108 ? 7.167 -3.645 13.232 1.00 22.64 ? 108 TYR D CA 1 ATOM 5790 C C . TYR D 2 108 ? 6.371 -2.527 13.895 1.00 21.08 ? 108 TYR D C 1 ATOM 5791 O O . TYR D 2 108 ? 5.771 -1.692 13.214 1.00 21.37 ? 108 TYR D O 1 ATOM 5792 C CB . TYR D 2 108 ? 8.459 -3.114 12.571 1.00 26.21 ? 108 TYR D CB 1 ATOM 5793 C CG . TYR D 2 108 ? 9.263 -4.210 11.888 1.00 31.45 ? 108 TYR D CG 1 ATOM 5794 C CD1 . TYR D 2 108 ? 9.135 -4.449 10.511 1.00 29.71 ? 108 TYR D CD1 1 ATOM 5795 C CD2 . TYR D 2 108 ? 10.116 -5.034 12.622 1.00 23.83 ? 108 TYR D CD2 1 ATOM 5796 C CE1 . TYR D 2 108 ? 9.857 -5.461 9.885 1.00 24.17 ? 108 TYR D CE1 1 ATOM 5797 C CE2 . TYR D 2 108 ? 10.829 -6.047 12.016 1.00 24.22 ? 108 TYR D CE2 1 ATOM 5798 C CZ . TYR D 2 108 ? 10.699 -6.259 10.645 1.00 37.69 ? 108 TYR D CZ 1 ATOM 5799 O OH . TYR D 2 108 ? 11.414 -7.273 10.043 1.00 42.42 ? 108 TYR D OH 1 ATOM 5800 N N . TRP D 2 109 ? 6.350 -2.524 15.229 1.00 30.50 ? 109 TRP D N 1 ATOM 5801 C CA . TRP D 2 109 ? 5.575 -1.522 15.978 1.00 24.50 ? 109 TRP D CA 1 ATOM 5802 C C . TRP D 2 109 ? 6.437 -0.691 16.898 1.00 17.17 ? 109 TRP D C 1 ATOM 5803 O O . TRP D 2 109 ? 7.512 -1.128 17.307 1.00 26.51 ? 109 TRP D O 1 ATOM 5804 C CB . TRP D 2 109 ? 4.487 -2.189 16.809 1.00 19.28 ? 109 TRP D CB 1 ATOM 5805 C CG . TRP D 2 109 ? 3.458 -2.899 15.988 1.00 16.19 ? 109 TRP D CG 1 ATOM 5806 C CD1 . TRP D 2 109 ? 3.644 -4.015 15.227 1.00 17.48 ? 109 TRP D CD1 1 ATOM 5807 C CD2 . TRP D 2 109 ? 2.072 -2.553 15.866 1.00 15.42 ? 109 TRP D CD2 1 ATOM 5808 N NE1 . TRP D 2 109 ? 2.461 -4.387 14.645 1.00 18.95 ? 109 TRP D NE1 1 ATOM 5809 C CE2 . TRP D 2 109 ? 1.480 -3.504 15.021 1.00 20.32 ? 109 TRP D CE2 1 ATOM 5810 C CE3 . TRP D 2 109 ? 1.275 -1.538 16.401 1.00 20.89 ? 109 TRP D CE3 1 ATOM 5811 C CZ2 . TRP D 2 109 ? 0.129 -3.461 14.679 1.00 23.32 ? 109 TRP D CZ2 1 ATOM 5812 C CZ3 . TRP D 2 109 ? -0.071 -1.493 16.062 1.00 21.34 ? 109 TRP D CZ3 1 ATOM 5813 C CH2 . TRP D 2 109 ? -0.628 -2.449 15.208 1.00 24.25 ? 109 TRP D CH2 1 ATOM 5814 N N . GLY D 2 110 ? 5.962 0.510 17.215 1.00 20.29 ? 110 GLY D N 1 ATOM 5815 C CA . GLY D 2 110 ? 6.550 1.316 18.270 1.00 19.29 ? 110 GLY D CA 1 ATOM 5816 C C . GLY D 2 110 ? 6.076 0.766 19.603 1.00 22.10 ? 110 GLY D C 1 ATOM 5817 O O . GLY D 2 110 ? 5.228 -0.139 19.630 1.00 21.25 ? 110 GLY D O 1 ATOM 5818 N N . GLN D 2 111 ? 6.593 1.294 20.708 1.00 17.69 ? 111 GLN D N 1 ATOM 5819 C CA . GLN D 2 111 ? 6.189 0.775 22.017 1.00 18.29 ? 111 GLN D CA 1 ATOM 5820 C C . GLN D 2 111 ? 4.830 1.315 22.438 1.00 19.36 ? 111 GLN D C 1 ATOM 5821 O O . GLN D 2 111 ? 4.223 0.825 23.395 1.00 17.96 ? 111 GLN D O 1 ATOM 5822 C CB . GLN D 2 111 ? 7.245 1.036 23.101 1.00 8.78 ? 111 GLN D CB 1 ATOM 5823 C CG . GLN D 2 111 ? 7.250 2.428 23.658 1.00 14.49 ? 111 GLN D CG 1 ATOM 5824 C CD . GLN D 2 111 ? 8.151 3.388 22.899 1.00 21.96 ? 111 GLN D CD 1 ATOM 5825 O OE1 . GLN D 2 111 ? 8.615 3.113 21.778 1.00 26.17 ? 111 GLN D OE1 1 ATOM 5826 N NE2 . GLN D 2 111 ? 8.406 4.532 23.515 1.00 21.55 ? 111 GLN D NE2 1 ATOM 5827 N N . GLY D 2 112 ? 4.349 2.315 21.703 1.00 22.48 ? 112 GLY D N 1 ATOM 5828 C CA . GLY D 2 112 ? 3.058 2.917 21.979 1.00 23.59 ? 112 GLY D CA 1 ATOM 5829 C C . GLY D 2 112 ? 3.174 4.058 22.974 1.00 25.52 ? 112 GLY D C 1 ATOM 5830 O O . GLY D 2 112 ? 4.017 4.038 23.867 1.00 27.46 ? 112 GLY D O 1 ATOM 5831 N N . THR D 2 113 ? 2.333 5.069 22.805 1.00 25.21 ? 113 THR D N 1 ATOM 5832 C CA . THR D 2 113 ? 2.330 6.219 23.693 1.00 20.43 ? 113 THR D CA 1 ATOM 5833 C C . THR D 2 113 ? 0.951 6.351 24.293 1.00 19.29 ? 113 THR D C 1 ATOM 5834 O O . THR D 2 113 ? 0.000 6.674 23.566 1.00 21.99 ? 113 THR D O 1 ATOM 5835 C CB . THR D 2 113 ? 2.642 7.508 22.923 1.00 22.89 ? 113 THR D CB 1 ATOM 5836 O OG1 . THR D 2 113 ? 3.936 7.398 22.313 1.00 29.89 ? 113 THR D OG1 1 ATOM 5837 C CG2 . THR D 2 113 ? 2.613 8.712 23.853 1.00 18.98 ? 113 THR D CG2 1 ATOM 5838 N N . LEU D 2 114 ? 0.831 6.087 25.600 1.00 18.46 ? 114 LEU D N 1 ATOM 5839 C CA . LEU D 2 114 ? -0.460 6.220 26.293 1.00 16.32 ? 114 LEU D CA 1 ATOM 5840 C C . LEU D 2 114 ? -0.778 7.689 26.481 1.00 19.62 ? 114 LEU D C 1 ATOM 5841 O O . LEU D 2 114 ? -0.041 8.426 27.143 1.00 23.72 ? 114 LEU D O 1 ATOM 5842 C CB . LEU D 2 114 ? -0.492 5.464 27.638 1.00 13.22 ? 114 LEU D CB 1 ATOM 5843 C CG . LEU D 2 114 ? -1.682 5.649 28.600 1.00 21.08 ? 114 LEU D CG 1 ATOM 5844 C CD1 . LEU D 2 114 ? -3.024 5.563 27.892 1.00 20.23 ? 114 LEU D CD1 1 ATOM 5845 C CD2 . LEU D 2 114 ? -1.646 4.641 29.750 1.00 20.67 ? 114 LEU D CD2 1 ATOM 5846 N N . VAL D 2 115 ? -1.877 8.112 25.878 1.00 22.86 ? 115 VAL D N 1 ATOM 5847 C CA . VAL D 2 115 ? -2.256 9.518 25.860 1.00 21.54 ? 115 VAL D CA 1 ATOM 5848 C C . VAL D 2 115 ? -3.577 9.694 26.602 1.00 25.76 ? 115 VAL D C 1 ATOM 5849 O O . VAL D 2 115 ? -4.590 9.090 26.236 1.00 25.94 ? 115 VAL D O 1 ATOM 5850 C CB . VAL D 2 115 ? -2.398 10.010 24.403 1.00 20.50 ? 115 VAL D CB 1 ATOM 5851 C CG1 . VAL D 2 115 ? -2.788 11.483 24.347 1.00 26.28 ? 115 VAL D CG1 1 ATOM 5852 C CG2 . VAL D 2 115 ? -1.104 9.757 23.634 1.00 16.64 ? 115 VAL D CG2 1 ATOM 5853 N N . THR D 2 116 ? -3.558 10.508 27.653 1.00 22.55 ? 116 THR D N 1 ATOM 5854 C CA . THR D 2 116 ? -4.752 10.744 28.450 1.00 25.45 ? 116 THR D CA 1 ATOM 5855 C C . THR D 2 116 ? -5.286 12.130 28.154 1.00 30.04 ? 116 THR D C 1 ATOM 5856 O O . THR D 2 116 ? -4.520 13.094 28.089 1.00 27.80 ? 116 THR D O 1 ATOM 5857 C CB . THR D 2 116 ? -4.466 10.598 29.963 1.00 25.31 ? 116 THR D CB 1 ATOM 5858 O OG1 . THR D 2 116 ? -3.957 9.287 30.227 1.00 18.90 ? 116 THR D OG1 1 ATOM 5859 C CG2 . THR D 2 116 ? -5.741 10.811 30.795 1.00 24.28 ? 116 THR D CG2 1 ATOM 5860 N N . VAL D 2 117 ? -6.596 12.218 27.936 1.00 28.77 ? 117 VAL D N 1 ATOM 5861 C CA . VAL D 2 117 ? -7.249 13.509 27.771 1.00 22.95 ? 117 VAL D CA 1 ATOM 5862 C C . VAL D 2 117 ? -8.050 13.825 29.024 1.00 30.35 ? 117 VAL D C 1 ATOM 5863 O O . VAL D 2 117 ? -9.017 13.135 29.353 1.00 28.87 ? 117 VAL D O 1 ATOM 5864 C CB . VAL D 2 117 ? -8.159 13.552 26.539 1.00 27.55 ? 117 VAL D CB 1 ATOM 5865 C CG1 . VAL D 2 117 ? -8.754 14.943 26.364 1.00 29.33 ? 117 VAL D CG1 1 ATOM 5866 C CG2 . VAL D 2 117 ? -7.384 13.167 25.313 1.00 27.84 ? 117 VAL D CG2 1 ATOM 5867 N N . SER D 2 118 ? -7.621 14.861 29.735 1.00 31.74 ? 118 SER D N 1 ATOM 5868 C CA . SER D 2 118 ? -8.272 15.255 30.971 1.00 26.59 ? 118 SER D CA 1 ATOM 5869 C C . SER D 2 118 ? -7.926 16.703 31.254 1.00 32.39 ? 118 SER D C 1 ATOM 5870 O O . SER D 2 118 ? -6.879 17.195 30.833 1.00 31.68 ? 118 SER D O 1 ATOM 5871 C CB . SER D 2 118 ? -7.808 14.368 32.136 1.00 31.19 ? 118 SER D CB 1 ATOM 5872 O OG . SER D 2 118 ? -8.731 14.373 33.215 1.00 35.29 ? 118 SER D OG 1 ATOM 5873 N N . ALA D 2 119 ? -8.824 17.389 31.954 1.00 36.52 ? 119 ALA D N 1 ATOM 5874 C CA . ALA D 2 119 ? -8.566 18.747 32.400 1.00 38.00 ? 119 ALA D CA 1 ATOM 5875 C C . ALA D 2 119 ? -7.677 18.772 33.658 1.00 41.87 ? 119 ALA D C 1 ATOM 5876 O O . ALA D 2 119 ? -7.120 19.811 34.019 1.00 45.48 ? 119 ALA D O 1 ATOM 5877 C CB . ALA D 2 119 ? -9.882 19.471 32.643 1.00 35.30 ? 119 ALA D CB 1 ATOM 5878 N N . ALA D 2 120 ? -7.533 17.618 34.304 1.00 30.12 ? 120 ALA D N 1 ATOM 5879 C CA . ALA D 2 120 ? -6.703 17.473 35.508 1.00 37.66 ? 120 ALA D CA 1 ATOM 5880 C C . ALA D 2 120 ? -5.218 17.863 35.355 1.00 30.45 ? 120 ALA D C 1 ATOM 5881 O O . ALA D 2 120 ? -4.743 18.137 34.255 1.00 32.85 ? 120 ALA D O 1 ATOM 5882 C CB . ALA D 2 120 ? -6.825 16.046 36.052 1.00 34.52 ? 120 ALA D CB 1 ATOM 5883 N N . SER D 2 121 ? -4.490 17.883 36.469 1.00 35.75 ? 121 SER D N 1 ATOM 5884 C CA . SER D 2 121 ? -3.062 18.206 36.446 1.00 30.51 ? 121 SER D CA 1 ATOM 5885 C C . SER D 2 121 ? -2.243 16.939 36.552 1.00 31.62 ? 121 SER D C 1 ATOM 5886 O O . SER D 2 121 ? -2.727 15.914 37.029 1.00 33.71 ? 121 SER D O 1 ATOM 5887 C CB . SER D 2 121 ? -2.665 19.127 37.606 1.00 32.38 ? 121 SER D CB 1 ATOM 5888 O OG . SER D 2 121 ? -3.476 20.282 37.669 1.00 47.10 ? 121 SER D OG 1 ATOM 5889 N N . THR D 2 122 ? -0.997 17.024 36.105 1.00 29.23 ? 122 THR D N 1 ATOM 5890 C CA . THR D 2 122 ? -0.057 15.924 36.219 1.00 31.03 ? 122 THR D CA 1 ATOM 5891 C C . THR D 2 122 ? 0.473 15.891 37.647 1.00 30.21 ? 122 THR D C 1 ATOM 5892 O O . THR D 2 122 ? 0.683 16.942 38.251 1.00 26.41 ? 122 THR D O 1 ATOM 5893 C CB . THR D 2 122 ? 1.085 16.093 35.213 1.00 21.28 ? 122 THR D CB 1 ATOM 5894 O OG1 . THR D 2 122 ? 0.537 16.028 33.895 1.00 32.89 ? 122 THR D OG1 1 ATOM 5895 C CG2 . THR D 2 122 ? 2.088 14.990 35.344 1.00 23.94 ? 122 THR D CG2 1 ATOM 5896 N N . LYS D 2 123 ? 0.656 14.693 38.194 1.00 22.44 ? 123 LYS D N 1 ATOM 5897 C CA . LYS D 2 123 ? 1.141 14.550 39.562 1.00 24.46 ? 123 LYS D CA 1 ATOM 5898 C C . LYS D 2 123 ? 2.022 13.316 39.719 1.00 19.81 ? 123 LYS D C 1 ATOM 5899 O O . LYS D 2 123 ? 1.612 12.209 39.373 1.00 19.95 ? 123 LYS D O 1 ATOM 5900 C CB . LYS D 2 123 ? -0.029 14.501 40.547 1.00 21.26 ? 123 LYS D CB 1 ATOM 5901 C CG . LYS D 2 123 ? 0.399 14.576 41.990 1.00 24.92 ? 123 LYS D CG 1 ATOM 5902 C CD . LYS D 2 123 ? -0.775 14.374 42.959 1.00 32.19 ? 123 LYS D CD 1 ATOM 5903 C CE . LYS D 2 123 ? -0.283 14.318 44.415 1.00 33.68 ? 123 LYS D CE 1 ATOM 5904 N NZ . LYS D 2 123 ? 0.857 13.349 44.621 1.00 28.10 ? 123 LYS D NZ 1 ATOM 5905 N N . GLY D 2 124 ? 3.237 13.514 40.222 1.00 15.95 ? 124 GLY D N 1 ATOM 5906 C CA . GLY D 2 124 ? 4.135 12.403 40.476 1.00 16.68 ? 124 GLY D CA 1 ATOM 5907 C C . GLY D 2 124 ? 3.617 11.579 41.646 1.00 19.04 ? 124 GLY D C 1 ATOM 5908 O O . GLY D 2 124 ? 2.867 12.082 42.474 1.00 16.66 ? 124 GLY D O 1 ATOM 5909 N N . PRO D 2 125 ? 3.999 10.301 41.710 1.00 15.07 ? 125 PRO D N 1 ATOM 5910 C CA . PRO D 2 125 ? 3.493 9.445 42.780 1.00 16.59 ? 125 PRO D CA 1 ATOM 5911 C C . PRO D 2 125 ? 4.367 9.545 44.029 1.00 25.43 ? 125 PRO D C 1 ATOM 5912 O O . PRO D 2 125 ? 5.501 10.028 43.970 1.00 19.11 ? 125 PRO D O 1 ATOM 5913 C CB . PRO D 2 125 ? 3.632 8.043 42.181 1.00 19.36 ? 125 PRO D CB 1 ATOM 5914 C CG . PRO D 2 125 ? 4.839 8.148 41.282 1.00 10.99 ? 125 PRO D CG 1 ATOM 5915 C CD . PRO D 2 125 ? 4.832 9.558 40.742 1.00 13.32 ? 125 PRO D CD 1 ATOM 5916 N N . SER D 2 126 ? 3.825 9.093 45.153 1.00 21.53 ? 126 SER D N 1 ATOM 5917 C CA . SER D 2 126 ? 4.629 8.845 46.336 1.00 25.91 ? 126 SER D CA 1 ATOM 5918 C C . SER D 2 126 ? 4.864 7.345 46.375 1.00 24.23 ? 126 SER D C 1 ATOM 5919 O O . SER D 2 126 ? 3.959 6.570 46.043 1.00 22.68 ? 126 SER D O 1 ATOM 5920 C CB . SER D 2 126 ? 3.894 9.307 47.585 1.00 20.79 ? 126 SER D CB 1 ATOM 5921 O OG . SER D 2 126 ? 3.394 10.616 47.382 1.00 33.50 ? 126 SER D OG 1 ATOM 5922 N N . VAL D 2 127 ? 6.080 6.937 46.736 1.00 18.78 ? 127 VAL D N 1 ATOM 5923 C CA . VAL D 2 127 ? 6.406 5.520 46.808 1.00 17.88 ? 127 VAL D CA 1 ATOM 5924 C C . VAL D 2 127 ? 6.641 5.098 48.252 1.00 22.23 ? 127 VAL D C 1 ATOM 5925 O O . VAL D 2 127 ? 7.415 5.716 48.960 1.00 19.05 ? 127 VAL D O 1 ATOM 5926 C CB . VAL D 2 127 ? 7.630 5.190 45.964 1.00 15.59 ? 127 VAL D CB 1 ATOM 5927 C CG1 . VAL D 2 127 ? 7.849 3.678 45.922 1.00 13.46 ? 127 VAL D CG1 1 ATOM 5928 C CG2 . VAL D 2 127 ? 7.472 5.756 44.560 1.00 15.44 ? 127 VAL D CG2 1 ATOM 5929 N N . PHE D 2 128 ? 5.955 4.040 48.674 1.00 20.01 ? 128 PHE D N 1 ATOM 5930 C CA . PHE D 2 128 ? 6.040 3.550 50.032 1.00 13.41 ? 128 PHE D CA 1 ATOM 5931 C C . PHE D 2 128 ? 6.372 2.078 49.990 1.00 21.76 ? 128 PHE D C 1 ATOM 5932 O O . PHE D 2 128 ? 5.977 1.381 49.056 1.00 20.73 ? 128 PHE D O 1 ATOM 5933 C CB . PHE D 2 128 ? 4.710 3.749 50.762 1.00 18.72 ? 128 PHE D CB 1 ATOM 5934 C CG . PHE D 2 128 ? 4.242 5.174 50.809 1.00 16.76 ? 128 PHE D CG 1 ATOM 5935 C CD1 . PHE D 2 128 ? 5.011 6.155 51.419 1.00 16.73 ? 128 PHE D CD1 1 ATOM 5936 C CD2 . PHE D 2 128 ? 3.026 5.533 50.257 1.00 14.24 ? 128 PHE D CD2 1 ATOM 5937 C CE1 . PHE D 2 128 ? 4.572 7.487 51.474 1.00 16.34 ? 128 PHE D CE1 1 ATOM 5938 C CE2 . PHE D 2 128 ? 2.589 6.871 50.309 1.00 25.54 ? 128 PHE D CE2 1 ATOM 5939 C CZ . PHE D 2 128 ? 3.372 7.842 50.927 1.00 12.41 ? 128 PHE D CZ 1 ATOM 5940 N N . PRO D 2 129 ? 7.114 1.593 51.002 1.00 31.56 ? 129 PRO D N 1 ATOM 5941 C CA . PRO D 2 129 ? 7.519 0.186 51.102 1.00 20.82 ? 129 PRO D CA 1 ATOM 5942 C C . PRO D 2 129 ? 6.372 -0.722 51.525 1.00 20.92 ? 129 PRO D C 1 ATOM 5943 O O . PRO D 2 129 ? 5.607 -0.342 52.402 1.00 16.73 ? 129 PRO D O 1 ATOM 5944 C CB . PRO D 2 129 ? 8.545 0.217 52.239 1.00 18.91 ? 129 PRO D CB 1 ATOM 5945 C CG . PRO D 2 129 ? 8.095 1.355 53.095 1.00 19.18 ? 129 PRO D CG 1 ATOM 5946 C CD . PRO D 2 129 ? 7.654 2.394 52.118 1.00 18.92 ? 129 PRO D CD 1 ATOM 5947 N N . LEU D 2 130 ? 6.264 -1.903 50.922 1.00 21.31 ? 130 LEU D N 1 ATOM 5948 C CA . LEU D 2 130 ? 5.398 -2.946 51.460 1.00 20.53 ? 130 LEU D CA 1 ATOM 5949 C C . LEU D 2 130 ? 6.320 -3.984 52.062 1.00 21.51 ? 130 LEU D C 1 ATOM 5950 O O . LEU D 2 130 ? 6.853 -4.855 51.364 1.00 23.92 ? 130 LEU D O 1 ATOM 5951 C CB . LEU D 2 130 ? 4.493 -3.559 50.390 1.00 19.41 ? 130 LEU D CB 1 ATOM 5952 C CG . LEU D 2 130 ? 3.407 -2.657 49.784 1.00 22.29 ? 130 LEU D CG 1 ATOM 5953 C CD1 . LEU D 2 130 ? 2.851 -3.285 48.530 1.00 25.78 ? 130 LEU D CD1 1 ATOM 5954 C CD2 . LEU D 2 130 ? 2.276 -2.390 50.762 1.00 19.54 ? 130 LEU D CD2 1 ATOM 5955 N N . ALA D 2 131 ? 6.513 -3.871 53.370 1.00 21.56 ? 131 ALA D N 1 ATOM 5956 C CA . ALA D 2 131 ? 7.561 -4.599 54.061 1.00 21.95 ? 131 ALA D CA 1 ATOM 5957 C C . ALA D 2 131 ? 7.018 -5.679 54.969 1.00 27.88 ? 131 ALA D C 1 ATOM 5958 O O . ALA D 2 131 ? 6.031 -5.473 55.677 1.00 27.88 ? 131 ALA D O 1 ATOM 5959 C CB . ALA D 2 131 ? 8.395 -3.644 54.864 1.00 27.77 ? 131 ALA D CB 1 ATOM 5960 N N . PRO D 2 132 ? 7.684 -6.839 54.961 1.00 36.39 ? 132 PRO D N 1 ATOM 5961 C CA . PRO D 2 132 ? 7.416 -7.959 55.867 1.00 27.51 ? 132 PRO D CA 1 ATOM 5962 C C . PRO D 2 132 ? 8.005 -7.700 57.249 1.00 28.90 ? 132 PRO D C 1 ATOM 5963 O O . PRO D 2 132 ? 7.552 -8.313 58.218 1.00 50.44 ? 132 PRO D O 1 ATOM 5964 C CB . PRO D 2 132 ? 8.142 -9.117 55.195 1.00 29.02 ? 132 PRO D CB 1 ATOM 5965 C CG . PRO D 2 132 ? 9.297 -8.468 54.481 1.00 34.55 ? 132 PRO D CG 1 ATOM 5966 C CD . PRO D 2 132 ? 8.777 -7.129 54.018 1.00 29.53 ? 132 PRO D CD 1 ATOM 5967 N N . GLY D 2 140 ? 9.460 -20.319 54.370 1.00 29.26 ? 140 GLY D N 1 ATOM 5968 C CA . GLY D 2 140 ? 10.329 -19.169 54.544 1.00 29.21 ? 140 GLY D CA 1 ATOM 5969 C C . GLY D 2 140 ? 10.377 -18.280 53.312 1.00 29.55 ? 140 GLY D C 1 ATOM 5970 O O . GLY D 2 140 ? 11.449 -17.800 52.913 1.00 28.65 ? 140 GLY D O 1 ATOM 5971 N N . THR D 2 141 ? 9.215 -18.069 52.694 1.00 17.72 ? 141 THR D N 1 ATOM 5972 C CA . THR D 2 141 ? 9.109 -17.124 51.588 1.00 17.91 ? 141 THR D CA 1 ATOM 5973 C C . THR D 2 141 ? 8.525 -15.827 52.111 1.00 22.43 ? 141 THR D C 1 ATOM 5974 O O . THR D 2 141 ? 7.528 -15.824 52.817 1.00 24.01 ? 141 THR D O 1 ATOM 5975 C CB . THR D 2 141 ? 8.203 -17.628 50.451 1.00 24.91 ? 141 THR D CB 1 ATOM 5976 O OG1 . THR D 2 141 ? 8.824 -18.742 49.788 1.00 27.61 ? 141 THR D OG1 1 ATOM 5977 C CG2 . THR D 2 141 ? 7.967 -16.521 49.454 1.00 18.52 ? 141 THR D CG2 1 ATOM 5978 N N . ALA D 2 142 ? 9.161 -14.719 51.777 1.00 21.99 ? 142 ALA D N 1 ATOM 5979 C CA . ALA D 2 142 ? 8.649 -13.428 52.169 1.00 21.22 ? 142 ALA D CA 1 ATOM 5980 C C . ALA D 2 142 ? 8.110 -12.703 50.941 1.00 26.02 ? 142 ALA D C 1 ATOM 5981 O O . ALA D 2 142 ? 8.498 -12.997 49.804 1.00 19.07 ? 142 ALA D O 1 ATOM 5982 C CB . ALA D 2 142 ? 9.731 -12.614 52.834 1.00 19.67 ? 142 ALA D CB 1 ATOM 5983 N N . ALA D 2 143 ? 7.214 -11.753 51.172 1.00 22.93 ? 143 ALA D N 1 ATOM 5984 C CA . ALA D 2 143 ? 6.722 -10.920 50.095 1.00 18.03 ? 143 ALA D CA 1 ATOM 5985 C C . ALA D 2 143 ? 7.149 -9.513 50.407 1.00 18.87 ? 143 ALA D C 1 ATOM 5986 O O . ALA D 2 143 ? 7.162 -9.113 51.553 1.00 22.78 ? 143 ALA D O 1 ATOM 5987 C CB . ALA D 2 143 ? 5.197 -11.024 49.977 1.00 21.00 ? 143 ALA D CB 1 ATOM 5988 N N . LEU D 2 144 ? 7.513 -8.771 49.376 1.00 19.86 ? 144 LEU D N 1 ATOM 5989 C CA . LEU D 2 144 ? 8.022 -7.427 49.524 1.00 22.73 ? 144 LEU D CA 1 ATOM 5990 C C . LEU D 2 144 ? 7.338 -6.650 48.451 1.00 19.75 ? 144 LEU D C 1 ATOM 5991 O O . LEU D 2 144 ? 7.016 -7.213 47.404 1.00 15.16 ? 144 LEU D O 1 ATOM 5992 C CB . LEU D 2 144 ? 9.519 -7.386 49.228 1.00 26.08 ? 144 LEU D CB 1 ATOM 5993 C CG . LEU D 2 144 ? 10.505 -7.892 50.253 1.00 27.63 ? 144 LEU D CG 1 ATOM 5994 C CD1 . LEU D 2 144 ? 11.816 -8.151 49.560 1.00 29.30 ? 144 LEU D CD1 1 ATOM 5995 C CD2 . LEU D 2 144 ? 10.686 -6.829 51.269 1.00 37.29 ? 144 LEU D CD2 1 ATOM 5996 N N . GLY D 2 145 ? 7.151 -5.354 48.671 1.00 19.71 ? 145 GLY D N 1 ATOM 5997 C CA . GLY D 2 145 ? 6.564 -4.554 47.623 1.00 15.44 ? 145 GLY D CA 1 ATOM 5998 C C . GLY D 2 145 ? 6.723 -3.057 47.720 1.00 16.85 ? 145 GLY D C 1 ATOM 5999 O O . GLY D 2 145 ? 7.336 -2.542 48.659 1.00 17.60 ? 145 GLY D O 1 ATOM 6000 N N . CYS D 2 146 ? 6.164 -2.372 46.722 1.00 15.49 ? 146 CYS D N 1 ATOM 6001 C CA . CYS D 2 146 ? 6.151 -0.919 46.645 1.00 20.20 ? 146 CYS D CA 1 ATOM 6002 C C . CYS D 2 146 ? 4.750 -0.424 46.321 1.00 23.41 ? 146 CYS D C 1 ATOM 6003 O O . CYS D 2 146 ? 4.088 -0.934 45.417 1.00 18.06 ? 146 CYS D O 1 ATOM 6004 C CB . CYS D 2 146 ? 7.133 -0.404 45.586 1.00 20.83 ? 146 CYS D CB 1 ATOM 6005 S SG . CYS D 2 146 ? 8.835 -0.269 46.183 1.00 36.48 ? 146 CYS D SG 1 ATOM 6006 N N . LEU D 2 147 ? 4.311 0.574 47.077 1.00 26.41 ? 147 LEU D N 1 ATOM 6007 C CA . LEU D 2 147 ? 3.011 1.188 46.882 1.00 19.83 ? 147 LEU D CA 1 ATOM 6008 C C . LEU D 2 147 ? 3.231 2.500 46.160 1.00 19.85 ? 147 LEU D C 1 ATOM 6009 O O . LEU D 2 147 ? 3.822 3.440 46.700 1.00 19.94 ? 147 LEU D O 1 ATOM 6010 C CB . LEU D 2 147 ? 2.335 1.422 48.232 1.00 21.15 ? 147 LEU D CB 1 ATOM 6011 C CG . LEU D 2 147 ? 0.951 2.065 48.261 1.00 21.91 ? 147 LEU D CG 1 ATOM 6012 C CD1 . LEU D 2 147 ? -0.043 1.241 47.476 1.00 17.33 ? 147 LEU D CD1 1 ATOM 6013 C CD2 . LEU D 2 147 ? 0.516 2.190 49.700 1.00 20.91 ? 147 LEU D CD2 1 ATOM 6014 N N . VAL D 2 148 ? 2.804 2.538 44.907 1.00 20.53 ? 148 VAL D N 1 ATOM 6015 C CA . VAL D 2 148 ? 2.984 3.710 44.067 1.00 16.84 ? 148 VAL D CA 1 ATOM 6016 C C . VAL D 2 148 ? 1.663 4.456 44.048 1.00 23.13 ? 148 VAL D C 1 ATOM 6017 O O . VAL D 2 148 ? 0.700 4.033 43.404 1.00 24.66 ? 148 VAL D O 1 ATOM 6018 C CB . VAL D 2 148 ? 3.437 3.301 42.665 1.00 20.91 ? 148 VAL D CB 1 ATOM 6019 C CG1 . VAL D 2 148 ? 3.723 4.523 41.820 1.00 19.90 ? 148 VAL D CG1 1 ATOM 6020 C CG2 . VAL D 2 148 ? 4.681 2.409 42.770 1.00 12.57 ? 148 VAL D CG2 1 ATOM 6021 N N . LYS D 2 149 ? 1.619 5.562 44.782 1.00 20.42 ? 149 LYS D N 1 ATOM 6022 C CA . LYS D 2 149 ? 0.350 6.151 45.175 1.00 19.35 ? 149 LYS D CA 1 ATOM 6023 C C . LYS D 2 149 ? 0.166 7.612 44.770 1.00 18.50 ? 149 LYS D C 1 ATOM 6024 O O . LYS D 2 149 ? 1.083 8.420 44.874 1.00 20.45 ? 149 LYS D O 1 ATOM 6025 C CB . LYS D 2 149 ? 0.172 5.998 46.692 1.00 27.95 ? 149 LYS D CB 1 ATOM 6026 C CG . LYS D 2 149 ? -1.198 6.397 47.202 1.00 25.57 ? 149 LYS D CG 1 ATOM 6027 C CD . LYS D 2 149 ? -1.473 5.819 48.567 1.00 26.37 ? 149 LYS D CD 1 ATOM 6028 C CE . LYS D 2 149 ? -2.932 6.000 48.922 1.00 19.17 ? 149 LYS D CE 1 ATOM 6029 N NZ . LYS D 2 149 ? -3.303 7.429 48.802 1.00 28.63 ? 149 LYS D NZ 1 ATOM 6030 N N . ASP D 2 150 ? -1.044 7.923 44.308 1.00 23.18 ? 150 ASP D N 1 ATOM 6031 C CA . ASP D 2 150 ? -1.500 9.297 44.071 1.00 21.57 ? 150 ASP D CA 1 ATOM 6032 C C . ASP D 2 150 ? -0.736 9.975 42.944 1.00 22.74 ? 150 ASP D C 1 ATOM 6033 O O . ASP D 2 150 ? -0.148 11.049 43.127 1.00 22.60 ? 150 ASP D O 1 ATOM 6034 C CB . ASP D 2 150 ? -1.431 10.146 45.348 1.00 17.62 ? 150 ASP D CB 1 ATOM 6035 C CG . ASP D 2 150 ? -2.366 9.644 46.437 1.00 24.19 ? 150 ASP D CG 1 ATOM 6036 O OD1 . ASP D 2 150 ? -3.398 9.011 46.112 1.00 27.06 ? 150 ASP D OD1 1 ATOM 6037 O OD2 . ASP D 2 150 ? -2.077 9.886 47.626 1.00 26.45 ? 150 ASP D OD2 1 ATOM 6038 N N . TYR D 2 151 ? -0.754 9.342 41.775 1.00 19.39 ? 151 TYR D N 1 ATOM 6039 C CA . TYR D 2 151 ? -0.175 9.934 40.597 1.00 12.27 ? 151 TYR D CA 1 ATOM 6040 C C . TYR D 2 151 ? -1.232 10.079 39.509 1.00 20.87 ? 151 TYR D C 1 ATOM 6041 O O . TYR D 2 151 ? -2.267 9.407 39.531 1.00 25.48 ? 151 TYR D O 1 ATOM 6042 C CB . TYR D 2 151 ? 0.998 9.098 40.101 1.00 15.34 ? 151 TYR D CB 1 ATOM 6043 C CG . TYR D 2 151 ? 0.631 7.728 39.572 1.00 17.56 ? 151 TYR D CG 1 ATOM 6044 C CD1 . TYR D 2 151 ? 0.587 6.615 40.413 1.00 12.87 ? 151 TYR D CD1 1 ATOM 6045 C CD2 . TYR D 2 151 ? 0.353 7.538 38.223 1.00 13.69 ? 151 TYR D CD2 1 ATOM 6046 C CE1 . TYR D 2 151 ? 0.265 5.362 39.927 1.00 11.66 ? 151 TYR D CE1 1 ATOM 6047 C CE2 . TYR D 2 151 ? 0.040 6.289 37.733 1.00 20.55 ? 151 TYR D CE2 1 ATOM 6048 C CZ . TYR D 2 151 ? -0.005 5.202 38.586 1.00 16.81 ? 151 TYR D CZ 1 ATOM 6049 O OH . TYR D 2 151 ? -0.326 3.965 38.066 1.00 20.66 ? 151 TYR D OH 1 ATOM 6050 N N . PHE D 2 152 ? -0.954 10.967 38.563 1.00 15.46 ? 152 PHE D N 1 ATOM 6051 C CA . PHE D 2 152 ? -1.789 11.157 37.396 1.00 19.12 ? 152 PHE D CA 1 ATOM 6052 C C . PHE D 2 152 ? -0.951 11.801 36.293 1.00 21.48 ? 152 PHE D C 1 ATOM 6053 O O . PHE D 2 152 ? -0.135 12.681 36.558 1.00 22.43 ? 152 PHE D O 1 ATOM 6054 C CB . PHE D 2 152 ? -2.983 12.063 37.720 1.00 18.36 ? 152 PHE D CB 1 ATOM 6055 C CG . PHE D 2 152 ? -4.035 12.074 36.647 1.00 25.42 ? 152 PHE D CG 1 ATOM 6056 C CD1 . PHE D 2 152 ? -3.999 13.014 35.619 1.00 23.23 ? 152 PHE D CD1 1 ATOM 6057 C CD2 . PHE D 2 152 ? -5.043 11.125 36.648 1.00 18.95 ? 152 PHE D CD2 1 ATOM 6058 C CE1 . PHE D 2 152 ? -4.969 13.015 34.628 1.00 22.35 ? 152 PHE D CE1 1 ATOM 6059 C CE2 . PHE D 2 152 ? -6.007 11.113 35.653 1.00 25.89 ? 152 PHE D CE2 1 ATOM 6060 C CZ . PHE D 2 152 ? -5.976 12.063 34.649 1.00 16.07 ? 152 PHE D CZ 1 ATOM 6061 N N . PRO D 2 153 ? -1.141 11.359 35.048 1.00 17.90 ? 153 PRO D N 1 ATOM 6062 C CA . PRO D 2 153 ? -2.013 10.254 34.648 1.00 21.43 ? 153 PRO D CA 1 ATOM 6063 C C . PRO D 2 153 ? -1.241 8.946 34.610 1.00 18.74 ? 153 PRO D C 1 ATOM 6064 O O . PRO D 2 153 ? -0.089 8.888 35.014 1.00 15.83 ? 153 PRO D O 1 ATOM 6065 C CB . PRO D 2 153 ? -2.391 10.632 33.218 1.00 21.40 ? 153 PRO D CB 1 ATOM 6066 C CG . PRO D 2 153 ? -1.123 11.271 32.696 1.00 20.12 ? 153 PRO D CG 1 ATOM 6067 C CD . PRO D 2 153 ? -0.557 12.046 33.882 1.00 19.90 ? 153 PRO D CD 1 ATOM 6068 N N . GLU D 2 154 ? -1.880 7.903 34.102 1.00 22.07 ? 154 GLU D N 1 ATOM 6069 C CA . GLU D 2 154 ? -1.169 6.684 33.749 1.00 21.99 ? 154 GLU D CA 1 ATOM 6070 C C . GLU D 2 154 ? -0.186 7.019 32.610 1.00 26.30 ? 154 GLU D C 1 ATOM 6071 O O . GLU D 2 154 ? -0.340 8.049 31.942 1.00 21.46 ? 154 GLU D O 1 ATOM 6072 C CB . GLU D 2 154 ? -2.176 5.631 33.290 1.00 20.96 ? 154 GLU D CB 1 ATOM 6073 C CG . GLU D 2 154 ? -2.889 4.894 34.407 1.00 24.19 ? 154 GLU D CG 1 ATOM 6074 C CD . GLU D 2 154 ? -2.192 3.598 34.743 1.00 39.27 ? 154 GLU D CD 1 ATOM 6075 O OE1 . GLU D 2 154 ? -2.772 2.563 34.385 1.00 42.48 ? 154 GLU D OE1 1 ATOM 6076 O OE2 . GLU D 2 154 ? -1.083 3.605 35.363 1.00 38.69 ? 154 GLU D OE2 1 ATOM 6077 N N . PRO D 2 155 ? 0.852 6.183 32.405 1.00 24.47 ? 155 PRO D N 1 ATOM 6078 C CA . PRO D 2 155 ? 1.241 5.020 33.210 1.00 22.90 ? 155 PRO D CA 1 ATOM 6079 C C . PRO D 2 155 ? 2.454 5.304 34.092 1.00 24.56 ? 155 PRO D C 1 ATOM 6080 O O . PRO D 2 155 ? 3.119 6.343 33.989 1.00 19.07 ? 155 PRO D O 1 ATOM 6081 C CB . PRO D 2 155 ? 1.673 4.032 32.141 1.00 18.02 ? 155 PRO D CB 1 ATOM 6082 C CG . PRO D 2 155 ? 2.404 4.943 31.152 1.00 18.69 ? 155 PRO D CG 1 ATOM 6083 C CD . PRO D 2 155 ? 1.644 6.254 31.163 1.00 19.16 ? 155 PRO D CD 1 ATOM 6084 N N . VAL D 2 156 ? 2.762 4.353 34.957 1.00 27.33 ? 156 VAL D N 1 ATOM 6085 C CA . VAL D 2 156 ? 4.003 4.411 35.699 1.00 23.36 ? 156 VAL D CA 1 ATOM 6086 C C . VAL D 2 156 ? 4.659 3.067 35.445 1.00 23.86 ? 156 VAL D C 1 ATOM 6087 O O . VAL D 2 156 ? 3.962 2.064 35.283 1.00 25.30 ? 156 VAL D O 1 ATOM 6088 C CB . VAL D 2 156 ? 3.744 4.673 37.211 1.00 24.28 ? 156 VAL D CB 1 ATOM 6089 C CG1 . VAL D 2 156 ? 3.085 3.491 37.854 1.00 21.89 ? 156 VAL D CG1 1 ATOM 6090 C CG2 . VAL D 2 156 ? 5.035 5.010 37.933 1.00 23.20 ? 156 VAL D CG2 1 ATOM 6091 N N . THR D 2 157 ? 5.980 3.030 35.346 1.00 23.43 ? 157 THR D N 1 ATOM 6092 C CA . THR D 2 157 ? 6.636 1.736 35.193 1.00 25.36 ? 157 THR D CA 1 ATOM 6093 C C . THR D 2 157 ? 7.442 1.415 36.430 1.00 21.99 ? 157 THR D C 1 ATOM 6094 O O . THR D 2 157 ? 8.002 2.301 37.064 1.00 21.25 ? 157 THR D O 1 ATOM 6095 C CB . THR D 2 157 ? 7.589 1.701 34.008 1.00 26.62 ? 157 THR D CB 1 ATOM 6096 O OG1 . THR D 2 157 ? 8.690 2.568 34.288 1.00 26.75 ? 157 THR D OG1 1 ATOM 6097 C CG2 . THR D 2 157 ? 6.881 2.129 32.726 1.00 17.26 ? 157 THR D CG2 1 ATOM 6098 N N . VAL D 2 158 ? 7.482 0.132 36.768 1.00 22.27 ? 158 VAL D N 1 ATOM 6099 C CA . VAL D 2 158 ? 8.177 -0.336 37.955 1.00 18.69 ? 158 VAL D CA 1 ATOM 6100 C C . VAL D 2 158 ? 9.020 -1.544 37.617 1.00 23.53 ? 158 VAL D C 1 ATOM 6101 O O . VAL D 2 158 ? 8.536 -2.513 37.019 1.00 24.98 ? 158 VAL D O 1 ATOM 6102 C CB . VAL D 2 158 ? 7.205 -0.757 39.080 1.00 15.85 ? 158 VAL D CB 1 ATOM 6103 C CG1 . VAL D 2 158 ? 7.979 -1.135 40.341 1.00 13.40 ? 158 VAL D CG1 1 ATOM 6104 C CG2 . VAL D 2 158 ? 6.215 0.348 39.370 1.00 19.80 ? 158 VAL D CG2 1 ATOM 6105 N N . SER D 2 159 ? 10.283 -1.502 38.019 1.00 21.70 ? 159 SER D N 1 ATOM 6106 C CA . SER D 2 159 ? 11.141 -2.656 37.853 1.00 22.38 ? 159 SER D CA 1 ATOM 6107 C C . SER D 2 159 ? 11.774 -2.902 39.204 1.00 22.54 ? 159 SER D C 1 ATOM 6108 O O . SER D 2 159 ? 11.647 -2.077 40.098 1.00 23.18 ? 159 SER D O 1 ATOM 6109 C CB . SER D 2 159 ? 12.204 -2.390 36.778 1.00 17.81 ? 159 SER D CB 1 ATOM 6110 O OG . SER D 2 159 ? 13.105 -1.398 37.217 1.00 22.70 ? 159 SER D OG 1 ATOM 6111 N N . TRP D 2 160 ? 12.441 -4.037 39.358 1.00 24.63 ? 160 TRP D N 1 ATOM 6112 C CA . TRP D 2 160 ? 13.150 -4.341 40.589 1.00 16.51 ? 160 TRP D CA 1 ATOM 6113 C C . TRP D 2 160 ? 14.635 -4.597 40.328 1.00 20.87 ? 160 TRP D C 1 ATOM 6114 O O . TRP D 2 160 ? 14.990 -5.288 39.363 1.00 21.40 ? 160 TRP D O 1 ATOM 6115 C CB . TRP D 2 160 ? 12.529 -5.565 41.242 1.00 17.81 ? 160 TRP D CB 1 ATOM 6116 C CG . TRP D 2 160 ? 11.207 -5.284 41.843 1.00 28.22 ? 160 TRP D CG 1 ATOM 6117 C CD1 . TRP D 2 160 ? 9.983 -5.314 41.215 1.00 21.04 ? 160 TRP D CD1 1 ATOM 6118 C CD2 . TRP D 2 160 ? 10.954 -4.916 43.200 1.00 20.41 ? 160 TRP D CD2 1 ATOM 6119 N NE1 . TRP D 2 160 ? 8.994 -4.988 42.105 1.00 19.85 ? 160 TRP D NE1 1 ATOM 6120 C CE2 . TRP D 2 160 ? 9.558 -4.740 43.331 1.00 22.09 ? 160 TRP D CE2 1 ATOM 6121 C CE3 . TRP D 2 160 ? 11.771 -4.725 44.321 1.00 19.38 ? 160 TRP D CE3 1 ATOM 6122 C CZ2 . TRP D 2 160 ? 8.958 -4.376 44.548 1.00 20.67 ? 160 TRP D CZ2 1 ATOM 6123 C CZ3 . TRP D 2 160 ? 11.184 -4.359 45.517 1.00 18.02 ? 160 TRP D CZ3 1 ATOM 6124 C CH2 . TRP D 2 160 ? 9.786 -4.194 45.626 1.00 19.13 ? 160 TRP D CH2 1 ATOM 6125 N N . ASN D 2 161 ? 15.481 -4.048 41.203 1.00 19.39 ? 161 ASN D N 1 ATOM 6126 C CA . ASN D 2 161 ? 16.931 -4.224 41.133 1.00 25.36 ? 161 ASN D CA 1 ATOM 6127 C C . ASN D 2 161 ? 17.476 -3.887 39.749 1.00 22.61 ? 161 ASN D C 1 ATOM 6128 O O . ASN D 2 161 ? 18.221 -4.656 39.155 1.00 20.62 ? 161 ASN D O 1 ATOM 6129 C CB . ASN D 2 161 ? 17.332 -5.637 41.574 1.00 15.39 ? 161 ASN D CB 1 ATOM 6130 C CG . ASN D 2 161 ? 17.183 -5.841 43.069 1.00 16.88 ? 161 ASN D CG 1 ATOM 6131 O OD1 . ASN D 2 161 ? 16.768 -4.936 43.794 1.00 28.75 ? 161 ASN D OD1 1 ATOM 6132 N ND2 . ASN D 2 161 ? 17.520 -7.023 43.541 1.00 13.08 ? 161 ASN D ND2 1 ATOM 6133 N N . SER D 2 162 ? 17.060 -2.733 39.240 1.00 19.91 ? 162 SER D N 1 ATOM 6134 C CA . SER D 2 162 ? 17.407 -2.283 37.895 1.00 21.43 ? 162 SER D CA 1 ATOM 6135 C C . SER D 2 162 ? 17.142 -3.286 36.778 1.00 20.43 ? 162 SER D C 1 ATOM 6136 O O . SER D 2 162 ? 17.791 -3.235 35.740 1.00 24.63 ? 162 SER D O 1 ATOM 6137 C CB . SER D 2 162 ? 18.860 -1.818 37.842 1.00 21.64 ? 162 SER D CB 1 ATOM 6138 O OG . SER D 2 162 ? 19.084 -0.841 38.842 1.00 34.15 ? 162 SER D OG 1 ATOM 6139 N N . GLY D 2 163 ? 16.177 -4.173 36.974 1.00 19.02 ? 163 GLY D N 1 ATOM 6140 C CA . GLY D 2 163 ? 15.818 -5.129 35.941 1.00 17.17 ? 163 GLY D CA 1 ATOM 6141 C C . GLY D 2 163 ? 16.362 -6.527 36.193 1.00 26.70 ? 163 GLY D C 1 ATOM 6142 O O . GLY D 2 163 ? 15.901 -7.488 35.588 1.00 32.12 ? 163 GLY D O 1 ATOM 6143 N N . ALA D 2 164 ? 17.331 -6.647 37.097 1.00 23.15 ? 164 ALA D N 1 ATOM 6144 C CA . ALA D 2 164 ? 17.961 -7.936 37.379 1.00 21.78 ? 164 ALA D CA 1 ATOM 6145 C C . ALA D 2 164 ? 16.997 -8.915 38.021 1.00 23.89 ? 164 ALA D C 1 ATOM 6146 O O . ALA D 2 164 ? 17.271 -10.109 38.064 1.00 25.61 ? 164 ALA D O 1 ATOM 6147 C CB . ALA D 2 164 ? 19.183 -7.760 38.272 1.00 13.50 ? 164 ALA D CB 1 ATOM 6148 N N . LEU D 2 165 ? 15.889 -8.406 38.549 1.00 20.52 ? 165 LEU D N 1 ATOM 6149 C CA . LEU D 2 165 ? 14.962 -9.219 39.336 1.00 22.95 ? 165 LEU D CA 1 ATOM 6150 C C . LEU D 2 165 ? 13.582 -9.222 38.693 1.00 26.79 ? 165 LEU D C 1 ATOM 6151 O O . LEU D 2 165 ? 12.813 -8.257 38.804 1.00 25.74 ? 165 LEU D O 1 ATOM 6152 C CB . LEU D 2 165 ? 14.884 -8.700 40.784 1.00 17.40 ? 165 LEU D CB 1 ATOM 6153 C CG . LEU D 2 165 ? 13.882 -9.396 41.714 1.00 25.92 ? 165 LEU D CG 1 ATOM 6154 C CD1 . LEU D 2 165 ? 14.010 -10.901 41.611 1.00 21.65 ? 165 LEU D CD1 1 ATOM 6155 C CD2 . LEU D 2 165 ? 14.079 -8.947 43.166 1.00 20.95 ? 165 LEU D CD2 1 ATOM 6156 N N . THR D 2 166 ? 13.264 -10.315 38.019 1.00 20.06 ? 166 THR D N 1 ATOM 6157 C CA . THR D 2 166 ? 11.993 -10.407 37.322 1.00 23.93 ? 166 THR D CA 1 ATOM 6158 C C . THR D 2 166 ? 11.165 -11.563 37.861 1.00 22.60 ? 166 THR D C 1 ATOM 6159 O O . THR D 2 166 ? 9.936 -11.546 37.829 1.00 29.17 ? 166 THR D O 1 ATOM 6160 C CB . THR D 2 166 ? 12.238 -10.613 35.836 1.00 26.76 ? 166 THR D CB 1 ATOM 6161 O OG1 . THR D 2 166 ? 13.236 -11.628 35.681 1.00 25.06 ? 166 THR D OG1 1 ATOM 6162 C CG2 . THR D 2 166 ? 12.725 -9.317 35.192 1.00 19.51 ? 166 THR D CG2 1 ATOM 6163 N N . SER D 2 167 ? 11.847 -12.567 38.380 1.00 21.54 ? 167 SER D N 1 ATOM 6164 C CA . SER D 2 167 ? 11.177 -13.784 38.808 1.00 30.27 ? 167 SER D CA 1 ATOM 6165 C C . SER D 2 167 ? 10.335 -13.585 40.075 1.00 24.89 ? 167 SER D C 1 ATOM 6166 O O . SER D 2 167 ? 10.840 -13.139 41.114 1.00 30.60 ? 167 SER D O 1 ATOM 6167 C CB . SER D 2 167 ? 12.212 -14.890 39.014 1.00 35.37 ? 167 SER D CB 1 ATOM 6168 O OG . SER D 2 167 ? 11.582 -16.154 39.060 1.00 47.86 ? 167 SER D OG 1 ATOM 6169 N N . GLY D 2 168 ? 9.049 -13.906 39.983 1.00 26.01 ? 168 GLY D N 1 ATOM 6170 C CA . GLY D 2 168 ? 8.155 -13.761 41.119 1.00 21.12 ? 168 GLY D CA 1 ATOM 6171 C C . GLY D 2 168 ? 7.723 -12.322 41.356 1.00 23.78 ? 168 GLY D C 1 ATOM 6172 O O . GLY D 2 168 ? 7.118 -12.016 42.383 1.00 20.78 ? 168 GLY D O 1 ATOM 6173 N N . VAL D 2 169 ? 8.052 -11.438 40.413 1.00 19.09 ? 169 VAL D N 1 ATOM 6174 C CA . VAL D 2 169 ? 7.564 -10.068 40.434 1.00 19.28 ? 169 VAL D CA 1 ATOM 6175 C C . VAL D 2 169 ? 6.140 -10.016 39.888 1.00 17.79 ? 169 VAL D C 1 ATOM 6176 O O . VAL D 2 169 ? 5.839 -10.622 38.866 1.00 28.61 ? 169 VAL D O 1 ATOM 6177 C CB . VAL D 2 169 ? 8.462 -9.143 39.600 1.00 18.92 ? 169 VAL D CB 1 ATOM 6178 C CG1 . VAL D 2 169 ? 7.893 -7.739 39.567 1.00 18.18 ? 169 VAL D CG1 1 ATOM 6179 C CG2 . VAL D 2 169 ? 9.878 -9.133 40.146 1.00 14.39 ? 169 VAL D CG2 1 ATOM 6180 N N . HIS D 2 170 ? 5.250 -9.344 40.602 1.00 21.40 ? 170 HIS D N 1 ATOM 6181 C CA . HIS D 2 170 ? 3.919 -9.045 40.078 1.00 16.39 ? 170 HIS D CA 1 ATOM 6182 C C . HIS D 2 170 ? 3.705 -7.557 40.226 1.00 19.64 ? 170 HIS D C 1 ATOM 6183 O O . HIS D 2 170 ? 3.806 -7.013 41.328 1.00 19.41 ? 170 HIS D O 1 ATOM 6184 C CB . HIS D 2 170 ? 2.810 -9.785 40.831 1.00 13.66 ? 170 HIS D CB 1 ATOM 6185 C CG . HIS D 2 170 ? 2.835 -11.269 40.641 1.00 22.41 ? 170 HIS D CG 1 ATOM 6186 N ND1 . HIS D 2 170 ? 2.760 -11.863 39.396 1.00 27.93 ? 170 HIS D ND1 1 ATOM 6187 C CD2 . HIS D 2 170 ? 2.938 -12.280 41.536 1.00 19.99 ? 170 HIS D CD2 1 ATOM 6188 C CE1 . HIS D 2 170 ? 2.817 -13.175 39.534 1.00 20.65 ? 170 HIS D CE1 1 ATOM 6189 N NE2 . HIS D 2 170 ? 2.928 -13.454 40.821 1.00 25.59 ? 170 HIS D NE2 1 ATOM 6190 N N . THR D 2 171 ? 3.454 -6.895 39.106 1.00 15.90 ? 171 THR D N 1 ATOM 6191 C CA . THR D 2 171 ? 3.111 -5.490 39.123 1.00 18.41 ? 171 THR D CA 1 ATOM 6192 C C . THR D 2 171 ? 1.662 -5.346 38.709 1.00 19.53 ? 171 THR D C 1 ATOM 6193 O O . THR D 2 171 ? 1.278 -5.691 37.598 1.00 22.61 ? 171 THR D O 1 ATOM 6194 C CB . THR D 2 171 ? 4.033 -4.693 38.214 1.00 17.89 ? 171 THR D CB 1 ATOM 6195 O OG1 . THR D 2 171 ? 5.366 -4.799 38.726 1.00 24.29 ? 171 THR D OG1 1 ATOM 6196 C CG2 . THR D 2 171 ? 3.615 -3.234 38.187 1.00 15.65 ? 171 THR D CG2 1 ATOM 6197 N N . PHE D 2 172 ? 0.846 -4.864 39.629 1.00 23.19 ? 172 PHE D N 1 ATOM 6198 C CA . PHE D 2 172 ? -0.595 -4.863 39.424 1.00 19.14 ? 172 PHE D CA 1 ATOM 6199 C C . PHE D 2 172 ? -1.067 -3.735 38.496 1.00 21.32 ? 172 PHE D C 1 ATOM 6200 O O . PHE D 2 172 ? -0.379 -2.716 38.325 1.00 21.65 ? 172 PHE D O 1 ATOM 6201 C CB . PHE D 2 172 ? -1.305 -4.819 40.784 1.00 22.56 ? 172 PHE D CB 1 ATOM 6202 C CG . PHE D 2 172 ? -1.147 -6.084 41.586 1.00 16.60 ? 172 PHE D CG 1 ATOM 6203 C CD1 . PHE D 2 172 ? -2.031 -7.147 41.411 1.00 18.36 ? 172 PHE D CD1 1 ATOM 6204 C CD2 . PHE D 2 172 ? -0.117 -6.221 42.499 1.00 18.90 ? 172 PHE D CD2 1 ATOM 6205 C CE1 . PHE D 2 172 ? -1.894 -8.322 42.135 1.00 16.30 ? 172 PHE D CE1 1 ATOM 6206 C CE2 . PHE D 2 172 ? 0.022 -7.389 43.241 1.00 18.40 ? 172 PHE D CE2 1 ATOM 6207 C CZ . PHE D 2 172 ? -0.870 -8.436 43.061 1.00 25.33 ? 172 PHE D CZ 1 ATOM 6208 N N . PRO D 2 173 ? -2.232 -3.929 37.863 1.00 21.56 ? 173 PRO D N 1 ATOM 6209 C CA . PRO D 2 173 ? -2.797 -2.824 37.095 1.00 18.32 ? 173 PRO D CA 1 ATOM 6210 C C . PRO D 2 173 ? -3.170 -1.717 38.060 1.00 23.51 ? 173 PRO D C 1 ATOM 6211 O O . PRO D 2 173 ? -3.744 -2.014 39.113 1.00 22.11 ? 173 PRO D O 1 ATOM 6212 C CB . PRO D 2 173 ? -4.073 -3.426 36.500 1.00 12.01 ? 173 PRO D CB 1 ATOM 6213 C CG . PRO D 2 173 ? -3.910 -4.898 36.595 1.00 13.76 ? 173 PRO D CG 1 ATOM 6214 C CD . PRO D 2 173 ? -3.063 -5.144 37.786 1.00 19.74 ? 173 PRO D CD 1 ATOM 6215 N N . ALA D 2 174 ? -2.852 -0.474 37.708 1.00 20.89 ? 174 ALA D N 1 ATOM 6216 C CA . ALA D 2 174 ? -3.283 0.696 38.478 1.00 24.40 ? 174 ALA D CA 1 ATOM 6217 C C . ALA D 2 174 ? -4.798 0.725 38.695 1.00 21.50 ? 174 ALA D C 1 ATOM 6218 O O . ALA D 2 174 ? -5.572 0.371 37.804 1.00 20.64 ? 174 ALA D O 1 ATOM 6219 C CB . ALA D 2 174 ? -2.844 1.980 37.767 1.00 20.35 ? 174 ALA D CB 1 ATOM 6220 N N . VAL D 2 175 ? -5.215 1.170 39.871 1.00 17.51 ? 175 VAL D N 1 ATOM 6221 C CA . VAL D 2 175 ? -6.618 1.474 40.097 1.00 19.62 ? 175 VAL D CA 1 ATOM 6222 C C . VAL D 2 175 ? -6.829 2.975 40.180 1.00 22.80 ? 175 VAL D C 1 ATOM 6223 O O . VAL D 2 175 ? -5.960 3.715 40.657 1.00 24.42 ? 175 VAL D O 1 ATOM 6224 C CB . VAL D 2 175 ? -7.188 0.821 41.383 1.00 18.86 ? 175 VAL D CB 1 ATOM 6225 C CG1 . VAL D 2 175 ? -6.954 -0.678 41.366 1.00 14.47 ? 175 VAL D CG1 1 ATOM 6226 C CG2 . VAL D 2 175 ? -6.617 1.484 42.658 1.00 23.57 ? 175 VAL D CG2 1 ATOM 6227 N N . LEU D 2 176 ? -7.989 3.413 39.696 1.00 21.27 ? 176 LEU D N 1 ATOM 6228 C CA . LEU D 2 176 ? -8.431 4.780 39.861 1.00 16.75 ? 176 LEU D CA 1 ATOM 6229 C C . LEU D 2 176 ? -9.081 4.966 41.242 1.00 20.83 ? 176 LEU D C 1 ATOM 6230 O O . LEU D 2 176 ? -10.066 4.306 41.580 1.00 24.16 ? 176 LEU D O 1 ATOM 6231 C CB . LEU D 2 176 ? -9.399 5.146 38.739 1.00 22.14 ? 176 LEU D CB 1 ATOM 6232 C CG . LEU D 2 176 ? -9.809 6.619 38.657 1.00 25.88 ? 176 LEU D CG 1 ATOM 6233 C CD1 . LEU D 2 176 ? -8.598 7.527 38.837 1.00 22.52 ? 176 LEU D CD1 1 ATOM 6234 C CD2 . LEU D 2 176 ? -10.476 6.884 37.329 1.00 15.96 ? 176 LEU D CD2 1 ATOM 6235 N N . GLN D 2 177 ? -8.505 5.852 42.050 1.00 24.35 ? 177 GLN D N 1 ATOM 6236 C CA . GLN D 2 177 ? -9.022 6.127 43.389 1.00 20.17 ? 177 GLN D CA 1 ATOM 6237 C C . GLN D 2 177 ? -10.171 7.122 43.336 1.00 25.25 ? 177 GLN D C 1 ATOM 6238 O O . GLN D 2 177 ? -10.321 7.848 42.357 1.00 28.91 ? 177 GLN D O 1 ATOM 6239 C CB . GLN D 2 177 ? -7.920 6.692 44.270 1.00 19.41 ? 177 GLN D CB 1 ATOM 6240 C CG . GLN D 2 177 ? -6.959 5.673 44.798 1.00 18.92 ? 177 GLN D CG 1 ATOM 6241 C CD . GLN D 2 177 ? -5.600 6.275 45.056 1.00 23.83 ? 177 GLN D CD 1 ATOM 6242 O OE1 . GLN D 2 177 ? -4.884 5.852 45.953 1.00 30.05 ? 177 GLN D OE1 1 ATOM 6243 N NE2 . GLN D 2 177 ? -5.237 7.273 44.262 1.00 24.29 ? 177 GLN D NE2 1 ATOM 6244 N N . SER D 2 178 ? -10.966 7.186 44.400 1.00 28.95 ? 178 SER D N 1 ATOM 6245 C CA . SER D 2 178 ? -12.112 8.086 44.414 1.00 26.56 ? 178 SER D CA 1 ATOM 6246 C C . SER D 2 178 ? -11.635 9.528 44.272 1.00 25.79 ? 178 SER D C 1 ATOM 6247 O O . SER D 2 178 ? -12.379 10.405 43.846 1.00 38.40 ? 178 SER D O 1 ATOM 6248 C CB . SER D 2 178 ? -12.948 7.897 45.683 1.00 35.48 ? 178 SER D CB 1 ATOM 6249 O OG . SER D 2 178 ? -12.252 8.310 46.844 1.00 51.28 ? 178 SER D OG 1 ATOM 6250 N N . SER D 2 179 ? -10.371 9.752 44.600 1.00 25.52 ? 179 SER D N 1 ATOM 6251 C CA . SER D 2 179 ? -9.758 11.067 44.507 1.00 18.02 ? 179 SER D CA 1 ATOM 6252 C C . SER D 2 179 ? -9.448 11.446 43.065 1.00 22.85 ? 179 SER D C 1 ATOM 6253 O O . SER D 2 179 ? -9.171 12.611 42.776 1.00 24.66 ? 179 SER D O 1 ATOM 6254 C CB . SER D 2 179 ? -8.454 11.079 45.306 1.00 17.95 ? 179 SER D CB 1 ATOM 6255 O OG . SER D 2 179 ? -7.444 10.369 44.609 1.00 23.54 ? 179 SER D OG 1 ATOM 6256 N N . GLY D 2 180 ? -9.455 10.460 42.170 1.00 23.15 ? 180 GLY D N 1 ATOM 6257 C CA . GLY D 2 180 ? -9.111 10.698 40.775 1.00 20.76 ? 180 GLY D CA 1 ATOM 6258 C C . GLY D 2 180 ? -7.643 10.475 40.438 1.00 21.08 ? 180 GLY D C 1 ATOM 6259 O O . GLY D 2 180 ? -7.236 10.561 39.284 1.00 23.05 ? 180 GLY D O 1 ATOM 6260 N N . LEU D 2 181 ? -6.844 10.187 41.454 1.00 22.58 ? 181 LEU D N 1 ATOM 6261 C CA . LEU D 2 181 ? -5.443 9.861 41.256 1.00 21.38 ? 181 LEU D CA 1 ATOM 6262 C C . LEU D 2 181 ? -5.323 8.346 41.155 1.00 20.58 ? 181 LEU D C 1 ATOM 6263 O O . LEU D 2 181 ? -6.201 7.628 41.647 1.00 21.61 ? 181 LEU D O 1 ATOM 6264 C CB . LEU D 2 181 ? -4.617 10.395 42.435 1.00 22.77 ? 181 LEU D CB 1 ATOM 6265 C CG . LEU D 2 181 ? -4.727 11.908 42.659 1.00 20.40 ? 181 LEU D CG 1 ATOM 6266 C CD1 . LEU D 2 181 ? -3.964 12.364 43.899 1.00 16.03 ? 181 LEU D CD1 1 ATOM 6267 C CD2 . LEU D 2 181 ? -4.253 12.663 41.395 1.00 16.24 ? 181 LEU D CD2 1 ATOM 6268 N N . TYR D 2 182 ? -4.265 7.848 40.508 1.00 17.45 ? 182 TYR D N 1 ATOM 6269 C CA . TYR D 2 182 ? -4.068 6.397 40.448 1.00 20.65 ? 182 TYR D CA 1 ATOM 6270 C C . TYR D 2 182 ? -3.212 5.887 41.589 1.00 19.53 ? 182 TYR D C 1 ATOM 6271 O O . TYR D 2 182 ? -2.483 6.641 42.229 1.00 17.32 ? 182 TYR D O 1 ATOM 6272 C CB . TYR D 2 182 ? -3.449 5.934 39.127 1.00 12.06 ? 182 TYR D CB 1 ATOM 6273 C CG . TYR D 2 182 ? -4.375 6.050 37.950 1.00 20.09 ? 182 TYR D CG 1 ATOM 6274 C CD1 . TYR D 2 182 ? -4.384 7.197 37.176 1.00 25.24 ? 182 TYR D CD1 1 ATOM 6275 C CD2 . TYR D 2 182 ? -5.235 5.019 37.603 1.00 17.03 ? 182 TYR D CD2 1 ATOM 6276 C CE1 . TYR D 2 182 ? -5.221 7.330 36.106 1.00 19.49 ? 182 TYR D CE1 1 ATOM 6277 C CE2 . TYR D 2 182 ? -6.087 5.145 36.524 1.00 16.80 ? 182 TYR D CE2 1 ATOM 6278 C CZ . TYR D 2 182 ? -6.067 6.309 35.781 1.00 21.36 ? 182 TYR D CZ 1 ATOM 6279 O OH . TYR D 2 182 ? -6.887 6.479 34.703 1.00 26.14 ? 182 TYR D OH 1 ATOM 6280 N N . SER D 2 183 ? -3.299 4.585 41.810 1.00 14.44 ? 183 SER D N 1 ATOM 6281 C CA . SER D 2 183 ? -2.435 3.914 42.742 1.00 15.54 ? 183 SER D CA 1 ATOM 6282 C C . SER D 2 183 ? -2.132 2.550 42.158 1.00 20.41 ? 183 SER D C 1 ATOM 6283 O O . SER D 2 183 ? -2.969 1.979 41.469 1.00 15.76 ? 183 SER D O 1 ATOM 6284 C CB . SER D 2 183 ? -3.147 3.746 44.071 1.00 15.05 ? 183 SER D CB 1 ATOM 6285 O OG . SER D 2 183 ? -2.214 3.654 45.121 1.00 32.77 ? 183 SER D OG 1 ATOM 6286 N N . LEU D 2 184 ? -0.926 2.041 42.399 1.00 22.59 ? 184 LEU D N 1 ATOM 6287 C CA . LEU D 2 184 ? -0.632 0.641 42.107 1.00 22.13 ? 184 LEU D CA 1 ATOM 6288 C C . LEU D 2 184 ? 0.374 0.083 43.069 1.00 18.92 ? 184 LEU D C 1 ATOM 6289 O O . LEU D 2 184 ? 1.030 0.821 43.797 1.00 22.96 ? 184 LEU D O 1 ATOM 6290 C CB . LEU D 2 184 ? -0.171 0.409 40.659 1.00 18.90 ? 184 LEU D CB 1 ATOM 6291 C CG . LEU D 2 184 ? 1.116 0.939 40.029 1.00 21.73 ? 184 LEU D CG 1 ATOM 6292 C CD1 . LEU D 2 184 ? 2.370 0.200 40.452 1.00 15.86 ? 184 LEU D CD1 1 ATOM 6293 C CD2 . LEU D 2 184 ? 0.942 0.817 38.534 1.00 23.63 ? 184 LEU D CD2 1 ATOM 6294 N N . SER D 2 185 ? 0.470 -1.238 43.077 1.00 22.61 ? 185 SER D N 1 ATOM 6295 C CA . SER D 2 185 ? 1.463 -1.920 43.877 1.00 21.10 ? 185 SER D CA 1 ATOM 6296 C C . SER D 2 185 ? 2.224 -2.871 42.990 1.00 21.50 ? 185 SER D C 1 ATOM 6297 O O . SER D 2 185 ? 1.700 -3.352 41.974 1.00 15.55 ? 185 SER D O 1 ATOM 6298 C CB . SER D 2 185 ? 0.822 -2.678 45.024 1.00 22.96 ? 185 SER D CB 1 ATOM 6299 O OG . SER D 2 185 ? 0.292 -1.781 45.978 1.00 38.11 ? 185 SER D OG 1 ATOM 6300 N N . SER D 2 186 ? 3.477 -3.099 43.373 1.00 16.25 ? 186 SER D N 1 ATOM 6301 C CA . SER D 2 186 ? 4.320 -4.094 42.746 1.00 15.97 ? 186 SER D CA 1 ATOM 6302 C C . SER D 2 186 ? 4.954 -4.894 43.859 1.00 15.37 ? 186 SER D C 1 ATOM 6303 O O . SER D 2 186 ? 5.537 -4.331 44.780 1.00 11.97 ? 186 SER D O 1 ATOM 6304 C CB . SER D 2 186 ? 5.404 -3.449 41.879 1.00 15.52 ? 186 SER D CB 1 ATOM 6305 O OG . SER D 2 186 ? 6.287 -4.435 41.386 1.00 15.13 ? 186 SER D OG 1 ATOM 6306 N N . VAL D 2 187 ? 4.818 -6.208 43.778 1.00 14.50 ? 187 VAL D N 1 ATOM 6307 C CA . VAL D 2 187 ? 5.395 -7.080 44.780 1.00 15.58 ? 187 VAL D CA 1 ATOM 6308 C C . VAL D 2 187 ? 6.296 -8.152 44.159 1.00 21.28 ? 187 VAL D C 1 ATOM 6309 O O . VAL D 2 187 ? 6.283 -8.409 42.946 1.00 19.50 ? 187 VAL D O 1 ATOM 6310 C CB . VAL D 2 187 ? 4.296 -7.771 45.599 1.00 15.38 ? 187 VAL D CB 1 ATOM 6311 C CG1 . VAL D 2 187 ? 3.488 -6.731 46.362 1.00 12.59 ? 187 VAL D CG1 1 ATOM 6312 C CG2 . VAL D 2 187 ? 3.397 -8.604 44.680 1.00 15.43 ? 187 VAL D CG2 1 ATOM 6313 N N . VAL D 2 188 ? 7.075 -8.783 45.011 1.00 15.46 ? 188 VAL D N 1 ATOM 6314 C CA . VAL D 2 188 ? 7.952 -9.845 44.587 1.00 16.69 ? 188 VAL D CA 1 ATOM 6315 C C . VAL D 2 188 ? 8.077 -10.752 45.797 1.00 16.71 ? 188 VAL D C 1 ATOM 6316 O O . VAL D 2 188 ? 7.981 -10.302 46.951 1.00 14.50 ? 188 VAL D O 1 ATOM 6317 C CB . VAL D 2 188 ? 9.347 -9.290 44.128 1.00 23.83 ? 188 VAL D CB 1 ATOM 6318 C CG1 . VAL D 2 188 ? 10.039 -8.512 45.256 1.00 13.55 ? 188 VAL D CG1 1 ATOM 6319 C CG2 . VAL D 2 188 ? 10.245 -10.398 43.583 1.00 14.87 ? 188 VAL D CG2 1 ATOM 6320 N N . THR D 2 189 ? 8.249 -12.037 45.543 1.00 14.74 ? 189 THR D N 1 ATOM 6321 C CA . THR D 2 189 ? 8.484 -12.960 46.629 1.00 13.72 ? 189 THR D CA 1 ATOM 6322 C C . THR D 2 189 ? 9.938 -13.380 46.606 1.00 22.63 ? 189 THR D C 1 ATOM 6323 O O . THR D 2 189 ? 10.531 -13.593 45.534 1.00 22.58 ? 189 THR D O 1 ATOM 6324 C CB . THR D 2 189 ? 7.549 -14.163 46.559 1.00 13.50 ? 189 THR D CB 1 ATOM 6325 O OG1 . THR D 2 189 ? 7.577 -14.719 45.235 1.00 16.73 ? 189 THR D OG1 1 ATOM 6326 C CG2 . THR D 2 189 ? 6.136 -13.701 46.879 1.00 14.25 ? 189 THR D CG2 1 ATOM 6327 N N . VAL D 2 190 ? 10.527 -13.446 47.797 1.00 21.51 ? 190 VAL D N 1 ATOM 6328 C CA . VAL D 2 190 ? 11.944 -13.756 47.938 1.00 16.39 ? 190 VAL D CA 1 ATOM 6329 C C . VAL D 2 190 ? 12.195 -14.703 49.112 1.00 17.66 ? 190 VAL D C 1 ATOM 6330 O O . VAL D 2 190 ? 11.392 -14.774 50.045 1.00 17.77 ? 190 VAL D O 1 ATOM 6331 C CB . VAL D 2 190 ? 12.793 -12.466 48.117 1.00 12.56 ? 190 VAL D CB 1 ATOM 6332 C CG1 . VAL D 2 190 ? 12.590 -11.524 46.952 1.00 17.94 ? 190 VAL D CG1 1 ATOM 6333 C CG2 . VAL D 2 190 ? 12.487 -11.789 49.416 1.00 11.66 ? 190 VAL D CG2 1 ATOM 6334 N N . PRO D 2 191 ? 13.323 -15.428 49.081 1.00 17.05 ? 191 PRO D N 1 ATOM 6335 C CA . PRO D 2 191 ? 13.666 -16.237 50.259 1.00 17.89 ? 191 PRO D CA 1 ATOM 6336 C C . PRO D 2 191 ? 13.848 -15.331 51.458 1.00 24.23 ? 191 PRO D C 1 ATOM 6337 O O . PRO D 2 191 ? 14.625 -14.380 51.366 1.00 25.38 ? 191 PRO D O 1 ATOM 6338 C CB . PRO D 2 191 ? 15.001 -16.857 49.879 1.00 12.00 ? 191 PRO D CB 1 ATOM 6339 C CG . PRO D 2 191 ? 15.014 -16.814 48.353 1.00 20.74 ? 191 PRO D CG 1 ATOM 6340 C CD . PRO D 2 191 ? 14.317 -15.554 48.002 1.00 9.29 ? 191 PRO D CD 1 ATOM 6341 N N . SER D 2 192 ? 13.148 -15.598 52.555 1.00 19.44 ? 192 SER D N 1 ATOM 6342 C CA . SER D 2 192 ? 13.197 -14.665 53.669 1.00 22.27 ? 192 SER D CA 1 ATOM 6343 C C . SER D 2 192 ? 14.598 -14.532 54.258 1.00 22.41 ? 192 SER D C 1 ATOM 6344 O O . SER D 2 192 ? 14.905 -13.516 54.875 1.00 23.48 ? 192 SER D O 1 ATOM 6345 C CB . SER D 2 192 ? 12.159 -14.993 54.747 1.00 17.33 ? 192 SER D CB 1 ATOM 6346 O OG . SER D 2 192 ? 12.383 -16.269 55.294 1.00 31.51 ? 192 SER D OG 1 ATOM 6347 N N . SER D 2 193 ? 15.455 -15.531 54.048 1.00 17.52 ? 193 SER D N 1 ATOM 6348 C CA . SER D 2 193 ? 16.819 -15.463 54.592 1.00 21.80 ? 193 SER D CA 1 ATOM 6349 C C . SER D 2 193 ? 17.768 -14.578 53.772 1.00 22.56 ? 193 SER D C 1 ATOM 6350 O O . SER D 2 193 ? 18.922 -14.384 54.138 1.00 28.25 ? 193 SER D O 1 ATOM 6351 C CB . SER D 2 193 ? 17.429 -16.850 54.812 1.00 19.66 ? 193 SER D CB 1 ATOM 6352 O OG . SER D 2 193 ? 17.525 -17.568 53.601 1.00 27.32 ? 193 SER D OG 1 ATOM 6353 N N . SER D 2 194 ? 17.275 -14.032 52.670 1.00 20.79 ? 194 SER D N 1 ATOM 6354 C CA . SER D 2 194 ? 18.067 -13.089 51.898 1.00 26.09 ? 194 SER D CA 1 ATOM 6355 C C . SER D 2 194 ? 17.746 -11.619 52.244 1.00 23.96 ? 194 SER D C 1 ATOM 6356 O O . SER D 2 194 ? 18.392 -10.702 51.747 1.00 28.80 ? 194 SER D O 1 ATOM 6357 C CB . SER D 2 194 ? 17.890 -13.358 50.400 1.00 20.59 ? 194 SER D CB 1 ATOM 6358 O OG . SER D 2 194 ? 16.558 -13.081 49.994 1.00 22.65 ? 194 SER D OG 1 ATOM 6359 N N . LEU D 2 195 ? 16.759 -11.403 53.104 1.00 23.11 ? 195 LEU D N 1 ATOM 6360 C CA . LEU D 2 195 ? 16.342 -10.051 53.459 1.00 28.32 ? 195 LEU D CA 1 ATOM 6361 C C . LEU D 2 195 ? 17.427 -9.221 54.127 1.00 31.37 ? 195 LEU D C 1 ATOM 6362 O O . LEU D 2 195 ? 17.391 -7.990 54.083 1.00 33.61 ? 195 LEU D O 1 ATOM 6363 C CB . LEU D 2 195 ? 15.119 -10.087 54.360 1.00 24.02 ? 195 LEU D CB 1 ATOM 6364 C CG . LEU D 2 195 ? 13.877 -10.597 53.652 1.00 25.40 ? 195 LEU D CG 1 ATOM 6365 C CD1 . LEU D 2 195 ? 12.662 -10.310 54.512 1.00 22.90 ? 195 LEU D CD1 1 ATOM 6366 C CD2 . LEU D 2 195 ? 13.767 -9.950 52.274 1.00 21.25 ? 195 LEU D CD2 1 ATOM 6367 N N . GLY D 2 196 ? 18.390 -9.895 54.744 1.00 37.33 ? 196 GLY D N 1 ATOM 6368 C CA . GLY D 2 196 ? 19.442 -9.214 55.471 1.00 30.74 ? 196 GLY D CA 1 ATOM 6369 C C . GLY D 2 196 ? 20.611 -8.836 54.590 1.00 31.28 ? 196 GLY D C 1 ATOM 6370 O O . GLY D 2 196 ? 21.148 -7.739 54.707 1.00 44.84 ? 196 GLY D O 1 ATOM 6371 N N . THR D 2 197 ? 20.992 -9.737 53.695 1.00 28.97 ? 197 THR D N 1 ATOM 6372 C CA . THR D 2 197 ? 22.206 -9.572 52.896 1.00 31.62 ? 197 THR D CA 1 ATOM 6373 C C . THR D 2 197 ? 21.987 -9.040 51.486 1.00 33.80 ? 197 THR D C 1 ATOM 6374 O O . THR D 2 197 ? 22.906 -8.476 50.891 1.00 31.82 ? 197 THR D O 1 ATOM 6375 C CB . THR D 2 197 ? 22.941 -10.909 52.760 1.00 41.26 ? 197 THR D CB 1 ATOM 6376 O OG1 . THR D 2 197 ? 21.989 -11.927 52.421 1.00 37.17 ? 197 THR D OG1 1 ATOM 6377 C CG2 . THR D 2 197 ? 23.647 -11.270 54.069 1.00 39.24 ? 197 THR D CG2 1 ATOM 6378 N N . GLN D 2 198 ? 20.787 -9.239 50.946 1.00 29.41 ? 198 GLN D N 1 ATOM 6379 C CA . GLN D 2 198 ? 20.496 -8.835 49.571 1.00 31.25 ? 198 GLN D CA 1 ATOM 6380 C C . GLN D 2 198 ? 19.556 -7.639 49.525 1.00 29.41 ? 198 GLN D C 1 ATOM 6381 O O . GLN D 2 198 ? 18.510 -7.650 50.172 1.00 28.09 ? 198 GLN D O 1 ATOM 6382 C CB . GLN D 2 198 ? 19.859 -9.989 48.806 1.00 31.46 ? 198 GLN D CB 1 ATOM 6383 C CG . GLN D 2 198 ? 19.351 -9.595 47.449 1.00 29.86 ? 198 GLN D CG 1 ATOM 6384 C CD . GLN D 2 198 ? 20.465 -9.476 46.437 1.00 33.70 ? 198 GLN D CD 1 ATOM 6385 O OE1 . GLN D 2 198 ? 21.330 -10.346 46.349 1.00 43.04 ? 198 GLN D OE1 1 ATOM 6386 N NE2 . GLN D 2 198 ? 20.453 -8.399 45.665 1.00 31.65 ? 198 GLN D NE2 1 ATOM 6387 N N . THR D 2 199 ? 19.911 -6.613 48.760 1.00 24.59 ? 199 THR D N 1 ATOM 6388 C CA . THR D 2 199 ? 19.057 -5.437 48.711 1.00 32.83 ? 199 THR D CA 1 ATOM 6389 C C . THR D 2 199 ? 17.994 -5.575 47.631 1.00 26.01 ? 199 THR D C 1 ATOM 6390 O O . THR D 2 199 ? 18.240 -6.150 46.570 1.00 24.73 ? 199 THR D O 1 ATOM 6391 C CB . THR D 2 199 ? 19.837 -4.123 48.529 1.00 25.78 ? 199 THR D CB 1 ATOM 6392 O OG1 . THR D 2 199 ? 20.249 -3.995 47.171 1.00 33.55 ? 199 THR D OG1 1 ATOM 6393 C CG2 . THR D 2 199 ? 21.051 -4.097 49.418 1.00 32.33 ? 199 THR D CG2 1 ATOM 6394 N N . TYR D 2 200 ? 16.803 -5.062 47.939 1.00 26.14 ? 200 TYR D N 1 ATOM 6395 C CA . TYR D 2 200 ? 15.667 -5.098 47.024 1.00 22.51 ? 200 TYR D CA 1 ATOM 6396 C C . TYR D 2 200 ? 15.174 -3.691 46.785 1.00 21.75 ? 200 TYR D C 1 ATOM 6397 O O . TYR D 2 200 ? 14.686 -3.012 47.689 1.00 30.55 ? 200 TYR D O 1 ATOM 6398 C CB . TYR D 2 200 ? 14.552 -5.971 47.586 1.00 19.89 ? 200 TYR D CB 1 ATOM 6399 C CG . TYR D 2 200 ? 14.975 -7.415 47.659 1.00 24.60 ? 200 TYR D CG 1 ATOM 6400 C CD1 . TYR D 2 200 ? 15.000 -8.200 46.512 1.00 26.01 ? 200 TYR D CD1 1 ATOM 6401 C CD2 . TYR D 2 200 ? 15.370 -7.991 48.859 1.00 18.61 ? 200 TYR D CD2 1 ATOM 6402 C CE1 . TYR D 2 200 ? 15.397 -9.514 46.555 1.00 23.77 ? 200 TYR D CE1 1 ATOM 6403 C CE2 . TYR D 2 200 ? 15.774 -9.310 48.909 1.00 19.43 ? 200 TYR D CE2 1 ATOM 6404 C CZ . TYR D 2 200 ? 15.786 -10.067 47.752 1.00 21.20 ? 200 TYR D CZ 1 ATOM 6405 O OH . TYR D 2 200 ? 16.186 -11.382 47.769 1.00 15.35 ? 200 TYR D OH 1 ATOM 6406 N N . ILE D 2 201 ? 15.333 -3.233 45.561 1.00 22.23 ? 201 ILE D N 1 ATOM 6407 C CA . ILE D 2 201 ? 14.929 -1.888 45.225 1.00 21.54 ? 201 ILE D CA 1 ATOM 6408 C C . ILE D 2 201 ? 13.851 -1.915 44.167 1.00 21.48 ? 201 ILE D C 1 ATOM 6409 O O . ILE D 2 201 ? 13.991 -2.588 43.154 1.00 21.32 ? 201 ILE D O 1 ATOM 6410 C CB . ILE D 2 201 ? 16.130 -1.108 44.691 1.00 21.91 ? 201 ILE D CB 1 ATOM 6411 C CG1 . ILE D 2 201 ? 17.240 -1.108 45.743 1.00 25.15 ? 201 ILE D CG1 1 ATOM 6412 C CG2 . ILE D 2 201 ? 15.725 0.304 44.280 1.00 17.75 ? 201 ILE D CG2 1 ATOM 6413 C CD1 . ILE D 2 201 ? 18.475 -0.410 45.284 1.00 40.53 ? 201 ILE D CD1 1 ATOM 6414 N N . CYS D 2 202 ? 12.764 -1.193 44.387 1.00 20.90 ? 202 CYS D N 1 ATOM 6415 C CA . CYS D 2 202 ? 11.858 -0.989 43.276 1.00 22.65 ? 202 CYS D CA 1 ATOM 6416 C C . CYS D 2 202 ? 12.200 0.322 42.585 1.00 17.99 ? 202 CYS D C 1 ATOM 6417 O O . CYS D 2 202 ? 12.466 1.339 43.229 1.00 19.17 ? 202 CYS D O 1 ATOM 6418 C CB . CYS D 2 202 ? 10.382 -1.052 43.686 1.00 25.31 ? 202 CYS D CB 1 ATOM 6419 S SG . CYS D 2 202 ? 9.786 0.418 44.514 1.00 34.04 ? 202 CYS D SG 1 ATOM 6420 N N . ASN D 2 203 ? 12.201 0.269 41.263 1.00 14.71 ? 203 ASN D N 1 ATOM 6421 C CA . ASN D 2 203 ? 12.560 1.399 40.437 1.00 17.18 ? 203 ASN D CA 1 ATOM 6422 C C . ASN D 2 203 ? 11.305 1.958 39.814 1.00 21.87 ? 203 ASN D C 1 ATOM 6423 O O . ASN D 2 203 ? 10.771 1.407 38.850 1.00 20.14 ? 203 ASN D O 1 ATOM 6424 C CB . ASN D 2 203 ? 13.540 0.960 39.348 1.00 18.82 ? 203 ASN D CB 1 ATOM 6425 C CG . ASN D 2 203 ? 14.716 0.182 39.910 1.00 20.72 ? 203 ASN D CG 1 ATOM 6426 O OD1 . ASN D 2 203 ? 14.876 -1.007 39.642 1.00 18.94 ? 203 ASN D OD1 1 ATOM 6427 N ND2 . ASN D 2 203 ? 15.539 0.852 40.709 1.00 20.54 ? 203 ASN D ND2 1 ATOM 6428 N N . VAL D 2 204 ? 10.827 3.053 40.380 1.00 23.41 ? 204 VAL D N 1 ATOM 6429 C CA . VAL D 2 204 ? 9.592 3.640 39.916 1.00 21.13 ? 204 VAL D CA 1 ATOM 6430 C C . VAL D 2 204 ? 9.888 4.817 39.033 1.00 19.02 ? 204 VAL D C 1 ATOM 6431 O O . VAL D 2 204 ? 10.683 5.674 39.386 1.00 20.11 ? 204 VAL D O 1 ATOM 6432 C CB . VAL D 2 204 ? 8.756 4.118 41.089 1.00 18.64 ? 204 VAL D CB 1 ATOM 6433 C CG1 . VAL D 2 204 ? 7.455 4.733 40.587 1.00 10.29 ? 204 VAL D CG1 1 ATOM 6434 C CG2 . VAL D 2 204 ? 8.525 2.958 42.051 1.00 15.10 ? 204 VAL D CG2 1 ATOM 6435 N N . ASN D 2 205 ? 9.247 4.844 37.873 1.00 28.17 ? 205 ASN D N 1 ATOM 6436 C CA . ASN D 2 205 ? 9.382 5.951 36.948 1.00 25.20 ? 205 ASN D CA 1 ATOM 6437 C C . ASN D 2 205 ? 8.018 6.362 36.423 1.00 22.78 ? 205 ASN D C 1 ATOM 6438 O O . ASN D 2 205 ? 7.329 5.583 35.759 1.00 25.93 ? 205 ASN D O 1 ATOM 6439 C CB . ASN D 2 205 ? 10.298 5.572 35.782 1.00 23.21 ? 205 ASN D CB 1 ATOM 6440 C CG . ASN D 2 205 ? 10.611 6.753 34.872 1.00 29.65 ? 205 ASN D CG 1 ATOM 6441 O OD1 . ASN D 2 205 ? 10.006 7.821 34.976 1.00 26.28 ? 205 ASN D OD1 1 ATOM 6442 N ND2 . ASN D 2 205 ? 11.557 6.556 33.968 1.00 25.36 ? 205 ASN D ND2 1 ATOM 6443 N N . HIS D 2 206 ? 7.636 7.592 36.733 1.00 22.17 ? 206 HIS D N 1 ATOM 6444 C CA . HIS D 2 206 ? 6.428 8.178 36.187 1.00 18.82 ? 206 HIS D CA 1 ATOM 6445 C C . HIS D 2 206 ? 6.850 9.195 35.147 1.00 20.15 ? 206 HIS D C 1 ATOM 6446 O O . HIS D 2 206 ? 7.106 10.347 35.479 1.00 24.32 ? 206 HIS D O 1 ATOM 6447 C CB . HIS D 2 206 ? 5.635 8.882 37.290 1.00 20.63 ? 206 HIS D CB 1 ATOM 6448 C CG . HIS D 2 206 ? 4.304 9.398 36.839 1.00 18.60 ? 206 HIS D CG 1 ATOM 6449 N ND1 . HIS D 2 206 ? 3.968 10.732 36.900 1.00 18.84 ? 206 HIS D ND1 1 ATOM 6450 C CD2 . HIS D 2 206 ? 3.232 8.760 36.321 1.00 15.39 ? 206 HIS D CD2 1 ATOM 6451 C CE1 . HIS D 2 206 ? 2.742 10.892 36.434 1.00 16.51 ? 206 HIS D CE1 1 ATOM 6452 N NE2 . HIS D 2 206 ? 2.273 9.713 36.075 1.00 13.94 ? 206 HIS D NE2 1 ATOM 6453 N N . LYS D 2 207 ? 6.933 8.777 33.890 1.00 24.21 ? 207 LYS D N 1 ATOM 6454 C CA . LYS D 2 207 ? 7.404 9.669 32.820 1.00 22.04 ? 207 LYS D CA 1 ATOM 6455 C C . LYS D 2 207 ? 6.590 10.946 32.552 1.00 25.31 ? 207 LYS D C 1 ATOM 6456 O O . LYS D 2 207 ? 7.182 11.981 32.262 1.00 34.71 ? 207 LYS D O 1 ATOM 6457 C CB . LYS D 2 207 ? 7.658 8.898 31.519 1.00 21.75 ? 207 LYS D CB 1 ATOM 6458 C CG . LYS D 2 207 ? 8.933 8.080 31.542 1.00 22.99 ? 207 LYS D CG 1 ATOM 6459 C CD . LYS D 2 207 ? 8.932 7.010 30.472 1.00 31.54 ? 207 LYS D CD 1 ATOM 6460 C CE . LYS D 2 207 ? 10.229 6.212 30.495 1.00 33.51 ? 207 LYS D CE 1 ATOM 6461 N NZ . LYS D 2 207 ? 10.300 5.249 29.354 1.00 37.62 ? 207 LYS D NZ 1 ATOM 6462 N N . PRO D 2 208 ? 5.244 10.887 32.638 1.00 23.10 ? 208 PRO D N 1 ATOM 6463 C CA . PRO D 2 208 ? 4.494 12.131 32.425 1.00 23.76 ? 208 PRO D CA 1 ATOM 6464 C C . PRO D 2 208 ? 4.864 13.269 33.382 1.00 26.14 ? 208 PRO D C 1 ATOM 6465 O O . PRO D 2 208 ? 4.662 14.435 33.041 1.00 24.85 ? 208 PRO D O 1 ATOM 6466 C CB . PRO D 2 208 ? 3.049 11.704 32.666 1.00 21.14 ? 208 PRO D CB 1 ATOM 6467 C CG . PRO D 2 208 ? 3.029 10.289 32.336 1.00 21.45 ? 208 PRO D CG 1 ATOM 6468 C CD . PRO D 2 208 ? 4.340 9.727 32.728 1.00 15.11 ? 208 PRO D CD 1 ATOM 6469 N N . SER D 2 209 ? 5.405 12.948 34.552 1.00 21.70 ? 209 SER D N 1 ATOM 6470 C CA . SER D 2 209 ? 5.782 13.996 35.498 1.00 21.98 ? 209 SER D CA 1 ATOM 6471 C C . SER D 2 209 ? 7.295 14.030 35.715 1.00 29.43 ? 209 SER D C 1 ATOM 6472 O O . SER D 2 209 ? 7.782 14.696 36.634 1.00 23.81 ? 209 SER D O 1 ATOM 6473 C CB . SER D 2 209 ? 5.089 13.781 36.842 1.00 20.43 ? 209 SER D CB 1 ATOM 6474 O OG . SER D 2 209 ? 5.746 12.764 37.583 1.00 25.64 ? 209 SER D OG 1 ATOM 6475 N N . ASN D 2 210 ? 8.033 13.299 34.886 1.00 22.24 ? 210 ASN D N 1 ATOM 6476 C CA . ASN D 2 210 ? 9.480 13.146 35.094 1.00 30.37 ? 210 ASN D CA 1 ATOM 6477 C C . ASN D 2 210 ? 9.932 12.737 36.518 1.00 25.68 ? 210 ASN D C 1 ATOM 6478 O O . ASN D 2 210 ? 11.057 13.026 36.920 1.00 37.12 ? 210 ASN D O 1 ATOM 6479 C CB . ASN D 2 210 ? 10.219 14.413 34.633 1.00 31.02 ? 210 ASN D CB 1 ATOM 6480 C CG . ASN D 2 210 ? 9.946 14.748 33.165 1.00 43.12 ? 210 ASN D CG 1 ATOM 6481 O OD1 . ASN D 2 210 ? 10.053 13.889 32.285 1.00 29.75 ? 210 ASN D OD1 1 ATOM 6482 N ND2 . ASN D 2 210 ? 9.578 15.996 32.901 1.00 38.27 ? 210 ASN D ND2 1 ATOM 6483 N N . THR D 2 211 ? 9.067 12.063 37.274 1.00 22.50 ? 211 THR D N 1 ATOM 6484 C CA . THR D 2 211 ? 9.429 11.596 38.616 1.00 17.86 ? 211 THR D CA 1 ATOM 6485 C C . THR D 2 211 ? 10.015 10.196 38.590 1.00 19.12 ? 211 THR D C 1 ATOM 6486 O O . THR D 2 211 ? 9.375 9.255 38.123 1.00 22.76 ? 211 THR D O 1 ATOM 6487 C CB . THR D 2 211 ? 8.219 11.587 39.559 1.00 20.15 ? 211 THR D CB 1 ATOM 6488 O OG1 . THR D 2 211 ? 7.661 12.904 39.624 1.00 24.61 ? 211 THR D OG1 1 ATOM 6489 C CG2 . THR D 2 211 ? 8.623 11.119 40.973 1.00 16.50 ? 211 THR D CG2 1 ATOM 6490 N N . LYS D 2 212 ? 11.242 10.066 39.083 1.00 23.47 ? 212 LYS D N 1 ATOM 6491 C CA . LYS D 2 212 ? 11.894 8.765 39.231 1.00 20.10 ? 212 LYS D CA 1 ATOM 6492 C C . LYS D 2 212 ? 12.294 8.513 40.693 1.00 20.93 ? 212 LYS D C 1 ATOM 6493 O O . LYS D 2 212 ? 12.919 9.357 41.343 1.00 16.32 ? 212 LYS D O 1 ATOM 6494 C CB . LYS D 2 212 ? 13.125 8.649 38.327 1.00 19.39 ? 212 LYS D CB 1 ATOM 6495 C CG . LYS D 2 212 ? 12.805 8.674 36.837 1.00 35.31 ? 212 LYS D CG 1 ATOM 6496 C CD . LYS D 2 212 ? 13.995 8.216 35.986 1.00 30.77 ? 212 LYS D CD 1 ATOM 6497 C CE . LYS D 2 212 ? 15.192 9.121 36.192 1.00 39.18 ? 212 LYS D CE 1 ATOM 6498 N NZ . LYS D 2 212 ? 16.468 8.529 35.665 1.00 39.14 ? 212 LYS D NZ 1 ATOM 6499 N N . VAL D 2 213 ? 11.923 7.343 41.204 1.00 19.37 ? 213 VAL D N 1 ATOM 6500 C CA . VAL D 2 213 ? 12.242 6.970 42.562 1.00 17.51 ? 213 VAL D CA 1 ATOM 6501 C C . VAL D 2 213 ? 12.801 5.561 42.621 1.00 22.05 ? 213 VAL D C 1 ATOM 6502 O O . VAL D 2 213 ? 12.221 4.634 42.062 1.00 24.29 ? 213 VAL D O 1 ATOM 6503 C CB . VAL D 2 213 ? 11.005 7.058 43.486 1.00 22.32 ? 213 VAL D CB 1 ATOM 6504 C CG1 . VAL D 2 213 ? 11.354 6.597 44.919 1.00 13.58 ? 213 VAL D CG1 1 ATOM 6505 C CG2 . VAL D 2 213 ? 10.461 8.469 43.510 1.00 13.27 ? 213 VAL D CG2 1 ATOM 6506 N N . ASP D 2 214 ? 13.937 5.412 43.296 1.00 20.31 ? 214 ASP D N 1 ATOM 6507 C CA . ASP D 2 214 ? 14.469 4.102 43.626 1.00 18.87 ? 214 ASP D CA 1 ATOM 6508 C C . ASP D 2 214 ? 14.206 3.896 45.108 1.00 24.38 ? 214 ASP D C 1 ATOM 6509 O O . ASP D 2 214 ? 14.677 4.671 45.942 1.00 22.76 ? 214 ASP D O 1 ATOM 6510 C CB . ASP D 2 214 ? 15.968 4.032 43.361 1.00 19.72 ? 214 ASP D CB 1 ATOM 6511 C CG . ASP D 2 214 ? 16.312 4.125 41.879 1.00 30.95 ? 214 ASP D CG 1 ATOM 6512 O OD1 . ASP D 2 214 ? 15.519 3.629 41.041 1.00 22.90 ? 214 ASP D OD1 1 ATOM 6513 O OD2 . ASP D 2 214 ? 17.385 4.689 41.553 1.00 28.16 ? 214 ASP D OD2 1 ATOM 6514 N N . LYS D 2 215 ? 13.448 2.856 45.442 1.00 20.83 ? 215 LYS D N 1 ATOM 6515 C CA . LYS D 2 215 ? 13.050 2.631 46.824 1.00 22.67 ? 215 LYS D CA 1 ATOM 6516 C C . LYS D 2 215 ? 13.528 1.281 47.304 1.00 21.86 ? 215 LYS D C 1 ATOM 6517 O O . LYS D 2 215 ? 13.232 0.261 46.684 1.00 22.16 ? 215 LYS D O 1 ATOM 6518 C CB . LYS D 2 215 ? 11.527 2.727 46.980 1.00 14.43 ? 215 LYS D CB 1 ATOM 6519 C CG . LYS D 2 215 ? 11.044 2.465 48.420 1.00 20.23 ? 215 LYS D CG 1 ATOM 6520 C CD . LYS D 2 215 ? 11.289 3.661 49.347 1.00 19.95 ? 215 LYS D CD 1 ATOM 6521 C CE . LYS D 2 215 ? 11.018 3.324 50.805 1.00 21.58 ? 215 LYS D CE 1 ATOM 6522 N NZ . LYS D 2 215 ? 11.057 4.515 51.714 1.00 25.20 ? 215 LYS D NZ 1 ATOM 6523 N N . ARG D 2 216 ? 14.264 1.280 48.413 1.00 24.05 ? 216 ARG D N 1 ATOM 6524 C CA . ARG D 2 216 ? 14.687 0.035 49.032 1.00 24.23 ? 216 ARG D CA 1 ATOM 6525 C C . ARG D 2 216 ? 13.578 -0.427 49.958 1.00 21.08 ? 216 ARG D C 1 ATOM 6526 O O . ARG D 2 216 ? 12.954 0.390 50.632 1.00 21.42 ? 216 ARG D O 1 ATOM 6527 C CB . ARG D 2 216 ? 15.982 0.215 49.827 1.00 24.46 ? 216 ARG D CB 1 ATOM 6528 C CG . ARG D 2 216 ? 16.333 -1.048 50.594 1.00 23.56 ? 216 ARG D CG 1 ATOM 6529 C CD . ARG D 2 216 ? 17.709 -1.078 51.201 1.00 26.39 ? 216 ARG D CD 1 ATOM 6530 N NE . ARG D 2 216 ? 17.973 -2.440 51.668 1.00 36.66 ? 216 ARG D NE 1 ATOM 6531 C CZ . ARG D 2 216 ? 18.675 -2.743 52.757 1.00 31.85 ? 216 ARG D CZ 1 ATOM 6532 N NH1 . ARG D 2 216 ? 19.197 -1.781 53.503 1.00 36.18 ? 216 ARG D NH1 1 ATOM 6533 N NH2 . ARG D 2 216 ? 18.852 -4.011 53.101 1.00 34.48 ? 216 ARG D NH2 1 ATOM 6534 N N . VAL D 2 217 ? 13.322 -1.731 49.982 1.00 21.59 ? 217 VAL D N 1 ATOM 6535 C CA . VAL D 2 217 ? 12.248 -2.276 50.800 1.00 18.89 ? 217 VAL D CA 1 ATOM 6536 C C . VAL D 2 217 ? 12.822 -3.382 51.667 1.00 18.56 ? 217 VAL D C 1 ATOM 6537 O O . VAL D 2 217 ? 13.413 -4.333 51.162 1.00 22.14 ? 217 VAL D O 1 ATOM 6538 C CB . VAL D 2 217 ? 11.086 -2.832 49.932 1.00 17.83 ? 217 VAL D CB 1 ATOM 6539 C CG1 . VAL D 2 217 ? 9.966 -3.340 50.815 1.00 23.23 ? 217 VAL D CG1 1 ATOM 6540 C CG2 . VAL D 2 217 ? 10.565 -1.763 48.985 1.00 14.16 ? 217 VAL D CG2 1 ATOM 6541 N N . GLU D 2 218 ? 12.679 -3.235 52.975 1.00 23.40 ? 218 GLU D N 1 ATOM 6542 C CA . GLU D 2 218 ? 13.240 -4.186 53.929 1.00 28.19 ? 218 GLU D CA 1 ATOM 6543 C C . GLU D 2 218 ? 12.325 -4.228 55.135 1.00 28.57 ? 218 GLU D C 1 ATOM 6544 O O . GLU D 2 218 ? 11.512 -3.314 55.309 1.00 28.84 ? 218 GLU D O 1 ATOM 6545 C CB . GLU D 2 218 ? 14.631 -3.745 54.351 1.00 16.61 ? 218 GLU D CB 1 ATOM 6546 C CG . GLU D 2 218 ? 14.669 -2.350 54.881 1.00 26.33 ? 218 GLU D CG 1 ATOM 6547 C CD . GLU D 2 218 ? 16.064 -1.955 55.314 1.00 41.16 ? 218 GLU D CD 1 ATOM 6548 O OE1 . GLU D 2 218 ? 16.401 -0.751 55.235 1.00 44.04 ? 218 GLU D OE1 1 ATOM 6549 O OE2 . GLU D 2 218 ? 16.826 -2.857 55.728 1.00 48.58 ? 218 GLU D OE2 1 ATOM 6550 N N . PRO D 2 219 ? 12.434 -5.284 55.967 1.00 31.11 ? 219 PRO D N 1 ATOM 6551 C CA . PRO D 2 219 ? 11.536 -5.371 57.130 1.00 33.99 ? 219 PRO D CA 1 ATOM 6552 C C . PRO D 2 219 ? 11.801 -4.245 58.112 1.00 25.52 ? 219 PRO D C 1 ATOM 6553 O O . PRO D 2 219 ? 12.961 -3.936 58.358 1.00 24.02 ? 219 PRO D O 1 ATOM 6554 C CB . PRO D 2 219 ? 11.890 -6.723 57.753 1.00 34.49 ? 219 PRO D CB 1 ATOM 6555 C CG . PRO D 2 219 ? 13.251 -7.051 57.229 1.00 26.37 ? 219 PRO D CG 1 ATOM 6556 C CD . PRO D 2 219 ? 13.315 -6.461 55.863 1.00 29.14 ? 219 PRO D CD 1 ATOM 6557 N N . LYS D 2 220 ? 10.737 -3.636 58.638 1.00 38.31 ? 220 LYS D N 1 ATOM 6558 C CA . LYS D 2 220 ? 10.854 -2.502 59.565 1.00 41.01 ? 220 LYS D CA 1 ATOM 6559 C C . LYS D 2 220 ? 11.297 -2.925 60.975 1.00 33.33 ? 220 LYS D C 1 ATOM 6560 O O . LYS D 2 220 ? 11.557 -4.110 61.241 1.00 30.52 ? 220 LYS D O 1 ATOM 6561 C CB . LYS D 2 220 ? 9.537 -1.729 59.642 1.00 38.90 ? 220 LYS D CB 1 ATOM 6562 C CG . LYS D 2 220 ? 9.516 -0.620 60.696 1.00 57.09 ? 220 LYS D CG 1 ATOM 6563 C CD . LYS D 2 220 ? 8.101 -0.305 61.189 1.00 51.47 ? 220 LYS D CD 1 ATOM 6564 C CE . LYS D 2 220 ? 8.100 -0.044 62.701 1.00 61.09 ? 220 LYS D CE 1 ATOM 6565 N NZ . LYS D 2 220 ? 6.801 0.473 63.226 1.00 60.54 ? 220 LYS D NZ 1 ATOM 6566 N N . CYS E 3 1 ? -15.123 -32.687 26.701 1.00 59.54 ? 1 CYS E N 1 ATOM 6567 C CA . CYS E 3 1 ? -15.902 -32.797 27.935 1.00 59.70 ? 1 CYS E CA 1 ATOM 6568 C C . CYS E 3 1 ? -16.370 -34.228 28.206 1.00 62.72 ? 1 CYS E C 1 ATOM 6569 O O . CYS E 3 1 ? -15.836 -35.195 27.651 1.00 71.55 ? 1 CYS E O 1 ATOM 6570 C CB . CYS E 3 1 ? -17.121 -31.864 27.889 1.00 52.00 ? 1 CYS E CB 1 ATOM 6571 S SG . CYS E 3 1 ? -16.892 -30.189 28.597 1.00 59.99 ? 1 CYS E SG 1 ATOM 6572 N N . GLN E 3 2 ? -17.373 -34.349 29.072 1.00 55.88 ? 2 GLN E N 1 ATOM 6573 C CA . GLN E 3 2 ? -17.978 -35.635 29.403 1.00 46.82 ? 2 GLN E CA 1 ATOM 6574 C C . GLN E 3 2 ? -19.495 -35.531 29.356 1.00 38.79 ? 2 GLN E C 1 ATOM 6575 O O . GLN E 3 2 ? -20.066 -34.530 29.773 1.00 38.49 ? 2 GLN E O 1 ATOM 6576 C CB . GLN E 3 2 ? -17.520 -36.089 30.783 1.00 41.22 ? 2 GLN E CB 1 ATOM 6577 C CG . GLN E 3 2 ? -16.122 -36.673 30.786 1.00 57.97 ? 2 GLN E CG 1 ATOM 6578 C CD . GLN E 3 2 ? -16.067 -38.045 30.126 1.00 71.27 ? 2 GLN E CD 1 ATOM 6579 O OE1 . GLN E 3 2 ? -16.760 -38.977 30.551 1.00 65.75 ? 2 GLN E OE1 1 ATOM 6580 N NE2 . GLN E 3 2 ? -15.246 -38.174 29.077 1.00 56.84 ? 2 GLN E NE2 1 ATOM 6581 N N . HIS E 3 3 ? -20.149 -36.562 28.838 1.00 36.56 ? 3 HIS E N 1 ATOM 6582 C CA . HIS E 3 3 ? -21.603 -36.538 28.703 1.00 33.19 ? 3 HIS E CA 1 ATOM 6583 C C . HIS E 3 3 ? -22.275 -37.275 29.861 1.00 28.33 ? 3 HIS E C 1 ATOM 6584 O O . HIS E 3 3 ? -22.128 -38.488 30.002 1.00 32.39 ? 3 HIS E O 1 ATOM 6585 C CB . HIS E 3 3 ? -22.025 -37.112 27.348 1.00 27.79 ? 3 HIS E CB 1 ATOM 6586 C CG . HIS E 3 3 ? -21.269 -36.534 26.192 1.00 34.37 ? 3 HIS E CG 1 ATOM 6587 N ND1 . HIS E 3 3 ? -19.967 -36.882 25.905 1.00 32.78 ? 3 HIS E ND1 1 ATOM 6588 C CD2 . HIS E 3 3 ? -21.628 -35.622 25.259 1.00 34.79 ? 3 HIS E CD2 1 ATOM 6589 C CE1 . HIS E 3 3 ? -19.558 -36.213 24.843 1.00 32.67 ? 3 HIS E CE1 1 ATOM 6590 N NE2 . HIS E 3 3 ? -20.547 -35.441 24.431 1.00 27.59 ? 3 HIS E NE2 1 ATOM 6591 N N . ASP E 3 4 ? -23.003 -36.521 30.685 1.00 26.86 ? 4 ASP E N 1 ATOM 6592 C CA . ASP E 3 4 ? -23.611 -37.018 31.918 1.00 20.76 ? 4 ASP E CA 1 ATOM 6593 C C . ASP E 3 4 ? -25.002 -37.579 31.628 1.00 24.75 ? 4 ASP E C 1 ATOM 6594 O O . ASP E 3 4 ? -25.886 -36.845 31.198 1.00 25.77 ? 4 ASP E O 1 ATOM 6595 C CB . ASP E 3 4 ? -23.680 -35.867 32.932 1.00 30.94 ? 4 ASP E CB 1 ATOM 6596 C CG . ASP E 3 4 ? -24.202 -36.290 34.298 1.00 30.63 ? 4 ASP E CG 1 ATOM 6597 O OD1 . ASP E 3 4 ? -24.462 -37.487 34.514 1.00 34.68 ? 4 ASP E OD1 1 ATOM 6598 O OD2 . ASP E 3 4 ? -24.343 -35.401 35.164 1.00 38.83 ? 4 ASP E OD2 1 ATOM 6599 N N . LEU E 3 5 ? -25.190 -38.877 31.867 1.00 22.49 ? 5 LEU E N 1 ATOM 6600 C CA . LEU E 3 5 ? -26.429 -39.563 31.508 1.00 20.62 ? 5 LEU E CA 1 ATOM 6601 C C . LEU E 3 5 ? -27.579 -39.247 32.448 1.00 31.77 ? 5 LEU E C 1 ATOM 6602 O O . LEU E 3 5 ? -28.738 -39.502 32.112 1.00 33.96 ? 5 LEU E O 1 ATOM 6603 C CB . LEU E 3 5 ? -26.231 -41.074 31.456 1.00 18.12 ? 5 LEU E CB 1 ATOM 6604 C CG . LEU E 3 5 ? -25.148 -41.597 30.524 1.00 22.49 ? 5 LEU E CG 1 ATOM 6605 C CD1 . LEU E 3 5 ? -25.225 -43.105 30.450 1.00 25.18 ? 5 LEU E CD1 1 ATOM 6606 C CD2 . LEU E 3 5 ? -25.270 -40.982 29.143 1.00 29.11 ? 5 LEU E CD2 1 ATOM 6607 N N . SER E 3 6 ? -27.263 -38.710 33.626 1.00 27.73 ? 6 SER E N 1 ATOM 6608 C CA . SER E 3 6 ? -28.292 -38.296 34.577 1.00 32.39 ? 6 SER E CA 1 ATOM 6609 C C . SER E 3 6 ? -28.976 -37.009 34.121 1.00 28.59 ? 6 SER E C 1 ATOM 6610 O O . SER E 3 6 ? -30.198 -36.937 34.078 1.00 26.87 ? 6 SER E O 1 ATOM 6611 C CB . SER E 3 6 ? -27.696 -38.085 35.978 1.00 31.94 ? 6 SER E CB 1 ATOM 6612 O OG . SER E 3 6 ? -27.259 -39.298 36.551 1.00 26.65 ? 6 SER E OG 1 ATOM 6613 N N . THR E 3 7 ? -28.182 -35.992 33.798 1.00 29.31 ? 7 THR E N 1 ATOM 6614 C CA . THR E 3 7 ? -28.727 -34.682 33.439 1.00 28.63 ? 7 THR E CA 1 ATOM 6615 C C . THR E 3 7 ? -28.860 -34.499 31.934 1.00 31.66 ? 7 THR E C 1 ATOM 6616 O O . THR E 3 7 ? -29.532 -33.571 31.477 1.00 31.63 ? 7 THR E O 1 ATOM 6617 C CB . THR E 3 7 ? -27.865 -33.520 33.991 1.00 35.04 ? 7 THR E CB 1 ATOM 6618 O OG1 . THR E 3 7 ? -26.595 -33.481 33.315 1.00 35.25 ? 7 THR E OG1 1 ATOM 6619 C CG2 . THR E 3 7 ? -27.660 -33.674 35.500 1.00 34.79 ? 7 THR E CG2 1 ATOM 6620 N N . ARG E 3 8 ? -28.227 -35.387 31.175 1.00 18.90 ? 8 ARG E N 1 ATOM 6621 C CA . ARG E 3 8 ? -28.160 -35.251 29.728 1.00 29.52 ? 8 ARG E CA 1 ATOM 6622 C C . ARG E 3 8 ? -27.469 -33.953 29.339 1.00 25.57 ? 8 ARG E C 1 ATOM 6623 O O . ARG E 3 8 ? -27.777 -33.358 28.319 1.00 30.71 ? 8 ARG E O 1 ATOM 6624 C CB . ARG E 3 8 ? -29.554 -35.336 29.092 1.00 30.20 ? 8 ARG E CB 1 ATOM 6625 C CG . ARG E 3 8 ? -30.278 -36.616 29.400 1.00 21.59 ? 8 ARG E CG 1 ATOM 6626 C CD . ARG E 3 8 ? -31.417 -36.784 28.460 1.00 25.79 ? 8 ARG E CD 1 ATOM 6627 N NE . ARG E 3 8 ? -32.223 -37.950 28.791 1.00 30.48 ? 8 ARG E NE 1 ATOM 6628 C CZ . ARG E 3 8 ? -33.256 -38.377 28.071 1.00 26.75 ? 8 ARG E CZ 1 ATOM 6629 N NH1 . ARG E 3 8 ? -33.602 -37.737 26.957 1.00 22.94 ? 8 ARG E NH1 1 ATOM 6630 N NH2 . ARG E 3 8 ? -33.929 -39.453 28.464 1.00 25.33 ? 8 ARG E NH2 1 ATOM 6631 N N . ARG E 3 9 ? -26.530 -33.518 30.164 1.00 24.19 ? 9 ARG E N 1 ATOM 6632 C CA . ARG E 3 9 ? -25.803 -32.300 29.895 1.00 20.63 ? 9 ARG E CA 1 ATOM 6633 C C . ARG E 3 9 ? -24.311 -32.563 29.927 1.00 24.20 ? 9 ARG E C 1 ATOM 6634 O O . ARG E 3 9 ? -23.850 -33.514 30.563 1.00 25.82 ? 9 ARG E O 1 ATOM 6635 C CB . ARG E 3 9 ? -26.166 -31.241 30.929 1.00 21.71 ? 9 ARG E CB 1 ATOM 6636 C CG . ARG E 3 9 ? -27.580 -30.744 30.822 1.00 25.37 ? 9 ARG E CG 1 ATOM 6637 C CD . ARG E 3 9 ? -27.805 -29.978 29.534 1.00 23.20 ? 9 ARG E CD 1 ATOM 6638 N NE . ARG E 3 9 ? -26.824 -28.913 29.323 1.00 21.73 ? 9 ARG E NE 1 ATOM 6639 C CZ . ARG E 3 9 ? -26.783 -27.776 30.016 1.00 27.01 ? 9 ARG E CZ 1 ATOM 6640 N NH1 . ARG E 3 9 ? -27.651 -27.538 31.005 1.00 21.88 ? 9 ARG E NH1 1 ATOM 6641 N NH2 . ARG E 3 9 ? -25.859 -26.874 29.726 1.00 24.96 ? 9 ARG E NH2 1 ATOM 6642 N N . LEU E 3 10 ? -23.555 -31.725 29.232 1.00 24.86 ? 10 LEU E N 1 ATOM 6643 C CA . LEU E 3 10 ? -22.109 -31.811 29.290 1.00 24.68 ? 10 LEU E CA 1 ATOM 6644 C C . LEU E 3 10 ? -21.653 -31.458 30.687 1.00 25.16 ? 10 LEU E C 1 ATOM 6645 O O . LEU E 3 10 ? -22.236 -30.606 31.354 1.00 31.46 ? 10 LEU E O 1 ATOM 6646 C CB . LEU E 3 10 ? -21.452 -30.874 28.278 1.00 28.51 ? 10 LEU E CB 1 ATOM 6647 C CG . LEU E 3 10 ? -21.555 -31.178 26.785 1.00 28.74 ? 10 LEU E CG 1 ATOM 6648 C CD1 . LEU E 3 10 ? -20.792 -30.121 26.013 1.00 28.87 ? 10 LEU E CD1 1 ATOM 6649 C CD2 . LEU E 3 10 ? -21.021 -32.557 26.475 1.00 30.07 ? 10 LEU E CD2 1 ATOM 6650 N N . LYS E 3 11 ? -20.603 -32.127 31.124 1.00 28.56 ? 11 LYS E N 1 ATOM 6651 C CA . LYS E 3 11 ? -20.057 -31.921 32.447 1.00 32.81 ? 11 LYS E CA 1 ATOM 6652 C C . LYS E 3 11 ? -18.552 -31.781 32.293 1.00 39.63 ? 11 LYS E C 1 ATOM 6653 O O . LYS E 3 11 ? -17.901 -32.624 31.674 1.00 36.78 ? 11 LYS E O 1 ATOM 6654 C CB . LYS E 3 11 ? -20.393 -33.123 33.327 1.00 33.16 ? 11 LYS E CB 1 ATOM 6655 C CG . LYS E 3 11 ? -20.144 -32.952 34.816 1.00 39.45 ? 11 LYS E CG 1 ATOM 6656 C CD . LYS E 3 11 ? -20.558 -34.226 35.548 1.00 43.74 ? 11 LYS E CD 1 ATOM 6657 C CE . LYS E 3 11 ? -20.582 -34.043 37.058 1.00 55.13 ? 11 LYS E CE 1 ATOM 6658 N NZ . LYS E 3 11 ? -21.637 -33.088 37.493 1.00 54.67 ? 11 LYS E NZ 1 ATOM 6659 N N . CYS E 3 12 ? -18.002 -30.700 32.832 1.00 53.88 ? 12 CYS E N 1 ATOM 6660 C CA . CYS E 3 12 ? -16.568 -30.457 32.734 1.00 56.30 ? 12 CYS E CA 1 ATOM 6661 C C . CYS E 3 12 ? -15.930 -30.424 34.124 1.00 74.35 ? 12 CYS E C 1 ATOM 6662 O O . CYS E 3 12 ? -16.615 -30.271 35.143 1.00 79.99 ? 12 CYS E O 1 ATOM 6663 C CB . CYS E 3 12 ? -16.290 -29.162 31.955 1.00 49.21 ? 12 CYS E CB 1 ATOM 6664 S SG . CYS E 3 12 ? -17.082 -29.069 30.280 1.00 67.97 ? 12 CYS E SG 1 ATOM 6665 O OXT . CYS E 3 12 ? -14.713 -30.571 34.261 1.00 93.75 ? 12 CYS E OXT 1 ATOM 6666 N N . CYS F 3 1 ? -16.044 -7.413 24.865 1.00 63.57 ? 1 CYS F N 1 ATOM 6667 C CA . CYS F 3 1 ? -15.285 -7.037 26.058 1.00 62.58 ? 1 CYS F CA 1 ATOM 6668 C C . CYS F 3 1 ? -14.761 -5.600 26.002 1.00 64.66 ? 1 CYS F C 1 ATOM 6669 O O . CYS F 3 1 ? -15.103 -4.836 25.095 1.00 70.76 ? 1 CYS F O 1 ATOM 6670 C CB . CYS F 3 1 ? -14.114 -7.993 26.270 1.00 54.30 ? 1 CYS F CB 1 ATOM 6671 S SG . CYS F 3 1 ? -14.471 -9.399 27.328 1.00 70.82 ? 1 CYS F SG 1 ATOM 6672 N N . GLN F 3 2 ? -13.912 -5.247 26.966 1.00 58.02 ? 2 GLN F N 1 ATOM 6673 C CA . GLN F 3 2 ? -13.367 -3.894 27.061 1.00 50.84 ? 2 GLN F CA 1 ATOM 6674 C C . GLN F 3 2 ? -11.845 -3.843 26.926 1.00 50.26 ? 2 GLN F C 1 ATOM 6675 O O . GLN F 3 2 ? -11.135 -4.746 27.376 1.00 43.91 ? 2 GLN F O 1 ATOM 6676 C CB . GLN F 3 2 ? -13.764 -3.257 28.385 1.00 52.91 ? 2 GLN F CB 1 ATOM 6677 C CG . GLN F 3 2 ? -13.835 -1.752 28.327 1.00 52.54 ? 2 GLN F CG 1 ATOM 6678 C CD . GLN F 3 2 ? -15.047 -1.282 27.552 1.00 67.25 ? 2 GLN F CD 1 ATOM 6679 O OE1 . GLN F 3 2 ? -16.048 -1.997 27.456 1.00 72.22 ? 2 GLN F OE1 1 ATOM 6680 N NE2 . GLN F 3 2 ? -14.968 -0.077 26.995 1.00 54.24 ? 2 GLN F NE2 1 ATOM 6681 N N . HIS F 3 3 ? -11.352 -2.761 26.329 1.00 46.09 ? 3 HIS F N 1 ATOM 6682 C CA . HIS F 3 3 ? -9.929 -2.608 26.053 1.00 43.06 ? 3 HIS F CA 1 ATOM 6683 C C . HIS F 3 3 ? -9.233 -1.751 27.109 1.00 32.96 ? 3 HIS F C 1 ATOM 6684 O O . HIS F 3 3 ? -9.422 -0.542 27.162 1.00 32.93 ? 3 HIS F O 1 ATOM 6685 C CB . HIS F 3 3 ? -9.716 -2.016 24.655 1.00 43.61 ? 3 HIS F CB 1 ATOM 6686 C CG . HIS F 3 3 ? -10.256 -2.866 23.545 1.00 43.66 ? 3 HIS F CG 1 ATOM 6687 N ND1 . HIS F 3 3 ? -11.550 -2.752 23.080 1.00 47.30 ? 3 HIS F ND1 1 ATOM 6688 C CD2 . HIS F 3 3 ? -9.674 -3.840 22.806 1.00 43.20 ? 3 HIS F CD2 1 ATOM 6689 C CE1 . HIS F 3 3 ? -11.742 -3.625 22.106 1.00 46.38 ? 3 HIS F CE1 1 ATOM 6690 N NE2 . HIS F 3 3 ? -10.620 -4.296 21.919 1.00 35.33 ? 3 HIS F NE2 1 ATOM 6691 N N . ASP F 3 4 ? -8.409 -2.396 27.927 1.00 34.15 ? 4 ASP F N 1 ATOM 6692 C CA . ASP F 3 4 ? -7.774 -1.775 29.084 1.00 27.79 ? 4 ASP F CA 1 ATOM 6693 C C . ASP F 3 4 ? -6.426 -1.143 28.733 1.00 25.72 ? 4 ASP F C 1 ATOM 6694 O O . ASP F 3 4 ? -5.470 -1.842 28.414 1.00 29.34 ? 4 ASP F O 1 ATOM 6695 C CB . ASP F 3 4 ? -7.592 -2.849 30.167 1.00 37.54 ? 4 ASP F CB 1 ATOM 6696 C CG . ASP F 3 4 ? -7.143 -2.289 31.514 1.00 35.28 ? 4 ASP F CG 1 ATOM 6697 O OD1 . ASP F 3 4 ? -6.921 -1.071 31.653 1.00 35.75 ? 4 ASP F OD1 1 ATOM 6698 O OD2 . ASP F 3 4 ? -7.002 -3.098 32.449 1.00 49.80 ? 4 ASP F OD2 1 ATOM 6699 N N . LEU F 3 5 ? -6.351 0.180 28.824 1.00 31.40 ? 5 LEU F N 1 ATOM 6700 C CA . LEU F 3 5 ? -5.128 0.920 28.501 1.00 35.20 ? 5 LEU F CA 1 ATOM 6701 C C . LEU F 3 5 ? -3.988 0.694 29.493 1.00 37.23 ? 5 LEU F C 1 ATOM 6702 O O . LEU F 3 5 ? -2.827 0.991 29.193 1.00 42.67 ? 5 LEU F O 1 ATOM 6703 C CB . LEU F 3 5 ? -5.425 2.417 28.410 1.00 30.28 ? 5 LEU F CB 1 ATOM 6704 C CG . LEU F 3 5 ? -6.513 2.784 27.410 1.00 32.00 ? 5 LEU F CG 1 ATOM 6705 C CD1 . LEU F 3 5 ? -6.709 4.287 27.368 1.00 23.31 ? 5 LEU F CD1 1 ATOM 6706 C CD2 . LEU F 3 5 ? -6.163 2.219 26.031 1.00 28.98 ? 5 LEU F CD2 1 ATOM 6707 N N . SER F 3 6 ? -4.319 0.188 30.678 1.00 38.40 ? 6 SER F N 1 ATOM 6708 C CA . SER F 3 6 ? -3.314 -0.077 31.701 1.00 38.93 ? 6 SER F CA 1 ATOM 6709 C C . SER F 3 6 ? -2.528 -1.334 31.362 1.00 36.61 ? 6 SER F C 1 ATOM 6710 O O . SER F 3 6 ? -1.312 -1.358 31.464 1.00 43.15 ? 6 SER F O 1 ATOM 6711 C CB . SER F 3 6 ? -3.968 -0.233 33.076 1.00 47.66 ? 6 SER F CB 1 ATOM 6712 O OG . SER F 3 6 ? -4.811 0.864 33.378 1.00 54.79 ? 6 SER F OG 1 ATOM 6713 N N . THR F 3 7 ? -3.233 -2.375 30.946 1.00 32.56 ? 7 THR F N 1 ATOM 6714 C CA . THR F 3 7 ? -2.621 -3.676 30.736 1.00 31.74 ? 7 THR F CA 1 ATOM 6715 C C . THR F 3 7 ? -2.434 -4.012 29.249 1.00 37.18 ? 7 THR F C 1 ATOM 6716 O O . THR F 3 7 ? -1.741 -4.967 28.894 1.00 33.53 ? 7 THR F O 1 ATOM 6717 C CB . THR F 3 7 ? -3.453 -4.774 31.435 1.00 35.82 ? 7 THR F CB 1 ATOM 6718 O OG1 . THR F 3 7 ? -4.819 -4.667 31.021 1.00 34.74 ? 7 THR F OG1 1 ATOM 6719 C CG2 . THR F 3 7 ? -3.387 -4.605 32.956 1.00 31.35 ? 7 THR F CG2 1 ATOM 6720 N N . ARG F 3 8 ? -3.046 -3.205 28.389 1.00 29.04 ? 8 ARG F N 1 ATOM 6721 C CA . ARG F 3 8 ? -3.115 -3.493 26.964 1.00 35.35 ? 8 ARG F CA 1 ATOM 6722 C C . ARG F 3 8 ? -3.779 -4.839 26.728 1.00 33.20 ? 8 ARG F C 1 ATOM 6723 O O . ARG F 3 8 ? -3.534 -5.491 25.719 1.00 43.14 ? 8 ARG F O 1 ATOM 6724 C CB . ARG F 3 8 ? -1.736 -3.423 26.295 1.00 31.96 ? 8 ARG F CB 1 ATOM 6725 C CG . ARG F 3 8 ? -0.980 -2.133 26.606 1.00 33.94 ? 8 ARG F CG 1 ATOM 6726 C CD . ARG F 3 8 ? 0.122 -1.881 25.604 1.00 28.75 ? 8 ARG F CD 1 ATOM 6727 N NE . ARG F 3 8 ? 0.940 -0.716 25.932 1.00 27.64 ? 8 ARG F NE 1 ATOM 6728 C CZ . ARG F 3 8 ? 1.943 -0.280 25.172 1.00 31.25 ? 8 ARG F CZ 1 ATOM 6729 N NH1 . ARG F 3 8 ? 2.234 -0.912 24.035 1.00 29.27 ? 8 ARG F NH1 1 ATOM 6730 N NH2 . ARG F 3 8 ? 2.646 0.787 25.534 1.00 17.95 ? 8 ARG F NH2 1 ATOM 6731 N N . ARG F 3 9 ? -4.641 -5.242 27.654 1.00 31.68 ? 9 ARG F N 1 ATOM 6732 C CA . ARG F 3 9 ? -5.356 -6.505 27.517 1.00 34.93 ? 9 ARG F CA 1 ATOM 6733 C C . ARG F 3 9 ? -6.864 -6.328 27.479 1.00 31.82 ? 9 ARG F C 1 ATOM 6734 O O . ARG F 3 9 ? -7.406 -5.381 28.055 1.00 35.86 ? 9 ARG F O 1 ATOM 6735 C CB . ARG F 3 9 ? -4.975 -7.477 28.634 1.00 26.04 ? 9 ARG F CB 1 ATOM 6736 C CG . ARG F 3 9 ? -3.585 -8.033 28.501 1.00 28.97 ? 9 ARG F CG 1 ATOM 6737 C CD . ARG F 3 9 ? -3.428 -8.860 27.229 1.00 23.40 ? 9 ARG F CD 1 ATOM 6738 N NE . ARG F 3 9 ? -4.308 -10.022 27.188 1.00 23.32 ? 9 ARG F NE 1 ATOM 6739 C CZ . ARG F 3 9 ? -4.155 -11.114 27.937 1.00 33.55 ? 9 ARG F CZ 1 ATOM 6740 N NH1 . ARG F 3 9 ? -3.159 -11.202 28.812 1.00 23.09 ? 9 ARG F NH1 1 ATOM 6741 N NH2 . ARG F 3 9 ? -5.011 -12.123 27.815 1.00 31.80 ? 9 ARG F NH2 1 ATOM 6742 N N . LEU F 3 10 ? -7.536 -7.243 26.789 1.00 29.92 ? 10 LEU F N 1 ATOM 6743 C CA . LEU F 3 10 ? -8.990 -7.313 26.848 1.00 38.23 ? 10 LEU F CA 1 ATOM 6744 C C . LEU F 3 10 ? -9.440 -7.552 28.296 1.00 39.10 ? 10 LEU F C 1 ATOM 6745 O O . LEU F 3 10 ? -8.860 -8.357 29.034 1.00 36.00 ? 10 LEU F O 1 ATOM 6746 C CB . LEU F 3 10 ? -9.525 -8.407 25.915 1.00 34.16 ? 10 LEU F CB 1 ATOM 6747 C CG . LEU F 3 10 ? -9.511 -8.108 24.414 1.00 36.75 ? 10 LEU F CG 1 ATOM 6748 C CD1 . LEU F 3 10 ? -9.855 -9.361 23.614 1.00 32.18 ? 10 LEU F CD1 1 ATOM 6749 C CD2 . LEU F 3 10 ? -10.474 -6.990 24.085 1.00 31.74 ? 10 LEU F CD2 1 ATOM 6750 N N . LYS F 3 11 ? -10.478 -6.830 28.684 1.00 38.84 ? 11 LYS F N 1 ATOM 6751 C CA . LYS F 3 11 ? -10.939 -6.771 30.059 1.00 43.87 ? 11 LYS F CA 1 ATOM 6752 C C . LYS F 3 11 ? -12.403 -7.147 30.040 1.00 50.21 ? 11 LYS F C 1 ATOM 6753 O O . LYS F 3 11 ? -13.244 -6.349 29.633 1.00 57.04 ? 11 LYS F O 1 ATOM 6754 C CB . LYS F 3 11 ? -10.784 -5.333 30.539 1.00 42.97 ? 11 LYS F CB 1 ATOM 6755 C CG . LYS F 3 11 ? -11.388 -5.037 31.872 1.00 42.03 ? 11 LYS F CG 1 ATOM 6756 C CD . LYS F 3 11 ? -10.379 -5.278 32.956 1.00 53.74 ? 11 LYS F CD 1 ATOM 6757 C CE . LYS F 3 11 ? -10.909 -4.812 34.294 1.00 61.02 ? 11 LYS F CE 1 ATOM 6758 N NZ . LYS F 3 11 ? -10.139 -5.447 35.392 1.00 57.29 ? 11 LYS F NZ 1 ATOM 6759 N N . CYS F 3 12 ? -12.733 -8.357 30.460 1.00 53.39 ? 12 CYS F N 1 ATOM 6760 C CA . CYS F 3 12 ? -14.060 -8.870 30.131 1.00 58.25 ? 12 CYS F CA 1 ATOM 6761 C C . CYS F 3 12 ? -15.101 -8.840 31.259 1.00 67.70 ? 12 CYS F C 1 ATOM 6762 O O . CYS F 3 12 ? -14.800 -8.559 32.423 1.00 69.65 ? 12 CYS F O 1 ATOM 6763 C CB . CYS F 3 12 ? -13.925 -10.259 29.516 1.00 60.08 ? 12 CYS F CB 1 ATOM 6764 S SG . CYS F 3 12 ? -12.797 -10.264 28.094 1.00 57.95 ? 12 CYS F SG 1 ATOM 6765 O OXT . CYS F 3 12 ? -16.285 -9.073 31.014 1.00 66.04 ? 12 CYS F OXT 1 HETATM 6766 P P . PO4 G 4 . ? -37.660 -21.346 22.730 0.67 59.37 ? 301 PO4 A P 1 HETATM 6767 O O1 . PO4 G 4 . ? -38.690 -21.640 21.653 0.67 45.41 ? 301 PO4 A O1 1 HETATM 6768 O O2 . PO4 G 4 . ? -37.564 -19.847 22.961 0.67 33.50 ? 301 PO4 A O2 1 HETATM 6769 O O3 . PO4 G 4 . ? -36.311 -21.890 22.291 0.67 40.44 ? 301 PO4 A O3 1 HETATM 6770 O O4 . PO4 G 4 . ? -38.090 -22.025 24.016 0.67 39.25 ? 301 PO4 A O4 1 HETATM 6771 P P . PO4 H 4 . ? -19.655 -38.670 63.865 0.63 35.73 ? 302 PO4 A P 1 HETATM 6772 O O1 . PO4 H 4 . ? -19.303 -38.995 62.431 0.63 29.33 ? 302 PO4 A O1 1 HETATM 6773 O O2 . PO4 H 4 . ? -20.123 -37.232 63.953 0.63 24.78 ? 302 PO4 A O2 1 HETATM 6774 O O3 . PO4 H 4 . ? -20.762 -39.590 64.338 0.63 45.18 ? 302 PO4 A O3 1 HETATM 6775 O O4 . PO4 H 4 . ? -18.447 -38.887 64.742 0.63 25.84 ? 302 PO4 A O4 1 HETATM 6776 C C1 . NAG I 5 . ? -16.163 -49.929 24.024 1.00 58.97 ? 301 NAG B C1 1 HETATM 6777 C C2 . NAG I 5 . ? -16.011 -48.705 23.074 1.00 53.57 ? 301 NAG B C2 1 HETATM 6778 C C3 . NAG I 5 . ? -15.644 -49.097 21.643 1.00 57.03 ? 301 NAG B C3 1 HETATM 6779 C C4 . NAG I 5 . ? -14.415 -50.045 21.671 1.00 62.63 ? 301 NAG B C4 1 HETATM 6780 C C5 . NAG I 5 . ? -14.776 -51.236 22.533 1.00 64.95 ? 301 NAG B C5 1 HETATM 6781 C C6 . NAG I 5 . ? -13.687 -52.284 22.595 1.00 80.19 ? 301 NAG B C6 1 HETATM 6782 C C7 . NAG I 5 . ? -17.517 -46.863 23.814 1.00 49.64 ? 301 NAG B C7 1 HETATM 6783 C C8 . NAG I 5 . ? -18.868 -46.233 23.644 1.00 38.04 ? 301 NAG B C8 1 HETATM 6784 N N2 . NAG I 5 . ? -17.290 -47.942 23.050 1.00 56.80 ? 301 NAG B N2 1 HETATM 6785 O O3 . NAG I 5 . ? -15.352 -47.970 20.853 1.00 58.06 ? 301 NAG B O3 1 HETATM 6786 O O4 . NAG I 5 . ? -14.075 -50.450 20.360 1.00 67.11 ? 301 NAG B O4 1 HETATM 6787 O O5 . NAG I 5 . ? -14.994 -50.770 23.859 1.00 59.51 ? 301 NAG B O5 1 HETATM 6788 O O6 . NAG I 5 . ? -14.180 -53.468 23.211 1.00 83.93 ? 301 NAG B O6 1 HETATM 6789 O O7 . NAG I 5 . ? -16.691 -46.422 24.598 1.00 47.22 ? 301 NAG B O7 1 HETATM 6790 P P . PO4 J 4 . ? -43.914 -48.446 36.623 0.66 63.14 ? 302 PO4 B P 1 HETATM 6791 O O1 . PO4 J 4 . ? -42.801 -48.866 35.680 0.66 51.36 ? 302 PO4 B O1 1 HETATM 6792 O O2 . PO4 J 4 . ? -44.624 -47.241 36.036 0.66 40.58 ? 302 PO4 B O2 1 HETATM 6793 O O3 . PO4 J 4 . ? -44.902 -49.583 36.793 0.66 48.81 ? 302 PO4 B O3 1 HETATM 6794 O O4 . PO4 J 4 . ? -43.323 -48.108 37.979 0.66 32.96 ? 302 PO4 B O4 1 HETATM 6795 O OAB . MRY K 6 . ? -19.541 -4.868 50.304 0.85 26.98 ? 301 MRY C OAB 1 HETATM 6796 C CAA . MRY K 6 . ? -18.349 -4.302 50.702 0.85 27.02 ? 301 MRY C CAA 1 HETATM 6797 C CAC . MRY K 6 . ? -17.561 -3.785 49.549 0.85 34.95 ? 301 MRY C CAC 1 HETATM 6798 O OAD . MRY K 6 . ? -18.378 -2.954 48.815 0.85 39.45 ? 301 MRY C OAD 1 HETATM 6799 C CAE . MRY K 6 . ? -16.389 -3.009 50.060 0.85 23.28 ? 301 MRY C CAE 1 HETATM 6800 O OAF . MRY K 6 . ? -15.557 -3.819 50.806 0.85 33.51 ? 301 MRY C OAF 1 HETATM 6801 C CAG . MRY K 6 . ? -15.623 -2.443 48.910 0.85 34.86 ? 301 MRY C CAG 1 HETATM 6802 O OAH . MRY K 6 . ? -14.832 -1.375 49.310 0.85 21.62 ? 301 MRY C OAH 1 HETATM 6803 C C1 . NAG L 5 . ? -15.734 9.743 20.365 1.00 53.29 ? 301 NAG D C1 1 HETATM 6804 C C2 . NAG L 5 . ? -15.588 8.409 19.584 1.00 57.95 ? 301 NAG D C2 1 HETATM 6805 C C3 . NAG L 5 . ? -16.006 8.576 18.106 1.00 59.46 ? 301 NAG D C3 1 HETATM 6806 C C4 . NAG L 5 . ? -17.311 9.339 17.969 1.00 54.34 ? 301 NAG D C4 1 HETATM 6807 C C5 . NAG L 5 . ? -17.209 10.637 18.747 1.00 64.75 ? 301 NAG D C5 1 HETATM 6808 C C6 . NAG L 5 . ? -18.453 11.486 18.681 1.00 70.47 ? 301 NAG D C6 1 HETATM 6809 C C7 . NAG L 5 . ? -13.887 6.779 20.299 1.00 50.96 ? 301 NAG D C7 1 HETATM 6810 C C8 . NAG L 5 . ? -12.429 6.418 20.270 1.00 44.61 ? 301 NAG D C8 1 HETATM 6811 N N2 . NAG L 5 . ? -14.223 7.904 19.670 1.00 52.96 ? 301 NAG D N2 1 HETATM 6812 O O3 . NAG L 5 . ? -16.129 7.284 17.514 1.00 60.61 ? 301 NAG D O3 1 HETATM 6813 O O4 . NAG L 5 . ? -17.569 9.653 16.601 1.00 63.53 ? 301 NAG D O4 1 HETATM 6814 O O5 . NAG L 5 . ? -17.002 10.313 20.125 1.00 61.83 ? 301 NAG D O5 1 HETATM 6815 O O6 . NAG L 5 . ? -18.230 12.740 19.309 1.00 69.71 ? 301 NAG D O6 1 HETATM 6816 O O7 . NAG L 5 . ? -14.712 6.072 20.875 1.00 60.86 ? 301 NAG D O7 1 HETATM 6817 P P . PO4 M 4 . ? 11.911 10.302 32.941 0.78 45.21 ? 302 PO4 D P 1 HETATM 6818 O O1 . PO4 M 4 . ? 11.164 10.917 31.784 0.78 39.06 ? 302 PO4 D O1 1 HETATM 6819 O O2 . PO4 M 4 . ? 12.988 11.229 33.465 0.78 29.70 ? 302 PO4 D O2 1 HETATM 6820 O O3 . PO4 M 4 . ? 12.524 9.002 32.463 0.78 39.25 ? 302 PO4 D O3 1 HETATM 6821 O O4 . PO4 M 4 . ? 10.909 10.055 34.040 0.78 35.01 ? 302 PO4 D O4 1 HETATM 6822 O O . HOH N 7 . ? -31.014 -26.035 33.303 1.00 25.44 ? 401 HOH A O 1 HETATM 6823 O O . HOH N 7 . ? -24.050 -37.987 52.378 1.00 30.10 ? 402 HOH A O 1 HETATM 6824 O O . HOH N 7 . ? -37.881 -21.198 12.222 1.00 37.47 ? 403 HOH A O 1 HETATM 6825 O O . HOH N 7 . ? -33.844 -19.444 13.615 1.00 28.74 ? 404 HOH A O 1 HETATM 6826 O O . HOH N 7 . ? -27.997 -14.793 32.961 1.00 37.23 ? 405 HOH A O 1 HETATM 6827 O O . HOH N 7 . ? -21.230 -45.593 66.678 1.00 33.54 ? 406 HOH A O 1 HETATM 6828 O O . HOH N 7 . ? -20.226 -12.271 25.260 1.00 29.98 ? 407 HOH A O 1 HETATM 6829 O O . HOH N 7 . ? -33.535 -37.087 32.158 1.00 31.57 ? 408 HOH A O 1 HETATM 6830 O O . HOH N 7 . ? -22.657 -25.243 34.778 1.00 27.87 ? 409 HOH A O 1 HETATM 6831 O O . HOH N 7 . ? -20.856 -40.634 58.932 1.00 27.62 ? 410 HOH A O 1 HETATM 6832 O O . HOH N 7 . ? -18.427 -27.700 49.951 1.00 13.98 ? 411 HOH A O 1 HETATM 6833 O O . HOH N 7 . ? -14.875 -20.168 48.137 1.00 30.53 ? 412 HOH A O 1 HETATM 6834 O O . HOH N 7 . ? -19.249 -18.299 45.872 1.00 24.35 ? 413 HOH A O 1 HETATM 6835 O O . HOH N 7 . ? -32.560 -35.882 56.232 1.00 23.93 ? 414 HOH A O 1 HETATM 6836 O O . HOH N 7 . ? -29.803 -19.353 9.218 1.00 26.43 ? 415 HOH A O 1 HETATM 6837 O O . HOH N 7 . ? -25.603 -32.650 26.336 1.00 26.95 ? 416 HOH A O 1 HETATM 6838 O O . HOH N 7 . ? -34.496 -38.835 56.787 1.00 32.40 ? 417 HOH A O 1 HETATM 6839 O O . HOH N 7 . ? -14.013 -18.711 10.874 1.00 29.92 ? 418 HOH A O 1 HETATM 6840 O O . HOH N 7 . ? -23.832 -21.790 4.217 1.00 32.55 ? 419 HOH A O 1 HETATM 6841 O O . HOH N 7 . ? -15.782 -31.577 18.727 1.00 27.73 ? 420 HOH A O 1 HETATM 6842 O O . HOH N 7 . ? -33.847 -22.163 23.658 1.00 20.98 ? 421 HOH A O 1 HETATM 6843 O O . HOH N 7 . ? -26.228 -25.865 33.257 1.00 31.76 ? 422 HOH A O 1 HETATM 6844 O O . HOH N 7 . ? -25.157 -38.971 49.935 1.00 29.50 ? 423 HOH A O 1 HETATM 6845 O O . HOH N 7 . ? -43.907 -39.549 56.743 1.00 30.14 ? 424 HOH A O 1 HETATM 6846 O O . HOH N 7 . ? -17.531 -30.584 56.337 1.00 23.67 ? 425 HOH A O 1 HETATM 6847 O O . HOH N 7 . ? -11.857 -20.743 8.297 1.00 35.15 ? 426 HOH A O 1 HETATM 6848 O O . HOH N 7 . ? -24.265 -27.930 37.393 1.00 31.26 ? 427 HOH A O 1 HETATM 6849 O O . HOH N 7 . ? -33.569 -30.709 24.673 1.00 23.15 ? 428 HOH A O 1 HETATM 6850 O O . HOH N 7 . ? -34.493 -27.970 23.699 1.00 30.93 ? 429 HOH A O 1 HETATM 6851 O O . HOH N 7 . ? -21.363 -42.665 60.879 1.00 31.89 ? 430 HOH A O 1 HETATM 6852 O O . HOH N 7 . ? -17.272 -35.634 51.940 1.00 25.19 ? 431 HOH A O 1 HETATM 6853 O O . HOH N 7 . ? -14.039 -39.292 1.782 1.00 36.99 ? 432 HOH A O 1 HETATM 6854 O O . HOH N 7 . ? -28.434 -15.269 14.760 1.00 36.15 ? 433 HOH A O 1 HETATM 6855 O O . HOH N 7 . ? -30.750 -26.671 29.711 1.00 25.90 ? 434 HOH A O 1 HETATM 6856 O O . HOH N 7 . ? -23.464 -23.744 10.339 1.00 26.10 ? 435 HOH A O 1 HETATM 6857 O O . HOH N 7 . ? -21.826 -11.932 38.640 1.00 26.25 ? 436 HOH A O 1 HETATM 6858 O O . HOH N 7 . ? -26.308 -34.085 48.316 1.00 19.96 ? 437 HOH A O 1 HETATM 6859 O O . HOH N 7 . ? -27.554 -45.318 6.324 1.00 25.13 ? 438 HOH A O 1 HETATM 6860 O O . HOH N 7 . ? -36.284 -18.861 11.603 1.00 39.43 ? 439 HOH A O 1 HETATM 6861 O O . HOH N 7 . ? -11.764 -37.168 7.456 1.00 38.98 ? 440 HOH A O 1 HETATM 6862 O O . HOH N 7 . ? -20.324 -13.865 23.163 1.00 36.23 ? 441 HOH A O 1 HETATM 6863 O O . HOH N 7 . ? -24.580 -23.908 32.883 1.00 32.92 ? 442 HOH A O 1 HETATM 6864 O O . HOH N 7 . ? -22.141 -41.475 14.299 1.00 23.88 ? 443 HOH A O 1 HETATM 6865 O O . HOH N 7 . ? -34.569 -24.775 34.613 1.00 29.42 ? 444 HOH A O 1 HETATM 6866 O O . HOH N 7 . ? -18.120 -40.262 8.392 1.00 28.34 ? 445 HOH A O 1 HETATM 6867 O O . HOH N 7 . ? -19.665 -25.570 18.762 1.00 24.06 ? 446 HOH A O 1 HETATM 6868 O O . HOH N 7 . ? -36.866 -28.765 16.178 1.00 24.72 ? 447 HOH A O 1 HETATM 6869 O O . HOH N 7 . ? -33.272 -12.350 21.434 1.00 42.20 ? 448 HOH A O 1 HETATM 6870 O O . HOH N 7 . ? -18.370 -22.805 55.050 1.00 29.86 ? 449 HOH A O 1 HETATM 6871 O O . HOH N 7 . ? -40.915 -37.438 60.403 1.00 39.30 ? 450 HOH A O 1 HETATM 6872 O O . HOH N 7 . ? -13.123 -28.079 66.408 1.00 30.43 ? 451 HOH A O 1 HETATM 6873 O O . HOH N 7 . ? -21.711 -14.033 14.915 1.00 39.31 ? 452 HOH A O 1 HETATM 6874 O O . HOH N 7 . ? -16.935 -19.986 18.987 1.00 43.91 ? 453 HOH A O 1 HETATM 6875 O O . HOH N 7 . ? -17.218 -16.993 44.090 1.00 20.69 ? 454 HOH A O 1 HETATM 6876 O O . HOH N 7 . ? -22.328 -37.395 -0.644 1.00 32.45 ? 455 HOH A O 1 HETATM 6877 O O . HOH N 7 . ? -20.190 -30.309 52.120 1.00 43.54 ? 456 HOH A O 1 HETATM 6878 O O . HOH N 7 . ? -13.852 -25.847 16.127 1.00 29.03 ? 457 HOH A O 1 HETATM 6879 O O . HOH N 7 . ? -22.910 -48.313 69.150 1.00 31.98 ? 458 HOH A O 1 HETATM 6880 O O . HOH N 7 . ? -34.765 -19.683 47.752 1.00 23.64 ? 459 HOH A O 1 HETATM 6881 O O . HOH N 7 . ? -19.041 -16.619 20.542 1.00 29.11 ? 460 HOH A O 1 HETATM 6882 O O . HOH N 7 . ? -29.069 -49.515 57.140 1.00 30.54 ? 461 HOH A O 1 HETATM 6883 O O . HOH N 7 . ? -18.284 -34.197 55.433 1.00 31.14 ? 462 HOH A O 1 HETATM 6884 O O . HOH N 7 . ? -34.311 -22.192 12.553 1.00 29.03 ? 463 HOH A O 1 HETATM 6885 O O . HOH N 7 . ? -23.516 -29.587 0.546 1.00 24.86 ? 464 HOH A O 1 HETATM 6886 O O . HOH N 7 . ? -21.585 -28.476 65.833 1.00 22.47 ? 465 HOH A O 1 HETATM 6887 O O . HOH N 7 . ? -20.138 -25.665 44.342 1.00 23.33 ? 466 HOH A O 1 HETATM 6888 O O . HOH N 7 . ? -24.293 -13.979 57.300 1.00 31.50 ? 467 HOH A O 1 HETATM 6889 O O . HOH N 7 . ? -23.645 -26.383 -0.879 1.00 27.78 ? 468 HOH A O 1 HETATM 6890 O O . HOH N 7 . ? -19.588 -34.771 46.698 1.00 22.88 ? 469 HOH A O 1 HETATM 6891 O O . HOH N 7 . ? -24.876 -8.479 54.104 1.00 33.86 ? 470 HOH A O 1 HETATM 6892 O O . HOH N 7 . ? -25.602 -17.583 60.609 1.00 18.09 ? 471 HOH A O 1 HETATM 6893 O O . HOH N 7 . ? -12.018 -31.905 12.775 1.00 30.29 ? 472 HOH A O 1 HETATM 6894 O O . HOH N 7 . ? -38.712 -27.499 19.232 1.00 38.54 ? 473 HOH A O 1 HETATM 6895 O O . HOH N 7 . ? -31.542 -22.998 40.911 1.00 17.51 ? 474 HOH A O 1 HETATM 6896 O O . HOH N 7 . ? -21.501 -41.190 54.826 1.00 37.48 ? 475 HOH A O 1 HETATM 6897 O O . HOH N 7 . ? -20.019 -41.671 2.000 1.00 32.00 ? 476 HOH A O 1 HETATM 6898 O O . HOH N 7 . ? -25.603 -42.483 8.124 1.00 24.34 ? 477 HOH A O 1 HETATM 6899 O O . HOH N 7 . ? -23.938 -32.613 40.843 1.00 31.28 ? 478 HOH A O 1 HETATM 6900 O O . HOH N 7 . ? -31.373 -24.504 39.472 1.00 33.11 ? 479 HOH A O 1 HETATM 6901 O O . HOH N 7 . ? -15.465 -33.540 53.190 1.00 25.40 ? 480 HOH A O 1 HETATM 6902 O O . HOH N 7 . ? -27.488 -40.703 51.889 1.00 45.50 ? 481 HOH A O 1 HETATM 6903 O O . HOH N 7 . ? -11.486 -32.096 1.691 1.00 42.77 ? 482 HOH A O 1 HETATM 6904 O O . HOH N 7 . ? -27.296 -25.033 2.266 1.00 27.40 ? 483 HOH A O 1 HETATM 6905 O O . HOH N 7 . ? -18.742 -42.792 2.858 1.00 41.23 ? 484 HOH A O 1 HETATM 6906 O O . HOH N 7 . ? -19.234 -39.680 51.277 1.00 34.89 ? 485 HOH A O 1 HETATM 6907 O O . HOH N 7 . ? -16.319 -38.370 14.495 1.00 34.92 ? 486 HOH A O 1 HETATM 6908 O O . HOH N 7 . ? -22.553 -8.064 57.905 1.00 25.71 ? 487 HOH A O 1 HETATM 6909 O O . HOH N 7 . ? -31.796 -28.485 1.209 1.00 22.00 ? 488 HOH A O 1 HETATM 6910 O O . HOH N 7 . ? -21.318 -25.389 65.719 1.00 23.35 ? 489 HOH A O 1 HETATM 6911 O O . HOH N 7 . ? -21.482 -35.574 -1.511 1.00 36.40 ? 490 HOH A O 1 HETATM 6912 O O . HOH N 7 . ? -15.731 -20.227 57.696 1.00 36.11 ? 491 HOH A O 1 HETATM 6913 O O . HOH N 7 . ? -21.814 -19.957 34.916 1.00 33.74 ? 492 HOH A O 1 HETATM 6914 O O . HOH N 7 . ? -17.616 -31.564 54.061 1.00 26.18 ? 493 HOH A O 1 HETATM 6915 O O . HOH N 7 . ? -37.015 -32.815 25.088 1.00 23.03 ? 494 HOH A O 1 HETATM 6916 O O . HOH N 7 . ? -17.566 -45.409 6.376 1.00 33.76 ? 495 HOH A O 1 HETATM 6917 O O . HOH N 7 . ? -17.486 -14.836 51.359 1.00 25.11 ? 496 HOH A O 1 HETATM 6918 O O . HOH N 7 . ? -16.904 -18.862 61.560 1.00 41.44 ? 497 HOH A O 1 HETATM 6919 O O . HOH N 7 . ? -21.975 -9.587 49.933 1.00 36.13 ? 498 HOH A O 1 HETATM 6920 O O . HOH N 7 . ? -20.744 -20.103 37.657 1.00 28.95 ? 499 HOH A O 1 HETATM 6921 O O . HOH N 7 . ? -31.837 -36.638 73.918 1.00 34.78 ? 500 HOH A O 1 HETATM 6922 O O . HOH N 7 . ? -32.557 -26.783 36.527 1.00 49.46 ? 501 HOH A O 1 HETATM 6923 O O . HOH N 7 . ? -21.492 -39.842 52.257 1.00 34.64 ? 502 HOH A O 1 HETATM 6924 O O . HOH N 7 . ? -17.287 -18.965 48.486 1.00 20.93 ? 503 HOH A O 1 HETATM 6925 O O . HOH N 7 . ? -26.376 -36.466 47.577 1.00 20.18 ? 504 HOH A O 1 HETATM 6926 O O . HOH N 7 . ? -16.315 -28.662 49.553 1.00 40.76 ? 505 HOH A O 1 HETATM 6927 O O . HOH N 7 . ? -29.495 -36.945 74.883 1.00 36.94 ? 506 HOH A O 1 HETATM 6928 O O . HOH N 7 . ? -15.189 -36.942 50.299 1.00 34.42 ? 507 HOH A O 1 HETATM 6929 O O . HOH N 7 . ? -40.645 -35.832 59.375 1.00 42.87 ? 508 HOH A O 1 HETATM 6930 O O . HOH N 7 . ? -18.367 -39.825 16.205 1.00 30.52 ? 509 HOH A O 1 HETATM 6931 O O . HOH N 7 . ? -36.045 -30.191 26.316 1.00 21.50 ? 510 HOH A O 1 HETATM 6932 O O . HOH O 7 . ? -47.368 -41.452 6.748 1.00 35.20 ? 401 HOH B O 1 HETATM 6933 O O . HOH O 7 . ? -27.462 -59.829 16.030 1.00 40.13 ? 402 HOH B O 1 HETATM 6934 O O . HOH O 7 . ? -37.580 -43.750 4.132 1.00 35.40 ? 403 HOH B O 1 HETATM 6935 O O . HOH O 7 . ? -29.482 -59.155 17.036 1.00 47.23 ? 404 HOH B O 1 HETATM 6936 O O . HOH O 7 . ? -22.273 -43.030 22.006 1.00 28.75 ? 405 HOH B O 1 HETATM 6937 O O . HOH O 7 . ? -37.156 -23.058 44.976 1.00 21.55 ? 406 HOH B O 1 HETATM 6938 O O . HOH O 7 . ? -32.704 -39.475 38.008 1.00 17.92 ? 407 HOH B O 1 HETATM 6939 O O . HOH O 7 . ? -36.980 -40.654 8.677 1.00 25.46 ? 408 HOH B O 1 HETATM 6940 O O . HOH O 7 . ? -21.077 -39.206 15.996 1.00 17.88 ? 409 HOH B O 1 HETATM 6941 O O . HOH O 7 . ? -29.872 -61.742 26.191 1.00 43.83 ? 410 HOH B O 1 HETATM 6942 O O . HOH O 7 . ? -48.356 -31.661 53.104 1.00 20.71 ? 411 HOH B O 1 HETATM 6943 O O . HOH O 7 . ? -36.951 -50.769 27.404 1.00 31.08 ? 412 HOH B O 1 HETATM 6944 O O . HOH O 7 . ? -30.572 -47.586 33.206 1.00 23.82 ? 413 HOH B O 1 HETATM 6945 O O . HOH O 7 . ? -46.807 -46.777 11.096 1.00 31.26 ? 414 HOH B O 1 HETATM 6946 O O . HOH O 7 . ? -18.637 -47.482 19.534 1.00 35.79 ? 415 HOH B O 1 HETATM 6947 O O . HOH O 7 . ? -28.771 -34.769 5.892 1.00 24.70 ? 416 HOH B O 1 HETATM 6948 O O . HOH O 7 . ? -14.612 -39.011 25.690 1.00 40.65 ? 417 HOH B O 1 HETATM 6949 O O . HOH O 7 . ? -38.410 -54.296 22.321 1.00 32.49 ? 418 HOH B O 1 HETATM 6950 O O . HOH O 7 . ? -43.961 -31.709 39.353 1.00 24.83 ? 419 HOH B O 1 HETATM 6951 O O . HOH O 7 . ? -49.940 -37.000 44.098 1.00 30.79 ? 420 HOH B O 1 HETATM 6952 O O . HOH O 7 . ? -47.469 -49.505 37.733 1.00 39.64 ? 421 HOH B O 1 HETATM 6953 O O . HOH O 7 . ? -17.033 -46.751 8.409 1.00 35.17 ? 422 HOH B O 1 HETATM 6954 O O . HOH O 7 . ? -30.304 -37.842 38.322 1.00 28.03 ? 423 HOH B O 1 HETATM 6955 O O . HOH O 7 . ? -21.155 -36.234 21.018 1.00 24.76 ? 424 HOH B O 1 HETATM 6956 O O . HOH O 7 . ? -24.967 -46.981 37.031 1.00 31.37 ? 425 HOH B O 1 HETATM 6957 O O . HOH O 7 . ? -34.893 -40.887 7.112 1.00 21.09 ? 426 HOH B O 1 HETATM 6958 O O . HOH O 7 . ? -26.374 -46.850 50.664 1.00 31.70 ? 427 HOH B O 1 HETATM 6959 O O . HOH O 7 . ? -27.579 -46.069 36.160 1.00 21.49 ? 428 HOH B O 1 HETATM 6960 O O . HOH O 7 . ? -28.632 -54.461 6.843 1.00 29.76 ? 429 HOH B O 1 HETATM 6961 O O . HOH O 7 . ? -41.366 -37.537 19.902 1.00 20.89 ? 430 HOH B O 1 HETATM 6962 O O . HOH O 7 . ? -40.763 -42.552 54.639 1.00 26.63 ? 431 HOH B O 1 HETATM 6963 O O . HOH O 7 . ? -19.543 -52.218 18.681 1.00 33.43 ? 432 HOH B O 1 HETATM 6964 O O . HOH O 7 . ? -18.368 -45.946 11.988 1.00 34.64 ? 433 HOH B O 1 HETATM 6965 O O . HOH O 7 . ? -19.500 -49.840 22.143 1.00 36.68 ? 434 HOH B O 1 HETATM 6966 O O . HOH O 7 . ? -34.588 -43.494 30.427 1.00 21.92 ? 435 HOH B O 1 HETATM 6967 O O . HOH O 7 . ? -22.918 -48.894 41.062 1.00 31.09 ? 436 HOH B O 1 HETATM 6968 O O . HOH O 7 . ? -42.420 -20.683 43.806 1.00 39.09 ? 437 HOH B O 1 HETATM 6969 O O . HOH O 7 . ? -22.143 -49.255 33.981 1.00 29.94 ? 438 HOH B O 1 HETATM 6970 O O . HOH O 7 . ? -37.027 -55.406 8.194 1.00 34.34 ? 439 HOH B O 1 HETATM 6971 O O . HOH O 7 . ? -36.355 -53.475 44.556 1.00 32.00 ? 440 HOH B O 1 HETATM 6972 O O . HOH O 7 . ? -40.640 -28.546 38.162 1.00 34.93 ? 441 HOH B O 1 HETATM 6973 O O . HOH O 7 . ? -34.634 -29.932 38.835 1.00 28.31 ? 442 HOH B O 1 HETATM 6974 O O . HOH O 7 . ? -41.835 -34.835 4.797 1.00 43.00 ? 443 HOH B O 1 HETATM 6975 O O . HOH O 7 . ? -29.106 -43.794 2.671 1.00 22.84 ? 444 HOH B O 1 HETATM 6976 O O . HOH O 7 . ? -26.398 -61.181 23.955 1.00 32.30 ? 445 HOH B O 1 HETATM 6977 O O . HOH O 7 . ? -38.352 -33.094 38.723 1.00 25.85 ? 446 HOH B O 1 HETATM 6978 O O . HOH O 7 . ? -42.480 -52.079 4.879 1.00 38.02 ? 447 HOH B O 1 HETATM 6979 O O . HOH O 7 . ? -29.790 -58.569 31.144 1.00 35.97 ? 448 HOH B O 1 HETATM 6980 O O . HOH O 7 . ? -28.713 -37.651 48.575 1.00 39.70 ? 449 HOH B O 1 HETATM 6981 O O . HOH O 7 . ? -37.303 -44.337 35.957 1.00 30.29 ? 450 HOH B O 1 HETATM 6982 O O . HOH O 7 . ? -21.140 -42.784 50.009 1.00 33.30 ? 451 HOH B O 1 HETATM 6983 O O . HOH O 7 . ? -27.862 -36.436 45.358 1.00 41.27 ? 452 HOH B O 1 HETATM 6984 O O . HOH O 7 . ? -51.000 -38.992 45.705 1.00 22.58 ? 453 HOH B O 1 HETATM 6985 O O . HOH O 7 . ? -49.132 -57.916 13.724 1.00 41.04 ? 454 HOH B O 1 HETATM 6986 O O . HOH O 7 . ? -44.311 -23.112 44.839 1.00 27.17 ? 455 HOH B O 1 HETATM 6987 O O . HOH O 7 . ? -36.598 -55.122 20.275 1.00 32.76 ? 456 HOH B O 1 HETATM 6988 O O . HOH O 7 . ? -18.708 -52.802 23.525 1.00 40.98 ? 457 HOH B O 1 HETATM 6989 O O . HOH O 7 . ? -30.943 -54.524 4.984 1.00 30.37 ? 458 HOH B O 1 HETATM 6990 O O . HOH O 7 . ? -37.784 -36.547 37.276 1.00 26.76 ? 459 HOH B O 1 HETATM 6991 O O . HOH O 7 . ? -38.878 -34.327 19.098 1.00 26.86 ? 460 HOH B O 1 HETATM 6992 O O . HOH O 7 . ? -33.979 -26.807 38.508 1.00 21.26 ? 461 HOH B O 1 HETATM 6993 O O . HOH O 7 . ? -37.198 -28.995 38.044 1.00 35.74 ? 462 HOH B O 1 HETATM 6994 O O . HOH O 7 . ? -32.865 -54.806 -0.429 1.00 29.62 ? 463 HOH B O 1 HETATM 6995 O O . HOH O 7 . ? -36.586 -50.151 2.420 1.00 33.71 ? 464 HOH B O 1 HETATM 6996 O O . HOH O 7 . ? -49.826 -30.197 56.955 1.00 41.29 ? 465 HOH B O 1 HETATM 6997 O O . HOH O 7 . ? -22.065 -39.804 41.273 1.00 32.56 ? 466 HOH B O 1 HETATM 6998 O O . HOH O 7 . ? -20.436 -54.906 36.842 1.00 39.94 ? 467 HOH B O 1 HETATM 6999 O O . HOH O 7 . ? -45.583 -42.359 42.132 1.00 25.56 ? 468 HOH B O 1 HETATM 7000 O O . HOH O 7 . ? -44.217 -36.209 56.433 1.00 23.47 ? 469 HOH B O 1 HETATM 7001 O O . HOH O 7 . ? -19.869 -51.212 46.219 1.00 30.72 ? 470 HOH B O 1 HETATM 7002 O O . HOH O 7 . ? -25.582 -52.457 7.084 1.00 24.18 ? 471 HOH B O 1 HETATM 7003 O O . HOH O 7 . ? -25.911 -51.107 4.830 1.00 32.88 ? 472 HOH B O 1 HETATM 7004 O O . HOH O 7 . ? -40.804 -19.896 46.208 1.00 28.70 ? 473 HOH B O 1 HETATM 7005 O O . HOH O 7 . ? -41.872 -43.403 1.781 1.00 33.00 ? 474 HOH B O 1 HETATM 7006 O O . HOH O 7 . ? -23.702 -64.904 27.733 1.00 35.08 ? 475 HOH B O 1 HETATM 7007 O O . HOH O 7 . ? -39.573 -22.842 38.627 1.00 38.36 ? 476 HOH B O 1 HETATM 7008 O O . HOH O 7 . ? -19.643 -43.052 14.484 1.00 36.28 ? 477 HOH B O 1 HETATM 7009 O O . HOH O 7 . ? -50.912 -37.221 58.948 1.00 31.16 ? 478 HOH B O 1 HETATM 7010 O O . HOH O 7 . ? -47.645 -56.723 9.982 1.00 42.60 ? 479 HOH B O 1 HETATM 7011 O O . HOH O 7 . ? -34.235 -33.466 37.553 1.00 34.33 ? 480 HOH B O 1 HETATM 7012 O O . HOH O 7 . ? -27.362 -63.793 25.392 1.00 44.97 ? 481 HOH B O 1 HETATM 7013 O O . HOH O 7 . ? -46.860 -54.729 9.008 1.00 43.54 ? 482 HOH B O 1 HETATM 7014 O O . HOH O 7 . ? -37.467 -24.087 39.547 1.00 33.28 ? 483 HOH B O 1 HETATM 7015 O O . HOH O 7 . ? -32.219 -36.696 38.244 1.00 31.40 ? 484 HOH B O 1 HETATM 7016 O O . HOH O 7 . ? -30.431 -45.845 1.813 1.00 30.76 ? 485 HOH B O 1 HETATM 7017 O O . HOH O 7 . ? -29.278 -62.974 22.975 1.00 45.86 ? 486 HOH B O 1 HETATM 7018 O O . HOH O 7 . ? -37.064 -34.442 37.718 1.00 35.80 ? 487 HOH B O 1 HETATM 7019 O O . HOH O 7 . ? -18.503 -50.227 19.397 1.00 37.87 ? 488 HOH B O 1 HETATM 7020 O O . HOH O 7 . ? -45.183 -41.305 39.935 1.00 30.69 ? 489 HOH B O 1 HETATM 7021 O O . HOH O 7 . ? -52.773 -29.738 43.576 1.00 28.49 ? 490 HOH B O 1 HETATM 7022 O O . HOH O 7 . ? -40.908 -31.010 38.741 1.00 34.89 ? 491 HOH B O 1 HETATM 7023 O O . HOH O 7 . ? -22.790 -46.671 34.713 1.00 32.46 ? 492 HOH B O 1 HETATM 7024 O O . HOH O 7 . ? -38.061 -53.249 28.734 1.00 41.70 ? 493 HOH B O 1 HETATM 7025 O O . HOH O 7 . ? -47.405 -23.222 42.661 1.00 22.05 ? 494 HOH B O 1 HETATM 7026 O O . HOH O 7 . ? -26.867 -55.652 7.441 1.00 36.56 ? 495 HOH B O 1 HETATM 7027 O O . HOH O 7 . ? -46.692 -22.644 45.049 1.00 19.73 ? 496 HOH B O 1 HETATM 7028 O O . HOH O 7 . ? -47.578 -20.406 45.486 1.00 29.66 ? 497 HOH B O 1 HETATM 7029 O O . HOH P 7 . ? 11.839 8.548 53.023 1.00 45.16 ? 401 HOH C O 1 HETATM 7030 O O . HOH P 7 . ? -3.378 -2.717 46.567 1.00 47.39 ? 402 HOH C O 1 HETATM 7031 O O . HOH P 7 . ? 4.998 -19.157 38.437 1.00 35.71 ? 403 HOH C O 1 HETATM 7032 O O . HOH P 7 . ? -12.881 7.934 59.105 1.00 26.75 ? 404 HOH C O 1 HETATM 7033 O O . HOH P 7 . ? 0.645 12.029 65.023 1.00 40.62 ? 405 HOH C O 1 HETATM 7034 O O . HOH P 7 . ? -5.034 3.442 49.746 1.00 19.49 ? 406 HOH C O 1 HETATM 7035 O O . HOH P 7 . ? -6.915 9.100 53.819 1.00 36.85 ? 407 HOH C O 1 HETATM 7036 O O . HOH P 7 . ? 7.619 -18.169 10.774 1.00 38.58 ? 408 HOH C O 1 HETATM 7037 O O . HOH P 7 . ? -16.980 -21.023 5.678 1.00 31.66 ? 409 HOH C O 1 HETATM 7038 O O . HOH P 7 . ? -18.639 -0.791 48.234 1.00 40.61 ? 410 HOH C O 1 HETATM 7039 O O . HOH P 7 . ? -11.273 8.607 63.671 1.00 26.80 ? 411 HOH C O 1 HETATM 7040 O O . HOH P 7 . ? -4.918 -12.617 30.869 1.00 27.13 ? 412 HOH C O 1 HETATM 7041 O O . HOH P 7 . ? -9.123 -3.634 -2.760 1.00 36.23 ? 413 HOH C O 1 HETATM 7042 O O . HOH P 7 . ? -7.663 -8.952 -1.636 1.00 28.66 ? 414 HOH C O 1 HETATM 7043 O O . HOH P 7 . ? -10.175 -8.927 66.732 1.00 38.00 ? 415 HOH C O 1 HETATM 7044 O O . HOH P 7 . ? -14.337 -19.898 25.819 1.00 23.74 ? 416 HOH C O 1 HETATM 7045 O O . HOH P 7 . ? -18.818 -9.331 10.612 1.00 28.19 ? 417 HOH C O 1 HETATM 7046 O O . HOH P 7 . ? -8.635 1.321 48.966 1.00 21.48 ? 418 HOH C O 1 HETATM 7047 O O . HOH P 7 . ? 5.519 -16.349 41.775 1.00 36.89 ? 419 HOH C O 1 HETATM 7048 O O . HOH P 7 . ? -19.046 -11.124 0.141 1.00 40.13 ? 420 HOH C O 1 HETATM 7049 O O . HOH P 7 . ? -5.748 -6.493 23.745 1.00 28.34 ? 421 HOH C O 1 HETATM 7050 O O . HOH P 7 . ? 7.084 -18.766 21.994 1.00 47.11 ? 422 HOH C O 1 HETATM 7051 O O . HOH P 7 . ? -13.870 -5.441 53.560 1.00 22.14 ? 423 HOH C O 1 HETATM 7052 O O . HOH P 7 . ? 3.179 -17.147 22.318 1.00 31.62 ? 424 HOH C O 1 HETATM 7053 O O . HOH P 7 . ? 0.576 -0.581 53.465 1.00 19.68 ? 425 HOH C O 1 HETATM 7054 O O . HOH P 7 . ? 3.683 -19.903 12.165 1.00 32.64 ? 426 HOH C O 1 HETATM 7055 O O . HOH P 7 . ? -8.689 -8.939 32.665 1.00 47.41 ? 427 HOH C O 1 HETATM 7056 O O . HOH P 7 . ? 2.536 3.151 53.761 1.00 17.62 ? 428 HOH C O 1 HETATM 7057 O O . HOH P 7 . ? -13.562 4.568 8.136 1.00 35.48 ? 429 HOH C O 1 HETATM 7058 O O . HOH P 7 . ? 2.656 -11.991 36.226 1.00 25.04 ? 430 HOH C O 1 HETATM 7059 O O . HOH P 7 . ? -9.525 -17.637 58.933 1.00 36.23 ? 431 HOH C O 1 HETATM 7060 O O . HOH P 7 . ? 7.753 -21.948 21.008 1.00 36.02 ? 432 HOH C O 1 HETATM 7061 O O . HOH P 7 . ? -11.000 -8.058 35.060 1.00 53.96 ? 433 HOH C O 1 HETATM 7062 O O . HOH P 7 . ? 4.574 -7.490 26.784 1.00 29.65 ? 434 HOH C O 1 HETATM 7063 O O . HOH P 7 . ? -6.685 -22.661 10.651 1.00 38.73 ? 435 HOH C O 1 HETATM 7064 O O . HOH P 7 . ? -13.596 -2.339 52.518 1.00 18.35 ? 436 HOH C O 1 HETATM 7065 O O . HOH P 7 . ? -11.614 4.652 55.318 1.00 19.92 ? 437 HOH C O 1 HETATM 7066 O O . HOH P 7 . ? 3.307 -10.693 21.639 1.00 26.12 ? 438 HOH C O 1 HETATM 7067 O O . HOH P 7 . ? -1.269 -24.749 14.016 1.00 33.35 ? 439 HOH C O 1 HETATM 7068 O O . HOH P 7 . ? -0.131 -11.969 28.143 1.00 24.91 ? 440 HOH C O 1 HETATM 7069 O O . HOH P 7 . ? -0.441 -13.168 37.329 1.00 20.26 ? 441 HOH C O 1 HETATM 7070 O O . HOH P 7 . ? -7.050 -10.633 35.077 1.00 31.48 ? 442 HOH C O 1 HETATM 7071 O O . HOH P 7 . ? -11.552 -6.621 49.460 1.00 32.99 ? 443 HOH C O 1 HETATM 7072 O O . HOH P 7 . ? -10.696 5.997 57.459 1.00 24.76 ? 444 HOH C O 1 HETATM 7073 O O . HOH P 7 . ? -6.234 12.420 58.099 1.00 30.27 ? 445 HOH C O 1 HETATM 7074 O O . HOH P 7 . ? 2.406 -8.762 22.302 1.00 24.73 ? 446 HOH C O 1 HETATM 7075 O O . HOH P 7 . ? 2.891 -13.389 33.117 1.00 27.31 ? 447 HOH C O 1 HETATM 7076 O O . HOH P 7 . ? -12.906 -1.116 5.305 1.00 33.43 ? 448 HOH C O 1 HETATM 7077 O O . HOH P 7 . ? 0.206 -14.909 39.397 1.00 17.13 ? 449 HOH C O 1 HETATM 7078 O O . HOH P 7 . ? -6.678 -16.623 8.463 1.00 23.28 ? 450 HOH C O 1 HETATM 7079 O O . HOH P 7 . ? -0.068 -31.496 22.764 1.00 35.18 ? 451 HOH C O 1 HETATM 7080 O O . HOH P 7 . ? 8.411 -12.221 14.336 1.00 36.89 ? 452 HOH C O 1 HETATM 7081 O O . HOH P 7 . ? -10.630 -22.214 7.550 1.00 35.17 ? 453 HOH C O 1 HETATM 7082 O O . HOH P 7 . ? -0.130 -21.080 8.456 1.00 32.98 ? 454 HOH C O 1 HETATM 7083 O O . HOH P 7 . ? -6.427 11.348 59.880 1.00 34.35 ? 455 HOH C O 1 HETATM 7084 O O . HOH P 7 . ? -12.954 -19.141 44.270 1.00 31.60 ? 456 HOH C O 1 HETATM 7085 O O . HOH P 7 . ? 0.044 -3.089 33.530 1.00 26.48 ? 457 HOH C O 1 HETATM 7086 O O . HOH P 7 . ? 2.063 1.274 62.181 1.00 33.94 ? 458 HOH C O 1 HETATM 7087 O O . HOH P 7 . ? 2.005 -21.218 4.930 1.00 39.43 ? 459 HOH C O 1 HETATM 7088 O O . HOH P 7 . ? -14.804 -10.425 19.677 1.00 37.34 ? 460 HOH C O 1 HETATM 7089 O O . HOH P 7 . ? -11.304 10.312 59.818 1.00 34.27 ? 461 HOH C O 1 HETATM 7090 O O . HOH P 7 . ? -6.757 8.751 66.982 1.00 36.13 ? 462 HOH C O 1 HETATM 7091 O O . HOH P 7 . ? -10.034 -7.931 63.397 1.00 29.73 ? 463 HOH C O 1 HETATM 7092 O O . HOH P 7 . ? -1.177 -13.424 60.697 1.00 24.76 ? 464 HOH C O 1 HETATM 7093 O O . HOH P 7 . ? -4.880 -23.476 10.012 1.00 39.57 ? 465 HOH C O 1 HETATM 7094 O O . HOH P 7 . ? -12.928 -4.212 -2.874 1.00 41.84 ? 466 HOH C O 1 HETATM 7095 O O . HOH P 7 . ? -13.676 -20.456 1.007 1.00 30.87 ? 467 HOH C O 1 HETATM 7096 O O . HOH P 7 . ? -2.224 -23.746 31.447 1.00 37.99 ? 468 HOH C O 1 HETATM 7097 O O . HOH P 7 . ? 6.319 -10.578 14.130 1.00 31.80 ? 469 HOH C O 1 HETATM 7098 O O . HOH P 7 . ? 0.447 -19.660 45.901 1.00 27.88 ? 470 HOH C O 1 HETATM 7099 O O . HOH P 7 . ? -13.990 3.843 3.200 1.00 37.38 ? 471 HOH C O 1 HETATM 7100 O O . HOH P 7 . ? -2.380 -2.272 44.507 1.00 32.59 ? 472 HOH C O 1 HETATM 7101 O O . HOH P 7 . ? -10.874 -14.722 16.927 1.00 23.50 ? 473 HOH C O 1 HETATM 7102 O O . HOH P 7 . ? -14.415 -4.374 12.390 1.00 20.23 ? 474 HOH C O 1 HETATM 7103 O O . HOH P 7 . ? -15.803 -15.896 58.888 1.00 34.12 ? 475 HOH C O 1 HETATM 7104 O O . HOH P 7 . ? -17.125 -15.352 25.180 1.00 33.46 ? 476 HOH C O 1 HETATM 7105 O O . HOH P 7 . ? -13.513 -21.012 50.427 1.00 31.37 ? 477 HOH C O 1 HETATM 7106 O O . HOH P 7 . ? 7.365 1.862 58.790 1.00 44.23 ? 478 HOH C O 1 HETATM 7107 O O . HOH P 7 . ? -6.105 0.871 69.600 1.00 23.13 ? 479 HOH C O 1 HETATM 7108 O O . HOH P 7 . ? -6.003 1.808 5.041 1.00 21.97 ? 480 HOH C O 1 HETATM 7109 O O . HOH P 7 . ? -1.122 8.514 51.202 1.00 34.93 ? 481 HOH C O 1 HETATM 7110 O O . HOH P 7 . ? 1.879 -7.689 65.012 1.00 33.37 ? 482 HOH C O 1 HETATM 7111 O O . HOH P 7 . ? -16.697 -13.620 57.682 1.00 37.62 ? 483 HOH C O 1 HETATM 7112 O O . HOH P 7 . ? -14.122 -1.646 45.260 1.00 30.23 ? 484 HOH C O 1 HETATM 7113 O O . HOH P 7 . ? 8.081 -12.029 16.748 1.00 35.91 ? 485 HOH C O 1 HETATM 7114 O O . HOH P 7 . ? -16.984 -16.466 49.562 1.00 19.49 ? 486 HOH C O 1 HETATM 7115 O O . HOH P 7 . ? 5.588 -16.081 3.993 1.00 39.37 ? 487 HOH C O 1 HETATM 7116 O O . HOH P 7 . ? -12.110 -2.987 43.293 1.00 22.08 ? 488 HOH C O 1 HETATM 7117 O O . HOH P 7 . ? -17.748 -5.911 52.826 1.00 36.78 ? 489 HOH C O 1 HETATM 7118 O O . HOH P 7 . ? 5.848 -6.096 22.513 1.00 32.84 ? 490 HOH C O 1 HETATM 7119 O O . HOH P 7 . ? 12.067 2.638 54.143 1.00 28.30 ? 491 HOH C O 1 HETATM 7120 O O . HOH P 7 . ? 8.756 -23.830 15.975 1.00 41.36 ? 492 HOH C O 1 HETATM 7121 O O . HOH P 7 . ? 2.661 -1.685 63.005 1.00 29.17 ? 493 HOH C O 1 HETATM 7122 O O . HOH P 7 . ? -14.637 -10.577 42.273 1.00 40.09 ? 494 HOH C O 1 HETATM 7123 O O . HOH P 7 . ? -20.103 -8.883 51.007 1.00 33.36 ? 495 HOH C O 1 HETATM 7124 O O . HOH P 7 . ? 3.920 -19.983 4.476 1.00 44.63 ? 496 HOH C O 1 HETATM 7125 O O . HOH P 7 . ? 7.586 -12.885 7.092 1.00 35.49 ? 497 HOH C O 1 HETATM 7126 O O . HOH P 7 . ? -16.899 -7.938 52.325 1.00 35.73 ? 498 HOH C O 1 HETATM 7127 O O . HOH P 7 . ? 6.011 -14.030 37.810 1.00 31.88 ? 499 HOH C O 1 HETATM 7128 O O . HOH P 7 . ? -14.766 -13.551 64.347 1.00 49.26 ? 500 HOH C O 1 HETATM 7129 O O . HOH P 7 . ? 12.546 10.850 52.593 1.00 37.89 ? 501 HOH C O 1 HETATM 7130 O O . HOH P 7 . ? -11.161 2.925 49.100 1.00 32.37 ? 502 HOH C O 1 HETATM 7131 O O . HOH P 7 . ? -0.743 -12.838 63.404 1.00 39.84 ? 503 HOH C O 1 HETATM 7132 O O . HOH P 7 . ? -4.640 12.406 61.954 1.00 45.91 ? 504 HOH C O 1 HETATM 7133 O O . HOH P 7 . ? 8.921 -15.015 6.118 1.00 30.62 ? 505 HOH C O 1 HETATM 7134 O O . HOH P 7 . ? -12.481 -7.544 -4.425 1.00 37.68 ? 506 HOH C O 1 HETATM 7135 O O . HOH P 7 . ? -15.372 -17.980 59.451 1.00 32.99 ? 507 HOH C O 1 HETATM 7136 O O . HOH P 7 . ? 13.134 6.527 54.534 1.00 33.77 ? 508 HOH C O 1 HETATM 7137 O O . HOH P 7 . ? 6.652 -6.509 27.866 1.00 43.03 ? 509 HOH C O 1 HETATM 7138 O O . HOH P 7 . ? 3.548 -8.058 62.687 1.00 29.65 ? 510 HOH C O 1 HETATM 7139 O O . HOH P 7 . ? -13.555 -0.749 13.057 1.00 29.11 ? 511 HOH C O 1 HETATM 7140 O O . HOH P 7 . ? 4.883 -8.471 23.956 1.00 25.09 ? 512 HOH C O 1 HETATM 7141 O O . HOH Q 7 . ? 9.489 -1.196 17.185 1.00 32.15 ? 401 HOH D O 1 HETATM 7142 O O . HOH Q 7 . ? 0.622 2.136 34.977 1.00 20.62 ? 402 HOH D O 1 HETATM 7143 O O . HOH Q 7 . ? 17.331 -6.658 51.914 1.00 30.97 ? 403 HOH D O 1 HETATM 7144 O O . HOH Q 7 . ? 14.470 4.271 16.741 1.00 34.42 ? 404 HOH D O 1 HETATM 7145 O O . HOH Q 7 . ? 10.781 -1.181 56.163 1.00 34.02 ? 405 HOH D O 1 HETATM 7146 O O . HOH Q 7 . ? -2.362 -5.665 3.204 1.00 28.57 ? 406 HOH D O 1 HETATM 7147 O O . HOH Q 7 . ? 14.081 4.976 39.600 1.00 30.46 ? 407 HOH D O 1 HETATM 7148 O O . HOH Q 7 . ? -5.667 9.784 46.785 1.00 20.03 ? 408 HOH D O 1 HETATM 7149 O O . HOH Q 7 . ? -12.375 11.918 14.568 1.00 39.86 ? 409 HOH D O 1 HETATM 7150 O O . HOH Q 7 . ? 5.058 -7.696 14.715 1.00 28.75 ? 410 HOH D O 1 HETATM 7151 O O . HOH Q 7 . ? -4.213 4.487 2.829 1.00 27.00 ? 411 HOH D O 1 HETATM 7152 O O . HOH Q 7 . ? -0.984 9.143 29.509 1.00 21.70 ? 412 HOH D O 1 HETATM 7153 O O . HOH Q 7 . ? -9.506 3.232 18.826 1.00 30.57 ? 413 HOH D O 1 HETATM 7154 O O . HOH Q 7 . ? 10.949 1.674 36.188 1.00 14.63 ? 414 HOH D O 1 HETATM 7155 O O . HOH Q 7 . ? 10.656 0.603 20.476 1.00 28.64 ? 415 HOH D O 1 HETATM 7156 O O . HOH Q 7 . ? -8.143 8.571 33.500 1.00 38.61 ? 416 HOH D O 1 HETATM 7157 O O . HOH Q 7 . ? -12.684 9.764 18.350 1.00 39.04 ? 417 HOH D O 1 HETATM 7158 O O . HOH Q 7 . ? -9.580 -3.977 18.823 1.00 34.53 ? 418 HOH D O 1 HETATM 7159 O O . HOH Q 7 . ? -4.496 7.950 32.588 1.00 27.16 ? 419 HOH D O 1 HETATM 7160 O O . HOH Q 7 . ? 0.525 1.045 -1.607 1.00 29.82 ? 420 HOH D O 1 HETATM 7161 O O . HOH Q 7 . ? 16.177 -4.623 50.607 1.00 26.23 ? 421 HOH D O 1 HETATM 7162 O O . HOH Q 7 . ? 15.175 7.448 7.511 1.00 36.34 ? 422 HOH D O 1 HETATM 7163 O O . HOH Q 7 . ? 18.170 -0.782 41.468 1.00 26.91 ? 423 HOH D O 1 HETATM 7164 O O . HOH Q 7 . ? 6.902 -4.685 36.407 1.00 21.89 ? 424 HOH D O 1 HETATM 7165 O O . HOH Q 7 . ? -10.028 23.462 19.522 1.00 33.60 ? 425 HOH D O 1 HETATM 7166 O O . HOH Q 7 . ? 6.045 15.499 17.948 1.00 38.46 ? 426 HOH D O 1 HETATM 7167 O O . HOH Q 7 . ? 14.326 -0.504 23.252 1.00 35.17 ? 427 HOH D O 1 HETATM 7168 O O . HOH Q 7 . ? -2.458 2.388 -0.548 1.00 30.71 ? 428 HOH D O 1 HETATM 7169 O O . HOH Q 7 . ? -6.224 22.054 19.121 1.00 31.65 ? 429 HOH D O 1 HETATM 7170 O O . HOH Q 7 . ? 11.310 -0.738 54.162 1.00 23.00 ? 430 HOH D O 1 HETATM 7171 O O . HOH Q 7 . ? 11.155 9.567 19.705 1.00 32.14 ? 431 HOH D O 1 HETATM 7172 O O . HOH Q 7 . ? -8.033 22.739 30.819 1.00 34.28 ? 432 HOH D O 1 HETATM 7173 O O . HOH Q 7 . ? -2.685 20.035 26.358 1.00 33.61 ? 433 HOH D O 1 HETATM 7174 O O . HOH Q 7 . ? 5.578 -14.537 43.185 1.00 21.63 ? 434 HOH D O 1 HETATM 7175 O O . HOH Q 7 . ? -13.234 7.317 15.727 1.00 33.41 ? 435 HOH D O 1 HETATM 7176 O O . HOH Q 7 . ? -10.567 -0.975 12.885 1.00 15.53 ? 436 HOH D O 1 HETATM 7177 O O . HOH Q 7 . ? 3.392 0.862 3.941 1.00 25.67 ? 437 HOH D O 1 HETATM 7178 O O . HOH Q 7 . ? 2.884 4.968 27.301 1.00 14.82 ? 438 HOH D O 1 HETATM 7179 O O . HOH Q 7 . ? -13.026 12.993 19.286 1.00 37.44 ? 439 HOH D O 1 HETATM 7180 O O . HOH Q 7 . ? 5.701 6.499 32.577 1.00 22.46 ? 440 HOH D O 1 HETATM 7181 O O . HOH Q 7 . ? 10.099 2.657 -1.321 1.00 37.57 ? 441 HOH D O 1 HETATM 7182 O O . HOH Q 7 . ? -5.072 15.180 38.619 1.00 27.55 ? 442 HOH D O 1 HETATM 7183 O O . HOH Q 7 . ? -9.402 0.946 11.457 1.00 22.92 ? 443 HOH D O 1 HETATM 7184 O O . HOH Q 7 . ? 10.055 12.451 1.259 1.00 44.39 ? 444 HOH D O 1 HETATM 7185 O O . HOH Q 7 . ? 15.986 1.052 4.201 1.00 29.94 ? 445 HOH D O 1 HETATM 7186 O O . HOH Q 7 . ? 6.716 11.948 28.807 1.00 34.17 ? 446 HOH D O 1 HETATM 7187 O O . HOH Q 7 . ? -9.683 10.379 30.151 1.00 42.48 ? 447 HOH D O 1 HETATM 7188 O O . HOH Q 7 . ? -11.667 2.428 10.627 1.00 26.04 ? 448 HOH D O 1 HETATM 7189 O O . HOH Q 7 . ? 2.917 15.418 43.969 1.00 31.75 ? 449 HOH D O 1 HETATM 7190 O O . HOH Q 7 . ? 8.805 12.422 25.896 1.00 40.95 ? 450 HOH D O 1 HETATM 7191 O O . HOH Q 7 . ? 2.840 0.756 51.995 1.00 26.50 ? 451 HOH D O 1 HETATM 7192 O O . HOH Q 7 . ? -10.500 5.229 46.635 1.00 32.31 ? 452 HOH D O 1 HETATM 7193 O O . HOH Q 7 . ? 12.311 -5.706 36.857 1.00 29.56 ? 453 HOH D O 1 HETATM 7194 O O . HOH Q 7 . ? -0.008 9.557 49.789 1.00 33.38 ? 454 HOH D O 1 HETATM 7195 O O . HOH Q 7 . ? 1.231 7.753 -2.049 1.00 22.42 ? 455 HOH D O 1 HETATM 7196 O O . HOH Q 7 . ? 2.451 16.117 5.187 1.00 28.37 ? 456 HOH D O 1 HETATM 7197 O O . HOH Q 7 . ? 14.288 1.062 54.011 1.00 36.59 ? 457 HOH D O 1 HETATM 7198 O O . HOH Q 7 . ? 15.034 -6.389 12.048 1.00 40.76 ? 458 HOH D O 1 HETATM 7199 O O . HOH Q 7 . ? 20.292 -6.343 11.245 1.00 45.17 ? 459 HOH D O 1 HETATM 7200 O O . HOH Q 7 . ? -14.129 16.012 26.150 1.00 28.10 ? 460 HOH D O 1 HETATM 7201 O O . HOH Q 7 . ? 12.819 -13.904 43.340 1.00 25.67 ? 461 HOH D O 1 HETATM 7202 O O . HOH Q 7 . ? 13.718 -6.032 14.636 1.00 41.52 ? 462 HOH D O 1 HETATM 7203 O O . HOH Q 7 . ? -1.263 20.060 24.200 1.00 29.12 ? 463 HOH D O 1 HETATM 7204 O O . HOH Q 7 . ? -1.400 7.381 -1.495 1.00 25.54 ? 464 HOH D O 1 HETATM 7205 O O . HOH Q 7 . ? 13.507 10.709 29.662 1.00 41.76 ? 465 HOH D O 1 HETATM 7206 O O . HOH Q 7 . ? 4.832 15.326 4.192 1.00 36.59 ? 466 HOH D O 1 HETATM 7207 O O . HOH Q 7 . ? 8.203 -13.297 35.707 1.00 37.01 ? 467 HOH D O 1 HETATM 7208 O O . HOH Q 7 . ? -7.791 14.675 40.628 1.00 38.91 ? 468 HOH D O 1 HETATM 7209 O O . HOH Q 7 . ? -7.465 13.679 38.250 1.00 28.79 ? 469 HOH D O 1 HETATM 7210 O O . HOH Q 7 . ? 4.736 15.956 16.496 1.00 50.06 ? 470 HOH D O 1 HETATM 7211 O O . HOH Q 7 . ? 11.618 -17.250 46.710 1.00 22.16 ? 471 HOH D O 1 HETATM 7212 O O . HOH Q 7 . ? 8.630 -9.043 35.781 1.00 36.61 ? 472 HOH D O 1 HETATM 7213 O O . HOH Q 7 . ? 10.137 -17.129 44.933 1.00 24.40 ? 473 HOH D O 1 HETATM 7214 O O . HOH Q 7 . ? -0.087 -0.682 35.427 1.00 31.68 ? 474 HOH D O 1 HETATM 7215 O O . HOH Q 7 . ? -1.899 4.418 -1.483 1.00 33.91 ? 475 HOH D O 1 HETATM 7216 O O . HOH Q 7 . ? 5.497 14.007 44.025 1.00 37.99 ? 476 HOH D O 1 HETATM 7217 O O . HOH Q 7 . ? 11.251 -16.351 42.975 1.00 34.18 ? 477 HOH D O 1 HETATM 7218 O O . HOH Q 7 . ? -6.382 23.540 32.936 1.00 39.55 ? 478 HOH D O 1 HETATM 7219 O O . HOH Q 7 . ? 9.328 -1.630 20.908 1.00 38.75 ? 479 HOH D O 1 HETATM 7220 O O . HOH Q 7 . ? -13.603 9.778 15.341 1.00 40.47 ? 480 HOH D O 1 HETATM 7221 O O . HOH Q 7 . ? 8.997 -0.039 56.437 1.00 29.56 ? 481 HOH D O 1 HETATM 7222 O O . HOH Q 7 . ? 9.483 -6.903 36.345 1.00 32.13 ? 482 HOH D O 1 HETATM 7223 O O . HOH R 7 . ? -30.867 -38.922 31.647 1.00 28.05 ? 101 HOH E O 1 HETATM 7224 O O . HOH R 7 . ? -25.135 -24.750 30.468 1.00 29.12 ? 102 HOH E O 1 HETATM 7225 O O . HOH R 7 . ? -24.552 -36.335 37.789 1.00 30.12 ? 103 HOH E O 1 HETATM 7226 O O . HOH R 7 . ? -32.036 -39.108 35.459 1.00 28.95 ? 104 HOH E O 1 HETATM 7227 O O . HOH R 7 . ? -24.639 -35.299 27.771 1.00 34.70 ? 105 HOH E O 1 HETATM 7228 O O . HOH R 7 . ? -31.071 -34.606 36.485 1.00 33.15 ? 106 HOH E O 1 HETATM 7229 O O . HOH S 7 . ? -15.410 -7.498 23.045 1.00 44.00 ? 101 HOH F O 1 HETATM 7230 O O . HOH S 7 . ? -0.190 0.780 28.974 1.00 26.78 ? 102 HOH F O 1 HETATM 7231 O O . HOH S 7 . ? -11.824 -10.288 32.069 1.00 44.61 ? 103 HOH F O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ASP 1 1 1 ASP ASP A . n A 1 2 ILE 2 2 2 ILE ILE A . n A 1 3 LEU 3 3 3 LEU LEU A . n A 1 4 LEU 4 4 4 LEU LEU A . n A 1 5 THR 5 5 5 THR THR A . n A 1 6 GLN 6 6 6 GLN GLN A . n A 1 7 SER 7 7 7 SER SER A . n A 1 8 PRO 8 8 8 PRO PRO A . n A 1 9 VAL 9 9 9 VAL VAL A . n A 1 10 ILE 10 10 10 ILE ILE A . n A 1 11 LEU 11 11 11 LEU LEU A . n A 1 12 SER 12 12 12 SER SER A . n A 1 13 VAL 13 13 13 VAL VAL A . n A 1 14 SER 14 14 14 SER SER A . n A 1 15 PRO 15 15 15 PRO PRO A . n A 1 16 GLY 16 16 16 GLY GLY A . n A 1 17 GLU 17 17 17 GLU GLU A . n A 1 18 ARG 18 18 18 ARG ARG A . n A 1 19 VAL 19 19 19 VAL VAL A . n A 1 20 SER 20 20 20 SER SER A . n A 1 21 PHE 21 21 21 PHE PHE A . n A 1 22 SER 22 22 22 SER SER A . n A 1 23 CYS 23 23 23 CYS CYS A . n A 1 24 ARG 24 24 24 ARG ARG A . n A 1 25 ALA 25 25 25 ALA ALA A . n A 1 26 SER 26 26 26 SER SER A . n A 1 27 GLN 27 27 27 GLN GLN A . n A 1 28 SER 28 28 28 SER SER A . n A 1 29 ILE 29 29 29 ILE ILE A . n A 1 30 GLY 30 30 30 GLY GLY A . n A 1 31 THR 31 31 31 THR THR A . n A 1 32 ASN 32 32 32 ASN ASN A . n A 1 33 ILE 33 33 33 ILE ILE A . n A 1 34 HIS 34 34 34 HIS HIS A . n A 1 35 TRP 35 35 35 TRP TRP A . n A 1 36 TYR 36 36 36 TYR TYR A . n A 1 37 GLN 37 37 37 GLN GLN A . n A 1 38 GLN 38 38 38 GLN GLN A . n A 1 39 ARG 39 39 39 ARG ARG A . n A 1 40 THR 40 40 40 THR THR A . n A 1 41 ASN 41 41 41 ASN ASN A . n A 1 42 GLY 42 42 42 GLY GLY A . n A 1 43 SER 43 43 43 SER SER A . n A 1 44 PRO 44 44 44 PRO PRO A . n A 1 45 ARG 45 45 45 ARG ARG A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 LEU 47 47 47 LEU LEU A . n A 1 48 ILE 48 48 48 ILE ILE A . n A 1 49 LYS 49 49 49 LYS LYS A . n A 1 50 TYR 50 50 50 TYR TYR A . n A 1 51 ALA 51 51 51 ALA ALA A . n A 1 52 SER 52 52 52 SER SER A . n A 1 53 GLU 53 53 53 GLU GLU A . n A 1 54 SER 54 54 54 SER SER A . n A 1 55 ILE 55 55 55 ILE ILE A . n A 1 56 SER 56 56 56 SER SER A . n A 1 57 GLY 57 57 57 GLY GLY A . n A 1 58 ILE 58 58 58 ILE ILE A . n A 1 59 PRO 59 59 59 PRO PRO A . n A 1 60 SER 60 60 60 SER SER A . n A 1 61 ARG 61 61 61 ARG ARG A . n A 1 62 PHE 62 62 62 PHE PHE A . n A 1 63 SER 63 63 63 SER SER A . n A 1 64 GLY 64 64 64 GLY GLY A . n A 1 65 SER 65 65 65 SER SER A . n A 1 66 GLY 66 66 66 GLY GLY A . n A 1 67 SER 67 67 67 SER SER A . n A 1 68 GLY 68 68 68 GLY GLY A . n A 1 69 THR 69 69 69 THR THR A . n A 1 70 ASP 70 70 70 ASP ASP A . n A 1 71 PHE 71 71 71 PHE PHE A . n A 1 72 THR 72 72 72 THR THR A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 SER 74 74 74 SER SER A . n A 1 75 ILE 75 75 75 ILE ILE A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 SER 77 77 77 SER SER A . n A 1 78 VAL 78 78 78 VAL VAL A . n A 1 79 GLU 79 79 79 GLU GLU A . n A 1 80 SER 80 80 80 SER SER A . n A 1 81 GLU 81 81 81 GLU GLU A . n A 1 82 ASP 82 82 82 ASP ASP A . n A 1 83 ILE 83 83 83 ILE ILE A . n A 1 84 ALA 84 84 84 ALA ALA A . n A 1 85 ASP 85 85 85 ASP ASP A . n A 1 86 TYR 86 86 86 TYR TYR A . n A 1 87 TYR 87 87 87 TYR TYR A . n A 1 88 CYS 88 88 88 CYS CYS A . n A 1 89 GLN 89 89 89 GLN GLN A . n A 1 90 GLN 90 90 90 GLN GLN A . n A 1 91 ASN 91 91 91 ASN ASN A . n A 1 92 ASN 92 92 92 ASN ASN A . n A 1 93 ASN 93 93 93 ASN ASN A . n A 1 94 TRP 94 94 94 TRP TRP A . n A 1 95 PRO 95 95 95 PRO PRO A . n A 1 96 THR 96 96 96 THR THR A . n A 1 97 THR 97 97 97 THR THR A . n A 1 98 PHE 98 98 98 PHE PHE A . n A 1 99 GLY 99 99 99 GLY GLY A . n A 1 100 ALA 100 100 100 ALA ALA A . n A 1 101 GLY 101 101 101 GLY GLY A . n A 1 102 THR 102 102 102 THR THR A . n A 1 103 LYS 103 103 103 LYS LYS A . n A 1 104 LEU 104 104 104 LEU LEU A . n A 1 105 GLU 105 105 105 GLU GLU A . n A 1 106 LEU 106 106 106 LEU LEU A . n A 1 107 LYS 107 107 107 LYS LYS A . n A 1 108 ARG 108 108 108 ARG ARG A . n A 1 109 THR 109 109 109 THR THR A . n A 1 110 VAL 110 110 110 VAL VAL A . n A 1 111 ALA 111 111 111 ALA ALA A . n A 1 112 ALA 112 112 112 ALA ALA A . n A 1 113 PRO 113 113 113 PRO PRO A . n A 1 114 SER 114 114 114 SER SER A . n A 1 115 VAL 115 115 115 VAL VAL A . n A 1 116 PHE 116 116 116 PHE PHE A . n A 1 117 ILE 117 117 117 ILE ILE A . n A 1 118 PHE 118 118 118 PHE PHE A . n A 1 119 PRO 119 119 119 PRO PRO A . n A 1 120 PRO 120 120 120 PRO PRO A . n A 1 121 SER 121 121 121 SER SER A . n A 1 122 ASP 122 122 122 ASP ASP A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 GLN 124 124 124 GLN GLN A . n A 1 125 LEU 125 125 125 LEU LEU A . n A 1 126 LYS 126 126 126 LYS LYS A . n A 1 127 SER 127 127 127 SER SER A . n A 1 128 GLY 128 128 128 GLY GLY A . n A 1 129 THR 129 129 129 THR THR A . n A 1 130 ALA 130 130 130 ALA ALA A . n A 1 131 SER 131 131 131 SER SER A . n A 1 132 VAL 132 132 132 VAL VAL A . n A 1 133 VAL 133 133 133 VAL VAL A . n A 1 134 CYS 134 134 134 CYS CYS A . n A 1 135 LEU 135 135 135 LEU LEU A . n A 1 136 LEU 136 136 136 LEU LEU A . n A 1 137 ASN 137 137 137 ASN ASN A . n A 1 138 ASN 138 138 138 ASN ASN A . n A 1 139 PHE 139 139 139 PHE PHE A . n A 1 140 TYR 140 140 140 TYR TYR A . n A 1 141 PRO 141 141 141 PRO PRO A . n A 1 142 ARG 142 142 142 ARG ARG A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 ALA 144 144 144 ALA ALA A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 VAL 146 146 146 VAL VAL A . n A 1 147 GLN 147 147 147 GLN GLN A . n A 1 148 TRP 148 148 148 TRP TRP A . n A 1 149 LYS 149 149 149 LYS LYS A . n A 1 150 VAL 150 150 150 VAL VAL A . n A 1 151 ASP 151 151 151 ASP ASP A . n A 1 152 ASN 152 152 152 ASN ASN A . n A 1 153 ALA 153 153 153 ALA ALA A . n A 1 154 LEU 154 154 154 LEU LEU A . n A 1 155 GLN 155 155 155 GLN GLN A . n A 1 156 SER 156 156 156 SER SER A . n A 1 157 GLY 157 157 157 GLY GLY A . n A 1 158 ASN 158 158 158 ASN ASN A . n A 1 159 SER 159 159 159 SER SER A . n A 1 160 GLN 160 160 160 GLN GLN A . n A 1 161 GLU 161 161 161 GLU GLU A . n A 1 162 SER 162 162 162 SER SER A . n A 1 163 VAL 163 163 163 VAL VAL A . n A 1 164 THR 164 164 164 THR THR A . n A 1 165 GLU 165 165 165 GLU GLU A . n A 1 166 GLN 166 166 166 GLN GLN A . n A 1 167 ASP 167 167 167 ASP ASP A . n A 1 168 SER 168 168 168 SER SER A . n A 1 169 LYS 169 169 169 LYS LYS A . n A 1 170 ASP 170 170 170 ASP ASP A . n A 1 171 SER 171 171 171 SER SER A . n A 1 172 THR 172 172 172 THR THR A . n A 1 173 TYR 173 173 173 TYR TYR A . n A 1 174 SER 174 174 174 SER SER A . n A 1 175 LEU 175 175 175 LEU LEU A . n A 1 176 SER 176 176 176 SER SER A . n A 1 177 SER 177 177 177 SER SER A . n A 1 178 THR 178 178 178 THR THR A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 THR 180 180 180 THR THR A . n A 1 181 LEU 181 181 181 LEU LEU A . n A 1 182 SER 182 182 182 SER SER A . n A 1 183 LYS 183 183 183 LYS LYS A . n A 1 184 ALA 184 184 184 ALA ALA A . n A 1 185 ASP 185 185 185 ASP ASP A . n A 1 186 TYR 186 186 186 TYR TYR A . n A 1 187 GLU 187 187 187 GLU GLU A . n A 1 188 LYS 188 188 188 LYS LYS A . n A 1 189 HIS 189 189 189 HIS HIS A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 VAL 191 191 191 VAL VAL A . n A 1 192 TYR 192 192 192 TYR TYR A . n A 1 193 ALA 193 193 193 ALA ALA A . n A 1 194 CYS 194 194 194 CYS CYS A . n A 1 195 GLU 195 195 195 GLU GLU A . n A 1 196 VAL 196 196 196 VAL VAL A . n A 1 197 THR 197 197 197 THR THR A . n A 1 198 HIS 198 198 198 HIS HIS A . n A 1 199 GLN 199 199 199 GLN GLN A . n A 1 200 GLY 200 200 200 GLY GLY A . n A 1 201 LEU 201 201 201 LEU LEU A . n A 1 202 SER 202 202 202 SER SER A . n A 1 203 SER 203 203 203 SER SER A . n A 1 204 PRO 204 204 204 PRO PRO A . n A 1 205 VAL 205 205 205 VAL VAL A . n A 1 206 THR 206 206 206 THR THR A . n A 1 207 LYS 207 207 207 LYS LYS A . n A 1 208 SER 208 208 208 SER SER A . n A 1 209 PHE 209 209 209 PHE PHE A . n A 1 210 ASN 210 210 210 ASN ASN A . n A 1 211 ARG 211 211 211 ARG ARG A . n A 1 212 GLY 212 212 212 GLY GLY A . n A 1 213 ALA 213 213 ? ? ? A . n B 2 1 GLN 1 1 1 GLN GLN B . n B 2 2 VAL 2 2 2 VAL VAL B . n B 2 3 GLN 3 3 3 GLN GLN B . n B 2 4 LEU 4 4 4 LEU LEU B . n B 2 5 LYS 5 5 5 LYS LYS B . n B 2 6 GLN 6 6 6 GLN GLN B . n B 2 7 SER 7 7 7 SER SER B . n B 2 8 GLY 8 8 8 GLY GLY B . n B 2 9 PRO 9 9 9 PRO PRO B . n B 2 10 GLY 10 10 10 GLY GLY B . n B 2 11 LEU 11 11 11 LEU LEU B . n B 2 12 VAL 12 12 12 VAL VAL B . n B 2 13 GLN 13 13 13 GLN GLN B . n B 2 14 PRO 14 14 14 PRO PRO B . n B 2 15 SER 15 15 15 SER SER B . n B 2 16 GLN 16 16 16 GLN GLN B . n B 2 17 SER 17 17 17 SER SER B . n B 2 18 LEU 18 18 18 LEU LEU B . n B 2 19 SER 19 19 19 SER SER B . n B 2 20 ILE 20 20 20 ILE ILE B . n B 2 21 THR 21 21 21 THR THR B . n B 2 22 CYS 22 22 22 CYS CYS B . n B 2 23 THR 23 23 23 THR THR B . n B 2 24 VAL 24 24 24 VAL VAL B . n B 2 25 SER 25 25 25 SER SER B . n B 2 26 GLY 26 26 26 GLY GLY B . n B 2 27 PHE 27 27 27 PHE PHE B . n B 2 28 SER 28 28 28 SER SER B . n B 2 29 LEU 29 29 29 LEU LEU B . n B 2 30 THR 30 30 30 THR THR B . n B 2 31 ASN 31 31 31 ASN ASN B . n B 2 32 TYR 32 32 32 TYR TYR B . n B 2 33 GLY 33 33 33 GLY GLY B . n B 2 34 VAL 34 34 34 VAL VAL B . n B 2 35 HIS 35 35 35 HIS HIS B . n B 2 36 TRP 36 36 36 TRP TRP B . n B 2 37 VAL 37 37 37 VAL VAL B . n B 2 38 ARG 38 38 38 ARG ARG B . n B 2 39 GLN 39 39 39 GLN GLN B . n B 2 40 SER 40 40 40 SER SER B . n B 2 41 PRO 41 41 41 PRO PRO B . n B 2 42 GLY 42 42 42 GLY GLY B . n B 2 43 LYS 43 43 43 LYS LYS B . n B 2 44 GLY 44 44 44 GLY GLY B . n B 2 45 LEU 45 45 45 LEU LEU B . n B 2 46 GLU 46 46 46 GLU GLU B . n B 2 47 TRP 47 47 47 TRP TRP B . n B 2 48 LEU 48 48 48 LEU LEU B . n B 2 49 GLY 49 49 49 GLY GLY B . n B 2 50 VAL 50 50 50 VAL VAL B . n B 2 51 ILE 51 51 51 ILE ILE B . n B 2 52 TRP 52 52 52 TRP TRP B . n B 2 53 SER 53 53 53 SER SER B . n B 2 54 GLY 54 54 54 GLY GLY B . n B 2 55 GLY 55 55 55 GLY GLY B . n B 2 56 ASN 56 56 56 ASN ASN B . n B 2 57 THR 57 57 57 THR THR B . n B 2 58 ASP 58 58 58 ASP ASP B . n B 2 59 TYR 59 59 59 TYR TYR B . n B 2 60 ASN 60 60 60 ASN ASN B . n B 2 61 THR 61 61 61 THR THR B . n B 2 62 PRO 62 62 62 PRO PRO B . n B 2 63 PHE 63 63 63 PHE PHE B . n B 2 64 THR 64 64 64 THR THR B . n B 2 65 SER 65 65 65 SER SER B . n B 2 66 ARG 66 66 66 ARG ARG B . n B 2 67 LEU 67 67 67 LEU LEU B . n B 2 68 SER 68 68 68 SER SER B . n B 2 69 ILE 69 69 69 ILE ILE B . n B 2 70 ASN 70 70 70 ASN ASN B . n B 2 71 LYS 71 71 71 LYS LYS B . n B 2 72 ASP 72 72 72 ASP ASP B . n B 2 73 ASN 73 73 73 ASN ASN B . n B 2 74 SER 74 74 74 SER SER B . n B 2 75 LYS 75 75 75 LYS LYS B . n B 2 76 SER 76 76 76 SER SER B . n B 2 77 GLN 77 77 77 GLN GLN B . n B 2 78 VAL 78 78 78 VAL VAL B . n B 2 79 PHE 79 79 79 PHE PHE B . n B 2 80 PHE 80 80 80 PHE PHE B . n B 2 81 LYS 81 81 81 LYS LYS B . n B 2 82 MET 82 82 82 MET MET B . n B 2 83 ASN 83 83 83 ASN ASN B . n B 2 84 SER 84 84 84 SER SER B . n B 2 85 LEU 85 85 85 LEU LEU B . n B 2 86 GLN 86 86 86 GLN GLN B . n B 2 87 SER 87 87 87 SER SER B . n B 2 88 ASN 88 88 88 ASN ASN B . n B 2 89 ASP 89 89 89 ASP ASP B . n B 2 90 THR 90 90 90 THR THR B . n B 2 91 ALA 91 91 91 ALA ALA B . n B 2 92 ILE 92 92 92 ILE ILE B . n B 2 93 TYR 93 93 93 TYR TYR B . n B 2 94 TYR 94 94 94 TYR TYR B . n B 2 95 CYS 95 95 95 CYS CYS B . n B 2 96 ALA 96 96 96 ALA ALA B . n B 2 97 ARG 97 97 97 ARG ARG B . n B 2 98 ALA 98 98 98 ALA ALA B . n B 2 99 LEU 99 99 99 LEU LEU B . n B 2 100 THR 100 100 100 THR THR B . n B 2 101 TYR 101 101 101 TYR TYR B . n B 2 102 TYR 102 102 102 TYR TYR B . n B 2 103 ASP 103 103 103 ASP ASP B . n B 2 104 TYR 104 104 104 TYR TYR B . n B 2 105 GLU 105 105 105 GLU GLU B . n B 2 106 PHE 106 106 106 PHE PHE B . n B 2 107 ALA 107 107 107 ALA ALA B . n B 2 108 TYR 108 108 108 TYR TYR B . n B 2 109 TRP 109 109 109 TRP TRP B . n B 2 110 GLY 110 110 110 GLY GLY B . n B 2 111 GLN 111 111 111 GLN GLN B . n B 2 112 GLY 112 112 112 GLY GLY B . n B 2 113 THR 113 113 113 THR THR B . n B 2 114 LEU 114 114 114 LEU LEU B . n B 2 115 VAL 115 115 115 VAL VAL B . n B 2 116 THR 116 116 116 THR THR B . n B 2 117 VAL 117 117 117 VAL VAL B . n B 2 118 SER 118 118 118 SER SER B . n B 2 119 ALA 119 119 119 ALA ALA B . n B 2 120 ALA 120 120 120 ALA ALA B . n B 2 121 SER 121 121 121 SER SER B . n B 2 122 THR 122 122 122 THR THR B . n B 2 123 LYS 123 123 123 LYS LYS B . n B 2 124 GLY 124 124 124 GLY GLY B . n B 2 125 PRO 125 125 125 PRO PRO B . n B 2 126 SER 126 126 126 SER SER B . n B 2 127 VAL 127 127 127 VAL VAL B . n B 2 128 PHE 128 128 128 PHE PHE B . n B 2 129 PRO 129 129 129 PRO PRO B . n B 2 130 LEU 130 130 130 LEU LEU B . n B 2 131 ALA 131 131 131 ALA ALA B . n B 2 132 PRO 132 132 132 PRO PRO B . n B 2 133 SER 133 133 133 SER SER B . n B 2 134 SER 134 134 134 SER SER B . n B 2 135 LYS 135 135 135 LYS LYS B . n B 2 136 SER 136 136 136 SER SER B . n B 2 137 THR 137 137 137 THR THR B . n B 2 138 SER 138 138 138 SER SER B . n B 2 139 GLY 139 139 139 GLY GLY B . n B 2 140 GLY 140 140 140 GLY GLY B . n B 2 141 THR 141 141 141 THR THR B . n B 2 142 ALA 142 142 142 ALA ALA B . n B 2 143 ALA 143 143 143 ALA ALA B . n B 2 144 LEU 144 144 144 LEU LEU B . n B 2 145 GLY 145 145 145 GLY GLY B . n B 2 146 CYS 146 146 146 CYS CYS B . n B 2 147 LEU 147 147 147 LEU LEU B . n B 2 148 VAL 148 148 148 VAL VAL B . n B 2 149 LYS 149 149 149 LYS LYS B . n B 2 150 ASP 150 150 150 ASP ASP B . n B 2 151 TYR 151 151 151 TYR TYR B . n B 2 152 PHE 152 152 152 PHE PHE B . n B 2 153 PRO 153 153 153 PRO PRO B . n B 2 154 GLU 154 154 154 GLU GLU B . n B 2 155 PRO 155 155 155 PRO PRO B . n B 2 156 VAL 156 156 156 VAL VAL B . n B 2 157 THR 157 157 157 THR THR B . n B 2 158 VAL 158 158 158 VAL VAL B . n B 2 159 SER 159 159 159 SER SER B . n B 2 160 TRP 160 160 160 TRP TRP B . n B 2 161 ASN 161 161 161 ASN ASN B . n B 2 162 SER 162 162 162 SER SER B . n B 2 163 GLY 163 163 163 GLY GLY B . n B 2 164 ALA 164 164 164 ALA ALA B . n B 2 165 LEU 165 165 165 LEU LEU B . n B 2 166 THR 166 166 166 THR THR B . n B 2 167 SER 167 167 167 SER SER B . n B 2 168 GLY 168 168 168 GLY GLY B . n B 2 169 VAL 169 169 169 VAL VAL B . n B 2 170 HIS 170 170 170 HIS HIS B . n B 2 171 THR 171 171 171 THR THR B . n B 2 172 PHE 172 172 172 PHE PHE B . n B 2 173 PRO 173 173 173 PRO PRO B . n B 2 174 ALA 174 174 174 ALA ALA B . n B 2 175 VAL 175 175 175 VAL VAL B . n B 2 176 LEU 176 176 176 LEU LEU B . n B 2 177 GLN 177 177 177 GLN GLN B . n B 2 178 SER 178 178 178 SER SER B . n B 2 179 SER 179 179 179 SER SER B . n B 2 180 GLY 180 180 180 GLY GLY B . n B 2 181 LEU 181 181 181 LEU LEU B . n B 2 182 TYR 182 182 182 TYR TYR B . n B 2 183 SER 183 183 183 SER SER B . n B 2 184 LEU 184 184 184 LEU LEU B . n B 2 185 SER 185 185 185 SER SER B . n B 2 186 SER 186 186 186 SER SER B . n B 2 187 VAL 187 187 187 VAL VAL B . n B 2 188 VAL 188 188 188 VAL VAL B . n B 2 189 THR 189 189 189 THR THR B . n B 2 190 VAL 190 190 190 VAL VAL B . n B 2 191 PRO 191 191 191 PRO PRO B . n B 2 192 SER 192 192 192 SER SER B . n B 2 193 SER 193 193 193 SER SER B . n B 2 194 SER 194 194 194 SER SER B . n B 2 195 LEU 195 195 195 LEU LEU B . n B 2 196 GLY 196 196 196 GLY GLY B . n B 2 197 THR 197 197 197 THR THR B . n B 2 198 GLN 198 198 198 GLN GLN B . n B 2 199 THR 199 199 199 THR THR B . n B 2 200 TYR 200 200 200 TYR TYR B . n B 2 201 ILE 201 201 201 ILE ILE B . n B 2 202 CYS 202 202 202 CYS CYS B . n B 2 203 ASN 203 203 203 ASN ASN B . n B 2 204 VAL 204 204 204 VAL VAL B . n B 2 205 ASN 205 205 205 ASN ASN B . n B 2 206 HIS 206 206 206 HIS HIS B . n B 2 207 LYS 207 207 207 LYS LYS B . n B 2 208 PRO 208 208 208 PRO PRO B . n B 2 209 SER 209 209 209 SER SER B . n B 2 210 ASN 210 210 210 ASN ASN B . n B 2 211 THR 211 211 211 THR THR B . n B 2 212 LYS 212 212 212 LYS LYS B . n B 2 213 VAL 213 213 213 VAL VAL B . n B 2 214 ASP 214 214 214 ASP ASP B . n B 2 215 LYS 215 215 215 LYS LYS B . n B 2 216 ARG 216 216 216 ARG ARG B . n B 2 217 VAL 217 217 217 VAL VAL B . n B 2 218 GLU 218 218 218 GLU GLU B . n B 2 219 PRO 219 219 219 PRO PRO B . n B 2 220 LYS 220 220 220 LYS LYS B . n C 1 1 ASP 1 1 1 ASP ASP C . n C 1 2 ILE 2 2 2 ILE ILE C . n C 1 3 LEU 3 3 3 LEU LEU C . n C 1 4 LEU 4 4 4 LEU LEU C . n C 1 5 THR 5 5 5 THR THR C . n C 1 6 GLN 6 6 6 GLN GLN C . n C 1 7 SER 7 7 7 SER SER C . n C 1 8 PRO 8 8 8 PRO PRO C . n C 1 9 VAL 9 9 9 VAL VAL C . n C 1 10 ILE 10 10 10 ILE ILE C . n C 1 11 LEU 11 11 11 LEU LEU C . n C 1 12 SER 12 12 12 SER SER C . n C 1 13 VAL 13 13 13 VAL VAL C . n C 1 14 SER 14 14 14 SER SER C . n C 1 15 PRO 15 15 15 PRO PRO C . n C 1 16 GLY 16 16 16 GLY GLY C . n C 1 17 GLU 17 17 17 GLU GLU C . n C 1 18 ARG 18 18 18 ARG ARG C . n C 1 19 VAL 19 19 19 VAL VAL C . n C 1 20 SER 20 20 20 SER SER C . n C 1 21 PHE 21 21 21 PHE PHE C . n C 1 22 SER 22 22 22 SER SER C . n C 1 23 CYS 23 23 23 CYS CYS C . n C 1 24 ARG 24 24 24 ARG ARG C . n C 1 25 ALA 25 25 25 ALA ALA C . n C 1 26 SER 26 26 26 SER SER C . n C 1 27 GLN 27 27 27 GLN GLN C . n C 1 28 SER 28 28 28 SER SER C . n C 1 29 ILE 29 29 29 ILE ILE C . n C 1 30 GLY 30 30 30 GLY GLY C . n C 1 31 THR 31 31 31 THR THR C . n C 1 32 ASN 32 32 32 ASN ASN C . n C 1 33 ILE 33 33 33 ILE ILE C . n C 1 34 HIS 34 34 34 HIS HIS C . n C 1 35 TRP 35 35 35 TRP TRP C . n C 1 36 TYR 36 36 36 TYR TYR C . n C 1 37 GLN 37 37 37 GLN GLN C . n C 1 38 GLN 38 38 38 GLN GLN C . n C 1 39 ARG 39 39 39 ARG ARG C . n C 1 40 THR 40 40 40 THR THR C . n C 1 41 ASN 41 41 41 ASN ASN C . n C 1 42 GLY 42 42 42 GLY GLY C . n C 1 43 SER 43 43 43 SER SER C . n C 1 44 PRO 44 44 44 PRO PRO C . n C 1 45 ARG 45 45 45 ARG ARG C . n C 1 46 LEU 46 46 46 LEU LEU C . n C 1 47 LEU 47 47 47 LEU LEU C . n C 1 48 ILE 48 48 48 ILE ILE C . n C 1 49 LYS 49 49 49 LYS LYS C . n C 1 50 TYR 50 50 50 TYR TYR C . n C 1 51 ALA 51 51 51 ALA ALA C . n C 1 52 SER 52 52 52 SER SER C . n C 1 53 GLU 53 53 53 GLU GLU C . n C 1 54 SER 54 54 54 SER SER C . n C 1 55 ILE 55 55 55 ILE ILE C . n C 1 56 SER 56 56 56 SER SER C . n C 1 57 GLY 57 57 57 GLY GLY C . n C 1 58 ILE 58 58 58 ILE ILE C . n C 1 59 PRO 59 59 59 PRO PRO C . n C 1 60 SER 60 60 60 SER SER C . n C 1 61 ARG 61 61 61 ARG ARG C . n C 1 62 PHE 62 62 62 PHE PHE C . n C 1 63 SER 63 63 63 SER SER C . n C 1 64 GLY 64 64 64 GLY GLY C . n C 1 65 SER 65 65 65 SER SER C . n C 1 66 GLY 66 66 66 GLY GLY C . n C 1 67 SER 67 67 67 SER SER C . n C 1 68 GLY 68 68 68 GLY GLY C . n C 1 69 THR 69 69 69 THR THR C . n C 1 70 ASP 70 70 70 ASP ASP C . n C 1 71 PHE 71 71 71 PHE PHE C . n C 1 72 THR 72 72 72 THR THR C . n C 1 73 LEU 73 73 73 LEU LEU C . n C 1 74 SER 74 74 74 SER SER C . n C 1 75 ILE 75 75 75 ILE ILE C . n C 1 76 ASN 76 76 76 ASN ASN C . n C 1 77 SER 77 77 77 SER SER C . n C 1 78 VAL 78 78 78 VAL VAL C . n C 1 79 GLU 79 79 79 GLU GLU C . n C 1 80 SER 80 80 80 SER SER C . n C 1 81 GLU 81 81 81 GLU GLU C . n C 1 82 ASP 82 82 82 ASP ASP C . n C 1 83 ILE 83 83 83 ILE ILE C . n C 1 84 ALA 84 84 84 ALA ALA C . n C 1 85 ASP 85 85 85 ASP ASP C . n C 1 86 TYR 86 86 86 TYR TYR C . n C 1 87 TYR 87 87 87 TYR TYR C . n C 1 88 CYS 88 88 88 CYS CYS C . n C 1 89 GLN 89 89 89 GLN GLN C . n C 1 90 GLN 90 90 90 GLN GLN C . n C 1 91 ASN 91 91 91 ASN ASN C . n C 1 92 ASN 92 92 92 ASN ASN C . n C 1 93 ASN 93 93 93 ASN ASN C . n C 1 94 TRP 94 94 94 TRP TRP C . n C 1 95 PRO 95 95 95 PRO PRO C . n C 1 96 THR 96 96 96 THR THR C . n C 1 97 THR 97 97 97 THR THR C . n C 1 98 PHE 98 98 98 PHE PHE C . n C 1 99 GLY 99 99 99 GLY GLY C . n C 1 100 ALA 100 100 100 ALA ALA C . n C 1 101 GLY 101 101 101 GLY GLY C . n C 1 102 THR 102 102 102 THR THR C . n C 1 103 LYS 103 103 103 LYS LYS C . n C 1 104 LEU 104 104 104 LEU LEU C . n C 1 105 GLU 105 105 105 GLU GLU C . n C 1 106 LEU 106 106 106 LEU LEU C . n C 1 107 LYS 107 107 107 LYS LYS C . n C 1 108 ARG 108 108 108 ARG ARG C . n C 1 109 THR 109 109 109 THR THR C . n C 1 110 VAL 110 110 110 VAL VAL C . n C 1 111 ALA 111 111 111 ALA ALA C . n C 1 112 ALA 112 112 112 ALA ALA C . n C 1 113 PRO 113 113 113 PRO PRO C . n C 1 114 SER 114 114 114 SER SER C . n C 1 115 VAL 115 115 115 VAL VAL C . n C 1 116 PHE 116 116 116 PHE PHE C . n C 1 117 ILE 117 117 117 ILE ILE C . n C 1 118 PHE 118 118 118 PHE PHE C . n C 1 119 PRO 119 119 119 PRO PRO C . n C 1 120 PRO 120 120 120 PRO PRO C . n C 1 121 SER 121 121 121 SER SER C . n C 1 122 ASP 122 122 122 ASP ASP C . n C 1 123 GLU 123 123 123 GLU GLU C . n C 1 124 GLN 124 124 124 GLN GLN C . n C 1 125 LEU 125 125 125 LEU LEU C . n C 1 126 LYS 126 126 126 LYS LYS C . n C 1 127 SER 127 127 127 SER SER C . n C 1 128 GLY 128 128 128 GLY GLY C . n C 1 129 THR 129 129 129 THR THR C . n C 1 130 ALA 130 130 130 ALA ALA C . n C 1 131 SER 131 131 131 SER SER C . n C 1 132 VAL 132 132 132 VAL VAL C . n C 1 133 VAL 133 133 133 VAL VAL C . n C 1 134 CYS 134 134 134 CYS CYS C . n C 1 135 LEU 135 135 135 LEU LEU C . n C 1 136 LEU 136 136 136 LEU LEU C . n C 1 137 ASN 137 137 137 ASN ASN C . n C 1 138 ASN 138 138 138 ASN ASN C . n C 1 139 PHE 139 139 139 PHE PHE C . n C 1 140 TYR 140 140 140 TYR TYR C . n C 1 141 PRO 141 141 141 PRO PRO C . n C 1 142 ARG 142 142 142 ARG ARG C . n C 1 143 GLU 143 143 143 GLU GLU C . n C 1 144 ALA 144 144 144 ALA ALA C . n C 1 145 LYS 145 145 145 LYS LYS C . n C 1 146 VAL 146 146 146 VAL VAL C . n C 1 147 GLN 147 147 147 GLN GLN C . n C 1 148 TRP 148 148 148 TRP TRP C . n C 1 149 LYS 149 149 149 LYS LYS C . n C 1 150 VAL 150 150 150 VAL VAL C . n C 1 151 ASP 151 151 151 ASP ASP C . n C 1 152 ASN 152 152 152 ASN ASN C . n C 1 153 ALA 153 153 153 ALA ALA C . n C 1 154 LEU 154 154 154 LEU LEU C . n C 1 155 GLN 155 155 155 GLN GLN C . n C 1 156 SER 156 156 156 SER SER C . n C 1 157 GLY 157 157 157 GLY GLY C . n C 1 158 ASN 158 158 158 ASN ASN C . n C 1 159 SER 159 159 159 SER SER C . n C 1 160 GLN 160 160 160 GLN GLN C . n C 1 161 GLU 161 161 161 GLU GLU C . n C 1 162 SER 162 162 162 SER SER C . n C 1 163 VAL 163 163 163 VAL VAL C . n C 1 164 THR 164 164 164 THR THR C . n C 1 165 GLU 165 165 165 GLU GLU C . n C 1 166 GLN 166 166 166 GLN GLN C . n C 1 167 ASP 167 167 167 ASP ASP C . n C 1 168 SER 168 168 168 SER SER C . n C 1 169 LYS 169 169 169 LYS LYS C . n C 1 170 ASP 170 170 170 ASP ASP C . n C 1 171 SER 171 171 171 SER SER C . n C 1 172 THR 172 172 172 THR THR C . n C 1 173 TYR 173 173 173 TYR TYR C . n C 1 174 SER 174 174 174 SER SER C . n C 1 175 LEU 175 175 175 LEU LEU C . n C 1 176 SER 176 176 176 SER SER C . n C 1 177 SER 177 177 177 SER SER C . n C 1 178 THR 178 178 178 THR THR C . n C 1 179 LEU 179 179 179 LEU LEU C . n C 1 180 THR 180 180 180 THR THR C . n C 1 181 LEU 181 181 181 LEU LEU C . n C 1 182 SER 182 182 182 SER SER C . n C 1 183 LYS 183 183 183 LYS LYS C . n C 1 184 ALA 184 184 184 ALA ALA C . n C 1 185 ASP 185 185 185 ASP ASP C . n C 1 186 TYR 186 186 186 TYR TYR C . n C 1 187 GLU 187 187 187 GLU GLU C . n C 1 188 LYS 188 188 188 LYS LYS C . n C 1 189 HIS 189 189 189 HIS HIS C . n C 1 190 LYS 190 190 190 LYS LYS C . n C 1 191 VAL 191 191 191 VAL VAL C . n C 1 192 TYR 192 192 192 TYR TYR C . n C 1 193 ALA 193 193 193 ALA ALA C . n C 1 194 CYS 194 194 194 CYS CYS C . n C 1 195 GLU 195 195 195 GLU GLU C . n C 1 196 VAL 196 196 196 VAL VAL C . n C 1 197 THR 197 197 197 THR THR C . n C 1 198 HIS 198 198 198 HIS HIS C . n C 1 199 GLN 199 199 199 GLN GLN C . n C 1 200 GLY 200 200 200 GLY GLY C . n C 1 201 LEU 201 201 201 LEU LEU C . n C 1 202 SER 202 202 202 SER SER C . n C 1 203 SER 203 203 203 SER SER C . n C 1 204 PRO 204 204 204 PRO PRO C . n C 1 205 VAL 205 205 205 VAL VAL C . n C 1 206 THR 206 206 206 THR THR C . n C 1 207 LYS 207 207 207 LYS LYS C . n C 1 208 SER 208 208 208 SER SER C . n C 1 209 PHE 209 209 209 PHE PHE C . n C 1 210 ASN 210 210 210 ASN ASN C . n C 1 211 ARG 211 211 211 ARG ARG C . n C 1 212 GLY 212 212 212 GLY GLY C . n C 1 213 ALA 213 213 213 ALA ALA C . n D 2 1 GLN 1 1 1 GLN GLN D . n D 2 2 VAL 2 2 2 VAL VAL D . n D 2 3 GLN 3 3 3 GLN GLN D . n D 2 4 LEU 4 4 4 LEU LEU D . n D 2 5 LYS 5 5 5 LYS LYS D . n D 2 6 GLN 6 6 6 GLN GLN D . n D 2 7 SER 7 7 7 SER SER D . n D 2 8 GLY 8 8 8 GLY GLY D . n D 2 9 PRO 9 9 9 PRO PRO D . n D 2 10 GLY 10 10 10 GLY GLY D . n D 2 11 LEU 11 11 11 LEU LEU D . n D 2 12 VAL 12 12 12 VAL VAL D . n D 2 13 GLN 13 13 13 GLN GLN D . n D 2 14 PRO 14 14 14 PRO PRO D . n D 2 15 SER 15 15 15 SER SER D . n D 2 16 GLN 16 16 16 GLN GLN D . n D 2 17 SER 17 17 17 SER SER D . n D 2 18 LEU 18 18 18 LEU LEU D . n D 2 19 SER 19 19 19 SER SER D . n D 2 20 ILE 20 20 20 ILE ILE D . n D 2 21 THR 21 21 21 THR THR D . n D 2 22 CYS 22 22 22 CYS CYS D . n D 2 23 THR 23 23 23 THR THR D . n D 2 24 VAL 24 24 24 VAL VAL D . n D 2 25 SER 25 25 25 SER SER D . n D 2 26 GLY 26 26 26 GLY GLY D . n D 2 27 PHE 27 27 27 PHE PHE D . n D 2 28 SER 28 28 28 SER SER D . n D 2 29 LEU 29 29 29 LEU LEU D . n D 2 30 THR 30 30 30 THR THR D . n D 2 31 ASN 31 31 31 ASN ASN D . n D 2 32 TYR 32 32 32 TYR TYR D . n D 2 33 GLY 33 33 33 GLY GLY D . n D 2 34 VAL 34 34 34 VAL VAL D . n D 2 35 HIS 35 35 35 HIS HIS D . n D 2 36 TRP 36 36 36 TRP TRP D . n D 2 37 VAL 37 37 37 VAL VAL D . n D 2 38 ARG 38 38 38 ARG ARG D . n D 2 39 GLN 39 39 39 GLN GLN D . n D 2 40 SER 40 40 40 SER SER D . n D 2 41 PRO 41 41 41 PRO PRO D . n D 2 42 GLY 42 42 42 GLY GLY D . n D 2 43 LYS 43 43 43 LYS LYS D . n D 2 44 GLY 44 44 44 GLY GLY D . n D 2 45 LEU 45 45 45 LEU LEU D . n D 2 46 GLU 46 46 46 GLU GLU D . n D 2 47 TRP 47 47 47 TRP TRP D . n D 2 48 LEU 48 48 48 LEU LEU D . n D 2 49 GLY 49 49 49 GLY GLY D . n D 2 50 VAL 50 50 50 VAL VAL D . n D 2 51 ILE 51 51 51 ILE ILE D . n D 2 52 TRP 52 52 52 TRP TRP D . n D 2 53 SER 53 53 53 SER SER D . n D 2 54 GLY 54 54 54 GLY GLY D . n D 2 55 GLY 55 55 55 GLY GLY D . n D 2 56 ASN 56 56 56 ASN ASN D . n D 2 57 THR 57 57 57 THR THR D . n D 2 58 ASP 58 58 58 ASP ASP D . n D 2 59 TYR 59 59 59 TYR TYR D . n D 2 60 ASN 60 60 60 ASN ASN D . n D 2 61 THR 61 61 61 THR THR D . n D 2 62 PRO 62 62 62 PRO PRO D . n D 2 63 PHE 63 63 63 PHE PHE D . n D 2 64 THR 64 64 64 THR THR D . n D 2 65 SER 65 65 65 SER SER D . n D 2 66 ARG 66 66 66 ARG ARG D . n D 2 67 LEU 67 67 67 LEU LEU D . n D 2 68 SER 68 68 68 SER SER D . n D 2 69 ILE 69 69 69 ILE ILE D . n D 2 70 ASN 70 70 70 ASN ASN D . n D 2 71 LYS 71 71 71 LYS LYS D . n D 2 72 ASP 72 72 72 ASP ASP D . n D 2 73 ASN 73 73 73 ASN ASN D . n D 2 74 SER 74 74 74 SER SER D . n D 2 75 LYS 75 75 75 LYS LYS D . n D 2 76 SER 76 76 76 SER SER D . n D 2 77 GLN 77 77 77 GLN GLN D . n D 2 78 VAL 78 78 78 VAL VAL D . n D 2 79 PHE 79 79 79 PHE PHE D . n D 2 80 PHE 80 80 80 PHE PHE D . n D 2 81 LYS 81 81 81 LYS LYS D . n D 2 82 MET 82 82 82 MET MET D . n D 2 83 ASN 83 83 83 ASN ASN D . n D 2 84 SER 84 84 84 SER SER D . n D 2 85 LEU 85 85 85 LEU LEU D . n D 2 86 GLN 86 86 86 GLN GLN D . n D 2 87 SER 87 87 87 SER SER D . n D 2 88 ASN 88 88 88 ASN ASN D . n D 2 89 ASP 89 89 89 ASP ASP D . n D 2 90 THR 90 90 90 THR THR D . n D 2 91 ALA 91 91 91 ALA ALA D . n D 2 92 ILE 92 92 92 ILE ILE D . n D 2 93 TYR 93 93 93 TYR TYR D . n D 2 94 TYR 94 94 94 TYR TYR D . n D 2 95 CYS 95 95 95 CYS CYS D . n D 2 96 ALA 96 96 96 ALA ALA D . n D 2 97 ARG 97 97 97 ARG ARG D . n D 2 98 ALA 98 98 98 ALA ALA D . n D 2 99 LEU 99 99 99 LEU LEU D . n D 2 100 THR 100 100 100 THR THR D . n D 2 101 TYR 101 101 101 TYR TYR D . n D 2 102 TYR 102 102 102 TYR TYR D . n D 2 103 ASP 103 103 103 ASP ASP D . n D 2 104 TYR 104 104 104 TYR TYR D . n D 2 105 GLU 105 105 105 GLU GLU D . n D 2 106 PHE 106 106 106 PHE PHE D . n D 2 107 ALA 107 107 107 ALA ALA D . n D 2 108 TYR 108 108 108 TYR TYR D . n D 2 109 TRP 109 109 109 TRP TRP D . n D 2 110 GLY 110 110 110 GLY GLY D . n D 2 111 GLN 111 111 111 GLN GLN D . n D 2 112 GLY 112 112 112 GLY GLY D . n D 2 113 THR 113 113 113 THR THR D . n D 2 114 LEU 114 114 114 LEU LEU D . n D 2 115 VAL 115 115 115 VAL VAL D . n D 2 116 THR 116 116 116 THR THR D . n D 2 117 VAL 117 117 117 VAL VAL D . n D 2 118 SER 118 118 118 SER SER D . n D 2 119 ALA 119 119 119 ALA ALA D . n D 2 120 ALA 120 120 120 ALA ALA D . n D 2 121 SER 121 121 121 SER SER D . n D 2 122 THR 122 122 122 THR THR D . n D 2 123 LYS 123 123 123 LYS LYS D . n D 2 124 GLY 124 124 124 GLY GLY D . n D 2 125 PRO 125 125 125 PRO PRO D . n D 2 126 SER 126 126 126 SER SER D . n D 2 127 VAL 127 127 127 VAL VAL D . n D 2 128 PHE 128 128 128 PHE PHE D . n D 2 129 PRO 129 129 129 PRO PRO D . n D 2 130 LEU 130 130 130 LEU LEU D . n D 2 131 ALA 131 131 131 ALA ALA D . n D 2 132 PRO 132 132 132 PRO PRO D . n D 2 133 SER 133 133 ? ? ? D . n D 2 134 SER 134 134 ? ? ? D . n D 2 135 LYS 135 135 ? ? ? D . n D 2 136 SER 136 136 ? ? ? D . n D 2 137 THR 137 137 ? ? ? D . n D 2 138 SER 138 138 ? ? ? D . n D 2 139 GLY 139 139 ? ? ? D . n D 2 140 GLY 140 140 140 GLY GLY D . n D 2 141 THR 141 141 141 THR THR D . n D 2 142 ALA 142 142 142 ALA ALA D . n D 2 143 ALA 143 143 143 ALA ALA D . n D 2 144 LEU 144 144 144 LEU LEU D . n D 2 145 GLY 145 145 145 GLY GLY D . n D 2 146 CYS 146 146 146 CYS CYS D . n D 2 147 LEU 147 147 147 LEU LEU D . n D 2 148 VAL 148 148 148 VAL VAL D . n D 2 149 LYS 149 149 149 LYS LYS D . n D 2 150 ASP 150 150 150 ASP ASP D . n D 2 151 TYR 151 151 151 TYR TYR D . n D 2 152 PHE 152 152 152 PHE PHE D . n D 2 153 PRO 153 153 153 PRO PRO D . n D 2 154 GLU 154 154 154 GLU GLU D . n D 2 155 PRO 155 155 155 PRO PRO D . n D 2 156 VAL 156 156 156 VAL VAL D . n D 2 157 THR 157 157 157 THR THR D . n D 2 158 VAL 158 158 158 VAL VAL D . n D 2 159 SER 159 159 159 SER SER D . n D 2 160 TRP 160 160 160 TRP TRP D . n D 2 161 ASN 161 161 161 ASN ASN D . n D 2 162 SER 162 162 162 SER SER D . n D 2 163 GLY 163 163 163 GLY GLY D . n D 2 164 ALA 164 164 164 ALA ALA D . n D 2 165 LEU 165 165 165 LEU LEU D . n D 2 166 THR 166 166 166 THR THR D . n D 2 167 SER 167 167 167 SER SER D . n D 2 168 GLY 168 168 168 GLY GLY D . n D 2 169 VAL 169 169 169 VAL VAL D . n D 2 170 HIS 170 170 170 HIS HIS D . n D 2 171 THR 171 171 171 THR THR D . n D 2 172 PHE 172 172 172 PHE PHE D . n D 2 173 PRO 173 173 173 PRO PRO D . n D 2 174 ALA 174 174 174 ALA ALA D . n D 2 175 VAL 175 175 175 VAL VAL D . n D 2 176 LEU 176 176 176 LEU LEU D . n D 2 177 GLN 177 177 177 GLN GLN D . n D 2 178 SER 178 178 178 SER SER D . n D 2 179 SER 179 179 179 SER SER D . n D 2 180 GLY 180 180 180 GLY GLY D . n D 2 181 LEU 181 181 181 LEU LEU D . n D 2 182 TYR 182 182 182 TYR TYR D . n D 2 183 SER 183 183 183 SER SER D . n D 2 184 LEU 184 184 184 LEU LEU D . n D 2 185 SER 185 185 185 SER SER D . n D 2 186 SER 186 186 186 SER SER D . n D 2 187 VAL 187 187 187 VAL VAL D . n D 2 188 VAL 188 188 188 VAL VAL D . n D 2 189 THR 189 189 189 THR THR D . n D 2 190 VAL 190 190 190 VAL VAL D . n D 2 191 PRO 191 191 191 PRO PRO D . n D 2 192 SER 192 192 192 SER SER D . n D 2 193 SER 193 193 193 SER SER D . n D 2 194 SER 194 194 194 SER SER D . n D 2 195 LEU 195 195 195 LEU LEU D . n D 2 196 GLY 196 196 196 GLY GLY D . n D 2 197 THR 197 197 197 THR THR D . n D 2 198 GLN 198 198 198 GLN GLN D . n D 2 199 THR 199 199 199 THR THR D . n D 2 200 TYR 200 200 200 TYR TYR D . n D 2 201 ILE 201 201 201 ILE ILE D . n D 2 202 CYS 202 202 202 CYS CYS D . n D 2 203 ASN 203 203 203 ASN ASN D . n D 2 204 VAL 204 204 204 VAL VAL D . n D 2 205 ASN 205 205 205 ASN ASN D . n D 2 206 HIS 206 206 206 HIS HIS D . n D 2 207 LYS 207 207 207 LYS LYS D . n D 2 208 PRO 208 208 208 PRO PRO D . n D 2 209 SER 209 209 209 SER SER D . n D 2 210 ASN 210 210 210 ASN ASN D . n D 2 211 THR 211 211 211 THR THR D . n D 2 212 LYS 212 212 212 LYS LYS D . n D 2 213 VAL 213 213 213 VAL VAL D . n D 2 214 ASP 214 214 214 ASP ASP D . n D 2 215 LYS 215 215 215 LYS LYS D . n D 2 216 ARG 216 216 216 ARG ARG D . n D 2 217 VAL 217 217 217 VAL VAL D . n D 2 218 GLU 218 218 218 GLU GLU D . n D 2 219 PRO 219 219 219 PRO PRO D . n D 2 220 LYS 220 220 220 LYS LYS D . n E 3 1 CYS 1 1 1 CYS CYS E . n E 3 2 GLN 2 2 2 GLN GLN E . n E 3 3 HIS 3 3 3 HIS HIS E . n E 3 4 ASP 4 4 4 ASP ASP E . n E 3 5 LEU 5 5 5 LEU LEU E . n E 3 6 SER 6 6 6 SER SER E . n E 3 7 THR 7 7 7 THR THR E . n E 3 8 ARG 8 8 8 ARG ARG E . n E 3 9 ARG 9 9 9 ARG ARG E . n E 3 10 LEU 10 10 10 LEU LEU E . n E 3 11 LYS 11 11 11 LYS LYS E . n E 3 12 CYS 12 12 12 CYS CYS E . n F 3 1 CYS 1 1 1 CYS CYS F . n F 3 2 GLN 2 2 2 GLN GLN F . n F 3 3 HIS 3 3 3 HIS HIS F . n F 3 4 ASP 4 4 4 ASP ASP F . n F 3 5 LEU 5 5 5 LEU LEU F . n F 3 6 SER 6 6 6 SER SER F . n F 3 7 THR 7 7 7 THR THR F . n F 3 8 ARG 8 8 8 ARG ARG F . n F 3 9 ARG 9 9 9 ARG ARG F . n F 3 10 LEU 10 10 10 LEU LEU F . n F 3 11 LYS 11 11 11 LYS LYS F . n F 3 12 CYS 12 12 12 CYS CYS F . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code G 4 PO4 1 301 2 PO4 PO4 A . H 4 PO4 1 302 3 PO4 PO4 A . I 5 NAG 1 301 222 NAG NAG B . J 4 PO4 1 302 4 PO4 PO4 B . K 6 MRY 1 301 1 MRY MRY C . L 5 NAG 1 301 222 NAG NAG D . M 4 PO4 1 302 1 PO4 PO4 D . N 7 HOH 1 401 21 HOH HOH A . N 7 HOH 2 402 78 HOH HOH A . N 7 HOH 3 403 261 HOH HOH A . N 7 HOH 4 404 139 HOH HOH A . N 7 HOH 5 405 306 HOH HOH A . N 7 HOH 6 406 218 HOH HOH A . N 7 HOH 7 407 210 HOH HOH A . N 7 HOH 8 408 376 HOH HOH A . N 7 HOH 9 409 287 HOH HOH A . N 7 HOH 10 410 9 HOH HOH A . N 7 HOH 11 411 5 HOH HOH A . N 7 HOH 12 412 368 HOH HOH A . N 7 HOH 13 413 19 HOH HOH A . N 7 HOH 14 414 127 HOH HOH A . N 7 HOH 15 415 69 HOH HOH A . N 7 HOH 16 416 25 HOH HOH A . N 7 HOH 17 417 365 HOH HOH A . N 7 HOH 18 418 85 HOH HOH A . N 7 HOH 19 419 234 HOH HOH A . N 7 HOH 20 420 90 HOH HOH A . N 7 HOH 21 421 6 HOH HOH A . N 7 HOH 22 422 52 HOH HOH A . N 7 HOH 23 423 149 HOH HOH A . N 7 HOH 24 424 164 HOH HOH A . N 7 HOH 25 425 54 HOH HOH A . N 7 HOH 26 426 162 HOH HOH A . N 7 HOH 27 427 163 HOH HOH A . N 7 HOH 28 428 47 HOH HOH A . N 7 HOH 29 429 259 HOH HOH A . N 7 HOH 30 430 137 HOH HOH A . N 7 HOH 31 431 96 HOH HOH A . N 7 HOH 32 432 180 HOH HOH A . N 7 HOH 33 433 339 HOH HOH A . N 7 HOH 34 434 97 HOH HOH A . N 7 HOH 35 435 110 HOH HOH A . N 7 HOH 36 436 268 HOH HOH A . N 7 HOH 37 437 3 HOH HOH A . N 7 HOH 38 438 32 HOH HOH A . N 7 HOH 39 439 281 HOH HOH A . N 7 HOH 40 440 184 HOH HOH A . N 7 HOH 41 441 135 HOH HOH A . N 7 HOH 42 442 284 HOH HOH A . N 7 HOH 43 443 99 HOH HOH A . N 7 HOH 44 444 344 HOH HOH A . N 7 HOH 45 445 77 HOH HOH A . N 7 HOH 46 446 76 HOH HOH A . N 7 HOH 47 447 105 HOH HOH A . N 7 HOH 48 448 192 HOH HOH A . N 7 HOH 49 449 272 HOH HOH A . N 7 HOH 50 450 225 HOH HOH A . N 7 HOH 51 451 117 HOH HOH A . N 7 HOH 52 452 326 HOH HOH A . N 7 HOH 53 453 408 HOH HOH A . N 7 HOH 54 454 107 HOH HOH A . N 7 HOH 55 455 141 HOH HOH A . N 7 HOH 56 456 345 HOH HOH A . N 7 HOH 57 457 233 HOH HOH A . N 7 HOH 58 458 121 HOH HOH A . N 7 HOH 59 459 148 HOH HOH A . N 7 HOH 60 460 62 HOH HOH A . N 7 HOH 61 461 153 HOH HOH A . N 7 HOH 62 462 264 HOH HOH A . N 7 HOH 63 463 72 HOH HOH A . N 7 HOH 64 464 84 HOH HOH A . N 7 HOH 65 465 64 HOH HOH A . N 7 HOH 66 466 103 HOH HOH A . N 7 HOH 67 467 354 HOH HOH A . N 7 HOH 68 468 189 HOH HOH A . N 7 HOH 69 469 86 HOH HOH A . N 7 HOH 70 470 413 HOH HOH A . N 7 HOH 71 471 106 HOH HOH A . N 7 HOH 72 472 197 HOH HOH A . N 7 HOH 73 473 310 HOH HOH A . N 7 HOH 74 474 34 HOH HOH A . N 7 HOH 75 475 182 HOH HOH A . N 7 HOH 76 476 304 HOH HOH A . N 7 HOH 77 477 215 HOH HOH A . N 7 HOH 78 478 278 HOH HOH A . N 7 HOH 79 479 307 HOH HOH A . N 7 HOH 80 480 36 HOH HOH A . N 7 HOH 81 481 410 HOH HOH A . N 7 HOH 82 482 380 HOH HOH A . N 7 HOH 83 483 373 HOH HOH A . N 7 HOH 84 484 384 HOH HOH A . N 7 HOH 85 485 191 HOH HOH A . N 7 HOH 86 486 415 HOH HOH A . N 7 HOH 87 487 333 HOH HOH A . N 7 HOH 88 488 33 HOH HOH A . N 7 HOH 89 489 170 HOH HOH A . N 7 HOH 90 490 231 HOH HOH A . N 7 HOH 91 491 263 HOH HOH A . N 7 HOH 92 492 209 HOH HOH A . N 7 HOH 93 493 143 HOH HOH A . N 7 HOH 94 494 112 HOH HOH A . N 7 HOH 95 495 409 HOH HOH A . N 7 HOH 96 496 212 HOH HOH A . N 7 HOH 97 497 196 HOH HOH A . N 7 HOH 98 498 389 HOH HOH A . N 7 HOH 99 499 246 HOH HOH A . N 7 HOH 100 500 247 HOH HOH A . N 7 HOH 101 501 419 HOH HOH A . N 7 HOH 102 502 214 HOH HOH A . N 7 HOH 103 503 115 HOH HOH A . N 7 HOH 104 504 227 HOH HOH A . N 7 HOH 105 505 398 HOH HOH A . N 7 HOH 106 506 270 HOH HOH A . N 7 HOH 107 507 244 HOH HOH A . N 7 HOH 108 508 386 HOH HOH A . N 7 HOH 109 509 222 HOH HOH A . N 7 HOH 110 510 181 HOH HOH A . O 7 HOH 1 401 378 HOH HOH B . O 7 HOH 2 402 254 HOH HOH B . O 7 HOH 3 403 266 HOH HOH B . O 7 HOH 4 404 332 HOH HOH B . O 7 HOH 5 405 41 HOH HOH B . O 7 HOH 6 406 20 HOH HOH B . O 7 HOH 7 407 4 HOH HOH B . O 7 HOH 8 408 113 HOH HOH B . O 7 HOH 9 409 51 HOH HOH B . O 7 HOH 10 410 318 HOH HOH B . O 7 HOH 11 411 17 HOH HOH B . O 7 HOH 12 412 190 HOH HOH B . O 7 HOH 13 413 11 HOH HOH B . O 7 HOH 14 414 167 HOH HOH B . O 7 HOH 15 415 299 HOH HOH B . O 7 HOH 16 416 23 HOH HOH B . O 7 HOH 17 417 102 HOH HOH B . O 7 HOH 18 418 336 HOH HOH B . O 7 HOH 19 419 79 HOH HOH B . O 7 HOH 20 420 194 HOH HOH B . O 7 HOH 21 421 403 HOH HOH B . O 7 HOH 22 422 358 HOH HOH B . O 7 HOH 23 423 73 HOH HOH B . O 7 HOH 24 424 147 HOH HOH B . O 7 HOH 25 425 173 HOH HOH B . O 7 HOH 26 426 50 HOH HOH B . O 7 HOH 27 427 371 HOH HOH B . O 7 HOH 28 428 42 HOH HOH B . O 7 HOH 29 429 100 HOH HOH B . O 7 HOH 30 430 22 HOH HOH B . O 7 HOH 31 431 46 HOH HOH B . O 7 HOH 32 432 301 HOH HOH B . O 7 HOH 33 433 188 HOH HOH B . O 7 HOH 34 434 91 HOH HOH B . O 7 HOH 35 435 59 HOH HOH B . O 7 HOH 36 436 172 HOH HOH B . O 7 HOH 37 437 362 HOH HOH B . O 7 HOH 38 438 171 HOH HOH B . O 7 HOH 39 439 418 HOH HOH B . O 7 HOH 40 440 154 HOH HOH B . O 7 HOH 41 441 145 HOH HOH B . O 7 HOH 42 442 237 HOH HOH B . O 7 HOH 43 443 294 HOH HOH B . O 7 HOH 44 444 48 HOH HOH B . O 7 HOH 45 445 116 HOH HOH B . O 7 HOH 46 446 128 HOH HOH B . O 7 HOH 47 447 343 HOH HOH B . O 7 HOH 48 448 323 HOH HOH B . O 7 HOH 49 449 235 HOH HOH B . O 7 HOH 50 450 92 HOH HOH B . O 7 HOH 51 451 277 HOH HOH B . O 7 HOH 52 452 405 HOH HOH B . O 7 HOH 53 453 201 HOH HOH B . O 7 HOH 54 454 223 HOH HOH B . O 7 HOH 55 455 239 HOH HOH B . O 7 HOH 56 456 360 HOH HOH B . O 7 HOH 57 457 308 HOH HOH B . O 7 HOH 58 458 83 HOH HOH B . O 7 HOH 59 459 126 HOH HOH B . O 7 HOH 60 460 302 HOH HOH B . O 7 HOH 61 461 35 HOH HOH B . O 7 HOH 62 462 420 HOH HOH B . O 7 HOH 63 463 288 HOH HOH B . O 7 HOH 64 464 289 HOH HOH B . O 7 HOH 65 465 311 HOH HOH B . O 7 HOH 66 466 251 HOH HOH B . O 7 HOH 67 467 396 HOH HOH B . O 7 HOH 68 468 168 HOH HOH B . O 7 HOH 69 469 144 HOH HOH B . O 7 HOH 70 470 193 HOH HOH B . O 7 HOH 71 471 293 HOH HOH B . O 7 HOH 72 472 406 HOH HOH B . O 7 HOH 73 473 74 HOH HOH B . O 7 HOH 74 474 347 HOH HOH B . O 7 HOH 75 475 382 HOH HOH B . O 7 HOH 76 476 397 HOH HOH B . O 7 HOH 77 477 275 HOH HOH B . O 7 HOH 78 478 370 HOH HOH B . O 7 HOH 79 479 327 HOH HOH B . O 7 HOH 80 480 377 HOH HOH B . O 7 HOH 81 481 402 HOH HOH B . O 7 HOH 82 482 334 HOH HOH B . O 7 HOH 83 483 383 HOH HOH B . O 7 HOH 84 484 120 HOH HOH B . O 7 HOH 85 485 217 HOH HOH B . O 7 HOH 86 486 387 HOH HOH B . O 7 HOH 87 487 305 HOH HOH B . O 7 HOH 88 488 296 HOH HOH B . O 7 HOH 89 489 260 HOH HOH B . O 7 HOH 90 490 226 HOH HOH B . O 7 HOH 91 491 241 HOH HOH B . O 7 HOH 92 492 330 HOH HOH B . O 7 HOH 93 493 417 HOH HOH B . O 7 HOH 94 494 37 HOH HOH B . O 7 HOH 95 495 274 HOH HOH B . O 7 HOH 96 496 156 HOH HOH B . O 7 HOH 97 497 242 HOH HOH B . P 7 HOH 1 401 291 HOH HOH C . P 7 HOH 2 402 369 HOH HOH C . P 7 HOH 3 403 279 HOH HOH C . P 7 HOH 4 404 202 HOH HOH C . P 7 HOH 5 405 88 HOH HOH C . P 7 HOH 6 406 8 HOH HOH C . P 7 HOH 7 407 395 HOH HOH C . P 7 HOH 8 408 175 HOH HOH C . P 7 HOH 9 409 82 HOH HOH C . P 7 HOH 10 410 375 HOH HOH C . P 7 HOH 11 411 63 HOH HOH C . P 7 HOH 12 412 66 HOH HOH C . P 7 HOH 13 413 240 HOH HOH C . P 7 HOH 14 414 200 HOH HOH C . P 7 HOH 15 415 178 HOH HOH C . P 7 HOH 16 416 95 HOH HOH C . P 7 HOH 17 417 158 HOH HOH C . P 7 HOH 18 418 138 HOH HOH C . P 7 HOH 19 419 338 HOH HOH C . P 7 HOH 20 420 152 HOH HOH C . P 7 HOH 21 421 14 HOH HOH C . P 7 HOH 22 422 374 HOH HOH C . P 7 HOH 23 423 70 HOH HOH C . P 7 HOH 24 424 18 HOH HOH C . P 7 HOH 25 425 43 HOH HOH C . P 7 HOH 26 426 186 HOH HOH C . P 7 HOH 27 427 385 HOH HOH C . P 7 HOH 28 428 2 HOH HOH C . P 7 HOH 29 429 257 HOH HOH C . P 7 HOH 30 430 10 HOH HOH C . P 7 HOH 31 431 350 HOH HOH C . P 7 HOH 32 432 265 HOH HOH C . P 7 HOH 33 433 422 HOH HOH C . P 7 HOH 34 434 125 HOH HOH C . P 7 HOH 35 435 391 HOH HOH C . P 7 HOH 36 436 45 HOH HOH C . P 7 HOH 37 437 15 HOH HOH C . P 7 HOH 38 438 57 HOH HOH C . P 7 HOH 39 439 195 HOH HOH C . P 7 HOH 40 440 16 HOH HOH C . P 7 HOH 41 441 133 HOH HOH C . P 7 HOH 42 442 276 HOH HOH C . P 7 HOH 43 443 303 HOH HOH C . P 7 HOH 44 444 101 HOH HOH C . P 7 HOH 45 445 319 HOH HOH C . P 7 HOH 46 446 205 HOH HOH C . P 7 HOH 47 447 157 HOH HOH C . P 7 HOH 48 448 340 HOH HOH C . P 7 HOH 49 449 28 HOH HOH C . P 7 HOH 50 450 131 HOH HOH C . P 7 HOH 51 451 174 HOH HOH C . P 7 HOH 52 452 367 HOH HOH C . P 7 HOH 53 453 199 HOH HOH C . P 7 HOH 54 454 228 HOH HOH C . P 7 HOH 55 455 221 HOH HOH C . P 7 HOH 56 456 55 HOH HOH C . P 7 HOH 57 457 185 HOH HOH C . P 7 HOH 58 458 142 HOH HOH C . P 7 HOH 59 459 357 HOH HOH C . P 7 HOH 60 460 342 HOH HOH C . P 7 HOH 61 461 295 HOH HOH C . P 7 HOH 62 462 89 HOH HOH C . P 7 HOH 63 463 238 HOH HOH C . P 7 HOH 64 464 53 HOH HOH C . P 7 HOH 65 465 316 HOH HOH C . P 7 HOH 66 466 325 HOH HOH C . P 7 HOH 67 467 273 HOH HOH C . P 7 HOH 68 468 329 HOH HOH C . P 7 HOH 69 469 165 HOH HOH C . P 7 HOH 70 470 151 HOH HOH C . P 7 HOH 71 471 123 HOH HOH C . P 7 HOH 72 472 224 HOH HOH C . P 7 HOH 73 473 136 HOH HOH C . P 7 HOH 74 474 49 HOH HOH C . P 7 HOH 75 475 134 HOH HOH C . P 7 HOH 76 476 262 HOH HOH C . P 7 HOH 77 477 219 HOH HOH C . P 7 HOH 78 478 280 HOH HOH C . P 7 HOH 79 479 80 HOH HOH C . P 7 HOH 80 480 12 HOH HOH C . P 7 HOH 81 481 30 HOH HOH C . P 7 HOH 82 482 150 HOH HOH C . P 7 HOH 83 483 160 HOH HOH C . P 7 HOH 84 484 130 HOH HOH C . P 7 HOH 85 485 364 HOH HOH C . P 7 HOH 86 486 198 HOH HOH C . P 7 HOH 87 487 356 HOH HOH C . P 7 HOH 88 488 98 HOH HOH C . P 7 HOH 89 489 372 HOH HOH C . P 7 HOH 90 490 230 HOH HOH C . P 7 HOH 91 491 114 HOH HOH C . P 7 HOH 92 492 423 HOH HOH C . P 7 HOH 93 493 111 HOH HOH C . P 7 HOH 94 494 283 HOH HOH C . P 7 HOH 95 495 312 HOH HOH C . P 7 HOH 96 496 351 HOH HOH C . P 7 HOH 97 497 269 HOH HOH C . P 7 HOH 98 498 314 HOH HOH C . P 7 HOH 99 499 379 HOH HOH C . P 7 HOH 100 500 346 HOH HOH C . P 7 HOH 101 501 337 HOH HOH C . P 7 HOH 102 502 282 HOH HOH C . P 7 HOH 103 503 392 HOH HOH C . P 7 HOH 104 504 421 HOH HOH C . P 7 HOH 105 505 216 HOH HOH C . P 7 HOH 106 506 400 HOH HOH C . P 7 HOH 107 507 176 HOH HOH C . P 7 HOH 108 508 220 HOH HOH C . P 7 HOH 109 509 324 HOH HOH C . P 7 HOH 110 510 248 HOH HOH C . P 7 HOH 111 511 255 HOH HOH C . P 7 HOH 112 512 243 HOH HOH C . Q 7 HOH 1 401 207 HOH HOH D . Q 7 HOH 2 402 7 HOH HOH D . Q 7 HOH 3 403 211 HOH HOH D . Q 7 HOH 4 404 140 HOH HOH D . Q 7 HOH 5 405 236 HOH HOH D . Q 7 HOH 6 406 44 HOH HOH D . Q 7 HOH 7 407 271 HOH HOH D . Q 7 HOH 8 408 119 HOH HOH D . Q 7 HOH 9 409 399 HOH HOH D . Q 7 HOH 10 410 341 HOH HOH D . Q 7 HOH 11 411 1 HOH HOH D . Q 7 HOH 12 412 31 HOH HOH D . Q 7 HOH 13 413 13 HOH HOH D . Q 7 HOH 14 414 65 HOH HOH D . Q 7 HOH 15 415 81 HOH HOH D . Q 7 HOH 16 416 118 HOH HOH D . Q 7 HOH 17 417 313 HOH HOH D . Q 7 HOH 18 418 393 HOH HOH D . Q 7 HOH 19 419 27 HOH HOH D . Q 7 HOH 20 420 204 HOH HOH D . Q 7 HOH 21 421 124 HOH HOH D . Q 7 HOH 22 422 407 HOH HOH D . Q 7 HOH 23 423 166 HOH HOH D . Q 7 HOH 24 424 67 HOH HOH D . Q 7 HOH 25 425 177 HOH HOH D . Q 7 HOH 26 426 252 HOH HOH D . Q 7 HOH 27 427 87 HOH HOH D . Q 7 HOH 28 428 366 HOH HOH D . Q 7 HOH 29 429 245 HOH HOH D . Q 7 HOH 30 430 132 HOH HOH D . Q 7 HOH 31 431 61 HOH HOH D . Q 7 HOH 32 432 104 HOH HOH D . Q 7 HOH 33 433 179 HOH HOH D . Q 7 HOH 34 434 38 HOH HOH D . Q 7 HOH 35 435 75 HOH HOH D . Q 7 HOH 36 436 40 HOH HOH D . Q 7 HOH 37 437 39 HOH HOH D . Q 7 HOH 38 438 56 HOH HOH D . Q 7 HOH 39 439 309 HOH HOH D . Q 7 HOH 40 440 58 HOH HOH D . Q 7 HOH 41 441 414 HOH HOH D . Q 7 HOH 42 442 68 HOH HOH D . Q 7 HOH 43 443 169 HOH HOH D . Q 7 HOH 44 444 348 HOH HOH D . Q 7 HOH 45 445 298 HOH HOH D . Q 7 HOH 46 446 412 HOH HOH D . Q 7 HOH 47 447 381 HOH HOH D . Q 7 HOH 48 448 187 HOH HOH D . Q 7 HOH 49 449 122 HOH HOH D . Q 7 HOH 50 450 94 HOH HOH D . Q 7 HOH 51 451 206 HOH HOH D . Q 7 HOH 52 452 93 HOH HOH D . Q 7 HOH 53 453 109 HOH HOH D . Q 7 HOH 54 454 213 HOH HOH D . Q 7 HOH 55 455 24 HOH HOH D . Q 7 HOH 56 456 129 HOH HOH D . Q 7 HOH 57 457 249 HOH HOH D . Q 7 HOH 58 458 416 HOH HOH D . Q 7 HOH 59 459 361 HOH HOH D . Q 7 HOH 60 460 155 HOH HOH D . Q 7 HOH 61 461 26 HOH HOH D . Q 7 HOH 62 462 335 HOH HOH D . Q 7 HOH 63 463 161 HOH HOH D . Q 7 HOH 64 464 208 HOH HOH D . Q 7 HOH 65 465 349 HOH HOH D . Q 7 HOH 66 466 328 HOH HOH D . Q 7 HOH 67 467 363 HOH HOH D . Q 7 HOH 68 468 352 HOH HOH D . Q 7 HOH 69 469 250 HOH HOH D . Q 7 HOH 70 470 404 HOH HOH D . Q 7 HOH 71 471 29 HOH HOH D . Q 7 HOH 72 472 394 HOH HOH D . Q 7 HOH 73 473 159 HOH HOH D . Q 7 HOH 74 474 146 HOH HOH D . Q 7 HOH 75 475 285 HOH HOH D . Q 7 HOH 76 476 322 HOH HOH D . Q 7 HOH 77 477 229 HOH HOH D . Q 7 HOH 78 478 331 HOH HOH D . Q 7 HOH 79 479 256 HOH HOH D . Q 7 HOH 80 480 411 HOH HOH D . Q 7 HOH 81 481 297 HOH HOH D . Q 7 HOH 82 482 253 HOH HOH D . R 7 HOH 1 101 71 HOH HOH E . R 7 HOH 2 102 203 HOH HOH E . R 7 HOH 3 103 183 HOH HOH E . R 7 HOH 4 104 60 HOH HOH E . R 7 HOH 5 105 300 HOH HOH E . R 7 HOH 6 106 232 HOH HOH E . S 7 HOH 1 101 320 HOH HOH F . S 7 HOH 2 102 108 HOH HOH F . S 7 HOH 3 103 321 HOH HOH F . # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA trimeric 3 2 author_and_software_defined_assembly PISA trimeric 3 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,B,E,G,H,I,J,N,O,R 2 1 C,D,F,K,L,M,P,Q,S # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 6190 ? 1 MORE -43 ? 1 'SSA (A^2)' 18550 ? 2 'ABSA (A^2)' 5760 ? 2 MORE -28 ? 2 'SSA (A^2)' 18570 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2016-10-26 2 'Structure model' 1 1 2016-11-09 3 'Structure model' 1 2 2017-12-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Database references' 3 3 'Structure model' 'Derived calculations' # loop_ _pdbx_audit_revision_category.ordinal _pdbx_audit_revision_category.revision_ordinal _pdbx_audit_revision_category.data_content_type _pdbx_audit_revision_category.category 1 3 'Structure model' citation 2 3 'Structure model' pdbx_struct_oper_list # loop_ _pdbx_audit_revision_item.ordinal _pdbx_audit_revision_item.revision_ordinal _pdbx_audit_revision_item.data_content_type _pdbx_audit_revision_item.item 1 3 'Structure model' '_citation.journal_abbrev' 2 3 'Structure model' '_citation.page_first' 3 3 'Structure model' '_citation.page_last' 4 3 'Structure model' '_citation.pdbx_database_id_DOI' 5 3 'Structure model' '_citation.pdbx_database_id_PubMed' 6 3 'Structure model' '_citation.title' 7 3 'Structure model' '_pdbx_struct_oper_list.symmetry_operation' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? dev_1426 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? XSCALE ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? . 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 O A HOH 476 ? ? O A HOH 484 ? ? 1.90 2 1 O A HOH 450 ? ? O A HOH 508 ? ? 1.93 3 1 N F CYS 1 ? ? O F HOH 101 ? ? 1.93 4 1 O D TRP 109 ? ? O D HOH 401 ? ? 1.98 5 1 OE2 C GLU 123 ? A O C HOH 401 ? ? 2.01 6 1 O D HOH 426 ? ? O D HOH 470 ? ? 2.01 7 1 OG1 C THR 178 ? ? O C HOH 402 ? ? 2.01 8 1 OD2 C ASP 170 ? ? O C HOH 403 ? ? 2.02 9 1 OD2 C ASP 185 ? ? O C HOH 404 ? ? 2.05 10 1 NZ C LYS 183 ? ? O C HOH 405 ? ? 2.05 11 1 O A HOH 426 ? ? O C HOH 453 ? ? 2.06 12 1 O A GLN 166 ? ? O A HOH 401 ? ? 2.07 13 1 O C HOH 481 ? ? O D HOH 454 ? ? 2.08 14 1 O C HOH 435 ? ? O C HOH 465 ? ? 2.08 15 1 O C HOH 445 ? ? O C HOH 455 ? ? 2.09 16 1 O A HOH 474 ? ? O A HOH 479 ? ? 2.09 17 1 O D HOH 405 ? ? O D HOH 430 ? ? 2.12 18 1 O B HOH 446 ? ? O B HOH 487 ? ? 2.12 19 1 O A THR 178 ? ? O A HOH 402 ? ? 2.13 20 1 O D HOH 405 ? ? O D HOH 481 ? ? 2.14 21 1 OG1 C THR 180 ? ? O C HOH 406 ? ? 2.14 22 1 OG1 C THR 129 ? ? O C HOH 407 ? ? 2.16 23 1 O A ILE 55 ? ? O A HOH 403 ? ? 2.17 24 1 O A HOH 455 ? ? O A HOH 490 ? ? 2.19 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 GLN A 27 ? ? -173.70 142.99 2 1 ALA A 51 ? ? 70.28 -45.67 3 1 ALA A 84 ? ? 177.51 175.06 4 1 ASN A 91 ? ? -142.54 29.26 5 1 ASN A 152 ? ? 57.74 3.27 6 1 SER B 84 ? ? 39.00 76.21 7 1 ALA B 120 ? ? -68.40 -169.80 8 1 SER B 133 ? ? -156.50 -156.15 9 1 ASN C 41 ? ? 63.06 -3.87 10 1 ALA C 51 ? ? 73.98 -51.74 11 1 SER D 15 ? ? 75.28 -15.33 12 1 ARG D 66 ? ? -143.69 11.80 13 1 ALA D 120 ? ? -57.84 172.59 14 1 ASN D 210 ? ? 49.77 25.78 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A LYS 169 ? CG ? A LYS 169 CG 2 1 Y 1 A LYS 169 ? CD ? A LYS 169 CD 3 1 Y 1 A LYS 169 ? CE ? A LYS 169 CE 4 1 Y 1 A LYS 169 ? NZ ? A LYS 169 NZ 5 1 Y 1 B GLN 1 ? CG ? B GLN 1 CG 6 1 Y 1 B GLN 1 ? CD ? B GLN 1 CD 7 1 Y 1 B GLN 1 ? OE1 ? B GLN 1 OE1 8 1 Y 1 B GLN 1 ? NE2 ? B GLN 1 NE2 9 1 Y 1 C LYS 169 ? CG ? C LYS 169 CG 10 1 Y 1 C LYS 169 ? CD ? C LYS 169 CD 11 1 Y 1 C LYS 169 ? CE ? C LYS 169 CE 12 1 Y 1 C LYS 169 ? NZ ? C LYS 169 NZ 13 1 Y 1 D GLN 1 ? CG ? D GLN 1 CG 14 1 Y 1 D GLN 1 ? CD ? D GLN 1 CD 15 1 Y 1 D GLN 1 ? OE1 ? D GLN 1 OE1 16 1 Y 1 D GLN 1 ? NE2 ? D GLN 1 NE2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ALA 213 ? A ALA 213 2 1 Y 1 D SER 133 ? D SER 133 3 1 Y 1 D SER 134 ? D SER 134 4 1 Y 1 D LYS 135 ? D LYS 135 5 1 Y 1 D SER 136 ? D SER 136 6 1 Y 1 D THR 137 ? D THR 137 7 1 Y 1 D SER 138 ? D SER 138 8 1 Y 1 D GLY 139 ? D GLY 139 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 4 'PHOSPHATE ION' PO4 5 N-ACETYL-D-GLUCOSAMINE NAG 6 MESO-ERYTHRITOL MRY 7 water HOH #