data_5EBE # _entry.id 5EBE # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5EBE WWPDB D_1000214646 # _pdbx_database_related.db_name PDB _pdbx_database_related.details . _pdbx_database_related.db_id 5EBB _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5EBE _pdbx_database_status.recvd_initial_deposition_date 2015-10-19 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBE _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Lim, S.M.' 1 'Yeung, K.' 2 'Tresaugues, L.' 3 'Teo, H.L.' 4 'Nordlund, P.' 5 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country UK _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'Febs J.' _citation.journal_id_ASTM ? _citation.journal_id_CSD ? _citation.journal_id_ISSN 1742-464X _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 283 _citation.language ? _citation.page_first 1107 _citation.page_last 1123 _citation.title ;The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a - an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity. ; _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1111/febs.13655 _citation.pdbx_database_id_PubMed 26783088 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Lim, S.M.' 1 primary 'Yeung, K.' 2 primary 'Tresaugues, L.' 3 primary 'Ling, T.H.' 4 primary 'Nordlund, P.' 5 # _cell.angle_alpha 90.00 _cell.angle_alpha_esd ? _cell.angle_beta 90.00 _cell.angle_beta_esd ? _cell.angle_gamma 120.00 _cell.angle_gamma_esd ? _cell.entry_id 5EBE _cell.details ? _cell.formula_units_Z ? _cell.length_a 147.654 _cell.length_a_esd ? _cell.length_b 147.654 _cell.length_b_esd ? _cell.length_c 142.298 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 12 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 5EBE _symmetry.cell_setting ? _symmetry.Int_Tables_number 154 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'P 32 2 1' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Acid sphingomyelinase-like phosphodiesterase 3a' 47597.648 1 3.1.4.- ? ? ? 2 polymer man 'Acid sphingomyelinase-like phosphodiesterase 3a' 47192.141 2 3.1.4.- ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 13 ? ? ? ? 4 non-polymer syn 'ZINC ION' 65.409 6 ? ? ? ? 5 non-polymer syn "CYTIDINE-5'-MONOPHOSPHATE" 323.197 2 ? ? ? ? 6 non-polymer syn GLYCEROL 92.094 2 ? ? ? ? 7 non-polymer syn 'MALONATE ION' 102.046 1 ? ? ? ? 8 non-polymer syn 5-O-phosphono-beta-D-ribofuranose 230.110 1 ? ? ? ? 9 non-polymer syn 'THIOCYANATE ION' 58.082 2 ? ? ? ? 10 water nat water 18.015 130 ? ? ? ? # loop_ _entity_name_com.entity_id _entity_name_com.name 1 'ASM-like phosphodiesterase 3a' 2 'ASM-like phosphodiesterase 3a' # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;PPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSP PHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGF YSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYN EKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQ YYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAI MNLDNISYADCLKQLYIK ; ;PPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSP PHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGF YSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYN EKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQ YYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAI MNLDNISYADCLKQLYIK ; A ? 2 'polypeptide(L)' no no ;PPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSP PHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGF YSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYN EKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQ YYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAI MNLDNISYADCLKQL ; ;PPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSP PHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGF YSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYN EKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQ YYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAI MNLDNISYADCLKQL ; B,C ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 PRO n 1 2 PRO n 1 3 PRO n 1 4 ALA n 1 5 ILE n 1 6 GLY n 1 7 GLN n 1 8 PHE n 1 9 TRP n 1 10 HIS n 1 11 VAL n 1 12 THR n 1 13 ASP n 1 14 LEU n 1 15 HIS n 1 16 LEU n 1 17 ASP n 1 18 PRO n 1 19 THR n 1 20 TYR n 1 21 HIS n 1 22 ILE n 1 23 THR n 1 24 ASP n 1 25 ASP n 1 26 HIS n 1 27 THR n 1 28 LYS n 1 29 VAL n 1 30 CYS n 1 31 ALA n 1 32 SER n 1 33 SER n 1 34 LYS n 1 35 GLY n 1 36 ALA n 1 37 ASN n 1 38 ALA n 1 39 SER n 1 40 ASN n 1 41 PRO n 1 42 GLY n 1 43 PRO n 1 44 PHE n 1 45 GLY n 1 46 ASP n 1 47 VAL n 1 48 LEU n 1 49 CYS n 1 50 ASP n 1 51 SER n 1 52 PRO n 1 53 TYR n 1 54 GLN n 1 55 LEU n 1 56 ILE n 1 57 LEU n 1 58 SER n 1 59 ALA n 1 60 PHE n 1 61 ASP n 1 62 PHE n 1 63 ILE n 1 64 LYS n 1 65 ASN n 1 66 SER n 1 67 GLY n 1 68 GLN n 1 69 GLU n 1 70 ALA n 1 71 SER n 1 72 PHE n 1 73 MET n 1 74 ILE n 1 75 TRP n 1 76 THR n 1 77 GLY n 1 78 ASP n 1 79 SER n 1 80 PRO n 1 81 PRO n 1 82 HIS n 1 83 VAL n 1 84 PRO n 1 85 VAL n 1 86 PRO n 1 87 GLU n 1 88 LEU n 1 89 SER n 1 90 THR n 1 91 ASP n 1 92 THR n 1 93 VAL n 1 94 ILE n 1 95 ASN n 1 96 VAL n 1 97 ILE n 1 98 THR n 1 99 ASN n 1 100 MET n 1 101 THR n 1 102 THR n 1 103 THR n 1 104 ILE n 1 105 GLN n 1 106 SER n 1 107 LEU n 1 108 PHE n 1 109 PRO n 1 110 ASN n 1 111 LEU n 1 112 GLN n 1 113 VAL n 1 114 PHE n 1 115 PRO n 1 116 ALA n 1 117 LEU n 1 118 GLY n 1 119 ASN n 1 120 HIS n 1 121 ASP n 1 122 TYR n 1 123 TRP n 1 124 PRO n 1 125 GLN n 1 126 ASP n 1 127 GLN n 1 128 LEU n 1 129 PRO n 1 130 VAL n 1 131 VAL n 1 132 THR n 1 133 SER n 1 134 LYS n 1 135 VAL n 1 136 TYR n 1 137 ASN n 1 138 ALA n 1 139 VAL n 1 140 ALA n 1 141 ASN n 1 142 LEU n 1 143 TRP n 1 144 LYS n 1 145 PRO n 1 146 TRP n 1 147 LEU n 1 148 ASP n 1 149 GLU n 1 150 GLU n 1 151 ALA n 1 152 ILE n 1 153 SER n 1 154 THR n 1 155 LEU n 1 156 ARG n 1 157 LYS n 1 158 GLY n 1 159 GLY n 1 160 PHE n 1 161 TYR n 1 162 SER n 1 163 GLN n 1 164 LYS n 1 165 VAL n 1 166 THR n 1 167 THR n 1 168 ASN n 1 169 PRO n 1 170 ASN n 1 171 LEU n 1 172 ARG n 1 173 ILE n 1 174 ILE n 1 175 SER n 1 176 LEU n 1 177 ASN n 1 178 THR n 1 179 ASN n 1 180 LEU n 1 181 TYR n 1 182 TYR n 1 183 GLY n 1 184 PRO n 1 185 ASN n 1 186 ILE n 1 187 MET n 1 188 THR n 1 189 LEU n 1 190 ASN n 1 191 LYS n 1 192 THR n 1 193 ASP n 1 194 PRO n 1 195 ALA n 1 196 ASN n 1 197 GLN n 1 198 PHE n 1 199 GLU n 1 200 TRP n 1 201 LEU n 1 202 GLU n 1 203 SER n 1 204 THR n 1 205 LEU n 1 206 ASN n 1 207 ASN n 1 208 SER n 1 209 GLN n 1 210 GLN n 1 211 ASN n 1 212 LYS n 1 213 GLU n 1 214 LYS n 1 215 VAL n 1 216 TYR n 1 217 ILE n 1 218 ILE n 1 219 ALA n 1 220 HIS n 1 221 VAL n 1 222 PRO n 1 223 VAL n 1 224 GLY n 1 225 TYR n 1 226 LEU n 1 227 PRO n 1 228 SER n 1 229 SER n 1 230 GLN n 1 231 ASN n 1 232 ILE n 1 233 THR n 1 234 ALA n 1 235 MET n 1 236 ARG n 1 237 GLU n 1 238 TYR n 1 239 TYR n 1 240 ASN n 1 241 GLU n 1 242 LYS n 1 243 LEU n 1 244 ILE n 1 245 ASP n 1 246 ILE n 1 247 PHE n 1 248 GLN n 1 249 LYS n 1 250 TYR n 1 251 SER n 1 252 ASP n 1 253 VAL n 1 254 ILE n 1 255 ALA n 1 256 GLY n 1 257 GLN n 1 258 PHE n 1 259 TYR n 1 260 GLY n 1 261 HIS n 1 262 THR n 1 263 HIS n 1 264 ARG n 1 265 ASP n 1 266 SER n 1 267 ILE n 1 268 MET n 1 269 VAL n 1 270 LEU n 1 271 SER n 1 272 ASP n 1 273 LYS n 1 274 LYS n 1 275 GLY n 1 276 SER n 1 277 PRO n 1 278 VAL n 1 279 ASN n 1 280 SER n 1 281 LEU n 1 282 PHE n 1 283 VAL n 1 284 ALA n 1 285 PRO n 1 286 ALA n 1 287 VAL n 1 288 THR n 1 289 PRO n 1 290 VAL n 1 291 LYS n 1 292 SER n 1 293 VAL n 1 294 LEU n 1 295 GLU n 1 296 LYS n 1 297 GLN n 1 298 THR n 1 299 ASN n 1 300 ASN n 1 301 PRO n 1 302 GLY n 1 303 ILE n 1 304 ARG n 1 305 LEU n 1 306 PHE n 1 307 GLN n 1 308 TYR n 1 309 ASP n 1 310 PRO n 1 311 ARG n 1 312 ASP n 1 313 TYR n 1 314 LYS n 1 315 LEU n 1 316 LEU n 1 317 ASP n 1 318 MET n 1 319 LEU n 1 320 GLN n 1 321 TYR n 1 322 TYR n 1 323 LEU n 1 324 ASN n 1 325 LEU n 1 326 THR n 1 327 GLU n 1 328 ALA n 1 329 ASN n 1 330 LEU n 1 331 LYS n 1 332 GLY n 1 333 GLU n 1 334 SER n 1 335 ILE n 1 336 TRP n 1 337 LYS n 1 338 LEU n 1 339 GLU n 1 340 TYR n 1 341 ILE n 1 342 LEU n 1 343 THR n 1 344 GLN n 1 345 THR n 1 346 TYR n 1 347 ASP n 1 348 ILE n 1 349 GLU n 1 350 ASP n 1 351 LEU n 1 352 GLN n 1 353 PRO n 1 354 GLU n 1 355 SER n 1 356 LEU n 1 357 TYR n 1 358 GLY n 1 359 LEU n 1 360 ALA n 1 361 LYS n 1 362 GLN n 1 363 PHE n 1 364 THR n 1 365 ILE n 1 366 LEU n 1 367 ASP n 1 368 SER n 1 369 LYS n 1 370 GLN n 1 371 PHE n 1 372 ILE n 1 373 LYS n 1 374 TYR n 1 375 TYR n 1 376 ASN n 1 377 TYR n 1 378 PHE n 1 379 PHE n 1 380 VAL n 1 381 SER n 1 382 TYR n 1 383 ASP n 1 384 SER n 1 385 SER n 1 386 VAL n 1 387 THR n 1 388 CYS n 1 389 ASP n 1 390 LYS n 1 391 THR n 1 392 CYS n 1 393 LYS n 1 394 ALA n 1 395 PHE n 1 396 GLN n 1 397 ILE n 1 398 CYS n 1 399 ALA n 1 400 ILE n 1 401 MET n 1 402 ASN n 1 403 LEU n 1 404 ASP n 1 405 ASN n 1 406 ILE n 1 407 SER n 1 408 TYR n 1 409 ALA n 1 410 ASP n 1 411 CYS n 1 412 LEU n 1 413 LYS n 1 414 GLN n 1 415 LEU n 1 416 TYR n 1 417 ILE n 1 418 LYS n 2 1 PRO n 2 2 PRO n 2 3 PRO n 2 4 ALA n 2 5 ILE n 2 6 GLY n 2 7 GLN n 2 8 PHE n 2 9 TRP n 2 10 HIS n 2 11 VAL n 2 12 THR n 2 13 ASP n 2 14 LEU n 2 15 HIS n 2 16 LEU n 2 17 ASP n 2 18 PRO n 2 19 THR n 2 20 TYR n 2 21 HIS n 2 22 ILE n 2 23 THR n 2 24 ASP n 2 25 ASP n 2 26 HIS n 2 27 THR n 2 28 LYS n 2 29 VAL n 2 30 CYS n 2 31 ALA n 2 32 SER n 2 33 SER n 2 34 LYS n 2 35 GLY n 2 36 ALA n 2 37 ASN n 2 38 ALA n 2 39 SER n 2 40 ASN n 2 41 PRO n 2 42 GLY n 2 43 PRO n 2 44 PHE n 2 45 GLY n 2 46 ASP n 2 47 VAL n 2 48 LEU n 2 49 CYS n 2 50 ASP n 2 51 SER n 2 52 PRO n 2 53 TYR n 2 54 GLN n 2 55 LEU n 2 56 ILE n 2 57 LEU n 2 58 SER n 2 59 ALA n 2 60 PHE n 2 61 ASP n 2 62 PHE n 2 63 ILE n 2 64 LYS n 2 65 ASN n 2 66 SER n 2 67 GLY n 2 68 GLN n 2 69 GLU n 2 70 ALA n 2 71 SER n 2 72 PHE n 2 73 MET n 2 74 ILE n 2 75 TRP n 2 76 THR n 2 77 GLY n 2 78 ASP n 2 79 SER n 2 80 PRO n 2 81 PRO n 2 82 HIS n 2 83 VAL n 2 84 PRO n 2 85 VAL n 2 86 PRO n 2 87 GLU n 2 88 LEU n 2 89 SER n 2 90 THR n 2 91 ASP n 2 92 THR n 2 93 VAL n 2 94 ILE n 2 95 ASN n 2 96 VAL n 2 97 ILE n 2 98 THR n 2 99 ASN n 2 100 MET n 2 101 THR n 2 102 THR n 2 103 THR n 2 104 ILE n 2 105 GLN n 2 106 SER n 2 107 LEU n 2 108 PHE n 2 109 PRO n 2 110 ASN n 2 111 LEU n 2 112 GLN n 2 113 VAL n 2 114 PHE n 2 115 PRO n 2 116 ALA n 2 117 LEU n 2 118 GLY n 2 119 ASN n 2 120 HIS n 2 121 ASP n 2 122 TYR n 2 123 TRP n 2 124 PRO n 2 125 GLN n 2 126 ASP n 2 127 GLN n 2 128 LEU n 2 129 PRO n 2 130 VAL n 2 131 VAL n 2 132 THR n 2 133 SER n 2 134 LYS n 2 135 VAL n 2 136 TYR n 2 137 ASN n 2 138 ALA n 2 139 VAL n 2 140 ALA n 2 141 ASN n 2 142 LEU n 2 143 TRP n 2 144 LYS n 2 145 PRO n 2 146 TRP n 2 147 LEU n 2 148 ASP n 2 149 GLU n 2 150 GLU n 2 151 ALA n 2 152 ILE n 2 153 SER n 2 154 THR n 2 155 LEU n 2 156 ARG n 2 157 LYS n 2 158 GLY n 2 159 GLY n 2 160 PHE n 2 161 TYR n 2 162 SER n 2 163 GLN n 2 164 LYS n 2 165 VAL n 2 166 THR n 2 167 THR n 2 168 ASN n 2 169 PRO n 2 170 ASN n 2 171 LEU n 2 172 ARG n 2 173 ILE n 2 174 ILE n 2 175 SER n 2 176 LEU n 2 177 ASN n 2 178 THR n 2 179 ASN n 2 180 LEU n 2 181 TYR n 2 182 TYR n 2 183 GLY n 2 184 PRO n 2 185 ASN n 2 186 ILE n 2 187 MET n 2 188 THR n 2 189 LEU n 2 190 ASN n 2 191 LYS n 2 192 THR n 2 193 ASP n 2 194 PRO n 2 195 ALA n 2 196 ASN n 2 197 GLN n 2 198 PHE n 2 199 GLU n 2 200 TRP n 2 201 LEU n 2 202 GLU n 2 203 SER n 2 204 THR n 2 205 LEU n 2 206 ASN n 2 207 ASN n 2 208 SER n 2 209 GLN n 2 210 GLN n 2 211 ASN n 2 212 LYS n 2 213 GLU n 2 214 LYS n 2 215 VAL n 2 216 TYR n 2 217 ILE n 2 218 ILE n 2 219 ALA n 2 220 HIS n 2 221 VAL n 2 222 PRO n 2 223 VAL n 2 224 GLY n 2 225 TYR n 2 226 LEU n 2 227 PRO n 2 228 SER n 2 229 SER n 2 230 GLN n 2 231 ASN n 2 232 ILE n 2 233 THR n 2 234 ALA n 2 235 MET n 2 236 ARG n 2 237 GLU n 2 238 TYR n 2 239 TYR n 2 240 ASN n 2 241 GLU n 2 242 LYS n 2 243 LEU n 2 244 ILE n 2 245 ASP n 2 246 ILE n 2 247 PHE n 2 248 GLN n 2 249 LYS n 2 250 TYR n 2 251 SER n 2 252 ASP n 2 253 VAL n 2 254 ILE n 2 255 ALA n 2 256 GLY n 2 257 GLN n 2 258 PHE n 2 259 TYR n 2 260 GLY n 2 261 HIS n 2 262 THR n 2 263 HIS n 2 264 ARG n 2 265 ASP n 2 266 SER n 2 267 ILE n 2 268 MET n 2 269 VAL n 2 270 LEU n 2 271 SER n 2 272 ASP n 2 273 LYS n 2 274 LYS n 2 275 GLY n 2 276 SER n 2 277 PRO n 2 278 VAL n 2 279 ASN n 2 280 SER n 2 281 LEU n 2 282 PHE n 2 283 VAL n 2 284 ALA n 2 285 PRO n 2 286 ALA n 2 287 VAL n 2 288 THR n 2 289 PRO n 2 290 VAL n 2 291 LYS n 2 292 SER n 2 293 VAL n 2 294 LEU n 2 295 GLU n 2 296 LYS n 2 297 GLN n 2 298 THR n 2 299 ASN n 2 300 ASN n 2 301 PRO n 2 302 GLY n 2 303 ILE n 2 304 ARG n 2 305 LEU n 2 306 PHE n 2 307 GLN n 2 308 TYR n 2 309 ASP n 2 310 PRO n 2 311 ARG n 2 312 ASP n 2 313 TYR n 2 314 LYS n 2 315 LEU n 2 316 LEU n 2 317 ASP n 2 318 MET n 2 319 LEU n 2 320 GLN n 2 321 TYR n 2 322 TYR n 2 323 LEU n 2 324 ASN n 2 325 LEU n 2 326 THR n 2 327 GLU n 2 328 ALA n 2 329 ASN n 2 330 LEU n 2 331 LYS n 2 332 GLY n 2 333 GLU n 2 334 SER n 2 335 ILE n 2 336 TRP n 2 337 LYS n 2 338 LEU n 2 339 GLU n 2 340 TYR n 2 341 ILE n 2 342 LEU n 2 343 THR n 2 344 GLN n 2 345 THR n 2 346 TYR n 2 347 ASP n 2 348 ILE n 2 349 GLU n 2 350 ASP n 2 351 LEU n 2 352 GLN n 2 353 PRO n 2 354 GLU n 2 355 SER n 2 356 LEU n 2 357 TYR n 2 358 GLY n 2 359 LEU n 2 360 ALA n 2 361 LYS n 2 362 GLN n 2 363 PHE n 2 364 THR n 2 365 ILE n 2 366 LEU n 2 367 ASP n 2 368 SER n 2 369 LYS n 2 370 GLN n 2 371 PHE n 2 372 ILE n 2 373 LYS n 2 374 TYR n 2 375 TYR n 2 376 ASN n 2 377 TYR n 2 378 PHE n 2 379 PHE n 2 380 VAL n 2 381 SER n 2 382 TYR n 2 383 ASP n 2 384 SER n 2 385 SER n 2 386 VAL n 2 387 THR n 2 388 CYS n 2 389 ASP n 2 390 LYS n 2 391 THR n 2 392 CYS n 2 393 LYS n 2 394 ALA n 2 395 PHE n 2 396 GLN n 2 397 ILE n 2 398 CYS n 2 399 ALA n 2 400 ILE n 2 401 MET n 2 402 ASN n 2 403 LEU n 2 404 ASP n 2 405 ASN n 2 406 ILE n 2 407 SER n 2 408 TYR n 2 409 ALA n 2 410 ASP n 2 411 CYS n 2 412 LEU n 2 413 LYS n 2 414 GLN n 2 415 LEU n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 418 Human ? 'SMPDL3A, ASML3A' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? Sf9 ? ? ? ? ? ? ? ? ? ? ? pFB-Sec-NH ? ? 2 1 sample 'Biological sequence' 1 415 Human ? 'SMPDL3A, ASML3A' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? pFB-SEC-NH ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP ASM3A_HUMAN Q92484 ? 1 ;PPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSP PHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGF YSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYN EKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQ YYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAI MNLDNISYADCLKQLYIK ; 33 2 UNP ASM3A_HUMAN Q92484 ? 2 ;PPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSP PHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGF YSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYN EKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQ YYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAI MNLDNISYADCLKQL ; 33 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5EBE A 1 ? 418 ? Q92484 33 ? 450 ? 33 450 2 2 5EBE B 1 ? 415 ? Q92484 33 ? 447 ? 33 447 3 2 5EBE C 1 ? 415 ? Q92484 33 ? 447 ? 33 447 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 C5P non-polymer . "CYTIDINE-5'-MONOPHOSPHATE" ? 'C9 H14 N3 O8 P' 323.197 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MLI non-polymer . 'MALONATE ION' ? 'C3 H2 O4 -2' 102.046 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 RP5 non-polymer . 5-O-phosphono-beta-D-ribofuranose '[(2R,3S,4S,5R)-3,4,5-TRIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN PHOSPHATE' 'C5 H11 O8 P' 230.110 SCN non-polymer . 'THIOCYANATE ION' ? 'C N S -1' 58.082 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5EBE _exptl.crystals_number ? _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 3.15 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 57.39 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH 7.2 _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details ;Crystal grew in 2.08 M disodium malonate pH 7.2, 0.23 M sodium thiocyanate and 0.01 M TCEP. But soaked at 2.08M disodium malonate pH 5 ; _exptl_crystal_grow.pdbx_pH_range 5-7.2 # _diffrn.ambient_environment ? _diffrn.ambient_temp 80 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'ADSC QUANTUM 315r' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2015-07-17 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9537 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'AUSTRALIAN SYNCHROTRON BEAMLINE MX2' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.9537 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline MX2 _diffrn_source.pdbx_synchrotron_site 'Australian Synchrotron' # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5EBE _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 3.0 _reflns.d_resolution_low 47.56 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all 40035 _reflns.number_obs 36234 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 99.7 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 3.7 _reflns.pdbx_Rmerge_I_obs 0.156 _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 6.3 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _reflns_shell.d_res_high 3.0 _reflns_shell.d_res_low 3.13 _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs 1.9 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all 99.9 _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs 0.60 _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy 3.7 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? # _refine.aniso_B[1][1] 0.50 _refine.aniso_B[1][2] 0.25 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][2] 0.50 _refine.aniso_B[2][3] 0.00 _refine.aniso_B[3][3] -1.61 _refine.B_iso_max ? _refine.B_iso_mean 40.035 _refine.B_iso_min ? _refine.correlation_coeff_Fo_to_Fc 0.945 _refine.correlation_coeff_Fo_to_Fc_free 0.908 _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 5EBE _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 3.00 _refine.ls_d_res_low 47.56 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 34411 _refine.ls_number_reflns_R_free 1790 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 99.63 _refine.ls_percent_reflns_R_free 4.9 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.25361 _refine.ls_R_factor_R_free 0.29481 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.25145 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details MASK _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model 5ebb _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R 0.424 _refine.pdbx_overall_ESU_R_Free 0.497 _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B ? _refine.overall_SU_ML 0.000 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id 1 _refine_hist.pdbx_number_atoms_protein 10016 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 268 _refine_hist.number_atoms_solvent 130 _refine_hist.number_atoms_total 10414 _refine_hist.d_res_high 3.00 _refine_hist.d_res_low 47.56 # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.d_res_high 3.000 _refine_ls_shell.d_res_low 3.078 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.number_reflns_R_free 121 _refine_ls_shell.number_reflns_R_work 2566 _refine_ls_shell.percent_reflns_obs 99.93 _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_obs ? _refine_ls_shell.R_factor_R_free 0.387 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.R_factor_R_work 0.361 _refine_ls_shell.redundancy_reflns_all ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.wR_factor_all ? _refine_ls_shell.wR_factor_obs ? _refine_ls_shell.wR_factor_R_free ? _refine_ls_shell.wR_factor_R_work ? _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.pdbx_phase_error ? _refine_ls_shell.pdbx_fsc_work ? _refine_ls_shell.pdbx_fsc_free ? # _struct.entry_id 5EBE _struct.title ;Structure of human sphingomyelinase phosphodiesterase like 3A (SMPDL3A) with 5' CMP ; _struct.pdbx_descriptor 'Acid sphingomyelinase-like phosphodiesterase 3a (E.C.3.1.4.-)' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5EBE _struct_keywords.text 'calcineurin like phosphodiesterase, binuclear metallophosphodiesterase, acid sphingomyelinase like, hydrolase' _struct_keywords.pdbx_keywords HYDROLASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 3 ? E N N 3 ? F N N 3 ? G N N 3 ? H N N 4 ? I N N 4 ? J N N 5 ? K N N 3 ? L N N 3 ? M N N 3 ? N N N 3 ? O N N 3 ? P N N 4 ? Q N N 4 ? R N N 6 ? S N N 6 ? T N N 7 ? U N N 8 ? V N N 3 ? W N N 3 ? X N N 3 ? Y N N 3 ? Z N N 4 ? AA N N 4 ? BA N N 5 ? CA N N 9 ? DA N N 9 ? EA N N 10 ? FA N N 10 ? GA N N 10 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 CYS A 30 ? LYS A 34 ? CYS A 62 LYS A 66 5 ? 5 HELX_P HELX_P2 AA2 PRO A 52 ? ASN A 65 ? PRO A 84 ASN A 97 1 ? 14 HELX_P HELX_P3 AA3 PRO A 84 ? LEU A 88 ? PRO A 116 LEU A 120 5 ? 5 HELX_P HELX_P4 AA4 SER A 89 ? PHE A 108 ? SER A 121 PHE A 140 1 ? 20 HELX_P HELX_P5 AA5 SER A 133 ? LYS A 144 ? SER A 165 LYS A 176 1 ? 12 HELX_P HELX_P6 AA6 PRO A 145 ? LEU A 147 ? PRO A 177 LEU A 179 5 ? 3 HELX_P HELX_P7 AA7 ASP A 148 ? GLY A 159 ? ASP A 180 GLY A 191 1 ? 12 HELX_P HELX_P8 AA8 ASN A 177 ? TYR A 182 ? ASN A 209 TYR A 214 5 ? 6 HELX_P HELX_P9 AA9 ASN A 185 ? LEU A 189 ? ASN A 217 LEU A 221 5 ? 5 HELX_P HELX_P10 AB1 ASP A 193 ? ALA A 195 ? ASP A 225 ALA A 227 5 ? 3 HELX_P HELX_P11 AB2 ASN A 196 ? ASN A 211 ? ASN A 228 ASN A 243 1 ? 16 HELX_P HELX_P12 AB3 ARG A 236 ? TYR A 250 ? ARG A 268 TYR A 282 1 ? 15 HELX_P HELX_P13 AB4 ASN A 324 ? GLY A 332 ? ASN A 356 GLY A 364 1 ? 9 HELX_P HELX_P14 AB5 LEU A 342 ? ASP A 347 ? LEU A 374 ASP A 379 1 ? 6 HELX_P HELX_P15 AB6 GLN A 352 ? ILE A 365 ? GLN A 384 ILE A 397 1 ? 14 HELX_P HELX_P16 AB7 SER A 368 ? PHE A 379 ? SER A 400 PHE A 411 1 ? 12 HELX_P HELX_P17 AB8 ASP A 389 ? ASN A 402 ? ASP A 421 ASN A 434 1 ? 14 HELX_P HELX_P18 AB9 ASP A 404 ? GLN A 414 ? ASP A 436 GLN A 446 1 ? 11 HELX_P HELX_P19 AC1 CYS B 30 ? LYS B 34 ? CYS B 62 LYS B 66 5 ? 5 HELX_P HELX_P20 AC2 PRO B 52 ? ASN B 65 ? PRO B 84 ASN B 97 1 ? 14 HELX_P HELX_P21 AC3 PRO B 84 ? LEU B 88 ? PRO B 116 LEU B 120 5 ? 5 HELX_P HELX_P22 AC4 SER B 89 ? PHE B 108 ? SER B 121 PHE B 140 1 ? 20 HELX_P HELX_P23 AC5 SER B 133 ? LYS B 144 ? SER B 165 LYS B 176 1 ? 12 HELX_P HELX_P24 AC6 ASP B 148 ? GLY B 158 ? ASP B 180 GLY B 190 1 ? 11 HELX_P HELX_P25 AC7 ASN B 177 ? TYR B 182 ? ASN B 209 TYR B 214 5 ? 6 HELX_P HELX_P26 AC8 ASP B 193 ? ALA B 195 ? ASP B 225 ALA B 227 5 ? 3 HELX_P HELX_P27 AC9 ASN B 196 ? ASN B 211 ? ASN B 228 ASN B 243 1 ? 16 HELX_P HELX_P28 AD1 ARG B 236 ? TYR B 250 ? ARG B 268 TYR B 282 1 ? 15 HELX_P HELX_P29 AD2 ASN B 324 ? GLY B 332 ? ASN B 356 GLY B 364 1 ? 9 HELX_P HELX_P30 AD3 LEU B 342 ? ASP B 347 ? LEU B 374 ASP B 379 1 ? 6 HELX_P HELX_P31 AD4 GLN B 352 ? THR B 364 ? GLN B 384 THR B 396 1 ? 13 HELX_P HELX_P32 AD5 SER B 368 ? PHE B 379 ? SER B 400 PHE B 411 1 ? 12 HELX_P HELX_P33 AD6 ASP B 389 ? MET B 401 ? ASP B 421 MET B 433 1 ? 13 HELX_P HELX_P34 AD7 ASP B 404 ? CYS B 411 ? ASP B 436 CYS B 443 1 ? 8 HELX_P HELX_P35 AD8 CYS C 30 ? LYS C 34 ? CYS C 62 LYS C 66 5 ? 5 HELX_P HELX_P36 AD9 PRO C 52 ? ASN C 65 ? PRO C 84 ASN C 97 1 ? 14 HELX_P HELX_P37 AE1 PRO C 84 ? LEU C 88 ? PRO C 116 LEU C 120 5 ? 5 HELX_P HELX_P38 AE2 SER C 89 ? PHE C 108 ? SER C 121 PHE C 140 1 ? 20 HELX_P HELX_P39 AE3 SER C 133 ? TRP C 143 ? SER C 165 TRP C 175 1 ? 11 HELX_P HELX_P40 AE4 LYS C 144 ? LEU C 147 ? LYS C 176 LEU C 179 5 ? 4 HELX_P HELX_P41 AE5 ASP C 148 ? GLY C 159 ? ASP C 180 GLY C 191 1 ? 12 HELX_P HELX_P42 AE6 ASN C 177 ? TYR C 181 ? ASN C 209 TYR C 213 5 ? 5 HELX_P HELX_P43 AE7 ASN C 185 ? LEU C 189 ? ASN C 217 LEU C 221 5 ? 5 HELX_P HELX_P44 AE8 ASP C 193 ? ALA C 195 ? ASP C 225 ALA C 227 5 ? 3 HELX_P HELX_P45 AE9 ASN C 196 ? ASN C 211 ? ASN C 228 ASN C 243 1 ? 16 HELX_P HELX_P46 AF1 ARG C 236 ? TYR C 250 ? ARG C 268 TYR C 282 1 ? 15 HELX_P HELX_P47 AF2 ASN C 324 ? GLY C 332 ? ASN C 356 GLY C 364 1 ? 9 HELX_P HELX_P48 AF3 LEU C 342 ? TYR C 346 ? LEU C 374 TYR C 378 1 ? 5 HELX_P HELX_P49 AF4 GLN C 352 ? ILE C 365 ? GLN C 384 ILE C 397 1 ? 14 HELX_P HELX_P50 AF5 SER C 368 ? TYR C 377 ? SER C 400 TYR C 409 1 ? 10 HELX_P HELX_P51 AF6 ASP C 389 ? ASN C 402 ? ASP C 421 ASN C 434 1 ? 14 HELX_P HELX_P52 AF7 ASP C 404 ? LEU C 412 ? ASP C 436 LEU C 444 1 ? 9 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 30 SG ? ? ? 1_555 A CYS 49 SG ? ? A CYS 62 A CYS 81 1_555 ? ? ? ? ? ? ? 2.064 ? disulf2 disulf ? ? A CYS 398 SG ? ? ? 1_555 A CYS 411 SG ? ? A CYS 430 A CYS 443 1_555 ? ? ? ? ? ? ? 2.063 ? disulf3 disulf ? ? B CYS 30 SG ? ? ? 1_555 B CYS 49 SG ? ? B CYS 62 B CYS 81 1_555 ? ? ? ? ? ? ? 2.048 ? disulf4 disulf ? ? C CYS 30 SG ? ? ? 1_555 C CYS 49 SG ? ? C CYS 62 C CYS 81 1_555 ? ? ? ? ? ? ? 2.069 ? disulf5 disulf ? ? C CYS 398 SG ? ? ? 1_555 C CYS 411 SG ? ? C CYS 430 C CYS 443 1_555 ? ? ? ? ? ? ? 2.045 ? metalc1 metalc ? ? A ASP 13 OD2 ? ? ? 1_555 I ZN . ZN ? ? A ASP 45 A ZN 606 1_555 ? ? ? ? ? ? ? 2.399 ? metalc2 metalc ? ? A HIS 15 NE2 ? ? ? 1_555 I ZN . ZN ? ? A HIS 47 A ZN 606 1_555 ? ? ? ? ? ? ? 2.102 ? covale1 covale one ? A ASN 37 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 69 A NAG 601 1_555 ? ? ? ? ? ? ? 1.307 ? metalc3 metalc ? ? A ASP 78 OD2 ? ? ? 1_555 H ZN . ZN ? ? A ASP 110 A ZN 605 1_555 ? ? ? ? ? ? ? 2.228 ? metalc4 metalc ? ? A ASP 78 OD2 ? ? ? 1_555 I ZN . ZN ? ? A ASP 110 A ZN 606 1_555 ? ? ? ? ? ? ? 2.374 ? covale2 covale one ? A ASN 99 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 131 A NAG 602 1_555 ? ? ? ? ? ? ? 1.312 ? metalc5 metalc ? ? A ASN 119 OD1 ? ? ? 1_555 H ZN . ZN ? ? A ASN 151 A ZN 605 1_555 ? ? ? ? ? ? ? 2.235 ? metalc6 metalc ? ? A HIS 220 NE2 ? ? ? 1_555 H ZN . ZN ? ? A HIS 252 A ZN 605 1_555 ? ? ? ? ? ? ? 2.072 ? covale3 covale one ? A ASN 231 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 263 A NAG 603 1_555 ? ? ? ? ? ? ? 1.301 ? metalc7 metalc ? ? A HIS 261 ND1 ? ? ? 1_555 H ZN . ZN ? ? A HIS 293 A ZN 605 1_555 ? ? ? ? ? ? ? 2.331 ? metalc8 metalc ? ? A HIS 263 NE2 ? ? ? 1_555 I ZN . ZN ? ? A HIS 295 A ZN 606 1_555 ? ? ? ? ? ? ? 2.303 ? metalc9 metalc ? ? B ASP 13 OD2 ? ? ? 1_555 P ZN . ZN ? ? B ASP 45 B ZN 606 1_555 ? ? ? ? ? ? ? 2.296 ? metalc10 metalc ? ? B HIS 15 NE2 ? ? ? 1_555 P ZN . ZN ? ? B HIS 47 B ZN 606 1_555 ? ? ? ? ? ? ? 2.395 ? covale4 covale one ? B ASN 37 ND2 ? ? ? 1_555 K NAG . C1 ? ? B ASN 69 B NAG 601 1_555 ? ? ? ? ? ? ? 1.304 ? metalc11 metalc ? ? B ASP 78 OD2 ? ? ? 1_555 P ZN . ZN ? ? B ASP 110 B ZN 606 1_555 ? ? ? ? ? ? ? 2.302 ? metalc12 metalc ? ? B ASP 78 OD2 ? ? ? 1_555 Q ZN . ZN ? ? B ASP 110 B ZN 607 1_555 ? ? ? ? ? ? ? 2.382 ? covale5 covale one ? B ASN 99 ND2 ? ? ? 1_555 L NAG . C1 ? ? B ASN 131 B NAG 602 1_555 ? ? ? ? ? ? ? 1.311 ? metalc13 metalc ? ? B ASN 119 OD1 ? ? ? 1_555 Q ZN . ZN ? ? B ASN 151 B ZN 607 1_555 ? ? ? ? ? ? ? 2.491 ? metalc14 metalc ? ? B HIS 220 NE2 ? ? ? 1_555 Q ZN . ZN ? ? B HIS 252 B ZN 607 1_555 ? ? ? ? ? ? ? 2.215 ? covale6 covale one ? B ASN 231 ND2 ? ? ? 1_555 N NAG . C1 ? ? B ASN 263 B NAG 604 1_555 ? ? ? ? ? ? ? 1.275 ? metalc15 metalc ? ? B HIS 261 ND1 ? ? ? 1_555 Q ZN . ZN ? ? B HIS 293 B ZN 607 1_555 ? ? ? ? ? ? ? 2.698 ? metalc16 metalc ? ? B HIS 263 NE2 ? ? ? 1_555 P ZN . ZN ? ? B HIS 295 B ZN 606 1_555 ? ? ? ? ? ? ? 2.406 ? covale7 covale one ? B ASN 324 ND2 ? ? ? 1_555 O NAG . C1 ? ? B ASN 356 B NAG 605 1_555 ? ? ? ? ? ? ? 1.322 ? metalc17 metalc ? ? C ASP 13 OD2 ? ? ? 1_555 AA ZN . ZN ? ? C ASP 45 C ZN 606 1_555 ? ? ? ? ? ? ? 2.144 ? metalc18 metalc ? ? C HIS 15 NE2 ? ? ? 1_555 AA ZN . ZN ? ? C HIS 47 C ZN 606 1_555 ? ? ? ? ? ? ? 2.330 ? covale8 covale one ? C ASN 37 ND2 ? ? ? 1_555 V NAG . C1 ? ? C ASN 69 C NAG 601 1_555 ? ? ? ? ? ? ? 1.563 ? metalc19 metalc ? ? C ASP 78 OD2 ? ? ? 1_555 AA ZN . ZN ? ? C ASP 110 C ZN 606 1_555 ? ? ? ? ? ? ? 2.591 ? metalc20 metalc ? ? C ASP 78 OD2 ? ? ? 1_555 Z ZN . ZN ? ? C ASP 110 C ZN 605 1_555 ? ? ? ? ? ? ? 2.406 ? covale9 covale one ? C ASN 99 ND2 ? ? ? 1_555 W NAG . C1 ? ? C ASN 131 C NAG 602 1_555 ? ? ? ? ? ? ? 1.303 ? metalc21 metalc ? ? C ASN 119 OD1 ? ? ? 1_555 Z ZN . ZN ? ? C ASN 151 C ZN 605 1_555 ? ? ? ? ? ? ? 2.274 ? metalc22 metalc ? ? C HIS 220 NE2 ? ? ? 1_555 Z ZN . ZN ? ? C HIS 252 C ZN 605 1_555 ? ? ? ? ? ? ? 1.895 ? covale10 covale one ? C ASN 231 ND2 ? ? ? 1_555 X NAG . C1 ? ? C ASN 263 C NAG 603 1_555 ? ? ? ? ? ? ? 1.298 ? metalc23 metalc ? ? C HIS 261 ND1 ? ? ? 1_555 Z ZN . ZN ? ? C HIS 293 C ZN 605 1_555 ? ? ? ? ? ? ? 2.510 ? metalc24 metalc ? ? C HIS 263 NE2 ? ? ? 1_555 AA ZN . ZN ? ? C HIS 295 C ZN 606 1_555 ? ? ? ? ? ? ? 2.423 ? covale11 covale one ? C ASN 324 ND2 ? ? ? 1_555 Y NAG . C1 ? ? C ASN 356 C NAG 604 1_555 ? ? ? ? ? ? ? 1.340 ? metalc25 metalc ? ? H ZN . ZN ? ? ? 1_555 J C5P . O1P ? ? A ZN 605 A C5P 607 1_555 ? ? ? ? ? ? ? 2.036 ? metalc26 metalc ? ? I ZN . ZN ? ? ? 1_555 J C5P . O2P ? ? A ZN 606 A C5P 607 1_555 ? ? ? ? ? ? ? 1.715 ? covale12 covale both ? L NAG . O4 ? ? ? 1_555 M NAG . C1 ? ? B NAG 602 B NAG 603 1_555 ? ? ? ? ? ? ? 1.349 ? metalc27 metalc ? ? P ZN . ZN ? ? ? 1_555 U RP5 . O3X ? ? B ZN 606 B RP5 611 1_555 ? ? ? ? ? ? ? 2.277 ? metalc28 metalc ? ? Z ZN . ZN ? ? ? 1_555 BA C5P . O2P ? ? C ZN 605 C C5P 607 1_555 ? ? ? ? ? ? ? 1.941 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 TRP 123 A . ? TRP 155 A PRO 124 A ? PRO 156 A 1 -2.78 2 LEU 415 A . ? LEU 447 A TYR 416 A ? TYR 448 A 1 -3.55 3 TRP 123 B . ? TRP 155 B PRO 124 B ? PRO 156 B 1 -6.57 4 TRP 123 C . ? TRP 155 C PRO 124 C ? PRO 156 C 1 2.14 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 6 ? AA2 ? 6 ? AA3 ? 6 ? AA4 ? 6 ? AA5 ? 6 ? AA6 ? 6 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? parallel AA1 2 3 ? parallel AA1 3 4 ? anti-parallel AA1 4 5 ? anti-parallel AA1 5 6 ? anti-parallel AA2 1 2 ? anti-parallel AA2 2 3 ? parallel AA2 3 4 ? parallel AA2 4 5 ? parallel AA2 5 6 ? anti-parallel AA3 1 2 ? parallel AA3 2 3 ? parallel AA3 3 4 ? anti-parallel AA3 4 5 ? anti-parallel AA3 5 6 ? anti-parallel AA4 1 2 ? anti-parallel AA4 2 3 ? parallel AA4 3 4 ? parallel AA4 4 5 ? parallel AA4 5 6 ? anti-parallel AA5 1 2 ? parallel AA5 2 3 ? parallel AA5 3 4 ? anti-parallel AA5 4 5 ? anti-parallel AA5 5 6 ? anti-parallel AA6 1 2 ? anti-parallel AA6 2 3 ? parallel AA6 3 4 ? parallel AA6 4 5 ? parallel AA6 5 6 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 GLN A 112 ? PRO A 115 ? GLN A 144 PRO A 147 AA1 2 PHE A 72 ? TRP A 75 ? PHE A 104 TRP A 107 AA1 3 GLY A 6 ? VAL A 11 ? GLY A 38 VAL A 43 AA1 4 GLY A 302 ? ASP A 309 ? GLY A 334 ASP A 341 AA1 5 LYS A 314 ? LEU A 323 ? LYS A 346 LEU A 355 AA1 6 TRP A 336 ? ILE A 341 ? TRP A 368 ILE A 373 AA2 1 TYR A 161 ? VAL A 165 ? TYR A 193 VAL A 197 AA2 2 ASN A 168 ? LEU A 176 ? ASN A 200 LEU A 208 AA2 3 LYS A 214 ? ALA A 219 ? LYS A 246 ALA A 251 AA2 4 ILE A 254 ? TYR A 259 ? ILE A 286 TYR A 291 AA2 5 PRO A 277 ? VAL A 283 ? PRO A 309 VAL A 315 AA2 6 SER A 266 ? SER A 271 ? SER A 298 SER A 303 AA3 1 GLN B 112 ? ALA B 116 ? GLN B 144 ALA B 148 AA3 2 PHE B 72 ? THR B 76 ? PHE B 104 THR B 108 AA3 3 GLY B 6 ? VAL B 11 ? GLY B 38 VAL B 43 AA3 4 GLY B 302 ? TYR B 308 ? GLY B 334 TYR B 340 AA3 5 LEU B 315 ? LEU B 323 ? LEU B 347 LEU B 355 AA3 6 TRP B 336 ? ILE B 341 ? TRP B 368 ILE B 373 AA4 1 TYR B 161 ? VAL B 165 ? TYR B 193 VAL B 197 AA4 2 ASN B 168 ? SER B 175 ? ASN B 200 SER B 207 AA4 3 LYS B 214 ? ILE B 218 ? LYS B 246 ILE B 250 AA4 4 ILE B 254 ? TYR B 259 ? ILE B 286 TYR B 291 AA4 5 PRO B 277 ? VAL B 283 ? PRO B 309 VAL B 315 AA4 6 SER B 266 ? SER B 271 ? SER B 298 SER B 303 AA5 1 VAL C 113 ? PRO C 115 ? VAL C 145 PRO C 147 AA5 2 PHE C 72 ? TRP C 75 ? PHE C 104 TRP C 107 AA5 3 GLY C 6 ? VAL C 11 ? GLY C 38 VAL C 43 AA5 4 GLY C 302 ? TYR C 308 ? GLY C 334 TYR C 340 AA5 5 LEU C 315 ? TYR C 322 ? LEU C 347 TYR C 354 AA5 6 LYS C 337 ? ILE C 341 ? LYS C 369 ILE C 373 AA6 1 TYR C 161 ? VAL C 165 ? TYR C 193 VAL C 197 AA6 2 ASN C 168 ? LEU C 176 ? ASN C 200 LEU C 208 AA6 3 LYS C 214 ? ALA C 219 ? LYS C 246 ALA C 251 AA6 4 ILE C 254 ? TYR C 259 ? ILE C 286 TYR C 291 AA6 5 PRO C 277 ? VAL C 283 ? PRO C 309 VAL C 315 AA6 6 SER C 266 ? SER C 271 ? SER C 298 SER C 303 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 O PHE A 114 ? O PHE A 146 N TRP A 75 ? N TRP A 107 AA1 2 3 O ILE A 74 ? O ILE A 106 N VAL A 11 ? N VAL A 43 AA1 3 4 N PHE A 8 ? N PHE A 40 O PHE A 306 ? O PHE A 338 AA1 4 5 N ILE A 303 ? N ILE A 335 O TYR A 321 ? O TYR A 353 AA1 5 6 N GLN A 320 ? N GLN A 352 O GLU A 339 ? O GLU A 371 AA2 1 2 N GLN A 163 ? N GLN A 195 O ILE A 173 ? O ILE A 205 AA2 2 3 N ARG A 172 ? N ARG A 204 O LYS A 214 ? O LYS A 246 AA2 3 4 N VAL A 215 ? N VAL A 247 O ALA A 255 ? O ALA A 287 AA2 4 5 N TYR A 259 ? N TYR A 291 O PHE A 282 ? O PHE A 314 AA2 5 6 O VAL A 278 ? O VAL A 310 N LEU A 270 ? N LEU A 302 AA3 1 2 O ALA B 116 ? O ALA B 148 N TRP B 75 ? N TRP B 107 AA3 2 3 O ILE B 74 ? O ILE B 106 N TRP B 9 ? N TRP B 41 AA3 3 4 N PHE B 8 ? N PHE B 40 O PHE B 306 ? O PHE B 338 AA3 4 5 N LEU B 305 ? N LEU B 337 O LEU B 319 ? O LEU B 351 AA3 5 6 N GLN B 320 ? N GLN B 352 O GLU B 339 ? O GLU B 371 AA4 1 2 N VAL B 165 ? N VAL B 197 O LEU B 171 ? O LEU B 203 AA4 2 3 N ARG B 172 ? N ARG B 204 O LYS B 214 ? O LYS B 246 AA4 3 4 N ILE B 217 ? N ILE B 249 O PHE B 258 ? O PHE B 290 AA4 4 5 N GLN B 257 ? N GLN B 289 O SER B 280 ? O SER B 312 AA4 5 6 O VAL B 278 ? O VAL B 310 N LEU B 270 ? N LEU B 302 AA5 1 2 O PHE C 114 ? O PHE C 146 N MET C 73 ? N MET C 105 AA5 2 3 O ILE C 74 ? O ILE C 106 N VAL C 11 ? N VAL C 43 AA5 3 4 N GLY C 6 ? N GLY C 38 O TYR C 308 ? O TYR C 340 AA5 4 5 N GLN C 307 ? N GLN C 339 O ASP C 317 ? O ASP C 349 AA5 5 6 N TYR C 322 ? N TYR C 354 O LYS C 337 ? O LYS C 369 AA6 1 2 N GLN C 163 ? N GLN C 195 O ILE C 173 ? O ILE C 205 AA6 2 3 N LEU C 176 ? N LEU C 208 O ILE C 218 ? O ILE C 250 AA6 3 4 N VAL C 215 ? N VAL C 247 O ALA C 255 ? O ALA C 287 AA6 4 5 N TYR C 259 ? N TYR C 291 O PHE C 282 ? O PHE C 314 AA6 5 6 O VAL C 278 ? O VAL C 310 N LEU C 270 ? N LEU C 302 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A NAG 604 ? 3 'binding site for residue NAG A 604' AC2 Software A ZN 605 ? 6 'binding site for residue ZN A 605' AC3 Software A ZN 606 ? 6 'binding site for residue ZN A 606' AC4 Software A C5P 607 ? 15 'binding site for residue C5P A 607' AC5 Software B ZN 606 ? 6 'binding site for residue ZN B 606' AC6 Software B ZN 607 ? 6 'binding site for residue ZN B 607' AC7 Software B GOL 609 ? 2 'binding site for residue GOL B 609' AC8 Software B MLI 610 ? 4 'binding site for residue MLI B 610' AC9 Software B RP5 611 ? 9 'binding site for residue RP5 B 611' AD1 Software C ZN 605 ? 5 'binding site for residue ZN C 605' AD2 Software C ZN 606 ? 5 'binding site for residue ZN C 606' AD3 Software C C5P 607 ? 14 'binding site for residue C5P C 607' AD4 Software A NAG 601 ? 2 'binding site for Mono-Saccharide NAG A 601 bound to ASN A 69' AD5 Software A NAG 602 ? 2 'binding site for Mono-Saccharide NAG A 602 bound to ASN A 131' AD6 Software A NAG 603 ? 1 'binding site for Mono-Saccharide NAG A 603 bound to ASN A 263' AD7 Software B NAG 601 ? 4 'binding site for Mono-Saccharide NAG B 601 bound to ASN B 69' AD8 Software B ASN 131 ? 4 'binding site for Poly-Saccharide residues NAG B 602 through NAG B 603 bound to ASN B 131' AD9 Software B NAG 604 ? 1 'binding site for Mono-Saccharide NAG B 604 bound to ASN B 263' AE1 Software B NAG 605 ? 4 'binding site for Mono-Saccharide NAG B 605 bound to ASN B 356' AE2 Software C NAG 601 ? 2 'binding site for Mono-Saccharide NAG C 601 bound to ASN C 69' AE3 Software C NAG 602 ? 1 'binding site for Mono-Saccharide NAG C 602 bound to ASN C 131' AE4 Software C NAG 603 ? 1 'binding site for Mono-Saccharide NAG C 603 bound to ASN C 263' AE5 Software C NAG 604 ? 4 'binding site for Mono-Saccharide NAG C 604 bound to ASN C 356' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 3 TYR A 322 ? TYR A 354 . ? 1_555 ? 2 AC1 3 ASN A 324 ? ASN A 356 . ? 1_555 ? 3 AC1 3 LYS A 337 ? LYS A 369 . ? 1_555 ? 4 AC2 6 ASP A 78 ? ASP A 110 . ? 1_555 ? 5 AC2 6 ASN A 119 ? ASN A 151 . ? 1_555 ? 6 AC2 6 HIS A 220 ? HIS A 252 . ? 1_555 ? 7 AC2 6 HIS A 261 ? HIS A 293 . ? 1_555 ? 8 AC2 6 ZN I . ? ZN A 606 . ? 1_555 ? 9 AC2 6 C5P J . ? C5P A 607 . ? 1_555 ? 10 AC3 6 ASP A 13 ? ASP A 45 . ? 1_555 ? 11 AC3 6 HIS A 15 ? HIS A 47 . ? 1_555 ? 12 AC3 6 ASP A 78 ? ASP A 110 . ? 1_555 ? 13 AC3 6 HIS A 263 ? HIS A 295 . ? 1_555 ? 14 AC3 6 ZN H . ? ZN A 605 . ? 1_555 ? 15 AC3 6 C5P J . ? C5P A 607 . ? 1_555 ? 16 AC4 15 HIS A 15 ? HIS A 47 . ? 1_555 ? 17 AC4 15 ASP A 78 ? ASP A 110 . ? 1_555 ? 18 AC4 15 HIS A 82 ? HIS A 114 . ? 1_555 ? 19 AC4 15 ASN A 119 ? ASN A 151 . ? 1_555 ? 20 AC4 15 HIS A 120 ? HIS A 152 . ? 1_555 ? 21 AC4 15 HIS A 261 ? HIS A 293 . ? 1_555 ? 22 AC4 15 THR A 262 ? THR A 294 . ? 1_555 ? 23 AC4 15 HIS A 263 ? HIS A 295 . ? 1_555 ? 24 AC4 15 ARG A 264 ? ARG A 296 . ? 1_555 ? 25 AC4 15 VAL A 290 ? VAL A 322 . ? 1_555 ? 26 AC4 15 LYS A 291 ? LYS A 323 . ? 1_555 ? 27 AC4 15 GLU A 295 ? GLU A 327 . ? 1_555 ? 28 AC4 15 ZN H . ? ZN A 605 . ? 1_555 ? 29 AC4 15 ZN I . ? ZN A 606 . ? 1_555 ? 30 AC4 15 HOH EA . ? HOH A 716 . ? 1_555 ? 31 AC5 6 ASP B 13 ? ASP B 45 . ? 1_555 ? 32 AC5 6 HIS B 15 ? HIS B 47 . ? 1_555 ? 33 AC5 6 ASP B 78 ? ASP B 110 . ? 1_555 ? 34 AC5 6 HIS B 263 ? HIS B 295 . ? 1_555 ? 35 AC5 6 ZN Q . ? ZN B 607 . ? 1_555 ? 36 AC5 6 RP5 U . ? RP5 B 611 . ? 1_555 ? 37 AC6 6 ASP B 78 ? ASP B 110 . ? 1_555 ? 38 AC6 6 ASN B 119 ? ASN B 151 . ? 1_555 ? 39 AC6 6 HIS B 220 ? HIS B 252 . ? 1_555 ? 40 AC6 6 HIS B 261 ? HIS B 293 . ? 1_555 ? 41 AC6 6 ZN P . ? ZN B 606 . ? 1_555 ? 42 AC6 6 RP5 U . ? RP5 B 611 . ? 1_555 ? 43 AC7 2 ARG B 156 ? ARG B 188 . ? 1_555 ? 44 AC7 2 HOH FA . ? HOH B 730 . ? 1_555 ? 45 AC8 4 SER B 133 ? SER B 165 . ? 1_555 ? 46 AC8 4 LYS B 134 ? LYS B 166 . ? 1_555 ? 47 AC8 4 ASN B 137 ? ASN B 169 . ? 1_555 ? 48 AC8 4 LYS C 191 ? LYS C 223 . ? 6_654 ? 49 AC9 9 HIS B 15 ? HIS B 47 . ? 1_555 ? 50 AC9 9 ASP B 78 ? ASP B 110 . ? 1_555 ? 51 AC9 9 HIS B 82 ? HIS B 114 . ? 1_555 ? 52 AC9 9 ASN B 119 ? ASN B 151 . ? 1_555 ? 53 AC9 9 HIS B 120 ? HIS B 152 . ? 1_555 ? 54 AC9 9 HIS B 261 ? HIS B 293 . ? 1_555 ? 55 AC9 9 HIS B 263 ? HIS B 295 . ? 1_555 ? 56 AC9 9 ZN P . ? ZN B 606 . ? 1_555 ? 57 AC9 9 ZN Q . ? ZN B 607 . ? 1_555 ? 58 AD1 5 ASP C 78 ? ASP C 110 . ? 1_555 ? 59 AD1 5 ASN C 119 ? ASN C 151 . ? 1_555 ? 60 AD1 5 HIS C 220 ? HIS C 252 . ? 1_555 ? 61 AD1 5 HIS C 261 ? HIS C 293 . ? 1_555 ? 62 AD1 5 C5P BA . ? C5P C 607 . ? 1_555 ? 63 AD2 5 ASP C 13 ? ASP C 45 . ? 1_555 ? 64 AD2 5 HIS C 15 ? HIS C 47 . ? 1_555 ? 65 AD2 5 ASP C 78 ? ASP C 110 . ? 1_555 ? 66 AD2 5 HIS C 263 ? HIS C 295 . ? 1_555 ? 67 AD2 5 C5P BA . ? C5P C 607 . ? 1_555 ? 68 AD3 14 HIS C 15 ? HIS C 47 . ? 1_555 ? 69 AD3 14 LYS C 34 ? LYS C 66 . ? 1_555 ? 70 AD3 14 ASP C 78 ? ASP C 110 . ? 1_555 ? 71 AD3 14 HIS C 82 ? HIS C 114 . ? 1_555 ? 72 AD3 14 ASN C 119 ? ASN C 151 . ? 1_555 ? 73 AD3 14 HIS C 120 ? HIS C 152 . ? 1_555 ? 74 AD3 14 HIS C 220 ? HIS C 252 . ? 1_555 ? 75 AD3 14 HIS C 261 ? HIS C 293 . ? 1_555 ? 76 AD3 14 THR C 262 ? THR C 294 . ? 1_555 ? 77 AD3 14 HIS C 263 ? HIS C 295 . ? 1_555 ? 78 AD3 14 GLU C 295 ? GLU C 327 . ? 1_555 ? 79 AD3 14 ZN Z . ? ZN C 605 . ? 1_555 ? 80 AD3 14 ZN AA . ? ZN C 606 . ? 1_555 ? 81 AD3 14 HOH GA . ? HOH C 725 . ? 1_555 ? 82 AD4 2 ASN A 37 ? ASN A 69 . ? 1_555 ? 83 AD4 2 THR A 387 ? THR A 419 . ? 4_555 ? 84 AD5 2 ASN A 99 ? ASN A 131 . ? 1_555 ? 85 AD5 2 HOH EA . ? HOH A 707 . ? 1_555 ? 86 AD6 1 ASN A 231 ? ASN A 263 . ? 1_555 ? 87 AD7 4 THR B 27 ? THR B 59 . ? 1_555 ? 88 AD7 4 ASN B 37 ? ASN B 69 . ? 1_555 ? 89 AD7 4 ILE C 372 ? ILE C 404 . ? 4_545 ? 90 AD7 4 THR C 387 ? THR C 419 . ? 4_545 ? 91 AD8 4 PRO B 18 ? PRO B 50 . ? 1_555 ? 92 AD8 4 TYR B 53 ? TYR B 85 . ? 1_555 ? 93 AD8 4 ASN B 99 ? ASN B 131 . ? 1_555 ? 94 AD8 4 HOH FA . ? HOH B 709 . ? 1_555 ? 95 AD9 1 ASN B 231 ? ASN B 263 . ? 1_555 ? 96 AE1 4 LYS A 212 ? LYS A 244 . ? 1_555 ? 97 AE1 4 TYR B 322 ? TYR B 354 . ? 1_555 ? 98 AE1 4 ASN B 324 ? ASN B 356 . ? 1_555 ? 99 AE1 4 SER B 381 ? SER B 413 . ? 1_555 ? 100 AE2 2 THR B 387 ? THR B 419 . ? 4_655 ? 101 AE2 2 ASN C 37 ? ASN C 69 . ? 1_555 ? 102 AE3 1 ASN C 99 ? ASN C 131 . ? 1_555 ? 103 AE4 1 ASN C 231 ? ASN C 263 . ? 1_555 ? 104 AE5 4 ASN C 324 ? ASN C 356 . ? 1_555 ? 105 AE5 4 SER C 381 ? SER C 413 . ? 1_555 ? 106 AE5 4 TYR C 382 ? TYR C 414 . ? 1_555 ? 107 AE5 4 SER C 384 ? SER C 416 . ? 1_555 ? # _atom_sites.entry_id 5EBE _atom_sites.fract_transf_matrix[1][1] 0.006773 _atom_sites.fract_transf_matrix[1][2] 0.003910 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.007820 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007028 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O P S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . PRO A 1 1 ? 45.214 -10.179 12.927 1.00 89.75 ? 33 PRO A N 1 ATOM 2 C CA . PRO A 1 1 ? 45.531 -9.226 11.856 1.00 86.61 ? 33 PRO A CA 1 ATOM 3 C C . PRO A 1 1 ? 45.820 -9.907 10.494 1.00 82.06 ? 33 PRO A C 1 ATOM 4 O O . PRO A 1 1 ? 46.472 -10.966 10.471 1.00 76.84 ? 33 PRO A O 1 ATOM 5 C CB . PRO A 1 1 ? 46.756 -8.494 12.414 1.00 86.47 ? 33 PRO A CB 1 ATOM 6 C CG . PRO A 1 1 ? 46.543 -8.512 13.912 1.00 88.12 ? 33 PRO A CG 1 ATOM 7 C CD . PRO A 1 1 ? 45.630 -9.673 14.252 1.00 87.44 ? 33 PRO A CD 1 ATOM 8 N N . PRO A 1 2 ? 45.318 -9.320 9.373 1.00 76.97 ? 34 PRO A N 1 ATOM 9 C CA . PRO A 1 2 ? 45.398 -9.944 8.041 1.00 69.89 ? 34 PRO A CA 1 ATOM 10 C C . PRO A 1 2 ? 46.470 -9.326 7.156 1.00 62.92 ? 34 PRO A C 1 ATOM 11 O O . PRO A 1 2 ? 46.610 -8.107 7.145 1.00 64.11 ? 34 PRO A O 1 ATOM 12 C CB . PRO A 1 2 ? 44.024 -9.643 7.452 1.00 70.14 ? 34 PRO A CB 1 ATOM 13 C CG . PRO A 1 2 ? 43.677 -8.301 8.047 1.00 75.24 ? 34 PRO A CG 1 ATOM 14 C CD . PRO A 1 2 ? 44.507 -8.089 9.301 1.00 75.26 ? 34 PRO A CD 1 ATOM 15 N N . PRO A 1 3 ? 47.211 -10.155 6.401 1.00 57.92 ? 35 PRO A N 1 ATOM 16 C CA . PRO A 1 3 ? 48.456 -9.683 5.750 1.00 53.80 ? 35 PRO A CA 1 ATOM 17 C C . PRO A 1 3 ? 48.281 -8.906 4.425 1.00 47.77 ? 35 PRO A C 1 ATOM 18 O O . PRO A 1 3 ? 49.157 -8.136 4.027 1.00 41.55 ? 35 PRO A O 1 ATOM 19 C CB . PRO A 1 3 ? 49.269 -10.979 5.553 1.00 54.61 ? 35 PRO A CB 1 ATOM 20 C CG . PRO A 1 3 ? 48.331 -12.119 5.814 1.00 56.78 ? 35 PRO A CG 1 ATOM 21 C CD . PRO A 1 3 ? 46.959 -11.579 6.116 1.00 58.46 ? 35 PRO A CD 1 ATOM 22 N N . ALA A 1 4 ? 47.164 -9.131 3.747 1.00 47.08 ? 36 ALA A N 1 ATOM 23 C CA . ALA A 1 4 ? 46.744 -8.282 2.641 1.00 45.80 ? 36 ALA A CA 1 ATOM 24 C C . ALA A 1 4 ? 45.214 -8.256 2.599 1.00 45.01 ? 36 ALA A C 1 ATOM 25 O O . ALA A 1 4 ? 44.539 -9.202 3.025 1.00 43.21 ? 36 ALA A O 1 ATOM 26 C CB . ALA A 1 4 ? 47.324 -8.769 1.316 1.00 44.42 ? 36 ALA A CB 1 ATOM 27 N N . ILE A 1 5 ? 44.696 -7.144 2.089 1.00 44.28 ? 37 ILE A N 1 ATOM 28 C CA . ILE A 1 5 ? 43.265 -6.851 2.018 1.00 40.56 ? 37 ILE A CA 1 ATOM 29 C C . ILE A 1 5 ? 42.715 -7.125 0.613 1.00 37.66 ? 37 ILE A C 1 ATOM 30 O O . ILE A 1 5 ? 43.168 -6.534 -0.377 1.00 33.72 ? 37 ILE A O 1 ATOM 31 C CB . ILE A 1 5 ? 43.019 -5.353 2.342 1.00 38.66 ? 37 ILE A CB 1 ATOM 32 C CG1 . ILE A 1 5 ? 43.553 -5.002 3.737 1.00 37.20 ? 37 ILE A CG1 1 ATOM 33 C CG2 . ILE A 1 5 ? 41.547 -5.002 2.203 1.00 38.87 ? 37 ILE A CG2 1 ATOM 34 C CD1 . ILE A 1 5 ? 43.070 -5.919 4.838 1.00 36.31 ? 37 ILE A CD1 1 ATOM 35 N N . GLY A 1 6 ? 41.728 -8.011 0.539 1.00 36.85 ? 38 GLY A N 1 ATOM 36 C CA . GLY A 1 6 ? 40.935 -8.187 -0.685 1.00 35.20 ? 38 GLY A CA 1 ATOM 37 C C . GLY A 1 6 ? 39.870 -7.109 -0.790 1.00 32.50 ? 38 GLY A C 1 ATOM 38 O O . GLY A 1 6 ? 39.293 -6.717 0.222 1.00 31.27 ? 38 GLY A O 1 ATOM 39 N N . GLN A 1 7 ? 39.607 -6.630 -2.003 1.00 30.41 ? 39 GLN A N 1 ATOM 40 C CA . GLN A 1 7 ? 38.615 -5.575 -2.213 1.00 28.58 ? 39 GLN A CA 1 ATOM 41 C C . GLN A 1 7 ? 37.794 -5.874 -3.447 1.00 28.65 ? 39 GLN A C 1 ATOM 42 O O . GLN A 1 7 ? 38.337 -6.323 -4.456 1.00 29.99 ? 39 GLN A O 1 ATOM 43 C CB . GLN A 1 7 ? 39.295 -4.224 -2.388 1.00 27.84 ? 39 GLN A CB 1 ATOM 44 C CG . GLN A 1 7 ? 39.900 -3.672 -1.106 1.00 28.57 ? 39 GLN A CG 1 ATOM 45 C CD . GLN A 1 7 ? 40.383 -2.222 -1.209 1.00 28.15 ? 39 GLN A CD 1 ATOM 46 O OE1 . GLN A 1 7 ? 40.611 -1.707 -2.293 1.00 29.13 ? 39 GLN A OE1 1 ATOM 47 N NE2 . GLN A 1 7 ? 40.540 -1.567 -0.070 1.00 27.20 ? 39 GLN A NE2 1 ATOM 48 N N . PHE A 1 8 ? 36.484 -5.644 -3.371 1.00 27.00 ? 40 PHE A N 1 ATOM 49 C CA . PHE A 1 8 ? 35.632 -5.711 -4.555 1.00 23.78 ? 40 PHE A CA 1 ATOM 50 C C . PHE A 1 8 ? 34.530 -4.693 -4.497 1.00 20.63 ? 40 PHE A C 1 ATOM 51 O O . PHE A 1 8 ? 34.115 -4.294 -3.433 1.00 19.12 ? 40 PHE A O 1 ATOM 52 C CB . PHE A 1 8 ? 35.061 -7.103 -4.757 1.00 24.07 ? 40 PHE A CB 1 ATOM 53 C CG . PHE A 1 8 ? 34.155 -7.551 -3.677 1.00 24.91 ? 40 PHE A CG 1 ATOM 54 C CD1 . PHE A 1 8 ? 34.637 -8.324 -2.647 1.00 25.87 ? 40 PHE A CD1 1 ATOM 55 C CD2 . PHE A 1 8 ? 32.803 -7.247 -3.718 1.00 26.28 ? 40 PHE A CD2 1 ATOM 56 C CE1 . PHE A 1 8 ? 33.792 -8.783 -1.648 1.00 27.45 ? 40 PHE A CE1 1 ATOM 57 C CE2 . PHE A 1 8 ? 31.940 -7.697 -2.727 1.00 27.52 ? 40 PHE A CE2 1 ATOM 58 C CZ . PHE A 1 8 ? 32.438 -8.465 -1.681 1.00 28.43 ? 40 PHE A CZ 1 ATOM 59 N N . TRP A 1 9 ? 34.070 -4.285 -5.671 1.00 19.17 ? 41 TRP A N 1 ATOM 60 C CA . TRP A 1 9 ? 33.077 -3.232 -5.786 1.00 17.93 ? 41 TRP A CA 1 ATOM 61 C C . TRP A 1 9 ? 31.735 -3.866 -5.884 1.00 16.64 ? 41 TRP A C 1 ATOM 62 O O . TRP A 1 9 ? 31.634 -5.027 -6.313 1.00 16.14 ? 41 TRP A O 1 ATOM 63 C CB . TRP A 1 9 ? 33.285 -2.430 -7.048 1.00 18.33 ? 41 TRP A CB 1 ATOM 64 C CG . TRP A 1 9 ? 34.479 -1.591 -7.027 1.00 18.35 ? 41 TRP A CG 1 ATOM 65 C CD1 . TRP A 1 9 ? 35.695 -1.875 -7.575 1.00 18.39 ? 41 TRP A CD1 1 ATOM 66 C CD2 . TRP A 1 9 ? 34.582 -0.300 -6.449 1.00 18.14 ? 41 TRP A CD2 1 ATOM 67 N NE1 . TRP A 1 9 ? 36.562 -0.832 -7.352 1.00 18.59 ? 41 TRP A NE1 1 ATOM 68 C CE2 . TRP A 1 9 ? 35.903 0.148 -6.661 1.00 18.21 ? 41 TRP A CE2 1 ATOM 69 C CE3 . TRP A 1 9 ? 33.691 0.519 -5.772 1.00 17.89 ? 41 TRP A CE3 1 ATOM 70 C CZ2 . TRP A 1 9 ? 36.349 1.373 -6.223 1.00 18.40 ? 41 TRP A CZ2 1 ATOM 71 C CZ3 . TRP A 1 9 ? 34.135 1.739 -5.331 1.00 18.49 ? 41 TRP A CZ3 1 ATOM 72 C CH2 . TRP A 1 9 ? 35.452 2.161 -5.559 1.00 18.70 ? 41 TRP A CH2 1 ATOM 73 N N . HIS A 1 10 ? 30.712 -3.103 -5.485 1.00 15.31 ? 42 HIS A N 1 ATOM 74 C CA . HIS A 1 10 ? 29.316 -3.516 -5.668 1.00 14.32 ? 42 HIS A CA 1 ATOM 75 C C . HIS A 1 10 ? 28.575 -2.357 -6.244 1.00 13.60 ? 42 HIS A C 1 ATOM 76 O O . HIS A 1 10 ? 28.465 -1.311 -5.596 1.00 13.50 ? 42 HIS A O 1 ATOM 77 C CB . HIS A 1 10 ? 28.668 -3.910 -4.354 1.00 13.86 ? 42 HIS A CB 1 ATOM 78 C CG . HIS A 1 10 ? 27.258 -4.391 -4.483 1.00 13.60 ? 42 HIS A CG 1 ATOM 79 N ND1 . HIS A 1 10 ? 26.593 -4.994 -3.442 1.00 13.77 ? 42 HIS A ND1 1 ATOM 80 C CD2 . HIS A 1 10 ? 26.385 -4.367 -5.511 1.00 13.73 ? 42 HIS A CD2 1 ATOM 81 C CE1 . HIS A 1 10 ? 25.368 -5.313 -3.817 1.00 13.60 ? 42 HIS A CE1 1 ATOM 82 N NE2 . HIS A 1 10 ? 25.213 -4.937 -5.068 1.00 13.54 ? 42 HIS A NE2 1 ATOM 83 N N . VAL A 1 11 ? 28.075 -2.550 -7.461 1.00 12.77 ? 43 VAL A N 1 ATOM 84 C CA . VAL A 1 11 ? 27.271 -1.545 -8.130 1.00 12.45 ? 43 VAL A CA 1 ATOM 85 C C . VAL A 1 11 ? 25.902 -2.149 -8.391 1.00 12.59 ? 43 VAL A C 1 ATOM 86 O O . VAL A 1 11 ? 25.781 -3.355 -8.689 1.00 12.91 ? 43 VAL A O 1 ATOM 87 C CB . VAL A 1 11 ? 27.880 -1.104 -9.456 1.00 12.33 ? 43 VAL A CB 1 ATOM 88 C CG1 . VAL A 1 11 ? 29.258 -0.505 -9.248 1.00 12.39 ? 43 VAL A CG1 1 ATOM 89 C CG2 . VAL A 1 11 ? 27.951 -2.284 -10.418 1.00 12.63 ? 43 VAL A CG2 1 ATOM 90 N N . THR A 1 12 ? 24.860 -1.328 -8.279 1.00 12.17 ? 44 THR A N 1 ATOM 91 C CA . THR A 1 12 ? 23.542 -1.837 -8.525 1.00 11.81 ? 44 THR A CA 1 ATOM 92 C C . THR A 1 12 ? 22.519 -0.817 -8.992 1.00 11.65 ? 44 THR A C 1 ATOM 93 O O . THR A 1 12 ? 22.699 0.405 -8.832 1.00 11.40 ? 44 THR A O 1 ATOM 94 C CB . THR A 1 12 ? 23.006 -2.523 -7.288 1.00 11.95 ? 44 THR A CB 1 ATOM 95 O OG1 . THR A 1 12 ? 21.861 -3.281 -7.676 1.00 12.78 ? 44 THR A OG1 1 ATOM 96 C CG2 . THR A 1 12 ? 22.617 -1.506 -6.200 1.00 11.96 ? 44 THR A CG2 1 ATOM 97 N N . ASP A 1 13 ? 21.431 -1.364 -9.546 1.00 11.61 ? 45 ASP A N 1 ATOM 98 C CA . ASP A 1 13 ? 20.293 -0.596 -10.061 1.00 11.85 ? 45 ASP A CA 1 ATOM 99 C C . ASP A 1 13 ? 20.773 0.672 -10.794 1.00 12.30 ? 45 ASP A C 1 ATOM 100 O O . ASP A 1 13 ? 20.573 1.817 -10.353 1.00 11.89 ? 45 ASP A O 1 ATOM 101 C CB . ASP A 1 13 ? 19.270 -0.314 -8.944 1.00 11.60 ? 45 ASP A CB 1 ATOM 102 C CG . ASP A 1 13 ? 18.846 -1.597 -8.186 1.00 11.39 ? 45 ASP A CG 1 ATOM 103 O OD1 . ASP A 1 13 ? 19.494 -1.964 -7.175 1.00 11.04 ? 45 ASP A OD1 1 ATOM 104 O OD2 . ASP A 1 13 ? 17.843 -2.228 -8.578 1.00 11.14 -1 45 ASP A OD2 1 ATOM 105 N N . LEU A 1 14 ? 21.427 0.422 -11.931 1.00 13.06 ? 46 LEU A N 1 ATOM 106 C CA . LEU A 1 14 ? 21.967 1.491 -12.764 1.00 13.48 ? 46 LEU A CA 1 ATOM 107 C C . LEU A 1 14 ? 20.811 2.265 -13.379 1.00 13.60 ? 46 LEU A C 1 ATOM 108 O O . LEU A 1 14 ? 20.827 3.487 -13.351 1.00 14.18 ? 46 LEU A O 1 ATOM 109 C CB . LEU A 1 14 ? 22.925 0.923 -13.820 1.00 13.96 ? 46 LEU A CB 1 ATOM 110 C CG . LEU A 1 14 ? 24.193 0.188 -13.298 1.00 14.47 ? 46 LEU A CG 1 ATOM 111 C CD1 . LEU A 1 14 ? 25.001 -0.544 -14.355 1.00 14.54 ? 46 LEU A CD1 1 ATOM 112 C CD2 . LEU A 1 14 ? 25.113 1.182 -12.612 1.00 14.57 ? 46 LEU A CD2 1 ATOM 113 N N . HIS A 1 15 ? 19.780 1.560 -13.853 1.00 13.57 ? 47 HIS A N 1 ATOM 114 C CA . HIS A 1 15 ? 18.563 2.190 -14.365 1.00 13.98 ? 47 HIS A CA 1 ATOM 115 C C . HIS A 1 15 ? 18.906 3.398 -15.266 1.00 14.93 ? 47 HIS A C 1 ATOM 116 O O . HIS A 1 15 ? 18.693 4.587 -14.897 1.00 13.54 ? 47 HIS A O 1 ATOM 117 C CB . HIS A 1 15 ? 17.620 2.603 -13.220 1.00 14.01 ? 47 HIS A CB 1 ATOM 118 C CG . HIS A 1 15 ? 16.962 1.450 -12.505 1.00 13.93 ? 47 HIS A CG 1 ATOM 119 N ND1 . HIS A 1 15 ? 16.196 0.511 -13.157 1.00 13.89 ? 47 HIS A ND1 1 ATOM 120 C CD2 . HIS A 1 15 ? 16.934 1.101 -11.195 1.00 13.75 ? 47 HIS A CD2 1 ATOM 121 C CE1 . HIS A 1 15 ? 15.740 -0.373 -12.290 1.00 13.46 ? 47 HIS A CE1 1 ATOM 122 N NE2 . HIS A 1 15 ? 16.173 -0.036 -11.093 1.00 13.36 ? 47 HIS A NE2 1 ATOM 123 N N . LEU A 1 16 ? 19.471 3.059 -16.435 1.00 16.20 ? 48 LEU A N 1 ATOM 124 C CA . LEU A 1 16 ? 19.807 4.037 -17.478 1.00 17.04 ? 48 LEU A CA 1 ATOM 125 C C . LEU A 1 16 ? 18.562 4.500 -18.197 1.00 17.32 ? 48 LEU A C 1 ATOM 126 O O . LEU A 1 16 ? 17.745 3.668 -18.601 1.00 17.06 ? 48 LEU A O 1 ATOM 127 C CB . LEU A 1 16 ? 20.737 3.435 -18.549 1.00 17.23 ? 48 LEU A CB 1 ATOM 128 C CG . LEU A 1 16 ? 20.951 4.321 -19.808 1.00 17.13 ? 48 LEU A CG 1 ATOM 129 C CD1 . LEU A 1 16 ? 21.858 5.510 -19.550 1.00 17.25 ? 48 LEU A CD1 1 ATOM 130 C CD2 . LEU A 1 16 ? 21.536 3.522 -20.945 1.00 17.41 ? 48 LEU A CD2 1 ATOM 131 N N . ASP A 1 17 ? 18.444 5.792 -18.420 1.00 17.78 ? 49 ASP A N 1 ATOM 132 C CA . ASP A 1 17 ? 17.361 6.372 -19.155 1.00 19.92 ? 49 ASP A CA 1 ATOM 133 C C . ASP A 1 17 ? 18.040 6.947 -20.345 1.00 19.70 ? 49 ASP A C 1 ATOM 134 O O . ASP A 1 17 ? 18.640 7.973 -20.260 1.00 18.18 ? 49 ASP A O 1 ATOM 135 C CB . ASP A 1 17 ? 16.722 7.486 -18.375 1.00 21.95 ? 49 ASP A CB 1 ATOM 136 C CG . ASP A 1 17 ? 15.378 7.884 -18.895 1.00 23.18 ? 49 ASP A CG 1 ATOM 137 O OD1 . ASP A 1 17 ? 15.028 7.604 -20.020 1.00 22.78 ? 49 ASP A OD1 1 ATOM 138 O OD2 . ASP A 1 17 ? 14.669 8.546 -18.177 1.00 24.09 -1 49 ASP A OD2 1 ATOM 139 N N . PRO A 1 18 ? 17.938 6.215 -21.514 1.00 20.36 ? 50 PRO A N 1 ATOM 140 C CA . PRO A 1 18 ? 18.632 6.764 -22.670 1.00 20.11 ? 50 PRO A CA 1 ATOM 141 C C . PRO A 1 18 ? 18.058 8.017 -23.264 1.00 20.40 ? 50 PRO A C 1 ATOM 142 O O . PRO A 1 18 ? 18.635 8.574 -24.142 1.00 21.81 ? 50 PRO A O 1 ATOM 143 C CB . PRO A 1 18 ? 18.495 5.659 -23.687 1.00 19.88 ? 50 PRO A CB 1 ATOM 144 C CG . PRO A 1 18 ? 18.298 4.444 -22.922 1.00 19.90 ? 50 PRO A CG 1 ATOM 145 C CD . PRO A 1 18 ? 17.315 4.915 -21.986 1.00 20.21 ? 50 PRO A CD 1 ATOM 146 N N . THR A 1 19 ? 16.935 8.442 -22.731 1.00 19.88 ? 51 THR A N 1 ATOM 147 C CA . THR A 1 19 ? 16.199 9.598 -23.157 1.00 19.47 ? 51 THR A CA 1 ATOM 148 C C . THR A 1 19 ? 16.645 10.887 -22.586 1.00 19.88 ? 51 THR A C 1 ATOM 149 O O . THR A 1 19 ? 16.394 11.921 -23.121 1.00 19.74 ? 51 THR A O 1 ATOM 150 C CB . THR A 1 19 ? 14.803 9.443 -22.616 1.00 19.69 ? 51 THR A CB 1 ATOM 151 O OG1 . THR A 1 19 ? 14.290 8.224 -23.088 1.00 19.17 ? 51 THR A OG1 1 ATOM 152 C CG2 . THR A 1 19 ? 13.901 10.494 -23.097 1.00 21.25 ? 51 THR A CG2 1 ATOM 153 N N . TYR A 1 20 ? 17.252 10.811 -21.445 1.00 21.19 ? 52 TYR A N 1 ATOM 154 C CA . TYR A 1 20 ? 17.619 11.956 -20.728 1.00 21.43 ? 52 TYR A CA 1 ATOM 155 C C . TYR A 1 20 ? 18.313 12.949 -21.547 1.00 22.51 ? 52 TYR A C 1 ATOM 156 O O . TYR A 1 20 ? 19.032 12.628 -22.432 1.00 21.16 ? 52 TYR A O 1 ATOM 157 C CB . TYR A 1 20 ? 18.449 11.549 -19.553 1.00 21.14 ? 52 TYR A CB 1 ATOM 158 C CG . TYR A 1 20 ? 18.505 12.600 -18.537 1.00 20.50 ? 52 TYR A CG 1 ATOM 159 C CD1 . TYR A 1 20 ? 19.382 13.606 -18.642 1.00 20.34 ? 52 TYR A CD1 1 ATOM 160 C CD2 . TYR A 1 20 ? 17.679 12.590 -17.481 1.00 20.57 ? 52 TYR A CD2 1 ATOM 161 C CE1 . TYR A 1 20 ? 19.429 14.575 -17.715 1.00 20.45 ? 52 TYR A CE1 1 ATOM 162 C CE2 . TYR A 1 20 ? 17.721 13.576 -16.565 1.00 20.54 ? 52 TYR A CE2 1 ATOM 163 C CZ . TYR A 1 20 ? 18.602 14.550 -16.708 1.00 20.60 ? 52 TYR A CZ 1 ATOM 164 O OH . TYR A 1 20 ? 18.658 15.512 -15.798 1.00 21.42 ? 52 TYR A OH 1 ATOM 165 N N . HIS A 1 21 ? 18.047 14.187 -21.222 1.00 25.85 ? 53 HIS A N 1 ATOM 166 C CA . HIS A 1 21 ? 18.691 15.307 -21.802 1.00 30.90 ? 53 HIS A CA 1 ATOM 167 C C . HIS A 1 21 ? 18.036 16.450 -21.166 1.00 29.95 ? 53 HIS A C 1 ATOM 168 O O . HIS A 1 21 ? 16.939 16.371 -20.799 1.00 29.72 ? 53 HIS A O 1 ATOM 169 C CB . HIS A 1 21 ? 18.822 15.180 -23.292 1.00 37.09 ? 53 HIS A CB 1 ATOM 170 C CG . HIS A 1 21 ? 17.589 15.530 -24.045 1.00 44.26 ? 53 HIS A CG 1 ATOM 171 N ND1 . HIS A 1 21 ? 16.341 15.194 -23.600 1.00 48.45 ? 53 HIS A ND1 1 ATOM 172 C CD2 . HIS A 1 21 ? 17.413 16.193 -25.201 1.00 49.01 ? 53 HIS A CD2 1 ATOM 173 C CE1 . HIS A 1 21 ? 15.446 15.603 -24.471 1.00 51.37 ? 53 HIS A CE1 1 ATOM 174 N NE2 . HIS A 1 21 ? 16.072 16.230 -25.441 1.00 54.12 ? 53 HIS A NE2 1 ATOM 175 N N . ILE A 1 22 ? 18.777 17.519 -21.063 1.00 30.87 ? 54 ILE A N 1 ATOM 176 C CA . ILE A 1 22 ? 18.365 18.861 -20.661 1.00 31.34 ? 54 ILE A CA 1 ATOM 177 C C . ILE A 1 22 ? 17.646 19.595 -21.793 1.00 32.88 ? 54 ILE A C 1 ATOM 178 O O . ILE A 1 22 ? 18.162 19.731 -22.902 1.00 31.96 ? 54 ILE A O 1 ATOM 179 C CB . ILE A 1 22 ? 19.586 19.701 -20.227 1.00 30.82 ? 54 ILE A CB 1 ATOM 180 C CG1 . ILE A 1 22 ? 20.322 18.996 -19.085 1.00 30.86 ? 54 ILE A CG1 1 ATOM 181 C CG2 . ILE A 1 22 ? 19.176 21.118 -19.840 1.00 30.78 ? 54 ILE A CG2 1 ATOM 182 C CD1 . ILE A 1 22 ? 19.419 18.563 -17.953 1.00 31.17 ? 54 ILE A CD1 1 ATOM 183 N N . THR A 1 23 ? 16.446 20.066 -21.495 1.00 35.42 ? 55 THR A N 1 ATOM 184 C CA . THR A 1 23 ? 15.680 20.885 -22.429 1.00 38.25 ? 55 THR A CA 1 ATOM 185 C C . THR A 1 23 ? 14.761 21.779 -21.584 1.00 38.84 ? 55 THR A C 1 ATOM 186 O O . THR A 1 23 ? 14.589 21.538 -20.382 1.00 40.07 ? 55 THR A O 1 ATOM 187 C CB . THR A 1 23 ? 14.929 19.998 -23.464 1.00 39.52 ? 55 THR A CB 1 ATOM 188 O OG1 . THR A 1 23 ? 14.572 20.768 -24.617 1.00 40.05 ? 55 THR A OG1 1 ATOM 189 C CG2 . THR A 1 23 ? 13.675 19.361 -22.862 1.00 40.69 ? 55 THR A CG2 1 ATOM 190 N N . ASP A 1 24 ? 14.198 22.821 -22.181 1.00 39.50 ? 56 ASP A N 1 ATOM 191 C CA . ASP A 1 24 ? 13.448 23.812 -21.392 1.00 40.60 ? 56 ASP A CA 1 ATOM 192 C C . ASP A 1 24 ? 12.064 23.350 -20.919 1.00 37.91 ? 56 ASP A C 1 ATOM 193 O O . ASP A 1 24 ? 11.568 23.857 -19.927 1.00 39.65 ? 56 ASP A O 1 ATOM 194 C CB . ASP A 1 24 ? 13.354 25.136 -22.151 1.00 42.10 ? 56 ASP A CB 1 ATOM 195 C CG . ASP A 1 24 ? 14.713 25.762 -22.360 1.00 43.58 ? 56 ASP A CG 1 ATOM 196 O OD1 . ASP A 1 24 ? 15.406 26.042 -21.350 1.00 40.81 ? 56 ASP A OD1 1 ATOM 197 O OD2 . ASP A 1 24 ? 15.095 25.933 -23.540 1.00 45.67 -1 56 ASP A OD2 1 ATOM 198 N N . ASP A 1 25 ? 11.457 22.401 -21.626 1.00 35.18 ? 57 ASP A N 1 ATOM 199 C CA . ASP A 1 25 ? 10.219 21.745 -21.193 1.00 33.62 ? 57 ASP A CA 1 ATOM 200 C C . ASP A 1 25 ? 10.602 20.560 -20.304 1.00 32.41 ? 57 ASP A C 1 ATOM 201 O O . ASP A 1 25 ? 11.011 19.484 -20.782 1.00 30.83 ? 57 ASP A O 1 ATOM 202 C CB . ASP A 1 25 ? 9.426 21.266 -22.420 1.00 35.35 ? 57 ASP A CB 1 ATOM 203 C CG . ASP A 1 25 ? 8.045 20.710 -22.081 1.00 35.80 ? 57 ASP A CG 1 ATOM 204 O OD1 . ASP A 1 25 ? 7.708 20.537 -20.896 1.00 34.54 ? 57 ASP A OD1 1 ATOM 205 O OD2 . ASP A 1 25 ? 7.276 20.452 -23.034 1.00 39.28 -1 57 ASP A OD2 1 ATOM 206 N N . HIS A 1 26 ? 10.454 20.763 -19.000 1.00 31.47 ? 58 HIS A N 1 ATOM 207 C CA . HIS A 1 26 ? 10.863 19.769 -18.010 1.00 30.72 ? 58 HIS A CA 1 ATOM 208 C C . HIS A 1 26 ? 10.009 18.488 -18.007 1.00 28.95 ? 58 HIS A C 1 ATOM 209 O O . HIS A 1 26 ? 10.401 17.487 -17.412 1.00 31.15 ? 58 HIS A O 1 ATOM 210 C CB . HIS A 1 26 ? 10.933 20.406 -16.603 1.00 31.04 ? 58 HIS A CB 1 ATOM 211 C CG . HIS A 1 26 ? 12.117 21.310 -16.395 1.00 30.85 ? 58 HIS A CG 1 ATOM 212 N ND1 . HIS A 1 26 ? 13.125 21.467 -17.332 1.00 30.46 ? 58 HIS A ND1 1 ATOM 213 C CD2 . HIS A 1 26 ? 12.472 22.068 -15.328 1.00 29.68 ? 58 HIS A CD2 1 ATOM 214 C CE1 . HIS A 1 26 ? 14.034 22.298 -16.860 1.00 30.23 ? 58 HIS A CE1 1 ATOM 215 N NE2 . HIS A 1 26 ? 13.666 22.669 -15.644 1.00 30.74 ? 58 HIS A NE2 1 ATOM 216 N N . THR A 1 27 ? 8.876 18.490 -18.688 1.00 26.84 ? 59 THR A N 1 ATOM 217 C CA . THR A 1 27 ? 8.130 17.260 -18.857 1.00 27.23 ? 59 THR A CA 1 ATOM 218 C C . THR A 1 27 ? 8.802 16.353 -19.880 1.00 29.23 ? 59 THR A C 1 ATOM 219 O O . THR A 1 27 ? 8.507 15.161 -19.923 1.00 30.05 ? 59 THR A O 1 ATOM 220 C CB . THR A 1 27 ? 6.721 17.511 -19.351 1.00 26.05 ? 59 THR A CB 1 ATOM 221 O OG1 . THR A 1 27 ? 6.791 17.906 -20.721 1.00 25.96 ? 59 THR A OG1 1 ATOM 222 C CG2 . THR A 1 27 ? 6.014 18.587 -18.490 1.00 25.93 ? 59 THR A CG2 1 ATOM 223 N N . LYS A 1 28 ? 9.708 16.911 -20.684 1.00 31.69 ? 60 LYS A N 1 ATOM 224 C CA . LYS A 1 28 ? 10.328 16.186 -21.796 1.00 33.81 ? 60 LYS A CA 1 ATOM 225 C C . LYS A 1 28 ? 11.762 15.736 -21.534 1.00 32.45 ? 60 LYS A C 1 ATOM 226 O O . LYS A 1 28 ? 12.323 14.924 -22.307 1.00 34.87 ? 60 LYS A O 1 ATOM 227 C CB . LYS A 1 28 ? 10.289 17.046 -23.075 1.00 37.29 ? 60 LYS A CB 1 ATOM 228 C CG . LYS A 1 28 ? 8.899 17.299 -23.658 1.00 38.67 ? 60 LYS A CG 1 ATOM 229 C CD . LYS A 1 28 ? 8.179 15.993 -23.963 1.00 41.05 ? 60 LYS A CD 1 ATOM 230 C CE . LYS A 1 28 ? 6.749 16.234 -24.387 1.00 42.24 ? 60 LYS A CE 1 ATOM 231 N NZ . LYS A 1 28 ? 6.724 16.922 -25.705 1.00 42.35 1 60 LYS A NZ 1 ATOM 232 N N . VAL A 1 29 ? 12.345 16.241 -20.449 1.00 29.06 ? 61 VAL A N 1 ATOM 233 C CA . VAL A 1 29 ? 13.725 15.891 -20.061 1.00 26.48 ? 61 VAL A CA 1 ATOM 234 C C . VAL A 1 29 ? 14.012 14.371 -20.034 1.00 25.20 ? 61 VAL A C 1 ATOM 235 O O . VAL A 1 29 ? 15.068 13.910 -20.495 1.00 25.09 ? 61 VAL A O 1 ATOM 236 C CB . VAL A 1 29 ? 14.064 16.507 -18.697 1.00 25.17 ? 61 VAL A CB 1 ATOM 237 C CG1 . VAL A 1 29 ? 15.256 15.818 -18.052 1.00 25.32 ? 61 VAL A CG1 1 ATOM 238 C CG2 . VAL A 1 29 ? 14.310 17.986 -18.854 1.00 24.90 ? 61 VAL A CG2 1 ATOM 239 N N . CYS A 1 30 ? 13.088 13.588 -19.505 1.00 23.23 ? 62 CYS A N 1 ATOM 240 C CA . CYS A 1 30 ? 13.338 12.166 -19.428 1.00 22.55 ? 62 CYS A CA 1 ATOM 241 C C . CYS A 1 30 ? 12.046 11.406 -19.361 1.00 20.70 ? 62 CYS A C 1 ATOM 242 O O . CYS A 1 30 ? 11.131 11.770 -18.616 1.00 20.58 ? 62 CYS A O 1 ATOM 243 C CB . CYS A 1 30 ? 14.178 11.842 -18.190 1.00 23.57 ? 62 CYS A CB 1 ATOM 244 S SG . CYS A 1 30 ? 13.199 11.757 -16.671 1.00 24.48 ? 62 CYS A SG 1 ATOM 245 N N . ALA A 1 31 ? 11.999 10.318 -20.107 1.00 18.72 ? 63 ALA A N 1 ATOM 246 C CA . ALA A 1 31 ? 10.793 9.542 -20.196 1.00 18.51 ? 63 ALA A CA 1 ATOM 247 C C . ALA A 1 31 ? 10.418 8.892 -18.845 1.00 18.35 ? 63 ALA A C 1 ATOM 248 O O . ALA A 1 31 ? 9.230 8.679 -18.563 1.00 18.69 ? 63 ALA A O 1 ATOM 249 C CB . ALA A 1 31 ? 10.941 8.487 -21.269 1.00 18.23 ? 63 ALA A CB 1 ATOM 250 N N . SER A 1 32 ? 11.409 8.587 -18.009 1.00 17.64 ? 64 SER A N 1 ATOM 251 C CA . SER A 1 32 ? 11.141 7.938 -16.720 1.00 17.15 ? 64 SER A CA 1 ATOM 252 C C . SER A 1 32 ? 10.267 8.802 -15.823 1.00 15.85 ? 64 SER A C 1 ATOM 253 O O . SER A 1 32 ? 9.462 8.263 -15.081 1.00 15.38 ? 64 SER A O 1 ATOM 254 C CB . SER A 1 32 ? 12.432 7.570 -15.998 1.00 17.84 ? 64 SER A CB 1 ATOM 255 O OG . SER A 1 32 ? 13.349 8.661 -16.022 1.00 18.84 ? 64 SER A OG 1 ATOM 256 N N . SER A 1 33 ? 10.388 10.130 -15.930 1.00 14.66 ? 65 SER A N 1 ATOM 257 C CA . SER A 1 33 ? 9.552 11.027 -15.139 1.00 13.71 ? 65 SER A CA 1 ATOM 258 C C . SER A 1 33 ? 8.076 10.879 -15.539 1.00 13.41 ? 65 SER A C 1 ATOM 259 O O . SER A 1 33 ? 7.186 11.375 -14.851 1.00 13.09 ? 65 SER A O 1 ATOM 260 C CB . SER A 1 33 ? 9.991 12.467 -15.288 1.00 13.32 ? 65 SER A CB 1 ATOM 261 O OG . SER A 1 33 ? 9.031 13.171 -16.046 1.00 13.90 ? 65 SER A OG 1 ATOM 262 N N . LYS A 1 34 ? 7.831 10.216 -16.662 1.00 13.11 ? 66 LYS A N 1 ATOM 263 C CA . LYS A 1 34 ? 6.492 9.917 -17.116 1.00 13.68 ? 66 LYS A CA 1 ATOM 264 C C . LYS A 1 34 ? 5.591 11.155 -17.255 1.00 14.01 ? 66 LYS A C 1 ATOM 265 O O . LYS A 1 34 ? 4.388 11.120 -17.033 1.00 13.67 ? 66 LYS A O 1 ATOM 266 C CB . LYS A 1 34 ? 5.848 8.865 -16.223 1.00 13.89 ? 66 LYS A CB 1 ATOM 267 C CG . LYS A 1 34 ? 6.602 7.544 -16.200 1.00 14.19 ? 66 LYS A CG 1 ATOM 268 C CD . LYS A 1 34 ? 6.322 6.813 -14.894 1.00 14.41 ? 66 LYS A CD 1 ATOM 269 C CE . LYS A 1 34 ? 7.316 5.701 -14.628 1.00 14.68 ? 66 LYS A CE 1 ATOM 270 N NZ . LYS A 1 34 ? 8.267 6.024 -13.529 1.00 14.95 1 66 LYS A NZ 1 ATOM 271 N N . GLY A 1 35 ? 6.166 12.257 -17.669 1.00 14.56 ? 67 GLY A N 1 ATOM 272 C CA . GLY A 1 35 ? 5.323 13.353 -17.998 1.00 15.75 ? 67 GLY A CA 1 ATOM 273 C C . GLY A 1 35 ? 5.343 14.420 -16.953 1.00 17.06 ? 67 GLY A C 1 ATOM 274 O O . GLY A 1 35 ? 4.939 15.565 -17.229 1.00 17.69 ? 67 GLY A O 1 ATOM 275 N N . ALA A 1 36 ? 5.824 14.081 -15.760 1.00 18.17 ? 68 ALA A N 1 ATOM 276 C CA . ALA A 1 36 ? 5.955 15.099 -14.705 1.00 18.59 ? 68 ALA A CA 1 ATOM 277 C C . ALA A 1 36 ? 7.126 16.020 -15.003 1.00 17.96 ? 68 ALA A C 1 ATOM 278 O O . ALA A 1 36 ? 8.056 15.634 -15.692 1.00 17.00 ? 68 ALA A O 1 ATOM 279 C CB . ALA A 1 36 ? 6.121 14.453 -13.342 1.00 18.90 ? 68 ALA A CB 1 ATOM 280 N N . ASN A 1 37 ? 7.040 17.248 -14.508 1.00 18.45 ? 69 ASN A N 1 ATOM 281 C CA . ASN A 1 37 ? 8.145 18.183 -14.608 1.00 19.44 ? 69 ASN A CA 1 ATOM 282 C C . ASN A 1 37 ? 9.258 17.640 -13.761 1.00 19.51 ? 69 ASN A C 1 ATOM 283 O O . ASN A 1 37 ? 9.065 17.354 -12.577 1.00 19.17 ? 69 ASN A O 1 ATOM 284 C CB . ASN A 1 37 ? 7.760 19.604 -14.145 1.00 20.12 ? 69 ASN A CB 1 ATOM 285 C CG . ASN A 1 37 ? 7.303 20.501 -15.290 1.00 20.95 ? 69 ASN A CG 1 ATOM 286 O OD1 . ASN A 1 37 ? 7.750 20.339 -16.415 1.00 22.11 ? 69 ASN A OD1 1 ATOM 287 N ND2 . ASN A 1 37 ? 6.433 21.468 -14.998 1.00 22.25 ? 69 ASN A ND2 1 ATOM 288 N N . ALA A 1 38 ? 10.409 17.456 -14.390 1.00 20.23 ? 70 ALA A N 1 ATOM 289 C CA . ALA A 1 38 ? 11.602 17.032 -13.685 1.00 21.53 ? 70 ALA A CA 1 ATOM 290 C C . ALA A 1 38 ? 11.910 18.137 -12.695 1.00 22.56 ? 70 ALA A C 1 ATOM 291 O O . ALA A 1 38 ? 11.844 19.314 -13.050 1.00 23.76 ? 70 ALA A O 1 ATOM 292 C CB . ALA A 1 38 ? 12.758 16.822 -14.644 1.00 21.35 ? 70 ALA A CB 1 ATOM 293 N N . SER A 1 39 ? 12.193 17.769 -11.451 1.00 22.79 ? 71 SER A N 1 ATOM 294 C CA . SER A 1 39 ? 12.193 18.753 -10.392 1.00 23.13 ? 71 SER A CA 1 ATOM 295 C C . SER A 1 39 ? 13.170 19.871 -10.649 1.00 22.78 ? 71 SER A C 1 ATOM 296 O O . SER A 1 39 ? 12.810 21.036 -10.568 1.00 22.30 ? 71 SER A O 1 ATOM 297 C CB . SER A 1 39 ? 12.529 18.141 -9.044 1.00 23.43 ? 71 SER A CB 1 ATOM 298 O OG . SER A 1 39 ? 12.423 19.176 -8.088 1.00 23.16 ? 71 SER A OG 1 ATOM 299 N N . ASN A 1 40 ? 14.418 19.505 -10.914 1.00 22.96 ? 72 ASN A N 1 ATOM 300 C CA . ASN A 1 40 ? 15.468 20.485 -11.108 1.00 22.77 ? 72 ASN A CA 1 ATOM 301 C C . ASN A 1 40 ? 16.669 19.878 -11.802 1.00 21.01 ? 72 ASN A C 1 ATOM 302 O O . ASN A 1 40 ? 17.694 19.657 -11.186 1.00 19.92 ? 72 ASN A O 1 ATOM 303 C CB . ASN A 1 40 ? 15.904 21.065 -9.791 1.00 23.97 ? 72 ASN A CB 1 ATOM 304 C CG . ASN A 1 40 ? 17.084 21.963 -9.960 1.00 26.72 ? 72 ASN A CG 1 ATOM 305 O OD1 . ASN A 1 40 ? 17.293 22.541 -11.038 1.00 28.47 ? 72 ASN A OD1 1 ATOM 306 N ND2 . ASN A 1 40 ? 17.895 22.066 -8.926 1.00 29.54 ? 72 ASN A ND2 1 ATOM 307 N N . PRO A 1 41 ? 16.543 19.649 -13.108 1.00 19.73 ? 73 PRO A N 1 ATOM 308 C CA . PRO A 1 41 ? 17.393 18.684 -13.749 1.00 19.40 ? 73 PRO A CA 1 ATOM 309 C C . PRO A 1 41 ? 18.753 19.236 -14.049 1.00 18.73 ? 73 PRO A C 1 ATOM 310 O O . PRO A 1 41 ? 18.879 20.413 -14.271 1.00 18.90 ? 73 PRO A O 1 ATOM 311 C CB . PRO A 1 41 ? 16.638 18.372 -15.052 1.00 19.11 ? 73 PRO A CB 1 ATOM 312 C CG . PRO A 1 41 ? 15.808 19.569 -15.326 1.00 18.69 ? 73 PRO A CG 1 ATOM 313 C CD . PRO A 1 41 ? 15.693 20.370 -14.069 1.00 18.91 ? 73 PRO A CD 1 ATOM 314 N N . GLY A 1 42 ? 19.749 18.366 -14.064 1.00 18.55 ? 74 GLY A N 1 ATOM 315 C CA . GLY A 1 42 ? 21.088 18.733 -14.457 1.00 18.89 ? 74 GLY A CA 1 ATOM 316 C C . GLY A 1 42 ? 21.764 17.648 -15.281 1.00 19.36 ? 74 GLY A C 1 ATOM 317 O O . GLY A 1 42 ? 21.142 16.631 -15.640 1.00 17.93 ? 74 GLY A O 1 ATOM 318 N N . PRO A 1 43 ? 23.053 17.862 -15.594 1.00 20.51 ? 75 PRO A N 1 ATOM 319 C CA . PRO A 1 43 ? 23.820 16.931 -16.428 1.00 21.49 ? 75 PRO A CA 1 ATOM 320 C C . PRO A 1 43 ? 23.996 15.546 -15.805 1.00 23.36 ? 75 PRO A C 1 ATOM 321 O O . PRO A 1 43 ? 24.203 14.571 -16.541 1.00 24.46 ? 75 PRO A O 1 ATOM 322 C CB . PRO A 1 43 ? 25.178 17.616 -16.588 1.00 21.12 ? 75 PRO A CB 1 ATOM 323 C CG . PRO A 1 43 ? 25.237 18.679 -15.544 1.00 21.07 ? 75 PRO A CG 1 ATOM 324 C CD . PRO A 1 43 ? 23.831 19.054 -15.209 1.00 20.55 ? 75 PRO A CD 1 ATOM 325 N N . PHE A 1 44 ? 23.921 15.450 -14.472 1.00 24.83 ? 76 PHE A N 1 ATOM 326 C CA . PHE A 1 44 ? 24.028 14.141 -13.793 1.00 24.84 ? 76 PHE A CA 1 ATOM 327 C C . PHE A 1 44 ? 22.717 13.573 -13.278 1.00 23.17 ? 76 PHE A C 1 ATOM 328 O O . PHE A 1 44 ? 22.719 12.482 -12.690 1.00 22.35 ? 76 PHE A O 1 ATOM 329 C CB . PHE A 1 44 ? 25.024 14.233 -12.671 1.00 25.63 ? 76 PHE A CB 1 ATOM 330 C CG . PHE A 1 44 ? 26.298 14.841 -13.100 1.00 27.19 ? 76 PHE A CG 1 ATOM 331 C CD1 . PHE A 1 44 ? 27.146 14.140 -13.921 1.00 28.27 ? 76 PHE A CD1 1 ATOM 332 C CD2 . PHE A 1 44 ? 26.627 16.134 -12.735 1.00 29.04 ? 76 PHE A CD2 1 ATOM 333 C CE1 . PHE A 1 44 ? 28.333 14.700 -14.346 1.00 29.24 ? 76 PHE A CE1 1 ATOM 334 C CE2 . PHE A 1 44 ? 27.818 16.700 -13.156 1.00 29.59 ? 76 PHE A CE2 1 ATOM 335 C CZ . PHE A 1 44 ? 28.675 15.981 -13.957 1.00 29.03 ? 76 PHE A CZ 1 ATOM 336 N N . GLY A 1 45 ? 21.628 14.318 -13.483 1.00 21.24 ? 77 GLY A N 1 ATOM 337 C CA . GLY A 1 45 ? 20.294 13.766 -13.406 1.00 20.28 ? 77 GLY A CA 1 ATOM 338 C C . GLY A 1 45 ? 19.308 14.574 -12.598 1.00 19.65 ? 77 GLY A C 1 ATOM 339 O O . GLY A 1 45 ? 19.542 15.723 -12.282 1.00 19.38 ? 77 GLY A O 1 ATOM 340 N N . ASP A 1 46 ? 18.194 13.941 -12.267 1.00 19.50 ? 78 ASP A N 1 ATOM 341 C CA . ASP A 1 46 ? 17.139 14.572 -11.504 1.00 20.00 ? 78 ASP A CA 1 ATOM 342 C C . ASP A 1 46 ? 16.427 13.544 -10.642 1.00 19.72 ? 78 ASP A C 1 ATOM 343 O O . ASP A 1 46 ? 16.296 12.386 -11.026 1.00 20.08 ? 78 ASP A O 1 ATOM 344 C CB . ASP A 1 46 ? 16.136 15.197 -12.440 1.00 20.41 ? 78 ASP A CB 1 ATOM 345 C CG . ASP A 1 46 ? 15.144 16.020 -11.714 1.00 21.25 ? 78 ASP A CG 1 ATOM 346 O OD1 . ASP A 1 46 ? 15.561 16.965 -11.006 1.00 21.50 ? 78 ASP A OD1 1 ATOM 347 O OD2 . ASP A 1 46 ? 13.952 15.698 -11.827 1.00 22.26 -1 78 ASP A OD2 1 ATOM 348 N N . VAL A 1 47 ? 15.954 13.953 -9.474 1.00 19.17 ? 79 VAL A N 1 ATOM 349 C CA . VAL A 1 47 ? 15.358 12.976 -8.547 1.00 18.90 ? 79 VAL A CA 1 ATOM 350 C C . VAL A 1 47 ? 14.157 12.233 -9.148 1.00 18.47 ? 79 VAL A C 1 ATOM 351 O O . VAL A 1 47 ? 13.837 11.132 -8.723 1.00 17.84 ? 79 VAL A O 1 ATOM 352 C CB . VAL A 1 47 ? 14.944 13.604 -7.188 1.00 18.83 ? 79 VAL A CB 1 ATOM 353 C CG1 . VAL A 1 47 ? 16.144 13.746 -6.279 1.00 18.96 ? 79 VAL A CG1 1 ATOM 354 C CG2 . VAL A 1 47 ? 14.261 14.953 -7.363 1.00 19.32 ? 79 VAL A CG2 1 ATOM 355 N N . LEU A 1 48 ? 13.515 12.847 -10.136 1.00 18.55 ? 80 LEU A N 1 ATOM 356 C CA . LEU A 1 48 ? 12.315 12.305 -10.768 1.00 18.92 ? 80 LEU A CA 1 ATOM 357 C C . LEU A 1 48 ? 12.643 11.494 -12.034 1.00 19.16 ? 80 LEU A C 1 ATOM 358 O O . LEU A 1 48 ? 11.772 10.891 -12.648 1.00 18.34 ? 80 LEU A O 1 ATOM 359 C CB . LEU A 1 48 ? 11.392 13.474 -11.111 1.00 18.80 ? 80 LEU A CB 1 ATOM 360 C CG . LEU A 1 48 ? 10.158 13.793 -10.258 1.00 18.48 ? 80 LEU A CG 1 ATOM 361 C CD1 . LEU A 1 48 ? 10.208 13.153 -8.905 1.00 18.62 ? 80 LEU A CD1 1 ATOM 362 C CD2 . LEU A 1 48 ? 9.979 15.295 -10.136 1.00 18.58 ? 80 LEU A CD2 1 ATOM 363 N N . CYS A 1 49 ? 13.920 11.478 -12.387 1.00 19.87 ? 81 CYS A N 1 ATOM 364 C CA . CYS A 1 49 ? 14.407 10.863 -13.599 1.00 20.22 ? 81 CYS A CA 1 ATOM 365 C C . CYS A 1 49 ? 15.380 9.770 -13.244 1.00 20.17 ? 81 CYS A C 1 ATOM 366 O O . CYS A 1 49 ? 16.194 9.928 -12.340 1.00 21.01 ? 81 CYS A O 1 ATOM 367 C CB . CYS A 1 49 ? 15.166 11.897 -14.427 1.00 20.98 ? 81 CYS A CB 1 ATOM 368 S SG . CYS A 1 49 ? 14.118 13.041 -15.341 1.00 22.73 ? 81 CYS A SG 1 ATOM 369 N N . ASP A 1 50 ? 15.305 8.661 -13.960 1.00 19.34 ? 82 ASP A N 1 ATOM 370 C CA . ASP A 1 50 ? 16.353 7.683 -13.927 1.00 18.66 ? 82 ASP A CA 1 ATOM 371 C C . ASP A 1 50 ? 17.711 8.209 -14.434 1.00 18.38 ? 82 ASP A C 1 ATOM 372 O O . ASP A 1 50 ? 17.847 9.371 -14.798 1.00 17.27 ? 82 ASP A O 1 ATOM 373 C CB . ASP A 1 50 ? 15.908 6.504 -14.744 1.00 19.43 ? 82 ASP A CB 1 ATOM 374 C CG . ASP A 1 50 ? 15.304 5.423 -13.888 1.00 20.94 ? 82 ASP A CG 1 ATOM 375 O OD1 . ASP A 1 50 ? 15.867 5.108 -12.814 1.00 22.44 ? 82 ASP A OD1 1 ATOM 376 O OD2 . ASP A 1 50 ? 14.282 4.840 -14.294 1.00 21.91 -1 82 ASP A OD2 1 ATOM 377 N N . SER A 1 51 ? 18.734 7.361 -14.415 1.00 19.05 ? 83 SER A N 1 ATOM 378 C CA . SER A 1 51 ? 20.117 7.819 -14.626 1.00 19.29 ? 83 SER A CA 1 ATOM 379 C C . SER A 1 51 ? 20.382 8.243 -16.063 1.00 19.96 ? 83 SER A C 1 ATOM 380 O O . SER A 1 51 ? 20.147 7.448 -16.972 1.00 20.62 ? 83 SER A O 1 ATOM 381 C CB . SER A 1 51 ? 21.099 6.680 -14.307 1.00 18.92 ? 83 SER A CB 1 ATOM 382 O OG . SER A 1 51 ? 20.964 6.177 -12.991 1.00 17.79 ? 83 SER A OG 1 ATOM 383 N N . PRO A 1 52 ? 20.873 9.477 -16.284 1.00 20.55 ? 84 PRO A N 1 ATOM 384 C CA . PRO A 1 52 ? 21.415 9.836 -17.608 1.00 20.66 ? 84 PRO A CA 1 ATOM 385 C C . PRO A 1 52 ? 22.709 9.154 -17.773 1.00 21.21 ? 84 PRO A C 1 ATOM 386 O O . PRO A 1 52 ? 23.375 8.945 -16.782 1.00 21.96 ? 84 PRO A O 1 ATOM 387 C CB . PRO A 1 52 ? 21.689 11.327 -17.509 1.00 20.69 ? 84 PRO A CB 1 ATOM 388 C CG . PRO A 1 52 ? 21.755 11.629 -16.050 1.00 21.22 ? 84 PRO A CG 1 ATOM 389 C CD . PRO A 1 52 ? 20.866 10.623 -15.361 1.00 21.14 ? 84 PRO A CD 1 ATOM 390 N N . TYR A 1 53 ? 23.095 8.839 -18.996 1.00 22.31 ? 85 TYR A N 1 ATOM 391 C CA . TYR A 1 53 ? 24.312 8.058 -19.219 1.00 23.40 ? 85 TYR A CA 1 ATOM 392 C C . TYR A 1 53 ? 25.551 8.593 -18.523 1.00 23.80 ? 85 TYR A C 1 ATOM 393 O O . TYR A 1 53 ? 26.420 7.846 -18.126 1.00 24.18 ? 85 TYR A O 1 ATOM 394 C CB . TYR A 1 53 ? 24.610 7.985 -20.696 1.00 24.40 ? 85 TYR A CB 1 ATOM 395 C CG . TYR A 1 53 ? 25.764 7.090 -21.008 1.00 25.83 ? 85 TYR A CG 1 ATOM 396 C CD1 . TYR A 1 53 ? 25.680 5.732 -20.755 1.00 26.55 ? 85 TYR A CD1 1 ATOM 397 C CD2 . TYR A 1 53 ? 26.947 7.593 -21.555 1.00 26.33 ? 85 TYR A CD2 1 ATOM 398 C CE1 . TYR A 1 53 ? 26.731 4.887 -21.045 1.00 27.50 ? 85 TYR A CE1 1 ATOM 399 C CE2 . TYR A 1 53 ? 28.010 6.754 -21.843 1.00 27.21 ? 85 TYR A CE2 1 ATOM 400 C CZ . TYR A 1 53 ? 27.890 5.397 -21.585 1.00 27.90 ? 85 TYR A CZ 1 ATOM 401 O OH . TYR A 1 53 ? 28.912 4.524 -21.860 1.00 29.58 ? 85 TYR A OH 1 ATOM 402 N N . GLN A 1 54 ? 25.629 9.892 -18.372 1.00 25.52 ? 86 GLN A N 1 ATOM 403 C CA . GLN A 1 54 ? 26.824 10.508 -17.861 1.00 29.20 ? 86 GLN A CA 1 ATOM 404 C C . GLN A 1 54 ? 27.011 10.340 -16.354 1.00 27.90 ? 86 GLN A C 1 ATOM 405 O O . GLN A 1 54 ? 28.112 10.494 -15.816 1.00 28.31 ? 86 GLN A O 1 ATOM 406 C CB . GLN A 1 54 ? 26.733 11.971 -18.191 1.00 34.29 ? 86 GLN A CB 1 ATOM 407 C CG . GLN A 1 54 ? 28.020 12.744 -18.071 1.00 39.88 ? 86 GLN A CG 1 ATOM 408 C CD . GLN A 1 54 ? 27.735 14.213 -18.301 1.00 48.17 ? 86 GLN A CD 1 ATOM 409 O OE1 . GLN A 1 54 ? 28.603 15.079 -18.118 1.00 56.46 ? 86 GLN A OE1 1 ATOM 410 N NE2 . GLN A 1 54 ? 26.490 14.513 -18.701 1.00 49.41 ? 86 GLN A NE2 1 ATOM 411 N N . LEU A 1 55 ? 25.914 10.083 -15.662 1.00 27.04 ? 87 LEU A N 1 ATOM 412 C CA . LEU A 1 55 ? 25.952 9.804 -14.231 1.00 25.04 ? 87 LEU A CA 1 ATOM 413 C C . LEU A 1 55 ? 26.566 8.432 -14.106 1.00 23.97 ? 87 LEU A C 1 ATOM 414 O O . LEU A 1 55 ? 27.556 8.259 -13.423 1.00 23.31 ? 87 LEU A O 1 ATOM 415 C CB . LEU A 1 55 ? 24.538 9.810 -13.653 1.00 24.48 ? 87 LEU A CB 1 ATOM 416 C CG . LEU A 1 55 ? 24.354 9.212 -12.271 1.00 24.12 ? 87 LEU A CG 1 ATOM 417 C CD1 . LEU A 1 55 ? 24.898 10.199 -11.278 1.00 24.69 ? 87 LEU A CD1 1 ATOM 418 C CD2 . LEU A 1 55 ? 22.901 8.933 -11.971 1.00 24.44 ? 87 LEU A CD2 1 ATOM 419 N N . ILE A 1 56 ? 25.984 7.473 -14.815 1.00 23.69 ? 88 ILE A N 1 ATOM 420 C CA . ILE A 1 56 ? 26.469 6.111 -14.810 1.00 24.41 ? 88 ILE A CA 1 ATOM 421 C C . ILE A 1 56 ? 27.935 6.098 -15.168 1.00 24.96 ? 88 ILE A C 1 ATOM 422 O O . ILE A 1 56 ? 28.729 5.296 -14.656 1.00 26.33 ? 88 ILE A O 1 ATOM 423 C CB . ILE A 1 56 ? 25.811 5.257 -15.890 1.00 25.81 ? 88 ILE A CB 1 ATOM 424 C CG1 . ILE A 1 56 ? 24.282 5.293 -15.808 1.00 27.02 ? 88 ILE A CG1 1 ATOM 425 C CG2 . ILE A 1 56 ? 26.319 3.825 -15.783 1.00 26.72 ? 88 ILE A CG2 1 ATOM 426 C CD1 . ILE A 1 56 ? 23.719 4.791 -14.502 1.00 28.00 ? 88 ILE A CD1 1 ATOM 427 N N . LEU A 1 57 ? 28.288 6.970 -16.096 1.00 24.14 ? 89 LEU A N 1 ATOM 428 C CA . LEU A 1 57 ? 29.642 7.016 -16.567 1.00 23.98 ? 89 LEU A CA 1 ATOM 429 C C . LEU A 1 57 ? 30.582 7.517 -15.489 1.00 23.09 ? 89 LEU A C 1 ATOM 430 O O . LEU A 1 57 ? 31.620 6.921 -15.249 1.00 23.32 ? 89 LEU A O 1 ATOM 431 C CB . LEU A 1 57 ? 29.725 7.917 -17.783 1.00 24.53 ? 89 LEU A CB 1 ATOM 432 C CG . LEU A 1 57 ? 30.904 7.671 -18.709 1.00 24.69 ? 89 LEU A CG 1 ATOM 433 C CD1 . LEU A 1 57 ? 30.936 6.213 -19.188 1.00 24.35 ? 89 LEU A CD1 1 ATOM 434 C CD2 . LEU A 1 57 ? 30.762 8.645 -19.869 1.00 24.81 ? 89 LEU A CD2 1 ATOM 435 N N . SER A 1 58 ? 30.203 8.610 -14.843 1.00 22.07 ? 90 SER A N 1 ATOM 436 C CA . SER A 1 58 ? 31.026 9.203 -13.815 1.00 21.89 ? 90 SER A CA 1 ATOM 437 C C . SER A 1 58 ? 31.197 8.263 -12.646 1.00 22.69 ? 90 SER A C 1 ATOM 438 O O . SER A 1 58 ? 32.216 8.275 -11.970 1.00 24.43 ? 90 SER A O 1 ATOM 439 C CB . SER A 1 58 ? 30.397 10.468 -13.302 1.00 21.21 ? 90 SER A CB 1 ATOM 440 O OG . SER A 1 58 ? 29.333 10.137 -12.460 1.00 21.08 ? 90 SER A OG 1 ATOM 441 N N . ALA A 1 59 ? 30.204 7.441 -12.392 1.00 22.75 ? 91 ALA A N 1 ATOM 442 C CA . ALA A 1 59 ? 30.358 6.479 -11.333 1.00 24.06 ? 91 ALA A CA 1 ATOM 443 C C . ALA A 1 59 ? 31.478 5.501 -11.661 1.00 23.98 ? 91 ALA A C 1 ATOM 444 O O . ALA A 1 59 ? 32.371 5.279 -10.832 1.00 24.03 ? 91 ALA A O 1 ATOM 445 C CB . ALA A 1 59 ? 29.056 5.746 -11.072 1.00 24.68 ? 91 ALA A CB 1 ATOM 446 N N . PHE A 1 60 ? 31.440 4.917 -12.852 1.00 24.34 ? 92 PHE A N 1 ATOM 447 C CA . PHE A 1 60 ? 32.543 4.030 -13.265 1.00 26.14 ? 92 PHE A CA 1 ATOM 448 C C . PHE A 1 60 ? 33.897 4.753 -13.448 1.00 28.28 ? 92 PHE A C 1 ATOM 449 O O . PHE A 1 60 ? 34.957 4.128 -13.308 1.00 28.74 ? 92 PHE A O 1 ATOM 450 C CB . PHE A 1 60 ? 32.215 3.296 -14.557 1.00 24.70 ? 92 PHE A CB 1 ATOM 451 C CG . PHE A 1 60 ? 31.198 2.224 -14.399 1.00 24.01 ? 92 PHE A CG 1 ATOM 452 C CD1 . PHE A 1 60 ? 31.419 1.168 -13.550 1.00 24.00 ? 92 PHE A CD1 1 ATOM 453 C CD2 . PHE A 1 60 ? 30.031 2.257 -15.123 1.00 24.15 ? 92 PHE A CD2 1 ATOM 454 C CE1 . PHE A 1 60 ? 30.486 0.159 -13.408 1.00 24.16 ? 92 PHE A CE1 1 ATOM 455 C CE2 . PHE A 1 60 ? 29.099 1.252 -14.999 1.00 24.12 ? 92 PHE A CE2 1 ATOM 456 C CZ . PHE A 1 60 ? 29.325 0.197 -14.142 1.00 24.15 ? 92 PHE A CZ 1 ATOM 457 N N . ASP A 1 61 ? 33.862 6.042 -13.788 1.00 28.90 ? 93 ASP A N 1 ATOM 458 C CA . ASP A 1 61 ? 35.082 6.781 -13.982 1.00 30.37 ? 93 ASP A CA 1 ATOM 459 C C . ASP A 1 61 ? 35.711 6.972 -12.636 1.00 32.26 ? 93 ASP A C 1 ATOM 460 O O . ASP A 1 61 ? 36.913 6.788 -12.500 1.00 37.70 ? 93 ASP A O 1 ATOM 461 C CB . ASP A 1 61 ? 34.841 8.133 -14.645 1.00 31.51 ? 93 ASP A CB 1 ATOM 462 C CG . ASP A 1 61 ? 34.663 8.029 -16.140 1.00 32.11 ? 93 ASP A CG 1 ATOM 463 O OD1 . ASP A 1 61 ? 35.243 7.090 -16.743 1.00 32.24 ? 93 ASP A OD1 1 ATOM 464 O OD2 . ASP A 1 61 ? 33.948 8.897 -16.700 1.00 32.49 -1 93 ASP A OD2 1 ATOM 465 N N . PHE A 1 62 ? 34.915 7.334 -11.634 1.00 32.03 ? 94 PHE A N 1 ATOM 466 C CA . PHE A 1 62 ? 35.435 7.424 -10.276 1.00 30.57 ? 94 PHE A CA 1 ATOM 467 C C . PHE A 1 62 ? 36.069 6.102 -9.850 1.00 28.91 ? 94 PHE A C 1 ATOM 468 O O . PHE A 1 62 ? 37.110 6.105 -9.231 1.00 29.44 ? 94 PHE A O 1 ATOM 469 C CB . PHE A 1 62 ? 34.350 7.817 -9.292 1.00 30.54 ? 94 PHE A CB 1 ATOM 470 C CG . PHE A 1 62 ? 34.767 7.695 -7.857 1.00 32.44 ? 94 PHE A CG 1 ATOM 471 C CD1 . PHE A 1 62 ? 35.480 8.715 -7.229 1.00 34.19 ? 94 PHE A CD1 1 ATOM 472 C CD2 . PHE A 1 62 ? 34.455 6.559 -7.120 1.00 34.06 ? 94 PHE A CD2 1 ATOM 473 C CE1 . PHE A 1 62 ? 35.858 8.608 -5.890 1.00 34.27 ? 94 PHE A CE1 1 ATOM 474 C CE2 . PHE A 1 62 ? 34.835 6.437 -5.781 1.00 34.49 ? 94 PHE A CE2 1 ATOM 475 C CZ . PHE A 1 62 ? 35.532 7.468 -5.165 1.00 34.60 ? 94 PHE A CZ 1 ATOM 476 N N . ILE A 1 63 ? 35.466 4.971 -10.169 1.00 27.75 ? 95 ILE A N 1 ATOM 477 C CA . ILE A 1 63 ? 36.075 3.734 -9.755 1.00 29.65 ? 95 ILE A CA 1 ATOM 478 C C . ILE A 1 63 ? 37.451 3.609 -10.374 1.00 33.57 ? 95 ILE A C 1 ATOM 479 O O . ILE A 1 63 ? 38.423 3.385 -9.674 1.00 36.35 ? 95 ILE A O 1 ATOM 480 C CB . ILE A 1 63 ? 35.236 2.503 -10.092 1.00 28.79 ? 95 ILE A CB 1 ATOM 481 C CG1 . ILE A 1 63 ? 34.062 2.402 -9.102 1.00 29.03 ? 95 ILE A CG1 1 ATOM 482 C CG2 . ILE A 1 63 ? 36.112 1.255 -10.015 1.00 27.77 ? 95 ILE A CG2 1 ATOM 483 C CD1 . ILE A 1 63 ? 32.975 1.397 -9.448 1.00 27.94 ? 95 ILE A CD1 1 ATOM 484 N N . LYS A 1 64 ? 37.535 3.757 -11.686 1.00 39.22 ? 96 LYS A N 1 ATOM 485 C CA . LYS A 1 64 ? 38.814 3.653 -12.412 1.00 41.69 ? 96 LYS A CA 1 ATOM 486 C C . LYS A 1 64 ? 39.849 4.659 -11.852 1.00 39.63 ? 96 LYS A C 1 ATOM 487 O O . LYS A 1 64 ? 40.946 4.284 -11.513 1.00 36.00 ? 96 LYS A O 1 ATOM 488 C CB . LYS A 1 64 ? 38.541 3.815 -13.920 1.00 46.76 ? 96 LYS A CB 1 ATOM 489 C CG . LYS A 1 64 ? 39.714 4.176 -14.824 1.00 53.43 ? 96 LYS A CG 1 ATOM 490 C CD . LYS A 1 64 ? 39.423 5.464 -15.618 1.00 57.34 ? 96 LYS A CD 1 ATOM 491 C CE . LYS A 1 64 ? 38.672 5.226 -16.925 1.00 58.03 ? 96 LYS A CE 1 ATOM 492 N NZ . LYS A 1 64 ? 39.519 5.402 -18.138 1.00 57.60 1 96 LYS A NZ 1 ATOM 493 N N . ASN A 1 65 ? 39.471 5.915 -11.688 1.00 42.34 ? 97 ASN A N 1 ATOM 494 C CA . ASN A 1 65 ? 40.332 6.922 -11.043 1.00 47.04 ? 97 ASN A CA 1 ATOM 495 C C . ASN A 1 65 ? 40.400 6.838 -9.516 1.00 48.66 ? 97 ASN A C 1 ATOM 496 O O . ASN A 1 65 ? 40.936 7.749 -8.880 1.00 52.10 ? 97 ASN A O 1 ATOM 497 C CB . ASN A 1 65 ? 39.822 8.340 -11.361 1.00 50.22 ? 97 ASN A CB 1 ATOM 498 C CG . ASN A 1 65 ? 40.121 8.787 -12.777 1.00 52.78 ? 97 ASN A CG 1 ATOM 499 O OD1 . ASN A 1 65 ? 40.177 9.991 -13.033 1.00 54.70 ? 97 ASN A OD1 1 ATOM 500 N ND2 . ASN A 1 65 ? 40.294 7.843 -13.707 1.00 54.36 ? 97 ASN A ND2 1 ATOM 501 N N . SER A 1 66 ? 39.849 5.786 -8.915 1.00 48.30 ? 98 SER A N 1 ATOM 502 C CA . SER A 1 66 ? 39.633 5.785 -7.464 1.00 45.48 ? 98 SER A CA 1 ATOM 503 C C . SER A 1 66 ? 40.941 5.778 -6.709 1.00 44.06 ? 98 SER A C 1 ATOM 504 O O . SER A 1 66 ? 41.108 6.492 -5.729 1.00 47.80 ? 98 SER A O 1 ATOM 505 C CB . SER A 1 66 ? 38.806 4.574 -7.016 1.00 43.28 ? 98 SER A CB 1 ATOM 506 O OG . SER A 1 66 ? 39.576 3.385 -7.009 1.00 42.08 ? 98 SER A OG 1 ATOM 507 N N . GLY A 1 67 ? 41.869 4.966 -7.177 1.00 42.19 ? 99 GLY A N 1 ATOM 508 C CA . GLY A 1 67 ? 43.072 4.696 -6.424 1.00 43.04 ? 99 GLY A CA 1 ATOM 509 C C . GLY A 1 67 ? 42.809 3.620 -5.402 1.00 41.09 ? 99 GLY A C 1 ATOM 510 O O . GLY A 1 67 ? 43.336 3.672 -4.297 1.00 47.84 ? 99 GLY A O 1 ATOM 511 N N . GLN A 1 68 ? 41.957 2.675 -5.772 1.00 38.39 ? 100 GLN A N 1 ATOM 512 C CA . GLN A 1 68 ? 41.704 1.479 -5.000 1.00 36.81 ? 100 GLN A CA 1 ATOM 513 C C . GLN A 1 68 ? 41.931 0.381 -5.992 1.00 36.98 ? 100 GLN A C 1 ATOM 514 O O . GLN A 1 68 ? 41.682 0.584 -7.158 1.00 37.55 ? 100 GLN A O 1 ATOM 515 C CB . GLN A 1 68 ? 40.247 1.436 -4.526 1.00 35.97 ? 100 GLN A CB 1 ATOM 516 C CG . GLN A 1 68 ? 39.825 2.564 -3.577 1.00 35.12 ? 100 GLN A CG 1 ATOM 517 C CD . GLN A 1 68 ? 40.053 2.264 -2.087 1.00 33.54 ? 100 GLN A CD 1 ATOM 518 O OE1 . GLN A 1 68 ? 40.595 1.212 -1.714 1.00 30.61 ? 100 GLN A OE1 1 ATOM 519 N NE2 . GLN A 1 68 ? 39.625 3.200 -1.225 1.00 32.08 ? 100 GLN A NE2 1 ATOM 520 N N . GLU A 1 69 ? 42.411 -0.766 -5.552 1.00 39.58 ? 101 GLU A N 1 ATOM 521 C CA . GLU A 1 69 ? 42.545 -1.912 -6.437 1.00 45.94 ? 101 GLU A CA 1 ATOM 522 C C . GLU A 1 69 ? 41.473 -2.930 -6.062 1.00 41.39 ? 101 GLU A C 1 ATOM 523 O O . GLU A 1 69 ? 41.058 -2.984 -4.914 1.00 43.22 ? 101 GLU A O 1 ATOM 524 C CB . GLU A 1 69 ? 43.961 -2.510 -6.330 1.00 57.84 ? 101 GLU A CB 1 ATOM 525 C CG . GLU A 1 69 ? 44.144 -3.725 -5.395 1.00 70.71 ? 101 GLU A CG 1 ATOM 526 C CD . GLU A 1 69 ? 43.982 -3.424 -3.899 1.00 80.95 ? 101 GLU A CD 1 ATOM 527 O OE1 . GLU A 1 69 ? 44.230 -2.264 -3.481 1.00 86.07 ? 101 GLU A OE1 1 ATOM 528 O OE2 . GLU A 1 69 ? 43.614 -4.361 -3.135 1.00 86.74 -1 101 GLU A OE2 1 ATOM 529 N N . ALA A 1 70 ? 41.021 -3.751 -6.996 1.00 35.39 ? 102 ALA A N 1 ATOM 530 C CA . ALA A 1 70 ? 39.976 -4.695 -6.640 1.00 33.30 ? 102 ALA A CA 1 ATOM 531 C C . ALA A 1 70 ? 40.071 -5.991 -7.405 1.00 31.30 ? 102 ALA A C 1 ATOM 532 O O . ALA A 1 70 ? 40.259 -5.995 -8.598 1.00 32.92 ? 102 ALA A O 1 ATOM 533 C CB . ALA A 1 70 ? 38.603 -4.063 -6.846 1.00 32.65 ? 102 ALA A CB 1 ATOM 534 N N . SER A 1 71 ? 39.903 -7.099 -6.712 1.00 29.42 ? 103 SER A N 1 ATOM 535 C CA . SER A 1 71 ? 39.927 -8.390 -7.350 1.00 28.31 ? 103 SER A CA 1 ATOM 536 C C . SER A 1 71 ? 38.725 -8.632 -8.232 1.00 27.29 ? 103 SER A C 1 ATOM 537 O O . SER A 1 71 ? 38.850 -9.313 -9.235 1.00 29.17 ? 103 SER A O 1 ATOM 538 C CB . SER A 1 71 ? 40.016 -9.456 -6.290 1.00 29.31 ? 103 SER A CB 1 ATOM 539 O OG . SER A 1 71 ? 41.137 -9.158 -5.476 1.00 31.47 ? 103 SER A OG 1 ATOM 540 N N . PHE A 1 72 ? 37.564 -8.088 -7.870 1.00 26.18 ? 104 PHE A N 1 ATOM 541 C CA . PHE A 1 72 ? 36.379 -8.172 -8.741 1.00 24.32 ? 104 PHE A CA 1 ATOM 542 C C . PHE A 1 72 ? 35.311 -7.103 -8.517 1.00 23.13 ? 104 PHE A C 1 ATOM 543 O O . PHE A 1 72 ? 35.560 -6.055 -7.911 1.00 22.34 ? 104 PHE A O 1 ATOM 544 C CB . PHE A 1 72 ? 35.765 -9.561 -8.670 1.00 23.75 ? 104 PHE A CB 1 ATOM 545 C CG . PHE A 1 72 ? 35.322 -9.949 -7.323 1.00 23.82 ? 104 PHE A CG 1 ATOM 546 C CD1 . PHE A 1 72 ? 36.228 -10.434 -6.409 1.00 24.02 ? 104 PHE A CD1 1 ATOM 547 C CD2 . PHE A 1 72 ? 33.998 -9.865 -6.969 1.00 24.71 ? 104 PHE A CD2 1 ATOM 548 C CE1 . PHE A 1 72 ? 35.823 -10.818 -5.144 1.00 23.72 ? 104 PHE A CE1 1 ATOM 549 C CE2 . PHE A 1 72 ? 33.581 -10.257 -5.706 1.00 24.63 ? 104 PHE A CE2 1 ATOM 550 C CZ . PHE A 1 72 ? 34.499 -10.728 -4.792 1.00 23.87 ? 104 PHE A CZ 1 ATOM 551 N N . MET A 1 73 ? 34.147 -7.349 -9.106 1.00 22.66 ? 105 MET A N 1 ATOM 552 C CA . MET A 1 73 ? 32.999 -6.467 -8.994 1.00 22.28 ? 105 MET A CA 1 ATOM 553 C C . MET A 1 73 ? 31.750 -7.309 -9.061 1.00 20.67 ? 105 MET A C 1 ATOM 554 O O . MET A 1 73 ? 31.685 -8.306 -9.762 1.00 20.23 ? 105 MET A O 1 ATOM 555 C CB . MET A 1 73 ? 32.985 -5.422 -10.116 1.00 22.84 ? 105 MET A CB 1 ATOM 556 C CG . MET A 1 73 ? 31.803 -4.451 -10.112 1.00 23.67 ? 105 MET A CG 1 ATOM 557 S SD . MET A 1 73 ? 31.820 -3.294 -11.513 1.00 25.70 ? 105 MET A SD 1 ATOM 558 C CE . MET A 1 73 ? 32.974 -2.048 -10.962 1.00 25.93 ? 105 MET A CE 1 ATOM 559 N N . ILE A 1 74 ? 30.774 -6.889 -8.284 1.00 19.96 ? 106 ILE A N 1 ATOM 560 C CA A ILE A 1 74 ? 29.471 -7.511 -8.202 0.50 19.98 ? 106 ILE A CA 1 ATOM 561 C CA B ILE A 1 74 ? 29.483 -7.547 -8.288 0.50 19.66 ? 106 ILE A CA 1 ATOM 562 C C . ILE A 1 74 ? 28.466 -6.546 -8.823 1.00 20.07 ? 106 ILE A C 1 ATOM 563 O O . ILE A 1 74 ? 28.470 -5.356 -8.464 1.00 20.17 ? 106 ILE A O 1 ATOM 564 C CB A ILE A 1 74 ? 29.133 -7.725 -6.717 0.50 19.92 ? 106 ILE A CB 1 ATOM 565 C CB B ILE A 1 74 ? 29.086 -8.113 -6.902 0.50 19.15 ? 106 ILE A CB 1 ATOM 566 C CG1 A ILE A 1 74 ? 29.959 -8.871 -6.172 0.50 19.70 ? 106 ILE A CG1 1 ATOM 567 C CG1 B ILE A 1 74 ? 29.154 -7.055 -5.798 0.50 19.01 ? 106 ILE A CG1 1 ATOM 568 C CG2 A ILE A 1 74 ? 27.657 -7.994 -6.511 0.50 20.10 ? 106 ILE A CG2 1 ATOM 569 C CG2 B ILE A 1 74 ? 29.993 -9.261 -6.519 0.50 18.93 ? 106 ILE A CG2 1 ATOM 570 C CD1 A ILE A 1 74 ? 30.072 -9.989 -7.170 0.50 19.91 ? 106 ILE A CD1 1 ATOM 571 C CD1 B ILE A 1 74 ? 28.387 -7.450 -4.558 0.50 18.88 ? 106 ILE A CD1 1 ATOM 572 N N . TRP A 1 75 ? 27.605 -7.020 -9.716 1.00 20.09 ? 107 TRP A N 1 ATOM 573 C CA . TRP A 1 75 ? 26.665 -6.123 -10.361 1.00 21.36 ? 107 TRP A CA 1 ATOM 574 C C . TRP A 1 75 ? 25.260 -6.676 -10.295 1.00 20.75 ? 107 TRP A C 1 ATOM 575 O O . TRP A 1 75 ? 24.922 -7.579 -11.035 1.00 21.18 ? 107 TRP A O 1 ATOM 576 C CB . TRP A 1 75 ? 27.103 -5.938 -11.791 1.00 23.15 ? 107 TRP A CB 1 ATOM 577 C CG . TRP A 1 75 ? 26.219 -5.095 -12.608 1.00 25.71 ? 107 TRP A CG 1 ATOM 578 C CD1 . TRP A 1 75 ? 25.399 -4.101 -12.175 1.00 27.04 ? 107 TRP A CD1 1 ATOM 579 C CD2 . TRP A 1 75 ? 26.112 -5.115 -14.040 1.00 27.41 ? 107 TRP A CD2 1 ATOM 580 N NE1 . TRP A 1 75 ? 24.752 -3.516 -13.251 1.00 28.52 ? 107 TRP A NE1 1 ATOM 581 C CE2 . TRP A 1 75 ? 25.183 -4.118 -14.407 1.00 27.78 ? 107 TRP A CE2 1 ATOM 582 C CE3 . TRP A 1 75 ? 26.716 -5.877 -15.047 1.00 27.98 ? 107 TRP A CE3 1 ATOM 583 C CZ2 . TRP A 1 75 ? 24.836 -3.869 -15.741 1.00 27.35 ? 107 TRP A CZ2 1 ATOM 584 C CZ3 . TRP A 1 75 ? 26.359 -5.632 -16.371 1.00 28.32 ? 107 TRP A CZ3 1 ATOM 585 C CH2 . TRP A 1 75 ? 25.429 -4.631 -16.701 1.00 27.45 ? 107 TRP A CH2 1 ATOM 586 N N . THR A 1 76 ? 24.416 -6.124 -9.432 1.00 20.40 ? 108 THR A N 1 ATOM 587 C CA . THR A 1 76 ? 23.141 -6.796 -9.135 1.00 20.40 ? 108 THR A CA 1 ATOM 588 C C . THR A 1 76 ? 21.917 -6.340 -9.946 1.00 20.38 ? 108 THR A C 1 ATOM 589 O O . THR A 1 76 ? 20.788 -6.534 -9.504 1.00 21.25 ? 108 THR A O 1 ATOM 590 C CB . THR A 1 76 ? 22.804 -6.718 -7.637 1.00 19.82 ? 108 THR A CB 1 ATOM 591 O OG1 . THR A 1 76 ? 22.888 -5.366 -7.214 1.00 19.16 ? 108 THR A OG1 1 ATOM 592 C CG2 . THR A 1 76 ? 23.773 -7.535 -6.846 1.00 19.80 ? 108 THR A CG2 1 ATOM 593 N N . GLY A 1 77 ? 22.134 -5.756 -11.121 1.00 19.84 ? 109 GLY A N 1 ATOM 594 C CA . GLY A 1 77 ? 21.099 -5.692 -12.142 1.00 19.20 ? 109 GLY A CA 1 ATOM 595 C C . GLY A 1 77 ? 20.301 -4.410 -12.187 1.00 18.39 ? 109 GLY A C 1 ATOM 596 O O . GLY A 1 77 ? 20.799 -3.361 -11.781 1.00 18.74 ? 109 GLY A O 1 ATOM 597 N N . ASP A 1 78 ? 19.061 -4.526 -12.699 1.00 17.33 ? 110 ASP A N 1 ATOM 598 C CA . ASP A 1 78 ? 18.124 -3.398 -12.962 1.00 16.41 ? 110 ASP A CA 1 ATOM 599 C C . ASP A 1 78 ? 18.738 -2.277 -13.795 1.00 15.64 ? 110 ASP A C 1 ATOM 600 O O . ASP A 1 78 ? 19.078 -1.209 -13.265 1.00 14.97 ? 110 ASP A O 1 ATOM 601 C CB . ASP A 1 78 ? 17.546 -2.827 -11.649 1.00 16.45 ? 110 ASP A CB 1 ATOM 602 C CG . ASP A 1 78 ? 16.234 -3.504 -11.215 1.00 15.91 ? 110 ASP A CG 1 ATOM 603 O OD1 . ASP A 1 78 ? 15.879 -4.572 -11.763 1.00 15.17 ? 110 ASP A OD1 1 ATOM 604 O OD2 . ASP A 1 78 ? 15.587 -2.968 -10.288 1.00 15.43 -1 110 ASP A OD2 1 ATOM 605 N N . SER A 1 79 ? 18.880 -2.537 -15.094 1.00 15.28 ? 111 SER A N 1 ATOM 606 C CA . SER A 1 79 ? 19.556 -1.601 -16.000 1.00 15.37 ? 111 SER A CA 1 ATOM 607 C C . SER A 1 79 ? 18.634 -0.741 -16.846 1.00 14.96 ? 111 SER A C 1 ATOM 608 O O . SER A 1 79 ? 18.914 0.448 -17.053 1.00 15.21 ? 111 SER A O 1 ATOM 609 C CB . SER A 1 79 ? 20.549 -2.347 -16.878 1.00 15.72 ? 111 SER A CB 1 ATOM 610 O OG . SER A 1 79 ? 21.583 -2.891 -16.080 1.00 16.74 ? 111 SER A OG 1 ATOM 611 N N . PRO A 1 80 ? 17.539 -1.328 -17.354 1.00 14.82 ? 112 PRO A N 1 ATOM 612 C CA . PRO A 1 80 ? 16.525 -0.513 -18.018 1.00 14.68 ? 112 PRO A CA 1 ATOM 613 C C . PRO A 1 80 ? 15.792 0.423 -17.066 1.00 14.61 ? 112 PRO A C 1 ATOM 614 O O . PRO A 1 80 ? 15.587 0.078 -15.909 1.00 14.37 ? 112 PRO A O 1 ATOM 615 C CB . PRO A 1 80 ? 15.531 -1.548 -18.519 1.00 14.67 ? 112 PRO A CB 1 ATOM 616 C CG . PRO A 1 80 ? 16.336 -2.777 -18.665 1.00 14.84 ? 112 PRO A CG 1 ATOM 617 C CD . PRO A 1 80 ? 17.225 -2.760 -17.478 1.00 14.89 ? 112 PRO A CD 1 ATOM 618 N N . PRO A 1 81 ? 15.325 1.564 -17.574 1.00 14.53 ? 113 PRO A N 1 ATOM 619 C CA . PRO A 1 81 ? 14.648 2.545 -16.749 1.00 14.46 ? 113 PRO A CA 1 ATOM 620 C C . PRO A 1 81 ? 13.183 2.213 -16.430 1.00 14.59 ? 113 PRO A C 1 ATOM 621 O O . PRO A 1 81 ? 12.610 1.220 -16.922 1.00 14.53 ? 113 PRO A O 1 ATOM 622 C CB . PRO A 1 81 ? 14.697 3.797 -17.615 1.00 14.63 ? 113 PRO A CB 1 ATOM 623 C CG . PRO A 1 81 ? 14.667 3.269 -19.019 1.00 14.77 ? 113 PRO A CG 1 ATOM 624 C CD . PRO A 1 81 ? 15.121 1.834 -19.006 1.00 14.44 ? 113 PRO A CD 1 ATOM 625 N N . HIS A 1 82 ? 12.612 3.074 -15.592 1.00 14.60 ? 114 HIS A N 1 ATOM 626 C CA . HIS A 1 82 ? 11.242 2.980 -15.122 1.00 14.57 ? 114 HIS A CA 1 ATOM 627 C C . HIS A 1 82 ? 10.358 3.794 -16.057 1.00 14.66 ? 114 HIS A C 1 ATOM 628 O O . HIS A 1 82 ? 10.178 5.018 -15.910 1.00 13.50 ? 114 HIS A O 1 ATOM 629 C CB . HIS A 1 82 ? 11.113 3.531 -13.694 1.00 14.95 ? 114 HIS A CB 1 ATOM 630 C CG . HIS A 1 82 ? 11.901 2.780 -12.677 1.00 14.90 ? 114 HIS A CG 1 ATOM 631 N ND1 . HIS A 1 82 ? 13.242 3.006 -12.465 1.00 15.35 ? 114 HIS A ND1 1 ATOM 632 C CD2 . HIS A 1 82 ? 11.541 1.794 -11.818 1.00 15.16 ? 114 HIS A CD2 1 ATOM 633 C CE1 . HIS A 1 82 ? 13.679 2.182 -11.525 1.00 15.72 ? 114 HIS A CE1 1 ATOM 634 N NE2 . HIS A 1 82 ? 12.661 1.444 -11.108 1.00 15.38 ? 114 HIS A NE2 1 ATOM 635 N N . VAL A 1 83 ? 9.833 3.081 -17.041 1.00 15.47 ? 115 VAL A N 1 ATOM 636 C CA . VAL A 1 83 ? 8.818 3.586 -17.940 1.00 15.93 ? 115 VAL A CA 1 ATOM 637 C C . VAL A 1 83 ? 7.843 2.429 -18.171 1.00 17.11 ? 115 VAL A C 1 ATOM 638 O O . VAL A 1 83 ? 8.187 1.246 -17.964 1.00 17.23 ? 115 VAL A O 1 ATOM 639 C CB . VAL A 1 83 ? 9.435 4.074 -19.266 1.00 15.47 ? 115 VAL A CB 1 ATOM 640 C CG1 . VAL A 1 83 ? 10.478 5.168 -19.040 1.00 15.20 ? 115 VAL A CG1 1 ATOM 641 C CG2 . VAL A 1 83 ? 10.103 2.932 -19.959 1.00 15.77 ? 115 VAL A CG2 1 ATOM 642 N N . PRO A 1 84 ? 6.621 2.746 -18.587 1.00 18.93 ? 116 PRO A N 1 ATOM 643 C CA . PRO A 1 84 ? 5.601 1.709 -18.753 1.00 19.71 ? 116 PRO A CA 1 ATOM 644 C C . PRO A 1 84 ? 5.922 0.751 -19.875 1.00 20.95 ? 116 PRO A C 1 ATOM 645 O O . PRO A 1 84 ? 6.596 1.136 -20.856 1.00 19.77 ? 116 PRO A O 1 ATOM 646 C CB . PRO A 1 84 ? 4.351 2.487 -19.115 1.00 19.86 ? 116 PRO A CB 1 ATOM 647 C CG . PRO A 1 84 ? 4.656 3.925 -18.838 1.00 20.10 ? 116 PRO A CG 1 ATOM 648 C CD . PRO A 1 84 ? 6.135 4.073 -18.980 1.00 19.71 ? 116 PRO A CD 1 ATOM 649 N N . VAL A 1 85 ? 5.412 -0.474 -19.713 1.00 22.94 ? 117 VAL A N 1 ATOM 650 C CA . VAL A 1 85 ? 5.723 -1.620 -20.590 1.00 24.75 ? 117 VAL A CA 1 ATOM 651 C C . VAL A 1 85 ? 5.624 -1.329 -22.081 1.00 25.94 ? 117 VAL A C 1 ATOM 652 O O . VAL A 1 85 ? 6.590 -1.561 -22.806 1.00 25.05 ? 117 VAL A O 1 ATOM 653 C CB . VAL A 1 85 ? 4.821 -2.829 -20.317 1.00 25.70 ? 117 VAL A CB 1 ATOM 654 C CG1 . VAL A 1 85 ? 5.159 -3.945 -21.291 1.00 26.77 ? 117 VAL A CG1 1 ATOM 655 C CG2 . VAL A 1 85 ? 4.980 -3.314 -18.884 1.00 26.77 ? 117 VAL A CG2 1 ATOM 656 N N . PRO A 1 86 ? 4.462 -0.821 -22.544 1.00 28.78 ? 118 PRO A N 1 ATOM 657 C CA . PRO A 1 86 ? 4.306 -0.502 -23.973 1.00 29.60 ? 118 PRO A CA 1 ATOM 658 C C . PRO A 1 86 ? 5.392 0.401 -24.501 1.00 29.63 ? 118 PRO A C 1 ATOM 659 O O . PRO A 1 86 ? 5.837 0.217 -25.607 1.00 29.69 ? 118 PRO A O 1 ATOM 660 C CB . PRO A 1 86 ? 2.965 0.227 -24.048 1.00 30.43 ? 118 PRO A CB 1 ATOM 661 C CG . PRO A 1 86 ? 2.270 -0.020 -22.743 1.00 30.22 ? 118 PRO A CG 1 ATOM 662 C CD . PRO A 1 86 ? 3.327 -0.324 -21.738 1.00 29.89 ? 118 PRO A CD 1 ATOM 663 N N . GLU A 1 87 ? 5.838 1.362 -23.710 1.00 32.38 ? 119 GLU A N 1 ATOM 664 C CA . GLU A 1 87 ? 6.981 2.181 -24.123 1.00 33.72 ? 119 GLU A CA 1 ATOM 665 C C . GLU A 1 87 ? 8.298 1.421 -24.295 1.00 29.66 ? 119 GLU A C 1 ATOM 666 O O . GLU A 1 87 ? 9.238 1.964 -24.841 1.00 27.84 ? 119 GLU A O 1 ATOM 667 C CB . GLU A 1 87 ? 7.192 3.349 -23.163 1.00 38.03 ? 119 GLU A CB 1 ATOM 668 C CG . GLU A 1 87 ? 6.659 4.659 -23.710 1.00 43.55 ? 119 GLU A CG 1 ATOM 669 C CD . GLU A 1 87 ? 7.260 5.854 -22.992 1.00 48.33 ? 119 GLU A CD 1 ATOM 670 O OE1 . GLU A 1 87 ? 8.124 6.550 -23.616 1.00 52.17 ? 119 GLU A OE1 1 ATOM 671 O OE2 . GLU A 1 87 ? 6.876 6.071 -21.808 1.00 45.22 -1 119 GLU A OE2 1 ATOM 672 N N . LEU A 1 88 ? 8.372 0.178 -23.850 1.00 27.54 ? 120 LEU A N 1 ATOM 673 C CA . LEU A 1 88 ? 9.613 -0.584 -23.949 1.00 27.98 ? 120 LEU A CA 1 ATOM 674 C C . LEU A 1 88 ? 9.506 -1.900 -24.731 1.00 26.06 ? 120 LEU A C 1 ATOM 675 O O . LEU A 1 88 ? 8.428 -2.302 -25.120 1.00 27.67 ? 120 LEU A O 1 ATOM 676 C CB . LEU A 1 88 ? 10.067 -0.926 -22.541 1.00 29.33 ? 120 LEU A CB 1 ATOM 677 C CG . LEU A 1 88 ? 10.743 0.152 -21.728 1.00 28.64 ? 120 LEU A CG 1 ATOM 678 C CD1 . LEU A 1 88 ? 11.085 -0.500 -20.399 1.00 29.36 ? 120 LEU A CD1 1 ATOM 679 C CD2 . LEU A 1 88 ? 11.988 0.702 -22.423 1.00 28.67 ? 120 LEU A CD2 1 ATOM 680 N N . SER A 1 89 ? 10.615 -2.599 -24.901 1.00 23.41 ? 121 SER A N 1 ATOM 681 C CA . SER A 1 89 ? 10.567 -3.893 -25.522 1.00 23.50 ? 121 SER A CA 1 ATOM 682 C C . SER A 1 89 ? 11.754 -4.737 -25.128 1.00 23.92 ? 121 SER A C 1 ATOM 683 O O . SER A 1 89 ? 12.774 -4.205 -24.667 1.00 24.27 ? 121 SER A O 1 ATOM 684 C CB . SER A 1 89 ? 10.614 -3.719 -27.026 1.00 23.91 ? 121 SER A CB 1 ATOM 685 O OG . SER A 1 89 ? 11.943 -3.505 -27.477 1.00 23.19 ? 121 SER A OG 1 ATOM 686 N N . THR A 1 90 ? 11.644 -6.041 -25.383 1.00 22.94 ? 122 THR A N 1 ATOM 687 C CA . THR A 1 90 ? 12.774 -6.963 -25.240 1.00 22.22 ? 122 THR A CA 1 ATOM 688 C C . THR A 1 90 ? 14.047 -6.453 -25.920 1.00 25.10 ? 122 THR A C 1 ATOM 689 O O . THR A 1 90 ? 15.148 -6.562 -25.383 1.00 27.94 ? 122 THR A O 1 ATOM 690 C CB . THR A 1 90 ? 12.425 -8.333 -25.816 1.00 20.53 ? 122 THR A CB 1 ATOM 691 O OG1 . THR A 1 90 ? 11.388 -8.906 -25.034 1.00 20.01 ? 122 THR A OG1 1 ATOM 692 C CG2 . THR A 1 90 ? 13.585 -9.260 -25.786 1.00 20.07 ? 122 THR A CG2 1 ATOM 693 N N . ASP A 1 91 ? 13.923 -5.885 -27.103 1.00 28.01 ? 123 ASP A N 1 ATOM 694 C CA . ASP A 1 91 ? 15.129 -5.466 -27.810 1.00 29.82 ? 123 ASP A CA 1 ATOM 695 C C . ASP A 1 91 ? 15.740 -4.238 -27.148 1.00 28.32 ? 123 ASP A C 1 ATOM 696 O O . ASP A 1 91 ? 16.950 -4.122 -27.107 1.00 28.28 ? 123 ASP A O 1 ATOM 697 C CB . ASP A 1 91 ? 14.867 -5.266 -29.319 1.00 32.23 ? 123 ASP A CB 1 ATOM 698 C CG . ASP A 1 91 ? 14.806 -6.614 -30.111 1.00 33.06 ? 123 ASP A CG 1 ATOM 699 O OD1 . ASP A 1 91 ? 14.272 -7.668 -29.638 1.00 32.71 ? 123 ASP A OD1 1 ATOM 700 O OD2 . ASP A 1 91 ? 15.300 -6.600 -31.250 1.00 34.65 -1 123 ASP A OD2 1 ATOM 701 N N . THR A 1 92 ? 14.920 -3.354 -26.591 1.00 27.71 ? 124 THR A N 1 ATOM 702 C CA . THR A 1 92 ? 15.451 -2.182 -25.899 1.00 29.17 ? 124 THR A CA 1 ATOM 703 C C . THR A 1 92 ? 16.138 -2.601 -24.604 1.00 29.92 ? 124 THR A C 1 ATOM 704 O O . THR A 1 92 ? 17.227 -2.097 -24.248 1.00 30.45 ? 124 THR A O 1 ATOM 705 C CB . THR A 1 92 ? 14.354 -1.202 -25.490 1.00 29.51 ? 124 THR A CB 1 ATOM 706 O OG1 . THR A 1 92 ? 13.196 -1.437 -26.278 1.00 32.50 ? 124 THR A OG1 1 ATOM 707 C CG2 . THR A 1 92 ? 14.811 0.213 -25.687 1.00 30.06 ? 124 THR A CG2 1 ATOM 708 N N . VAL A 1 93 ? 15.480 -3.498 -23.879 1.00 28.02 ? 125 VAL A N 1 ATOM 709 C CA . VAL A 1 93 ? 16.062 -4.040 -22.676 1.00 26.67 ? 125 VAL A CA 1 ATOM 710 C C . VAL A 1 93 ? 17.495 -4.496 -23.009 1.00 27.26 ? 125 VAL A C 1 ATOM 711 O O . VAL A 1 93 ? 18.471 -4.066 -22.358 1.00 28.05 ? 125 VAL A O 1 ATOM 712 C CB . VAL A 1 93 ? 15.184 -5.173 -22.119 1.00 26.36 ? 125 VAL A CB 1 ATOM 713 C CG1 . VAL A 1 93 ? 15.996 -6.187 -21.329 1.00 27.55 ? 125 VAL A CG1 1 ATOM 714 C CG2 . VAL A 1 93 ? 14.076 -4.602 -21.253 1.00 25.96 ? 125 VAL A CG2 1 ATOM 715 N N . ILE A 1 94 ? 17.623 -5.309 -24.056 1.00 25.45 ? 126 ILE A N 1 ATOM 716 C CA . ILE A 1 94 ? 18.906 -5.894 -24.409 1.00 24.25 ? 126 ILE A CA 1 ATOM 717 C C . ILE A 1 94 ? 19.916 -4.835 -24.853 1.00 23.75 ? 126 ILE A C 1 ATOM 718 O O . ILE A 1 94 ? 21.087 -4.895 -24.495 1.00 21.68 ? 126 ILE A O 1 ATOM 719 C CB . ILE A 1 94 ? 18.708 -7.004 -25.453 1.00 24.30 ? 126 ILE A CB 1 ATOM 720 C CG1 . ILE A 1 94 ? 17.906 -8.119 -24.797 1.00 25.91 ? 126 ILE A CG1 1 ATOM 721 C CG2 . ILE A 1 94 ? 20.035 -7.562 -25.956 1.00 23.43 ? 126 ILE A CG2 1 ATOM 722 C CD1 . ILE A 1 94 ? 17.531 -9.271 -25.703 1.00 26.64 ? 126 ILE A CD1 1 ATOM 723 N N . ASN A 1 95 ? 19.470 -3.840 -25.597 1.00 25.23 ? 127 ASN A N 1 ATOM 724 C CA . ASN A 1 95 ? 20.394 -2.790 -25.990 1.00 28.08 ? 127 ASN A CA 1 ATOM 725 C C . ASN A 1 95 ? 20.929 -2.100 -24.757 1.00 28.52 ? 127 ASN A C 1 ATOM 726 O O . ASN A 1 95 ? 22.137 -1.857 -24.660 1.00 29.78 ? 127 ASN A O 1 ATOM 727 C CB . ASN A 1 95 ? 19.744 -1.762 -26.894 1.00 30.81 ? 127 ASN A CB 1 ATOM 728 C CG . ASN A 1 95 ? 19.170 -2.373 -28.151 1.00 33.81 ? 127 ASN A CG 1 ATOM 729 O OD1 . ASN A 1 95 ? 19.694 -3.358 -28.692 1.00 35.38 ? 127 ASN A OD1 1 ATOM 730 N ND2 . ASN A 1 95 ? 18.053 -1.809 -28.611 1.00 37.39 ? 127 ASN A ND2 1 ATOM 731 N N . VAL A 1 96 ? 20.045 -1.821 -23.798 1.00 27.36 ? 128 VAL A N 1 ATOM 732 C CA . VAL A 1 96 ? 20.484 -1.239 -22.518 1.00 26.10 ? 128 VAL A CA 1 ATOM 733 C C . VAL A 1 96 ? 21.416 -2.117 -21.683 1.00 23.49 ? 128 VAL A C 1 ATOM 734 O O . VAL A 1 96 ? 22.432 -1.656 -21.207 1.00 21.97 ? 128 VAL A O 1 ATOM 735 C CB . VAL A 1 96 ? 19.301 -0.807 -21.663 1.00 26.96 ? 128 VAL A CB 1 ATOM 736 C CG1 . VAL A 1 96 ? 19.754 -0.416 -20.265 1.00 27.31 ? 128 VAL A CG1 1 ATOM 737 C CG2 . VAL A 1 96 ? 18.633 0.381 -22.332 1.00 28.31 ? 128 VAL A CG2 1 ATOM 738 N N . ILE A 1 97 ? 21.093 -3.380 -21.502 1.00 22.43 ? 129 ILE A N 1 ATOM 739 C CA . ILE A 1 97 ? 22.039 -4.235 -20.812 1.00 22.36 ? 129 ILE A CA 1 ATOM 740 C C . ILE A 1 97 ? 23.364 -4.252 -21.583 1.00 23.84 ? 129 ILE A C 1 ATOM 741 O O . ILE A 1 97 ? 24.456 -4.176 -20.985 1.00 23.51 ? 129 ILE A O 1 ATOM 742 C CB . ILE A 1 97 ? 21.496 -5.656 -20.648 1.00 21.50 ? 129 ILE A CB 1 ATOM 743 C CG1 . ILE A 1 97 ? 20.250 -5.634 -19.753 1.00 21.42 ? 129 ILE A CG1 1 ATOM 744 C CG2 . ILE A 1 97 ? 22.564 -6.557 -20.048 1.00 21.03 ? 129 ILE A CG2 1 ATOM 745 C CD1 . ILE A 1 97 ? 19.590 -6.987 -19.553 1.00 21.53 ? 129 ILE A CD1 1 ATOM 746 N N . THR A 1 98 ? 23.269 -4.336 -22.911 1.00 24.84 ? 130 THR A N 1 ATOM 747 C CA . THR A 1 98 ? 24.460 -4.434 -23.746 1.00 26.08 ? 130 THR A CA 1 ATOM 748 C C . THR A 1 98 ? 25.359 -3.209 -23.523 1.00 25.54 ? 130 THR A C 1 ATOM 749 O O . THR A 1 98 ? 26.566 -3.355 -23.333 1.00 24.46 ? 130 THR A O 1 ATOM 750 C CB . THR A 1 98 ? 24.097 -4.598 -25.253 1.00 27.40 ? 130 THR A CB 1 ATOM 751 O OG1 . THR A 1 98 ? 23.270 -5.757 -25.438 1.00 27.93 ? 130 THR A OG1 1 ATOM 752 C CG2 . THR A 1 98 ? 25.357 -4.745 -26.133 1.00 26.73 ? 130 THR A CG2 1 ATOM 753 N N . ASN A 1 99 ? 24.770 -2.011 -23.523 1.00 25.49 ? 131 ASN A N 1 ATOM 754 C CA . ASN A 1 99 ? 25.547 -0.774 -23.347 1.00 25.90 ? 131 ASN A CA 1 ATOM 755 C C . ASN A 1 99 ? 26.312 -0.832 -22.026 1.00 25.50 ? 131 ASN A C 1 ATOM 756 O O . ASN A 1 99 ? 27.536 -0.738 -22.008 1.00 26.59 ? 131 ASN A O 1 ATOM 757 C CB . ASN A 1 99 ? 24.650 0.475 -23.435 1.00 27.15 ? 131 ASN A CB 1 ATOM 758 C CG . ASN A 1 99 ? 25.442 1.781 -23.380 1.00 30.34 ? 131 ASN A CG 1 ATOM 759 O OD1 . ASN A 1 99 ? 26.264 1.956 -22.481 1.00 32.51 ? 131 ASN A OD1 1 ATOM 760 N ND2 . ASN A 1 99 ? 25.178 2.729 -24.325 1.00 33.36 ? 131 ASN A ND2 1 ATOM 761 N N . MET A 1 100 ? 25.590 -1.028 -20.926 1.00 25.02 ? 132 MET A N 1 ATOM 762 C CA . MET A 1 100 ? 26.205 -1.227 -19.607 1.00 23.92 ? 132 MET A CA 1 ATOM 763 C C . MET A 1 100 ? 27.331 -2.275 -19.691 1.00 23.11 ? 132 MET A C 1 ATOM 764 O O . MET A 1 100 ? 28.506 -1.948 -19.470 1.00 21.96 ? 132 MET A O 1 ATOM 765 C CB . MET A 1 100 ? 25.151 -1.650 -18.571 1.00 23.39 ? 132 MET A CB 1 ATOM 766 C CG . MET A 1 100 ? 24.031 -0.646 -18.356 1.00 23.12 ? 132 MET A CG 1 ATOM 767 S SD . MET A 1 100 ? 24.575 0.944 -17.689 1.00 24.37 ? 132 MET A SD 1 ATOM 768 C CE . MET A 1 100 ? 24.732 2.016 -19.100 1.00 24.39 ? 132 MET A CE 1 ATOM 769 N N . THR A 1 101 ? 26.983 -3.508 -20.059 1.00 21.97 ? 133 THR A N 1 ATOM 770 C CA . THR A 1 101 ? 27.978 -4.556 -20.128 1.00 22.01 ? 133 THR A CA 1 ATOM 771 C C . THR A 1 101 ? 29.177 -4.147 -20.955 1.00 23.55 ? 133 THR A C 1 ATOM 772 O O . THR A 1 101 ? 30.300 -4.336 -20.543 1.00 24.95 ? 133 THR A O 1 ATOM 773 C CB . THR A 1 101 ? 27.455 -5.837 -20.745 1.00 21.51 ? 133 THR A CB 1 ATOM 774 O OG1 . THR A 1 101 ? 26.279 -6.284 -20.056 1.00 21.12 ? 133 THR A OG1 1 ATOM 775 C CG2 . THR A 1 101 ? 28.534 -6.888 -20.653 1.00 21.27 ? 133 THR A CG2 1 ATOM 776 N N . THR A 1 102 ? 28.961 -3.591 -22.130 1.00 25.92 ? 134 THR A N 1 ATOM 777 C CA . THR A 1 102 ? 30.087 -3.078 -22.894 1.00 28.53 ? 134 THR A CA 1 ATOM 778 C C . THR A 1 102 ? 30.849 -1.977 -22.144 1.00 30.16 ? 134 THR A C 1 ATOM 779 O O . THR A 1 102 ? 32.053 -2.132 -21.912 1.00 33.09 ? 134 THR A O 1 ATOM 780 C CB . THR A 1 102 ? 29.651 -2.549 -24.253 1.00 29.11 ? 134 THR A CB 1 ATOM 781 O OG1 . THR A 1 102 ? 28.946 -3.594 -24.916 1.00 27.93 ? 134 THR A OG1 1 ATOM 782 C CG2 . THR A 1 102 ? 30.871 -2.110 -25.084 1.00 29.30 ? 134 THR A CG2 1 ATOM 783 N N . THR A 1 103 ? 30.160 -0.898 -21.757 1.00 29.10 ? 135 THR A N 1 ATOM 784 C CA . THR A 1 103 ? 30.796 0.226 -21.046 1.00 29.08 ? 135 THR A CA 1 ATOM 785 C C . THR A 1 103 ? 31.746 -0.199 -19.914 1.00 29.13 ? 135 THR A C 1 ATOM 786 O O . THR A 1 103 ? 32.879 0.314 -19.806 1.00 27.61 ? 135 THR A O 1 ATOM 787 C CB . THR A 1 103 ? 29.755 1.168 -20.432 1.00 28.62 ? 135 THR A CB 1 ATOM 788 O OG1 . THR A 1 103 ? 28.851 1.614 -21.446 1.00 28.96 ? 135 THR A OG1 1 ATOM 789 C CG2 . THR A 1 103 ? 30.444 2.376 -19.818 1.00 28.43 ? 135 THR A CG2 1 ATOM 790 N N . ILE A 1 104 ? 31.270 -1.124 -19.080 1.00 28.87 ? 136 ILE A N 1 ATOM 791 C CA . ILE A 1 104 ? 32.087 -1.718 -18.019 1.00 29.30 ? 136 ILE A CA 1 ATOM 792 C C . ILE A 1 104 ? 33.300 -2.437 -18.604 1.00 28.97 ? 136 ILE A C 1 ATOM 793 O O . ILE A 1 104 ? 34.432 -2.253 -18.142 1.00 26.84 ? 136 ILE A O 1 ATOM 794 C CB . ILE A 1 104 ? 31.273 -2.736 -17.189 1.00 28.99 ? 136 ILE A CB 1 ATOM 795 C CG1 . ILE A 1 104 ? 30.231 -2.006 -16.338 1.00 28.56 ? 136 ILE A CG1 1 ATOM 796 C CG2 . ILE A 1 104 ? 32.189 -3.593 -16.314 1.00 29.03 ? 136 ILE A CG2 1 ATOM 797 C CD1 . ILE A 1 104 ? 29.080 -2.903 -15.908 1.00 28.57 ? 136 ILE A CD1 1 ATOM 798 N N . GLN A 1 105 ? 33.046 -3.272 -19.610 1.00 29.23 ? 137 GLN A N 1 ATOM 799 C CA . GLN A 1 105 ? 34.099 -4.096 -20.180 1.00 30.01 ? 137 GLN A CA 1 ATOM 800 C C . GLN A 1 105 ? 35.179 -3.233 -20.806 1.00 31.20 ? 137 GLN A C 1 ATOM 801 O O . GLN A 1 105 ? 36.342 -3.548 -20.685 1.00 33.25 ? 137 GLN A O 1 ATOM 802 C CB . GLN A 1 105 ? 33.545 -5.118 -21.175 1.00 28.93 ? 137 GLN A CB 1 ATOM 803 C CG . GLN A 1 105 ? 32.913 -6.319 -20.497 1.00 29.03 ? 137 GLN A CG 1 ATOM 804 C CD . GLN A 1 105 ? 32.258 -7.293 -21.469 1.00 31.05 ? 137 GLN A CD 1 ATOM 805 O OE1 . GLN A 1 105 ? 32.466 -7.217 -22.682 1.00 33.06 ? 137 GLN A OE1 1 ATOM 806 N NE2 . GLN A 1 105 ? 31.454 -8.219 -20.938 1.00 31.45 ? 137 GLN A NE2 1 ATOM 807 N N . SER A 1 106 ? 34.801 -2.133 -21.439 1.00 33.26 ? 138 SER A N 1 ATOM 808 C CA . SER A 1 106 ? 35.777 -1.194 -22.001 1.00 35.46 ? 138 SER A CA 1 ATOM 809 C C . SER A 1 106 ? 36.657 -0.567 -20.948 1.00 34.67 ? 138 SER A C 1 ATOM 810 O O . SER A 1 106 ? 37.873 -0.554 -21.101 1.00 36.26 ? 138 SER A O 1 ATOM 811 C CB . SER A 1 106 ? 35.073 -0.067 -22.748 1.00 38.17 ? 138 SER A CB 1 ATOM 812 O OG . SER A 1 106 ? 34.049 -0.606 -23.572 1.00 44.83 ? 138 SER A OG 1 ATOM 813 N N . LEU A 1 107 ? 36.039 -0.026 -19.900 1.00 33.66 ? 139 LEU A N 1 ATOM 814 C CA . LEU A 1 107 ? 36.777 0.645 -18.837 1.00 31.47 ? 139 LEU A CA 1 ATOM 815 C C . LEU A 1 107 ? 37.499 -0.333 -17.944 1.00 30.13 ? 139 LEU A C 1 ATOM 816 O O . LEU A 1 107 ? 38.497 0.025 -17.358 1.00 30.54 ? 139 LEU A O 1 ATOM 817 C CB . LEU A 1 107 ? 35.842 1.468 -17.976 1.00 32.34 ? 139 LEU A CB 1 ATOM 818 C CG . LEU A 1 107 ? 35.273 2.726 -18.619 1.00 34.42 ? 139 LEU A CG 1 ATOM 819 C CD1 . LEU A 1 107 ? 33.985 3.120 -17.926 1.00 35.15 ? 139 LEU A CD1 1 ATOM 820 C CD2 . LEU A 1 107 ? 36.259 3.882 -18.556 1.00 35.68 ? 139 LEU A CD2 1 ATOM 821 N N . PHE A 1 108 ? 36.985 -1.551 -17.826 1.00 29.35 ? 140 PHE A N 1 ATOM 822 C CA . PHE A 1 108 ? 37.527 -2.531 -16.889 1.00 30.79 ? 140 PHE A CA 1 ATOM 823 C C . PHE A 1 108 ? 37.812 -3.838 -17.631 1.00 33.44 ? 140 PHE A C 1 ATOM 824 O O . PHE A 1 108 ? 37.230 -4.907 -17.338 1.00 31.06 ? 140 PHE A O 1 ATOM 825 C CB . PHE A 1 108 ? 36.600 -2.731 -15.664 1.00 30.33 ? 140 PHE A CB 1 ATOM 826 C CG . PHE A 1 108 ? 36.317 -1.451 -14.893 1.00 29.00 ? 140 PHE A CG 1 ATOM 827 C CD1 . PHE A 1 108 ? 37.333 -0.769 -14.243 1.00 27.95 ? 140 PHE A CD1 1 ATOM 828 C CD2 . PHE A 1 108 ? 35.042 -0.923 -14.834 1.00 28.39 ? 140 PHE A CD2 1 ATOM 829 C CE1 . PHE A 1 108 ? 37.083 0.418 -13.563 1.00 27.39 ? 140 PHE A CE1 1 ATOM 830 C CE2 . PHE A 1 108 ? 34.793 0.252 -14.143 1.00 27.93 ? 140 PHE A CE2 1 ATOM 831 C CZ . PHE A 1 108 ? 35.811 0.927 -13.510 1.00 26.87 ? 140 PHE A CZ 1 ATOM 832 N N . PRO A 1 109 ? 38.746 -3.756 -18.595 1.00 37.88 ? 141 PRO A N 1 ATOM 833 C CA . PRO A 1 109 ? 39.116 -4.881 -19.480 1.00 39.67 ? 141 PRO A CA 1 ATOM 834 C C . PRO A 1 109 ? 39.608 -6.116 -18.733 1.00 42.49 ? 141 PRO A C 1 ATOM 835 O O . PRO A 1 109 ? 39.272 -7.248 -19.111 1.00 41.82 ? 141 PRO A O 1 ATOM 836 C CB . PRO A 1 109 ? 40.246 -4.298 -20.334 1.00 39.29 ? 141 PRO A CB 1 ATOM 837 C CG . PRO A 1 109 ? 40.769 -3.113 -19.572 1.00 38.87 ? 141 PRO A CG 1 ATOM 838 C CD . PRO A 1 109 ? 39.595 -2.564 -18.827 1.00 37.89 ? 141 PRO A CD 1 ATOM 839 N N . ASN A 1 110 ? 40.389 -5.881 -17.678 1.00 45.77 ? 142 ASN A N 1 ATOM 840 C CA . ASN A 1 110 ? 40.967 -6.956 -16.876 1.00 48.11 ? 142 ASN A CA 1 ATOM 841 C C . ASN A 1 110 ? 40.144 -7.369 -15.662 1.00 42.83 ? 142 ASN A C 1 ATOM 842 O O . ASN A 1 110 ? 40.457 -8.364 -15.008 1.00 41.58 ? 142 ASN A O 1 ATOM 843 C CB . ASN A 1 110 ? 42.354 -6.544 -16.410 1.00 53.76 ? 142 ASN A CB 1 ATOM 844 C CG . ASN A 1 110 ? 43.281 -6.256 -17.563 1.00 58.36 ? 142 ASN A CG 1 ATOM 845 O OD1 . ASN A 1 110 ? 43.788 -5.140 -17.707 1.00 66.07 ? 142 ASN A OD1 1 ATOM 846 N ND2 . ASN A 1 110 ? 43.491 -7.257 -18.414 1.00 59.36 ? 142 ASN A ND2 1 ATOM 847 N N . LEU A 1 111 ? 39.097 -6.616 -15.361 1.00 38.62 ? 143 LEU A N 1 ATOM 848 C CA . LEU A 1 111 ? 38.307 -6.868 -14.170 1.00 35.35 ? 143 LEU A CA 1 ATOM 849 C C . LEU A 1 111 ? 37.199 -7.896 -14.397 1.00 33.04 ? 143 LEU A C 1 ATOM 850 O O . LEU A 1 111 ? 36.421 -7.782 -15.348 1.00 35.28 ? 143 LEU A O 1 ATOM 851 C CB . LEU A 1 111 ? 37.685 -5.573 -13.696 1.00 35.26 ? 143 LEU A CB 1 ATOM 852 C CG . LEU A 1 111 ? 36.897 -5.685 -12.404 1.00 35.72 ? 143 LEU A CG 1 ATOM 853 C CD1 . LEU A 1 111 ? 37.754 -6.238 -11.282 1.00 36.39 ? 143 LEU A CD1 1 ATOM 854 C CD2 . LEU A 1 111 ? 36.381 -4.304 -12.064 1.00 36.43 ? 143 LEU A CD2 1 ATOM 855 N N . GLN A 1 112 ? 37.130 -8.893 -13.517 1.00 28.72 ? 144 GLN A N 1 ATOM 856 C CA . GLN A 1 112 ? 36.042 -9.846 -13.533 1.00 24.73 ? 144 GLN A CA 1 ATOM 857 C C . GLN A 1 112 ? 34.851 -9.185 -12.839 1.00 23.43 ? 144 GLN A C 1 ATOM 858 O O . GLN A 1 112 ? 35.013 -8.369 -11.921 1.00 22.34 ? 144 GLN A O 1 ATOM 859 C CB . GLN A 1 112 ? 36.434 -11.133 -12.826 1.00 23.50 ? 144 GLN A CB 1 ATOM 860 C CG . GLN A 1 112 ? 35.418 -12.235 -13.023 1.00 23.44 ? 144 GLN A CG 1 ATOM 861 C CD . GLN A 1 112 ? 35.825 -13.586 -12.443 1.00 23.65 ? 144 GLN A CD 1 ATOM 862 O OE1 . GLN A 1 112 ? 36.735 -13.715 -11.603 1.00 23.40 ? 144 GLN A OE1 1 ATOM 863 N NE2 . GLN A 1 112 ? 35.111 -14.608 -12.866 1.00 23.44 ? 144 GLN A NE2 1 ATOM 864 N N . VAL A 1 113 ? 33.663 -9.532 -13.314 1.00 21.28 ? 145 VAL A N 1 ATOM 865 C CA . VAL A 1 113 ? 32.429 -8.964 -12.851 1.00 19.84 ? 145 VAL A CA 1 ATOM 866 C C . VAL A 1 113 ? 31.426 -10.084 -12.799 1.00 19.98 ? 145 VAL A C 1 ATOM 867 O O . VAL A 1 113 ? 31.382 -10.920 -13.679 1.00 19.32 ? 145 VAL A O 1 ATOM 868 C CB . VAL A 1 113 ? 31.896 -7.927 -13.843 1.00 19.47 ? 145 VAL A CB 1 ATOM 869 C CG1 . VAL A 1 113 ? 30.687 -7.212 -13.270 1.00 19.68 ? 145 VAL A CG1 1 ATOM 870 C CG2 . VAL A 1 113 ? 32.973 -6.931 -14.218 1.00 19.24 ? 145 VAL A CG2 1 ATOM 871 N N . PHE A 1 114 ? 30.595 -10.091 -11.778 1.00 21.29 ? 146 PHE A N 1 ATOM 872 C CA . PHE A 1 114 ? 29.572 -11.116 -11.658 1.00 22.46 ? 146 PHE A CA 1 ATOM 873 C C . PHE A 1 114 ? 28.206 -10.452 -11.609 1.00 22.50 ? 146 PHE A C 1 ATOM 874 O O . PHE A 1 114 ? 27.813 -9.900 -10.576 1.00 23.65 ? 146 PHE A O 1 ATOM 875 C CB . PHE A 1 114 ? 29.772 -11.924 -10.396 1.00 23.20 ? 146 PHE A CB 1 ATOM 876 C CG . PHE A 1 114 ? 31.142 -12.475 -10.249 1.00 24.01 ? 146 PHE A CG 1 ATOM 877 C CD1 . PHE A 1 114 ? 32.199 -11.644 -9.922 1.00 24.24 ? 146 PHE A CD1 1 ATOM 878 C CD2 . PHE A 1 114 ? 31.366 -13.838 -10.402 1.00 24.60 ? 146 PHE A CD2 1 ATOM 879 C CE1 . PHE A 1 114 ? 33.463 -12.165 -9.764 1.00 25.29 ? 146 PHE A CE1 1 ATOM 880 C CE2 . PHE A 1 114 ? 32.624 -14.363 -10.246 1.00 24.80 ? 146 PHE A CE2 1 ATOM 881 C CZ . PHE A 1 114 ? 33.676 -13.526 -9.927 1.00 25.66 ? 146 PHE A CZ 1 ATOM 882 N N . PRO A 1 115 ? 27.488 -10.474 -12.736 1.00 21.12 ? 147 PRO A N 1 ATOM 883 C CA . PRO A 1 115 ? 26.167 -9.904 -12.765 1.00 19.54 ? 147 PRO A CA 1 ATOM 884 C C . PRO A 1 115 ? 25.162 -10.804 -12.155 1.00 18.23 ? 147 PRO A C 1 ATOM 885 O O . PRO A 1 115 ? 25.394 -11.985 -12.040 1.00 18.34 ? 147 PRO A O 1 ATOM 886 C CB . PRO A 1 115 ? 25.871 -9.780 -14.248 1.00 20.07 ? 147 PRO A CB 1 ATOM 887 C CG . PRO A 1 115 ? 27.204 -9.667 -14.874 1.00 20.67 ? 147 PRO A CG 1 ATOM 888 C CD . PRO A 1 115 ? 28.017 -10.653 -14.093 1.00 21.20 ? 147 PRO A CD 1 ATOM 889 N N . ALA A 1 116 ? 24.065 -10.210 -11.727 1.00 17.78 ? 148 ALA A N 1 ATOM 890 C CA . ALA A 1 116 ? 22.856 -10.926 -11.460 1.00 17.42 ? 148 ALA A CA 1 ATOM 891 C C . ALA A 1 116 ? 21.775 -10.168 -12.213 1.00 17.45 ? 148 ALA A C 1 ATOM 892 O O . ALA A 1 116 ? 21.955 -8.979 -12.569 1.00 17.03 ? 148 ALA A O 1 ATOM 893 C CB . ALA A 1 116 ? 22.570 -10.957 -9.978 1.00 17.15 ? 148 ALA A CB 1 ATOM 894 N N . LEU A 1 117 ? 20.671 -10.863 -12.473 1.00 17.27 ? 149 LEU A N 1 ATOM 895 C CA . LEU A 1 117 ? 19.542 -10.251 -13.149 1.00 17.83 ? 149 LEU A CA 1 ATOM 896 C C . LEU A 1 117 ? 18.628 -9.590 -12.146 1.00 18.34 ? 149 LEU A C 1 ATOM 897 O O . LEU A 1 117 ? 18.370 -10.139 -11.070 1.00 19.46 ? 149 LEU A O 1 ATOM 898 C CB . LEU A 1 117 ? 18.755 -11.287 -13.956 1.00 17.55 ? 149 LEU A CB 1 ATOM 899 C CG . LEU A 1 117 ? 19.506 -11.829 -15.162 1.00 17.55 ? 149 LEU A CG 1 ATOM 900 C CD1 . LEU A 1 117 ? 18.681 -12.901 -15.846 1.00 17.63 ? 149 LEU A CD1 1 ATOM 901 C CD2 . LEU A 1 117 ? 19.853 -10.714 -16.133 1.00 17.64 ? 149 LEU A CD2 1 ATOM 902 N N . GLY A 1 118 ? 18.147 -8.410 -12.502 1.00 18.36 ? 150 GLY A N 1 ATOM 903 C CA . GLY A 1 118 ? 17.098 -7.769 -11.744 1.00 18.97 ? 150 GLY A CA 1 ATOM 904 C C . GLY A 1 118 ? 15.788 -7.823 -12.505 1.00 19.28 ? 150 GLY A C 1 ATOM 905 O O . GLY A 1 118 ? 15.719 -8.334 -13.603 1.00 18.69 ? 150 GLY A O 1 ATOM 906 N N . ASN A 1 119 ? 14.750 -7.245 -11.927 1.00 19.93 ? 151 ASN A N 1 ATOM 907 C CA . ASN A 1 119 ? 13.414 -7.453 -12.422 1.00 20.64 ? 151 ASN A CA 1 ATOM 908 C C . ASN A 1 119 ? 13.060 -6.579 -13.602 1.00 20.94 ? 151 ASN A C 1 ATOM 909 O O . ASN A 1 119 ? 12.181 -6.920 -14.371 1.00 22.05 ? 151 ASN A O 1 ATOM 910 C CB . ASN A 1 119 ? 12.385 -7.306 -11.302 1.00 21.49 ? 151 ASN A CB 1 ATOM 911 C CG . ASN A 1 119 ? 12.565 -6.035 -10.494 1.00 22.42 ? 151 ASN A CG 1 ATOM 912 O OD1 . ASN A 1 119 ? 13.573 -5.845 -9.793 1.00 23.46 ? 151 ASN A OD1 1 ATOM 913 N ND2 . ASN A 1 119 ? 11.566 -5.174 -10.544 1.00 22.81 ? 151 ASN A ND2 1 ATOM 914 N N . HIS A 1 120 ? 13.736 -5.463 -13.775 1.00 20.78 ? 152 HIS A N 1 ATOM 915 C CA . HIS A 1 120 ? 13.584 -4.736 -15.020 1.00 20.81 ? 152 HIS A CA 1 ATOM 916 C C . HIS A 1 120 ? 14.526 -5.207 -16.116 1.00 21.12 ? 152 HIS A C 1 ATOM 917 O O . HIS A 1 120 ? 14.538 -4.626 -17.181 1.00 20.16 ? 152 HIS A O 1 ATOM 918 C CB . HIS A 1 120 ? 13.848 -3.275 -14.800 1.00 20.53 ? 152 HIS A CB 1 ATOM 919 C CG . HIS A 1 120 ? 12.829 -2.621 -13.956 1.00 20.58 ? 152 HIS A CG 1 ATOM 920 N ND1 . HIS A 1 120 ? 12.008 -1.632 -14.433 1.00 21.03 ? 152 HIS A ND1 1 ATOM 921 C CD2 . HIS A 1 120 ? 12.509 -2.791 -12.654 1.00 20.80 ? 152 HIS A CD2 1 ATOM 922 C CE1 . HIS A 1 120 ? 11.224 -1.213 -13.453 1.00 21.46 ? 152 HIS A CE1 1 ATOM 923 N NE2 . HIS A 1 120 ? 11.512 -1.897 -12.362 1.00 20.48 ? 152 HIS A NE2 1 ATOM 924 N N . ASP A 1 121 ? 15.359 -6.208 -15.870 1.00 22.24 ? 153 ASP A N 1 ATOM 925 C CA . ASP A 1 121 ? 16.221 -6.700 -16.944 1.00 23.65 ? 153 ASP A CA 1 ATOM 926 C C . ASP A 1 121 ? 15.444 -7.778 -17.736 1.00 25.96 ? 153 ASP A C 1 ATOM 927 O O . ASP A 1 121 ? 15.931 -8.884 -17.974 1.00 25.90 ? 153 ASP A O 1 ATOM 928 C CB . ASP A 1 121 ? 17.541 -7.236 -16.393 1.00 22.89 ? 153 ASP A CB 1 ATOM 929 C CG . ASP A 1 121 ? 18.342 -6.181 -15.647 1.00 22.04 ? 153 ASP A CG 1 ATOM 930 O OD1 . ASP A 1 121 ? 18.455 -5.023 -16.140 1.00 19.80 ? 153 ASP A OD1 1 ATOM 931 O OD2 . ASP A 1 121 ? 18.873 -6.547 -14.566 1.00 21.55 -1 153 ASP A OD2 1 ATOM 932 N N . TYR A 1 122 ? 14.215 -7.417 -18.112 1.00 27.92 ? 154 TYR A N 1 ATOM 933 C CA . TYR A 1 122 ? 13.318 -8.249 -18.888 1.00 27.82 ? 154 TYR A CA 1 ATOM 934 C C . TYR A 1 122 ? 12.213 -7.359 -19.465 1.00 29.54 ? 154 TYR A C 1 ATOM 935 O O . TYR A 1 122 ? 11.946 -6.242 -18.963 1.00 30.66 ? 154 TYR A O 1 ATOM 936 C CB . TYR A 1 122 ? 12.704 -9.338 -18.019 1.00 27.26 ? 154 TYR A CB 1 ATOM 937 C CG . TYR A 1 122 ? 12.361 -10.558 -18.805 1.00 27.91 ? 154 TYR A CG 1 ATOM 938 C CD1 . TYR A 1 122 ? 13.343 -11.497 -19.118 1.00 28.39 ? 154 TYR A CD1 1 ATOM 939 C CD2 . TYR A 1 122 ? 11.067 -10.778 -19.268 1.00 28.11 ? 154 TYR A CD2 1 ATOM 940 C CE1 . TYR A 1 122 ? 13.048 -12.627 -19.864 1.00 28.52 ? 154 TYR A CE1 1 ATOM 941 C CE2 . TYR A 1 122 ? 10.759 -11.916 -20.009 1.00 28.75 ? 154 TYR A CE2 1 ATOM 942 C CZ . TYR A 1 122 ? 11.755 -12.838 -20.317 1.00 28.47 ? 154 TYR A CZ 1 ATOM 943 O OH . TYR A 1 122 ? 11.472 -13.981 -21.054 1.00 26.70 ? 154 TYR A OH 1 ATOM 944 N N . TRP A 1 123 ? 11.595 -7.844 -20.537 1.00 30.08 ? 155 TRP A N 1 ATOM 945 C CA . TRP A 1 123 ? 10.388 -7.234 -21.084 1.00 29.55 ? 155 TRP A CA 1 ATOM 946 C C . TRP A 1 123 ? 9.331 -8.329 -21.287 1.00 30.43 ? 155 TRP A C 1 ATOM 947 O O . TRP A 1 123 ? 9.595 -9.307 -21.968 1.00 31.23 ? 155 TRP A O 1 ATOM 948 C CB . TRP A 1 123 ? 10.667 -6.517 -22.398 1.00 28.50 ? 155 TRP A CB 1 ATOM 949 C CG . TRP A 1 123 ? 9.513 -5.705 -22.796 1.00 29.23 ? 155 TRP A CG 1 ATOM 950 C CD1 . TRP A 1 123 ? 9.325 -4.372 -22.568 1.00 29.25 ? 155 TRP A CD1 1 ATOM 951 C CD2 . TRP A 1 123 ? 8.323 -6.174 -23.440 1.00 30.86 ? 155 TRP A CD2 1 ATOM 952 N NE1 . TRP A 1 123 ? 8.094 -3.977 -23.037 1.00 29.19 ? 155 TRP A NE1 1 ATOM 953 C CE2 . TRP A 1 123 ? 7.462 -5.063 -23.585 1.00 30.07 ? 155 TRP A CE2 1 ATOM 954 C CE3 . TRP A 1 123 ? 7.902 -7.429 -23.924 1.00 29.71 ? 155 TRP A CE3 1 ATOM 955 C CZ2 . TRP A 1 123 ? 6.220 -5.165 -24.203 1.00 29.71 ? 155 TRP A CZ2 1 ATOM 956 C CZ3 . TRP A 1 123 ? 6.669 -7.525 -24.525 1.00 28.50 ? 155 TRP A CZ3 1 ATOM 957 C CH2 . TRP A 1 123 ? 5.844 -6.402 -24.668 1.00 29.24 ? 155 TRP A CH2 1 ATOM 958 N N . PRO A 1 124 ? 8.145 -8.190 -20.699 1.00 30.61 ? 156 PRO A N 1 ATOM 959 C CA . PRO A 1 124 ? 7.775 -7.067 -19.798 1.00 31.13 ? 156 PRO A CA 1 ATOM 960 C C . PRO A 1 124 ? 8.417 -7.191 -18.409 1.00 29.48 ? 156 PRO A C 1 ATOM 961 O O . PRO A 1 124 ? 8.709 -8.301 -17.958 1.00 29.91 ? 156 PRO A O 1 ATOM 962 C CB . PRO A 1 124 ? 6.246 -7.175 -19.699 1.00 30.80 ? 156 PRO A CB 1 ATOM 963 C CG . PRO A 1 124 ? 5.925 -8.569 -20.126 1.00 30.35 ? 156 PRO A CG 1 ATOM 964 C CD . PRO A 1 124 ? 7.040 -9.122 -20.953 1.00 29.39 ? 156 PRO A CD 1 ATOM 965 N N . GLN A 1 125 ? 8.637 -6.077 -17.732 1.00 26.50 ? 157 GLN A N 1 ATOM 966 C CA . GLN A 1 125 ? 9.287 -6.165 -16.445 1.00 26.01 ? 157 GLN A CA 1 ATOM 967 C C . GLN A 1 125 ? 8.700 -7.242 -15.545 1.00 25.05 ? 157 GLN A C 1 ATOM 968 O O . GLN A 1 125 ? 7.552 -7.596 -15.675 1.00 22.95 ? 157 GLN A O 1 ATOM 969 C CB . GLN A 1 125 ? 9.298 -4.813 -15.731 1.00 26.82 ? 157 GLN A CB 1 ATOM 970 C CG . GLN A 1 125 ? 7.962 -4.187 -15.371 1.00 26.69 ? 157 GLN A CG 1 ATOM 971 C CD . GLN A 1 125 ? 8.152 -2.735 -14.965 1.00 27.13 ? 157 GLN A CD 1 ATOM 972 O OE1 . GLN A 1 125 ? 8.305 -1.839 -15.815 1.00 28.75 ? 157 GLN A OE1 1 ATOM 973 N NE2 . GLN A 1 125 ? 8.196 -2.495 -13.665 1.00 27.05 ? 157 GLN A NE2 1 ATOM 974 N N . ASP A 1 126 ? 9.549 -7.795 -14.683 1.00 26.65 ? 158 ASP A N 1 ATOM 975 C CA . ASP A 1 126 ? 9.177 -8.758 -13.629 1.00 29.01 ? 158 ASP A CA 1 ATOM 976 C C . ASP A 1 126 ? 8.824 -10.185 -14.075 1.00 28.08 ? 158 ASP A C 1 ATOM 977 O O . ASP A 1 126 ? 8.688 -11.090 -13.254 1.00 25.74 ? 158 ASP A O 1 ATOM 978 C CB . ASP A 1 126 ? 8.024 -8.214 -12.778 1.00 32.43 ? 158 ASP A CB 1 ATOM 979 C CG . ASP A 1 126 ? 8.223 -6.775 -12.365 1.00 34.55 ? 158 ASP A CG 1 ATOM 980 O OD1 . ASP A 1 126 ? 9.328 -6.253 -12.596 1.00 34.86 ? 158 ASP A OD1 1 ATOM 981 O OD2 . ASP A 1 126 ? 7.263 -6.176 -11.822 1.00 38.09 -1 158 ASP A OD2 1 ATOM 982 N N . GLN A 1 127 ? 8.707 -10.400 -15.368 1.00 29.01 ? 159 GLN A N 1 ATOM 983 C CA . GLN A 1 127 ? 8.160 -11.637 -15.869 1.00 30.65 ? 159 GLN A CA 1 ATOM 984 C C . GLN A 1 127 ? 9.290 -12.557 -16.272 1.00 32.34 ? 159 GLN A C 1 ATOM 985 O O . GLN A 1 127 ? 9.290 -13.129 -17.356 1.00 35.81 ? 159 GLN A O 1 ATOM 986 C CB . GLN A 1 127 ? 7.248 -11.324 -17.047 1.00 30.24 ? 159 GLN A CB 1 ATOM 987 C CG . GLN A 1 127 ? 6.241 -10.236 -16.719 1.00 30.29 ? 159 GLN A CG 1 ATOM 988 C CD . GLN A 1 127 ? 5.365 -10.615 -15.537 1.00 30.24 ? 159 GLN A CD 1 ATOM 989 O OE1 . GLN A 1 127 ? 4.773 -11.690 -15.537 1.00 32.72 ? 159 GLN A OE1 1 ATOM 990 N NE2 . GLN A 1 127 ? 5.281 -9.749 -14.530 1.00 28.47 ? 159 GLN A NE2 1 ATOM 991 N N . LEU A 1 128 ? 10.267 -12.694 -15.394 1.00 32.89 ? 160 LEU A N 1 ATOM 992 C CA . LEU A 1 128 ? 11.422 -13.503 -15.707 1.00 33.31 ? 160 LEU A CA 1 ATOM 993 C C . LEU A 1 128 ? 10.949 -14.956 -15.649 1.00 34.44 ? 160 LEU A C 1 ATOM 994 O O . LEU A 1 128 ? 10.295 -15.334 -14.683 1.00 35.39 ? 160 LEU A O 1 ATOM 995 C CB . LEU A 1 128 ? 12.568 -13.191 -14.738 1.00 32.24 ? 160 LEU A CB 1 ATOM 996 C CG . LEU A 1 128 ? 13.323 -11.887 -15.089 1.00 31.57 ? 160 LEU A CG 1 ATOM 997 C CD1 . LEU A 1 128 ? 12.566 -10.629 -14.683 1.00 30.89 ? 160 LEU A CD1 1 ATOM 998 C CD2 . LEU A 1 128 ? 14.711 -11.886 -14.472 1.00 31.47 ? 160 LEU A CD2 1 ATOM 999 N N . PRO A 1 129 ? 11.204 -15.747 -16.716 1.00 35.01 ? 161 PRO A N 1 ATOM 1000 C CA . PRO A 1 129 ? 10.699 -17.121 -16.809 1.00 34.57 ? 161 PRO A CA 1 ATOM 1001 C C . PRO A 1 129 ? 11.607 -18.225 -16.260 1.00 33.14 ? 161 PRO A C 1 ATOM 1002 O O . PRO A 1 129 ? 12.759 -17.977 -15.879 1.00 31.54 ? 161 PRO A O 1 ATOM 1003 C CB . PRO A 1 129 ? 10.536 -17.313 -18.317 1.00 34.56 ? 161 PRO A CB 1 ATOM 1004 C CG . PRO A 1 129 ? 11.672 -16.542 -18.876 1.00 34.73 ? 161 PRO A CG 1 ATOM 1005 C CD . PRO A 1 129 ? 11.701 -15.290 -18.030 1.00 35.11 ? 161 PRO A CD 1 ATOM 1006 N N . VAL A 1 130 ? 11.036 -19.432 -16.270 1.00 32.48 ? 162 VAL A N 1 ATOM 1007 C CA . VAL A 1 130 ? 11.602 -20.679 -15.728 1.00 32.21 ? 162 VAL A CA 1 ATOM 1008 C C . VAL A 1 130 ? 12.522 -21.384 -16.723 1.00 31.21 ? 162 VAL A C 1 ATOM 1009 O O . VAL A 1 130 ? 13.447 -22.128 -16.369 1.00 30.74 ? 162 VAL A O 1 ATOM 1010 C CB . VAL A 1 130 ? 10.440 -21.661 -15.441 1.00 33.52 ? 162 VAL A CB 1 ATOM 1011 C CG1 . VAL A 1 130 ? 10.934 -23.093 -15.156 1.00 33.62 ? 162 VAL A CG1 1 ATOM 1012 C CG2 . VAL A 1 130 ? 9.535 -21.110 -14.336 1.00 33.90 ? 162 VAL A CG2 1 ATOM 1013 N N . VAL A 1 131 ? 12.227 -21.164 -17.986 1.00 30.58 ? 163 VAL A N 1 ATOM 1014 C CA . VAL A 1 131 ? 12.877 -21.874 -19.056 1.00 30.83 ? 163 VAL A CA 1 ATOM 1015 C C . VAL A 1 131 ? 13.615 -20.838 -19.867 1.00 31.61 ? 163 VAL A C 1 ATOM 1016 O O . VAL A 1 131 ? 13.334 -19.635 -19.747 1.00 35.89 ? 163 VAL A O 1 ATOM 1017 C CB . VAL A 1 131 ? 11.833 -22.582 -19.936 1.00 30.43 ? 163 VAL A CB 1 ATOM 1018 C CG1 . VAL A 1 131 ? 10.881 -23.413 -19.073 1.00 29.41 ? 163 VAL A CG1 1 ATOM 1019 C CG2 . VAL A 1 131 ? 11.058 -21.568 -20.781 1.00 30.73 ? 163 VAL A CG2 1 ATOM 1020 N N . THR A 1 132 ? 14.538 -21.287 -20.704 1.00 29.82 ? 164 THR A N 1 ATOM 1021 C CA . THR A 1 132 ? 15.315 -20.360 -21.519 1.00 28.68 ? 164 THR A CA 1 ATOM 1022 C C . THR A 1 132 ? 14.447 -19.322 -22.301 1.00 27.93 ? 164 THR A C 1 ATOM 1023 O O . THR A 1 132 ? 13.196 -19.442 -22.378 1.00 26.86 ? 164 THR A O 1 ATOM 1024 C CB . THR A 1 132 ? 16.257 -21.126 -22.461 1.00 28.00 ? 164 THR A CB 1 ATOM 1025 O OG1 . THR A 1 132 ? 17.129 -20.194 -23.122 1.00 25.77 ? 164 THR A OG1 1 ATOM 1026 C CG2 . THR A 1 132 ? 15.437 -21.961 -23.481 1.00 28.23 ? 164 THR A CG2 1 ATOM 1027 N N . SER A 1 133 ? 15.127 -18.314 -22.860 1.00 26.39 ? 165 SER A N 1 ATOM 1028 C CA . SER A 1 133 ? 14.472 -17.116 -23.375 1.00 26.69 ? 165 SER A CA 1 ATOM 1029 C C . SER A 1 133 ? 15.457 -16.204 -24.069 1.00 26.93 ? 165 SER A C 1 ATOM 1030 O O . SER A 1 133 ? 16.654 -16.247 -23.820 1.00 26.36 ? 165 SER A O 1 ATOM 1031 C CB . SER A 1 133 ? 13.835 -16.308 -22.234 1.00 27.45 ? 165 SER A CB 1 ATOM 1032 O OG . SER A 1 133 ? 14.823 -15.510 -21.577 1.00 27.69 ? 165 SER A OG 1 ATOM 1033 N N . LYS A 1 134 ? 14.925 -15.313 -24.888 1.00 29.33 ? 166 LYS A N 1 ATOM 1034 C CA . LYS A 1 134 ? 15.747 -14.405 -25.670 1.00 30.69 ? 166 LYS A CA 1 ATOM 1035 C C . LYS A 1 134 ? 16.688 -13.583 -24.790 1.00 30.56 ? 166 LYS A C 1 ATOM 1036 O O . LYS A 1 134 ? 17.847 -13.404 -25.131 1.00 31.08 ? 166 LYS A O 1 ATOM 1037 C CB . LYS A 1 134 ? 14.863 -13.499 -26.530 1.00 32.12 ? 166 LYS A CB 1 ATOM 1038 C CG . LYS A 1 134 ? 15.653 -12.505 -27.359 1.00 35.41 ? 166 LYS A CG 1 ATOM 1039 C CD . LYS A 1 134 ? 14.800 -11.759 -28.377 1.00 38.20 ? 166 LYS A CD 1 ATOM 1040 C CE . LYS A 1 134 ? 15.274 -12.005 -29.797 1.00 41.06 ? 166 LYS A CE 1 ATOM 1041 N NZ . LYS A 1 134 ? 14.581 -11.073 -30.727 1.00 43.50 1 166 LYS A NZ 1 ATOM 1042 N N . VAL A 1 135 ? 16.197 -13.109 -23.651 1.00 31.13 ? 167 VAL A N 1 ATOM 1043 C CA . VAL A 1 135 ? 16.999 -12.271 -22.740 1.00 30.63 ? 167 VAL A CA 1 ATOM 1044 C C . VAL A 1 135 ? 18.070 -13.094 -22.014 1.00 29.22 ? 167 VAL A C 1 ATOM 1045 O O . VAL A 1 135 ? 19.248 -12.699 -21.941 1.00 27.47 ? 167 VAL A O 1 ATOM 1046 C CB . VAL A 1 135 ? 16.106 -11.584 -21.684 1.00 30.97 ? 167 VAL A CB 1 ATOM 1047 C CG1 . VAL A 1 135 ? 16.939 -10.744 -20.733 1.00 30.79 ? 167 VAL A CG1 1 ATOM 1048 C CG2 . VAL A 1 135 ? 15.057 -10.724 -22.369 1.00 31.83 ? 167 VAL A CG2 1 ATOM 1049 N N . TYR A 1 136 ? 17.659 -14.237 -21.480 1.00 27.72 ? 168 TYR A N 1 ATOM 1050 C CA . TYR A 1 136 ? 18.596 -15.105 -20.796 1.00 27.69 ? 168 TYR A CA 1 ATOM 1051 C C . TYR A 1 136 ? 19.763 -15.450 -21.728 1.00 27.97 ? 168 TYR A C 1 ATOM 1052 O O . TYR A 1 136 ? 20.924 -15.484 -21.305 1.00 26.34 ? 168 TYR A O 1 ATOM 1053 C CB . TYR A 1 136 ? 17.898 -16.373 -20.295 1.00 27.57 ? 168 TYR A CB 1 ATOM 1054 C CG . TYR A 1 136 ? 16.919 -16.208 -19.122 1.00 27.95 ? 168 TYR A CG 1 ATOM 1055 C CD1 . TYR A 1 136 ? 16.799 -15.004 -18.383 1.00 27.98 ? 168 TYR A CD1 1 ATOM 1056 C CD2 . TYR A 1 136 ? 16.140 -17.286 -18.713 1.00 28.04 ? 168 TYR A CD2 1 ATOM 1057 C CE1 . TYR A 1 136 ? 15.905 -14.894 -17.305 1.00 26.64 ? 168 TYR A CE1 1 ATOM 1058 C CE2 . TYR A 1 136 ? 15.254 -17.183 -17.641 1.00 27.90 ? 168 TYR A CE2 1 ATOM 1059 C CZ . TYR A 1 136 ? 15.138 -15.998 -16.935 1.00 26.78 ? 168 TYR A CZ 1 ATOM 1060 O OH . TYR A 1 136 ? 14.232 -15.956 -15.893 1.00 24.60 ? 168 TYR A OH 1 ATOM 1061 N N . ASN A 1 137 ? 19.456 -15.673 -23.004 1.00 28.98 ? 169 ASN A N 1 ATOM 1062 C CA . ASN A 1 137 ? 20.491 -16.074 -23.956 1.00 30.85 ? 169 ASN A CA 1 ATOM 1063 C C . ASN A 1 137 ? 21.318 -14.910 -24.404 1.00 31.63 ? 169 ASN A C 1 ATOM 1064 O O . ASN A 1 137 ? 22.493 -15.081 -24.756 1.00 32.18 ? 169 ASN A O 1 ATOM 1065 C CB . ASN A 1 137 ? 19.892 -16.764 -25.164 1.00 31.24 ? 169 ASN A CB 1 ATOM 1066 C CG . ASN A 1 137 ? 19.484 -18.181 -24.858 1.00 33.00 ? 169 ASN A CG 1 ATOM 1067 O OD1 . ASN A 1 137 ? 18.305 -18.469 -24.683 1.00 37.29 ? 169 ASN A OD1 1 ATOM 1068 N ND2 . ASN A 1 137 ? 20.457 -19.073 -24.754 1.00 33.10 ? 169 ASN A ND2 1 ATOM 1069 N N . ALA A 1 138 ? 20.687 -13.738 -24.407 1.00 31.48 ? 170 ALA A N 1 ATOM 1070 C CA . ALA A 1 138 ? 21.342 -12.496 -24.780 1.00 32.14 ? 170 ALA A CA 1 ATOM 1071 C C . ALA A 1 138 ? 22.435 -12.183 -23.766 1.00 35.08 ? 170 ALA A C 1 ATOM 1072 O O . ALA A 1 138 ? 23.592 -11.890 -24.125 1.00 34.45 ? 170 ALA A O 1 ATOM 1073 C CB . ALA A 1 138 ? 20.327 -11.355 -24.851 1.00 30.97 ? 170 ALA A CB 1 ATOM 1074 N N . VAL A 1 139 ? 22.069 -12.261 -22.489 1.00 36.57 ? 171 VAL A N 1 ATOM 1075 C CA . VAL A 1 139 ? 23.026 -11.951 -21.439 1.00 36.42 ? 171 VAL A CA 1 ATOM 1076 C C . VAL A 1 139 ? 24.112 -13.001 -21.377 1.00 36.73 ? 171 VAL A C 1 ATOM 1077 O O . VAL A 1 139 ? 25.265 -12.666 -21.134 1.00 37.82 ? 171 VAL A O 1 ATOM 1078 C CB . VAL A 1 139 ? 22.379 -11.781 -20.054 1.00 35.39 ? 171 VAL A CB 1 ATOM 1079 C CG1 . VAL A 1 139 ? 21.462 -10.575 -20.051 1.00 34.61 ? 171 VAL A CG1 1 ATOM 1080 C CG2 . VAL A 1 139 ? 21.636 -13.030 -19.629 1.00 36.03 ? 171 VAL A CG2 1 ATOM 1081 N N . ALA A 1 140 ? 23.772 -14.264 -21.611 1.00 37.02 ? 172 ALA A N 1 ATOM 1082 C CA . ALA A 1 140 ? 24.807 -15.291 -21.590 1.00 39.35 ? 172 ALA A CA 1 ATOM 1083 C C . ALA A 1 140 ? 25.919 -14.945 -22.606 1.00 40.41 ? 172 ALA A C 1 ATOM 1084 O O . ALA A 1 140 ? 27.111 -15.059 -22.295 1.00 40.40 ? 172 ALA A O 1 ATOM 1085 C CB . ALA A 1 140 ? 24.223 -16.678 -21.830 1.00 39.09 ? 172 ALA A CB 1 ATOM 1086 N N . ASN A 1 141 ? 25.540 -14.464 -23.785 1.00 40.13 ? 173 ASN A N 1 ATOM 1087 C CA . ASN A 1 141 ? 26.549 -14.048 -24.759 1.00 44.54 ? 173 ASN A CA 1 ATOM 1088 C C . ASN A 1 141 ? 27.359 -12.868 -24.246 1.00 42.25 ? 173 ASN A C 1 ATOM 1089 O O . ASN A 1 141 ? 28.573 -12.893 -24.279 1.00 43.93 ? 173 ASN A O 1 ATOM 1090 C CB . ASN A 1 141 ? 25.925 -13.686 -26.113 1.00 49.62 ? 173 ASN A CB 1 ATOM 1091 C CG . ASN A 1 141 ? 25.148 -14.846 -26.740 1.00 53.68 ? 173 ASN A CG 1 ATOM 1092 O OD1 . ASN A 1 141 ? 25.449 -16.028 -26.503 1.00 53.55 ? 173 ASN A OD1 1 ATOM 1093 N ND2 . ASN A 1 141 ? 24.135 -14.508 -27.549 1.00 54.65 ? 173 ASN A ND2 1 ATOM 1094 N N . LEU A 1 142 ? 26.669 -11.843 -23.761 1.00 40.31 ? 174 LEU A N 1 ATOM 1095 C CA . LEU A 1 142 ? 27.299 -10.623 -23.251 1.00 36.19 ? 174 LEU A CA 1 ATOM 1096 C C . LEU A 1 142 ? 28.248 -10.850 -22.080 1.00 33.89 ? 174 LEU A C 1 ATOM 1097 O O . LEU A 1 142 ? 29.187 -10.079 -21.887 1.00 31.08 ? 174 LEU A O 1 ATOM 1098 C CB . LEU A 1 142 ? 26.214 -9.682 -22.774 1.00 37.13 ? 174 LEU A CB 1 ATOM 1099 C CG . LEU A 1 142 ? 25.302 -9.118 -23.854 1.00 37.89 ? 174 LEU A CG 1 ATOM 1100 C CD1 . LEU A 1 142 ? 23.936 -8.763 -23.284 1.00 37.28 ? 174 LEU A CD1 1 ATOM 1101 C CD2 . LEU A 1 142 ? 25.955 -7.892 -24.476 1.00 38.06 ? 174 LEU A CD2 1 ATOM 1102 N N . TRP A 1 143 ? 27.980 -11.883 -21.282 1.00 33.15 ? 175 TRP A N 1 ATOM 1103 C CA . TRP A 1 143 ? 28.741 -12.118 -20.053 1.00 33.70 ? 175 TRP A CA 1 ATOM 1104 C C . TRP A 1 143 ? 29.670 -13.310 -20.126 1.00 36.04 ? 175 TRP A C 1 ATOM 1105 O O . TRP A 1 143 ? 30.349 -13.605 -19.152 1.00 38.02 ? 175 TRP A O 1 ATOM 1106 C CB . TRP A 1 143 ? 27.808 -12.232 -18.834 1.00 31.12 ? 175 TRP A CB 1 ATOM 1107 C CG . TRP A 1 143 ? 27.007 -10.995 -18.621 1.00 28.85 ? 175 TRP A CG 1 ATOM 1108 C CD1 . TRP A 1 143 ? 27.295 -9.738 -19.083 1.00 28.92 ? 175 TRP A CD1 1 ATOM 1109 C CD2 . TRP A 1 143 ? 25.791 -10.883 -17.899 1.00 27.20 ? 175 TRP A CD2 1 ATOM 1110 N NE1 . TRP A 1 143 ? 26.319 -8.853 -18.701 1.00 28.89 ? 175 TRP A NE1 1 ATOM 1111 C CE2 . TRP A 1 143 ? 25.386 -9.533 -17.963 1.00 27.94 ? 175 TRP A CE2 1 ATOM 1112 C CE3 . TRP A 1 143 ? 24.995 -11.790 -17.207 1.00 27.31 ? 175 TRP A CE3 1 ATOM 1113 C CZ2 . TRP A 1 143 ? 24.225 -9.072 -17.347 1.00 27.27 ? 175 TRP A CZ2 1 ATOM 1114 C CZ3 . TRP A 1 143 ? 23.829 -11.331 -16.603 1.00 27.15 ? 175 TRP A CZ3 1 ATOM 1115 C CH2 . TRP A 1 143 ? 23.461 -9.986 -16.673 1.00 26.99 ? 175 TRP A CH2 1 ATOM 1116 N N . LYS A 1 144 ? 29.716 -13.983 -21.274 1.00 39.00 ? 176 LYS A N 1 ATOM 1117 C CA . LYS A 1 144 ? 30.771 -14.959 -21.561 1.00 39.31 ? 176 LYS A CA 1 ATOM 1118 C C . LYS A 1 144 ? 32.137 -14.489 -21.064 1.00 34.30 ? 176 LYS A C 1 ATOM 1119 O O . LYS A 1 144 ? 32.815 -15.227 -20.343 1.00 36.36 ? 176 LYS A O 1 ATOM 1120 C CB . LYS A 1 144 ? 30.881 -15.225 -23.074 1.00 46.65 ? 176 LYS A CB 1 ATOM 1121 C CG . LYS A 1 144 ? 29.990 -16.343 -23.652 1.00 53.05 ? 176 LYS A CG 1 ATOM 1122 C CD . LYS A 1 144 ? 29.994 -16.374 -25.196 1.00 57.68 ? 176 LYS A CD 1 ATOM 1123 C CE . LYS A 1 144 ? 31.399 -16.157 -25.795 1.00 62.28 ? 176 LYS A CE 1 ATOM 1124 N NZ . LYS A 1 144 ? 31.438 -15.910 -27.267 1.00 63.88 1 176 LYS A NZ 1 ATOM 1125 N N . PRO A 1 145 ? 32.548 -13.260 -21.416 1.00 28.74 ? 177 PRO A N 1 ATOM 1126 C CA . PRO A 1 145 ? 33.933 -12.922 -21.123 1.00 28.44 ? 177 PRO A CA 1 ATOM 1127 C C . PRO A 1 145 ? 34.276 -12.912 -19.642 1.00 30.22 ? 177 PRO A C 1 ATOM 1128 O O . PRO A 1 145 ? 35.430 -12.673 -19.301 1.00 32.40 ? 177 PRO A O 1 ATOM 1129 C CB . PRO A 1 145 ? 34.090 -11.503 -21.677 1.00 27.77 ? 177 PRO A CB 1 ATOM 1130 C CG . PRO A 1 145 ? 32.860 -11.212 -22.433 1.00 28.13 ? 177 PRO A CG 1 ATOM 1131 C CD . PRO A 1 145 ? 31.793 -12.095 -21.876 1.00 28.28 ? 177 PRO A CD 1 ATOM 1132 N N . TRP A 1 146 ? 33.276 -13.121 -18.777 1.00 31.85 ? 178 TRP A N 1 ATOM 1133 C CA . TRP A 1 146 ? 33.449 -13.202 -17.317 1.00 30.42 ? 178 TRP A CA 1 ATOM 1134 C C . TRP A 1 146 ? 33.110 -14.563 -16.712 1.00 33.25 ? 178 TRP A C 1 ATOM 1135 O O . TRP A 1 146 ? 33.354 -14.750 -15.543 1.00 35.82 ? 178 TRP A O 1 ATOM 1136 C CB . TRP A 1 146 ? 32.561 -12.171 -16.610 1.00 27.85 ? 178 TRP A CB 1 ATOM 1137 C CG . TRP A 1 146 ? 32.837 -10.747 -16.930 1.00 25.65 ? 178 TRP A CG 1 ATOM 1138 C CD1 . TRP A 1 146 ? 34.047 -10.179 -17.133 1.00 25.80 ? 178 TRP A CD1 1 ATOM 1139 C CD2 . TRP A 1 146 ? 31.874 -9.696 -17.046 1.00 24.31 ? 178 TRP A CD2 1 ATOM 1140 N NE1 . TRP A 1 146 ? 33.910 -8.835 -17.383 1.00 25.40 ? 178 TRP A NE1 1 ATOM 1141 C CE2 . TRP A 1 146 ? 32.582 -8.512 -17.334 1.00 24.87 ? 178 TRP A CE2 1 ATOM 1142 C CE3 . TRP A 1 146 ? 30.482 -9.643 -16.951 1.00 23.47 ? 178 TRP A CE3 1 ATOM 1143 C CZ2 . TRP A 1 146 ? 31.947 -7.278 -17.509 1.00 24.60 ? 178 TRP A CZ2 1 ATOM 1144 C CZ3 . TRP A 1 146 ? 29.850 -8.429 -17.136 1.00 23.48 ? 178 TRP A CZ3 1 ATOM 1145 C CH2 . TRP A 1 146 ? 30.585 -7.256 -17.405 1.00 24.09 ? 178 TRP A CH2 1 ATOM 1146 N N . LEU A 1 147 ? 32.560 -15.514 -17.455 1.00 36.94 ? 179 LEU A N 1 ATOM 1147 C CA . LEU A 1 147 ? 32.066 -16.724 -16.814 1.00 42.78 ? 179 LEU A CA 1 ATOM 1148 C C . LEU A 1 147 ? 32.486 -18.047 -17.476 1.00 47.62 ? 179 LEU A C 1 ATOM 1149 O O . LEU A 1 147 ? 32.961 -18.076 -18.610 1.00 51.25 ? 179 LEU A O 1 ATOM 1150 C CB . LEU A 1 147 ? 30.537 -16.644 -16.719 1.00 45.35 ? 179 LEU A CB 1 ATOM 1151 C CG . LEU A 1 147 ? 29.899 -15.372 -16.101 1.00 47.90 ? 179 LEU A CG 1 ATOM 1152 C CD1 . LEU A 1 147 ? 28.375 -15.504 -16.090 1.00 49.20 ? 179 LEU A CD1 1 ATOM 1153 C CD2 . LEU A 1 147 ? 30.369 -15.046 -14.684 1.00 46.77 ? 179 LEU A CD2 1 ATOM 1154 N N . ASP A 1 148 ? 32.304 -19.133 -16.722 1.00 50.61 ? 180 ASP A N 1 ATOM 1155 C CA . ASP A 1 148 ? 32.458 -20.519 -17.186 1.00 51.71 ? 180 ASP A CA 1 ATOM 1156 C C . ASP A 1 148 ? 31.495 -20.863 -18.278 1.00 54.14 ? 180 ASP A C 1 ATOM 1157 O O . ASP A 1 148 ? 30.505 -20.183 -18.442 1.00 56.64 ? 180 ASP A O 1 ATOM 1158 C CB . ASP A 1 148 ? 32.049 -21.480 -16.073 1.00 52.75 ? 180 ASP A CB 1 ATOM 1159 C CG . ASP A 1 148 ? 33.112 -21.723 -15.066 1.00 53.60 ? 180 ASP A CG 1 ATOM 1160 O OD1 . ASP A 1 148 ? 34.305 -21.456 -15.326 1.00 52.31 ? 180 ASP A OD1 1 ATOM 1161 O OD2 . ASP A 1 148 ? 32.719 -22.213 -13.990 1.00 56.42 -1 180 ASP A OD2 1 ATOM 1162 N N . GLU A 1 149 ? 31.742 -21.979 -18.956 1.00 57.68 ? 181 GLU A N 1 ATOM 1163 C CA . GLU A 1 149 ? 30.714 -22.614 -19.783 1.00 60.39 ? 181 GLU A CA 1 ATOM 1164 C C . GLU A 1 149 ? 29.632 -23.212 -18.872 1.00 58.78 ? 181 GLU A C 1 ATOM 1165 O O . GLU A 1 149 ? 28.471 -23.330 -19.266 1.00 59.77 ? 181 GLU A O 1 ATOM 1166 C CB . GLU A 1 149 ? 31.281 -23.765 -20.617 1.00 65.89 ? 181 GLU A CB 1 ATOM 1167 C CG . GLU A 1 149 ? 32.523 -23.479 -21.457 1.00 70.65 ? 181 GLU A CG 1 ATOM 1168 C CD . GLU A 1 149 ? 33.311 -24.751 -21.793 1.00 74.60 ? 181 GLU A CD 1 ATOM 1169 O OE1 . GLU A 1 149 ? 32.883 -25.875 -21.417 1.00 72.73 ? 181 GLU A OE1 1 ATOM 1170 O OE2 . GLU A 1 149 ? 34.375 -24.625 -22.436 1.00 73.80 -1 181 GLU A OE2 1 ATOM 1171 N N . GLU A 1 150 ? 30.043 -23.639 -17.680 1.00 54.83 ? 182 GLU A N 1 ATOM 1172 C CA . GLU A 1 150 ? 29.155 -24.273 -16.705 1.00 54.80 ? 182 GLU A CA 1 ATOM 1173 C C . GLU A 1 150 ? 28.185 -23.237 -16.157 1.00 50.65 ? 182 GLU A C 1 ATOM 1174 O O . GLU A 1 150 ? 26.974 -23.477 -16.025 1.00 44.65 ? 182 GLU A O 1 ATOM 1175 C CB . GLU A 1 150 ? 29.970 -24.861 -15.540 1.00 59.19 ? 182 GLU A CB 1 ATOM 1176 C CG . GLU A 1 150 ? 30.939 -25.989 -15.906 1.00 62.96 ? 182 GLU A CG 1 ATOM 1177 C CD . GLU A 1 150 ? 32.242 -25.498 -16.543 1.00 66.15 ? 182 GLU A CD 1 ATOM 1178 O OE1 . GLU A 1 150 ? 33.191 -25.110 -15.820 1.00 62.83 ? 182 GLU A OE1 1 ATOM 1179 O OE2 . GLU A 1 150 ? 32.322 -25.502 -17.789 1.00 71.22 -1 182 GLU A OE2 1 ATOM 1180 N N . ALA A 1 151 ? 28.761 -22.093 -15.807 1.00 45.57 ? 183 ALA A N 1 ATOM 1181 C CA . ALA A 1 151 ? 28.007 -20.935 -15.393 1.00 42.32 ? 183 ALA A CA 1 ATOM 1182 C C . ALA A 1 151 ? 27.041 -20.600 -16.505 1.00 39.36 ? 183 ALA A C 1 ATOM 1183 O O . ALA A 1 151 ? 25.832 -20.805 -16.385 1.00 38.84 ? 183 ALA A O 1 ATOM 1184 C CB . ALA A 1 151 ? 28.951 -19.760 -15.136 1.00 42.65 ? 183 ALA A CB 1 ATOM 1185 N N . ILE A 1 152 ? 27.610 -20.132 -17.609 1.00 37.26 ? 184 ILE A N 1 ATOM 1186 C CA . ILE A 1 152 ? 26.865 -19.704 -18.779 1.00 35.93 ? 184 ILE A CA 1 ATOM 1187 C C . ILE A 1 152 ? 25.731 -20.651 -19.117 1.00 35.18 ? 184 ILE A C 1 ATOM 1188 O O . ILE A 1 152 ? 24.618 -20.232 -19.438 1.00 33.89 ? 184 ILE A O 1 ATOM 1189 C CB . ILE A 1 152 ? 27.814 -19.606 -19.974 1.00 36.58 ? 184 ILE A CB 1 ATOM 1190 C CG1 . ILE A 1 152 ? 28.599 -18.282 -19.902 1.00 39.01 ? 184 ILE A CG1 1 ATOM 1191 C CG2 . ILE A 1 152 ? 27.077 -19.748 -21.297 1.00 38.34 ? 184 ILE A CG2 1 ATOM 1192 C CD1 . ILE A 1 152 ? 27.802 -17.016 -20.177 1.00 39.51 ? 184 ILE A CD1 1 ATOM 1193 N N . SER A 1 153 ? 26.029 -21.935 -19.057 1.00 35.30 ? 185 SER A N 1 ATOM 1194 C CA . SER A 1 153 ? 25.024 -22.935 -19.263 1.00 35.34 ? 185 SER A CA 1 ATOM 1195 C C . SER A 1 153 ? 23.751 -22.579 -18.514 1.00 34.47 ? 185 SER A C 1 ATOM 1196 O O . SER A 1 153 ? 22.727 -22.369 -19.163 1.00 34.31 ? 185 SER A O 1 ATOM 1197 C CB . SER A 1 153 ? 25.526 -24.292 -18.807 1.00 36.93 ? 185 SER A CB 1 ATOM 1198 O OG . SER A 1 153 ? 24.425 -25.139 -18.544 1.00 39.86 ? 185 SER A OG 1 ATOM 1199 N N . THR A 1 154 ? 23.818 -22.506 -17.171 1.00 33.52 ? 186 THR A N 1 ATOM 1200 C CA . THR A 1 154 ? 22.602 -22.303 -16.333 1.00 31.72 ? 186 THR A CA 1 ATOM 1201 C C . THR A 1 154 ? 22.054 -20.910 -16.495 1.00 29.66 ? 186 THR A C 1 ATOM 1202 O O . THR A 1 154 ? 20.843 -20.699 -16.385 1.00 27.97 ? 186 THR A O 1 ATOM 1203 C CB . THR A 1 154 ? 22.775 -22.558 -14.797 1.00 31.49 ? 186 THR A CB 1 ATOM 1204 O OG1 . THR A 1 154 ? 24.144 -22.419 -14.393 1.00 32.47 ? 186 THR A OG1 1 ATOM 1205 C CG2 . THR A 1 154 ? 22.269 -23.930 -14.409 1.00 31.35 ? 186 THR A CG2 1 ATOM 1206 N N . LEU A 1 155 ? 22.945 -19.960 -16.744 1.00 28.62 ? 187 LEU A N 1 ATOM 1207 C CA . LEU A 1 155 ? 22.519 -18.603 -17.016 1.00 30.00 ? 187 LEU A CA 1 ATOM 1208 C C . LEU A 1 155 ? 21.375 -18.528 -18.047 1.00 31.90 ? 187 LEU A C 1 ATOM 1209 O O . LEU A 1 155 ? 20.351 -17.933 -17.765 1.00 32.58 ? 187 LEU A O 1 ATOM 1210 C CB . LEU A 1 155 ? 23.713 -17.784 -17.465 1.00 29.97 ? 187 LEU A CB 1 ATOM 1211 C CG . LEU A 1 155 ? 23.490 -16.280 -17.561 1.00 30.46 ? 187 LEU A CG 1 ATOM 1212 C CD1 . LEU A 1 155 ? 22.617 -15.738 -16.444 1.00 30.37 ? 187 LEU A CD1 1 ATOM 1213 C CD2 . LEU A 1 155 ? 24.837 -15.574 -17.586 1.00 30.63 ? 187 LEU A CD2 1 ATOM 1214 N N . ARG A 1 156 ? 21.530 -19.177 -19.204 1.00 34.18 ? 188 ARG A N 1 ATOM 1215 C CA . ARG A 1 156 ? 20.469 -19.262 -20.235 1.00 35.64 ? 188 ARG A CA 1 ATOM 1216 C C . ARG A 1 156 ? 19.258 -20.105 -19.849 1.00 35.60 ? 188 ARG A C 1 ATOM 1217 O O . ARG A 1 156 ? 18.198 -19.951 -20.435 1.00 36.20 ? 188 ARG A O 1 ATOM 1218 C CB . ARG A 1 156 ? 20.966 -19.929 -21.515 1.00 38.98 ? 188 ARG A CB 1 ATOM 1219 C CG . ARG A 1 156 ? 22.365 -19.569 -22.007 1.00 41.85 ? 188 ARG A CG 1 ATOM 1220 C CD . ARG A 1 156 ? 22.838 -20.582 -23.055 1.00 41.16 ? 188 ARG A CD 1 ATOM 1221 N NE . ARG A 1 156 ? 24.201 -20.346 -23.512 1.00 38.98 ? 188 ARG A NE 1 ATOM 1222 C CZ . ARG A 1 156 ? 24.598 -19.302 -24.237 1.00 38.31 ? 188 ARG A CZ 1 ATOM 1223 N NH1 . ARG A 1 156 ? 23.762 -18.331 -24.616 1.00 37.13 1 188 ARG A NH1 1 ATOM 1224 N NH2 . ARG A 1 156 ? 25.867 -19.223 -24.580 1.00 40.00 ? 188 ARG A NH2 1 ATOM 1225 N N . LYS A 1 157 ? 19.439 -21.063 -18.949 1.00 35.49 ? 189 LYS A N 1 ATOM 1226 C CA . LYS A 1 157 ? 18.340 -21.925 -18.507 1.00 37.20 ? 189 LYS A CA 1 ATOM 1227 C C . LYS A 1 157 ? 17.287 -21.165 -17.647 1.00 37.50 ? 189 LYS A C 1 ATOM 1228 O O . LYS A 1 157 ? 16.069 -21.307 -17.869 1.00 34.59 ? 189 LYS A O 1 ATOM 1229 C CB . LYS A 1 157 ? 18.887 -23.131 -17.711 1.00 40.29 ? 189 LYS A CB 1 ATOM 1230 C CG . LYS A 1 157 ? 19.141 -24.439 -18.468 1.00 41.24 ? 189 LYS A CG 1 ATOM 1231 C CD . LYS A 1 157 ? 20.323 -24.376 -19.424 1.00 44.61 ? 189 LYS A CD 1 ATOM 1232 C CE . LYS A 1 157 ? 19.865 -24.186 -20.885 1.00 48.38 ? 189 LYS A CE 1 ATOM 1233 N NZ . LYS A 1 157 ? 20.891 -23.640 -21.836 1.00 47.95 1 189 LYS A NZ 1 ATOM 1234 N N . GLY A 1 158 ? 17.759 -20.386 -16.659 1.00 37.57 ? 190 GLY A N 1 ATOM 1235 C CA . GLY A 1 158 ? 16.863 -19.694 -15.703 1.00 34.95 ? 190 GLY A CA 1 ATOM 1236 C C . GLY A 1 158 ? 17.351 -18.413 -15.040 1.00 33.25 ? 190 GLY A C 1 ATOM 1237 O O . GLY A 1 158 ? 16.834 -18.025 -14.008 1.00 31.55 ? 190 GLY A O 1 ATOM 1238 N N . GLY A 1 159 ? 18.332 -17.739 -15.627 1.00 32.82 ? 191 GLY A N 1 ATOM 1239 C CA . GLY A 1 159 ? 18.832 -16.472 -15.076 1.00 32.08 ? 191 GLY A CA 1 ATOM 1240 C C . GLY A 1 159 ? 19.850 -16.542 -13.936 1.00 31.60 ? 191 GLY A C 1 ATOM 1241 O O . GLY A 1 159 ? 20.058 -15.551 -13.223 1.00 30.23 ? 191 GLY A O 1 ATOM 1242 N N . PHE A 1 160 ? 20.515 -17.684 -13.768 1.00 30.65 ? 192 PHE A N 1 ATOM 1243 C CA . PHE A 1 160 ? 21.469 -17.829 -12.681 1.00 28.80 ? 192 PHE A CA 1 ATOM 1244 C C . PHE A 1 160 ? 22.686 -18.690 -12.980 1.00 29.32 ? 192 PHE A C 1 ATOM 1245 O O . PHE A 1 160 ? 22.700 -19.462 -13.925 1.00 31.54 ? 192 PHE A O 1 ATOM 1246 C CB . PHE A 1 160 ? 20.750 -18.361 -11.467 1.00 27.26 ? 192 PHE A CB 1 ATOM 1247 C CG . PHE A 1 160 ? 20.107 -19.697 -11.658 1.00 26.87 ? 192 PHE A CG 1 ATOM 1248 C CD1 . PHE A 1 160 ? 20.839 -20.861 -11.504 1.00 27.21 ? 192 PHE A CD1 1 ATOM 1249 C CD2 . PHE A 1 160 ? 18.744 -19.798 -11.893 1.00 26.83 ? 192 PHE A CD2 1 ATOM 1250 C CE1 . PHE A 1 160 ? 20.222 -22.102 -11.611 1.00 26.97 ? 192 PHE A CE1 1 ATOM 1251 C CE2 . PHE A 1 160 ? 18.124 -21.032 -11.997 1.00 26.42 ? 192 PHE A CE2 1 ATOM 1252 C CZ . PHE A 1 160 ? 18.862 -22.185 -11.860 1.00 26.43 ? 192 PHE A CZ 1 ATOM 1253 N N . TYR A 1 161 ? 23.711 -18.548 -12.150 1.00 29.19 ? 193 TYR A N 1 ATOM 1254 C CA . TYR A 1 161 ? 24.957 -19.280 -12.316 1.00 29.43 ? 193 TYR A CA 1 ATOM 1255 C C . TYR A 1 161 ? 25.739 -19.191 -11.033 1.00 29.75 ? 193 TYR A C 1 ATOM 1256 O O . TYR A 1 161 ? 25.347 -18.477 -10.134 1.00 30.03 ? 193 TYR A O 1 ATOM 1257 C CB . TYR A 1 161 ? 25.794 -18.651 -13.424 1.00 29.73 ? 193 TYR A CB 1 ATOM 1258 C CG . TYR A 1 161 ? 26.272 -17.251 -13.092 1.00 29.56 ? 193 TYR A CG 1 ATOM 1259 C CD1 . TYR A 1 161 ? 25.465 -16.146 -13.317 1.00 29.19 ? 193 TYR A CD1 1 ATOM 1260 C CD2 . TYR A 1 161 ? 27.512 -17.035 -12.539 1.00 30.05 ? 193 TYR A CD2 1 ATOM 1261 C CE1 . TYR A 1 161 ? 25.886 -14.866 -13.018 1.00 27.86 ? 193 TYR A CE1 1 ATOM 1262 C CE2 . TYR A 1 161 ? 27.936 -15.751 -12.230 1.00 30.23 ? 193 TYR A CE2 1 ATOM 1263 C CZ . TYR A 1 161 ? 27.113 -14.671 -12.470 1.00 28.52 ? 193 TYR A CZ 1 ATOM 1264 O OH . TYR A 1 161 ? 27.539 -13.402 -12.161 1.00 27.93 ? 193 TYR A OH 1 ATOM 1265 N N . SER A 1 162 ? 26.858 -19.898 -10.967 1.00 30.55 ? 194 SER A N 1 ATOM 1266 C CA . SER A 1 162 ? 27.781 -19.794 -9.838 1.00 31.21 ? 194 SER A CA 1 ATOM 1267 C C . SER A 1 162 ? 29.171 -19.914 -10.379 1.00 31.27 ? 194 SER A C 1 ATOM 1268 O O . SER A 1 162 ? 29.381 -20.554 -11.394 1.00 32.08 ? 194 SER A O 1 ATOM 1269 C CB . SER A 1 162 ? 27.582 -20.925 -8.842 1.00 31.87 ? 194 SER A CB 1 ATOM 1270 O OG . SER A 1 162 ? 28.427 -22.015 -9.178 1.00 31.47 ? 194 SER A OG 1 ATOM 1271 N N . GLN A 1 163 ? 30.145 -19.363 -9.685 1.00 31.84 ? 195 GLN A N 1 ATOM 1272 C CA . GLN A 1 163 ? 31.409 -19.150 -10.339 1.00 33.17 ? 195 GLN A CA 1 ATOM 1273 C C . GLN A 1 163 ? 32.534 -18.919 -9.359 1.00 33.29 ? 195 GLN A C 1 ATOM 1274 O O . GLN A 1 163 ? 32.447 -18.041 -8.515 1.00 35.22 ? 195 GLN A O 1 ATOM 1275 C CB . GLN A 1 163 ? 31.252 -17.929 -11.252 1.00 34.41 ? 195 GLN A CB 1 ATOM 1276 C CG . GLN A 1 163 ? 32.488 -17.527 -12.038 1.00 36.04 ? 195 GLN A CG 1 ATOM 1277 C CD . GLN A 1 163 ? 32.906 -18.564 -13.051 1.00 36.31 ? 195 GLN A CD 1 ATOM 1278 O OE1 . GLN A 1 163 ? 32.061 -19.248 -13.652 1.00 37.42 ? 195 GLN A OE1 1 ATOM 1279 N NE2 . GLN A 1 163 ? 34.211 -18.683 -13.259 1.00 35.97 ? 195 GLN A NE2 1 ATOM 1280 N N . LYS A 1 164 ? 33.601 -19.693 -9.496 1.00 33.15 ? 196 LYS A N 1 ATOM 1281 C CA . LYS A 1 164 ? 34.802 -19.468 -8.723 1.00 33.21 ? 196 LYS A CA 1 ATOM 1282 C C . LYS A 1 164 ? 35.354 -18.166 -9.195 1.00 31.19 ? 196 LYS A C 1 ATOM 1283 O O . LYS A 1 164 ? 35.214 -17.837 -10.349 1.00 29.82 ? 196 LYS A O 1 ATOM 1284 C CB . LYS A 1 164 ? 35.823 -20.583 -8.961 1.00 37.09 ? 196 LYS A CB 1 ATOM 1285 C CG . LYS A 1 164 ? 35.385 -21.941 -8.399 1.00 41.54 ? 196 LYS A CG 1 ATOM 1286 C CD . LYS A 1 164 ? 36.247 -23.133 -8.855 1.00 43.26 ? 196 LYS A CD 1 ATOM 1287 C CE . LYS A 1 164 ? 35.756 -23.771 -10.154 1.00 43.37 ? 196 LYS A CE 1 ATOM 1288 N NZ . LYS A 1 164 ? 35.824 -25.250 -10.036 1.00 43.01 1 196 LYS A NZ 1 ATOM 1289 N N . VAL A 1 165 ? 35.965 -17.412 -8.303 1.00 32.47 ? 197 VAL A N 1 ATOM 1290 C CA . VAL A 1 165 ? 36.554 -16.150 -8.691 1.00 34.81 ? 197 VAL A CA 1 ATOM 1291 C C . VAL A 1 165 ? 37.936 -16.433 -9.234 1.00 36.50 ? 197 VAL A C 1 ATOM 1292 O O . VAL A 1 165 ? 38.750 -17.085 -8.569 1.00 34.97 ? 197 VAL A O 1 ATOM 1293 C CB . VAL A 1 165 ? 36.706 -15.194 -7.498 1.00 36.40 ? 197 VAL A CB 1 ATOM 1294 C CG1 . VAL A 1 165 ? 37.336 -13.879 -7.940 1.00 37.47 ? 197 VAL A CG1 1 ATOM 1295 C CG2 . VAL A 1 165 ? 35.366 -14.931 -6.848 1.00 37.16 ? 197 VAL A CG2 1 ATOM 1296 N N . THR A 1 166 ? 38.207 -15.928 -10.433 1.00 39.02 ? 198 THR A N 1 ATOM 1297 C CA . THR A 1 166 ? 39.532 -16.065 -11.040 1.00 39.58 ? 198 THR A CA 1 ATOM 1298 C C . THR A 1 166 ? 40.593 -15.823 -9.975 1.00 38.69 ? 198 THR A C 1 ATOM 1299 O O . THR A 1 166 ? 41.314 -16.732 -9.638 1.00 41.29 ? 198 THR A O 1 ATOM 1300 C CB . THR A 1 166 ? 39.726 -15.101 -12.242 1.00 39.04 ? 198 THR A CB 1 ATOM 1301 O OG1 . THR A 1 166 ? 39.062 -15.645 -13.386 1.00 34.35 ? 198 THR A OG1 1 ATOM 1302 C CG2 . THR A 1 166 ? 41.231 -14.848 -12.570 1.00 38.11 ? 198 THR A CG2 1 ATOM 1303 N N . THR A 1 167 ? 40.646 -14.627 -9.408 1.00 37.38 ? 199 THR A N 1 ATOM 1304 C CA . THR A 1 167 ? 41.759 -14.267 -8.522 1.00 38.23 ? 199 THR A CA 1 ATOM 1305 C C . THR A 1 167 ? 41.707 -14.854 -7.109 1.00 34.45 ? 199 THR A C 1 ATOM 1306 O O . THR A 1 167 ? 42.547 -14.498 -6.293 1.00 29.87 ? 199 THR A O 1 ATOM 1307 C CB . THR A 1 167 ? 41.901 -12.728 -8.379 1.00 41.07 ? 199 THR A CB 1 ATOM 1308 O OG1 . THR A 1 167 ? 40.739 -12.176 -7.738 1.00 44.25 ? 199 THR A OG1 1 ATOM 1309 C CG2 . THR A 1 167 ? 42.075 -12.085 -9.739 1.00 40.70 ? 199 THR A CG2 1 ATOM 1310 N N . ASN A 1 168 ? 40.747 -15.696 -6.819 1.00 32.97 ? 200 ASN A N 1 ATOM 1311 C CA . ASN A 1 168 ? 40.607 -16.294 -5.518 1.00 35.77 ? 200 ASN A CA 1 ATOM 1312 C C . ASN A 1 168 ? 39.746 -17.426 -5.921 1.00 40.50 ? 200 ASN A C 1 ATOM 1313 O O . ASN A 1 168 ? 38.560 -17.303 -5.993 1.00 44.48 ? 200 ASN A O 1 ATOM 1314 C CB . ASN A 1 168 ? 39.821 -15.388 -4.594 1.00 35.39 ? 200 ASN A CB 1 ATOM 1315 C CG . ASN A 1 168 ? 40.466 -14.060 -4.367 1.00 35.34 ? 200 ASN A CG 1 ATOM 1316 O OD1 . ASN A 1 168 ? 41.253 -13.886 -3.461 1.00 36.30 ? 200 ASN A OD1 1 ATOM 1317 N ND2 . ASN A 1 168 ? 40.077 -13.103 -5.141 1.00 34.64 ? 200 ASN A ND2 1 ATOM 1318 N N . PRO A 1 169 ? 40.307 -18.557 -6.230 1.00 42.84 ? 201 PRO A N 1 ATOM 1319 C CA . PRO A 1 169 ? 39.431 -19.597 -6.787 1.00 42.41 ? 201 PRO A CA 1 ATOM 1320 C C . PRO A 1 169 ? 38.788 -20.578 -5.810 1.00 41.34 ? 201 PRO A C 1 ATOM 1321 O O . PRO A 1 169 ? 38.177 -21.549 -6.264 1.00 42.20 ? 201 PRO A O 1 ATOM 1322 C CB . PRO A 1 169 ? 40.344 -20.338 -7.763 1.00 44.35 ? 201 PRO A CB 1 ATOM 1323 C CG . PRO A 1 169 ? 41.628 -19.548 -7.805 1.00 45.11 ? 201 PRO A CG 1 ATOM 1324 C CD . PRO A 1 169 ? 41.719 -18.795 -6.522 1.00 43.87 ? 201 PRO A CD 1 ATOM 1325 N N . ASN A 1 170 ? 38.928 -20.358 -4.502 1.00 40.92 ? 202 ASN A N 1 ATOM 1326 C CA . ASN A 1 170 ? 38.113 -21.093 -3.510 1.00 41.69 ? 202 ASN A CA 1 ATOM 1327 C C . ASN A 1 170 ? 37.017 -20.199 -2.924 1.00 41.84 ? 202 ASN A C 1 ATOM 1328 O O . ASN A 1 170 ? 36.330 -20.561 -1.965 1.00 44.08 ? 202 ASN A O 1 ATOM 1329 C CB . ASN A 1 170 ? 38.977 -21.697 -2.407 1.00 41.18 ? 202 ASN A CB 1 ATOM 1330 C CG . ASN A 1 170 ? 39.879 -20.680 -1.763 1.00 41.18 ? 202 ASN A CG 1 ATOM 1331 O OD1 . ASN A 1 170 ? 40.311 -19.720 -2.411 1.00 38.92 ? 202 ASN A OD1 1 ATOM 1332 N ND2 . ASN A 1 170 ? 40.177 -20.883 -0.484 1.00 41.90 ? 202 ASN A ND2 1 ATOM 1333 N N . LEU A 1 171 ? 36.869 -19.026 -3.529 1.00 40.30 ? 203 LEU A N 1 ATOM 1334 C CA . LEU A 1 171 ? 35.717 -18.178 -3.345 1.00 37.75 ? 203 LEU A CA 1 ATOM 1335 C C . LEU A 1 171 ? 34.783 -18.409 -4.520 1.00 36.47 ? 203 LEU A C 1 ATOM 1336 O O . LEU A 1 171 ? 35.177 -18.187 -5.662 1.00 36.12 ? 203 LEU A O 1 ATOM 1337 C CB . LEU A 1 171 ? 36.168 -16.721 -3.350 1.00 36.71 ? 203 LEU A CB 1 ATOM 1338 C CG . LEU A 1 171 ? 35.071 -15.714 -3.064 1.00 36.35 ? 203 LEU A CG 1 ATOM 1339 C CD1 . LEU A 1 171 ? 34.428 -16.064 -1.734 1.00 36.47 ? 203 LEU A CD1 1 ATOM 1340 C CD2 . LEU A 1 171 ? 35.620 -14.297 -3.066 1.00 35.39 ? 203 LEU A CD2 1 ATOM 1341 N N . ARG A 1 172 ? 33.557 -18.845 -4.256 1.00 34.89 ? 204 ARG A N 1 ATOM 1342 C CA . ARG A 1 172 ? 32.559 -18.973 -5.325 1.00 33.91 ? 204 ARG A CA 1 ATOM 1343 C C . ARG A 1 172 ? 31.398 -17.992 -5.190 1.00 29.93 ? 204 ARG A C 1 ATOM 1344 O O . ARG A 1 172 ? 30.636 -18.048 -4.238 1.00 29.32 ? 204 ARG A O 1 ATOM 1345 C CB . ARG A 1 172 ? 31.986 -20.390 -5.374 1.00 36.82 ? 204 ARG A CB 1 ATOM 1346 C CG . ARG A 1 172 ? 30.774 -20.557 -6.305 1.00 39.31 ? 204 ARG A CG 1 ATOM 1347 C CD . ARG A 1 172 ? 30.085 -21.902 -6.078 1.00 41.55 ? 204 ARG A CD 1 ATOM 1348 N NE . ARG A 1 172 ? 31.028 -23.025 -6.085 1.00 42.45 ? 204 ARG A NE 1 ATOM 1349 C CZ . ARG A 1 172 ? 31.564 -23.558 -7.182 1.00 42.71 ? 204 ARG A CZ 1 ATOM 1350 N NH1 . ARG A 1 172 ? 31.269 -23.093 -8.393 1.00 44.09 1 204 ARG A NH1 1 ATOM 1351 N NH2 . ARG A 1 172 ? 32.416 -24.558 -7.067 1.00 42.91 ? 204 ARG A NH2 1 ATOM 1352 N N . ILE A 1 173 ? 31.236 -17.137 -6.184 1.00 26.30 ? 205 ILE A N 1 ATOM 1353 C CA . ILE A 1 173 ? 30.107 -16.259 -6.230 1.00 25.29 ? 205 ILE A CA 1 ATOM 1354 C C . ILE A 1 173 ? 28.940 -17.071 -6.724 1.00 24.73 ? 205 ILE A C 1 ATOM 1355 O O . ILE A 1 173 ? 29.040 -17.696 -7.768 1.00 24.96 ? 205 ILE A O 1 ATOM 1356 C CB . ILE A 1 173 ? 30.320 -15.107 -7.225 1.00 26.08 ? 205 ILE A CB 1 ATOM 1357 C CG1 . ILE A 1 173 ? 31.607 -14.308 -6.918 1.00 26.53 ? 205 ILE A CG1 1 ATOM 1358 C CG2 . ILE A 1 173 ? 29.110 -14.187 -7.223 1.00 26.16 ? 205 ILE A CG2 1 ATOM 1359 C CD1 . ILE A 1 173 ? 31.727 -13.756 -5.500 1.00 26.13 ? 205 ILE A CD1 1 ATOM 1360 N N . ILE A 1 174 ? 27.845 -17.068 -5.968 1.00 24.35 ? 206 ILE A N 1 ATOM 1361 C CA . ILE A 1 174 ? 26.549 -17.617 -6.418 1.00 23.60 ? 206 ILE A CA 1 ATOM 1362 C C . ILE A 1 174 ? 25.590 -16.474 -6.800 1.00 22.80 ? 206 ILE A C 1 ATOM 1363 O O . ILE A 1 174 ? 25.025 -15.830 -5.929 1.00 22.93 ? 206 ILE A O 1 ATOM 1364 C CB . ILE A 1 174 ? 25.864 -18.465 -5.312 1.00 23.11 ? 206 ILE A CB 1 ATOM 1365 C CG1 . ILE A 1 174 ? 26.700 -19.690 -4.953 1.00 22.76 ? 206 ILE A CG1 1 ATOM 1366 C CG2 . ILE A 1 174 ? 24.458 -18.895 -5.727 1.00 23.03 ? 206 ILE A CG2 1 ATOM 1367 C CD1 . ILE A 1 174 ? 26.080 -20.535 -3.853 1.00 22.15 ? 206 ILE A CD1 1 ATOM 1368 N N . SER A 1 175 ? 25.399 -16.234 -8.095 1.00 22.48 ? 207 SER A N 1 ATOM 1369 C CA . SER A 1 175 ? 24.443 -15.230 -8.564 1.00 22.13 ? 207 SER A CA 1 ATOM 1370 C C . SER A 1 175 ? 23.058 -15.836 -8.746 1.00 22.32 ? 207 SER A C 1 ATOM 1371 O O . SER A 1 175 ? 22.867 -16.698 -9.584 1.00 21.35 ? 207 SER A O 1 ATOM 1372 C CB . SER A 1 175 ? 24.896 -14.594 -9.884 1.00 22.02 ? 207 SER A CB 1 ATOM 1373 O OG . SER A 1 175 ? 23.894 -13.714 -10.398 1.00 21.57 ? 207 SER A OG 1 ATOM 1374 N N . LEU A 1 176 ? 22.094 -15.348 -7.967 1.00 23.95 ? 208 LEU A N 1 ATOM 1375 C CA . LEU A 1 176 ? 20.717 -15.830 -8.009 1.00 24.23 ? 208 LEU A CA 1 ATOM 1376 C C . LEU A 1 176 ? 19.773 -14.890 -8.716 1.00 24.08 ? 208 LEU A C 1 ATOM 1377 O O . LEU A 1 176 ? 19.890 -13.641 -8.689 1.00 23.76 ? 208 LEU A O 1 ATOM 1378 C CB . LEU A 1 176 ? 20.162 -16.041 -6.607 1.00 25.23 ? 208 LEU A CB 1 ATOM 1379 C CG . LEU A 1 176 ? 20.757 -17.154 -5.734 1.00 26.80 ? 208 LEU A CG 1 ATOM 1380 C CD1 . LEU A 1 176 ? 20.330 -16.891 -4.295 1.00 27.26 ? 208 LEU A CD1 1 ATOM 1381 C CD2 . LEU A 1 176 ? 20.340 -18.561 -6.165 1.00 26.43 ? 208 LEU A CD2 1 ATOM 1382 N N . ASN A 1 177 ? 18.801 -15.523 -9.344 1.00 24.17 ? 209 ASN A N 1 ATOM 1383 C CA . ASN A 1 177 ? 17.706 -14.804 -9.911 1.00 24.39 ? 209 ASN A CA 1 ATOM 1384 C C . ASN A 1 177 ? 16.586 -14.926 -8.934 1.00 22.83 ? 209 ASN A C 1 ATOM 1385 O O . ASN A 1 177 ? 15.822 -15.892 -8.966 1.00 22.14 ? 209 ASN A O 1 ATOM 1386 C CB . ASN A 1 177 ? 17.298 -15.377 -11.247 1.00 25.52 ? 209 ASN A CB 1 ATOM 1387 C CG . ASN A 1 177 ? 16.118 -14.654 -11.832 1.00 26.46 ? 209 ASN A CG 1 ATOM 1388 O OD1 . ASN A 1 177 ? 15.546 -13.762 -11.209 1.00 27.17 ? 209 ASN A OD1 1 ATOM 1389 N ND2 . ASN A 1 177 ? 15.737 -15.041 -13.027 1.00 27.73 ? 209 ASN A ND2 1 ATOM 1390 N N . THR A 1 178 ? 16.511 -13.930 -8.060 1.00 21.44 ? 210 THR A N 1 ATOM 1391 C CA . THR A 1 178 ? 15.487 -13.880 -7.056 1.00 20.47 ? 210 THR A CA 1 ATOM 1392 C C . THR A 1 178 ? 14.281 -13.164 -7.623 1.00 21.27 ? 210 THR A C 1 ATOM 1393 O O . THR A 1 178 ? 13.227 -13.143 -6.985 1.00 23.67 ? 210 THR A O 1 ATOM 1394 C CB . THR A 1 178 ? 15.993 -13.208 -5.779 1.00 19.65 ? 210 THR A CB 1 ATOM 1395 O OG1 . THR A 1 178 ? 16.764 -12.038 -6.102 1.00 19.18 ? 210 THR A OG1 1 ATOM 1396 C CG2 . THR A 1 178 ? 16.870 -14.187 -5.035 1.00 19.53 ? 210 THR A CG2 1 ATOM 1397 N N . ASN A 1 179 ? 14.404 -12.621 -8.835 1.00 19.80 ? 211 ASN A N 1 ATOM 1398 C CA . ASN A 1 179 ? 13.250 -12.067 -9.502 1.00 19.36 ? 211 ASN A CA 1 ATOM 1399 C C . ASN A 1 179 ? 12.202 -13.144 -9.743 1.00 19.84 ? 211 ASN A C 1 ATOM 1400 O O . ASN A 1 179 ? 11.013 -12.847 -9.921 1.00 19.44 ? 211 ASN A O 1 ATOM 1401 C CB . ASN A 1 179 ? 13.648 -11.438 -10.819 1.00 19.22 ? 211 ASN A CB 1 ATOM 1402 C CG . ASN A 1 179 ? 14.783 -10.453 -10.676 1.00 18.93 ? 211 ASN A CG 1 ATOM 1403 O OD1 . ASN A 1 179 ? 15.847 -10.615 -11.251 1.00 18.87 ? 211 ASN A OD1 1 ATOM 1404 N ND2 . ASN A 1 179 ? 14.553 -9.421 -9.917 1.00 18.94 ? 211 ASN A ND2 1 ATOM 1405 N N . LEU A 1 180 ? 12.651 -14.393 -9.745 1.00 20.94 ? 212 LEU A N 1 ATOM 1406 C CA . LEU A 1 180 ? 11.749 -15.547 -9.841 1.00 23.08 ? 212 LEU A CA 1 ATOM 1407 C C . LEU A 1 180 ? 10.771 -15.559 -8.665 1.00 24.09 ? 212 LEU A C 1 ATOM 1408 O O . LEU A 1 180 ? 9.658 -16.113 -8.785 1.00 26.87 ? 212 LEU A O 1 ATOM 1409 C CB . LEU A 1 180 ? 12.532 -16.886 -9.901 1.00 23.21 ? 212 LEU A CB 1 ATOM 1410 C CG . LEU A 1 180 ? 13.540 -16.958 -11.073 1.00 23.59 ? 212 LEU A CG 1 ATOM 1411 C CD1 . LEU A 1 180 ? 14.499 -18.132 -10.993 1.00 23.34 ? 212 LEU A CD1 1 ATOM 1412 C CD2 . LEU A 1 180 ? 12.823 -16.950 -12.419 1.00 23.59 ? 212 LEU A CD2 1 ATOM 1413 N N . TYR A 1 181 ? 11.179 -14.937 -7.550 1.00 22.16 ? 213 TYR A N 1 ATOM 1414 C CA . TYR A 1 181 ? 10.426 -14.954 -6.319 1.00 20.31 ? 213 TYR A CA 1 ATOM 1415 C C . TYR A 1 181 ? 9.701 -13.678 -6.047 1.00 17.70 ? 213 TYR A C 1 ATOM 1416 O O . TYR A 1 181 ? 9.023 -13.560 -5.062 1.00 16.08 ? 213 TYR A O 1 ATOM 1417 C CB . TYR A 1 181 ? 11.387 -15.244 -5.193 1.00 22.43 ? 213 TYR A CB 1 ATOM 1418 C CG . TYR A 1 181 ? 12.208 -16.489 -5.453 1.00 25.15 ? 213 TYR A CG 1 ATOM 1419 C CD1 . TYR A 1 181 ? 11.595 -17.679 -5.861 1.00 25.89 ? 213 TYR A CD1 1 ATOM 1420 C CD2 . TYR A 1 181 ? 13.592 -16.481 -5.297 1.00 26.22 ? 213 TYR A CD2 1 ATOM 1421 C CE1 . TYR A 1 181 ? 12.339 -18.810 -6.102 1.00 27.65 ? 213 TYR A CE1 1 ATOM 1422 C CE2 . TYR A 1 181 ? 14.345 -17.621 -5.531 1.00 27.42 ? 213 TYR A CE2 1 ATOM 1423 C CZ . TYR A 1 181 ? 13.712 -18.776 -5.936 1.00 28.56 ? 213 TYR A CZ 1 ATOM 1424 O OH . TYR A 1 181 ? 14.437 -19.909 -6.189 1.00 30.59 ? 213 TYR A OH 1 ATOM 1425 N N . TYR A 1 182 ? 9.826 -12.723 -6.946 1.00 17.01 ? 214 TYR A N 1 ATOM 1426 C CA . TYR A 1 182 ? 9.213 -11.419 -6.773 1.00 17.05 ? 214 TYR A CA 1 ATOM 1427 C C . TYR A 1 182 ? 7.727 -11.475 -7.007 1.00 17.47 ? 214 TYR A C 1 ATOM 1428 O O . TYR A 1 182 ? 7.271 -12.144 -7.920 1.00 17.48 ? 214 TYR A O 1 ATOM 1429 C CB . TYR A 1 182 ? 9.838 -10.463 -7.759 1.00 17.21 ? 214 TYR A CB 1 ATOM 1430 C CG . TYR A 1 182 ? 9.526 -8.993 -7.592 1.00 17.42 ? 214 TYR A CG 1 ATOM 1431 C CD1 . TYR A 1 182 ? 9.382 -8.418 -6.349 1.00 16.93 ? 214 TYR A CD1 1 ATOM 1432 C CD2 . TYR A 1 182 ? 9.460 -8.161 -8.727 1.00 18.22 ? 214 TYR A CD2 1 ATOM 1433 C CE1 . TYR A 1 182 ? 9.130 -7.076 -6.232 1.00 17.51 ? 214 TYR A CE1 1 ATOM 1434 C CE2 . TYR A 1 182 ? 9.200 -6.816 -8.622 1.00 17.90 ? 214 TYR A CE2 1 ATOM 1435 C CZ . TYR A 1 182 ? 9.039 -6.283 -7.368 1.00 18.00 ? 214 TYR A CZ 1 ATOM 1436 O OH . TYR A 1 182 ? 8.798 -4.939 -7.251 1.00 19.18 ? 214 TYR A OH 1 ATOM 1437 N N . GLY A 1 183 ? 6.978 -10.771 -6.167 1.00 18.61 ? 215 GLY A N 1 ATOM 1438 C CA . GLY A 1 183 ? 5.500 -10.751 -6.206 1.00 18.87 ? 215 GLY A CA 1 ATOM 1439 C C . GLY A 1 183 ? 4.905 -10.613 -7.590 1.00 19.21 ? 215 GLY A C 1 ATOM 1440 O O . GLY A 1 183 ? 4.326 -11.570 -8.097 1.00 19.31 ? 215 GLY A O 1 ATOM 1441 N N . PRO A 1 184 ? 5.092 -9.449 -8.240 1.00 20.00 ? 216 PRO A N 1 ATOM 1442 C CA . PRO A 1 184 ? 4.540 -9.193 -9.592 1.00 20.77 ? 216 PRO A CA 1 ATOM 1443 C C . PRO A 1 184 ? 4.874 -10.196 -10.702 1.00 21.78 ? 216 PRO A C 1 ATOM 1444 O O . PRO A 1 184 ? 4.428 -9.987 -11.840 1.00 22.50 ? 216 PRO A O 1 ATOM 1445 C CB . PRO A 1 184 ? 5.146 -7.842 -9.979 1.00 20.08 ? 216 PRO A CB 1 ATOM 1446 C CG . PRO A 1 184 ? 5.488 -7.202 -8.684 1.00 19.97 ? 216 PRO A CG 1 ATOM 1447 C CD . PRO A 1 184 ? 5.859 -8.297 -7.736 1.00 19.73 ? 216 PRO A CD 1 ATOM 1448 N N . ASN A 1 185 ? 5.636 -11.247 -10.407 1.00 22.86 ? 217 ASN A N 1 ATOM 1449 C CA . ASN A 1 185 ? 6.091 -12.153 -11.453 1.00 25.62 ? 217 ASN A CA 1 ATOM 1450 C C . ASN A 1 185 ? 5.088 -13.251 -11.745 1.00 27.97 ? 217 ASN A C 1 ATOM 1451 O O . ASN A 1 185 ? 5.090 -14.319 -11.096 1.00 28.33 ? 217 ASN A O 1 ATOM 1452 C CB . ASN A 1 185 ? 7.439 -12.772 -11.105 1.00 26.86 ? 217 ASN A CB 1 ATOM 1453 C CG . ASN A 1 185 ? 8.032 -13.554 -12.257 1.00 27.37 ? 217 ASN A CG 1 ATOM 1454 O OD1 . ASN A 1 185 ? 7.477 -13.584 -13.344 1.00 28.21 ? 217 ASN A OD1 1 ATOM 1455 N ND2 . ASN A 1 185 ? 9.178 -14.176 -12.025 1.00 28.48 ? 217 ASN A ND2 1 ATOM 1456 N N . ILE A 1 186 ? 4.272 -12.995 -12.770 1.00 29.26 ? 218 ILE A N 1 ATOM 1457 C CA . ILE A 1 186 ? 3.147 -13.854 -13.118 1.00 29.71 ? 218 ILE A CA 1 ATOM 1458 C C . ILE A 1 186 ? 3.597 -15.241 -13.577 1.00 30.51 ? 218 ILE A C 1 ATOM 1459 O O . ILE A 1 186 ? 2.878 -16.223 -13.377 1.00 29.77 ? 218 ILE A O 1 ATOM 1460 C CB . ILE A 1 186 ? 2.287 -13.224 -14.220 1.00 29.86 ? 218 ILE A CB 1 ATOM 1461 C CG1 . ILE A 1 186 ? 1.785 -11.835 -13.804 1.00 31.47 ? 218 ILE A CG1 1 ATOM 1462 C CG2 . ILE A 1 186 ? 1.121 -14.132 -14.569 1.00 30.33 ? 218 ILE A CG2 1 ATOM 1463 C CD1 . ILE A 1 186 ? 0.671 -11.815 -12.771 1.00 33.38 ? 218 ILE A CD1 1 ATOM 1464 N N . MET A 1 187 ? 4.786 -15.321 -14.172 1.00 31.88 ? 219 MET A N 1 ATOM 1465 C CA . MET A 1 187 ? 5.344 -16.605 -14.623 1.00 34.52 ? 219 MET A CA 1 ATOM 1466 C C . MET A 1 187 ? 5.388 -17.655 -13.517 1.00 34.52 ? 219 MET A C 1 ATOM 1467 O O . MET A 1 187 ? 5.077 -18.811 -13.761 1.00 34.10 ? 219 MET A O 1 ATOM 1468 C CB . MET A 1 187 ? 6.756 -16.417 -15.192 1.00 36.85 ? 219 MET A CB 1 ATOM 1469 C CG . MET A 1 187 ? 6.840 -15.487 -16.399 1.00 39.80 ? 219 MET A CG 1 ATOM 1470 S SD . MET A 1 187 ? 5.705 -15.973 -17.720 1.00 44.07 ? 219 MET A SD 1 ATOM 1471 C CE . MET A 1 187 ? 4.218 -14.994 -17.390 1.00 43.75 ? 219 MET A CE 1 ATOM 1472 N N . THR A 1 188 ? 5.731 -17.238 -12.299 1.00 35.19 ? 220 THR A N 1 ATOM 1473 C CA . THR A 1 188 ? 6.056 -18.167 -11.229 1.00 34.62 ? 220 THR A CA 1 ATOM 1474 C C . THR A 1 188 ? 4.956 -18.400 -10.200 1.00 33.55 ? 220 THR A C 1 ATOM 1475 O O . THR A 1 188 ? 5.196 -19.056 -9.199 1.00 33.61 ? 220 THR A O 1 ATOM 1476 C CB . THR A 1 188 ? 7.320 -17.692 -10.469 1.00 36.41 ? 220 THR A CB 1 ATOM 1477 O OG1 . THR A 1 188 ? 7.065 -16.427 -9.845 1.00 36.26 ? 220 THR A OG1 1 ATOM 1478 C CG2 . THR A 1 188 ? 8.519 -17.571 -11.421 1.00 36.88 ? 220 THR A CG2 1 ATOM 1479 N N . LEU A 1 189 ? 3.755 -17.883 -10.410 1.00 34.22 ? 221 LEU A N 1 ATOM 1480 C CA . LEU A 1 189 ? 2.672 -18.169 -9.451 1.00 34.92 ? 221 LEU A CA 1 ATOM 1481 C C . LEU A 1 189 ? 2.495 -19.654 -9.223 1.00 39.01 ? 221 LEU A C 1 ATOM 1482 O O . LEU A 1 189 ? 2.656 -20.463 -10.136 1.00 42.33 ? 221 LEU A O 1 ATOM 1483 C CB . LEU A 1 189 ? 1.345 -17.589 -9.910 1.00 32.50 ? 221 LEU A CB 1 ATOM 1484 C CG . LEU A 1 189 ? 1.234 -16.154 -9.411 1.00 32.17 ? 221 LEU A CG 1 ATOM 1485 C CD1 . LEU A 1 189 ? 0.525 -15.244 -10.402 1.00 32.64 ? 221 LEU A CD1 1 ATOM 1486 C CD2 . LEU A 1 189 ? 0.542 -16.142 -8.068 1.00 31.32 ? 221 LEU A CD2 1 ATOM 1487 N N . ASN A 1 190 ? 2.190 -20.008 -7.982 1.00 41.20 ? 222 ASN A N 1 ATOM 1488 C CA . ASN A 1 190 ? 1.860 -21.378 -7.615 1.00 42.22 ? 222 ASN A CA 1 ATOM 1489 C C . ASN A 1 190 ? 2.943 -22.435 -7.902 1.00 39.97 ? 222 ASN A C 1 ATOM 1490 O O . ASN A 1 190 ? 2.657 -23.623 -7.840 1.00 38.97 ? 222 ASN A O 1 ATOM 1491 C CB . ASN A 1 190 ? 0.510 -21.782 -8.251 1.00 44.77 ? 222 ASN A CB 1 ATOM 1492 C CG . ASN A 1 190 ? -0.383 -22.558 -7.283 1.00 49.91 ? 222 ASN A CG 1 ATOM 1493 O OD1 . ASN A 1 190 ? -0.621 -22.115 -6.148 1.00 53.06 ? 222 ASN A OD1 1 ATOM 1494 N ND2 . ASN A 1 190 ? -0.876 -23.721 -7.716 1.00 51.89 ? 222 ASN A ND2 1 ATOM 1495 N N . LYS A 1 191 ? 4.179 -22.015 -8.169 1.00 40.77 ? 223 LYS A N 1 ATOM 1496 C CA . LYS A 1 191 ? 5.279 -22.960 -8.393 1.00 43.48 ? 223 LYS A CA 1 ATOM 1497 C C . LYS A 1 191 ? 6.086 -23.246 -7.137 1.00 43.88 ? 223 LYS A C 1 ATOM 1498 O O . LYS A 1 191 ? 6.765 -22.378 -6.598 1.00 40.08 ? 223 LYS A O 1 ATOM 1499 C CB . LYS A 1 191 ? 6.238 -22.455 -9.458 1.00 45.42 ? 223 LYS A CB 1 ATOM 1500 C CG . LYS A 1 191 ? 5.648 -22.409 -10.847 1.00 47.19 ? 223 LYS A CG 1 ATOM 1501 C CD . LYS A 1 191 ? 6.694 -22.759 -11.892 1.00 48.64 ? 223 LYS A CD 1 ATOM 1502 C CE . LYS A 1 191 ? 6.209 -22.385 -13.282 1.00 49.66 ? 223 LYS A CE 1 ATOM 1503 N NZ . LYS A 1 191 ? 6.709 -23.328 -14.315 1.00 51.57 1 223 LYS A NZ 1 ATOM 1504 N N . THR A 1 192 ? 5.993 -24.489 -6.692 1.00 48.72 ? 224 THR A N 1 ATOM 1505 C CA . THR A 1 192 ? 6.861 -25.052 -5.657 1.00 49.49 ? 224 THR A CA 1 ATOM 1506 C C . THR A 1 192 ? 8.327 -24.583 -5.717 1.00 47.15 ? 224 THR A C 1 ATOM 1507 O O . THR A 1 192 ? 8.885 -24.202 -4.698 1.00 43.31 ? 224 THR A O 1 ATOM 1508 C CB . THR A 1 192 ? 6.860 -26.602 -5.737 1.00 52.63 ? 224 THR A CB 1 ATOM 1509 O OG1 . THR A 1 192 ? 7.860 -27.114 -4.858 1.00 55.30 ? 224 THR A OG1 1 ATOM 1510 C CG2 . THR A 1 192 ? 7.150 -27.145 -7.195 1.00 53.33 ? 224 THR A CG2 1 ATOM 1511 N N . ASP A 1 193 ? 8.943 -24.635 -6.902 1.00 45.44 ? 225 ASP A N 1 ATOM 1512 C CA . ASP A 1 193 ? 10.356 -24.288 -7.068 1.00 43.78 ? 225 ASP A CA 1 ATOM 1513 C C . ASP A 1 193 ? 10.607 -23.862 -8.499 1.00 42.15 ? 225 ASP A C 1 ATOM 1514 O O . ASP A 1 193 ? 10.876 -24.693 -9.361 1.00 43.62 ? 225 ASP A O 1 ATOM 1515 C CB . ASP A 1 193 ? 11.299 -25.449 -6.712 1.00 43.69 ? 225 ASP A CB 1 ATOM 1516 C CG . ASP A 1 193 ? 12.786 -25.072 -6.871 1.00 44.88 ? 225 ASP A CG 1 ATOM 1517 O OD1 . ASP A 1 193 ? 13.095 -23.898 -7.213 1.00 46.29 ? 225 ASP A OD1 1 ATOM 1518 O OD2 . ASP A 1 193 ? 13.650 -25.945 -6.642 1.00 43.98 -1 225 ASP A OD2 1 ATOM 1519 N N . PRO A 1 194 ? 10.525 -22.554 -8.756 1.00 39.55 ? 226 PRO A N 1 ATOM 1520 C CA . PRO A 1 194 ? 10.769 -22.041 -10.096 1.00 37.24 ? 226 PRO A CA 1 ATOM 1521 C C . PRO A 1 194 ? 12.189 -22.314 -10.542 1.00 33.00 ? 226 PRO A C 1 ATOM 1522 O O . PRO A 1 194 ? 13.112 -22.130 -9.765 1.00 33.17 ? 226 PRO A O 1 ATOM 1523 C CB . PRO A 1 194 ? 10.529 -20.535 -9.965 1.00 38.05 ? 226 PRO A CB 1 ATOM 1524 C CG . PRO A 1 194 ? 9.714 -20.371 -8.743 1.00 38.53 ? 226 PRO A CG 1 ATOM 1525 C CD . PRO A 1 194 ? 10.009 -21.526 -7.844 1.00 38.61 ? 226 PRO A CD 1 ATOM 1526 N N . ALA A 1 195 ? 12.310 -22.771 -11.782 1.00 29.67 ? 227 ALA A N 1 ATOM 1527 C CA . ALA A 1 195 ? 13.565 -23.098 -12.451 1.00 27.85 ? 227 ALA A CA 1 ATOM 1528 C C . ALA A 1 195 ? 14.497 -23.961 -11.629 1.00 27.58 ? 227 ALA A C 1 ATOM 1529 O O . ALA A 1 195 ? 15.720 -23.954 -11.856 1.00 24.28 ? 227 ALA A O 1 ATOM 1530 C CB . ALA A 1 195 ? 14.255 -21.841 -12.901 1.00 27.38 ? 227 ALA A CB 1 ATOM 1531 N N . ASN A 1 196 ? 13.908 -24.722 -10.701 1.00 28.57 ? 228 ASN A N 1 ATOM 1532 C CA . ASN A 1 196 ? 14.676 -25.564 -9.802 1.00 32.18 ? 228 ASN A CA 1 ATOM 1533 C C . ASN A 1 196 ? 15.877 -24.826 -9.196 1.00 33.16 ? 228 ASN A C 1 ATOM 1534 O O . ASN A 1 196 ? 17.017 -25.303 -9.197 1.00 33.85 ? 228 ASN A O 1 ATOM 1535 C CB . ASN A 1 196 ? 15.169 -26.788 -10.561 1.00 34.85 ? 228 ASN A CB 1 ATOM 1536 C CG . ASN A 1 196 ? 14.080 -27.454 -11.333 1.00 35.59 ? 228 ASN A CG 1 ATOM 1537 O OD1 . ASN A 1 196 ? 14.002 -27.303 -12.550 1.00 40.32 ? 228 ASN A OD1 1 ATOM 1538 N ND2 . ASN A 1 196 ? 13.211 -28.173 -10.634 1.00 36.03 ? 228 ASN A ND2 1 ATOM 1539 N N . GLN A 1 197 ? 15.626 -23.637 -8.693 1.00 34.26 ? 229 GLN A N 1 ATOM 1540 C CA . GLN A 1 197 ? 16.707 -22.823 -8.207 1.00 33.86 ? 229 GLN A CA 1 ATOM 1541 C C . GLN A 1 197 ? 17.070 -23.247 -6.799 1.00 35.46 ? 229 GLN A C 1 ATOM 1542 O O . GLN A 1 197 ? 18.252 -23.248 -6.435 1.00 34.97 ? 229 GLN A O 1 ATOM 1543 C CB . GLN A 1 197 ? 16.323 -21.360 -8.243 1.00 32.47 ? 229 GLN A CB 1 ATOM 1544 C CG . GLN A 1 197 ? 17.428 -20.470 -7.732 1.00 31.80 ? 229 GLN A CG 1 ATOM 1545 C CD . GLN A 1 197 ? 17.279 -19.055 -8.204 1.00 31.40 ? 229 GLN A CD 1 ATOM 1546 O OE1 . GLN A 1 197 ? 16.419 -18.314 -7.724 1.00 32.46 ? 229 GLN A OE1 1 ATOM 1547 N NE2 . GLN A 1 197 ? 18.108 -18.668 -9.150 1.00 30.04 ? 229 GLN A NE2 1 ATOM 1548 N N . PHE A 1 198 ? 16.053 -23.606 -6.016 1.00 37.30 ? 230 PHE A N 1 ATOM 1549 C CA . PHE A 1 198 ? 16.277 -24.087 -4.670 1.00 39.10 ? 230 PHE A CA 1 ATOM 1550 C C . PHE A 1 198 ? 17.073 -25.375 -4.738 1.00 41.80 ? 230 PHE A C 1 ATOM 1551 O O . PHE A 1 198 ? 18.056 -25.538 -4.006 1.00 45.78 ? 230 PHE A O 1 ATOM 1552 C CB . PHE A 1 198 ? 14.960 -24.315 -3.942 1.00 39.98 ? 230 PHE A CB 1 ATOM 1553 C CG . PHE A 1 198 ? 14.109 -23.083 -3.841 1.00 42.19 ? 230 PHE A CG 1 ATOM 1554 C CD1 . PHE A 1 198 ? 14.651 -21.882 -3.392 1.00 43.53 ? 230 PHE A CD1 1 ATOM 1555 C CD2 . PHE A 1 198 ? 12.767 -23.114 -4.189 1.00 42.77 ? 230 PHE A CD2 1 ATOM 1556 C CE1 . PHE A 1 198 ? 13.877 -20.734 -3.306 1.00 43.22 ? 230 PHE A CE1 1 ATOM 1557 C CE2 . PHE A 1 198 ? 11.986 -21.972 -4.099 1.00 42.91 ? 230 PHE A CE2 1 ATOM 1558 C CZ . PHE A 1 198 ? 12.541 -20.780 -3.655 1.00 43.25 ? 230 PHE A CZ 1 ATOM 1559 N N . GLU A 1 199 ? 16.675 -26.268 -5.639 1.00 40.80 ? 231 GLU A N 1 ATOM 1560 C CA . GLU A 1 199 ? 17.341 -27.553 -5.774 1.00 41.74 ? 231 GLU A CA 1 ATOM 1561 C C . GLU A 1 199 ? 18.809 -27.338 -6.107 1.00 36.52 ? 231 GLU A C 1 ATOM 1562 O O . GLU A 1 199 ? 19.701 -27.884 -5.465 1.00 33.68 ? 231 GLU A O 1 ATOM 1563 C CB . GLU A 1 199 ? 16.655 -28.370 -6.864 1.00 51.40 ? 231 GLU A CB 1 ATOM 1564 C CG . GLU A 1 199 ? 16.843 -29.880 -6.751 1.00 60.19 ? 231 GLU A CG 1 ATOM 1565 C CD . GLU A 1 199 ? 16.468 -30.629 -8.033 1.00 63.52 ? 231 GLU A CD 1 ATOM 1566 O OE1 . GLU A 1 199 ? 15.669 -30.107 -8.853 1.00 62.21 ? 231 GLU A OE1 1 ATOM 1567 O OE2 . GLU A 1 199 ? 16.985 -31.753 -8.218 1.00 65.93 -1 231 GLU A OE2 1 ATOM 1568 N N . TRP A 1 200 ? 19.043 -26.511 -7.111 1.00 34.84 ? 232 TRP A N 1 ATOM 1569 C CA . TRP A 1 200 ? 20.388 -26.144 -7.536 1.00 34.66 ? 232 TRP A CA 1 ATOM 1570 C C . TRP A 1 200 ? 21.184 -25.412 -6.453 1.00 34.89 ? 232 TRP A C 1 ATOM 1571 O O . TRP A 1 200 ? 22.393 -25.605 -6.338 1.00 34.68 ? 232 TRP A O 1 ATOM 1572 C CB . TRP A 1 200 ? 20.286 -25.256 -8.774 1.00 34.64 ? 232 TRP A CB 1 ATOM 1573 C CG . TRP A 1 200 ? 21.580 -24.769 -9.305 1.00 34.40 ? 232 TRP A CG 1 ATOM 1574 C CD1 . TRP A 1 200 ? 22.378 -25.405 -10.176 1.00 35.02 ? 232 TRP A CD1 1 ATOM 1575 C CD2 . TRP A 1 200 ? 22.208 -23.526 -9.017 1.00 35.51 ? 232 TRP A CD2 1 ATOM 1576 N NE1 . TRP A 1 200 ? 23.480 -24.645 -10.465 1.00 35.87 ? 232 TRP A NE1 1 ATOM 1577 C CE2 . TRP A 1 200 ? 23.408 -23.485 -9.755 1.00 36.34 ? 232 TRP A CE2 1 ATOM 1578 C CE3 . TRP A 1 200 ? 21.879 -22.446 -8.210 1.00 36.51 ? 232 TRP A CE3 1 ATOM 1579 C CZ2 . TRP A 1 200 ? 24.290 -22.405 -9.712 1.00 38.03 ? 232 TRP A CZ2 1 ATOM 1580 C CZ3 . TRP A 1 200 ? 22.747 -21.360 -8.180 1.00 39.11 ? 232 TRP A CZ3 1 ATOM 1581 C CH2 . TRP A 1 200 ? 23.943 -21.350 -8.931 1.00 38.11 ? 232 TRP A CH2 1 ATOM 1582 N N . LEU A 1 201 ? 20.519 -24.553 -5.683 1.00 34.69 ? 233 LEU A N 1 ATOM 1583 C CA . LEU A 1 201 ? 21.166 -23.848 -4.581 1.00 34.41 ? 233 LEU A CA 1 ATOM 1584 C C . LEU A 1 201 ? 21.610 -24.832 -3.522 1.00 34.96 ? 233 LEU A C 1 ATOM 1585 O O . LEU A 1 201 ? 22.809 -24.946 -3.248 1.00 35.80 ? 233 LEU A O 1 ATOM 1586 C CB . LEU A 1 201 ? 20.224 -22.818 -3.956 1.00 34.55 ? 233 LEU A CB 1 ATOM 1587 C CG . LEU A 1 201 ? 20.797 -21.912 -2.861 1.00 33.19 ? 233 LEU A CG 1 ATOM 1588 C CD1 . LEU A 1 201 ? 21.996 -21.131 -3.365 1.00 33.33 ? 233 LEU A CD1 1 ATOM 1589 C CD2 . LEU A 1 201 ? 19.709 -20.963 -2.411 1.00 32.85 ? 233 LEU A CD2 1 ATOM 1590 N N . GLU A 1 202 ? 20.643 -25.541 -2.937 1.00 35.22 ? 234 GLU A N 1 ATOM 1591 C CA . GLU A 1 202 ? 20.937 -26.605 -1.978 1.00 36.38 ? 234 GLU A CA 1 ATOM 1592 C C . GLU A 1 202 ? 22.064 -27.467 -2.486 1.00 36.43 ? 234 GLU A C 1 ATOM 1593 O O . GLU A 1 202 ? 23.034 -27.716 -1.765 1.00 37.60 ? 234 GLU A O 1 ATOM 1594 C CB . GLU A 1 202 ? 19.717 -27.480 -1.738 1.00 37.67 ? 234 GLU A CB 1 ATOM 1595 C CG . GLU A 1 202 ? 18.951 -27.115 -0.487 1.00 41.16 ? 234 GLU A CG 1 ATOM 1596 C CD . GLU A 1 202 ? 17.457 -27.362 -0.601 1.00 44.61 ? 234 GLU A CD 1 ATOM 1597 O OE1 . GLU A 1 202 ? 16.952 -27.405 -1.753 1.00 41.83 ? 234 GLU A OE1 1 ATOM 1598 O OE2 . GLU A 1 202 ? 16.793 -27.486 0.474 1.00 48.35 -1 234 GLU A OE2 1 ATOM 1599 N N . SER A 1 203 ? 21.932 -27.908 -3.735 1.00 35.95 ? 235 SER A N 1 ATOM 1600 C CA . SER A 1 203 ? 23.001 -28.636 -4.396 1.00 36.71 ? 235 SER A CA 1 ATOM 1601 C C . SER A 1 203 ? 24.335 -27.845 -4.438 1.00 37.61 ? 235 SER A C 1 ATOM 1602 O O . SER A 1 203 ? 25.335 -28.319 -3.892 1.00 39.10 ? 235 SER A O 1 ATOM 1603 C CB . SER A 1 203 ? 22.574 -29.061 -5.793 1.00 35.40 ? 235 SER A CB 1 ATOM 1604 O OG . SER A 1 203 ? 23.594 -29.818 -6.398 1.00 34.09 ? 235 SER A OG 1 ATOM 1605 N N . THR A 1 204 ? 24.354 -26.655 -5.046 1.00 36.98 ? 236 THR A N 1 ATOM 1606 C CA . THR A 1 204 ? 25.601 -25.897 -5.181 1.00 38.02 ? 236 THR A CA 1 ATOM 1607 C C . THR A 1 204 ? 26.264 -25.602 -3.820 1.00 40.67 ? 236 THR A C 1 ATOM 1608 O O . THR A 1 204 ? 27.505 -25.558 -3.722 1.00 42.41 ? 236 THR A O 1 ATOM 1609 C CB . THR A 1 204 ? 25.419 -24.568 -5.949 1.00 38.05 ? 236 THR A CB 1 ATOM 1610 O OG1 . THR A 1 204 ? 24.755 -24.794 -7.204 1.00 37.97 ? 236 THR A OG1 1 ATOM 1611 C CG2 . THR A 1 204 ? 26.778 -23.916 -6.220 1.00 37.42 ? 236 THR A CG2 1 ATOM 1612 N N . LEU A 1 205 ? 25.459 -25.400 -2.776 1.00 40.72 ? 237 LEU A N 1 ATOM 1613 C CA . LEU A 1 205 ? 26.020 -25.085 -1.459 1.00 41.33 ? 237 LEU A CA 1 ATOM 1614 C C . LEU A 1 205 ? 26.685 -26.311 -0.877 1.00 43.14 ? 237 LEU A C 1 ATOM 1615 O O . LEU A 1 205 ? 27.883 -26.276 -0.587 1.00 44.45 ? 237 LEU A O 1 ATOM 1616 C CB . LEU A 1 205 ? 24.956 -24.535 -0.499 1.00 39.70 ? 237 LEU A CB 1 ATOM 1617 C CG . LEU A 1 205 ? 24.511 -23.101 -0.806 1.00 37.67 ? 237 LEU A CG 1 ATOM 1618 C CD1 . LEU A 1 205 ? 23.244 -22.794 -0.029 1.00 37.80 ? 237 LEU A CD1 1 ATOM 1619 C CD2 . LEU A 1 205 ? 25.600 -22.069 -0.522 1.00 36.45 ? 237 LEU A CD2 1 ATOM 1620 N N . ASN A 1 206 ? 25.901 -27.385 -0.741 1.00 44.65 ? 238 ASN A N 1 ATOM 1621 C CA . ASN A 1 206 ? 26.381 -28.691 -0.270 1.00 45.17 ? 238 ASN A CA 1 ATOM 1622 C C . ASN A 1 206 ? 27.720 -29.053 -0.898 1.00 45.45 ? 238 ASN A C 1 ATOM 1623 O O . ASN A 1 206 ? 28.679 -29.445 -0.211 1.00 47.13 ? 238 ASN A O 1 ATOM 1624 C CB . ASN A 1 206 ? 25.334 -29.768 -0.573 1.00 44.47 ? 238 ASN A CB 1 ATOM 1625 C CG . ASN A 1 206 ? 25.600 -31.098 0.130 1.00 46.96 ? 238 ASN A CG 1 ATOM 1626 O OD1 . ASN A 1 206 ? 25.163 -32.138 -0.364 1.00 54.32 ? 238 ASN A OD1 1 ATOM 1627 N ND2 . ASN A 1 206 ? 26.269 -31.084 1.285 1.00 45.73 ? 238 ASN A ND2 1 ATOM 1628 N N . ASN A 1 207 ? 27.790 -28.871 -2.207 1.00 44.39 ? 239 ASN A N 1 ATOM 1629 C CA . ASN A 1 207 ? 29.032 -29.045 -2.931 1.00 45.17 ? 239 ASN A CA 1 ATOM 1630 C C . ASN A 1 207 ? 30.186 -28.131 -2.408 1.00 43.41 ? 239 ASN A C 1 ATOM 1631 O O . ASN A 1 207 ? 31.277 -28.607 -2.152 1.00 43.90 ? 239 ASN A O 1 ATOM 1632 C CB . ASN A 1 207 ? 28.752 -28.939 -4.439 1.00 46.59 ? 239 ASN A CB 1 ATOM 1633 C CG . ASN A 1 207 ? 29.984 -28.637 -5.256 1.00 51.72 ? 239 ASN A CG 1 ATOM 1634 O OD1 . ASN A 1 207 ? 30.012 -27.650 -5.987 1.00 61.98 ? 239 ASN A OD1 1 ATOM 1635 N ND2 . ASN A 1 207 ? 31.005 -29.480 -5.152 1.00 53.16 ? 239 ASN A ND2 1 ATOM 1636 N N . SER A 1 208 ? 29.958 -26.847 -2.191 1.00 44.63 ? 240 SER A N 1 ATOM 1637 C CA . SER A 1 208 ? 31.042 -25.986 -1.689 1.00 45.23 ? 240 SER A CA 1 ATOM 1638 C C . SER A 1 208 ? 31.427 -26.368 -0.261 1.00 47.02 ? 240 SER A C 1 ATOM 1639 O O . SER A 1 208 ? 32.593 -26.195 0.159 1.00 44.16 ? 240 SER A O 1 ATOM 1640 C CB . SER A 1 208 ? 30.636 -24.510 -1.742 1.00 44.47 ? 240 SER A CB 1 ATOM 1641 O OG . SER A 1 208 ? 30.518 -24.054 -3.077 1.00 42.79 ? 240 SER A OG 1 ATOM 1642 N N . GLN A 1 209 ? 30.432 -26.878 0.472 1.00 51.05 ? 241 GLN A N 1 ATOM 1643 C CA . GLN A 1 209 ? 30.580 -27.240 1.881 1.00 54.56 ? 241 GLN A CA 1 ATOM 1644 C C . GLN A 1 209 ? 31.744 -28.155 2.006 1.00 56.67 ? 241 GLN A C 1 ATOM 1645 O O . GLN A 1 209 ? 32.630 -27.929 2.820 1.00 57.30 ? 241 GLN A O 1 ATOM 1646 C CB . GLN A 1 209 ? 29.334 -27.943 2.421 1.00 54.92 ? 241 GLN A CB 1 ATOM 1647 C CG . GLN A 1 209 ? 29.379 -28.218 3.914 1.00 57.23 ? 241 GLN A CG 1 ATOM 1648 C CD . GLN A 1 209 ? 28.062 -27.875 4.608 1.00 60.38 ? 241 GLN A CD 1 ATOM 1649 O OE1 . GLN A 1 209 ? 27.719 -26.704 4.741 1.00 58.66 ? 241 GLN A OE1 1 ATOM 1650 N NE2 . GLN A 1 209 ? 27.324 -28.894 5.062 1.00 61.10 ? 241 GLN A NE2 1 ATOM 1651 N N . GLN A 1 210 ? 31.753 -29.168 1.151 1.00 60.60 ? 242 GLN A N 1 ATOM 1652 C CA . GLN A 1 210 ? 32.778 -30.187 1.207 1.00 63.44 ? 242 GLN A CA 1 ATOM 1653 C C . GLN A 1 210 ? 34.137 -29.773 0.678 1.00 63.09 ? 242 GLN A C 1 ATOM 1654 O O . GLN A 1 210 ? 35.148 -30.210 1.207 1.00 78.57 ? 242 GLN A O 1 ATOM 1655 C CB . GLN A 1 210 ? 32.295 -31.422 0.485 1.00 62.78 ? 242 GLN A CB 1 ATOM 1656 C CG . GLN A 1 210 ? 31.219 -32.119 1.283 1.00 65.45 ? 242 GLN A CG 1 ATOM 1657 C CD . GLN A 1 210 ? 30.066 -32.535 0.424 1.00 68.72 ? 242 GLN A CD 1 ATOM 1658 O OE1 . GLN A 1 210 ? 30.201 -32.637 -0.790 1.00 67.72 ? 242 GLN A OE1 1 ATOM 1659 N NE2 . GLN A 1 210 ? 28.917 -32.778 1.046 1.00 73.77 ? 242 GLN A NE2 1 ATOM 1660 N N . ASN A 1 211 ? 34.184 -28.911 -0.325 1.00 57.80 ? 243 ASN A N 1 ATOM 1661 C CA . ASN A 1 211 ? 35.447 -28.641 -1.003 1.00 57.22 ? 243 ASN A CA 1 ATOM 1662 C C . ASN A 1 211 ? 36.228 -27.462 -0.401 1.00 61.89 ? 243 ASN A C 1 ATOM 1663 O O . ASN A 1 211 ? 37.013 -26.799 -1.109 1.00 57.12 ? 243 ASN A O 1 ATOM 1664 C CB . ASN A 1 211 ? 35.189 -28.449 -2.500 1.00 55.21 ? 243 ASN A CB 1 ATOM 1665 C CG . ASN A 1 211 ? 34.175 -29.440 -3.031 1.00 50.10 ? 243 ASN A CG 1 ATOM 1666 O OD1 . ASN A 1 211 ? 33.560 -30.166 -2.253 1.00 47.93 ? 243 ASN A OD1 1 ATOM 1667 N ND2 . ASN A 1 211 ? 33.996 -29.482 -4.343 1.00 46.79 ? 243 ASN A ND2 1 ATOM 1668 N N . LYS A 1 212 ? 36.049 -27.243 0.910 1.00 66.69 ? 244 LYS A N 1 ATOM 1669 C CA . LYS A 1 212 ? 36.666 -26.119 1.610 1.00 72.25 ? 244 LYS A CA 1 ATOM 1670 C C . LYS A 1 212 ? 36.477 -24.862 0.768 1.00 69.46 ? 244 LYS A C 1 ATOM 1671 O O . LYS A 1 212 ? 37.451 -24.210 0.375 1.00 68.31 ? 244 LYS A O 1 ATOM 1672 C CB . LYS A 1 212 ? 38.165 -26.358 1.865 1.00 79.08 ? 244 LYS A CB 1 ATOM 1673 C CG . LYS A 1 212 ? 38.527 -27.599 2.678 1.00 86.91 ? 244 LYS A CG 1 ATOM 1674 C CD . LYS A 1 212 ? 39.884 -27.412 3.369 1.00 97.14 ? 244 LYS A CD 1 ATOM 1675 C CE . LYS A 1 212 ? 40.557 -28.720 3.787 1.00 101.06 ? 244 LYS A CE 1 ATOM 1676 N NZ . LYS A 1 212 ? 41.481 -29.256 2.741 1.00 103.76 1 244 LYS A NZ 1 ATOM 1677 N N . GLU A 1 213 ? 35.224 -24.553 0.445 1.00 64.22 ? 245 GLU A N 1 ATOM 1678 C CA . GLU A 1 213 ? 34.938 -23.377 -0.368 1.00 60.33 ? 245 GLU A CA 1 ATOM 1679 C C . GLU A 1 213 ? 34.041 -22.378 0.354 1.00 54.39 ? 245 GLU A C 1 ATOM 1680 O O . GLU A 1 213 ? 33.076 -22.764 1.014 1.00 49.29 ? 245 GLU A O 1 ATOM 1681 C CB . GLU A 1 213 ? 34.334 -23.782 -1.717 1.00 61.37 ? 245 GLU A CB 1 ATOM 1682 C CG . GLU A 1 213 ? 35.378 -23.831 -2.828 1.00 63.86 ? 245 GLU A CG 1 ATOM 1683 C CD . GLU A 1 213 ? 34.790 -23.722 -4.225 1.00 63.72 ? 245 GLU A CD 1 ATOM 1684 O OE1 . GLU A 1 213 ? 33.662 -24.228 -4.446 1.00 59.37 ? 245 GLU A OE1 1 ATOM 1685 O OE2 . GLU A 1 213 ? 35.471 -23.131 -5.096 1.00 62.37 -1 245 GLU A OE2 1 ATOM 1686 N N . LYS A 1 214 ? 34.384 -21.094 0.228 1.00 47.98 ? 246 LYS A N 1 ATOM 1687 C CA . LYS A 1 214 ? 33.524 -20.022 0.710 1.00 45.13 ? 246 LYS A CA 1 ATOM 1688 C C . LYS A 1 214 ? 32.680 -19.386 -0.414 1.00 40.99 ? 246 LYS A C 1 ATOM 1689 O O . LYS A 1 214 ? 33.122 -19.195 -1.566 1.00 36.00 ? 246 LYS A O 1 ATOM 1690 C CB . LYS A 1 214 ? 34.334 -18.958 1.446 1.00 46.40 ? 246 LYS A CB 1 ATOM 1691 C CG . LYS A 1 214 ? 35.183 -19.504 2.578 1.00 48.68 ? 246 LYS A CG 1 ATOM 1692 C CD . LYS A 1 214 ? 34.357 -20.073 3.729 1.00 49.60 ? 246 LYS A CD 1 ATOM 1693 C CE . LYS A 1 214 ? 34.142 -19.040 4.819 1.00 51.57 ? 246 LYS A CE 1 ATOM 1694 N NZ . LYS A 1 214 ? 33.178 -19.513 5.849 1.00 52.13 1 246 LYS A NZ 1 ATOM 1695 N N . VAL A 1 215 ? 31.451 -19.064 -0.026 1.00 37.88 ? 247 VAL A N 1 ATOM 1696 C CA . VAL A 1 215 ? 30.445 -18.551 -0.916 1.00 35.48 ? 247 VAL A CA 1 ATOM 1697 C C . VAL A 1 215 ? 30.020 -17.159 -0.499 1.00 31.92 ? 247 VAL A C 1 ATOM 1698 O O . VAL A 1 215 ? 29.769 -16.897 0.673 1.00 31.35 ? 247 VAL A O 1 ATOM 1699 C CB . VAL A 1 215 ? 29.192 -19.441 -0.895 1.00 36.86 ? 247 VAL A CB 1 ATOM 1700 C CG1 . VAL A 1 215 ? 27.953 -18.674 -1.368 1.00 37.54 ? 247 VAL A CG1 1 ATOM 1701 C CG2 . VAL A 1 215 ? 29.418 -20.669 -1.756 1.00 37.35 ? 247 VAL A CG2 1 ATOM 1702 N N . TYR A 1 216 ? 29.924 -16.294 -1.503 1.00 28.33 ? 248 TYR A N 1 ATOM 1703 C CA . TYR A 1 216 ? 29.239 -15.007 -1.428 1.00 25.04 ? 248 TYR A CA 1 ATOM 1704 C C . TYR A 1 216 ? 27.953 -15.062 -2.249 1.00 23.15 ? 248 TYR A C 1 ATOM 1705 O O . TYR A 1 216 ? 28.020 -15.276 -3.457 1.00 24.94 ? 248 TYR A O 1 ATOM 1706 C CB . TYR A 1 216 ? 30.130 -13.930 -2.041 1.00 23.29 ? 248 TYR A CB 1 ATOM 1707 C CG . TYR A 1 216 ? 31.284 -13.480 -1.203 1.00 22.13 ? 248 TYR A CG 1 ATOM 1708 C CD1 . TYR A 1 216 ? 31.437 -13.886 0.124 1.00 21.49 ? 248 TYR A CD1 1 ATOM 1709 C CD2 . TYR A 1 216 ? 32.200 -12.587 -1.728 1.00 21.79 ? 248 TYR A CD2 1 ATOM 1710 C CE1 . TYR A 1 216 ? 32.498 -13.427 0.876 1.00 21.72 ? 248 TYR A CE1 1 ATOM 1711 C CE2 . TYR A 1 216 ? 33.254 -12.109 -0.978 1.00 21.79 ? 248 TYR A CE2 1 ATOM 1712 C CZ . TYR A 1 216 ? 33.398 -12.535 0.316 1.00 21.94 ? 248 TYR A CZ 1 ATOM 1713 O OH . TYR A 1 216 ? 34.448 -12.054 1.048 1.00 23.23 ? 248 TYR A OH 1 ATOM 1714 N N . ILE A 1 217 ? 26.794 -14.845 -1.640 1.00 20.40 ? 249 ILE A N 1 ATOM 1715 C CA . ILE A 1 217 ? 25.576 -14.761 -2.433 1.00 18.92 ? 249 ILE A CA 1 ATOM 1716 C C . ILE A 1 217 ? 25.374 -13.388 -3.045 1.00 18.44 ? 249 ILE A C 1 ATOM 1717 O O . ILE A 1 217 ? 25.489 -12.373 -2.363 1.00 18.90 ? 249 ILE A O 1 ATOM 1718 C CB . ILE A 1 217 ? 24.329 -14.991 -1.623 1.00 18.85 ? 249 ILE A CB 1 ATOM 1719 C CG1 . ILE A 1 217 ? 24.407 -16.276 -0.808 1.00 19.22 ? 249 ILE A CG1 1 ATOM 1720 C CG2 . ILE A 1 217 ? 23.154 -14.994 -2.556 1.00 19.27 ? 249 ILE A CG2 1 ATOM 1721 C CD1 . ILE A 1 217 ? 24.754 -17.504 -1.585 1.00 19.68 ? 249 ILE A CD1 1 ATOM 1722 N N . ILE A 1 218 ? 25.037 -13.376 -4.327 1.00 17.43 ? 250 ILE A N 1 ATOM 1723 C CA . ILE A 1 218 ? 24.743 -12.172 -5.090 1.00 17.02 ? 250 ILE A CA 1 ATOM 1724 C C . ILE A 1 218 ? 23.306 -12.351 -5.575 1.00 16.98 ? 250 ILE A C 1 ATOM 1725 O O . ILE A 1 218 ? 22.892 -13.457 -5.906 1.00 17.11 ? 250 ILE A O 1 ATOM 1726 C CB . ILE A 1 218 ? 25.773 -12.054 -6.236 1.00 17.19 ? 250 ILE A CB 1 ATOM 1727 C CG1 . ILE A 1 218 ? 26.799 -11.032 -5.872 1.00 17.94 ? 250 ILE A CG1 1 ATOM 1728 C CG2 . ILE A 1 218 ? 25.206 -11.620 -7.568 1.00 17.09 ? 250 ILE A CG2 1 ATOM 1729 C CD1 . ILE A 1 218 ? 27.494 -11.353 -4.579 1.00 18.57 ? 250 ILE A CD1 1 ATOM 1730 N N . ALA A 1 219 ? 22.518 -11.292 -5.568 1.00 16.51 ? 251 ALA A N 1 ATOM 1731 C CA . ALA A 1 219 ? 21.158 -11.366 -6.104 1.00 16.24 ? 251 ALA A CA 1 ATOM 1732 C C . ALA A 1 219 ? 20.552 -9.982 -6.091 1.00 16.31 ? 251 ALA A C 1 ATOM 1733 O O . ALA A 1 219 ? 21.094 -9.063 -5.469 1.00 16.86 ? 251 ALA A O 1 ATOM 1734 C CB . ALA A 1 219 ? 20.291 -12.324 -5.298 1.00 16.01 ? 251 ALA A CB 1 ATOM 1735 N N . HIS A 1 220 ? 19.413 -9.837 -6.753 1.00 15.94 ? 252 HIS A N 1 ATOM 1736 C CA . HIS A 1 220 ? 18.781 -8.531 -6.884 1.00 15.34 ? 252 HIS A CA 1 ATOM 1737 C C . HIS A 1 220 ? 17.757 -8.266 -5.782 1.00 15.15 ? 252 HIS A C 1 ATOM 1738 O O . HIS A 1 220 ? 17.925 -7.334 -4.978 1.00 15.09 ? 252 HIS A O 1 ATOM 1739 C CB . HIS A 1 220 ? 18.112 -8.419 -8.238 1.00 15.04 ? 252 HIS A CB 1 ATOM 1740 C CG . HIS A 1 220 ? 17.420 -7.124 -8.447 1.00 14.73 ? 252 HIS A CG 1 ATOM 1741 N ND1 . HIS A 1 220 ? 18.111 -5.960 -8.664 1.00 14.72 ? 252 HIS A ND1 1 ATOM 1742 C CD2 . HIS A 1 220 ? 16.109 -6.795 -8.451 1.00 14.65 ? 252 HIS A CD2 1 ATOM 1743 C CE1 . HIS A 1 220 ? 17.256 -4.968 -8.819 1.00 14.58 ? 252 HIS A CE1 1 ATOM 1744 N NE2 . HIS A 1 220 ? 16.035 -5.450 -8.697 1.00 14.61 ? 252 HIS A NE2 1 ATOM 1745 N N . VAL A 1 221 ? 16.694 -9.068 -5.759 1.00 14.50 ? 253 VAL A N 1 ATOM 1746 C CA . VAL A 1 221 ? 15.643 -8.864 -4.782 1.00 14.54 ? 253 VAL A CA 1 ATOM 1747 C C . VAL A 1 221 ? 16.160 -9.492 -3.515 1.00 14.47 ? 253 VAL A C 1 ATOM 1748 O O . VAL A 1 221 ? 16.437 -10.686 -3.500 1.00 15.31 ? 253 VAL A O 1 ATOM 1749 C CB . VAL A 1 221 ? 14.317 -9.555 -5.174 1.00 14.62 ? 253 VAL A CB 1 ATOM 1750 C CG1 . VAL A 1 221 ? 13.218 -9.289 -4.147 1.00 14.43 ? 253 VAL A CG1 1 ATOM 1751 C CG2 . VAL A 1 221 ? 13.857 -9.075 -6.532 1.00 14.86 ? 253 VAL A CG2 1 ATOM 1752 N N . PRO A 1 222 ? 16.288 -8.712 -2.446 1.00 13.96 ? 254 PRO A N 1 ATOM 1753 C CA . PRO A 1 222 ? 16.722 -9.331 -1.231 1.00 14.19 ? 254 PRO A CA 1 ATOM 1754 C C . PRO A 1 222 ? 15.650 -10.216 -0.561 1.00 14.55 ? 254 PRO A C 1 ATOM 1755 O O . PRO A 1 222 ? 14.453 -10.128 -0.842 1.00 13.64 ? 254 PRO A O 1 ATOM 1756 C CB . PRO A 1 222 ? 17.028 -8.135 -0.352 1.00 14.14 ? 254 PRO A CB 1 ATOM 1757 C CG . PRO A 1 222 ? 16.008 -7.136 -0.751 1.00 14.00 ? 254 PRO A CG 1 ATOM 1758 C CD . PRO A 1 222 ? 15.821 -7.341 -2.219 1.00 13.96 ? 254 PRO A CD 1 ATOM 1759 N N . VAL A 1 223 ? 16.138 -11.076 0.317 1.00 15.29 ? 255 VAL A N 1 ATOM 1760 C CA . VAL A 1 223 ? 15.316 -11.765 1.278 1.00 16.01 ? 255 VAL A CA 1 ATOM 1761 C C . VAL A 1 223 ? 14.942 -10.793 2.376 1.00 16.95 ? 255 VAL A C 1 ATOM 1762 O O . VAL A 1 223 ? 15.519 -9.703 2.498 1.00 17.19 ? 255 VAL A O 1 ATOM 1763 C CB . VAL A 1 223 ? 16.074 -12.931 1.934 1.00 16.14 ? 255 VAL A CB 1 ATOM 1764 C CG1 . VAL A 1 223 ? 16.547 -13.900 0.864 1.00 16.47 ? 255 VAL A CG1 1 ATOM 1765 C CG2 . VAL A 1 223 ? 17.252 -12.437 2.779 1.00 15.72 ? 255 VAL A CG2 1 ATOM 1766 N N . GLY A 1 224 ? 13.986 -11.215 3.193 1.00 17.87 ? 256 GLY A N 1 ATOM 1767 C CA . GLY A 1 224 ? 13.582 -10.451 4.365 1.00 17.87 ? 256 GLY A CA 1 ATOM 1768 C C . GLY A 1 224 ? 12.473 -9.449 4.137 1.00 17.55 ? 256 GLY A C 1 ATOM 1769 O O . GLY A 1 224 ? 11.812 -9.407 3.086 1.00 17.45 ? 256 GLY A O 1 ATOM 1770 N N . TYR A 1 225 ? 12.287 -8.631 5.156 1.00 16.83 ? 257 TYR A N 1 ATOM 1771 C CA . TYR A 1 225 ? 11.238 -7.663 5.159 1.00 16.27 ? 257 TYR A CA 1 ATOM 1772 C C . TYR A 1 225 ? 11.725 -6.307 4.672 1.00 15.80 ? 257 TYR A C 1 ATOM 1773 O O . TYR A 1 225 ? 12.837 -5.869 4.982 1.00 15.78 ? 257 TYR A O 1 ATOM 1774 C CB . TYR A 1 225 ? 10.655 -7.611 6.561 1.00 16.70 ? 257 TYR A CB 1 ATOM 1775 C CG . TYR A 1 225 ? 9.780 -8.811 6.813 1.00 17.04 ? 257 TYR A CG 1 ATOM 1776 C CD1 . TYR A 1 225 ? 10.309 -10.016 7.255 1.00 17.09 ? 257 TYR A CD1 1 ATOM 1777 C CD2 . TYR A 1 225 ? 8.425 -8.740 6.546 1.00 17.76 ? 257 TYR A CD2 1 ATOM 1778 C CE1 . TYR A 1 225 ? 9.497 -11.109 7.451 1.00 17.77 ? 257 TYR A CE1 1 ATOM 1779 C CE2 . TYR A 1 225 ? 7.610 -9.820 6.719 1.00 18.42 ? 257 TYR A CE2 1 ATOM 1780 C CZ . TYR A 1 225 ? 8.146 -10.993 7.165 1.00 18.85 ? 257 TYR A CZ 1 ATOM 1781 O OH . TYR A 1 225 ? 7.251 -12.016 7.293 1.00 21.84 ? 257 TYR A OH 1 ATOM 1782 N N . LEU A 1 226 ? 10.890 -5.650 3.882 1.00 15.49 ? 258 LEU A N 1 ATOM 1783 C CA . LEU A 1 226 ? 11.184 -4.301 3.450 1.00 15.44 ? 258 LEU A CA 1 ATOM 1784 C C . LEU A 1 226 ? 11.133 -3.393 4.649 1.00 16.12 ? 258 LEU A C 1 ATOM 1785 O O . LEU A 1 226 ? 10.118 -3.345 5.342 1.00 16.87 ? 258 LEU A O 1 ATOM 1786 C CB . LEU A 1 226 ? 10.166 -3.838 2.441 1.00 14.89 ? 258 LEU A CB 1 ATOM 1787 C CG . LEU A 1 226 ? 10.168 -4.614 1.134 1.00 14.31 ? 258 LEU A CG 1 ATOM 1788 C CD1 . LEU A 1 226 ? 8.921 -4.182 0.391 1.00 14.16 ? 258 LEU A CD1 1 ATOM 1789 C CD2 . LEU A 1 226 ? 11.427 -4.361 0.318 1.00 14.12 ? 258 LEU A CD2 1 ATOM 1790 N N . PRO A 1 227 ? 12.216 -2.654 4.903 1.00 16.78 ? 259 PRO A N 1 ATOM 1791 C CA . PRO A 1 227 ? 12.282 -1.965 6.184 1.00 17.47 ? 259 PRO A CA 1 ATOM 1792 C C . PRO A 1 227 ? 11.353 -0.732 6.331 1.00 18.22 ? 259 PRO A C 1 ATOM 1793 O O . PRO A 1 227 ? 11.030 -0.339 7.458 1.00 18.47 ? 259 PRO A O 1 ATOM 1794 C CB . PRO A 1 227 ? 13.766 -1.569 6.281 1.00 17.05 ? 259 PRO A CB 1 ATOM 1795 C CG . PRO A 1 227 ? 14.284 -1.559 4.892 1.00 16.89 ? 259 PRO A CG 1 ATOM 1796 C CD . PRO A 1 227 ? 13.251 -2.169 3.978 1.00 17.05 ? 259 PRO A CD 1 ATOM 1797 N N A SER A 1 228 ? 10.947 -0.100 5.231 0.50 18.46 ? 260 SER A N 1 ATOM 1798 N N B SER A 1 228 ? 10.914 -0.192 5.194 0.50 18.57 ? 260 SER A N 1 ATOM 1799 C CA A SER A 1 228 ? 10.097 1.086 5.353 0.50 18.77 ? 260 SER A CA 1 ATOM 1800 C CA B SER A 1 228 ? 10.118 1.022 5.121 0.50 18.93 ? 260 SER A CA 1 ATOM 1801 C C A SER A 1 228 ? 8.601 0.771 5.256 0.50 19.75 ? 260 SER A C 1 ATOM 1802 C C B SER A 1 228 ? 8.608 0.769 5.264 0.50 19.87 ? 260 SER A C 1 ATOM 1803 O O A SER A 1 228 ? 7.804 1.646 4.915 0.50 19.60 ? 260 SER A O 1 ATOM 1804 O O B SER A 1 228 ? 7.807 1.689 5.083 0.50 19.68 ? 260 SER A O 1 ATOM 1805 C CB A SER A 1 228 ? 10.514 2.180 4.375 0.50 18.06 ? 260 SER A CB 1 ATOM 1806 C CB B SER A 1 228 ? 10.394 1.675 3.776 0.50 18.45 ? 260 SER A CB 1 ATOM 1807 O OG A SER A 1 228 ? 11.421 3.060 5.024 0.50 17.68 ? 260 SER A OG 1 ATOM 1808 O OG B SER A 1 228 ? 10.660 0.663 2.807 0.50 18.36 ? 260 SER A OG 1 ATOM 1809 N N . SER A 1 229 ? 8.220 -0.460 5.597 1.00 20.54 ? 261 SER A N 1 ATOM 1810 C CA . SER A 1 229 ? 6.814 -0.816 5.686 1.00 22.10 ? 261 SER A CA 1 ATOM 1811 C C . SER A 1 229 ? 6.591 -2.105 6.483 1.00 23.99 ? 261 SER A C 1 ATOM 1812 O O . SER A 1 229 ? 7.541 -2.819 6.811 1.00 24.49 ? 261 SER A O 1 ATOM 1813 C CB . SER A 1 229 ? 6.155 -0.878 4.285 1.00 22.02 ? 261 SER A CB 1 ATOM 1814 O OG . SER A 1 229 ? 6.917 -1.594 3.338 1.00 21.53 ? 261 SER A OG 1 ATOM 1815 N N . GLN A 1 230 ? 5.316 -2.371 6.772 1.00 25.72 ? 262 GLN A N 1 ATOM 1816 C CA . GLN A 1 230 ? 4.901 -3.324 7.777 1.00 27.18 ? 262 GLN A CA 1 ATOM 1817 C C . GLN A 1 230 ? 4.538 -4.712 7.227 1.00 25.87 ? 262 GLN A C 1 ATOM 1818 O O . GLN A 1 230 ? 3.681 -4.850 6.361 1.00 26.34 ? 262 GLN A O 1 ATOM 1819 C CB . GLN A 1 230 ? 3.715 -2.722 8.544 1.00 30.72 ? 262 GLN A CB 1 ATOM 1820 C CG . GLN A 1 230 ? 2.968 -3.714 9.448 1.00 34.50 ? 262 GLN A CG 1 ATOM 1821 C CD . GLN A 1 230 ? 2.085 -3.064 10.513 1.00 35.17 ? 262 GLN A CD 1 ATOM 1822 O OE1 . GLN A 1 230 ? 1.740 -3.717 11.520 1.00 36.23 ? 262 GLN A OE1 1 ATOM 1823 N NE2 . GLN A 1 230 ? 1.706 -1.790 10.299 1.00 32.93 ? 262 GLN A NE2 1 ATOM 1824 N N . ASN A 1 231 ? 5.201 -5.730 7.763 1.00 24.97 ? 263 ASN A N 1 ATOM 1825 C CA . ASN A 1 231 ? 4.928 -7.140 7.480 1.00 24.94 ? 263 ASN A CA 1 ATOM 1826 C C . ASN A 1 231 ? 4.918 -7.492 5.981 1.00 24.05 ? 263 ASN A C 1 ATOM 1827 O O . ASN A 1 231 ? 4.223 -8.412 5.572 1.00 25.08 ? 263 ASN A O 1 ATOM 1828 C CB . ASN A 1 231 ? 3.641 -7.589 8.194 1.00 26.10 ? 263 ASN A CB 1 ATOM 1829 C CG . ASN A 1 231 ? 3.436 -9.108 8.174 1.00 29.02 ? 263 ASN A CG 1 ATOM 1830 O OD1 . ASN A 1 231 ? 4.382 -9.889 8.287 1.00 28.73 ? 263 ASN A OD1 1 ATOM 1831 N ND2 . ASN A 1 231 ? 2.180 -9.530 7.973 1.00 34.38 ? 263 ASN A ND2 1 ATOM 1832 N N . ILE A 1 232 ? 5.724 -6.796 5.173 1.00 22.00 ? 264 ILE A N 1 ATOM 1833 C CA . ILE A 1 232 ? 5.848 -7.103 3.741 1.00 20.00 ? 264 ILE A CA 1 ATOM 1834 C C . ILE A 1 232 ? 7.238 -7.555 3.375 1.00 18.71 ? 264 ILE A C 1 ATOM 1835 O O . ILE A 1 232 ? 8.157 -6.748 3.317 1.00 17.94 ? 264 ILE A O 1 ATOM 1836 C CB . ILE A 1 232 ? 5.577 -5.880 2.875 1.00 19.75 ? 264 ILE A CB 1 ATOM 1837 C CG1 . ILE A 1 232 ? 4.179 -5.357 3.161 1.00 20.44 ? 264 ILE A CG1 1 ATOM 1838 C CG2 . ILE A 1 232 ? 5.760 -6.211 1.397 1.00 19.07 ? 264 ILE A CG2 1 ATOM 1839 C CD1 . ILE A 1 232 ? 4.073 -3.859 2.956 1.00 21.18 ? 264 ILE A CD1 1 ATOM 1840 N N . THR A 1 233 ? 7.365 -8.843 3.092 1.00 18.05 ? 265 THR A N 1 ATOM 1841 C CA . THR A 1 233 ? 8.589 -9.400 2.572 1.00 18.27 ? 265 THR A CA 1 ATOM 1842 C C . THR A 1 233 ? 8.756 -8.867 1.178 1.00 18.18 ? 265 THR A C 1 ATOM 1843 O O . THR A 1 233 ? 7.770 -8.535 0.547 1.00 18.18 ? 265 THR A O 1 ATOM 1844 C CB . THR A 1 233 ? 8.487 -10.915 2.483 1.00 18.91 ? 265 THR A CB 1 ATOM 1845 O OG1 . THR A 1 233 ? 7.301 -11.245 1.754 1.00 19.09 ? 265 THR A OG1 1 ATOM 1846 C CG2 . THR A 1 233 ? 8.412 -11.535 3.887 1.00 19.57 ? 265 THR A CG2 1 ATOM 1847 N N . ALA A 1 234 ? 9.989 -8.792 0.694 1.00 18.41 ? 266 ALA A N 1 ATOM 1848 C CA . ALA A 1 234 ? 10.264 -8.207 -0.614 1.00 19.03 ? 266 ALA A CA 1 ATOM 1849 C C . ALA A 1 234 ? 9.919 -9.188 -1.725 1.00 20.41 ? 266 ALA A C 1 ATOM 1850 O O . ALA A 1 234 ? 9.258 -8.839 -2.715 1.00 21.66 ? 266 ALA A O 1 ATOM 1851 C CB . ALA A 1 234 ? 11.723 -7.814 -0.693 1.00 19.24 ? 266 ALA A CB 1 ATOM 1852 N N . MET A 1 235 ? 10.408 -10.412 -1.554 1.00 21.61 ? 267 MET A N 1 ATOM 1853 C CA . MET A 1 235 ? 9.945 -11.594 -2.284 1.00 22.13 ? 267 MET A CA 1 ATOM 1854 C C . MET A 1 235 ? 8.601 -12.033 -1.752 1.00 22.77 ? 267 MET A C 1 ATOM 1855 O O . MET A 1 235 ? 8.115 -11.508 -0.755 1.00 22.45 ? 267 MET A O 1 ATOM 1856 C CB . MET A 1 235 ? 10.877 -12.776 -2.014 1.00 22.52 ? 267 MET A CB 1 ATOM 1857 C CG . MET A 1 235 ? 12.250 -12.664 -2.639 1.00 23.26 ? 267 MET A CG 1 ATOM 1858 S SD . MET A 1 235 ? 13.438 -13.762 -1.855 1.00 23.13 ? 267 MET A SD 1 ATOM 1859 C CE . MET A 1 235 ? 12.387 -15.178 -1.607 1.00 23.00 ? 267 MET A CE 1 ATOM 1860 N N . ARG A 1 236 ? 8.031 -13.044 -2.394 1.00 24.30 ? 268 ARG A N 1 ATOM 1861 C CA . ARG A 1 236 ? 6.868 -13.736 -1.842 1.00 25.29 ? 268 ARG A CA 1 ATOM 1862 C C . ARG A 1 236 ? 7.252 -14.509 -0.582 1.00 26.84 ? 268 ARG A C 1 ATOM 1863 O O . ARG A 1 236 ? 8.169 -15.350 -0.582 1.00 24.55 ? 268 ARG A O 1 ATOM 1864 C CB . ARG A 1 236 ? 6.196 -14.651 -2.878 1.00 24.72 ? 268 ARG A CB 1 ATOM 1865 C CG . ARG A 1 236 ? 5.241 -13.919 -3.816 1.00 23.75 ? 268 ARG A CG 1 ATOM 1866 C CD . ARG A 1 236 ? 4.484 -14.862 -4.746 1.00 22.87 ? 268 ARG A CD 1 ATOM 1867 N NE . ARG A 1 236 ? 4.384 -14.306 -6.101 1.00 22.04 ? 268 ARG A NE 1 ATOM 1868 C CZ . ARG A 1 236 ? 4.782 -14.915 -7.218 1.00 22.02 ? 268 ARG A CZ 1 ATOM 1869 N NH1 . ARG A 1 236 ? 5.292 -16.159 -7.198 1.00 21.94 1 268 ARG A NH1 1 ATOM 1870 N NH2 . ARG A 1 236 ? 4.642 -14.276 -8.377 1.00 21.82 ? 268 ARG A NH2 1 ATOM 1871 N N . GLU A 1 237 ? 6.534 -14.175 0.486 1.00 30.10 ? 269 GLU A N 1 ATOM 1872 C CA . GLU A 1 237 ? 6.709 -14.779 1.788 1.00 34.54 ? 269 GLU A CA 1 ATOM 1873 C C . GLU A 1 237 ? 7.165 -16.203 1.628 1.00 35.95 ? 269 GLU A C 1 ATOM 1874 O O . GLU A 1 237 ? 8.160 -16.639 2.227 1.00 35.03 ? 269 GLU A O 1 ATOM 1875 C CB . GLU A 1 237 ? 5.368 -14.779 2.510 1.00 37.11 ? 269 GLU A CB 1 ATOM 1876 C CG . GLU A 1 237 ? 5.192 -15.862 3.574 1.00 40.07 ? 269 GLU A CG 1 ATOM 1877 C CD . GLU A 1 237 ? 5.177 -15.299 4.967 1.00 44.36 ? 269 GLU A CD 1 ATOM 1878 O OE1 . GLU A 1 237 ? 4.905 -14.084 5.113 1.00 50.70 ? 269 GLU A OE1 1 ATOM 1879 O OE2 . GLU A 1 237 ? 5.421 -16.076 5.913 1.00 48.24 -1 269 GLU A OE2 1 ATOM 1880 N N . TYR A 1 238 ? 6.405 -16.924 0.812 1.00 37.33 ? 270 TYR A N 1 ATOM 1881 C CA . TYR A 1 238 ? 6.590 -18.353 0.692 1.00 38.82 ? 270 TYR A CA 1 ATOM 1882 C C . TYR A 1 238 ? 8.026 -18.670 0.328 1.00 34.84 ? 270 TYR A C 1 ATOM 1883 O O . TYR A 1 238 ? 8.632 -19.568 0.904 1.00 33.81 ? 270 TYR A O 1 ATOM 1884 C CB . TYR A 1 238 ? 5.616 -18.956 -0.330 1.00 41.18 ? 270 TYR A CB 1 ATOM 1885 C CG . TYR A 1 238 ? 5.981 -20.368 -0.670 1.00 42.70 ? 270 TYR A CG 1 ATOM 1886 C CD1 . TYR A 1 238 ? 5.684 -21.416 0.200 1.00 44.14 ? 270 TYR A CD1 1 ATOM 1887 C CD2 . TYR A 1 238 ? 6.680 -20.648 -1.835 1.00 45.07 ? 270 TYR A CD2 1 ATOM 1888 C CE1 . TYR A 1 238 ? 6.047 -22.721 -0.106 1.00 47.55 ? 270 TYR A CE1 1 ATOM 1889 C CE2 . TYR A 1 238 ? 7.053 -21.943 -2.154 1.00 48.87 ? 270 TYR A CE2 1 ATOM 1890 C CZ . TYR A 1 238 ? 6.742 -22.985 -1.292 1.00 49.01 ? 270 TYR A CZ 1 ATOM 1891 O OH . TYR A 1 238 ? 7.144 -24.267 -1.634 1.00 48.27 ? 270 TYR A OH 1 ATOM 1892 N N . TYR A 1 239 ? 8.567 -17.922 -0.620 1.00 32.78 ? 271 TYR A N 1 ATOM 1893 C CA . TYR A 1 239 ? 9.924 -18.169 -1.053 1.00 32.78 ? 271 TYR A CA 1 ATOM 1894 C C . TYR A 1 239 ? 10.888 -17.650 -0.019 1.00 31.67 ? 271 TYR A C 1 ATOM 1895 O O . TYR A 1 239 ? 11.938 -18.268 0.214 1.00 30.54 ? 271 TYR A O 1 ATOM 1896 C CB . TYR A 1 239 ? 10.210 -17.505 -2.392 1.00 33.27 ? 271 TYR A CB 1 ATOM 1897 C CG . TYR A 1 239 ? 9.370 -18.030 -3.520 1.00 34.37 ? 271 TYR A CG 1 ATOM 1898 C CD1 . TYR A 1 239 ? 9.336 -19.389 -3.821 1.00 34.85 ? 271 TYR A CD1 1 ATOM 1899 C CD2 . TYR A 1 239 ? 8.605 -17.168 -4.291 1.00 34.47 ? 271 TYR A CD2 1 ATOM 1900 C CE1 . TYR A 1 239 ? 8.551 -19.872 -4.857 1.00 35.04 ? 271 TYR A CE1 1 ATOM 1901 C CE2 . TYR A 1 239 ? 7.835 -17.637 -5.338 1.00 35.68 ? 271 TYR A CE2 1 ATOM 1902 C CZ . TYR A 1 239 ? 7.807 -18.987 -5.618 1.00 35.32 ? 271 TYR A CZ 1 ATOM 1903 O OH . TYR A 1 239 ? 7.031 -19.439 -6.659 1.00 34.83 ? 271 TYR A OH 1 ATOM 1904 N N . ASN A 1 240 ? 10.549 -16.515 0.597 1.00 30.13 ? 272 ASN A N 1 ATOM 1905 C CA . ASN A 1 240 ? 11.462 -15.928 1.565 1.00 28.42 ? 272 ASN A CA 1 ATOM 1906 C C . ASN A 1 240 ? 11.726 -16.926 2.648 1.00 29.02 ? 272 ASN A C 1 ATOM 1907 O O . ASN A 1 240 ? 12.877 -17.161 2.982 1.00 29.54 ? 272 ASN A O 1 ATOM 1908 C CB . ASN A 1 240 ? 10.957 -14.619 2.155 1.00 26.83 ? 272 ASN A CB 1 ATOM 1909 C CG . ASN A 1 240 ? 11.846 -14.121 3.268 1.00 24.91 ? 272 ASN A CG 1 ATOM 1910 O OD1 . ASN A 1 240 ? 13.002 -13.763 3.051 1.00 22.40 ? 272 ASN A OD1 1 ATOM 1911 N ND2 . ASN A 1 240 ? 11.323 -14.142 4.476 1.00 25.32 ? 272 ASN A ND2 1 ATOM 1912 N N . GLU A 1 241 ? 10.667 -17.554 3.150 1.00 30.48 ? 273 GLU A N 1 ATOM 1913 C CA . GLU A 1 241 ? 10.807 -18.568 4.198 1.00 32.17 ? 273 GLU A CA 1 ATOM 1914 C C . GLU A 1 241 ? 11.689 -19.726 3.744 1.00 32.89 ? 273 GLU A C 1 ATOM 1915 O O . GLU A 1 241 ? 12.552 -20.207 4.482 1.00 34.75 ? 273 GLU A O 1 ATOM 1916 C CB . GLU A 1 241 ? 9.446 -19.105 4.598 1.00 32.52 ? 273 GLU A CB 1 ATOM 1917 C CG . GLU A 1 241 ? 8.565 -18.090 5.298 1.00 34.64 ? 273 GLU A CG 1 ATOM 1918 C CD . GLU A 1 241 ? 9.073 -17.677 6.671 1.00 37.28 ? 273 GLU A CD 1 ATOM 1919 O OE1 . GLU A 1 241 ? 9.678 -18.511 7.386 1.00 37.28 ? 273 GLU A OE1 1 ATOM 1920 O OE2 . GLU A 1 241 ? 8.847 -16.498 7.037 1.00 42.44 -1 273 GLU A OE2 1 ATOM 1921 N N . LYS A 1 242 ? 11.462 -20.149 2.513 1.00 32.02 ? 274 LYS A N 1 ATOM 1922 C CA . LYS A 1 242 ? 12.185 -21.250 1.925 1.00 32.34 ? 274 LYS A CA 1 ATOM 1923 C C . LYS A 1 242 ? 13.676 -20.924 1.809 1.00 29.47 ? 274 LYS A C 1 ATOM 1924 O O . LYS A 1 242 ? 14.524 -21.727 2.156 1.00 28.53 ? 274 LYS A O 1 ATOM 1925 C CB . LYS A 1 242 ? 11.581 -21.521 0.555 1.00 36.01 ? 274 LYS A CB 1 ATOM 1926 C CG . LYS A 1 242 ? 11.589 -22.966 0.097 1.00 40.21 ? 274 LYS A CG 1 ATOM 1927 C CD . LYS A 1 242 ? 10.363 -23.238 -0.778 1.00 43.42 ? 274 LYS A CD 1 ATOM 1928 C CE . LYS A 1 242 ? 10.538 -24.451 -1.685 1.00 45.84 ? 274 LYS A CE 1 ATOM 1929 N NZ . LYS A 1 242 ? 10.655 -25.722 -0.922 1.00 48.97 1 274 LYS A NZ 1 ATOM 1930 N N . LEU A 1 243 ? 13.988 -19.731 1.330 1.00 28.15 ? 275 LEU A N 1 ATOM 1931 C CA . LEU A 1 243 ? 15.381 -19.306 1.164 1.00 27.24 ? 275 LEU A CA 1 ATOM 1932 C C . LEU A 1 243 ? 16.132 -19.143 2.469 1.00 28.41 ? 275 LEU A C 1 ATOM 1933 O O . LEU A 1 243 ? 17.346 -19.409 2.528 1.00 26.37 ? 275 LEU A O 1 ATOM 1934 C CB . LEU A 1 243 ? 15.444 -17.955 0.472 1.00 26.15 ? 275 LEU A CB 1 ATOM 1935 C CG . LEU A 1 243 ? 15.577 -17.905 -1.030 1.00 25.23 ? 275 LEU A CG 1 ATOM 1936 C CD1 . LEU A 1 243 ? 15.737 -16.451 -1.475 1.00 25.21 ? 275 LEU A CD1 1 ATOM 1937 C CD2 . LEU A 1 243 ? 16.781 -18.717 -1.442 1.00 24.73 ? 275 LEU A CD2 1 ATOM 1938 N N . ILE A 1 244 ? 15.415 -18.639 3.481 1.00 29.83 ? 276 ILE A N 1 ATOM 1939 C CA . ILE A 1 244 ? 16.000 -18.327 4.781 1.00 30.50 ? 276 ILE A CA 1 ATOM 1940 C C . ILE A 1 244 ? 16.479 -19.628 5.378 1.00 32.99 ? 276 ILE A C 1 ATOM 1941 O O . ILE A 1 244 ? 17.614 -19.702 5.872 1.00 32.12 ? 276 ILE A O 1 ATOM 1942 C CB . ILE A 1 244 ? 14.986 -17.641 5.722 1.00 29.99 ? 276 ILE A CB 1 ATOM 1943 C CG1 . ILE A 1 244 ? 14.746 -16.192 5.312 1.00 30.46 ? 276 ILE A CG1 1 ATOM 1944 C CG2 . ILE A 1 244 ? 15.471 -17.650 7.157 1.00 30.34 ? 276 ILE A CG2 1 ATOM 1945 C CD1 . ILE A 1 244 ? 16.011 -15.418 5.010 1.00 30.95 ? 276 ILE A CD1 1 ATOM 1946 N N . ASP A 1 245 ? 15.622 -20.652 5.297 1.00 35.50 ? 277 ASP A N 1 ATOM 1947 C CA . ASP A 1 245 ? 15.971 -21.980 5.783 1.00 38.00 ? 277 ASP A CA 1 ATOM 1948 C C . ASP A 1 245 ? 17.223 -22.461 5.131 1.00 36.28 ? 277 ASP A C 1 ATOM 1949 O O . ASP A 1 245 ? 18.156 -22.877 5.812 1.00 37.14 ? 277 ASP A O 1 ATOM 1950 C CB . ASP A 1 245 ? 14.866 -22.973 5.527 1.00 42.88 ? 277 ASP A CB 1 ATOM 1951 C CG . ASP A 1 245 ? 13.846 -22.969 6.627 1.00 51.31 ? 277 ASP A CG 1 ATOM 1952 O OD1 . ASP A 1 245 ? 13.118 -21.952 6.767 1.00 61.69 ? 277 ASP A OD1 1 ATOM 1953 O OD2 . ASP A 1 245 ? 13.791 -23.975 7.371 1.00 56.37 -1 277 ASP A OD2 1 ATOM 1954 N N . ILE A 1 246 ? 17.261 -22.372 3.810 1.00 33.17 ? 278 ILE A N 1 ATOM 1955 C CA . ILE A 1 246 ? 18.453 -22.765 3.090 1.00 31.91 ? 278 ILE A CA 1 ATOM 1956 C C . ILE A 1 246 ? 19.683 -22.025 3.630 1.00 31.49 ? 278 ILE A C 1 ATOM 1957 O O . ILE A 1 246 ? 20.722 -22.640 3.827 1.00 30.80 ? 278 ILE A O 1 ATOM 1958 C CB . ILE A 1 246 ? 18.320 -22.564 1.555 1.00 30.82 ? 278 ILE A CB 1 ATOM 1959 C CG1 . ILE A 1 246 ? 17.295 -23.539 0.966 1.00 29.39 ? 278 ILE A CG1 1 ATOM 1960 C CG2 . ILE A 1 246 ? 19.668 -22.770 0.857 1.00 30.21 ? 278 ILE A CG2 1 ATOM 1961 C CD1 . ILE A 1 246 ? 16.800 -23.156 -0.414 1.00 28.55 ? 278 ILE A CD1 1 ATOM 1962 N N . PHE A 1 247 ? 19.569 -20.720 3.860 1.00 32.50 ? 279 PHE A N 1 ATOM 1963 C CA . PHE A 1 247 ? 20.732 -19.930 4.282 1.00 33.14 ? 279 PHE A CA 1 ATOM 1964 C C . PHE A 1 247 ? 21.091 -20.274 5.707 1.00 32.23 ? 279 PHE A C 1 ATOM 1965 O O . PHE A 1 247 ? 22.270 -20.325 6.064 1.00 29.20 ? 279 PHE A O 1 ATOM 1966 C CB . PHE A 1 247 ? 20.475 -18.415 4.174 1.00 35.08 ? 279 PHE A CB 1 ATOM 1967 C CG . PHE A 1 247 ? 20.343 -17.886 2.748 1.00 36.11 ? 279 PHE A CG 1 ATOM 1968 C CD1 . PHE A 1 247 ? 21.046 -18.452 1.679 1.00 36.74 ? 279 PHE A CD1 1 ATOM 1969 C CD2 . PHE A 1 247 ? 19.537 -16.783 2.490 1.00 36.46 ? 279 PHE A CD2 1 ATOM 1970 C CE1 . PHE A 1 247 ? 20.928 -17.943 0.390 1.00 36.88 ? 279 PHE A CE1 1 ATOM 1971 C CE2 . PHE A 1 247 ? 19.412 -16.275 1.208 1.00 37.35 ? 279 PHE A CE2 1 ATOM 1972 C CZ . PHE A 1 247 ? 20.111 -16.853 0.157 1.00 37.89 ? 279 PHE A CZ 1 ATOM 1973 N N . GLN A 1 248 ? 20.065 -20.502 6.521 1.00 33.56 ? 280 GLN A N 1 ATOM 1974 C CA . GLN A 1 248 ? 20.270 -21.006 7.863 1.00 35.19 ? 280 GLN A CA 1 ATOM 1975 C C . GLN A 1 248 ? 21.125 -22.266 7.806 1.00 37.41 ? 280 GLN A C 1 ATOM 1976 O O . GLN A 1 248 ? 22.225 -22.283 8.365 1.00 39.61 ? 280 GLN A O 1 ATOM 1977 C CB . GLN A 1 248 ? 18.940 -21.296 8.553 1.00 36.00 ? 280 GLN A CB 1 ATOM 1978 C CG . GLN A 1 248 ? 18.470 -20.167 9.452 1.00 37.60 ? 280 GLN A CG 1 ATOM 1979 C CD . GLN A 1 248 ? 16.970 -20.182 9.749 1.00 40.24 ? 280 GLN A CD 1 ATOM 1980 O OE1 . GLN A 1 248 ? 16.189 -20.944 9.170 1.00 41.08 ? 280 GLN A OE1 1 ATOM 1981 N NE2 . GLN A 1 248 ? 16.559 -19.308 10.653 1.00 42.91 ? 280 GLN A NE2 1 ATOM 1982 N N . LYS A 1 249 ? 20.638 -23.292 7.100 1.00 37.05 ? 281 LYS A N 1 ATOM 1983 C CA . LYS A 1 249 ? 21.320 -24.594 7.027 1.00 37.25 ? 281 LYS A CA 1 ATOM 1984 C C . LYS A 1 249 ? 22.810 -24.488 6.648 1.00 37.15 ? 281 LYS A C 1 ATOM 1985 O O . LYS A 1 249 ? 23.661 -25.080 7.298 1.00 37.08 ? 281 LYS A O 1 ATOM 1986 C CB . LYS A 1 249 ? 20.573 -25.563 6.084 1.00 39.91 ? 281 LYS A CB 1 ATOM 1987 C CG . LYS A 1 249 ? 19.100 -25.848 6.492 1.00 43.87 ? 281 LYS A CG 1 ATOM 1988 C CD . LYS A 1 249 ? 18.525 -27.240 6.122 1.00 44.26 ? 281 LYS A CD 1 ATOM 1989 C CE . LYS A 1 249 ? 18.522 -27.576 4.616 1.00 46.16 ? 281 LYS A CE 1 ATOM 1990 N NZ . LYS A 1 249 ? 17.402 -27.010 3.790 1.00 45.04 1 281 LYS A NZ 1 ATOM 1991 N N . TYR A 1 250 ? 23.131 -23.689 5.638 1.00 38.67 ? 282 TYR A N 1 ATOM 1992 C CA . TYR A 1 250 ? 24.497 -23.588 5.129 1.00 37.97 ? 282 TYR A CA 1 ATOM 1993 C C . TYR A 1 250 ? 25.227 -22.290 5.488 1.00 36.76 ? 282 TYR A C 1 ATOM 1994 O O . TYR A 1 250 ? 26.097 -21.855 4.733 1.00 37.19 ? 282 TYR A O 1 ATOM 1995 C CB . TYR A 1 250 ? 24.451 -23.711 3.612 1.00 39.39 ? 282 TYR A CB 1 ATOM 1996 C CG . TYR A 1 250 ? 23.983 -25.059 3.109 1.00 42.63 ? 282 TYR A CG 1 ATOM 1997 C CD1 . TYR A 1 250 ? 24.917 -26.041 2.731 1.00 43.17 ? 282 TYR A CD1 1 ATOM 1998 C CD2 . TYR A 1 250 ? 22.613 -25.358 2.982 1.00 43.57 ? 282 TYR A CD2 1 ATOM 1999 C CE1 . TYR A 1 250 ? 24.509 -27.275 2.261 1.00 42.67 ? 282 TYR A CE1 1 ATOM 2000 C CE2 . TYR A 1 250 ? 22.194 -26.601 2.509 1.00 44.48 ? 282 TYR A CE2 1 ATOM 2001 C CZ . TYR A 1 250 ? 23.153 -27.552 2.152 1.00 44.20 ? 282 TYR A CZ 1 ATOM 2002 O OH . TYR A 1 250 ? 22.779 -28.779 1.674 1.00 43.41 ? 282 TYR A OH 1 ATOM 2003 N N . SER A 1 251 ? 24.904 -21.678 6.623 1.00 35.06 ? 283 SER A N 1 ATOM 2004 C CA . SER A 1 251 ? 25.470 -20.362 6.962 1.00 35.29 ? 283 SER A CA 1 ATOM 2005 C C . SER A 1 251 ? 26.969 -20.393 7.222 1.00 35.11 ? 283 SER A C 1 ATOM 2006 O O . SER A 1 251 ? 27.679 -19.397 7.056 1.00 32.66 ? 283 SER A O 1 ATOM 2007 C CB . SER A 1 251 ? 24.778 -19.770 8.184 1.00 36.90 ? 283 SER A CB 1 ATOM 2008 O OG . SER A 1 251 ? 25.112 -20.481 9.362 1.00 39.78 ? 283 SER A OG 1 ATOM 2009 N N . ASP A 1 252 ? 27.434 -21.547 7.666 1.00 37.40 ? 284 ASP A N 1 ATOM 2010 C CA . ASP A 1 252 ? 28.861 -21.808 7.842 1.00 38.34 ? 284 ASP A CA 1 ATOM 2011 C C . ASP A 1 252 ? 29.624 -21.569 6.536 1.00 31.80 ? 284 ASP A C 1 ATOM 2012 O O . ASP A 1 252 ? 30.747 -21.109 6.573 1.00 29.80 ? 284 ASP A O 1 ATOM 2013 C CB . ASP A 1 252 ? 29.051 -23.236 8.359 1.00 43.89 ? 284 ASP A CB 1 ATOM 2014 C CG . ASP A 1 252 ? 27.936 -24.182 7.861 1.00 51.76 ? 284 ASP A CG 1 ATOM 2015 O OD1 . ASP A 1 252 ? 26.774 -24.058 8.333 1.00 51.67 ? 284 ASP A OD1 1 ATOM 2016 O OD2 . ASP A 1 252 ? 28.207 -25.017 6.964 1.00 58.96 -1 284 ASP A OD2 1 ATOM 2017 N N . VAL A 1 253 ? 28.997 -21.833 5.389 1.00 28.95 ? 285 VAL A N 1 ATOM 2018 C CA . VAL A 1 253 ? 29.658 -21.643 4.069 1.00 27.83 ? 285 VAL A CA 1 ATOM 2019 C C . VAL A 1 253 ? 29.587 -20.227 3.504 1.00 25.46 ? 285 VAL A C 1 ATOM 2020 O O . VAL A 1 253 ? 30.516 -19.776 2.836 1.00 24.29 ? 285 VAL A O 1 ATOM 2021 C CB . VAL A 1 253 ? 29.060 -22.524 2.947 1.00 27.98 ? 285 VAL A CB 1 ATOM 2022 C CG1 . VAL A 1 253 ? 30.095 -22.710 1.847 1.00 27.55 ? 285 VAL A CG1 1 ATOM 2023 C CG2 . VAL A 1 253 ? 28.607 -23.876 3.473 1.00 29.13 ? 285 VAL A CG2 1 ATOM 2024 N N . ILE A 1 254 ? 28.465 -19.560 3.745 1.00 23.32 ? 286 ILE A N 1 ATOM 2025 C CA . ILE A 1 254 ? 28.204 -18.271 3.174 1.00 22.69 ? 286 ILE A CA 1 ATOM 2026 C C . ILE A 1 254 ? 28.916 -17.236 4.005 1.00 23.37 ? 286 ILE A C 1 ATOM 2027 O O . ILE A 1 254 ? 28.653 -17.090 5.191 1.00 25.30 ? 286 ILE A O 1 ATOM 2028 C CB . ILE A 1 254 ? 26.718 -17.943 3.217 1.00 22.87 ? 286 ILE A CB 1 ATOM 2029 C CG1 . ILE A 1 254 ? 25.913 -19.078 2.576 1.00 23.09 ? 286 ILE A CG1 1 ATOM 2030 C CG2 . ILE A 1 254 ? 26.466 -16.590 2.553 1.00 22.58 ? 286 ILE A CG2 1 ATOM 2031 C CD1 . ILE A 1 254 ? 24.419 -18.957 2.782 1.00 23.29 ? 286 ILE A CD1 1 ATOM 2032 N N . ALA A 1 255 ? 29.816 -16.505 3.377 1.00 23.63 ? 287 ALA A N 1 ATOM 2033 C CA . ALA A 1 255 ? 30.660 -15.557 4.078 1.00 23.16 ? 287 ALA A CA 1 ATOM 2034 C C . ALA A 1 255 ? 30.168 -14.148 3.875 1.00 22.54 ? 287 ALA A C 1 ATOM 2035 O O . ALA A 1 255 ? 30.811 -13.199 4.317 1.00 22.75 ? 287 ALA A O 1 ATOM 2036 C CB . ALA A 1 255 ? 32.097 -15.691 3.588 1.00 23.64 ? 287 ALA A CB 1 ATOM 2037 N N . GLY A 1 256 ? 29.034 -14.014 3.196 1.00 23.11 ? 288 GLY A N 1 ATOM 2038 C CA . GLY A 1 256 ? 28.405 -12.706 2.968 1.00 23.49 ? 288 GLY A CA 1 ATOM 2039 C C . GLY A 1 256 ? 27.351 -12.733 1.868 1.00 22.20 ? 288 GLY A C 1 ATOM 2040 O O . GLY A 1 256 ? 27.438 -13.537 0.940 1.00 22.29 ? 288 GLY A O 1 ATOM 2041 N N . GLN A 1 257 ? 26.353 -11.861 1.986 1.00 20.32 ? 289 GLN A N 1 ATOM 2042 C CA . GLN A 1 257 ? 25.308 -11.750 0.993 1.00 18.91 ? 289 GLN A CA 1 ATOM 2043 C C . GLN A 1 257 ? 25.123 -10.312 0.603 1.00 19.32 ? 289 GLN A C 1 ATOM 2044 O O . GLN A 1 257 ? 25.403 -9.397 1.379 1.00 18.75 ? 289 GLN A O 1 ATOM 2045 C CB . GLN A 1 257 ? 24.008 -12.281 1.512 1.00 17.77 ? 289 GLN A CB 1 ATOM 2046 C CG . GLN A 1 257 ? 24.109 -13.688 2.006 1.00 17.43 ? 289 GLN A CG 1 ATOM 2047 C CD . GLN A 1 257 ? 22.785 -14.170 2.536 1.00 17.58 ? 289 GLN A CD 1 ATOM 2048 O OE1 . GLN A 1 257 ? 21.772 -14.078 1.857 1.00 17.81 ? 289 GLN A OE1 1 ATOM 2049 N NE2 . GLN A 1 257 ? 22.780 -14.674 3.758 1.00 17.62 ? 289 GLN A NE2 1 ATOM 2050 N N . PHE A 1 258 ? 24.631 -10.139 -0.620 1.00 19.72 ? 290 PHE A N 1 ATOM 2051 C CA . PHE A 1 258 ? 24.659 -8.855 -1.306 1.00 19.92 ? 290 PHE A CA 1 ATOM 2052 C C . PHE A 1 258 ? 23.447 -8.714 -2.223 1.00 19.13 ? 290 PHE A C 1 ATOM 2053 O O . PHE A 1 258 ? 23.174 -9.575 -3.058 1.00 19.91 ? 290 PHE A O 1 ATOM 2054 C CB . PHE A 1 258 ? 25.974 -8.721 -2.096 1.00 20.01 ? 290 PHE A CB 1 ATOM 2055 C CG . PHE A 1 258 ? 27.187 -9.027 -1.274 1.00 20.37 ? 290 PHE A CG 1 ATOM 2056 C CD1 . PHE A 1 258 ? 27.832 -8.024 -0.571 1.00 21.14 ? 290 PHE A CD1 1 ATOM 2057 C CD2 . PHE A 1 258 ? 27.650 -10.326 -1.156 1.00 20.26 ? 290 PHE A CD2 1 ATOM 2058 C CE1 . PHE A 1 258 ? 28.947 -8.309 0.206 1.00 21.66 ? 290 PHE A CE1 1 ATOM 2059 C CE2 . PHE A 1 258 ? 28.743 -10.618 -0.377 1.00 20.64 ? 290 PHE A CE2 1 ATOM 2060 C CZ . PHE A 1 258 ? 29.397 -9.613 0.305 1.00 21.13 ? 290 PHE A CZ 1 ATOM 2061 N N . TYR A 1 259 ? 22.726 -7.619 -2.070 1.00 17.67 ? 291 TYR A N 1 ATOM 2062 C CA . TYR A 1 259 ? 21.535 -7.415 -2.834 1.00 16.80 ? 291 TYR A CA 1 ATOM 2063 C C . TYR A 1 259 ? 21.402 -5.965 -3.232 1.00 16.64 ? 291 TYR A C 1 ATOM 2064 O O . TYR A 1 259 ? 22.196 -5.113 -2.815 1.00 16.96 ? 291 TYR A O 1 ATOM 2065 C CB . TYR A 1 259 ? 20.351 -7.771 -1.975 1.00 17.02 ? 291 TYR A CB 1 ATOM 2066 C CG . TYR A 1 259 ? 20.358 -9.154 -1.411 1.00 16.73 ? 291 TYR A CG 1 ATOM 2067 C CD1 . TYR A 1 259 ? 19.910 -10.206 -2.157 1.00 16.86 ? 291 TYR A CD1 1 ATOM 2068 C CD2 . TYR A 1 259 ? 20.775 -9.399 -0.123 1.00 16.75 ? 291 TYR A CD2 1 ATOM 2069 C CE1 . TYR A 1 259 ? 19.879 -11.487 -1.648 1.00 17.11 ? 291 TYR A CE1 1 ATOM 2070 C CE2 . TYR A 1 259 ? 20.744 -10.677 0.405 1.00 17.09 ? 291 TYR A CE2 1 ATOM 2071 C CZ . TYR A 1 259 ? 20.296 -11.726 -0.373 1.00 17.26 ? 291 TYR A CZ 1 ATOM 2072 O OH . TYR A 1 259 ? 20.263 -13.025 0.089 1.00 17.12 ? 291 TYR A OH 1 ATOM 2073 N N . GLY A 1 260 ? 20.375 -5.691 -4.038 1.00 16.15 ? 292 GLY A N 1 ATOM 2074 C CA . GLY A 1 260 ? 20.011 -4.331 -4.437 1.00 15.31 ? 292 GLY A CA 1 ATOM 2075 C C . GLY A 1 260 ? 18.517 -4.182 -4.333 1.00 14.81 ? 292 GLY A C 1 ATOM 2076 O O . GLY A 1 260 ? 17.932 -4.467 -3.301 1.00 13.99 ? 292 GLY A O 1 ATOM 2077 N N . HIS A 1 261 ? 17.910 -3.736 -5.421 1.00 15.09 ? 293 HIS A N 1 ATOM 2078 C CA . HIS A 1 261 ? 16.462 -3.705 -5.606 1.00 14.85 ? 293 HIS A CA 1 ATOM 2079 C C . HIS A 1 261 ? 15.809 -2.601 -4.797 1.00 14.38 ? 293 HIS A C 1 ATOM 2080 O O . HIS A 1 261 ? 15.145 -1.797 -5.374 1.00 14.94 ? 293 HIS A O 1 ATOM 2081 C CB . HIS A 1 261 ? 15.819 -5.067 -5.346 1.00 15.13 ? 293 HIS A CB 1 ATOM 2082 C CG . HIS A 1 261 ? 14.332 -5.055 -5.463 1.00 16.07 ? 293 HIS A CG 1 ATOM 2083 N ND1 . HIS A 1 261 ? 13.673 -4.729 -6.629 1.00 16.56 ? 293 HIS A ND1 1 ATOM 2084 C CD2 . HIS A 1 261 ? 13.366 -5.343 -4.557 1.00 16.77 ? 293 HIS A CD2 1 ATOM 2085 C CE1 . HIS A 1 261 ? 12.367 -4.797 -6.434 1.00 16.84 ? 293 HIS A CE1 1 ATOM 2086 N NE2 . HIS A 1 261 ? 12.152 -5.168 -5.183 1.00 17.10 ? 293 HIS A NE2 1 ATOM 2087 N N . THR A 1 262 ? 16.037 -2.506 -3.492 1.00 13.88 ? 294 THR A N 1 ATOM 2088 C CA . THR A 1 262 ? 15.406 -1.438 -2.677 1.00 13.28 ? 294 THR A CA 1 ATOM 2089 C C . THR A 1 262 ? 15.906 -0.030 -2.934 1.00 12.93 ? 294 THR A C 1 ATOM 2090 O O . THR A 1 262 ? 15.272 0.920 -2.496 1.00 12.52 ? 294 THR A O 1 ATOM 2091 C CB . THR A 1 262 ? 15.638 -1.636 -1.171 1.00 13.36 ? 294 THR A CB 1 ATOM 2092 O OG1 . THR A 1 262 ? 17.010 -1.329 -0.850 1.00 13.43 ? 294 THR A OG1 1 ATOM 2093 C CG2 . THR A 1 262 ? 15.258 -3.063 -0.734 1.00 13.38 ? 294 THR A CG2 1 ATOM 2094 N N . HIS A 1 263 ? 17.063 0.099 -3.581 1.00 13.08 ? 295 HIS A N 1 ATOM 2095 C CA . HIS A 1 263 ? 17.704 1.397 -3.808 1.00 13.21 ? 295 HIS A CA 1 ATOM 2096 C C . HIS A 1 263 ? 18.148 2.083 -2.494 1.00 13.05 ? 295 HIS A C 1 ATOM 2097 O O . HIS A 1 263 ? 18.390 3.294 -2.444 1.00 12.77 ? 295 HIS A O 1 ATOM 2098 C CB . HIS A 1 263 ? 16.757 2.335 -4.562 1.00 13.62 ? 295 HIS A CB 1 ATOM 2099 C CG . HIS A 1 263 ? 16.531 1.966 -5.988 1.00 13.67 ? 295 HIS A CG 1 ATOM 2100 N ND1 . HIS A 1 263 ? 16.196 2.907 -6.945 1.00 14.03 ? 295 HIS A ND1 1 ATOM 2101 C CD2 . HIS A 1 263 ? 16.606 0.777 -6.628 1.00 13.44 ? 295 HIS A CD2 1 ATOM 2102 C CE1 . HIS A 1 263 ? 16.059 2.299 -8.113 1.00 13.93 ? 295 HIS A CE1 1 ATOM 2103 N NE2 . HIS A 1 263 ? 16.311 1.011 -7.949 1.00 13.49 ? 295 HIS A NE2 1 ATOM 2104 N N . ARG A 1 264 ? 18.276 1.318 -1.426 1.00 12.89 ? 296 ARG A N 1 ATOM 2105 C CA . ARG A 1 264 ? 18.573 1.916 -0.140 1.00 12.77 ? 296 ARG A CA 1 ATOM 2106 C C . ARG A 1 264 ? 19.712 1.181 0.525 1.00 12.78 ? 296 ARG A C 1 ATOM 2107 O O . ARG A 1 264 ? 19.941 -0.001 0.254 1.00 12.93 ? 296 ARG A O 1 ATOM 2108 C CB . ARG A 1 264 ? 17.335 1.848 0.750 1.00 12.66 ? 296 ARG A CB 1 ATOM 2109 C CG . ARG A 1 264 ? 16.099 2.499 0.154 1.00 12.40 ? 296 ARG A CG 1 ATOM 2110 C CD . ARG A 1 264 ? 16.061 3.966 0.465 1.00 12.58 ? 296 ARG A CD 1 ATOM 2111 N NE . ARG A 1 264 ? 15.048 4.642 -0.337 1.00 12.95 ? 296 ARG A NE 1 ATOM 2112 C CZ . ARG A 1 264 ? 15.237 5.089 -1.578 1.00 13.21 ? 296 ARG A CZ 1 ATOM 2113 N NH1 . ARG A 1 264 ? 16.396 4.937 -2.188 1.00 13.53 1 296 ARG A NH1 1 ATOM 2114 N NH2 . ARG A 1 264 ? 14.258 5.693 -2.226 1.00 13.65 ? 296 ARG A NH2 1 ATOM 2115 N N . ASP A 1 265 ? 20.414 1.881 1.404 1.00 12.83 ? 297 ASP A N 1 ATOM 2116 C CA . ASP A 1 265 ? 21.516 1.286 2.155 1.00 12.95 ? 297 ASP A CA 1 ATOM 2117 C C . ASP A 1 265 ? 20.987 0.567 3.394 1.00 12.98 ? 297 ASP A C 1 ATOM 2118 O O . ASP A 1 265 ? 20.552 1.216 4.342 1.00 12.87 ? 297 ASP A O 1 ATOM 2119 C CB . ASP A 1 265 ? 22.488 2.379 2.585 1.00 12.77 ? 297 ASP A CB 1 ATOM 2120 C CG . ASP A 1 265 ? 23.742 1.821 3.172 1.00 12.75 ? 297 ASP A CG 1 ATOM 2121 O OD1 . ASP A 1 265 ? 23.672 0.732 3.804 1.00 13.04 ? 297 ASP A OD1 1 ATOM 2122 O OD2 . ASP A 1 265 ? 24.801 2.454 2.983 1.00 12.51 -1 297 ASP A OD2 1 ATOM 2123 N N . SER A 1 266 ? 21.033 -0.754 3.397 1.00 12.97 ? 298 SER A N 1 ATOM 2124 C CA . SER A 1 266 ? 20.474 -1.508 4.508 1.00 13.84 ? 298 SER A CA 1 ATOM 2125 C C . SER A 1 266 ? 21.376 -2.646 4.960 1.00 14.66 ? 298 SER A C 1 ATOM 2126 O O . SER A 1 266 ? 22.088 -3.224 4.140 1.00 15.80 ? 298 SER A O 1 ATOM 2127 C CB . SER A 1 266 ? 19.105 -2.069 4.126 1.00 13.90 ? 298 SER A CB 1 ATOM 2128 O OG . SER A 1 266 ? 18.058 -1.204 4.534 1.00 14.54 ? 298 SER A OG 1 ATOM 2129 N N . ILE A 1 267 ? 21.380 -2.963 6.256 1.00 15.10 ? 299 ILE A N 1 ATOM 2130 C CA . ILE A 1 267 ? 21.965 -4.236 6.676 1.00 16.00 ? 299 ILE A CA 1 ATOM 2131 C C . ILE A 1 267 ? 20.887 -5.173 7.199 1.00 16.18 ? 299 ILE A C 1 ATOM 2132 O O . ILE A 1 267 ? 19.786 -4.770 7.568 1.00 16.24 ? 299 ILE A O 1 ATOM 2133 C CB . ILE A 1 267 ? 23.068 -4.125 7.748 1.00 16.73 ? 299 ILE A CB 1 ATOM 2134 C CG1 . ILE A 1 267 ? 22.491 -3.599 9.039 1.00 18.05 ? 299 ILE A CG1 1 ATOM 2135 C CG2 . ILE A 1 267 ? 24.212 -3.218 7.328 1.00 16.69 ? 299 ILE A CG2 1 ATOM 2136 C CD1 . ILE A 1 267 ? 23.476 -3.685 10.183 1.00 19.09 ? 299 ILE A CD1 1 ATOM 2137 N N . MET A 1 268 ? 21.221 -6.444 7.212 1.00 16.73 ? 300 MET A N 1 ATOM 2138 C CA . MET A 1 268 ? 20.367 -7.452 7.818 1.00 17.28 ? 300 MET A CA 1 ATOM 2139 C C . MET A 1 268 ? 21.255 -8.516 8.412 1.00 16.81 ? 300 MET A C 1 ATOM 2140 O O . MET A 1 268 ? 22.406 -8.683 7.984 1.00 16.71 ? 300 MET A O 1 ATOM 2141 C CB . MET A 1 268 ? 19.428 -8.087 6.796 1.00 17.49 ? 300 MET A CB 1 ATOM 2142 C CG . MET A 1 268 ? 18.120 -7.355 6.634 1.00 17.52 ? 300 MET A CG 1 ATOM 2143 S SD . MET A 1 268 ? 17.156 -8.175 5.356 1.00 18.30 ? 300 MET A SD 1 ATOM 2144 C CE . MET A 1 268 ? 18.023 -7.747 3.852 1.00 18.45 ? 300 MET A CE 1 ATOM 2145 N N . VAL A 1 269 ? 20.704 -9.224 9.391 1.00 16.20 ? 301 VAL A N 1 ATOM 2146 C CA . VAL A 1 269 ? 21.445 -10.216 10.115 1.00 16.25 ? 301 VAL A CA 1 ATOM 2147 C C . VAL A 1 269 ? 20.589 -11.432 10.231 1.00 17.00 ? 301 VAL A C 1 ATOM 2148 O O . VAL A 1 269 ? 19.541 -11.409 10.866 1.00 17.21 ? 301 VAL A O 1 ATOM 2149 C CB . VAL A 1 269 ? 21.814 -9.733 11.512 1.00 16.14 ? 301 VAL A CB 1 ATOM 2150 C CG1 . VAL A 1 269 ? 22.685 -10.776 12.187 1.00 16.13 ? 301 VAL A CG1 1 ATOM 2151 C CG2 . VAL A 1 269 ? 22.555 -8.405 11.420 1.00 16.34 ? 301 VAL A CG2 1 ATOM 2152 N N . LEU A 1 270 ? 21.036 -12.497 9.597 1.00 18.22 ? 302 LEU A N 1 ATOM 2153 C CA . LEU A 1 270 ? 20.317 -13.751 9.633 1.00 19.27 ? 302 LEU A CA 1 ATOM 2154 C C . LEU A 1 270 ? 20.653 -14.400 10.955 1.00 20.44 ? 302 LEU A C 1 ATOM 2155 O O . LEU A 1 270 ? 21.821 -14.399 11.357 1.00 20.61 ? 302 LEU A O 1 ATOM 2156 C CB . LEU A 1 270 ? 20.782 -14.621 8.474 1.00 19.11 ? 302 LEU A CB 1 ATOM 2157 C CG . LEU A 1 270 ? 20.221 -16.032 8.416 1.00 19.58 ? 302 LEU A CG 1 ATOM 2158 C CD1 . LEU A 1 270 ? 18.701 -16.008 8.441 1.00 19.35 ? 302 LEU A CD1 1 ATOM 2159 C CD2 . LEU A 1 270 ? 20.752 -16.741 7.163 1.00 20.01 ? 302 LEU A CD2 1 ATOM 2160 N N . SER A 1 271 ? 19.654 -14.911 11.658 1.00 22.39 ? 303 SER A N 1 ATOM 2161 C CA . SER A 1 271 ? 19.936 -15.693 12.870 1.00 25.29 ? 303 SER A CA 1 ATOM 2162 C C . SER A 1 271 ? 19.627 -17.173 12.658 1.00 28.26 ? 303 SER A C 1 ATOM 2163 O O . SER A 1 271 ? 18.896 -17.538 11.751 1.00 28.79 ? 303 SER A O 1 ATOM 2164 C CB . SER A 1 271 ? 19.177 -15.138 14.075 1.00 25.08 ? 303 SER A CB 1 ATOM 2165 O OG . SER A 1 271 ? 19.582 -13.803 14.347 1.00 24.96 ? 303 SER A OG 1 ATOM 2166 N N . ASP A 1 272 ? 20.211 -18.040 13.469 1.00 32.94 ? 304 ASP A N 1 ATOM 2167 C CA . ASP A 1 272 ? 19.918 -19.463 13.332 1.00 36.37 ? 304 ASP A CA 1 ATOM 2168 C C . ASP A 1 272 ? 18.541 -19.712 13.960 1.00 38.67 ? 304 ASP A C 1 ATOM 2169 O O . ASP A 1 272 ? 17.968 -18.827 14.601 1.00 36.98 ? 304 ASP A O 1 ATOM 2170 C CB . ASP A 1 272 ? 21.058 -20.363 13.897 1.00 37.64 ? 304 ASP A CB 1 ATOM 2171 C CG . ASP A 1 272 ? 21.206 -20.294 15.431 1.00 38.78 ? 304 ASP A CG 1 ATOM 2172 O OD1 . ASP A 1 272 ? 20.495 -19.499 16.083 1.00 40.26 ? 304 ASP A OD1 1 ATOM 2173 O OD2 . ASP A 1 272 ? 22.042 -21.048 15.992 1.00 39.54 -1 304 ASP A OD2 1 ATOM 2174 N N . LYS A 1 273 ? 18.000 -20.900 13.748 1.00 43.06 ? 305 LYS A N 1 ATOM 2175 C CA . LYS A 1 273 ? 16.701 -21.252 14.296 1.00 47.61 ? 305 LYS A CA 1 ATOM 2176 C C . LYS A 1 273 ? 16.671 -21.038 15.801 1.00 46.72 ? 305 LYS A C 1 ATOM 2177 O O . LYS A 1 273 ? 15.632 -20.744 16.366 1.00 47.12 ? 305 LYS A O 1 ATOM 2178 C CB . LYS A 1 273 ? 16.384 -22.709 13.962 1.00 54.73 ? 305 LYS A CB 1 ATOM 2179 C CG . LYS A 1 273 ? 15.985 -22.946 12.506 1.00 60.56 ? 305 LYS A CG 1 ATOM 2180 C CD . LYS A 1 273 ? 14.463 -22.903 12.355 1.00 67.55 ? 305 LYS A CD 1 ATOM 2181 C CE . LYS A 1 273 ? 13.998 -22.722 10.913 1.00 72.71 ? 305 LYS A CE 1 ATOM 2182 N NZ . LYS A 1 273 ? 14.554 -23.765 10.006 1.00 73.92 1 305 LYS A NZ 1 ATOM 2183 N N . LYS A 1 274 ? 17.825 -21.185 16.438 1.00 48.31 ? 306 LYS A N 1 ATOM 2184 C CA . LYS A 1 274 ? 17.973 -20.969 17.880 1.00 51.20 ? 306 LYS A CA 1 ATOM 2185 C C . LYS A 1 274 ? 17.861 -19.491 18.304 1.00 45.68 ? 306 LYS A C 1 ATOM 2186 O O . LYS A 1 274 ? 17.539 -19.209 19.447 1.00 44.88 ? 306 LYS A O 1 ATOM 2187 C CB . LYS A 1 274 ? 19.329 -21.544 18.357 1.00 57.72 ? 306 LYS A CB 1 ATOM 2188 C CG . LYS A 1 274 ? 19.337 -22.166 19.758 1.00 62.10 ? 306 LYS A CG 1 ATOM 2189 C CD . LYS A 1 274 ? 19.250 -23.697 19.737 1.00 65.70 ? 306 LYS A CD 1 ATOM 2190 C CE . LYS A 1 274 ? 17.819 -24.220 19.658 1.00 67.49 ? 306 LYS A CE 1 ATOM 2191 N NZ . LYS A 1 274 ? 17.084 -23.999 20.938 1.00 70.60 1 306 LYS A NZ 1 ATOM 2192 N N . GLY A 1 275 ? 18.144 -18.563 17.395 1.00 41.74 ? 307 GLY A N 1 ATOM 2193 C CA . GLY A 1 275 ? 18.089 -17.125 17.688 1.00 39.43 ? 307 GLY A CA 1 ATOM 2194 C C . GLY A 1 275 ? 19.445 -16.439 17.797 1.00 38.11 ? 307 GLY A C 1 ATOM 2195 O O . GLY A 1 275 ? 19.535 -15.341 18.328 1.00 38.74 ? 307 GLY A O 1 ATOM 2196 N N . SER A 1 276 ? 20.491 -17.069 17.263 1.00 36.31 ? 308 SER A N 1 ATOM 2197 C CA . SER A 1 276 ? 21.877 -16.583 17.358 1.00 33.35 ? 308 SER A CA 1 ATOM 2198 C C . SER A 1 276 ? 22.357 -16.080 15.989 1.00 29.93 ? 308 SER A C 1 ATOM 2199 O O . SER A 1 276 ? 22.255 -16.813 15.015 1.00 29.77 ? 308 SER A O 1 ATOM 2200 C CB . SER A 1 276 ? 22.767 -17.746 17.791 1.00 33.90 ? 308 SER A CB 1 ATOM 2201 O OG . SER A 1 276 ? 23.568 -17.391 18.887 1.00 36.94 ? 308 SER A OG 1 ATOM 2202 N N . PRO A 1 277 ? 22.887 -14.846 15.899 1.00 26.14 ? 309 PRO A N 1 ATOM 2203 C CA . PRO A 1 277 ? 23.268 -14.309 14.593 1.00 24.55 ? 309 PRO A CA 1 ATOM 2204 C C . PRO A 1 277 ? 24.282 -15.177 13.892 1.00 23.38 ? 309 PRO A C 1 ATOM 2205 O O . PRO A 1 277 ? 25.197 -15.652 14.533 1.00 23.29 ? 309 PRO A O 1 ATOM 2206 C CB . PRO A 1 277 ? 23.906 -12.966 14.932 1.00 24.86 ? 309 PRO A CB 1 ATOM 2207 C CG . PRO A 1 277 ? 24.319 -13.070 16.350 1.00 25.52 ? 309 PRO A CG 1 ATOM 2208 C CD . PRO A 1 277 ? 23.266 -13.933 16.982 1.00 26.03 ? 309 PRO A CD 1 ATOM 2209 N N . VAL A 1 278 ? 24.111 -15.388 12.592 1.00 23.08 ? 310 VAL A N 1 ATOM 2210 C CA . VAL A 1 278 ? 24.977 -16.312 11.840 1.00 22.63 ? 310 VAL A CA 1 ATOM 2211 C C . VAL A 1 278 ? 25.305 -15.901 10.420 1.00 20.99 ? 310 VAL A C 1 ATOM 2212 O O . VAL A 1 278 ? 26.081 -16.564 9.789 1.00 21.10 ? 310 VAL A O 1 ATOM 2213 C CB . VAL A 1 278 ? 24.376 -17.753 11.746 1.00 23.92 ? 310 VAL A CB 1 ATOM 2214 C CG1 . VAL A 1 278 ? 24.255 -18.396 13.122 1.00 23.92 ? 310 VAL A CG1 1 ATOM 2215 C CG2 . VAL A 1 278 ? 23.019 -17.770 11.031 1.00 24.25 ? 310 VAL A CG2 1 ATOM 2216 N N . ASN A 1 279 ? 24.712 -14.855 9.877 1.00 20.14 ? 311 ASN A N 1 ATOM 2217 C CA . ASN A 1 279 ? 25.101 -14.442 8.524 1.00 19.81 ? 311 ASN A CA 1 ATOM 2218 C C . ASN A 1 279 ? 24.775 -12.976 8.371 1.00 18.39 ? 311 ASN A C 1 ATOM 2219 O O . ASN A 1 279 ? 23.728 -12.531 8.848 1.00 18.22 ? 311 ASN A O 1 ATOM 2220 C CB . ASN A 1 279 ? 24.372 -15.281 7.450 1.00 20.58 ? 311 ASN A CB 1 ATOM 2221 C CG . ASN A 1 279 ? 25.263 -15.626 6.258 1.00 20.97 ? 311 ASN A CG 1 ATOM 2222 O OD1 . ASN A 1 279 ? 25.520 -14.799 5.379 1.00 22.67 ? 311 ASN A OD1 1 ATOM 2223 N ND2 . ASN A 1 279 ? 25.734 -16.846 6.230 1.00 20.48 ? 311 ASN A ND2 1 ATOM 2224 N N . SER A 1 280 ? 25.681 -12.232 7.744 1.00 16.80 ? 312 SER A N 1 ATOM 2225 C CA . SER A 1 280 ? 25.472 -10.818 7.497 1.00 15.78 ? 312 SER A CA 1 ATOM 2226 C C . SER A 1 280 ? 25.083 -10.606 6.059 1.00 15.38 ? 312 SER A C 1 ATOM 2227 O O . SER A 1 280 ? 25.689 -11.209 5.147 1.00 15.52 ? 312 SER A O 1 ATOM 2228 C CB . SER A 1 280 ? 26.746 -10.053 7.749 1.00 15.80 ? 312 SER A CB 1 ATOM 2229 O OG . SER A 1 280 ? 27.120 -10.192 9.084 1.00 16.10 ? 312 SER A OG 1 ATOM 2230 N N . LEU A 1 281 ? 24.096 -9.728 5.879 1.00 14.52 ? 313 LEU A N 1 ATOM 2231 C CA . LEU A 1 281 ? 23.532 -9.391 4.588 1.00 14.21 ? 313 LEU A CA 1 ATOM 2232 C C . LEU A 1 281 ? 23.679 -7.898 4.333 1.00 13.79 ? 313 LEU A C 1 ATOM 2233 O O . LEU A 1 281 ? 23.619 -7.090 5.250 1.00 13.83 ? 313 LEU A O 1 ATOM 2234 C CB . LEU A 1 281 ? 22.064 -9.763 4.583 1.00 14.51 ? 313 LEU A CB 1 ATOM 2235 C CG . LEU A 1 281 ? 21.821 -11.276 4.599 1.00 15.12 ? 313 LEU A CG 1 ATOM 2236 C CD1 . LEU A 1 281 ? 22.005 -11.879 5.973 1.00 15.62 ? 313 LEU A CD1 1 ATOM 2237 C CD2 . LEU A 1 281 ? 20.433 -11.648 4.120 1.00 15.45 ? 313 LEU A CD2 1 ATOM 2238 N N . PHE A 1 282 ? 23.875 -7.527 3.080 1.00 13.39 ? 314 PHE A N 1 ATOM 2239 C CA . PHE A 1 282 ? 24.173 -6.138 2.739 1.00 13.16 ? 314 PHE A CA 1 ATOM 2240 C C . PHE A 1 282 ? 23.429 -5.724 1.504 1.00 12.80 ? 314 PHE A C 1 ATOM 2241 O O . PHE A 1 282 ? 23.672 -6.262 0.424 1.00 13.03 ? 314 PHE A O 1 ATOM 2242 C CB . PHE A 1 282 ? 25.657 -5.990 2.497 1.00 13.20 ? 314 PHE A CB 1 ATOM 2243 C CG . PHE A 1 282 ? 26.460 -6.343 3.693 1.00 13.66 ? 314 PHE A CG 1 ATOM 2244 C CD1 . PHE A 1 282 ? 26.847 -5.349 4.594 1.00 13.67 ? 314 PHE A CD1 1 ATOM 2245 C CD2 . PHE A 1 282 ? 26.766 -7.682 3.973 1.00 13.62 ? 314 PHE A CD2 1 ATOM 2246 C CE1 . PHE A 1 282 ? 27.570 -5.674 5.725 1.00 13.70 ? 314 PHE A CE1 1 ATOM 2247 C CE2 . PHE A 1 282 ? 27.482 -8.013 5.102 1.00 13.70 ? 314 PHE A CE2 1 ATOM 2248 C CZ . PHE A 1 282 ? 27.893 -7.005 5.980 1.00 13.88 ? 314 PHE A CZ 1 ATOM 2249 N N . VAL A 1 283 ? 22.510 -4.781 1.676 1.00 12.07 ? 315 VAL A N 1 ATOM 2250 C CA . VAL A 1 283 ? 21.773 -4.229 0.572 1.00 11.63 ? 315 VAL A CA 1 ATOM 2251 C C . VAL A 1 283 ? 22.336 -2.867 0.222 1.00 11.57 ? 315 VAL A C 1 ATOM 2252 O O . VAL A 1 283 ? 22.290 -1.923 1.010 1.00 11.72 ? 315 VAL A O 1 ATOM 2253 C CB . VAL A 1 283 ? 20.294 -4.091 0.892 1.00 11.49 ? 315 VAL A CB 1 ATOM 2254 C CG1 . VAL A 1 283 ? 19.569 -3.499 -0.315 1.00 11.41 ? 315 VAL A CG1 1 ATOM 2255 C CG2 . VAL A 1 283 ? 19.708 -5.442 1.326 1.00 11.33 ? 315 VAL A CG2 1 ATOM 2256 N N . ALA A 1 284 ? 22.838 -2.774 -0.994 1.00 11.46 ? 316 ALA A N 1 ATOM 2257 C CA . ALA A 1 284 ? 23.505 -1.595 -1.470 1.00 11.42 ? 316 ALA A CA 1 ATOM 2258 C C . ALA A 1 284 ? 22.526 -0.681 -2.143 1.00 11.38 ? 316 ALA A C 1 ATOM 2259 O O . ALA A 1 284 ? 21.675 -1.139 -2.896 1.00 11.43 ? 316 ALA A O 1 ATOM 2260 C CB . ALA A 1 284 ? 24.552 -2.014 -2.478 1.00 11.79 ? 316 ALA A CB 1 ATOM 2261 N N . PRO A 1 285 ? 22.668 0.625 -1.936 1.00 11.59 ? 317 PRO A N 1 ATOM 2262 C CA . PRO A 1 285 ? 21.732 1.511 -2.603 1.00 11.94 ? 317 PRO A CA 1 ATOM 2263 C C . PRO A 1 285 ? 22.091 1.691 -4.080 1.00 12.08 ? 317 PRO A C 1 ATOM 2264 O O . PRO A 1 285 ? 23.154 1.276 -4.522 1.00 12.94 ? 317 PRO A O 1 ATOM 2265 C CB . PRO A 1 285 ? 21.888 2.829 -1.829 1.00 11.70 ? 317 PRO A CB 1 ATOM 2266 C CG . PRO A 1 285 ? 23.331 2.826 -1.445 1.00 11.81 ? 317 PRO A CG 1 ATOM 2267 C CD . PRO A 1 285 ? 23.784 1.378 -1.352 1.00 11.79 ? 317 PRO A CD 1 ATOM 2268 N N . ALA A 1 286 ? 21.206 2.358 -4.800 1.00 12.00 ? 318 ALA A N 1 ATOM 2269 C CA . ALA A 1 286 ? 21.233 2.437 -6.250 1.00 11.56 ? 318 ALA A CA 1 ATOM 2270 C C . ALA A 1 286 ? 22.117 3.555 -6.749 1.00 10.84 ? 318 ALA A C 1 ATOM 2271 O O . ALA A 1 286 ? 22.450 4.471 -5.989 1.00 10.14 ? 318 ALA A O 1 ATOM 2272 C CB . ALA A 1 286 ? 19.801 2.657 -6.757 1.00 11.76 ? 318 ALA A CB 1 ATOM 2273 N N . VAL A 1 287 ? 22.470 3.457 -8.038 1.00 10.48 ? 319 VAL A N 1 ATOM 2274 C CA . VAL A 1 287 ? 23.113 4.561 -8.758 1.00 10.38 ? 319 VAL A CA 1 ATOM 2275 C C . VAL A 1 287 ? 22.067 5.586 -9.187 1.00 10.30 ? 319 VAL A C 1 ATOM 2276 O O . VAL A 1 287 ? 22.302 6.811 -9.081 1.00 10.62 ? 319 VAL A O 1 ATOM 2277 C CB . VAL A 1 287 ? 23.933 4.106 -9.994 1.00 10.28 ? 319 VAL A CB 1 ATOM 2278 C CG1 . VAL A 1 287 ? 24.498 5.316 -10.734 1.00 10.14 ? 319 VAL A CG1 1 ATOM 2279 C CG2 . VAL A 1 287 ? 25.085 3.201 -9.577 1.00 10.37 ? 319 VAL A CG2 1 ATOM 2280 N N . THR A 1 288 ? 20.932 5.109 -9.694 1.00 9.87 ? 320 THR A N 1 ATOM 2281 C CA . THR A 1 288 ? 19.867 6.030 -10.036 1.00 9.69 ? 320 THR A CA 1 ATOM 2282 C C . THR A 1 288 ? 19.339 6.695 -8.778 1.00 9.70 ? 320 THR A C 1 ATOM 2283 O O . THR A 1 288 ? 19.181 6.051 -7.763 1.00 9.83 ? 320 THR A O 1 ATOM 2284 C CB . THR A 1 288 ? 18.685 5.359 -10.753 1.00 9.61 ? 320 THR A CB 1 ATOM 2285 O OG1 . THR A 1 288 ? 17.655 6.343 -10.975 1.00 9.48 ? 320 THR A OG1 1 ATOM 2286 C CG2 . THR A 1 288 ? 18.114 4.218 -9.939 1.00 9.55 ? 320 THR A CG2 1 ATOM 2287 N N . PRO A 1 289 ? 19.036 7.977 -8.853 1.00 9.66 ? 321 PRO A N 1 ATOM 2288 C CA . PRO A 1 289 ? 18.380 8.710 -7.806 1.00 10.10 ? 321 PRO A CA 1 ATOM 2289 C C . PRO A 1 289 ? 16.839 8.763 -7.909 1.00 10.99 ? 321 PRO A C 1 ATOM 2290 O O . PRO A 1 289 ? 16.177 9.545 -7.176 1.00 10.82 ? 321 PRO A O 1 ATOM 2291 C CB . PRO A 1 289 ? 18.898 10.115 -8.044 1.00 9.95 ? 321 PRO A CB 1 ATOM 2292 C CG . PRO A 1 289 ? 18.980 10.203 -9.512 1.00 9.79 ? 321 PRO A CG 1 ATOM 2293 C CD . PRO A 1 289 ? 19.319 8.827 -10.006 1.00 9.67 ? 321 PRO A CD 1 ATOM 2294 N N . VAL A 1 290 ? 16.271 7.971 -8.810 1.00 11.87 ? 322 VAL A N 1 ATOM 2295 C CA . VAL A 1 290 ? 14.898 8.198 -9.243 1.00 12.78 ? 322 VAL A CA 1 ATOM 2296 C C . VAL A 1 290 ? 13.905 7.997 -8.082 1.00 13.14 ? 322 VAL A C 1 ATOM 2297 O O . VAL A 1 290 ? 14.178 7.218 -7.161 1.00 14.17 ? 322 VAL A O 1 ATOM 2298 C CB . VAL A 1 290 ? 14.549 7.308 -10.483 1.00 13.32 ? 322 VAL A CB 1 ATOM 2299 C CG1 . VAL A 1 290 ? 14.375 5.844 -10.090 1.00 13.48 ? 322 VAL A CG1 1 ATOM 2300 C CG2 . VAL A 1 290 ? 13.305 7.819 -11.215 1.00 13.48 ? 322 VAL A CG2 1 ATOM 2301 N N . LYS A 1 291 ? 12.791 8.729 -8.116 1.00 12.86 ? 323 LYS A N 1 ATOM 2302 C CA . LYS A 1 291 ? 11.699 8.557 -7.170 1.00 13.03 ? 323 LYS A CA 1 ATOM 2303 C C . LYS A 1 291 ? 10.369 9.086 -7.683 1.00 13.74 ? 323 LYS A C 1 ATOM 2304 O O . LYS A 1 291 ? 10.305 9.786 -8.725 1.00 13.79 ? 323 LYS A O 1 ATOM 2305 C CB . LYS A 1 291 ? 11.999 9.256 -5.878 1.00 12.59 ? 323 LYS A CB 1 ATOM 2306 C CG . LYS A 1 291 ? 12.114 10.746 -6.040 1.00 12.24 ? 323 LYS A CG 1 ATOM 2307 C CD . LYS A 1 291 ? 11.471 11.460 -4.879 1.00 11.98 ? 323 LYS A CD 1 ATOM 2308 C CE . LYS A 1 291 ? 11.531 12.952 -5.079 1.00 11.84 ? 323 LYS A CE 1 ATOM 2309 N NZ . LYS A 1 291 ? 10.289 13.558 -4.549 1.00 12.07 1 323 LYS A NZ 1 ATOM 2310 N N . SER A 1 292 ? 9.312 8.708 -6.957 1.00 14.07 ? 324 SER A N 1 ATOM 2311 C CA A SER A 1 292 ? 7.970 9.182 -7.255 0.50 14.59 ? 324 SER A CA 1 ATOM 2312 C CA B SER A 1 292 ? 7.968 9.180 -7.252 0.50 14.43 ? 324 SER A CA 1 ATOM 2313 C C . SER A 1 292 ? 7.860 10.660 -6.898 1.00 15.06 ? 324 SER A C 1 ATOM 2314 O O . SER A 1 292 ? 8.671 11.205 -6.120 1.00 15.13 ? 324 SER A O 1 ATOM 2315 C CB A SER A 1 292 ? 6.915 8.417 -6.455 0.50 14.74 ? 324 SER A CB 1 ATOM 2316 C CB B SER A 1 292 ? 6.911 8.368 -6.483 0.50 14.40 ? 324 SER A CB 1 ATOM 2317 O OG A SER A 1 292 ? 6.879 7.046 -6.789 0.50 15.02 ? 324 SER A OG 1 ATOM 2318 O OG B SER A 1 292 ? 5.964 9.200 -5.816 0.50 14.24 ? 324 SER A OG 1 ATOM 2319 N N . VAL A 1 293 ? 6.849 11.303 -7.452 1.00 15.55 ? 325 VAL A N 1 ATOM 2320 C CA . VAL A 1 293 ? 6.577 12.669 -7.131 1.00 15.87 ? 325 VAL A CA 1 ATOM 2321 C C . VAL A 1 293 ? 6.096 12.788 -5.687 1.00 16.47 ? 325 VAL A C 1 ATOM 2322 O O . VAL A 1 293 ? 6.473 13.713 -4.988 1.00 17.30 ? 325 VAL A O 1 ATOM 2323 C CB . VAL A 1 293 ? 5.546 13.207 -8.102 1.00 16.15 ? 325 VAL A CB 1 ATOM 2324 C CG1 . VAL A 1 293 ? 4.959 14.519 -7.590 1.00 16.93 ? 325 VAL A CG1 1 ATOM 2325 C CG2 . VAL A 1 293 ? 6.206 13.372 -9.464 1.00 16.23 ? 325 VAL A CG2 1 ATOM 2326 N N . LEU A 1 294 ? 5.302 11.835 -5.220 1.00 16.76 ? 326 LEU A N 1 ATOM 2327 C CA . LEU A 1 294 ? 4.722 11.935 -3.891 1.00 17.32 ? 326 LEU A CA 1 ATOM 2328 C C . LEU A 1 294 ? 5.712 11.617 -2.770 1.00 18.59 ? 326 LEU A C 1 ATOM 2329 O O . LEU A 1 294 ? 5.454 11.912 -1.604 1.00 18.46 ? 326 LEU A O 1 ATOM 2330 C CB . LEU A 1 294 ? 3.502 11.022 -3.803 1.00 17.26 ? 326 LEU A CB 1 ATOM 2331 C CG . LEU A 1 294 ? 2.389 11.380 -4.811 1.00 17.54 ? 326 LEU A CG 1 ATOM 2332 C CD1 . LEU A 1 294 ? 1.086 10.642 -4.590 1.00 17.43 ? 326 LEU A CD1 1 ATOM 2333 C CD2 . LEU A 1 294 ? 2.095 12.870 -4.779 1.00 18.09 ? 326 LEU A CD2 1 ATOM 2334 N N . GLU A 1 295 ? 6.852 11.036 -3.123 1.00 20.17 ? 327 GLU A N 1 ATOM 2335 C CA . GLU A 1 295 ? 7.840 10.634 -2.134 1.00 21.22 ? 327 GLU A CA 1 ATOM 2336 C C . GLU A 1 295 ? 8.724 11.813 -1.701 1.00 21.42 ? 327 GLU A C 1 ATOM 2337 O O . GLU A 1 295 ? 9.308 12.499 -2.517 1.00 21.37 ? 327 GLU A O 1 ATOM 2338 C CB . GLU A 1 295 ? 8.677 9.490 -2.703 1.00 22.15 ? 327 GLU A CB 1 ATOM 2339 C CG . GLU A 1 295 ? 7.914 8.184 -2.832 1.00 23.53 ? 327 GLU A CG 1 ATOM 2340 C CD . GLU A 1 295 ? 8.640 7.128 -3.665 1.00 26.38 ? 327 GLU A CD 1 ATOM 2341 O OE1 . GLU A 1 295 ? 8.025 6.083 -3.999 1.00 29.16 ? 327 GLU A OE1 1 ATOM 2342 O OE2 . GLU A 1 295 ? 9.827 7.326 -4.003 1.00 28.64 -1 327 GLU A OE2 1 ATOM 2343 N N . LYS A 1 296 ? 8.805 12.056 -0.404 1.00 22.58 ? 328 LYS A N 1 ATOM 2344 C CA . LYS A 1 296 ? 9.669 13.105 0.131 1.00 24.01 ? 328 LYS A CA 1 ATOM 2345 C C . LYS A 1 296 ? 11.123 12.825 -0.156 1.00 22.18 ? 328 LYS A C 1 ATOM 2346 O O . LYS A 1 296 ? 11.865 13.694 -0.581 1.00 22.25 ? 328 LYS A O 1 ATOM 2347 C CB . LYS A 1 296 ? 9.494 13.178 1.646 1.00 26.93 ? 328 LYS A CB 1 ATOM 2348 C CG . LYS A 1 296 ? 10.330 14.238 2.342 1.00 30.48 ? 328 LYS A CG 1 ATOM 2349 C CD . LYS A 1 296 ? 9.927 15.658 1.931 1.00 34.56 ? 328 LYS A CD 1 ATOM 2350 C CE . LYS A 1 296 ? 10.690 16.746 2.693 1.00 37.72 ? 328 LYS A CE 1 ATOM 2351 N NZ . LYS A 1 296 ? 12.176 16.514 2.692 1.00 40.57 1 328 LYS A NZ 1 ATOM 2352 N N . GLN A 1 297 ? 11.498 11.582 0.082 1.00 20.82 ? 329 GLN A N 1 ATOM 2353 C CA . GLN A 1 297 ? 12.861 11.139 0.101 1.00 19.68 ? 329 GLN A CA 1 ATOM 2354 C C . GLN A 1 297 ? 13.239 10.350 -1.142 1.00 17.96 ? 329 GLN A C 1 ATOM 2355 O O . GLN A 1 297 ? 12.397 9.788 -1.823 1.00 17.28 ? 329 GLN A O 1 ATOM 2356 C CB . GLN A 1 297 ? 13.003 10.208 1.292 1.00 21.28 ? 329 GLN A CB 1 ATOM 2357 C CG . GLN A 1 297 ? 12.850 10.921 2.609 1.00 22.98 ? 329 GLN A CG 1 ATOM 2358 C CD . GLN A 1 297 ? 13.894 12.002 2.744 1.00 25.44 ? 329 GLN A CD 1 ATOM 2359 O OE1 . GLN A 1 297 ? 13.596 13.181 2.968 1.00 27.77 ? 329 GLN A OE1 1 ATOM 2360 N NE2 . GLN A 1 297 ? 15.141 11.608 2.588 1.00 27.34 ? 329 GLN A NE2 1 ATOM 2361 N N . THR A 1 298 ? 14.533 10.306 -1.415 1.00 16.53 ? 330 THR A N 1 ATOM 2362 C CA . THR A 1 298 ? 15.124 9.301 -2.295 1.00 15.24 ? 330 THR A CA 1 ATOM 2363 C C . THR A 1 298 ? 16.586 9.081 -1.865 1.00 14.41 ? 330 THR A C 1 ATOM 2364 O O . THR A 1 298 ? 17.049 9.650 -0.867 1.00 13.79 ? 330 THR A O 1 ATOM 2365 C CB . THR A 1 298 ? 14.983 9.689 -3.799 1.00 14.79 ? 330 THR A CB 1 ATOM 2366 O OG1 . THR A 1 298 ? 15.330 8.577 -4.647 1.00 14.34 ? 330 THR A OG1 1 ATOM 2367 C CG2 . THR A 1 298 ? 15.841 10.873 -4.138 1.00 14.79 ? 330 THR A CG2 1 ATOM 2368 N N . ASN A 1 299 ? 17.300 8.240 -2.609 1.00 13.94 ? 331 ASN A N 1 ATOM 2369 C CA . ASN A 1 299 ? 18.744 8.088 -2.419 1.00 13.68 ? 331 ASN A CA 1 ATOM 2370 C C . ASN A 1 299 ? 19.535 9.106 -3.243 1.00 13.93 ? 331 ASN A C 1 ATOM 2371 O O . ASN A 1 299 ? 19.009 9.718 -4.159 1.00 14.82 ? 331 ASN A O 1 ATOM 2372 C CB . ASN A 1 299 ? 19.179 6.692 -2.778 1.00 13.28 ? 331 ASN A CB 1 ATOM 2373 C CG . ASN A 1 299 ? 18.852 6.333 -4.204 1.00 13.36 ? 331 ASN A CG 1 ATOM 2374 O OD1 . ASN A 1 299 ? 17.686 6.120 -4.586 1.00 13.60 ? 331 ASN A OD1 1 ATOM 2375 N ND2 . ASN A 1 299 ? 19.886 6.238 -5.009 1.00 13.72 ? 331 ASN A ND2 1 ATOM 2376 N N . ASN A 1 300 ? 20.772 9.375 -2.844 1.00 13.69 ? 332 ASN A N 1 ATOM 2377 C CA . ASN A 1 300 ? 21.755 9.953 -3.748 1.00 12.97 ? 332 ASN A CA 1 ATOM 2378 C C . ASN A 1 300 ? 22.371 8.736 -4.402 1.00 12.87 ? 332 ASN A C 1 ATOM 2379 O O . ASN A 1 300 ? 22.330 7.638 -3.832 1.00 12.31 ? 332 ASN A O 1 ATOM 2380 C CB . ASN A 1 300 ? 22.876 10.708 -3.020 1.00 12.58 ? 332 ASN A CB 1 ATOM 2381 C CG . ASN A 1 300 ? 22.500 12.114 -2.595 1.00 12.13 ? 332 ASN A CG 1 ATOM 2382 O OD1 . ASN A 1 300 ? 22.667 12.472 -1.420 1.00 11.79 ? 332 ASN A OD1 1 ATOM 2383 N ND2 . ASN A 1 300 ? 22.052 12.935 -3.541 1.00 11.93 ? 332 ASN A ND2 1 ATOM 2384 N N . PRO A 1 301 ? 22.973 8.923 -5.579 1.00 13.02 ? 333 PRO A N 1 ATOM 2385 C CA . PRO A 1 301 ? 23.626 7.809 -6.237 1.00 13.17 ? 333 PRO A CA 1 ATOM 2386 C C . PRO A 1 301 ? 24.722 7.278 -5.348 1.00 13.49 ? 333 PRO A C 1 ATOM 2387 O O . PRO A 1 301 ? 25.311 8.035 -4.590 1.00 13.21 ? 333 PRO A O 1 ATOM 2388 C CB . PRO A 1 301 ? 24.206 8.443 -7.495 1.00 13.12 ? 333 PRO A CB 1 ATOM 2389 C CG . PRO A 1 301 ? 23.313 9.596 -7.767 1.00 13.16 ? 333 PRO A CG 1 ATOM 2390 C CD . PRO A 1 301 ? 23.014 10.139 -6.403 1.00 13.07 ? 333 PRO A CD 1 ATOM 2391 N N . GLY A 1 302 ? 24.975 5.983 -5.437 1.00 14.14 ? 334 GLY A N 1 ATOM 2392 C CA . GLY A 1 302 ? 25.931 5.352 -4.571 1.00 14.85 ? 334 GLY A CA 1 ATOM 2393 C C . GLY A 1 302 ? 26.591 4.141 -5.192 1.00 15.67 ? 334 GLY A C 1 ATOM 2394 O O . GLY A 1 302 ? 26.039 3.475 -6.076 1.00 15.36 ? 334 GLY A O 1 ATOM 2395 N N . ILE A 1 303 ? 27.763 3.859 -4.641 1.00 16.46 ? 335 ILE A N 1 ATOM 2396 C CA . ILE A 1 303 ? 28.756 2.964 -5.175 1.00 17.14 ? 335 ILE A CA 1 ATOM 2397 C C . ILE A 1 303 ? 29.457 2.525 -3.917 1.00 16.97 ? 335 ILE A C 1 ATOM 2398 O O . ILE A 1 303 ? 29.655 3.346 -3.017 1.00 16.87 ? 335 ILE A O 1 ATOM 2399 C CB . ILE A 1 303 ? 29.676 3.793 -6.113 1.00 18.60 ? 335 ILE A CB 1 ATOM 2400 C CG1 . ILE A 1 303 ? 29.037 3.877 -7.486 1.00 20.22 ? 335 ILE A CG1 1 ATOM 2401 C CG2 . ILE A 1 303 ? 31.087 3.253 -6.273 1.00 18.64 ? 335 ILE A CG2 1 ATOM 2402 C CD1 . ILE A 1 303 ? 28.530 2.530 -8.009 1.00 20.75 ? 335 ILE A CD1 1 ATOM 2403 N N . ARG A 1 304 ? 29.784 1.249 -3.800 1.00 16.76 ? 336 ARG A N 1 ATOM 2404 C CA . ARG A 1 304 ? 30.427 0.801 -2.597 1.00 17.14 ? 336 ARG A CA 1 ATOM 2405 C C . ARG A 1 304 ? 31.468 -0.249 -2.867 1.00 18.94 ? 336 ARG A C 1 ATOM 2406 O O . ARG A 1 304 ? 31.394 -0.999 -3.853 1.00 20.34 ? 336 ARG A O 1 ATOM 2407 C CB . ARG A 1 304 ? 29.400 0.297 -1.582 1.00 16.60 ? 336 ARG A CB 1 ATOM 2408 C CG . ARG A 1 304 ? 28.656 -0.955 -1.996 1.00 16.50 ? 336 ARG A CG 1 ATOM 2409 C CD . ARG A 1 304 ? 27.909 -1.635 -0.843 1.00 16.28 ? 336 ARG A CD 1 ATOM 2410 N NE . ARG A 1 304 ? 27.053 -0.709 -0.103 1.00 16.17 ? 336 ARG A NE 1 ATOM 2411 C CZ . ARG A 1 304 ? 26.087 -1.062 0.746 1.00 16.51 ? 336 ARG A CZ 1 ATOM 2412 N NH1 . ARG A 1 304 ? 25.785 -2.336 0.980 1.00 17.29 1 336 ARG A NH1 1 ATOM 2413 N NH2 . ARG A 1 304 ? 25.394 -0.122 1.367 1.00 16.39 ? 336 ARG A NH2 1 ATOM 2414 N N . LEU A 1 305 ? 32.413 -0.308 -1.936 1.00 20.27 ? 337 LEU A N 1 ATOM 2415 C CA . LEU A 1 305 ? 33.564 -1.164 -1.993 1.00 21.03 ? 337 LEU A CA 1 ATOM 2416 C C . LEU A 1 305 ? 33.661 -1.950 -0.692 1.00 21.38 ? 337 LEU A C 1 ATOM 2417 O O . LEU A 1 305 ? 33.677 -1.363 0.410 1.00 21.48 ? 337 LEU A O 1 ATOM 2418 C CB . LEU A 1 305 ? 34.775 -0.271 -2.128 1.00 23.19 ? 337 LEU A CB 1 ATOM 2419 C CG . LEU A 1 305 ? 36.145 -0.913 -1.953 1.00 25.41 ? 337 LEU A CG 1 ATOM 2420 C CD1 . LEU A 1 305 ? 36.314 -1.997 -3.014 1.00 26.92 ? 337 LEU A CD1 1 ATOM 2421 C CD2 . LEU A 1 305 ? 37.243 0.143 -2.043 1.00 25.59 ? 337 LEU A CD2 1 ATOM 2422 N N . PHE A 1 306 ? 33.725 -3.274 -0.822 1.00 21.66 ? 338 PHE A N 1 ATOM 2423 C CA . PHE A 1 306 ? 33.960 -4.184 0.312 1.00 21.83 ? 338 PHE A CA 1 ATOM 2424 C C . PHE A 1 306 ? 35.423 -4.615 0.486 1.00 24.10 ? 338 PHE A C 1 ATOM 2425 O O . PHE A 1 306 ? 36.232 -4.579 -0.462 1.00 25.31 ? 338 PHE A O 1 ATOM 2426 C CB . PHE A 1 306 ? 33.130 -5.435 0.150 1.00 20.51 ? 338 PHE A CB 1 ATOM 2427 C CG . PHE A 1 306 ? 31.713 -5.240 0.513 1.00 19.97 ? 338 PHE A CG 1 ATOM 2428 C CD1 . PHE A 1 306 ? 31.341 -5.189 1.835 1.00 19.75 ? 338 PHE A CD1 1 ATOM 2429 C CD2 . PHE A 1 306 ? 30.748 -5.101 -0.458 1.00 19.67 ? 338 PHE A CD2 1 ATOM 2430 C CE1 . PHE A 1 306 ? 30.017 -5.026 2.188 1.00 19.45 ? 338 PHE A CE1 1 ATOM 2431 C CE2 . PHE A 1 306 ? 29.429 -4.928 -0.119 1.00 19.23 ? 338 PHE A CE2 1 ATOM 2432 C CZ . PHE A 1 306 ? 29.065 -4.891 1.208 1.00 19.62 ? 338 PHE A CZ 1 ATOM 2433 N N . GLN A 1 307 ? 35.742 -5.039 1.712 1.00 24.80 ? 339 GLN A N 1 ATOM 2434 C CA . GLN A 1 307 ? 37.070 -5.517 2.062 1.00 24.02 ? 339 GLN A CA 1 ATOM 2435 C C . GLN A 1 307 ? 36.985 -6.892 2.677 1.00 25.78 ? 339 GLN A C 1 ATOM 2436 O O . GLN A 1 307 ? 36.133 -7.157 3.521 1.00 27.15 ? 339 GLN A O 1 ATOM 2437 C CB . GLN A 1 307 ? 37.712 -4.557 3.037 1.00 23.05 ? 339 GLN A CB 1 ATOM 2438 C CG . GLN A 1 307 ? 38.067 -3.233 2.387 1.00 23.01 ? 339 GLN A CG 1 ATOM 2439 C CD . GLN A 1 307 ? 38.817 -2.329 3.318 1.00 22.76 ? 339 GLN A CD 1 ATOM 2440 O OE1 . GLN A 1 307 ? 38.887 -2.591 4.501 1.00 23.95 ? 339 GLN A OE1 1 ATOM 2441 N NE2 . GLN A 1 307 ? 39.363 -1.251 2.798 1.00 22.65 ? 339 GLN A NE2 1 ATOM 2442 N N . TYR A 1 308 ? 37.875 -7.778 2.273 1.00 27.97 ? 340 TYR A N 1 ATOM 2443 C CA . TYR A 1 308 ? 37.883 -9.100 2.857 1.00 29.03 ? 340 TYR A CA 1 ATOM 2444 C C . TYR A 1 308 ? 39.270 -9.607 3.213 1.00 29.30 ? 340 TYR A C 1 ATOM 2445 O O . TYR A 1 308 ? 40.296 -9.028 2.845 1.00 27.59 ? 340 TYR A O 1 ATOM 2446 C CB . TYR A 1 308 ? 37.182 -10.077 1.937 1.00 30.08 ? 340 TYR A CB 1 ATOM 2447 C CG . TYR A 1 308 ? 37.784 -10.200 0.561 1.00 31.76 ? 340 TYR A CG 1 ATOM 2448 C CD1 . TYR A 1 308 ? 37.581 -9.221 -0.392 1.00 33.22 ? 340 TYR A CD1 1 ATOM 2449 C CD2 . TYR A 1 308 ? 38.522 -11.317 0.200 1.00 33.75 ? 340 TYR A CD2 1 ATOM 2450 C CE1 . TYR A 1 308 ? 38.103 -9.334 -1.670 1.00 34.11 ? 340 TYR A CE1 1 ATOM 2451 C CE2 . TYR A 1 308 ? 39.046 -11.448 -1.075 1.00 34.79 ? 340 TYR A CE2 1 ATOM 2452 C CZ . TYR A 1 308 ? 38.834 -10.448 -2.014 1.00 35.03 ? 340 TYR A CZ 1 ATOM 2453 O OH . TYR A 1 308 ? 39.342 -10.555 -3.298 1.00 34.51 ? 340 TYR A OH 1 ATOM 2454 N N . ASP A 1 309 ? 39.255 -10.682 3.986 1.00 30.78 ? 341 ASP A N 1 ATOM 2455 C CA . ASP A 1 309 ? 40.438 -11.401 4.366 1.00 33.26 ? 341 ASP A CA 1 ATOM 2456 C C . ASP A 1 309 ? 40.559 -12.516 3.357 1.00 31.51 ? 341 ASP A C 1 ATOM 2457 O O . ASP A 1 309 ? 39.664 -13.375 3.287 1.00 32.97 ? 341 ASP A O 1 ATOM 2458 C CB . ASP A 1 309 ? 40.271 -11.981 5.771 1.00 37.81 ? 341 ASP A CB 1 ATOM 2459 C CG . ASP A 1 309 ? 41.595 -12.359 6.425 1.00 42.31 ? 341 ASP A CG 1 ATOM 2460 O OD1 . ASP A 1 309 ? 42.664 -11.994 5.881 1.00 48.90 ? 341 ASP A OD1 1 ATOM 2461 O OD2 . ASP A 1 309 ? 41.564 -13.000 7.504 1.00 44.81 -1 341 ASP A OD2 1 ATOM 2462 N N . PRO A 1 310 ? 41.645 -12.515 2.562 1.00 28.81 ? 342 PRO A N 1 ATOM 2463 C CA . PRO A 1 310 ? 41.845 -13.500 1.500 1.00 29.21 ? 342 PRO A CA 1 ATOM 2464 C C . PRO A 1 310 ? 41.924 -14.969 1.928 1.00 29.58 ? 342 PRO A C 1 ATOM 2465 O O . PRO A 1 310 ? 41.807 -15.867 1.088 1.00 29.92 ? 342 PRO A O 1 ATOM 2466 C CB . PRO A 1 310 ? 43.155 -13.050 0.868 1.00 28.60 ? 342 PRO A CB 1 ATOM 2467 C CG . PRO A 1 310 ? 43.166 -11.581 1.071 1.00 28.27 ? 342 PRO A CG 1 ATOM 2468 C CD . PRO A 1 310 ? 42.624 -11.425 2.453 1.00 28.81 ? 342 PRO A CD 1 ATOM 2469 N N . ARG A 1 311 ? 42.093 -15.203 3.218 1.00 31.04 ? 343 ARG A N 1 ATOM 2470 C CA . ARG A 1 311 ? 42.197 -16.542 3.753 1.00 31.78 ? 343 ARG A CA 1 ATOM 2471 C C . ARG A 1 311 ? 40.831 -17.202 3.855 1.00 31.92 ? 343 ARG A C 1 ATOM 2472 O O . ARG A 1 311 ? 40.628 -18.244 3.262 1.00 33.26 ? 343 ARG A O 1 ATOM 2473 C CB . ARG A 1 311 ? 42.888 -16.486 5.109 1.00 33.43 ? 343 ARG A CB 1 ATOM 2474 C CG . ARG A 1 311 ? 44.291 -15.899 5.011 1.00 36.70 ? 343 ARG A CG 1 ATOM 2475 C CD . ARG A 1 311 ? 44.956 -15.722 6.367 1.00 39.67 ? 343 ARG A CD 1 ATOM 2476 N NE . ARG A 1 311 ? 44.651 -14.430 6.974 1.00 41.53 ? 343 ARG A NE 1 ATOM 2477 C CZ . ARG A 1 311 ? 44.836 -14.128 8.258 1.00 43.06 ? 343 ARG A CZ 1 ATOM 2478 N NH1 . ARG A 1 311 ? 45.334 -15.028 9.102 1.00 46.10 1 343 ARG A NH1 1 ATOM 2479 N NH2 . ARG A 1 311 ? 44.510 -12.918 8.701 1.00 42.30 ? 343 ARG A NH2 1 ATOM 2480 N N . ASP A 1 312 ? 39.897 -16.587 4.582 1.00 32.38 ? 344 ASP A N 1 ATOM 2481 C CA . ASP A 1 312 ? 38.554 -17.163 4.832 1.00 31.56 ? 344 ASP A CA 1 ATOM 2482 C C . ASP A 1 312 ? 37.432 -16.354 4.179 1.00 30.06 ? 344 ASP A C 1 ATOM 2483 O O . ASP A 1 312 ? 36.251 -16.694 4.329 1.00 27.54 ? 344 ASP A O 1 ATOM 2484 C CB . ASP A 1 312 ? 38.271 -17.347 6.346 1.00 32.47 ? 344 ASP A CB 1 ATOM 2485 C CG . ASP A 1 312 ? 38.827 -16.191 7.235 1.00 34.78 ? 344 ASP A CG 1 ATOM 2486 O OD1 . ASP A 1 312 ? 39.372 -15.185 6.707 1.00 36.06 ? 344 ASP A OD1 1 ATOM 2487 O OD2 . ASP A 1 312 ? 38.740 -16.301 8.484 1.00 36.03 -1 344 ASP A OD2 1 ATOM 2488 N N . TYR A 1 313 ? 37.807 -15.298 3.451 1.00 29.77 ? 345 TYR A N 1 ATOM 2489 C CA . TYR A 1 313 ? 36.829 -14.400 2.795 1.00 31.89 ? 345 TYR A CA 1 ATOM 2490 C C . TYR A 1 313 ? 35.860 -13.782 3.796 1.00 31.42 ? 345 TYR A C 1 ATOM 2491 O O . TYR A 1 313 ? 34.706 -13.503 3.489 1.00 29.16 ? 345 TYR A O 1 ATOM 2492 C CB . TYR A 1 313 ? 36.108 -15.135 1.638 1.00 32.52 ? 345 TYR A CB 1 ATOM 2493 C CG . TYR A 1 313 ? 37.145 -15.700 0.717 1.00 32.28 ? 345 TYR A CG 1 ATOM 2494 C CD1 . TYR A 1 313 ? 37.940 -14.847 -0.051 1.00 31.85 ? 345 TYR A CD1 1 ATOM 2495 C CD2 . TYR A 1 313 ? 37.414 -17.060 0.698 1.00 32.45 ? 345 TYR A CD2 1 ATOM 2496 C CE1 . TYR A 1 313 ? 38.945 -15.336 -0.846 1.00 32.68 ? 345 TYR A CE1 1 ATOM 2497 C CE2 . TYR A 1 313 ? 38.419 -17.569 -0.098 1.00 33.28 ? 345 TYR A CE2 1 ATOM 2498 C CZ . TYR A 1 313 ? 39.183 -16.701 -0.859 1.00 34.65 ? 345 TYR A CZ 1 ATOM 2499 O OH . TYR A 1 313 ? 40.187 -17.205 -1.650 1.00 39.81 ? 345 TYR A OH 1 ATOM 2500 N N . LYS A 1 314 ? 36.381 -13.577 4.998 1.00 32.19 ? 346 LYS A N 1 ATOM 2501 C CA . LYS A 1 314 ? 35.689 -12.922 6.086 1.00 33.24 ? 346 LYS A CA 1 ATOM 2502 C C . LYS A 1 314 ? 35.622 -11.448 5.725 1.00 30.26 ? 346 LYS A C 1 ATOM 2503 O O . LYS A 1 314 ? 36.547 -10.919 5.114 1.00 29.24 ? 346 LYS A O 1 ATOM 2504 C CB . LYS A 1 314 ? 36.483 -13.168 7.378 1.00 37.47 ? 346 LYS A CB 1 ATOM 2505 C CG . LYS A 1 314 ? 36.121 -12.343 8.603 1.00 42.87 ? 346 LYS A CG 1 ATOM 2506 C CD . LYS A 1 314 ? 36.767 -12.951 9.860 1.00 46.62 ? 346 LYS A CD 1 ATOM 2507 C CE . LYS A 1 314 ? 36.526 -12.105 11.111 1.00 49.01 ? 346 LYS A CE 1 ATOM 2508 N NZ . LYS A 1 314 ? 37.458 -10.943 11.189 1.00 51.29 1 346 LYS A NZ 1 ATOM 2509 N N . LEU A 1 315 ? 34.514 -10.801 6.067 1.00 28.03 ? 347 LEU A N 1 ATOM 2510 C CA . LEU A 1 315 ? 34.266 -9.417 5.646 1.00 26.41 ? 347 LEU A CA 1 ATOM 2511 C C . LEU A 1 315 ? 34.837 -8.392 6.611 1.00 25.49 ? 347 LEU A C 1 ATOM 2512 O O . LEU A 1 315 ? 34.413 -8.284 7.741 1.00 26.87 ? 347 LEU A O 1 ATOM 2513 C CB . LEU A 1 315 ? 32.764 -9.202 5.460 1.00 24.93 ? 347 LEU A CB 1 ATOM 2514 C CG . LEU A 1 315 ? 32.291 -9.779 4.141 1.00 24.10 ? 347 LEU A CG 1 ATOM 2515 C CD1 . LEU A 1 315 ? 30.776 -9.773 4.068 1.00 24.08 ? 347 LEU A CD1 1 ATOM 2516 C CD2 . LEU A 1 315 ? 32.909 -8.999 2.986 1.00 23.70 ? 347 LEU A CD2 1 ATOM 2517 N N . LEU A 1 316 ? 35.799 -7.620 6.174 1.00 25.00 ? 348 LEU A N 1 ATOM 2518 C CA . LEU A 1 316 ? 36.474 -6.773 7.122 1.00 26.48 ? 348 LEU A CA 1 ATOM 2519 C C . LEU A 1 316 ? 35.803 -5.457 7.255 1.00 25.87 ? 348 LEU A C 1 ATOM 2520 O O . LEU A 1 316 ? 35.773 -4.910 8.344 1.00 28.07 ? 348 LEU A O 1 ATOM 2521 C CB . LEU A 1 316 ? 37.935 -6.578 6.734 1.00 27.98 ? 348 LEU A CB 1 ATOM 2522 C CG . LEU A 1 316 ? 38.649 -7.934 6.805 1.00 29.92 ? 348 LEU A CG 1 ATOM 2523 C CD1 . LEU A 1 316 ? 40.076 -7.824 6.298 1.00 30.69 ? 348 LEU A CD1 1 ATOM 2524 C CD2 . LEU A 1 316 ? 38.595 -8.535 8.214 1.00 30.43 ? 348 LEU A CD2 1 ATOM 2525 N N . ASP A 1 317 ? 35.286 -4.929 6.154 1.00 24.48 ? 349 ASP A N 1 ATOM 2526 C CA . ASP A 1 317 ? 34.702 -3.596 6.162 1.00 22.73 ? 349 ASP A CA 1 ATOM 2527 C C . ASP A 1 317 ? 33.989 -3.243 4.848 1.00 21.86 ? 349 ASP A C 1 ATOM 2528 O O . ASP A 1 317 ? 34.046 -3.996 3.864 1.00 22.48 ? 349 ASP A O 1 ATOM 2529 C CB . ASP A 1 317 ? 35.798 -2.571 6.440 1.00 21.92 ? 349 ASP A CB 1 ATOM 2530 C CG . ASP A 1 317 ? 35.302 -1.411 7.253 1.00 21.83 ? 349 ASP A CG 1 ATOM 2531 O OD1 . ASP A 1 317 ? 34.201 -0.902 6.987 1.00 21.57 ? 349 ASP A OD1 1 ATOM 2532 O OD2 . ASP A 1 317 ? 36.017 -0.983 8.165 1.00 22.60 -1 349 ASP A OD2 1 ATOM 2533 N N . MET A 1 318 ? 33.320 -2.096 4.846 1.00 20.38 ? 350 MET A N 1 ATOM 2534 C CA . MET A 1 318 ? 32.700 -1.565 3.653 1.00 20.20 ? 350 MET A CA 1 ATOM 2535 C C . MET A 1 318 ? 32.782 -0.052 3.612 1.00 19.71 ? 350 MET A C 1 ATOM 2536 O O . MET A 1 318 ? 32.572 0.639 4.614 1.00 18.57 ? 350 MET A O 1 ATOM 2537 C CB . MET A 1 318 ? 31.250 -1.989 3.610 1.00 21.72 ? 350 MET A CB 1 ATOM 2538 C CG . MET A 1 318 ? 30.533 -1.549 2.347 1.00 23.12 ? 350 MET A CG 1 ATOM 2539 S SD . MET A 1 318 ? 29.415 -0.196 2.684 1.00 24.48 ? 350 MET A SD 1 ATOM 2540 C CE . MET A 1 318 ? 28.040 -1.173 3.272 1.00 24.24 ? 350 MET A CE 1 ATOM 2541 N N . LEU A 1 319 ? 33.109 0.469 2.440 1.00 19.71 ? 351 LEU A N 1 ATOM 2542 C CA . LEU A 1 319 ? 33.227 1.913 2.269 1.00 19.55 ? 351 LEU A CA 1 ATOM 2543 C C . LEU A 1 319 ? 32.129 2.265 1.306 1.00 19.48 ? 351 LEU A C 1 ATOM 2544 O O . LEU A 1 319 ? 31.945 1.572 0.306 1.00 20.20 ? 351 LEU A O 1 ATOM 2545 C CB . LEU A 1 319 ? 34.580 2.302 1.684 1.00 19.76 ? 351 LEU A CB 1 ATOM 2546 C CG . LEU A 1 319 ? 35.836 1.885 2.464 1.00 20.31 ? 351 LEU A CG 1 ATOM 2547 C CD1 . LEU A 1 319 ? 36.262 0.431 2.187 1.00 20.02 ? 351 LEU A CD1 1 ATOM 2548 C CD2 . LEU A 1 319 ? 36.955 2.859 2.112 1.00 20.40 ? 351 LEU A CD2 1 ATOM 2549 N N . GLN A 1 320 ? 31.381 3.316 1.613 1.00 18.64 ? 352 GLN A N 1 ATOM 2550 C CA . GLN A 1 320 ? 30.242 3.673 0.814 1.00 17.95 ? 352 GLN A CA 1 ATOM 2551 C C . GLN A 1 320 ? 30.543 4.983 0.228 1.00 16.57 ? 352 GLN A C 1 ATOM 2552 O O . GLN A 1 320 ? 30.737 5.938 0.952 1.00 15.99 ? 352 GLN A O 1 ATOM 2553 C CB . GLN A 1 320 ? 28.988 3.801 1.664 1.00 19.23 ? 352 GLN A CB 1 ATOM 2554 C CG . GLN A 1 320 ? 27.755 4.185 0.852 1.00 20.35 ? 352 GLN A CG 1 ATOM 2555 C CD . GLN A 1 320 ? 27.250 3.052 -0.024 1.00 21.38 ? 352 GLN A CD 1 ATOM 2556 O OE1 . GLN A 1 320 ? 27.039 1.939 0.467 1.00 22.75 ? 352 GLN A OE1 1 ATOM 2557 N NE2 . GLN A 1 320 ? 27.041 3.321 -1.319 1.00 21.81 ? 352 GLN A NE2 1 ATOM 2558 N N . TYR A 1 321 ? 30.561 5.025 -1.094 1.00 16.37 ? 353 TYR A N 1 ATOM 2559 C CA . TYR A 1 321 ? 30.786 6.257 -1.832 1.00 15.89 ? 353 TYR A CA 1 ATOM 2560 C C . TYR A 1 321 ? 29.468 6.735 -2.376 1.00 15.77 ? 353 TYR A C 1 ATOM 2561 O O . TYR A 1 321 ? 28.533 5.940 -2.533 1.00 15.21 ? 353 TYR A O 1 ATOM 2562 C CB . TYR A 1 321 ? 31.753 6.010 -2.977 1.00 15.41 ? 353 TYR A CB 1 ATOM 2563 C CG . TYR A 1 321 ? 33.116 5.570 -2.535 1.00 15.43 ? 353 TYR A CG 1 ATOM 2564 C CD1 . TYR A 1 321 ? 34.067 6.492 -2.140 1.00 15.46 ? 353 TYR A CD1 1 ATOM 2565 C CD2 . TYR A 1 321 ? 33.453 4.220 -2.515 1.00 15.77 ? 353 TYR A CD2 1 ATOM 2566 C CE1 . TYR A 1 321 ? 35.333 6.083 -1.745 1.00 15.87 ? 353 TYR A CE1 1 ATOM 2567 C CE2 . TYR A 1 321 ? 34.715 3.794 -2.130 1.00 16.26 ? 353 TYR A CE2 1 ATOM 2568 C CZ . TYR A 1 321 ? 35.659 4.728 -1.739 1.00 16.38 ? 353 TYR A CZ 1 ATOM 2569 O OH . TYR A 1 321 ? 36.915 4.295 -1.333 1.00 16.82 ? 353 TYR A OH 1 ATOM 2570 N N . TYR A 1 322 ? 29.403 8.032 -2.677 1.00 16.28 ? 354 TYR A N 1 ATOM 2571 C CA . TYR A 1 322 ? 28.169 8.654 -3.179 1.00 16.46 ? 354 TYR A CA 1 ATOM 2572 C C . TYR A 1 322 ? 28.364 9.936 -3.950 1.00 16.48 ? 354 TYR A C 1 ATOM 2573 O O . TYR A 1 322 ? 29.452 10.483 -3.959 1.00 16.16 ? 354 TYR A O 1 ATOM 2574 C CB . TYR A 1 322 ? 27.238 8.944 -2.015 1.00 16.67 ? 354 TYR A CB 1 ATOM 2575 C CG . TYR A 1 322 ? 27.479 10.231 -1.255 1.00 16.90 ? 354 TYR A CG 1 ATOM 2576 C CD1 . TYR A 1 322 ? 28.537 10.362 -0.373 1.00 17.58 ? 354 TYR A CD1 1 ATOM 2577 C CD2 . TYR A 1 322 ? 26.599 11.291 -1.369 1.00 17.12 ? 354 TYR A CD2 1 ATOM 2578 C CE1 . TYR A 1 322 ? 28.709 11.532 0.349 1.00 17.97 ? 354 TYR A CE1 1 ATOM 2579 C CE2 . TYR A 1 322 ? 26.767 12.458 -0.655 1.00 17.07 ? 354 TYR A CE2 1 ATOM 2580 C CZ . TYR A 1 322 ? 27.818 12.576 0.193 1.00 17.47 ? 354 TYR A CZ 1 ATOM 2581 O OH . TYR A 1 322 ? 27.984 13.741 0.878 1.00 18.05 ? 354 TYR A OH 1 ATOM 2582 N N . LEU A 1 323 ? 27.284 10.413 -4.570 1.00 17.19 ? 355 LEU A N 1 ATOM 2583 C CA . LEU A 1 323 ? 27.283 11.671 -5.320 1.00 18.03 ? 355 LEU A CA 1 ATOM 2584 C C . LEU A 1 323 ? 26.265 12.619 -4.704 1.00 18.68 ? 355 LEU A C 1 ATOM 2585 O O . LEU A 1 323 ? 25.108 12.238 -4.613 1.00 18.29 ? 355 LEU A O 1 ATOM 2586 C CB . LEU A 1 323 ? 26.927 11.402 -6.784 1.00 18.20 ? 355 LEU A CB 1 ATOM 2587 C CG . LEU A 1 323 ? 27.041 12.596 -7.747 1.00 18.74 ? 355 LEU A CG 1 ATOM 2588 C CD1 . LEU A 1 323 ? 28.490 12.980 -7.929 1.00 19.14 ? 355 LEU A CD1 1 ATOM 2589 C CD2 . LEU A 1 323 ? 26.491 12.272 -9.124 1.00 18.88 ? 355 LEU A CD2 1 ATOM 2590 N N . ASN A 1 324 ? 26.647 13.827 -4.293 1.00 20.19 ? 356 ASN A N 1 ATOM 2591 C CA . ASN A 1 324 ? 25.711 14.811 -3.784 1.00 20.70 ? 356 ASN A CA 1 ATOM 2592 C C . ASN A 1 324 ? 25.242 15.401 -5.061 1.00 20.90 ? 356 ASN A C 1 ATOM 2593 O O . ASN A 1 324 ? 25.836 16.295 -5.581 1.00 20.82 ? 356 ASN A O 1 ATOM 2594 C CB . ASN A 1 324 ? 26.365 15.862 -2.910 1.00 21.49 ? 356 ASN A CB 1 ATOM 2595 C CG . ASN A 1 324 ? 25.403 16.900 -2.468 1.00 23.31 ? 356 ASN A CG 1 ATOM 2596 O OD1 . ASN A 1 324 ? 24.461 17.116 -3.133 1.00 24.91 ? 356 ASN A OD1 1 ATOM 2597 N ND2 . ASN A 1 324 ? 25.616 17.513 -1.341 1.00 25.76 ? 356 ASN A ND2 1 ATOM 2598 N N . LEU A 1 325 ? 24.152 14.869 -5.562 1.00 20.97 ? 357 LEU A N 1 ATOM 2599 C CA . LEU A 1 325 ? 23.570 15.174 -6.872 1.00 20.42 ? 357 LEU A CA 1 ATOM 2600 C C . LEU A 1 325 ? 23.281 16.635 -7.030 1.00 19.60 ? 357 LEU A C 1 ATOM 2601 O O . LEU A 1 325 ? 23.661 17.236 -7.999 1.00 18.61 ? 357 LEU A O 1 ATOM 2602 C CB . LEU A 1 325 ? 22.261 14.398 -7.050 1.00 21.16 ? 357 LEU A CB 1 ATOM 2603 C CG . LEU A 1 325 ? 21.526 14.507 -8.393 1.00 21.34 ? 357 LEU A CG 1 ATOM 2604 C CD1 . LEU A 1 325 ? 22.448 14.115 -9.530 1.00 21.71 ? 357 LEU A CD1 1 ATOM 2605 C CD2 . LEU A 1 325 ? 20.284 13.629 -8.400 1.00 21.03 ? 357 LEU A CD2 1 ATOM 2606 N N . THR A 1 326 ? 22.600 17.210 -6.062 1.00 20.14 ? 358 THR A N 1 ATOM 2607 C CA . THR A 1 326 ? 22.359 18.611 -6.127 1.00 21.27 ? 358 THR A CA 1 ATOM 2608 C C . THR A 1 326 ? 23.611 19.390 -6.339 1.00 23.30 ? 358 THR A C 1 ATOM 2609 O O . THR A 1 326 ? 23.620 20.286 -7.155 1.00 23.23 ? 358 THR A O 1 ATOM 2610 C CB . THR A 1 326 ? 21.735 19.112 -4.862 1.00 20.96 ? 358 THR A CB 1 ATOM 2611 O OG1 . THR A 1 326 ? 20.367 18.757 -4.920 1.00 20.76 ? 358 THR A OG1 1 ATOM 2612 C CG2 . THR A 1 326 ? 21.848 20.624 -4.780 1.00 21.10 ? 358 THR A CG2 1 ATOM 2613 N N . GLU A 1 327 ? 24.642 19.086 -5.566 1.00 27.29 ? 359 GLU A N 1 ATOM 2614 C CA . GLU A 1 327 ? 25.901 19.812 -5.655 1.00 32.33 ? 359 GLU A CA 1 ATOM 2615 C C . GLU A 1 327 ? 26.470 19.527 -7.019 1.00 30.61 ? 359 GLU A C 1 ATOM 2616 O O . GLU A 1 327 ? 26.795 20.441 -7.770 1.00 30.84 ? 359 GLU A O 1 ATOM 2617 C CB . GLU A 1 327 ? 26.886 19.367 -4.559 1.00 38.73 ? 359 GLU A CB 1 ATOM 2618 C CG . GLU A 1 327 ? 28.250 20.053 -4.591 1.00 43.39 ? 359 GLU A CG 1 ATOM 2619 C CD . GLU A 1 327 ? 29.279 19.388 -3.671 1.00 50.63 ? 359 GLU A CD 1 ATOM 2620 O OE1 . GLU A 1 327 ? 29.653 18.208 -3.895 1.00 52.76 ? 359 GLU A OE1 1 ATOM 2621 O OE2 . GLU A 1 327 ? 29.737 20.057 -2.717 1.00 55.71 -1 359 GLU A OE2 1 ATOM 2622 N N . ALA A 1 328 ? 26.557 18.245 -7.340 1.00 28.73 ? 360 ALA A N 1 ATOM 2623 C CA . ALA A 1 328 ? 27.094 17.809 -8.617 1.00 28.32 ? 360 ALA A CA 1 ATOM 2624 C C . ALA A 1 328 ? 26.442 18.504 -9.781 1.00 27.69 ? 360 ALA A C 1 ATOM 2625 O O . ALA A 1 328 ? 27.091 18.756 -10.762 1.00 27.65 ? 360 ALA A O 1 ATOM 2626 C CB . ALA A 1 328 ? 26.936 16.308 -8.770 1.00 29.24 ? 360 ALA A CB 1 ATOM 2627 N N . ASN A 1 329 ? 25.154 18.800 -9.688 1.00 28.44 ? 361 ASN A N 1 ATOM 2628 C CA . ASN A 1 329 ? 24.517 19.600 -10.722 1.00 28.84 ? 361 ASN A CA 1 ATOM 2629 C C . ASN A 1 329 ? 24.854 21.088 -10.595 1.00 30.84 ? 361 ASN A C 1 ATOM 2630 O O . ASN A 1 329 ? 25.215 21.688 -11.576 1.00 33.57 ? 361 ASN A O 1 ATOM 2631 C CB . ASN A 1 329 ? 23.016 19.326 -10.814 1.00 27.68 ? 361 ASN A CB 1 ATOM 2632 C CG . ASN A 1 329 ? 22.706 17.979 -11.478 1.00 28.06 ? 361 ASN A CG 1 ATOM 2633 O OD1 . ASN A 1 329 ? 23.528 17.388 -12.206 1.00 26.27 ? 361 ASN A OD1 1 ATOM 2634 N ND2 . ASN A 1 329 ? 21.510 17.485 -11.228 1.00 28.42 ? 361 ASN A ND2 1 ATOM 2635 N N . LEU A 1 330 ? 24.823 21.675 -9.404 1.00 34.35 ? 362 LEU A N 1 ATOM 2636 C CA . LEU A 1 330 ? 25.264 23.084 -9.216 1.00 35.50 ? 362 LEU A CA 1 ATOM 2637 C C . LEU A 1 330 ? 26.636 23.378 -9.789 1.00 37.13 ? 362 LEU A C 1 ATOM 2638 O O . LEU A 1 330 ? 26.853 24.393 -10.437 1.00 39.16 ? 362 LEU A O 1 ATOM 2639 C CB . LEU A 1 330 ? 25.302 23.460 -7.730 1.00 35.59 ? 362 LEU A CB 1 ATOM 2640 C CG . LEU A 1 330 ? 23.941 23.847 -7.146 1.00 36.77 ? 362 LEU A CG 1 ATOM 2641 C CD1 . LEU A 1 330 ? 24.030 24.145 -5.653 1.00 36.98 ? 362 LEU A CD1 1 ATOM 2642 C CD2 . LEU A 1 330 ? 23.379 25.038 -7.906 1.00 36.93 ? 362 LEU A CD2 1 ATOM 2643 N N . LYS A 1 331 ? 27.585 22.506 -9.515 1.00 39.36 ? 363 LYS A N 1 ATOM 2644 C CA . LYS A 1 331 ? 28.941 22.728 -9.995 1.00 41.45 ? 363 LYS A CA 1 ATOM 2645 C C . LYS A 1 331 ? 29.043 22.239 -11.429 1.00 38.33 ? 363 LYS A C 1 ATOM 2646 O O . LYS A 1 331 ? 29.866 22.703 -12.215 1.00 37.00 ? 363 LYS A O 1 ATOM 2647 C CB . LYS A 1 331 ? 29.956 22.022 -9.075 1.00 43.81 ? 363 LYS A CB 1 ATOM 2648 C CG . LYS A 1 331 ? 30.024 22.677 -7.701 1.00 46.38 ? 363 LYS A CG 1 ATOM 2649 C CD . LYS A 1 331 ? 30.542 21.749 -6.616 1.00 51.32 ? 363 LYS A CD 1 ATOM 2650 C CE . LYS A 1 331 ? 32.060 21.738 -6.525 1.00 55.82 ? 363 LYS A CE 1 ATOM 2651 N NZ . LYS A 1 331 ? 32.501 21.401 -5.139 1.00 58.76 1 363 LYS A NZ 1 ATOM 2652 N N . GLY A 1 332 ? 28.178 21.305 -11.771 1.00 35.75 ? 364 GLY A N 1 ATOM 2653 C CA . GLY A 1 332 ? 28.324 20.613 -13.013 1.00 35.75 ? 364 GLY A CA 1 ATOM 2654 C C . GLY A 1 332 ? 29.665 19.925 -12.992 1.00 36.58 ? 364 GLY A C 1 ATOM 2655 O O . GLY A 1 332 ? 30.435 20.080 -13.919 1.00 38.02 ? 364 GLY A O 1 ATOM 2656 N N . GLU A 1 333 ? 29.946 19.188 -11.915 1.00 39.00 ? 365 GLU A N 1 ATOM 2657 C CA . GLU A 1 333 ? 31.036 18.214 -11.884 1.00 39.73 ? 365 GLU A CA 1 ATOM 2658 C C . GLU A 1 333 ? 30.669 16.946 -11.088 1.00 35.69 ? 365 GLU A C 1 ATOM 2659 O O . GLU A 1 333 ? 29.899 17.013 -10.142 1.00 32.21 ? 365 GLU A O 1 ATOM 2660 C CB . GLU A 1 333 ? 32.273 18.861 -11.270 1.00 45.94 ? 365 GLU A CB 1 ATOM 2661 C CG . GLU A 1 333 ? 32.894 20.012 -12.068 1.00 51.32 ? 365 GLU A CG 1 ATOM 2662 C CD . GLU A 1 333 ? 33.549 19.604 -13.401 1.00 55.51 ? 365 GLU A CD 1 ATOM 2663 O OE1 . GLU A 1 333 ? 33.703 18.384 -13.692 1.00 55.17 ? 365 GLU A OE1 1 ATOM 2664 O OE2 . GLU A 1 333 ? 33.929 20.537 -14.161 1.00 60.98 -1 365 GLU A OE2 1 ATOM 2665 N N . SER A 1 334 ? 31.250 15.806 -11.469 1.00 34.91 ? 366 SER A N 1 ATOM 2666 C CA . SER A 1 334 ? 31.091 14.524 -10.745 1.00 34.20 ? 366 SER A CA 1 ATOM 2667 C C . SER A 1 334 ? 31.958 14.374 -9.520 1.00 33.25 ? 366 SER A C 1 ATOM 2668 O O . SER A 1 334 ? 32.932 13.619 -9.543 1.00 35.59 ? 366 SER A O 1 ATOM 2669 C CB . SER A 1 334 ? 31.482 13.355 -11.633 1.00 34.85 ? 366 SER A CB 1 ATOM 2670 O OG . SER A 1 334 ? 30.588 13.259 -12.697 1.00 39.09 ? 366 SER A OG 1 ATOM 2671 N N A ILE A 1 335 ? 31.628 15.072 -8.442 0.50 32.22 ? 367 ILE A N 1 ATOM 2672 N N B ILE A 1 335 ? 31.581 15.060 -8.453 0.50 31.89 ? 367 ILE A N 1 ATOM 2673 C CA A ILE A 1 335 ? 32.389 14.928 -7.208 0.50 32.43 ? 367 ILE A CA 1 ATOM 2674 C CA B ILE A 1 335 ? 32.267 14.970 -7.181 0.50 31.78 ? 367 ILE A CA 1 ATOM 2675 C C A ILE A 1 335 ? 31.907 13.715 -6.412 0.50 30.97 ? 367 ILE A C 1 ATOM 2676 C C B ILE A 1 335 ? 31.864 13.703 -6.407 0.50 30.58 ? 367 ILE A C 1 ATOM 2677 O O A ILE A 1 335 ? 31.130 13.838 -5.463 0.50 31.34 ? 367 ILE A O 1 ATOM 2678 O O B ILE A 1 335 ? 31.091 13.781 -5.450 0.50 30.86 ? 367 ILE A O 1 ATOM 2679 C CB A ILE A 1 335 ? 32.281 16.191 -6.347 0.50 33.96 ? 367 ILE A CB 1 ATOM 2680 C CB B ILE A 1 335 ? 31.909 16.208 -6.341 0.50 32.74 ? 367 ILE A CB 1 ATOM 2681 C CG1 A ILE A 1 335 ? 32.293 17.422 -7.253 0.50 34.85 ? 367 ILE A CG1 1 ATOM 2682 C CG1 B ILE A 1 335 ? 30.385 16.379 -6.285 0.50 31.63 ? 367 ILE A CG1 1 ATOM 2683 C CG2 A ILE A 1 335 ? 33.419 16.239 -5.335 0.50 33.35 ? 367 ILE A CG2 1 ATOM 2684 C CG2 B ILE A 1 335 ? 32.537 17.459 -6.941 0.50 33.76 ? 367 ILE A CG2 1 ATOM 2685 C CD1 A ILE A 1 335 ? 33.478 17.444 -8.195 0.50 34.62 ? 367 ILE A CD1 1 ATOM 2686 C CD1 B ILE A 1 335 ? 29.915 17.783 -6.575 0.50 30.87 ? 367 ILE A CD1 1 ATOM 2687 N N . TRP A 1 336 ? 32.366 12.540 -6.816 1.00 29.42 ? 368 TRP A N 1 ATOM 2688 C CA . TRP A 1 336 ? 32.062 11.310 -6.099 1.00 29.39 ? 368 TRP A CA 1 ATOM 2689 C C . TRP A 1 336 ? 32.871 11.315 -4.813 1.00 30.06 ? 368 TRP A C 1 ATOM 2690 O O . TRP A 1 336 ? 34.081 11.159 -4.849 1.00 31.72 ? 368 TRP A O 1 ATOM 2691 C CB . TRP A 1 336 ? 32.382 10.047 -6.921 1.00 29.16 ? 368 TRP A CB 1 ATOM 2692 C CG . TRP A 1 336 ? 31.271 9.623 -7.833 1.00 29.03 ? 368 TRP A CG 1 ATOM 2693 C CD1 . TRP A 1 336 ? 31.119 9.945 -9.161 1.00 29.95 ? 368 TRP A CD1 1 ATOM 2694 C CD2 . TRP A 1 336 ? 30.148 8.812 -7.489 1.00 28.41 ? 368 TRP A CD2 1 ATOM 2695 N NE1 . TRP A 1 336 ? 29.968 9.375 -9.660 1.00 29.34 ? 368 TRP A NE1 1 ATOM 2696 C CE2 . TRP A 1 336 ? 29.346 8.688 -8.652 1.00 28.26 ? 368 TRP A CE2 1 ATOM 2697 C CE3 . TRP A 1 336 ? 29.730 8.190 -6.309 1.00 27.97 ? 368 TRP A CE3 1 ATOM 2698 C CZ2 . TRP A 1 336 ? 28.169 7.963 -8.669 1.00 26.77 ? 368 TRP A CZ2 1 ATOM 2699 C CZ3 . TRP A 1 336 ? 28.554 7.475 -6.327 1.00 27.78 ? 368 TRP A CZ3 1 ATOM 2700 C CH2 . TRP A 1 336 ? 27.787 7.366 -7.506 1.00 27.78 ? 368 TRP A CH2 1 ATOM 2701 N N . LYS A 1 337 ? 32.194 11.520 -3.687 1.00 30.55 ? 369 LYS A N 1 ATOM 2702 C CA . LYS A 1 337 ? 32.822 11.512 -2.375 1.00 29.86 ? 369 LYS A CA 1 ATOM 2703 C C . LYS A 1 337 ? 32.640 10.153 -1.685 1.00 28.65 ? 369 LYS A C 1 ATOM 2704 O O . LYS A 1 337 ? 31.973 9.249 -2.185 1.00 28.59 ? 369 LYS A O 1 ATOM 2705 C CB . LYS A 1 337 ? 32.227 12.601 -1.471 1.00 31.81 ? 369 LYS A CB 1 ATOM 2706 C CG . LYS A 1 337 ? 32.180 14.020 -2.020 1.00 34.11 ? 369 LYS A CG 1 ATOM 2707 C CD . LYS A 1 337 ? 31.409 14.919 -1.047 1.00 38.43 ? 369 LYS A CD 1 ATOM 2708 C CE . LYS A 1 337 ? 30.800 16.156 -1.714 1.00 43.38 ? 369 LYS A CE 1 ATOM 2709 N NZ . LYS A 1 337 ? 29.475 16.554 -1.118 1.00 45.25 1 369 LYS A NZ 1 ATOM 2710 N N . LEU A 1 338 ? 33.277 10.040 -0.527 1.00 27.21 ? 370 LEU A N 1 ATOM 2711 C CA . LEU A 1 338 ? 33.110 8.933 0.386 1.00 24.96 ? 370 LEU A CA 1 ATOM 2712 C C . LEU A 1 338 ? 32.068 9.354 1.390 1.00 22.21 ? 370 LEU A C 1 ATOM 2713 O O . LEU A 1 338 ? 32.188 10.419 1.975 1.00 21.41 ? 370 LEU A O 1 ATOM 2714 C CB . LEU A 1 338 ? 34.412 8.722 1.126 1.00 26.38 ? 370 LEU A CB 1 ATOM 2715 C CG . LEU A 1 338 ? 34.403 7.716 2.269 1.00 28.28 ? 370 LEU A CG 1 ATOM 2716 C CD1 . LEU A 1 338 ? 34.183 6.295 1.773 1.00 28.46 ? 370 LEU A CD1 1 ATOM 2717 C CD2 . LEU A 1 338 ? 35.722 7.831 3.021 1.00 28.76 ? 370 LEU A CD2 1 ATOM 2718 N N . GLU A 1 339 ? 31.064 8.516 1.604 1.00 19.67 ? 371 GLU A N 1 ATOM 2719 C CA . GLU A 1 339 ? 30.035 8.791 2.584 1.00 17.73 ? 371 GLU A CA 1 ATOM 2720 C C . GLU A 1 339 ? 30.491 8.366 3.952 1.00 16.34 ? 371 GLU A C 1 ATOM 2721 O O . GLU A 1 339 ? 30.364 9.126 4.925 1.00 15.93 ? 371 GLU A O 1 ATOM 2722 C CB . GLU A 1 339 ? 28.772 8.020 2.248 1.00 18.10 ? 371 GLU A CB 1 ATOM 2723 C CG . GLU A 1 339 ? 27.524 8.567 2.923 1.00 18.80 ? 371 GLU A CG 1 ATOM 2724 C CD . GLU A 1 339 ? 26.301 7.680 2.704 1.00 19.77 ? 371 GLU A CD 1 ATOM 2725 O OE1 . GLU A 1 339 ? 26.474 6.493 2.359 1.00 19.94 ? 371 GLU A OE1 1 ATOM 2726 O OE2 . GLU A 1 339 ? 25.159 8.162 2.886 1.00 20.51 -1 371 GLU A OE2 1 ATOM 2727 N N . TYR A 1 340 ? 30.987 7.132 4.033 1.00 15.16 ? 372 TYR A N 1 ATOM 2728 C CA . TYR A 1 340 ? 31.339 6.526 5.315 1.00 14.71 ? 372 TYR A CA 1 ATOM 2729 C C . TYR A 1 340 ? 32.062 5.198 5.175 1.00 14.92 ? 372 TYR A C 1 ATOM 2730 O O . TYR A 1 340 ? 31.914 4.495 4.188 1.00 14.23 ? 372 TYR A O 1 ATOM 2731 C CB . TYR A 1 340 ? 30.109 6.323 6.224 1.00 14.05 ? 372 TYR A CB 1 ATOM 2732 C CG . TYR A 1 340 ? 29.256 5.135 5.865 1.00 13.70 ? 372 TYR A CG 1 ATOM 2733 C CD1 . TYR A 1 340 ? 29.558 3.869 6.332 1.00 13.59 ? 372 TYR A CD1 1 ATOM 2734 C CD2 . TYR A 1 340 ? 28.123 5.284 5.081 1.00 13.65 ? 372 TYR A CD2 1 ATOM 2735 C CE1 . TYR A 1 340 ? 28.767 2.775 6.015 1.00 13.50 ? 372 TYR A CE1 1 ATOM 2736 C CE2 . TYR A 1 340 ? 27.320 4.204 4.763 1.00 13.59 ? 372 TYR A CE2 1 ATOM 2737 C CZ . TYR A 1 340 ? 27.650 2.950 5.222 1.00 13.53 ? 372 TYR A CZ 1 ATOM 2738 O OH . TYR A 1 340 ? 26.862 1.870 4.874 1.00 13.62 ? 372 TYR A OH 1 ATOM 2739 N N . ILE A 1 341 ? 32.831 4.878 6.214 1.00 15.93 ? 373 ILE A N 1 ATOM 2740 C CA . ILE A 1 341 ? 33.483 3.585 6.365 1.00 17.01 ? 373 ILE A CA 1 ATOM 2741 C C . ILE A 1 341 ? 32.822 2.823 7.501 1.00 16.88 ? 373 ILE A C 1 ATOM 2742 O O . ILE A 1 341 ? 32.789 3.315 8.630 1.00 17.69 ? 373 ILE A O 1 ATOM 2743 C CB . ILE A 1 341 ? 34.968 3.747 6.708 1.00 17.68 ? 373 ILE A CB 1 ATOM 2744 C CG1 . ILE A 1 341 ? 35.654 4.557 5.611 1.00 18.09 ? 373 ILE A CG1 1 ATOM 2745 C CG2 . ILE A 1 341 ? 35.622 2.367 6.897 1.00 17.90 ? 373 ILE A CG2 1 ATOM 2746 C CD1 . ILE A 1 341 ? 37.035 5.023 6.003 1.00 18.70 ? 373 ILE A CD1 1 ATOM 2747 N N . LEU A 1 342 ? 32.322 1.623 7.223 1.00 16.13 ? 374 LEU A N 1 ATOM 2748 C CA . LEU A 1 342 ? 31.317 1.058 8.097 1.00 15.79 ? 374 LEU A CA 1 ATOM 2749 C C . LEU A 1 342 ? 31.821 0.886 9.529 1.00 16.29 ? 374 LEU A C 1 ATOM 2750 O O . LEU A 1 342 ? 31.174 1.366 10.473 1.00 16.99 ? 374 LEU A O 1 ATOM 2751 C CB . LEU A 1 342 ? 30.760 -0.232 7.536 1.00 15.41 ? 374 LEU A CB 1 ATOM 2752 C CG . LEU A 1 342 ? 29.438 -0.666 8.148 1.00 15.26 ? 374 LEU A CG 1 ATOM 2753 C CD1 . LEU A 1 342 ? 28.746 -1.621 7.203 1.00 15.10 ? 374 LEU A CD1 1 ATOM 2754 C CD2 . LEU A 1 342 ? 29.641 -1.336 9.503 1.00 15.65 ? 374 LEU A CD2 1 ATOM 2755 N N . THR A 1 343 ? 32.976 0.262 9.712 1.00 16.35 ? 375 THR A N 1 ATOM 2756 C CA . THR A 1 343 ? 33.443 0.004 11.072 1.00 16.64 ? 375 THR A CA 1 ATOM 2757 C C . THR A 1 343 ? 33.833 1.291 11.775 1.00 18.57 ? 375 THR A C 1 ATOM 2758 O O . THR A 1 343 ? 33.735 1.375 12.990 1.00 18.56 ? 375 THR A O 1 ATOM 2759 C CB . THR A 1 343 ? 34.637 -0.937 11.127 1.00 15.83 ? 375 THR A CB 1 ATOM 2760 O OG1 . THR A 1 343 ? 35.749 -0.334 10.478 1.00 15.64 ? 375 THR A OG1 1 ATOM 2761 C CG2 . THR A 1 343 ? 34.321 -2.262 10.494 1.00 15.61 ? 375 THR A CG2 1 ATOM 2762 N N . GLN A 1 344 ? 34.260 2.292 11.012 1.00 21.36 ? 376 GLN A N 1 ATOM 2763 C CA . GLN A 1 344 ? 34.570 3.595 11.567 1.00 24.07 ? 376 GLN A CA 1 ATOM 2764 C C . GLN A 1 344 ? 33.385 4.314 12.132 1.00 21.59 ? 376 GLN A C 1 ATOM 2765 O O . GLN A 1 344 ? 33.464 4.779 13.254 1.00 22.11 ? 376 GLN A O 1 ATOM 2766 C CB . GLN A 1 344 ? 35.159 4.507 10.517 1.00 30.53 ? 376 GLN A CB 1 ATOM 2767 C CG . GLN A 1 344 ? 36.624 4.270 10.236 1.00 37.81 ? 376 GLN A CG 1 ATOM 2768 C CD . GLN A 1 344 ? 37.502 4.869 11.315 1.00 48.32 ? 376 GLN A CD 1 ATOM 2769 O OE1 . GLN A 1 344 ? 37.010 5.580 12.210 1.00 56.84 ? 376 GLN A OE1 1 ATOM 2770 N NE2 . GLN A 1 344 ? 38.816 4.587 11.247 1.00 55.05 ? 376 GLN A NE2 1 ATOM 2771 N N . THR A 1 345 ? 32.301 4.459 11.372 1.00 20.08 ? 377 THR A N 1 ATOM 2772 C CA . THR A 1 345 ? 31.209 5.340 11.837 1.00 19.25 ? 377 THR A CA 1 ATOM 2773 C C . THR A 1 345 ? 30.423 4.719 12.920 1.00 19.78 ? 377 THR A C 1 ATOM 2774 O O . THR A 1 345 ? 29.827 5.430 13.713 1.00 19.79 ? 377 THR A O 1 ATOM 2775 C CB . THR A 1 345 ? 30.172 5.719 10.784 1.00 18.15 ? 377 THR A CB 1 ATOM 2776 O OG1 . THR A 1 345 ? 30.011 4.640 9.865 1.00 17.11 ? 377 THR A OG1 1 ATOM 2777 C CG2 . THR A 1 345 ? 30.593 6.962 10.089 1.00 18.44 ? 377 THR A CG2 1 ATOM 2778 N N . TYR A 1 346 ? 30.384 3.397 12.938 1.00 20.51 ? 378 TYR A N 1 ATOM 2779 C CA . TYR A 1 346 ? 29.619 2.702 13.946 1.00 21.58 ? 378 TYR A CA 1 ATOM 2780 C C . TYR A 1 346 ? 30.468 2.190 15.079 1.00 22.53 ? 378 TYR A C 1 ATOM 2781 O O . TYR A 1 346 ? 29.957 1.695 16.097 1.00 22.02 ? 378 TYR A O 1 ATOM 2782 C CB . TYR A 1 346 ? 28.891 1.562 13.296 1.00 21.89 ? 378 TYR A CB 1 ATOM 2783 C CG . TYR A 1 346 ? 27.831 2.033 12.360 1.00 21.96 ? 378 TYR A CG 1 ATOM 2784 C CD1 . TYR A 1 346 ? 26.770 2.790 12.820 1.00 22.27 ? 378 TYR A CD1 1 ATOM 2785 C CD2 . TYR A 1 346 ? 27.876 1.703 11.010 1.00 22.25 ? 378 TYR A CD2 1 ATOM 2786 C CE1 . TYR A 1 346 ? 25.775 3.216 11.950 1.00 23.76 ? 378 TYR A CE1 1 ATOM 2787 C CE2 . TYR A 1 346 ? 26.887 2.116 10.132 1.00 22.57 ? 378 TYR A CE2 1 ATOM 2788 C CZ . TYR A 1 346 ? 25.836 2.877 10.598 1.00 23.05 ? 378 TYR A CZ 1 ATOM 2789 O OH . TYR A 1 346 ? 24.843 3.287 9.738 1.00 22.25 ? 378 TYR A OH 1 ATOM 2790 N N . ASP A 1 347 ? 31.769 2.314 14.896 1.00 24.63 ? 379 ASP A N 1 ATOM 2791 C CA . ASP A 1 347 ? 32.701 1.907 15.905 1.00 28.03 ? 379 ASP A CA 1 ATOM 2792 C C . ASP A 1 347 ? 32.450 0.466 16.286 1.00 27.89 ? 379 ASP A C 1 ATOM 2793 O O . ASP A 1 347 ? 32.084 0.182 17.413 1.00 28.84 ? 379 ASP A O 1 ATOM 2794 C CB . ASP A 1 347 ? 32.583 2.816 17.115 1.00 30.41 ? 379 ASP A CB 1 ATOM 2795 C CG . ASP A 1 347 ? 33.895 3.008 17.798 1.00 34.14 ? 379 ASP A CG 1 ATOM 2796 O OD1 . ASP A 1 347 ? 34.347 2.018 18.426 1.00 37.47 ? 379 ASP A OD1 1 ATOM 2797 O OD2 . ASP A 1 347 ? 34.474 4.130 17.678 1.00 36.90 -1 379 ASP A OD2 1 ATOM 2798 N N . ILE A 1 348 ? 32.610 -0.421 15.309 1.00 27.27 ? 380 ILE A N 1 ATOM 2799 C CA . ILE A 1 348 ? 32.525 -1.837 15.531 1.00 27.83 ? 380 ILE A CA 1 ATOM 2800 C C . ILE A 1 348 ? 33.739 -2.489 14.885 1.00 29.11 ? 380 ILE A C 1 ATOM 2801 O O . ILE A 1 348 ? 34.423 -1.872 14.101 1.00 27.21 ? 380 ILE A O 1 ATOM 2802 C CB . ILE A 1 348 ? 31.207 -2.415 15.000 1.00 28.67 ? 380 ILE A CB 1 ATOM 2803 C CG1 . ILE A 1 348 ? 31.036 -2.112 13.519 1.00 30.75 ? 380 ILE A CG1 1 ATOM 2804 C CG2 . ILE A 1 348 ? 30.027 -1.818 15.750 1.00 28.82 ? 380 ILE A CG2 1 ATOM 2805 C CD1 . ILE A 1 348 ? 29.899 -2.886 12.878 1.00 31.56 ? 380 ILE A CD1 1 ATOM 2806 N N . GLU A 1 349 ? 33.998 -3.736 15.251 1.00 33.25 ? 381 GLU A N 1 ATOM 2807 C CA . GLU A 1 349 ? 35.211 -4.452 14.874 1.00 35.88 ? 381 GLU A CA 1 ATOM 2808 C C . GLU A 1 349 ? 35.330 -4.770 13.393 1.00 33.47 ? 381 GLU A C 1 ATOM 2809 O O . GLU A 1 349 ? 36.346 -4.487 12.785 1.00 33.42 ? 381 GLU A O 1 ATOM 2810 C CB . GLU A 1 349 ? 35.269 -5.774 15.645 1.00 42.69 ? 381 GLU A CB 1 ATOM 2811 C CG . GLU A 1 349 ? 35.810 -5.648 17.055 1.00 50.08 ? 381 GLU A CG 1 ATOM 2812 C CD . GLU A 1 349 ? 37.264 -5.196 17.056 1.00 59.25 ? 381 GLU A CD 1 ATOM 2813 O OE1 . GLU A 1 349 ? 38.130 -5.954 16.542 1.00 64.27 ? 381 GLU A OE1 1 ATOM 2814 O OE2 . GLU A 1 349 ? 37.536 -4.072 17.551 1.00 64.12 -1 381 GLU A OE2 1 ATOM 2815 N N . ASP A 1 350 ? 34.292 -5.387 12.833 1.00 31.00 ? 382 ASP A N 1 ATOM 2816 C CA . ASP A 1 350 ? 34.331 -5.961 11.491 1.00 29.08 ? 382 ASP A CA 1 ATOM 2817 C C . ASP A 1 350 ? 32.892 -6.128 10.960 1.00 27.84 ? 382 ASP A C 1 ATOM 2818 O O . ASP A 1 350 ? 31.989 -5.441 11.432 1.00 29.93 ? 382 ASP A O 1 ATOM 2819 C CB . ASP A 1 350 ? 35.057 -7.297 11.558 1.00 29.97 ? 382 ASP A CB 1 ATOM 2820 C CG . ASP A 1 350 ? 34.409 -8.258 12.530 1.00 30.92 ? 382 ASP A CG 1 ATOM 2821 O OD1 . ASP A 1 350 ? 33.198 -8.130 12.764 1.00 30.87 ? 382 ASP A OD1 1 ATOM 2822 O OD2 . ASP A 1 350 ? 35.102 -9.144 13.066 1.00 33.24 -1 382 ASP A OD2 1 ATOM 2823 N N . LEU A 1 351 ? 32.658 -7.006 9.987 1.00 24.69 ? 383 LEU A N 1 ATOM 2824 C CA . LEU A 1 351 ? 31.329 -7.153 9.425 1.00 22.83 ? 383 LEU A CA 1 ATOM 2825 C C . LEU A 1 351 ? 30.807 -8.534 9.715 1.00 23.39 ? 383 LEU A C 1 ATOM 2826 O O . LEU A 1 351 ? 29.958 -9.066 9.008 1.00 23.13 ? 383 LEU A O 1 ATOM 2827 C CB . LEU A 1 351 ? 31.360 -6.849 7.925 1.00 22.10 ? 383 LEU A CB 1 ATOM 2828 C CG . LEU A 1 351 ? 31.012 -5.417 7.474 1.00 21.54 ? 383 LEU A CG 1 ATOM 2829 C CD1 . LEU A 1 351 ? 31.599 -4.349 8.377 1.00 21.35 ? 383 LEU A CD1 1 ATOM 2830 C CD2 . LEU A 1 351 ? 31.454 -5.181 6.043 1.00 21.30 ? 383 LEU A CD2 1 ATOM 2831 N N . GLN A 1 352 ? 31.312 -9.123 10.785 1.00 25.27 ? 384 GLN A N 1 ATOM 2832 C CA . GLN A 1 352 ? 30.864 -10.444 11.210 1.00 26.64 ? 384 GLN A CA 1 ATOM 2833 C C . GLN A 1 352 ? 29.431 -10.334 11.658 1.00 25.53 ? 384 GLN A C 1 ATOM 2834 O O . GLN A 1 352 ? 28.977 -9.244 11.950 1.00 26.77 ? 384 GLN A O 1 ATOM 2835 C CB . GLN A 1 352 ? 31.705 -10.932 12.383 1.00 28.97 ? 384 GLN A CB 1 ATOM 2836 C CG . GLN A 1 352 ? 33.081 -11.428 11.986 1.00 30.18 ? 384 GLN A CG 1 ATOM 2837 C CD . GLN A 1 352 ? 33.017 -12.835 11.432 1.00 31.37 ? 384 GLN A CD 1 ATOM 2838 O OE1 . GLN A 1 352 ? 33.392 -13.064 10.288 1.00 32.91 ? 384 GLN A OE1 1 ATOM 2839 N NE2 . GLN A 1 352 ? 32.502 -13.781 12.229 1.00 31.25 ? 384 GLN A NE2 1 ATOM 2840 N N . PRO A 1 353 ? 28.712 -11.450 11.728 1.00 24.68 ? 385 PRO A N 1 ATOM 2841 C CA . PRO A 1 353 ? 27.301 -11.341 12.119 1.00 25.10 ? 385 PRO A CA 1 ATOM 2842 C C . PRO A 1 353 ? 27.072 -10.850 13.548 1.00 25.75 ? 385 PRO A C 1 ATOM 2843 O O . PRO A 1 353 ? 26.137 -10.089 13.787 1.00 25.74 ? 385 PRO A O 1 ATOM 2844 C CB . PRO A 1 353 ? 26.774 -12.767 11.937 1.00 24.73 ? 385 PRO A CB 1 ATOM 2845 C CG . PRO A 1 353 ? 27.667 -13.353 10.894 1.00 24.87 ? 385 PRO A CG 1 ATOM 2846 C CD . PRO A 1 353 ? 29.027 -12.767 11.165 1.00 24.70 ? 385 PRO A CD 1 ATOM 2847 N N . GLU A 1 354 ? 27.929 -11.272 14.468 1.00 26.49 ? 386 GLU A N 1 ATOM 2848 C CA . GLU A 1 354 ? 27.829 -10.875 15.859 1.00 27.88 ? 386 GLU A CA 1 ATOM 2849 C C . GLU A 1 354 ? 28.104 -9.363 15.916 1.00 25.53 ? 386 GLU A C 1 ATOM 2850 O O . GLU A 1 354 ? 27.356 -8.602 16.549 1.00 25.40 ? 386 GLU A O 1 ATOM 2851 C CB . GLU A 1 354 ? 28.819 -11.654 16.753 1.00 33.52 ? 386 GLU A CB 1 ATOM 2852 C CG . GLU A 1 354 ? 29.106 -13.127 16.364 1.00 40.54 ? 386 GLU A CG 1 ATOM 2853 C CD . GLU A 1 354 ? 30.232 -13.317 15.281 1.00 46.89 ? 386 GLU A CD 1 ATOM 2854 O OE1 . GLU A 1 354 ? 31.429 -12.939 15.539 1.00 50.69 ? 386 GLU A OE1 1 ATOM 2855 O OE2 . GLU A 1 354 ? 29.921 -13.857 14.170 1.00 42.15 -1 386 GLU A OE2 1 ATOM 2856 N N . SER A 1 355 ? 29.147 -8.908 15.221 1.00 22.95 ? 387 SER A N 1 ATOM 2857 C CA . SER A 1 355 ? 29.436 -7.456 15.142 1.00 21.15 ? 387 SER A CA 1 ATOM 2858 C C . SER A 1 355 ? 28.230 -6.604 14.773 1.00 19.69 ? 387 SER A C 1 ATOM 2859 O O . SER A 1 355 ? 27.996 -5.578 15.378 1.00 20.97 ? 387 SER A O 1 ATOM 2860 C CB . SER A 1 355 ? 30.539 -7.157 14.134 1.00 20.53 ? 387 SER A CB 1 ATOM 2861 O OG . SER A 1 355 ? 31.795 -7.465 14.676 1.00 20.55 ? 387 SER A OG 1 ATOM 2862 N N . LEU A 1 356 ? 27.491 -7.027 13.763 1.00 17.99 ? 388 LEU A N 1 ATOM 2863 C CA . LEU A 1 356 ? 26.375 -6.258 13.246 1.00 17.29 ? 388 LEU A CA 1 ATOM 2864 C C . LEU A 1 356 ? 25.121 -6.419 14.087 1.00 17.65 ? 388 LEU A C 1 ATOM 2865 O O . LEU A 1 356 ? 24.334 -5.469 14.225 1.00 17.82 ? 388 LEU A O 1 ATOM 2866 C CB . LEU A 1 356 ? 26.069 -6.679 11.805 1.00 16.50 ? 388 LEU A CB 1 ATOM 2867 C CG . LEU A 1 356 ? 27.151 -6.320 10.815 1.00 15.76 ? 388 LEU A CG 1 ATOM 2868 C CD1 . LEU A 1 356 ? 26.777 -6.817 9.442 1.00 15.71 ? 388 LEU A CD1 1 ATOM 2869 C CD2 . LEU A 1 356 ? 27.337 -4.820 10.792 1.00 15.82 ? 388 LEU A CD2 1 ATOM 2870 N N . TYR A 1 357 ? 24.903 -7.625 14.603 1.00 17.55 ? 389 TYR A N 1 ATOM 2871 C CA . TYR A 1 357 ? 23.809 -7.844 15.519 1.00 17.95 ? 389 TYR A CA 1 ATOM 2872 C C . TYR A 1 357 ? 23.945 -6.910 16.709 1.00 17.23 ? 389 TYR A C 1 ATOM 2873 O O . TYR A 1 357 ? 22.959 -6.332 17.193 1.00 16.76 ? 389 TYR A O 1 ATOM 2874 C CB . TYR A 1 357 ? 23.823 -9.253 16.026 1.00 19.24 ? 389 TYR A CB 1 ATOM 2875 C CG . TYR A 1 357 ? 22.563 -9.635 16.753 1.00 20.80 ? 389 TYR A CG 1 ATOM 2876 C CD1 . TYR A 1 357 ? 21.345 -9.737 16.061 1.00 21.68 ? 389 TYR A CD1 1 ATOM 2877 C CD2 . TYR A 1 357 ? 22.587 -9.930 18.110 1.00 21.22 ? 389 TYR A CD2 1 ATOM 2878 C CE1 . TYR A 1 357 ? 20.187 -10.106 16.702 1.00 22.47 ? 389 TYR A CE1 1 ATOM 2879 C CE2 . TYR A 1 357 ? 21.436 -10.311 18.761 1.00 22.51 ? 389 TYR A CE2 1 ATOM 2880 C CZ . TYR A 1 357 ? 20.247 -10.395 18.046 1.00 23.66 ? 389 TYR A CZ 1 ATOM 2881 O OH . TYR A 1 357 ? 19.105 -10.762 18.704 1.00 27.92 ? 389 TYR A OH 1 ATOM 2882 N N . GLY A 1 358 ? 25.180 -6.747 17.169 1.00 16.01 ? 390 GLY A N 1 ATOM 2883 C CA . GLY A 1 358 ? 25.444 -5.824 18.262 1.00 15.61 ? 390 GLY A CA 1 ATOM 2884 C C . GLY A 1 358 ? 25.132 -4.375 17.965 1.00 14.99 ? 390 GLY A C 1 ATOM 2885 O O . GLY A 1 358 ? 24.678 -3.640 18.848 1.00 15.10 ? 390 GLY A O 1 ATOM 2886 N N . LEU A 1 359 ? 25.413 -3.956 16.733 1.00 14.29 ? 391 LEU A N 1 ATOM 2887 C CA . LEU A 1 359 ? 25.087 -2.615 16.294 1.00 13.84 ? 391 LEU A CA 1 ATOM 2888 C C . LEU A 1 359 ? 23.573 -2.478 16.262 1.00 14.08 ? 391 LEU A C 1 ATOM 2889 O O . LEU A 1 359 ? 23.015 -1.467 16.670 1.00 13.76 ? 391 LEU A O 1 ATOM 2890 C CB . LEU A 1 359 ? 25.701 -2.344 14.926 1.00 13.40 ? 391 LEU A CB 1 ATOM 2891 C CG . LEU A 1 359 ? 25.510 -0.962 14.302 1.00 13.11 ? 391 LEU A CG 1 ATOM 2892 C CD1 . LEU A 1 359 ? 26.012 0.150 15.183 1.00 13.01 ? 391 LEU A CD1 1 ATOM 2893 C CD2 . LEU A 1 359 ? 26.244 -0.892 12.978 1.00 13.14 ? 391 LEU A CD2 1 ATOM 2894 N N . ALA A 1 360 ? 22.900 -3.522 15.807 1.00 14.67 ? 392 ALA A N 1 ATOM 2895 C CA . ALA A 1 360 ? 21.455 -3.477 15.721 1.00 15.33 ? 392 ALA A CA 1 ATOM 2896 C C . ALA A 1 360 ? 20.846 -3.207 17.091 1.00 16.23 ? 392 ALA A C 1 ATOM 2897 O O . ALA A 1 360 ? 19.936 -2.393 17.223 1.00 16.03 ? 392 ALA A O 1 ATOM 2898 C CB . ALA A 1 360 ? 20.918 -4.764 15.128 1.00 15.09 ? 392 ALA A CB 1 ATOM 2899 N N . LYS A 1 361 ? 21.376 -3.868 18.113 1.00 17.49 ? 393 LYS A N 1 ATOM 2900 C CA . LYS A 1 361 ? 20.877 -3.698 19.465 1.00 18.02 ? 393 LYS A CA 1 ATOM 2901 C C . LYS A 1 361 ? 21.081 -2.277 19.888 1.00 18.32 ? 393 LYS A C 1 ATOM 2902 O O . LYS A 1 361 ? 20.179 -1.666 20.430 1.00 18.51 ? 393 LYS A O 1 ATOM 2903 C CB . LYS A 1 361 ? 21.611 -4.616 20.409 1.00 19.11 ? 393 LYS A CB 1 ATOM 2904 C CG . LYS A 1 361 ? 21.269 -6.094 20.247 1.00 20.57 ? 393 LYS A CG 1 ATOM 2905 C CD . LYS A 1 361 ? 19.905 -6.409 20.846 1.00 22.35 ? 393 LYS A CD 1 ATOM 2906 C CE . LYS A 1 361 ? 19.703 -7.902 21.081 1.00 24.44 ? 393 LYS A CE 1 ATOM 2907 N NZ . LYS A 1 361 ? 18.393 -8.205 21.741 1.00 25.52 1 393 LYS A NZ 1 ATOM 2908 N N . GLN A 1 362 ? 22.250 -1.724 19.595 1.00 19.47 ? 394 GLN A N 1 ATOM 2909 C CA . GLN A 1 362 ? 22.521 -0.326 19.930 1.00 20.97 ? 394 GLN A CA 1 ATOM 2910 C C . GLN A 1 362 ? 21.487 0.606 19.307 1.00 19.76 ? 394 GLN A C 1 ATOM 2911 O O . GLN A 1 362 ? 21.165 1.628 19.859 1.00 18.96 ? 394 GLN A O 1 ATOM 2912 C CB . GLN A 1 362 ? 23.906 0.111 19.444 1.00 24.02 ? 394 GLN A CB 1 ATOM 2913 C CG . GLN A 1 362 ? 25.141 -0.529 20.085 1.00 26.09 ? 394 GLN A CG 1 ATOM 2914 C CD . GLN A 1 362 ? 26.419 0.204 19.629 1.00 30.32 ? 394 GLN A CD 1 ATOM 2915 O OE1 . GLN A 1 362 ? 27.327 -0.368 18.984 1.00 30.29 ? 394 GLN A OE1 1 ATOM 2916 N NE2 . GLN A 1 362 ? 26.476 1.509 19.939 1.00 34.15 ? 394 GLN A NE2 1 ATOM 2917 N N . PHE A 1 363 ? 20.991 0.265 18.131 1.00 20.01 ? 395 PHE A N 1 ATOM 2918 C CA . PHE A 1 363 ? 19.965 1.063 17.494 1.00 20.07 ? 395 PHE A CA 1 ATOM 2919 C C . PHE A 1 363 ? 18.697 1.155 18.312 1.00 21.17 ? 395 PHE A C 1 ATOM 2920 O O . PHE A 1 363 ? 18.010 2.168 18.251 1.00 22.13 ? 395 PHE A O 1 ATOM 2921 C CB . PHE A 1 363 ? 19.585 0.478 16.141 1.00 19.66 ? 395 PHE A CB 1 ATOM 2922 C CG . PHE A 1 363 ? 20.638 0.594 15.100 1.00 19.50 ? 395 PHE A CG 1 ATOM 2923 C CD1 . PHE A 1 363 ? 21.788 1.365 15.288 1.00 19.78 ? 395 PHE A CD1 1 ATOM 2924 C CD2 . PHE A 1 363 ? 20.449 -0.026 13.889 1.00 19.63 ? 395 PHE A CD2 1 ATOM 2925 C CE1 . PHE A 1 363 ? 22.740 1.474 14.290 1.00 19.67 ? 395 PHE A CE1 1 ATOM 2926 C CE2 . PHE A 1 363 ? 21.397 0.080 12.887 1.00 19.88 ? 395 PHE A CE2 1 ATOM 2927 C CZ . PHE A 1 363 ? 22.543 0.833 13.088 1.00 19.69 ? 395 PHE A CZ 1 ATOM 2928 N N . THR A 1 364 ? 18.382 0.094 19.056 1.00 22.02 ? 396 THR A N 1 ATOM 2929 C CA . THR A 1 364 ? 17.133 0.001 19.827 1.00 22.29 ? 396 THR A CA 1 ATOM 2930 C C . THR A 1 364 ? 17.056 0.969 21.042 1.00 22.56 ? 396 THR A C 1 ATOM 2931 O O . THR A 1 364 ? 15.975 1.387 21.461 1.00 24.43 ? 396 THR A O 1 ATOM 2932 C CB . THR A 1 364 ? 16.900 -1.455 20.274 1.00 22.69 ? 396 THR A CB 1 ATOM 2933 O OG1 . THR A 1 364 ? 17.893 -1.844 21.227 1.00 22.33 ? 396 THR A OG1 1 ATOM 2934 C CG2 . THR A 1 364 ? 16.978 -2.395 19.083 1.00 22.92 ? 396 THR A CG2 1 ATOM 2935 N N . ILE A 1 365 ? 18.199 1.334 21.594 1.00 22.05 ? 397 ILE A N 1 ATOM 2936 C CA . ILE A 1 365 ? 18.267 2.399 22.581 1.00 22.12 ? 397 ILE A CA 1 ATOM 2937 C C . ILE A 1 365 ? 17.370 3.580 22.217 1.00 24.74 ? 397 ILE A C 1 ATOM 2938 O O . ILE A 1 365 ? 17.419 4.057 21.085 1.00 23.84 ? 397 ILE A O 1 ATOM 2939 C CB . ILE A 1 365 ? 19.703 2.939 22.656 1.00 20.89 ? 397 ILE A CB 1 ATOM 2940 C CG1 . ILE A 1 365 ? 20.627 1.883 23.255 1.00 20.26 ? 397 ILE A CG1 1 ATOM 2941 C CG2 . ILE A 1 365 ? 19.771 4.235 23.457 1.00 20.83 ? 397 ILE A CG2 1 ATOM 2942 C CD1 . ILE A 1 365 ? 22.091 2.237 23.185 1.00 20.22 ? 397 ILE A CD1 1 ATOM 2943 N N . LEU A 1 366 ? 16.577 4.067 23.178 1.00 28.35 ? 398 LEU A N 1 ATOM 2944 C CA . LEU A 1 366 ? 15.816 5.312 22.983 1.00 31.71 ? 398 LEU A CA 1 ATOM 2945 C C . LEU A 1 366 ? 16.710 6.382 22.377 1.00 31.83 ? 398 LEU A C 1 ATOM 2946 O O . LEU A 1 366 ? 17.783 6.669 22.890 1.00 32.13 ? 398 LEU A O 1 ATOM 2947 C CB . LEU A 1 366 ? 15.279 5.856 24.314 1.00 36.16 ? 398 LEU A CB 1 ATOM 2948 C CG . LEU A 1 366 ? 13.874 5.544 24.884 1.00 39.06 ? 398 LEU A CG 1 ATOM 2949 C CD1 . LEU A 1 366 ? 13.239 4.264 24.322 1.00 40.59 ? 398 LEU A CD1 1 ATOM 2950 C CD2 . LEU A 1 366 ? 13.945 5.504 26.422 1.00 38.42 ? 398 LEU A CD2 1 ATOM 2951 N N . ASP A 1 367 ? 16.260 6.981 21.291 1.00 33.45 ? 399 ASP A N 1 ATOM 2952 C CA . ASP A 1 367 ? 16.989 8.087 20.650 1.00 35.15 ? 399 ASP A CA 1 ATOM 2953 C C . ASP A 1 367 ? 18.421 7.758 20.266 1.00 32.07 ? 399 ASP A C 1 ATOM 2954 O O . ASP A 1 367 ? 19.276 8.638 20.266 1.00 30.63 ? 399 ASP A O 1 ATOM 2955 C CB . ASP A 1 367 ? 16.959 9.347 21.524 1.00 38.64 ? 399 ASP A CB 1 ATOM 2956 C CG . ASP A 1 367 ? 15.542 9.844 21.771 1.00 43.91 ? 399 ASP A CG 1 ATOM 2957 O OD1 . ASP A 1 367 ? 14.811 9.210 22.602 1.00 44.53 ? 399 ASP A OD1 1 ATOM 2958 O OD2 . ASP A 1 367 ? 15.171 10.857 21.110 1.00 44.89 -1 399 ASP A OD2 1 ATOM 2959 N N . SER A 1 368 ? 18.662 6.500 19.896 1.00 29.58 ? 400 SER A N 1 ATOM 2960 C CA . SER A 1 368 ? 19.994 6.057 19.486 1.00 27.49 ? 400 SER A CA 1 ATOM 2961 C C . SER A 1 368 ? 20.581 6.998 18.449 1.00 26.75 ? 400 SER A C 1 ATOM 2962 O O . SER A 1 368 ? 20.051 7.119 17.364 1.00 26.57 ? 400 SER A O 1 ATOM 2963 C CB . SER A 1 368 ? 19.951 4.630 18.917 1.00 25.84 ? 400 SER A CB 1 ATOM 2964 O OG . SER A 1 368 ? 21.250 4.178 18.610 1.00 24.08 ? 400 SER A OG 1 ATOM 2965 N N . LYS A 1 369 ? 21.667 7.668 18.808 1.00 27.20 ? 401 LYS A N 1 ATOM 2966 C CA . LYS A 1 369 ? 22.466 8.428 17.849 1.00 27.73 ? 401 LYS A CA 1 ATOM 2967 C C . LYS A 1 369 ? 22.943 7.504 16.727 1.00 24.36 ? 401 LYS A C 1 ATOM 2968 O O . LYS A 1 369 ? 23.177 7.966 15.625 1.00 24.41 ? 401 LYS A O 1 ATOM 2969 C CB . LYS A 1 369 ? 23.685 9.098 18.542 1.00 32.17 ? 401 LYS A CB 1 ATOM 2970 C CG . LYS A 1 369 ? 23.506 10.537 19.076 1.00 38.03 ? 401 LYS A CG 1 ATOM 2971 C CD . LYS A 1 369 ? 22.376 10.725 20.108 1.00 45.07 ? 401 LYS A CD 1 ATOM 2972 C CE . LYS A 1 369 ? 21.318 11.791 19.671 1.00 50.53 ? 401 LYS A CE 1 ATOM 2973 N NZ . LYS A 1 369 ? 19.884 11.564 20.120 1.00 49.31 1 401 LYS A NZ 1 ATOM 2974 N N . GLN A 1 370 ? 23.096 6.207 17.008 1.00 22.23 ? 402 GLN A N 1 ATOM 2975 C CA . GLN A 1 370 ? 23.592 5.235 16.015 1.00 20.92 ? 402 GLN A CA 1 ATOM 2976 C C . GLN A 1 370 ? 22.584 5.001 14.941 1.00 19.92 ? 402 GLN A C 1 ATOM 2977 O O . GLN A 1 370 ? 22.885 5.151 13.775 1.00 20.44 ? 402 GLN A O 1 ATOM 2978 C CB . GLN A 1 370 ? 23.898 3.875 16.639 1.00 20.99 ? 402 GLN A CB 1 ATOM 2979 C CG . GLN A 1 370 ? 25.128 3.824 17.522 1.00 20.99 ? 402 GLN A CG 1 ATOM 2980 C CD . GLN A 1 370 ? 26.407 4.013 16.734 1.00 20.88 ? 402 GLN A CD 1 ATOM 2981 O OE1 . GLN A 1 370 ? 26.638 5.083 16.114 1.00 21.34 ? 402 GLN A OE1 1 ATOM 2982 N NE2 . GLN A 1 370 ? 27.263 2.981 16.756 1.00 20.20 ? 402 GLN A NE2 1 ATOM 2983 N N . PHE A 1 371 ? 21.382 4.622 15.335 1.00 18.93 ? 403 PHE A N 1 ATOM 2984 C CA . PHE A 1 371 ? 20.288 4.537 14.392 1.00 18.57 ? 403 PHE A CA 1 ATOM 2985 C C . PHE A 1 371 ? 20.099 5.835 13.603 1.00 18.66 ? 403 PHE A C 1 ATOM 2986 O O . PHE A 1 371 ? 19.842 5.777 12.404 1.00 20.06 ? 403 PHE A O 1 ATOM 2987 C CB . PHE A 1 371 ? 18.976 4.186 15.089 1.00 18.50 ? 403 PHE A CB 1 ATOM 2988 C CG . PHE A 1 371 ? 17.815 4.108 14.155 1.00 18.20 ? 403 PHE A CG 1 ATOM 2989 C CD1 . PHE A 1 371 ? 17.585 2.961 13.421 1.00 18.35 ? 403 PHE A CD1 1 ATOM 2990 C CD2 . PHE A 1 371 ? 16.979 5.193 13.976 1.00 17.93 ? 403 PHE A CD2 1 ATOM 2991 C CE1 . PHE A 1 371 ? 16.526 2.902 12.538 1.00 18.35 ? 403 PHE A CE1 1 ATOM 2992 C CE2 . PHE A 1 371 ? 15.911 5.141 13.104 1.00 17.64 ? 403 PHE A CE2 1 ATOM 2993 C CZ . PHE A 1 371 ? 15.686 3.997 12.385 1.00 18.23 ? 403 PHE A CZ 1 ATOM 2994 N N . ILE A 1 372 ? 20.223 6.999 14.233 1.00 18.06 ? 404 ILE A N 1 ATOM 2995 C CA . ILE A 1 372 ? 20.015 8.219 13.462 1.00 18.75 ? 404 ILE A CA 1 ATOM 2996 C C . ILE A 1 372 ? 20.953 8.192 12.276 1.00 18.30 ? 404 ILE A C 1 ATOM 2997 O O . ILE A 1 372 ? 20.517 8.444 11.171 1.00 18.85 ? 404 ILE A O 1 ATOM 2998 C CB . ILE A 1 372 ? 20.258 9.579 14.187 1.00 19.81 ? 404 ILE A CB 1 ATOM 2999 C CG1 . ILE A 1 372 ? 19.669 9.659 15.601 1.00 20.82 ? 404 ILE A CG1 1 ATOM 3000 C CG2 . ILE A 1 372 ? 19.653 10.705 13.362 1.00 19.98 ? 404 ILE A CG2 1 ATOM 3001 C CD1 . ILE A 1 372 ? 18.201 9.292 15.735 1.00 21.34 ? 404 ILE A CD1 1 ATOM 3002 N N . LYS A 1 373 ? 22.235 7.915 12.506 1.00 18.08 ? 405 LYS A N 1 ATOM 3003 C CA . LYS A 1 373 ? 23.191 7.821 11.407 1.00 18.22 ? 405 LYS A CA 1 ATOM 3004 C C . LYS A 1 373 ? 22.643 6.876 10.348 1.00 16.20 ? 405 LYS A C 1 ATOM 3005 O O . LYS A 1 373 ? 22.538 7.224 9.182 1.00 14.78 ? 405 LYS A O 1 ATOM 3006 C CB . LYS A 1 373 ? 24.524 7.233 11.880 1.00 20.51 ? 405 LYS A CB 1 ATOM 3007 C CG . LYS A 1 373 ? 25.609 8.200 12.291 1.00 22.71 ? 405 LYS A CG 1 ATOM 3008 C CD . LYS A 1 373 ? 26.922 7.430 12.471 1.00 25.56 ? 405 LYS A CD 1 ATOM 3009 C CE . LYS A 1 373 ? 27.776 7.926 13.659 1.00 28.60 ? 405 LYS A CE 1 ATOM 3010 N NZ . LYS A 1 373 ? 29.218 8.127 13.262 1.00 29.86 1 405 LYS A NZ 1 ATOM 3011 N N . TYR A 1 374 ? 22.309 5.669 10.783 1.00 14.68 ? 406 TYR A N 1 ATOM 3012 C CA . TYR A 1 374 ? 21.915 4.637 9.876 1.00 14.38 ? 406 TYR A CA 1 ATOM 3013 C C . TYR A 1 374 ? 20.771 5.084 9.007 1.00 15.54 ? 406 TYR A C 1 ATOM 3014 O O . TYR A 1 374 ? 20.664 4.643 7.860 1.00 16.53 ? 406 TYR A O 1 ATOM 3015 C CB . TYR A 1 374 ? 21.527 3.374 10.628 1.00 13.50 ? 406 TYR A CB 1 ATOM 3016 C CG . TYR A 1 374 ? 21.011 2.217 9.779 1.00 12.48 ? 406 TYR A CG 1 ATOM 3017 C CD1 . TYR A 1 374 ? 21.861 1.245 9.275 1.00 12.13 ? 406 TYR A CD1 1 ATOM 3018 C CD2 . TYR A 1 374 ? 19.672 2.089 9.513 1.00 12.23 ? 406 TYR A CD2 1 ATOM 3019 C CE1 . TYR A 1 374 ? 21.372 0.167 8.531 1.00 11.92 ? 406 TYR A CE1 1 ATOM 3020 C CE2 . TYR A 1 374 ? 19.176 1.022 8.769 1.00 12.08 ? 406 TYR A CE2 1 ATOM 3021 C CZ . TYR A 1 374 ? 20.022 0.059 8.286 1.00 11.76 ? 406 TYR A CZ 1 ATOM 3022 O OH . TYR A 1 374 ? 19.481 -0.979 7.568 1.00 11.20 ? 406 TYR A OH 1 ATOM 3023 N N . TYR A 1 375 ? 19.911 5.952 9.518 1.00 16.40 ? 407 TYR A N 1 ATOM 3024 C CA . TYR A 1 375 ? 18.801 6.439 8.707 1.00 17.01 ? 407 TYR A CA 1 ATOM 3025 C C . TYR A 1 375 ? 19.189 7.571 7.721 1.00 19.40 ? 407 TYR A C 1 ATOM 3026 O O . TYR A 1 375 ? 18.604 7.651 6.647 1.00 19.74 ? 407 TYR A O 1 ATOM 3027 C CB . TYR A 1 375 ? 17.653 6.810 9.614 1.00 16.08 ? 407 TYR A CB 1 ATOM 3028 C CG . TYR A 1 375 ? 16.304 6.778 8.967 1.00 15.63 ? 407 TYR A CG 1 ATOM 3029 C CD1 . TYR A 1 375 ? 15.666 5.596 8.674 1.00 15.48 ? 407 TYR A CD1 1 ATOM 3030 C CD2 . TYR A 1 375 ? 15.651 7.940 8.692 1.00 16.02 ? 407 TYR A CD2 1 ATOM 3031 C CE1 . TYR A 1 375 ? 14.424 5.591 8.074 1.00 15.59 ? 407 TYR A CE1 1 ATOM 3032 C CE2 . TYR A 1 375 ? 14.402 7.944 8.118 1.00 16.24 ? 407 TYR A CE2 1 ATOM 3033 C CZ . TYR A 1 375 ? 13.801 6.780 7.804 1.00 15.93 ? 407 TYR A CZ 1 ATOM 3034 O OH . TYR A 1 375 ? 12.564 6.888 7.239 1.00 16.76 ? 407 TYR A OH 1 ATOM 3035 N N . ASN A 1 376 ? 20.169 8.418 8.048 1.00 22.38 ? 408 ASN A N 1 ATOM 3036 C CA . ASN A 1 376 ? 20.768 9.287 7.036 1.00 26.12 ? 408 ASN A CA 1 ATOM 3037 C C . ASN A 1 376 ? 21.377 8.448 5.967 1.00 24.99 ? 408 ASN A C 1 ATOM 3038 O O . ASN A 1 376 ? 21.196 8.717 4.804 1.00 28.06 ? 408 ASN A O 1 ATOM 3039 C CB . ASN A 1 376 ? 21.900 10.155 7.574 1.00 32.38 ? 408 ASN A CB 1 ATOM 3040 C CG . ASN A 1 376 ? 21.404 11.265 8.465 1.00 39.74 ? 408 ASN A CG 1 ATOM 3041 O OD1 . ASN A 1 376 ? 20.476 11.978 8.087 1.00 48.85 ? 408 ASN A OD1 1 ATOM 3042 N ND2 . ASN A 1 376 ? 22.011 11.422 9.664 1.00 42.78 ? 408 ASN A ND2 1 ATOM 3043 N N . TYR A 1 377 ? 22.128 7.435 6.356 1.00 23.39 ? 409 TYR A N 1 ATOM 3044 C CA . TYR A 1 377 ? 22.836 6.637 5.387 1.00 22.91 ? 409 TYR A CA 1 ATOM 3045 C C . TYR A 1 377 ? 21.878 5.784 4.596 1.00 21.44 ? 409 TYR A C 1 ATOM 3046 O O . TYR A 1 377 ? 22.165 5.427 3.460 1.00 22.12 ? 409 TYR A O 1 ATOM 3047 C CB . TYR A 1 377 ? 23.865 5.747 6.070 1.00 24.90 ? 409 TYR A CB 1 ATOM 3048 C CG . TYR A 1 377 ? 25.041 6.488 6.680 1.00 27.46 ? 409 TYR A CG 1 ATOM 3049 C CD1 . TYR A 1 377 ? 25.368 7.789 6.285 1.00 28.88 ? 409 TYR A CD1 1 ATOM 3050 C CD2 . TYR A 1 377 ? 25.850 5.880 7.641 1.00 29.04 ? 409 TYR A CD2 1 ATOM 3051 C CE1 . TYR A 1 377 ? 26.439 8.462 6.841 1.00 29.00 ? 409 TYR A CE1 1 ATOM 3052 C CE2 . TYR A 1 377 ? 26.931 6.552 8.196 1.00 29.58 ? 409 TYR A CE2 1 ATOM 3053 C CZ . TYR A 1 377 ? 27.217 7.838 7.778 1.00 29.48 ? 409 TYR A CZ 1 ATOM 3054 O OH . TYR A 1 377 ? 28.291 8.520 8.284 1.00 32.28 ? 409 TYR A OH 1 ATOM 3055 N N . PHE A 1 378 ? 20.737 5.456 5.185 1.00 19.33 ? 410 PHE A N 1 ATOM 3056 C CA . PHE A 1 378 ? 19.701 4.678 4.496 1.00 17.44 ? 410 PHE A CA 1 ATOM 3057 C C . PHE A 1 378 ? 19.230 5.287 3.171 1.00 16.37 ? 410 PHE A C 1 ATOM 3058 O O . PHE A 1 378 ? 18.997 4.551 2.227 1.00 15.87 ? 410 PHE A O 1 ATOM 3059 C CB . PHE A 1 378 ? 18.512 4.524 5.420 1.00 16.78 ? 410 PHE A CB 1 ATOM 3060 C CG . PHE A 1 378 ? 17.364 3.783 4.817 1.00 16.32 ? 410 PHE A CG 1 ATOM 3061 C CD1 . PHE A 1 378 ? 17.436 2.423 4.607 1.00 16.24 ? 410 PHE A CD1 1 ATOM 3062 C CD2 . PHE A 1 378 ? 16.199 4.448 4.478 1.00 16.33 ? 410 PHE A CD2 1 ATOM 3063 C CE1 . PHE A 1 378 ? 16.361 1.733 4.078 1.00 16.17 ? 410 PHE A CE1 1 ATOM 3064 C CE2 . PHE A 1 378 ? 15.123 3.765 3.943 1.00 16.19 ? 410 PHE A CE2 1 ATOM 3065 C CZ . PHE A 1 378 ? 15.204 2.406 3.747 1.00 15.97 ? 410 PHE A CZ 1 ATOM 3066 N N . PHE A 1 379 ? 19.067 6.611 3.119 1.00 15.35 ? 411 PHE A N 1 ATOM 3067 C CA . PHE A 1 379 ? 18.779 7.329 1.868 1.00 14.70 ? 411 PHE A CA 1 ATOM 3068 C C . PHE A 1 379 ? 20.022 7.953 1.286 1.00 13.61 ? 411 PHE A C 1 ATOM 3069 O O . PHE A 1 379 ? 19.939 8.980 0.624 1.00 13.01 ? 411 PHE A O 1 ATOM 3070 C CB . PHE A 1 379 ? 17.812 8.479 2.100 1.00 15.30 ? 411 PHE A CB 1 ATOM 3071 C CG . PHE A 1 379 ? 16.526 8.073 2.704 1.00 16.11 ? 411 PHE A CG 1 ATOM 3072 C CD1 . PHE A 1 379 ? 15.520 7.533 1.916 1.00 16.26 ? 411 PHE A CD1 1 ATOM 3073 C CD2 . PHE A 1 379 ? 16.304 8.248 4.067 1.00 16.80 ? 411 PHE A CD2 1 ATOM 3074 C CE1 . PHE A 1 379 ? 14.310 7.155 2.479 1.00 16.71 ? 411 PHE A CE1 1 ATOM 3075 C CE2 . PHE A 1 379 ? 15.088 7.876 4.633 1.00 17.19 ? 411 PHE A CE2 1 ATOM 3076 C CZ . PHE A 1 379 ? 14.087 7.333 3.836 1.00 16.82 ? 411 PHE A CZ 1 ATOM 3077 N N . VAL A 1 380 ? 21.168 7.340 1.549 1.00 12.90 ? 412 VAL A N 1 ATOM 3078 C CA . VAL A 1 380 ? 22.467 7.804 1.058 1.00 12.46 ? 412 VAL A CA 1 ATOM 3079 C C . VAL A 1 380 ? 22.712 9.319 1.213 1.00 12.64 ? 412 VAL A C 1 ATOM 3080 O O . VAL A 1 380 ? 23.082 10.028 0.271 1.00 12.04 ? 412 VAL A O 1 ATOM 3081 C CB . VAL A 1 380 ? 22.699 7.368 -0.377 1.00 11.82 ? 412 VAL A CB 1 ATOM 3082 C CG1 . VAL A 1 380 ? 24.166 7.525 -0.699 1.00 11.88 ? 412 VAL A CG1 1 ATOM 3083 C CG2 . VAL A 1 380 ? 22.270 5.934 -0.553 1.00 11.59 ? 412 VAL A CG2 1 ATOM 3084 N N . SER A 1 381 ? 22.512 9.769 2.444 1.00 13.13 ? 413 SER A N 1 ATOM 3085 C CA . SER A 1 381 ? 22.777 11.132 2.881 1.00 14.06 ? 413 SER A CA 1 ATOM 3086 C C . SER A 1 381 ? 21.937 12.178 2.119 1.00 15.47 ? 413 SER A C 1 ATOM 3087 O O . SER A 1 381 ? 22.278 13.348 2.081 1.00 15.39 ? 413 SER A O 1 ATOM 3088 C CB . SER A 1 381 ? 24.291 11.434 2.826 1.00 13.76 ? 413 SER A CB 1 ATOM 3089 O OG . SER A 1 381 ? 25.074 10.671 3.755 1.00 13.14 ? 413 SER A OG 1 ATOM 3090 N N . TYR A 1 382 ? 20.799 11.760 1.587 1.00 17.56 ? 414 TYR A N 1 ATOM 3091 C CA . TYR A 1 382 ? 20.041 12.584 0.654 1.00 20.42 ? 414 TYR A CA 1 ATOM 3092 C C . TYR A 1 382 ? 19.453 13.879 1.234 1.00 24.61 ? 414 TYR A C 1 ATOM 3093 O O . TYR A 1 382 ? 19.656 14.956 0.684 1.00 26.33 ? 414 TYR A O 1 ATOM 3094 C CB . TYR A 1 382 ? 18.927 11.758 -0.032 1.00 19.81 ? 414 TYR A CB 1 ATOM 3095 C CG . TYR A 1 382 ? 17.965 12.619 -0.823 1.00 18.43 ? 414 TYR A CG 1 ATOM 3096 C CD1 . TYR A 1 382 ? 18.324 13.142 -2.052 1.00 17.64 ? 414 TYR A CD1 1 ATOM 3097 C CD2 . TYR A 1 382 ? 16.721 12.930 -0.311 1.00 17.67 ? 414 TYR A CD2 1 ATOM 3098 C CE1 . TYR A 1 382 ? 17.456 13.938 -2.750 1.00 17.49 ? 414 TYR A CE1 1 ATOM 3099 C CE2 . TYR A 1 382 ? 15.850 13.718 -1.000 1.00 17.49 ? 414 TYR A CE2 1 ATOM 3100 C CZ . TYR A 1 382 ? 16.222 14.223 -2.215 1.00 17.26 ? 414 TYR A CZ 1 ATOM 3101 O OH . TYR A 1 382 ? 15.329 15.007 -2.882 1.00 16.86 ? 414 TYR A OH 1 ATOM 3102 N N . ASP A 1 383 ? 18.660 13.775 2.283 1.00 30.41 ? 415 ASP A N 1 ATOM 3103 C CA . ASP A 1 383 ? 18.399 14.934 3.108 1.00 37.08 ? 415 ASP A CA 1 ATOM 3104 C C . ASP A 1 383 ? 19.017 14.483 4.388 1.00 40.93 ? 415 ASP A C 1 ATOM 3105 O O . ASP A 1 383 ? 18.970 13.264 4.705 1.00 44.19 ? 415 ASP A O 1 ATOM 3106 C CB . ASP A 1 383 ? 16.909 15.209 3.303 1.00 43.09 ? 415 ASP A CB 1 ATOM 3107 C CG . ASP A 1 383 ? 16.650 16.398 4.240 1.00 45.92 ? 415 ASP A CG 1 ATOM 3108 O OD1 . ASP A 1 383 ? 17.536 17.294 4.299 1.00 44.76 ? 415 ASP A OD1 1 ATOM 3109 O OD2 . ASP A 1 383 ? 15.573 16.426 4.907 1.00 45.25 -1 415 ASP A OD2 1 ATOM 3110 N N . SER A 1 384 ? 19.651 15.423 5.087 1.00 41.34 ? 416 SER A N 1 ATOM 3111 C CA . SER A 1 384 ? 20.300 15.077 6.332 1.00 45.80 ? 416 SER A CA 1 ATOM 3112 C C . SER A 1 384 ? 19.705 15.826 7.502 1.00 45.50 ? 416 SER A C 1 ATOM 3113 O O . SER A 1 384 ? 20.093 15.619 8.646 1.00 48.79 ? 416 SER A O 1 ATOM 3114 C CB . SER A 1 384 ? 21.833 15.177 6.213 1.00 49.42 ? 416 SER A CB 1 ATOM 3115 O OG . SER A 1 384 ? 22.381 13.913 5.771 1.00 50.07 ? 416 SER A OG 1 ATOM 3116 N N . SER A 1 385 ? 18.713 16.654 7.211 1.00 45.16 ? 417 SER A N 1 ATOM 3117 C CA . SER A 1 385 ? 17.771 17.110 8.226 1.00 44.97 ? 417 SER A CA 1 ATOM 3118 C C . SER A 1 385 ? 16.533 16.203 8.236 1.00 43.97 ? 417 SER A C 1 ATOM 3119 O O . SER A 1 385 ? 15.411 16.664 8.497 1.00 42.12 ? 417 SER A O 1 ATOM 3120 C CB . SER A 1 385 ? 17.337 18.538 7.920 1.00 45.87 ? 417 SER A CB 1 ATOM 3121 O OG . SER A 1 385 ? 16.347 18.539 6.905 1.00 46.54 ? 417 SER A OG 1 ATOM 3122 N N . VAL A 1 386 ? 16.732 14.923 7.937 1.00 42.87 ? 418 VAL A N 1 ATOM 3123 C CA . VAL A 1 386 ? 15.620 13.990 7.828 1.00 41.03 ? 418 VAL A CA 1 ATOM 3124 C C . VAL A 1 386 ? 15.466 13.306 9.170 1.00 36.51 ? 418 VAL A C 1 ATOM 3125 O O . VAL A 1 386 ? 16.413 13.220 9.913 1.00 39.03 ? 418 VAL A O 1 ATOM 3126 C CB . VAL A 1 386 ? 15.851 12.959 6.705 1.00 42.36 ? 418 VAL A CB 1 ATOM 3127 C CG1 . VAL A 1 386 ? 16.869 11.895 7.117 1.00 41.82 ? 418 VAL A CG1 1 ATOM 3128 C CG2 . VAL A 1 386 ? 14.525 12.317 6.313 1.00 44.36 ? 418 VAL A CG2 1 ATOM 3129 N N . THR A 1 387 ? 14.276 12.836 9.486 1.00 32.31 ? 419 THR A N 1 ATOM 3130 C CA . THR A 1 387 ? 14.005 12.304 10.805 1.00 29.60 ? 419 THR A CA 1 ATOM 3131 C C . THR A 1 387 ? 13.132 11.089 10.652 1.00 27.10 ? 419 THR A C 1 ATOM 3132 O O . THR A 1 387 ? 12.910 10.630 9.548 1.00 27.09 ? 419 THR A O 1 ATOM 3133 C CB . THR A 1 387 ? 13.337 13.371 11.702 1.00 30.21 ? 419 THR A CB 1 ATOM 3134 O OG1 . THR A 1 387 ? 13.003 12.795 12.965 1.00 30.61 ? 419 THR A OG1 1 ATOM 3135 C CG2 . THR A 1 387 ? 12.065 13.934 11.067 1.00 30.58 ? 419 THR A CG2 1 ATOM 3136 N N . CYS A 1 388 ? 12.615 10.572 11.752 1.00 26.23 ? 420 CYS A N 1 ATOM 3137 C CA . CYS A 1 388 ? 11.997 9.250 11.737 1.00 26.69 ? 420 CYS A CA 1 ATOM 3138 C C . CYS A 1 388 ? 11.230 9.001 13.022 1.00 25.26 ? 420 CYS A C 1 ATOM 3139 O O . CYS A 1 388 ? 11.799 9.134 14.075 1.00 26.64 ? 420 CYS A O 1 ATOM 3140 C CB . CYS A 1 388 ? 13.087 8.183 11.594 1.00 26.52 ? 420 CYS A CB 1 ATOM 3141 S SG . CYS A 1 388 ? 12.422 6.520 11.525 1.00 28.62 ? 420 CYS A SG 1 ATOM 3142 N N . ASP A 1 389 ? 9.957 8.641 12.951 1.00 23.73 ? 421 ASP A N 1 ATOM 3143 C CA . ASP A 1 389 ? 9.169 8.476 14.173 1.00 23.63 ? 421 ASP A CA 1 ATOM 3144 C C . ASP A 1 389 ? 9.319 7.055 14.738 1.00 23.10 ? 421 ASP A C 1 ATOM 3145 O O . ASP A 1 389 ? 9.984 6.235 14.132 1.00 21.74 ? 421 ASP A O 1 ATOM 3146 C CB . ASP A 1 389 ? 7.712 8.800 13.891 1.00 23.57 ? 421 ASP A CB 1 ATOM 3147 C CG . ASP A 1 389 ? 7.064 7.750 13.092 1.00 23.88 ? 421 ASP A CG 1 ATOM 3148 O OD1 . ASP A 1 389 ? 7.789 7.147 12.291 1.00 25.75 ? 421 ASP A OD1 1 ATOM 3149 O OD2 . ASP A 1 389 ? 5.865 7.499 13.257 1.00 24.38 -1 421 ASP A OD2 1 ATOM 3150 N N . LYS A 1 390 ? 8.698 6.781 15.886 1.00 24.43 ? 422 LYS A N 1 ATOM 3151 C CA . LYS A 1 390 ? 8.888 5.510 16.599 1.00 27.26 ? 422 LYS A CA 1 ATOM 3152 C C . LYS A 1 390 ? 8.523 4.316 15.733 1.00 26.37 ? 422 LYS A C 1 ATOM 3153 O O . LYS A 1 390 ? 9.135 3.245 15.828 1.00 26.47 ? 422 LYS A O 1 ATOM 3154 C CB . LYS A 1 390 ? 8.016 5.402 17.859 1.00 31.18 ? 422 LYS A CB 1 ATOM 3155 C CG . LYS A 1 390 ? 8.215 6.463 18.935 1.00 36.99 ? 422 LYS A CG 1 ATOM 3156 C CD . LYS A 1 390 ? 6.965 6.666 19.829 1.00 43.48 ? 422 LYS A CD 1 ATOM 3157 C CE . LYS A 1 390 ? 5.648 6.794 19.023 1.00 46.37 ? 422 LYS A CE 1 ATOM 3158 N NZ . LYS A 1 390 ? 4.457 7.382 19.714 1.00 46.57 1 422 LYS A NZ 1 ATOM 3159 N N . THR A 1 391 ? 7.499 4.489 14.914 1.00 23.99 ? 423 THR A N 1 ATOM 3160 C CA . THR A 1 391 ? 6.963 3.389 14.152 1.00 23.23 ? 423 THR A CA 1 ATOM 3161 C C . THR A 1 391 ? 7.862 3.032 12.959 1.00 22.97 ? 423 THR A C 1 ATOM 3162 O O . THR A 1 391 ? 8.235 1.866 12.765 1.00 21.64 ? 423 THR A O 1 ATOM 3163 C CB . THR A 1 391 ? 5.561 3.768 13.700 1.00 23.44 ? 423 THR A CB 1 ATOM 3164 O OG1 . THR A 1 391 ? 4.879 4.330 14.823 1.00 23.26 ? 423 THR A OG1 1 ATOM 3165 C CG2 . THR A 1 391 ? 4.807 2.567 13.195 1.00 23.58 ? 423 THR A CG2 1 ATOM 3166 N N . CYS A 1 392 ? 8.229 4.040 12.177 1.00 22.85 ? 424 CYS A N 1 ATOM 3167 C CA . CYS A 1 392 ? 9.191 3.830 11.111 1.00 24.36 ? 424 CYS A CA 1 ATOM 3168 C C . CYS A 1 392 ? 10.430 3.146 11.638 1.00 21.93 ? 424 CYS A C 1 ATOM 3169 O O . CYS A 1 392 ? 10.869 2.149 11.065 1.00 22.24 ? 424 CYS A O 1 ATOM 3170 C CB . CYS A 1 392 ? 9.552 5.139 10.407 1.00 27.11 ? 424 CYS A CB 1 ATOM 3171 S SG . CYS A 1 392 ? 8.312 5.528 9.127 1.00 35.69 ? 424 CYS A SG 1 ATOM 3172 N N . LYS A 1 393 ? 10.959 3.660 12.745 1.00 18.95 ? 425 LYS A N 1 ATOM 3173 C CA . LYS A 1 393 ? 12.114 3.058 13.375 1.00 17.28 ? 425 LYS A CA 1 ATOM 3174 C C . LYS A 1 393 ? 11.860 1.640 13.786 1.00 16.57 ? 425 LYS A C 1 ATOM 3175 O O . LYS A 1 393 ? 12.746 0.816 13.699 1.00 16.76 ? 425 LYS A O 1 ATOM 3176 C CB . LYS A 1 393 ? 12.555 3.835 14.605 1.00 16.67 ? 425 LYS A CB 1 ATOM 3177 C CG . LYS A 1 393 ? 13.586 3.108 15.462 1.00 16.14 ? 425 LYS A CG 1 ATOM 3178 C CD . LYS A 1 393 ? 14.426 4.065 16.271 1.00 15.80 ? 425 LYS A CD 1 ATOM 3179 C CE . LYS A 1 393 ? 14.986 3.424 17.537 1.00 15.82 ? 425 LYS A CE 1 ATOM 3180 N NZ . LYS A 1 393 ? 15.987 4.337 18.171 1.00 15.96 1 425 LYS A NZ 1 ATOM 3181 N N . ALA A 1 394 ? 10.674 1.344 14.267 1.00 15.89 ? 426 ALA A N 1 ATOM 3182 C CA . ALA A 1 394 ? 10.395 -0.016 14.650 1.00 16.15 ? 426 ALA A CA 1 ATOM 3183 C C . ALA A 1 394 ? 10.435 -0.905 13.431 1.00 16.52 ? 426 ALA A C 1 ATOM 3184 O O . ALA A 1 394 ? 10.946 -2.017 13.457 1.00 16.18 ? 426 ALA A O 1 ATOM 3185 C CB . ALA A 1 394 ? 9.040 -0.096 15.289 1.00 16.45 ? 426 ALA A CB 1 ATOM 3186 N N . PHE A 1 395 ? 9.880 -0.403 12.348 1.00 17.41 ? 427 PHE A N 1 ATOM 3187 C CA . PHE A 1 395 ? 9.812 -1.187 11.143 1.00 18.48 ? 427 PHE A CA 1 ATOM 3188 C C . PHE A 1 395 ? 11.181 -1.444 10.566 1.00 17.67 ? 427 PHE A C 1 ATOM 3189 O O . PHE A 1 395 ? 11.359 -2.406 9.819 1.00 18.96 ? 427 PHE A O 1 ATOM 3190 C CB . PHE A 1 395 ? 8.968 -0.477 10.076 1.00 19.98 ? 427 PHE A CB 1 ATOM 3191 C CG . PHE A 1 395 ? 7.507 -0.415 10.387 1.00 20.48 ? 427 PHE A CG 1 ATOM 3192 C CD1 . PHE A 1 395 ? 6.906 -1.337 11.249 1.00 20.88 ? 427 PHE A CD1 1 ATOM 3193 C CD2 . PHE A 1 395 ? 6.725 0.562 9.782 1.00 20.94 ? 427 PHE A CD2 1 ATOM 3194 C CE1 . PHE A 1 395 ? 5.552 -1.265 11.513 1.00 21.73 ? 427 PHE A CE1 1 ATOM 3195 C CE2 . PHE A 1 395 ? 5.379 0.649 10.043 1.00 21.03 ? 427 PHE A CE2 1 ATOM 3196 C CZ . PHE A 1 395 ? 4.789 -0.270 10.907 1.00 21.89 ? 427 PHE A CZ 1 ATOM 3197 N N . GLN A 1 396 ? 12.114 -0.549 10.843 1.00 16.56 ? 428 GLN A N 1 ATOM 3198 C CA . GLN A 1 396 ? 13.485 -0.715 10.401 1.00 16.29 ? 428 GLN A CA 1 ATOM 3199 C C . GLN A 1 396 ? 14.152 -1.761 11.264 1.00 16.42 ? 428 GLN A C 1 ATOM 3200 O O . GLN A 1 396 ? 14.716 -2.728 10.759 1.00 16.29 ? 428 GLN A O 1 ATOM 3201 C CB . GLN A 1 396 ? 14.258 0.595 10.546 1.00 16.20 ? 428 GLN A CB 1 ATOM 3202 C CG . GLN A 1 396 ? 13.996 1.632 9.471 1.00 15.83 ? 428 GLN A CG 1 ATOM 3203 C CD . GLN A 1 396 ? 14.782 1.407 8.203 1.00 15.81 ? 428 GLN A CD 1 ATOM 3204 O OE1 . GLN A 1 396 ? 15.711 0.588 8.142 1.00 16.60 ? 428 GLN A OE1 1 ATOM 3205 N NE2 . GLN A 1 396 ? 14.413 2.132 7.167 1.00 15.96 ? 428 GLN A NE2 1 ATOM 3206 N N . ILE A 1 397 ? 14.077 -1.563 12.575 1.00 16.84 ? 429 ILE A N 1 ATOM 3207 C CA . ILE A 1 397 ? 14.761 -2.434 13.516 1.00 17.71 ? 429 ILE A CA 1 ATOM 3208 C C . ILE A 1 397 ? 14.353 -3.867 13.283 1.00 17.90 ? 429 ILE A C 1 ATOM 3209 O O . ILE A 1 397 ? 15.200 -4.709 13.035 1.00 18.16 ? 429 ILE A O 1 ATOM 3210 C CB . ILE A 1 397 ? 14.450 -2.087 14.987 1.00 18.36 ? 429 ILE A CB 1 ATOM 3211 C CG1 . ILE A 1 397 ? 15.012 -0.713 15.351 1.00 18.54 ? 429 ILE A CG1 1 ATOM 3212 C CG2 . ILE A 1 397 ? 15.015 -3.146 15.941 1.00 18.47 ? 429 ILE A CG2 1 ATOM 3213 C CD1 . ILE A 1 397 ? 16.494 -0.558 15.122 1.00 18.53 ? 429 ILE A CD1 1 ATOM 3214 N N . CYS A 1 398 ? 13.063 -4.146 13.355 1.00 17.92 ? 430 CYS A N 1 ATOM 3215 C CA . CYS A 1 398 ? 12.618 -5.502 13.165 1.00 18.43 ? 430 CYS A CA 1 ATOM 3216 C C . CYS A 1 398 ? 13.115 -6.093 11.853 1.00 17.11 ? 430 CYS A C 1 ATOM 3217 O O . CYS A 1 398 ? 13.417 -7.280 11.802 1.00 16.56 ? 430 CYS A O 1 ATOM 3218 C CB . CYS A 1 398 ? 11.103 -5.587 13.233 1.00 20.41 ? 430 CYS A CB 1 ATOM 3219 S SG . CYS A 1 398 ? 10.454 -5.359 14.902 1.00 24.52 ? 430 CYS A SG 1 ATOM 3220 N N . ALA A 1 399 ? 13.195 -5.277 10.801 1.00 15.83 ? 431 ALA A N 1 ATOM 3221 C CA . ALA A 1 399 ? 13.613 -5.762 9.501 1.00 15.07 ? 431 ALA A CA 1 ATOM 3222 C C . ALA A 1 399 ? 15.055 -6.175 9.564 1.00 15.12 ? 431 ALA A C 1 ATOM 3223 O O . ALA A 1 399 ? 15.421 -7.245 9.097 1.00 15.35 ? 431 ALA A O 1 ATOM 3224 C CB . ALA A 1 399 ? 13.437 -4.698 8.464 1.00 14.90 ? 431 ALA A CB 1 ATOM 3225 N N . ILE A 1 400 ? 15.873 -5.341 10.179 1.00 15.16 ? 432 ILE A N 1 ATOM 3226 C CA . ILE A 1 400 ? 17.298 -5.632 10.303 1.00 15.64 ? 432 ILE A CA 1 ATOM 3227 C C . ILE A 1 400 ? 17.612 -6.909 11.073 1.00 16.28 ? 432 ILE A C 1 ATOM 3228 O O . ILE A 1 400 ? 18.591 -7.572 10.788 1.00 16.08 ? 432 ILE A O 1 ATOM 3229 C CB . ILE A 1 400 ? 18.025 -4.496 11.022 1.00 15.32 ? 432 ILE A CB 1 ATOM 3230 C CG1 . ILE A 1 400 ? 17.883 -3.213 10.218 1.00 15.31 ? 432 ILE A CG1 1 ATOM 3231 C CG2 . ILE A 1 400 ? 19.504 -4.822 11.179 1.00 15.30 ? 432 ILE A CG2 1 ATOM 3232 C CD1 . ILE A 1 400 ? 18.017 -1.968 11.049 1.00 15.37 ? 432 ILE A CD1 1 ATOM 3233 N N . MET A 1 401 ? 16.788 -7.234 12.060 1.00 17.98 ? 433 MET A N 1 ATOM 3234 C CA . MET A 1 401 ? 17.069 -8.326 12.987 1.00 18.93 ? 433 MET A CA 1 ATOM 3235 C C . MET A 1 401 ? 16.226 -9.539 12.770 1.00 18.38 ? 433 MET A C 1 ATOM 3236 O O . MET A 1 401 ? 16.530 -10.570 13.333 1.00 19.53 ? 433 MET A O 1 ATOM 3237 C CB . MET A 1 401 ? 16.869 -7.868 14.425 1.00 20.54 ? 433 MET A CB 1 ATOM 3238 C CG . MET A 1 401 ? 18.125 -7.299 15.054 1.00 22.39 ? 433 MET A CG 1 ATOM 3239 S SD . MET A 1 401 ? 17.739 -6.046 16.297 1.00 27.39 ? 433 MET A SD 1 ATOM 3240 C CE . MET A 1 401 ? 18.983 -6.532 17.502 1.00 27.90 ? 433 MET A CE 1 ATOM 3241 N N . ASN A 1 402 ? 15.165 -9.436 11.986 1.00 18.00 ? 434 ASN A N 1 ATOM 3242 C CA . ASN A 1 402 ? 14.296 -10.580 11.749 1.00 17.87 ? 434 ASN A CA 1 ATOM 3243 C C . ASN A 1 402 ? 13.959 -10.755 10.273 1.00 18.85 ? 434 ASN A C 1 ATOM 3244 O O . ASN A 1 402 ? 13.463 -9.839 9.587 1.00 18.92 ? 434 ASN A O 1 ATOM 3245 C CB . ASN A 1 402 ? 13.062 -10.479 12.628 1.00 17.50 ? 434 ASN A CB 1 ATOM 3246 C CG . ASN A 1 402 ? 13.421 -10.127 14.056 1.00 16.84 ? 434 ASN A CG 1 ATOM 3247 O OD1 . ASN A 1 402 ? 13.773 -10.990 14.853 1.00 16.95 ? 434 ASN A OD1 1 ATOM 3248 N ND2 . ASN A 1 402 ? 13.388 -8.849 14.366 1.00 16.56 ? 434 ASN A ND2 1 ATOM 3249 N N . LEU A 1 403 ? 14.296 -11.945 9.790 1.00 20.22 ? 435 LEU A N 1 ATOM 3250 C CA . LEU A 1 403 ? 14.260 -12.250 8.383 1.00 21.01 ? 435 LEU A CA 1 ATOM 3251 C C . LEU A 1 403 ? 13.116 -13.144 8.019 1.00 22.95 ? 435 LEU A C 1 ATOM 3252 O O . LEU A 1 403 ? 12.640 -13.054 6.908 1.00 23.28 ? 435 LEU A O 1 ATOM 3253 C CB . LEU A 1 403 ? 15.564 -12.898 7.966 1.00 20.59 ? 435 LEU A CB 1 ATOM 3254 C CG . LEU A 1 403 ? 16.526 -11.870 7.394 1.00 21.06 ? 435 LEU A CG 1 ATOM 3255 C CD1 . LEU A 1 403 ? 16.962 -10.875 8.447 1.00 21.35 ? 435 LEU A CD1 1 ATOM 3256 C CD2 . LEU A 1 403 ? 17.737 -12.558 6.802 1.00 21.65 ? 435 LEU A CD2 1 ATOM 3257 N N . ASP A 1 404 ? 12.707 -14.031 8.932 1.00 26.42 ? 436 ASP A N 1 ATOM 3258 C CA . ASP A 1 404 ? 11.596 -14.966 8.701 1.00 28.21 ? 436 ASP A CA 1 ATOM 3259 C C . ASP A 1 404 ? 10.445 -14.451 9.514 1.00 28.30 ? 436 ASP A C 1 ATOM 3260 O O . ASP A 1 404 ? 10.650 -13.609 10.366 1.00 29.65 ? 436 ASP A O 1 ATOM 3261 C CB . ASP A 1 404 ? 11.972 -16.390 9.113 1.00 29.98 ? 436 ASP A CB 1 ATOM 3262 C CG . ASP A 1 404 ? 12.200 -16.527 10.604 1.00 33.05 ? 436 ASP A CG 1 ATOM 3263 O OD1 . ASP A 1 404 ? 11.191 -16.452 11.366 1.00 35.99 ? 436 ASP A OD1 1 ATOM 3264 O OD2 . ASP A 1 404 ? 13.386 -16.706 11.010 1.00 33.97 -1 436 ASP A OD2 1 ATOM 3265 N N . ASN A 1 405 ? 9.246 -14.956 9.288 1.00 29.63 ? 437 ASN A N 1 ATOM 3266 C CA . ASN A 1 405 ? 8.071 -14.232 9.757 1.00 32.08 ? 437 ASN A CA 1 ATOM 3267 C C . ASN A 1 405 ? 7.719 -14.462 11.199 1.00 31.09 ? 437 ASN A C 1 ATOM 3268 O O . ASN A 1 405 ? 7.043 -13.623 11.800 1.00 30.51 ? 437 ASN A O 1 ATOM 3269 C CB . ASN A 1 405 ? 6.836 -14.529 8.909 1.00 35.87 ? 437 ASN A CB 1 ATOM 3270 C CG . ASN A 1 405 ? 5.918 -15.534 9.554 1.00 38.57 ? 437 ASN A CG 1 ATOM 3271 O OD1 . ASN A 1 405 ? 4.736 -15.242 9.805 1.00 38.17 ? 437 ASN A OD1 1 ATOM 3272 N ND2 . ASN A 1 405 ? 6.460 -16.729 9.852 1.00 40.65 ? 437 ASN A ND2 1 ATOM 3273 N N . ILE A 1 406 ? 8.126 -15.603 11.742 1.00 29.89 ? 438 ILE A N 1 ATOM 3274 C CA . ILE A 1 406 ? 7.887 -15.863 13.146 1.00 30.45 ? 438 ILE A CA 1 ATOM 3275 C C . ILE A 1 406 ? 8.552 -14.715 13.898 1.00 28.44 ? 438 ILE A C 1 ATOM 3276 O O . ILE A 1 406 ? 7.895 -13.868 14.521 1.00 26.59 ? 438 ILE A O 1 ATOM 3277 C CB . ILE A 1 406 ? 8.476 -17.234 13.583 1.00 32.89 ? 438 ILE A CB 1 ATOM 3278 C CG1 . ILE A 1 406 ? 7.527 -18.378 13.206 1.00 33.72 ? 438 ILE A CG1 1 ATOM 3279 C CG2 . ILE A 1 406 ? 8.768 -17.292 15.082 1.00 33.67 ? 438 ILE A CG2 1 ATOM 3280 C CD1 . ILE A 1 406 ? 6.250 -18.452 14.027 1.00 34.23 ? 438 ILE A CD1 1 ATOM 3281 N N . SER A 1 407 ? 9.868 -14.681 13.791 1.00 26.34 ? 439 SER A N 1 ATOM 3282 C CA . SER A 1 407 ? 10.660 -13.728 14.527 1.00 25.62 ? 439 SER A CA 1 ATOM 3283 C C . SER A 1 407 ? 10.354 -12.255 14.169 1.00 24.26 ? 439 SER A C 1 ATOM 3284 O O . SER A 1 407 ? 10.548 -11.378 15.009 1.00 23.52 ? 439 SER A O 1 ATOM 3285 C CB . SER A 1 407 ? 12.108 -14.058 14.277 1.00 25.58 ? 439 SER A CB 1 ATOM 3286 O OG . SER A 1 407 ? 12.210 -14.455 12.924 1.00 27.26 ? 439 SER A OG 1 ATOM 3287 N N . TYR A 1 408 ? 9.881 -11.987 12.950 1.00 22.66 ? 440 TYR A N 1 ATOM 3288 C CA . TYR A 1 408 ? 9.493 -10.635 12.571 1.00 22.24 ? 440 TYR A CA 1 ATOM 3289 C C . TYR A 1 408 ? 8.235 -10.184 13.243 1.00 23.43 ? 440 TYR A C 1 ATOM 3290 O O . TYR A 1 408 ? 8.082 -9.016 13.502 1.00 23.53 ? 440 TYR A O 1 ATOM 3291 C CB . TYR A 1 408 ? 9.236 -10.516 11.092 1.00 21.74 ? 440 TYR A CB 1 ATOM 3292 C CG . TYR A 1 408 ? 8.920 -9.104 10.663 1.00 20.69 ? 440 TYR A CG 1 ATOM 3293 C CD1 . TYR A 1 408 ? 9.931 -8.186 10.489 1.00 20.18 ? 440 TYR A CD1 1 ATOM 3294 C CD2 . TYR A 1 408 ? 7.611 -8.684 10.434 1.00 20.24 ? 440 TYR A CD2 1 ATOM 3295 C CE1 . TYR A 1 408 ? 9.659 -6.887 10.086 1.00 20.12 ? 440 TYR A CE1 1 ATOM 3296 C CE2 . TYR A 1 408 ? 7.327 -7.375 10.037 1.00 19.61 ? 440 TYR A CE2 1 ATOM 3297 C CZ . TYR A 1 408 ? 8.361 -6.477 9.861 1.00 19.40 ? 440 TYR A CZ 1 ATOM 3298 O OH . TYR A 1 408 ? 8.169 -5.171 9.454 1.00 18.75 ? 440 TYR A OH 1 ATOM 3299 N N . ALA A 1 409 ? 7.308 -11.094 13.475 1.00 26.04 ? 441 ALA A N 1 ATOM 3300 C CA . ALA A 1 409 ? 6.083 -10.743 14.189 1.00 28.33 ? 441 ALA A CA 1 ATOM 3301 C C . ALA A 1 409 ? 6.329 -10.627 15.696 1.00 30.94 ? 441 ALA A C 1 ATOM 3302 O O . ALA A 1 409 ? 5.842 -9.703 16.323 1.00 30.76 ? 441 ALA A O 1 ATOM 3303 C CB . ALA A 1 409 ? 4.996 -11.762 13.901 1.00 28.51 ? 441 ALA A CB 1 ATOM 3304 N N . ASP A 1 410 ? 7.087 -11.558 16.275 1.00 34.75 ? 442 ASP A N 1 ATOM 3305 C CA . ASP A 1 410 ? 7.466 -11.457 17.677 1.00 37.54 ? 442 ASP A CA 1 ATOM 3306 C C . ASP A 1 410 ? 7.998 -10.034 17.924 1.00 35.17 ? 442 ASP A C 1 ATOM 3307 O O . ASP A 1 410 ? 7.666 -9.376 18.921 1.00 33.39 ? 442 ASP A O 1 ATOM 3308 C CB . ASP A 1 410 ? 8.522 -12.531 18.033 1.00 43.07 ? 442 ASP A CB 1 ATOM 3309 C CG . ASP A 1 410 ? 8.670 -12.768 19.571 1.00 51.51 ? 442 ASP A CG 1 ATOM 3310 O OD1 . ASP A 1 410 ? 7.686 -12.642 20.353 1.00 55.88 ? 442 ASP A OD1 1 ATOM 3311 O OD2 . ASP A 1 410 ? 9.791 -13.103 20.007 1.00 54.42 -1 442 ASP A OD2 1 ATOM 3312 N N . CYS A 1 411 ? 8.798 -9.552 16.981 1.00 33.61 ? 443 CYS A N 1 ATOM 3313 C CA . CYS A 1 411 ? 9.500 -8.279 17.142 1.00 33.76 ? 443 CYS A CA 1 ATOM 3314 C C . CYS A 1 411 ? 8.556 -7.102 17.021 1.00 36.89 ? 443 CYS A C 1 ATOM 3315 O O . CYS A 1 411 ? 8.738 -6.047 17.640 1.00 39.09 ? 443 CYS A O 1 ATOM 3316 C CB . CYS A 1 411 ? 10.606 -8.167 16.096 1.00 30.95 ? 443 CYS A CB 1 ATOM 3317 S SG . CYS A 1 411 ? 11.532 -6.625 16.123 1.00 27.20 ? 443 CYS A SG 1 ATOM 3318 N N . LEU A 1 412 ? 7.557 -7.299 16.191 1.00 41.27 ? 444 LEU A N 1 ATOM 3319 C CA . LEU A 1 412 ? 6.530 -6.322 15.968 1.00 45.41 ? 444 LEU A CA 1 ATOM 3320 C C . LEU A 1 412 ? 5.544 -6.276 17.135 1.00 49.63 ? 444 LEU A C 1 ATOM 3321 O O . LEU A 1 412 ? 5.153 -5.197 17.568 1.00 50.55 ? 444 LEU A O 1 ATOM 3322 C CB . LEU A 1 412 ? 5.796 -6.705 14.695 1.00 46.34 ? 444 LEU A CB 1 ATOM 3323 C CG . LEU A 1 412 ? 5.490 -5.589 13.724 1.00 49.00 ? 444 LEU A CG 1 ATOM 3324 C CD1 . LEU A 1 412 ? 6.716 -4.718 13.468 1.00 48.60 ? 444 LEU A CD1 1 ATOM 3325 C CD2 . LEU A 1 412 ? 4.905 -6.218 12.457 1.00 51.00 ? 444 LEU A CD2 1 ATOM 3326 N N . LYS A 1 413 ? 5.071 -7.425 17.553 1.00 55.02 ? 445 LYS A N 1 ATOM 3327 C CA . LYS A 1 413 ? 4.086 -7.454 18.603 1.00 61.75 ? 445 LYS A CA 1 ATOM 3328 C C . LYS A 1 413 ? 4.748 -7.021 19.847 1.00 60.47 ? 445 LYS A C 1 ATOM 3329 O O . LYS A 1 413 ? 4.216 -6.266 20.621 1.00 66.42 ? 445 LYS A O 1 ATOM 3330 C CB . LYS A 1 413 ? 3.431 -8.829 18.704 1.00 69.33 ? 445 LYS A CB 1 ATOM 3331 C CG . LYS A 1 413 ? 3.779 -9.688 19.892 1.00 76.36 ? 445 LYS A CG 1 ATOM 3332 C CD . LYS A 1 413 ? 3.004 -10.984 19.885 1.00 82.52 ? 445 LYS A CD 1 ATOM 3333 C CE . LYS A 1 413 ? 3.028 -11.655 18.531 1.00 86.44 ? 445 LYS A CE 1 ATOM 3334 N NZ . LYS A 1 413 ? 3.618 -13.016 18.596 1.00 89.13 1 445 LYS A NZ 1 ATOM 3335 N N . GLN A 1 414 ? 5.921 -7.536 20.038 1.00 56.36 ? 446 GLN A N 1 ATOM 3336 C CA . GLN A 1 414 ? 6.647 -7.189 21.188 1.00 55.74 ? 446 GLN A CA 1 ATOM 3337 C C . GLN A 1 414 ? 6.451 -5.717 21.400 1.00 59.96 ? 446 GLN A C 1 ATOM 3338 O O . GLN A 1 414 ? 6.384 -5.321 22.526 1.00 67.21 ? 446 GLN A O 1 ATOM 3339 C CB . GLN A 1 414 ? 8.020 -7.834 21.096 1.00 53.65 ? 446 GLN A CB 1 ATOM 3340 C CG . GLN A 1 414 ? 9.180 -7.070 21.682 1.00 54.17 ? 446 GLN A CG 1 ATOM 3341 C CD . GLN A 1 414 ? 9.821 -7.763 22.843 1.00 56.70 ? 446 GLN A CD 1 ATOM 3342 O OE1 . GLN A 1 414 ? 10.210 -8.914 22.751 1.00 52.04 ? 446 GLN A OE1 1 ATOM 3343 N NE2 . GLN A 1 414 ? 9.967 -7.048 23.933 1.00 56.84 ? 446 GLN A NE2 1 ATOM 3344 N N . LEU A 1 415 ? 6.335 -4.902 20.350 1.00 60.32 ? 447 LEU A N 1 ATOM 3345 C CA . LEU A 1 415 ? 6.168 -3.442 20.524 1.00 59.12 ? 447 LEU A CA 1 ATOM 3346 C C . LEU A 1 415 ? 5.658 -2.531 19.354 1.00 61.70 ? 447 LEU A C 1 ATOM 3347 O O . LEU A 1 415 ? 6.460 -1.863 18.729 1.00 65.82 ? 447 LEU A O 1 ATOM 3348 C CB . LEU A 1 415 ? 7.644 -3.064 20.775 1.00 57.09 ? 447 LEU A CB 1 ATOM 3349 C CG . LEU A 1 415 ? 8.465 -3.457 19.550 1.00 52.72 ? 447 LEU A CG 1 ATOM 3350 C CD1 . LEU A 1 415 ? 9.123 -2.233 18.969 1.00 50.41 ? 447 LEU A CD1 1 ATOM 3351 C CD2 . LEU A 1 415 ? 9.466 -4.578 19.763 1.00 52.87 ? 447 LEU A CD2 1 ATOM 3352 N N . TYR A 1 416 ? 4.385 -2.399 18.993 1.00 61.64 ? 448 TYR A N 1 ATOM 3353 C CA . TYR A 1 416 ? 3.179 -3.021 19.442 1.00 63.20 ? 448 TYR A CA 1 ATOM 3354 C C . TYR A 1 416 ? 2.394 -3.065 18.110 1.00 68.39 ? 448 TYR A C 1 ATOM 3355 O O . TYR A 1 416 ? 2.832 -2.461 17.152 1.00 68.17 ? 448 TYR A O 1 ATOM 3356 C CB . TYR A 1 416 ? 2.510 -2.107 20.409 1.00 63.75 ? 448 TYR A CB 1 ATOM 3357 C CG . TYR A 1 416 ? 2.672 -2.515 21.837 1.00 66.88 ? 448 TYR A CG 1 ATOM 3358 C CD1 . TYR A 1 416 ? 2.203 -3.733 22.294 1.00 68.09 ? 448 TYR A CD1 1 ATOM 3359 C CD2 . TYR A 1 416 ? 3.281 -1.686 22.728 1.00 66.84 ? 448 TYR A CD2 1 ATOM 3360 C CE1 . TYR A 1 416 ? 2.349 -4.101 23.612 1.00 66.91 ? 448 TYR A CE1 1 ATOM 3361 C CE2 . TYR A 1 416 ? 3.430 -2.050 24.033 1.00 65.37 ? 448 TYR A CE2 1 ATOM 3362 C CZ . TYR A 1 416 ? 2.957 -3.250 24.468 1.00 65.36 ? 448 TYR A CZ 1 ATOM 3363 O OH . TYR A 1 416 ? 3.130 -3.568 25.779 1.00 60.95 ? 448 TYR A OH 1 ATOM 3364 N N . ILE A 1 417 ? 1.257 -3.758 18.017 1.00 75.03 ? 449 ILE A N 1 ATOM 3365 C CA . ILE A 1 417 ? 0.510 -3.913 16.703 1.00 74.73 ? 449 ILE A CA 1 ATOM 3366 C C . ILE A 1 417 ? -1.039 -3.964 16.713 1.00 77.10 ? 449 ILE A C 1 ATOM 3367 O O . ILE A 1 417 ? -1.648 -4.504 17.639 1.00 79.16 ? 449 ILE A O 1 ATOM 3368 C CB . ILE A 1 417 ? 1.021 -5.165 15.930 1.00 69.35 ? 449 ILE A CB 1 ATOM 3369 C CG1 . ILE A 1 417 ? 2.523 -5.049 15.745 1.00 67.40 ? 449 ILE A CG1 1 ATOM 3370 C CG2 . ILE A 1 417 ? 0.336 -5.337 14.568 1.00 67.31 ? 449 ILE A CG2 1 ATOM 3371 C CD1 . ILE A 1 417 ? 2.970 -3.746 15.094 1.00 66.38 ? 449 ILE A CD1 1 ATOM 3372 N N . LYS A 1 418 ? -1.652 -3.417 15.651 1.00 74.01 ? 450 LYS A N 1 ATOM 3373 C CA . LYS A 1 418 ? -3.106 -3.451 15.451 1.00 69.79 ? 450 LYS A CA 1 ATOM 3374 C C . LYS A 1 418 ? -3.740 -4.745 15.976 1.00 74.24 ? 450 LYS A C 1 ATOM 3375 O O . LYS A 1 418 ? -4.091 -4.841 17.164 1.00 69.62 ? 450 LYS A O 1 ATOM 3376 C CB . LYS A 1 418 ? -3.455 -3.237 13.966 1.00 63.17 ? 450 LYS A CB 1 ATOM 3377 C CG . LYS A 1 418 ? -3.835 -1.798 13.649 1.00 58.31 ? 450 LYS A CG 1 ATOM 3378 C CD . LYS A 1 418 ? -5.307 -1.510 13.962 1.00 54.78 ? 450 LYS A CD 1 ATOM 3379 C CE . LYS A 1 418 ? -5.558 -0.089 14.484 1.00 51.29 ? 450 LYS A CE 1 ATOM 3380 N NZ . LYS A 1 418 ? -6.683 0.623 13.795 1.00 48.32 1 450 LYS A NZ 1 ATOM 3381 N N . PRO B 2 1 ? 60.418 2.716 15.954 1.00 121.00 ? 33 PRO B N 1 ATOM 3382 C CA . PRO B 2 1 ? 59.397 1.915 15.264 1.00 119.93 ? 33 PRO B CA 1 ATOM 3383 C C . PRO B 2 1 ? 59.601 1.966 13.741 1.00 119.47 ? 33 PRO B C 1 ATOM 3384 O O . PRO B 2 1 ? 60.235 2.910 13.263 1.00 114.10 ? 33 PRO B O 1 ATOM 3385 C CB . PRO B 2 1 ? 58.075 2.586 15.680 1.00 118.52 ? 33 PRO B CB 1 ATOM 3386 C CG . PRO B 2 1 ? 58.404 3.399 16.897 1.00 118.67 ? 33 PRO B CG 1 ATOM 3387 C CD . PRO B 2 1 ? 59.833 3.826 16.726 1.00 119.55 ? 33 PRO B CD 1 ATOM 3388 N N . PRO B 2 2 ? 59.069 0.994 13.008 1.00 120.28 ? 34 PRO B N 1 ATOM 3389 C CA . PRO B 2 2 ? 59.206 0.960 11.552 1.00 116.78 ? 34 PRO B CA 1 ATOM 3390 C C . PRO B 2 2 ? 58.463 2.091 10.886 1.00 110.14 ? 34 PRO B C 1 ATOM 3391 O O . PRO B 2 2 ? 57.416 2.481 11.387 1.00 110.34 ? 34 PRO B O 1 ATOM 3392 C CB . PRO B 2 2 ? 58.537 -0.351 11.177 1.00 113.92 ? 34 PRO B CB 1 ATOM 3393 C CG . PRO B 2 2 ? 57.615 -0.670 12.312 1.00 114.72 ? 34 PRO B CG 1 ATOM 3394 C CD . PRO B 2 2 ? 57.877 0.269 13.452 1.00 116.93 ? 34 PRO B CD 1 ATOM 3395 N N . PRO B 2 3 ? 58.961 2.614 9.774 1.00 102.21 ? 35 PRO B N 1 ATOM 3396 C CA . PRO B 2 3 ? 58.275 3.723 9.100 1.00 94.53 ? 35 PRO B CA 1 ATOM 3397 C C . PRO B 2 3 ? 57.669 3.402 7.743 1.00 88.24 ? 35 PRO B C 1 ATOM 3398 O O . PRO B 2 3 ? 56.722 4.027 7.301 1.00 75.33 ? 35 PRO B O 1 ATOM 3399 C CB . PRO B 2 3 ? 59.404 4.704 8.846 1.00 94.69 ? 35 PRO B CB 1 ATOM 3400 C CG . PRO B 2 3 ? 60.608 3.854 8.774 1.00 98.45 ? 35 PRO B CG 1 ATOM 3401 C CD . PRO B 2 3 ? 60.402 2.863 9.865 1.00 102.03 ? 35 PRO B CD 1 ATOM 3402 N N . ALA B 2 4 ? 58.246 2.419 7.086 1.00 87.40 ? 36 ALA B N 1 ATOM 3403 C CA . ALA B 2 4 ? 57.799 1.995 5.781 1.00 82.77 ? 36 ALA B CA 1 ATOM 3404 C C . ALA B 2 4 ? 58.186 0.561 5.744 1.00 81.29 ? 36 ALA B C 1 ATOM 3405 O O . ALA B 2 4 ? 59.225 0.207 6.244 1.00 80.70 ? 36 ALA B O 1 ATOM 3406 C CB . ALA B 2 4 ? 58.492 2.737 4.667 1.00 81.23 ? 36 ALA B CB 1 ATOM 3407 N N . ILE B 2 5 ? 57.362 -0.285 5.155 1.00 76.46 ? 37 ILE B N 1 ATOM 3408 C CA . ILE B 2 5 ? 57.711 -1.718 5.128 1.00 66.94 ? 37 ILE B CA 1 ATOM 3409 C C . ILE B 2 5 ? 58.256 -2.107 3.743 1.00 64.33 ? 37 ILE B C 1 ATOM 3410 O O . ILE B 2 5 ? 57.553 -2.002 2.739 1.00 62.91 ? 37 ILE B O 1 ATOM 3411 C CB . ILE B 2 5 ? 56.490 -2.612 5.475 1.00 58.26 ? 37 ILE B CB 1 ATOM 3412 C CG1 . ILE B 2 5 ? 56.004 -2.357 6.906 1.00 54.46 ? 37 ILE B CG1 1 ATOM 3413 C CG2 . ILE B 2 5 ? 56.828 -4.086 5.297 1.00 56.88 ? 37 ILE B CG2 1 ATOM 3414 C CD1 . ILE B 2 5 ? 56.999 -2.703 7.995 1.00 53.37 ? 37 ILE B CD1 1 ATOM 3415 N N . GLY B 2 6 ? 59.509 -2.548 3.696 1.00 62.21 ? 38 GLY B N 1 ATOM 3416 C CA . GLY B 2 6 ? 60.089 -3.104 2.464 1.00 61.28 ? 38 GLY B CA 1 ATOM 3417 C C . GLY B 2 6 ? 59.686 -4.558 2.301 1.00 56.25 ? 38 GLY B C 1 ATOM 3418 O O . GLY B 2 6 ? 59.438 -5.228 3.295 1.00 57.85 ? 38 GLY B O 1 ATOM 3419 N N . GLN B 2 7 ? 59.618 -5.053 1.068 1.00 50.46 ? 39 GLN B N 1 ATOM 3420 C CA . GLN B 2 7 ? 59.126 -6.413 0.824 1.00 48.52 ? 39 GLN B CA 1 ATOM 3421 C C . GLN B 2 7 ? 59.845 -7.098 -0.329 1.00 49.78 ? 39 GLN B C 1 ATOM 3422 O O . GLN B 2 7 ? 60.145 -6.466 -1.333 1.00 59.11 ? 39 GLN B O 1 ATOM 3423 C CB . GLN B 2 7 ? 57.612 -6.391 0.545 1.00 45.16 ? 39 GLN B CB 1 ATOM 3424 C CG . GLN B 2 7 ? 56.743 -6.104 1.772 1.00 42.48 ? 39 GLN B CG 1 ATOM 3425 C CD . GLN B 2 7 ? 55.375 -6.759 1.716 1.00 38.79 ? 39 GLN B CD 1 ATOM 3426 O OE1 . GLN B 2 7 ? 54.844 -7.001 0.650 1.00 39.24 ? 39 GLN B OE1 1 ATOM 3427 N NE2 . GLN B 2 7 ? 54.805 -7.043 2.867 1.00 37.04 ? 39 GLN B NE2 1 ATOM 3428 N N . PHE B 2 8 ? 60.133 -8.388 -0.209 1.00 46.91 ? 40 PHE B N 1 ATOM 3429 C CA . PHE B 2 8 ? 60.612 -9.110 -1.385 1.00 42.68 ? 40 PHE B CA 1 ATOM 3430 C C . PHE B 2 8 ? 60.254 -10.572 -1.358 1.00 37.91 ? 40 PHE B C 1 ATOM 3431 O O . PHE B 2 8 ? 59.977 -11.136 -0.315 1.00 36.67 ? 40 PHE B O 1 ATOM 3432 C CB . PHE B 2 8 ? 62.112 -8.886 -1.629 1.00 42.36 ? 40 PHE B CB 1 ATOM 3433 C CG . PHE B 2 8 ? 63.003 -9.353 -0.518 1.00 42.41 ? 40 PHE B CG 1 ATOM 3434 C CD1 . PHE B 2 8 ? 63.431 -8.468 0.460 1.00 42.01 ? 40 PHE B CD1 1 ATOM 3435 C CD2 . PHE B 2 8 ? 63.458 -10.668 -0.481 1.00 42.43 ? 40 PHE B CD2 1 ATOM 3436 C CE1 . PHE B 2 8 ? 64.278 -8.890 1.472 1.00 43.35 ? 40 PHE B CE1 1 ATOM 3437 C CE2 . PHE B 2 8 ? 64.299 -11.105 0.535 1.00 44.03 ? 40 PHE B CE2 1 ATOM 3438 C CZ . PHE B 2 8 ? 64.711 -10.213 1.517 1.00 44.76 ? 40 PHE B CZ 1 ATOM 3439 N N . TRP B 2 9 ? 60.219 -11.159 -2.543 1.00 36.17 ? 41 TRP B N 1 ATOM 3440 C CA . TRP B 2 9 ? 59.822 -12.542 -2.704 1.00 35.91 ? 41 TRP B CA 1 ATOM 3441 C C . TRP B 2 9 ? 61.055 -13.358 -2.799 1.00 35.79 ? 41 TRP B C 1 ATOM 3442 O O . TRP B 2 9 ? 62.097 -12.871 -3.290 1.00 36.58 ? 41 TRP B O 1 ATOM 3443 C CB . TRP B 2 9 ? 59.052 -12.752 -4.001 1.00 36.46 ? 41 TRP B CB 1 ATOM 3444 C CG . TRP B 2 9 ? 57.729 -12.145 -3.976 1.00 36.08 ? 41 TRP B CG 1 ATOM 3445 C CD1 . TRP B 2 9 ? 57.375 -10.905 -4.430 1.00 36.10 ? 41 TRP B CD1 1 ATOM 3446 C CD2 . TRP B 2 9 ? 56.560 -12.731 -3.446 1.00 34.32 ? 41 TRP B CD2 1 ATOM 3447 N NE1 . TRP B 2 9 ? 56.040 -10.689 -4.210 1.00 34.97 ? 41 TRP B NE1 1 ATOM 3448 C CE2 . TRP B 2 9 ? 55.513 -11.798 -3.612 1.00 33.89 ? 41 TRP B CE2 1 ATOM 3449 C CE3 . TRP B 2 9 ? 56.290 -13.956 -2.855 1.00 33.52 ? 41 TRP B CE3 1 ATOM 3450 C CZ2 . TRP B 2 9 ? 54.224 -12.053 -3.211 1.00 35.04 ? 41 TRP B CZ2 1 ATOM 3451 C CZ3 . TRP B 2 9 ? 55.007 -14.212 -2.449 1.00 35.80 ? 41 TRP B CZ3 1 ATOM 3452 C CH2 . TRP B 2 9 ? 53.982 -13.263 -2.625 1.00 36.19 ? 41 TRP B CH2 1 ATOM 3453 N N . HIS B 2 10 ? 60.926 -14.608 -2.360 1.00 32.55 ? 42 HIS B N 1 ATOM 3454 C CA . HIS B 2 10 ? 61.940 -15.623 -2.610 1.00 30.01 ? 42 HIS B CA 1 ATOM 3455 C C . HIS B 2 10 ? 61.201 -16.717 -3.307 1.00 26.81 ? 42 HIS B C 1 ATOM 3456 O O . HIS B 2 10 ? 60.162 -17.149 -2.832 1.00 25.88 ? 42 HIS B O 1 ATOM 3457 C CB . HIS B 2 10 ? 62.549 -16.145 -1.310 1.00 31.28 ? 42 HIS B CB 1 ATOM 3458 C CG . HIS B 2 10 ? 63.807 -16.938 -1.493 1.00 32.89 ? 42 HIS B CG 1 ATOM 3459 N ND1 . HIS B 2 10 ? 64.886 -16.824 -0.645 1.00 34.84 ? 42 HIS B ND1 1 ATOM 3460 C CD2 . HIS B 2 10 ? 64.162 -17.855 -2.422 1.00 34.49 ? 42 HIS B CD2 1 ATOM 3461 C CE1 . HIS B 2 10 ? 65.851 -17.635 -1.044 1.00 34.95 ? 42 HIS B CE1 1 ATOM 3462 N NE2 . HIS B 2 10 ? 65.438 -18.272 -2.120 1.00 33.76 ? 42 HIS B NE2 1 ATOM 3463 N N . VAL B 2 11 ? 61.710 -17.110 -4.469 1.00 25.47 ? 43 VAL B N 1 ATOM 3464 C CA . VAL B 2 11 ? 61.241 -18.300 -5.195 1.00 23.27 ? 43 VAL B CA 1 ATOM 3465 C C . VAL B 2 11 ? 62.463 -19.145 -5.396 1.00 23.28 ? 43 VAL B C 1 ATOM 3466 O O . VAL B 2 11 ? 63.523 -18.624 -5.775 1.00 23.20 ? 43 VAL B O 1 ATOM 3467 C CB . VAL B 2 11 ? 60.591 -17.969 -6.556 1.00 21.26 ? 43 VAL B CB 1 ATOM 3468 C CG1 . VAL B 2 11 ? 59.400 -17.074 -6.368 1.00 21.52 ? 43 VAL B CG1 1 ATOM 3469 C CG2 . VAL B 2 11 ? 61.556 -17.285 -7.489 1.00 21.21 ? 43 VAL B CG2 1 ATOM 3470 N N . THR B 2 12 ? 62.367 -20.436 -5.125 1.00 24.10 ? 44 THR B N 1 ATOM 3471 C CA . THR B 2 12 ? 63.498 -21.272 -5.473 1.00 26.17 ? 44 THR B CA 1 ATOM 3472 C C . THR B 2 12 ? 63.113 -22.609 -6.040 1.00 28.97 ? 44 THR B C 1 ATOM 3473 O O . THR B 2 12 ? 61.983 -23.072 -5.840 1.00 30.44 ? 44 THR B O 1 ATOM 3474 C CB . THR B 2 12 ? 64.459 -21.451 -4.298 1.00 25.66 ? 44 THR B CB 1 ATOM 3475 O OG1 . THR B 2 12 ? 65.694 -21.986 -4.799 1.00 26.77 ? 44 THR B OG1 1 ATOM 3476 C CG2 . THR B 2 12 ? 63.866 -22.344 -3.184 1.00 25.60 ? 44 THR B CG2 1 ATOM 3477 N N . ASP B 2 13 ? 64.067 -23.210 -6.757 1.00 31.36 ? 45 ASP B N 1 ATOM 3478 C CA . ASP B 2 13 ? 63.961 -24.592 -7.180 1.00 32.77 ? 45 ASP B CA 1 ATOM 3479 C C . ASP B 2 13 ? 62.637 -24.758 -7.864 1.00 34.16 ? 45 ASP B C 1 ATOM 3480 O O . ASP B 2 13 ? 61.701 -25.309 -7.300 1.00 37.17 ? 45 ASP B O 1 ATOM 3481 C CB . ASP B 2 13 ? 64.056 -25.520 -5.977 1.00 33.20 ? 45 ASP B CB 1 ATOM 3482 C CG . ASP B 2 13 ? 65.362 -25.380 -5.264 1.00 37.53 ? 45 ASP B CG 1 ATOM 3483 O OD1 . ASP B 2 13 ? 65.452 -24.614 -4.285 1.00 41.07 ? 45 ASP B OD1 1 ATOM 3484 O OD2 . ASP B 2 13 ? 66.329 -26.024 -5.694 1.00 42.65 -1 45 ASP B OD2 1 ATOM 3485 N N . LEU B 2 14 ? 62.544 -24.249 -9.075 1.00 33.52 ? 46 LEU B N 1 ATOM 3486 C CA . LEU B 2 14 ? 61.316 -24.351 -9.812 1.00 33.96 ? 46 LEU B CA 1 ATOM 3487 C C . LEU B 2 14 ? 61.246 -25.694 -10.472 1.00 34.10 ? 46 LEU B C 1 ATOM 3488 O O . LEU B 2 14 ? 60.165 -26.250 -10.639 1.00 35.67 ? 46 LEU B O 1 ATOM 3489 C CB . LEU B 2 14 ? 61.276 -23.269 -10.852 1.00 37.86 ? 46 LEU B CB 1 ATOM 3490 C CG . LEU B 2 14 ? 61.446 -21.890 -10.222 1.00 41.26 ? 46 LEU B CG 1 ATOM 3491 C CD1 . LEU B 2 14 ? 61.564 -20.851 -11.312 1.00 42.75 ? 46 LEU B CD1 1 ATOM 3492 C CD2 . LEU B 2 14 ? 60.279 -21.584 -9.288 1.00 41.41 ? 46 LEU B CD2 1 ATOM 3493 N N . HIS B 2 15 ? 62.414 -26.209 -10.857 1.00 34.17 ? 47 HIS B N 1 ATOM 3494 C CA . HIS B 2 15 ? 62.565 -27.573 -11.373 1.00 33.35 ? 47 HIS B CA 1 ATOM 3495 C C . HIS B 2 15 ? 61.414 -27.931 -12.314 1.00 36.37 ? 47 HIS B C 1 ATOM 3496 O O . HIS B 2 15 ? 60.547 -28.762 -11.977 1.00 36.24 ? 47 HIS B O 1 ATOM 3497 C CB . HIS B 2 15 ? 62.695 -28.589 -10.222 1.00 29.82 ? 47 HIS B CB 1 ATOM 3498 C CG . HIS B 2 15 ? 64.061 -28.642 -9.615 1.00 26.49 ? 47 HIS B CG 1 ATOM 3499 N ND1 . HIS B 2 15 ? 65.207 -28.678 -10.373 1.00 26.83 ? 47 HIS B ND1 1 ATOM 3500 C CD2 . HIS B 2 15 ? 64.470 -28.670 -8.331 1.00 24.77 ? 47 HIS B CD2 1 ATOM 3501 C CE1 . HIS B 2 15 ? 66.260 -28.720 -9.585 1.00 24.76 ? 47 HIS B CE1 1 ATOM 3502 N NE2 . HIS B 2 15 ? 65.838 -28.724 -8.340 1.00 23.87 ? 47 HIS B NE2 1 ATOM 3503 N N . LEU B 2 16 ? 61.409 -27.266 -13.477 1.00 36.67 ? 48 LEU B N 1 ATOM 3504 C CA . LEU B 2 16 ? 60.400 -27.501 -14.523 1.00 34.95 ? 48 LEU B CA 1 ATOM 3505 C C . LEU B 2 16 ? 60.628 -28.817 -15.258 1.00 31.55 ? 48 LEU B C 1 ATOM 3506 O O . LEU B 2 16 ? 61.732 -29.124 -15.684 1.00 28.36 ? 48 LEU B O 1 ATOM 3507 C CB . LEU B 2 16 ? 60.390 -26.366 -15.560 1.00 34.93 ? 48 LEU B CB 1 ATOM 3508 C CG . LEU B 2 16 ? 59.413 -26.582 -16.730 1.00 33.88 ? 48 LEU B CG 1 ATOM 3509 C CD1 . LEU B 2 16 ? 58.004 -26.156 -16.318 1.00 33.28 ? 48 LEU B CD1 1 ATOM 3510 C CD2 . LEU B 2 16 ? 59.898 -25.854 -17.982 1.00 34.00 ? 48 LEU B CD2 1 ATOM 3511 N N . ASP B 2 17 ? 59.543 -29.553 -15.426 1.00 31.12 ? 49 ASP B N 1 ATOM 3512 C CA . ASP B 2 17 ? 59.525 -30.761 -16.218 1.00 31.71 ? 49 ASP B CA 1 ATOM 3513 C C . ASP B 2 17 ? 58.644 -30.468 -17.437 1.00 30.69 ? 49 ASP B C 1 ATOM 3514 O O . ASP B 2 17 ? 57.410 -30.490 -17.300 1.00 27.60 ? 49 ASP B O 1 ATOM 3515 C CB . ASP B 2 17 ? 58.947 -31.920 -15.381 1.00 31.76 ? 49 ASP B CB 1 ATOM 3516 C CG . ASP B 2 17 ? 59.448 -33.283 -15.829 1.00 30.17 ? 49 ASP B CG 1 ATOM 3517 O OD1 . ASP B 2 17 ? 59.840 -33.438 -17.006 1.00 27.74 ? 49 ASP B OD1 1 ATOM 3518 O OD2 . ASP B 2 17 ? 59.420 -34.199 -14.986 1.00 28.38 -1 49 ASP B OD2 1 ATOM 3519 N N . PRO B 2 18 ? 59.279 -30.138 -18.610 1.00 31.46 ? 50 PRO B N 1 ATOM 3520 C CA . PRO B 2 18 ? 58.619 -29.964 -19.915 1.00 30.04 ? 50 PRO B CA 1 ATOM 3521 C C . PRO B 2 18 ? 57.784 -31.166 -20.327 1.00 29.49 ? 50 PRO B C 1 ATOM 3522 O O . PRO B 2 18 ? 56.789 -30.995 -21.013 1.00 30.32 ? 50 PRO B O 1 ATOM 3523 C CB . PRO B 2 18 ? 59.791 -29.791 -20.877 1.00 29.08 ? 50 PRO B CB 1 ATOM 3524 C CG . PRO B 2 18 ? 60.849 -29.138 -20.074 1.00 29.16 ? 50 PRO B CG 1 ATOM 3525 C CD . PRO B 2 18 ? 60.710 -29.764 -18.709 1.00 31.20 ? 50 PRO B CD 1 ATOM 3526 N N . THR B 2 19 ? 58.170 -32.355 -19.886 1.00 27.55 ? 51 THR B N 1 ATOM 3527 C CA . THR B 2 19 ? 57.425 -33.555 -20.158 1.00 28.27 ? 51 THR B CA 1 ATOM 3528 C C . THR B 2 19 ? 56.049 -33.698 -19.576 1.00 31.34 ? 51 THR B C 1 ATOM 3529 O O . THR B 2 19 ? 55.222 -34.414 -20.139 1.00 33.28 ? 51 THR B O 1 ATOM 3530 C CB . THR B 2 19 ? 58.124 -34.708 -19.505 1.00 28.64 ? 51 THR B CB 1 ATOM 3531 O OG1 . THR B 2 19 ? 59.497 -34.590 -19.824 1.00 28.95 ? 51 THR B OG1 1 ATOM 3532 C CG2 . THR B 2 19 ? 57.526 -36.086 -19.981 1.00 29.38 ? 51 THR B CG2 1 ATOM 3533 N N . TYR B 2 20 ? 55.825 -33.130 -18.399 1.00 34.01 ? 52 TYR B N 1 ATOM 3534 C CA . TYR B 2 20 ? 54.643 -33.494 -17.599 1.00 35.47 ? 52 TYR B CA 1 ATOM 3535 C C . TYR B 2 20 ? 53.399 -33.410 -18.433 1.00 34.57 ? 52 TYR B C 1 ATOM 3536 O O . TYR B 2 20 ? 53.234 -32.465 -19.175 1.00 31.68 ? 52 TYR B O 1 ATOM 3537 C CB . TYR B 2 20 ? 54.481 -32.571 -16.363 1.00 38.11 ? 52 TYR B CB 1 ATOM 3538 C CG . TYR B 2 20 ? 53.436 -33.035 -15.355 1.00 37.86 ? 52 TYR B CG 1 ATOM 3539 C CD1 . TYR B 2 20 ? 52.135 -32.574 -15.412 1.00 37.22 ? 52 TYR B CD1 1 ATOM 3540 C CD2 . TYR B 2 20 ? 53.762 -33.950 -14.356 1.00 40.76 ? 52 TYR B CD2 1 ATOM 3541 C CE1 . TYR B 2 20 ? 51.183 -33.000 -14.503 1.00 39.05 ? 52 TYR B CE1 1 ATOM 3542 C CE2 . TYR B 2 20 ? 52.815 -34.401 -13.447 1.00 40.76 ? 52 TYR B CE2 1 ATOM 3543 C CZ . TYR B 2 20 ? 51.522 -33.921 -13.527 1.00 39.84 ? 52 TYR B CZ 1 ATOM 3544 O OH . TYR B 2 20 ? 50.578 -34.346 -12.623 1.00 38.81 ? 52 TYR B OH 1 ATOM 3545 N N . HIS B 2 21 ? 52.537 -34.400 -18.316 1.00 38.84 ? 53 HIS B N 1 ATOM 3546 C CA . HIS B 2 21 ? 51.162 -34.258 -18.758 1.00 48.10 ? 53 HIS B CA 1 ATOM 3547 C C . HIS B 2 21 ? 50.359 -35.469 -18.318 1.00 46.98 ? 53 HIS B C 1 ATOM 3548 O O . HIS B 2 21 ? 50.869 -36.589 -18.252 1.00 43.30 ? 53 HIS B O 1 ATOM 3549 C CB . HIS B 2 21 ? 51.051 -34.074 -20.289 1.00 58.83 ? 53 HIS B CB 1 ATOM 3550 C CG . HIS B 2 21 ? 51.407 -35.297 -21.070 1.00 67.56 ? 53 HIS B CG 1 ATOM 3551 N ND1 . HIS B 2 21 ? 52.712 -35.690 -21.283 1.00 74.65 ? 53 HIS B ND1 1 ATOM 3552 C CD2 . HIS B 2 21 ? 50.629 -36.235 -21.658 1.00 72.71 ? 53 HIS B CD2 1 ATOM 3553 C CE1 . HIS B 2 21 ? 52.723 -36.813 -21.978 1.00 77.48 ? 53 HIS B CE1 1 ATOM 3554 N NE2 . HIS B 2 21 ? 51.472 -37.164 -22.218 1.00 79.27 ? 53 HIS B NE2 1 ATOM 3555 N N . ILE B 2 22 ? 49.086 -35.244 -18.027 1.00 49.35 ? 54 ILE B N 1 ATOM 3556 C CA . ILE B 2 22 ? 48.212 -36.341 -17.654 1.00 49.17 ? 54 ILE B CA 1 ATOM 3557 C C . ILE B 2 22 ? 48.022 -37.264 -18.839 1.00 49.60 ? 54 ILE B C 1 ATOM 3558 O O . ILE B 2 22 ? 47.781 -36.845 -19.982 1.00 44.24 ? 54 ILE B O 1 ATOM 3559 C CB . ILE B 2 22 ? 46.825 -35.886 -17.158 1.00 49.24 ? 54 ILE B CB 1 ATOM 3560 C CG1 . ILE B 2 22 ? 46.969 -34.866 -16.025 1.00 47.64 ? 54 ILE B CG1 1 ATOM 3561 C CG2 . ILE B 2 22 ? 46.006 -37.098 -16.703 1.00 50.86 ? 54 ILE B CG2 1 ATOM 3562 C CD1 . ILE B 2 22 ? 47.827 -35.346 -14.882 1.00 47.98 ? 54 ILE B CD1 1 ATOM 3563 N N . THR B 2 23 ? 48.169 -38.538 -18.527 1.00 53.19 ? 55 THR B N 1 ATOM 3564 C CA . THR B 2 23 ? 47.813 -39.604 -19.430 1.00 55.61 ? 55 THR B CA 1 ATOM 3565 C C . THR B 2 23 ? 47.519 -40.814 -18.524 1.00 55.88 ? 55 THR B C 1 ATOM 3566 O O . THR B 2 23 ? 47.848 -40.824 -17.314 1.00 50.87 ? 55 THR B O 1 ATOM 3567 C CB . THR B 2 23 ? 48.914 -39.849 -20.511 1.00 56.33 ? 55 THR B CB 1 ATOM 3568 O OG1 . THR B 2 23 ? 48.431 -40.728 -21.547 1.00 56.39 ? 55 THR B OG1 1 ATOM 3569 C CG2 . THR B 2 23 ? 50.188 -40.438 -19.889 1.00 58.17 ? 55 THR B CG2 1 ATOM 3570 N N . ASP B 2 24 ? 46.867 -41.807 -19.117 1.00 57.11 ? 56 ASP B N 1 ATOM 3571 C CA . ASP B 2 24 ? 46.389 -42.975 -18.386 1.00 58.91 ? 56 ASP B CA 1 ATOM 3572 C C . ASP B 2 24 ? 47.508 -43.926 -17.958 1.00 57.80 ? 56 ASP B C 1 ATOM 3573 O O . ASP B 2 24 ? 47.353 -44.660 -16.985 1.00 53.82 ? 56 ASP B O 1 ATOM 3574 C CB . ASP B 2 24 ? 45.329 -43.688 -19.221 1.00 58.77 ? 56 ASP B CB 1 ATOM 3575 C CG . ASP B 2 24 ? 44.090 -42.834 -19.396 1.00 61.00 ? 56 ASP B CG 1 ATOM 3576 O OD1 . ASP B 2 24 ? 43.423 -42.541 -18.379 1.00 58.22 ? 56 ASP B OD1 1 ATOM 3577 O OD2 . ASP B 2 24 ? 43.805 -42.420 -20.539 1.00 65.53 -1 56 ASP B OD2 1 ATOM 3578 N N . ASP B 2 25 ? 48.619 -43.905 -18.696 1.00 58.91 ? 57 ASP B N 1 ATOM 3579 C CA . ASP B 2 25 ? 49.848 -44.603 -18.318 1.00 56.61 ? 57 ASP B CA 1 ATOM 3580 C C . ASP B 2 25 ? 50.646 -43.678 -17.372 1.00 56.14 ? 57 ASP B C 1 ATOM 3581 O O . ASP B 2 25 ? 51.210 -42.632 -17.775 1.00 51.72 ? 57 ASP B O 1 ATOM 3582 C CB . ASP B 2 25 ? 50.645 -44.980 -19.582 1.00 57.19 ? 57 ASP B CB 1 ATOM 3583 C CG . ASP B 2 25 ? 51.709 -46.045 -19.336 1.00 56.91 ? 57 ASP B CG 1 ATOM 3584 O OD1 . ASP B 2 25 ? 51.878 -46.507 -18.182 1.00 52.57 ? 57 ASP B OD1 1 ATOM 3585 O OD2 . ASP B 2 25 ? 52.386 -46.415 -20.326 1.00 58.40 -1 57 ASP B OD2 1 ATOM 3586 N N . HIS B 2 26 ? 50.667 -44.075 -16.100 1.00 54.81 ? 58 HIS B N 1 ATOM 3587 C CA . HIS B 2 26 ? 51.273 -43.275 -15.037 1.00 52.72 ? 58 HIS B CA 1 ATOM 3588 C C . HIS B 2 26 ? 52.791 -43.364 -15.021 1.00 48.22 ? 58 HIS B C 1 ATOM 3589 O O . HIS B 2 26 ? 53.436 -42.552 -14.363 1.00 46.08 ? 58 HIS B O 1 ATOM 3590 C CB . HIS B 2 26 ? 50.666 -43.651 -13.672 1.00 51.89 ? 58 HIS B CB 1 ATOM 3591 C CG . HIS B 2 26 ? 49.342 -43.004 -13.408 1.00 50.31 ? 58 HIS B CG 1 ATOM 3592 N ND1 . HIS B 2 26 ? 48.646 -42.304 -14.376 1.00 49.55 ? 58 HIS B ND1 1 ATOM 3593 C CD2 . HIS B 2 26 ? 48.585 -42.953 -12.288 1.00 49.95 ? 58 HIS B CD2 1 ATOM 3594 C CE1 . HIS B 2 26 ? 47.520 -41.849 -13.861 1.00 50.79 ? 58 HIS B CE1 1 ATOM 3595 N NE2 . HIS B 2 26 ? 47.464 -42.221 -12.593 1.00 52.18 ? 58 HIS B NE2 1 ATOM 3596 N N . THR B 2 27 ? 53.349 -44.336 -15.749 1.00 46.00 ? 59 THR B N 1 ATOM 3597 C CA . THR B 2 27 ? 54.794 -44.383 -15.997 1.00 44.47 ? 59 THR B CA 1 ATOM 3598 C C . THR B 2 27 ? 55.175 -43.301 -17.008 1.00 43.58 ? 59 THR B C 1 ATOM 3599 O O . THR B 2 27 ? 56.353 -42.977 -17.129 1.00 44.07 ? 59 THR B O 1 ATOM 3600 C CB . THR B 2 27 ? 55.310 -45.752 -16.534 1.00 43.79 ? 59 THR B CB 1 ATOM 3601 O OG1 . THR B 2 27 ? 55.093 -45.849 -17.951 1.00 43.25 ? 59 THR B OG1 1 ATOM 3602 C CG2 . THR B 2 27 ? 54.668 -46.960 -15.801 1.00 43.76 ? 59 THR B CG2 1 ATOM 3603 N N . LYS B 2 28 ? 54.182 -42.740 -17.710 1.00 41.80 ? 60 LYS B N 1 ATOM 3604 C CA . LYS B 2 28 ? 54.423 -41.868 -18.851 1.00 40.69 ? 60 LYS B CA 1 ATOM 3605 C C . LYS B 2 28 ? 54.055 -40.401 -18.619 1.00 42.04 ? 60 LYS B C 1 ATOM 3606 O O . LYS B 2 28 ? 54.354 -39.530 -19.449 1.00 43.94 ? 60 LYS B O 1 ATOM 3607 C CB . LYS B 2 28 ? 53.690 -42.439 -20.071 1.00 40.24 ? 60 LYS B CB 1 ATOM 3608 C CG . LYS B 2 28 ? 54.198 -43.801 -20.528 1.00 39.78 ? 60 LYS B CG 1 ATOM 3609 C CD . LYS B 2 28 ? 55.674 -43.718 -20.871 1.00 42.60 ? 60 LYS B CD 1 ATOM 3610 C CE . LYS B 2 28 ? 56.321 -45.076 -21.006 1.00 44.71 ? 60 LYS B CE 1 ATOM 3611 N NZ . LYS B 2 28 ? 56.126 -45.545 -22.401 1.00 47.60 1 60 LYS B NZ 1 ATOM 3612 N N . VAL B 2 29 ? 53.449 -40.120 -17.471 1.00 41.62 ? 61 VAL B N 1 ATOM 3613 C CA . VAL B 2 29 ? 53.037 -38.751 -17.098 1.00 39.64 ? 61 VAL B CA 1 ATOM 3614 C C . VAL B 2 29 ? 54.167 -37.674 -17.072 1.00 40.05 ? 61 VAL B C 1 ATOM 3615 O O . VAL B 2 29 ? 53.932 -36.496 -17.360 1.00 44.27 ? 61 VAL B O 1 ATOM 3616 C CB . VAL B 2 29 ? 52.288 -38.815 -15.747 1.00 37.11 ? 61 VAL B CB 1 ATOM 3617 C CG1 . VAL B 2 29 ? 52.262 -37.474 -15.015 1.00 36.85 ? 61 VAL B CG1 1 ATOM 3618 C CG2 . VAL B 2 29 ? 50.897 -39.358 -15.980 1.00 37.38 ? 61 VAL B CG2 1 ATOM 3619 N N . CYS B 2 30 ? 55.383 -38.049 -16.728 1.00 36.15 ? 62 CYS B N 1 ATOM 3620 C CA . CYS B 2 30 ? 56.417 -37.052 -16.597 1.00 34.91 ? 62 CYS B CA 1 ATOM 3621 C C . CYS B 2 30 ? 57.695 -37.817 -16.478 1.00 34.47 ? 62 CYS B C 1 ATOM 3622 O O . CYS B 2 30 ? 57.732 -38.850 -15.788 1.00 36.14 ? 62 CYS B O 1 ATOM 3623 C CB . CYS B 2 30 ? 56.206 -36.247 -15.330 1.00 35.18 ? 62 CYS B CB 1 ATOM 3624 S SG . CYS B 2 30 ? 56.962 -37.017 -13.868 1.00 38.64 ? 62 CYS B SG 1 ATOM 3625 N N . ALA B 2 31 ? 58.747 -37.332 -17.125 1.00 31.56 ? 63 ALA B N 1 ATOM 3626 C CA . ALA B 2 31 ? 60.012 -38.054 -17.117 1.00 30.36 ? 63 ALA B CA 1 ATOM 3627 C C . ALA B 2 31 ? 60.731 -38.039 -15.748 1.00 29.38 ? 63 ALA B C 1 ATOM 3628 O O . ALA B 2 31 ? 61.526 -38.939 -15.473 1.00 29.85 ? 63 ALA B O 1 ATOM 3629 C CB . ALA B 2 31 ? 60.931 -37.515 -18.194 1.00 30.46 ? 63 ALA B CB 1 ATOM 3630 N N . SER B 2 32 ? 60.453 -37.053 -14.888 1.00 27.17 ? 64 SER B N 1 ATOM 3631 C CA . SER B 2 32 ? 61.229 -36.887 -13.653 1.00 25.21 ? 64 SER B CA 1 ATOM 3632 C C . SER B 2 32 ? 61.125 -38.102 -12.769 1.00 23.87 ? 64 SER B C 1 ATOM 3633 O O . SER B 2 32 ? 62.091 -38.455 -12.097 1.00 22.71 ? 64 SER B O 1 ATOM 3634 C CB . SER B 2 32 ? 60.805 -35.636 -12.898 1.00 25.52 ? 64 SER B CB 1 ATOM 3635 O OG . SER B 2 32 ? 59.450 -35.326 -13.161 1.00 25.67 ? 64 SER B OG 1 ATOM 3636 N N . SER B 2 33 ? 59.973 -38.773 -12.827 1.00 23.90 ? 65 SER B N 1 ATOM 3637 C CA . SER B 2 33 ? 59.699 -39.969 -12.006 1.00 23.38 ? 65 SER B CA 1 ATOM 3638 C C . SER B 2 33 ? 60.551 -41.140 -12.414 1.00 22.45 ? 65 SER B C 1 ATOM 3639 O O . SER B 2 33 ? 60.507 -42.203 -11.763 1.00 21.45 ? 65 SER B O 1 ATOM 3640 C CB . SER B 2 33 ? 58.264 -40.421 -12.155 1.00 22.87 ? 65 SER B CB 1 ATOM 3641 O OG . SER B 2 33 ? 58.264 -41.465 -13.111 1.00 23.34 ? 65 SER B OG 1 ATOM 3642 N N . LYS B 2 34 ? 61.250 -40.956 -13.530 1.00 22.25 ? 66 LYS B N 1 ATOM 3643 C CA . LYS B 2 34 ? 62.182 -41.935 -14.070 1.00 24.19 ? 66 LYS B CA 1 ATOM 3644 C C . LYS B 2 34 ? 61.525 -43.335 -14.258 1.00 23.68 ? 66 LYS B C 1 ATOM 3645 O O . LYS B 2 34 ? 62.103 -44.376 -13.984 1.00 23.12 ? 66 LYS B O 1 ATOM 3646 C CB . LYS B 2 34 ? 63.463 -41.987 -13.207 1.00 25.21 ? 66 LYS B CB 1 ATOM 3647 C CG . LYS B 2 34 ? 64.202 -40.664 -13.084 1.00 26.30 ? 66 LYS B CG 1 ATOM 3648 C CD . LYS B 2 34 ? 65.025 -40.590 -11.804 1.00 28.59 ? 66 LYS B CD 1 ATOM 3649 C CE . LYS B 2 34 ? 65.495 -39.168 -11.461 1.00 31.08 ? 66 LYS B CE 1 ATOM 3650 N NZ . LYS B 2 34 ? 64.532 -38.416 -10.584 1.00 32.01 1 66 LYS B NZ 1 ATOM 3651 N N . GLY B 2 35 ? 60.307 -43.354 -14.743 1.00 23.64 ? 67 GLY B N 1 ATOM 3652 C CA . GLY B 2 35 ? 59.700 -44.610 -15.023 1.00 25.03 ? 67 GLY B CA 1 ATOM 3653 C C . GLY B 2 35 ? 58.796 -45.056 -13.919 1.00 26.84 ? 67 GLY B C 1 ATOM 3654 O O . GLY B 2 35 ? 58.038 -46.002 -14.106 1.00 28.58 ? 67 GLY B O 1 ATOM 3655 N N . ALA B 2 36 ? 58.829 -44.387 -12.775 1.00 29.32 ? 68 ALA B N 1 ATOM 3656 C CA . ALA B 2 36 ? 57.905 -44.763 -11.696 1.00 32.64 ? 68 ALA B CA 1 ATOM 3657 C C . ALA B 2 36 ? 56.433 -44.383 -12.023 1.00 33.74 ? 68 ALA B C 1 ATOM 3658 O O . ALA B 2 36 ? 56.202 -43.378 -12.669 1.00 33.03 ? 68 ALA B O 1 ATOM 3659 C CB . ALA B 2 36 ? 58.363 -44.153 -10.379 1.00 32.34 ? 68 ALA B CB 1 ATOM 3660 N N . ASN B 2 37 ? 55.458 -45.211 -11.624 1.00 36.63 ? 69 ASN B N 1 ATOM 3661 C CA . ASN B 2 37 ? 54.033 -44.827 -11.676 1.00 37.62 ? 69 ASN B CA 1 ATOM 3662 C C . ASN B 2 37 ? 53.886 -43.580 -10.815 1.00 38.12 ? 69 ASN B C 1 ATOM 3663 O O . ASN B 2 37 ? 54.202 -43.610 -9.615 1.00 37.70 ? 69 ASN B O 1 ATOM 3664 C CB . ASN B 2 37 ? 53.077 -45.948 -11.160 1.00 38.35 ? 69 ASN B CB 1 ATOM 3665 C CG . ASN B 2 37 ? 52.474 -46.813 -12.283 1.00 39.55 ? 69 ASN B CG 1 ATOM 3666 O OD1 . ASN B 2 37 ? 52.464 -46.418 -13.453 1.00 41.42 ? 69 ASN B OD1 1 ATOM 3667 N ND2 . ASN B 2 37 ? 51.947 -47.999 -11.918 1.00 39.20 ? 69 ASN B ND2 1 ATOM 3668 N N . ALA B 2 38 ? 53.460 -42.478 -11.434 1.00 38.85 ? 70 ALA B N 1 ATOM 3669 C CA . ALA B 2 38 ? 53.224 -41.220 -10.717 1.00 39.08 ? 70 ALA B CA 1 ATOM 3670 C C . ALA B 2 38 ? 52.103 -41.457 -9.718 1.00 38.23 ? 70 ALA B C 1 ATOM 3671 O O . ALA B 2 38 ? 51.117 -42.112 -10.057 1.00 37.84 ? 70 ALA B O 1 ATOM 3672 C CB . ALA B 2 38 ? 52.853 -40.121 -11.691 1.00 39.18 ? 70 ALA B CB 1 ATOM 3673 N N . SER B 2 39 ? 52.258 -40.944 -8.497 1.00 38.17 ? 71 SER B N 1 ATOM 3674 C CA . SER B 2 39 ? 51.432 -41.402 -7.359 1.00 38.89 ? 71 SER B CA 1 ATOM 3675 C C . SER B 2 39 ? 49.922 -41.190 -7.556 1.00 38.31 ? 71 SER B C 1 ATOM 3676 O O . SER B 2 39 ? 49.120 -42.113 -7.424 1.00 35.87 ? 71 SER B O 1 ATOM 3677 C CB . SER B 2 39 ? 51.878 -40.742 -6.045 1.00 37.50 ? 71 SER B CB 1 ATOM 3678 O OG . SER B 2 39 ? 51.044 -41.178 -4.984 1.00 34.75 ? 71 SER B OG 1 ATOM 3679 N N . ASN B 2 40 ? 49.554 -39.953 -7.853 1.00 38.77 ? 72 ASN B N 1 ATOM 3680 C CA . ASN B 2 40 ? 48.166 -39.578 -8.024 1.00 37.88 ? 72 ASN B CA 1 ATOM 3681 C C . ASN B 2 40 ? 48.137 -38.227 -8.725 1.00 35.43 ? 72 ASN B C 1 ATOM 3682 O O . ASN B 2 40 ? 47.848 -37.206 -8.114 1.00 31.98 ? 72 ASN B O 1 ATOM 3683 C CB . ASN B 2 40 ? 47.461 -39.510 -6.679 1.00 38.80 ? 72 ASN B CB 1 ATOM 3684 C CG . ASN B 2 40 ? 46.019 -39.133 -6.827 1.00 41.38 ? 72 ASN B CG 1 ATOM 3685 O OD1 . ASN B 2 40 ? 45.471 -39.171 -7.936 1.00 40.96 ? 72 ASN B OD1 1 ATOM 3686 N ND2 . ASN B 2 40 ? 45.390 -38.747 -5.723 1.00 44.66 ? 72 ASN B ND2 1 ATOM 3687 N N . PRO B 2 41 ? 48.456 -38.229 -10.028 1.00 35.04 ? 73 PRO B N 1 ATOM 3688 C CA . PRO B 2 41 ? 48.815 -36.988 -10.705 1.00 33.73 ? 73 PRO B CA 1 ATOM 3689 C C . PRO B 2 41 ? 47.595 -36.135 -11.075 1.00 30.85 ? 73 PRO B C 1 ATOM 3690 O O . PRO B 2 41 ? 46.551 -36.691 -11.395 1.00 29.25 ? 73 PRO B O 1 ATOM 3691 C CB . PRO B 2 41 ? 49.567 -37.485 -11.961 1.00 32.81 ? 73 PRO B CB 1 ATOM 3692 C CG . PRO B 2 41 ? 49.038 -38.843 -12.224 1.00 32.75 ? 73 PRO B CG 1 ATOM 3693 C CD . PRO B 2 41 ? 48.408 -39.375 -10.960 1.00 33.60 ? 73 PRO B CD 1 ATOM 3694 N N . GLY B 2 42 ? 47.763 -34.809 -11.027 1.00 28.30 ? 74 GLY B N 1 ATOM 3695 C CA . GLY B 2 42 ? 46.749 -33.840 -11.441 1.00 26.93 ? 74 GLY B CA 1 ATOM 3696 C C . GLY B 2 42 ? 47.340 -32.695 -12.255 1.00 26.89 ? 74 GLY B C 1 ATOM 3697 O O . GLY B 2 42 ? 48.518 -32.717 -12.644 1.00 24.92 ? 74 GLY B O 1 ATOM 3698 N N . PRO B 2 43 ? 46.524 -31.673 -12.531 1.00 27.53 ? 75 PRO B N 1 ATOM 3699 C CA . PRO B 2 43 ? 47.028 -30.555 -13.351 1.00 29.07 ? 75 PRO B CA 1 ATOM 3700 C C . PRO B 2 43 ? 48.252 -29.817 -12.753 1.00 31.51 ? 75 PRO B C 1 ATOM 3701 O O . PRO B 2 43 ? 49.041 -29.240 -13.494 1.00 32.22 ? 75 PRO B O 1 ATOM 3702 C CB . PRO B 2 43 ? 45.811 -29.621 -13.489 1.00 27.55 ? 75 PRO B CB 1 ATOM 3703 C CG . PRO B 2 43 ? 44.787 -30.108 -12.512 1.00 26.84 ? 75 PRO B CG 1 ATOM 3704 C CD . PRO B 2 43 ? 45.113 -31.521 -12.140 1.00 26.26 ? 75 PRO B CD 1 ATOM 3705 N N . PHE B 2 44 ? 48.414 -29.858 -11.431 1.00 34.92 ? 76 PHE B N 1 ATOM 3706 C CA . PHE B 2 44 ? 49.471 -29.112 -10.729 1.00 36.83 ? 76 PHE B CA 1 ATOM 3707 C C . PHE B 2 44 ? 50.625 -29.946 -10.208 1.00 37.25 ? 76 PHE B C 1 ATOM 3708 O O . PHE B 2 44 ? 51.561 -29.420 -9.553 1.00 36.25 ? 76 PHE B O 1 ATOM 3709 C CB . PHE B 2 44 ? 48.853 -28.388 -9.570 1.00 38.33 ? 76 PHE B CB 1 ATOM 3710 C CG . PHE B 2 44 ? 47.705 -27.584 -9.974 1.00 38.75 ? 76 PHE B CG 1 ATOM 3711 C CD1 . PHE B 2 44 ? 47.913 -26.418 -10.670 1.00 39.68 ? 76 PHE B CD1 1 ATOM 3712 C CD2 . PHE B 2 44 ? 46.420 -28.021 -9.720 1.00 39.44 ? 76 PHE B CD2 1 ATOM 3713 C CE1 . PHE B 2 44 ? 46.845 -25.666 -11.086 1.00 42.71 ? 76 PHE B CE1 1 ATOM 3714 C CE2 . PHE B 2 44 ? 45.341 -27.281 -10.135 1.00 41.87 ? 76 PHE B CE2 1 ATOM 3715 C CZ . PHE B 2 44 ? 45.549 -26.096 -10.817 1.00 43.46 ? 76 PHE B CZ 1 ATOM 3716 N N . GLY B 2 45 ? 50.693 -31.193 -10.588 1.00 36.07 ? 77 GLY B N 1 ATOM 3717 C CA . GLY B 2 45 ? 51.859 -31.919 -10.207 1.00 35.91 ? 77 GLY B CA 1 ATOM 3718 C C . GLY B 2 45 ? 51.674 -33.218 -9.539 1.00 35.92 ? 77 GLY B C 1 ATOM 3719 O O . GLY B 2 45 ? 50.623 -33.783 -9.523 1.00 34.20 ? 77 GLY B O 1 ATOM 3720 N N . ASP B 2 46 ? 52.757 -33.672 -8.958 1.00 35.84 ? 78 ASP B N 1 ATOM 3721 C CA . ASP B 2 46 ? 52.740 -34.892 -8.256 1.00 34.86 ? 78 ASP B CA 1 ATOM 3722 C C . ASP B 2 46 ? 54.018 -34.997 -7.526 1.00 35.49 ? 78 ASP B C 1 ATOM 3723 O O . ASP B 2 46 ? 55.034 -34.636 -8.014 1.00 35.02 ? 78 ASP B O 1 ATOM 3724 C CB . ASP B 2 46 ? 52.669 -36.042 -9.257 1.00 33.31 ? 78 ASP B CB 1 ATOM 3725 C CG . ASP B 2 46 ? 52.254 -37.315 -8.645 1.00 34.57 ? 78 ASP B CG 1 ATOM 3726 O OD1 . ASP B 2 46 ? 51.380 -37.274 -7.800 1.00 34.93 ? 78 ASP B OD1 1 ATOM 3727 O OD2 . ASP B 2 46 ? 52.784 -38.363 -8.979 1.00 34.08 -1 78 ASP B OD2 1 ATOM 3728 N N . VAL B 2 47 ? 53.944 -35.480 -6.318 1.00 37.66 ? 79 VAL B N 1 ATOM 3729 C CA . VAL B 2 47 ? 55.152 -35.879 -5.573 1.00 39.25 ? 79 VAL B CA 1 ATOM 3730 C C . VAL B 2 47 ? 55.742 -36.873 -6.570 1.00 41.06 ? 79 VAL B C 1 ATOM 3731 O O . VAL B 2 47 ? 55.025 -37.255 -7.502 1.00 46.54 ? 79 VAL B O 1 ATOM 3732 C CB . VAL B 2 47 ? 54.799 -36.501 -4.175 1.00 39.13 ? 79 VAL B CB 1 ATOM 3733 C CG1 . VAL B 2 47 ? 54.062 -35.496 -3.295 1.00 39.25 ? 79 VAL B CG1 1 ATOM 3734 C CG2 . VAL B 2 47 ? 53.944 -37.767 -4.277 1.00 38.87 ? 79 VAL B CG2 1 ATOM 3735 N N . LEU B 2 48 ? 56.998 -37.290 -6.479 1.00 39.38 ? 80 LEU B N 1 ATOM 3736 C CA . LEU B 2 48 ? 57.527 -38.222 -7.553 1.00 40.83 ? 80 LEU B CA 1 ATOM 3737 C C . LEU B 2 48 ? 57.653 -37.663 -9.009 1.00 41.14 ? 80 LEU B C 1 ATOM 3738 O O . LEU B 2 48 ? 58.134 -38.368 -9.898 1.00 40.92 ? 80 LEU B O 1 ATOM 3739 C CB . LEU B 2 48 ? 56.637 -39.483 -7.688 1.00 36.52 ? 80 LEU B CB 1 ATOM 3740 C CG . LEU B 2 48 ? 57.141 -40.787 -7.120 1.00 33.51 ? 80 LEU B CG 1 ATOM 3741 C CD1 . LEU B 2 48 ? 57.440 -40.630 -5.652 1.00 32.41 ? 80 LEU B CD1 1 ATOM 3742 C CD2 . LEU B 2 48 ? 56.076 -41.836 -7.362 1.00 32.93 ? 80 LEU B CD2 1 ATOM 3743 N N . CYS B 2 49 ? 57.163 -36.444 -9.242 1.00 40.48 ? 81 CYS B N 1 ATOM 3744 C CA . CYS B 2 49 ? 57.247 -35.756 -10.527 1.00 39.19 ? 81 CYS B CA 1 ATOM 3745 C C . CYS B 2 49 ? 57.613 -34.311 -10.211 1.00 39.17 ? 81 CYS B C 1 ATOM 3746 O O . CYS B 2 49 ? 56.978 -33.660 -9.360 1.00 38.59 ? 81 CYS B O 1 ATOM 3747 C CB . CYS B 2 49 ? 55.903 -35.735 -11.303 1.00 39.51 ? 81 CYS B CB 1 ATOM 3748 S SG . CYS B 2 49 ? 55.483 -37.083 -12.453 1.00 36.71 ? 81 CYS B SG 1 ATOM 3749 N N . ASP B 2 50 ? 58.612 -33.802 -10.920 1.00 39.09 ? 82 ASP B N 1 ATOM 3750 C CA . ASP B 2 50 ? 58.930 -32.391 -10.871 1.00 39.22 ? 82 ASP B CA 1 ATOM 3751 C C . ASP B 2 50 ? 57.789 -31.474 -11.338 1.00 41.46 ? 82 ASP B C 1 ATOM 3752 O O . ASP B 2 50 ? 56.700 -31.931 -11.702 1.00 43.33 ? 82 ASP B O 1 ATOM 3753 C CB . ASP B 2 50 ? 60.135 -32.123 -11.742 1.00 38.55 ? 82 ASP B CB 1 ATOM 3754 C CG . ASP B 2 50 ? 61.380 -32.074 -10.943 1.00 40.89 ? 82 ASP B CG 1 ATOM 3755 O OD1 . ASP B 2 50 ? 61.433 -31.283 -9.976 1.00 41.72 ? 82 ASP B OD1 1 ATOM 3756 O OD2 . ASP B 2 50 ? 62.303 -32.844 -11.254 1.00 44.64 -1 82 ASP B OD2 1 ATOM 3757 N N . SER B 2 51 ? 58.029 -30.172 -11.279 1.00 42.71 ? 83 SER B N 1 ATOM 3758 C CA . SER B 2 51 ? 57.017 -29.192 -11.641 1.00 42.89 ? 83 SER B CA 1 ATOM 3759 C C . SER B 2 51 ? 56.473 -29.229 -13.083 1.00 44.65 ? 83 SER B C 1 ATOM 3760 O O . SER B 2 51 ? 57.234 -29.132 -14.058 1.00 42.28 ? 83 SER B O 1 ATOM 3761 C CB . SER B 2 51 ? 57.533 -27.785 -11.339 1.00 41.56 ? 83 SER B CB 1 ATOM 3762 O OG . SER B 2 51 ? 57.855 -27.625 -9.979 1.00 38.67 ? 83 SER B OG 1 ATOM 3763 N N . PRO B 2 52 ? 55.137 -29.358 -13.217 1.00 48.84 ? 84 PRO B N 1 ATOM 3764 C CA . PRO B 2 52 ? 54.526 -29.065 -14.506 1.00 49.10 ? 84 PRO B CA 1 ATOM 3765 C C . PRO B 2 52 ? 54.542 -27.585 -14.713 1.00 46.01 ? 84 PRO B C 1 ATOM 3766 O O . PRO B 2 52 ? 54.600 -26.850 -13.742 1.00 46.52 ? 84 PRO B O 1 ATOM 3767 C CB . PRO B 2 52 ? 53.079 -29.545 -14.342 1.00 50.80 ? 84 PRO B CB 1 ATOM 3768 C CG . PRO B 2 52 ? 52.826 -29.594 -12.879 1.00 50.72 ? 84 PRO B CG 1 ATOM 3769 C CD . PRO B 2 52 ? 54.150 -29.840 -12.226 1.00 50.61 ? 84 PRO B CD 1 ATOM 3770 N N . TYR B 2 53 ? 54.466 -27.143 -15.955 1.00 45.13 ? 85 TYR B N 1 ATOM 3771 C CA . TYR B 2 53 ? 54.447 -25.716 -16.224 1.00 45.31 ? 85 TYR B CA 1 ATOM 3772 C C . TYR B 2 53 ? 53.331 -24.953 -15.466 1.00 44.15 ? 85 TYR B C 1 ATOM 3773 O O . TYR B 2 53 ? 53.537 -23.810 -15.074 1.00 40.50 ? 85 TYR B O 1 ATOM 3774 C CB . TYR B 2 53 ? 54.355 -25.465 -17.727 1.00 46.13 ? 85 TYR B CB 1 ATOM 3775 C CG . TYR B 2 53 ? 54.553 -24.013 -18.095 1.00 49.00 ? 85 TYR B CG 1 ATOM 3776 C CD1 . TYR B 2 53 ? 55.736 -23.346 -17.755 1.00 49.30 ? 85 TYR B CD1 1 ATOM 3777 C CD2 . TYR B 2 53 ? 53.551 -23.290 -18.763 1.00 48.32 ? 85 TYR B CD2 1 ATOM 3778 C CE1 . TYR B 2 53 ? 55.917 -22.006 -18.076 1.00 50.15 ? 85 TYR B CE1 1 ATOM 3779 C CE2 . TYR B 2 53 ? 53.720 -21.950 -19.076 1.00 49.71 ? 85 TYR B CE2 1 ATOM 3780 C CZ . TYR B 2 53 ? 54.912 -21.318 -18.736 1.00 49.89 ? 85 TYR B CZ 1 ATOM 3781 O OH . TYR B 2 53 ? 55.115 -20.004 -19.048 1.00 49.51 ? 85 TYR B OH 1 ATOM 3782 N N . GLN B 2 54 ? 52.174 -25.577 -15.233 1.00 47.12 ? 86 GLN B N 1 ATOM 3783 C CA . GLN B 2 54 ? 51.031 -24.868 -14.611 1.00 51.59 ? 86 GLN B CA 1 ATOM 3784 C C . GLN B 2 54 ? 51.069 -24.778 -13.076 1.00 50.73 ? 86 GLN B C 1 ATOM 3785 O O . GLN B 2 54 ? 50.310 -24.012 -12.455 1.00 47.23 ? 86 GLN B O 1 ATOM 3786 C CB . GLN B 2 54 ? 49.719 -25.502 -15.029 1.00 55.67 ? 86 GLN B CB 1 ATOM 3787 C CG . GLN B 2 54 ? 48.573 -24.527 -14.879 1.00 62.88 ? 86 GLN B CG 1 ATOM 3788 C CD . GLN B 2 54 ? 47.248 -25.112 -15.298 1.00 75.98 ? 86 GLN B CD 1 ATOM 3789 O OE1 . GLN B 2 54 ? 46.314 -24.374 -15.632 1.00 89.95 ? 86 GLN B OE1 1 ATOM 3790 N NE2 . GLN B 2 54 ? 47.148 -26.444 -15.283 1.00 80.60 ? 86 GLN B NE2 1 ATOM 3791 N N . LEU B 2 55 ? 51.925 -25.608 -12.481 1.00 49.94 ? 87 LEU B N 1 ATOM 3792 C CA . LEU B 2 55 ? 52.319 -25.485 -11.082 1.00 45.67 ? 87 LEU B CA 1 ATOM 3793 C C . LEU B 2 55 ? 53.128 -24.204 -10.941 1.00 44.44 ? 87 LEU B C 1 ATOM 3794 O O . LEU B 2 55 ? 52.681 -23.251 -10.301 1.00 46.73 ? 87 LEU B O 1 ATOM 3795 C CB . LEU B 2 55 ? 53.160 -26.694 -10.671 1.00 43.92 ? 87 LEU B CB 1 ATOM 3796 C CG . LEU B 2 55 ? 53.902 -26.643 -9.353 1.00 42.27 ? 87 LEU B CG 1 ATOM 3797 C CD1 . LEU B 2 55 ? 52.894 -26.452 -8.242 1.00 44.93 ? 87 LEU B CD1 1 ATOM 3798 C CD2 . LEU B 2 55 ? 54.666 -27.925 -9.162 1.00 40.68 ? 87 LEU B CD2 1 ATOM 3799 N N . ILE B 2 56 ? 54.295 -24.175 -11.583 1.00 41.20 ? 88 ILE B N 1 ATOM 3800 C CA . ILE B 2 56 ? 55.142 -23.000 -11.570 1.00 42.08 ? 88 ILE B CA 1 ATOM 3801 C C . ILE B 2 56 ? 54.403 -21.751 -12.054 1.00 44.02 ? 88 ILE B C 1 ATOM 3802 O O . ILE B 2 56 ? 54.686 -20.654 -11.560 1.00 51.85 ? 88 ILE B O 1 ATOM 3803 C CB . ILE B 2 56 ? 56.364 -23.176 -12.468 1.00 44.94 ? 88 ILE B CB 1 ATOM 3804 C CG1 . ILE B 2 56 ? 57.218 -24.364 -11.991 1.00 48.18 ? 88 ILE B CG1 1 ATOM 3805 C CG2 . ILE B 2 56 ? 57.181 -21.883 -12.486 1.00 45.54 ? 88 ILE B CG2 1 ATOM 3806 C CD1 . ILE B 2 56 ? 58.306 -24.800 -12.972 1.00 49.43 ? 88 ILE B CD1 1 ATOM 3807 N N . LEU B 2 57 ? 53.488 -21.904 -13.024 1.00 40.60 ? 89 LEU B N 1 ATOM 3808 C CA . LEU B 2 57 ? 52.745 -20.771 -13.575 1.00 36.36 ? 89 LEU B CA 1 ATOM 3809 C C . LEU B 2 57 ? 51.833 -20.228 -12.514 1.00 35.70 ? 89 LEU B C 1 ATOM 3810 O O . LEU B 2 57 ? 51.775 -19.045 -12.332 1.00 37.90 ? 89 LEU B O 1 ATOM 3811 C CB . LEU B 2 57 ? 51.928 -21.162 -14.807 1.00 36.33 ? 89 LEU B CB 1 ATOM 3812 C CG . LEU B 2 57 ? 51.531 -20.084 -15.835 1.00 37.40 ? 89 LEU B CG 1 ATOM 3813 C CD1 . LEU B 2 57 ? 52.700 -19.287 -16.414 1.00 37.01 ? 89 LEU B CD1 1 ATOM 3814 C CD2 . LEU B 2 57 ? 50.799 -20.744 -16.993 1.00 38.89 ? 89 LEU B CD2 1 ATOM 3815 N N . SER B 2 58 ? 51.140 -21.097 -11.792 1.00 35.68 ? 90 SER B N 1 ATOM 3816 C CA . SER B 2 58 ? 50.228 -20.681 -10.718 1.00 34.37 ? 90 SER B CA 1 ATOM 3817 C C . SER B 2 58 ? 50.899 -19.997 -9.531 1.00 35.81 ? 90 SER B C 1 ATOM 3818 O O . SER B 2 58 ? 50.245 -19.237 -8.803 1.00 39.24 ? 90 SER B O 1 ATOM 3819 C CB . SER B 2 58 ? 49.540 -21.900 -10.167 1.00 32.33 ? 90 SER B CB 1 ATOM 3820 O OG . SER B 2 58 ? 50.509 -22.781 -9.661 1.00 31.05 ? 90 SER B OG 1 ATOM 3821 N N . ALA B 2 59 ? 52.171 -20.315 -9.305 1.00 33.92 ? 91 ALA B N 1 ATOM 3822 C CA . ALA B 2 59 ? 52.931 -19.723 -8.225 1.00 33.78 ? 91 ALA B CA 1 ATOM 3823 C C . ALA B 2 59 ? 53.163 -18.272 -8.495 1.00 34.48 ? 91 ALA B C 1 ATOM 3824 O O . ALA B 2 59 ? 53.023 -17.455 -7.616 1.00 35.04 ? 91 ALA B O 1 ATOM 3825 C CB . ALA B 2 59 ? 54.262 -20.420 -8.068 1.00 33.69 ? 91 ALA B CB 1 ATOM 3826 N N . PHE B 2 60 ? 53.554 -17.958 -9.716 1.00 38.97 ? 92 PHE B N 1 ATOM 3827 C CA . PHE B 2 60 ? 53.795 -16.556 -10.126 1.00 44.25 ? 92 PHE B CA 1 ATOM 3828 C C . PHE B 2 60 ? 52.506 -15.698 -10.283 1.00 46.23 ? 92 PHE B C 1 ATOM 3829 O O . PHE B 2 60 ? 52.421 -14.613 -9.708 1.00 44.92 ? 92 PHE B O 1 ATOM 3830 C CB . PHE B 2 60 ? 54.590 -16.519 -11.436 1.00 43.02 ? 92 PHE B CB 1 ATOM 3831 C CG . PHE B 2 60 ? 56.017 -16.948 -11.297 1.00 41.92 ? 92 PHE B CG 1 ATOM 3832 C CD1 . PHE B 2 60 ? 56.874 -16.267 -10.429 1.00 44.32 ? 92 PHE B CD1 1 ATOM 3833 C CD2 . PHE B 2 60 ? 56.512 -17.992 -12.059 1.00 39.15 ? 92 PHE B CD2 1 ATOM 3834 C CE1 . PHE B 2 60 ? 58.201 -16.623 -10.317 1.00 45.07 ? 92 PHE B CE1 1 ATOM 3835 C CE2 . PHE B 2 60 ? 57.826 -18.357 -11.953 1.00 40.96 ? 92 PHE B CE2 1 ATOM 3836 C CZ . PHE B 2 60 ? 58.679 -17.672 -11.087 1.00 44.82 ? 92 PHE B CZ 1 ATOM 3837 N N . ASP B 2 61 ? 51.532 -16.182 -11.069 1.00 47.23 ? 93 ASP B N 1 ATOM 3838 C CA . ASP B 2 61 ? 50.188 -15.594 -11.141 1.00 48.33 ? 93 ASP B CA 1 ATOM 3839 C C . ASP B 2 61 ? 49.651 -15.307 -9.744 1.00 53.54 ? 93 ASP B C 1 ATOM 3840 O O . ASP B 2 61 ? 48.913 -14.330 -9.577 1.00 63.66 ? 93 ASP B O 1 ATOM 3841 C CB . ASP B 2 61 ? 49.158 -16.521 -11.820 1.00 47.17 ? 93 ASP B CB 1 ATOM 3842 C CG . ASP B 2 61 ? 49.460 -16.794 -13.261 1.00 46.15 ? 93 ASP B CG 1 ATOM 3843 O OD1 . ASP B 2 61 ? 50.147 -15.958 -13.895 1.00 45.72 ? 93 ASP B OD1 1 ATOM 3844 O OD2 . ASP B 2 61 ? 49.010 -17.861 -13.744 1.00 44.02 -1 93 ASP B OD2 1 ATOM 3845 N N . PHE B 2 62 ? 49.949 -16.174 -8.760 1.00 50.59 ? 94 PHE B N 1 ATOM 3846 C CA . PHE B 2 62 ? 49.557 -15.875 -7.388 1.00 45.11 ? 94 PHE B CA 1 ATOM 3847 C C . PHE B 2 62 ? 50.364 -14.659 -6.937 1.00 42.13 ? 94 PHE B C 1 ATOM 3848 O O . PHE B 2 62 ? 49.803 -13.733 -6.378 1.00 45.56 ? 94 PHE B O 1 ATOM 3849 C CB . PHE B 2 62 ? 49.736 -17.047 -6.417 1.00 43.85 ? 94 PHE B CB 1 ATOM 3850 C CG . PHE B 2 62 ? 49.683 -16.621 -4.976 1.00 45.29 ? 94 PHE B CG 1 ATOM 3851 C CD1 . PHE B 2 62 ? 48.467 -16.532 -4.304 1.00 46.95 ? 94 PHE B CD1 1 ATOM 3852 C CD2 . PHE B 2 62 ? 50.838 -16.231 -4.307 1.00 46.60 ? 94 PHE B CD2 1 ATOM 3853 C CE1 . PHE B 2 62 ? 48.407 -16.112 -2.975 1.00 47.18 ? 94 PHE B CE1 1 ATOM 3854 C CE2 . PHE B 2 62 ? 50.787 -15.789 -2.985 1.00 49.17 ? 94 PHE B CE2 1 ATOM 3855 C CZ . PHE B 2 62 ? 49.569 -15.736 -2.313 1.00 48.19 ? 94 PHE B CZ 1 ATOM 3856 N N . ILE B 2 63 ? 51.662 -14.630 -7.197 1.00 37.67 ? 95 ILE B N 1 ATOM 3857 C CA . ILE B 2 63 ? 52.440 -13.502 -6.749 1.00 39.27 ? 95 ILE B CA 1 ATOM 3858 C C . ILE B 2 63 ? 51.870 -12.215 -7.336 1.00 43.41 ? 95 ILE B C 1 ATOM 3859 O O . ILE B 2 63 ? 51.729 -11.229 -6.629 1.00 45.88 ? 95 ILE B O 1 ATOM 3860 C CB . ILE B 2 63 ? 53.950 -13.667 -7.042 1.00 40.44 ? 95 ILE B CB 1 ATOM 3861 C CG1 . ILE B 2 63 ? 54.583 -14.627 -5.998 1.00 40.29 ? 95 ILE B CG1 1 ATOM 3862 C CG2 . ILE B 2 63 ? 54.647 -12.306 -7.007 1.00 41.93 ? 95 ILE B CG2 1 ATOM 3863 C CD1 . ILE B 2 63 ? 56.046 -15.014 -6.165 1.00 37.03 ? 95 ILE B CD1 1 ATOM 3864 N N . LYS B 2 64 ? 51.513 -12.238 -8.617 1.00 50.56 ? 96 LYS B N 1 ATOM 3865 C CA . LYS B 2 64 ? 50.993 -11.050 -9.335 1.00 53.05 ? 96 LYS B CA 1 ATOM 3866 C C . LYS B 2 64 ? 49.682 -10.606 -8.705 1.00 49.75 ? 96 LYS B C 1 ATOM 3867 O O . LYS B 2 64 ? 49.562 -9.476 -8.281 1.00 48.28 ? 96 LYS B O 1 ATOM 3868 C CB . LYS B 2 64 ? 50.791 -11.377 -10.831 1.00 56.48 ? 96 LYS B CB 1 ATOM 3869 C CG . LYS B 2 64 ? 50.727 -10.213 -11.816 1.00 58.85 ? 96 LYS B CG 1 ATOM 3870 C CD . LYS B 2 64 ? 50.711 -10.766 -13.241 1.00 61.01 ? 96 LYS B CD 1 ATOM 3871 C CE . LYS B 2 64 ? 50.300 -9.736 -14.275 1.00 63.09 ? 96 LYS B CE 1 ATOM 3872 N NZ . LYS B 2 64 ? 48.872 -9.913 -14.658 1.00 62.73 1 96 LYS B NZ 1 ATOM 3873 N N . ASN B 2 65 ? 48.732 -11.528 -8.604 1.00 51.16 ? 97 ASN B N 1 ATOM 3874 C CA . ASN B 2 65 ? 47.403 -11.264 -8.041 1.00 54.40 ? 97 ASN B CA 1 ATOM 3875 C C . ASN B 2 65 ? 47.379 -11.300 -6.513 1.00 54.72 ? 97 ASN B C 1 ATOM 3876 O O . ASN B 2 65 ? 46.304 -11.417 -5.931 1.00 57.27 ? 97 ASN B O 1 ATOM 3877 C CB . ASN B 2 65 ? 46.379 -12.322 -8.514 1.00 56.47 ? 97 ASN B CB 1 ATOM 3878 C CG . ASN B 2 65 ? 46.203 -12.385 -10.026 1.00 56.31 ? 97 ASN B CG 1 ATOM 3879 O OD1 . ASN B 2 65 ? 45.238 -12.981 -10.498 1.00 59.28 ? 97 ASN B OD1 1 ATOM 3880 N ND2 . ASN B 2 65 ? 47.130 -11.808 -10.788 1.00 56.64 ? 97 ASN B ND2 1 ATOM 3881 N N . SER B 2 66 ? 48.541 -11.216 -5.862 1.00 54.82 ? 98 SER B N 1 ATOM 3882 C CA . SER B 2 66 ? 48.627 -11.402 -4.405 1.00 52.71 ? 98 SER B CA 1 ATOM 3883 C C . SER B 2 66 ? 48.070 -10.238 -3.610 1.00 52.47 ? 98 SER B C 1 ATOM 3884 O O . SER B 2 66 ? 47.602 -10.430 -2.498 1.00 54.68 ? 98 SER B O 1 ATOM 3885 C CB . SER B 2 66 ? 50.077 -11.620 -3.958 1.00 51.60 ? 98 SER B CB 1 ATOM 3886 O OG . SER B 2 66 ? 50.815 -10.408 -3.977 1.00 50.93 ? 98 SER B OG 1 ATOM 3887 N N . GLY B 2 67 ? 48.142 -9.033 -4.165 1.00 53.70 ? 99 GLY B N 1 ATOM 3888 C CA . GLY B 2 67 ? 47.840 -7.828 -3.399 1.00 56.39 ? 99 GLY B CA 1 ATOM 3889 C C . GLY B 2 67 ? 48.986 -7.470 -2.458 1.00 56.12 ? 99 GLY B C 1 ATOM 3890 O O . GLY B 2 67 ? 48.763 -6.804 -1.440 1.00 58.06 ? 99 GLY B O 1 ATOM 3891 N N . GLN B 2 68 ? 50.196 -7.946 -2.789 1.00 56.14 ? 100 GLN B N 1 ATOM 3892 C CA . GLN B 2 68 ? 51.450 -7.574 -2.115 1.00 53.04 ? 100 GLN B CA 1 ATOM 3893 C C . GLN B 2 68 ? 52.266 -6.827 -3.147 1.00 54.53 ? 100 GLN B C 1 ATOM 3894 O O . GLN B 2 68 ? 52.274 -7.217 -4.312 1.00 52.54 ? 100 GLN B O 1 ATOM 3895 C CB . GLN B 2 68 ? 52.263 -8.805 -1.643 1.00 49.56 ? 100 GLN B CB 1 ATOM 3896 C CG . GLN B 2 68 ? 51.641 -9.670 -0.531 1.00 46.46 ? 100 GLN B CG 1 ATOM 3897 C CD . GLN B 2 68 ? 51.828 -9.124 0.905 1.00 44.26 ? 100 GLN B CD 1 ATOM 3898 O OE1 . GLN B 2 68 ? 52.484 -8.104 1.138 1.00 41.83 ? 100 GLN B OE1 1 ATOM 3899 N NE2 . GLN B 2 68 ? 51.248 -9.819 1.871 1.00 41.67 ? 100 GLN B NE2 1 ATOM 3900 N N . GLU B 2 69 ? 52.934 -5.757 -2.730 1.00 59.82 ? 101 GLU B N 1 ATOM 3901 C CA . GLU B 2 69 ? 53.923 -5.094 -3.576 1.00 68.19 ? 101 GLU B CA 1 ATOM 3902 C C . GLU B 2 69 ? 55.322 -5.616 -3.195 1.00 66.44 ? 101 GLU B C 1 ATOM 3903 O O . GLU B 2 69 ? 55.469 -6.345 -2.208 1.00 69.95 ? 101 GLU B O 1 ATOM 3904 C CB . GLU B 2 69 ? 53.802 -3.559 -3.466 1.00 76.39 ? 101 GLU B CB 1 ATOM 3905 C CG . GLU B 2 69 ? 54.741 -2.858 -2.478 1.00 86.15 ? 101 GLU B CG 1 ATOM 3906 C CD . GLU B 2 69 ? 54.607 -3.343 -1.039 1.00 90.83 ? 101 GLU B CD 1 ATOM 3907 O OE1 . GLU B 2 69 ? 53.576 -3.966 -0.708 1.00 95.12 ? 101 GLU B OE1 1 ATOM 3908 O OE2 . GLU B 2 69 ? 55.540 -3.100 -0.235 1.00 92.46 -1 101 GLU B OE2 1 ATOM 3909 N N . ALA B 2 70 ? 56.336 -5.285 -3.989 1.00 60.29 ? 102 ALA B N 1 ATOM 3910 C CA . ALA B 2 70 ? 57.713 -5.610 -3.614 1.00 58.09 ? 102 ALA B CA 1 ATOM 3911 C C . ALA B 2 70 ? 58.740 -4.747 -4.382 1.00 56.84 ? 102 ALA B C 1 ATOM 3912 O O . ALA B 2 70 ? 58.504 -4.314 -5.508 1.00 60.86 ? 102 ALA B O 1 ATOM 3913 C CB . ALA B 2 70 ? 57.993 -7.119 -3.770 1.00 53.13 ? 102 ALA B CB 1 ATOM 3914 N N . SER B 2 71 ? 59.865 -4.468 -3.734 1.00 54.00 ? 103 SER B N 1 ATOM 3915 C CA . SER B 2 71 ? 60.995 -3.826 -4.379 1.00 49.70 ? 103 SER B CA 1 ATOM 3916 C C . SER B 2 71 ? 61.686 -4.807 -5.268 1.00 47.37 ? 103 SER B C 1 ATOM 3917 O O . SER B 2 71 ? 62.133 -4.447 -6.349 1.00 45.95 ? 103 SER B O 1 ATOM 3918 C CB . SER B 2 71 ? 61.987 -3.339 -3.346 1.00 49.08 ? 103 SER B CB 1 ATOM 3919 O OG . SER B 2 71 ? 61.418 -2.249 -2.658 1.00 51.12 ? 103 SER B OG 1 ATOM 3920 N N . PHE B 2 72 ? 61.774 -6.054 -4.810 1.00 46.12 ? 104 PHE B N 1 ATOM 3921 C CA . PHE B 2 72 ? 62.396 -7.101 -5.621 1.00 44.67 ? 104 PHE B CA 1 ATOM 3922 C C . PHE B 2 72 ? 61.836 -8.544 -5.436 1.00 41.23 ? 104 PHE B C 1 ATOM 3923 O O . PHE B 2 72 ? 60.764 -8.750 -4.851 1.00 38.43 ? 104 PHE B O 1 ATOM 3924 C CB . PHE B 2 72 ? 63.939 -7.009 -5.493 1.00 45.05 ? 104 PHE B CB 1 ATOM 3925 C CG . PHE B 2 72 ? 64.475 -7.134 -4.074 1.00 47.04 ? 104 PHE B CG 1 ATOM 3926 C CD1 . PHE B 2 72 ? 64.401 -6.067 -3.174 1.00 47.08 ? 104 PHE B CD1 1 ATOM 3927 C CD2 . PHE B 2 72 ? 65.110 -8.308 -3.656 1.00 45.54 ? 104 PHE B CD2 1 ATOM 3928 C CE1 . PHE B 2 72 ? 64.921 -6.188 -1.889 1.00 45.53 ? 104 PHE B CE1 1 ATOM 3929 C CE2 . PHE B 2 72 ? 65.624 -8.430 -2.371 1.00 44.02 ? 104 PHE B CE2 1 ATOM 3930 C CZ . PHE B 2 72 ? 65.532 -7.368 -1.490 1.00 44.24 ? 104 PHE B CZ 1 ATOM 3931 N N . MET B 2 73 ? 62.537 -9.500 -6.056 1.00 39.43 ? 105 MET B N 1 ATOM 3932 C CA . MET B 2 73 ? 62.304 -10.942 -5.951 1.00 37.43 ? 105 MET B CA 1 ATOM 3933 C C . MET B 2 73 ? 63.676 -11.559 -6.087 1.00 35.44 ? 105 MET B C 1 ATOM 3934 O O . MET B 2 73 ? 64.486 -11.069 -6.881 1.00 33.92 ? 105 MET B O 1 ATOM 3935 C CB . MET B 2 73 ? 61.435 -11.436 -7.102 1.00 38.64 ? 105 MET B CB 1 ATOM 3936 C CG . MET B 2 73 ? 61.274 -12.948 -7.234 1.00 39.51 ? 105 MET B CG 1 ATOM 3937 S SD . MET B 2 73 ? 60.115 -13.421 -8.567 1.00 44.15 ? 105 MET B SD 1 ATOM 3938 C CE . MET B 2 73 ? 58.514 -12.787 -8.041 1.00 41.16 ? 105 MET B CE 1 ATOM 3939 N N . ILE B 2 74 ? 63.941 -12.586 -5.280 1.00 33.27 ? 106 ILE B N 1 ATOM 3940 C CA A ILE B 2 74 ? 65.199 -13.328 -5.260 0.50 33.25 ? 106 ILE B CA 1 ATOM 3941 C CA B ILE B 2 74 ? 65.220 -13.292 -5.364 0.50 32.14 ? 106 ILE B CA 1 ATOM 3942 C C . ILE B 2 74 ? 64.911 -14.677 -5.880 1.00 31.33 ? 106 ILE B C 1 ATOM 3943 O O . ILE B 2 74 ? 63.909 -15.259 -5.554 1.00 30.32 ? 106 ILE B O 1 ATOM 3944 C CB A ILE B 2 74 ? 65.643 -13.558 -3.791 0.50 35.06 ? 106 ILE B CB 1 ATOM 3945 C CB B ILE B 2 74 ? 66.044 -13.312 -4.034 0.50 32.36 ? 106 ILE B CB 1 ATOM 3946 C CG1 A ILE B 2 74 ? 66.202 -12.272 -3.177 0.50 35.36 ? 106 ILE B CG1 1 ATOM 3947 C CG1 B ILE B 2 74 ? 65.399 -14.168 -2.928 0.50 32.02 ? 106 ILE B CG1 1 ATOM 3948 C CG2 A ILE B 2 74 ? 66.665 -14.680 -3.673 0.50 35.44 ? 106 ILE B CG2 1 ATOM 3949 C CG2 B ILE B 2 74 ? 66.270 -11.899 -3.501 0.50 32.42 ? 106 ILE B CG2 1 ATOM 3950 C CD1 A ILE B 2 74 ? 67.195 -11.591 -4.075 0.50 35.79 ? 106 ILE B CD1 1 ATOM 3951 C CD1 B ILE B 2 74 ? 66.249 -14.257 -1.673 0.50 30.67 ? 106 ILE B CD1 1 ATOM 3952 N N . TRP B 2 75 ? 65.785 -15.185 -6.731 1.00 32.18 ? 107 TRP B N 1 ATOM 3953 C CA . TRP B 2 75 ? 65.561 -16.473 -7.386 1.00 34.89 ? 107 TRP B CA 1 ATOM 3954 C C . TRP B 2 75 ? 66.790 -17.375 -7.190 1.00 35.15 ? 107 TRP B C 1 ATOM 3955 O O . TRP B 2 75 ? 67.841 -17.123 -7.783 1.00 37.35 ? 107 TRP B O 1 ATOM 3956 C CB . TRP B 2 75 ? 65.277 -16.211 -8.872 1.00 37.46 ? 107 TRP B CB 1 ATOM 3957 C CG . TRP B 2 75 ? 65.058 -17.407 -9.700 1.00 42.27 ? 107 TRP B CG 1 ATOM 3958 C CD1 . TRP B 2 75 ? 64.804 -18.666 -9.260 1.00 46.93 ? 107 TRP B CD1 1 ATOM 3959 C CD2 . TRP B 2 75 ? 65.022 -17.462 -11.125 1.00 45.71 ? 107 TRP B CD2 1 ATOM 3960 N NE1 . TRP B 2 75 ? 64.634 -19.513 -10.322 1.00 50.25 ? 107 TRP B NE1 1 ATOM 3961 C CE2 . TRP B 2 75 ? 64.761 -18.799 -11.484 1.00 48.52 ? 107 TRP B CE2 1 ATOM 3962 C CE3 . TRP B 2 75 ? 65.182 -16.512 -12.136 1.00 50.29 ? 107 TRP B CE3 1 ATOM 3963 C CZ2 . TRP B 2 75 ? 64.658 -19.223 -12.828 1.00 49.72 ? 107 TRP B CZ2 1 ATOM 3964 C CZ3 . TRP B 2 75 ? 65.084 -16.930 -13.471 1.00 51.76 ? 107 TRP B CZ3 1 ATOM 3965 C CH2 . TRP B 2 75 ? 64.821 -18.281 -13.799 1.00 50.39 ? 107 TRP B CH2 1 ATOM 3966 N N . THR B 2 76 ? 66.694 -18.418 -6.363 1.00 33.25 ? 108 THR B N 1 ATOM 3967 C CA . THR B 2 76 ? 67.910 -19.212 -6.064 1.00 33.31 ? 108 THR B CA 1 ATOM 3968 C C . THR B 2 76 ? 68.060 -20.571 -6.850 1.00 34.81 ? 108 THR B C 1 ATOM 3969 O O . THR B 2 76 ? 68.154 -21.653 -6.234 1.00 35.18 ? 108 THR B O 1 ATOM 3970 C CB . THR B 2 76 ? 68.084 -19.418 -4.549 1.00 30.00 ? 108 THR B CB 1 ATOM 3971 O OG1 . THR B 2 76 ? 66.952 -20.118 -4.067 1.00 29.17 ? 108 THR B OG1 1 ATOM 3972 C CG2 . THR B 2 76 ? 68.202 -18.080 -3.814 1.00 28.78 ? 108 THR B CG2 1 ATOM 3973 N N . GLY B 2 77 ? 68.063 -20.486 -8.195 1.00 32.43 ? 109 GLY B N 1 ATOM 3974 C CA . GLY B 2 77 ? 68.529 -21.560 -9.074 1.00 30.45 ? 109 GLY B CA 1 ATOM 3975 C C . GLY B 2 77 ? 67.650 -22.788 -9.281 1.00 30.01 ? 109 GLY B C 1 ATOM 3976 O O . GLY B 2 77 ? 66.443 -22.769 -8.989 1.00 31.06 ? 109 GLY B O 1 ATOM 3977 N N . ASP B 2 78 ? 68.297 -23.853 -9.787 1.00 29.30 ? 110 ASP B N 1 ATOM 3978 C CA . ASP B 2 78 ? 67.700 -25.197 -10.086 1.00 29.45 ? 110 ASP B CA 1 ATOM 3979 C C . ASP B 2 78 ? 66.440 -25.157 -10.942 1.00 28.60 ? 110 ASP B C 1 ATOM 3980 O O . ASP B 2 78 ? 65.339 -25.284 -10.419 1.00 29.02 ? 110 ASP B O 1 ATOM 3981 C CB . ASP B 2 78 ? 67.402 -25.986 -8.793 1.00 29.19 ? 110 ASP B CB 1 ATOM 3982 C CG . ASP B 2 78 ? 68.581 -26.831 -8.312 1.00 28.28 ? 110 ASP B CG 1 ATOM 3983 O OD1 . ASP B 2 78 ? 69.702 -26.631 -8.798 1.00 29.81 ? 110 ASP B OD1 1 ATOM 3984 O OD2 . ASP B 2 78 ? 68.393 -27.669 -7.415 1.00 25.29 -1 110 ASP B OD2 1 ATOM 3985 N N . SER B 2 79 ? 66.605 -24.951 -12.246 1.00 27.78 ? 111 SER B N 1 ATOM 3986 C CA . SER B 2 79 ? 65.470 -24.901 -13.173 1.00 27.11 ? 111 SER B CA 1 ATOM 3987 C C . SER B 2 79 ? 65.211 -26.189 -13.998 1.00 26.43 ? 111 SER B C 1 ATOM 3988 O O . SER B 2 79 ? 64.043 -26.604 -14.078 1.00 27.48 ? 111 SER B O 1 ATOM 3989 C CB . SER B 2 79 ? 65.497 -23.619 -14.027 1.00 27.98 ? 111 SER B CB 1 ATOM 3990 O OG . SER B 2 79 ? 65.100 -22.465 -13.269 1.00 28.47 ? 111 SER B OG 1 ATOM 3991 N N A PRO B 2 80 ? 66.265 -26.823 -14.564 0.50 25.41 ? 112 PRO B N 1 ATOM 3992 N N B PRO B 2 80 ? 66.254 -26.817 -14.597 0.50 25.32 ? 112 PRO B N 1 ATOM 3993 C CA A PRO B 2 80 ? 66.104 -28.147 -15.147 0.50 25.87 ? 112 PRO B CA 1 ATOM 3994 C CA B PRO B 2 80 ? 65.917 -28.083 -15.232 0.50 25.92 ? 112 PRO B CA 1 ATOM 3995 C C A PRO B 2 80 ? 65.582 -29.172 -14.143 0.50 27.87 ? 112 PRO B C 1 ATOM 3996 C C B PRO B 2 80 ? 65.595 -29.158 -14.202 0.50 27.92 ? 112 PRO B C 1 ATOM 3997 O O A PRO B 2 80 ? 65.830 -29.047 -12.950 0.50 28.47 ? 112 PRO B O 1 ATOM 3998 O O B PRO B 2 80 ? 66.004 -29.057 -13.050 0.50 28.67 ? 112 PRO B O 1 ATOM 3999 C CB A PRO B 2 80 ? 67.522 -28.511 -15.548 0.50 24.72 ? 112 PRO B CB 1 ATOM 4000 C CB B PRO B 2 80 ? 67.175 -28.444 -16.000 0.50 24.82 ? 112 PRO B CB 1 ATOM 4001 C CG A PRO B 2 80 ? 68.119 -27.214 -15.888 0.50 24.94 ? 112 PRO B CG 1 ATOM 4002 C CG B PRO B 2 80 ? 68.246 -27.823 -15.233 0.50 24.47 ? 112 PRO B CG 1 ATOM 4003 C CD A PRO B 2 80 ? 67.624 -26.321 -14.800 0.50 24.90 ? 112 PRO B CD 1 ATOM 4004 C CD B PRO B 2 80 ? 67.696 -26.553 -14.675 0.50 24.71 ? 112 PRO B CD 1 ATOM 4005 N N . PRO B 2 81 ? 64.885 -30.202 -14.627 1.00 29.86 ? 113 PRO B N 1 ATOM 4006 C CA . PRO B 2 81 ? 64.349 -31.237 -13.741 1.00 31.16 ? 113 PRO B CA 1 ATOM 4007 C C . PRO B 2 81 ? 65.370 -32.299 -13.270 1.00 32.00 ? 113 PRO B C 1 ATOM 4008 O O . PRO B 2 81 ? 66.568 -32.199 -13.553 1.00 31.57 ? 113 PRO B O 1 ATOM 4009 C CB . PRO B 2 81 ? 63.292 -31.909 -14.628 1.00 32.89 ? 113 PRO B CB 1 ATOM 4010 C CG . PRO B 2 81 ? 63.850 -31.786 -16.021 1.00 32.99 ? 113 PRO B CG 1 ATOM 4011 C CD . PRO B 2 81 ? 64.707 -30.541 -16.057 1.00 31.43 ? 113 PRO B CD 1 ATOM 4012 N N . HIS B 2 82 ? 64.871 -33.308 -12.555 1.00 32.30 ? 114 HIS B N 1 ATOM 4013 C CA . HIS B 2 82 ? 65.678 -34.425 -12.091 1.00 32.25 ? 114 HIS B CA 1 ATOM 4014 C C . HIS B 2 82 ? 65.442 -35.579 -13.023 1.00 31.53 ? 114 HIS B C 1 ATOM 4015 O O . HIS B 2 82 ? 64.561 -36.411 -12.816 1.00 29.64 ? 114 HIS B O 1 ATOM 4016 C CB . HIS B 2 82 ? 65.312 -34.821 -10.657 1.00 33.61 ? 114 HIS B CB 1 ATOM 4017 C CG . HIS B 2 82 ? 65.492 -33.715 -9.675 1.00 34.48 ? 114 HIS B CG 1 ATOM 4018 N ND1 . HIS B 2 82 ? 64.584 -32.686 -9.545 1.00 36.65 ? 114 HIS B ND1 1 ATOM 4019 C CD2 . HIS B 2 82 ? 66.493 -33.448 -8.804 1.00 35.58 ? 114 HIS B CD2 1 ATOM 4020 C CE1 . HIS B 2 82 ? 65.018 -31.832 -8.632 1.00 36.84 ? 114 HIS B CE1 1 ATOM 4021 N NE2 . HIS B 2 82 ? 66.175 -32.271 -8.167 1.00 35.98 ? 114 HIS B NE2 1 ATOM 4022 N N . VAL B 2 83 ? 66.229 -35.596 -14.079 1.00 32.75 ? 115 VAL B N 1 ATOM 4023 C CA . VAL B 2 83 ? 66.311 -36.752 -14.944 1.00 35.59 ? 115 VAL B CA 1 ATOM 4024 C C . VAL B 2 83 ? 67.796 -37.061 -15.200 1.00 37.26 ? 115 VAL B C 1 ATOM 4025 O O . VAL B 2 83 ? 68.663 -36.183 -15.018 1.00 35.35 ? 115 VAL B O 1 ATOM 4026 C CB . VAL B 2 83 ? 65.543 -36.528 -16.258 1.00 35.76 ? 115 VAL B CB 1 ATOM 4027 C CG1 . VAL B 2 83 ? 64.062 -36.298 -15.991 1.00 34.09 ? 115 VAL B CG1 1 ATOM 4028 C CG2 . VAL B 2 83 ? 66.135 -35.353 -17.016 1.00 37.23 ? 115 VAL B CG2 1 ATOM 4029 N N . PRO B 2 84 ? 68.102 -38.313 -15.597 1.00 39.87 ? 116 PRO B N 1 ATOM 4030 C CA . PRO B 2 84 ? 69.514 -38.703 -15.773 1.00 41.01 ? 116 PRO B CA 1 ATOM 4031 C C . PRO B 2 84 ? 70.217 -37.888 -16.864 1.00 43.53 ? 116 PRO B C 1 ATOM 4032 O O . PRO B 2 84 ? 69.572 -37.504 -17.850 1.00 43.30 ? 116 PRO B O 1 ATOM 4033 C CB . PRO B 2 84 ? 69.432 -40.181 -16.159 1.00 40.47 ? 116 PRO B CB 1 ATOM 4034 C CG . PRO B 2 84 ? 68.072 -40.633 -15.716 1.00 40.50 ? 116 PRO B CG 1 ATOM 4035 C CD . PRO B 2 84 ? 67.178 -39.440 -15.827 1.00 39.26 ? 116 PRO B CD 1 ATOM 4036 N N . VAL B 2 85 ? 71.515 -37.626 -16.669 1.00 45.35 ? 117 VAL B N 1 ATOM 4037 C CA . VAL B 2 85 ? 72.308 -36.729 -17.537 1.00 45.75 ? 117 VAL B CA 1 ATOM 4038 C C . VAL B 2 85 ? 72.215 -37.026 -19.043 1.00 47.55 ? 117 VAL B C 1 ATOM 4039 O O . VAL B 2 85 ? 72.054 -36.090 -19.830 1.00 49.40 ? 117 VAL B O 1 ATOM 4040 C CB . VAL B 2 85 ? 73.798 -36.723 -17.134 1.00 46.50 ? 117 VAL B CB 1 ATOM 4041 C CG1 . VAL B 2 85 ? 74.659 -36.046 -18.203 1.00 47.06 ? 117 VAL B CG1 1 ATOM 4042 C CG2 . VAL B 2 85 ? 73.982 -36.056 -15.778 1.00 46.11 ? 117 VAL B CG2 1 ATOM 4043 N N . PRO B 2 86 ? 72.347 -38.313 -19.456 1.00 48.62 ? 118 PRO B N 1 ATOM 4044 C CA . PRO B 2 86 ? 72.133 -38.679 -20.874 1.00 47.73 ? 118 PRO B CA 1 ATOM 4045 C C . PRO B 2 86 ? 70.741 -38.369 -21.461 1.00 46.82 ? 118 PRO B C 1 ATOM 4046 O O . PRO B 2 86 ? 70.580 -38.418 -22.680 1.00 49.75 ? 118 PRO B O 1 ATOM 4047 C CB . PRO B 2 86 ? 72.385 -40.198 -20.900 1.00 47.53 ? 118 PRO B CB 1 ATOM 4048 C CG . PRO B 2 86 ? 72.584 -40.628 -19.477 1.00 46.98 ? 118 PRO B CG 1 ATOM 4049 C CD . PRO B 2 86 ? 73.002 -39.412 -18.719 1.00 48.23 ? 118 PRO B CD 1 ATOM 4050 N N . GLU B 2 87 ? 69.751 -38.088 -20.615 1.00 47.50 ? 119 GLU B N 1 ATOM 4051 C CA . GLU B 2 87 ? 68.422 -37.696 -21.083 1.00 47.36 ? 119 GLU B CA 1 ATOM 4052 C C . GLU B 2 87 ? 68.334 -36.198 -21.324 1.00 47.10 ? 119 GLU B C 1 ATOM 4053 O O . GLU B 2 87 ? 67.368 -35.747 -21.931 1.00 47.35 ? 119 GLU B O 1 ATOM 4054 C CB . GLU B 2 87 ? 67.340 -38.125 -20.088 1.00 48.90 ? 119 GLU B CB 1 ATOM 4055 C CG . GLU B 2 87 ? 66.099 -38.680 -20.772 1.00 53.30 ? 119 GLU B CG 1 ATOM 4056 C CD . GLU B 2 87 ? 64.947 -39.006 -19.823 1.00 55.53 ? 119 GLU B CD 1 ATOM 4057 O OE1 . GLU B 2 87 ? 63.778 -38.839 -20.256 1.00 57.16 ? 119 GLU B OE1 1 ATOM 4058 O OE2 . GLU B 2 87 ? 65.195 -39.426 -18.665 1.00 51.08 -1 119 GLU B OE2 1 ATOM 4059 N N . LEU B 2 88 ? 69.341 -35.446 -20.859 1.00 46.43 ? 120 LEU B N 1 ATOM 4060 C CA . LEU B 2 88 ? 69.388 -33.972 -20.976 1.00 48.44 ? 120 LEU B CA 1 ATOM 4061 C C . LEU B 2 88 ? 70.607 -33.431 -21.740 1.00 45.19 ? 120 LEU B C 1 ATOM 4062 O O . LEU B 2 88 ? 71.517 -34.159 -22.073 1.00 45.98 ? 120 LEU B O 1 ATOM 4063 C CB . LEU B 2 88 ? 69.421 -33.325 -19.577 1.00 50.98 ? 120 LEU B CB 1 ATOM 4064 C CG . LEU B 2 88 ? 68.260 -33.439 -18.587 1.00 48.42 ? 120 LEU B CG 1 ATOM 4065 C CD1 . LEU B 2 88 ? 68.757 -32.819 -17.287 1.00 48.38 ? 120 LEU B CD1 1 ATOM 4066 C CD2 . LEU B 2 88 ? 66.966 -32.778 -19.072 1.00 47.57 ? 120 LEU B CD2 1 ATOM 4067 N N . SER B 2 89 ? 70.621 -32.126 -21.964 1.00 43.85 ? 121 SER B N 1 ATOM 4068 C CA . SER B 2 89 ? 71.786 -31.436 -22.488 1.00 44.77 ? 121 SER B CA 1 ATOM 4069 C C . SER B 2 89 ? 71.855 -29.936 -22.038 1.00 47.95 ? 121 SER B C 1 ATOM 4070 O O . SER B 2 89 ? 70.897 -29.365 -21.450 1.00 48.68 ? 121 SER B O 1 ATOM 4071 C CB . SER B 2 89 ? 71.774 -31.535 -24.010 1.00 43.54 ? 121 SER B CB 1 ATOM 4072 O OG . SER B 2 89 ? 70.925 -30.556 -24.587 1.00 40.32 ? 121 SER B OG 1 ATOM 4073 N N . THR B 2 90 ? 73.010 -29.325 -22.316 1.00 44.32 ? 122 THR B N 1 ATOM 4074 C CA . THR B 2 90 ? 73.221 -27.869 -22.243 1.00 40.83 ? 122 THR B CA 1 ATOM 4075 C C . THR B 2 90 ? 72.118 -27.065 -22.931 1.00 42.80 ? 122 THR B C 1 ATOM 4076 O O . THR B 2 90 ? 71.623 -26.046 -22.427 1.00 38.22 ? 122 THR B O 1 ATOM 4077 C CB . THR B 2 90 ? 74.548 -27.532 -22.950 1.00 38.12 ? 122 THR B CB 1 ATOM 4078 O OG1 . THR B 2 90 ? 75.621 -27.856 -22.077 1.00 34.15 ? 122 THR B OG1 1 ATOM 4079 C CG2 . THR B 2 90 ? 74.652 -26.080 -23.340 1.00 37.41 ? 122 THR B CG2 1 ATOM 4080 N N . ASP B 2 91 ? 71.776 -27.517 -24.124 1.00 47.32 ? 123 ASP B N 1 ATOM 4081 C CA . ASP B 2 91 ? 70.696 -26.895 -24.866 1.00 50.30 ? 123 ASP B CA 1 ATOM 4082 C C . ASP B 2 91 ? 69.369 -27.027 -24.124 1.00 48.40 ? 123 ASP B C 1 ATOM 4083 O O . ASP B 2 91 ? 68.655 -26.044 -24.014 1.00 48.16 ? 123 ASP B O 1 ATOM 4084 C CB . ASP B 2 91 ? 70.589 -27.445 -26.307 1.00 51.20 ? 123 ASP B CB 1 ATOM 4085 C CG . ASP B 2 91 ? 71.388 -26.618 -27.314 1.00 48.06 ? 123 ASP B CG 1 ATOM 4086 O OD1 . ASP B 2 91 ? 72.599 -26.365 -27.053 1.00 46.27 ? 123 ASP B OD1 1 ATOM 4087 O OD2 . ASP B 2 91 ? 70.781 -26.229 -28.345 1.00 44.08 -1 123 ASP B OD2 1 ATOM 4088 N N . THR B 2 92 ? 69.032 -28.205 -23.602 1.00 46.92 ? 124 THR B N 1 ATOM 4089 C CA . THR B 2 92 ? 67.764 -28.315 -22.890 1.00 51.10 ? 124 THR B CA 1 ATOM 4090 C C . THR B 2 92 ? 67.853 -27.458 -21.630 1.00 54.40 ? 124 THR B C 1 ATOM 4091 O O . THR B 2 92 ? 66.926 -26.673 -21.350 1.00 56.39 ? 124 THR B O 1 ATOM 4092 C CB . THR B 2 92 ? 67.365 -29.758 -22.528 1.00 52.48 ? 124 THR B CB 1 ATOM 4093 O OG1 . THR B 2 92 ? 68.033 -30.673 -23.393 1.00 54.46 ? 124 THR B OG1 1 ATOM 4094 C CG2 . THR B 2 92 ? 65.822 -29.956 -22.651 1.00 52.65 ? 124 THR B CG2 1 ATOM 4095 N N . VAL B 2 93 ? 68.966 -27.591 -20.895 1.00 52.03 ? 125 VAL B N 1 ATOM 4096 C CA . VAL B 2 93 ? 69.221 -26.792 -19.672 1.00 50.61 ? 125 VAL B CA 1 ATOM 4097 C C . VAL B 2 93 ? 68.877 -25.284 -19.869 1.00 48.42 ? 125 VAL B C 1 ATOM 4098 O O . VAL B 2 93 ? 68.101 -24.686 -19.088 1.00 44.77 ? 125 VAL B O 1 ATOM 4099 C CB . VAL B 2 93 ? 70.692 -27.012 -19.194 1.00 51.48 ? 125 VAL B CB 1 ATOM 4100 C CG1 . VAL B 2 93 ? 71.248 -25.838 -18.391 1.00 53.79 ? 125 VAL B CG1 1 ATOM 4101 C CG2 . VAL B 2 93 ? 70.793 -28.286 -18.382 1.00 49.48 ? 125 VAL B CG2 1 ATOM 4102 N N . ILE B 2 94 ? 69.435 -24.704 -20.934 1.00 43.02 ? 126 ILE B N 1 ATOM 4103 C CA . ILE B 2 94 ? 69.266 -23.291 -21.243 1.00 39.81 ? 126 ILE B CA 1 ATOM 4104 C C . ILE B 2 94 ? 67.879 -23.014 -21.822 1.00 38.34 ? 126 ILE B C 1 ATOM 4105 O O . ILE B 2 94 ? 67.282 -21.969 -21.593 1.00 33.93 ? 126 ILE B O 1 ATOM 4106 C CB . ILE B 2 94 ? 70.359 -22.831 -22.223 1.00 40.29 ? 126 ILE B CB 1 ATOM 4107 C CG1 . ILE B 2 94 ? 71.729 -22.943 -21.569 1.00 41.76 ? 126 ILE B CG1 1 ATOM 4108 C CG2 . ILE B 2 94 ? 70.155 -21.383 -22.656 1.00 40.04 ? 126 ILE B CG2 1 ATOM 4109 C CD1 . ILE B 2 94 ? 72.883 -22.783 -22.536 1.00 41.59 ? 126 ILE B CD1 1 ATOM 4110 N N . ASN B 2 95 ? 67.360 -23.947 -22.598 1.00 41.40 ? 127 ASN B N 1 ATOM 4111 C CA . ASN B 2 95 ? 65.979 -23.843 -23.004 1.00 44.01 ? 127 ASN B CA 1 ATOM 4112 C C . ASN B 2 95 ? 65.197 -23.593 -21.760 1.00 43.55 ? 127 ASN B C 1 ATOM 4113 O O . ASN B 2 95 ? 64.477 -22.604 -21.690 1.00 42.96 ? 127 ASN B O 1 ATOM 4114 C CB . ASN B 2 95 ? 65.469 -25.130 -23.638 1.00 49.29 ? 127 ASN B CB 1 ATOM 4115 C CG . ASN B 2 95 ? 66.102 -25.417 -24.984 1.00 53.29 ? 127 ASN B CG 1 ATOM 4116 O OD1 . ASN B 2 95 ? 66.432 -24.501 -25.766 1.00 56.88 ? 127 ASN B OD1 1 ATOM 4117 N ND2 . ASN B 2 95 ? 66.267 -26.707 -25.270 1.00 52.81 ? 127 ASN B ND2 1 ATOM 4118 N N . VAL B 2 96 ? 65.381 -24.476 -20.768 1.00 43.74 ? 128 VAL B N 1 ATOM 4119 C CA . VAL B 2 96 ? 64.650 -24.390 -19.495 1.00 42.94 ? 128 VAL B CA 1 ATOM 4120 C C . VAL B 2 96 ? 64.895 -23.105 -18.671 1.00 43.42 ? 128 VAL B C 1 ATOM 4121 O O . VAL B 2 96 ? 63.907 -22.516 -18.207 1.00 45.40 ? 128 VAL B O 1 ATOM 4122 C CB . VAL B 2 96 ? 64.846 -25.632 -18.617 1.00 39.75 ? 128 VAL B CB 1 ATOM 4123 C CG1 . VAL B 2 96 ? 64.264 -25.388 -17.232 1.00 39.91 ? 128 VAL B CG1 1 ATOM 4124 C CG2 . VAL B 2 96 ? 64.155 -26.821 -19.261 1.00 39.84 ? 128 VAL B CG2 1 ATOM 4125 N N . ILE B 2 97 ? 66.149 -22.659 -18.496 1.00 39.68 ? 129 ILE B N 1 ATOM 4126 C CA . ILE B 2 97 ? 66.409 -21.376 -17.789 1.00 39.13 ? 129 ILE B CA 1 ATOM 4127 C C . ILE B 2 97 ? 65.818 -20.142 -18.523 1.00 41.69 ? 129 ILE B C 1 ATOM 4128 O O . ILE B 2 97 ? 65.349 -19.167 -17.898 1.00 41.48 ? 129 ILE B O 1 ATOM 4129 C CB . ILE B 2 97 ? 67.912 -21.122 -17.558 1.00 38.21 ? 129 ILE B CB 1 ATOM 4130 C CG1 . ILE B 2 97 ? 68.520 -22.256 -16.757 1.00 39.89 ? 129 ILE B CG1 1 ATOM 4131 C CG2 . ILE B 2 97 ? 68.145 -19.801 -16.811 1.00 37.77 ? 129 ILE B CG2 1 ATOM 4132 C CD1 . ILE B 2 97 ? 70.005 -22.087 -16.480 1.00 42.04 ? 129 ILE B CD1 1 ATOM 4133 N N . THR B 2 98 ? 65.870 -20.174 -19.852 1.00 43.15 ? 130 THR B N 1 ATOM 4134 C CA . THR B 2 98 ? 65.321 -19.099 -20.669 1.00 41.60 ? 130 THR B CA 1 ATOM 4135 C C . THR B 2 98 ? 63.826 -19.024 -20.434 1.00 39.40 ? 130 THR B C 1 ATOM 4136 O O . THR B 2 98 ? 63.311 -17.936 -20.260 1.00 36.54 ? 130 THR B O 1 ATOM 4137 C CB . THR B 2 98 ? 65.578 -19.332 -22.183 1.00 42.18 ? 130 THR B CB 1 ATOM 4138 O OG1 . THR B 2 98 ? 66.985 -19.505 -22.427 1.00 40.45 ? 130 THR B OG1 1 ATOM 4139 C CG2 . THR B 2 98 ? 65.022 -18.164 -23.023 1.00 39.79 ? 130 THR B CG2 1 ATOM 4140 N N . ASN B 2 99 ? 63.150 -20.183 -20.423 1.00 39.54 ? 131 ASN B N 1 ATOM 4141 C CA . ASN B 2 99 ? 61.689 -20.240 -20.260 1.00 41.45 ? 131 ASN B CA 1 ATOM 4142 C C . ASN B 2 99 ? 61.286 -19.632 -18.929 1.00 42.35 ? 131 ASN B C 1 ATOM 4143 O O . ASN B 2 99 ? 60.426 -18.745 -18.893 1.00 42.32 ? 131 ASN B O 1 ATOM 4144 C CB . ASN B 2 99 ? 61.133 -21.672 -20.412 1.00 44.74 ? 131 ASN B CB 1 ATOM 4145 C CG . ASN B 2 99 ? 59.597 -21.710 -20.467 1.00 50.38 ? 131 ASN B CG 1 ATOM 4146 O OD1 . ASN B 2 99 ? 58.959 -21.383 -19.469 1.00 57.17 ? 131 ASN B OD1 1 ATOM 4147 N ND2 . ASN B 2 99 ? 58.990 -22.107 -21.632 1.00 52.32 ? 131 ASN B ND2 1 ATOM 4148 N N . MET B 2 100 ? 61.933 -20.086 -17.847 1.00 43.60 ? 132 MET B N 1 ATOM 4149 C CA . MET B 2 100 ? 61.792 -19.480 -16.491 1.00 41.68 ? 132 MET B CA 1 ATOM 4150 C C . MET B 2 100 ? 62.102 -17.979 -16.474 1.00 38.44 ? 132 MET B C 1 ATOM 4151 O O . MET B 2 100 ? 61.364 -17.208 -15.847 1.00 36.00 ? 132 MET B O 1 ATOM 4152 C CB . MET B 2 100 ? 62.671 -20.204 -15.435 1.00 40.63 ? 132 MET B CB 1 ATOM 4153 C CG . MET B 2 100 ? 62.242 -21.638 -15.138 1.00 40.06 ? 132 MET B CG 1 ATOM 4154 S SD . MET B 2 100 ? 60.537 -21.787 -14.525 1.00 40.66 ? 132 MET B SD 1 ATOM 4155 C CE . MET B 2 100 ? 59.550 -22.212 -15.955 1.00 38.57 ? 132 MET B CE 1 ATOM 4156 N N . THR B 2 101 ? 63.172 -17.577 -17.166 1.00 36.26 ? 133 THR B N 1 ATOM 4157 C CA . THR B 2 101 ? 63.567 -16.174 -17.195 1.00 38.16 ? 133 THR B CA 1 ATOM 4158 C C . THR B 2 101 ? 62.562 -15.263 -17.977 1.00 43.03 ? 133 THR B C 1 ATOM 4159 O O . THR B 2 101 ? 62.172 -14.180 -17.499 1.00 42.07 ? 133 THR B O 1 ATOM 4160 C CB . THR B 2 101 ? 65.005 -16.000 -17.709 1.00 36.89 ? 133 THR B CB 1 ATOM 4161 O OG1 . THR B 2 101 ? 65.918 -16.834 -16.969 1.00 34.85 ? 133 THR B OG1 1 ATOM 4162 C CG2 . THR B 2 101 ? 65.424 -14.557 -17.541 1.00 37.23 ? 133 THR B CG2 1 ATOM 4163 N N . THR B 2 102 ? 62.124 -15.701 -19.157 1.00 49.67 ? 134 THR B N 1 ATOM 4164 C CA . THR B 2 102 ? 61.070 -14.980 -19.896 1.00 51.49 ? 134 THR B CA 1 ATOM 4165 C C . THR B 2 102 ? 59.773 -14.879 -19.073 1.00 55.76 ? 134 THR B C 1 ATOM 4166 O O . THR B 2 102 ? 59.343 -13.773 -18.755 1.00 58.88 ? 134 THR B O 1 ATOM 4167 C CB . THR B 2 102 ? 60.788 -15.607 -21.277 1.00 49.04 ? 134 THR B CB 1 ATOM 4168 O OG1 . THR B 2 102 ? 62.029 -15.760 -21.972 1.00 45.55 ? 134 THR B OG1 1 ATOM 4169 C CG2 . THR B 2 102 ? 59.831 -14.718 -22.107 1.00 47.34 ? 134 THR B CG2 1 ATOM 4170 N N . THR B 2 103 ? 59.178 -16.016 -18.703 1.00 56.14 ? 135 THR B N 1 ATOM 4171 C CA . THR B 2 103 ? 57.978 -16.025 -17.835 1.00 57.90 ? 135 THR B CA 1 ATOM 4172 C C . THR B 2 103 ? 58.042 -15.043 -16.632 1.00 54.80 ? 135 THR B C 1 ATOM 4173 O O . THR B 2 103 ? 57.054 -14.318 -16.358 1.00 47.70 ? 135 THR B O 1 ATOM 4174 C CB . THR B 2 103 ? 57.679 -17.444 -17.293 1.00 60.09 ? 135 THR B CB 1 ATOM 4175 O OG1 . THR B 2 103 ? 57.863 -18.404 -18.337 1.00 65.29 ? 135 THR B OG1 1 ATOM 4176 C CG2 . THR B 2 103 ? 56.235 -17.551 -16.772 1.00 60.36 ? 135 THR B CG2 1 ATOM 4177 N N . ILE B 2 104 ? 59.178 -15.026 -15.918 1.00 53.11 ? 136 ILE B N 1 ATOM 4178 C CA . ILE B 2 104 ? 59.362 -14.065 -14.807 1.00 53.93 ? 136 ILE B CA 1 ATOM 4179 C C . ILE B 2 104 ? 59.363 -12.658 -15.413 1.00 53.64 ? 136 ILE B C 1 ATOM 4180 O O . ILE B 2 104 ? 58.653 -11.775 -14.903 1.00 54.99 ? 136 ILE B O 1 ATOM 4181 C CB . ILE B 2 104 ? 60.621 -14.327 -13.892 1.00 50.88 ? 136 ILE B CB 1 ATOM 4182 C CG1 . ILE B 2 104 ? 60.470 -15.648 -13.116 1.00 48.48 ? 136 ILE B CG1 1 ATOM 4183 C CG2 . ILE B 2 104 ? 60.850 -13.178 -12.892 1.00 47.35 ? 136 ILE B CG2 1 ATOM 4184 C CD1 . ILE B 2 104 ? 61.771 -16.208 -12.580 1.00 47.65 ? 136 ILE B CD1 1 ATOM 4185 N N . GLN B 2 105 ? 60.105 -12.469 -16.513 1.00 48.39 ? 137 GLN B N 1 ATOM 4186 C CA . GLN B 2 105 ? 60.214 -11.139 -17.140 1.00 49.26 ? 137 GLN B CA 1 ATOM 4187 C C . GLN B 2 105 ? 58.930 -10.584 -17.850 1.00 49.88 ? 137 GLN B C 1 ATOM 4188 O O . GLN B 2 105 ? 58.763 -9.367 -17.913 1.00 49.26 ? 137 GLN B O 1 ATOM 4189 C CB . GLN B 2 105 ? 61.421 -11.077 -18.088 1.00 48.10 ? 137 GLN B CB 1 ATOM 4190 C CG . GLN B 2 105 ? 62.777 -10.943 -17.411 1.00 47.53 ? 137 GLN B CG 1 ATOM 4191 C CD . GLN B 2 105 ? 63.947 -10.885 -18.401 1.00 49.29 ? 137 GLN B CD 1 ATOM 4192 O OE1 . GLN B 2 105 ? 63.756 -10.795 -19.603 1.00 43.54 ? 137 GLN B OE1 1 ATOM 4193 N NE2 . GLN B 2 105 ? 65.172 -10.946 -17.885 1.00 54.31 ? 137 GLN B NE2 1 ATOM 4194 N N . SER B 2 106 ? 58.052 -11.451 -18.377 1.00 53.16 ? 138 SER B N 1 ATOM 4195 C CA . SER B 2 106 ? 56.775 -11.027 -19.011 1.00 52.06 ? 138 SER B CA 1 ATOM 4196 C C . SER B 2 106 ? 55.651 -10.815 -18.018 1.00 54.76 ? 138 SER B C 1 ATOM 4197 O O . SER B 2 106 ? 54.908 -9.842 -18.148 1.00 61.77 ? 138 SER B O 1 ATOM 4198 C CB . SER B 2 106 ? 56.302 -12.029 -20.050 1.00 51.22 ? 138 SER B CB 1 ATOM 4199 O OG . SER B 2 106 ? 57.028 -11.839 -21.242 1.00 56.23 ? 138 SER B OG 1 ATOM 4200 N N . LEU B 2 107 ? 55.502 -11.731 -17.052 1.00 53.33 ? 139 LEU B N 1 ATOM 4201 C CA . LEU B 2 107 ? 54.544 -11.545 -15.956 1.00 49.13 ? 139 LEU B CA 1 ATOM 4202 C C . LEU B 2 107 ? 54.948 -10.387 -15.036 1.00 48.86 ? 139 LEU B C 1 ATOM 4203 O O . LEU B 2 107 ? 54.068 -9.691 -14.520 1.00 48.86 ? 139 LEU B O 1 ATOM 4204 C CB . LEU B 2 107 ? 54.364 -12.833 -15.151 1.00 48.16 ? 139 LEU B CB 1 ATOM 4205 C CG . LEU B 2 107 ? 53.358 -13.831 -15.742 1.00 51.09 ? 139 LEU B CG 1 ATOM 4206 C CD1 . LEU B 2 107 ? 53.521 -15.176 -15.056 1.00 52.03 ? 139 LEU B CD1 1 ATOM 4207 C CD2 . LEU B 2 107 ? 51.895 -13.378 -15.655 1.00 50.23 ? 139 LEU B CD2 1 ATOM 4208 N N . PHE B 2 108 ? 56.263 -10.168 -14.873 1.00 47.95 ? 140 PHE B N 1 ATOM 4209 C CA . PHE B 2 108 ? 56.821 -9.191 -13.916 1.00 48.23 ? 140 PHE B CA 1 ATOM 4210 C C . PHE B 2 108 ? 57.742 -8.149 -14.560 1.00 52.81 ? 140 PHE B C 1 ATOM 4211 O O . PHE B 2 108 ? 58.936 -8.057 -14.197 1.00 49.91 ? 140 PHE B O 1 ATOM 4212 C CB . PHE B 2 108 ? 57.584 -9.930 -12.801 1.00 47.77 ? 140 PHE B CB 1 ATOM 4213 C CG . PHE B 2 108 ? 56.737 -10.914 -12.056 1.00 43.97 ? 140 PHE B CG 1 ATOM 4214 C CD1 . PHE B 2 108 ? 55.672 -10.468 -11.278 1.00 40.94 ? 140 PHE B CD1 1 ATOM 4215 C CD2 . PHE B 2 108 ? 56.974 -12.267 -12.151 1.00 41.57 ? 140 PHE B CD2 1 ATOM 4216 C CE1 . PHE B 2 108 ? 54.864 -11.348 -10.608 1.00 39.22 ? 140 PHE B CE1 1 ATOM 4217 C CE2 . PHE B 2 108 ? 56.167 -13.155 -11.476 1.00 41.64 ? 140 PHE B CE2 1 ATOM 4218 C CZ . PHE B 2 108 ? 55.112 -12.698 -10.704 1.00 40.34 ? 140 PHE B CZ 1 ATOM 4219 N N . PRO B 2 109 ? 57.181 -7.330 -15.484 1.00 60.07 ? 141 PRO B N 1 ATOM 4220 C CA . PRO B 2 109 ? 57.972 -6.425 -16.352 1.00 63.05 ? 141 PRO B CA 1 ATOM 4221 C C . PRO B 2 109 ? 58.865 -5.428 -15.601 1.00 67.72 ? 141 PRO B C 1 ATOM 4222 O O . PRO B 2 109 ? 60.047 -5.254 -15.947 1.00 72.24 ? 141 PRO B O 1 ATOM 4223 C CB . PRO B 2 109 ? 56.902 -5.694 -17.185 1.00 60.01 ? 141 PRO B CB 1 ATOM 4224 C CG . PRO B 2 109 ? 55.608 -5.901 -16.468 1.00 57.63 ? 141 PRO B CG 1 ATOM 4225 C CD . PRO B 2 109 ? 55.727 -7.185 -15.714 1.00 57.65 ? 141 PRO B CD 1 ATOM 4226 N N . ASN B 2 110 ? 58.306 -4.812 -14.563 1.00 68.19 ? 142 ASN B N 1 ATOM 4227 C CA . ASN B 2 110 ? 58.990 -3.754 -13.828 1.00 68.32 ? 142 ASN B CA 1 ATOM 4228 C C . ASN B 2 110 ? 59.940 -4.299 -12.777 1.00 59.04 ? 142 ASN B C 1 ATOM 4229 O O . ASN B 2 110 ? 60.969 -3.700 -12.495 1.00 51.79 ? 142 ASN B O 1 ATOM 4230 C CB . ASN B 2 110 ? 57.955 -2.852 -13.163 1.00 76.65 ? 142 ASN B CB 1 ATOM 4231 C CG . ASN B 2 110 ? 56.801 -2.519 -14.090 1.00 82.21 ? 142 ASN B CG 1 ATOM 4232 O OD1 . ASN B 2 110 ? 55.627 -2.723 -13.746 1.00 84.49 ? 142 ASN B OD1 1 ATOM 4233 N ND2 . ASN B 2 110 ? 57.130 -2.034 -15.290 1.00 81.84 ? 142 ASN B ND2 1 ATOM 4234 N N . LEU B 2 111 ? 59.590 -5.455 -12.230 1.00 56.11 ? 143 LEU B N 1 ATOM 4235 C CA . LEU B 2 111 ? 60.234 -5.982 -11.039 1.00 54.83 ? 143 LEU B CA 1 ATOM 4236 C C . LEU B 2 111 ? 61.596 -6.623 -11.256 1.00 53.89 ? 143 LEU B C 1 ATOM 4237 O O . LEU B 2 111 ? 61.729 -7.580 -12.031 1.00 58.48 ? 143 LEU B O 1 ATOM 4238 C CB . LEU B 2 111 ? 59.343 -7.029 -10.416 1.00 54.37 ? 143 LEU B CB 1 ATOM 4239 C CG . LEU B 2 111 ? 59.908 -7.550 -9.111 1.00 53.50 ? 143 LEU B CG 1 ATOM 4240 C CD1 . LEU B 2 111 ? 59.717 -6.511 -8.019 1.00 52.15 ? 143 LEU B CD1 1 ATOM 4241 C CD2 . LEU B 2 111 ? 59.224 -8.862 -8.783 1.00 56.17 ? 143 LEU B CD2 1 ATOM 4242 N N . GLN B 2 112 ? 62.579 -6.121 -10.504 1.00 50.72 ? 144 GLN B N 1 ATOM 4243 C CA . GLN B 2 112 ? 63.960 -6.606 -10.554 1.00 46.68 ? 144 GLN B CA 1 ATOM 4244 C C . GLN B 2 112 ? 64.020 -7.931 -9.785 1.00 44.01 ? 144 GLN B C 1 ATOM 4245 O O . GLN B 2 112 ? 63.292 -8.160 -8.829 1.00 41.44 ? 144 GLN B O 1 ATOM 4246 C CB . GLN B 2 112 ? 64.938 -5.564 -9.968 1.00 42.80 ? 144 GLN B CB 1 ATOM 4247 C CG . GLN B 2 112 ? 66.426 -5.850 -10.185 1.00 40.45 ? 144 GLN B CG 1 ATOM 4248 C CD . GLN B 2 112 ? 67.360 -4.816 -9.522 1.00 39.40 ? 144 GLN B CD 1 ATOM 4249 O OE1 . GLN B 2 112 ? 66.914 -3.883 -8.846 1.00 36.41 ? 144 GLN B OE1 1 ATOM 4250 N NE2 . GLN B 2 112 ? 68.667 -4.987 -9.716 1.00 38.74 ? 144 GLN B NE2 1 ATOM 4251 N N . VAL B 2 113 ? 64.895 -8.802 -10.241 1.00 40.91 ? 145 VAL B N 1 ATOM 4252 C CA . VAL B 2 113 ? 64.963 -10.146 -9.765 1.00 39.05 ? 145 VAL B CA 1 ATOM 4253 C C . VAL B 2 113 ? 66.448 -10.453 -9.684 1.00 40.07 ? 145 VAL B C 1 ATOM 4254 O O . VAL B 2 113 ? 67.226 -9.969 -10.507 1.00 37.81 ? 145 VAL B O 1 ATOM 4255 C CB . VAL B 2 113 ? 64.269 -11.073 -10.774 1.00 38.99 ? 145 VAL B CB 1 ATOM 4256 C CG1 . VAL B 2 113 ? 64.383 -12.531 -10.363 1.00 38.32 ? 145 VAL B CG1 1 ATOM 4257 C CG2 . VAL B 2 113 ? 62.817 -10.643 -10.991 1.00 39.78 ? 145 VAL B CG2 1 ATOM 4258 N N . PHE B 2 114 ? 66.842 -11.231 -8.683 1.00 43.10 ? 146 PHE B N 1 ATOM 4259 C CA . PHE B 2 114 ? 68.250 -11.599 -8.482 1.00 45.30 ? 146 PHE B CA 1 ATOM 4260 C C . PHE B 2 114 ? 68.441 -13.117 -8.440 1.00 46.31 ? 146 PHE B C 1 ATOM 4261 O O . PHE B 2 114 ? 68.334 -13.747 -7.369 1.00 41.27 ? 146 PHE B O 1 ATOM 4262 C CB . PHE B 2 114 ? 68.815 -11.017 -7.192 1.00 45.81 ? 146 PHE B CB 1 ATOM 4263 C CG . PHE B 2 114 ? 68.708 -9.535 -7.088 1.00 43.82 ? 146 PHE B CG 1 ATOM 4264 C CD1 . PHE B 2 114 ? 67.486 -8.947 -6.822 1.00 43.45 ? 146 PHE B CD1 1 ATOM 4265 C CD2 . PHE B 2 114 ? 69.828 -8.745 -7.196 1.00 42.79 ? 146 PHE B CD2 1 ATOM 4266 C CE1 . PHE B 2 114 ? 67.381 -7.592 -6.687 1.00 43.72 ? 146 PHE B CE1 1 ATOM 4267 C CE2 . PHE B 2 114 ? 69.722 -7.386 -7.066 1.00 44.11 ? 146 PHE B CE2 1 ATOM 4268 C CZ . PHE B 2 114 ? 68.499 -6.811 -6.805 1.00 43.68 ? 146 PHE B CZ 1 ATOM 4269 N N . PRO B 2 115 ? 68.747 -13.700 -9.615 1.00 49.00 ? 147 PRO B N 1 ATOM 4270 C CA . PRO B 2 115 ? 69.050 -15.118 -9.730 1.00 46.88 ? 147 PRO B CA 1 ATOM 4271 C C . PRO B 2 115 ? 70.361 -15.537 -9.095 1.00 42.65 ? 147 PRO B C 1 ATOM 4272 O O . PRO B 2 115 ? 71.352 -14.803 -9.116 1.00 41.43 ? 147 PRO B O 1 ATOM 4273 C CB . PRO B 2 115 ? 69.126 -15.343 -11.251 1.00 47.15 ? 147 PRO B CB 1 ATOM 4274 C CG . PRO B 2 115 ? 68.356 -14.220 -11.846 1.00 48.44 ? 147 PRO B CG 1 ATOM 4275 C CD . PRO B 2 115 ? 68.673 -13.066 -10.949 1.00 48.84 ? 147 PRO B CD 1 ATOM 4276 N N . ALA B 2 116 ? 70.347 -16.723 -8.522 1.00 40.27 ? 148 ALA B N 1 ATOM 4277 C CA . ALA B 2 116 ? 71.568 -17.422 -8.300 1.00 42.19 ? 148 ALA B CA 1 ATOM 4278 C C . ALA B 2 116 ? 71.434 -18.655 -9.141 1.00 41.99 ? 148 ALA B C 1 ATOM 4279 O O . ALA B 2 116 ? 70.329 -19.050 -9.555 1.00 37.90 ? 148 ALA B O 1 ATOM 4280 C CB . ALA B 2 116 ? 71.776 -17.765 -6.830 1.00 43.35 ? 148 ALA B CB 1 ATOM 4281 N N . LEU B 2 117 ? 72.592 -19.226 -9.426 1.00 43.68 ? 149 LEU B N 1 ATOM 4282 C CA . LEU B 2 117 ? 72.654 -20.480 -10.106 1.00 43.13 ? 149 LEU B CA 1 ATOM 4283 C C . LEU B 2 117 ? 72.686 -21.553 -9.055 1.00 40.31 ? 149 LEU B C 1 ATOM 4284 O O . LEU B 2 117 ? 73.209 -21.361 -7.950 1.00 39.40 ? 149 LEU B O 1 ATOM 4285 C CB . LEU B 2 117 ? 73.888 -20.562 -11.001 1.00 43.66 ? 149 LEU B CB 1 ATOM 4286 C CG . LEU B 2 117 ? 73.802 -19.688 -12.243 1.00 42.19 ? 149 LEU B CG 1 ATOM 4287 C CD1 . LEU B 2 117 ? 75.167 -19.659 -12.910 1.00 43.70 ? 149 LEU B CD1 1 ATOM 4288 C CD2 . LEU B 2 117 ? 72.735 -20.234 -13.175 1.00 41.13 ? 149 LEU B CD2 1 ATOM 4289 N N . GLY B 2 118 ? 72.083 -22.668 -9.429 1.00 39.73 ? 150 GLY B N 1 ATOM 4290 C CA . GLY B 2 118 ? 72.093 -23.875 -8.664 1.00 38.95 ? 150 GLY B CA 1 ATOM 4291 C C . GLY B 2 118 ? 72.785 -24.870 -9.542 1.00 38.82 ? 150 GLY B C 1 ATOM 4292 O O . GLY B 2 118 ? 73.362 -24.515 -10.575 1.00 36.45 ? 150 GLY B O 1 ATOM 4293 N N . ASN B 2 119 ? 72.694 -26.121 -9.135 1.00 40.95 ? 151 ASN B N 1 ATOM 4294 C CA . ASN B 2 119 ? 73.480 -27.187 -9.732 1.00 43.58 ? 151 ASN B CA 1 ATOM 4295 C C . ASN B 2 119 ? 72.792 -28.045 -10.793 1.00 38.50 ? 151 ASN B C 1 ATOM 4296 O O . ASN B 2 119 ? 73.397 -28.948 -11.331 1.00 37.83 ? 151 ASN B O 1 ATOM 4297 C CB . ASN B 2 119 ? 74.060 -28.097 -8.624 1.00 51.07 ? 151 ASN B CB 1 ATOM 4298 C CG . ASN B 2 119 ? 72.996 -28.705 -7.722 1.00 54.93 ? 151 ASN B CG 1 ATOM 4299 O OD1 . ASN B 2 119 ? 72.240 -27.982 -7.069 1.00 64.70 ? 151 ASN B OD1 1 ATOM 4300 N ND2 . ASN B 2 119 ? 72.955 -30.040 -7.654 1.00 55.40 ? 151 ASN B ND2 1 ATOM 4301 N N . HIS B 2 120 ? 71.530 -27.829 -11.074 1.00 35.42 ? 152 HIS B N 1 ATOM 4302 C CA . HIS B 2 120 ? 70.947 -28.543 -12.173 1.00 34.70 ? 152 HIS B CA 1 ATOM 4303 C C . HIS B 2 120 ? 70.923 -27.625 -13.387 1.00 33.15 ? 152 HIS B C 1 ATOM 4304 O O . HIS B 2 120 ? 70.790 -28.087 -14.510 1.00 29.53 ? 152 HIS B O 1 ATOM 4305 C CB . HIS B 2 120 ? 69.578 -29.081 -11.782 1.00 36.57 ? 152 HIS B CB 1 ATOM 4306 C CG . HIS B 2 120 ? 69.636 -30.364 -10.997 1.00 37.29 ? 152 HIS B CG 1 ATOM 4307 N ND1 . HIS B 2 120 ? 69.296 -31.592 -11.537 1.00 37.53 ? 152 HIS B ND1 1 ATOM 4308 C CD2 . HIS B 2 120 ? 69.971 -30.608 -9.705 1.00 35.69 ? 152 HIS B CD2 1 ATOM 4309 C CE1 . HIS B 2 120 ? 69.424 -32.533 -10.613 1.00 35.84 ? 152 HIS B CE1 1 ATOM 4310 N NE2 . HIS B 2 120 ? 69.829 -31.961 -9.493 1.00 34.42 ? 152 HIS B NE2 1 ATOM 4311 N N . ASP B 2 121 ? 71.108 -26.331 -13.143 1.00 34.52 ? 153 ASP B N 1 ATOM 4312 C CA . ASP B 2 121 ? 71.232 -25.315 -14.192 1.00 36.75 ? 153 ASP B CA 1 ATOM 4313 C C . ASP B 2 121 ? 72.581 -25.453 -14.894 1.00 40.74 ? 153 ASP B C 1 ATOM 4314 O O . ASP B 2 121 ? 73.410 -24.529 -14.893 1.00 41.90 ? 153 ASP B O 1 ATOM 4315 C CB . ASP B 2 121 ? 71.158 -23.920 -13.576 1.00 35.51 ? 153 ASP B CB 1 ATOM 4316 C CG . ASP B 2 121 ? 69.976 -23.759 -12.700 1.00 34.06 ? 153 ASP B CG 1 ATOM 4317 O OD1 . ASP B 2 121 ? 68.890 -24.146 -13.142 1.00 32.87 ? 153 ASP B OD1 1 ATOM 4318 O OD2 . ASP B 2 121 ? 70.126 -23.272 -11.570 1.00 33.95 -1 153 ASP B OD2 1 ATOM 4319 N N . TYR B 2 122 ? 72.789 -26.626 -15.485 1.00 44.45 ? 154 TYR B N 1 ATOM 4320 C CA . TYR B 2 122 ? 74.038 -26.995 -16.147 1.00 44.34 ? 154 TYR B CA 1 ATOM 4321 C C . TYR B 2 122 ? 73.901 -28.447 -16.659 1.00 43.69 ? 154 TYR B C 1 ATOM 4322 O O . TYR B 2 122 ? 73.117 -29.267 -16.115 1.00 39.44 ? 154 TYR B O 1 ATOM 4323 C CB . TYR B 2 122 ? 75.241 -26.878 -15.178 1.00 44.91 ? 154 TYR B CB 1 ATOM 4324 C CG . TYR B 2 122 ? 76.573 -26.521 -15.821 1.00 45.20 ? 154 TYR B CG 1 ATOM 4325 C CD1 . TYR B 2 122 ? 77.053 -25.208 -15.798 1.00 42.61 ? 154 TYR B CD1 1 ATOM 4326 C CD2 . TYR B 2 122 ? 77.373 -27.506 -16.425 1.00 44.63 ? 154 TYR B CD2 1 ATOM 4327 C CE1 . TYR B 2 122 ? 78.267 -24.886 -16.367 1.00 41.73 ? 154 TYR B CE1 1 ATOM 4328 C CE2 . TYR B 2 122 ? 78.588 -27.182 -17.006 1.00 43.25 ? 154 TYR B CE2 1 ATOM 4329 C CZ . TYR B 2 122 ? 79.020 -25.870 -16.977 1.00 41.85 ? 154 TYR B CZ 1 ATOM 4330 O OH . TYR B 2 122 ? 80.210 -25.537 -17.558 1.00 41.12 ? 154 TYR B OH 1 ATOM 4331 N N . TRP B 2 123 ? 74.674 -28.739 -17.704 1.00 44.53 ? 155 TRP B N 1 ATOM 4332 C CA . TRP B 2 123 ? 74.830 -30.089 -18.244 1.00 44.36 ? 155 TRP B CA 1 ATOM 4333 C C . TRP B 2 123 ? 76.319 -30.520 -18.450 1.00 43.22 ? 155 TRP B C 1 ATOM 4334 O O . TRP B 2 123 ? 77.065 -29.860 -19.183 1.00 40.09 ? 155 TRP B O 1 ATOM 4335 C CB . TRP B 2 123 ? 74.074 -30.196 -19.555 1.00 45.64 ? 155 TRP B CB 1 ATOM 4336 C CG . TRP B 2 123 ? 74.030 -31.561 -19.957 1.00 49.10 ? 155 TRP B CG 1 ATOM 4337 C CD1 . TRP B 2 123 ? 73.041 -32.462 -19.698 1.00 49.09 ? 155 TRP B CD1 1 ATOM 4338 C CD2 . TRP B 2 123 ? 75.063 -32.262 -20.635 1.00 53.97 ? 155 TRP B CD2 1 ATOM 4339 N NE1 . TRP B 2 123 ? 73.386 -33.686 -20.200 1.00 51.07 ? 155 TRP B NE1 1 ATOM 4340 C CE2 . TRP B 2 123 ? 74.627 -33.592 -20.780 1.00 55.23 ? 155 TRP B CE2 1 ATOM 4341 C CE3 . TRP B 2 123 ? 76.323 -31.892 -21.144 1.00 52.20 ? 155 TRP B CE3 1 ATOM 4342 C CZ2 . TRP B 2 123 ? 75.406 -34.557 -21.411 1.00 57.44 ? 155 TRP B CZ2 1 ATOM 4343 C CZ3 . TRP B 2 123 ? 77.086 -32.835 -21.762 1.00 53.50 ? 155 TRP B CZ3 1 ATOM 4344 C CH2 . TRP B 2 123 ? 76.630 -34.159 -21.897 1.00 56.92 ? 155 TRP B CH2 1 ATOM 4345 N N . PRO B 2 124 ? 76.770 -31.607 -17.808 1.00 44.40 ? 156 PRO B N 1 ATOM 4346 C CA . PRO B 2 124 ? 76.012 -32.378 -16.795 1.00 45.30 ? 156 PRO B CA 1 ATOM 4347 C C . PRO B 2 124 ? 75.717 -31.618 -15.474 1.00 43.82 ? 156 PRO B C 1 ATOM 4348 O O . PRO B 2 124 ? 76.449 -30.693 -15.082 1.00 43.77 ? 156 PRO B O 1 ATOM 4349 C CB . PRO B 2 124 ? 76.916 -33.604 -16.518 1.00 44.96 ? 156 PRO B CB 1 ATOM 4350 C CG . PRO B 2 124 ? 78.267 -33.267 -17.041 1.00 43.46 ? 156 PRO B CG 1 ATOM 4351 C CD . PRO B 2 124 ? 78.141 -32.117 -18.004 1.00 44.64 ? 156 PRO B CD 1 ATOM 4352 N N . GLN B 2 125 ? 74.649 -32.002 -14.796 1.00 39.46 ? 157 GLN B N 1 ATOM 4353 C CA . GLN B 2 125 ? 74.382 -31.410 -13.516 1.00 38.99 ? 157 GLN B CA 1 ATOM 4354 C C . GLN B 2 125 ? 75.627 -31.365 -12.668 1.00 39.70 ? 157 GLN B C 1 ATOM 4355 O O . GLN B 2 125 ? 76.535 -32.141 -12.852 1.00 37.20 ? 157 GLN B O 1 ATOM 4356 C CB . GLN B 2 125 ? 73.275 -32.152 -12.773 1.00 39.45 ? 157 GLN B CB 1 ATOM 4357 C CG . GLN B 2 125 ? 73.489 -33.623 -12.445 1.00 37.63 ? 157 GLN B CG 1 ATOM 4358 C CD . GLN B 2 125 ? 72.157 -34.316 -12.167 1.00 37.82 ? 157 GLN B CD 1 ATOM 4359 O OE1 . GLN B 2 125 ? 71.346 -34.547 -13.087 1.00 39.84 ? 157 GLN B OE1 1 ATOM 4360 N NE2 . GLN B 2 125 ? 71.901 -34.614 -10.903 1.00 36.54 ? 157 GLN B NE2 1 ATOM 4361 N N . ASP B 2 126 ? 75.665 -30.396 -11.767 1.00 47.06 ? 158 ASP B N 1 ATOM 4362 C CA . ASP B 2 126 ? 76.721 -30.231 -10.737 1.00 51.37 ? 158 ASP B CA 1 ATOM 4363 C C . ASP B 2 126 ? 78.096 -29.733 -11.214 1.00 49.05 ? 158 ASP B C 1 ATOM 4364 O O . ASP B 2 126 ? 78.899 -29.292 -10.399 1.00 52.49 ? 158 ASP B O 1 ATOM 4365 C CB . ASP B 2 126 ? 76.915 -31.516 -9.898 1.00 53.96 ? 158 ASP B CB 1 ATOM 4366 C CG . ASP B 2 126 ? 75.599 -32.107 -9.376 1.00 57.83 ? 158 ASP B CG 1 ATOM 4367 O OD1 . ASP B 2 126 ? 74.558 -31.400 -9.361 1.00 54.23 ? 158 ASP B OD1 1 ATOM 4368 O OD2 . ASP B 2 126 ? 75.622 -33.301 -8.983 1.00 60.93 -1 158 ASP B OD2 1 ATOM 4369 N N . GLN B 2 127 ? 78.370 -29.750 -12.508 1.00 44.60 ? 159 GLN B N 1 ATOM 4370 C CA . GLN B 2 127 ? 79.734 -29.592 -12.951 1.00 42.89 ? 159 GLN B CA 1 ATOM 4371 C C . GLN B 2 127 ? 80.114 -28.135 -13.209 1.00 46.66 ? 159 GLN B C 1 ATOM 4372 O O . GLN B 2 127 ? 80.982 -27.839 -14.023 1.00 53.01 ? 159 GLN B O 1 ATOM 4373 C CB . GLN B 2 127 ? 79.935 -30.458 -14.181 1.00 40.72 ? 159 GLN B CB 1 ATOM 4374 C CG . GLN B 2 127 ? 79.565 -31.905 -13.930 1.00 39.99 ? 159 GLN B CG 1 ATOM 4375 C CD . GLN B 2 127 ? 80.285 -32.458 -12.723 1.00 40.25 ? 159 GLN B CD 1 ATOM 4376 O OE1 . GLN B 2 127 ? 81.511 -32.507 -12.694 1.00 43.64 ? 159 GLN B OE1 1 ATOM 4377 N NE2 . GLN B 2 127 ? 79.540 -32.853 -11.721 1.00 39.13 ? 159 GLN B NE2 1 ATOM 4378 N N . LEU B 2 128 ? 79.505 -27.212 -12.481 1.00 48.91 ? 160 LEU B N 1 ATOM 4379 C CA . LEU B 2 128 ? 79.699 -25.801 -12.781 1.00 47.86 ? 160 LEU B CA 1 ATOM 4380 C C . LEU B 2 128 ? 81.191 -25.559 -12.666 1.00 46.08 ? 160 LEU B C 1 ATOM 4381 O O . LEU B 2 128 ? 81.812 -26.078 -11.755 1.00 41.26 ? 160 LEU B O 1 ATOM 4382 C CB . LEU B 2 128 ? 78.866 -24.893 -11.856 1.00 49.12 ? 160 LEU B CB 1 ATOM 4383 C CG . LEU B 2 128 ? 77.346 -24.816 -12.173 1.00 50.34 ? 160 LEU B CG 1 ATOM 4384 C CD1 . LEU B 2 128 ? 76.562 -25.997 -11.589 1.00 50.57 ? 160 LEU B CD1 1 ATOM 4385 C CD2 . LEU B 2 128 ? 76.690 -23.520 -11.716 1.00 49.87 ? 160 LEU B CD2 1 ATOM 4386 N N . PRO B 2 129 ? 81.778 -24.854 -13.651 1.00 51.31 ? 161 PRO B N 1 ATOM 4387 C CA . PRO B 2 129 ? 83.215 -24.593 -13.730 1.00 54.15 ? 161 PRO B CA 1 ATOM 4388 C C . PRO B 2 129 ? 83.777 -23.255 -13.144 1.00 57.01 ? 161 PRO B C 1 ATOM 4389 O O . PRO B 2 129 ? 83.041 -22.369 -12.636 1.00 48.15 ? 161 PRO B O 1 ATOM 4390 C CB . PRO B 2 129 ? 83.461 -24.638 -15.242 1.00 52.00 ? 161 PRO B CB 1 ATOM 4391 C CG . PRO B 2 129 ? 82.234 -24.007 -15.792 1.00 50.09 ? 161 PRO B CG 1 ATOM 4392 C CD . PRO B 2 129 ? 81.143 -24.629 -14.963 1.00 50.96 ? 161 PRO B CD 1 ATOM 4393 N N . VAL B 2 130 ? 85.109 -23.179 -13.251 1.00 62.94 ? 162 VAL B N 1 ATOM 4394 C CA . VAL B 2 130 ? 85.978 -22.105 -12.754 1.00 65.46 ? 162 VAL B CA 1 ATOM 4395 C C . VAL B 2 130 ? 86.109 -20.956 -13.744 1.00 62.57 ? 162 VAL B C 1 ATOM 4396 O O . VAL B 2 130 ? 86.156 -19.785 -13.356 1.00 65.12 ? 162 VAL B O 1 ATOM 4397 C CB . VAL B 2 130 ? 87.412 -22.666 -12.540 1.00 71.53 ? 162 VAL B CB 1 ATOM 4398 C CG1 . VAL B 2 130 ? 88.447 -21.555 -12.260 1.00 70.38 ? 162 VAL B CG1 1 ATOM 4399 C CG2 . VAL B 2 130 ? 87.398 -23.757 -11.464 1.00 72.21 ? 162 VAL B CG2 1 ATOM 4400 N N . VAL B 2 131 ? 86.201 -21.312 -15.023 1.00 58.10 ? 163 VAL B N 1 ATOM 4401 C CA . VAL B 2 131 ? 86.412 -20.344 -16.092 1.00 54.15 ? 163 VAL B CA 1 ATOM 4402 C C . VAL B 2 131 ? 85.134 -20.288 -16.921 1.00 55.25 ? 163 VAL B C 1 ATOM 4403 O O . VAL B 2 131 ? 84.208 -21.079 -16.700 1.00 53.03 ? 163 VAL B O 1 ATOM 4404 C CB . VAL B 2 131 ? 87.614 -20.722 -16.976 1.00 51.46 ? 163 VAL B CB 1 ATOM 4405 C CG1 . VAL B 2 131 ? 88.463 -19.487 -17.255 1.00 50.80 ? 163 VAL B CG1 1 ATOM 4406 C CG2 . VAL B 2 131 ? 88.467 -21.802 -16.313 1.00 49.51 ? 163 VAL B CG2 1 ATOM 4407 N N . THR B 2 132 ? 85.073 -19.352 -17.866 1.00 58.87 ? 164 THR B N 1 ATOM 4408 C CA . THR B 2 132 ? 83.824 -19.091 -18.608 1.00 60.16 ? 164 THR B CA 1 ATOM 4409 C C . THR B 2 132 ? 83.288 -20.333 -19.370 1.00 59.82 ? 164 THR B C 1 ATOM 4410 O O . THR B 2 132 ? 84.005 -21.324 -19.555 1.00 63.50 ? 164 THR B O 1 ATOM 4411 C CB . THR B 2 132 ? 83.959 -17.862 -19.547 1.00 59.38 ? 164 THR B CB 1 ATOM 4412 O OG1 . THR B 2 132 ? 82.666 -17.471 -20.042 1.00 53.52 ? 164 THR B OG1 1 ATOM 4413 C CG2 . THR B 2 132 ? 84.932 -18.160 -20.714 1.00 61.92 ? 164 THR B CG2 1 ATOM 4414 N N . SER B 2 133 ? 82.021 -20.268 -19.788 1.00 55.98 ? 165 SER B N 1 ATOM 4415 C CA . SER B 2 133 ? 81.321 -21.419 -20.353 1.00 51.03 ? 165 SER B CA 1 ATOM 4416 C C . SER B 2 133 ? 80.113 -20.948 -21.128 1.00 46.89 ? 165 SER B C 1 ATOM 4417 O O . SER B 2 133 ? 79.670 -19.811 -20.972 1.00 40.33 ? 165 SER B O 1 ATOM 4418 C CB . SER B 2 133 ? 80.841 -22.351 -19.236 1.00 50.90 ? 165 SER B CB 1 ATOM 4419 O OG . SER B 2 133 ? 79.715 -21.780 -18.573 1.00 51.08 ? 165 SER B OG 1 ATOM 4420 N N . LYS B 2 134 ? 79.570 -21.857 -21.927 1.00 46.57 ? 166 LYS B N 1 ATOM 4421 C CA . LYS B 2 134 ? 78.331 -21.615 -22.660 1.00 48.85 ? 166 LYS B CA 1 ATOM 4422 C C . LYS B 2 134 ? 77.141 -21.186 -21.771 1.00 49.95 ? 166 LYS B C 1 ATOM 4423 O O . LYS B 2 134 ? 76.538 -20.131 -22.018 1.00 44.62 ? 166 LYS B O 1 ATOM 4424 C CB . LYS B 2 134 ? 77.954 -22.864 -23.470 1.00 51.00 ? 166 LYS B CB 1 ATOM 4425 C CG . LYS B 2 134 ? 76.894 -22.617 -24.547 1.00 51.94 ? 166 LYS B CG 1 ATOM 4426 C CD . LYS B 2 134 ? 76.736 -23.814 -25.477 1.00 51.19 ? 166 LYS B CD 1 ATOM 4427 C CE . LYS B 2 134 ? 75.834 -23.496 -26.651 1.00 51.28 ? 166 LYS B CE 1 ATOM 4428 N NZ . LYS B 2 134 ? 75.436 -24.763 -27.314 1.00 52.86 1 166 LYS B NZ 1 ATOM 4429 N N . VAL B 2 135 ? 76.799 -21.996 -20.758 1.00 52.06 ? 167 VAL B N 1 ATOM 4430 C CA . VAL B 2 135 ? 75.628 -21.701 -19.894 1.00 53.17 ? 167 VAL B CA 1 ATOM 4431 C C . VAL B 2 135 ? 75.826 -20.406 -19.075 1.00 50.69 ? 167 VAL B C 1 ATOM 4432 O O . VAL B 2 135 ? 74.871 -19.612 -18.918 1.00 46.86 ? 167 VAL B O 1 ATOM 4433 C CB . VAL B 2 135 ? 75.187 -22.916 -18.997 1.00 53.84 ? 167 VAL B CB 1 ATOM 4434 C CG1 . VAL B 2 135 ? 76.212 -23.245 -17.938 1.00 53.49 ? 167 VAL B CG1 1 ATOM 4435 C CG2 . VAL B 2 135 ? 73.829 -22.678 -18.330 1.00 53.06 ? 167 VAL B CG2 1 ATOM 4436 N N . TYR B 2 136 ? 77.050 -20.175 -18.589 1.00 45.75 ? 168 TYR B N 1 ATOM 4437 C CA . TYR B 2 136 ? 77.335 -18.921 -17.886 1.00 45.61 ? 168 TYR B CA 1 ATOM 4438 C C . TYR B 2 136 ? 77.052 -17.693 -18.777 1.00 45.38 ? 168 TYR B C 1 ATOM 4439 O O . TYR B 2 136 ? 76.301 -16.792 -18.382 1.00 40.43 ? 168 TYR B O 1 ATOM 4440 C CB . TYR B 2 136 ? 78.776 -18.876 -17.354 1.00 44.24 ? 168 TYR B CB 1 ATOM 4441 C CG . TYR B 2 136 ? 79.112 -19.775 -16.166 1.00 42.04 ? 168 TYR B CG 1 ATOM 4442 C CD1 . TYR B 2 136 ? 78.137 -20.462 -15.428 1.00 41.48 ? 168 TYR B CD1 1 ATOM 4443 C CD2 . TYR B 2 136 ? 80.425 -19.902 -15.768 1.00 41.88 ? 168 TYR B CD2 1 ATOM 4444 C CE1 . TYR B 2 136 ? 78.493 -21.280 -14.354 1.00 41.26 ? 168 TYR B CE1 1 ATOM 4445 C CE2 . TYR B 2 136 ? 80.787 -20.706 -14.707 1.00 42.87 ? 168 TYR B CE2 1 ATOM 4446 C CZ . TYR B 2 136 ? 79.834 -21.390 -13.996 1.00 41.73 ? 168 TYR B CZ 1 ATOM 4447 O OH . TYR B 2 136 ? 80.295 -22.160 -12.945 1.00 40.52 ? 168 TYR B OH 1 ATOM 4448 N N . ASN B 2 137 ? 77.645 -17.678 -19.975 1.00 49.71 ? 169 ASN B N 1 ATOM 4449 C CA . ASN B 2 137 ? 77.417 -16.604 -20.974 1.00 50.85 ? 169 ASN B CA 1 ATOM 4450 C C . ASN B 2 137 ? 75.975 -16.537 -21.474 1.00 51.56 ? 169 ASN B C 1 ATOM 4451 O O . ASN B 2 137 ? 75.527 -15.475 -21.921 1.00 47.28 ? 169 ASN B O 1 ATOM 4452 C CB . ASN B 2 137 ? 78.323 -16.791 -22.195 1.00 50.53 ? 169 ASN B CB 1 ATOM 4453 C CG . ASN B 2 137 ? 79.752 -16.430 -21.913 1.00 49.97 ? 169 ASN B CG 1 ATOM 4454 O OD1 . ASN B 2 137 ? 80.565 -17.282 -21.554 1.00 50.22 ? 169 ASN B OD1 1 ATOM 4455 N ND2 . ASN B 2 137 ? 80.069 -15.161 -22.060 1.00 50.63 ? 169 ASN B ND2 1 ATOM 4456 N N . ALA B 2 138 ? 75.292 -17.693 -21.439 1.00 53.79 ? 170 ALA B N 1 ATOM 4457 C CA . ALA B 2 138 ? 73.874 -17.844 -21.841 1.00 52.39 ? 170 ALA B CA 1 ATOM 4458 C C . ALA B 2 138 ? 72.909 -17.091 -20.910 1.00 52.40 ? 170 ALA B C 1 ATOM 4459 O O . ALA B 2 138 ? 72.009 -16.374 -21.374 1.00 46.65 ? 170 ALA B O 1 ATOM 4460 C CB . ALA B 2 138 ? 73.497 -19.333 -21.896 1.00 49.20 ? 170 ALA B CB 1 ATOM 4461 N N . VAL B 2 139 ? 73.118 -17.286 -19.602 1.00 52.50 ? 171 VAL B N 1 ATOM 4462 C CA . VAL B 2 139 ? 72.298 -16.685 -18.546 1.00 47.20 ? 171 VAL B CA 1 ATOM 4463 C C . VAL B 2 139 ? 72.597 -15.191 -18.324 1.00 47.72 ? 171 VAL B C 1 ATOM 4464 O O . VAL B 2 139 ? 71.665 -14.423 -18.063 1.00 43.95 ? 171 VAL B O 1 ATOM 4465 C CB . VAL B 2 139 ? 72.441 -17.481 -17.240 1.00 44.00 ? 171 VAL B CB 1 ATOM 4466 C CG1 . VAL B 2 139 ? 72.024 -18.918 -17.464 1.00 44.06 ? 171 VAL B CG1 1 ATOM 4467 C CG2 . VAL B 2 139 ? 73.863 -17.446 -16.714 1.00 43.95 ? 171 VAL B CG2 1 ATOM 4468 N N . ALA B 2 140 ? 73.870 -14.779 -18.453 1.00 48.83 ? 172 ALA B N 1 ATOM 4469 C CA . ALA B 2 140 ? 74.241 -13.345 -18.408 1.00 52.04 ? 172 ALA B CA 1 ATOM 4470 C C . ALA B 2 140 ? 73.419 -12.532 -19.412 1.00 53.98 ? 172 ALA B C 1 ATOM 4471 O O . ALA B 2 140 ? 72.884 -11.475 -19.062 1.00 52.06 ? 172 ALA B O 1 ATOM 4472 C CB . ALA B 2 140 ? 75.736 -13.138 -18.651 1.00 51.05 ? 172 ALA B CB 1 ATOM 4473 N N . ASN B 2 141 ? 73.311 -13.048 -20.642 1.00 57.62 ? 173 ASN B N 1 ATOM 4474 C CA . ASN B 2 141 ? 72.411 -12.484 -21.679 1.00 62.10 ? 173 ASN B CA 1 ATOM 4475 C C . ASN B 2 141 ? 70.967 -12.434 -21.189 1.00 59.98 ? 173 ASN B C 1 ATOM 4476 O O . ASN B 2 141 ? 70.292 -11.439 -21.372 1.00 63.84 ? 173 ASN B O 1 ATOM 4477 C CB . ASN B 2 141 ? 72.417 -13.291 -23.008 1.00 65.86 ? 173 ASN B CB 1 ATOM 4478 C CG . ASN B 2 141 ? 73.790 -13.351 -23.697 1.00 72.04 ? 173 ASN B CG 1 ATOM 4479 O OD1 . ASN B 2 141 ? 74.743 -12.652 -23.329 1.00 76.20 ? 173 ASN B OD1 1 ATOM 4480 N ND2 . ASN B 2 141 ? 73.886 -14.204 -24.716 1.00 73.89 ? 173 ASN B ND2 1 ATOM 4481 N N . LEU B 2 142 ? 70.499 -13.517 -20.577 1.00 57.61 ? 174 LEU B N 1 ATOM 4482 C CA . LEU B 2 142 ? 69.125 -13.606 -20.118 1.00 53.08 ? 174 LEU B CA 1 ATOM 4483 C C . LEU B 2 142 ? 68.818 -12.618 -19.001 1.00 51.00 ? 174 LEU B C 1 ATOM 4484 O O . LEU B 2 142 ? 67.714 -12.070 -18.904 1.00 46.67 ? 174 LEU B O 1 ATOM 4485 C CB . LEU B 2 142 ? 68.845 -15.021 -19.647 1.00 55.59 ? 174 LEU B CB 1 ATOM 4486 C CG . LEU B 2 142 ? 68.975 -16.118 -20.708 1.00 61.44 ? 174 LEU B CG 1 ATOM 4487 C CD1 . LEU B 2 142 ? 68.626 -17.481 -20.107 1.00 64.25 ? 174 LEU B CD1 1 ATOM 4488 C CD2 . LEU B 2 142 ? 68.105 -15.852 -21.934 1.00 61.34 ? 174 LEU B CD2 1 ATOM 4489 N N . TRP B 2 143 ? 69.801 -12.368 -18.159 1.00 50.19 ? 175 TRP B N 1 ATOM 4490 C CA . TRP B 2 143 ? 69.549 -11.567 -16.985 1.00 52.18 ? 175 TRP B CA 1 ATOM 4491 C C . TRP B 2 143 ? 70.059 -10.143 -17.105 1.00 53.36 ? 175 TRP B C 1 ATOM 4492 O O . TRP B 2 143 ? 69.914 -9.353 -16.176 1.00 49.88 ? 175 TRP B O 1 ATOM 4493 C CB . TRP B 2 143 ? 70.111 -12.294 -15.769 1.00 53.52 ? 175 TRP B CB 1 ATOM 4494 C CG . TRP B 2 143 ? 69.537 -13.689 -15.630 1.00 53.64 ? 175 TRP B CG 1 ATOM 4495 C CD1 . TRP B 2 143 ? 68.347 -14.163 -16.157 1.00 53.42 ? 175 TRP B CD1 1 ATOM 4496 C CD2 . TRP B 2 143 ? 70.107 -14.772 -14.902 1.00 54.82 ? 175 TRP B CD2 1 ATOM 4497 N NE1 . TRP B 2 143 ? 68.157 -15.480 -15.810 1.00 54.98 ? 175 TRP B NE1 1 ATOM 4498 C CE2 . TRP B 2 143 ? 69.219 -15.882 -15.035 1.00 59.12 ? 175 TRP B CE2 1 ATOM 4499 C CE3 . TRP B 2 143 ? 71.280 -14.921 -14.140 1.00 54.62 ? 175 TRP B CE3 1 ATOM 4500 C CZ2 . TRP B 2 143 ? 69.479 -17.122 -14.437 1.00 60.35 ? 175 TRP B CZ2 1 ATOM 4501 C CZ3 . TRP B 2 143 ? 71.545 -16.150 -13.550 1.00 56.79 ? 175 TRP B CZ3 1 ATOM 4502 C CH2 . TRP B 2 143 ? 70.643 -17.237 -13.700 1.00 61.67 ? 175 TRP B CH2 1 ATOM 4503 N N . LYS B 2 144 ? 70.629 -9.808 -18.264 1.00 58.64 ? 176 LYS B N 1 ATOM 4504 C CA . LYS B 2 144 ? 70.893 -8.406 -18.643 1.00 59.06 ? 176 LYS B CA 1 ATOM 4505 C C . LYS B 2 144 ? 69.788 -7.447 -18.153 1.00 56.69 ? 176 LYS B C 1 ATOM 4506 O O . LYS B 2 144 ? 70.099 -6.468 -17.464 1.00 56.30 ? 176 LYS B O 1 ATOM 4507 C CB . LYS B 2 144 ? 71.048 -8.248 -20.181 1.00 59.31 ? 176 LYS B CB 1 ATOM 4508 C CG . LYS B 2 144 ? 72.473 -8.162 -20.757 1.00 57.94 ? 176 LYS B CG 1 ATOM 4509 C CD . LYS B 2 144 ? 72.493 -8.078 -22.297 1.00 54.96 ? 176 LYS B CD 1 ATOM 4510 C CE . LYS B 2 144 ? 71.623 -6.944 -22.860 1.00 53.90 ? 176 LYS B CE 1 ATOM 4511 N NZ . LYS B 2 144 ? 71.259 -7.135 -24.290 1.00 52.55 1 176 LYS B NZ 1 ATOM 4512 N N . PRO B 2 145 ? 68.497 -7.718 -18.492 1.00 54.54 ? 177 PRO B N 1 ATOM 4513 C CA . PRO B 2 145 ? 67.547 -6.656 -18.140 1.00 55.92 ? 177 PRO B CA 1 ATOM 4514 C C . PRO B 2 145 ? 67.559 -6.333 -16.633 1.00 60.84 ? 177 PRO B C 1 ATOM 4515 O O . PRO B 2 145 ? 67.206 -5.206 -16.274 1.00 69.10 ? 177 PRO B O 1 ATOM 4516 C CB . PRO B 2 145 ? 66.170 -7.198 -18.620 1.00 51.32 ? 177 PRO B CB 1 ATOM 4517 C CG . PRO B 2 145 ? 66.472 -8.395 -19.456 1.00 51.11 ? 177 PRO B CG 1 ATOM 4518 C CD . PRO B 2 145 ? 67.793 -8.930 -18.960 1.00 53.15 ? 177 PRO B CD 1 ATOM 4519 N N . TRP B 2 146 ? 67.990 -7.290 -15.787 1.00 58.06 ? 178 TRP B N 1 ATOM 4520 C CA . TRP B 2 146 ? 68.038 -7.123 -14.316 1.00 56.03 ? 178 TRP B CA 1 ATOM 4521 C C . TRP B 2 146 ? 69.384 -6.667 -13.722 1.00 60.60 ? 178 TRP B C 1 ATOM 4522 O O . TRP B 2 146 ? 69.372 -5.925 -12.746 1.00 68.94 ? 178 TRP B O 1 ATOM 4523 C CB . TRP B 2 146 ? 67.622 -8.410 -13.585 1.00 51.10 ? 178 TRP B CB 1 ATOM 4524 C CG . TRP B 2 146 ? 66.259 -8.944 -13.935 1.00 45.20 ? 178 TRP B CG 1 ATOM 4525 C CD1 . TRP B 2 146 ? 65.122 -8.215 -14.175 1.00 42.70 ? 178 TRP B CD1 1 ATOM 4526 C CD2 . TRP B 2 146 ? 65.886 -10.337 -14.053 1.00 39.75 ? 178 TRP B CD2 1 ATOM 4527 N NE1 . TRP B 2 146 ? 64.071 -9.072 -14.446 1.00 42.33 ? 178 TRP B NE1 1 ATOM 4528 C CE2 . TRP B 2 146 ? 64.513 -10.373 -14.383 1.00 39.05 ? 178 TRP B CE2 1 ATOM 4529 C CE3 . TRP B 2 146 ? 66.580 -11.555 -13.900 1.00 35.11 ? 178 TRP B CE3 1 ATOM 4530 C CZ2 . TRP B 2 146 ? 63.821 -11.580 -14.570 1.00 35.41 ? 178 TRP B CZ2 1 ATOM 4531 C CZ3 . TRP B 2 146 ? 65.887 -12.752 -14.089 1.00 33.05 ? 178 TRP B CZ3 1 ATOM 4532 C CH2 . TRP B 2 146 ? 64.525 -12.751 -14.420 1.00 33.29 ? 178 TRP B CH2 1 ATOM 4533 N N . LEU B 2 147 ? 70.524 -7.110 -14.259 1.00 61.89 ? 179 LEU B N 1 ATOM 4534 C CA . LEU B 2 147 ? 71.846 -6.690 -13.730 1.00 62.73 ? 179 LEU B CA 1 ATOM 4535 C C . LEU B 2 147 ? 72.548 -5.720 -14.670 1.00 67.94 ? 179 LEU B C 1 ATOM 4536 O O . LEU B 2 147 ? 72.033 -5.397 -15.746 1.00 77.57 ? 179 LEU B O 1 ATOM 4537 C CB . LEU B 2 147 ? 72.760 -7.892 -13.498 1.00 61.17 ? 179 LEU B CB 1 ATOM 4538 C CG . LEU B 2 147 ? 72.090 -9.188 -13.067 1.00 57.54 ? 179 LEU B CG 1 ATOM 4539 C CD1 . LEU B 2 147 ? 73.175 -10.234 -12.885 1.00 55.89 ? 179 LEU B CD1 1 ATOM 4540 C CD2 . LEU B 2 147 ? 71.288 -8.975 -11.795 1.00 55.31 ? 179 LEU B CD2 1 ATOM 4541 N N . ASP B 2 148 ? 73.727 -5.256 -14.282 1.00 66.97 ? 180 ASP B N 1 ATOM 4542 C CA . ASP B 2 148 ? 74.440 -4.318 -15.129 1.00 68.67 ? 180 ASP B CA 1 ATOM 4543 C C . ASP B 2 148 ? 75.846 -4.809 -15.372 1.00 73.68 ? 180 ASP B C 1 ATOM 4544 O O . ASP B 2 148 ? 76.245 -5.820 -14.806 1.00 76.93 ? 180 ASP B O 1 ATOM 4545 C CB . ASP B 2 148 ? 74.344 -2.927 -14.521 1.00 69.23 ? 180 ASP B CB 1 ATOM 4546 C CG . ASP B 2 148 ? 72.890 -2.463 -14.406 1.00 72.07 ? 180 ASP B CG 1 ATOM 4547 O OD1 . ASP B 2 148 ? 72.206 -2.396 -15.451 1.00 69.78 ? 180 ASP B OD1 1 ATOM 4548 O OD2 . ASP B 2 148 ? 72.408 -2.210 -13.280 1.00 74.16 -1 180 ASP B OD2 1 ATOM 4549 N N . GLU B 2 149 ? 76.577 -4.113 -16.241 1.00 79.78 ? 181 GLU B N 1 ATOM 4550 C CA . GLU B 2 149 ? 77.832 -4.628 -16.819 1.00 82.20 ? 181 GLU B CA 1 ATOM 4551 C C . GLU B 2 149 ? 78.761 -5.307 -15.805 1.00 84.62 ? 181 GLU B C 1 ATOM 4552 O O . GLU B 2 149 ? 79.293 -6.387 -16.092 1.00 89.01 ? 181 GLU B O 1 ATOM 4553 C CB . GLU B 2 149 ? 78.635 -3.517 -17.499 1.00 83.47 ? 181 GLU B CB 1 ATOM 4554 C CG . GLU B 2 149 ? 77.932 -2.743 -18.606 1.00 85.78 ? 181 GLU B CG 1 ATOM 4555 C CD . GLU B 2 149 ? 78.368 -1.280 -18.652 1.00 87.24 ? 181 GLU B CD 1 ATOM 4556 O OE1 . GLU B 2 149 ? 79.422 -0.942 -18.060 1.00 83.04 ? 181 GLU B OE1 1 ATOM 4557 O OE2 . GLU B 2 149 ? 77.657 -0.460 -19.277 1.00 83.98 -1 181 GLU B OE2 1 ATOM 4558 N N . GLU B 2 150 ? 78.963 -4.674 -14.641 1.00 81.58 ? 182 GLU B N 1 ATOM 4559 C CA . GLU B 2 150 ? 79.913 -5.182 -13.622 1.00 82.04 ? 182 GLU B CA 1 ATOM 4560 C C . GLU B 2 150 ? 79.398 -6.511 -13.082 1.00 84.65 ? 182 GLU B C 1 ATOM 4561 O O . GLU B 2 150 ? 80.172 -7.463 -12.891 1.00 84.49 ? 182 GLU B O 1 ATOM 4562 C CB . GLU B 2 150 ? 80.109 -4.219 -12.439 1.00 78.90 ? 182 GLU B CB 1 ATOM 4563 C CG . GLU B 2 150 ? 80.461 -2.794 -12.813 1.00 79.06 ? 182 GLU B CG 1 ATOM 4564 C CD . GLU B 2 150 ? 79.258 -2.016 -13.307 1.00 76.81 ? 182 GLU B CD 1 ATOM 4565 O OE1 . GLU B 2 150 ? 78.163 -2.167 -12.719 1.00 73.47 ? 182 GLU B OE1 1 ATOM 4566 O OE2 . GLU B 2 150 ? 79.406 -1.271 -14.297 1.00 73.97 -1 182 GLU B OE2 1 ATOM 4567 N N . ALA B 2 151 ? 78.087 -6.551 -12.826 1.00 79.46 ? 183 ALA B N 1 ATOM 4568 C CA . ALA B 2 151 ? 77.394 -7.786 -12.474 1.00 73.47 ? 183 ALA B CA 1 ATOM 4569 C C . ALA B 2 151 ? 77.600 -8.811 -13.582 1.00 69.82 ? 183 ALA B C 1 ATOM 4570 O O . ALA B 2 151 ? 78.147 -9.894 -13.340 1.00 69.00 ? 183 ALA B O 1 ATOM 4571 C CB . ALA B 2 151 ? 75.902 -7.526 -12.252 1.00 70.68 ? 183 ALA B CB 1 ATOM 4572 N N . ILE B 2 152 ? 77.194 -8.422 -14.794 1.00 63.37 ? 184 ILE B N 1 ATOM 4573 C CA . ILE B 2 152 ? 77.213 -9.277 -15.978 1.00 59.14 ? 184 ILE B CA 1 ATOM 4574 C C . ILE B 2 152 ? 78.581 -9.860 -16.284 1.00 56.97 ? 184 ILE B C 1 ATOM 4575 O O . ILE B 2 152 ? 78.688 -11.010 -16.717 1.00 52.21 ? 184 ILE B O 1 ATOM 4576 C CB . ILE B 2 152 ? 76.730 -8.487 -17.200 1.00 63.00 ? 184 ILE B CB 1 ATOM 4577 C CG1 . ILE B 2 152 ? 75.215 -8.258 -17.112 1.00 67.44 ? 184 ILE B CG1 1 ATOM 4578 C CG2 . ILE B 2 152 ? 77.085 -9.198 -18.503 1.00 66.19 ? 184 ILE B CG2 1 ATOM 4579 C CD1 . ILE B 2 152 ? 74.374 -9.517 -17.279 1.00 69.14 ? 184 ILE B CD1 1 ATOM 4580 N N . SER B 2 153 ? 79.611 -9.053 -16.067 1.00 57.69 ? 185 SER B N 1 ATOM 4581 C CA . SER B 2 153 ? 80.995 -9.456 -16.297 1.00 59.71 ? 185 SER B CA 1 ATOM 4582 C C . SER B 2 153 ? 81.431 -10.715 -15.539 1.00 59.40 ? 185 SER B C 1 ATOM 4583 O O . SER B 2 153 ? 81.800 -11.697 -16.164 1.00 55.74 ? 185 SER B O 1 ATOM 4584 C CB . SER B 2 153 ? 81.947 -8.312 -15.951 1.00 60.00 ? 185 SER B CB 1 ATOM 4585 O OG . SER B 2 153 ? 83.267 -8.815 -15.852 1.00 62.82 ? 185 SER B OG 1 ATOM 4586 N N . THR B 2 154 ? 81.421 -10.678 -14.204 1.00 64.96 ? 186 THR B N 1 ATOM 4587 C CA . THR B 2 154 ? 81.794 -11.866 -13.401 1.00 67.56 ? 186 THR B CA 1 ATOM 4588 C C . THR B 2 154 ? 80.770 -13.012 -13.558 1.00 61.86 ? 186 THR B C 1 ATOM 4589 O O . THR B 2 154 ? 81.110 -14.174 -13.329 1.00 58.99 ? 186 THR B O 1 ATOM 4590 C CB . THR B 2 154 ? 82.013 -11.581 -11.867 1.00 70.31 ? 186 THR B CB 1 ATOM 4591 O OG1 . THR B 2 154 ? 81.114 -10.557 -11.406 1.00 73.08 ? 186 THR B OG1 1 ATOM 4592 C CG2 . THR B 2 154 ? 83.501 -11.206 -11.537 1.00 69.46 ? 186 THR B CG2 1 ATOM 4593 N N . LEU B 2 155 ? 79.533 -12.693 -13.945 1.00 57.32 ? 187 LEU B N 1 ATOM 4594 C CA . LEU B 2 155 ? 78.499 -13.728 -14.166 1.00 56.18 ? 187 LEU B CA 1 ATOM 4595 C C . LEU B 2 155 ? 78.830 -14.767 -15.274 1.00 56.91 ? 187 LEU B C 1 ATOM 4596 O O . LEU B 2 155 ? 78.350 -15.896 -15.194 1.00 58.99 ? 187 LEU B O 1 ATOM 4597 C CB . LEU B 2 155 ? 77.125 -13.073 -14.418 1.00 53.22 ? 187 LEU B CB 1 ATOM 4598 C CG . LEU B 2 155 ? 75.906 -13.961 -14.679 1.00 49.90 ? 187 LEU B CG 1 ATOM 4599 C CD1 . LEU B 2 155 ? 75.719 -15.042 -13.634 1.00 50.24 ? 187 LEU B CD1 1 ATOM 4600 C CD2 . LEU B 2 155 ? 74.679 -13.083 -14.738 1.00 48.26 ? 187 LEU B CD2 1 ATOM 4601 N N . ARG B 2 156 ? 79.639 -14.391 -16.279 1.00 55.50 ? 188 ARG B N 1 ATOM 4602 C CA . ARG B 2 156 ? 80.093 -15.317 -17.329 1.00 50.47 ? 188 ARG B CA 1 ATOM 4603 C C . ARG B 2 156 ? 81.481 -15.896 -17.032 1.00 51.19 ? 188 ARG B C 1 ATOM 4604 O O . ARG B 2 156 ? 81.878 -16.852 -17.677 1.00 46.82 ? 188 ARG B O 1 ATOM 4605 C CB . ARG B 2 156 ? 80.178 -14.653 -18.697 1.00 51.56 ? 188 ARG B CB 1 ATOM 4606 C CG . ARG B 2 156 ? 79.331 -13.423 -18.979 1.00 52.60 ? 188 ARG B CG 1 ATOM 4607 C CD . ARG B 2 156 ? 80.064 -12.590 -20.032 1.00 55.44 ? 188 ARG B CD 1 ATOM 4608 N NE . ARG B 2 156 ? 79.286 -11.477 -20.525 1.00 57.16 ? 188 ARG B NE 1 ATOM 4609 C CZ . ARG B 2 156 ? 78.232 -11.591 -21.322 1.00 60.11 ? 188 ARG B CZ 1 ATOM 4610 N NH1 . ARG B 2 156 ? 77.808 -12.785 -21.743 1.00 59.98 1 188 ARG B NH1 1 ATOM 4611 N NH2 . ARG B 2 156 ? 77.595 -10.493 -21.699 1.00 63.65 ? 188 ARG B NH2 1 ATOM 4612 N N . LYS B 2 157 ? 82.231 -15.268 -16.115 1.00 55.62 ? 189 LYS B N 1 ATOM 4613 C CA . LYS B 2 157 ? 83.534 -15.782 -15.577 1.00 60.09 ? 189 LYS B CA 1 ATOM 4614 C C . LYS B 2 157 ? 83.400 -17.056 -14.702 1.00 54.07 ? 189 LYS B C 1 ATOM 4615 O O . LYS B 2 157 ? 84.082 -18.050 -14.910 1.00 46.59 ? 189 LYS B O 1 ATOM 4616 C CB . LYS B 2 157 ? 84.249 -14.698 -14.709 1.00 66.59 ? 189 LYS B CB 1 ATOM 4617 C CG . LYS B 2 157 ? 85.241 -13.745 -15.386 1.00 69.04 ? 189 LYS B CG 1 ATOM 4618 C CD . LYS B 2 157 ? 84.582 -12.814 -16.396 1.00 72.44 ? 189 LYS B CD 1 ATOM 4619 C CE . LYS B 2 157 ? 84.532 -13.446 -17.798 1.00 74.27 ? 189 LYS B CE 1 ATOM 4620 N NZ . LYS B 2 157 ? 83.556 -12.829 -18.747 1.00 70.98 1 189 LYS B NZ 1 ATOM 4621 N N . GLY B 2 158 ? 82.559 -16.980 -13.679 1.00 53.25 ? 190 GLY B N 1 ATOM 4622 C CA . GLY B 2 158 ? 82.326 -18.104 -12.781 1.00 53.14 ? 190 GLY B CA 1 ATOM 4623 C C . GLY B 2 158 ? 80.921 -18.205 -12.182 1.00 54.51 ? 190 GLY B C 1 ATOM 4624 O O . GLY B 2 158 ? 80.745 -18.900 -11.181 1.00 56.48 ? 190 GLY B O 1 ATOM 4625 N N . GLY B 2 159 ? 79.925 -17.531 -12.771 1.00 51.72 ? 191 GLY B N 1 ATOM 4626 C CA . GLY B 2 159 ? 78.515 -17.702 -12.375 1.00 49.28 ? 191 GLY B CA 1 ATOM 4627 C C . GLY B 2 159 ? 78.066 -16.966 -11.127 1.00 48.03 ? 191 GLY B C 1 ATOM 4628 O O . GLY B 2 159 ? 77.026 -17.302 -10.534 1.00 48.60 ? 191 GLY B O 1 ATOM 4629 N N . PHE B 2 160 ? 78.839 -15.955 -10.734 1.00 47.92 ? 192 PHE B N 1 ATOM 4630 C CA . PHE B 2 160 ? 78.490 -15.077 -9.611 1.00 47.85 ? 192 PHE B CA 1 ATOM 4631 C C . PHE B 2 160 ? 78.534 -13.567 -9.957 1.00 52.00 ? 192 PHE B C 1 ATOM 4632 O O . PHE B 2 160 ? 79.279 -13.126 -10.846 1.00 54.54 ? 192 PHE B O 1 ATOM 4633 C CB . PHE B 2 160 ? 79.391 -15.380 -8.404 1.00 46.33 ? 192 PHE B CB 1 ATOM 4634 C CG . PHE B 2 160 ? 80.872 -15.154 -8.647 1.00 43.73 ? 192 PHE B CG 1 ATOM 4635 C CD1 . PHE B 2 160 ? 81.410 -13.869 -8.695 1.00 43.11 ? 192 PHE B CD1 1 ATOM 4636 C CD2 . PHE B 2 160 ? 81.733 -16.228 -8.773 1.00 42.77 ? 192 PHE B CD2 1 ATOM 4637 C CE1 . PHE B 2 160 ? 82.764 -13.669 -8.887 1.00 43.00 ? 192 PHE B CE1 1 ATOM 4638 C CE2 . PHE B 2 160 ? 83.086 -16.035 -8.966 1.00 42.09 ? 192 PHE B CE2 1 ATOM 4639 C CZ . PHE B 2 160 ? 83.603 -14.759 -9.021 1.00 42.98 ? 192 PHE B CZ 1 ATOM 4640 N N . TYR B 2 161 ? 77.733 -12.778 -9.240 1.00 55.38 ? 193 TYR B N 1 ATOM 4641 C CA . TYR B 2 161 ? 77.699 -11.315 -9.408 1.00 53.59 ? 193 TYR B CA 1 ATOM 4642 C C . TYR B 2 161 ? 77.277 -10.713 -8.069 1.00 49.61 ? 193 TYR B C 1 ATOM 4643 O O . TYR B 2 161 ? 76.938 -11.450 -7.144 1.00 43.31 ? 193 TYR B O 1 ATOM 4644 C CB . TYR B 2 161 ? 76.695 -10.922 -10.508 1.00 53.99 ? 193 TYR B CB 1 ATOM 4645 C CG . TYR B 2 161 ? 75.265 -11.195 -10.090 1.00 54.98 ? 193 TYR B CG 1 ATOM 4646 C CD1 . TYR B 2 161 ? 74.695 -12.451 -10.272 1.00 55.96 ? 193 TYR B CD1 1 ATOM 4647 C CD2 . TYR B 2 161 ? 74.502 -10.210 -9.460 1.00 55.50 ? 193 TYR B CD2 1 ATOM 4648 C CE1 . TYR B 2 161 ? 73.403 -12.711 -9.868 1.00 53.86 ? 193 TYR B CE1 1 ATOM 4649 C CE2 . TYR B 2 161 ? 73.209 -10.459 -9.049 1.00 53.78 ? 193 TYR B CE2 1 ATOM 4650 C CZ . TYR B 2 161 ? 72.670 -11.707 -9.261 1.00 53.92 ? 193 TYR B CZ 1 ATOM 4651 O OH . TYR B 2 161 ? 71.397 -11.945 -8.850 1.00 55.89 ? 193 TYR B OH 1 ATOM 4652 N N . SER B 2 162 ? 77.325 -9.384 -7.975 1.00 49.76 ? 194 SER B N 1 ATOM 4653 C CA . SER B 2 162 ? 76.736 -8.628 -6.851 1.00 50.00 ? 194 SER B CA 1 ATOM 4654 C C . SER B 2 162 ? 76.174 -7.326 -7.350 1.00 45.90 ? 194 SER B C 1 ATOM 4655 O O . SER B 2 162 ? 76.704 -6.729 -8.263 1.00 46.91 ? 194 SER B O 1 ATOM 4656 C CB . SER B 2 162 ? 77.764 -8.281 -5.785 1.00 53.64 ? 194 SER B CB 1 ATOM 4657 O OG . SER B 2 162 ? 78.700 -7.326 -6.269 1.00 53.77 ? 194 SER B OG 1 ATOM 4658 N N . GLN B 2 163 ? 75.124 -6.844 -6.733 1.00 43.69 ? 195 GLN B N 1 ATOM 4659 C CA . GLN B 2 163 ? 74.424 -5.777 -7.369 1.00 46.89 ? 195 GLN B CA 1 ATOM 4660 C C . GLN B 2 163 ? 73.784 -4.924 -6.345 1.00 48.67 ? 195 GLN B C 1 ATOM 4661 O O . GLN B 2 163 ? 73.255 -5.415 -5.375 1.00 51.02 ? 195 GLN B O 1 ATOM 4662 C CB . GLN B 2 163 ? 73.352 -6.354 -8.299 1.00 48.94 ? 195 GLN B CB 1 ATOM 4663 C CG . GLN B 2 163 ? 72.514 -5.317 -9.056 1.00 47.49 ? 195 GLN B CG 1 ATOM 4664 C CD . GLN B 2 163 ? 73.239 -4.705 -10.240 1.00 44.98 ? 195 GLN B CD 1 ATOM 4665 O OE1 . GLN B 2 163 ? 74.225 -5.263 -10.758 1.00 43.19 ? 195 GLN B OE1 1 ATOM 4666 N NE2 . GLN B 2 163 ? 72.741 -3.563 -10.691 1.00 42.70 ? 195 GLN B NE2 1 ATOM 4667 N N . LYS B 2 164 ? 73.815 -3.630 -6.589 1.00 52.34 ? 196 LYS B N 1 ATOM 4668 C CA . LYS B 2 164 ? 73.034 -2.700 -5.813 1.00 53.77 ? 196 LYS B CA 1 ATOM 4669 C C . LYS B 2 164 ? 71.563 -2.790 -6.276 1.00 51.36 ? 196 LYS B C 1 ATOM 4670 O O . LYS B 2 164 ? 71.280 -2.952 -7.477 1.00 52.18 ? 196 LYS B O 1 ATOM 4671 C CB . LYS B 2 164 ? 73.648 -1.306 -5.964 1.00 55.47 ? 196 LYS B CB 1 ATOM 4672 C CG . LYS B 2 164 ? 75.104 -1.281 -5.487 1.00 57.10 ? 196 LYS B CG 1 ATOM 4673 C CD . LYS B 2 164 ? 75.811 0.037 -5.769 1.00 58.43 ? 196 LYS B CD 1 ATOM 4674 C CE . LYS B 2 164 ? 76.658 -0.008 -7.029 1.00 56.51 ? 196 LYS B CE 1 ATOM 4675 N NZ . LYS B 2 164 ? 77.839 0.865 -6.810 1.00 55.40 1 196 LYS B NZ 1 ATOM 4676 N N . VAL B 2 165 ? 70.634 -2.746 -5.324 1.00 46.83 ? 197 VAL B N 1 ATOM 4677 C CA . VAL B 2 165 ? 69.228 -2.804 -5.667 1.00 48.02 ? 197 VAL B CA 1 ATOM 4678 C C . VAL B 2 165 ? 68.874 -1.451 -6.282 1.00 47.72 ? 197 VAL B C 1 ATOM 4679 O O . VAL B 2 165 ? 69.274 -0.412 -5.757 1.00 43.35 ? 197 VAL B O 1 ATOM 4680 C CB . VAL B 2 165 ? 68.328 -3.111 -4.440 1.00 51.32 ? 197 VAL B CB 1 ATOM 4681 C CG1 . VAL B 2 165 ? 66.859 -3.131 -4.847 1.00 52.35 ? 197 VAL B CG1 1 ATOM 4682 C CG2 . VAL B 2 165 ? 68.674 -4.451 -3.809 1.00 51.78 ? 197 VAL B CG2 1 ATOM 4683 N N . THR B 2 166 ? 68.160 -1.467 -7.411 1.00 50.91 ? 198 THR B N 1 ATOM 4684 C CA . THR B 2 166 ? 67.654 -0.220 -8.045 1.00 51.87 ? 198 THR B CA 1 ATOM 4685 C C . THR B 2 166 ? 66.903 0.637 -6.992 1.00 53.99 ? 198 THR B C 1 ATOM 4686 O O . THR B 2 166 ? 67.334 1.746 -6.698 1.00 60.85 ? 198 THR B O 1 ATOM 4687 C CB . THR B 2 166 ? 66.795 -0.493 -9.344 1.00 49.09 ? 198 THR B CB 1 ATOM 4688 O OG1 . THR B 2 166 ? 67.649 -0.595 -10.488 1.00 44.15 ? 198 THR B OG1 1 ATOM 4689 C CG2 . THR B 2 166 ? 65.749 0.601 -9.630 1.00 46.91 ? 198 THR B CG2 1 ATOM 4690 N N . THR B 2 167 ? 65.833 0.110 -6.386 1.00 54.25 ? 199 THR B N 1 ATOM 4691 C CA . THR B 2 167 ? 64.985 0.910 -5.465 1.00 51.10 ? 199 THR B CA 1 ATOM 4692 C C . THR B 2 167 ? 65.485 1.004 -4.028 1.00 44.17 ? 199 THR B C 1 ATOM 4693 O O . THR B 2 167 ? 64.758 1.466 -3.187 1.00 39.58 ? 199 THR B O 1 ATOM 4694 C CB . THR B 2 167 ? 63.509 0.397 -5.361 1.00 54.12 ? 199 THR B CB 1 ATOM 4695 O OG1 . THR B 2 167 ? 63.440 -0.738 -4.479 1.00 57.38 ? 199 THR B OG1 1 ATOM 4696 C CG2 . THR B 2 167 ? 62.883 0.075 -6.757 1.00 53.96 ? 199 THR B CG2 1 ATOM 4697 N N . ASN B 2 168 ? 66.701 0.627 -3.692 1.00 43.36 ? 200 ASN B N 1 ATOM 4698 C CA . ASN B 2 168 ? 67.179 0.697 -2.306 1.00 45.94 ? 200 ASN B CA 1 ATOM 4699 C C . ASN B 2 168 ? 68.647 0.622 -2.547 1.00 48.25 ? 200 ASN B C 1 ATOM 4700 O O . ASN B 2 168 ? 69.300 -0.326 -2.212 1.00 51.23 ? 200 ASN B O 1 ATOM 4701 C CB . ASN B 2 168 ? 66.712 -0.574 -1.584 1.00 47.29 ? 200 ASN B CB 1 ATOM 4702 C CG . ASN B 2 168 ? 65.226 -0.624 -1.331 1.00 48.86 ? 200 ASN B CG 1 ATOM 4703 O OD1 . ASN B 2 168 ? 64.713 -0.042 -0.380 1.00 48.66 ? 200 ASN B OD1 1 ATOM 4704 N ND2 . ASN B 2 168 ? 64.534 -1.367 -2.152 1.00 47.34 ? 200 ASN B ND2 1 ATOM 4705 N N . PRO B 2 169 ? 69.194 1.643 -3.142 1.00 53.28 ? 201 PRO B N 1 ATOM 4706 C CA . PRO B 2 169 ? 70.519 1.520 -3.784 1.00 56.25 ? 201 PRO B CA 1 ATOM 4707 C C . PRO B 2 169 ? 71.748 1.337 -2.891 1.00 57.93 ? 201 PRO B C 1 ATOM 4708 O O . PRO B 2 169 ? 72.855 1.201 -3.434 1.00 58.32 ? 201 PRO B O 1 ATOM 4709 C CB . PRO B 2 169 ? 70.648 2.811 -4.615 1.00 58.77 ? 201 PRO B CB 1 ATOM 4710 C CG . PRO B 2 169 ? 69.293 3.455 -4.598 1.00 58.96 ? 201 PRO B CG 1 ATOM 4711 C CD . PRO B 2 169 ? 68.589 2.967 -3.363 1.00 57.12 ? 201 PRO B CD 1 ATOM 4712 N N . ASN B 2 170 ? 71.572 1.349 -1.564 1.00 59.71 ? 202 ASN B N 1 ATOM 4713 C CA . ASN B 2 170 ? 72.639 0.930 -0.613 1.00 61.58 ? 202 ASN B CA 1 ATOM 4714 C C . ASN B 2 170 ? 72.376 -0.484 -0.023 1.00 63.61 ? 202 ASN B C 1 ATOM 4715 O O . ASN B 2 170 ? 73.002 -0.905 0.964 1.00 62.49 ? 202 ASN B O 1 ATOM 4716 C CB . ASN B 2 170 ? 72.847 1.976 0.494 1.00 58.82 ? 202 ASN B CB 1 ATOM 4717 C CG . ASN B 2 170 ? 71.561 2.339 1.193 1.00 58.09 ? 202 ASN B CG 1 ATOM 4718 O OD1 . ASN B 2 170 ? 70.473 2.248 0.608 1.00 56.10 ? 202 ASN B OD1 1 ATOM 4719 N ND2 . ASN B 2 170 ? 71.669 2.745 2.449 1.00 57.24 ? 202 ASN B ND2 1 ATOM 4720 N N . LEU B 2 171 ? 71.438 -1.199 -0.651 1.00 61.07 ? 203 LEU B N 1 ATOM 4721 C CA . LEU B 2 171 ? 71.249 -2.617 -0.459 1.00 55.47 ? 203 LEU B CA 1 ATOM 4722 C C . LEU B 2 171 ? 71.958 -3.291 -1.620 1.00 53.64 ? 203 LEU B C 1 ATOM 4723 O O . LEU B 2 171 ? 71.577 -3.073 -2.768 1.00 49.47 ? 203 LEU B O 1 ATOM 4724 C CB . LEU B 2 171 ? 69.753 -2.942 -0.493 1.00 55.39 ? 203 LEU B CB 1 ATOM 4725 C CG . LEU B 2 171 ? 69.347 -4.381 -0.153 1.00 56.32 ? 203 LEU B CG 1 ATOM 4726 C CD1 . LEU B 2 171 ? 69.899 -4.778 1.214 1.00 55.13 ? 203 LEU B CD1 1 ATOM 4727 C CD2 . LEU B 2 171 ? 67.834 -4.576 -0.223 1.00 54.38 ? 203 LEU B CD2 1 ATOM 4728 N N . ARG B 2 172 ? 73.005 -4.067 -1.327 1.00 54.91 ? 204 ARG B N 1 ATOM 4729 C CA . ARG B 2 172 ? 73.677 -4.901 -2.342 1.00 57.43 ? 204 ARG B CA 1 ATOM 4730 C C . ARG B 2 172 ? 73.453 -6.414 -2.140 1.00 55.99 ? 204 ARG B C 1 ATOM 4731 O O . ARG B 2 172 ? 74.010 -7.027 -1.229 1.00 60.50 ? 204 ARG B O 1 ATOM 4732 C CB . ARG B 2 172 ? 75.196 -4.654 -2.399 1.00 59.76 ? 204 ARG B CB 1 ATOM 4733 C CG . ARG B 2 172 ? 75.897 -5.534 -3.443 1.00 62.99 ? 204 ARG B CG 1 ATOM 4734 C CD . ARG B 2 172 ? 77.350 -5.888 -3.131 1.00 67.71 ? 204 ARG B CD 1 ATOM 4735 N NE . ARG B 2 172 ? 78.227 -4.755 -2.812 1.00 76.21 ? 204 ARG B NE 1 ATOM 4736 C CZ . ARG B 2 172 ? 78.581 -3.767 -3.645 1.00 79.51 ? 204 ARG B CZ 1 ATOM 4737 N NH1 . ARG B 2 172 ? 78.113 -3.689 -4.891 1.00 77.86 1 204 ARG B NH1 1 ATOM 4738 N NH2 . ARG B 2 172 ? 79.402 -2.815 -3.207 1.00 83.79 ? 204 ARG B NH2 1 ATOM 4739 N N . ILE B 2 173 ? 72.690 -7.022 -3.038 1.00 49.28 ? 205 ILE B N 1 ATOM 4740 C CA . ILE B 2 173 ? 72.572 -8.461 -3.074 1.00 43.55 ? 205 ILE B CA 1 ATOM 4741 C C . ILE B 2 173 ? 73.899 -8.986 -3.552 1.00 40.18 ? 205 ILE B C 1 ATOM 4742 O O . ILE B 2 173 ? 74.349 -8.585 -4.617 1.00 39.86 ? 205 ILE B O 1 ATOM 4743 C CB . ILE B 2 173 ? 71.506 -8.937 -4.085 1.00 44.08 ? 205 ILE B CB 1 ATOM 4744 C CG1 . ILE B 2 173 ? 70.177 -8.171 -3.913 1.00 44.35 ? 205 ILE B CG1 1 ATOM 4745 C CG2 . ILE B 2 173 ? 71.312 -10.445 -3.957 1.00 44.24 ? 205 ILE B CG2 1 ATOM 4746 C CD1 . ILE B 2 173 ? 69.722 -8.019 -2.471 1.00 45.88 ? 205 ILE B CD1 1 ATOM 4747 N N . ILE B 2 174 ? 74.524 -9.865 -2.775 1.00 37.53 ? 206 ILE B N 1 ATOM 4748 C CA . ILE B 2 174 ? 75.586 -10.745 -3.305 1.00 36.78 ? 206 ILE B CA 1 ATOM 4749 C C . ILE B 2 174 ? 75.117 -12.204 -3.627 1.00 38.48 ? 206 ILE B C 1 ATOM 4750 O O . ILE B 2 174 ? 75.162 -13.090 -2.763 1.00 40.59 ? 206 ILE B O 1 ATOM 4751 C CB . ILE B 2 174 ? 76.767 -10.809 -2.342 1.00 34.62 ? 206 ILE B CB 1 ATOM 4752 C CG1 . ILE B 2 174 ? 77.287 -9.410 -2.046 1.00 35.52 ? 206 ILE B CG1 1 ATOM 4753 C CG2 . ILE B 2 174 ? 77.877 -11.672 -2.910 1.00 32.72 ? 206 ILE B CG2 1 ATOM 4754 C CD1 . ILE B 2 174 ? 78.468 -9.422 -1.077 1.00 36.65 ? 206 ILE B CD1 1 ATOM 4755 N N . SER B 2 175 ? 74.689 -12.437 -4.877 1.00 40.80 ? 207 SER B N 1 ATOM 4756 C CA . SER B 2 175 ? 74.355 -13.783 -5.423 1.00 39.79 ? 207 SER B CA 1 ATOM 4757 C C . SER B 2 175 ? 75.605 -14.600 -5.741 1.00 39.46 ? 207 SER B C 1 ATOM 4758 O O . SER B 2 175 ? 76.341 -14.267 -6.692 1.00 33.36 ? 207 SER B O 1 ATOM 4759 C CB . SER B 2 175 ? 73.511 -13.666 -6.708 1.00 40.57 ? 207 SER B CB 1 ATOM 4760 O OG . SER B 2 175 ? 73.769 -14.719 -7.632 1.00 40.74 ? 207 SER B OG 1 ATOM 4761 N N . LEU B 2 176 ? 75.806 -15.670 -4.950 1.00 42.13 ? 208 LEU B N 1 ATOM 4762 C CA . LEU B 2 176 ? 76.950 -16.587 -5.074 1.00 42.44 ? 208 LEU B CA 1 ATOM 4763 C C . LEU B 2 176 ? 76.571 -17.898 -5.740 1.00 44.84 ? 208 LEU B C 1 ATOM 4764 O O . LEU B 2 176 ? 75.406 -18.339 -5.761 1.00 48.71 ? 208 LEU B O 1 ATOM 4765 C CB . LEU B 2 176 ? 77.529 -16.948 -3.708 1.00 43.42 ? 208 LEU B CB 1 ATOM 4766 C CG . LEU B 2 176 ? 78.246 -15.918 -2.820 1.00 45.72 ? 208 LEU B CG 1 ATOM 4767 C CD1 . LEU B 2 176 ? 78.230 -16.418 -1.386 1.00 46.70 ? 208 LEU B CD1 1 ATOM 4768 C CD2 . LEU B 2 176 ? 79.684 -15.628 -3.240 1.00 46.36 ? 208 LEU B CD2 1 ATOM 4769 N N . ASN B 2 177 ? 77.606 -18.517 -6.279 1.00 47.33 ? 209 ASN B N 1 ATOM 4770 C CA . ASN B 2 177 ? 77.541 -19.843 -6.871 1.00 48.86 ? 209 ASN B CA 1 ATOM 4771 C C . ASN B 2 177 ? 78.193 -20.801 -5.902 1.00 47.00 ? 209 ASN B C 1 ATOM 4772 O O . ASN B 2 177 ? 79.422 -21.005 -5.937 1.00 48.19 ? 209 ASN B O 1 ATOM 4773 C CB . ASN B 2 177 ? 78.295 -19.857 -8.206 1.00 51.12 ? 209 ASN B CB 1 ATOM 4774 C CG . ASN B 2 177 ? 78.356 -21.233 -8.850 1.00 52.07 ? 209 ASN B CG 1 ATOM 4775 O OD1 . ASN B 2 177 ? 78.431 -22.269 -8.173 1.00 53.41 ? 209 ASN B OD1 1 ATOM 4776 N ND2 . ASN B 2 177 ? 78.350 -21.246 -10.178 1.00 54.37 ? 209 ASN B ND2 1 ATOM 4777 N N . THR B 2 178 ? 77.367 -21.378 -5.038 1.00 41.35 ? 210 THR B N 1 ATOM 4778 C CA . THR B 2 178 ? 77.839 -22.313 -4.050 1.00 38.63 ? 210 THR B CA 1 ATOM 4779 C C . THR B 2 178 ? 77.787 -23.727 -4.599 1.00 38.15 ? 210 THR B C 1 ATOM 4780 O O . THR B 2 178 ? 78.134 -24.693 -3.903 1.00 38.86 ? 210 THR B O 1 ATOM 4781 C CB . THR B 2 178 ? 76.975 -22.194 -2.820 1.00 38.03 ? 210 THR B CB 1 ATOM 4782 O OG1 . THR B 2 178 ? 75.622 -22.005 -3.252 1.00 36.55 ? 210 THR B OG1 1 ATOM 4783 C CG2 . THR B 2 178 ? 77.437 -21.006 -2.012 1.00 37.54 ? 210 THR B CG2 1 ATOM 4784 N N . ASN B 2 179 ? 77.368 -23.835 -5.856 1.00 35.23 ? 211 ASN B N 1 ATOM 4785 C CA . ASN B 2 179 ? 77.511 -25.057 -6.610 1.00 35.92 ? 211 ASN B CA 1 ATOM 4786 C C . ASN B 2 179 ? 78.982 -25.385 -6.912 1.00 38.42 ? 211 ASN B C 1 ATOM 4787 O O . ASN B 2 179 ? 79.316 -26.531 -7.210 1.00 39.07 ? 211 ASN B O 1 ATOM 4788 C CB . ASN B 2 179 ? 76.720 -24.955 -7.909 1.00 35.29 ? 211 ASN B CB 1 ATOM 4789 C CG . ASN B 2 179 ? 75.300 -24.461 -7.695 1.00 33.92 ? 211 ASN B CG 1 ATOM 4790 O OD1 . ASN B 2 179 ? 74.876 -23.488 -8.293 1.00 34.18 ? 211 ASN B OD1 1 ATOM 4791 N ND2 . ASN B 2 179 ? 74.566 -25.132 -6.852 1.00 33.67 ? 211 ASN B ND2 1 ATOM 4792 N N . LEU B 2 180 ? 79.853 -24.380 -6.827 1.00 41.04 ? 212 LEU B N 1 ATOM 4793 C CA . LEU B 2 180 ? 81.330 -24.572 -6.889 1.00 45.44 ? 212 LEU B CA 1 ATOM 4794 C C . LEU B 2 180 ? 81.908 -25.369 -5.693 1.00 44.95 ? 212 LEU B C 1 ATOM 4795 O O . LEU B 2 180 ? 82.932 -26.050 -5.816 1.00 47.58 ? 212 LEU B O 1 ATOM 4796 C CB . LEU B 2 180 ? 82.056 -23.205 -6.988 1.00 47.43 ? 212 LEU B CB 1 ATOM 4797 C CG . LEU B 2 180 ? 81.631 -22.264 -8.148 1.00 47.67 ? 212 LEU B CG 1 ATOM 4798 C CD1 . LEU B 2 180 ? 82.048 -20.813 -7.907 1.00 45.60 ? 212 LEU B CD1 1 ATOM 4799 C CD2 . LEU B 2 180 ? 82.108 -22.779 -9.514 1.00 46.95 ? 212 LEU B CD2 1 ATOM 4800 N N . TYR B 2 181 ? 81.236 -25.275 -4.547 1.00 42.95 ? 213 TYR B N 1 ATOM 4801 C CA . TYR B 2 181 ? 81.642 -25.948 -3.330 1.00 39.50 ? 213 TYR B CA 1 ATOM 4802 C C . TYR B 2 181 ? 80.848 -27.206 -3.034 1.00 37.96 ? 213 TYR B C 1 ATOM 4803 O O . TYR B 2 181 ? 81.035 -27.799 -1.985 1.00 34.65 ? 213 TYR B O 1 ATOM 4804 C CB . TYR B 2 181 ? 81.460 -24.989 -2.185 1.00 41.25 ? 213 TYR B CB 1 ATOM 4805 C CG . TYR B 2 181 ? 82.044 -23.641 -2.476 1.00 45.53 ? 213 TYR B CG 1 ATOM 4806 C CD1 . TYR B 2 181 ? 83.327 -23.512 -3.018 1.00 44.34 ? 213 TYR B CD1 1 ATOM 4807 C CD2 . TYR B 2 181 ? 81.308 -22.479 -2.215 1.00 48.42 ? 213 TYR B CD2 1 ATOM 4808 C CE1 . TYR B 2 181 ? 83.846 -22.262 -3.290 1.00 47.30 ? 213 TYR B CE1 1 ATOM 4809 C CE2 . TYR B 2 181 ? 81.830 -21.221 -2.475 1.00 48.34 ? 213 TYR B CE2 1 ATOM 4810 C CZ . TYR B 2 181 ? 83.087 -21.124 -3.017 1.00 48.65 ? 213 TYR B CZ 1 ATOM 4811 O OH . TYR B 2 181 ? 83.578 -19.880 -3.270 1.00 50.59 ? 213 TYR B OH 1 ATOM 4812 N N . TYR B 2 182 ? 79.970 -27.613 -3.953 1.00 39.69 ? 214 TYR B N 1 ATOM 4813 C CA . TYR B 2 182 ? 79.093 -28.782 -3.770 1.00 38.85 ? 214 TYR B CA 1 ATOM 4814 C C . TYR B 2 182 ? 79.818 -30.094 -3.979 1.00 41.11 ? 214 TYR B C 1 ATOM 4815 O O . TYR B 2 182 ? 80.573 -30.251 -4.950 1.00 44.68 ? 214 TYR B O 1 ATOM 4816 C CB . TYR B 2 182 ? 77.960 -28.714 -4.771 1.00 38.05 ? 214 TYR B CB 1 ATOM 4817 C CG . TYR B 2 182 ? 76.922 -29.784 -4.630 1.00 38.05 ? 214 TYR B CG 1 ATOM 4818 C CD1 . TYR B 2 182 ? 76.581 -30.315 -3.380 1.00 38.73 ? 214 TYR B CD1 1 ATOM 4819 C CD2 . TYR B 2 182 ? 76.237 -30.235 -5.748 1.00 38.42 ? 214 TYR B CD2 1 ATOM 4820 C CE1 . TYR B 2 182 ? 75.607 -31.285 -3.261 1.00 39.35 ? 214 TYR B CE1 1 ATOM 4821 C CE2 . TYR B 2 182 ? 75.261 -31.198 -5.644 1.00 40.16 ? 214 TYR B CE2 1 ATOM 4822 C CZ . TYR B 2 182 ? 74.949 -31.710 -4.402 1.00 40.68 ? 214 TYR B CZ 1 ATOM 4823 O OH . TYR B 2 182 ? 73.970 -32.647 -4.339 1.00 42.11 ? 214 TYR B OH 1 ATOM 4824 N N . GLY B 2 183 ? 79.582 -31.042 -3.080 1.00 41.96 ? 215 GLY B N 1 ATOM 4825 C CA . GLY B 2 183 ? 80.294 -32.320 -3.101 1.00 41.49 ? 215 GLY B CA 1 ATOM 4826 C C . GLY B 2 183 ? 80.536 -32.873 -4.488 1.00 39.81 ? 215 GLY B C 1 ATOM 4827 O O . GLY B 2 183 ? 81.669 -32.851 -4.958 1.00 37.90 ? 215 GLY B O 1 ATOM 4828 N N . PRO B 2 184 ? 79.465 -33.333 -5.165 1.00 42.26 ? 216 PRO B N 1 ATOM 4829 C CA . PRO B 2 184 ? 79.496 -33.952 -6.515 1.00 43.36 ? 216 PRO B CA 1 ATOM 4830 C C . PRO B 2 184 ? 80.179 -33.175 -7.664 1.00 43.82 ? 216 PRO B C 1 ATOM 4831 O O . PRO B 2 184 ? 80.398 -33.769 -8.736 1.00 42.51 ? 216 PRO B O 1 ATOM 4832 C CB . PRO B 2 184 ? 78.011 -34.140 -6.852 1.00 42.51 ? 216 PRO B CB 1 ATOM 4833 C CG . PRO B 2 184 ? 77.341 -34.235 -5.526 1.00 43.31 ? 216 PRO B CG 1 ATOM 4834 C CD . PRO B 2 184 ? 78.094 -33.309 -4.616 1.00 43.23 ? 216 PRO B CD 1 ATOM 4835 N N . ASN B 2 185 ? 80.506 -31.889 -7.451 1.00 43.67 ? 217 ASN B N 1 ATOM 4836 C CA . ASN B 2 185 ? 81.168 -31.062 -8.466 1.00 43.51 ? 217 ASN B CA 1 ATOM 4837 C C . ASN B 2 185 ? 82.616 -31.472 -8.700 1.00 45.64 ? 217 ASN B C 1 ATOM 4838 O O . ASN B 2 185 ? 83.491 -31.134 -7.900 1.00 46.47 ? 217 ASN B O 1 ATOM 4839 C CB . ASN B 2 185 ? 81.122 -29.593 -8.062 1.00 42.92 ? 217 ASN B CB 1 ATOM 4840 C CG . ASN B 2 185 ? 81.520 -28.659 -9.195 1.00 44.30 ? 217 ASN B CG 1 ATOM 4841 O OD1 . ASN B 2 185 ? 81.872 -29.088 -10.297 1.00 42.20 ? 217 ASN B OD1 1 ATOM 4842 N ND2 . ASN B 2 185 ? 81.438 -27.364 -8.930 1.00 46.98 ? 217 ASN B ND2 1 ATOM 4843 N N . ILE B 2 186 ? 82.859 -32.189 -9.803 1.00 47.47 ? 218 ILE B N 1 ATOM 4844 C CA . ILE B 2 186 ? 84.191 -32.751 -10.110 1.00 47.51 ? 218 ILE B CA 1 ATOM 4845 C C . ILE B 2 186 ? 85.193 -31.694 -10.599 1.00 46.94 ? 218 ILE B C 1 ATOM 4846 O O . ILE B 2 186 ? 86.396 -31.844 -10.382 1.00 42.23 ? 218 ILE B O 1 ATOM 4847 C CB . ILE B 2 186 ? 84.107 -33.892 -11.155 1.00 47.15 ? 218 ILE B CB 1 ATOM 4848 C CG1 . ILE B 2 186 ? 83.265 -35.068 -10.639 1.00 46.85 ? 218 ILE B CG1 1 ATOM 4849 C CG2 . ILE B 2 186 ? 85.498 -34.373 -11.553 1.00 47.19 ? 218 ILE B CG2 1 ATOM 4850 C CD1 . ILE B 2 186 ? 83.940 -35.948 -9.603 1.00 48.59 ? 218 ILE B CD1 1 ATOM 4851 N N . MET B 2 187 ? 84.706 -30.638 -11.254 1.00 50.25 ? 219 MET B N 1 ATOM 4852 C CA . MET B 2 187 ? 85.571 -29.519 -11.677 1.00 55.35 ? 219 MET B CA 1 ATOM 4853 C C . MET B 2 187 ? 86.372 -28.888 -10.535 1.00 54.47 ? 219 MET B C 1 ATOM 4854 O O . MET B 2 187 ? 87.534 -28.573 -10.733 1.00 54.01 ? 219 MET B O 1 ATOM 4855 C CB . MET B 2 187 ? 84.767 -28.407 -12.382 1.00 59.14 ? 219 MET B CB 1 ATOM 4856 C CG . MET B 2 187 ? 84.154 -28.789 -13.728 1.00 62.73 ? 219 MET B CG 1 ATOM 4857 S SD . MET B 2 187 ? 85.131 -29.920 -14.760 1.00 64.37 ? 219 MET B SD 1 ATOM 4858 C CE . MET B 2 187 ? 84.488 -31.532 -14.287 1.00 57.34 ? 219 MET B CE 1 ATOM 4859 N N . THR B 2 188 ? 85.757 -28.718 -9.356 1.00 55.52 ? 220 THR B N 1 ATOM 4860 C CA . THR B 2 188 ? 86.373 -27.991 -8.223 1.00 53.43 ? 220 THR B CA 1 ATOM 4861 C C . THR B 2 188 ? 87.072 -28.863 -7.164 1.00 51.69 ? 220 THR B C 1 ATOM 4862 O O . THR B 2 188 ? 87.476 -28.346 -6.125 1.00 51.48 ? 220 THR B O 1 ATOM 4863 C CB . THR B 2 188 ? 85.356 -27.045 -7.504 1.00 54.05 ? 220 THR B CB 1 ATOM 4864 O OG1 . THR B 2 188 ? 84.314 -27.809 -6.868 1.00 51.54 ? 220 THR B OG1 1 ATOM 4865 C CG2 . THR B 2 188 ? 84.753 -26.016 -8.496 1.00 52.61 ? 220 THR B CG2 1 ATOM 4866 N N . LEU B 2 189 ? 87.225 -30.164 -7.419 1.00 52.18 ? 221 LEU B N 1 ATOM 4867 C CA . LEU B 2 189 ? 88.035 -31.042 -6.538 1.00 54.35 ? 221 LEU B CA 1 ATOM 4868 C C . LEU B 2 189 ? 89.453 -30.512 -6.265 1.00 60.87 ? 221 LEU B C 1 ATOM 4869 O O . LEU B 2 189 ? 90.123 -29.975 -7.153 1.00 65.29 ? 221 LEU B O 1 ATOM 4870 C CB . LEU B 2 189 ? 88.151 -32.469 -7.096 1.00 49.16 ? 221 LEU B CB 1 ATOM 4871 C CG . LEU B 2 189 ? 87.250 -33.490 -6.408 1.00 46.41 ? 221 LEU B CG 1 ATOM 4872 C CD1 . LEU B 2 189 ? 86.888 -34.632 -7.349 1.00 46.80 ? 221 LEU B CD1 1 ATOM 4873 C CD2 . LEU B 2 189 ? 87.919 -34.017 -5.151 1.00 44.17 ? 221 LEU B CD2 1 ATOM 4874 N N . ASN B 2 190 ? 89.890 -30.661 -5.016 1.00 64.51 ? 222 ASN B N 1 ATOM 4875 C CA . ASN B 2 190 ? 91.227 -30.279 -4.591 1.00 63.46 ? 222 ASN B CA 1 ATOM 4876 C C . ASN B 2 190 ? 91.607 -28.821 -4.877 1.00 60.72 ? 222 ASN B C 1 ATOM 4877 O O . ASN B 2 190 ? 92.776 -28.484 -4.769 1.00 59.77 ? 222 ASN B O 1 ATOM 4878 C CB . ASN B 2 190 ? 92.249 -31.228 -5.227 1.00 67.26 ? 222 ASN B CB 1 ATOM 4879 C CG . ASN B 2 190 ? 93.218 -31.801 -4.215 1.00 74.92 ? 222 ASN B CG 1 ATOM 4880 O OD1 . ASN B 2 190 ? 92.821 -32.189 -3.107 1.00 78.19 ? 222 ASN B OD1 1 ATOM 4881 N ND2 . ASN B 2 190 ? 94.495 -31.874 -4.590 1.00 77.77 ? 222 ASN B ND2 1 ATOM 4882 N N . LYS B 2 191 ? 90.629 -27.968 -5.213 1.00 60.81 ? 223 LYS B N 1 ATOM 4883 C CA . LYS B 2 191 ? 90.867 -26.540 -5.482 1.00 62.36 ? 223 LYS B CA 1 ATOM 4884 C C . LYS B 2 191 ? 90.745 -25.672 -4.209 1.00 64.79 ? 223 LYS B C 1 ATOM 4885 O O . LYS B 2 191 ? 89.677 -25.545 -3.617 1.00 61.34 ? 223 LYS B O 1 ATOM 4886 C CB . LYS B 2 191 ? 89.911 -26.000 -6.566 1.00 61.68 ? 223 LYS B CB 1 ATOM 4887 C CG . LYS B 2 191 ? 90.268 -26.364 -8.001 1.00 61.83 ? 223 LYS B CG 1 ATOM 4888 C CD . LYS B 2 191 ? 90.228 -25.140 -8.918 1.00 64.64 ? 223 LYS B CD 1 ATOM 4889 C CE . LYS B 2 191 ? 90.560 -25.492 -10.370 1.00 67.23 ? 223 LYS B CE 1 ATOM 4890 N NZ . LYS B 2 191 ? 91.044 -24.331 -11.183 1.00 67.93 1 223 LYS B NZ 1 ATOM 4891 N N . THR B 2 192 ? 91.867 -25.087 -3.807 1.00 71.09 ? 224 THR B N 1 ATOM 4892 C CA . THR B 2 192 ? 91.946 -24.102 -2.722 1.00 72.73 ? 224 THR B CA 1 ATOM 4893 C C . THR B 2 192 ? 90.851 -22.992 -2.728 1.00 71.99 ? 224 THR B C 1 ATOM 4894 O O . THR B 2 192 ? 90.288 -22.656 -1.679 1.00 64.38 ? 224 THR B O 1 ATOM 4895 C CB . THR B 2 192 ? 93.360 -23.456 -2.735 1.00 75.98 ? 224 THR B CB 1 ATOM 4896 O OG1 . THR B 2 192 ? 93.481 -22.554 -1.637 1.00 80.38 ? 224 THR B OG1 1 ATOM 4897 C CG2 . THR B 2 192 ? 93.676 -22.705 -4.094 1.00 75.02 ? 224 THR B CG2 1 ATOM 4898 N N . ASP B 2 193 ? 90.555 -22.433 -3.903 1.00 71.63 ? 225 ASP B N 1 ATOM 4899 C CA . ASP B 2 193 ? 89.572 -21.352 -4.034 1.00 70.68 ? 225 ASP B CA 1 ATOM 4900 C C . ASP B 2 193 ? 89.026 -21.315 -5.471 1.00 69.83 ? 225 ASP B C 1 ATOM 4901 O O . ASP B 2 193 ? 89.592 -20.640 -6.342 1.00 72.49 ? 225 ASP B O 1 ATOM 4902 C CB . ASP B 2 193 ? 90.193 -19.998 -3.643 1.00 69.79 ? 225 ASP B CB 1 ATOM 4903 C CG . ASP B 2 193 ? 89.221 -18.821 -3.808 1.00 71.78 ? 225 ASP B CG 1 ATOM 4904 O OD1 . ASP B 2 193 ? 87.985 -19.040 -3.926 1.00 81.08 ? 225 ASP B OD1 1 ATOM 4905 O OD2 . ASP B 2 193 ? 89.700 -17.668 -3.816 1.00 63.95 -1 225 ASP B OD2 1 ATOM 4906 N N . PRO B 2 194 ? 87.918 -22.037 -5.721 1.00 64.82 ? 226 PRO B N 1 ATOM 4907 C CA . PRO B 2 194 ? 87.386 -22.139 -7.078 1.00 62.26 ? 226 PRO B CA 1 ATOM 4908 C C . PRO B 2 194 ? 86.948 -20.787 -7.621 1.00 55.70 ? 226 PRO B C 1 ATOM 4909 O O . PRO B 2 194 ? 86.460 -19.971 -6.850 1.00 65.57 ? 226 PRO B O 1 ATOM 4910 C CB . PRO B 2 194 ? 86.179 -23.088 -6.939 1.00 64.22 ? 226 PRO B CB 1 ATOM 4911 C CG . PRO B 2 194 ? 86.248 -23.677 -5.583 1.00 65.12 ? 226 PRO B CG 1 ATOM 4912 C CD . PRO B 2 194 ? 87.118 -22.787 -4.743 1.00 65.93 ? 226 PRO B CD 1 ATOM 4913 N N . ALA B 2 195 ? 87.152 -20.572 -8.922 1.00 47.26 ? 227 ALA B N 1 ATOM 4914 C CA . ALA B 2 195 ? 86.800 -19.338 -9.649 1.00 43.22 ? 227 ALA B CA 1 ATOM 4915 C C . ALA B 2 195 ? 87.025 -18.048 -8.868 1.00 44.71 ? 227 ALA B C 1 ATOM 4916 O O . ALA B 2 195 ? 86.302 -17.074 -9.089 1.00 38.68 ? 227 ALA B O 1 ATOM 4917 C CB . ALA B 2 195 ? 85.340 -19.355 -9.996 1.00 42.26 ? 227 ALA B CB 1 ATOM 4918 N N . ASN B 2 196 ? 88.074 -18.041 -8.027 1.00 51.41 ? 228 ASN B N 1 ATOM 4919 C CA . ASN B 2 196 ? 88.385 -16.975 -7.043 1.00 56.55 ? 228 ASN B CA 1 ATOM 4920 C C . ASN B 2 196 ? 87.182 -16.250 -6.412 1.00 56.49 ? 228 ASN B C 1 ATOM 4921 O O . ASN B 2 196 ? 86.998 -15.046 -6.553 1.00 58.10 ? 228 ASN B O 1 ATOM 4922 C CB . ASN B 2 196 ? 89.345 -15.995 -7.736 1.00 60.09 ? 228 ASN B CB 1 ATOM 4923 C CG . ASN B 2 196 ? 90.641 -16.661 -8.172 1.00 62.12 ? 228 ASN B CG 1 ATOM 4924 O OD1 . ASN B 2 196 ? 91.107 -17.632 -7.553 1.00 60.43 ? 228 ASN B OD1 1 ATOM 4925 N ND2 . ASN B 2 196 ? 91.226 -16.152 -9.253 1.00 64.57 ? 228 ASN B ND2 1 ATOM 4926 N N . GLN B 2 197 ? 86.387 -17.013 -5.681 1.00 57.56 ? 229 GLN B N 1 ATOM 4927 C CA . GLN B 2 197 ? 85.116 -16.543 -5.184 1.00 57.36 ? 229 GLN B CA 1 ATOM 4928 C C . GLN B 2 197 ? 85.220 -16.013 -3.777 1.00 59.17 ? 229 GLN B C 1 ATOM 4929 O O . GLN B 2 197 ? 84.496 -15.081 -3.402 1.00 58.55 ? 229 GLN B O 1 ATOM 4930 C CB . GLN B 2 197 ? 84.121 -17.691 -5.202 1.00 57.53 ? 229 GLN B CB 1 ATOM 4931 C CG . GLN B 2 197 ? 82.763 -17.326 -4.620 1.00 57.01 ? 229 GLN B CG 1 ATOM 4932 C CD . GLN B 2 197 ? 81.655 -18.200 -5.151 1.00 53.27 ? 229 GLN B CD 1 ATOM 4933 O OE1 . GLN B 2 197 ? 81.566 -19.384 -4.815 1.00 50.64 ? 229 GLN B OE1 1 ATOM 4934 N NE2 . GLN B 2 197 ? 80.799 -17.619 -5.989 1.00 49.46 ? 229 GLN B NE2 1 ATOM 4935 N N . PHE B 2 198 ? 86.079 -16.639 -2.981 1.00 61.60 ? 230 PHE B N 1 ATOM 4936 C CA . PHE B 2 198 ? 86.264 -16.208 -1.607 1.00 66.85 ? 230 PHE B CA 1 ATOM 4937 C C . PHE B 2 198 ? 86.987 -14.857 -1.606 1.00 71.69 ? 230 PHE B C 1 ATOM 4938 O O . PHE B 2 198 ? 86.646 -13.956 -0.822 1.00 74.75 ? 230 PHE B O 1 ATOM 4939 C CB . PHE B 2 198 ? 87.045 -17.256 -0.807 1.00 66.40 ? 230 PHE B CB 1 ATOM 4940 C CG . PHE B 2 198 ? 86.399 -18.609 -0.787 1.00 65.75 ? 230 PHE B CG 1 ATOM 4941 C CD1 . PHE B 2 198 ? 85.063 -18.748 -0.443 1.00 67.07 ? 230 PHE B CD1 1 ATOM 4942 C CD2 . PHE B 2 198 ? 87.132 -19.749 -1.103 1.00 67.05 ? 230 PHE B CD2 1 ATOM 4943 C CE1 . PHE B 2 198 ? 84.468 -19.994 -0.426 1.00 68.45 ? 230 PHE B CE1 1 ATOM 4944 C CE2 . PHE B 2 198 ? 86.542 -20.999 -1.092 1.00 67.94 ? 230 PHE B CE2 1 ATOM 4945 C CZ . PHE B 2 198 ? 85.209 -21.122 -0.745 1.00 69.01 ? 230 PHE B CZ 1 ATOM 4946 N N . GLU B 2 199 ? 87.970 -14.732 -2.502 1.00 70.04 ? 231 GLU B N 1 ATOM 4947 C CA . GLU B 2 199 ? 88.716 -13.491 -2.719 1.00 71.50 ? 231 GLU B CA 1 ATOM 4948 C C . GLU B 2 199 ? 87.774 -12.335 -3.070 1.00 68.52 ? 231 GLU B C 1 ATOM 4949 O O . GLU B 2 199 ? 87.861 -11.251 -2.502 1.00 65.85 ? 231 GLU B O 1 ATOM 4950 C CB . GLU B 2 199 ? 89.712 -13.712 -3.858 1.00 79.82 ? 231 GLU B CB 1 ATOM 4951 C CG . GLU B 2 199 ? 90.740 -12.614 -4.073 1.00 86.27 ? 231 GLU B CG 1 ATOM 4952 C CD . GLU B 2 199 ? 91.687 -12.931 -5.227 1.00 91.17 ? 231 GLU B CD 1 ATOM 4953 O OE1 . GLU B 2 199 ? 91.377 -13.835 -6.044 1.00 87.79 ? 231 GLU B OE1 1 ATOM 4954 O OE2 . GLU B 2 199 ? 92.753 -12.276 -5.317 1.00 95.18 -1 231 GLU B OE2 1 ATOM 4955 N N . TRP B 2 200 ? 86.870 -12.595 -4.007 1.00 67.26 ? 232 TRP B N 1 ATOM 4956 C CA . TRP B 2 200 ? 85.856 -11.627 -4.446 1.00 66.86 ? 232 TRP B CA 1 ATOM 4957 C C . TRP B 2 200 ? 84.741 -11.376 -3.401 1.00 63.86 ? 232 TRP B C 1 ATOM 4958 O O . TRP B 2 200 ? 84.188 -10.270 -3.328 1.00 58.95 ? 232 TRP B O 1 ATOM 4959 C CB . TRP B 2 200 ? 85.247 -12.115 -5.770 1.00 69.13 ? 232 TRP B CB 1 ATOM 4960 C CG . TRP B 2 200 ? 84.317 -11.148 -6.429 1.00 68.51 ? 232 TRP B CG 1 ATOM 4961 C CD1 . TRP B 2 200 ? 84.644 -10.149 -7.306 1.00 73.18 ? 232 TRP B CD1 1 ATOM 4962 C CD2 . TRP B 2 200 ? 82.906 -11.098 -6.273 1.00 63.56 ? 232 TRP B CD2 1 ATOM 4963 N NE1 . TRP B 2 200 ? 83.510 -9.473 -7.694 1.00 72.19 ? 232 TRP B NE1 1 ATOM 4964 C CE2 . TRP B 2 200 ? 82.431 -10.036 -7.069 1.00 64.82 ? 232 TRP B CE2 1 ATOM 4965 C CE3 . TRP B 2 200 ? 81.995 -11.846 -5.531 1.00 62.67 ? 232 TRP B CE3 1 ATOM 4966 C CZ2 . TRP B 2 200 ? 81.091 -9.709 -7.145 1.00 62.22 ? 232 TRP B CZ2 1 ATOM 4967 C CZ3 . TRP B 2 200 ? 80.665 -11.524 -5.612 1.00 62.11 ? 232 TRP B CZ3 1 ATOM 4968 C CH2 . TRP B 2 200 ? 80.225 -10.466 -6.413 1.00 61.71 ? 232 TRP B CH2 1 ATOM 4969 N N . LEU B 2 201 ? 84.407 -12.405 -2.618 1.00 62.61 ? 233 LEU B N 1 ATOM 4970 C CA . LEU B 2 201 ? 83.468 -12.273 -1.495 1.00 61.13 ? 233 LEU B CA 1 ATOM 4971 C C . LEU B 2 201 ? 84.047 -11.330 -0.435 1.00 60.37 ? 233 LEU B C 1 ATOM 4972 O O . LEU B 2 201 ? 83.439 -10.300 -0.103 1.00 53.82 ? 233 LEU B O 1 ATOM 4973 C CB . LEU B 2 201 ? 83.156 -13.652 -0.881 1.00 59.33 ? 233 LEU B CB 1 ATOM 4974 C CG . LEU B 2 201 ? 82.171 -13.699 0.293 1.00 55.07 ? 233 LEU B CG 1 ATOM 4975 C CD1 . LEU B 2 201 ? 80.829 -13.128 -0.112 1.00 53.78 ? 233 LEU B CD1 1 ATOM 4976 C CD2 . LEU B 2 201 ? 82.015 -15.132 0.735 1.00 54.91 ? 233 LEU B CD2 1 ATOM 4977 N N . GLU B 2 202 ? 85.228 -11.696 0.072 1.00 59.83 ? 234 GLU B N 1 ATOM 4978 C CA . GLU B 2 202 ? 85.998 -10.844 0.970 1.00 62.48 ? 234 GLU B CA 1 ATOM 4979 C C . GLU B 2 202 ? 86.135 -9.425 0.409 1.00 65.46 ? 234 GLU B C 1 ATOM 4980 O O . GLU B 2 202 ? 85.887 -8.450 1.125 1.00 65.96 ? 234 GLU B O 1 ATOM 4981 C CB . GLU B 2 202 ? 87.380 -11.458 1.243 1.00 63.63 ? 234 GLU B CB 1 ATOM 4982 C CG . GLU B 2 202 ? 87.423 -12.328 2.494 1.00 67.84 ? 234 GLU B CG 1 ATOM 4983 C CD . GLU B 2 202 ? 88.494 -13.409 2.470 1.00 69.13 ? 234 GLU B CD 1 ATOM 4984 O OE1 . GLU B 2 202 ? 88.858 -13.879 1.365 1.00 62.13 ? 234 GLU B OE1 1 ATOM 4985 O OE2 . GLU B 2 202 ? 88.947 -13.803 3.574 1.00 71.68 -1 234 GLU B OE2 1 ATOM 4986 N N . SER B 2 203 ? 86.515 -9.332 -0.871 1.00 68.27 ? 235 SER B N 1 ATOM 4987 C CA . SER B 2 203 ? 86.647 -8.050 -1.603 1.00 69.11 ? 235 SER B CA 1 ATOM 4988 C C . SER B 2 203 ? 85.349 -7.226 -1.638 1.00 72.81 ? 235 SER B C 1 ATOM 4989 O O . SER B 2 203 ? 85.367 -6.025 -1.335 1.00 73.50 ? 235 SER B O 1 ATOM 4990 C CB . SER B 2 203 ? 87.136 -8.308 -3.046 1.00 65.55 ? 235 SER B CB 1 ATOM 4991 O OG . SER B 2 203 ? 87.183 -7.126 -3.831 1.00 59.60 ? 235 SER B OG 1 ATOM 4992 N N . THR B 2 204 ? 84.238 -7.868 -2.005 1.00 74.93 ? 236 THR B N 1 ATOM 4993 C CA . THR B 2 204 ? 82.946 -7.181 -2.130 1.00 79.18 ? 236 THR B CA 1 ATOM 4994 C C . THR B 2 204 ? 82.338 -6.794 -0.774 1.00 88.16 ? 236 THR B C 1 ATOM 4995 O O . THR B 2 204 ? 81.685 -5.750 -0.659 1.00 91.42 ? 236 THR B O 1 ATOM 4996 C CB . THR B 2 204 ? 81.918 -8.034 -2.900 1.00 76.85 ? 236 THR B CB 1 ATOM 4997 O OG1 . THR B 2 204 ? 82.524 -8.565 -4.086 1.00 78.91 ? 236 THR B OG1 1 ATOM 4998 C CG2 . THR B 2 204 ? 80.683 -7.190 -3.277 1.00 71.41 ? 236 THR B CG2 1 ATOM 4999 N N . LEU B 2 205 ? 82.533 -7.640 0.240 1.00 91.81 ? 237 LEU B N 1 ATOM 5000 C CA . LEU B 2 205 ? 82.029 -7.357 1.591 1.00 86.52 ? 237 LEU B CA 1 ATOM 5001 C C . LEU B 2 205 ? 82.819 -6.209 2.218 1.00 84.88 ? 237 LEU B C 1 ATOM 5002 O O . LEU B 2 205 ? 82.226 -5.214 2.643 1.00 84.68 ? 237 LEU B O 1 ATOM 5003 C CB . LEU B 2 205 ? 82.081 -8.615 2.470 1.00 83.13 ? 237 LEU B CB 1 ATOM 5004 C CG . LEU B 2 205 ? 81.097 -9.727 2.075 1.00 76.28 ? 237 LEU B CG 1 ATOM 5005 C CD1 . LEU B 2 205 ? 81.463 -11.038 2.764 1.00 74.32 ? 237 LEU B CD1 1 ATOM 5006 C CD2 . LEU B 2 205 ? 79.661 -9.312 2.371 1.00 70.79 ? 237 LEU B CD2 1 ATOM 5007 N N . ASN B 2 206 ? 84.147 -6.350 2.250 1.00 81.56 ? 238 ASN B N 1 ATOM 5008 C CA . ASN B 2 206 ? 85.061 -5.266 2.650 1.00 77.73 ? 238 ASN B CA 1 ATOM 5009 C C . ASN B 2 206 ? 84.661 -3.923 2.021 1.00 76.06 ? 238 ASN B C 1 ATOM 5010 O O . ASN B 2 206 ? 84.527 -2.909 2.725 1.00 73.32 ? 238 ASN B O 1 ATOM 5011 C CB . ASN B 2 206 ? 86.509 -5.635 2.283 1.00 76.98 ? 238 ASN B CB 1 ATOM 5012 C CG . ASN B 2 206 ? 87.544 -4.799 3.026 1.00 78.32 ? 238 ASN B CG 1 ATOM 5013 O OD1 . ASN B 2 206 ? 87.469 -3.572 3.046 1.00 77.87 ? 238 ASN B OD1 1 ATOM 5014 N ND2 . ASN B 2 206 ? 88.524 -5.463 3.632 1.00 76.81 ? 238 ASN B ND2 1 ATOM 5015 N N . ASN B 2 207 ? 84.449 -3.943 0.702 1.00 72.93 ? 239 ASN B N 1 ATOM 5016 C CA . ASN B 2 207 ? 83.964 -2.782 -0.059 1.00 68.73 ? 239 ASN B CA 1 ATOM 5017 C C . ASN B 2 207 ? 82.662 -2.185 0.532 1.00 68.30 ? 239 ASN B C 1 ATOM 5018 O O . ASN B 2 207 ? 82.546 -0.977 0.684 1.00 66.82 ? 239 ASN B O 1 ATOM 5019 C CB . ASN B 2 207 ? 83.825 -3.160 -1.557 1.00 66.28 ? 239 ASN B CB 1 ATOM 5020 C CG . ASN B 2 207 ? 83.278 -2.027 -2.423 1.00 68.36 ? 239 ASN B CG 1 ATOM 5021 O OD1 . ASN B 2 207 ? 83.338 -0.864 -2.050 1.00 72.26 ? 239 ASN B OD1 1 ATOM 5022 N ND2 . ASN B 2 207 ? 82.745 -2.369 -3.598 1.00 69.15 ? 239 ASN B ND2 1 ATOM 5023 N N . SER B 2 208 ? 81.696 -3.022 0.894 1.00 72.32 ? 240 SER B N 1 ATOM 5024 C CA . SER B 2 208 ? 80.417 -2.526 1.433 1.00 74.57 ? 240 SER B CA 1 ATOM 5025 C C . SER B 2 208 ? 80.547 -1.977 2.862 1.00 75.16 ? 240 SER B C 1 ATOM 5026 O O . SER B 2 208 ? 79.786 -1.077 3.278 1.00 64.73 ? 240 SER B O 1 ATOM 5027 C CB . SER B 2 208 ? 79.366 -3.640 1.400 1.00 76.91 ? 240 SER B CB 1 ATOM 5028 O OG . SER B 2 208 ? 79.020 -3.985 0.069 1.00 75.98 ? 240 SER B OG 1 ATOM 5029 N N . GLN B 2 209 ? 81.517 -2.532 3.597 1.00 79.50 ? 241 GLN B N 1 ATOM 5030 C CA . GLN B 2 209 ? 81.750 -2.205 5.006 1.00 79.92 ? 241 GLN B CA 1 ATOM 5031 C C . GLN B 2 209 ? 82.021 -0.729 5.199 1.00 83.68 ? 241 GLN B C 1 ATOM 5032 O O . GLN B 2 209 ? 81.628 -0.163 6.215 1.00 88.11 ? 241 GLN B O 1 ATOM 5033 C CB . GLN B 2 209 ? 82.922 -3.016 5.564 1.00 76.29 ? 241 GLN B CB 1 ATOM 5034 C CG . GLN B 2 209 ? 83.119 -2.889 7.067 1.00 76.21 ? 241 GLN B CG 1 ATOM 5035 C CD . GLN B 2 209 ? 83.658 -4.174 7.698 1.00 77.95 ? 241 GLN B CD 1 ATOM 5036 O OE1 . GLN B 2 209 ? 82.951 -5.180 7.764 1.00 77.27 ? 241 GLN B OE1 1 ATOM 5037 N NE2 . GLN B 2 209 ? 84.910 -4.144 8.169 1.00 74.53 ? 241 GLN B NE2 1 ATOM 5038 N N . GLN B 2 210 ? 82.686 -0.114 4.221 1.00 86.14 ? 242 GLN B N 1 ATOM 5039 C CA . GLN B 2 210 ? 83.030 1.310 4.286 1.00 87.60 ? 242 GLN B CA 1 ATOM 5040 C C . GLN B 2 210 ? 82.037 2.227 3.585 1.00 85.41 ? 242 GLN B C 1 ATOM 5041 O O . GLN B 2 210 ? 81.849 3.360 4.018 1.00 91.65 ? 242 GLN B O 1 ATOM 5042 C CB . GLN B 2 210 ? 84.424 1.555 3.714 1.00 83.36 ? 242 GLN B CB 1 ATOM 5043 C CG . GLN B 2 210 ? 85.511 0.894 4.529 1.00 80.64 ? 242 GLN B CG 1 ATOM 5044 C CD . GLN B 2 210 ? 86.402 0.064 3.653 1.00 80.71 ? 242 GLN B CD 1 ATOM 5045 O OE1 . GLN B 2 210 ? 87.165 0.603 2.861 1.00 81.02 ? 242 GLN B OE1 1 ATOM 5046 N NE2 . GLN B 2 210 ? 86.291 -1.258 3.764 1.00 81.78 ? 242 GLN B NE2 1 ATOM 5047 N N . ASN B 2 211 ? 81.389 1.749 2.526 1.00 83.52 ? 243 ASN B N 1 ATOM 5048 C CA . ASN B 2 211 ? 80.474 2.602 1.743 1.00 82.57 ? 243 ASN B CA 1 ATOM 5049 C C . ASN B 2 211 ? 79.077 2.702 2.356 1.00 81.76 ? 243 ASN B C 1 ATOM 5050 O O . ASN B 2 211 ? 78.109 3.014 1.640 1.00 73.07 ? 243 ASN B O 1 ATOM 5051 C CB . ASN B 2 211 ? 80.365 2.106 0.290 1.00 81.18 ? 243 ASN B CB 1 ATOM 5052 C CG . ASN B 2 211 ? 81.722 1.868 -0.350 1.00 78.70 ? 243 ASN B CG 1 ATOM 5053 O OD1 . ASN B 2 211 ? 82.726 1.708 0.344 1.00 77.99 ? 243 ASN B OD1 1 ATOM 5054 N ND2 . ASN B 2 211 ? 81.760 1.846 -1.672 1.00 75.12 ? 243 ASN B ND2 1 ATOM 5055 N N . LYS B 2 212 ? 78.983 2.455 3.672 1.00 81.79 ? 244 LYS B N 1 ATOM 5056 C CA . LYS B 2 212 ? 77.713 2.443 4.379 1.00 83.02 ? 244 LYS B CA 1 ATOM 5057 C C . LYS B 2 212 ? 76.728 1.592 3.589 1.00 82.41 ? 244 LYS B C 1 ATOM 5058 O O . LYS B 2 212 ? 75.654 2.066 3.188 1.00 81.57 ? 244 LYS B O 1 ATOM 5059 C CB . LYS B 2 212 ? 77.178 3.879 4.582 1.00 85.73 ? 244 LYS B CB 1 ATOM 5060 C CG . LYS B 2 212 ? 76.995 4.305 6.038 1.00 88.47 ? 244 LYS B CG 1 ATOM 5061 C CD . LYS B 2 212 ? 75.731 5.146 6.213 1.00 89.08 ? 244 LYS B CD 1 ATOM 5062 C CE . LYS B 2 212 ? 75.425 5.453 7.674 1.00 89.77 ? 244 LYS B CE 1 ATOM 5063 N NZ . LYS B 2 212 ? 76.037 6.740 8.105 1.00 92.59 1 244 LYS B NZ 1 ATOM 5064 N N . GLU B 2 213 ? 77.115 0.344 3.329 1.00 79.40 ? 245 GLU B N 1 ATOM 5065 C CA . GLU B 2 213 ? 76.240 -0.565 2.594 1.00 76.92 ? 245 GLU B CA 1 ATOM 5066 C C . GLU B 2 213 ? 75.895 -1.822 3.386 1.00 70.01 ? 245 GLU B C 1 ATOM 5067 O O . GLU B 2 213 ? 76.681 -2.313 4.198 1.00 61.88 ? 245 GLU B O 1 ATOM 5068 C CB . GLU B 2 213 ? 76.808 -0.904 1.205 1.00 82.02 ? 245 GLU B CB 1 ATOM 5069 C CG . GLU B 2 213 ? 76.390 0.100 0.124 1.00 86.77 ? 245 GLU B CG 1 ATOM 5070 C CD . GLU B 2 213 ? 76.511 -0.427 -1.306 1.00 89.93 ? 245 GLU B CD 1 ATOM 5071 O OE1 . GLU B 2 213 ? 77.234 -1.425 -1.536 1.00 89.60 ? 245 GLU B OE1 1 ATOM 5072 O OE2 . GLU B 2 213 ? 75.883 0.174 -2.209 1.00 88.87 -1 245 GLU B OE2 1 ATOM 5073 N N . LYS B 2 214 ? 74.675 -2.299 3.150 1.00 69.34 ? 246 LYS B N 1 ATOM 5074 C CA . LYS B 2 214 ? 74.169 -3.536 3.733 1.00 65.88 ? 246 LYS B CA 1 ATOM 5075 C C . LYS B 2 214 ? 74.077 -4.609 2.632 1.00 60.73 ? 246 LYS B C 1 ATOM 5076 O O . LYS B 2 214 ? 73.594 -4.357 1.513 1.00 58.59 ? 246 LYS B O 1 ATOM 5077 C CB . LYS B 2 214 ? 72.806 -3.297 4.413 1.00 62.95 ? 246 LYS B CB 1 ATOM 5078 C CG . LYS B 2 214 ? 72.818 -2.196 5.474 1.00 61.42 ? 246 LYS B CG 1 ATOM 5079 C CD . LYS B 2 214 ? 73.707 -2.513 6.682 1.00 59.78 ? 246 LYS B CD 1 ATOM 5080 C CE . LYS B 2 214 ? 72.948 -3.281 7.753 1.00 59.99 ? 246 LYS B CE 1 ATOM 5081 N NZ . LYS B 2 214 ? 73.834 -3.970 8.732 1.00 58.15 1 246 LYS B NZ 1 ATOM 5082 N N . VAL B 2 215 ? 74.567 -5.797 2.966 1.00 52.94 ? 247 VAL B N 1 ATOM 5083 C CA . VAL B 2 215 ? 74.595 -6.911 2.048 1.00 49.98 ? 247 VAL B CA 1 ATOM 5084 C C . VAL B 2 215 ? 73.532 -7.938 2.454 1.00 48.08 ? 247 VAL B C 1 ATOM 5085 O O . VAL B 2 215 ? 73.333 -8.196 3.630 1.00 47.30 ? 247 VAL B O 1 ATOM 5086 C CB . VAL B 2 215 ? 76.004 -7.553 2.010 1.00 49.93 ? 247 VAL B CB 1 ATOM 5087 C CG1 . VAL B 2 215 ? 75.952 -9.002 1.542 1.00 51.05 ? 247 VAL B CG1 1 ATOM 5088 C CG2 . VAL B 2 215 ? 76.937 -6.751 1.113 1.00 48.73 ? 247 VAL B CG2 1 ATOM 5089 N N . TYR B 2 216 ? 72.843 -8.477 1.447 1.00 46.95 ? 248 TYR B N 1 ATOM 5090 C CA . TYR B 2 216 ? 71.969 -9.654 1.545 1.00 44.07 ? 248 TYR B CA 1 ATOM 5091 C C . TYR B 2 216 ? 72.608 -10.786 0.762 1.00 43.26 ? 248 TYR B C 1 ATOM 5092 O O . TYR B 2 216 ? 72.847 -10.618 -0.436 1.00 49.92 ? 248 TYR B O 1 ATOM 5093 C CB . TYR B 2 216 ? 70.612 -9.356 0.886 1.00 42.16 ? 248 TYR B CB 1 ATOM 5094 C CG . TYR B 2 216 ? 69.597 -8.652 1.749 1.00 41.20 ? 248 TYR B CG 1 ATOM 5095 C CD1 . TYR B 2 216 ? 69.856 -8.339 3.093 1.00 40.38 ? 248 TYR B CD1 1 ATOM 5096 C CD2 . TYR B 2 216 ? 68.349 -8.346 1.235 1.00 41.42 ? 248 TYR B CD2 1 ATOM 5097 C CE1 . TYR B 2 216 ? 68.901 -7.727 3.883 1.00 41.17 ? 248 TYR B CE1 1 ATOM 5098 C CE2 . TYR B 2 216 ? 67.387 -7.730 2.021 1.00 43.59 ? 248 TYR B CE2 1 ATOM 5099 C CZ . TYR B 2 216 ? 67.670 -7.421 3.346 1.00 42.97 ? 248 TYR B CZ 1 ATOM 5100 O OH . TYR B 2 216 ? 66.718 -6.802 4.124 1.00 45.17 ? 248 TYR B OH 1 ATOM 5101 N N . ILE B 2 217 ? 72.870 -11.932 1.380 1.00 39.23 ? 249 ILE B N 1 ATOM 5102 C CA . ILE B 2 217 ? 73.466 -13.018 0.618 1.00 38.47 ? 249 ILE B CA 1 ATOM 5103 C C . ILE B 2 217 ? 72.440 -13.956 0.007 1.00 39.15 ? 249 ILE B C 1 ATOM 5104 O O . ILE B 2 217 ? 71.591 -14.517 0.687 1.00 40.30 ? 249 ILE B O 1 ATOM 5105 C CB . ILE B 2 217 ? 74.408 -13.864 1.445 1.00 39.47 ? 249 ILE B CB 1 ATOM 5106 C CG1 . ILE B 2 217 ? 75.445 -12.996 2.138 1.00 40.72 ? 249 ILE B CG1 1 ATOM 5107 C CG2 . ILE B 2 217 ? 75.100 -14.861 0.542 1.00 40.71 ? 249 ILE B CG2 1 ATOM 5108 C CD1 . ILE B 2 217 ? 76.379 -12.283 1.196 1.00 40.55 ? 249 ILE B CD1 1 ATOM 5109 N N . ILE B 2 218 ? 72.570 -14.140 -1.293 1.00 39.67 ? 250 ILE B N 1 ATOM 5110 C CA . ILE B 2 218 ? 71.762 -15.055 -2.075 1.00 41.13 ? 250 ILE B CA 1 ATOM 5111 C C . ILE B 2 218 ? 72.719 -16.176 -2.474 1.00 42.08 ? 250 ILE B C 1 ATOM 5112 O O . ILE B 2 218 ? 73.823 -15.922 -2.995 1.00 40.69 ? 250 ILE B O 1 ATOM 5113 C CB . ILE B 2 218 ? 71.184 -14.317 -3.329 1.00 42.35 ? 250 ILE B CB 1 ATOM 5114 C CG1 . ILE B 2 218 ? 69.825 -13.755 -3.006 1.00 44.82 ? 250 ILE B CG1 1 ATOM 5115 C CG2 . ILE B 2 218 ? 71.005 -15.215 -4.548 1.00 40.64 ? 250 ILE B CG2 1 ATOM 5116 C CD1 . ILE B 2 218 ? 69.780 -12.958 -1.727 1.00 47.20 ? 250 ILE B CD1 1 ATOM 5117 N N . ALA B 2 219 ? 72.328 -17.415 -2.208 1.00 40.31 ? 251 ALA B N 1 ATOM 5118 C CA . ALA B 2 219 ? 72.999 -18.536 -2.843 1.00 39.28 ? 251 ALA B CA 1 ATOM 5119 C C . ALA B 2 219 ? 72.049 -19.712 -2.960 1.00 40.72 ? 251 ALA B C 1 ATOM 5120 O O . ALA B 2 219 ? 70.896 -19.635 -2.500 1.00 39.73 ? 251 ALA B O 1 ATOM 5121 C CB . ALA B 2 219 ? 74.247 -18.912 -2.069 1.00 38.78 ? 251 ALA B CB 1 ATOM 5122 N N . HIS B 2 220 ? 72.540 -20.785 -3.595 1.00 43.33 ? 252 HIS B N 1 ATOM 5123 C CA . HIS B 2 220 ? 71.792 -22.068 -3.736 1.00 43.29 ? 252 HIS B CA 1 ATOM 5124 C C . HIS B 2 220 ? 72.062 -23.122 -2.638 1.00 39.83 ? 252 HIS B C 1 ATOM 5125 O O . HIS B 2 220 ? 71.230 -23.326 -1.741 1.00 37.25 ? 252 HIS B O 1 ATOM 5126 C CB . HIS B 2 220 ? 72.060 -22.707 -5.114 1.00 43.46 ? 252 HIS B CB 1 ATOM 5127 C CG . HIS B 2 220 ? 71.204 -23.898 -5.387 1.00 41.02 ? 252 HIS B CG 1 ATOM 5128 N ND1 . HIS B 2 220 ? 69.836 -23.806 -5.521 1.00 41.28 ? 252 HIS B ND1 1 ATOM 5129 C CD2 . HIS B 2 220 ? 71.510 -25.205 -5.527 1.00 41.94 ? 252 HIS B CD2 1 ATOM 5130 C CE1 . HIS B 2 220 ? 69.336 -25.005 -5.746 1.00 41.60 ? 252 HIS B CE1 1 ATOM 5131 N NE2 . HIS B 2 220 ? 70.331 -25.872 -5.755 1.00 42.71 ? 252 HIS B NE2 1 ATOM 5132 N N . VAL B 2 221 ? 73.210 -23.791 -2.732 1.00 36.61 ? 253 VAL B N 1 ATOM 5133 C CA . VAL B 2 221 ? 73.590 -24.772 -1.739 1.00 36.06 ? 253 VAL B CA 1 ATOM 5134 C C . VAL B 2 221 ? 73.898 -23.950 -0.488 1.00 35.91 ? 253 VAL B C 1 ATOM 5135 O O . VAL B 2 221 ? 74.791 -23.108 -0.519 1.00 41.78 ? 253 VAL B O 1 ATOM 5136 C CB . VAL B 2 221 ? 74.798 -25.614 -2.226 1.00 34.66 ? 253 VAL B CB 1 ATOM 5137 C CG1 . VAL B 2 221 ? 75.188 -26.702 -1.222 1.00 34.16 ? 253 VAL B CG1 1 ATOM 5138 C CG2 . VAL B 2 221 ? 74.449 -26.266 -3.549 1.00 33.87 ? 253 VAL B CG2 1 ATOM 5139 N N . PRO B 2 222 ? 73.151 -24.156 0.605 1.00 34.66 ? 254 PRO B N 1 ATOM 5140 C CA . PRO B 2 222 ? 73.465 -23.361 1.765 1.00 35.54 ? 254 PRO B CA 1 ATOM 5141 C C . PRO B 2 222 ? 74.795 -23.795 2.452 1.00 36.36 ? 254 PRO B C 1 ATOM 5142 O O . PRO B 2 222 ? 75.401 -24.821 2.112 1.00 34.58 ? 254 PRO B O 1 ATOM 5143 C CB . PRO B 2 222 ? 72.269 -23.644 2.686 1.00 37.14 ? 254 PRO B CB 1 ATOM 5144 C CG . PRO B 2 222 ? 71.932 -25.086 2.425 1.00 36.79 ? 254 PRO B CG 1 ATOM 5145 C CD . PRO B 2 222 ? 72.242 -25.268 0.947 1.00 36.94 ? 254 PRO B CD 1 ATOM 5146 N N . VAL B 2 223 ? 75.230 -22.993 3.411 1.00 36.17 ? 255 VAL B N 1 ATOM 5147 C CA . VAL B 2 223 ? 76.204 -23.426 4.406 1.00 36.41 ? 255 VAL B CA 1 ATOM 5148 C C . VAL B 2 223 ? 75.596 -24.310 5.527 1.00 33.96 ? 255 VAL B C 1 ATOM 5149 O O . VAL B 2 223 ? 74.373 -24.502 5.648 1.00 30.25 ? 255 VAL B O 1 ATOM 5150 C CB . VAL B 2 223 ? 76.902 -22.203 5.064 1.00 39.24 ? 255 VAL B CB 1 ATOM 5151 C CG1 . VAL B 2 223 ? 77.585 -21.346 3.999 1.00 38.86 ? 255 VAL B CG1 1 ATOM 5152 C CG2 . VAL B 2 223 ? 75.912 -21.382 5.909 1.00 39.13 ? 255 VAL B CG2 1 ATOM 5153 N N . GLY B 2 224 ? 76.489 -24.848 6.343 1.00 34.05 ? 256 GLY B N 1 ATOM 5154 C CA . GLY B 2 224 ? 76.108 -25.548 7.552 1.00 33.73 ? 256 GLY B CA 1 ATOM 5155 C C . GLY B 2 224 ? 75.655 -26.960 7.284 1.00 32.86 ? 256 GLY B C 1 ATOM 5156 O O . GLY B 2 224 ? 75.849 -27.503 6.199 1.00 31.30 ? 256 GLY B O 1 ATOM 5157 N N . TYR B 2 225 ? 75.016 -27.539 8.287 1.00 33.05 ? 257 TYR B N 1 ATOM 5158 C CA . TYR B 2 225 ? 74.694 -28.954 8.265 1.00 34.89 ? 257 TYR B CA 1 ATOM 5159 C C . TYR B 2 225 ? 73.305 -29.204 7.684 1.00 35.50 ? 257 TYR B C 1 ATOM 5160 O O . TYR B 2 225 ? 72.383 -28.417 7.870 1.00 36.86 ? 257 TYR B O 1 ATOM 5161 C CB . TYR B 2 225 ? 74.931 -29.559 9.663 1.00 33.86 ? 257 TYR B CB 1 ATOM 5162 C CG . TYR B 2 225 ? 76.432 -29.760 9.925 1.00 33.40 ? 257 TYR B CG 1 ATOM 5163 C CD1 . TYR B 2 225 ? 77.271 -28.685 10.225 1.00 32.85 ? 257 TYR B CD1 1 ATOM 5164 C CD2 . TYR B 2 225 ? 77.015 -31.005 9.798 1.00 34.11 ? 257 TYR B CD2 1 ATOM 5165 C CE1 . TYR B 2 225 ? 78.627 -28.864 10.421 1.00 32.58 ? 257 TYR B CE1 1 ATOM 5166 C CE2 . TYR B 2 225 ? 78.363 -31.186 9.988 1.00 34.36 ? 257 TYR B CE2 1 ATOM 5167 C CZ . TYR B 2 225 ? 79.154 -30.125 10.304 1.00 33.99 ? 257 TYR B CZ 1 ATOM 5168 O OH . TYR B 2 225 ? 80.476 -30.393 10.479 1.00 36.65 ? 257 TYR B OH 1 ATOM 5169 N N . LEU B 2 226 ? 73.175 -30.264 6.908 1.00 36.07 ? 258 LEU B N 1 ATOM 5170 C CA . LEU B 2 226 ? 71.869 -30.621 6.400 1.00 39.32 ? 258 LEU B CA 1 ATOM 5171 C C . LEU B 2 226 ? 71.079 -31.039 7.602 1.00 39.60 ? 258 LEU B C 1 ATOM 5172 O O . LEU B 2 226 ? 71.598 -31.790 8.440 1.00 42.37 ? 258 LEU B O 1 ATOM 5173 C CB . LEU B 2 226 ? 71.943 -31.789 5.426 1.00 41.16 ? 258 LEU B CB 1 ATOM 5174 C CG . LEU B 2 226 ? 72.612 -31.480 4.096 1.00 39.56 ? 258 LEU B CG 1 ATOM 5175 C CD1 . LEU B 2 226 ? 72.886 -32.799 3.384 1.00 37.39 ? 258 LEU B CD1 1 ATOM 5176 C CD2 . LEU B 2 226 ? 71.713 -30.522 3.304 1.00 39.98 ? 258 LEU B CD2 1 ATOM 5177 N N . PRO B 2 227 ? 69.836 -30.546 7.727 1.00 37.99 ? 259 PRO B N 1 ATOM 5178 C CA . PRO B 2 227 ? 69.230 -30.842 9.017 1.00 36.41 ? 259 PRO B CA 1 ATOM 5179 C C . PRO B 2 227 ? 68.724 -32.292 9.135 1.00 34.28 ? 259 PRO B C 1 ATOM 5180 O O . PRO B 2 227 ? 68.652 -32.825 10.242 1.00 33.47 ? 259 PRO B O 1 ATOM 5181 C CB . PRO B 2 227 ? 68.111 -29.780 9.146 1.00 35.95 ? 259 PRO B CB 1 ATOM 5182 C CG . PRO B 2 227 ? 68.087 -29.012 7.866 1.00 36.34 ? 259 PRO B CG 1 ATOM 5183 C CD . PRO B 2 227 ? 68.967 -29.715 6.875 1.00 37.24 ? 259 PRO B CD 1 ATOM 5184 N N . SER B 2 228 ? 68.433 -32.951 8.020 1.00 32.58 ? 260 SER B N 1 ATOM 5185 C CA . SER B 2 228 ? 67.736 -34.219 8.125 1.00 33.11 ? 260 SER B CA 1 ATOM 5186 C C . SER B 2 228 ? 68.672 -35.419 8.049 1.00 35.30 ? 260 SER B C 1 ATOM 5187 O O . SER B 2 228 ? 68.253 -36.535 7.688 1.00 34.35 ? 260 SER B O 1 ATOM 5188 C CB . SER B 2 228 ? 66.565 -34.273 7.141 1.00 31.32 ? 260 SER B CB 1 ATOM 5189 O OG . SER B 2 228 ? 65.421 -33.752 7.811 1.00 28.76 ? 260 SER B OG 1 ATOM 5190 N N . SER B 2 229 ? 69.921 -35.182 8.471 1.00 38.68 ? 261 SER B N 1 ATOM 5191 C CA . SER B 2 229 ? 70.993 -36.195 8.483 1.00 41.80 ? 261 SER B CA 1 ATOM 5192 C C . SER B 2 229 ? 72.211 -35.785 9.372 1.00 43.89 ? 261 SER B C 1 ATOM 5193 O O . SER B 2 229 ? 72.447 -34.597 9.590 1.00 44.33 ? 261 SER B O 1 ATOM 5194 C CB . SER B 2 229 ? 71.433 -36.545 7.030 1.00 41.99 ? 261 SER B CB 1 ATOM 5195 O OG . SER B 2 229 ? 71.617 -35.411 6.183 1.00 39.15 ? 261 SER B OG 1 ATOM 5196 N N . GLN B 2 230 ? 72.984 -36.767 9.857 1.00 47.14 ? 262 GLN B N 1 ATOM 5197 C CA . GLN B 2 230 ? 74.059 -36.512 10.846 1.00 48.39 ? 262 GLN B CA 1 ATOM 5198 C C . GLN B 2 230 ? 75.490 -36.205 10.313 1.00 48.72 ? 262 GLN B C 1 ATOM 5199 O O . GLN B 2 230 ? 76.071 -36.964 9.519 1.00 52.39 ? 262 GLN B O 1 ATOM 5200 C CB . GLN B 2 230 ? 74.102 -37.650 11.876 1.00 48.36 ? 262 GLN B CB 1 ATOM 5201 C CG . GLN B 2 230 ? 75.147 -38.739 11.700 1.00 47.72 ? 262 GLN B CG 1 ATOM 5202 C CD . GLN B 2 230 ? 75.239 -39.599 12.945 1.00 46.72 ? 262 GLN B CD 1 ATOM 5203 O OE1 . GLN B 2 230 ? 75.568 -39.111 14.024 1.00 40.76 ? 262 GLN B OE1 1 ATOM 5204 N NE2 . GLN B 2 230 ? 74.927 -40.885 12.805 1.00 48.72 ? 262 GLN B NE2 1 ATOM 5205 N N . ASN B 2 231 ? 76.072 -35.113 10.806 1.00 45.88 ? 263 ASN B N 1 ATOM 5206 C CA . ASN B 2 231 ? 77.429 -34.674 10.499 1.00 44.34 ? 263 ASN B CA 1 ATOM 5207 C C . ASN B 2 231 ? 77.703 -34.340 9.063 1.00 42.47 ? 263 ASN B C 1 ATOM 5208 O O . ASN B 2 231 ? 78.833 -34.238 8.671 1.00 45.49 ? 263 ASN B O 1 ATOM 5209 C CB . ASN B 2 231 ? 78.434 -35.711 11.000 1.00 46.96 ? 263 ASN B CB 1 ATOM 5210 C CG . ASN B 2 231 ? 79.871 -35.231 10.949 1.00 52.67 ? 263 ASN B CG 1 ATOM 5211 O OD1 . ASN B 2 231 ? 80.120 -34.060 10.866 1.00 55.02 ? 263 ASN B OD1 1 ATOM 5212 N ND2 . ASN B 2 231 ? 80.817 -36.150 10.968 1.00 59.37 ? 263 ASN B ND2 1 ATOM 5213 N N . ILE B 2 232 ? 76.681 -34.150 8.253 1.00 38.59 ? 264 ILE B N 1 ATOM 5214 C CA . ILE B 2 232 ? 76.925 -33.853 6.830 1.00 36.46 ? 264 ILE B CA 1 ATOM 5215 C C . ILE B 2 232 ? 76.650 -32.394 6.491 1.00 35.32 ? 264 ILE B C 1 ATOM 5216 O O . ILE B 2 232 ? 75.485 -31.966 6.460 1.00 36.39 ? 264 ILE B O 1 ATOM 5217 C CB . ILE B 2 232 ? 76.066 -34.722 5.896 1.00 35.79 ? 264 ILE B CB 1 ATOM 5218 C CG1 . ILE B 2 232 ? 76.280 -36.209 6.204 1.00 36.85 ? 264 ILE B CG1 1 ATOM 5219 C CG2 . ILE B 2 232 ? 76.376 -34.395 4.436 1.00 34.05 ? 264 ILE B CG2 1 ATOM 5220 C CD1 . ILE B 2 232 ? 75.080 -37.079 5.899 1.00 36.94 ? 264 ILE B CD1 1 ATOM 5221 N N . THR B 2 233 ? 77.710 -31.633 6.215 1.00 32.87 ? 265 THR B N 1 ATOM 5222 C CA . THR B 2 233 ? 77.526 -30.290 5.705 1.00 31.70 ? 265 THR B CA 1 ATOM 5223 C C . THR B 2 233 ? 76.986 -30.480 4.313 1.00 30.29 ? 265 THR B C 1 ATOM 5224 O O . THR B 2 233 ? 77.009 -31.583 3.799 1.00 29.47 ? 265 THR B O 1 ATOM 5225 C CB . THR B 2 233 ? 78.821 -29.512 5.679 1.00 32.08 ? 265 THR B CB 1 ATOM 5226 O OG1 . THR B 2 233 ? 79.753 -30.233 4.893 1.00 33.70 ? 265 THR B OG1 1 ATOM 5227 C CG2 . THR B 2 233 ? 79.374 -29.370 7.071 1.00 31.84 ? 265 THR B CG2 1 ATOM 5228 N N . ALA B 2 234 ? 76.457 -29.430 3.720 1.00 31.19 ? 266 ALA B N 1 ATOM 5229 C CA . ALA B 2 234 ? 75.795 -29.556 2.418 1.00 34.34 ? 266 ALA B CA 1 ATOM 5230 C C . ALA B 2 234 ? 76.824 -29.398 1.299 1.00 35.77 ? 266 ALA B C 1 ATOM 5231 O O . ALA B 2 234 ? 76.884 -30.178 0.338 1.00 34.21 ? 266 ALA B O 1 ATOM 5232 C CB . ALA B 2 234 ? 74.700 -28.503 2.290 1.00 35.14 ? 266 ALA B CB 1 ATOM 5233 N N . MET B 2 235 ? 77.634 -28.361 1.464 1.00 38.21 ? 267 MET B N 1 ATOM 5234 C CA . MET B 2 235 ? 78.823 -28.118 0.671 1.00 38.67 ? 267 MET B CA 1 ATOM 5235 C C . MET B 2 235 ? 79.845 -29.122 1.106 1.00 41.08 ? 267 MET B C 1 ATOM 5236 O O . MET B 2 235 ? 79.538 -29.994 1.897 1.00 43.81 ? 267 MET B O 1 ATOM 5237 C CB . MET B 2 235 ? 79.366 -26.715 0.990 1.00 37.96 ? 267 MET B CB 1 ATOM 5238 C CG . MET B 2 235 ? 78.519 -25.566 0.444 1.00 37.43 ? 267 MET B CG 1 ATOM 5239 S SD . MET B 2 235 ? 78.812 -23.970 1.228 1.00 33.15 ? 267 MET B SD 1 ATOM 5240 C CE . MET B 2 235 ? 80.563 -24.134 1.491 1.00 33.60 ? 267 MET B CE 1 ATOM 5241 N N . ARG B 2 236 ? 81.065 -28.993 0.597 1.00 46.24 ? 268 ARG B N 1 ATOM 5242 C CA . ARG B 2 236 ? 82.225 -29.673 1.196 1.00 48.86 ? 268 ARG B CA 1 ATOM 5243 C C . ARG B 2 236 ? 82.661 -28.998 2.523 1.00 47.45 ? 268 ARG B C 1 ATOM 5244 O O . ARG B 2 236 ? 82.871 -27.777 2.610 1.00 40.53 ? 268 ARG B O 1 ATOM 5245 C CB . ARG B 2 236 ? 83.405 -29.789 0.204 1.00 48.56 ? 268 ARG B CB 1 ATOM 5246 C CG . ARG B 2 236 ? 83.290 -30.944 -0.786 1.00 46.65 ? 268 ARG B CG 1 ATOM 5247 C CD . ARG B 2 236 ? 84.457 -30.969 -1.769 1.00 46.91 ? 268 ARG B CD 1 ATOM 5248 N NE . ARG B 2 236 ? 83.998 -31.304 -3.126 1.00 48.80 ? 268 ARG B NE 1 ATOM 5249 C CZ . ARG B 2 236 ? 84.244 -30.605 -4.239 1.00 48.11 ? 268 ARG B CZ 1 ATOM 5250 N NH1 . ARG B 2 236 ? 84.995 -29.505 -4.223 1.00 47.40 1 268 ARG B NH1 1 ATOM 5251 N NH2 . ARG B 2 236 ? 83.739 -31.030 -5.392 1.00 47.82 ? 268 ARG B NH2 1 ATOM 5252 N N . GLU B 2 237 ? 82.764 -29.838 3.549 1.00 50.20 ? 269 GLU B N 1 ATOM 5253 C CA . GLU B 2 237 ? 83.212 -29.444 4.862 1.00 53.84 ? 269 GLU B CA 1 ATOM 5254 C C . GLU B 2 237 ? 84.210 -28.340 4.757 1.00 51.61 ? 269 GLU B C 1 ATOM 5255 O O . GLU B 2 237 ? 84.104 -27.341 5.471 1.00 46.29 ? 269 GLU B O 1 ATOM 5256 C CB . GLU B 2 237 ? 83.920 -30.636 5.524 1.00 59.88 ? 269 GLU B CB 1 ATOM 5257 C CG . GLU B 2 237 ? 85.073 -30.318 6.471 1.00 67.45 ? 269 GLU B CG 1 ATOM 5258 C CD . GLU B 2 237 ? 84.646 -30.219 7.921 1.00 72.79 ? 269 GLU B CD 1 ATOM 5259 O OE1 . GLU B 2 237 ? 84.219 -29.116 8.326 1.00 78.27 ? 269 GLU B OE1 1 ATOM 5260 O OE2 . GLU B 2 237 ? 84.760 -31.234 8.652 1.00 72.10 -1 269 GLU B OE2 1 ATOM 5261 N N . TYR B 2 238 ? 85.155 -28.532 3.829 1.00 53.52 ? 270 TYR B N 1 ATOM 5262 C CA . TYR B 2 238 ? 86.276 -27.604 3.644 1.00 58.48 ? 270 TYR B CA 1 ATOM 5263 C C . TYR B 2 238 ? 85.824 -26.186 3.287 1.00 55.72 ? 270 TYR B C 1 ATOM 5264 O O . TYR B 2 238 ? 86.338 -25.204 3.844 1.00 53.55 ? 270 TYR B O 1 ATOM 5265 C CB . TYR B 2 238 ? 87.316 -28.123 2.606 1.00 61.85 ? 270 TYR B CB 1 ATOM 5266 C CG . TYR B 2 238 ? 88.421 -27.100 2.331 1.00 66.93 ? 270 TYR B CG 1 ATOM 5267 C CD1 . TYR B 2 238 ? 89.526 -26.971 3.187 1.00 69.05 ? 270 TYR B CD1 1 ATOM 5268 C CD2 . TYR B 2 238 ? 88.327 -26.220 1.250 1.00 68.78 ? 270 TYR B CD2 1 ATOM 5269 C CE1 . TYR B 2 238 ? 90.509 -26.015 2.953 1.00 70.94 ? 270 TYR B CE1 1 ATOM 5270 C CE2 . TYR B 2 238 ? 89.303 -25.260 1.011 1.00 71.21 ? 270 TYR B CE2 1 ATOM 5271 C CZ . TYR B 2 238 ? 90.392 -25.155 1.860 1.00 71.50 ? 270 TYR B CZ 1 ATOM 5272 O OH . TYR B 2 238 ? 91.350 -24.188 1.613 1.00 66.27 ? 270 TYR B OH 1 ATOM 5273 N N . TYR B 2 239 ? 84.882 -26.063 2.359 1.00 53.55 ? 271 TYR B N 1 ATOM 5274 C CA . TYR B 2 239 ? 84.444 -24.738 1.982 1.00 52.59 ? 271 TYR B CA 1 ATOM 5275 C C . TYR B 2 239 ? 83.454 -24.220 2.992 1.00 51.72 ? 271 TYR B C 1 ATOM 5276 O O . TYR B 2 239 ? 83.437 -23.022 3.253 1.00 49.69 ? 271 TYR B O 1 ATOM 5277 C CB . TYR B 2 239 ? 83.794 -24.712 0.623 1.00 54.43 ? 271 TYR B CB 1 ATOM 5278 C CG . TYR B 2 239 ? 84.645 -25.188 -0.512 1.00 56.54 ? 271 TYR B CG 1 ATOM 5279 C CD1 . TYR B 2 239 ? 85.731 -24.470 -0.952 1.00 56.09 ? 271 TYR B CD1 1 ATOM 5280 C CD2 . TYR B 2 239 ? 84.315 -26.349 -1.176 1.00 59.90 ? 271 TYR B CD2 1 ATOM 5281 C CE1 . TYR B 2 239 ? 86.484 -24.921 -2.014 1.00 60.43 ? 271 TYR B CE1 1 ATOM 5282 C CE2 . TYR B 2 239 ? 85.047 -26.805 -2.235 1.00 61.92 ? 271 TYR B CE2 1 ATOM 5283 C CZ . TYR B 2 239 ? 86.130 -26.099 -2.659 1.00 62.48 ? 271 TYR B CZ 1 ATOM 5284 O OH . TYR B 2 239 ? 86.826 -26.607 -3.736 1.00 65.73 ? 271 TYR B OH 1 ATOM 5285 N N . ASN B 2 240 ? 82.614 -25.093 3.555 1.00 52.01 ? 272 ASN B N 1 ATOM 5286 C CA . ASN B 2 240 ? 81.655 -24.618 4.549 1.00 50.32 ? 272 ASN B CA 1 ATOM 5287 C C . ASN B 2 240 ? 82.366 -23.845 5.636 1.00 50.53 ? 272 ASN B C 1 ATOM 5288 O O . ASN B 2 240 ? 81.930 -22.748 5.988 1.00 46.54 ? 272 ASN B O 1 ATOM 5289 C CB . ASN B 2 240 ? 80.859 -25.730 5.205 1.00 50.20 ? 272 ASN B CB 1 ATOM 5290 C CG . ASN B 2 240 ? 80.066 -25.214 6.388 1.00 45.98 ? 272 ASN B CG 1 ATOM 5291 O OD1 . ASN B 2 240 ? 79.153 -24.418 6.211 1.00 43.07 ? 272 ASN B OD1 1 ATOM 5292 N ND2 . ASN B 2 240 ? 80.454 -25.601 7.597 1.00 43.04 ? 272 ASN B ND2 1 ATOM 5293 N N . GLU B 2 241 ? 83.460 -24.430 6.142 1.00 52.62 ? 273 GLU B N 1 ATOM 5294 C CA . GLU B 2 241 ? 84.313 -23.813 7.186 1.00 54.80 ? 273 GLU B CA 1 ATOM 5295 C C . GLU B 2 241 ? 84.864 -22.437 6.788 1.00 55.83 ? 273 GLU B C 1 ATOM 5296 O O . GLU B 2 241 ? 84.907 -21.506 7.607 1.00 54.32 ? 273 GLU B O 1 ATOM 5297 C CB . GLU B 2 241 ? 85.499 -24.727 7.514 1.00 52.95 ? 273 GLU B CB 1 ATOM 5298 C CG . GLU B 2 241 ? 85.139 -26.031 8.216 1.00 54.49 ? 273 GLU B CG 1 ATOM 5299 C CD . GLU B 2 241 ? 84.657 -25.836 9.647 1.00 56.91 ? 273 GLU B CD 1 ATOM 5300 O OE1 . GLU B 2 241 ? 84.974 -24.803 10.278 1.00 58.07 ? 273 GLU B OE1 1 ATOM 5301 O OE2 . GLU B 2 241 ? 83.954 -26.734 10.150 1.00 60.61 -1 273 GLU B OE2 1 ATOM 5302 N N . LYS B 2 242 ? 85.275 -22.351 5.522 1.00 54.89 ? 274 LYS B N 1 ATOM 5303 C CA . LYS B 2 242 ? 85.927 -21.179 4.936 1.00 54.60 ? 274 LYS B CA 1 ATOM 5304 C C . LYS B 2 242 ? 84.952 -20.024 4.748 1.00 50.65 ? 274 LYS B C 1 ATOM 5305 O O . LYS B 2 242 ? 85.325 -18.874 4.886 1.00 49.25 ? 274 LYS B O 1 ATOM 5306 C CB . LYS B 2 242 ? 86.521 -21.589 3.582 1.00 59.55 ? 274 LYS B CB 1 ATOM 5307 C CG . LYS B 2 242 ? 87.805 -20.899 3.154 1.00 63.41 ? 274 LYS B CG 1 ATOM 5308 C CD . LYS B 2 242 ? 88.672 -21.872 2.352 1.00 66.31 ? 274 LYS B CD 1 ATOM 5309 C CE . LYS B 2 242 ? 89.662 -21.160 1.443 1.00 68.84 ? 274 LYS B CE 1 ATOM 5310 N NZ . LYS B 2 242 ? 90.730 -20.479 2.224 1.00 71.59 1 274 LYS B NZ 1 ATOM 5311 N N . LEU B 2 243 ? 83.707 -20.348 4.414 1.00 49.84 ? 275 LEU B N 1 ATOM 5312 C CA . LEU B 2 243 ? 82.641 -19.361 4.249 1.00 48.40 ? 275 LEU B CA 1 ATOM 5313 C C . LEU B 2 243 ? 82.065 -18.913 5.580 1.00 52.36 ? 275 LEU B C 1 ATOM 5314 O O . LEU B 2 243 ? 81.610 -17.773 5.707 1.00 52.85 ? 275 LEU B O 1 ATOM 5315 C CB . LEU B 2 243 ? 81.490 -19.949 3.444 1.00 47.51 ? 275 LEU B CB 1 ATOM 5316 C CG . LEU B 2 243 ? 81.624 -20.055 1.938 1.00 47.94 ? 275 LEU B CG 1 ATOM 5317 C CD1 . LEU B 2 243 ? 80.380 -20.718 1.366 1.00 48.88 ? 275 LEU B CD1 1 ATOM 5318 C CD2 . LEU B 2 243 ? 81.835 -18.685 1.308 1.00 49.16 ? 275 LEU B CD2 1 ATOM 5319 N N . ILE B 2 244 ? 82.029 -19.825 6.555 1.00 54.45 ? 276 ILE B N 1 ATOM 5320 C CA . ILE B 2 244 ? 81.563 -19.494 7.907 1.00 53.96 ? 276 ILE B CA 1 ATOM 5321 C C . ILE B 2 244 ? 82.424 -18.374 8.469 1.00 52.21 ? 276 ILE B C 1 ATOM 5322 O O . ILE B 2 244 ? 81.917 -17.321 8.856 1.00 45.95 ? 276 ILE B O 1 ATOM 5323 C CB . ILE B 2 244 ? 81.605 -20.734 8.831 1.00 54.74 ? 276 ILE B CB 1 ATOM 5324 C CG1 . ILE B 2 244 ? 80.486 -21.713 8.459 1.00 59.60 ? 276 ILE B CG1 1 ATOM 5325 C CG2 . ILE B 2 244 ? 81.476 -20.340 10.291 1.00 54.92 ? 276 ILE B CG2 1 ATOM 5326 C CD1 . ILE B 2 244 ? 79.150 -21.064 8.122 1.00 60.93 ? 276 ILE B CD1 1 ATOM 5327 N N . ASP B 2 245 ? 83.731 -18.609 8.462 1.00 53.80 ? 277 ASP B N 1 ATOM 5328 C CA . ASP B 2 245 ? 84.688 -17.632 8.921 1.00 56.39 ? 277 ASP B CA 1 ATOM 5329 C C . ASP B 2 245 ? 84.466 -16.307 8.209 1.00 54.67 ? 277 ASP B C 1 ATOM 5330 O O . ASP B 2 245 ? 84.380 -15.268 8.866 1.00 55.80 ? 277 ASP B O 1 ATOM 5331 C CB . ASP B 2 245 ? 86.108 -18.156 8.729 1.00 63.04 ? 277 ASP B CB 1 ATOM 5332 C CG . ASP B 2 245 ? 86.439 -19.316 9.686 1.00 72.28 ? 277 ASP B CG 1 ATOM 5333 O OD1 . ASP B 2 245 ? 86.235 -19.150 10.909 1.00 77.87 ? 277 ASP B OD1 1 ATOM 5334 O OD2 . ASP B 2 245 ? 86.899 -20.393 9.225 1.00 77.95 -1 277 ASP B OD2 1 ATOM 5335 N N . ILE B 2 246 ? 84.316 -16.343 6.887 1.00 51.67 ? 278 ILE B N 1 ATOM 5336 C CA . ILE B 2 246 ? 84.041 -15.120 6.117 1.00 52.57 ? 278 ILE B CA 1 ATOM 5337 C C . ILE B 2 246 ? 82.751 -14.469 6.586 1.00 52.90 ? 278 ILE B C 1 ATOM 5338 O O . ILE B 2 246 ? 82.674 -13.239 6.658 1.00 53.36 ? 278 ILE B O 1 ATOM 5339 C CB . ILE B 2 246 ? 83.947 -15.353 4.572 1.00 53.68 ? 278 ILE B CB 1 ATOM 5340 C CG1 . ILE B 2 246 ? 85.319 -15.718 3.987 1.00 53.86 ? 278 ILE B CG1 1 ATOM 5341 C CG2 . ILE B 2 246 ? 83.411 -14.105 3.839 1.00 52.44 ? 278 ILE B CG2 1 ATOM 5342 C CD1 . ILE B 2 246 ? 85.261 -16.424 2.643 1.00 53.40 ? 278 ILE B CD1 1 ATOM 5343 N N . PHE B 2 247 ? 81.732 -15.281 6.869 1.00 54.12 ? 279 PHE B N 1 ATOM 5344 C CA . PHE B 2 247 ? 80.435 -14.739 7.289 1.00 55.78 ? 279 PHE B CA 1 ATOM 5345 C C . PHE B 2 247 ? 80.585 -14.174 8.694 1.00 51.74 ? 279 PHE B C 1 ATOM 5346 O O . PHE B 2 247 ? 80.033 -13.124 9.016 1.00 45.45 ? 279 PHE B O 1 ATOM 5347 C CB . PHE B 2 247 ? 79.308 -15.800 7.229 1.00 60.38 ? 279 PHE B CB 1 ATOM 5348 C CG . PHE B 2 247 ? 78.888 -16.211 5.817 1.00 63.85 ? 279 PHE B CG 1 ATOM 5349 C CD1 . PHE B 2 247 ? 78.770 -15.268 4.776 1.00 65.30 ? 279 PHE B CD1 1 ATOM 5350 C CD2 . PHE B 2 247 ? 78.558 -17.541 5.536 1.00 62.93 ? 279 PHE B CD2 1 ATOM 5351 C CE1 . PHE B 2 247 ? 78.373 -15.652 3.493 1.00 64.36 ? 279 PHE B CE1 1 ATOM 5352 C CE2 . PHE B 2 247 ? 78.160 -17.921 4.254 1.00 64.01 ? 279 PHE B CE2 1 ATOM 5353 C CZ . PHE B 2 247 ? 78.068 -16.982 3.233 1.00 64.72 ? 279 PHE B CZ 1 ATOM 5354 N N . GLN B 2 248 ? 81.368 -14.869 9.513 1.00 51.92 ? 280 GLN B N 1 ATOM 5355 C CA . GLN B 2 248 ? 81.668 -14.414 10.857 1.00 51.77 ? 280 GLN B CA 1 ATOM 5356 C C . GLN B 2 248 ? 82.340 -13.052 10.869 1.00 55.97 ? 280 GLN B C 1 ATOM 5357 O O . GLN B 2 248 ? 81.815 -12.112 11.484 1.00 56.79 ? 280 GLN B O 1 ATOM 5358 C CB . GLN B 2 248 ? 82.532 -15.432 11.580 1.00 49.44 ? 280 GLN B CB 1 ATOM 5359 C CG . GLN B 2 248 ? 81.692 -16.458 12.303 1.00 48.28 ? 280 GLN B CG 1 ATOM 5360 C CD . GLN B 2 248 ? 82.467 -17.704 12.658 1.00 48.79 ? 280 GLN B CD 1 ATOM 5361 O OE1 . GLN B 2 248 ? 83.527 -17.995 12.095 1.00 48.87 ? 280 GLN B OE1 1 ATOM 5362 N NE2 . GLN B 2 248 ? 81.930 -18.463 13.590 1.00 48.85 ? 280 GLN B NE2 1 ATOM 5363 N N . LYS B 2 249 ? 83.486 -12.940 10.195 1.00 57.92 ? 281 LYS B N 1 ATOM 5364 C CA . LYS B 2 249 ? 84.203 -11.656 10.123 1.00 59.53 ? 281 LYS B CA 1 ATOM 5365 C C . LYS B 2 249 ? 83.267 -10.480 9.721 1.00 59.75 ? 281 LYS B C 1 ATOM 5366 O O . LYS B 2 249 ? 83.205 -9.474 10.427 1.00 61.90 ? 281 LYS B O 1 ATOM 5367 C CB . LYS B 2 249 ? 85.432 -11.743 9.193 1.00 61.68 ? 281 LYS B CB 1 ATOM 5368 C CG . LYS B 2 249 ? 86.509 -12.744 9.637 1.00 66.62 ? 281 LYS B CG 1 ATOM 5369 C CD . LYS B 2 249 ? 87.917 -12.439 9.096 1.00 68.21 ? 281 LYS B CD 1 ATOM 5370 C CE . LYS B 2 249 ? 88.044 -12.489 7.565 1.00 70.26 ? 281 LYS B CE 1 ATOM 5371 N NZ . LYS B 2 249 ? 88.278 -13.854 6.989 1.00 67.68 1 281 LYS B NZ 1 ATOM 5372 N N . TYR B 2 250 ? 82.504 -10.633 8.638 1.00 59.11 ? 282 TYR B N 1 ATOM 5373 C CA . TYR B 2 250 ? 81.718 -9.529 8.062 1.00 57.47 ? 282 TYR B CA 1 ATOM 5374 C C . TYR B 2 250 ? 80.224 -9.523 8.441 1.00 56.46 ? 282 TYR B C 1 ATOM 5375 O O . TYR B 2 250 ? 79.393 -9.031 7.663 1.00 54.35 ? 282 TYR B O 1 ATOM 5376 C CB . TYR B 2 250 ? 81.864 -9.555 6.532 1.00 59.08 ? 282 TYR B CB 1 ATOM 5377 C CG . TYR B 2 250 ? 83.257 -9.200 6.056 1.00 62.42 ? 282 TYR B CG 1 ATOM 5378 C CD1 . TYR B 2 250 ? 83.562 -7.900 5.643 1.00 61.51 ? 282 TYR B CD1 1 ATOM 5379 C CD2 . TYR B 2 250 ? 84.277 -10.161 6.030 1.00 64.80 ? 282 TYR B CD2 1 ATOM 5380 C CE1 . TYR B 2 250 ? 84.832 -7.572 5.219 1.00 62.03 ? 282 TYR B CE1 1 ATOM 5381 C CE2 . TYR B 2 250 ? 85.556 -9.838 5.604 1.00 64.73 ? 282 TYR B CE2 1 ATOM 5382 C CZ . TYR B 2 250 ? 85.821 -8.540 5.204 1.00 65.18 ? 282 TYR B CZ 1 ATOM 5383 O OH . TYR B 2 250 ? 87.076 -8.196 4.786 1.00 69.61 ? 282 TYR B OH 1 ATOM 5384 N N . SER B 2 251 ? 79.883 -10.031 9.631 1.00 54.25 ? 283 SER B N 1 ATOM 5385 C CA . SER B 2 251 ? 78.465 -10.218 10.016 1.00 52.35 ? 283 SER B CA 1 ATOM 5386 C C . SER B 2 251 ? 77.729 -8.896 10.213 1.00 52.30 ? 283 SER B C 1 ATOM 5387 O O . SER B 2 251 ? 76.507 -8.817 10.038 1.00 47.38 ? 283 SER B O 1 ATOM 5388 C CB . SER B 2 251 ? 78.316 -11.123 11.262 1.00 51.60 ? 283 SER B CB 1 ATOM 5389 O OG . SER B 2 251 ? 78.479 -10.416 12.480 1.00 50.82 ? 283 SER B OG 1 ATOM 5390 N N . ASP B 2 252 ? 78.487 -7.864 10.576 1.00 57.35 ? 284 ASP B N 1 ATOM 5391 C CA . ASP B 2 252 ? 77.945 -6.506 10.732 1.00 60.18 ? 284 ASP B CA 1 ATOM 5392 C C . ASP B 2 252 ? 77.396 -5.958 9.405 1.00 56.32 ? 284 ASP B C 1 ATOM 5393 O O . ASP B 2 252 ? 76.508 -5.116 9.413 1.00 54.07 ? 284 ASP B O 1 ATOM 5394 C CB . ASP B 2 252 ? 78.981 -5.544 11.368 1.00 63.80 ? 284 ASP B CB 1 ATOM 5395 C CG . ASP B 2 252 ? 80.432 -5.877 10.975 1.00 68.71 ? 284 ASP B CG 1 ATOM 5396 O OD1 . ASP B 2 252 ? 81.003 -6.839 11.554 1.00 65.95 ? 284 ASP B OD1 1 ATOM 5397 O OD2 . ASP B 2 252 ? 80.993 -5.178 10.094 1.00 69.22 -1 284 ASP B OD2 1 ATOM 5398 N N . VAL B 2 253 ? 77.896 -6.463 8.276 1.00 57.75 ? 285 VAL B N 1 ATOM 5399 C CA . VAL B 2 253 ? 77.444 -6.016 6.940 1.00 57.20 ? 285 VAL B CA 1 ATOM 5400 C C . VAL B 2 253 ? 76.269 -6.832 6.388 1.00 56.18 ? 285 VAL B C 1 ATOM 5401 O O . VAL B 2 253 ? 75.371 -6.263 5.753 1.00 57.19 ? 285 VAL B O 1 ATOM 5402 C CB . VAL B 2 253 ? 78.561 -6.092 5.875 1.00 55.56 ? 285 VAL B CB 1 ATOM 5403 C CG1 . VAL B 2 253 ? 78.225 -5.162 4.716 1.00 53.14 ? 285 VAL B CG1 1 ATOM 5404 C CG2 . VAL B 2 253 ? 79.919 -5.739 6.475 1.00 57.43 ? 285 VAL B CG2 1 ATOM 5405 N N . ILE B 2 254 ? 76.295 -8.152 6.612 1.00 51.51 ? 286 ILE B N 1 ATOM 5406 C CA . ILE B 2 254 ? 75.269 -9.058 6.099 1.00 48.06 ? 286 ILE B CA 1 ATOM 5407 C C . ILE B 2 254 ? 74.037 -8.957 7.007 1.00 48.38 ? 286 ILE B C 1 ATOM 5408 O O . ILE B 2 254 ? 74.137 -9.170 8.213 1.00 53.32 ? 286 ILE B O 1 ATOM 5409 C CB . ILE B 2 254 ? 75.730 -10.536 6.075 1.00 48.45 ? 286 ILE B CB 1 ATOM 5410 C CG1 . ILE B 2 254 ? 77.150 -10.703 5.529 1.00 49.31 ? 286 ILE B CG1 1 ATOM 5411 C CG2 . ILE B 2 254 ? 74.776 -11.385 5.244 1.00 48.32 ? 286 ILE B CG2 1 ATOM 5412 C CD1 . ILE B 2 254 ? 77.712 -12.097 5.755 1.00 48.44 ? 286 ILE B CD1 1 ATOM 5413 N N . ALA B 2 255 ? 72.883 -8.636 6.431 1.00 46.36 ? 287 ALA B N 1 ATOM 5414 C CA . ALA B 2 255 ? 71.663 -8.398 7.190 1.00 45.94 ? 287 ALA B CA 1 ATOM 5415 C C . ALA B 2 255 ? 70.608 -9.492 6.964 1.00 47.16 ? 287 ALA B C 1 ATOM 5416 O O . ALA B 2 255 ? 69.413 -9.291 7.236 1.00 51.26 ? 287 ALA B O 1 ATOM 5417 C CB . ALA B 2 255 ? 71.105 -7.038 6.808 1.00 47.02 ? 287 ALA B CB 1 ATOM 5418 N N . GLY B 2 256 ? 71.065 -10.650 6.489 1.00 46.93 ? 288 GLY B N 1 ATOM 5419 C CA . GLY B 2 256 ? 70.199 -11.755 6.054 1.00 44.17 ? 288 GLY B CA 1 ATOM 5420 C C . GLY B 2 256 ? 70.941 -12.552 5.002 1.00 41.65 ? 288 GLY B C 1 ATOM 5421 O O . GLY B 2 256 ? 71.660 -11.984 4.194 1.00 39.94 ? 288 GLY B O 1 ATOM 5422 N N . GLN B 2 257 ? 70.817 -13.870 5.028 1.00 41.83 ? 289 GLN B N 1 ATOM 5423 C CA . GLN B 2 257 ? 71.374 -14.707 3.967 1.00 41.36 ? 289 GLN B CA 1 ATOM 5424 C C . GLN B 2 257 ? 70.264 -15.613 3.502 1.00 44.37 ? 289 GLN B C 1 ATOM 5425 O O . GLN B 2 257 ? 69.389 -15.968 4.306 1.00 46.52 ? 289 GLN B O 1 ATOM 5426 C CB . GLN B 2 257 ? 72.534 -15.542 4.465 1.00 40.53 ? 289 GLN B CB 1 ATOM 5427 C CG . GLN B 2 257 ? 73.708 -14.735 4.986 1.00 42.87 ? 289 GLN B CG 1 ATOM 5428 C CD . GLN B 2 257 ? 74.835 -15.611 5.552 1.00 44.83 ? 289 GLN B CD 1 ATOM 5429 O OE1 . GLN B 2 257 ? 74.997 -16.778 5.166 1.00 44.82 ? 289 GLN B OE1 1 ATOM 5430 N NE2 . GLN B 2 257 ? 75.619 -15.048 6.476 1.00 45.59 ? 289 GLN B NE2 1 ATOM 5431 N N . PHE B 2 258 ? 70.290 -15.993 2.218 1.00 44.97 ? 290 PHE B N 1 ATOM 5432 C CA . PHE B 2 258 ? 69.140 -16.680 1.588 1.00 45.28 ? 290 PHE B CA 1 ATOM 5433 C C . PHE B 2 258 ? 69.478 -17.842 0.599 1.00 45.39 ? 290 PHE B C 1 ATOM 5434 O O . PHE B 2 258 ? 70.137 -17.646 -0.435 1.00 48.71 ? 290 PHE B O 1 ATOM 5435 C CB . PHE B 2 258 ? 68.222 -15.638 0.933 1.00 42.24 ? 290 PHE B CB 1 ATOM 5436 C CG . PHE B 2 258 ? 67.898 -14.454 1.822 1.00 39.50 ? 290 PHE B CG 1 ATOM 5437 C CD1 . PHE B 2 258 ? 66.679 -14.357 2.456 1.00 39.96 ? 290 PHE B CD1 1 ATOM 5438 C CD2 . PHE B 2 258 ? 68.807 -13.428 2.002 1.00 37.37 ? 290 PHE B CD2 1 ATOM 5439 C CE1 . PHE B 2 258 ? 66.361 -13.252 3.244 1.00 40.02 ? 290 PHE B CE1 1 ATOM 5440 C CE2 . PHE B 2 258 ? 68.507 -12.346 2.805 1.00 38.04 ? 290 PHE B CE2 1 ATOM 5441 C CZ . PHE B 2 258 ? 67.281 -12.254 3.430 1.00 38.34 ? 290 PHE B CZ 1 ATOM 5442 N N . TYR B 2 259 ? 68.962 -19.033 0.930 1.00 42.28 ? 291 TYR B N 1 ATOM 5443 C CA . TYR B 2 259 ? 69.274 -20.293 0.255 1.00 38.99 ? 291 TYR B CA 1 ATOM 5444 C C . TYR B 2 259 ? 68.030 -21.190 -0.089 1.00 40.46 ? 291 TYR B C 1 ATOM 5445 O O . TYR B 2 259 ? 66.904 -20.946 0.371 1.00 39.65 ? 291 TYR B O 1 ATOM 5446 C CB . TYR B 2 259 ? 70.207 -21.092 1.147 1.00 36.38 ? 291 TYR B CB 1 ATOM 5447 C CG . TYR B 2 259 ? 71.346 -20.312 1.770 1.00 35.27 ? 291 TYR B CG 1 ATOM 5448 C CD1 . TYR B 2 259 ? 72.489 -20.056 1.049 1.00 36.94 ? 291 TYR B CD1 1 ATOM 5449 C CD2 . TYR B 2 259 ? 71.303 -19.878 3.094 1.00 33.48 ? 291 TYR B CD2 1 ATOM 5450 C CE1 . TYR B 2 259 ? 73.570 -19.374 1.609 1.00 36.72 ? 291 TYR B CE1 1 ATOM 5451 C CE2 . TYR B 2 259 ? 72.384 -19.212 3.675 1.00 33.17 ? 291 TYR B CE2 1 ATOM 5452 C CZ . TYR B 2 259 ? 73.521 -18.958 2.921 1.00 34.48 ? 291 TYR B CZ 1 ATOM 5453 O OH . TYR B 2 259 ? 74.616 -18.288 3.413 1.00 30.93 ? 291 TYR B OH 1 ATOM 5454 N N . GLY B 2 260 ? 68.269 -22.207 -0.926 1.00 39.27 ? 292 GLY B N 1 ATOM 5455 C CA . GLY B 2 260 ? 67.295 -23.237 -1.320 1.00 35.52 ? 292 GLY B CA 1 ATOM 5456 C C . GLY B 2 260 ? 68.091 -24.544 -1.271 1.00 37.41 ? 292 GLY B C 1 ATOM 5457 O O . GLY B 2 260 ? 68.771 -24.791 -0.271 1.00 38.04 ? 292 GLY B O 1 ATOM 5458 N N . HIS B 2 261 ? 68.037 -25.360 -2.341 1.00 37.49 ? 293 HIS B N 1 ATOM 5459 C CA . HIS B 2 261 ? 68.770 -26.670 -2.512 1.00 35.16 ? 293 HIS B CA 1 ATOM 5460 C C . HIS B 2 261 ? 68.152 -27.753 -1.681 1.00 33.13 ? 293 HIS B C 1 ATOM 5461 O O . HIS B 2 261 ? 67.863 -28.798 -2.205 1.00 33.91 ? 293 HIS B O 1 ATOM 5462 C CB . HIS B 2 261 ? 70.317 -26.601 -2.310 1.00 36.91 ? 293 HIS B CB 1 ATOM 5463 C CG . HIS B 2 261 ? 71.028 -27.946 -2.313 1.00 41.25 ? 293 HIS B CG 1 ATOM 5464 N ND1 . HIS B 2 261 ? 70.974 -28.838 -3.366 1.00 42.09 ? 293 HIS B ND1 1 ATOM 5465 C CD2 . HIS B 2 261 ? 71.860 -28.522 -1.396 1.00 44.44 ? 293 HIS B CD2 1 ATOM 5466 C CE1 . HIS B 2 261 ? 71.698 -29.915 -3.082 1.00 42.58 ? 293 HIS B CE1 1 ATOM 5467 N NE2 . HIS B 2 261 ? 72.250 -29.747 -1.893 1.00 42.88 ? 293 HIS B NE2 1 ATOM 5468 N N . THR B 2 262 ? 67.935 -27.516 -0.396 1.00 33.38 ? 294 THR B N 1 ATOM 5469 C CA . THR B 2 262 ? 67.309 -28.525 0.475 1.00 34.09 ? 294 THR B CA 1 ATOM 5470 C C . THR B 2 262 ? 65.867 -28.875 0.167 1.00 34.00 ? 294 THR B C 1 ATOM 5471 O O . THR B 2 262 ? 65.426 -29.949 0.602 1.00 33.83 ? 294 THR B O 1 ATOM 5472 C CB . THR B 2 262 ? 67.287 -28.089 1.951 1.00 36.20 ? 294 THR B CB 1 ATOM 5473 O OG1 . THR B 2 262 ? 66.354 -27.002 2.136 1.00 35.02 ? 294 THR B OG1 1 ATOM 5474 C CG2 . THR B 2 262 ? 68.715 -27.708 2.418 1.00 39.21 ? 294 THR B CG2 1 ATOM 5475 N N . HIS B 2 263 ? 65.151 -27.966 -0.536 1.00 32.55 ? 295 HIS B N 1 ATOM 5476 C CA . HIS B 2 263 ? 63.706 -28.085 -0.872 1.00 31.63 ? 295 HIS B CA 1 ATOM 5477 C C . HIS B 2 263 ? 62.791 -27.953 0.350 1.00 33.06 ? 295 HIS B C 1 ATOM 5478 O O . HIS B 2 263 ? 61.592 -28.312 0.286 1.00 32.96 ? 295 HIS B O 1 ATOM 5479 C CB . HIS B 2 263 ? 63.383 -29.397 -1.590 1.00 29.59 ? 295 HIS B CB 1 ATOM 5480 C CG . HIS B 2 263 ? 63.739 -29.375 -3.022 1.00 29.81 ? 295 HIS B CG 1 ATOM 5481 N ND1 . HIS B 2 263 ? 62.964 -29.977 -3.988 1.00 31.36 ? 295 HIS B ND1 1 ATOM 5482 C CD2 . HIS B 2 263 ? 64.757 -28.770 -3.677 1.00 30.35 ? 295 HIS B CD2 1 ATOM 5483 C CE1 . HIS B 2 263 ? 63.509 -29.778 -5.175 1.00 30.08 ? 295 HIS B CE1 1 ATOM 5484 N NE2 . HIS B 2 263 ? 64.594 -29.040 -5.016 1.00 29.77 ? 295 HIS B NE2 1 ATOM 5485 N N . ARG B 2 264 ? 63.350 -27.394 1.432 1.00 31.54 ? 296 ARG B N 1 ATOM 5486 C CA . ARG B 2 264 ? 62.754 -27.481 2.764 1.00 29.47 ? 296 ARG B CA 1 ATOM 5487 C C . ARG B 2 264 ? 62.782 -26.122 3.472 1.00 27.79 ? 296 ARG B C 1 ATOM 5488 O O . ARG B 2 264 ? 63.632 -25.281 3.175 1.00 25.03 ? 296 ARG B O 1 ATOM 5489 C CB . ARG B 2 264 ? 63.524 -28.547 3.580 1.00 28.45 ? 296 ARG B CB 1 ATOM 5490 C CG . ARG B 2 264 ? 63.516 -29.969 2.991 1.00 26.46 ? 296 ARG B CG 1 ATOM 5491 C CD . ARG B 2 264 ? 62.279 -30.718 3.452 1.00 26.66 ? 296 ARG B CD 1 ATOM 5492 N NE . ARG B 2 264 ? 62.155 -32.044 2.860 1.00 25.54 ? 296 ARG B NE 1 ATOM 5493 C CZ . ARG B 2 264 ? 61.612 -32.306 1.681 1.00 23.03 ? 296 ARG B CZ 1 ATOM 5494 N NH1 . ARG B 2 264 ? 61.138 -31.328 0.944 1.00 23.35 1 296 ARG B NH1 1 ATOM 5495 N NH2 . ARG B 2 264 ? 61.558 -33.554 1.240 1.00 21.91 ? 296 ARG B NH2 1 ATOM 5496 N N . ASP B 2 265 ? 61.851 -25.920 4.399 1.00 28.86 ? 297 ASP B N 1 ATOM 5497 C CA . ASP B 2 265 ? 61.823 -24.689 5.225 1.00 32.19 ? 297 ASP B CA 1 ATOM 5498 C C . ASP B 2 265 ? 62.660 -24.754 6.548 1.00 31.52 ? 297 ASP B C 1 ATOM 5499 O O . ASP B 2 265 ? 62.293 -25.399 7.547 1.00 30.46 ? 297 ASP B O 1 ATOM 5500 C CB . ASP B 2 265 ? 60.373 -24.277 5.524 1.00 33.51 ? 297 ASP B CB 1 ATOM 5501 C CG . ASP B 2 265 ? 60.277 -22.925 6.241 1.00 35.05 ? 297 ASP B CG 1 ATOM 5502 O OD1 . ASP B 2 265 ? 61.248 -22.529 6.945 1.00 33.90 ? 297 ASP B OD1 1 ATOM 5503 O OD2 . ASP B 2 265 ? 59.221 -22.260 6.093 1.00 36.73 -1 297 ASP B OD2 1 ATOM 5504 N N . SER B 2 266 ? 63.768 -24.034 6.557 1.00 30.66 ? 298 SER B N 1 ATOM 5505 C CA . SER B 2 266 ? 64.736 -24.193 7.620 1.00 32.97 ? 298 SER B CA 1 ATOM 5506 C C . SER B 2 266 ? 65.357 -22.867 8.063 1.00 34.01 ? 298 SER B C 1 ATOM 5507 O O . SER B 2 266 ? 65.820 -22.132 7.197 1.00 37.95 ? 298 SER B O 1 ATOM 5508 C CB . SER B 2 266 ? 65.839 -25.118 7.117 1.00 32.98 ? 298 SER B CB 1 ATOM 5509 O OG . SER B 2 266 ? 65.601 -26.457 7.519 1.00 35.55 ? 298 SER B OG 1 ATOM 5510 N N . ILE B 2 267 ? 65.394 -22.551 9.368 1.00 31.68 ? 299 ILE B N 1 ATOM 5511 C CA . ILE B 2 267 ? 66.191 -21.415 9.778 1.00 32.74 ? 299 ILE B CA 1 ATOM 5512 C C . ILE B 2 267 ? 67.518 -21.932 10.306 1.00 33.57 ? 299 ILE B C 1 ATOM 5513 O O . ILE B 2 267 ? 67.631 -23.103 10.708 1.00 36.25 ? 299 ILE B O 1 ATOM 5514 C CB . ILE B 2 267 ? 65.495 -20.472 10.771 1.00 35.48 ? 299 ILE B CB 1 ATOM 5515 C CG1 . ILE B 2 267 ? 65.427 -21.105 12.145 1.00 41.00 ? 299 ILE B CG1 1 ATOM 5516 C CG2 . ILE B 2 267 ? 64.095 -20.099 10.290 1.00 33.81 ? 299 ILE B CG2 1 ATOM 5517 C CD1 . ILE B 2 267 ? 64.771 -20.196 13.162 1.00 44.33 ? 299 ILE B CD1 1 ATOM 5518 N N . MET B 2 268 ? 68.533 -21.068 10.218 1.00 32.76 ? 300 MET B N 1 ATOM 5519 C CA . MET B 2 268 ? 69.865 -21.282 10.812 1.00 30.26 ? 300 MET B CA 1 ATOM 5520 C C . MET B 2 268 ? 70.364 -19.926 11.329 1.00 30.04 ? 300 MET B C 1 ATOM 5521 O O . MET B 2 268 ? 69.848 -18.858 10.952 1.00 27.46 ? 300 MET B O 1 ATOM 5522 C CB . MET B 2 268 ? 70.876 -21.819 9.802 1.00 29.48 ? 300 MET B CB 1 ATOM 5523 C CG . MET B 2 268 ? 70.936 -23.320 9.598 1.00 28.63 ? 300 MET B CG 1 ATOM 5524 S SD . MET B 2 268 ? 72.306 -23.665 8.434 1.00 28.49 ? 300 MET B SD 1 ATOM 5525 C CE . MET B 2 268 ? 71.682 -23.133 6.834 1.00 29.49 ? 300 MET B CE 1 ATOM 5526 N N . VAL B 2 269 ? 71.386 -20.006 12.179 1.00 31.10 ? 301 VAL B N 1 ATOM 5527 C CA . VAL B 2 269 ? 71.860 -18.893 12.983 1.00 31.76 ? 301 VAL B CA 1 ATOM 5528 C C . VAL B 2 269 ? 73.352 -19.025 13.116 1.00 33.76 ? 301 VAL B C 1 ATOM 5529 O O . VAL B 2 269 ? 73.859 -19.980 13.724 1.00 36.16 ? 301 VAL B O 1 ATOM 5530 C CB . VAL B 2 269 ? 71.287 -18.920 14.418 1.00 31.92 ? 301 VAL B CB 1 ATOM 5531 C CG1 . VAL B 2 269 ? 71.749 -17.683 15.192 1.00 31.72 ? 301 VAL B CG1 1 ATOM 5532 C CG2 . VAL B 2 269 ? 69.760 -19.028 14.395 1.00 31.90 ? 301 VAL B CG2 1 ATOM 5533 N N . LEU B 2 270 ? 74.060 -18.060 12.553 1.00 34.74 ? 302 LEU B N 1 ATOM 5534 C CA . LEU B 2 270 ? 75.508 -18.025 12.648 1.00 34.79 ? 302 LEU B CA 1 ATOM 5535 C C . LEU B 2 270 ? 75.822 -17.447 14.000 1.00 36.21 ? 302 LEU B C 1 ATOM 5536 O O . LEU B 2 270 ? 75.263 -16.413 14.365 1.00 36.17 ? 302 LEU B O 1 ATOM 5537 C CB . LEU B 2 270 ? 76.058 -17.134 11.529 1.00 33.69 ? 302 LEU B CB 1 ATOM 5538 C CG . LEU B 2 270 ? 77.555 -16.876 11.413 1.00 32.93 ? 302 LEU B CG 1 ATOM 5539 C CD1 . LEU B 2 270 ? 78.352 -18.172 11.420 1.00 32.18 ? 302 LEU B CD1 1 ATOM 5540 C CD2 . LEU B 2 270 ? 77.779 -16.073 10.139 1.00 33.27 ? 302 LEU B CD2 1 ATOM 5541 N N . SER B 2 271 ? 76.667 -18.118 14.771 1.00 40.10 ? 303 SER B N 1 ATOM 5542 C CA . SER B 2 271 ? 77.236 -17.473 15.964 1.00 44.25 ? 303 SER B CA 1 ATOM 5543 C C . SER B 2 271 ? 78.676 -16.990 15.676 1.00 46.79 ? 303 SER B C 1 ATOM 5544 O O . SER B 2 271 ? 79.318 -17.453 14.740 1.00 48.82 ? 303 SER B O 1 ATOM 5545 C CB . SER B 2 271 ? 77.145 -18.402 17.187 1.00 44.80 ? 303 SER B CB 1 ATOM 5546 O OG . SER B 2 271 ? 75.795 -18.530 17.645 1.00 43.19 ? 303 SER B OG 1 ATOM 5547 N N . ASP B 2 272 ? 79.163 -16.018 16.439 1.00 52.45 ? 304 ASP B N 1 ATOM 5548 C CA . ASP B 2 272 ? 80.543 -15.551 16.270 1.00 55.73 ? 304 ASP B CA 1 ATOM 5549 C C . ASP B 2 272 ? 81.481 -16.558 16.944 1.00 59.77 ? 304 ASP B C 1 ATOM 5550 O O . ASP B 2 272 ? 81.021 -17.497 17.615 1.00 58.11 ? 304 ASP B O 1 ATOM 5551 C CB . ASP B 2 272 ? 80.746 -14.116 16.808 1.00 57.27 ? 304 ASP B CB 1 ATOM 5552 C CG . ASP B 2 272 ? 80.518 -13.991 18.331 1.00 59.79 ? 304 ASP B CG 1 ATOM 5553 O OD1 . ASP B 2 272 ? 80.437 -15.016 19.034 1.00 59.95 ? 304 ASP B OD1 1 ATOM 5554 O OD2 . ASP B 2 272 ? 80.413 -12.851 18.837 1.00 64.95 -1 304 ASP B OD2 1 ATOM 5555 N N . LYS B 2 273 ? 82.786 -16.359 16.755 1.00 63.75 ? 305 LYS B N 1 ATOM 5556 C CA . LYS B 2 273 ? 83.823 -17.235 17.324 1.00 64.17 ? 305 LYS B CA 1 ATOM 5557 C C . LYS B 2 273 ? 83.675 -17.457 18.841 1.00 64.40 ? 305 LYS B C 1 ATOM 5558 O O . LYS B 2 273 ? 83.954 -18.545 19.348 1.00 63.03 ? 305 LYS B O 1 ATOM 5559 C CB . LYS B 2 273 ? 85.203 -16.660 16.997 1.00 66.23 ? 305 LYS B CB 1 ATOM 5560 C CG . LYS B 2 273 ? 85.584 -16.765 15.523 1.00 68.82 ? 305 LYS B CG 1 ATOM 5561 C CD . LYS B 2 273 ? 86.423 -18.015 15.285 1.00 71.44 ? 305 LYS B CD 1 ATOM 5562 C CE . LYS B 2 273 ? 86.544 -18.386 13.814 1.00 75.17 ? 305 LYS B CE 1 ATOM 5563 N NZ . LYS B 2 273 ? 87.342 -17.428 12.997 1.00 77.14 1 305 LYS B NZ 1 ATOM 5564 N N . LYS B 2 274 ? 83.231 -16.416 19.547 1.00 68.40 ? 306 LYS B N 1 ATOM 5565 C CA . LYS B 2 274 ? 82.934 -16.483 20.985 1.00 70.90 ? 306 LYS B CA 1 ATOM 5566 C C . LYS B 2 274 ? 81.803 -17.485 21.269 1.00 67.79 ? 306 LYS B C 1 ATOM 5567 O O . LYS B 2 274 ? 81.947 -18.330 22.136 1.00 73.64 ? 306 LYS B O 1 ATOM 5568 C CB . LYS B 2 274 ? 82.541 -15.091 21.537 1.00 75.88 ? 306 LYS B CB 1 ATOM 5569 C CG . LYS B 2 274 ? 83.378 -14.580 22.712 1.00 77.22 ? 306 LYS B CG 1 ATOM 5570 C CD . LYS B 2 274 ? 84.493 -13.644 22.255 1.00 80.51 ? 306 LYS B CD 1 ATOM 5571 C CE . LYS B 2 274 ? 85.735 -14.389 21.782 1.00 81.48 ? 306 LYS B CE 1 ATOM 5572 N NZ . LYS B 2 274 ? 86.616 -14.767 22.922 1.00 81.34 1 306 LYS B NZ 1 ATOM 5573 N N . GLY B 2 275 ? 80.698 -17.389 20.526 1.00 65.15 ? 307 GLY B N 1 ATOM 5574 C CA . GLY B 2 275 ? 79.490 -18.206 20.761 1.00 60.09 ? 307 GLY B CA 1 ATOM 5575 C C . GLY B 2 275 ? 78.163 -17.443 20.783 1.00 57.71 ? 307 GLY B C 1 ATOM 5576 O O . GLY B 2 275 ? 77.119 -18.037 21.038 1.00 55.51 ? 307 GLY B O 1 ATOM 5577 N N . SER B 2 276 ? 78.193 -16.137 20.504 1.00 56.16 ? 308 SER B N 1 ATOM 5578 C CA . SER B 2 276 ? 76.990 -15.287 20.504 1.00 53.17 ? 308 SER B CA 1 ATOM 5579 C C . SER B 2 276 ? 76.429 -15.020 19.090 1.00 49.80 ? 308 SER B C 1 ATOM 5580 O O . SER B 2 276 ? 77.168 -14.642 18.197 1.00 47.30 ? 308 SER B O 1 ATOM 5581 C CB . SER B 2 276 ? 77.295 -13.951 21.195 1.00 53.27 ? 308 SER B CB 1 ATOM 5582 O OG . SER B 2 276 ? 77.342 -14.113 22.606 1.00 54.49 ? 308 SER B OG 1 ATOM 5583 N N . PRO B 2 277 ? 75.107 -15.177 18.900 1.00 48.76 ? 309 PRO B N 1 ATOM 5584 C CA . PRO B 2 277 ? 74.460 -15.104 17.587 1.00 46.43 ? 309 PRO B CA 1 ATOM 5585 C C . PRO B 2 277 ? 74.676 -13.797 16.852 1.00 44.04 ? 309 PRO B C 1 ATOM 5586 O O . PRO B 2 277 ? 74.397 -12.754 17.415 1.00 42.08 ? 309 PRO B O 1 ATOM 5587 C CB . PRO B 2 277 ? 72.976 -15.221 17.934 1.00 49.17 ? 309 PRO B CB 1 ATOM 5588 C CG . PRO B 2 277 ? 72.864 -14.755 19.349 1.00 49.89 ? 309 PRO B CG 1 ATOM 5589 C CD . PRO B 2 277 ? 74.110 -15.285 19.982 1.00 50.83 ? 309 PRO B CD 1 ATOM 5590 N N . VAL B 2 278 ? 75.128 -13.858 15.595 1.00 44.41 ? 310 VAL B N 1 ATOM 5591 C CA . VAL B 2 278 ? 75.425 -12.644 14.798 1.00 42.77 ? 310 VAL B CA 1 ATOM 5592 C C . VAL B 2 278 ? 74.756 -12.521 13.414 1.00 41.09 ? 310 VAL B C 1 ATOM 5593 O O . VAL B 2 278 ? 74.534 -11.404 12.965 1.00 42.03 ? 310 VAL B O 1 ATOM 5594 C CB . VAL B 2 278 ? 76.956 -12.416 14.617 1.00 43.24 ? 310 VAL B CB 1 ATOM 5595 C CG1 . VAL B 2 278 ? 77.635 -12.221 15.963 1.00 42.10 ? 310 VAL B CG1 1 ATOM 5596 C CG2 . VAL B 2 278 ? 77.624 -13.549 13.835 1.00 43.24 ? 310 VAL B CG2 1 ATOM 5597 N N . ASN B 2 279 ? 74.448 -13.634 12.738 1.00 40.21 ? 311 ASN B N 1 ATOM 5598 C CA . ASN B 2 279 ? 73.828 -13.599 11.387 1.00 39.37 ? 311 ASN B CA 1 ATOM 5599 C C . ASN B 2 279 ? 72.620 -14.535 11.269 1.00 39.65 ? 311 ASN B C 1 ATOM 5600 O O . ASN B 2 279 ? 72.670 -15.667 11.756 1.00 40.76 ? 311 ASN B O 1 ATOM 5601 C CB . ASN B 2 279 ? 74.854 -13.984 10.303 1.00 39.09 ? 311 ASN B CB 1 ATOM 5602 C CG . ASN B 2 279 ? 74.745 -13.122 9.060 1.00 37.44 ? 311 ASN B CG 1 ATOM 5603 O OD1 . ASN B 2 279 ? 74.173 -13.528 8.057 1.00 37.86 ? 311 ASN B OD1 1 ATOM 5604 N ND2 . ASN B 2 279 ? 75.267 -11.919 9.139 1.00 34.83 ? 311 ASN B ND2 1 ATOM 5605 N N . SER B 2 280 ? 71.554 -14.055 10.618 1.00 39.75 ? 312 SER B N 1 ATOM 5606 C CA . SER B 2 280 ? 70.331 -14.834 10.376 1.00 38.38 ? 312 SER B CA 1 ATOM 5607 C C . SER B 2 280 ? 70.302 -15.424 8.982 1.00 38.39 ? 312 SER B C 1 ATOM 5608 O O . SER B 2 280 ? 70.312 -14.673 8.005 1.00 37.53 ? 312 SER B O 1 ATOM 5609 C CB . SER B 2 280 ? 69.090 -13.961 10.540 1.00 37.49 ? 312 SER B CB 1 ATOM 5610 O OG . SER B 2 280 ? 68.556 -14.126 11.832 1.00 38.93 ? 312 SER B OG 1 ATOM 5611 N N . LEU B 2 281 ? 70.220 -16.759 8.914 1.00 38.61 ? 313 LEU B N 1 ATOM 5612 C CA . LEU B 2 281 ? 70.092 -17.502 7.652 1.00 39.89 ? 313 LEU B CA 1 ATOM 5613 C C . LEU B 2 281 ? 68.683 -18.101 7.425 1.00 36.46 ? 313 LEU B C 1 ATOM 5614 O O . LEU B 2 281 ? 67.962 -18.431 8.369 1.00 32.48 ? 313 LEU B O 1 ATOM 5615 C CB . LEU B 2 281 ? 71.162 -18.589 7.587 1.00 44.09 ? 313 LEU B CB 1 ATOM 5616 C CG . LEU B 2 281 ? 72.605 -18.050 7.553 1.00 49.79 ? 313 LEU B CG 1 ATOM 5617 C CD1 . LEU B 2 281 ? 73.037 -17.411 8.871 1.00 52.41 ? 313 LEU B CD1 1 ATOM 5618 C CD2 . LEU B 2 281 ? 73.615 -19.127 7.151 1.00 52.14 ? 313 LEU B CD2 1 ATOM 5619 N N . PHE B 2 282 ? 68.301 -18.215 6.153 1.00 35.98 ? 314 PHE B N 1 ATOM 5620 C CA . PHE B 2 282 ? 66.911 -18.533 5.776 1.00 36.12 ? 314 PHE B CA 1 ATOM 5621 C C . PHE B 2 282 ? 66.756 -19.345 4.484 1.00 34.24 ? 314 PHE B C 1 ATOM 5622 O O . PHE B 2 282 ? 66.531 -18.769 3.393 1.00 37.67 ? 314 PHE B O 1 ATOM 5623 C CB . PHE B 2 282 ? 66.113 -17.246 5.604 1.00 35.55 ? 314 PHE B CB 1 ATOM 5624 C CG . PHE B 2 282 ? 66.048 -16.410 6.829 1.00 34.52 ? 314 PHE B CG 1 ATOM 5625 C CD1 . PHE B 2 282 ? 65.061 -16.621 7.765 1.00 35.37 ? 314 PHE B CD1 1 ATOM 5626 C CD2 . PHE B 2 282 ? 66.966 -15.399 7.032 1.00 34.25 ? 314 PHE B CD2 1 ATOM 5627 C CE1 . PHE B 2 282 ? 64.981 -15.826 8.890 1.00 36.35 ? 314 PHE B CE1 1 ATOM 5628 C CE2 . PHE B 2 282 ? 66.901 -14.593 8.144 1.00 34.71 ? 314 PHE B CE2 1 ATOM 5629 C CZ . PHE B 2 282 ? 65.906 -14.806 9.080 1.00 36.10 ? 314 PHE B CZ 1 ATOM 5630 N N . VAL B 2 283 ? 66.803 -20.669 4.633 1.00 29.45 ? 315 VAL B N 1 ATOM 5631 C CA . VAL B 2 283 ? 66.697 -21.594 3.520 1.00 27.87 ? 315 VAL B CA 1 ATOM 5632 C C . VAL B 2 283 ? 65.227 -21.755 3.124 1.00 28.05 ? 315 VAL B C 1 ATOM 5633 O O . VAL B 2 283 ? 64.422 -22.209 3.923 1.00 28.25 ? 315 VAL B O 1 ATOM 5634 C CB . VAL B 2 283 ? 67.243 -22.985 3.900 1.00 27.31 ? 315 VAL B CB 1 ATOM 5635 C CG1 . VAL B 2 283 ? 67.079 -23.951 2.730 1.00 27.05 ? 315 VAL B CG1 1 ATOM 5636 C CG2 . VAL B 2 283 ? 68.694 -22.915 4.396 1.00 26.54 ? 315 VAL B CG2 1 ATOM 5637 N N . ALA B 2 284 ? 64.879 -21.401 1.892 1.00 28.40 ? 316 ALA B N 1 ATOM 5638 C CA . ALA B 2 284 ? 63.503 -21.525 1.407 1.00 29.39 ? 316 ALA B CA 1 ATOM 5639 C C . ALA B 2 284 ? 63.180 -22.890 0.807 1.00 30.96 ? 316 ALA B C 1 ATOM 5640 O O . ALA B 2 284 ? 64.039 -23.517 0.187 1.00 31.81 ? 316 ALA B O 1 ATOM 5641 C CB . ALA B 2 284 ? 63.256 -20.472 0.346 1.00 30.82 ? 316 ALA B CB 1 ATOM 5642 N N . PRO B 2 285 ? 61.916 -23.331 0.921 1.00 33.19 ? 317 PRO B N 1 ATOM 5643 C CA . PRO B 2 285 ? 61.561 -24.553 0.190 1.00 33.80 ? 317 PRO B CA 1 ATOM 5644 C C . PRO B 2 285 ? 61.325 -24.361 -1.331 1.00 33.22 ? 317 PRO B C 1 ATOM 5645 O O . PRO B 2 285 ? 61.226 -23.256 -1.842 1.00 34.36 ? 317 PRO B O 1 ATOM 5646 C CB . PRO B 2 285 ? 60.293 -25.049 0.915 1.00 33.45 ? 317 PRO B CB 1 ATOM 5647 C CG . PRO B 2 285 ? 59.691 -23.823 1.515 1.00 34.11 ? 317 PRO B CG 1 ATOM 5648 C CD . PRO B 2 285 ? 60.767 -22.773 1.660 1.00 33.82 ? 317 PRO B CD 1 ATOM 5649 N N . ALA B 2 286 ? 61.225 -25.469 -2.034 1.00 33.41 ? 318 ALA B N 1 ATOM 5650 C CA . ALA B 2 286 ? 61.013 -25.455 -3.457 1.00 32.90 ? 318 ALA B CA 1 ATOM 5651 C C . ALA B 2 286 ? 59.583 -25.124 -3.842 1.00 32.64 ? 318 ALA B C 1 ATOM 5652 O O . ALA B 2 286 ? 58.667 -25.064 -3.002 1.00 30.67 ? 318 ALA B O 1 ATOM 5653 C CB . ALA B 2 286 ? 61.353 -26.824 -4.012 1.00 33.88 ? 318 ALA B CB 1 ATOM 5654 N N . VAL B 2 287 ? 59.417 -24.944 -5.153 1.00 32.74 ? 319 VAL B N 1 ATOM 5655 C CA . VAL B 2 287 ? 58.100 -24.931 -5.819 1.00 31.07 ? 319 VAL B CA 1 ATOM 5656 C C . VAL B 2 287 ? 57.668 -26.354 -6.212 1.00 28.26 ? 319 VAL B C 1 ATOM 5657 O O . VAL B 2 287 ? 56.489 -26.704 -6.123 1.00 25.69 ? 319 VAL B O 1 ATOM 5658 C CB . VAL B 2 287 ? 58.112 -24.047 -7.083 1.00 31.10 ? 319 VAL B CB 1 ATOM 5659 C CG1 . VAL B 2 287 ? 56.748 -24.110 -7.752 1.00 31.14 ? 319 VAL B CG1 1 ATOM 5660 C CG2 . VAL B 2 287 ? 58.499 -22.606 -6.741 1.00 31.27 ? 319 VAL B CG2 1 ATOM 5661 N N . THR B 2 288 ? 58.637 -27.159 -6.642 1.00 26.62 ? 320 THR B N 1 ATOM 5662 C CA . THR B 2 288 ? 58.395 -28.572 -6.917 1.00 26.08 ? 320 THR B CA 1 ATOM 5663 C C . THR B 2 288 ? 58.098 -29.389 -5.645 1.00 25.22 ? 320 THR B C 1 ATOM 5664 O O . THR B 2 288 ? 58.658 -29.186 -4.564 1.00 22.19 ? 320 THR B O 1 ATOM 5665 C CB . THR B 2 288 ? 59.543 -29.245 -7.756 1.00 26.52 ? 320 THR B CB 1 ATOM 5666 O OG1 . THR B 2 288 ? 59.158 -30.581 -8.143 1.00 25.88 ? 320 THR B OG1 1 ATOM 5667 C CG2 . THR B 2 288 ? 60.851 -29.312 -6.987 1.00 26.17 ? 320 THR B CG2 1 ATOM 5668 N N . PRO B 2 289 ? 57.212 -30.347 -5.798 1.00 26.75 ? 321 PRO B N 1 ATOM 5669 C CA . PRO B 2 289 ? 56.939 -31.285 -4.754 1.00 28.98 ? 321 PRO B CA 1 ATOM 5670 C C . PRO B 2 289 ? 57.752 -32.575 -4.863 1.00 30.20 ? 321 PRO B C 1 ATOM 5671 O O . PRO B 2 289 ? 57.549 -33.503 -4.072 1.00 30.82 ? 321 PRO B O 1 ATOM 5672 C CB . PRO B 2 289 ? 55.442 -31.604 -4.978 1.00 28.43 ? 321 PRO B CB 1 ATOM 5673 C CG . PRO B 2 289 ? 55.131 -31.209 -6.370 1.00 27.57 ? 321 PRO B CG 1 ATOM 5674 C CD . PRO B 2 289 ? 56.370 -30.608 -6.972 1.00 27.47 ? 321 PRO B CD 1 ATOM 5675 N N . VAL B 2 290 ? 58.640 -32.655 -5.841 1.00 31.95 ? 322 VAL B N 1 ATOM 5676 C CA . VAL B 2 290 ? 59.164 -33.955 -6.273 1.00 33.89 ? 322 VAL B CA 1 ATOM 5677 C C . VAL B 2 290 ? 59.887 -34.710 -5.140 1.00 33.65 ? 322 VAL B C 1 ATOM 5678 O O . VAL B 2 290 ? 60.541 -34.079 -4.273 1.00 33.17 ? 322 VAL B O 1 ATOM 5679 C CB . VAL B 2 290 ? 60.082 -33.807 -7.537 1.00 35.16 ? 322 VAL B CB 1 ATOM 5680 C CG1 . VAL B 2 290 ? 61.427 -33.109 -7.214 1.00 33.72 ? 322 VAL B CG1 1 ATOM 5681 C CG2 . VAL B 2 290 ? 60.281 -35.168 -8.223 1.00 34.94 ? 322 VAL B CG2 1 ATOM 5682 N N . LYS B 2 291 ? 59.780 -36.048 -5.173 1.00 32.02 ? 323 LYS B N 1 ATOM 5683 C CA . LYS B 2 291 ? 60.469 -36.938 -4.205 1.00 30.89 ? 323 LYS B CA 1 ATOM 5684 C C . LYS B 2 291 ? 60.723 -38.395 -4.702 1.00 30.47 ? 323 LYS B C 1 ATOM 5685 O O . LYS B 2 291 ? 60.193 -38.809 -5.738 1.00 31.59 ? 323 LYS B O 1 ATOM 5686 C CB . LYS B 2 291 ? 59.698 -36.977 -2.893 1.00 29.45 ? 323 LYS B CB 1 ATOM 5687 C CG . LYS B 2 291 ? 58.295 -37.543 -3.014 1.00 29.47 ? 323 LYS B CG 1 ATOM 5688 C CD . LYS B 2 291 ? 58.065 -38.595 -1.929 1.00 29.87 ? 323 LYS B CD 1 ATOM 5689 C CE . LYS B 2 291 ? 56.756 -39.367 -2.105 1.00 30.19 ? 323 LYS B CE 1 ATOM 5690 N NZ . LYS B 2 291 ? 56.865 -40.816 -1.746 1.00 30.28 1 323 LYS B NZ 1 ATOM 5691 N N . SER B 2 292 ? 61.539 -39.146 -3.954 1.00 29.90 ? 324 SER B N 1 ATOM 5692 C CA A SER B 2 292 ? 61.814 -40.553 -4.261 0.50 30.16 ? 324 SER B CA 1 ATOM 5693 C CA B SER B 2 292 ? 61.817 -40.566 -4.234 0.50 29.44 ? 324 SER B CA 1 ATOM 5694 C C . SER B 2 292 ? 60.664 -41.433 -3.813 1.00 29.64 ? 324 SER B C 1 ATOM 5695 O O . SER B 2 292 ? 59.990 -41.138 -2.839 1.00 31.08 ? 324 SER B O 1 ATOM 5696 C CB A SER B 2 292 ? 63.086 -41.030 -3.559 0.50 31.27 ? 324 SER B CB 1 ATOM 5697 C CB B SER B 2 292 ? 63.049 -41.061 -3.468 0.50 29.75 ? 324 SER B CB 1 ATOM 5698 O OG A SER B 2 292 ? 64.228 -40.294 -3.976 0.50 32.57 ? 324 SER B OG 1 ATOM 5699 O OG B SER B 2 292 ? 62.762 -42.250 -2.733 0.50 29.10 ? 324 SER B OG 1 ATOM 5700 N N . VAL B 2 293 ? 60.477 -42.535 -4.509 1.00 29.16 ? 325 VAL B N 1 ATOM 5701 C CA . VAL B 2 293 ? 59.405 -43.427 -4.173 1.00 29.29 ? 325 VAL B CA 1 ATOM 5702 C C . VAL B 2 293 ? 59.526 -43.890 -2.715 1.00 31.43 ? 325 VAL B C 1 ATOM 5703 O O . VAL B 2 293 ? 58.519 -43.989 -2.004 1.00 34.00 ? 325 VAL B O 1 ATOM 5704 C CB . VAL B 2 293 ? 59.383 -44.611 -5.132 1.00 29.99 ? 325 VAL B CB 1 ATOM 5705 C CG1 . VAL B 2 293 ? 58.309 -45.605 -4.719 1.00 31.20 ? 325 VAL B CG1 1 ATOM 5706 C CG2 . VAL B 2 293 ? 59.153 -44.132 -6.563 1.00 29.93 ? 325 VAL B CG2 1 ATOM 5707 N N . LEU B 2 294 ? 60.753 -44.102 -2.241 1.00 32.69 ? 326 LEU B N 1 ATOM 5708 C CA . LEU B 2 294 ? 60.997 -44.675 -0.886 1.00 32.22 ? 326 LEU B CA 1 ATOM 5709 C C . LEU B 2 294 ? 60.785 -43.720 0.293 1.00 29.37 ? 326 LEU B C 1 ATOM 5710 O O . LEU B 2 294 ? 60.749 -44.136 1.438 1.00 25.80 ? 326 LEU B O 1 ATOM 5711 C CB . LEU B 2 294 ? 62.422 -45.242 -0.831 1.00 33.89 ? 326 LEU B CB 1 ATOM 5712 C CG . LEU B 2 294 ? 62.777 -46.232 -1.967 1.00 34.03 ? 326 LEU B CG 1 ATOM 5713 C CD1 . LEU B 2 294 ? 64.187 -46.792 -1.855 1.00 33.33 ? 326 LEU B CD1 1 ATOM 5714 C CD2 . LEU B 2 294 ? 61.760 -47.368 -1.961 1.00 35.73 ? 326 LEU B CD2 1 ATOM 5715 N N . GLU B 2 295 ? 60.686 -42.443 -0.028 1.00 30.06 ? 327 GLU B N 1 ATOM 5716 C CA . GLU B 2 295 ? 60.545 -41.351 0.907 1.00 30.31 ? 327 GLU B CA 1 ATOM 5717 C C . GLU B 2 295 ? 59.152 -41.082 1.263 1.00 30.55 ? 327 GLU B C 1 ATOM 5718 O O . GLU B 2 295 ? 58.351 -40.928 0.417 1.00 30.42 ? 327 GLU B O 1 ATOM 5719 C CB . GLU B 2 295 ? 61.082 -40.114 0.249 1.00 29.50 ? 327 GLU B CB 1 ATOM 5720 C CG . GLU B 2 295 ? 62.573 -40.140 0.106 1.00 29.95 ? 327 GLU B CG 1 ATOM 5721 C CD . GLU B 2 295 ? 63.114 -38.937 -0.586 1.00 31.02 ? 327 GLU B CD 1 ATOM 5722 O OE1 . GLU B 2 295 ? 64.298 -38.898 -0.877 1.00 32.38 ? 327 GLU B OE1 1 ATOM 5723 O OE2 . GLU B 2 295 ? 62.372 -38.023 -0.863 1.00 31.37 -1 327 GLU B OE2 1 ATOM 5724 N N . LYS B 2 296 ? 58.864 -41.005 2.539 1.00 33.23 ? 328 LYS B N 1 ATOM 5725 C CA . LYS B 2 296 ? 57.514 -40.795 2.994 1.00 36.04 ? 328 LYS B CA 1 ATOM 5726 C C . LYS B 2 296 ? 57.093 -39.405 2.904 1.00 37.08 ? 328 LYS B C 1 ATOM 5727 O O . LYS B 2 296 ? 55.930 -39.132 2.783 1.00 42.85 ? 328 LYS B O 1 ATOM 5728 C CB . LYS B 2 296 ? 57.352 -41.193 4.460 1.00 36.54 ? 328 LYS B CB 1 ATOM 5729 C CG . LYS B 2 296 ? 55.979 -40.903 5.050 1.00 37.80 ? 328 LYS B CG 1 ATOM 5730 C CD . LYS B 2 296 ? 55.584 -41.768 6.237 1.00 39.24 ? 328 LYS B CD 1 ATOM 5731 C CE . LYS B 2 296 ? 56.123 -41.230 7.564 1.00 40.62 ? 328 LYS B CE 1 ATOM 5732 N NZ . LYS B 2 296 ? 55.263 -41.341 8.780 1.00 39.26 1 328 LYS B NZ 1 ATOM 5733 N N . GLN B 2 297 ? 58.056 -38.522 2.996 1.00 36.43 ? 329 GLN B N 1 ATOM 5734 C CA . GLN B 2 297 ? 57.824 -37.109 3.034 1.00 34.92 ? 329 GLN B CA 1 ATOM 5735 C C . GLN B 2 297 ? 58.446 -36.273 1.974 1.00 34.94 ? 329 GLN B C 1 ATOM 5736 O O . GLN B 2 297 ? 59.543 -36.538 1.571 1.00 34.64 ? 329 GLN B O 1 ATOM 5737 C CB . GLN B 2 297 ? 58.523 -36.618 4.284 1.00 34.18 ? 329 GLN B CB 1 ATOM 5738 C CG . GLN B 2 297 ? 57.893 -37.009 5.572 1.00 34.28 ? 329 GLN B CG 1 ATOM 5739 C CD . GLN B 2 297 ? 56.450 -36.702 5.593 1.00 35.10 ? 329 GLN B CD 1 ATOM 5740 O OE1 . GLN B 2 297 ? 55.696 -37.406 6.186 1.00 37.48 ? 329 GLN B OE1 1 ATOM 5741 N NE2 . GLN B 2 297 ? 56.055 -35.674 4.927 1.00 35.64 ? 329 GLN B NE2 1 ATOM 5742 N N . THR B 2 298 ? 57.754 -35.209 1.582 1.00 34.76 ? 330 THR B N 1 ATOM 5743 C CA . THR B 2 298 ? 58.263 -34.171 0.682 1.00 35.82 ? 330 THR B CA 1 ATOM 5744 C C . THR B 2 298 ? 57.675 -32.860 1.122 1.00 36.26 ? 330 THR B C 1 ATOM 5745 O O . THR B 2 298 ? 56.985 -32.849 2.094 1.00 36.56 ? 330 THR B O 1 ATOM 5746 C CB . THR B 2 298 ? 58.059 -34.374 -0.830 1.00 34.75 ? 330 THR B CB 1 ATOM 5747 O OG1 . THR B 2 298 ? 58.916 -33.486 -1.534 1.00 31.91 ? 330 THR B OG1 1 ATOM 5748 C CG2 . THR B 2 298 ? 56.703 -34.085 -1.254 1.00 34.71 ? 330 THR B CG2 1 ATOM 5749 N N . ASN B 2 299 ? 57.820 -31.818 0.357 1.00 35.20 ? 331 ASN B N 1 ATOM 5750 C CA . ASN B 2 299 ? 57.235 -30.575 0.735 1.00 31.84 ? 331 ASN B CA 1 ATOM 5751 C C . ASN B 2 299 ? 56.068 -30.238 -0.120 1.00 30.84 ? 331 ASN B C 1 ATOM 5752 O O . ASN B 2 299 ? 55.867 -30.787 -1.146 1.00 29.81 ? 331 ASN B O 1 ATOM 5753 C CB . ASN B 2 299 ? 58.259 -29.507 0.436 1.00 30.86 ? 331 ASN B CB 1 ATOM 5754 C CG . ASN B 2 299 ? 58.879 -29.680 -0.926 1.00 31.30 ? 331 ASN B CG 1 ATOM 5755 O OD1 . ASN B 2 299 ? 59.324 -30.743 -1.227 1.00 31.66 ? 331 ASN B OD1 1 ATOM 5756 N ND2 . ASN B 2 299 ? 58.870 -28.669 -1.744 1.00 32.52 ? 331 ASN B ND2 1 ATOM 5757 N N . ASN B 2 300 ? 55.277 -29.301 0.307 1.00 28.92 ? 332 ASN B N 1 ATOM 5758 C CA . ASN B 2 300 ? 54.310 -28.754 -0.597 1.00 26.99 ? 332 ASN B CA 1 ATOM 5759 C C . ASN B 2 300 ? 55.050 -27.617 -1.322 1.00 26.44 ? 332 ASN B C 1 ATOM 5760 O O . ASN B 2 300 ? 55.984 -26.995 -0.737 1.00 22.02 ? 332 ASN B O 1 ATOM 5761 C CB . ASN B 2 300 ? 53.066 -28.209 0.121 1.00 26.22 ? 332 ASN B CB 1 ATOM 5762 C CG . ASN B 2 300 ? 52.047 -29.278 0.521 1.00 24.34 ? 332 ASN B CG 1 ATOM 5763 O OD1 . ASN B 2 300 ? 51.539 -29.241 1.634 1.00 24.28 ? 332 ASN B OD1 1 ATOM 5764 N ND2 . ASN B 2 300 ? 51.706 -30.183 -0.386 1.00 23.83 ? 332 ASN B ND2 1 ATOM 5765 N N . PRO B 2 301 ? 54.639 -27.357 -2.595 1.00 27.84 ? 333 PRO B N 1 ATOM 5766 C CA . PRO B 2 301 ? 55.111 -26.199 -3.348 1.00 29.04 ? 333 PRO B CA 1 ATOM 5767 C C . PRO B 2 301 ? 55.014 -24.933 -2.493 1.00 31.46 ? 333 PRO B C 1 ATOM 5768 O O . PRO B 2 301 ? 53.964 -24.663 -1.888 1.00 31.06 ? 333 PRO B O 1 ATOM 5769 C CB . PRO B 2 301 ? 54.155 -26.151 -4.531 1.00 27.35 ? 333 PRO B CB 1 ATOM 5770 C CG . PRO B 2 301 ? 53.810 -27.569 -4.760 1.00 26.79 ? 333 PRO B CG 1 ATOM 5771 C CD . PRO B 2 301 ? 53.655 -28.130 -3.386 1.00 26.98 ? 333 PRO B CD 1 ATOM 5772 N N . GLY B 2 302 ? 56.121 -24.196 -2.422 1.00 32.81 ? 334 GLY B N 1 ATOM 5773 C CA . GLY B 2 302 ? 56.269 -23.133 -1.446 1.00 33.57 ? 334 GLY B CA 1 ATOM 5774 C C . GLY B 2 302 ? 56.926 -21.910 -2.031 1.00 34.10 ? 334 GLY B C 1 ATOM 5775 O O . GLY B 2 302 ? 57.807 -22.013 -2.889 1.00 34.76 ? 334 GLY B O 1 ATOM 5776 N N . ILE B 2 303 ? 56.490 -20.763 -1.526 1.00 33.89 ? 335 ILE B N 1 ATOM 5777 C CA . ILE B 2 303 ? 56.809 -19.452 -2.057 1.00 36.09 ? 335 ILE B CA 1 ATOM 5778 C C . ILE B 2 303 ? 56.806 -18.647 -0.766 1.00 34.01 ? 335 ILE B C 1 ATOM 5779 O O . ILE B 2 303 ? 56.024 -18.977 0.122 1.00 32.72 ? 335 ILE B O 1 ATOM 5780 C CB . ILE B 2 303 ? 55.697 -18.997 -3.097 1.00 39.44 ? 335 ILE B CB 1 ATOM 5781 C CG1 . ILE B 2 303 ? 55.814 -19.735 -4.444 1.00 39.24 ? 335 ILE B CG1 1 ATOM 5782 C CG2 . ILE B 2 303 ? 55.701 -17.503 -3.408 1.00 40.59 ? 335 ILE B CG2 1 ATOM 5783 C CD1 . ILE B 2 303 ? 57.096 -19.485 -5.224 1.00 38.05 ? 335 ILE B CD1 1 ATOM 5784 N N . ARG B 2 304 ? 57.678 -17.646 -0.627 1.00 32.97 ? 336 ARG B N 1 ATOM 5785 C CA . ARG B 2 304 ? 57.646 -16.765 0.545 1.00 33.51 ? 336 ARG B CA 1 ATOM 5786 C C . ARG B 2 304 ? 57.923 -15.311 0.267 1.00 38.24 ? 336 ARG B C 1 ATOM 5787 O O . ARG B 2 304 ? 58.469 -14.922 -0.773 1.00 40.54 ? 336 ARG B O 1 ATOM 5788 C CB . ARG B 2 304 ? 58.652 -17.211 1.577 1.00 32.59 ? 336 ARG B CB 1 ATOM 5789 C CG . ARG B 2 304 ? 60.069 -17.181 1.077 1.00 32.19 ? 336 ARG B CG 1 ATOM 5790 C CD . ARG B 2 304 ? 61.061 -17.554 2.157 1.00 33.81 ? 336 ARG B CD 1 ATOM 5791 N NE . ARG B 2 304 ? 60.746 -18.806 2.859 1.00 36.08 ? 336 ARG B NE 1 ATOM 5792 C CZ . ARG B 2 304 ? 61.595 -19.443 3.673 1.00 40.28 ? 336 ARG B CZ 1 ATOM 5793 N NH1 . ARG B 2 304 ? 62.834 -18.979 3.873 1.00 44.45 1 336 ARG B NH1 1 ATOM 5794 N NH2 . ARG B 2 304 ? 61.225 -20.564 4.291 1.00 40.63 ? 336 ARG B NH2 1 ATOM 5795 N N . LEU B 2 305 ? 57.577 -14.512 1.264 1.00 43.64 ? 337 LEU B N 1 ATOM 5796 C CA . LEU B 2 305 ? 57.693 -13.077 1.196 1.00 44.19 ? 337 LEU B CA 1 ATOM 5797 C C . LEU B 2 305 ? 58.352 -12.521 2.459 1.00 47.54 ? 337 LEU B C 1 ATOM 5798 O O . LEU B 2 305 ? 57.823 -12.660 3.599 1.00 43.85 ? 337 LEU B O 1 ATOM 5799 C CB . LEU B 2 305 ? 56.307 -12.489 1.039 1.00 45.85 ? 337 LEU B CB 1 ATOM 5800 C CG . LEU B 2 305 ? 56.223 -10.982 1.222 1.00 48.66 ? 337 LEU B CG 1 ATOM 5801 C CD1 . LEU B 2 305 ? 57.227 -10.255 0.333 1.00 49.54 ? 337 LEU B CD1 1 ATOM 5802 C CD2 . LEU B 2 305 ? 54.798 -10.566 0.918 1.00 49.67 ? 337 LEU B CD2 1 ATOM 5803 N N . PHE B 2 306 ? 59.499 -11.876 2.231 1.00 49.77 ? 338 PHE B N 1 ATOM 5804 C CA . PHE B 2 306 ? 60.261 -11.200 3.288 1.00 51.63 ? 338 PHE B CA 1 ATOM 5805 C C . PHE B 2 306 ? 59.910 -9.727 3.439 1.00 51.41 ? 338 PHE B C 1 ATOM 5806 O O . PHE B 2 306 ? 59.669 -9.033 2.440 1.00 48.34 ? 338 PHE B O 1 ATOM 5807 C CB . PHE B 2 306 ? 61.774 -11.319 3.048 1.00 51.68 ? 338 PHE B CB 1 ATOM 5808 C CG . PHE B 2 306 ? 62.322 -12.629 3.472 1.00 50.72 ? 338 PHE B CG 1 ATOM 5809 C CD1 . PHE B 2 306 ? 62.636 -12.857 4.804 1.00 50.83 ? 338 PHE B CD1 1 ATOM 5810 C CD2 . PHE B 2 306 ? 62.459 -13.656 2.560 1.00 49.80 ? 338 PHE B CD2 1 ATOM 5811 C CE1 . PHE B 2 306 ? 63.108 -14.096 5.218 1.00 51.31 ? 338 PHE B CE1 1 ATOM 5812 C CE2 . PHE B 2 306 ? 62.929 -14.896 2.960 1.00 51.62 ? 338 PHE B CE2 1 ATOM 5813 C CZ . PHE B 2 306 ? 63.257 -15.119 4.294 1.00 52.53 ? 338 PHE B CZ 1 ATOM 5814 N N . GLN B 2 307 ? 59.909 -9.284 4.705 1.00 50.02 ? 339 GLN B N 1 ATOM 5815 C CA . GLN B 2 307 ? 59.772 -7.884 5.083 1.00 46.57 ? 339 GLN B CA 1 ATOM 5816 C C . GLN B 2 307 ? 61.078 -7.388 5.692 1.00 49.09 ? 339 GLN B C 1 ATOM 5817 O O . GLN B 2 307 ? 61.818 -8.155 6.326 1.00 49.54 ? 339 GLN B O 1 ATOM 5818 C CB . GLN B 2 307 ? 58.622 -7.695 6.074 1.00 43.14 ? 339 GLN B CB 1 ATOM 5819 C CG . GLN B 2 307 ? 57.244 -7.852 5.449 1.00 40.15 ? 339 GLN B CG 1 ATOM 5820 C CD . GLN B 2 307 ? 56.120 -7.654 6.438 1.00 37.24 ? 339 GLN B CD 1 ATOM 5821 O OE1 . GLN B 2 307 ? 56.340 -7.345 7.599 1.00 36.14 ? 339 GLN B OE1 1 ATOM 5822 N NE2 . GLN B 2 307 ? 54.903 -7.842 5.980 1.00 36.49 ? 339 GLN B NE2 1 ATOM 5823 N N . TYR B 2 308 ? 61.351 -6.103 5.466 1.00 52.47 ? 340 TYR B N 1 ATOM 5824 C CA . TYR B 2 308 ? 62.546 -5.439 5.967 1.00 53.96 ? 340 TYR B CA 1 ATOM 5825 C C . TYR B 2 308 ? 62.271 -3.964 6.287 1.00 54.74 ? 340 TYR B C 1 ATOM 5826 O O . TYR B 2 308 ? 61.214 -3.404 5.954 1.00 50.18 ? 340 TYR B O 1 ATOM 5827 C CB . TYR B 2 308 ? 63.718 -5.573 4.975 1.00 54.85 ? 340 TYR B CB 1 ATOM 5828 C CG . TYR B 2 308 ? 63.481 -4.975 3.603 1.00 58.71 ? 340 TYR B CG 1 ATOM 5829 C CD1 . TYR B 2 308 ? 62.794 -5.685 2.612 1.00 59.88 ? 340 TYR B CD1 1 ATOM 5830 C CD2 . TYR B 2 308 ? 63.952 -3.705 3.285 1.00 64.11 ? 340 TYR B CD2 1 ATOM 5831 C CE1 . TYR B 2 308 ? 62.570 -5.148 1.355 1.00 57.66 ? 340 TYR B CE1 1 ATOM 5832 C CE2 . TYR B 2 308 ? 63.732 -3.161 2.023 1.00 66.32 ? 340 TYR B CE2 1 ATOM 5833 C CZ . TYR B 2 308 ? 63.039 -3.892 1.066 1.00 61.34 ? 340 TYR B CZ 1 ATOM 5834 O OH . TYR B 2 308 ? 62.831 -3.361 -0.183 1.00 62.84 ? 340 TYR B OH 1 ATOM 5835 N N . ASP B 2 309 ? 63.234 -3.371 6.976 1.00 54.79 ? 341 ASP B N 1 ATOM 5836 C CA . ASP B 2 309 ? 63.212 -1.982 7.329 1.00 55.39 ? 341 ASP B CA 1 ATOM 5837 C C . ASP B 2 309 ? 64.061 -1.318 6.235 1.00 57.28 ? 341 ASP B C 1 ATOM 5838 O O . ASP B 2 309 ? 65.225 -1.691 6.080 1.00 59.12 ? 341 ASP B O 1 ATOM 5839 C CB . ASP B 2 309 ? 63.821 -1.843 8.733 1.00 57.43 ? 341 ASP B CB 1 ATOM 5840 C CG . ASP B 2 309 ? 63.398 -0.570 9.443 1.00 60.75 ? 341 ASP B CG 1 ATOM 5841 O OD1 . ASP B 2 309 ? 64.004 0.473 9.152 1.00 65.04 ? 341 ASP B OD1 1 ATOM 5842 O OD2 . ASP B 2 309 ? 62.489 -0.602 10.307 1.00 59.14 -1 341 ASP B OD2 1 ATOM 5843 N N . PRO B 2 310 ? 63.483 -0.376 5.438 1.00 57.21 ? 342 PRO B N 1 ATOM 5844 C CA . PRO B 2 310 ? 64.219 0.323 4.356 1.00 57.91 ? 342 PRO B CA 1 ATOM 5845 C C . PRO B 2 310 ? 65.427 1.178 4.794 1.00 57.30 ? 342 PRO B C 1 ATOM 5846 O O . PRO B 2 310 ? 66.286 1.520 3.965 1.00 52.39 ? 342 PRO B O 1 ATOM 5847 C CB . PRO B 2 310 ? 63.149 1.225 3.726 1.00 57.88 ? 342 PRO B CB 1 ATOM 5848 C CG . PRO B 2 310 ? 61.856 0.593 4.063 1.00 57.17 ? 342 PRO B CG 1 ATOM 5849 C CD . PRO B 2 310 ? 62.062 0.007 5.432 1.00 58.55 ? 342 PRO B CD 1 ATOM 5850 N N . ARG B 2 311 ? 65.475 1.529 6.075 1.00 58.66 ? 343 ARG B N 1 ATOM 5851 C CA . ARG B 2 311 ? 66.616 2.232 6.635 1.00 58.55 ? 343 ARG B CA 1 ATOM 5852 C C . ARG B 2 311 ? 67.860 1.339 6.733 1.00 58.17 ? 343 ARG B C 1 ATOM 5853 O O . ARG B 2 311 ? 68.836 1.604 6.043 1.00 59.87 ? 343 ARG B O 1 ATOM 5854 C CB . ARG B 2 311 ? 66.259 2.827 7.997 1.00 61.00 ? 343 ARG B CB 1 ATOM 5855 C CG . ARG B 2 311 ? 65.190 3.919 7.932 1.00 64.05 ? 343 ARG B CG 1 ATOM 5856 C CD . ARG B 2 311 ? 64.835 4.418 9.330 1.00 65.49 ? 343 ARG B CD 1 ATOM 5857 N NE . ARG B 2 311 ? 63.882 3.521 10.000 1.00 66.15 ? 343 ARG B NE 1 ATOM 5858 C CZ . ARG B 2 311 ? 63.775 3.338 11.317 1.00 61.64 ? 343 ARG B CZ 1 ATOM 5859 N NH1 . ARG B 2 311 ? 64.583 3.962 12.174 1.00 60.58 1 343 ARG B NH1 1 ATOM 5860 N NH2 . ARG B 2 311 ? 62.853 2.495 11.779 1.00 59.24 ? 343 ARG B NH2 1 ATOM 5861 N N . ASP B 2 312 ? 67.832 0.288 7.560 1.00 58.14 ? 344 ASP B N 1 ATOM 5862 C CA . ASP B 2 312 ? 69.044 -0.565 7.786 1.00 57.84 ? 344 ASP B CA 1 ATOM 5863 C C . ASP B 2 312 ? 68.972 -1.962 7.139 1.00 54.53 ? 344 ASP B C 1 ATOM 5864 O O . ASP B 2 312 ? 69.929 -2.749 7.230 1.00 46.65 ? 344 ASP B O 1 ATOM 5865 C CB . ASP B 2 312 ? 69.416 -0.671 9.292 1.00 58.96 ? 344 ASP B CB 1 ATOM 5866 C CG . ASP B 2 312 ? 68.208 -0.961 10.204 1.00 62.14 ? 344 ASP B CG 1 ATOM 5867 O OD1 . ASP B 2 312 ? 67.046 -0.686 9.804 1.00 64.31 ? 344 ASP B OD1 1 ATOM 5868 O OD2 . ASP B 2 312 ? 68.429 -1.455 11.336 1.00 62.07 -1 344 ASP B OD2 1 ATOM 5869 N N . TYR B 2 313 ? 67.848 -2.241 6.465 1.00 56.67 ? 345 TYR B N 1 ATOM 5870 C CA . TYR B 2 313 ? 67.582 -3.554 5.828 1.00 57.82 ? 345 TYR B CA 1 ATOM 5871 C C . TYR B 2 313 ? 67.691 -4.685 6.843 1.00 53.49 ? 345 TYR B C 1 ATOM 5872 O O . TYR B 2 313 ? 68.252 -5.748 6.567 1.00 48.05 ? 345 TYR B O 1 ATOM 5873 C CB . TYR B 2 313 ? 68.489 -3.766 4.604 1.00 59.34 ? 345 TYR B CB 1 ATOM 5874 C CG . TYR B 2 313 ? 68.454 -2.561 3.681 1.00 59.30 ? 345 TYR B CG 1 ATOM 5875 C CD1 . TYR B 2 313 ? 67.330 -2.292 2.879 1.00 57.21 ? 345 TYR B CD1 1 ATOM 5876 C CD2 . TYR B 2 313 ? 69.518 -1.662 3.648 1.00 56.93 ? 345 TYR B CD2 1 ATOM 5877 C CE1 . TYR B 2 313 ? 67.292 -1.178 2.064 1.00 54.05 ? 345 TYR B CE1 1 ATOM 5878 C CE2 . TYR B 2 313 ? 69.478 -0.545 2.843 1.00 54.41 ? 345 TYR B CE2 1 ATOM 5879 C CZ . TYR B 2 313 ? 68.375 -0.312 2.060 1.00 54.17 ? 345 TYR B CZ 1 ATOM 5880 O OH . TYR B 2 313 ? 68.387 0.798 1.270 1.00 60.57 ? 345 TYR B OH 1 ATOM 5881 N N . LYS B 2 314 ? 67.147 -4.401 8.026 1.00 52.06 ? 346 LYS B N 1 ATOM 5882 C CA . LYS B 2 314 ? 67.012 -5.356 9.106 1.00 52.65 ? 346 LYS B CA 1 ATOM 5883 C C . LYS B 2 314 ? 65.744 -6.152 8.800 1.00 52.04 ? 346 LYS B C 1 ATOM 5884 O O . LYS B 2 314 ? 64.717 -5.576 8.409 1.00 52.06 ? 346 LYS B O 1 ATOM 5885 C CB . LYS B 2 314 ? 66.909 -4.612 10.446 1.00 53.90 ? 346 LYS B CB 1 ATOM 5886 C CG . LYS B 2 314 ? 66.395 -5.447 11.610 1.00 58.97 ? 346 LYS B CG 1 ATOM 5887 C CD . LYS B 2 314 ? 66.580 -4.732 12.947 1.00 62.84 ? 346 LYS B CD 1 ATOM 5888 C CE . LYS B 2 314 ? 65.596 -5.226 14.002 1.00 62.54 ? 346 LYS B CE 1 ATOM 5889 N NZ . LYS B 2 314 ? 64.301 -4.501 13.860 1.00 64.01 1 346 LYS B NZ 1 ATOM 5890 N N . LEU B 2 315 ? 65.812 -7.471 8.942 1.00 48.39 ? 347 LEU B N 1 ATOM 5891 C CA . LEU B 2 315 ? 64.659 -8.302 8.610 1.00 48.22 ? 347 LEU B CA 1 ATOM 5892 C C . LEU B 2 315 ? 63.541 -8.182 9.670 1.00 46.35 ? 347 LEU B C 1 ATOM 5893 O O . LEU B 2 315 ? 63.756 -8.401 10.866 1.00 47.75 ? 347 LEU B O 1 ATOM 5894 C CB . LEU B 2 315 ? 65.098 -9.758 8.401 1.00 47.84 ? 347 LEU B CB 1 ATOM 5895 C CG . LEU B 2 315 ? 65.882 -10.017 7.118 1.00 47.14 ? 347 LEU B CG 1 ATOM 5896 C CD1 . LEU B 2 315 ? 66.458 -11.419 7.176 1.00 47.09 ? 347 LEU B CD1 1 ATOM 5897 C CD2 . LEU B 2 315 ? 64.997 -9.861 5.888 1.00 48.50 ? 347 LEU B CD2 1 ATOM 5898 N N . LEU B 2 316 ? 62.351 -7.815 9.229 1.00 43.67 ? 348 LEU B N 1 ATOM 5899 C CA . LEU B 2 316 ? 61.244 -7.662 10.149 1.00 44.40 ? 348 LEU B CA 1 ATOM 5900 C C . LEU B 2 316 ? 60.465 -8.929 10.280 1.00 41.37 ? 348 LEU B C 1 ATOM 5901 O O . LEU B 2 316 ? 60.005 -9.237 11.369 1.00 45.35 ? 348 LEU B O 1 ATOM 5902 C CB . LEU B 2 316 ? 60.287 -6.552 9.706 1.00 47.67 ? 348 LEU B CB 1 ATOM 5903 C CG . LEU B 2 316 ? 60.801 -5.111 9.800 1.00 51.16 ? 348 LEU B CG 1 ATOM 5904 C CD1 . LEU B 2 316 ? 59.650 -4.178 9.446 1.00 52.26 ? 348 LEU B CD1 1 ATOM 5905 C CD2 . LEU B 2 316 ? 61.408 -4.764 11.168 1.00 51.05 ? 348 LEU B CD2 1 ATOM 5906 N N . ASP B 2 317 ? 60.275 -9.650 9.183 1.00 37.92 ? 349 ASP B N 1 ATOM 5907 C CA . ASP B 2 317 ? 59.439 -10.838 9.230 1.00 37.41 ? 349 ASP B CA 1 ATOM 5908 C C . ASP B 2 317 ? 59.581 -11.684 7.975 1.00 35.73 ? 349 ASP B C 1 ATOM 5909 O O . ASP B 2 317 ? 60.266 -11.277 7.027 1.00 36.78 ? 349 ASP B O 1 ATOM 5910 C CB . ASP B 2 317 ? 57.976 -10.417 9.397 1.00 39.38 ? 349 ASP B CB 1 ATOM 5911 C CG . ASP B 2 317 ? 57.139 -11.459 10.129 1.00 40.59 ? 349 ASP B CG 1 ATOM 5912 O OD1 . ASP B 2 317 ? 57.208 -12.657 9.759 1.00 42.36 ? 349 ASP B OD1 1 ATOM 5913 O OD2 . ASP B 2 317 ? 56.395 -11.074 11.061 1.00 39.59 -1 349 ASP B OD2 1 ATOM 5914 N N . MET B 2 318 ? 58.946 -12.857 7.988 1.00 32.40 ? 350 MET B N 1 ATOM 5915 C CA . MET B 2 318 ? 58.743 -13.652 6.785 1.00 32.82 ? 350 MET B CA 1 ATOM 5916 C C . MET B 2 318 ? 57.327 -14.277 6.690 1.00 31.58 ? 350 MET B C 1 ATOM 5917 O O . MET B 2 318 ? 56.832 -14.874 7.665 1.00 29.35 ? 350 MET B O 1 ATOM 5918 C CB . MET B 2 318 ? 59.807 -14.749 6.727 1.00 34.50 ? 350 MET B CB 1 ATOM 5919 C CG . MET B 2 318 ? 59.782 -15.585 5.434 1.00 36.19 ? 350 MET B CG 1 ATOM 5920 S SD . MET B 2 318 ? 59.005 -17.221 5.539 1.00 36.44 ? 350 MET B SD 1 ATOM 5921 C CE . MET B 2 318 ? 60.283 -18.181 6.345 1.00 36.50 ? 350 MET B CE 1 ATOM 5922 N N . LEU B 2 319 ? 56.679 -14.167 5.521 1.00 29.53 ? 351 LEU B N 1 ATOM 5923 C CA . LEU B 2 319 ? 55.421 -14.906 5.319 1.00 28.50 ? 351 LEU B CA 1 ATOM 5924 C C . LEU B 2 319 ? 55.671 -16.046 4.357 1.00 27.69 ? 351 LEU B C 1 ATOM 5925 O O . LEU B 2 319 ? 56.363 -15.899 3.336 1.00 24.32 ? 351 LEU B O 1 ATOM 5926 C CB . LEU B 2 319 ? 54.268 -14.040 4.821 1.00 28.48 ? 351 LEU B CB 1 ATOM 5927 C CG . LEU B 2 319 ? 53.995 -12.721 5.548 1.00 29.24 ? 351 LEU B CG 1 ATOM 5928 C CD1 . LEU B 2 319 ? 55.129 -11.687 5.358 1.00 29.23 ? 351 LEU B CD1 1 ATOM 5929 C CD2 . LEU B 2 319 ? 52.646 -12.196 5.063 1.00 27.95 ? 351 LEU B CD2 1 ATOM 5930 N N . GLN B 2 320 ? 55.120 -17.199 4.721 1.00 28.24 ? 352 GLN B N 1 ATOM 5931 C CA . GLN B 2 320 ? 55.298 -18.392 3.937 1.00 28.53 ? 352 GLN B CA 1 ATOM 5932 C C . GLN B 2 320 ? 54.008 -18.740 3.305 1.00 28.51 ? 352 GLN B C 1 ATOM 5933 O O . GLN B 2 320 ? 53.023 -18.965 4.020 1.00 25.22 ? 352 GLN B O 1 ATOM 5934 C CB . GLN B 2 320 ? 55.741 -19.577 4.773 1.00 30.20 ? 352 GLN B CB 1 ATOM 5935 C CG . GLN B 2 320 ? 56.050 -20.814 3.916 1.00 32.40 ? 352 GLN B CG 1 ATOM 5936 C CD . GLN B 2 320 ? 57.388 -20.735 3.177 1.00 33.59 ? 352 GLN B CD 1 ATOM 5937 O OE1 . GLN B 2 320 ? 58.426 -20.473 3.800 1.00 35.60 ? 352 GLN B OE1 1 ATOM 5938 N NE2 . GLN B 2 320 ? 57.375 -20.971 1.851 1.00 33.58 ? 352 GLN B NE2 1 ATOM 5939 N N . TYR B 2 321 ? 54.046 -18.772 1.962 1.00 30.83 ? 353 TYR B N 1 ATOM 5940 C CA . TYR B 2 321 ? 52.943 -19.217 1.104 1.00 30.89 ? 353 TYR B CA 1 ATOM 5941 C C . TYR B 2 321 ? 53.204 -20.618 0.631 1.00 30.80 ? 353 TYR B C 1 ATOM 5942 O O . TYR B 2 321 ? 54.348 -21.047 0.558 1.00 30.09 ? 353 TYR B O 1 ATOM 5943 C CB . TYR B 2 321 ? 52.775 -18.304 -0.100 1.00 30.31 ? 353 TYR B CB 1 ATOM 5944 C CG . TYR B 2 321 ? 52.480 -16.904 0.320 1.00 31.37 ? 353 TYR B CG 1 ATOM 5945 C CD1 . TYR B 2 321 ? 51.204 -16.552 0.768 1.00 30.58 ? 353 TYR B CD1 1 ATOM 5946 C CD2 . TYR B 2 321 ? 53.490 -15.932 0.317 1.00 31.95 ? 353 TYR B CD2 1 ATOM 5947 C CE1 . TYR B 2 321 ? 50.932 -15.262 1.157 1.00 31.37 ? 353 TYR B CE1 1 ATOM 5948 C CE2 . TYR B 2 321 ? 53.232 -14.633 0.703 1.00 32.38 ? 353 TYR B CE2 1 ATOM 5949 C CZ . TYR B 2 321 ? 51.953 -14.302 1.121 1.00 33.26 ? 353 TYR B CZ 1 ATOM 5950 O OH . TYR B 2 321 ? 51.708 -13.009 1.521 1.00 34.48 ? 353 TYR B OH 1 ATOM 5951 N N . TYR B 2 322 ? 52.123 -21.321 0.303 1.00 32.32 ? 354 TYR B N 1 ATOM 5952 C CA . TYR B 2 322 ? 52.200 -22.724 -0.076 1.00 31.41 ? 354 TYR B CA 1 ATOM 5953 C C . TYR B 2 322 ? 50.971 -23.210 -0.878 1.00 30.97 ? 354 TYR B C 1 ATOM 5954 O O . TYR B 2 322 ? 49.914 -22.544 -0.896 1.00 27.42 ? 354 TYR B O 1 ATOM 5955 C CB . TYR B 2 322 ? 52.419 -23.555 1.181 1.00 30.90 ? 354 TYR B CB 1 ATOM 5956 C CG . TYR B 2 322 ? 51.165 -24.065 1.880 1.00 31.58 ? 354 TYR B CG 1 ATOM 5957 C CD1 . TYR B 2 322 ? 50.402 -23.251 2.719 1.00 31.09 ? 354 TYR B CD1 1 ATOM 5958 C CD2 . TYR B 2 322 ? 50.781 -25.399 1.739 1.00 32.12 ? 354 TYR B CD2 1 ATOM 5959 C CE1 . TYR B 2 322 ? 49.288 -23.761 3.372 1.00 31.94 ? 354 TYR B CE1 1 ATOM 5960 C CE2 . TYR B 2 322 ? 49.679 -25.914 2.386 1.00 32.20 ? 354 TYR B CE2 1 ATOM 5961 C CZ . TYR B 2 322 ? 48.933 -25.105 3.191 1.00 32.29 ? 354 TYR B CZ 1 ATOM 5962 O OH . TYR B 2 322 ? 47.847 -25.691 3.797 1.00 33.80 ? 354 TYR B OH 1 ATOM 5963 N N . LEU B 2 323 ? 51.141 -24.355 -1.555 1.00 31.75 ? 355 LEU B N 1 ATOM 5964 C CA . LEU B 2 323 ? 50.053 -25.018 -2.310 1.00 32.62 ? 355 LEU B CA 1 ATOM 5965 C C . LEU B 2 323 ? 49.773 -26.377 -1.667 1.00 33.52 ? 355 LEU B C 1 ATOM 5966 O O . LEU B 2 323 ? 50.642 -27.232 -1.687 1.00 34.34 ? 355 LEU B O 1 ATOM 5967 C CB . LEU B 2 323 ? 50.415 -25.175 -3.818 1.00 30.87 ? 355 LEU B CB 1 ATOM 5968 C CG . LEU B 2 323 ? 49.350 -25.513 -4.909 1.00 29.37 ? 355 LEU B CG 1 ATOM 5969 C CD1 . LEU B 2 323 ? 48.212 -24.527 -4.928 1.00 29.10 ? 355 LEU B CD1 1 ATOM 5970 C CD2 . LEU B 2 323 ? 49.920 -25.524 -6.325 1.00 28.25 ? 355 LEU B CD2 1 ATOM 5971 N N . ASN B 2 324 ? 48.595 -26.560 -1.057 1.00 34.90 ? 356 ASN B N 1 ATOM 5972 C CA . ASN B 2 324 ? 48.133 -27.913 -0.712 1.00 35.42 ? 356 ASN B CA 1 ATOM 5973 C C . ASN B 2 324 ? 47.833 -28.609 -2.058 1.00 35.61 ? 356 ASN B C 1 ATOM 5974 O O . ASN B 2 324 ? 46.704 -28.540 -2.599 1.00 33.36 ? 356 ASN B O 1 ATOM 5975 C CB . ASN B 2 324 ? 46.925 -27.934 0.262 1.00 36.39 ? 356 ASN B CB 1 ATOM 5976 C CG . ASN B 2 324 ? 46.473 -29.355 0.606 1.00 37.49 ? 356 ASN B CG 1 ATOM 5977 O OD1 . ASN B 2 324 ? 46.705 -30.281 -0.177 1.00 38.23 ? 356 ASN B OD1 1 ATOM 5978 N ND2 . ASN B 2 324 ? 45.832 -29.545 1.780 1.00 40.28 ? 356 ASN B ND2 1 ATOM 5979 N N . LEU B 2 325 ? 48.893 -29.246 -2.580 1.00 35.56 ? 357 LEU B N 1 ATOM 5980 C CA . LEU B 2 325 ? 48.921 -29.937 -3.877 1.00 33.30 ? 357 LEU B CA 1 ATOM 5981 C C . LEU B 2 325 ? 47.738 -30.903 -4.024 1.00 34.57 ? 357 LEU B C 1 ATOM 5982 O O . LEU B 2 325 ? 46.936 -30.759 -4.939 1.00 31.83 ? 357 LEU B O 1 ATOM 5983 C CB . LEU B 2 325 ? 50.274 -30.648 -4.044 1.00 31.04 ? 357 LEU B CB 1 ATOM 5984 C CG . LEU B 2 325 ? 50.541 -31.420 -5.332 1.00 29.69 ? 357 LEU B CG 1 ATOM 5985 C CD1 . LEU B 2 325 ? 50.331 -30.516 -6.537 1.00 29.79 ? 357 LEU B CD1 1 ATOM 5986 C CD2 . LEU B 2 325 ? 51.942 -32.000 -5.303 1.00 28.05 ? 357 LEU B CD2 1 ATOM 5987 N N . THR B 2 326 ? 47.608 -31.837 -3.081 1.00 38.23 ? 358 THR B N 1 ATOM 5988 C CA . THR B 2 326 ? 46.508 -32.811 -3.071 1.00 40.47 ? 358 THR B CA 1 ATOM 5989 C C . THR B 2 326 ? 45.128 -32.224 -3.249 1.00 42.13 ? 358 THR B C 1 ATOM 5990 O O . THR B 2 326 ? 44.325 -32.760 -4.006 1.00 41.61 ? 358 THR B O 1 ATOM 5991 C CB . THR B 2 326 ? 46.452 -33.539 -1.742 1.00 40.54 ? 358 THR B CB 1 ATOM 5992 O OG1 . THR B 2 326 ? 47.711 -34.170 -1.533 1.00 41.81 ? 358 THR B OG1 1 ATOM 5993 C CG2 . THR B 2 326 ? 45.322 -34.563 -1.754 1.00 40.50 ? 358 THR B CG2 1 ATOM 5994 N N . GLU B 2 327 ? 44.848 -31.173 -2.484 1.00 45.98 ? 359 GLU B N 1 ATOM 5995 C CA . GLU B 2 327 ? 43.614 -30.414 -2.607 1.00 48.13 ? 359 GLU B CA 1 ATOM 5996 C C . GLU B 2 327 ? 43.720 -29.744 -3.957 1.00 44.57 ? 359 GLU B C 1 ATOM 5997 O O . GLU B 2 327 ? 42.907 -30.013 -4.827 1.00 44.23 ? 359 GLU B O 1 ATOM 5998 C CB . GLU B 2 327 ? 43.483 -29.391 -1.466 1.00 54.53 ? 359 GLU B CB 1 ATOM 5999 C CG . GLU B 2 327 ? 42.287 -28.453 -1.536 1.00 59.75 ? 359 GLU B CG 1 ATOM 6000 C CD . GLU B 2 327 ? 42.678 -26.978 -1.348 1.00 67.71 ? 359 GLU B CD 1 ATOM 6001 O OE1 . GLU B 2 327 ? 42.385 -26.422 -0.255 1.00 68.62 ? 359 GLU B OE1 1 ATOM 6002 O OE2 . GLU B 2 327 ? 43.282 -26.378 -2.291 1.00 65.79 -1 359 GLU B OE2 1 ATOM 6003 N N . ALA B 2 328 ? 44.762 -28.937 -4.161 1.00 40.93 ? 360 ALA B N 1 ATOM 6004 C CA . ALA B 2 328 ? 44.936 -28.219 -5.429 1.00 40.59 ? 360 ALA B CA 1 ATOM 6005 C C . ALA B 2 328 ? 44.668 -29.087 -6.647 1.00 40.54 ? 360 ALA B C 1 ATOM 6006 O O . ALA B 2 328 ? 44.156 -28.611 -7.643 1.00 40.25 ? 360 ALA B O 1 ATOM 6007 C CB . ALA B 2 328 ? 46.320 -27.624 -5.531 1.00 40.38 ? 360 ALA B CB 1 ATOM 6008 N N . ASN B 2 329 ? 45.016 -30.361 -6.575 1.00 40.92 ? 361 ASN B N 1 ATOM 6009 C CA . ASN B 2 329 ? 44.635 -31.271 -7.626 1.00 41.10 ? 361 ASN B CA 1 ATOM 6010 C C . ASN B 2 329 ? 43.180 -31.645 -7.456 1.00 43.86 ? 361 ASN B C 1 ATOM 6011 O O . ASN B 2 329 ? 42.416 -31.401 -8.362 1.00 48.29 ? 361 ASN B O 1 ATOM 6012 C CB . ASN B 2 329 ? 45.549 -32.494 -7.698 1.00 41.33 ? 361 ASN B CB 1 ATOM 6013 C CG . ASN B 2 329 ? 46.865 -32.211 -8.430 1.00 42.41 ? 361 ASN B CG 1 ATOM 6014 O OD1 . ASN B 2 329 ? 46.986 -31.272 -9.225 1.00 41.24 ? 361 ASN B OD1 1 ATOM 6015 N ND2 . ASN B 2 329 ? 47.862 -33.039 -8.160 1.00 44.15 ? 361 ASN B ND2 1 ATOM 6016 N N . LEU B 2 330 ? 42.774 -32.167 -6.297 1.00 49.83 ? 362 LEU B N 1 ATOM 6017 C CA . LEU B 2 330 ? 41.357 -32.590 -6.060 1.00 52.23 ? 362 LEU B CA 1 ATOM 6018 C C . LEU B 2 330 ? 40.307 -31.629 -6.619 1.00 53.16 ? 362 LEU B C 1 ATOM 6019 O O . LEU B 2 330 ? 39.348 -32.076 -7.240 1.00 55.10 ? 362 LEU B O 1 ATOM 6020 C CB . LEU B 2 330 ? 41.046 -32.806 -4.562 1.00 52.42 ? 362 LEU B CB 1 ATOM 6021 C CG . LEU B 2 330 ? 41.281 -34.195 -3.954 1.00 52.74 ? 362 LEU B CG 1 ATOM 6022 C CD1 . LEU B 2 330 ? 40.880 -34.215 -2.481 1.00 51.45 ? 362 LEU B CD1 1 ATOM 6023 C CD2 . LEU B 2 330 ? 40.530 -35.258 -4.741 1.00 51.68 ? 362 LEU B CD2 1 ATOM 6024 N N . LYS B 2 331 ? 40.480 -30.328 -6.372 1.00 55.10 ? 363 LYS B N 1 ATOM 6025 C CA . LYS B 2 331 ? 39.561 -29.285 -6.872 1.00 56.58 ? 363 LYS B CA 1 ATOM 6026 C C . LYS B 2 331 ? 39.933 -28.880 -8.299 1.00 53.98 ? 363 LYS B C 1 ATOM 6027 O O . LYS B 2 331 ? 39.085 -28.455 -9.091 1.00 51.43 ? 363 LYS B O 1 ATOM 6028 C CB . LYS B 2 331 ? 39.583 -28.049 -5.946 1.00 59.41 ? 363 LYS B CB 1 ATOM 6029 C CG . LYS B 2 331 ? 38.907 -28.278 -4.598 1.00 62.38 ? 363 LYS B CG 1 ATOM 6030 C CD . LYS B 2 331 ? 39.479 -27.395 -3.494 1.00 67.53 ? 363 LYS B CD 1 ATOM 6031 C CE . LYS B 2 331 ? 38.946 -25.970 -3.525 1.00 71.86 ? 363 LYS B CE 1 ATOM 6032 N NZ . LYS B 2 331 ? 39.054 -25.318 -2.184 1.00 72.50 1 363 LYS B NZ 1 ATOM 6033 N N . GLY B 2 332 ? 41.213 -29.023 -8.619 1.00 50.88 ? 364 GLY B N 1 ATOM 6034 C CA . GLY B 2 332 ? 41.728 -28.585 -9.888 1.00 49.19 ? 364 GLY B CA 1 ATOM 6035 C C . GLY B 2 332 ? 41.714 -27.076 -9.894 1.00 49.88 ? 364 GLY B C 1 ATOM 6036 O O . GLY B 2 332 ? 41.173 -26.486 -10.806 1.00 51.74 ? 364 GLY B O 1 ATOM 6037 N N . GLU B 2 333 ? 42.279 -26.457 -8.854 1.00 52.10 ? 365 GLU B N 1 ATOM 6038 C CA . GLU B 2 333 ? 42.491 -25.000 -8.805 1.00 52.43 ? 365 GLU B CA 1 ATOM 6039 C C . GLU B 2 333 ? 43.796 -24.627 -8.044 1.00 48.74 ? 365 GLU B C 1 ATOM 6040 O O . GLU B 2 333 ? 44.208 -25.339 -7.128 1.00 46.02 ? 365 GLU B O 1 ATOM 6041 C CB . GLU B 2 333 ? 41.276 -24.307 -8.157 1.00 56.86 ? 365 GLU B CB 1 ATOM 6042 C CG . GLU B 2 333 ? 39.951 -24.328 -8.947 1.00 59.92 ? 365 GLU B CG 1 ATOM 6043 C CD . GLU B 2 333 ? 39.930 -23.470 -10.227 1.00 61.62 ? 365 GLU B CD 1 ATOM 6044 O OE1 . GLU B 2 333 ? 40.915 -22.745 -10.514 1.00 63.83 ? 365 GLU B OE1 1 ATOM 6045 O OE2 . GLU B 2 333 ? 38.910 -23.521 -10.961 1.00 62.28 -1 365 GLU B OE2 1 ATOM 6046 N N . SER B 2 334 ? 44.427 -23.513 -8.426 1.00 47.28 ? 366 SER B N 1 ATOM 6047 C CA . SER B 2 334 ? 45.637 -22.995 -7.755 1.00 48.53 ? 366 SER B CA 1 ATOM 6048 C C . SER B 2 334 ? 45.355 -22.286 -6.456 1.00 50.62 ? 366 SER B C 1 ATOM 6049 O O . SER B 2 334 ? 45.529 -21.063 -6.377 1.00 49.54 ? 366 SER B O 1 ATOM 6050 C CB . SER B 2 334 ? 46.336 -21.951 -8.612 1.00 51.04 ? 366 SER B CB 1 ATOM 6051 O OG . SER B 2 334 ? 46.711 -22.500 -9.836 1.00 59.17 ? 366 SER B OG 1 ATOM 6052 N N . ILE B 2 335 ? 44.980 -23.036 -5.429 1.00 52.59 ? 367 ILE B N 1 ATOM 6053 C CA . ILE B 2 335 ? 44.654 -22.440 -4.150 1.00 56.19 ? 367 ILE B CA 1 ATOM 6054 C C . ILE B 2 335 ? 45.950 -22.148 -3.383 1.00 52.30 ? 367 ILE B C 1 ATOM 6055 O O . ILE B 2 335 ? 46.342 -22.920 -2.485 1.00 56.62 ? 367 ILE B O 1 ATOM 6056 C CB . ILE B 2 335 ? 43.722 -23.360 -3.324 1.00 65.11 ? 367 ILE B CB 1 ATOM 6057 C CG1 . ILE B 2 335 ? 42.543 -23.875 -4.167 1.00 68.71 ? 367 ILE B CG1 1 ATOM 6058 C CG2 . ILE B 2 335 ? 43.179 -22.611 -2.114 1.00 68.74 ? 367 ILE B CG2 1 ATOM 6059 C CD1 . ILE B 2 335 ? 41.745 -22.783 -4.862 1.00 68.20 ? 367 ILE B CD1 1 ATOM 6060 N N . TRP B 2 336 ? 46.626 -21.054 -3.756 1.00 45.26 ? 368 TRP B N 1 ATOM 6061 C CA . TRP B 2 336 ? 47.833 -20.626 -3.053 1.00 43.83 ? 368 TRP B CA 1 ATOM 6062 C C . TRP B 2 336 ? 47.378 -20.044 -1.728 1.00 45.52 ? 368 TRP B C 1 ATOM 6063 O O . TRP B 2 336 ? 46.704 -19.031 -1.692 1.00 46.16 ? 368 TRP B O 1 ATOM 6064 C CB . TRP B 2 336 ? 48.707 -19.635 -3.870 1.00 42.99 ? 368 TRP B CB 1 ATOM 6065 C CG . TRP B 2 336 ? 49.685 -20.359 -4.736 1.00 44.28 ? 368 TRP B CG 1 ATOM 6066 C CD1 . TRP B 2 336 ? 49.508 -20.747 -6.047 1.00 47.18 ? 368 TRP B CD1 1 ATOM 6067 C CD2 . TRP B 2 336 ? 50.957 -20.877 -4.339 1.00 44.60 ? 368 TRP B CD2 1 ATOM 6068 N NE1 . TRP B 2 336 ? 50.601 -21.466 -6.487 1.00 46.13 ? 368 TRP B NE1 1 ATOM 6069 C CE2 . TRP B 2 336 ? 51.502 -21.564 -5.457 1.00 46.45 ? 368 TRP B CE2 1 ATOM 6070 C CE3 . TRP B 2 336 ? 51.691 -20.841 -3.144 1.00 42.46 ? 368 TRP B CE3 1 ATOM 6071 C CZ2 . TRP B 2 336 ? 52.752 -22.196 -5.411 1.00 44.81 ? 368 TRP B CZ2 1 ATOM 6072 C CZ3 . TRP B 2 336 ? 52.934 -21.476 -3.104 1.00 41.34 ? 368 TRP B CZ3 1 ATOM 6073 C CH2 . TRP B 2 336 ? 53.445 -22.144 -4.227 1.00 42.13 ? 368 TRP B CH2 1 ATOM 6074 N N . LYS B 2 337 ? 47.707 -20.727 -0.639 1.00 47.31 ? 369 LYS B N 1 ATOM 6075 C CA . LYS B 2 337 ? 47.355 -20.263 0.693 1.00 47.45 ? 369 LYS B CA 1 ATOM 6076 C C . LYS B 2 337 ? 48.584 -19.683 1.401 1.00 44.63 ? 369 LYS B C 1 ATOM 6077 O O . LYS B 2 337 ? 49.711 -19.763 0.903 1.00 41.54 ? 369 LYS B O 1 ATOM 6078 C CB . LYS B 2 337 ? 46.785 -21.414 1.539 1.00 51.17 ? 369 LYS B CB 1 ATOM 6079 C CG . LYS B 2 337 ? 45.601 -22.169 0.949 1.00 52.54 ? 369 LYS B CG 1 ATOM 6080 C CD . LYS B 2 337 ? 45.144 -23.253 1.923 1.00 56.14 ? 369 LYS B CD 1 ATOM 6081 C CE . LYS B 2 337 ? 44.327 -24.342 1.239 1.00 60.62 ? 369 LYS B CE 1 ATOM 6082 N NZ . LYS B 2 337 ? 44.436 -25.648 1.956 1.00 62.29 1 369 LYS B NZ 1 ATOM 6083 N N . LEU B 2 338 ? 48.318 -19.084 2.558 1.00 42.08 ? 370 LEU B N 1 ATOM 6084 C CA . LEU B 2 338 ? 49.327 -18.599 3.480 1.00 39.63 ? 370 LEU B CA 1 ATOM 6085 C C . LEU B 2 338 ? 49.568 -19.710 4.499 1.00 38.93 ? 370 LEU B C 1 ATOM 6086 O O . LEU B 2 338 ? 48.621 -20.220 5.093 1.00 38.76 ? 370 LEU B O 1 ATOM 6087 C CB . LEU B 2 338 ? 48.787 -17.363 4.184 1.00 39.43 ? 370 LEU B CB 1 ATOM 6088 C CG . LEU B 2 338 ? 49.550 -16.830 5.386 1.00 40.60 ? 370 LEU B CG 1 ATOM 6089 C CD1 . LEU B 2 338 ? 50.827 -16.104 4.961 1.00 42.68 ? 370 LEU B CD1 1 ATOM 6090 C CD2 . LEU B 2 338 ? 48.632 -15.928 6.190 1.00 39.81 ? 370 LEU B CD2 1 ATOM 6091 N N . GLU B 2 339 ? 50.827 -20.090 4.708 1.00 38.15 ? 371 GLU B N 1 ATOM 6092 C CA . GLU B 2 339 ? 51.156 -21.163 5.664 1.00 35.65 ? 371 GLU B CA 1 ATOM 6093 C C . GLU B 2 339 ? 51.422 -20.523 6.998 1.00 33.12 ? 371 GLU B C 1 ATOM 6094 O O . GLU B 2 339 ? 50.882 -20.971 7.993 1.00 34.90 ? 371 GLU B O 1 ATOM 6095 C CB . GLU B 2 339 ? 52.385 -21.986 5.231 1.00 35.34 ? 371 GLU B CB 1 ATOM 6096 C CG . GLU B 2 339 ? 52.554 -23.335 5.945 1.00 33.81 ? 371 GLU B CG 1 ATOM 6097 C CD . GLU B 2 339 ? 53.998 -23.884 5.918 1.00 33.66 ? 371 GLU B CD 1 ATOM 6098 O OE1 . GLU B 2 339 ? 54.950 -23.125 5.661 1.00 31.37 ? 371 GLU B OE1 1 ATOM 6099 O OE2 . GLU B 2 339 ? 54.208 -25.092 6.174 1.00 33.95 -1 371 GLU B OE2 1 ATOM 6100 N N . TYR B 2 340 ? 52.261 -19.492 7.023 1.00 31.19 ? 372 TYR B N 1 ATOM 6101 C CA . TYR B 2 340 ? 52.514 -18.789 8.256 1.00 31.75 ? 372 TYR B CA 1 ATOM 6102 C C . TYR B 2 340 ? 53.169 -17.451 8.062 1.00 33.49 ? 372 TYR B C 1 ATOM 6103 O O . TYR B 2 340 ? 53.799 -17.189 7.034 1.00 32.08 ? 372 TYR B O 1 ATOM 6104 C CB . TYR B 2 340 ? 53.373 -19.621 9.209 1.00 32.22 ? 372 TYR B CB 1 ATOM 6105 C CG . TYR B 2 340 ? 54.815 -19.773 8.795 1.00 34.23 ? 372 TYR B CG 1 ATOM 6106 C CD1 . TYR B 2 340 ? 55.758 -18.794 9.094 1.00 36.38 ? 372 TYR B CD1 1 ATOM 6107 C CD2 . TYR B 2 340 ? 55.246 -20.908 8.132 1.00 35.59 ? 372 TYR B CD2 1 ATOM 6108 C CE1 . TYR B 2 340 ? 57.089 -18.927 8.722 1.00 37.08 ? 372 TYR B CE1 1 ATOM 6109 C CE2 . TYR B 2 340 ? 56.575 -21.060 7.755 1.00 36.74 ? 372 TYR B CE2 1 ATOM 6110 C CZ . TYR B 2 340 ? 57.494 -20.070 8.043 1.00 36.92 ? 372 TYR B CZ 1 ATOM 6111 O OH . TYR B 2 340 ? 58.802 -20.242 7.653 1.00 34.18 ? 372 TYR B OH 1 ATOM 6112 N N . ILE B 2 341 ? 53.003 -16.622 9.101 1.00 37.28 ? 373 ILE B N 1 ATOM 6113 C CA . ILE B 2 341 ? 53.766 -15.372 9.309 1.00 38.69 ? 373 ILE B CA 1 ATOM 6114 C C . ILE B 2 341 ? 54.785 -15.582 10.449 1.00 35.25 ? 373 ILE B C 1 ATOM 6115 O O . ILE B 2 341 ? 54.376 -15.807 11.583 1.00 35.86 ? 373 ILE B O 1 ATOM 6116 C CB . ILE B 2 341 ? 52.832 -14.184 9.670 1.00 39.51 ? 373 ILE B CB 1 ATOM 6117 C CG1 . ILE B 2 341 ? 51.592 -14.181 8.759 1.00 40.71 ? 373 ILE B CG1 1 ATOM 6118 C CG2 . ILE B 2 341 ? 53.601 -12.851 9.601 1.00 38.35 ? 373 ILE B CG2 1 ATOM 6119 C CD1 . ILE B 2 341 ? 50.477 -13.261 9.223 1.00 42.25 ? 373 ILE B CD1 1 ATOM 6120 N N . LEU B 2 342 ? 56.084 -15.493 10.157 1.00 31.41 ? 374 LEU B N 1 ATOM 6121 C CA . LEU B 2 342 ? 57.082 -16.071 11.034 1.00 31.71 ? 374 LEU B CA 1 ATOM 6122 C C . LEU B 2 342 ? 56.967 -15.640 12.493 1.00 33.82 ? 374 LEU B C 1 ATOM 6123 O O . LEU B 2 342 ? 56.883 -16.499 13.400 1.00 33.32 ? 374 LEU B O 1 ATOM 6124 C CB . LEU B 2 342 ? 58.481 -15.804 10.526 1.00 32.61 ? 374 LEU B CB 1 ATOM 6125 C CG . LEU B 2 342 ? 59.510 -16.749 11.154 1.00 34.39 ? 374 LEU B CG 1 ATOM 6126 C CD1 . LEU B 2 342 ? 60.630 -17.005 10.174 1.00 35.15 ? 374 LEU B CD1 1 ATOM 6127 C CD2 . LEU B 2 342 ? 60.086 -16.209 12.461 1.00 35.72 ? 374 LEU B CD2 1 ATOM 6128 N N . THR B 2 343 ? 56.951 -14.329 12.732 1.00 35.60 ? 375 THR B N 1 ATOM 6129 C CA . THR B 2 343 ? 56.876 -13.800 14.117 1.00 36.32 ? 375 THR B CA 1 ATOM 6130 C C . THR B 2 343 ? 55.558 -14.160 14.810 1.00 37.59 ? 375 THR B C 1 ATOM 6131 O O . THR B 2 343 ? 55.533 -14.313 16.027 1.00 35.82 ? 375 THR B O 1 ATOM 6132 C CB . THR B 2 343 ? 57.047 -12.264 14.207 1.00 35.68 ? 375 THR B CB 1 ATOM 6133 O OG1 . THR B 2 343 ? 55.927 -11.614 13.597 1.00 36.13 ? 375 THR B OG1 1 ATOM 6134 C CG2 . THR B 2 343 ? 58.364 -11.790 13.562 1.00 34.84 ? 375 THR B CG2 1 ATOM 6135 N N . GLN B 2 344 ? 54.475 -14.283 14.034 1.00 40.62 ? 376 GLN B N 1 ATOM 6136 C CA . GLN B 2 344 ? 53.166 -14.713 14.553 1.00 43.48 ? 376 GLN B CA 1 ATOM 6137 C C . GLN B 2 344 ? 53.166 -16.099 15.182 1.00 40.60 ? 376 GLN B C 1 ATOM 6138 O O . GLN B 2 344 ? 52.844 -16.233 16.353 1.00 39.29 ? 376 GLN B O 1 ATOM 6139 C CB . GLN B 2 344 ? 52.110 -14.717 13.443 1.00 50.82 ? 376 GLN B CB 1 ATOM 6140 C CG . GLN B 2 344 ? 51.625 -13.345 13.016 1.00 56.62 ? 376 GLN B CG 1 ATOM 6141 C CD . GLN B 2 344 ? 50.822 -12.675 14.099 1.00 64.24 ? 376 GLN B CD 1 ATOM 6142 O OE1 . GLN B 2 344 ? 50.515 -13.286 15.127 1.00 70.40 ? 376 GLN B OE1 1 ATOM 6143 N NE2 . GLN B 2 344 ? 50.478 -11.411 13.883 1.00 70.58 ? 376 GLN B NE2 1 ATOM 6144 N N . THR B 2 345 ? 53.508 -17.125 14.404 1.00 39.47 ? 377 THR B N 1 ATOM 6145 C CA . THR B 2 345 ? 53.410 -18.521 14.872 1.00 38.61 ? 377 THR B CA 1 ATOM 6146 C C . THR B 2 345 ? 54.470 -18.919 15.880 1.00 38.78 ? 377 THR B C 1 ATOM 6147 O O . THR B 2 345 ? 54.338 -19.958 16.539 1.00 37.27 ? 377 THR B O 1 ATOM 6148 C CB . THR B 2 345 ? 53.523 -19.535 13.727 1.00 37.07 ? 377 THR B CB 1 ATOM 6149 O OG1 . THR B 2 345 ? 54.645 -19.186 12.917 1.00 36.30 ? 377 THR B OG1 1 ATOM 6150 C CG2 . THR B 2 345 ? 52.259 -19.540 12.897 1.00 38.61 ? 377 THR B CG2 1 ATOM 6151 N N . TYR B 2 346 ? 55.536 -18.138 15.973 1.00 39.43 ? 378 TYR B N 1 ATOM 6152 C CA . TYR B 2 346 ? 56.552 -18.408 16.975 1.00 41.64 ? 378 TYR B CA 1 ATOM 6153 C C . TYR B 2 346 ? 56.493 -17.443 18.149 1.00 43.18 ? 378 TYR B C 1 ATOM 6154 O O . TYR B 2 346 ? 57.029 -17.726 19.227 1.00 43.93 ? 378 TYR B O 1 ATOM 6155 C CB . TYR B 2 346 ? 57.930 -18.413 16.325 1.00 41.60 ? 378 TYR B CB 1 ATOM 6156 C CG . TYR B 2 346 ? 58.095 -19.560 15.356 1.00 41.24 ? 378 TYR B CG 1 ATOM 6157 C CD1 . TYR B 2 346 ? 57.931 -20.884 15.776 1.00 40.55 ? 378 TYR B CD1 1 ATOM 6158 C CD2 . TYR B 2 346 ? 58.412 -19.326 14.018 1.00 42.09 ? 378 TYR B CD2 1 ATOM 6159 C CE1 . TYR B 2 346 ? 58.078 -21.943 14.886 1.00 42.16 ? 378 TYR B CE1 1 ATOM 6160 C CE2 . TYR B 2 346 ? 58.570 -20.376 13.116 1.00 42.53 ? 378 TYR B CE2 1 ATOM 6161 C CZ . TYR B 2 346 ? 58.399 -21.683 13.546 1.00 42.02 ? 378 TYR B CZ 1 ATOM 6162 O OH . TYR B 2 346 ? 58.559 -22.714 12.647 1.00 37.12 ? 378 TYR B OH 1 ATOM 6163 N N . ASP B 2 347 ? 55.822 -16.318 17.939 1.00 44.90 ? 379 ASP B N 1 ATOM 6164 C CA . ASP B 2 347 ? 55.727 -15.266 18.941 1.00 47.78 ? 379 ASP B CA 1 ATOM 6165 C C . ASP B 2 347 ? 57.108 -14.739 19.383 1.00 47.23 ? 379 ASP B C 1 ATOM 6166 O O . ASP B 2 347 ? 57.467 -14.781 20.555 1.00 48.67 ? 379 ASP B O 1 ATOM 6167 C CB . ASP B 2 347 ? 54.875 -15.722 20.120 1.00 48.54 ? 379 ASP B CB 1 ATOM 6168 C CG . ASP B 2 347 ? 54.010 -14.615 20.639 1.00 51.77 ? 379 ASP B CG 1 ATOM 6169 O OD1 . ASP B 2 347 ? 54.565 -13.684 21.253 1.00 53.67 ? 379 ASP B OD1 1 ATOM 6170 O OD2 . ASP B 2 347 ? 52.784 -14.657 20.402 1.00 56.79 -1 379 ASP B OD2 1 ATOM 6171 N N . ILE B 2 348 ? 57.857 -14.241 18.402 1.00 45.64 ? 380 ILE B N 1 ATOM 6172 C CA . ILE B 2 348 ? 59.148 -13.616 18.613 1.00 44.53 ? 380 ILE B CA 1 ATOM 6173 C C . ILE B 2 348 ? 59.082 -12.234 17.962 1.00 46.36 ? 380 ILE B C 1 ATOM 6174 O O . ILE B 2 348 ? 58.186 -11.987 17.156 1.00 43.83 ? 380 ILE B O 1 ATOM 6175 C CB . ILE B 2 348 ? 60.283 -14.492 18.051 1.00 44.11 ? 380 ILE B CB 1 ATOM 6176 C CG1 . ILE B 2 348 ? 60.084 -14.767 16.557 1.00 45.79 ? 380 ILE B CG1 1 ATOM 6177 C CG2 . ILE B 2 348 ? 60.325 -15.815 18.798 1.00 43.23 ? 380 ILE B CG2 1 ATOM 6178 C CD1 . ILE B 2 348 ? 61.283 -15.400 15.878 1.00 45.57 ? 380 ILE B CD1 1 ATOM 6179 N N . GLU B 2 349 ? 60.003 -11.341 18.331 1.00 51.37 ? 381 GLU B N 1 ATOM 6180 C CA . GLU B 2 349 ? 59.910 -9.902 17.981 1.00 54.60 ? 381 GLU B CA 1 ATOM 6181 C C . GLU B 2 349 ? 60.095 -9.605 16.492 1.00 54.10 ? 381 GLU B C 1 ATOM 6182 O O . GLU B 2 349 ? 59.279 -8.914 15.874 1.00 51.55 ? 381 GLU B O 1 ATOM 6183 C CB . GLU B 2 349 ? 60.947 -9.075 18.766 1.00 59.11 ? 381 GLU B CB 1 ATOM 6184 C CG . GLU B 2 349 ? 60.687 -8.935 20.259 1.00 66.29 ? 381 GLU B CG 1 ATOM 6185 C CD . GLU B 2 349 ? 59.237 -8.591 20.575 1.00 74.26 ? 381 GLU B CD 1 ATOM 6186 O OE1 . GLU B 2 349 ? 58.732 -7.583 20.032 1.00 81.32 ? 381 GLU B OE1 1 ATOM 6187 O OE2 . GLU B 2 349 ? 58.596 -9.335 21.354 1.00 77.22 -1 381 GLU B OE2 1 ATOM 6188 N N . ASP B 2 350 ? 61.190 -10.125 15.940 1.00 53.13 ? 382 ASP B N 1 ATOM 6189 C CA . ASP B 2 350 ? 61.613 -9.850 14.570 1.00 47.99 ? 382 ASP B CA 1 ATOM 6190 C C . ASP B 2 350 ? 62.418 -11.051 14.040 1.00 45.04 ? 382 ASP B C 1 ATOM 6191 O O . ASP B 2 350 ? 62.262 -12.168 14.538 1.00 44.25 ? 382 ASP B O 1 ATOM 6192 C CB . ASP B 2 350 ? 62.430 -8.547 14.548 1.00 48.71 ? 382 ASP B CB 1 ATOM 6193 C CG . ASP B 2 350 ? 63.624 -8.567 15.514 1.00 48.25 ? 382 ASP B CG 1 ATOM 6194 O OD1 . ASP B 2 350 ? 64.061 -9.656 15.934 1.00 48.84 ? 382 ASP B OD1 1 ATOM 6195 O OD2 . ASP B 2 350 ? 64.138 -7.483 15.850 1.00 48.52 -1 382 ASP B OD2 1 ATOM 6196 N N . LEU B 2 351 ? 63.265 -10.827 13.038 1.00 41.93 ? 383 LEU B N 1 ATOM 6197 C CA . LEU B 2 351 ? 64.110 -11.864 12.503 1.00 39.95 ? 383 LEU B CA 1 ATOM 6198 C C . LEU B 2 351 ? 65.550 -11.507 12.766 1.00 42.41 ? 383 LEU B C 1 ATOM 6199 O O . LEU B 2 351 ? 66.410 -11.749 11.936 1.00 48.57 ? 383 LEU B O 1 ATOM 6200 C CB . LEU B 2 351 ? 63.848 -12.035 11.001 1.00 39.77 ? 383 LEU B CB 1 ATOM 6201 C CG . LEU B 2 351 ? 62.834 -13.112 10.617 1.00 38.55 ? 383 LEU B CG 1 ATOM 6202 C CD1 . LEU B 2 351 ? 61.570 -12.979 11.440 1.00 39.30 ? 383 LEU B CD1 1 ATOM 6203 C CD2 . LEU B 2 351 ? 62.508 -13.036 9.148 1.00 38.21 ? 383 LEU B CD2 1 ATOM 6204 N N . GLN B 2 352 ? 65.836 -10.941 13.930 1.00 45.24 ? 384 GLN B N 1 ATOM 6205 C CA . GLN B 2 352 ? 67.224 -10.694 14.320 1.00 47.03 ? 384 GLN B CA 1 ATOM 6206 C C . GLN B 2 352 ? 67.896 -12.013 14.669 1.00 44.54 ? 384 GLN B C 1 ATOM 6207 O O . GLN B 2 352 ? 67.219 -13.019 14.815 1.00 43.45 ? 384 GLN B O 1 ATOM 6208 C CB . GLN B 2 352 ? 67.272 -9.748 15.511 1.00 51.73 ? 384 GLN B CB 1 ATOM 6209 C CG . GLN B 2 352 ? 67.004 -8.307 15.115 1.00 53.94 ? 384 GLN B CG 1 ATOM 6210 C CD . GLN B 2 352 ? 68.255 -7.642 14.605 1.00 54.29 ? 384 GLN B CD 1 ATOM 6211 O OE1 . GLN B 2 352 ? 68.376 -7.364 13.419 1.00 53.53 ? 384 GLN B OE1 1 ATOM 6212 N NE2 . GLN B 2 352 ? 69.217 -7.424 15.502 1.00 55.98 ? 384 GLN B NE2 1 ATOM 6213 N N . PRO B 2 353 ? 69.230 -12.028 14.771 1.00 45.11 ? 385 PRO B N 1 ATOM 6214 C CA . PRO B 2 353 ? 69.895 -13.270 15.174 1.00 46.68 ? 385 PRO B CA 1 ATOM 6215 C C . PRO B 2 353 ? 69.568 -13.693 16.608 1.00 48.99 ? 385 PRO B C 1 ATOM 6216 O O . PRO B 2 353 ? 69.456 -14.908 16.879 1.00 49.63 ? 385 PRO B O 1 ATOM 6217 C CB . PRO B 2 353 ? 71.389 -12.944 15.039 1.00 45.93 ? 385 PRO B CB 1 ATOM 6218 C CG . PRO B 2 353 ? 71.446 -11.816 14.068 1.00 46.61 ? 385 PRO B CG 1 ATOM 6219 C CD . PRO B 2 353 ? 70.189 -11.020 14.295 1.00 47.04 ? 385 PRO B CD 1 ATOM 6220 N N . GLU B 2 354 ? 69.411 -12.712 17.505 1.00 48.44 ? 386 GLU B N 1 ATOM 6221 C CA . GLU B 2 354 ? 69.095 -13.003 18.907 1.00 50.46 ? 386 GLU B CA 1 ATOM 6222 C C . GLU B 2 354 ? 67.659 -13.569 18.954 1.00 46.62 ? 386 GLU B C 1 ATOM 6223 O O . GLU B 2 354 ? 67.427 -14.632 19.543 1.00 46.18 ? 386 GLU B O 1 ATOM 6224 C CB . GLU B 2 354 ? 69.280 -11.778 19.844 1.00 57.13 ? 386 GLU B CB 1 ATOM 6225 C CG . GLU B 2 354 ? 70.580 -10.960 19.680 1.00 64.00 ? 386 GLU B CG 1 ATOM 6226 C CD . GLU B 2 354 ? 70.447 -9.769 18.702 1.00 73.40 ? 386 GLU B CD 1 ATOM 6227 O OE1 . GLU B 2 354 ? 69.519 -8.931 18.877 1.00 79.77 ? 386 GLU B OE1 1 ATOM 6228 O OE2 . GLU B 2 354 ? 71.268 -9.663 17.750 1.00 70.35 -1 386 GLU B OE2 1 ATOM 6229 N N . SER B 2 355 ? 66.717 -12.901 18.284 1.00 42.56 ? 387 SER B N 1 ATOM 6230 C CA . SER B 2 355 ? 65.313 -13.366 18.227 1.00 40.86 ? 387 SER B CA 1 ATOM 6231 C C . SER B 2 355 ? 65.122 -14.833 17.833 1.00 40.27 ? 387 SER B C 1 ATOM 6232 O O . SER B 2 355 ? 64.282 -15.524 18.403 1.00 44.04 ? 387 SER B O 1 ATOM 6233 C CB . SER B 2 355 ? 64.495 -12.506 17.265 1.00 39.34 ? 387 SER B CB 1 ATOM 6234 O OG . SER B 2 355 ? 64.181 -11.269 17.858 1.00 38.57 ? 387 SER B OG 1 ATOM 6235 N N . LEU B 2 356 ? 65.890 -15.286 16.849 1.00 40.42 ? 388 LEU B N 1 ATOM 6236 C CA . LEU B 2 356 ? 65.803 -16.656 16.323 1.00 40.07 ? 388 LEU B CA 1 ATOM 6237 C C . LEU B 2 356 ? 66.654 -17.653 17.097 1.00 40.42 ? 388 LEU B C 1 ATOM 6238 O O . LEU B 2 356 ? 66.330 -18.850 17.105 1.00 37.92 ? 388 LEU B O 1 ATOM 6239 C CB . LEU B 2 356 ? 66.252 -16.705 14.859 1.00 38.54 ? 388 LEU B CB 1 ATOM 6240 C CG . LEU B 2 356 ? 65.476 -15.892 13.844 1.00 36.84 ? 388 LEU B CG 1 ATOM 6241 C CD1 . LEU B 2 356 ? 66.081 -16.133 12.473 1.00 37.03 ? 388 LEU B CD1 1 ATOM 6242 C CD2 . LEU B 2 356 ? 64.009 -16.282 13.880 1.00 36.92 ? 388 LEU B CD2 1 ATOM 6243 N N . TYR B 2 357 ? 67.762 -17.182 17.687 1.00 40.87 ? 389 TYR B N 1 ATOM 6244 C CA . TYR B 2 357 ? 68.543 -18.030 18.582 1.00 41.56 ? 389 TYR B CA 1 ATOM 6245 C C . TYR B 2 357 ? 67.648 -18.442 19.723 1.00 40.28 ? 389 TYR B C 1 ATOM 6246 O O . TYR B 2 357 ? 67.552 -19.635 20.060 1.00 38.94 ? 389 TYR B O 1 ATOM 6247 C CB . TYR B 2 357 ? 69.759 -17.316 19.155 1.00 43.08 ? 389 TYR B CB 1 ATOM 6248 C CG . TYR B 2 357 ? 70.724 -18.295 19.794 1.00 46.00 ? 389 TYR B CG 1 ATOM 6249 C CD1 . TYR B 2 357 ? 71.349 -19.267 19.007 1.00 47.45 ? 389 TYR B CD1 1 ATOM 6250 C CD2 . TYR B 2 357 ? 71.004 -18.269 21.170 1.00 45.84 ? 389 TYR B CD2 1 ATOM 6251 C CE1 . TYR B 2 357 ? 72.222 -20.181 19.555 1.00 49.74 ? 389 TYR B CE1 1 ATOM 6252 C CE2 . TYR B 2 357 ? 71.889 -19.182 21.726 1.00 47.60 ? 389 TYR B CE2 1 ATOM 6253 C CZ . TYR B 2 357 ? 72.493 -20.136 20.900 1.00 49.96 ? 389 TYR B CZ 1 ATOM 6254 O OH . TYR B 2 357 ? 73.372 -21.079 21.364 1.00 51.73 ? 389 TYR B OH 1 ATOM 6255 N N . GLY B 2 358 ? 66.985 -17.431 20.288 1.00 37.69 ? 390 GLY B N 1 ATOM 6256 C CA . GLY B 2 358 ? 66.013 -17.605 21.364 1.00 38.03 ? 390 GLY B CA 1 ATOM 6257 C C . GLY B 2 358 ? 64.899 -18.597 21.088 1.00 37.09 ? 390 GLY B C 1 ATOM 6258 O O . GLY B 2 358 ? 64.475 -19.339 21.996 1.00 37.16 ? 390 GLY B O 1 ATOM 6259 N N . LEU B 2 359 ? 64.425 -18.596 19.841 1.00 34.72 ? 391 LEU B N 1 ATOM 6260 C CA . LEU B 2 359 ? 63.477 -19.596 19.370 1.00 33.13 ? 391 LEU B CA 1 ATOM 6261 C C . LEU B 2 359 ? 64.093 -21.030 19.301 1.00 33.80 ? 391 LEU B C 1 ATOM 6262 O O . LEU B 2 359 ? 63.479 -21.984 19.777 1.00 32.76 ? 391 LEU B O 1 ATOM 6263 C CB . LEU B 2 359 ? 62.891 -19.149 18.033 1.00 31.16 ? 391 LEU B CB 1 ATOM 6264 C CG . LEU B 2 359 ? 61.756 -19.985 17.444 1.00 31.45 ? 391 LEU B CG 1 ATOM 6265 C CD1 . LEU B 2 359 ? 60.495 -19.981 18.298 1.00 30.80 ? 391 LEU B CD1 1 ATOM 6266 C CD2 . LEU B 2 359 ? 61.440 -19.476 16.047 1.00 32.85 ? 391 LEU B CD2 1 ATOM 6267 N N . ALA B 2 360 ? 65.307 -21.175 18.753 1.00 35.63 ? 392 ALA B N 1 ATOM 6268 C CA . ALA B 2 360 ? 65.999 -22.499 18.648 1.00 35.75 ? 392 ALA B CA 1 ATOM 6269 C C . ALA B 2 360 ? 66.140 -23.232 20.002 1.00 36.33 ? 392 ALA B C 1 ATOM 6270 O O . ALA B 2 360 ? 66.115 -24.479 20.078 1.00 32.44 ? 392 ALA B O 1 ATOM 6271 C CB . ALA B 2 360 ? 67.379 -22.315 18.036 1.00 35.25 ? 392 ALA B CB 1 ATOM 6272 N N . LYS B 2 361 ? 66.304 -22.421 21.052 1.00 35.27 ? 393 LYS B N 1 ATOM 6273 C CA . LYS B 2 361 ? 66.397 -22.881 22.421 1.00 31.90 ? 393 LYS B CA 1 ATOM 6274 C C . LYS B 2 361 ? 65.043 -23.410 22.864 1.00 30.88 ? 393 LYS B C 1 ATOM 6275 O O . LYS B 2 361 ? 64.963 -24.457 23.487 1.00 29.65 ? 393 LYS B O 1 ATOM 6276 C CB . LYS B 2 361 ? 66.908 -21.740 23.287 1.00 31.37 ? 393 LYS B CB 1 ATOM 6277 C CG . LYS B 2 361 ? 68.296 -21.296 22.838 1.00 32.88 ? 393 LYS B CG 1 ATOM 6278 C CD . LYS B 2 361 ? 69.423 -21.844 23.713 1.00 35.71 ? 393 LYS B CD 1 ATOM 6279 C CE . LYS B 2 361 ? 70.151 -20.749 24.497 1.00 37.87 ? 393 LYS B CE 1 ATOM 6280 N NZ . LYS B 2 361 ? 69.315 -19.551 24.855 1.00 39.09 1 393 LYS B NZ 1 ATOM 6281 N N . GLN B 2 362 ? 63.970 -22.730 22.491 1.00 31.56 ? 394 GLN B N 1 ATOM 6282 C CA . GLN B 2 362 ? 62.631 -23.211 22.826 1.00 33.81 ? 394 GLN B CA 1 ATOM 6283 C C . GLN B 2 362 ? 62.325 -24.547 22.179 1.00 33.51 ? 394 GLN B C 1 ATOM 6284 O O . GLN B 2 362 ? 61.547 -25.330 22.687 1.00 34.68 ? 394 GLN B O 1 ATOM 6285 C CB . GLN B 2 362 ? 61.553 -22.217 22.402 1.00 37.37 ? 394 GLN B CB 1 ATOM 6286 C CG . GLN B 2 362 ? 61.541 -20.871 23.130 1.00 39.59 ? 394 GLN B CG 1 ATOM 6287 C CD . GLN B 2 362 ? 60.425 -19.969 22.610 1.00 42.56 ? 394 GLN B CD 1 ATOM 6288 O OE1 . GLN B 2 362 ? 60.675 -18.888 22.060 1.00 41.80 ? 394 GLN B OE1 1 ATOM 6289 N NE2 . GLN B 2 362 ? 59.175 -20.431 22.756 1.00 46.23 ? 394 GLN B NE2 1 ATOM 6290 N N . PHE B 2 363 ? 62.915 -24.811 21.035 1.00 34.97 ? 395 PHE B N 1 ATOM 6291 C CA . PHE B 2 363 ? 62.735 -26.117 20.428 1.00 37.02 ? 395 PHE B CA 1 ATOM 6292 C C . PHE B 2 363 ? 63.364 -27.212 21.281 1.00 38.51 ? 395 PHE B C 1 ATOM 6293 O O . PHE B 2 363 ? 62.848 -28.316 21.335 1.00 37.03 ? 395 PHE B O 1 ATOM 6294 C CB . PHE B 2 363 ? 63.350 -26.170 19.027 1.00 38.73 ? 395 PHE B CB 1 ATOM 6295 C CG . PHE B 2 363 ? 62.714 -25.241 18.021 1.00 40.07 ? 395 PHE B CG 1 ATOM 6296 C CD1 . PHE B 2 363 ? 61.511 -24.570 18.273 1.00 38.51 ? 395 PHE B CD1 1 ATOM 6297 C CD2 . PHE B 2 363 ? 63.326 -25.069 16.786 1.00 43.84 ? 395 PHE B CD2 1 ATOM 6298 C CE1 . PHE B 2 363 ? 60.963 -23.726 17.331 1.00 39.22 ? 395 PHE B CE1 1 ATOM 6299 C CE2 . PHE B 2 363 ? 62.785 -24.220 15.834 1.00 45.82 ? 395 PHE B CE2 1 ATOM 6300 C CZ . PHE B 2 363 ? 61.599 -23.546 16.113 1.00 44.27 ? 395 PHE B CZ 1 ATOM 6301 N N . THR B 2 364 ? 64.477 -26.892 21.945 1.00 41.28 ? 396 THR B N 1 ATOM 6302 C CA . THR B 2 364 ? 65.228 -27.839 22.800 1.00 40.24 ? 396 THR B CA 1 ATOM 6303 C C . THR B 2 364 ? 64.453 -28.327 24.067 1.00 45.01 ? 396 THR B C 1 ATOM 6304 O O . THR B 2 364 ? 64.828 -29.331 24.731 1.00 45.23 ? 396 THR B O 1 ATOM 6305 C CB . THR B 2 364 ? 66.551 -27.195 23.247 1.00 37.95 ? 396 THR B CB 1 ATOM 6306 O OG1 . THR B 2 364 ? 66.297 -26.177 24.222 1.00 34.83 ? 396 THR B OG1 1 ATOM 6307 C CG2 . THR B 2 364 ? 67.254 -26.576 22.067 1.00 38.60 ? 396 THR B CG2 1 ATOM 6308 N N . ILE B 2 365 ? 63.386 -27.595 24.404 1.00 45.72 ? 397 ILE B N 1 ATOM 6309 C CA . ILE B 2 365 ? 62.461 -27.973 25.470 1.00 43.91 ? 397 ILE B CA 1 ATOM 6310 C C . ILE B 2 365 ? 61.950 -29.421 25.220 1.00 47.36 ? 397 ILE B C 1 ATOM 6311 O O . ILE B 2 365 ? 61.515 -29.738 24.111 1.00 49.76 ? 397 ILE B O 1 ATOM 6312 C CB . ILE B 2 365 ? 61.266 -26.982 25.501 1.00 40.43 ? 397 ILE B CB 1 ATOM 6313 C CG1 . ILE B 2 365 ? 61.698 -25.564 25.874 1.00 38.62 ? 397 ILE B CG1 1 ATOM 6314 C CG2 . ILE B 2 365 ? 60.186 -27.446 26.459 1.00 40.35 ? 397 ILE B CG2 1 ATOM 6315 C CD1 . ILE B 2 365 ? 60.631 -24.528 25.544 1.00 39.60 ? 397 ILE B CD1 1 ATOM 6316 N N . LEU B 2 366 ? 61.997 -30.301 26.223 1.00 47.65 ? 398 LEU B N 1 ATOM 6317 C CA . LEU B 2 366 ? 61.370 -31.630 26.076 1.00 45.39 ? 398 LEU B CA 1 ATOM 6318 C C . LEU B 2 366 ? 59.936 -31.426 25.535 1.00 43.35 ? 398 LEU B C 1 ATOM 6319 O O . LEU B 2 366 ? 59.156 -30.621 26.054 1.00 38.47 ? 398 LEU B O 1 ATOM 6320 C CB . LEU B 2 366 ? 61.353 -32.410 27.414 1.00 48.29 ? 398 LEU B CB 1 ATOM 6321 C CG . LEU B 2 366 ? 62.597 -33.030 28.116 1.00 47.54 ? 398 LEU B CG 1 ATOM 6322 C CD1 . LEU B 2 366 ? 63.952 -32.405 27.748 1.00 46.79 ? 398 LEU B CD1 1 ATOM 6323 C CD2 . LEU B 2 366 ? 62.376 -33.008 29.638 1.00 45.89 ? 398 LEU B CD2 1 ATOM 6324 N N . ASP B 2 367 ? 59.610 -32.131 24.462 1.00 46.14 ? 399 ASP B N 1 ATOM 6325 C CA . ASP B 2 367 ? 58.273 -32.063 23.840 1.00 47.41 ? 399 ASP B CA 1 ATOM 6326 C C . ASP B 2 367 ? 57.831 -30.647 23.413 1.00 42.72 ? 399 ASP B C 1 ATOM 6327 O O . ASP B 2 367 ? 56.637 -30.354 23.429 1.00 40.02 ? 399 ASP B O 1 ATOM 6328 C CB . ASP B 2 367 ? 57.203 -32.695 24.775 1.00 51.05 ? 399 ASP B CB 1 ATOM 6329 C CG . ASP B 2 367 ? 56.946 -34.191 24.497 1.00 53.10 ? 399 ASP B CG 1 ATOM 6330 O OD1 . ASP B 2 367 ? 57.010 -34.629 23.318 1.00 50.68 ? 399 ASP B OD1 1 ATOM 6331 O OD2 . ASP B 2 367 ? 56.627 -34.913 25.481 1.00 54.80 -1 399 ASP B OD2 1 ATOM 6332 N N . SER B 2 368 ? 58.779 -29.797 23.007 1.00 40.84 ? 400 SER B N 1 ATOM 6333 C CA . SER B 2 368 ? 58.474 -28.417 22.515 1.00 41.60 ? 400 SER B CA 1 ATOM 6334 C C . SER B 2 368 ? 57.408 -28.351 21.416 1.00 43.85 ? 400 SER B C 1 ATOM 6335 O O . SER B 2 368 ? 57.622 -28.834 20.308 1.00 44.52 ? 400 SER B O 1 ATOM 6336 C CB . SER B 2 368 ? 59.728 -27.702 21.974 1.00 37.93 ? 400 SER B CB 1 ATOM 6337 O OG . SER B 2 368 ? 59.426 -26.378 21.579 1.00 32.96 ? 400 SER B OG 1 ATOM 6338 N N . LYS B 2 369 ? 56.280 -27.722 21.744 1.00 46.23 ? 401 LYS B N 1 ATOM 6339 C CA . LYS B 2 369 ? 55.191 -27.456 20.804 1.00 45.95 ? 401 LYS B CA 1 ATOM 6340 C C . LYS B 2 369 ? 55.688 -26.519 19.702 1.00 42.66 ? 401 LYS B C 1 ATOM 6341 O O . LYS B 2 369 ? 55.124 -26.481 18.610 1.00 42.41 ? 401 LYS B O 1 ATOM 6342 C CB . LYS B 2 369 ? 53.987 -26.813 21.537 1.00 49.56 ? 401 LYS B CB 1 ATOM 6343 C CG . LYS B 2 369 ? 52.975 -27.771 22.172 1.00 54.62 ? 401 LYS B CG 1 ATOM 6344 C CD . LYS B 2 369 ? 53.572 -28.740 23.201 1.00 60.67 ? 401 LYS B CD 1 ATOM 6345 C CE . LYS B 2 369 ? 53.059 -30.177 23.005 1.00 65.07 ? 401 LYS B CE 1 ATOM 6346 N NZ . LYS B 2 369 ? 54.003 -31.224 23.511 1.00 64.68 1 401 LYS B NZ 1 ATOM 6347 N N . GLN B 2 370 ? 56.739 -25.755 20.002 1.00 40.94 ? 402 GLN B N 1 ATOM 6348 C CA . GLN B 2 370 ? 57.355 -24.854 19.023 1.00 41.36 ? 402 GLN B CA 1 ATOM 6349 C C . GLN B 2 370 ? 58.065 -25.625 17.898 1.00 41.74 ? 402 GLN B C 1 ATOM 6350 O O . GLN B 2 370 ? 57.791 -25.372 16.720 1.00 45.46 ? 402 GLN B O 1 ATOM 6351 C CB . GLN B 2 370 ? 58.344 -23.892 19.707 1.00 41.50 ? 402 GLN B CB 1 ATOM 6352 C CG . GLN B 2 370 ? 57.721 -22.835 20.616 1.00 40.61 ? 402 GLN B CG 1 ATOM 6353 C CD . GLN B 2 370 ? 56.980 -21.751 19.834 1.00 40.02 ? 402 GLN B CD 1 ATOM 6354 O OE1 . GLN B 2 370 ? 55.894 -21.989 19.266 1.00 39.54 ? 402 GLN B OE1 1 ATOM 6355 N NE2 . GLN B 2 370 ? 57.560 -20.551 19.800 1.00 38.67 ? 402 GLN B NE2 1 ATOM 6356 N N . PHE B 2 371 ? 58.955 -26.560 18.268 1.00 37.87 ? 403 PHE B N 1 ATOM 6357 C CA . PHE B 2 371 ? 59.652 -27.436 17.317 1.00 33.44 ? 403 PHE B CA 1 ATOM 6358 C C . PHE B 2 371 ? 58.695 -28.300 16.540 1.00 34.83 ? 403 PHE B C 1 ATOM 6359 O O . PHE B 2 371 ? 58.989 -28.658 15.394 1.00 38.96 ? 403 PHE B O 1 ATOM 6360 C CB . PHE B 2 371 ? 60.642 -28.362 18.021 1.00 32.98 ? 403 PHE B CB 1 ATOM 6361 C CG . PHE B 2 371 ? 61.345 -29.320 17.092 1.00 31.58 ? 403 PHE B CG 1 ATOM 6362 C CD1 . PHE B 2 371 ? 62.418 -28.887 16.307 1.00 30.65 ? 403 PHE B CD1 1 ATOM 6363 C CD2 . PHE B 2 371 ? 60.914 -30.653 16.989 1.00 30.17 ? 403 PHE B CD2 1 ATOM 6364 C CE1 . PHE B 2 371 ? 63.039 -29.769 15.440 1.00 30.40 ? 403 PHE B CE1 1 ATOM 6365 C CE2 . PHE B 2 371 ? 61.524 -31.527 16.128 1.00 29.14 ? 403 PHE B CE2 1 ATOM 6366 C CZ . PHE B 2 371 ? 62.585 -31.086 15.349 1.00 30.24 ? 403 PHE B CZ 1 ATOM 6367 N N . ILE B 2 372 ? 57.564 -28.660 17.141 1.00 35.51 ? 404 ILE B N 1 ATOM 6368 C CA . ILE B 2 372 ? 56.568 -29.447 16.403 1.00 37.62 ? 404 ILE B CA 1 ATOM 6369 C C . ILE B 2 372 ? 56.086 -28.611 15.214 1.00 35.66 ? 404 ILE B C 1 ATOM 6370 O O . ILE B 2 372 ? 55.973 -29.143 14.109 1.00 33.81 ? 404 ILE B O 1 ATOM 6371 C CB . ILE B 2 372 ? 55.332 -29.925 17.231 1.00 40.64 ? 404 ILE B CB 1 ATOM 6372 C CG1 . ILE B 2 372 ? 55.707 -30.510 18.625 1.00 41.37 ? 404 ILE B CG1 1 ATOM 6373 C CG2 . ILE B 2 372 ? 54.507 -30.933 16.413 1.00 41.09 ? 404 ILE B CG2 1 ATOM 6374 C CD1 . ILE B 2 372 ? 56.302 -31.905 18.651 1.00 40.91 ? 404 ILE B CD1 1 ATOM 6375 N N . LYS B 2 373 ? 55.824 -27.313 15.432 1.00 35.31 ? 405 LYS B N 1 ATOM 6376 C CA . LYS B 2 373 ? 55.430 -26.405 14.324 1.00 36.34 ? 405 LYS B CA 1 ATOM 6377 C C . LYS B 2 373 ? 56.509 -26.361 13.243 1.00 32.21 ? 405 LYS B C 1 ATOM 6378 O O . LYS B 2 373 ? 56.242 -26.598 12.046 1.00 28.36 ? 405 LYS B O 1 ATOM 6379 C CB . LYS B 2 373 ? 55.207 -24.973 14.814 1.00 39.08 ? 405 LYS B CB 1 ATOM 6380 C CG . LYS B 2 373 ? 53.931 -24.740 15.577 1.00 42.98 ? 405 LYS B CG 1 ATOM 6381 C CD . LYS B 2 373 ? 53.727 -23.249 15.771 1.00 47.58 ? 405 LYS B CD 1 ATOM 6382 C CE . LYS B 2 373 ? 52.748 -22.974 16.902 1.00 51.55 ? 405 LYS B CE 1 ATOM 6383 N NZ . LYS B 2 373 ? 51.970 -21.741 16.609 1.00 53.38 1 405 LYS B NZ 1 ATOM 6384 N N . TYR B 2 374 ? 57.721 -26.046 13.705 1.00 27.90 ? 406 TYR B N 1 ATOM 6385 C CA . TYR B 2 374 ? 58.877 -25.985 12.862 1.00 26.15 ? 406 TYR B CA 1 ATOM 6386 C C . TYR B 2 374 ? 58.947 -27.206 11.982 1.00 27.32 ? 406 TYR B C 1 ATOM 6387 O O . TYR B 2 374 ? 59.217 -27.105 10.776 1.00 27.06 ? 406 TYR B O 1 ATOM 6388 C CB . TYR B 2 374 ? 60.139 -25.902 13.697 1.00 24.63 ? 406 TYR B CB 1 ATOM 6389 C CG . TYR B 2 374 ? 61.398 -25.693 12.874 1.00 23.96 ? 406 TYR B CG 1 ATOM 6390 C CD1 . TYR B 2 374 ? 61.795 -24.423 12.492 1.00 24.12 ? 406 TYR B CD1 1 ATOM 6391 C CD2 . TYR B 2 374 ? 62.191 -26.764 12.473 1.00 22.96 ? 406 TYR B CD2 1 ATOM 6392 C CE1 . TYR B 2 374 ? 62.932 -24.231 11.736 1.00 23.47 ? 406 TYR B CE1 1 ATOM 6393 C CE2 . TYR B 2 374 ? 63.334 -26.566 11.722 1.00 21.63 ? 406 TYR B CE2 1 ATOM 6394 C CZ . TYR B 2 374 ? 63.686 -25.297 11.358 1.00 21.59 ? 406 TYR B CZ 1 ATOM 6395 O OH . TYR B 2 374 ? 64.795 -25.060 10.622 1.00 20.06 ? 406 TYR B OH 1 ATOM 6396 N N . TYR B 2 375 ? 58.699 -28.366 12.571 1.00 28.21 ? 407 TYR B N 1 ATOM 6397 C CA . TYR B 2 375 ? 58.859 -29.603 11.829 1.00 30.59 ? 407 TYR B CA 1 ATOM 6398 C C . TYR B 2 375 ? 57.697 -29.899 10.873 1.00 34.85 ? 407 TYR B C 1 ATOM 6399 O O . TYR B 2 375 ? 57.877 -30.624 9.897 1.00 36.70 ? 407 TYR B O 1 ATOM 6400 C CB . TYR B 2 375 ? 59.088 -30.756 12.788 1.00 30.24 ? 407 TYR B CB 1 ATOM 6401 C CG . TYR B 2 375 ? 59.744 -31.954 12.144 1.00 30.04 ? 407 TYR B CG 1 ATOM 6402 C CD1 . TYR B 2 375 ? 61.084 -31.939 11.802 1.00 30.59 ? 407 TYR B CD1 1 ATOM 6403 C CD2 . TYR B 2 375 ? 59.028 -33.110 11.897 1.00 30.20 ? 407 TYR B CD2 1 ATOM 6404 C CE1 . TYR B 2 375 ? 61.677 -33.047 11.207 1.00 31.05 ? 407 TYR B CE1 1 ATOM 6405 C CE2 . TYR B 2 375 ? 59.621 -34.220 11.329 1.00 30.27 ? 407 TYR B CE2 1 ATOM 6406 C CZ . TYR B 2 375 ? 60.938 -34.184 10.983 1.00 30.03 ? 407 TYR B CZ 1 ATOM 6407 O OH . TYR B 2 375 ? 61.505 -35.295 10.430 1.00 30.00 ? 407 TYR B OH 1 ATOM 6408 N N . ASN B 2 376 ? 56.507 -29.370 11.159 1.00 38.92 ? 408 ASN B N 1 ATOM 6409 C CA . ASN B 2 376 ? 55.430 -29.379 10.178 1.00 41.24 ? 408 ASN B CA 1 ATOM 6410 C C . ASN B 2 376 ? 55.899 -28.524 9.038 1.00 38.73 ? 408 ASN B C 1 ATOM 6411 O O . ASN B 2 376 ? 56.013 -28.986 7.902 1.00 38.42 ? 408 ASN B O 1 ATOM 6412 C CB . ASN B 2 376 ? 54.137 -28.763 10.747 1.00 48.84 ? 408 ASN B CB 1 ATOM 6413 C CG . ASN B 2 376 ? 52.967 -29.738 10.768 1.00 53.47 ? 408 ASN B CG 1 ATOM 6414 O OD1 . ASN B 2 376 ? 52.465 -30.164 9.707 1.00 55.25 ? 408 ASN B OD1 1 ATOM 6415 N ND2 . ASN B 2 376 ? 52.501 -30.073 11.980 1.00 54.24 ? 408 ASN B ND2 1 ATOM 6416 N N . TYR B 2 377 ? 56.191 -27.269 9.376 1.00 36.38 ? 409 TYR B N 1 ATOM 6417 C CA . TYR B 2 377 ? 56.504 -26.261 8.385 1.00 35.46 ? 409 TYR B CA 1 ATOM 6418 C C . TYR B 2 377 ? 57.668 -26.716 7.568 1.00 32.30 ? 409 TYR B C 1 ATOM 6419 O O . TYR B 2 377 ? 57.730 -26.437 6.389 1.00 31.96 ? 409 TYR B O 1 ATOM 6420 C CB . TYR B 2 377 ? 56.822 -24.910 9.038 1.00 37.06 ? 409 TYR B CB 1 ATOM 6421 C CG . TYR B 2 377 ? 55.636 -24.210 9.688 1.00 38.58 ? 409 TYR B CG 1 ATOM 6422 C CD1 . TYR B 2 377 ? 54.334 -24.681 9.515 1.00 38.77 ? 409 TYR B CD1 1 ATOM 6423 C CD2 . TYR B 2 377 ? 55.814 -23.054 10.460 1.00 39.65 ? 409 TYR B CD2 1 ATOM 6424 C CE1 . TYR B 2 377 ? 53.258 -24.045 10.105 1.00 38.86 ? 409 TYR B CE1 1 ATOM 6425 C CE2 . TYR B 2 377 ? 54.734 -22.420 11.056 1.00 40.06 ? 409 TYR B CE2 1 ATOM 6426 C CZ . TYR B 2 377 ? 53.461 -22.927 10.870 1.00 38.78 ? 409 TYR B CZ 1 ATOM 6427 O OH . TYR B 2 377 ? 52.372 -22.320 11.431 1.00 40.33 ? 409 TYR B OH 1 ATOM 6428 N N . PHE B 2 378 ? 58.576 -27.438 8.203 1.00 31.10 ? 410 PHE B N 1 ATOM 6429 C CA . PHE B 2 378 ? 59.769 -27.958 7.533 1.00 31.25 ? 410 PHE B CA 1 ATOM 6430 C C . PHE B 2 378 ? 59.491 -28.685 6.209 1.00 32.14 ? 410 PHE B C 1 ATOM 6431 O O . PHE B 2 378 ? 60.216 -28.490 5.226 1.00 32.23 ? 410 PHE B O 1 ATOM 6432 C CB . PHE B 2 378 ? 60.525 -28.881 8.469 1.00 28.42 ? 410 PHE B CB 1 ATOM 6433 C CG . PHE B 2 378 ? 61.679 -29.553 7.833 1.00 26.57 ? 410 PHE B CG 1 ATOM 6434 C CD1 . PHE B 2 378 ? 62.816 -28.846 7.559 1.00 26.52 ? 410 PHE B CD1 1 ATOM 6435 C CD2 . PHE B 2 378 ? 61.624 -30.895 7.497 1.00 26.46 ? 410 PHE B CD2 1 ATOM 6436 C CE1 . PHE B 2 378 ? 63.921 -29.466 6.991 1.00 27.22 ? 410 PHE B CE1 1 ATOM 6437 C CE2 . PHE B 2 378 ? 62.708 -31.521 6.916 1.00 26.77 ? 410 PHE B CE2 1 ATOM 6438 C CZ . PHE B 2 378 ? 63.867 -30.806 6.666 1.00 26.99 ? 410 PHE B CZ 1 ATOM 6439 N N . PHE B 2 379 ? 58.450 -29.520 6.193 1.00 32.84 ? 411 PHE B N 1 ATOM 6440 C CA . PHE B 2 379 ? 57.971 -30.161 4.953 1.00 33.03 ? 411 PHE B CA 1 ATOM 6441 C C . PHE B 2 379 ? 56.856 -29.315 4.316 1.00 30.73 ? 411 PHE B C 1 ATOM 6442 O O . PHE B 2 379 ? 56.042 -29.834 3.547 1.00 28.32 ? 411 PHE B O 1 ATOM 6443 C CB . PHE B 2 379 ? 57.446 -31.588 5.232 1.00 34.03 ? 411 PHE B CB 1 ATOM 6444 C CG . PHE B 2 379 ? 58.495 -32.563 5.744 1.00 35.80 ? 411 PHE B CG 1 ATOM 6445 C CD1 . PHE B 2 379 ? 59.486 -33.079 4.900 1.00 36.73 ? 411 PHE B CD1 1 ATOM 6446 C CD2 . PHE B 2 379 ? 58.476 -32.993 7.064 1.00 36.90 ? 411 PHE B CD2 1 ATOM 6447 C CE1 . PHE B 2 379 ? 60.439 -33.986 5.378 1.00 36.11 ? 411 PHE B CE1 1 ATOM 6448 C CE2 . PHE B 2 379 ? 59.427 -33.901 7.538 1.00 37.12 ? 411 PHE B CE2 1 ATOM 6449 C CZ . PHE B 2 379 ? 60.398 -34.406 6.689 1.00 36.32 ? 411 PHE B CZ 1 ATOM 6450 N N . VAL B 2 380 ? 56.826 -28.019 4.651 1.00 29.05 ? 412 VAL B N 1 ATOM 6451 C CA . VAL B 2 380 ? 55.832 -27.094 4.140 1.00 27.15 ? 412 VAL B CA 1 ATOM 6452 C C . VAL B 2 380 ? 54.442 -27.742 4.240 1.00 28.26 ? 412 VAL B C 1 ATOM 6453 O O . VAL B 2 380 ? 53.717 -27.904 3.247 1.00 25.90 ? 412 VAL B O 1 ATOM 6454 C CB . VAL B 2 380 ? 56.186 -26.682 2.716 1.00 26.12 ? 412 VAL B CB 1 ATOM 6455 C CG1 . VAL B 2 380 ? 55.381 -25.467 2.299 1.00 25.94 ? 412 VAL B CG1 1 ATOM 6456 C CG2 . VAL B 2 380 ? 57.687 -26.432 2.615 1.00 25.75 ? 412 VAL B CG2 1 ATOM 6457 N N . SER B 2 381 ? 54.117 -28.149 5.474 1.00 28.95 ? 413 SER B N 1 ATOM 6458 C CA . SER B 2 381 ? 52.775 -28.606 5.862 1.00 29.27 ? 413 SER B CA 1 ATOM 6459 C C . SER B 2 381 ? 52.308 -29.822 5.063 1.00 31.47 ? 413 SER B C 1 ATOM 6460 O O . SER B 2 381 ? 51.106 -30.072 4.932 1.00 31.23 ? 413 SER B O 1 ATOM 6461 C CB . SER B 2 381 ? 51.750 -27.450 5.771 1.00 27.83 ? 413 SER B CB 1 ATOM 6462 O OG . SER B 2 381 ? 51.940 -26.502 6.815 1.00 25.75 ? 413 SER B OG 1 ATOM 6463 N N . TYR B 2 382 ? 53.262 -30.604 4.568 1.00 34.52 ? 414 TYR B N 1 ATOM 6464 C CA . TYR B 2 382 ? 52.934 -31.744 3.715 1.00 36.60 ? 414 TYR B CA 1 ATOM 6465 C C . TYR B 2 382 ? 52.166 -32.836 4.450 1.00 42.56 ? 414 TYR B C 1 ATOM 6466 O O . TYR B 2 382 ? 51.190 -33.370 3.907 1.00 46.00 ? 414 TYR B O 1 ATOM 6467 C CB . TYR B 2 382 ? 54.184 -32.338 3.061 1.00 33.17 ? 414 TYR B CB 1 ATOM 6468 C CG . TYR B 2 382 ? 53.883 -33.575 2.243 1.00 30.15 ? 414 TYR B CG 1 ATOM 6469 C CD1 . TYR B 2 382 ? 53.283 -33.477 0.999 1.00 28.05 ? 414 TYR B CD1 1 ATOM 6470 C CD2 . TYR B 2 382 ? 54.182 -34.840 2.737 1.00 29.18 ? 414 TYR B CD2 1 ATOM 6471 C CE1 . TYR B 2 382 ? 53.004 -34.598 0.270 1.00 27.44 ? 414 TYR B CE1 1 ATOM 6472 C CE2 . TYR B 2 382 ? 53.908 -35.964 2.014 1.00 27.93 ? 414 TYR B CE2 1 ATOM 6473 C CZ . TYR B 2 382 ? 53.319 -35.833 0.783 1.00 27.24 ? 414 TYR B CZ 1 ATOM 6474 O OH . TYR B 2 382 ? 53.041 -36.963 0.072 1.00 28.04 ? 414 TYR B OH 1 ATOM 6475 N N . ASP B 2 383 ? 52.614 -33.187 5.653 1.00 47.63 ? 415 ASP B N 1 ATOM 6476 C CA . ASP B 2 383 ? 51.842 -34.079 6.496 1.00 56.44 ? 415 ASP B CA 1 ATOM 6477 C C . ASP B 2 383 ? 51.456 -33.276 7.735 1.00 64.33 ? 415 ASP B C 1 ATOM 6478 O O . ASP B 2 383 ? 52.323 -32.772 8.462 1.00 66.70 ? 415 ASP B O 1 ATOM 6479 C CB . ASP B 2 383 ? 52.635 -35.349 6.837 1.00 61.12 ? 415 ASP B CB 1 ATOM 6480 C CG . ASP B 2 383 ? 51.804 -36.394 7.609 1.00 63.84 ? 415 ASP B CG 1 ATOM 6481 O OD1 . ASP B 2 383 ? 50.560 -36.279 7.610 1.00 64.63 ? 415 ASP B OD1 1 ATOM 6482 O OD2 . ASP B 2 383 ? 52.393 -37.340 8.201 1.00 61.98 -1 415 ASP B OD2 1 ATOM 6483 N N . SER B 2 384 ? 50.144 -33.119 7.931 1.00 68.57 ? 416 SER B N 1 ATOM 6484 C CA . SER B 2 384 ? 49.612 -32.404 9.081 1.00 68.94 ? 416 SER B CA 1 ATOM 6485 C C . SER B 2 384 ? 49.733 -33.290 10.276 1.00 63.46 ? 416 SER B C 1 ATOM 6486 O O . SER B 2 384 ? 49.676 -32.812 11.400 1.00 68.58 ? 416 SER B O 1 ATOM 6487 C CB . SER B 2 384 ? 48.141 -31.995 8.893 1.00 75.12 ? 416 SER B CB 1 ATOM 6488 O OG . SER B 2 384 ? 47.985 -30.576 8.845 1.00 79.96 ? 416 SER B OG 1 ATOM 6489 N N . SER B 2 385 ? 49.872 -34.586 10.032 1.00 59.17 ? 417 SER B N 1 ATOM 6490 C CA . SER B 2 385 ? 50.110 -35.539 11.101 1.00 59.80 ? 417 SER B CA 1 ATOM 6491 C C . SER B 2 385 ? 51.429 -36.257 10.885 1.00 57.66 ? 417 SER B C 1 ATOM 6492 O O . SER B 2 385 ? 51.474 -37.491 10.780 1.00 57.04 ? 417 SER B O 1 ATOM 6493 C CB . SER B 2 385 ? 48.963 -36.544 11.183 1.00 60.27 ? 417 SER B CB 1 ATOM 6494 O OG . SER B 2 385 ? 48.998 -37.423 10.079 1.00 64.02 ? 417 SER B OG 1 ATOM 6495 N N . VAL B 2 386 ? 52.500 -35.474 10.808 1.00 56.57 ? 418 VAL B N 1 ATOM 6496 C CA . VAL B 2 386 ? 53.859 -36.027 10.812 1.00 58.60 ? 418 VAL B CA 1 ATOM 6497 C C . VAL B 2 386 ? 54.435 -35.988 12.244 1.00 57.02 ? 418 VAL B C 1 ATOM 6498 O O . VAL B 2 386 ? 53.914 -35.284 13.107 1.00 58.05 ? 418 VAL B O 1 ATOM 6499 C CB . VAL B 2 386 ? 54.772 -35.283 9.804 1.00 57.64 ? 418 VAL B CB 1 ATOM 6500 C CG1 . VAL B 2 386 ? 55.494 -34.110 10.454 1.00 57.56 ? 418 VAL B CG1 1 ATOM 6501 C CG2 . VAL B 2 386 ? 55.765 -36.244 9.167 1.00 58.15 ? 418 VAL B CG2 1 ATOM 6502 N N . THR B 2 387 ? 55.490 -36.753 12.505 1.00 53.04 ? 419 THR B N 1 ATOM 6503 C CA . THR B 2 387 ? 56.077 -36.805 13.849 1.00 48.52 ? 419 THR B CA 1 ATOM 6504 C C . THR B 2 387 ? 57.603 -36.860 13.761 1.00 44.45 ? 419 THR B C 1 ATOM 6505 O O . THR B 2 387 ? 58.166 -36.793 12.670 1.00 43.18 ? 419 THR B O 1 ATOM 6506 C CB . THR B 2 387 ? 55.485 -37.985 14.666 1.00 48.92 ? 419 THR B CB 1 ATOM 6507 O OG1 . THR B 2 387 ? 56.045 -37.991 15.988 1.00 48.54 ? 419 THR B OG1 1 ATOM 6508 C CG2 . THR B 2 387 ? 55.709 -39.354 13.961 1.00 46.81 ? 419 THR B CG2 1 ATOM 6509 N N . CYS B 2 388 ? 58.279 -36.963 14.897 1.00 41.86 ? 420 CYS B N 1 ATOM 6510 C CA . CYS B 2 388 ? 59.735 -36.881 14.895 1.00 42.35 ? 420 CYS B CA 1 ATOM 6511 C C . CYS B 2 388 ? 60.336 -37.432 16.179 1.00 43.09 ? 420 CYS B C 1 ATOM 6512 O O . CYS B 2 388 ? 60.027 -36.933 17.251 1.00 44.96 ? 420 CYS B O 1 ATOM 6513 C CB . CYS B 2 388 ? 60.178 -35.420 14.714 1.00 40.42 ? 420 CYS B CB 1 ATOM 6514 S SG . CYS B 2 388 ? 61.952 -35.196 14.447 1.00 38.82 ? 420 CYS B SG 1 ATOM 6515 N N . ASP B 2 389 ? 61.198 -38.442 16.069 1.00 42.49 ? 421 ASP B N 1 ATOM 6516 C CA . ASP B 2 389 ? 61.876 -39.003 17.254 1.00 42.36 ? 421 ASP B CA 1 ATOM 6517 C C . ASP B 2 389 ? 63.079 -38.141 17.760 1.00 39.43 ? 421 ASP B C 1 ATOM 6518 O O . ASP B 2 389 ? 63.435 -37.122 17.141 1.00 35.32 ? 421 ASP B O 1 ATOM 6519 C CB . ASP B 2 389 ? 62.288 -40.465 16.992 1.00 42.86 ? 421 ASP B CB 1 ATOM 6520 C CG . ASP B 2 389 ? 63.396 -40.590 15.982 1.00 43.99 ? 421 ASP B CG 1 ATOM 6521 O OD1 . ASP B 2 389 ? 63.413 -39.753 15.059 1.00 50.88 ? 421 ASP B OD1 1 ATOM 6522 O OD2 . ASP B 2 389 ? 64.235 -41.513 16.097 1.00 41.53 -1 421 ASP B OD2 1 ATOM 6523 N N . LYS B 2 390 ? 63.678 -38.558 18.884 1.00 37.16 ? 422 LYS B N 1 ATOM 6524 C CA . LYS B 2 390 ? 64.699 -37.765 19.570 1.00 38.18 ? 422 LYS B CA 1 ATOM 6525 C C . LYS B 2 390 ? 65.905 -37.525 18.691 1.00 39.07 ? 422 LYS B C 1 ATOM 6526 O O . LYS B 2 390 ? 66.590 -36.512 18.834 1.00 38.69 ? 422 LYS B O 1 ATOM 6527 C CB . LYS B 2 390 ? 65.246 -38.451 20.819 1.00 39.94 ? 422 LYS B CB 1 ATOM 6528 C CG . LYS B 2 390 ? 64.263 -38.879 21.896 1.00 43.01 ? 422 LYS B CG 1 ATOM 6529 C CD . LYS B 2 390 ? 64.830 -40.101 22.644 1.00 46.87 ? 422 LYS B CD 1 ATOM 6530 C CE . LYS B 2 390 ? 65.162 -41.279 21.699 1.00 45.10 ? 422 LYS B CE 1 ATOM 6531 N NZ . LYS B 2 390 ? 65.191 -42.635 22.316 1.00 42.73 1 422 LYS B NZ 1 ATOM 6532 N N . THR B 2 391 ? 66.214 -38.490 17.832 1.00 38.98 ? 423 THR B N 1 ATOM 6533 C CA . THR B 2 391 ? 67.444 -38.435 17.058 1.00 38.23 ? 423 THR B CA 1 ATOM 6534 C C . THR B 2 391 ? 67.254 -37.427 15.930 1.00 36.84 ? 423 THR B C 1 ATOM 6535 O O . THR B 2 391 ? 68.086 -36.528 15.753 1.00 35.33 ? 423 THR B O 1 ATOM 6536 C CB . THR B 2 391 ? 67.832 -39.828 16.500 1.00 39.02 ? 423 THR B CB 1 ATOM 6537 O OG1 . THR B 2 391 ? 67.425 -40.842 17.423 1.00 39.17 ? 423 THR B OG1 1 ATOM 6538 C CG2 . THR B 2 391 ? 69.344 -39.938 16.259 1.00 38.38 ? 423 THR B CG2 1 ATOM 6539 N N . CYS B 2 392 ? 66.154 -37.566 15.186 1.00 35.77 ? 424 CYS B N 1 ATOM 6540 C CA . CYS B 2 392 ? 65.866 -36.661 14.059 1.00 38.03 ? 424 CYS B CA 1 ATOM 6541 C C . CYS B 2 392 ? 65.794 -35.206 14.524 1.00 36.29 ? 424 CYS B C 1 ATOM 6542 O O . CYS B 2 392 ? 66.200 -34.303 13.790 1.00 35.09 ? 424 CYS B O 1 ATOM 6543 C CB . CYS B 2 392 ? 64.565 -37.045 13.316 1.00 39.48 ? 424 CYS B CB 1 ATOM 6544 S SG . CYS B 2 392 ? 64.765 -38.283 11.999 1.00 42.54 ? 424 CYS B SG 1 ATOM 6545 N N . LYS B 2 393 ? 65.283 -35.012 15.746 1.00 33.39 ? 425 LYS B N 1 ATOM 6546 C CA . LYS B 2 393 ? 65.171 -33.695 16.358 1.00 31.15 ? 425 LYS B CA 1 ATOM 6547 C C . LYS B 2 393 ? 66.518 -33.144 16.770 1.00 30.23 ? 425 LYS B C 1 ATOM 6548 O O . LYS B 2 393 ? 66.799 -31.992 16.546 1.00 29.70 ? 425 LYS B O 1 ATOM 6549 C CB . LYS B 2 393 ? 64.236 -33.726 17.579 1.00 30.83 ? 425 LYS B CB 1 ATOM 6550 C CG . LYS B 2 393 ? 64.278 -32.450 18.424 1.00 29.98 ? 425 LYS B CG 1 ATOM 6551 C CD . LYS B 2 393 ? 62.995 -32.232 19.196 1.00 29.39 ? 425 LYS B CD 1 ATOM 6552 C CE . LYS B 2 393 ? 63.239 -31.403 20.449 1.00 29.35 ? 425 LYS B CE 1 ATOM 6553 N NZ . LYS B 2 393 ? 61.943 -31.087 21.103 1.00 29.37 1 425 LYS B NZ 1 ATOM 6554 N N . ALA B 2 394 ? 67.340 -33.957 17.410 1.00 31.34 ? 426 ALA B N 1 ATOM 6555 C CA . ALA B 2 394 ? 68.700 -33.554 17.701 1.00 31.23 ? 426 ALA B CA 1 ATOM 6556 C C . ALA B 2 394 ? 69.409 -33.168 16.391 1.00 32.35 ? 426 ALA B C 1 ATOM 6557 O O . ALA B 2 394 ? 70.132 -32.177 16.339 1.00 31.81 ? 426 ALA B O 1 ATOM 6558 C CB . ALA B 2 394 ? 69.433 -34.680 18.405 1.00 31.14 ? 426 ALA B CB 1 ATOM 6559 N N . PHE B 2 395 ? 69.178 -33.924 15.323 1.00 33.57 ? 427 PHE B N 1 ATOM 6560 C CA . PHE B 2 395 ? 69.789 -33.592 14.041 1.00 36.01 ? 427 PHE B CA 1 ATOM 6561 C C . PHE B 2 395 ? 69.368 -32.233 13.457 1.00 36.22 ? 427 PHE B C 1 ATOM 6562 O O . PHE B 2 395 ? 70.129 -31.648 12.658 1.00 38.06 ? 427 PHE B O 1 ATOM 6563 C CB . PHE B 2 395 ? 69.572 -34.720 13.024 1.00 36.58 ? 427 PHE B CB 1 ATOM 6564 C CG . PHE B 2 395 ? 70.351 -35.978 13.343 1.00 38.16 ? 427 PHE B CG 1 ATOM 6565 C CD1 . PHE B 2 395 ? 71.579 -35.925 14.052 1.00 37.06 ? 427 PHE B CD1 1 ATOM 6566 C CD2 . PHE B 2 395 ? 69.871 -37.222 12.919 1.00 37.50 ? 427 PHE B CD2 1 ATOM 6567 C CE1 . PHE B 2 395 ? 72.276 -37.081 14.349 1.00 36.50 ? 427 PHE B CE1 1 ATOM 6568 C CE2 . PHE B 2 395 ? 70.568 -38.377 13.214 1.00 37.15 ? 427 PHE B CE2 1 ATOM 6569 C CZ . PHE B 2 395 ? 71.770 -38.305 13.932 1.00 37.95 ? 427 PHE B CZ 1 ATOM 6570 N N . GLN B 2 396 ? 68.185 -31.755 13.856 1.00 34.66 ? 428 GLN B N 1 ATOM 6571 C CA . GLN B 2 396 ? 67.653 -30.445 13.457 1.00 35.53 ? 428 GLN B CA 1 ATOM 6572 C C . GLN B 2 396 ? 68.183 -29.330 14.365 1.00 37.76 ? 428 GLN B C 1 ATOM 6573 O O . GLN B 2 396 ? 68.632 -28.285 13.888 1.00 36.93 ? 428 GLN B O 1 ATOM 6574 C CB . GLN B 2 396 ? 66.110 -30.428 13.525 1.00 35.72 ? 428 GLN B CB 1 ATOM 6575 C CG . GLN B 2 396 ? 65.368 -31.314 12.520 1.00 35.86 ? 428 GLN B CG 1 ATOM 6576 C CD . GLN B 2 396 ? 65.063 -30.637 11.191 1.00 35.34 ? 428 GLN B CD 1 ATOM 6577 O OE1 . GLN B 2 396 ? 65.373 -29.466 10.991 1.00 36.06 ? 428 GLN B OE1 1 ATOM 6578 N NE2 . GLN B 2 396 ? 64.467 -31.382 10.269 1.00 34.86 ? 428 GLN B NE2 1 ATOM 6579 N N . ILE B 2 397 ? 68.118 -29.553 15.680 1.00 41.02 ? 429 ILE B N 1 ATOM 6580 C CA . ILE B 2 397 ? 68.489 -28.530 16.679 1.00 41.77 ? 429 ILE B CA 1 ATOM 6581 C C . ILE B 2 397 ? 69.942 -28.146 16.486 1.00 40.94 ? 429 ILE B C 1 ATOM 6582 O O . ILE B 2 397 ? 70.279 -26.977 16.419 1.00 42.84 ? 429 ILE B O 1 ATOM 6583 C CB . ILE B 2 397 ? 68.312 -29.007 18.159 1.00 43.28 ? 429 ILE B CB 1 ATOM 6584 C CG1 . ILE B 2 397 ? 66.847 -29.392 18.478 1.00 43.71 ? 429 ILE B CG1 1 ATOM 6585 C CG2 . ILE B 2 397 ? 68.818 -27.944 19.141 1.00 42.47 ? 429 ILE B CG2 1 ATOM 6586 C CD1 . ILE B 2 397 ? 65.819 -28.310 18.242 1.00 43.48 ? 429 ILE B CD1 1 ATOM 6587 N N . CYS B 2 398 ? 70.765 -29.155 16.447 1.00 40.40 ? 430 CYS B N 1 ATOM 6588 C CA . CYS B 2 398 ? 72.156 -28.927 16.330 1.00 41.73 ? 430 CYS B CA 1 ATOM 6589 C C . CYS B 2 398 ? 72.544 -28.405 14.953 1.00 38.80 ? 430 CYS B C 1 ATOM 6590 O O . CYS B 2 398 ? 73.694 -28.228 14.716 1.00 42.65 ? 430 CYS B O 1 ATOM 6591 C CB . CYS B 2 398 ? 72.973 -30.148 16.861 1.00 44.66 ? 430 CYS B CB 1 ATOM 6592 S SG . CYS B 2 398 ? 73.679 -29.994 18.546 1.00 51.21 ? 430 CYS B SG 1 ATOM 6593 N N . ALA B 2 399 ? 71.604 -28.144 14.053 1.00 34.03 ? 431 ALA B N 1 ATOM 6594 C CA . ALA B 2 399 ? 71.958 -27.612 12.766 1.00 29.83 ? 431 ALA B CA 1 ATOM 6595 C C . ALA B 2 399 ? 71.502 -26.242 12.642 1.00 28.02 ? 431 ALA B C 1 ATOM 6596 O O . ALA B 2 399 ? 72.061 -25.497 11.924 1.00 25.47 ? 431 ALA B O 1 ATOM 6597 C CB . ALA B 2 399 ? 71.361 -28.453 11.684 1.00 29.19 ? 431 ALA B CB 1 ATOM 6598 N N . ILE B 2 400 ? 70.466 -25.910 13.360 1.00 29.36 ? 432 ILE B N 1 ATOM 6599 C CA . ILE B 2 400 ? 69.914 -24.582 13.360 1.00 30.45 ? 432 ILE B CA 1 ATOM 6600 C C . ILE B 2 400 ? 70.829 -23.712 14.149 1.00 30.75 ? 432 ILE B C 1 ATOM 6601 O O . ILE B 2 400 ? 70.948 -22.569 13.897 1.00 30.34 ? 432 ILE B O 1 ATOM 6602 C CB . ILE B 2 400 ? 68.542 -24.557 14.048 1.00 28.47 ? 432 ILE B CB 1 ATOM 6603 C CG1 . ILE B 2 400 ? 67.693 -25.717 13.583 1.00 27.77 ? 432 ILE B CG1 1 ATOM 6604 C CG2 . ILE B 2 400 ? 67.835 -23.249 13.825 1.00 27.51 ? 432 ILE B CG2 1 ATOM 6605 C CD1 . ILE B 2 400 ? 66.248 -25.611 13.953 1.00 27.53 ? 432 ILE B CD1 1 ATOM 6606 N N . MET B 2 401 ? 71.492 -24.288 15.119 1.00 33.63 ? 433 MET B N 1 ATOM 6607 C CA . MET B 2 401 ? 72.356 -23.560 15.995 1.00 36.27 ? 433 MET B CA 1 ATOM 6608 C C . MET B 2 401 ? 73.819 -23.670 15.753 1.00 33.93 ? 433 MET B C 1 ATOM 6609 O O . MET B 2 401 ? 74.524 -22.772 16.090 1.00 34.98 ? 433 MET B O 1 ATOM 6610 C CB . MET B 2 401 ? 72.088 -23.985 17.421 1.00 39.59 ? 433 MET B CB 1 ATOM 6611 C CG . MET B 2 401 ? 71.087 -23.145 18.170 1.00 40.97 ? 433 MET B CG 1 ATOM 6612 S SD . MET B 2 401 ? 70.240 -24.172 19.327 1.00 45.49 ? 433 MET B SD 1 ATOM 6613 C CE . MET B 2 401 ? 70.635 -23.317 20.825 1.00 44.49 ? 433 MET B CE 1 ATOM 6614 N N . ASN B 2 402 ? 74.291 -24.759 15.187 1.00 33.30 ? 434 ASN B N 1 ATOM 6615 C CA . ASN B 2 402 ? 75.708 -24.914 14.927 1.00 33.95 ? 434 ASN B CA 1 ATOM 6616 C C . ASN B 2 402 ? 76.049 -24.975 13.457 1.00 33.41 ? 434 ASN B C 1 ATOM 6617 O O . ASN B 2 402 ? 75.497 -25.758 12.745 1.00 29.63 ? 434 ASN B O 1 ATOM 6618 C CB . ASN B 2 402 ? 76.198 -26.156 15.612 1.00 34.20 ? 434 ASN B CB 1 ATOM 6619 C CG . ASN B 2 402 ? 75.670 -26.290 16.999 1.00 33.83 ? 434 ASN B CG 1 ATOM 6620 O OD1 . ASN B 2 402 ? 76.085 -25.600 17.895 1.00 34.67 ? 434 ASN B OD1 1 ATOM 6621 N ND2 . ASN B 2 402 ? 74.757 -27.181 17.178 1.00 33.95 ? 434 ASN B ND2 1 ATOM 6622 N N . LEU B 2 403 ? 76.962 -24.140 13.001 1.00 35.01 ? 435 LEU B N 1 ATOM 6623 C CA . LEU B 2 403 ? 77.296 -24.113 11.597 1.00 37.12 ? 435 LEU B CA 1 ATOM 6624 C C . LEU B 2 403 ? 78.608 -24.750 11.240 1.00 43.48 ? 435 LEU B C 1 ATOM 6625 O O . LEU B 2 403 ? 78.712 -25.316 10.191 1.00 47.84 ? 435 LEU B O 1 ATOM 6626 C CB . LEU B 2 403 ? 77.176 -22.717 11.043 1.00 35.79 ? 435 LEU B CB 1 ATOM 6627 C CG . LEU B 2 403 ? 75.785 -22.367 10.568 1.00 35.67 ? 435 LEU B CG 1 ATOM 6628 C CD1 . LEU B 2 403 ? 74.834 -22.248 11.707 1.00 36.29 ? 435 LEU B CD1 1 ATOM 6629 C CD2 . LEU B 2 403 ? 75.762 -21.095 9.795 1.00 35.39 ? 435 LEU B CD2 1 ATOM 6630 N N . ASP B 2 404 ? 79.607 -24.672 12.113 1.00 49.74 ? 436 ASP B N 1 ATOM 6631 C CA . ASP B 2 404 ? 80.906 -25.296 11.883 1.00 52.43 ? 436 ASP B CA 1 ATOM 6632 C C . ASP B 2 404 ? 80.980 -26.596 12.650 1.00 49.47 ? 436 ASP B C 1 ATOM 6633 O O . ASP B 2 404 ? 80.054 -26.912 13.321 1.00 48.36 ? 436 ASP B O 1 ATOM 6634 C CB . ASP B 2 404 ? 82.040 -24.363 12.226 1.00 54.10 ? 436 ASP B CB 1 ATOM 6635 C CG . ASP B 2 404 ? 81.856 -23.684 13.522 1.00 57.70 ? 436 ASP B CG 1 ATOM 6636 O OD1 . ASP B 2 404 ? 82.623 -23.993 14.426 1.00 61.61 ? 436 ASP B OD1 1 ATOM 6637 O OD2 . ASP B 2 404 ? 80.987 -22.821 13.640 1.00 57.38 -1 436 ASP B OD2 1 ATOM 6638 N N . ASN B 2 405 ? 82.048 -27.370 12.541 1.00 49.66 ? 437 ASN B N 1 ATOM 6639 C CA . ASN B 2 405 ? 82.082 -28.682 13.195 1.00 53.65 ? 437 ASN B CA 1 ATOM 6640 C C . ASN B 2 405 ? 82.561 -28.826 14.600 1.00 52.59 ? 437 ASN B C 1 ATOM 6641 O O . ASN B 2 405 ? 82.390 -29.857 15.219 1.00 46.08 ? 437 ASN B O 1 ATOM 6642 C CB . ASN B 2 405 ? 82.728 -29.733 12.324 1.00 56.77 ? 437 ASN B CB 1 ATOM 6643 C CG . ASN B 2 405 ? 84.205 -29.777 12.483 1.00 58.28 ? 437 ASN B CG 1 ATOM 6644 O OD1 . ASN B 2 405 ? 84.791 -30.837 12.568 1.00 57.55 ? 437 ASN B OD1 1 ATOM 6645 N ND2 . ASN B 2 405 ? 84.816 -28.618 12.542 1.00 60.85 ? 437 ASN B ND2 1 ATOM 6646 N N . ILE B 2 406 ? 83.159 -27.778 15.103 1.00 55.14 ? 438 ILE B N 1 ATOM 6647 C CA . ILE B 2 406 ? 83.625 -27.788 16.443 1.00 57.61 ? 438 ILE B CA 1 ATOM 6648 C C . ILE B 2 406 ? 82.342 -27.625 17.177 1.00 56.00 ? 438 ILE B C 1 ATOM 6649 O O . ILE B 2 406 ? 82.012 -28.412 18.019 1.00 56.90 ? 438 ILE B O 1 ATOM 6650 C CB . ILE B 2 406 ? 84.554 -26.599 16.705 1.00 60.84 ? 438 ILE B CB 1 ATOM 6651 C CG1 . ILE B 2 406 ? 85.958 -26.948 16.283 1.00 59.78 ? 438 ILE B CG1 1 ATOM 6652 C CG2 . ILE B 2 406 ? 84.636 -26.274 18.177 1.00 63.23 ? 438 ILE B CG2 1 ATOM 6653 C CD1 . ILE B 2 406 ? 86.412 -28.250 16.866 1.00 59.39 ? 438 ILE B CD1 1 ATOM 6654 N N . SER B 2 407 ? 81.607 -26.593 16.833 1.00 51.24 ? 439 SER B N 1 ATOM 6655 C CA . SER B 2 407 ? 80.356 -26.349 17.474 1.00 50.23 ? 439 SER B CA 1 ATOM 6656 C C . SER B 2 407 ? 79.450 -27.527 17.309 1.00 47.34 ? 439 SER B C 1 ATOM 6657 O O . SER B 2 407 ? 79.028 -28.126 18.268 1.00 44.07 ? 439 SER B O 1 ATOM 6658 C CB . SER B 2 407 ? 79.734 -25.155 16.837 1.00 52.11 ? 439 SER B CB 1 ATOM 6659 O OG . SER B 2 407 ? 80.563 -24.736 15.801 1.00 56.75 ? 439 SER B OG 1 ATOM 6660 N N . TYR B 2 408 ? 79.153 -27.857 16.070 1.00 42.66 ? 440 TYR B N 1 ATOM 6661 C CA . TYR B 2 408 ? 78.288 -28.950 15.751 1.00 40.84 ? 440 TYR B CA 1 ATOM 6662 C C . TYR B 2 408 ? 78.608 -30.210 16.483 1.00 41.71 ? 440 TYR B C 1 ATOM 6663 O O . TYR B 2 408 ? 77.748 -30.958 16.830 1.00 39.88 ? 440 TYR B O 1 ATOM 6664 C CB . TYR B 2 408 ? 78.410 -29.248 14.292 1.00 40.65 ? 440 TYR B CB 1 ATOM 6665 C CG . TYR B 2 408 ? 77.369 -30.203 13.821 1.00 40.43 ? 440 TYR B CG 1 ATOM 6666 C CD1 . TYR B 2 408 ? 76.088 -29.802 13.696 1.00 40.45 ? 440 TYR B CD1 1 ATOM 6667 C CD2 . TYR B 2 408 ? 77.669 -31.505 13.499 1.00 38.71 ? 440 TYR B CD2 1 ATOM 6668 C CE1 . TYR B 2 408 ? 75.131 -30.655 13.258 1.00 39.92 ? 440 TYR B CE1 1 ATOM 6669 C CE2 . TYR B 2 408 ? 76.701 -32.363 13.058 1.00 36.87 ? 440 TYR B CE2 1 ATOM 6670 C CZ . TYR B 2 408 ? 75.440 -31.910 12.949 1.00 37.30 ? 440 TYR B CZ 1 ATOM 6671 O OH . TYR B 2 408 ? 74.447 -32.698 12.544 1.00 36.55 ? 440 TYR B OH 1 ATOM 6672 N N . ALA B 2 409 ? 79.877 -30.457 16.688 1.00 45.48 ? 441 ALA B N 1 ATOM 6673 C CA . ALA B 2 409 ? 80.308 -31.651 17.350 1.00 47.34 ? 441 ALA B CA 1 ATOM 6674 C C . ALA B 2 409 ? 80.101 -31.591 18.855 1.00 52.09 ? 441 ALA B C 1 ATOM 6675 O O . ALA B 2 409 ? 79.632 -32.557 19.425 1.00 50.00 ? 441 ALA B O 1 ATOM 6676 C CB . ALA B 2 409 ? 81.739 -31.921 17.006 1.00 46.14 ? 441 ALA B CB 1 ATOM 6677 N N . ASP B 2 410 ? 80.403 -30.471 19.514 1.00 53.52 ? 442 ASP B N 1 ATOM 6678 C CA . ASP B 2 410 ? 80.156 -30.403 20.942 1.00 55.61 ? 442 ASP B CA 1 ATOM 6679 C C . ASP B 2 410 ? 78.698 -30.702 21.174 1.00 57.07 ? 442 ASP B C 1 ATOM 6680 O O . ASP B 2 410 ? 78.314 -30.940 22.298 1.00 65.87 ? 442 ASP B O 1 ATOM 6681 C CB . ASP B 2 410 ? 80.574 -29.094 21.612 1.00 56.07 ? 442 ASP B CB 1 ATOM 6682 C CG . ASP B 2 410 ? 80.265 -29.083 23.118 1.00 56.09 ? 442 ASP B CG 1 ATOM 6683 O OD1 . ASP B 2 410 ? 80.300 -30.145 23.754 1.00 52.74 ? 442 ASP B OD1 1 ATOM 6684 O OD2 . ASP B 2 410 ? 79.974 -28.009 23.667 1.00 53.00 -1 442 ASP B OD2 1 ATOM 6685 N N . CYS B 2 411 ? 77.908 -30.711 20.106 1.00 53.01 ? 443 CYS B N 1 ATOM 6686 C CA . CYS B 2 411 ? 76.488 -31.056 20.148 1.00 54.46 ? 443 CYS B CA 1 ATOM 6687 C C . CYS B 2 411 ? 76.455 -32.605 20.251 1.00 58.78 ? 443 CYS B C 1 ATOM 6688 O O . CYS B 2 411 ? 75.656 -33.281 19.643 1.00 51.53 ? 443 CYS B O 1 ATOM 6689 C CB . CYS B 2 411 ? 75.759 -30.529 18.888 1.00 54.37 ? 443 CYS B CB 1 ATOM 6690 S SG . CYS B 2 411 ? 74.043 -29.916 18.878 1.00 47.76 ? 443 CYS B SG 1 ATOM 6691 N N . LEU B 2 412 ? 77.381 -33.133 21.045 1.00 64.81 ? 444 LEU B N 1 ATOM 6692 C CA . LEU B 2 412 ? 77.557 -34.576 21.395 1.00 64.96 ? 444 LEU B CA 1 ATOM 6693 C C . LEU B 2 412 ? 76.879 -34.502 22.764 1.00 67.01 ? 444 LEU B C 1 ATOM 6694 O O . LEU B 2 412 ? 76.751 -35.533 23.421 1.00 64.45 ? 444 LEU B O 1 ATOM 6695 C CB . LEU B 2 412 ? 78.993 -35.104 21.568 1.00 69.44 ? 444 LEU B CB 1 ATOM 6696 C CG . LEU B 2 412 ? 80.123 -34.329 22.337 1.00 74.49 ? 444 LEU B CG 1 ATOM 6697 C CD1 . LEU B 2 412 ? 79.939 -34.180 23.865 1.00 75.73 ? 444 LEU B CD1 1 ATOM 6698 C CD2 . LEU B 2 412 ? 81.508 -34.920 22.039 1.00 69.06 ? 444 LEU B CD2 1 ATOM 6699 N N . LYS B 2 413 ? 76.476 -33.300 23.207 1.00 68.27 ? 445 LYS B N 1 ATOM 6700 C CA . LYS B 2 413 ? 75.690 -33.105 24.438 1.00 65.99 ? 445 LYS B CA 1 ATOM 6701 C C . LYS B 2 413 ? 74.421 -33.986 24.518 1.00 67.05 ? 445 LYS B C 1 ATOM 6702 O O . LYS B 2 413 ? 73.732 -33.967 25.550 1.00 67.74 ? 445 LYS B O 1 ATOM 6703 C CB . LYS B 2 413 ? 75.318 -31.624 24.589 1.00 63.79 ? 445 LYS B CB 1 ATOM 6704 C CG . LYS B 2 413 ? 75.028 -31.167 26.007 1.00 66.68 ? 445 LYS B CG 1 ATOM 6705 C CD . LYS B 2 413 ? 76.237 -31.389 26.907 1.00 76.12 ? 445 LYS B CD 1 ATOM 6706 C CE . LYS B 2 413 ? 76.560 -30.188 27.779 1.00 81.17 ? 445 LYS B CE 1 ATOM 6707 N NZ . LYS B 2 413 ? 75.381 -29.747 28.565 1.00 86.72 1 445 LYS B NZ 1 ATOM 6708 N N . GLN B 2 414 ? 74.129 -34.732 23.433 1.00 67.15 ? 446 GLN B N 1 ATOM 6709 C CA . GLN B 2 414 ? 73.135 -35.853 23.394 1.00 65.36 ? 446 GLN B CA 1 ATOM 6710 C C . GLN B 2 414 ? 73.739 -37.262 23.058 1.00 65.30 ? 446 GLN B C 1 ATOM 6711 O O . GLN B 2 414 ? 73.668 -38.164 23.891 1.00 58.32 ? 446 GLN B O 1 ATOM 6712 C CB . GLN B 2 414 ? 71.925 -35.537 22.473 1.00 62.40 ? 446 GLN B CB 1 ATOM 6713 C CG . GLN B 2 414 ? 72.144 -34.491 21.384 1.00 63.76 ? 446 GLN B CG 1 ATOM 6714 C CD . GLN B 2 414 ? 72.215 -33.072 21.927 1.00 62.88 ? 446 GLN B CD 1 ATOM 6715 O OE1 . GLN B 2 414 ? 71.346 -32.664 22.676 1.00 56.73 ? 446 GLN B OE1 1 ATOM 6716 N NE2 . GLN B 2 414 ? 73.258 -32.319 21.555 1.00 64.14 ? 446 GLN B NE2 1 ATOM 6717 N N . LEU B 2 415 ? 74.306 -37.463 21.861 1.00 71.06 ? 447 LEU B N 1 ATOM 6718 C CA . LEU B 2 415 ? 75.021 -38.723 21.550 1.00 73.37 ? 447 LEU B CA 1 ATOM 6719 C C . LEU B 2 415 ? 75.987 -38.575 20.354 1.00 71.06 ? 447 LEU B C 1 ATOM 6720 O O . LEU B 2 415 ? 75.632 -38.826 19.204 1.00 63.27 ? 447 LEU B O 1 ATOM 6721 C CB . LEU B 2 415 ? 74.016 -39.883 21.347 1.00 79.83 ? 447 LEU B CB 1 ATOM 6722 C CG . LEU B 2 415 ? 74.422 -41.382 21.393 1.00 85.15 ? 447 LEU B CG 1 ATOM 6723 C CD1 . LEU B 2 415 ? 75.608 -41.691 22.309 1.00 85.95 ? 447 LEU B CD1 1 ATOM 6724 C CD2 . LEU B 2 415 ? 73.219 -42.260 21.775 1.00 80.78 ? 447 LEU B CD2 1 ATOM 6725 N N . PRO C 2 1 ? 42.487 8.133 9.546 1.00 86.44 ? 33 PRO C N 1 ATOM 6726 C CA . PRO C 2 1 ? 43.299 7.984 8.341 1.00 87.36 ? 33 PRO C CA 1 ATOM 6727 C C . PRO C 2 1 ? 42.506 8.246 7.063 1.00 91.31 ? 33 PRO C C 1 ATOM 6728 O O . PRO C 2 1 ? 41.286 8.321 7.105 1.00 88.20 ? 33 PRO C O 1 ATOM 6729 C CB . PRO C 2 1 ? 43.723 6.516 8.375 1.00 83.94 ? 33 PRO C CB 1 ATOM 6730 C CG . PRO C 2 1 ? 43.138 5.905 9.596 1.00 81.74 ? 33 PRO C CG 1 ATOM 6731 C CD . PRO C 2 1 ? 42.155 6.848 10.175 1.00 82.02 ? 33 PRO C CD 1 ATOM 6732 N N . PRO C 2 2 ? 43.249 8.403 5.902 1.00 91.43 ? 34 PRO C N 1 ATOM 6733 C CA . PRO C 2 2 ? 42.465 8.572 4.684 1.00 81.44 ? 34 PRO C CA 1 ATOM 6734 C C . PRO C 2 2 ? 42.544 7.232 4.011 1.00 73.93 ? 34 PRO C C 1 ATOM 6735 O O . PRO C 2 2 ? 43.544 6.562 4.125 1.00 74.92 ? 34 PRO C O 1 ATOM 6736 C CB . PRO C 2 2 ? 43.245 9.589 3.915 1.00 84.01 ? 34 PRO C CB 1 ATOM 6737 C CG . PRO C 2 2 ? 44.629 9.172 4.133 1.00 93.25 ? 34 PRO C CG 1 ATOM 6738 C CD . PRO C 2 2 ? 44.713 8.561 5.501 1.00 93.04 ? 34 PRO C CD 1 ATOM 6739 N N . PRO C 2 3 ? 41.498 6.849 3.315 1.00 66.60 ? 35 PRO C N 1 ATOM 6740 C CA . PRO C 2 3 ? 41.326 5.504 2.737 1.00 62.07 ? 35 PRO C CA 1 ATOM 6741 C C . PRO C 2 3 ? 42.029 5.339 1.376 1.00 60.61 ? 35 PRO C C 1 ATOM 6742 O O . PRO C 2 3 ? 42.373 4.214 1.002 1.00 58.75 ? 35 PRO C O 1 ATOM 6743 C CB . PRO C 2 3 ? 39.812 5.285 2.613 1.00 61.16 ? 35 PRO C CB 1 ATOM 6744 C CG . PRO C 2 3 ? 39.185 6.625 2.782 1.00 63.77 ? 35 PRO C CG 1 ATOM 6745 C CD . PRO C 2 3 ? 40.247 7.649 3.092 1.00 67.19 ? 35 PRO C CD 1 ATOM 6746 N N . ALA C 2 4 ? 42.224 6.432 0.639 1.00 61.07 ? 36 ALA C N 1 ATOM 6747 C CA . ALA C 2 4 ? 43.144 6.436 -0.507 1.00 61.47 ? 36 ALA C CA 1 ATOM 6748 C C . ALA C 2 4 ? 43.954 7.744 -0.518 1.00 62.93 ? 36 ALA C C 1 ATOM 6749 O O . ALA C 2 4 ? 43.430 8.816 -0.178 1.00 66.18 ? 36 ALA C O 1 ATOM 6750 C CB . ALA C 2 4 ? 42.398 6.238 -1.824 1.00 59.06 ? 36 ALA C CB 1 ATOM 6751 N N . ILE C 2 5 ? 45.235 7.625 -0.881 1.00 60.06 ? 37 ILE C N 1 ATOM 6752 C CA . ILE C 2 5 ? 46.180 8.747 -0.963 1.00 58.05 ? 37 ILE C CA 1 ATOM 6753 C C . ILE C 2 5 ? 46.157 9.339 -2.370 1.00 53.62 ? 37 ILE C C 1 ATOM 6754 O O . ILE C 2 5 ? 46.318 8.614 -3.366 1.00 47.92 ? 37 ILE C O 1 ATOM 6755 C CB . ILE C 2 5 ? 47.647 8.294 -0.655 1.00 59.64 ? 37 ILE C CB 1 ATOM 6756 C CG1 . ILE C 2 5 ? 47.773 7.749 0.781 1.00 59.90 ? 37 ILE C CG1 1 ATOM 6757 C CG2 . ILE C 2 5 ? 48.660 9.413 -0.915 1.00 56.37 ? 37 ILE C CG2 1 ATOM 6758 C CD1 . ILE C 2 5 ? 47.268 8.680 1.864 1.00 59.20 ? 37 ILE C CD1 1 ATOM 6759 N N . GLY C 2 6 ? 45.965 10.657 -2.435 1.00 49.60 ? 38 GLY C N 1 ATOM 6760 C CA . GLY C 2 6 ? 46.172 11.416 -3.662 1.00 45.95 ? 38 GLY C CA 1 ATOM 6761 C C . GLY C 2 6 ? 47.628 11.833 -3.790 1.00 44.06 ? 38 GLY C C 1 ATOM 6762 O O . GLY C 2 6 ? 48.265 12.190 -2.791 1.00 42.51 ? 38 GLY C O 1 ATOM 6763 N N . GLN C 2 7 ? 48.152 11.791 -5.019 1.00 41.94 ? 39 GLN C N 1 ATOM 6764 C CA . GLN C 2 7 ? 49.529 12.214 -5.312 1.00 38.62 ? 39 GLN C CA 1 ATOM 6765 C C . GLN C 2 7 ? 49.617 13.042 -6.579 1.00 36.99 ? 39 GLN C C 1 ATOM 6766 O O . GLN C 2 7 ? 48.972 12.756 -7.592 1.00 33.17 ? 39 GLN C O 1 ATOM 6767 C CB . GLN C 2 7 ? 50.471 11.018 -5.458 1.00 38.89 ? 39 GLN C CB 1 ATOM 6768 C CG . GLN C 2 7 ? 50.525 10.116 -4.232 1.00 40.23 ? 39 GLN C CG 1 ATOM 6769 C CD . GLN C 2 7 ? 51.573 9.004 -4.314 1.00 40.29 ? 39 GLN C CD 1 ATOM 6770 O OE1 . GLN C 2 7 ? 51.962 8.546 -5.395 1.00 40.05 ? 39 GLN C OE1 1 ATOM 6771 N NE2 . GLN C 2 7 ? 52.023 8.556 -3.152 1.00 40.89 ? 39 GLN C NE2 1 ATOM 6772 N N . PHE C 2 8 ? 50.438 14.076 -6.499 1.00 37.69 ? 40 PHE C N 1 ATOM 6773 C CA . PHE C 2 8 ? 50.834 14.833 -7.665 1.00 38.06 ? 40 PHE C CA 1 ATOM 6774 C C . PHE C 2 8 ? 52.302 15.242 -7.593 1.00 36.68 ? 40 PHE C C 1 ATOM 6775 O O . PHE C 2 8 ? 52.842 15.453 -6.509 1.00 36.01 ? 40 PHE C O 1 ATOM 6776 C CB . PHE C 2 8 ? 49.911 16.035 -7.867 1.00 38.28 ? 40 PHE C CB 1 ATOM 6777 C CG . PHE C 2 8 ? 49.965 17.046 -6.780 1.00 37.32 ? 40 PHE C CG 1 ATOM 6778 C CD1 . PHE C 2 8 ? 49.237 16.862 -5.631 1.00 38.24 ? 40 PHE C CD1 1 ATOM 6779 C CD2 . PHE C 2 8 ? 50.700 18.210 -6.939 1.00 37.69 ? 40 PHE C CD2 1 ATOM 6780 C CE1 . PHE C 2 8 ? 49.265 17.805 -4.616 1.00 40.92 ? 40 PHE C CE1 1 ATOM 6781 C CE2 . PHE C 2 8 ? 50.719 19.169 -5.952 1.00 40.28 ? 40 PHE C CE2 1 ATOM 6782 C CZ . PHE C 2 8 ? 50.003 18.963 -4.779 1.00 42.56 ? 40 PHE C CZ 1 ATOM 6783 N N . TRP C 2 9 ? 52.935 15.328 -8.768 1.00 37.74 ? 41 TRP C N 1 ATOM 6784 C CA . TRP C 2 9 ? 54.358 15.725 -8.909 1.00 36.83 ? 41 TRP C CA 1 ATOM 6785 C C . TRP C 2 9 ? 54.502 17.241 -8.985 1.00 33.82 ? 41 TRP C C 1 ATOM 6786 O O . TRP C 2 9 ? 53.524 17.959 -9.200 1.00 32.23 ? 41 TRP C O 1 ATOM 6787 C CB . TRP C 2 9 ? 55.008 15.092 -10.160 1.00 38.21 ? 41 TRP C CB 1 ATOM 6788 C CG . TRP C 2 9 ? 55.073 13.599 -10.113 1.00 37.57 ? 41 TRP C CG 1 ATOM 6789 C CD1 . TRP C 2 9 ? 54.197 12.707 -10.689 1.00 38.22 ? 41 TRP C CD1 1 ATOM 6790 C CD2 . TRP C 2 9 ? 56.061 12.824 -9.446 1.00 37.38 ? 41 TRP C CD2 1 ATOM 6791 N NE1 . TRP C 2 9 ? 54.590 11.423 -10.410 1.00 39.71 ? 41 TRP C NE1 1 ATOM 6792 C CE2 . TRP C 2 9 ? 55.729 11.465 -9.644 1.00 39.01 ? 41 TRP C CE2 1 ATOM 6793 C CE3 . TRP C 2 9 ? 57.203 13.143 -8.706 1.00 36.67 ? 41 TRP C CE3 1 ATOM 6794 C CZ2 . TRP C 2 9 ? 56.501 10.428 -9.118 1.00 38.32 ? 41 TRP C CZ2 1 ATOM 6795 C CZ3 . TRP C 2 9 ? 57.972 12.115 -8.192 1.00 37.49 ? 41 TRP C CZ3 1 ATOM 6796 C CH2 . TRP C 2 9 ? 57.616 10.774 -8.395 1.00 38.57 ? 41 TRP C CH2 1 ATOM 6797 N N . HIS C 2 10 ? 55.725 17.711 -8.764 1.00 32.23 ? 42 HIS C N 1 ATOM 6798 C CA . HIS C 2 10 ? 56.055 19.142 -8.843 1.00 32.22 ? 42 HIS C CA 1 ATOM 6799 C C . HIS C 2 10 ? 57.458 19.212 -9.388 1.00 33.13 ? 42 HIS C C 1 ATOM 6800 O O . HIS C 2 10 ? 58.432 18.857 -8.690 1.00 33.11 ? 42 HIS C O 1 ATOM 6801 C CB . HIS C 2 10 ? 55.972 19.873 -7.480 1.00 30.12 ? 42 HIS C CB 1 ATOM 6802 C CG . HIS C 2 10 ? 56.303 21.343 -7.534 1.00 26.61 ? 42 HIS C CG 1 ATOM 6803 N ND1 . HIS C 2 10 ? 56.040 22.195 -6.486 1.00 24.61 ? 42 HIS C ND1 1 ATOM 6804 C CD2 . HIS C 2 10 ? 56.879 22.100 -8.497 1.00 24.95 ? 42 HIS C CD2 1 ATOM 6805 C CE1 . HIS C 2 10 ? 56.437 23.413 -6.802 1.00 24.35 ? 42 HIS C CE1 1 ATOM 6806 N NE2 . HIS C 2 10 ? 56.949 23.382 -8.016 1.00 24.12 ? 42 HIS C NE2 1 ATOM 6807 N N . VAL C 2 11 ? 57.528 19.648 -10.647 1.00 33.32 ? 43 VAL C N 1 ATOM 6808 C CA . VAL C 2 11 ? 58.777 19.914 -11.335 1.00 33.11 ? 43 VAL C CA 1 ATOM 6809 C C . VAL C 2 11 ? 58.876 21.429 -11.514 1.00 34.56 ? 43 VAL C C 1 ATOM 6810 O O . VAL C 2 11 ? 57.873 22.120 -11.661 1.00 37.00 ? 43 VAL C O 1 ATOM 6811 C CB . VAL C 2 11 ? 58.859 19.154 -12.666 1.00 32.37 ? 43 VAL C CB 1 ATOM 6812 C CG1 . VAL C 2 11 ? 58.443 17.693 -12.446 1.00 31.65 ? 43 VAL C CG1 1 ATOM 6813 C CG2 . VAL C 2 11 ? 58.024 19.843 -13.753 1.00 32.56 ? 43 VAL C CG2 1 ATOM 6814 N N . THR C 2 12 ? 60.081 21.956 -11.420 1.00 33.89 ? 44 THR C N 1 ATOM 6815 C CA . THR C 2 12 ? 60.268 23.385 -11.515 1.00 32.92 ? 44 THR C CA 1 ATOM 6816 C C . THR C 2 12 ? 61.663 23.623 -12.042 1.00 34.41 ? 44 THR C C 1 ATOM 6817 O O . THR C 2 12 ? 62.520 22.713 -11.972 1.00 34.17 ? 44 THR C O 1 ATOM 6818 C CB . THR C 2 12 ? 60.108 24.105 -10.159 1.00 32.88 ? 44 THR C CB 1 ATOM 6819 O OG1 . THR C 2 12 ? 60.220 25.531 -10.342 1.00 31.16 ? 44 THR C OG1 1 ATOM 6820 C CG2 . THR C 2 12 ? 61.168 23.639 -9.122 1.00 32.94 ? 44 THR C CG2 1 ATOM 6821 N N . ASP C 2 13 ? 61.847 24.836 -12.588 1.00 33.78 ? 45 ASP C N 1 ATOM 6822 C CA . ASP C 2 13 ? 63.140 25.383 -13.032 1.00 32.42 ? 45 ASP C CA 1 ATOM 6823 C C . ASP C 2 13 ? 63.950 24.343 -13.819 1.00 32.09 ? 45 ASP C C 1 ATOM 6824 O O . ASP C 2 13 ? 65.068 23.919 -13.415 1.00 29.09 ? 45 ASP C O 1 ATOM 6825 C CB . ASP C 2 13 ? 63.894 25.987 -11.821 1.00 30.57 ? 45 ASP C CB 1 ATOM 6826 C CG . ASP C 2 13 ? 63.089 27.089 -11.132 1.00 27.65 ? 45 ASP C CG 1 ATOM 6827 O OD1 . ASP C 2 13 ? 62.447 26.798 -10.099 1.00 26.54 ? 45 ASP C OD1 1 ATOM 6828 O OD2 . ASP C 2 13 ? 63.070 28.224 -11.652 1.00 23.91 -1 45 ASP C OD2 1 ATOM 6829 N N . LEU C 2 14 ? 63.338 23.929 -14.937 1.00 34.10 ? 46 LEU C N 1 ATOM 6830 C CA . LEU C 2 14 ? 63.891 22.863 -15.799 1.00 35.56 ? 46 LEU C CA 1 ATOM 6831 C C . LEU C 2 14 ? 65.197 23.407 -16.436 1.00 35.68 ? 46 LEU C C 1 ATOM 6832 O O . LEU C 2 14 ? 66.228 22.709 -16.415 1.00 35.56 ? 46 LEU C O 1 ATOM 6833 C CB . LEU C 2 14 ? 62.839 22.322 -16.828 1.00 35.12 ? 46 LEU C CB 1 ATOM 6834 C CG . LEU C 2 14 ? 61.538 21.605 -16.349 1.00 33.72 ? 46 LEU C CG 1 ATOM 6835 C CD1 . LEU C 2 14 ? 60.519 21.352 -17.439 1.00 31.90 ? 46 LEU C CD1 1 ATOM 6836 C CD2 . LEU C 2 14 ? 61.854 20.272 -15.725 1.00 33.84 ? 46 LEU C CD2 1 ATOM 6837 N N . HIS C 2 15 ? 65.156 24.676 -16.888 1.00 33.98 ? 47 HIS C N 1 ATOM 6838 C CA . HIS C 2 15 ? 66.327 25.423 -17.391 1.00 33.87 ? 47 HIS C CA 1 ATOM 6839 C C . HIS C 2 15 ? 67.223 24.593 -18.309 1.00 33.90 ? 47 HIS C C 1 ATOM 6840 O O . HIS C 2 15 ? 68.391 24.256 -17.935 1.00 29.94 ? 47 HIS C O 1 ATOM 6841 C CB . HIS C 2 15 ? 67.197 25.973 -16.247 1.00 35.28 ? 47 HIS C CB 1 ATOM 6842 C CG . HIS C 2 15 ? 66.642 27.184 -15.543 1.00 36.01 ? 47 HIS C CG 1 ATOM 6843 N ND1 . HIS C 2 15 ? 66.228 28.314 -16.213 1.00 36.13 ? 47 HIS C ND1 1 ATOM 6844 C CD2 . HIS C 2 15 ? 66.517 27.468 -14.222 1.00 35.74 ? 47 HIS C CD2 1 ATOM 6845 C CE1 . HIS C 2 15 ? 65.829 29.220 -15.341 1.00 35.58 ? 47 HIS C CE1 1 ATOM 6846 N NE2 . HIS C 2 15 ? 65.992 28.731 -14.126 1.00 35.63 ? 47 HIS C NE2 1 ATOM 6847 N N . LEU C 2 16 ? 66.670 24.280 -19.494 1.00 33.68 ? 48 LEU C N 1 ATOM 6848 C CA . LEU C 2 16 ? 67.370 23.487 -20.514 1.00 35.55 ? 48 LEU C CA 1 ATOM 6849 C C . LEU C 2 16 ? 68.385 24.341 -21.243 1.00 36.82 ? 48 LEU C C 1 ATOM 6850 O O . LEU C 2 16 ? 68.046 25.443 -21.700 1.00 37.55 ? 48 LEU C O 1 ATOM 6851 C CB . LEU C 2 16 ? 66.397 22.896 -21.551 1.00 35.36 ? 48 LEU C CB 1 ATOM 6852 C CG . LEU C 2 16 ? 66.988 22.329 -22.861 1.00 34.61 ? 48 LEU C CG 1 ATOM 6853 C CD1 . LEU C 2 16 ? 67.652 20.975 -22.672 1.00 34.85 ? 48 LEU C CD1 1 ATOM 6854 C CD2 . LEU C 2 16 ? 65.918 22.219 -23.926 1.00 35.24 ? 48 LEU C CD2 1 ATOM 6855 N N . ASP C 2 17 ? 69.609 23.816 -21.356 1.00 36.79 ? 49 ASP C N 1 ATOM 6856 C CA . ASP C 2 17 ? 70.659 24.410 -22.177 1.00 41.28 ? 49 ASP C CA 1 ATOM 6857 C C . ASP C 2 17 ? 70.832 23.547 -23.431 1.00 42.23 ? 49 ASP C C 1 ATOM 6858 O O . ASP C 2 17 ? 71.551 22.533 -23.408 1.00 41.41 ? 49 ASP C O 1 ATOM 6859 C CB . ASP C 2 17 ? 71.971 24.484 -21.391 1.00 44.67 ? 49 ASP C CB 1 ATOM 6860 C CG . ASP C 2 17 ? 72.980 25.481 -21.983 1.00 48.68 ? 49 ASP C CG 1 ATOM 6861 O OD1 . ASP C 2 17 ? 72.872 25.882 -23.166 1.00 49.32 ? 49 ASP C OD1 1 ATOM 6862 O OD2 . ASP C 2 17 ? 73.913 25.853 -21.239 1.00 51.37 -1 49 ASP C OD2 1 ATOM 6863 N N . PRO C 2 18 ? 70.173 23.943 -24.538 1.00 42.48 ? 50 PRO C N 1 ATOM 6864 C CA . PRO C 2 18 ? 70.280 23.154 -25.772 1.00 41.59 ? 50 PRO C CA 1 ATOM 6865 C C . PRO C 2 18 ? 71.734 23.010 -26.268 1.00 40.99 ? 50 PRO C C 1 ATOM 6866 O O . PRO C 2 18 ? 72.073 22.000 -26.862 1.00 41.56 ? 50 PRO C O 1 ATOM 6867 C CB . PRO C 2 18 ? 69.425 23.937 -26.769 1.00 42.27 ? 50 PRO C CB 1 ATOM 6868 C CG . PRO C 2 18 ? 68.576 24.854 -25.950 1.00 42.83 ? 50 PRO C CG 1 ATOM 6869 C CD . PRO C 2 18 ? 69.381 25.171 -24.734 1.00 41.86 ? 50 PRO C CD 1 ATOM 6870 N N . THR C 2 19 ? 72.574 24.011 -25.992 1.00 41.08 ? 51 THR C N 1 ATOM 6871 C CA . THR C 2 19 ? 74.018 23.975 -26.258 1.00 37.59 ? 51 THR C CA 1 ATOM 6872 C C . THR C 2 19 ? 74.773 22.802 -25.686 1.00 37.59 ? 51 THR C C 1 ATOM 6873 O O . THR C 2 19 ? 75.744 22.364 -26.278 1.00 38.48 ? 51 THR C O 1 ATOM 6874 C CB . THR C 2 19 ? 74.739 25.156 -25.594 1.00 36.44 ? 51 THR C CB 1 ATOM 6875 O OG1 . THR C 2 19 ? 74.076 26.391 -25.900 1.00 33.91 ? 51 THR C OG1 1 ATOM 6876 C CG2 . THR C 2 19 ? 76.212 25.200 -26.065 1.00 37.97 ? 51 THR C CG2 1 ATOM 6877 N N . TYR C 2 20 ? 74.382 22.342 -24.502 1.00 39.11 ? 52 TYR C N 1 ATOM 6878 C CA . TYR C 2 20 ? 75.238 21.429 -23.725 1.00 40.10 ? 52 TYR C CA 1 ATOM 6879 C C . TYR C 2 20 ? 75.744 20.286 -24.585 1.00 41.79 ? 52 TYR C C 1 ATOM 6880 O O . TYR C 2 20 ? 74.962 19.606 -25.236 1.00 42.69 ? 52 TYR C O 1 ATOM 6881 C CB . TYR C 2 20 ? 74.518 20.852 -22.472 1.00 39.20 ? 52 TYR C CB 1 ATOM 6882 C CG . TYR C 2 20 ? 75.475 20.260 -21.440 1.00 36.81 ? 52 TYR C CG 1 ATOM 6883 C CD1 . TYR C 2 20 ? 75.939 18.945 -21.544 1.00 36.55 ? 52 TYR C CD1 1 ATOM 6884 C CD2 . TYR C 2 20 ? 75.933 21.024 -20.376 1.00 36.22 ? 52 TYR C CD2 1 ATOM 6885 C CE1 . TYR C 2 20 ? 76.828 18.415 -20.616 1.00 35.11 ? 52 TYR C CE1 1 ATOM 6886 C CE2 . TYR C 2 20 ? 76.822 20.500 -19.446 1.00 35.56 ? 52 TYR C CE2 1 ATOM 6887 C CZ . TYR C 2 20 ? 77.267 19.205 -19.576 1.00 35.00 ? 52 TYR C CZ 1 ATOM 6888 O OH . TYR C 2 20 ? 78.149 18.732 -18.650 1.00 34.89 ? 52 TYR C OH 1 ATOM 6889 N N . HIS C 2 21 ? 77.054 20.093 -24.599 1.00 44.94 ? 53 HIS C N 1 ATOM 6890 C CA . HIS C 2 21 ? 77.621 18.843 -25.066 1.00 48.86 ? 53 HIS C CA 1 ATOM 6891 C C . HIS C 2 21 ? 79.042 18.694 -24.514 1.00 48.48 ? 53 HIS C C 1 ATOM 6892 O O . HIS C 2 21 ? 79.775 19.672 -24.403 1.00 49.14 ? 53 HIS C O 1 ATOM 6893 C CB . HIS C 2 21 ? 77.606 18.785 -26.596 1.00 53.79 ? 53 HIS C CB 1 ATOM 6894 C CG . HIS C 2 21 ? 78.548 19.750 -27.246 1.00 60.88 ? 53 HIS C CG 1 ATOM 6895 N ND1 . HIS C 2 21 ? 78.394 21.119 -27.158 1.00 63.17 ? 53 HIS C ND1 1 ATOM 6896 C CD2 . HIS C 2 21 ? 79.663 19.543 -27.988 1.00 65.09 ? 53 HIS C CD2 1 ATOM 6897 C CE1 . HIS C 2 21 ? 79.368 21.712 -27.825 1.00 64.98 ? 53 HIS C CE1 1 ATOM 6898 N NE2 . HIS C 2 21 ? 80.152 20.778 -28.335 1.00 67.93 ? 53 HIS C NE2 1 ATOM 6899 N N . ILE C 2 22 ? 79.419 17.470 -24.157 1.00 48.49 ? 54 ILE C N 1 ATOM 6900 C CA . ILE C 2 22 ? 80.789 17.170 -23.727 1.00 48.16 ? 54 ILE C CA 1 ATOM 6901 C C . ILE C 2 22 ? 81.809 17.504 -24.832 1.00 51.20 ? 54 ILE C C 1 ATOM 6902 O O . ILE C 2 22 ? 81.632 17.184 -26.019 1.00 50.65 ? 54 ILE C O 1 ATOM 6903 C CB . ILE C 2 22 ? 80.934 15.686 -23.286 1.00 47.15 ? 54 ILE C CB 1 ATOM 6904 C CG1 . ILE C 2 22 ? 79.991 15.377 -22.114 1.00 46.95 ? 54 ILE C CG1 1 ATOM 6905 C CG2 . ILE C 2 22 ? 82.378 15.344 -22.918 1.00 46.03 ? 54 ILE C CG2 1 ATOM 6906 C CD1 . ILE C 2 22 ? 80.170 16.293 -20.917 1.00 47.16 ? 54 ILE C CD1 1 ATOM 6907 N N . THR C 2 23 ? 82.878 18.173 -24.426 1.00 55.06 ? 55 THR C N 1 ATOM 6908 C CA . THR C 2 23 ? 83.965 18.512 -25.332 1.00 57.99 ? 55 THR C CA 1 ATOM 6909 C C . THR C 2 23 ? 85.204 18.874 -24.454 1.00 60.00 ? 55 THR C C 1 ATOM 6910 O O . THR C 2 23 ? 85.059 19.139 -23.252 1.00 62.16 ? 55 THR C O 1 ATOM 6911 C CB . THR C 2 23 ? 83.475 19.594 -26.348 1.00 57.21 ? 55 THR C CB 1 ATOM 6912 O OG1 . THR C 2 23 ? 83.882 19.237 -27.675 1.00 58.49 ? 55 THR C OG1 1 ATOM 6913 C CG2 . THR C 2 23 ? 83.931 21.014 -25.985 1.00 56.44 ? 55 THR C CG2 1 ATOM 6914 N N . ASP C 2 24 ? 86.408 18.836 -25.025 1.00 60.76 ? 56 ASP C N 1 ATOM 6915 C CA . ASP C 2 24 ? 87.656 19.045 -24.241 1.00 59.02 ? 56 ASP C CA 1 ATOM 6916 C C . ASP C 2 24 ? 87.950 20.488 -23.825 1.00 55.31 ? 56 ASP C C 1 ATOM 6917 O O . ASP C 2 24 ? 88.696 20.700 -22.874 1.00 57.11 ? 56 ASP C O 1 ATOM 6918 C CB . ASP C 2 24 ? 88.865 18.522 -25.010 1.00 59.88 ? 56 ASP C CB 1 ATOM 6919 C CG . ASP C 2 24 ? 88.754 17.062 -25.311 1.00 61.97 ? 56 ASP C CG 1 ATOM 6920 O OD1 . ASP C 2 24 ? 88.647 16.275 -24.338 1.00 61.51 ? 56 ASP C OD1 1 ATOM 6921 O OD2 . ASP C 2 24 ? 88.755 16.715 -26.515 1.00 63.24 -1 56 ASP C OD2 1 ATOM 6922 N N . ASP C 2 25 ? 87.426 21.457 -24.577 1.00 51.12 ? 57 ASP C N 1 ATOM 6923 C CA . ASP C 2 25 ? 87.446 22.867 -24.197 1.00 49.34 ? 57 ASP C CA 1 ATOM 6924 C C . ASP C 2 25 ? 86.212 23.101 -23.323 1.00 51.18 ? 57 ASP C C 1 ATOM 6925 O O . ASP C 2 25 ? 85.082 23.283 -23.819 1.00 48.88 ? 57 ASP C O 1 ATOM 6926 C CB . ASP C 2 25 ? 87.423 23.763 -25.452 1.00 49.94 ? 57 ASP C CB 1 ATOM 6927 C CG . ASP C 2 25 ? 87.516 25.277 -25.137 1.00 48.94 ? 57 ASP C CG 1 ATOM 6928 O OD1 . ASP C 2 25 ? 87.574 25.693 -23.951 1.00 45.37 ? 57 ASP C OD1 1 ATOM 6929 O OD2 . ASP C 2 25 ? 87.534 26.061 -26.112 1.00 47.31 -1 57 ASP C OD2 1 ATOM 6930 N N . HIS C 2 26 ? 86.445 23.092 -22.011 1.00 51.76 ? 58 HIS C N 1 ATOM 6931 C CA . HIS C 2 26 ? 85.374 23.212 -21.024 1.00 48.80 ? 58 HIS C CA 1 ATOM 6932 C C . HIS C 2 26 ? 84.681 24.591 -21.048 1.00 48.96 ? 58 HIS C C 1 ATOM 6933 O O . HIS C 2 26 ? 83.546 24.722 -20.562 1.00 54.18 ? 58 HIS C O 1 ATOM 6934 C CB . HIS C 2 26 ? 85.896 22.854 -19.617 1.00 47.52 ? 58 HIS C CB 1 ATOM 6935 C CG . HIS C 2 26 ? 86.081 21.378 -19.378 1.00 47.37 ? 58 HIS C CG 1 ATOM 6936 N ND1 . HIS C 2 26 ? 85.556 20.401 -20.208 1.00 46.28 ? 58 HIS C ND1 1 ATOM 6937 C CD2 . HIS C 2 26 ? 86.692 20.716 -18.362 1.00 45.74 ? 58 HIS C CD2 1 ATOM 6938 C CE1 . HIS C 2 26 ? 85.856 19.208 -19.728 1.00 45.83 ? 58 HIS C CE1 1 ATOM 6939 N NE2 . HIS C 2 26 ? 86.541 19.372 -18.607 1.00 47.98 ? 58 HIS C NE2 1 ATOM 6940 N N . THR C 2 27 ? 85.323 25.600 -21.643 1.00 46.23 ? 59 THR C N 1 ATOM 6941 C CA . THR C 2 27 ? 84.667 26.896 -21.852 1.00 46.33 ? 59 THR C CA 1 ATOM 6942 C C . THR C 2 27 ? 83.541 26.820 -22.890 1.00 47.71 ? 59 THR C C 1 ATOM 6943 O O . THR C 2 27 ? 82.657 27.679 -22.886 1.00 44.95 ? 59 THR C O 1 ATOM 6944 C CB . THR C 2 27 ? 85.657 28.005 -22.276 1.00 45.48 ? 59 THR C CB 1 ATOM 6945 O OG1 . THR C 2 27 ? 86.276 27.646 -23.512 1.00 44.60 ? 59 THR C OG1 1 ATOM 6946 C CG2 . THR C 2 27 ? 86.740 28.231 -21.214 1.00 45.25 ? 59 THR C CG2 1 ATOM 6947 N N . LYS C 2 28 ? 83.571 25.798 -23.761 1.00 52.52 ? 60 LYS C N 1 ATOM 6948 C CA . LYS C 2 28 ? 82.556 25.617 -24.840 1.00 57.99 ? 60 LYS C CA 1 ATOM 6949 C C . LYS C 2 28 ? 81.487 24.529 -24.580 1.00 58.46 ? 60 LYS C C 1 ATOM 6950 O O . LYS C 2 28 ? 80.509 24.415 -25.355 1.00 62.39 ? 60 LYS C O 1 ATOM 6951 C CB . LYS C 2 28 ? 83.226 25.331 -26.217 1.00 59.09 ? 60 LYS C CB 1 ATOM 6952 C CG . LYS C 2 28 ? 84.008 26.477 -26.863 1.00 54.66 ? 60 LYS C CG 1 ATOM 6953 C CD . LYS C 2 28 ? 83.199 27.763 -27.017 1.00 52.37 ? 60 LYS C CD 1 ATOM 6954 C CE . LYS C 2 28 ? 84.134 28.930 -27.248 1.00 50.18 ? 60 LYS C CE 1 ATOM 6955 N NZ . LYS C 2 28 ? 84.912 28.676 -28.486 1.00 50.31 1 60 LYS C NZ 1 ATOM 6956 N N . VAL C 2 29 ? 81.661 23.749 -23.511 1.00 54.43 ? 61 VAL C N 1 ATOM 6957 C CA . VAL C 2 29 ? 80.680 22.716 -23.134 1.00 51.13 ? 61 VAL C CA 1 ATOM 6958 C C . VAL C 2 29 ? 79.240 23.267 -23.117 1.00 48.55 ? 61 VAL C C 1 ATOM 6959 O O . VAL C 2 29 ? 78.315 22.632 -23.640 1.00 44.88 ? 61 VAL C O 1 ATOM 6960 C CB . VAL C 2 29 ? 81.013 22.074 -21.766 1.00 49.97 ? 61 VAL C CB 1 ATOM 6961 C CG1 . VAL C 2 29 ? 79.850 21.235 -21.260 1.00 49.77 ? 61 VAL C CG1 1 ATOM 6962 C CG2 . VAL C 2 29 ? 82.262 21.209 -21.859 1.00 49.58 ? 61 VAL C CG2 1 ATOM 6963 N N . CYS C 2 30 ? 79.052 24.450 -22.537 1.00 46.73 ? 62 CYS C N 1 ATOM 6964 C CA . CYS C 2 30 ? 77.709 25.016 -22.455 1.00 46.66 ? 62 CYS C CA 1 ATOM 6965 C C . CYS C 2 30 ? 77.715 26.538 -22.440 1.00 43.32 ? 62 CYS C C 1 ATOM 6966 O O . CYS C 2 30 ? 78.534 27.157 -21.759 1.00 41.37 ? 62 CYS C O 1 ATOM 6967 C CB . CYS C 2 30 ? 76.970 24.480 -21.214 1.00 46.40 ? 62 CYS C CB 1 ATOM 6968 S SG . CYS C 2 30 ? 77.403 25.356 -19.697 1.00 45.65 ? 62 CYS C SG 1 ATOM 6969 N N . ALA C 2 31 ? 76.759 27.110 -23.172 1.00 40.65 ? 63 ALA C N 1 ATOM 6970 C CA . ALA C 2 31 ? 76.610 28.550 -23.305 1.00 41.51 ? 63 ALA C CA 1 ATOM 6971 C C . ALA C 2 31 ? 76.247 29.243 -21.976 1.00 41.71 ? 63 ALA C C 1 ATOM 6972 O O . ALA C 2 31 ? 76.677 30.382 -21.733 1.00 39.70 ? 63 ALA C O 1 ATOM 6973 C CB . ALA C 2 31 ? 75.564 28.870 -24.364 1.00 41.23 ? 63 ALA C CB 1 ATOM 6974 N N . SER C 2 32 ? 75.475 28.567 -21.119 1.00 41.23 ? 64 SER C N 1 ATOM 6975 C CA . SER C 2 32 ? 75.083 29.148 -19.825 1.00 39.28 ? 64 SER C CA 1 ATOM 6976 C C . SER C 2 32 ? 76.277 29.388 -18.892 1.00 38.14 ? 64 SER C C 1 ATOM 6977 O O . SER C 2 32 ? 76.232 30.347 -18.113 1.00 36.51 ? 64 SER C O 1 ATOM 6978 C CB . SER C 2 32 ? 74.016 28.307 -19.124 1.00 38.75 ? 64 SER C CB 1 ATOM 6979 O OG . SER C 2 32 ? 74.458 26.979 -18.961 1.00 39.86 ? 64 SER C OG 1 ATOM 6980 N N . SER C 2 33 ? 77.339 28.564 -18.981 1.00 34.96 ? 65 SER C N 1 ATOM 6981 C CA . SER C 2 33 ? 78.556 28.813 -18.191 1.00 32.65 ? 65 SER C CA 1 ATOM 6982 C C . SER C 2 33 ? 79.128 30.197 -18.524 1.00 33.55 ? 65 SER C C 1 ATOM 6983 O O . SER C 2 33 ? 79.855 30.779 -17.726 1.00 34.65 ? 65 SER C O 1 ATOM 6984 C CB . SER C 2 33 ? 79.626 27.739 -18.400 1.00 31.39 ? 65 SER C CB 1 ATOM 6985 O OG . SER C 2 33 ? 80.656 28.167 -19.287 1.00 31.85 ? 65 SER C OG 1 ATOM 6986 N N . LYS C 2 34 ? 78.797 30.713 -19.706 1.00 33.77 ? 66 LYS C N 1 ATOM 6987 C CA . LYS C 2 34 ? 79.169 32.067 -20.124 1.00 34.66 ? 66 LYS C CA 1 ATOM 6988 C C . LYS C 2 34 ? 80.693 32.204 -20.416 1.00 35.64 ? 66 LYS C C 1 ATOM 6989 O O . LYS C 2 34 ? 81.279 33.283 -20.301 1.00 35.35 ? 66 LYS C O 1 ATOM 6990 C CB . LYS C 2 34 ? 78.633 33.117 -19.124 1.00 33.82 ? 66 LYS C CB 1 ATOM 6991 C CG . LYS C 2 34 ? 77.104 33.205 -19.049 1.00 33.88 ? 66 LYS C CG 1 ATOM 6992 C CD . LYS C 2 34 ? 76.640 33.859 -17.744 1.00 33.67 ? 66 LYS C CD 1 ATOM 6993 C CE . LYS C 2 34 ? 75.129 33.806 -17.535 1.00 33.27 ? 66 LYS C CE 1 ATOM 6994 N NZ . LYS C 2 34 ? 74.726 32.533 -16.909 1.00 33.62 1 66 LYS C NZ 1 ATOM 6995 N N . GLY C 2 35 ? 81.319 31.105 -20.831 1.00 35.43 ? 67 GLY C N 1 ATOM 6996 C CA . GLY C 2 35 ? 82.708 31.143 -21.220 1.00 37.00 ? 67 GLY C CA 1 ATOM 6997 C C . GLY C 2 35 ? 83.637 30.716 -20.105 1.00 38.54 ? 67 GLY C C 1 ATOM 6998 O O . GLY C 2 35 ? 84.841 30.497 -20.335 1.00 38.94 ? 67 GLY C O 1 ATOM 6999 N N . ALA C 2 36 ? 83.097 30.592 -18.896 1.00 39.74 ? 68 ALA C N 1 ATOM 7000 C CA . ALA C 2 36 ? 83.845 29.979 -17.786 1.00 41.04 ? 68 ALA C CA 1 ATOM 7001 C C . ALA C 2 36 ? 84.060 28.465 -18.010 1.00 38.07 ? 68 ALA C C 1 ATOM 7002 O O . ALA C 2 36 ? 83.247 27.795 -18.669 1.00 35.35 ? 68 ALA C O 1 ATOM 7003 C CB . ALA C 2 36 ? 83.131 30.229 -16.453 1.00 41.80 ? 68 ALA C CB 1 ATOM 7004 N N . ASN C 2 37 ? 85.089 27.917 -17.410 1.00 36.31 ? 69 ASN C N 1 ATOM 7005 C CA . ASN C 2 37 ? 85.320 26.510 -17.527 1.00 38.22 ? 69 ASN C CA 1 ATOM 7006 C C . ASN C 2 37 ? 84.302 25.769 -16.686 1.00 38.60 ? 69 ASN C C 1 ATOM 7007 O O . ASN C 2 37 ? 84.092 26.054 -15.537 1.00 35.65 ? 69 ASN C O 1 ATOM 7008 C CB . ASN C 2 37 ? 86.737 26.158 -17.070 1.00 39.34 ? 69 ASN C CB 1 ATOM 7009 C CG . ASN C 2 37 ? 87.672 25.834 -18.215 1.00 39.32 ? 69 ASN C CG 1 ATOM 7010 O OD1 . ASN C 2 37 ? 87.263 25.738 -19.334 1.00 38.58 ? 69 ASN C OD1 1 ATOM 7011 N ND2 . ASN C 2 37 ? 88.935 25.683 -17.923 1.00 41.72 ? 69 ASN C ND2 1 ATOM 7012 N N . ALA C 2 38 ? 83.665 24.789 -17.278 1.00 42.83 ? 70 ALA C N 1 ATOM 7013 C CA . ALA C 2 38 ? 82.698 23.981 -16.602 1.00 47.41 ? 70 ALA C CA 1 ATOM 7014 C C . ALA C 2 38 ? 83.530 23.251 -15.598 1.00 50.46 ? 70 ALA C C 1 ATOM 7015 O O . ALA C 2 38 ? 84.554 22.720 -15.931 1.00 54.44 ? 70 ALA C O 1 ATOM 7016 C CB . ALA C 2 38 ? 82.073 23.019 -17.574 1.00 45.69 ? 70 ALA C CB 1 ATOM 7017 N N . SER C 2 39 ? 83.106 23.224 -14.355 1.00 50.99 ? 71 SER C N 1 ATOM 7018 C CA . SER C 2 39 ? 83.924 22.572 -13.324 1.00 51.21 ? 71 SER C CA 1 ATOM 7019 C C . SER C 2 39 ? 84.396 21.158 -13.689 1.00 49.32 ? 71 SER C C 1 ATOM 7020 O O . SER C 2 39 ? 85.600 20.916 -13.838 1.00 46.46 ? 71 SER C O 1 ATOM 7021 C CB . SER C 2 39 ? 83.165 22.541 -11.994 1.00 51.78 ? 71 SER C CB 1 ATOM 7022 O OG . SER C 2 39 ? 84.075 22.406 -10.925 1.00 51.88 ? 71 SER C OG 1 ATOM 7023 N N . ASN C 2 40 ? 83.438 20.243 -13.835 1.00 48.24 ? 72 ASN C N 1 ATOM 7024 C CA . ASN C 2 40 ? 83.714 18.833 -14.099 1.00 46.08 ? 72 ASN C CA 1 ATOM 7025 C C . ASN C 2 40 ? 82.524 18.149 -14.777 1.00 42.08 ? 72 ASN C C 1 ATOM 7026 O O . ASN C 2 40 ? 81.781 17.382 -14.173 1.00 39.01 ? 72 ASN C O 1 ATOM 7027 C CB . ASN C 2 40 ? 84.062 18.123 -12.805 1.00 48.04 ? 72 ASN C CB 1 ATOM 7028 C CG . ASN C 2 40 ? 84.393 16.673 -13.025 1.00 50.22 ? 72 ASN C CG 1 ATOM 7029 O OD1 . ASN C 2 40 ? 85.025 16.316 -14.021 1.00 51.82 ? 72 ASN C OD1 1 ATOM 7030 N ND2 . ASN C 2 40 ? 83.953 15.821 -12.108 1.00 52.20 ? 72 ASN C ND2 1 ATOM 7031 N N . PRO C 2 41 ? 82.368 18.416 -16.062 1.00 41.06 ? 73 PRO C N 1 ATOM 7032 C CA . PRO C 2 41 ? 81.112 18.151 -16.717 1.00 40.17 ? 73 PRO C CA 1 ATOM 7033 C C . PRO C 2 41 ? 80.928 16.694 -17.034 1.00 40.08 ? 73 PRO C C 1 ATOM 7034 O O . PRO C 2 41 ? 81.895 15.988 -17.287 1.00 40.15 ? 73 PRO C O 1 ATOM 7035 C CB . PRO C 2 41 ? 81.234 18.945 -18.016 1.00 41.33 ? 73 PRO C CB 1 ATOM 7036 C CG . PRO C 2 41 ? 82.710 19.008 -18.297 1.00 41.08 ? 73 PRO C CG 1 ATOM 7037 C CD . PRO C 2 41 ? 83.441 18.772 -17.011 1.00 40.67 ? 73 PRO C CD 1 ATOM 7038 N N . GLY C 2 42 ? 79.676 16.263 -17.034 1.00 41.28 ? 74 GLY C N 1 ATOM 7039 C CA . GLY C 2 42 ? 79.327 14.900 -17.399 1.00 42.01 ? 74 GLY C CA 1 ATOM 7040 C C . GLY C 2 42 ? 78.052 14.851 -18.216 1.00 43.07 ? 74 GLY C C 1 ATOM 7041 O O . GLY C 2 42 ? 77.452 15.893 -18.509 1.00 41.26 ? 74 GLY C O 1 ATOM 7042 N N . PRO C 2 43 ? 77.632 13.634 -18.609 1.00 45.63 ? 75 PRO C N 1 ATOM 7043 C CA . PRO C 2 43 ? 76.443 13.488 -19.459 1.00 45.60 ? 75 PRO C CA 1 ATOM 7044 C C . PRO C 2 43 ? 75.176 14.135 -18.884 1.00 45.84 ? 75 PRO C C 1 ATOM 7045 O O . PRO C 2 43 ? 74.357 14.621 -19.653 1.00 47.33 ? 75 PRO C O 1 ATOM 7046 C CB . PRO C 2 43 ? 76.270 11.964 -19.586 1.00 47.49 ? 75 PRO C CB 1 ATOM 7047 C CG . PRO C 2 43 ? 77.194 11.342 -18.577 1.00 48.00 ? 75 PRO C CG 1 ATOM 7048 C CD . PRO C 2 43 ? 78.281 12.339 -18.317 1.00 46.97 ? 75 PRO C CD 1 ATOM 7049 N N . PHE C 2 44 ? 75.033 14.149 -17.553 1.00 47.24 ? 76 PHE C N 1 ATOM 7050 C CA . PHE C 2 44 ? 73.842 14.706 -16.869 1.00 45.65 ? 76 PHE C CA 1 ATOM 7051 C C . PHE C 2 44 ? 74.014 16.111 -16.292 1.00 41.69 ? 76 PHE C C 1 ATOM 7052 O O . PHE C 2 44 ? 73.135 16.575 -15.561 1.00 39.22 ? 76 PHE C O 1 ATOM 7053 C CB . PHE C 2 44 ? 73.405 13.772 -15.751 1.00 46.45 ? 76 PHE C CB 1 ATOM 7054 C CG . PHE C 2 44 ? 73.282 12.357 -16.191 1.00 48.82 ? 76 PHE C CG 1 ATOM 7055 C CD1 . PHE C 2 44 ? 72.214 11.960 -16.975 1.00 50.89 ? 76 PHE C CD1 1 ATOM 7056 C CD2 . PHE C 2 44 ? 74.250 11.422 -15.858 1.00 50.43 ? 76 PHE C CD2 1 ATOM 7057 C CE1 . PHE C 2 44 ? 72.095 10.644 -17.399 1.00 51.23 ? 76 PHE C CE1 1 ATOM 7058 C CE2 . PHE C 2 44 ? 74.137 10.106 -16.285 1.00 50.90 ? 76 PHE C CE2 1 ATOM 7059 C CZ . PHE C 2 44 ? 73.056 9.714 -17.050 1.00 49.23 ? 76 PHE C CZ 1 ATOM 7060 N N . GLY C 2 45 ? 75.140 16.760 -16.607 1.00 39.00 ? 77 GLY C N 1 ATOM 7061 C CA . GLY C 2 45 ? 75.348 18.181 -16.314 1.00 36.92 ? 77 GLY C CA 1 ATOM 7062 C C . GLY C 2 45 ? 76.656 18.585 -15.632 1.00 35.30 ? 77 GLY C C 1 ATOM 7063 O O . GLY C 2 45 ? 77.513 17.764 -15.281 1.00 33.52 ? 77 GLY C O 1 ATOM 7064 N N . ASP C 2 46 ? 76.815 19.882 -15.469 1.00 33.63 ? 78 ASP C N 1 ATOM 7065 C CA . ASP C 2 46 ? 77.846 20.393 -14.623 1.00 35.46 ? 78 ASP C CA 1 ATOM 7066 C C . ASP C 2 46 ? 77.157 21.451 -13.759 1.00 38.06 ? 78 ASP C C 1 ATOM 7067 O O . ASP C 2 46 ? 76.139 22.015 -14.181 1.00 38.09 ? 78 ASP C O 1 ATOM 7068 C CB . ASP C 2 46 ? 78.967 20.992 -15.470 1.00 35.76 ? 78 ASP C CB 1 ATOM 7069 C CG . ASP C 2 46 ? 80.156 21.477 -14.631 1.00 37.18 ? 78 ASP C CG 1 ATOM 7070 O OD1 . ASP C 2 46 ? 80.752 20.666 -13.902 1.00 36.06 ? 78 ASP C OD1 1 ATOM 7071 O OD2 . ASP C 2 46 ? 80.499 22.685 -14.698 1.00 38.40 -1 78 ASP C OD2 1 ATOM 7072 N N . VAL C 2 47 ? 77.671 21.693 -12.543 1.00 38.62 ? 79 VAL C N 1 ATOM 7073 C CA . VAL C 2 47 ? 77.365 22.949 -11.838 1.00 37.08 ? 79 VAL C CA 1 ATOM 7074 C C . VAL C 2 47 ? 77.950 24.014 -12.778 1.00 36.77 ? 79 VAL C C 1 ATOM 7075 O O . VAL C 2 47 ? 78.816 23.715 -13.593 1.00 39.73 ? 79 VAL C O 1 ATOM 7076 C CB . VAL C 2 47 ? 77.958 23.020 -10.394 1.00 35.65 ? 79 VAL C CB 1 ATOM 7077 C CG1 . VAL C 2 47 ? 77.499 21.840 -9.554 1.00 35.51 ? 79 VAL C CG1 1 ATOM 7078 C CG2 . VAL C 2 47 ? 79.467 23.041 -10.413 1.00 36.66 ? 79 VAL C CG2 1 ATOM 7079 N N . LEU C 2 48 ? 77.480 25.240 -12.745 1.00 35.64 ? 80 LEU C N 1 ATOM 7080 C CA . LEU C 2 48 ? 77.985 26.211 -13.708 1.00 36.76 ? 80 LEU C CA 1 ATOM 7081 C C . LEU C 2 48 ? 77.338 26.061 -15.086 1.00 35.65 ? 80 LEU C C 1 ATOM 7082 O O . LEU C 2 48 ? 77.422 26.975 -15.889 1.00 35.79 ? 80 LEU C O 1 ATOM 7083 C CB . LEU C 2 48 ? 79.510 26.047 -13.923 1.00 37.61 ? 80 LEU C CB 1 ATOM 7084 C CG . LEU C 2 48 ? 80.476 26.993 -13.190 1.00 38.19 ? 80 LEU C CG 1 ATOM 7085 C CD1 . LEU C 2 48 ? 80.068 27.245 -11.759 1.00 38.82 ? 80 LEU C CD1 1 ATOM 7086 C CD2 . LEU C 2 48 ? 81.888 26.431 -13.238 1.00 38.94 ? 80 LEU C CD2 1 ATOM 7087 N N . CYS C 2 49 ? 76.685 24.927 -15.337 1.00 35.44 ? 81 CYS C N 1 ATOM 7088 C CA . CYS C 2 49 ? 76.001 24.647 -16.601 1.00 34.86 ? 81 CYS C CA 1 ATOM 7089 C C . CYS C 2 49 ? 74.569 24.270 -16.331 1.00 32.37 ? 81 CYS C C 1 ATOM 7090 O O . CYS C 2 49 ? 74.283 23.349 -15.595 1.00 30.34 ? 81 CYS C O 1 ATOM 7091 C CB . CYS C 2 49 ? 76.619 23.487 -17.383 1.00 37.39 ? 81 CYS C CB 1 ATOM 7092 S SG . CYS C 2 49 ? 78.071 23.910 -18.377 1.00 42.71 ? 81 CYS C SG 1 ATOM 7093 N N . ASP C 2 50 ? 73.664 24.975 -16.964 1.00 32.29 ? 82 ASP C N 1 ATOM 7094 C CA . ASP C 2 50 ? 72.285 24.601 -16.910 1.00 34.23 ? 82 ASP C CA 1 ATOM 7095 C C . ASP C 2 50 ? 72.071 23.230 -17.490 1.00 33.39 ? 82 ASP C C 1 ATOM 7096 O O . ASP C 2 50 ? 73.006 22.640 -18.014 1.00 30.02 ? 82 ASP C O 1 ATOM 7097 C CB . ASP C 2 50 ? 71.463 25.575 -17.729 1.00 38.11 ? 82 ASP C CB 1 ATOM 7098 C CG . ASP C 2 50 ? 70.834 26.629 -16.878 1.00 41.30 ? 82 ASP C CG 1 ATOM 7099 O OD1 . ASP C 2 50 ? 70.172 26.230 -15.893 1.00 47.34 ? 82 ASP C OD1 1 ATOM 7100 O OD2 . ASP C 2 50 ? 70.990 27.834 -17.184 1.00 41.43 -1 82 ASP C OD2 1 ATOM 7101 N N . SER C 2 51 ? 70.843 22.722 -17.378 1.00 35.58 ? 83 SER C N 1 ATOM 7102 C CA . SER C 2 51 ? 70.559 21.308 -17.649 1.00 38.17 ? 83 SER C CA 1 ATOM 7103 C C . SER C 2 51 ? 70.812 20.853 -19.080 1.00 40.49 ? 83 SER C C 1 ATOM 7104 O O . SER C 2 51 ? 70.272 21.466 -19.997 1.00 42.03 ? 83 SER C O 1 ATOM 7105 C CB . SER C 2 51 ? 69.087 21.033 -17.336 1.00 37.78 ? 83 SER C CB 1 ATOM 7106 O OG . SER C 2 51 ? 68.671 21.701 -16.157 1.00 37.83 ? 83 SER C OG 1 ATOM 7107 N N . PRO C 2 52 ? 71.634 19.790 -19.280 1.00 42.67 ? 84 PRO C N 1 ATOM 7108 C CA . PRO C 2 52 ? 71.587 19.099 -20.579 1.00 41.96 ? 84 PRO C CA 1 ATOM 7109 C C . PRO C 2 52 ? 70.260 18.383 -20.733 1.00 42.28 ? 84 PRO C C 1 ATOM 7110 O O . PRO C 2 52 ? 69.659 17.985 -19.729 1.00 42.18 ? 84 PRO C O 1 ATOM 7111 C CB . PRO C 2 52 ? 72.731 18.074 -20.505 1.00 41.56 ? 84 PRO C CB 1 ATOM 7112 C CG . PRO C 2 52 ? 73.123 17.980 -19.072 1.00 41.88 ? 84 PRO C CG 1 ATOM 7113 C CD . PRO C 2 52 ? 72.702 19.262 -18.403 1.00 43.12 ? 84 PRO C CD 1 ATOM 7114 N N . TYR C 2 53 ? 69.802 18.219 -21.969 1.00 41.91 ? 85 TYR C N 1 ATOM 7115 C CA . TYR C 2 53 ? 68.533 17.535 -22.208 1.00 42.00 ? 85 TYR C CA 1 ATOM 7116 C C . TYR C 2 53 ? 68.437 16.210 -21.467 1.00 40.32 ? 85 TYR C C 1 ATOM 7117 O O . TYR C 2 53 ? 67.395 15.850 -20.921 1.00 39.12 ? 85 TYR C O 1 ATOM 7118 C CB . TYR C 2 53 ? 68.350 17.255 -23.690 1.00 43.95 ? 85 TYR C CB 1 ATOM 7119 C CG . TYR C 2 53 ? 66.981 16.708 -24.006 1.00 45.20 ? 85 TYR C CG 1 ATOM 7120 C CD1 . TYR C 2 53 ? 65.848 17.522 -23.879 1.00 44.80 ? 85 TYR C CD1 1 ATOM 7121 C CD2 . TYR C 2 53 ? 66.808 15.382 -24.422 1.00 43.29 ? 85 TYR C CD2 1 ATOM 7122 C CE1 . TYR C 2 53 ? 64.587 17.038 -24.162 1.00 44.02 ? 85 TYR C CE1 1 ATOM 7123 C CE2 . TYR C 2 53 ? 65.545 14.891 -24.704 1.00 43.86 ? 85 TYR C CE2 1 ATOM 7124 C CZ . TYR C 2 53 ? 64.440 15.730 -24.575 1.00 44.60 ? 85 TYR C CZ 1 ATOM 7125 O OH . TYR C 2 53 ? 63.178 15.278 -24.854 1.00 45.64 ? 85 TYR C OH 1 ATOM 7126 N N . GLN C 2 54 ? 69.546 15.494 -21.453 1.00 40.25 ? 86 GLN C N 1 ATOM 7127 C CA . GLN C 2 54 ? 69.575 14.155 -20.925 1.00 42.19 ? 86 GLN C CA 1 ATOM 7128 C C . GLN C 2 54 ? 69.302 14.074 -19.417 1.00 39.79 ? 86 GLN C C 1 ATOM 7129 O O . GLN C 2 54 ? 68.892 13.020 -18.926 1.00 38.22 ? 86 GLN C O 1 ATOM 7130 C CB . GLN C 2 54 ? 70.916 13.539 -21.254 1.00 45.60 ? 86 GLN C CB 1 ATOM 7131 C CG . GLN C 2 54 ? 70.916 12.031 -21.255 1.00 51.89 ? 86 GLN C CG 1 ATOM 7132 C CD . GLN C 2 54 ? 72.331 11.486 -21.330 1.00 58.91 ? 86 GLN C CD 1 ATOM 7133 O OE1 . GLN C 2 54 ? 72.593 10.322 -21.002 1.00 62.77 ? 86 GLN C OE1 1 ATOM 7134 N NE2 . GLN C 2 54 ? 73.261 12.334 -21.757 1.00 62.05 ? 86 GLN C NE2 1 ATOM 7135 N N . LEU C 2 55 ? 69.535 15.164 -18.684 1.00 38.91 ? 87 LEU C N 1 ATOM 7136 C CA . LEU C 2 55 ? 69.154 15.231 -17.251 1.00 38.73 ? 87 LEU C CA 1 ATOM 7137 C C . LEU C 2 55 ? 67.654 15.497 -17.129 1.00 37.87 ? 87 LEU C C 1 ATOM 7138 O O . LEU C 2 55 ? 66.978 14.858 -16.320 1.00 34.83 ? 87 LEU C O 1 ATOM 7139 C CB . LEU C 2 55 ? 69.962 16.296 -16.468 1.00 38.88 ? 87 LEU C CB 1 ATOM 7140 C CG . LEU C 2 55 ? 69.441 16.818 -15.103 1.00 38.70 ? 87 LEU C CG 1 ATOM 7141 C CD1 . LEU C 2 55 ? 69.881 15.946 -13.955 1.00 38.84 ? 87 LEU C CD1 1 ATOM 7142 C CD2 . LEU C 2 55 ? 69.922 18.223 -14.811 1.00 40.11 ? 87 LEU C CD2 1 ATOM 7143 N N . ILE C 2 56 ? 67.143 16.434 -17.934 1.00 37.80 ? 88 ILE C N 1 ATOM 7144 C CA . ILE C 2 56 ? 65.704 16.721 -17.967 1.00 37.77 ? 88 ILE C CA 1 ATOM 7145 C C . ILE C 2 56 ? 64.942 15.438 -18.265 1.00 40.79 ? 88 ILE C C 1 ATOM 7146 O O . ILE C 2 56 ? 63.899 15.140 -17.667 1.00 38.62 ? 88 ILE C O 1 ATOM 7147 C CB . ILE C 2 56 ? 65.320 17.698 -19.079 1.00 35.41 ? 88 ILE C CB 1 ATOM 7148 C CG1 . ILE C 2 56 ? 66.161 18.971 -19.006 1.00 36.11 ? 88 ILE C CG1 1 ATOM 7149 C CG2 . ILE C 2 56 ? 63.827 17.999 -19.010 1.00 34.30 ? 88 ILE C CG2 1 ATOM 7150 C CD1 . ILE C 2 56 ? 65.983 19.746 -17.732 1.00 37.41 ? 88 ILE C CD1 1 ATOM 7151 N N . LEU C 2 57 ? 65.499 14.687 -19.208 1.00 42.97 ? 89 LEU C N 1 ATOM 7152 C CA . LEU C 2 57 ? 64.879 13.479 -19.687 1.00 46.67 ? 89 LEU C CA 1 ATOM 7153 C C . LEU C 2 57 ? 64.846 12.360 -18.645 1.00 47.64 ? 89 LEU C C 1 ATOM 7154 O O . LEU C 2 57 ? 63.822 11.684 -18.510 1.00 45.39 ? 89 LEU C O 1 ATOM 7155 C CB . LEU C 2 57 ? 65.616 12.999 -20.933 1.00 47.54 ? 89 LEU C CB 1 ATOM 7156 C CG . LEU C 2 57 ? 64.869 11.976 -21.780 1.00 46.62 ? 89 LEU C CG 1 ATOM 7157 C CD1 . LEU C 2 57 ? 63.545 12.548 -22.283 1.00 44.54 ? 89 LEU C CD1 1 ATOM 7158 C CD2 . LEU C 2 57 ? 65.794 11.582 -22.917 1.00 47.40 ? 89 LEU C CD2 1 ATOM 7159 N N . SER C 2 58 ? 65.970 12.171 -17.941 1.00 49.28 ? 90 SER C N 1 ATOM 7160 C CA . SER C 2 58 ? 66.119 11.128 -16.898 1.00 49.47 ? 90 SER C CA 1 ATOM 7161 C C . SER C 2 58 ? 65.331 11.415 -15.618 1.00 50.77 ? 90 SER C C 1 ATOM 7162 O O . SER C 2 58 ? 64.983 10.499 -14.884 1.00 54.26 ? 90 SER C O 1 ATOM 7163 C CB . SER C 2 58 ? 67.584 10.959 -16.508 1.00 48.97 ? 90 SER C CB 1 ATOM 7164 O OG . SER C 2 58 ? 67.978 11.951 -15.571 1.00 47.79 ? 90 SER C OG 1 ATOM 7165 N N . ALA C 2 59 ? 65.106 12.691 -15.335 1.00 50.13 ? 91 ALA C N 1 ATOM 7166 C CA . ALA C 2 59 ? 64.147 13.110 -14.325 1.00 49.86 ? 91 ALA C CA 1 ATOM 7167 C C . ALA C 2 59 ? 62.726 12.615 -14.654 1.00 47.45 ? 91 ALA C C 1 ATOM 7168 O O . ALA C 2 59 ? 62.051 12.033 -13.801 1.00 46.16 ? 91 ALA C O 1 ATOM 7169 C CB . ALA C 2 59 ? 64.151 14.634 -14.223 1.00 52.36 ? 91 ALA C CB 1 ATOM 7170 N N . PHE C 2 60 ? 62.273 12.878 -15.879 1.00 46.19 ? 92 PHE C N 1 ATOM 7171 C CA . PHE C 2 60 ? 60.941 12.461 -16.324 1.00 46.20 ? 92 PHE C CA 1 ATOM 7172 C C . PHE C 2 60 ? 60.838 10.926 -16.524 1.00 48.06 ? 92 PHE C C 1 ATOM 7173 O O . PHE C 2 60 ? 59.726 10.373 -16.491 1.00 47.44 ? 92 PHE C O 1 ATOM 7174 C CB . PHE C 2 60 ? 60.526 13.192 -17.626 1.00 45.39 ? 92 PHE C CB 1 ATOM 7175 C CG . PHE C 2 60 ? 60.058 14.628 -17.436 1.00 45.28 ? 92 PHE C CG 1 ATOM 7176 C CD1 . PHE C 2 60 ? 59.146 14.981 -16.430 1.00 45.67 ? 92 PHE C CD1 1 ATOM 7177 C CD2 . PHE C 2 60 ? 60.479 15.622 -18.311 1.00 45.31 ? 92 PHE C CD2 1 ATOM 7178 C CE1 . PHE C 2 60 ? 58.697 16.293 -16.287 1.00 44.27 ? 92 PHE C CE1 1 ATOM 7179 C CE2 . PHE C 2 60 ? 60.031 16.930 -18.168 1.00 44.93 ? 92 PHE C CE2 1 ATOM 7180 C CZ . PHE C 2 60 ? 59.145 17.267 -17.152 1.00 43.60 ? 92 PHE C CZ 1 ATOM 7181 N N . ASP C 2 61 ? 61.976 10.251 -16.751 1.00 48.80 ? 93 ASP C N 1 ATOM 7182 C CA . ASP C 2 61 ? 61.998 8.788 -16.944 1.00 50.55 ? 93 ASP C CA 1 ATOM 7183 C C . ASP C 2 61 ? 61.893 8.065 -15.603 1.00 53.58 ? 93 ASP C C 1 ATOM 7184 O O . ASP C 2 61 ? 61.261 7.005 -15.513 1.00 61.21 ? 93 ASP C O 1 ATOM 7185 C CB . ASP C 2 61 ? 63.264 8.316 -17.682 1.00 50.21 ? 93 ASP C CB 1 ATOM 7186 C CG . ASP C 2 61 ? 63.251 8.631 -19.191 1.00 50.44 ? 93 ASP C CG 1 ATOM 7187 O OD1 . ASP C 2 61 ? 62.173 8.890 -19.792 1.00 45.18 ? 93 ASP C OD1 1 ATOM 7188 O OD2 . ASP C 2 61 ? 64.362 8.596 -19.778 1.00 52.71 -1 93 ASP C OD2 1 ATOM 7189 N N . PHE C 2 62 ? 62.529 8.626 -14.573 1.00 51.84 ? 94 PHE C N 1 ATOM 7190 C CA . PHE C 2 62 ? 62.313 8.186 -13.187 1.00 48.40 ? 94 PHE C CA 1 ATOM 7191 C C . PHE C 2 62 ? 60.823 8.288 -12.803 1.00 49.22 ? 94 PHE C C 1 ATOM 7192 O O . PHE C 2 62 ? 60.274 7.303 -12.327 1.00 52.80 ? 94 PHE C O 1 ATOM 7193 C CB . PHE C 2 62 ? 63.216 8.964 -12.205 1.00 45.25 ? 94 PHE C CB 1 ATOM 7194 C CG . PHE C 2 62 ? 62.927 8.690 -10.753 1.00 43.14 ? 94 PHE C CG 1 ATOM 7195 C CD1 . PHE C 2 62 ? 63.499 7.602 -10.107 1.00 43.10 ? 94 PHE C CD1 1 ATOM 7196 C CD2 . PHE C 2 62 ? 62.074 9.527 -10.026 1.00 42.63 ? 94 PHE C CD2 1 ATOM 7197 C CE1 . PHE C 2 62 ? 63.223 7.352 -8.766 1.00 43.50 ? 94 PHE C CE1 1 ATOM 7198 C CE2 . PHE C 2 62 ? 61.788 9.284 -8.681 1.00 41.45 ? 94 PHE C CE2 1 ATOM 7199 C CZ . PHE C 2 62 ? 62.365 8.197 -8.051 1.00 42.45 ? 94 PHE C CZ 1 ATOM 7200 N N . ILE C 2 63 ? 60.165 9.437 -13.026 1.00 48.13 ? 95 ILE C N 1 ATOM 7201 C CA . ILE C 2 63 ? 58.717 9.574 -12.713 1.00 49.40 ? 95 ILE C CA 1 ATOM 7202 C C . ILE C 2 63 ? 57.852 8.514 -13.403 1.00 54.93 ? 95 ILE C C 1 ATOM 7203 O O . ILE C 2 63 ? 56.877 8.034 -12.822 1.00 58.69 ? 95 ILE C O 1 ATOM 7204 C CB . ILE C 2 63 ? 58.111 10.936 -13.112 1.00 44.44 ? 95 ILE C CB 1 ATOM 7205 C CG1 . ILE C 2 63 ? 58.693 12.054 -12.255 1.00 43.92 ? 95 ILE C CG1 1 ATOM 7206 C CG2 . ILE C 2 63 ? 56.582 10.905 -12.975 1.00 41.77 ? 95 ILE C CG2 1 ATOM 7207 C CD1 . ILE C 2 63 ? 58.343 13.449 -12.754 1.00 42.55 ? 95 ILE C CD1 1 ATOM 7208 N N . LYS C 2 64 ? 58.187 8.185 -14.647 1.00 58.32 ? 96 LYS C N 1 ATOM 7209 C CA . LYS C 2 64 ? 57.407 7.234 -15.441 1.00 60.20 ? 96 LYS C CA 1 ATOM 7210 C C . LYS C 2 64 ? 57.627 5.818 -14.885 1.00 60.94 ? 96 LYS C C 1 ATOM 7211 O O . LYS C 2 64 ? 56.679 5.091 -14.586 1.00 58.03 ? 96 LYS C O 1 ATOM 7212 C CB . LYS C 2 64 ? 57.827 7.339 -16.909 1.00 60.24 ? 96 LYS C CB 1 ATOM 7213 C CG . LYS C 2 64 ? 56.877 6.733 -17.926 1.00 61.54 ? 96 LYS C CG 1 ATOM 7214 C CD . LYS C 2 64 ? 57.436 7.010 -19.315 1.00 64.53 ? 96 LYS C CD 1 ATOM 7215 C CE . LYS C 2 64 ? 56.579 6.454 -20.440 1.00 65.92 ? 96 LYS C CE 1 ATOM 7216 N NZ . LYS C 2 64 ? 57.198 5.255 -21.070 1.00 66.55 1 96 LYS C NZ 1 ATOM 7217 N N . ASN C 2 65 ? 58.890 5.459 -14.703 1.00 63.59 ? 97 ASN C N 1 ATOM 7218 C CA . ASN C 2 65 ? 59.256 4.177 -14.115 1.00 66.07 ? 97 ASN C CA 1 ATOM 7219 C C . ASN C 2 65 ? 59.269 4.210 -12.584 1.00 69.31 ? 97 ASN C C 1 ATOM 7220 O O . ASN C 2 65 ? 59.825 3.308 -11.951 1.00 75.68 ? 97 ASN C O 1 ATOM 7221 C CB . ASN C 2 65 ? 60.653 3.765 -14.597 1.00 67.24 ? 97 ASN C CB 1 ATOM 7222 C CG . ASN C 2 65 ? 60.687 3.433 -16.068 1.00 69.51 ? 97 ASN C CG 1 ATOM 7223 O OD1 . ASN C 2 65 ? 60.749 2.259 -16.453 1.00 69.45 ? 97 ASN C OD1 1 ATOM 7224 N ND2 . ASN C 2 65 ? 60.644 4.467 -16.907 1.00 71.57 ? 97 ASN C ND2 1 ATOM 7225 N N . SER C 2 66 ? 58.681 5.235 -11.972 1.00 65.88 ? 98 SER C N 1 ATOM 7226 C CA . SER C 2 66 ? 58.860 5.421 -10.537 1.00 61.53 ? 98 SER C CA 1 ATOM 7227 C C . SER C 2 66 ? 58.297 4.226 -9.804 1.00 60.53 ? 98 SER C C 1 ATOM 7228 O O . SER C 2 66 ? 58.985 3.612 -9.000 1.00 67.48 ? 98 SER C O 1 ATOM 7229 C CB . SER C 2 66 ? 58.210 6.722 -10.037 1.00 57.53 ? 98 SER C CB 1 ATOM 7230 O OG . SER C 2 66 ? 56.813 6.599 -9.846 1.00 54.67 ? 98 SER C OG 1 ATOM 7231 N N . GLY C 2 67 ? 57.066 3.869 -10.137 1.00 59.01 ? 99 GLY C N 1 ATOM 7232 C CA . GLY C 2 67 ? 56.290 2.937 -9.338 1.00 60.89 ? 99 GLY C CA 1 ATOM 7233 C C . GLY C 2 67 ? 55.258 3.667 -8.492 1.00 60.15 ? 99 GLY C C 1 ATOM 7234 O O . GLY C 2 67 ? 54.595 3.056 -7.669 1.00 67.86 ? 99 GLY C O 1 ATOM 7235 N N . GLN C 2 68 ? 55.134 4.978 -8.677 1.00 56.79 ? 100 GLN C N 1 ATOM 7236 C CA . GLN C 2 68 ? 54.095 5.761 -8.025 1.00 55.50 ? 100 GLN C CA 1 ATOM 7237 C C . GLN C 2 68 ? 53.053 6.004 -9.084 1.00 54.20 ? 100 GLN C C 1 ATOM 7238 O O . GLN C 2 68 ? 53.270 5.648 -10.232 1.00 56.83 ? 100 GLN C O 1 ATOM 7239 C CB . GLN C 2 68 ? 54.648 7.097 -7.528 1.00 55.56 ? 100 GLN C CB 1 ATOM 7240 C CG . GLN C 2 68 ? 55.877 6.988 -6.626 1.00 54.87 ? 100 GLN C CG 1 ATOM 7241 C CD . GLN C 2 68 ? 55.560 6.746 -5.155 1.00 51.18 ? 100 GLN C CD 1 ATOM 7242 O OE1 . GLN C 2 68 ? 54.397 6.717 -4.735 1.00 42.74 ? 100 GLN C OE1 1 ATOM 7243 N NE2 . GLN C 2 68 ? 56.617 6.585 -4.356 1.00 51.97 ? 100 GLN C NE2 1 ATOM 7244 N N . GLU C 2 69 ? 51.922 6.586 -8.707 1.00 54.11 ? 101 GLU C N 1 ATOM 7245 C CA . GLU C 2 69 ? 50.943 7.054 -9.686 1.00 59.19 ? 101 GLU C CA 1 ATOM 7246 C C . GLU C 2 69 ? 50.291 8.323 -9.149 1.00 55.09 ? 101 GLU C C 1 ATOM 7247 O O . GLU C 2 69 ? 50.006 8.441 -7.957 1.00 53.24 ? 101 GLU C O 1 ATOM 7248 C CB . GLU C 2 69 ? 49.921 5.953 -10.099 1.00 65.98 ? 101 GLU C CB 1 ATOM 7249 C CG . GLU C 2 69 ? 48.646 5.805 -9.265 1.00 74.19 ? 101 GLU C CG 1 ATOM 7250 C CD . GLU C 2 69 ? 48.891 5.315 -7.836 1.00 81.70 ? 101 GLU C CD 1 ATOM 7251 O OE1 . GLU C 2 69 ? 50.016 4.861 -7.520 1.00 85.13 ? 101 GLU C OE1 1 ATOM 7252 O OE2 . GLU C 2 69 ? 47.942 5.376 -7.018 1.00 88.34 -1 101 GLU C OE2 1 ATOM 7253 N N . ALA C 2 70 ? 50.084 9.280 -10.039 1.00 51.61 ? 102 ALA C N 1 ATOM 7254 C CA . ALA C 2 70 ? 49.727 10.623 -9.639 1.00 48.55 ? 102 ALA C CA 1 ATOM 7255 C C . ALA C 2 70 ? 48.478 11.010 -10.365 1.00 45.55 ? 102 ALA C C 1 ATOM 7256 O O . ALA C 2 70 ? 48.291 10.618 -11.502 1.00 44.81 ? 102 ALA C O 1 ATOM 7257 C CB . ALA C 2 70 ? 50.850 11.586 -9.996 1.00 48.39 ? 102 ALA C CB 1 ATOM 7258 N N . SER C 2 71 ? 47.639 11.798 -9.711 1.00 43.83 ? 103 SER C N 1 ATOM 7259 C CA . SER C 2 71 ? 46.454 12.363 -10.350 1.00 44.52 ? 103 SER C CA 1 ATOM 7260 C C . SER C 2 71 ? 46.747 13.579 -11.250 1.00 43.14 ? 103 SER C C 1 ATOM 7261 O O . SER C 2 71 ? 45.962 13.885 -12.151 1.00 40.25 ? 103 SER C O 1 ATOM 7262 C CB . SER C 2 71 ? 45.443 12.747 -9.279 1.00 46.92 ? 103 SER C CB 1 ATOM 7263 O OG . SER C 2 71 ? 44.871 11.583 -8.704 1.00 49.27 ? 103 SER C OG 1 ATOM 7264 N N . PHE C 2 72 ? 47.846 14.284 -10.964 1.00 44.50 ? 104 PHE C N 1 ATOM 7265 C CA . PHE C 2 72 ? 48.352 15.384 -11.808 1.00 43.23 ? 104 PHE C CA 1 ATOM 7266 C C . PHE C 2 72 ? 49.817 15.740 -11.521 1.00 40.67 ? 104 PHE C C 1 ATOM 7267 O O . PHE C 2 72 ? 50.535 15.010 -10.843 1.00 38.38 ? 104 PHE C O 1 ATOM 7268 C CB . PHE C 2 72 ? 47.455 16.628 -11.704 1.00 45.07 ? 104 PHE C CB 1 ATOM 7269 C CG . PHE C 2 72 ? 47.360 17.199 -10.335 1.00 46.36 ? 104 PHE C CG 1 ATOM 7270 C CD1 . PHE C 2 72 ? 46.523 16.614 -9.383 1.00 48.10 ? 104 PHE C CD1 1 ATOM 7271 C CD2 . PHE C 2 72 ? 48.070 18.332 -9.999 1.00 49.68 ? 104 PHE C CD2 1 ATOM 7272 C CE1 . PHE C 2 72 ? 46.415 17.135 -8.102 1.00 49.43 ? 104 PHE C CE1 1 ATOM 7273 C CE2 . PHE C 2 72 ? 47.963 18.867 -8.715 1.00 54.51 ? 104 PHE C CE2 1 ATOM 7274 C CZ . PHE C 2 72 ? 47.135 18.265 -7.766 1.00 52.28 ? 104 PHE C CZ 1 ATOM 7275 N N . MET C 2 73 ? 50.258 16.845 -12.106 1.00 41.68 ? 105 MET C N 1 ATOM 7276 C CA . MET C 2 73 ? 51.624 17.351 -11.992 1.00 39.21 ? 105 MET C CA 1 ATOM 7277 C C . MET C 2 73 ? 51.467 18.851 -11.966 1.00 35.50 ? 105 MET C C 1 ATOM 7278 O O . MET C 2 73 ? 50.496 19.395 -12.446 1.00 32.56 ? 105 MET C O 1 ATOM 7279 C CB . MET C 2 73 ? 52.505 16.895 -13.195 1.00 39.88 ? 105 MET C CB 1 ATOM 7280 C CG . MET C 2 73 ? 53.951 17.425 -13.206 1.00 41.13 ? 105 MET C CG 1 ATOM 7281 S SD . MET C 2 73 ? 55.114 16.813 -14.470 1.00 39.14 ? 105 MET C SD 1 ATOM 7282 C CE . MET C 2 73 ? 55.639 15.321 -13.650 1.00 39.99 ? 105 MET C CE 1 ATOM 7283 N N . ILE C 2 74 ? 52.418 19.513 -11.362 1.00 36.04 ? 106 ILE C N 1 ATOM 7284 C CA A ILE C 2 74 ? 52.454 20.958 -11.261 0.50 38.41 ? 106 ILE C CA 1 ATOM 7285 C CA B ILE C 2 74 ? 52.418 20.959 -11.386 0.50 37.63 ? 106 ILE C CA 1 ATOM 7286 C C . ILE C 2 74 ? 53.797 21.420 -11.824 1.00 41.29 ? 106 ILE C C 1 ATOM 7287 O O . ILE C 2 74 ? 54.841 21.035 -11.262 1.00 41.97 ? 106 ILE C O 1 ATOM 7288 C CB A ILE C 2 74 ? 52.378 21.336 -9.772 0.50 38.49 ? 106 ILE C CB 1 ATOM 7289 C CB B ILE C 2 74 ? 51.948 21.598 -10.063 0.50 36.56 ? 106 ILE C CB 1 ATOM 7290 C CG1 A ILE C 2 74 ? 50.946 21.207 -9.265 0.50 38.41 ? 106 ILE C CG1 1 ATOM 7291 C CG1 B ILE C 2 74 ? 52.765 21.124 -8.854 0.50 36.92 ? 106 ILE C CG1 1 ATOM 7292 C CG2 A ILE C 2 74 ? 52.944 22.716 -9.505 0.50 39.58 ? 106 ILE C CG2 1 ATOM 7293 C CG2 B ILE C 2 74 ? 50.479 21.286 -9.848 0.50 36.11 ? 106 ILE C CG2 1 ATOM 7294 C CD1 A ILE C 2 74 ? 49.903 21.581 -10.285 0.50 38.02 ? 106 ILE C CD1 1 ATOM 7295 C CD1 B ILE C 2 74 ? 52.406 21.854 -7.575 0.50 37.19 ? 106 ILE C CD1 1 ATOM 7296 N N . TRP C 2 75 ? 53.811 22.221 -12.887 1.00 42.87 ? 107 TRP C N 1 ATOM 7297 C CA . TRP C 2 75 ? 55.093 22.606 -13.453 1.00 45.77 ? 107 TRP C CA 1 ATOM 7298 C C . TRP C 2 75 ? 55.190 24.128 -13.440 1.00 48.03 ? 107 TRP C C 1 ATOM 7299 O O . TRP C 2 75 ? 54.452 24.811 -14.121 1.00 54.39 ? 107 TRP C O 1 ATOM 7300 C CB . TRP C 2 75 ? 55.269 21.949 -14.817 1.00 45.54 ? 107 TRP C CB 1 ATOM 7301 C CG . TRP C 2 75 ? 56.432 22.409 -15.610 1.00 48.11 ? 107 TRP C CG 1 ATOM 7302 C CD1 . TRP C 2 75 ? 57.676 22.711 -15.159 1.00 49.24 ? 107 TRP C CD1 1 ATOM 7303 C CD2 . TRP C 2 75 ? 56.460 22.593 -17.030 1.00 51.75 ? 107 TRP C CD2 1 ATOM 7304 N NE1 . TRP C 2 75 ? 58.482 23.099 -16.212 1.00 51.57 ? 107 TRP C NE1 1 ATOM 7305 C CE2 . TRP C 2 75 ? 57.753 23.027 -17.371 1.00 51.29 ? 107 TRP C CE2 1 ATOM 7306 C CE3 . TRP C 2 75 ? 55.506 22.446 -18.047 1.00 51.47 ? 107 TRP C CE3 1 ATOM 7307 C CZ2 . TRP C 2 75 ? 58.118 23.313 -18.685 1.00 51.07 ? 107 TRP C CZ2 1 ATOM 7308 C CZ3 . TRP C 2 75 ? 55.875 22.735 -19.349 1.00 50.57 ? 107 TRP C CZ3 1 ATOM 7309 C CH2 . TRP C 2 75 ? 57.166 23.161 -19.656 1.00 48.86 ? 107 TRP C CH2 1 ATOM 7310 N N . THR C 2 76 ? 56.096 24.646 -12.614 1.00 49.50 ? 108 THR C N 1 ATOM 7311 C CA . THR C 2 76 ? 56.165 26.081 -12.295 1.00 47.78 ? 108 THR C CA 1 ATOM 7312 C C . THR C 2 76 ? 57.225 26.862 -13.113 1.00 45.35 ? 108 THR C C 1 ATOM 7313 O O . THR C 2 76 ? 57.561 28.005 -12.778 1.00 43.96 ? 108 THR C O 1 ATOM 7314 C CB . THR C 2 76 ? 56.394 26.286 -10.774 1.00 48.75 ? 108 THR C CB 1 ATOM 7315 O OG1 . THR C 2 76 ? 57.611 25.650 -10.365 1.00 47.29 ? 108 THR C OG1 1 ATOM 7316 C CG2 . THR C 2 76 ? 55.254 25.684 -9.984 1.00 49.77 ? 108 THR C CG2 1 ATOM 7317 N N . GLY C 2 77 ? 57.764 26.233 -14.159 1.00 41.73 ? 109 GLY C N 1 ATOM 7318 C CA . GLY C 2 77 ? 58.369 26.964 -15.250 1.00 40.19 ? 109 GLY C CA 1 ATOM 7319 C C . GLY C 2 77 ? 59.876 27.074 -15.287 1.00 37.44 ? 109 GLY C C 1 ATOM 7320 O O . GLY C 2 77 ? 60.566 26.098 -14.992 1.00 34.98 ? 109 GLY C O 1 ATOM 7321 N N . ASP C 2 78 ? 60.340 28.269 -15.711 1.00 36.54 ? 110 ASP C N 1 ATOM 7322 C CA . ASP C 2 78 ? 61.753 28.608 -15.995 1.00 35.50 ? 110 ASP C CA 1 ATOM 7323 C C . ASP C 2 78 ? 62.485 27.527 -16.784 1.00 33.18 ? 110 ASP C C 1 ATOM 7324 O O . ASP C 2 78 ? 63.320 26.758 -16.235 1.00 27.82 ? 110 ASP C O 1 ATOM 7325 C CB . ASP C 2 78 ? 62.505 28.948 -14.703 1.00 38.27 ? 110 ASP C CB 1 ATOM 7326 C CG . ASP C 2 78 ? 62.522 30.451 -14.391 1.00 39.34 ? 110 ASP C CG 1 ATOM 7327 O OD1 . ASP C 2 78 ? 62.085 31.276 -15.242 1.00 36.97 ? 110 ASP C OD1 1 ATOM 7328 O OD2 . ASP C 2 78 ? 63.006 30.793 -13.277 1.00 40.62 -1 110 ASP C OD2 1 ATOM 7329 N N . SER C 2 79 ? 62.134 27.488 -18.073 1.00 32.24 ? 111 SER C N 1 ATOM 7330 C CA . SER C 2 79 ? 62.620 26.473 -19.007 1.00 32.30 ? 111 SER C CA 1 ATOM 7331 C C . SER C 2 79 ? 63.780 26.955 -19.893 1.00 34.72 ? 111 SER C C 1 ATOM 7332 O O . SER C 2 79 ? 64.692 26.172 -20.203 1.00 36.27 ? 111 SER C O 1 ATOM 7333 C CB . SER C 2 79 ? 61.460 25.963 -19.838 1.00 29.99 ? 111 SER C CB 1 ATOM 7334 O OG . SER C 2 79 ? 60.388 25.713 -18.973 1.00 28.69 ? 111 SER C OG 1 ATOM 7335 N N . PRO C 2 80 ? 63.770 28.238 -20.300 1.00 36.58 ? 112 PRO C N 1 ATOM 7336 C CA . PRO C 2 80 ? 64.963 28.783 -20.970 1.00 38.26 ? 112 PRO C CA 1 ATOM 7337 C C . PRO C 2 80 ? 66.221 28.907 -20.070 1.00 38.49 ? 112 PRO C C 1 ATOM 7338 O O . PRO C 2 80 ? 66.099 29.340 -18.936 1.00 38.17 ? 112 PRO C O 1 ATOM 7339 C CB . PRO C 2 80 ? 64.489 30.178 -21.389 1.00 37.41 ? 112 PRO C CB 1 ATOM 7340 C CG . PRO C 2 80 ? 63.037 29.981 -21.619 1.00 35.98 ? 112 PRO C CG 1 ATOM 7341 C CD . PRO C 2 80 ? 62.623 29.149 -20.457 1.00 35.91 ? 112 PRO C CD 1 ATOM 7342 N N . PRO C 2 81 ? 67.425 28.594 -20.595 1.00 38.85 ? 113 PRO C N 1 ATOM 7343 C CA . PRO C 2 81 ? 68.653 28.679 -19.783 1.00 39.12 ? 113 PRO C CA 1 ATOM 7344 C C . PRO C 2 81 ? 69.154 30.114 -19.490 1.00 39.60 ? 113 PRO C C 1 ATOM 7345 O O . PRO C 2 81 ? 68.566 31.118 -19.957 1.00 37.78 ? 113 PRO C O 1 ATOM 7346 C CB . PRO C 2 81 ? 69.682 27.955 -20.646 1.00 39.30 ? 113 PRO C CB 1 ATOM 7347 C CG . PRO C 2 81 ? 69.237 28.254 -22.044 1.00 40.34 ? 113 PRO C CG 1 ATOM 7348 C CD . PRO C 2 81 ? 67.743 28.480 -22.030 1.00 38.93 ? 113 PRO C CD 1 ATOM 7349 N N . HIS C 2 82 ? 70.240 30.178 -18.719 1.00 38.96 ? 114 HIS C N 1 ATOM 7350 C CA . HIS C 2 82 ? 70.796 31.434 -18.237 1.00 40.69 ? 114 HIS C CA 1 ATOM 7351 C C . HIS C 2 82 ? 71.923 31.904 -19.132 1.00 41.90 ? 114 HIS C C 1 ATOM 7352 O O . HIS C 2 82 ? 73.099 31.554 -18.948 1.00 39.02 ? 114 HIS C O 1 ATOM 7353 C CB . HIS C 2 82 ? 71.343 31.283 -16.828 1.00 43.55 ? 114 HIS C CB 1 ATOM 7354 C CG . HIS C 2 82 ? 70.307 30.993 -15.794 1.00 44.02 ? 114 HIS C CG 1 ATOM 7355 N ND1 . HIS C 2 82 ? 69.969 29.708 -15.428 1.00 43.65 ? 114 HIS C ND1 1 ATOM 7356 C CD2 . HIS C 2 82 ? 69.563 31.820 -15.021 1.00 44.01 ? 114 HIS C CD2 1 ATOM 7357 C CE1 . HIS C 2 82 ? 69.044 29.756 -14.487 1.00 45.33 ? 114 HIS C CE1 1 ATOM 7358 N NE2 . HIS C 2 82 ? 68.783 31.025 -14.221 1.00 45.12 ? 114 HIS C NE2 1 ATOM 7359 N N . VAL C 2 83 ? 71.532 32.695 -20.119 1.00 44.55 ? 115 VAL C N 1 ATOM 7360 C CA . VAL C 2 83 ? 72.452 33.299 -21.063 1.00 42.84 ? 115 VAL C CA 1 ATOM 7361 C C . VAL C 2 83 ? 71.994 34.755 -21.213 1.00 42.10 ? 115 VAL C C 1 ATOM 7362 O O . VAL C 2 83 ? 70.876 35.112 -20.812 1.00 40.63 ? 115 VAL C O 1 ATOM 7363 C CB . VAL C 2 83 ? 72.492 32.526 -22.416 1.00 41.46 ? 115 VAL C CB 1 ATOM 7364 C CG1 . VAL C 2 83 ? 72.938 31.084 -22.218 1.00 40.84 ? 115 VAL C CG1 1 ATOM 7365 C CG2 . VAL C 2 83 ? 71.140 32.515 -23.086 1.00 42.87 ? 115 VAL C CG2 1 ATOM 7366 N N . PRO C 2 84 ? 72.866 35.610 -21.755 1.00 42.06 ? 116 PRO C N 1 ATOM 7367 C CA . PRO C 2 84 ? 72.498 37.010 -21.819 1.00 41.66 ? 116 PRO C CA 1 ATOM 7368 C C . PRO C 2 84 ? 71.447 37.259 -22.886 1.00 42.31 ? 116 PRO C C 1 ATOM 7369 O O . PRO C 2 84 ? 71.345 36.497 -23.858 1.00 37.71 ? 116 PRO C O 1 ATOM 7370 C CB . PRO C 2 84 ? 73.817 37.708 -22.167 1.00 43.16 ? 116 PRO C CB 1 ATOM 7371 C CG . PRO C 2 84 ? 74.899 36.684 -21.978 1.00 42.61 ? 116 PRO C CG 1 ATOM 7372 C CD . PRO C 2 84 ? 74.238 35.374 -22.235 1.00 42.45 ? 116 PRO C CD 1 ATOM 7373 N N . VAL C 2 85 ? 70.677 38.326 -22.680 1.00 45.71 ? 117 VAL C N 1 ATOM 7374 C CA . VAL C 2 85 ? 69.506 38.662 -23.516 1.00 49.17 ? 117 VAL C CA 1 ATOM 7375 C C . VAL C 2 85 ? 69.781 38.620 -25.028 1.00 49.47 ? 117 VAL C C 1 ATOM 7376 O O . VAL C 2 85 ? 69.067 37.943 -25.768 1.00 45.83 ? 117 VAL C O 1 ATOM 7377 C CB . VAL C 2 85 ? 68.915 40.046 -23.124 1.00 50.80 ? 117 VAL C CB 1 ATOM 7378 C CG1 . VAL C 2 85 ? 67.862 40.509 -24.126 1.00 51.23 ? 117 VAL C CG1 1 ATOM 7379 C CG2 . VAL C 2 85 ? 68.331 39.995 -21.717 1.00 51.96 ? 117 VAL C CG2 1 ATOM 7380 N N . PRO C 2 86 ? 70.809 39.351 -25.494 1.00 53.27 ? 118 PRO C N 1 ATOM 7381 C CA . PRO C 2 86 ? 71.111 39.353 -26.918 1.00 52.74 ? 118 PRO C CA 1 ATOM 7382 C C . PRO C 2 86 ? 71.393 37.978 -27.499 1.00 51.24 ? 118 PRO C C 1 ATOM 7383 O O . PRO C 2 86 ? 71.173 37.775 -28.680 1.00 54.09 ? 118 PRO C O 1 ATOM 7384 C CB . PRO C 2 86 ? 72.362 40.227 -27.016 1.00 53.73 ? 118 PRO C CB 1 ATOM 7385 C CG . PRO C 2 86 ? 72.872 40.370 -25.617 1.00 54.24 ? 118 PRO C CG 1 ATOM 7386 C CD . PRO C 2 86 ? 71.655 40.314 -24.769 1.00 54.92 ? 118 PRO C CD 1 ATOM 7387 N N . GLU C 2 87 ? 71.867 37.038 -26.699 1.00 51.26 ? 119 GLU C N 1 ATOM 7388 C CA . GLU C 2 87 ? 72.117 35.694 -27.223 1.00 53.86 ? 119 GLU C CA 1 ATOM 7389 C C . GLU C 2 87 ? 70.824 34.865 -27.410 1.00 49.16 ? 119 GLU C C 1 ATOM 7390 O O . GLU C 2 87 ? 70.813 33.889 -28.144 1.00 46.05 ? 119 GLU C O 1 ATOM 7391 C CB . GLU C 2 87 ? 73.118 34.958 -26.330 1.00 58.99 ? 119 GLU C CB 1 ATOM 7392 C CG . GLU C 2 87 ? 74.150 34.157 -27.102 1.00 63.28 ? 119 GLU C CG 1 ATOM 7393 C CD . GLU C 2 87 ? 75.145 33.479 -26.186 1.00 69.44 ? 119 GLU C CD 1 ATOM 7394 O OE1 . GLU C 2 87 ? 75.593 32.353 -26.511 1.00 75.47 ? 119 GLU C OE1 1 ATOM 7395 O OE2 . GLU C 2 87 ? 75.473 34.074 -25.137 1.00 70.40 -1 119 GLU C OE2 1 ATOM 7396 N N . LEU C 2 88 ? 69.740 35.264 -26.759 1.00 49.19 ? 120 LEU C N 1 ATOM 7397 C CA . LEU C 2 88 ? 68.453 34.565 -26.875 1.00 49.79 ? 120 LEU C CA 1 ATOM 7398 C C . LEU C 2 88 ? 67.441 35.334 -27.730 1.00 45.20 ? 120 LEU C C 1 ATOM 7399 O O . LEU C 2 88 ? 67.704 36.455 -28.164 1.00 46.37 ? 120 LEU C O 1 ATOM 7400 C CB . LEU C 2 88 ? 67.849 34.354 -25.480 1.00 54.36 ? 120 LEU C CB 1 ATOM 7401 C CG . LEU C 2 88 ? 68.371 33.193 -24.634 1.00 56.11 ? 120 LEU C CG 1 ATOM 7402 C CD1 . LEU C 2 88 ? 67.842 33.340 -23.206 1.00 58.46 ? 120 LEU C CD1 1 ATOM 7403 C CD2 . LEU C 2 88 ? 68.001 31.833 -25.230 1.00 56.79 ? 120 LEU C CD2 1 ATOM 7404 N N . SER C 2 89 ? 66.281 34.732 -27.961 1.00 39.88 ? 121 SER C N 1 ATOM 7405 C CA . SER C 2 89 ? 65.181 35.441 -28.589 1.00 38.62 ? 121 SER C CA 1 ATOM 7406 C C . SER C 2 89 ? 63.838 34.854 -28.172 1.00 39.40 ? 121 SER C C 1 ATOM 7407 O O . SER C 2 89 ? 63.772 33.726 -27.666 1.00 37.62 ? 121 SER C O 1 ATOM 7408 C CB . SER C 2 89 ? 65.327 35.443 -30.126 1.00 38.18 ? 121 SER C CB 1 ATOM 7409 O OG . SER C 2 89 ? 64.879 34.242 -30.748 1.00 35.74 ? 121 SER C OG 1 ATOM 7410 N N . THR C 2 90 ? 62.777 35.637 -28.401 1.00 39.72 ? 122 THR C N 1 ATOM 7411 C CA . THR C 2 90 ? 61.387 35.176 -28.287 1.00 39.70 ? 122 THR C CA 1 ATOM 7412 C C . THR C 2 90 ? 61.137 33.846 -29.030 1.00 43.72 ? 122 THR C C 1 ATOM 7413 O O . THR C 2 90 ? 60.293 33.061 -28.603 1.00 51.44 ? 122 THR C O 1 ATOM 7414 C CB . THR C 2 90 ? 60.376 36.242 -28.793 1.00 37.84 ? 122 THR C CB 1 ATOM 7415 O OG1 . THR C 2 90 ? 60.527 37.460 -28.056 1.00 35.86 ? 122 THR C OG1 1 ATOM 7416 C CG2 . THR C 2 90 ? 58.939 35.762 -28.644 1.00 37.59 ? 122 THR C CG2 1 ATOM 7417 N N . ASP C 2 91 ? 61.846 33.575 -30.126 1.00 46.53 ? 123 ASP C N 1 ATOM 7418 C CA . ASP C 2 91 ? 61.648 32.296 -30.850 1.00 49.26 ? 123 ASP C CA 1 ATOM 7419 C C . ASP C 2 91 ? 62.334 31.098 -30.169 1.00 47.36 ? 123 ASP C C 1 ATOM 7420 O O . ASP C 2 91 ? 61.818 29.973 -30.215 1.00 43.74 ? 123 ASP C O 1 ATOM 7421 C CB . ASP C 2 91 ? 62.045 32.410 -32.341 1.00 50.09 ? 123 ASP C CB 1 ATOM 7422 C CG . ASP C 2 91 ? 60.919 32.989 -33.207 1.00 49.62 ? 123 ASP C CG 1 ATOM 7423 O OD1 . ASP C 2 91 ? 60.220 33.941 -32.777 1.00 52.29 ? 123 ASP C OD1 1 ATOM 7424 O OD2 . ASP C 2 91 ? 60.729 32.485 -34.325 1.00 49.05 -1 123 ASP C OD2 1 ATOM 7425 N N . THR C 2 92 ? 63.476 31.349 -29.532 1.00 47.12 ? 124 THR C N 1 ATOM 7426 C CA . THR C 2 92 ? 64.203 30.299 -28.816 1.00 48.68 ? 124 THR C CA 1 ATOM 7427 C C . THR C 2 92 ? 63.494 29.995 -27.491 1.00 49.10 ? 124 THR C C 1 ATOM 7428 O O . THR C 2 92 ? 63.415 28.832 -27.065 1.00 50.51 ? 124 THR C O 1 ATOM 7429 C CB . THR C 2 92 ? 65.670 30.689 -28.521 1.00 48.14 ? 124 THR C CB 1 ATOM 7430 O OG1 . THR C 2 92 ? 66.126 31.638 -29.487 1.00 49.88 ? 124 THR C OG1 1 ATOM 7431 C CG2 . THR C 2 92 ? 66.580 29.458 -28.542 1.00 47.48 ? 124 THR C CG2 1 ATOM 7432 N N . VAL C 2 93 ? 62.990 31.035 -26.830 1.00 45.61 ? 125 VAL C N 1 ATOM 7433 C CA . VAL C 2 93 ? 62.155 30.826 -25.651 1.00 42.38 ? 125 VAL C CA 1 ATOM 7434 C C . VAL C 2 93 ? 61.045 29.823 -26.024 1.00 42.40 ? 125 VAL C C 1 ATOM 7435 O O . VAL C 2 93 ? 60.938 28.759 -25.396 1.00 43.38 ? 125 VAL C O 1 ATOM 7436 C CB . VAL C 2 93 ? 61.607 32.163 -25.079 1.00 40.23 ? 125 VAL C CB 1 ATOM 7437 C CG1 . VAL C 2 93 ? 60.352 31.967 -24.238 1.00 39.65 ? 125 VAL C CG1 1 ATOM 7438 C CG2 . VAL C 2 93 ? 62.679 32.861 -24.255 1.00 40.61 ? 125 VAL C CG2 1 ATOM 7439 N N . ILE C 2 94 ? 60.281 30.122 -27.080 1.00 39.72 ? 126 ILE C N 1 ATOM 7440 C CA . ILE C 2 94 ? 59.140 29.286 -27.464 1.00 37.67 ? 126 ILE C CA 1 ATOM 7441 C C . ILE C 2 94 ? 59.560 27.875 -27.886 1.00 38.23 ? 126 ILE C C 1 ATOM 7442 O O . ILE C 2 94 ? 58.842 26.917 -27.593 1.00 35.46 ? 126 ILE C O 1 ATOM 7443 C CB . ILE C 2 94 ? 58.281 29.967 -28.544 1.00 36.46 ? 126 ILE C CB 1 ATOM 7444 C CG1 . ILE C 2 94 ? 57.632 31.204 -27.936 1.00 37.72 ? 126 ILE C CG1 1 ATOM 7445 C CG2 . ILE C 2 94 ? 57.194 29.028 -29.064 1.00 35.33 ? 126 ILE C CG2 1 ATOM 7446 C CD1 . ILE C 2 94 ? 56.998 32.137 -28.937 1.00 38.09 ? 126 ILE C CD1 1 ATOM 7447 N N . ASN C 2 95 ? 60.723 27.746 -28.533 1.00 40.85 ? 127 ASN C N 1 ATOM 7448 C CA . ASN C 2 95 ? 61.240 26.426 -28.944 1.00 44.47 ? 127 ASN C CA 1 ATOM 7449 C C . ASN C 2 95 ? 61.567 25.550 -27.750 1.00 45.80 ? 127 ASN C C 1 ATOM 7450 O O . ASN C 2 95 ? 61.218 24.369 -27.724 1.00 46.18 ? 127 ASN C O 1 ATOM 7451 C CB . ASN C 2 95 ? 62.494 26.545 -29.824 1.00 47.01 ? 127 ASN C CB 1 ATOM 7452 C CG . ASN C 2 95 ? 62.203 27.122 -31.206 1.00 49.58 ? 127 ASN C CG 1 ATOM 7453 O OD1 . ASN C 2 95 ? 61.156 26.863 -31.812 1.00 46.92 ? 127 ASN C OD1 1 ATOM 7454 N ND2 . ASN C 2 95 ? 63.145 27.915 -31.714 1.00 53.76 ? 127 ASN C ND2 1 ATOM 7455 N N . VAL C 2 96 ? 62.233 26.144 -26.765 1.00 47.96 ? 128 VAL C N 1 ATOM 7456 C CA . VAL C 2 96 ? 62.523 25.479 -25.483 1.00 49.75 ? 128 VAL C CA 1 ATOM 7457 C C . VAL C 2 96 ? 61.280 25.133 -24.636 1.00 44.44 ? 128 VAL C C 1 ATOM 7458 O O . VAL C 2 96 ? 61.200 24.042 -24.091 1.00 41.57 ? 128 VAL C O 1 ATOM 7459 C CB . VAL C 2 96 ? 63.505 26.325 -24.643 1.00 55.85 ? 128 VAL C CB 1 ATOM 7460 C CG1 . VAL C 2 96 ? 63.567 25.850 -23.194 1.00 57.34 ? 128 VAL C CG1 1 ATOM 7461 C CG2 . VAL C 2 96 ? 64.893 26.288 -25.279 1.00 58.11 ? 128 VAL C CG2 1 ATOM 7462 N N . ILE C 2 97 ? 60.330 26.052 -24.507 1.00 42.18 ? 129 ILE C N 1 ATOM 7463 C CA . ILE C 2 97 ? 59.067 25.730 -23.842 1.00 41.34 ? 129 ILE C CA 1 ATOM 7464 C C . ILE C 2 97 ? 58.333 24.644 -24.636 1.00 43.24 ? 129 ILE C C 1 ATOM 7465 O O . ILE C 2 97 ? 57.793 23.711 -24.044 1.00 42.82 ? 129 ILE C O 1 ATOM 7466 C CB . ILE C 2 97 ? 58.141 26.963 -23.697 1.00 40.23 ? 129 ILE C CB 1 ATOM 7467 C CG1 . ILE C 2 97 ? 58.783 28.032 -22.805 1.00 38.18 ? 129 ILE C CG1 1 ATOM 7468 C CG2 . ILE C 2 97 ? 56.780 26.567 -23.119 1.00 39.41 ? 129 ILE C CG2 1 ATOM 7469 C CD1 . ILE C 2 97 ? 58.079 29.372 -22.873 1.00 36.91 ? 129 ILE C CD1 1 ATOM 7470 N N . THR C 2 98 ? 58.302 24.770 -25.966 1.00 44.47 ? 130 THR C N 1 ATOM 7471 C CA . THR C 2 98 ? 57.621 23.786 -26.822 1.00 47.02 ? 130 THR C CA 1 ATOM 7472 C C . THR C 2 98 ? 58.190 22.364 -26.660 1.00 47.59 ? 130 THR C C 1 ATOM 7473 O O . THR C 2 98 ? 57.420 21.388 -26.627 1.00 45.60 ? 130 THR C O 1 ATOM 7474 C CB . THR C 2 98 ? 57.699 24.192 -28.310 1.00 49.88 ? 130 THR C CB 1 ATOM 7475 O OG1 . THR C 2 98 ? 57.171 25.515 -28.466 1.00 51.84 ? 130 THR C OG1 1 ATOM 7476 C CG2 . THR C 2 98 ? 56.928 23.193 -29.229 1.00 48.70 ? 130 THR C CG2 1 ATOM 7477 N N . ASN C 2 99 ? 59.525 22.258 -26.559 1.00 45.91 ? 131 ASN C N 1 ATOM 7478 C CA . ASN C 2 99 ? 60.215 20.967 -26.348 1.00 45.33 ? 131 ASN C CA 1 ATOM 7479 C C . ASN C 2 99 ? 59.797 20.312 -25.023 1.00 42.45 ? 131 ASN C C 1 ATOM 7480 O O . ASN C 2 99 ? 59.325 19.176 -24.998 1.00 42.06 ? 131 ASN C O 1 ATOM 7481 C CB . ASN C 2 99 ? 61.748 21.137 -26.419 1.00 47.08 ? 131 ASN C CB 1 ATOM 7482 C CG . ASN C 2 99 ? 62.488 19.807 -26.451 1.00 51.86 ? 131 ASN C CG 1 ATOM 7483 O OD1 . ASN C 2 99 ? 62.183 18.907 -25.669 1.00 55.19 ? 131 ASN C OD1 1 ATOM 7484 N ND2 . ASN C 2 99 ? 63.478 19.676 -27.356 1.00 56.50 ? 131 ASN C ND2 1 ATOM 7485 N N . MET C 2 100 ? 59.951 21.044 -23.927 1.00 40.82 ? 132 MET C N 1 ATOM 7486 C CA . MET C 2 100 ? 59.519 20.558 -22.615 1.00 38.87 ? 132 MET C CA 1 ATOM 7487 C C . MET C 2 100 ? 58.054 20.120 -22.697 1.00 38.92 ? 132 MET C C 1 ATOM 7488 O O . MET C 2 100 ? 57.753 18.947 -22.487 1.00 37.70 ? 132 MET C O 1 ATOM 7489 C CB . MET C 2 100 ? 59.713 21.628 -21.530 1.00 36.92 ? 132 MET C CB 1 ATOM 7490 C CG . MET C 2 100 ? 61.158 22.070 -21.305 1.00 36.40 ? 132 MET C CG 1 ATOM 7491 S SD . MET C 2 100 ? 62.303 20.781 -20.739 1.00 36.17 ? 132 MET C SD 1 ATOM 7492 C CE . MET C 2 100 ? 63.175 20.352 -22.233 1.00 37.53 ? 132 MET C CE 1 ATOM 7493 N N . THR C 2 101 ? 57.158 21.047 -23.052 1.00 38.91 ? 133 THR C N 1 ATOM 7494 C CA . THR C 2 101 ? 55.741 20.723 -23.177 1.00 39.15 ? 133 THR C CA 1 ATOM 7495 C C . THR C 2 101 ? 55.551 19.452 -23.994 1.00 40.95 ? 133 THR C C 1 ATOM 7496 O O . THR C 2 101 ? 54.821 18.574 -23.577 1.00 43.89 ? 133 THR C O 1 ATOM 7497 C CB . THR C 2 101 ? 54.901 21.833 -23.838 1.00 39.01 ? 133 THR C CB 1 ATOM 7498 O OG1 . THR C 2 101 ? 55.162 23.103 -23.226 1.00 38.25 ? 133 THR C OG1 1 ATOM 7499 C CG2 . THR C 2 101 ? 53.412 21.500 -23.709 1.00 37.78 ? 133 THR C CG2 1 ATOM 7500 N N . THR C 2 102 ? 56.204 19.338 -25.145 1.00 42.42 ? 134 THR C N 1 ATOM 7501 C CA . THR C 2 102 ? 56.061 18.120 -25.955 1.00 44.89 ? 134 THR C CA 1 ATOM 7502 C C . THR C 2 102 ? 56.614 16.868 -25.256 1.00 44.82 ? 134 THR C C 1 ATOM 7503 O O . THR C 2 102 ? 55.954 15.819 -25.254 1.00 44.19 ? 134 THR C O 1 ATOM 7504 C CB . THR C 2 102 ? 56.748 18.249 -27.323 1.00 45.73 ? 134 THR C CB 1 ATOM 7505 O OG1 . THR C 2 102 ? 56.301 19.444 -27.964 1.00 46.24 ? 134 THR C OG1 1 ATOM 7506 C CG2 . THR C 2 102 ? 56.433 17.034 -28.210 1.00 45.81 ? 134 THR C CG2 1 ATOM 7507 N N . THR C 2 103 ? 57.813 16.994 -24.678 1.00 43.08 ? 135 THR C N 1 ATOM 7508 C CA . THR C 2 103 ? 58.501 15.881 -24.014 1.00 42.52 ? 135 THR C CA 1 ATOM 7509 C C . THR C 2 103 ? 57.671 15.261 -22.883 1.00 44.24 ? 135 THR C C 1 ATOM 7510 O O . THR C 2 103 ? 57.648 14.033 -22.731 1.00 43.04 ? 135 THR C O 1 ATOM 7511 C CB . THR C 2 103 ? 59.858 16.327 -23.435 1.00 41.15 ? 135 THR C CB 1 ATOM 7512 O OG1 . THR C 2 103 ? 60.671 16.888 -24.471 1.00 39.79 ? 135 THR C OG1 1 ATOM 7513 C CG2 . THR C 2 103 ? 60.590 15.149 -22.822 1.00 41.62 ? 135 THR C CG2 1 ATOM 7514 N N . ILE C 2 104 ? 57.009 16.121 -22.100 1.00 46.38 ? 136 ILE C N 1 ATOM 7515 C CA . ILE C 2 104 ? 56.061 15.717 -21.038 1.00 46.62 ? 136 ILE C CA 1 ATOM 7516 C C . ILE C 2 104 ? 54.806 15.056 -21.623 1.00 43.66 ? 136 ILE C C 1 ATOM 7517 O O . ILE C 2 104 ? 54.335 14.037 -21.127 1.00 37.74 ? 136 ILE C O 1 ATOM 7518 C CB . ILE C 2 104 ? 55.627 16.944 -20.180 1.00 48.91 ? 136 ILE C CB 1 ATOM 7519 C CG1 . ILE C 2 104 ? 56.803 17.455 -19.329 1.00 48.43 ? 136 ILE C CG1 1 ATOM 7520 C CG2 . ILE C 2 104 ? 54.416 16.618 -19.291 1.00 49.41 ? 136 ILE C CG2 1 ATOM 7521 C CD1 . ILE C 2 104 ? 56.595 18.864 -18.800 1.00 48.83 ? 136 ILE C CD1 1 ATOM 7522 N N . GLN C 2 105 ? 54.266 15.668 -22.671 1.00 45.66 ? 137 GLN C N 1 ATOM 7523 C CA . GLN C 2 105 ? 53.037 15.189 -23.293 1.00 47.98 ? 137 GLN C CA 1 ATOM 7524 C C . GLN C 2 105 ? 53.252 13.830 -23.940 1.00 48.93 ? 137 GLN C C 1 ATOM 7525 O O . GLN C 2 105 ? 52.328 13.024 -23.991 1.00 49.24 ? 137 GLN C O 1 ATOM 7526 C CB . GLN C 2 105 ? 52.488 16.219 -24.295 1.00 48.50 ? 137 GLN C CB 1 ATOM 7527 C CG . GLN C 2 105 ? 51.792 17.393 -23.603 1.00 50.72 ? 137 GLN C CG 1 ATOM 7528 C CD . GLN C 2 105 ? 51.308 18.499 -24.539 1.00 56.17 ? 137 GLN C CD 1 ATOM 7529 O OE1 . GLN C 2 105 ? 51.282 18.334 -25.764 1.00 66.40 ? 137 GLN C OE1 1 ATOM 7530 N NE2 . GLN C 2 105 ? 50.915 19.639 -23.961 1.00 55.28 ? 137 GLN C NE2 1 ATOM 7531 N N . SER C 2 106 ? 54.475 13.580 -24.405 1.00 50.98 ? 138 SER C N 1 ATOM 7532 C CA . SER C 2 106 ? 54.847 12.288 -24.988 1.00 53.92 ? 138 SER C CA 1 ATOM 7533 C C . SER C 2 106 ? 54.896 11.183 -23.957 1.00 52.97 ? 138 SER C C 1 ATOM 7534 O O . SER C 2 106 ? 54.220 10.166 -24.114 1.00 54.59 ? 138 SER C O 1 ATOM 7535 C CB . SER C 2 106 ? 56.214 12.366 -25.676 1.00 56.79 ? 138 SER C CB 1 ATOM 7536 O OG . SER C 2 106 ? 56.194 13.307 -26.740 1.00 65.05 ? 138 SER C OG 1 ATOM 7537 N N . LEU C 2 107 ? 55.708 11.384 -22.918 1.00 51.86 ? 139 LEU C N 1 ATOM 7538 C CA . LEU C 2 107 ? 55.889 10.387 -21.853 1.00 49.18 ? 139 LEU C CA 1 ATOM 7539 C C . LEU C 2 107 ? 54.678 10.264 -20.949 1.00 46.24 ? 139 LEU C C 1 ATOM 7540 O O . LEU C 2 107 ? 54.440 9.198 -20.404 1.00 43.31 ? 139 LEU C O 1 ATOM 7541 C CB . LEU C 2 107 ? 57.079 10.742 -20.967 1.00 51.11 ? 139 LEU C CB 1 ATOM 7542 C CG . LEU C 2 107 ? 58.502 10.639 -21.514 1.00 53.58 ? 139 LEU C CG 1 ATOM 7543 C CD1 . LEU C 2 107 ? 59.396 11.482 -20.618 1.00 54.49 ? 139 LEU C CD1 1 ATOM 7544 C CD2 . LEU C 2 107 ? 59.008 9.196 -21.594 1.00 53.70 ? 139 LEU C CD2 1 ATOM 7545 N N . PHE C 2 108 ? 53.947 11.364 -20.764 1.00 46.94 ? 140 PHE C N 1 ATOM 7546 C CA . PHE C 2 108 ? 52.773 11.401 -19.875 1.00 49.69 ? 140 PHE C CA 1 ATOM 7547 C C . PHE C 2 108 ? 51.511 11.820 -20.657 1.00 51.74 ? 140 PHE C C 1 ATOM 7548 O O . PHE C 2 108 ? 50.932 12.895 -20.411 1.00 51.96 ? 140 PHE C O 1 ATOM 7549 C CB . PHE C 2 108 ? 53.016 12.320 -18.654 1.00 47.16 ? 140 PHE C CB 1 ATOM 7550 C CG . PHE C 2 108 ? 54.243 11.955 -17.843 1.00 46.24 ? 140 PHE C CG 1 ATOM 7551 C CD1 . PHE C 2 108 ? 54.358 10.708 -17.245 1.00 45.59 ? 140 PHE C CD1 1 ATOM 7552 C CD2 . PHE C 2 108 ? 55.278 12.860 -17.668 1.00 45.34 ? 140 PHE C CD2 1 ATOM 7553 C CE1 . PHE C 2 108 ? 55.485 10.369 -16.505 1.00 44.43 ? 140 PHE C CE1 1 ATOM 7554 C CE2 . PHE C 2 108 ? 56.397 12.523 -16.928 1.00 44.10 ? 140 PHE C CE2 1 ATOM 7555 C CZ . PHE C 2 108 ? 56.502 11.279 -16.348 1.00 43.08 ? 140 PHE C CZ 1 ATOM 7556 N N . PRO C 2 109 ? 51.075 10.958 -21.600 1.00 51.49 ? 141 PRO C N 1 ATOM 7557 C CA . PRO C 2 109 ? 49.928 11.287 -22.464 1.00 51.85 ? 141 PRO C CA 1 ATOM 7558 C C . PRO C 2 109 ? 48.640 11.492 -21.677 1.00 52.35 ? 141 PRO C C 1 ATOM 7559 O O . PRO C 2 109 ? 47.882 12.413 -21.964 1.00 49.08 ? 141 PRO C O 1 ATOM 7560 C CB . PRO C 2 109 ? 49.809 10.062 -23.380 1.00 50.30 ? 141 PRO C CB 1 ATOM 7561 C CG . PRO C 2 109 ? 50.522 8.960 -22.669 1.00 50.09 ? 141 PRO C CG 1 ATOM 7562 C CD . PRO C 2 109 ? 51.603 9.604 -21.865 1.00 49.24 ? 141 PRO C CD 1 ATOM 7563 N N . ASN C 2 110 ? 48.432 10.646 -20.671 1.00 55.80 ? 142 ASN C N 1 ATOM 7564 C CA . ASN C 2 110 ? 47.205 10.649 -19.876 1.00 57.98 ? 142 ASN C CA 1 ATOM 7565 C C . ASN C 2 110 ? 47.272 11.542 -18.642 1.00 55.23 ? 142 ASN C C 1 ATOM 7566 O O . ASN C 2 110 ? 46.335 11.559 -17.843 1.00 56.14 ? 142 ASN C O 1 ATOM 7567 C CB . ASN C 2 110 ? 46.867 9.217 -19.434 1.00 59.69 ? 142 ASN C CB 1 ATOM 7568 C CG . ASN C 2 110 ? 46.753 8.259 -20.603 1.00 59.48 ? 142 ASN C CG 1 ATOM 7569 O OD1 . ASN C 2 110 ? 47.449 7.241 -20.664 1.00 61.69 ? 142 ASN C OD1 1 ATOM 7570 N ND2 . ASN C 2 110 ? 45.884 8.588 -21.545 1.00 57.42 ? 142 ASN C ND2 1 ATOM 7571 N N . LEU C 2 111 ? 48.370 12.273 -18.475 1.00 54.59 ? 143 LEU C N 1 ATOM 7572 C CA . LEU C 2 111 ? 48.562 13.095 -17.278 1.00 52.39 ? 143 LEU C CA 1 ATOM 7573 C C . LEU C 2 111 ? 48.205 14.570 -17.541 1.00 49.15 ? 143 LEU C C 1 ATOM 7574 O O . LEU C 2 111 ? 48.615 15.171 -18.548 1.00 46.30 ? 143 LEU C O 1 ATOM 7575 C CB . LEU C 2 111 ? 50.003 12.956 -16.756 1.00 51.23 ? 143 LEU C CB 1 ATOM 7576 C CG . LEU C 2 111 ? 50.345 13.635 -15.423 1.00 52.28 ? 143 LEU C CG 1 ATOM 7577 C CD1 . LEU C 2 111 ? 49.389 13.222 -14.307 1.00 52.61 ? 143 LEU C CD1 1 ATOM 7578 C CD2 . LEU C 2 111 ? 51.805 13.362 -15.042 1.00 53.04 ? 143 LEU C CD2 1 ATOM 7579 N N . GLN C 2 112 ? 47.409 15.128 -16.633 1.00 45.00 ? 144 GLN C N 1 ATOM 7580 C CA . GLN C 2 112 ? 47.139 16.546 -16.618 1.00 41.47 ? 144 GLN C CA 1 ATOM 7581 C C . GLN C 2 112 ? 48.301 17.207 -15.916 1.00 40.53 ? 144 GLN C C 1 ATOM 7582 O O . GLN C 2 112 ? 48.882 16.635 -14.980 1.00 39.99 ? 144 GLN C O 1 ATOM 7583 C CB . GLN C 2 112 ? 45.857 16.857 -15.863 1.00 41.78 ? 144 GLN C CB 1 ATOM 7584 C CG . GLN C 2 112 ? 45.543 18.339 -15.805 1.00 42.15 ? 144 GLN C CG 1 ATOM 7585 C CD . GLN C 2 112 ? 44.140 18.620 -15.311 1.00 42.94 ? 144 GLN C CD 1 ATOM 7586 O OE1 . GLN C 2 112 ? 43.537 17.815 -14.585 1.00 43.00 ? 144 GLN C OE1 1 ATOM 7587 N NE2 . GLN C 2 112 ? 43.618 19.787 -15.676 1.00 42.93 ? 144 GLN C NE2 1 ATOM 7588 N N . VAL C 2 113 ? 48.635 18.405 -16.390 1.00 37.85 ? 145 VAL C N 1 ATOM 7589 C CA . VAL C 2 113 ? 49.716 19.213 -15.855 1.00 35.39 ? 145 VAL C CA 1 ATOM 7590 C C . VAL C 2 113 ? 49.187 20.647 -15.785 1.00 35.90 ? 145 VAL C C 1 ATOM 7591 O O . VAL C 2 113 ? 48.356 21.040 -16.600 1.00 38.63 ? 145 VAL C O 1 ATOM 7592 C CB . VAL C 2 113 ? 50.966 19.137 -16.756 1.00 33.62 ? 145 VAL C CB 1 ATOM 7593 C CG1 . VAL C 2 113 ? 52.113 19.924 -16.142 1.00 34.80 ? 145 VAL C CG1 1 ATOM 7594 C CG2 . VAL C 2 113 ? 51.392 17.694 -16.990 1.00 32.26 ? 145 VAL C CG2 1 ATOM 7595 N N . PHE C 2 114 ? 49.635 21.423 -14.807 1.00 34.59 ? 146 PHE C N 1 ATOM 7596 C CA . PHE C 2 114 ? 49.205 22.812 -14.701 1.00 34.36 ? 146 PHE C CA 1 ATOM 7597 C C . PHE C 2 114 ? 50.407 23.732 -14.627 1.00 35.11 ? 146 PHE C C 1 ATOM 7598 O O . PHE C 2 114 ? 50.995 23.947 -13.543 1.00 37.78 ? 146 PHE C O 1 ATOM 7599 C CB . PHE C 2 114 ? 48.357 23.025 -13.476 1.00 34.35 ? 146 PHE C CB 1 ATOM 7600 C CG . PHE C 2 114 ? 47.221 22.073 -13.348 1.00 35.47 ? 146 PHE C CG 1 ATOM 7601 C CD1 . PHE C 2 114 ? 47.428 20.797 -12.845 1.00 36.62 ? 146 PHE C CD1 1 ATOM 7602 C CD2 . PHE C 2 114 ? 45.939 22.470 -13.672 1.00 36.14 ? 146 PHE C CD2 1 ATOM 7603 C CE1 . PHE C 2 114 ? 46.383 19.924 -12.682 1.00 36.66 ? 146 PHE C CE1 1 ATOM 7604 C CE2 . PHE C 2 114 ? 44.889 21.608 -13.513 1.00 37.42 ? 146 PHE C CE2 1 ATOM 7605 C CZ . PHE C 2 114 ? 45.112 20.333 -13.019 1.00 38.49 ? 146 PHE C CZ 1 ATOM 7606 N N . PRO C 2 115 ? 50.789 24.283 -15.779 1.00 33.88 ? 147 PRO C N 1 ATOM 7607 C CA . PRO C 2 115 ? 51.939 25.173 -15.791 1.00 32.65 ? 147 PRO C CA 1 ATOM 7608 C C . PRO C 2 115 ? 51.668 26.586 -15.276 1.00 31.94 ? 147 PRO C C 1 ATOM 7609 O O . PRO C 2 115 ? 50.542 27.037 -15.238 1.00 32.51 ? 147 PRO C O 1 ATOM 7610 C CB . PRO C 2 115 ? 52.337 25.202 -17.264 1.00 33.02 ? 147 PRO C CB 1 ATOM 7611 C CG . PRO C 2 115 ? 51.730 23.965 -17.843 1.00 33.82 ? 147 PRO C CG 1 ATOM 7612 C CD . PRO C 2 115 ? 50.416 23.866 -17.139 1.00 33.95 ? 147 PRO C CD 1 ATOM 7613 N N . ALA C 2 116 ? 52.722 27.250 -14.833 1.00 32.85 ? 148 ALA C N 1 ATOM 7614 C CA . ALA C 2 116 ? 52.711 28.678 -14.591 1.00 33.17 ? 148 ALA C CA 1 ATOM 7615 C C . ALA C 2 116 ? 53.950 29.214 -15.247 1.00 34.83 ? 148 ALA C C 1 ATOM 7616 O O . ALA C 2 116 ? 54.927 28.476 -15.461 1.00 34.98 ? 148 ALA C O 1 ATOM 7617 C CB . ALA C 2 116 ? 52.774 28.962 -13.121 1.00 33.60 ? 148 ALA C CB 1 ATOM 7618 N N . LEU C 2 117 ? 53.937 30.502 -15.544 1.00 36.80 ? 149 LEU C N 1 ATOM 7619 C CA . LEU C 2 117 ? 55.089 31.127 -16.204 1.00 39.68 ? 149 LEU C CA 1 ATOM 7620 C C . LEU C 2 117 ? 56.204 31.546 -15.216 1.00 41.71 ? 149 LEU C C 1 ATOM 7621 O O . LEU C 2 117 ? 55.925 32.131 -14.166 1.00 44.37 ? 149 LEU C O 1 ATOM 7622 C CB . LEU C 2 117 ? 54.622 32.323 -17.056 1.00 38.11 ? 149 LEU C CB 1 ATOM 7623 C CG . LEU C 2 117 ? 53.726 31.921 -18.228 1.00 36.83 ? 149 LEU C CG 1 ATOM 7624 C CD1 . LEU C 2 117 ? 53.130 33.165 -18.866 1.00 35.89 ? 149 LEU C CD1 1 ATOM 7625 C CD2 . LEU C 2 117 ? 54.508 31.076 -19.225 1.00 35.81 ? 149 LEU C CD2 1 ATOM 7626 N N . GLY C 2 118 ? 57.455 31.219 -15.553 1.00 42.75 ? 150 GLY C N 1 ATOM 7627 C CA . GLY C 2 118 ? 58.637 31.726 -14.834 1.00 43.36 ? 150 GLY C CA 1 ATOM 7628 C C . GLY C 2 118 ? 59.218 32.923 -15.577 1.00 42.93 ? 150 GLY C C 1 ATOM 7629 O O . GLY C 2 118 ? 58.801 33.206 -16.685 1.00 42.18 ? 150 GLY C O 1 ATOM 7630 N N . ASN C 2 119 ? 60.192 33.619 -14.994 1.00 43.79 ? 151 ASN C N 1 ATOM 7631 C CA . ASN C 2 119 ? 60.698 34.866 -15.605 1.00 44.11 ? 151 ASN C CA 1 ATOM 7632 C C . ASN C 2 119 ? 61.634 34.649 -16.821 1.00 45.38 ? 151 ASN C C 1 ATOM 7633 O O . ASN C 2 119 ? 61.721 35.519 -17.717 1.00 45.06 ? 151 ASN C O 1 ATOM 7634 C CB . ASN C 2 119 ? 61.321 35.796 -14.555 1.00 42.72 ? 151 ASN C CB 1 ATOM 7635 C CG . ASN C 2 119 ? 62.131 35.049 -13.542 1.00 42.50 ? 151 ASN C CG 1 ATOM 7636 O OD1 . ASN C 2 119 ? 61.653 34.075 -12.972 1.00 43.53 ? 151 ASN C OD1 1 ATOM 7637 N ND2 . ASN C 2 119 ? 63.358 35.490 -13.306 1.00 43.18 ? 151 ASN C ND2 1 ATOM 7638 N N . HIS C 2 120 ? 62.297 33.489 -16.875 1.00 42.18 ? 152 HIS C N 1 ATOM 7639 C CA . HIS C 2 120 ? 63.038 33.103 -18.080 1.00 38.40 ? 152 HIS C CA 1 ATOM 7640 C C . HIS C 2 120 ? 62.179 32.545 -19.188 1.00 37.21 ? 152 HIS C C 1 ATOM 7641 O O . HIS C 2 120 ? 62.661 32.356 -20.288 1.00 36.45 ? 152 HIS C O 1 ATOM 7642 C CB . HIS C 2 120 ? 64.124 32.123 -17.732 1.00 36.23 ? 152 HIS C CB 1 ATOM 7643 C CG . HIS C 2 120 ? 65.234 32.760 -16.980 1.00 36.60 ? 152 HIS C CG 1 ATOM 7644 N ND1 . HIS C 2 120 ? 66.474 32.985 -17.532 1.00 37.90 ? 152 HIS C ND1 1 ATOM 7645 C CD2 . HIS C 2 120 ? 65.275 33.283 -15.736 1.00 36.53 ? 152 HIS C CD2 1 ATOM 7646 C CE1 . HIS C 2 120 ? 67.245 33.582 -16.639 1.00 37.73 ? 152 HIS C CE1 1 ATOM 7647 N NE2 . HIS C 2 120 ? 66.542 33.770 -15.539 1.00 35.61 ? 152 HIS C NE2 1 ATOM 7648 N N . ASP C 2 121 ? 60.913 32.279 -18.896 1.00 36.99 ? 153 ASP C N 1 ATOM 7649 C CA . ASP C 2 121 ? 59.963 31.899 -19.916 1.00 38.40 ? 153 ASP C CA 1 ATOM 7650 C C . ASP C 2 121 ? 59.461 33.150 -20.682 1.00 43.68 ? 153 ASP C C 1 ATOM 7651 O O . ASP C 2 121 ? 58.308 33.192 -21.101 1.00 45.65 ? 153 ASP C O 1 ATOM 7652 C CB . ASP C 2 121 ? 58.765 31.153 -19.299 1.00 36.48 ? 153 ASP C CB 1 ATOM 7653 C CG . ASP C 2 121 ? 59.146 29.842 -18.595 1.00 34.76 ? 153 ASP C CG 1 ATOM 7654 O OD1 . ASP C 2 121 ? 60.130 29.134 -18.949 1.00 32.16 ? 153 ASP C OD1 1 ATOM 7655 O OD2 . ASP C 2 121 ? 58.388 29.508 -17.675 1.00 32.61 -1 153 ASP C OD2 1 ATOM 7656 N N . TYR C 2 122 ? 60.306 34.170 -20.854 1.00 48.52 ? 154 TYR C N 1 ATOM 7657 C CA . TYR C 2 122 ? 59.980 35.314 -21.713 1.00 46.79 ? 154 TYR C CA 1 ATOM 7658 C C . TYR C 2 122 ? 61.267 35.880 -22.328 1.00 48.41 ? 154 TYR C C 1 ATOM 7659 O O . TYR C 2 122 ? 62.381 35.580 -21.848 1.00 52.01 ? 154 TYR C O 1 ATOM 7660 C CB . TYR C 2 122 ? 59.233 36.377 -20.912 1.00 45.40 ? 154 TYR C CB 1 ATOM 7661 C CG . TYR C 2 122 ? 58.375 37.293 -21.773 1.00 49.17 ? 154 TYR C CG 1 ATOM 7662 C CD1 . TYR C 2 122 ? 57.116 36.883 -22.239 1.00 49.93 ? 154 TYR C CD1 1 ATOM 7663 C CD2 . TYR C 2 122 ? 58.814 38.575 -22.128 1.00 50.50 ? 154 TYR C CD2 1 ATOM 7664 C CE1 . TYR C 2 122 ? 56.338 37.723 -23.037 1.00 49.11 ? 154 TYR C CE1 1 ATOM 7665 C CE2 . TYR C 2 122 ? 58.035 39.420 -22.920 1.00 48.56 ? 154 TYR C CE2 1 ATOM 7666 C CZ . TYR C 2 122 ? 56.805 38.991 -23.371 1.00 47.50 ? 154 TYR C CZ 1 ATOM 7667 O OH . TYR C 2 122 ? 56.051 39.835 -24.139 1.00 42.56 ? 154 TYR C OH 1 ATOM 7668 N N . TRP C 2 123 ? 61.116 36.652 -23.408 1.00 47.46 ? 155 TRP C N 1 ATOM 7669 C CA . TRP C 2 123 ? 62.232 37.423 -23.995 1.00 48.86 ? 155 TRP C CA 1 ATOM 7670 C C . TRP C 2 123 ? 61.866 38.914 -24.195 1.00 48.16 ? 155 TRP C C 1 ATOM 7671 O O . TRP C 2 123 ? 60.932 39.242 -24.913 1.00 50.84 ? 155 TRP C O 1 ATOM 7672 C CB . TRP C 2 123 ? 62.729 36.822 -25.326 1.00 48.66 ? 155 TRP C CB 1 ATOM 7673 C CG . TRP C 2 123 ? 64.080 37.363 -25.715 1.00 50.20 ? 155 TRP C CG 1 ATOM 7674 C CD1 . TRP C 2 123 ? 65.300 36.832 -25.396 1.00 51.21 ? 155 TRP C CD1 1 ATOM 7675 C CD2 . TRP C 2 123 ? 64.349 38.571 -26.452 1.00 52.75 ? 155 TRP C CD2 1 ATOM 7676 N NE1 . TRP C 2 123 ? 66.310 37.626 -25.893 1.00 53.15 ? 155 TRP C NE1 1 ATOM 7677 C CE2 . TRP C 2 123 ? 65.758 38.698 -26.548 1.00 52.79 ? 155 TRP C CE2 1 ATOM 7678 C CE3 . TRP C 2 123 ? 63.538 39.554 -27.044 1.00 51.41 ? 155 TRP C CE3 1 ATOM 7679 C CZ2 . TRP C 2 123 ? 66.377 39.768 -27.227 1.00 51.02 ? 155 TRP C CZ2 1 ATOM 7680 C CZ3 . TRP C 2 123 ? 64.153 40.616 -27.708 1.00 51.37 ? 155 TRP C CZ3 1 ATOM 7681 C CH2 . TRP C 2 123 ? 65.562 40.710 -27.797 1.00 51.00 ? 155 TRP C CH2 1 ATOM 7682 N N . PRO C 2 124 ? 62.610 39.829 -23.588 1.00 48.85 ? 156 PRO C N 1 ATOM 7683 C CA . PRO C 2 124 ? 63.811 39.540 -22.755 1.00 49.27 ? 156 PRO C CA 1 ATOM 7684 C C . PRO C 2 124 ? 63.423 38.968 -21.369 1.00 45.76 ? 156 PRO C C 1 ATOM 7685 O O . PRO C 2 124 ? 62.283 39.137 -20.962 1.00 46.82 ? 156 PRO C O 1 ATOM 7686 C CB . PRO C 2 124 ? 64.491 40.916 -22.631 1.00 49.80 ? 156 PRO C CB 1 ATOM 7687 C CG . PRO C 2 124 ? 63.493 41.935 -23.139 1.00 49.41 ? 156 PRO C CG 1 ATOM 7688 C CD . PRO C 2 124 ? 62.505 41.237 -24.018 1.00 48.10 ? 156 PRO C CD 1 ATOM 7689 N N . GLN C 2 125 ? 64.323 38.309 -20.641 1.00 41.53 ? 157 GLN C N 1 ATOM 7690 C CA . GLN C 2 125 ? 63.894 37.722 -19.366 1.00 41.78 ? 157 GLN C CA 1 ATOM 7691 C C . GLN C 2 125 ? 63.250 38.761 -18.429 1.00 38.94 ? 157 GLN C C 1 ATOM 7692 O O . GLN C 2 125 ? 63.514 39.955 -18.537 1.00 34.46 ? 157 GLN C O 1 ATOM 7693 C CB . GLN C 2 125 ? 64.993 36.876 -18.665 1.00 44.07 ? 157 GLN C CB 1 ATOM 7694 C CG . GLN C 2 125 ? 66.242 37.594 -18.160 1.00 44.52 ? 157 GLN C CG 1 ATOM 7695 C CD . GLN C 2 125 ? 67.490 36.704 -18.253 1.00 48.31 ? 157 GLN C CD 1 ATOM 7696 O OE1 . GLN C 2 125 ? 67.817 36.148 -19.319 1.00 51.09 ? 157 GLN C OE1 1 ATOM 7697 N NE2 . GLN C 2 125 ? 68.193 36.564 -17.147 1.00 49.55 ? 157 GLN C NE2 1 ATOM 7698 N N . ASP C 2 126 ? 62.340 38.276 -17.578 1.00 38.58 ? 158 ASP C N 1 ATOM 7699 C CA . ASP C 2 126 ? 61.616 39.060 -16.566 1.00 38.95 ? 158 ASP C CA 1 ATOM 7700 C C . ASP C 2 126 ? 60.676 40.169 -17.049 1.00 41.36 ? 158 ASP C C 1 ATOM 7701 O O . ASP C 2 126 ? 60.064 40.842 -16.227 1.00 39.85 ? 158 ASP C O 1 ATOM 7702 C CB . ASP C 2 126 ? 62.583 39.758 -15.627 1.00 38.50 ? 158 ASP C CB 1 ATOM 7703 C CG . ASP C 2 126 ? 63.641 38.856 -15.129 1.00 38.24 ? 158 ASP C CG 1 ATOM 7704 O OD1 . ASP C 2 126 ? 63.801 37.752 -15.692 1.00 36.41 ? 158 ASP C OD1 1 ATOM 7705 O OD2 . ASP C 2 126 ? 64.327 39.271 -14.181 1.00 40.07 -1 158 ASP C OD2 1 ATOM 7706 N N . GLN C 2 127 ? 60.540 40.350 -18.356 1.00 46.65 ? 159 GLN C N 1 ATOM 7707 C CA . GLN C 2 127 ? 59.728 41.437 -18.908 1.00 51.55 ? 159 GLN C CA 1 ATOM 7708 C C . GLN C 2 127 ? 58.367 40.867 -19.336 1.00 53.70 ? 159 GLN C C 1 ATOM 7709 O O . GLN C 2 127 ? 57.929 41.061 -20.472 1.00 55.78 ? 159 GLN C O 1 ATOM 7710 C CB . GLN C 2 127 ? 60.408 42.101 -20.111 1.00 53.38 ? 159 GLN C CB 1 ATOM 7711 C CG . GLN C 2 127 ? 61.827 42.595 -19.857 1.00 54.29 ? 159 GLN C CG 1 ATOM 7712 C CD . GLN C 2 127 ? 61.898 43.701 -18.820 1.00 54.25 ? 159 GLN C CD 1 ATOM 7713 O OE1 . GLN C 2 127 ? 61.463 44.839 -19.065 1.00 53.72 ? 159 GLN C OE1 1 ATOM 7714 N NE2 . GLN C 2 127 ? 62.480 43.380 -17.661 1.00 50.28 ? 159 GLN C NE2 1 ATOM 7715 N N . LEU C 2 128 ? 57.704 40.162 -18.428 1.00 54.53 ? 160 LEU C N 1 ATOM 7716 C CA . LEU C 2 128 ? 56.394 39.595 -18.712 1.00 56.26 ? 160 LEU C CA 1 ATOM 7717 C C . LEU C 2 128 ? 55.349 40.731 -18.633 1.00 60.83 ? 160 LEU C C 1 ATOM 7718 O O . LEU C 2 128 ? 55.309 41.462 -17.631 1.00 65.87 ? 160 LEU C O 1 ATOM 7719 C CB . LEU C 2 128 ? 56.089 38.432 -17.745 1.00 54.33 ? 160 LEU C CB 1 ATOM 7720 C CG . LEU C 2 128 ? 56.738 37.072 -18.107 1.00 52.81 ? 160 LEU C CG 1 ATOM 7721 C CD1 . LEU C 2 128 ? 58.193 36.996 -17.653 1.00 52.43 ? 160 LEU C CD1 1 ATOM 7722 C CD2 . LEU C 2 128 ? 55.947 35.876 -17.573 1.00 49.99 ? 160 LEU C CD2 1 ATOM 7723 N N . PRO C 2 129 ? 54.531 40.909 -19.701 1.00 60.21 ? 161 PRO C N 1 ATOM 7724 C CA . PRO C 2 129 ? 53.653 42.085 -19.786 1.00 60.10 ? 161 PRO C CA 1 ATOM 7725 C C . PRO C 2 129 ? 52.250 41.977 -19.151 1.00 57.90 ? 161 PRO C C 1 ATOM 7726 O O . PRO C 2 129 ? 51.832 40.902 -18.719 1.00 55.86 ? 161 PRO C O 1 ATOM 7727 C CB . PRO C 2 129 ? 53.539 42.306 -21.306 1.00 60.57 ? 161 PRO C CB 1 ATOM 7728 C CG . PRO C 2 129 ? 53.627 40.934 -21.881 1.00 59.50 ? 161 PRO C CG 1 ATOM 7729 C CD . PRO C 2 129 ? 54.630 40.223 -21.007 1.00 60.46 ? 161 PRO C CD 1 ATOM 7730 N N . VAL C 2 130 ? 51.570 43.132 -19.122 1.00 58.44 ? 162 VAL C N 1 ATOM 7731 C CA . VAL C 2 130 ? 50.167 43.322 -18.691 1.00 55.82 ? 162 VAL C CA 1 ATOM 7732 C C . VAL C 2 130 ? 49.155 42.781 -19.714 1.00 53.43 ? 162 VAL C C 1 ATOM 7733 O O . VAL C 2 130 ? 48.071 42.305 -19.368 1.00 57.19 ? 162 VAL C O 1 ATOM 7734 C CB . VAL C 2 130 ? 49.858 44.839 -18.552 1.00 55.48 ? 162 VAL C CB 1 ATOM 7735 C CG1 . VAL C 2 130 ? 48.402 45.086 -18.123 1.00 55.14 ? 162 VAL C CG1 1 ATOM 7736 C CG2 . VAL C 2 130 ? 50.855 45.505 -17.613 1.00 56.34 ? 162 VAL C CG2 1 ATOM 7737 N N . VAL C 2 131 ? 49.516 42.886 -20.979 1.00 47.73 ? 163 VAL C N 1 ATOM 7738 C CA . VAL C 2 131 ? 48.595 42.673 -22.064 1.00 45.72 ? 163 VAL C CA 1 ATOM 7739 C C . VAL C 2 131 ? 49.045 41.465 -22.825 1.00 45.17 ? 163 VAL C C 1 ATOM 7740 O O . VAL C 2 131 ? 50.128 40.945 -22.572 1.00 48.03 ? 163 VAL C O 1 ATOM 7741 C CB . VAL C 2 131 ? 48.585 43.883 -23.014 1.00 46.16 ? 163 VAL C CB 1 ATOM 7742 C CG1 . VAL C 2 131 ? 48.249 45.157 -22.236 1.00 45.51 ? 163 VAL C CG1 1 ATOM 7743 C CG2 . VAL C 2 131 ? 49.911 44.005 -23.779 1.00 44.80 ? 163 VAL C CG2 1 ATOM 7744 N N . THR C 2 132 ? 48.225 41.038 -23.776 1.00 44.39 ? 164 THR C N 1 ATOM 7745 C CA . THR C 2 132 ? 48.542 39.865 -24.588 1.00 44.77 ? 164 THR C CA 1 ATOM 7746 C C . THR C 2 132 ? 49.877 40.055 -25.347 1.00 41.86 ? 164 THR C C 1 ATOM 7747 O O . THR C 2 132 ? 50.351 41.201 -25.547 1.00 38.37 ? 164 THR C O 1 ATOM 7748 C CB . THR C 2 132 ? 47.358 39.439 -25.518 1.00 46.73 ? 164 THR C CB 1 ATOM 7749 O OG1 . THR C 2 132 ? 47.612 38.133 -26.075 1.00 45.31 ? 164 THR C OG1 1 ATOM 7750 C CG2 . THR C 2 132 ? 47.120 40.468 -26.647 1.00 47.08 ? 164 THR C CG2 1 ATOM 7751 N N . SER C 2 133 ? 50.471 38.910 -25.712 1.00 38.70 ? 165 SER C N 1 ATOM 7752 C CA . SER C 2 133 ? 51.868 38.820 -26.149 1.00 37.29 ? 165 SER C CA 1 ATOM 7753 C C . SER C 2 133 ? 52.099 37.519 -26.906 1.00 37.20 ? 165 SER C C 1 ATOM 7754 O O . SER C 2 133 ? 51.337 36.574 -26.748 1.00 37.01 ? 165 SER C O 1 ATOM 7755 C CB . SER C 2 133 ? 52.819 38.876 -24.941 1.00 37.21 ? 165 SER C CB 1 ATOM 7756 O OG . SER C 2 133 ? 53.072 37.581 -24.427 1.00 35.80 ? 165 SER C OG 1 ATOM 7757 N N . LYS C 2 134 ? 53.167 37.474 -27.704 1.00 39.09 ? 166 LYS C N 1 ATOM 7758 C CA . LYS C 2 134 ? 53.441 36.327 -28.595 1.00 41.20 ? 166 LYS C CA 1 ATOM 7759 C C . LYS C 2 134 ? 53.768 35.037 -27.801 1.00 42.63 ? 166 LYS C C 1 ATOM 7760 O O . LYS C 2 134 ? 53.497 33.927 -28.274 1.00 42.74 ? 166 LYS C O 1 ATOM 7761 C CB . LYS C 2 134 ? 54.521 36.681 -29.664 1.00 39.58 ? 166 LYS C CB 1 ATOM 7762 C CG . LYS C 2 134 ? 55.443 35.531 -30.052 1.00 38.38 ? 166 LYS C CG 1 ATOM 7763 C CD . LYS C 2 134 ? 56.152 35.739 -31.367 1.00 37.03 ? 166 LYS C CD 1 ATOM 7764 C CE . LYS C 2 134 ? 55.280 35.218 -32.481 1.00 37.32 ? 166 LYS C CE 1 ATOM 7765 N NZ . LYS C 2 134 ? 56.039 35.251 -33.741 1.00 37.29 1 166 LYS C NZ 1 ATOM 7766 N N . VAL C 2 135 ? 54.315 35.197 -26.594 1.00 45.11 ? 167 VAL C N 1 ATOM 7767 C CA . VAL C 2 135 ? 54.616 34.066 -25.681 1.00 45.53 ? 167 VAL C CA 1 ATOM 7768 C C . VAL C 2 135 ? 53.339 33.562 -24.953 1.00 41.48 ? 167 VAL C C 1 ATOM 7769 O O . VAL C 2 135 ? 53.042 32.365 -24.927 1.00 37.99 ? 167 VAL C O 1 ATOM 7770 C CB . VAL C 2 135 ? 55.717 34.474 -24.649 1.00 46.25 ? 167 VAL C CB 1 ATOM 7771 C CG1 . VAL C 2 135 ? 56.033 33.342 -23.678 1.00 45.26 ? 167 VAL C CG1 1 ATOM 7772 C CG2 . VAL C 2 135 ? 56.975 34.926 -25.378 1.00 47.01 ? 167 VAL C CG2 1 ATOM 7773 N N . TYR C 2 136 ? 52.590 34.491 -24.377 1.00 39.14 ? 168 TYR C N 1 ATOM 7774 C CA . TYR C 2 136 ? 51.309 34.184 -23.751 1.00 39.75 ? 168 TYR C CA 1 ATOM 7775 C C . TYR C 2 136 ? 50.364 33.387 -24.687 1.00 40.81 ? 168 TYR C C 1 ATOM 7776 O O . TYR C 2 136 ? 49.588 32.521 -24.247 1.00 38.18 ? 168 TYR C O 1 ATOM 7777 C CB . TYR C 2 136 ? 50.643 35.499 -23.305 1.00 38.92 ? 168 TYR C CB 1 ATOM 7778 C CG . TYR C 2 136 ? 51.272 36.197 -22.095 1.00 37.51 ? 168 TYR C CG 1 ATOM 7779 C CD1 . TYR C 2 136 ? 52.378 35.649 -21.403 1.00 37.97 ? 168 TYR C CD1 1 ATOM 7780 C CD2 . TYR C 2 136 ? 50.729 37.380 -21.610 1.00 35.40 ? 168 TYR C CD2 1 ATOM 7781 C CE1 . TYR C 2 136 ? 52.921 36.279 -20.286 1.00 35.85 ? 168 TYR C CE1 1 ATOM 7782 C CE2 . TYR C 2 136 ? 51.268 38.013 -20.504 1.00 36.19 ? 168 TYR C CE2 1 ATOM 7783 C CZ . TYR C 2 136 ? 52.356 37.456 -19.839 1.00 35.76 ? 168 TYR C CZ 1 ATOM 7784 O OH . TYR C 2 136 ? 52.880 38.097 -18.742 1.00 33.92 ? 168 TYR C OH 1 ATOM 7785 N N . ASN C 2 137 ? 50.439 33.692 -25.979 1.00 42.30 ? 169 ASN C N 1 ATOM 7786 C CA . ASN C 2 137 ? 49.633 33.007 -26.979 1.00 43.79 ? 169 ASN C CA 1 ATOM 7787 C C . ASN C 2 137 ? 50.269 31.704 -27.395 1.00 46.69 ? 169 ASN C C 1 ATOM 7788 O O . ASN C 2 137 ? 49.557 30.723 -27.659 1.00 48.21 ? 169 ASN C O 1 ATOM 7789 C CB . ASN C 2 137 ? 49.417 33.900 -28.196 1.00 42.11 ? 169 ASN C CB 1 ATOM 7790 C CG . ASN C 2 137 ? 48.418 35.004 -27.922 1.00 42.45 ? 169 ASN C CG 1 ATOM 7791 O OD1 . ASN C 2 137 ? 48.793 36.169 -27.769 1.00 43.59 ? 169 ASN C OD1 1 ATOM 7792 N ND2 . ASN C 2 137 ? 47.135 34.641 -27.825 1.00 41.15 ? 169 ASN C ND2 1 ATOM 7793 N N . ALA C 2 138 ? 51.604 31.709 -27.458 1.00 47.90 ? 170 ALA C N 1 ATOM 7794 C CA . ALA C 2 138 ? 52.392 30.523 -27.819 1.00 50.06 ? 170 ALA C CA 1 ATOM 7795 C C . ALA C 2 138 ? 52.210 29.373 -26.821 1.00 53.89 ? 170 ALA C C 1 ATOM 7796 O O . ALA C 2 138 ? 52.115 28.205 -27.223 1.00 55.32 ? 170 ALA C O 1 ATOM 7797 C CB . ALA C 2 138 ? 53.869 30.877 -27.949 1.00 48.77 ? 170 ALA C CB 1 ATOM 7798 N N . VAL C 2 139 ? 52.167 29.708 -25.528 1.00 53.93 ? 171 VAL C N 1 ATOM 7799 C CA . VAL C 2 139 ? 51.903 28.710 -24.477 1.00 51.25 ? 171 VAL C CA 1 ATOM 7800 C C . VAL C 2 139 ? 50.430 28.301 -24.421 1.00 50.27 ? 171 VAL C C 1 ATOM 7801 O O . VAL C 2 139 ? 50.132 27.121 -24.274 1.00 49.61 ? 171 VAL C O 1 ATOM 7802 C CB . VAL C 2 139 ? 52.389 29.161 -23.075 1.00 49.59 ? 171 VAL C CB 1 ATOM 7803 C CG1 . VAL C 2 139 ? 53.883 29.410 -23.107 1.00 49.92 ? 171 VAL C CG1 1 ATOM 7804 C CG2 . VAL C 2 139 ? 51.649 30.392 -22.561 1.00 49.43 ? 171 VAL C CG2 1 ATOM 7805 N N . ALA C 2 140 ? 49.513 29.258 -24.557 1.00 49.17 ? 172 ALA C N 1 ATOM 7806 C CA . ALA C 2 140 ? 48.089 28.928 -24.565 1.00 49.44 ? 172 ALA C CA 1 ATOM 7807 C C . ALA C 2 140 ? 47.782 27.800 -25.571 1.00 49.72 ? 172 ALA C C 1 ATOM 7808 O O . ALA C 2 140 ? 46.926 26.953 -25.305 1.00 46.85 ? 172 ALA C O 1 ATOM 7809 C CB . ALA C 2 140 ? 47.245 30.166 -24.841 1.00 48.10 ? 172 ALA C CB 1 ATOM 7810 N N . ASN C 2 141 ? 48.497 27.778 -26.700 1.00 52.04 ? 173 ASN C N 1 ATOM 7811 C CA . ASN C 2 141 ? 48.368 26.692 -27.695 1.00 57.13 ? 173 ASN C CA 1 ATOM 7812 C C . ASN C 2 141 ? 49.010 25.370 -27.232 1.00 55.36 ? 173 ASN C C 1 ATOM 7813 O O . ASN C 2 141 ? 48.438 24.285 -27.394 1.00 56.78 ? 173 ASN C O 1 ATOM 7814 C CB . ASN C 2 141 ? 48.963 27.106 -29.058 1.00 59.60 ? 173 ASN C CB 1 ATOM 7815 C CG . ASN C 2 141 ? 48.240 28.298 -29.691 1.00 63.19 ? 173 ASN C CG 1 ATOM 7816 O OD1 . ASN C 2 141 ? 47.117 28.657 -29.314 1.00 61.88 ? 173 ASN C OD1 1 ATOM 7817 N ND2 . ASN C 2 141 ? 48.894 28.920 -30.663 1.00 65.95 ? 173 ASN C ND2 1 ATOM 7818 N N . LEU C 2 142 ? 50.203 25.479 -26.658 1.00 51.68 ? 174 LEU C N 1 ATOM 7819 C CA . LEU C 2 142 ? 50.943 24.331 -26.151 1.00 46.33 ? 174 LEU C CA 1 ATOM 7820 C C . LEU C 2 142 ? 50.232 23.643 -24.996 1.00 44.41 ? 174 LEU C C 1 ATOM 7821 O O . LEU C 2 142 ? 50.320 22.427 -24.860 1.00 43.45 ? 174 LEU C O 1 ATOM 7822 C CB . LEU C 2 142 ? 52.323 24.784 -25.680 1.00 46.99 ? 174 LEU C CB 1 ATOM 7823 C CG . LEU C 2 142 ? 53.299 25.256 -26.757 1.00 47.57 ? 174 LEU C CG 1 ATOM 7824 C CD1 . LEU C 2 142 ? 54.343 26.195 -26.169 1.00 47.79 ? 174 LEU C CD1 1 ATOM 7825 C CD2 . LEU C 2 142 ? 53.962 24.066 -27.437 1.00 46.86 ? 174 LEU C CD2 1 ATOM 7826 N N . TRP C 2 143 ? 49.553 24.429 -24.157 1.00 45.04 ? 175 TRP C N 1 ATOM 7827 C CA . TRP C 2 143 ? 48.903 23.923 -22.935 1.00 45.50 ? 175 TRP C CA 1 ATOM 7828 C C . TRP C 2 143 ? 47.384 23.809 -23.063 1.00 47.74 ? 175 TRP C C 1 ATOM 7829 O O . TRP C 2 143 ? 46.687 23.630 -22.062 1.00 49.18 ? 175 TRP C O 1 ATOM 7830 C CB . TRP C 2 143 ? 49.278 24.786 -21.717 1.00 43.06 ? 175 TRP C CB 1 ATOM 7831 C CG . TRP C 2 143 ? 50.759 24.870 -21.517 1.00 42.62 ? 175 TRP C CG 1 ATOM 7832 C CD1 . TRP C 2 143 ? 51.705 23.985 -21.974 1.00 42.55 ? 175 TRP C CD1 1 ATOM 7833 C CD2 . TRP C 2 143 ? 51.478 25.889 -20.812 1.00 43.31 ? 175 TRP C CD2 1 ATOM 7834 N NE1 . TRP C 2 143 ? 52.964 24.399 -21.610 1.00 42.37 ? 175 TRP C NE1 1 ATOM 7835 C CE2 . TRP C 2 143 ? 52.856 25.561 -20.890 1.00 42.52 ? 175 TRP C CE2 1 ATOM 7836 C CE3 . TRP C 2 143 ? 51.095 27.046 -20.113 1.00 45.26 ? 175 TRP C CE3 1 ATOM 7837 C CZ2 . TRP C 2 143 ? 53.851 26.346 -20.292 1.00 42.02 ? 175 TRP C CZ2 1 ATOM 7838 C CZ3 . TRP C 2 143 ? 52.090 27.833 -19.515 1.00 44.24 ? 175 TRP C CZ3 1 ATOM 7839 C CH2 . TRP C 2 143 ? 53.449 27.474 -19.612 1.00 43.41 ? 175 TRP C CH2 1 ATOM 7840 N N . LYS C 2 144 ? 46.874 23.882 -24.292 1.00 48.85 ? 176 LYS C N 1 ATOM 7841 C CA . LYS C 2 144 ? 45.469 23.595 -24.532 1.00 49.28 ? 176 LYS C CA 1 ATOM 7842 C C . LYS C 2 144 ? 45.109 22.199 -24.053 1.00 46.57 ? 176 LYS C C 1 ATOM 7843 O O . LYS C 2 144 ? 44.138 22.064 -23.308 1.00 49.96 ? 176 LYS C O 1 ATOM 7844 C CB . LYS C 2 144 ? 45.074 23.800 -26.004 1.00 53.56 ? 176 LYS C CB 1 ATOM 7845 C CG . LYS C 2 144 ? 44.192 25.035 -26.226 1.00 57.47 ? 176 LYS C CG 1 ATOM 7846 C CD . LYS C 2 144 ? 44.508 25.794 -27.516 1.00 59.54 ? 176 LYS C CD 1 ATOM 7847 C CE . LYS C 2 144 ? 44.358 24.938 -28.766 1.00 61.73 ? 176 LYS C CE 1 ATOM 7848 N NZ . LYS C 2 144 ? 44.820 25.670 -29.974 1.00 64.08 1 176 LYS C NZ 1 ATOM 7849 N N . PRO C 2 145 ? 45.909 21.170 -24.417 1.00 42.93 ? 177 PRO C N 1 ATOM 7850 C CA . PRO C 2 145 ? 45.570 19.772 -24.070 1.00 42.68 ? 177 PRO C CA 1 ATOM 7851 C C . PRO C 2 145 ? 45.285 19.529 -22.582 1.00 44.60 ? 177 PRO C C 1 ATOM 7852 O O . PRO C 2 145 ? 44.679 18.522 -22.220 1.00 44.12 ? 177 PRO C O 1 ATOM 7853 C CB . PRO C 2 145 ? 46.821 18.991 -24.479 1.00 41.85 ? 177 PRO C CB 1 ATOM 7854 C CG . PRO C 2 145 ? 47.510 19.841 -25.478 1.00 41.81 ? 177 PRO C CG 1 ATOM 7855 C CD . PRO C 2 145 ? 47.214 21.259 -25.095 1.00 42.16 ? 177 PRO C CD 1 ATOM 7856 N N . TRP C 2 146 ? 45.733 20.454 -21.736 1.00 47.89 ? 178 TRP C N 1 ATOM 7857 C CA . TRP C 2 146 ? 45.556 20.372 -20.294 1.00 46.05 ? 178 TRP C CA 1 ATOM 7858 C C . TRP C 2 146 ? 44.594 21.404 -19.704 1.00 48.03 ? 178 TRP C C 1 ATOM 7859 O O . TRP C 2 146 ? 44.293 21.320 -18.518 1.00 48.58 ? 178 TRP C O 1 ATOM 7860 C CB . TRP C 2 146 ? 46.906 20.578 -19.611 1.00 44.41 ? 178 TRP C CB 1 ATOM 7861 C CG . TRP C 2 146 ? 47.974 19.610 -19.986 1.00 41.73 ? 178 TRP C CG 1 ATOM 7862 C CD1 . TRP C 2 146 ? 47.827 18.279 -20.239 1.00 41.56 ? 178 TRP C CD1 1 ATOM 7863 C CD2 . TRP C 2 146 ? 49.367 19.895 -20.104 1.00 40.35 ? 178 TRP C CD2 1 ATOM 7864 N NE1 . TRP C 2 146 ? 49.046 17.718 -20.520 1.00 41.94 ? 178 TRP C NE1 1 ATOM 7865 C CE2 . TRP C 2 146 ? 50.011 18.689 -20.444 1.00 42.04 ? 178 TRP C CE2 1 ATOM 7866 C CE3 . TRP C 2 146 ? 50.132 21.055 -19.970 1.00 40.73 ? 178 TRP C CE3 1 ATOM 7867 C CZ2 . TRP C 2 146 ? 51.398 18.606 -20.641 1.00 42.54 ? 178 TRP C CZ2 1 ATOM 7868 C CZ3 . TRP C 2 146 ? 51.508 20.978 -20.174 1.00 41.61 ? 178 TRP C CZ3 1 ATOM 7869 C CH2 . TRP C 2 146 ? 52.128 19.758 -20.500 1.00 42.31 ? 178 TRP C CH2 1 ATOM 7870 N N . LEU C 2 147 ? 44.125 22.380 -20.478 1.00 51.05 ? 179 LEU C N 1 ATOM 7871 C CA . LEU C 2 147 ? 43.340 23.453 -19.878 1.00 57.89 ? 179 LEU C CA 1 ATOM 7872 C C . LEU C 2 147 ? 42.006 23.785 -20.590 1.00 61.40 ? 179 LEU C C 1 ATOM 7873 O O . LEU C 2 147 ? 41.843 23.534 -21.789 1.00 60.87 ? 179 LEU C O 1 ATOM 7874 C CB . LEU C 2 147 ? 44.221 24.703 -19.718 1.00 60.67 ? 179 LEU C CB 1 ATOM 7875 C CG . LEU C 2 147 ? 45.558 24.528 -18.957 1.00 65.20 ? 179 LEU C CG 1 ATOM 7876 C CD1 . LEU C 2 147 ? 46.374 25.824 -18.969 1.00 68.40 ? 179 LEU C CD1 1 ATOM 7877 C CD2 . LEU C 2 147 ? 45.397 24.041 -17.515 1.00 63.68 ? 179 LEU C CD2 1 ATOM 7878 N N . ASP C 2 148 ? 41.064 24.325 -19.801 1.00 61.32 ? 180 ASP C N 1 ATOM 7879 C CA . ASP C 2 148 ? 39.762 24.845 -20.257 1.00 61.34 ? 180 ASP C CA 1 ATOM 7880 C C . ASP C 2 148 ? 39.901 25.842 -21.396 1.00 62.84 ? 180 ASP C C 1 ATOM 7881 O O . ASP C 2 148 ? 40.992 26.293 -21.690 1.00 62.95 ? 180 ASP C O 1 ATOM 7882 C CB . ASP C 2 148 ? 39.064 25.601 -19.105 1.00 62.83 ? 180 ASP C CB 1 ATOM 7883 C CG . ASP C 2 148 ? 38.077 24.753 -18.299 1.00 63.67 ? 180 ASP C CG 1 ATOM 7884 O OD1 . ASP C 2 148 ? 37.861 23.553 -18.578 1.00 61.10 ? 180 ASP C OD1 1 ATOM 7885 O OD2 . ASP C 2 148 ? 37.491 25.333 -17.359 1.00 64.62 -1 180 ASP C OD2 1 ATOM 7886 N N . GLU C 2 149 ? 38.779 26.197 -22.019 1.00 70.26 ? 181 GLU C N 1 ATOM 7887 C CA . GLU C 2 149 ? 38.701 27.400 -22.868 1.00 71.31 ? 181 GLU C CA 1 ATOM 7888 C C . GLU C 2 149 ? 38.779 28.624 -21.958 1.00 67.96 ? 181 GLU C C 1 ATOM 7889 O O . GLU C 2 149 ? 39.301 29.667 -22.344 1.00 63.91 ? 181 GLU C O 1 ATOM 7890 C CB . GLU C 2 149 ? 37.364 27.502 -23.614 1.00 74.28 ? 181 GLU C CB 1 ATOM 7891 C CG . GLU C 2 149 ? 36.926 26.297 -24.435 1.00 75.47 ? 181 GLU C CG 1 ATOM 7892 C CD . GLU C 2 149 ? 35.423 26.292 -24.688 1.00 74.42 ? 181 GLU C CD 1 ATOM 7893 O OE1 . GLU C 2 149 ? 34.756 27.326 -24.468 1.00 69.87 ? 181 GLU C OE1 1 ATOM 7894 O OE2 . GLU C 2 149 ? 34.904 25.245 -25.112 1.00 73.33 -1 181 GLU C OE2 1 ATOM 7895 N N . GLU C 2 150 ? 38.196 28.477 -20.768 1.00 64.77 ? 182 GLU C N 1 ATOM 7896 C CA . GLU C 2 150 ? 38.131 29.523 -19.759 1.00 65.40 ? 182 GLU C CA 1 ATOM 7897 C C . GLU C 2 150 ? 39.519 29.853 -19.211 1.00 61.88 ? 182 GLU C C 1 ATOM 7898 O O . GLU C 2 150 ? 39.897 31.025 -19.099 1.00 58.71 ? 182 GLU C O 1 ATOM 7899 C CB . GLU C 2 150 ? 37.198 29.090 -18.613 1.00 69.66 ? 182 GLU C CB 1 ATOM 7900 C CG . GLU C 2 150 ? 35.711 28.989 -18.975 1.00 73.42 ? 182 GLU C CG 1 ATOM 7901 C CD . GLU C 2 150 ? 35.318 27.666 -19.636 1.00 77.28 ? 182 GLU C CD 1 ATOM 7902 O OE1 . GLU C 2 150 ? 35.273 26.618 -18.946 1.00 72.66 ? 182 GLU C OE1 1 ATOM 7903 O OE2 . GLU C 2 150 ? 35.039 27.677 -20.857 1.00 82.25 -1 182 GLU C OE2 1 ATOM 7904 N N . ALA C 2 151 ? 40.266 28.811 -18.875 1.00 57.68 ? 183 ALA C N 1 ATOM 7905 C CA . ALA C 2 151 ? 41.606 28.960 -18.337 1.00 57.82 ? 183 ALA C CA 1 ATOM 7906 C C . ALA C 2 151 ? 42.490 29.630 -19.371 1.00 57.77 ? 183 ALA C C 1 ATOM 7907 O O . ALA C 2 151 ? 43.117 30.660 -19.102 1.00 58.46 ? 183 ALA C O 1 ATOM 7908 C CB . ALA C 2 151 ? 42.171 27.599 -17.966 1.00 58.67 ? 183 ALA C CB 1 ATOM 7909 N N . ILE C 2 152 ? 42.513 29.024 -20.556 1.00 57.59 ? 184 ILE C N 1 ATOM 7910 C CA . ILE C 2 152 ? 43.248 29.529 -21.729 1.00 57.32 ? 184 ILE C CA 1 ATOM 7911 C C . ILE C 2 152 ? 42.962 31.021 -22.049 1.00 56.54 ? 184 ILE C C 1 ATOM 7912 O O . ILE C 2 152 ? 43.862 31.752 -22.460 1.00 53.41 ? 184 ILE C O 1 ATOM 7913 C CB . ILE C 2 152 ? 42.965 28.616 -22.960 1.00 54.75 ? 184 ILE C CB 1 ATOM 7914 C CG1 . ILE C 2 152 ? 43.710 27.273 -22.823 1.00 53.98 ? 184 ILE C CG1 1 ATOM 7915 C CG2 . ILE C 2 152 ? 43.307 29.291 -24.282 1.00 55.57 ? 184 ILE C CG2 1 ATOM 7916 C CD1 . ILE C 2 152 ? 45.219 27.334 -22.913 1.00 53.05 ? 184 ILE C CD1 1 ATOM 7917 N N . SER C 2 153 ? 41.726 31.466 -21.846 1.00 58.41 ? 185 SER C N 1 ATOM 7918 C CA . SER C 2 153 ? 41.361 32.866 -22.080 1.00 62.16 ? 185 SER C CA 1 ATOM 7919 C C . SER C 2 153 ? 42.300 33.807 -21.348 1.00 62.61 ? 185 SER C C 1 ATOM 7920 O O . SER C 2 153 ? 42.873 34.703 -21.961 1.00 63.63 ? 185 SER C O 1 ATOM 7921 C CB . SER C 2 153 ? 39.934 33.152 -21.604 1.00 65.43 ? 185 SER C CB 1 ATOM 7922 O OG . SER C 2 153 ? 39.081 32.058 -21.875 1.00 71.31 ? 185 SER C OG 1 ATOM 7923 N N . THR C 2 154 ? 42.441 33.588 -20.036 1.00 59.08 ? 186 THR C N 1 ATOM 7924 C CA . THR C 2 154 ? 43.293 34.422 -19.176 1.00 52.87 ? 186 THR C CA 1 ATOM 7925 C C . THR C 2 154 ? 44.787 34.116 -19.339 1.00 50.99 ? 186 THR C C 1 ATOM 7926 O O . THR C 2 154 ? 45.632 34.976 -19.075 1.00 48.64 ? 186 THR C O 1 ATOM 7927 C CB . THR C 2 154 ? 42.917 34.311 -17.672 1.00 50.35 ? 186 THR C CB 1 ATOM 7928 O OG1 . THR C 2 154 ? 42.180 33.108 -17.428 1.00 47.28 ? 186 THR C OG1 1 ATOM 7929 C CG2 . THR C 2 154 ? 42.101 35.513 -17.226 1.00 49.78 ? 186 THR C CG2 1 ATOM 7930 N N . LEU C 2 155 ? 45.122 32.897 -19.749 1.00 49.71 ? 187 LEU C N 1 ATOM 7931 C CA . LEU C 2 155 ? 46.517 32.563 -20.008 1.00 50.29 ? 187 LEU C CA 1 ATOM 7932 C C . LEU C 2 155 ? 47.125 33.500 -21.060 1.00 52.75 ? 187 LEU C C 1 ATOM 7933 O O . LEU C 2 155 ? 48.211 34.041 -20.846 1.00 54.13 ? 187 LEU C O 1 ATOM 7934 C CB . LEU C 2 155 ? 46.650 31.102 -20.433 1.00 49.39 ? 187 LEU C CB 1 ATOM 7935 C CG . LEU C 2 155 ? 48.075 30.530 -20.483 1.00 48.96 ? 187 LEU C CG 1 ATOM 7936 C CD1 . LEU C 2 155 ? 48.931 30.856 -19.252 1.00 47.30 ? 187 LEU C CD1 1 ATOM 7937 C CD2 . LEU C 2 155 ? 47.989 29.027 -20.700 1.00 49.00 ? 187 LEU C CD2 1 ATOM 7938 N N . ARG C 2 156 ? 46.403 33.714 -22.165 1.00 55.02 ? 188 ARG C N 1 ATOM 7939 C CA . ARG C 2 156 ? 46.801 34.673 -23.229 1.00 54.57 ? 188 ARG C CA 1 ATOM 7940 C C . ARG C 2 156 ? 46.775 36.125 -22.768 1.00 55.09 ? 188 ARG C C 1 ATOM 7941 O O . ARG C 2 156 ? 47.592 36.914 -23.210 1.00 60.57 ? 188 ARG C O 1 ATOM 7942 C CB . ARG C 2 156 ? 45.862 34.610 -24.439 1.00 55.52 ? 188 ARG C CB 1 ATOM 7943 C CG . ARG C 2 156 ? 45.565 33.224 -24.990 1.00 57.35 ? 188 ARG C CG 1 ATOM 7944 C CD . ARG C 2 156 ? 44.489 33.294 -26.058 1.00 55.89 ? 188 ARG C CD 1 ATOM 7945 N NE . ARG C 2 156 ? 43.976 31.986 -26.474 1.00 53.23 ? 188 ARG C NE 1 ATOM 7946 C CZ . ARG C 2 156 ? 44.637 31.084 -27.208 1.00 51.18 ? 188 ARG C CZ 1 ATOM 7947 N NH1 . ARG C 2 156 ? 45.900 31.277 -27.619 1.00 48.33 1 188 ARG C NH1 1 ATOM 7948 N NH2 . ARG C 2 156 ? 44.015 29.952 -27.520 1.00 51.54 ? 188 ARG C NH2 1 ATOM 7949 N N . LYS C 2 157 ? 45.797 36.478 -21.931 1.00 54.60 ? 189 LYS C N 1 ATOM 7950 C CA . LYS C 2 157 ? 45.635 37.847 -21.421 1.00 54.78 ? 189 LYS C CA 1 ATOM 7951 C C . LYS C 2 157 ? 46.813 38.296 -20.535 1.00 55.03 ? 189 LYS C C 1 ATOM 7952 O O . LYS C 2 157 ? 47.395 39.355 -20.792 1.00 57.21 ? 189 LYS C O 1 ATOM 7953 C CB . LYS C 2 157 ? 44.305 38.005 -20.640 1.00 57.31 ? 189 LYS C CB 1 ATOM 7954 C CG . LYS C 2 157 ? 43.087 38.561 -21.395 1.00 56.49 ? 189 LYS C CG 1 ATOM 7955 C CD . LYS C 2 157 ? 42.561 37.626 -22.479 1.00 60.20 ? 189 LYS C CD 1 ATOM 7956 C CE . LYS C 2 157 ? 42.993 38.057 -23.894 1.00 64.54 ? 189 LYS C CE 1 ATOM 7957 N NZ . LYS C 2 157 ? 42.959 36.977 -24.934 1.00 62.99 1 189 LYS C NZ 1 ATOM 7958 N N . GLY C 2 158 ? 47.154 37.505 -19.505 1.00 55.83 ? 190 GLY C N 1 ATOM 7959 C CA . GLY C 2 158 ? 48.174 37.899 -18.493 1.00 54.05 ? 190 GLY C CA 1 ATOM 7960 C C . GLY C 2 158 ? 49.242 36.903 -18.041 1.00 49.52 ? 190 GLY C C 1 ATOM 7961 O O . GLY C 2 158 ? 50.119 37.254 -17.261 1.00 43.75 ? 190 GLY C O 1 ATOM 7962 N N . GLY C 2 159 ? 49.194 35.676 -18.543 1.00 49.72 ? 191 GLY C N 1 ATOM 7963 C CA . GLY C 2 159 ? 50.123 34.633 -18.102 1.00 51.41 ? 191 GLY C CA 1 ATOM 7964 C C . GLY C 2 159 ? 49.541 33.683 -17.059 1.00 50.92 ? 191 GLY C C 1 ATOM 7965 O O . GLY C 2 159 ? 50.209 32.724 -16.653 1.00 47.82 ? 191 GLY C O 1 ATOM 7966 N N . PHE C 2 160 ? 48.288 33.925 -16.658 1.00 48.24 ? 192 PHE C N 1 ATOM 7967 C CA . PHE C 2 160 ? 47.661 33.176 -15.570 1.00 44.99 ? 192 PHE C CA 1 ATOM 7968 C C . PHE C 2 160 ? 46.290 32.578 -15.910 1.00 44.17 ? 192 PHE C C 1 ATOM 7969 O O . PHE C 2 160 ? 45.714 32.828 -16.958 1.00 42.32 ? 192 PHE C O 1 ATOM 7970 C CB . PHE C 2 160 ? 47.562 34.051 -14.333 1.00 42.12 ? 192 PHE C CB 1 ATOM 7971 C CG . PHE C 2 160 ? 46.749 35.276 -14.530 1.00 41.77 ? 192 PHE C CG 1 ATOM 7972 C CD1 . PHE C 2 160 ? 45.400 35.281 -14.212 1.00 41.96 ? 192 PHE C CD1 1 ATOM 7973 C CD2 . PHE C 2 160 ? 47.336 36.441 -15.014 1.00 41.66 ? 192 PHE C CD2 1 ATOM 7974 C CE1 . PHE C 2 160 ? 44.644 36.430 -14.378 1.00 41.64 ? 192 PHE C CE1 1 ATOM 7975 C CE2 . PHE C 2 160 ? 46.591 37.594 -15.170 1.00 41.84 ? 192 PHE C CE2 1 ATOM 7976 C CZ . PHE C 2 160 ? 45.240 37.587 -14.857 1.00 42.02 ? 192 PHE C CZ 1 ATOM 7977 N N . TYR C 2 161 ? 45.797 31.750 -15.001 1.00 45.08 ? 193 TYR C N 1 ATOM 7978 C CA . TYR C 2 161 ? 44.583 30.984 -15.215 1.00 45.89 ? 193 TYR C CA 1 ATOM 7979 C C . TYR C 2 161 ? 44.231 30.244 -13.944 1.00 44.66 ? 193 TYR C C 1 ATOM 7980 O O . TYR C 2 161 ? 45.050 30.163 -13.054 1.00 46.76 ? 193 TYR C O 1 ATOM 7981 C CB . TYR C 2 161 ? 44.797 29.970 -16.338 1.00 46.23 ? 193 TYR C CB 1 ATOM 7982 C CG . TYR C 2 161 ? 45.767 28.825 -16.048 1.00 45.25 ? 193 TYR C CG 1 ATOM 7983 C CD1 . TYR C 2 161 ? 47.092 28.875 -16.467 1.00 43.47 ? 193 TYR C CD1 1 ATOM 7984 C CD2 . TYR C 2 161 ? 45.340 27.668 -15.409 1.00 46.58 ? 193 TYR C CD2 1 ATOM 7985 C CE1 . TYR C 2 161 ? 47.960 27.815 -16.253 1.00 40.54 ? 193 TYR C CE1 1 ATOM 7986 C CE2 . TYR C 2 161 ? 46.212 26.606 -15.182 1.00 44.13 ? 193 TYR C CE2 1 ATOM 7987 C CZ . TYR C 2 161 ? 47.513 26.686 -15.610 1.00 40.67 ? 193 TYR C CZ 1 ATOM 7988 O OH . TYR C 2 161 ? 48.344 25.626 -15.371 1.00 38.94 ? 193 TYR C OH 1 ATOM 7989 N N . SER C 2 162 ? 43.029 29.702 -13.849 1.00 42.79 ? 194 SER C N 1 ATOM 7990 C CA . SER C 2 162 ? 42.718 28.807 -12.750 1.00 43.60 ? 194 SER C CA 1 ATOM 7991 C C . SER C 2 162 ? 41.994 27.647 -13.347 1.00 46.10 ? 194 SER C C 1 ATOM 7992 O O . SER C 2 162 ? 41.492 27.760 -14.457 1.00 51.59 ? 194 SER C O 1 ATOM 7993 C CB . SER C 2 162 ? 41.842 29.480 -11.710 1.00 43.34 ? 194 SER C CB 1 ATOM 7994 O OG . SER C 2 162 ? 40.526 29.582 -12.194 1.00 43.38 ? 194 SER C OG 1 ATOM 7995 N N . GLN C 2 163 ? 41.915 26.533 -12.630 1.00 47.02 ? 195 GLN C N 1 ATOM 7996 C CA . GLN C 2 163 ? 41.427 25.306 -13.257 1.00 46.93 ? 195 GLN C CA 1 ATOM 7997 C C . GLN C 2 163 ? 41.113 24.172 -12.272 1.00 46.53 ? 195 GLN C C 1 ATOM 7998 O O . GLN C 2 163 ? 41.980 23.726 -11.506 1.00 47.12 ? 195 GLN C O 1 ATOM 7999 C CB . GLN C 2 163 ? 42.470 24.842 -14.307 1.00 46.62 ? 195 GLN C CB 1 ATOM 8000 C CG . GLN C 2 163 ? 42.192 23.523 -15.042 1.00 45.20 ? 195 GLN C CG 1 ATOM 8001 C CD . GLN C 2 163 ? 41.120 23.629 -16.106 1.00 41.72 ? 195 GLN C CD 1 ATOM 8002 O OE1 . GLN C 2 163 ? 41.028 24.630 -16.817 1.00 42.68 ? 195 GLN C OE1 1 ATOM 8003 N NE2 . GLN C 2 163 ? 40.319 22.590 -16.234 1.00 38.74 ? 195 GLN C NE2 1 ATOM 8004 N N . LYS C 2 164 ? 39.878 23.686 -12.336 1.00 44.93 ? 196 LYS C N 1 ATOM 8005 C CA . LYS C 2 164 ? 39.497 22.472 -11.638 1.00 45.30 ? 196 LYS C CA 1 ATOM 8006 C C . LYS C 2 164 ? 40.379 21.342 -12.129 1.00 42.35 ? 196 LYS C C 1 ATOM 8007 O O . LYS C 2 164 ? 40.701 21.288 -13.302 1.00 38.38 ? 196 LYS C O 1 ATOM 8008 C CB . LYS C 2 164 ? 38.033 22.137 -11.924 1.00 50.74 ? 196 LYS C CB 1 ATOM 8009 C CG . LYS C 2 164 ? 37.030 23.146 -11.366 1.00 57.21 ? 196 LYS C CG 1 ATOM 8010 C CD . LYS C 2 164 ? 35.615 22.975 -11.931 1.00 61.43 ? 196 LYS C CD 1 ATOM 8011 C CE . LYS C 2 164 ? 35.478 23.500 -13.362 1.00 64.61 ? 196 LYS C CE 1 ATOM 8012 N NZ . LYS C 2 164 ? 34.071 23.856 -13.690 1.00 65.00 1 196 LYS C NZ 1 ATOM 8013 N N . VAL C 2 165 ? 40.784 20.449 -11.235 1.00 44.78 ? 197 VAL C N 1 ATOM 8014 C CA . VAL C 2 165 ? 41.551 19.266 -11.637 1.00 47.88 ? 197 VAL C CA 1 ATOM 8015 C C . VAL C 2 165 ? 40.595 18.231 -12.203 1.00 50.60 ? 197 VAL C C 1 ATOM 8016 O O . VAL C 2 165 ? 39.524 18.022 -11.641 1.00 49.26 ? 197 VAL C O 1 ATOM 8017 C CB . VAL C 2 165 ? 42.306 18.634 -10.449 1.00 49.40 ? 197 VAL C CB 1 ATOM 8018 C CG1 . VAL C 2 165 ? 42.958 17.306 -10.841 1.00 50.13 ? 197 VAL C CG1 1 ATOM 8019 C CG2 . VAL C 2 165 ? 43.346 19.603 -9.902 1.00 49.68 ? 197 VAL C CG2 1 ATOM 8020 N N . THR C 2 166 ? 40.992 17.580 -13.300 1.00 55.11 ? 198 THR C N 1 ATOM 8021 C CA . THR C 2 166 ? 40.136 16.591 -13.993 1.00 55.96 ? 198 THR C CA 1 ATOM 8022 C C . THR C 2 166 ? 39.753 15.448 -13.065 1.00 55.49 ? 198 THR C C 1 ATOM 8023 O O . THR C 2 166 ? 38.583 15.093 -12.965 1.00 55.47 ? 198 THR C O 1 ATOM 8024 C CB . THR C 2 166 ? 40.806 16.026 -15.277 1.00 54.87 ? 198 THR C CB 1 ATOM 8025 O OG1 . THR C 2 166 ? 40.622 16.957 -16.347 1.00 50.95 ? 198 THR C OG1 1 ATOM 8026 C CG2 . THR C 2 166 ? 40.215 14.655 -15.690 1.00 53.57 ? 198 THR C CG2 1 ATOM 8027 N N . THR C 2 167 ? 40.739 14.891 -12.376 1.00 54.76 ? 199 THR C N 1 ATOM 8028 C CA . THR C 2 167 ? 40.496 13.764 -11.493 1.00 56.10 ? 199 THR C CA 1 ATOM 8029 C C . THR C 2 167 ? 40.013 14.151 -10.102 1.00 52.13 ? 199 THR C C 1 ATOM 8030 O O . THR C 2 167 ? 39.909 13.282 -9.257 1.00 53.66 ? 199 THR C O 1 ATOM 8031 C CB . THR C 2 167 ? 41.770 12.928 -11.306 1.00 60.89 ? 199 THR C CB 1 ATOM 8032 O OG1 . THR C 2 167 ? 42.734 13.692 -10.568 1.00 64.75 ? 199 THR C OG1 1 ATOM 8033 C CG2 . THR C 2 167 ? 42.342 12.510 -12.670 1.00 61.72 ? 199 THR C CG2 1 ATOM 8034 N N . ASN C 2 168 ? 39.747 15.431 -9.856 1.00 49.39 ? 200 ASN C N 1 ATOM 8035 C CA . ASN C 2 168 ? 39.333 15.918 -8.531 1.00 50.24 ? 200 ASN C CA 1 ATOM 8036 C C . ASN C 2 168 ? 38.649 17.283 -8.666 1.00 56.14 ? 200 ASN C C 1 ATOM 8037 O O . ASN C 2 168 ? 39.117 18.278 -8.112 1.00 58.43 ? 200 ASN C O 1 ATOM 8038 C CB . ASN C 2 168 ? 40.545 16.093 -7.600 1.00 46.80 ? 200 ASN C CB 1 ATOM 8039 C CG . ASN C 2 168 ? 41.119 14.785 -7.118 1.00 44.36 ? 200 ASN C CG 1 ATOM 8040 O OD1 . ASN C 2 168 ? 40.757 14.304 -6.038 1.00 42.04 ? 200 ASN C OD1 1 ATOM 8041 N ND2 . ASN C 2 168 ? 42.028 14.202 -7.908 1.00 43.42 ? 200 ASN C ND2 1 ATOM 8042 N N . PRO C 2 169 ? 37.525 17.342 -9.384 1.00 59.77 ? 201 PRO C N 1 ATOM 8043 C CA . PRO C 2 169 ? 37.017 18.637 -9.896 1.00 59.87 ? 201 PRO C CA 1 ATOM 8044 C C . PRO C 2 169 ? 36.465 19.668 -8.877 1.00 58.68 ? 201 PRO C C 1 ATOM 8045 O O . PRO C 2 169 ? 35.893 20.695 -9.277 1.00 56.90 ? 201 PRO C O 1 ATOM 8046 C CB . PRO C 2 169 ? 35.932 18.212 -10.895 1.00 62.50 ? 201 PRO C CB 1 ATOM 8047 C CG . PRO C 2 169 ? 36.099 16.723 -11.086 1.00 63.17 ? 201 PRO C CG 1 ATOM 8048 C CD . PRO C 2 169 ? 36.681 16.215 -9.804 1.00 60.79 ? 201 PRO C CD 1 ATOM 8049 N N . ASN C 2 170 ? 36.621 19.401 -7.585 1.00 57.70 ? 202 ASN C N 1 ATOM 8050 C CA . ASN C 2 170 ? 36.434 20.440 -6.574 1.00 58.91 ? 202 ASN C CA 1 ATOM 8051 C C . ASN C 2 170 ? 37.780 20.882 -5.973 1.00 60.31 ? 202 ASN C C 1 ATOM 8052 O O . ASN C 2 170 ? 37.828 21.619 -4.982 1.00 68.47 ? 202 ASN C O 1 ATOM 8053 C CB . ASN C 2 170 ? 35.441 19.998 -5.492 1.00 57.25 ? 202 ASN C CB 1 ATOM 8054 C CG . ASN C 2 170 ? 35.819 18.692 -4.843 1.00 57.00 ? 202 ASN C CG 1 ATOM 8055 O OD1 . ASN C 2 170 ? 36.447 17.833 -5.463 1.00 56.19 ? 202 ASN C OD1 1 ATOM 8056 N ND2 . ASN C 2 170 ? 35.424 18.525 -3.589 1.00 58.11 ? 202 ASN C ND2 1 ATOM 8057 N N . LEU C 2 171 ? 38.867 20.422 -6.588 1.00 55.03 ? 203 LEU C N 1 ATOM 8058 C CA . LEU C 2 171 ? 40.198 20.952 -6.349 1.00 48.54 ? 203 LEU C CA 1 ATOM 8059 C C . LEU C 2 171 ? 40.498 21.901 -7.510 1.00 44.11 ? 203 LEU C C 1 ATOM 8060 O O . LEU C 2 171 ? 40.601 21.473 -8.660 1.00 39.21 ? 203 LEU C O 1 ATOM 8061 C CB . LEU C 2 171 ? 41.214 19.800 -6.296 1.00 47.71 ? 203 LEU C CB 1 ATOM 8062 C CG . LEU C 2 171 ? 42.681 20.163 -6.064 1.00 46.91 ? 203 LEU C CG 1 ATOM 8063 C CD1 . LEU C 2 171 ? 42.782 20.883 -4.726 1.00 47.89 ? 203 LEU C CD1 1 ATOM 8064 C CD2 . LEU C 2 171 ? 43.611 18.946 -6.148 1.00 44.18 ? 203 LEU C CD2 1 ATOM 8065 N N . ARG C 2 172 ? 40.595 23.192 -7.233 1.00 42.93 ? 204 ARG C N 1 ATOM 8066 C CA . ARG C 2 172 ? 41.007 24.123 -8.285 1.00 45.30 ? 204 ARG C CA 1 ATOM 8067 C C . ARG C 2 172 ? 42.476 24.529 -8.152 1.00 44.28 ? 204 ARG C C 1 ATOM 8068 O O . ARG C 2 172 ? 42.886 25.051 -7.121 1.00 47.27 ? 204 ARG C O 1 ATOM 8069 C CB . ARG C 2 172 ? 40.133 25.377 -8.309 1.00 45.82 ? 204 ARG C CB 1 ATOM 8070 C CG . ARG C 2 172 ? 40.558 26.388 -9.374 1.00 47.29 ? 204 ARG C CG 1 ATOM 8071 C CD . ARG C 2 172 ? 39.730 27.650 -9.267 1.00 50.74 ? 204 ARG C CD 1 ATOM 8072 N NE . ARG C 2 172 ? 38.305 27.344 -9.377 1.00 50.22 ? 204 ARG C NE 1 ATOM 8073 C CZ . ARG C 2 172 ? 37.655 27.171 -10.524 1.00 47.50 ? 204 ARG C CZ 1 ATOM 8074 N NH1 . ARG C 2 172 ? 38.281 27.272 -11.702 1.00 47.20 1 204 ARG C NH1 1 ATOM 8075 N NH2 . ARG C 2 172 ? 36.368 26.875 -10.488 1.00 45.10 ? 204 ARG C NH2 1 ATOM 8076 N N . ILE C 2 173 ? 43.250 24.308 -9.211 1.00 41.65 ? 205 ILE C N 1 ATOM 8077 C CA . ILE C 2 173 ? 44.595 24.862 -9.320 1.00 40.26 ? 205 ILE C CA 1 ATOM 8078 C C . ILE C 2 173 ? 44.516 26.330 -9.793 1.00 40.45 ? 205 ILE C C 1 ATOM 8079 O O . ILE C 2 173 ? 43.948 26.601 -10.855 1.00 41.81 ? 205 ILE C O 1 ATOM 8080 C CB . ILE C 2 173 ? 45.440 24.088 -10.350 1.00 39.32 ? 205 ILE C CB 1 ATOM 8081 C CG1 . ILE C 2 173 ? 45.427 22.576 -10.082 1.00 38.45 ? 205 ILE C CG1 1 ATOM 8082 C CG2 . ILE C 2 173 ? 46.857 24.630 -10.357 1.00 38.80 ? 205 ILE C CG2 1 ATOM 8083 C CD1 . ILE C 2 173 ? 45.914 22.187 -8.703 1.00 37.76 ? 205 ILE C CD1 1 ATOM 8084 N N . ILE C 2 174 ? 45.064 27.261 -9.000 1.00 39.24 ? 206 ILE C N 1 ATOM 8085 C CA . ILE C 2 174 ? 45.203 28.687 -9.381 1.00 39.14 ? 206 ILE C CA 1 ATOM 8086 C C . ILE C 2 174 ? 46.659 28.966 -9.792 1.00 37.12 ? 206 ILE C C 1 ATOM 8087 O O . ILE C 2 174 ? 47.504 29.143 -8.923 1.00 37.67 ? 206 ILE C O 1 ATOM 8088 C CB . ILE C 2 174 ? 44.814 29.668 -8.218 1.00 40.00 ? 206 ILE C CB 1 ATOM 8089 C CG1 . ILE C 2 174 ? 43.357 29.465 -7.796 1.00 40.46 ? 206 ILE C CG1 1 ATOM 8090 C CG2 . ILE C 2 174 ? 45.049 31.146 -8.601 1.00 39.62 ? 206 ILE C CG2 1 ATOM 8091 C CD1 . ILE C 2 174 ? 42.903 30.391 -6.688 1.00 40.06 ? 206 ILE C CD1 1 ATOM 8092 N N . SER C 2 175 ? 46.949 29.006 -11.094 1.00 34.58 ? 207 SER C N 1 ATOM 8093 C CA . SER C 2 175 ? 48.284 29.342 -11.581 1.00 34.53 ? 207 SER C CA 1 ATOM 8094 C C . SER C 2 175 ? 48.457 30.875 -11.677 1.00 37.17 ? 207 SER C C 1 ATOM 8095 O O . SER C 2 175 ? 47.748 31.558 -12.416 1.00 39.21 ? 207 SER C O 1 ATOM 8096 C CB . SER C 2 175 ? 48.559 28.643 -12.922 1.00 35.31 ? 207 SER C CB 1 ATOM 8097 O OG . SER C 2 175 ? 49.757 29.095 -13.557 1.00 35.46 ? 207 SER C OG 1 ATOM 8098 N N . LEU C 2 176 ? 49.397 31.407 -10.896 1.00 39.87 ? 208 LEU C N 1 ATOM 8099 C CA . LEU C 2 176 ? 49.709 32.839 -10.874 1.00 40.45 ? 208 LEU C CA 1 ATOM 8100 C C . LEU C 2 176 ? 50.960 33.182 -11.708 1.00 43.49 ? 208 LEU C C 1 ATOM 8101 O O . LEU C 2 176 ? 51.961 32.406 -11.793 1.00 44.77 ? 208 LEU C O 1 ATOM 8102 C CB . LEU C 2 176 ? 49.893 33.342 -9.429 1.00 38.72 ? 208 LEU C CB 1 ATOM 8103 C CG . LEU C 2 176 ? 48.628 33.421 -8.578 1.00 40.46 ? 208 LEU C CG 1 ATOM 8104 C CD1 . LEU C 2 176 ? 48.977 33.586 -7.108 1.00 39.65 ? 208 LEU C CD1 1 ATOM 8105 C CD2 . LEU C 2 176 ? 47.722 34.553 -9.052 1.00 41.05 ? 208 LEU C CD2 1 ATOM 8106 N N . ASN C 2 177 ? 50.888 34.358 -12.326 1.00 41.20 ? 209 ASN C N 1 ATOM 8107 C CA . ASN C 2 177 ? 52.025 34.940 -12.975 1.00 39.01 ? 209 ASN C CA 1 ATOM 8108 C C . ASN C 2 177 ? 52.555 35.973 -12.017 1.00 36.46 ? 209 ASN C C 1 ATOM 8109 O O . ASN C 2 177 ? 52.140 37.125 -12.013 1.00 34.86 ? 209 ASN C O 1 ATOM 8110 C CB . ASN C 2 177 ? 51.608 35.537 -14.299 1.00 40.58 ? 209 ASN C CB 1 ATOM 8111 C CG . ASN C 2 177 ? 52.777 35.796 -15.195 1.00 42.09 ? 209 ASN C CG 1 ATOM 8112 O OD1 . ASN C 2 177 ? 53.736 35.023 -15.205 1.00 43.40 ? 209 ASN C OD1 1 ATOM 8113 N ND2 . ASN C 2 177 ? 52.711 36.884 -15.961 1.00 42.70 ? 209 ASN C ND2 1 ATOM 8114 N N . THR C 2 178 ? 53.435 35.516 -11.140 1.00 36.17 ? 210 THR C N 1 ATOM 8115 C CA . THR C 2 178 ? 53.988 36.368 -10.099 1.00 36.69 ? 210 THR C CA 1 ATOM 8116 C C . THR C 2 178 ? 55.228 37.095 -10.632 1.00 37.80 ? 210 THR C C 1 ATOM 8117 O O . THR C 2 178 ? 55.740 38.002 -9.962 1.00 37.96 ? 210 THR C O 1 ATOM 8118 C CB . THR C 2 178 ? 54.305 35.580 -8.795 1.00 37.02 ? 210 THR C CB 1 ATOM 8119 O OG1 . THR C 2 178 ? 54.868 34.300 -9.111 1.00 38.59 ? 210 THR C OG1 1 ATOM 8120 C CG2 . THR C 2 178 ? 53.038 35.342 -7.957 1.00 37.22 ? 210 THR C CG2 1 ATOM 8121 N N . ASN C 2 179 ? 55.682 36.726 -11.848 1.00 36.73 ? 211 ASN C N 1 ATOM 8122 C CA . ASN C 2 179 ? 56.792 37.426 -12.533 1.00 34.19 ? 211 ASN C CA 1 ATOM 8123 C C . ASN C 2 179 ? 56.387 38.834 -12.884 1.00 34.91 ? 211 ASN C C 1 ATOM 8124 O O . ASN C 2 179 ? 57.241 39.670 -13.205 1.00 32.84 ? 211 ASN C O 1 ATOM 8125 C CB . ASN C 2 179 ? 57.213 36.734 -13.821 1.00 32.35 ? 211 ASN C CB 1 ATOM 8126 C CG . ASN C 2 179 ? 57.389 35.253 -13.660 1.00 31.15 ? 211 ASN C CG 1 ATOM 8127 O OD1 . ASN C 2 179 ? 56.663 34.477 -14.263 1.00 29.56 ? 211 ASN C OD1 1 ATOM 8128 N ND2 . ASN C 2 179 ? 58.349 34.848 -12.844 1.00 31.03 ? 211 ASN C ND2 1 ATOM 8129 N N . LEU C 2 180 ? 55.068 39.056 -12.861 1.00 36.73 ? 212 LEU C N 1 ATOM 8130 C CA . LEU C 2 180 ? 54.477 40.396 -12.855 1.00 39.50 ? 212 LEU C CA 1 ATOM 8131 C C . LEU C 2 180 ? 54.962 41.198 -11.647 1.00 39.49 ? 212 LEU C C 1 ATOM 8132 O O . LEU C 2 180 ? 54.928 42.440 -11.666 1.00 42.35 ? 212 LEU C O 1 ATOM 8133 C CB . LEU C 2 180 ? 52.932 40.334 -12.858 1.00 40.15 ? 212 LEU C CB 1 ATOM 8134 C CG . LEU C 2 180 ? 52.253 39.621 -14.053 1.00 42.90 ? 212 LEU C CG 1 ATOM 8135 C CD1 . LEU C 2 180 ? 50.737 39.710 -13.956 1.00 43.48 ? 212 LEU C CD1 1 ATOM 8136 C CD2 . LEU C 2 180 ? 52.699 40.128 -15.422 1.00 43.03 ? 212 LEU C CD2 1 ATOM 8137 N N . TYR C 2 181 ? 55.427 40.492 -10.615 1.00 35.05 ? 213 TYR C N 1 ATOM 8138 C CA . TYR C 2 181 ? 55.722 41.094 -9.355 1.00 32.37 ? 213 TYR C CA 1 ATOM 8139 C C . TYR C 2 181 ? 57.201 41.096 -9.045 1.00 28.62 ? 213 TYR C C 1 ATOM 8140 O O . TYR C 2 181 ? 57.631 41.667 -8.057 1.00 27.00 ? 213 TYR C O 1 ATOM 8141 C CB . TYR C 2 181 ? 54.922 40.352 -8.293 1.00 36.52 ? 213 TYR C CB 1 ATOM 8142 C CG . TYR C 2 181 ? 53.417 40.327 -8.575 1.00 41.62 ? 213 TYR C CG 1 ATOM 8143 C CD1 . TYR C 2 181 ? 52.738 41.493 -8.948 1.00 44.64 ? 213 TYR C CD1 1 ATOM 8144 C CD2 . TYR C 2 181 ? 52.665 39.159 -8.449 1.00 43.23 ? 213 TYR C CD2 1 ATOM 8145 C CE1 . TYR C 2 181 ? 51.378 41.493 -9.197 1.00 44.80 ? 213 TYR C CE1 1 ATOM 8146 C CE2 . TYR C 2 181 ? 51.294 39.161 -8.701 1.00 44.19 ? 213 TYR C CE2 1 ATOM 8147 C CZ . TYR C 2 181 ? 50.667 40.343 -9.075 1.00 45.04 ? 213 TYR C CZ 1 ATOM 8148 O OH . TYR C 2 181 ? 49.331 40.439 -9.347 1.00 47.06 ? 213 TYR C OH 1 ATOM 8149 N N . TYR C 2 182 ? 57.990 40.508 -9.922 1.00 26.56 ? 214 TYR C N 1 ATOM 8150 C CA . TYR C 2 182 ? 59.412 40.359 -9.679 1.00 27.00 ? 214 TYR C CA 1 ATOM 8151 C C . TYR C 2 182 ? 60.132 41.662 -9.911 1.00 28.02 ? 214 TYR C C 1 ATOM 8152 O O . TYR C 2 182 ? 59.810 42.383 -10.837 1.00 25.53 ? 214 TYR C O 1 ATOM 8153 C CB . TYR C 2 182 ? 59.945 39.333 -10.656 1.00 27.79 ? 214 TYR C CB 1 ATOM 8154 C CG . TYR C 2 182 ? 61.365 38.841 -10.475 1.00 26.83 ? 214 TYR C CG 1 ATOM 8155 C CD1 . TYR C 2 182 ? 61.927 38.680 -9.212 1.00 26.12 ? 214 TYR C CD1 1 ATOM 8156 C CD2 . TYR C 2 182 ? 62.112 38.452 -11.594 1.00 26.08 ? 214 TYR C CD2 1 ATOM 8157 C CE1 . TYR C 2 182 ? 63.208 38.190 -9.074 1.00 26.36 ? 214 TYR C CE1 1 ATOM 8158 C CE2 . TYR C 2 182 ? 63.393 37.970 -11.464 1.00 25.92 ? 214 TYR C CE2 1 ATOM 8159 C CZ . TYR C 2 182 ? 63.937 37.838 -10.206 1.00 26.19 ? 214 TYR C CZ 1 ATOM 8160 O OH . TYR C 2 182 ? 65.215 37.342 -10.084 1.00 26.45 ? 214 TYR C OH 1 ATOM 8161 N N . GLY C 2 183 ? 61.123 41.943 -9.070 1.00 32.09 ? 215 GLY C N 1 ATOM 8162 C CA . GLY C 2 183 ? 61.868 43.208 -9.093 1.00 34.76 ? 215 GLY C CA 1 ATOM 8163 C C . GLY C 2 183 ? 62.262 43.685 -10.483 1.00 38.75 ? 215 GLY C C 1 ATOM 8164 O O . GLY C 2 183 ? 61.786 44.743 -10.913 1.00 40.19 ? 215 GLY C O 1 ATOM 8165 N N . PRO C 2 184 ? 63.103 42.898 -11.215 1.00 41.49 ? 216 PRO C N 1 ATOM 8166 C CA . PRO C 2 184 ? 63.620 43.279 -12.559 1.00 40.71 ? 216 PRO C CA 1 ATOM 8167 C C . PRO C 2 184 ? 62.616 43.464 -13.700 1.00 42.34 ? 216 PRO C C 1 ATOM 8168 O O . PRO C 2 184 ? 63.064 43.709 -14.822 1.00 45.07 ? 216 PRO C O 1 ATOM 8169 C CB . PRO C 2 184 ? 64.553 42.123 -12.942 1.00 40.12 ? 216 PRO C CB 1 ATOM 8170 C CG . PRO C 2 184 ? 64.850 41.409 -11.674 1.00 41.47 ? 216 PRO C CG 1 ATOM 8171 C CD . PRO C 2 184 ? 63.675 41.617 -10.755 1.00 41.74 ? 216 PRO C CD 1 ATOM 8172 N N . ASN C 2 185 ? 61.306 43.331 -13.453 1.00 43.45 ? 217 ASN C N 1 ATOM 8173 C CA . ASN C 2 185 ? 60.295 43.482 -14.516 1.00 44.73 ? 217 ASN C CA 1 ATOM 8174 C C . ASN C 2 185 ? 59.921 44.931 -14.774 1.00 48.65 ? 217 ASN C C 1 ATOM 8175 O O . ASN C 2 185 ? 59.041 45.472 -14.104 1.00 49.66 ? 217 ASN C O 1 ATOM 8176 C CB . ASN C 2 185 ? 59.025 42.684 -14.211 1.00 44.54 ? 217 ASN C CB 1 ATOM 8177 C CG . ASN C 2 185 ? 58.107 42.567 -15.418 1.00 44.90 ? 217 ASN C CG 1 ATOM 8178 O OD1 . ASN C 2 185 ? 58.357 43.170 -16.465 1.00 46.74 ? 217 ASN C OD1 1 ATOM 8179 N ND2 . ASN C 2 185 ? 57.052 41.770 -15.286 1.00 43.90 ? 217 ASN C ND2 1 ATOM 8180 N N . ILE C 2 186 ? 60.557 45.531 -15.781 1.00 52.77 ? 218 ILE C N 1 ATOM 8181 C CA . ILE C 2 186 ? 60.384 46.951 -16.077 1.00 56.15 ? 218 ILE C CA 1 ATOM 8182 C C . ILE C 2 186 ? 58.939 47.291 -16.496 1.00 57.71 ? 218 ILE C C 1 ATOM 8183 O O . ILE C 2 186 ? 58.498 48.427 -16.262 1.00 58.44 ? 218 ILE C O 1 ATOM 8184 C CB . ILE C 2 186 ? 61.382 47.445 -17.158 1.00 58.33 ? 218 ILE C CB 1 ATOM 8185 C CG1 . ILE C 2 186 ? 62.843 47.231 -16.715 1.00 61.67 ? 218 ILE C CG1 1 ATOM 8186 C CG2 . ILE C 2 186 ? 61.146 48.920 -17.473 1.00 58.66 ? 218 ILE C CG2 1 ATOM 8187 C CD1 . ILE C 2 186 ? 63.367 48.243 -15.700 1.00 64.99 ? 218 ILE C CD1 1 ATOM 8188 N N . MET C 2 187 ? 58.221 46.309 -17.075 1.00 55.01 ? 219 MET C N 1 ATOM 8189 C CA . MET C 2 187 ? 56.850 46.484 -17.631 1.00 52.83 ? 219 MET C CA 1 ATOM 8190 C C . MET C 2 187 ? 55.773 46.849 -16.599 1.00 50.70 ? 219 MET C C 1 ATOM 8191 O O . MET C 2 187 ? 54.771 47.497 -16.929 1.00 48.91 ? 219 MET C O 1 ATOM 8192 C CB . MET C 2 187 ? 56.380 45.192 -18.318 1.00 55.09 ? 219 MET C CB 1 ATOM 8193 C CG . MET C 2 187 ? 57.226 44.674 -19.471 1.00 56.03 ? 219 MET C CG 1 ATOM 8194 S SD . MET C 2 187 ? 57.131 45.725 -20.921 1.00 58.04 ? 219 MET C SD 1 ATOM 8195 C CE . MET C 2 187 ? 58.617 46.722 -20.735 1.00 62.34 ? 219 MET C CE 1 ATOM 8196 N N . THR C 2 188 ? 55.983 46.418 -15.360 1.00 50.36 ? 220 THR C N 1 ATOM 8197 C CA . THR C 2 188 ? 55.000 46.568 -14.294 1.00 51.99 ? 220 THR C CA 1 ATOM 8198 C C . THR C 2 188 ? 55.284 47.680 -13.262 1.00 52.07 ? 220 THR C C 1 ATOM 8199 O O . THR C 2 188 ? 54.555 47.799 -12.278 1.00 51.36 ? 220 THR C O 1 ATOM 8200 C CB . THR C 2 188 ? 54.876 45.232 -13.520 1.00 55.62 ? 220 THR C CB 1 ATOM 8201 O OG1 . THR C 2 188 ? 56.117 44.929 -12.852 1.00 51.62 ? 220 THR C OG1 1 ATOM 8202 C CG2 . THR C 2 188 ? 54.477 44.083 -14.481 1.00 57.07 ? 220 THR C CG2 1 ATOM 8203 N N . LEU C 2 189 ? 56.323 48.485 -13.462 1.00 52.18 ? 221 LEU C N 1 ATOM 8204 C CA . LEU C 2 189 ? 56.705 49.489 -12.463 1.00 51.69 ? 221 LEU C CA 1 ATOM 8205 C C . LEU C 2 189 ? 55.579 50.485 -12.232 1.00 54.51 ? 221 LEU C C 1 ATOM 8206 O O . LEU C 2 189 ? 54.880 50.876 -13.174 1.00 56.75 ? 221 LEU C O 1 ATOM 8207 C CB . LEU C 2 189 ? 57.962 50.235 -12.895 1.00 52.71 ? 221 LEU C CB 1 ATOM 8208 C CG . LEU C 2 189 ? 59.305 49.632 -12.468 1.00 52.81 ? 221 LEU C CG 1 ATOM 8209 C CD1 . LEU C 2 189 ? 60.377 49.831 -13.535 1.00 54.15 ? 221 LEU C CD1 1 ATOM 8210 C CD2 . LEU C 2 189 ? 59.737 50.249 -11.152 1.00 51.05 ? 221 LEU C CD2 1 ATOM 8211 N N . ASN C 2 190 ? 55.406 50.869 -10.971 1.00 55.42 ? 222 ASN C N 1 ATOM 8212 C CA . ASN C 2 190 ? 54.364 51.818 -10.536 1.00 57.18 ? 222 ASN C CA 1 ATOM 8213 C C . ASN C 2 190 ? 52.893 51.431 -10.842 1.00 54.27 ? 222 ASN C C 1 ATOM 8214 O O . ASN C 2 190 ? 52.022 52.292 -10.782 1.00 53.87 ? 222 ASN C O 1 ATOM 8215 C CB . ASN C 2 190 ? 54.685 53.254 -11.043 1.00 57.96 ? 222 ASN C CB 1 ATOM 8216 C CG . ASN C 2 190 ? 54.251 54.362 -10.051 1.00 60.42 ? 222 ASN C CG 1 ATOM 8217 O OD1 . ASN C 2 190 ? 54.332 54.205 -8.816 1.00 56.39 ? 222 ASN C OD1 1 ATOM 8218 N ND2 . ASN C 2 190 ? 53.798 55.498 -10.596 1.00 59.53 ? 222 ASN C ND2 1 ATOM 8219 N N . LYS C 2 191 ? 52.611 50.150 -11.118 1.00 56.50 ? 223 LYS C N 1 ATOM 8220 C CA . LYS C 2 191 ? 51.225 49.673 -11.373 1.00 58.34 ? 223 LYS C CA 1 ATOM 8221 C C . LYS C 2 191 ? 50.565 49.089 -10.127 1.00 57.68 ? 223 LYS C C 1 ATOM 8222 O O . LYS C 2 191 ? 51.000 48.070 -9.599 1.00 51.50 ? 223 LYS C O 1 ATOM 8223 C CB . LYS C 2 191 ? 51.163 48.613 -12.485 1.00 59.34 ? 223 LYS C CB 1 ATOM 8224 C CG . LYS C 2 191 ? 51.628 49.094 -13.851 1.00 61.81 ? 223 LYS C CG 1 ATOM 8225 C CD . LYS C 2 191 ? 50.959 48.362 -15.017 1.00 63.38 ? 223 LYS C CD 1 ATOM 8226 C CE . LYS C 2 191 ? 51.826 48.460 -16.271 1.00 65.04 ? 223 LYS C CE 1 ATOM 8227 N NZ . LYS C 2 191 ? 51.068 48.641 -17.532 1.00 65.15 1 223 LYS C NZ 1 ATOM 8228 N N . THR C 2 192 ? 49.509 49.760 -9.676 1.00 64.48 ? 224 THR C N 1 ATOM 8229 C CA . THR C 2 192 ? 48.639 49.286 -8.589 1.00 66.12 ? 224 THR C CA 1 ATOM 8230 C C . THR C 2 192 ? 48.321 47.793 -8.620 1.00 65.78 ? 224 THR C C 1 ATOM 8231 O O . THR C 2 192 ? 48.342 47.136 -7.573 1.00 63.06 ? 224 THR C O 1 ATOM 8232 C CB . THR C 2 192 ? 47.269 50.017 -8.586 1.00 68.42 ? 224 THR C CB 1 ATOM 8233 O OG1 . THR C 2 192 ? 46.387 49.346 -7.681 1.00 69.91 ? 224 THR C OG1 1 ATOM 8234 C CG2 . THR C 2 192 ? 46.593 50.046 -9.990 1.00 67.17 ? 224 THR C CG2 1 ATOM 8235 N N . ASP C 2 193 ? 47.996 47.283 -9.814 1.00 64.73 ? 225 ASP C N 1 ATOM 8236 C CA . ASP C 2 193 ? 47.602 45.876 -10.003 1.00 61.37 ? 225 ASP C CA 1 ATOM 8237 C C . ASP C 2 193 ? 47.873 45.420 -11.440 1.00 56.25 ? 225 ASP C C 1 ATOM 8238 O O . ASP C 2 193 ? 47.024 45.618 -12.307 1.00 53.80 ? 225 ASP C O 1 ATOM 8239 C CB . ASP C 2 193 ? 46.113 45.669 -9.665 1.00 60.25 ? 225 ASP C CB 1 ATOM 8240 C CG . ASP C 2 193 ? 45.655 44.215 -9.839 1.00 58.89 ? 225 ASP C CG 1 ATOM 8241 O OD1 . ASP C 2 193 ? 46.516 43.304 -9.925 1.00 57.09 ? 225 ASP C OD1 1 ATOM 8242 O OD2 . ASP C 2 193 ? 44.426 43.984 -9.888 1.00 58.89 -1 225 ASP C OD2 1 ATOM 8243 N N . PRO C 2 194 ? 49.046 44.793 -11.689 1.00 52.07 ? 226 PRO C N 1 ATOM 8244 C CA . PRO C 2 194 ? 49.374 44.329 -13.035 1.00 50.68 ? 226 PRO C CA 1 ATOM 8245 C C . PRO C 2 194 ? 48.522 43.141 -13.491 1.00 47.81 ? 226 PRO C C 1 ATOM 8246 O O . PRO C 2 194 ? 48.309 42.182 -12.737 1.00 43.91 ? 226 PRO C O 1 ATOM 8247 C CB . PRO C 2 194 ? 50.865 43.949 -12.962 1.00 50.37 ? 226 PRO C CB 1 ATOM 8248 C CG . PRO C 2 194 ? 51.290 44.130 -11.568 1.00 50.57 ? 226 PRO C CG 1 ATOM 8249 C CD . PRO C 2 194 ? 50.107 44.488 -10.721 1.00 51.87 ? 226 PRO C CD 1 ATOM 8250 N N . ALA C 2 195 ? 48.060 43.252 -14.735 1.00 46.79 ? 227 ALA C N 1 ATOM 8251 C CA . ALA C 2 195 ? 47.184 42.290 -15.397 1.00 45.84 ? 227 ALA C CA 1 ATOM 8252 C C . ALA C 2 195 ? 45.846 42.121 -14.681 1.00 43.46 ? 227 ALA C C 1 ATOM 8253 O O . ALA C 2 195 ? 45.103 41.187 -14.972 1.00 38.24 ? 227 ALA C O 1 ATOM 8254 C CB . ALA C 2 195 ? 47.895 40.956 -15.592 1.00 46.54 ? 227 ALA C CB 1 ATOM 8255 N N . ASN C 2 196 ? 45.533 43.062 -13.790 1.00 44.47 ? 228 ASN C N 1 ATOM 8256 C CA . ASN C 2 196 ? 44.364 42.980 -12.945 1.00 50.11 ? 228 ASN C CA 1 ATOM 8257 C C . ASN C 2 196 ? 44.307 41.646 -12.190 1.00 52.37 ? 228 ASN C C 1 ATOM 8258 O O . ASN C 2 196 ? 43.231 41.069 -11.992 1.00 55.08 ? 228 ASN C O 1 ATOM 8259 C CB . ASN C 2 196 ? 43.100 43.198 -13.788 1.00 55.86 ? 228 ASN C CB 1 ATOM 8260 C CG . ASN C 2 196 ? 42.767 44.666 -13.980 1.00 61.80 ? 228 ASN C CG 1 ATOM 8261 O OD1 . ASN C 2 196 ? 43.426 45.369 -14.742 1.00 66.93 ? 228 ASN C OD1 1 ATOM 8262 N ND2 . ASN C 2 196 ? 41.726 45.135 -13.295 1.00 67.69 ? 228 ASN C ND2 1 ATOM 8263 N N . GLN C 2 197 ? 45.470 41.159 -11.757 1.00 54.47 ? 229 GLN C N 1 ATOM 8264 C CA . GLN C 2 197 ? 45.590 39.793 -11.208 1.00 52.57 ? 229 GLN C CA 1 ATOM 8265 C C . GLN C 2 197 ? 45.105 39.659 -9.740 1.00 52.38 ? 229 GLN C C 1 ATOM 8266 O O . GLN C 2 197 ? 44.488 38.646 -9.397 1.00 49.15 ? 229 GLN C O 1 ATOM 8267 C CB . GLN C 2 197 ? 47.020 39.264 -11.389 1.00 49.92 ? 229 GLN C CB 1 ATOM 8268 C CG . GLN C 2 197 ? 47.315 37.989 -10.628 1.00 49.32 ? 229 GLN C CG 1 ATOM 8269 C CD . GLN C 2 197 ? 48.533 37.275 -11.145 1.00 50.16 ? 229 GLN C CD 1 ATOM 8270 O OE1 . GLN C 2 197 ? 49.577 37.228 -10.495 1.00 51.53 ? 229 GLN C OE1 1 ATOM 8271 N NE2 . GLN C 2 197 ? 48.406 36.706 -12.318 1.00 50.74 ? 229 GLN C NE2 1 ATOM 8272 N N . PHE C 2 198 ? 45.365 40.664 -8.895 1.00 52.46 ? 230 PHE C N 1 ATOM 8273 C CA . PHE C 2 198 ? 44.794 40.689 -7.545 1.00 52.85 ? 230 PHE C CA 1 ATOM 8274 C C . PHE C 2 198 ? 43.278 40.770 -7.625 1.00 56.65 ? 230 PHE C C 1 ATOM 8275 O O . PHE C 2 198 ? 42.596 40.128 -6.833 1.00 66.34 ? 230 PHE C O 1 ATOM 8276 C CB . PHE C 2 198 ? 45.269 41.873 -6.703 1.00 53.29 ? 230 PHE C CB 1 ATOM 8277 C CG . PHE C 2 198 ? 46.748 42.034 -6.655 1.00 53.33 ? 230 PHE C CG 1 ATOM 8278 C CD1 . PHE C 2 198 ? 47.553 40.988 -6.300 1.00 54.78 ? 230 PHE C CD1 1 ATOM 8279 C CD2 . PHE C 2 198 ? 47.332 43.248 -6.963 1.00 56.32 ? 230 PHE C CD2 1 ATOM 8280 C CE1 . PHE C 2 198 ? 48.927 41.135 -6.268 1.00 55.37 ? 230 PHE C CE1 1 ATOM 8281 C CE2 . PHE C 2 198 ? 48.702 43.408 -6.930 1.00 55.50 ? 230 PHE C CE2 1 ATOM 8282 C CZ . PHE C 2 198 ? 49.500 42.347 -6.584 1.00 55.30 ? 230 PHE C CZ 1 ATOM 8283 N N . GLU C 2 199 ? 42.744 41.566 -8.551 1.00 53.59 ? 231 GLU C N 1 ATOM 8284 C CA . GLU C 2 199 ? 41.295 41.658 -8.697 1.00 52.30 ? 231 GLU C CA 1 ATOM 8285 C C . GLU C 2 199 ? 40.726 40.284 -9.083 1.00 46.97 ? 231 GLU C C 1 ATOM 8286 O O . GLU C 2 199 ? 39.760 39.832 -8.486 1.00 43.08 ? 231 GLU C O 1 ATOM 8287 C CB . GLU C 2 199 ? 40.911 42.745 -9.708 1.00 58.89 ? 231 GLU C CB 1 ATOM 8288 C CG . GLU C 2 199 ? 39.488 43.282 -9.541 1.00 64.33 ? 231 GLU C CG 1 ATOM 8289 C CD . GLU C 2 199 ? 38.956 44.011 -10.781 1.00 66.91 ? 231 GLU C CD 1 ATOM 8290 O OE1 . GLU C 2 199 ? 38.306 45.063 -10.613 1.00 76.82 ? 231 GLU C OE1 1 ATOM 8291 O OE2 . GLU C 2 199 ? 39.171 43.549 -11.924 1.00 61.65 -1 231 GLU C OE2 1 ATOM 8292 N N . TRP C 2 200 ? 41.360 39.618 -10.052 1.00 47.74 ? 232 TRP C N 1 ATOM 8293 C CA . TRP C 2 200 ? 40.996 38.245 -10.493 1.00 47.91 ? 232 TRP C CA 1 ATOM 8294 C C . TRP C 2 200 ? 41.186 37.149 -9.415 1.00 49.30 ? 232 TRP C C 1 ATOM 8295 O O . TRP C 2 200 ? 40.418 36.188 -9.376 1.00 48.21 ? 232 TRP C O 1 ATOM 8296 C CB . TRP C 2 200 ? 41.798 37.868 -11.760 1.00 46.29 ? 232 TRP C CB 1 ATOM 8297 C CG . TRP C 2 200 ? 41.597 36.452 -12.249 1.00 46.34 ? 232 TRP C CG 1 ATOM 8298 C CD1 . TRP C 2 200 ? 40.614 36.014 -13.077 1.00 45.97 ? 232 TRP C CD1 1 ATOM 8299 C CD2 . TRP C 2 200 ? 42.413 35.296 -11.949 1.00 48.84 ? 232 TRP C CD2 1 ATOM 8300 N NE1 . TRP C 2 200 ? 40.751 34.663 -13.312 1.00 48.32 ? 232 TRP C NE1 1 ATOM 8301 C CE2 . TRP C 2 200 ? 41.846 34.197 -12.632 1.00 48.75 ? 232 TRP C CE2 1 ATOM 8302 C CE3 . TRP C 2 200 ? 43.565 35.088 -11.172 1.00 48.04 ? 232 TRP C CE3 1 ATOM 8303 C CZ2 . TRP C 2 200 ? 42.391 32.904 -12.565 1.00 47.07 ? 232 TRP C CZ2 1 ATOM 8304 C CZ3 . TRP C 2 200 ? 44.110 33.801 -11.115 1.00 48.38 ? 232 TRP C CZ3 1 ATOM 8305 C CH2 . TRP C 2 200 ? 43.520 32.731 -11.812 1.00 46.89 ? 232 TRP C CH2 1 ATOM 8306 N N . LEU C 2 201 ? 42.215 37.275 -8.571 1.00 50.71 ? 233 LEU C N 1 ATOM 8307 C CA . LEU C 2 201 ? 42.443 36.334 -7.449 1.00 50.79 ? 233 LEU C CA 1 ATOM 8308 C C . LEU C 2 201 ? 41.325 36.479 -6.412 1.00 55.30 ? 233 LEU C C 1 ATOM 8309 O O . LEU C 2 201 ? 40.633 35.505 -6.108 1.00 59.19 ? 233 LEU C O 1 ATOM 8310 C CB . LEU C 2 201 ? 43.820 36.573 -6.793 1.00 46.96 ? 233 LEU C CB 1 ATOM 8311 C CG . LEU C 2 201 ? 44.509 35.546 -5.881 1.00 41.74 ? 233 LEU C CG 1 ATOM 8312 C CD1 . LEU C 2 201 ? 44.515 34.144 -6.467 1.00 41.92 ? 233 LEU C CD1 1 ATOM 8313 C CD2 . LEU C 2 201 ? 45.936 36.008 -5.649 1.00 38.97 ? 233 LEU C CD2 1 ATOM 8314 N N . GLU C 2 202 ? 41.145 37.697 -5.889 1.00 59.03 ? 234 GLU C N 1 ATOM 8315 C CA . GLU C 2 202 ? 40.025 38.023 -4.973 1.00 59.20 ? 234 GLU C CA 1 ATOM 8316 C C . GLU C 2 202 ? 38.692 37.508 -5.511 1.00 55.14 ? 234 GLU C C 1 ATOM 8317 O O . GLU C 2 202 ? 37.908 36.938 -4.762 1.00 53.23 ? 234 GLU C O 1 ATOM 8318 C CB . GLU C 2 202 ? 39.943 39.536 -4.708 1.00 61.16 ? 234 GLU C CB 1 ATOM 8319 C CG . GLU C 2 202 ? 40.813 40.001 -3.548 1.00 65.35 ? 234 GLU C CG 1 ATOM 8320 C CD . GLU C 2 202 ? 41.303 41.439 -3.673 1.00 68.98 ? 234 GLU C CD 1 ATOM 8321 O OE1 . GLU C 2 202 ? 41.675 41.887 -4.786 1.00 65.81 ? 234 GLU C OE1 1 ATOM 8322 O OE2 . GLU C 2 202 ? 41.345 42.120 -2.626 1.00 74.17 -1 234 GLU C OE2 1 ATOM 8323 N N . SER C 2 203 ? 38.465 37.712 -6.813 1.00 52.16 ? 235 SER C N 1 ATOM 8324 C CA . SER C 2 203 ? 37.332 37.123 -7.539 1.00 50.51 ? 235 SER C CA 1 ATOM 8325 C C . SER C 2 203 ? 37.337 35.582 -7.521 1.00 52.39 ? 235 SER C C 1 ATOM 8326 O O . SER C 2 203 ? 36.347 34.993 -7.076 1.00 53.66 ? 235 SER C O 1 ATOM 8327 C CB . SER C 2 203 ? 37.284 37.640 -8.990 1.00 47.75 ? 235 SER C CB 1 ATOM 8328 O OG . SER C 2 203 ? 36.402 36.885 -9.809 1.00 43.70 ? 235 SER C OG 1 ATOM 8329 N N . THR C 2 204 ? 38.424 34.942 -7.991 1.00 52.35 ? 236 THR C N 1 ATOM 8330 C CA . THR C 2 204 ? 38.459 33.466 -8.159 1.00 51.74 ? 236 THR C CA 1 ATOM 8331 C C . THR C 2 204 ? 38.362 32.738 -6.800 1.00 52.13 ? 236 THR C C 1 ATOM 8332 O O . THR C 2 204 ? 37.706 31.694 -6.708 1.00 55.82 ? 236 THR C O 1 ATOM 8333 C CB . THR C 2 204 ? 39.709 32.928 -8.943 1.00 52.04 ? 236 THR C CB 1 ATOM 8334 O OG1 . THR C 2 204 ? 39.964 33.690 -10.134 1.00 50.04 ? 236 THR C OG1 1 ATOM 8335 C CG2 . THR C 2 204 ? 39.501 31.469 -9.354 1.00 52.50 ? 236 THR C CG2 1 ATOM 8336 N N . LEU C 2 205 ? 39.002 33.286 -5.758 1.00 50.82 ? 237 LEU C N 1 ATOM 8337 C CA . LEU C 2 205 ? 38.997 32.681 -4.409 1.00 48.70 ? 237 LEU C CA 1 ATOM 8338 C C . LEU C 2 205 ? 37.612 32.811 -3.781 1.00 51.98 ? 237 LEU C C 1 ATOM 8339 O O . LEU C 2 205 ? 37.047 31.829 -3.298 1.00 53.57 ? 237 LEU C O 1 ATOM 8340 C CB . LEU C 2 205 ? 40.049 33.336 -3.492 1.00 45.23 ? 237 LEU C CB 1 ATOM 8341 C CG . LEU C 2 205 ? 41.528 33.096 -3.815 1.00 41.41 ? 237 LEU C CG 1 ATOM 8342 C CD1 . LEU C 2 205 ? 42.375 34.108 -3.073 1.00 39.95 ? 237 LEU C CD1 1 ATOM 8343 C CD2 . LEU C 2 205 ? 41.947 31.677 -3.473 1.00 40.85 ? 237 LEU C CD2 1 ATOM 8344 N N . ASN C 2 206 ? 37.076 34.033 -3.799 1.00 55.58 ? 238 ASN C N 1 ATOM 8345 C CA . ASN C 2 206 ? 35.711 34.319 -3.330 1.00 55.30 ? 238 ASN C CA 1 ATOM 8346 C C . ASN C 2 206 ? 34.681 33.394 -3.980 1.00 56.09 ? 238 ASN C C 1 ATOM 8347 O O . ASN C 2 206 ? 33.763 32.911 -3.321 1.00 57.98 ? 238 ASN C O 1 ATOM 8348 C CB . ASN C 2 206 ? 35.358 35.775 -3.622 1.00 53.89 ? 238 ASN C CB 1 ATOM 8349 C CG . ASN C 2 206 ? 34.278 36.334 -2.719 1.00 57.33 ? 238 ASN C CG 1 ATOM 8350 O OD1 . ASN C 2 206 ? 33.854 37.468 -2.931 1.00 64.92 ? 238 ASN C OD1 1 ATOM 8351 N ND2 . ASN C 2 206 ? 33.841 35.582 -1.704 1.00 57.51 ? 238 ASN C ND2 1 ATOM 8352 N N . ASN C 2 207 ? 34.853 33.154 -5.276 1.00 56.14 ? 239 ASN C N 1 ATOM 8353 C CA . ASN C 2 207 ? 34.120 32.117 -5.981 1.00 57.16 ? 239 ASN C CA 1 ATOM 8354 C C . ASN C 2 207 ? 34.299 30.745 -5.295 1.00 58.51 ? 239 ASN C C 1 ATOM 8355 O O . ASN C 2 207 ? 33.315 30.154 -4.853 1.00 70.42 ? 239 ASN C O 1 ATOM 8356 C CB . ASN C 2 207 ? 34.559 32.063 -7.454 1.00 59.54 ? 239 ASN C CB 1 ATOM 8357 C CG . ASN C 2 207 ? 33.496 31.480 -8.387 1.00 63.49 ? 239 ASN C CG 1 ATOM 8358 O OD1 . ASN C 2 207 ? 32.667 30.648 -7.995 1.00 67.38 ? 239 ASN C OD1 1 ATOM 8359 N ND2 . ASN C 2 207 ? 33.530 31.911 -9.647 1.00 63.81 ? 239 ASN C ND2 1 ATOM 8360 N N . SER C 2 208 ? 35.530 30.249 -5.169 1.00 54.39 ? 240 SER C N 1 ATOM 8361 C CA . SER C 2 208 ? 35.761 28.905 -4.598 1.00 51.13 ? 240 SER C CA 1 ATOM 8362 C C . SER C 2 208 ? 35.286 28.764 -3.136 1.00 53.04 ? 240 SER C C 1 ATOM 8363 O O . SER C 2 208 ? 34.943 27.664 -2.684 1.00 51.18 ? 240 SER C O 1 ATOM 8364 C CB . SER C 2 208 ? 37.241 28.520 -4.712 1.00 49.89 ? 240 SER C CB 1 ATOM 8365 O OG . SER C 2 208 ? 37.654 28.394 -6.069 1.00 46.67 ? 240 SER C OG 1 ATOM 8366 N N . GLN C 2 209 ? 35.248 29.881 -2.410 1.00 56.99 ? 241 GLN C N 1 ATOM 8367 C CA . GLN C 2 209 ? 34.820 29.895 -1.005 1.00 61.13 ? 241 GLN C CA 1 ATOM 8368 C C . GLN C 2 209 ? 33.411 29.415 -0.809 1.00 64.62 ? 241 GLN C C 1 ATOM 8369 O O . GLN C 2 209 ? 33.112 28.801 0.208 1.00 67.23 ? 241 GLN C O 1 ATOM 8370 C CB . GLN C 2 209 ? 34.912 31.304 -0.421 1.00 61.61 ? 241 GLN C CB 1 ATOM 8371 C CG . GLN C 2 209 ? 34.594 31.366 1.065 1.00 60.51 ? 241 GLN C CG 1 ATOM 8372 C CD . GLN C 2 209 ? 35.577 32.219 1.843 1.00 62.18 ? 241 GLN C CD 1 ATOM 8373 O OE1 . GLN C 2 209 ? 36.565 32.729 1.301 1.00 57.17 ? 241 GLN C OE1 1 ATOM 8374 N NE2 . GLN C 2 209 ? 35.318 32.364 3.140 1.00 66.50 ? 241 GLN C NE2 1 ATOM 8375 N N . GLN C 2 210 ? 32.554 29.723 -1.778 1.00 73.33 ? 242 GLN C N 1 ATOM 8376 C CA . GLN C 2 210 ? 31.128 29.404 -1.714 1.00 79.15 ? 242 GLN C CA 1 ATOM 8377 C C . GLN C 2 210 ? 30.726 28.099 -2.396 1.00 81.06 ? 242 GLN C C 1 ATOM 8378 O O . GLN C 2 210 ? 29.625 27.605 -2.159 1.00 91.74 ? 242 GLN C O 1 ATOM 8379 C CB . GLN C 2 210 ? 30.328 30.546 -2.320 1.00 79.58 ? 242 GLN C CB 1 ATOM 8380 C CG . GLN C 2 210 ? 30.387 31.806 -1.476 1.00 84.08 ? 242 GLN C CG 1 ATOM 8381 C CD . GLN C 2 210 ? 30.522 33.060 -2.312 1.00 85.98 ? 242 GLN C CD 1 ATOM 8382 O OE1 . GLN C 2 210 ? 30.350 33.027 -3.530 1.00 83.57 ? 242 GLN C OE1 1 ATOM 8383 N NE2 . GLN C 2 210 ? 30.834 34.176 -1.662 1.00 87.25 ? 242 GLN C NE2 1 ATOM 8384 N N . ASN C 2 211 ? 31.597 27.538 -3.233 1.00 77.28 ? 243 ASN C N 1 ATOM 8385 C CA . ASN C 2 211 ? 31.269 26.306 -3.954 1.00 75.63 ? 243 ASN C CA 1 ATOM 8386 C C . ASN C 2 211 ? 31.966 25.080 -3.359 1.00 79.46 ? 243 ASN C C 1 ATOM 8387 O O . ASN C 2 211 ? 32.268 24.131 -4.095 1.00 82.17 ? 243 ASN C O 1 ATOM 8388 C CB . ASN C 2 211 ? 31.644 26.430 -5.439 1.00 72.58 ? 243 ASN C CB 1 ATOM 8389 C CG . ASN C 2 211 ? 31.297 27.783 -6.024 1.00 67.49 ? 243 ASN C CG 1 ATOM 8390 O OD1 . ASN C 2 211 ? 30.842 28.681 -5.317 1.00 64.99 ? 243 ASN C OD1 1 ATOM 8391 N ND2 . ASN C 2 211 ? 31.522 27.940 -7.320 1.00 63.58 ? 243 ASN C ND2 1 ATOM 8392 N N . LYS C 2 212 ? 32.207 25.086 -2.042 1.00 80.72 ? 244 LYS C N 1 ATOM 8393 C CA . LYS C 2 212 ? 32.964 24.010 -1.381 1.00 83.02 ? 244 LYS C CA 1 ATOM 8394 C C . LYS C 2 212 ? 34.136 23.553 -2.271 1.00 79.00 ? 244 LYS C C 1 ATOM 8395 O O . LYS C 2 212 ? 34.204 22.383 -2.666 1.00 75.65 ? 244 LYS C O 1 ATOM 8396 C CB . LYS C 2 212 ? 32.073 22.787 -1.074 1.00 88.35 ? 244 LYS C CB 1 ATOM 8397 C CG . LYS C 2 212 ? 30.899 22.960 -0.108 1.00 92.21 ? 244 LYS C CG 1 ATOM 8398 C CD . LYS C 2 212 ? 30.543 21.598 0.518 1.00 96.59 ? 244 LYS C CD 1 ATOM 8399 C CE . LYS C 2 212 ? 29.104 21.465 1.031 1.00 95.10 ? 244 LYS C CE 1 ATOM 8400 N NZ . LYS C 2 212 ? 28.205 20.654 0.153 1.00 89.86 1 244 LYS C NZ 1 ATOM 8401 N N . GLU C 2 213 ? 35.032 24.476 -2.620 1.00 73.27 ? 245 GLU C N 1 ATOM 8402 C CA . GLU C 2 213 ? 36.188 24.135 -3.463 1.00 69.78 ? 245 GLU C CA 1 ATOM 8403 C C . GLU C 2 213 ? 37.518 24.378 -2.743 1.00 66.23 ? 245 GLU C C 1 ATOM 8404 O O . GLU C 2 213 ? 37.682 25.404 -2.074 1.00 63.60 ? 245 GLU C O 1 ATOM 8405 C CB . GLU C 2 213 ? 36.151 24.909 -4.787 1.00 69.80 ? 245 GLU C CB 1 ATOM 8406 C CG . GLU C 2 213 ? 35.436 24.163 -5.905 1.00 72.79 ? 245 GLU C CG 1 ATOM 8407 C CD . GLU C 2 213 ? 35.857 24.618 -7.291 1.00 73.86 ? 245 GLU C CD 1 ATOM 8408 O OE1 . GLU C 2 213 ? 36.043 25.838 -7.489 1.00 67.46 ? 245 GLU C OE1 1 ATOM 8409 O OE2 . GLU C 2 213 ? 35.999 23.747 -8.181 1.00 78.47 -1 245 GLU C OE2 1 ATOM 8410 N N . LYS C 2 214 ? 38.453 23.425 -2.878 1.00 60.56 ? 246 LYS C N 1 ATOM 8411 C CA . LYS C 2 214 ? 39.810 23.574 -2.338 1.00 57.11 ? 246 LYS C CA 1 ATOM 8412 C C . LYS C 2 214 ? 40.809 24.003 -3.411 1.00 50.94 ? 246 LYS C C 1 ATOM 8413 O O . LYS C 2 214 ? 40.885 23.439 -4.504 1.00 45.95 ? 246 LYS C O 1 ATOM 8414 C CB . LYS C 2 214 ? 40.288 22.297 -1.652 1.00 59.90 ? 246 LYS C CB 1 ATOM 8415 C CG . LYS C 2 214 ? 39.419 21.862 -0.474 1.00 63.27 ? 246 LYS C CG 1 ATOM 8416 C CD . LYS C 2 214 ? 39.475 22.787 0.738 1.00 62.81 ? 246 LYS C CD 1 ATOM 8417 C CE . LYS C 2 214 ? 40.810 22.697 1.442 1.00 66.01 ? 246 LYS C CE 1 ATOM 8418 N NZ . LYS C 2 214 ? 40.797 23.224 2.833 1.00 69.85 1 246 LYS C NZ 1 ATOM 8419 N N . VAL C 2 215 ? 41.571 25.028 -3.059 1.00 47.19 ? 247 VAL C N 1 ATOM 8420 C CA . VAL C 2 215 ? 42.467 25.692 -3.969 1.00 45.08 ? 247 VAL C CA 1 ATOM 8421 C C . VAL C 2 215 ? 43.905 25.309 -3.599 1.00 45.47 ? 247 VAL C C 1 ATOM 8422 O O . VAL C 2 215 ? 44.259 25.248 -2.399 1.00 45.42 ? 247 VAL C O 1 ATOM 8423 C CB . VAL C 2 215 ? 42.230 27.225 -3.918 1.00 42.96 ? 247 VAL C CB 1 ATOM 8424 C CG1 . VAL C 2 215 ? 43.454 28.029 -4.368 1.00 42.67 ? 247 VAL C CG1 1 ATOM 8425 C CG2 . VAL C 2 215 ? 41.020 27.568 -4.761 1.00 42.22 ? 247 VAL C CG2 1 ATOM 8426 N N . TYR C 2 216 ? 44.701 25.006 -4.638 1.00 41.67 ? 248 TYR C N 1 ATOM 8427 C CA . TYR C 2 216 ? 46.180 24.975 -4.567 1.00 37.81 ? 248 TYR C CA 1 ATOM 8428 C C . TYR C 2 216 ? 46.817 26.102 -5.412 1.00 36.49 ? 248 TYR C C 1 ATOM 8429 O O . TYR C 2 216 ? 46.685 26.122 -6.627 1.00 36.60 ? 248 TYR C O 1 ATOM 8430 C CB . TYR C 2 216 ? 46.745 23.646 -5.082 1.00 34.93 ? 248 TYR C CB 1 ATOM 8431 C CG . TYR C 2 216 ? 46.540 22.414 -4.223 1.00 32.65 ? 248 TYR C CG 1 ATOM 8432 C CD1 . TYR C 2 216 ? 46.073 22.491 -2.902 1.00 31.27 ? 248 TYR C CD1 1 ATOM 8433 C CD2 . TYR C 2 216 ? 46.876 21.163 -4.732 1.00 31.34 ? 248 TYR C CD2 1 ATOM 8434 C CE1 . TYR C 2 216 ? 45.904 21.340 -2.151 1.00 30.91 ? 248 TYR C CE1 1 ATOM 8435 C CE2 . TYR C 2 216 ? 46.719 20.019 -3.986 1.00 30.88 ? 248 TYR C CE2 1 ATOM 8436 C CZ . TYR C 2 216 ? 46.227 20.110 -2.711 1.00 31.46 ? 248 TYR C CZ 1 ATOM 8437 O OH . TYR C 2 216 ? 46.083 18.954 -1.990 1.00 34.22 ? 248 TYR C OH 1 ATOM 8438 N N . ILE C 2 217 ? 47.541 27.011 -4.768 1.00 36.61 ? 249 ILE C N 1 ATOM 8439 C CA . ILE C 2 217 ? 48.293 28.048 -5.474 1.00 35.17 ? 249 ILE C CA 1 ATOM 8440 C C . ILE C 2 217 ? 49.578 27.459 -6.112 1.00 35.20 ? 249 ILE C C 1 ATOM 8441 O O . ILE C 2 217 ? 50.401 26.833 -5.434 1.00 33.23 ? 249 ILE C O 1 ATOM 8442 C CB . ILE C 2 217 ? 48.673 29.224 -4.538 1.00 34.07 ? 249 ILE C CB 1 ATOM 8443 C CG1 . ILE C 2 217 ? 47.472 29.768 -3.761 1.00 32.60 ? 249 ILE C CG1 1 ATOM 8444 C CG2 . ILE C 2 217 ? 49.281 30.344 -5.342 1.00 36.09 ? 249 ILE C CG2 1 ATOM 8445 C CD1 . ILE C 2 217 ? 46.260 30.090 -4.602 1.00 32.43 ? 249 ILE C CD1 1 ATOM 8446 N N . ILE C 2 218 ? 49.709 27.651 -7.427 1.00 35.70 ? 250 ILE C N 1 ATOM 8447 C CA . ILE C 2 218 ? 50.922 27.342 -8.218 1.00 38.24 ? 250 ILE C CA 1 ATOM 8448 C C . ILE C 2 218 ? 51.452 28.683 -8.744 1.00 39.51 ? 250 ILE C C 1 ATOM 8449 O O . ILE C 2 218 ? 50.690 29.463 -9.282 1.00 45.79 ? 250 ILE C O 1 ATOM 8450 C CB . ILE C 2 218 ? 50.583 26.337 -9.373 1.00 39.23 ? 250 ILE C CB 1 ATOM 8451 C CG1 . ILE C 2 218 ? 50.876 24.922 -8.911 1.00 42.34 ? 250 ILE C CG1 1 ATOM 8452 C CG2 . ILE C 2 218 ? 51.355 26.563 -10.676 1.00 36.58 ? 250 ILE C CG2 1 ATOM 8453 C CD1 . ILE C 2 218 ? 50.127 24.503 -7.671 1.00 43.65 ? 250 ILE C CD1 1 ATOM 8454 N N . ALA C 2 219 ? 52.730 28.993 -8.547 1.00 38.43 ? 251 ALA C N 1 ATOM 8455 C CA . ALA C 2 219 ? 53.316 30.230 -9.094 1.00 35.13 ? 251 ALA C CA 1 ATOM 8456 C C . ALA C 2 219 ? 54.798 30.056 -9.051 1.00 33.55 ? 251 ALA C C 1 ATOM 8457 O O . ALA C 2 219 ? 55.304 29.211 -8.308 1.00 31.74 ? 251 ALA C O 1 ATOM 8458 C CB . ALA C 2 219 ? 52.910 31.457 -8.285 1.00 35.19 ? 251 ALA C CB 1 ATOM 8459 N N . HIS C 2 220 ? 55.545 30.814 -9.851 1.00 33.17 ? 252 HIS C N 1 ATOM 8460 C CA . HIS C 2 220 ? 57.022 30.713 -9.888 1.00 34.19 ? 252 HIS C CA 1 ATOM 8461 C C . HIS C 2 220 ? 57.758 31.544 -8.842 1.00 35.32 ? 252 HIS C C 1 ATOM 8462 O O . HIS C 2 220 ? 58.417 30.987 -7.997 1.00 34.01 ? 252 HIS C O 1 ATOM 8463 C CB . HIS C 2 220 ? 57.583 30.952 -11.312 1.00 33.49 ? 252 HIS C CB 1 ATOM 8464 C CG . HIS C 2 220 ? 59.078 31.104 -11.407 1.00 32.21 ? 252 HIS C CG 1 ATOM 8465 N ND1 . HIS C 2 220 ? 59.939 30.043 -11.457 1.00 31.27 ? 252 HIS C ND1 1 ATOM 8466 C CD2 . HIS C 2 220 ? 59.849 32.203 -11.560 1.00 31.78 ? 252 HIS C CD2 1 ATOM 8467 C CE1 . HIS C 2 220 ? 61.177 30.483 -11.584 1.00 31.04 ? 252 HIS C CE1 1 ATOM 8468 N NE2 . HIS C 2 220 ? 61.155 31.795 -11.636 1.00 31.50 ? 252 HIS C NE2 1 ATOM 8469 N N . VAL C 2 221 ? 57.658 32.865 -8.886 1.00 33.92 ? 253 VAL C N 1 ATOM 8470 C CA . VAL C 2 221 ? 58.344 33.676 -7.900 1.00 34.02 ? 253 VAL C CA 1 ATOM 8471 C C . VAL C 2 221 ? 57.524 33.473 -6.684 1.00 33.79 ? 253 VAL C C 1 ATOM 8472 O O . VAL C 2 221 ? 56.329 33.479 -6.789 1.00 35.22 ? 253 VAL C O 1 ATOM 8473 C CB . VAL C 2 221 ? 58.346 35.175 -8.241 1.00 33.95 ? 253 VAL C CB 1 ATOM 8474 C CG1 . VAL C 2 221 ? 58.860 35.989 -7.096 1.00 33.04 ? 253 VAL C CG1 1 ATOM 8475 C CG2 . VAL C 2 221 ? 59.224 35.468 -9.416 1.00 34.99 ? 253 VAL C CG2 1 ATOM 8476 N N . PRO C 2 222 ? 58.205 33.274 -5.494 1.00 32.08 ? 254 PRO C N 1 ATOM 8477 C CA . PRO C 2 222 ? 57.349 33.130 -4.339 1.00 31.17 ? 254 PRO C CA 1 ATOM 8478 C C . PRO C 2 222 ? 57.096 34.417 -3.635 1.00 31.49 ? 254 PRO C C 1 ATOM 8479 O O . PRO C 2 222 ? 57.661 35.420 -3.928 1.00 26.99 ? 254 PRO C O 1 ATOM 8480 C CB . PRO C 2 222 ? 58.195 32.294 -3.389 1.00 31.54 ? 254 PRO C CB 1 ATOM 8481 C CG . PRO C 2 222 ? 59.399 31.871 -4.093 1.00 32.19 ? 254 PRO C CG 1 ATOM 8482 C CD . PRO C 2 222 ? 59.619 32.967 -5.020 1.00 31.86 ? 254 PRO C CD 1 ATOM 8483 N N . VAL C 2 223 ? 56.196 34.347 -2.680 1.00 33.26 ? 255 VAL C N 1 ATOM 8484 C CA . VAL C 2 223 ? 55.967 35.364 -1.676 1.00 32.96 ? 255 VAL C CA 1 ATOM 8485 C C . VAL C 2 223 ? 56.977 35.105 -0.538 1.00 37.02 ? 255 VAL C C 1 ATOM 8486 O O . VAL C 2 223 ? 57.687 34.066 -0.486 1.00 35.04 ? 255 VAL C O 1 ATOM 8487 C CB . VAL C 2 223 ? 54.516 35.336 -1.141 1.00 31.24 ? 255 VAL C CB 1 ATOM 8488 C CG1 . VAL C 2 223 ? 53.533 35.362 -2.297 1.00 31.65 ? 255 VAL C CG1 1 ATOM 8489 C CG2 . VAL C 2 223 ? 54.255 34.120 -0.269 1.00 29.84 ? 255 VAL C CG2 1 ATOM 8490 N N . GLY C 2 224 ? 57.065 36.075 0.363 1.00 41.73 ? 256 GLY C N 1 ATOM 8491 C CA . GLY C 2 224 ? 57.963 35.977 1.510 1.00 43.11 ? 256 GLY C CA 1 ATOM 8492 C C . GLY C 2 224 ? 59.389 36.389 1.209 1.00 43.93 ? 256 GLY C C 1 ATOM 8493 O O . GLY C 2 224 ? 59.735 36.748 0.076 1.00 48.64 ? 256 GLY C O 1 ATOM 8494 N N . TYR C 2 225 ? 60.213 36.325 2.250 1.00 41.20 ? 257 TYR C N 1 ATOM 8495 C CA . TYR C 2 225 ? 61.588 36.814 2.214 1.00 38.42 ? 257 TYR C CA 1 ATOM 8496 C C . TYR C 2 225 ? 62.553 35.708 1.709 1.00 39.06 ? 257 TYR C C 1 ATOM 8497 O O . TYR C 2 225 ? 62.333 34.524 1.976 1.00 41.16 ? 257 TYR C O 1 ATOM 8498 C CB . TYR C 2 225 ? 61.949 37.408 3.603 1.00 36.16 ? 257 TYR C CB 1 ATOM 8499 C CG . TYR C 2 225 ? 61.218 38.713 3.816 1.00 33.69 ? 257 TYR C CG 1 ATOM 8500 C CD1 . TYR C 2 225 ? 59.877 38.737 4.189 1.00 32.80 ? 257 TYR C CD1 1 ATOM 8501 C CD2 . TYR C 2 225 ? 61.848 39.923 3.545 1.00 34.44 ? 257 TYR C CD2 1 ATOM 8502 C CE1 . TYR C 2 225 ? 59.189 39.928 4.319 1.00 32.90 ? 257 TYR C CE1 1 ATOM 8503 C CE2 . TYR C 2 225 ? 61.176 41.126 3.675 1.00 34.91 ? 257 TYR C CE2 1 ATOM 8504 C CZ . TYR C 2 225 ? 59.845 41.121 4.057 1.00 35.22 ? 257 TYR C CZ 1 ATOM 8505 O OH . TYR C 2 225 ? 59.181 42.319 4.168 1.00 38.39 ? 257 TYR C OH 1 ATOM 8506 N N . LEU C 2 226 ? 63.575 36.085 0.930 1.00 37.70 ? 258 LEU C N 1 ATOM 8507 C CA . LEU C 2 226 ? 64.554 35.119 0.435 1.00 35.45 ? 258 LEU C CA 1 ATOM 8508 C C . LEU C 2 226 ? 65.391 34.721 1.610 1.00 36.73 ? 258 LEU C C 1 ATOM 8509 O O . LEU C 2 226 ? 65.872 35.591 2.351 1.00 36.53 ? 258 LEU C O 1 ATOM 8510 C CB . LEU C 2 226 ? 65.431 35.701 -0.655 1.00 34.43 ? 258 LEU C CB 1 ATOM 8511 C CG . LEU C 2 226 ? 64.648 35.977 -1.935 1.00 33.89 ? 258 LEU C CG 1 ATOM 8512 C CD1 . LEU C 2 226 ? 65.372 37.046 -2.739 1.00 33.37 ? 258 LEU C CD1 1 ATOM 8513 C CD2 . LEU C 2 226 ? 64.388 34.687 -2.732 1.00 33.63 ? 258 LEU C CD2 1 ATOM 8514 N N . PRO C 2 227 ? 65.541 33.407 1.814 1.00 39.75 ? 259 PRO C N 1 ATOM 8515 C CA . PRO C 2 227 ? 66.048 32.972 3.108 1.00 41.52 ? 259 PRO C CA 1 ATOM 8516 C C . PRO C 2 227 ? 67.560 33.199 3.301 1.00 41.84 ? 259 PRO C C 1 ATOM 8517 O O . PRO C 2 227 ? 68.022 33.352 4.443 1.00 41.18 ? 259 PRO C O 1 ATOM 8518 C CB . PRO C 2 227 ? 65.687 31.455 3.145 1.00 41.38 ? 259 PRO C CB 1 ATOM 8519 C CG . PRO C 2 227 ? 64.927 31.158 1.890 1.00 40.60 ? 259 PRO C CG 1 ATOM 8520 C CD . PRO C 2 227 ? 65.301 32.255 0.925 1.00 41.33 ? 259 PRO C CD 1 ATOM 8521 N N A SER C 2 228 ? 68.336 33.189 2.214 0.50 41.10 ? 260 SER C N 1 ATOM 8522 N N B SER C 2 228 ? 68.287 33.258 2.189 0.50 41.42 ? 260 SER C N 1 ATOM 8523 C CA A SER C 2 228 ? 69.785 33.361 2.334 0.50 39.69 ? 260 SER C CA 1 ATOM 8524 C CA B SER C 2 228 ? 69.731 33.364 2.195 0.50 40.25 ? 260 SER C CA 1 ATOM 8525 C C A SER C 2 228 ? 70.218 34.828 2.222 0.50 40.81 ? 260 SER C C 1 ATOM 8526 C C B SER C 2 228 ? 70.210 34.824 2.214 0.50 41.15 ? 260 SER C C 1 ATOM 8527 O O A SER C 2 228 ? 71.359 35.116 1.874 0.50 41.27 ? 260 SER C O 1 ATOM 8528 O O B SER C 2 228 ? 71.378 35.100 1.955 0.50 41.57 ? 260 SER C O 1 ATOM 8529 C CB A SER C 2 228 ? 70.533 32.471 1.340 0.50 37.64 ? 260 SER C CB 1 ATOM 8530 C CB B SER C 2 228 ? 70.241 32.623 0.972 0.50 38.69 ? 260 SER C CB 1 ATOM 8531 O OG A SER C 2 228 ? 71.024 31.305 1.991 0.50 35.86 ? 260 SER C OG 1 ATOM 8532 O OG B SER C 2 228 ? 69.133 32.299 0.142 0.50 37.75 ? 260 SER C OG 1 ATOM 8533 N N . SER C 2 229 ? 69.319 35.755 2.544 1.00 41.25 ? 261 SER C N 1 ATOM 8534 C CA . SER C 2 229 ? 69.681 37.163 2.611 1.00 42.88 ? 261 SER C CA 1 ATOM 8535 C C . SER C 2 229 ? 68.626 37.983 3.363 1.00 44.72 ? 261 SER C C 1 ATOM 8536 O O . SER C 2 229 ? 67.474 37.536 3.565 1.00 44.72 ? 261 SER C O 1 ATOM 8537 C CB . SER C 2 229 ? 70.006 37.760 1.210 1.00 42.50 ? 261 SER C CB 1 ATOM 8538 O OG . SER C 2 229 ? 68.993 37.552 0.244 1.00 40.32 ? 261 SER C OG 1 ATOM 8539 N N . GLN C 2 230 ? 69.047 39.190 3.754 1.00 44.03 ? 262 GLN C N 1 ATOM 8540 C CA . GLN C 2 230 ? 68.380 39.943 4.792 1.00 45.62 ? 262 GLN C CA 1 ATOM 8541 C C . GLN C 2 230 ? 67.468 41.052 4.248 1.00 44.00 ? 262 GLN C C 1 ATOM 8542 O O . GLN C 2 230 ? 67.880 41.877 3.450 1.00 43.37 ? 262 GLN C O 1 ATOM 8543 C CB . GLN C 2 230 ? 69.417 40.448 5.826 1.00 50.06 ? 262 GLN C CB 1 ATOM 8544 C CG . GLN C 2 230 ? 69.682 41.958 5.908 1.00 55.80 ? 262 GLN C CG 1 ATOM 8545 C CD . GLN C 2 230 ? 70.365 42.394 7.215 1.00 55.29 ? 262 GLN C CD 1 ATOM 8546 O OE1 . GLN C 2 230 ? 69.936 43.362 7.854 1.00 56.47 ? 262 GLN C OE1 1 ATOM 8547 N NE2 . GLN C 2 230 ? 71.427 41.691 7.607 1.00 50.86 ? 262 GLN C NE2 1 ATOM 8548 N N . ASN C 2 231 ? 66.216 41.024 4.703 1.00 44.86 ? 263 ASN C N 1 ATOM 8549 C CA . ASN C 2 231 ? 65.179 41.995 4.357 1.00 45.69 ? 263 ASN C CA 1 ATOM 8550 C C . ASN C 2 231 ? 64.950 42.087 2.840 1.00 46.14 ? 263 ASN C C 1 ATOM 8551 O O . ASN C 2 231 ? 64.698 43.176 2.318 1.00 46.52 ? 263 ASN C O 1 ATOM 8552 C CB . ASN C 2 231 ? 65.491 43.381 4.976 1.00 45.14 ? 263 ASN C CB 1 ATOM 8553 C CG . ASN C 2 231 ? 64.241 44.262 5.152 1.00 46.00 ? 263 ASN C CG 1 ATOM 8554 O OD1 . ASN C 2 231 ? 63.147 43.772 5.450 1.00 43.87 ? 263 ASN C OD1 1 ATOM 8555 N ND2 . ASN C 2 231 ? 64.411 45.580 4.965 1.00 49.42 ? 263 ASN C ND2 1 ATOM 8556 N N . ILE C 2 232 ? 65.039 40.955 2.132 1.00 44.56 ? 264 ILE C N 1 ATOM 8557 C CA . ILE C 2 232 ? 64.784 40.954 0.675 1.00 42.30 ? 264 ILE C CA 1 ATOM 8558 C C . ILE C 2 232 ? 63.661 40.007 0.268 1.00 37.54 ? 264 ILE C C 1 ATOM 8559 O O . ILE C 2 232 ? 63.889 38.827 0.040 1.00 34.90 ? 264 ILE C O 1 ATOM 8560 C CB . ILE C 2 232 ? 66.034 40.613 -0.175 1.00 43.93 ? 264 ILE C CB 1 ATOM 8561 C CG1 . ILE C 2 232 ? 67.186 41.585 0.115 1.00 44.53 ? 264 ILE C CG1 1 ATOM 8562 C CG2 . ILE C 2 232 ? 65.697 40.645 -1.670 1.00 42.65 ? 264 ILE C CG2 1 ATOM 8563 C CD1 . ILE C 2 232 ? 68.549 40.932 -0.054 1.00 45.14 ? 264 ILE C CD1 1 ATOM 8564 N N . THR C 2 233 ? 62.459 40.570 0.175 1.00 35.13 ? 265 THR C N 1 ATOM 8565 C CA . THR C 2 233 ? 61.324 39.984 -0.514 1.00 33.13 ? 265 THR C CA 1 ATOM 8566 C C . THR C 2 233 ? 61.764 39.547 -1.874 1.00 33.69 ? 265 THR C C 1 ATOM 8567 O O . THR C 2 233 ? 62.557 40.244 -2.508 1.00 34.34 ? 265 THR C O 1 ATOM 8568 C CB . THR C 2 233 ? 60.279 41.060 -0.764 1.00 32.96 ? 265 THR C CB 1 ATOM 8569 O OG1 . THR C 2 233 ? 60.950 42.257 -1.235 1.00 29.34 ? 265 THR C OG1 1 ATOM 8570 C CG2 . THR C 2 233 ? 59.510 41.339 0.527 1.00 33.99 ? 265 THR C CG2 1 ATOM 8571 N N . ALA C 2 234 ? 61.240 38.413 -2.329 1.00 33.31 ? 266 ALA C N 1 ATOM 8572 C CA . ALA C 2 234 ? 61.602 37.864 -3.632 1.00 35.40 ? 266 ALA C CA 1 ATOM 8573 C C . ALA C 2 234 ? 60.893 38.627 -4.755 1.00 37.91 ? 266 ALA C C 1 ATOM 8574 O O . ALA C 2 234 ? 61.443 38.829 -5.862 1.00 36.26 ? 266 ALA C O 1 ATOM 8575 C CB . ALA C 2 234 ? 61.251 36.386 -3.685 1.00 35.87 ? 266 ALA C CB 1 ATOM 8576 N N . MET C 2 235 ? 59.646 39.005 -4.449 1.00 43.04 ? 267 MET C N 1 ATOM 8577 C CA . MET C 2 235 ? 58.855 39.998 -5.211 1.00 45.33 ? 267 MET C CA 1 ATOM 8578 C C . MET C 2 235 ? 59.219 41.443 -4.787 1.00 46.60 ? 267 MET C C 1 ATOM 8579 O O . MET C 2 235 ? 59.980 41.669 -3.824 1.00 48.23 ? 267 MET C O 1 ATOM 8580 C CB . MET C 2 235 ? 57.343 39.790 -4.961 1.00 42.34 ? 267 MET C CB 1 ATOM 8581 C CG . MET C 2 235 ? 56.768 38.485 -5.490 1.00 41.17 ? 267 MET C CG 1 ATOM 8582 S SD . MET C 2 235 ? 55.243 37.987 -4.673 1.00 39.22 ? 267 MET C SD 1 ATOM 8583 C CE . MET C 2 235 ? 54.393 39.549 -4.588 1.00 38.75 ? 267 MET C CE 1 ATOM 8584 N N . ARG C 2 236 ? 58.673 42.420 -5.506 1.00 44.75 ? 268 ARG C N 1 ATOM 8585 C CA . ARG C 2 236 ? 58.654 43.770 -4.987 1.00 45.50 ? 268 ARG C CA 1 ATOM 8586 C C . ARG C 2 236 ? 57.866 43.657 -3.652 1.00 50.96 ? 268 ARG C C 1 ATOM 8587 O O . ARG C 2 236 ? 56.777 43.054 -3.595 1.00 49.85 ? 268 ARG C O 1 ATOM 8588 C CB . ARG C 2 236 ? 58.110 44.753 -6.023 1.00 42.62 ? 268 ARG C CB 1 ATOM 8589 C CG . ARG C 2 236 ? 59.164 45.391 -6.896 1.00 39.66 ? 268 ARG C CG 1 ATOM 8590 C CD . ARG C 2 236 ? 58.558 46.411 -7.854 1.00 37.30 ? 268 ARG C CD 1 ATOM 8591 N NE . ARG C 2 236 ? 59.073 46.132 -9.197 1.00 37.43 ? 268 ARG C NE 1 ATOM 8592 C CZ . ARG C 2 236 ? 58.359 46.021 -10.324 1.00 35.88 ? 268 ARG C CZ 1 ATOM 8593 N NH1 . ARG C 2 236 ? 57.042 46.223 -10.352 1.00 36.15 1 268 ARG C NH1 1 ATOM 8594 N NH2 . ARG C 2 236 ? 58.987 45.732 -11.456 1.00 33.69 ? 268 ARG C NH2 1 ATOM 8595 N N . GLU C 2 237 ? 58.467 44.208 -2.593 1.00 54.39 ? 269 GLU C N 1 ATOM 8596 C CA . GLU C 2 237 ? 57.860 44.470 -1.287 1.00 57.50 ? 269 GLU C CA 1 ATOM 8597 C C . GLU C 2 237 ? 56.398 44.860 -1.358 1.00 62.07 ? 269 GLU C C 1 ATOM 8598 O O . GLU C 2 237 ? 55.545 44.301 -0.652 1.00 63.07 ? 269 GLU C O 1 ATOM 8599 C CB . GLU C 2 237 ? 58.631 45.618 -0.631 1.00 59.54 ? 269 GLU C CB 1 ATOM 8600 C CG . GLU C 2 237 ? 57.933 46.327 0.523 1.00 60.46 ? 269 GLU C CG 1 ATOM 8601 C CD . GLU C 2 237 ? 58.152 45.641 1.850 1.00 64.26 ? 269 GLU C CD 1 ATOM 8602 O OE1 . GLU C 2 237 ? 59.139 44.877 2.010 1.00 64.62 ? 269 GLU C OE1 1 ATOM 8603 O OE2 . GLU C 2 237 ? 57.320 45.883 2.740 1.00 69.58 -1 269 GLU C OE2 1 ATOM 8604 N N . TYR C 2 238 ? 56.127 45.864 -2.188 1.00 68.49 ? 270 TYR C N 1 ATOM 8605 C CA . TYR C 2 238 ? 54.778 46.398 -2.327 1.00 66.60 ? 270 TYR C CA 1 ATOM 8606 C C . TYR C 2 238 ? 53.799 45.260 -2.681 1.00 58.36 ? 270 TYR C C 1 ATOM 8607 O O . TYR C 2 238 ? 52.809 45.055 -1.987 1.00 53.50 ? 270 TYR C O 1 ATOM 8608 C CB . TYR C 2 238 ? 54.740 47.568 -3.335 1.00 64.74 ? 270 TYR C CB 1 ATOM 8609 C CG . TYR C 2 238 ? 53.337 47.926 -3.687 1.00 65.38 ? 270 TYR C CG 1 ATOM 8610 C CD1 . TYR C 2 238 ? 52.548 48.704 -2.831 1.00 65.59 ? 270 TYR C CD1 1 ATOM 8611 C CD2 . TYR C 2 238 ? 52.767 47.425 -4.848 1.00 67.83 ? 270 TYR C CD2 1 ATOM 8612 C CE1 . TYR C 2 238 ? 51.225 48.991 -3.154 1.00 70.71 ? 270 TYR C CE1 1 ATOM 8613 C CE2 . TYR C 2 238 ? 51.457 47.704 -5.187 1.00 71.66 ? 270 TYR C CE2 1 ATOM 8614 C CZ . TYR C 2 238 ? 50.682 48.480 -4.350 1.00 73.35 ? 270 TYR C CZ 1 ATOM 8615 O OH . TYR C 2 238 ? 49.376 48.707 -4.752 1.00 73.35 ? 270 TYR C OH 1 ATOM 8616 N N . TYR C 2 239 ? 54.117 44.492 -3.715 1.00 54.94 ? 271 TYR C N 1 ATOM 8617 C CA . TYR C 2 239 ? 53.258 43.384 -4.133 1.00 54.91 ? 271 TYR C CA 1 ATOM 8618 C C . TYR C 2 239 ? 53.164 42.259 -3.110 1.00 52.73 ? 271 TYR C C 1 ATOM 8619 O O . TYR C 2 239 ? 52.098 41.665 -2.924 1.00 52.16 ? 271 TYR C O 1 ATOM 8620 C CB . TYR C 2 239 ? 53.752 42.791 -5.446 1.00 55.35 ? 271 TYR C CB 1 ATOM 8621 C CG . TYR C 2 239 ? 53.709 43.756 -6.596 1.00 59.65 ? 271 TYR C CG 1 ATOM 8622 C CD1 . TYR C 2 239 ? 52.549 44.461 -6.906 1.00 61.60 ? 271 TYR C CD1 1 ATOM 8623 C CD2 . TYR C 2 239 ? 54.830 43.961 -7.393 1.00 63.89 ? 271 TYR C CD2 1 ATOM 8624 C CE1 . TYR C 2 239 ? 52.512 45.351 -7.973 1.00 62.21 ? 271 TYR C CE1 1 ATOM 8625 C CE2 . TYR C 2 239 ? 54.799 44.842 -8.462 1.00 63.30 ? 271 TYR C CE2 1 ATOM 8626 C CZ . TYR C 2 239 ? 53.640 45.533 -8.750 1.00 61.22 ? 271 TYR C CZ 1 ATOM 8627 O OH . TYR C 2 239 ? 53.601 46.401 -9.808 1.00 58.59 ? 271 TYR C OH 1 ATOM 8628 N N . ASN C 2 240 ? 54.283 41.938 -2.476 1.00 48.52 ? 272 ASN C N 1 ATOM 8629 C CA . ASN C 2 240 ? 54.292 40.872 -1.503 1.00 43.49 ? 272 ASN C CA 1 ATOM 8630 C C . ASN C 2 240 ? 53.318 41.137 -0.349 1.00 44.02 ? 272 ASN C C 1 ATOM 8631 O O . ASN C 2 240 ? 52.575 40.253 0.029 1.00 45.74 ? 272 ASN C O 1 ATOM 8632 C CB . ASN C 2 240 ? 55.694 40.622 -0.988 1.00 40.29 ? 272 ASN C CB 1 ATOM 8633 C CG . ASN C 2 240 ? 55.681 39.715 0.186 1.00 38.26 ? 272 ASN C CG 1 ATOM 8634 O OD1 . ASN C 2 240 ? 55.250 38.567 0.089 1.00 34.37 ? 272 ASN C OD1 1 ATOM 8635 N ND2 . ASN C 2 240 ? 56.070 40.244 1.327 1.00 40.07 ? 272 ASN C ND2 1 ATOM 8636 N N . GLU C 2 241 ? 53.284 42.354 0.183 1.00 46.07 ? 273 GLU C N 1 ATOM 8637 C CA . GLU C 2 241 ? 52.323 42.685 1.254 1.00 48.91 ? 273 GLU C CA 1 ATOM 8638 C C . GLU C 2 241 ? 50.862 42.509 0.803 1.00 51.99 ? 273 GLU C C 1 ATOM 8639 O O . GLU C 2 241 ? 50.033 41.975 1.541 1.00 53.84 ? 273 GLU C O 1 ATOM 8640 C CB . GLU C 2 241 ? 52.524 44.118 1.737 1.00 47.31 ? 273 GLU C CB 1 ATOM 8641 C CG . GLU C 2 241 ? 53.850 44.368 2.419 1.00 48.99 ? 273 GLU C CG 1 ATOM 8642 C CD . GLU C 2 241 ? 54.026 43.608 3.730 1.00 52.18 ? 273 GLU C CD 1 ATOM 8643 O OE1 . GLU C 2 241 ? 53.062 43.481 4.532 1.00 49.64 ? 273 GLU C OE1 1 ATOM 8644 O OE2 . GLU C 2 241 ? 55.172 43.149 3.964 1.00 55.59 -1 273 GLU C OE2 1 ATOM 8645 N N . LYS C 2 242 ? 50.579 42.994 -0.408 1.00 53.26 ? 274 LYS C N 1 ATOM 8646 C CA . LYS C 2 242 ? 49.290 42.859 -1.097 1.00 51.26 ? 274 LYS C CA 1 ATOM 8647 C C . LYS C 2 242 ? 48.881 41.364 -1.214 1.00 49.52 ? 274 LYS C C 1 ATOM 8648 O O . LYS C 2 242 ? 47.743 40.981 -0.900 1.00 47.34 ? 274 LYS C O 1 ATOM 8649 C CB . LYS C 2 242 ? 49.434 43.492 -2.500 1.00 51.56 ? 274 LYS C CB 1 ATOM 8650 C CG . LYS C 2 242 ? 48.177 44.040 -3.142 1.00 54.58 ? 274 LYS C CG 1 ATOM 8651 C CD . LYS C 2 242 ? 48.232 45.558 -3.261 1.00 59.47 ? 274 LYS C CD 1 ATOM 8652 C CE . LYS C 2 242 ? 47.348 46.068 -4.399 1.00 61.76 ? 274 LYS C CE 1 ATOM 8653 N NZ . LYS C 2 242 ? 45.947 45.544 -4.324 1.00 63.19 1 274 LYS C NZ 1 ATOM 8654 N N . LEU C 2 243 ? 49.827 40.529 -1.656 1.00 48.68 ? 275 LEU C N 1 ATOM 8655 C CA . LEU C 2 243 ? 49.583 39.089 -1.895 1.00 46.80 ? 275 LEU C CA 1 ATOM 8656 C C . LEU C 2 243 ? 49.346 38.317 -0.633 1.00 44.57 ? 275 LEU C C 1 ATOM 8657 O O . LEU C 2 243 ? 48.576 37.355 -0.652 1.00 42.56 ? 275 LEU C O 1 ATOM 8658 C CB . LEU C 2 243 ? 50.766 38.404 -2.606 1.00 46.07 ? 275 LEU C CB 1 ATOM 8659 C CG . LEU C 2 243 ? 50.700 38.062 -4.092 1.00 44.60 ? 275 LEU C CG 1 ATOM 8660 C CD1 . LEU C 2 243 ? 51.790 37.054 -4.472 1.00 44.02 ? 275 LEU C CD1 1 ATOM 8661 C CD2 . LEU C 2 243 ? 49.337 37.489 -4.409 1.00 44.82 ? 275 LEU C CD2 1 ATOM 8662 N N . ILE C 2 244 ? 50.062 38.706 0.427 1.00 44.19 ? 276 ILE C N 1 ATOM 8663 C CA . ILE C 2 244 ? 49.917 38.099 1.751 1.00 45.84 ? 276 ILE C CA 1 ATOM 8664 C C . ILE C 2 244 ? 48.552 38.500 2.339 1.00 46.19 ? 276 ILE C C 1 ATOM 8665 O O . ILE C 2 244 ? 47.866 37.655 2.912 1.00 45.71 ? 276 ILE C O 1 ATOM 8666 C CB . ILE C 2 244 ? 51.082 38.489 2.724 1.00 47.92 ? 276 ILE C CB 1 ATOM 8667 C CG1 . ILE C 2 244 ? 52.472 38.056 2.191 1.00 49.36 ? 276 ILE C CG1 1 ATOM 8668 C CG2 . ILE C 2 244 ? 50.865 37.908 4.128 1.00 47.27 ? 276 ILE C CG2 1 ATOM 8669 C CD1 . ILE C 2 244 ? 52.575 36.624 1.695 1.00 49.21 ? 276 ILE C CD1 1 ATOM 8670 N N . ASP C 2 245 ? 48.154 39.768 2.183 1.00 46.63 ? 277 ASP C N 1 ATOM 8671 C CA . ASP C 2 245 ? 46.840 40.232 2.659 1.00 48.40 ? 277 ASP C CA 1 ATOM 8672 C C . ASP C 2 245 ? 45.697 39.475 2.006 1.00 49.02 ? 277 ASP C C 1 ATOM 8673 O O . ASP C 2 245 ? 44.767 39.046 2.691 1.00 49.12 ? 277 ASP C O 1 ATOM 8674 C CB . ASP C 2 245 ? 46.660 41.739 2.452 1.00 52.95 ? 277 ASP C CB 1 ATOM 8675 C CG . ASP C 2 245 ? 47.014 42.556 3.707 1.00 61.01 ? 277 ASP C CG 1 ATOM 8676 O OD1 . ASP C 2 245 ? 47.524 41.990 4.703 1.00 69.51 ? 277 ASP C OD1 1 ATOM 8677 O OD2 . ASP C 2 245 ? 46.773 43.782 3.717 1.00 66.65 -1 277 ASP C OD2 1 ATOM 8678 N N . ILE C 2 246 ? 45.779 39.284 0.692 1.00 47.76 ? 278 ILE C N 1 ATOM 8679 C CA . ILE C 2 246 ? 44.845 38.386 0.000 1.00 46.28 ? 278 ILE C CA 1 ATOM 8680 C C . ILE C 2 246 ? 44.836 36.934 0.580 1.00 44.16 ? 278 ILE C C 1 ATOM 8681 O O . ILE C 2 246 ? 43.775 36.446 0.958 1.00 40.69 ? 278 ILE C O 1 ATOM 8682 C CB . ILE C 2 246 ? 45.083 38.377 -1.531 1.00 44.58 ? 278 ILE C CB 1 ATOM 8683 C CG1 . ILE C 2 246 ? 44.861 39.778 -2.124 1.00 42.17 ? 278 ILE C CG1 1 ATOM 8684 C CG2 . ILE C 2 246 ? 44.142 37.377 -2.196 1.00 44.82 ? 278 ILE C CG2 1 ATOM 8685 C CD1 . ILE C 2 246 ? 45.436 39.974 -3.514 1.00 39.77 ? 278 ILE C CD1 1 ATOM 8686 N N . PHE C 2 247 ? 45.998 36.263 0.649 1.00 46.69 ? 279 PHE C N 1 ATOM 8687 C CA . PHE C 2 247 ? 46.104 34.868 1.204 1.00 46.89 ? 279 PHE C CA 1 ATOM 8688 C C . PHE C 2 247 ? 45.636 34.778 2.673 1.00 44.89 ? 279 PHE C C 1 ATOM 8689 O O . PHE C 2 247 ? 45.066 33.758 3.077 1.00 38.05 ? 279 PHE C O 1 ATOM 8690 C CB . PHE C 2 247 ? 47.544 34.255 1.129 1.00 46.22 ? 279 PHE C CB 1 ATOM 8691 C CG . PHE C 2 247 ? 48.118 34.065 -0.276 1.00 47.24 ? 279 PHE C CG 1 ATOM 8692 C CD1 . PHE C 2 247 ? 47.334 34.131 -1.435 1.00 49.12 ? 279 PHE C CD1 1 ATOM 8693 C CD2 . PHE C 2 247 ? 49.479 33.775 -0.426 1.00 47.70 ? 279 PHE C CD2 1 ATOM 8694 C CE1 . PHE C 2 247 ? 47.903 33.932 -2.697 1.00 49.31 ? 279 PHE C CE1 1 ATOM 8695 C CE2 . PHE C 2 247 ? 50.050 33.588 -1.683 1.00 48.06 ? 279 PHE C CE2 1 ATOM 8696 C CZ . PHE C 2 247 ? 49.261 33.657 -2.818 1.00 48.99 ? 279 PHE C CZ 1 ATOM 8697 N N . GLN C 2 248 ? 45.911 35.821 3.468 1.00 45.93 ? 280 GLN C N 1 ATOM 8698 C CA . GLN C 2 248 ? 45.456 35.861 4.864 1.00 45.87 ? 280 GLN C CA 1 ATOM 8699 C C . GLN C 2 248 ? 43.935 35.712 4.813 1.00 46.45 ? 280 GLN C C 1 ATOM 8700 O O . GLN C 2 248 ? 43.411 34.818 5.454 1.00 45.95 ? 280 GLN C O 1 ATOM 8701 C CB . GLN C 2 248 ? 45.932 37.135 5.644 1.00 45.97 ? 280 GLN C CB 1 ATOM 8702 C CG . GLN C 2 248 ? 47.269 36.986 6.426 1.00 46.29 ? 280 GLN C CG 1 ATOM 8703 C CD . GLN C 2 248 ? 47.971 38.300 6.917 1.00 45.42 ? 280 GLN C CD 1 ATOM 8704 O OE1 . GLN C 2 248 ? 47.632 39.413 6.511 1.00 43.65 ? 280 GLN C OE1 1 ATOM 8705 N NE2 . GLN C 2 248 ? 48.977 38.145 7.792 1.00 42.94 ? 280 GLN C NE2 1 ATOM 8706 N N . LYS C 2 249 ? 43.255 36.511 3.977 1.00 49.23 ? 281 LYS C N 1 ATOM 8707 C CA . LYS C 2 249 ? 41.763 36.568 3.935 1.00 49.17 ? 281 LYS C CA 1 ATOM 8708 C C . LYS C 2 249 ? 41.081 35.288 3.469 1.00 46.43 ? 281 LYS C C 1 ATOM 8709 O O . LYS C 2 249 ? 40.017 34.943 3.942 1.00 44.40 ? 281 LYS C O 1 ATOM 8710 C CB . LYS C 2 249 ? 41.269 37.742 3.069 1.00 51.06 ? 281 LYS C CB 1 ATOM 8711 C CG . LYS C 2 249 ? 41.683 39.142 3.562 1.00 53.02 ? 281 LYS C CG 1 ATOM 8712 C CD . LYS C 2 249 ? 40.923 40.303 2.890 1.00 56.80 ? 281 LYS C CD 1 ATOM 8713 C CE . LYS C 2 249 ? 40.561 40.118 1.389 1.00 58.87 ? 281 LYS C CE 1 ATOM 8714 N NZ . LYS C 2 249 ? 41.602 40.517 0.388 1.00 56.78 1 281 LYS C NZ 1 ATOM 8715 N N . TYR C 2 250 ? 41.707 34.579 2.551 1.00 50.11 ? 282 TYR C N 1 ATOM 8716 C CA . TYR C 2 250 ? 41.136 33.360 2.004 1.00 54.49 ? 282 TYR C CA 1 ATOM 8717 C C . TYR C 2 250 ? 41.917 32.085 2.375 1.00 54.44 ? 282 TYR C C 1 ATOM 8718 O O . TYR C 2 250 ? 41.990 31.149 1.580 1.00 53.99 ? 282 TYR C O 1 ATOM 8719 C CB . TYR C 2 250 ? 41.084 33.504 0.487 1.00 58.40 ? 282 TYR C CB 1 ATOM 8720 C CG . TYR C 2 250 ? 40.187 34.608 0.022 1.00 62.20 ? 282 TYR C CG 1 ATOM 8721 C CD1 . TYR C 2 250 ? 38.838 34.359 -0.217 1.00 64.46 ? 282 TYR C CD1 1 ATOM 8722 C CD2 . TYR C 2 250 ? 40.675 35.901 -0.176 1.00 64.22 ? 282 TYR C CD2 1 ATOM 8723 C CE1 . TYR C 2 250 ? 37.989 35.362 -0.644 1.00 66.41 ? 282 TYR C CE1 1 ATOM 8724 C CE2 . TYR C 2 250 ? 39.836 36.919 -0.600 1.00 69.58 ? 282 TYR C CE2 1 ATOM 8725 C CZ . TYR C 2 250 ? 38.492 36.638 -0.837 1.00 70.10 ? 282 TYR C CZ 1 ATOM 8726 O OH . TYR C 2 250 ? 37.642 37.622 -1.275 1.00 68.94 ? 282 TYR C OH 1 ATOM 8727 N N . SER C 2 251 ? 42.486 32.034 3.577 1.00 54.37 ? 283 SER C N 1 ATOM 8728 C CA . SER C 2 251 ? 43.332 30.895 3.985 1.00 54.63 ? 283 SER C CA 1 ATOM 8729 C C . SER C 2 251 ? 42.524 29.625 4.242 1.00 55.82 ? 283 SER C C 1 ATOM 8730 O O . SER C 2 251 ? 43.042 28.483 4.148 1.00 51.88 ? 283 SER C O 1 ATOM 8731 C CB . SER C 2 251 ? 44.087 31.248 5.253 1.00 55.28 ? 283 SER C CB 1 ATOM 8732 O OG . SER C 2 251 ? 43.168 31.535 6.287 1.00 56.22 ? 283 SER C OG 1 ATOM 8733 N N . ASP C 2 252 ? 41.264 29.852 4.615 1.00 55.78 ? 284 ASP C N 1 ATOM 8734 C CA . ASP C 2 252 ? 40.258 28.802 4.702 1.00 54.25 ? 284 ASP C CA 1 ATOM 8735 C C . ASP C 2 252 ? 40.203 27.959 3.403 1.00 49.83 ? 284 ASP C C 1 ATOM 8736 O O . ASP C 2 252 ? 40.200 26.729 3.467 1.00 47.60 ? 284 ASP C O 1 ATOM 8737 C CB . ASP C 2 252 ? 38.871 29.383 5.105 1.00 57.93 ? 284 ASP C CB 1 ATOM 8738 C CG . ASP C 2 252 ? 38.612 30.820 4.569 1.00 61.39 ? 284 ASP C CG 1 ATOM 8739 O OD1 . ASP C 2 252 ? 39.335 31.780 4.950 1.00 58.00 ? 284 ASP C OD1 1 ATOM 8740 O OD2 . ASP C 2 252 ? 37.648 30.988 3.787 1.00 65.18 -1 284 ASP C OD2 1 ATOM 8741 N N . VAL C 2 253 ? 40.249 28.620 2.239 1.00 47.31 ? 285 VAL C N 1 ATOM 8742 C CA . VAL C 2 253 ? 40.109 27.955 0.904 1.00 43.97 ? 285 VAL C CA 1 ATOM 8743 C C . VAL C 2 253 ? 41.379 27.247 0.361 1.00 39.57 ? 285 VAL C C 1 ATOM 8744 O O . VAL C 2 253 ? 41.283 26.171 -0.258 1.00 35.00 ? 285 VAL C O 1 ATOM 8745 C CB . VAL C 2 253 ? 39.664 28.954 -0.202 1.00 44.81 ? 285 VAL C CB 1 ATOM 8746 C CG1 . VAL C 2 253 ? 38.815 28.223 -1.238 1.00 45.10 ? 285 VAL C CG1 1 ATOM 8747 C CG2 . VAL C 2 253 ? 38.902 30.155 0.362 1.00 45.39 ? 285 VAL C CG2 1 ATOM 8748 N N . ILE C 2 254 ? 42.541 27.875 0.608 1.00 36.39 ? 286 ILE C N 1 ATOM 8749 C CA . ILE C 2 254 ? 43.846 27.474 0.077 1.00 32.81 ? 286 ILE C CA 1 ATOM 8750 C C . ILE C 2 254 ? 44.358 26.312 0.859 1.00 32.40 ? 286 ILE C C 1 ATOM 8751 O O . ILE C 2 254 ? 44.598 26.435 2.057 1.00 31.68 ? 286 ILE C O 1 ATOM 8752 C CB . ILE C 2 254 ? 44.876 28.595 0.242 1.00 31.32 ? 286 ILE C CB 1 ATOM 8753 C CG1 . ILE C 2 254 ? 44.352 29.857 -0.412 1.00 31.83 ? 286 ILE C CG1 1 ATOM 8754 C CG2 . ILE C 2 254 ? 46.229 28.203 -0.362 1.00 30.39 ? 286 ILE C CG2 1 ATOM 8755 C CD1 . ILE C 2 254 ? 45.106 31.096 -0.010 1.00 32.77 ? 286 ILE C CD1 1 ATOM 8756 N N . ALA C 2 255 ? 44.527 25.187 0.185 1.00 33.37 ? 287 ALA C N 1 ATOM 8757 C CA . ALA C 2 255 ? 44.929 23.974 0.864 1.00 37.03 ? 287 ALA C CA 1 ATOM 8758 C C . ALA C 2 255 ? 46.403 23.694 0.671 1.00 39.11 ? 287 ALA C C 1 ATOM 8759 O O . ALA C 2 255 ? 46.869 22.630 1.049 1.00 43.18 ? 287 ALA C O 1 ATOM 8760 C CB . ALA C 2 255 ? 44.092 22.787 0.406 1.00 37.11 ? 287 ALA C CB 1 ATOM 8761 N N . GLY C 2 256 ? 47.139 24.638 0.094 1.00 41.04 ? 288 GLY C N 1 ATOM 8762 C CA . GLY C 2 256 ? 48.610 24.561 0.060 1.00 41.57 ? 288 GLY C CA 1 ATOM 8763 C C . GLY C 2 256 ? 49.201 25.404 -1.051 1.00 40.77 ? 288 GLY C C 1 ATOM 8764 O O . GLY C 2 256 ? 48.489 25.799 -1.971 1.00 39.85 ? 288 GLY C O 1 ATOM 8765 N N . GLN C 2 257 ? 50.497 25.694 -0.972 1.00 40.06 ? 289 GLN C N 1 ATOM 8766 C CA . GLN C 2 257 ? 51.104 26.624 -1.933 1.00 38.97 ? 289 GLN C CA 1 ATOM 8767 C C . GLN C 2 257 ? 52.435 26.131 -2.439 1.00 37.33 ? 289 GLN C C 1 ATOM 8768 O O . GLN C 2 257 ? 53.227 25.607 -1.669 1.00 37.11 ? 289 GLN C O 1 ATOM 8769 C CB . GLN C 2 257 ? 51.255 28.001 -1.320 1.00 37.51 ? 289 GLN C CB 1 ATOM 8770 C CG . GLN C 2 257 ? 49.923 28.624 -1.013 1.00 37.06 ? 289 GLN C CG 1 ATOM 8771 C CD . GLN C 2 257 ? 50.079 30.030 -0.548 1.00 37.41 ? 289 GLN C CD 1 ATOM 8772 O OE1 . GLN C 2 257 ? 50.489 30.903 -1.308 1.00 37.81 ? 289 GLN C OE1 1 ATOM 8773 N NE2 . GLN C 2 257 ? 49.742 30.270 0.706 1.00 38.35 ? 289 GLN C NE2 1 ATOM 8774 N N . PHE C 2 258 ? 52.667 26.332 -3.738 1.00 36.42 ? 290 PHE C N 1 ATOM 8775 C CA . PHE C 2 258 ? 53.734 25.668 -4.473 1.00 33.98 ? 290 PHE C CA 1 ATOM 8776 C C . PHE C 2 258 ? 54.457 26.689 -5.344 1.00 31.42 ? 290 PHE C C 1 ATOM 8777 O O . PHE C 2 258 ? 53.825 27.468 -6.059 1.00 27.46 ? 290 PHE C O 1 ATOM 8778 C CB . PHE C 2 258 ? 53.136 24.517 -5.291 1.00 34.81 ? 290 PHE C CB 1 ATOM 8779 C CG . PHE C 2 258 ? 52.287 23.590 -4.468 1.00 36.16 ? 290 PHE C CG 1 ATOM 8780 C CD1 . PHE C 2 258 ? 52.875 22.670 -3.596 1.00 39.29 ? 290 PHE C CD1 1 ATOM 8781 C CD2 . PHE C 2 258 ? 50.907 23.673 -4.502 1.00 36.22 ? 290 PHE C CD2 1 ATOM 8782 C CE1 . PHE C 2 258 ? 52.081 21.838 -2.794 1.00 40.02 ? 290 PHE C CE1 1 ATOM 8783 C CE2 . PHE C 2 258 ? 50.122 22.845 -3.722 1.00 36.96 ? 290 PHE C CE2 1 ATOM 8784 C CZ . PHE C 2 258 ? 50.701 21.931 -2.866 1.00 38.14 ? 290 PHE C CZ 1 ATOM 8785 N N . TYR C 2 259 ? 55.787 26.701 -5.233 1.00 30.84 ? 291 TYR C N 1 ATOM 8786 C CA . TYR C 2 259 ? 56.634 27.681 -5.930 1.00 29.63 ? 291 TYR C CA 1 ATOM 8787 C C . TYR C 2 259 ? 58.007 27.111 -6.228 1.00 27.68 ? 291 TYR C C 1 ATOM 8788 O O . TYR C 2 259 ? 58.408 26.097 -5.688 1.00 26.69 ? 291 TYR C O 1 ATOM 8789 C CB . TYR C 2 259 ? 56.871 28.939 -5.098 1.00 30.03 ? 291 TYR C CB 1 ATOM 8790 C CG . TYR C 2 259 ? 55.672 29.680 -4.575 1.00 31.58 ? 291 TYR C CG 1 ATOM 8791 C CD1 . TYR C 2 259 ? 55.039 30.633 -5.344 1.00 31.71 ? 291 TYR C CD1 1 ATOM 8792 C CD2 . TYR C 2 259 ? 55.217 29.475 -3.261 1.00 32.84 ? 291 TYR C CD2 1 ATOM 8793 C CE1 . TYR C 2 259 ? 53.947 31.336 -4.845 1.00 34.31 ? 291 TYR C CE1 1 ATOM 8794 C CE2 . TYR C 2 259 ? 54.131 30.173 -2.743 1.00 33.17 ? 291 TYR C CE2 1 ATOM 8795 C CZ . TYR C 2 259 ? 53.486 31.113 -3.534 1.00 34.85 ? 291 TYR C CZ 1 ATOM 8796 O OH . TYR C 2 259 ? 52.393 31.848 -3.040 1.00 34.16 ? 291 TYR C OH 1 ATOM 8797 N N . GLY C 2 260 ? 58.742 27.806 -7.079 1.00 27.25 ? 292 GLY C N 1 ATOM 8798 C CA . GLY C 2 260 ? 60.068 27.377 -7.478 1.00 25.84 ? 292 GLY C CA 1 ATOM 8799 C C . GLY C 2 260 ? 60.953 28.569 -7.334 1.00 24.80 ? 292 GLY C C 1 ATOM 8800 O O . GLY C 2 260 ? 61.097 29.108 -6.239 1.00 22.75 ? 292 GLY C O 1 ATOM 8801 N N . HIS C 2 261 ? 61.551 28.973 -8.445 1.00 25.58 ? 293 HIS C N 1 ATOM 8802 C CA . HIS C 2 261 ? 62.372 30.195 -8.519 1.00 26.10 ? 293 HIS C CA 1 ATOM 8803 C C . HIS C 2 261 ? 63.670 30.176 -7.616 1.00 25.83 ? 293 HIS C C 1 ATOM 8804 O O . HIS C 2 261 ? 64.772 30.299 -8.177 1.00 26.22 ? 293 HIS C O 1 ATOM 8805 C CB . HIS C 2 261 ? 61.453 31.449 -8.338 1.00 26.45 ? 293 HIS C CB 1 ATOM 8806 C CG . HIS C 2 261 ? 62.164 32.768 -8.359 1.00 25.29 ? 293 HIS C CG 1 ATOM 8807 N ND1 . HIS C 2 261 ? 63.152 33.071 -9.262 1.00 25.01 ? 293 HIS C ND1 1 ATOM 8808 C CD2 . HIS C 2 261 ? 62.006 33.871 -7.594 1.00 25.62 ? 293 HIS C CD2 1 ATOM 8809 C CE1 . HIS C 2 261 ? 63.601 34.290 -9.038 1.00 25.34 ? 293 HIS C CE1 1 ATOM 8810 N NE2 . HIS C 2 261 ? 62.912 34.805 -8.038 1.00 26.34 ? 293 HIS C NE2 1 ATOM 8811 N N A THR C 2 262 ? 63.565 30.007 -6.278 0.50 24.68 ? 294 THR C N 1 ATOM 8812 N N B THR C 2 262 ? 63.511 30.001 -6.295 0.50 24.73 ? 294 THR C N 1 ATOM 8813 C CA A THR C 2 262 ? 64.769 30.041 -5.403 0.50 22.78 ? 294 THR C CA 1 ATOM 8814 C CA B THR C 2 262 ? 64.617 30.002 -5.330 0.50 22.69 ? 294 THR C CA 1 ATOM 8815 C C A THR C 2 262 ? 65.796 28.951 -5.736 0.50 22.50 ? 294 THR C C 1 ATOM 8816 C C B THR C 2 262 ? 65.711 28.930 -5.643 0.50 22.49 ? 294 THR C C 1 ATOM 8817 O O A THR C 2 262 ? 66.977 29.101 -5.438 0.50 21.54 ? 294 THR C O 1 ATOM 8818 O O B THR C 2 262 ? 66.863 29.094 -5.262 0.50 21.69 ? 294 THR C O 1 ATOM 8819 C CB A THR C 2 262 ? 64.452 30.004 -3.885 0.50 21.82 ? 294 THR C CB 1 ATOM 8820 C CB B THR C 2 262 ? 64.028 29.937 -3.889 0.50 21.69 ? 294 THR C CB 1 ATOM 8821 O OG1 A THR C 2 262 ? 64.140 28.669 -3.476 0.50 20.67 ? 294 THR C OG1 1 ATOM 8822 O OG1 B THR C 2 262 ? 63.635 31.257 -3.452 0.50 20.90 ? 294 THR C OG1 1 ATOM 8823 C CG2 A THR C 2 262 ? 63.319 30.995 -3.525 0.50 21.53 ? 294 THR C CG2 1 ATOM 8824 C CG2 B THR C 2 262 ? 65.000 29.365 -2.922 0.50 21.11 ? 294 THR C CG2 1 ATOM 8825 N N . HIS C 2 263 ? 65.346 27.894 -6.410 1.00 23.21 ? 295 HIS C N 1 ATOM 8826 C CA . HIS C 2 263 ? 66.183 26.698 -6.722 1.00 23.88 ? 295 HIS C CA 1 ATOM 8827 C C . HIS C 2 263 ? 66.505 25.942 -5.400 1.00 25.23 ? 295 HIS C C 1 ATOM 8828 O O . HIS C 2 263 ? 67.438 25.123 -5.308 1.00 24.28 ? 295 HIS C O 1 ATOM 8829 C CB . HIS C 2 263 ? 67.453 27.002 -7.544 1.00 24.47 ? 295 HIS C CB 1 ATOM 8830 C CG . HIS C 2 263 ? 67.218 27.372 -8.995 1.00 25.78 ? 295 HIS C CG 1 ATOM 8831 N ND1 . HIS C 2 263 ? 68.226 27.324 -9.945 1.00 26.15 ? 295 HIS C ND1 1 ATOM 8832 C CD2 . HIS C 2 263 ? 66.121 27.822 -9.653 1.00 25.80 ? 295 HIS C CD2 1 ATOM 8833 C CE1 . HIS C 2 263 ? 67.764 27.741 -11.111 1.00 25.03 ? 295 HIS C CE1 1 ATOM 8834 N NE2 . HIS C 2 263 ? 66.487 28.032 -10.967 1.00 24.46 ? 295 HIS C NE2 1 ATOM 8835 N N . ARG C 2 264 ? 65.682 26.181 -4.380 1.00 26.33 ? 296 ARG C N 1 ATOM 8836 C CA . ARG C 2 264 ? 65.948 25.634 -3.074 1.00 26.81 ? 296 ARG C CA 1 ATOM 8837 C C . ARG C 2 264 ? 64.724 24.954 -2.498 1.00 26.77 ? 296 ARG C C 1 ATOM 8838 O O . ARG C 2 264 ? 63.586 25.246 -2.881 1.00 25.17 ? 296 ARG C O 1 ATOM 8839 C CB . ARG C 2 264 ? 66.468 26.706 -2.093 1.00 26.83 ? 296 ARG C CB 1 ATOM 8840 C CG . ARG C 2 264 ? 67.699 27.444 -2.579 1.00 26.76 ? 296 ARG C CG 1 ATOM 8841 C CD . ARG C 2 264 ? 68.917 26.534 -2.558 1.00 27.55 ? 296 ARG C CD 1 ATOM 8842 N NE . ARG C 2 264 ? 70.120 27.133 -3.166 1.00 28.55 ? 296 ARG C NE 1 ATOM 8843 C CZ . ARG C 2 264 ? 70.601 26.854 -4.384 1.00 29.10 ? 296 ARG C CZ 1 ATOM 8844 N NH1 . ARG C 2 264 ? 70.005 25.992 -5.213 1.00 30.89 1 296 ARG C NH1 1 ATOM 8845 N NH2 . ARG C 2 264 ? 71.701 27.447 -4.789 1.00 29.26 ? 296 ARG C NH2 1 ATOM 8846 N N . ASP C 2 265 ? 65.020 24.041 -1.568 1.00 26.99 ? 297 ASP C N 1 ATOM 8847 C CA . ASP C 2 265 ? 64.045 23.326 -0.784 1.00 27.77 ? 297 ASP C CA 1 ATOM 8848 C C . ASP C 2 265 ? 63.751 24.096 0.501 1.00 27.65 ? 297 ASP C C 1 ATOM 8849 O O . ASP C 2 265 ? 64.387 23.871 1.558 1.00 26.34 ? 297 ASP C O 1 ATOM 8850 C CB . ASP C 2 265 ? 64.580 21.933 -0.463 1.00 28.78 ? 297 ASP C CB 1 ATOM 8851 C CG . ASP C 2 265 ? 63.566 21.071 0.284 1.00 29.39 ? 297 ASP C CG 1 ATOM 8852 O OD1 . ASP C 2 265 ? 62.752 21.613 1.052 1.00 33.18 ? 297 ASP C OD1 1 ATOM 8853 O OD2 . ASP C 2 265 ? 63.582 19.842 0.127 1.00 28.94 -1 297 ASP C OD2 1 ATOM 8854 N N . SER C 2 266 ? 62.764 24.988 0.396 1.00 28.59 ? 298 SER C N 1 ATOM 8855 C CA . SER C 2 266 ? 62.325 25.838 1.515 1.00 30.26 ? 298 SER C CA 1 ATOM 8856 C C . SER C 2 266 ? 60.856 25.609 1.912 1.00 30.02 ? 298 SER C C 1 ATOM 8857 O O . SER C 2 266 ? 60.037 25.261 1.062 1.00 32.02 ? 298 SER C O 1 ATOM 8858 C CB . SER C 2 266 ? 62.542 27.317 1.160 1.00 30.35 ? 298 SER C CB 1 ATOM 8859 O OG . SER C 2 266 ? 63.862 27.747 1.472 1.00 30.96 ? 298 SER C OG 1 ATOM 8860 N N . ILE C 2 267 ? 60.537 25.764 3.199 1.00 29.68 ? 299 ILE C N 1 ATOM 8861 C CA . ILE C 2 267 ? 59.127 25.792 3.664 1.00 30.02 ? 299 ILE C CA 1 ATOM 8862 C C . ILE C 2 267 ? 58.798 27.194 4.161 1.00 30.19 ? 299 ILE C C 1 ATOM 8863 O O . ILE C 2 267 ? 59.679 27.908 4.632 1.00 30.66 ? 299 ILE C O 1 ATOM 8864 C CB . ILE C 2 267 ? 58.804 24.766 4.794 1.00 29.11 ? 299 ILE C CB 1 ATOM 8865 C CG1 . ILE C 2 267 ? 59.373 25.210 6.155 1.00 28.86 ? 299 ILE C CG1 1 ATOM 8866 C CG2 . ILE C 2 267 ? 59.340 23.394 4.444 1.00 29.33 ? 299 ILE C CG2 1 ATOM 8867 C CD1 . ILE C 2 267 ? 58.573 24.731 7.347 1.00 28.20 ? 299 ILE C CD1 1 ATOM 8868 N N . MET C 2 268 ? 57.539 27.591 4.031 1.00 30.47 ? 300 MET C N 1 ATOM 8869 C CA . MET C 2 268 ? 57.047 28.814 4.667 1.00 30.97 ? 300 MET C CA 1 ATOM 8870 C C . MET C 2 268 ? 55.715 28.536 5.288 1.00 30.08 ? 300 MET C C 1 ATOM 8871 O O . MET C 2 268 ? 54.998 27.646 4.847 1.00 28.47 ? 300 MET C O 1 ATOM 8872 C CB . MET C 2 268 ? 56.902 29.981 3.690 1.00 31.51 ? 300 MET C CB 1 ATOM 8873 C CG . MET C 2 268 ? 57.987 31.037 3.812 1.00 31.18 ? 300 MET C CG 1 ATOM 8874 S SD . MET C 2 268 ? 57.974 32.221 2.453 1.00 33.59 ? 300 MET C SD 1 ATOM 8875 C CE . MET C 2 268 ? 58.027 31.212 0.947 1.00 30.50 ? 300 MET C CE 1 ATOM 8876 N N . VAL C 2 269 ? 55.416 29.316 6.320 1.00 31.59 ? 301 VAL C N 1 ATOM 8877 C CA . VAL C 2 269 ? 54.189 29.190 7.087 1.00 34.62 ? 301 VAL C CA 1 ATOM 8878 C C . VAL C 2 269 ? 53.553 30.561 7.144 1.00 34.90 ? 301 VAL C C 1 ATOM 8879 O O . VAL C 2 269 ? 54.083 31.466 7.781 1.00 34.57 ? 301 VAL C O 1 ATOM 8880 C CB . VAL C 2 269 ? 54.433 28.646 8.531 1.00 36.47 ? 301 VAL C CB 1 ATOM 8881 C CG1 . VAL C 2 269 ? 53.142 28.661 9.349 1.00 36.78 ? 301 VAL C CG1 1 ATOM 8882 C CG2 . VAL C 2 269 ? 55.014 27.224 8.505 1.00 37.36 ? 301 VAL C CG2 1 ATOM 8883 N N . LEU C 2 270 ? 52.429 30.721 6.460 1.00 37.27 ? 302 LEU C N 1 ATOM 8884 C CA . LEU C 2 270 ? 51.660 31.938 6.607 1.00 43.18 ? 302 LEU C CA 1 ATOM 8885 C C . LEU C 2 270 ? 50.851 31.918 7.922 1.00 45.02 ? 302 LEU C C 1 ATOM 8886 O O . LEU C 2 270 ? 50.290 30.869 8.308 1.00 42.59 ? 302 LEU C O 1 ATOM 8887 C CB . LEU C 2 270 ? 50.732 32.139 5.410 1.00 45.44 ? 302 LEU C CB 1 ATOM 8888 C CG . LEU C 2 270 ? 49.800 33.360 5.522 1.00 46.83 ? 302 LEU C CG 1 ATOM 8889 C CD1 . LEU C 2 270 ? 50.599 34.656 5.615 1.00 45.69 ? 302 LEU C CD1 1 ATOM 8890 C CD2 . LEU C 2 270 ? 48.816 33.400 4.351 1.00 48.27 ? 302 LEU C CD2 1 ATOM 8891 N N . SER C 2 271 ? 50.807 33.080 8.589 1.00 46.74 ? 303 SER C N 1 ATOM 8892 C CA . SER C 2 271 ? 50.019 33.284 9.814 1.00 50.96 ? 303 SER C CA 1 ATOM 8893 C C . SER C 2 271 ? 48.970 34.403 9.651 1.00 54.20 ? 303 SER C C 1 ATOM 8894 O O . SER C 2 271 ? 49.185 35.341 8.882 1.00 54.81 ? 303 SER C O 1 ATOM 8895 C CB . SER C 2 271 ? 50.951 33.610 10.992 1.00 51.05 ? 303 SER C CB 1 ATOM 8896 O OG . SER C 2 271 ? 51.971 32.625 11.130 1.00 52.08 ? 303 SER C OG 1 ATOM 8897 N N . ASP C 2 272 ? 47.839 34.311 10.367 1.00 56.34 ? 304 ASP C N 1 ATOM 8898 C CA . ASP C 2 272 ? 46.819 35.367 10.299 1.00 54.41 ? 304 ASP C CA 1 ATOM 8899 C C . ASP C 2 272 ? 47.407 36.626 10.953 1.00 51.78 ? 304 ASP C C 1 ATOM 8900 O O . ASP C 2 272 ? 48.457 36.573 11.592 1.00 46.62 ? 304 ASP C O 1 ATOM 8901 C CB . ASP C 2 272 ? 45.435 34.898 10.849 1.00 56.84 ? 304 ASP C CB 1 ATOM 8902 C CG . ASP C 2 272 ? 45.375 34.739 12.387 1.00 58.33 ? 304 ASP C CG 1 ATOM 8903 O OD1 . ASP C 2 272 ? 46.231 35.276 13.106 1.00 61.91 ? 304 ASP C OD1 1 ATOM 8904 O OD2 . ASP C 2 272 ? 44.425 34.097 12.888 1.00 55.37 -1 304 ASP C OD2 1 ATOM 8905 N N . LYS C 2 273 ? 46.795 37.779 10.772 1.00 53.03 ? 305 LYS C N 1 ATOM 8906 C CA . LYS C 2 273 ? 47.443 38.950 11.321 1.00 57.60 ? 305 LYS C CA 1 ATOM 8907 C C . LYS C 2 273 ? 47.455 38.900 12.860 1.00 59.48 ? 305 LYS C C 1 ATOM 8908 O O . LYS C 2 273 ? 48.175 39.669 13.497 1.00 62.09 ? 305 LYS C O 1 ATOM 8909 C CB . LYS C 2 273 ? 46.838 40.253 10.779 1.00 61.78 ? 305 LYS C CB 1 ATOM 8910 C CG . LYS C 2 273 ? 47.881 41.358 10.487 1.00 67.45 ? 305 LYS C CG 1 ATOM 8911 C CD . LYS C 2 273 ? 48.378 42.175 11.710 1.00 68.30 ? 305 LYS C CD 1 ATOM 8912 C CE . LYS C 2 273 ? 49.831 41.901 12.116 1.00 66.10 ? 305 LYS C CE 1 ATOM 8913 N NZ . LYS C 2 273 ? 50.855 42.396 11.144 1.00 65.91 1 305 LYS C NZ 1 ATOM 8914 N N . LYS C 2 274 ? 46.688 37.987 13.459 1.00 61.96 ? 306 LYS C N 1 ATOM 8915 C CA . LYS C 2 274 ? 46.772 37.750 14.917 1.00 62.83 ? 306 LYS C CA 1 ATOM 8916 C C . LYS C 2 274 ? 48.060 36.990 15.332 1.00 57.80 ? 306 LYS C C 1 ATOM 8917 O O . LYS C 2 274 ? 48.564 37.200 16.423 1.00 55.71 ? 306 LYS C O 1 ATOM 8918 C CB . LYS C 2 274 ? 45.496 37.039 15.444 1.00 66.18 ? 306 LYS C CB 1 ATOM 8919 C CG . LYS C 2 274 ? 45.129 37.301 16.920 1.00 66.45 ? 306 LYS C CG 1 ATOM 8920 C CD . LYS C 2 274 ? 44.722 38.752 17.231 1.00 65.01 ? 306 LYS C CD 1 ATOM 8921 C CE . LYS C 2 274 ? 45.816 39.550 17.959 1.00 63.52 ? 306 LYS C CE 1 ATOM 8922 N NZ . LYS C 2 274 ? 46.009 39.166 19.395 1.00 59.49 1 306 LYS C NZ 1 ATOM 8923 N N . GLY C 2 275 ? 48.594 36.129 14.466 1.00 56.32 ? 307 GLY C N 1 ATOM 8924 C CA . GLY C 2 275 ? 49.879 35.442 14.723 1.00 54.45 ? 307 GLY C CA 1 ATOM 8925 C C . GLY C 2 275 ? 49.825 33.921 14.792 1.00 54.95 ? 307 GLY C C 1 ATOM 8926 O O . GLY C 2 275 ? 50.760 33.259 15.269 1.00 56.48 ? 307 GLY C O 1 ATOM 8927 N N . SER C 2 276 ? 48.733 33.352 14.308 1.00 55.10 ? 308 SER C N 1 ATOM 8928 C CA . SER C 2 276 ? 48.496 31.926 14.443 1.00 54.91 ? 308 SER C CA 1 ATOM 8929 C C . SER C 2 276 ? 48.788 31.301 13.077 1.00 50.75 ? 308 SER C C 1 ATOM 8930 O O . SER C 2 276 ? 48.393 31.882 12.070 1.00 49.56 ? 308 SER C O 1 ATOM 8931 C CB . SER C 2 276 ? 47.029 31.694 14.872 1.00 55.38 ? 308 SER C CB 1 ATOM 8932 O OG . SER C 2 276 ? 46.896 30.593 15.766 1.00 56.47 ? 308 SER C OG 1 ATOM 8933 N N . PRO C 2 277 ? 49.469 30.127 13.036 1.00 46.62 ? 309 PRO C N 1 ATOM 8934 C CA . PRO C 2 277 ? 49.731 29.461 11.748 1.00 43.02 ? 309 PRO C CA 1 ATOM 8935 C C . PRO C 2 277 ? 48.445 29.098 11.007 1.00 39.57 ? 309 PRO C C 1 ATOM 8936 O O . PRO C 2 277 ? 47.552 28.504 11.617 1.00 35.12 ? 309 PRO C O 1 ATOM 8937 C CB . PRO C 2 277 ? 50.488 28.190 12.154 1.00 44.89 ? 309 PRO C CB 1 ATOM 8938 C CG . PRO C 2 277 ? 50.073 27.918 13.573 1.00 47.38 ? 309 PRO C CG 1 ATOM 8939 C CD . PRO C 2 277 ? 49.893 29.289 14.181 1.00 48.37 ? 309 PRO C CD 1 ATOM 8940 N N . VAL C 2 278 ? 48.350 29.473 9.723 1.00 38.34 ? 310 VAL C N 1 ATOM 8941 C CA . VAL C 2 278 ? 47.118 29.252 8.933 1.00 37.96 ? 310 VAL C CA 1 ATOM 8942 C C . VAL C 2 278 ? 47.295 28.633 7.544 1.00 37.33 ? 310 VAL C C 1 ATOM 8943 O O . VAL C 2 278 ? 46.306 28.215 6.965 1.00 37.72 ? 310 VAL C O 1 ATOM 8944 C CB . VAL C 2 278 ? 46.253 30.543 8.773 1.00 38.32 ? 310 VAL C CB 1 ATOM 8945 C CG1 . VAL C 2 278 ? 45.743 31.028 10.118 1.00 38.80 ? 310 VAL C CG1 1 ATOM 8946 C CG2 . VAL C 2 278 ? 47.004 31.667 8.056 1.00 38.25 ? 310 VAL C CG2 1 ATOM 8947 N N . ASN C 2 279 ? 48.514 28.572 7.001 1.00 37.20 ? 311 ASN C N 1 ATOM 8948 C CA . ASN C 2 279 ? 48.722 27.999 5.651 1.00 36.48 ? 311 ASN C CA 1 ATOM 8949 C C . ASN C 2 279 ? 50.148 27.502 5.480 1.00 36.39 ? 311 ASN C C 1 ATOM 8950 O O . ASN C 2 279 ? 51.056 28.039 6.111 1.00 39.48 ? 311 ASN C O 1 ATOM 8951 C CB . ASN C 2 279 ? 48.437 29.050 4.584 1.00 35.95 ? 311 ASN C CB 1 ATOM 8952 C CG . ASN C 2 279 ? 47.821 28.458 3.360 1.00 35.55 ? 311 ASN C CG 1 ATOM 8953 O OD1 . ASN C 2 279 ? 48.469 27.712 2.595 1.00 35.28 ? 311 ASN C OD1 1 ATOM 8954 N ND2 . ASN C 2 279 ? 46.545 28.748 3.179 1.00 34.58 ? 311 ASN C ND2 1 ATOM 8955 N N . SER C 2 280 ? 50.355 26.474 4.661 1.00 33.14 ? 312 SER C N 1 ATOM 8956 C CA . SER C 2 280 ? 51.720 26.025 4.387 1.00 30.12 ? 312 SER C CA 1 ATOM 8957 C C . SER C 2 280 ? 52.068 26.298 2.937 1.00 31.11 ? 312 SER C C 1 ATOM 8958 O O . SER C 2 280 ? 51.212 26.216 2.012 1.00 29.85 ? 312 SER C O 1 ATOM 8959 C CB . SER C 2 280 ? 51.923 24.550 4.708 1.00 28.61 ? 312 SER C CB 1 ATOM 8960 O OG . SER C 2 280 ? 51.737 24.329 6.071 1.00 26.24 ? 312 SER C OG 1 ATOM 8961 N N . LEU C 2 281 ? 53.343 26.649 2.775 1.00 31.08 ? 313 LEU C N 1 ATOM 8962 C CA . LEU C 2 281 ? 53.937 27.010 1.487 1.00 30.67 ? 313 LEU C CA 1 ATOM 8963 C C . LEU C 2 281 ? 55.174 26.154 1.266 1.00 29.02 ? 313 LEU C C 1 ATOM 8964 O O . LEU C 2 281 ? 55.882 25.801 2.227 1.00 29.82 ? 313 LEU C O 1 ATOM 8965 C CB . LEU C 2 281 ? 54.319 28.495 1.424 1.00 29.83 ? 313 LEU C CB 1 ATOM 8966 C CG . LEU C 2 281 ? 53.130 29.453 1.372 1.00 29.90 ? 313 LEU C CG 1 ATOM 8967 C CD1 . LEU C 2 281 ? 52.573 29.675 2.762 1.00 31.18 ? 313 LEU C CD1 1 ATOM 8968 C CD2 . LEU C 2 281 ? 53.515 30.793 0.780 1.00 30.49 ? 313 LEU C CD2 1 ATOM 8969 N N . PHE C 2 282 ? 55.405 25.823 -0.004 1.00 26.58 ? 314 PHE C N 1 ATOM 8970 C CA . PHE C 2 282 ? 56.413 24.868 -0.403 1.00 25.35 ? 314 PHE C CA 1 ATOM 8971 C C . PHE C 2 282 ? 57.111 25.326 -1.652 1.00 23.96 ? 314 PHE C C 1 ATOM 8972 O O . PHE C 2 282 ? 56.565 25.304 -2.759 1.00 21.77 ? 314 PHE C O 1 ATOM 8973 C CB . PHE C 2 282 ? 55.797 23.511 -0.653 1.00 26.12 ? 314 PHE C CB 1 ATOM 8974 C CG . PHE C 2 282 ? 55.203 22.907 0.567 1.00 27.39 ? 314 PHE C CG 1 ATOM 8975 C CD1 . PHE C 2 282 ? 55.990 22.127 1.427 1.00 27.20 ? 314 PHE C CD1 1 ATOM 8976 C CD2 . PHE C 2 282 ? 53.848 23.138 0.878 1.00 28.31 ? 314 PHE C CD2 1 ATOM 8977 C CE1 . PHE C 2 282 ? 55.428 21.584 2.561 1.00 28.11 ? 314 PHE C CE1 1 ATOM 8978 C CE2 . PHE C 2 282 ? 53.284 22.608 2.021 1.00 28.30 ? 314 PHE C CE2 1 ATOM 8979 C CZ . PHE C 2 282 ? 54.074 21.830 2.863 1.00 29.03 ? 314 PHE C CZ 1 ATOM 8980 N N . VAL C 2 283 ? 58.343 25.743 -1.424 1.00 24.01 ? 315 VAL C N 1 ATOM 8981 C CA . VAL C 2 283 ? 59.295 25.987 -2.463 1.00 24.06 ? 315 VAL C CA 1 ATOM 8982 C C . VAL C 2 283 ? 60.126 24.717 -2.730 1.00 24.20 ? 315 VAL C C 1 ATOM 8983 O O . VAL C 2 283 ? 60.783 24.125 -1.865 1.00 21.47 ? 315 VAL C O 1 ATOM 8984 C CB . VAL C 2 283 ? 60.192 27.187 -2.141 1.00 24.04 ? 315 VAL C CB 1 ATOM 8985 C CG1 . VAL C 2 283 ? 61.190 27.385 -3.258 1.00 24.63 ? 315 VAL C CG1 1 ATOM 8986 C CG2 . VAL C 2 283 ? 59.359 28.459 -1.924 1.00 23.68 ? 315 VAL C CG2 1 ATOM 8987 N N . ALA C 2 284 ? 60.049 24.332 -3.991 1.00 26.59 ? 316 ALA C N 1 ATOM 8988 C CA . ALA C 2 284 ? 60.718 23.186 -4.532 1.00 28.29 ? 316 ALA C CA 1 ATOM 8989 C C . ALA C 2 284 ? 62.073 23.593 -5.098 1.00 28.73 ? 316 ALA C C 1 ATOM 8990 O O . ALA C 2 284 ? 62.209 24.623 -5.759 1.00 28.79 ? 316 ALA C O 1 ATOM 8991 C CB . ALA C 2 284 ? 59.848 22.567 -5.637 1.00 29.15 ? 316 ALA C CB 1 ATOM 8992 N N . PRO C 2 285 ? 63.085 22.768 -4.859 1.00 29.45 ? 317 PRO C N 1 ATOM 8993 C CA . PRO C 2 285 ? 64.320 23.054 -5.536 1.00 29.27 ? 317 PRO C CA 1 ATOM 8994 C C . PRO C 2 285 ? 64.259 22.678 -7.007 1.00 28.17 ? 317 PRO C C 1 ATOM 8995 O O . PRO C 2 285 ? 63.391 21.906 -7.442 1.00 26.74 ? 317 PRO C O 1 ATOM 8996 C CB . PRO C 2 285 ? 65.323 22.169 -4.803 1.00 30.11 ? 317 PRO C CB 1 ATOM 8997 C CG . PRO C 2 285 ? 64.527 20.970 -4.389 1.00 30.31 ? 317 PRO C CG 1 ATOM 8998 C CD . PRO C 2 285 ? 63.124 21.474 -4.152 1.00 30.16 ? 317 PRO C CD 1 ATOM 8999 N N . ALA C 2 286 ? 65.234 23.217 -7.727 1.00 29.23 ? 318 ALA C N 1 ATOM 9000 C CA . ALA C 2 286 ? 65.324 23.144 -9.179 1.00 30.20 ? 318 ALA C CA 1 ATOM 9001 C C . ALA C 2 286 ? 65.851 21.789 -9.708 1.00 29.49 ? 318 ALA C C 1 ATOM 9002 O O . ALA C 2 286 ? 66.408 20.998 -8.942 1.00 27.31 ? 318 ALA C O 1 ATOM 9003 C CB . ALA C 2 286 ? 66.190 24.299 -9.688 1.00 29.92 ? 318 ALA C CB 1 ATOM 9004 N N . VAL C 2 287 ? 65.611 21.542 -11.010 1.00 30.32 ? 319 VAL C N 1 ATOM 9005 C CA . VAL C 2 287 ? 66.183 20.402 -11.764 1.00 31.58 ? 319 VAL C CA 1 ATOM 9006 C C . VAL C 2 287 ? 67.539 20.837 -12.327 1.00 33.03 ? 319 VAL C C 1 ATOM 9007 O O . VAL C 2 287 ? 68.495 20.022 -12.338 1.00 35.22 ? 319 VAL C O 1 ATOM 9008 C CB . VAL C 2 287 ? 65.282 19.854 -12.941 1.00 30.58 ? 319 VAL C CB 1 ATOM 9009 C CG1 . VAL C 2 287 ? 65.985 18.710 -13.710 1.00 29.22 ? 319 VAL C CG1 1 ATOM 9010 C CG2 . VAL C 2 287 ? 63.894 19.416 -12.451 1.00 29.42 ? 319 VAL C CG2 1 ATOM 9011 N N . THR C 2 288 ? 67.652 22.087 -12.792 1.00 31.65 ? 320 THR C N 1 ATOM 9012 C CA . THR C 2 288 ? 68.984 22.552 -13.107 1.00 32.98 ? 320 THR C CA 1 ATOM 9013 C C . THR C 2 288 ? 69.791 22.516 -11.810 1.00 36.38 ? 320 THR C C 1 ATOM 9014 O O . THR C 2 288 ? 69.247 22.804 -10.748 1.00 41.37 ? 320 THR C O 1 ATOM 9015 C CB . THR C 2 288 ? 69.039 23.962 -13.689 1.00 30.50 ? 320 THR C CB 1 ATOM 9016 O OG1 . THR C 2 288 ? 70.395 24.238 -14.089 1.00 28.66 ? 320 THR C OG1 1 ATOM 9017 C CG2 . THR C 2 288 ? 68.585 24.976 -12.670 1.00 29.11 ? 320 THR C CG2 1 ATOM 9018 N N . PRO C 2 289 ? 71.074 22.142 -11.887 1.00 36.76 ? 321 PRO C N 1 ATOM 9019 C CA . PRO C 2 289 ? 71.987 22.299 -10.770 1.00 37.38 ? 321 PRO C CA 1 ATOM 9020 C C . PRO C 2 289 ? 72.834 23.593 -10.854 1.00 37.93 ? 321 PRO C C 1 ATOM 9021 O O . PRO C 2 289 ? 73.752 23.784 -10.043 1.00 41.63 ? 321 PRO C O 1 ATOM 9022 C CB . PRO C 2 289 ? 72.897 21.084 -10.922 1.00 38.44 ? 321 PRO C CB 1 ATOM 9023 C CG . PRO C 2 289 ? 72.979 20.882 -12.405 1.00 39.19 ? 321 PRO C CG 1 ATOM 9024 C CD . PRO C 2 289 ? 71.733 21.482 -13.025 1.00 37.81 ? 321 PRO C CD 1 ATOM 9025 N N . VAL C 2 290 ? 72.529 24.470 -11.806 1.00 35.00 ? 322 VAL C N 1 ATOM 9026 C CA . VAL C 2 290 ? 73.428 25.560 -12.165 1.00 33.95 ? 322 VAL C CA 1 ATOM 9027 C C . VAL C 2 290 ? 73.689 26.579 -11.021 1.00 31.27 ? 322 VAL C C 1 ATOM 9028 O O . VAL C 2 290 ? 72.887 26.736 -10.113 1.00 33.46 ? 322 VAL C O 1 ATOM 9029 C CB . VAL C 2 290 ? 72.874 26.251 -13.434 1.00 36.76 ? 322 VAL C CB 1 ATOM 9030 C CG1 . VAL C 2 290 ? 71.701 27.159 -13.086 1.00 38.53 ? 322 VAL C CG1 1 ATOM 9031 C CG2 . VAL C 2 290 ? 73.957 27.012 -14.184 1.00 37.59 ? 322 VAL C CG2 1 ATOM 9032 N N . LYS C 2 291 ? 74.825 27.261 -11.060 1.00 28.35 ? 323 LYS C N 1 ATOM 9033 C CA . LYS C 2 291 ? 75.154 28.265 -10.065 1.00 27.55 ? 323 LYS C CA 1 ATOM 9034 C C . LYS C 2 291 ? 76.243 29.180 -10.581 1.00 27.26 ? 323 LYS C C 1 ATOM 9035 O O . LYS C 2 291 ? 76.737 28.999 -11.715 1.00 28.80 ? 323 LYS C O 1 ATOM 9036 C CB . LYS C 2 291 ? 75.608 27.605 -8.784 1.00 29.06 ? 323 LYS C CB 1 ATOM 9037 C CG . LYS C 2 291 ? 76.807 26.705 -8.952 1.00 30.90 ? 323 LYS C CG 1 ATOM 9038 C CD . LYS C 2 291 ? 77.734 26.722 -7.756 1.00 31.45 ? 323 LYS C CD 1 ATOM 9039 C CE . LYS C 2 291 ? 79.006 25.984 -8.106 1.00 32.15 ? 323 LYS C CE 1 ATOM 9040 N NZ . LYS C 2 291 ? 80.179 26.845 -7.833 1.00 32.80 1 323 LYS C NZ 1 ATOM 9041 N N . SER C 2 292 ? 76.594 30.185 -9.785 1.00 25.99 ? 324 SER C N 1 ATOM 9042 C CA A SER C 2 292 ? 77.674 31.102 -10.151 0.50 26.52 ? 324 SER C CA 1 ATOM 9043 C CA B SER C 2 292 ? 77.660 31.093 -10.162 0.50 26.35 ? 324 SER C CA 1 ATOM 9044 C C . SER C 2 292 ? 79.026 30.449 -9.930 1.00 26.89 ? 324 SER C C 1 ATOM 9045 O O . SER C 2 292 ? 79.160 29.427 -9.228 1.00 24.38 ? 324 SER C O 1 ATOM 9046 C CB A SER C 2 292 ? 77.646 32.390 -9.319 0.50 27.07 ? 324 SER C CB 1 ATOM 9047 C CB B SER C 2 292 ? 77.554 32.389 -9.362 0.50 26.71 ? 324 SER C CB 1 ATOM 9048 O OG A SER C 2 292 ? 76.571 33.242 -9.650 0.50 27.67 ? 324 SER C OG 1 ATOM 9049 O OG B SER C 2 292 ? 78.535 33.327 -9.758 0.50 26.90 ? 324 SER C OG 1 ATOM 9050 N N . VAL C 2 293 ? 80.043 31.063 -10.512 1.00 28.67 ? 325 VAL C N 1 ATOM 9051 C CA . VAL C 2 293 ? 81.393 30.621 -10.279 1.00 29.75 ? 325 VAL C CA 1 ATOM 9052 C C . VAL C 2 293 ? 81.789 30.937 -8.841 1.00 32.18 ? 325 VAL C C 1 ATOM 9053 O O . VAL C 2 293 ? 82.521 30.148 -8.222 1.00 31.90 ? 325 VAL C O 1 ATOM 9054 C CB . VAL C 2 293 ? 82.357 31.323 -11.216 1.00 28.40 ? 325 VAL C CB 1 ATOM 9055 C CG1 . VAL C 2 293 ? 83.777 30.872 -10.904 1.00 29.02 ? 325 VAL C CG1 1 ATOM 9056 C CG2 . VAL C 2 293 ? 81.983 30.989 -12.641 1.00 28.98 ? 325 VAL C CG2 1 ATOM 9057 N N . LEU C 2 294 ? 81.313 32.097 -8.341 1.00 33.14 ? 326 LEU C N 1 ATOM 9058 C CA . LEU C 2 294 ? 81.661 32.636 -7.003 1.00 33.05 ? 326 LEU C CA 1 ATOM 9059 C C . LEU C 2 294 ? 80.865 31.981 -5.850 1.00 36.85 ? 326 LEU C C 1 ATOM 9060 O O . LEU C 2 294 ? 81.168 32.227 -4.662 1.00 39.83 ? 326 LEU C O 1 ATOM 9061 C CB . LEU C 2 294 ? 81.503 34.181 -6.964 1.00 29.89 ? 326 LEU C CB 1 ATOM 9062 C CG . LEU C 2 294 ? 82.453 34.966 -7.896 1.00 29.84 ? 326 LEU C CG 1 ATOM 9063 C CD1 . LEU C 2 294 ? 82.291 36.473 -7.771 1.00 29.90 ? 326 LEU C CD1 1 ATOM 9064 C CD2 . LEU C 2 294 ? 83.920 34.601 -7.677 1.00 28.64 ? 326 LEU C CD2 1 ATOM 9065 N N . GLU C 2 295 ? 79.872 31.147 -6.188 1.00 36.37 ? 327 GLU C N 1 ATOM 9066 C CA . GLU C 2 295 ? 79.030 30.490 -5.189 1.00 37.22 ? 327 GLU C CA 1 ATOM 9067 C C . GLU C 2 295 ? 79.557 29.068 -4.833 1.00 39.83 ? 327 GLU C C 1 ATOM 9068 O O . GLU C 2 295 ? 79.702 28.204 -5.701 1.00 41.21 ? 327 GLU C O 1 ATOM 9069 C CB . GLU C 2 295 ? 77.581 30.423 -5.709 1.00 38.26 ? 327 GLU C CB 1 ATOM 9070 C CG . GLU C 2 295 ? 76.823 31.750 -5.735 1.00 39.34 ? 327 GLU C CG 1 ATOM 9071 C CD . GLU C 2 295 ? 75.619 31.751 -6.673 1.00 41.92 ? 327 GLU C CD 1 ATOM 9072 O OE1 . GLU C 2 295 ? 75.117 32.838 -7.041 1.00 46.11 ? 327 GLU C OE1 1 ATOM 9073 O OE2 . GLU C 2 295 ? 75.177 30.668 -7.081 1.00 44.70 -1 327 GLU C OE2 1 ATOM 9074 N N . LYS C 2 296 ? 79.844 28.818 -3.559 1.00 41.28 ? 328 LYS C N 1 ATOM 9075 C CA . LYS C 2 296 ? 80.268 27.483 -3.117 1.00 41.84 ? 328 LYS C CA 1 ATOM 9076 C C . LYS C 2 296 ? 79.182 26.444 -3.350 1.00 40.07 ? 328 LYS C C 1 ATOM 9077 O O . LYS C 2 296 ? 79.417 25.363 -3.868 1.00 38.58 ? 328 LYS C O 1 ATOM 9078 C CB . LYS C 2 296 ? 80.578 27.555 -1.625 1.00 47.61 ? 328 LYS C CB 1 ATOM 9079 C CG . LYS C 2 296 ? 81.107 26.268 -1.019 1.00 51.58 ? 328 LYS C CG 1 ATOM 9080 C CD . LYS C 2 296 ? 82.191 26.557 0.011 1.00 55.47 ? 328 LYS C CD 1 ATOM 9081 C CE . LYS C 2 296 ? 82.826 25.278 0.537 1.00 58.40 ? 328 LYS C CE 1 ATOM 9082 N NZ . LYS C 2 296 ? 83.515 24.483 -0.526 1.00 58.41 1 328 LYS C NZ 1 ATOM 9083 N N . GLN C 2 297 ? 77.976 26.832 -2.972 1.00 41.36 ? 329 GLN C N 1 ATOM 9084 C CA . GLN C 2 297 ? 76.842 25.959 -2.892 1.00 40.77 ? 329 GLN C CA 1 ATOM 9085 C C . GLN C 2 297 ? 75.976 26.033 -4.128 1.00 40.23 ? 329 GLN C C 1 ATOM 9086 O O . GLN C 2 297 ? 75.949 27.034 -4.852 1.00 36.67 ? 329 GLN C O 1 ATOM 9087 C CB . GLN C 2 297 ? 76.005 26.374 -1.682 1.00 43.75 ? 329 GLN C CB 1 ATOM 9088 C CG . GLN C 2 297 ? 76.689 26.044 -0.372 1.00 46.76 ? 329 GLN C CG 1 ATOM 9089 C CD . GLN C 2 297 ? 77.082 24.575 -0.332 1.00 51.93 ? 329 GLN C CD 1 ATOM 9090 O OE1 . GLN C 2 297 ? 78.262 24.220 -0.257 1.00 54.51 ? 329 GLN C OE1 1 ATOM 9091 N NE2 . GLN C 2 297 ? 76.084 23.705 -0.425 1.00 56.60 ? 329 GLN C NE2 1 ATOM 9092 N N . THR C 2 298 ? 75.264 24.937 -4.350 1.00 40.17 ? 330 THR C N 1 ATOM 9093 C CA . THR C 2 298 ? 74.187 24.869 -5.325 1.00 36.89 ? 330 THR C CA 1 ATOM 9094 C C . THR C 2 298 ? 73.213 23.783 -4.816 1.00 35.25 ? 330 THR C C 1 ATOM 9095 O O . THR C 2 298 ? 73.355 23.296 -3.693 1.00 34.54 ? 330 THR C O 1 ATOM 9096 C CB . THR C 2 298 ? 74.738 24.644 -6.779 1.00 34.20 ? 330 THR C CB 1 ATOM 9097 O OG1 . THR C 2 298 ? 73.689 24.794 -7.747 1.00 32.98 ? 330 THR C OG1 1 ATOM 9098 C CG2 . THR C 2 298 ? 75.370 23.301 -6.933 1.00 32.73 ? 330 THR C CG2 1 ATOM 9099 N N . ASN C 2 299 ? 72.213 23.452 -5.622 1.00 35.01 ? 331 ASN C N 1 ATOM 9100 C CA . ASN C 2 299 ? 71.343 22.302 -5.377 1.00 35.27 ? 331 ASN C CA 1 ATOM 9101 C C . ASN C 2 299 ? 71.682 21.164 -6.343 1.00 37.09 ? 331 ASN C C 1 ATOM 9102 O O . ASN C 2 299 ? 72.129 21.423 -7.465 1.00 38.87 ? 331 ASN C O 1 ATOM 9103 C CB . ASN C 2 299 ? 69.907 22.673 -5.672 1.00 35.60 ? 331 ASN C CB 1 ATOM 9104 C CG . ASN C 2 299 ? 69.713 23.018 -7.144 1.00 34.29 ? 331 ASN C CG 1 ATOM 9105 O OD1 . ASN C 2 299 ? 70.335 23.978 -7.627 1.00 34.79 ? 331 ASN C OD1 1 ATOM 9106 N ND2 . ASN C 2 299 ? 68.922 22.212 -7.876 1.00 30.24 ? 331 ASN C ND2 1 ATOM 9107 N N . ASN C 2 300 ? 71.462 19.917 -5.907 1.00 37.83 ? 332 ASN C N 1 ATOM 9108 C CA . ASN C 2 300 ? 71.362 18.742 -6.809 1.00 37.27 ? 332 ASN C CA 1 ATOM 9109 C C . ASN C 2 300 ? 70.035 18.711 -7.543 1.00 38.13 ? 332 ASN C C 1 ATOM 9110 O O . ASN C 2 300 ? 69.029 19.229 -7.048 1.00 37.24 ? 332 ASN C O 1 ATOM 9111 C CB . ASN C 2 300 ? 71.444 17.402 -6.062 1.00 34.98 ? 332 ASN C CB 1 ATOM 9112 C CG . ASN C 2 300 ? 72.858 16.995 -5.710 1.00 33.72 ? 332 ASN C CG 1 ATOM 9113 O OD1 . ASN C 2 300 ? 73.124 16.646 -4.570 1.00 32.99 ? 332 ASN C OD1 1 ATOM 9114 N ND2 . ASN C 2 300 ? 73.764 17.028 -6.675 1.00 33.69 ? 332 ASN C ND2 1 ATOM 9115 N N . PRO C 2 301 ? 70.017 18.075 -8.723 1.00 38.30 ? 333 PRO C N 1 ATOM 9116 C CA . PRO C 2 301 ? 68.723 17.990 -9.374 1.00 36.98 ? 333 PRO C CA 1 ATOM 9117 C C . PRO C 2 301 ? 67.703 17.278 -8.488 1.00 33.40 ? 333 PRO C C 1 ATOM 9118 O O . PRO C 2 301 ? 68.053 16.397 -7.713 1.00 29.74 ? 333 PRO C O 1 ATOM 9119 C CB . PRO C 2 301 ? 69.045 17.249 -10.681 1.00 39.15 ? 333 PRO C CB 1 ATOM 9120 C CG . PRO C 2 301 ? 70.451 17.674 -10.988 1.00 38.71 ? 333 PRO C CG 1 ATOM 9121 C CD . PRO C 2 301 ? 71.123 17.740 -9.642 1.00 37.88 ? 333 PRO C CD 1 ATOM 9122 N N . GLY C 2 302 ? 66.455 17.696 -8.608 1.00 33.62 ? 334 GLY C N 1 ATOM 9123 C CA . GLY C 2 302 ? 65.421 17.304 -7.675 1.00 36.37 ? 334 GLY C CA 1 ATOM 9124 C C . GLY C 2 302 ? 63.983 17.407 -8.197 1.00 38.63 ? 334 GLY C C 1 ATOM 9125 O O . GLY C 2 302 ? 63.592 18.357 -8.902 1.00 36.19 ? 334 GLY C O 1 ATOM 9126 N N . ILE C 2 303 ? 63.196 16.431 -7.752 1.00 40.32 ? 335 ILE C N 1 ATOM 9127 C CA . ILE C 2 303 ? 61.857 16.118 -8.219 1.00 39.77 ? 335 ILE C CA 1 ATOM 9128 C C . ILE C 2 303 ? 61.074 15.781 -6.972 1.00 39.56 ? 335 ILE C C 1 ATOM 9129 O O . ILE C 2 303 ? 61.599 15.067 -6.106 1.00 39.05 ? 335 ILE C O 1 ATOM 9130 C CB . ILE C 2 303 ? 61.939 14.844 -9.076 1.00 41.41 ? 335 ILE C CB 1 ATOM 9131 C CG1 . ILE C 2 303 ? 62.463 15.197 -10.453 1.00 44.75 ? 335 ILE C CG1 1 ATOM 9132 C CG2 . ILE C 2 303 ? 60.614 14.106 -9.139 1.00 41.64 ? 335 ILE C CG2 1 ATOM 9133 C CD1 . ILE C 2 303 ? 61.766 16.388 -11.090 1.00 47.74 ? 335 ILE C CD1 1 ATOM 9134 N N . ARG C 2 304 ? 59.842 16.269 -6.848 1.00 37.04 ? 336 ARG C N 1 ATOM 9135 C CA . ARG C 2 304 ? 59.071 15.963 -5.637 1.00 36.48 ? 336 ARG C CA 1 ATOM 9136 C C . ARG C 2 304 ? 57.627 15.580 -5.945 1.00 38.44 ? 336 ARG C C 1 ATOM 9137 O O . ARG C 2 304 ? 57.114 15.838 -7.030 1.00 40.78 ? 336 ARG C O 1 ATOM 9138 C CB . ARG C 2 304 ? 59.174 17.085 -4.541 1.00 33.77 ? 336 ARG C CB 1 ATOM 9139 C CG . ARG C 2 304 ? 58.415 18.378 -4.833 1.00 31.55 ? 336 ARG C CG 1 ATOM 9140 C CD . ARG C 2 304 ? 58.233 19.288 -3.636 1.00 28.35 ? 336 ARG C CD 1 ATOM 9141 N NE . ARG C 2 304 ? 59.487 19.635 -2.987 1.00 26.39 ? 336 ARG C NE 1 ATOM 9142 C CZ . ARG C 2 304 ? 59.686 20.708 -2.221 1.00 25.15 ? 336 ARG C CZ 1 ATOM 9143 N NH1 . ARG C 2 304 ? 58.720 21.600 -2.020 1.00 25.43 1 336 ARG C NH1 1 ATOM 9144 N NH2 . ARG C 2 304 ? 60.882 20.908 -1.672 1.00 23.87 ? 336 ARG C NH2 1 ATOM 9145 N N . LEU C 2 305 ? 57.007 14.966 -4.937 1.00 39.27 ? 337 LEU C N 1 ATOM 9146 C CA . LEU C 2 305 ? 55.743 14.299 -5.017 1.00 37.45 ? 337 LEU C CA 1 ATOM 9147 C C . LEU C 2 305 ? 55.002 14.579 -3.721 1.00 38.75 ? 337 LEU C C 1 ATOM 9148 O O . LEU C 2 305 ? 55.392 14.078 -2.640 1.00 38.06 ? 337 LEU C O 1 ATOM 9149 C CB . LEU C 2 305 ? 56.020 12.813 -5.129 1.00 39.88 ? 337 LEU C CB 1 ATOM 9150 C CG . LEU C 2 305 ? 54.852 11.834 -5.110 1.00 43.84 ? 337 LEU C CG 1 ATOM 9151 C CD1 . LEU C 2 305 ? 54.016 11.988 -6.375 1.00 46.43 ? 337 LEU C CD1 1 ATOM 9152 C CD2 . LEU C 2 305 ? 55.354 10.405 -4.970 1.00 45.09 ? 337 LEU C CD2 1 ATOM 9153 N N . PHE C 2 306 ? 53.952 15.398 -3.827 1.00 39.52 ? 338 PHE C N 1 ATOM 9154 C CA . PHE C 2 306 ? 53.020 15.660 -2.710 1.00 37.69 ? 338 PHE C CA 1 ATOM 9155 C C . PHE C 2 306 ? 51.943 14.597 -2.549 1.00 42.06 ? 338 PHE C C 1 ATOM 9156 O O . PHE C 2 306 ? 51.528 13.958 -3.511 1.00 47.05 ? 338 PHE C O 1 ATOM 9157 C CB . PHE C 2 306 ? 52.325 16.980 -2.931 1.00 33.85 ? 338 PHE C CB 1 ATOM 9158 C CG . PHE C 2 306 ? 53.178 18.145 -2.596 1.00 31.93 ? 338 PHE C CG 1 ATOM 9159 C CD1 . PHE C 2 306 ? 53.379 18.497 -1.288 1.00 30.39 ? 338 PHE C CD1 1 ATOM 9160 C CD2 . PHE C 2 306 ? 53.802 18.872 -3.580 1.00 29.83 ? 338 PHE C CD2 1 ATOM 9161 C CE1 . PHE C 2 306 ? 54.149 19.586 -0.974 1.00 29.52 ? 338 PHE C CE1 1 ATOM 9162 C CE2 . PHE C 2 306 ? 54.579 19.961 -3.269 1.00 27.78 ? 338 PHE C CE2 1 ATOM 9163 C CZ . PHE C 2 306 ? 54.750 20.318 -1.972 1.00 27.94 ? 338 PHE C CZ 1 ATOM 9164 N N . GLN C 2 307 ? 51.477 14.418 -1.323 1.00 45.72 ? 339 GLN C N 1 ATOM 9165 C CA . GLN C 2 307 ? 50.396 13.481 -1.040 1.00 44.29 ? 339 GLN C CA 1 ATOM 9166 C C . GLN C 2 307 ? 49.228 14.221 -0.466 1.00 47.10 ? 339 GLN C C 1 ATOM 9167 O O . GLN C 2 307 ? 49.398 15.185 0.289 1.00 52.30 ? 339 GLN C O 1 ATOM 9168 C CB . GLN C 2 307 ? 50.839 12.446 -0.029 1.00 41.83 ? 339 GLN C CB 1 ATOM 9169 C CG . GLN C 2 307 ? 51.895 11.514 -0.566 1.00 41.23 ? 339 GLN C CG 1 ATOM 9170 C CD . GLN C 2 307 ? 52.120 10.355 0.357 1.00 41.29 ? 339 GLN C CD 1 ATOM 9171 O OE1 . GLN C 2 307 ? 51.782 10.420 1.548 1.00 44.19 ? 339 GLN C OE1 1 ATOM 9172 N NE2 . GLN C 2 307 ? 52.684 9.282 -0.174 1.00 40.66 ? 339 GLN C NE2 1 ATOM 9173 N N . TYR C 2 308 ? 48.032 13.756 -0.779 1.00 47.71 ? 340 TYR C N 1 ATOM 9174 C CA . TYR C 2 308 ? 46.873 14.349 -0.167 1.00 46.85 ? 340 TYR C CA 1 ATOM 9175 C C . TYR C 2 308 ? 45.750 13.389 0.171 1.00 47.25 ? 340 TYR C C 1 ATOM 9176 O O . TYR C 2 308 ? 45.772 12.191 -0.164 1.00 42.85 ? 340 TYR C O 1 ATOM 9177 C CB . TYR C 2 308 ? 46.360 15.478 -1.040 1.00 48.68 ? 340 TYR C CB 1 ATOM 9178 C CG . TYR C 2 308 ? 45.931 15.084 -2.445 1.00 50.00 ? 340 TYR C CG 1 ATOM 9179 C CD1 . TYR C 2 308 ? 46.872 14.894 -3.447 1.00 50.87 ? 340 TYR C CD1 1 ATOM 9180 C CD2 . TYR C 2 308 ? 44.572 14.970 -2.786 1.00 48.72 ? 340 TYR C CD2 1 ATOM 9181 C CE1 . TYR C 2 308 ? 46.482 14.581 -4.747 1.00 52.06 ? 340 TYR C CE1 1 ATOM 9182 C CE2 . TYR C 2 308 ? 44.175 14.660 -4.079 1.00 47.49 ? 340 TYR C CE2 1 ATOM 9183 C CZ . TYR C 2 308 ? 45.134 14.467 -5.062 1.00 49.43 ? 340 TYR C CZ 1 ATOM 9184 O OH . TYR C 2 308 ? 44.780 14.160 -6.365 1.00 47.10 ? 340 TYR C OH 1 ATOM 9185 N N . ASP C 2 309 ? 44.801 13.967 0.904 1.00 49.93 ? 341 ASP C N 1 ATOM 9186 C CA . ASP C 2 309 ? 43.543 13.358 1.283 1.00 49.39 ? 341 ASP C CA 1 ATOM 9187 C C . ASP C 2 309 ? 42.463 13.847 0.318 1.00 44.93 ? 341 ASP C C 1 ATOM 9188 O O . ASP C 2 309 ? 42.088 15.034 0.337 1.00 44.03 ? 341 ASP C O 1 ATOM 9189 C CB . ASP C 2 309 ? 43.194 13.792 2.703 1.00 53.83 ? 341 ASP C CB 1 ATOM 9190 C CG . ASP C 2 309 ? 42.107 12.958 3.312 1.00 58.85 ? 341 ASP C CG 1 ATOM 9191 O OD1 . ASP C 2 309 ? 41.733 11.937 2.677 1.00 64.89 ? 341 ASP C OD1 1 ATOM 9192 O OD2 . ASP C 2 309 ? 41.648 13.320 4.429 1.00 60.67 -1 341 ASP C OD2 1 ATOM 9193 N N . PRO C 2 310 ? 41.944 12.942 -0.517 1.00 39.85 ? 342 PRO C N 1 ATOM 9194 C CA . PRO C 2 310 ? 41.055 13.344 -1.595 1.00 40.13 ? 342 PRO C CA 1 ATOM 9195 C C . PRO C 2 310 ? 39.754 14.025 -1.178 1.00 40.73 ? 342 PRO C C 1 ATOM 9196 O O . PRO C 2 310 ? 38.989 14.438 -2.049 1.00 45.32 ? 342 PRO C O 1 ATOM 9197 C CB . PRO C 2 310 ? 40.757 12.030 -2.297 1.00 40.04 ? 342 PRO C CB 1 ATOM 9198 C CG . PRO C 2 310 ? 41.943 11.184 -2.020 1.00 39.53 ? 342 PRO C CG 1 ATOM 9199 C CD . PRO C 2 310 ? 42.309 11.524 -0.615 1.00 39.86 ? 342 PRO C CD 1 ATOM 9200 N N . ARG C 2 311 ? 39.518 14.158 0.121 1.00 40.48 ? 343 ARG C N 1 ATOM 9201 C CA . ARG C 2 311 ? 38.282 14.719 0.647 1.00 41.19 ? 343 ARG C CA 1 ATOM 9202 C C . ARG C 2 311 ? 38.374 16.218 0.846 1.00 38.76 ? 343 ARG C C 1 ATOM 9203 O O . ARG C 2 311 ? 37.635 16.971 0.234 1.00 37.61 ? 343 ARG C O 1 ATOM 9204 C CB . ARG C 2 311 ? 37.927 14.016 1.966 1.00 44.79 ? 343 ARG C CB 1 ATOM 9205 C CG . ARG C 2 311 ? 37.719 12.509 1.783 1.00 49.38 ? 343 ARG C CG 1 ATOM 9206 C CD . ARG C 2 311 ? 37.514 11.763 3.091 1.00 52.08 ? 343 ARG C CD 1 ATOM 9207 N NE . ARG C 2 311 ? 38.764 11.297 3.689 1.00 52.78 ? 343 ARG C NE 1 ATOM 9208 C CZ . ARG C 2 311 ? 38.949 11.100 4.993 1.00 54.68 ? 343 ARG C CZ 1 ATOM 9209 N NH1 . ARG C 2 311 ? 37.973 11.330 5.859 1.00 54.96 1 343 ARG C NH1 1 ATOM 9210 N NH2 . ARG C 2 311 ? 40.128 10.679 5.441 1.00 57.90 ? 343 ARG C NH2 1 ATOM 9211 N N . ASP C 2 312 ? 39.285 16.643 1.707 1.00 39.52 ? 344 ASP C N 1 ATOM 9212 C CA . ASP C 2 312 ? 39.501 18.074 1.981 1.00 41.10 ? 344 ASP C CA 1 ATOM 9213 C C . ASP C 2 312 ? 40.752 18.620 1.257 1.00 41.05 ? 344 ASP C C 1 ATOM 9214 O O . ASP C 2 312 ? 41.013 19.828 1.325 1.00 38.15 ? 344 ASP C O 1 ATOM 9215 C CB . ASP C 2 312 ? 39.564 18.380 3.510 1.00 41.14 ? 344 ASP C CB 1 ATOM 9216 C CG . ASP C 2 312 ? 40.378 17.320 4.342 1.00 40.73 ? 344 ASP C CG 1 ATOM 9217 O OD1 . ASP C 2 312 ? 41.117 16.492 3.755 1.00 41.82 ? 344 ASP C OD1 1 ATOM 9218 O OD2 . ASP C 2 312 ? 40.268 17.305 5.593 1.00 36.04 -1 344 ASP C OD2 1 ATOM 9219 N N . TYR C 2 313 ? 41.491 17.730 0.569 1.00 40.42 ? 345 TYR C N 1 ATOM 9220 C CA . TYR C 2 313 ? 42.748 18.063 -0.155 1.00 42.51 ? 345 TYR C CA 1 ATOM 9221 C C . TYR C 2 313 ? 43.865 18.548 0.787 1.00 48.15 ? 345 TYR C C 1 ATOM 9222 O O . TYR C 2 313 ? 44.789 19.266 0.375 1.00 48.24 ? 345 TYR C O 1 ATOM 9223 C CB . TYR C 2 313 ? 42.493 19.030 -1.347 1.00 40.58 ? 345 TYR C CB 1 ATOM 9224 C CG . TYR C 2 313 ? 41.522 18.399 -2.284 1.00 37.13 ? 345 TYR C CG 1 ATOM 9225 C CD1 . TYR C 2 313 ? 41.928 17.373 -3.118 1.00 36.30 ? 345 TYR C CD1 1 ATOM 9226 C CD2 . TYR C 2 313 ? 40.184 18.729 -2.244 1.00 35.50 ? 345 TYR C CD2 1 ATOM 9227 C CE1 . TYR C 2 313 ? 41.034 16.724 -3.926 1.00 36.23 ? 345 TYR C CE1 1 ATOM 9228 C CE2 . TYR C 2 313 ? 39.275 18.080 -3.037 1.00 35.40 ? 345 TYR C CE2 1 ATOM 9229 C CZ . TYR C 2 313 ? 39.711 17.078 -3.874 1.00 36.61 ? 345 TYR C CZ 1 ATOM 9230 O OH . TYR C 2 313 ? 38.824 16.422 -4.674 1.00 38.53 ? 345 TYR C OH 1 ATOM 9231 N N . LYS C 2 314 ? 43.761 18.118 2.048 1.00 51.50 ? 346 LYS C N 1 ATOM 9232 C CA . LYS C 2 314 ? 44.775 18.327 3.078 1.00 54.88 ? 346 LYS C CA 1 ATOM 9233 C C . LYS C 2 314 ? 46.078 17.593 2.680 1.00 50.67 ? 346 LYS C C 1 ATOM 9234 O O . LYS C 2 314 ? 46.041 16.527 2.057 1.00 48.17 ? 346 LYS C O 1 ATOM 9235 C CB . LYS C 2 314 ? 44.196 17.849 4.433 1.00 64.69 ? 346 LYS C CB 1 ATOM 9236 C CG . LYS C 2 314 ? 45.126 17.799 5.650 1.00 73.78 ? 346 LYS C CG 1 ATOM 9237 C CD . LYS C 2 314 ? 44.326 17.682 6.962 1.00 76.99 ? 346 LYS C CD 1 ATOM 9238 C CE . LYS C 2 314 ? 45.036 16.823 8.008 1.00 81.01 ? 346 LYS C CE 1 ATOM 9239 N NZ . LYS C 2 314 ? 44.883 15.360 7.724 1.00 83.37 1 346 LYS C NZ 1 ATOM 9240 N N . LEU C 2 315 ? 47.223 18.196 3.012 1.00 47.32 ? 347 LEU C N 1 ATOM 9241 C CA . LEU C 2 315 ? 48.536 17.685 2.591 1.00 43.08 ? 347 LEU C CA 1 ATOM 9242 C C . LEU C 2 315 ? 49.137 16.756 3.615 1.00 39.98 ? 347 LEU C C 1 ATOM 9243 O O . LEU C 2 315 ? 49.472 17.179 4.706 1.00 38.34 ? 347 LEU C O 1 ATOM 9244 C CB . LEU C 2 315 ? 49.495 18.842 2.322 1.00 40.86 ? 347 LEU C CB 1 ATOM 9245 C CG . LEU C 2 315 ? 49.210 19.518 0.986 1.00 38.60 ? 347 LEU C CG 1 ATOM 9246 C CD1 . LEU C 2 315 ? 50.113 20.734 0.779 1.00 36.89 ? 347 LEU C CD1 1 ATOM 9247 C CD2 . LEU C 2 315 ? 49.340 18.492 -0.146 1.00 38.05 ? 347 LEU C CD2 1 ATOM 9248 N N . LEU C 2 316 ? 49.279 15.489 3.249 1.00 39.46 ? 348 LEU C N 1 ATOM 9249 C CA . LEU C 2 316 ? 49.638 14.454 4.219 1.00 41.34 ? 348 LEU C CA 1 ATOM 9250 C C . LEU C 2 316 ? 51.149 14.315 4.310 1.00 40.18 ? 348 LEU C C 1 ATOM 9251 O O . LEU C 2 316 ? 51.725 14.198 5.410 1.00 37.09 ? 348 LEU C O 1 ATOM 9252 C CB . LEU C 2 316 ? 48.963 13.114 3.864 1.00 41.51 ? 348 LEU C CB 1 ATOM 9253 C CG . LEU C 2 316 ? 47.420 13.205 3.895 1.00 41.78 ? 348 LEU C CG 1 ATOM 9254 C CD1 . LEU C 2 316 ? 46.800 11.879 3.493 1.00 41.96 ? 348 LEU C CD1 1 ATOM 9255 C CD2 . LEU C 2 316 ? 46.870 13.673 5.240 1.00 41.32 ? 348 LEU C CD2 1 ATOM 9256 N N . ASP C 2 317 ? 51.794 14.364 3.154 1.00 37.82 ? 349 ASP C N 1 ATOM 9257 C CA . ASP C 2 317 ? 53.227 14.310 3.140 1.00 34.52 ? 349 ASP C CA 1 ATOM 9258 C C . ASP C 2 317 ? 53.769 14.831 1.817 1.00 33.12 ? 349 ASP C C 1 ATOM 9259 O O . ASP C 2 317 ? 53.028 15.196 0.908 1.00 31.57 ? 349 ASP C O 1 ATOM 9260 C CB . ASP C 2 317 ? 53.674 12.868 3.407 1.00 33.40 ? 349 ASP C CB 1 ATOM 9261 C CG . ASP C 2 317 ? 54.980 12.774 4.212 1.00 32.19 ? 349 ASP C CG 1 ATOM 9262 O OD1 . ASP C 2 317 ? 55.753 13.742 4.305 1.00 30.14 ? 349 ASP C OD1 1 ATOM 9263 O OD2 . ASP C 2 317 ? 55.248 11.687 4.738 1.00 31.83 -1 349 ASP C OD2 1 ATOM 9264 N N . MET C 2 318 ? 55.087 14.904 1.764 1.00 33.94 ? 350 MET C N 1 ATOM 9265 C CA . MET C 2 318 ? 55.821 15.273 0.583 1.00 33.59 ? 350 MET C CA 1 ATOM 9266 C C . MET C 2 318 ? 57.114 14.457 0.580 1.00 32.85 ? 350 MET C C 1 ATOM 9267 O O . MET C 2 318 ? 57.867 14.435 1.572 1.00 30.77 ? 350 MET C O 1 ATOM 9268 C CB . MET C 2 318 ? 56.103 16.779 0.617 1.00 34.19 ? 350 MET C CB 1 ATOM 9269 C CG . MET C 2 318 ? 56.826 17.288 -0.607 1.00 34.55 ? 350 MET C CG 1 ATOM 9270 S SD . MET C 2 318 ? 58.537 17.580 -0.216 1.00 34.11 ? 350 MET C SD 1 ATOM 9271 C CE . MET C 2 318 ? 58.306 19.276 0.338 1.00 33.78 ? 350 MET C CE 1 ATOM 9272 N N . LEU C 2 319 ? 57.340 13.758 -0.527 1.00 33.02 ? 351 LEU C N 1 ATOM 9273 C CA . LEU C 2 319 ? 58.530 12.934 -0.697 1.00 33.85 ? 351 LEU C CA 1 ATOM 9274 C C . LEU C 2 319 ? 59.463 13.584 -1.721 1.00 35.60 ? 351 LEU C C 1 ATOM 9275 O O . LEU C 2 319 ? 59.079 13.723 -2.884 1.00 35.11 ? 351 LEU C O 1 ATOM 9276 C CB . LEU C 2 319 ? 58.152 11.561 -1.228 1.00 33.78 ? 351 LEU C CB 1 ATOM 9277 C CG . LEU C 2 319 ? 57.087 10.783 -0.482 1.00 33.06 ? 351 LEU C CG 1 ATOM 9278 C CD1 . LEU C 2 319 ? 55.676 11.215 -0.874 1.00 31.55 ? 351 LEU C CD1 1 ATOM 9279 C CD2 . LEU C 2 319 ? 57.319 9.327 -0.828 1.00 34.04 ? 351 LEU C CD2 1 ATOM 9280 N N . GLN C 2 320 ? 60.690 13.925 -1.293 1.00 36.54 ? 352 GLN C N 1 ATOM 9281 C CA . GLN C 2 320 ? 61.698 14.610 -2.117 1.00 36.11 ? 352 GLN C CA 1 ATOM 9282 C C . GLN C 2 320 ? 62.717 13.632 -2.761 1.00 34.07 ? 352 GLN C C 1 ATOM 9283 O O . GLN C 2 320 ? 63.549 13.068 -2.048 1.00 35.57 ? 352 GLN C O 1 ATOM 9284 C CB . GLN C 2 320 ? 62.434 15.639 -1.240 1.00 37.56 ? 352 GLN C CB 1 ATOM 9285 C CG . GLN C 2 320 ? 63.429 16.532 -1.980 1.00 39.77 ? 352 GLN C CG 1 ATOM 9286 C CD . GLN C 2 320 ? 62.785 17.598 -2.865 1.00 41.16 ? 352 GLN C CD 1 ATOM 9287 O OE1 . GLN C 2 320 ? 61.817 18.240 -2.463 1.00 44.53 ? 352 GLN C OE1 1 ATOM 9288 N NE2 . GLN C 2 320 ? 63.346 17.816 -4.060 1.00 42.22 ? 352 GLN C NE2 1 ATOM 9289 N N . TYR C 2 321 ? 62.654 13.451 -4.094 1.00 31.49 ? 353 TYR C N 1 ATOM 9290 C CA . TYR C 2 321 ? 63.631 12.635 -4.855 1.00 28.30 ? 353 TYR C CA 1 ATOM 9291 C C . TYR C 2 321 ? 64.755 13.492 -5.381 1.00 26.89 ? 353 TYR C C 1 ATOM 9292 O O . TYR C 2 321 ? 64.596 14.716 -5.509 1.00 25.48 ? 353 TYR C O 1 ATOM 9293 C CB . TYR C 2 321 ? 62.959 11.899 -6.014 1.00 26.78 ? 353 TYR C CB 1 ATOM 9294 C CG . TYR C 2 321 ? 61.895 10.961 -5.533 1.00 27.12 ? 353 TYR C CG 1 ATOM 9295 C CD1 . TYR C 2 321 ? 62.207 9.677 -5.051 1.00 27.12 ? 353 TYR C CD1 1 ATOM 9296 C CD2 . TYR C 2 321 ? 60.576 11.368 -5.493 1.00 27.81 ? 353 TYR C CD2 1 ATOM 9297 C CE1 . TYR C 2 321 ? 61.211 8.829 -4.572 1.00 26.43 ? 353 TYR C CE1 1 ATOM 9298 C CE2 . TYR C 2 321 ? 59.582 10.536 -5.008 1.00 27.78 ? 353 TYR C CE2 1 ATOM 9299 C CZ . TYR C 2 321 ? 59.897 9.278 -4.561 1.00 26.87 ? 353 TYR C CZ 1 ATOM 9300 O OH . TYR C 2 321 ? 58.857 8.518 -4.132 1.00 26.47 ? 353 TYR C OH 1 ATOM 9301 N N . TYR C 2 322 ? 65.892 12.864 -5.684 1.00 26.77 ? 354 TYR C N 1 ATOM 9302 C CA . TYR C 2 322 ? 67.043 13.622 -6.209 1.00 27.06 ? 354 TYR C CA 1 ATOM 9303 C C . TYR C 2 322 ? 68.028 12.862 -7.049 1.00 25.41 ? 354 TYR C C 1 ATOM 9304 O O . TYR C 2 322 ? 67.879 11.682 -7.233 1.00 22.92 ? 354 TYR C O 1 ATOM 9305 C CB . TYR C 2 322 ? 67.769 14.344 -5.076 1.00 28.50 ? 354 TYR C CB 1 ATOM 9306 C CG . TYR C 2 322 ? 68.787 13.576 -4.246 1.00 28.44 ? 354 TYR C CG 1 ATOM 9307 C CD1 . TYR C 2 322 ? 68.404 12.558 -3.351 1.00 28.11 ? 354 TYR C CD1 1 ATOM 9308 C CD2 . TYR C 2 322 ? 70.137 13.947 -4.280 1.00 27.62 ? 354 TYR C CD2 1 ATOM 9309 C CE1 . TYR C 2 322 ? 69.370 11.920 -2.569 1.00 27.30 ? 354 TYR C CE1 1 ATOM 9310 C CE2 . TYR C 2 322 ? 71.084 13.309 -3.506 1.00 26.28 ? 354 TYR C CE2 1 ATOM 9311 C CZ . TYR C 2 322 ? 70.696 12.317 -2.665 1.00 25.77 ? 354 TYR C CZ 1 ATOM 9312 O OH . TYR C 2 322 ? 71.670 11.747 -1.956 1.00 25.34 ? 354 TYR C OH 1 ATOM 9313 N N . LEU C 2 323 ? 69.065 13.550 -7.491 1.00 26.99 ? 355 LEU C N 1 ATOM 9314 C CA . LEU C 2 323 ? 70.133 12.962 -8.274 1.00 30.04 ? 355 LEU C CA 1 ATOM 9315 C C . LEU C 2 323 ? 71.522 13.408 -7.794 1.00 34.16 ? 355 LEU C C 1 ATOM 9316 O O . LEU C 2 323 ? 71.793 14.568 -7.844 1.00 35.05 ? 355 LEU C O 1 ATOM 9317 C CB . LEU C 2 323 ? 69.966 13.398 -9.707 1.00 28.46 ? 355 LEU C CB 1 ATOM 9318 C CG . LEU C 2 323 ? 71.021 13.050 -10.711 1.00 27.80 ? 355 LEU C CG 1 ATOM 9319 C CD1 . LEU C 2 323 ? 70.982 11.600 -10.987 1.00 27.64 ? 355 LEU C CD1 1 ATOM 9320 C CD2 . LEU C 2 323 ? 70.773 13.790 -11.984 1.00 28.21 ? 355 LEU C CD2 1 ATOM 9321 N N . ASN C 2 324 ? 72.396 12.505 -7.333 1.00 37.10 ? 356 ASN C N 1 ATOM 9322 C CA . ASN C 2 324 ? 73.738 12.897 -6.917 1.00 39.30 ? 356 ASN C CA 1 ATOM 9323 C C . ASN C 2 324 ? 74.434 13.162 -8.204 1.00 40.67 ? 356 ASN C C 1 ATOM 9324 O O . ASN C 2 324 ? 74.723 12.255 -8.931 1.00 43.40 ? 356 ASN C O 1 ATOM 9325 C CB . ASN C 2 324 ? 74.458 11.799 -6.177 1.00 41.18 ? 356 ASN C CB 1 ATOM 9326 C CG . ASN C 2 324 ? 75.756 12.262 -5.615 1.00 45.87 ? 356 ASN C CG 1 ATOM 9327 O OD1 . ASN C 2 324 ? 76.238 13.289 -6.011 1.00 45.70 ? 356 ASN C OD1 1 ATOM 9328 N ND2 . ASN C 2 324 ? 76.319 11.533 -4.670 1.00 51.11 ? 356 ASN C ND2 1 ATOM 9329 N N . LEU C 2 325 ? 74.707 14.409 -8.506 1.00 38.09 ? 357 LEU C N 1 ATOM 9330 C CA . LEU C 2 325 ? 75.190 14.782 -9.833 1.00 36.25 ? 357 LEU C CA 1 ATOM 9331 C C . LEU C 2 325 ? 76.575 14.258 -10.007 1.00 32.75 ? 357 LEU C C 1 ATOM 9332 O O . LEU C 2 325 ? 76.830 13.466 -10.890 1.00 32.06 ? 357 LEU C O 1 ATOM 9333 C CB . LEU C 2 325 ? 75.172 16.304 -10.044 1.00 39.27 ? 357 LEU C CB 1 ATOM 9334 C CG . LEU C 2 325 ? 75.519 16.820 -11.461 1.00 40.73 ? 357 LEU C CG 1 ATOM 9335 C CD1 . LEU C 2 325 ? 74.523 16.265 -12.484 1.00 40.87 ? 357 LEU C CD1 1 ATOM 9336 C CD2 . LEU C 2 325 ? 75.604 18.357 -11.535 1.00 39.65 ? 357 LEU C CD2 1 ATOM 9337 N N . THR C 2 326 ? 77.466 14.681 -9.134 1.00 30.93 ? 358 THR C N 1 ATOM 9338 C CA . THR C 2 326 ? 78.780 14.146 -9.153 1.00 31.34 ? 358 THR C CA 1 ATOM 9339 C C . THR C 2 326 ? 78.716 12.659 -9.396 1.00 33.91 ? 358 THR C C 1 ATOM 9340 O O . THR C 2 326 ? 79.379 12.201 -10.283 1.00 36.47 ? 358 THR C O 1 ATOM 9341 C CB . THR C 2 326 ? 79.554 14.471 -7.877 1.00 30.72 ? 358 THR C CB 1 ATOM 9342 O OG1 . THR C 2 326 ? 80.289 15.675 -8.096 1.00 28.99 ? 358 THR C OG1 1 ATOM 9343 C CG2 . THR C 2 326 ? 80.553 13.387 -7.543 1.00 31.52 ? 358 THR C CG2 1 ATOM 9344 N N . GLU C 2 327 ? 77.922 11.907 -8.648 1.00 39.32 ? 359 GLU C N 1 ATOM 9345 C CA . GLU C 2 327 ? 77.933 10.427 -8.781 1.00 48.98 ? 359 GLU C CA 1 ATOM 9346 C C . GLU C 2 327 ? 77.397 9.949 -10.134 1.00 50.98 ? 359 GLU C C 1 ATOM 9347 O O . GLU C 2 327 ? 77.999 9.076 -10.787 1.00 48.89 ? 359 GLU C O 1 ATOM 9348 C CB . GLU C 2 327 ? 77.155 9.717 -7.624 1.00 55.43 ? 359 GLU C CB 1 ATOM 9349 C CG . GLU C 2 327 ? 76.826 8.226 -7.863 1.00 55.74 ? 359 GLU C CG 1 ATOM 9350 C CD . GLU C 2 327 ? 76.128 7.571 -6.689 1.00 55.29 ? 359 GLU C CD 1 ATOM 9351 O OE1 . GLU C 2 327 ? 76.843 7.249 -5.727 1.00 53.52 ? 359 GLU C OE1 1 ATOM 9352 O OE2 . GLU C 2 327 ? 74.886 7.366 -6.736 1.00 57.01 -1 359 GLU C OE2 1 ATOM 9353 N N . ALA C 2 328 ? 76.249 10.498 -10.524 1.00 53.43 ? 360 ALA C N 1 ATOM 9354 C CA . ALA C 2 328 ? 75.597 10.121 -11.772 1.00 55.37 ? 360 ALA C CA 1 ATOM 9355 C C . ALA C 2 328 ? 76.567 10.260 -12.928 1.00 53.11 ? 360 ALA C C 1 ATOM 9356 O O . ALA C 2 328 ? 76.587 9.425 -13.816 1.00 53.90 ? 360 ALA C O 1 ATOM 9357 C CB . ALA C 2 328 ? 74.357 10.975 -12.016 1.00 58.50 ? 360 ALA C CB 1 ATOM 9358 N N . ASN C 2 329 ? 77.382 11.309 -12.906 1.00 52.24 ? 361 ASN C N 1 ATOM 9359 C CA . ASN C 2 329 ? 78.444 11.456 -13.899 1.00 52.72 ? 361 ASN C CA 1 ATOM 9360 C C . ASN C 2 329 ? 79.585 10.399 -13.759 1.00 55.62 ? 361 ASN C C 1 ATOM 9361 O O . ASN C 2 329 ? 79.937 9.791 -14.759 1.00 60.96 ? 361 ASN C O 1 ATOM 9362 C CB . ASN C 2 329 ? 78.924 12.915 -13.963 1.00 47.87 ? 361 ASN C CB 1 ATOM 9363 C CG . ASN C 2 329 ? 77.826 13.862 -14.463 1.00 45.36 ? 361 ASN C CG 1 ATOM 9364 O OD1 . ASN C 2 329 ? 76.934 13.466 -15.207 1.00 41.27 ? 361 ASN C OD1 1 ATOM 9365 N ND2 . ASN C 2 329 ? 77.894 15.111 -14.057 1.00 44.64 ? 361 ASN C ND2 1 ATOM 9366 N N . LEU C 2 330 ? 80.099 10.118 -12.554 1.00 56.71 ? 362 LEU C N 1 ATOM 9367 C CA . LEU C 2 330 ? 81.120 9.047 -12.370 1.00 58.33 ? 362 LEU C CA 1 ATOM 9368 C C . LEU C 2 330 ? 80.660 7.657 -12.860 1.00 61.93 ? 362 LEU C C 1 ATOM 9369 O O . LEU C 2 330 ? 81.401 6.966 -13.578 1.00 57.95 ? 362 LEU C O 1 ATOM 9370 C CB . LEU C 2 330 ? 81.566 8.899 -10.908 1.00 58.15 ? 362 LEU C CB 1 ATOM 9371 C CG . LEU C 2 330 ? 81.899 10.122 -10.045 1.00 61.65 ? 362 LEU C CG 1 ATOM 9372 C CD1 . LEU C 2 330 ? 82.718 9.690 -8.830 1.00 59.61 ? 362 LEU C CD1 1 ATOM 9373 C CD2 . LEU C 2 330 ? 82.586 11.248 -10.826 1.00 62.07 ? 362 LEU C CD2 1 ATOM 9374 N N . LYS C 2 331 ? 79.460 7.240 -12.442 1.00 65.66 ? 363 LYS C N 1 ATOM 9375 C CA . LYS C 2 331 ? 78.848 5.972 -12.915 1.00 65.39 ? 363 LYS C CA 1 ATOM 9376 C C . LYS C 2 331 ? 78.408 6.068 -14.382 1.00 60.21 ? 363 LYS C C 1 ATOM 9377 O O . LYS C 2 331 ? 78.440 5.085 -15.122 1.00 51.63 ? 363 LYS C O 1 ATOM 9378 C CB . LYS C 2 331 ? 77.640 5.568 -12.041 1.00 66.62 ? 363 LYS C CB 1 ATOM 9379 C CG . LYS C 2 331 ? 78.003 5.199 -10.599 1.00 70.23 ? 363 LYS C CG 1 ATOM 9380 C CD . LYS C 2 331 ? 76.791 4.879 -9.717 1.00 73.84 ? 363 LYS C CD 1 ATOM 9381 C CE . LYS C 2 331 ? 76.055 3.611 -10.160 1.00 77.45 ? 363 LYS C CE 1 ATOM 9382 N NZ . LYS C 2 331 ? 75.170 3.028 -9.104 1.00 79.23 1 363 LYS C NZ 1 ATOM 9383 N N . GLY C 2 332 ? 78.012 7.270 -14.787 1.00 59.53 ? 364 GLY C N 1 ATOM 9384 C CA . GLY C 2 332 ? 77.402 7.497 -16.085 1.00 57.67 ? 364 GLY C CA 1 ATOM 9385 C C . GLY C 2 332 ? 75.986 6.959 -16.124 1.00 58.05 ? 364 GLY C C 1 ATOM 9386 O O . GLY C 2 332 ? 75.532 6.535 -17.181 1.00 58.43 ? 364 GLY C O 1 ATOM 9387 N N . GLU C 2 333 ? 75.294 6.972 -14.975 1.00 60.30 ? 365 GLU C N 1 ATOM 9388 C CA . GLU C 2 333 ? 73.901 6.502 -14.872 1.00 61.27 ? 365 GLU C CA 1 ATOM 9389 C C . GLU C 2 333 ? 73.027 7.455 -14.044 1.00 59.90 ? 365 GLU C C 1 ATOM 9390 O O . GLU C 2 333 ? 73.502 8.042 -13.071 1.00 58.68 ? 365 GLU C O 1 ATOM 9391 C CB . GLU C 2 333 ? 73.853 5.103 -14.243 1.00 65.81 ? 365 GLU C CB 1 ATOM 9392 C CG . GLU C 2 333 ? 74.557 3.992 -15.027 1.00 69.78 ? 365 GLU C CG 1 ATOM 9393 C CD . GLU C 2 333 ? 73.935 3.660 -16.394 1.00 71.90 ? 365 GLU C CD 1 ATOM 9394 O OE1 . GLU C 2 333 ? 72.756 4.003 -16.662 1.00 72.42 ? 365 GLU C OE1 1 ATOM 9395 O OE2 . GLU C 2 333 ? 74.645 3.030 -17.214 1.00 70.66 -1 365 GLU C OE2 1 ATOM 9396 N N . SER C 2 334 ? 71.753 7.590 -14.435 1.00 59.30 ? 366 SER C N 1 ATOM 9397 C CA . SER C 2 334 ? 70.773 8.449 -13.734 1.00 56.86 ? 366 SER C CA 1 ATOM 9398 C C . SER C 2 334 ? 70.186 7.779 -12.497 1.00 56.40 ? 366 SER C C 1 ATOM 9399 O O . SER C 2 334 ? 69.063 7.269 -12.527 1.00 55.36 ? 366 SER C O 1 ATOM 9400 C CB . SER C 2 334 ? 69.621 8.821 -14.665 1.00 55.56 ? 366 SER C CB 1 ATOM 9401 O OG . SER C 2 334 ? 70.079 9.678 -15.676 1.00 56.77 ? 366 SER C OG 1 ATOM 9402 N N . ILE C 2 335 ? 70.933 7.826 -11.401 1.00 56.51 ? 367 ILE C N 1 ATOM 9403 C CA . ILE C 2 335 ? 70.537 7.172 -10.155 1.00 57.11 ? 367 ILE C CA 1 ATOM 9404 C C . ILE C 2 335 ? 69.573 8.073 -9.362 1.00 49.86 ? 367 ILE C C 1 ATOM 9405 O O . ILE C 2 335 ? 69.939 8.545 -8.292 1.00 52.97 ? 367 ILE C O 1 ATOM 9406 C CB . ILE C 2 335 ? 71.783 6.839 -9.260 1.00 61.13 ? 367 ILE C CB 1 ATOM 9407 C CG1 . ILE C 2 335 ? 72.948 6.263 -10.085 1.00 60.18 ? 367 ILE C CG1 1 ATOM 9408 C CG2 . ILE C 2 335 ? 71.402 5.868 -8.134 1.00 62.57 ? 367 ILE C CG2 1 ATOM 9409 C CD1 . ILE C 2 335 ? 72.564 5.058 -10.922 1.00 60.98 ? 367 ILE C CD1 1 ATOM 9410 N N . TRP C 2 336 ? 68.358 8.318 -9.863 1.00 43.46 ? 368 TRP C N 1 ATOM 9411 C CA . TRP C 2 336 ? 67.386 9.148 -9.113 1.00 41.82 ? 368 TRP C CA 1 ATOM 9412 C C . TRP C 2 336 ? 66.943 8.440 -7.821 1.00 41.53 ? 368 TRP C C 1 ATOM 9413 O O . TRP C 2 336 ? 66.162 7.494 -7.866 1.00 42.16 ? 368 TRP C O 1 ATOM 9414 C CB . TRP C 2 336 ? 66.148 9.552 -9.947 1.00 39.85 ? 368 TRP C CB 1 ATOM 9415 C CG . TRP C 2 336 ? 66.353 10.781 -10.811 1.00 37.74 ? 368 TRP C CG 1 ATOM 9416 C CD1 . TRP C 2 336 ? 66.699 10.804 -12.140 1.00 38.37 ? 368 TRP C CD1 1 ATOM 9417 C CD2 . TRP C 2 336 ? 66.223 12.152 -10.416 1.00 33.29 ? 368 TRP C CD2 1 ATOM 9418 N NE1 . TRP C 2 336 ? 66.784 12.102 -12.592 1.00 36.27 ? 368 TRP C NE1 1 ATOM 9419 C CE2 . TRP C 2 336 ? 66.510 12.946 -11.551 1.00 32.74 ? 368 TRP C CE2 1 ATOM 9420 C CE3 . TRP C 2 336 ? 65.889 12.781 -9.228 1.00 30.92 ? 368 TRP C CE3 1 ATOM 9421 C CZ2 . TRP C 2 336 ? 66.498 14.309 -11.517 1.00 29.87 ? 368 TRP C CZ2 1 ATOM 9422 C CZ3 . TRP C 2 336 ? 65.866 14.137 -9.207 1.00 30.43 ? 368 TRP C CZ3 1 ATOM 9423 C CH2 . TRP C 2 336 ? 66.173 14.890 -10.342 1.00 30.51 ? 368 TRP C CH2 1 ATOM 9424 N N . LYS C 2 337 ? 67.476 8.903 -6.685 1.00 40.98 ? 369 LYS C N 1 ATOM 9425 C CA . LYS C 2 337 ? 67.159 8.375 -5.354 1.00 37.95 ? 369 LYS C CA 1 ATOM 9426 C C . LYS C 2 337 ? 66.067 9.230 -4.698 1.00 35.73 ? 369 LYS C C 1 ATOM 9427 O O . LYS C 2 337 ? 65.664 10.275 -5.218 1.00 37.07 ? 369 LYS C O 1 ATOM 9428 C CB . LYS C 2 337 ? 68.409 8.340 -4.421 1.00 37.11 ? 369 LYS C CB 1 ATOM 9429 C CG . LYS C 2 337 ? 69.624 7.576 -4.936 1.00 37.29 ? 369 LYS C CG 1 ATOM 9430 C CD . LYS C 2 337 ? 70.869 7.840 -4.091 1.00 38.20 ? 369 LYS C CD 1 ATOM 9431 C CE . LYS C 2 337 ? 72.163 7.705 -4.905 1.00 39.20 ? 369 LYS C CE 1 ATOM 9432 N NZ . LYS C 2 337 ? 73.229 8.649 -4.447 1.00 38.62 1 369 LYS C NZ 1 ATOM 9433 N N . LEU C 2 338 ? 65.593 8.723 -3.564 1.00 33.07 ? 370 LEU C N 1 ATOM 9434 C CA . LEU C 2 338 ? 64.816 9.454 -2.579 1.00 30.29 ? 370 LEU C CA 1 ATOM 9435 C C . LEU C 2 338 ? 65.767 10.193 -1.599 1.00 29.22 ? 370 LEU C C 1 ATOM 9436 O O . LEU C 2 338 ? 66.658 9.574 -0.988 1.00 27.05 ? 370 LEU C O 1 ATOM 9437 C CB . LEU C 2 338 ? 63.948 8.450 -1.813 1.00 29.42 ? 370 LEU C CB 1 ATOM 9438 C CG . LEU C 2 338 ? 63.086 8.963 -0.657 1.00 29.19 ? 370 LEU C CG 1 ATOM 9439 C CD1 . LEU C 2 338 ? 61.874 9.669 -1.232 1.00 29.15 ? 370 LEU C CD1 1 ATOM 9440 C CD2 . LEU C 2 338 ? 62.665 7.865 0.317 1.00 27.63 ? 370 LEU C CD2 1 ATOM 9441 N N . GLU C 2 339 ? 65.576 11.504 -1.458 1.00 28.14 ? 371 GLU C N 1 ATOM 9442 C CA . GLU C 2 339 ? 66.277 12.285 -0.440 1.00 28.81 ? 371 GLU C CA 1 ATOM 9443 C C . GLU C 2 339 ? 65.742 12.061 0.995 1.00 29.50 ? 371 GLU C C 1 ATOM 9444 O O . GLU C 2 339 ? 66.524 11.835 1.938 1.00 31.54 ? 371 GLU C O 1 ATOM 9445 C CB . GLU C 2 339 ? 66.245 13.787 -0.779 1.00 28.99 ? 371 GLU C CB 1 ATOM 9446 C CG . GLU C 2 339 ? 67.409 14.584 -0.170 1.00 30.43 ? 371 GLU C CG 1 ATOM 9447 C CD . GLU C 2 339 ? 67.205 16.097 -0.222 1.00 32.01 ? 371 GLU C CD 1 ATOM 9448 O OE1 . GLU C 2 339 ? 66.055 16.528 -0.438 1.00 32.91 ? 371 GLU C OE1 1 ATOM 9449 O OE2 . GLU C 2 339 ? 68.180 16.864 -0.018 1.00 32.54 -1 371 GLU C OE2 1 ATOM 9450 N N . TYR C 2 340 ? 64.421 12.154 1.160 1.00 30.13 ? 372 TYR C N 1 ATOM 9451 C CA . TYR C 2 340 ? 63.758 12.162 2.499 1.00 29.25 ? 372 TYR C CA 1 ATOM 9452 C C . TYR C 2 340 ? 62.230 12.147 2.358 1.00 29.10 ? 372 TYR C C 1 ATOM 9453 O O . TYR C 2 340 ? 61.679 12.603 1.344 1.00 26.33 ? 372 TYR C O 1 ATOM 9454 C CB . TYR C 2 340 ? 64.169 13.396 3.359 1.00 27.69 ? 372 TYR C CB 1 ATOM 9455 C CG . TYR C 2 340 ? 63.544 14.739 2.946 1.00 26.69 ? 372 TYR C CG 1 ATOM 9456 C CD1 . TYR C 2 340 ? 62.312 15.129 3.432 1.00 26.07 ? 372 TYR C CD1 1 ATOM 9457 C CD2 . TYR C 2 340 ? 64.201 15.607 2.074 1.00 25.83 ? 372 TYR C CD2 1 ATOM 9458 C CE1 . TYR C 2 340 ? 61.749 16.327 3.072 1.00 25.49 ? 372 TYR C CE1 1 ATOM 9459 C CE2 . TYR C 2 340 ? 63.655 16.806 1.720 1.00 25.00 ? 372 TYR C CE2 1 ATOM 9460 C CZ . TYR C 2 340 ? 62.428 17.150 2.232 1.00 26.23 ? 372 TYR C CZ 1 ATOM 9461 O OH . TYR C 2 340 ? 61.850 18.338 1.895 1.00 29.54 ? 372 TYR C OH 1 ATOM 9462 N N . ILE C 2 341 ? 61.562 11.630 3.386 1.00 30.25 ? 373 ILE C N 1 ATOM 9463 C CA . ILE C 2 341 ? 60.123 11.849 3.550 1.00 32.83 ? 373 ILE C CA 1 ATOM 9464 C C . ILE C 2 341 ? 59.854 12.964 4.596 1.00 33.82 ? 373 ILE C C 1 ATOM 9465 O O . ILE C 2 341 ? 60.351 12.919 5.762 1.00 34.51 ? 373 ILE C O 1 ATOM 9466 C CB . ILE C 2 341 ? 59.398 10.554 3.938 1.00 33.55 ? 373 ILE C CB 1 ATOM 9467 C CG1 . ILE C 2 341 ? 59.694 9.463 2.917 1.00 35.07 ? 373 ILE C CG1 1 ATOM 9468 C CG2 . ILE C 2 341 ? 57.895 10.797 4.016 1.00 33.41 ? 373 ILE C CG2 1 ATOM 9469 C CD1 . ILE C 2 341 ? 59.347 8.096 3.441 1.00 36.68 ? 373 ILE C CD1 1 ATOM 9470 N N . LEU C 2 342 ? 59.080 13.982 4.200 1.00 31.76 ? 374 LEU C N 1 ATOM 9471 C CA . LEU C 2 342 ? 59.022 15.174 5.043 1.00 29.13 ? 374 LEU C CA 1 ATOM 9472 C C . LEU C 2 342 ? 58.478 14.875 6.485 1.00 28.57 ? 374 LEU C C 1 ATOM 9473 O O . LEU C 2 342 ? 58.968 15.434 7.472 1.00 30.50 ? 374 LEU C O 1 ATOM 9474 C CB . LEU C 2 342 ? 58.329 16.347 4.330 1.00 26.70 ? 374 LEU C CB 1 ATOM 9475 C CG . LEU C 2 342 ? 58.646 17.708 4.971 1.00 26.22 ? 374 LEU C CG 1 ATOM 9476 C CD1 . LEU C 2 342 ? 58.306 18.849 4.052 1.00 25.94 ? 374 LEU C CD1 1 ATOM 9477 C CD2 . LEU C 2 342 ? 57.909 17.939 6.286 1.00 27.44 ? 374 LEU C CD2 1 ATOM 9478 N N . THR C 2 343 ? 57.513 13.977 6.634 1.00 27.53 ? 375 THR C N 1 ATOM 9479 C CA . THR C 2 343 ? 56.962 13.737 7.964 1.00 26.68 ? 375 THR C CA 1 ATOM 9480 C C . THR C 2 343 ? 57.853 12.803 8.755 1.00 26.80 ? 375 THR C C 1 ATOM 9481 O O . THR C 2 343 ? 57.936 12.929 9.971 1.00 25.97 ? 375 THR C O 1 ATOM 9482 C CB . THR C 2 343 ? 55.534 13.183 7.932 1.00 26.01 ? 375 THR C CB 1 ATOM 9483 O OG1 . THR C 2 343 ? 55.542 11.892 7.338 1.00 26.02 ? 375 THR C OG1 1 ATOM 9484 C CG2 . THR C 2 343 ? 54.589 14.100 7.167 1.00 26.14 ? 375 THR C CG2 1 ATOM 9485 N N . GLN C 2 344 ? 58.531 11.895 8.062 1.00 28.05 ? 376 GLN C N 1 ATOM 9486 C CA . GLN C 2 344 ? 59.433 10.952 8.700 1.00 31.76 ? 376 GLN C CA 1 ATOM 9487 C C . GLN C 2 344 ? 60.661 11.626 9.214 1.00 31.48 ? 376 GLN C C 1 ATOM 9488 O O . GLN C 2 344 ? 61.121 11.351 10.337 1.00 33.44 ? 376 GLN C O 1 ATOM 9489 C CB . GLN C 2 344 ? 59.935 9.903 7.718 1.00 37.49 ? 376 GLN C CB 1 ATOM 9490 C CG . GLN C 2 344 ? 58.868 9.001 7.130 1.00 43.97 ? 376 GLN C CG 1 ATOM 9491 C CD . GLN C 2 344 ? 58.156 8.196 8.197 1.00 51.29 ? 376 GLN C CD 1 ATOM 9492 O OE1 . GLN C 2 344 ? 58.649 7.141 8.631 1.00 57.33 ? 376 GLN C OE1 1 ATOM 9493 N NE2 . GLN C 2 344 ? 56.993 8.695 8.644 1.00 54.26 ? 376 GLN C NE2 1 ATOM 9494 N N . THR C 2 345 ? 61.222 12.493 8.379 1.00 30.50 ? 377 THR C N 1 ATOM 9495 C CA . THR C 2 345 ? 62.572 12.979 8.630 1.00 29.62 ? 377 THR C CA 1 ATOM 9496 C C . THR C 2 345 ? 62.547 13.871 9.892 1.00 31.20 ? 377 THR C C 1 ATOM 9497 O O . THR C 2 345 ? 63.377 13.716 10.802 1.00 30.62 ? 377 THR C O 1 ATOM 9498 C CB . THR C 2 345 ? 63.190 13.585 7.328 1.00 26.84 ? 377 THR C CB 1 ATOM 9499 O OG1 . THR C 2 345 ? 64.617 13.486 7.381 1.00 24.78 ? 377 THR C OG1 1 ATOM 9500 C CG2 . THR C 2 345 ? 62.757 14.998 7.082 1.00 25.78 ? 377 THR C CG2 1 ATOM 9501 N N . TYR C 2 346 ? 61.513 14.708 9.969 1.00 33.57 ? 378 TYR C N 1 ATOM 9502 C CA . TYR C 2 346 ? 61.336 15.689 11.031 1.00 36.00 ? 378 TYR C CA 1 ATOM 9503 C C . TYR C 2 346 ? 60.403 15.211 12.163 1.00 36.80 ? 378 TYR C C 1 ATOM 9504 O O . TYR C 2 346 ? 60.054 15.995 13.070 1.00 36.02 ? 378 TYR C O 1 ATOM 9505 C CB . TYR C 2 346 ? 60.752 16.971 10.430 1.00 38.48 ? 378 TYR C CB 1 ATOM 9506 C CG . TYR C 2 346 ? 61.634 17.686 9.451 1.00 39.28 ? 378 TYR C CG 1 ATOM 9507 C CD1 . TYR C 2 346 ? 62.812 18.280 9.867 1.00 40.94 ? 378 TYR C CD1 1 ATOM 9508 C CD2 . TYR C 2 346 ? 61.267 17.800 8.109 1.00 40.38 ? 378 TYR C CD2 1 ATOM 9509 C CE1 . TYR C 2 346 ? 63.628 18.960 8.969 1.00 45.60 ? 378 TYR C CE1 1 ATOM 9510 C CE2 . TYR C 2 346 ? 62.075 18.457 7.193 1.00 43.05 ? 378 TYR C CE2 1 ATOM 9511 C CZ . TYR C 2 346 ? 63.264 19.043 7.621 1.00 46.54 ? 378 TYR C CZ 1 ATOM 9512 O OH . TYR C 2 346 ? 64.082 19.714 6.721 1.00 43.89 ? 378 TYR C OH 1 ATOM 9513 N N . ASP C 2 347 ? 59.983 13.983 12.083 1.00 38.26 ? 379 ASP C N 1 ATOM 9514 C CA . ASP C 2 347 ? 59.173 13.443 13.103 1.00 41.91 ? 379 ASP C CA 1 ATOM 9515 C C . ASP C 2 347 ? 58.049 14.367 13.389 1.00 40.73 ? 379 ASP C C 1 ATOM 9516 O O . ASP C 2 347 ? 58.004 14.986 14.412 1.00 38.46 ? 379 ASP C O 1 ATOM 9517 C CB . ASP C 2 347 ? 60.068 13.257 14.294 1.00 47.35 ? 379 ASP C CB 1 ATOM 9518 C CG . ASP C 2 347 ? 59.340 12.844 15.520 1.00 54.21 ? 379 ASP C CG 1 ATOM 9519 O OD1 . ASP C 2 347 ? 59.141 11.634 15.683 1.00 58.44 ? 379 ASP C OD1 1 ATOM 9520 O OD2 . ASP C 2 347 ? 59.019 13.707 16.366 1.00 59.25 -1 379 ASP C OD2 1 ATOM 9521 N N . ILE C 2 348 ? 57.126 14.430 12.438 1.00 41.32 ? 380 ILE C N 1 ATOM 9522 C CA . ILE C 2 348 ? 55.887 15.242 12.499 1.00 41.18 ? 380 ILE C CA 1 ATOM 9523 C C . ILE C 2 348 ? 54.677 14.547 11.862 1.00 38.55 ? 380 ILE C C 1 ATOM 9524 O O . ILE C 2 348 ? 54.834 13.747 10.982 1.00 33.94 ? 380 ILE C O 1 ATOM 9525 C CB . ILE C 2 348 ? 56.049 16.633 11.826 1.00 41.07 ? 380 ILE C CB 1 ATOM 9526 C CG1 . ILE C 2 348 ? 56.437 16.463 10.348 1.00 43.99 ? 380 ILE C CG1 1 ATOM 9527 C CG2 . ILE C 2 348 ? 57.062 17.488 12.588 1.00 39.06 ? 380 ILE C CG2 1 ATOM 9528 C CD1 . ILE C 2 348 ? 56.472 17.753 9.550 1.00 46.33 ? 380 ILE C CD1 1 ATOM 9529 N N . GLU C 2 349 ? 53.484 14.911 12.329 1.00 40.81 ? 381 GLU C N 1 ATOM 9530 C CA . GLU C 2 349 ? 52.180 14.438 11.837 1.00 42.01 ? 381 GLU C CA 1 ATOM 9531 C C . GLU C 2 349 ? 51.904 14.553 10.332 1.00 43.66 ? 381 GLU C C 1 ATOM 9532 O O . GLU C 2 349 ? 51.616 13.571 9.660 1.00 46.52 ? 381 GLU C O 1 ATOM 9533 C CB . GLU C 2 349 ? 51.077 15.268 12.519 1.00 44.25 ? 381 GLU C CB 1 ATOM 9534 C CG . GLU C 2 349 ? 50.571 14.718 13.812 1.00 46.24 ? 381 GLU C CG 1 ATOM 9535 C CD . GLU C 2 349 ? 50.102 13.302 13.621 1.00 52.37 ? 381 GLU C CD 1 ATOM 9536 O OE1 . GLU C 2 349 ? 49.083 13.078 12.924 1.00 53.70 ? 381 GLU C OE1 1 ATOM 9537 O OE2 . GLU C 2 349 ? 50.785 12.406 14.145 1.00 60.27 -1 381 GLU C OE2 1 ATOM 9538 N N . ASP C 2 350 ? 51.916 15.779 9.829 1.00 45.82 ? 382 ASP C N 1 ATOM 9539 C CA . ASP C 2 350 ? 51.358 16.096 8.512 1.00 48.93 ? 382 ASP C CA 1 ATOM 9540 C C . ASP C 2 350 ? 52.073 17.351 7.896 1.00 49.42 ? 382 ASP C C 1 ATOM 9541 O O . ASP C 2 350 ? 53.231 17.641 8.246 1.00 54.02 ? 382 ASP C O 1 ATOM 9542 C CB . ASP C 2 350 ? 49.807 16.214 8.616 1.00 52.63 ? 382 ASP C CB 1 ATOM 9543 C CG . ASP C 2 350 ? 49.327 17.073 9.824 1.00 57.06 ? 382 ASP C CG 1 ATOM 9544 O OD1 . ASP C 2 350 ? 49.954 18.121 10.111 1.00 55.42 ? 382 ASP C OD1 1 ATOM 9545 O OD2 . ASP C 2 350 ? 48.307 16.705 10.479 1.00 58.00 -1 382 ASP C OD2 1 ATOM 9546 N N . LEU C 2 351 ? 51.440 18.055 6.951 1.00 44.29 ? 383 LEU C N 1 ATOM 9547 C CA . LEU C 2 351 ? 52.007 19.290 6.379 1.00 39.33 ? 383 LEU C CA 1 ATOM 9548 C C . LEU C 2 351 ? 51.098 20.467 6.678 1.00 38.08 ? 383 LEU C C 1 ATOM 9549 O O . LEU C 2 351 ? 51.101 21.491 5.978 1.00 32.70 ? 383 LEU C O 1 ATOM 9550 C CB . LEU C 2 351 ? 52.215 19.127 4.882 1.00 37.77 ? 383 LEU C CB 1 ATOM 9551 C CG . LEU C 2 351 ? 53.542 18.511 4.417 1.00 37.63 ? 383 LEU C CG 1 ATOM 9552 C CD1 . LEU C 2 351 ? 54.218 17.552 5.408 1.00 36.51 ? 383 LEU C CD1 1 ATOM 9553 C CD2 . LEU C 2 351 ? 53.293 17.844 3.064 1.00 37.51 ? 383 LEU C CD2 1 ATOM 9554 N N . GLN C 2 352 ? 50.334 20.294 7.755 1.00 41.28 ? 384 GLN C N 1 ATOM 9555 C CA . GLN C 2 352 ? 49.410 21.294 8.258 1.00 44.34 ? 384 GLN C CA 1 ATOM 9556 C C . GLN C 2 352 ? 50.226 22.460 8.768 1.00 44.16 ? 384 GLN C C 1 ATOM 9557 O O . GLN C 2 352 ? 51.344 22.241 9.238 1.00 47.53 ? 384 GLN C O 1 ATOM 9558 C CB . GLN C 2 352 ? 48.582 20.720 9.418 1.00 47.58 ? 384 GLN C CB 1 ATOM 9559 C CG . GLN C 2 352 ? 47.475 19.765 9.010 1.00 49.13 ? 384 GLN C CG 1 ATOM 9560 C CD . GLN C 2 352 ? 46.329 20.500 8.350 1.00 51.64 ? 384 GLN C CD 1 ATOM 9561 O OE1 . GLN C 2 352 ? 46.030 20.266 7.175 1.00 52.93 ? 384 GLN C OE1 1 ATOM 9562 N NE2 . GLN C 2 352 ? 45.714 21.442 9.085 1.00 51.18 ? 384 GLN C NE2 1 ATOM 9563 N N . PRO C 2 353 ? 49.680 23.691 8.718 1.00 41.43 ? 385 PRO C N 1 ATOM 9564 C CA . PRO C 2 353 ? 50.508 24.852 9.097 1.00 42.01 ? 385 PRO C CA 1 ATOM 9565 C C . PRO C 2 353 ? 50.897 24.920 10.604 1.00 42.69 ? 385 PRO C C 1 ATOM 9566 O O . PRO C 2 353 ? 51.917 25.514 10.964 1.00 41.41 ? 385 PRO C O 1 ATOM 9567 C CB . PRO C 2 353 ? 49.646 26.042 8.659 1.00 40.78 ? 385 PRO C CB 1 ATOM 9568 C CG . PRO C 2 353 ? 48.651 25.452 7.703 1.00 39.25 ? 385 PRO C CG 1 ATOM 9569 C CD . PRO C 2 353 ? 48.357 24.109 8.249 1.00 38.74 ? 385 PRO C CD 1 ATOM 9570 N N . GLU C 2 354 ? 50.094 24.294 11.456 1.00 44.89 ? 386 GLU C N 1 ATOM 9571 C CA . GLU C 2 354 ? 50.401 24.137 12.883 1.00 46.22 ? 386 GLU C CA 1 ATOM 9572 C C . GLU C 2 354 ? 51.590 23.177 13.016 1.00 42.06 ? 386 GLU C C 1 ATOM 9573 O O . GLU C 2 354 ? 52.470 23.355 13.856 1.00 40.20 ? 386 GLU C O 1 ATOM 9574 C CB . GLU C 2 354 ? 49.186 23.553 13.646 1.00 53.43 ? 386 GLU C CB 1 ATOM 9575 C CG . GLU C 2 354 ? 47.786 23.995 13.159 1.00 60.15 ? 386 GLU C CG 1 ATOM 9576 C CD . GLU C 2 354 ? 47.128 23.046 12.120 1.00 61.81 ? 386 GLU C CD 1 ATOM 9577 O OE1 . GLU C 2 354 ? 46.983 21.830 12.445 1.00 61.02 ? 386 GLU C OE1 1 ATOM 9578 O OE2 . GLU C 2 354 ? 46.737 23.519 10.998 1.00 53.67 -1 386 GLU C OE2 1 ATOM 9579 N N . SER C 2 355 ? 51.591 22.150 12.167 1.00 38.63 ? 387 SER C N 1 ATOM 9580 C CA . SER C 2 355 ? 52.653 21.135 12.113 1.00 35.43 ? 387 SER C CA 1 ATOM 9581 C C . SER C 2 355 ? 54.016 21.685 11.641 1.00 33.46 ? 387 SER C C 1 ATOM 9582 O O . SER C 2 355 ? 55.065 21.221 12.093 1.00 32.65 ? 387 SER C O 1 ATOM 9583 C CB . SER C 2 355 ? 52.220 19.955 11.202 1.00 34.34 ? 387 SER C CB 1 ATOM 9584 O OG . SER C 2 355 ? 51.358 19.037 11.854 1.00 32.75 ? 387 SER C OG 1 ATOM 9585 N N . LEU C 2 356 ? 53.999 22.635 10.711 1.00 31.16 ? 388 LEU C N 1 ATOM 9586 C CA . LEU C 2 356 ? 55.224 23.174 10.157 1.00 31.70 ? 388 LEU C CA 1 ATOM 9587 C C . LEU C 2 356 ? 55.726 24.368 10.947 1.00 34.76 ? 388 LEU C C 1 ATOM 9588 O O . LEU C 2 356 ? 56.931 24.536 11.104 1.00 37.73 ? 388 LEU C O 1 ATOM 9589 C CB . LEU C 2 356 ? 55.033 23.592 8.707 1.00 30.65 ? 388 LEU C CB 1 ATOM 9590 C CG . LEU C 2 356 ? 54.804 22.448 7.743 1.00 30.58 ? 388 LEU C CG 1 ATOM 9591 C CD1 . LEU C 2 356 ? 54.769 22.981 6.310 1.00 30.87 ? 388 LEU C CD1 1 ATOM 9592 C CD2 . LEU C 2 356 ? 55.869 21.373 7.914 1.00 30.99 ? 388 LEU C CD2 1 ATOM 9593 N N . TYR C 2 357 ? 54.815 25.218 11.408 1.00 35.99 ? 389 TYR C N 1 ATOM 9594 C CA . TYR C 2 357 ? 55.167 26.277 12.348 1.00 36.66 ? 389 TYR C CA 1 ATOM 9595 C C . TYR C 2 357 ? 55.855 25.729 13.612 1.00 37.17 ? 389 TYR C C 1 ATOM 9596 O O . TYR C 2 357 ? 56.685 26.422 14.208 1.00 37.05 ? 389 TYR C O 1 ATOM 9597 C CB . TYR C 2 357 ? 53.917 27.022 12.748 1.00 37.09 ? 389 TYR C CB 1 ATOM 9598 C CG . TYR C 2 357 ? 54.097 28.119 13.779 1.00 38.37 ? 389 TYR C CG 1 ATOM 9599 C CD1 . TYR C 2 357 ? 54.747 29.320 13.459 1.00 38.84 ? 389 TYR C CD1 1 ATOM 9600 C CD2 . TYR C 2 357 ? 53.550 27.980 15.058 1.00 38.32 ? 389 TYR C CD2 1 ATOM 9601 C CE1 . TYR C 2 357 ? 54.852 30.336 14.395 1.00 38.20 ? 389 TYR C CE1 1 ATOM 9602 C CE2 . TYR C 2 357 ? 53.653 28.980 15.997 1.00 38.29 ? 389 TYR C CE2 1 ATOM 9603 C CZ . TYR C 2 357 ? 54.292 30.151 15.667 1.00 38.67 ? 389 TYR C CZ 1 ATOM 9604 O OH . TYR C 2 357 ? 54.360 31.106 16.643 1.00 39.67 ? 389 TYR C OH 1 ATOM 9605 N N . GLY C 2 358 ? 55.504 24.498 14.009 1.00 37.36 ? 390 GLY C N 1 ATOM 9606 C CA . GLY C 2 358 ? 56.094 23.814 15.184 1.00 35.49 ? 390 GLY C CA 1 ATOM 9607 C C . GLY C 2 358 ? 57.480 23.249 14.942 1.00 33.45 ? 390 GLY C C 1 ATOM 9608 O O . GLY C 2 358 ? 58.326 23.247 15.831 1.00 33.23 ? 390 GLY C O 1 ATOM 9609 N N . LEU C 2 359 ? 57.698 22.743 13.730 1.00 31.71 ? 391 LEU C N 1 ATOM 9610 C CA . LEU C 2 359 ? 59.015 22.294 13.297 1.00 28.89 ? 391 LEU C CA 1 ATOM 9611 C C . LEU C 2 359 ? 59.903 23.504 13.244 1.00 27.69 ? 391 LEU C C 1 ATOM 9612 O O . LEU C 2 359 ? 61.090 23.420 13.522 1.00 28.39 ? 391 LEU C O 1 ATOM 9613 C CB . LEU C 2 359 ? 58.946 21.645 11.903 1.00 28.32 ? 391 LEU C CB 1 ATOM 9614 C CG . LEU C 2 359 ? 60.262 21.196 11.247 1.00 27.82 ? 391 LEU C CG 1 ATOM 9615 C CD1 . LEU C 2 359 ? 61.013 20.186 12.083 1.00 27.16 ? 391 LEU C CD1 1 ATOM 9616 C CD2 . LEU C 2 359 ? 59.993 20.598 9.886 1.00 28.36 ? 391 LEU C CD2 1 ATOM 9617 N N . ALA C 2 360 ? 59.322 24.632 12.873 1.00 25.25 ? 392 ALA C N 1 ATOM 9618 C CA . ALA C 2 360 ? 60.096 25.799 12.693 1.00 24.91 ? 392 ALA C CA 1 ATOM 9619 C C . ALA C 2 360 ? 60.608 26.243 14.025 1.00 25.57 ? 392 ALA C C 1 ATOM 9620 O O . ALA C 2 360 ? 61.756 26.599 14.138 1.00 24.64 ? 392 ALA C O 1 ATOM 9621 C CB . ALA C 2 360 ? 59.269 26.871 12.053 1.00 26.06 ? 392 ALA C CB 1 ATOM 9622 N N . LYS C 2 361 ? 59.772 26.191 15.055 1.00 29.12 ? 393 LYS C N 1 ATOM 9623 C CA . LYS C 2 361 ? 60.197 26.619 16.414 1.00 30.31 ? 393 LYS C CA 1 ATOM 9624 C C . LYS C 2 361 ? 61.292 25.698 16.921 1.00 29.99 ? 393 LYS C C 1 ATOM 9625 O O . LYS C 2 361 ? 62.235 26.150 17.532 1.00 29.89 ? 393 LYS C O 1 ATOM 9626 C CB . LYS C 2 361 ? 59.026 26.608 17.409 1.00 32.36 ? 393 LYS C CB 1 ATOM 9627 C CG . LYS C 2 361 ? 58.003 27.751 17.308 1.00 34.94 ? 393 LYS C CG 1 ATOM 9628 C CD . LYS C 2 361 ? 58.593 29.128 17.636 1.00 37.58 ? 393 LYS C CD 1 ATOM 9629 C CE . LYS C 2 361 ? 57.497 30.160 17.894 1.00 40.12 ? 393 LYS C CE 1 ATOM 9630 N NZ . LYS C 2 361 ? 58.029 31.456 18.423 1.00 41.58 1 393 LYS C NZ 1 ATOM 9631 N N . GLN C 2 362 ? 61.150 24.402 16.656 1.00 32.14 ? 394 GLN C N 1 ATOM 9632 C CA . GLN C 2 362 ? 62.200 23.390 16.892 1.00 33.14 ? 394 GLN C CA 1 ATOM 9633 C C . GLN C 2 362 ? 63.548 23.763 16.201 1.00 29.55 ? 394 GLN C C 1 ATOM 9634 O O . GLN C 2 362 ? 64.633 23.451 16.697 1.00 27.13 ? 394 GLN C O 1 ATOM 9635 C CB . GLN C 2 362 ? 61.708 22.001 16.388 1.00 37.46 ? 394 GLN C CB 1 ATOM 9636 C CG . GLN C 2 362 ? 61.001 21.059 17.377 1.00 40.48 ? 394 GLN C CG 1 ATOM 9637 C CD . GLN C 2 362 ? 61.176 19.561 16.987 1.00 47.66 ? 394 GLN C CD 1 ATOM 9638 O OE1 . GLN C 2 362 ? 60.608 19.097 15.983 1.00 49.21 ? 394 GLN C OE1 1 ATOM 9639 N NE2 . GLN C 2 362 ? 61.967 18.800 17.785 1.00 48.90 ? 394 GLN C NE2 1 ATOM 9640 N N . PHE C 2 363 ? 63.456 24.392 15.034 1.00 27.05 ? 395 PHE C N 1 ATOM 9641 C CA . PHE C 2 363 ? 64.608 24.909 14.363 1.00 26.45 ? 395 PHE C CA 1 ATOM 9642 C C . PHE C 2 363 ? 65.369 25.923 15.217 1.00 29.78 ? 395 PHE C C 1 ATOM 9643 O O . PHE C 2 363 ? 66.606 25.927 15.182 1.00 30.03 ? 395 PHE C O 1 ATOM 9644 C CB . PHE C 2 363 ? 64.216 25.579 13.047 1.00 25.30 ? 395 PHE C CB 1 ATOM 9645 C CG . PHE C 2 363 ? 63.871 24.634 11.919 1.00 24.81 ? 395 PHE C CG 1 ATOM 9646 C CD1 . PHE C 2 363 ? 64.037 23.251 12.023 1.00 25.37 ? 395 PHE C CD1 1 ATOM 9647 C CD2 . PHE C 2 363 ? 63.420 25.154 10.715 1.00 23.92 ? 395 PHE C CD2 1 ATOM 9648 C CE1 . PHE C 2 363 ? 63.724 22.412 10.958 1.00 25.27 ? 395 PHE C CE1 1 ATOM 9649 C CE2 . PHE C 2 363 ? 63.102 24.319 9.664 1.00 24.31 ? 395 PHE C CE2 1 ATOM 9650 C CZ . PHE C 2 363 ? 63.257 22.945 9.781 1.00 24.46 ? 395 PHE C CZ 1 ATOM 9651 N N . THR C 2 364 ? 64.642 26.762 15.984 1.00 35.21 ? 396 THR C N 1 ATOM 9652 C CA . THR C 2 364 ? 65.212 27.898 16.809 1.00 36.55 ? 396 THR C CA 1 ATOM 9653 C C . THR C 2 364 ? 66.011 27.530 18.115 1.00 35.68 ? 396 THR C C 1 ATOM 9654 O O . THR C 2 364 ? 66.765 28.360 18.628 1.00 38.83 ? 396 THR C O 1 ATOM 9655 C CB . THR C 2 364 ? 64.127 28.984 17.150 1.00 38.20 ? 396 THR C CB 1 ATOM 9656 O OG1 . THR C 2 364 ? 63.146 28.467 18.052 1.00 39.72 ? 396 THR C OG1 1 ATOM 9657 C CG2 . THR C 2 364 ? 63.393 29.470 15.918 1.00 39.01 ? 396 THR C CG2 1 ATOM 9658 N N . ILE C 2 365 ? 65.824 26.310 18.633 1.00 33.70 ? 397 ILE C N 1 ATOM 9659 C CA . ILE C 2 365 ? 66.704 25.683 19.644 1.00 32.71 ? 397 ILE C CA 1 ATOM 9660 C C . ILE C 2 365 ? 68.182 25.876 19.292 1.00 34.53 ? 397 ILE C C 1 ATOM 9661 O O . ILE C 2 365 ? 68.557 25.801 18.136 1.00 33.01 ? 397 ILE C O 1 ATOM 9662 C CB . ILE C 2 365 ? 66.396 24.158 19.738 1.00 31.50 ? 397 ILE C CB 1 ATOM 9663 C CG1 . ILE C 2 365 ? 65.039 23.938 20.439 1.00 30.86 ? 397 ILE C CG1 1 ATOM 9664 C CG2 . ILE C 2 365 ? 67.536 23.368 20.405 1.00 30.18 ? 397 ILE C CG2 1 ATOM 9665 C CD1 . ILE C 2 365 ? 64.463 22.544 20.308 1.00 29.75 ? 397 ILE C CD1 1 ATOM 9666 N N . LEU C 2 366 ? 69.023 26.129 20.290 1.00 38.64 ? 398 LEU C N 1 ATOM 9667 C CA . LEU C 2 366 ? 70.446 26.312 20.039 1.00 43.30 ? 398 LEU C CA 1 ATOM 9668 C C . LEU C 2 366 ? 70.925 25.015 19.428 1.00 47.62 ? 398 LEU C C 1 ATOM 9669 O O . LEU C 2 366 ? 70.423 23.955 19.780 1.00 53.05 ? 398 LEU C O 1 ATOM 9670 C CB . LEU C 2 366 ? 71.217 26.619 21.331 1.00 46.15 ? 398 LEU C CB 1 ATOM 9671 C CG . LEU C 2 366 ? 71.062 27.977 22.080 1.00 47.70 ? 398 LEU C CG 1 ATOM 9672 C CD1 . LEU C 2 366 ? 70.178 29.034 21.393 1.00 46.52 ? 398 LEU C CD1 1 ATOM 9673 C CD2 . LEU C 2 366 ? 70.594 27.727 23.522 1.00 46.65 ? 398 LEU C CD2 1 ATOM 9674 N N . ASP C 2 367 ? 71.874 25.125 18.502 1.00 54.01 ? 399 ASP C N 1 ATOM 9675 C CA . ASP C 2 367 ? 72.374 24.015 17.652 1.00 59.88 ? 399 ASP C CA 1 ATOM 9676 C C . ASP C 2 367 ? 71.313 22.926 17.296 1.00 55.73 ? 399 ASP C C 1 ATOM 9677 O O . ASP C 2 367 ? 71.554 21.723 17.500 1.00 56.58 ? 399 ASP C O 1 ATOM 9678 C CB . ASP C 2 367 ? 73.711 23.422 18.227 1.00 66.96 ? 399 ASP C CB 1 ATOM 9679 C CG . ASP C 2 367 ? 74.959 24.387 18.037 1.00 78.07 ? 399 ASP C CG 1 ATOM 9680 O OD1 . ASP C 2 367 ? 74.968 25.492 18.642 1.00 87.30 ? 399 ASP C OD1 1 ATOM 9681 O OD2 . ASP C 2 367 ? 75.936 24.045 17.299 1.00 74.64 -1 399 ASP C OD2 1 ATOM 9682 N N . SER C 2 368 ? 70.161 23.345 16.742 1.00 49.51 ? 400 SER C N 1 ATOM 9683 C CA . SER C 2 368 ? 69.044 22.408 16.497 1.00 42.75 ? 400 SER C CA 1 ATOM 9684 C C . SER C 2 368 ? 69.439 21.424 15.463 1.00 41.32 ? 400 SER C C 1 ATOM 9685 O O . SER C 2 368 ? 69.747 21.801 14.345 1.00 37.82 ? 400 SER C O 1 ATOM 9686 C CB . SER C 2 368 ? 67.758 23.069 15.997 1.00 39.13 ? 400 SER C CB 1 ATOM 9687 O OG . SER C 2 368 ? 66.748 22.084 15.816 1.00 33.84 ? 400 SER C OG 1 ATOM 9688 N N . LYS C 2 369 ? 69.404 20.166 15.867 1.00 42.68 ? 401 LYS C N 1 ATOM 9689 C CA . LYS C 2 369 ? 69.586 19.031 14.982 1.00 45.04 ? 401 LYS C CA 1 ATOM 9690 C C . LYS C 2 369 ? 68.663 19.065 13.758 1.00 41.49 ? 401 LYS C C 1 ATOM 9691 O O . LYS C 2 369 ? 69.028 18.595 12.691 1.00 39.59 ? 401 LYS C O 1 ATOM 9692 C CB . LYS C 2 369 ? 69.270 17.760 15.773 1.00 52.21 ? 401 LYS C CB 1 ATOM 9693 C CG . LYS C 2 369 ? 70.192 16.587 15.508 1.00 58.20 ? 401 LYS C CG 1 ATOM 9694 C CD . LYS C 2 369 ? 71.267 16.484 16.580 1.00 60.70 ? 401 LYS C CD 1 ATOM 9695 C CE . LYS C 2 369 ? 72.385 15.573 16.109 1.00 64.38 ? 401 LYS C CE 1 ATOM 9696 N NZ . LYS C 2 369 ? 73.623 15.921 16.842 1.00 69.79 1 401 LYS C NZ 1 ATOM 9697 N N . GLN C 2 370 ? 67.449 19.591 13.939 1.00 41.52 ? 402 GLN C N 1 ATOM 9698 C CA . GLN C 2 370 ? 66.409 19.640 12.877 1.00 38.22 ? 402 GLN C CA 1 ATOM 9699 C C . GLN C 2 370 ? 66.763 20.638 11.812 1.00 33.56 ? 402 GLN C C 1 ATOM 9700 O O . GLN C 2 370 ? 66.736 20.349 10.623 1.00 33.14 ? 402 GLN C O 1 ATOM 9701 C CB . GLN C 2 370 ? 65.047 20.050 13.452 1.00 38.98 ? 402 GLN C CB 1 ATOM 9702 C CG . GLN C 2 370 ? 64.423 19.033 14.383 1.00 39.93 ? 402 GLN C CG 1 ATOM 9703 C CD . GLN C 2 370 ? 63.904 17.826 13.631 1.00 43.17 ? 402 GLN C CD 1 ATOM 9704 O OE1 . GLN C 2 370 ? 64.636 17.138 12.882 1.00 44.04 ? 402 GLN C OE1 1 ATOM 9705 N NE2 . GLN C 2 370 ? 62.620 17.558 13.816 1.00 45.99 ? 402 GLN C NE2 1 ATOM 9706 N N . PHE C 2 371 ? 67.095 21.836 12.240 1.00 29.45 ? 403 PHE C N 1 ATOM 9707 C CA . PHE C 2 371 ? 67.580 22.802 11.290 1.00 27.79 ? 403 PHE C CA 1 ATOM 9708 C C . PHE C 2 371 ? 68.792 22.279 10.495 1.00 27.39 ? 403 PHE C C 1 ATOM 9709 O O . PHE C 2 371 ? 68.959 22.605 9.301 1.00 26.62 ? 403 PHE C O 1 ATOM 9710 C CB . PHE C 2 371 ? 67.947 24.094 11.997 1.00 25.56 ? 403 PHE C CB 1 ATOM 9711 C CG . PHE C 2 371 ? 68.381 25.161 11.069 1.00 22.59 ? 403 PHE C CG 1 ATOM 9712 C CD1 . PHE C 2 371 ? 67.468 25.869 10.361 1.00 21.91 ? 403 PHE C CD1 1 ATOM 9713 C CD2 . PHE C 2 371 ? 69.705 25.409 10.888 1.00 22.07 ? 403 PHE C CD2 1 ATOM 9714 C CE1 . PHE C 2 371 ? 67.868 26.839 9.497 1.00 22.30 ? 403 PHE C CE1 1 ATOM 9715 C CE2 . PHE C 2 371 ? 70.130 26.384 10.032 1.00 21.97 ? 403 PHE C CE2 1 ATOM 9716 C CZ . PHE C 2 371 ? 69.208 27.101 9.332 1.00 22.74 ? 403 PHE C CZ 1 ATOM 9717 N N . ILE C 2 372 ? 69.634 21.486 11.142 1.00 26.03 ? 404 ILE C N 1 ATOM 9718 C CA . ILE C 2 372 ? 70.821 21.047 10.460 1.00 28.43 ? 404 ILE C CA 1 ATOM 9719 C C . ILE C 2 372 ? 70.352 20.231 9.239 1.00 30.35 ? 404 ILE C C 1 ATOM 9720 O O . ILE C 2 372 ? 70.754 20.507 8.097 1.00 29.73 ? 404 ILE C O 1 ATOM 9721 C CB . ILE C 2 372 ? 71.813 20.235 11.344 1.00 28.63 ? 404 ILE C CB 1 ATOM 9722 C CG1 . ILE C 2 372 ? 71.965 20.787 12.763 1.00 30.06 ? 404 ILE C CG1 1 ATOM 9723 C CG2 . ILE C 2 372 ? 73.194 20.222 10.704 1.00 28.59 ? 404 ILE C CG2 1 ATOM 9724 C CD1 . ILE C 2 372 ? 72.363 22.258 12.878 1.00 30.73 ? 404 ILE C CD1 1 ATOM 9725 N N . LYS C 2 373 ? 69.487 19.245 9.485 1.00 31.75 ? 405 LYS C N 1 ATOM 9726 C CA . LYS C 2 373 ? 68.885 18.462 8.404 1.00 32.13 ? 405 LYS C CA 1 ATOM 9727 C C . LYS C 2 373 ? 68.450 19.428 7.332 1.00 31.23 ? 405 LYS C C 1 ATOM 9728 O O . LYS C 2 373 ? 68.827 19.285 6.176 1.00 27.44 ? 405 LYS C O 1 ATOM 9729 C CB . LYS C 2 373 ? 67.630 17.685 8.881 1.00 32.93 ? 405 LYS C CB 1 ATOM 9730 C CG . LYS C 2 373 ? 67.825 16.199 9.073 1.00 33.62 ? 405 LYS C CG 1 ATOM 9731 C CD . LYS C 2 373 ? 66.557 15.512 9.563 1.00 35.86 ? 405 LYS C CD 1 ATOM 9732 C CE . LYS C 2 373 ? 66.904 14.179 10.256 1.00 38.17 ? 405 LYS C CE 1 ATOM 9733 N NZ . LYS C 2 373 ? 65.795 13.184 10.429 1.00 38.02 1 405 LYS C NZ 1 ATOM 9734 N N . TYR C 2 374 ? 67.645 20.410 7.769 1.00 32.52 ? 406 TYR C N 1 ATOM 9735 C CA . TYR C 2 374 ? 66.869 21.290 6.885 1.00 33.01 ? 406 TYR C CA 1 ATOM 9736 C C . TYR C 2 374 ? 67.765 22.079 5.954 1.00 35.45 ? 406 TYR C C 1 ATOM 9737 O O . TYR C 2 374 ? 67.348 22.382 4.828 1.00 39.37 ? 406 TYR C O 1 ATOM 9738 C CB . TYR C 2 374 ? 65.922 22.222 7.688 1.00 30.78 ? 406 TYR C CB 1 ATOM 9739 C CG . TYR C 2 374 ? 65.225 23.310 6.869 1.00 28.04 ? 406 TYR C CG 1 ATOM 9740 C CD1 . TYR C 2 374 ? 63.981 23.101 6.258 1.00 27.69 ? 406 TYR C CD1 1 ATOM 9741 C CD2 . TYR C 2 374 ? 65.816 24.540 6.716 1.00 26.81 ? 406 TYR C CD2 1 ATOM 9742 C CE1 . TYR C 2 374 ? 63.373 24.104 5.515 1.00 26.96 ? 406 TYR C CE1 1 ATOM 9743 C CE2 . TYR C 2 374 ? 65.228 25.528 5.978 1.00 26.41 ? 406 TYR C CE2 1 ATOM 9744 C CZ . TYR C 2 374 ? 64.026 25.313 5.392 1.00 26.55 ? 406 TYR C CZ 1 ATOM 9745 O OH . TYR C 2 374 ? 63.539 26.374 4.706 1.00 28.17 ? 406 TYR C OH 1 ATOM 9746 N N . TYR C 2 375 ? 68.983 22.394 6.406 1.00 37.28 ? 407 TYR C N 1 ATOM 9747 C CA . TYR C 2 375 ? 69.949 23.156 5.586 1.00 36.86 ? 407 TYR C CA 1 ATOM 9748 C C . TYR C 2 375 ? 70.766 22.240 4.613 1.00 37.99 ? 407 TYR C C 1 ATOM 9749 O O . TYR C 2 375 ? 71.054 22.598 3.443 1.00 35.38 ? 407 TYR C O 1 ATOM 9750 C CB . TYR C 2 375 ? 70.836 24.000 6.518 1.00 34.51 ? 407 TYR C CB 1 ATOM 9751 C CG . TYR C 2 375 ? 71.444 25.226 5.862 1.00 31.70 ? 407 TYR C CG 1 ATOM 9752 C CD1 . TYR C 2 375 ? 70.674 26.334 5.540 1.00 29.64 ? 407 TYR C CD1 1 ATOM 9753 C CD2 . TYR C 2 375 ? 72.795 25.270 5.581 1.00 31.80 ? 407 TYR C CD2 1 ATOM 9754 C CE1 . TYR C 2 375 ? 71.239 27.442 4.951 1.00 28.77 ? 407 TYR C CE1 1 ATOM 9755 C CE2 . TYR C 2 375 ? 73.373 26.378 4.993 1.00 31.28 ? 407 TYR C CE2 1 ATOM 9756 C CZ . TYR C 2 375 ? 72.595 27.458 4.677 1.00 29.55 ? 407 TYR C CZ 1 ATOM 9757 O OH . TYR C 2 375 ? 73.221 28.540 4.100 1.00 29.03 ? 407 TYR C OH 1 ATOM 9758 N N . ASN C 2 376 ? 71.109 21.058 5.117 1.00 40.62 ? 408 ASN C N 1 ATOM 9759 C CA . ASN C 2 376 ? 71.662 19.973 4.314 1.00 43.44 ? 408 ASN C CA 1 ATOM 9760 C C . ASN C 2 376 ? 70.768 19.741 3.102 1.00 41.07 ? 408 ASN C C 1 ATOM 9761 O O . ASN C 2 376 ? 71.254 19.648 1.990 1.00 40.93 ? 408 ASN C O 1 ATOM 9762 C CB . ASN C 2 376 ? 71.735 18.677 5.159 1.00 48.63 ? 408 ASN C CB 1 ATOM 9763 C CG . ASN C 2 376 ? 72.744 18.751 6.323 1.00 54.07 ? 408 ASN C CG 1 ATOM 9764 O OD1 . ASN C 2 376 ? 73.759 19.465 6.262 1.00 59.25 ? 408 ASN C OD1 1 ATOM 9765 N ND2 . ASN C 2 376 ? 72.463 17.990 7.397 1.00 54.57 ? 408 ASN C ND2 1 ATOM 9766 N N . TYR C 2 377 ? 69.460 19.683 3.367 1.00 41.66 ? 409 TYR C N 1 ATOM 9767 C CA . TYR C 2 377 ? 68.387 19.455 2.390 1.00 42.59 ? 409 TYR C CA 1 ATOM 9768 C C . TYR C 2 377 ? 67.930 20.714 1.637 1.00 42.08 ? 409 TYR C C 1 ATOM 9769 O O . TYR C 2 377 ? 67.230 20.595 0.637 1.00 43.30 ? 409 TYR C O 1 ATOM 9770 C CB . TYR C 2 377 ? 67.131 18.920 3.102 1.00 46.94 ? 409 TYR C CB 1 ATOM 9771 C CG . TYR C 2 377 ? 67.141 17.477 3.615 1.00 53.20 ? 409 TYR C CG 1 ATOM 9772 C CD1 . TYR C 2 377 ? 67.986 16.491 3.056 1.00 56.98 ? 409 TYR C CD1 1 ATOM 9773 C CD2 . TYR C 2 377 ? 66.242 17.072 4.626 1.00 53.85 ? 409 TYR C CD2 1 ATOM 9774 C CE1 . TYR C 2 377 ? 67.963 15.170 3.511 1.00 54.47 ? 409 TYR C CE1 1 ATOM 9775 C CE2 . TYR C 2 377 ? 66.211 15.751 5.075 1.00 53.83 ? 409 TYR C CE2 1 ATOM 9776 C CZ . TYR C 2 377 ? 67.074 14.811 4.517 1.00 52.39 ? 409 TYR C CZ 1 ATOM 9777 O OH . TYR C 2 377 ? 67.059 13.515 4.957 1.00 48.46 ? 409 TYR C OH 1 ATOM 9778 N N . PHE C 2 378 ? 68.259 21.906 2.139 1.00 40.09 ? 410 PHE C N 1 ATOM 9779 C CA . PHE C 2 378 ? 67.966 23.180 1.454 1.00 36.14 ? 410 PHE C CA 1 ATOM 9780 C C . PHE C 2 378 ? 68.741 23.323 0.112 1.00 35.81 ? 410 PHE C C 1 ATOM 9781 O O . PHE C 2 378 ? 68.161 23.790 -0.869 1.00 37.52 ? 410 PHE C O 1 ATOM 9782 C CB . PHE C 2 378 ? 68.241 24.350 2.417 1.00 35.24 ? 410 PHE C CB 1 ATOM 9783 C CG . PHE C 2 378 ? 68.168 25.718 1.786 1.00 35.20 ? 410 PHE C CG 1 ATOM 9784 C CD1 . PHE C 2 378 ? 66.954 26.341 1.563 1.00 36.01 ? 410 PHE C CD1 1 ATOM 9785 C CD2 . PHE C 2 378 ? 69.326 26.398 1.450 1.00 35.02 ? 410 PHE C CD2 1 ATOM 9786 C CE1 . PHE C 2 378 ? 66.903 27.596 0.984 1.00 35.97 ? 410 PHE C CE1 1 ATOM 9787 C CE2 . PHE C 2 378 ? 69.280 27.657 0.886 1.00 34.87 ? 410 PHE C CE2 1 ATOM 9788 C CZ . PHE C 2 378 ? 68.068 28.260 0.656 1.00 35.60 ? 410 PHE C CZ 1 ATOM 9789 N N . PHE C 2 379 ? 70.019 22.903 0.053 1.00 32.55 ? 411 PHE C N 1 ATOM 9790 C CA . PHE C 2 379 ? 70.783 22.824 -1.219 1.00 29.74 ? 411 PHE C CA 1 ATOM 9791 C C . PHE C 2 379 ? 70.709 21.441 -1.837 1.00 27.80 ? 411 PHE C C 1 ATOM 9792 O O . PHE C 2 379 ? 71.625 21.014 -2.539 1.00 26.93 ? 411 PHE C O 1 ATOM 9793 C CB . PHE C 2 379 ? 72.252 23.134 -0.990 1.00 30.83 ? 411 PHE C CB 1 ATOM 9794 C CG . PHE C 2 379 ? 72.489 24.445 -0.326 1.00 32.95 ? 411 PHE C CG 1 ATOM 9795 C CD1 . PHE C 2 379 ? 72.474 25.628 -1.069 1.00 32.36 ? 411 PHE C CD1 1 ATOM 9796 C CD2 . PHE C 2 379 ? 72.725 24.511 1.063 1.00 32.92 ? 411 PHE C CD2 1 ATOM 9797 C CE1 . PHE C 2 379 ? 72.683 26.855 -0.439 1.00 32.21 ? 411 PHE C CE1 1 ATOM 9798 C CE2 . PHE C 2 379 ? 72.946 25.730 1.680 1.00 31.21 ? 411 PHE C CE2 1 ATOM 9799 C CZ . PHE C 2 379 ? 72.923 26.904 0.932 1.00 30.98 ? 411 PHE C CZ 1 ATOM 9800 N N . VAL C 2 380 ? 69.614 20.755 -1.528 1.00 26.56 ? 412 VAL C N 1 ATOM 9801 C CA . VAL C 2 380 ? 69.252 19.403 -1.987 1.00 24.85 ? 412 VAL C CA 1 ATOM 9802 C C . VAL C 2 380 ? 70.301 18.292 -1.707 1.00 25.12 ? 412 VAL C C 1 ATOM 9803 O O . VAL C 2 380 ? 70.608 17.470 -2.563 1.00 24.66 ? 412 VAL C O 1 ATOM 9804 C CB . VAL C 2 380 ? 68.734 19.452 -3.441 1.00 22.51 ? 412 VAL C CB 1 ATOM 9805 C CG1 . VAL C 2 380 ? 68.085 18.138 -3.804 1.00 22.74 ? 412 VAL C CG1 1 ATOM 9806 C CG2 . VAL C 2 380 ? 67.732 20.574 -3.605 1.00 21.16 ? 412 VAL C CG2 1 ATOM 9807 N N . SER C 2 381 ? 70.799 18.258 -0.475 1.00 26.79 ? 413 SER C N 1 ATOM 9808 C CA . SER C 2 381 ? 71.886 17.356 -0.075 1.00 30.12 ? 413 SER C CA 1 ATOM 9809 C C . SER C 2 381 ? 73.213 17.556 -0.907 1.00 32.77 ? 413 SER C C 1 ATOM 9810 O O . SER C 2 381 ? 74.110 16.678 -0.880 1.00 35.16 ? 413 SER C O 1 ATOM 9811 C CB . SER C 2 381 ? 71.413 15.865 -0.077 1.00 30.58 ? 413 SER C CB 1 ATOM 9812 O OG . SER C 2 381 ? 70.501 15.538 0.978 1.00 30.34 ? 413 SER C OG 1 ATOM 9813 N N . TYR C 2 382 ? 73.356 18.700 -1.603 1.00 33.73 ? 414 TYR C N 1 ATOM 9814 C CA . TYR C 2 382 ? 74.482 18.920 -2.546 1.00 35.52 ? 414 TYR C CA 1 ATOM 9815 C C . TYR C 2 382 ? 75.818 18.574 -1.864 1.00 39.77 ? 414 TYR C C 1 ATOM 9816 O O . TYR C 2 382 ? 76.426 17.532 -2.173 1.00 37.63 ? 414 TYR C O 1 ATOM 9817 C CB . TYR C 2 382 ? 74.472 20.360 -3.188 1.00 34.61 ? 414 TYR C CB 1 ATOM 9818 C CG . TYR C 2 382 ? 75.774 20.736 -3.960 1.00 32.50 ? 414 TYR C CG 1 ATOM 9819 C CD1 . TYR C 2 382 ? 76.161 20.032 -5.120 1.00 30.76 ? 414 TYR C CD1 1 ATOM 9820 C CD2 . TYR C 2 382 ? 76.605 21.778 -3.514 1.00 29.88 ? 414 TYR C CD2 1 ATOM 9821 C CE1 . TYR C 2 382 ? 77.329 20.343 -5.783 1.00 29.88 ? 414 TYR C CE1 1 ATOM 9822 C CE2 . TYR C 2 382 ? 77.765 22.095 -4.172 1.00 28.84 ? 414 TYR C CE2 1 ATOM 9823 C CZ . TYR C 2 382 ? 78.127 21.370 -5.293 1.00 28.80 ? 414 TYR C CZ 1 ATOM 9824 O OH . TYR C 2 382 ? 79.285 21.675 -5.933 1.00 25.48 ? 414 TYR C OH 1 ATOM 9825 N N . ASP C 2 383 ? 76.241 19.453 -0.945 1.00 49.32 ? 415 ASP C N 1 ATOM 9826 C CA . ASP C 2 383 ? 77.284 19.171 0.046 1.00 57.73 ? 415 ASP C CA 1 ATOM 9827 C C . ASP C 2 383 ? 76.591 18.884 1.384 1.00 62.93 ? 415 ASP C C 1 ATOM 9828 O O . ASP C 2 383 ? 75.663 19.616 1.792 1.00 62.27 ? 415 ASP C O 1 ATOM 9829 C CB . ASP C 2 383 ? 78.271 20.342 0.196 1.00 59.45 ? 415 ASP C CB 1 ATOM 9830 C CG . ASP C 2 383 ? 79.459 19.999 1.104 1.00 58.63 ? 415 ASP C CG 1 ATOM 9831 O OD1 . ASP C 2 383 ? 79.935 18.848 1.039 1.00 54.07 ? 415 ASP C OD1 1 ATOM 9832 O OD2 . ASP C 2 383 ? 79.916 20.878 1.877 1.00 60.81 -1 415 ASP C OD2 1 ATOM 9833 N N . SER C 2 384 ? 77.030 17.800 2.030 1.00 66.59 ? 416 SER C N 1 ATOM 9834 C CA . SER C 2 384 ? 76.433 17.322 3.271 1.00 70.14 ? 416 SER C CA 1 ATOM 9835 C C . SER C 2 384 ? 77.321 17.619 4.484 1.00 70.52 ? 416 SER C C 1 ATOM 9836 O O . SER C 2 384 ? 76.859 17.579 5.632 1.00 69.74 ? 416 SER C O 1 ATOM 9837 C CB . SER C 2 384 ? 76.116 15.833 3.150 1.00 74.35 ? 416 SER C CB 1 ATOM 9838 O OG . SER C 2 384 ? 74.912 15.642 2.421 1.00 77.07 ? 416 SER C OG 1 ATOM 9839 N N . SER C 2 385 ? 78.585 17.943 4.224 1.00 68.93 ? 417 SER C N 1 ATOM 9840 C CA . SER C 2 385 ? 79.397 18.671 5.195 1.00 67.32 ? 417 SER C CA 1 ATOM 9841 C C . SER C 2 385 ? 79.227 20.216 5.021 1.00 68.69 ? 417 SER C C 1 ATOM 9842 O O . SER C 2 385 ? 80.148 20.997 5.300 1.00 69.00 ? 417 SER C O 1 ATOM 9843 C CB . SER C 2 385 ? 80.863 18.236 5.077 1.00 64.61 ? 417 SER C CB 1 ATOM 9844 O OG . SER C 2 385 ? 81.531 18.946 4.057 1.00 61.29 ? 417 SER C OG 1 ATOM 9845 N N . VAL C 2 386 ? 78.025 20.644 4.683 1.00 62.84 ? 418 VAL C N 1 ATOM 9846 C CA . VAL C 2 386 ? 77.742 22.042 4.566 1.00 59.40 ? 418 VAL C CA 1 ATOM 9847 C C . VAL C 2 386 ? 77.404 22.516 5.950 1.00 55.20 ? 418 VAL C C 1 ATOM 9848 O O . VAL C 2 386 ? 76.783 21.811 6.699 1.00 55.58 ? 418 VAL C O 1 ATOM 9849 C CB . VAL C 2 386 ? 76.474 22.224 3.751 1.00 64.13 ? 418 VAL C CB 1 ATOM 9850 C CG1 . VAL C 2 386 ? 75.383 21.352 4.313 1.00 64.90 ? 418 VAL C CG1 1 ATOM 9851 C CG2 . VAL C 2 386 ? 76.014 23.667 3.746 1.00 66.05 ? 418 VAL C CG2 1 ATOM 9852 N N . THR C 2 387 ? 77.774 23.735 6.272 1.00 48.21 ? 419 THR C N 1 ATOM 9853 C CA . THR C 2 387 ? 77.476 24.344 7.575 1.00 41.70 ? 419 THR C CA 1 ATOM 9854 C C . THR C 2 387 ? 76.819 25.720 7.441 1.00 38.13 ? 419 THR C C 1 ATOM 9855 O O . THR C 2 387 ? 76.626 26.241 6.344 1.00 37.23 ? 419 THR C O 1 ATOM 9856 C CB . THR C 2 387 ? 78.752 24.475 8.424 1.00 42.24 ? 419 THR C CB 1 ATOM 9857 O OG1 . THR C 2 387 ? 78.401 24.793 9.765 1.00 39.57 ? 419 THR C OG1 1 ATOM 9858 C CG2 . THR C 2 387 ? 79.677 25.576 7.885 1.00 44.11 ? 419 THR C CG2 1 ATOM 9859 N N . CYS C 2 388 ? 76.508 26.307 8.583 1.00 37.81 ? 420 CYS C N 1 ATOM 9860 C CA . CYS C 2 388 ? 75.711 27.530 8.670 1.00 40.59 ? 420 CYS C CA 1 ATOM 9861 C C . CYS C 2 388 ? 76.034 28.303 9.974 1.00 39.46 ? 420 CYS C C 1 ATOM 9862 O O . CYS C 2 388 ? 76.126 27.674 11.017 1.00 41.04 ? 420 CYS C O 1 ATOM 9863 C CB . CYS C 2 388 ? 74.224 27.159 8.665 1.00 41.48 ? 420 CYS C CB 1 ATOM 9864 S SG . CYS C 2 388 ? 73.158 28.607 8.462 1.00 50.80 ? 420 CYS C SG 1 ATOM 9865 N N . ASP C 2 389 ? 76.200 29.635 9.926 1.00 37.35 ? 421 ASP C N 1 ATOM 9866 C CA . ASP C 2 389 ? 76.527 30.450 11.127 1.00 35.59 ? 421 ASP C CA 1 ATOM 9867 C C . ASP C 2 389 ? 75.284 31.163 11.644 1.00 35.42 ? 421 ASP C C 1 ATOM 9868 O O . ASP C 2 389 ? 74.306 31.214 10.932 1.00 34.58 ? 421 ASP C O 1 ATOM 9869 C CB . ASP C 2 389 ? 77.606 31.475 10.807 1.00 34.93 ? 421 ASP C CB 1 ATOM 9870 C CG . ASP C 2 389 ? 77.094 32.549 9.938 1.00 34.12 ? 421 ASP C CG 1 ATOM 9871 O OD1 . ASP C 2 389 ? 76.536 32.178 8.907 1.00 37.18 ? 421 ASP C OD1 1 ATOM 9872 O OD2 . ASP C 2 389 ? 77.206 33.737 10.271 1.00 33.38 -1 421 ASP C OD2 1 ATOM 9873 N N . LYS C 2 390 ? 75.330 31.724 12.861 1.00 39.53 ? 422 LYS C N 1 ATOM 9874 C CA . LYS C 2 390 ? 74.099 32.210 13.565 1.00 43.85 ? 422 LYS C CA 1 ATOM 9875 C C . LYS C 2 390 ? 73.246 33.154 12.700 1.00 45.47 ? 422 LYS C C 1 ATOM 9876 O O . LYS C 2 390 ? 72.011 33.093 12.762 1.00 49.07 ? 422 LYS C O 1 ATOM 9877 C CB . LYS C 2 390 ? 74.368 32.957 14.895 1.00 45.31 ? 422 LYS C CB 1 ATOM 9878 C CG . LYS C 2 390 ? 75.338 32.346 15.896 1.00 48.48 ? 422 LYS C CG 1 ATOM 9879 C CD . LYS C 2 390 ? 76.054 33.431 16.721 1.00 54.12 ? 422 LYS C CD 1 ATOM 9880 C CE . LYS C 2 390 ? 76.670 34.557 15.861 1.00 55.50 ? 422 LYS C CE 1 ATOM 9881 N NZ . LYS C 2 390 ? 77.875 35.246 16.422 1.00 55.25 1 422 LYS C NZ 1 ATOM 9882 N N . THR C 2 391 ? 73.898 34.027 11.920 1.00 43.16 ? 423 THR C N 1 ATOM 9883 C CA . THR C 2 391 ? 73.205 35.022 11.087 1.00 40.66 ? 423 THR C CA 1 ATOM 9884 C C . THR C 2 391 ? 72.402 34.365 9.937 1.00 43.83 ? 423 THR C C 1 ATOM 9885 O O . THR C 2 391 ? 71.159 34.462 9.920 1.00 42.98 ? 423 THR C O 1 ATOM 9886 C CB . THR C 2 391 ? 74.213 36.055 10.579 1.00 37.94 ? 423 THR C CB 1 ATOM 9887 O OG1 . THR C 2 391 ? 75.081 36.379 11.658 1.00 34.80 ? 423 THR C OG1 1 ATOM 9888 C CG2 . THR C 2 391 ? 73.534 37.308 10.116 1.00 37.28 ? 423 THR C CG2 1 ATOM 9889 N N . CYS C 2 392 ? 73.087 33.664 9.021 1.00 45.70 ? 424 CYS C N 1 ATOM 9890 C CA . CYS C 2 392 ? 72.405 32.818 8.020 1.00 48.20 ? 424 CYS C CA 1 ATOM 9891 C C . CYS C 2 392 ? 71.231 32.089 8.627 1.00 44.35 ? 424 CYS C C 1 ATOM 9892 O O . CYS C 2 392 ? 70.118 32.185 8.118 1.00 48.26 ? 424 CYS C O 1 ATOM 9893 C CB . CYS C 2 392 ? 73.343 31.801 7.372 1.00 52.14 ? 424 CYS C CB 1 ATOM 9894 S SG . CYS C 2 392 ? 74.229 32.511 5.958 1.00 68.48 ? 424 CYS C SG 1 ATOM 9895 N N . LYS C 2 393 ? 71.466 31.385 9.729 1.00 38.78 ? 425 LYS C N 1 ATOM 9896 C CA . LYS C 2 393 ? 70.377 30.725 10.422 1.00 35.53 ? 425 LYS C CA 1 ATOM 9897 C C . LYS C 2 393 ? 69.281 31.692 10.876 1.00 34.60 ? 425 LYS C C 1 ATOM 9898 O O . LYS C 2 393 ? 68.116 31.361 10.762 1.00 38.16 ? 425 LYS C O 1 ATOM 9899 C CB . LYS C 2 393 ? 70.871 29.898 11.602 1.00 34.57 ? 425 LYS C CB 1 ATOM 9900 C CG . LYS C 2 393 ? 69.726 29.439 12.501 1.00 35.52 ? 425 LYS C CG 1 ATOM 9901 C CD . LYS C 2 393 ? 70.067 28.285 13.416 1.00 34.00 ? 425 LYS C CD 1 ATOM 9902 C CE . LYS C 2 393 ? 68.966 28.091 14.446 1.00 33.52 ? 425 LYS C CE 1 ATOM 9903 N NZ . LYS C 2 393 ? 69.161 26.775 15.112 1.00 34.39 1 425 LYS C NZ 1 ATOM 9904 N N . ALA C 2 394 ? 69.623 32.863 11.394 1.00 31.38 ? 426 ALA C N 1 ATOM 9905 C CA . ALA C 2 394 ? 68.598 33.795 11.804 1.00 31.08 ? 426 ALA C CA 1 ATOM 9906 C C . ALA C 2 394 ? 67.737 34.133 10.626 1.00 33.33 ? 426 ALA C C 1 ATOM 9907 O O . ALA C 2 394 ? 66.513 34.169 10.736 1.00 32.55 ? 426 ALA C O 1 ATOM 9908 C CB . ALA C 2 394 ? 69.215 35.057 12.320 1.00 31.74 ? 426 ALA C CB 1 ATOM 9909 N N . PHE C 2 395 ? 68.395 34.387 9.493 1.00 36.89 ? 427 PHE C N 1 ATOM 9910 C CA . PHE C 2 395 ? 67.720 34.819 8.245 1.00 39.56 ? 427 PHE C CA 1 ATOM 9911 C C . PHE C 2 395 ? 66.822 33.759 7.673 1.00 38.57 ? 427 PHE C C 1 ATOM 9912 O O . PHE C 2 395 ? 65.778 34.079 7.095 1.00 39.14 ? 427 PHE C O 1 ATOM 9913 C CB . PHE C 2 395 ? 68.722 35.145 7.124 1.00 40.23 ? 427 PHE C CB 1 ATOM 9914 C CG . PHE C 2 395 ? 69.587 36.324 7.390 1.00 38.81 ? 427 PHE C CG 1 ATOM 9915 C CD1 . PHE C 2 395 ? 69.227 37.288 8.334 1.00 38.28 ? 427 PHE C CD1 1 ATOM 9916 C CD2 . PHE C 2 395 ? 70.756 36.484 6.656 1.00 39.30 ? 427 PHE C CD2 1 ATOM 9917 C CE1 . PHE C 2 395 ? 70.035 38.373 8.554 1.00 40.26 ? 427 PHE C CE1 1 ATOM 9918 C CE2 . PHE C 2 395 ? 71.573 37.570 6.869 1.00 40.33 ? 427 PHE C CE2 1 ATOM 9919 C CZ . PHE C 2 395 ? 71.208 38.519 7.818 1.00 41.91 ? 427 PHE C CZ 1 ATOM 9920 N N . GLN C 2 396 ? 67.312 32.521 7.747 1.00 37.46 ? 428 GLN C N 1 ATOM 9921 C CA . GLN C 2 396 ? 66.556 31.338 7.372 1.00 38.66 ? 428 GLN C CA 1 ATOM 9922 C C . GLN C 2 396 ? 65.319 31.218 8.263 1.00 37.69 ? 428 GLN C C 1 ATOM 9923 O O . GLN C 2 396 ? 64.204 31.011 7.775 1.00 38.06 ? 428 GLN C O 1 ATOM 9924 C CB . GLN C 2 396 ? 67.422 30.073 7.507 1.00 40.04 ? 428 GLN C CB 1 ATOM 9925 C CG . GLN C 2 396 ? 68.311 29.731 6.312 1.00 41.29 ? 428 GLN C CG 1 ATOM 9926 C CD . GLN C 2 396 ? 67.576 29.077 5.137 1.00 43.15 ? 428 GLN C CD 1 ATOM 9927 O OE1 . GLN C 2 396 ? 66.461 28.568 5.268 1.00 44.13 ? 428 GLN C OE1 1 ATOM 9928 N NE2 . GLN C 2 396 ? 68.214 29.094 3.971 1.00 45.46 ? 428 GLN C NE2 1 ATOM 9929 N N . ILE C 2 397 ? 65.527 31.364 9.569 1.00 36.06 ? 429 ILE C N 1 ATOM 9930 C CA . ILE C 2 397 ? 64.454 31.214 10.527 1.00 34.82 ? 429 ILE C CA 1 ATOM 9931 C C . ILE C 2 397 ? 63.366 32.241 10.310 1.00 33.69 ? 429 ILE C C 1 ATOM 9932 O O . ILE C 2 397 ? 62.193 31.860 10.227 1.00 33.66 ? 429 ILE C O 1 ATOM 9933 C CB . ILE C 2 397 ? 64.960 31.309 11.970 1.00 35.23 ? 429 ILE C CB 1 ATOM 9934 C CG1 . ILE C 2 397 ? 65.762 30.060 12.333 1.00 35.04 ? 429 ILE C CG1 1 ATOM 9935 C CG2 . ILE C 2 397 ? 63.796 31.443 12.936 1.00 36.85 ? 429 ILE C CG2 1 ATOM 9936 C CD1 . ILE C 2 397 ? 65.021 28.759 12.146 1.00 33.95 ? 429 ILE C CD1 1 ATOM 9937 N N . CYS C 2 398 ? 63.738 33.519 10.224 1.00 31.34 ? 430 CYS C N 1 ATOM 9938 C CA . CYS C 2 398 ? 62.753 34.573 10.077 1.00 31.22 ? 430 CYS C CA 1 ATOM 9939 C C . CYS C 2 398 ? 61.887 34.402 8.863 1.00 32.62 ? 430 CYS C C 1 ATOM 9940 O O . CYS C 2 398 ? 60.692 34.713 8.904 1.00 31.74 ? 430 CYS C O 1 ATOM 9941 C CB . CYS C 2 398 ? 63.427 35.912 9.972 1.00 32.31 ? 430 CYS C CB 1 ATOM 9942 S SG . CYS C 2 398 ? 63.974 36.430 11.580 1.00 38.85 ? 430 CYS C SG 1 ATOM 9943 N N . ALA C 2 399 ? 62.511 33.923 7.783 1.00 33.34 ? 431 ALA C N 1 ATOM 9944 C CA . ALA C 2 399 ? 61.887 33.784 6.472 1.00 31.96 ? 431 ALA C CA 1 ATOM 9945 C C . ALA C 2 399 ? 60.877 32.667 6.484 1.00 32.16 ? 431 ALA C C 1 ATOM 9946 O O . ALA C 2 399 ? 59.819 32.775 5.876 1.00 34.14 ? 431 ALA C O 1 ATOM 9947 C CB . ALA C 2 399 ? 62.953 33.493 5.436 1.00 32.12 ? 431 ALA C CB 1 ATOM 9948 N N . ILE C 2 400 ? 61.210 31.586 7.176 1.00 32.57 ? 432 ILE C N 1 ATOM 9949 C CA . ILE C 2 400 ? 60.292 30.457 7.303 1.00 34.16 ? 432 ILE C CA 1 ATOM 9950 C C . ILE C 2 400 ? 59.025 30.825 8.080 1.00 33.64 ? 432 ILE C C 1 ATOM 9951 O O . ILE C 2 400 ? 57.955 30.291 7.786 1.00 33.55 ? 432 ILE C O 1 ATOM 9952 C CB . ILE C 2 400 ? 60.948 29.230 7.976 1.00 34.93 ? 432 ILE C CB 1 ATOM 9953 C CG1 . ILE C 2 400 ? 62.194 28.793 7.200 1.00 36.44 ? 432 ILE C CG1 1 ATOM 9954 C CG2 . ILE C 2 400 ? 59.972 28.053 8.036 1.00 34.17 ? 432 ILE C CG2 1 ATOM 9955 C CD1 . ILE C 2 400 ? 63.218 28.134 8.091 1.00 37.68 ? 432 ILE C CD1 1 ATOM 9956 N N . MET C 2 401 ? 59.146 31.725 9.059 1.00 33.22 ? 433 MET C N 1 ATOM 9957 C CA . MET C 2 401 ? 58.027 32.071 9.934 1.00 31.79 ? 433 MET C CA 1 ATOM 9958 C C . MET C 2 401 ? 57.376 33.418 9.640 1.00 30.29 ? 433 MET C C 1 ATOM 9959 O O . MET C 2 401 ? 56.287 33.664 10.109 1.00 31.78 ? 433 MET C O 1 ATOM 9960 C CB . MET C 2 401 ? 58.478 32.004 11.379 1.00 32.42 ? 433 MET C CB 1 ATOM 9961 C CG . MET C 2 401 ? 58.368 30.609 11.935 1.00 35.32 ? 433 MET C CG 1 ATOM 9962 S SD . MET C 2 401 ? 59.596 30.237 13.210 1.00 41.77 ? 433 MET C SD 1 ATOM 9963 C CE . MET C 2 401 ? 58.496 29.299 14.273 1.00 39.20 ? 433 MET C CE 1 ATOM 9964 N N . ASN C 2 402 ? 58.009 34.285 8.863 1.00 28.35 ? 434 ASN C N 1 ATOM 9965 C CA . ASN C 2 402 ? 57.470 35.614 8.647 1.00 27.46 ? 434 ASN C CA 1 ATOM 9966 C C . ASN C 2 402 ? 57.480 36.014 7.176 1.00 29.68 ? 434 ASN C C 1 ATOM 9967 O O . ASN C 2 402 ? 58.517 36.068 6.498 1.00 29.65 ? 434 ASN C O 1 ATOM 9968 C CB . ASN C 2 402 ? 58.230 36.610 9.511 1.00 26.79 ? 434 ASN C CB 1 ATOM 9969 C CG . ASN C 2 402 ? 58.440 36.095 10.929 1.00 26.17 ? 434 ASN C CG 1 ATOM 9970 O OD1 . ASN C 2 402 ? 57.480 35.990 11.715 1.00 25.46 ? 434 ASN C OD1 1 ATOM 9971 N ND2 . ASN C 2 402 ? 59.688 35.731 11.254 1.00 24.94 ? 434 ASN C ND2 1 ATOM 9972 N N . LEU C 2 403 ? 56.291 36.283 6.677 1.00 33.05 ? 435 LEU C N 1 ATOM 9973 C CA . LEU C 2 403 ? 56.096 36.591 5.273 1.00 34.38 ? 435 LEU C CA 1 ATOM 9974 C C . LEU C 2 403 ? 55.725 38.052 4.958 1.00 33.14 ? 435 LEU C C 1 ATOM 9975 O O . LEU C 2 403 ? 55.784 38.434 3.811 1.00 30.20 ? 435 LEU C O 1 ATOM 9976 C CB . LEU C 2 403 ? 55.032 35.642 4.736 1.00 35.81 ? 435 LEU C CB 1 ATOM 9977 C CG . LEU C 2 403 ? 55.576 34.241 4.417 1.00 37.92 ? 435 LEU C CG 1 ATOM 9978 C CD1 . LEU C 2 403 ? 56.161 33.482 5.597 1.00 36.34 ? 435 LEU C CD1 1 ATOM 9979 C CD2 . LEU C 2 403 ? 54.448 33.442 3.781 1.00 40.41 ? 435 LEU C CD2 1 ATOM 9980 N N . ASP C 2 404 ? 55.335 38.847 5.963 1.00 36.21 ? 436 ASP C N 1 ATOM 9981 C CA . ASP C 2 404 ? 54.984 40.266 5.759 1.00 38.42 ? 436 ASP C CA 1 ATOM 9982 C C . ASP C 2 404 ? 56.010 41.146 6.453 1.00 39.90 ? 436 ASP C C 1 ATOM 9983 O O . ASP C 2 404 ? 56.842 40.649 7.197 1.00 39.60 ? 436 ASP C O 1 ATOM 9984 C CB . ASP C 2 404 ? 53.527 40.606 6.181 1.00 38.35 ? 436 ASP C CB 1 ATOM 9985 C CG . ASP C 2 404 ? 53.273 40.465 7.681 1.00 38.60 ? 436 ASP C CG 1 ATOM 9986 O OD1 . ASP C 2 404 ? 53.779 41.296 8.483 1.00 38.14 ? 436 ASP C OD1 1 ATOM 9987 O OD2 . ASP C 2 404 ? 52.521 39.536 8.041 1.00 35.86 -1 436 ASP C OD2 1 ATOM 9988 N N . ASN C 2 405 ? 55.949 42.448 6.196 1.00 42.88 ? 437 ASN C N 1 ATOM 9989 C CA . ASN C 2 405 ? 57.027 43.328 6.563 1.00 44.47 ? 437 ASN C CA 1 ATOM 9990 C C . ASN C 2 405 ? 57.119 43.449 8.033 1.00 44.42 ? 437 ASN C C 1 ATOM 9991 O O . ASN C 2 405 ? 58.206 43.398 8.599 1.00 46.06 ? 437 ASN C O 1 ATOM 9992 C CB . ASN C 2 405 ? 56.837 44.725 6.014 1.00 47.35 ? 437 ASN C CB 1 ATOM 9993 C CG . ASN C 2 405 ? 57.948 45.660 6.461 1.00 51.05 ? 437 ASN C CG 1 ATOM 9994 O OD1 . ASN C 2 405 ? 59.002 45.762 5.819 1.00 57.24 ? 437 ASN C OD1 1 ATOM 9995 N ND2 . ASN C 2 405 ? 57.747 46.305 7.591 1.00 51.14 ? 437 ASN C ND2 1 ATOM 9996 N N . ILE C 2 406 ? 55.969 43.648 8.652 1.00 44.81 ? 438 ILE C N 1 ATOM 9997 C CA . ILE C 2 406 ? 55.931 43.844 10.095 1.00 48.55 ? 438 ILE C CA 1 ATOM 9998 C C . ILE C 2 406 ? 56.585 42.670 10.843 1.00 44.72 ? 438 ILE C C 1 ATOM 9999 O O . ILE C 2 406 ? 57.549 42.869 11.586 1.00 41.46 ? 438 ILE C O 1 ATOM 10000 C CB . ILE C 2 406 ? 54.479 44.192 10.583 1.00 53.42 ? 438 ILE C CB 1 ATOM 10001 C CG1 . ILE C 2 406 ? 54.353 45.711 10.766 1.00 55.08 ? 438 ILE C CG1 1 ATOM 10002 C CG2 . ILE C 2 406 ? 54.061 43.477 11.877 1.00 53.91 ? 438 ILE C CG2 1 ATOM 10003 C CD1 . ILE C 2 406 ? 55.259 46.320 11.833 1.00 57.23 ? 438 ILE C CD1 1 ATOM 10004 N N . SER C 2 407 ? 56.081 41.458 10.610 1.00 41.57 ? 439 SER C N 1 ATOM 10005 C CA . SER C 2 407 ? 56.551 40.254 11.315 1.00 39.67 ? 439 SER C CA 1 ATOM 10006 C C . SER C 2 407 ? 58.037 39.839 11.022 1.00 37.99 ? 439 SER C C 1 ATOM 10007 O O . SER C 2 407 ? 58.701 39.261 11.903 1.00 35.50 ? 439 SER C O 1 ATOM 10008 C CB . SER C 2 407 ? 55.565 39.091 11.074 1.00 38.82 ? 439 SER C CB 1 ATOM 10009 O OG . SER C 2 407 ? 55.039 39.097 9.741 1.00 39.16 ? 439 SER C OG 1 ATOM 10010 N N . TYR C 2 408 ? 58.544 40.157 9.818 1.00 35.32 ? 440 TYR C N 1 ATOM 10011 C CA . TYR C 2 408 ? 59.914 39.832 9.417 1.00 33.74 ? 440 TYR C CA 1 ATOM 10012 C C . TYR C 2 408 ? 60.967 40.700 10.040 1.00 37.86 ? 440 TYR C C 1 ATOM 10013 O O . TYR C 2 408 ? 62.135 40.307 10.092 1.00 41.31 ? 440 TYR C O 1 ATOM 10014 C CB . TYR C 2 408 ? 60.117 40.006 7.940 1.00 32.05 ? 440 TYR C CB 1 ATOM 10015 C CG . TYR C 2 408 ? 61.470 39.524 7.548 1.00 30.80 ? 440 TYR C CG 1 ATOM 10016 C CD1 . TYR C 2 408 ? 61.682 38.181 7.357 1.00 30.94 ? 440 TYR C CD1 1 ATOM 10017 C CD2 . TYR C 2 408 ? 62.546 40.392 7.416 1.00 30.69 ? 440 TYR C CD2 1 ATOM 10018 C CE1 . TYR C 2 408 ? 62.913 37.684 7.008 1.00 31.94 ? 440 TYR C CE1 1 ATOM 10019 C CE2 . TYR C 2 408 ? 63.808 39.912 7.072 1.00 31.92 ? 440 TYR C CE2 1 ATOM 10020 C CZ . TYR C 2 408 ? 63.986 38.535 6.865 1.00 33.86 ? 440 TYR C CZ 1 ATOM 10021 O OH . TYR C 2 408 ? 65.200 37.926 6.505 1.00 35.06 ? 440 TYR C OH 1 ATOM 10022 N N . ALA C 2 409 ? 60.581 41.909 10.435 1.00 41.56 ? 441 ALA C N 1 ATOM 10023 C CA . ALA C 2 409 ? 61.468 42.797 11.192 1.00 43.70 ? 441 ALA C CA 1 ATOM 10024 C C . ALA C 2 409 ? 61.463 42.428 12.684 1.00 44.50 ? 441 ALA C C 1 ATOM 10025 O O . ALA C 2 409 ? 62.529 42.237 13.270 1.00 42.96 ? 441 ALA C O 1 ATOM 10026 C CB . ALA C 2 409 ? 61.056 44.248 10.990 1.00 44.92 ? 441 ALA C CB 1 ATOM 10027 N N . ASP C 2 410 ? 60.257 42.322 13.263 1.00 45.60 ? 442 ASP C N 1 ATOM 10028 C CA . ASP C 2 410 ? 60.029 41.864 14.647 1.00 47.52 ? 442 ASP C CA 1 ATOM 10029 C C . ASP C 2 410 ? 60.939 40.667 14.928 1.00 46.28 ? 442 ASP C C 1 ATOM 10030 O O . ASP C 2 410 ? 61.468 40.507 16.037 1.00 43.66 ? 442 ASP C O 1 ATOM 10031 C CB . ASP C 2 410 ? 58.529 41.466 14.867 1.00 51.38 ? 442 ASP C CB 1 ATOM 10032 C CG . ASP C 2 410 ? 58.000 41.752 16.323 1.00 55.36 ? 442 ASP C CG 1 ATOM 10033 O OD1 . ASP C 2 410 ? 57.059 42.585 16.463 1.00 52.94 ? 442 ASP C OD1 1 ATOM 10034 O OD2 . ASP C 2 410 ? 58.502 41.142 17.312 1.00 55.37 -1 442 ASP C OD2 1 ATOM 10035 N N . CYS C 2 411 ? 61.114 39.827 13.911 1.00 45.48 ? 443 CYS C N 1 ATOM 10036 C CA . CYS C 2 411 ? 61.914 38.608 14.036 1.00 45.09 ? 443 CYS C CA 1 ATOM 10037 C C . CYS C 2 411 ? 63.411 38.925 14.141 1.00 46.49 ? 443 CYS C C 1 ATOM 10038 O O . CYS C 2 411 ? 64.123 38.371 14.996 1.00 43.74 ? 443 CYS C O 1 ATOM 10039 C CB . CYS C 2 411 ? 61.593 37.705 12.858 1.00 43.94 ? 443 CYS C CB 1 ATOM 10040 S SG . CYS C 2 411 ? 62.389 36.095 12.828 1.00 43.64 ? 443 CYS C SG 1 ATOM 10041 N N . LEU C 2 412 ? 63.813 39.985 13.473 1.00 49.57 ? 444 LEU C N 1 ATOM 10042 C CA . LEU C 2 412 ? 65.149 40.496 13.566 1.00 51.68 ? 444 LEU C CA 1 ATOM 10043 C C . LEU C 2 412 ? 65.251 41.419 14.771 1.00 57.11 ? 444 LEU C C 1 ATOM 10044 O O . LEU C 2 412 ? 65.677 42.544 14.662 1.00 54.03 ? 444 LEU C O 1 ATOM 10045 C CB . LEU C 2 412 ? 65.464 41.240 12.303 1.00 51.00 ? 444 LEU C CB 1 ATOM 10046 C CG . LEU C 2 412 ? 65.491 40.286 11.125 1.00 49.80 ? 444 LEU C CG 1 ATOM 10047 C CD1 . LEU C 2 412 ? 65.803 41.014 9.849 1.00 48.45 ? 444 LEU C CD1 1 ATOM 10048 C CD2 . LEU C 2 412 ? 66.586 39.300 11.407 1.00 50.26 ? 444 LEU C CD2 1 ATOM 10049 N N . LYS C 2 413 ? 64.818 40.892 15.917 1.00 66.16 ? 445 LYS C N 1 ATOM 10050 C CA . LYS C 2 413 ? 64.837 41.483 17.253 1.00 65.66 ? 445 LYS C CA 1 ATOM 10051 C C . LYS C 2 413 ? 65.752 40.503 17.906 1.00 66.92 ? 445 LYS C C 1 ATOM 10052 O O . LYS C 2 413 ? 65.536 40.007 18.993 1.00 61.32 ? 445 LYS C O 1 ATOM 10053 C CB . LYS C 2 413 ? 63.464 41.457 17.884 1.00 71.16 ? 445 LYS C CB 1 ATOM 10054 C CG . LYS C 2 413 ? 63.429 41.489 19.416 1.00 72.94 ? 445 LYS C CG 1 ATOM 10055 C CD . LYS C 2 413 ? 62.568 42.615 20.002 1.00 71.64 ? 445 LYS C CD 1 ATOM 10056 C CE . LYS C 2 413 ? 61.086 42.505 19.695 1.00 68.50 ? 445 LYS C CE 1 ATOM 10057 N NZ . LYS C 2 413 ? 60.554 41.182 20.088 1.00 67.43 1 445 LYS C NZ 1 ATOM 10058 N N . GLN C 2 414 ? 66.777 40.196 17.137 1.00 70.14 ? 446 GLN C N 1 ATOM 10059 C CA . GLN C 2 414 ? 67.846 39.233 17.441 1.00 65.45 ? 446 GLN C CA 1 ATOM 10060 C C . GLN C 2 414 ? 69.134 39.913 16.920 1.00 65.03 ? 446 GLN C C 1 ATOM 10061 O O . GLN C 2 414 ? 70.045 40.210 17.695 1.00 59.24 ? 446 GLN C O 1 ATOM 10062 C CB . GLN C 2 414 ? 67.533 37.927 16.717 1.00 61.94 ? 446 GLN C CB 1 ATOM 10063 C CG . GLN C 2 414 ? 68.708 36.962 16.697 1.00 64.21 ? 446 GLN C CG 1 ATOM 10064 C CD . GLN C 2 414 ? 68.280 35.503 16.756 1.00 66.41 ? 446 GLN C CD 1 ATOM 10065 O OE1 . GLN C 2 414 ? 67.330 35.109 16.086 1.00 66.23 ? 446 GLN C OE1 1 ATOM 10066 N NE2 . GLN C 2 414 ? 68.981 34.694 17.566 1.00 65.48 ? 446 GLN C NE2 1 ATOM 10067 N N . LEU C 2 415 ? 69.167 40.191 15.612 1.00 65.24 ? 447 LEU C N 1 ATOM 10068 C CA . LEU C 2 415 ? 70.236 40.980 15.006 1.00 60.23 ? 447 LEU C CA 1 ATOM 10069 C C . LEU C 2 415 ? 70.168 42.447 15.443 1.00 56.99 ? 447 LEU C C 1 ATOM 10070 O O . LEU C 2 415 ? 70.975 42.875 16.252 1.00 56.03 ? 447 LEU C O 1 ATOM 10071 C CB . LEU C 2 415 ? 70.171 40.924 13.477 1.00 55.77 ? 447 LEU C CB 1 ATOM 10072 C CG . LEU C 2 415 ? 70.698 39.605 12.923 1.00 54.31 ? 447 LEU C CG 1 ATOM 10073 C CD1 . LEU C 2 415 ? 69.651 38.493 12.982 1.00 51.13 ? 447 LEU C CD1 1 ATOM 10074 C CD2 . LEU C 2 415 ? 71.207 39.858 11.512 1.00 54.45 ? 447 LEU C CD2 1 HETATM 10075 C C1 . NAG D 3 . ? 5.864 22.321 -15.809 1.00 26.64 ? 601 NAG A C1 1 HETATM 10076 C C2 . NAG D 3 . ? 4.301 22.427 -15.637 1.00 27.24 ? 601 NAG A C2 1 HETATM 10077 C C3 . NAG D 3 . ? 3.644 23.679 -16.195 1.00 27.24 ? 601 NAG A C3 1 HETATM 10078 C C4 . NAG D 3 . ? 4.370 24.944 -15.727 1.00 28.55 ? 601 NAG A C4 1 HETATM 10079 C C5 . NAG D 3 . ? 5.817 24.853 -16.278 1.00 28.43 ? 601 NAG A C5 1 HETATM 10080 C C6 . NAG D 3 . ? 6.695 26.009 -15.840 1.00 28.96 ? 601 NAG A C6 1 HETATM 10081 C C7 . NAG D 3 . ? 3.506 20.098 -15.415 1.00 28.40 ? 601 NAG A C7 1 HETATM 10082 C C8 . NAG D 3 . ? 2.835 18.879 -16.092 1.00 28.56 ? 601 NAG A C8 1 HETATM 10083 N N2 . NAG D 3 . ? 3.663 21.212 -16.195 1.00 27.16 ? 601 NAG A N2 1 HETATM 10084 O O3 . NAG D 3 . ? 2.353 23.686 -15.624 1.00 26.62 ? 601 NAG A O3 1 HETATM 10085 O O4 . NAG D 3 . ? 3.625 26.220 -16.103 1.00 30.60 ? 601 NAG A O4 1 HETATM 10086 O O5 . NAG D 3 . ? 6.510 23.676 -15.766 1.00 27.91 ? 601 NAG A O5 1 HETATM 10087 O O6 . NAG D 3 . ? 6.624 26.013 -14.405 1.00 29.37 ? 601 NAG A O6 1 HETATM 10088 O O7 . NAG D 3 . ? 3.882 20.002 -14.234 1.00 27.97 ? 601 NAG A O7 1 HETATM 10089 C C1 . NAG E 3 . ? 25.468 3.991 -24.534 1.00 36.03 ? 602 NAG A C1 1 HETATM 10090 C C2 . NAG E 3 . ? 26.459 4.482 -25.609 1.00 35.82 ? 602 NAG A C2 1 HETATM 10091 C C3 . NAG E 3 . ? 26.748 5.955 -25.402 1.00 36.49 ? 602 NAG A C3 1 HETATM 10092 C C4 . NAG E 3 . ? 25.510 6.798 -25.633 1.00 36.88 ? 602 NAG A C4 1 HETATM 10093 C C5 . NAG E 3 . ? 24.475 6.415 -24.520 1.00 37.69 ? 602 NAG A C5 1 HETATM 10094 C C6 . NAG E 3 . ? 23.170 7.237 -24.674 1.00 37.70 ? 602 NAG A C6 1 HETATM 10095 C C7 . NAG E 3 . ? 27.810 2.424 -25.861 1.00 40.46 ? 602 NAG A C7 1 HETATM 10096 C C8 . NAG E 3 . ? 29.170 1.735 -25.641 1.00 39.65 ? 602 NAG A C8 1 HETATM 10097 N N2 . NAG E 3 . ? 27.715 3.724 -25.475 1.00 37.83 ? 602 NAG A N2 1 HETATM 10098 O O3 . NAG E 3 . ? 27.766 6.404 -26.296 1.00 37.28 ? 602 NAG A O3 1 HETATM 10099 O O4 . NAG E 3 . ? 25.900 8.238 -25.606 1.00 36.54 ? 602 NAG A O4 1 HETATM 10100 O O5 . NAG E 3 . ? 24.282 4.938 -24.478 1.00 37.62 ? 602 NAG A O5 1 HETATM 10101 O O6 . NAG E 3 . ? 22.083 6.317 -24.902 1.00 37.80 ? 602 NAG A O6 1 HETATM 10102 O O7 . NAG E 3 . ? 26.863 1.781 -26.322 1.00 40.75 ? 602 NAG A O7 1 HETATM 10103 C C1 . NAG F 3 . ? 1.628 -10.650 7.608 1.00 49.23 ? 603 NAG A C1 1 HETATM 10104 C C2 . NAG F 3 . ? 0.363 -11.080 8.341 1.00 52.62 ? 603 NAG A C2 1 HETATM 10105 C C3 . NAG F 3 . ? 0.034 -12.546 7.939 1.00 56.30 ? 603 NAG A C3 1 HETATM 10106 C C4 . NAG F 3 . ? -0.327 -12.550 6.452 1.00 57.86 ? 603 NAG A C4 1 HETATM 10107 C C5 . NAG F 3 . ? 0.907 -12.161 5.667 1.00 55.16 ? 603 NAG A C5 1 HETATM 10108 C C6 . NAG F 3 . ? 0.485 -11.864 4.245 1.00 54.21 ? 603 NAG A C6 1 HETATM 10109 C C7 . NAG F 3 . ? 0.116 -9.868 10.471 1.00 48.69 ? 603 NAG A C7 1 HETATM 10110 C C8 . NAG F 3 . ? 0.715 -9.625 11.874 1.00 47.77 ? 603 NAG A C8 1 HETATM 10111 N N2 . NAG F 3 . ? 0.715 -10.834 9.751 1.00 51.82 ? 603 NAG A N2 1 HETATM 10112 O O3 . NAG F 3 . ? -1.101 -13.044 8.633 1.00 61.51 ? 603 NAG A O3 1 HETATM 10113 O O4 . NAG F 3 . ? -0.893 -13.829 5.997 1.00 56.31 ? 603 NAG A O4 1 HETATM 10114 O O5 . NAG F 3 . ? 1.428 -10.894 6.166 1.00 55.17 ? 603 NAG A O5 1 HETATM 10115 O O6 . NAG F 3 . ? 1.502 -12.466 3.448 1.00 51.71 ? 603 NAG A O6 1 HETATM 10116 O O7 . NAG F 3 . ? -0.837 -9.210 10.056 1.00 45.33 ? 603 NAG A O7 1 HETATM 10117 C C1 . NAG G 3 . ? 24.734 18.335 -0.267 1.00 31.66 ? 604 NAG A C1 1 HETATM 10118 C C2 . NAG G 3 . ? 24.944 18.616 1.330 1.00 33.33 ? 604 NAG A C2 1 HETATM 10119 C C3 . NAG G 3 . ? 23.993 19.633 2.020 1.00 34.54 ? 604 NAG A C3 1 HETATM 10120 C C4 . NAG G 3 . ? 24.125 20.987 1.359 1.00 37.85 ? 604 NAG A C4 1 HETATM 10121 C C5 . NAG G 3 . ? 23.743 20.771 -0.123 1.00 38.48 ? 604 NAG A C5 1 HETATM 10122 C C6 . NAG G 3 . ? 23.971 22.085 -0.845 1.00 39.30 ? 604 NAG A C6 1 HETATM 10123 C C7 . NAG G 3 . ? 25.945 16.541 2.157 1.00 33.44 ? 604 NAG A C7 1 HETATM 10124 C C8 . NAG G 3 . ? 25.792 15.326 3.052 1.00 33.80 ? 604 NAG A C8 1 HETATM 10125 N N2 . NAG G 3 . ? 24.904 17.388 2.132 1.00 32.84 ? 604 NAG A N2 1 HETATM 10126 O O4 . NAG G 3 . ? 23.260 22.066 1.986 1.00 37.96 ? 604 NAG A O4 1 HETATM 10127 O O5 . NAG G 3 . ? 24.489 19.651 -0.881 1.00 34.43 ? 604 NAG A O5 1 HETATM 10128 O O6 . NAG G 3 . ? 25.132 21.726 -1.625 1.00 42.68 ? 604 NAG A O6 1 HETATM 10129 O O7 . NAG G 3 . ? 26.960 16.670 1.477 1.00 36.62 ? 604 NAG A O7 1 HETATM 10130 ZN ZN . ZN H 4 . ? 14.467 -4.096 -8.727 1.00 27.67 ? 605 ZN A ZN 1 HETATM 10131 ZN ZN . ZN I 4 . ? 15.944 -0.895 -9.188 1.00 14.20 ? 606 ZN A ZN 1 HETATM 10132 O O3P . C5P J 5 . ? 11.837 -0.701 -9.316 1.00 52.29 ? 607 C5P A O3P 1 HETATM 10133 P P . C5P J 5 . ? 12.931 -1.661 -8.895 1.00 50.37 ? 607 C5P A P 1 HETATM 10134 O O1P . C5P J 5 . ? 12.930 -3.023 -9.521 1.00 51.04 -1 607 C5P A O1P 1 HETATM 10135 O O2P . C5P J 5 . ? 14.312 -1.090 -8.699 1.00 48.14 ? 607 C5P A O2P 1 HETATM 10136 O "O5'" . C5P J 5 . ? 12.445 -1.999 -7.425 1.00 62.02 ? 607 C5P A "O5'" 1 HETATM 10137 C "C5'" . C5P J 5 . ? 12.737 -1.019 -6.441 1.00 72.49 ? 607 C5P A "C5'" 1 HETATM 10138 C "C4'" . C5P J 5 . ? 11.911 -1.188 -5.168 1.00 77.08 ? 607 C5P A "C4'" 1 HETATM 10139 O "O4'" . C5P J 5 . ? 12.230 -0.096 -4.294 1.00 80.79 ? 607 C5P A "O4'" 1 HETATM 10140 C "C3'" . C5P J 5 . ? 10.407 -1.179 -5.435 1.00 76.77 ? 607 C5P A "C3'" 1 HETATM 10141 O "O3'" . C5P J 5 . ? 9.733 -2.233 -4.728 1.00 68.04 ? 607 C5P A "O3'" 1 HETATM 10142 C "C2'" . C5P J 5 . ? 9.953 0.189 -4.970 1.00 79.58 ? 607 C5P A "C2'" 1 HETATM 10143 O "O2'" . C5P J 5 . ? 8.837 0.045 -4.087 1.00 76.48 ? 607 C5P A "O2'" 1 HETATM 10144 C "C1'" . C5P J 5 . ? 11.152 0.838 -4.270 1.00 82.42 ? 607 C5P A "C1'" 1 HETATM 10145 N N1 . C5P J 5 . ? 11.605 2.122 -4.864 1.00 84.06 ? 607 C5P A N1 1 HETATM 10146 C C2 . C5P J 5 . ? 11.532 3.272 -4.032 1.00 84.81 ? 607 C5P A C2 1 HETATM 10147 N N3 . C5P J 5 . ? 11.925 4.465 -4.507 1.00 83.63 ? 607 C5P A N3 1 HETATM 10148 C C4 . C5P J 5 . ? 12.394 4.570 -5.762 1.00 81.89 ? 607 C5P A C4 1 HETATM 10149 C C5 . C5P J 5 . ? 12.481 3.471 -6.618 1.00 77.34 ? 607 C5P A C5 1 HETATM 10150 C C6 . C5P J 5 . ? 12.080 2.238 -6.132 1.00 77.16 ? 607 C5P A C6 1 HETATM 10151 O O2 . C5P J 5 . ? 11.093 3.202 -2.856 1.00 82.75 ? 607 C5P A O2 1 HETATM 10152 N N4 . C5P J 5 . ? 12.780 5.787 -6.156 1.00 80.30 ? 607 C5P A N4 1 HETATM 10153 C C1 . NAG K 3 . ? 51.490 -48.887 -12.756 1.00 42.53 ? 601 NAG B C1 1 HETATM 10154 C C2 . NAG K 3 . ? 52.192 -50.277 -12.598 1.00 43.66 ? 601 NAG B C2 1 HETATM 10155 C C3 . NAG K 3 . ? 51.420 -51.529 -13.050 1.00 42.67 ? 601 NAG B C3 1 HETATM 10156 C C4 . NAG K 3 . ? 49.977 -51.430 -12.627 1.00 42.49 ? 601 NAG B C4 1 HETATM 10157 C C5 . NAG K 3 . ? 49.386 -50.238 -13.390 1.00 43.67 ? 601 NAG B C5 1 HETATM 10158 C C6 . NAG K 3 . ? 47.935 -50.056 -13.024 1.00 45.90 ? 601 NAG B C6 1 HETATM 10159 C C7 . NAG K 3 . ? 54.556 -49.709 -12.703 1.00 46.07 ? 601 NAG B C7 1 HETATM 10160 C C8 . NAG K 3 . ? 55.834 -49.644 -13.544 1.00 46.04 ? 601 NAG B C8 1 HETATM 10161 N N2 . NAG K 3 . ? 53.461 -50.183 -13.333 1.00 44.53 ? 601 NAG B N2 1 HETATM 10162 O O3 . NAG K 3 . ? 52.007 -52.677 -12.381 1.00 41.05 ? 601 NAG B O3 1 HETATM 10163 O O4 . NAG K 3 . ? 49.262 -52.693 -12.881 1.00 38.88 ? 601 NAG B O4 1 HETATM 10164 O O5 . NAG K 3 . ? 50.033 -48.982 -13.047 1.00 44.24 ? 601 NAG B O5 1 HETATM 10165 O O6 . NAG K 3 . ? 47.922 -50.148 -11.593 1.00 46.49 ? 601 NAG B O6 1 HETATM 10166 O O7 . NAG K 3 . ? 54.559 -49.328 -11.529 1.00 44.92 ? 601 NAG B O7 1 HETATM 10167 C C1 . NAG L 3 . ? 57.793 -22.500 -21.994 1.00 51.38 ? 602 NAG B C1 1 HETATM 10168 C C2 . NAG L 3 . ? 56.917 -23.765 -21.571 1.00 55.47 ? 602 NAG B C2 1 HETATM 10169 C C3 . NAG L 3 . ? 55.591 -23.775 -22.323 1.00 56.72 ? 602 NAG B C3 1 HETATM 10170 C C4 . NAG L 3 . ? 54.852 -22.442 -22.266 1.00 56.57 ? 602 NAG B C4 1 HETATM 10171 C C5 . NAG L 3 . ? 55.772 -21.284 -22.671 1.00 52.90 ? 602 NAG B C5 1 HETATM 10172 C C6 . NAG L 3 . ? 55.154 -19.916 -22.375 1.00 57.86 ? 602 NAG B C6 1 HETATM 10173 C C7 . NAG L 3 . ? 57.374 -26.318 -21.571 1.00 68.64 ? 602 NAG B C7 1 HETATM 10174 C C8 . NAG L 3 . ? 56.301 -26.593 -20.522 1.00 70.21 ? 602 NAG B C8 1 HETATM 10175 N N2 . NAG L 3 . ? 57.619 -25.026 -21.958 1.00 62.97 ? 602 NAG B N2 1 HETATM 10176 O O3 . NAG L 3 . ? 54.733 -24.783 -21.767 1.00 58.13 ? 602 NAG B O3 1 HETATM 10177 O O4 . NAG L 3 . ? 53.655 -22.513 -23.141 1.00 59.84 ? 602 NAG B O4 1 HETATM 10178 O O5 . NAG L 3 . ? 56.970 -21.309 -21.922 1.00 46.24 ? 602 NAG B O5 1 HETATM 10179 O O6 . NAG L 3 . ? 53.825 -20.079 -21.804 1.00 60.08 ? 602 NAG B O6 1 HETATM 10180 O O7 . NAG L 3 . ? 58.022 -27.275 -22.003 1.00 74.62 ? 602 NAG B O7 1 HETATM 10181 C C1 . NAG M 3 . ? 52.888 -23.560 -23.507 1.00 70.29 ? 603 NAG B C1 1 HETATM 10182 C C2 . NAG M 3 . ? 52.827 -25.003 -24.006 1.00 72.55 ? 603 NAG B C2 1 HETATM 10183 C C3 . NAG M 3 . ? 51.493 -25.178 -24.724 1.00 71.45 ? 603 NAG B C3 1 HETATM 10184 C C4 . NAG M 3 . ? 50.500 -25.413 -23.592 1.00 68.96 ? 603 NAG B C4 1 HETATM 10185 C C5 . NAG M 3 . ? 50.588 -24.263 -22.516 1.00 69.29 ? 603 NAG B C5 1 HETATM 10186 C C6 . NAG M 3 . ? 50.327 -24.860 -21.152 1.00 66.54 ? 603 NAG B C6 1 HETATM 10187 C C7 . NAG M 3 . ? 54.438 -26.674 -24.792 1.00 78.56 ? 603 NAG B C7 1 HETATM 10188 C C8 . NAG M 3 . ? 53.728 -27.682 -23.828 1.00 77.33 ? 603 NAG B C8 1 HETATM 10189 N N2 . NAG M 3 . ? 53.963 -25.410 -24.847 1.00 73.26 ? 603 NAG B N2 1 HETATM 10190 O O3 . NAG M 3 . ? 51.507 -26.266 -25.694 1.00 67.42 ? 603 NAG B O3 1 HETATM 10191 O O4 . NAG M 3 . ? 49.160 -25.481 -24.101 1.00 67.56 ? 603 NAG B O4 1 HETATM 10192 O O5 . NAG M 3 . ? 51.885 -23.482 -22.428 1.00 70.58 ? 603 NAG B O5 1 HETATM 10193 O O6 . NAG M 3 . ? 51.585 -24.667 -20.519 1.00 62.85 ? 603 NAG B O6 1 HETATM 10194 O O7 . NAG M 3 . ? 55.381 -27.043 -25.485 1.00 78.73 ? 603 NAG B O7 1 HETATM 10195 C C1 . NAG N 3 . ? 82.084 -36.070 11.082 1.00 73.84 ? 604 NAG B C1 1 HETATM 10196 C C2 . NAG N 3 . ? 83.272 -37.031 11.420 1.00 77.14 ? 604 NAG B C2 1 HETATM 10197 C C3 . NAG N 3 . ? 84.589 -36.405 10.877 1.00 79.53 ? 604 NAG B C3 1 HETATM 10198 C C4 . NAG N 3 . ? 84.496 -36.237 9.366 1.00 78.87 ? 604 NAG B C4 1 HETATM 10199 C C5 . NAG N 3 . ? 83.358 -35.232 9.119 1.00 77.51 ? 604 NAG B C5 1 HETATM 10200 C C6 . NAG N 3 . ? 83.048 -34.872 7.661 1.00 76.23 ? 604 NAG B C6 1 HETATM 10201 C C7 . NAG N 3 . ? 82.697 -38.245 13.533 1.00 75.19 ? 604 NAG B C7 1 HETATM 10202 C C8 . NAG N 3 . ? 82.917 -38.282 15.057 1.00 72.10 ? 604 NAG B C8 1 HETATM 10203 N N2 . NAG N 3 . ? 83.357 -37.252 12.885 1.00 76.28 ? 604 NAG B N2 1 HETATM 10204 O O3 . NAG N 3 . ? 85.736 -37.212 11.176 1.00 85.35 ? 604 NAG B O3 1 HETATM 10205 O O4 . NAG N 3 . ? 85.777 -35.797 8.852 1.00 78.84 ? 604 NAG B O4 1 HETATM 10206 O O5 . NAG N 3 . ? 82.134 -35.814 9.642 1.00 76.07 ? 604 NAG B O5 1 HETATM 10207 O O6 . NAG N 3 . ? 83.900 -35.626 6.805 1.00 75.87 ? 604 NAG B O6 1 HETATM 10208 O O7 . NAG N 3 . ? 81.979 -39.087 12.984 1.00 75.54 ? 604 NAG B O7 1 HETATM 10209 C C1 . NAG O 3 . ? 45.323 -30.600 2.393 1.00 45.34 ? 605 NAG B C1 1 HETATM 10210 C C2 . NAG O 3 . ? 45.295 -30.481 3.984 1.00 44.69 ? 605 NAG B C2 1 HETATM 10211 C C3 . NAG O 3 . ? 45.008 -31.786 4.705 1.00 47.52 ? 605 NAG B C3 1 HETATM 10212 C C4 . NAG O 3 . ? 43.646 -32.421 4.264 1.00 51.02 ? 605 NAG B C4 1 HETATM 10213 C C5 . NAG O 3 . ? 43.668 -32.618 2.701 1.00 51.92 ? 605 NAG B C5 1 HETATM 10214 C C6 . NAG O 3 . ? 42.323 -33.199 2.296 1.00 52.55 ? 605 NAG B C6 1 HETATM 10215 C C7 . NAG O 3 . ? 46.610 -28.827 5.247 1.00 44.99 ? 605 NAG B C7 1 HETATM 10216 C C8 . NAG O 3 . ? 47.997 -28.416 5.741 1.00 47.33 ? 605 NAG B C8 1 HETATM 10217 N N2 . NAG O 3 . ? 46.560 -29.965 4.536 1.00 42.14 ? 605 NAG B N2 1 HETATM 10218 O O3 . NAG O 3 . ? 44.975 -31.428 6.092 1.00 51.15 ? 605 NAG B O3 1 HETATM 10219 O O4 . NAG O 3 . ? 43.277 -33.708 5.007 1.00 45.40 ? 605 NAG B O4 1 HETATM 10220 O O5 . NAG O 3 . ? 44.039 -31.354 1.940 1.00 48.85 ? 605 NAG B O5 1 HETATM 10221 O O6 . NAG O 3 . ? 42.347 -34.550 2.827 1.00 52.74 ? 605 NAG B O6 1 HETATM 10222 O O7 . NAG O 3 . ? 45.642 -28.117 5.498 1.00 46.01 ? 605 NAG B O7 1 HETATM 10223 ZN ZN . ZN P 4 . ? 66.591 -28.266 -6.113 1.00 35.79 ? 606 ZN B ZN 1 HETATM 10224 ZN ZN . ZN Q 4 . ? 70.098 -28.074 -5.801 1.00 40.09 ? 607 ZN B ZN 1 HETATM 10225 C C1 . GOL R 6 . ? 77.351 -43.571 17.245 1.00 43.77 ? 608 GOL B C1 1 HETATM 10226 O O1 . GOL R 6 . ? 77.576 -44.937 16.896 1.00 41.66 ? 608 GOL B O1 1 HETATM 10227 C C2 . GOL R 6 . ? 78.441 -43.090 18.218 1.00 44.70 ? 608 GOL B C2 1 HETATM 10228 O O2 . GOL R 6 . ? 78.704 -41.701 17.912 1.00 42.76 ? 608 GOL B O2 1 HETATM 10229 C C3 . GOL R 6 . ? 77.956 -43.344 19.663 1.00 44.56 ? 608 GOL B C3 1 HETATM 10230 O O3 . GOL R 6 . ? 79.073 -43.113 20.560 1.00 41.81 ? 608 GOL B O3 1 HETATM 10231 C C1 . GOL S 6 . ? 81.822 -9.047 -23.332 1.00 68.70 ? 609 GOL B C1 1 HETATM 10232 O O1 . GOL S 6 . ? 82.191 -10.382 -23.708 1.00 67.93 ? 609 GOL B O1 1 HETATM 10233 C C2 . GOL S 6 . ? 80.722 -8.437 -24.264 1.00 66.03 ? 609 GOL B C2 1 HETATM 10234 O O2 . GOL S 6 . ? 79.802 -9.428 -24.767 1.00 63.32 ? 609 GOL B O2 1 HETATM 10235 C C3 . GOL S 6 . ? 79.973 -7.302 -23.529 1.00 62.35 ? 609 GOL B C3 1 HETATM 10236 O O3 . GOL S 6 . ? 78.998 -7.831 -22.591 1.00 52.29 ? 609 GOL B O3 1 HETATM 10237 C C1 . MLI T 7 . ? 79.430 -20.391 -26.567 1.00 64.11 ? 610 MLI B C1 1 HETATM 10238 C C2 . MLI T 7 . ? 78.230 -19.631 -27.281 1.00 65.44 ? 610 MLI B C2 1 HETATM 10239 C C3 . MLI T 7 . ? 79.986 -19.804 -25.204 1.00 62.28 ? 610 MLI B C3 1 HETATM 10240 O O6 . MLI T 7 . ? 77.232 -20.313 -27.627 1.00 67.74 ? 610 MLI B O6 1 HETATM 10241 O O7 . MLI T 7 . ? 78.349 -18.414 -27.564 1.00 63.98 ? 610 MLI B O7 1 HETATM 10242 O O8 . MLI T 7 . ? 79.739 -18.606 -24.923 1.00 65.24 ? 610 MLI B O8 1 HETATM 10243 O O9 . MLI T 7 . ? 80.698 -20.558 -24.476 1.00 52.60 ? 610 MLI B O9 1 HETATM 10244 C "C1'" . RP5 U 8 . ? 69.765 -33.350 -0.637 1.00 66.25 ? 611 RP5 B "C1'" 1 HETATM 10245 O "O1'" . RP5 U 8 . ? 69.850 -32.824 -1.932 1.00 68.52 ? 611 RP5 B "O1'" 1 HETATM 10246 C "C2'" . RP5 U 8 . ? 68.300 -33.672 -0.446 1.00 67.36 ? 611 RP5 B "C2'" 1 HETATM 10247 O "O2'" . RP5 U 8 . ? 68.039 -35.007 -0.854 1.00 62.59 ? 611 RP5 B "O2'" 1 HETATM 10248 C "C3'" . RP5 U 8 . ? 67.568 -32.719 -1.356 1.00 68.15 ? 611 RP5 B "C3'" 1 HETATM 10249 O "O3'" . RP5 U 8 . ? 66.297 -33.207 -1.789 1.00 61.54 ? 611 RP5 B "O3'" 1 HETATM 10250 C "C4'" . RP5 U 8 . ? 68.543 -32.664 -2.473 1.00 70.20 ? 611 RP5 B "C4'" 1 HETATM 10251 C "C5'" . RP5 U 8 . ? 68.439 -31.381 -3.237 1.00 73.23 ? 611 RP5 B "C5'" 1 HETATM 10252 O "O5'" . RP5 U 8 . ? 69.057 -31.738 -4.450 1.00 76.83 ? 611 RP5 B "O5'" 1 HETATM 10253 P "P'" . RP5 U 8 . ? 68.803 -30.948 -5.752 1.00 75.00 ? 611 RP5 B "P'" 1 HETATM 10254 O O1X . RP5 U 8 . ? 69.005 -31.939 -6.813 1.00 81.31 -1 611 RP5 B O1X 1 HETATM 10255 O O2X . RP5 U 8 . ? 69.755 -29.729 -5.732 1.00 78.19 ? 611 RP5 B O2X 1 HETATM 10256 O O3X . RP5 U 8 . ? 67.458 -30.319 -5.648 1.00 68.94 ? 611 RP5 B O3X 1 HETATM 10257 O O1 . RP5 U 8 . ? 70.137 -32.288 0.212 1.00 62.71 ? 611 RP5 B O1 1 HETATM 10258 C C1 . NAG V 3 . ? 90.230 26.139 -18.669 1.00 47.91 ? 601 NAG C C1 1 HETATM 10259 C C2 . NAG V 3 . ? 91.078 27.516 -18.554 1.00 46.76 ? 601 NAG C C2 1 HETATM 10260 C C3 . NAG V 3 . ? 92.476 27.478 -19.219 1.00 47.04 ? 601 NAG C C3 1 HETATM 10261 C C4 . NAG V 3 . ? 93.319 26.269 -18.786 1.00 50.25 ? 601 NAG C C4 1 HETATM 10262 C C5 . NAG V 3 . ? 92.573 24.966 -19.243 1.00 51.63 ? 601 NAG C C5 1 HETATM 10263 C C6 . NAG V 3 . ? 93.378 23.730 -18.819 1.00 52.21 ? 601 NAG C C6 1 HETATM 10264 C C7 . NAG V 3 . ? 89.446 29.433 -18.431 1.00 46.23 ? 601 NAG C C7 1 HETATM 10265 C C8 . NAG V 3 . ? 88.837 30.589 -19.238 1.00 47.63 ? 601 NAG C C8 1 HETATM 10266 N N2 . NAG V 3 . ? 90.340 28.676 -19.122 1.00 45.14 ? 601 NAG C N2 1 HETATM 10267 O O3 . NAG V 3 . ? 93.149 28.656 -18.807 1.00 47.32 ? 601 NAG C O3 1 HETATM 10268 O O4 . NAG V 3 . ? 94.732 26.345 -19.301 1.00 47.40 ? 601 NAG C O4 1 HETATM 10269 O O5 . NAG V 3 . ? 91.155 24.904 -18.756 1.00 49.42 ? 601 NAG C O5 1 HETATM 10270 O O6 . NAG V 3 . ? 93.452 23.768 -17.378 1.00 50.29 ? 601 NAG C O6 1 HETATM 10271 O O7 . NAG V 3 . ? 89.102 29.257 -17.258 1.00 43.84 ? 601 NAG C O7 1 HETATM 10272 C C1 . NAG W 3 . ? 64.246 18.654 -27.610 1.00 55.82 ? 602 NAG C C1 1 HETATM 10273 C C2 . NAG W 3 . ? 64.038 17.519 -28.680 1.00 53.84 ? 602 NAG C C2 1 HETATM 10274 C C3 . NAG W 3 . ? 65.138 16.428 -28.546 1.00 52.79 ? 602 NAG C C3 1 HETATM 10275 C C4 . NAG W 3 . ? 66.549 17.002 -28.619 1.00 53.16 ? 602 NAG C C4 1 HETATM 10276 C C5 . NAG W 3 . ? 66.729 18.112 -27.526 1.00 53.78 ? 602 NAG C C5 1 HETATM 10277 C C6 . NAG W 3 . ? 68.121 18.752 -27.615 1.00 52.90 ? 602 NAG C C6 1 HETATM 10278 C C7 . NAG W 3 . ? 61.534 17.504 -28.875 1.00 52.93 ? 602 NAG C C7 1 HETATM 10279 C C8 . NAG W 3 . ? 60.268 16.665 -28.658 1.00 51.78 ? 602 NAG C C8 1 HETATM 10280 N N2 . NAG W 3 . ? 62.698 16.890 -28.536 1.00 53.94 ? 602 NAG C N2 1 HETATM 10281 O O3 . NAG W 3 . ? 65.033 15.480 -29.598 1.00 51.99 ? 602 NAG C O3 1 HETATM 10282 O O4 . NAG W 3 . ? 67.512 15.888 -28.490 1.00 51.29 ? 602 NAG C O4 1 HETATM 10283 O O5 . NAG W 3 . ? 65.670 19.119 -27.645 1.00 54.80 ? 602 NAG C O5 1 HETATM 10284 O O6 . NAG W 3 . ? 67.938 20.134 -27.990 1.00 50.65 ? 602 NAG C O6 1 HETATM 10285 O O7 . NAG W 3 . ? 61.446 18.655 -29.308 1.00 51.21 ? 602 NAG C O7 1 HETATM 10286 C C1 . NAG X 3 . ? 63.618 46.567 4.680 1.00 63.06 ? 603 NAG C C1 1 HETATM 10287 C C2 . NAG X 3 . ? 63.854 47.967 5.284 1.00 63.08 ? 603 NAG C C2 1 HETATM 10288 C C3 . NAG X 3 . ? 62.840 48.979 4.665 1.00 64.15 ? 603 NAG C C3 1 HETATM 10289 C C4 . NAG X 3 . ? 63.180 49.163 3.193 1.00 65.18 ? 603 NAG C C4 1 HETATM 10290 C C5 . NAG X 3 . ? 62.898 47.834 2.473 1.00 68.02 ? 603 NAG C C5 1 HETATM 10291 C C6 . NAG X 3 . ? 63.991 47.525 1.464 1.00 68.45 ? 603 NAG C C6 1 HETATM 10292 C C7 . NAG X 3 . ? 64.845 47.744 7.571 1.00 57.28 ? 603 NAG C C7 1 HETATM 10293 C C8 . NAG X 3 . ? 64.561 47.598 9.071 1.00 54.75 ? 603 NAG C C8 1 HETATM 10294 N N2 . NAG X 3 . ? 63.750 47.836 6.762 1.00 61.39 ? 603 NAG C N2 1 HETATM 10295 O O3 . NAG X 3 . ? 62.905 50.259 5.271 1.00 68.95 ? 603 NAG C O3 1 HETATM 10296 O O4 . NAG X 3 . ? 62.408 50.246 2.610 1.00 56.91 ? 603 NAG C O4 1 HETATM 10297 O O5 . NAG X 3 . ? 62.745 46.708 3.443 1.00 72.46 ? 603 NAG C O5 1 HETATM 10298 O O6 . NAG X 3 . ? 63.548 48.213 0.294 1.00 67.70 ? 603 NAG C O6 1 HETATM 10299 O O7 . NAG X 3 . ? 66.010 47.773 7.173 1.00 53.82 ? 603 NAG C O7 1 HETATM 10300 C C1 . NAG Y 3 . ? 76.958 11.754 -3.513 1.00 49.76 ? 604 NAG C C1 1 HETATM 10301 C C2 . NAG Y 3 . ? 77.005 11.398 -1.956 1.00 49.43 ? 604 NAG C C2 1 HETATM 10302 C C3 . NAG Y 3 . ? 78.411 11.559 -1.319 1.00 49.92 ? 604 NAG C C3 1 HETATM 10303 C C4 . NAG Y 3 . ? 79.463 10.931 -2.192 1.00 51.63 ? 604 NAG C C4 1 HETATM 10304 C C5 . NAG Y 3 . ? 79.341 11.509 -3.634 1.00 50.47 ? 604 NAG C C5 1 HETATM 10305 C C6 . NAG Y 3 . ? 80.373 10.924 -4.561 1.00 52.06 ? 604 NAG C C6 1 HETATM 10306 C C7 . NAG Y 3 . ? 75.944 13.423 -0.775 1.00 54.33 ? 604 NAG C C7 1 HETATM 10307 C C8 . NAG Y 3 . ? 76.936 14.447 -1.380 1.00 51.73 ? 604 NAG C C8 1 HETATM 10308 N N2 . NAG Y 3 . ? 75.997 12.086 -1.102 1.00 49.27 ? 604 NAG C N2 1 HETATM 10309 O O3 . NAG Y 3 . ? 78.417 10.860 -0.074 1.00 47.29 ? 604 NAG C O3 1 HETATM 10310 O O4 . NAG Y 3 . ? 80.806 11.152 -1.603 1.00 53.49 ? 604 NAG C O4 1 HETATM 10311 O O5 . NAG Y 3 . ? 78.102 11.150 -4.222 1.00 47.01 ? 604 NAG C O5 1 HETATM 10312 O O6 . NAG Y 3 . ? 80.717 9.656 -3.992 1.00 52.49 ? 604 NAG C O6 1 HETATM 10313 O O7 . NAG Y 3 . ? 75.080 13.872 -0.020 1.00 55.29 ? 604 NAG C O7 1 HETATM 10314 ZN ZN . ZN Z 4 . ? 62.861 32.616 -11.713 1.00 50.69 ? 605 ZN C ZN 1 HETATM 10315 ZN ZN . ZN AA 4 . ? 64.835 29.315 -12.190 1.00 32.16 ? 606 ZN C ZN 1 HETATM 10316 O O3P . C5P BA 5 . ? 66.027 30.520 -12.294 1.00 53.54 ? 607 C5P C O3P 1 HETATM 10317 P P . C5P BA 5 . ? 65.840 31.887 -11.683 1.00 56.80 ? 607 C5P C P 1 HETATM 10318 O O1P . C5P BA 5 . ? 65.986 33.061 -12.620 1.00 59.29 ? 607 C5P C O1P 1 HETATM 10319 O O2P . C5P BA 5 . ? 64.531 31.973 -10.960 1.00 61.89 -1 607 C5P C O2P 1 HETATM 10320 O "O5'" . C5P BA 5 . ? 67.078 32.097 -10.595 1.00 68.26 ? 607 C5P C "O5'" 1 HETATM 10321 C "C5'" . C5P BA 5 . ? 67.410 31.291 -9.419 1.00 72.72 ? 607 C5P C "C5'" 1 HETATM 10322 C "C4'" . C5P BA 5 . ? 68.862 30.726 -9.194 1.00 75.70 ? 607 C5P C "C4'" 1 HETATM 10323 O "O4'" . C5P BA 5 . ? 69.704 30.635 -10.376 1.00 76.84 ? 607 C5P C "O4'" 1 HETATM 10324 C "C3'" . C5P BA 5 . ? 69.704 31.463 -8.125 1.00 77.10 ? 607 C5P C "C3'" 1 HETATM 10325 O "O3'" . C5P BA 5 . ? 69.623 30.858 -6.819 1.00 67.22 ? 607 C5P C "O3'" 1 HETATM 10326 C "C2'" . C5P BA 5 . ? 71.142 31.505 -8.672 1.00 79.94 ? 607 C5P C "C2'" 1 HETATM 10327 O "O2'" . C5P BA 5 . ? 72.101 30.883 -7.809 1.00 72.85 ? 607 C5P C "O2'" 1 HETATM 10328 C "C1'" . C5P BA 5 . ? 71.104 30.810 -10.043 1.00 81.66 ? 607 C5P C "C1'" 1 HETATM 10329 N N1 . C5P BA 5 . ? 71.923 31.502 -11.108 1.00 86.76 ? 607 C5P C N1 1 HETATM 10330 C C2 . C5P BA 5 . ? 71.774 32.854 -11.593 1.00 84.51 ? 607 C5P C C2 1 HETATM 10331 N N3 . C5P BA 5 . ? 72.594 33.342 -12.564 1.00 80.76 ? 607 C5P C N3 1 HETATM 10332 C C4 . C5P BA 5 . ? 73.566 32.579 -13.112 1.00 77.49 ? 607 C5P C C4 1 HETATM 10333 C C5 . C5P BA 5 . ? 73.741 31.277 -12.680 1.00 83.53 ? 607 C5P C C5 1 HETATM 10334 C C6 . C5P BA 5 . ? 72.908 30.771 -11.675 1.00 90.44 ? 607 C5P C C6 1 HETATM 10335 O O2 . C5P BA 5 . ? 70.911 33.651 -11.169 1.00 86.15 ? 607 C5P C O2 1 HETATM 10336 N N4 . C5P BA 5 . ? 74.371 33.065 -14.069 1.00 69.38 ? 607 C5P C N4 1 HETATM 10337 S S . SCN CA 9 . ? 50.170 21.181 17.672 1.00 48.96 ? 608 SCN C S 1 HETATM 10338 C C . SCN CA 9 . ? 50.591 20.226 16.610 1.00 44.45 ? 608 SCN C C 1 HETATM 10339 N N . SCN CA 9 . ? 50.919 19.469 15.784 1.00 36.47 ? 608 SCN C N 1 HETATM 10340 S S . SCN DA 9 . ? 70.722 39.187 -16.107 1.00 52.95 ? 609 SCN C S 1 HETATM 10341 C C . SCN DA 9 . ? 71.073 38.894 -17.511 1.00 43.88 ? 609 SCN C C 1 HETATM 10342 N N . SCN DA 9 . ? 71.349 38.642 -18.589 1.00 40.21 ? 609 SCN C N 1 HETATM 10343 O O . HOH EA 10 . ? 14.463 -7.596 2.544 1.00 15.18 ? 701 HOH A O 1 HETATM 10344 O O . HOH EA 10 . ? 24.508 5.096 2.211 1.00 12.86 ? 702 HOH A O 1 HETATM 10345 O O . HOH EA 10 . ? 4.678 -1.519 15.794 1.00 13.40 ? 703 HOH A O 1 HETATM 10346 O O . HOH EA 10 . ? 18.353 11.348 -12.682 1.00 13.16 ? 704 HOH A O 1 HETATM 10347 O O . HOH EA 10 . ? 12.115 -10.673 0.802 1.00 6.90 ? 705 HOH A O 1 HETATM 10348 O O . HOH EA 10 . ? 21.351 -5.479 -15.582 1.00 17.36 ? 706 HOH A O 1 HETATM 10349 O O . HOH EA 10 . ? 25.679 10.690 -26.579 1.00 16.20 ? 707 HOH A O 1 HETATM 10350 O O . HOH EA 10 . ? 19.265 -1.299 -4.597 1.00 21.26 ? 708 HOH A O 1 HETATM 10351 O O . HOH EA 10 . ? 21.133 -13.510 -11.830 1.00 19.37 ? 709 HOH A O 1 HETATM 10352 O O . HOH EA 10 . ? 8.016 -5.502 5.837 1.00 27.78 ? 710 HOH A O 1 HETATM 10353 O O . HOH EA 10 . ? 24.956 1.059 -6.837 1.00 26.88 ? 711 HOH A O 1 HETATM 10354 O O . HOH EA 10 . ? 25.943 -4.910 -0.464 1.00 8.65 ? 712 HOH A O 1 HETATM 10355 O O . HOH EA 10 . ? 9.181 6.505 -10.890 1.00 4.93 ? 713 HOH A O 1 HETATM 10356 O O . HOH EA 10 . ? 22.116 2.889 6.014 1.00 6.54 ? 714 HOH A O 1 HETATM 10357 O O . HOH EA 10 . ? 7.750 2.903 -14.997 1.00 13.49 ? 715 HOH A O 1 HETATM 10358 O O . HOH EA 10 . ? 9.048 -0.622 -10.283 1.00 8.59 ? 716 HOH A O 1 HETATM 10359 O O . HOH EA 10 . ? 17.262 -2.917 6.923 1.00 2.00 ? 717 HOH A O 1 HETATM 10360 O O . HOH EA 10 . ? 9.553 -24.448 -12.603 1.00 13.60 ? 718 HOH A O 1 HETATM 10361 O O . HOH EA 10 . ? -6.830 -0.546 17.950 1.00 16.06 ? 719 HOH A O 1 HETATM 10362 O O . HOH FA 10 . ? 62.707 -27.306 -7.485 1.00 21.15 ? 701 HOH B O 1 HETATM 10363 O O . HOH FA 10 . ? 62.105 -38.662 -22.051 1.00 41.75 ? 702 HOH B O 1 HETATM 10364 O O . HOH FA 10 . ? 59.051 -22.422 10.228 1.00 9.15 ? 703 HOH B O 1 HETATM 10365 O O . HOH FA 10 . ? 65.005 -25.169 -1.881 1.00 20.34 ? 704 HOH B O 1 HETATM 10366 O O . HOH FA 10 . ? 74.379 -26.200 10.523 1.00 29.77 ? 705 HOH B O 1 HETATM 10367 O O . HOH FA 10 . ? 76.784 -26.250 3.731 1.00 16.12 ? 706 HOH B O 1 HETATM 10368 O O . HOH FA 10 . ? 60.508 -21.231 -3.315 1.00 28.50 ? 707 HOH B O 1 HETATM 10369 O O . HOH FA 10 . ? 61.824 -7.558 -14.670 1.00 29.96 ? 708 HOH B O 1 HETATM 10370 O O . HOH FA 10 . ? 55.818 -28.674 -22.537 1.00 21.35 ? 709 HOH B O 1 HETATM 10371 O O . HOH FA 10 . ? 57.346 -24.059 4.885 1.00 45.43 ? 710 HOH B O 1 HETATM 10372 O O . HOH FA 10 . ? 67.578 -21.576 -12.692 1.00 28.69 ? 711 HOH B O 1 HETATM 10373 O O . HOH FA 10 . ? 59.719 -25.042 9.099 1.00 11.78 ? 712 HOH B O 1 HETATM 10374 O O . HOH FA 10 . ? 68.698 -30.793 -14.538 1.00 23.45 ? 713 HOH B O 1 HETATM 10375 O O . HOH FA 10 . ? 76.359 -4.237 -12.309 1.00 20.84 ? 714 HOH B O 1 HETATM 10376 O O . HOH FA 10 . ? 81.673 -27.973 8.394 1.00 12.41 ? 715 HOH B O 1 HETATM 10377 O O . HOH FA 10 . ? 74.589 -32.582 9.222 1.00 42.67 ? 716 HOH B O 1 HETATM 10378 O O . HOH FA 10 . ? 61.510 -20.242 8.653 1.00 11.99 ? 717 HOH B O 1 HETATM 10379 O O . HOH FA 10 . ? 60.542 -41.821 -8.919 1.00 8.26 ? 718 HOH B O 1 HETATM 10380 O O . HOH FA 10 . ? 56.014 -5.275 -12.357 1.00 17.28 ? 719 HOH B O 1 HETATM 10381 O O . HOH FA 10 . ? 86.235 -6.135 -6.431 1.00 11.19 ? 720 HOH B O 1 HETATM 10382 O O . HOH FA 10 . ? 77.876 -32.885 -0.372 1.00 25.77 ? 721 HOH B O 1 HETATM 10383 O O . HOH FA 10 . ? 64.516 -2.745 -6.880 1.00 17.14 ? 722 HOH B O 1 HETATM 10384 O O . HOH FA 10 . ? 85.738 -15.931 -11.784 1.00 15.54 ? 723 HOH B O 1 HETATM 10385 O O . HOH FA 10 . ? 77.276 -28.588 -7.995 1.00 24.36 ? 724 HOH B O 1 HETATM 10386 O O . HOH FA 10 . ? 69.396 -2.713 -14.244 1.00 4.35 ? 725 HOH B O 1 HETATM 10387 O O . HOH FA 10 . ? 50.636 -10.814 -17.133 1.00 32.49 ? 726 HOH B O 1 HETATM 10388 O O . HOH FA 10 . ? 67.662 -27.118 5.036 1.00 22.82 ? 727 HOH B O 1 HETATM 10389 O O . HOH FA 10 . ? 68.222 -32.006 4.980 1.00 13.18 ? 728 HOH B O 1 HETATM 10390 O O . HOH FA 10 . ? 63.529 -19.892 6.983 1.00 18.52 ? 729 HOH B O 1 HETATM 10391 O O . HOH FA 10 . ? 79.752 -4.614 -23.086 1.00 35.98 ? 730 HOH B O 1 HETATM 10392 O O . HOH FA 10 . ? 47.022 -19.926 -11.964 1.00 15.95 ? 731 HOH B O 1 HETATM 10393 O O . HOH FA 10 . ? 55.212 -10.343 -23.729 1.00 12.89 ? 732 HOH B O 1 HETATM 10394 O O . HOH FA 10 . ? 62.590 -41.049 23.905 1.00 15.46 ? 733 HOH B O 1 HETATM 10395 O O . HOH FA 10 . ? 73.770 -4.943 -18.758 1.00 7.09 ? 734 HOH B O 1 HETATM 10396 O O . HOH FA 10 . ? 69.673 -23.891 -30.722 1.00 21.23 ? 735 HOH B O 1 HETATM 10397 O O . HOH FA 10 . ? 69.934 -15.195 -23.970 1.00 24.05 ? 736 HOH B O 1 HETATM 10398 O O . HOH FA 10 . ? 55.047 -26.493 24.857 1.00 19.48 ? 737 HOH B O 1 HETATM 10399 O O . HOH FA 10 . ? 58.603 -0.415 -4.024 1.00 24.87 ? 738 HOH B O 1 HETATM 10400 O O . HOH FA 10 . ? 65.322 0.143 -13.217 1.00 20.62 ? 739 HOH B O 1 HETATM 10401 O O . HOH FA 10 . ? 82.581 -26.645 21.480 1.00 26.36 ? 740 HOH B O 1 HETATM 10402 O O . HOH FA 10 . ? 81.050 -25.274 -22.281 1.00 17.40 ? 741 HOH B O 1 HETATM 10403 O O . HOH FA 10 . ? 59.232 -12.204 -24.356 1.00 16.19 ? 742 HOH B O 1 HETATM 10404 O O . HOH FA 10 . ? 46.725 -31.484 -16.598 1.00 25.85 ? 743 HOH B O 1 HETATM 10405 O O . HOH FA 10 . ? 82.353 -36.355 3.059 1.00 17.37 ? 744 HOH B O 1 HETATM 10406 O O . HOH FA 10 . ? 80.330 -3.408 -8.362 1.00 16.74 ? 745 HOH B O 1 HETATM 10407 O O . HOH FA 10 . ? 88.169 -17.107 -16.023 1.00 18.84 ? 746 HOH B O 1 HETATM 10408 O O . HOH FA 10 . ? 73.862 -12.626 -28.718 1.00 16.60 ? 747 HOH B O 1 HETATM 10409 O O . HOH FA 10 . ? 50.881 -7.140 -12.051 1.00 28.80 ? 748 HOH B O 1 HETATM 10410 O O . HOH FA 10 . ? 56.765 -37.246 -23.044 1.00 18.63 ? 749 HOH B O 1 HETATM 10411 O O . HOH FA 10 . ? 72.961 -35.720 0.590 1.00 25.74 ? 750 HOH B O 1 HETATM 10412 O O . HOH FA 10 . ? 63.481 -16.346 -26.257 1.00 20.32 ? 751 HOH B O 1 HETATM 10413 O O . HOH FA 10 . ? 83.138 -41.936 16.679 1.00 15.92 ? 752 HOH B O 1 HETATM 10414 O O . HOH FA 10 . ? 66.121 -8.920 -23.305 1.00 10.92 ? 753 HOH B O 1 HETATM 10415 O O . HOH FA 10 . ? 88.107 -13.359 -11.717 1.00 17.82 ? 754 HOH B O 1 HETATM 10416 O O . HOH FA 10 . ? 57.082 -15.451 25.843 1.00 19.75 ? 755 HOH B O 1 HETATM 10417 O O . HOH FA 10 . ? 66.283 -23.632 -31.103 1.00 25.06 ? 756 HOH B O 1 HETATM 10418 O O . HOH FA 10 . ? 77.409 12.100 7.945 1.00 7.90 ? 757 HOH B O 1 HETATM 10419 O O . HOH FA 10 . ? 69.756 -12.374 -28.146 1.00 20.90 ? 758 HOH B O 1 HETATM 10420 O O . HOH FA 10 . ? 60.982 -15.393 -27.888 1.00 35.54 ? 759 HOH B O 1 HETATM 10421 O O . HOH FA 10 . ? 58.548 -6.251 -24.513 1.00 31.51 ? 760 HOH B O 1 HETATM 10422 O O . HOH GA 10 . ? 76.500 25.403 -11.263 1.00 32.49 ? 701 HOH C O 1 HETATM 10423 O O . HOH GA 10 . ? 62.516 32.662 -2.863 1.00 30.00 ? 702 HOH C O 1 HETATM 10424 O O . HOH GA 10 . ? 51.488 31.859 -15.197 1.00 18.32 ? 703 HOH C O 1 HETATM 10425 O O . HOH GA 10 . ? 58.589 5.957 -5.164 1.00 30.00 ? 704 HOH C O 1 HETATM 10426 O O . HOH GA 10 . ? 70.347 25.776 -8.962 1.00 17.94 ? 705 HOH C O 1 HETATM 10427 O O . HOH GA 10 . ? 66.100 19.104 -0.659 1.00 16.29 ? 706 HOH C O 1 HETATM 10428 O O . HOH GA 10 . ? 58.320 26.691 -18.809 1.00 22.62 ? 707 HOH C O 1 HETATM 10429 O O . HOH GA 10 . ? 66.147 11.497 8.743 1.00 25.26 ? 708 HOH C O 1 HETATM 10430 O O . HOH GA 10 . ? 76.056 16.135 -6.918 1.00 25.79 ? 709 HOH C O 1 HETATM 10431 O O . HOH GA 10 . ? 50.820 39.481 9.843 1.00 25.99 ? 710 HOH C O 1 HETATM 10432 O O . HOH GA 10 . ? 74.552 20.856 -15.838 1.00 24.23 ? 711 HOH C O 1 HETATM 10433 O O . HOH GA 10 . ? 84.599 25.358 -13.119 1.00 27.49 ? 712 HOH C O 1 HETATM 10434 O O . HOH GA 10 . ? 63.036 26.771 -7.580 1.00 17.63 ? 713 HOH C O 1 HETATM 10435 O O . HOH GA 10 . ? 42.208 25.487 4.532 1.00 15.16 ? 714 HOH C O 1 HETATM 10436 O O . HOH GA 10 . ? 64.153 28.885 4.005 1.00 18.63 ? 715 HOH C O 1 HETATM 10437 O O . HOH GA 10 . ? 86.463 21.264 -11.066 1.00 19.38 ? 716 HOH C O 1 HETATM 10438 O O . HOH GA 10 . ? 66.817 15.638 13.315 1.00 11.97 ? 717 HOH C O 1 HETATM 10439 O O . HOH GA 10 . ? 47.531 29.047 17.890 1.00 24.22 ? 718 HOH C O 1 HETATM 10440 O O . HOH GA 10 . ? 46.854 13.794 8.791 1.00 35.68 ? 719 HOH C O 1 HETATM 10441 O O . HOH GA 10 . ? 62.444 20.648 -9.990 1.00 29.22 ? 720 HOH C O 1 HETATM 10442 O O . HOH GA 10 . ? 72.942 17.400 3.317 1.00 14.17 ? 721 HOH C O 1 HETATM 10443 O O . HOH GA 10 . ? 56.544 22.574 -3.739 1.00 13.39 ? 722 HOH C O 1 HETATM 10444 O O . HOH GA 10 . ? 63.116 29.901 -0.201 1.00 21.73 ? 723 HOH C O 1 HETATM 10445 O O . HOH GA 10 . ? 59.625 28.353 1.734 1.00 87.38 ? 724 HOH C O 1 HETATM 10446 O O . HOH GA 10 . ? 73.641 36.122 -12.387 1.00 20.74 ? 725 HOH C O 1 HETATM 10447 O O . HOH GA 10 . ? 43.618 12.619 7.488 1.00 28.93 ? 726 HOH C O 1 HETATM 10448 O O . HOH GA 10 . ? 69.355 21.108 19.930 1.00 7.18 ? 727 HOH C O 1 HETATM 10449 O O . HOH GA 10 . ? 64.442 21.561 3.606 1.00 4.28 ? 728 HOH C O 1 HETATM 10450 O O . HOH GA 10 . ? 57.965 38.048 -2.072 1.00 22.45 ? 729 HOH C O 1 HETATM 10451 O O . HOH GA 10 . ? 66.782 31.840 -1.878 1.00 21.21 ? 730 HOH C O 1 HETATM 10452 O O . HOH GA 10 . ? 55.871 35.769 14.403 1.00 7.48 ? 731 HOH C O 1 HETATM 10453 O O . HOH GA 10 . ? 71.502 34.982 -17.733 1.00 12.08 ? 732 HOH C O 1 HETATM 10454 O O . HOH GA 10 . ? 49.568 41.544 7.922 1.00 12.13 ? 733 HOH C O 1 HETATM 10455 O O . HOH GA 10 . ? 70.233 13.075 5.542 1.00 2.00 ? 734 HOH C O 1 HETATM 10456 O O . HOH GA 10 . ? 53.700 17.850 13.858 1.00 30.00 ? 735 HOH C O 1 HETATM 10457 O O . HOH GA 10 . ? 44.026 27.179 9.170 1.00 14.16 ? 736 HOH C O 1 HETATM 10458 O O . HOH GA 10 . ? 66.363 31.384 17.199 1.00 8.48 ? 737 HOH C O 1 HETATM 10459 O O . HOH GA 10 . ? 69.626 7.883 -1.238 1.00 26.70 ? 738 HOH C O 1 HETATM 10460 O O . HOH GA 10 . ? 68.795 31.176 19.970 1.00 15.26 ? 739 HOH C O 1 HETATM 10461 O O . HOH GA 10 . ? 67.746 34.227 -7.570 1.00 10.78 ? 740 HOH C O 1 HETATM 10462 O O . HOH GA 10 . ? 69.059 43.483 12.947 1.00 16.02 ? 741 HOH C O 1 HETATM 10463 O O . HOH GA 10 . ? 60.458 32.488 15.520 1.00 7.64 ? 742 HOH C O 1 HETATM 10464 O O . HOH GA 10 . ? 60.159 40.988 -29.896 1.00 30.00 ? 743 HOH C O 1 HETATM 10465 O O . HOH GA 10 . ? 52.284 8.454 5.008 1.00 11.88 ? 744 HOH C O 1 HETATM 10466 O O . HOH GA 10 . ? 68.721 42.478 -27.037 1.00 22.34 ? 745 HOH C O 1 HETATM 10467 O O . HOH GA 10 . ? 38.798 8.780 0.251 1.00 13.75 ? 746 HOH C O 1 HETATM 10468 O O . HOH GA 10 . ? 39.056 34.612 8.233 1.00 9.15 ? 747 HOH C O 1 HETATM 10469 O O . HOH GA 10 . ? 62.551 14.241 19.241 1.00 20.05 ? 748 HOH C O 1 HETATM 10470 O O . HOH GA 10 . ? 58.453 4.519 -0.565 1.00 2.00 ? 749 HOH C O 1 HETATM 10471 O O . HOH GA 10 . ? 48.626 28.346 20.627 1.00 3.56 ? 750 HOH C O 1 HETATM 10472 O O . HOH GA 10 . ? 54.389 21.468 20.655 1.00 8.76 ? 751 HOH C O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 PRO 1 33 33 PRO PRO A . n A 1 2 PRO 2 34 34 PRO PRO A . n A 1 3 PRO 3 35 35 PRO PRO A . n A 1 4 ALA 4 36 36 ALA ALA A . n A 1 5 ILE 5 37 37 ILE ILE A . n A 1 6 GLY 6 38 38 GLY GLY A . n A 1 7 GLN 7 39 39 GLN GLN A . n A 1 8 PHE 8 40 40 PHE PHE A . n A 1 9 TRP 9 41 41 TRP TRP A . n A 1 10 HIS 10 42 42 HIS HIS A . n A 1 11 VAL 11 43 43 VAL VAL A . n A 1 12 THR 12 44 44 THR THR A . n A 1 13 ASP 13 45 45 ASP ASP A . n A 1 14 LEU 14 46 46 LEU LEU A . n A 1 15 HIS 15 47 47 HIS HIS A . n A 1 16 LEU 16 48 48 LEU LEU A . n A 1 17 ASP 17 49 49 ASP ASP A . n A 1 18 PRO 18 50 50 PRO PRO A . n A 1 19 THR 19 51 51 THR THR A . n A 1 20 TYR 20 52 52 TYR TYR A . n A 1 21 HIS 21 53 53 HIS HIS A . n A 1 22 ILE 22 54 54 ILE ILE A . n A 1 23 THR 23 55 55 THR THR A . n A 1 24 ASP 24 56 56 ASP ASP A . n A 1 25 ASP 25 57 57 ASP ASP A . n A 1 26 HIS 26 58 58 HIS HIS A . n A 1 27 THR 27 59 59 THR THR A . n A 1 28 LYS 28 60 60 LYS LYS A . n A 1 29 VAL 29 61 61 VAL VAL A . n A 1 30 CYS 30 62 62 CYS CYS A . n A 1 31 ALA 31 63 63 ALA ALA A . n A 1 32 SER 32 64 64 SER SER A . n A 1 33 SER 33 65 65 SER SER A . n A 1 34 LYS 34 66 66 LYS LYS A . n A 1 35 GLY 35 67 67 GLY GLY A . n A 1 36 ALA 36 68 68 ALA ALA A . n A 1 37 ASN 37 69 69 ASN ASN A . n A 1 38 ALA 38 70 70 ALA ALA A . n A 1 39 SER 39 71 71 SER SER A . n A 1 40 ASN 40 72 72 ASN ASN A . n A 1 41 PRO 41 73 73 PRO PRO A . n A 1 42 GLY 42 74 74 GLY GLY A . n A 1 43 PRO 43 75 75 PRO PRO A . n A 1 44 PHE 44 76 76 PHE PHE A . n A 1 45 GLY 45 77 77 GLY GLY A . n A 1 46 ASP 46 78 78 ASP ASP A . n A 1 47 VAL 47 79 79 VAL VAL A . n A 1 48 LEU 48 80 80 LEU LEU A . n A 1 49 CYS 49 81 81 CYS CYS A . n A 1 50 ASP 50 82 82 ASP ASP A . n A 1 51 SER 51 83 83 SER SER A . n A 1 52 PRO 52 84 84 PRO PRO A . n A 1 53 TYR 53 85 85 TYR TYR A . n A 1 54 GLN 54 86 86 GLN GLN A . n A 1 55 LEU 55 87 87 LEU LEU A . n A 1 56 ILE 56 88 88 ILE ILE A . n A 1 57 LEU 57 89 89 LEU LEU A . n A 1 58 SER 58 90 90 SER SER A . n A 1 59 ALA 59 91 91 ALA ALA A . n A 1 60 PHE 60 92 92 PHE PHE A . n A 1 61 ASP 61 93 93 ASP ASP A . n A 1 62 PHE 62 94 94 PHE PHE A . n A 1 63 ILE 63 95 95 ILE ILE A . n A 1 64 LYS 64 96 96 LYS LYS A . n A 1 65 ASN 65 97 97 ASN ASN A . n A 1 66 SER 66 98 98 SER SER A . n A 1 67 GLY 67 99 99 GLY GLY A . n A 1 68 GLN 68 100 100 GLN GLN A . n A 1 69 GLU 69 101 101 GLU GLU A . n A 1 70 ALA 70 102 102 ALA ALA A . n A 1 71 SER 71 103 103 SER SER A . n A 1 72 PHE 72 104 104 PHE PHE A . n A 1 73 MET 73 105 105 MET MET A . n A 1 74 ILE 74 106 106 ILE ILE A . n A 1 75 TRP 75 107 107 TRP TRP A . n A 1 76 THR 76 108 108 THR THR A . n A 1 77 GLY 77 109 109 GLY GLY A . n A 1 78 ASP 78 110 110 ASP ASP A . n A 1 79 SER 79 111 111 SER SER A . n A 1 80 PRO 80 112 112 PRO PRO A . n A 1 81 PRO 81 113 113 PRO PRO A . n A 1 82 HIS 82 114 114 HIS HIS A . n A 1 83 VAL 83 115 115 VAL VAL A . n A 1 84 PRO 84 116 116 PRO PRO A . n A 1 85 VAL 85 117 117 VAL VAL A . n A 1 86 PRO 86 118 118 PRO PRO A . n A 1 87 GLU 87 119 119 GLU GLU A . n A 1 88 LEU 88 120 120 LEU LEU A . n A 1 89 SER 89 121 121 SER SER A . n A 1 90 THR 90 122 122 THR THR A . n A 1 91 ASP 91 123 123 ASP ASP A . n A 1 92 THR 92 124 124 THR THR A . n A 1 93 VAL 93 125 125 VAL VAL A . n A 1 94 ILE 94 126 126 ILE ILE A . n A 1 95 ASN 95 127 127 ASN ASN A . n A 1 96 VAL 96 128 128 VAL VAL A . n A 1 97 ILE 97 129 129 ILE ILE A . n A 1 98 THR 98 130 130 THR THR A . n A 1 99 ASN 99 131 131 ASN ASN A . n A 1 100 MET 100 132 132 MET MET A . n A 1 101 THR 101 133 133 THR THR A . n A 1 102 THR 102 134 134 THR THR A . n A 1 103 THR 103 135 135 THR THR A . n A 1 104 ILE 104 136 136 ILE ILE A . n A 1 105 GLN 105 137 137 GLN GLN A . n A 1 106 SER 106 138 138 SER SER A . n A 1 107 LEU 107 139 139 LEU LEU A . n A 1 108 PHE 108 140 140 PHE PHE A . n A 1 109 PRO 109 141 141 PRO PRO A . n A 1 110 ASN 110 142 142 ASN ASN A . n A 1 111 LEU 111 143 143 LEU LEU A . n A 1 112 GLN 112 144 144 GLN GLN A . n A 1 113 VAL 113 145 145 VAL VAL A . n A 1 114 PHE 114 146 146 PHE PHE A . n A 1 115 PRO 115 147 147 PRO PRO A . n A 1 116 ALA 116 148 148 ALA ALA A . n A 1 117 LEU 117 149 149 LEU LEU A . n A 1 118 GLY 118 150 150 GLY GLY A . n A 1 119 ASN 119 151 151 ASN ASN A . n A 1 120 HIS 120 152 152 HIS HIS A . n A 1 121 ASP 121 153 153 ASP ASP A . n A 1 122 TYR 122 154 154 TYR TYR A . n A 1 123 TRP 123 155 155 TRP TRP A . n A 1 124 PRO 124 156 156 PRO PRO A . n A 1 125 GLN 125 157 157 GLN GLN A . n A 1 126 ASP 126 158 158 ASP ASP A . n A 1 127 GLN 127 159 159 GLN GLN A . n A 1 128 LEU 128 160 160 LEU LEU A . n A 1 129 PRO 129 161 161 PRO PRO A . n A 1 130 VAL 130 162 162 VAL VAL A . n A 1 131 VAL 131 163 163 VAL VAL A . n A 1 132 THR 132 164 164 THR THR A . n A 1 133 SER 133 165 165 SER SER A . n A 1 134 LYS 134 166 166 LYS LYS A . n A 1 135 VAL 135 167 167 VAL VAL A . n A 1 136 TYR 136 168 168 TYR TYR A . n A 1 137 ASN 137 169 169 ASN ASN A . n A 1 138 ALA 138 170 170 ALA ALA A . n A 1 139 VAL 139 171 171 VAL VAL A . n A 1 140 ALA 140 172 172 ALA ALA A . n A 1 141 ASN 141 173 173 ASN ASN A . n A 1 142 LEU 142 174 174 LEU LEU A . n A 1 143 TRP 143 175 175 TRP TRP A . n A 1 144 LYS 144 176 176 LYS LYS A . n A 1 145 PRO 145 177 177 PRO PRO A . n A 1 146 TRP 146 178 178 TRP TRP A . n A 1 147 LEU 147 179 179 LEU LEU A . n A 1 148 ASP 148 180 180 ASP ASP A . n A 1 149 GLU 149 181 181 GLU GLU A . n A 1 150 GLU 150 182 182 GLU GLU A . n A 1 151 ALA 151 183 183 ALA ALA A . n A 1 152 ILE 152 184 184 ILE ILE A . n A 1 153 SER 153 185 185 SER SER A . n A 1 154 THR 154 186 186 THR THR A . n A 1 155 LEU 155 187 187 LEU LEU A . n A 1 156 ARG 156 188 188 ARG ARG A . n A 1 157 LYS 157 189 189 LYS LYS A . n A 1 158 GLY 158 190 190 GLY GLY A . n A 1 159 GLY 159 191 191 GLY GLY A . n A 1 160 PHE 160 192 192 PHE PHE A . n A 1 161 TYR 161 193 193 TYR TYR A . n A 1 162 SER 162 194 194 SER SER A . n A 1 163 GLN 163 195 195 GLN GLN A . n A 1 164 LYS 164 196 196 LYS LYS A . n A 1 165 VAL 165 197 197 VAL VAL A . n A 1 166 THR 166 198 198 THR THR A . n A 1 167 THR 167 199 199 THR THR A . n A 1 168 ASN 168 200 200 ASN ASN A . n A 1 169 PRO 169 201 201 PRO PRO A . n A 1 170 ASN 170 202 202 ASN ASN A . n A 1 171 LEU 171 203 203 LEU LEU A . n A 1 172 ARG 172 204 204 ARG ARG A . n A 1 173 ILE 173 205 205 ILE ILE A . n A 1 174 ILE 174 206 206 ILE ILE A . n A 1 175 SER 175 207 207 SER SER A . n A 1 176 LEU 176 208 208 LEU LEU A . n A 1 177 ASN 177 209 209 ASN ASN A . n A 1 178 THR 178 210 210 THR THR A . n A 1 179 ASN 179 211 211 ASN ASN A . n A 1 180 LEU 180 212 212 LEU LEU A . n A 1 181 TYR 181 213 213 TYR TYR A . n A 1 182 TYR 182 214 214 TYR TYR A . n A 1 183 GLY 183 215 215 GLY GLY A . n A 1 184 PRO 184 216 216 PRO PRO A . n A 1 185 ASN 185 217 217 ASN ASN A . n A 1 186 ILE 186 218 218 ILE ILE A . n A 1 187 MET 187 219 219 MET MET A . n A 1 188 THR 188 220 220 THR THR A . n A 1 189 LEU 189 221 221 LEU LEU A . n A 1 190 ASN 190 222 222 ASN ASN A . n A 1 191 LYS 191 223 223 LYS LYS A . n A 1 192 THR 192 224 224 THR THR A . n A 1 193 ASP 193 225 225 ASP ASP A . n A 1 194 PRO 194 226 226 PRO PRO A . n A 1 195 ALA 195 227 227 ALA ALA A . n A 1 196 ASN 196 228 228 ASN ASN A . n A 1 197 GLN 197 229 229 GLN GLN A . n A 1 198 PHE 198 230 230 PHE PHE A . n A 1 199 GLU 199 231 231 GLU GLU A . n A 1 200 TRP 200 232 232 TRP TRP A . n A 1 201 LEU 201 233 233 LEU LEU A . n A 1 202 GLU 202 234 234 GLU GLU A . n A 1 203 SER 203 235 235 SER SER A . n A 1 204 THR 204 236 236 THR THR A . n A 1 205 LEU 205 237 237 LEU LEU A . n A 1 206 ASN 206 238 238 ASN ASN A . n A 1 207 ASN 207 239 239 ASN ASN A . n A 1 208 SER 208 240 240 SER SER A . n A 1 209 GLN 209 241 241 GLN GLN A . n A 1 210 GLN 210 242 242 GLN GLN A . n A 1 211 ASN 211 243 243 ASN ASN A . n A 1 212 LYS 212 244 244 LYS LYS A . n A 1 213 GLU 213 245 245 GLU GLU A . n A 1 214 LYS 214 246 246 LYS LYS A . n A 1 215 VAL 215 247 247 VAL VAL A . n A 1 216 TYR 216 248 248 TYR TYR A . n A 1 217 ILE 217 249 249 ILE ILE A . n A 1 218 ILE 218 250 250 ILE ILE A . n A 1 219 ALA 219 251 251 ALA ALA A . n A 1 220 HIS 220 252 252 HIS HIS A . n A 1 221 VAL 221 253 253 VAL VAL A . n A 1 222 PRO 222 254 254 PRO PRO A . n A 1 223 VAL 223 255 255 VAL VAL A . n A 1 224 GLY 224 256 256 GLY GLY A . n A 1 225 TYR 225 257 257 TYR TYR A . n A 1 226 LEU 226 258 258 LEU LEU A . n A 1 227 PRO 227 259 259 PRO PRO A . n A 1 228 SER 228 260 260 SER SER A . n A 1 229 SER 229 261 261 SER SER A . n A 1 230 GLN 230 262 262 GLN GLN A . n A 1 231 ASN 231 263 263 ASN ASN A . n A 1 232 ILE 232 264 264 ILE ILE A . n A 1 233 THR 233 265 265 THR THR A . n A 1 234 ALA 234 266 266 ALA ALA A . n A 1 235 MET 235 267 267 MET MET A . n A 1 236 ARG 236 268 268 ARG ARG A . n A 1 237 GLU 237 269 269 GLU GLU A . n A 1 238 TYR 238 270 270 TYR TYR A . n A 1 239 TYR 239 271 271 TYR TYR A . n A 1 240 ASN 240 272 272 ASN ASN A . n A 1 241 GLU 241 273 273 GLU GLU A . n A 1 242 LYS 242 274 274 LYS LYS A . n A 1 243 LEU 243 275 275 LEU LEU A . n A 1 244 ILE 244 276 276 ILE ILE A . n A 1 245 ASP 245 277 277 ASP ASP A . n A 1 246 ILE 246 278 278 ILE ILE A . n A 1 247 PHE 247 279 279 PHE PHE A . n A 1 248 GLN 248 280 280 GLN GLN A . n A 1 249 LYS 249 281 281 LYS LYS A . n A 1 250 TYR 250 282 282 TYR TYR A . n A 1 251 SER 251 283 283 SER SER A . n A 1 252 ASP 252 284 284 ASP ASP A . n A 1 253 VAL 253 285 285 VAL VAL A . n A 1 254 ILE 254 286 286 ILE ILE A . n A 1 255 ALA 255 287 287 ALA ALA A . n A 1 256 GLY 256 288 288 GLY GLY A . n A 1 257 GLN 257 289 289 GLN GLN A . n A 1 258 PHE 258 290 290 PHE PHE A . n A 1 259 TYR 259 291 291 TYR TYR A . n A 1 260 GLY 260 292 292 GLY GLY A . n A 1 261 HIS 261 293 293 HIS HIS A . n A 1 262 THR 262 294 294 THR THR A . n A 1 263 HIS 263 295 295 HIS HIS A . n A 1 264 ARG 264 296 296 ARG ARG A . n A 1 265 ASP 265 297 297 ASP ASP A . n A 1 266 SER 266 298 298 SER SER A . n A 1 267 ILE 267 299 299 ILE ILE A . n A 1 268 MET 268 300 300 MET MET A . n A 1 269 VAL 269 301 301 VAL VAL A . n A 1 270 LEU 270 302 302 LEU LEU A . n A 1 271 SER 271 303 303 SER SER A . n A 1 272 ASP 272 304 304 ASP ASP A . n A 1 273 LYS 273 305 305 LYS LYS A . n A 1 274 LYS 274 306 306 LYS LYS A . n A 1 275 GLY 275 307 307 GLY GLY A . n A 1 276 SER 276 308 308 SER SER A . n A 1 277 PRO 277 309 309 PRO PRO A . n A 1 278 VAL 278 310 310 VAL VAL A . n A 1 279 ASN 279 311 311 ASN ASN A . n A 1 280 SER 280 312 312 SER SER A . n A 1 281 LEU 281 313 313 LEU LEU A . n A 1 282 PHE 282 314 314 PHE PHE A . n A 1 283 VAL 283 315 315 VAL VAL A . n A 1 284 ALA 284 316 316 ALA ALA A . n A 1 285 PRO 285 317 317 PRO PRO A . n A 1 286 ALA 286 318 318 ALA ALA A . n A 1 287 VAL 287 319 319 VAL VAL A . n A 1 288 THR 288 320 320 THR THR A . n A 1 289 PRO 289 321 321 PRO PRO A . n A 1 290 VAL 290 322 322 VAL VAL A . n A 1 291 LYS 291 323 323 LYS LYS A . n A 1 292 SER 292 324 324 SER SER A . n A 1 293 VAL 293 325 325 VAL VAL A . n A 1 294 LEU 294 326 326 LEU LEU A . n A 1 295 GLU 295 327 327 GLU GLU A . n A 1 296 LYS 296 328 328 LYS LYS A . n A 1 297 GLN 297 329 329 GLN GLN A . n A 1 298 THR 298 330 330 THR THR A . n A 1 299 ASN 299 331 331 ASN ASN A . n A 1 300 ASN 300 332 332 ASN ASN A . n A 1 301 PRO 301 333 333 PRO PRO A . n A 1 302 GLY 302 334 334 GLY GLY A . n A 1 303 ILE 303 335 335 ILE ILE A . n A 1 304 ARG 304 336 336 ARG ARG A . n A 1 305 LEU 305 337 337 LEU LEU A . n A 1 306 PHE 306 338 338 PHE PHE A . n A 1 307 GLN 307 339 339 GLN GLN A . n A 1 308 TYR 308 340 340 TYR TYR A . n A 1 309 ASP 309 341 341 ASP ASP A . n A 1 310 PRO 310 342 342 PRO PRO A . n A 1 311 ARG 311 343 343 ARG ARG A . n A 1 312 ASP 312 344 344 ASP ASP A . n A 1 313 TYR 313 345 345 TYR TYR A . n A 1 314 LYS 314 346 346 LYS LYS A . n A 1 315 LEU 315 347 347 LEU LEU A . n A 1 316 LEU 316 348 348 LEU LEU A . n A 1 317 ASP 317 349 349 ASP ASP A . n A 1 318 MET 318 350 350 MET MET A . n A 1 319 LEU 319 351 351 LEU LEU A . n A 1 320 GLN 320 352 352 GLN GLN A . n A 1 321 TYR 321 353 353 TYR TYR A . n A 1 322 TYR 322 354 354 TYR TYR A . n A 1 323 LEU 323 355 355 LEU LEU A . n A 1 324 ASN 324 356 356 ASN ASN A . n A 1 325 LEU 325 357 357 LEU LEU A . n A 1 326 THR 326 358 358 THR THR A . n A 1 327 GLU 327 359 359 GLU GLU A . n A 1 328 ALA 328 360 360 ALA ALA A . n A 1 329 ASN 329 361 361 ASN ASN A . n A 1 330 LEU 330 362 362 LEU LEU A . n A 1 331 LYS 331 363 363 LYS LYS A . n A 1 332 GLY 332 364 364 GLY GLY A . n A 1 333 GLU 333 365 365 GLU GLU A . n A 1 334 SER 334 366 366 SER SER A . n A 1 335 ILE 335 367 367 ILE ILE A . n A 1 336 TRP 336 368 368 TRP TRP A . n A 1 337 LYS 337 369 369 LYS LYS A . n A 1 338 LEU 338 370 370 LEU LEU A . n A 1 339 GLU 339 371 371 GLU GLU A . n A 1 340 TYR 340 372 372 TYR TYR A . n A 1 341 ILE 341 373 373 ILE ILE A . n A 1 342 LEU 342 374 374 LEU LEU A . n A 1 343 THR 343 375 375 THR THR A . n A 1 344 GLN 344 376 376 GLN GLN A . n A 1 345 THR 345 377 377 THR THR A . n A 1 346 TYR 346 378 378 TYR TYR A . n A 1 347 ASP 347 379 379 ASP ASP A . n A 1 348 ILE 348 380 380 ILE ILE A . n A 1 349 GLU 349 381 381 GLU GLU A . n A 1 350 ASP 350 382 382 ASP ASP A . n A 1 351 LEU 351 383 383 LEU LEU A . n A 1 352 GLN 352 384 384 GLN GLN A . n A 1 353 PRO 353 385 385 PRO PRO A . n A 1 354 GLU 354 386 386 GLU GLU A . n A 1 355 SER 355 387 387 SER SER A . n A 1 356 LEU 356 388 388 LEU LEU A . n A 1 357 TYR 357 389 389 TYR TYR A . n A 1 358 GLY 358 390 390 GLY GLY A . n A 1 359 LEU 359 391 391 LEU LEU A . n A 1 360 ALA 360 392 392 ALA ALA A . n A 1 361 LYS 361 393 393 LYS LYS A . n A 1 362 GLN 362 394 394 GLN GLN A . n A 1 363 PHE 363 395 395 PHE PHE A . n A 1 364 THR 364 396 396 THR THR A . n A 1 365 ILE 365 397 397 ILE ILE A . n A 1 366 LEU 366 398 398 LEU LEU A . n A 1 367 ASP 367 399 399 ASP ASP A . n A 1 368 SER 368 400 400 SER SER A . n A 1 369 LYS 369 401 401 LYS LYS A . n A 1 370 GLN 370 402 402 GLN GLN A . n A 1 371 PHE 371 403 403 PHE PHE A . n A 1 372 ILE 372 404 404 ILE ILE A . n A 1 373 LYS 373 405 405 LYS LYS A . n A 1 374 TYR 374 406 406 TYR TYR A . n A 1 375 TYR 375 407 407 TYR TYR A . n A 1 376 ASN 376 408 408 ASN ASN A . n A 1 377 TYR 377 409 409 TYR TYR A . n A 1 378 PHE 378 410 410 PHE PHE A . n A 1 379 PHE 379 411 411 PHE PHE A . n A 1 380 VAL 380 412 412 VAL VAL A . n A 1 381 SER 381 413 413 SER SER A . n A 1 382 TYR 382 414 414 TYR TYR A . n A 1 383 ASP 383 415 415 ASP ASP A . n A 1 384 SER 384 416 416 SER SER A . n A 1 385 SER 385 417 417 SER SER A . n A 1 386 VAL 386 418 418 VAL VAL A . n A 1 387 THR 387 419 419 THR THR A . n A 1 388 CYS 388 420 420 CYS CYS A . n A 1 389 ASP 389 421 421 ASP ASP A . n A 1 390 LYS 390 422 422 LYS LYS A . n A 1 391 THR 391 423 423 THR THR A . n A 1 392 CYS 392 424 424 CYS CYS A . n A 1 393 LYS 393 425 425 LYS LYS A . n A 1 394 ALA 394 426 426 ALA ALA A . n A 1 395 PHE 395 427 427 PHE PHE A . n A 1 396 GLN 396 428 428 GLN GLN A . n A 1 397 ILE 397 429 429 ILE ILE A . n A 1 398 CYS 398 430 430 CYS CYS A . n A 1 399 ALA 399 431 431 ALA ALA A . n A 1 400 ILE 400 432 432 ILE ILE A . n A 1 401 MET 401 433 433 MET MET A . n A 1 402 ASN 402 434 434 ASN ASN A . n A 1 403 LEU 403 435 435 LEU LEU A . n A 1 404 ASP 404 436 436 ASP ASP A . n A 1 405 ASN 405 437 437 ASN ASN A . n A 1 406 ILE 406 438 438 ILE ILE A . n A 1 407 SER 407 439 439 SER SER A . n A 1 408 TYR 408 440 440 TYR TYR A . n A 1 409 ALA 409 441 441 ALA ALA A . n A 1 410 ASP 410 442 442 ASP ASP A . n A 1 411 CYS 411 443 443 CYS CYS A . n A 1 412 LEU 412 444 444 LEU LEU A . n A 1 413 LYS 413 445 445 LYS LYS A . n A 1 414 GLN 414 446 446 GLN GLN A . n A 1 415 LEU 415 447 447 LEU LEU A . n A 1 416 TYR 416 448 448 TYR TYR A . n A 1 417 ILE 417 449 449 ILE ILE A . n A 1 418 LYS 418 450 450 LYS LYS A . n B 2 1 PRO 1 33 33 PRO PRO B . n B 2 2 PRO 2 34 34 PRO PRO B . n B 2 3 PRO 3 35 35 PRO PRO B . n B 2 4 ALA 4 36 36 ALA ALA B . n B 2 5 ILE 5 37 37 ILE ILE B . n B 2 6 GLY 6 38 38 GLY GLY B . n B 2 7 GLN 7 39 39 GLN GLN B . n B 2 8 PHE 8 40 40 PHE PHE B . n B 2 9 TRP 9 41 41 TRP TRP B . n B 2 10 HIS 10 42 42 HIS HIS B . n B 2 11 VAL 11 43 43 VAL VAL B . n B 2 12 THR 12 44 44 THR THR B . n B 2 13 ASP 13 45 45 ASP ASP B . n B 2 14 LEU 14 46 46 LEU LEU B . n B 2 15 HIS 15 47 47 HIS HIS B . n B 2 16 LEU 16 48 48 LEU LEU B . n B 2 17 ASP 17 49 49 ASP ASP B . n B 2 18 PRO 18 50 50 PRO PRO B . n B 2 19 THR 19 51 51 THR THR B . n B 2 20 TYR 20 52 52 TYR TYR B . n B 2 21 HIS 21 53 53 HIS HIS B . n B 2 22 ILE 22 54 54 ILE ILE B . n B 2 23 THR 23 55 55 THR THR B . n B 2 24 ASP 24 56 56 ASP ASP B . n B 2 25 ASP 25 57 57 ASP ASP B . n B 2 26 HIS 26 58 58 HIS HIS B . n B 2 27 THR 27 59 59 THR THR B . n B 2 28 LYS 28 60 60 LYS LYS B . n B 2 29 VAL 29 61 61 VAL VAL B . n B 2 30 CYS 30 62 62 CYS CYS B . n B 2 31 ALA 31 63 63 ALA ALA B . n B 2 32 SER 32 64 64 SER SER B . n B 2 33 SER 33 65 65 SER SER B . n B 2 34 LYS 34 66 66 LYS LYS B . n B 2 35 GLY 35 67 67 GLY GLY B . n B 2 36 ALA 36 68 68 ALA ALA B . n B 2 37 ASN 37 69 69 ASN ASN B . n B 2 38 ALA 38 70 70 ALA ALA B . n B 2 39 SER 39 71 71 SER SER B . n B 2 40 ASN 40 72 72 ASN ASN B . n B 2 41 PRO 41 73 73 PRO PRO B . n B 2 42 GLY 42 74 74 GLY GLY B . n B 2 43 PRO 43 75 75 PRO PRO B . n B 2 44 PHE 44 76 76 PHE PHE B . n B 2 45 GLY 45 77 77 GLY GLY B . n B 2 46 ASP 46 78 78 ASP ASP B . n B 2 47 VAL 47 79 79 VAL VAL B . n B 2 48 LEU 48 80 80 LEU LEU B . n B 2 49 CYS 49 81 81 CYS CYS B . n B 2 50 ASP 50 82 82 ASP ASP B . n B 2 51 SER 51 83 83 SER SER B . n B 2 52 PRO 52 84 84 PRO PRO B . n B 2 53 TYR 53 85 85 TYR TYR B . n B 2 54 GLN 54 86 86 GLN GLN B . n B 2 55 LEU 55 87 87 LEU LEU B . n B 2 56 ILE 56 88 88 ILE ILE B . n B 2 57 LEU 57 89 89 LEU LEU B . n B 2 58 SER 58 90 90 SER SER B . n B 2 59 ALA 59 91 91 ALA ALA B . n B 2 60 PHE 60 92 92 PHE PHE B . n B 2 61 ASP 61 93 93 ASP ASP B . n B 2 62 PHE 62 94 94 PHE PHE B . n B 2 63 ILE 63 95 95 ILE ILE B . n B 2 64 LYS 64 96 96 LYS LYS B . n B 2 65 ASN 65 97 97 ASN ASN B . n B 2 66 SER 66 98 98 SER SER B . n B 2 67 GLY 67 99 99 GLY GLY B . n B 2 68 GLN 68 100 100 GLN GLN B . n B 2 69 GLU 69 101 101 GLU GLU B . n B 2 70 ALA 70 102 102 ALA ALA B . n B 2 71 SER 71 103 103 SER SER B . n B 2 72 PHE 72 104 104 PHE PHE B . n B 2 73 MET 73 105 105 MET MET B . n B 2 74 ILE 74 106 106 ILE ILE B . n B 2 75 TRP 75 107 107 TRP TRP B . n B 2 76 THR 76 108 108 THR THR B . n B 2 77 GLY 77 109 109 GLY GLY B . n B 2 78 ASP 78 110 110 ASP ASP B . n B 2 79 SER 79 111 111 SER SER B . n B 2 80 PRO 80 112 112 PRO PRO B . n B 2 81 PRO 81 113 113 PRO PRO B . n B 2 82 HIS 82 114 114 HIS HIS B . n B 2 83 VAL 83 115 115 VAL VAL B . n B 2 84 PRO 84 116 116 PRO PRO B . n B 2 85 VAL 85 117 117 VAL VAL B . n B 2 86 PRO 86 118 118 PRO PRO B . n B 2 87 GLU 87 119 119 GLU GLU B . n B 2 88 LEU 88 120 120 LEU LEU B . n B 2 89 SER 89 121 121 SER SER B . n B 2 90 THR 90 122 122 THR THR B . n B 2 91 ASP 91 123 123 ASP ASP B . n B 2 92 THR 92 124 124 THR THR B . n B 2 93 VAL 93 125 125 VAL VAL B . n B 2 94 ILE 94 126 126 ILE ILE B . n B 2 95 ASN 95 127 127 ASN ASN B . n B 2 96 VAL 96 128 128 VAL VAL B . n B 2 97 ILE 97 129 129 ILE ILE B . n B 2 98 THR 98 130 130 THR THR B . n B 2 99 ASN 99 131 131 ASN ASN B . n B 2 100 MET 100 132 132 MET MET B . n B 2 101 THR 101 133 133 THR THR B . n B 2 102 THR 102 134 134 THR THR B . n B 2 103 THR 103 135 135 THR THR B . n B 2 104 ILE 104 136 136 ILE ILE B . n B 2 105 GLN 105 137 137 GLN GLN B . n B 2 106 SER 106 138 138 SER SER B . n B 2 107 LEU 107 139 139 LEU LEU B . n B 2 108 PHE 108 140 140 PHE PHE B . n B 2 109 PRO 109 141 141 PRO PRO B . n B 2 110 ASN 110 142 142 ASN ASN B . n B 2 111 LEU 111 143 143 LEU LEU B . n B 2 112 GLN 112 144 144 GLN GLN B . n B 2 113 VAL 113 145 145 VAL VAL B . n B 2 114 PHE 114 146 146 PHE PHE B . n B 2 115 PRO 115 147 147 PRO PRO B . n B 2 116 ALA 116 148 148 ALA ALA B . n B 2 117 LEU 117 149 149 LEU LEU B . n B 2 118 GLY 118 150 150 GLY GLY B . n B 2 119 ASN 119 151 151 ASN ASN B . n B 2 120 HIS 120 152 152 HIS HIS B . n B 2 121 ASP 121 153 153 ASP ASP B . n B 2 122 TYR 122 154 154 TYR TYR B . n B 2 123 TRP 123 155 155 TRP TRP B . n B 2 124 PRO 124 156 156 PRO PRO B . n B 2 125 GLN 125 157 157 GLN GLN B . n B 2 126 ASP 126 158 158 ASP ASP B . n B 2 127 GLN 127 159 159 GLN GLN B . n B 2 128 LEU 128 160 160 LEU LEU B . n B 2 129 PRO 129 161 161 PRO PRO B . n B 2 130 VAL 130 162 162 VAL VAL B . n B 2 131 VAL 131 163 163 VAL VAL B . n B 2 132 THR 132 164 164 THR THR B . n B 2 133 SER 133 165 165 SER SER B . n B 2 134 LYS 134 166 166 LYS LYS B . n B 2 135 VAL 135 167 167 VAL VAL B . n B 2 136 TYR 136 168 168 TYR TYR B . n B 2 137 ASN 137 169 169 ASN ASN B . n B 2 138 ALA 138 170 170 ALA ALA B . n B 2 139 VAL 139 171 171 VAL VAL B . n B 2 140 ALA 140 172 172 ALA ALA B . n B 2 141 ASN 141 173 173 ASN ASN B . n B 2 142 LEU 142 174 174 LEU LEU B . n B 2 143 TRP 143 175 175 TRP TRP B . n B 2 144 LYS 144 176 176 LYS LYS B . n B 2 145 PRO 145 177 177 PRO PRO B . n B 2 146 TRP 146 178 178 TRP TRP B . n B 2 147 LEU 147 179 179 LEU LEU B . n B 2 148 ASP 148 180 180 ASP ASP B . n B 2 149 GLU 149 181 181 GLU GLU B . n B 2 150 GLU 150 182 182 GLU GLU B . n B 2 151 ALA 151 183 183 ALA ALA B . n B 2 152 ILE 152 184 184 ILE ILE B . n B 2 153 SER 153 185 185 SER SER B . n B 2 154 THR 154 186 186 THR THR B . n B 2 155 LEU 155 187 187 LEU LEU B . n B 2 156 ARG 156 188 188 ARG ARG B . n B 2 157 LYS 157 189 189 LYS LYS B . n B 2 158 GLY 158 190 190 GLY GLY B . n B 2 159 GLY 159 191 191 GLY GLY B . n B 2 160 PHE 160 192 192 PHE PHE B . n B 2 161 TYR 161 193 193 TYR TYR B . n B 2 162 SER 162 194 194 SER SER B . n B 2 163 GLN 163 195 195 GLN GLN B . n B 2 164 LYS 164 196 196 LYS LYS B . n B 2 165 VAL 165 197 197 VAL VAL B . n B 2 166 THR 166 198 198 THR THR B . n B 2 167 THR 167 199 199 THR THR B . n B 2 168 ASN 168 200 200 ASN ASN B . n B 2 169 PRO 169 201 201 PRO PRO B . n B 2 170 ASN 170 202 202 ASN ASN B . n B 2 171 LEU 171 203 203 LEU LEU B . n B 2 172 ARG 172 204 204 ARG ARG B . n B 2 173 ILE 173 205 205 ILE ILE B . n B 2 174 ILE 174 206 206 ILE ILE B . n B 2 175 SER 175 207 207 SER SER B . n B 2 176 LEU 176 208 208 LEU LEU B . n B 2 177 ASN 177 209 209 ASN ASN B . n B 2 178 THR 178 210 210 THR THR B . n B 2 179 ASN 179 211 211 ASN ASN B . n B 2 180 LEU 180 212 212 LEU LEU B . n B 2 181 TYR 181 213 213 TYR TYR B . n B 2 182 TYR 182 214 214 TYR TYR B . n B 2 183 GLY 183 215 215 GLY GLY B . n B 2 184 PRO 184 216 216 PRO PRO B . n B 2 185 ASN 185 217 217 ASN ASN B . n B 2 186 ILE 186 218 218 ILE ILE B . n B 2 187 MET 187 219 219 MET MET B . n B 2 188 THR 188 220 220 THR THR B . n B 2 189 LEU 189 221 221 LEU LEU B . n B 2 190 ASN 190 222 222 ASN ASN B . n B 2 191 LYS 191 223 223 LYS LYS B . n B 2 192 THR 192 224 224 THR THR B . n B 2 193 ASP 193 225 225 ASP ASP B . n B 2 194 PRO 194 226 226 PRO PRO B . n B 2 195 ALA 195 227 227 ALA ALA B . n B 2 196 ASN 196 228 228 ASN ASN B . n B 2 197 GLN 197 229 229 GLN GLN B . n B 2 198 PHE 198 230 230 PHE PHE B . n B 2 199 GLU 199 231 231 GLU GLU B . n B 2 200 TRP 200 232 232 TRP TRP B . n B 2 201 LEU 201 233 233 LEU LEU B . n B 2 202 GLU 202 234 234 GLU GLU B . n B 2 203 SER 203 235 235 SER SER B . n B 2 204 THR 204 236 236 THR THR B . n B 2 205 LEU 205 237 237 LEU LEU B . n B 2 206 ASN 206 238 238 ASN ASN B . n B 2 207 ASN 207 239 239 ASN ASN B . n B 2 208 SER 208 240 240 SER SER B . n B 2 209 GLN 209 241 241 GLN GLN B . n B 2 210 GLN 210 242 242 GLN GLN B . n B 2 211 ASN 211 243 243 ASN ASN B . n B 2 212 LYS 212 244 244 LYS LYS B . n B 2 213 GLU 213 245 245 GLU GLU B . n B 2 214 LYS 214 246 246 LYS LYS B . n B 2 215 VAL 215 247 247 VAL VAL B . n B 2 216 TYR 216 248 248 TYR TYR B . n B 2 217 ILE 217 249 249 ILE ILE B . n B 2 218 ILE 218 250 250 ILE ILE B . n B 2 219 ALA 219 251 251 ALA ALA B . n B 2 220 HIS 220 252 252 HIS HIS B . n B 2 221 VAL 221 253 253 VAL VAL B . n B 2 222 PRO 222 254 254 PRO PRO B . n B 2 223 VAL 223 255 255 VAL VAL B . n B 2 224 GLY 224 256 256 GLY GLY B . n B 2 225 TYR 225 257 257 TYR TYR B . n B 2 226 LEU 226 258 258 LEU LEU B . n B 2 227 PRO 227 259 259 PRO PRO B . n B 2 228 SER 228 260 260 SER SER B . n B 2 229 SER 229 261 261 SER SER B . n B 2 230 GLN 230 262 262 GLN GLN B . n B 2 231 ASN 231 263 263 ASN ASN B . n B 2 232 ILE 232 264 264 ILE ILE B . n B 2 233 THR 233 265 265 THR THR B . n B 2 234 ALA 234 266 266 ALA ALA B . n B 2 235 MET 235 267 267 MET MET B . n B 2 236 ARG 236 268 268 ARG ARG B . n B 2 237 GLU 237 269 269 GLU GLU B . n B 2 238 TYR 238 270 270 TYR TYR B . n B 2 239 TYR 239 271 271 TYR TYR B . n B 2 240 ASN 240 272 272 ASN ASN B . n B 2 241 GLU 241 273 273 GLU GLU B . n B 2 242 LYS 242 274 274 LYS LYS B . n B 2 243 LEU 243 275 275 LEU LEU B . n B 2 244 ILE 244 276 276 ILE ILE B . n B 2 245 ASP 245 277 277 ASP ASP B . n B 2 246 ILE 246 278 278 ILE ILE B . n B 2 247 PHE 247 279 279 PHE PHE B . n B 2 248 GLN 248 280 280 GLN GLN B . n B 2 249 LYS 249 281 281 LYS LYS B . n B 2 250 TYR 250 282 282 TYR TYR B . n B 2 251 SER 251 283 283 SER SER B . n B 2 252 ASP 252 284 284 ASP ASP B . n B 2 253 VAL 253 285 285 VAL VAL B . n B 2 254 ILE 254 286 286 ILE ILE B . n B 2 255 ALA 255 287 287 ALA ALA B . n B 2 256 GLY 256 288 288 GLY GLY B . n B 2 257 GLN 257 289 289 GLN GLN B . n B 2 258 PHE 258 290 290 PHE PHE B . n B 2 259 TYR 259 291 291 TYR TYR B . n B 2 260 GLY 260 292 292 GLY GLY B . n B 2 261 HIS 261 293 293 HIS HIS B . n B 2 262 THR 262 294 294 THR THR B . n B 2 263 HIS 263 295 295 HIS HIS B . n B 2 264 ARG 264 296 296 ARG ARG B . n B 2 265 ASP 265 297 297 ASP ASP B . n B 2 266 SER 266 298 298 SER SER B . n B 2 267 ILE 267 299 299 ILE ILE B . n B 2 268 MET 268 300 300 MET MET B . n B 2 269 VAL 269 301 301 VAL VAL B . n B 2 270 LEU 270 302 302 LEU LEU B . n B 2 271 SER 271 303 303 SER SER B . n B 2 272 ASP 272 304 304 ASP ASP B . n B 2 273 LYS 273 305 305 LYS LYS B . n B 2 274 LYS 274 306 306 LYS LYS B . n B 2 275 GLY 275 307 307 GLY GLY B . n B 2 276 SER 276 308 308 SER SER B . n B 2 277 PRO 277 309 309 PRO PRO B . n B 2 278 VAL 278 310 310 VAL VAL B . n B 2 279 ASN 279 311 311 ASN ASN B . n B 2 280 SER 280 312 312 SER SER B . n B 2 281 LEU 281 313 313 LEU LEU B . n B 2 282 PHE 282 314 314 PHE PHE B . n B 2 283 VAL 283 315 315 VAL VAL B . n B 2 284 ALA 284 316 316 ALA ALA B . n B 2 285 PRO 285 317 317 PRO PRO B . n B 2 286 ALA 286 318 318 ALA ALA B . n B 2 287 VAL 287 319 319 VAL VAL B . n B 2 288 THR 288 320 320 THR THR B . n B 2 289 PRO 289 321 321 PRO PRO B . n B 2 290 VAL 290 322 322 VAL VAL B . n B 2 291 LYS 291 323 323 LYS LYS B . n B 2 292 SER 292 324 324 SER SER B . n B 2 293 VAL 293 325 325 VAL VAL B . n B 2 294 LEU 294 326 326 LEU LEU B . n B 2 295 GLU 295 327 327 GLU GLU B . n B 2 296 LYS 296 328 328 LYS LYS B . n B 2 297 GLN 297 329 329 GLN GLN B . n B 2 298 THR 298 330 330 THR THR B . n B 2 299 ASN 299 331 331 ASN ASN B . n B 2 300 ASN 300 332 332 ASN ASN B . n B 2 301 PRO 301 333 333 PRO PRO B . n B 2 302 GLY 302 334 334 GLY GLY B . n B 2 303 ILE 303 335 335 ILE ILE B . n B 2 304 ARG 304 336 336 ARG ARG B . n B 2 305 LEU 305 337 337 LEU LEU B . n B 2 306 PHE 306 338 338 PHE PHE B . n B 2 307 GLN 307 339 339 GLN GLN B . n B 2 308 TYR 308 340 340 TYR TYR B . n B 2 309 ASP 309 341 341 ASP ASP B . n B 2 310 PRO 310 342 342 PRO PRO B . n B 2 311 ARG 311 343 343 ARG ARG B . n B 2 312 ASP 312 344 344 ASP ASP B . n B 2 313 TYR 313 345 345 TYR TYR B . n B 2 314 LYS 314 346 346 LYS LYS B . n B 2 315 LEU 315 347 347 LEU LEU B . n B 2 316 LEU 316 348 348 LEU LEU B . n B 2 317 ASP 317 349 349 ASP ASP B . n B 2 318 MET 318 350 350 MET MET B . n B 2 319 LEU 319 351 351 LEU LEU B . n B 2 320 GLN 320 352 352 GLN GLN B . n B 2 321 TYR 321 353 353 TYR TYR B . n B 2 322 TYR 322 354 354 TYR TYR B . n B 2 323 LEU 323 355 355 LEU LEU B . n B 2 324 ASN 324 356 356 ASN ASN B . n B 2 325 LEU 325 357 357 LEU LEU B . n B 2 326 THR 326 358 358 THR THR B . n B 2 327 GLU 327 359 359 GLU GLU B . n B 2 328 ALA 328 360 360 ALA ALA B . n B 2 329 ASN 329 361 361 ASN ASN B . n B 2 330 LEU 330 362 362 LEU LEU B . n B 2 331 LYS 331 363 363 LYS LYS B . n B 2 332 GLY 332 364 364 GLY GLY B . n B 2 333 GLU 333 365 365 GLU GLU B . n B 2 334 SER 334 366 366 SER SER B . n B 2 335 ILE 335 367 367 ILE ILE B . n B 2 336 TRP 336 368 368 TRP TRP B . n B 2 337 LYS 337 369 369 LYS LYS B . n B 2 338 LEU 338 370 370 LEU LEU B . n B 2 339 GLU 339 371 371 GLU GLU B . n B 2 340 TYR 340 372 372 TYR TYR B . n B 2 341 ILE 341 373 373 ILE ILE B . n B 2 342 LEU 342 374 374 LEU LEU B . n B 2 343 THR 343 375 375 THR THR B . n B 2 344 GLN 344 376 376 GLN GLN B . n B 2 345 THR 345 377 377 THR THR B . n B 2 346 TYR 346 378 378 TYR TYR B . n B 2 347 ASP 347 379 379 ASP ASP B . n B 2 348 ILE 348 380 380 ILE ILE B . n B 2 349 GLU 349 381 381 GLU GLU B . n B 2 350 ASP 350 382 382 ASP ASP B . n B 2 351 LEU 351 383 383 LEU LEU B . n B 2 352 GLN 352 384 384 GLN GLN B . n B 2 353 PRO 353 385 385 PRO PRO B . n B 2 354 GLU 354 386 386 GLU GLU B . n B 2 355 SER 355 387 387 SER SER B . n B 2 356 LEU 356 388 388 LEU LEU B . n B 2 357 TYR 357 389 389 TYR TYR B . n B 2 358 GLY 358 390 390 GLY GLY B . n B 2 359 LEU 359 391 391 LEU LEU B . n B 2 360 ALA 360 392 392 ALA ALA B . n B 2 361 LYS 361 393 393 LYS LYS B . n B 2 362 GLN 362 394 394 GLN GLN B . n B 2 363 PHE 363 395 395 PHE PHE B . n B 2 364 THR 364 396 396 THR THR B . n B 2 365 ILE 365 397 397 ILE ILE B . n B 2 366 LEU 366 398 398 LEU LEU B . n B 2 367 ASP 367 399 399 ASP ASP B . n B 2 368 SER 368 400 400 SER SER B . n B 2 369 LYS 369 401 401 LYS LYS B . n B 2 370 GLN 370 402 402 GLN GLN B . n B 2 371 PHE 371 403 403 PHE PHE B . n B 2 372 ILE 372 404 404 ILE ILE B . n B 2 373 LYS 373 405 405 LYS LYS B . n B 2 374 TYR 374 406 406 TYR TYR B . n B 2 375 TYR 375 407 407 TYR TYR B . n B 2 376 ASN 376 408 408 ASN ASN B . n B 2 377 TYR 377 409 409 TYR TYR B . n B 2 378 PHE 378 410 410 PHE PHE B . n B 2 379 PHE 379 411 411 PHE PHE B . n B 2 380 VAL 380 412 412 VAL VAL B . n B 2 381 SER 381 413 413 SER SER B . n B 2 382 TYR 382 414 414 TYR TYR B . n B 2 383 ASP 383 415 415 ASP ASP B . n B 2 384 SER 384 416 416 SER SER B . n B 2 385 SER 385 417 417 SER SER B . n B 2 386 VAL 386 418 418 VAL VAL B . n B 2 387 THR 387 419 419 THR THR B . n B 2 388 CYS 388 420 420 CYS CYS B . n B 2 389 ASP 389 421 421 ASP ASP B . n B 2 390 LYS 390 422 422 LYS LYS B . n B 2 391 THR 391 423 423 THR THR B . n B 2 392 CYS 392 424 424 CYS CYS B . n B 2 393 LYS 393 425 425 LYS LYS B . n B 2 394 ALA 394 426 426 ALA ALA B . n B 2 395 PHE 395 427 427 PHE PHE B . n B 2 396 GLN 396 428 428 GLN GLN B . n B 2 397 ILE 397 429 429 ILE ILE B . n B 2 398 CYS 398 430 430 CYS CYS B . n B 2 399 ALA 399 431 431 ALA ALA B . n B 2 400 ILE 400 432 432 ILE ILE B . n B 2 401 MET 401 433 433 MET MET B . n B 2 402 ASN 402 434 434 ASN ASN B . n B 2 403 LEU 403 435 435 LEU LEU B . n B 2 404 ASP 404 436 436 ASP ASP B . n B 2 405 ASN 405 437 437 ASN ASN B . n B 2 406 ILE 406 438 438 ILE ILE B . n B 2 407 SER 407 439 439 SER SER B . n B 2 408 TYR 408 440 440 TYR TYR B . n B 2 409 ALA 409 441 441 ALA ALA B . n B 2 410 ASP 410 442 442 ASP ASP B . n B 2 411 CYS 411 443 443 CYS CYS B . n B 2 412 LEU 412 444 444 LEU LEU B . n B 2 413 LYS 413 445 445 LYS LYS B . n B 2 414 GLN 414 446 446 GLN GLN B . n B 2 415 LEU 415 447 447 LEU LEU B . n C 2 1 PRO 1 33 33 PRO PRO C . n C 2 2 PRO 2 34 34 PRO PRO C . n C 2 3 PRO 3 35 35 PRO PRO C . n C 2 4 ALA 4 36 36 ALA ALA C . n C 2 5 ILE 5 37 37 ILE ILE C . n C 2 6 GLY 6 38 38 GLY GLY C . n C 2 7 GLN 7 39 39 GLN GLN C . n C 2 8 PHE 8 40 40 PHE PHE C . n C 2 9 TRP 9 41 41 TRP TRP C . n C 2 10 HIS 10 42 42 HIS HIS C . n C 2 11 VAL 11 43 43 VAL VAL C . n C 2 12 THR 12 44 44 THR THR C . n C 2 13 ASP 13 45 45 ASP ASP C . n C 2 14 LEU 14 46 46 LEU LEU C . n C 2 15 HIS 15 47 47 HIS HIS C . n C 2 16 LEU 16 48 48 LEU LEU C . n C 2 17 ASP 17 49 49 ASP ASP C . n C 2 18 PRO 18 50 50 PRO PRO C . n C 2 19 THR 19 51 51 THR THR C . n C 2 20 TYR 20 52 52 TYR TYR C . n C 2 21 HIS 21 53 53 HIS HIS C . n C 2 22 ILE 22 54 54 ILE ILE C . n C 2 23 THR 23 55 55 THR THR C . n C 2 24 ASP 24 56 56 ASP ASP C . n C 2 25 ASP 25 57 57 ASP ASP C . n C 2 26 HIS 26 58 58 HIS HIS C . n C 2 27 THR 27 59 59 THR THR C . n C 2 28 LYS 28 60 60 LYS LYS C . n C 2 29 VAL 29 61 61 VAL VAL C . n C 2 30 CYS 30 62 62 CYS CYS C . n C 2 31 ALA 31 63 63 ALA ALA C . n C 2 32 SER 32 64 64 SER SER C . n C 2 33 SER 33 65 65 SER SER C . n C 2 34 LYS 34 66 66 LYS LYS C . n C 2 35 GLY 35 67 67 GLY GLY C . n C 2 36 ALA 36 68 68 ALA ALA C . n C 2 37 ASN 37 69 69 ASN ASN C . n C 2 38 ALA 38 70 70 ALA ALA C . n C 2 39 SER 39 71 71 SER SER C . n C 2 40 ASN 40 72 72 ASN ASN C . n C 2 41 PRO 41 73 73 PRO PRO C . n C 2 42 GLY 42 74 74 GLY GLY C . n C 2 43 PRO 43 75 75 PRO PRO C . n C 2 44 PHE 44 76 76 PHE PHE C . n C 2 45 GLY 45 77 77 GLY GLY C . n C 2 46 ASP 46 78 78 ASP ASP C . n C 2 47 VAL 47 79 79 VAL VAL C . n C 2 48 LEU 48 80 80 LEU LEU C . n C 2 49 CYS 49 81 81 CYS CYS C . n C 2 50 ASP 50 82 82 ASP ASP C . n C 2 51 SER 51 83 83 SER SER C . n C 2 52 PRO 52 84 84 PRO PRO C . n C 2 53 TYR 53 85 85 TYR TYR C . n C 2 54 GLN 54 86 86 GLN GLN C . n C 2 55 LEU 55 87 87 LEU LEU C . n C 2 56 ILE 56 88 88 ILE ILE C . n C 2 57 LEU 57 89 89 LEU LEU C . n C 2 58 SER 58 90 90 SER SER C . n C 2 59 ALA 59 91 91 ALA ALA C . n C 2 60 PHE 60 92 92 PHE PHE C . n C 2 61 ASP 61 93 93 ASP ASP C . n C 2 62 PHE 62 94 94 PHE PHE C . n C 2 63 ILE 63 95 95 ILE ILE C . n C 2 64 LYS 64 96 96 LYS LYS C . n C 2 65 ASN 65 97 97 ASN ASN C . n C 2 66 SER 66 98 98 SER SER C . n C 2 67 GLY 67 99 99 GLY GLY C . n C 2 68 GLN 68 100 100 GLN GLN C . n C 2 69 GLU 69 101 101 GLU GLU C . n C 2 70 ALA 70 102 102 ALA ALA C . n C 2 71 SER 71 103 103 SER SER C . n C 2 72 PHE 72 104 104 PHE PHE C . n C 2 73 MET 73 105 105 MET MET C . n C 2 74 ILE 74 106 106 ILE ILE C . n C 2 75 TRP 75 107 107 TRP TRP C . n C 2 76 THR 76 108 108 THR THR C . n C 2 77 GLY 77 109 109 GLY GLY C . n C 2 78 ASP 78 110 110 ASP ASP C . n C 2 79 SER 79 111 111 SER SER C . n C 2 80 PRO 80 112 112 PRO PRO C . n C 2 81 PRO 81 113 113 PRO PRO C . n C 2 82 HIS 82 114 114 HIS HIS C . n C 2 83 VAL 83 115 115 VAL VAL C . n C 2 84 PRO 84 116 116 PRO PRO C . n C 2 85 VAL 85 117 117 VAL VAL C . n C 2 86 PRO 86 118 118 PRO PRO C . n C 2 87 GLU 87 119 119 GLU GLU C . n C 2 88 LEU 88 120 120 LEU LEU C . n C 2 89 SER 89 121 121 SER SER C . n C 2 90 THR 90 122 122 THR THR C . n C 2 91 ASP 91 123 123 ASP ASP C . n C 2 92 THR 92 124 124 THR THR C . n C 2 93 VAL 93 125 125 VAL VAL C . n C 2 94 ILE 94 126 126 ILE ILE C . n C 2 95 ASN 95 127 127 ASN ASN C . n C 2 96 VAL 96 128 128 VAL VAL C . n C 2 97 ILE 97 129 129 ILE ILE C . n C 2 98 THR 98 130 130 THR THR C . n C 2 99 ASN 99 131 131 ASN ASN C . n C 2 100 MET 100 132 132 MET MET C . n C 2 101 THR 101 133 133 THR THR C . n C 2 102 THR 102 134 134 THR THR C . n C 2 103 THR 103 135 135 THR THR C . n C 2 104 ILE 104 136 136 ILE ILE C . n C 2 105 GLN 105 137 137 GLN GLN C . n C 2 106 SER 106 138 138 SER SER C . n C 2 107 LEU 107 139 139 LEU LEU C . n C 2 108 PHE 108 140 140 PHE PHE C . n C 2 109 PRO 109 141 141 PRO PRO C . n C 2 110 ASN 110 142 142 ASN ASN C . n C 2 111 LEU 111 143 143 LEU LEU C . n C 2 112 GLN 112 144 144 GLN GLN C . n C 2 113 VAL 113 145 145 VAL VAL C . n C 2 114 PHE 114 146 146 PHE PHE C . n C 2 115 PRO 115 147 147 PRO PRO C . n C 2 116 ALA 116 148 148 ALA ALA C . n C 2 117 LEU 117 149 149 LEU LEU C . n C 2 118 GLY 118 150 150 GLY GLY C . n C 2 119 ASN 119 151 151 ASN ASN C . n C 2 120 HIS 120 152 152 HIS HIS C . n C 2 121 ASP 121 153 153 ASP ASP C . n C 2 122 TYR 122 154 154 TYR TYR C . n C 2 123 TRP 123 155 155 TRP TRP C . n C 2 124 PRO 124 156 156 PRO PRO C . n C 2 125 GLN 125 157 157 GLN GLN C . n C 2 126 ASP 126 158 158 ASP ASP C . n C 2 127 GLN 127 159 159 GLN GLN C . n C 2 128 LEU 128 160 160 LEU LEU C . n C 2 129 PRO 129 161 161 PRO PRO C . n C 2 130 VAL 130 162 162 VAL VAL C . n C 2 131 VAL 131 163 163 VAL VAL C . n C 2 132 THR 132 164 164 THR THR C . n C 2 133 SER 133 165 165 SER SER C . n C 2 134 LYS 134 166 166 LYS LYS C . n C 2 135 VAL 135 167 167 VAL VAL C . n C 2 136 TYR 136 168 168 TYR TYR C . n C 2 137 ASN 137 169 169 ASN ASN C . n C 2 138 ALA 138 170 170 ALA ALA C . n C 2 139 VAL 139 171 171 VAL VAL C . n C 2 140 ALA 140 172 172 ALA ALA C . n C 2 141 ASN 141 173 173 ASN ASN C . n C 2 142 LEU 142 174 174 LEU LEU C . n C 2 143 TRP 143 175 175 TRP TRP C . n C 2 144 LYS 144 176 176 LYS LYS C . n C 2 145 PRO 145 177 177 PRO PRO C . n C 2 146 TRP 146 178 178 TRP TRP C . n C 2 147 LEU 147 179 179 LEU LEU C . n C 2 148 ASP 148 180 180 ASP ASP C . n C 2 149 GLU 149 181 181 GLU GLU C . n C 2 150 GLU 150 182 182 GLU GLU C . n C 2 151 ALA 151 183 183 ALA ALA C . n C 2 152 ILE 152 184 184 ILE ILE C . n C 2 153 SER 153 185 185 SER SER C . n C 2 154 THR 154 186 186 THR THR C . n C 2 155 LEU 155 187 187 LEU LEU C . n C 2 156 ARG 156 188 188 ARG ARG C . n C 2 157 LYS 157 189 189 LYS LYS C . n C 2 158 GLY 158 190 190 GLY GLY C . n C 2 159 GLY 159 191 191 GLY GLY C . n C 2 160 PHE 160 192 192 PHE PHE C . n C 2 161 TYR 161 193 193 TYR TYR C . n C 2 162 SER 162 194 194 SER SER C . n C 2 163 GLN 163 195 195 GLN GLN C . n C 2 164 LYS 164 196 196 LYS LYS C . n C 2 165 VAL 165 197 197 VAL VAL C . n C 2 166 THR 166 198 198 THR THR C . n C 2 167 THR 167 199 199 THR THR C . n C 2 168 ASN 168 200 200 ASN ASN C . n C 2 169 PRO 169 201 201 PRO PRO C . n C 2 170 ASN 170 202 202 ASN ASN C . n C 2 171 LEU 171 203 203 LEU LEU C . n C 2 172 ARG 172 204 204 ARG ARG C . n C 2 173 ILE 173 205 205 ILE ILE C . n C 2 174 ILE 174 206 206 ILE ILE C . n C 2 175 SER 175 207 207 SER SER C . n C 2 176 LEU 176 208 208 LEU LEU C . n C 2 177 ASN 177 209 209 ASN ASN C . n C 2 178 THR 178 210 210 THR THR C . n C 2 179 ASN 179 211 211 ASN ASN C . n C 2 180 LEU 180 212 212 LEU LEU C . n C 2 181 TYR 181 213 213 TYR TYR C . n C 2 182 TYR 182 214 214 TYR TYR C . n C 2 183 GLY 183 215 215 GLY GLY C . n C 2 184 PRO 184 216 216 PRO PRO C . n C 2 185 ASN 185 217 217 ASN ASN C . n C 2 186 ILE 186 218 218 ILE ILE C . n C 2 187 MET 187 219 219 MET MET C . n C 2 188 THR 188 220 220 THR THR C . n C 2 189 LEU 189 221 221 LEU LEU C . n C 2 190 ASN 190 222 222 ASN ASN C . n C 2 191 LYS 191 223 223 LYS LYS C . n C 2 192 THR 192 224 224 THR THR C . n C 2 193 ASP 193 225 225 ASP ASP C . n C 2 194 PRO 194 226 226 PRO PRO C . n C 2 195 ALA 195 227 227 ALA ALA C . n C 2 196 ASN 196 228 228 ASN ASN C . n C 2 197 GLN 197 229 229 GLN GLN C . n C 2 198 PHE 198 230 230 PHE PHE C . n C 2 199 GLU 199 231 231 GLU GLU C . n C 2 200 TRP 200 232 232 TRP TRP C . n C 2 201 LEU 201 233 233 LEU LEU C . n C 2 202 GLU 202 234 234 GLU GLU C . n C 2 203 SER 203 235 235 SER SER C . n C 2 204 THR 204 236 236 THR THR C . n C 2 205 LEU 205 237 237 LEU LEU C . n C 2 206 ASN 206 238 238 ASN ASN C . n C 2 207 ASN 207 239 239 ASN ASN C . n C 2 208 SER 208 240 240 SER SER C . n C 2 209 GLN 209 241 241 GLN GLN C . n C 2 210 GLN 210 242 242 GLN GLN C . n C 2 211 ASN 211 243 243 ASN ASN C . n C 2 212 LYS 212 244 244 LYS LYS C . n C 2 213 GLU 213 245 245 GLU GLU C . n C 2 214 LYS 214 246 246 LYS LYS C . n C 2 215 VAL 215 247 247 VAL VAL C . n C 2 216 TYR 216 248 248 TYR TYR C . n C 2 217 ILE 217 249 249 ILE ILE C . n C 2 218 ILE 218 250 250 ILE ILE C . n C 2 219 ALA 219 251 251 ALA ALA C . n C 2 220 HIS 220 252 252 HIS HIS C . n C 2 221 VAL 221 253 253 VAL VAL C . n C 2 222 PRO 222 254 254 PRO PRO C . n C 2 223 VAL 223 255 255 VAL VAL C . n C 2 224 GLY 224 256 256 GLY GLY C . n C 2 225 TYR 225 257 257 TYR TYR C . n C 2 226 LEU 226 258 258 LEU LEU C . n C 2 227 PRO 227 259 259 PRO PRO C . n C 2 228 SER 228 260 260 SER SER C . n C 2 229 SER 229 261 261 SER SER C . n C 2 230 GLN 230 262 262 GLN GLN C . n C 2 231 ASN 231 263 263 ASN ASN C . n C 2 232 ILE 232 264 264 ILE ILE C . n C 2 233 THR 233 265 265 THR THR C . n C 2 234 ALA 234 266 266 ALA ALA C . n C 2 235 MET 235 267 267 MET MET C . n C 2 236 ARG 236 268 268 ARG ARG C . n C 2 237 GLU 237 269 269 GLU GLU C . n C 2 238 TYR 238 270 270 TYR TYR C . n C 2 239 TYR 239 271 271 TYR TYR C . n C 2 240 ASN 240 272 272 ASN ASN C . n C 2 241 GLU 241 273 273 GLU GLU C . n C 2 242 LYS 242 274 274 LYS LYS C . n C 2 243 LEU 243 275 275 LEU LEU C . n C 2 244 ILE 244 276 276 ILE ILE C . n C 2 245 ASP 245 277 277 ASP ASP C . n C 2 246 ILE 246 278 278 ILE ILE C . n C 2 247 PHE 247 279 279 PHE PHE C . n C 2 248 GLN 248 280 280 GLN GLN C . n C 2 249 LYS 249 281 281 LYS LYS C . n C 2 250 TYR 250 282 282 TYR TYR C . n C 2 251 SER 251 283 283 SER SER C . n C 2 252 ASP 252 284 284 ASP ASP C . n C 2 253 VAL 253 285 285 VAL VAL C . n C 2 254 ILE 254 286 286 ILE ILE C . n C 2 255 ALA 255 287 287 ALA ALA C . n C 2 256 GLY 256 288 288 GLY GLY C . n C 2 257 GLN 257 289 289 GLN GLN C . n C 2 258 PHE 258 290 290 PHE PHE C . n C 2 259 TYR 259 291 291 TYR TYR C . n C 2 260 GLY 260 292 292 GLY GLY C . n C 2 261 HIS 261 293 293 HIS HIS C . n C 2 262 THR 262 294 294 THR THR C . n C 2 263 HIS 263 295 295 HIS HIS C . n C 2 264 ARG 264 296 296 ARG ARG C . n C 2 265 ASP 265 297 297 ASP ASP C . n C 2 266 SER 266 298 298 SER SER C . n C 2 267 ILE 267 299 299 ILE ILE C . n C 2 268 MET 268 300 300 MET MET C . n C 2 269 VAL 269 301 301 VAL VAL C . n C 2 270 LEU 270 302 302 LEU LEU C . n C 2 271 SER 271 303 303 SER SER C . n C 2 272 ASP 272 304 304 ASP ASP C . n C 2 273 LYS 273 305 305 LYS LYS C . n C 2 274 LYS 274 306 306 LYS LYS C . n C 2 275 GLY 275 307 307 GLY GLY C . n C 2 276 SER 276 308 308 SER SER C . n C 2 277 PRO 277 309 309 PRO PRO C . n C 2 278 VAL 278 310 310 VAL VAL C . n C 2 279 ASN 279 311 311 ASN ASN C . n C 2 280 SER 280 312 312 SER SER C . n C 2 281 LEU 281 313 313 LEU LEU C . n C 2 282 PHE 282 314 314 PHE PHE C . n C 2 283 VAL 283 315 315 VAL VAL C . n C 2 284 ALA 284 316 316 ALA ALA C . n C 2 285 PRO 285 317 317 PRO PRO C . n C 2 286 ALA 286 318 318 ALA ALA C . n C 2 287 VAL 287 319 319 VAL VAL C . n C 2 288 THR 288 320 320 THR THR C . n C 2 289 PRO 289 321 321 PRO PRO C . n C 2 290 VAL 290 322 322 VAL VAL C . n C 2 291 LYS 291 323 323 LYS LYS C . n C 2 292 SER 292 324 324 SER SER C . n C 2 293 VAL 293 325 325 VAL VAL C . n C 2 294 LEU 294 326 326 LEU LEU C . n C 2 295 GLU 295 327 327 GLU GLU C . n C 2 296 LYS 296 328 328 LYS LYS C . n C 2 297 GLN 297 329 329 GLN GLN C . n C 2 298 THR 298 330 330 THR THR C . n C 2 299 ASN 299 331 331 ASN ASN C . n C 2 300 ASN 300 332 332 ASN ASN C . n C 2 301 PRO 301 333 333 PRO PRO C . n C 2 302 GLY 302 334 334 GLY GLY C . n C 2 303 ILE 303 335 335 ILE ILE C . n C 2 304 ARG 304 336 336 ARG ARG C . n C 2 305 LEU 305 337 337 LEU LEU C . n C 2 306 PHE 306 338 338 PHE PHE C . n C 2 307 GLN 307 339 339 GLN GLN C . n C 2 308 TYR 308 340 340 TYR TYR C . n C 2 309 ASP 309 341 341 ASP ASP C . n C 2 310 PRO 310 342 342 PRO PRO C . n C 2 311 ARG 311 343 343 ARG ARG C . n C 2 312 ASP 312 344 344 ASP ASP C . n C 2 313 TYR 313 345 345 TYR TYR C . n C 2 314 LYS 314 346 346 LYS LYS C . n C 2 315 LEU 315 347 347 LEU LEU C . n C 2 316 LEU 316 348 348 LEU LEU C . n C 2 317 ASP 317 349 349 ASP ASP C . n C 2 318 MET 318 350 350 MET MET C . n C 2 319 LEU 319 351 351 LEU LEU C . n C 2 320 GLN 320 352 352 GLN GLN C . n C 2 321 TYR 321 353 353 TYR TYR C . n C 2 322 TYR 322 354 354 TYR TYR C . n C 2 323 LEU 323 355 355 LEU LEU C . n C 2 324 ASN 324 356 356 ASN ASN C . n C 2 325 LEU 325 357 357 LEU LEU C . n C 2 326 THR 326 358 358 THR THR C . n C 2 327 GLU 327 359 359 GLU GLU C . n C 2 328 ALA 328 360 360 ALA ALA C . n C 2 329 ASN 329 361 361 ASN ASN C . n C 2 330 LEU 330 362 362 LEU LEU C . n C 2 331 LYS 331 363 363 LYS LYS C . n C 2 332 GLY 332 364 364 GLY GLY C . n C 2 333 GLU 333 365 365 GLU GLU C . n C 2 334 SER 334 366 366 SER SER C . n C 2 335 ILE 335 367 367 ILE ILE C . n C 2 336 TRP 336 368 368 TRP TRP C . n C 2 337 LYS 337 369 369 LYS LYS C . n C 2 338 LEU 338 370 370 LEU LEU C . n C 2 339 GLU 339 371 371 GLU GLU C . n C 2 340 TYR 340 372 372 TYR TYR C . n C 2 341 ILE 341 373 373 ILE ILE C . n C 2 342 LEU 342 374 374 LEU LEU C . n C 2 343 THR 343 375 375 THR THR C . n C 2 344 GLN 344 376 376 GLN GLN C . n C 2 345 THR 345 377 377 THR THR C . n C 2 346 TYR 346 378 378 TYR TYR C . n C 2 347 ASP 347 379 379 ASP ASP C . n C 2 348 ILE 348 380 380 ILE ILE C . n C 2 349 GLU 349 381 381 GLU GLU C . n C 2 350 ASP 350 382 382 ASP ASP C . n C 2 351 LEU 351 383 383 LEU LEU C . n C 2 352 GLN 352 384 384 GLN GLN C . n C 2 353 PRO 353 385 385 PRO PRO C . n C 2 354 GLU 354 386 386 GLU GLU C . n C 2 355 SER 355 387 387 SER SER C . n C 2 356 LEU 356 388 388 LEU LEU C . n C 2 357 TYR 357 389 389 TYR TYR C . n C 2 358 GLY 358 390 390 GLY GLY C . n C 2 359 LEU 359 391 391 LEU LEU C . n C 2 360 ALA 360 392 392 ALA ALA C . n C 2 361 LYS 361 393 393 LYS LYS C . n C 2 362 GLN 362 394 394 GLN GLN C . n C 2 363 PHE 363 395 395 PHE PHE C . n C 2 364 THR 364 396 396 THR THR C . n C 2 365 ILE 365 397 397 ILE ILE C . n C 2 366 LEU 366 398 398 LEU LEU C . n C 2 367 ASP 367 399 399 ASP ASP C . n C 2 368 SER 368 400 400 SER SER C . n C 2 369 LYS 369 401 401 LYS LYS C . n C 2 370 GLN 370 402 402 GLN GLN C . n C 2 371 PHE 371 403 403 PHE PHE C . n C 2 372 ILE 372 404 404 ILE ILE C . n C 2 373 LYS 373 405 405 LYS LYS C . n C 2 374 TYR 374 406 406 TYR TYR C . n C 2 375 TYR 375 407 407 TYR TYR C . n C 2 376 ASN 376 408 408 ASN ASN C . n C 2 377 TYR 377 409 409 TYR TYR C . n C 2 378 PHE 378 410 410 PHE PHE C . n C 2 379 PHE 379 411 411 PHE PHE C . n C 2 380 VAL 380 412 412 VAL VAL C . n C 2 381 SER 381 413 413 SER SER C . n C 2 382 TYR 382 414 414 TYR TYR C . n C 2 383 ASP 383 415 415 ASP ASP C . n C 2 384 SER 384 416 416 SER SER C . n C 2 385 SER 385 417 417 SER SER C . n C 2 386 VAL 386 418 418 VAL VAL C . n C 2 387 THR 387 419 419 THR THR C . n C 2 388 CYS 388 420 420 CYS CYS C . n C 2 389 ASP 389 421 421 ASP ASP C . n C 2 390 LYS 390 422 422 LYS LYS C . n C 2 391 THR 391 423 423 THR THR C . n C 2 392 CYS 392 424 424 CYS CYS C . n C 2 393 LYS 393 425 425 LYS LYS C . n C 2 394 ALA 394 426 426 ALA ALA C . n C 2 395 PHE 395 427 427 PHE PHE C . n C 2 396 GLN 396 428 428 GLN GLN C . n C 2 397 ILE 397 429 429 ILE ILE C . n C 2 398 CYS 398 430 430 CYS CYS C . n C 2 399 ALA 399 431 431 ALA ALA C . n C 2 400 ILE 400 432 432 ILE ILE C . n C 2 401 MET 401 433 433 MET MET C . n C 2 402 ASN 402 434 434 ASN ASN C . n C 2 403 LEU 403 435 435 LEU LEU C . n C 2 404 ASP 404 436 436 ASP ASP C . n C 2 405 ASN 405 437 437 ASN ASN C . n C 2 406 ILE 406 438 438 ILE ILE C . n C 2 407 SER 407 439 439 SER SER C . n C 2 408 TYR 408 440 440 TYR TYR C . n C 2 409 ALA 409 441 441 ALA ALA C . n C 2 410 ASP 410 442 442 ASP ASP C . n C 2 411 CYS 411 443 443 CYS CYS C . n C 2 412 LEU 412 444 444 LEU LEU C . n C 2 413 LYS 413 445 445 LYS LYS C . n C 2 414 GLN 414 446 446 GLN GLN C . n C 2 415 LEU 415 447 447 LEU LEU C . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code D 3 NAG 1 601 601 NAG NAG A . E 3 NAG 1 602 602 NAG NAG A . F 3 NAG 1 603 603 NAG NAG A . G 3 NAG 1 604 604 NAG NAG A . H 4 ZN 1 605 1 ZN ZN A . I 4 ZN 1 606 2 ZN ZN A . J 5 C5P 1 607 1 C5P C5P A . K 3 NAG 1 601 601 NAG NAG B . L 3 NAG 1 602 602 NAG NAG B . M 3 NAG 2 603 603 NAG NAG B . N 3 NAG 1 604 604 NAG NAG B . O 3 NAG 1 605 605 NAG NAG B . P 4 ZN 1 606 5 ZN ZN B . Q 4 ZN 1 607 6 ZN ZN B . R 6 GOL 1 608 1 GOL GOL B . S 6 GOL 1 609 2 GOL GOL B . T 7 MLI 1 610 1 MLI MLI B . U 8 RP5 1 611 1 RP5 RP5 B . V 3 NAG 1 601 601 NAG NAG C . W 3 NAG 1 602 602 NAG NAG C . X 3 NAG 1 603 603 NAG NAG C . Y 3 NAG 1 604 604 NAG NAG C . Z 4 ZN 1 605 3 ZN ZN C . AA 4 ZN 1 606 4 ZN ZN C . BA 5 C5P 1 607 3 C5P C5P C . CA 9 SCN 1 608 1 SCN SCN C . DA 9 SCN 1 609 2 SCN SCN C . EA 10 HOH 1 701 58 HOH HOH A . EA 10 HOH 2 702 21 HOH HOH A . EA 10 HOH 3 703 61 HOH HOH A . EA 10 HOH 4 704 95 HOH HOH A . EA 10 HOH 5 705 24 HOH HOH A . EA 10 HOH 6 706 94 HOH HOH A . EA 10 HOH 7 707 25 HOH HOH A . EA 10 HOH 8 708 20 HOH HOH A . EA 10 HOH 9 709 2 HOH HOH A . EA 10 HOH 10 710 23 HOH HOH A . EA 10 HOH 11 711 3 HOH HOH A . EA 10 HOH 12 712 1 HOH HOH A . EA 10 HOH 13 713 87 HOH HOH A . EA 10 HOH 14 714 125 HOH HOH A . EA 10 HOH 15 715 18 HOH HOH A . EA 10 HOH 16 716 19 HOH HOH A . EA 10 HOH 17 717 22 HOH HOH A . EA 10 HOH 18 718 108 HOH HOH A . EA 10 HOH 19 719 60 HOH HOH A . FA 10 HOH 1 701 91 HOH HOH B . FA 10 HOH 2 702 122 HOH HOH B . FA 10 HOH 3 703 65 HOH HOH B . FA 10 HOH 4 704 68 HOH HOH B . FA 10 HOH 5 705 63 HOH HOH B . FA 10 HOH 6 706 62 HOH HOH B . FA 10 HOH 7 707 90 HOH HOH B . FA 10 HOH 8 708 117 HOH HOH B . FA 10 HOH 9 709 97 HOH HOH B . FA 10 HOH 10 710 93 HOH HOH B . FA 10 HOH 11 711 70 HOH HOH B . FA 10 HOH 12 712 92 HOH HOH B . FA 10 HOH 13 713 69 HOH HOH B . FA 10 HOH 14 714 74 HOH HOH B . FA 10 HOH 15 715 101 HOH HOH B . FA 10 HOH 16 716 100 HOH HOH B . FA 10 HOH 17 717 64 HOH HOH B . FA 10 HOH 18 718 96 HOH HOH B . FA 10 HOH 19 719 8 HOH HOH B . FA 10 HOH 20 720 72 HOH HOH B . FA 10 HOH 21 721 99 HOH HOH B . FA 10 HOH 22 722 78 HOH HOH B . FA 10 HOH 23 723 75 HOH HOH B . FA 10 HOH 24 724 5 HOH HOH B . FA 10 HOH 25 725 10 HOH HOH B . FA 10 HOH 26 726 104 HOH HOH B . FA 10 HOH 27 727 67 HOH HOH B . FA 10 HOH 28 728 66 HOH HOH B . FA 10 HOH 29 729 89 HOH HOH B . FA 10 HOH 30 730 102 HOH HOH B . FA 10 HOH 31 731 103 HOH HOH B . FA 10 HOH 32 732 110 HOH HOH B . FA 10 HOH 33 733 86 HOH HOH B . FA 10 HOH 34 734 9 HOH HOH B . FA 10 HOH 35 735 115 HOH HOH B . FA 10 HOH 36 736 109 HOH HOH B . FA 10 HOH 37 737 52 HOH HOH B . FA 10 HOH 38 738 7 HOH HOH B . FA 10 HOH 39 739 11 HOH HOH B . FA 10 HOH 40 740 124 HOH HOH B . FA 10 HOH 41 741 45 HOH HOH B . FA 10 HOH 42 742 119 HOH HOH B . FA 10 HOH 43 743 16 HOH HOH B . FA 10 HOH 44 744 98 HOH HOH B . FA 10 HOH 45 745 73 HOH HOH B . FA 10 HOH 46 746 76 HOH HOH B . FA 10 HOH 47 747 112 HOH HOH B . FA 10 HOH 48 748 118 HOH HOH B . FA 10 HOH 49 749 123 HOH HOH B . FA 10 HOH 50 750 88 HOH HOH B . FA 10 HOH 51 751 114 HOH HOH B . FA 10 HOH 52 752 36 HOH HOH B . FA 10 HOH 53 753 121 HOH HOH B . FA 10 HOH 54 754 71 HOH HOH B . FA 10 HOH 55 755 126 HOH HOH B . FA 10 HOH 56 756 116 HOH HOH B . FA 10 HOH 57 757 83 HOH HOH B . FA 10 HOH 58 758 111 HOH HOH B . FA 10 HOH 59 759 113 HOH HOH B . FA 10 HOH 60 760 120 HOH HOH B . GA 10 HOH 1 701 105 HOH HOH C . GA 10 HOH 2 702 129 HOH HOH C . GA 10 HOH 3 703 12 HOH HOH C . GA 10 HOH 4 704 132 HOH HOH C . GA 10 HOH 5 705 106 HOH HOH C . GA 10 HOH 6 706 41 HOH HOH C . GA 10 HOH 7 707 38 HOH HOH C . GA 10 HOH 8 708 80 HOH HOH C . GA 10 HOH 9 709 85 HOH HOH C . GA 10 HOH 10 710 28 HOH HOH C . GA 10 HOH 11 711 33 HOH HOH C . GA 10 HOH 12 712 34 HOH HOH C . GA 10 HOH 13 713 39 HOH HOH C . GA 10 HOH 14 714 50 HOH HOH C . GA 10 HOH 15 715 15 HOH HOH C . GA 10 HOH 16 716 35 HOH HOH C . GA 10 HOH 17 717 82 HOH HOH C . GA 10 HOH 18 718 48 HOH HOH C . GA 10 HOH 19 719 54 HOH HOH C . GA 10 HOH 20 720 40 HOH HOH C . GA 10 HOH 21 721 84 HOH HOH C . GA 10 HOH 22 722 4 HOH HOH C . GA 10 HOH 23 723 26 HOH HOH C . GA 10 HOH 24 724 42 HOH HOH C . GA 10 HOH 25 725 17 HOH HOH C . GA 10 HOH 26 726 55 HOH HOH C . GA 10 HOH 27 727 127 HOH HOH C . GA 10 HOH 28 728 14 HOH HOH C . GA 10 HOH 29 729 43 HOH HOH C . GA 10 HOH 30 730 27 HOH HOH C . GA 10 HOH 31 731 29 HOH HOH C . GA 10 HOH 32 732 37 HOH HOH C . GA 10 HOH 33 733 57 HOH HOH C . GA 10 HOH 34 734 81 HOH HOH C . GA 10 HOH 35 735 130 HOH HOH C . GA 10 HOH 36 736 49 HOH HOH C . GA 10 HOH 37 737 30 HOH HOH C . GA 10 HOH 38 738 79 HOH HOH C . GA 10 HOH 39 739 31 HOH HOH C . GA 10 HOH 40 740 13 HOH HOH C . GA 10 HOH 41 741 107 HOH HOH C . GA 10 HOH 42 742 32 HOH HOH C . GA 10 HOH 43 743 131 HOH HOH C . GA 10 HOH 44 744 46 HOH HOH C . GA 10 HOH 45 745 44 HOH HOH C . GA 10 HOH 46 746 56 HOH HOH C . GA 10 HOH 47 747 51 HOH HOH C . GA 10 HOH 48 748 128 HOH HOH C . GA 10 HOH 49 749 6 HOH HOH C . GA 10 HOH 50 750 47 HOH HOH C . GA 10 HOH 51 751 53 HOH HOH C . # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_defined_assembly ? monomeric 1 2 author_defined_assembly ? monomeric 1 3 author_defined_assembly ? monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,D,E,F,G,H,I,J,EA 2 1 B,K,L,M,N,O,P,Q,R,S,T,U,FA 3 1 C,V,W,X,Y,Z,AA,BA,CA,DA,GA # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 OD2 ? A ASP 13 ? A ASP 45 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 NE2 ? A HIS 15 ? A HIS 47 ? 1_555 111.8 ? 2 OD2 ? A ASP 13 ? A ASP 45 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 OD2 ? A ASP 78 ? A ASP 110 ? 1_555 75.6 ? 3 NE2 ? A HIS 15 ? A HIS 47 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 OD2 ? A ASP 78 ? A ASP 110 ? 1_555 87.3 ? 4 OD2 ? A ASP 13 ? A ASP 45 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 NE2 ? A HIS 263 ? A HIS 295 ? 1_555 101.4 ? 5 NE2 ? A HIS 15 ? A HIS 47 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 NE2 ? A HIS 263 ? A HIS 295 ? 1_555 97.6 ? 6 OD2 ? A ASP 78 ? A ASP 110 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 NE2 ? A HIS 263 ? A HIS 295 ? 1_555 175.0 ? 7 OD2 ? A ASP 13 ? A ASP 45 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 O2P ? J C5P . ? A C5P 607 ? 1_555 128.1 ? 8 NE2 ? A HIS 15 ? A HIS 47 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 O2P ? J C5P . ? A C5P 607 ? 1_555 114.1 ? 9 OD2 ? A ASP 78 ? A ASP 110 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 O2P ? J C5P . ? A C5P 607 ? 1_555 83.7 ? 10 NE2 ? A HIS 263 ? A HIS 295 ? 1_555 ZN ? I ZN . ? A ZN 606 ? 1_555 O2P ? J C5P . ? A C5P 607 ? 1_555 95.3 ? 11 OD2 ? A ASP 78 ? A ASP 110 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 OD1 ? A ASN 119 ? A ASN 151 ? 1_555 105.3 ? 12 OD2 ? A ASP 78 ? A ASP 110 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 NE2 ? A HIS 220 ? A HIS 252 ? 1_555 87.7 ? 13 OD1 ? A ASN 119 ? A ASN 151 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 NE2 ? A HIS 220 ? A HIS 252 ? 1_555 78.4 ? 14 OD2 ? A ASP 78 ? A ASP 110 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 ND1 ? A HIS 261 ? A HIS 293 ? 1_555 160.0 ? 15 OD1 ? A ASN 119 ? A ASN 151 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 ND1 ? A HIS 261 ? A HIS 293 ? 1_555 94.6 ? 16 NE2 ? A HIS 220 ? A HIS 252 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 ND1 ? A HIS 261 ? A HIS 293 ? 1_555 93.9 ? 17 OD2 ? A ASP 78 ? A ASP 110 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 O1P ? J C5P . ? A C5P 607 ? 1_555 80.8 ? 18 OD1 ? A ASN 119 ? A ASN 151 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 O1P ? J C5P . ? A C5P 607 ? 1_555 85.7 ? 19 NE2 ? A HIS 220 ? A HIS 252 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 O1P ? J C5P . ? A C5P 607 ? 1_555 157.1 ? 20 ND1 ? A HIS 261 ? A HIS 293 ? 1_555 ZN ? H ZN . ? A ZN 605 ? 1_555 O1P ? J C5P . ? A C5P 607 ? 1_555 103.7 ? 21 OD2 ? B ASP 13 ? B ASP 45 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 NE2 ? B HIS 15 ? B HIS 47 ? 1_555 108.7 ? 22 OD2 ? B ASP 13 ? B ASP 45 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 OD2 ? B ASP 78 ? B ASP 110 ? 1_555 86.5 ? 23 NE2 ? B HIS 15 ? B HIS 47 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 OD2 ? B ASP 78 ? B ASP 110 ? 1_555 76.7 ? 24 OD2 ? B ASP 13 ? B ASP 45 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 NE2 ? B HIS 263 ? B HIS 295 ? 1_555 97.8 ? 25 NE2 ? B HIS 15 ? B HIS 47 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 NE2 ? B HIS 263 ? B HIS 295 ? 1_555 95.8 ? 26 OD2 ? B ASP 78 ? B ASP 110 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 NE2 ? B HIS 263 ? B HIS 295 ? 1_555 172.3 ? 27 OD2 ? B ASP 13 ? B ASP 45 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 O3X ? U RP5 . ? B RP5 611 ? 1_555 152.5 ? 28 NE2 ? B HIS 15 ? B HIS 47 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 O3X ? U RP5 . ? B RP5 611 ? 1_555 97.9 ? 29 OD2 ? B ASP 78 ? B ASP 110 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 O3X ? U RP5 . ? B RP5 611 ? 1_555 92.9 ? 30 NE2 ? B HIS 263 ? B HIS 295 ? 1_555 ZN ? P ZN . ? B ZN 606 ? 1_555 O3X ? U RP5 . ? B RP5 611 ? 1_555 86.2 ? 31 OD2 ? B ASP 78 ? B ASP 110 ? 1_555 ZN ? Q ZN . ? B ZN 607 ? 1_555 OD1 ? B ASN 119 ? B ASN 151 ? 1_555 105.3 ? 32 OD2 ? B ASP 78 ? B ASP 110 ? 1_555 ZN ? Q ZN . ? B ZN 607 ? 1_555 NE2 ? B HIS 220 ? B HIS 252 ? 1_555 85.4 ? 33 OD1 ? B ASN 119 ? B ASN 151 ? 1_555 ZN ? Q ZN . ? B ZN 607 ? 1_555 NE2 ? B HIS 220 ? B HIS 252 ? 1_555 83.3 ? 34 OD2 ? B ASP 78 ? B ASP 110 ? 1_555 ZN ? Q ZN . ? B ZN 607 ? 1_555 ND1 ? B HIS 261 ? B HIS 293 ? 1_555 153.1 ? 35 OD1 ? B ASN 119 ? B ASN 151 ? 1_555 ZN ? Q ZN . ? B ZN 607 ? 1_555 ND1 ? B HIS 261 ? B HIS 293 ? 1_555 101.0 ? 36 NE2 ? B HIS 220 ? B HIS 252 ? 1_555 ZN ? Q ZN . ? B ZN 607 ? 1_555 ND1 ? B HIS 261 ? B HIS 293 ? 1_555 103.2 ? 37 OD2 ? C ASP 13 ? C ASP 45 ? 1_555 ZN ? AA ZN . ? C ZN 606 ? 1_555 NE2 ? C HIS 15 ? C HIS 47 ? 1_555 119.3 ? 38 OD2 ? C ASP 13 ? C ASP 45 ? 1_555 ZN ? AA ZN . ? C ZN 606 ? 1_555 OD2 ? C ASP 78 ? C ASP 110 ? 1_555 79.3 ? 39 NE2 ? C HIS 15 ? C HIS 47 ? 1_555 ZN ? AA ZN . ? C ZN 606 ? 1_555 OD2 ? C ASP 78 ? C ASP 110 ? 1_555 98.3 ? 40 OD2 ? C ASP 13 ? C ASP 45 ? 1_555 ZN ? AA ZN . ? C ZN 606 ? 1_555 NE2 ? C HIS 263 ? C HIS 295 ? 1_555 99.5 ? 41 NE2 ? C HIS 15 ? C HIS 47 ? 1_555 ZN ? AA ZN . ? C ZN 606 ? 1_555 NE2 ? C HIS 263 ? C HIS 295 ? 1_555 87.0 ? 42 OD2 ? C ASP 78 ? C ASP 110 ? 1_555 ZN ? AA ZN . ? C ZN 606 ? 1_555 NE2 ? C HIS 263 ? C HIS 295 ? 1_555 174.4 ? 43 OD2 ? C ASP 78 ? C ASP 110 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 OD1 ? C ASN 119 ? C ASN 151 ? 1_555 99.1 ? 44 OD2 ? C ASP 78 ? C ASP 110 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 NE2 ? C HIS 220 ? C HIS 252 ? 1_555 75.7 ? 45 OD1 ? C ASN 119 ? C ASN 151 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 NE2 ? C HIS 220 ? C HIS 252 ? 1_555 79.8 ? 46 OD2 ? C ASP 78 ? C ASP 110 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 ND1 ? C HIS 261 ? C HIS 293 ? 1_555 139.9 ? 47 OD1 ? C ASN 119 ? C ASN 151 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 ND1 ? C HIS 261 ? C HIS 293 ? 1_555 119.1 ? 48 NE2 ? C HIS 220 ? C HIS 252 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 ND1 ? C HIS 261 ? C HIS 293 ? 1_555 98.2 ? 49 OD2 ? C ASP 78 ? C ASP 110 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 O2P ? BA C5P . ? C C5P 607 ? 1_555 87.1 ? 50 OD1 ? C ASN 119 ? C ASN 151 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 O2P ? BA C5P . ? C C5P 607 ? 1_555 152.1 ? 51 NE2 ? C HIS 220 ? C HIS 252 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 O2P ? BA C5P . ? C C5P 607 ? 1_555 128.0 ? 52 ND1 ? C HIS 261 ? C HIS 293 ? 1_555 ZN ? Z ZN . ? C ZN 605 ? 1_555 O2P ? BA C5P . ? C C5P 607 ? 1_555 65.3 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2016-01-20 2 'Structure model' 1 1 2016-02-03 3 'Structure model' 1 2 2016-03-30 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Database references' 2 3 'Structure model' 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0073 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS ? ? ? 10.5.8 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? 0.3.11 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? 2.5.6 4 ? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot ? ? ? 0.8 5 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 SG B CYS 430 ? ? SG B CYS 443 ? ? 0.50 2 1 ND2 A ASN 356 ? ? C1 A NAG 604 ? ? 1.61 3 1 ZN B ZN 607 ? ? O2X B RP5 611 ? ? 1.69 4 1 ZN C ZN 606 ? ? O3P C C5P 607 ? ? 1.70 5 1 N C LEU 80 ? ? O C HOH 701 ? ? 1.78 6 1 ND2 C ASN 356 ? ? O5 C NAG 604 ? ? 1.88 7 1 OG1 C THR 294 ? B O C HOH 702 ? ? 1.89 8 1 ND2 B ASN 263 ? ? O5 B NAG 604 ? ? 1.90 9 1 CG2 C THR 294 ? A O C HOH 702 ? ? 1.97 10 1 O C GLY 191 ? ? O C HOH 703 ? ? 2.12 11 1 O4 B NAG 602 ? ? O5 B NAG 603 ? ? 2.14 12 1 OD2 B ASP 49 ? ? OG B SER 64 ? ? 2.15 13 1 SG B CYS 430 ? ? CB B CYS 443 ? ? 2.17 14 1 ND2 B ASN 131 ? ? O5 B NAG 602 ? ? 2.19 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CB A HIS 53 ? ? CA A HIS 53 ? ? C A HIS 53 ? ? 122.46 110.40 12.06 2.00 N 2 1 CB A GLN 446 ? ? CA A GLN 446 ? ? C A GLN 446 ? ? 122.89 110.40 12.49 2.00 N 3 1 C B PRO 34 ? ? N B PRO 35 ? ? CD B PRO 35 ? ? 112.60 128.40 -15.80 2.10 Y 4 1 CA B CYS 443 ? ? CB B CYS 443 ? ? SG B CYS 443 ? ? 124.22 114.20 10.02 1.10 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 45 ? ? 39.86 67.81 2 1 HIS A 53 ? ? 178.04 151.46 3 1 ASN A 72 ? ? -162.48 75.05 4 1 ASP A 110 ? ? 52.08 74.91 5 1 ASP A 153 ? ? -87.38 49.66 6 1 GLN A 157 ? ? -47.12 150.21 7 1 ASP A 158 ? ? 73.21 -8.71 8 1 GLN A 159 ? ? -98.84 47.96 9 1 ASN A 200 ? ? -160.99 92.84 10 1 PRO A 216 ? ? -54.16 0.17 11 1 ASN A 222 ? ? 58.99 14.78 12 1 ALA A 227 ? ? 48.23 25.21 13 1 HIS A 252 ? ? -92.75 -63.93 14 1 HIS A 293 ? ? 74.20 -53.08 15 1 VAL A 310 ? ? -143.79 -7.31 16 1 ASP A 382 ? ? -159.66 -158.06 17 1 SER A 417 ? ? -93.86 32.83 18 1 LEU A 447 ? ? -163.59 79.76 19 1 ASP B 45 ? ? 51.88 74.54 20 1 HIS B 53 ? ? -171.77 147.35 21 1 ASN B 72 ? ? -164.40 73.20 22 1 LEU B 80 ? ? 65.58 -6.50 23 1 THR B 108 ? ? -100.64 57.92 24 1 ASP B 110 ? ? 51.60 77.07 25 1 TYR B 154 ? ? 177.95 154.07 26 1 GLN B 157 ? ? -46.23 152.73 27 1 ASP B 158 ? ? 73.19 -14.33 28 1 GLN B 159 ? ? -90.77 30.29 29 1 ASN B 200 ? ? -161.84 67.90 30 1 ASN B 222 ? ? 55.37 13.82 31 1 ALA B 227 ? ? 37.90 34.07 32 1 ASN B 228 ? ? 32.95 63.35 33 1 HIS B 252 ? ? -92.74 -76.80 34 1 TYR B 282 ? ? -99.54 30.18 35 1 HIS B 293 ? ? 74.26 -50.80 36 1 ASN B 356 ? ? -68.59 89.29 37 1 ASP B 382 ? ? -152.12 -156.94 38 1 SER B 417 ? ? -119.85 58.11 39 1 CYS B 443 ? ? -77.24 39.68 40 1 LYS B 445 ? ? -51.74 -5.09 41 1 ASN C 72 ? ? -156.44 76.29 42 1 LEU C 80 ? ? 79.52 -15.87 43 1 ASP C 110 ? ? 44.00 74.36 44 1 ASP C 153 ? ? -79.52 32.94 45 1 GLN C 159 ? ? -100.39 52.16 46 1 ASN C 200 ? ? -160.53 62.06 47 1 PRO C 201 ? ? -69.18 7.76 48 1 PRO C 216 ? ? -62.78 2.55 49 1 ASN C 222 ? ? 58.49 18.58 50 1 LYS C 244 ? ? 38.97 58.36 51 1 HIS C 293 ? ? 63.39 -58.79 52 1 HIS C 293 ? ? 63.39 -58.58 53 1 ARG C 343 ? ? -90.88 -61.68 54 1 ASP C 379 ? ? 49.88 71.04 55 1 ASP C 382 ? ? -153.00 -157.84 56 1 ASP C 399 ? ? 32.01 53.46 57 1 SER C 413 ? ? 58.99 17.35 58 1 TYR C 414 ? ? -49.90 -73.08 59 1 SER C 417 ? ? -88.05 36.01 60 1 GLN C 446 ? ? -139.85 -60.38 # loop_ _pdbx_distant_solvent_atoms.id _pdbx_distant_solvent_atoms.PDB_model_num _pdbx_distant_solvent_atoms.auth_atom_id _pdbx_distant_solvent_atoms.label_alt_id _pdbx_distant_solvent_atoms.auth_asym_id _pdbx_distant_solvent_atoms.auth_comp_id _pdbx_distant_solvent_atoms.auth_seq_id _pdbx_distant_solvent_atoms.PDB_ins_code _pdbx_distant_solvent_atoms.neighbor_macromolecule_distance _pdbx_distant_solvent_atoms.neighbor_ligand_distance 1 1 O ? B HOH 759 ? 6.02 . 2 1 O ? B HOH 760 ? 6.65 . 3 1 O ? C HOH 751 ? . 6.31 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 N 1 A NAG 604 ? O1 ? G NAG 1 O1 2 1 N 1 A NAG 604 ? O3 ? G NAG 1 O3 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 3 N-ACETYL-D-GLUCOSAMINE NAG 4 'ZINC ION' ZN 5 "CYTIDINE-5'-MONOPHOSPHATE" C5P 6 GLYCEROL GOL 7 'MALONATE ION' MLI 8 5-O-phosphono-beta-D-ribofuranose RP5 9 'THIOCYANATE ION' SCN 10 water HOH #