data_5DJC # _entry.id 5DJC # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5DJC WWPDB D_1000213292 # loop_ _pdbx_database_related.db_name _pdbx_database_related.details _pdbx_database_related.db_id _pdbx_database_related.content_type PDB . 5DI8 unspecified PDB . 5DJ0 unspecified PDB . 5DJ2 unspecified PDB . 5DJ6 unspecified PDB . 5DJ8 unspecified PDB . 5DJA unspecified PDB . 5DJD unspecified PDB . 5DJX unspecified PDB . 5DJY unspecified PDB . 5DJZ unspecified PDB . 5DK0 unspecified PDB . 5DK2 unspecified PDB . 5DVK unspecified PDB . 5DVL unspecified PDB . 5DVM unspecified PDB . 5DVN unspecified PDB . 5DVO unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5DJC _pdbx_database_status.recvd_initial_deposition_date 2015-09-01 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Atwell, S.' 1 'Leaver-Fay, A.' 2 'Froning, K.J.' 3 'Aldaz, H.' 4 'Pustilnik, A.' 5 'Lu, F.' 6 'Huang, F.' 7 'Yuan, R.' 8 'Dhanani, S.H.' 9 'Chamberlain, A.K.' 10 'Fitchett, J.R.' 11 'Gutierrez, B.' 12 'Hendle, J.' 13 'Secrist, E.' 14 'Demarest, S.J.' 15 'Kuhlman, B.' 16 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country UK _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev Structure _citation.journal_id_ASTM STRUE6 _citation.journal_id_CSD 2005 _citation.journal_id_ISSN 0969-2126 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 24 _citation.language ? _citation.page_first 641 _citation.page_last 651 _citation.title 'Computationally Designed Bispecific Antibodies using Negative State Repertoires.' _citation.year 2016 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1016/j.str.2016.02.013 _citation.pdbx_database_id_PubMed 26996964 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Leaver-Fay, A.' 1 primary 'Froning, K.J.' 2 primary 'Atwell, S.' 3 primary 'Aldaz, H.' 4 primary 'Pustilnik, A.' 5 primary 'Lu, F.' 6 primary 'Huang, F.' 7 primary 'Yuan, R.' 8 primary 'Hassanali, S.' 9 primary 'Chamberlain, A.K.' 10 primary 'Fitchett, J.R.' 11 primary 'Demarest, S.J.' 12 primary 'Kuhlman, B.' 13 # _cell.entry_id 5DJC _cell.length_a 60.242 _cell.length_b 66.858 _cell.length_c 72.771 _cell.angle_alpha 85.17 _cell.angle_beta 80.71 _cell.angle_gamma 89.69 _cell.Z_PDB 2 _cell.pdbx_unique_axis ? # _symmetry.entry_id 5DJC _symmetry.space_group_name_H-M 'P 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 1 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Ig gamma-1 chain C region' 25506.895 2 ? 'L368V, Y407A' 'UNP residues 104-330' ? 2 polymer man 'Ig gamma-1 chain C region' 26998.326 2 ? 'T366V, K409F' 'UNP residues 104-330' ? 3 polymer syn 'Fc-III peptide' 1533.749 2 ? ? ? ? 4 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 12 ? ? ? ? 5 non-polymer man BETA-D-MANNOSE 180.156 4 ? ? ? ? 6 non-polymer man ALPHA-D-MANNOSE 180.156 8 ? ? ? ? 7 non-polymer man BETA-D-GALACTOSE 180.156 4 ? ? ? ? 8 non-polymer man ALPHA-L-FUCOSE 164.156 4 ? ? ? ? 9 non-polymer syn 'IODIDE ION' 126.904 1 ? ? ? ? 10 water nat water 18.015 189 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;DKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTY RVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCVVKGFYPSDIAVE WESNGQPENNYKTTPPVLDSDGSFFLASKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK ; ;DKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTY RVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCVVKGFYPSDIAVE WESNGQPENNYKTTPPVLDSDGSFFLASKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK ; A,D ? 2 'polypeptide(L)' no no ;HHHHHHHHSGSGSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLEASRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNA KTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLVC LVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSFLTVDKSRWQQGNVFSCSVMHEALHNAYTQKSLSLSPGK ; ;HHHHHHHHSGSGSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLEASRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNA KTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLVC LVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSFLTVDKSRWQQGNVFSCSVMHEALHNAYTQKSLSLSPGK ; B,E ? 3 'polypeptide(L)' no no DCAWHLGELVWCT DCAWHLGELVWCT C,F ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ASP n 1 2 LYS n 1 3 THR n 1 4 HIS n 1 5 THR n 1 6 CYS n 1 7 PRO n 1 8 PRO n 1 9 CYS n 1 10 PRO n 1 11 ALA n 1 12 PRO n 1 13 GLU n 1 14 LEU n 1 15 LEU n 1 16 GLY n 1 17 GLY n 1 18 PRO n 1 19 SER n 1 20 VAL n 1 21 PHE n 1 22 LEU n 1 23 PHE n 1 24 PRO n 1 25 PRO n 1 26 LYS n 1 27 PRO n 1 28 LYS n 1 29 ASP n 1 30 THR n 1 31 LEU n 1 32 MET n 1 33 ILE n 1 34 SER n 1 35 ARG n 1 36 THR n 1 37 PRO n 1 38 GLU n 1 39 VAL n 1 40 THR n 1 41 CYS n 1 42 VAL n 1 43 VAL n 1 44 VAL n 1 45 ASP n 1 46 VAL n 1 47 SER n 1 48 HIS n 1 49 GLU n 1 50 ASP n 1 51 PRO n 1 52 GLU n 1 53 VAL n 1 54 LYS n 1 55 PHE n 1 56 ASN n 1 57 TRP n 1 58 TYR n 1 59 VAL n 1 60 ASP n 1 61 GLY n 1 62 VAL n 1 63 GLU n 1 64 VAL n 1 65 HIS n 1 66 ASN n 1 67 ALA n 1 68 LYS n 1 69 THR n 1 70 LYS n 1 71 PRO n 1 72 ARG n 1 73 GLU n 1 74 GLU n 1 75 GLN n 1 76 TYR n 1 77 ASN n 1 78 SER n 1 79 THR n 1 80 TYR n 1 81 ARG n 1 82 VAL n 1 83 VAL n 1 84 SER n 1 85 VAL n 1 86 LEU n 1 87 THR n 1 88 VAL n 1 89 LEU n 1 90 HIS n 1 91 GLN n 1 92 ASP n 1 93 TRP n 1 94 LEU n 1 95 ASN n 1 96 GLY n 1 97 LYS n 1 98 GLU n 1 99 TYR n 1 100 LYS n 1 101 CYS n 1 102 LYS n 1 103 VAL n 1 104 SER n 1 105 ASN n 1 106 LYS n 1 107 ALA n 1 108 LEU n 1 109 PRO n 1 110 ALA n 1 111 PRO n 1 112 ILE n 1 113 GLU n 1 114 LYS n 1 115 THR n 1 116 ILE n 1 117 SER n 1 118 LYS n 1 119 ALA n 1 120 LYS n 1 121 GLY n 1 122 GLN n 1 123 PRO n 1 124 ARG n 1 125 GLU n 1 126 PRO n 1 127 GLN n 1 128 VAL n 1 129 TYR n 1 130 THR n 1 131 LEU n 1 132 PRO n 1 133 PRO n 1 134 SER n 1 135 ARG n 1 136 GLU n 1 137 GLU n 1 138 MET n 1 139 THR n 1 140 LYS n 1 141 ASN n 1 142 GLN n 1 143 VAL n 1 144 SER n 1 145 LEU n 1 146 THR n 1 147 CYS n 1 148 VAL n 1 149 VAL n 1 150 LYS n 1 151 GLY n 1 152 PHE n 1 153 TYR n 1 154 PRO n 1 155 SER n 1 156 ASP n 1 157 ILE n 1 158 ALA n 1 159 VAL n 1 160 GLU n 1 161 TRP n 1 162 GLU n 1 163 SER n 1 164 ASN n 1 165 GLY n 1 166 GLN n 1 167 PRO n 1 168 GLU n 1 169 ASN n 1 170 ASN n 1 171 TYR n 1 172 LYS n 1 173 THR n 1 174 THR n 1 175 PRO n 1 176 PRO n 1 177 VAL n 1 178 LEU n 1 179 ASP n 1 180 SER n 1 181 ASP n 1 182 GLY n 1 183 SER n 1 184 PHE n 1 185 PHE n 1 186 LEU n 1 187 ALA n 1 188 SER n 1 189 LYS n 1 190 LEU n 1 191 THR n 1 192 VAL n 1 193 ASP n 1 194 LYS n 1 195 SER n 1 196 ARG n 1 197 TRP n 1 198 GLN n 1 199 GLN n 1 200 GLY n 1 201 ASN n 1 202 VAL n 1 203 PHE n 1 204 SER n 1 205 CYS n 1 206 SER n 1 207 VAL n 1 208 MET n 1 209 HIS n 1 210 GLU n 1 211 ALA n 1 212 LEU n 1 213 HIS n 1 214 ASN n 1 215 HIS n 1 216 TYR n 1 217 THR n 1 218 GLN n 1 219 LYS n 1 220 SER n 1 221 LEU n 1 222 SER n 1 223 LEU n 1 224 SER n 1 225 PRO n 1 226 GLY n 1 227 LYS n 2 1 HIS n 2 2 HIS n 2 3 HIS n 2 4 HIS n 2 5 HIS n 2 6 HIS n 2 7 HIS n 2 8 HIS n 2 9 SER n 2 10 GLY n 2 11 SER n 2 12 GLY n 2 13 SER n 2 14 ASP n 2 15 LYS n 2 16 THR n 2 17 HIS n 2 18 THR n 2 19 CYS n 2 20 PRO n 2 21 PRO n 2 22 CYS n 2 23 PRO n 2 24 ALA n 2 25 PRO n 2 26 GLU n 2 27 LEU n 2 28 LEU n 2 29 GLY n 2 30 GLY n 2 31 PRO n 2 32 SER n 2 33 VAL n 2 34 PHE n 2 35 LEU n 2 36 PHE n 2 37 PRO n 2 38 PRO n 2 39 LYS n 2 40 PRO n 2 41 LYS n 2 42 ASP n 2 43 THR n 2 44 LEU n 2 45 GLU n 2 46 ALA n 2 47 SER n 2 48 ARG n 2 49 THR n 2 50 PRO n 2 51 GLU n 2 52 VAL n 2 53 THR n 2 54 CYS n 2 55 VAL n 2 56 VAL n 2 57 VAL n 2 58 ASP n 2 59 VAL n 2 60 SER n 2 61 HIS n 2 62 GLU n 2 63 ASP n 2 64 PRO n 2 65 GLU n 2 66 VAL n 2 67 LYS n 2 68 PHE n 2 69 ASN n 2 70 TRP n 2 71 TYR n 2 72 VAL n 2 73 ASP n 2 74 GLY n 2 75 VAL n 2 76 GLU n 2 77 VAL n 2 78 HIS n 2 79 ASN n 2 80 ALA n 2 81 LYS n 2 82 THR n 2 83 LYS n 2 84 PRO n 2 85 ARG n 2 86 GLU n 2 87 GLU n 2 88 GLN n 2 89 TYR n 2 90 ASN n 2 91 SER n 2 92 THR n 2 93 TYR n 2 94 ARG n 2 95 VAL n 2 96 VAL n 2 97 SER n 2 98 VAL n 2 99 LEU n 2 100 THR n 2 101 VAL n 2 102 LEU n 2 103 HIS n 2 104 GLN n 2 105 ASP n 2 106 TRP n 2 107 LEU n 2 108 ASN n 2 109 GLY n 2 110 LYS n 2 111 GLU n 2 112 TYR n 2 113 LYS n 2 114 CYS n 2 115 LYS n 2 116 VAL n 2 117 SER n 2 118 ASN n 2 119 LYS n 2 120 ALA n 2 121 LEU n 2 122 PRO n 2 123 ALA n 2 124 PRO n 2 125 ILE n 2 126 GLU n 2 127 LYS n 2 128 THR n 2 129 ILE n 2 130 SER n 2 131 LYS n 2 132 ALA n 2 133 LYS n 2 134 GLY n 2 135 GLN n 2 136 PRO n 2 137 ARG n 2 138 GLU n 2 139 PRO n 2 140 GLN n 2 141 VAL n 2 142 TYR n 2 143 THR n 2 144 LEU n 2 145 PRO n 2 146 PRO n 2 147 SER n 2 148 ARG n 2 149 GLU n 2 150 GLU n 2 151 MET n 2 152 THR n 2 153 LYS n 2 154 ASN n 2 155 GLN n 2 156 VAL n 2 157 SER n 2 158 LEU n 2 159 VAL n 2 160 CYS n 2 161 LEU n 2 162 VAL n 2 163 LYS n 2 164 GLY n 2 165 PHE n 2 166 TYR n 2 167 PRO n 2 168 SER n 2 169 ASP n 2 170 ILE n 2 171 ALA n 2 172 VAL n 2 173 GLU n 2 174 TRP n 2 175 GLU n 2 176 SER n 2 177 ASN n 2 178 GLY n 2 179 GLN n 2 180 PRO n 2 181 GLU n 2 182 ASN n 2 183 ASN n 2 184 TYR n 2 185 LYS n 2 186 THR n 2 187 THR n 2 188 PRO n 2 189 PRO n 2 190 VAL n 2 191 LEU n 2 192 ASP n 2 193 SER n 2 194 ASP n 2 195 GLY n 2 196 SER n 2 197 PHE n 2 198 PHE n 2 199 LEU n 2 200 TYR n 2 201 SER n 2 202 PHE n 2 203 LEU n 2 204 THR n 2 205 VAL n 2 206 ASP n 2 207 LYS n 2 208 SER n 2 209 ARG n 2 210 TRP n 2 211 GLN n 2 212 GLN n 2 213 GLY n 2 214 ASN n 2 215 VAL n 2 216 PHE n 2 217 SER n 2 218 CYS n 2 219 SER n 2 220 VAL n 2 221 MET n 2 222 HIS n 2 223 GLU n 2 224 ALA n 2 225 LEU n 2 226 HIS n 2 227 ASN n 2 228 ALA n 2 229 TYR n 2 230 THR n 2 231 GLN n 2 232 LYS n 2 233 SER n 2 234 LEU n 2 235 SER n 2 236 LEU n 2 237 SER n 2 238 PRO n 2 239 GLY n 2 240 LYS n 3 1 ASP n 3 2 CYS n 3 3 ALA n 3 4 TRP n 3 5 HIS n 3 6 LEU n 3 7 GLY n 3 8 GLU n 3 9 LEU n 3 10 VAL n 3 11 TRP n 3 12 CYS n 3 13 THR n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample 'Biological sequence' 1 227 Human ? IGHG1 ? ? ? ? 'transient expression' ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? plasmid ? ? ? ? ? ? 2 1 sample 'Biological sequence' 1 240 Human ? IGHG1 ? ? ? ? 'transient expression' ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? plasmid ? ? ? ? ? ? # _pdbx_entity_src_syn.entity_id 3 _pdbx_entity_src_syn.pdbx_src_id 1 _pdbx_entity_src_syn.pdbx_alt_source_flag sample _pdbx_entity_src_syn.pdbx_beg_seq_num 1 _pdbx_entity_src_syn.pdbx_end_seq_num 13 _pdbx_entity_src_syn.organism_scientific 'synthetic construct' _pdbx_entity_src_syn.organism_common_name ? _pdbx_entity_src_syn.ncbi_taxonomy_id 32630 _pdbx_entity_src_syn.details 'CPC Scientific Inc., Sunnyvale CA' # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.pdbx_db_isoform _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin 1 UNP IGHG1_HUMAN P01857 ? 1 ;DKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTY RVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVE WESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK ; 104 2 UNP IGHG1_HUMAN P01857 ? 2 ;DKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTY RVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVE WESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK ; 104 3 PDB 5DJC 5DJC ? 3 ? 1 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5DJC A 1 ? 227 ? P01857 104 ? 330 ? 221 447 2 2 5DJC B 14 ? 240 ? P01857 104 ? 330 ? 221 447 3 3 5DJC C 1 ? 13 ? 5DJC 1 ? 13 ? 1 13 4 1 5DJC D 1 ? 227 ? P01857 104 ? 330 ? 221 447 5 2 5DJC E 14 ? 240 ? P01857 104 ? 330 ? 221 447 6 3 5DJC F 1 ? 13 ? 5DJC 1 ? 13 ? 1 13 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 5DJC GLU A 136 ? UNP P01857 ASP 239 variant 356 1 1 5DJC MET A 138 ? UNP P01857 LEU 241 variant 358 2 1 5DJC VAL A 148 ? UNP P01857 LEU 251 'engineered mutation' 368 3 1 5DJC ALA A 187 ? UNP P01857 TYR 290 'engineered mutation' 407 4 2 5DJC HIS B 1 ? UNP P01857 ? ? 'expression tag' 208 5 2 5DJC HIS B 2 ? UNP P01857 ? ? 'expression tag' 209 6 2 5DJC HIS B 3 ? UNP P01857 ? ? 'expression tag' 210 7 2 5DJC HIS B 4 ? UNP P01857 ? ? 'expression tag' 211 8 2 5DJC HIS B 5 ? UNP P01857 ? ? 'expression tag' 212 9 2 5DJC HIS B 6 ? UNP P01857 ? ? 'expression tag' 213 10 2 5DJC HIS B 7 ? UNP P01857 ? ? 'expression tag' 214 11 2 5DJC HIS B 8 ? UNP P01857 ? ? 'expression tag' 215 12 2 5DJC SER B 9 ? UNP P01857 ? ? 'expression tag' 216 13 2 5DJC GLY B 10 ? UNP P01857 ? ? 'expression tag' 217 14 2 5DJC SER B 11 ? UNP P01857 ? ? 'expression tag' 218 15 2 5DJC GLY B 12 ? UNP P01857 ? ? 'expression tag' 219 16 2 5DJC SER B 13 ? UNP P01857 ? ? 'expression tag' 220 17 2 5DJC GLU B 45 ? UNP P01857 MET 135 'engineered mutation' 252 18 2 5DJC ALA B 46 ? UNP P01857 ILE 136 'engineered mutation' 253 19 2 5DJC GLU B 149 ? UNP P01857 ASP 239 variant 356 20 2 5DJC MET B 151 ? UNP P01857 LEU 241 variant 358 21 2 5DJC VAL B 159 ? UNP P01857 THR 249 'engineered mutation' 366 22 2 5DJC PHE B 202 ? UNP P01857 LYS 292 'engineered mutation' 409 23 2 5DJC ALA B 228 ? UNP P01857 HIS 318 'engineered mutation' 435 24 4 5DJC GLU D 136 ? UNP P01857 ASP 239 variant 356 25 4 5DJC MET D 138 ? UNP P01857 LEU 241 variant 358 26 4 5DJC VAL D 148 ? UNP P01857 LEU 251 'engineered mutation' 368 27 4 5DJC ALA D 187 ? UNP P01857 TYR 290 'engineered mutation' 407 28 5 5DJC HIS E 1 ? UNP P01857 ? ? 'expression tag' 208 29 5 5DJC HIS E 2 ? UNP P01857 ? ? 'expression tag' 209 30 5 5DJC HIS E 3 ? UNP P01857 ? ? 'expression tag' 210 31 5 5DJC HIS E 4 ? UNP P01857 ? ? 'expression tag' 211 32 5 5DJC HIS E 5 ? UNP P01857 ? ? 'expression tag' 212 33 5 5DJC HIS E 6 ? UNP P01857 ? ? 'expression tag' 213 34 5 5DJC HIS E 7 ? UNP P01857 ? ? 'expression tag' 214 35 5 5DJC HIS E 8 ? UNP P01857 ? ? 'expression tag' 215 36 5 5DJC SER E 9 ? UNP P01857 ? ? 'expression tag' 216 37 5 5DJC GLY E 10 ? UNP P01857 ? ? 'expression tag' 217 38 5 5DJC SER E 11 ? UNP P01857 ? ? 'expression tag' 218 39 5 5DJC GLY E 12 ? UNP P01857 ? ? 'expression tag' 219 40 5 5DJC SER E 13 ? UNP P01857 ? ? 'expression tag' 220 41 5 5DJC GLU E 45 ? UNP P01857 MET 135 'engineered mutation' 252 42 5 5DJC ALA E 46 ? UNP P01857 ILE 136 'engineered mutation' 253 43 5 5DJC GLU E 149 ? UNP P01857 ASP 239 variant 356 44 5 5DJC MET E 151 ? UNP P01857 LEU 241 variant 358 45 5 5DJC VAL E 159 ? UNP P01857 THR 249 'engineered mutation' 366 46 5 5DJC PHE E 202 ? UNP P01857 LYS 292 'engineered mutation' 409 47 5 5DJC ALA E 228 ? UNP P01857 HIS 318 'engineered mutation' 435 48 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FUC saccharide . ALPHA-L-FUCOSE ? 'C6 H12 O5' 164.156 GAL D-saccharide . BETA-D-GALACTOSE ? 'C6 H12 O6' 180.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 IOD non-polymer . 'IODIDE ION' ? 'I -1' 126.904 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5DJC _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.67 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 53.88 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 294 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '17% PEG 3350 + 100mM Ammonium Iodide' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.ambient_environment ? _diffrn.ambient_temp 193 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details 'Diamond (111)' _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'RAYONIX MX-225' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2013-10-02 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # loop_ _diffrn_radiation_wavelength.id _diffrn_radiation_wavelength.wavelength _diffrn_radiation_wavelength.wt 1 0.9793 1.0 2 0.97931 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'APS BEAMLINE 31-ID' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.97931 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 31-ID _diffrn_source.pdbx_synchrotron_site APS # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5DJC _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.100 _reflns.d_resolution_low 30.00 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 62804 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 96.400 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 2.000 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value 0.063 _reflns.pdbx_netI_over_av_sigmaI 8.950 _reflns.pdbx_netI_over_sigmaI 6.300 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all 0.092 _reflns.pdbx_Rpim_I_all 0.065 _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all 123662 _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # loop_ _reflns_shell.d_res_high _reflns_shell.d_res_low _reflns_shell.meanI_over_sigI_all _reflns_shell.meanI_over_sigI_obs _reflns_shell.number_measured_all _reflns_shell.number_measured_obs _reflns_shell.number_possible _reflns_shell.number_unique_all _reflns_shell.number_unique_obs _reflns_shell.percent_possible_all _reflns_shell.percent_possible_obs _reflns_shell.Rmerge_F_all _reflns_shell.Rmerge_F_obs _reflns_shell.Rmerge_I_all _reflns_shell.Rmerge_I_obs _reflns_shell.meanI_over_sigI_gt _reflns_shell.meanI_over_uI_all _reflns_shell.meanI_over_uI_gt _reflns_shell.number_measured_gt _reflns_shell.number_unique_gt _reflns_shell.percent_possible_gt _reflns_shell.Rmerge_F_gt _reflns_shell.Rmerge_I_gt _reflns_shell.pdbx_redundancy _reflns_shell.pdbx_Rsym_value _reflns_shell.pdbx_chi_squared _reflns_shell.pdbx_netI_over_sigmaI_all _reflns_shell.pdbx_netI_over_sigmaI_obs _reflns_shell.pdbx_Rrim_I_all _reflns_shell.pdbx_Rpim_I_all _reflns_shell.pdbx_rejects _reflns_shell.pdbx_ordinal _reflns_shell.pdbx_diffrn_id _reflns_shell.pdbx_CC_half _reflns_shell.pdbx_R_split 2.100 2.210 ? 2.900 17079 ? ? 9071 ? 95.200 ? ? ? ? 0.264 ? ? ? ? ? ? ? ? 1.900 0.264 ? ? 1.300 ? 0.630 0 1 1 ? ? 2.210 2.350 ? 3.500 17023 ? ? 8627 ? 96.100 ? ? ? ? 0.218 ? ? ? ? ? ? ? ? 2.000 0.218 ? ? 1.700 ? 0.516 0 2 1 ? ? 2.350 2.510 ? 5.700 16304 ? ? 8213 ? 96.500 ? ? ? ? 0.136 ? ? ? ? ? ? ? ? 2.000 0.136 ? ? 2.400 ? 0.325 0 3 1 ? ? 2.510 2.710 ? 8.100 15185 ? ? 7635 ? 96.900 ? ? ? ? 0.095 ? ? ? ? ? ? ? ? 2.000 0.095 ? ? 3.400 ? 0.211 0 4 1 ? ? 2.710 2.970 ? 11.300 13919 ? ? 6994 ? 97.100 ? ? ? ? 0.067 ? ? ? ? ? ? ? ? 2.000 0.067 ? ? 5.200 ? 0.125 0 5 1 ? ? 2.970 3.320 ? 13.700 12709 ? ? 6396 ? 97.200 ? ? ? ? 0.053 ? ? ? ? ? ? ? ? 2.000 0.053 ? ? 8.800 ? 0.064 0 6 1 ? ? 3.320 3.830 ? 15.600 11159 ? ? 5607 ? 97.400 ? ? ? ? 0.043 ? ? ? ? ? ? ? ? 2.000 0.043 ? ? 12.700 ? 0.040 0 7 1 ? ? 3.830 4.700 ? 18.100 9438 ? ? 4758 ? 97.300 ? ? ? ? 0.038 ? ? ? ? ? ? ? ? 2.000 0.038 ? ? 15.100 ? 0.030 0 8 1 ? ? 4.700 6.640 ? 15.200 7355 ? ? 3696 ? 97.700 ? ? ? ? 0.042 ? ? ? ? ? ? ? ? 2.000 0.042 ? ? 16.000 ? 0.029 0 9 1 ? ? 6.640 71.559 ? 14.500 3491 ? ? 1807 ? 88.100 ? ? ? ? 0.044 ? ? ? ? ? ? ? ? 1.900 0.044 ? ? 16.500 ? 0.023 0 10 1 ? ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 5DJC _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 59555 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 30.00 _refine.ls_d_res_high 2.10 _refine.ls_percent_reflns_obs 96.27 _refine.ls_R_factor_obs 0.23192 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.22909 _refine.ls_R_factor_R_free 0.28465 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.1 _refine.ls_number_reflns_R_free 3179 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.946 _refine.correlation_coeff_Fo_to_Fc_free 0.918 _refine.B_iso_mean 43.670 _refine.aniso_B[1][1] -2.23 _refine.aniso_B[2][2] -1.29 _refine.aniso_B[3][3] 3.40 _refine.aniso_B[1][2] -0.01 _refine.aniso_B[1][3] -0.30 _refine.aniso_B[2][3] 1.28 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ? _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.241 _refine.pdbx_overall_ESU_R_Free 0.215 _refine.overall_SU_ML 0.198 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 7.935 _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6653 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 385 _refine_hist.number_atoms_solvent 189 _refine_hist.number_atoms_total 7227 _refine_hist.d_res_high 2.10 _refine_hist.d_res_low 30.00 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.007 0.020 ? 7264 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.177 2.017 ? 9983 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 5.754 5.000 ? 846 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 35.293 25.000 ? 286 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 14.698 15.000 ? 1078 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 16.960 15.000 ? 19 'X-RAY DIFFRACTION' ? r_chiral_restr 0.071 0.200 ? 1205 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.005 0.022 ? 5291 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_scbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_scbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? r_scangle_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_long_range_B_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_long_range_B_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.100 _refine_ls_shell.d_res_low 2.154 _refine_ls_shell.number_reflns_R_work 4333 _refine_ls_shell.R_factor_R_work 0.376 _refine_ls_shell.percent_reflns_obs 94.38 _refine_ls_shell.R_factor_R_free 0.389 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 222 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_obs ? _refine_ls_shell.number_reflns_obs ? # _struct.entry_id 5DJC _struct.title 'Fc Heterodimer Design 8.1 L368V/Y407A + T366V/K409F' _struct.pdbx_descriptor 'Ig gamma-1 chain C region, Fc-III peptide' _struct.pdbx_model_details 'Design XXX' _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5DJC _struct_keywords.text 'Heterodimer, Immunoglobulin, CH3, Fc, Bispecific Antibody, IMMUNE SYSTEM' _struct_keywords.pdbx_keywords 'IMMUNE SYSTEM' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 1 ? E N N 2 ? F N N 3 ? G N N 4 ? H N N 4 ? I N N 5 ? J N N 6 ? K N N 4 ? L N N 7 ? M N N 8 ? N N N 6 ? O N N 4 ? P N N 4 ? Q N N 5 ? R N N 6 ? S N N 4 ? T N N 7 ? U N N 6 ? V N N 8 ? W N N 4 ? X N N 4 ? Y N N 5 ? Z N N 6 ? AA N N 4 ? BA N N 7 ? CA N N 8 ? DA N N 6 ? EA N N 9 ? FA N N 4 ? GA N N 4 ? HA N N 5 ? IA N N 6 ? JA N N 4 ? KA N N 7 ? LA N N 6 ? MA N N 8 ? NA N N 10 ? OA N N 10 ? PA N N 10 ? QA N N 10 ? RA N N 10 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 LYS A 26 ? MET A 32 ? LYS A 246 MET A 252 1 ? 7 HELX_P HELX_P2 AA2 LEU A 89 ? ASN A 95 ? LEU A 309 ASN A 315 1 ? 7 HELX_P HELX_P3 AA3 SER A 134 ? MET A 138 ? SER A 354 MET A 358 5 ? 5 HELX_P HELX_P4 AA4 LYS A 194 ? GLN A 199 ? LYS A 414 GLN A 419 1 ? 6 HELX_P HELX_P5 AA5 LEU A 212 ? TYR A 216 ? LEU A 432 TYR A 436 5 ? 5 HELX_P HELX_P6 AA6 LYS B 39 ? GLU B 45 ? LYS B 246 GLU B 252 1 ? 7 HELX_P HELX_P7 AA7 LEU B 102 ? ASN B 108 ? LEU B 309 ASN B 315 1 ? 7 HELX_P HELX_P8 AA8 GLU B 149 ? LYS B 153 ? GLU B 356 LYS B 360 5 ? 5 HELX_P HELX_P9 AA9 LYS B 207 ? GLN B 212 ? LYS B 414 GLN B 419 1 ? 6 HELX_P HELX_P10 AB1 LEU B 225 ? TYR B 229 ? LEU B 432 TYR B 436 5 ? 5 HELX_P HELX_P11 AB2 LYS D 26 ? MET D 32 ? LYS D 246 MET D 252 1 ? 7 HELX_P HELX_P12 AB3 LEU D 89 ? GLY D 96 ? LEU D 309 GLY D 316 1 ? 8 HELX_P HELX_P13 AB4 SER D 134 ? LYS D 140 ? SER D 354 LYS D 360 5 ? 7 HELX_P HELX_P14 AB5 LYS D 194 ? GLN D 199 ? LYS D 414 GLN D 419 1 ? 6 HELX_P HELX_P15 AB6 LEU D 212 ? TYR D 216 ? LEU D 432 TYR D 436 5 ? 5 HELX_P HELX_P16 AB7 LYS E 39 ? GLU E 45 ? LYS E 246 GLU E 252 1 ? 7 HELX_P HELX_P17 AB8 LEU E 102 ? ASN E 108 ? LEU E 309 ASN E 315 1 ? 7 HELX_P HELX_P18 AB9 SER E 147 ? MET E 151 ? SER E 354 MET E 358 5 ? 5 HELX_P HELX_P19 AC1 LYS E 207 ? GLN E 212 ? LYS E 414 GLN E 419 1 ? 6 HELX_P HELX_P20 AC2 LEU E 225 ? TYR E 229 ? LEU E 432 TYR E 436 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 41 SG ? ? ? 1_555 A CYS 101 SG ? ? A CYS 261 A CYS 321 1_555 ? ? ? ? ? ? ? 2.025 ? disulf2 disulf ? ? A CYS 147 SG ? ? ? 1_555 A CYS 205 SG ? ? A CYS 367 A CYS 425 1_555 ? ? ? ? ? ? ? 2.030 ? disulf3 disulf ? ? B CYS 54 SG ? ? ? 1_555 B CYS 114 SG ? ? B CYS 261 B CYS 321 1_555 ? ? ? ? ? ? ? 2.053 ? disulf4 disulf ? ? B CYS 160 SG ? ? ? 1_555 B CYS 218 SG ? ? B CYS 367 B CYS 425 1_555 ? ? ? ? ? ? ? 2.044 ? disulf5 disulf ? ? C CYS 2 SG ? ? ? 1_555 C CYS 12 SG ? ? C CYS 2 C CYS 12 1_555 ? ? ? ? ? ? ? 2.050 ? disulf6 disulf ? ? D CYS 41 SG ? ? ? 1_555 D CYS 101 SG ? ? D CYS 261 D CYS 321 1_555 ? ? ? ? ? ? ? 2.048 ? disulf7 disulf ? ? D CYS 147 SG ? ? ? 1_555 D CYS 205 SG ? ? D CYS 367 D CYS 425 1_555 ? ? ? ? ? ? ? 2.008 ? disulf8 disulf ? ? E CYS 54 SG ? ? ? 1_555 E CYS 114 SG ? ? E CYS 261 E CYS 321 1_555 ? ? ? ? ? ? ? 2.043 ? disulf9 disulf ? ? E CYS 160 SG ? ? ? 1_555 E CYS 218 SG ? ? E CYS 367 E CYS 425 1_555 ? ? ? ? ? ? ? 2.031 ? disulf10 disulf ? ? F CYS 2 SG ? ? ? 1_555 F CYS 12 SG ? ? F CYS 2 F CYS 12 1_555 ? ? ? ? ? ? ? 2.052 ? covale1 covale one ? A ASN 77 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 297 A NAG 501 1_555 ? ? ? ? ? ? ? 1.431 ? covale2 covale one ? B ASN 90 ND2 ? ? ? 1_555 O NAG . C1 ? ? B ASN 297 B NAG 501 1_555 ? ? ? ? ? ? ? 1.437 ? covale3 covale one ? D ASN 77 ND2 ? ? ? 1_555 W NAG . C1 ? ? D ASN 297 D NAG 501 1_555 ? ? ? ? ? ? ? 1.431 ? covale4 covale one ? E ASN 90 ND2 ? ? ? 1_555 FA NAG . C1 ? ? E ASN 297 E NAG 501 1_555 ? ? ? ? ? ? ? 1.436 ? covale5 covale both ? G NAG . O4 ? ? ? 1_555 H NAG . C1 ? ? A NAG 501 A NAG 502 1_555 ? ? ? ? ? ? ? 1.433 ? covale6 covale one ? G NAG . O6 ? ? ? 1_555 M FUC . C1 ? ? A NAG 501 A FUC 507 1_555 ? ? ? ? ? ? ? 1.437 ? covale7 covale both ? H NAG . O4 ? ? ? 1_555 I BMA . C1 ? ? A NAG 502 A BMA 503 1_555 ? ? ? ? ? ? ? 1.435 ? covale8 covale one ? I BMA . O3 ? ? ? 1_555 N MAN . C1 ? ? A BMA 503 A MAN 508 1_555 ? ? ? ? ? ? ? 1.444 ? covale9 covale one ? I BMA . O6 ? ? ? 1_555 J MAN . C1 ? ? A BMA 503 A MAN 504 1_555 ? ? ? ? ? ? ? 1.435 ? covale10 covale one ? J MAN . O2 ? ? ? 1_555 K NAG . C1 ? ? A MAN 504 A NAG 505 1_555 ? ? ? ? ? ? ? 1.430 ? covale11 covale both ? K NAG . O4 ? ? ? 1_555 L GAL . C1 ? ? A NAG 505 A GAL 506 1_555 ? ? ? ? ? ? ? 1.445 ? covale12 covale both ? O NAG . O4 ? ? ? 1_555 P NAG . C1 ? ? B NAG 501 B NAG 502 1_555 ? ? ? ? ? ? ? 1.434 ? covale13 covale one ? O NAG . O6 ? ? ? 1_555 V FUC . C1 ? ? B NAG 501 B FUC 508 1_555 ? ? ? ? ? ? ? 1.445 ? covale14 covale both ? P NAG . O4 ? ? ? 1_555 Q BMA . C1 ? ? B NAG 502 B BMA 503 1_555 ? ? ? ? ? ? ? 1.449 ? covale15 covale one ? Q BMA . O3 ? ? ? 1_555 U MAN . C1 ? ? B BMA 503 B MAN 507 1_555 ? ? ? ? ? ? ? 1.440 ? covale16 covale one ? Q BMA . O6 ? ? ? 1_555 R MAN . C1 ? ? B BMA 503 B MAN 504 1_555 ? ? ? ? ? ? ? 1.442 ? covale17 covale one ? R MAN . O2 ? ? ? 1_555 S NAG . C1 ? ? B MAN 504 B NAG 505 1_555 ? ? ? ? ? ? ? 1.446 ? covale18 covale both ? S NAG . O4 ? ? ? 1_555 T GAL . C1 ? ? B NAG 505 B GAL 506 1_555 ? ? ? ? ? ? ? 1.445 ? covale19 covale both ? W NAG . O4 ? ? ? 1_555 X NAG . C1 ? ? D NAG 501 D NAG 502 1_555 ? ? ? ? ? ? ? 1.437 ? covale20 covale one ? W NAG . O6 ? ? ? 1_555 CA FUC . C1 ? ? D NAG 501 D FUC 507 1_555 ? ? ? ? ? ? ? 1.439 ? covale21 covale both ? X NAG . O4 ? ? ? 1_555 Y BMA . C1 ? ? D NAG 502 D BMA 503 1_555 ? ? ? ? ? ? ? 1.442 ? covale22 covale one ? Y BMA . O3 ? ? ? 1_555 DA MAN . C1 ? ? D BMA 503 D MAN 508 1_555 ? ? ? ? ? ? ? 1.444 ? covale23 covale one ? Y BMA . O6 ? ? ? 1_555 Z MAN . C1 ? ? D BMA 503 D MAN 504 1_555 ? ? ? ? ? ? ? 1.434 ? covale24 covale one ? Z MAN . O2 ? ? ? 1_555 AA NAG . C1 ? ? D MAN 504 D NAG 505 1_555 ? ? ? ? ? ? ? 1.437 ? covale25 covale both ? AA NAG . O4 ? ? ? 1_555 BA GAL . C1 ? ? D NAG 505 D GAL 506 1_555 ? ? ? ? ? ? ? 1.442 ? covale26 covale both ? FA NAG . O4 ? ? ? 1_555 GA NAG . C1 ? ? E NAG 501 E NAG 502 1_555 ? ? ? ? ? ? ? 1.442 ? covale27 covale one ? FA NAG . O6 ? ? ? 1_555 MA FUC . C1 ? ? E NAG 501 E FUC 508 1_555 ? ? ? ? ? ? ? 1.443 ? covale28 covale both ? GA NAG . O4 ? ? ? 1_555 HA BMA . C1 ? ? E NAG 502 E BMA 503 1_555 ? ? ? ? ? ? ? 1.439 ? covale29 covale one ? HA BMA . O3 ? ? ? 1_555 LA MAN . C1 ? ? E BMA 503 E MAN 507 1_555 ? ? ? ? ? ? ? 1.445 ? covale30 covale one ? HA BMA . O6 ? ? ? 1_555 IA MAN . C1 ? ? E BMA 503 E MAN 504 1_555 ? ? ? ? ? ? ? 1.441 ? covale31 covale one ? IA MAN . O2 ? ? ? 1_555 JA NAG . C1 ? ? E MAN 504 E NAG 505 1_555 ? ? ? ? ? ? ? 1.442 ? covale32 covale both ? JA NAG . O4 ? ? ? 1_555 KA GAL . C1 ? ? E NAG 505 E GAL 506 1_555 ? ? ? ? ? ? ? 1.439 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 TYR 153 A . ? TYR 373 A PRO 154 A ? PRO 374 A 1 -4.52 2 TYR 166 B . ? TYR 373 B PRO 167 B ? PRO 374 B 1 -6.16 3 TYR 153 D . ? TYR 373 D PRO 154 D ? PRO 374 D 1 -9.53 4 TYR 166 E . ? TYR 373 E PRO 167 E ? PRO 374 E 1 -11.33 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 4 ? AA2 ? 4 ? AA3 ? 4 ? AA4 ? 4 ? AA5 ? 4 ? AA6 ? 4 ? AA7 ? 4 ? AA8 ? 4 ? AA9 ? 4 ? AB1 ? 4 ? AB2 ? 4 ? AB3 ? 3 ? AB4 ? 2 ? AB5 ? 4 ? AB6 ? 4 ? AB7 ? 4 ? AB8 ? 4 ? AB9 ? 4 ? AC1 ? 4 ? AC2 ? 4 ? AC3 ? 4 ? AC4 ? 4 ? AC5 ? 4 ? AC6 ? 4 ? AC7 ? 4 ? AC8 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? anti-parallel AA1 3 4 ? anti-parallel AA2 1 2 ? anti-parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA3 1 2 ? anti-parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA4 1 2 ? anti-parallel AA4 2 3 ? anti-parallel AA4 3 4 ? anti-parallel AA5 1 2 ? anti-parallel AA5 2 3 ? anti-parallel AA5 3 4 ? anti-parallel AA6 1 2 ? anti-parallel AA6 2 3 ? anti-parallel AA6 3 4 ? anti-parallel AA7 1 2 ? anti-parallel AA7 2 3 ? anti-parallel AA7 3 4 ? anti-parallel AA8 1 2 ? anti-parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA9 1 2 ? anti-parallel AA9 2 3 ? anti-parallel AA9 3 4 ? anti-parallel AB1 1 2 ? anti-parallel AB1 2 3 ? anti-parallel AB1 3 4 ? anti-parallel AB2 1 2 ? anti-parallel AB2 2 3 ? anti-parallel AB2 3 4 ? anti-parallel AB3 1 2 ? anti-parallel AB3 2 3 ? anti-parallel AB4 1 2 ? anti-parallel AB5 1 2 ? anti-parallel AB5 2 3 ? anti-parallel AB5 3 4 ? anti-parallel AB6 1 2 ? anti-parallel AB6 2 3 ? anti-parallel AB6 3 4 ? anti-parallel AB7 1 2 ? anti-parallel AB7 2 3 ? anti-parallel AB7 3 4 ? anti-parallel AB8 1 2 ? anti-parallel AB8 2 3 ? anti-parallel AB8 3 4 ? anti-parallel AB9 1 2 ? anti-parallel AB9 2 3 ? anti-parallel AB9 3 4 ? anti-parallel AC1 1 2 ? anti-parallel AC1 2 3 ? anti-parallel AC1 3 4 ? anti-parallel AC2 1 2 ? anti-parallel AC2 2 3 ? anti-parallel AC2 3 4 ? anti-parallel AC3 1 2 ? anti-parallel AC3 2 3 ? anti-parallel AC3 3 4 ? anti-parallel AC4 1 2 ? anti-parallel AC4 2 3 ? anti-parallel AC4 3 4 ? anti-parallel AC5 1 2 ? anti-parallel AC5 2 3 ? anti-parallel AC5 3 4 ? anti-parallel AC6 1 2 ? anti-parallel AC6 2 3 ? anti-parallel AC6 3 4 ? anti-parallel AC7 1 2 ? anti-parallel AC7 2 3 ? anti-parallel AC7 3 4 ? anti-parallel AC8 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 SER A 19 ? PHE A 23 ? SER A 239 PHE A 243 AA1 2 GLU A 38 ? SER A 47 ? GLU A 258 SER A 267 AA1 3 THR A 79 ? THR A 87 ? THR A 299 THR A 307 AA1 4 LYS A 68 ? THR A 69 ? LYS A 288 THR A 289 AA2 1 SER A 19 ? PHE A 23 ? SER A 239 PHE A 243 AA2 2 GLU A 38 ? SER A 47 ? GLU A 258 SER A 267 AA2 3 THR A 79 ? THR A 87 ? THR A 299 THR A 307 AA2 4 GLU A 73 ? GLU A 74 ? GLU A 293 GLU A 294 AA3 1 VAL A 62 ? VAL A 64 ? VAL A 282 VAL A 284 AA3 2 LYS A 54 ? VAL A 59 ? LYS A 274 VAL A 279 AA3 3 TYR A 99 ? SER A 104 ? TYR A 319 SER A 324 AA3 4 ILE A 112 ? ILE A 116 ? ILE A 332 ILE A 336 AA4 1 GLN A 127 ? LEU A 131 ? GLN A 347 LEU A 351 AA4 2 GLN A 142 ? PHE A 152 ? GLN A 362 PHE A 372 AA4 3 PHE A 184 ? ASP A 193 ? PHE A 404 ASP A 413 AA4 4 TYR A 171 ? THR A 173 ? TYR A 391 THR A 393 AA5 1 GLN A 127 ? LEU A 131 ? GLN A 347 LEU A 351 AA5 2 GLN A 142 ? PHE A 152 ? GLN A 362 PHE A 372 AA5 3 PHE A 184 ? ASP A 193 ? PHE A 404 ASP A 413 AA5 4 VAL A 177 ? LEU A 178 ? VAL A 397 LEU A 398 AA6 1 GLN A 166 ? PRO A 167 ? GLN A 386 PRO A 387 AA6 2 ALA A 158 ? SER A 163 ? ALA A 378 SER A 383 AA6 3 PHE A 203 ? MET A 208 ? PHE A 423 MET A 428 AA6 4 THR A 217 ? LEU A 221 ? THR A 437 LEU A 441 AA7 1 SER B 32 ? PHE B 36 ? SER B 239 PHE B 243 AA7 2 GLU B 51 ? SER B 60 ? GLU B 258 SER B 267 AA7 3 THR B 92 ? THR B 100 ? THR B 299 THR B 307 AA7 4 LYS B 81 ? THR B 82 ? LYS B 288 THR B 289 AA8 1 SER B 32 ? PHE B 36 ? SER B 239 PHE B 243 AA8 2 GLU B 51 ? SER B 60 ? GLU B 258 SER B 267 AA8 3 THR B 92 ? THR B 100 ? THR B 299 THR B 307 AA8 4 GLU B 86 ? GLN B 88 ? GLU B 293 GLN B 295 AA9 1 VAL B 75 ? VAL B 77 ? VAL B 282 VAL B 284 AA9 2 LYS B 67 ? VAL B 72 ? LYS B 274 VAL B 279 AA9 3 TYR B 112 ? SER B 117 ? TYR B 319 SER B 324 AA9 4 ILE B 125 ? ILE B 129 ? ILE B 332 ILE B 336 AB1 1 GLN B 140 ? LEU B 144 ? GLN B 347 LEU B 351 AB1 2 GLN B 155 ? PHE B 165 ? GLN B 362 PHE B 372 AB1 3 PHE B 197 ? ASP B 206 ? PHE B 404 ASP B 413 AB1 4 TYR B 184 ? THR B 186 ? TYR B 391 THR B 393 AB2 1 GLN B 140 ? LEU B 144 ? GLN B 347 LEU B 351 AB2 2 GLN B 155 ? PHE B 165 ? GLN B 362 PHE B 372 AB2 3 PHE B 197 ? ASP B 206 ? PHE B 404 ASP B 413 AB2 4 VAL B 190 ? LEU B 191 ? VAL B 397 LEU B 398 AB3 1 ALA B 171 ? GLU B 175 ? ALA B 378 GLU B 382 AB3 2 PHE B 216 ? MET B 221 ? PHE B 423 MET B 428 AB3 3 THR B 230 ? LEU B 234 ? THR B 437 LEU B 441 AB4 1 CYS C 2 ? HIS C 5 ? CYS C 2 HIS C 5 AB4 2 GLU C 8 ? CYS C 12 ? GLU C 8 CYS C 12 AB5 1 SER D 19 ? PHE D 23 ? SER D 239 PHE D 243 AB5 2 GLU D 38 ? SER D 47 ? GLU D 258 SER D 267 AB5 3 THR D 79 ? THR D 87 ? THR D 299 THR D 307 AB5 4 LYS D 68 ? THR D 69 ? LYS D 288 THR D 289 AB6 1 SER D 19 ? PHE D 23 ? SER D 239 PHE D 243 AB6 2 GLU D 38 ? SER D 47 ? GLU D 258 SER D 267 AB6 3 THR D 79 ? THR D 87 ? THR D 299 THR D 307 AB6 4 GLU D 73 ? GLU D 74 ? GLU D 293 GLU D 294 AB7 1 VAL D 62 ? VAL D 64 ? VAL D 282 VAL D 284 AB7 2 LYS D 54 ? VAL D 59 ? LYS D 274 VAL D 279 AB7 3 TYR D 99 ? SER D 104 ? TYR D 319 SER D 324 AB7 4 ILE D 112 ? ILE D 116 ? ILE D 332 ILE D 336 AB8 1 GLN D 127 ? LEU D 131 ? GLN D 347 LEU D 351 AB8 2 GLN D 142 ? PHE D 152 ? GLN D 362 PHE D 372 AB8 3 PHE D 184 ? ASP D 193 ? PHE D 404 ASP D 413 AB8 4 TYR D 171 ? THR D 173 ? TYR D 391 THR D 393 AB9 1 GLN D 127 ? LEU D 131 ? GLN D 347 LEU D 351 AB9 2 GLN D 142 ? PHE D 152 ? GLN D 362 PHE D 372 AB9 3 PHE D 184 ? ASP D 193 ? PHE D 404 ASP D 413 AB9 4 VAL D 177 ? LEU D 178 ? VAL D 397 LEU D 398 AC1 1 GLN D 166 ? PRO D 167 ? GLN D 386 PRO D 387 AC1 2 ALA D 158 ? SER D 163 ? ALA D 378 SER D 383 AC1 3 PHE D 203 ? MET D 208 ? PHE D 423 MET D 428 AC1 4 THR D 217 ? LEU D 221 ? THR D 437 LEU D 441 AC2 1 SER E 32 ? PHE E 36 ? SER E 239 PHE E 243 AC2 2 GLU E 51 ? VAL E 59 ? GLU E 258 VAL E 266 AC2 3 TYR E 93 ? THR E 100 ? TYR E 300 THR E 307 AC2 4 LYS E 81 ? THR E 82 ? LYS E 288 THR E 289 AC3 1 SER E 32 ? PHE E 36 ? SER E 239 PHE E 243 AC3 2 GLU E 51 ? VAL E 59 ? GLU E 258 VAL E 266 AC3 3 TYR E 93 ? THR E 100 ? TYR E 300 THR E 307 AC3 4 GLU E 86 ? GLU E 87 ? GLU E 293 GLU E 294 AC4 1 VAL E 75 ? VAL E 77 ? VAL E 282 VAL E 284 AC4 2 LYS E 67 ? VAL E 72 ? LYS E 274 VAL E 279 AC4 3 TYR E 112 ? SER E 117 ? TYR E 319 SER E 324 AC4 4 ILE E 125 ? ILE E 129 ? ILE E 332 ILE E 336 AC5 1 GLN E 140 ? LEU E 144 ? GLN E 347 LEU E 351 AC5 2 GLN E 155 ? PHE E 165 ? GLN E 362 PHE E 372 AC5 3 PHE E 197 ? ASP E 206 ? PHE E 404 ASP E 413 AC5 4 TYR E 184 ? THR E 186 ? TYR E 391 THR E 393 AC6 1 GLN E 140 ? LEU E 144 ? GLN E 347 LEU E 351 AC6 2 GLN E 155 ? PHE E 165 ? GLN E 362 PHE E 372 AC6 3 PHE E 197 ? ASP E 206 ? PHE E 404 ASP E 413 AC6 4 VAL E 190 ? LEU E 191 ? VAL E 397 LEU E 398 AC7 1 GLN E 179 ? PRO E 180 ? GLN E 386 PRO E 387 AC7 2 ALA E 171 ? SER E 176 ? ALA E 378 SER E 383 AC7 3 PHE E 216 ? MET E 221 ? PHE E 423 MET E 428 AC7 4 THR E 230 ? LEU E 234 ? THR E 437 LEU E 441 AC8 1 CYS F 2 ? HIS F 5 ? CYS F 2 HIS F 5 AC8 2 GLU F 8 ? CYS F 12 ? GLU F 8 CYS F 12 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N PHE A 21 ? N PHE A 241 O VAL A 42 ? O VAL A 262 AA1 2 3 N VAL A 46 ? N VAL A 266 O TYR A 80 ? O TYR A 300 AA1 3 4 O VAL A 85 ? O VAL A 305 N LYS A 68 ? N LYS A 288 AA2 1 2 N PHE A 21 ? N PHE A 241 O VAL A 42 ? O VAL A 262 AA2 2 3 N VAL A 46 ? N VAL A 266 O TYR A 80 ? O TYR A 300 AA2 3 4 O ARG A 81 ? O ARG A 301 N GLU A 73 ? N GLU A 293 AA3 1 2 O VAL A 62 ? O VAL A 282 N VAL A 59 ? N VAL A 279 AA3 2 3 N TYR A 58 ? N TYR A 278 O LYS A 100 ? O LYS A 320 AA3 3 4 N VAL A 103 ? N VAL A 323 O ILE A 112 ? O ILE A 332 AA4 1 2 N LEU A 131 ? N LEU A 351 O THR A 146 ? O THR A 366 AA4 2 3 N CYS A 147 ? N CYS A 367 O SER A 188 ? O SER A 408 AA4 3 4 O LYS A 189 ? O LYS A 409 N LYS A 172 ? N LYS A 392 AA5 1 2 N LEU A 131 ? N LEU A 351 O THR A 146 ? O THR A 366 AA5 2 3 N CYS A 147 ? N CYS A 367 O SER A 188 ? O SER A 408 AA5 3 4 O PHE A 185 ? O PHE A 405 N VAL A 177 ? N VAL A 397 AA6 1 2 O GLN A 166 ? O GLN A 386 N SER A 163 ? N SER A 383 AA6 2 3 N GLU A 162 ? N GLU A 382 O SER A 204 ? O SER A 424 AA6 3 4 N CYS A 205 ? N CYS A 425 O LYS A 219 ? O LYS A 439 AA7 1 2 N SER B 32 ? N SER B 239 O VAL B 57 ? O VAL B 264 AA7 2 3 N VAL B 56 ? N VAL B 263 O VAL B 95 ? O VAL B 302 AA7 3 4 O VAL B 98 ? O VAL B 305 N LYS B 81 ? N LYS B 288 AA8 1 2 N SER B 32 ? N SER B 239 O VAL B 57 ? O VAL B 264 AA8 2 3 N VAL B 56 ? N VAL B 263 O VAL B 95 ? O VAL B 302 AA8 3 4 O THR B 92 ? O THR B 299 N GLN B 88 ? N GLN B 295 AA9 1 2 O VAL B 75 ? O VAL B 282 N VAL B 72 ? N VAL B 279 AA9 2 3 N TYR B 71 ? N TYR B 278 O LYS B 113 ? O LYS B 320 AA9 3 4 N VAL B 116 ? N VAL B 323 O ILE B 125 ? O ILE B 332 AB1 1 2 N LEU B 144 ? N LEU B 351 O VAL B 159 ? O VAL B 366 AB1 2 3 N LEU B 158 ? N LEU B 365 O LEU B 203 ? O LEU B 410 AB1 3 4 O PHE B 202 ? O PHE B 409 N LYS B 185 ? N LYS B 392 AB2 1 2 N LEU B 144 ? N LEU B 351 O VAL B 159 ? O VAL B 366 AB2 2 3 N LEU B 158 ? N LEU B 365 O LEU B 203 ? O LEU B 410 AB2 3 4 O PHE B 198 ? O PHE B 405 N VAL B 190 ? N VAL B 397 AB3 1 2 N GLU B 173 ? N GLU B 380 O SER B 219 ? O SER B 426 AB3 2 3 N CYS B 218 ? N CYS B 425 O LYS B 232 ? O LYS B 439 AB4 1 2 N ALA C 3 ? N ALA C 3 O VAL C 10 ? O VAL C 10 AB5 1 2 N PHE D 23 ? N PHE D 243 O THR D 40 ? O THR D 260 AB5 2 3 N VAL D 43 ? N VAL D 263 O VAL D 82 ? O VAL D 302 AB5 3 4 O VAL D 85 ? O VAL D 305 N LYS D 68 ? N LYS D 288 AB6 1 2 N PHE D 23 ? N PHE D 243 O THR D 40 ? O THR D 260 AB6 2 3 N VAL D 43 ? N VAL D 263 O VAL D 82 ? O VAL D 302 AB6 3 4 O ARG D 81 ? O ARG D 301 N GLU D 73 ? N GLU D 293 AB7 1 2 O VAL D 62 ? O VAL D 282 N VAL D 59 ? N VAL D 279 AB7 2 3 N ASN D 56 ? N ASN D 276 O LYS D 102 ? O LYS D 322 AB7 3 4 N VAL D 103 ? N VAL D 323 O ILE D 112 ? O ILE D 332 AB8 1 2 N GLN D 127 ? N GLN D 347 O LYS D 150 ? O LYS D 370 AB8 2 3 N LEU D 145 ? N LEU D 365 O LEU D 190 ? O LEU D 410 AB8 3 4 O LYS D 189 ? O LYS D 409 N LYS D 172 ? N LYS D 392 AB9 1 2 N GLN D 127 ? N GLN D 347 O LYS D 150 ? O LYS D 370 AB9 2 3 N LEU D 145 ? N LEU D 365 O LEU D 190 ? O LEU D 410 AB9 3 4 O PHE D 185 ? O PHE D 405 N VAL D 177 ? N VAL D 397 AC1 1 2 O GLN D 166 ? O GLN D 386 N SER D 163 ? N SER D 383 AC1 2 3 N GLU D 160 ? N GLU D 380 O SER D 206 ? O SER D 426 AC1 3 4 N CYS D 205 ? N CYS D 425 O LYS D 219 ? O LYS D 439 AC2 1 2 N PHE E 34 ? N PHE E 241 O VAL E 55 ? O VAL E 262 AC2 2 3 N VAL E 59 ? N VAL E 266 O TYR E 93 ? O TYR E 300 AC2 3 4 O VAL E 98 ? O VAL E 305 N LYS E 81 ? N LYS E 288 AC3 1 2 N PHE E 34 ? N PHE E 241 O VAL E 55 ? O VAL E 262 AC3 2 3 N VAL E 59 ? N VAL E 266 O TYR E 93 ? O TYR E 300 AC3 3 4 O ARG E 94 ? O ARG E 301 N GLU E 86 ? N GLU E 293 AC4 1 2 O VAL E 75 ? O VAL E 282 N VAL E 72 ? N VAL E 279 AC4 2 3 N ASN E 69 ? N ASN E 276 O LYS E 115 ? O LYS E 322 AC4 3 4 N VAL E 116 ? N VAL E 323 O ILE E 125 ? O ILE E 332 AC5 1 2 N TYR E 142 ? N TYR E 349 O LEU E 161 ? O LEU E 368 AC5 2 3 N LEU E 158 ? N LEU E 365 O LEU E 203 ? O LEU E 410 AC5 3 4 O PHE E 202 ? O PHE E 409 N LYS E 185 ? N LYS E 392 AC6 1 2 N TYR E 142 ? N TYR E 349 O LEU E 161 ? O LEU E 368 AC6 2 3 N LEU E 158 ? N LEU E 365 O LEU E 203 ? O LEU E 410 AC6 3 4 O PHE E 198 ? O PHE E 405 N VAL E 190 ? N VAL E 397 AC7 1 2 O GLN E 179 ? O GLN E 386 N SER E 176 ? N SER E 383 AC7 2 3 N GLU E 173 ? N GLU E 380 O SER E 219 ? O SER E 426 AC7 3 4 N PHE E 216 ? N PHE E 423 O LEU E 234 ? O LEU E 441 AC8 1 2 N ALA F 3 ? N ALA F 3 O VAL F 10 ? O VAL F 10 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software D IOD 509 ? 1 'binding site for residue IOD D 509' AC2 Software A ASN 297 ? 15 'binding site for Poly-Saccharide residues NAG A 501 through MAN A 508 bound to ASN A 297' AC3 Software B ASN 297 ? 14 'binding site for Poly-Saccharide residues NAG B 501 through FUC B 508 bound to ASN B 297' AC4 Software D ASN 297 ? 17 'binding site for Poly-Saccharide residues NAG D 501 through MAN D 508 bound to ASN D 297' AC5 Software E ASN 297 ? 14 'binding site for Poly-Saccharide residues NAG E 501 through FUC E 508 bound to ASN E 297' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 1 HOH NA . ? HOH A 629 . ? 1_554 ? 2 AC2 15 PHE A 21 ? PHE A 241 . ? 1_555 ? 3 AC2 15 PHE A 23 ? PHE A 243 . ? 1_555 ? 4 AC2 15 PRO A 24 ? PRO A 244 . ? 1_555 ? 5 AC2 15 LYS A 26 ? LYS A 246 . ? 1_555 ? 6 AC2 15 GLU A 38 ? GLU A 258 . ? 1_555 ? 7 AC2 15 THR A 40 ? THR A 260 . ? 1_555 ? 8 AC2 15 VAL A 44 ? VAL A 264 . ? 1_555 ? 9 AC2 15 ASP A 45 ? ASP A 265 . ? 1_555 ? 10 AC2 15 GLN A 75 ? GLN A 295 . ? 1_555 ? 11 AC2 15 ASN A 77 ? ASN A 297 . ? 1_555 ? 12 AC2 15 ARG A 81 ? ARG A 301 . ? 1_555 ? 13 AC2 15 HOH NA . ? HOH A 602 . ? 1_555 ? 14 AC2 15 HOH NA . ? HOH A 635 . ? 1_555 ? 15 AC2 15 HOH NA . ? HOH A 637 . ? 1_555 ? 16 AC2 15 ILE D 33 ? ILE D 253 . ? 1_555 ? 17 AC3 14 PHE B 34 ? PHE B 241 . ? 1_555 ? 18 AC3 14 PHE B 36 ? PHE B 243 . ? 1_555 ? 19 AC3 14 PRO B 37 ? PRO B 244 . ? 1_555 ? 20 AC3 14 PRO B 38 ? PRO B 245 . ? 1_555 ? 21 AC3 14 LYS B 39 ? LYS B 246 . ? 1_555 ? 22 AC3 14 ASP B 42 ? ASP B 249 . ? 1_555 ? 23 AC3 14 GLU B 51 ? GLU B 258 . ? 1_555 ? 24 AC3 14 THR B 53 ? THR B 260 . ? 1_555 ? 25 AC3 14 VAL B 57 ? VAL B 264 . ? 1_555 ? 26 AC3 14 ASP B 58 ? ASP B 265 . ? 1_555 ? 27 AC3 14 GLN B 88 ? GLN B 295 . ? 1_555 ? 28 AC3 14 ASN B 90 ? ASN B 297 . ? 1_555 ? 29 AC3 14 ARG B 94 ? ARG B 301 . ? 1_555 ? 30 AC3 14 ALA E 46 ? ALA E 253 . ? 1_665 ? 31 AC4 17 ILE A 33 ? ILE A 253 . ? 1_455 ? 32 AC4 17 PHE D 21 ? PHE D 241 . ? 1_555 ? 33 AC4 17 PHE D 23 ? PHE D 243 . ? 1_555 ? 34 AC4 17 PRO D 24 ? PRO D 244 . ? 1_555 ? 35 AC4 17 LYS D 26 ? LYS D 246 . ? 1_555 ? 36 AC4 17 GLU D 38 ? GLU D 258 . ? 1_555 ? 37 AC4 17 THR D 40 ? THR D 260 . ? 1_555 ? 38 AC4 17 VAL D 44 ? VAL D 264 . ? 1_555 ? 39 AC4 17 ASP D 45 ? ASP D 265 . ? 1_555 ? 40 AC4 17 GLN D 75 ? GLN D 295 . ? 1_555 ? 41 AC4 17 ASN D 77 ? ASN D 297 . ? 1_555 ? 42 AC4 17 THR D 79 ? THR D 299 . ? 1_555 ? 43 AC4 17 ARG D 81 ? ARG D 301 . ? 1_555 ? 44 AC4 17 HOH QA . ? HOH D 602 . ? 1_555 ? 45 AC4 17 HOH QA . ? HOH D 621 . ? 1_555 ? 46 AC4 17 HOH QA . ? HOH D 637 . ? 1_555 ? 47 AC4 17 HOH QA . ? HOH D 649 . ? 1_555 ? 48 AC5 14 PHE E 34 ? PHE E 241 . ? 1_555 ? 49 AC5 14 PHE E 36 ? PHE E 243 . ? 1_555 ? 50 AC5 14 PRO E 37 ? PRO E 244 . ? 1_555 ? 51 AC5 14 PRO E 38 ? PRO E 245 . ? 1_555 ? 52 AC5 14 LYS E 39 ? LYS E 246 . ? 1_555 ? 53 AC5 14 ASP E 42 ? ASP E 249 . ? 1_555 ? 54 AC5 14 GLU E 51 ? GLU E 258 . ? 1_555 ? 55 AC5 14 THR E 53 ? THR E 260 . ? 1_555 ? 56 AC5 14 VAL E 57 ? VAL E 264 . ? 1_555 ? 57 AC5 14 ASP E 58 ? ASP E 265 . ? 1_555 ? 58 AC5 14 GLN E 88 ? GLN E 295 . ? 1_555 ? 59 AC5 14 ASN E 90 ? ASN E 297 . ? 1_555 ? 60 AC5 14 ARG E 94 ? ARG E 301 . ? 1_555 ? 61 AC5 14 HOH RA . ? HOH E 622 . ? 1_555 ? # _atom_sites.entry_id 5DJC _atom_sites.fract_transf_matrix[1][1] 0.016600 _atom_sites.fract_transf_matrix[1][2] -0.000090 _atom_sites.fract_transf_matrix[1][3] -0.002718 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.014957 _atom_sites.fract_transf_matrix[2][3] -0.001269 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.013974 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C I N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLY A 1 17 ? -7.863 10.864 -22.044 1.00 51.19 ? 237 GLY A N 1 ATOM 2 C CA . GLY A 1 17 ? -6.765 9.956 -21.597 1.00 47.19 ? 237 GLY A CA 1 ATOM 3 C C . GLY A 1 17 ? -6.863 9.507 -20.142 1.00 46.00 ? 237 GLY A C 1 ATOM 4 O O . GLY A 1 17 ? -7.841 9.811 -19.450 1.00 44.85 ? 237 GLY A O 1 ATOM 5 N N . PRO A 1 18 ? -5.853 8.756 -19.674 1.00 37.45 ? 238 PRO A N 1 ATOM 6 C CA . PRO A 1 18 ? -5.751 8.257 -18.297 1.00 35.65 ? 238 PRO A CA 1 ATOM 7 C C . PRO A 1 18 ? -5.640 9.362 -17.254 1.00 35.63 ? 238 PRO A C 1 ATOM 8 O O . PRO A 1 18 ? -5.224 10.464 -17.576 1.00 43.38 ? 238 PRO A O 1 ATOM 9 C CB . PRO A 1 18 ? -4.460 7.442 -18.322 1.00 36.77 ? 238 PRO A CB 1 ATOM 10 C CG . PRO A 1 18 ? -4.344 6.985 -19.741 1.00 40.81 ? 238 PRO A CG 1 ATOM 11 C CD . PRO A 1 18 ? -4.870 8.118 -20.566 1.00 39.74 ? 238 PRO A CD 1 ATOM 12 N N . SER A 1 19 ? -6.014 9.061 -16.015 1.00 33.04 ? 239 SER A N 1 ATOM 13 C CA . SER A 1 19 ? -5.882 10.012 -14.915 1.00 39.46 ? 239 SER A CA 1 ATOM 14 C C . SER A 1 19 ? -5.106 9.386 -13.759 1.00 36.14 ? 239 SER A C 1 ATOM 15 O O . SER A 1 19 ? -5.220 8.184 -13.495 1.00 34.14 ? 239 SER A O 1 ATOM 16 C CB . SER A 1 19 ? -7.254 10.493 -14.435 1.00 42.31 ? 239 SER A CB 1 ATOM 17 O OG . SER A 1 19 ? -8.054 10.899 -15.526 1.00 55.35 ? 239 SER A OG 1 ATOM 18 N N . VAL A 1 20 ? -4.327 10.211 -13.065 1.00 30.03 ? 240 VAL A N 1 ATOM 19 C CA . VAL A 1 20 ? -3.378 9.718 -12.079 1.00 31.15 ? 240 VAL A CA 1 ATOM 20 C C . VAL A 1 20 ? -3.722 10.276 -10.697 1.00 29.80 ? 240 VAL A C 1 ATOM 21 O O . VAL A 1 20 ? -4.014 11.459 -10.562 1.00 30.05 ? 240 VAL A O 1 ATOM 22 C CB . VAL A 1 20 ? -1.926 10.089 -12.471 1.00 27.11 ? 240 VAL A CB 1 ATOM 23 C CG1 . VAL A 1 20 ? -0.925 9.504 -11.489 1.00 23.19 ? 240 VAL A CG1 1 ATOM 24 C CG2 . VAL A 1 20 ? -1.606 9.597 -13.879 1.00 27.94 ? 240 VAL A CG2 1 ATOM 25 N N . PHE A 1 21 ? -3.687 9.421 -9.679 1.00 30.53 ? 241 PHE A N 1 ATOM 26 C CA . PHE A 1 21 ? -3.922 9.854 -8.296 1.00 31.67 ? 241 PHE A CA 1 ATOM 27 C C . PHE A 1 21 ? -2.834 9.320 -7.378 1.00 34.22 ? 241 PHE A C 1 ATOM 28 O O . PHE A 1 21 ? -2.526 8.122 -7.374 1.00 36.99 ? 241 PHE A O 1 ATOM 29 C CB . PHE A 1 21 ? -5.315 9.428 -7.825 1.00 34.64 ? 241 PHE A CB 1 ATOM 30 C CG . PHE A 1 21 ? -6.420 9.988 -8.665 1.00 40.90 ? 241 PHE A CG 1 ATOM 31 C CD1 . PHE A 1 21 ? -6.872 11.288 -8.462 1.00 40.35 ? 241 PHE A CD1 1 ATOM 32 C CD2 . PHE A 1 21 ? -6.979 9.234 -9.698 1.00 40.70 ? 241 PHE A CD2 1 ATOM 33 C CE1 . PHE A 1 21 ? -7.879 11.823 -9.260 1.00 51.40 ? 241 PHE A CE1 1 ATOM 34 C CE2 . PHE A 1 21 ? -7.989 9.762 -10.493 1.00 47.04 ? 241 PHE A CE2 1 ATOM 35 C CZ . PHE A 1 21 ? -8.441 11.057 -10.275 1.00 48.57 ? 241 PHE A CZ 1 ATOM 36 N N . LEU A 1 22 ? -2.231 10.219 -6.618 1.00 32.72 ? 242 LEU A N 1 ATOM 37 C CA . LEU A 1 22 ? -1.094 9.852 -5.807 1.00 31.59 ? 242 LEU A CA 1 ATOM 38 C C . LEU A 1 22 ? -1.467 9.984 -4.343 1.00 30.29 ? 242 LEU A C 1 ATOM 39 O O . LEU A 1 22 ? -1.837 11.063 -3.888 1.00 28.47 ? 242 LEU A O 1 ATOM 40 C CB . LEU A 1 22 ? 0.137 10.699 -6.168 1.00 30.01 ? 242 LEU A CB 1 ATOM 41 C CG . LEU A 1 22 ? 1.464 10.284 -5.510 1.00 29.09 ? 242 LEU A CG 1 ATOM 42 C CD1 . LEU A 1 22 ? 1.864 8.847 -5.813 1.00 25.81 ? 242 LEU A CD1 1 ATOM 43 C CD2 . LEU A 1 22 ? 2.591 11.230 -5.891 1.00 30.67 ? 242 LEU A CD2 1 ATOM 44 N N . PHE A 1 23 ? -1.367 8.871 -3.625 1.00 30.35 ? 243 PHE A N 1 ATOM 45 C CA . PHE A 1 23 ? -1.850 8.768 -2.247 1.00 33.49 ? 243 PHE A CA 1 ATOM 46 C C . PHE A 1 23 ? -0.733 8.606 -1.218 1.00 30.29 ? 243 PHE A C 1 ATOM 47 O O . PHE A 1 23 ? 0.182 7.822 -1.430 1.00 27.15 ? 243 PHE A O 1 ATOM 48 C CB . PHE A 1 23 ? -2.806 7.573 -2.152 1.00 32.69 ? 243 PHE A CB 1 ATOM 49 C CG . PHE A 1 23 ? -4.039 7.732 -2.979 1.00 26.92 ? 243 PHE A CG 1 ATOM 50 C CD1 . PHE A 1 23 ? -5.100 8.515 -2.525 1.00 28.97 ? 243 PHE A CD1 1 ATOM 51 C CD2 . PHE A 1 23 ? -4.137 7.124 -4.227 1.00 33.94 ? 243 PHE A CD2 1 ATOM 52 C CE1 . PHE A 1 23 ? -6.244 8.671 -3.293 1.00 33.36 ? 243 PHE A CE1 1 ATOM 53 C CE2 . PHE A 1 23 ? -5.280 7.269 -4.998 1.00 30.27 ? 243 PHE A CE2 1 ATOM 54 C CZ . PHE A 1 23 ? -6.334 8.042 -4.533 1.00 30.10 ? 243 PHE A CZ 1 ATOM 55 N N . PRO A 1 24 ? -0.812 9.340 -0.091 1.00 33.88 ? 244 PRO A N 1 ATOM 56 C CA . PRO A 1 24 ? 0.181 9.213 0.972 1.00 32.95 ? 244 PRO A CA 1 ATOM 57 C C . PRO A 1 24 ? 0.047 7.889 1.736 1.00 33.36 ? 244 PRO A C 1 ATOM 58 O O . PRO A 1 24 ? -0.947 7.193 1.572 1.00 31.61 ? 244 PRO A O 1 ATOM 59 C CB . PRO A 1 24 ? -0.157 10.391 1.894 1.00 40.60 ? 244 PRO A CB 1 ATOM 60 C CG . PRO A 1 24 ? -1.611 10.614 1.689 1.00 34.80 ? 244 PRO A CG 1 ATOM 61 C CD . PRO A 1 24 ? -1.831 10.356 0.233 1.00 36.48 ? 244 PRO A CD 1 ATOM 62 N N . PRO A 1 25 ? 1.048 7.533 2.564 1.00 34.52 ? 245 PRO A N 1 ATOM 63 C CA . PRO A 1 25 ? 0.863 6.358 3.426 1.00 35.74 ? 245 PRO A CA 1 ATOM 64 C C . PRO A 1 25 ? -0.080 6.658 4.590 1.00 31.67 ? 245 PRO A C 1 ATOM 65 O O . PRO A 1 25 ? -0.415 7.810 4.822 1.00 26.30 ? 245 PRO A O 1 ATOM 66 C CB . PRO A 1 25 ? 2.279 6.056 3.924 1.00 33.08 ? 245 PRO A CB 1 ATOM 67 C CG . PRO A 1 25 ? 3.015 7.340 3.808 1.00 35.37 ? 245 PRO A CG 1 ATOM 68 C CD . PRO A 1 25 ? 2.417 8.071 2.641 1.00 33.62 ? 245 PRO A CD 1 ATOM 69 N N . LYS A 1 26 ? -0.518 5.622 5.296 1.00 31.21 ? 246 LYS A N 1 ATOM 70 C CA . LYS A 1 26 ? -1.437 5.795 6.414 1.00 31.31 ? 246 LYS A CA 1 ATOM 71 C C . LYS A 1 26 ? -0.676 6.397 7.593 1.00 26.12 ? 246 LYS A C 1 ATOM 72 O O . LYS A 1 26 ? 0.433 5.976 7.896 1.00 23.44 ? 246 LYS A O 1 ATOM 73 C CB . LYS A 1 26 ? -2.044 4.455 6.841 1.00 32.80 ? 246 LYS A CB 1 ATOM 74 C CG . LYS A 1 26 ? -3.058 3.852 5.887 1.00 39.92 ? 246 LYS A CG 1 ATOM 75 C CD . LYS A 1 26 ? -4.366 4.638 5.854 1.00 43.29 ? 246 LYS A CD 1 ATOM 76 C CE . LYS A 1 26 ? -5.298 4.092 4.780 1.00 45.88 ? 246 LYS A CE 1 ATOM 77 N NZ . LYS A 1 26 ? -4.729 4.217 3.410 1.00 39.84 ? 246 LYS A NZ 1 ATOM 78 N N . PRO A 1 27 ? -1.258 7.394 8.256 1.00 31.56 ? 247 PRO A N 1 ATOM 79 C CA . PRO A 1 27 ? -0.574 7.881 9.452 1.00 28.91 ? 247 PRO A CA 1 ATOM 80 C C . PRO A 1 27 ? 0.065 6.769 10.287 1.00 25.10 ? 247 PRO A C 1 ATOM 81 O O . PRO A 1 27 ? 1.266 6.819 10.547 1.00 35.67 ? 247 PRO A O 1 ATOM 82 C CB . PRO A 1 27 ? -1.686 8.590 10.193 1.00 28.60 ? 247 PRO A CB 1 ATOM 83 C CG . PRO A 1 27 ? -2.471 9.216 9.073 1.00 31.74 ? 247 PRO A CG 1 ATOM 84 C CD . PRO A 1 27 ? -2.452 8.204 7.947 1.00 31.27 ? 247 PRO A CD 1 ATOM 85 N N . LYS A 1 28 ? -0.713 5.756 10.651 1.00 30.84 ? 248 LYS A N 1 ATOM 86 C CA . LYS A 1 28 ? -0.225 4.625 11.452 1.00 34.67 ? 248 LYS A CA 1 ATOM 87 C C . LYS A 1 28 ? 1.018 3.929 10.918 1.00 31.75 ? 248 LYS A C 1 ATOM 88 O O . LYS A 1 28 ? 1.886 3.529 11.696 1.00 24.57 ? 248 LYS A O 1 ATOM 89 C CB . LYS A 1 28 ? -1.321 3.582 11.632 1.00 35.99 ? 248 LYS A CB 1 ATOM 90 C CG . LYS A 1 28 ? -1.939 3.618 13.010 1.00 43.51 ? 248 LYS A CG 1 ATOM 91 C CD . LYS A 1 28 ? -3.002 2.547 13.167 1.00 43.05 ? 248 LYS A CD 1 ATOM 92 C CE . LYS A 1 28 ? -2.460 1.305 13.842 1.00 36.70 ? 248 LYS A CE 1 ATOM 93 N NZ . LYS A 1 28 ? -3.587 0.435 14.302 1.00 45.54 ? 248 LYS A NZ 1 ATOM 94 N N . ASP A 1 29 ? 1.081 3.754 9.600 1.00 24.01 ? 249 ASP A N 1 ATOM 95 C CA . ASP A 1 29 ? 2.192 3.075 8.972 1.00 27.32 ? 249 ASP A CA 1 ATOM 96 C C . ASP A 1 29 ? 3.459 3.923 9.070 1.00 31.49 ? 249 ASP A C 1 ATOM 97 O O . ASP A 1 29 ? 4.550 3.395 9.310 1.00 37.28 ? 249 ASP A O 1 ATOM 98 C CB . ASP A 1 29 ? 1.851 2.754 7.511 1.00 34.85 ? 249 ASP A CB 1 ATOM 99 C CG . ASP A 1 29 ? 0.748 1.703 7.382 1.00 47.40 ? 249 ASP A CG 1 ATOM 100 O OD1 . ASP A 1 29 ? 0.269 1.172 8.411 1.00 50.32 ? 249 ASP A OD1 1 ATOM 101 O OD2 . ASP A 1 29 ? 0.357 1.397 6.241 1.00 61.29 ? 249 ASP A OD2 1 ATOM 102 N N . THR A 1 30 ? 3.307 5.238 8.907 1.00 30.39 ? 250 THR A N 1 ATOM 103 C CA . THR A 1 30 ? 4.443 6.143 8.970 1.00 30.23 ? 250 THR A CA 1 ATOM 104 C C . THR A 1 30 ? 4.958 6.212 10.394 1.00 29.49 ? 250 THR A C 1 ATOM 105 O O . THR A 1 30 ? 6.139 6.494 10.618 1.00 24.87 ? 250 THR A O 1 ATOM 106 C CB . THR A 1 30 ? 4.096 7.577 8.505 1.00 30.81 ? 250 THR A CB 1 ATOM 107 O OG1 . THR A 1 30 ? 3.239 8.197 9.465 1.00 30.99 ? 250 THR A OG1 1 ATOM 108 C CG2 . THR A 1 30 ? 3.414 7.574 7.145 1.00 29.50 ? 250 THR A CG2 1 ATOM 109 N N . LEU A 1 31 ? 4.072 5.927 11.350 1.00 32.65 ? 251 LEU A N 1 ATOM 110 C CA . LEU A 1 31 ? 4.342 6.205 12.774 1.00 29.58 ? 251 LEU A CA 1 ATOM 111 C C . LEU A 1 31 ? 4.753 5.015 13.628 1.00 31.33 ? 251 LEU A C 1 ATOM 112 O O . LEU A 1 31 ? 5.236 5.185 14.758 1.00 37.54 ? 251 LEU A O 1 ATOM 113 C CB . LEU A 1 31 ? 3.138 6.896 13.411 1.00 26.85 ? 251 LEU A CB 1 ATOM 114 C CG . LEU A 1 31 ? 2.957 8.378 13.066 1.00 27.12 ? 251 LEU A CG 1 ATOM 115 C CD1 . LEU A 1 31 ? 1.715 8.960 13.721 1.00 30.88 ? 251 LEU A CD1 1 ATOM 116 C CD2 . LEU A 1 31 ? 4.174 9.169 13.498 1.00 24.21 ? 251 LEU A CD2 1 ATOM 117 N N . MET A 1 32 ? 4.535 3.814 13.110 1.00 27.80 ? 252 MET A N 1 ATOM 118 C CA . MET A 1 32 ? 4.887 2.601 13.835 1.00 31.20 ? 252 MET A CA 1 ATOM 119 C C . MET A 1 32 ? 6.008 1.927 13.083 1.00 29.89 ? 252 MET A C 1 ATOM 120 O O . MET A 1 32 ? 5.832 1.521 11.919 1.00 28.49 ? 252 MET A O 1 ATOM 121 C CB . MET A 1 32 ? 3.689 1.651 13.973 1.00 30.92 ? 252 MET A CB 1 ATOM 122 C CG . MET A 1 32 ? 2.579 2.134 14.887 1.00 30.75 ? 252 MET A CG 1 ATOM 123 S SD . MET A 1 32 ? 1.122 1.053 14.911 1.00 35.76 ? 252 MET A SD 1 ATOM 124 C CE . MET A 1 32 ? 1.768 -0.506 15.521 1.00 28.81 ? 252 MET A CE 1 ATOM 125 N N . ILE A 1 33 ? 7.164 1.825 13.737 1.00 26.56 ? 253 ILE A N 1 ATOM 126 C CA . ILE A 1 33 ? 8.344 1.185 13.137 1.00 30.91 ? 253 ILE A CA 1 ATOM 127 C C . ILE A 1 33 ? 8.106 -0.284 12.745 1.00 27.54 ? 253 ILE A C 1 ATOM 128 O O . ILE A 1 33 ? 8.857 -0.846 11.961 1.00 25.15 ? 253 ILE A O 1 ATOM 129 C CB . ILE A 1 33 ? 9.569 1.286 14.071 1.00 32.80 ? 253 ILE A CB 1 ATOM 130 C CG1 . ILE A 1 33 ? 10.895 1.305 13.286 1.00 29.72 ? 253 ILE A CG1 1 ATOM 131 C CG2 . ILE A 1 33 ? 9.564 0.132 15.072 1.00 32.80 ? 253 ILE A CG2 1 ATOM 132 C CD1 . ILE A 1 33 ? 10.997 2.340 12.188 1.00 26.06 ? 253 ILE A CD1 1 ATOM 133 N N . SER A 1 34 ? 7.068 -0.905 13.291 1.00 31.97 ? 254 SER A N 1 ATOM 134 C CA . SER A 1 34 ? 6.761 -2.297 12.950 1.00 36.66 ? 254 SER A CA 1 ATOM 135 C C . SER A 1 34 ? 5.910 -2.428 11.684 1.00 35.68 ? 254 SER A C 1 ATOM 136 O O . SER A 1 34 ? 5.660 -3.539 11.217 1.00 37.37 ? 254 SER A O 1 ATOM 137 C CB . SER A 1 34 ? 6.100 -3.015 14.125 1.00 30.79 ? 254 SER A CB 1 ATOM 138 O OG . SER A 1 34 ? 5.103 -2.195 14.701 1.00 38.67 ? 254 SER A OG 1 ATOM 139 N N . ARG A 1 35 ? 5.491 -1.292 11.126 1.00 32.72 ? 255 ARG A N 1 ATOM 140 C CA . ARG A 1 35 ? 4.674 -1.268 9.915 1.00 32.36 ? 255 ARG A CA 1 ATOM 141 C C . ARG A 1 35 ? 5.435 -0.742 8.690 1.00 36.45 ? 255 ARG A C 1 ATOM 142 O O . ARG A 1 35 ? 6.473 -0.106 8.832 1.00 41.94 ? 255 ARG A O 1 ATOM 143 C CB . ARG A 1 35 ? 3.393 -0.466 10.169 1.00 30.29 ? 255 ARG A CB 1 ATOM 144 C CG . ARG A 1 35 ? 2.465 -1.173 11.139 1.00 34.00 ? 255 ARG A CG 1 ATOM 145 C CD . ARG A 1 35 ? 1.017 -0.877 10.844 1.00 43.17 ? 255 ARG A CD 1 ATOM 146 N NE . ARG A 1 35 ? 0.170 -1.922 11.402 1.00 54.02 ? 255 ARG A NE 1 ATOM 147 C CZ . ARG A 1 35 ? -1.148 -1.838 11.519 1.00 53.45 ? 255 ARG A CZ 1 ATOM 148 N NH1 . ARG A 1 35 ? -1.792 -0.749 11.123 1.00 60.60 ? 255 ARG A NH1 1 ATOM 149 N NH2 . ARG A 1 35 ? -1.822 -2.851 12.040 1.00 71.31 ? 255 ARG A NH2 1 ATOM 150 N N . THR A 1 36 ? 4.916 -1.016 7.495 1.00 36.48 ? 256 THR A N 1 ATOM 151 C CA . THR A 1 36 ? 5.561 -0.588 6.246 1.00 35.73 ? 256 THR A CA 1 ATOM 152 C C . THR A 1 36 ? 4.759 0.517 5.557 1.00 31.91 ? 256 THR A C 1 ATOM 153 O O . THR A 1 36 ? 3.701 0.257 5.006 1.00 39.70 ? 256 THR A O 1 ATOM 154 C CB . THR A 1 36 ? 5.740 -1.754 5.258 1.00 37.11 ? 256 THR A CB 1 ATOM 155 O OG1 . THR A 1 36 ? 6.053 -2.951 5.978 1.00 50.87 ? 256 THR A OG1 1 ATOM 156 C CG2 . THR A 1 36 ? 6.861 -1.467 4.282 1.00 34.76 ? 256 THR A CG2 1 ATOM 157 N N . PRO A 1 37 ? 5.258 1.759 5.598 1.00 29.78 ? 257 PRO A N 1 ATOM 158 C CA . PRO A 1 37 ? 4.562 2.845 4.909 1.00 32.39 ? 257 PRO A CA 1 ATOM 159 C C . PRO A 1 37 ? 4.873 2.815 3.411 1.00 27.64 ? 257 PRO A C 1 ATOM 160 O O . PRO A 1 37 ? 6.011 2.556 3.026 1.00 24.61 ? 257 PRO A O 1 ATOM 161 C CB . PRO A 1 37 ? 5.153 4.087 5.554 1.00 27.34 ? 257 PRO A CB 1 ATOM 162 C CG . PRO A 1 37 ? 6.539 3.679 5.900 1.00 32.38 ? 257 PRO A CG 1 ATOM 163 C CD . PRO A 1 37 ? 6.485 2.224 6.263 1.00 28.68 ? 257 PRO A CD 1 ATOM 164 N N . GLU A 1 38 ? 3.858 3.038 2.588 1.00 32.70 ? 258 GLU A N 1 ATOM 165 C CA . GLU A 1 38 ? 4.029 3.053 1.129 1.00 31.92 ? 258 GLU A CA 1 ATOM 166 C C . GLU A 1 38 ? 3.232 4.187 0.489 1.00 32.76 ? 258 GLU A C 1 ATOM 167 O O . GLU A 1 38 ? 2.183 4.581 1.002 1.00 35.49 ? 258 GLU A O 1 ATOM 168 C CB . GLU A 1 38 ? 3.656 1.699 0.522 1.00 33.14 ? 258 GLU A CB 1 ATOM 169 C CG . GLU A 1 38 ? 2.280 1.179 0.908 1.00 44.26 ? 258 GLU A CG 1 ATOM 170 C CD . GLU A 1 38 ? 2.064 -0.277 0.544 1.00 47.85 ? 258 GLU A CD 1 ATOM 171 O OE1 . GLU A 1 38 ? 0.987 -0.596 0.003 1.00 63.55 ? 258 GLU A OE1 1 ATOM 172 O OE2 . GLU A 1 38 ? 2.968 -1.104 0.783 1.00 52.15 ? 258 GLU A OE2 1 ATOM 173 N N . VAL A 1 39 ? 3.756 4.741 -0.600 1.00 29.46 ? 259 VAL A N 1 ATOM 174 C CA . VAL A 1 39 ? 3.000 5.697 -1.408 1.00 29.69 ? 259 VAL A CA 1 ATOM 175 C C . VAL A 1 39 ? 2.516 4.956 -2.647 1.00 30.40 ? 259 VAL A C 1 ATOM 176 O O . VAL A 1 39 ? 3.205 4.072 -3.166 1.00 25.46 ? 259 VAL A O 1 ATOM 177 C CB . VAL A 1 39 ? 3.806 6.973 -1.788 1.00 31.31 ? 259 VAL A CB 1 ATOM 178 C CG1 . VAL A 1 39 ? 4.401 7.617 -0.556 1.00 29.92 ? 259 VAL A CG1 1 ATOM 179 C CG2 . VAL A 1 39 ? 4.914 6.664 -2.773 1.00 29.80 ? 259 VAL A CG2 1 ATOM 180 N N . THR A 1 40 ? 1.323 5.312 -3.105 1.00 31.46 ? 260 THR A N 1 ATOM 181 C CA . THR A 1 40 ? 0.638 4.532 -4.116 1.00 32.78 ? 260 THR A CA 1 ATOM 182 C C . THR A 1 40 ? 0.277 5.436 -5.295 1.00 26.83 ? 260 THR A C 1 ATOM 183 O O . THR A 1 40 ? -0.370 6.460 -5.117 1.00 29.26 ? 260 THR A O 1 ATOM 184 C CB . THR A 1 40 ? -0.632 3.898 -3.512 1.00 36.69 ? 260 THR A CB 1 ATOM 185 O OG1 . THR A 1 40 ? -0.345 3.401 -2.196 1.00 35.46 ? 260 THR A OG1 1 ATOM 186 C CG2 . THR A 1 40 ? -1.150 2.765 -4.387 1.00 30.85 ? 260 THR A CG2 1 ATOM 187 N N . CYS A 1 41 ? 0.705 5.059 -6.488 1.00 26.01 ? 261 CYS A N 1 ATOM 188 C CA . CYS A 1 41 ? 0.396 5.846 -7.691 1.00 28.91 ? 261 CYS A CA 1 ATOM 189 C C . CYS A 1 41 ? -0.649 5.098 -8.484 1.00 27.68 ? 261 CYS A C 1 ATOM 190 O O . CYS A 1 41 ? -0.342 4.089 -9.112 1.00 25.97 ? 261 CYS A O 1 ATOM 191 C CB . CYS A 1 41 ? 1.655 6.064 -8.537 1.00 26.65 ? 261 CYS A CB 1 ATOM 192 S SG . CYS A 1 41 ? 1.601 7.343 -9.831 1.00 31.19 ? 261 CYS A SG 1 ATOM 193 N N . VAL A 1 42 ? -1.885 5.596 -8.442 1.00 30.12 ? 262 VAL A N 1 ATOM 194 C CA . VAL A 1 42 ? -3.018 4.958 -9.118 1.00 24.44 ? 262 VAL A CA 1 ATOM 195 C C . VAL A 1 42 ? -3.303 5.661 -10.443 1.00 28.95 ? 262 VAL A C 1 ATOM 196 O O . VAL A 1 42 ? -3.474 6.872 -10.494 1.00 32.61 ? 262 VAL A O 1 ATOM 197 C CB . VAL A 1 42 ? -4.269 4.941 -8.223 1.00 27.65 ? 262 VAL A CB 1 ATOM 198 C CG1 . VAL A 1 42 ? -5.424 4.205 -8.894 1.00 23.69 ? 262 VAL A CG1 1 ATOM 199 C CG2 . VAL A 1 42 ? -3.936 4.299 -6.871 1.00 27.77 ? 262 VAL A CG2 1 ATOM 200 N N . VAL A 1 43 ? -3.305 4.881 -11.512 1.00 24.55 ? 263 VAL A N 1 ATOM 201 C CA . VAL A 1 43 ? -3.652 5.354 -12.840 1.00 29.39 ? 263 VAL A CA 1 ATOM 202 C C . VAL A 1 43 ? -4.976 4.703 -13.226 1.00 25.90 ? 263 VAL A C 1 ATOM 203 O O . VAL A 1 43 ? -5.080 3.469 -13.268 1.00 26.01 ? 263 VAL A O 1 ATOM 204 C CB . VAL A 1 43 ? -2.580 4.968 -13.869 1.00 32.08 ? 263 VAL A CB 1 ATOM 205 C CG1 . VAL A 1 43 ? -2.837 5.673 -15.193 1.00 33.96 ? 263 VAL A CG1 1 ATOM 206 C CG2 . VAL A 1 43 ? -1.194 5.325 -13.346 1.00 33.39 ? 263 VAL A CG2 1 ATOM 207 N N . VAL A 1 44 ? -5.992 5.531 -13.467 1.00 25.31 ? 264 VAL A N 1 ATOM 208 C CA . VAL A 1 44 ? -7.284 5.029 -13.914 1.00 28.86 ? 264 VAL A CA 1 ATOM 209 C C . VAL A 1 44 ? -7.461 5.377 -15.388 1.00 30.77 ? 264 VAL A C 1 ATOM 210 O O . VAL A 1 44 ? -6.569 5.955 -15.990 1.00 30.85 ? 264 VAL A O 1 ATOM 211 C CB . VAL A 1 44 ? -8.447 5.586 -13.087 1.00 29.83 ? 264 VAL A CB 1 ATOM 212 C CG1 . VAL A 1 44 ? -8.290 5.205 -11.614 1.00 27.95 ? 264 VAL A CG1 1 ATOM 213 C CG2 . VAL A 1 44 ? -8.551 7.088 -13.260 1.00 36.54 ? 264 VAL A CG2 1 ATOM 214 N N . ASP A 1 45 ? -8.601 5.005 -15.960 1.00 30.42 ? 265 ASP A N 1 ATOM 215 C CA . ASP A 1 45 ? -8.914 5.294 -17.362 1.00 31.03 ? 265 ASP A CA 1 ATOM 216 C C . ASP A 1 45 ? -7.822 4.882 -18.342 1.00 32.77 ? 265 ASP A C 1 ATOM 217 O O . ASP A 1 45 ? -7.637 5.507 -19.393 1.00 40.08 ? 265 ASP A O 1 ATOM 218 C CB . ASP A 1 45 ? -9.319 6.759 -17.530 1.00 32.58 ? 265 ASP A CB 1 ATOM 219 C CG . ASP A 1 45 ? -10.652 7.046 -16.902 1.00 37.46 ? 265 ASP A CG 1 ATOM 220 O OD1 . ASP A 1 45 ? -11.387 6.064 -16.656 1.00 39.27 ? 265 ASP A OD1 1 ATOM 221 O OD2 . ASP A 1 45 ? -10.962 8.230 -16.642 1.00 45.30 ? 265 ASP A OD2 1 ATOM 222 N N . VAL A 1 46 ? -7.091 3.833 -17.979 1.00 34.48 ? 266 VAL A N 1 ATOM 223 C CA . VAL A 1 46 ? -6.140 3.211 -18.878 1.00 35.76 ? 266 VAL A CA 1 ATOM 224 C C . VAL A 1 46 ? -6.959 2.373 -19.843 1.00 34.96 ? 266 VAL A C 1 ATOM 225 O O . VAL A 1 46 ? -7.801 1.585 -19.412 1.00 37.06 ? 266 VAL A O 1 ATOM 226 C CB . VAL A 1 46 ? -5.136 2.323 -18.116 1.00 32.67 ? 266 VAL A CB 1 ATOM 227 C CG1 . VAL A 1 46 ? -4.240 1.567 -19.088 1.00 33.68 ? 266 VAL A CG1 1 ATOM 228 C CG2 . VAL A 1 46 ? -4.300 3.171 -17.178 1.00 33.71 ? 266 VAL A CG2 1 ATOM 229 N N . SER A 1 47 ? -6.717 2.561 -21.140 1.00 39.11 ? 267 SER A N 1 ATOM 230 C CA . SER A 1 47 ? -7.516 1.931 -22.191 1.00 36.90 ? 267 SER A CA 1 ATOM 231 C C . SER A 1 47 ? -7.071 0.509 -22.499 1.00 48.00 ? 267 SER A C 1 ATOM 232 O O . SER A 1 47 ? -5.906 0.137 -22.280 1.00 44.30 ? 267 SER A O 1 ATOM 233 C CB . SER A 1 47 ? -7.466 2.771 -23.474 1.00 36.18 ? 267 SER A CB 1 ATOM 234 O OG . SER A 1 47 ? -6.204 2.659 -24.108 1.00 41.26 ? 267 SER A OG 1 ATOM 235 N N . HIS A 1 48 ? -8.008 -0.272 -23.035 1.00 42.64 ? 268 HIS A N 1 ATOM 236 C CA . HIS A 1 48 ? -7.733 -1.631 -23.474 1.00 42.78 ? 268 HIS A CA 1 ATOM 237 C C . HIS A 1 48 ? -6.747 -1.686 -24.593 1.00 44.37 ? 268 HIS A C 1 ATOM 238 O O . HIS A 1 48 ? -6.018 -2.671 -24.734 1.00 44.67 ? 268 HIS A O 1 ATOM 239 C CB . HIS A 1 48 ? -9.028 -2.324 -23.873 1.00 40.36 ? 268 HIS A CB 1 ATOM 240 C CG . HIS A 1 48 ? -9.730 -2.972 -22.720 1.00 45.20 ? 268 HIS A CG 1 ATOM 241 N ND1 . HIS A 1 48 ? -10.119 -2.279 -21.632 1.00 46.43 ? 268 HIS A ND1 1 ATOM 242 C CD2 . HIS A 1 48 ? -10.086 -4.296 -22.493 1.00 52.55 ? 268 HIS A CD2 1 ATOM 243 C CE1 . HIS A 1 48 ? -10.700 -3.114 -20.753 1.00 50.62 ? 268 HIS A CE1 1 ATOM 244 N NE2 . HIS A 1 48 ? -10.682 -4.349 -21.281 1.00 58.18 ? 268 HIS A NE2 1 ATOM 245 N N . GLU A 1 49 ? -6.722 -0.617 -25.388 1.00 48.38 ? 269 GLU A N 1 ATOM 246 C CA . GLU A 1 49 ? -5.890 -0.509 -26.582 1.00 44.97 ? 269 GLU A CA 1 ATOM 247 C C . GLU A 1 49 ? -4.416 -0.309 -26.226 1.00 45.93 ? 269 GLU A C 1 ATOM 248 O O . GLU A 1 49 ? -3.533 -0.852 -26.894 1.00 43.74 ? 269 GLU A O 1 ATOM 249 C CB . GLU A 1 49 ? -6.384 0.641 -27.473 1.00 56.47 ? 269 GLU A CB 1 ATOM 250 C CG . GLU A 1 49 ? -7.741 0.416 -28.144 1.00 63.18 ? 269 GLU A CG 1 ATOM 251 C CD . GLU A 1 49 ? -8.927 0.448 -27.179 1.00 68.93 ? 269 GLU A CD 1 ATOM 252 O OE1 . GLU A 1 49 ? -8.990 1.334 -26.286 1.00 48.26 ? 269 GLU A OE1 1 ATOM 253 O OE2 . GLU A 1 49 ? -9.812 -0.424 -27.320 1.00 70.04 ? 269 GLU A OE2 1 ATOM 254 N N . ASP A 1 50 ? -4.157 0.472 -25.175 1.00 44.10 ? 270 ASP A N 1 ATOM 255 C CA . ASP A 1 50 ? -2.792 0.710 -24.691 1.00 35.78 ? 270 ASP A CA 1 ATOM 256 C C . ASP A 1 50 ? -2.727 0.589 -23.156 1.00 37.81 ? 270 ASP A C 1 ATOM 257 O O . ASP A 1 50 ? -2.666 1.607 -22.448 1.00 29.01 ? 270 ASP A O 1 ATOM 258 C CB . ASP A 1 50 ? -2.267 2.080 -25.161 1.00 36.33 ? 270 ASP A CB 1 ATOM 259 C CG . ASP A 1 50 ? -2.055 2.156 -26.685 1.00 47.48 ? 270 ASP A CG 1 ATOM 260 O OD1 . ASP A 1 50 ? -2.708 2.998 -27.335 1.00 47.58 ? 270 ASP A OD1 1 ATOM 261 O OD2 . ASP A 1 50 ? -1.234 1.390 -27.239 1.00 50.38 ? 270 ASP A OD2 1 ATOM 262 N N . PRO A 1 51 ? -2.742 -0.656 -22.636 1.00 36.98 ? 271 PRO A N 1 ATOM 263 C CA . PRO A 1 51 ? -2.728 -0.868 -21.189 1.00 31.53 ? 271 PRO A CA 1 ATOM 264 C C . PRO A 1 51 ? -1.368 -0.608 -20.546 1.00 35.94 ? 271 PRO A C 1 ATOM 265 O O . PRO A 1 51 ? -1.271 -0.498 -19.326 1.00 33.80 ? 271 PRO A O 1 ATOM 266 C CB . PRO A 1 51 ? -3.097 -2.342 -21.047 1.00 34.98 ? 271 PRO A CB 1 ATOM 267 C CG . PRO A 1 51 ? -2.635 -2.971 -22.313 1.00 36.89 ? 271 PRO A CG 1 ATOM 268 C CD . PRO A 1 51 ? -2.818 -1.930 -23.379 1.00 35.98 ? 271 PRO A CD 1 ATOM 269 N N . GLU A 1 52 ? -0.337 -0.492 -21.372 1.00 38.40 ? 272 GLU A N 1 ATOM 270 C CA . GLU A 1 52 ? 1.028 -0.358 -20.893 1.00 38.61 ? 272 GLU A CA 1 ATOM 271 C C . GLU A 1 52 ? 1.292 1.015 -20.281 1.00 38.86 ? 272 GLU A C 1 ATOM 272 O O . GLU A 1 52 ? 1.032 2.057 -20.893 1.00 41.70 ? 272 GLU A O 1 ATOM 273 C CB . GLU A 1 52 ? 2.014 -0.675 -22.022 1.00 37.40 ? 272 GLU A CB 1 ATOM 274 C CG . GLU A 1 52 ? 1.848 -2.085 -22.578 1.00 39.38 ? 272 GLU A CG 1 ATOM 275 C CD . GLU A 1 52 ? 0.929 -2.181 -23.799 1.00 38.04 ? 272 GLU A CD 1 ATOM 276 O OE1 . GLU A 1 52 ? 0.899 -3.267 -24.404 1.00 44.86 ? 272 GLU A OE1 1 ATOM 277 O OE2 . GLU A 1 52 ? 0.242 -1.200 -24.165 1.00 35.60 ? 272 GLU A OE2 1 ATOM 278 N N . VAL A 1 53 ? 1.785 1.002 -19.050 1.00 39.40 ? 273 VAL A N 1 ATOM 279 C CA . VAL A 1 53 ? 2.081 2.223 -18.314 1.00 34.29 ? 273 VAL A CA 1 ATOM 280 C C . VAL A 1 53 ? 3.521 2.158 -17.801 1.00 34.40 ? 273 VAL A C 1 ATOM 281 O O . VAL A 1 53 ? 3.963 1.119 -17.319 1.00 37.76 ? 273 VAL A O 1 ATOM 282 C CB . VAL A 1 53 ? 1.101 2.410 -17.139 1.00 33.90 ? 273 VAL A CB 1 ATOM 283 C CG1 . VAL A 1 53 ? 1.460 3.643 -16.322 1.00 37.67 ? 273 VAL A CG1 1 ATOM 284 C CG2 . VAL A 1 53 ? -0.331 2.518 -17.643 1.00 29.50 ? 273 VAL A CG2 1 ATOM 285 N N . LYS A 1 54 ? 4.257 3.259 -17.931 1.00 34.28 ? 274 LYS A N 1 ATOM 286 C CA . LYS A 1 54 ? 5.594 3.351 -17.370 1.00 28.22 ? 274 LYS A CA 1 ATOM 287 C C . LYS A 1 54 ? 5.568 4.292 -16.172 1.00 33.67 ? 274 LYS A C 1 ATOM 288 O O . LYS A 1 54 ? 5.050 5.407 -16.256 1.00 31.88 ? 274 LYS A O 1 ATOM 289 C CB . LYS A 1 54 ? 6.592 3.838 -18.414 1.00 35.06 ? 274 LYS A CB 1 ATOM 290 C CG . LYS A 1 54 ? 8.042 3.844 -17.950 1.00 45.45 ? 274 LYS A CG 1 ATOM 291 C CD . LYS A 1 54 ? 8.962 4.364 -19.053 1.00 56.57 ? 274 LYS A CD 1 ATOM 292 C CE . LYS A 1 54 ? 10.431 4.382 -18.638 1.00 60.18 ? 274 LYS A CE 1 ATOM 293 N NZ . LYS A 1 54 ? 11.042 3.022 -18.562 1.00 60.91 ? 274 LYS A NZ 1 ATOM 294 N N . PHE A 1 55 ? 6.095 3.812 -15.052 1.00 31.46 ? 275 PHE A N 1 ATOM 295 C CA . PHE A 1 55 ? 6.281 4.632 -13.872 1.00 30.49 ? 275 PHE A CA 1 ATOM 296 C C . PHE A 1 55 ? 7.748 4.996 -13.738 1.00 31.04 ? 275 PHE A C 1 ATOM 297 O O . PHE A 1 55 ? 8.629 4.172 -13.979 1.00 32.68 ? 275 PHE A O 1 ATOM 298 C CB . PHE A 1 55 ? 5.836 3.885 -12.618 1.00 31.67 ? 275 PHE A CB 1 ATOM 299 C CG . PHE A 1 55 ? 4.371 3.549 -12.596 1.00 32.75 ? 275 PHE A CG 1 ATOM 300 C CD1 . PHE A 1 55 ? 3.928 2.284 -12.965 1.00 30.59 ? 275 PHE A CD1 1 ATOM 301 C CD2 . PHE A 1 55 ? 3.435 4.495 -12.199 1.00 32.24 ? 275 PHE A CD2 1 ATOM 302 C CE1 . PHE A 1 55 ? 2.578 1.973 -12.943 1.00 36.17 ? 275 PHE A CE1 1 ATOM 303 C CE2 . PHE A 1 55 ? 2.081 4.190 -12.175 1.00 33.21 ? 275 PHE A CE2 1 ATOM 304 C CZ . PHE A 1 55 ? 1.651 2.929 -12.550 1.00 32.98 ? 275 PHE A CZ 1 ATOM 305 N N . ASN A 1 56 ? 7.987 6.257 -13.402 1.00 31.45 ? 276 ASN A N 1 ATOM 306 C CA . ASN A 1 56 ? 9.258 6.718 -12.885 1.00 29.33 ? 276 ASN A CA 1 ATOM 307 C C . ASN A 1 56 ? 8.942 7.333 -11.538 1.00 30.36 ? 276 ASN A C 1 ATOM 308 O O . ASN A 1 56 ? 7.925 8.016 -11.390 1.00 35.52 ? 276 ASN A O 1 ATOM 309 C CB . ASN A 1 56 ? 9.871 7.777 -13.794 1.00 29.67 ? 276 ASN A CB 1 ATOM 310 C CG . ASN A 1 56 ? 10.326 7.215 -15.118 1.00 33.31 ? 276 ASN A CG 1 ATOM 311 O OD1 . ASN A 1 56 ? 9.600 7.270 -16.112 1.00 38.67 ? 276 ASN A OD1 1 ATOM 312 N ND2 . ASN A 1 56 ? 11.534 6.668 -15.143 1.00 37.38 ? 276 ASN A ND2 1 ATOM 313 N N . TRP A 1 57 ? 9.796 7.072 -10.558 1.00 30.13 ? 277 TRP A N 1 ATOM 314 C CA . TRP A 1 57 ? 9.615 7.586 -9.199 1.00 25.94 ? 277 TRP A CA 1 ATOM 315 C C . TRP A 1 57 ? 10.776 8.462 -8.814 1.00 33.33 ? 277 TRP A C 1 ATOM 316 O O . TRP A 1 57 ? 11.906 8.202 -9.220 1.00 29.84 ? 277 TRP A O 1 ATOM 317 C CB . TRP A 1 57 ? 9.511 6.419 -8.230 1.00 24.83 ? 277 TRP A CB 1 ATOM 318 C CG . TRP A 1 57 ? 8.169 5.717 -8.229 1.00 27.28 ? 277 TRP A CG 1 ATOM 319 C CD1 . TRP A 1 57 ? 7.796 4.564 -8.926 1.00 25.72 ? 277 TRP A CD1 1 ATOM 320 C CD2 . TRP A 1 57 ? 6.975 6.104 -7.469 1.00 28.37 ? 277 TRP A CD2 1 ATOM 321 N NE1 . TRP A 1 57 ? 6.491 4.228 -8.653 1.00 26.42 ? 277 TRP A NE1 1 ATOM 322 C CE2 . TRP A 1 57 ? 5.947 5.106 -7.779 1.00 27.40 ? 277 TRP A CE2 1 ATOM 323 C CE3 . TRP A 1 57 ? 6.671 7.138 -6.579 1.00 27.71 ? 277 TRP A CE3 1 ATOM 324 C CZ2 . TRP A 1 57 ? 4.685 5.163 -7.224 1.00 27.95 ? 277 TRP A CZ2 1 ATOM 325 C CZ3 . TRP A 1 57 ? 5.389 7.181 -6.021 1.00 31.29 ? 277 TRP A CZ3 1 ATOM 326 C CH2 . TRP A 1 57 ? 4.424 6.211 -6.328 1.00 29.07 ? 277 TRP A CH2 1 ATOM 327 N N . TYR A 1 58 ? 10.513 9.510 -8.026 1.00 40.14 ? 278 TYR A N 1 ATOM 328 C CA . TYR A 1 58 ? 11.558 10.431 -7.567 1.00 32.18 ? 278 TYR A CA 1 ATOM 329 C C . TYR A 1 58 ? 11.378 10.823 -6.099 1.00 32.50 ? 278 TYR A C 1 ATOM 330 O O . TYR A 1 58 ? 10.268 11.121 -5.657 1.00 31.40 ? 278 TYR A O 1 ATOM 331 C CB . TYR A 1 58 ? 11.604 11.685 -8.451 1.00 32.99 ? 278 TYR A CB 1 ATOM 332 C CG . TYR A 1 58 ? 11.672 11.385 -9.944 1.00 33.79 ? 278 TYR A CG 1 ATOM 333 C CD1 . TYR A 1 58 ? 10.507 11.152 -10.686 1.00 31.63 ? 278 TYR A CD1 1 ATOM 334 C CD2 . TYR A 1 58 ? 12.895 11.332 -10.614 1.00 32.19 ? 278 TYR A CD2 1 ATOM 335 C CE1 . TYR A 1 58 ? 10.560 10.871 -12.051 1.00 33.24 ? 278 TYR A CE1 1 ATOM 336 C CE2 . TYR A 1 58 ? 12.954 11.047 -11.982 1.00 34.81 ? 278 TYR A CE2 1 ATOM 337 C CZ . TYR A 1 58 ? 11.785 10.819 -12.694 1.00 33.14 ? 278 TYR A CZ 1 ATOM 338 O OH . TYR A 1 58 ? 11.830 10.538 -14.049 1.00 40.74 ? 278 TYR A OH 1 ATOM 339 N N . VAL A 1 59 ? 12.471 10.800 -5.342 1.00 32.26 ? 279 VAL A N 1 ATOM 340 C CA . VAL A 1 59 ? 12.463 11.250 -3.947 1.00 36.40 ? 279 VAL A CA 1 ATOM 341 C C . VAL A 1 59 ? 13.331 12.491 -3.866 1.00 36.09 ? 279 VAL A C 1 ATOM 342 O O . VAL A 1 59 ? 14.544 12.421 -4.081 1.00 38.71 ? 279 VAL A O 1 ATOM 343 C CB . VAL A 1 59 ? 12.982 10.170 -2.973 1.00 35.43 ? 279 VAL A CB 1 ATOM 344 C CG1 . VAL A 1 59 ? 12.852 10.637 -1.531 1.00 35.15 ? 279 VAL A CG1 1 ATOM 345 C CG2 . VAL A 1 59 ? 12.236 8.861 -3.172 1.00 34.97 ? 279 VAL A CG2 1 ATOM 346 N N . ASP A 1 60 ? 12.697 13.627 -3.575 1.00 40.13 ? 280 ASP A N 1 ATOM 347 C CA . ASP A 1 60 ? 13.358 14.937 -3.602 1.00 34.40 ? 280 ASP A CA 1 ATOM 348 C C . ASP A 1 60 ? 14.141 15.156 -4.896 1.00 41.57 ? 280 ASP A C 1 ATOM 349 O O . ASP A 1 60 ? 15.239 15.706 -4.881 1.00 45.90 ? 280 ASP A O 1 ATOM 350 C CB . ASP A 1 60 ? 14.263 15.124 -2.378 1.00 39.62 ? 280 ASP A CB 1 ATOM 351 C CG . ASP A 1 60 ? 13.488 15.489 -1.123 1.00 34.83 ? 280 ASP A CG 1 ATOM 352 O OD1 . ASP A 1 60 ? 12.291 15.824 -1.213 1.00 36.68 ? 280 ASP A OD1 1 ATOM 353 O OD2 . ASP A 1 60 ? 14.082 15.447 -0.033 1.00 53.74 ? 280 ASP A OD2 1 ATOM 354 N N . GLY A 1 61 ? 13.570 14.711 -6.012 1.00 37.20 ? 281 GLY A N 1 ATOM 355 C CA . GLY A 1 61 ? 14.177 14.919 -7.323 1.00 42.24 ? 281 GLY A CA 1 ATOM 356 C C . GLY A 1 61 ? 15.004 13.759 -7.842 1.00 39.55 ? 281 GLY A C 1 ATOM 357 O O . GLY A 1 61 ? 15.245 13.661 -9.041 1.00 46.74 ? 281 GLY A O 1 ATOM 358 N N . VAL A 1 62 ? 15.441 12.881 -6.943 1.00 45.23 ? 282 VAL A N 1 ATOM 359 C CA . VAL A 1 62 ? 16.337 11.764 -7.290 1.00 45.45 ? 282 VAL A CA 1 ATOM 360 C C . VAL A 1 62 ? 15.548 10.498 -7.624 1.00 42.34 ? 282 VAL A C 1 ATOM 361 O O . VAL A 1 62 ? 14.785 10.006 -6.787 1.00 38.75 ? 282 VAL A O 1 ATOM 362 C CB . VAL A 1 62 ? 17.334 11.468 -6.131 1.00 48.63 ? 282 VAL A CB 1 ATOM 363 C CG1 . VAL A 1 62 ? 18.156 10.207 -6.402 1.00 39.02 ? 282 VAL A CG1 1 ATOM 364 C CG2 . VAL A 1 62 ? 18.244 12.666 -5.878 1.00 40.72 ? 282 VAL A CG2 1 ATOM 365 N N . GLU A 1 63 ? 15.733 9.972 -8.838 1.00 40.04 ? 283 GLU A N 1 ATOM 366 C CA . GLU A 1 63 ? 15.059 8.736 -9.248 1.00 36.55 ? 283 GLU A CA 1 ATOM 367 C C . GLU A 1 63 ? 15.448 7.559 -8.361 1.00 36.70 ? 283 GLU A C 1 ATOM 368 O O . GLU A 1 63 ? 16.625 7.361 -8.075 1.00 40.32 ? 283 GLU A O 1 ATOM 369 C CB . GLU A 1 63 ? 15.318 8.408 -10.731 1.00 37.62 ? 283 GLU A CB 1 ATOM 370 C CG . GLU A 1 63 ? 14.428 7.286 -11.264 1.00 39.56 ? 283 GLU A CG 1 ATOM 371 C CD . GLU A 1 63 ? 14.371 7.191 -12.785 1.00 38.18 ? 283 GLU A CD 1 ATOM 372 O OE1 . GLU A 1 63 ? 15.065 7.957 -13.473 1.00 38.75 ? 283 GLU A OE1 1 ATOM 373 O OE2 . GLU A 1 63 ? 13.611 6.342 -13.300 1.00 41.56 ? 283 GLU A OE2 1 ATOM 374 N N . VAL A 1 64 ? 14.439 6.820 -7.897 1.00 34.96 ? 284 VAL A N 1 ATOM 375 C CA . VAL A 1 64 ? 14.612 5.550 -7.183 1.00 32.09 ? 284 VAL A CA 1 ATOM 376 C C . VAL A 1 64 ? 13.936 4.464 -8.017 1.00 37.53 ? 284 VAL A C 1 ATOM 377 O O . VAL A 1 64 ? 13.076 4.771 -8.840 1.00 41.10 ? 284 VAL A O 1 ATOM 378 C CB . VAL A 1 64 ? 14.030 5.561 -5.741 1.00 35.13 ? 284 VAL A CB 1 ATOM 379 C CG1 . VAL A 1 64 ? 14.839 6.475 -4.820 1.00 28.96 ? 284 VAL A CG1 1 ATOM 380 C CG2 . VAL A 1 64 ? 12.546 5.941 -5.724 1.00 29.73 ? 284 VAL A CG2 1 ATOM 381 N N . HIS A 1 65 ? 14.315 3.205 -7.799 1.00 39.23 ? 285 HIS A N 1 ATOM 382 C CA . HIS A 1 65 ? 13.941 2.117 -8.707 1.00 37.81 ? 285 HIS A CA 1 ATOM 383 C C . HIS A 1 65 ? 13.306 0.923 -8.021 1.00 41.17 ? 285 HIS A C 1 ATOM 384 O O . HIS A 1 65 ? 13.131 -0.122 -8.644 1.00 40.80 ? 285 HIS A O 1 ATOM 385 C CB . HIS A 1 65 ? 15.168 1.665 -9.511 1.00 42.49 ? 285 HIS A CB 1 ATOM 386 C CG . HIS A 1 65 ? 15.839 2.776 -10.302 1.00 47.84 ? 285 HIS A CG 1 ATOM 387 N ND1 . HIS A 1 65 ? 16.649 3.691 -9.729 1.00 48.36 ? 285 HIS A ND1 1 ATOM 388 C CD2 . HIS A 1 65 ? 15.804 3.082 -11.666 1.00 48.87 ? 285 HIS A CD2 1 ATOM 389 C CE1 . HIS A 1 65 ? 17.099 4.546 -10.669 1.00 45.38 ? 285 HIS A CE1 1 ATOM 390 N NE2 . HIS A 1 65 ? 16.582 4.172 -11.855 1.00 45.75 ? 285 HIS A NE2 1 ATOM 391 N N . ASN A 1 66 ? 12.945 1.066 -6.744 1.00 31.29 ? 286 ASN A N 1 ATOM 392 C CA . ASN A 1 66 ? 12.406 -0.046 -5.953 1.00 33.66 ? 286 ASN A CA 1 ATOM 393 C C . ASN A 1 66 ? 10.870 -0.144 -5.899 1.00 37.00 ? 286 ASN A C 1 ATOM 394 O O . ASN A 1 66 ? 10.310 -0.872 -5.060 1.00 30.47 ? 286 ASN A O 1 ATOM 395 C CB . ASN A 1 66 ? 12.955 0.012 -4.530 1.00 31.74 ? 286 ASN A CB 1 ATOM 396 C CG . ASN A 1 66 ? 12.622 1.312 -3.836 1.00 37.76 ? 286 ASN A CG 1 ATOM 397 O OD1 . ASN A 1 66 ? 12.711 2.386 -4.435 1.00 42.25 ? 286 ASN A OD1 1 ATOM 398 N ND2 . ASN A 1 66 ? 12.242 1.229 -2.561 1.00 41.46 ? 286 ASN A ND2 1 ATOM 399 N N . ALA A 1 67 ? 10.191 0.577 -6.787 1.00 36.93 ? 287 ALA A N 1 ATOM 400 C CA . ALA A 1 67 ? 8.736 0.511 -6.852 1.00 32.03 ? 287 ALA A CA 1 ATOM 401 C C . ALA A 1 67 ? 8.325 -0.802 -7.472 1.00 36.38 ? 287 ALA A C 1 ATOM 402 O O . ALA A 1 67 ? 9.067 -1.377 -8.260 1.00 39.11 ? 287 ALA A O 1 ATOM 403 C CB . ALA A 1 67 ? 8.176 1.658 -7.656 1.00 23.01 ? 287 ALA A CB 1 ATOM 404 N N . LYS A 1 68 ? 7.134 -1.260 -7.106 1.00 37.80 ? 288 LYS A N 1 ATOM 405 C CA . LYS A 1 68 ? 6.609 -2.536 -7.557 1.00 41.53 ? 288 LYS A CA 1 ATOM 406 C C . LYS A 1 68 ? 5.218 -2.320 -8.126 1.00 35.49 ? 288 LYS A C 1 ATOM 407 O O . LYS A 1 68 ? 4.368 -1.722 -7.481 1.00 30.92 ? 288 LYS A O 1 ATOM 408 C CB . LYS A 1 68 ? 6.562 -3.539 -6.393 1.00 39.32 ? 288 LYS A CB 1 ATOM 409 C CG . LYS A 1 68 ? 7.911 -4.132 -6.024 1.00 42.71 ? 288 LYS A CG 1 ATOM 410 C CD . LYS A 1 68 ? 7.743 -5.380 -5.170 1.00 59.73 ? 288 LYS A CD 1 ATOM 411 C CE . LYS A 1 68 ? 8.981 -6.264 -5.231 1.00 58.84 ? 288 LYS A CE 1 ATOM 412 N NZ . LYS A 1 68 ? 8.772 -7.557 -4.520 1.00 63.30 ? 288 LYS A NZ 1 ATOM 413 N N . THR A 1 69 ? 4.999 -2.785 -9.348 1.00 34.63 ? 289 THR A N 1 ATOM 414 C CA . THR A 1 69 ? 3.696 -2.683 -9.982 1.00 30.53 ? 289 THR A CA 1 ATOM 415 C C . THR A 1 69 ? 2.770 -3.768 -9.462 1.00 27.76 ? 289 THR A C 1 ATOM 416 O O . THR A 1 69 ? 3.125 -4.951 -9.442 1.00 28.54 ? 289 THR A O 1 ATOM 417 C CB . THR A 1 69 ? 3.820 -2.836 -11.501 1.00 35.71 ? 289 THR A CB 1 ATOM 418 O OG1 . THR A 1 69 ? 4.775 -1.888 -11.988 1.00 31.99 ? 289 THR A OG1 1 ATOM 419 C CG2 . THR A 1 69 ? 2.481 -2.605 -12.173 1.00 32.99 ? 289 THR A CG2 1 ATOM 420 N N . LYS A 1 70 ? 1.585 -3.364 -9.029 1.00 27.78 ? 290 LYS A N 1 ATOM 421 C CA . LYS A 1 70 ? 0.599 -4.313 -8.548 1.00 30.15 ? 290 LYS A CA 1 ATOM 422 C C . LYS A 1 70 ? -0.091 -5.038 -9.708 1.00 30.20 ? 290 LYS A C 1 ATOM 423 O O . LYS A 1 70 ? 0.063 -4.639 -10.861 1.00 30.87 ? 290 LYS A O 1 ATOM 424 C CB . LYS A 1 70 ? -0.394 -3.631 -7.605 1.00 31.86 ? 290 LYS A CB 1 ATOM 425 C CG . LYS A 1 70 ? -0.069 -3.901 -6.141 1.00 44.58 ? 290 LYS A CG 1 ATOM 426 C CD . LYS A 1 70 ? -1.174 -3.447 -5.205 1.00 42.82 ? 290 LYS A CD 1 ATOM 427 C CE . LYS A 1 70 ? -1.586 -4.568 -4.261 1.00 55.42 ? 290 LYS A CE 1 ATOM 428 N NZ . LYS A 1 70 ? -0.447 -5.088 -3.451 1.00 59.97 ? 290 LYS A NZ 1 ATOM 429 N N . PRO A 1 71 ? -0.814 -6.139 -9.418 1.00 35.36 ? 291 PRO A N 1 ATOM 430 C CA . PRO A 1 71 ? -1.544 -6.802 -10.513 1.00 38.34 ? 291 PRO A CA 1 ATOM 431 C C . PRO A 1 71 ? -2.535 -5.849 -11.201 1.00 36.84 ? 291 PRO A C 1 ATOM 432 O O . PRO A 1 71 ? -3.254 -5.110 -10.534 1.00 33.26 ? 291 PRO A O 1 ATOM 433 C CB . PRO A 1 71 ? -2.288 -7.944 -9.807 1.00 37.29 ? 291 PRO A CB 1 ATOM 434 C CG . PRO A 1 71 ? -1.509 -8.205 -8.557 1.00 35.62 ? 291 PRO A CG 1 ATOM 435 C CD . PRO A 1 71 ? -0.911 -6.887 -8.147 1.00 30.67 ? 291 PRO A CD 1 ATOM 436 N N . ARG A 1 72 ? -2.541 -5.857 -12.528 1.00 32.35 ? 292 ARG A N 1 ATOM 437 C CA . ARG A 1 72 ? -3.471 -5.054 -13.298 1.00 30.01 ? 292 ARG A CA 1 ATOM 438 C C . ARG A 1 72 ? -4.903 -5.536 -13.070 1.00 34.05 ? 292 ARG A C 1 ATOM 439 O O . ARG A 1 72 ? -5.152 -6.744 -13.008 1.00 31.95 ? 292 ARG A O 1 ATOM 440 C CB . ARG A 1 72 ? -3.130 -5.144 -14.779 1.00 27.10 ? 292 ARG A CB 1 ATOM 441 C CG . ARG A 1 72 ? -3.820 -4.089 -15.627 1.00 31.41 ? 292 ARG A CG 1 ATOM 442 C CD . ARG A 1 72 ? -3.496 -4.292 -17.099 1.00 28.05 ? 292 ARG A CD 1 ATOM 443 N NE . ARG A 1 72 ? -4.020 -5.562 -17.578 1.00 30.59 ? 292 ARG A NE 1 ATOM 444 C CZ . ARG A 1 72 ? -3.831 -6.046 -18.803 1.00 32.86 ? 292 ARG A CZ 1 ATOM 445 N NH1 . ARG A 1 72 ? -3.106 -5.375 -19.696 1.00 31.16 ? 292 ARG A NH1 1 ATOM 446 N NH2 . ARG A 1 72 ? -4.367 -7.209 -19.129 1.00 27.03 ? 292 ARG A NH2 1 ATOM 447 N N . GLU A 1 73 ? -5.832 -4.584 -12.962 1.00 34.38 ? 293 GLU A N 1 ATOM 448 C CA . GLU A 1 73 ? -7.212 -4.874 -12.585 1.00 40.17 ? 293 GLU A CA 1 ATOM 449 C C . GLU A 1 73 ? -8.215 -4.343 -13.615 1.00 40.35 ? 293 GLU A C 1 ATOM 450 O O . GLU A 1 73 ? -8.309 -3.131 -13.843 1.00 34.81 ? 293 GLU A O 1 ATOM 451 C CB . GLU A 1 73 ? -7.506 -4.281 -11.200 1.00 43.04 ? 293 GLU A CB 1 ATOM 452 C CG . GLU A 1 73 ? -8.147 -5.247 -10.211 1.00 58.08 ? 293 GLU A CG 1 ATOM 453 C CD . GLU A 1 73 ? -7.163 -6.257 -9.635 1.00 65.32 ? 293 GLU A CD 1 ATOM 454 O OE1 . GLU A 1 73 ? -6.782 -6.113 -8.450 1.00 57.92 ? 293 GLU A OE1 1 ATOM 455 O OE2 . GLU A 1 73 ? -6.765 -7.195 -10.363 1.00 58.12 ? 293 GLU A OE2 1 ATOM 456 N N . GLU A 1 74 ? -8.946 -5.266 -14.240 1.00 45.12 ? 294 GLU A N 1 ATOM 457 C CA . GLU A 1 74 ? -10.054 -4.945 -15.146 1.00 42.75 ? 294 GLU A CA 1 ATOM 458 C C . GLU A 1 74 ? -11.199 -4.304 -14.373 1.00 38.41 ? 294 GLU A C 1 ATOM 459 O O . GLU A 1 74 ? -11.649 -4.843 -13.366 1.00 43.07 ? 294 GLU A O 1 ATOM 460 C CB . GLU A 1 74 ? -10.544 -6.222 -15.839 1.00 54.43 ? 294 GLU A CB 1 ATOM 461 C CG . GLU A 1 74 ? -11.846 -6.079 -16.610 1.00 58.09 ? 294 GLU A CG 1 ATOM 462 C CD . GLU A 1 74 ? -11.700 -5.199 -17.828 1.00 47.09 ? 294 GLU A CD 1 ATOM 463 O OE1 . GLU A 1 74 ? -12.099 -4.021 -17.753 1.00 49.39 ? 294 GLU A OE1 1 ATOM 464 O OE2 . GLU A 1 74 ? -11.172 -5.681 -18.849 1.00 55.15 ? 294 GLU A OE2 1 ATOM 465 N N . GLN A 1 75 ? -11.666 -3.153 -14.848 1.00 41.43 ? 295 GLN A N 1 ATOM 466 C CA . GLN A 1 75 ? -12.656 -2.354 -14.113 1.00 38.42 ? 295 GLN A CA 1 ATOM 467 C C . GLN A 1 75 ? -14.103 -2.577 -14.567 1.00 42.95 ? 295 GLN A C 1 ATOM 468 O O . GLN A 1 75 ? -15.035 -2.292 -13.815 1.00 45.86 ? 295 GLN A O 1 ATOM 469 C CB . GLN A 1 75 ? -12.290 -0.864 -14.173 1.00 34.23 ? 295 GLN A CB 1 ATOM 470 C CG . GLN A 1 75 ? -10.997 -0.521 -13.449 1.00 35.24 ? 295 GLN A CG 1 ATOM 471 C CD . GLN A 1 75 ? -11.041 -0.936 -11.983 1.00 42.60 ? 295 GLN A CD 1 ATOM 472 O OE1 . GLN A 1 75 ? -11.817 -0.395 -11.200 1.00 39.94 ? 295 GLN A OE1 1 ATOM 473 N NE2 . GLN A 1 75 ? -10.222 -1.917 -11.613 1.00 39.18 ? 295 GLN A NE2 1 ATOM 474 N N . TYR A 1 76 ? -14.266 -3.074 -15.797 1.00 40.06 ? 296 TYR A N 1 ATOM 475 C CA . TYR A 1 76 ? -15.573 -3.415 -16.407 1.00 46.41 ? 296 TYR A CA 1 ATOM 476 C C . TYR A 1 76 ? -16.378 -2.238 -16.974 1.00 45.30 ? 296 TYR A C 1 ATOM 477 O O . TYR A 1 76 ? -17.493 -2.417 -17.473 1.00 42.52 ? 296 TYR A O 1 ATOM 478 C CB . TYR A 1 76 ? -16.420 -4.310 -15.487 1.00 46.04 ? 296 TYR A CB 1 ATOM 479 C CG . TYR A 1 76 ? -15.716 -5.611 -15.176 1.00 52.87 ? 296 TYR A CG 1 ATOM 480 C CD1 . TYR A 1 76 ? -15.220 -5.875 -13.894 1.00 47.33 ? 296 TYR A CD1 1 ATOM 481 C CD2 . TYR A 1 76 ? -15.507 -6.563 -16.177 1.00 49.03 ? 296 TYR A CD2 1 ATOM 482 C CE1 . TYR A 1 76 ? -14.559 -7.058 -13.615 1.00 47.18 ? 296 TYR A CE1 1 ATOM 483 C CE2 . TYR A 1 76 ? -14.847 -7.750 -15.906 1.00 58.79 ? 296 TYR A CE2 1 ATOM 484 C CZ . TYR A 1 76 ? -14.375 -7.991 -14.626 1.00 59.66 ? 296 TYR A CZ 1 ATOM 485 O OH . TYR A 1 76 ? -13.718 -9.170 -14.361 1.00 77.36 ? 296 TYR A OH 1 ATOM 486 N N . ASN A 1 77 ? -15.792 -1.047 -16.913 1.00 43.28 ? 297 ASN A N 1 ATOM 487 C CA . ASN A 1 77 ? -16.361 0.126 -17.551 1.00 38.34 ? 297 ASN A CA 1 ATOM 488 C C . ASN A 1 77 ? -15.521 0.561 -18.749 1.00 36.38 ? 297 ASN A C 1 ATOM 489 O O . ASN A 1 77 ? -15.433 1.750 -19.035 1.00 34.40 ? 297 ASN A O 1 ATOM 490 C CB . ASN A 1 77 ? -16.488 1.272 -16.549 1.00 40.81 ? 297 ASN A CB 1 ATOM 491 C CG . ASN A 1 77 ? -15.149 1.721 -16.000 1.00 43.65 ? 297 ASN A CG 1 ATOM 492 O OD1 . ASN A 1 77 ? -14.083 1.331 -16.490 1.00 41.51 ? 297 ASN A OD1 1 ATOM 493 N ND2 . ASN A 1 77 ? -15.201 2.552 -14.978 1.00 45.34 ? 297 ASN A ND2 1 ATOM 494 N N . SER A 1 78 ? -14.883 -0.418 -19.395 1.00 33.95 ? 298 SER A N 1 ATOM 495 C CA . SER A 1 78 ? -14.053 -0.258 -20.603 1.00 45.31 ? 298 SER A CA 1 ATOM 496 C C . SER A 1 78 ? -12.542 -0.046 -20.345 1.00 47.01 ? 298 SER A C 1 ATOM 497 O O . SER A 1 78 ? -11.734 -0.106 -21.280 1.00 45.25 ? 298 SER A O 1 ATOM 498 C CB . SER A 1 78 ? -14.614 0.815 -21.553 1.00 40.19 ? 298 SER A CB 1 ATOM 499 O OG . SER A 1 78 ? -14.271 2.124 -21.117 1.00 39.00 ? 298 SER A OG 1 ATOM 500 N N . THR A 1 79 ? -12.174 0.194 -19.087 1.00 40.44 ? 299 THR A N 1 ATOM 501 C CA . THR A 1 79 ? -10.819 0.629 -18.744 1.00 42.80 ? 299 THR A CA 1 ATOM 502 C C . THR A 1 79 ? -10.107 -0.275 -17.750 1.00 43.49 ? 299 THR A C 1 ATOM 503 O O . THR A 1 79 ? -10.732 -1.062 -17.038 1.00 44.68 ? 299 THR A O 1 ATOM 504 C CB . THR A 1 79 ? -10.799 2.046 -18.130 1.00 44.77 ? 299 THR A CB 1 ATOM 505 O OG1 . THR A 1 79 ? -11.346 1.997 -16.809 1.00 44.21 ? 299 THR A OG1 1 ATOM 506 C CG2 . THR A 1 79 ? -11.580 3.041 -18.987 1.00 46.20 ? 299 THR A CG2 1 ATOM 507 N N . TYR A 1 80 ? -8.785 -0.136 -17.705 1.00 40.88 ? 300 TYR A N 1 ATOM 508 C CA . TYR A 1 80 ? -7.986 -0.781 -16.683 1.00 35.04 ? 300 TYR A CA 1 ATOM 509 C C . TYR A 1 80 ? -7.606 0.195 -15.579 1.00 31.59 ? 300 TYR A C 1 ATOM 510 O O . TYR A 1 80 ? -7.577 1.418 -15.773 1.00 29.83 ? 300 TYR A O 1 ATOM 511 C CB . TYR A 1 80 ? -6.699 -1.347 -17.272 1.00 33.31 ? 300 TYR A CB 1 ATOM 512 C CG . TYR A 1 80 ? -6.856 -2.559 -18.142 1.00 30.57 ? 300 TYR A CG 1 ATOM 513 C CD1 . TYR A 1 80 ? -6.638 -2.470 -19.512 1.00 35.11 ? 300 TYR A CD1 1 ATOM 514 C CD2 . TYR A 1 80 ? -7.200 -3.801 -17.602 1.00 32.24 ? 300 TYR A CD2 1 ATOM 515 C CE1 . TYR A 1 80 ? -6.766 -3.577 -20.331 1.00 30.59 ? 300 TYR A CE1 1 ATOM 516 C CE2 . TYR A 1 80 ? -7.319 -4.917 -18.412 1.00 34.47 ? 300 TYR A CE2 1 ATOM 517 C CZ . TYR A 1 80 ? -7.096 -4.793 -19.776 1.00 30.59 ? 300 TYR A CZ 1 ATOM 518 O OH . TYR A 1 80 ? -7.209 -5.878 -20.606 1.00 42.49 ? 300 TYR A OH 1 ATOM 519 N N . ARG A 1 81 ? -7.288 -0.372 -14.426 1.00 28.89 ? 301 ARG A N 1 ATOM 520 C CA . ARG A 1 81 ? -6.680 0.363 -13.333 1.00 28.74 ? 301 ARG A CA 1 ATOM 521 C C . ARG A 1 81 ? -5.272 -0.219 -13.076 1.00 28.16 ? 301 ARG A C 1 ATOM 522 O O . ARG A 1 81 ? -5.126 -1.424 -12.857 1.00 28.83 ? 301 ARG A O 1 ATOM 523 C CB . ARG A 1 81 ? -7.572 0.233 -12.123 1.00 24.89 ? 301 ARG A CB 1 ATOM 524 C CG . ARG A 1 81 ? -7.161 1.080 -10.952 1.00 28.62 ? 301 ARG A CG 1 ATOM 525 C CD . ARG A 1 81 ? -7.944 0.617 -9.759 1.00 27.08 ? 301 ARG A CD 1 ATOM 526 N NE . ARG A 1 81 ? -7.838 1.539 -8.641 1.00 25.73 ? 301 ARG A NE 1 ATOM 527 C CZ . ARG A 1 81 ? -7.252 1.232 -7.493 1.00 26.83 ? 301 ARG A CZ 1 ATOM 528 N NH1 . ARG A 1 81 ? -6.711 0.037 -7.332 1.00 28.55 ? 301 ARG A NH1 1 ATOM 529 N NH2 . ARG A 1 81 ? -7.207 2.121 -6.512 1.00 26.69 ? 301 ARG A NH2 1 ATOM 530 N N . VAL A 1 82 ? -4.248 0.635 -13.136 1.00 32.64 ? 302 VAL A N 1 ATOM 531 C CA . VAL A 1 82 ? -2.836 0.216 -13.010 1.00 29.04 ? 302 VAL A CA 1 ATOM 532 C C . VAL A 1 82 ? -2.189 0.897 -11.801 1.00 29.63 ? 302 VAL A C 1 ATOM 533 O O . VAL A 1 82 ? -2.237 2.122 -11.701 1.00 34.65 ? 302 VAL A O 1 ATOM 534 C CB . VAL A 1 82 ? -2.021 0.611 -14.253 1.00 28.02 ? 302 VAL A CB 1 ATOM 535 C CG1 . VAL A 1 82 ? -0.548 0.291 -14.054 1.00 30.00 ? 302 VAL A CG1 1 ATOM 536 C CG2 . VAL A 1 82 ? -2.553 -0.049 -15.525 1.00 28.18 ? 302 VAL A CG2 1 ATOM 537 N N . VAL A 1 83 ? -1.554 0.127 -10.912 1.00 28.05 ? 303 VAL A N 1 ATOM 538 C CA . VAL A 1 83 ? -1.027 0.686 -9.640 1.00 27.38 ? 303 VAL A CA 1 ATOM 539 C C . VAL A 1 83 ? 0.459 0.409 -9.327 1.00 25.23 ? 303 VAL A C 1 ATOM 540 O O . VAL A 1 83 ? 0.896 -0.743 -9.279 1.00 27.80 ? 303 VAL A O 1 ATOM 541 C CB . VAL A 1 83 ? -1.891 0.256 -8.431 1.00 22.06 ? 303 VAL A CB 1 ATOM 542 C CG1 . VAL A 1 83 ? -1.391 0.909 -7.147 1.00 28.00 ? 303 VAL A CG1 1 ATOM 543 C CG2 . VAL A 1 83 ? -3.352 0.631 -8.649 1.00 21.75 ? 303 VAL A CG2 1 ATOM 544 N N . SER A 1 84 ? 1.229 1.471 -9.093 1.00 23.44 ? 304 SER A N 1 ATOM 545 C CA . SER A 1 84 ? 2.609 1.324 -8.655 1.00 24.50 ? 304 SER A CA 1 ATOM 546 C C . SER A 1 84 ? 2.732 1.684 -7.169 1.00 25.77 ? 304 SER A C 1 ATOM 547 O O . SER A 1 84 ? 2.259 2.726 -6.742 1.00 25.33 ? 304 SER A O 1 ATOM 548 C CB . SER A 1 84 ? 3.530 2.210 -9.476 1.00 25.91 ? 304 SER A CB 1 ATOM 549 O OG . SER A 1 84 ? 4.886 2.022 -9.092 1.00 29.01 ? 304 SER A OG 1 ATOM 550 N N . VAL A 1 85 ? 3.370 0.821 -6.391 1.00 27.90 ? 305 VAL A N 1 ATOM 551 C CA . VAL A 1 85 ? 3.513 1.050 -4.942 1.00 26.72 ? 305 VAL A CA 1 ATOM 552 C C . VAL A 1 85 ? 4.981 1.291 -4.621 1.00 25.96 ? 305 VAL A C 1 ATOM 553 O O . VAL A 1 85 ? 5.822 0.476 -4.969 1.00 27.02 ? 305 VAL A O 1 ATOM 554 C CB . VAL A 1 85 ? 2.985 -0.160 -4.124 1.00 30.65 ? 305 VAL A CB 1 ATOM 555 C CG1 . VAL A 1 85 ? 3.196 0.051 -2.632 1.00 32.86 ? 305 VAL A CG1 1 ATOM 556 C CG2 . VAL A 1 85 ? 1.505 -0.410 -4.400 1.00 29.94 ? 305 VAL A CG2 1 ATOM 557 N N . LEU A 1 86 ? 5.288 2.410 -3.966 1.00 28.41 ? 306 LEU A N 1 ATOM 558 C CA . LEU A 1 86 ? 6.647 2.678 -3.497 1.00 28.35 ? 306 LEU A CA 1 ATOM 559 C C . LEU A 1 86 ? 6.761 2.635 -1.964 1.00 29.66 ? 306 LEU A C 1 ATOM 560 O O . LEU A 1 86 ? 6.151 3.457 -1.276 1.00 25.04 ? 306 LEU A O 1 ATOM 561 C CB . LEU A 1 86 ? 7.144 4.030 -4.008 1.00 22.96 ? 306 LEU A CB 1 ATOM 562 C CG . LEU A 1 86 ? 8.527 4.507 -3.513 1.00 22.66 ? 306 LEU A CG 1 ATOM 563 C CD1 . LEU A 1 86 ? 9.668 3.700 -4.103 1.00 23.39 ? 306 LEU A CD1 1 ATOM 564 C CD2 . LEU A 1 86 ? 8.727 5.987 -3.818 1.00 20.79 ? 306 LEU A CD2 1 ATOM 565 N N . THR A 1 87 ? 7.553 1.696 -1.444 1.00 32.46 ? 307 THR A N 1 ATOM 566 C CA . THR A 1 87 ? 7.856 1.655 -0.001 1.00 37.22 ? 307 THR A CA 1 ATOM 567 C C . THR A 1 87 ? 8.677 2.884 0.357 1.00 34.08 ? 307 THR A C 1 ATOM 568 O O . THR A 1 87 ? 9.554 3.291 -0.406 1.00 32.92 ? 307 THR A O 1 ATOM 569 C CB . THR A 1 87 ? 8.659 0.401 0.395 1.00 34.95 ? 307 THR A CB 1 ATOM 570 O OG1 . THR A 1 87 ? 7.999 -0.763 -0.099 1.00 38.54 ? 307 THR A OG1 1 ATOM 571 C CG2 . THR A 1 87 ? 8.778 0.289 1.915 1.00 35.18 ? 307 THR A CG2 1 ATOM 572 N N . VAL A 1 88 ? 8.380 3.480 1.505 1.00 33.20 ? 308 VAL A N 1 ATOM 573 C CA . VAL A 1 88 ? 9.135 4.631 1.972 1.00 35.45 ? 308 VAL A CA 1 ATOM 574 C C . VAL A 1 88 ? 9.636 4.400 3.394 1.00 43.70 ? 308 VAL A C 1 ATOM 575 O O . VAL A 1 88 ? 9.092 3.575 4.147 1.00 38.51 ? 308 VAL A O 1 ATOM 576 C CB . VAL A 1 88 ? 8.325 5.956 1.891 1.00 35.38 ? 308 VAL A CB 1 ATOM 577 C CG1 . VAL A 1 88 ? 7.702 6.116 0.511 1.00 33.31 ? 308 VAL A CG1 1 ATOM 578 C CG2 . VAL A 1 88 ? 7.248 6.021 2.970 1.00 28.89 ? 308 VAL A CG2 1 ATOM 579 N N . LEU A 1 89 ? 10.680 5.133 3.751 1.00 33.15 ? 309 LEU A N 1 ATOM 580 C CA . LEU A 1 89 ? 11.258 5.016 5.060 1.00 35.32 ? 309 LEU A CA 1 ATOM 581 C C . LEU A 1 89 ? 10.470 5.923 5.980 1.00 29.62 ? 309 LEU A C 1 ATOM 582 O O . LEU A 1 89 ? 10.097 7.030 5.606 1.00 31.93 ? 309 LEU A O 1 ATOM 583 C CB . LEU A 1 89 ? 12.748 5.384 5.028 1.00 39.05 ? 309 LEU A CB 1 ATOM 584 C CG . LEU A 1 89 ? 13.603 4.489 4.114 1.00 40.61 ? 309 LEU A CG 1 ATOM 585 C CD1 . LEU A 1 89 ? 14.938 5.136 3.766 1.00 41.73 ? 309 LEU A CD1 1 ATOM 586 C CD2 . LEU A 1 89 ? 13.805 3.102 4.719 1.00 38.55 ? 309 LEU A CD2 1 ATOM 587 N N . HIS A 1 90 ? 10.194 5.428 7.176 1.00 28.91 ? 310 HIS A N 1 ATOM 588 C CA . HIS A 1 90 ? 9.444 6.181 8.166 1.00 26.58 ? 310 HIS A CA 1 ATOM 589 C C . HIS A 1 90 ? 9.992 7.565 8.300 1.00 29.04 ? 310 HIS A C 1 ATOM 590 O O . HIS A 1 90 ? 9.255 8.537 8.140 1.00 38.20 ? 310 HIS A O 1 ATOM 591 C CB . HIS A 1 90 ? 9.470 5.464 9.510 1.00 22.82 ? 310 HIS A CB 1 ATOM 592 C CG . HIS A 1 90 ? 8.856 4.098 9.477 1.00 22.38 ? 310 HIS A CG 1 ATOM 593 N ND1 . HIS A 1 90 ? 9.504 3.023 8.982 1.00 28.16 ? 310 HIS A ND1 1 ATOM 594 C CD2 . HIS A 1 90 ? 7.602 3.647 9.892 1.00 26.44 ? 310 HIS A CD2 1 ATOM 595 C CE1 . HIS A 1 90 ? 8.709 1.935 9.074 1.00 27.66 ? 310 HIS A CE1 1 ATOM 596 N NE2 . HIS A 1 90 ? 7.546 2.314 9.637 1.00 27.02 ? 310 HIS A NE2 1 ATOM 597 N N . GLN A 1 91 ? 11.292 7.671 8.577 1.00 35.56 ? 311 GLN A N 1 ATOM 598 C CA . GLN A 1 91 ? 11.907 8.974 8.845 1.00 38.86 ? 311 GLN A CA 1 ATOM 599 C C . GLN A 1 91 ? 11.972 9.862 7.624 1.00 33.29 ? 311 GLN A C 1 ATOM 600 O O . GLN A 1 91 ? 11.765 11.068 7.740 1.00 33.47 ? 311 GLN A O 1 ATOM 601 C CB . GLN A 1 91 ? 13.289 8.849 9.488 1.00 45.19 ? 311 GLN A CB 1 ATOM 602 C CG . GLN A 1 91 ? 13.255 8.884 11.009 1.00 51.53 ? 311 GLN A CG 1 ATOM 603 C CD . GLN A 1 91 ? 12.576 10.121 11.590 1.00 57.34 ? 311 GLN A CD 1 ATOM 604 O OE1 . GLN A 1 91 ? 12.447 11.157 10.932 1.00 64.69 ? 311 GLN A OE1 1 ATOM 605 N NE2 . GLN A 1 91 ? 12.142 10.014 12.839 1.00 55.99 ? 311 GLN A NE2 1 ATOM 606 N N . ASP A 1 92 ? 12.233 9.263 6.460 1.00 34.00 ? 312 ASP A N 1 ATOM 607 C CA . ASP A 1 92 ? 12.178 9.986 5.188 1.00 31.26 ? 312 ASP A CA 1 ATOM 608 C C . ASP A 1 92 ? 10.874 10.755 5.100 1.00 32.45 ? 312 ASP A C 1 ATOM 609 O O . ASP A 1 92 ? 10.876 11.978 4.886 1.00 40.39 ? 312 ASP A O 1 ATOM 610 C CB . ASP A 1 92 ? 12.332 9.031 3.991 1.00 39.99 ? 312 ASP A CB 1 ATOM 611 C CG . ASP A 1 92 ? 13.794 8.719 3.660 1.00 45.74 ? 312 ASP A CG 1 ATOM 612 O OD1 . ASP A 1 92 ? 14.682 9.023 4.485 1.00 41.01 ? 312 ASP A OD1 1 ATOM 613 O OD2 . ASP A 1 92 ? 14.056 8.169 2.563 1.00 46.40 ? 312 ASP A OD2 1 ATOM 614 N N . TRP A 1 93 ? 9.760 10.054 5.319 1.00 32.01 ? 313 TRP A N 1 ATOM 615 C CA . TRP A 1 93 ? 8.445 10.681 5.247 1.00 26.47 ? 313 TRP A CA 1 ATOM 616 C C . TRP A 1 93 ? 8.260 11.731 6.293 1.00 29.87 ? 313 TRP A C 1 ATOM 617 O O . TRP A 1 93 ? 7.804 12.840 5.987 1.00 32.18 ? 313 TRP A O 1 ATOM 618 C CB . TRP A 1 93 ? 7.336 9.645 5.364 1.00 31.41 ? 313 TRP A CB 1 ATOM 619 C CG . TRP A 1 93 ? 5.976 10.265 5.229 1.00 29.47 ? 313 TRP A CG 1 ATOM 620 C CD1 . TRP A 1 93 ? 5.127 10.680 6.253 1.00 27.49 ? 313 TRP A CD1 1 ATOM 621 C CD2 . TRP A 1 93 ? 5.269 10.604 3.981 1.00 31.18 ? 313 TRP A CD2 1 ATOM 622 N NE1 . TRP A 1 93 ? 3.974 11.218 5.739 1.00 29.92 ? 313 TRP A NE1 1 ATOM 623 C CE2 . TRP A 1 93 ? 3.994 11.203 4.384 1.00 35.58 ? 313 TRP A CE2 1 ATOM 624 C CE3 . TRP A 1 93 ? 5.556 10.476 2.626 1.00 35.39 ? 313 TRP A CE3 1 ATOM 625 C CZ2 . TRP A 1 93 ? 3.059 11.644 3.451 1.00 34.02 ? 313 TRP A CZ2 1 ATOM 626 C CZ3 . TRP A 1 93 ? 4.602 10.919 1.696 1.00 36.27 ? 313 TRP A CZ3 1 ATOM 627 C CH2 . TRP A 1 93 ? 3.385 11.487 2.104 1.00 36.21 ? 313 TRP A CH2 1 ATOM 628 N N . LEU A 1 94 ? 8.583 11.394 7.543 1.00 28.96 ? 314 LEU A N 1 ATOM 629 C CA . LEU A 1 94 ? 8.381 12.329 8.652 1.00 32.57 ? 314 LEU A CA 1 ATOM 630 C C . LEU A 1 94 ? 9.261 13.586 8.537 1.00 33.20 ? 314 LEU A C 1 ATOM 631 O O . LEU A 1 94 ? 8.843 14.674 8.934 1.00 34.37 ? 314 LEU A O 1 ATOM 632 C CB . LEU A 1 94 ? 8.559 11.617 10.004 1.00 33.47 ? 314 LEU A CB 1 ATOM 633 C CG . LEU A 1 94 ? 7.523 10.508 10.246 1.00 40.20 ? 314 LEU A CG 1 ATOM 634 C CD1 . LEU A 1 94 ? 7.826 9.733 11.515 1.00 35.69 ? 314 LEU A CD1 1 ATOM 635 C CD2 . LEU A 1 94 ? 6.103 11.063 10.276 1.00 42.26 ? 314 LEU A CD2 1 ATOM 636 N N . ASN A 1 95 ? 10.465 13.435 7.977 1.00 35.12 ? 315 ASN A N 1 ATOM 637 C CA . ASN A 1 95 ? 11.328 14.581 7.673 1.00 36.26 ? 315 ASN A CA 1 ATOM 638 C C . ASN A 1 95 ? 10.823 15.427 6.512 1.00 42.75 ? 315 ASN A C 1 ATOM 639 O O . ASN A 1 95 ? 11.351 16.513 6.249 1.00 47.55 ? 315 ASN A O 1 ATOM 640 C CB . ASN A 1 95 ? 12.759 14.131 7.381 1.00 36.31 ? 315 ASN A CB 1 ATOM 641 C CG . ASN A 1 95 ? 13.471 13.625 8.609 1.00 38.48 ? 315 ASN A CG 1 ATOM 642 O OD1 . ASN A 1 95 ? 13.166 14.021 9.741 1.00 38.60 ? 315 ASN A OD1 1 ATOM 643 N ND2 . ASN A 1 95 ? 14.433 12.740 8.397 1.00 39.55 ? 315 ASN A ND2 1 ATOM 644 N N . GLY A 1 96 ? 9.827 14.915 5.796 1.00 36.70 ? 316 GLY A N 1 ATOM 645 C CA . GLY A 1 96 ? 9.123 15.722 4.813 1.00 36.47 ? 316 GLY A CA 1 ATOM 646 C C . GLY A 1 96 ? 9.632 15.630 3.391 1.00 35.96 ? 316 GLY A C 1 ATOM 647 O O . GLY A 1 96 ? 9.387 16.528 2.597 1.00 38.27 ? 316 GLY A O 1 ATOM 648 N N . LYS A 1 97 ? 10.321 14.545 3.056 1.00 35.92 ? 317 LYS A N 1 ATOM 649 C CA . LYS A 1 97 ? 10.750 14.323 1.671 1.00 42.78 ? 317 LYS A CA 1 ATOM 650 C C . LYS A 1 97 ? 9.565 14.326 0.699 1.00 42.50 ? 317 LYS A C 1 ATOM 651 O O . LYS A 1 97 ? 8.439 14.011 1.083 1.00 40.63 ? 317 LYS A O 1 ATOM 652 C CB . LYS A 1 97 ? 11.555 13.027 1.551 1.00 47.22 ? 317 LYS A CB 1 ATOM 653 C CG . LYS A 1 97 ? 12.825 13.040 2.393 1.00 51.75 ? 317 LYS A CG 1 ATOM 654 C CD . LYS A 1 97 ? 13.862 12.031 1.920 1.00 49.90 ? 317 LYS A CD 1 ATOM 655 C CE . LYS A 1 97 ? 15.096 12.058 2.816 1.00 44.23 ? 317 LYS A CE 1 ATOM 656 N NZ . LYS A 1 97 ? 15.708 13.415 2.924 1.00 39.49 ? 317 LYS A NZ 1 ATOM 657 N N . GLU A 1 98 ? 9.829 14.697 -0.550 1.00 46.66 ? 318 GLU A N 1 ATOM 658 C CA . GLU A 1 98 ? 8.791 14.819 -1.570 1.00 39.31 ? 318 GLU A CA 1 ATOM 659 C C . GLU A 1 98 ? 8.883 13.677 -2.552 1.00 36.10 ? 318 GLU A C 1 ATOM 660 O O . GLU A 1 98 ? 9.947 13.420 -3.110 1.00 39.49 ? 318 GLU A O 1 ATOM 661 C CB . GLU A 1 98 ? 8.907 16.155 -2.312 1.00 35.99 ? 318 GLU A CB 1 ATOM 662 C CG . GLU A 1 98 ? 8.340 17.328 -1.534 1.00 44.33 ? 318 GLU A CG 1 ATOM 663 C CD . GLU A 1 98 ? 8.316 18.618 -2.328 1.00 52.44 ? 318 GLU A CD 1 ATOM 664 O OE1 . GLU A 1 98 ? 7.837 18.616 -3.484 1.00 55.12 ? 318 GLU A OE1 1 ATOM 665 O OE2 . GLU A 1 98 ? 8.770 19.643 -1.784 1.00 55.49 ? 318 GLU A OE2 1 ATOM 666 N N . TYR A 1 99 ? 7.753 13.004 -2.761 1.00 34.19 ? 319 TYR A N 1 ATOM 667 C CA . TYR A 1 99 ? 7.699 11.798 -3.578 1.00 33.41 ? 319 TYR A CA 1 ATOM 668 C C . TYR A 1 99 ? 6.944 12.031 -4.890 1.00 33.34 ? 319 TYR A C 1 ATOM 669 O O . TYR A 1 99 ? 5.753 12.346 -4.895 1.00 37.58 ? 319 TYR A O 1 ATOM 670 C CB . TYR A 1 99 ? 7.080 10.646 -2.791 1.00 27.55 ? 319 TYR A CB 1 ATOM 671 C CG . TYR A 1 99 ? 7.892 10.256 -1.587 1.00 27.85 ? 319 TYR A CG 1 ATOM 672 C CD1 . TYR A 1 99 ? 7.726 10.920 -0.382 1.00 25.11 ? 319 TYR A CD1 1 ATOM 673 C CD2 . TYR A 1 99 ? 8.821 9.221 -1.651 1.00 27.33 ? 319 TYR A CD2 1 ATOM 674 C CE1 . TYR A 1 99 ? 8.472 10.575 0.730 1.00 29.65 ? 319 TYR A CE1 1 ATOM 675 C CE2 . TYR A 1 99 ? 9.572 8.864 -0.542 1.00 32.19 ? 319 TYR A CE2 1 ATOM 676 C CZ . TYR A 1 99 ? 9.387 9.547 0.644 1.00 29.32 ? 319 TYR A CZ 1 ATOM 677 O OH . TYR A 1 99 ? 10.107 9.213 1.755 1.00 37.50 ? 319 TYR A OH 1 ATOM 678 N N . LYS A 1 100 ? 7.653 11.877 -5.995 1.00 30.56 ? 320 LYS A N 1 ATOM 679 C CA . LYS A 1 100 ? 7.097 12.207 -7.295 1.00 32.44 ? 320 LYS A CA 1 ATOM 680 C C . LYS A 1 100 ? 6.848 10.960 -8.107 1.00 31.54 ? 320 LYS A C 1 ATOM 681 O O . LYS A 1 100 ? 7.747 10.147 -8.292 1.00 30.56 ? 320 LYS A O 1 ATOM 682 C CB . LYS A 1 100 ? 8.023 13.154 -8.057 1.00 31.24 ? 320 LYS A CB 1 ATOM 683 C CG . LYS A 1 100 ? 7.511 13.502 -9.447 1.00 39.60 ? 320 LYS A CG 1 ATOM 684 C CD . LYS A 1 100 ? 8.591 14.121 -10.317 1.00 45.78 ? 320 LYS A CD 1 ATOM 685 C CE . LYS A 1 100 ? 8.764 15.607 -10.051 1.00 43.68 ? 320 LYS A CE 1 ATOM 686 N NZ . LYS A 1 100 ? 9.614 16.196 -11.122 1.00 46.65 ? 320 LYS A NZ 1 ATOM 687 N N . CYS A 1 101 ? 5.616 10.810 -8.581 1.00 34.93 ? 321 CYS A N 1 ATOM 688 C CA . CYS A 1 101 ? 5.276 9.748 -9.521 1.00 31.78 ? 321 CYS A CA 1 ATOM 689 C C . CYS A 1 101 ? 5.031 10.342 -10.906 1.00 36.33 ? 321 CYS A C 1 ATOM 690 O O . CYS A 1 101 ? 4.245 11.287 -11.043 1.00 41.31 ? 321 CYS A O 1 ATOM 691 C CB . CYS A 1 101 ? 4.026 8.989 -9.063 1.00 33.30 ? 321 CYS A CB 1 ATOM 692 S SG . CYS A 1 101 ? 3.561 7.677 -10.217 1.00 36.20 ? 321 CYS A SG 1 ATOM 693 N N . LYS A 1 102 ? 5.690 9.772 -11.917 1.00 35.04 ? 322 LYS A N 1 ATOM 694 C CA . LYS A 1 102 ? 5.597 10.223 -13.305 1.00 36.88 ? 322 LYS A CA 1 ATOM 695 C C . LYS A 1 102 ? 5.095 9.082 -14.185 1.00 36.07 ? 322 LYS A C 1 ATOM 696 O O . LYS A 1 102 ? 5.696 8.000 -14.227 1.00 35.71 ? 322 LYS A O 1 ATOM 697 C CB . LYS A 1 102 ? 6.961 10.699 -13.821 1.00 41.43 ? 322 LYS A CB 1 ATOM 698 C CG . LYS A 1 102 ? 6.920 11.271 -15.234 1.00 45.47 ? 322 LYS A CG 1 ATOM 699 C CD . LYS A 1 102 ? 8.291 11.287 -15.893 1.00 40.15 ? 322 LYS A CD 1 ATOM 700 C CE . LYS A 1 102 ? 8.295 12.232 -17.079 1.00 53.00 ? 322 LYS A CE 1 ATOM 701 N NZ . LYS A 1 102 ? 9.520 12.100 -17.915 1.00 65.13 ? 322 LYS A NZ 1 ATOM 702 N N . VAL A 1 103 ? 4.005 9.339 -14.900 1.00 31.74 ? 323 VAL A N 1 ATOM 703 C CA . VAL A 1 103 ? 3.295 8.294 -15.618 1.00 28.88 ? 323 VAL A CA 1 ATOM 704 C C . VAL A 1 103 ? 3.317 8.555 -17.128 1.00 31.67 ? 323 VAL A C 1 ATOM 705 O O . VAL A 1 103 ? 2.972 9.644 -17.585 1.00 30.04 ? 323 VAL A O 1 ATOM 706 C CB . VAL A 1 103 ? 1.848 8.171 -15.097 1.00 32.61 ? 323 VAL A CB 1 ATOM 707 C CG1 . VAL A 1 103 ? 1.018 7.254 -15.984 1.00 35.73 ? 323 VAL A CG1 1 ATOM 708 C CG2 . VAL A 1 103 ? 1.832 7.696 -13.642 1.00 33.57 ? 323 VAL A CG2 1 ATOM 709 N N . SER A 1 104 ? 3.732 7.546 -17.890 1.00 34.07 ? 324 SER A N 1 ATOM 710 C CA . SER A 1 104 ? 3.792 7.626 -19.350 1.00 37.41 ? 324 SER A CA 1 ATOM 711 C C . SER A 1 104 ? 2.976 6.501 -19.965 1.00 37.93 ? 324 SER A C 1 ATOM 712 O O . SER A 1 104 ? 3.051 5.350 -19.518 1.00 39.89 ? 324 SER A O 1 ATOM 713 C CB . SER A 1 104 ? 5.243 7.545 -19.852 1.00 37.26 ? 324 SER A CB 1 ATOM 714 O OG . SER A 1 104 ? 6.066 8.507 -19.217 1.00 45.92 ? 324 SER A OG 1 ATOM 715 N N . ASN A 1 105 ? 2.219 6.846 -21.006 1.00 35.74 ? 325 ASN A N 1 ATOM 716 C CA . ASN A 1 105 ? 1.286 5.937 -21.672 1.00 33.58 ? 325 ASN A CA 1 ATOM 717 C C . ASN A 1 105 ? 1.001 6.490 -23.066 1.00 37.39 ? 325 ASN A C 1 ATOM 718 O O . ASN A 1 105 ? 0.925 7.706 -23.248 1.00 40.05 ? 325 ASN A O 1 ATOM 719 C CB . ASN A 1 105 ? 0.001 5.811 -20.827 1.00 40.99 ? 325 ASN A CB 1 ATOM 720 C CG . ASN A 1 105 ? -1.103 5.023 -21.518 1.00 41.45 ? 325 ASN A CG 1 ATOM 721 O OD1 . ASN A 1 105 ? -1.852 5.572 -22.310 1.00 48.13 ? 325 ASN A OD1 1 ATOM 722 N ND2 . ASN A 1 105 ? -1.226 3.738 -21.191 1.00 40.13 ? 325 ASN A ND2 1 ATOM 723 N N . LYS A 1 106 ? 0.851 5.607 -24.051 1.00 37.64 ? 326 LYS A N 1 ATOM 724 C CA . LYS A 1 106 ? 0.623 6.024 -25.453 1.00 38.38 ? 326 LYS A CA 1 ATOM 725 C C . LYS A 1 106 ? -0.573 6.962 -25.678 1.00 44.70 ? 326 LYS A C 1 ATOM 726 O O . LYS A 1 106 ? -0.538 7.800 -26.582 1.00 46.24 ? 326 LYS A O 1 ATOM 727 C CB . LYS A 1 106 ? 0.514 4.806 -26.372 1.00 30.25 ? 326 LYS A CB 1 ATOM 728 C CG . LYS A 1 106 ? 1.820 4.061 -26.540 1.00 30.51 ? 326 LYS A CG 1 ATOM 729 N N . ALA A 1 107 ? -1.615 6.820 -24.859 1.00 43.32 ? 327 ALA A N 1 ATOM 730 C CA . ALA A 1 107 ? -2.805 7.677 -24.946 1.00 42.64 ? 327 ALA A CA 1 ATOM 731 C C . ALA A 1 107 ? -2.631 9.032 -24.241 1.00 44.91 ? 327 ALA A C 1 ATOM 732 O O . ALA A 1 107 ? -3.584 9.799 -24.099 1.00 46.01 ? 327 ALA A O 1 ATOM 733 C CB . ALA A 1 107 ? -4.034 6.939 -24.413 1.00 36.51 ? 327 ALA A CB 1 ATOM 734 N N . LEU A 1 108 ? -1.409 9.326 -23.815 1.00 48.47 ? 328 LEU A N 1 ATOM 735 C CA . LEU A 1 108 ? -1.104 10.558 -23.107 1.00 42.96 ? 328 LEU A CA 1 ATOM 736 C C . LEU A 1 108 ? -0.149 11.362 -23.978 1.00 47.22 ? 328 LEU A C 1 ATOM 737 O O . LEU A 1 108 ? 0.916 10.855 -24.331 1.00 55.13 ? 328 LEU A O 1 ATOM 738 C CB . LEU A 1 108 ? -0.424 10.213 -21.783 1.00 44.45 ? 328 LEU A CB 1 ATOM 739 C CG . LEU A 1 108 ? -0.816 10.801 -20.431 1.00 48.74 ? 328 LEU A CG 1 ATOM 740 C CD1 . LEU A 1 108 ? -2.304 10.657 -20.156 1.00 45.38 ? 328 LEU A CD1 1 ATOM 741 C CD2 . LEU A 1 108 ? -0.016 10.074 -19.360 1.00 47.80 ? 328 LEU A CD2 1 ATOM 742 N N . PRO A 1 109 ? -0.519 12.607 -24.344 1.00 48.99 ? 329 PRO A N 1 ATOM 743 C CA . PRO A 1 109 ? 0.393 13.438 -25.147 1.00 50.18 ? 329 PRO A CA 1 ATOM 744 C C . PRO A 1 109 ? 1.674 13.759 -24.380 1.00 52.74 ? 329 PRO A C 1 ATOM 745 O O . PRO A 1 109 ? 2.765 13.664 -24.942 1.00 48.43 ? 329 PRO A O 1 ATOM 746 C CB . PRO A 1 109 ? -0.416 14.716 -25.400 1.00 54.01 ? 329 PRO A CB 1 ATOM 747 C CG . PRO A 1 109 ? -1.840 14.332 -25.159 1.00 57.54 ? 329 PRO A CG 1 ATOM 748 C CD . PRO A 1 109 ? -1.792 13.298 -24.075 1.00 50.43 ? 329 PRO A CD 1 ATOM 749 N N . ALA A 1 110 ? 1.535 14.111 -23.102 1.00 48.04 ? 330 ALA A N 1 ATOM 750 C CA . ALA A 1 110 ? 2.682 14.344 -22.234 1.00 48.75 ? 330 ALA A CA 1 ATOM 751 C C . ALA A 1 110 ? 2.552 13.519 -20.956 1.00 48.55 ? 330 ALA A C 1 ATOM 752 O O . ALA A 1 110 ? 1.449 13.355 -20.442 1.00 46.23 ? 330 ALA A O 1 ATOM 753 C CB . ALA A 1 110 ? 2.806 15.824 -21.903 1.00 52.13 ? 330 ALA A CB 1 ATOM 754 N N . PRO A 1 111 ? 3.679 12.989 -20.443 1.00 47.17 ? 331 PRO A N 1 ATOM 755 C CA . PRO A 1 111 ? 3.640 12.272 -19.169 1.00 44.66 ? 331 PRO A CA 1 ATOM 756 C C . PRO A 1 111 ? 3.025 13.107 -18.042 1.00 41.36 ? 331 PRO A C 1 ATOM 757 O O . PRO A 1 111 ? 3.249 14.315 -17.971 1.00 44.86 ? 331 PRO A O 1 ATOM 758 C CB . PRO A 1 111 ? 5.114 11.989 -18.877 1.00 43.37 ? 331 PRO A CB 1 ATOM 759 C CG . PRO A 1 111 ? 5.763 11.948 -20.214 1.00 48.58 ? 331 PRO A CG 1 ATOM 760 C CD . PRO A 1 111 ? 5.007 12.913 -21.083 1.00 48.18 ? 331 PRO A CD 1 ATOM 761 N N . ILE A 1 112 ? 2.238 12.461 -17.189 1.00 34.88 ? 332 ILE A N 1 ATOM 762 C CA . ILE A 1 112 ? 1.625 13.131 -16.047 1.00 40.47 ? 332 ILE A CA 1 ATOM 763 C C . ILE A 1 112 ? 2.481 12.970 -14.798 1.00 36.91 ? 332 ILE A C 1 ATOM 764 O O . ILE A 1 112 ? 2.971 11.879 -14.496 1.00 41.36 ? 332 ILE A O 1 ATOM 765 C CB . ILE A 1 112 ? 0.189 12.616 -15.780 1.00 42.92 ? 332 ILE A CB 1 ATOM 766 C CG1 . ILE A 1 112 ? -0.716 12.936 -16.983 1.00 35.44 ? 332 ILE A CG1 1 ATOM 767 C CG2 . ILE A 1 112 ? -0.365 13.208 -14.486 1.00 31.31 ? 332 ILE A CG2 1 ATOM 768 C CD1 . ILE A 1 112 ? -2.118 12.363 -16.903 1.00 35.24 ? 332 ILE A CD1 1 ATOM 769 N N . GLU A 1 113 ? 2.652 14.067 -14.073 1.00 39.94 ? 333 GLU A N 1 ATOM 770 C CA . GLU A 1 113 ? 3.454 14.067 -12.862 1.00 39.49 ? 333 GLU A CA 1 ATOM 771 C C . GLU A 1 113 ? 2.616 14.469 -11.672 1.00 34.62 ? 333 GLU A C 1 ATOM 772 O O . GLU A 1 113 ? 1.817 15.395 -11.751 1.00 42.19 ? 333 GLU A O 1 ATOM 773 C CB . GLU A 1 113 ? 4.657 15.005 -12.999 1.00 38.57 ? 333 GLU A CB 1 ATOM 774 C CG . GLU A 1 113 ? 5.599 14.618 -14.131 1.00 42.90 ? 333 GLU A CG 1 ATOM 775 C CD . GLU A 1 113 ? 6.960 15.296 -14.052 1.00 52.06 ? 333 GLU A CD 1 ATOM 776 O OE1 . GLU A 1 113 ? 7.671 15.312 -15.076 1.00 58.56 ? 333 GLU A OE1 1 ATOM 777 O OE2 . GLU A 1 113 ? 7.332 15.804 -12.973 1.00 63.50 ? 333 GLU A OE2 1 ATOM 778 N N . LYS A 1 114 ? 2.807 13.763 -10.569 1.00 31.86 ? 334 LYS A N 1 ATOM 779 C CA . LYS A 1 114 ? 2.174 14.114 -9.322 1.00 30.32 ? 334 LYS A CA 1 ATOM 780 C C . LYS A 1 114 ? 3.195 14.023 -8.206 1.00 34.03 ? 334 LYS A C 1 ATOM 781 O O . LYS A 1 114 ? 4.099 13.195 -8.263 1.00 38.10 ? 334 LYS A O 1 ATOM 782 C CB . LYS A 1 114 ? 1.009 13.164 -9.021 1.00 36.06 ? 334 LYS A CB 1 ATOM 783 C CG . LYS A 1 114 ? -0.161 13.229 -9.994 1.00 39.17 ? 334 LYS A CG 1 ATOM 784 C CD . LYS A 1 114 ? -0.931 14.536 -9.874 1.00 40.77 ? 334 LYS A CD 1 ATOM 785 C CE . LYS A 1 114 ? -2.222 14.469 -10.672 1.00 41.77 ? 334 LYS A CE 1 ATOM 786 N NZ . LYS A 1 114 ? -3.007 15.730 -10.571 1.00 41.44 ? 334 LYS A NZ 1 ATOM 787 N N . THR A 1 115 ? 3.026 14.857 -7.183 1.00 29.57 ? 335 THR A N 1 ATOM 788 C CA . THR A 1 115 ? 3.951 14.923 -6.064 1.00 34.34 ? 335 THR A CA 1 ATOM 789 C C . THR A 1 115 ? 3.170 15.095 -4.768 1.00 31.23 ? 335 THR A C 1 ATOM 790 O O . THR A 1 115 ? 2.362 16.008 -4.656 1.00 38.93 ? 335 THR A O 1 ATOM 791 C CB . THR A 1 115 ? 4.918 16.121 -6.228 1.00 32.65 ? 335 THR A CB 1 ATOM 792 O OG1 . THR A 1 115 ? 5.745 15.906 -7.370 1.00 33.93 ? 335 THR A OG1 1 ATOM 793 C CG2 . THR A 1 115 ? 5.816 16.312 -4.988 1.00 32.65 ? 335 THR A CG2 1 ATOM 794 N N . ILE A 1 116 ? 3.408 14.210 -3.805 1.00 36.32 ? 336 ILE A N 1 ATOM 795 C CA . ILE A 1 116 ? 2.924 14.402 -2.433 1.00 38.28 ? 336 ILE A CA 1 ATOM 796 C C . ILE A 1 116 ? 4.053 14.328 -1.425 1.00 37.92 ? 336 ILE A C 1 ATOM 797 O O . ILE A 1 116 ? 5.148 13.839 -1.719 1.00 44.27 ? 336 ILE A O 1 ATOM 798 C CB . ILE A 1 116 ? 1.830 13.390 -1.977 1.00 43.17 ? 336 ILE A CB 1 ATOM 799 C CG1 . ILE A 1 116 ? 2.085 11.973 -2.513 1.00 41.20 ? 336 ILE A CG1 1 ATOM 800 C CG2 . ILE A 1 116 ? 0.434 13.902 -2.318 1.00 48.69 ? 336 ILE A CG2 1 ATOM 801 C CD1 . ILE A 1 116 ? 3.083 11.156 -1.730 1.00 33.05 ? 336 ILE A CD1 1 ATOM 802 N N . SER A 1 117 ? 3.746 14.799 -0.226 1.00 38.99 ? 337 SER A N 1 ATOM 803 C CA . SER A 1 117 ? 4.621 14.719 0.930 1.00 33.81 ? 337 SER A CA 1 ATOM 804 C C . SER A 1 117 ? 3.776 15.073 2.125 1.00 33.68 ? 337 SER A C 1 ATOM 805 O O . SER A 1 117 ? 2.602 15.413 1.984 1.00 40.37 ? 337 SER A O 1 ATOM 806 C CB . SER A 1 117 ? 5.783 15.716 0.807 1.00 35.42 ? 337 SER A CB 1 ATOM 807 O OG . SER A 1 117 ? 5.320 17.050 0.681 1.00 31.51 ? 337 SER A OG 1 ATOM 808 N N . LYS A 1 118 ? 4.373 14.995 3.306 1.00 39.20 ? 338 LYS A N 1 ATOM 809 C CA . LYS A 1 118 ? 3.741 15.467 4.516 1.00 33.59 ? 338 LYS A CA 1 ATOM 810 C C . LYS A 1 118 ? 3.510 16.969 4.363 1.00 35.91 ? 338 LYS A C 1 ATOM 811 O O . LYS A 1 118 ? 4.314 17.653 3.727 1.00 41.65 ? 338 LYS A O 1 ATOM 812 C CB . LYS A 1 118 ? 4.696 15.214 5.675 1.00 40.23 ? 338 LYS A CB 1 ATOM 813 C CG . LYS A 1 118 ? 4.080 15.374 7.047 1.00 46.86 ? 338 LYS A CG 1 ATOM 814 C CD . LYS A 1 118 ? 5.115 15.132 8.127 1.00 45.42 ? 338 LYS A CD 1 ATOM 815 C CE . LYS A 1 118 ? 6.002 16.347 8.318 1.00 47.81 ? 338 LYS A CE 1 ATOM 816 N NZ . LYS A 1 118 ? 6.882 16.175 9.500 1.00 44.38 ? 338 LYS A NZ 1 ATOM 817 N N . ALA A 1 119 ? 2.421 17.483 4.931 1.00 36.63 ? 339 ALA A N 1 ATOM 818 C CA . ALA A 1 119 ? 2.224 18.924 5.007 1.00 37.98 ? 339 ALA A CA 1 ATOM 819 C C . ALA A 1 119 ? 3.461 19.537 5.650 1.00 45.99 ? 339 ALA A C 1 ATOM 820 O O . ALA A 1 119 ? 4.067 18.930 6.537 1.00 46.04 ? 339 ALA A O 1 ATOM 821 C CB . ALA A 1 119 ? 0.985 19.259 5.815 1.00 40.61 ? 339 ALA A CB 1 ATOM 822 N N . LYS A 1 120 ? 3.843 20.725 5.190 1.00 40.80 ? 340 LYS A N 1 ATOM 823 C CA . LYS A 1 120 ? 5.061 21.369 5.660 1.00 37.41 ? 340 LYS A CA 1 ATOM 824 C C . LYS A 1 120 ? 4.768 22.191 6.901 1.00 33.35 ? 340 LYS A C 1 ATOM 825 O O . LYS A 1 120 ? 3.651 22.670 7.087 1.00 33.87 ? 340 LYS A O 1 ATOM 826 C CB . LYS A 1 120 ? 5.678 22.237 4.555 1.00 41.55 ? 340 LYS A CB 1 ATOM 827 C CG . LYS A 1 120 ? 6.049 21.460 3.299 1.00 50.28 ? 340 LYS A CG 1 ATOM 828 C CD . LYS A 1 120 ? 6.401 22.370 2.129 1.00 56.18 ? 340 LYS A CD 1 ATOM 829 C CE . LYS A 1 120 ? 7.906 22.478 1.929 1.00 66.53 ? 340 LYS A CE 1 ATOM 830 N NZ . LYS A 1 120 ? 8.505 21.223 1.388 1.00 67.46 ? 340 LYS A NZ 1 ATOM 831 N N . GLY A 1 121 ? 5.764 22.332 7.764 1.00 33.26 ? 341 GLY A N 1 ATOM 832 C CA . GLY A 1 121 ? 5.608 23.123 8.971 1.00 27.91 ? 341 GLY A CA 1 ATOM 833 C C . GLY A 1 121 ? 6.123 22.429 10.210 1.00 32.11 ? 341 GLY A C 1 ATOM 834 O O . GLY A 1 121 ? 6.222 21.198 10.261 1.00 35.88 ? 341 GLY A O 1 ATOM 835 N N . GLN A 1 122 ? 6.440 23.232 11.219 1.00 33.63 ? 342 GLN A N 1 ATOM 836 C CA . GLN A 1 122 ? 7.012 22.734 12.461 1.00 40.82 ? 342 GLN A CA 1 ATOM 837 C C . GLN A 1 122 ? 6.013 21.865 13.241 1.00 42.17 ? 342 GLN A C 1 ATOM 838 O O . GLN A 1 122 ? 5.015 22.371 13.747 1.00 50.60 ? 342 GLN A O 1 ATOM 839 C CB . GLN A 1 122 ? 7.485 23.910 13.312 1.00 42.38 ? 342 GLN A CB 1 ATOM 840 C CG . GLN A 1 122 ? 8.308 23.518 14.522 1.00 60.67 ? 342 GLN A CG 1 ATOM 841 C CD . GLN A 1 122 ? 8.867 24.724 15.247 1.00 74.82 ? 342 GLN A CD 1 ATOM 842 O OE1 . GLN A 1 122 ? 9.148 25.760 14.636 1.00 71.86 ? 342 GLN A OE1 1 ATOM 843 N NE2 . GLN A 1 122 ? 9.032 24.596 16.560 1.00 73.52 ? 342 GLN A NE2 1 ATOM 844 N N . PRO A 1 123 ? 6.294 20.557 13.358 1.00 39.25 ? 343 PRO A N 1 ATOM 845 C CA . PRO A 1 123 ? 5.378 19.652 14.058 1.00 38.08 ? 343 PRO A CA 1 ATOM 846 C C . PRO A 1 123 ? 5.162 20.081 15.520 1.00 38.33 ? 343 PRO A C 1 ATOM 847 O O . PRO A 1 123 ? 6.116 20.477 16.185 1.00 38.19 ? 343 PRO A O 1 ATOM 848 C CB . PRO A 1 123 ? 6.104 18.293 14.004 1.00 39.02 ? 343 PRO A CB 1 ATOM 849 C CG . PRO A 1 123 ? 7.214 18.450 13.016 1.00 39.79 ? 343 PRO A CG 1 ATOM 850 C CD . PRO A 1 123 ? 7.581 19.906 13.046 1.00 37.33 ? 343 PRO A CD 1 ATOM 851 N N . ARG A 1 124 ? 3.920 20.004 15.997 1.00 33.34 ? 344 ARG A N 1 ATOM 852 C CA . ARG A 1 124 ? 3.563 20.384 17.372 1.00 38.45 ? 344 ARG A CA 1 ATOM 853 C C . ARG A 1 124 ? 2.870 19.233 18.098 1.00 37.47 ? 344 ARG A C 1 ATOM 854 O O . ARG A 1 124 ? 2.043 18.521 17.511 1.00 31.78 ? 344 ARG A O 1 ATOM 855 C CB . ARG A 1 124 ? 2.636 21.602 17.385 1.00 39.29 ? 344 ARG A CB 1 ATOM 856 C CG . ARG A 1 124 ? 3.313 22.921 17.061 1.00 43.75 ? 344 ARG A CG 1 ATOM 857 C CD . ARG A 1 124 ? 2.331 24.084 17.146 1.00 49.01 ? 344 ARG A CD 1 ATOM 858 N NE . ARG A 1 124 ? 1.632 24.152 18.429 1.00 44.95 ? 344 ARG A NE 1 ATOM 859 C CZ . ARG A 1 124 ? 0.651 25.006 18.703 1.00 43.79 ? 344 ARG A CZ 1 ATOM 860 N NH1 . ARG A 1 124 ? 0.253 25.885 17.790 1.00 45.51 ? 344 ARG A NH1 1 ATOM 861 N NH2 . ARG A 1 124 ? 0.076 24.992 19.897 1.00 43.26 ? 344 ARG A NH2 1 ATOM 862 N N . GLU A 1 125 ? 3.200 19.086 19.380 1.00 35.66 ? 345 GLU A N 1 ATOM 863 C CA . GLU A 1 125 ? 2.732 17.969 20.195 1.00 44.47 ? 345 GLU A CA 1 ATOM 864 C C . GLU A 1 125 ? 1.270 18.086 20.630 1.00 40.08 ? 345 GLU A C 1 ATOM 865 O O . GLU A 1 125 ? 0.878 19.093 21.212 1.00 38.12 ? 345 GLU A O 1 ATOM 866 C CB . GLU A 1 125 ? 3.615 17.806 21.434 1.00 46.77 ? 345 GLU A CB 1 ATOM 867 C CG . GLU A 1 125 ? 3.416 16.468 22.134 1.00 47.62 ? 345 GLU A CG 1 ATOM 868 C CD . GLU A 1 125 ? 4.048 16.411 23.508 1.00 49.41 ? 345 GLU A CD 1 ATOM 869 O OE1 . GLU A 1 125 ? 3.993 17.423 24.235 1.00 51.76 ? 345 GLU A OE1 1 ATOM 870 O OE2 . GLU A 1 125 ? 4.588 15.344 23.864 1.00 55.56 ? 345 GLU A OE2 1 ATOM 871 N N . PRO A 1 126 ? 0.466 17.040 20.374 1.00 39.51 ? 346 PRO A N 1 ATOM 872 C CA . PRO A 1 126 ? -0.926 17.089 20.817 1.00 44.87 ? 346 PRO A CA 1 ATOM 873 C C . PRO A 1 126 ? -1.068 16.893 22.326 1.00 43.98 ? 346 PRO A C 1 ATOM 874 O O . PRO A 1 126 ? -0.357 16.086 22.921 1.00 39.23 ? 346 PRO A O 1 ATOM 875 C CB . PRO A 1 126 ? -1.575 15.929 20.068 1.00 42.44 ? 346 PRO A CB 1 ATOM 876 C CG . PRO A 1 126 ? -0.474 14.968 19.820 1.00 40.88 ? 346 PRO A CG 1 ATOM 877 C CD . PRO A 1 126 ? 0.776 15.791 19.654 1.00 40.42 ? 346 PRO A CD 1 ATOM 878 N N . GLN A 1 127 ? -1.961 17.660 22.934 1.00 44.78 ? 347 GLN A N 1 ATOM 879 C CA . GLN A 1 127 ? -2.328 17.441 24.321 1.00 47.60 ? 347 GLN A CA 1 ATOM 880 C C . GLN A 1 127 ? -3.609 16.625 24.324 1.00 45.29 ? 347 GLN A C 1 ATOM 881 O O . GLN A 1 127 ? -4.558 16.937 23.598 1.00 42.43 ? 347 GLN A O 1 ATOM 882 C CB . GLN A 1 127 ? -2.494 18.769 25.056 1.00 56.31 ? 347 GLN A CB 1 ATOM 883 C CG . GLN A 1 127 ? -1.170 19.482 25.301 1.00 69.15 ? 347 GLN A CG 1 ATOM 884 C CD . GLN A 1 127 ? -1.300 20.995 25.318 1.00 95.98 ? 347 GLN A CD 1 ATOM 885 O OE1 . GLN A 1 127 ? -0.403 21.707 24.863 1.00 92.73 ? 347 GLN A OE1 1 ATOM 886 N NE2 . GLN A 1 127 ? -2.417 21.495 25.843 1.00 110.13 ? 347 GLN A NE2 1 ATOM 887 N N . VAL A 1 128 ? -3.612 15.559 25.119 1.00 44.14 ? 348 VAL A N 1 ATOM 888 C CA . VAL A 1 128 ? -4.702 14.595 25.129 1.00 38.46 ? 348 VAL A CA 1 ATOM 889 C C . VAL A 1 128 ? -5.386 14.590 26.490 1.00 44.51 ? 348 VAL A C 1 ATOM 890 O O . VAL A 1 128 ? -4.729 14.505 27.533 1.00 49.10 ? 348 VAL A O 1 ATOM 891 C CB . VAL A 1 128 ? -4.197 13.182 24.759 1.00 39.04 ? 348 VAL A CB 1 ATOM 892 C CG1 . VAL A 1 128 ? -5.351 12.190 24.650 1.00 32.20 ? 348 VAL A CG1 1 ATOM 893 C CG2 . VAL A 1 128 ? -3.425 13.235 23.448 1.00 35.14 ? 348 VAL A CG2 1 ATOM 894 N N . TYR A 1 129 ? -6.709 14.711 26.466 1.00 40.16 ? 349 TYR A N 1 ATOM 895 C CA . TYR A 1 129 ? -7.504 14.742 27.679 1.00 41.84 ? 349 TYR A CA 1 ATOM 896 C C . TYR A 1 129 ? -8.691 13.814 27.506 1.00 41.76 ? 349 TYR A C 1 ATOM 897 O O . TYR A 1 129 ? -9.303 13.785 26.435 1.00 37.38 ? 349 TYR A O 1 ATOM 898 C CB . TYR A 1 129 ? -8.008 16.162 27.958 1.00 39.29 ? 349 TYR A CB 1 ATOM 899 C CG . TYR A 1 129 ? -6.945 17.237 27.914 1.00 45.01 ? 349 TYR A CG 1 ATOM 900 C CD1 . TYR A 1 129 ? -5.898 17.263 28.847 1.00 53.56 ? 349 TYR A CD1 1 ATOM 901 C CD2 . TYR A 1 129 ? -6.992 18.241 26.953 1.00 43.36 ? 349 TYR A CD2 1 ATOM 902 C CE1 . TYR A 1 129 ? -4.925 18.254 28.807 1.00 52.21 ? 349 TYR A CE1 1 ATOM 903 C CE2 . TYR A 1 129 ? -6.027 19.236 26.904 1.00 48.61 ? 349 TYR A CE2 1 ATOM 904 C CZ . TYR A 1 129 ? -4.997 19.241 27.830 1.00 51.51 ? 349 TYR A CZ 1 ATOM 905 O OH . TYR A 1 129 ? -4.046 20.238 27.772 1.00 54.58 ? 349 TYR A OH 1 ATOM 906 N N . THR A 1 130 ? -9.015 13.063 28.554 1.00 41.64 ? 350 THR A N 1 ATOM 907 C CA . THR A 1 130 ? -10.229 12.250 28.559 1.00 40.69 ? 350 THR A CA 1 ATOM 908 C C . THR A 1 130 ? -11.276 12.889 29.431 1.00 41.04 ? 350 THR A C 1 ATOM 909 O O . THR A 1 130 ? -10.971 13.398 30.514 1.00 47.95 ? 350 THR A O 1 ATOM 910 C CB . THR A 1 130 ? -10.005 10.829 29.084 1.00 39.69 ? 350 THR A CB 1 ATOM 911 O OG1 . THR A 1 130 ? -9.324 10.891 30.341 1.00 32.22 ? 350 THR A OG1 1 ATOM 912 C CG2 . THR A 1 130 ? -9.202 10.018 28.094 1.00 33.99 ? 350 THR A CG2 1 ATOM 913 N N . LEU A 1 131 ? -12.517 12.840 28.961 1.00 35.71 ? 351 LEU A N 1 ATOM 914 C CA . LEU A 1 131 ? -13.631 13.457 29.668 1.00 36.06 ? 351 LEU A CA 1 ATOM 915 C C . LEU A 1 131 ? -14.703 12.415 29.914 1.00 35.00 ? 351 LEU A C 1 ATOM 916 O O . LEU A 1 131 ? -15.104 11.715 28.979 1.00 27.64 ? 351 LEU A O 1 ATOM 917 C CB . LEU A 1 131 ? -14.190 14.641 28.881 1.00 32.14 ? 351 LEU A CB 1 ATOM 918 C CG . LEU A 1 131 ? -13.174 15.698 28.431 1.00 37.33 ? 351 LEU A CG 1 ATOM 919 C CD1 . LEU A 1 131 ? -13.846 16.737 27.548 1.00 39.96 ? 351 LEU A CD1 1 ATOM 920 C CD2 . LEU A 1 131 ? -12.492 16.361 29.619 1.00 33.43 ? 351 LEU A CD2 1 ATOM 921 N N . PRO A 1 132 ? -15.134 12.275 31.184 1.00 29.44 ? 352 PRO A N 1 ATOM 922 C CA . PRO A 1 132 ? -16.198 11.340 31.508 1.00 34.63 ? 352 PRO A CA 1 ATOM 923 C C . PRO A 1 132 ? -17.538 11.863 30.984 1.00 30.61 ? 352 PRO A C 1 ATOM 924 O O . PRO A 1 132 ? -17.637 13.043 30.654 1.00 30.89 ? 352 PRO A O 1 ATOM 925 C CB . PRO A 1 132 ? -16.170 11.282 33.051 1.00 35.57 ? 352 PRO A CB 1 ATOM 926 C CG . PRO A 1 132 ? -15.558 12.569 33.480 1.00 31.52 ? 352 PRO A CG 1 ATOM 927 C CD . PRO A 1 132 ? -14.603 12.960 32.383 1.00 34.77 ? 352 PRO A CD 1 ATOM 928 N N . PRO A 1 133 ? -18.546 10.973 30.862 1.00 30.65 ? 353 PRO A N 1 ATOM 929 C CA . PRO A 1 133 ? -19.909 11.332 30.479 1.00 28.52 ? 353 PRO A CA 1 ATOM 930 C C . PRO A 1 133 ? -20.508 12.391 31.383 1.00 32.43 ? 353 PRO A C 1 ATOM 931 O O . PRO A 1 133 ? -20.248 12.384 32.584 1.00 39.56 ? 353 PRO A O 1 ATOM 932 C CB . PRO A 1 133 ? -20.698 10.029 30.666 1.00 27.22 ? 353 PRO A CB 1 ATOM 933 C CG . PRO A 1 133 ? -19.765 9.031 31.241 1.00 26.06 ? 353 PRO A CG 1 ATOM 934 C CD . PRO A 1 133 ? -18.380 9.515 30.972 1.00 27.77 ? 353 PRO A CD 1 ATOM 935 N N . SER A 1 134 ? -21.288 13.298 30.799 1.00 28.65 ? 354 SER A N 1 ATOM 936 C CA . SER A 1 134 ? -22.145 14.199 31.561 1.00 36.73 ? 354 SER A CA 1 ATOM 937 C C . SER A 1 134 ? -23.061 13.384 32.474 1.00 36.93 ? 354 SER A C 1 ATOM 938 O O . SER A 1 134 ? -23.445 12.261 32.136 1.00 33.95 ? 354 SER A O 1 ATOM 939 C CB . SER A 1 134 ? -22.983 15.043 30.600 1.00 35.48 ? 354 SER A CB 1 ATOM 940 O OG . SER A 1 134 ? -23.887 15.895 31.277 1.00 39.41 ? 354 SER A OG 1 ATOM 941 N N . ARG A 1 135 ? -23.394 13.945 33.635 1.00 42.25 ? 355 ARG A N 1 ATOM 942 C CA . ARG A 1 135 ? -24.341 13.310 34.549 1.00 38.90 ? 355 ARG A CA 1 ATOM 943 C C . ARG A 1 135 ? -25.714 13.210 33.887 1.00 39.68 ? 355 ARG A C 1 ATOM 944 O O . ARG A 1 135 ? -26.478 12.295 34.177 1.00 36.52 ? 355 ARG A O 1 ATOM 945 C CB . ARG A 1 135 ? -24.431 14.074 35.879 1.00 36.69 ? 355 ARG A CB 1 ATOM 946 N N . GLU A 1 136 ? -26.007 14.139 32.974 1.00 42.64 ? 356 GLU A N 1 ATOM 947 C CA . GLU A 1 136 ? -27.298 14.170 32.280 1.00 41.84 ? 356 GLU A CA 1 ATOM 948 C C . GLU A 1 136 ? -27.464 12.997 31.320 1.00 37.23 ? 356 GLU A C 1 ATOM 949 O O . GLU A 1 136 ? -28.578 12.700 30.892 1.00 39.92 ? 356 GLU A O 1 ATOM 950 C CB . GLU A 1 136 ? -27.504 15.493 31.524 1.00 48.25 ? 356 GLU A CB 1 ATOM 951 C CG . GLU A 1 136 ? -27.425 16.759 32.372 1.00 55.96 ? 356 GLU A CG 1 ATOM 952 C CD . GLU A 1 136 ? -28.449 16.800 33.491 1.00 74.15 ? 356 GLU A CD 1 ATOM 953 O OE1 . GLU A 1 136 ? -28.039 16.993 34.658 1.00 75.51 ? 356 GLU A OE1 1 ATOM 954 O OE2 . GLU A 1 136 ? -29.658 16.634 33.212 1.00 94.16 ? 356 GLU A OE2 1 ATOM 955 N N . GLU A 1 137 ? -26.362 12.331 30.990 1.00 37.66 ? 357 GLU A N 1 ATOM 956 C CA . GLU A 1 137 ? -26.400 11.194 30.073 1.00 37.83 ? 357 GLU A CA 1 ATOM 957 C C . GLU A 1 137 ? -26.475 9.877 30.842 1.00 34.97 ? 357 GLU A C 1 ATOM 958 O O . GLU A 1 137 ? -26.631 8.815 30.248 1.00 29.79 ? 357 GLU A O 1 ATOM 959 C CB . GLU A 1 137 ? -25.176 11.210 29.153 1.00 38.21 ? 357 GLU A CB 1 ATOM 960 C CG . GLU A 1 137 ? -25.170 10.111 28.097 1.00 32.68 ? 357 GLU A CG 1 ATOM 961 C CD . GLU A 1 137 ? -23.949 10.156 27.195 1.00 36.80 ? 357 GLU A CD 1 ATOM 962 O OE1 . GLU A 1 137 ? -22.841 10.449 27.695 1.00 39.29 ? 357 GLU A OE1 1 ATOM 963 O OE2 . GLU A 1 137 ? -24.094 9.886 25.978 1.00 34.18 ? 357 GLU A OE2 1 ATOM 964 N N . MET A 1 138 ? -26.373 9.953 32.169 1.00 29.27 ? 358 MET A N 1 ATOM 965 C CA . MET A 1 138 ? -26.384 8.762 33.020 1.00 25.68 ? 358 MET A CA 1 ATOM 966 C C . MET A 1 138 ? -27.785 8.175 33.116 1.00 28.84 ? 358 MET A C 1 ATOM 967 O O . MET A 1 138 ? -28.018 7.175 33.775 1.00 31.98 ? 358 MET A O 1 ATOM 968 C CB . MET A 1 138 ? -25.827 9.109 34.407 1.00 34.50 ? 358 MET A CB 1 ATOM 969 C CG . MET A 1 138 ? -24.341 9.475 34.400 1.00 31.58 ? 358 MET A CG 1 ATOM 970 S SD . MET A 1 138 ? -23.245 8.285 33.577 1.00 34.17 ? 358 MET A SD 1 ATOM 971 C CE . MET A 1 138 ? -23.612 6.768 34.452 1.00 24.85 ? 358 MET A CE 1 ATOM 972 N N . THR A 1 139 ? -28.711 8.809 32.414 1.00 37.99 ? 359 THR A N 1 ATOM 973 C CA . THR A 1 139 ? -30.064 8.313 32.250 1.00 42.44 ? 359 THR A CA 1 ATOM 974 C C . THR A 1 139 ? -30.181 7.308 31.098 1.00 37.56 ? 359 THR A C 1 ATOM 975 O O . THR A 1 139 ? -31.101 6.482 31.075 1.00 37.84 ? 359 THR A O 1 ATOM 976 C CB . THR A 1 139 ? -31.032 9.507 32.098 1.00 44.67 ? 359 THR A CB 1 ATOM 977 O OG1 . THR A 1 139 ? -31.684 9.724 33.355 1.00 46.20 ? 359 THR A OG1 1 ATOM 978 C CG2 . THR A 1 139 ? -32.076 9.283 30.992 1.00 51.13 ? 359 THR A CG2 1 ATOM 979 N N . LYS A 1 140 ? -29.230 7.349 30.170 1.00 34.96 ? 360 LYS A N 1 ATOM 980 C CA . LYS A 1 140 ? -29.339 6.559 28.929 1.00 30.68 ? 360 LYS A CA 1 ATOM 981 C C . LYS A 1 140 ? -28.854 5.106 29.078 1.00 27.92 ? 360 LYS A C 1 ATOM 982 O O . LYS A 1 140 ? -28.290 4.741 30.104 1.00 33.56 ? 360 LYS A O 1 ATOM 983 C CB . LYS A 1 140 ? -28.617 7.285 27.796 1.00 29.65 ? 360 LYS A CB 1 ATOM 984 C CG . LYS A 1 140 ? -28.987 8.760 27.672 1.00 26.79 ? 360 LYS A CG 1 ATOM 985 N N . ASN A 1 141 ? -29.091 4.268 28.070 1.00 28.33 ? 361 ASN A N 1 ATOM 986 C CA . ASN A 1 141 ? -28.576 2.890 28.078 1.00 28.82 ? 361 ASN A CA 1 ATOM 987 C C . ASN A 1 141 ? -27.082 2.822 27.805 1.00 29.45 ? 361 ASN A C 1 ATOM 988 O O . ASN A 1 141 ? -26.388 1.911 28.264 1.00 31.54 ? 361 ASN A O 1 ATOM 989 C CB . ASN A 1 141 ? -29.301 2.025 27.045 1.00 34.08 ? 361 ASN A CB 1 ATOM 990 C CG . ASN A 1 141 ? -30.788 1.967 27.280 1.00 39.11 ? 361 ASN A CG 1 ATOM 991 O OD1 . ASN A 1 141 ? -31.266 2.196 28.393 1.00 49.62 ? 361 ASN A OD1 1 ATOM 992 N ND2 . ASN A 1 141 ? -31.535 1.667 26.227 1.00 39.80 ? 361 ASN A ND2 1 ATOM 993 N N . GLN A 1 142 ? -26.594 3.773 27.015 1.00 28.40 ? 362 GLN A N 1 ATOM 994 C CA . GLN A 1 142 ? -25.184 3.815 26.670 1.00 22.62 ? 362 GLN A CA 1 ATOM 995 C C . GLN A 1 142 ? -24.672 5.196 26.981 1.00 22.07 ? 362 GLN A C 1 ATOM 996 O O . GLN A 1 142 ? -25.457 6.144 27.111 1.00 23.62 ? 362 GLN A O 1 ATOM 997 C CB . GLN A 1 142 ? -24.975 3.420 25.193 1.00 23.04 ? 362 GLN A CB 1 ATOM 998 C CG . GLN A 1 142 ? -25.150 1.926 24.957 1.00 23.44 ? 362 GLN A CG 1 ATOM 999 C CD . GLN A 1 142 ? -25.251 1.510 23.482 1.00 31.75 ? 362 GLN A CD 1 ATOM 1000 O OE1 . GLN A 1 142 ? -25.150 2.322 22.557 1.00 27.09 ? 362 GLN A OE1 1 ATOM 1001 N NE2 . GLN A 1 142 ? -25.467 0.224 23.271 1.00 28.59 ? 362 GLN A NE2 1 ATOM 1002 N N . VAL A 1 143 ? -23.358 5.329 27.125 1.00 24.17 ? 363 VAL A N 1 ATOM 1003 C CA . VAL A 1 143 ? -22.803 6.610 27.547 1.00 22.51 ? 363 VAL A CA 1 ATOM 1004 C C . VAL A 1 143 ? -21.540 6.903 26.768 1.00 20.73 ? 363 VAL A C 1 ATOM 1005 O O . VAL A 1 143 ? -20.860 5.986 26.329 1.00 23.94 ? 363 VAL A O 1 ATOM 1006 C CB . VAL A 1 143 ? -22.483 6.625 29.070 1.00 22.89 ? 363 VAL A CB 1 ATOM 1007 C CG1 . VAL A 1 143 ? -23.684 6.149 29.873 1.00 27.83 ? 363 VAL A CG1 1 ATOM 1008 C CG2 . VAL A 1 143 ? -21.280 5.747 29.384 1.00 18.92 ? 363 VAL A CG2 1 ATOM 1009 N N . SER A 1 144 ? -21.216 8.184 26.648 1.00 23.68 ? 364 SER A N 1 ATOM 1010 C CA . SER A 1 144 ? -20.102 8.635 25.844 1.00 25.77 ? 364 SER A CA 1 ATOM 1011 C C . SER A 1 144 ? -18.870 8.967 26.665 1.00 29.53 ? 364 SER A C 1 ATOM 1012 O O . SER A 1 144 ? -18.945 9.669 27.685 1.00 35.51 ? 364 SER A O 1 ATOM 1013 C CB . SER A 1 144 ? -20.519 9.861 25.028 1.00 28.15 ? 364 SER A CB 1 ATOM 1014 O OG . SER A 1 144 ? -21.771 9.647 24.408 1.00 27.09 ? 364 SER A OG 1 ATOM 1015 N N . LEU A 1 145 ? -17.735 8.449 26.215 1.00 26.43 ? 365 LEU A N 1 ATOM 1016 C CA . LEU A 1 145 ? -16.440 8.786 26.793 1.00 23.25 ? 365 LEU A CA 1 ATOM 1017 C C . LEU A 1 145 ? -15.736 9.637 25.758 1.00 31.40 ? 365 LEU A C 1 ATOM 1018 O O . LEU A 1 145 ? -15.689 9.285 24.552 1.00 21.03 ? 365 LEU A O 1 ATOM 1019 C CB . LEU A 1 145 ? -15.651 7.524 27.118 1.00 27.22 ? 365 LEU A CB 1 ATOM 1020 C CG . LEU A 1 145 ? -16.401 6.462 27.946 1.00 27.75 ? 365 LEU A CG 1 ATOM 1021 C CD1 . LEU A 1 145 ? -15.494 5.302 28.278 1.00 26.81 ? 365 LEU A CD1 1 ATOM 1022 C CD2 . LEU A 1 145 ? -16.931 7.058 29.229 1.00 35.83 ? 365 LEU A CD2 1 ATOM 1023 N N . THR A 1 146 ? -15.253 10.792 26.198 1.00 25.83 ? 366 THR A N 1 ATOM 1024 C CA . THR A 1 146 ? -14.674 11.727 25.250 1.00 30.49 ? 366 THR A CA 1 ATOM 1025 C C . THR A 1 146 ? -13.149 11.752 25.368 1.00 32.97 ? 366 THR A C 1 ATOM 1026 O O . THR A 1 146 ? -12.600 11.841 26.473 1.00 26.16 ? 366 THR A O 1 ATOM 1027 C CB . THR A 1 146 ? -15.287 13.138 25.399 1.00 27.55 ? 366 THR A CB 1 ATOM 1028 O OG1 . THR A 1 146 ? -16.669 13.117 24.985 1.00 25.24 ? 366 THR A OG1 1 ATOM 1029 C CG2 . THR A 1 146 ? -14.522 14.150 24.557 1.00 26.46 ? 366 THR A CG2 1 ATOM 1030 N N . CYS A 1 147 ? -12.480 11.657 24.221 1.00 24.17 ? 367 CYS A N 1 ATOM 1031 C CA . CYS A 1 147 ? -11.045 11.887 24.129 1.00 26.28 ? 367 CYS A CA 1 ATOM 1032 C C . CYS A 1 147 ? -10.807 13.123 23.266 1.00 30.82 ? 367 CYS A C 1 ATOM 1033 O O . CYS A 1 147 ? -11.023 13.111 22.042 1.00 25.49 ? 367 CYS A O 1 ATOM 1034 C CB . CYS A 1 147 ? -10.331 10.657 23.542 1.00 30.15 ? 367 CYS A CB 1 ATOM 1035 S SG . CYS A 1 147 ? -8.518 10.735 23.443 1.00 36.58 ? 367 CYS A SG 1 ATOM 1036 N N . VAL A 1 148 ? -10.405 14.202 23.925 1.00 32.00 ? 368 VAL A N 1 ATOM 1037 C CA . VAL A 1 148 ? -10.049 15.452 23.261 1.00 33.90 ? 368 VAL A CA 1 ATOM 1038 C C . VAL A 1 148 ? -8.571 15.412 22.887 1.00 36.83 ? 368 VAL A C 1 ATOM 1039 O O . VAL A 1 148 ? -7.727 15.122 23.737 1.00 38.02 ? 368 VAL A O 1 ATOM 1040 C CB . VAL A 1 148 ? -10.325 16.658 24.192 1.00 37.92 ? 368 VAL A CB 1 ATOM 1041 C CG1 . VAL A 1 148 ? -9.668 17.939 23.682 1.00 39.80 ? 368 VAL A CG1 1 ATOM 1042 C CG2 . VAL A 1 148 ? -11.823 16.865 24.353 1.00 38.11 ? 368 VAL A CG2 1 ATOM 1043 N N . VAL A 1 149 ? -8.265 15.680 21.617 1.00 34.43 ? 369 VAL A N 1 ATOM 1044 C CA . VAL A 1 149 ? -6.879 15.806 21.162 1.00 34.20 ? 369 VAL A CA 1 ATOM 1045 C C . VAL A 1 149 ? -6.692 17.166 20.500 1.00 34.96 ? 369 VAL A C 1 ATOM 1046 O O . VAL A 1 149 ? -7.176 17.372 19.388 1.00 40.66 ? 369 VAL A O 1 ATOM 1047 C CB . VAL A 1 149 ? -6.490 14.707 20.142 1.00 30.73 ? 369 VAL A CB 1 ATOM 1048 C CG1 . VAL A 1 149 ? -4.987 14.713 19.907 1.00 31.57 ? 369 VAL A CG1 1 ATOM 1049 C CG2 . VAL A 1 149 ? -6.931 13.322 20.598 1.00 27.77 ? 369 VAL A CG2 1 ATOM 1050 N N . LYS A 1 150 ? -5.995 18.087 21.168 1.00 34.13 ? 370 LYS A N 1 ATOM 1051 C CA . LYS A 1 150 ? -5.787 19.446 20.615 1.00 35.56 ? 370 LYS A CA 1 ATOM 1052 C C . LYS A 1 150 ? -4.332 19.922 20.563 1.00 37.68 ? 370 LYS A C 1 ATOM 1053 O O . LYS A 1 150 ? -3.488 19.489 21.355 1.00 42.71 ? 370 LYS A O 1 ATOM 1054 C CB . LYS A 1 150 ? -6.654 20.489 21.326 1.00 35.76 ? 370 LYS A CB 1 ATOM 1055 C CG . LYS A 1 150 ? -6.172 20.939 22.704 1.00 41.33 ? 370 LYS A CG 1 ATOM 1056 C CD . LYS A 1 150 ? -7.007 22.111 23.214 1.00 34.77 ? 370 LYS A CD 1 ATOM 1057 N N . GLY A 1 151 ? -4.061 20.823 19.621 1.00 31.39 ? 371 GLY A N 1 ATOM 1058 C CA . GLY A 1 151 ? -2.752 21.464 19.496 1.00 31.09 ? 371 GLY A CA 1 ATOM 1059 C C . GLY A 1 151 ? -1.718 20.638 18.752 1.00 33.94 ? 371 GLY A C 1 ATOM 1060 O O . GLY A 1 151 ? -0.528 20.735 19.045 1.00 41.46 ? 371 GLY A O 1 ATOM 1061 N N . PHE A 1 152 ? -2.174 19.828 17.794 1.00 29.27 ? 372 PHE A N 1 ATOM 1062 C CA . PHE A 1 152 ? -1.268 19.021 16.994 1.00 32.62 ? 372 PHE A CA 1 ATOM 1063 C C . PHE A 1 152 ? -1.041 19.587 15.602 1.00 31.01 ? 372 PHE A C 1 ATOM 1064 O O . PHE A 1 152 ? -1.957 20.092 14.958 1.00 25.13 ? 372 PHE A O 1 ATOM 1065 C CB . PHE A 1 152 ? -1.648 17.520 16.942 1.00 26.24 ? 372 PHE A CB 1 ATOM 1066 C CG . PHE A 1 152 ? -2.991 17.213 16.310 1.00 28.85 ? 372 PHE A CG 1 ATOM 1067 C CD1 . PHE A 1 152 ? -4.161 17.244 17.064 1.00 29.36 ? 372 PHE A CD1 1 ATOM 1068 C CD2 . PHE A 1 152 ? -3.075 16.798 14.985 1.00 26.55 ? 372 PHE A CD2 1 ATOM 1069 C CE1 . PHE A 1 152 ? -5.386 16.927 16.498 1.00 33.17 ? 372 PHE A CE1 1 ATOM 1070 C CE2 . PHE A 1 152 ? -4.297 16.481 14.413 1.00 27.54 ? 372 PHE A CE2 1 ATOM 1071 C CZ . PHE A 1 152 ? -5.455 16.540 15.168 1.00 31.52 ? 372 PHE A CZ 1 ATOM 1072 N N . TYR A 1 153 ? 0.214 19.515 15.180 1.00 34.90 ? 373 TYR A N 1 ATOM 1073 C CA . TYR A 1 153 ? 0.582 19.764 13.813 1.00 41.52 ? 373 TYR A CA 1 ATOM 1074 C C . TYR A 1 153 ? 1.698 18.802 13.447 1.00 36.46 ? 373 TYR A C 1 ATOM 1075 O O . TYR A 1 153 ? 2.602 18.577 14.261 1.00 30.15 ? 373 TYR A O 1 ATOM 1076 C CB . TYR A 1 153 ? 1.034 21.213 13.594 1.00 40.78 ? 373 TYR A CB 1 ATOM 1077 C CG . TYR A 1 153 ? 1.088 21.519 12.118 1.00 41.31 ? 373 TYR A CG 1 ATOM 1078 C CD1 . TYR A 1 153 ? 2.264 21.345 11.390 1.00 35.73 ? 373 TYR A CD1 1 ATOM 1079 C CD2 . TYR A 1 153 ? -0.058 21.928 11.439 1.00 37.24 ? 373 TYR A CD2 1 ATOM 1080 C CE1 . TYR A 1 153 ? 2.292 21.585 10.029 1.00 43.51 ? 373 TYR A CE1 1 ATOM 1081 C CE2 . TYR A 1 153 ? -0.037 22.177 10.087 1.00 44.64 ? 373 TYR A CE2 1 ATOM 1082 C CZ . TYR A 1 153 ? 1.136 21.999 9.385 1.00 42.33 ? 373 TYR A CZ 1 ATOM 1083 O OH . TYR A 1 153 ? 1.137 22.250 8.041 1.00 38.05 ? 373 TYR A OH 1 ATOM 1084 N N . PRO A 1 154 ? 1.642 18.221 12.229 1.00 32.01 ? 374 PRO A N 1 ATOM 1085 C CA . PRO A 1 154 ? 0.581 18.323 11.216 1.00 37.70 ? 374 PRO A CA 1 ATOM 1086 C C . PRO A 1 154 ? -0.652 17.456 11.534 1.00 36.36 ? 374 PRO A C 1 ATOM 1087 O O . PRO A 1 154 ? -0.675 16.774 12.554 1.00 36.47 ? 374 PRO A O 1 ATOM 1088 C CB . PRO A 1 154 ? 1.278 17.852 9.935 1.00 29.44 ? 374 PRO A CB 1 ATOM 1089 C CG . PRO A 1 154 ? 2.326 16.920 10.403 1.00 34.88 ? 374 PRO A CG 1 ATOM 1090 C CD . PRO A 1 154 ? 2.790 17.437 11.740 1.00 33.20 ? 374 PRO A CD 1 ATOM 1091 N N . SER A 1 155 ? -1.651 17.480 10.656 1.00 37.33 ? 375 SER A N 1 ATOM 1092 C CA . SER A 1 155 ? -2.955 16.845 10.916 1.00 40.84 ? 375 SER A CA 1 ATOM 1093 C C . SER A 1 155 ? -2.949 15.306 10.861 1.00 40.38 ? 375 SER A C 1 ATOM 1094 O O . SER A 1 155 ? -3.951 14.665 11.196 1.00 39.02 ? 375 SER A O 1 ATOM 1095 C CB . SER A 1 155 ? -3.994 17.382 9.933 1.00 35.65 ? 375 SER A CB 1 ATOM 1096 O OG . SER A 1 155 ? -3.848 16.743 8.676 1.00 33.36 ? 375 SER A OG 1 ATOM 1097 N N . ASP A 1 156 ? -1.831 14.724 10.428 1.00 39.52 ? 376 ASP A N 1 ATOM 1098 C CA . ASP A 1 156 ? -1.697 13.272 10.334 1.00 41.30 ? 376 ASP A CA 1 ATOM 1099 C C . ASP A 1 156 ? -1.720 12.655 11.729 1.00 44.01 ? 376 ASP A C 1 ATOM 1100 O O . ASP A 1 156 ? -0.891 12.984 12.583 1.00 38.74 ? 376 ASP A O 1 ATOM 1101 C CB . ASP A 1 156 ? -0.417 12.898 9.587 1.00 39.63 ? 376 ASP A CB 1 ATOM 1102 C CG . ASP A 1 156 ? -0.448 13.316 8.116 1.00 48.84 ? 376 ASP A CG 1 ATOM 1103 O OD1 . ASP A 1 156 ? 0.586 13.797 7.610 1.00 54.05 ? 376 ASP A OD1 1 ATOM 1104 O OD2 . ASP A 1 156 ? -1.502 13.171 7.462 1.00 46.69 ? 376 ASP A OD2 1 ATOM 1105 N N . ILE A 1 157 ? -2.692 11.778 11.963 1.00 41.73 ? 377 ILE A N 1 ATOM 1106 C CA . ILE A 1 157 ? -2.906 11.234 13.300 1.00 34.43 ? 377 ILE A CA 1 ATOM 1107 C C . ILE A 1 157 ? -3.688 9.933 13.250 1.00 36.33 ? 377 ILE A C 1 ATOM 1108 O O . ILE A 1 157 ? -4.298 9.596 12.232 1.00 41.06 ? 377 ILE A O 1 ATOM 1109 C CB . ILE A 1 157 ? -3.589 12.278 14.212 1.00 32.75 ? 377 ILE A CB 1 ATOM 1110 C CG1 . ILE A 1 157 ? -3.323 11.983 15.688 1.00 30.68 ? 377 ILE A CG1 1 ATOM 1111 C CG2 . ILE A 1 157 ? -5.075 12.429 13.884 1.00 31.70 ? 377 ILE A CG2 1 ATOM 1112 C CD1 . ILE A 1 157 ? -3.528 13.195 16.567 1.00 30.01 ? 377 ILE A CD1 1 ATOM 1113 N N . ALA A 1 158 ? -3.620 9.188 14.349 1.00 33.50 ? 378 ALA A N 1 ATOM 1114 C CA . ALA A 1 158 ? -4.390 7.978 14.541 1.00 30.00 ? 378 ALA A CA 1 ATOM 1115 C C . ALA A 1 158 ? -4.873 7.959 15.994 1.00 36.82 ? 378 ALA A C 1 ATOM 1116 O O . ALA A 1 158 ? -4.077 8.147 16.925 1.00 29.24 ? 378 ALA A O 1 ATOM 1117 C CB . ALA A 1 158 ? -3.534 6.755 14.248 1.00 28.81 ? 378 ALA A CB 1 ATOM 1118 N N . VAL A 1 159 ? -6.177 7.766 16.172 1.00 31.22 ? 379 VAL A N 1 ATOM 1119 C CA . VAL A 1 159 ? -6.777 7.670 17.492 1.00 31.02 ? 379 VAL A CA 1 ATOM 1120 C C . VAL A 1 159 ? -7.562 6.364 17.561 1.00 34.24 ? 379 VAL A C 1 ATOM 1121 O O . VAL A 1 159 ? -8.312 6.025 16.647 1.00 39.11 ? 379 VAL A O 1 ATOM 1122 C CB . VAL A 1 159 ? -7.697 8.871 17.803 1.00 35.85 ? 379 VAL A CB 1 ATOM 1123 C CG1 . VAL A 1 159 ? -8.163 8.836 19.252 1.00 30.02 ? 379 VAL A CG1 1 ATOM 1124 C CG2 . VAL A 1 159 ? -6.979 10.184 17.538 1.00 33.40 ? 379 VAL A CG2 1 ATOM 1125 N N . GLU A 1 160 ? -7.344 5.613 18.632 1.00 29.28 ? 380 GLU A N 1 ATOM 1126 C CA . GLU A 1 160 ? -8.020 4.353 18.847 1.00 34.19 ? 380 GLU A CA 1 ATOM 1127 C C . GLU A 1 160 ? -8.360 4.236 20.320 1.00 39.23 ? 380 GLU A C 1 ATOM 1128 O O . GLU A 1 160 ? -7.821 4.968 21.164 1.00 36.19 ? 380 GLU A O 1 ATOM 1129 C CB . GLU A 1 160 ? -7.117 3.187 18.439 1.00 45.33 ? 380 GLU A CB 1 ATOM 1130 C CG . GLU A 1 160 ? -7.011 2.979 16.942 1.00 52.50 ? 380 GLU A CG 1 ATOM 1131 C CD . GLU A 1 160 ? -5.943 1.980 16.557 1.00 60.43 ? 380 GLU A CD 1 ATOM 1132 O OE1 . GLU A 1 160 ? -5.898 0.884 17.152 1.00 64.37 ? 380 GLU A OE1 1 ATOM 1133 O OE2 . GLU A 1 160 ? -5.155 2.288 15.642 1.00 63.54 ? 380 GLU A OE2 1 ATOM 1134 N N . TRP A 1 161 ? -9.250 3.302 20.623 1.00 36.27 ? 381 TRP A N 1 ATOM 1135 C CA . TRP A 1 161 ? -9.683 3.066 21.986 1.00 28.60 ? 381 TRP A CA 1 ATOM 1136 C C . TRP A 1 161 ? -9.425 1.645 22.345 1.00 31.99 ? 381 TRP A C 1 ATOM 1137 O O . TRP A 1 161 ? -9.482 0.763 21.484 1.00 33.31 ? 381 TRP A O 1 ATOM 1138 C CB . TRP A 1 161 ? -11.170 3.328 22.112 1.00 26.35 ? 381 TRP A CB 1 ATOM 1139 C CG . TRP A 1 161 ? -11.573 4.779 22.186 1.00 24.79 ? 381 TRP A CG 1 ATOM 1140 C CD1 . TRP A 1 161 ? -11.974 5.598 21.145 1.00 27.44 ? 381 TRP A CD1 1 ATOM 1141 C CD2 . TRP A 1 161 ? -11.668 5.618 23.390 1.00 28.13 ? 381 TRP A CD2 1 ATOM 1142 N NE1 . TRP A 1 161 ? -12.291 6.853 21.602 1.00 32.01 ? 381 TRP A NE1 1 ATOM 1143 C CE2 . TRP A 1 161 ? -12.132 6.931 22.939 1.00 28.10 ? 381 TRP A CE2 1 ATOM 1144 C CE3 . TRP A 1 161 ? -11.422 5.419 24.747 1.00 31.13 ? 381 TRP A CE3 1 ATOM 1145 C CZ2 . TRP A 1 161 ? -12.346 7.979 23.820 1.00 27.88 ? 381 TRP A CZ2 1 ATOM 1146 C CZ3 . TRP A 1 161 ? -11.634 6.488 25.630 1.00 28.16 ? 381 TRP A CZ3 1 ATOM 1147 C CH2 . TRP A 1 161 ? -12.080 7.736 25.177 1.00 28.91 ? 381 TRP A CH2 1 ATOM 1148 N N . GLU A 1 162 ? -9.158 1.403 23.626 1.00 27.94 ? 382 GLU A N 1 ATOM 1149 C CA . GLU A 1 162 ? -8.979 0.051 24.138 1.00 31.43 ? 382 GLU A CA 1 ATOM 1150 C C . GLU A 1 162 ? -9.426 -0.052 25.592 1.00 34.34 ? 382 GLU A C 1 ATOM 1151 O O . GLU A 1 162 ? -9.642 0.958 26.254 1.00 28.77 ? 382 GLU A O 1 ATOM 1152 C CB . GLU A 1 162 ? -7.514 -0.384 24.026 1.00 33.40 ? 382 GLU A CB 1 ATOM 1153 C CG . GLU A 1 162 ? -6.587 0.342 24.989 1.00 38.61 ? 382 GLU A CG 1 ATOM 1154 C CD . GLU A 1 162 ? -5.171 -0.180 24.929 1.00 50.92 ? 382 GLU A CD 1 ATOM 1155 O OE1 . GLU A 1 162 ? -4.640 -0.574 25.991 1.00 59.70 ? 382 GLU A OE1 1 ATOM 1156 O OE2 . GLU A 1 162 ? -4.599 -0.208 23.818 1.00 44.71 ? 382 GLU A OE2 1 ATOM 1157 N N . SER A 1 163 ? -9.553 -1.290 26.060 1.00 37.88 ? 383 SER A N 1 ATOM 1158 C CA . SER A 1 163 ? -9.832 -1.622 27.451 1.00 38.88 ? 383 SER A CA 1 ATOM 1159 C C . SER A 1 163 ? -9.303 -3.030 27.682 1.00 37.23 ? 383 SER A C 1 ATOM 1160 O O . SER A 1 163 ? -9.455 -3.903 26.815 1.00 35.36 ? 383 SER A O 1 ATOM 1161 C CB . SER A 1 163 ? -11.336 -1.606 27.718 1.00 40.85 ? 383 SER A CB 1 ATOM 1162 O OG . SER A 1 163 ? -11.604 -1.786 29.094 1.00 37.76 ? 383 SER A OG 1 ATOM 1163 N N . ASN A 1 164 ? -8.684 -3.246 28.842 1.00 34.38 ? 384 ASN A N 1 ATOM 1164 C CA . ASN A 1 164 ? -8.087 -4.534 29.191 1.00 42.30 ? 384 ASN A CA 1 ATOM 1165 C C . ASN A 1 164 ? -7.232 -5.159 28.077 1.00 46.89 ? 384 ASN A C 1 ATOM 1166 O O . ASN A 1 164 ? -7.338 -6.361 27.799 1.00 45.62 ? 384 ASN A O 1 ATOM 1167 C CB . ASN A 1 164 ? -9.179 -5.511 29.640 1.00 51.70 ? 384 ASN A CB 1 ATOM 1168 C CG . ASN A 1 164 ? -9.606 -5.285 31.075 1.00 56.40 ? 384 ASN A CG 1 ATOM 1169 O OD1 . ASN A 1 164 ? -8.773 -5.218 31.977 1.00 59.57 ? 384 ASN A OD1 1 ATOM 1170 N ND2 . ASN A 1 164 ? -10.911 -5.180 31.295 1.00 61.93 ? 384 ASN A ND2 1 ATOM 1171 N N . GLY A 1 165 ? -6.405 -4.331 27.435 1.00 43.89 ? 385 GLY A N 1 ATOM 1172 C CA . GLY A 1 165 ? -5.569 -4.762 26.307 1.00 43.80 ? 385 GLY A CA 1 ATOM 1173 C C . GLY A 1 165 ? -6.303 -5.215 25.050 1.00 46.47 ? 385 GLY A C 1 ATOM 1174 O O . GLY A 1 165 ? -5.695 -5.768 24.139 1.00 49.63 ? 385 GLY A O 1 ATOM 1175 N N . GLN A 1 166 ? -7.612 -5.000 25.005 1.00 49.23 ? 386 GLN A N 1 ATOM 1176 C CA . GLN A 1 166 ? -8.410 -5.349 23.842 1.00 40.99 ? 386 GLN A CA 1 ATOM 1177 C C . GLN A 1 166 ? -8.948 -4.078 23.215 1.00 42.91 ? 386 GLN A C 1 ATOM 1178 O O . GLN A 1 166 ? -9.378 -3.169 23.940 1.00 40.00 ? 386 GLN A O 1 ATOM 1179 C CB . GLN A 1 166 ? -9.583 -6.256 24.228 1.00 45.75 ? 386 GLN A CB 1 ATOM 1180 C CG . GLN A 1 166 ? -9.211 -7.706 24.511 1.00 54.84 ? 386 GLN A CG 1 ATOM 1181 C CD . GLN A 1 166 ? -8.575 -8.398 23.321 1.00 62.11 ? 386 GLN A CD 1 ATOM 1182 O OE1 . GLN A 1 166 ? -7.461 -8.913 23.417 1.00 61.68 ? 386 GLN A OE1 1 ATOM 1183 N NE2 . GLN A 1 166 ? -9.274 -8.401 22.186 1.00 66.11 ? 386 GLN A NE2 1 ATOM 1184 N N . PRO A 1 167 ? -8.937 -4.008 21.867 1.00 34.49 ? 387 PRO A N 1 ATOM 1185 C CA . PRO A 1 167 ? -9.528 -2.865 21.184 1.00 33.68 ? 387 PRO A CA 1 ATOM 1186 C C . PRO A 1 167 ? -11.036 -2.766 21.443 1.00 35.18 ? 387 PRO A C 1 ATOM 1187 O O . PRO A 1 167 ? -11.732 -3.783 21.465 1.00 39.69 ? 387 PRO A O 1 ATOM 1188 C CB . PRO A 1 167 ? -9.254 -3.150 19.687 1.00 35.53 ? 387 PRO A CB 1 ATOM 1189 C CG . PRO A 1 167 ? -8.947 -4.610 19.600 1.00 32.36 ? 387 PRO A CG 1 ATOM 1190 C CD . PRO A 1 167 ? -8.355 -4.990 20.926 1.00 35.11 ? 387 PRO A CD 1 ATOM 1191 N N . GLU A 1 168 ? -11.506 -1.543 21.670 1.00 30.84 ? 388 GLU A N 1 ATOM 1192 C CA . GLU A 1 168 ? -12.929 -1.229 21.749 1.00 29.71 ? 388 GLU A CA 1 ATOM 1193 C C . GLU A 1 168 ? -13.264 -0.522 20.449 1.00 32.17 ? 388 GLU A C 1 ATOM 1194 O O . GLU A 1 168 ? -12.715 0.539 20.175 1.00 34.30 ? 388 GLU A O 1 ATOM 1195 C CB . GLU A 1 168 ? -13.201 -0.304 22.937 1.00 28.21 ? 388 GLU A CB 1 ATOM 1196 C CG . GLU A 1 168 ? -12.928 -0.941 24.300 1.00 32.69 ? 388 GLU A CG 1 ATOM 1197 C CD . GLU A 1 168 ? -13.993 -1.957 24.705 1.00 34.81 ? 388 GLU A CD 1 ATOM 1198 O OE1 . GLU A 1 168 ? -15.173 -1.787 24.324 1.00 34.32 ? 388 GLU A OE1 1 ATOM 1199 O OE2 . GLU A 1 168 ? -13.651 -2.932 25.408 1.00 43.72 ? 388 GLU A OE2 1 ATOM 1200 N N . ASN A 1 169 ? -14.139 -1.121 19.645 1.00 36.38 ? 389 ASN A N 1 ATOM 1201 C CA . ASN A 1 169 ? -14.412 -0.624 18.297 1.00 40.24 ? 389 ASN A CA 1 ATOM 1202 C C . ASN A 1 169 ? -15.633 0.305 18.138 1.00 39.54 ? 389 ASN A C 1 ATOM 1203 O O . ASN A 1 169 ? -15.855 0.853 17.050 1.00 39.74 ? 389 ASN A O 1 ATOM 1204 C CB . ASN A 1 169 ? -14.456 -1.789 17.290 1.00 41.44 ? 389 ASN A CB 1 ATOM 1205 C CG . ASN A 1 169 ? -13.061 -2.308 16.929 1.00 51.90 ? 389 ASN A CG 1 ATOM 1206 O OD1 . ASN A 1 169 ? -12.201 -1.553 16.466 1.00 60.76 ? 389 ASN A OD1 1 ATOM 1207 N ND2 . ASN A 1 169 ? -12.835 -3.600 17.138 1.00 39.52 ? 389 ASN A ND2 1 ATOM 1208 N N . ASN A 1 170 ? -16.406 0.504 19.208 1.00 30.98 ? 390 ASN A N 1 ATOM 1209 C CA . ASN A 1 170 ? -17.627 1.321 19.108 1.00 31.40 ? 390 ASN A CA 1 ATOM 1210 C C . ASN A 1 170 ? -17.407 2.827 19.311 1.00 27.99 ? 390 ASN A C 1 ATOM 1211 O O . ASN A 1 170 ? -18.106 3.489 20.085 1.00 34.54 ? 390 ASN A O 1 ATOM 1212 C CB . ASN A 1 170 ? -18.724 0.793 20.029 1.00 28.82 ? 390 ASN A CB 1 ATOM 1213 C CG . ASN A 1 170 ? -20.109 1.250 19.613 1.00 37.12 ? 390 ASN A CG 1 ATOM 1214 O OD1 . ASN A 1 170 ? -20.551 1.019 18.480 1.00 40.05 ? 390 ASN A OD1 1 ATOM 1215 N ND2 . ASN A 1 170 ? -20.815 1.880 20.539 1.00 38.04 ? 390 ASN A ND2 1 ATOM 1216 N N . TYR A 1 171 ? -16.435 3.370 18.593 1.00 30.79 ? 391 TYR A N 1 ATOM 1217 C CA . TYR A 1 171 ? -16.163 4.797 18.637 1.00 30.75 ? 391 TYR A CA 1 ATOM 1218 C C . TYR A 1 171 ? -16.291 5.450 17.266 1.00 33.15 ? 391 TYR A C 1 ATOM 1219 O O . TYR A 1 171 ? -16.310 4.754 16.240 1.00 33.62 ? 391 TYR A O 1 ATOM 1220 C CB . TYR A 1 171 ? -14.775 5.054 19.243 1.00 38.11 ? 391 TYR A CB 1 ATOM 1221 C CG . TYR A 1 171 ? -13.605 4.532 18.427 1.00 44.41 ? 391 TYR A CG 1 ATOM 1222 C CD1 . TYR A 1 171 ? -12.976 5.339 17.470 1.00 42.83 ? 391 TYR A CD1 1 ATOM 1223 C CD2 . TYR A 1 171 ? -13.111 3.240 18.628 1.00 44.55 ? 391 TYR A CD2 1 ATOM 1224 C CE1 . TYR A 1 171 ? -11.895 4.865 16.732 1.00 44.44 ? 391 TYR A CE1 1 ATOM 1225 C CE2 . TYR A 1 171 ? -12.035 2.756 17.896 1.00 40.16 ? 391 TYR A CE2 1 ATOM 1226 C CZ . TYR A 1 171 ? -11.433 3.571 16.950 1.00 46.23 ? 391 TYR A CZ 1 ATOM 1227 O OH . TYR A 1 171 ? -10.368 3.095 16.229 1.00 45.15 ? 391 TYR A OH 1 ATOM 1228 N N . LYS A 1 172 ? -16.409 6.781 17.262 1.00 32.32 ? 392 LYS A N 1 ATOM 1229 C CA . LYS A 1 172 ? -16.264 7.585 16.039 1.00 36.38 ? 392 LYS A CA 1 ATOM 1230 C C . LYS A 1 172 ? -15.373 8.778 16.349 1.00 32.29 ? 392 LYS A C 1 ATOM 1231 O O . LYS A 1 172 ? -15.412 9.325 17.454 1.00 32.10 ? 392 LYS A O 1 ATOM 1232 C CB . LYS A 1 172 ? -17.615 8.080 15.498 1.00 32.37 ? 392 LYS A CB 1 ATOM 1233 C CG . LYS A 1 172 ? -18.576 6.994 15.045 1.00 32.82 ? 392 LYS A CG 1 ATOM 1234 C CD . LYS A 1 172 ? -18.269 6.473 13.651 1.00 38.63 ? 392 LYS A CD 1 ATOM 1235 C CE . LYS A 1 172 ? -19.358 5.500 13.218 1.00 37.31 ? 392 LYS A CE 1 ATOM 1236 N NZ . LYS A 1 172 ? -18.900 4.582 12.147 1.00 41.59 ? 392 LYS A NZ 1 ATOM 1237 N N . THR A 1 173 ? -14.555 9.171 15.386 1.00 29.84 ? 393 THR A N 1 ATOM 1238 C CA . THR A 1 173 ? -13.673 10.312 15.587 1.00 31.44 ? 393 THR A CA 1 ATOM 1239 C C . THR A 1 173 ? -13.980 11.388 14.563 1.00 33.34 ? 393 THR A C 1 ATOM 1240 O O . THR A 1 173 ? -14.173 11.095 13.381 1.00 35.10 ? 393 THR A O 1 ATOM 1241 C CB . THR A 1 173 ? -12.191 9.891 15.516 1.00 34.33 ? 393 THR A CB 1 ATOM 1242 O OG1 . THR A 1 173 ? -11.964 8.840 16.456 1.00 31.17 ? 393 THR A OG1 1 ATOM 1243 C CG2 . THR A 1 173 ? -11.265 11.058 15.859 1.00 34.47 ? 393 THR A CG2 1 ATOM 1244 N N . THR A 1 174 ? -14.045 12.634 15.012 1.00 28.53 ? 394 THR A N 1 ATOM 1245 C CA . THR A 1 174 ? -14.267 13.730 14.087 1.00 34.87 ? 394 THR A CA 1 ATOM 1246 C C . THR A 1 174 ? -13.077 13.849 13.129 1.00 41.36 ? 394 THR A C 1 ATOM 1247 O O . THR A 1 174 ? -11.984 13.355 13.429 1.00 44.17 ? 394 THR A O 1 ATOM 1248 C CB . THR A 1 174 ? -14.466 15.063 14.823 1.00 35.06 ? 394 THR A CB 1 ATOM 1249 O OG1 . THR A 1 174 ? -13.252 15.428 15.479 1.00 32.38 ? 394 THR A OG1 1 ATOM 1250 C CG2 . THR A 1 174 ? -15.577 14.948 15.852 1.00 34.83 ? 394 THR A CG2 1 ATOM 1251 N N . PRO A 1 175 ? -13.290 14.457 11.949 1.00 44.31 ? 395 PRO A N 1 ATOM 1252 C CA . PRO A 1 175 ? -12.112 14.879 11.199 1.00 42.74 ? 395 PRO A CA 1 ATOM 1253 C C . PRO A 1 175 ? -11.339 15.912 12.023 1.00 43.68 ? 395 PRO A C 1 ATOM 1254 O O . PRO A 1 175 ? -11.900 16.473 12.969 1.00 42.76 ? 395 PRO A O 1 ATOM 1255 C CB . PRO A 1 175 ? -12.716 15.523 9.944 1.00 46.56 ? 395 PRO A CB 1 ATOM 1256 C CG . PRO A 1 175 ? -13.987 14.772 9.737 1.00 47.16 ? 395 PRO A CG 1 ATOM 1257 C CD . PRO A 1 175 ? -14.517 14.523 11.130 1.00 40.89 ? 395 PRO A CD 1 ATOM 1258 N N . PRO A 1 176 ? -10.049 16.138 11.703 1.00 39.63 ? 396 PRO A N 1 ATOM 1259 C CA . PRO A 1 176 ? -9.349 17.205 12.401 1.00 33.47 ? 396 PRO A CA 1 ATOM 1260 C C . PRO A 1 176 ? -9.856 18.560 11.919 1.00 34.54 ? 396 PRO A C 1 ATOM 1261 O O . PRO A 1 176 ? -10.251 18.699 10.757 1.00 35.12 ? 396 PRO A O 1 ATOM 1262 C CB . PRO A 1 176 ? -7.885 16.993 11.996 1.00 33.77 ? 396 PRO A CB 1 ATOM 1263 C CG . PRO A 1 176 ? -7.826 15.611 11.441 1.00 36.89 ? 396 PRO A CG 1 ATOM 1264 C CD . PRO A 1 176 ? -9.155 15.419 10.786 1.00 36.23 ? 396 PRO A CD 1 ATOM 1265 N N . VAL A 1 177 ? -9.868 19.540 12.812 1.00 31.66 ? 397 VAL A N 1 ATOM 1266 C CA . VAL A 1 177 ? -10.346 20.877 12.479 1.00 33.78 ? 397 VAL A CA 1 ATOM 1267 C C . VAL A 1 177 ? -9.207 21.873 12.712 1.00 43.39 ? 397 VAL A C 1 ATOM 1268 O O . VAL A 1 177 ? -8.590 21.884 13.790 1.00 35.09 ? 397 VAL A O 1 ATOM 1269 C CB . VAL A 1 177 ? -11.587 21.256 13.318 1.00 39.86 ? 397 VAL A CB 1 ATOM 1270 C CG1 . VAL A 1 177 ? -11.995 22.710 13.086 1.00 38.04 ? 397 VAL A CG1 1 ATOM 1271 C CG2 . VAL A 1 177 ? -12.751 20.322 13.009 1.00 38.11 ? 397 VAL A CG2 1 ATOM 1272 N N . LEU A 1 178 ? -8.915 22.689 11.697 1.00 39.42 ? 398 LEU A N 1 ATOM 1273 C CA . LEU A 1 178 ? -7.858 23.689 11.807 1.00 37.17 ? 398 LEU A CA 1 ATOM 1274 C C . LEU A 1 178 ? -8.250 24.740 12.823 1.00 36.50 ? 398 LEU A C 1 ATOM 1275 O O . LEU A 1 178 ? -9.241 25.436 12.632 1.00 44.22 ? 398 LEU A O 1 ATOM 1276 C CB . LEU A 1 178 ? -7.581 24.353 10.455 1.00 38.81 ? 398 LEU A CB 1 ATOM 1277 C CG . LEU A 1 178 ? -6.597 25.533 10.462 1.00 41.27 ? 398 LEU A CG 1 ATOM 1278 C CD1 . LEU A 1 178 ? -5.197 25.112 10.902 1.00 37.64 ? 398 LEU A CD1 1 ATOM 1279 C CD2 . LEU A 1 178 ? -6.547 26.187 9.090 1.00 38.80 ? 398 LEU A CD2 1 ATOM 1280 N N . ASP A 1 179 ? -7.474 24.845 13.899 1.00 36.06 ? 399 ASP A N 1 ATOM 1281 C CA . ASP A 1 179 ? -7.774 25.778 14.986 1.00 38.33 ? 399 ASP A CA 1 ATOM 1282 C C . ASP A 1 179 ? -7.210 27.154 14.649 1.00 45.88 ? 399 ASP A C 1 ATOM 1283 O O . ASP A 1 179 ? -6.613 27.346 13.589 1.00 46.66 ? 399 ASP A O 1 ATOM 1284 C CB . ASP A 1 179 ? -7.195 25.271 16.315 1.00 36.76 ? 399 ASP A CB 1 ATOM 1285 C CG . ASP A 1 179 ? -8.091 25.581 17.522 1.00 45.58 ? 399 ASP A CG 1 ATOM 1286 O OD1 . ASP A 1 179 ? -8.836 26.594 17.515 1.00 46.54 ? 399 ASP A OD1 1 ATOM 1287 O OD2 . ASP A 1 179 ? -8.040 24.802 18.497 1.00 47.69 ? 399 ASP A OD2 1 ATOM 1288 N N . SER A 1 180 ? -7.391 28.107 15.557 1.00 47.97 ? 400 SER A N 1 ATOM 1289 C CA . SER A 1 180 ? -7.067 29.500 15.269 1.00 49.24 ? 400 SER A CA 1 ATOM 1290 C C . SER A 1 180 ? -5.586 29.829 15.487 1.00 47.43 ? 400 SER A C 1 ATOM 1291 O O . SER A 1 180 ? -5.115 30.883 15.057 1.00 48.05 ? 400 SER A O 1 ATOM 1292 C CB . SER A 1 180 ? -7.972 30.438 16.076 1.00 43.25 ? 400 SER A CB 1 ATOM 1293 O OG . SER A 1 180 ? -7.619 30.429 17.447 1.00 49.24 ? 400 SER A OG 1 ATOM 1294 N N . ASP A 1 181 ? -4.860 28.929 16.150 1.00 47.50 ? 401 ASP A N 1 ATOM 1295 C CA . ASP A 1 181 ? -3.416 29.090 16.337 1.00 37.65 ? 401 ASP A CA 1 ATOM 1296 C C . ASP A 1 181 ? -2.598 28.341 15.286 1.00 31.24 ? 401 ASP A C 1 ATOM 1297 O O . ASP A 1 181 ? -1.378 28.259 15.382 1.00 34.32 ? 401 ASP A O 1 ATOM 1298 C CB . ASP A 1 181 ? -2.991 28.680 17.749 1.00 40.47 ? 401 ASP A CB 1 ATOM 1299 C CG . ASP A 1 181 ? -3.115 27.178 17.997 1.00 48.08 ? 401 ASP A CG 1 ATOM 1300 O OD1 . ASP A 1 181 ? -3.463 26.420 17.058 1.00 39.11 ? 401 ASP A OD1 1 ATOM 1301 O OD2 . ASP A 1 181 ? -2.865 26.764 19.153 1.00 46.52 ? 401 ASP A OD2 1 ATOM 1302 N N . GLY A 1 182 ? -3.274 27.783 14.292 1.00 33.72 ? 402 GLY A N 1 ATOM 1303 C CA . GLY A 1 182 ? -2.586 27.112 13.195 1.00 35.81 ? 402 GLY A CA 1 ATOM 1304 C C . GLY A 1 182 ? -2.346 25.630 13.417 1.00 39.56 ? 402 GLY A C 1 ATOM 1305 O O . GLY A 1 182 ? -1.854 24.946 12.520 1.00 28.49 ? 402 GLY A O 1 ATOM 1306 N N . SER A 1 183 ? -2.680 25.140 14.612 1.00 40.50 ? 403 SER A N 1 ATOM 1307 C CA . SER A 1 183 ? -2.642 23.706 14.904 1.00 40.03 ? 403 SER A CA 1 ATOM 1308 C C . SER A 1 183 ? -4.017 23.074 14.688 1.00 39.56 ? 403 SER A C 1 ATOM 1309 O O . SER A 1 183 ? -4.956 23.739 14.247 1.00 36.26 ? 403 SER A O 1 ATOM 1310 C CB . SER A 1 183 ? -2.196 23.474 16.342 1.00 40.40 ? 403 SER A CB 1 ATOM 1311 O OG . SER A 1 183 ? -3.257 23.790 17.223 1.00 39.64 ? 403 SER A OG 1 ATOM 1312 N N . PHE A 1 184 ? -4.132 21.786 15.002 1.00 39.01 ? 404 PHE A N 1 ATOM 1313 C CA . PHE A 1 184 ? -5.388 21.066 14.832 1.00 31.17 ? 404 PHE A CA 1 ATOM 1314 C C . PHE A 1 184 ? -5.948 20.535 16.154 1.00 38.58 ? 404 PHE A C 1 ATOM 1315 O O . PHE A 1 184 ? -5.240 20.457 17.174 1.00 31.64 ? 404 PHE A O 1 ATOM 1316 C CB . PHE A 1 184 ? -5.227 19.917 13.843 1.00 32.71 ? 404 PHE A CB 1 ATOM 1317 C CG . PHE A 1 184 ? -5.041 20.345 12.414 1.00 34.65 ? 404 PHE A CG 1 ATOM 1318 C CD1 . PHE A 1 184 ? -3.771 20.645 11.916 1.00 38.65 ? 404 PHE A CD1 1 ATOM 1319 C CD2 . PHE A 1 184 ? -6.125 20.401 11.547 1.00 34.91 ? 404 PHE A CD2 1 ATOM 1320 C CE1 . PHE A 1 184 ? -3.600 21.022 10.587 1.00 36.74 ? 404 PHE A CE1 1 ATOM 1321 C CE2 . PHE A 1 184 ? -5.959 20.777 10.218 1.00 34.11 ? 404 PHE A CE2 1 ATOM 1322 C CZ . PHE A 1 184 ? -4.694 21.092 9.739 1.00 34.19 ? 404 PHE A CZ 1 ATOM 1323 N N . PHE A 1 185 ? -7.236 20.202 16.119 1.00 38.81 ? 405 PHE A N 1 ATOM 1324 C CA . PHE A 1 185 ? -7.900 19.501 17.204 1.00 36.62 ? 405 PHE A CA 1 ATOM 1325 C C . PHE A 1 185 ? -8.943 18.542 16.651 1.00 38.26 ? 405 PHE A C 1 ATOM 1326 O O . PHE A 1 185 ? -9.433 18.699 15.518 1.00 36.70 ? 405 PHE A O 1 ATOM 1327 C CB . PHE A 1 185 ? -8.540 20.472 18.199 1.00 42.08 ? 405 PHE A CB 1 ATOM 1328 C CG . PHE A 1 185 ? -9.809 21.105 17.704 1.00 44.78 ? 405 PHE A CG 1 ATOM 1329 C CD1 . PHE A 1 185 ? -11.044 20.508 17.948 1.00 41.00 ? 405 PHE A CD1 1 ATOM 1330 C CD2 . PHE A 1 185 ? -9.770 22.301 16.999 1.00 45.78 ? 405 PHE A CD2 1 ATOM 1331 C CE1 . PHE A 1 185 ? -12.213 21.084 17.485 1.00 43.71 ? 405 PHE A CE1 1 ATOM 1332 C CE2 . PHE A 1 185 ? -10.937 22.889 16.541 1.00 46.95 ? 405 PHE A CE2 1 ATOM 1333 C CZ . PHE A 1 185 ? -12.160 22.280 16.784 1.00 51.72 ? 405 PHE A CZ 1 ATOM 1334 N N . LEU A 1 186 ? -9.263 17.536 17.457 1.00 30.67 ? 406 LEU A N 1 ATOM 1335 C CA . LEU A 1 186 ? -10.322 16.606 17.131 1.00 32.94 ? 406 LEU A CA 1 ATOM 1336 C C . LEU A 1 186 ? -10.900 16.069 18.424 1.00 38.01 ? 406 LEU A C 1 ATOM 1337 O O . LEU A 1 186 ? -10.303 16.217 19.489 1.00 30.40 ? 406 LEU A O 1 ATOM 1338 C CB . LEU A 1 186 ? -9.807 15.463 16.247 1.00 32.02 ? 406 LEU A CB 1 ATOM 1339 C CG . LEU A 1 186 ? -8.751 14.444 16.715 1.00 30.09 ? 406 LEU A CG 1 ATOM 1340 C CD1 . LEU A 1 186 ? -9.232 13.584 17.889 1.00 26.53 ? 406 LEU A CD1 1 ATOM 1341 C CD2 . LEU A 1 186 ? -8.360 13.547 15.543 1.00 21.89 ? 406 LEU A CD2 1 ATOM 1342 N N . ALA A 1 187 ? -12.069 15.452 18.327 1.00 38.92 ? 407 ALA A N 1 ATOM 1343 C CA . ALA A 1 187 ? -12.629 14.733 19.449 1.00 37.56 ? 407 ALA A CA 1 ATOM 1344 C C . ALA A 1 187 ? -12.953 13.325 19.003 1.00 35.37 ? 407 ALA A C 1 ATOM 1345 O O . ALA A 1 187 ? -13.454 13.115 17.892 1.00 37.68 ? 407 ALA A O 1 ATOM 1346 C CB . ALA A 1 187 ? -13.865 15.436 19.962 1.00 41.15 ? 407 ALA A CB 1 ATOM 1347 N N . SER A 1 188 ? -12.634 12.356 19.849 1.00 27.70 ? 408 SER A N 1 ATOM 1348 C CA . SER A 1 188 ? -13.050 10.981 19.606 1.00 28.48 ? 408 SER A CA 1 ATOM 1349 C C . SER A 1 188 ? -14.009 10.573 20.716 1.00 31.68 ? 408 SER A C 1 ATOM 1350 O O . SER A 1 188 ? -13.789 10.884 21.885 1.00 28.31 ? 408 SER A O 1 ATOM 1351 C CB . SER A 1 188 ? -11.845 10.040 19.506 1.00 25.67 ? 408 SER A CB 1 ATOM 1352 O OG . SER A 1 188 ? -12.262 8.698 19.351 1.00 26.85 ? 408 SER A OG 1 ATOM 1353 N N . LYS A 1 189 ? -15.091 9.903 20.343 1.00 31.52 ? 409 LYS A N 1 ATOM 1354 C CA . LYS A 1 189 ? -16.120 9.555 21.305 1.00 29.99 ? 409 LYS A CA 1 ATOM 1355 C C . LYS A 1 189 ? -16.278 8.057 21.298 1.00 30.20 ? 409 LYS A C 1 ATOM 1356 O O . LYS A 1 189 ? -16.525 7.456 20.239 1.00 28.55 ? 409 LYS A O 1 ATOM 1357 C CB . LYS A 1 189 ? -17.446 10.241 20.942 1.00 28.46 ? 409 LYS A CB 1 ATOM 1358 C CG . LYS A 1 189 ? -18.660 9.808 21.760 1.00 23.12 ? 409 LYS A CG 1 ATOM 1359 C CD . LYS A 1 189 ? -19.901 10.671 21.492 1.00 23.71 ? 409 LYS A CD 1 ATOM 1360 C CE . LYS A 1 189 ? -20.357 10.641 20.037 1.00 24.50 ? 409 LYS A CE 1 ATOM 1361 N NZ . LYS A 1 189 ? -21.051 9.381 19.679 1.00 27.48 ? 409 LYS A NZ 1 ATOM 1362 N N . LEU A 1 190 ? -16.119 7.451 22.469 1.00 19.62 ? 410 LEU A N 1 ATOM 1363 C CA . LEU A 1 190 ? -16.406 6.021 22.615 1.00 22.12 ? 410 LEU A CA 1 ATOM 1364 C C . LEU A 1 190 ? -17.713 5.777 23.365 1.00 23.63 ? 410 LEU A C 1 ATOM 1365 O O . LEU A 1 190 ? -17.919 6.318 24.449 1.00 29.51 ? 410 LEU A O 1 ATOM 1366 C CB . LEU A 1 190 ? -15.231 5.274 23.274 1.00 21.32 ? 410 LEU A CB 1 ATOM 1367 C CG . LEU A 1 190 ? -15.413 3.780 23.609 1.00 28.31 ? 410 LEU A CG 1 ATOM 1368 C CD1 . LEU A 1 190 ? -15.332 2.891 22.367 1.00 27.16 ? 410 LEU A CD1 1 ATOM 1369 C CD2 . LEU A 1 190 ? -14.390 3.348 24.650 1.00 26.31 ? 410 LEU A CD2 1 ATOM 1370 N N . THR A 1 191 ? -18.576 4.944 22.790 1.00 28.25 ? 411 THR A N 1 ATOM 1371 C CA . THR A 1 191 ? -19.909 4.680 23.339 1.00 29.23 ? 411 THR A CA 1 ATOM 1372 C C . THR A 1 191 ? -19.908 3.302 24.011 1.00 29.70 ? 411 THR A C 1 ATOM 1373 O O . THR A 1 191 ? -19.764 2.290 23.338 1.00 30.08 ? 411 THR A O 1 ATOM 1374 C CB . THR A 1 191 ? -20.998 4.794 22.231 1.00 25.53 ? 411 THR A CB 1 ATOM 1375 O OG1 . THR A 1 191 ? -21.074 6.153 21.787 1.00 19.37 ? 411 THR A OG1 1 ATOM 1376 C CG2 . THR A 1 191 ? -22.395 4.369 22.742 1.00 24.12 ? 411 THR A CG2 1 ATOM 1377 N N . VAL A 1 192 ? -20.029 3.281 25.342 1.00 25.82 ? 412 VAL A N 1 ATOM 1378 C CA . VAL A 1 192 ? -20.064 2.027 26.116 1.00 25.31 ? 412 VAL A CA 1 ATOM 1379 C C . VAL A 1 192 ? -21.431 1.802 26.796 1.00 23.69 ? 412 VAL A C 1 ATOM 1380 O O . VAL A 1 192 ? -22.137 2.757 27.097 1.00 25.51 ? 412 VAL A O 1 ATOM 1381 C CB . VAL A 1 192 ? -18.916 1.963 27.156 1.00 27.57 ? 412 VAL A CB 1 ATOM 1382 C CG1 . VAL A 1 192 ? -17.560 2.053 26.466 1.00 27.36 ? 412 VAL A CG1 1 ATOM 1383 C CG2 . VAL A 1 192 ? -19.026 3.101 28.148 1.00 21.75 ? 412 VAL A CG2 1 ATOM 1384 N N . ASP A 1 193 ? -21.813 0.542 27.007 1.00 23.25 ? 413 ASP A N 1 ATOM 1385 C CA . ASP A 1 193 ? -22.980 0.219 27.835 1.00 29.39 ? 413 ASP A CA 1 ATOM 1386 C C . ASP A 1 193 ? -22.770 0.903 29.194 1.00 28.33 ? 413 ASP A C 1 ATOM 1387 O O . ASP A 1 193 ? -21.645 0.943 29.686 1.00 23.95 ? 413 ASP A O 1 ATOM 1388 C CB . ASP A 1 193 ? -23.079 -1.291 28.068 1.00 33.17 ? 413 ASP A CB 1 ATOM 1389 C CG . ASP A 1 193 ? -23.647 -2.050 26.879 1.00 38.08 ? 413 ASP A CG 1 ATOM 1390 O OD1 . ASP A 1 193 ? -24.087 -3.197 27.092 1.00 44.64 ? 413 ASP A OD1 1 ATOM 1391 O OD2 . ASP A 1 193 ? -23.658 -1.526 25.742 1.00 47.87 ? 413 ASP A OD2 1 ATOM 1392 N N . LYS A 1 194 ? -23.832 1.442 29.778 1.00 28.32 ? 414 LYS A N 1 ATOM 1393 C CA . LYS A 1 194 ? -23.710 2.184 31.027 1.00 37.77 ? 414 LYS A CA 1 ATOM 1394 C C . LYS A 1 194 ? -23.175 1.261 32.117 1.00 34.83 ? 414 LYS A C 1 ATOM 1395 O O . LYS A 1 194 ? -22.323 1.665 32.903 1.00 36.01 ? 414 LYS A O 1 ATOM 1396 C CB . LYS A 1 194 ? -25.049 2.816 31.419 1.00 36.73 ? 414 LYS A CB 1 ATOM 1397 C CG . LYS A 1 194 ? -25.021 3.633 32.706 1.00 34.32 ? 414 LYS A CG 1 ATOM 1398 C CD . LYS A 1 194 ? -26.222 4.556 32.805 1.00 31.37 ? 414 LYS A CD 1 ATOM 1399 C CE . LYS A 1 194 ? -27.537 3.791 32.882 1.00 27.20 ? 414 LYS A CE 1 ATOM 1400 N NZ . LYS A 1 194 ? -28.650 4.777 32.887 1.00 26.59 ? 414 LYS A NZ 1 ATOM 1401 N N . SER A 1 195 ? -23.658 0.016 32.122 1.00 41.82 ? 415 SER A N 1 ATOM 1402 C CA . SER A 1 195 ? -23.198 -1.022 33.055 1.00 42.40 ? 415 SER A CA 1 ATOM 1403 C C . SER A 1 195 ? -21.680 -1.193 33.018 1.00 45.54 ? 415 SER A C 1 ATOM 1404 O O . SER A 1 195 ? -21.023 -1.185 34.072 1.00 31.69 ? 415 SER A O 1 ATOM 1405 C CB . SER A 1 195 ? -23.899 -2.353 32.783 1.00 36.20 ? 415 SER A CB 1 ATOM 1406 O OG . SER A 1 195 ? -23.645 -2.806 31.473 1.00 49.81 ? 415 SER A OG 1 ATOM 1407 N N . ARG A 1 196 ? -21.128 -1.311 31.807 1.00 32.78 ? 416 ARG A N 1 ATOM 1408 C CA . ARG A 1 196 ? -19.684 -1.457 31.623 1.00 37.19 ? 416 ARG A CA 1 ATOM 1409 C C . ARG A 1 196 ? -18.923 -0.298 32.266 1.00 37.85 ? 416 ARG A C 1 ATOM 1410 O O . ARG A 1 196 ? -17.860 -0.495 32.861 1.00 42.56 ? 416 ARG A O 1 ATOM 1411 C CB . ARG A 1 196 ? -19.325 -1.582 30.135 1.00 38.86 ? 416 ARG A CB 1 ATOM 1412 C CG . ARG A 1 196 ? -19.654 -2.935 29.523 1.00 35.40 ? 416 ARG A CG 1 ATOM 1413 C CD . ARG A 1 196 ? -18.982 -3.103 28.170 1.00 30.88 ? 416 ARG A CD 1 ATOM 1414 N NE . ARG A 1 196 ? -17.543 -3.338 28.322 1.00 31.87 ? 416 ARG A NE 1 ATOM 1415 C CZ . ARG A 1 196 ? -16.612 -2.944 27.460 1.00 34.30 ? 416 ARG A CZ 1 ATOM 1416 N NH1 . ARG A 1 196 ? -16.950 -2.270 26.366 1.00 35.16 ? 416 ARG A NH1 1 ATOM 1417 N NH2 . ARG A 1 196 ? -15.338 -3.213 27.699 1.00 40.28 ? 416 ARG A NH2 1 ATOM 1418 N N . TRP A 1 197 ? -19.486 0.904 32.152 1.00 36.65 ? 417 TRP A N 1 ATOM 1419 C CA . TRP A 1 197 ? -18.929 2.083 32.793 1.00 28.69 ? 417 TRP A CA 1 ATOM 1420 C C . TRP A 1 197 ? -19.097 2.054 34.294 1.00 31.03 ? 417 TRP A C 1 ATOM 1421 O O . TRP A 1 197 ? -18.177 2.410 35.027 1.00 28.13 ? 417 TRP A O 1 ATOM 1422 C CB . TRP A 1 197 ? -19.562 3.332 32.224 1.00 25.54 ? 417 TRP A CB 1 ATOM 1423 C CG . TRP A 1 197 ? -19.085 4.591 32.891 1.00 23.68 ? 417 TRP A CG 1 ATOM 1424 C CD1 . TRP A 1 197 ? -19.806 5.441 33.729 1.00 25.58 ? 417 TRP A CD1 1 ATOM 1425 C CD2 . TRP A 1 197 ? -17.755 5.194 32.793 1.00 23.35 ? 417 TRP A CD2 1 ATOM 1426 N NE1 . TRP A 1 197 ? -19.029 6.494 34.146 1.00 25.28 ? 417 TRP A NE1 1 ATOM 1427 C CE2 . TRP A 1 197 ? -17.791 6.408 33.632 1.00 23.00 ? 417 TRP A CE2 1 ATOM 1428 C CE3 . TRP A 1 197 ? -16.577 4.859 32.140 1.00 22.05 ? 417 TRP A CE3 1 ATOM 1429 C CZ2 . TRP A 1 197 ? -16.690 7.241 33.770 1.00 22.81 ? 417 TRP A CZ2 1 ATOM 1430 C CZ3 . TRP A 1 197 ? -15.472 5.706 32.286 1.00 23.59 ? 417 TRP A CZ3 1 ATOM 1431 C CH2 . TRP A 1 197 ? -15.527 6.867 33.087 1.00 25.18 ? 417 TRP A CH2 1 ATOM 1432 N N . GLN A 1 198 ? -20.266 1.630 34.768 1.00 32.32 ? 418 GLN A N 1 ATOM 1433 C CA . GLN A 1 198 ? -20.560 1.668 36.207 1.00 32.80 ? 418 GLN A CA 1 ATOM 1434 C C . GLN A 1 198 ? -19.789 0.602 36.972 1.00 35.03 ? 418 GLN A C 1 ATOM 1435 O O . GLN A 1 198 ? -19.544 0.749 38.172 1.00 45.26 ? 418 GLN A O 1 ATOM 1436 C CB . GLN A 1 198 ? -22.066 1.527 36.482 1.00 28.07 ? 418 GLN A CB 1 ATOM 1437 C CG . GLN A 1 198 ? -22.877 2.807 36.339 1.00 31.35 ? 418 GLN A CG 1 ATOM 1438 C CD . GLN A 1 198 ? -22.474 3.915 37.303 1.00 30.07 ? 418 GLN A CD 1 ATOM 1439 O OE1 . GLN A 1 198 ? -22.318 5.060 36.897 1.00 37.66 ? 418 GLN A OE1 1 ATOM 1440 N NE2 . GLN A 1 198 ? -22.317 3.583 38.580 1.00 28.11 ? 418 GLN A NE2 1 ATOM 1441 N N . GLN A 1 199 ? -19.414 -0.461 36.272 1.00 31.39 ? 419 GLN A N 1 ATOM 1442 C CA . GLN A 1 199 ? -18.659 -1.574 36.852 1.00 33.86 ? 419 GLN A CA 1 ATOM 1443 C C . GLN A 1 199 ? -17.177 -1.298 37.088 1.00 36.64 ? 419 GLN A C 1 ATOM 1444 O O . GLN A 1 199 ? -16.463 -2.186 37.548 1.00 39.40 ? 419 GLN A O 1 ATOM 1445 C CB . GLN A 1 199 ? -18.783 -2.814 35.974 1.00 33.61 ? 419 GLN A CB 1 ATOM 1446 C CG . GLN A 1 199 ? -20.123 -3.503 36.083 1.00 41.18 ? 419 GLN A CG 1 ATOM 1447 C CD . GLN A 1 199 ? -20.323 -4.572 35.030 1.00 54.88 ? 419 GLN A CD 1 ATOM 1448 O OE1 . GLN A 1 199 ? -19.465 -4.791 34.167 1.00 62.01 ? 419 GLN A OE1 1 ATOM 1449 N NE2 . GLN A 1 199 ? -21.466 -5.246 35.091 1.00 54.89 ? 419 GLN A NE2 1 ATOM 1450 N N . GLY A 1 200 ? -16.708 -0.095 36.758 1.00 32.24 ? 420 GLY A N 1 ATOM 1451 C CA . GLY A 1 200 ? -15.331 0.297 37.065 1.00 36.59 ? 420 GLY A CA 1 ATOM 1452 C C . GLY A 1 200 ? -14.279 0.015 36.004 1.00 38.03 ? 420 GLY A C 1 ATOM 1453 O O . GLY A 1 200 ? -13.094 0.293 36.205 1.00 35.69 ? 420 GLY A O 1 ATOM 1454 N N . ASN A 1 201 ? -14.704 -0.527 34.868 1.00 37.53 ? 421 ASN A N 1 ATOM 1455 C CA . ASN A 1 201 ? -13.792 -0.758 33.752 1.00 31.23 ? 421 ASN A CA 1 ATOM 1456 C C . ASN A 1 201 ? -12.988 0.467 33.329 1.00 25.60 ? 421 ASN A C 1 ATOM 1457 O O . ASN A 1 201 ? -13.505 1.588 33.263 1.00 26.63 ? 421 ASN A O 1 ATOM 1458 C CB . ASN A 1 201 ? -14.560 -1.326 32.573 1.00 31.30 ? 421 ASN A CB 1 ATOM 1459 C CG . ASN A 1 201 ? -15.044 -2.723 32.839 1.00 30.21 ? 421 ASN A CG 1 ATOM 1460 O OD1 . ASN A 1 201 ? -14.241 -3.628 33.047 1.00 32.37 ? 421 ASN A OD1 1 ATOM 1461 N ND2 . ASN A 1 201 ? -16.359 -2.916 32.828 1.00 32.66 ? 421 ASN A ND2 1 ATOM 1462 N N . VAL A 1 202 ? -11.706 0.244 33.072 1.00 27.65 ? 422 VAL A N 1 ATOM 1463 C CA . VAL A 1 202 ? -10.814 1.317 32.657 1.00 29.39 ? 422 VAL A CA 1 ATOM 1464 C C . VAL A 1 202 ? -10.771 1.350 31.137 1.00 31.15 ? 422 VAL A C 1 ATOM 1465 O O . VAL A 1 202 ? -10.544 0.326 30.491 1.00 35.96 ? 422 VAL A O 1 ATOM 1466 C CB . VAL A 1 202 ? -9.403 1.158 33.257 1.00 30.94 ? 422 VAL A CB 1 ATOM 1467 C CG1 . VAL A 1 202 ? -8.480 2.270 32.765 1.00 26.24 ? 422 VAL A CG1 1 ATOM 1468 C CG2 . VAL A 1 202 ? -9.483 1.170 34.789 1.00 29.17 ? 422 VAL A CG2 1 ATOM 1469 N N . PHE A 1 203 ? -11.028 2.528 30.578 1.00 32.11 ? 423 PHE A N 1 ATOM 1470 C CA . PHE A 1 203 ? -11.004 2.702 29.129 1.00 35.88 ? 423 PHE A CA 1 ATOM 1471 C C . PHE A 1 203 ? -9.866 3.638 28.752 1.00 34.13 ? 423 PHE A C 1 ATOM 1472 O O . PHE A 1 203 ? -9.609 4.653 29.423 1.00 30.76 ? 423 PHE A O 1 ATOM 1473 C CB . PHE A 1 203 ? -12.349 3.222 28.610 1.00 32.13 ? 423 PHE A CB 1 ATOM 1474 C CG . PHE A 1 203 ? -13.507 2.301 28.896 1.00 30.30 ? 423 PHE A CG 1 ATOM 1475 C CD1 . PHE A 1 203 ? -14.186 2.364 30.114 1.00 26.42 ? 423 PHE A CD1 1 ATOM 1476 C CD2 . PHE A 1 203 ? -13.920 1.369 27.955 1.00 24.12 ? 423 PHE A CD2 1 ATOM 1477 C CE1 . PHE A 1 203 ? -15.259 1.519 30.369 1.00 28.07 ? 423 PHE A CE1 1 ATOM 1478 C CE2 . PHE A 1 203 ? -14.980 0.521 28.209 1.00 24.24 ? 423 PHE A CE2 1 ATOM 1479 C CZ . PHE A 1 203 ? -15.657 0.595 29.415 1.00 29.70 ? 423 PHE A CZ 1 ATOM 1480 N N . SER A 1 204 ? -9.180 3.279 27.677 1.00 31.86 ? 424 SER A N 1 ATOM 1481 C CA . SER A 1 204 ? -7.998 4.006 27.261 1.00 34.93 ? 424 SER A CA 1 ATOM 1482 C C . SER A 1 204 ? -8.083 4.521 25.831 1.00 33.07 ? 424 SER A C 1 ATOM 1483 O O . SER A 1 204 ? -8.468 3.795 24.904 1.00 32.76 ? 424 SER A O 1 ATOM 1484 C CB . SER A 1 204 ? -6.748 3.154 27.472 1.00 33.09 ? 424 SER A CB 1 ATOM 1485 O OG . SER A 1 204 ? -6.291 3.280 28.810 1.00 41.84 ? 424 SER A OG 1 ATOM 1486 N N . CYS A 1 205 ? -7.729 5.794 25.691 1.00 33.53 ? 425 CYS A N 1 ATOM 1487 C CA . CYS A 1 205 ? -7.638 6.469 24.414 1.00 37.60 ? 425 CYS A CA 1 ATOM 1488 C C . CYS A 1 205 ? -6.174 6.515 24.014 1.00 35.58 ? 425 CYS A C 1 ATOM 1489 O O . CYS A 1 205 ? -5.343 7.028 24.762 1.00 38.24 ? 425 CYS A O 1 ATOM 1490 C CB . CYS A 1 205 ? -8.171 7.900 24.535 1.00 41.49 ? 425 CYS A CB 1 ATOM 1491 S SG . CYS A 1 205 ? -8.013 8.820 22.998 1.00 45.32 ? 425 CYS A SG 1 ATOM 1492 N N . SER A 1 206 ? -5.871 5.976 22.837 1.00 30.70 ? 426 SER A N 1 ATOM 1493 C CA . SER A 1 206 ? -4.501 5.897 22.335 1.00 35.04 ? 426 SER A CA 1 ATOM 1494 C C . SER A 1 206 ? -4.294 6.841 21.163 1.00 34.51 ? 426 SER A C 1 ATOM 1495 O O . SER A 1 206 ? -5.028 6.785 20.165 1.00 35.35 ? 426 SER A O 1 ATOM 1496 C CB . SER A 1 206 ? -4.172 4.464 21.904 1.00 33.13 ? 426 SER A CB 1 ATOM 1497 O OG . SER A 1 206 ? -4.396 3.555 22.969 1.00 46.91 ? 426 SER A OG 1 ATOM 1498 N N . VAL A 1 207 ? -3.289 7.700 21.273 1.00 35.53 ? 427 VAL A N 1 ATOM 1499 C CA . VAL A 1 207 ? -3.005 8.653 20.201 1.00 38.97 ? 427 VAL A CA 1 ATOM 1500 C C . VAL A 1 207 ? -1.597 8.438 19.656 1.00 37.21 ? 427 VAL A C 1 ATOM 1501 O O . VAL A 1 207 ? -0.620 8.426 20.413 1.00 35.39 ? 427 VAL A O 1 ATOM 1502 C CB . VAL A 1 207 ? -3.176 10.124 20.659 1.00 38.93 ? 427 VAL A CB 1 ATOM 1503 C CG1 . VAL A 1 207 ? -3.208 11.062 19.461 1.00 39.62 ? 427 VAL A CG1 1 ATOM 1504 C CG2 . VAL A 1 207 ? -4.455 10.292 21.465 1.00 41.23 ? 427 VAL A CG2 1 ATOM 1505 N N . MET A 1 208 ? -1.511 8.260 18.340 1.00 32.06 ? 428 MET A N 1 ATOM 1506 C CA . MET A 1 208 ? -0.232 8.190 17.639 1.00 35.31 ? 428 MET A CA 1 ATOM 1507 C C . MET A 1 208 ? -0.035 9.407 16.751 1.00 38.76 ? 428 MET A C 1 ATOM 1508 O O . MET A 1 208 ? -0.817 9.640 15.826 1.00 33.60 ? 428 MET A O 1 ATOM 1509 C CB . MET A 1 208 ? -0.130 6.924 16.793 1.00 36.35 ? 428 MET A CB 1 ATOM 1510 C CG . MET A 1 208 ? 0.027 5.661 17.614 1.00 43.35 ? 428 MET A CG 1 ATOM 1511 S SD . MET A 1 208 ? 0.173 4.227 16.546 1.00 55.70 ? 428 MET A SD 1 ATOM 1512 C CE . MET A 1 208 ? -1.021 3.144 17.311 1.00 62.67 ? 428 MET A CE 1 ATOM 1513 N N . HIS A 1 209 ? 1.025 10.161 17.041 1.00 35.35 ? 429 HIS A N 1 ATOM 1514 C CA . HIS A 1 209 ? 1.352 11.383 16.325 1.00 36.74 ? 429 HIS A CA 1 ATOM 1515 C C . HIS A 1 209 ? 2.847 11.621 16.346 1.00 41.49 ? 429 HIS A C 1 ATOM 1516 O O . HIS A 1 209 ? 3.504 11.429 17.380 1.00 30.63 ? 429 HIS A O 1 ATOM 1517 C CB . HIS A 1 209 ? 0.609 12.556 16.944 1.00 37.83 ? 429 HIS A CB 1 ATOM 1518 C CG . HIS A 1 209 ? 0.779 13.839 16.191 1.00 35.88 ? 429 HIS A CG 1 ATOM 1519 N ND1 . HIS A 1 209 ? 1.801 14.691 16.429 1.00 39.21 ? 429 HIS A ND1 1 ATOM 1520 C CD2 . HIS A 1 209 ? 0.031 14.397 15.165 1.00 26.86 ? 429 HIS A CD2 1 ATOM 1521 C CE1 . HIS A 1 209 ? 1.705 15.743 15.600 1.00 26.97 ? 429 HIS A CE1 1 ATOM 1522 N NE2 . HIS A 1 209 ? 0.623 15.560 14.823 1.00 25.50 ? 429 HIS A NE2 1 ATOM 1523 N N . GLU A 1 210 ? 3.400 12.055 15.212 1.00 40.58 ? 430 GLU A N 1 ATOM 1524 C CA . GLU A 1 210 ? 4.867 12.156 15.051 1.00 39.52 ? 430 GLU A CA 1 ATOM 1525 C C . GLU A 1 210 ? 5.576 12.955 16.134 1.00 40.61 ? 430 GLU A C 1 ATOM 1526 O O . GLU A 1 210 ? 6.710 12.640 16.493 1.00 43.65 ? 430 GLU A O 1 ATOM 1527 C CB . GLU A 1 210 ? 5.252 12.688 13.667 1.00 43.81 ? 430 GLU A CB 1 ATOM 1528 C CG . GLU A 1 210 ? 4.992 14.168 13.448 1.00 46.08 ? 430 GLU A CG 1 ATOM 1529 C CD . GLU A 1 210 ? 5.301 14.599 12.031 1.00 60.15 ? 430 GLU A CD 1 ATOM 1530 O OE1 . GLU A 1 210 ? 4.578 14.163 11.102 1.00 58.81 ? 430 GLU A OE1 1 ATOM 1531 O OE2 . GLU A 1 210 ? 6.267 15.376 11.855 1.00 65.74 ? 430 GLU A OE2 1 ATOM 1532 N N . ALA A 1 211 ? 4.899 13.975 16.652 1.00 34.14 ? 431 ALA A N 1 ATOM 1533 C CA . ALA A 1 211 ? 5.487 14.894 17.619 1.00 29.06 ? 431 ALA A CA 1 ATOM 1534 C C . ALA A 1 211 ? 5.332 14.448 19.082 1.00 30.11 ? 431 ALA A C 1 ATOM 1535 O O . ALA A 1 211 ? 5.774 15.141 19.998 1.00 36.87 ? 431 ALA A O 1 ATOM 1536 C CB . ALA A 1 211 ? 4.913 16.292 17.415 1.00 30.06 ? 431 ALA A CB 1 ATOM 1537 N N . LEU A 1 212 ? 4.700 13.301 19.301 1.00 32.96 ? 432 LEU A N 1 ATOM 1538 C CA . LEU A 1 212 ? 4.669 12.700 20.635 1.00 38.08 ? 432 LEU A CA 1 ATOM 1539 C C . LEU A 1 212 ? 5.952 11.931 20.873 1.00 38.15 ? 432 LEU A C 1 ATOM 1540 O O . LEU A 1 212 ? 6.537 11.379 19.929 1.00 35.60 ? 432 LEU A O 1 ATOM 1541 C CB . LEU A 1 212 ? 3.478 11.747 20.786 1.00 33.47 ? 432 LEU A CB 1 ATOM 1542 C CG . LEU A 1 212 ? 2.067 12.345 20.785 1.00 38.48 ? 432 LEU A CG 1 ATOM 1543 C CD1 . LEU A 1 212 ? 1.010 11.279 20.510 1.00 30.77 ? 432 LEU A CD1 1 ATOM 1544 C CD2 . LEU A 1 212 ? 1.798 13.069 22.090 1.00 31.12 ? 432 LEU A CD2 1 ATOM 1545 N N . HIS A 1 213 ? 6.386 11.896 22.132 1.00 35.34 ? 433 HIS A N 1 ATOM 1546 C CA . HIS A 1 213 ? 7.487 11.029 22.542 1.00 37.85 ? 433 HIS A CA 1 ATOM 1547 C C . HIS A 1 213 ? 7.192 9.627 22.098 1.00 30.63 ? 433 HIS A C 1 ATOM 1548 O O . HIS A 1 213 ? 6.127 9.083 22.397 1.00 30.03 ? 433 HIS A O 1 ATOM 1549 C CB . HIS A 1 213 ? 7.701 11.087 24.055 1.00 35.65 ? 433 HIS A CB 1 ATOM 1550 C CG . HIS A 1 213 ? 8.881 10.282 24.527 1.00 43.94 ? 433 HIS A CG 1 ATOM 1551 N ND1 . HIS A 1 213 ? 10.158 10.670 24.313 1.00 48.52 ? 433 HIS A ND1 1 ATOM 1552 C CD2 . HIS A 1 213 ? 8.947 9.066 25.210 1.00 42.63 ? 433 HIS A CD2 1 ATOM 1553 C CE1 . HIS A 1 213 ? 10.996 9.757 24.840 1.00 43.43 ? 433 HIS A CE1 1 ATOM 1554 N NE2 . HIS A 1 213 ? 10.252 8.775 25.388 1.00 42.38 ? 433 HIS A NE2 1 ATOM 1555 N N . ASN A 1 214 ? 8.121 9.043 21.348 1.00 34.72 ? 434 ASN A N 1 ATOM 1556 C CA . ASN A 1 214 ? 7.917 7.732 20.713 1.00 36.15 ? 434 ASN A CA 1 ATOM 1557 C C . ASN A 1 214 ? 6.619 7.570 19.879 1.00 36.78 ? 434 ASN A C 1 ATOM 1558 O O . ASN A 1 214 ? 6.101 6.457 19.717 1.00 33.49 ? 434 ASN A O 1 ATOM 1559 C CB . ASN A 1 214 ? 8.101 6.605 21.746 1.00 34.66 ? 434 ASN A CB 1 ATOM 1560 C CG . ASN A 1 214 ? 9.568 6.360 22.077 1.00 44.34 ? 434 ASN A CG 1 ATOM 1561 O OD1 . ASN A 1 214 ? 10.465 6.685 21.280 1.00 39.48 ? 434 ASN A OD1 1 ATOM 1562 N ND2 . ASN A 1 214 ? 9.823 5.789 23.250 1.00 41.86 ? 434 ASN A ND2 1 ATOM 1563 N N . HIS A 1 215 ? 6.124 8.689 19.346 1.00 32.23 ? 435 HIS A N 1 ATOM 1564 C CA . HIS A 1 215 ? 4.927 8.746 18.492 1.00 29.67 ? 435 HIS A CA 1 ATOM 1565 C C . HIS A 1 215 ? 3.663 8.272 19.173 1.00 35.82 ? 435 HIS A C 1 ATOM 1566 O O . HIS A 1 215 ? 2.720 7.854 18.495 1.00 25.34 ? 435 HIS A O 1 ATOM 1567 C CB . HIS A 1 215 ? 5.108 7.953 17.200 1.00 35.99 ? 435 HIS A CB 1 ATOM 1568 C CG . HIS A 1 215 ? 6.248 8.418 16.317 1.00 39.48 ? 435 HIS A CG 1 ATOM 1569 N ND1 . HIS A 1 215 ? 6.733 7.655 15.318 1.00 32.88 ? 435 HIS A ND1 1 ATOM 1570 C CD2 . HIS A 1 215 ? 6.990 9.597 16.302 1.00 38.09 ? 435 HIS A CD2 1 ATOM 1571 C CE1 . HIS A 1 215 ? 7.731 8.307 14.694 1.00 33.27 ? 435 HIS A CE1 1 ATOM 1572 N NE2 . HIS A 1 215 ? 7.888 9.496 15.292 1.00 34.33 ? 435 HIS A NE2 1 ATOM 1573 N N . TYR A 1 216 ? 3.612 8.328 20.506 1.00 27.72 ? 436 TYR A N 1 ATOM 1574 C CA . TYR A 1 216 ? 2.570 7.615 21.226 1.00 27.29 ? 436 TYR A CA 1 ATOM 1575 C C . TYR A 1 216 ? 2.313 8.210 22.570 1.00 35.48 ? 436 TYR A C 1 ATOM 1576 O O . TYR A 1 216 ? 3.258 8.567 23.277 1.00 28.80 ? 436 TYR A O 1 ATOM 1577 C CB . TYR A 1 216 ? 2.993 6.176 21.464 1.00 28.06 ? 436 TYR A CB 1 ATOM 1578 C CG . TYR A 1 216 ? 1.883 5.230 21.880 1.00 30.24 ? 436 TYR A CG 1 ATOM 1579 C CD1 . TYR A 1 216 ? 1.729 4.844 23.206 1.00 30.85 ? 436 TYR A CD1 1 ATOM 1580 C CD2 . TYR A 1 216 ? 1.019 4.680 20.929 1.00 32.12 ? 436 TYR A CD2 1 ATOM 1581 C CE1 . TYR A 1 216 ? 0.726 3.954 23.582 1.00 36.43 ? 436 TYR A CE1 1 ATOM 1582 C CE2 . TYR A 1 216 ? 0.015 3.796 21.293 1.00 34.91 ? 436 TYR A CE2 1 ATOM 1583 C CZ . TYR A 1 216 ? -0.129 3.433 22.619 1.00 41.83 ? 436 TYR A CZ 1 ATOM 1584 O OH . TYR A 1 216 ? -1.130 2.544 22.978 1.00 52.51 ? 436 TYR A OH 1 ATOM 1585 N N . THR A 1 217 ? 1.023 8.296 22.904 1.00 39.58 ? 437 THR A N 1 ATOM 1586 C CA . THR A 1 217 ? 0.563 8.574 24.259 1.00 41.32 ? 437 THR A CA 1 ATOM 1587 C C . THR A 1 217 ? -0.779 7.882 24.525 1.00 39.69 ? 437 THR A C 1 ATOM 1588 O O . THR A 1 217 ? -1.562 7.620 23.602 1.00 38.70 ? 437 THR A O 1 ATOM 1589 C CB . THR A 1 217 ? 0.479 10.085 24.559 1.00 44.33 ? 437 THR A CB 1 ATOM 1590 O OG1 . THR A 1 217 ? 0.317 10.280 25.970 1.00 45.94 ? 437 THR A OG1 1 ATOM 1591 C CG2 . THR A 1 217 ? -0.687 10.729 23.818 1.00 45.05 ? 437 THR A CG2 1 ATOM 1592 N N . GLN A 1 218 ? -1.021 7.573 25.793 1.00 33.42 ? 438 GLN A N 1 ATOM 1593 C CA . GLN A 1 218 ? -2.227 6.882 26.213 1.00 33.21 ? 438 GLN A CA 1 ATOM 1594 C C . GLN A 1 218 ? -2.833 7.608 27.396 1.00 40.34 ? 438 GLN A C 1 ATOM 1595 O O . GLN A 1 218 ? -2.114 8.054 28.297 1.00 36.28 ? 438 GLN A O 1 ATOM 1596 C CB . GLN A 1 218 ? -1.902 5.440 26.593 1.00 32.78 ? 438 GLN A CB 1 ATOM 1597 C CG . GLN A 1 218 ? -3.100 4.511 26.629 1.00 42.56 ? 438 GLN A CG 1 ATOM 1598 C CD . GLN A 1 218 ? -2.695 3.047 26.590 1.00 53.92 ? 438 GLN A CD 1 ATOM 1599 O OE1 . GLN A 1 218 ? -3.023 2.325 25.646 1.00 56.99 ? 438 GLN A OE1 1 ATOM 1600 N NE2 . GLN A 1 218 ? -1.969 2.605 27.611 1.00 67.08 ? 438 GLN A NE2 1 ATOM 1601 N N . LYS A 1 219 ? -4.154 7.749 27.380 1.00 39.61 ? 439 LYS A N 1 ATOM 1602 C CA . LYS A 1 219 ? -4.859 8.350 28.499 1.00 40.11 ? 439 LYS A CA 1 ATOM 1603 C C . LYS A 1 219 ? -6.015 7.455 28.900 1.00 41.22 ? 439 LYS A C 1 ATOM 1604 O O . LYS A 1 219 ? -6.713 6.895 28.045 1.00 41.67 ? 439 LYS A O 1 ATOM 1605 C CB . LYS A 1 219 ? -5.354 9.757 28.156 1.00 41.10 ? 439 LYS A CB 1 ATOM 1606 C CG . LYS A 1 219 ? -4.275 10.725 27.692 1.00 46.66 ? 439 LYS A CG 1 ATOM 1607 C CD . LYS A 1 219 ? -3.464 11.325 28.834 1.00 46.90 ? 439 LYS A CD 1 ATOM 1608 C CE . LYS A 1 219 ? -2.297 12.127 28.270 1.00 52.12 ? 439 LYS A CE 1 ATOM 1609 N NZ . LYS A 1 219 ? -1.606 12.964 29.289 1.00 59.68 ? 439 LYS A NZ 1 ATOM 1610 N N . SER A 1 220 ? -6.194 7.321 30.210 1.00 43.65 ? 440 SER A N 1 ATOM 1611 C CA . SER A 1 220 ? -7.186 6.424 30.781 1.00 37.33 ? 440 SER A CA 1 ATOM 1612 C C . SER A 1 220 ? -8.283 7.147 31.555 1.00 37.88 ? 440 SER A C 1 ATOM 1613 O O . SER A 1 220 ? -8.114 8.285 32.000 1.00 33.85 ? 440 SER A O 1 ATOM 1614 C CB . SER A 1 220 ? -6.512 5.360 31.643 1.00 37.27 ? 440 SER A CB 1 ATOM 1615 O OG . SER A 1 220 ? -5.929 4.363 30.819 1.00 38.23 ? 440 SER A OG 1 ATOM 1616 N N . LEU A 1 221 ? -9.408 6.456 31.704 1.00 36.16 ? 441 LEU A N 1 ATOM 1617 C CA . LEU A 1 221 ? -10.645 7.040 32.179 1.00 37.42 ? 441 LEU A CA 1 ATOM 1618 C C . LEU A 1 221 ? -11.460 5.918 32.809 1.00 35.91 ? 441 LEU A C 1 ATOM 1619 O O . LEU A 1 221 ? -11.649 4.867 32.195 1.00 32.22 ? 441 LEU A O 1 ATOM 1620 C CB . LEU A 1 221 ? -11.398 7.638 30.978 1.00 43.77 ? 441 LEU A CB 1 ATOM 1621 C CG . LEU A 1 221 ? -12.710 8.402 31.131 1.00 49.91 ? 441 LEU A CG 1 ATOM 1622 C CD1 . LEU A 1 221 ? -12.530 9.678 31.940 1.00 53.61 ? 441 LEU A CD1 1 ATOM 1623 C CD2 . LEU A 1 221 ? -13.269 8.722 29.758 1.00 53.79 ? 441 LEU A CD2 1 ATOM 1624 N N . SER A 1 222 ? -11.914 6.128 34.043 1.00 39.69 ? 442 SER A N 1 ATOM 1625 C CA . SER A 1 222 ? -12.842 5.194 34.685 1.00 37.18 ? 442 SER A CA 1 ATOM 1626 C C . SER A 1 222 ? -13.723 5.917 35.704 1.00 33.84 ? 442 SER A C 1 ATOM 1627 O O . SER A 1 222 ? -13.435 7.055 36.069 1.00 34.65 ? 442 SER A O 1 ATOM 1628 C CB . SER A 1 222 ? -12.106 4.000 35.301 1.00 36.62 ? 442 SER A CB 1 ATOM 1629 O OG . SER A 1 222 ? -11.376 4.378 36.454 1.00 45.72 ? 442 SER A OG 1 ATOM 1630 N N . LEU A 1 223 ? -14.807 5.263 36.125 1.00 35.66 ? 443 LEU A N 1 ATOM 1631 C CA . LEU A 1 223 ? -15.791 5.824 37.069 1.00 39.70 ? 443 LEU A CA 1 ATOM 1632 C C . LEU A 1 223 ? -15.153 6.533 38.274 1.00 35.85 ? 443 LEU A C 1 ATOM 1633 O O . LEU A 1 223 ? -14.151 6.065 38.813 1.00 32.92 ? 443 LEU A O 1 ATOM 1634 C CB . LEU A 1 223 ? -16.732 4.712 37.546 1.00 39.21 ? 443 LEU A CB 1 ATOM 1635 C CG . LEU A 1 223 ? -17.840 5.011 38.563 1.00 47.71 ? 443 LEU A CG 1 ATOM 1636 C CD1 . LEU A 1 223 ? -19.002 5.741 37.910 1.00 47.17 ? 443 LEU A CD1 1 ATOM 1637 C CD2 . LEU A 1 223 ? -18.319 3.727 39.235 1.00 41.27 ? 443 LEU A CD2 1 ATOM 1638 N N . GLY B 2 30 ? -22.378 23.576 -23.554 1.00 56.73 ? 237 GLY B N 1 ATOM 1639 C CA . GLY B 2 30 ? -23.622 23.822 -22.767 1.00 62.23 ? 237 GLY B CA 1 ATOM 1640 C C . GLY B 2 30 ? -23.378 24.212 -21.316 1.00 60.16 ? 237 GLY B C 1 ATOM 1641 O O . GLY B 2 30 ? -22.410 23.757 -20.700 1.00 59.96 ? 237 GLY B O 1 ATOM 1642 N N . PRO B 2 31 ? -24.254 25.068 -20.762 1.00 56.22 ? 238 PRO B N 1 ATOM 1643 C CA . PRO B 2 31 ? -24.207 25.493 -19.354 1.00 53.40 ? 238 PRO B CA 1 ATOM 1644 C C . PRO B 2 31 ? -24.448 24.353 -18.362 1.00 49.78 ? 238 PRO B C 1 ATOM 1645 O O . PRO B 2 31 ? -24.941 23.297 -18.756 1.00 44.95 ? 238 PRO B O 1 ATOM 1646 C CB . PRO B 2 31 ? -25.340 26.526 -19.260 1.00 56.30 ? 238 PRO B CB 1 ATOM 1647 C CG . PRO B 2 31 ? -26.196 26.301 -20.465 1.00 56.27 ? 238 PRO B CG 1 ATOM 1648 C CD . PRO B 2 31 ? -25.258 25.827 -21.528 1.00 55.32 ? 238 PRO B CD 1 ATOM 1649 N N . SER B 2 32 ? -24.104 24.576 -17.090 1.00 52.44 ? 239 SER B N 1 ATOM 1650 C CA . SER B 2 32 ? -24.288 23.576 -16.026 1.00 51.21 ? 239 SER B CA 1 ATOM 1651 C C . SER B 2 32 ? -25.015 24.115 -14.792 1.00 57.05 ? 239 SER B C 1 ATOM 1652 O O . SER B 2 32 ? -24.763 25.246 -14.356 1.00 54.39 ? 239 SER B O 1 ATOM 1653 C CB . SER B 2 32 ? -22.944 22.985 -15.603 1.00 49.54 ? 239 SER B CB 1 ATOM 1654 O OG . SER B 2 32 ? -22.441 22.130 -16.611 1.00 66.63 ? 239 SER B OG 1 ATOM 1655 N N . VAL B 2 33 ? -25.884 23.279 -14.218 1.00 47.58 ? 240 VAL B N 1 ATOM 1656 C CA . VAL B 2 33 ? -26.782 23.676 -13.126 1.00 42.51 ? 240 VAL B CA 1 ATOM 1657 C C . VAL B 2 33 ? -26.402 23.052 -11.785 1.00 40.52 ? 240 VAL B C 1 ATOM 1658 O O . VAL B 2 33 ? -26.123 21.861 -11.700 1.00 41.66 ? 240 VAL B O 1 ATOM 1659 C CB . VAL B 2 33 ? -28.247 23.280 -13.436 1.00 43.08 ? 240 VAL B CB 1 ATOM 1660 C CG1 . VAL B 2 33 ? -29.198 23.842 -12.383 1.00 36.73 ? 240 VAL B CG1 1 ATOM 1661 C CG2 . VAL B 2 33 ? -28.655 23.740 -14.831 1.00 37.13 ? 240 VAL B CG2 1 ATOM 1662 N N . PHE B 2 34 ? -26.419 23.867 -10.740 1.00 46.35 ? 241 PHE B N 1 ATOM 1663 C CA . PHE B 2 34 ? -26.225 23.388 -9.379 1.00 46.24 ? 241 PHE B CA 1 ATOM 1664 C C . PHE B 2 34 ? -27.314 23.964 -8.487 1.00 44.73 ? 241 PHE B C 1 ATOM 1665 O O . PHE B 2 34 ? -27.589 25.168 -8.526 1.00 38.93 ? 241 PHE B O 1 ATOM 1666 C CB . PHE B 2 34 ? -24.827 23.754 -8.869 1.00 50.73 ? 241 PHE B CB 1 ATOM 1667 C CG . PHE B 2 34 ? -23.716 23.217 -9.732 1.00 58.39 ? 241 PHE B CG 1 ATOM 1668 C CD1 . PHE B 2 34 ? -23.331 21.878 -9.647 1.00 64.03 ? 241 PHE B CD1 1 ATOM 1669 C CD2 . PHE B 2 34 ? -23.068 24.040 -10.649 1.00 58.95 ? 241 PHE B CD2 1 ATOM 1670 C CE1 . PHE B 2 34 ? -22.321 21.375 -10.455 1.00 59.79 ? 241 PHE B CE1 1 ATOM 1671 C CE2 . PHE B 2 34 ? -22.052 23.544 -11.456 1.00 62.08 ? 241 PHE B CE2 1 ATOM 1672 C CZ . PHE B 2 34 ? -21.680 22.208 -11.359 1.00 65.17 ? 241 PHE B CZ 1 ATOM 1673 N N . LEU B 2 35 ? -27.940 23.092 -7.698 1.00 45.26 ? 242 LEU B N 1 ATOM 1674 C CA . LEU B 2 35 ? -29.051 23.482 -6.840 1.00 36.85 ? 242 LEU B CA 1 ATOM 1675 C C . LEU B 2 35 ? -28.719 23.367 -5.362 1.00 43.06 ? 242 LEU B C 1 ATOM 1676 O O . LEU B 2 35 ? -28.432 22.284 -4.857 1.00 55.74 ? 242 LEU B O 1 ATOM 1677 C CB . LEU B 2 35 ? -30.290 22.660 -7.167 1.00 37.87 ? 242 LEU B CB 1 ATOM 1678 C CG . LEU B 2 35 ? -31.600 23.059 -6.484 1.00 41.42 ? 242 LEU B CG 1 ATOM 1679 C CD1 . LEU B 2 35 ? -31.847 24.566 -6.503 1.00 37.12 ? 242 LEU B CD1 1 ATOM 1680 C CD2 . LEU B 2 35 ? -32.755 22.305 -7.125 1.00 42.10 ? 242 LEU B CD2 1 ATOM 1681 N N . PHE B 2 36 ? -28.805 24.497 -4.674 1.00 44.71 ? 243 PHE B N 1 ATOM 1682 C CA . PHE B 2 36 ? -28.379 24.608 -3.289 1.00 44.80 ? 243 PHE B CA 1 ATOM 1683 C C . PHE B 2 36 ? -29.553 24.816 -2.329 1.00 50.80 ? 243 PHE B C 1 ATOM 1684 O O . PHE B 2 36 ? -30.552 25.451 -2.691 1.00 47.90 ? 243 PHE B O 1 ATOM 1685 C CB . PHE B 2 36 ? -27.362 25.751 -3.147 1.00 46.12 ? 243 PHE B CB 1 ATOM 1686 C CG . PHE B 2 36 ? -26.163 25.608 -4.040 1.00 40.37 ? 243 PHE B CG 1 ATOM 1687 C CD1 . PHE B 2 36 ? -25.130 24.742 -3.705 1.00 49.57 ? 243 PHE B CD1 1 ATOM 1688 C CD2 . PHE B 2 36 ? -26.070 26.330 -5.219 1.00 47.58 ? 243 PHE B CD2 1 ATOM 1689 C CE1 . PHE B 2 36 ? -24.021 24.605 -4.529 1.00 51.53 ? 243 PHE B CE1 1 ATOM 1690 C CE2 . PHE B 2 36 ? -24.964 26.198 -6.051 1.00 57.72 ? 243 PHE B CE2 1 ATOM 1691 C CZ . PHE B 2 36 ? -23.937 25.334 -5.704 1.00 56.22 ? 243 PHE B CZ 1 ATOM 1692 N N . PRO B 2 37 ? -29.438 24.271 -1.101 1.00 46.00 ? 244 PRO B N 1 ATOM 1693 C CA . PRO B 2 37 ? -30.477 24.416 -0.078 1.00 40.50 ? 244 PRO B CA 1 ATOM 1694 C C . PRO B 2 37 ? -30.351 25.705 0.729 1.00 40.23 ? 244 PRO B C 1 ATOM 1695 O O . PRO B 2 37 ? -29.360 26.417 0.594 1.00 44.03 ? 244 PRO B O 1 ATOM 1696 C CB . PRO B 2 37 ? -30.247 23.196 0.818 1.00 33.47 ? 244 PRO B CB 1 ATOM 1697 C CG . PRO B 2 37 ? -28.787 22.930 0.715 1.00 39.65 ? 244 PRO B CG 1 ATOM 1698 C CD . PRO B 2 37 ? -28.366 23.351 -0.670 1.00 41.14 ? 244 PRO B CD 1 ATOM 1699 N N . PRO B 2 38 ? -31.361 26.019 1.555 1.00 43.96 ? 245 PRO B N 1 ATOM 1700 C CA . PRO B 2 38 ? -31.232 27.140 2.490 1.00 46.25 ? 245 PRO B CA 1 ATOM 1701 C C . PRO B 2 38 ? -30.221 26.861 3.602 1.00 50.37 ? 245 PRO B C 1 ATOM 1702 O O . PRO B 2 38 ? -29.806 25.719 3.786 1.00 50.18 ? 245 PRO B O 1 ATOM 1703 C CB . PRO B 2 38 ? -32.641 27.264 3.083 1.00 41.21 ? 245 PRO B CB 1 ATOM 1704 C CG . PRO B 2 38 ? -33.264 25.924 2.874 1.00 43.44 ? 245 PRO B CG 1 ATOM 1705 C CD . PRO B 2 38 ? -32.726 25.461 1.556 1.00 40.34 ? 245 PRO B CD 1 ATOM 1706 N N . LYS B 2 39 ? -29.832 27.906 4.326 1.00 50.30 ? 246 LYS B N 1 ATOM 1707 C CA . LYS B 2 39 ? -28.959 27.766 5.483 1.00 55.33 ? 246 LYS B CA 1 ATOM 1708 C C . LYS B 2 39 ? -29.750 27.245 6.672 1.00 46.76 ? 246 LYS B C 1 ATOM 1709 O O . LYS B 2 39 ? -30.797 27.793 7.000 1.00 50.35 ? 246 LYS B O 1 ATOM 1710 C CB . LYS B 2 39 ? -28.301 29.106 5.841 1.00 60.47 ? 246 LYS B CB 1 ATOM 1711 C CG . LYS B 2 39 ? -27.160 29.522 4.928 1.00 62.92 ? 246 LYS B CG 1 ATOM 1712 C CD . LYS B 2 39 ? -25.969 28.574 5.019 1.00 68.37 ? 246 LYS B CD 1 ATOM 1713 C CE . LYS B 2 39 ? -24.960 28.839 3.911 1.00 67.92 ? 246 LYS B CE 1 ATOM 1714 N NZ . LYS B 2 39 ? -25.562 28.739 2.548 1.00 59.49 ? 246 LYS B NZ 1 ATOM 1715 N N . PRO B 2 40 ? -29.252 26.183 7.324 1.00 52.86 ? 247 PRO B N 1 ATOM 1716 C CA . PRO B 2 40 ? -29.923 25.589 8.482 1.00 51.37 ? 247 PRO B CA 1 ATOM 1717 C C . PRO B 2 40 ? -30.458 26.629 9.466 1.00 49.36 ? 247 PRO B C 1 ATOM 1718 O O . PRO B 2 40 ? -31.602 26.527 9.920 1.00 50.49 ? 247 PRO B O 1 ATOM 1719 C CB . PRO B 2 40 ? -28.815 24.754 9.122 1.00 57.74 ? 247 PRO B CB 1 ATOM 1720 C CG . PRO B 2 40 ? -27.992 24.306 7.959 1.00 56.84 ? 247 PRO B CG 1 ATOM 1721 C CD . PRO B 2 40 ? -28.060 25.407 6.927 1.00 53.78 ? 247 PRO B CD 1 ATOM 1722 N N . LYS B 2 41 ? -29.647 27.633 9.770 1.00 42.47 ? 248 LYS B N 1 ATOM 1723 C CA . LYS B 2 41 ? -30.068 28.716 10.649 1.00 51.66 ? 248 LYS B CA 1 ATOM 1724 C C . LYS B 2 41 ? -31.326 29.447 10.124 1.00 52.16 ? 248 LYS B C 1 ATOM 1725 O O . LYS B 2 41 ? -32.225 29.772 10.903 1.00 56.34 ? 248 LYS B O 1 ATOM 1726 C CB . LYS B 2 41 ? -28.905 29.688 10.874 1.00 57.37 ? 248 LYS B CB 1 ATOM 1727 C CG . LYS B 2 41 ? -28.974 30.440 12.194 1.00 67.07 ? 248 LYS B CG 1 ATOM 1728 C CD . LYS B 2 41 ? -27.629 31.037 12.582 1.00 63.33 ? 248 LYS B CD 1 ATOM 1729 C CE . LYS B 2 41 ? -27.740 31.823 13.879 1.00 60.29 ? 248 LYS B CE 1 ATOM 1730 N N . ASP B 2 42 ? -31.389 29.677 8.810 1.00 51.65 ? 249 ASP B N 1 ATOM 1731 C CA . ASP B 2 42 ? -32.512 30.381 8.177 1.00 46.41 ? 249 ASP B CA 1 ATOM 1732 C C . ASP B 2 42 ? -33.839 29.612 8.252 1.00 45.90 ? 249 ASP B C 1 ATOM 1733 O O . ASP B 2 42 ? -34.901 30.219 8.425 1.00 43.41 ? 249 ASP B O 1 ATOM 1734 C CB . ASP B 2 42 ? -32.186 30.740 6.717 1.00 45.47 ? 249 ASP B CB 1 ATOM 1735 C CG . ASP B 2 42 ? -31.023 31.735 6.585 1.00 56.12 ? 249 ASP B CG 1 ATOM 1736 O OD1 . ASP B 2 42 ? -30.585 32.328 7.600 1.00 50.47 ? 249 ASP B OD1 1 ATOM 1737 O OD2 . ASP B 2 42 ? -30.542 31.925 5.446 1.00 54.54 ? 249 ASP B OD2 1 ATOM 1738 N N . THR B 2 43 ? -33.779 28.285 8.125 1.00 42.06 ? 250 THR B N 1 ATOM 1739 C CA . THR B 2 43 ? -34.976 27.445 8.245 1.00 39.11 ? 250 THR B CA 1 ATOM 1740 C C . THR B 2 43 ? -35.486 27.357 9.684 1.00 44.86 ? 250 THR B C 1 ATOM 1741 O O . THR B 2 43 ? -36.646 27.027 9.910 1.00 45.72 ? 250 THR B O 1 ATOM 1742 C CB . THR B 2 43 ? -34.739 26.008 7.737 1.00 41.55 ? 250 THR B CB 1 ATOM 1743 O OG1 . THR B 2 43 ? -33.663 25.411 8.468 1.00 43.54 ? 250 THR B OG1 1 ATOM 1744 C CG2 . THR B 2 43 ? -34.397 25.986 6.254 1.00 41.22 ? 250 THR B CG2 1 ATOM 1745 N N . LEU B 2 44 ? -34.617 27.655 10.647 1.00 46.70 ? 251 LEU B N 1 ATOM 1746 C CA . LEU B 2 44 ? -34.900 27.386 12.064 1.00 52.30 ? 251 LEU B CA 1 ATOM 1747 C C . LEU B 2 44 ? -35.213 28.623 12.887 1.00 56.35 ? 251 LEU B C 1 ATOM 1748 O O . LEU B 2 44 ? -35.754 28.510 13.984 1.00 59.16 ? 251 LEU B O 1 ATOM 1749 C CB . LEU B 2 44 ? -33.726 26.645 12.719 1.00 54.19 ? 251 LEU B CB 1 ATOM 1750 C CG . LEU B 2 44 ? -33.265 25.299 12.161 1.00 56.57 ? 251 LEU B CG 1 ATOM 1751 C CD1 . LEU B 2 44 ? -32.016 24.825 12.887 1.00 64.60 ? 251 LEU B CD1 1 ATOM 1752 C CD2 . LEU B 2 44 ? -34.363 24.250 12.237 1.00 63.88 ? 251 LEU B CD2 1 ATOM 1753 N N . GLU B 2 45 ? -34.842 29.796 12.380 1.00 64.70 ? 252 GLU B N 1 ATOM 1754 C CA . GLU B 2 45 ? -35.161 31.054 13.054 1.00 68.06 ? 252 GLU B CA 1 ATOM 1755 C C . GLU B 2 45 ? -36.335 31.735 12.369 1.00 64.24 ? 252 GLU B C 1 ATOM 1756 O O . GLU B 2 45 ? -36.290 32.015 11.167 1.00 68.57 ? 252 GLU B O 1 ATOM 1757 C CB . GLU B 2 45 ? -33.947 31.989 13.113 1.00 73.57 ? 252 GLU B CB 1 ATOM 1758 C CG . GLU B 2 45 ? -33.158 31.899 14.414 1.00 77.64 ? 252 GLU B CG 1 ATOM 1759 C CD . GLU B 2 45 ? -32.264 33.108 14.663 1.00 86.25 ? 252 GLU B CD 1 ATOM 1760 O OE1 . GLU B 2 45 ? -32.192 33.565 15.824 1.00 87.87 ? 252 GLU B OE1 1 ATOM 1761 O OE2 . GLU B 2 45 ? -31.631 33.605 13.706 1.00 75.97 ? 252 GLU B OE2 1 ATOM 1762 N N . ALA B 2 46 ? -37.386 31.991 13.144 1.00 62.62 ? 253 ALA B N 1 ATOM 1763 C CA . ALA B 2 46 ? -38.614 32.591 12.627 1.00 74.65 ? 253 ALA B CA 1 ATOM 1764 C C . ALA B 2 46 ? -38.352 33.871 11.830 1.00 80.22 ? 253 ALA B C 1 ATOM 1765 O O . ALA B 2 46 ? -38.921 34.070 10.753 1.00 86.67 ? 253 ALA B O 1 ATOM 1766 C CB . ALA B 2 46 ? -39.583 32.865 13.768 1.00 81.23 ? 253 ALA B CB 1 ATOM 1767 N N . SER B 2 47 ? -37.465 34.711 12.356 1.00 66.98 ? 254 SER B N 1 ATOM 1768 C CA . SER B 2 47 ? -37.223 36.051 11.822 1.00 59.17 ? 254 SER B CA 1 ATOM 1769 C C . SER B 2 47 ? -36.364 36.123 10.552 1.00 50.98 ? 254 SER B C 1 ATOM 1770 O O . SER B 2 47 ? -36.220 37.201 9.976 1.00 44.66 ? 254 SER B O 1 ATOM 1771 C CB . SER B 2 47 ? -36.623 36.941 12.916 1.00 59.69 ? 254 SER B CB 1 ATOM 1772 O OG . SER B 2 47 ? -35.601 36.256 13.620 1.00 64.02 ? 254 SER B OG 1 ATOM 1773 N N . ARG B 2 48 ? -35.792 34.995 10.123 1.00 46.42 ? 255 ARG B N 1 ATOM 1774 C CA . ARG B 2 48 ? -34.963 34.967 8.910 1.00 41.68 ? 255 ARG B CA 1 ATOM 1775 C C . ARG B 2 48 ? -35.723 34.405 7.710 1.00 45.88 ? 255 ARG B C 1 ATOM 1776 O O . ARG B 2 48 ? -36.797 33.818 7.866 1.00 48.50 ? 255 ARG B O 1 ATOM 1777 C CB . ARG B 2 48 ? -33.659 34.197 9.138 1.00 41.15 ? 255 ARG B CB 1 ATOM 1778 C CG . ARG B 2 48 ? -32.633 34.973 9.945 1.00 54.41 ? 255 ARG B CG 1 ATOM 1779 C CD . ARG B 2 48 ? -31.267 34.313 9.921 1.00 59.97 ? 255 ARG B CD 1 ATOM 1780 N NE . ARG B 2 48 ? -30.656 34.316 11.249 1.00 75.11 ? 255 ARG B NE 1 ATOM 1781 C CZ . ARG B 2 48 ? -29.930 35.311 11.755 1.00 82.20 ? 255 ARG B CZ 1 ATOM 1782 N NH1 . ARG B 2 48 ? -29.702 36.413 11.047 1.00 95.26 ? 255 ARG B NH1 1 ATOM 1783 N NH2 . ARG B 2 48 ? -29.431 35.205 12.980 1.00 68.16 ? 255 ARG B NH2 1 ATOM 1784 N N . THR B 2 49 ? -35.147 34.573 6.521 1.00 43.16 ? 256 THR B N 1 ATOM 1785 C CA . THR B 2 49 ? -35.815 34.253 5.264 1.00 47.98 ? 256 THR B CA 1 ATOM 1786 C C . THR B 2 49 ? -35.043 33.177 4.489 1.00 43.91 ? 256 THR B C 1 ATOM 1787 O O . THR B 2 49 ? -34.107 33.494 3.757 1.00 43.02 ? 256 THR B O 1 ATOM 1788 C CB . THR B 2 49 ? -35.975 35.531 4.407 1.00 51.54 ? 256 THR B CB 1 ATOM 1789 O OG1 . THR B 2 49 ? -36.551 36.569 5.209 1.00 55.30 ? 256 THR B OG1 1 ATOM 1790 C CG2 . THR B 2 49 ? -36.867 35.290 3.210 1.00 50.43 ? 256 THR B CG2 1 ATOM 1791 N N . PRO B 2 50 ? -35.431 31.896 4.651 1.00 44.61 ? 257 PRO B N 1 ATOM 1792 C CA . PRO B 2 50 ? -34.750 30.819 3.931 1.00 38.64 ? 257 PRO B CA 1 ATOM 1793 C C . PRO B 2 50 ? -35.085 30.862 2.447 1.00 40.20 ? 257 PRO B C 1 ATOM 1794 O O . PRO B 2 50 ? -36.172 31.307 2.079 1.00 40.21 ? 257 PRO B O 1 ATOM 1795 C CB . PRO B 2 50 ? -35.335 29.550 4.554 1.00 42.37 ? 257 PRO B CB 1 ATOM 1796 C CG . PRO B 2 50 ? -36.672 29.957 5.058 1.00 48.92 ? 257 PRO B CG 1 ATOM 1797 C CD . PRO B 2 50 ? -36.528 31.386 5.496 1.00 46.00 ? 257 PRO B CD 1 ATOM 1798 N N . GLU B 2 51 ? -34.152 30.402 1.618 1.00 35.67 ? 258 GLU B N 1 ATOM 1799 C CA . GLU B 2 51 ? -34.309 30.396 0.170 1.00 38.72 ? 258 GLU B CA 1 ATOM 1800 C C . GLU B 2 51 ? -33.520 29.266 -0.494 1.00 43.58 ? 258 GLU B C 1 ATOM 1801 O O . GLU B 2 51 ? -32.496 28.803 0.026 1.00 45.98 ? 258 GLU B O 1 ATOM 1802 C CB . GLU B 2 51 ? -33.895 31.747 -0.420 1.00 44.89 ? 258 GLU B CB 1 ATOM 1803 C CG . GLU B 2 51 ? -32.466 32.147 -0.086 1.00 46.02 ? 258 GLU B CG 1 ATOM 1804 C CD . GLU B 2 51 ? -32.150 33.598 -0.380 1.00 47.10 ? 258 GLU B CD 1 ATOM 1805 O OE1 . GLU B 2 51 ? -31.015 33.862 -0.827 1.00 51.84 ? 258 GLU B OE1 1 ATOM 1806 O OE2 . GLU B 2 51 ? -33.019 34.471 -0.163 1.00 48.45 ? 258 GLU B OE2 1 ATOM 1807 N N . VAL B 2 52 ? -34.011 28.832 -1.651 1.00 41.82 ? 259 VAL B N 1 ATOM 1808 C CA . VAL B 2 52 ? -33.367 27.790 -2.435 1.00 37.67 ? 259 VAL B CA 1 ATOM 1809 C C . VAL B 2 52 ? -32.750 28.448 -3.659 1.00 34.89 ? 259 VAL B C 1 ATOM 1810 O O . VAL B 2 52 ? -33.399 29.247 -4.333 1.00 36.46 ? 259 VAL B O 1 ATOM 1811 C CB . VAL B 2 52 ? -34.372 26.679 -2.812 1.00 35.79 ? 259 VAL B CB 1 ATOM 1812 C CG1 . VAL B 2 52 ? -33.755 25.679 -3.764 1.00 38.64 ? 259 VAL B CG1 1 ATOM 1813 C CG2 . VAL B 2 52 ? -34.822 25.948 -1.563 1.00 33.98 ? 259 VAL B CG2 1 ATOM 1814 N N . THR B 2 53 ? -31.491 28.118 -3.935 1.00 37.93 ? 260 THR B N 1 ATOM 1815 C CA . THR B 2 53 ? -30.698 28.853 -4.921 1.00 32.72 ? 260 THR B CA 1 ATOM 1816 C C . THR B 2 53 ? -30.282 27.991 -6.110 1.00 37.02 ? 260 THR B C 1 ATOM 1817 O O . THR B 2 53 ? -29.614 26.963 -5.950 1.00 38.93 ? 260 THR B O 1 ATOM 1818 C CB . THR B 2 53 ? -29.454 29.486 -4.282 1.00 31.72 ? 260 THR B CB 1 ATOM 1819 O OG1 . THR B 2 53 ? -29.834 30.247 -3.125 1.00 31.34 ? 260 THR B OG1 1 ATOM 1820 C CG2 . THR B 2 53 ? -28.763 30.394 -5.269 1.00 31.36 ? 260 THR B CG2 1 ATOM 1821 N N . CYS B 2 54 ? -30.667 28.431 -7.304 1.00 30.59 ? 261 CYS B N 1 ATOM 1822 C CA . CYS B 2 54 ? -30.358 27.694 -8.521 1.00 31.90 ? 261 CYS B CA 1 ATOM 1823 C C . CYS B 2 54 ? -29.303 28.460 -9.301 1.00 32.88 ? 261 CYS B C 1 ATOM 1824 O O . CYS B 2 54 ? -29.568 29.564 -9.800 1.00 29.38 ? 261 CYS B O 1 ATOM 1825 C CB . CYS B 2 54 ? -31.610 27.512 -9.361 1.00 33.88 ? 261 CYS B CB 1 ATOM 1826 S SG . CYS B 2 54 ? -31.439 26.314 -10.696 1.00 36.23 ? 261 CYS B SG 1 ATOM 1827 N N . VAL B 2 55 ? -28.108 27.872 -9.389 1.00 29.27 ? 262 VAL B N 1 ATOM 1828 C CA . VAL B 2 55 ? -26.938 28.519 -9.999 1.00 29.30 ? 262 VAL B CA 1 ATOM 1829 C C . VAL B 2 55 ? -26.590 27.840 -11.321 1.00 32.28 ? 262 VAL B C 1 ATOM 1830 O O . VAL B 2 55 ? -26.165 26.685 -11.324 1.00 38.39 ? 262 VAL B O 1 ATOM 1831 C CB . VAL B 2 55 ? -25.718 28.430 -9.065 1.00 30.60 ? 262 VAL B CB 1 ATOM 1832 C CG1 . VAL B 2 55 ? -24.524 29.165 -9.666 1.00 39.53 ? 262 VAL B CG1 1 ATOM 1833 C CG2 . VAL B 2 55 ? -26.045 28.983 -7.681 1.00 28.26 ? 262 VAL B CG2 1 ATOM 1834 N N . VAL B 2 56 ? -26.799 28.546 -12.431 1.00 30.97 ? 263 VAL B N 1 ATOM 1835 C CA . VAL B 2 56 ? -26.418 28.072 -13.762 1.00 29.89 ? 263 VAL B CA 1 ATOM 1836 C C . VAL B 2 56 ? -25.058 28.686 -14.130 1.00 40.53 ? 263 VAL B C 1 ATOM 1837 O O . VAL B 2 56 ? -24.882 29.909 -14.030 1.00 41.18 ? 263 VAL B O 1 ATOM 1838 C CB . VAL B 2 56 ? -27.441 28.496 -14.836 1.00 33.78 ? 263 VAL B CB 1 ATOM 1839 C CG1 . VAL B 2 56 ? -27.135 27.833 -16.173 1.00 35.31 ? 263 VAL B CG1 1 ATOM 1840 C CG2 . VAL B 2 56 ? -28.865 28.176 -14.419 1.00 30.81 ? 263 VAL B CG2 1 ATOM 1841 N N . VAL B 2 57 ? -24.100 27.842 -14.532 1.00 41.36 ? 264 VAL B N 1 ATOM 1842 C CA . VAL B 2 57 ? -22.778 28.318 -14.999 1.00 37.84 ? 264 VAL B CA 1 ATOM 1843 C C . VAL B 2 57 ? -22.548 28.003 -16.481 1.00 46.56 ? 264 VAL B C 1 ATOM 1844 O O . VAL B 2 57 ? -23.442 27.484 -17.147 1.00 44.29 ? 264 VAL B O 1 ATOM 1845 C CB . VAL B 2 57 ? -21.611 27.807 -14.137 1.00 35.13 ? 264 VAL B CB 1 ATOM 1846 C CG1 . VAL B 2 57 ? -21.696 28.390 -12.729 1.00 33.05 ? 264 VAL B CG1 1 ATOM 1847 C CG2 . VAL B 2 57 ? -21.578 26.286 -14.100 1.00 43.76 ? 264 VAL B CG2 1 ATOM 1848 N N . ASP B 2 58 ? -21.366 28.347 -16.995 1.00 47.64 ? 265 ASP B N 1 ATOM 1849 C CA . ASP B 2 58 ? -21.020 28.125 -18.405 1.00 53.28 ? 265 ASP B CA 1 ATOM 1850 C C . ASP B 2 58 ? -22.095 28.625 -19.371 1.00 55.92 ? 265 ASP B C 1 ATOM 1851 O O . ASP B 2 58 ? -22.394 27.979 -20.380 1.00 56.42 ? 265 ASP B O 1 ATOM 1852 C CB . ASP B 2 58 ? -20.707 26.642 -18.668 1.00 62.06 ? 265 ASP B CB 1 ATOM 1853 C CG . ASP B 2 58 ? -19.489 26.153 -17.908 1.00 70.99 ? 265 ASP B CG 1 ATOM 1854 O OD1 . ASP B 2 58 ? -19.090 26.797 -16.912 1.00 71.35 ? 265 ASP B OD1 1 ATOM 1855 O OD2 . ASP B 2 58 ? -18.932 25.112 -18.310 1.00 80.55 ? 265 ASP B OD2 1 ATOM 1856 N N . VAL B 2 59 ? -22.685 29.770 -19.044 1.00 61.19 ? 266 VAL B N 1 ATOM 1857 C CA . VAL B 2 59 ? -23.660 30.411 -19.919 1.00 58.12 ? 266 VAL B CA 1 ATOM 1858 C C . VAL B 2 59 ? -22.897 31.272 -20.925 1.00 55.96 ? 266 VAL B C 1 ATOM 1859 O O . VAL B 2 59 ? -22.087 32.118 -20.537 1.00 52.70 ? 266 VAL B O 1 ATOM 1860 C CB . VAL B 2 59 ? -24.720 31.198 -19.107 1.00 53.85 ? 266 VAL B CB 1 ATOM 1861 C CG1 . VAL B 2 59 ? -25.325 32.340 -19.907 1.00 50.25 ? 266 VAL B CG1 1 ATOM 1862 C CG2 . VAL B 2 59 ? -25.812 30.253 -18.634 1.00 49.49 ? 266 VAL B CG2 1 ATOM 1863 N N . SER B 2 60 ? -23.148 31.029 -22.212 1.00 46.00 ? 267 SER B N 1 ATOM 1864 C CA . SER B 2 60 ? -22.371 31.643 -23.283 1.00 50.55 ? 267 SER B CA 1 ATOM 1865 C C . SER B 2 60 ? -22.731 33.107 -23.527 1.00 63.26 ? 267 SER B C 1 ATOM 1866 O O . SER B 2 60 ? -23.888 33.514 -23.360 1.00 65.13 ? 267 SER B O 1 ATOM 1867 C CB . SER B 2 60 ? -22.512 30.836 -24.579 1.00 47.99 ? 267 SER B CB 1 ATOM 1868 O OG . SER B 2 60 ? -23.778 31.020 -25.175 1.00 43.49 ? 267 SER B OG 1 ATOM 1869 N N . HIS B 2 61 ? -21.723 33.886 -23.917 1.00 62.37 ? 268 HIS B N 1 ATOM 1870 C CA . HIS B 2 61 ? -21.907 35.257 -24.394 1.00 59.02 ? 268 HIS B CA 1 ATOM 1871 C C . HIS B 2 61 ? -22.907 35.349 -25.514 1.00 62.44 ? 268 HIS B C 1 ATOM 1872 O O . HIS B 2 61 ? -23.724 36.271 -25.542 1.00 66.26 ? 268 HIS B O 1 ATOM 1873 C CB . HIS B 2 61 ? -20.576 35.826 -24.875 1.00 69.67 ? 268 HIS B CB 1 ATOM 1874 C CG . HIS B 2 61 ? -19.891 36.719 -23.871 1.00 76.29 ? 268 HIS B CG 1 ATOM 1875 N ND1 . HIS B 2 61 ? -19.299 36.241 -22.762 1.00 80.86 ? 268 HIS B ND1 1 ATOM 1876 C CD2 . HIS B 2 61 ? -19.710 38.101 -23.851 1.00 82.93 ? 268 HIS B CD2 1 ATOM 1877 C CE1 . HIS B 2 61 ? -18.769 37.262 -22.063 1.00 82.79 ? 268 HIS B CE1 1 ATOM 1878 N NE2 . HIS B 2 61 ? -19.023 38.401 -22.730 1.00 89.14 ? 268 HIS B NE2 1 ATOM 1879 N N . GLU B 2 62 ? -22.848 34.392 -26.442 1.00 60.84 ? 269 GLU B N 1 ATOM 1880 C CA . GLU B 2 62 ? -23.639 34.424 -27.681 1.00 70.58 ? 269 GLU B CA 1 ATOM 1881 C C . GLU B 2 62 ? -25.127 34.150 -27.466 1.00 74.83 ? 269 GLU B C 1 ATOM 1882 O O . GLU B 2 62 ? -25.963 34.594 -28.255 1.00 64.22 ? 269 GLU B O 1 ATOM 1883 C CB . GLU B 2 62 ? -23.060 33.456 -28.723 1.00 66.75 ? 269 GLU B CB 1 ATOM 1884 N N . ASP B 2 63 ? -25.444 33.405 -26.407 1.00 82.65 ? 270 ASP B N 1 ATOM 1885 C CA . ASP B 2 63 ? -26.829 33.158 -25.995 1.00 72.95 ? 270 ASP B CA 1 ATOM 1886 C C . ASP B 2 63 ? -26.918 33.094 -24.463 1.00 69.77 ? 270 ASP B C 1 ATOM 1887 O O . ASP B 2 63 ? -26.767 32.019 -23.875 1.00 69.63 ? 270 ASP B O 1 ATOM 1888 C CB . ASP B 2 63 ? -27.371 31.876 -26.642 1.00 65.72 ? 270 ASP B CB 1 ATOM 1889 N N . PRO B 2 64 ? -27.138 34.254 -23.808 1.00 60.65 ? 271 PRO B N 1 ATOM 1890 C CA . PRO B 2 64 ? -27.181 34.305 -22.347 1.00 53.56 ? 271 PRO B CA 1 ATOM 1891 C C . PRO B 2 64 ? -28.576 34.147 -21.724 1.00 55.55 ? 271 PRO B C 1 ATOM 1892 O O . PRO B 2 64 ? -28.693 34.166 -20.494 1.00 57.26 ? 271 PRO B O 1 ATOM 1893 C CB . PRO B 2 64 ? -26.618 35.701 -22.024 1.00 52.73 ? 271 PRO B CB 1 ATOM 1894 C CG . PRO B 2 64 ? -26.407 36.393 -23.338 1.00 55.56 ? 271 PRO B CG 1 ATOM 1895 C CD . PRO B 2 64 ? -27.147 35.609 -24.379 1.00 50.92 ? 271 PRO B CD 1 ATOM 1896 N N . GLU B 2 65 ? -29.605 33.990 -22.558 1.00 52.09 ? 272 GLU B N 1 ATOM 1897 C CA . GLU B 2 65 ? -30.991 33.837 -22.094 1.00 56.82 ? 272 GLU B CA 1 ATOM 1898 C C . GLU B 2 65 ? -31.187 32.542 -21.328 1.00 52.26 ? 272 GLU B C 1 ATOM 1899 O O . GLU B 2 65 ? -30.979 31.458 -21.867 1.00 54.72 ? 272 GLU B O 1 ATOM 1900 C CB . GLU B 2 65 ? -31.980 33.878 -23.264 1.00 58.65 ? 272 GLU B CB 1 ATOM 1901 C CG . GLU B 2 65 ? -32.155 35.247 -23.896 1.00 69.52 ? 272 GLU B CG 1 ATOM 1902 C CD . GLU B 2 65 ? -30.905 35.727 -24.611 1.00 73.99 ? 272 GLU B CD 1 ATOM 1903 O OE1 . GLU B 2 65 ? -30.279 34.923 -25.340 1.00 67.08 ? 272 GLU B OE1 1 ATOM 1904 O OE2 . GLU B 2 65 ? -30.548 36.909 -24.432 1.00 71.35 ? 272 GLU B OE2 1 ATOM 1905 N N . VAL B 2 66 ? -31.587 32.659 -20.067 1.00 57.14 ? 273 VAL B N 1 ATOM 1906 C CA . VAL B 2 66 ? -31.851 31.480 -19.246 1.00 54.37 ? 273 VAL B CA 1 ATOM 1907 C C . VAL B 2 66 ? -33.268 31.481 -18.667 1.00 49.76 ? 273 VAL B C 1 ATOM 1908 O O . VAL B 2 66 ? -33.603 32.300 -17.806 1.00 56.61 ? 273 VAL B O 1 ATOM 1909 C CB . VAL B 2 66 ? -30.804 31.308 -18.130 1.00 51.84 ? 273 VAL B CB 1 ATOM 1910 C CG1 . VAL B 2 66 ? -31.053 30.017 -17.363 1.00 54.16 ? 273 VAL B CG1 1 ATOM 1911 C CG2 . VAL B 2 66 ? -29.403 31.304 -18.712 1.00 54.56 ? 273 VAL B CG2 1 ATOM 1912 N N . LYS B 2 67 ? -34.084 30.558 -19.167 1.00 40.09 ? 274 LYS B N 1 ATOM 1913 C CA . LYS B 2 67 ? -35.435 30.314 -18.677 1.00 42.40 ? 274 LYS B CA 1 ATOM 1914 C C . LYS B 2 67 ? -35.407 29.433 -17.424 1.00 45.65 ? 274 LYS B C 1 ATOM 1915 O O . LYS B 2 67 ? -34.840 28.332 -17.441 1.00 48.61 ? 274 LYS B O 1 ATOM 1916 C CB . LYS B 2 67 ? -36.258 29.634 -19.772 1.00 42.18 ? 274 LYS B CB 1 ATOM 1917 C CG . LYS B 2 67 ? -37.701 29.337 -19.413 1.00 46.46 ? 274 LYS B CG 1 ATOM 1918 C CD . LYS B 2 67 ? -38.567 30.578 -19.553 1.00 58.53 ? 274 LYS B CD 1 ATOM 1919 C CE . LYS B 2 67 ? -39.987 30.332 -19.063 1.00 62.77 ? 274 LYS B CE 1 ATOM 1920 N NZ . LYS B 2 67 ? -40.641 29.174 -19.740 1.00 57.42 ? 274 LYS B NZ 1 ATOM 1921 N N . PHE B 2 68 ? -36.011 29.927 -16.345 1.00 39.84 ? 275 PHE B N 1 ATOM 1922 C CA . PHE B 2 68 ? -36.141 29.171 -15.091 1.00 34.50 ? 275 PHE B CA 1 ATOM 1923 C C . PHE B 2 68 ? -37.587 28.749 -14.852 1.00 37.36 ? 275 PHE B C 1 ATOM 1924 O O . PHE B 2 68 ? -38.497 29.580 -14.870 1.00 39.41 ? 275 PHE B O 1 ATOM 1925 C CB . PHE B 2 68 ? -35.687 30.009 -13.903 1.00 37.72 ? 275 PHE B CB 1 ATOM 1926 C CG . PHE B 2 68 ? -34.205 30.180 -13.807 1.00 41.29 ? 275 PHE B CG 1 ATOM 1927 C CD1 . PHE B 2 68 ? -33.591 31.306 -14.345 1.00 42.22 ? 275 PHE B CD1 1 ATOM 1928 C CD2 . PHE B 2 68 ? -33.422 29.233 -13.156 1.00 40.70 ? 275 PHE B CD2 1 ATOM 1929 C CE1 . PHE B 2 68 ? -32.221 31.480 -14.249 1.00 38.81 ? 275 PHE B CE1 1 ATOM 1930 C CE2 . PHE B 2 68 ? -32.052 29.402 -13.054 1.00 41.60 ? 275 PHE B CE2 1 ATOM 1931 C CZ . PHE B 2 68 ? -31.451 30.530 -13.604 1.00 37.45 ? 275 PHE B CZ 1 ATOM 1932 N N . ASN B 2 69 ? -37.789 27.452 -14.643 1.00 42.98 ? 276 ASN B N 1 ATOM 1933 C CA . ASN B 2 69 ? -39.078 26.915 -14.239 1.00 39.40 ? 276 ASN B CA 1 ATOM 1934 C C . ASN B 2 69 ? -38.920 26.251 -12.879 1.00 43.34 ? 276 ASN B C 1 ATOM 1935 O O . ASN B 2 69 ? -38.203 25.259 -12.754 1.00 49.51 ? 276 ASN B O 1 ATOM 1936 C CB . ASN B 2 69 ? -39.577 25.902 -15.259 1.00 41.15 ? 276 ASN B CB 1 ATOM 1937 C CG . ASN B 2 69 ? -40.095 26.548 -16.531 1.00 48.30 ? 276 ASN B CG 1 ATOM 1938 O OD1 . ASN B 2 69 ? -39.446 26.495 -17.571 1.00 47.99 ? 276 ASN B OD1 1 ATOM 1939 N ND2 . ASN B 2 69 ? -41.281 27.144 -16.457 1.00 56.17 ? 276 ASN B ND2 1 ATOM 1940 N N . TRP B 2 70 ? -39.561 26.813 -11.860 1.00 35.23 ? 277 TRP B N 1 ATOM 1941 C CA . TRP B 2 70 ? -39.533 26.227 -10.517 1.00 34.44 ? 277 TRP B CA 1 ATOM 1942 C C . TRP B 2 70 ? -40.765 25.424 -10.219 1.00 42.33 ? 277 TRP B C 1 ATOM 1943 O O . TRP B 2 70 ? -41.876 25.805 -10.603 1.00 42.18 ? 277 TRP B O 1 ATOM 1944 C CB . TRP B 2 70 ? -39.386 27.306 -9.462 1.00 28.45 ? 277 TRP B CB 1 ATOM 1945 C CG . TRP B 2 70 ? -38.002 27.901 -9.370 1.00 35.91 ? 277 TRP B CG 1 ATOM 1946 C CD1 . TRP B 2 70 ? -37.460 28.913 -10.153 1.00 40.60 ? 277 TRP B CD1 1 ATOM 1947 C CD2 . TRP B 2 70 ? -36.943 27.557 -8.409 1.00 41.03 ? 277 TRP B CD2 1 ATOM 1948 N NE1 . TRP B 2 70 ? -36.182 29.207 -9.759 1.00 39.64 ? 277 TRP B NE1 1 ATOM 1949 C CE2 . TRP B 2 70 ? -35.809 28.432 -8.720 1.00 43.55 ? 277 TRP B CE2 1 ATOM 1950 C CE3 . TRP B 2 70 ? -36.826 26.647 -7.362 1.00 39.33 ? 277 TRP B CE3 1 ATOM 1951 C CZ2 . TRP B 2 70 ? -34.622 28.382 -8.001 1.00 39.62 ? 277 TRP B CZ2 1 ATOM 1952 C CZ3 . TRP B 2 70 ? -35.629 26.605 -6.646 1.00 36.27 ? 277 TRP B CZ3 1 ATOM 1953 C CH2 . TRP B 2 70 ? -34.551 27.450 -6.960 1.00 41.27 ? 277 TRP B CH2 1 ATOM 1954 N N . TYR B 2 71 ? -40.576 24.303 -9.524 1.00 39.89 ? 278 TYR B N 1 ATOM 1955 C CA . TYR B 2 71 ? -41.686 23.462 -9.098 1.00 37.87 ? 278 TYR B CA 1 ATOM 1956 C C . TYR B 2 71 ? -41.556 23.080 -7.624 1.00 37.72 ? 278 TYR B C 1 ATOM 1957 O O . TYR B 2 71 ? -40.464 22.794 -7.143 1.00 41.39 ? 278 TYR B O 1 ATOM 1958 C CB . TYR B 2 71 ? -41.756 22.211 -9.962 1.00 39.45 ? 278 TYR B CB 1 ATOM 1959 C CG . TYR B 2 71 ? -41.764 22.483 -11.458 1.00 43.74 ? 278 TYR B CG 1 ATOM 1960 C CD1 . TYR B 2 71 ? -40.572 22.611 -12.169 1.00 41.09 ? 278 TYR B CD1 1 ATOM 1961 C CD2 . TYR B 2 71 ? -42.965 22.601 -12.162 1.00 36.90 ? 278 TYR B CD2 1 ATOM 1962 C CE1 . TYR B 2 71 ? -40.577 22.850 -13.539 1.00 46.29 ? 278 TYR B CE1 1 ATOM 1963 C CE2 . TYR B 2 71 ? -42.976 22.842 -13.533 1.00 37.64 ? 278 TYR B CE2 1 ATOM 1964 C CZ . TYR B 2 71 ? -41.782 22.968 -14.211 1.00 40.92 ? 278 TYR B CZ 1 ATOM 1965 O OH . TYR B 2 71 ? -41.786 23.209 -15.565 1.00 53.37 ? 278 TYR B OH 1 ATOM 1966 N N . VAL B 2 72 ? -42.676 23.098 -6.914 1.00 36.51 ? 279 VAL B N 1 ATOM 1967 C CA . VAL B 2 72 ? -42.732 22.651 -5.525 1.00 36.71 ? 279 VAL B CA 1 ATOM 1968 C C . VAL B 2 72 ? -43.659 21.434 -5.522 1.00 41.96 ? 279 VAL B C 1 ATOM 1969 O O . VAL B 2 72 ? -44.851 21.553 -5.828 1.00 39.97 ? 279 VAL B O 1 ATOM 1970 C CB . VAL B 2 72 ? -43.252 23.763 -4.585 1.00 36.21 ? 279 VAL B CB 1 ATOM 1971 C CG1 . VAL B 2 72 ? -43.217 23.322 -3.125 1.00 41.16 ? 279 VAL B CG1 1 ATOM 1972 C CG2 . VAL B 2 72 ? -42.436 25.031 -4.759 1.00 37.63 ? 279 VAL B CG2 1 ATOM 1973 N N . ASP B 2 73 ? -43.098 20.265 -5.219 1.00 40.32 ? 280 ASP B N 1 ATOM 1974 C CA . ASP B 2 73 ? -43.818 19.001 -5.335 1.00 40.23 ? 280 ASP B CA 1 ATOM 1975 C C . ASP B 2 73 ? -44.560 18.877 -6.673 1.00 40.79 ? 280 ASP B C 1 ATOM 1976 O O . ASP B 2 73 ? -45.717 18.472 -6.705 1.00 45.43 ? 280 ASP B O 1 ATOM 1977 C CB . ASP B 2 73 ? -44.791 18.821 -4.162 1.00 41.66 ? 280 ASP B CB 1 ATOM 1978 C CG . ASP B 2 73 ? -44.079 18.674 -2.824 1.00 48.83 ? 280 ASP B CG 1 ATOM 1979 O OD1 . ASP B 2 73 ? -42.942 18.153 -2.799 1.00 39.69 ? 280 ASP B OD1 1 ATOM 1980 O OD2 . ASP B 2 73 ? -44.669 19.073 -1.796 1.00 48.09 ? 280 ASP B OD2 1 ATOM 1981 N N . GLY B 2 74 ? -43.889 19.242 -7.765 1.00 41.14 ? 281 GLY B N 1 ATOM 1982 C CA . GLY B 2 74 ? -44.425 19.098 -9.125 1.00 35.55 ? 281 GLY B CA 1 ATOM 1983 C C . GLY B 2 74 ? -45.380 20.192 -9.586 1.00 39.45 ? 281 GLY B C 1 ATOM 1984 O O . GLY B 2 74 ? -45.841 20.178 -10.731 1.00 42.14 ? 281 GLY B O 1 ATOM 1985 N N . VAL B 2 75 ? -45.676 21.136 -8.698 1.00 37.18 ? 282 VAL B N 1 ATOM 1986 C CA . VAL B 2 75 ? -46.600 22.242 -8.979 1.00 41.74 ? 282 VAL B CA 1 ATOM 1987 C C . VAL B 2 75 ? -45.799 23.525 -9.230 1.00 45.26 ? 282 VAL B C 1 ATOM 1988 O O . VAL B 2 75 ? -45.024 23.960 -8.370 1.00 42.96 ? 282 VAL B O 1 ATOM 1989 C CB . VAL B 2 75 ? -47.608 22.448 -7.818 1.00 48.54 ? 282 VAL B CB 1 ATOM 1990 C CG1 . VAL B 2 75 ? -48.564 23.600 -8.107 1.00 47.69 ? 282 VAL B CG1 1 ATOM 1991 C CG2 . VAL B 2 75 ? -48.393 21.167 -7.554 1.00 45.56 ? 282 VAL B CG2 1 ATOM 1992 N N . GLU B 2 76 ? -45.980 24.109 -10.416 1.00 47.16 ? 283 GLU B N 1 ATOM 1993 C CA . GLU B 2 76 ? -45.198 25.268 -10.853 1.00 38.12 ? 283 GLU B CA 1 ATOM 1994 C C . GLU B 2 76 ? -45.510 26.497 -10.037 1.00 34.70 ? 283 GLU B C 1 ATOM 1995 O O . GLU B 2 76 ? -46.673 26.818 -9.815 1.00 35.72 ? 283 GLU B O 1 ATOM 1996 C CB . GLU B 2 76 ? -45.427 25.574 -12.335 1.00 32.30 ? 283 GLU B CB 1 ATOM 1997 C CG . GLU B 2 76 ? -44.653 26.788 -12.815 1.00 30.45 ? 283 GLU B CG 1 ATOM 1998 C CD . GLU B 2 76 ? -44.501 26.855 -14.324 1.00 38.61 ? 283 GLU B CD 1 ATOM 1999 O OE1 . GLU B 2 76 ? -45.301 26.236 -15.050 1.00 42.18 ? 283 GLU B OE1 1 ATOM 2000 O OE2 . GLU B 2 76 ? -43.566 27.534 -14.786 1.00 42.39 ? 283 GLU B OE2 1 ATOM 2001 N N . VAL B 2 77 ? -44.459 27.181 -9.595 1.00 35.70 ? 284 VAL B N 1 ATOM 2002 C CA . VAL B 2 77 ? -44.605 28.401 -8.801 1.00 37.10 ? 284 VAL B CA 1 ATOM 2003 C C . VAL B 2 77 ? -43.890 29.527 -9.529 1.00 39.67 ? 284 VAL B C 1 ATOM 2004 O O . VAL B 2 77 ? -43.027 29.268 -10.366 1.00 44.70 ? 284 VAL B O 1 ATOM 2005 C CB . VAL B 2 77 ? -44.067 28.232 -7.360 1.00 38.05 ? 284 VAL B CB 1 ATOM 2006 C CG1 . VAL B 2 77 ? -44.912 27.226 -6.595 1.00 33.19 ? 284 VAL B CG1 1 ATOM 2007 C CG2 . VAL B 2 77 ? -42.599 27.811 -7.364 1.00 40.46 ? 284 VAL B CG2 1 ATOM 2008 N N . HIS B 2 78 ? -44.245 30.769 -9.217 1.00 39.31 ? 285 HIS B N 1 ATOM 2009 C CA . HIS B 2 78 ? -43.833 31.891 -10.061 1.00 40.88 ? 285 HIS B CA 1 ATOM 2010 C C . HIS B 2 78 ? -43.153 33.017 -9.330 1.00 38.28 ? 285 HIS B C 1 ATOM 2011 O O . HIS B 2 78 ? -42.832 34.035 -9.944 1.00 33.67 ? 285 HIS B O 1 ATOM 2012 C CB . HIS B 2 78 ? -45.027 32.403 -10.869 1.00 43.91 ? 285 HIS B CB 1 ATOM 2013 C CG . HIS B 2 78 ? -45.616 31.372 -11.806 1.00 42.07 ? 285 HIS B CG 1 ATOM 2014 N ND1 . HIS B 2 78 ? -46.488 30.426 -11.390 1.00 43.16 ? 285 HIS B ND1 1 ATOM 2015 C CD2 . HIS B 2 78 ? -45.423 31.157 -13.173 1.00 39.14 ? 285 HIS B CD2 1 ATOM 2016 C CE1 . HIS B 2 78 ? -46.842 29.649 -12.436 1.00 41.47 ? 285 HIS B CE1 1 ATOM 2017 N NE2 . HIS B 2 78 ? -46.189 30.098 -13.528 1.00 44.80 ? 285 HIS B NE2 1 ATOM 2018 N N . ASN B 2 79 ? -42.901 32.846 -8.030 1.00 29.98 ? 286 ASN B N 1 ATOM 2019 C CA . ASN B 2 79 ? -42.289 33.914 -7.227 1.00 32.12 ? 286 ASN B CA 1 ATOM 2020 C C . ASN B 2 79 ? -40.742 33.987 -7.191 1.00 32.74 ? 286 ASN B C 1 ATOM 2021 O O . ASN B 2 79 ? -40.183 34.805 -6.450 1.00 36.10 ? 286 ASN B O 1 ATOM 2022 C CB . ASN B 2 79 ? -42.858 33.920 -5.795 1.00 35.59 ? 286 ASN B CB 1 ATOM 2023 C CG . ASN B 2 79 ? -42.671 32.597 -5.079 1.00 37.73 ? 286 ASN B CG 1 ATOM 2024 O OD1 . ASN B 2 79 ? -42.819 31.524 -5.666 1.00 39.71 ? 286 ASN B OD1 1 ATOM 2025 N ND2 . ASN B 2 79 ? -42.357 32.668 -3.793 1.00 49.22 ? 286 ASN B ND2 1 ATOM 2026 N N . ALA B 2 80 ? -40.062 33.154 -7.981 1.00 29.20 ? 287 ALA B N 1 ATOM 2027 C CA . ALA B 2 80 ? -38.590 33.183 -8.068 1.00 33.97 ? 287 ALA B CA 1 ATOM 2028 C C . ALA B 2 80 ? -38.076 34.511 -8.614 1.00 38.40 ? 287 ALA B C 1 ATOM 2029 O O . ALA B 2 80 ? -38.658 35.078 -9.535 1.00 43.67 ? 287 ALA B O 1 ATOM 2030 C CB . ALA B 2 80 ? -38.075 32.040 -8.930 1.00 27.41 ? 287 ALA B CB 1 ATOM 2031 N N . LYS B 2 81 ? -36.977 34.988 -8.041 1.00 41.75 ? 288 LYS B N 1 ATOM 2032 C CA . LYS B 2 81 ? -36.357 36.245 -8.441 1.00 40.99 ? 288 LYS B CA 1 ATOM 2033 C C . LYS B 2 81 ? -34.931 36.005 -8.940 1.00 45.41 ? 288 LYS B C 1 ATOM 2034 O O . LYS B 2 81 ? -34.108 35.392 -8.248 1.00 41.36 ? 288 LYS B O 1 ATOM 2035 C CB . LYS B 2 81 ? -36.343 37.221 -7.267 1.00 43.65 ? 288 LYS B CB 1 ATOM 2036 C CG . LYS B 2 81 ? -37.714 37.753 -6.876 1.00 52.07 ? 288 LYS B CG 1 ATOM 2037 C CD . LYS B 2 81 ? -37.752 38.248 -5.431 1.00 61.00 ? 288 LYS B CD 1 ATOM 2038 C CE . LYS B 2 81 ? -36.736 39.350 -5.149 1.00 76.08 ? 288 LYS B CE 1 ATOM 2039 N NZ . LYS B 2 81 ? -36.976 40.580 -5.956 1.00 89.36 ? 288 LYS B NZ 1 ATOM 2040 N N . THR B 2 82 ? -34.649 36.483 -10.149 1.00 41.05 ? 289 THR B N 1 ATOM 2041 C CA . THR B 2 82 ? -33.327 36.353 -10.749 1.00 39.67 ? 289 THR B CA 1 ATOM 2042 C C . THR B 2 82 ? -32.384 37.427 -10.225 1.00 36.03 ? 289 THR B C 1 ATOM 2043 O O . THR B 2 82 ? -32.740 38.603 -10.173 1.00 36.92 ? 289 THR B O 1 ATOM 2044 C CB . THR B 2 82 ? -33.400 36.422 -12.281 1.00 40.98 ? 289 THR B CB 1 ATOM 2045 O OG1 . THR B 2 82 ? -34.367 35.479 -12.742 1.00 41.41 ? 289 THR B OG1 1 ATOM 2046 C CG2 . THR B 2 82 ? -32.056 36.083 -12.915 1.00 42.36 ? 289 THR B CG2 1 ATOM 2047 N N . LYS B 2 83 ? -31.190 36.988 -9.822 1.00 36.79 ? 290 LYS B N 1 ATOM 2048 C CA . LYS B 2 83 ? -30.125 37.844 -9.296 1.00 30.11 ? 290 LYS B CA 1 ATOM 2049 C C . LYS B 2 83 ? -29.445 38.622 -10.424 1.00 30.92 ? 290 LYS B C 1 ATOM 2050 O O . LYS B 2 83 ? -29.564 38.246 -11.597 1.00 26.18 ? 290 LYS B O 1 ATOM 2051 C CB . LYS B 2 83 ? -29.088 36.978 -8.567 1.00 35.43 ? 290 LYS B CB 1 ATOM 2052 C CG . LYS B 2 83 ? -29.477 36.560 -7.150 1.00 37.18 ? 290 LYS B CG 1 ATOM 2053 C CD . LYS B 2 83 ? -29.324 37.728 -6.190 1.00 41.95 ? 290 LYS B CD 1 ATOM 2054 C CE . LYS B 2 83 ? -29.435 37.289 -4.743 1.00 52.83 ? 290 LYS B CE 1 ATOM 2055 N NZ . LYS B 2 83 ? -28.885 38.334 -3.838 1.00 56.12 ? 290 LYS B NZ 1 ATOM 2056 N N . PRO B 2 84 ? -28.732 39.708 -10.082 1.00 30.58 ? 291 PRO B N 1 ATOM 2057 C CA . PRO B 2 84 ? -27.966 40.426 -11.104 1.00 30.52 ? 291 PRO B CA 1 ATOM 2058 C C . PRO B 2 84 ? -26.959 39.488 -11.757 1.00 34.99 ? 291 PRO B C 1 ATOM 2059 O O . PRO B 2 84 ? -26.195 38.824 -11.058 1.00 31.10 ? 291 PRO B O 1 ATOM 2060 C CB . PRO B 2 84 ? -27.230 41.506 -10.314 1.00 33.63 ? 291 PRO B CB 1 ATOM 2061 C CG . PRO B 2 84 ? -27.966 41.625 -9.021 1.00 32.59 ? 291 PRO B CG 1 ATOM 2062 C CD . PRO B 2 84 ? -28.537 40.278 -8.735 1.00 33.18 ? 291 PRO B CD 1 ATOM 2063 N N . ARG B 2 85 ? -27.012 39.412 -13.088 1.00 32.45 ? 292 ARG B N 1 ATOM 2064 C CA . ARG B 2 85 ? -26.130 38.590 -13.888 1.00 31.29 ? 292 ARG B CA 1 ATOM 2065 C C . ARG B 2 85 ? -24.667 38.970 -13.646 1.00 38.56 ? 292 ARG B C 1 ATOM 2066 O O . ARG B 2 85 ? -24.343 40.152 -13.533 1.00 35.55 ? 292 ARG B O 1 ATOM 2067 C CB . ARG B 2 85 ? -26.470 38.803 -15.365 1.00 34.90 ? 292 ARG B CB 1 ATOM 2068 C CG . ARG B 2 85 ? -25.742 37.876 -16.314 1.00 36.31 ? 292 ARG B CG 1 ATOM 2069 C CD . ARG B 2 85 ? -26.273 38.029 -17.727 1.00 34.73 ? 292 ARG B CD 1 ATOM 2070 N NE . ARG B 2 85 ? -25.815 39.260 -18.363 1.00 38.80 ? 292 ARG B NE 1 ATOM 2071 C CZ . ARG B 2 85 ? -25.940 39.513 -19.667 1.00 40.59 ? 292 ARG B CZ 1 ATOM 2072 N NH1 . ARG B 2 85 ? -26.499 38.621 -20.472 1.00 41.92 ? 292 ARG B NH1 1 ATOM 2073 N NH2 . ARG B 2 85 ? -25.503 40.654 -20.170 1.00 34.41 ? 292 ARG B NH2 1 ATOM 2074 N N . GLU B 2 86 ? -23.793 37.970 -13.549 1.00 37.80 ? 293 GLU B N 1 ATOM 2075 C CA . GLU B 2 86 ? -22.372 38.221 -13.287 1.00 49.05 ? 293 GLU B CA 1 ATOM 2076 C C . GLU B 2 86 ? -21.473 37.655 -14.383 1.00 51.96 ? 293 GLU B C 1 ATOM 2077 O O . GLU B 2 86 ? -21.635 36.504 -14.805 1.00 49.23 ? 293 GLU B O 1 ATOM 2078 C CB . GLU B 2 86 ? -21.956 37.682 -11.912 1.00 41.06 ? 293 GLU B CB 1 ATOM 2079 N N . GLU B 2 87 ? -20.539 38.482 -14.846 1.00 63.08 ? 294 GLU B N 1 ATOM 2080 C CA . GLU B 2 87 ? -19.502 38.036 -15.773 1.00 68.27 ? 294 GLU B CA 1 ATOM 2081 C C . GLU B 2 87 ? -18.418 37.346 -14.967 1.00 55.12 ? 294 GLU B C 1 ATOM 2082 O O . GLU B 2 87 ? -17.923 37.898 -13.981 1.00 53.71 ? 294 GLU B O 1 ATOM 2083 C CB . GLU B 2 87 ? -18.908 39.213 -16.561 1.00 80.10 ? 294 GLU B CB 1 ATOM 2084 C CG . GLU B 2 87 ? -17.699 38.869 -17.428 1.00 79.08 ? 294 GLU B CG 1 ATOM 2085 C CD . GLU B 2 87 ? -18.083 38.338 -18.795 1.00 80.92 ? 294 GLU B CD 1 ATOM 2086 O OE1 . GLU B 2 87 ? -17.938 37.118 -19.025 1.00 86.97 ? 294 GLU B OE1 1 ATOM 2087 O OE2 . GLU B 2 87 ? -18.532 39.143 -19.637 1.00 78.68 ? 294 GLU B OE2 1 ATOM 2088 N N . GLN B 2 88 ? -18.077 36.129 -15.380 1.00 59.51 ? 295 GLN B N 1 ATOM 2089 C CA . GLN B 2 88 ? -16.952 35.405 -14.798 1.00 64.76 ? 295 GLN B CA 1 ATOM 2090 C C . GLN B 2 88 ? -15.728 35.598 -15.700 1.00 71.85 ? 295 GLN B C 1 ATOM 2091 O O . GLN B 2 88 ? -15.857 35.683 -16.930 1.00 74.32 ? 295 GLN B O 1 ATOM 2092 C CB . GLN B 2 88 ? -17.286 33.917 -14.608 1.00 61.22 ? 295 GLN B CB 1 ATOM 2093 C CG . GLN B 2 88 ? -18.642 33.629 -13.961 1.00 57.68 ? 295 GLN B CG 1 ATOM 2094 C CD . GLN B 2 88 ? -18.763 34.143 -12.531 1.00 67.97 ? 295 GLN B CD 1 ATOM 2095 O OE1 . GLN B 2 88 ? -18.143 33.610 -11.608 1.00 69.49 ? 295 GLN B OE1 1 ATOM 2096 N NE2 . GLN B 2 88 ? -19.582 35.176 -12.340 1.00 67.51 ? 295 GLN B NE2 1 ATOM 2097 N N . TYR B 2 89 ? -14.549 35.674 -15.084 1.00 60.58 ? 296 TYR B N 1 ATOM 2098 C CA . TYR B 2 89 ? -13.305 35.997 -15.792 1.00 71.61 ? 296 TYR B CA 1 ATOM 2099 C C . TYR B 2 89 ? -13.060 35.149 -17.048 1.00 66.57 ? 296 TYR B C 1 ATOM 2100 O O . TYR B 2 89 ? -12.431 35.609 -18.002 1.00 69.95 ? 296 TYR B O 1 ATOM 2101 C CB . TYR B 2 89 ? -12.108 35.915 -14.836 1.00 63.28 ? 296 TYR B CB 1 ATOM 2102 N N . ASN B 2 90 ? -13.593 33.929 -17.052 1.00 64.86 ? 297 ASN B N 1 ATOM 2103 C CA . ASN B 2 90 ? -13.408 32.985 -18.160 1.00 58.26 ? 297 ASN B CA 1 ATOM 2104 C C . ASN B 2 90 ? -14.371 33.140 -19.348 1.00 53.30 ? 297 ASN B C 1 ATOM 2105 O O . ASN B 2 90 ? -14.632 32.171 -20.069 1.00 54.04 ? 297 ASN B O 1 ATOM 2106 C CB . ASN B 2 90 ? -13.450 31.546 -17.626 1.00 64.92 ? 297 ASN B CB 1 ATOM 2107 C CG . ASN B 2 90 ? -14.676 31.271 -16.763 1.00 63.79 ? 297 ASN B CG 1 ATOM 2108 O OD1 . ASN B 2 90 ? -15.631 32.054 -16.739 1.00 54.11 ? 297 ASN B OD1 1 ATOM 2109 N ND2 . ASN B 2 90 ? -14.648 30.149 -16.049 1.00 60.06 ? 297 ASN B ND2 1 ATOM 2110 N N . SER B 2 91 ? -14.892 34.353 -19.538 1.00 62.15 ? 298 SER B N 1 ATOM 2111 C CA . SER B 2 91 ? -15.760 34.716 -20.680 1.00 70.64 ? 298 SER B CA 1 ATOM 2112 C C . SER B 2 91 ? -17.153 34.059 -20.696 1.00 68.02 ? 298 SER B C 1 ATOM 2113 O O . SER B 2 91 ? -17.787 33.956 -21.756 1.00 61.77 ? 298 SER B O 1 ATOM 2114 C CB . SER B 2 91 ? -15.044 34.495 -22.026 1.00 70.82 ? 298 SER B CB 1 ATOM 2115 O OG . SER B 2 91 ? -15.049 33.122 -22.390 1.00 71.74 ? 298 SER B OG 1 ATOM 2116 N N . THR B 2 92 ? -17.622 33.613 -19.532 1.00 62.50 ? 299 THR B N 1 ATOM 2117 C CA . THR B 2 92 ? -18.984 33.075 -19.406 1.00 57.67 ? 299 THR B CA 1 ATOM 2118 C C . THR B 2 92 ? -19.796 33.798 -18.333 1.00 58.59 ? 299 THR B C 1 ATOM 2119 O O . THR B 2 92 ? -19.232 34.439 -17.428 1.00 54.83 ? 299 THR B O 1 ATOM 2120 C CB . THR B 2 92 ? -19.013 31.553 -19.121 1.00 54.50 ? 299 THR B CB 1 ATOM 2121 O OG1 . THR B 2 92 ? -18.398 31.269 -17.852 1.00 46.39 ? 299 THR B OG1 1 ATOM 2122 C CG2 . THR B 2 92 ? -18.320 30.775 -20.234 1.00 58.00 ? 299 THR B CG2 1 ATOM 2123 N N . TYR B 2 93 ? -21.120 33.684 -18.446 1.00 55.53 ? 300 TYR B N 1 ATOM 2124 C CA . TYR B 2 93 ? -22.034 34.248 -17.455 1.00 60.31 ? 300 TYR B CA 1 ATOM 2125 C C . TYR B 2 93 ? -22.458 33.225 -16.407 1.00 59.47 ? 300 TYR B C 1 ATOM 2126 O O . TYR B 2 93 ? -22.700 32.052 -16.718 1.00 55.63 ? 300 TYR B O 1 ATOM 2127 C CB . TYR B 2 93 ? -23.293 34.824 -18.111 1.00 50.55 ? 300 TYR B CB 1 ATOM 2128 C CG . TYR B 2 93 ? -23.064 35.979 -19.047 1.00 47.92 ? 300 TYR B CG 1 ATOM 2129 C CD1 . TYR B 2 93 ? -23.367 35.861 -20.400 1.00 52.72 ? 300 TYR B CD1 1 ATOM 2130 C CD2 . TYR B 2 93 ? -22.562 37.198 -18.582 1.00 51.13 ? 300 TYR B CD2 1 ATOM 2131 C CE1 . TYR B 2 93 ? -23.169 36.919 -21.272 1.00 61.07 ? 300 TYR B CE1 1 ATOM 2132 C CE2 . TYR B 2 93 ? -22.356 38.262 -19.447 1.00 48.61 ? 300 TYR B CE2 1 ATOM 2133 C CZ . TYR B 2 93 ? -22.663 38.117 -20.789 1.00 58.85 ? 300 TYR B CZ 1 ATOM 2134 O OH . TYR B 2 93 ? -22.466 39.164 -21.660 1.00 68.56 ? 300 TYR B OH 1 ATOM 2135 N N . ARG B 2 94 ? -22.539 33.702 -15.169 1.00 52.00 ? 301 ARG B N 1 ATOM 2136 C CA . ARG B 2 94 ? -23.191 32.998 -14.083 1.00 48.07 ? 301 ARG B CA 1 ATOM 2137 C C . ARG B 2 94 ? -24.590 33.616 -13.896 1.00 49.93 ? 301 ARG B C 1 ATOM 2138 O O . ARG B 2 94 ? -24.729 34.838 -13.723 1.00 49.82 ? 301 ARG B O 1 ATOM 2139 C CB . ARG B 2 94 ? -22.355 33.138 -12.813 1.00 37.23 ? 301 ARG B CB 1 ATOM 2140 C CG . ARG B 2 94 ? -22.734 32.200 -11.678 1.00 44.48 ? 301 ARG B CG 1 ATOM 2141 C CD . ARG B 2 94 ? -21.924 32.563 -10.444 1.00 37.94 ? 301 ARG B CD 1 ATOM 2142 N NE . ARG B 2 94 ? -22.035 31.591 -9.365 1.00 41.65 ? 301 ARG B NE 1 ATOM 2143 C CZ . ARG B 2 94 ? -22.470 31.869 -8.135 1.00 46.46 ? 301 ARG B CZ 1 ATOM 2144 N NH1 . ARG B 2 94 ? -22.857 33.099 -7.811 1.00 42.31 ? 301 ARG B NH1 1 ATOM 2145 N NH2 . ARG B 2 94 ? -22.523 30.908 -7.223 1.00 47.77 ? 301 ARG B NH2 1 ATOM 2146 N N . VAL B 2 95 ? -25.614 32.763 -13.954 1.00 38.71 ? 302 VAL B N 1 ATOM 2147 C CA . VAL B 2 95 ? -27.013 33.171 -13.813 1.00 34.50 ? 302 VAL B CA 1 ATOM 2148 C C . VAL B 2 95 ? -27.638 32.479 -12.591 1.00 37.61 ? 302 VAL B C 1 ATOM 2149 O O . VAL B 2 95 ? -27.649 31.248 -12.510 1.00 40.11 ? 302 VAL B O 1 ATOM 2150 C CB . VAL B 2 95 ? -27.847 32.809 -15.066 1.00 38.56 ? 302 VAL B CB 1 ATOM 2151 C CG1 . VAL B 2 95 ? -29.291 33.265 -14.891 1.00 38.58 ? 302 VAL B CG1 1 ATOM 2152 C CG2 . VAL B 2 95 ? -27.252 33.397 -16.351 1.00 27.38 ? 302 VAL B CG2 1 ATOM 2153 N N . VAL B 2 96 ? -28.163 33.270 -11.660 1.00 32.40 ? 303 VAL B N 1 ATOM 2154 C CA . VAL B 2 96 ? -28.704 32.763 -10.390 1.00 34.63 ? 303 VAL B CA 1 ATOM 2155 C C . VAL B 2 96 ? -30.202 33.084 -10.241 1.00 35.52 ? 303 VAL B C 1 ATOM 2156 O O . VAL B 2 96 ? -30.644 34.184 -10.582 1.00 39.52 ? 303 VAL B O 1 ATOM 2157 C CB . VAL B 2 96 ? -27.920 33.331 -9.174 1.00 32.70 ? 303 VAL B CB 1 ATOM 2158 C CG1 . VAL B 2 96 ? -28.438 32.769 -7.858 1.00 29.75 ? 303 VAL B CG1 1 ATOM 2159 C CG2 . VAL B 2 96 ? -26.434 33.045 -9.298 1.00 34.20 ? 303 VAL B CG2 1 ATOM 2160 N N . SER B 2 97 ? -30.968 32.114 -9.737 1.00 34.53 ? 304 SER B N 1 ATOM 2161 C CA . SER B 2 97 ? -32.400 32.278 -9.450 1.00 30.73 ? 304 SER B CA 1 ATOM 2162 C C . SER B 2 97 ? -32.696 31.883 -8.005 1.00 31.94 ? 304 SER B C 1 ATOM 2163 O O . SER B 2 97 ? -32.451 30.749 -7.609 1.00 32.80 ? 304 SER B O 1 ATOM 2164 C CB . SER B 2 97 ? -33.233 31.423 -10.394 1.00 30.62 ? 304 SER B CB 1 ATOM 2165 O OG . SER B 2 97 ? -34.605 31.443 -10.027 1.00 30.08 ? 304 SER B OG 1 ATOM 2166 N N . VAL B 2 98 ? -33.216 32.824 -7.225 1.00 35.36 ? 305 VAL B N 1 ATOM 2167 C CA . VAL B 2 98 ? -33.477 32.598 -5.811 1.00 34.86 ? 305 VAL B CA 1 ATOM 2168 C C . VAL B 2 98 ? -34.978 32.471 -5.525 1.00 40.04 ? 305 VAL B C 1 ATOM 2169 O O . VAL B 2 98 ? -35.766 33.365 -5.856 1.00 47.88 ? 305 VAL B O 1 ATOM 2170 C CB . VAL B 2 98 ? -32.878 33.717 -4.942 1.00 36.41 ? 305 VAL B CB 1 ATOM 2171 C CG1 . VAL B 2 98 ? -33.188 33.466 -3.480 1.00 31.73 ? 305 VAL B CG1 1 ATOM 2172 C CG2 . VAL B 2 98 ? -31.370 33.809 -5.137 1.00 36.68 ? 305 VAL B CG2 1 ATOM 2173 N N . LEU B 2 99 ? -35.362 31.351 -4.915 1.00 37.12 ? 306 LEU B N 1 ATOM 2174 C CA . LEU B 2 99 ? -36.750 31.113 -4.527 1.00 33.29 ? 306 LEU B CA 1 ATOM 2175 C C . LEU B 2 99 ? -36.887 31.085 -3.012 1.00 29.80 ? 306 LEU B C 1 ATOM 2176 O O . LEU B 2 99 ? -36.380 30.174 -2.361 1.00 27.56 ? 306 LEU B O 1 ATOM 2177 C CB . LEU B 2 99 ? -37.269 29.793 -5.103 1.00 23.94 ? 306 LEU B CB 1 ATOM 2178 C CG . LEU B 2 99 ? -38.768 29.523 -4.826 1.00 25.01 ? 306 LEU B CG 1 ATOM 2179 C CD1 . LEU B 2 99 ? -39.670 30.166 -5.860 1.00 23.73 ? 306 LEU B CD1 1 ATOM 2180 C CD2 . LEU B 2 99 ? -39.040 28.029 -4.744 1.00 21.87 ? 306 LEU B CD2 1 ATOM 2181 N N . THR B 2 100 ? -37.582 32.070 -2.458 1.00 31.07 ? 307 THR B N 1 ATOM 2182 C CA . THR B 2 100 ? -37.939 32.029 -1.046 1.00 38.84 ? 307 THR B CA 1 ATOM 2183 C C . THR B 2 100 ? -38.868 30.837 -0.800 1.00 39.37 ? 307 THR B C 1 ATOM 2184 O O . THR B 2 100 ? -39.661 30.453 -1.668 1.00 37.86 ? 307 THR B O 1 ATOM 2185 C CB . THR B 2 100 ? -38.598 33.341 -0.593 1.00 41.23 ? 307 THR B CB 1 ATOM 2186 O OG1 . THR B 2 100 ? -37.762 34.435 -0.978 1.00 43.79 ? 307 THR B OG1 1 ATOM 2187 C CG2 . THR B 2 100 ? -38.764 33.372 0.921 1.00 45.35 ? 307 THR B CG2 1 ATOM 2188 N N . VAL B 2 101 ? -38.710 30.212 0.358 1.00 32.37 ? 308 VAL B N 1 ATOM 2189 C CA . VAL B 2 101 ? -39.571 29.117 0.764 1.00 32.57 ? 308 VAL B CA 1 ATOM 2190 C C . VAL B 2 101 ? -40.069 29.470 2.159 1.00 39.28 ? 308 VAL B C 1 ATOM 2191 O O . VAL B 2 101 ? -39.392 30.200 2.886 1.00 30.61 ? 308 VAL B O 1 ATOM 2192 C CB . VAL B 2 101 ? -38.834 27.751 0.776 1.00 34.17 ? 308 VAL B CB 1 ATOM 2193 C CG1 . VAL B 2 101 ? -38.200 27.460 -0.577 1.00 30.12 ? 308 VAL B CG1 1 ATOM 2194 C CG2 . VAL B 2 101 ? -37.786 27.670 1.896 1.00 28.93 ? 308 VAL B CG2 1 ATOM 2195 N N . LEU B 2 102 ? -41.248 28.975 2.523 1.00 40.51 ? 309 LEU B N 1 ATOM 2196 C CA . LEU B 2 102 ? -41.708 29.097 3.899 1.00 43.04 ? 309 LEU B CA 1 ATOM 2197 C C . LEU B 2 102 ? -40.967 28.073 4.740 1.00 37.47 ? 309 LEU B C 1 ATOM 2198 O O . LEU B 2 102 ? -40.639 26.989 4.253 1.00 37.69 ? 309 LEU B O 1 ATOM 2199 C CB . LEU B 2 102 ? -43.223 28.889 4.007 1.00 47.01 ? 309 LEU B CB 1 ATOM 2200 C CG . LEU B 2 102 ? -44.202 29.947 3.465 1.00 47.67 ? 309 LEU B CG 1 ATOM 2201 C CD1 . LEU B 2 102 ? -45.491 29.926 4.282 1.00 38.08 ? 309 LEU B CD1 1 ATOM 2202 C CD2 . LEU B 2 102 ? -43.620 31.356 3.465 1.00 42.19 ? 309 LEU B CD2 1 ATOM 2203 N N . HIS B 2 103 ? -40.694 28.424 5.995 1.00 42.71 ? 310 HIS B N 1 ATOM 2204 C CA . HIS B 2 103 ? -40.003 27.525 6.923 1.00 42.27 ? 310 HIS B CA 1 ATOM 2205 C C . HIS B 2 103 ? -40.651 26.165 6.981 1.00 40.96 ? 310 HIS B C 1 ATOM 2206 O O . HIS B 2 103 ? -39.988 25.143 6.769 1.00 39.20 ? 310 HIS B O 1 ATOM 2207 C CB . HIS B 2 103 ? -39.957 28.124 8.322 1.00 41.21 ? 310 HIS B CB 1 ATOM 2208 C CG . HIS B 2 103 ? -39.320 29.489 8.384 1.00 50.70 ? 310 HIS B CG 1 ATOM 2209 N ND1 . HIS B 2 103 ? -39.968 30.607 8.016 1.00 54.82 ? 310 HIS B ND1 1 ATOM 2210 C CD2 . HIS B 2 103 ? -38.055 29.888 8.803 1.00 52.08 ? 310 HIS B CD2 1 ATOM 2211 C CE1 . HIS B 2 103 ? -39.159 31.668 8.185 1.00 50.56 ? 310 HIS B CE1 1 ATOM 2212 N NE2 . HIS B 2 103 ? -37.990 31.226 8.668 1.00 56.14 ? 310 HIS B NE2 1 ATOM 2213 N N . GLN B 2 104 ? -41.960 26.150 7.243 1.00 34.66 ? 311 GLN B N 1 ATOM 2214 C CA . GLN B 2 104 ? -42.689 24.907 7.490 1.00 31.26 ? 311 GLN B CA 1 ATOM 2215 C C . GLN B 2 104 ? -42.673 23.997 6.261 1.00 36.55 ? 311 GLN B C 1 ATOM 2216 O O . GLN B 2 104 ? -42.591 22.784 6.407 1.00 45.35 ? 311 GLN B O 1 ATOM 2217 C CB . GLN B 2 104 ? -44.119 25.195 7.963 1.00 26.64 ? 311 GLN B CB 1 ATOM 2218 N N . ASP B 2 105 ? -42.714 24.590 5.063 1.00 33.37 ? 312 ASP B N 1 ATOM 2219 C CA . ASP B 2 105 ? -42.607 23.847 3.789 1.00 35.31 ? 312 ASP B CA 1 ATOM 2220 C C . ASP B 2 105 ? -41.305 23.053 3.642 1.00 37.16 ? 312 ASP B C 1 ATOM 2221 O O . ASP B 2 105 ? -41.328 21.855 3.318 1.00 40.24 ? 312 ASP B O 1 ATOM 2222 C CB . ASP B 2 105 ? -42.732 24.802 2.593 1.00 39.61 ? 312 ASP B CB 1 ATOM 2223 C CG . ASP B 2 105 ? -44.136 25.350 2.411 1.00 48.27 ? 312 ASP B CG 1 ATOM 2224 O OD1 . ASP B 2 105 ? -45.118 24.633 2.708 1.00 48.01 ? 312 ASP B OD1 1 ATOM 2225 O OD2 . ASP B 2 105 ? -44.257 26.505 1.952 1.00 54.75 ? 312 ASP B OD2 1 ATOM 2226 N N . TRP B 2 106 ? -40.173 23.727 3.856 1.00 39.21 ? 313 TRP B N 1 ATOM 2227 C CA . TRP B 2 106 ? -38.866 23.076 3.783 1.00 37.36 ? 313 TRP B CA 1 ATOM 2228 C C . TRP B 2 106 ? -38.750 22.000 4.819 1.00 37.97 ? 313 TRP B C 1 ATOM 2229 O O . TRP B 2 106 ? -38.417 20.854 4.493 1.00 34.15 ? 313 TRP B O 1 ATOM 2230 C CB . TRP B 2 106 ? -37.718 24.081 3.945 1.00 41.84 ? 313 TRP B CB 1 ATOM 2231 C CG . TRP B 2 106 ? -36.367 23.408 3.872 1.00 37.69 ? 313 TRP B CG 1 ATOM 2232 C CD1 . TRP B 2 106 ? -35.570 22.985 4.927 1.00 33.60 ? 313 TRP B CD1 1 ATOM 2233 C CD2 . TRP B 2 106 ? -35.640 23.005 2.661 1.00 38.01 ? 313 TRP B CD2 1 ATOM 2234 N NE1 . TRP B 2 106 ? -34.421 22.389 4.466 1.00 36.36 ? 313 TRP B NE1 1 ATOM 2235 C CE2 . TRP B 2 106 ? -34.403 22.363 3.120 1.00 39.14 ? 313 TRP B CE2 1 ATOM 2236 C CE3 . TRP B 2 106 ? -35.875 23.120 1.297 1.00 34.78 ? 313 TRP B CE3 1 ATOM 2237 C CZ2 . TRP B 2 106 ? -33.461 21.865 2.234 1.00 36.99 ? 313 TRP B CZ2 1 ATOM 2238 C CZ3 . TRP B 2 106 ? -34.921 22.612 0.414 1.00 36.45 ? 313 TRP B CZ3 1 ATOM 2239 C CH2 . TRP B 2 106 ? -33.741 22.006 0.871 1.00 38.96 ? 313 TRP B CH2 1 ATOM 2240 N N . LEU B 2 107 ? -39.017 22.364 6.076 1.00 34.64 ? 314 LEU B N 1 ATOM 2241 C CA . LEU B 2 107 ? -38.927 21.426 7.203 1.00 39.95 ? 314 LEU B CA 1 ATOM 2242 C C . LEU B 2 107 ? -39.874 20.218 7.093 1.00 44.48 ? 314 LEU B C 1 ATOM 2243 O O . LEU B 2 107 ? -39.596 19.159 7.656 1.00 46.14 ? 314 LEU B O 1 ATOM 2244 C CB . LEU B 2 107 ? -39.149 22.155 8.543 1.00 39.72 ? 314 LEU B CB 1 ATOM 2245 C CG . LEU B 2 107 ? -38.148 23.247 8.965 1.00 41.80 ? 314 LEU B CG 1 ATOM 2246 C CD1 . LEU B 2 107 ? -38.471 23.791 10.353 1.00 42.75 ? 314 LEU B CD1 1 ATOM 2247 C CD2 . LEU B 2 107 ? -36.710 22.749 8.912 1.00 41.04 ? 314 LEU B CD2 1 ATOM 2248 N N . ASN B 2 108 ? -40.983 20.377 6.371 1.00 51.01 ? 315 ASN B N 1 ATOM 2249 C CA . ASN B 2 108 ? -41.929 19.274 6.163 1.00 50.30 ? 315 ASN B CA 1 ATOM 2250 C C . ASN B 2 108 ? -41.611 18.410 4.947 1.00 46.09 ? 315 ASN B C 1 ATOM 2251 O O . ASN B 2 108 ? -42.390 17.530 4.588 1.00 50.52 ? 315 ASN B O 1 ATOM 2252 C CB . ASN B 2 108 ? -43.378 19.776 6.117 1.00 48.04 ? 315 ASN B CB 1 ATOM 2253 C CG . ASN B 2 108 ? -43.887 20.208 7.481 1.00 51.30 ? 315 ASN B CG 1 ATOM 2254 O OD1 . ASN B 2 108 ? -43.627 19.550 8.488 1.00 52.61 ? 315 ASN B OD1 1 ATOM 2255 N ND2 . ASN B 2 108 ? -44.620 21.314 7.520 1.00 50.77 ? 315 ASN B ND2 1 ATOM 2256 N N . GLY B 2 109 ? -40.474 18.673 4.313 1.00 41.04 ? 316 GLY B N 1 ATOM 2257 C CA . GLY B 2 109 ? -39.939 17.772 3.302 1.00 33.51 ? 316 GLY B CA 1 ATOM 2258 C C . GLY B 2 109 ? -40.337 18.024 1.864 1.00 31.84 ? 316 GLY B C 1 ATOM 2259 O O . GLY B 2 109 ? -40.174 17.152 1.014 1.00 34.47 ? 316 GLY B O 1 ATOM 2260 N N . LYS B 2 110 ? -40.829 19.217 1.571 1.00 38.16 ? 317 LYS B N 1 ATOM 2261 C CA . LYS B 2 110 ? -41.276 19.532 0.215 1.00 34.59 ? 317 LYS B CA 1 ATOM 2262 C C . LYS B 2 110 ? -40.116 19.508 -0.788 1.00 39.98 ? 317 LYS B C 1 ATOM 2263 O O . LYS B 2 110 ? -38.982 19.854 -0.452 1.00 35.85 ? 317 LYS B O 1 ATOM 2264 C CB . LYS B 2 110 ? -42.032 20.864 0.191 1.00 33.87 ? 317 LYS B CB 1 ATOM 2265 C CG . LYS B 2 110 ? -43.387 20.798 0.889 1.00 45.19 ? 317 LYS B CG 1 ATOM 2266 C CD . LYS B 2 110 ? -44.220 22.046 0.638 1.00 56.25 ? 317 LYS B CD 1 ATOM 2267 C CE . LYS B 2 110 ? -45.652 21.882 1.136 1.00 60.22 ? 317 LYS B CE 1 ATOM 2268 N NZ . LYS B 2 110 ? -46.469 21.009 0.249 1.00 65.02 ? 317 LYS B NZ 1 ATOM 2269 N N . GLU B 2 111 ? -40.413 19.073 -2.010 1.00 41.80 ? 318 GLU B N 1 ATOM 2270 C CA . GLU B 2 111 ? -39.411 18.898 -3.053 1.00 41.13 ? 318 GLU B CA 1 ATOM 2271 C C . GLU B 2 111 ? -39.350 20.132 -3.929 1.00 42.17 ? 318 GLU B C 1 ATOM 2272 O O . GLU B 2 111 ? -40.371 20.579 -4.447 1.00 37.22 ? 318 GLU B O 1 ATOM 2273 C CB . GLU B 2 111 ? -39.752 17.687 -3.924 1.00 54.54 ? 318 GLU B CB 1 ATOM 2274 C CG . GLU B 2 111 ? -39.667 16.345 -3.215 1.00 64.14 ? 318 GLU B CG 1 ATOM 2275 C CD . GLU B 2 111 ? -38.256 15.798 -3.166 1.00 72.06 ? 318 GLU B CD 1 ATOM 2276 O OE1 . GLU B 2 111 ? -37.543 15.887 -4.188 1.00 72.39 ? 318 GLU B OE1 1 ATOM 2277 O OE2 . GLU B 2 111 ? -37.865 15.269 -2.105 1.00 80.46 ? 318 GLU B OE2 1 ATOM 2278 N N . TYR B 2 112 ? -38.150 20.680 -4.102 1.00 38.65 ? 319 TYR B N 1 ATOM 2279 C CA . TYR B 2 112 ? -37.985 21.877 -4.921 1.00 31.08 ? 319 TYR B CA 1 ATOM 2280 C C . TYR B 2 112 ? -37.197 21.567 -6.173 1.00 32.37 ? 319 TYR B C 1 ATOM 2281 O O . TYR B 2 112 ? -36.040 21.158 -6.094 1.00 36.83 ? 319 TYR B O 1 ATOM 2282 C CB . TYR B 2 112 ? -37.324 22.985 -4.125 1.00 28.17 ? 319 TYR B CB 1 ATOM 2283 C CG . TYR B 2 112 ? -38.144 23.389 -2.931 1.00 29.39 ? 319 TYR B CG 1 ATOM 2284 C CD1 . TYR B 2 112 ? -38.055 22.686 -1.734 1.00 29.43 ? 319 TYR B CD1 1 ATOM 2285 C CD2 . TYR B 2 112 ? -39.014 24.478 -2.995 1.00 28.24 ? 319 TYR B CD2 1 ATOM 2286 C CE1 . TYR B 2 112 ? -38.811 23.049 -0.631 1.00 30.46 ? 319 TYR B CE1 1 ATOM 2287 C CE2 . TYR B 2 112 ? -39.779 24.840 -1.904 1.00 29.60 ? 319 TYR B CE2 1 ATOM 2288 C CZ . TYR B 2 112 ? -39.667 24.123 -0.724 1.00 30.95 ? 319 TYR B CZ 1 ATOM 2289 O OH . TYR B 2 112 ? -40.410 24.480 0.370 1.00 43.80 ? 319 TYR B OH 1 ATOM 2290 N N . LYS B 2 113 ? -37.840 21.755 -7.322 1.00 32.43 ? 320 LYS B N 1 ATOM 2291 C CA . LYS B 2 113 ? -37.228 21.476 -8.614 1.00 35.53 ? 320 LYS B CA 1 ATOM 2292 C C . LYS B 2 113 ? -36.926 22.775 -9.365 1.00 36.90 ? 320 LYS B C 1 ATOM 2293 O O . LYS B 2 113 ? -37.779 23.655 -9.473 1.00 37.45 ? 320 LYS B O 1 ATOM 2294 C CB . LYS B 2 113 ? -38.124 20.554 -9.456 1.00 33.22 ? 320 LYS B CB 1 ATOM 2295 C CG . LYS B 2 113 ? -37.531 20.171 -10.812 1.00 38.34 ? 320 LYS B CG 1 ATOM 2296 C CD . LYS B 2 113 ? -38.552 19.567 -11.773 1.00 45.44 ? 320 LYS B CD 1 ATOM 2297 C CE . LYS B 2 113 ? -38.807 18.087 -11.507 1.00 51.01 ? 320 LYS B CE 1 ATOM 2298 N NZ . LYS B 2 113 ? -39.635 17.449 -12.578 1.00 47.13 ? 320 LYS B NZ 1 ATOM 2299 N N . CYS B 2 114 ? -35.695 22.886 -9.856 1.00 38.09 ? 321 CYS B N 1 ATOM 2300 C CA . CYS B 2 114 ? -35.290 23.953 -10.753 1.00 38.48 ? 321 CYS B CA 1 ATOM 2301 C C . CYS B 2 114 ? -35.145 23.334 -12.145 1.00 45.03 ? 321 CYS B C 1 ATOM 2302 O O . CYS B 2 114 ? -34.407 22.360 -12.311 1.00 43.27 ? 321 CYS B O 1 ATOM 2303 C CB . CYS B 2 114 ? -33.950 24.546 -10.293 1.00 41.27 ? 321 CYS B CB 1 ATOM 2304 S SG . CYS B 2 114 ? -33.359 25.921 -11.306 1.00 58.39 ? 321 CYS B SG 1 ATOM 2305 N N . LYS B 2 115 ? -35.867 23.872 -13.128 1.00 46.99 ? 322 LYS B N 1 ATOM 2306 C CA . LYS B 2 115 ? -35.680 23.488 -14.527 1.00 44.33 ? 322 LYS B CA 1 ATOM 2307 C C . LYS B 2 115 ? -35.110 24.651 -15.326 1.00 48.72 ? 322 LYS B C 1 ATOM 2308 O O . LYS B 2 115 ? -35.661 25.752 -15.333 1.00 46.58 ? 322 LYS B O 1 ATOM 2309 C CB . LYS B 2 115 ? -36.969 22.985 -15.176 1.00 46.41 ? 322 LYS B CB 1 ATOM 2310 C CG . LYS B 2 115 ? -36.747 22.522 -16.613 1.00 53.69 ? 322 LYS B CG 1 ATOM 2311 C CD . LYS B 2 115 ? -37.922 21.748 -17.186 1.00 59.89 ? 322 LYS B CD 1 ATOM 2312 C CE . LYS B 2 115 ? -38.842 22.646 -17.991 1.00 60.92 ? 322 LYS B CE 1 ATOM 2313 N NZ . LYS B 2 115 ? -39.889 21.851 -18.686 1.00 69.23 ? 322 LYS B NZ 1 ATOM 2314 N N . VAL B 2 116 ? -34.002 24.385 -16.005 1.00 43.42 ? 323 VAL B N 1 ATOM 2315 C CA . VAL B 2 116 ? -33.238 25.420 -16.656 1.00 40.30 ? 323 VAL B CA 1 ATOM 2316 C C . VAL B 2 116 ? -33.234 25.157 -18.162 1.00 46.98 ? 323 VAL B C 1 ATOM 2317 O O . VAL B 2 116 ? -32.705 24.150 -18.619 1.00 49.35 ? 323 VAL B O 1 ATOM 2318 C CB . VAL B 2 116 ? -31.799 25.462 -16.092 1.00 34.40 ? 323 VAL B CB 1 ATOM 2319 C CG1 . VAL B 2 116 ? -30.940 26.452 -16.856 1.00 35.06 ? 323 VAL B CG1 1 ATOM 2320 C CG2 . VAL B 2 116 ? -31.805 25.803 -14.608 1.00 38.36 ? 323 VAL B CG2 1 ATOM 2321 N N . SER B 2 117 ? -33.852 26.051 -18.926 1.00 46.31 ? 324 SER B N 1 ATOM 2322 C CA . SER B 2 117 ? -33.822 25.951 -20.382 1.00 48.27 ? 324 SER B CA 1 ATOM 2323 C C . SER B 2 117 ? -32.841 26.964 -20.966 1.00 49.63 ? 324 SER B C 1 ATOM 2324 O O . SER B 2 117 ? -32.650 28.049 -20.409 1.00 52.09 ? 324 SER B O 1 ATOM 2325 C CB . SER B 2 117 ? -35.216 26.162 -20.973 1.00 50.98 ? 324 SER B CB 1 ATOM 2326 O OG . SER B 2 117 ? -36.066 25.068 -20.688 1.00 56.11 ? 324 SER B OG 1 ATOM 2327 N N . ASN B 2 118 ? -32.222 26.596 -22.085 1.00 53.48 ? 325 ASN B N 1 ATOM 2328 C CA . ASN B 2 118 ? -31.224 27.431 -22.756 1.00 57.22 ? 325 ASN B CA 1 ATOM 2329 C C . ASN B 2 118 ? -31.038 26.969 -24.199 1.00 56.81 ? 325 ASN B C 1 ATOM 2330 O O . ASN B 2 118 ? -31.135 25.776 -24.483 1.00 55.95 ? 325 ASN B O 1 ATOM 2331 C CB . ASN B 2 118 ? -29.891 27.371 -21.994 1.00 59.83 ? 325 ASN B CB 1 ATOM 2332 C CG . ASN B 2 118 ? -28.771 28.114 -22.698 1.00 60.27 ? 325 ASN B CG 1 ATOM 2333 O OD1 . ASN B 2 118 ? -27.758 27.521 -23.056 1.00 76.45 ? 325 ASN B OD1 1 ATOM 2334 N ND2 . ASN B 2 118 ? -28.947 29.414 -22.897 1.00 60.12 ? 325 ASN B ND2 1 ATOM 2335 N N . LYS B 2 119 ? -30.771 27.913 -25.102 1.00 65.07 ? 326 LYS B N 1 ATOM 2336 C CA . LYS B 2 119 ? -30.573 27.597 -26.525 1.00 74.37 ? 326 LYS B CA 1 ATOM 2337 C C . LYS B 2 119 ? -29.352 26.700 -26.786 1.00 73.07 ? 326 LYS B C 1 ATOM 2338 O O . LYS B 2 119 ? -29.356 25.910 -27.731 1.00 72.45 ? 326 LYS B O 1 ATOM 2339 C CB . LYS B 2 119 ? -30.494 28.875 -27.368 1.00 63.65 ? 326 LYS B CB 1 ATOM 2340 N N . ALA B 2 120 ? -28.326 26.821 -25.942 1.00 69.55 ? 327 ALA B N 1 ATOM 2341 C CA . ALA B 2 120 ? -27.100 26.019 -26.057 1.00 70.08 ? 327 ALA B CA 1 ATOM 2342 C C . ALA B 2 120 ? -27.183 24.727 -25.233 1.00 66.75 ? 327 ALA B C 1 ATOM 2343 O O . ALA B 2 120 ? -26.232 24.350 -24.542 1.00 64.61 ? 327 ALA B O 1 ATOM 2344 C CB . ALA B 2 120 ? -25.888 26.847 -25.642 1.00 62.43 ? 327 ALA B CB 1 ATOM 2345 N N . LEU B 2 121 ? -28.328 24.052 -25.325 1.00 64.55 ? 328 LEU B N 1 ATOM 2346 C CA . LEU B 2 121 ? -28.634 22.902 -24.481 1.00 61.18 ? 328 LEU B CA 1 ATOM 2347 C C . LEU B 2 121 ? -29.631 22.012 -25.216 1.00 62.53 ? 328 LEU B C 1 ATOM 2348 O O . LEU B 2 121 ? -30.759 22.438 -25.474 1.00 70.70 ? 328 LEU B O 1 ATOM 2349 C CB . LEU B 2 121 ? -29.220 23.383 -23.147 1.00 58.09 ? 328 LEU B CB 1 ATOM 2350 C CG . LEU B 2 121 ? -28.904 22.666 -21.834 1.00 58.54 ? 328 LEU B CG 1 ATOM 2351 C CD1 . LEU B 2 121 ? -27.468 22.911 -21.403 1.00 60.53 ? 328 LEU B CD1 1 ATOM 2352 C CD2 . LEU B 2 121 ? -29.856 23.156 -20.757 1.00 59.95 ? 328 LEU B CD2 1 ATOM 2353 N N . PRO B 2 122 ? -29.218 20.778 -25.572 1.00 63.18 ? 329 PRO B N 1 ATOM 2354 C CA . PRO B 2 122 ? -30.045 19.866 -26.375 1.00 70.77 ? 329 PRO B CA 1 ATOM 2355 C C . PRO B 2 122 ? -31.437 19.626 -25.779 1.00 73.49 ? 329 PRO B C 1 ATOM 2356 O O . PRO B 2 122 ? -32.419 19.497 -26.522 1.00 66.91 ? 329 PRO B O 1 ATOM 2357 C CB . PRO B 2 122 ? -29.224 18.574 -26.389 1.00 70.71 ? 329 PRO B CB 1 ATOM 2358 C CG . PRO B 2 122 ? -27.817 19.035 -26.222 1.00 65.18 ? 329 PRO B CG 1 ATOM 2359 C CD . PRO B 2 122 ? -27.906 20.182 -25.258 1.00 64.80 ? 329 PRO B CD 1 ATOM 2360 N N . ALA B 2 123 ? -31.502 19.560 -24.450 1.00 68.63 ? 330 ALA B N 1 ATOM 2361 C CA . ALA B 2 123 ? -32.764 19.533 -23.709 1.00 59.17 ? 330 ALA B CA 1 ATOM 2362 C C . ALA B 2 123 ? -32.536 20.183 -22.337 1.00 51.15 ? 330 ALA B C 1 ATOM 2363 O O . ALA B 2 123 ? -31.399 20.226 -21.862 1.00 60.95 ? 330 ALA B O 1 ATOM 2364 C CB . ALA B 2 123 ? -33.285 18.105 -23.573 1.00 53.09 ? 330 ALA B CB 1 ATOM 2365 N N . PRO B 2 124 ? -33.605 20.707 -21.706 1.00 45.75 ? 331 PRO B N 1 ATOM 2366 C CA . PRO B 2 124 ? -33.449 21.425 -20.434 1.00 50.46 ? 331 PRO B CA 1 ATOM 2367 C C . PRO B 2 124 ? -32.939 20.566 -19.263 1.00 48.83 ? 331 PRO B C 1 ATOM 2368 O O . PRO B 2 124 ? -33.304 19.399 -19.150 1.00 54.21 ? 331 PRO B O 1 ATOM 2369 C CB . PRO B 2 124 ? -34.871 21.936 -20.142 1.00 52.28 ? 331 PRO B CB 1 ATOM 2370 C CG . PRO B 2 124 ? -35.577 21.918 -21.457 1.00 47.21 ? 331 PRO B CG 1 ATOM 2371 C CD . PRO B 2 124 ? -35.006 20.730 -22.171 1.00 48.93 ? 331 PRO B CD 1 ATOM 2372 N N . ILE B 2 125 ? -32.111 21.161 -18.403 1.00 49.02 ? 332 ILE B N 1 ATOM 2373 C CA . ILE B 2 125 ? -31.536 20.480 -17.238 1.00 52.80 ? 332 ILE B CA 1 ATOM 2374 C C . ILE B 2 125 ? -32.389 20.702 -15.991 1.00 57.14 ? 332 ILE B C 1 ATOM 2375 O O . ILE B 2 125 ? -32.675 21.842 -15.616 1.00 52.25 ? 332 ILE B O 1 ATOM 2376 C CB . ILE B 2 125 ? -30.093 20.958 -16.945 1.00 49.28 ? 332 ILE B CB 1 ATOM 2377 C CG1 . ILE B 2 125 ? -29.169 20.650 -18.130 1.00 56.16 ? 332 ILE B CG1 1 ATOM 2378 C CG2 . ILE B 2 125 ? -29.559 20.336 -15.657 1.00 39.77 ? 332 ILE B CG2 1 ATOM 2379 C CD1 . ILE B 2 125 ? -27.820 21.347 -18.078 1.00 58.99 ? 332 ILE B CD1 1 ATOM 2380 N N . GLU B 2 126 ? -32.772 19.602 -15.349 1.00 57.76 ? 333 GLU B N 1 ATOM 2381 C CA . GLU B 2 126 ? -33.578 19.645 -14.130 1.00 54.92 ? 333 GLU B CA 1 ATOM 2382 C C . GLU B 2 126 ? -32.765 19.154 -12.941 1.00 54.46 ? 333 GLU B C 1 ATOM 2383 O O . GLU B 2 126 ? -32.017 18.181 -13.054 1.00 63.68 ? 333 GLU B O 1 ATOM 2384 C CB . GLU B 2 126 ? -34.850 18.800 -14.288 1.00 59.14 ? 333 GLU B CB 1 ATOM 2385 C CG . GLU B 2 126 ? -35.653 19.102 -15.552 1.00 67.13 ? 333 GLU B CG 1 ATOM 2386 C CD . GLU B 2 126 ? -37.049 18.492 -15.556 1.00 73.24 ? 333 GLU B CD 1 ATOM 2387 O OE1 . GLU B 2 126 ? -37.660 18.420 -16.644 1.00 73.67 ? 333 GLU B OE1 1 ATOM 2388 O OE2 . GLU B 2 126 ? -37.545 18.093 -14.481 1.00 66.03 ? 333 GLU B OE2 1 ATOM 2389 N N . LYS B 2 127 ? -32.897 19.846 -11.813 1.00 46.19 ? 334 LYS B N 1 ATOM 2390 C CA . LYS B 2 127 ? -32.262 19.440 -10.559 1.00 45.59 ? 334 LYS B CA 1 ATOM 2391 C C . LYS B 2 127 ? -33.290 19.548 -9.447 1.00 49.44 ? 334 LYS B C 1 ATOM 2392 O O . LYS B 2 127 ? -34.198 20.372 -9.523 1.00 63.64 ? 334 LYS B O 1 ATOM 2393 C CB . LYS B 2 127 ? -31.062 20.335 -10.234 1.00 43.58 ? 334 LYS B CB 1 ATOM 2394 C CG . LYS B 2 127 ? -29.917 20.266 -11.234 1.00 46.72 ? 334 LYS B CG 1 ATOM 2395 C CD . LYS B 2 127 ? -28.941 19.137 -10.932 1.00 47.87 ? 334 LYS B CD 1 ATOM 2396 C CE . LYS B 2 127 ? -28.126 18.799 -12.170 1.00 48.71 ? 334 LYS B CE 1 ATOM 2397 N NZ . LYS B 2 127 ? -26.890 18.038 -11.844 1.00 48.94 ? 334 LYS B NZ 1 ATOM 2398 N N . THR B 2 128 ? -33.141 18.728 -8.413 1.00 46.46 ? 335 THR B N 1 ATOM 2399 C CA . THR B 2 128 ? -34.091 18.693 -7.305 1.00 41.02 ? 335 THR B CA 1 ATOM 2400 C C . THR B 2 128 ? -33.342 18.591 -5.988 1.00 38.85 ? 335 THR B C 1 ATOM 2401 O O . THR B 2 128 ? -32.300 17.952 -5.916 1.00 46.20 ? 335 THR B O 1 ATOM 2402 C CB . THR B 2 128 ? -35.050 17.479 -7.422 1.00 47.04 ? 335 THR B CB 1 ATOM 2403 O OG1 . THR B 2 128 ? -35.553 17.373 -8.764 1.00 43.00 ? 335 THR B OG1 1 ATOM 2404 C CG2 . THR B 2 128 ? -36.225 17.611 -6.450 1.00 39.09 ? 335 THR B CG2 1 ATOM 2405 N N . ILE B 2 129 ? -33.877 19.229 -4.952 1.00 42.01 ? 336 ILE B N 1 ATOM 2406 C CA . ILE B 2 129 ? -33.376 19.074 -3.589 1.00 42.47 ? 336 ILE B CA 1 ATOM 2407 C C . ILE B 2 129 ? -34.521 19.142 -2.592 1.00 44.06 ? 336 ILE B C 1 ATOM 2408 O O . ILE B 2 129 ? -35.580 19.703 -2.881 1.00 41.90 ? 336 ILE B O 1 ATOM 2409 C CB . ILE B 2 129 ? -32.302 20.130 -3.190 1.00 49.51 ? 336 ILE B CB 1 ATOM 2410 C CG1 . ILE B 2 129 ? -32.692 21.538 -3.649 1.00 48.06 ? 336 ILE B CG1 1 ATOM 2411 C CG2 . ILE B 2 129 ? -30.916 19.751 -3.703 1.00 49.60 ? 336 ILE B CG2 1 ATOM 2412 C CD1 . ILE B 2 129 ? -33.448 22.341 -2.620 1.00 50.01 ? 336 ILE B CD1 1 ATOM 2413 N N . SER B 2 130 ? -34.284 18.573 -1.415 1.00 35.87 ? 337 SER B N 1 ATOM 2414 C CA . SER B 2 130 ? -35.183 18.707 -0.280 1.00 33.26 ? 337 SER B CA 1 ATOM 2415 C C . SER B 2 130 ? -34.361 18.523 0.977 1.00 28.31 ? 337 SER B C 1 ATOM 2416 O O . SER B 2 130 ? -33.165 18.259 0.906 1.00 34.36 ? 337 SER B O 1 ATOM 2417 C CB . SER B 2 130 ? -36.293 17.653 -0.334 1.00 38.28 ? 337 SER B CB 1 ATOM 2418 O OG . SER B 2 130 ? -35.757 16.341 -0.307 1.00 43.31 ? 337 SER B OG 1 ATOM 2419 N N . LYS B 2 131 ? -34.998 18.676 2.129 1.00 33.12 ? 338 LYS B N 1 ATOM 2420 C CA . LYS B 2 131 ? -34.384 18.327 3.404 1.00 29.29 ? 338 LYS B CA 1 ATOM 2421 C C . LYS B 2 131 ? -33.997 16.847 3.361 1.00 41.43 ? 338 LYS B C 1 ATOM 2422 O O . LYS B 2 131 ? -34.586 16.066 2.591 1.00 46.39 ? 338 LYS B O 1 ATOM 2423 C CB . LYS B 2 131 ? -35.388 18.572 4.522 1.00 33.40 ? 338 LYS B CB 1 ATOM 2424 C CG . LYS B 2 131 ? -34.790 18.616 5.922 1.00 38.25 ? 338 LYS B CG 1 ATOM 2425 C CD . LYS B 2 131 ? -35.879 18.786 6.961 1.00 37.26 ? 338 LYS B CD 1 ATOM 2426 C CE . LYS B 2 131 ? -36.539 17.467 7.323 1.00 40.82 ? 338 LYS B CE 1 ATOM 2427 N NZ . LYS B 2 131 ? -37.333 17.615 8.581 1.00 43.45 ? 338 LYS B NZ 1 ATOM 2428 N N . ALA B 2 132 ? -32.994 16.471 4.155 1.00 39.19 ? 339 ALA B N 1 ATOM 2429 C CA . ALA B 2 132 ? -32.639 15.066 4.343 1.00 37.60 ? 339 ALA B CA 1 ATOM 2430 C C . ALA B 2 132 ? -33.875 14.286 4.786 1.00 32.45 ? 339 ALA B C 1 ATOM 2431 O O . ALA B 2 132 ? -34.602 14.723 5.672 1.00 35.81 ? 339 ALA B O 1 ATOM 2432 C CB . ALA B 2 132 ? -31.521 14.924 5.363 1.00 35.73 ? 339 ALA B CB 1 ATOM 2433 N N . LYS B 2 133 ? -34.132 13.154 4.135 1.00 39.46 ? 340 LYS B N 1 ATOM 2434 C CA . LYS B 2 133 ? -35.289 12.332 4.483 1.00 43.92 ? 340 LYS B CA 1 ATOM 2435 C C . LYS B 2 133 ? -34.979 11.429 5.674 1.00 43.62 ? 340 LYS B C 1 ATOM 2436 O O . LYS B 2 133 ? -33.844 10.980 5.846 1.00 40.84 ? 340 LYS B O 1 ATOM 2437 C CB . LYS B 2 133 ? -35.767 11.524 3.272 1.00 43.08 ? 340 LYS B CB 1 ATOM 2438 C CG . LYS B 2 133 ? -36.575 12.351 2.282 1.00 38.00 ? 340 LYS B CG 1 ATOM 2439 C CD . LYS B 2 133 ? -36.659 11.684 0.920 1.00 44.17 ? 340 LYS B CD 1 ATOM 2440 C CE . LYS B 2 133 ? -37.167 12.662 -0.128 1.00 40.56 ? 340 LYS B CE 1 ATOM 2441 N N . GLY B 2 134 ? -35.989 11.180 6.502 1.00 38.17 ? 341 GLY B N 1 ATOM 2442 C CA . GLY B 2 134 ? -35.831 10.312 7.661 1.00 33.14 ? 341 GLY B CA 1 ATOM 2443 C C . GLY B 2 134 ? -36.362 10.991 8.903 1.00 35.14 ? 341 GLY B C 1 ATOM 2444 O O . GLY B 2 134 ? -36.372 12.220 8.992 1.00 32.10 ? 341 GLY B O 1 ATOM 2445 N N . GLN B 2 135 ? -36.828 10.197 9.860 1.00 32.13 ? 342 GLN B N 1 ATOM 2446 C CA . GLN B 2 135 ? -37.425 10.763 11.052 1.00 36.14 ? 342 GLN B CA 1 ATOM 2447 C C . GLN B 2 135 ? -36.456 11.712 11.752 1.00 34.96 ? 342 GLN B C 1 ATOM 2448 O O . GLN B 2 135 ? -35.317 11.347 12.019 1.00 42.84 ? 342 GLN B O 1 ATOM 2449 C CB . GLN B 2 135 ? -37.872 9.667 12.007 1.00 38.83 ? 342 GLN B CB 1 ATOM 2450 C CG . GLN B 2 135 ? -38.671 10.203 13.176 1.00 41.78 ? 342 GLN B CG 1 ATOM 2451 C CD . GLN B 2 135 ? -39.132 9.115 14.112 1.00 46.45 ? 342 GLN B CD 1 ATOM 2452 O OE1 . GLN B 2 135 ? -39.023 7.926 13.807 1.00 48.81 ? 342 GLN B OE1 1 ATOM 2453 N NE2 . GLN B 2 135 ? -39.655 9.516 15.265 1.00 50.06 ? 342 GLN B NE2 1 ATOM 2454 N N . PRO B 2 136 ? -36.903 12.943 12.032 1.00 40.12 ? 343 PRO B N 1 ATOM 2455 C CA . PRO B 2 136 ? -36.100 13.826 12.868 1.00 42.90 ? 343 PRO B CA 1 ATOM 2456 C C . PRO B 2 136 ? -35.859 13.198 14.239 1.00 39.49 ? 343 PRO B C 1 ATOM 2457 O O . PRO B 2 136 ? -36.688 12.417 14.697 1.00 40.19 ? 343 PRO B O 1 ATOM 2458 C CB . PRO B 2 136 ? -36.981 15.072 13.004 1.00 37.24 ? 343 PRO B CB 1 ATOM 2459 C CG . PRO B 2 136 ? -37.836 15.059 11.787 1.00 38.35 ? 343 PRO B CG 1 ATOM 2460 C CD . PRO B 2 136 ? -38.112 13.613 11.518 1.00 38.28 ? 343 PRO B CD 1 ATOM 2461 N N . ARG B 2 137 ? -34.733 13.528 14.873 1.00 41.07 ? 344 ARG B N 1 ATOM 2462 C CA . ARG B 2 137 ? -34.426 13.052 16.230 1.00 35.25 ? 344 ARG B CA 1 ATOM 2463 C C . ARG B 2 137 ? -33.824 14.162 17.084 1.00 38.99 ? 344 ARG B C 1 ATOM 2464 O O . ARG B 2 137 ? -32.957 14.911 16.627 1.00 45.95 ? 344 ARG B O 1 ATOM 2465 C CB . ARG B 2 137 ? -33.469 11.858 16.188 1.00 35.29 ? 344 ARG B CB 1 ATOM 2466 C CG . ARG B 2 137 ? -34.099 10.548 15.735 1.00 43.67 ? 344 ARG B CG 1 ATOM 2467 C CD . ARG B 2 137 ? -33.109 9.389 15.797 1.00 47.51 ? 344 ARG B CD 1 ATOM 2468 N NE . ARG B 2 137 ? -32.459 9.282 17.108 1.00 43.81 ? 344 ARG B NE 1 ATOM 2469 C CZ . ARG B 2 137 ? -31.510 8.402 17.406 1.00 43.25 ? 344 ARG B CZ 1 ATOM 2470 N NH1 . ARG B 2 137 ? -31.093 7.538 16.487 1.00 33.46 ? 344 ARG B NH1 1 ATOM 2471 N NH2 . ARG B 2 137 ? -30.980 8.383 18.625 1.00 42.35 ? 344 ARG B NH2 1 ATOM 2472 N N . GLU B 2 138 ? -34.283 14.246 18.327 1.00 41.15 ? 345 GLU B N 1 ATOM 2473 C CA . GLU B 2 138 ? -33.896 15.303 19.254 1.00 43.31 ? 345 GLU B CA 1 ATOM 2474 C C . GLU B 2 138 ? -32.413 15.253 19.648 1.00 48.53 ? 345 GLU B C 1 ATOM 2475 O O . GLU B 2 138 ? -31.929 14.221 20.118 1.00 47.08 ? 345 GLU B O 1 ATOM 2476 C CB . GLU B 2 138 ? -34.766 15.229 20.511 1.00 48.17 ? 345 GLU B CB 1 ATOM 2477 C CG . GLU B 2 138 ? -34.471 16.310 21.540 1.00 51.94 ? 345 GLU B CG 1 ATOM 2478 C CD . GLU B 2 138 ? -35.397 16.262 22.740 1.00 62.64 ? 345 GLU B CD 1 ATOM 2479 O OE1 . GLU B 2 138 ? -36.337 15.437 22.755 1.00 68.68 ? 345 GLU B OE1 1 ATOM 2480 O OE2 . GLU B 2 138 ? -35.179 17.059 23.676 1.00 65.09 ? 345 GLU B OE2 1 ATOM 2481 N N . PRO B 2 139 ? -31.687 16.372 19.455 1.00 48.52 ? 346 PRO B N 1 ATOM 2482 C CA . PRO B 2 139 ? -30.328 16.472 19.996 1.00 44.98 ? 346 PRO B CA 1 ATOM 2483 C C . PRO B 2 139 ? -30.272 16.389 21.530 1.00 47.66 ? 346 PRO B C 1 ATOM 2484 O O . PRO B 2 139 ? -31.074 17.023 22.222 1.00 41.68 ? 346 PRO B O 1 ATOM 2485 C CB . PRO B 2 139 ? -29.844 17.849 19.513 1.00 47.38 ? 346 PRO B CB 1 ATOM 2486 C CG . PRO B 2 139 ? -31.055 18.562 19.015 1.00 45.10 ? 346 PRO B CG 1 ATOM 2487 C CD . PRO B 2 139 ? -32.016 17.505 18.570 1.00 44.21 ? 346 PRO B CD 1 ATOM 2488 N N . GLN B 2 140 ? -29.343 15.581 22.039 1.00 41.90 ? 347 GLN B N 1 ATOM 2489 C CA . GLN B 2 140 ? -29.011 15.571 23.464 1.00 42.99 ? 347 GLN B CA 1 ATOM 2490 C C . GLN B 2 140 ? -27.835 16.521 23.628 1.00 37.13 ? 347 GLN B C 1 ATOM 2491 O O . GLN B 2 140 ? -26.871 16.440 22.872 1.00 35.24 ? 347 GLN B O 1 ATOM 2492 C CB . GLN B 2 140 ? -28.616 14.163 23.911 1.00 45.00 ? 347 GLN B CB 1 ATOM 2493 C CG . GLN B 2 140 ? -29.555 13.059 23.440 1.00 38.30 ? 347 GLN B CG 1 ATOM 2494 C CD . GLN B 2 140 ? -28.869 11.705 23.368 1.00 44.61 ? 347 GLN B CD 1 ATOM 2495 O OE1 . GLN B 2 140 ? -28.824 11.075 22.312 1.00 49.90 ? 347 GLN B OE1 1 ATOM 2496 N NE2 . GLN B 2 140 ? -28.321 11.256 24.486 1.00 33.90 ? 347 GLN B NE2 1 ATOM 2497 N N . VAL B 2 141 ? -27.907 17.427 24.598 1.00 40.17 ? 348 VAL B N 1 ATOM 2498 C CA . VAL B 2 141 ? -26.874 18.456 24.742 1.00 37.36 ? 348 VAL B CA 1 ATOM 2499 C C . VAL B 2 141 ? -26.150 18.363 26.093 1.00 43.60 ? 348 VAL B C 1 ATOM 2500 O O . VAL B 2 141 ? -26.700 18.723 27.142 1.00 40.07 ? 348 VAL B O 1 ATOM 2501 C CB . VAL B 2 141 ? -27.434 19.884 24.499 1.00 37.76 ? 348 VAL B CB 1 ATOM 2502 C CG1 . VAL B 2 141 ? -26.302 20.897 24.413 1.00 33.76 ? 348 VAL B CG1 1 ATOM 2503 C CG2 . VAL B 2 141 ? -28.250 19.939 23.221 1.00 40.43 ? 348 VAL B CG2 1 ATOM 2504 N N . TYR B 2 142 ? -24.904 17.891 26.046 1.00 41.12 ? 349 TYR B N 1 ATOM 2505 C CA . TYR B 2 142 ? -24.125 17.633 27.249 1.00 38.92 ? 349 TYR B CA 1 ATOM 2506 C C . TYR B 2 142 ? -22.911 18.545 27.309 1.00 42.23 ? 349 TYR B C 1 ATOM 2507 O O . TYR B 2 142 ? -22.038 18.499 26.437 1.00 47.77 ? 349 TYR B O 1 ATOM 2508 C CB . TYR B 2 142 ? -23.670 16.172 27.293 1.00 33.62 ? 349 TYR B CB 1 ATOM 2509 C CG . TYR B 2 142 ? -24.769 15.163 27.115 1.00 33.99 ? 349 TYR B CG 1 ATOM 2510 C CD1 . TYR B 2 142 ? -25.864 15.136 27.973 1.00 35.82 ? 349 TYR B CD1 1 ATOM 2511 C CD2 . TYR B 2 142 ? -24.709 14.217 26.096 1.00 34.91 ? 349 TYR B CD2 1 ATOM 2512 C CE1 . TYR B 2 142 ? -26.877 14.204 27.812 1.00 27.90 ? 349 TYR B CE1 1 ATOM 2513 C CE2 . TYR B 2 142 ? -25.715 13.277 25.929 1.00 31.71 ? 349 TYR B CE2 1 ATOM 2514 C CZ . TYR B 2 142 ? -26.796 13.278 26.783 1.00 30.64 ? 349 TYR B CZ 1 ATOM 2515 O OH . TYR B 2 142 ? -27.800 12.343 26.628 1.00 26.88 ? 349 TYR B OH 1 ATOM 2516 N N . THR B 2 143 ? -22.868 19.381 28.336 1.00 41.34 ? 350 THR B N 1 ATOM 2517 C CA . THR B 2 143 ? -21.714 20.226 28.569 1.00 46.66 ? 350 THR B CA 1 ATOM 2518 C C . THR B 2 143 ? -20.721 19.442 29.409 1.00 44.47 ? 350 THR B C 1 ATOM 2519 O O . THR B 2 143 ? -21.096 18.822 30.410 1.00 51.58 ? 350 THR B O 1 ATOM 2520 C CB . THR B 2 143 ? -22.089 21.551 29.267 1.00 44.02 ? 350 THR B CB 1 ATOM 2521 O OG1 . THR B 2 143 ? -22.932 21.283 30.392 1.00 43.92 ? 350 THR B OG1 1 ATOM 2522 C CG2 . THR B 2 143 ? -22.825 22.467 28.308 1.00 46.76 ? 350 THR B CG2 1 ATOM 2523 N N . LEU B 2 144 ? -19.464 19.454 28.978 1.00 43.00 ? 351 LEU B N 1 ATOM 2524 C CA . LEU B 2 144 ? -18.390 18.740 29.668 1.00 47.58 ? 351 LEU B CA 1 ATOM 2525 C C . LEU B 2 144 ? -17.312 19.728 30.098 1.00 47.12 ? 351 LEU B C 1 ATOM 2526 O O . LEU B 2 144 ? -16.721 20.403 29.249 1.00 45.84 ? 351 LEU B O 1 ATOM 2527 C CB . LEU B 2 144 ? -17.774 17.650 28.778 1.00 38.23 ? 351 LEU B CB 1 ATOM 2528 C CG . LEU B 2 144 ? -18.675 16.751 27.921 1.00 36.22 ? 351 LEU B CG 1 ATOM 2529 C CD1 . LEU B 2 144 ? -17.816 15.913 26.989 1.00 38.97 ? 351 LEU B CD1 1 ATOM 2530 C CD2 . LEU B 2 144 ? -19.595 15.862 28.747 1.00 30.54 ? 351 LEU B CD2 1 ATOM 2531 N N . PRO B 2 145 ? -17.061 19.811 31.419 1.00 45.09 ? 352 PRO B N 1 ATOM 2532 C CA . PRO B 2 145 ? -16.074 20.722 32.018 1.00 55.59 ? 352 PRO B CA 1 ATOM 2533 C C . PRO B 2 145 ? -14.628 20.365 31.612 1.00 58.49 ? 352 PRO B C 1 ATOM 2534 O O . PRO B 2 145 ? -14.403 19.284 31.058 1.00 56.95 ? 352 PRO B O 1 ATOM 2535 C CB . PRO B 2 145 ? -16.296 20.537 33.529 1.00 43.46 ? 352 PRO B CB 1 ATOM 2536 C CG . PRO B 2 145 ? -16.885 19.179 33.668 1.00 42.08 ? 352 PRO B CG 1 ATOM 2537 C CD . PRO B 2 145 ? -17.700 18.943 32.430 1.00 46.18 ? 352 PRO B CD 1 ATOM 2538 N N . PRO B 2 146 ? -13.655 21.268 31.866 1.00 63.60 ? 353 PRO B N 1 ATOM 2539 C CA . PRO B 2 146 ? -12.294 20.965 31.420 1.00 63.65 ? 353 PRO B CA 1 ATOM 2540 C C . PRO B 2 146 ? -11.601 19.958 32.330 1.00 59.36 ? 353 PRO B C 1 ATOM 2541 O O . PRO B 2 146 ? -11.840 19.946 33.543 1.00 53.02 ? 353 PRO B O 1 ATOM 2542 C CB . PRO B 2 146 ? -11.576 22.325 31.480 1.00 67.05 ? 353 PRO B CB 1 ATOM 2543 C CG . PRO B 2 146 ? -12.578 23.316 31.980 1.00 67.52 ? 353 PRO B CG 1 ATOM 2544 C CD . PRO B 2 146 ? -13.711 22.549 32.588 1.00 64.67 ? 353 PRO B CD 1 ATOM 2545 N N . SER B 2 147 ? -10.759 19.121 31.726 1.00 56.81 ? 354 SER B N 1 ATOM 2546 C CA . SER B 2 147 ? -9.979 18.103 32.434 1.00 71.29 ? 354 SER B CA 1 ATOM 2547 C C . SER B 2 147 ? -9.046 18.712 33.497 1.00 74.48 ? 354 SER B C 1 ATOM 2548 O O . SER B 2 147 ? -8.562 19.842 33.344 1.00 64.81 ? 354 SER B O 1 ATOM 2549 C CB . SER B 2 147 ? -9.170 17.280 31.418 1.00 66.53 ? 354 SER B CB 1 ATOM 2550 O OG . SER B 2 147 ? -8.602 16.116 31.993 1.00 64.66 ? 354 SER B OG 1 ATOM 2551 N N . ARG B 2 148 ? -8.806 17.957 34.570 1.00 73.76 ? 355 ARG B N 1 ATOM 2552 C CA . ARG B 2 148 ? -7.855 18.356 35.613 1.00 79.98 ? 355 ARG B CA 1 ATOM 2553 C C . ARG B 2 148 ? -6.451 18.601 35.047 1.00 79.47 ? 355 ARG B C 1 ATOM 2554 O O . ARG B 2 148 ? -5.703 19.417 35.587 1.00 81.00 ? 355 ARG B O 1 ATOM 2555 C CB . ARG B 2 148 ? -7.804 17.310 36.731 1.00 78.94 ? 355 ARG B CB 1 ATOM 2556 N N . GLU B 2 149 ? -6.116 17.901 33.958 1.00 88.65 ? 356 GLU B N 1 ATOM 2557 C CA . GLU B 2 149 ? -4.830 18.056 33.257 1.00 84.63 ? 356 GLU B CA 1 ATOM 2558 C C . GLU B 2 149 ? -4.701 19.411 32.559 1.00 83.51 ? 356 GLU B C 1 ATOM 2559 O O . GLU B 2 149 ? -3.619 20.005 32.553 1.00 80.38 ? 356 GLU B O 1 ATOM 2560 C CB . GLU B 2 149 ? -4.625 16.946 32.219 1.00 76.15 ? 356 GLU B CB 1 ATOM 2561 C CG . GLU B 2 149 ? -4.548 15.527 32.762 1.00 84.07 ? 356 GLU B CG 1 ATOM 2562 C CD . GLU B 2 149 ? -4.663 14.480 31.662 1.00 93.60 ? 356 GLU B CD 1 ATOM 2563 O OE1 . GLU B 2 149 ? -3.862 14.518 30.703 1.00 96.97 ? 356 GLU B OE1 1 ATOM 2564 O OE2 . GLU B 2 149 ? -5.559 13.613 31.753 1.00 97.38 ? 356 GLU B OE2 1 ATOM 2565 N N . GLU B 2 150 ? -5.800 19.886 31.969 1.00 82.01 ? 357 GLU B N 1 ATOM 2566 C CA . GLU B 2 150 ? -5.812 21.151 31.219 1.00 90.63 ? 357 GLU B CA 1 ATOM 2567 C C . GLU B 2 150 ? -5.855 22.384 32.131 1.00 87.42 ? 357 GLU B C 1 ATOM 2568 O O . GLU B 2 150 ? -5.644 23.512 31.676 1.00 95.56 ? 357 GLU B O 1 ATOM 2569 C CB . GLU B 2 150 ? -6.975 21.181 30.212 1.00 88.97 ? 357 GLU B CB 1 ATOM 2570 C CG . GLU B 2 150 ? -6.844 22.255 29.132 1.00 77.88 ? 357 GLU B CG 1 ATOM 2571 C CD . GLU B 2 150 ? -7.937 22.195 28.078 1.00 72.90 ? 357 GLU B CD 1 ATOM 2572 O OE1 . GLU B 2 150 ? -9.077 21.795 28.405 1.00 67.05 ? 357 GLU B OE1 1 ATOM 2573 O OE2 . GLU B 2 150 ? -7.654 22.559 26.915 1.00 64.11 ? 357 GLU B OE2 1 ATOM 2574 N N . MET B 2 151 ? -6.119 22.159 33.416 1.00 87.77 ? 358 MET B N 1 ATOM 2575 C CA . MET B 2 151 ? -6.182 23.236 34.402 1.00 92.39 ? 358 MET B CA 1 ATOM 2576 C C . MET B 2 151 ? -4.821 23.898 34.644 1.00 91.51 ? 358 MET B C 1 ATOM 2577 O O . MET B 2 151 ? -4.753 25.031 35.126 1.00 96.37 ? 358 MET B O 1 ATOM 2578 C CB . MET B 2 151 ? -6.793 22.728 35.714 1.00 91.78 ? 358 MET B CB 1 ATOM 2579 C CG . MET B 2 151 ? -8.260 22.331 35.597 1.00 85.79 ? 358 MET B CG 1 ATOM 2580 S SD . MET B 2 151 ? -9.354 23.694 35.133 1.00 86.37 ? 358 MET B SD 1 ATOM 2581 C CE . MET B 2 151 ? -9.815 24.331 36.744 1.00 72.59 ? 358 MET B CE 1 ATOM 2582 N N . THR B 2 152 ? -3.748 23.192 34.290 1.00 94.36 ? 359 THR B N 1 ATOM 2583 C CA . THR B 2 152 ? -2.390 23.731 34.366 1.00 88.18 ? 359 THR B CA 1 ATOM 2584 C C . THR B 2 152 ? -1.947 24.336 33.024 1.00 86.89 ? 359 THR B C 1 ATOM 2585 O O . THR B 2 152 ? -0.810 24.138 32.584 1.00 88.84 ? 359 THR B O 1 ATOM 2586 C CB . THR B 2 152 ? -1.386 22.654 34.829 1.00 75.31 ? 359 THR B CB 1 ATOM 2587 N N . LYS B 2 153 ? -2.858 25.070 32.381 1.00 88.27 ? 360 LYS B N 1 ATOM 2588 C CA . LYS B 2 153 ? -2.585 25.767 31.116 1.00 86.12 ? 360 LYS B CA 1 ATOM 2589 C C . LYS B 2 153 ? -3.193 27.173 31.131 1.00 84.47 ? 360 LYS B C 1 ATOM 2590 O O . LYS B 2 153 ? -4.077 27.465 31.941 1.00 90.13 ? 360 LYS B O 1 ATOM 2591 C CB . LYS B 2 153 ? -3.116 24.966 29.912 1.00 77.08 ? 360 LYS B CB 1 ATOM 2592 C CG . LYS B 2 153 ? -2.369 23.673 29.595 1.00 76.30 ? 360 LYS B CG 1 ATOM 2593 C CD . LYS B 2 153 ? -1.036 23.921 28.902 1.00 67.53 ? 360 LYS B CD 1 ATOM 2594 N N . ASN B 2 154 ? -2.714 28.035 30.233 1.00 89.84 ? 361 ASN B N 1 ATOM 2595 C CA . ASN B 2 154 ? -3.178 29.426 30.138 1.00 93.07 ? 361 ASN B CA 1 ATOM 2596 C C . ASN B 2 154 ? -4.636 29.579 29.692 1.00 105.12 ? 361 ASN B C 1 ATOM 2597 O O . ASN B 2 154 ? -5.338 30.480 30.156 1.00 113.23 ? 361 ASN B O 1 ATOM 2598 C CB . ASN B 2 154 ? -2.263 30.236 29.213 1.00 80.88 ? 361 ASN B CB 1 ATOM 2599 N N . GLN B 2 155 ? -5.079 28.703 28.789 1.00 112.16 ? 362 GLN B N 1 ATOM 2600 C CA . GLN B 2 155 ? -6.451 28.732 28.271 1.00 102.45 ? 362 GLN B CA 1 ATOM 2601 C C . GLN B 2 155 ? -7.101 27.343 28.288 1.00 106.03 ? 362 GLN B C 1 ATOM 2602 O O . GLN B 2 155 ? -6.539 26.375 27.765 1.00 114.95 ? 362 GLN B O 1 ATOM 2603 C CB . GLN B 2 155 ? -6.485 29.330 26.861 1.00 85.63 ? 362 GLN B CB 1 ATOM 2604 C CG . GLN B 2 155 ? -6.320 30.845 26.806 1.00 78.17 ? 362 GLN B CG 1 ATOM 2605 C CD . GLN B 2 155 ? -6.114 31.368 25.392 1.00 82.27 ? 362 GLN B CD 1 ATOM 2606 O OE1 . GLN B 2 155 ? -6.646 30.818 24.426 1.00 79.53 ? 362 GLN B OE1 1 ATOM 2607 N NE2 . GLN B 2 155 ? -5.337 32.439 25.265 1.00 83.58 ? 362 GLN B NE2 1 ATOM 2608 N N . VAL B 2 156 ? -8.286 27.261 28.892 1.00 99.97 ? 363 VAL B N 1 ATOM 2609 C CA . VAL B 2 156 ? -9.003 25.990 29.073 1.00 88.35 ? 363 VAL B CA 1 ATOM 2610 C C . VAL B 2 156 ? -10.088 25.767 28.016 1.00 80.05 ? 363 VAL B C 1 ATOM 2611 O O . VAL B 2 156 ? -10.667 26.728 27.504 1.00 70.40 ? 363 VAL B O 1 ATOM 2612 C CB . VAL B 2 156 ? -9.621 25.875 30.488 1.00 73.28 ? 363 VAL B CB 1 ATOM 2613 C CG1 . VAL B 2 156 ? -8.558 25.481 31.502 1.00 71.49 ? 363 VAL B CG1 1 ATOM 2614 C CG2 . VAL B 2 156 ? -10.311 27.172 30.896 1.00 66.94 ? 363 VAL B CG2 1 ATOM 2615 N N . SER B 2 157 ? -10.349 24.497 27.698 1.00 76.46 ? 364 SER B N 1 ATOM 2616 C CA . SER B 2 157 ? -11.367 24.119 26.711 1.00 71.44 ? 364 SER B CA 1 ATOM 2617 C C . SER B 2 157 ? -12.688 23.731 27.375 1.00 66.98 ? 364 SER B C 1 ATOM 2618 O O . SER B 2 157 ? -12.749 22.786 28.175 1.00 58.25 ? 364 SER B O 1 ATOM 2619 C CB . SER B 2 157 ? -10.872 22.981 25.806 1.00 72.37 ? 364 SER B CB 1 ATOM 2620 O OG . SER B 2 157 ? -9.941 23.444 24.841 1.00 83.49 ? 364 SER B OG 1 ATOM 2621 N N . LEU B 2 158 ? -13.738 24.480 27.045 1.00 59.26 ? 365 LEU B N 1 ATOM 2622 C CA . LEU B 2 158 ? -15.087 24.161 27.495 1.00 52.79 ? 365 LEU B CA 1 ATOM 2623 C C . LEU B 2 158 ? -15.804 23.399 26.399 1.00 45.18 ? 365 LEU B C 1 ATOM 2624 O O . LEU B 2 158 ? -15.877 23.850 25.244 1.00 47.40 ? 365 LEU B O 1 ATOM 2625 C CB . LEU B 2 158 ? -15.867 25.420 27.875 1.00 58.52 ? 365 LEU B CB 1 ATOM 2626 C CG . LEU B 2 158 ? -15.484 26.145 29.164 1.00 54.44 ? 365 LEU B CG 1 ATOM 2627 C CD1 . LEU B 2 158 ? -16.494 27.246 29.439 1.00 56.32 ? 365 LEU B CD1 1 ATOM 2628 C CD2 . LEU B 2 158 ? -15.404 25.183 30.341 1.00 60.52 ? 365 LEU B CD2 1 ATOM 2629 N N . VAL B 2 159 ? -16.316 22.228 26.764 1.00 40.48 ? 366 VAL B N 1 ATOM 2630 C CA . VAL B 2 159 ? -16.837 21.291 25.780 1.00 40.59 ? 366 VAL B CA 1 ATOM 2631 C C . VAL B 2 159 ? -18.344 21.107 25.911 1.00 42.05 ? 366 VAL B C 1 ATOM 2632 O O . VAL B 2 159 ? -18.897 20.995 27.012 1.00 39.41 ? 366 VAL B O 1 ATOM 2633 C CB . VAL B 2 159 ? -16.103 19.931 25.833 1.00 38.31 ? 366 VAL B CB 1 ATOM 2634 C CG1 . VAL B 2 159 ? -16.469 19.077 24.631 1.00 37.45 ? 366 VAL B CG1 1 ATOM 2635 C CG2 . VAL B 2 159 ? -14.596 20.139 25.870 1.00 40.75 ? 366 VAL B CG2 1 ATOM 2636 N N . CYS B 2 160 ? -18.992 21.097 24.757 1.00 39.25 ? 367 CYS B N 1 ATOM 2637 C CA . CYS B 2 160 ? -20.406 20.832 24.643 1.00 38.92 ? 367 CYS B CA 1 ATOM 2638 C C . CYS B 2 160 ? -20.529 19.787 23.550 1.00 36.56 ? 367 CYS B C 1 ATOM 2639 O O . CYS B 2 160 ? -20.227 20.064 22.380 1.00 32.74 ? 367 CYS B O 1 ATOM 2640 C CB . CYS B 2 160 ? -21.137 22.121 24.250 1.00 44.59 ? 367 CYS B CB 1 ATOM 2641 S SG . CYS B 2 160 ? -22.927 22.018 24.022 1.00 54.95 ? 367 CYS B SG 1 ATOM 2642 N N . LEU B 2 161 ? -20.925 18.580 23.951 1.00 33.48 ? 368 LEU B N 1 ATOM 2643 C CA . LEU B 2 161 ? -21.200 17.478 23.032 1.00 34.57 ? 368 LEU B CA 1 ATOM 2644 C C . LEU B 2 161 ? -22.671 17.439 22.640 1.00 32.23 ? 368 LEU B C 1 ATOM 2645 O O . LEU B 2 161 ? -23.551 17.422 23.491 1.00 33.92 ? 368 LEU B O 1 ATOM 2646 C CB . LEU B 2 161 ? -20.793 16.143 23.671 1.00 33.74 ? 368 LEU B CB 1 ATOM 2647 C CG . LEU B 2 161 ? -21.370 14.801 23.205 1.00 33.37 ? 368 LEU B CG 1 ATOM 2648 C CD1 . LEU B 2 161 ? -20.998 14.456 21.766 1.00 26.37 ? 368 LEU B CD1 1 ATOM 2649 C CD2 . LEU B 2 161 ? -20.895 13.711 24.151 1.00 27.56 ? 368 LEU B CD2 1 ATOM 2650 N N . VAL B 2 162 ? -22.926 17.410 21.338 1.00 34.76 ? 369 VAL B N 1 ATOM 2651 C CA . VAL B 2 162 ? -24.278 17.351 20.828 1.00 29.68 ? 369 VAL B CA 1 ATOM 2652 C C . VAL B 2 162 ? -24.399 16.064 20.040 1.00 33.09 ? 369 VAL B C 1 ATOM 2653 O O . VAL B 2 162 ? -23.703 15.878 19.052 1.00 35.55 ? 369 VAL B O 1 ATOM 2654 C CB . VAL B 2 162 ? -24.628 18.565 19.932 1.00 30.20 ? 369 VAL B CB 1 ATOM 2655 C CG1 . VAL B 2 162 ? -26.123 18.582 19.636 1.00 30.29 ? 369 VAL B CG1 1 ATOM 2656 C CG2 . VAL B 2 162 ? -24.220 19.883 20.584 1.00 31.62 ? 369 VAL B CG2 1 ATOM 2657 N N . LYS B 2 163 ? -25.282 15.171 20.479 1.00 35.69 ? 370 LYS B N 1 ATOM 2658 C CA . LYS B 2 163 ? -25.358 13.841 19.876 1.00 35.12 ? 370 LYS B CA 1 ATOM 2659 C C . LYS B 2 163 ? -26.780 13.329 19.613 1.00 34.90 ? 370 LYS B C 1 ATOM 2660 O O . LYS B 2 163 ? -27.759 13.867 20.129 1.00 33.93 ? 370 LYS B O 1 ATOM 2661 C CB . LYS B 2 163 ? -24.548 12.844 20.706 1.00 31.91 ? 370 LYS B CB 1 ATOM 2662 C CG . LYS B 2 163 ? -25.097 12.538 22.089 1.00 31.49 ? 370 LYS B CG 1 ATOM 2663 C CD . LYS B 2 163 ? -24.502 11.212 22.553 1.00 35.68 ? 370 LYS B CD 1 ATOM 2664 C CE . LYS B 2 163 ? -25.584 10.243 22.987 1.00 32.01 ? 370 LYS B CE 1 ATOM 2665 N NZ . LYS B 2 163 ? -25.229 8.832 22.693 1.00 42.81 ? 370 LYS B NZ 1 ATOM 2666 N N . GLY B 2 164 ? -26.884 12.301 18.779 1.00 37.89 ? 371 GLY B N 1 ATOM 2667 C CA . GLY B 2 164 ? -28.177 11.677 18.489 1.00 37.56 ? 371 GLY B CA 1 ATOM 2668 C C . GLY B 2 164 ? -29.194 12.504 17.706 1.00 38.42 ? 371 GLY B C 1 ATOM 2669 O O . GLY B 2 164 ? -30.392 12.217 17.747 1.00 40.78 ? 371 GLY B O 1 ATOM 2670 N N . PHE B 2 165 ? -28.738 13.523 16.983 1.00 33.82 ? 372 PHE B N 1 ATOM 2671 C CA . PHE B 2 165 ? -29.665 14.332 16.197 1.00 36.06 ? 372 PHE B CA 1 ATOM 2672 C C . PHE B 2 165 ? -29.784 13.852 14.760 1.00 31.32 ? 372 PHE B C 1 ATOM 2673 O O . PHE B 2 165 ? -28.856 13.255 14.217 1.00 31.59 ? 372 PHE B O 1 ATOM 2674 C CB . PHE B 2 165 ? -29.355 15.844 16.267 1.00 35.35 ? 372 PHE B CB 1 ATOM 2675 C CG . PHE B 2 165 ? -27.954 16.221 15.858 1.00 32.74 ? 372 PHE B CG 1 ATOM 2676 C CD1 . PHE B 2 165 ? -26.921 16.248 16.797 1.00 33.41 ? 372 PHE B CD1 1 ATOM 2677 C CD2 . PHE B 2 165 ? -27.674 16.603 14.551 1.00 28.68 ? 372 PHE B CD2 1 ATOM 2678 C CE1 . PHE B 2 165 ? -25.633 16.620 16.426 1.00 37.26 ? 372 PHE B CE1 1 ATOM 2679 C CE2 . PHE B 2 165 ? -26.389 16.978 14.178 1.00 30.42 ? 372 PHE B CE2 1 ATOM 2680 C CZ . PHE B 2 165 ? -25.365 16.986 15.114 1.00 25.80 ? 372 PHE B CZ 1 ATOM 2681 N N . TYR B 2 166 ? -30.955 14.096 14.178 1.00 35.26 ? 373 TYR B N 1 ATOM 2682 C CA . TYR B 2 166 ? -31.196 13.913 12.746 1.00 36.48 ? 373 TYR B CA 1 ATOM 2683 C C . TYR B 2 166 ? -32.313 14.865 12.299 1.00 40.20 ? 373 TYR B C 1 ATOM 2684 O O . TYR B 2 166 ? -33.300 15.023 13.016 1.00 37.32 ? 373 TYR B O 1 ATOM 2685 C CB . TYR B 2 166 ? -31.580 12.462 12.420 1.00 34.51 ? 373 TYR B CB 1 ATOM 2686 C CG . TYR B 2 166 ? -31.593 12.196 10.934 1.00 35.79 ? 373 TYR B CG 1 ATOM 2687 C CD1 . TYR B 2 166 ? -32.774 12.289 10.194 1.00 35.06 ? 373 TYR B CD1 1 ATOM 2688 C CD2 . TYR B 2 166 ? -30.417 11.874 10.260 1.00 38.81 ? 373 TYR B CD2 1 ATOM 2689 C CE1 . TYR B 2 166 ? -32.777 12.064 8.822 1.00 37.91 ? 373 TYR B CE1 1 ATOM 2690 C CE2 . TYR B 2 166 ? -30.409 11.656 8.889 1.00 38.55 ? 373 TYR B CE2 1 ATOM 2691 C CZ . TYR B 2 166 ? -31.590 11.751 8.175 1.00 36.86 ? 373 TYR B CZ 1 ATOM 2692 O OH . TYR B 2 166 ? -31.573 11.527 6.816 1.00 38.72 ? 373 TYR B OH 1 ATOM 2693 N N . PRO B 2 167 ? -32.168 15.501 11.116 1.00 45.31 ? 374 PRO B N 1 ATOM 2694 C CA . PRO B 2 167 ? -30.987 15.485 10.242 1.00 44.79 ? 374 PRO B CA 1 ATOM 2695 C C . PRO B 2 167 ? -29.784 16.233 10.834 1.00 38.29 ? 374 PRO B C 1 ATOM 2696 O O . PRO B 2 167 ? -29.837 16.698 11.975 1.00 38.65 ? 374 PRO B O 1 ATOM 2697 C CB . PRO B 2 167 ? -31.488 16.141 8.945 1.00 43.85 ? 374 PRO B CB 1 ATOM 2698 C CG . PRO B 2 167 ? -32.733 16.877 9.316 1.00 39.71 ? 374 PRO B CG 1 ATOM 2699 C CD . PRO B 2 167 ? -33.341 16.077 10.431 1.00 46.64 ? 374 PRO B CD 1 ATOM 2700 N N . SER B 2 168 ? -28.706 16.307 10.066 1.00 35.46 ? 375 SER B N 1 ATOM 2701 C CA . SER B 2 168 ? -27.457 16.914 10.506 1.00 38.06 ? 375 SER B CA 1 ATOM 2702 C C . SER B 2 168 ? -27.498 18.441 10.485 1.00 38.91 ? 375 SER B C 1 ATOM 2703 O O . SER B 2 168 ? -26.573 19.097 10.961 1.00 42.03 ? 375 SER B O 1 ATOM 2704 C CB . SER B 2 168 ? -26.338 16.462 9.590 1.00 41.69 ? 375 SER B CB 1 ATOM 2705 O OG . SER B 2 168 ? -26.495 17.076 8.324 1.00 55.20 ? 375 SER B OG 1 ATOM 2706 N N . ASP B 2 169 ? -28.562 18.997 9.915 1.00 45.50 ? 376 ASP B N 1 ATOM 2707 C CA . ASP B 2 169 ? -28.767 20.445 9.866 1.00 46.26 ? 376 ASP B CA 1 ATOM 2708 C C . ASP B 2 169 ? -28.906 21.036 11.272 1.00 41.31 ? 376 ASP B C 1 ATOM 2709 O O . ASP B 2 169 ? -29.901 20.805 11.957 1.00 42.29 ? 376 ASP B O 1 ATOM 2710 C CB . ASP B 2 169 ? -29.991 20.768 9.004 1.00 50.97 ? 376 ASP B CB 1 ATOM 2711 C CG . ASP B 2 169 ? -29.798 20.368 7.545 1.00 66.22 ? 376 ASP B CG 1 ATOM 2712 O OD1 . ASP B 2 169 ? -30.745 19.799 6.951 1.00 71.57 ? 376 ASP B OD1 1 ATOM 2713 O OD2 . ASP B 2 169 ? -28.696 20.616 6.999 1.00 58.56 ? 376 ASP B OD2 1 ATOM 2714 N N . ILE B 2 170 ? -27.895 21.795 11.690 1.00 39.70 ? 377 ILE B N 1 ATOM 2715 C CA . ILE B 2 170 ? -27.799 22.271 13.073 1.00 45.42 ? 377 ILE B CA 1 ATOM 2716 C C . ILE B 2 170 ? -26.935 23.538 13.181 1.00 43.22 ? 377 ILE B C 1 ATOM 2717 O O . ILE B 2 170 ? -26.173 23.862 12.267 1.00 43.91 ? 377 ILE B O 1 ATOM 2718 C CB . ILE B 2 170 ? -27.236 21.160 14.003 1.00 45.29 ? 377 ILE B CB 1 ATOM 2719 C CG1 . ILE B 2 170 ? -27.586 21.424 15.477 1.00 39.12 ? 377 ILE B CG1 1 ATOM 2720 C CG2 . ILE B 2 170 ? -25.732 20.983 13.792 1.00 38.66 ? 377 ILE B CG2 1 ATOM 2721 C CD1 . ILE B 2 170 ? -27.296 20.249 16.392 1.00 45.84 ? 377 ILE B CD1 1 ATOM 2722 N N . ALA B 2 171 ? -27.068 24.242 14.303 1.00 34.05 ? 378 ALA B N 1 ATOM 2723 C CA . ALA B 2 171 ? -26.256 25.406 14.600 1.00 38.49 ? 378 ALA B CA 1 ATOM 2724 C C . ALA B 2 171 ? -25.883 25.387 16.071 1.00 43.34 ? 378 ALA B C 1 ATOM 2725 O O . ALA B 2 171 ? -26.733 25.151 16.931 1.00 39.96 ? 378 ALA B O 1 ATOM 2726 C CB . ALA B 2 171 ? -27.016 26.681 14.268 1.00 44.70 ? 378 ALA B CB 1 ATOM 2727 N N . VAL B 2 172 ? -24.609 25.633 16.356 1.00 46.89 ? 379 VAL B N 1 ATOM 2728 C CA . VAL B 2 172 ? -24.134 25.704 17.734 1.00 46.59 ? 379 VAL B CA 1 ATOM 2729 C C . VAL B 2 172 ? -23.404 27.025 17.984 1.00 43.87 ? 379 VAL B C 1 ATOM 2730 O O . VAL B 2 172 ? -22.534 27.427 17.206 1.00 47.28 ? 379 VAL B O 1 ATOM 2731 C CB . VAL B 2 172 ? -23.212 24.508 18.106 1.00 44.28 ? 379 VAL B CB 1 ATOM 2732 C CG1 . VAL B 2 172 ? -22.830 24.571 19.579 1.00 34.81 ? 379 VAL B CG1 1 ATOM 2733 C CG2 . VAL B 2 172 ? -23.886 23.172 17.797 1.00 38.38 ? 379 VAL B CG2 1 ATOM 2734 N N . GLU B 2 173 ? -23.769 27.687 19.078 1.00 38.68 ? 380 GLU B N 1 ATOM 2735 C CA . GLU B 2 173 ? -23.129 28.921 19.513 1.00 45.51 ? 380 GLU B CA 1 ATOM 2736 C C . GLU B 2 173 ? -22.983 28.895 21.028 1.00 45.58 ? 380 GLU B C 1 ATOM 2737 O O . GLU B 2 173 ? -23.598 28.064 21.703 1.00 37.85 ? 380 GLU B O 1 ATOM 2738 C CB . GLU B 2 173 ? -23.963 30.140 19.100 1.00 52.16 ? 380 GLU B CB 1 ATOM 2739 C CG . GLU B 2 173 ? -23.935 30.453 17.612 1.00 52.87 ? 380 GLU B CG 1 ATOM 2740 C CD . GLU B 2 173 ? -25.202 31.133 17.129 1.00 70.27 ? 380 GLU B CD 1 ATOM 2741 O OE1 . GLU B 2 173 ? -25.793 31.934 17.892 1.00 67.27 ? 380 GLU B OE1 1 ATOM 2742 O OE2 . GLU B 2 173 ? -25.605 30.860 15.977 1.00 79.99 ? 380 GLU B OE2 1 ATOM 2743 N N . TRP B 2 174 ? -22.169 29.813 21.543 1.00 43.73 ? 381 TRP B N 1 ATOM 2744 C CA . TRP B 2 174 ? -21.905 29.944 22.972 1.00 52.17 ? 381 TRP B CA 1 ATOM 2745 C C . TRP B 2 174 ? -22.190 31.352 23.396 1.00 60.62 ? 381 TRP B C 1 ATOM 2746 O O . TRP B 2 174 ? -22.091 32.284 22.586 1.00 61.39 ? 381 TRP B O 1 ATOM 2747 C CB . TRP B 2 174 ? -20.440 29.650 23.280 1.00 51.69 ? 381 TRP B CB 1 ATOM 2748 C CG . TRP B 2 174 ? -19.995 28.215 23.095 1.00 42.47 ? 381 TRP B CG 1 ATOM 2749 C CD1 . TRP B 2 174 ? -19.677 27.568 21.903 1.00 38.47 ? 381 TRP B CD1 1 ATOM 2750 C CD2 . TRP B 2 174 ? -19.767 27.211 24.143 1.00 36.12 ? 381 TRP B CD2 1 ATOM 2751 N NE1 . TRP B 2 174 ? -19.295 26.272 22.135 1.00 37.10 ? 381 TRP B NE1 1 ATOM 2752 C CE2 . TRP B 2 174 ? -19.331 25.991 23.454 1.00 40.30 ? 381 TRP B CE2 1 ATOM 2753 C CE3 . TRP B 2 174 ? -19.893 27.196 25.523 1.00 39.11 ? 381 TRP B CE3 1 ATOM 2754 C CZ2 . TRP B 2 174 ? -19.025 24.828 24.143 1.00 39.58 ? 381 TRP B CZ2 1 ATOM 2755 C CZ3 . TRP B 2 174 ? -19.588 26.014 26.207 1.00 43.34 ? 381 TRP B CZ3 1 ATOM 2756 C CH2 . TRP B 2 174 ? -19.160 24.861 25.532 1.00 38.26 ? 381 TRP B CH2 1 ATOM 2757 N N . GLU B 2 175 ? -22.525 31.519 24.676 1.00 60.96 ? 382 GLU B N 1 ATOM 2758 C CA . GLU B 2 175 ? -22.789 32.837 25.256 1.00 70.64 ? 382 GLU B CA 1 ATOM 2759 C C . GLU B 2 175 ? -22.577 32.879 26.777 1.00 71.66 ? 382 GLU B C 1 ATOM 2760 O O . GLU B 2 175 ? -22.317 31.848 27.404 1.00 67.30 ? 382 GLU B O 1 ATOM 2761 C CB . GLU B 2 175 ? -24.196 33.333 24.880 1.00 83.15 ? 382 GLU B CB 1 ATOM 2762 C CG . GLU B 2 175 ? -25.292 32.280 24.948 1.00 88.33 ? 382 GLU B CG 1 ATOM 2763 C CD . GLU B 2 175 ? -26.606 32.780 24.390 1.00 95.38 ? 382 GLU B CD 1 ATOM 2764 O OE1 . GLU B 2 175 ? -27.277 33.581 25.078 1.00 98.55 ? 382 GLU B OE1 1 ATOM 2765 O OE2 . GLU B 2 175 ? -26.971 32.365 23.268 1.00 98.28 ? 382 GLU B OE2 1 ATOM 2766 N N . SER B 2 176 ? -22.681 34.083 27.346 1.00 71.50 ? 383 SER B N 1 ATOM 2767 C CA . SER B 2 176 ? -22.508 34.325 28.780 1.00 68.67 ? 383 SER B CA 1 ATOM 2768 C C . SER B 2 176 ? -23.070 35.702 29.153 1.00 74.94 ? 383 SER B C 1 ATOM 2769 O O . SER B 2 176 ? -22.670 36.721 28.579 1.00 70.53 ? 383 SER B O 1 ATOM 2770 C CB . SER B 2 176 ? -21.026 34.239 29.163 1.00 67.75 ? 383 SER B CB 1 ATOM 2771 O OG . SER B 2 176 ? -20.864 34.028 30.554 1.00 80.51 ? 383 SER B OG 1 ATOM 2772 N N . ASN B 2 177 ? -23.999 35.717 30.112 1.00 78.18 ? 384 ASN B N 1 ATOM 2773 C CA . ASN B 2 177 ? -24.662 36.945 30.593 1.00 79.05 ? 384 ASN B CA 1 ATOM 2774 C C . ASN B 2 177 ? -25.512 37.665 29.538 1.00 80.71 ? 384 ASN B C 1 ATOM 2775 O O . ASN B 2 177 ? -25.864 38.834 29.706 1.00 90.38 ? 384 ASN B O 1 ATOM 2776 C CB . ASN B 2 177 ? -23.647 37.923 31.209 1.00 77.86 ? 384 ASN B CB 1 ATOM 2777 C CG . ASN B 2 177 ? -22.833 37.300 32.324 1.00 82.57 ? 384 ASN B CG 1 ATOM 2778 O OD1 . ASN B 2 177 ? -23.380 36.743 33.278 1.00 92.10 ? 384 ASN B OD1 1 ATOM 2779 N ND2 . ASN B 2 177 ? -21.514 37.400 32.213 1.00 78.15 ? 384 ASN B ND2 1 ATOM 2780 N N . GLY B 2 178 ? -25.850 36.959 28.462 1.00 81.06 ? 385 GLY B N 1 ATOM 2781 C CA . GLY B 2 178 ? -26.546 37.559 27.327 1.00 67.13 ? 385 GLY B CA 1 ATOM 2782 C C . GLY B 2 178 ? -25.570 37.973 26.243 1.00 75.03 ? 385 GLY B C 1 ATOM 2783 O O . GLY B 2 178 ? -25.959 38.177 25.090 1.00 77.96 ? 385 GLY B O 1 ATOM 2784 N N . GLN B 2 179 ? -24.298 38.091 26.618 1.00 74.62 ? 386 GLN B N 1 ATOM 2785 C CA . GLN B 2 179 ? -23.244 38.489 25.693 1.00 83.84 ? 386 GLN B CA 1 ATOM 2786 C C . GLN B 2 179 ? -22.663 37.271 24.965 1.00 89.11 ? 386 GLN B C 1 ATOM 2787 O O . GLN B 2 179 ? -22.150 36.352 25.610 1.00 86.96 ? 386 GLN B O 1 ATOM 2788 C CB . GLN B 2 179 ? -22.144 39.259 26.433 1.00 79.34 ? 386 GLN B CB 1 ATOM 2789 N N . PRO B 2 180 ? -22.750 37.258 23.618 1.00 89.72 ? 387 PRO B N 1 ATOM 2790 C CA . PRO B 2 180 ? -22.255 36.127 22.823 1.00 84.33 ? 387 PRO B CA 1 ATOM 2791 C C . PRO B 2 180 ? -20.728 36.007 22.789 1.00 86.27 ? 387 PRO B C 1 ATOM 2792 O O . PRO B 2 180 ? -20.046 36.890 22.263 1.00 86.69 ? 387 PRO B O 1 ATOM 2793 C CB . PRO B 2 180 ? -22.806 36.408 21.419 1.00 79.72 ? 387 PRO B CB 1 ATOM 2794 C CG . PRO B 2 180 ? -23.044 37.877 21.385 1.00 83.66 ? 387 PRO B CG 1 ATOM 2795 C CD . PRO B 2 180 ? -23.421 38.272 22.782 1.00 81.02 ? 387 PRO B CD 1 ATOM 2796 N N . GLU B 2 181 ? -20.213 34.916 23.356 1.00 87.72 ? 388 GLU B N 1 ATOM 2797 C CA . GLU B 2 181 ? -18.791 34.573 23.273 1.00 74.01 ? 388 GLU B CA 1 ATOM 2798 C C . GLU B 2 181 ? -18.484 34.119 21.854 1.00 67.38 ? 388 GLU B C 1 ATOM 2799 O O . GLU B 2 181 ? -19.160 33.234 21.327 1.00 66.04 ? 388 GLU B O 1 ATOM 2800 C CB . GLU B 2 181 ? -18.446 33.450 24.253 1.00 70.84 ? 388 GLU B CB 1 ATOM 2801 C CG . GLU B 2 181 ? -18.740 33.752 25.716 1.00 78.82 ? 388 GLU B CG 1 ATOM 2802 C CD . GLU B 2 181 ? -17.598 34.459 26.425 1.00 80.41 ? 388 GLU B CD 1 ATOM 2803 O OE1 . GLU B 2 181 ? -16.544 34.694 25.796 1.00 81.44 ? 388 GLU B OE1 1 ATOM 2804 O OE2 . GLU B 2 181 ? -17.756 34.776 27.623 1.00 84.76 ? 388 GLU B OE2 1 ATOM 2805 N N . ASN B 2 182 ? -17.470 34.725 21.240 1.00 74.00 ? 389 ASN B N 1 ATOM 2806 C CA . ASN B 2 182 ? -17.142 34.451 19.838 1.00 74.26 ? 389 ASN B CA 1 ATOM 2807 C C . ASN B 2 182 ? -16.018 33.429 19.646 1.00 72.72 ? 389 ASN B C 1 ATOM 2808 O O . ASN B 2 182 ? -15.798 32.944 18.531 1.00 74.76 ? 389 ASN B O 1 ATOM 2809 C CB . ASN B 2 182 ? -16.816 35.753 19.096 1.00 64.16 ? 389 ASN B CB 1 ATOM 2810 N N . ASN B 2 183 ? -15.325 33.096 20.733 1.00 71.26 ? 390 ASN B N 1 ATOM 2811 C CA . ASN B 2 183 ? -14.136 32.246 20.662 1.00 71.75 ? 390 ASN B CA 1 ATOM 2812 C C . ASN B 2 183 ? -14.385 30.743 20.845 1.00 69.97 ? 390 ASN B C 1 ATOM 2813 O O . ASN B 2 183 ? -14.154 30.188 21.922 1.00 75.82 ? 390 ASN B O 1 ATOM 2814 C CB . ASN B 2 183 ? -13.065 32.731 21.644 1.00 67.89 ? 390 ASN B CB 1 ATOM 2815 C CG . ASN B 2 183 ? -11.705 32.126 21.362 1.00 59.04 ? 390 ASN B CG 1 ATOM 2816 O OD1 . ASN B 2 183 ? -11.391 31.772 20.222 1.00 54.92 ? 390 ASN B OD1 1 ATOM 2817 N ND2 . ASN B 2 183 ? -10.889 32.004 22.400 1.00 56.51 ? 390 ASN B ND2 1 ATOM 2818 N N . TYR B 2 184 ? -14.834 30.094 19.775 1.00 65.15 ? 391 TYR B N 1 ATOM 2819 C CA . TYR B 2 184 ? -15.048 28.650 19.776 1.00 57.80 ? 391 TYR B CA 1 ATOM 2820 C C . TYR B 2 184 ? -14.894 28.051 18.386 1.00 66.44 ? 391 TYR B C 1 ATOM 2821 O O . TYR B 2 184 ? -14.934 28.761 17.378 1.00 71.96 ? 391 TYR B O 1 ATOM 2822 C CB . TYR B 2 184 ? -16.433 28.297 20.339 1.00 51.64 ? 391 TYR B CB 1 ATOM 2823 C CG . TYR B 2 184 ? -17.576 28.918 19.585 1.00 44.32 ? 391 TYR B CG 1 ATOM 2824 C CD1 . TYR B 2 184 ? -18.011 28.381 18.372 1.00 42.06 ? 391 TYR B CD1 1 ATOM 2825 C CD2 . TYR B 2 184 ? -18.221 30.057 20.075 1.00 41.39 ? 391 TYR B CD2 1 ATOM 2826 C CE1 . TYR B 2 184 ? -19.052 28.960 17.670 1.00 45.02 ? 391 TYR B CE1 1 ATOM 2827 C CE2 . TYR B 2 184 ? -19.273 30.638 19.385 1.00 42.24 ? 391 TYR B CE2 1 ATOM 2828 C CZ . TYR B 2 184 ? -19.680 30.090 18.180 1.00 41.45 ? 391 TYR B CZ 1 ATOM 2829 O OH . TYR B 2 184 ? -20.726 30.655 17.487 1.00 45.75 ? 391 TYR B OH 1 ATOM 2830 N N . LYS B 2 185 ? -14.731 26.734 18.348 1.00 65.76 ? 392 LYS B N 1 ATOM 2831 C CA . LYS B 2 185 ? -14.691 25.991 17.100 1.00 55.39 ? 392 LYS B CA 1 ATOM 2832 C C . LYS B 2 185 ? -15.624 24.784 17.188 1.00 49.14 ? 392 LYS B C 1 ATOM 2833 O O . LYS B 2 185 ? -15.854 24.239 18.277 1.00 43.70 ? 392 LYS B O 1 ATOM 2834 C CB . LYS B 2 185 ? -13.261 25.554 16.799 1.00 60.28 ? 392 LYS B CB 1 ATOM 2835 C CG . LYS B 2 185 ? -12.333 26.678 16.363 1.00 52.84 ? 392 LYS B CG 1 ATOM 2836 C CD . LYS B 2 185 ? -12.336 26.823 14.852 1.00 55.11 ? 392 LYS B CD 1 ATOM 2837 C CE . LYS B 2 185 ? -11.560 28.053 14.412 1.00 56.26 ? 392 LYS B CE 1 ATOM 2838 N NZ . LYS B 2 185 ? -11.731 28.259 12.948 1.00 52.72 ? 392 LYS B NZ 1 ATOM 2839 N N . THR B 2 186 ? -16.157 24.373 16.041 1.00 42.25 ? 393 THR B N 1 ATOM 2840 C CA . THR B 2 186 ? -17.159 23.311 15.986 1.00 38.78 ? 393 THR B CA 1 ATOM 2841 C C . THR B 2 186 ? -16.878 22.319 14.859 1.00 40.24 ? 393 THR B C 1 ATOM 2842 O O . THR B 2 186 ? -16.626 22.707 13.705 1.00 37.92 ? 393 THR B O 1 ATOM 2843 C CB . THR B 2 186 ? -18.586 23.901 15.873 1.00 43.24 ? 393 THR B CB 1 ATOM 2844 O OG1 . THR B 2 186 ? -18.941 24.538 17.111 1.00 39.57 ? 393 THR B OG1 1 ATOM 2845 C CG2 . THR B 2 186 ? -19.622 22.826 15.566 1.00 44.57 ? 393 THR B CG2 1 ATOM 2846 N N . THR B 2 187 ? -16.914 21.034 15.202 1.00 35.98 ? 394 THR B N 1 ATOM 2847 C CA . THR B 2 187 ? -16.651 19.989 14.224 1.00 36.71 ? 394 THR B CA 1 ATOM 2848 C C . THR B 2 187 ? -17.860 19.855 13.304 1.00 35.46 ? 394 THR B C 1 ATOM 2849 O O . THR B 2 187 ? -18.986 20.098 13.731 1.00 29.41 ? 394 THR B O 1 ATOM 2850 C CB . THR B 2 187 ? -16.344 18.627 14.890 1.00 39.24 ? 394 THR B CB 1 ATOM 2851 O OG1 . THR B 2 187 ? -17.511 18.136 15.565 1.00 40.64 ? 394 THR B OG1 1 ATOM 2852 C CG2 . THR B 2 187 ? -15.176 18.747 15.877 1.00 34.86 ? 394 THR B CG2 1 ATOM 2853 N N . PRO B 2 188 ? -17.633 19.488 12.030 1.00 40.76 ? 395 PRO B N 1 ATOM 2854 C CA . PRO B 2 188 ? -18.788 19.146 11.204 1.00 42.49 ? 395 PRO B CA 1 ATOM 2855 C C . PRO B 2 188 ? -19.490 17.904 11.788 1.00 46.63 ? 395 PRO B C 1 ATOM 2856 O O . PRO B 2 188 ? -18.870 17.139 12.535 1.00 49.49 ? 395 PRO B O 1 ATOM 2857 C CB . PRO B 2 188 ? -18.169 18.849 9.829 1.00 41.21 ? 395 PRO B CB 1 ATOM 2858 C CG . PRO B 2 188 ? -16.749 18.506 10.111 1.00 41.80 ? 395 PRO B CG 1 ATOM 2859 C CD . PRO B 2 188 ? -16.360 19.326 11.307 1.00 39.90 ? 395 PRO B CD 1 ATOM 2860 N N . PRO B 2 189 ? -20.783 17.719 11.484 1.00 42.40 ? 396 PRO B N 1 ATOM 2861 C CA . PRO B 2 189 ? -21.472 16.571 12.051 1.00 41.17 ? 396 PRO B CA 1 ATOM 2862 C C . PRO B 2 189 ? -20.861 15.268 11.571 1.00 38.28 ? 396 PRO B C 1 ATOM 2863 O O . PRO B 2 189 ? -20.477 15.158 10.407 1.00 36.75 ? 396 PRO B O 1 ATOM 2864 C CB . PRO B 2 189 ? -22.894 16.713 11.507 1.00 42.05 ? 396 PRO B CB 1 ATOM 2865 C CG . PRO B 2 189 ? -23.045 18.159 11.181 1.00 42.37 ? 396 PRO B CG 1 ATOM 2866 C CD . PRO B 2 189 ? -21.691 18.584 10.711 1.00 43.57 ? 396 PRO B CD 1 ATOM 2867 N N . VAL B 2 190 ? -20.760 14.296 12.470 1.00 32.63 ? 397 VAL B N 1 ATOM 2868 C CA . VAL B 2 190 ? -20.283 12.965 12.108 1.00 31.56 ? 397 VAL B CA 1 ATOM 2869 C C . VAL B 2 190 ? -21.437 11.972 12.205 1.00 32.52 ? 397 VAL B C 1 ATOM 2870 O O . VAL B 2 190 ? -22.160 11.956 13.200 1.00 37.87 ? 397 VAL B O 1 ATOM 2871 C CB . VAL B 2 190 ? -19.125 12.506 13.016 1.00 31.15 ? 397 VAL B CB 1 ATOM 2872 C CG1 . VAL B 2 190 ? -18.618 11.133 12.593 1.00 33.58 ? 397 VAL B CG1 1 ATOM 2873 C CG2 . VAL B 2 190 ? -17.992 13.519 13.000 1.00 27.58 ? 397 VAL B CG2 1 ATOM 2874 N N . LEU B 2 191 ? -21.602 11.159 11.165 1.00 32.44 ? 398 LEU B N 1 ATOM 2875 C CA . LEU B 2 191 ? -22.559 10.059 11.161 1.00 37.66 ? 398 LEU B CA 1 ATOM 2876 C C . LEU B 2 191 ? -22.211 9.033 12.236 1.00 33.52 ? 398 LEU B C 1 ATOM 2877 O O . LEU B 2 191 ? -21.087 8.553 12.305 1.00 38.75 ? 398 LEU B O 1 ATOM 2878 C CB . LEU B 2 191 ? -22.622 9.378 9.779 1.00 33.94 ? 398 LEU B CB 1 ATOM 2879 C CG . LEU B 2 191 ? -23.601 8.194 9.647 1.00 37.45 ? 398 LEU B CG 1 ATOM 2880 C CD1 . LEU B 2 191 ? -25.049 8.610 9.914 1.00 38.00 ? 398 LEU B CD1 1 ATOM 2881 C CD2 . LEU B 2 191 ? -23.492 7.505 8.289 1.00 27.91 ? 398 LEU B CD2 1 ATOM 2882 N N . ASP B 2 192 ? -23.186 8.705 13.070 1.00 33.90 ? 399 ASP B N 1 ATOM 2883 C CA . ASP B 2 192 ? -22.944 7.807 14.186 1.00 38.24 ? 399 ASP B CA 1 ATOM 2884 C C . ASP B 2 192 ? -23.495 6.434 13.828 1.00 39.43 ? 399 ASP B C 1 ATOM 2885 O O . ASP B 2 192 ? -24.245 6.293 12.854 1.00 43.71 ? 399 ASP B O 1 ATOM 2886 C CB . ASP B 2 192 ? -23.567 8.365 15.476 1.00 30.86 ? 399 ASP B CB 1 ATOM 2887 C CG . ASP B 2 192 ? -22.788 7.981 16.733 1.00 35.73 ? 399 ASP B CG 1 ATOM 2888 O OD1 . ASP B 2 192 ? -21.878 7.123 16.661 1.00 33.42 ? 399 ASP B OD1 1 ATOM 2889 O OD2 . ASP B 2 192 ? -23.090 8.545 17.810 1.00 37.35 ? 399 ASP B OD2 1 ATOM 2890 N N . SER B 2 193 ? -23.105 5.425 14.600 1.00 42.62 ? 400 SER B N 1 ATOM 2891 C CA . SER B 2 193 ? -23.471 4.035 14.324 1.00 39.18 ? 400 SER B CA 1 ATOM 2892 C C . SER B 2 193 ? -24.980 3.749 14.407 1.00 35.62 ? 400 SER B C 1 ATOM 2893 O O . SER B 2 193 ? -25.441 2.722 13.906 1.00 27.77 ? 400 SER B O 1 ATOM 2894 C CB . SER B 2 193 ? -22.680 3.093 15.240 1.00 41.80 ? 400 SER B CB 1 ATOM 2895 O OG . SER B 2 193 ? -22.933 3.368 16.610 1.00 39.29 ? 400 SER B OG 1 ATOM 2896 N N . ASP B 2 194 ? -25.748 4.648 15.027 1.00 32.82 ? 401 ASP B N 1 ATOM 2897 C CA . ASP B 2 194 ? -27.208 4.477 15.091 1.00 34.46 ? 401 ASP B CA 1 ATOM 2898 C C . ASP B 2 194 ? -28.003 5.234 14.002 1.00 35.14 ? 401 ASP B C 1 ATOM 2899 O O . ASP B 2 194 ? -29.239 5.194 13.981 1.00 33.04 ? 401 ASP B O 1 ATOM 2900 C CB . ASP B 2 194 ? -27.754 4.803 16.487 1.00 33.03 ? 401 ASP B CB 1 ATOM 2901 C CG . ASP B 2 194 ? -27.558 6.257 16.873 1.00 37.79 ? 401 ASP B CG 1 ATOM 2902 O OD1 . ASP B 2 194 ? -26.777 6.977 16.198 1.00 36.57 ? 401 ASP B OD1 1 ATOM 2903 O OD2 . ASP B 2 194 ? -28.180 6.676 17.874 1.00 40.64 ? 401 ASP B OD2 1 ATOM 2904 N N . GLY B 2 195 ? -27.295 5.907 13.100 1.00 35.46 ? 402 GLY B N 1 ATOM 2905 C CA . GLY B 2 195 ? -27.932 6.598 11.993 1.00 26.21 ? 402 GLY B CA 1 ATOM 2906 C C . GLY B 2 195 ? -28.218 8.057 12.291 1.00 30.95 ? 402 GLY B C 1 ATOM 2907 O O . GLY B 2 195 ? -28.708 8.775 11.428 1.00 25.87 ? 402 GLY B O 1 ATOM 2908 N N . SER B 2 196 ? -27.915 8.490 13.515 1.00 24.73 ? 403 SER B N 1 ATOM 2909 C CA . SER B 2 196 ? -27.987 9.892 13.874 1.00 27.90 ? 403 SER B CA 1 ATOM 2910 C C . SER B 2 196 ? -26.604 10.512 13.708 1.00 31.52 ? 403 SER B C 1 ATOM 2911 O O . SER B 2 196 ? -25.657 9.817 13.313 1.00 32.18 ? 403 SER B O 1 ATOM 2912 C CB . SER B 2 196 ? -28.452 10.040 15.327 1.00 31.61 ? 403 SER B CB 1 ATOM 2913 O OG . SER B 2 196 ? -27.524 9.457 16.223 1.00 23.36 ? 403 SER B OG 1 ATOM 2914 N N . PHE B 2 197 ? -26.495 11.813 13.994 1.00 26.47 ? 404 PHE B N 1 ATOM 2915 C CA . PHE B 2 197 ? -25.228 12.522 13.921 1.00 26.05 ? 404 PHE B CA 1 ATOM 2916 C C . PHE B 2 197 ? -24.824 13.071 15.302 1.00 26.52 ? 404 PHE B C 1 ATOM 2917 O O . PHE B 2 197 ? -25.665 13.259 16.176 1.00 21.06 ? 404 PHE B O 1 ATOM 2918 C CB . PHE B 2 197 ? -25.301 13.689 12.930 1.00 28.58 ? 404 PHE B CB 1 ATOM 2919 C CG . PHE B 2 197 ? -25.491 13.279 11.484 1.00 26.22 ? 404 PHE B CG 1 ATOM 2920 C CD1 . PHE B 2 197 ? -26.757 13.038 10.976 1.00 29.56 ? 404 PHE B CD1 1 ATOM 2921 C CD2 . PHE B 2 197 ? -24.402 13.189 10.626 1.00 29.04 ? 404 PHE B CD2 1 ATOM 2922 C CE1 . PHE B 2 197 ? -26.936 12.687 9.636 1.00 31.71 ? 404 PHE B CE1 1 ATOM 2923 C CE2 . PHE B 2 197 ? -24.566 12.823 9.289 1.00 26.30 ? 404 PHE B CE2 1 ATOM 2924 C CZ . PHE B 2 197 ? -25.837 12.577 8.797 1.00 25.69 ? 404 PHE B CZ 1 ATOM 2925 N N . PHE B 2 198 ? -23.531 13.316 15.477 1.00 24.06 ? 405 PHE B N 1 ATOM 2926 C CA . PHE B 2 198 ? -23.056 14.083 16.613 1.00 28.91 ? 405 PHE B CA 1 ATOM 2927 C C . PHE B 2 198 ? -22.003 15.074 16.143 1.00 31.01 ? 405 PHE B C 1 ATOM 2928 O O . PHE B 2 198 ? -21.515 14.998 15.003 1.00 33.03 ? 405 PHE B O 1 ATOM 2929 C CB . PHE B 2 198 ? -22.495 13.161 17.706 1.00 25.21 ? 405 PHE B CB 1 ATOM 2930 C CG . PHE B 2 198 ? -21.162 12.565 17.373 1.00 25.48 ? 405 PHE B CG 1 ATOM 2931 C CD1 . PHE B 2 198 ? -19.984 13.220 17.713 1.00 27.35 ? 405 PHE B CD1 1 ATOM 2932 C CD2 . PHE B 2 198 ? -21.081 11.343 16.734 1.00 22.36 ? 405 PHE B CD2 1 ATOM 2933 C CE1 . PHE B 2 198 ? -18.752 12.673 17.401 1.00 25.41 ? 405 PHE B CE1 1 ATOM 2934 C CE2 . PHE B 2 198 ? -19.854 10.793 16.417 1.00 19.42 ? 405 PHE B CE2 1 ATOM 2935 C CZ . PHE B 2 198 ? -18.691 11.453 16.749 1.00 24.47 ? 405 PHE B CZ 1 ATOM 2936 N N . LEU B 2 199 ? -21.676 16.012 17.019 1.00 23.75 ? 406 LEU B N 1 ATOM 2937 C CA . LEU B 2 199 ? -20.542 16.898 16.837 1.00 27.48 ? 406 LEU B CA 1 ATOM 2938 C C . LEU B 2 199 ? -20.060 17.333 18.216 1.00 26.69 ? 406 LEU B C 1 ATOM 2939 O O . LEU B 2 199 ? -20.741 17.095 19.210 1.00 26.75 ? 406 LEU B O 1 ATOM 2940 C CB . LEU B 2 199 ? -20.921 18.133 16.001 1.00 29.47 ? 406 LEU B CB 1 ATOM 2941 C CG . LEU B 2 199 ? -21.987 19.154 16.442 1.00 30.20 ? 406 LEU B CG 1 ATOM 2942 C CD1 . LEU B 2 199 ? -21.532 20.059 17.587 1.00 29.78 ? 406 LEU B CD1 1 ATOM 2943 C CD2 . LEU B 2 199 ? -22.377 20.017 15.257 1.00 30.55 ? 406 LEU B CD2 1 ATOM 2944 N N . TYR B 2 200 ? -18.888 17.960 18.256 1.00 28.00 ? 407 TYR B N 1 ATOM 2945 C CA . TYR B 2 200 ? -18.375 18.605 19.459 1.00 35.03 ? 407 TYR B CA 1 ATOM 2946 C C . TYR B 2 200 ? -18.144 20.100 19.194 1.00 40.34 ? 407 TYR B C 1 ATOM 2947 O O . TYR B 2 200 ? -17.697 20.481 18.102 1.00 36.63 ? 407 TYR B O 1 ATOM 2948 C CB . TYR B 2 200 ? -17.047 17.969 19.870 1.00 30.31 ? 407 TYR B CB 1 ATOM 2949 C CG . TYR B 2 200 ? -17.150 16.625 20.551 1.00 30.73 ? 407 TYR B CG 1 ATOM 2950 C CD1 . TYR B 2 200 ? -17.139 16.535 21.942 1.00 29.51 ? 407 TYR B CD1 1 ATOM 2951 C CD2 . TYR B 2 200 ? -17.224 15.441 19.810 1.00 24.75 ? 407 TYR B CD2 1 ATOM 2952 C CE1 . TYR B 2 200 ? -17.207 15.310 22.578 1.00 24.51 ? 407 TYR B CE1 1 ATOM 2953 C CE2 . TYR B 2 200 ? -17.287 14.207 20.440 1.00 27.57 ? 407 TYR B CE2 1 ATOM 2954 C CZ . TYR B 2 200 ? -17.278 14.158 21.831 1.00 23.27 ? 407 TYR B CZ 1 ATOM 2955 O OH . TYR B 2 200 ? -17.354 12.955 22.473 1.00 22.30 ? 407 TYR B OH 1 ATOM 2956 N N . SER B 2 201 ? -18.449 20.936 20.184 1.00 42.11 ? 408 SER B N 1 ATOM 2957 C CA . SER B 2 201 ? -18.087 22.358 20.127 1.00 47.81 ? 408 SER B CA 1 ATOM 2958 C C . SER B 2 201 ? -17.178 22.708 21.293 1.00 45.47 ? 408 SER B C 1 ATOM 2959 O O . SER B 2 201 ? -17.478 22.395 22.454 1.00 46.88 ? 408 SER B O 1 ATOM 2960 C CB . SER B 2 201 ? -19.322 23.270 20.126 1.00 46.74 ? 408 SER B CB 1 ATOM 2961 O OG . SER B 2 201 ? -18.956 24.633 19.909 1.00 35.87 ? 408 SER B OG 1 ATOM 2962 N N . PHE B 2 202 ? -16.063 23.350 20.963 1.00 49.08 ? 409 PHE B N 1 ATOM 2963 C CA . PHE B 2 202 ? -15.056 23.747 21.942 1.00 51.62 ? 409 PHE B CA 1 ATOM 2964 C C . PHE B 2 202 ? -15.001 25.262 22.068 1.00 53.99 ? 409 PHE B C 1 ATOM 2965 O O . PHE B 2 202 ? -14.780 25.966 21.077 1.00 47.41 ? 409 PHE B O 1 ATOM 2966 C CB . PHE B 2 202 ? -13.676 23.224 21.534 1.00 45.28 ? 409 PHE B CB 1 ATOM 2967 C CG . PHE B 2 202 ? -13.580 21.729 21.500 1.00 52.56 ? 409 PHE B CG 1 ATOM 2968 C CD1 . PHE B 2 202 ? -13.179 21.024 22.623 1.00 59.29 ? 409 PHE B CD1 1 ATOM 2969 C CD2 . PHE B 2 202 ? -13.892 21.024 20.344 1.00 48.63 ? 409 PHE B CD2 1 ATOM 2970 C CE1 . PHE B 2 202 ? -13.089 19.643 22.594 1.00 62.03 ? 409 PHE B CE1 1 ATOM 2971 C CE2 . PHE B 2 202 ? -13.800 19.644 20.309 1.00 48.65 ? 409 PHE B CE2 1 ATOM 2972 C CZ . PHE B 2 202 ? -13.398 18.951 21.435 1.00 58.63 ? 409 PHE B CZ 1 ATOM 2973 N N . LEU B 2 203 ? -15.213 25.747 23.287 1.00 52.19 ? 410 LEU B N 1 ATOM 2974 C CA . LEU B 2 203 ? -15.049 27.158 23.607 1.00 54.90 ? 410 LEU B CA 1 ATOM 2975 C C . LEU B 2 203 ? -13.811 27.292 24.480 1.00 62.15 ? 410 LEU B C 1 ATOM 2976 O O . LEU B 2 203 ? -13.773 26.773 25.598 1.00 63.10 ? 410 LEU B O 1 ATOM 2977 C CB . LEU B 2 203 ? -16.281 27.695 24.339 1.00 57.99 ? 410 LEU B CB 1 ATOM 2978 C CG . LEU B 2 203 ? -16.303 29.181 24.710 1.00 64.26 ? 410 LEU B CG 1 ATOM 2979 C CD1 . LEU B 2 203 ? -16.843 30.024 23.567 1.00 64.94 ? 410 LEU B CD1 1 ATOM 2980 C CD2 . LEU B 2 203 ? -17.143 29.395 25.954 1.00 60.55 ? 410 LEU B CD2 1 ATOM 2981 N N . THR B 2 204 ? -12.797 27.973 23.951 1.00 72.92 ? 411 THR B N 1 ATOM 2982 C CA . THR B 2 204 ? -11.538 28.181 24.659 1.00 70.21 ? 411 THR B CA 1 ATOM 2983 C C . THR B 2 204 ? -11.595 29.526 25.372 1.00 79.94 ? 411 THR B C 1 ATOM 2984 O O . THR B 2 204 ? -11.796 30.564 24.736 1.00 86.26 ? 411 THR B O 1 ATOM 2985 C CB . THR B 2 204 ? -10.326 28.120 23.699 1.00 70.37 ? 411 THR B CB 1 ATOM 2986 O OG1 . THR B 2 204 ? -10.381 26.913 22.927 1.00 59.97 ? 411 THR B OG1 1 ATOM 2987 C CG2 . THR B 2 204 ? -9.014 28.144 24.472 1.00 70.65 ? 411 THR B CG2 1 ATOM 2988 N N . VAL B 2 205 ? -11.437 29.499 26.693 1.00 86.58 ? 412 VAL B N 1 ATOM 2989 C CA . VAL B 2 205 ? -11.512 30.715 27.510 1.00 94.19 ? 412 VAL B CA 1 ATOM 2990 C C . VAL B 2 205 ? -10.264 30.927 28.367 1.00 103.29 ? 412 VAL B C 1 ATOM 2991 O O . VAL B 2 205 ? -9.581 29.964 28.731 1.00 105.21 ? 412 VAL B O 1 ATOM 2992 C CB . VAL B 2 205 ? -12.775 30.743 28.411 1.00 89.53 ? 412 VAL B CB 1 ATOM 2993 C CG1 . VAL B 2 205 ? -14.030 30.928 27.572 1.00 86.07 ? 412 VAL B CG1 1 ATOM 2994 C CG2 . VAL B 2 205 ? -12.874 29.492 29.276 1.00 87.26 ? 412 VAL B CG2 1 ATOM 2995 N N . ASP B 2 206 ? -9.977 32.194 28.676 1.00 105.22 ? 413 ASP B N 1 ATOM 2996 C CA . ASP B 2 206 ? -8.888 32.559 29.582 1.00 102.88 ? 413 ASP B CA 1 ATOM 2997 C C . ASP B 2 206 ? -9.112 31.896 30.941 1.00 106.26 ? 413 ASP B C 1 ATOM 2998 O O . ASP B 2 206 ? -10.134 32.132 31.594 1.00 100.58 ? 413 ASP B O 1 ATOM 2999 C CB . ASP B 2 206 ? -8.791 34.082 29.728 1.00 86.39 ? 413 ASP B CB 1 ATOM 3000 N N . LYS B 2 207 ? -8.153 31.061 31.347 1.00 106.82 ? 414 LYS B N 1 ATOM 3001 C CA . LYS B 2 207 ? -8.258 30.234 32.558 1.00 104.02 ? 414 LYS B CA 1 ATOM 3002 C C . LYS B 2 207 ? -8.699 30.996 33.809 1.00 103.59 ? 414 LYS B C 1 ATOM 3003 O O . LYS B 2 207 ? -9.236 30.402 34.745 1.00 106.02 ? 414 LYS B O 1 ATOM 3004 C CB . LYS B 2 207 ? -6.936 29.505 32.830 1.00 96.93 ? 414 LYS B CB 1 ATOM 3005 N N . SER B 2 208 ? -8.468 32.309 33.809 1.00 101.27 ? 415 SER B N 1 ATOM 3006 C CA . SER B 2 208 ? -8.869 33.185 34.908 1.00 99.95 ? 415 SER B CA 1 ATOM 3007 C C . SER B 2 208 ? -10.389 33.247 35.056 1.00 102.91 ? 415 SER B C 1 ATOM 3008 O O . SER B 2 208 ? -10.911 33.163 36.170 1.00 96.11 ? 415 SER B O 1 ATOM 3009 C CB . SER B 2 208 ? -8.303 34.594 34.701 1.00 92.95 ? 415 SER B CB 1 ATOM 3010 N N . ARG B 2 209 ? -11.084 33.376 33.924 1.00 104.07 ? 416 ARG B N 1 ATOM 3011 C CA . ARG B 2 209 ? -12.544 33.514 33.891 1.00 97.70 ? 416 ARG B CA 1 ATOM 3012 C C . ARG B 2 209 ? -13.253 32.298 34.484 1.00 96.58 ? 416 ARG B C 1 ATOM 3013 O O . ARG B 2 209 ? -14.320 32.427 35.090 1.00 94.49 ? 416 ARG B O 1 ATOM 3014 C CB . ARG B 2 209 ? -13.033 33.743 32.457 1.00 95.57 ? 416 ARG B CB 1 ATOM 3015 C CG . ARG B 2 209 ? -12.334 34.870 31.708 1.00 96.59 ? 416 ARG B CG 1 ATOM 3016 C CD . ARG B 2 209 ? -12.839 34.977 30.276 1.00 89.61 ? 416 ARG B CD 1 ATOM 3017 N NE . ARG B 2 209 ? -14.148 35.628 30.200 1.00 92.66 ? 416 ARG B NE 1 ATOM 3018 C CZ . ARG B 2 209 ? -14.893 35.714 29.099 1.00 88.62 ? 416 ARG B CZ 1 ATOM 3019 N NH1 . ARG B 2 209 ? -14.476 35.182 27.956 1.00 79.67 ? 416 ARG B NH1 1 ATOM 3020 N NH2 . ARG B 2 209 ? -16.067 36.333 29.143 1.00 78.04 ? 416 ARG B NH2 1 ATOM 3021 N N . TRP B 2 210 ? -12.642 31.127 34.310 1.00 96.28 ? 417 TRP B N 1 ATOM 3022 C CA . TRP B 2 210 ? -13.214 29.856 34.752 1.00 84.73 ? 417 TRP B CA 1 ATOM 3023 C C . TRP B 2 210 ? -13.291 29.718 36.248 1.00 83.96 ? 417 TRP B C 1 ATOM 3024 O O . TRP B 2 210 ? -14.274 29.193 36.773 1.00 86.06 ? 417 TRP B O 1 ATOM 3025 C CB . TRP B 2 210 ? -12.452 28.685 34.133 1.00 98.57 ? 417 TRP B CB 1 ATOM 3026 C CG . TRP B 2 210 ? -13.094 27.336 34.377 1.00 102.30 ? 417 TRP B CG 1 ATOM 3027 C CD1 . TRP B 2 210 ? -12.512 26.211 34.956 1.00 96.27 ? 417 TRP B CD1 1 ATOM 3028 C CD2 . TRP B 2 210 ? -14.475 26.930 34.063 1.00 100.58 ? 417 TRP B CD2 1 ATOM 3029 N NE1 . TRP B 2 210 ? -13.404 25.171 35.015 1.00 93.49 ? 417 TRP B NE1 1 ATOM 3030 C CE2 . TRP B 2 210 ? -14.599 25.533 34.499 1.00 101.34 ? 417 TRP B CE2 1 ATOM 3031 C CE3 . TRP B 2 210 ? -15.577 27.558 33.486 1.00 90.56 ? 417 TRP B CE3 1 ATOM 3032 C CZ2 . TRP B 2 210 ? -15.782 24.821 34.355 1.00 98.04 ? 417 TRP B CZ2 1 ATOM 3033 C CZ3 . TRP B 2 210 ? -16.763 26.827 33.347 1.00 89.32 ? 417 TRP B CZ3 1 ATOM 3034 C CH2 . TRP B 2 210 ? -16.860 25.492 33.770 1.00 88.72 ? 417 TRP B CH2 1 ATOM 3035 N N . GLN B 2 211 ? -12.258 30.178 36.952 1.00 87.83 ? 418 GLN B N 1 ATOM 3036 C CA . GLN B 2 211 ? -12.307 30.230 38.413 1.00 91.22 ? 418 GLN B CA 1 ATOM 3037 C C . GLN B 2 211 ? -13.144 31.430 38.849 1.00 95.59 ? 418 GLN B C 1 ATOM 3038 O O . GLN B 2 211 ? -13.939 31.329 39.783 1.00 102.41 ? 418 GLN B O 1 ATOM 3039 C CB . GLN B 2 211 ? -10.905 30.313 39.032 1.00 92.57 ? 418 GLN B CB 1 ATOM 3040 C CG . GLN B 2 211 ? -10.043 29.068 38.861 1.00 91.29 ? 418 GLN B CG 1 ATOM 3041 C CD . GLN B 2 211 ? -9.110 29.146 37.660 1.00 93.60 ? 418 GLN B CD 1 ATOM 3042 O OE1 . GLN B 2 211 ? -8.955 28.174 36.921 1.00 97.85 ? 418 GLN B OE1 1 ATOM 3043 N NE2 . GLN B 2 211 ? -8.483 30.303 37.462 1.00 82.12 ? 418 GLN B NE2 1 ATOM 3044 N N . GLN B 2 212 ? -12.962 32.556 38.158 1.00 94.75 ? 419 GLN B N 1 ATOM 3045 C CA . GLN B 2 212 ? -13.694 33.788 38.453 1.00 91.03 ? 419 GLN B CA 1 ATOM 3046 C C . GLN B 2 212 ? -15.138 33.696 37.970 1.00 99.13 ? 419 GLN B C 1 ATOM 3047 O O . GLN B 2 212 ? -16.017 33.209 38.695 1.00 102.54 ? 419 GLN B O 1 ATOM 3048 C CB . GLN B 2 212 ? -13.001 34.998 37.815 1.00 74.83 ? 419 GLN B CB 1 ATOM 3049 N N . ASN B 2 214 ? -17.776 32.526 36.459 1.00 64.14 ? 421 ASN B N 1 ATOM 3050 C CA . ASN B 2 214 ? -18.828 32.911 35.525 1.00 75.14 ? 421 ASN B CA 1 ATOM 3051 C C . ASN B 2 214 ? -19.562 31.701 34.946 1.00 77.02 ? 421 ASN B C 1 ATOM 3052 O O . ASN B 2 214 ? -18.949 30.667 34.676 1.00 80.62 ? 421 ASN B O 1 ATOM 3053 C CB . ASN B 2 214 ? -18.245 33.766 34.395 1.00 75.91 ? 421 ASN B CB 1 ATOM 3054 N N . VAL B 2 215 ? -20.875 31.838 34.764 1.00 63.25 ? 422 VAL B N 1 ATOM 3055 C CA . VAL B 2 215 ? -21.702 30.791 34.161 1.00 53.89 ? 422 VAL B CA 1 ATOM 3056 C C . VAL B 2 215 ? -21.620 30.879 32.627 1.00 55.21 ? 422 VAL B C 1 ATOM 3057 O O . VAL B 2 215 ? -21.839 31.941 32.050 1.00 55.59 ? 422 VAL B O 1 ATOM 3058 C CB . VAL B 2 215 ? -23.174 30.880 34.648 1.00 52.45 ? 422 VAL B CB 1 ATOM 3059 C CG1 . VAL B 2 215 ? -24.035 29.797 34.011 1.00 53.41 ? 422 VAL B CG1 1 ATOM 3060 C CG2 . VAL B 2 215 ? -23.251 30.783 36.169 1.00 59.59 ? 422 VAL B CG2 1 ATOM 3061 N N . PHE B 2 216 ? -21.294 29.759 31.983 1.00 55.78 ? 423 PHE B N 1 ATOM 3062 C CA . PHE B 2 216 ? -21.124 29.694 30.525 1.00 54.42 ? 423 PHE B CA 1 ATOM 3063 C C . PHE B 2 216 ? -22.147 28.779 29.855 1.00 51.11 ? 423 PHE B C 1 ATOM 3064 O O . PHE B 2 216 ? -22.410 27.675 30.337 1.00 45.81 ? 423 PHE B O 1 ATOM 3065 C CB . PHE B 2 216 ? -19.724 29.196 30.178 1.00 60.18 ? 423 PHE B CB 1 ATOM 3066 C CG . PHE B 2 216 ? -18.667 30.258 30.234 1.00 61.82 ? 423 PHE B CG 1 ATOM 3067 C CD1 . PHE B 2 216 ? -18.075 30.610 31.444 1.00 61.57 ? 423 PHE B CD1 1 ATOM 3068 C CD2 . PHE B 2 216 ? -18.247 30.895 29.071 1.00 55.75 ? 423 PHE B CD2 1 ATOM 3069 C CE1 . PHE B 2 216 ? -17.091 31.586 31.494 1.00 66.50 ? 423 PHE B CE1 1 ATOM 3070 C CE2 . PHE B 2 216 ? -17.264 31.871 29.112 1.00 62.23 ? 423 PHE B CE2 1 ATOM 3071 C CZ . PHE B 2 216 ? -16.685 32.218 30.326 1.00 65.86 ? 423 PHE B CZ 1 ATOM 3072 N N . SER B 2 217 ? -22.691 29.228 28.725 1.00 46.75 ? 424 SER B N 1 ATOM 3073 C CA . SER B 2 217 ? -23.793 28.520 28.073 1.00 49.34 ? 424 SER B CA 1 ATOM 3074 C C . SER B 2 217 ? -23.515 28.081 26.639 1.00 49.12 ? 424 SER B C 1 ATOM 3075 O O . SER B 2 217 ? -22.892 28.807 25.866 1.00 49.68 ? 424 SER B O 1 ATOM 3076 C CB . SER B 2 217 ? -25.084 29.341 28.142 1.00 51.93 ? 424 SER B CB 1 ATOM 3077 O OG . SER B 2 217 ? -25.641 29.296 29.449 1.00 59.55 ? 424 SER B OG 1 ATOM 3078 N N . CYS B 2 218 ? -23.990 26.880 26.312 1.00 46.72 ? 425 CYS B N 1 ATOM 3079 C CA . CYS B 2 218 ? -23.901 26.301 24.976 1.00 42.79 ? 425 CYS B CA 1 ATOM 3080 C C . CYS B 2 218 ? -25.306 26.223 24.392 1.00 41.19 ? 425 CYS B C 1 ATOM 3081 O O . CYS B 2 218 ? -26.208 25.631 24.999 1.00 45.52 ? 425 CYS B O 1 ATOM 3082 C CB . CYS B 2 218 ? -23.286 24.894 25.050 1.00 43.91 ? 425 CYS B CB 1 ATOM 3083 S SG . CYS B 2 218 ? -23.453 23.931 23.529 1.00 53.54 ? 425 CYS B SG 1 ATOM 3084 N N . SER B 2 219 ? -25.490 26.815 23.218 1.00 42.59 ? 426 SER B N 1 ATOM 3085 C CA . SER B 2 219 ? -26.818 26.934 22.607 1.00 48.98 ? 426 SER B CA 1 ATOM 3086 C C . SER B 2 219 ? -26.917 26.129 21.333 1.00 41.61 ? 426 SER B C 1 ATOM 3087 O O . SER B 2 219 ? -26.022 26.162 20.494 1.00 40.69 ? 426 SER B O 1 ATOM 3088 C CB . SER B 2 219 ? -27.162 28.399 22.315 1.00 49.52 ? 426 SER B CB 1 ATOM 3089 O OG . SER B 2 219 ? -27.430 29.101 23.515 1.00 56.21 ? 426 SER B OG 1 ATOM 3090 N N . VAL B 2 220 ? -28.017 25.405 21.190 1.00 44.97 ? 427 VAL B N 1 ATOM 3091 C CA . VAL B 2 220 ? -28.195 24.534 20.035 1.00 48.82 ? 427 VAL B CA 1 ATOM 3092 C C . VAL B 2 220 ? -29.523 24.819 19.351 1.00 43.19 ? 427 VAL B C 1 ATOM 3093 O O . VAL B 2 220 ? -30.565 24.956 20.006 1.00 44.47 ? 427 VAL B O 1 ATOM 3094 C CB . VAL B 2 220 ? -28.100 23.043 20.428 1.00 43.07 ? 427 VAL B CB 1 ATOM 3095 C CG1 . VAL B 2 220 ? -28.330 22.148 19.219 1.00 45.43 ? 427 VAL B CG1 1 ATOM 3096 C CG2 . VAL B 2 220 ? -26.745 22.748 21.050 1.00 39.87 ? 427 VAL B CG2 1 ATOM 3097 N N . MET B 2 221 ? -29.475 24.918 18.030 1.00 40.92 ? 428 MET B N 1 ATOM 3098 C CA . MET B 2 221 ? -30.684 25.113 17.246 1.00 43.79 ? 428 MET B CA 1 ATOM 3099 C C . MET B 2 221 ? -30.841 23.974 16.269 1.00 37.95 ? 428 MET B C 1 ATOM 3100 O O . MET B 2 221 ? -29.948 23.704 15.476 1.00 35.86 ? 428 MET B O 1 ATOM 3101 C CB . MET B 2 221 ? -30.665 26.454 16.518 1.00 47.55 ? 428 MET B CB 1 ATOM 3102 C CG . MET B 2 221 ? -30.477 27.636 17.455 1.00 55.43 ? 428 MET B CG 1 ATOM 3103 S SD . MET B 2 221 ? -31.062 29.187 16.774 1.00 75.84 ? 428 MET B SD 1 ATOM 3104 C CE . MET B 2 221 ? -30.024 29.333 15.326 1.00 53.48 ? 428 MET B CE 1 ATOM 3105 N N . HIS B 2 222 ? -31.987 23.308 16.353 1.00 39.35 ? 429 HIS B N 1 ATOM 3106 C CA . HIS B 2 222 ? -32.271 22.128 15.567 1.00 35.99 ? 429 HIS B CA 1 ATOM 3107 C C . HIS B 2 222 ? -33.752 21.893 15.570 1.00 41.22 ? 429 HIS B C 1 ATOM 3108 O O . HIS B 2 222 ? -34.413 22.054 16.602 1.00 42.91 ? 429 HIS B O 1 ATOM 3109 C CB . HIS B 2 222 ? -31.533 20.919 16.145 1.00 33.29 ? 429 HIS B CB 1 ATOM 3110 C CG . HIS B 2 222 ? -31.652 19.679 15.301 1.00 32.19 ? 429 HIS B CG 1 ATOM 3111 N ND1 . HIS B 2 222 ? -32.718 18.856 15.370 1.00 31.88 ? 429 HIS B ND1 1 ATOM 3112 C CD2 . HIS B 2 222 ? -30.808 19.154 14.327 1.00 32.42 ? 429 HIS B CD2 1 ATOM 3113 C CE1 . HIS B 2 222 ? -32.559 17.846 14.493 1.00 30.83 ? 429 HIS B CE1 1 ATOM 3114 N NE2 . HIS B 2 222 ? -31.390 18.030 13.855 1.00 34.96 ? 429 HIS B NE2 1 ATOM 3115 N N . GLU B 2 223 ? -34.285 21.491 14.418 1.00 37.08 ? 430 GLU B N 1 ATOM 3116 C CA . GLU B 2 223 ? -35.735 21.381 14.234 1.00 38.72 ? 430 GLU B CA 1 ATOM 3117 C C . GLU B 2 223 ? -36.458 20.517 15.272 1.00 37.37 ? 430 GLU B C 1 ATOM 3118 O O . GLU B 2 223 ? -37.601 20.802 15.622 1.00 44.34 ? 430 GLU B O 1 ATOM 3119 C CB . GLU B 2 223 ? -36.061 20.884 12.824 1.00 39.13 ? 430 GLU B CB 1 ATOM 3120 C CG . GLU B 2 223 ? -35.515 19.501 12.523 1.00 41.52 ? 430 GLU B CG 1 ATOM 3121 C CD . GLU B 2 223 ? -36.175 18.870 11.323 1.00 49.03 ? 430 GLU B CD 1 ATOM 3122 O OE1 . GLU B 2 223 ? -35.485 18.693 10.300 1.00 51.78 ? 430 GLU B OE1 1 ATOM 3123 O OE2 . GLU B 2 223 ? -37.386 18.569 11.400 1.00 57.10 ? 430 GLU B OE2 1 ATOM 3124 N N . ALA B 2 224 ? -35.793 19.472 15.759 1.00 33.59 ? 431 ALA B N 1 ATOM 3125 C CA . ALA B 2 224 ? -36.413 18.506 16.664 1.00 31.99 ? 431 ALA B CA 1 ATOM 3126 C C . ALA B 2 224 ? -36.314 18.881 18.151 1.00 39.41 ? 431 ALA B C 1 ATOM 3127 O O . ALA B 2 224 ? -36.726 18.108 19.020 1.00 45.55 ? 431 ALA B O 1 ATOM 3128 C CB . ALA B 2 224 ? -35.846 17.114 16.423 1.00 39.91 ? 431 ALA B CB 1 ATOM 3129 N N . LEU B 2 225 ? -35.778 20.065 18.433 1.00 39.23 ? 432 LEU B N 1 ATOM 3130 C CA . LEU B 2 225 ? -35.809 20.617 19.787 1.00 51.48 ? 432 LEU B CA 1 ATOM 3131 C C . LEU B 2 225 ? -37.155 21.282 20.055 1.00 45.83 ? 432 LEU B C 1 ATOM 3132 O O . LEU B 2 225 ? -37.935 21.491 19.134 1.00 54.05 ? 432 LEU B O 1 ATOM 3133 C CB . LEU B 2 225 ? -34.671 21.624 19.975 1.00 44.44 ? 432 LEU B CB 1 ATOM 3134 C CG . LEU B 2 225 ? -33.291 21.014 20.230 1.00 51.25 ? 432 LEU B CG 1 ATOM 3135 C CD1 . LEU B 2 225 ? -32.201 22.062 20.056 1.00 45.02 ? 432 LEU B CD1 1 ATOM 3136 C CD2 . LEU B 2 225 ? -33.213 20.358 21.608 1.00 44.13 ? 432 LEU B CD2 1 ATOM 3137 N N . HIS B 2 226 ? -37.427 21.606 21.314 1.00 56.02 ? 433 HIS B N 1 ATOM 3138 C CA . HIS B 2 226 ? -38.627 22.367 21.665 1.00 61.20 ? 433 HIS B CA 1 ATOM 3139 C C . HIS B 2 226 ? -38.379 23.820 21.371 1.00 62.35 ? 433 HIS B C 1 ATOM 3140 O O . HIS B 2 226 ? -37.422 24.409 21.880 1.00 62.49 ? 433 HIS B O 1 ATOM 3141 C CB . HIS B 2 226 ? -38.990 22.153 23.130 1.00 65.88 ? 433 HIS B CB 1 ATOM 3142 C CG . HIS B 2 226 ? -40.337 22.715 23.512 1.00 82.48 ? 433 HIS B CG 1 ATOM 3143 N ND1 . HIS B 2 226 ? -41.494 22.108 23.184 1.00 83.71 ? 433 HIS B ND1 1 ATOM 3144 C CD2 . HIS B 2 226 ? -40.683 23.866 24.220 1.00 89.49 ? 433 HIS B CD2 1 ATOM 3145 C CE1 . HIS B 2 226 ? -42.529 22.833 23.653 1.00 87.26 ? 433 HIS B CE1 1 ATOM 3146 N NE2 . HIS B 2 226 ? -42.031 23.908 24.287 1.00 96.25 ? 433 HIS B NE2 1 ATOM 3147 N N . ASN B 2 227 ? -39.231 24.404 20.527 1.00 66.12 ? 434 ASN B N 1 ATOM 3148 C CA . ASN B 2 227 ? -39.014 25.753 19.972 1.00 63.47 ? 434 ASN B CA 1 ATOM 3149 C C . ASN B 2 227 ? -37.771 25.818 19.092 1.00 51.02 ? 434 ASN B C 1 ATOM 3150 O O . ASN B 2 227 ? -37.260 26.900 18.804 1.00 46.33 ? 434 ASN B O 1 ATOM 3151 C CB . ASN B 2 227 ? -38.926 26.823 21.071 1.00 61.88 ? 434 ASN B CB 1 ATOM 3152 C CG . ASN B 2 227 ? -40.205 26.953 21.871 1.00 73.33 ? 434 ASN B CG 1 ATOM 3153 O OD1 . ASN B 2 227 ? -41.308 26.878 21.323 1.00 77.77 ? 434 ASN B OD1 1 ATOM 3154 N ND2 . ASN B 2 227 ? -40.063 27.157 23.182 1.00 59.64 ? 434 ASN B ND2 1 ATOM 3155 N N . ALA B 2 228 ? -37.292 24.646 18.677 1.00 46.78 ? 435 ALA B N 1 ATOM 3156 C CA . ALA B 2 228 ? -36.072 24.513 17.876 1.00 41.99 ? 435 ALA B CA 1 ATOM 3157 C C . ALA B 2 228 ? -34.877 25.155 18.563 1.00 34.73 ? 435 ALA B C 1 ATOM 3158 O O . ALA B 2 228 ? -33.965 25.650 17.906 1.00 33.25 ? 435 ALA B O 1 ATOM 3159 C CB . ALA B 2 228 ? -36.275 25.080 16.472 1.00 47.88 ? 435 ALA B CB 1 ATOM 3160 N N . TYR B 2 229 ? -34.880 25.136 19.895 1.00 34.11 ? 436 TYR B N 1 ATOM 3161 C CA . TYR B 2 229 ? -33.849 25.810 20.657 1.00 36.70 ? 436 TYR B CA 1 ATOM 3162 C C . TYR B 2 229 ? -33.685 25.219 22.046 1.00 43.01 ? 436 TYR B C 1 ATOM 3163 O O . TYR B 2 229 ? -34.662 24.960 22.746 1.00 37.88 ? 436 TYR B O 1 ATOM 3164 C CB . TYR B 2 229 ? -34.152 27.311 20.769 1.00 38.17 ? 436 TYR B CB 1 ATOM 3165 C CG . TYR B 2 229 ? -33.076 28.099 21.485 1.00 34.16 ? 436 TYR B CG 1 ATOM 3166 C CD1 . TYR B 2 229 ? -33.147 28.317 22.870 1.00 37.96 ? 436 TYR B CD1 1 ATOM 3167 C CD2 . TYR B 2 229 ? -31.990 28.624 20.787 1.00 36.04 ? 436 TYR B CD2 1 ATOM 3168 C CE1 . TYR B 2 229 ? -32.167 29.036 23.535 1.00 38.31 ? 436 TYR B CE1 1 ATOM 3169 C CE2 . TYR B 2 229 ? -30.999 29.348 21.442 1.00 46.07 ? 436 TYR B CE2 1 ATOM 3170 C CZ . TYR B 2 229 ? -31.093 29.551 22.815 1.00 46.48 ? 436 TYR B CZ 1 ATOM 3171 O OH . TYR B 2 229 ? -30.116 30.263 23.475 1.00 53.88 ? 436 TYR B OH 1 ATOM 3172 N N . THR B 2 230 ? -32.428 25.014 22.431 1.00 43.56 ? 437 THR B N 1 ATOM 3173 C CA . THR B 2 230 ? -32.094 24.625 23.787 1.00 46.31 ? 437 THR B CA 1 ATOM 3174 C C . THR B 2 230 ? -30.773 25.267 24.186 1.00 46.97 ? 437 THR B C 1 ATOM 3175 O O . THR B 2 230 ? -29.982 25.682 23.332 1.00 46.42 ? 437 THR B O 1 ATOM 3176 C CB . THR B 2 230 ? -32.050 23.088 23.961 1.00 44.20 ? 437 THR B CB 1 ATOM 3177 O OG1 . THR B 2 230 ? -32.228 22.759 25.345 1.00 43.70 ? 437 THR B OG1 1 ATOM 3178 C CG2 . THR B 2 230 ? -30.735 22.501 23.450 1.00 43.99 ? 437 THR B CG2 1 ATOM 3179 N N . GLN B 2 231 ? -30.556 25.351 25.492 1.00 47.67 ? 438 GLN B N 1 ATOM 3180 C CA . GLN B 2 231 ? -29.380 25.984 26.045 1.00 50.37 ? 438 GLN B CA 1 ATOM 3181 C C . GLN B 2 231 ? -28.942 25.197 27.268 1.00 49.66 ? 438 GLN B C 1 ATOM 3182 O O . GLN B 2 231 ? -29.765 24.884 28.130 1.00 54.99 ? 438 GLN B O 1 ATOM 3183 C CB . GLN B 2 231 ? -29.712 27.421 26.437 1.00 49.93 ? 438 GLN B CB 1 ATOM 3184 C CG . GLN B 2 231 ? -28.504 28.313 26.666 1.00 54.08 ? 438 GLN B CG 1 ATOM 3185 C CD . GLN B 2 231 ? -28.899 29.729 27.042 1.00 51.76 ? 438 GLN B CD 1 ATOM 3186 O OE1 . GLN B 2 231 ? -29.942 29.954 27.655 1.00 62.36 ? 438 GLN B OE1 1 ATOM 3187 N NE2 . GLN B 2 231 ? -28.067 30.692 26.672 1.00 45.32 ? 438 GLN B NE2 1 ATOM 3188 N N . LYS B 2 232 ? -27.652 24.868 27.333 1.00 46.99 ? 439 LYS B N 1 ATOM 3189 C CA . LYS B 2 232 ? -27.082 24.196 28.501 1.00 41.47 ? 439 LYS B CA 1 ATOM 3190 C C . LYS B 2 232 ? -25.989 25.058 29.102 1.00 44.56 ? 439 LYS B C 1 ATOM 3191 O O . LYS B 2 232 ? -25.206 25.668 28.375 1.00 43.43 ? 439 LYS B O 1 ATOM 3192 C CB . LYS B 2 232 ? -26.533 22.813 28.139 1.00 38.20 ? 439 LYS B CB 1 ATOM 3193 C CG . LYS B 2 232 ? -27.580 21.823 27.664 1.00 44.57 ? 439 LYS B CG 1 ATOM 3194 C CD . LYS B 2 232 ? -28.438 21.269 28.787 1.00 49.14 ? 439 LYS B CD 1 ATOM 3195 C CE . LYS B 2 232 ? -29.532 20.374 28.226 1.00 57.50 ? 439 LYS B CE 1 ATOM 3196 N NZ . LYS B 2 232 ? -30.132 19.527 29.292 1.00 78.45 ? 439 LYS B NZ 1 ATOM 3197 N N . SER B 2 233 ? -25.950 25.115 30.431 1.00 51.58 ? 440 SER B N 1 ATOM 3198 C CA . SER B 2 233 ? -24.996 25.972 31.132 1.00 57.83 ? 440 SER B CA 1 ATOM 3199 C C . SER B 2 233 ? -23.937 25.204 31.917 1.00 64.06 ? 440 SER B C 1 ATOM 3200 O O . SER B 2 233 ? -24.146 24.056 32.309 1.00 71.31 ? 440 SER B O 1 ATOM 3201 C CB . SER B 2 233 ? -25.712 27.004 32.015 1.00 62.66 ? 440 SER B CB 1 ATOM 3202 O OG . SER B 2 233 ? -27.062 26.647 32.245 1.00 72.53 ? 440 SER B OG 1 ATOM 3203 N N . LEU B 2 234 ? -22.801 25.858 32.145 1.00 67.18 ? 441 LEU B N 1 ATOM 3204 C CA . LEU B 2 234 ? -21.624 25.214 32.707 1.00 64.55 ? 441 LEU B CA 1 ATOM 3205 C C . LEU B 2 234 ? -20.803 26.202 33.530 1.00 66.20 ? 441 LEU B C 1 ATOM 3206 O O . LEU B 2 234 ? -20.481 27.295 33.053 1.00 63.79 ? 441 LEU B O 1 ATOM 3207 C CB . LEU B 2 234 ? -20.776 24.639 31.566 1.00 65.85 ? 441 LEU B CB 1 ATOM 3208 C CG . LEU B 2 234 ? -19.549 23.775 31.863 1.00 72.35 ? 441 LEU B CG 1 ATOM 3209 C CD1 . LEU B 2 234 ? -19.919 22.470 32.559 1.00 79.08 ? 441 LEU B CD1 1 ATOM 3210 C CD2 . LEU B 2 234 ? -18.806 23.500 30.567 1.00 75.01 ? 441 LEU B CD2 1 ATOM 3211 N N . SER B 2 235 ? -20.472 25.811 34.762 1.00 68.64 ? 442 SER B N 1 ATOM 3212 C CA . SER B 2 235 ? -19.637 26.623 35.654 1.00 75.19 ? 442 SER B CA 1 ATOM 3213 C C . SER B 2 235 ? -18.901 25.762 36.680 1.00 85.76 ? 442 SER B C 1 ATOM 3214 O O . SER B 2 235 ? -19.298 24.626 36.944 1.00 98.85 ? 442 SER B O 1 ATOM 3215 C CB . SER B 2 235 ? -20.468 27.704 36.361 1.00 79.80 ? 442 SER B CB 1 ATOM 3216 O OG . SER B 2 235 ? -21.208 27.172 37.446 1.00 83.37 ? 442 SER B OG 1 ATOM 3217 N N . LEU B 2 236 ? -17.829 26.309 37.253 1.00 89.16 ? 443 LEU B N 1 ATOM 3218 C CA . LEU B 2 236 ? -17.081 25.625 38.307 1.00 87.25 ? 443 LEU B CA 1 ATOM 3219 C C . LEU B 2 236 ? -17.757 25.848 39.656 1.00 70.40 ? 443 LEU B C 1 ATOM 3220 O O . LEU B 2 236 ? -18.438 24.963 40.169 1.00 60.66 ? 443 LEU B O 1 ATOM 3221 C CB . LEU B 2 236 ? -15.624 26.108 38.343 1.00 98.83 ? 443 LEU B CB 1 ATOM 3222 C CG . LEU B 2 236 ? -14.582 25.257 39.089 1.00 98.27 ? 443 LEU B CG 1 ATOM 3223 C CD1 . LEU B 2 236 ? -13.206 25.407 38.457 1.00 91.84 ? 443 LEU B CD1 1 ATOM 3224 C CD2 . LEU B 2 236 ? -14.524 25.578 40.580 1.00 100.52 ? 443 LEU B CD2 1 ATOM 3225 N N . ASP C 3 1 ? 13.770 4.567 25.714 1.00 47.72 ? 1 ASP C N 1 ATOM 3226 C CA . ASP C 3 1 ? 12.684 3.569 25.897 1.00 49.02 ? 1 ASP C CA 1 ATOM 3227 C C . ASP C 3 1 ? 11.819 3.421 24.638 1.00 47.21 ? 1 ASP C C 1 ATOM 3228 O O . ASP C 3 1 ? 12.073 4.067 23.612 1.00 40.43 ? 1 ASP C O 1 ATOM 3229 C CB . ASP C 3 1 ? 11.826 3.918 27.124 1.00 51.91 ? 1 ASP C CB 1 ATOM 3230 C CG . ASP C 3 1 ? 11.253 5.341 27.080 1.00 59.76 ? 1 ASP C CG 1 ATOM 3231 O OD1 . ASP C 3 1 ? 10.795 5.807 28.143 1.00 53.51 ? 1 ASP C OD1 1 ATOM 3232 O OD2 . ASP C 3 1 ? 11.248 5.995 26.010 1.00 52.74 ? 1 ASP C OD2 1 ATOM 3233 N N . CYS C 3 2 ? 10.796 2.577 24.735 1.00 42.06 ? 2 CYS C N 1 ATOM 3234 C CA . CYS C 3 2 ? 9.951 2.237 23.599 1.00 43.20 ? 2 CYS C CA 1 ATOM 3235 C C . CYS C 3 2 ? 8.474 2.383 23.929 1.00 45.86 ? 2 CYS C C 1 ATOM 3236 O O . CYS C 3 2 ? 8.088 2.467 25.110 1.00 40.48 ? 2 CYS C O 1 ATOM 3237 C CB . CYS C 3 2 ? 10.221 0.798 23.157 1.00 39.95 ? 2 CYS C CB 1 ATOM 3238 S SG . CYS C 3 2 ? 11.911 0.501 22.606 1.00 52.53 ? 2 CYS C SG 1 ATOM 3239 N N . ALA C 3 3 ? 7.658 2.401 22.873 1.00 33.24 ? 3 ALA C N 1 ATOM 3240 C CA . ALA C 3 3 ? 6.213 2.416 23.004 1.00 28.58 ? 3 ALA C CA 1 ATOM 3241 C C . ALA C 3 3 ? 5.583 1.257 22.258 1.00 36.50 ? 3 ALA C C 1 ATOM 3242 O O . ALA C 3 3 ? 6.000 0.896 21.147 1.00 24.46 ? 3 ALA C O 1 ATOM 3243 C CB . ALA C 3 3 ? 5.648 3.734 22.514 1.00 25.23 ? 3 ALA C CB 1 ATOM 3244 N N . TRP C 3 4 ? 4.560 0.692 22.885 1.00 35.51 ? 4 TRP C N 1 ATOM 3245 C CA . TRP C 3 4 ? 3.822 -0.435 22.341 1.00 39.37 ? 4 TRP C CA 1 ATOM 3246 C C . TRP C 3 4 ? 2.362 -0.099 22.170 1.00 38.22 ? 4 TRP C C 1 ATOM 3247 O O . TRP C 3 4 ? 1.800 0.709 22.907 1.00 31.44 ? 4 TRP C O 1 ATOM 3248 C CB . TRP C 3 4 ? 4.003 -1.659 23.242 1.00 38.71 ? 4 TRP C CB 1 ATOM 3249 C CG . TRP C 3 4 ? 5.443 -2.104 23.342 1.00 36.02 ? 4 TRP C CG 1 ATOM 3250 C CD1 . TRP C 3 4 ? 6.439 -1.591 24.180 1.00 35.90 ? 4 TRP C CD1 1 ATOM 3251 C CD2 . TRP C 3 4 ? 6.108 -3.154 22.561 1.00 36.93 ? 4 TRP C CD2 1 ATOM 3252 N NE1 . TRP C 3 4 ? 7.630 -2.237 23.977 1.00 39.19 ? 4 TRP C NE1 1 ATOM 3253 C CE2 . TRP C 3 4 ? 7.502 -3.191 23.024 1.00 40.73 ? 4 TRP C CE2 1 ATOM 3254 C CE3 . TRP C 3 4 ? 5.703 -4.041 21.574 1.00 45.86 ? 4 TRP C CE3 1 ATOM 3255 C CZ2 . TRP C 3 4 ? 8.426 -4.085 22.504 1.00 45.42 ? 4 TRP C CZ2 1 ATOM 3256 C CZ3 . TRP C 3 4 ? 6.647 -4.940 21.054 1.00 51.50 ? 4 TRP C CZ3 1 ATOM 3257 C CH2 . TRP C 3 4 ? 7.975 -4.957 21.507 1.00 48.79 ? 4 TRP C CH2 1 ATOM 3258 N N . HIS C 3 5 ? 1.740 -0.692 21.161 1.00 39.03 ? 5 HIS C N 1 ATOM 3259 C CA . HIS C 3 5 ? 0.323 -0.491 20.934 1.00 36.66 ? 5 HIS C CA 1 ATOM 3260 C C . HIS C 3 5 ? -0.338 -1.793 20.643 1.00 39.88 ? 5 HIS C C 1 ATOM 3261 O O . HIS C 3 5 ? -0.133 -2.370 19.570 1.00 40.37 ? 5 HIS C O 1 ATOM 3262 C CB . HIS C 3 5 ? 0.094 0.477 19.791 1.00 39.45 ? 5 HIS C CB 1 ATOM 3263 C CG . HIS C 3 5 ? -1.359 0.666 19.457 1.00 38.88 ? 5 HIS C CG 1 ATOM 3264 N ND1 . HIS C 3 5 ? -2.205 1.302 20.276 1.00 37.04 ? 5 HIS C ND1 1 ATOM 3265 C CD2 . HIS C 3 5 ? -2.102 0.261 18.359 1.00 40.72 ? 5 HIS C CD2 1 ATOM 3266 C CE1 . HIS C 3 5 ? -3.430 1.316 19.729 1.00 37.41 ? 5 HIS C CE1 1 ATOM 3267 N NE2 . HIS C 3 5 ? -3.365 0.679 18.554 1.00 45.30 ? 5 HIS C NE2 1 ATOM 3268 N N . LEU C 3 6 ? -1.147 -2.260 21.597 1.00 48.27 ? 6 LEU C N 1 ATOM 3269 C CA . LEU C 3 6 ? -1.748 -3.597 21.547 1.00 47.15 ? 6 LEU C CA 1 ATOM 3270 C C . LEU C 3 6 ? -0.661 -4.636 21.247 1.00 37.84 ? 6 LEU C C 1 ATOM 3271 O O . LEU C 3 6 ? -0.842 -5.522 20.418 1.00 37.82 ? 6 LEU C O 1 ATOM 3272 C CB . LEU C 3 6 ? -2.897 -3.664 20.521 1.00 48.65 ? 6 LEU C CB 1 ATOM 3273 C CG . LEU C 3 6 ? -4.047 -2.646 20.635 1.00 58.14 ? 6 LEU C CG 1 ATOM 3274 C CD1 . LEU C 3 6 ? -4.852 -2.589 19.345 1.00 61.39 ? 6 LEU C CD1 1 ATOM 3275 C CD2 . LEU C 3 6 ? -4.960 -2.940 21.820 1.00 59.02 ? 6 LEU C CD2 1 ATOM 3276 N N . GLY C 3 7 ? 0.479 -4.484 21.917 1.00 46.43 ? 7 GLY C N 1 ATOM 3277 C CA . GLY C 3 7 ? 1.612 -5.403 21.794 1.00 47.81 ? 7 GLY C CA 1 ATOM 3278 C C . GLY C 3 7 ? 2.457 -5.304 20.533 1.00 46.05 ? 7 GLY C C 1 ATOM 3279 O O . GLY C 3 7 ? 3.260 -6.192 20.262 1.00 44.49 ? 7 GLY C O 1 ATOM 3280 N N . GLU C 3 8 ? 2.277 -4.234 19.761 1.00 48.36 ? 8 GLU C N 1 ATOM 3281 C CA . GLU C 3 8 ? 3.049 -4.009 18.535 1.00 40.42 ? 8 GLU C CA 1 ATOM 3282 C C . GLU C 3 8 ? 4.015 -2.855 18.740 1.00 38.49 ? 8 GLU C C 1 ATOM 3283 O O . GLU C 3 8 ? 3.642 -1.825 19.305 1.00 42.49 ? 8 GLU C O 1 ATOM 3284 C CB . GLU C 3 8 ? 2.113 -3.672 17.381 1.00 45.53 ? 8 GLU C CB 1 ATOM 3285 C CG . GLU C 3 8 ? 2.031 -4.697 16.267 1.00 55.01 ? 8 GLU C CG 1 ATOM 3286 C CD . GLU C 3 8 ? 1.744 -4.042 14.922 1.00 63.40 ? 8 GLU C CD 1 ATOM 3287 O OE1 . GLU C 3 8 ? 0.607 -3.569 14.713 1.00 74.31 ? 8 GLU C OE1 1 ATOM 3288 O OE2 . GLU C 3 8 ? 2.659 -3.989 14.072 1.00 65.26 ? 8 GLU C OE2 1 ATOM 3289 N N . LEU C 3 9 ? 5.249 -3.012 18.274 1.00 33.79 ? 9 LEU C N 1 ATOM 3290 C CA . LEU C 3 9 ? 6.244 -1.951 18.430 1.00 35.05 ? 9 LEU C CA 1 ATOM 3291 C C . LEU C 3 9 ? 5.845 -0.653 17.703 1.00 34.59 ? 9 LEU C C 1 ATOM 3292 O O . LEU C 3 9 ? 5.552 -0.656 16.487 1.00 25.19 ? 9 LEU C O 1 ATOM 3293 C CB . LEU C 3 9 ? 7.646 -2.427 17.994 1.00 31.74 ? 9 LEU C CB 1 ATOM 3294 C CG . LEU C 3 9 ? 8.821 -1.535 18.417 1.00 30.07 ? 9 LEU C CG 1 ATOM 3295 C CD1 . LEU C 3 9 ? 8.805 -1.269 19.923 1.00 25.17 ? 9 LEU C CD1 1 ATOM 3296 C CD2 . LEU C 3 9 ? 10.168 -2.121 17.988 1.00 28.40 ? 9 LEU C CD2 1 ATOM 3297 N N . VAL C 3 10 ? 5.806 0.444 18.457 1.00 21.33 ? 10 VAL C N 1 ATOM 3298 C CA . VAL C 3 10 ? 5.512 1.747 17.859 1.00 29.66 ? 10 VAL C CA 1 ATOM 3299 C C . VAL C 3 10 ? 6.812 2.416 17.420 1.00 34.33 ? 10 VAL C C 1 ATOM 3300 O O . VAL C 3 10 ? 7.039 2.601 16.219 1.00 27.46 ? 10 VAL C O 1 ATOM 3301 C CB . VAL C 3 10 ? 4.679 2.690 18.772 1.00 31.40 ? 10 VAL C CB 1 ATOM 3302 C CG1 . VAL C 3 10 ? 4.461 4.039 18.109 1.00 30.01 ? 10 VAL C CG1 1 ATOM 3303 C CG2 . VAL C 3 10 ? 3.321 2.079 19.102 1.00 33.57 ? 10 VAL C CG2 1 ATOM 3304 N N . TRP C 3 11 ? 7.657 2.749 18.394 1.00 29.26 ? 11 TRP C N 1 ATOM 3305 C CA . TRP C 3 11 ? 8.882 3.507 18.163 1.00 33.45 ? 11 TRP C CA 1 ATOM 3306 C C . TRP C 3 11 ? 9.733 3.431 19.399 1.00 48.23 ? 11 TRP C C 1 ATOM 3307 O O . TRP C 3 11 ? 9.219 3.219 20.511 1.00 42.82 ? 11 TRP C O 1 ATOM 3308 C CB . TRP C 3 11 ? 8.511 4.956 17.899 1.00 28.19 ? 11 TRP C CB 1 ATOM 3309 C CG . TRP C 3 11 ? 9.471 5.772 17.077 1.00 28.26 ? 11 TRP C CG 1 ATOM 3310 C CD1 . TRP C 3 11 ? 10.417 6.696 17.536 1.00 26.86 ? 11 TRP C CD1 1 ATOM 3311 C CD2 . TRP C 3 11 ? 9.566 5.820 15.605 1.00 23.06 ? 11 TRP C CD2 1 ATOM 3312 N NE1 . TRP C 3 11 ? 11.083 7.270 16.482 1.00 25.14 ? 11 TRP C NE1 1 ATOM 3313 C CE2 . TRP C 3 11 ? 10.619 6.790 15.295 1.00 24.41 ? 11 TRP C CE2 1 ATOM 3314 C CE3 . TRP C 3 11 ? 8.917 5.166 14.559 1.00 25.52 ? 11 TRP C CE3 1 ATOM 3315 C CZ2 . TRP C 3 11 ? 10.981 7.095 13.977 1.00 24.04 ? 11 TRP C CZ2 1 ATOM 3316 C CZ3 . TRP C 3 11 ? 9.296 5.467 13.238 1.00 23.50 ? 11 TRP C CZ3 1 ATOM 3317 C CH2 . TRP C 3 11 ? 10.302 6.415 12.958 1.00 24.69 ? 11 TRP C CH2 1 ATOM 3318 N N . CYS C 3 12 ? 11.042 3.609 19.229 1.00 46.96 ? 12 CYS C N 1 ATOM 3319 C CA . CYS C 3 12 ? 11.964 3.623 20.360 1.00 40.65 ? 12 CYS C CA 1 ATOM 3320 C C . CYS C 3 12 ? 12.908 4.809 20.270 1.00 41.01 ? 12 CYS C C 1 ATOM 3321 O O . CYS C 3 12 ? 13.325 5.186 19.176 1.00 34.97 ? 12 CYS C O 1 ATOM 3322 C CB . CYS C 3 12 ? 12.792 2.337 20.389 1.00 44.38 ? 12 CYS C CB 1 ATOM 3323 S SG . CYS C 3 12 ? 11.859 0.801 20.579 1.00 44.12 ? 12 CYS C SG 1 ATOM 3324 N N . THR C 3 13 ? 13.245 5.403 21.415 1.00 43.97 ? 13 THR C N 1 ATOM 3325 C CA . THR C 3 13 ? 14.358 6.352 21.462 1.00 59.40 ? 13 THR C CA 1 ATOM 3326 C C . THR C 3 13 ? 15.323 6.014 22.596 1.00 81.27 ? 13 THR C C 1 ATOM 3327 O O . THR C 3 13 ? 14.927 5.909 23.758 1.00 88.53 ? 13 THR C O 1 ATOM 3328 C CB . THR C 3 13 ? 13.918 7.836 21.539 1.00 62.88 ? 13 THR C CB 1 ATOM 3329 O OG1 . THR C 3 13 ? 13.019 8.035 22.637 1.00 61.65 ? 13 THR C OG1 1 ATOM 3330 C CG2 . THR C 3 13 ? 13.262 8.284 20.229 1.00 66.30 ? 13 THR C CG2 1 ATOM 3331 O OXT . THR C 3 13 ? 16.519 5.820 22.368 1.00 93.26 ? 13 THR C OXT 1 ATOM 3332 N N . GLY D 1 17 ? -37.502 -10.887 21.282 1.00 41.58 ? 237 GLY D N 1 ATOM 3333 C CA . GLY D 1 17 ? -36.946 -9.558 20.893 1.00 40.23 ? 237 GLY D CA 1 ATOM 3334 C C . GLY D 1 17 ? -37.038 -9.277 19.395 1.00 41.84 ? 237 GLY D C 1 ATOM 3335 O O . GLY D 1 17 ? -37.974 -9.716 18.728 1.00 33.91 ? 237 GLY D O 1 ATOM 3336 N N . PRO D 1 18 ? -36.073 -8.516 18.858 1.00 36.30 ? 238 PRO D N 1 ATOM 3337 C CA . PRO D 1 18 ? -36.107 -8.140 17.449 1.00 31.19 ? 238 PRO D CA 1 ATOM 3338 C C . PRO D 1 18 ? -35.915 -9.323 16.512 1.00 32.63 ? 238 PRO D C 1 ATOM 3339 O O . PRO D 1 18 ? -35.354 -10.337 16.914 1.00 34.68 ? 238 PRO D O 1 ATOM 3340 C CB . PRO D 1 18 ? -34.927 -7.165 17.313 1.00 30.37 ? 238 PRO D CB 1 ATOM 3341 C CG . PRO D 1 18 ? -34.086 -7.388 18.522 1.00 34.62 ? 238 PRO D CG 1 ATOM 3342 C CD . PRO D 1 18 ? -35.051 -7.758 19.598 1.00 34.65 ? 238 PRO D CD 1 ATOM 3343 N N . SER D 1 19 ? -36.381 -9.178 15.275 1.00 34.84 ? 239 SER D N 1 ATOM 3344 C CA . SER D 1 19 ? -36.139 -10.169 14.211 1.00 38.13 ? 239 SER D CA 1 ATOM 3345 C C . SER D 1 19 ? -35.365 -9.505 13.077 1.00 37.68 ? 239 SER D C 1 ATOM 3346 O O . SER D 1 19 ? -35.467 -8.290 12.868 1.00 31.23 ? 239 SER D O 1 ATOM 3347 C CB . SER D 1 19 ? -37.455 -10.743 13.677 1.00 35.69 ? 239 SER D CB 1 ATOM 3348 O OG . SER D 1 19 ? -38.268 -11.213 14.737 1.00 50.78 ? 239 SER D OG 1 ATOM 3349 N N . VAL D 1 20 ? -34.601 -10.305 12.341 1.00 34.10 ? 240 VAL D N 1 ATOM 3350 C CA . VAL D 1 20 ? -33.665 -9.771 11.373 1.00 29.19 ? 240 VAL D CA 1 ATOM 3351 C C . VAL D 1 20 ? -33.974 -10.327 9.981 1.00 34.30 ? 240 VAL D C 1 ATOM 3352 O O . VAL D 1 20 ? -34.183 -11.531 9.804 1.00 31.10 ? 240 VAL D O 1 ATOM 3353 C CB . VAL D 1 20 ? -32.203 -10.076 11.790 1.00 30.52 ? 240 VAL D CB 1 ATOM 3354 C CG1 . VAL D 1 20 ? -31.201 -9.475 10.812 1.00 26.55 ? 240 VAL D CG1 1 ATOM 3355 C CG2 . VAL D 1 20 ? -31.925 -9.574 13.208 1.00 26.37 ? 240 VAL D CG2 1 ATOM 3356 N N . PHE D 1 21 ? -34.009 -9.435 9.001 1.00 31.84 ? 241 PHE D N 1 ATOM 3357 C CA . PHE D 1 21 ? -34.212 -9.830 7.614 1.00 32.53 ? 241 PHE D CA 1 ATOM 3358 C C . PHE D 1 21 ? -33.121 -9.205 6.757 1.00 31.16 ? 241 PHE D C 1 ATOM 3359 O O . PHE D 1 21 ? -32.947 -7.986 6.734 1.00 32.69 ? 241 PHE D O 1 ATOM 3360 C CB . PHE D 1 21 ? -35.613 -9.438 7.154 1.00 32.69 ? 241 PHE D CB 1 ATOM 3361 C CG . PHE D 1 21 ? -36.702 -10.048 7.986 1.00 34.72 ? 241 PHE D CG 1 ATOM 3362 C CD1 . PHE D 1 21 ? -37.061 -11.381 7.816 1.00 37.07 ? 241 PHE D CD1 1 ATOM 3363 C CD2 . PHE D 1 21 ? -37.343 -9.303 8.966 1.00 41.35 ? 241 PHE D CD2 1 ATOM 3364 C CE1 . PHE D 1 21 ? -38.049 -11.958 8.600 1.00 38.71 ? 241 PHE D CE1 1 ATOM 3365 C CE2 . PHE D 1 21 ? -38.338 -9.871 9.747 1.00 44.55 ? 241 PHE D CE2 1 ATOM 3366 C CZ . PHE D 1 21 ? -38.691 -11.197 9.564 1.00 42.02 ? 241 PHE D CZ 1 ATOM 3367 N N . LEU D 1 22 ? -32.357 -10.060 6.090 1.00 32.44 ? 242 LEU D N 1 ATOM 3368 C CA . LEU D 1 22 ? -31.217 -9.614 5.321 1.00 32.00 ? 242 LEU D CA 1 ATOM 3369 C C . LEU D 1 22 ? -31.527 -9.750 3.834 1.00 33.28 ? 242 LEU D C 1 ATOM 3370 O O . LEU D 1 22 ? -31.863 -10.832 3.361 1.00 34.66 ? 242 LEU D O 1 ATOM 3371 C CB . LEU D 1 22 ? -29.970 -10.404 5.734 1.00 32.06 ? 242 LEU D CB 1 ATOM 3372 C CG . LEU D 1 22 ? -28.628 -10.117 5.050 1.00 26.30 ? 242 LEU D CG 1 ATOM 3373 C CD1 . LEU D 1 22 ? -28.190 -8.679 5.235 1.00 20.73 ? 242 LEU D CD1 1 ATOM 3374 C CD2 . LEU D 1 22 ? -27.560 -11.087 5.522 1.00 24.09 ? 242 LEU D CD2 1 ATOM 3375 N N . PHE D 1 23 ? -31.415 -8.641 3.108 1.00 30.53 ? 243 PHE D N 1 ATOM 3376 C CA . PHE D 1 23 ? -31.892 -8.562 1.725 1.00 34.21 ? 243 PHE D CA 1 ATOM 3377 C C . PHE D 1 23 ? -30.765 -8.385 0.710 1.00 34.00 ? 243 PHE D C 1 ATOM 3378 O O . PHE D 1 23 ? -29.852 -7.594 0.925 1.00 33.08 ? 243 PHE D O 1 ATOM 3379 C CB . PHE D 1 23 ? -32.922 -7.429 1.582 1.00 32.48 ? 243 PHE D CB 1 ATOM 3380 C CG . PHE D 1 23 ? -34.168 -7.637 2.400 1.00 35.96 ? 243 PHE D CG 1 ATOM 3381 C CD1 . PHE D 1 23 ? -35.245 -8.353 1.883 1.00 42.34 ? 243 PHE D CD1 1 ATOM 3382 C CD2 . PHE D 1 23 ? -34.262 -7.130 3.695 1.00 41.25 ? 243 PHE D CD2 1 ATOM 3383 C CE1 . PHE D 1 23 ? -36.395 -8.551 2.634 1.00 40.94 ? 243 PHE D CE1 1 ATOM 3384 C CE2 . PHE D 1 23 ? -35.410 -7.325 4.451 1.00 44.38 ? 243 PHE D CE2 1 ATOM 3385 C CZ . PHE D 1 23 ? -36.478 -8.040 3.918 1.00 44.05 ? 243 PHE D CZ 1 ATOM 3386 N N . PRO D 1 24 ? -30.834 -9.118 -0.409 1.00 34.56 ? 244 PRO D N 1 ATOM 3387 C CA . PRO D 1 24 ? -29.801 -9.036 -1.449 1.00 35.26 ? 244 PRO D CA 1 ATOM 3388 C C . PRO D 1 24 ? -29.853 -7.697 -2.200 1.00 24.70 ? 244 PRO D C 1 ATOM 3389 O O . PRO D 1 24 ? -30.765 -6.918 -1.983 1.00 25.77 ? 244 PRO D O 1 ATOM 3390 C CB . PRO D 1 24 ? -30.161 -10.209 -2.378 1.00 34.50 ? 244 PRO D CB 1 ATOM 3391 C CG . PRO D 1 24 ? -31.640 -10.349 -2.235 1.00 29.11 ? 244 PRO D CG 1 ATOM 3392 C CD . PRO D 1 24 ? -31.932 -10.030 -0.792 1.00 36.01 ? 244 PRO D CD 1 ATOM 3393 N N . PRO D 1 25 ? -28.872 -7.417 -3.073 1.00 27.43 ? 245 PRO D N 1 ATOM 3394 C CA . PRO D 1 25 ? -29.072 -6.224 -3.903 1.00 26.45 ? 245 PRO D CA 1 ATOM 3395 C C . PRO D 1 25 ? -30.057 -6.514 -5.019 1.00 30.73 ? 245 PRO D C 1 ATOM 3396 O O . PRO D 1 25 ? -30.391 -7.673 -5.261 1.00 31.11 ? 245 PRO D O 1 ATOM 3397 C CB . PRO D 1 25 ? -27.676 -5.927 -4.469 1.00 23.44 ? 245 PRO D CB 1 ATOM 3398 C CG . PRO D 1 25 ? -26.851 -7.149 -4.228 1.00 26.23 ? 245 PRO D CG 1 ATOM 3399 C CD . PRO D 1 25 ? -27.620 -8.128 -3.384 1.00 25.99 ? 245 PRO D CD 1 ATOM 3400 N N . LYS D 1 26 ? -30.529 -5.470 -5.685 1.00 34.18 ? 246 LYS D N 1 ATOM 3401 C CA . LYS D 1 26 ? -31.377 -5.646 -6.857 1.00 35.68 ? 246 LYS D CA 1 ATOM 3402 C C . LYS D 1 26 ? -30.527 -6.183 -7.990 1.00 35.20 ? 246 LYS D C 1 ATOM 3403 O O . LYS D 1 26 ? -29.394 -5.739 -8.177 1.00 33.70 ? 246 LYS D O 1 ATOM 3404 C CB . LYS D 1 26 ? -32.013 -4.319 -7.282 1.00 41.08 ? 246 LYS D CB 1 ATOM 3405 C CG . LYS D 1 26 ? -33.014 -3.752 -6.293 1.00 51.48 ? 246 LYS D CG 1 ATOM 3406 C CD . LYS D 1 26 ? -34.244 -4.645 -6.141 1.00 56.98 ? 246 LYS D CD 1 ATOM 3407 C CE . LYS D 1 26 ? -35.096 -4.206 -4.961 1.00 58.84 ? 246 LYS D CE 1 ATOM 3408 N NZ . LYS D 1 26 ? -34.386 -4.367 -3.657 1.00 50.11 ? 246 LYS D NZ 1 ATOM 3409 N N . PRO D 1 27 ? -31.055 -7.166 -8.735 1.00 38.99 ? 247 PRO D N 1 ATOM 3410 C CA . PRO D 1 27 ? -30.318 -7.723 -9.858 1.00 41.12 ? 247 PRO D CA 1 ATOM 3411 C C . PRO D 1 27 ? -29.729 -6.665 -10.789 1.00 36.29 ? 247 PRO D C 1 ATOM 3412 O O . PRO D 1 27 ? -28.612 -6.838 -11.280 1.00 43.57 ? 247 PRO D O 1 ATOM 3413 C CB . PRO D 1 27 ? -31.381 -8.551 -10.575 1.00 42.92 ? 247 PRO D CB 1 ATOM 3414 C CG . PRO D 1 27 ? -32.222 -9.068 -9.449 1.00 37.23 ? 247 PRO D CG 1 ATOM 3415 C CD . PRO D 1 27 ? -32.299 -7.918 -8.480 1.00 38.60 ? 247 PRO D CD 1 ATOM 3416 N N . LYS D 1 28 ? -30.456 -5.576 -11.011 1.00 32.14 ? 248 LYS D N 1 ATOM 3417 C CA . LYS D 1 28 ? -30.022 -4.555 -11.967 1.00 37.54 ? 248 LYS D CA 1 ATOM 3418 C C . LYS D 1 28 ? -28.773 -3.857 -11.459 1.00 35.41 ? 248 LYS D C 1 ATOM 3419 O O . LYS D 1 28 ? -27.922 -3.450 -12.242 1.00 34.34 ? 248 LYS D O 1 ATOM 3420 C CB . LYS D 1 28 ? -31.132 -3.530 -12.218 1.00 39.30 ? 248 LYS D CB 1 ATOM 3421 C CG . LYS D 1 28 ? -31.189 -3.039 -13.652 1.00 43.65 ? 248 LYS D CG 1 ATOM 3422 C CD . LYS D 1 28 ? -32.549 -2.448 -13.996 1.00 42.88 ? 248 LYS D CD 1 ATOM 3423 C CE . LYS D 1 28 ? -32.457 -0.977 -14.367 1.00 39.67 ? 248 LYS D CE 1 ATOM 3424 N NZ . LYS D 1 28 ? -33.763 -0.486 -14.898 1.00 38.42 ? 248 LYS D NZ 1 ATOM 3425 N N . ASP D 1 29 ? -28.670 -3.743 -10.139 1.00 34.82 ? 249 ASP D N 1 ATOM 3426 C CA . ASP D 1 29 ? -27.570 -3.052 -9.493 1.00 31.14 ? 249 ASP D CA 1 ATOM 3427 C C . ASP D 1 29 ? -26.272 -3.852 -9.499 1.00 32.15 ? 249 ASP D C 1 ATOM 3428 O O . ASP D 1 29 ? -25.191 -3.270 -9.418 1.00 39.48 ? 249 ASP D O 1 ATOM 3429 C CB . ASP D 1 29 ? -27.950 -2.702 -8.055 1.00 35.14 ? 249 ASP D CB 1 ATOM 3430 C CG . ASP D 1 29 ? -29.020 -1.628 -7.969 1.00 45.99 ? 249 ASP D CG 1 ATOM 3431 O OD1 . ASP D 1 29 ? -29.278 -0.934 -8.979 1.00 45.06 ? 249 ASP D OD1 1 ATOM 3432 O OD2 . ASP D 1 29 ? -29.609 -1.479 -6.875 1.00 43.64 ? 249 ASP D OD2 1 ATOM 3433 N N . THR D 1 30 ? -26.375 -5.178 -9.566 1.00 27.50 ? 250 THR D N 1 ATOM 3434 C CA . THR D 1 30 ? -25.189 -6.028 -9.599 1.00 30.99 ? 250 THR D CA 1 ATOM 3435 C C . THR D 1 30 ? -24.686 -6.210 -11.033 1.00 35.18 ? 250 THR D C 1 ATOM 3436 O O . THR D 1 30 ? -23.517 -6.560 -11.248 1.00 32.27 ? 250 THR D O 1 ATOM 3437 C CB . THR D 1 30 ? -25.430 -7.426 -8.969 1.00 32.79 ? 250 THR D CB 1 ATOM 3438 O OG1 . THR D 1 30 ? -26.315 -8.191 -9.796 1.00 30.57 ? 250 THR D OG1 1 ATOM 3439 C CG2 . THR D 1 30 ? -26.014 -7.320 -7.563 1.00 32.91 ? 250 THR D CG2 1 ATOM 3440 N N . LEU D 1 31 ? -25.573 -5.971 -12.001 1.00 31.34 ? 251 LEU D N 1 ATOM 3441 C CA . LEU D 1 31 ? -25.274 -6.198 -13.422 1.00 32.71 ? 251 LEU D CA 1 ATOM 3442 C C . LEU D 1 31 ? -24.884 -4.947 -14.186 1.00 27.80 ? 251 LEU D C 1 ATOM 3443 O O . LEU D 1 31 ? -24.327 -5.031 -15.274 1.00 37.73 ? 251 LEU D O 1 ATOM 3444 C CB . LEU D 1 31 ? -26.457 -6.882 -14.119 1.00 29.18 ? 251 LEU D CB 1 ATOM 3445 C CG . LEU D 1 31 ? -26.921 -8.212 -13.511 1.00 32.12 ? 251 LEU D CG 1 ATOM 3446 C CD1 . LEU D 1 31 ? -28.159 -8.722 -14.232 1.00 34.93 ? 251 LEU D CD1 1 ATOM 3447 C CD2 . LEU D 1 31 ? -25.812 -9.259 -13.530 1.00 33.84 ? 251 LEU D CD2 1 ATOM 3448 N N . MET D 1 32 ? -25.206 -3.789 -13.636 1.00 31.10 ? 252 MET D N 1 ATOM 3449 C CA . MET D 1 32 ? -24.851 -2.538 -14.263 1.00 30.37 ? 252 MET D CA 1 ATOM 3450 C C . MET D 1 32 ? -23.715 -1.926 -13.476 1.00 37.10 ? 252 MET D C 1 ATOM 3451 O O . MET D 1 32 ? -23.835 -1.713 -12.261 1.00 32.54 ? 252 MET D O 1 ATOM 3452 C CB . MET D 1 32 ? -26.052 -1.590 -14.307 1.00 33.46 ? 252 MET D CB 1 ATOM 3453 C CG . MET D 1 32 ? -27.187 -2.047 -15.217 1.00 36.81 ? 252 MET D CG 1 ATOM 3454 S SD . MET D 1 32 ? -28.602 -0.916 -15.246 1.00 39.28 ? 252 MET D SD 1 ATOM 3455 C CE . MET D 1 32 ? -27.908 0.501 -16.096 1.00 38.48 ? 252 MET D CE 1 ATOM 3456 N N . ILE D 1 33 ? -22.605 -1.661 -14.162 1.00 38.16 ? 253 ILE D N 1 ATOM 3457 C CA . ILE D 1 33 ? -21.421 -1.079 -13.520 1.00 43.63 ? 253 ILE D CA 1 ATOM 3458 C C . ILE D 1 33 ? -21.687 0.359 -13.044 1.00 41.44 ? 253 ILE D C 1 ATOM 3459 O O . ILE D 1 33 ? -21.029 0.851 -12.129 1.00 41.86 ? 253 ILE D O 1 ATOM 3460 C CB . ILE D 1 33 ? -20.176 -1.153 -14.449 1.00 45.59 ? 253 ILE D CB 1 ATOM 3461 C CG1 . ILE D 1 33 ? -18.859 -1.079 -13.652 1.00 46.15 ? 253 ILE D CG1 1 ATOM 3462 C CG2 . ILE D 1 33 ? -20.220 -0.065 -15.518 1.00 43.46 ? 253 ILE D CG2 1 ATOM 3463 C CD1 . ILE D 1 33 ? -18.496 -2.322 -12.862 1.00 43.92 ? 253 ILE D CD1 1 ATOM 3464 N N . SER D 1 34 ? -22.667 1.015 -13.659 1.00 44.02 ? 254 SER D N 1 ATOM 3465 C CA . SER D 1 34 ? -23.010 2.401 -13.325 1.00 39.19 ? 254 SER D CA 1 ATOM 3466 C C . SER D 1 34 ? -23.897 2.513 -12.091 1.00 34.97 ? 254 SER D C 1 ATOM 3467 O O . SER D 1 34 ? -24.092 3.607 -11.568 1.00 40.06 ? 254 SER D O 1 ATOM 3468 C CB . SER D 1 34 ? -23.674 3.094 -14.514 1.00 37.20 ? 254 SER D CB 1 ATOM 3469 O OG . SER D 1 34 ? -24.682 2.273 -15.075 1.00 44.32 ? 254 SER D OG 1 ATOM 3470 N N . ARG D 1 35 ? -24.424 1.383 -11.626 1.00 33.93 ? 255 ARG D N 1 ATOM 3471 C CA . ARG D 1 35 ? -25.205 1.347 -10.383 1.00 37.59 ? 255 ARG D CA 1 ATOM 3472 C C . ARG D 1 35 ? -24.409 0.872 -9.176 1.00 38.89 ? 255 ARG D C 1 ATOM 3473 O O . ARG D 1 35 ? -23.325 0.311 -9.314 1.00 47.88 ? 255 ARG D O 1 ATOM 3474 C CB . ARG D 1 35 ? -26.452 0.489 -10.560 1.00 36.73 ? 255 ARG D CB 1 ATOM 3475 C CG . ARG D 1 35 ? -27.490 1.162 -11.435 1.00 43.39 ? 255 ARG D CG 1 ATOM 3476 C CD . ARG D 1 35 ? -28.647 0.237 -11.744 1.00 50.58 ? 255 ARG D CD 1 ATOM 3477 N NE . ARG D 1 35 ? -29.466 0.798 -12.808 1.00 59.09 ? 255 ARG D NE 1 ATOM 3478 C CZ . ARG D 1 35 ? -30.395 1.734 -12.639 1.00 50.91 ? 255 ARG D CZ 1 ATOM 3479 N NH1 . ARG D 1 35 ? -30.649 2.234 -11.432 1.00 50.65 ? 255 ARG D NH1 1 ATOM 3480 N NH2 . ARG D 1 35 ? -31.068 2.171 -13.690 1.00 40.99 ? 255 ARG D NH2 1 ATOM 3481 N N . THR D 1 36 ? -24.965 1.087 -7.992 1.00 36.82 ? 256 THR D N 1 ATOM 3482 C CA . THR D 1 36 ? -24.312 0.695 -6.754 1.00 42.93 ? 256 THR D CA 1 ATOM 3483 C C . THR D 1 36 ? -25.145 -0.346 -6.018 1.00 39.67 ? 256 THR D C 1 ATOM 3484 O O . THR D 1 36 ? -26.170 -0.016 -5.437 1.00 39.44 ? 256 THR D O 1 ATOM 3485 C CB . THR D 1 36 ? -24.062 1.909 -5.859 1.00 43.90 ? 256 THR D CB 1 ATOM 3486 O OG1 . THR D 1 36 ? -23.285 2.859 -6.594 1.00 59.20 ? 256 THR D OG1 1 ATOM 3487 C CG2 . THR D 1 36 ? -23.308 1.510 -4.596 1.00 48.31 ? 256 THR D CG2 1 ATOM 3488 N N . PRO D 1 37 ? -24.712 -1.616 -6.063 1.00 38.78 ? 257 PRO D N 1 ATOM 3489 C CA . PRO D 1 37 ? -25.459 -2.677 -5.407 1.00 34.96 ? 257 PRO D CA 1 ATOM 3490 C C . PRO D 1 37 ? -25.151 -2.715 -3.911 1.00 35.49 ? 257 PRO D C 1 ATOM 3491 O O . PRO D 1 37 ? -24.017 -2.454 -3.498 1.00 34.17 ? 257 PRO D O 1 ATOM 3492 C CB . PRO D 1 37 ? -24.956 -3.935 -6.105 1.00 36.81 ? 257 PRO D CB 1 ATOM 3493 C CG . PRO D 1 37 ? -23.565 -3.605 -6.525 1.00 39.36 ? 257 PRO D CG 1 ATOM 3494 C CD . PRO D 1 37 ? -23.540 -2.129 -6.800 1.00 40.14 ? 257 PRO D CD 1 ATOM 3495 N N . GLU D 1 38 ? -26.167 -3.010 -3.113 1.00 30.84 ? 258 GLU D N 1 ATOM 3496 C CA . GLU D 1 38 ? -26.014 -3.065 -1.658 1.00 41.89 ? 258 GLU D CA 1 ATOM 3497 C C . GLU D 1 38 ? -26.793 -4.236 -1.050 1.00 42.78 ? 258 GLU D C 1 ATOM 3498 O O . GLU D 1 38 ? -27.791 -4.705 -1.615 1.00 36.88 ? 258 GLU D O 1 ATOM 3499 C CB . GLU D 1 38 ? -26.434 -1.735 -1.022 1.00 38.55 ? 258 GLU D CB 1 ATOM 3500 C CG . GLU D 1 38 ? -27.707 -1.147 -1.618 1.00 48.56 ? 258 GLU D CG 1 ATOM 3501 C CD . GLU D 1 38 ? -28.065 0.233 -1.093 1.00 49.46 ? 258 GLU D CD 1 ATOM 3502 O OE1 . GLU D 1 38 ? -29.220 0.397 -0.649 1.00 56.92 ? 258 GLU D OE1 1 ATOM 3503 O OE2 . GLU D 1 38 ? -27.215 1.154 -1.130 1.00 46.12 ? 258 GLU D OE2 1 ATOM 3504 N N . VAL D 1 39 ? -26.297 -4.731 0.080 1.00 37.33 ? 259 VAL D N 1 ATOM 3505 C CA . VAL D 1 39 ? -27.017 -5.721 0.873 1.00 34.50 ? 259 VAL D CA 1 ATOM 3506 C C . VAL D 1 39 ? -27.603 -5.000 2.076 1.00 36.49 ? 259 VAL D C 1 ATOM 3507 O O . VAL D 1 39 ? -26.949 -4.119 2.651 1.00 33.21 ? 259 VAL D O 1 ATOM 3508 C CB . VAL D 1 39 ? -26.134 -6.915 1.300 1.00 30.48 ? 259 VAL D CB 1 ATOM 3509 C CG1 . VAL D 1 39 ? -25.786 -7.763 0.097 1.00 31.76 ? 259 VAL D CG1 1 ATOM 3510 C CG2 . VAL D 1 39 ? -24.868 -6.454 2.002 1.00 33.73 ? 259 VAL D CG2 1 ATOM 3511 N N . THR D 1 40 ? -28.840 -5.356 2.430 1.00 33.84 ? 260 THR D N 1 ATOM 3512 C CA . THR D 1 40 ? -29.602 -4.618 3.427 1.00 31.67 ? 260 THR D CA 1 ATOM 3513 C C . THR D 1 40 ? -30.001 -5.490 4.622 1.00 31.02 ? 260 THR D C 1 ATOM 3514 O O . THR D 1 40 ? -30.644 -6.527 4.453 1.00 26.11 ? 260 THR D O 1 ATOM 3515 C CB . THR D 1 40 ? -30.831 -3.926 2.789 1.00 28.38 ? 260 THR D CB 1 ATOM 3516 O OG1 . THR D 1 40 ? -30.381 -3.025 1.773 1.00 29.86 ? 260 THR D OG1 1 ATOM 3517 C CG2 . THR D 1 40 ? -31.577 -3.110 3.812 1.00 30.46 ? 260 THR D CG2 1 ATOM 3518 N N . CYS D 1 41 ? -29.615 -5.055 5.824 1.00 28.81 ? 261 CYS D N 1 ATOM 3519 C CA . CYS D 1 41 ? -29.942 -5.783 7.059 1.00 27.61 ? 261 CYS D CA 1 ATOM 3520 C C . CYS D 1 41 ? -30.967 -4.991 7.858 1.00 26.10 ? 261 CYS D C 1 ATOM 3521 O O . CYS D 1 41 ? -30.657 -3.934 8.411 1.00 22.33 ? 261 CYS D O 1 ATOM 3522 C CB . CYS D 1 41 ? -28.680 -6.011 7.894 1.00 34.64 ? 261 CYS D CB 1 ATOM 3523 S SG . CYS D 1 41 ? -28.807 -7.163 9.293 1.00 31.93 ? 261 CYS D SG 1 ATOM 3524 N N . VAL D 1 42 ? -32.191 -5.513 7.899 1.00 29.17 ? 262 VAL D N 1 ATOM 3525 C CA . VAL D 1 42 ? -33.336 -4.844 8.516 1.00 23.34 ? 262 VAL D CA 1 ATOM 3526 C C . VAL D 1 42 ? -33.614 -5.498 9.863 1.00 24.64 ? 262 VAL D C 1 ATOM 3527 O O . VAL D 1 42 ? -33.722 -6.718 9.969 1.00 25.75 ? 262 VAL D O 1 ATOM 3528 C CB . VAL D 1 42 ? -34.573 -4.916 7.582 1.00 26.46 ? 262 VAL D CB 1 ATOM 3529 C CG1 . VAL D 1 42 ? -35.823 -4.330 8.231 1.00 21.78 ? 262 VAL D CG1 1 ATOM 3530 C CG2 . VAL D 1 42 ? -34.279 -4.181 6.278 1.00 26.36 ? 262 VAL D CG2 1 ATOM 3531 N N . VAL D 1 43 ? -33.673 -4.678 10.899 1.00 26.52 ? 263 VAL D N 1 ATOM 3532 C CA . VAL D 1 43 ? -34.001 -5.153 12.237 1.00 21.83 ? 263 VAL D CA 1 ATOM 3533 C C . VAL D 1 43 ? -35.369 -4.565 12.600 1.00 23.07 ? 263 VAL D C 1 ATOM 3534 O O . VAL D 1 43 ? -35.519 -3.343 12.677 1.00 22.56 ? 263 VAL D O 1 ATOM 3535 C CB . VAL D 1 43 ? -32.965 -4.703 13.275 1.00 21.10 ? 263 VAL D CB 1 ATOM 3536 C CG1 . VAL D 1 43 ? -33.227 -5.397 14.609 1.00 23.73 ? 263 VAL D CG1 1 ATOM 3537 C CG2 . VAL D 1 43 ? -31.545 -5.027 12.826 1.00 21.51 ? 263 VAL D CG2 1 ATOM 3538 N N . VAL D 1 44 ? -36.372 -5.429 12.781 1.00 24.31 ? 264 VAL D N 1 ATOM 3539 C CA . VAL D 1 44 ? -37.715 -4.976 13.183 1.00 29.32 ? 264 VAL D CA 1 ATOM 3540 C C . VAL D 1 44 ? -37.985 -5.422 14.620 1.00 27.22 ? 264 VAL D C 1 ATOM 3541 O O . VAL D 1 44 ? -37.227 -6.198 15.161 1.00 30.41 ? 264 VAL D O 1 ATOM 3542 C CB . VAL D 1 44 ? -38.822 -5.514 12.247 1.00 29.56 ? 264 VAL D CB 1 ATOM 3543 C CG1 . VAL D 1 44 ? -38.713 -4.877 10.869 1.00 30.22 ? 264 VAL D CG1 1 ATOM 3544 C CG2 . VAL D 1 44 ? -38.772 -7.035 12.144 1.00 32.08 ? 264 VAL D CG2 1 ATOM 3545 N N . ASP D 1 45 ? -39.054 -4.931 15.231 1.00 25.59 ? 265 ASP D N 1 ATOM 3546 C CA . ASP D 1 45 ? -39.412 -5.327 16.589 1.00 26.43 ? 265 ASP D CA 1 ATOM 3547 C C . ASP D 1 45 ? -38.367 -4.904 17.618 1.00 29.06 ? 265 ASP D C 1 ATOM 3548 O O . ASP D 1 45 ? -38.228 -5.524 18.660 1.00 27.79 ? 265 ASP D O 1 ATOM 3549 C CB . ASP D 1 45 ? -39.694 -6.836 16.673 1.00 27.16 ? 265 ASP D CB 1 ATOM 3550 C CG . ASP D 1 45 ? -41.073 -7.198 16.168 1.00 29.56 ? 265 ASP D CG 1 ATOM 3551 O OD1 . ASP D 1 45 ? -41.901 -6.288 15.991 1.00 35.71 ? 265 ASP D OD1 1 ATOM 3552 O OD2 . ASP D 1 45 ? -41.331 -8.393 15.945 1.00 36.05 ? 265 ASP D OD2 1 ATOM 3553 N N . VAL D 1 46 ? -37.646 -3.835 17.298 1.00 34.43 ? 266 VAL D N 1 ATOM 3554 C CA . VAL D 1 46 ? -36.699 -3.200 18.200 1.00 36.20 ? 266 VAL D CA 1 ATOM 3555 C C . VAL D 1 46 ? -37.519 -2.379 19.179 1.00 37.63 ? 266 VAL D C 1 ATOM 3556 O O . VAL D 1 46 ? -38.337 -1.558 18.766 1.00 42.06 ? 266 VAL D O 1 ATOM 3557 C CB . VAL D 1 46 ? -35.712 -2.289 17.418 1.00 31.65 ? 266 VAL D CB 1 ATOM 3558 C CG1 . VAL D 1 46 ? -34.941 -1.368 18.342 1.00 27.13 ? 266 VAL D CG1 1 ATOM 3559 C CG2 . VAL D 1 46 ? -34.763 -3.118 16.577 1.00 28.52 ? 266 VAL D CG2 1 ATOM 3560 N N . SER D 1 47 ? -37.289 -2.595 20.472 1.00 42.33 ? 267 SER D N 1 ATOM 3561 C CA . SER D 1 47 ? -38.125 -2.001 21.510 1.00 37.99 ? 267 SER D CA 1 ATOM 3562 C C . SER D 1 47 ? -37.784 -0.546 21.777 1.00 37.39 ? 267 SER D C 1 ATOM 3563 O O . SER D 1 47 ? -36.681 -0.090 21.471 1.00 41.82 ? 267 SER D O 1 ATOM 3564 C CB . SER D 1 47 ? -38.009 -2.803 22.802 1.00 37.32 ? 267 SER D CB 1 ATOM 3565 O OG . SER D 1 47 ? -36.684 -2.759 23.290 1.00 45.40 ? 267 SER D OG 1 ATOM 3566 N N . HIS D 1 48 ? -38.742 0.171 22.360 1.00 32.70 ? 268 HIS D N 1 ATOM 3567 C CA . HIS D 1 48 ? -38.541 1.549 22.782 1.00 42.35 ? 268 HIS D CA 1 ATOM 3568 C C . HIS D 1 48 ? -37.558 1.660 23.905 1.00 42.60 ? 268 HIS D C 1 ATOM 3569 O O . HIS D 1 48 ? -36.833 2.655 23.994 1.00 39.69 ? 268 HIS D O 1 ATOM 3570 C CB . HIS D 1 48 ? -39.866 2.190 23.181 1.00 40.67 ? 268 HIS D CB 1 ATOM 3571 C CG . HIS D 1 48 ? -40.460 3.051 22.105 1.00 44.12 ? 268 HIS D CG 1 ATOM 3572 N ND1 . HIS D 1 48 ? -40.774 2.571 20.886 1.00 49.51 ? 268 HIS D ND1 1 ATOM 3573 C CD2 . HIS D 1 48 ? -40.785 4.400 22.093 1.00 47.38 ? 268 HIS D CD2 1 ATOM 3574 C CE1 . HIS D 1 48 ? -41.273 3.558 20.132 1.00 45.43 ? 268 HIS D CE1 1 ATOM 3575 N NE2 . HIS D 1 48 ? -41.285 4.679 20.871 1.00 57.42 ? 268 HIS D NE2 1 ATOM 3576 N N . GLU D 1 49 ? -37.530 0.627 24.753 1.00 45.90 ? 269 GLU D N 1 ATOM 3577 C CA . GLU D 1 49 ? -36.673 0.563 25.941 1.00 45.62 ? 269 GLU D CA 1 ATOM 3578 C C . GLU D 1 49 ? -35.195 0.378 25.605 1.00 46.78 ? 269 GLU D C 1 ATOM 3579 O O . GLU D 1 49 ? -34.332 0.945 26.267 1.00 44.42 ? 269 GLU D O 1 ATOM 3580 C CB . GLU D 1 49 ? -37.118 -0.576 26.861 1.00 48.05 ? 269 GLU D CB 1 ATOM 3581 C CG . GLU D 1 49 ? -38.420 -0.326 27.610 1.00 57.56 ? 269 GLU D CG 1 ATOM 3582 C CD . GLU D 1 49 ? -39.664 -0.533 26.760 1.00 53.63 ? 269 GLU D CD 1 ATOM 3583 O OE1 . GLU D 1 49 ? -39.719 -1.503 25.974 1.00 58.84 ? 269 GLU D OE1 1 ATOM 3584 O OE2 . GLU D 1 49 ? -40.596 0.283 26.886 1.00 63.12 ? 269 GLU D OE2 1 ATOM 3585 N N . ASP D 1 50 ? -34.911 -0.432 24.588 1.00 51.84 ? 270 ASP D N 1 ATOM 3586 C CA . ASP D 1 50 ? -33.534 -0.694 24.154 1.00 45.54 ? 270 ASP D CA 1 ATOM 3587 C C . ASP D 1 50 ? -33.392 -0.554 22.632 1.00 36.02 ? 270 ASP D C 1 ATOM 3588 O O . ASP D 1 50 ? -33.292 -1.558 21.919 1.00 30.01 ? 270 ASP D O 1 ATOM 3589 C CB . ASP D 1 50 ? -33.087 -2.077 24.630 1.00 40.67 ? 270 ASP D CB 1 ATOM 3590 C CG . ASP D 1 50 ? -33.002 -2.168 26.151 1.00 49.89 ? 270 ASP D CG 1 ATOM 3591 O OD1 . ASP D 1 50 ? -33.922 -2.740 26.776 1.00 54.06 ? 270 ASP D OD1 1 ATOM 3592 O OD2 . ASP D 1 50 ? -32.022 -1.651 26.724 1.00 42.79 ? 270 ASP D OD2 1 ATOM 3593 N N . PRO D 1 51 ? -33.405 0.698 22.129 1.00 36.64 ? 271 PRO D N 1 ATOM 3594 C CA . PRO D 1 51 ? -33.327 0.919 20.675 1.00 31.92 ? 271 PRO D CA 1 ATOM 3595 C C . PRO D 1 51 ? -31.940 0.657 20.085 1.00 34.84 ? 271 PRO D C 1 ATOM 3596 O O . PRO D 1 51 ? -31.799 0.536 18.870 1.00 29.60 ? 271 PRO D O 1 ATOM 3597 C CB . PRO D 1 51 ? -33.700 2.395 20.514 1.00 29.52 ? 271 PRO D CB 1 ATOM 3598 C CG . PRO D 1 51 ? -33.455 3.015 21.845 1.00 31.13 ? 271 PRO D CG 1 ATOM 3599 C CD . PRO D 1 51 ? -33.672 1.949 22.871 1.00 30.68 ? 271 PRO D CD 1 ATOM 3600 N N . GLU D 1 52 ? -30.930 0.556 20.939 1.00 29.63 ? 272 GLU D N 1 ATOM 3601 C CA . GLU D 1 52 ? -29.555 0.427 20.470 1.00 31.41 ? 272 GLU D CA 1 ATOM 3602 C C . GLU D 1 52 ? -29.301 -0.921 19.770 1.00 33.57 ? 272 GLU D C 1 ATOM 3603 O O . GLU D 1 52 ? -29.587 -1.993 20.308 1.00 31.57 ? 272 GLU D O 1 ATOM 3604 C CB . GLU D 1 52 ? -28.584 0.668 21.626 1.00 34.72 ? 272 GLU D CB 1 ATOM 3605 C CG . GLU D 1 52 ? -28.725 2.051 22.275 1.00 33.02 ? 272 GLU D CG 1 ATOM 3606 C CD . GLU D 1 52 ? -29.881 2.167 23.276 1.00 32.27 ? 272 GLU D CD 1 ATOM 3607 O OE1 . GLU D 1 52 ? -30.195 3.304 23.670 1.00 37.81 ? 272 GLU D OE1 1 ATOM 3608 O OE2 . GLU D 1 52 ? -30.486 1.147 23.678 1.00 33.35 ? 272 GLU D OE2 1 ATOM 3609 N N . VAL D 1 53 ? -28.804 -0.860 18.542 1.00 30.57 ? 273 VAL D N 1 ATOM 3610 C CA . VAL D 1 53 ? -28.491 -2.074 17.813 1.00 30.06 ? 273 VAL D CA 1 ATOM 3611 C C . VAL D 1 53 ? -27.052 -2.045 17.293 1.00 32.82 ? 273 VAL D C 1 ATOM 3612 O O . VAL D 1 53 ? -26.635 -1.065 16.668 1.00 36.59 ? 273 VAL D O 1 ATOM 3613 C CB . VAL D 1 53 ? -29.483 -2.324 16.657 1.00 26.90 ? 273 VAL D CB 1 ATOM 3614 C CG1 . VAL D 1 53 ? -29.177 -3.655 15.984 1.00 26.69 ? 273 VAL D CG1 1 ATOM 3615 C CG2 . VAL D 1 53 ? -30.917 -2.333 17.170 1.00 25.17 ? 273 VAL D CG2 1 ATOM 3616 N N . LYS D 1 54 ? -26.307 -3.121 17.553 1.00 34.54 ? 274 LYS D N 1 ATOM 3617 C CA . LYS D 1 54 ? -24.949 -3.275 17.024 1.00 35.69 ? 274 LYS D CA 1 ATOM 3618 C C . LYS D 1 54 ? -24.931 -4.202 15.820 1.00 38.26 ? 274 LYS D C 1 ATOM 3619 O O . LYS D 1 54 ? -25.397 -5.346 15.878 1.00 39.15 ? 274 LYS D O 1 ATOM 3620 C CB . LYS D 1 54 ? -23.966 -3.775 18.083 1.00 44.12 ? 274 LYS D CB 1 ATOM 3621 C CG . LYS D 1 54 ? -22.508 -3.544 17.699 1.00 57.41 ? 274 LYS D CG 1 ATOM 3622 C CD . LYS D 1 54 ? -21.537 -4.139 18.712 1.00 65.36 ? 274 LYS D CD 1 ATOM 3623 C CE . LYS D 1 54 ? -20.097 -4.102 18.208 1.00 67.35 ? 274 LYS D CE 1 ATOM 3624 N NZ . LYS D 1 54 ? -19.491 -2.737 18.190 1.00 68.82 ? 274 LYS D NZ 1 ATOM 3625 N N . PHE D 1 55 ? -24.388 -3.683 14.730 1.00 30.26 ? 275 PHE D N 1 ATOM 3626 C CA . PHE D 1 55 ? -24.236 -4.428 13.498 1.00 30.89 ? 275 PHE D CA 1 ATOM 3627 C C . PHE D 1 55 ? -22.777 -4.832 13.318 1.00 33.38 ? 275 PHE D C 1 ATOM 3628 O O . PHE D 1 55 ? -21.872 -4.004 13.460 1.00 36.96 ? 275 PHE D O 1 ATOM 3629 C CB . PHE D 1 55 ? -24.674 -3.557 12.330 1.00 24.67 ? 275 PHE D CB 1 ATOM 3630 C CG . PHE D 1 55 ? -26.144 -3.261 12.305 1.00 27.75 ? 275 PHE D CG 1 ATOM 3631 C CD1 . PHE D 1 55 ? -26.627 -2.032 12.755 1.00 26.20 ? 275 PHE D CD1 1 ATOM 3632 C CD2 . PHE D 1 55 ? -27.055 -4.210 11.821 1.00 25.05 ? 275 PHE D CD2 1 ATOM 3633 C CE1 . PHE D 1 55 ? -27.985 -1.753 12.724 1.00 26.62 ? 275 PHE D CE1 1 ATOM 3634 C CE2 . PHE D 1 55 ? -28.411 -3.935 11.790 1.00 27.73 ? 275 PHE D CE2 1 ATOM 3635 C CZ . PHE D 1 55 ? -28.880 -2.706 12.244 1.00 27.72 ? 275 PHE D CZ 1 ATOM 3636 N N . ASN D 1 56 ? -22.552 -6.114 13.051 1.00 33.75 ? 276 ASN D N 1 ATOM 3637 C CA . ASN D 1 56 ? -21.239 -6.594 12.628 1.00 34.54 ? 276 ASN D CA 1 ATOM 3638 C C . ASN D 1 56 ? -21.391 -7.228 11.262 1.00 35.73 ? 276 ASN D C 1 ATOM 3639 O O . ASN D 1 56 ? -22.220 -8.118 11.072 1.00 44.02 ? 276 ASN D O 1 ATOM 3640 C CB . ASN D 1 56 ? -20.682 -7.630 13.592 1.00 35.97 ? 276 ASN D CB 1 ATOM 3641 C CG . ASN D 1 56 ? -20.178 -7.022 14.873 1.00 33.28 ? 276 ASN D CG 1 ATOM 3642 O OD1 . ASN D 1 56 ? -20.935 -6.832 15.822 1.00 39.24 ? 276 ASN D OD1 1 ATOM 3643 N ND2 . ASN D 1 56 ? -18.891 -6.728 14.916 1.00 36.42 ? 276 ASN D ND2 1 ATOM 3644 N N . TRP D 1 57 ? -20.601 -6.756 10.312 1.00 34.66 ? 277 TRP D N 1 ATOM 3645 C CA . TRP D 1 57 ? -20.661 -7.252 8.943 1.00 31.21 ? 277 TRP D CA 1 ATOM 3646 C C . TRP D 1 57 ? -19.427 -8.032 8.593 1.00 36.66 ? 277 TRP D C 1 ATOM 3647 O O . TRP D 1 57 ? -18.316 -7.633 8.946 1.00 36.32 ? 277 TRP D O 1 ATOM 3648 C CB . TRP D 1 57 ? -20.778 -6.078 8.005 1.00 28.93 ? 277 TRP D CB 1 ATOM 3649 C CG . TRP D 1 57 ? -22.154 -5.479 7.927 1.00 32.60 ? 277 TRP D CG 1 ATOM 3650 C CD1 . TRP D 1 57 ? -22.647 -4.376 8.622 1.00 29.97 ? 277 TRP D CD1 1 ATOM 3651 C CD2 . TRP D 1 57 ? -23.255 -5.910 7.061 1.00 29.83 ? 277 TRP D CD2 1 ATOM 3652 N NE1 . TRP D 1 57 ? -23.941 -4.110 8.260 1.00 28.89 ? 277 TRP D NE1 1 ATOM 3653 C CE2 . TRP D 1 57 ? -24.368 -4.992 7.327 1.00 29.46 ? 277 TRP D CE2 1 ATOM 3654 C CE3 . TRP D 1 57 ? -23.428 -6.935 6.133 1.00 30.07 ? 277 TRP D CE3 1 ATOM 3655 C CZ2 . TRP D 1 57 ? -25.588 -5.106 6.673 1.00 27.99 ? 277 TRP D CZ2 1 ATOM 3656 C CZ3 . TRP D 1 57 ? -24.665 -7.038 5.473 1.00 30.21 ? 277 TRP D CZ3 1 ATOM 3657 C CH2 . TRP D 1 57 ? -25.714 -6.141 5.733 1.00 27.86 ? 277 TRP D CH2 1 ATOM 3658 N N . TYR D 1 58 ? -19.609 -9.148 7.888 1.00 36.61 ? 278 TYR D N 1 ATOM 3659 C CA . TYR D 1 58 ? -18.492 -9.996 7.477 1.00 35.18 ? 278 TYR D CA 1 ATOM 3660 C C . TYR D 1 58 ? -18.636 -10.367 6.011 1.00 39.92 ? 278 TYR D C 1 ATOM 3661 O O . TYR D 1 58 ? -19.739 -10.654 5.540 1.00 39.10 ? 278 TYR D O 1 ATOM 3662 C CB . TYR D 1 58 ? -18.423 -11.261 8.334 1.00 37.05 ? 278 TYR D CB 1 ATOM 3663 C CG . TYR D 1 58 ? -18.422 -10.987 9.825 1.00 38.33 ? 278 TYR D CG 1 ATOM 3664 C CD1 . TYR D 1 58 ? -19.611 -10.729 10.511 1.00 33.99 ? 278 TYR D CD1 1 ATOM 3665 C CD2 . TYR D 1 58 ? -17.234 -10.982 10.547 1.00 37.16 ? 278 TYR D CD2 1 ATOM 3666 C CE1 . TYR D 1 58 ? -19.607 -10.471 11.877 1.00 39.53 ? 278 TYR D CE1 1 ATOM 3667 C CE2 . TYR D 1 58 ? -17.223 -10.733 11.913 1.00 33.16 ? 278 TYR D CE2 1 ATOM 3668 C CZ . TYR D 1 58 ? -18.408 -10.474 12.569 1.00 36.45 ? 278 TYR D CZ 1 ATOM 3669 O OH . TYR D 1 58 ? -18.393 -10.221 13.917 1.00 38.81 ? 278 TYR D OH 1 ATOM 3670 N N . VAL D 1 59 ? -17.523 -10.334 5.288 1.00 36.02 ? 279 VAL D N 1 ATOM 3671 C CA . VAL D 1 59 ? -17.502 -10.727 3.880 1.00 40.88 ? 279 VAL D CA 1 ATOM 3672 C C . VAL D 1 59 ? -16.604 -11.967 3.742 1.00 41.30 ? 279 VAL D C 1 ATOM 3673 O O . VAL D 1 59 ? -15.388 -11.885 3.947 1.00 46.22 ? 279 VAL D O 1 ATOM 3674 C CB . VAL D 1 59 ? -17.052 -9.550 2.980 1.00 37.84 ? 279 VAL D CB 1 ATOM 3675 C CG1 . VAL D 1 59 ? -17.032 -9.957 1.512 1.00 38.38 ? 279 VAL D CG1 1 ATOM 3676 C CG2 . VAL D 1 59 ? -17.978 -8.358 3.177 1.00 33.56 ? 279 VAL D CG2 1 ATOM 3677 N N . ASP D 1 60 ? -17.215 -13.109 3.415 1.00 39.28 ? 280 ASP D N 1 ATOM 3678 C CA . ASP D 1 60 ? -16.569 -14.427 3.536 1.00 34.32 ? 280 ASP D CA 1 ATOM 3679 C C . ASP D 1 60 ? -15.835 -14.570 4.881 1.00 37.58 ? 280 ASP D C 1 ATOM 3680 O O . ASP D 1 60 ? -14.679 -14.972 4.926 1.00 38.32 ? 280 ASP D O 1 ATOM 3681 C CB . ASP D 1 60 ? -15.604 -14.690 2.370 1.00 33.42 ? 280 ASP D CB 1 ATOM 3682 C CG . ASP D 1 60 ? -16.324 -14.991 1.046 1.00 38.71 ? 280 ASP D CG 1 ATOM 3683 O OD1 . ASP D 1 60 ? -17.527 -15.320 1.042 1.00 38.70 ? 280 ASP D OD1 1 ATOM 3684 O OD2 . ASP D 1 60 ? -15.666 -14.906 -0.009 1.00 42.59 ? 280 ASP D OD2 1 ATOM 3685 N N . GLY D 1 61 ? -16.506 -14.210 5.971 1.00 39.41 ? 281 GLY D N 1 ATOM 3686 C CA . GLY D 1 61 ? -15.965 -14.404 7.317 1.00 38.24 ? 281 GLY D CA 1 ATOM 3687 C C . GLY D 1 61 ? -15.118 -13.273 7.862 1.00 39.59 ? 281 GLY D C 1 ATOM 3688 O O . GLY D 1 61 ? -14.856 -13.224 9.065 1.00 49.18 ? 281 GLY D O 1 ATOM 3689 N N . VAL D 1 62 ? -14.700 -12.358 6.992 1.00 37.24 ? 282 VAL D N 1 ATOM 3690 C CA . VAL D 1 62 ? -13.799 -11.267 7.377 1.00 41.58 ? 282 VAL D CA 1 ATOM 3691 C C . VAL D 1 62 ? -14.555 -9.963 7.610 1.00 45.09 ? 282 VAL D C 1 ATOM 3692 O O . VAL D 1 62 ? -15.190 -9.432 6.698 1.00 44.96 ? 282 VAL D O 1 ATOM 3693 C CB . VAL D 1 62 ? -12.706 -11.033 6.313 1.00 48.04 ? 282 VAL D CB 1 ATOM 3694 C CG1 . VAL D 1 62 ? -11.699 -9.989 6.791 1.00 39.98 ? 282 VAL D CG1 1 ATOM 3695 C CG2 . VAL D 1 62 ? -12.011 -12.350 5.969 1.00 49.24 ? 282 VAL D CG2 1 ATOM 3696 N N . GLU D 1 63 ? -14.466 -9.446 8.829 1.00 40.02 ? 283 GLU D N 1 ATOM 3697 C CA . GLU D 1 63 ? -15.184 -8.234 9.201 1.00 46.31 ? 283 GLU D CA 1 ATOM 3698 C C . GLU D 1 63 ? -14.811 -7.052 8.300 1.00 48.87 ? 283 GLU D C 1 ATOM 3699 O O . GLU D 1 63 ? -13.632 -6.785 8.065 1.00 54.03 ? 283 GLU D O 1 ATOM 3700 C CB . GLU D 1 63 ? -14.956 -7.901 10.688 1.00 42.79 ? 283 GLU D CB 1 ATOM 3701 C CG . GLU D 1 63 ? -15.968 -6.922 11.274 1.00 47.18 ? 283 GLU D CG 1 ATOM 3702 C CD . GLU D 1 63 ? -15.982 -6.877 12.798 1.00 48.55 ? 283 GLU D CD 1 ATOM 3703 O OE1 . GLU D 1 63 ? -15.195 -7.594 13.442 1.00 48.72 ? 283 GLU D OE1 1 ATOM 3704 O OE2 . GLU D 1 63 ? -16.800 -6.122 13.364 1.00 50.41 ? 283 GLU D OE2 1 ATOM 3705 N N . VAL D 1 64 ? -15.832 -6.381 7.770 1.00 44.06 ? 284 VAL D N 1 ATOM 3706 C CA . VAL D 1 64 ? -15.666 -5.098 7.081 1.00 36.63 ? 284 VAL D CA 1 ATOM 3707 C C . VAL D 1 64 ? -16.272 -4.000 7.959 1.00 46.52 ? 284 VAL D C 1 ATOM 3708 O O . VAL D 1 64 ? -17.105 -4.286 8.827 1.00 51.00 ? 284 VAL D O 1 ATOM 3709 C CB . VAL D 1 64 ? -16.322 -5.097 5.685 1.00 38.50 ? 284 VAL D CB 1 ATOM 3710 C CG1 . VAL D 1 64 ? -15.599 -6.069 4.750 1.00 28.44 ? 284 VAL D CG1 1 ATOM 3711 C CG2 . VAL D 1 64 ? -17.810 -5.431 5.779 1.00 36.63 ? 284 VAL D CG2 1 ATOM 3712 N N . HIS D 1 65 ? -15.864 -2.752 7.745 1.00 35.97 ? 285 HIS D N 1 ATOM 3713 C CA . HIS D 1 65 ? -16.271 -1.666 8.642 1.00 34.67 ? 285 HIS D CA 1 ATOM 3714 C C . HIS D 1 65 ? -16.946 -0.502 7.966 1.00 34.06 ? 285 HIS D C 1 ATOM 3715 O O . HIS D 1 65 ? -17.218 0.509 8.605 1.00 30.09 ? 285 HIS D O 1 ATOM 3716 C CB . HIS D 1 65 ? -15.067 -1.189 9.458 1.00 39.82 ? 285 HIS D CB 1 ATOM 3717 C CG . HIS D 1 65 ? -14.574 -2.203 10.466 1.00 38.79 ? 285 HIS D CG 1 ATOM 3718 N ND1 . HIS D 1 65 ? -13.827 -3.268 10.118 1.00 37.76 ? 285 HIS D ND1 1 ATOM 3719 C CD2 . HIS D 1 65 ? -14.757 -2.286 11.845 1.00 42.73 ? 285 HIS D CD2 1 ATOM 3720 C CE1 . HIS D 1 65 ? -13.543 -3.996 11.213 1.00 36.86 ? 285 HIS D CE1 1 ATOM 3721 N NE2 . HIS D 1 65 ? -14.110 -3.393 12.271 1.00 41.54 ? 285 HIS D NE2 1 ATOM 3722 N N . ASN D 1 66 ? -17.242 -0.620 6.672 1.00 28.26 ? 286 ASN D N 1 ATOM 3723 C CA . ASN D 1 66 ? -17.786 0.517 5.941 1.00 27.88 ? 286 ASN D CA 1 ATOM 3724 C C . ASN D 1 66 ? -19.322 0.556 5.799 1.00 34.09 ? 286 ASN D C 1 ATOM 3725 O O . ASN D 1 66 ? -19.846 1.262 4.929 1.00 36.25 ? 286 ASN D O 1 ATOM 3726 C CB . ASN D 1 66 ? -17.141 0.592 4.565 1.00 31.74 ? 286 ASN D CB 1 ATOM 3727 C CG . ASN D 1 66 ? -17.420 -0.635 3.744 1.00 33.41 ? 286 ASN D CG 1 ATOM 3728 O OD1 . ASN D 1 66 ? -17.381 -1.755 4.258 1.00 32.55 ? 286 ASN D OD1 1 ATOM 3729 N ND2 . ASN D 1 66 ? -17.718 -0.440 2.462 1.00 45.64 ? 286 ASN D ND2 1 ATOM 3730 N N . ALA D 1 67 ? -20.043 -0.191 6.637 1.00 30.19 ? 287 ALA D N 1 ATOM 3731 C CA . ALA D 1 67 ? -21.508 -0.148 6.589 1.00 29.32 ? 287 ALA D CA 1 ATOM 3732 C C . ALA D 1 67 ? -22.037 1.150 7.185 1.00 31.27 ? 287 ALA D C 1 ATOM 3733 O O . ALA D 1 67 ? -21.341 1.843 7.927 1.00 47.21 ? 287 ALA D O 1 ATOM 3734 C CB . ALA D 1 67 ? -22.131 -1.356 7.273 1.00 25.04 ? 287 ALA D CB 1 ATOM 3735 N N . LYS D 1 68 ? -23.271 1.478 6.835 1.00 36.08 ? 288 LYS D N 1 ATOM 3736 C CA . LYS D 1 68 ? -23.878 2.739 7.207 1.00 35.48 ? 288 LYS D CA 1 ATOM 3737 C C . LYS D 1 68 ? -25.275 2.445 7.703 1.00 32.87 ? 288 LYS D C 1 ATOM 3738 O O . LYS D 1 68 ? -26.052 1.764 7.031 1.00 28.94 ? 288 LYS D O 1 ATOM 3739 C CB . LYS D 1 68 ? -23.909 3.705 6.010 1.00 38.03 ? 288 LYS D CB 1 ATOM 3740 C CG . LYS D 1 68 ? -22.533 4.205 5.591 1.00 38.60 ? 288 LYS D CG 1 ATOM 3741 C CD . LYS D 1 68 ? -22.581 5.077 4.351 1.00 47.56 ? 288 LYS D CD 1 ATOM 3742 C CE . LYS D 1 68 ? -21.186 5.557 3.973 1.00 53.16 ? 288 LYS D CE 1 ATOM 3743 N N . THR D 1 69 ? -25.571 2.923 8.907 1.00 26.55 ? 289 THR D N 1 ATOM 3744 C CA . THR D 1 69 ? -26.893 2.786 9.467 1.00 28.46 ? 289 THR D CA 1 ATOM 3745 C C . THR D 1 69 ? -27.806 3.868 8.957 1.00 29.52 ? 289 THR D C 1 ATOM 3746 O O . THR D 1 69 ? -27.499 5.058 9.092 1.00 27.28 ? 289 THR D O 1 ATOM 3747 C CB . THR D 1 69 ? -26.869 2.902 10.993 1.00 25.34 ? 289 THR D CB 1 ATOM 3748 O OG1 . THR D 1 69 ? -25.762 2.160 11.488 1.00 23.21 ? 289 THR D OG1 1 ATOM 3749 C CG2 . THR D 1 69 ? -28.147 2.353 11.577 1.00 22.35 ? 289 THR D CG2 1 ATOM 3750 N N . LYS D 1 70 ? -28.938 3.447 8.396 1.00 31.76 ? 290 LYS D N 1 ATOM 3751 C CA . LYS D 1 70 ? -29.989 4.374 7.969 1.00 31.56 ? 290 LYS D CA 1 ATOM 3752 C C . LYS D 1 70 ? -30.591 5.080 9.188 1.00 34.32 ? 290 LYS D C 1 ATOM 3753 O O . LYS D 1 70 ? -30.385 4.635 10.320 1.00 34.89 ? 290 LYS D O 1 ATOM 3754 C CB . LYS D 1 70 ? -31.057 3.644 7.159 1.00 29.51 ? 290 LYS D CB 1 ATOM 3755 C CG . LYS D 1 70 ? -30.570 3.184 5.794 1.00 36.80 ? 290 LYS D CG 1 ATOM 3756 C CD . LYS D 1 70 ? -31.725 2.840 4.866 1.00 47.00 ? 290 LYS D CD 1 ATOM 3757 C CE . LYS D 1 70 ? -32.017 3.976 3.892 1.00 64.96 ? 290 LYS D CE 1 ATOM 3758 N NZ . LYS D 1 70 ? -30.990 4.069 2.813 1.00 61.55 ? 290 LYS D NZ 1 ATOM 3759 N N . PRO D 1 71 ? -31.295 6.211 8.972 1.00 38.67 ? 291 PRO D N 1 ATOM 3760 C CA . PRO D 1 71 ? -31.955 6.850 10.119 1.00 33.18 ? 291 PRO D CA 1 ATOM 3761 C C . PRO D 1 71 ? -33.030 5.935 10.727 1.00 31.90 ? 291 PRO D C 1 ATOM 3762 O O . PRO D 1 71 ? -33.773 5.267 10.002 1.00 23.47 ? 291 PRO D O 1 ATOM 3763 C CB . PRO D 1 71 ? -32.592 8.110 9.514 1.00 37.09 ? 291 PRO D CB 1 ATOM 3764 C CG . PRO D 1 71 ? -31.895 8.327 8.205 1.00 34.12 ? 291 PRO D CG 1 ATOM 3765 C CD . PRO D 1 71 ? -31.485 6.973 7.718 1.00 33.40 ? 291 PRO D CD 1 ATOM 3766 N N . ARG D 1 72 ? -33.088 5.907 12.051 1.00 24.72 ? 292 ARG D N 1 ATOM 3767 C CA . ARG D 1 72 ? -34.042 5.106 12.798 1.00 24.01 ? 292 ARG D CA 1 ATOM 3768 C C . ARG D 1 72 ? -35.477 5.485 12.436 1.00 28.07 ? 292 ARG D C 1 ATOM 3769 O O . ARG D 1 72 ? -35.776 6.660 12.214 1.00 31.75 ? 292 ARG D O 1 ATOM 3770 C CB . ARG D 1 72 ? -33.811 5.350 14.302 1.00 21.77 ? 292 ARG D CB 1 ATOM 3771 C CG . ARG D 1 72 ? -34.610 4.440 15.222 1.00 24.35 ? 292 ARG D CG 1 ATOM 3772 C CD . ARG D 1 72 ? -34.162 4.623 16.672 1.00 25.09 ? 292 ARG D CD 1 ATOM 3773 N NE . ARG D 1 72 ? -34.743 5.827 17.238 1.00 31.82 ? 292 ARG D NE 1 ATOM 3774 C CZ . ARG D 1 72 ? -34.493 6.292 18.459 1.00 36.05 ? 292 ARG D CZ 1 ATOM 3775 N NH1 . ARG D 1 72 ? -33.652 5.662 19.268 1.00 38.01 ? 292 ARG D NH1 1 ATOM 3776 N NH2 . ARG D 1 72 ? -35.093 7.397 18.864 1.00 32.72 ? 292 ARG D NH2 1 ATOM 3777 N N . GLU D 1 73 ? -36.371 4.506 12.401 1.00 27.26 ? 293 GLU D N 1 ATOM 3778 C CA . GLU D 1 73 ? -37.739 4.771 11.980 1.00 33.52 ? 293 GLU D CA 1 ATOM 3779 C C . GLU D 1 73 ? -38.769 4.194 12.952 1.00 36.05 ? 293 GLU D C 1 ATOM 3780 O O . GLU D 1 73 ? -38.867 2.974 13.135 1.00 33.57 ? 293 GLU D O 1 ATOM 3781 C CB . GLU D 1 73 ? -37.957 4.250 10.546 1.00 43.66 ? 293 GLU D CB 1 ATOM 3782 C CG . GLU D 1 73 ? -38.850 5.123 9.672 1.00 54.99 ? 293 GLU D CG 1 ATOM 3783 C CD . GLU D 1 73 ? -38.435 6.589 9.651 1.00 54.21 ? 293 GLU D CD 1 ATOM 3784 O OE1 . GLU D 1 73 ? -37.349 6.915 9.119 1.00 51.65 ? 293 GLU D OE1 1 ATOM 3785 O OE2 . GLU D 1 73 ? -39.211 7.417 10.170 1.00 55.46 ? 293 GLU D OE2 1 ATOM 3786 N N . GLU D 1 74 ? -39.509 5.098 13.592 1.00 40.44 ? 294 GLU D N 1 ATOM 3787 C CA . GLU D 1 74 ? -40.647 4.758 14.442 1.00 39.42 ? 294 GLU D CA 1 ATOM 3788 C C . GLU D 1 74 ? -41.749 4.081 13.632 1.00 36.73 ? 294 GLU D C 1 ATOM 3789 O O . GLU D 1 74 ? -42.146 4.592 12.585 1.00 36.67 ? 294 GLU D O 1 ATOM 3790 C CB . GLU D 1 74 ? -41.196 6.025 15.088 1.00 42.88 ? 294 GLU D CB 1 ATOM 3791 C CG . GLU D 1 74 ? -42.514 5.833 15.811 1.00 55.47 ? 294 GLU D CG 1 ATOM 3792 C CD . GLU D 1 74 ? -42.368 4.973 17.043 1.00 59.27 ? 294 GLU D CD 1 ATOM 3793 O OE1 . GLU D 1 74 ? -42.704 3.768 16.974 1.00 58.08 ? 294 GLU D OE1 1 ATOM 3794 O OE2 . GLU D 1 74 ? -41.891 5.506 18.065 1.00 52.88 ? 294 GLU D OE2 1 ATOM 3795 N N . GLN D 1 75 ? -42.244 2.942 14.119 1.00 36.15 ? 295 GLN D N 1 ATOM 3796 C CA . GLN D 1 75 ? -43.239 2.149 13.377 1.00 35.07 ? 295 GLN D CA 1 ATOM 3797 C C . GLN D 1 75 ? -44.681 2.368 13.836 1.00 34.96 ? 295 GLN D C 1 ATOM 3798 O O . GLN D 1 75 ? -45.617 2.024 13.115 1.00 34.86 ? 295 GLN D O 1 ATOM 3799 C CB . GLN D 1 75 ? -42.877 0.657 13.385 1.00 33.10 ? 295 GLN D CB 1 ATOM 3800 C CG . GLN D 1 75 ? -41.560 0.352 12.694 1.00 33.01 ? 295 GLN D CG 1 ATOM 3801 C CD . GLN D 1 75 ? -41.545 0.825 11.245 1.00 39.23 ? 295 GLN D CD 1 ATOM 3802 O OE1 . GLN D 1 75 ? -42.283 0.313 10.396 1.00 38.18 ? 295 GLN D OE1 1 ATOM 3803 N NE2 . GLN D 1 75 ? -40.702 1.806 10.957 1.00 33.75 ? 295 GLN D NE2 1 ATOM 3804 N N . TYR D 1 76 ? -44.825 2.937 15.033 1.00 30.93 ? 296 TYR D N 1 ATOM 3805 C CA . TYR D 1 76 ? -46.095 3.331 15.660 1.00 36.42 ? 296 TYR D CA 1 ATOM 3806 C C . TYR D 1 76 ? -46.895 2.166 16.261 1.00 42.34 ? 296 TYR D C 1 ATOM 3807 O O . TYR D 1 76 ? -47.978 2.360 16.822 1.00 40.63 ? 296 TYR D O 1 ATOM 3808 C CB . TYR D 1 76 ? -46.931 4.250 14.743 1.00 33.24 ? 296 TYR D CB 1 ATOM 3809 C CG . TYR D 1 76 ? -46.222 5.555 14.421 1.00 32.82 ? 296 TYR D CG 1 ATOM 3810 C CD1 . TYR D 1 76 ? -46.024 6.528 15.408 1.00 28.95 ? 296 TYR D CD1 1 ATOM 3811 C CD2 . TYR D 1 76 ? -45.731 5.809 13.135 1.00 29.83 ? 296 TYR D CD2 1 ATOM 3812 C CE1 . TYR D 1 76 ? -45.369 7.714 15.125 1.00 32.11 ? 296 TYR D CE1 1 ATOM 3813 C CE2 . TYR D 1 76 ? -45.071 6.991 12.842 1.00 31.52 ? 296 TYR D CE2 1 ATOM 3814 C CZ . TYR D 1 76 ? -44.898 7.943 13.840 1.00 43.65 ? 296 TYR D CZ 1 ATOM 3815 O OH . TYR D 1 76 ? -44.243 9.126 13.564 1.00 54.39 ? 296 TYR D OH 1 ATOM 3816 N N . ASN D 1 77 ? -46.318 0.968 16.172 1.00 39.62 ? 297 ASN D N 1 ATOM 3817 C CA . ASN D 1 77 ? -46.883 -0.239 16.765 1.00 36.32 ? 297 ASN D CA 1 ATOM 3818 C C . ASN D 1 77 ? -46.126 -0.733 18.002 1.00 34.60 ? 297 ASN D C 1 ATOM 3819 O O . ASN D 1 77 ? -46.225 -1.902 18.362 1.00 43.57 ? 297 ASN D O 1 ATOM 3820 C CB . ASN D 1 77 ? -46.918 -1.355 15.731 1.00 35.28 ? 297 ASN D CB 1 ATOM 3821 C CG . ASN D 1 77 ? -45.539 -1.734 15.227 1.00 40.81 ? 297 ASN D CG 1 ATOM 3822 O OD1 . ASN D 1 77 ? -44.519 -1.193 15.664 1.00 43.65 ? 297 ASN D OD1 1 ATOM 3823 N ND2 . ASN D 1 77 ? -45.506 -2.673 14.300 1.00 37.27 ? 297 ASN D ND2 1 ATOM 3824 N N . SER D 1 78 ? -45.354 0.155 18.626 1.00 38.56 ? 298 SER D N 1 ATOM 3825 C CA . SER D 1 78 ? -44.570 -0.181 19.820 1.00 48.30 ? 298 SER D CA 1 ATOM 3826 C C . SER D 1 78 ? -43.072 -0.266 19.516 1.00 43.26 ? 298 SER D C 1 ATOM 3827 O O . SER D 1 78 ? -42.247 -0.146 20.418 1.00 41.85 ? 298 SER D O 1 ATOM 3828 C CB . SER D 1 78 ? -45.047 -1.497 20.450 1.00 37.78 ? 298 SER D CB 1 ATOM 3829 O OG . SER D 1 78 ? -44.492 -1.662 21.737 1.00 55.78 ? 298 SER D OG 1 ATOM 3830 N N . THR D 1 79 ? -42.732 -0.465 18.244 1.00 40.41 ? 299 THR D N 1 ATOM 3831 C CA . THR D 1 79 ? -41.360 -0.791 17.865 1.00 38.34 ? 299 THR D CA 1 ATOM 3832 C C . THR D 1 79 ? -40.676 0.228 16.944 1.00 40.00 ? 299 THR D C 1 ATOM 3833 O O . THR D 1 79 ? -41.334 1.045 16.299 1.00 44.34 ? 299 THR D O 1 ATOM 3834 C CB . THR D 1 79 ? -41.306 -2.185 17.211 1.00 36.80 ? 299 THR D CB 1 ATOM 3835 O OG1 . THR D 1 79 ? -41.966 -2.143 15.942 1.00 40.96 ? 299 THR D OG1 1 ATOM 3836 C CG2 . THR D 1 79 ? -41.990 -3.221 18.102 1.00 31.54 ? 299 THR D CG2 1 ATOM 3837 N N . TYR D 1 80 ? -39.344 0.172 16.908 1.00 41.15 ? 300 TYR D N 1 ATOM 3838 C CA . TYR D 1 80 ? -38.556 0.824 15.862 1.00 32.99 ? 300 TYR D CA 1 ATOM 3839 C C . TYR D 1 80 ? -38.137 -0.181 14.801 1.00 32.36 ? 300 TYR D C 1 ATOM 3840 O O . TYR D 1 80 ? -38.053 -1.389 15.058 1.00 27.64 ? 300 TYR D O 1 ATOM 3841 C CB . TYR D 1 80 ? -37.272 1.434 16.417 1.00 27.62 ? 300 TYR D CB 1 ATOM 3842 C CG . TYR D 1 80 ? -37.468 2.596 17.343 1.00 30.13 ? 300 TYR D CG 1 ATOM 3843 C CD1 . TYR D 1 80 ? -37.179 2.476 18.703 1.00 30.30 ? 300 TYR D CD1 1 ATOM 3844 C CD2 . TYR D 1 80 ? -37.929 3.826 16.862 1.00 30.40 ? 300 TYR D CD2 1 ATOM 3845 C CE1 . TYR D 1 80 ? -37.347 3.552 19.563 1.00 32.88 ? 300 TYR D CE1 1 ATOM 3846 C CE2 . TYR D 1 80 ? -38.098 4.905 17.708 1.00 29.84 ? 300 TYR D CE2 1 ATOM 3847 C CZ . TYR D 1 80 ? -37.810 4.757 19.059 1.00 32.51 ? 300 TYR D CZ 1 ATOM 3848 O OH . TYR D 1 80 ? -37.977 5.821 19.910 1.00 36.05 ? 300 TYR D OH 1 ATOM 3849 N N . ARG D 1 81 ? -37.854 0.349 13.617 1.00 26.14 ? 301 ARG D N 1 ATOM 3850 C CA . ARG D 1 81 ? -37.186 -0.377 12.570 1.00 26.12 ? 301 ARG D CA 1 ATOM 3851 C C . ARG D 1 81 ? -35.767 0.216 12.468 1.00 27.07 ? 301 ARG D C 1 ATOM 3852 O O . ARG D 1 81 ? -35.596 1.445 12.448 1.00 26.68 ? 301 ARG D O 1 ATOM 3853 C CB . ARG D 1 81 ? -37.956 -0.181 11.263 1.00 22.54 ? 301 ARG D CB 1 ATOM 3854 C CG . ARG D 1 81 ? -37.522 -1.085 10.134 1.00 28.61 ? 301 ARG D CG 1 ATOM 3855 C CD . ARG D 1 81 ? -38.369 -0.777 8.918 1.00 29.06 ? 301 ARG D CD 1 ATOM 3856 N NE . ARG D 1 81 ? -38.177 -1.715 7.814 1.00 28.47 ? 301 ARG D NE 1 ATOM 3857 C CZ . ARG D 1 81 ? -37.594 -1.405 6.659 1.00 31.12 ? 301 ARG D CZ 1 ATOM 3858 N NH1 . ARG D 1 81 ? -37.112 -0.190 6.468 1.00 28.75 ? 301 ARG D NH1 1 ATOM 3859 N NH2 . ARG D 1 81 ? -37.482 -2.315 5.696 1.00 26.51 ? 301 ARG D NH2 1 ATOM 3860 N N . VAL D 1 82 ? -34.760 -0.659 12.426 1.00 27.44 ? 302 VAL D N 1 ATOM 3861 C CA . VAL D 1 82 ? -33.349 -0.255 12.375 1.00 26.22 ? 302 VAL D CA 1 ATOM 3862 C C . VAL D 1 82 ? -32.677 -0.934 11.181 1.00 26.42 ? 302 VAL D C 1 ATOM 3863 O O . VAL D 1 82 ? -32.825 -2.146 10.988 1.00 27.97 ? 302 VAL D O 1 ATOM 3864 C CB . VAL D 1 82 ? -32.610 -0.595 13.696 1.00 27.83 ? 302 VAL D CB 1 ATOM 3865 C CG1 . VAL D 1 82 ? -31.142 -0.192 13.629 1.00 26.01 ? 302 VAL D CG1 1 ATOM 3866 C CG2 . VAL D 1 82 ? -33.271 0.093 14.889 1.00 22.15 ? 302 VAL D CG2 1 ATOM 3867 N N . VAL D 1 83 ? -31.943 -0.165 10.380 1.00 27.77 ? 303 VAL D N 1 ATOM 3868 C CA . VAL D 1 83 ? -31.414 -0.670 9.088 1.00 22.04 ? 303 VAL D CA 1 ATOM 3869 C C . VAL D 1 83 ? -29.930 -0.330 8.860 1.00 22.96 ? 303 VAL D C 1 ATOM 3870 O O . VAL D 1 83 ? -29.544 0.840 8.896 1.00 22.91 ? 303 VAL D O 1 ATOM 3871 C CB . VAL D 1 83 ? -32.279 -0.176 7.905 1.00 22.56 ? 303 VAL D CB 1 ATOM 3872 C CG1 . VAL D 1 83 ? -31.775 -0.717 6.566 1.00 17.11 ? 303 VAL D CG1 1 ATOM 3873 C CG2 . VAL D 1 83 ? -33.733 -0.584 8.112 1.00 22.51 ? 303 VAL D CG2 1 ATOM 3874 N N . SER D 1 84 ? -29.096 -1.358 8.673 1.00 22.65 ? 304 SER D N 1 ATOM 3875 C CA . SER D 1 84 ? -27.718 -1.149 8.239 1.00 22.71 ? 304 SER D CA 1 ATOM 3876 C C . SER D 1 84 ? -27.651 -1.473 6.757 1.00 25.76 ? 304 SER D C 1 ATOM 3877 O O . SER D 1 84 ? -28.238 -2.445 6.329 1.00 20.03 ? 304 SER D O 1 ATOM 3878 C CB . SER D 1 84 ? -26.763 -2.065 8.977 1.00 25.67 ? 304 SER D CB 1 ATOM 3879 O OG . SER D 1 84 ? -25.422 -1.775 8.603 1.00 29.19 ? 304 SER D OG 1 ATOM 3880 N N . VAL D 1 85 ? -26.951 -0.651 5.983 1.00 26.34 ? 305 VAL D N 1 ATOM 3881 C CA . VAL D 1 85 ? -26.776 -0.899 4.545 1.00 28.85 ? 305 VAL D CA 1 ATOM 3882 C C . VAL D 1 85 ? -25.274 -0.997 4.246 1.00 31.03 ? 305 VAL D C 1 ATOM 3883 O O . VAL D 1 85 ? -24.495 -0.124 4.653 1.00 37.96 ? 305 VAL D O 1 ATOM 3884 C CB . VAL D 1 85 ? -27.428 0.215 3.689 1.00 29.16 ? 305 VAL D CB 1 ATOM 3885 C CG1 . VAL D 1 85 ? -27.112 0.028 2.206 1.00 33.13 ? 305 VAL D CG1 1 ATOM 3886 C CG2 . VAL D 1 85 ? -28.945 0.256 3.893 1.00 25.06 ? 305 VAL D CG2 1 ATOM 3887 N N . LEU D 1 86 ? -24.878 -2.073 3.566 1.00 27.98 ? 306 LEU D N 1 ATOM 3888 C CA . LEU D 1 86 ? -23.491 -2.306 3.149 1.00 29.30 ? 306 LEU D CA 1 ATOM 3889 C C . LEU D 1 86 ? -23.349 -2.353 1.622 1.00 38.42 ? 306 LEU D C 1 ATOM 3890 O O . LEU D 1 86 ? -23.910 -3.239 0.978 1.00 25.83 ? 306 LEU D O 1 ATOM 3891 C CB . LEU D 1 86 ? -22.974 -3.639 3.711 1.00 29.05 ? 306 LEU D CB 1 ATOM 3892 C CG . LEU D 1 86 ? -21.624 -4.198 3.200 1.00 26.36 ? 306 LEU D CG 1 ATOM 3893 C CD1 . LEU D 1 86 ? -20.442 -3.291 3.471 1.00 27.64 ? 306 LEU D CD1 1 ATOM 3894 C CD2 . LEU D 1 86 ? -21.351 -5.565 3.799 1.00 30.97 ? 306 LEU D CD2 1 ATOM 3895 N N . THR D 1 87 ? -22.565 -1.426 1.071 1.00 38.05 ? 307 THR D N 1 ATOM 3896 C CA . THR D 1 87 ? -22.201 -1.439 -0.343 1.00 31.22 ? 307 THR D CA 1 ATOM 3897 C C . THR D 1 87 ? -21.363 -2.673 -0.651 1.00 32.82 ? 307 THR D C 1 ATOM 3898 O O . THR D 1 87 ? -20.506 -3.071 0.136 1.00 28.84 ? 307 THR D O 1 ATOM 3899 C CB . THR D 1 87 ? -21.425 -0.158 -0.729 1.00 30.71 ? 307 THR D CB 1 ATOM 3900 O OG1 . THR D 1 87 ? -22.289 0.968 -0.580 1.00 38.70 ? 307 THR D OG1 1 ATOM 3901 C CG2 . THR D 1 87 ? -20.925 -0.194 -2.180 1.00 34.98 ? 307 THR D CG2 1 ATOM 3902 N N . VAL D 1 88 ? -21.644 -3.292 -1.791 1.00 28.15 ? 308 VAL D N 1 ATOM 3903 C CA . VAL D 1 88 ? -20.872 -4.413 -2.250 1.00 32.19 ? 308 VAL D CA 1 ATOM 3904 C C . VAL D 1 88 ? -20.354 -4.128 -3.668 1.00 41.67 ? 308 VAL D C 1 ATOM 3905 O O . VAL D 1 88 ? -21.002 -3.427 -4.458 1.00 32.29 ? 308 VAL D O 1 ATOM 3906 C CB . VAL D 1 88 ? -21.672 -5.751 -2.204 1.00 34.58 ? 308 VAL D CB 1 ATOM 3907 C CG1 . VAL D 1 88 ? -22.424 -5.901 -0.891 1.00 32.78 ? 308 VAL D CG1 1 ATOM 3908 C CG2 . VAL D 1 88 ? -22.634 -5.872 -3.375 1.00 29.92 ? 308 VAL D CG2 1 ATOM 3909 N N . LEU D 1 89 ? -19.181 -4.672 -3.976 1.00 40.00 ? 309 LEU D N 1 ATOM 3910 C CA . LEU D 1 89 ? -18.607 -4.550 -5.302 1.00 36.34 ? 309 LEU D CA 1 ATOM 3911 C C . LEU D 1 89 ? -19.286 -5.558 -6.218 1.00 34.92 ? 309 LEU D C 1 ATOM 3912 O O . LEU D 1 89 ? -19.558 -6.696 -5.821 1.00 34.45 ? 309 LEU D O 1 ATOM 3913 C CB . LEU D 1 89 ? -17.093 -4.768 -5.248 1.00 37.25 ? 309 LEU D CB 1 ATOM 3914 C CG . LEU D 1 89 ? -16.366 -3.894 -4.214 1.00 31.93 ? 309 LEU D CG 1 ATOM 3915 C CD1 . LEU D 1 89 ? -14.917 -4.318 -4.023 1.00 33.30 ? 309 LEU D CD1 1 ATOM 3916 C CD2 . LEU D 1 89 ? -16.457 -2.421 -4.590 1.00 31.44 ? 309 LEU D CD2 1 ATOM 3917 N N . HIS D 1 90 ? -19.579 -5.124 -7.438 1.00 31.68 ? 310 HIS D N 1 ATOM 3918 C CA . HIS D 1 90 ? -20.276 -5.962 -8.413 1.00 31.52 ? 310 HIS D CA 1 ATOM 3919 C C . HIS D 1 90 ? -19.694 -7.337 -8.518 1.00 34.30 ? 310 HIS D C 1 ATOM 3920 O O . HIS D 1 90 ? -20.431 -8.322 -8.503 1.00 41.04 ? 310 HIS D O 1 ATOM 3921 C CB . HIS D 1 90 ? -20.283 -5.291 -9.783 1.00 25.77 ? 310 HIS D CB 1 ATOM 3922 C CG . HIS D 1 90 ? -20.934 -3.938 -9.780 1.00 23.40 ? 310 HIS D CG 1 ATOM 3923 N ND1 . HIS D 1 90 ? -20.280 -2.822 -9.401 1.00 25.06 ? 310 HIS D ND1 1 ATOM 3924 C CD2 . HIS D 1 90 ? -22.230 -3.549 -10.103 1.00 21.28 ? 310 HIS D CD2 1 ATOM 3925 C CE1 . HIS D 1 90 ? -21.105 -1.767 -9.492 1.00 26.20 ? 310 HIS D CE1 1 ATOM 3926 N NE2 . HIS D 1 90 ? -22.305 -2.212 -9.925 1.00 25.97 ? 310 HIS D NE2 1 ATOM 3927 N N . GLN D 1 91 ? -18.367 -7.419 -8.614 1.00 39.39 ? 311 GLN D N 1 ATOM 3928 C CA . GLN D 1 91 ? -17.713 -8.705 -8.859 1.00 42.02 ? 311 GLN D CA 1 ATOM 3929 C C . GLN D 1 91 ? -17.704 -9.652 -7.661 1.00 38.38 ? 311 GLN D C 1 ATOM 3930 O O . GLN D 1 91 ? -17.893 -10.850 -7.848 1.00 39.22 ? 311 GLN D O 1 ATOM 3931 C CB . GLN D 1 91 ? -16.318 -8.534 -9.459 1.00 49.76 ? 311 GLN D CB 1 ATOM 3932 C CG . GLN D 1 91 ? -16.330 -8.351 -10.975 1.00 55.28 ? 311 GLN D CG 1 ATOM 3933 C CD . GLN D 1 91 ? -16.964 -9.513 -11.739 1.00 62.22 ? 311 GLN D CD 1 ATOM 3934 O OE1 . GLN D 1 91 ? -17.303 -10.553 -11.170 1.00 77.92 ? 311 GLN D OE1 1 ATOM 3935 N NE2 . GLN D 1 91 ? -17.121 -9.338 -13.042 1.00 69.30 ? 311 GLN D NE2 1 ATOM 3936 N N . ASP D 1 92 ? -17.514 -9.115 -6.449 1.00 33.38 ? 312 ASP D N 1 ATOM 3937 C CA . ASP D 1 92 ? -17.655 -9.898 -5.212 1.00 33.04 ? 312 ASP D CA 1 ATOM 3938 C C . ASP D 1 92 ? -18.989 -10.632 -5.165 1.00 35.42 ? 312 ASP D C 1 ATOM 3939 O O . ASP D 1 92 ? -19.041 -11.828 -4.857 1.00 35.14 ? 312 ASP D O 1 ATOM 3940 C CB . ASP D 1 92 ? -17.520 -9.008 -3.970 1.00 33.01 ? 312 ASP D CB 1 ATOM 3941 C CG . ASP D 1 92 ? -16.101 -8.531 -3.744 1.00 40.15 ? 312 ASP D CG 1 ATOM 3942 O OD1 . ASP D 1 92 ? -15.193 -9.003 -4.462 1.00 48.14 ? 312 ASP D OD1 1 ATOM 3943 O OD2 . ASP D 1 92 ? -15.887 -7.688 -2.845 1.00 39.53 ? 312 ASP D OD2 1 ATOM 3944 N N . TRP D 1 93 ? -20.063 -9.911 -5.487 1.00 34.62 ? 313 TRP D N 1 ATOM 3945 C CA . TRP D 1 93 ? -21.388 -10.492 -5.470 1.00 31.96 ? 313 TRP D CA 1 ATOM 3946 C C . TRP D 1 93 ? -21.506 -11.526 -6.544 1.00 36.23 ? 313 TRP D C 1 ATOM 3947 O O . TRP D 1 93 ? -22.046 -12.615 -6.312 1.00 32.22 ? 313 TRP D O 1 ATOM 3948 C CB . TRP D 1 93 ? -22.477 -9.433 -5.648 1.00 35.71 ? 313 TRP D CB 1 ATOM 3949 C CG . TRP D 1 93 ? -23.829 -10.089 -5.637 1.00 29.84 ? 313 TRP D CG 1 ATOM 3950 C CD1 . TRP D 1 93 ? -24.573 -10.512 -6.731 1.00 28.07 ? 313 TRP D CD1 1 ATOM 3951 C CD2 . TRP D 1 93 ? -24.601 -10.515 -4.459 1.00 28.31 ? 313 TRP D CD2 1 ATOM 3952 N NE1 . TRP D 1 93 ? -25.734 -11.116 -6.327 1.00 30.73 ? 313 TRP D NE1 1 ATOM 3953 C CE2 . TRP D 1 93 ? -25.815 -11.153 -4.977 1.00 29.38 ? 313 TRP D CE2 1 ATOM 3954 C CE3 . TRP D 1 93 ? -24.422 -10.420 -3.081 1.00 26.70 ? 313 TRP D CE3 1 ATOM 3955 C CZ2 . TRP D 1 93 ? -26.790 -11.675 -4.135 1.00 29.63 ? 313 TRP D CZ2 1 ATOM 3956 C CZ3 . TRP D 1 93 ? -25.420 -10.931 -2.242 1.00 25.60 ? 313 TRP D CZ3 1 ATOM 3957 C CH2 . TRP D 1 93 ? -26.572 -11.542 -2.754 1.00 26.53 ? 313 TRP D CH2 1 ATOM 3958 N N . LEU D 1 94 ? -20.997 -11.197 -7.730 1.00 33.92 ? 314 LEU D N 1 ATOM 3959 C CA . LEU D 1 94 ? -21.071 -12.120 -8.861 1.00 40.32 ? 314 LEU D CA 1 ATOM 3960 C C . LEU D 1 94 ? -20.119 -13.321 -8.708 1.00 43.17 ? 314 LEU D C 1 ATOM 3961 O O . LEU D 1 94 ? -20.426 -14.416 -9.177 1.00 36.53 ? 314 LEU D O 1 ATOM 3962 C CB . LEU D 1 94 ? -20.880 -11.379 -10.187 1.00 37.37 ? 314 LEU D CB 1 ATOM 3963 C CG . LEU D 1 94 ? -22.007 -10.374 -10.471 1.00 45.50 ? 314 LEU D CG 1 ATOM 3964 C CD1 . LEU D 1 94 ? -21.595 -9.359 -11.525 1.00 49.29 ? 314 LEU D CD1 1 ATOM 3965 C CD2 . LEU D 1 94 ? -23.311 -11.071 -10.852 1.00 47.81 ? 314 LEU D CD2 1 ATOM 3966 N N . ASN D 1 95 ? -18.995 -13.129 -8.012 1.00 47.08 ? 315 ASN D N 1 ATOM 3967 C CA . ASN D 1 95 ? -18.123 -14.259 -7.647 1.00 47.92 ? 315 ASN D CA 1 ATOM 3968 C C . ASN D 1 95 ? -18.770 -15.149 -6.589 1.00 50.84 ? 315 ASN D C 1 ATOM 3969 O O . ASN D 1 95 ? -18.332 -16.276 -6.357 1.00 51.44 ? 315 ASN D O 1 ATOM 3970 C CB . ASN D 1 95 ? -16.752 -13.783 -7.160 1.00 43.41 ? 315 ASN D CB 1 ATOM 3971 C CG . ASN D 1 95 ? -15.889 -13.240 -8.281 1.00 48.77 ? 315 ASN D CG 1 ATOM 3972 O OD1 . ASN D 1 95 ? -16.169 -13.450 -9.464 1.00 49.70 ? 315 ASN D OD1 1 ATOM 3973 N ND2 . ASN D 1 95 ? -14.832 -12.530 -7.912 1.00 47.61 ? 315 ASN D ND2 1 ATOM 3974 N N . GLY D 1 96 ? -19.814 -14.633 -5.950 1.00 41.46 ? 316 GLY D N 1 ATOM 3975 C CA . GLY D 1 96 ? -20.581 -15.424 -5.013 1.00 49.69 ? 316 GLY D CA 1 ATOM 3976 C C . GLY D 1 96 ? -20.062 -15.321 -3.599 1.00 45.51 ? 316 GLY D C 1 ATOM 3977 O O . GLY D 1 96 ? -20.212 -16.254 -2.816 1.00 49.19 ? 316 GLY D O 1 ATOM 3978 N N . LYS D 1 97 ? -19.455 -14.186 -3.265 1.00 39.61 ? 317 LYS D N 1 ATOM 3979 C CA . LYS D 1 97 ? -19.061 -13.928 -1.882 1.00 38.57 ? 317 LYS D CA 1 ATOM 3980 C C . LYS D 1 97 ? -20.279 -13.904 -0.947 1.00 46.01 ? 317 LYS D C 1 ATOM 3981 O O . LYS D 1 97 ? -21.378 -13.484 -1.333 1.00 41.96 ? 317 LYS D O 1 ATOM 3982 C CB . LYS D 1 97 ? -18.251 -12.637 -1.762 1.00 40.12 ? 317 LYS D CB 1 ATOM 3983 C CG . LYS D 1 97 ? -16.861 -12.718 -2.389 1.00 42.48 ? 317 LYS D CG 1 ATOM 3984 C CD . LYS D 1 97 ? -15.855 -11.848 -1.646 1.00 44.40 ? 317 LYS D CD 1 ATOM 3985 C CE . LYS D 1 97 ? -14.578 -11.611 -2.453 1.00 50.62 ? 317 LYS D CE 1 ATOM 3986 N NZ . LYS D 1 97 ? -13.897 -12.854 -2.933 1.00 45.51 ? 317 LYS D NZ 1 ATOM 3987 N N . GLU D 1 98 ? -20.081 -14.381 0.277 1.00 46.66 ? 318 GLU D N 1 ATOM 3988 C CA . GLU D 1 98 ? -21.171 -14.493 1.232 1.00 40.36 ? 318 GLU D CA 1 ATOM 3989 C C . GLU D 1 98 ? -21.106 -13.339 2.188 1.00 32.52 ? 318 GLU D C 1 ATOM 3990 O O . GLU D 1 98 ? -20.040 -13.027 2.718 1.00 35.55 ? 318 GLU D O 1 ATOM 3991 C CB . GLU D 1 98 ? -21.102 -15.815 1.995 1.00 42.80 ? 318 GLU D CB 1 ATOM 3992 C CG . GLU D 1 98 ? -21.441 -17.029 1.148 1.00 47.12 ? 318 GLU D CG 1 ATOM 3993 C CD . GLU D 1 98 ? -21.729 -18.266 1.973 1.00 58.58 ? 318 GLU D CD 1 ATOM 3994 O OE1 . GLU D 1 98 ? -22.366 -18.154 3.049 1.00 58.66 ? 318 GLU D OE1 1 ATOM 3995 O OE2 . GLU D 1 98 ? -21.320 -19.358 1.532 1.00 60.56 ? 318 GLU D OE2 1 ATOM 3996 N N . TYR D 1 99 ? -22.250 -12.700 2.400 1.00 32.01 ? 319 TYR D N 1 ATOM 3997 C CA . TYR D 1 99 ? -22.326 -11.554 3.291 1.00 32.70 ? 319 TYR D CA 1 ATOM 3998 C C . TYR D 1 99 ? -23.099 -11.903 4.538 1.00 37.10 ? 319 TYR D C 1 ATOM 3999 O O . TYR D 1 99 ? -24.240 -12.384 4.455 1.00 43.39 ? 319 TYR D O 1 ATOM 4000 C CB . TYR D 1 99 ? -22.959 -10.368 2.578 1.00 29.70 ? 319 TYR D CB 1 ATOM 4001 C CG . TYR D 1 99 ? -22.125 -9.893 1.427 1.00 33.31 ? 319 TYR D CG 1 ATOM 4002 C CD1 . TYR D 1 99 ? -22.232 -10.496 0.170 1.00 29.48 ? 319 TYR D CD1 1 ATOM 4003 C CD2 . TYR D 1 99 ? -21.194 -8.863 1.598 1.00 33.21 ? 319 TYR D CD2 1 ATOM 4004 C CE1 . TYR D 1 99 ? -21.451 -10.072 -0.885 1.00 36.04 ? 319 TYR D CE1 1 ATOM 4005 C CE2 . TYR D 1 99 ? -20.410 -8.431 0.542 1.00 34.47 ? 319 TYR D CE2 1 ATOM 4006 C CZ . TYR D 1 99 ? -20.542 -9.040 -0.690 1.00 34.75 ? 319 TYR D CZ 1 ATOM 4007 O OH . TYR D 1 99 ? -19.770 -8.618 -1.737 1.00 47.80 ? 319 TYR D OH 1 ATOM 4008 N N . LYS D 1 100 ? -22.463 -11.679 5.688 1.00 33.91 ? 320 LYS D N 1 ATOM 4009 C CA . LYS D 1 100 ? -23.073 -11.969 6.975 1.00 32.85 ? 320 LYS D CA 1 ATOM 4010 C C . LYS D 1 100 ? -23.348 -10.696 7.765 1.00 36.66 ? 320 LYS D C 1 ATOM 4011 O O . LYS D 1 100 ? -22.454 -9.894 7.987 1.00 37.43 ? 320 LYS D O 1 ATOM 4012 C CB . LYS D 1 100 ? -22.213 -12.925 7.806 1.00 33.06 ? 320 LYS D CB 1 ATOM 4013 C CG . LYS D 1 100 ? -22.787 -13.190 9.197 1.00 36.63 ? 320 LYS D CG 1 ATOM 4014 C CD . LYS D 1 100 ? -21.732 -13.634 10.199 1.00 41.61 ? 320 LYS D CD 1 ATOM 4015 C CE . LYS D 1 100 ? -21.670 -15.146 10.342 1.00 44.09 ? 320 LYS D CE 1 ATOM 4016 N NZ . LYS D 1 100 ? -20.552 -15.556 11.239 1.00 38.87 ? 320 LYS D NZ 1 ATOM 4017 N N . CYS D 1 101 ? -24.602 -10.525 8.169 1.00 35.54 ? 321 CYS D N 1 ATOM 4018 C CA . CYS D 1 101 ? -24.991 -9.489 9.104 1.00 33.42 ? 321 CYS D CA 1 ATOM 4019 C C . CYS D 1 101 ? -25.182 -10.115 10.488 1.00 32.49 ? 321 CYS D C 1 ATOM 4020 O O . CYS D 1 101 ? -25.969 -11.049 10.634 1.00 32.56 ? 321 CYS D O 1 ATOM 4021 C CB . CYS D 1 101 ? -26.304 -8.843 8.642 1.00 36.30 ? 321 CYS D CB 1 ATOM 4022 S SG . CYS D 1 101 ? -26.844 -7.529 9.747 1.00 41.34 ? 321 CYS D SG 1 ATOM 4023 N N . LYS D 1 102 ? -24.471 -9.594 11.492 1.00 34.37 ? 322 LYS D N 1 ATOM 4024 C CA . LYS D 1 102 ? -24.624 -10.018 12.887 1.00 30.53 ? 322 LYS D CA 1 ATOM 4025 C C . LYS D 1 102 ? -25.247 -8.878 13.685 1.00 35.23 ? 322 LYS D C 1 ATOM 4026 O O . LYS D 1 102 ? -24.723 -7.769 13.708 1.00 35.44 ? 322 LYS D O 1 ATOM 4027 C CB . LYS D 1 102 ? -23.272 -10.424 13.514 1.00 29.36 ? 322 LYS D CB 1 ATOM 4028 C CG . LYS D 1 102 ? -23.391 -10.948 14.956 1.00 33.98 ? 322 LYS D CG 1 ATOM 4029 C CD . LYS D 1 102 ? -22.079 -10.909 15.748 1.00 31.65 ? 322 LYS D CD 1 ATOM 4030 N N . VAL D 1 103 ? -26.366 -9.161 14.345 1.00 32.87 ? 323 VAL D N 1 ATOM 4031 C CA . VAL D 1 103 ? -27.139 -8.128 15.010 1.00 30.13 ? 323 VAL D CA 1 ATOM 4032 C C . VAL D 1 103 ? -27.174 -8.375 16.530 1.00 33.95 ? 323 VAL D C 1 ATOM 4033 O O . VAL D 1 103 ? -27.562 -9.461 16.975 1.00 31.94 ? 323 VAL D O 1 ATOM 4034 C CB . VAL D 1 103 ? -28.576 -8.048 14.431 1.00 32.99 ? 323 VAL D CB 1 ATOM 4035 C CG1 . VAL D 1 103 ? -29.442 -7.126 15.263 1.00 27.67 ? 323 VAL D CG1 1 ATOM 4036 C CG2 . VAL D 1 103 ? -28.581 -7.601 12.955 1.00 27.89 ? 323 VAL D CG2 1 ATOM 4037 N N . SER D 1 104 ? -26.782 -7.358 17.301 1.00 32.28 ? 324 SER D N 1 ATOM 4038 C CA . SER D 1 104 ? -26.769 -7.403 18.774 1.00 37.23 ? 324 SER D CA 1 ATOM 4039 C C . SER D 1 104 ? -27.663 -6.337 19.388 1.00 38.21 ? 324 SER D C 1 ATOM 4040 O O . SER D 1 104 ? -27.673 -5.176 18.954 1.00 35.66 ? 324 SER D O 1 ATOM 4041 C CB . SER D 1 104 ? -25.352 -7.226 19.332 1.00 33.61 ? 324 SER D CB 1 ATOM 4042 O OG . SER D 1 104 ? -24.472 -8.185 18.781 1.00 40.26 ? 324 SER D OG 1 ATOM 4043 N N . ASN D 1 105 ? -28.393 -6.743 20.423 1.00 37.98 ? 325 ASN D N 1 ATOM 4044 C CA . ASN D 1 105 ? -29.362 -5.893 21.097 1.00 38.49 ? 325 ASN D CA 1 ATOM 4045 C C . ASN D 1 105 ? -29.663 -6.493 22.466 1.00 38.32 ? 325 ASN D C 1 ATOM 4046 O O . ASN D 1 105 ? -29.753 -7.715 22.615 1.00 38.38 ? 325 ASN D O 1 ATOM 4047 C CB . ASN D 1 105 ? -30.636 -5.770 20.247 1.00 36.55 ? 325 ASN D CB 1 ATOM 4048 C CG . ASN D 1 105 ? -31.750 -5.005 20.944 1.00 37.41 ? 325 ASN D CG 1 ATOM 4049 O OD1 . ASN D 1 105 ? -32.621 -5.604 21.570 1.00 41.35 ? 325 ASN D OD1 1 ATOM 4050 N ND2 . ASN D 1 105 ? -31.743 -3.684 20.816 1.00 38.69 ? 325 ASN D ND2 1 ATOM 4051 N N . LYS D 1 106 ? -29.824 -5.631 23.460 1.00 34.64 ? 326 LYS D N 1 ATOM 4052 C CA . LYS D 1 106 ? -29.991 -6.085 24.837 1.00 41.14 ? 326 LYS D CA 1 ATOM 4053 C C . LYS D 1 106 ? -31.196 -7.013 25.042 1.00 44.71 ? 326 LYS D C 1 ATOM 4054 O O . LYS D 1 106 ? -31.202 -7.819 25.969 1.00 45.99 ? 326 LYS D O 1 ATOM 4055 C CB . LYS D 1 106 ? -30.063 -4.887 25.781 1.00 34.44 ? 326 LYS D CB 1 ATOM 4056 C CG . LYS D 1 106 ? -28.737 -4.538 26.429 1.00 49.19 ? 326 LYS D CG 1 ATOM 4057 C CD . LYS D 1 106 ? -28.966 -3.818 27.755 1.00 53.44 ? 326 LYS D CD 1 ATOM 4058 C CE . LYS D 1 106 ? -27.654 -3.334 28.352 1.00 59.61 ? 326 LYS D CE 1 ATOM 4059 N NZ . LYS D 1 106 ? -27.868 -2.273 29.374 1.00 48.59 ? 326 LYS D NZ 1 ATOM 4060 N N . ALA D 1 107 ? -32.202 -6.915 24.171 1.00 39.99 ? 327 ALA D N 1 ATOM 4061 C CA . ALA D 1 107 ? -33.383 -7.777 24.288 1.00 42.32 ? 327 ALA D CA 1 ATOM 4062 C C . ALA D 1 107 ? -33.190 -9.162 23.666 1.00 37.58 ? 327 ALA D C 1 ATOM 4063 O O . ALA D 1 107 ? -34.087 -10.000 23.724 1.00 38.82 ? 327 ALA D O 1 ATOM 4064 C CB . ALA D 1 107 ? -34.619 -7.094 23.726 1.00 33.29 ? 327 ALA D CB 1 ATOM 4065 N N . LEU D 1 108 ? -32.019 -9.398 23.082 1.00 39.95 ? 328 LEU D N 1 ATOM 4066 C CA . LEU D 1 108 ? -31.684 -10.695 22.497 1.00 42.58 ? 328 LEU D CA 1 ATOM 4067 C C . LEU D 1 108 ? -30.826 -11.516 23.459 1.00 47.43 ? 328 LEU D C 1 ATOM 4068 O O . LEU D 1 108 ? -29.859 -10.988 24.014 1.00 46.00 ? 328 LEU D O 1 ATOM 4069 C CB . LEU D 1 108 ? -30.935 -10.495 21.175 1.00 42.50 ? 328 LEU D CB 1 ATOM 4070 C CG . LEU D 1 108 ? -31.583 -10.731 19.800 1.00 44.40 ? 328 LEU D CG 1 ATOM 4071 C CD1 . LEU D 1 108 ? -33.106 -10.724 19.798 1.00 44.87 ? 328 LEU D CD1 1 ATOM 4072 C CD2 . LEU D 1 108 ? -31.040 -9.733 18.792 1.00 39.11 ? 328 LEU D CD2 1 ATOM 4073 N N . PRO D 1 109 ? -31.178 -12.807 23.665 1.00 58.14 ? 329 PRO D N 1 ATOM 4074 C CA . PRO D 1 109 ? -30.352 -13.727 24.469 1.00 58.83 ? 329 PRO D CA 1 ATOM 4075 C C . PRO D 1 109 ? -28.949 -13.833 23.885 1.00 60.96 ? 329 PRO D C 1 ATOM 4076 O O . PRO D 1 109 ? -27.953 -13.698 24.608 1.00 48.84 ? 329 PRO D O 1 ATOM 4077 C CB . PRO D 1 109 ? -31.071 -15.074 24.321 1.00 50.58 ? 329 PRO D CB 1 ATOM 4078 C CG . PRO D 1 109 ? -32.481 -14.721 23.991 1.00 56.45 ? 329 PRO D CG 1 ATOM 4079 C CD . PRO D 1 109 ? -32.408 -13.460 23.175 1.00 52.27 ? 329 PRO D CD 1 ATOM 4080 N N . ALA D 1 110 ? -28.900 -14.054 22.572 1.00 53.40 ? 330 ALA D N 1 ATOM 4081 C CA . ALA D 1 110 ? -27.667 -14.180 21.822 1.00 47.68 ? 330 ALA D CA 1 ATOM 4082 C C . ALA D 1 110 ? -27.816 -13.411 20.516 1.00 46.73 ? 330 ALA D C 1 ATOM 4083 O O . ALA D 1 110 ? -28.890 -13.443 19.910 1.00 44.30 ? 330 ALA D O 1 ATOM 4084 C CB . ALA D 1 110 ? -27.387 -15.647 21.532 1.00 43.38 ? 330 ALA D CB 1 ATOM 4085 N N . PRO D 1 111 ? -26.741 -12.727 20.073 1.00 42.19 ? 331 PRO D N 1 ATOM 4086 C CA . PRO D 1 111 ? -26.738 -12.008 18.794 1.00 42.04 ? 331 PRO D CA 1 ATOM 4087 C C . PRO D 1 111 ? -27.271 -12.860 17.637 1.00 39.64 ? 331 PRO D C 1 ATOM 4088 O O . PRO D 1 111 ? -27.052 -14.065 17.605 1.00 42.10 ? 331 PRO D O 1 ATOM 4089 C CB . PRO D 1 111 ? -25.256 -11.699 18.578 1.00 44.10 ? 331 PRO D CB 1 ATOM 4090 C CG . PRO D 1 111 ? -24.710 -11.568 19.963 1.00 43.51 ? 331 PRO D CG 1 ATOM 4091 C CD . PRO D 1 111 ? -25.455 -12.581 20.787 1.00 40.38 ? 331 PRO D CD 1 ATOM 4092 N N . ILE D 1 112 ? -27.986 -12.242 16.708 1.00 39.24 ? 332 ILE D N 1 ATOM 4093 C CA . ILE D 1 112 ? -28.519 -12.984 15.567 1.00 35.78 ? 332 ILE D CA 1 ATOM 4094 C C . ILE D 1 112 ? -27.688 -12.743 14.313 1.00 38.50 ? 332 ILE D C 1 ATOM 4095 O O . ILE D 1 112 ? -27.341 -11.608 13.992 1.00 38.38 ? 332 ILE D O 1 ATOM 4096 C CB . ILE D 1 112 ? -30.008 -12.673 15.304 1.00 37.41 ? 332 ILE D CB 1 ATOM 4097 C CG1 . ILE D 1 112 ? -30.869 -13.128 16.495 1.00 40.19 ? 332 ILE D CG1 1 ATOM 4098 C CG2 . ILE D 1 112 ? -30.477 -13.346 14.020 1.00 32.98 ? 332 ILE D CG2 1 ATOM 4099 C CD1 . ILE D 1 112 ? -32.280 -12.563 16.513 1.00 43.92 ? 332 ILE D CD1 1 ATOM 4100 N N . GLU D 1 113 ? -27.381 -13.834 13.618 1.00 38.68 ? 333 GLU D N 1 ATOM 4101 C CA . GLU D 1 113 ? -26.576 -13.816 12.419 1.00 39.00 ? 333 GLU D CA 1 ATOM 4102 C C . GLU D 1 113 ? -27.413 -14.238 11.228 1.00 39.28 ? 333 GLU D C 1 ATOM 4103 O O . GLU D 1 113 ? -28.147 -15.221 11.287 1.00 43.18 ? 333 GLU D O 1 ATOM 4104 C CB . GLU D 1 113 ? -25.400 -14.782 12.555 1.00 46.00 ? 333 GLU D CB 1 ATOM 4105 C CG . GLU D 1 113 ? -24.299 -14.342 13.509 1.00 49.80 ? 333 GLU D CG 1 ATOM 4106 C CD . GLU D 1 113 ? -23.162 -15.348 13.600 1.00 50.83 ? 333 GLU D CD 1 ATOM 4107 O OE1 . GLU D 1 113 ? -21.989 -14.926 13.716 1.00 55.72 ? 333 GLU D OE1 1 ATOM 4108 O OE2 . GLU D 1 113 ? -23.435 -16.565 13.551 1.00 63.35 ? 333 GLU D OE2 1 ATOM 4109 N N . LYS D 1 114 ? -27.301 -13.484 10.144 1.00 32.23 ? 334 LYS D N 1 ATOM 4110 C CA . LYS D 1 114 ? -27.896 -13.881 8.886 1.00 30.33 ? 334 LYS D CA 1 ATOM 4111 C C . LYS D 1 114 ? -26.839 -13.750 7.820 1.00 37.42 ? 334 LYS D C 1 ATOM 4112 O O . LYS D 1 114 ? -25.947 -12.905 7.912 1.00 46.71 ? 334 LYS D O 1 ATOM 4113 C CB . LYS D 1 114 ? -29.084 -12.981 8.521 1.00 29.41 ? 334 LYS D CB 1 ATOM 4114 C CG . LYS D 1 114 ? -30.306 -13.101 9.419 1.00 31.75 ? 334 LYS D CG 1 ATOM 4115 C CD . LYS D 1 114 ? -31.022 -14.433 9.275 1.00 31.25 ? 334 LYS D CD 1 ATOM 4116 C CE . LYS D 1 114 ? -32.251 -14.462 10.174 1.00 31.73 ? 334 LYS D CE 1 ATOM 4117 N NZ . LYS D 1 114 ? -33.153 -15.616 9.903 1.00 29.41 ? 334 LYS D NZ 1 ATOM 4118 N N . THR D 1 115 ? -26.959 -14.573 6.795 1.00 28.75 ? 335 THR D N 1 ATOM 4119 C CA . THR D 1 115 ? -26.020 -14.564 5.697 1.00 38.35 ? 335 THR D CA 1 ATOM 4120 C C . THR D 1 115 ? -26.830 -14.635 4.422 1.00 35.05 ? 335 THR D C 1 ATOM 4121 O O . THR D 1 115 ? -27.917 -15.200 4.420 1.00 37.95 ? 335 THR D O 1 ATOM 4122 C CB . THR D 1 115 ? -25.070 -15.781 5.790 1.00 38.31 ? 335 THR D CB 1 ATOM 4123 O OG1 . THR D 1 115 ? -24.299 -15.677 6.993 1.00 38.92 ? 335 THR D OG1 1 ATOM 4124 C CG2 . THR D 1 115 ? -24.122 -15.845 4.599 1.00 37.32 ? 335 THR D CG2 1 ATOM 4125 N N . ILE D 1 116 ? -26.321 -14.022 3.357 1.00 37.99 ? 336 ILE D N 1 ATOM 4126 C CA . ILE D 1 116 ? -26.851 -14.232 2.010 1.00 33.97 ? 336 ILE D CA 1 ATOM 4127 C C . ILE D 1 116 ? -25.750 -14.081 0.986 1.00 35.64 ? 336 ILE D C 1 ATOM 4128 O O . ILE D 1 116 ? -24.683 -13.524 1.269 1.00 26.97 ? 336 ILE D O 1 ATOM 4129 C CB . ILE D 1 116 ? -27.950 -13.234 1.597 1.00 45.17 ? 336 ILE D CB 1 ATOM 4130 C CG1 . ILE D 1 116 ? -27.546 -11.811 1.973 1.00 43.69 ? 336 ILE D CG1 1 ATOM 4131 C CG2 . ILE D 1 116 ? -29.314 -13.650 2.140 1.00 52.61 ? 336 ILE D CG2 1 ATOM 4132 C CD1 . ILE D 1 116 ? -27.892 -10.799 0.915 1.00 48.96 ? 336 ILE D CD1 1 ATOM 4133 N N . SER D 1 117 ? -26.044 -14.567 -0.217 1.00 29.82 ? 337 SER D N 1 ATOM 4134 C CA . SER D 1 117 ? -25.131 -14.504 -1.339 1.00 31.94 ? 337 SER D CA 1 ATOM 4135 C C . SER D 1 117 ? -25.913 -14.959 -2.564 1.00 34.32 ? 337 SER D C 1 ATOM 4136 O O . SER D 1 117 ? -27.038 -15.459 -2.445 1.00 35.71 ? 337 SER D O 1 ATOM 4137 C CB . SER D 1 117 ? -23.940 -15.452 -1.114 1.00 41.23 ? 337 SER D CB 1 ATOM 4138 O OG . SER D 1 117 ? -24.359 -16.812 -1.057 1.00 45.28 ? 337 SER D OG 1 ATOM 4139 N N . LYS D 1 118 ? -25.316 -14.796 -3.736 1.00 30.53 ? 338 LYS D N 1 ATOM 4140 C CA . LYS D 1 118 ? -25.925 -15.280 -4.959 1.00 33.12 ? 338 LYS D CA 1 ATOM 4141 C C . LYS D 1 118 ? -26.131 -16.794 -4.855 1.00 29.53 ? 338 LYS D C 1 ATOM 4142 O O . LYS D 1 118 ? -25.270 -17.509 -4.362 1.00 33.12 ? 338 LYS D O 1 ATOM 4143 C CB . LYS D 1 118 ? -25.011 -14.933 -6.135 1.00 35.53 ? 338 LYS D CB 1 ATOM 4144 C CG . LYS D 1 118 ? -25.597 -15.191 -7.517 1.00 41.95 ? 338 LYS D CG 1 ATOM 4145 C CD . LYS D 1 118 ? -24.555 -14.938 -8.607 1.00 36.75 ? 338 LYS D CD 1 ATOM 4146 C CE . LYS D 1 118 ? -23.469 -16.009 -8.601 1.00 40.39 ? 338 LYS D CE 1 ATOM 4147 N NZ . LYS D 1 118 ? -22.604 -15.949 -9.809 1.00 51.56 ? 338 LYS D NZ 1 ATOM 4148 N N . ALA D 1 119 ? -27.288 -17.272 -5.288 1.00 32.04 ? 339 ALA D N 1 ATOM 4149 C CA . ALA D 1 119 ? -27.501 -18.702 -5.497 1.00 35.68 ? 339 ALA D CA 1 ATOM 4150 C C . ALA D 1 119 ? -26.260 -19.378 -6.098 1.00 36.83 ? 339 ALA D C 1 ATOM 4151 O O . ALA D 1 119 ? -25.684 -18.881 -7.064 1.00 42.36 ? 339 ALA D O 1 ATOM 4152 C CB . ALA D 1 119 ? -28.704 -18.911 -6.402 1.00 37.26 ? 339 ALA D CB 1 ATOM 4153 N N . LYS D 1 120 ? -25.847 -20.505 -5.524 1.00 37.51 ? 340 LYS D N 1 ATOM 4154 C CA . LYS D 1 120 ? -24.672 -21.218 -6.021 1.00 36.02 ? 340 LYS D CA 1 ATOM 4155 C C . LYS D 1 120 ? -25.066 -22.113 -7.189 1.00 35.70 ? 340 LYS D C 1 ATOM 4156 O O . LYS D 1 120 ? -26.220 -22.546 -7.302 1.00 37.30 ? 340 LYS D O 1 ATOM 4157 C CB . LYS D 1 120 ? -23.977 -22.020 -4.907 1.00 35.52 ? 340 LYS D CB 1 ATOM 4158 C CG . LYS D 1 120 ? -23.269 -21.153 -3.874 1.00 40.23 ? 340 LYS D CG 1 ATOM 4159 C CD . LYS D 1 120 ? -22.772 -21.967 -2.688 1.00 42.93 ? 340 LYS D CD 1 ATOM 4160 N N . GLY D 1 121 ? -24.106 -22.374 -8.064 1.00 32.85 ? 341 GLY D N 1 ATOM 4161 C CA . GLY D 1 121 ? -24.376 -23.084 -9.311 1.00 35.47 ? 341 GLY D CA 1 ATOM 4162 C C . GLY D 1 121 ? -23.758 -22.369 -10.498 1.00 36.35 ? 341 GLY D C 1 ATOM 4163 O O . GLY D 1 121 ? -23.647 -21.139 -10.521 1.00 33.50 ? 341 GLY D O 1 ATOM 4164 N N . GLN D 1 122 ? -23.350 -23.147 -11.489 1.00 36.82 ? 342 GLN D N 1 ATOM 4165 C CA . GLN D 1 122 ? -22.701 -22.608 -12.666 1.00 39.66 ? 342 GLN D CA 1 ATOM 4166 C C . GLN D 1 122 ? -23.683 -21.755 -13.483 1.00 37.11 ? 342 GLN D C 1 ATOM 4167 O O . GLN D 1 122 ? -24.746 -22.230 -13.854 1.00 40.38 ? 342 GLN D O 1 ATOM 4168 C CB . GLN D 1 122 ? -22.121 -23.752 -13.495 1.00 35.88 ? 342 GLN D CB 1 ATOM 4169 C CG . GLN D 1 122 ? -21.684 -23.382 -14.902 1.00 37.48 ? 342 GLN D CG 1 ATOM 4170 C CD . GLN D 1 122 ? -21.459 -24.614 -15.752 1.00 55.64 ? 342 GLN D CD 1 ATOM 4171 O OE1 . GLN D 1 122 ? -21.115 -25.685 -15.227 1.00 51.08 ? 342 GLN D OE1 1 ATOM 4172 N NE2 . GLN D 1 122 ? -21.658 -24.479 -17.070 1.00 42.60 ? 342 GLN D NE2 1 ATOM 4173 N N . PRO D 1 123 ? -23.319 -20.494 -13.757 1.00 35.85 ? 343 PRO D N 1 ATOM 4174 C CA . PRO D 1 123 ? -24.149 -19.567 -14.530 1.00 35.40 ? 343 PRO D CA 1 ATOM 4175 C C . PRO D 1 123 ? -24.481 -20.072 -15.941 1.00 39.79 ? 343 PRO D C 1 ATOM 4176 O O . PRO D 1 123 ? -23.609 -20.588 -16.640 1.00 37.77 ? 343 PRO D O 1 ATOM 4177 C CB . PRO D 1 123 ? -23.279 -18.307 -14.595 1.00 36.76 ? 343 PRO D CB 1 ATOM 4178 C CG . PRO D 1 123 ? -22.468 -18.362 -13.337 1.00 39.25 ? 343 PRO D CG 1 ATOM 4179 C CD . PRO D 1 123 ? -22.116 -19.824 -13.222 1.00 38.40 ? 343 PRO D CD 1 ATOM 4180 N N . ARG D 1 124 ? -25.743 -19.945 -16.342 1.00 36.01 ? 344 ARG D N 1 ATOM 4181 C CA . ARG D 1 124 ? -26.166 -20.387 -17.671 1.00 34.35 ? 344 ARG D CA 1 ATOM 4182 C C . ARG D 1 124 ? -26.806 -19.237 -18.404 1.00 36.73 ? 344 ARG D C 1 ATOM 4183 O O . ARG D 1 124 ? -27.534 -18.433 -17.811 1.00 35.59 ? 344 ARG D O 1 ATOM 4184 C CB . ARG D 1 124 ? -27.145 -21.558 -17.592 1.00 33.77 ? 344 ARG D CB 1 ATOM 4185 C CG . ARG D 1 124 ? -26.503 -22.866 -17.194 1.00 32.02 ? 344 ARG D CG 1 ATOM 4186 C CD . ARG D 1 124 ? -27.517 -23.976 -17.020 1.00 36.85 ? 344 ARG D CD 1 ATOM 4187 N NE . ARG D 1 124 ? -28.185 -24.364 -18.262 1.00 43.24 ? 344 ARG D NE 1 ATOM 4188 C CZ . ARG D 1 124 ? -29.161 -25.268 -18.325 1.00 48.98 ? 344 ARG D CZ 1 ATOM 4189 N NH1 . ARG D 1 124 ? -29.574 -25.875 -17.215 1.00 42.99 ? 344 ARG D NH1 1 ATOM 4190 N NH2 . ARG D 1 124 ? -29.723 -25.572 -19.493 1.00 43.41 ? 344 ARG D NH2 1 ATOM 4191 N N . GLU D 1 125 ? -26.527 -19.166 -19.700 1.00 38.50 ? 345 GLU D N 1 ATOM 4192 C CA . GLU D 1 125 ? -26.972 -18.052 -20.519 1.00 36.75 ? 345 GLU D CA 1 ATOM 4193 C C . GLU D 1 125 ? -28.446 -18.168 -20.859 1.00 29.90 ? 345 GLU D C 1 ATOM 4194 O O . GLU D 1 125 ? -28.888 -19.222 -21.333 1.00 41.88 ? 345 GLU D O 1 ATOM 4195 C CB . GLU D 1 125 ? -26.137 -17.962 -21.805 1.00 39.92 ? 345 GLU D CB 1 ATOM 4196 C CG . GLU D 1 125 ? -26.401 -16.702 -22.615 1.00 43.27 ? 345 GLU D CG 1 ATOM 4197 C CD . GLU D 1 125 ? -25.611 -16.642 -23.906 1.00 45.62 ? 345 GLU D CD 1 ATOM 4198 O OE1 . GLU D 1 125 ? -25.200 -17.701 -24.419 1.00 50.05 ? 345 GLU D OE1 1 ATOM 4199 O OE2 . GLU D 1 125 ? -25.406 -15.524 -24.410 1.00 43.24 ? 345 GLU D OE2 1 ATOM 4200 N N . PRO D 1 126 ? -29.214 -17.086 -20.634 1.00 27.96 ? 346 PRO D N 1 ATOM 4201 C CA . PRO D 1 126 ? -30.601 -17.091 -21.088 1.00 36.63 ? 346 PRO D CA 1 ATOM 4202 C C . PRO D 1 126 ? -30.706 -17.033 -22.604 1.00 40.10 ? 346 PRO D C 1 ATOM 4203 O O . PRO D 1 126 ? -29.932 -16.317 -23.251 1.00 38.44 ? 346 PRO D O 1 ATOM 4204 C CB . PRO D 1 126 ? -31.175 -15.802 -20.492 1.00 34.36 ? 346 PRO D CB 1 ATOM 4205 C CG . PRO D 1 126 ? -30.004 -14.929 -20.244 1.00 32.95 ? 346 PRO D CG 1 ATOM 4206 C CD . PRO D 1 126 ? -28.893 -15.865 -19.870 1.00 31.86 ? 346 PRO D CD 1 ATOM 4207 N N . GLN D 1 127 ? -31.635 -17.811 -23.151 1.00 41.18 ? 347 GLN D N 1 ATOM 4208 C CA . GLN D 1 127 ? -32.091 -17.635 -24.523 1.00 40.86 ? 347 GLN D CA 1 ATOM 4209 C C . GLN D 1 127 ? -33.293 -16.698 -24.494 1.00 37.17 ? 347 GLN D C 1 ATOM 4210 O O . GLN D 1 127 ? -34.188 -16.868 -23.665 1.00 28.45 ? 347 GLN D O 1 ATOM 4211 C CB . GLN D 1 127 ? -32.482 -18.978 -25.139 1.00 45.64 ? 347 GLN D CB 1 ATOM 4212 C CG . GLN D 1 127 ? -31.366 -19.643 -25.928 1.00 56.70 ? 347 GLN D CG 1 ATOM 4213 C CD . GLN D 1 127 ? -30.325 -20.316 -25.051 1.00 58.91 ? 347 GLN D CD 1 ATOM 4214 O OE1 . GLN D 1 127 ? -29.129 -20.023 -25.150 1.00 54.74 ? 347 GLN D OE1 1 ATOM 4215 N NE2 . GLN D 1 127 ? -30.772 -21.233 -24.191 1.00 60.11 ? 347 GLN D NE2 1 ATOM 4216 N N . VAL D 1 128 ? -33.302 -15.705 -25.385 1.00 33.24 ? 348 VAL D N 1 ATOM 4217 C CA . VAL D 1 128 ? -34.337 -14.673 -25.397 1.00 27.64 ? 348 VAL D CA 1 ATOM 4218 C C . VAL D 1 128 ? -35.031 -14.641 -26.766 1.00 34.68 ? 348 VAL D C 1 ATOM 4219 O O . VAL D 1 128 ? -34.412 -14.343 -27.783 1.00 28.82 ? 348 VAL D O 1 ATOM 4220 C CB . VAL D 1 128 ? -33.756 -13.287 -25.043 1.00 33.71 ? 348 VAL D CB 1 ATOM 4221 C CG1 . VAL D 1 128 ? -34.841 -12.216 -25.078 1.00 36.52 ? 348 VAL D CG1 1 ATOM 4222 C CG2 . VAL D 1 128 ? -33.089 -13.305 -23.666 1.00 28.10 ? 348 VAL D CG2 1 ATOM 4223 N N . TYR D 1 129 ? -36.319 -14.968 -26.778 1.00 33.01 ? 349 TYR D N 1 ATOM 4224 C CA . TYR D 1 129 ? -37.100 -14.947 -27.999 1.00 37.83 ? 349 TYR D CA 1 ATOM 4225 C C . TYR D 1 129 ? -38.281 -14.008 -27.849 1.00 38.82 ? 349 TYR D C 1 ATOM 4226 O O . TYR D 1 129 ? -38.806 -13.823 -26.747 1.00 40.85 ? 349 TYR D O 1 ATOM 4227 C CB . TYR D 1 129 ? -37.598 -16.347 -28.344 1.00 33.61 ? 349 TYR D CB 1 ATOM 4228 C CG . TYR D 1 129 ? -36.529 -17.399 -28.264 1.00 41.01 ? 349 TYR D CG 1 ATOM 4229 C CD1 . TYR D 1 129 ? -35.441 -17.389 -29.145 1.00 47.08 ? 349 TYR D CD1 1 ATOM 4230 C CD2 . TYR D 1 129 ? -36.597 -18.412 -27.307 1.00 42.55 ? 349 TYR D CD2 1 ATOM 4231 C CE1 . TYR D 1 129 ? -34.448 -18.358 -29.073 1.00 47.32 ? 349 TYR D CE1 1 ATOM 4232 C CE2 . TYR D 1 129 ? -35.610 -19.386 -27.228 1.00 50.07 ? 349 TYR D CE2 1 ATOM 4233 C CZ . TYR D 1 129 ? -34.540 -19.357 -28.113 1.00 48.27 ? 349 TYR D CZ 1 ATOM 4234 O OH . TYR D 1 129 ? -33.565 -20.325 -28.035 1.00 50.28 ? 349 TYR D OH 1 ATOM 4235 N N . THR D 1 130 ? -38.687 -13.403 -28.961 1.00 35.44 ? 350 THR D N 1 ATOM 4236 C CA . THR D 1 130 ? -39.863 -12.554 -28.968 1.00 34.54 ? 350 THR D CA 1 ATOM 4237 C C . THR D 1 130 ? -40.960 -13.210 -29.772 1.00 34.85 ? 350 THR D C 1 ATOM 4238 O O . THR D 1 130 ? -40.700 -13.822 -30.812 1.00 45.01 ? 350 THR D O 1 ATOM 4239 C CB . THR D 1 130 ? -39.574 -11.146 -29.512 1.00 34.32 ? 350 THR D CB 1 ATOM 4240 O OG1 . THR D 1 130 ? -38.884 -11.250 -30.758 1.00 38.27 ? 350 THR D OG1 1 ATOM 4241 C CG2 . THR D 1 130 ? -38.711 -10.379 -28.546 1.00 31.10 ? 350 THR D CG2 1 ATOM 4242 N N . LEU D 1 131 ? -42.187 -13.075 -29.280 1.00 32.82 ? 351 LEU D N 1 ATOM 4243 C CA . LEU D 1 131 ? -43.353 -13.647 -29.931 1.00 38.25 ? 351 LEU D CA 1 ATOM 4244 C C . LEU D 1 131 ? -44.383 -12.563 -30.236 1.00 37.55 ? 351 LEU D C 1 ATOM 4245 O O . LEU D 1 131 ? -44.755 -11.774 -29.347 1.00 30.33 ? 351 LEU D O 1 ATOM 4246 C CB . LEU D 1 131 ? -43.965 -14.768 -29.078 1.00 38.86 ? 351 LEU D CB 1 ATOM 4247 C CG . LEU D 1 131 ? -43.050 -15.925 -28.669 1.00 45.17 ? 351 LEU D CG 1 ATOM 4248 C CD1 . LEU D 1 131 ? -43.760 -16.840 -27.684 1.00 45.05 ? 351 LEU D CD1 1 ATOM 4249 C CD2 . LEU D 1 131 ? -42.563 -16.711 -29.877 1.00 53.82 ? 351 LEU D CD2 1 ATOM 4250 N N . PRO D 1 132 ? -44.825 -12.505 -31.508 1.00 32.46 ? 352 PRO D N 1 ATOM 4251 C CA . PRO D 1 132 ? -45.901 -11.612 -31.924 1.00 31.93 ? 352 PRO D CA 1 ATOM 4252 C C . PRO D 1 132 ? -47.231 -12.028 -31.280 1.00 27.29 ? 352 PRO D C 1 ATOM 4253 O O . PRO D 1 132 ? -47.327 -13.121 -30.709 1.00 26.94 ? 352 PRO D O 1 ATOM 4254 C CB . PRO D 1 132 ? -45.956 -11.812 -33.458 1.00 30.07 ? 352 PRO D CB 1 ATOM 4255 C CG . PRO D 1 132 ? -45.312 -13.127 -33.704 1.00 29.04 ? 352 PRO D CG 1 ATOM 4256 C CD . PRO D 1 132 ? -44.240 -13.225 -32.656 1.00 34.51 ? 352 PRO D CD 1 ATOM 4257 N N . PRO D 1 133 ? -48.250 -11.160 -31.366 1.00 26.78 ? 353 PRO D N 1 ATOM 4258 C CA . PRO D 1 133 ? -49.588 -11.515 -30.893 1.00 28.80 ? 353 PRO D CA 1 ATOM 4259 C C . PRO D 1 133 ? -50.210 -12.607 -31.766 1.00 40.99 ? 353 PRO D C 1 ATOM 4260 O O . PRO D 1 133 ? -50.003 -12.620 -32.981 1.00 30.26 ? 353 PRO D O 1 ATOM 4261 C CB . PRO D 1 133 ? -50.377 -10.218 -31.067 1.00 26.00 ? 353 PRO D CB 1 ATOM 4262 C CG . PRO D 1 133 ? -49.364 -9.137 -31.271 1.00 24.01 ? 353 PRO D CG 1 ATOM 4263 C CD . PRO D 1 133 ? -48.205 -9.801 -31.935 1.00 26.14 ? 353 PRO D CD 1 ATOM 4264 N N . SER D 1 134 ? -50.948 -13.525 -31.150 1.00 42.74 ? 354 SER D N 1 ATOM 4265 C CA . SER D 1 134 ? -51.750 -14.481 -31.914 1.00 48.46 ? 354 SER D CA 1 ATOM 4266 C C . SER D 1 134 ? -52.657 -13.712 -32.873 1.00 51.35 ? 354 SER D C 1 ATOM 4267 O O . SER D 1 134 ? -53.227 -12.684 -32.489 1.00 47.99 ? 354 SER D O 1 ATOM 4268 C CB . SER D 1 134 ? -52.600 -15.331 -30.967 1.00 54.59 ? 354 SER D CB 1 ATOM 4269 O OG . SER D 1 134 ? -53.499 -16.169 -31.670 1.00 56.44 ? 354 SER D OG 1 ATOM 4270 N N . ARG D 1 135 ? -52.778 -14.190 -34.115 1.00 42.06 ? 355 ARG D N 1 ATOM 4271 C CA . ARG D 1 135 ? -53.718 -13.590 -35.071 1.00 44.10 ? 355 ARG D CA 1 ATOM 4272 C C . ARG D 1 135 ? -55.117 -13.455 -34.454 1.00 42.19 ? 355 ARG D C 1 ATOM 4273 O O . ARG D 1 135 ? -55.794 -12.449 -34.665 1.00 45.56 ? 355 ARG D O 1 ATOM 4274 C CB . ARG D 1 135 ? -53.766 -14.380 -36.391 1.00 51.35 ? 355 ARG D CB 1 ATOM 4275 N N . GLU D 1 136 ? -55.526 -14.450 -33.666 1.00 46.58 ? 356 GLU D N 1 ATOM 4276 C CA . GLU D 1 136 ? -56.772 -14.377 -32.887 1.00 51.49 ? 356 GLU D CA 1 ATOM 4277 C C . GLU D 1 136 ? -56.871 -13.145 -31.972 1.00 53.76 ? 356 GLU D C 1 ATOM 4278 O O . GLU D 1 136 ? -57.955 -12.595 -31.792 1.00 54.06 ? 356 GLU D O 1 ATOM 4279 C CB . GLU D 1 136 ? -56.960 -15.637 -32.042 1.00 60.04 ? 356 GLU D CB 1 ATOM 4280 C CG . GLU D 1 136 ? -57.335 -16.881 -32.829 1.00 65.04 ? 356 GLU D CG 1 ATOM 4281 C CD . GLU D 1 136 ? -58.088 -17.901 -31.991 1.00 74.37 ? 356 GLU D CD 1 ATOM 4282 O OE1 . GLU D 1 136 ? -57.960 -17.890 -30.743 1.00 80.58 ? 356 GLU D OE1 1 ATOM 4283 O OE2 . GLU D 1 136 ? -58.819 -18.720 -32.586 1.00 71.28 ? 356 GLU D OE2 1 ATOM 4284 N N . GLU D 1 137 ? -55.750 -12.722 -31.387 1.00 50.40 ? 357 GLU D N 1 ATOM 4285 C CA . GLU D 1 137 ? -55.738 -11.513 -30.550 1.00 44.76 ? 357 GLU D CA 1 ATOM 4286 C C . GLU D 1 137 ? -55.788 -10.235 -31.394 1.00 46.90 ? 357 GLU D C 1 ATOM 4287 O O . GLU D 1 137 ? -56.082 -9.157 -30.873 1.00 44.45 ? 357 GLU D O 1 ATOM 4288 C CB . GLU D 1 137 ? -54.525 -11.485 -29.597 1.00 43.76 ? 357 GLU D CB 1 ATOM 4289 C CG . GLU D 1 137 ? -54.732 -10.586 -28.373 1.00 40.46 ? 357 GLU D CG 1 ATOM 4290 C CD . GLU D 1 137 ? -53.489 -10.388 -27.508 1.00 44.83 ? 357 GLU D CD 1 ATOM 4291 O OE1 . GLU D 1 137 ? -52.344 -10.503 -28.010 1.00 39.21 ? 357 GLU D OE1 1 ATOM 4292 O OE2 . GLU D 1 137 ? -53.665 -10.093 -26.301 1.00 44.24 ? 357 GLU D OE2 1 ATOM 4293 N N . MET D 1 138 ? -55.526 -10.356 -32.696 1.00 53.83 ? 358 MET D N 1 ATOM 4294 C CA . MET D 1 138 ? -55.447 -9.179 -33.574 1.00 50.27 ? 358 MET D CA 1 ATOM 4295 C C . MET D 1 138 ? -56.793 -8.499 -33.788 1.00 46.65 ? 358 MET D C 1 ATOM 4296 O O . MET D 1 138 ? -56.872 -7.453 -34.429 1.00 49.07 ? 358 MET D O 1 ATOM 4297 C CB . MET D 1 138 ? -54.789 -9.522 -34.915 1.00 57.54 ? 358 MET D CB 1 ATOM 4298 C CG . MET D 1 138 ? -53.274 -9.638 -34.851 1.00 54.42 ? 358 MET D CG 1 ATOM 4299 S SD . MET D 1 138 ? -52.483 -8.177 -34.146 1.00 52.87 ? 358 MET D SD 1 ATOM 4300 C CE . MET D 1 138 ? -52.763 -6.934 -35.402 1.00 55.32 ? 358 MET D CE 1 ATOM 4301 N N . THR D 1 139 ? -57.841 -9.098 -33.229 1.00 52.03 ? 359 THR D N 1 ATOM 4302 C CA . THR D 1 139 ? -59.185 -8.539 -33.272 1.00 54.48 ? 359 THR D CA 1 ATOM 4303 C C . THR D 1 139 ? -59.486 -7.602 -32.083 1.00 59.86 ? 359 THR D C 1 ATOM 4304 O O . THR D 1 139 ? -60.424 -6.805 -32.145 1.00 61.98 ? 359 THR D O 1 ATOM 4305 C CB . THR D 1 139 ? -60.248 -9.662 -33.384 1.00 64.11 ? 359 THR D CB 1 ATOM 4306 O OG1 . THR D 1 139 ? -61.536 -9.082 -33.611 1.00 84.17 ? 359 THR D OG1 1 ATOM 4307 C CG2 . THR D 1 139 ? -60.295 -10.535 -32.117 1.00 57.75 ? 359 THR D CG2 1 ATOM 4308 N N . LYS D 1 140 ? -58.685 -7.691 -31.018 1.00 50.13 ? 360 LYS D N 1 ATOM 4309 C CA . LYS D 1 140 ? -58.894 -6.889 -29.794 1.00 44.17 ? 360 LYS D CA 1 ATOM 4310 C C . LYS D 1 140 ? -58.247 -5.489 -29.850 1.00 43.18 ? 360 LYS D C 1 ATOM 4311 O O . LYS D 1 140 ? -57.444 -5.205 -30.744 1.00 49.13 ? 360 LYS D O 1 ATOM 4312 C CB . LYS D 1 140 ? -58.427 -7.676 -28.562 1.00 39.89 ? 360 LYS D CB 1 ATOM 4313 C CG . LYS D 1 140 ? -59.248 -8.928 -28.271 1.00 37.84 ? 360 LYS D CG 1 ATOM 4314 C CD . LYS D 1 140 ? -60.147 -9.429 -27.523 0.00 33.29 ? 360 LYS D CD 1 ATOM 4315 N N . ASN D 1 141 ? -58.614 -4.611 -28.914 1.00 37.56 ? 361 ASN D N 1 ATOM 4316 C CA . ASN D 1 141 ? -58.118 -3.224 -28.892 1.00 37.04 ? 361 ASN D CA 1 ATOM 4317 C C . ASN D 1 141 ? -56.625 -3.132 -28.614 1.00 40.68 ? 361 ASN D C 1 ATOM 4318 O O . ASN D 1 141 ? -55.947 -2.191 -29.037 1.00 37.86 ? 361 ASN D O 1 ATOM 4319 C CB . ASN D 1 141 ? -58.843 -2.398 -27.822 1.00 40.02 ? 361 ASN D CB 1 ATOM 4320 C CG . ASN D 1 141 ? -60.310 -2.187 -28.131 1.00 44.37 ? 361 ASN D CG 1 ATOM 4321 O OD1 . ASN D 1 141 ? -60.803 -2.580 -29.190 1.00 58.91 ? 361 ASN D OD1 1 ATOM 4322 N ND2 . ASN D 1 141 ? -61.021 -1.560 -27.198 1.00 44.92 ? 361 ASN D ND2 1 ATOM 4323 N N . GLN D 1 142 ? -56.130 -4.110 -27.867 1.00 39.51 ? 362 GLN D N 1 ATOM 4324 C CA . GLN D 1 142 ? -54.756 -4.115 -27.426 1.00 36.34 ? 362 GLN D CA 1 ATOM 4325 C C . GLN D 1 142 ? -54.200 -5.494 -27.630 1.00 36.09 ? 362 GLN D C 1 ATOM 4326 O O . GLN D 1 142 ? -54.921 -6.485 -27.486 1.00 31.90 ? 362 GLN D O 1 ATOM 4327 C CB . GLN D 1 142 ? -54.682 -3.730 -25.956 1.00 34.31 ? 362 GLN D CB 1 ATOM 4328 C CG . GLN D 1 142 ? -55.009 -2.272 -25.693 1.00 30.95 ? 362 GLN D CG 1 ATOM 4329 C CD . GLN D 1 142 ? -54.980 -1.939 -24.216 1.00 36.26 ? 362 GLN D CD 1 ATOM 4330 O OE1 . GLN D 1 142 ? -55.131 -2.820 -23.365 1.00 36.02 ? 362 GLN D OE1 1 ATOM 4331 N NE2 . GLN D 1 142 ? -54.791 -0.655 -23.901 1.00 30.67 ? 362 GLN D NE2 1 ATOM 4332 N N . VAL D 1 143 ? -52.921 -5.555 -27.993 1.00 36.24 ? 363 VAL D N 1 ATOM 4333 C CA . VAL D 1 143 ? -52.266 -6.829 -28.243 1.00 29.93 ? 363 VAL D CA 1 ATOM 4334 C C . VAL D 1 143 ? -51.104 -7.023 -27.303 1.00 29.20 ? 363 VAL D C 1 ATOM 4335 O O . VAL D 1 143 ? -50.571 -6.067 -26.742 1.00 34.44 ? 363 VAL D O 1 ATOM 4336 C CB . VAL D 1 143 ? -51.814 -6.981 -29.718 1.00 28.00 ? 363 VAL D CB 1 ATOM 4337 C CG1 . VAL D 1 143 ? -53.020 -6.919 -30.631 1.00 29.36 ? 363 VAL D CG1 1 ATOM 4338 C CG2 . VAL D 1 143 ? -50.789 -5.923 -30.108 1.00 24.21 ? 363 VAL D CG2 1 ATOM 4339 N N . SER D 1 144 ? -50.717 -8.280 -27.154 1.00 35.40 ? 364 SER D N 1 ATOM 4340 C CA . SER D 1 144 ? -49.693 -8.688 -26.214 1.00 31.96 ? 364 SER D CA 1 ATOM 4341 C C . SER D 1 144 ? -48.455 -9.109 -26.984 1.00 29.25 ? 364 SER D C 1 ATOM 4342 O O . SER D 1 144 ? -48.503 -10.028 -27.814 1.00 39.25 ? 364 SER D O 1 ATOM 4343 C CB . SER D 1 144 ? -50.195 -9.869 -25.374 1.00 30.95 ? 364 SER D CB 1 ATOM 4344 O OG . SER D 1 144 ? -51.503 -9.634 -24.890 1.00 30.19 ? 364 SER D OG 1 ATOM 4345 N N . LEU D 1 145 ? -47.358 -8.414 -26.724 1.00 28.26 ? 365 LEU D N 1 ATOM 4346 C CA . LEU D 1 145 ? -46.040 -8.797 -27.237 1.00 25.69 ? 365 LEU D CA 1 ATOM 4347 C C . LEU D 1 145 ? -45.333 -9.610 -26.176 1.00 30.53 ? 365 LEU D C 1 ATOM 4348 O O . LEU D 1 145 ? -45.241 -9.183 -25.014 1.00 24.34 ? 365 LEU D O 1 ATOM 4349 C CB . LEU D 1 145 ? -45.239 -7.551 -27.600 1.00 27.38 ? 365 LEU D CB 1 ATOM 4350 C CG . LEU D 1 145 ? -45.895 -6.643 -28.655 1.00 29.17 ? 365 LEU D CG 1 ATOM 4351 C CD1 . LEU D 1 145 ? -44.961 -5.516 -29.032 1.00 27.16 ? 365 LEU D CD1 1 ATOM 4352 C CD2 . LEU D 1 145 ? -46.287 -7.427 -29.899 1.00 26.41 ? 365 LEU D CD2 1 ATOM 4353 N N . THR D 1 146 ? -44.865 -10.793 -26.557 1.00 28.64 ? 366 THR D N 1 ATOM 4354 C CA . THR D 1 146 ? -44.290 -11.717 -25.590 1.00 30.43 ? 366 THR D CA 1 ATOM 4355 C C . THR D 1 146 ? -42.764 -11.830 -25.697 1.00 34.70 ? 366 THR D C 1 ATOM 4356 O O . THR D 1 146 ? -42.197 -12.022 -26.794 1.00 25.25 ? 366 THR D O 1 ATOM 4357 C CB . THR D 1 146 ? -44.935 -13.107 -25.713 1.00 30.92 ? 366 THR D CB 1 ATOM 4358 O OG1 . THR D 1 146 ? -46.348 -12.994 -25.486 1.00 34.43 ? 366 THR D OG1 1 ATOM 4359 C CG2 . THR D 1 146 ? -44.333 -14.081 -24.714 1.00 30.02 ? 366 THR D CG2 1 ATOM 4360 N N . CYS D 1 147 ? -42.111 -11.709 -24.546 1.00 22.86 ? 367 CYS D N 1 ATOM 4361 C CA . CYS D 1 147 ? -40.693 -12.005 -24.434 1.00 24.55 ? 367 CYS D CA 1 ATOM 4362 C C . CYS D 1 147 ? -40.442 -13.242 -23.561 1.00 26.89 ? 367 CYS D C 1 ATOM 4363 O O . CYS D 1 147 ? -40.522 -13.176 -22.327 1.00 27.38 ? 367 CYS D O 1 ATOM 4364 C CB . CYS D 1 147 ? -39.941 -10.794 -23.888 1.00 28.16 ? 367 CYS D CB 1 ATOM 4365 S SG . CYS D 1 147 ? -38.154 -10.909 -24.024 1.00 39.77 ? 367 CYS D SG 1 ATOM 4366 N N . VAL D 1 148 ? -40.161 -14.363 -24.220 1.00 28.29 ? 368 VAL D N 1 ATOM 4367 C CA . VAL D 1 148 ? -39.712 -15.601 -23.574 1.00 30.16 ? 368 VAL D CA 1 ATOM 4368 C C . VAL D 1 148 ? -38.221 -15.519 -23.274 1.00 31.75 ? 368 VAL D C 1 ATOM 4369 O O . VAL D 1 148 ? -37.405 -15.272 -24.177 1.00 29.90 ? 368 VAL D O 1 ATOM 4370 C CB . VAL D 1 148 ? -39.970 -16.830 -24.484 1.00 30.97 ? 368 VAL D CB 1 ATOM 4371 C CG1 . VAL D 1 148 ? -39.364 -18.111 -23.906 1.00 28.58 ? 368 VAL D CG1 1 ATOM 4372 C CG2 . VAL D 1 148 ? -41.464 -17.003 -24.703 1.00 31.78 ? 368 VAL D CG2 1 ATOM 4373 N N . VAL D 1 149 ? -37.887 -15.720 -22.000 1.00 27.57 ? 369 VAL D N 1 ATOM 4374 C CA . VAL D 1 149 ? -36.511 -15.760 -21.519 1.00 27.37 ? 369 VAL D CA 1 ATOM 4375 C C . VAL D 1 149 ? -36.285 -17.104 -20.799 1.00 31.56 ? 369 VAL D C 1 ATOM 4376 O O . VAL D 1 149 ? -36.748 -17.293 -19.668 1.00 32.85 ? 369 VAL D O 1 ATOM 4377 C CB . VAL D 1 149 ? -36.217 -14.589 -20.542 1.00 29.86 ? 369 VAL D CB 1 ATOM 4378 C CG1 . VAL D 1 149 ? -34.747 -14.561 -20.147 1.00 28.46 ? 369 VAL D CG1 1 ATOM 4379 C CG2 . VAL D 1 149 ? -36.630 -13.242 -21.132 1.00 27.94 ? 369 VAL D CG2 1 ATOM 4380 N N . LYS D 1 150 ? -35.572 -18.032 -21.437 1.00 33.43 ? 370 LYS D N 1 ATOM 4381 C CA . LYS D 1 150 ? -35.383 -19.373 -20.859 1.00 34.80 ? 370 LYS D CA 1 ATOM 4382 C C . LYS D 1 150 ? -33.934 -19.853 -20.807 1.00 37.66 ? 370 LYS D C 1 ATOM 4383 O O . LYS D 1 150 ? -33.077 -19.349 -21.529 1.00 40.98 ? 370 LYS D O 1 ATOM 4384 C CB . LYS D 1 150 ? -36.262 -20.411 -21.576 1.00 38.65 ? 370 LYS D CB 1 ATOM 4385 C CG . LYS D 1 150 ? -35.721 -20.932 -22.897 1.00 43.36 ? 370 LYS D CG 1 ATOM 4386 C CD . LYS D 1 150 ? -36.436 -22.214 -23.318 1.00 47.45 ? 370 LYS D CD 1 ATOM 4387 N N . GLY D 1 151 ? -33.680 -20.832 -19.938 1.00 31.78 ? 371 GLY D N 1 ATOM 4388 C CA . GLY D 1 151 ? -32.386 -21.504 -19.863 1.00 27.58 ? 371 GLY D CA 1 ATOM 4389 C C . GLY D 1 151 ? -31.348 -20.778 -19.035 1.00 34.42 ? 371 GLY D C 1 ATOM 4390 O O . GLY D 1 151 ? -30.150 -20.974 -19.238 1.00 41.75 ? 371 GLY D O 1 ATOM 4391 N N . PHE D 1 152 ? -31.806 -19.944 -18.102 1.00 28.66 ? 372 PHE D N 1 ATOM 4392 C CA . PHE D 1 152 ? -30.909 -19.095 -17.342 1.00 33.13 ? 372 PHE D CA 1 ATOM 4393 C C . PHE D 1 152 ? -30.705 -19.546 -15.913 1.00 30.56 ? 372 PHE D C 1 ATOM 4394 O O . PHE D 1 152 ? -31.622 -20.046 -15.268 1.00 26.62 ? 372 PHE D O 1 ATOM 4395 C CB . PHE D 1 152 ? -31.288 -17.594 -17.407 1.00 34.28 ? 372 PHE D CB 1 ATOM 4396 C CG . PHE D 1 152 ? -32.596 -17.218 -16.730 1.00 32.14 ? 372 PHE D CG 1 ATOM 4397 C CD1 . PHE D 1 152 ? -33.775 -17.137 -17.462 1.00 32.06 ? 372 PHE D CD1 1 ATOM 4398 C CD2 . PHE D 1 152 ? -32.627 -16.854 -15.382 1.00 33.24 ? 372 PHE D CD2 1 ATOM 4399 C CE1 . PHE D 1 152 ? -34.966 -16.750 -16.855 1.00 35.56 ? 372 PHE D CE1 1 ATOM 4400 C CE2 . PHE D 1 152 ? -33.808 -16.469 -14.771 1.00 30.18 ? 372 PHE D CE2 1 ATOM 4401 C CZ . PHE D 1 152 ? -34.982 -16.414 -15.509 1.00 38.31 ? 372 PHE D CZ 1 ATOM 4402 N N . TYR D 1 153 ? -29.469 -19.384 -15.456 1.00 31.34 ? 373 TYR D N 1 ATOM 4403 C CA . TYR D 1 153 ? -29.099 -19.630 -14.076 1.00 30.42 ? 373 TYR D CA 1 ATOM 4404 C C . TYR D 1 153 ? -28.007 -18.636 -13.680 1.00 32.18 ? 373 TYR D C 1 ATOM 4405 O O . TYR D 1 153 ? -27.140 -18.320 -14.503 1.00 34.10 ? 373 TYR D O 1 ATOM 4406 C CB . TYR D 1 153 ? -28.629 -21.093 -13.852 1.00 27.84 ? 373 TYR D CB 1 ATOM 4407 C CG . TYR D 1 153 ? -28.613 -21.422 -12.379 1.00 29.62 ? 373 TYR D CG 1 ATOM 4408 C CD1 . TYR D 1 153 ? -27.462 -21.223 -11.612 1.00 27.13 ? 373 TYR D CD1 1 ATOM 4409 C CD2 . TYR D 1 153 ? -29.770 -21.845 -11.735 1.00 26.83 ? 373 TYR D CD2 1 ATOM 4410 C CE1 . TYR D 1 153 ? -27.468 -21.465 -10.251 1.00 28.93 ? 373 TYR D CE1 1 ATOM 4411 C CE2 . TYR D 1 153 ? -29.780 -22.099 -10.377 1.00 25.45 ? 373 TYR D CE2 1 ATOM 4412 C CZ . TYR D 1 153 ? -28.632 -21.908 -9.642 1.00 29.08 ? 373 TYR D CZ 1 ATOM 4413 O OH . TYR D 1 153 ? -28.641 -22.160 -8.283 1.00 37.83 ? 373 TYR D OH 1 ATOM 4414 N N . PRO D 1 154 ? -28.053 -18.112 -12.434 1.00 30.91 ? 374 PRO D N 1 ATOM 4415 C CA . PRO D 1 154 ? -29.137 -18.226 -11.449 1.00 32.79 ? 374 PRO D CA 1 ATOM 4416 C C . PRO D 1 154 ? -30.373 -17.395 -11.850 1.00 32.97 ? 374 PRO D C 1 ATOM 4417 O O . PRO D 1 154 ? -30.388 -16.802 -12.925 1.00 35.09 ? 374 PRO D O 1 ATOM 4418 C CB . PRO D 1 154 ? -28.489 -17.728 -10.140 1.00 28.14 ? 374 PRO D CB 1 ATOM 4419 C CG . PRO D 1 154 ? -27.361 -16.871 -10.570 1.00 29.45 ? 374 PRO D CG 1 ATOM 4420 C CD . PRO D 1 154 ? -26.865 -17.443 -11.877 1.00 29.29 ? 374 PRO D CD 1 ATOM 4421 N N . SER D 1 155 ? -31.399 -17.374 -11.002 1.00 35.19 ? 375 SER D N 1 ATOM 4422 C CA . SER D 1 155 ? -32.708 -16.792 -11.345 1.00 29.97 ? 375 SER D CA 1 ATOM 4423 C C . SER D 1 155 ? -32.728 -15.249 -11.315 1.00 37.19 ? 375 SER D C 1 ATOM 4424 O O . SER D 1 155 ? -33.691 -14.636 -11.766 1.00 36.60 ? 375 SER D O 1 ATOM 4425 C CB . SER D 1 155 ? -33.762 -17.322 -10.385 1.00 29.27 ? 375 SER D CB 1 ATOM 4426 O OG . SER D 1 155 ? -33.446 -16.937 -9.056 1.00 27.99 ? 375 SER D OG 1 ATOM 4427 N N . ASP D 1 156 ? -31.676 -14.645 -10.765 1.00 32.40 ? 376 ASP D N 1 ATOM 4428 C CA . ASP D 1 156 ? -31.482 -13.192 -10.772 1.00 35.79 ? 376 ASP D CA 1 ATOM 4429 C C . ASP D 1 156 ? -31.438 -12.654 -12.193 1.00 36.57 ? 376 ASP D C 1 ATOM 4430 O O . ASP D 1 156 ? -30.623 -13.087 -13.012 1.00 33.23 ? 376 ASP D O 1 ATOM 4431 C CB . ASP D 1 156 ? -30.188 -12.830 -10.059 1.00 31.62 ? 376 ASP D CB 1 ATOM 4432 C CG . ASP D 1 156 ? -30.141 -13.366 -8.636 1.00 41.90 ? 376 ASP D CG 1 ATOM 4433 O OD1 . ASP D 1 156 ? -29.038 -13.732 -8.178 1.00 47.01 ? 376 ASP D OD1 1 ATOM 4434 O OD2 . ASP D 1 156 ? -31.207 -13.428 -7.981 1.00 40.96 ? 376 ASP D OD2 1 ATOM 4435 N N . ILE D 1 157 ? -32.323 -11.708 -12.472 1.00 31.63 ? 377 ILE D N 1 ATOM 4436 C CA . ILE D 1 157 ? -32.532 -11.242 -13.831 1.00 34.66 ? 377 ILE D CA 1 ATOM 4437 C C . ILE D 1 157 ? -33.390 -9.985 -13.813 1.00 34.46 ? 377 ILE D C 1 ATOM 4438 O O . ILE D 1 157 ? -34.195 -9.785 -12.911 1.00 38.45 ? 377 ILE D O 1 ATOM 4439 C CB . ILE D 1 157 ? -33.163 -12.354 -14.712 1.00 27.62 ? 377 ILE D CB 1 ATOM 4440 C CG1 . ILE D 1 157 ? -32.985 -12.033 -16.192 1.00 27.36 ? 377 ILE D CG1 1 ATOM 4441 C CG2 . ILE D 1 157 ? -34.633 -12.603 -14.353 1.00 30.66 ? 377 ILE D CG2 1 ATOM 4442 C CD1 . ILE D 1 157 ? -33.217 -13.214 -17.096 1.00 26.36 ? 377 ILE D CD1 1 ATOM 4443 N N . ALA D 1 158 ? -33.165 -9.125 -14.796 1.00 33.58 ? 378 ALA D N 1 ATOM 4444 C CA . ALA D 1 158 ? -33.975 -7.952 -15.013 1.00 28.44 ? 378 ALA D CA 1 ATOM 4445 C C . ALA D 1 158 ? -34.459 -8.025 -16.456 1.00 33.70 ? 378 ALA D C 1 ATOM 4446 O O . ALA D 1 158 ? -33.669 -8.306 -17.357 1.00 27.43 ? 378 ALA D O 1 ATOM 4447 C CB . ALA D 1 158 ? -33.147 -6.701 -14.803 1.00 26.07 ? 378 ALA D CB 1 ATOM 4448 N N . VAL D 1 159 ? -35.753 -7.783 -16.659 1.00 32.15 ? 379 VAL D N 1 ATOM 4449 C CA . VAL D 1 159 ? -36.358 -7.750 -17.985 1.00 30.10 ? 379 VAL D CA 1 ATOM 4450 C C . VAL D 1 159 ? -37.080 -6.415 -18.130 1.00 35.48 ? 379 VAL D C 1 ATOM 4451 O O . VAL D 1 159 ? -37.822 -6.018 -17.228 1.00 35.43 ? 379 VAL D O 1 ATOM 4452 C CB . VAL D 1 159 ? -37.377 -8.895 -18.168 1.00 32.39 ? 379 VAL D CB 1 ATOM 4453 C CG1 . VAL D 1 159 ? -37.928 -8.907 -19.591 1.00 30.58 ? 379 VAL D CG1 1 ATOM 4454 C CG2 . VAL D 1 159 ? -36.750 -10.242 -17.814 1.00 32.17 ? 379 VAL D CG2 1 ATOM 4455 N N . GLU D 1 160 ? -36.862 -5.733 -19.260 1.00 35.36 ? 380 GLU D N 1 ATOM 4456 C CA . GLU D 1 160 ? -37.503 -4.444 -19.550 1.00 32.71 ? 380 GLU D CA 1 ATOM 4457 C C . GLU D 1 160 ? -37.883 -4.275 -21.017 1.00 38.14 ? 380 GLU D C 1 ATOM 4458 O O . GLU D 1 160 ? -37.320 -4.925 -21.904 1.00 37.22 ? 380 GLU D O 1 ATOM 4459 C CB . GLU D 1 160 ? -36.618 -3.283 -19.089 1.00 38.03 ? 380 GLU D CB 1 ATOM 4460 C CG . GLU D 1 160 ? -36.780 -2.981 -17.610 1.00 42.26 ? 380 GLU D CG 1 ATOM 4461 C CD . GLU D 1 160 ? -35.648 -2.170 -17.018 1.00 49.25 ? 380 GLU D CD 1 ATOM 4462 O OE1 . GLU D 1 160 ? -35.322 -1.089 -17.555 1.00 47.23 ? 380 GLU D OE1 1 ATOM 4463 O OE2 . GLU D 1 160 ? -35.104 -2.607 -15.985 1.00 60.84 ? 380 GLU D OE2 1 ATOM 4464 N N . TRP D 1 161 ? -38.854 -3.398 -21.261 1.00 41.04 ? 381 TRP D N 1 ATOM 4465 C CA . TRP D 1 161 ? -39.355 -3.131 -22.605 1.00 28.32 ? 381 TRP D CA 1 ATOM 4466 C C . TRP D 1 161 ? -39.140 -1.696 -22.971 1.00 31.19 ? 381 TRP D C 1 ATOM 4467 O O . TRP D 1 161 ? -39.198 -0.811 -22.113 1.00 26.41 ? 381 TRP D O 1 ATOM 4468 C CB . TRP D 1 161 ? -40.843 -3.437 -22.690 1.00 27.83 ? 381 TRP D CB 1 ATOM 4469 C CG . TRP D 1 161 ? -41.217 -4.896 -22.825 1.00 25.82 ? 381 TRP D CG 1 ATOM 4470 C CD1 . TRP D 1 161 ? -41.588 -5.774 -21.813 1.00 25.67 ? 381 TRP D CD1 1 ATOM 4471 C CD2 . TRP D 1 161 ? -41.322 -5.685 -24.072 1.00 24.89 ? 381 TRP D CD2 1 ATOM 4472 N NE1 . TRP D 1 161 ? -41.891 -7.015 -22.328 1.00 29.64 ? 381 TRP D NE1 1 ATOM 4473 C CE2 . TRP D 1 161 ? -41.753 -7.028 -23.673 1.00 25.15 ? 381 TRP D CE2 1 ATOM 4474 C CE3 . TRP D 1 161 ? -41.099 -5.419 -25.418 1.00 28.28 ? 381 TRP D CE3 1 ATOM 4475 C CZ2 . TRP D 1 161 ? -41.948 -8.042 -24.596 1.00 31.57 ? 381 TRP D CZ2 1 ATOM 4476 C CZ3 . TRP D 1 161 ? -41.292 -6.453 -26.348 1.00 27.50 ? 381 TRP D CZ3 1 ATOM 4477 C CH2 . TRP D 1 161 ? -41.710 -7.733 -25.944 1.00 31.32 ? 381 TRP D CH2 1 ATOM 4478 N N . GLU D 1 162 ? -38.914 -1.447 -24.261 1.00 25.44 ? 382 GLU D N 1 ATOM 4479 C CA . GLU D 1 162 ? -38.669 -0.106 -24.748 1.00 27.78 ? 382 GLU D CA 1 ATOM 4480 C C . GLU D 1 162 ? -39.083 0.053 -26.206 1.00 30.65 ? 382 GLU D C 1 ATOM 4481 O O . GLU D 1 162 ? -39.276 -0.934 -26.917 1.00 26.41 ? 382 GLU D O 1 ATOM 4482 C CB . GLU D 1 162 ? -37.192 0.291 -24.560 1.00 31.30 ? 382 GLU D CB 1 ATOM 4483 C CG . GLU D 1 162 ? -36.187 -0.533 -25.358 1.00 36.62 ? 382 GLU D CG 1 ATOM 4484 C CD . GLU D 1 162 ? -34.753 -0.094 -25.126 1.00 44.56 ? 382 GLU D CD 1 ATOM 4485 O OE1 . GLU D 1 162 ? -34.156 0.499 -26.051 1.00 49.40 ? 382 GLU D OE1 1 ATOM 4486 O OE2 . GLU D 1 162 ? -34.223 -0.327 -24.018 1.00 51.71 ? 382 GLU D OE2 1 ATOM 4487 N N . SER D 1 163 ? -39.234 1.308 -26.617 1.00 33.85 ? 383 SER D N 1 ATOM 4488 C CA . SER D 1 163 ? -39.527 1.677 -27.993 1.00 38.52 ? 383 SER D CA 1 ATOM 4489 C C . SER D 1 163 ? -39.087 3.115 -28.206 1.00 34.22 ? 383 SER D C 1 ATOM 4490 O O . SER D 1 163 ? -39.396 3.981 -27.395 1.00 34.12 ? 383 SER D O 1 ATOM 4491 C CB . SER D 1 163 ? -41.018 1.543 -28.294 1.00 42.11 ? 383 SER D CB 1 ATOM 4492 O OG . SER D 1 163 ? -41.221 1.316 -29.680 1.00 33.44 ? 383 SER D OG 1 ATOM 4493 N N . ASN D 1 164 ? -38.359 3.353 -29.293 1.00 34.16 ? 384 ASN D N 1 ATOM 4494 C CA . ASN D 1 164 ? -37.781 4.669 -29.611 1.00 36.07 ? 384 ASN D CA 1 ATOM 4495 C C . ASN D 1 164 ? -36.894 5.266 -28.530 1.00 38.58 ? 384 ASN D C 1 ATOM 4496 O O . ASN D 1 164 ? -36.940 6.470 -28.287 1.00 38.58 ? 384 ASN D O 1 ATOM 4497 C CB . ASN D 1 164 ? -38.877 5.659 -29.988 1.00 43.83 ? 384 ASN D CB 1 ATOM 4498 C CG . ASN D 1 164 ? -39.474 5.354 -31.333 1.00 47.48 ? 384 ASN D CG 1 ATOM 4499 O OD1 . ASN D 1 164 ? -38.747 5.141 -32.305 1.00 44.91 ? 384 ASN D OD1 1 ATOM 4500 N ND2 . ASN D 1 164 ? -40.799 5.313 -31.398 1.00 47.93 ? 384 ASN D ND2 1 ATOM 4501 N N . GLY D 1 165 ? -36.081 4.420 -27.900 1.00 37.32 ? 385 GLY D N 1 ATOM 4502 C CA . GLY D 1 165 ? -35.189 4.848 -26.824 1.00 43.58 ? 385 GLY D CA 1 ATOM 4503 C C . GLY D 1 165 ? -35.945 5.220 -25.562 1.00 44.56 ? 385 GLY D C 1 ATOM 4504 O O . GLY D 1 165 ? -35.378 5.777 -24.628 1.00 44.45 ? 385 GLY D O 1 ATOM 4505 N N . GLN D 1 166 ? -37.232 4.897 -25.533 1.00 49.58 ? 386 GLN D N 1 ATOM 4506 C CA . GLN D 1 166 ? -38.072 5.267 -24.420 1.00 47.76 ? 386 GLN D CA 1 ATOM 4507 C C . GLN D 1 166 ? -38.623 4.016 -23.774 1.00 42.27 ? 386 GLN D C 1 ATOM 4508 O O . GLN D 1 166 ? -39.058 3.102 -24.475 1.00 42.77 ? 386 GLN D O 1 ATOM 4509 C CB . GLN D 1 166 ? -39.211 6.177 -24.890 1.00 56.65 ? 386 GLN D CB 1 ATOM 4510 C CG . GLN D 1 166 ? -39.432 7.382 -23.995 1.00 59.79 ? 386 GLN D CG 1 ATOM 4511 C CD . GLN D 1 166 ? -38.262 8.343 -24.037 1.00 58.12 ? 386 GLN D CD 1 ATOM 4512 O OE1 . GLN D 1 166 ? -37.879 8.820 -25.106 1.00 51.40 ? 386 GLN D OE1 1 ATOM 4513 N NE2 . GLN D 1 166 ? -37.681 8.626 -22.872 1.00 45.27 ? 386 GLN D NE2 1 ATOM 4514 N N . PRO D 1 167 ? -38.593 3.966 -22.431 1.00 39.60 ? 387 PRO D N 1 ATOM 4515 C CA . PRO D 1 167 ? -39.134 2.823 -21.715 1.00 37.67 ? 387 PRO D CA 1 ATOM 4516 C C . PRO D 1 167 ? -40.638 2.691 -21.932 1.00 37.50 ? 387 PRO D C 1 ATOM 4517 O O . PRO D 1 167 ? -41.371 3.680 -21.854 1.00 34.18 ? 387 PRO D O 1 ATOM 4518 C CB . PRO D 1 167 ? -38.822 3.139 -20.237 1.00 36.65 ? 387 PRO D CB 1 ATOM 4519 C CG . PRO D 1 167 ? -38.586 4.607 -20.193 1.00 41.96 ? 387 PRO D CG 1 ATOM 4520 C CD . PRO D 1 167 ? -38.000 4.966 -21.522 1.00 40.27 ? 387 PRO D CD 1 ATOM 4521 N N . GLU D 1 168 ? -41.069 1.470 -22.225 1.00 35.64 ? 388 GLU D N 1 ATOM 4522 C CA . GLU D 1 168 ? -42.473 1.133 -22.332 1.00 35.24 ? 388 GLU D CA 1 ATOM 4523 C C . GLU D 1 168 ? -42.836 0.480 -21.017 1.00 43.28 ? 388 GLU D C 1 ATOM 4524 O O . GLU D 1 168 ? -42.285 -0.560 -20.678 1.00 53.90 ? 388 GLU D O 1 ATOM 4525 C CB . GLU D 1 168 ? -42.680 0.153 -23.486 1.00 35.42 ? 388 GLU D CB 1 ATOM 4526 C CG . GLU D 1 168 ? -42.537 0.776 -24.867 1.00 34.40 ? 388 GLU D CG 1 ATOM 4527 C CD . GLU D 1 168 ? -43.687 1.707 -25.183 1.00 44.88 ? 388 GLU D CD 1 ATOM 4528 O OE1 . GLU D 1 168 ? -44.853 1.308 -24.954 1.00 46.42 ? 388 GLU D OE1 1 ATOM 4529 O OE2 . GLU D 1 168 ? -43.425 2.839 -25.639 1.00 44.76 ? 388 GLU D OE2 1 ATOM 4530 N N . ASN D 1 169 ? -43.747 1.088 -20.269 1.00 47.55 ? 389 ASN D N 1 ATOM 4531 C CA . ASN D 1 169 ? -44.033 0.638 -18.905 1.00 47.22 ? 389 ASN D CA 1 ATOM 4532 C C . ASN D 1 169 ? -45.270 -0.256 -18.746 1.00 51.28 ? 389 ASN D C 1 ATOM 4533 O O . ASN D 1 169 ? -45.492 -0.805 -17.660 1.00 51.12 ? 389 ASN D O 1 ATOM 4534 C CB . ASN D 1 169 ? -44.113 1.834 -17.941 1.00 59.48 ? 389 ASN D CB 1 ATOM 4535 C CG . ASN D 1 169 ? -42.772 2.527 -17.745 1.00 67.69 ? 389 ASN D CG 1 ATOM 4536 O OD1 . ASN D 1 169 ? -41.771 1.900 -17.384 1.00 66.07 ? 389 ASN D OD1 1 ATOM 4537 N ND2 . ASN D 1 169 ? -42.751 3.836 -17.971 1.00 67.74 ? 389 ASN D ND2 1 ATOM 4538 N N . ASN D 1 170 ? -46.055 -0.425 -19.812 1.00 33.08 ? 390 ASN D N 1 ATOM 4539 C CA . ASN D 1 170 ? -47.275 -1.250 -19.745 1.00 36.48 ? 390 ASN D CA 1 ATOM 4540 C C . ASN D 1 170 ? -47.018 -2.765 -19.861 1.00 32.51 ? 390 ASN D C 1 ATOM 4541 O O . ASN D 1 170 ? -47.658 -3.471 -20.657 1.00 30.59 ? 390 ASN D O 1 ATOM 4542 C CB . ASN D 1 170 ? -48.289 -0.790 -20.800 1.00 41.82 ? 390 ASN D CB 1 ATOM 4543 C CG . ASN D 1 170 ? -49.720 -1.121 -20.428 1.00 43.77 ? 390 ASN D CG 1 ATOM 4544 O OD1 . ASN D 1 170 ? -50.104 -1.071 -19.258 1.00 38.24 ? 390 ASN D OD1 1 ATOM 4545 N ND2 . ASN D 1 170 ? -50.531 -1.434 -21.437 1.00 35.86 ? 390 ASN D ND2 1 ATOM 4546 N N . TYR D 1 171 ? -46.081 -3.269 -19.067 1.00 32.41 ? 391 TYR D N 1 ATOM 4547 C CA . TYR D 1 171 ? -45.754 -4.691 -19.124 1.00 28.68 ? 391 TYR D CA 1 ATOM 4548 C C . TYR D 1 171 ? -45.811 -5.395 -17.783 1.00 32.13 ? 391 TYR D C 1 ATOM 4549 O O . TYR D 1 171 ? -45.756 -4.763 -16.720 1.00 29.06 ? 391 TYR D O 1 ATOM 4550 C CB . TYR D 1 171 ? -44.392 -4.925 -19.778 1.00 30.62 ? 391 TYR D CB 1 ATOM 4551 C CG . TYR D 1 171 ? -43.202 -4.399 -19.010 1.00 34.87 ? 391 TYR D CG 1 ATOM 4552 C CD1 . TYR D 1 171 ? -42.485 -5.219 -18.125 1.00 34.72 ? 391 TYR D CD1 1 ATOM 4553 C CD2 . TYR D 1 171 ? -42.779 -3.087 -19.183 1.00 36.99 ? 391 TYR D CD2 1 ATOM 4554 C CE1 . TYR D 1 171 ? -41.384 -4.729 -17.434 1.00 40.20 ? 391 TYR D CE1 1 ATOM 4555 C CE2 . TYR D 1 171 ? -41.686 -2.588 -18.497 1.00 42.19 ? 391 TYR D CE2 1 ATOM 4556 C CZ . TYR D 1 171 ? -40.993 -3.406 -17.631 1.00 40.44 ? 391 TYR D CZ 1 ATOM 4557 O OH . TYR D 1 171 ? -39.913 -2.878 -16.987 1.00 35.84 ? 391 TYR D OH 1 ATOM 4558 N N . LYS D 1 172 ? -45.926 -6.715 -17.854 1.00 28.45 ? 392 LYS D N 1 ATOM 4559 C CA . LYS D 1 172 ? -45.883 -7.558 -16.671 1.00 33.10 ? 392 LYS D CA 1 ATOM 4560 C C . LYS D 1 172 ? -45.016 -8.756 -16.997 1.00 34.16 ? 392 LYS D C 1 ATOM 4561 O O . LYS D 1 172 ? -45.062 -9.310 -18.113 1.00 28.60 ? 392 LYS D O 1 ATOM 4562 C CB . LYS D 1 172 ? -47.286 -8.007 -16.237 1.00 31.29 ? 392 LYS D CB 1 ATOM 4563 C CG . LYS D 1 172 ? -48.198 -6.886 -15.750 1.00 35.15 ? 392 LYS D CG 1 ATOM 4564 C CD . LYS D 1 172 ? -48.004 -6.552 -14.272 1.00 34.17 ? 392 LYS D CD 1 ATOM 4565 C CE . LYS D 1 172 ? -48.757 -5.276 -13.922 1.00 36.73 ? 392 LYS D CE 1 ATOM 4566 N NZ . LYS D 1 172 ? -48.563 -4.867 -12.502 1.00 47.91 ? 392 LYS D NZ 1 ATOM 4567 N N . THR D 1 173 ? -44.207 -9.146 -16.025 1.00 26.77 ? 393 THR D N 1 ATOM 4568 C CA . THR D 1 173 ? -43.269 -10.232 -16.222 1.00 29.95 ? 393 THR D CA 1 ATOM 4569 C C . THR D 1 173 ? -43.545 -11.243 -15.130 1.00 35.99 ? 393 THR D C 1 ATOM 4570 O O . THR D 1 173 ? -43.803 -10.868 -13.983 1.00 29.54 ? 393 THR D O 1 ATOM 4571 C CB . THR D 1 173 ? -41.814 -9.722 -16.167 1.00 28.50 ? 393 THR D CB 1 ATOM 4572 O OG1 . THR D 1 173 ? -41.614 -8.753 -17.206 1.00 25.17 ? 393 THR D OG1 1 ATOM 4573 C CG2 . THR D 1 173 ? -40.819 -10.859 -16.381 1.00 28.64 ? 393 THR D CG2 1 ATOM 4574 N N . THR D 1 174 ? -43.517 -12.521 -15.486 1.00 31.59 ? 394 THR D N 1 ATOM 4575 C CA . THR D 1 174 ? -43.775 -13.554 -14.493 1.00 34.73 ? 394 THR D CA 1 ATOM 4576 C C . THR D 1 174 ? -42.578 -13.718 -13.549 1.00 38.92 ? 394 THR D C 1 ATOM 4577 O O . THR D 1 174 ? -41.459 -13.286 -13.875 1.00 34.63 ? 394 THR D O 1 ATOM 4578 C CB . THR D 1 174 ? -44.140 -14.898 -15.142 1.00 31.01 ? 394 THR D CB 1 ATOM 4579 O OG1 . THR D 1 174 ? -43.003 -15.432 -15.815 1.00 29.42 ? 394 THR D OG1 1 ATOM 4580 C CG2 . THR D 1 174 ? -45.279 -14.730 -16.127 1.00 30.48 ? 394 THR D CG2 1 ATOM 4581 N N . PRO D 1 175 ? -42.812 -14.299 -12.357 1.00 38.13 ? 395 PRO D N 1 ATOM 4582 C CA . PRO D 1 175 ? -41.670 -14.717 -11.551 1.00 41.34 ? 395 PRO D CA 1 ATOM 4583 C C . PRO D 1 175 ? -40.929 -15.833 -12.281 1.00 35.61 ? 395 PRO D C 1 ATOM 4584 O O . PRO D 1 175 ? -41.566 -16.591 -13.027 1.00 35.72 ? 395 PRO D O 1 ATOM 4585 C CB . PRO D 1 175 ? -42.327 -15.266 -10.270 1.00 42.34 ? 395 PRO D CB 1 ATOM 4586 C CG . PRO D 1 175 ? -43.639 -14.549 -10.187 1.00 40.99 ? 395 PRO D CG 1 ATOM 4587 C CD . PRO D 1 175 ? -44.085 -14.458 -11.626 1.00 37.60 ? 395 PRO D CD 1 ATOM 4588 N N . PRO D 1 176 ? -39.593 -15.924 -12.095 1.00 33.71 ? 396 PRO D N 1 ATOM 4589 C CA . PRO D 1 176 ? -38.833 -17.030 -12.676 1.00 32.99 ? 396 PRO D CA 1 ATOM 4590 C C . PRO D 1 176 ? -39.373 -18.381 -12.233 1.00 33.70 ? 396 PRO D C 1 ATOM 4591 O O . PRO D 1 176 ? -39.678 -18.583 -11.044 1.00 29.91 ? 396 PRO D O 1 ATOM 4592 C CB . PRO D 1 176 ? -37.422 -16.806 -12.139 1.00 29.99 ? 396 PRO D CB 1 ATOM 4593 C CG . PRO D 1 176 ? -37.342 -15.335 -11.925 1.00 28.13 ? 396 PRO D CG 1 ATOM 4594 C CD . PRO D 1 176 ? -38.709 -14.923 -11.474 1.00 27.24 ? 396 PRO D CD 1 ATOM 4595 N N . VAL D 1 177 ? -39.522 -19.286 -13.193 1.00 27.07 ? 397 VAL D N 1 ATOM 4596 C CA . VAL D 1 177 ? -39.977 -20.629 -12.883 1.00 32.59 ? 397 VAL D CA 1 ATOM 4597 C C . VAL D 1 177 ? -38.846 -21.629 -13.089 1.00 33.88 ? 397 VAL D C 1 ATOM 4598 O O . VAL D 1 177 ? -38.209 -21.637 -14.134 1.00 33.46 ? 397 VAL D O 1 ATOM 4599 C CB . VAL D 1 177 ? -41.206 -21.020 -13.727 1.00 33.39 ? 397 VAL D CB 1 ATOM 4600 C CG1 . VAL D 1 177 ? -41.624 -22.458 -13.453 1.00 27.45 ? 397 VAL D CG1 1 ATOM 4601 C CG2 . VAL D 1 177 ? -42.356 -20.050 -13.473 1.00 32.90 ? 397 VAL D CG2 1 ATOM 4602 N N . LEU D 1 178 ? -38.601 -22.459 -12.075 1.00 42.03 ? 398 LEU D N 1 ATOM 4603 C CA . LEU D 1 178 ? -37.659 -23.574 -12.172 1.00 37.69 ? 398 LEU D CA 1 ATOM 4604 C C . LEU D 1 178 ? -38.116 -24.575 -13.235 1.00 41.81 ? 398 LEU D C 1 ATOM 4605 O O . LEU D 1 178 ? -39.223 -25.115 -13.163 1.00 45.67 ? 398 LEU D O 1 ATOM 4606 C CB . LEU D 1 178 ? -37.509 -24.258 -10.804 1.00 40.27 ? 398 LEU D CB 1 ATOM 4607 C CG . LEU D 1 178 ? -36.479 -25.391 -10.680 1.00 42.27 ? 398 LEU D CG 1 ATOM 4608 C CD1 . LEU D 1 178 ? -35.062 -24.841 -10.599 1.00 35.90 ? 398 LEU D CD1 1 ATOM 4609 C CD2 . LEU D 1 178 ? -36.775 -26.289 -9.488 1.00 31.23 ? 398 LEU D CD2 1 ATOM 4610 N N . ASP D 1 179 ? -37.267 -24.800 -14.234 1.00 41.02 ? 399 ASP D N 1 ATOM 4611 C CA . ASP D 1 179 ? -37.571 -25.730 -15.318 1.00 34.52 ? 399 ASP D CA 1 ATOM 4612 C C . ASP D 1 179 ? -36.946 -27.097 -15.010 1.00 36.13 ? 399 ASP D C 1 ATOM 4613 O O . ASP D 1 179 ? -36.090 -27.210 -14.135 1.00 30.88 ? 399 ASP D O 1 ATOM 4614 C CB . ASP D 1 179 ? -37.064 -25.172 -16.663 1.00 33.78 ? 399 ASP D CB 1 ATOM 4615 C CG . ASP D 1 179 ? -37.867 -25.677 -17.867 1.00 44.54 ? 399 ASP D CG 1 ATOM 4616 O OD1 . ASP D 1 179 ? -38.733 -26.573 -17.717 1.00 51.42 ? 399 ASP D OD1 1 ATOM 4617 O OD2 . ASP D 1 179 ? -37.623 -25.176 -18.987 1.00 46.81 ? 399 ASP D OD2 1 ATOM 4618 N N . SER D 1 180 ? -37.360 -28.128 -15.745 1.00 42.26 ? 400 SER D N 1 ATOM 4619 C CA . SER D 1 180 ? -36.940 -29.504 -15.464 1.00 44.65 ? 400 SER D CA 1 ATOM 4620 C C . SER D 1 180 ? -35.441 -29.755 -15.657 1.00 43.98 ? 400 SER D C 1 ATOM 4621 O O . SER D 1 180 ? -34.914 -30.746 -15.162 1.00 40.47 ? 400 SER D O 1 ATOM 4622 C CB . SER D 1 180 ? -37.761 -30.505 -16.288 1.00 41.16 ? 400 SER D CB 1 ATOM 4623 O OG . SER D 1 180 ? -37.570 -30.301 -17.680 1.00 43.59 ? 400 SER D OG 1 ATOM 4624 N N . ASP D 1 181 ? -34.754 -28.859 -16.360 1.00 48.52 ? 401 ASP D N 1 ATOM 4625 C CA . ASP D 1 181 ? -33.322 -29.041 -16.596 1.00 41.18 ? 401 ASP D CA 1 ATOM 4626 C C . ASP D 1 181 ? -32.425 -28.332 -15.582 1.00 39.94 ? 401 ASP D C 1 ATOM 4627 O O . ASP D 1 181 ? -31.206 -28.302 -15.739 1.00 54.70 ? 401 ASP D O 1 ATOM 4628 C CB . ASP D 1 181 ? -32.947 -28.666 -18.037 1.00 41.67 ? 401 ASP D CB 1 ATOM 4629 C CG . ASP D 1 181 ? -32.859 -27.160 -18.264 1.00 44.76 ? 401 ASP D CG 1 ATOM 4630 O OD1 . ASP D 1 181 ? -33.032 -26.364 -17.308 1.00 34.64 ? 401 ASP D OD1 1 ATOM 4631 O OD2 . ASP D 1 181 ? -32.603 -26.785 -19.427 1.00 36.80 ? 401 ASP D OD2 1 ATOM 4632 N N . GLY D 1 182 ? -33.024 -27.758 -14.546 1.00 34.07 ? 402 GLY D N 1 ATOM 4633 C CA . GLY D 1 182 ? -32.247 -27.092 -13.514 1.00 31.84 ? 402 GLY D CA 1 ATOM 4634 C C . GLY D 1 182 ? -32.087 -25.589 -13.670 1.00 30.96 ? 402 GLY D C 1 ATOM 4635 O O . GLY D 1 182 ? -31.643 -24.923 -12.734 1.00 23.58 ? 402 GLY D O 1 ATOM 4636 N N . SER D 1 183 ? -32.440 -25.059 -14.844 1.00 28.25 ? 403 SER D N 1 ATOM 4637 C CA . SER D 1 183 ? -32.424 -23.608 -15.090 1.00 31.12 ? 403 SER D CA 1 ATOM 4638 C C . SER D 1 183 ? -33.814 -23.001 -14.925 1.00 34.08 ? 403 SER D C 1 ATOM 4639 O O . SER D 1 183 ? -34.789 -23.725 -14.712 1.00 33.86 ? 403 SER D O 1 ATOM 4640 C CB . SER D 1 183 ? -31.918 -23.310 -16.502 1.00 32.33 ? 403 SER D CB 1 ATOM 4641 O OG . SER D 1 183 ? -32.832 -23.798 -17.474 1.00 29.31 ? 403 SER D OG 1 ATOM 4642 N N . PHE D 1 184 ? -33.898 -21.674 -15.038 1.00 32.21 ? 404 PHE D N 1 ATOM 4643 C CA . PHE D 1 184 ? -35.165 -20.969 -14.934 1.00 27.83 ? 404 PHE D CA 1 ATOM 4644 C C . PHE D 1 184 ? -35.682 -20.457 -16.287 1.00 30.81 ? 404 PHE D C 1 ATOM 4645 O O . PHE D 1 184 ? -34.921 -20.308 -17.233 1.00 29.00 ? 404 PHE D O 1 ATOM 4646 C CB . PHE D 1 184 ? -35.037 -19.807 -13.959 1.00 32.34 ? 404 PHE D CB 1 ATOM 4647 C CG . PHE D 1 184 ? -34.735 -20.222 -12.536 1.00 32.18 ? 404 PHE D CG 1 ATOM 4648 C CD1 . PHE D 1 184 ? -33.423 -20.440 -12.116 1.00 32.22 ? 404 PHE D CD1 1 ATOM 4649 C CD2 . PHE D 1 184 ? -35.758 -20.368 -11.609 1.00 28.00 ? 404 PHE D CD2 1 ATOM 4650 C CE1 . PHE D 1 184 ? -33.145 -20.796 -10.798 1.00 31.19 ? 404 PHE D CE1 1 ATOM 4651 C CE2 . PHE D 1 184 ? -35.485 -20.728 -10.291 1.00 28.80 ? 404 PHE D CE2 1 ATOM 4652 C CZ . PHE D 1 184 ? -34.180 -20.947 -9.889 1.00 29.55 ? 404 PHE D CZ 1 ATOM 4653 N N . PHE D 1 185 ? -36.990 -20.215 -16.372 1.00 27.67 ? 405 PHE D N 1 ATOM 4654 C CA . PHE D 1 185 ? -37.553 -19.441 -17.463 1.00 29.13 ? 405 PHE D CA 1 ATOM 4655 C C . PHE D 1 185 ? -38.606 -18.506 -16.916 1.00 36.01 ? 405 PHE D C 1 ATOM 4656 O O . PHE D 1 185 ? -39.203 -18.754 -15.853 1.00 33.16 ? 405 PHE D O 1 ATOM 4657 C CB . PHE D 1 185 ? -38.194 -20.332 -18.523 1.00 28.53 ? 405 PHE D CB 1 ATOM 4658 C CG . PHE D 1 185 ? -39.490 -20.948 -18.086 1.00 29.96 ? 405 PHE D CG 1 ATOM 4659 C CD1 . PHE D 1 185 ? -40.678 -20.235 -18.160 1.00 30.45 ? 405 PHE D CD1 1 ATOM 4660 C CD2 . PHE D 1 185 ? -39.517 -22.236 -17.586 1.00 33.05 ? 405 PHE D CD2 1 ATOM 4661 C CE1 . PHE D 1 185 ? -41.872 -20.802 -17.748 1.00 32.45 ? 405 PHE D CE1 1 ATOM 4662 C CE2 . PHE D 1 185 ? -40.706 -22.808 -17.170 1.00 34.82 ? 405 PHE D CE2 1 ATOM 4663 C CZ . PHE D 1 185 ? -41.885 -22.089 -17.254 1.00 35.21 ? 405 PHE D CZ 1 ATOM 4664 N N . LEU D 1 186 ? -38.841 -17.439 -17.668 1.00 33.66 ? 406 LEU D N 1 ATOM 4665 C CA . LEU D 1 186 ? -39.932 -16.534 -17.398 1.00 27.67 ? 406 LEU D CA 1 ATOM 4666 C C . LEU D 1 186 ? -40.536 -16.050 -18.710 1.00 29.53 ? 406 LEU D C 1 ATOM 4667 O O . LEU D 1 186 ? -40.014 -16.332 -19.787 1.00 31.07 ? 406 LEU D O 1 ATOM 4668 C CB . LEU D 1 186 ? -39.453 -15.367 -16.532 1.00 26.87 ? 406 LEU D CB 1 ATOM 4669 C CG . LEU D 1 186 ? -38.363 -14.372 -16.970 1.00 25.41 ? 406 LEU D CG 1 ATOM 4670 C CD1 . LEU D 1 186 ? -38.786 -13.523 -18.169 1.00 22.54 ? 406 LEU D CD1 1 ATOM 4671 C CD2 . LEU D 1 186 ? -38.067 -13.472 -15.778 1.00 25.04 ? 406 LEU D CD2 1 ATOM 4672 N N . ALA D 1 187 ? -41.654 -15.347 -18.609 1.00 31.64 ? 407 ALA D N 1 ATOM 4673 C CA . ALA D 1 187 ? -42.252 -14.672 -19.750 1.00 29.70 ? 407 ALA D CA 1 ATOM 4674 C C . ALA D 1 187 ? -42.594 -13.251 -19.327 1.00 31.07 ? 407 ALA D C 1 ATOM 4675 O O . ALA D 1 187 ? -42.942 -12.994 -18.171 1.00 30.73 ? 407 ALA D O 1 ATOM 4676 C CB . ALA D 1 187 ? -43.493 -15.411 -20.216 1.00 28.67 ? 407 ALA D CB 1 ATOM 4677 N N . SER D 1 188 ? -42.458 -12.317 -20.256 1.00 30.14 ? 408 SER D N 1 ATOM 4678 C CA . SER D 1 188 ? -42.836 -10.936 -19.992 1.00 23.99 ? 408 SER D CA 1 ATOM 4679 C C . SER D 1 188 ? -43.759 -10.519 -21.116 1.00 29.97 ? 408 SER D C 1 ATOM 4680 O O . SER D 1 188 ? -43.469 -10.778 -22.290 1.00 33.01 ? 408 SER D O 1 ATOM 4681 C CB . SER D 1 188 ? -41.604 -10.043 -19.935 1.00 17.83 ? 408 SER D CB 1 ATOM 4682 O OG . SER D 1 188 ? -41.985 -8.693 -19.917 1.00 20.37 ? 408 SER D OG 1 ATOM 4683 N N . LYS D 1 189 ? -44.872 -9.893 -20.747 1.00 31.37 ? 409 LYS D N 1 ATOM 4684 C CA . LYS D 1 189 ? -45.908 -9.490 -21.682 1.00 29.97 ? 409 LYS D CA 1 ATOM 4685 C C . LYS D 1 189 ? -45.988 -7.960 -21.727 1.00 36.04 ? 409 LYS D C 1 ATOM 4686 O O . LYS D 1 189 ? -46.124 -7.289 -20.689 1.00 23.73 ? 409 LYS D O 1 ATOM 4687 C CB . LYS D 1 189 ? -47.245 -10.106 -21.253 1.00 31.02 ? 409 LYS D CB 1 ATOM 4688 C CG . LYS D 1 189 ? -48.376 -9.997 -22.272 1.00 36.40 ? 409 LYS D CG 1 ATOM 4689 C CD . LYS D 1 189 ? -49.636 -10.792 -21.888 1.00 32.91 ? 409 LYS D CD 1 ATOM 4690 C CE . LYS D 1 189 ? -50.079 -10.594 -20.437 1.00 29.02 ? 409 LYS D CE 1 ATOM 4691 N NZ . LYS D 1 189 ? -50.851 -9.348 -20.205 1.00 31.34 ? 409 LYS D NZ 1 ATOM 4692 N N . LEU D 1 190 ? -45.851 -7.399 -22.923 1.00 27.22 ? 410 LEU D N 1 ATOM 4693 C CA . LEU D 1 190 ? -46.080 -5.967 -23.091 1.00 30.35 ? 410 LEU D CA 1 ATOM 4694 C C . LEU D 1 190 ? -47.401 -5.786 -23.808 1.00 35.25 ? 410 LEU D C 1 ATOM 4695 O O . LEU D 1 190 ? -47.666 -6.453 -24.825 1.00 28.33 ? 410 LEU D O 1 ATOM 4696 C CB . LEU D 1 190 ? -44.941 -5.269 -23.859 1.00 27.30 ? 410 LEU D CB 1 ATOM 4697 C CG . LEU D 1 190 ? -45.099 -3.753 -24.091 1.00 28.60 ? 410 LEU D CG 1 ATOM 4698 C CD1 . LEU D 1 190 ? -44.939 -2.963 -22.800 1.00 28.23 ? 410 LEU D CD1 1 ATOM 4699 C CD2 . LEU D 1 190 ? -44.123 -3.246 -25.137 1.00 31.63 ? 410 LEU D CD2 1 ATOM 4700 N N . THR D 1 191 ? -48.229 -4.894 -23.269 1.00 29.55 ? 411 THR D N 1 ATOM 4701 C CA . THR D 1 191 ? -49.545 -4.659 -23.821 1.00 32.11 ? 411 THR D CA 1 ATOM 4702 C C . THR D 1 191 ? -49.520 -3.324 -24.537 1.00 30.74 ? 411 THR D C 1 ATOM 4703 O O . THR D 1 191 ? -49.195 -2.308 -23.931 1.00 25.03 ? 411 THR D O 1 ATOM 4704 C CB . THR D 1 191 ? -50.622 -4.670 -22.718 1.00 31.21 ? 411 THR D CB 1 ATOM 4705 O OG1 . THR D 1 191 ? -50.565 -5.925 -22.032 1.00 28.99 ? 411 THR D OG1 1 ATOM 4706 C CG2 . THR D 1 191 ? -52.014 -4.466 -23.304 1.00 26.88 ? 411 THR D CG2 1 ATOM 4707 N N . VAL D 1 192 ? -49.839 -3.345 -25.835 1.00 25.99 ? 412 VAL D N 1 ATOM 4708 C CA . VAL D 1 192 ? -49.856 -2.128 -26.639 1.00 31.42 ? 412 VAL D CA 1 ATOM 4709 C C . VAL D 1 192 ? -51.121 -2.031 -27.483 1.00 34.59 ? 412 VAL D C 1 ATOM 4710 O O . VAL D 1 192 ? -51.657 -3.048 -27.926 1.00 39.55 ? 412 VAL D O 1 ATOM 4711 C CB . VAL D 1 192 ? -48.622 -2.013 -27.561 1.00 37.57 ? 412 VAL D CB 1 ATOM 4712 C CG1 . VAL D 1 192 ? -47.367 -1.750 -26.743 1.00 38.91 ? 412 VAL D CG1 1 ATOM 4713 C CG2 . VAL D 1 192 ? -48.461 -3.259 -28.426 1.00 35.55 ? 412 VAL D CG2 1 ATOM 4714 N N . ASP D 1 193 ? -51.586 -0.800 -27.689 1.00 31.68 ? 413 ASP D N 1 ATOM 4715 C CA . ASP D 1 193 ? -52.705 -0.520 -28.587 1.00 36.29 ? 413 ASP D CA 1 ATOM 4716 C C . ASP D 1 193 ? -52.421 -1.157 -29.927 1.00 32.57 ? 413 ASP D C 1 ATOM 4717 O O . ASP D 1 193 ? -51.306 -1.052 -30.441 1.00 28.11 ? 413 ASP D O 1 ATOM 4718 C CB . ASP D 1 193 ? -52.882 0.990 -28.783 1.00 43.25 ? 413 ASP D CB 1 ATOM 4719 C CG . ASP D 1 193 ? -53.280 1.711 -27.507 1.00 53.26 ? 413 ASP D CG 1 ATOM 4720 O OD1 . ASP D 1 193 ? -52.987 2.922 -27.406 1.00 58.18 ? 413 ASP D OD1 1 ATOM 4721 O OD2 . ASP D 1 193 ? -53.887 1.080 -26.609 1.00 57.59 ? 413 ASP D OD2 1 ATOM 4722 N N . LYS D 1 194 ? -53.419 -1.844 -30.466 1.00 37.51 ? 414 LYS D N 1 ATOM 4723 C CA . LYS D 1 194 ? -53.311 -2.506 -31.761 1.00 40.59 ? 414 LYS D CA 1 ATOM 4724 C C . LYS D 1 194 ? -52.771 -1.546 -32.824 1.00 37.59 ? 414 LYS D C 1 ATOM 4725 O O . LYS D 1 194 ? -52.026 -1.952 -33.720 1.00 45.28 ? 414 LYS D O 1 ATOM 4726 C CB . LYS D 1 194 ? -54.675 -3.094 -32.158 1.00 38.94 ? 414 LYS D CB 1 ATOM 4727 C CG . LYS D 1 194 ? -54.790 -3.611 -33.588 1.00 43.88 ? 414 LYS D CG 1 ATOM 4728 C CD . LYS D 1 194 ? -56.048 -4.451 -33.799 1.00 50.05 ? 414 LYS D CD 1 ATOM 4729 C CE . LYS D 1 194 ? -57.337 -3.651 -33.641 1.00 37.49 ? 414 LYS D CE 1 ATOM 4730 N N . SER D 1 195 ? -53.136 -0.274 -32.702 1.00 38.05 ? 415 SER D N 1 ATOM 4731 C CA . SER D 1 195 ? -52.698 0.763 -33.637 1.00 45.81 ? 415 SER D CA 1 ATOM 4732 C C . SER D 1 195 ? -51.170 0.949 -33.674 1.00 47.41 ? 415 SER D C 1 ATOM 4733 O O . SER D 1 195 ? -50.577 1.037 -34.762 1.00 33.69 ? 415 SER D O 1 ATOM 4734 C CB . SER D 1 195 ? -53.388 2.085 -33.316 1.00 41.08 ? 415 SER D CB 1 ATOM 4735 O OG . SER D 1 195 ? -53.080 2.489 -31.996 1.00 57.20 ? 415 SER D OG 1 ATOM 4736 N N . ARG D 1 196 ? -50.541 1.008 -32.495 1.00 34.87 ? 416 ARG D N 1 ATOM 4737 C CA . ARG D 1 196 ? -49.078 1.161 -32.399 1.00 36.91 ? 416 ARG D CA 1 ATOM 4738 C C . ARG D 1 196 ? -48.320 -0.023 -33.021 1.00 38.05 ? 416 ARG D C 1 ATOM 4739 O O . ARG D 1 196 ? -47.238 0.149 -33.583 1.00 44.03 ? 416 ARG D O 1 ATOM 4740 C CB . ARG D 1 196 ? -48.638 1.351 -30.937 1.00 35.74 ? 416 ARG D CB 1 ATOM 4741 C CG . ARG D 1 196 ? -49.212 2.589 -30.265 1.00 33.12 ? 416 ARG D CG 1 ATOM 4742 C CD . ARG D 1 196 ? -48.633 2.779 -28.878 1.00 36.78 ? 416 ARG D CD 1 ATOM 4743 N NE . ARG D 1 196 ? -47.181 2.925 -28.904 1.00 35.88 ? 416 ARG D NE 1 ATOM 4744 C CZ . ARG D 1 196 ? -46.382 2.684 -27.867 1.00 43.94 ? 416 ARG D CZ 1 ATOM 4745 N NH1 . ARG D 1 196 ? -46.886 2.277 -26.704 1.00 34.98 ? 416 ARG D NH1 1 ATOM 4746 N NH2 . ARG D 1 196 ? -45.072 2.851 -27.990 1.00 43.02 ? 416 ARG D NH2 1 ATOM 4747 N N . TRP D 1 197 ? -48.896 -1.218 -32.899 1.00 32.96 ? 417 TRP D N 1 ATOM 4748 C CA . TRP D 1 197 ? -48.347 -2.427 -33.492 1.00 33.66 ? 417 TRP D CA 1 ATOM 4749 C C . TRP D 1 197 ? -48.522 -2.443 -34.990 1.00 40.14 ? 417 TRP D C 1 ATOM 4750 O O . TRP D 1 197 ? -47.619 -2.853 -35.717 1.00 42.12 ? 417 TRP D O 1 ATOM 4751 C CB . TRP D 1 197 ? -49.009 -3.649 -32.869 1.00 30.28 ? 417 TRP D CB 1 ATOM 4752 C CG . TRP D 1 197 ? -48.510 -4.984 -33.389 1.00 29.04 ? 417 TRP D CG 1 ATOM 4753 C CD1 . TRP D 1 197 ? -49.243 -5.958 -34.058 1.00 30.90 ? 417 TRP D CD1 1 ATOM 4754 C CD2 . TRP D 1 197 ? -47.151 -5.548 -33.269 1.00 29.09 ? 417 TRP D CD2 1 ATOM 4755 N NE1 . TRP D 1 197 ? -48.460 -7.043 -34.366 1.00 36.13 ? 417 TRP D NE1 1 ATOM 4756 C CE2 . TRP D 1 197 ? -47.192 -6.857 -33.925 1.00 31.26 ? 417 TRP D CE2 1 ATOM 4757 C CE3 . TRP D 1 197 ? -45.950 -5.108 -32.707 1.00 29.51 ? 417 TRP D CE3 1 ATOM 4758 C CZ2 . TRP D 1 197 ? -46.073 -7.674 -34.006 1.00 33.25 ? 417 TRP D CZ2 1 ATOM 4759 C CZ3 . TRP D 1 197 ? -44.832 -5.941 -32.787 1.00 26.34 ? 417 TRP D CZ3 1 ATOM 4760 C CH2 . TRP D 1 197 ? -44.894 -7.195 -33.423 1.00 35.93 ? 417 TRP D CH2 1 ATOM 4761 N N . GLN D 1 198 ? -49.682 -1.985 -35.458 1.00 36.02 ? 418 GLN D N 1 ATOM 4762 C CA . GLN D 1 198 ? -50.066 -2.102 -36.868 1.00 41.72 ? 418 GLN D CA 1 ATOM 4763 C C . GLN D 1 198 ? -49.401 -1.011 -37.711 1.00 40.37 ? 418 GLN D C 1 ATOM 4764 O O . GLN D 1 198 ? -49.359 -1.084 -38.944 1.00 43.88 ? 418 GLN D O 1 ATOM 4765 C CB . GLN D 1 198 ? -51.597 -2.044 -36.990 1.00 37.14 ? 418 GLN D CB 1 ATOM 4766 C CG . GLN D 1 198 ? -52.180 -3.135 -37.870 1.00 48.62 ? 418 GLN D CG 1 ATOM 4767 C CD . GLN D 1 198 ? -53.566 -3.590 -37.432 1.00 63.08 ? 418 GLN D CD 1 ATOM 4768 O OE1 . GLN D 1 198 ? -53.918 -4.760 -37.596 1.00 71.73 ? 418 GLN D OE1 1 ATOM 4769 N NE2 . GLN D 1 198 ? -54.362 -2.671 -36.880 1.00 51.29 ? 418 GLN D NE2 1 ATOM 4770 N N . GLN D 1 199 ? -48.869 -0.016 -37.010 1.00 38.70 ? 419 GLN D N 1 ATOM 4771 C CA . GLN D 1 199 ? -48.262 1.178 -37.584 1.00 36.50 ? 419 GLN D CA 1 ATOM 4772 C C . GLN D 1 199 ? -46.758 0.962 -37.852 1.00 35.20 ? 419 GLN D C 1 ATOM 4773 O O . GLN D 1 199 ? -46.065 1.854 -38.357 1.00 36.69 ? 419 GLN D O 1 ATOM 4774 C CB . GLN D 1 199 ? -48.554 2.338 -36.616 1.00 41.05 ? 419 GLN D CB 1 ATOM 4775 C CG . GLN D 1 199 ? -47.820 3.656 -36.769 1.00 52.62 ? 419 GLN D CG 1 ATOM 4776 C CD . GLN D 1 199 ? -48.116 4.582 -35.594 1.00 62.17 ? 419 GLN D CD 1 ATOM 4777 O OE1 . GLN D 1 199 ? -47.203 5.109 -34.953 1.00 60.14 ? 419 GLN D OE1 1 ATOM 4778 N NE2 . GLN D 1 199 ? -49.399 4.760 -35.289 1.00 59.27 ? 419 GLN D NE2 1 ATOM 4779 N N . GLY D 1 200 ? -46.268 -0.233 -37.524 1.00 34.85 ? 420 GLY D N 1 ATOM 4780 C CA . GLY D 1 200 ? -44.913 -0.664 -37.893 1.00 35.50 ? 420 GLY D CA 1 ATOM 4781 C C . GLY D 1 200 ? -43.798 -0.481 -36.874 1.00 39.41 ? 420 GLY D C 1 ATOM 4782 O O . GLY D 1 200 ? -42.663 -0.907 -37.125 1.00 41.33 ? 420 GLY D O 1 ATOM 4783 N N . ASN D 1 201 ? -44.112 0.146 -35.736 1.00 29.89 ? 421 ASN D N 1 ATOM 4784 C CA . ASN D 1 201 ? -43.127 0.412 -34.679 1.00 32.97 ? 421 ASN D CA 1 ATOM 4785 C C . ASN D 1 201 ? -42.395 -0.820 -34.154 1.00 28.34 ? 421 ASN D C 1 ATOM 4786 O O . ASN D 1 201 ? -42.992 -1.872 -33.964 1.00 30.25 ? 421 ASN D O 1 ATOM 4787 C CB . ASN D 1 201 ? -43.785 1.090 -33.476 1.00 29.48 ? 421 ASN D CB 1 ATOM 4788 C CG . ASN D 1 201 ? -44.470 2.384 -33.831 1.00 28.95 ? 421 ASN D CG 1 ATOM 4789 O OD1 . ASN D 1 201 ? -43.824 3.369 -34.189 1.00 27.59 ? 421 ASN D OD1 1 ATOM 4790 N ND2 . ASN D 1 201 ? -45.794 2.402 -33.698 1.00 32.28 ? 421 ASN D ND2 1 ATOM 4791 N N . VAL D 1 202 ? -41.103 -0.655 -33.889 1.00 21.14 ? 422 VAL D N 1 ATOM 4792 C CA . VAL D 1 202 ? -40.281 -1.698 -33.327 1.00 22.45 ? 422 VAL D CA 1 ATOM 4793 C C . VAL D 1 202 ? -40.426 -1.689 -31.787 1.00 28.43 ? 422 VAL D C 1 ATOM 4794 O O . VAL D 1 202 ? -40.356 -0.638 -31.168 1.00 23.80 ? 422 VAL D O 1 ATOM 4795 C CB . VAL D 1 202 ? -38.806 -1.466 -33.732 1.00 23.31 ? 422 VAL D CB 1 ATOM 4796 C CG1 . VAL D 1 202 ? -37.884 -2.474 -33.066 1.00 19.76 ? 422 VAL D CG1 1 ATOM 4797 C CG2 . VAL D 1 202 ? -38.643 -1.515 -35.260 1.00 26.45 ? 422 VAL D CG2 1 ATOM 4798 N N . PHE D 1 203 ? -40.626 -2.855 -31.179 1.00 34.57 ? 423 PHE D N 1 ATOM 4799 C CA . PHE D 1 203 ? -40.586 -2.950 -29.705 1.00 33.68 ? 423 PHE D CA 1 ATOM 4800 C C . PHE D 1 203 ? -39.471 -3.882 -29.266 1.00 31.09 ? 423 PHE D C 1 ATOM 4801 O O . PHE D 1 203 ? -39.193 -4.885 -29.931 1.00 30.43 ? 423 PHE D O 1 ATOM 4802 C CB . PHE D 1 203 ? -41.937 -3.385 -29.141 1.00 31.83 ? 423 PHE D CB 1 ATOM 4803 C CG . PHE D 1 203 ? -43.026 -2.376 -29.368 1.00 32.66 ? 423 PHE D CG 1 ATOM 4804 C CD1 . PHE D 1 203 ? -43.766 -2.377 -30.556 1.00 30.68 ? 423 PHE D CD1 1 ATOM 4805 C CD2 . PHE D 1 203 ? -43.290 -1.402 -28.416 1.00 29.10 ? 423 PHE D CD2 1 ATOM 4806 C CE1 . PHE D 1 203 ? -44.758 -1.433 -30.765 1.00 30.68 ? 423 PHE D CE1 1 ATOM 4807 C CE2 . PHE D 1 203 ? -44.282 -0.454 -28.622 1.00 32.28 ? 423 PHE D CE2 1 ATOM 4808 C CZ . PHE D 1 203 ? -45.019 -0.470 -29.795 1.00 34.42 ? 423 PHE D CZ 1 ATOM 4809 N N . SER D 1 204 ? -38.821 -3.542 -28.159 1.00 27.52 ? 424 SER D N 1 ATOM 4810 C CA . SER D 1 204 ? -37.604 -4.233 -27.770 1.00 28.64 ? 424 SER D CA 1 ATOM 4811 C C . SER D 1 204 ? -37.642 -4.770 -26.351 1.00 29.23 ? 424 SER D C 1 ATOM 4812 O O . SER D 1 204 ? -37.973 -4.050 -25.406 1.00 22.08 ? 424 SER D O 1 ATOM 4813 C CB . SER D 1 204 ? -36.378 -3.322 -27.958 1.00 29.72 ? 424 SER D CB 1 ATOM 4814 O OG . SER D 1 204 ? -36.176 -3.031 -29.334 1.00 34.27 ? 424 SER D OG 1 ATOM 4815 N N . CYS D 1 205 ? -37.294 -6.047 -26.231 1.00 31.77 ? 425 CYS D N 1 ATOM 4816 C CA . CYS D 1 205 ? -37.163 -6.718 -24.948 1.00 38.12 ? 425 CYS D CA 1 ATOM 4817 C C . CYS D 1 205 ? -35.698 -6.702 -24.520 1.00 33.49 ? 425 CYS D C 1 ATOM 4818 O O . CYS D 1 205 ? -34.866 -7.346 -25.145 1.00 34.35 ? 425 CYS D O 1 ATOM 4819 C CB . CYS D 1 205 ? -37.630 -8.166 -25.072 1.00 37.86 ? 425 CYS D CB 1 ATOM 4820 S SG . CYS D 1 205 ? -37.564 -9.058 -23.515 1.00 52.33 ? 425 CYS D SG 1 ATOM 4821 N N . SER D 1 206 ? -35.403 -5.966 -23.458 1.00 25.46 ? 426 SER D N 1 ATOM 4822 C CA . SER D 1 206 ? -34.059 -5.877 -22.905 1.00 35.00 ? 426 SER D CA 1 ATOM 4823 C C . SER D 1 206 ? -33.927 -6.787 -21.693 1.00 35.58 ? 426 SER D C 1 ATOM 4824 O O . SER D 1 206 ? -34.683 -6.647 -20.721 1.00 36.49 ? 426 SER D O 1 ATOM 4825 C CB . SER D 1 206 ? -33.746 -4.438 -22.496 1.00 35.45 ? 426 SER D CB 1 ATOM 4826 O OG . SER D 1 206 ? -33.915 -3.566 -23.598 1.00 57.92 ? 426 SER D OG 1 ATOM 4827 N N . VAL D 1 207 ? -32.963 -7.708 -21.755 1.00 36.77 ? 427 VAL D N 1 ATOM 4828 C CA . VAL D 1 207 ? -32.702 -8.654 -20.665 1.00 33.91 ? 427 VAL D CA 1 ATOM 4829 C C . VAL D 1 207 ? -31.311 -8.401 -20.075 1.00 33.80 ? 427 VAL D C 1 ATOM 4830 O O . VAL D 1 207 ? -30.336 -8.199 -20.801 1.00 34.07 ? 427 VAL D O 1 ATOM 4831 C CB . VAL D 1 207 ? -32.852 -10.120 -21.141 1.00 33.82 ? 427 VAL D CB 1 ATOM 4832 C CG1 . VAL D 1 207 ? -32.540 -11.108 -20.025 1.00 40.58 ? 427 VAL D CG1 1 ATOM 4833 C CG2 . VAL D 1 207 ? -34.263 -10.371 -21.645 1.00 32.00 ? 427 VAL D CG2 1 ATOM 4834 N N . MET D 1 208 ? -31.239 -8.383 -18.750 1.00 35.60 ? 428 MET D N 1 ATOM 4835 C CA . MET D 1 208 ? -29.969 -8.309 -18.051 1.00 31.61 ? 428 MET D CA 1 ATOM 4836 C C . MET D 1 208 ? -29.790 -9.525 -17.158 1.00 35.50 ? 428 MET D C 1 ATOM 4837 O O . MET D 1 208 ? -30.689 -9.883 -16.393 1.00 29.20 ? 428 MET D O 1 ATOM 4838 C CB . MET D 1 208 ? -29.851 -7.019 -17.257 1.00 35.78 ? 428 MET D CB 1 ATOM 4839 C CG . MET D 1 208 ? -29.406 -5.848 -18.111 1.00 41.51 ? 428 MET D CG 1 ATOM 4840 S SD . MET D 1 208 ? -29.708 -4.250 -17.353 1.00 49.03 ? 428 MET D SD 1 ATOM 4841 C CE . MET D 1 208 ? -31.482 -4.078 -17.583 1.00 49.76 ? 428 MET D CE 1 ATOM 4842 N N . HIS D 1 209 ? -28.621 -10.152 -17.293 1.00 34.42 ? 429 HIS D N 1 ATOM 4843 C CA . HIS D 1 209 ? -28.254 -11.389 -16.602 1.00 37.49 ? 429 HIS D CA 1 ATOM 4844 C C . HIS D 1 209 ? -26.762 -11.562 -16.702 1.00 41.13 ? 429 HIS D C 1 ATOM 4845 O O . HIS D 1 209 ? -26.152 -11.229 -17.722 1.00 33.22 ? 429 HIS D O 1 ATOM 4846 C CB . HIS D 1 209 ? -28.955 -12.587 -17.237 1.00 34.97 ? 429 HIS D CB 1 ATOM 4847 C CG . HIS D 1 209 ? -28.793 -13.866 -16.462 1.00 35.42 ? 429 HIS D CG 1 ATOM 4848 N ND1 . HIS D 1 209 ? -27.752 -14.694 -16.648 1.00 30.70 ? 429 HIS D ND1 1 ATOM 4849 C CD2 . HIS D 1 209 ? -29.584 -14.440 -15.460 1.00 28.84 ? 429 HIS D CD2 1 ATOM 4850 C CE1 . HIS D 1 209 ? -27.867 -15.751 -15.822 1.00 26.91 ? 429 HIS D CE1 1 ATOM 4851 N NE2 . HIS D 1 209 ? -28.990 -15.592 -15.095 1.00 27.18 ? 429 HIS D NE2 1 ATOM 4852 N N . GLU D 1 210 ? -26.157 -12.113 -15.660 1.00 43.65 ? 430 GLU D N 1 ATOM 4853 C CA . GLU D 1 210 ? -24.697 -12.224 -15.593 1.00 37.81 ? 430 GLU D CA 1 ATOM 4854 C C . GLU D 1 210 ? -24.048 -13.079 -16.671 1.00 32.46 ? 430 GLU D C 1 ATOM 4855 O O . GLU D 1 210 ? -22.905 -12.850 -17.031 1.00 41.51 ? 430 GLU D O 1 ATOM 4856 C CB . GLU D 1 210 ? -24.268 -12.750 -14.232 1.00 34.96 ? 430 GLU D CB 1 ATOM 4857 C CG . GLU D 1 210 ? -24.671 -14.183 -13.960 1.00 33.47 ? 430 GLU D CG 1 ATOM 4858 C CD . GLU D 1 210 ? -24.006 -14.703 -12.704 1.00 50.27 ? 430 GLU D CD 1 ATOM 4859 O OE1 . GLU D 1 210 ? -24.721 -14.938 -11.706 1.00 42.05 ? 430 GLU D OE1 1 ATOM 4860 O OE2 . GLU D 1 210 ? -22.763 -14.844 -12.711 1.00 53.71 ? 430 GLU D OE2 1 ATOM 4861 N N . ALA D 1 211 ? -24.759 -14.081 -17.160 1.00 29.71 ? 431 ALA D N 1 ATOM 4862 C CA . ALA D 1 211 ? -24.164 -15.021 -18.088 1.00 32.48 ? 431 ALA D CA 1 ATOM 4863 C C . ALA D 1 211 ? -24.345 -14.572 -19.544 1.00 28.45 ? 431 ALA D C 1 ATOM 4864 O O . ALA D 1 211 ? -24.035 -15.315 -20.478 1.00 36.29 ? 431 ALA D O 1 ATOM 4865 C CB . ALA D 1 211 ? -24.722 -16.414 -17.856 1.00 31.50 ? 431 ALA D CB 1 ATOM 4866 N N . LEU D 1 212 ? -24.856 -13.357 -19.717 1.00 24.51 ? 432 LEU D N 1 ATOM 4867 C CA . LEU D 1 212 ? -24.961 -12.729 -21.017 1.00 30.13 ? 432 LEU D CA 1 ATOM 4868 C C . LEU D 1 212 ? -23.703 -11.937 -21.245 1.00 34.67 ? 432 LEU D C 1 ATOM 4869 O O . LEU D 1 212 ? -23.113 -11.399 -20.302 1.00 31.91 ? 432 LEU D O 1 ATOM 4870 C CB . LEU D 1 212 ? -26.157 -11.772 -21.081 1.00 24.94 ? 432 LEU D CB 1 ATOM 4871 C CG . LEU D 1 212 ? -27.547 -12.375 -21.270 1.00 27.24 ? 432 LEU D CG 1 ATOM 4872 C CD1 . LEU D 1 212 ? -28.612 -11.313 -21.036 1.00 23.83 ? 432 LEU D CD1 1 ATOM 4873 C CD2 . LEU D 1 212 ? -27.691 -13.028 -22.642 1.00 25.70 ? 432 LEU D CD2 1 ATOM 4874 N N . HIS D 1 213 ? -23.288 -11.872 -22.503 1.00 37.05 ? 433 HIS D N 1 ATOM 4875 C CA . HIS D 1 213 ? -22.224 -10.962 -22.895 1.00 41.32 ? 433 HIS D CA 1 ATOM 4876 C C . HIS D 1 213 ? -22.512 -9.573 -22.357 1.00 33.39 ? 433 HIS D C 1 ATOM 4877 O O . HIS D 1 213 ? -23.604 -9.030 -22.532 1.00 31.04 ? 433 HIS D O 1 ATOM 4878 C CB . HIS D 1 213 ? -22.066 -10.963 -24.411 1.00 38.41 ? 433 HIS D CB 1 ATOM 4879 C CG . HIS D 1 213 ? -20.859 -10.198 -24.887 1.00 42.52 ? 433 HIS D CG 1 ATOM 4880 N ND1 . HIS D 1 213 ? -19.603 -10.662 -24.737 1.00 39.28 ? 433 HIS D ND1 1 ATOM 4881 C CD2 . HIS D 1 213 ? -20.751 -8.955 -25.507 1.00 39.62 ? 433 HIS D CD2 1 ATOM 4882 C CE1 . HIS D 1 213 ? -18.735 -9.766 -25.235 1.00 38.83 ? 433 HIS D CE1 1 ATOM 4883 N NE2 . HIS D 1 213 ? -19.441 -8.722 -25.709 1.00 40.68 ? 433 HIS D NE2 1 ATOM 4884 N N . ASN D 1 214 ? -21.552 -9.004 -21.640 1.00 35.75 ? 434 ASN D N 1 ATOM 4885 C CA . ASN D 1 214 ? -21.752 -7.696 -21.005 1.00 35.23 ? 434 ASN D CA 1 ATOM 4886 C C . ASN D 1 214 ? -23.052 -7.547 -20.199 1.00 32.46 ? 434 ASN D C 1 ATOM 4887 O O . ASN D 1 214 ? -23.566 -6.431 -19.994 1.00 27.73 ? 434 ASN D O 1 ATOM 4888 C CB . ASN D 1 214 ? -21.603 -6.589 -22.043 1.00 41.52 ? 434 ASN D CB 1 ATOM 4889 C CG . ASN D 1 214 ? -20.164 -6.384 -22.434 1.00 46.33 ? 434 ASN D CG 1 ATOM 4890 O OD1 . ASN D 1 214 ? -19.263 -6.526 -21.595 1.00 41.77 ? 434 ASN D OD1 1 ATOM 4891 N ND2 . ASN D 1 214 ? -19.927 -6.076 -23.701 1.00 37.93 ? 434 ASN D ND2 1 ATOM 4892 N N . HIS D 1 215 ? -23.553 -8.686 -19.726 1.00 24.33 ? 435 HIS D N 1 ATOM 4893 C CA . HIS D 1 215 ? -24.749 -8.743 -18.896 1.00 29.83 ? 435 HIS D CA 1 ATOM 4894 C C . HIS D 1 215 ? -25.985 -8.218 -19.556 1.00 32.36 ? 435 HIS D C 1 ATOM 4895 O O . HIS D 1 215 ? -26.884 -7.751 -18.860 1.00 26.80 ? 435 HIS D O 1 ATOM 4896 C CB . HIS D 1 215 ? -24.553 -7.982 -17.577 1.00 28.94 ? 435 HIS D CB 1 ATOM 4897 C CG . HIS D 1 215 ? -23.409 -8.477 -16.734 1.00 27.47 ? 435 HIS D CG 1 ATOM 4898 N ND1 . HIS D 1 215 ? -23.005 -7.829 -15.629 1.00 33.55 ? 435 HIS D ND1 1 ATOM 4899 C CD2 . HIS D 1 215 ? -22.588 -9.598 -16.854 1.00 32.28 ? 435 HIS D CD2 1 ATOM 4900 C CE1 . HIS D 1 215 ? -21.983 -8.500 -15.063 1.00 32.79 ? 435 HIS D CE1 1 ATOM 4901 N NE2 . HIS D 1 215 ? -21.724 -9.576 -15.817 1.00 33.83 ? 435 HIS D NE2 1 ATOM 4902 N N . TYR D 1 216 ? -26.064 -8.299 -20.886 1.00 28.60 ? 436 TYR D N 1 ATOM 4903 C CA . TYR D 1 216 ? -27.108 -7.583 -21.611 1.00 26.88 ? 436 TYR D CA 1 ATOM 4904 C C . TYR D 1 216 ? -27.356 -8.194 -22.968 1.00 28.76 ? 436 TYR D C 1 ATOM 4905 O O . TYR D 1 216 ? -26.418 -8.567 -23.658 1.00 26.74 ? 436 TYR D O 1 ATOM 4906 C CB . TYR D 1 216 ? -26.718 -6.108 -21.780 1.00 29.45 ? 436 TYR D CB 1 ATOM 4907 C CG . TYR D 1 216 ? -27.774 -5.232 -22.441 1.00 31.81 ? 436 TYR D CG 1 ATOM 4908 C CD1 . TYR D 1 216 ? -27.802 -5.074 -23.830 1.00 34.26 ? 436 TYR D CD1 1 ATOM 4909 C CD2 . TYR D 1 216 ? -28.734 -4.556 -21.682 1.00 29.99 ? 436 TYR D CD2 1 ATOM 4910 C CE1 . TYR D 1 216 ? -28.759 -4.282 -24.446 1.00 34.86 ? 436 TYR D CE1 1 ATOM 4911 C CE2 . TYR D 1 216 ? -29.695 -3.752 -22.288 1.00 34.92 ? 436 TYR D CE2 1 ATOM 4912 C CZ . TYR D 1 216 ? -29.698 -3.620 -23.675 1.00 40.15 ? 436 TYR D CZ 1 ATOM 4913 O OH . TYR D 1 216 ? -30.636 -2.831 -24.305 1.00 50.20 ? 436 TYR D OH 1 ATOM 4914 N N . THR D 1 217 ? -28.636 -8.336 -23.314 1.00 32.48 ? 437 THR D N 1 ATOM 4915 C CA . THR D 1 217 ? -29.062 -8.607 -24.692 1.00 33.32 ? 437 THR D CA 1 ATOM 4916 C C . THR D 1 217 ? -30.400 -7.912 -24.913 1.00 34.96 ? 437 THR D C 1 ATOM 4917 O O . THR D 1 217 ? -31.070 -7.503 -23.959 1.00 27.38 ? 437 THR D O 1 ATOM 4918 C CB . THR D 1 217 ? -29.142 -10.114 -25.041 1.00 35.99 ? 437 THR D CB 1 ATOM 4919 O OG1 . THR D 1 217 ? -29.302 -10.270 -26.458 1.00 37.72 ? 437 THR D OG1 1 ATOM 4920 C CG2 . THR D 1 217 ? -30.318 -10.790 -24.347 1.00 34.54 ? 437 THR D CG2 1 ATOM 4921 N N . GLN D 1 218 ? -30.765 -7.760 -26.178 1.00 30.57 ? 438 GLN D N 1 ATOM 4922 C CA . GLN D 1 218 ? -31.972 -7.067 -26.556 1.00 29.74 ? 438 GLN D CA 1 ATOM 4923 C C . GLN D 1 218 ? -32.517 -7.774 -27.780 1.00 32.00 ? 438 GLN D C 1 ATOM 4924 O O . GLN D 1 218 ? -31.750 -8.094 -28.670 1.00 27.55 ? 438 GLN D O 1 ATOM 4925 C CB . GLN D 1 218 ? -31.646 -5.618 -26.899 1.00 33.25 ? 438 GLN D CB 1 ATOM 4926 C CG . GLN D 1 218 ? -32.860 -4.770 -27.203 1.00 37.38 ? 438 GLN D CG 1 ATOM 4927 C CD . GLN D 1 218 ? -32.483 -3.364 -27.584 1.00 47.87 ? 438 GLN D CD 1 ATOM 4928 O OE1 . GLN D 1 218 ? -32.484 -2.456 -26.743 1.00 47.90 ? 438 GLN D OE1 1 ATOM 4929 N NE2 . GLN D 1 218 ? -32.132 -3.172 -28.852 1.00 51.29 ? 438 GLN D NE2 1 ATOM 4930 N N . LYS D 1 219 ? -33.823 -8.046 -27.791 1.00 34.30 ? 439 LYS D N 1 ATOM 4931 C CA . LYS D 1 219 ? -34.508 -8.623 -28.953 1.00 35.33 ? 439 LYS D CA 1 ATOM 4932 C C . LYS D 1 219 ? -35.681 -7.737 -29.317 1.00 34.89 ? 439 LYS D C 1 ATOM 4933 O O . LYS D 1 219 ? -36.352 -7.184 -28.440 1.00 34.57 ? 439 LYS D O 1 ATOM 4934 C CB . LYS D 1 219 ? -34.992 -10.053 -28.684 1.00 30.51 ? 439 LYS D CB 1 ATOM 4935 C CG . LYS D 1 219 ? -33.909 -11.034 -28.259 1.00 36.05 ? 439 LYS D CG 1 ATOM 4936 C CD . LYS D 1 219 ? -32.966 -11.405 -29.392 1.00 40.82 ? 439 LYS D CD 1 ATOM 4937 C CE . LYS D 1 219 ? -31.884 -12.351 -28.895 1.00 45.69 ? 439 LYS D CE 1 ATOM 4938 N NZ . LYS D 1 219 ? -30.760 -12.495 -29.859 1.00 48.04 ? 439 LYS D NZ 1 ATOM 4939 N N . SER D 1 220 ? -35.915 -7.608 -30.620 1.00 36.30 ? 440 SER D N 1 ATOM 4940 C CA . SER D 1 220 ? -36.910 -6.691 -31.147 1.00 31.68 ? 440 SER D CA 1 ATOM 4941 C C . SER D 1 220 ? -37.904 -7.396 -32.040 1.00 36.43 ? 440 SER D C 1 ATOM 4942 O O . SER D 1 220 ? -37.583 -8.401 -32.680 1.00 34.03 ? 440 SER D O 1 ATOM 4943 C CB . SER D 1 220 ? -36.238 -5.586 -31.962 1.00 29.92 ? 440 SER D CB 1 ATOM 4944 O OG . SER D 1 220 ? -35.556 -4.664 -31.143 1.00 30.96 ? 440 SER D OG 1 ATOM 4945 N N . LEU D 1 221 ? -39.109 -6.841 -32.095 1.00 33.11 ? 441 LEU D N 1 ATOM 4946 C CA . LEU D 1 221 ? -40.125 -7.313 -33.007 1.00 33.90 ? 441 LEU D CA 1 ATOM 4947 C C . LEU D 1 221 ? -40.960 -6.138 -33.500 1.00 37.31 ? 441 LEU D C 1 ATOM 4948 O O . LEU D 1 221 ? -41.047 -5.103 -32.831 1.00 37.28 ? 441 LEU D O 1 ATOM 4949 C CB . LEU D 1 221 ? -40.974 -8.416 -32.357 1.00 34.40 ? 441 LEU D CB 1 ATOM 4950 C CG . LEU D 1 221 ? -42.105 -8.163 -31.350 1.00 34.54 ? 441 LEU D CG 1 ATOM 4951 C CD1 . LEU D 1 221 ? -42.786 -9.487 -31.057 1.00 27.99 ? 441 LEU D CD1 1 ATOM 4952 C CD2 . LEU D 1 221 ? -41.649 -7.488 -30.058 1.00 32.36 ? 441 LEU D CD2 1 ATOM 4953 N N . SER D 1 222 ? -41.509 -6.289 -34.703 1.00 35.34 ? 442 SER D N 1 ATOM 4954 C CA . SER D 1 222 ? -42.398 -5.303 -35.308 1.00 37.53 ? 442 SER D CA 1 ATOM 4955 C C . SER D 1 222 ? -43.440 -6.040 -36.149 1.00 30.65 ? 442 SER D C 1 ATOM 4956 O O . SER D 1 222 ? -43.343 -7.244 -36.315 1.00 35.01 ? 442 SER D O 1 ATOM 4957 C CB . SER D 1 222 ? -41.607 -4.314 -36.171 1.00 31.57 ? 442 SER D CB 1 ATOM 4958 O OG . SER D 1 222 ? -41.094 -4.962 -37.315 1.00 40.20 ? 442 SER D OG 1 ATOM 4959 N N . LEU D 1 223 ? -44.427 -5.319 -36.677 1.00 37.94 ? 443 LEU D N 1 ATOM 4960 C CA . LEU D 1 223 ? -45.465 -5.924 -37.525 1.00 45.59 ? 443 LEU D CA 1 ATOM 4961 C C . LEU D 1 223 ? -44.917 -6.994 -38.467 1.00 44.22 ? 443 LEU D C 1 ATOM 4962 O O . LEU D 1 223 ? -44.115 -6.705 -39.354 1.00 46.36 ? 443 LEU D O 1 ATOM 4963 C CB . LEU D 1 223 ? -46.198 -4.855 -38.333 1.00 47.43 ? 443 LEU D CB 1 ATOM 4964 C CG . LEU D 1 223 ? -47.421 -5.315 -39.139 1.00 51.28 ? 443 LEU D CG 1 ATOM 4965 C CD1 . LEU D 1 223 ? -48.547 -5.807 -38.237 1.00 46.66 ? 443 LEU D CD1 1 ATOM 4966 C CD2 . LEU D 1 223 ? -47.904 -4.196 -40.054 1.00 56.03 ? 443 LEU D CD2 1 ATOM 4967 N N . GLY E 2 30 ? -52.780 -23.150 23.291 1.00 68.42 ? 237 GLY E N 1 ATOM 4968 C CA . GLY E 2 30 ? -53.971 -23.857 22.734 1.00 77.22 ? 237 GLY E CA 1 ATOM 4969 C C . GLY E 2 30 ? -53.839 -24.196 21.257 1.00 70.31 ? 237 GLY E C 1 ATOM 4970 O O . GLY E 2 30 ? -52.887 -23.763 20.604 1.00 77.10 ? 237 GLY E O 1 ATOM 4971 N N . PRO E 2 31 ? -54.795 -24.980 20.721 1.00 65.76 ? 238 PRO E N 1 ATOM 4972 C CA . PRO E 2 31 ? -54.823 -25.393 19.307 1.00 64.69 ? 238 PRO E CA 1 ATOM 4973 C C . PRO E 2 31 ? -55.103 -24.267 18.298 1.00 61.74 ? 238 PRO E C 1 ATOM 4974 O O . PRO E 2 31 ? -55.708 -23.253 18.647 1.00 67.49 ? 238 PRO E O 1 ATOM 4975 C CB . PRO E 2 31 ? -55.954 -26.431 19.261 1.00 64.07 ? 238 PRO E CB 1 ATOM 4976 C CG . PRO E 2 31 ? -56.787 -26.160 20.463 1.00 63.73 ? 238 PRO E CG 1 ATOM 4977 C CD . PRO E 2 31 ? -55.833 -25.665 21.510 1.00 64.05 ? 238 PRO E CD 1 ATOM 4978 N N . SER E 2 32 ? -54.670 -24.475 17.054 1.00 60.41 ? 239 SER E N 1 ATOM 4979 C CA . SER E 2 32 ? -54.833 -23.504 15.968 1.00 55.03 ? 239 SER E CA 1 ATOM 4980 C C . SER E 2 32 ? -55.621 -24.091 14.811 1.00 55.73 ? 239 SER E C 1 ATOM 4981 O O . SER E 2 32 ? -55.455 -25.266 14.468 1.00 51.27 ? 239 SER E O 1 ATOM 4982 C CB . SER E 2 32 ? -53.471 -23.039 15.451 1.00 52.66 ? 239 SER E CB 1 ATOM 4983 O OG . SER E 2 32 ? -52.814 -22.229 16.408 1.00 64.17 ? 239 SER E OG 1 ATOM 4984 N N . VAL E 2 33 ? -56.454 -23.253 14.197 1.00 47.90 ? 240 VAL E N 1 ATOM 4985 C CA . VAL E 2 33 ? -57.325 -23.666 13.096 1.00 47.17 ? 240 VAL E CA 1 ATOM 4986 C C . VAL E 2 33 ? -56.855 -23.103 11.750 1.00 46.49 ? 240 VAL E C 1 ATOM 4987 O O . VAL E 2 33 ? -56.427 -21.949 11.660 1.00 45.48 ? 240 VAL E O 1 ATOM 4988 C CB . VAL E 2 33 ? -58.787 -23.219 13.346 1.00 46.49 ? 240 VAL E CB 1 ATOM 4989 C CG1 . VAL E 2 33 ? -59.724 -23.768 12.275 1.00 47.05 ? 240 VAL E CG1 1 ATOM 4990 C CG2 . VAL E 2 33 ? -59.257 -23.633 14.736 1.00 44.81 ? 240 VAL E CG2 1 ATOM 4991 N N . PHE E 2 34 ? -56.936 -23.933 10.712 1.00 44.67 ? 241 PHE E N 1 ATOM 4992 C CA . PHE E 2 34 ? -56.751 -23.493 9.330 1.00 46.62 ? 241 PHE E CA 1 ATOM 4993 C C . PHE E 2 34 ? -57.832 -24.115 8.451 1.00 47.58 ? 241 PHE E C 1 ATOM 4994 O O . PHE E 2 34 ? -58.146 -25.297 8.589 1.00 52.36 ? 241 PHE E O 1 ATOM 4995 C CB . PHE E 2 34 ? -55.363 -23.870 8.813 1.00 45.99 ? 241 PHE E CB 1 ATOM 4996 C CG . PHE E 2 34 ? -54.240 -23.287 9.619 1.00 55.14 ? 241 PHE E CG 1 ATOM 4997 C CD1 . PHE E 2 34 ? -53.891 -21.943 9.486 1.00 57.47 ? 241 PHE E CD1 1 ATOM 4998 C CD2 . PHE E 2 34 ? -53.533 -24.077 10.521 1.00 55.75 ? 241 PHE E CD2 1 ATOM 4999 C CE1 . PHE E 2 34 ? -52.859 -21.402 10.238 1.00 67.00 ? 241 PHE E CE1 1 ATOM 5000 C CE2 . PHE E 2 34 ? -52.498 -23.541 11.274 1.00 58.59 ? 241 PHE E CE2 1 ATOM 5001 C CZ . PHE E 2 34 ? -52.161 -22.203 11.132 1.00 64.72 ? 241 PHE E CZ 1 ATOM 5002 N N . LEU E 2 35 ? -58.397 -23.311 7.552 1.00 41.54 ? 242 LEU E N 1 ATOM 5003 C CA . LEU E 2 35 ? -59.492 -23.742 6.695 1.00 40.18 ? 242 LEU E CA 1 ATOM 5004 C C . LEU E 2 35 ? -59.094 -23.655 5.224 1.00 38.65 ? 242 LEU E C 1 ATOM 5005 O O . LEU E 2 35 ? -58.613 -22.622 4.768 1.00 39.75 ? 242 LEU E O 1 ATOM 5006 C CB . LEU E 2 35 ? -60.728 -22.880 6.970 1.00 37.26 ? 242 LEU E CB 1 ATOM 5007 C CG . LEU E 2 35 ? -62.069 -23.273 6.344 1.00 38.26 ? 242 LEU E CG 1 ATOM 5008 C CD1 . LEU E 2 35 ? -62.465 -24.701 6.698 1.00 37.76 ? 242 LEU E CD1 1 ATOM 5009 C CD2 . LEU E 2 35 ? -63.153 -22.294 6.773 1.00 34.10 ? 242 LEU E CD2 1 ATOM 5010 N N . PHE E 2 36 ? -59.330 -24.730 4.482 1.00 37.73 ? 243 PHE E N 1 ATOM 5011 C CA . PHE E 2 36 ? -58.802 -24.849 3.130 1.00 35.13 ? 243 PHE E CA 1 ATOM 5012 C C . PHE E 2 36 ? -59.883 -25.017 2.075 1.00 38.66 ? 243 PHE E C 1 ATOM 5013 O O . PHE E 2 36 ? -60.898 -25.677 2.321 1.00 38.30 ? 243 PHE E O 1 ATOM 5014 C CB . PHE E 2 36 ? -57.803 -26.011 3.055 1.00 36.59 ? 243 PHE E CB 1 ATOM 5015 C CG . PHE E 2 36 ? -56.582 -25.810 3.898 1.00 48.89 ? 243 PHE E CG 1 ATOM 5016 C CD1 . PHE E 2 36 ? -55.468 -25.146 3.384 1.00 53.14 ? 243 PHE E CD1 1 ATOM 5017 C CD2 . PHE E 2 36 ? -56.541 -26.276 5.213 1.00 48.01 ? 243 PHE E CD2 1 ATOM 5018 C CE1 . PHE E 2 36 ? -54.340 -24.955 4.166 1.00 59.89 ? 243 PHE E CE1 1 ATOM 5019 C CE2 . PHE E 2 36 ? -55.415 -26.084 5.998 1.00 49.77 ? 243 PHE E CE2 1 ATOM 5020 C CZ . PHE E 2 36 ? -54.312 -25.425 5.474 1.00 52.35 ? 243 PHE E CZ 1 ATOM 5021 N N . PRO E 2 37 ? -59.657 -24.436 0.881 1.00 36.60 ? 244 PRO E N 1 ATOM 5022 C CA . PRO E 2 37 ? -60.666 -24.482 -0.158 1.00 35.71 ? 244 PRO E CA 1 ATOM 5023 C C . PRO E 2 37 ? -60.530 -25.743 -1.022 1.00 37.33 ? 244 PRO E C 1 ATOM 5024 O O . PRO E 2 37 ? -59.535 -26.455 -0.913 1.00 47.61 ? 244 PRO E O 1 ATOM 5025 C CB . PRO E 2 37 ? -60.379 -23.205 -0.955 1.00 30.53 ? 244 PRO E CB 1 ATOM 5026 C CG . PRO E 2 37 ? -58.900 -23.034 -0.851 1.00 28.50 ? 244 PRO E CG 1 ATOM 5027 C CD . PRO E 2 37 ? -58.492 -23.624 0.474 1.00 36.43 ? 244 PRO E CD 1 ATOM 5028 N N . PRO E 2 38 ? -61.539 -26.041 -1.858 1.00 43.73 ? 245 PRO E N 1 ATOM 5029 C CA . PRO E 2 38 ? -61.390 -27.190 -2.756 1.00 43.48 ? 245 PRO E CA 1 ATOM 5030 C C . PRO E 2 38 ? -60.333 -26.950 -3.834 1.00 40.78 ? 245 PRO E C 1 ATOM 5031 O O . PRO E 2 38 ? -60.024 -25.802 -4.144 1.00 39.14 ? 245 PRO E O 1 ATOM 5032 C CB . PRO E 2 38 ? -62.781 -27.329 -3.383 1.00 36.34 ? 245 PRO E CB 1 ATOM 5033 C CG . PRO E 2 38 ? -63.383 -25.971 -3.260 1.00 37.86 ? 245 PRO E CG 1 ATOM 5034 C CD . PRO E 2 38 ? -62.870 -25.418 -1.968 1.00 40.47 ? 245 PRO E CD 1 ATOM 5035 N N . LYS E 2 39 ? -59.761 -28.022 -4.374 1.00 42.46 ? 246 LYS E N 1 ATOM 5036 C CA . LYS E 2 39 ? -58.925 -27.899 -5.560 1.00 52.69 ? 246 LYS E CA 1 ATOM 5037 C C . LYS E 2 39 ? -59.761 -27.247 -6.656 1.00 47.57 ? 246 LYS E C 1 ATOM 5038 O O . LYS E 2 39 ? -60.945 -27.546 -6.783 1.00 43.43 ? 246 LYS E O 1 ATOM 5039 C CB . LYS E 2 39 ? -58.421 -29.264 -6.041 1.00 60.45 ? 246 LYS E CB 1 ATOM 5040 C CG . LYS E 2 39 ? -57.471 -29.983 -5.095 1.00 65.11 ? 246 LYS E CG 1 ATOM 5041 C CD . LYS E 2 39 ? -56.075 -29.372 -5.072 1.00 63.85 ? 246 LYS E CD 1 ATOM 5042 C CE . LYS E 2 39 ? -55.302 -29.827 -3.840 1.00 58.60 ? 246 LYS E CE 1 ATOM 5043 N NZ . LYS E 2 39 ? -55.920 -29.331 -2.575 1.00 50.56 ? 246 LYS E NZ 1 ATOM 5044 N N . PRO E 2 40 ? -59.161 -26.313 -7.413 1.00 47.39 ? 247 PRO E N 1 ATOM 5045 C CA . PRO E 2 40 ? -59.845 -25.702 -8.548 1.00 55.73 ? 247 PRO E CA 1 ATOM 5046 C C . PRO E 2 40 ? -60.473 -26.726 -9.491 1.00 48.25 ? 247 PRO E C 1 ATOM 5047 O O . PRO E 2 40 ? -61.651 -26.616 -9.817 1.00 54.27 ? 247 PRO E O 1 ATOM 5048 C CB . PRO E 2 40 ? -58.722 -24.936 -9.243 1.00 48.82 ? 247 PRO E CB 1 ATOM 5049 C CG . PRO E 2 40 ? -57.877 -24.478 -8.099 1.00 52.05 ? 247 PRO E CG 1 ATOM 5050 C CD . PRO E 2 40 ? -57.905 -25.604 -7.093 1.00 45.93 ? 247 PRO E CD 1 ATOM 5051 N N . LYS E 2 41 ? -59.694 -27.722 -9.889 1.00 49.88 ? 248 LYS E N 1 ATOM 5052 C CA . LYS E 2 41 ? -60.145 -28.758 -10.817 1.00 52.93 ? 248 LYS E CA 1 ATOM 5053 C C . LYS E 2 41 ? -61.380 -29.508 -10.312 1.00 47.07 ? 248 LYS E C 1 ATOM 5054 O O . LYS E 2 41 ? -62.212 -29.932 -11.116 1.00 36.15 ? 248 LYS E O 1 ATOM 5055 C CB . LYS E 2 41 ? -59.005 -29.741 -11.099 1.00 57.53 ? 248 LYS E CB 1 ATOM 5056 C CG . LYS E 2 41 ? -59.071 -30.372 -12.478 1.00 63.90 ? 248 LYS E CG 1 ATOM 5057 C CD . LYS E 2 41 ? -57.760 -31.036 -12.853 1.00 67.38 ? 248 LYS E CD 1 ATOM 5058 C CE . LYS E 2 41 ? -57.827 -31.591 -14.264 1.00 59.83 ? 248 LYS E CE 1 ATOM 5059 N NZ . LYS E 2 41 ? -56.605 -32.365 -14.606 1.00 68.27 ? 248 LYS E NZ 1 ATOM 5060 N N . ASP E 2 42 ? -61.482 -29.661 -8.987 1.00 40.15 ? 249 ASP E N 1 ATOM 5061 C CA . ASP E 2 42 ? -62.623 -30.307 -8.336 1.00 40.01 ? 249 ASP E CA 1 ATOM 5062 C C . ASP E 2 42 ? -63.935 -29.546 -8.556 1.00 37.31 ? 249 ASP E C 1 ATOM 5063 O O . ASP E 2 42 ? -64.979 -30.160 -8.783 1.00 40.84 ? 249 ASP E O 1 ATOM 5064 C CB . ASP E 2 42 ? -62.372 -30.463 -6.825 1.00 43.94 ? 249 ASP E CB 1 ATOM 5065 C CG . ASP E 2 42 ? -61.260 -31.467 -6.494 1.00 55.40 ? 249 ASP E CG 1 ATOM 5066 O OD1 . ASP E 2 42 ? -60.895 -32.308 -7.351 1.00 39.44 ? 249 ASP E OD1 1 ATOM 5067 O OD2 . ASP E 2 42 ? -60.760 -31.418 -5.345 1.00 62.15 ? 249 ASP E OD2 1 ATOM 5068 N N . THR E 2 43 ? -63.873 -28.215 -8.487 1.00 33.67 ? 250 THR E N 1 ATOM 5069 C CA . THR E 2 43 ? -65.045 -27.369 -8.685 1.00 37.45 ? 250 THR E CA 1 ATOM 5070 C C . THR E 2 43 ? -65.453 -27.239 -10.166 1.00 39.60 ? 250 THR E C 1 ATOM 5071 O O . THR E 2 43 ? -66.598 -26.895 -10.465 1.00 39.25 ? 250 THR E O 1 ATOM 5072 C CB . THR E 2 43 ? -64.831 -25.959 -8.110 1.00 35.23 ? 250 THR E CB 1 ATOM 5073 O OG1 . THR E 2 43 ? -63.820 -25.295 -8.868 1.00 37.80 ? 250 THR E OG1 1 ATOM 5074 C CG2 . THR E 2 43 ? -64.399 -26.019 -6.648 1.00 33.62 ? 250 THR E CG2 1 ATOM 5075 N N . LEU E 2 44 ? -64.527 -27.518 -11.079 1.00 37.22 ? 251 LEU E N 1 ATOM 5076 C CA . LEU E 2 44 ? -64.770 -27.320 -12.523 1.00 36.28 ? 251 LEU E CA 1 ATOM 5077 C C . LEU E 2 44 ? -65.104 -28.598 -13.265 1.00 37.98 ? 251 LEU E C 1 ATOM 5078 O O . LEU E 2 44 ? -65.480 -28.557 -14.438 1.00 47.40 ? 251 LEU E O 1 ATOM 5079 C CB . LEU E 2 44 ? -63.568 -26.644 -13.187 1.00 30.98 ? 251 LEU E CB 1 ATOM 5080 C CG . LEU E 2 44 ? -63.151 -25.303 -12.577 1.00 35.12 ? 251 LEU E CG 1 ATOM 5081 C CD1 . LEU E 2 44 ? -61.894 -24.763 -13.238 1.00 39.87 ? 251 LEU E CD1 1 ATOM 5082 C CD2 . LEU E 2 44 ? -64.280 -24.290 -12.653 1.00 33.42 ? 251 LEU E CD2 1 ATOM 5083 N N . GLU E 2 45 ? -64.950 -29.734 -12.589 1.00 44.58 ? 252 GLU E N 1 ATOM 5084 C CA . GLU E 2 45 ? -65.318 -31.031 -13.159 1.00 49.26 ? 252 GLU E CA 1 ATOM 5085 C C . GLU E 2 45 ? -66.457 -31.677 -12.376 1.00 45.98 ? 252 GLU E C 1 ATOM 5086 O O . GLU E 2 45 ? -66.351 -31.909 -11.164 1.00 44.82 ? 252 GLU E O 1 ATOM 5087 C CB . GLU E 2 45 ? -64.103 -31.963 -13.263 1.00 51.52 ? 252 GLU E CB 1 ATOM 5088 C CG . GLU E 2 45 ? -63.350 -31.837 -14.586 1.00 59.78 ? 252 GLU E CG 1 ATOM 5089 C CD . GLU E 2 45 ? -62.088 -32.685 -14.644 1.00 57.17 ? 252 GLU E CD 1 ATOM 5090 O OE1 . GLU E 2 45 ? -62.025 -33.610 -15.474 1.00 56.06 ? 252 GLU E OE1 1 ATOM 5091 O OE2 . GLU E 2 45 ? -61.153 -32.434 -13.861 1.00 57.03 ? 252 GLU E OE2 1 ATOM 5092 N N . ALA E 2 46 ? -67.545 -31.951 -13.091 1.00 44.26 ? 253 ALA E N 1 ATOM 5093 C CA . ALA E 2 46 ? -68.764 -32.539 -12.522 1.00 53.32 ? 253 ALA E CA 1 ATOM 5094 C C . ALA E 2 46 ? -68.536 -33.916 -11.894 1.00 54.70 ? 253 ALA E C 1 ATOM 5095 O O . ALA E 2 46 ? -69.162 -34.256 -10.883 1.00 55.83 ? 253 ALA E O 1 ATOM 5096 C CB . ALA E 2 46 ? -69.851 -32.615 -13.584 1.00 49.44 ? 253 ALA E CB 1 ATOM 5097 N N . SER E 2 47 ? -67.625 -34.689 -12.485 1.00 54.18 ? 254 SER E N 1 ATOM 5098 C CA . SER E 2 47 ? -67.311 -36.046 -12.023 1.00 59.61 ? 254 SER E CA 1 ATOM 5099 C C . SER E 2 47 ? -66.464 -36.093 -10.745 1.00 60.64 ? 254 SER E C 1 ATOM 5100 O O . SER E 2 47 ? -66.264 -37.167 -10.169 1.00 65.75 ? 254 SER E O 1 ATOM 5101 C CB . SER E 2 47 ? -66.620 -36.836 -13.135 1.00 57.36 ? 254 SER E CB 1 ATOM 5102 O OG . SER E 2 47 ? -65.411 -36.208 -13.521 1.00 68.46 ? 254 SER E OG 1 ATOM 5103 N N . ARG E 2 48 ? -65.972 -34.935 -10.307 1.00 55.94 ? 255 ARG E N 1 ATOM 5104 C CA . ARG E 2 48 ? -65.171 -34.847 -9.085 1.00 52.98 ? 255 ARG E CA 1 ATOM 5105 C C . ARG E 2 48 ? -65.983 -34.291 -7.917 1.00 47.45 ? 255 ARG E C 1 ATOM 5106 O O . ARG E 2 48 ? -67.034 -33.681 -8.125 1.00 52.87 ? 255 ARG E O 1 ATOM 5107 C CB . ARG E 2 48 ? -63.918 -34.005 -9.327 1.00 49.22 ? 255 ARG E CB 1 ATOM 5108 C CG . ARG E 2 48 ? -62.839 -34.738 -10.100 1.00 51.59 ? 255 ARG E CG 1 ATOM 5109 C CD . ARG E 2 48 ? -61.858 -33.769 -10.727 1.00 67.24 ? 255 ARG E CD 1 ATOM 5110 N NE . ARG E 2 48 ? -61.256 -34.330 -11.935 1.00 69.74 ? 255 ARG E NE 1 ATOM 5111 C CZ . ARG E 2 48 ? -60.014 -34.799 -12.019 1.00 72.90 ? 255 ARG E CZ 1 ATOM 5112 N NH1 . ARG E 2 48 ? -59.209 -34.777 -10.963 1.00 75.34 ? 255 ARG E NH1 1 ATOM 5113 N NH2 . ARG E 2 48 ? -59.573 -35.288 -13.172 1.00 70.52 ? 255 ARG E NH2 1 ATOM 5114 N N . THR E 2 49 ? -65.492 -34.509 -6.696 1.00 50.43 ? 256 THR E N 1 ATOM 5115 C CA . THR E 2 49 ? -66.188 -34.094 -5.469 1.00 51.54 ? 256 THR E CA 1 ATOM 5116 C C . THR E 2 49 ? -65.401 -33.009 -4.725 1.00 53.07 ? 256 THR E C 1 ATOM 5117 O O . THR E 2 49 ? -64.453 -33.317 -3.996 1.00 57.94 ? 256 THR E O 1 ATOM 5118 C CB . THR E 2 49 ? -66.446 -35.294 -4.530 1.00 52.21 ? 256 THR E CB 1 ATOM 5119 O OG1 . THR E 2 49 ? -67.216 -36.285 -5.218 1.00 62.84 ? 256 THR E OG1 1 ATOM 5120 C CG2 . THR E 2 49 ? -67.203 -34.860 -3.285 1.00 58.43 ? 256 THR E CG2 1 ATOM 5121 N N . PRO E 2 50 ? -65.787 -31.731 -4.914 1.00 47.80 ? 257 PRO E N 1 ATOM 5122 C CA . PRO E 2 50 ? -65.089 -30.623 -4.273 1.00 41.47 ? 257 PRO E CA 1 ATOM 5123 C C . PRO E 2 50 ? -65.406 -30.555 -2.791 1.00 40.69 ? 257 PRO E C 1 ATOM 5124 O O . PRO E 2 50 ? -66.533 -30.839 -2.386 1.00 35.78 ? 257 PRO E O 1 ATOM 5125 C CB . PRO E 2 50 ? -65.654 -29.400 -4.985 1.00 43.93 ? 257 PRO E CB 1 ATOM 5126 C CG . PRO E 2 50 ? -67.010 -29.821 -5.427 1.00 51.47 ? 257 PRO E CG 1 ATOM 5127 C CD . PRO E 2 50 ? -66.846 -31.257 -5.821 1.00 52.59 ? 257 PRO E CD 1 ATOM 5128 N N . GLU E 2 51 ? -64.422 -30.175 -1.985 1.00 36.68 ? 258 GLU E N 1 ATOM 5129 C CA . GLU E 2 51 ? -64.616 -30.164 -0.543 1.00 34.90 ? 258 GLU E CA 1 ATOM 5130 C C . GLU E 2 51 ? -63.814 -29.094 0.180 1.00 42.12 ? 258 GLU E C 1 ATOM 5131 O O . GLU E 2 51 ? -62.770 -28.632 -0.294 1.00 42.00 ? 258 GLU E O 1 ATOM 5132 C CB . GLU E 2 51 ? -64.317 -31.549 0.051 1.00 43.21 ? 258 GLU E CB 1 ATOM 5133 C CG . GLU E 2 51 ? -62.872 -31.999 -0.102 1.00 47.64 ? 258 GLU E CG 1 ATOM 5134 C CD . GLU E 2 51 ? -62.664 -33.489 0.114 1.00 57.06 ? 258 GLU E CD 1 ATOM 5135 O OE1 . GLU E 2 51 ? -61.550 -33.862 0.539 1.00 57.76 ? 258 GLU E OE1 1 ATOM 5136 O OE2 . GLU E 2 51 ? -63.593 -34.288 -0.147 1.00 60.02 ? 258 GLU E OE2 1 ATOM 5137 N N . VAL E 2 52 ? -64.324 -28.709 1.341 1.00 34.40 ? 259 VAL E N 1 ATOM 5138 C CA . VAL E 2 52 ? -63.686 -27.723 2.178 1.00 34.25 ? 259 VAL E CA 1 ATOM 5139 C C . VAL E 2 52 ? -63.201 -28.452 3.430 1.00 35.53 ? 259 VAL E C 1 ATOM 5140 O O . VAL E 2 52 ? -63.925 -29.281 4.011 1.00 29.88 ? 259 VAL E O 1 ATOM 5141 C CB . VAL E 2 52 ? -64.664 -26.567 2.490 1.00 34.06 ? 259 VAL E CB 1 ATOM 5142 C CG1 . VAL E 2 52 ? -64.057 -25.569 3.458 1.00 40.71 ? 259 VAL E CG1 1 ATOM 5143 C CG2 . VAL E 2 52 ? -65.018 -25.853 1.201 1.00 32.10 ? 259 VAL E CG2 1 ATOM 5144 N N . THR E 2 53 ? -61.966 -28.154 3.824 1.00 33.42 ? 260 THR E N 1 ATOM 5145 C CA . THR E 2 53 ? -61.295 -28.911 4.859 1.00 33.54 ? 260 THR E CA 1 ATOM 5146 C C . THR E 2 53 ? -60.924 -28.039 6.059 1.00 31.90 ? 260 THR E C 1 ATOM 5147 O O . THR E 2 53 ? -60.259 -27.020 5.909 1.00 37.51 ? 260 THR E O 1 ATOM 5148 C CB . THR E 2 53 ? -60.036 -29.605 4.296 1.00 32.65 ? 260 THR E CB 1 ATOM 5149 O OG1 . THR E 2 53 ? -60.345 -30.265 3.051 1.00 27.50 ? 260 THR E OG1 1 ATOM 5150 C CG2 . THR E 2 53 ? -59.509 -30.616 5.295 1.00 29.81 ? 260 THR E CG2 1 ATOM 5151 N N . CYS E 2 54 ? -61.337 -28.455 7.252 1.00 32.51 ? 261 CYS E N 1 ATOM 5152 C CA . CYS E 2 54 ? -61.026 -27.695 8.465 1.00 34.48 ? 261 CYS E CA 1 ATOM 5153 C C . CYS E 2 54 ? -59.995 -28.432 9.310 1.00 34.46 ? 261 CYS E C 1 ATOM 5154 O O . CYS E 2 54 ? -60.303 -29.455 9.916 1.00 30.20 ? 261 CYS E O 1 ATOM 5155 C CB . CYS E 2 54 ? -62.296 -27.427 9.268 1.00 37.56 ? 261 CYS E CB 1 ATOM 5156 S SG . CYS E 2 54 ? -62.182 -26.081 10.469 1.00 48.26 ? 261 CYS E SG 1 ATOM 5157 N N . VAL E 2 55 ? -58.772 -27.904 9.332 1.00 33.39 ? 262 VAL E N 1 ATOM 5158 C CA . VAL E 2 55 ? -57.647 -28.529 10.018 1.00 31.03 ? 262 VAL E CA 1 ATOM 5159 C C . VAL E 2 55 ? -57.340 -27.849 11.355 1.00 38.05 ? 262 VAL E C 1 ATOM 5160 O O . VAL E 2 55 ? -57.086 -26.643 11.418 1.00 46.52 ? 262 VAL E O 1 ATOM 5161 C CB . VAL E 2 55 ? -56.386 -28.509 9.142 1.00 36.89 ? 262 VAL E CB 1 ATOM 5162 C CG1 . VAL E 2 55 ? -55.243 -29.255 9.825 1.00 34.42 ? 262 VAL E CG1 1 ATOM 5163 C CG2 . VAL E 2 55 ? -56.683 -29.098 7.761 1.00 32.36 ? 262 VAL E CG2 1 ATOM 5164 N N . VAL E 2 56 ? -57.370 -28.637 12.421 1.00 38.57 ? 263 VAL E N 1 ATOM 5165 C CA . VAL E 2 56 ? -57.018 -28.161 13.747 1.00 35.39 ? 263 VAL E CA 1 ATOM 5166 C C . VAL E 2 56 ? -55.696 -28.801 14.158 1.00 46.77 ? 263 VAL E C 1 ATOM 5167 O O . VAL E 2 56 ? -55.574 -30.031 14.186 1.00 48.15 ? 263 VAL E O 1 ATOM 5168 C CB . VAL E 2 56 ? -58.105 -28.509 14.778 1.00 36.09 ? 263 VAL E CB 1 ATOM 5169 C CG1 . VAL E 2 56 ? -57.886 -27.737 16.067 1.00 36.90 ? 263 VAL E CG1 1 ATOM 5170 C CG2 . VAL E 2 56 ? -59.496 -28.230 14.226 1.00 27.87 ? 263 VAL E CG2 1 ATOM 5171 N N . VAL E 2 57 ? -54.704 -27.967 14.463 1.00 49.39 ? 264 VAL E N 1 ATOM 5172 C CA . VAL E 2 57 ? -53.404 -28.463 14.910 1.00 46.10 ? 264 VAL E CA 1 ATOM 5173 C C . VAL E 2 57 ? -53.177 -28.156 16.379 1.00 49.03 ? 264 VAL E C 1 ATOM 5174 O O . VAL E 2 57 ? -53.942 -27.406 16.981 1.00 52.07 ? 264 VAL E O 1 ATOM 5175 C CB . VAL E 2 57 ? -52.248 -27.918 14.050 1.00 40.32 ? 264 VAL E CB 1 ATOM 5176 C CG1 . VAL E 2 57 ? -52.340 -28.489 12.643 1.00 41.53 ? 264 VAL E CG1 1 ATOM 5177 C CG2 . VAL E 2 57 ? -52.261 -26.398 14.015 1.00 39.00 ? 264 VAL E CG2 1 ATOM 5178 N N . ASP E 2 58 ? -52.134 -28.753 16.948 1.00 44.48 ? 265 ASP E N 1 ATOM 5179 C CA . ASP E 2 58 ? -51.774 -28.577 18.360 1.00 52.69 ? 265 ASP E CA 1 ATOM 5180 C C . ASP E 2 58 ? -52.877 -28.948 19.351 1.00 57.35 ? 265 ASP E C 1 ATOM 5181 O O . ASP E 2 58 ? -52.938 -28.397 20.450 1.00 65.69 ? 265 ASP E O 1 ATOM 5182 C CB . ASP E 2 58 ? -51.252 -27.156 18.626 1.00 59.17 ? 265 ASP E CB 1 ATOM 5183 C CG . ASP E 2 58 ? -49.955 -26.866 17.898 1.00 60.63 ? 265 ASP E CG 1 ATOM 5184 O OD1 . ASP E 2 58 ? -49.327 -27.816 17.386 1.00 63.12 ? 265 ASP E OD1 1 ATOM 5185 O OD2 . ASP E 2 58 ? -49.559 -25.685 17.838 1.00 67.43 ? 265 ASP E OD2 1 ATOM 5186 N N . VAL E 2 59 ? -53.736 -29.888 18.953 1.00 60.05 ? 266 VAL E N 1 ATOM 5187 C CA . VAL E 2 59 ? -54.724 -30.489 19.856 1.00 61.76 ? 266 VAL E CA 1 ATOM 5188 C C . VAL E 2 59 ? -53.987 -31.367 20.869 1.00 61.24 ? 266 VAL E C 1 ATOM 5189 O O . VAL E 2 59 ? -53.135 -32.173 20.491 1.00 65.95 ? 266 VAL E O 1 ATOM 5190 C CB . VAL E 2 59 ? -55.787 -31.313 19.087 1.00 54.06 ? 266 VAL E CB 1 ATOM 5191 C CG1 . VAL E 2 59 ? -56.754 -31.993 20.046 1.00 49.68 ? 266 VAL E CG1 1 ATOM 5192 C CG2 . VAL E 2 59 ? -56.555 -30.423 18.122 1.00 47.71 ? 266 VAL E CG2 1 ATOM 5193 N N . SER E 2 60 ? -54.308 -31.195 22.150 1.00 58.39 ? 267 SER E N 1 ATOM 5194 C CA . SER E 2 60 ? -53.560 -31.848 23.223 1.00 64.92 ? 267 SER E CA 1 ATOM 5195 C C . SER E 2 60 ? -54.069 -33.255 23.542 1.00 71.63 ? 267 SER E C 1 ATOM 5196 O O . SER E 2 60 ? -55.196 -33.618 23.184 1.00 63.97 ? 267 SER E O 1 ATOM 5197 C CB . SER E 2 60 ? -53.566 -30.981 24.488 1.00 65.55 ? 267 SER E CB 1 ATOM 5198 O OG . SER E 2 60 ? -54.742 -31.183 25.253 1.00 58.00 ? 267 SER E OG 1 ATOM 5199 N N . HIS E 2 61 ? -53.220 -34.038 24.211 1.00 75.70 ? 268 HIS E N 1 ATOM 5200 C CA . HIS E 2 61 ? -53.609 -35.338 24.760 1.00 68.74 ? 268 HIS E CA 1 ATOM 5201 C C . HIS E 2 61 ? -54.567 -35.177 25.908 1.00 74.63 ? 268 HIS E C 1 ATOM 5202 O O . HIS E 2 61 ? -55.450 -36.013 26.097 1.00 79.72 ? 268 HIS E O 1 ATOM 5203 C CB . HIS E 2 61 ? -52.383 -36.118 25.212 1.00 66.71 ? 268 HIS E CB 1 ATOM 5204 C CG . HIS E 2 61 ? -51.647 -36.805 24.087 1.00 73.82 ? 268 HIS E CG 1 ATOM 5205 N ND1 . HIS E 2 61 ? -50.885 -36.134 23.204 1.00 74.82 ? 268 HIS E ND1 1 ATOM 5206 C CD2 . HIS E 2 61 ? -51.575 -38.149 23.727 1.00 76.16 ? 268 HIS E CD2 1 ATOM 5207 C CE1 . HIS E 2 61 ? -50.354 -37.001 22.322 1.00 67.90 ? 268 HIS E CE1 1 ATOM 5208 N NE2 . HIS E 2 61 ? -50.776 -38.233 22.644 1.00 70.18 ? 268 HIS E NE2 1 ATOM 5209 N N . GLU E 2 62 ? -54.398 -34.092 26.672 1.00 83.70 ? 269 GLU E N 1 ATOM 5210 C CA . GLU E 2 62 ? -55.241 -33.767 27.832 1.00 75.39 ? 269 GLU E CA 1 ATOM 5211 C C . GLU E 2 62 ? -56.736 -33.780 27.504 1.00 74.11 ? 269 GLU E C 1 ATOM 5212 O O . GLU E 2 62 ? -57.490 -34.556 28.093 1.00 59.96 ? 269 GLU E O 1 ATOM 5213 C CB . GLU E 2 62 ? -54.836 -32.416 28.431 1.00 68.15 ? 269 GLU E CB 1 ATOM 5214 N N . ASP E 2 63 ? -57.154 -32.930 26.564 1.00 79.77 ? 270 ASP E N 1 ATOM 5215 C CA . ASP E 2 63 ? -58.537 -32.918 26.071 1.00 72.80 ? 270 ASP E CA 1 ATOM 5216 C C . ASP E 2 63 ? -58.573 -32.969 24.529 1.00 66.26 ? 270 ASP E C 1 ATOM 5217 O O . ASP E 2 63 ? -58.461 -31.936 23.866 1.00 66.88 ? 270 ASP E O 1 ATOM 5218 C CB . ASP E 2 63 ? -59.298 -31.703 26.619 1.00 64.24 ? 270 ASP E CB 1 ATOM 5219 N N . PRO E 2 64 ? -58.721 -34.180 23.957 1.00 61.54 ? 271 PRO E N 1 ATOM 5220 C CA . PRO E 2 64 ? -58.613 -34.384 22.509 1.00 59.76 ? 271 PRO E CA 1 ATOM 5221 C C . PRO E 2 64 ? -59.914 -34.219 21.718 1.00 56.12 ? 271 PRO E C 1 ATOM 5222 O O . PRO E 2 64 ? -59.865 -34.088 20.493 1.00 46.14 ? 271 PRO E O 1 ATOM 5223 C CB . PRO E 2 64 ? -58.103 -35.825 22.396 1.00 58.51 ? 271 PRO E CB 1 ATOM 5224 C CG . PRO E 2 64 ? -58.536 -36.496 23.659 1.00 60.47 ? 271 PRO E CG 1 ATOM 5225 C CD . PRO E 2 64 ? -58.937 -35.453 24.668 1.00 65.91 ? 271 PRO E CD 1 ATOM 5226 N N . GLU E 2 65 ? -61.057 -34.239 22.404 1.00 57.77 ? 272 GLU E N 1 ATOM 5227 C CA . GLU E 2 65 ? -62.350 -34.067 21.749 1.00 50.51 ? 272 GLU E CA 1 ATOM 5228 C C . GLU E 2 65 ? -62.436 -32.677 21.132 1.00 54.92 ? 272 GLU E C 1 ATOM 5229 O O . GLU E 2 65 ? -62.061 -31.683 21.757 1.00 56.03 ? 272 GLU E O 1 ATOM 5230 C CB . GLU E 2 65 ? -63.505 -34.292 22.728 1.00 52.59 ? 272 GLU E CB 1 ATOM 5231 N N . VAL E 2 66 ? -62.900 -32.628 19.887 1.00 55.84 ? 273 VAL E N 1 ATOM 5232 C CA . VAL E 2 66 ? -63.080 -31.379 19.160 1.00 51.50 ? 273 VAL E CA 1 ATOM 5233 C C . VAL E 2 66 ? -64.471 -31.366 18.525 1.00 46.38 ? 273 VAL E C 1 ATOM 5234 O O . VAL E 2 66 ? -64.821 -32.267 17.765 1.00 48.42 ? 273 VAL E O 1 ATOM 5235 C CB . VAL E 2 66 ? -61.981 -31.186 18.086 1.00 50.98 ? 273 VAL E CB 1 ATOM 5236 C CG1 . VAL E 2 66 ? -62.307 -30.022 17.157 1.00 51.90 ? 273 VAL E CG1 1 ATOM 5237 C CG2 . VAL E 2 66 ? -60.621 -30.980 18.743 1.00 51.73 ? 273 VAL E CG2 1 ATOM 5238 N N . LYS E 2 67 ? -65.264 -30.355 18.863 1.00 43.44 ? 274 LYS E N 1 ATOM 5239 C CA . LYS E 2 67 ? -66.570 -30.159 18.242 1.00 46.55 ? 274 LYS E CA 1 ATOM 5240 C C . LYS E 2 67 ? -66.449 -29.255 17.019 1.00 46.58 ? 274 LYS E C 1 ATOM 5241 O O . LYS E 2 67 ? -65.800 -28.202 17.065 1.00 45.67 ? 274 LYS E O 1 ATOM 5242 C CB . LYS E 2 67 ? -67.568 -29.570 19.245 1.00 40.78 ? 274 LYS E CB 1 ATOM 5243 N N . PHE E 2 68 ? -67.064 -29.685 15.923 1.00 51.31 ? 275 PHE E N 1 ATOM 5244 C CA . PHE E 2 68 ? -67.128 -28.891 14.699 1.00 46.74 ? 275 PHE E CA 1 ATOM 5245 C C . PHE E 2 68 ? -68.556 -28.430 14.443 1.00 49.99 ? 275 PHE E C 1 ATOM 5246 O O . PHE E 2 68 ? -69.485 -29.239 14.450 1.00 55.56 ? 275 PHE E O 1 ATOM 5247 C CB . PHE E 2 68 ? -66.659 -29.713 13.496 1.00 43.31 ? 275 PHE E CB 1 ATOM 5248 C CG . PHE E 2 68 ? -65.191 -30.011 13.490 1.00 46.30 ? 275 PHE E CG 1 ATOM 5249 C CD1 . PHE E 2 68 ? -64.713 -31.213 13.998 1.00 43.03 ? 275 PHE E CD1 1 ATOM 5250 C CD2 . PHE E 2 68 ? -64.280 -29.087 12.971 1.00 44.09 ? 275 PHE E CD2 1 ATOM 5251 C CE1 . PHE E 2 68 ? -63.357 -31.492 13.991 1.00 40.79 ? 275 PHE E CE1 1 ATOM 5252 C CE2 . PHE E 2 68 ? -62.921 -29.355 12.965 1.00 36.99 ? 275 PHE E CE2 1 ATOM 5253 C CZ . PHE E 2 68 ? -62.459 -30.566 13.469 1.00 40.63 ? 275 PHE E CZ 1 ATOM 5254 N N . ASN E 2 69 ? -68.728 -27.126 14.233 1.00 47.56 ? 276 ASN E N 1 ATOM 5255 C CA . ASN E 2 69 ? -69.966 -26.593 13.681 1.00 41.72 ? 276 ASN E CA 1 ATOM 5256 C C . ASN E 2 69 ? -69.655 -25.942 12.340 1.00 43.26 ? 276 ASN E C 1 ATOM 5257 O O . ASN E 2 69 ? -68.767 -25.094 12.247 1.00 52.58 ? 276 ASN E O 1 ATOM 5258 C CB . ASN E 2 69 ? -70.606 -25.575 14.617 1.00 47.42 ? 276 ASN E CB 1 ATOM 5259 C CG . ASN E 2 69 ? -70.932 -26.148 15.980 1.00 49.21 ? 276 ASN E CG 1 ATOM 5260 O OD1 . ASN E 2 69 ? -70.049 -26.331 16.819 1.00 44.68 ? 276 ASN E OD1 1 ATOM 5261 N ND2 . ASN E 2 69 ? -72.213 -26.411 16.215 1.00 52.66 ? 276 ASN E ND2 1 ATOM 5262 N N . TRP E 2 70 ? -70.374 -26.361 11.307 1.00 40.46 ? 277 TRP E N 1 ATOM 5263 C CA . TRP E 2 70 ? -70.219 -25.808 9.962 1.00 41.35 ? 277 TRP E CA 1 ATOM 5264 C C . TRP E 2 70 ? -71.411 -24.990 9.559 1.00 49.57 ? 277 TRP E C 1 ATOM 5265 O O . TRP E 2 70 ? -72.560 -25.316 9.888 1.00 48.45 ? 277 TRP E O 1 ATOM 5266 C CB . TRP E 2 70 ? -70.027 -26.918 8.939 1.00 32.58 ? 277 TRP E CB 1 ATOM 5267 C CG . TRP E 2 70 ? -68.661 -27.558 8.953 1.00 40.75 ? 277 TRP E CG 1 ATOM 5268 C CD1 . TRP E 2 70 ? -68.210 -28.581 9.782 1.00 39.27 ? 277 TRP E CD1 1 ATOM 5269 C CD2 . TRP E 2 70 ? -67.525 -27.264 8.064 1.00 42.11 ? 277 TRP E CD2 1 ATOM 5270 N NE1 . TRP E 2 70 ? -66.914 -28.918 9.487 1.00 37.66 ? 277 TRP E NE1 1 ATOM 5271 C CE2 . TRP E 2 70 ? -66.443 -28.170 8.469 1.00 41.91 ? 277 TRP E CE2 1 ATOM 5272 C CE3 . TRP E 2 70 ? -67.301 -26.370 7.022 1.00 37.80 ? 277 TRP E CE3 1 ATOM 5273 C CZ2 . TRP E 2 70 ? -65.208 -28.168 7.838 1.00 43.79 ? 277 TRP E CZ2 1 ATOM 5274 C CZ3 . TRP E 2 70 ? -66.052 -26.378 6.391 1.00 37.40 ? 277 TRP E CZ3 1 ATOM 5275 C CH2 . TRP E 2 70 ? -65.032 -27.257 6.789 1.00 42.89 ? 277 TRP E CH2 1 ATOM 5276 N N . TYR E 2 71 ? -71.152 -23.923 8.814 1.00 48.03 ? 278 TYR E N 1 ATOM 5277 C CA . TYR E 2 71 ? -72.214 -23.057 8.360 1.00 44.00 ? 278 TYR E CA 1 ATOM 5278 C C . TYR E 2 71 ? -72.004 -22.666 6.909 1.00 45.33 ? 278 TYR E C 1 ATOM 5279 O O . TYR E 2 71 ? -70.894 -22.311 6.511 1.00 55.10 ? 278 TYR E O 1 ATOM 5280 C CB . TYR E 2 71 ? -72.289 -21.816 9.239 1.00 41.07 ? 278 TYR E CB 1 ATOM 5281 C CG . TYR E 2 71 ? -72.409 -22.086 10.729 1.00 40.46 ? 278 TYR E CG 1 ATOM 5282 C CD1 . TYR E 2 71 ? -71.272 -22.157 11.544 1.00 44.26 ? 278 TYR E CD1 1 ATOM 5283 C CD2 . TYR E 2 71 ? -73.655 -22.238 11.332 1.00 38.58 ? 278 TYR E CD2 1 ATOM 5284 C CE1 . TYR E 2 71 ? -71.379 -22.377 12.911 1.00 42.59 ? 278 TYR E CE1 1 ATOM 5285 C CE2 . TYR E 2 71 ? -73.770 -22.467 12.700 1.00 40.73 ? 278 TYR E CE2 1 ATOM 5286 C CZ . TYR E 2 71 ? -72.636 -22.533 13.483 1.00 45.71 ? 278 TYR E CZ 1 ATOM 5287 O OH . TYR E 2 71 ? -72.756 -22.761 14.841 1.00 50.38 ? 278 TYR E OH 1 ATOM 5288 N N . VAL E 2 72 ? -73.070 -22.758 6.120 1.00 37.39 ? 279 VAL E N 1 ATOM 5289 C CA . VAL E 2 72 ? -73.084 -22.217 4.774 1.00 34.87 ? 279 VAL E CA 1 ATOM 5290 C C . VAL E 2 72 ? -73.957 -20.960 4.796 1.00 41.50 ? 279 VAL E C 1 ATOM 5291 O O . VAL E 2 72 ? -75.173 -21.039 5.019 1.00 44.58 ? 279 VAL E O 1 ATOM 5292 C CB . VAL E 2 72 ? -73.626 -23.234 3.754 1.00 39.46 ? 279 VAL E CB 1 ATOM 5293 C CG1 . VAL E 2 72 ? -73.333 -22.767 2.338 1.00 40.87 ? 279 VAL E CG1 1 ATOM 5294 C CG2 . VAL E 2 72 ? -73.019 -24.609 3.992 1.00 41.32 ? 279 VAL E CG2 1 ATOM 5295 N N . ASP E 2 73 ? -73.318 -19.804 4.581 1.00 41.18 ? 280 ASP E N 1 ATOM 5296 C CA . ASP E 2 73 ? -73.940 -18.478 4.756 1.00 43.62 ? 280 ASP E CA 1 ATOM 5297 C C . ASP E 2 73 ? -74.651 -18.310 6.109 1.00 45.38 ? 280 ASP E C 1 ATOM 5298 O O . ASP E 2 73 ? -75.740 -17.752 6.181 1.00 51.78 ? 280 ASP E O 1 ATOM 5299 C CB . ASP E 2 73 ? -74.904 -18.153 3.611 1.00 42.92 ? 280 ASP E CB 1 ATOM 5300 C CG . ASP E 2 73 ? -74.231 -18.155 2.243 1.00 41.97 ? 280 ASP E CG 1 ATOM 5301 O OD1 . ASP E 2 73 ? -73.009 -17.916 2.142 1.00 35.96 ? 280 ASP E OD1 1 ATOM 5302 O OD2 . ASP E 2 73 ? -74.950 -18.381 1.255 1.00 47.57 ? 280 ASP E OD2 1 ATOM 5303 N N . GLY E 2 74 ? -74.024 -18.797 7.175 1.00 47.82 ? 281 GLY E N 1 ATOM 5304 C CA . GLY E 2 74 ? -74.567 -18.661 8.527 1.00 42.72 ? 281 GLY E CA 1 ATOM 5305 C C . GLY E 2 74 ? -75.604 -19.715 8.873 1.00 43.54 ? 281 GLY E C 1 ATOM 5306 O O . GLY E 2 74 ? -76.082 -19.761 10.008 1.00 40.68 ? 281 GLY E O 1 ATOM 5307 N N . VAL E 2 75 ? -75.951 -20.558 7.899 1.00 46.11 ? 282 VAL E N 1 ATOM 5308 C CA . VAL E 2 75 ? -76.943 -21.634 8.085 1.00 55.51 ? 282 VAL E CA 1 ATOM 5309 C C . VAL E 2 75 ? -76.229 -22.956 8.358 1.00 52.54 ? 282 VAL E C 1 ATOM 5310 O O . VAL E 2 75 ? -75.468 -23.440 7.513 1.00 52.68 ? 282 VAL E O 1 ATOM 5311 C CB . VAL E 2 75 ? -77.862 -21.792 6.842 1.00 67.95 ? 282 VAL E CB 1 ATOM 5312 C CG1 . VAL E 2 75 ? -78.812 -22.974 7.001 1.00 66.14 ? 282 VAL E CG1 1 ATOM 5313 C CG2 . VAL E 2 75 ? -78.644 -20.512 6.574 1.00 68.35 ? 282 VAL E CG2 1 ATOM 5314 N N . GLU E 2 76 ? -76.484 -23.536 9.530 1.00 50.90 ? 283 GLU E N 1 ATOM 5315 C CA . GLU E 2 76 ? -75.779 -24.744 9.982 1.00 52.97 ? 283 GLU E CA 1 ATOM 5316 C C . GLU E 2 76 ? -76.052 -25.975 9.117 1.00 54.99 ? 283 GLU E C 1 ATOM 5317 O O . GLU E 2 76 ? -77.201 -26.261 8.783 1.00 66.84 ? 283 GLU E O 1 ATOM 5318 C CB . GLU E 2 76 ? -76.085 -25.034 11.460 1.00 46.17 ? 283 GLU E CB 1 ATOM 5319 C CG . GLU E 2 76 ? -75.322 -26.209 12.055 1.00 51.75 ? 283 GLU E CG 1 ATOM 5320 C CD . GLU E 2 76 ? -75.230 -26.162 13.573 1.00 60.90 ? 283 GLU E CD 1 ATOM 5321 O OE1 . GLU E 2 76 ? -76.192 -25.710 14.231 1.00 65.33 ? 283 GLU E OE1 1 ATOM 5322 O OE2 . GLU E 2 76 ? -74.188 -26.587 14.116 1.00 63.58 ? 283 GLU E OE2 1 ATOM 5323 N N . VAL E 2 77 ? -74.982 -26.681 8.746 1.00 51.99 ? 284 VAL E N 1 ATOM 5324 C CA . VAL E 2 77 ? -75.091 -27.976 8.058 1.00 45.20 ? 284 VAL E CA 1 ATOM 5325 C C . VAL E 2 77 ? -74.456 -29.084 8.894 1.00 47.81 ? 284 VAL E C 1 ATOM 5326 O O . VAL E 2 77 ? -73.643 -28.814 9.784 1.00 50.29 ? 284 VAL E O 1 ATOM 5327 C CB . VAL E 2 77 ? -74.495 -27.963 6.631 1.00 45.86 ? 284 VAL E CB 1 ATOM 5328 C CG1 . VAL E 2 77 ? -75.391 -27.177 5.681 1.00 44.14 ? 284 VAL E CG1 1 ATOM 5329 C CG2 . VAL E 2 77 ? -73.071 -27.416 6.627 1.00 48.46 ? 284 VAL E CG2 1 ATOM 5330 N N . HIS E 2 78 ? -74.824 -30.328 8.602 1.00 49.88 ? 285 HIS E N 1 ATOM 5331 C CA . HIS E 2 78 ? -74.474 -31.448 9.477 1.00 53.42 ? 285 HIS E CA 1 ATOM 5332 C C . HIS E 2 78 ? -73.839 -32.614 8.765 1.00 51.33 ? 285 HIS E C 1 ATOM 5333 O O . HIS E 2 78 ? -73.570 -33.646 9.375 1.00 51.96 ? 285 HIS E O 1 ATOM 5334 C CB . HIS E 2 78 ? -75.706 -31.887 10.274 1.00 57.28 ? 285 HIS E CB 1 ATOM 5335 C CG . HIS E 2 78 ? -76.310 -30.782 11.120 1.00 54.61 ? 285 HIS E CG 1 ATOM 5336 N ND1 . HIS E 2 78 ? -77.295 -29.979 10.669 1.00 53.35 ? 285 HIS E ND1 1 ATOM 5337 C CD2 . HIS E 2 78 ? -76.018 -30.357 12.417 1.00 54.87 ? 285 HIS E CD2 1 ATOM 5338 C CE1 . HIS E 2 78 ? -77.627 -29.093 11.629 1.00 49.38 ? 285 HIS E CE1 1 ATOM 5339 N NE2 . HIS E 2 78 ? -76.844 -29.326 12.698 1.00 54.58 ? 285 HIS E NE2 1 ATOM 5340 N N . ASN E 2 79 ? -73.569 -32.447 7.473 1.00 47.29 ? 286 ASN E N 1 ATOM 5341 C CA . ASN E 2 79 ? -73.012 -33.513 6.647 1.00 47.25 ? 286 ASN E CA 1 ATOM 5342 C C . ASN E 2 79 ? -71.471 -33.576 6.622 1.00 48.25 ? 286 ASN E C 1 ATOM 5343 O O . ASN E 2 79 ? -70.892 -34.248 5.760 1.00 44.52 ? 286 ASN E O 1 ATOM 5344 C CB . ASN E 2 79 ? -73.559 -33.410 5.221 1.00 43.14 ? 286 ASN E CB 1 ATOM 5345 C CG . ASN E 2 79 ? -73.253 -32.071 4.574 1.00 53.79 ? 286 ASN E CG 1 ATOM 5346 O OD1 . ASN E 2 79 ? -73.246 -31.034 5.240 1.00 50.10 ? 286 ASN E OD1 1 ATOM 5347 N ND2 . ASN E 2 79 ? -73.000 -32.085 3.267 1.00 52.50 ? 286 ASN E ND2 1 ATOM 5348 N N . ALA E 2 80 ? -70.809 -32.896 7.560 1.00 35.57 ? 287 ALA E N 1 ATOM 5349 C CA . ALA E 2 80 ? -69.345 -32.960 7.634 1.00 42.09 ? 287 ALA E CA 1 ATOM 5350 C C . ALA E 2 80 ? -68.895 -34.294 8.225 1.00 50.87 ? 287 ALA E C 1 ATOM 5351 O O . ALA E 2 80 ? -69.592 -34.881 9.055 1.00 48.11 ? 287 ALA E O 1 ATOM 5352 C CB . ALA E 2 80 ? -68.781 -31.803 8.439 1.00 35.72 ? 287 ALA E CB 1 ATOM 5353 N N . LYS E 2 81 ? -67.737 -34.773 7.778 1.00 51.03 ? 288 LYS E N 1 ATOM 5354 C CA . LYS E 2 81 ? -67.169 -36.018 8.281 1.00 44.83 ? 288 LYS E CA 1 ATOM 5355 C C . LYS E 2 81 ? -65.753 -35.800 8.774 1.00 42.36 ? 288 LYS E C 1 ATOM 5356 O O . LYS E 2 81 ? -64.931 -35.180 8.085 1.00 41.01 ? 288 LYS E O 1 ATOM 5357 C CB . LYS E 2 81 ? -67.192 -37.109 7.209 1.00 49.04 ? 288 LYS E CB 1 ATOM 5358 C CG . LYS E 2 81 ? -68.546 -37.787 7.031 1.00 52.45 ? 288 LYS E CG 1 ATOM 5359 C CD . LYS E 2 81 ? -69.318 -37.221 5.843 1.00 61.61 ? 288 LYS E CD 1 ATOM 5360 C CE . LYS E 2 81 ? -68.772 -37.716 4.509 1.00 55.58 ? 288 LYS E CE 1 ATOM 5361 N NZ . LYS E 2 81 ? -69.128 -39.139 4.254 1.00 60.44 ? 288 LYS E NZ 1 ATOM 5362 N N . THR E 2 82 ? -65.479 -36.305 9.975 1.00 36.46 ? 289 THR E N 1 ATOM 5363 C CA . THR E 2 82 ? -64.168 -36.182 10.585 1.00 34.17 ? 289 THR E CA 1 ATOM 5364 C C . THR E 2 82 ? -63.237 -37.287 10.090 1.00 36.64 ? 289 THR E C 1 ATOM 5365 O O . THR E 2 82 ? -63.571 -38.473 10.160 1.00 38.00 ? 289 THR E O 1 ATOM 5366 C CB . THR E 2 82 ? -64.250 -36.281 12.119 1.00 37.80 ? 289 THR E CB 1 ATOM 5367 O OG1 . THR E 2 82 ? -65.487 -35.724 12.582 1.00 36.53 ? 289 THR E OG1 1 ATOM 5368 C CG2 . THR E 2 82 ? -63.072 -35.573 12.765 1.00 33.31 ? 289 THR E CG2 1 ATOM 5369 N N . LYS E 2 83 ? -62.066 -36.882 9.601 1.00 40.87 ? 290 LYS E N 1 ATOM 5370 C CA . LYS E 2 83 ? -61.013 -37.803 9.173 1.00 34.97 ? 290 LYS E CA 1 ATOM 5371 C C . LYS E 2 83 ? -60.423 -38.498 10.399 1.00 39.07 ? 290 LYS E C 1 ATOM 5372 O O . LYS E 2 83 ? -60.671 -38.070 11.536 1.00 38.21 ? 290 LYS E O 1 ATOM 5373 C CB . LYS E 2 83 ? -59.914 -37.040 8.421 1.00 36.30 ? 290 LYS E CB 1 ATOM 5374 C CG . LYS E 2 83 ? -60.350 -36.408 7.105 1.00 40.10 ? 290 LYS E CG 1 ATOM 5375 C CD . LYS E 2 83 ? -60.018 -37.290 5.909 1.00 50.53 ? 290 LYS E CD 1 ATOM 5376 C CE . LYS E 2 83 ? -60.757 -36.822 4.664 1.00 53.06 ? 290 LYS E CE 1 ATOM 5377 N NZ . LYS E 2 83 ? -60.215 -37.419 3.411 1.00 65.23 ? 290 LYS E NZ 1 ATOM 5378 N N . PRO E 2 84 ? -59.649 -39.580 10.184 1.00 39.66 ? 291 PRO E N 1 ATOM 5379 C CA . PRO E 2 84 ? -59.010 -40.246 11.328 1.00 34.16 ? 291 PRO E CA 1 ATOM 5380 C C . PRO E 2 84 ? -58.064 -39.312 12.074 1.00 35.76 ? 291 PRO E C 1 ATOM 5381 O O . PRO E 2 84 ? -57.316 -38.545 11.452 1.00 32.15 ? 291 PRO E O 1 ATOM 5382 C CB . PRO E 2 84 ? -58.217 -41.390 10.691 1.00 38.90 ? 291 PRO E CB 1 ATOM 5383 C CG . PRO E 2 84 ? -58.781 -41.565 9.316 1.00 42.73 ? 291 PRO E CG 1 ATOM 5384 C CD . PRO E 2 84 ? -59.354 -40.246 8.901 1.00 38.41 ? 291 PRO E CD 1 ATOM 5385 N N . ARG E 2 85 ? -58.115 -39.372 13.401 1.00 33.55 ? 292 ARG E N 1 ATOM 5386 C CA . ARG E 2 85 ? -57.221 -38.602 14.248 1.00 32.61 ? 292 ARG E CA 1 ATOM 5387 C C . ARG E 2 85 ? -55.776 -38.951 13.904 1.00 37.51 ? 292 ARG E C 1 ATOM 5388 O O . ARG E 2 85 ? -55.461 -40.099 13.580 1.00 38.39 ? 292 ARG E O 1 ATOM 5389 C CB . ARG E 2 85 ? -57.506 -38.907 15.716 1.00 33.57 ? 292 ARG E CB 1 ATOM 5390 C CG . ARG E 2 85 ? -56.938 -37.882 16.676 1.00 37.87 ? 292 ARG E CG 1 ATOM 5391 C CD . ARG E 2 85 ? -57.437 -38.121 18.091 1.00 43.81 ? 292 ARG E CD 1 ATOM 5392 N NE . ARG E 2 85 ? -56.955 -39.392 18.619 1.00 48.93 ? 292 ARG E NE 1 ATOM 5393 C CZ . ARG E 2 85 ? -57.186 -39.839 19.849 1.00 48.39 ? 292 ARG E CZ 1 ATOM 5394 N NH1 . ARG E 2 85 ? -57.897 -39.121 20.710 1.00 47.44 ? 292 ARG E NH1 1 ATOM 5395 N NH2 . ARG E 2 85 ? -56.694 -41.011 20.217 1.00 50.10 ? 292 ARG E NH2 1 ATOM 5396 N N . GLU E 2 86 ? -54.904 -37.953 13.951 1.00 38.66 ? 293 GLU E N 1 ATOM 5397 C CA . GLU E 2 86 ? -53.523 -38.141 13.531 1.00 44.24 ? 293 GLU E CA 1 ATOM 5398 C C . GLU E 2 86 ? -52.578 -37.522 14.557 1.00 47.35 ? 293 GLU E C 1 ATOM 5399 O O . GLU E 2 86 ? -52.579 -36.308 14.770 1.00 54.41 ? 293 GLU E O 1 ATOM 5400 C CB . GLU E 2 86 ? -53.320 -37.553 12.130 1.00 40.53 ? 293 GLU E CB 1 ATOM 5401 C CG . GLU E 2 86 ? -52.009 -37.906 11.452 1.00 46.87 ? 293 GLU E CG 1 ATOM 5402 C CD . GLU E 2 86 ? -51.807 -37.135 10.154 1.00 57.58 ? 293 GLU E CD 1 ATOM 5403 O OE1 . GLU E 2 86 ? -51.056 -36.134 10.160 1.00 58.85 ? 293 GLU E OE1 1 ATOM 5404 O OE2 . GLU E 2 86 ? -52.410 -37.516 9.129 1.00 59.10 ? 293 GLU E OE2 1 ATOM 5405 N N . GLU E 2 87 ? -51.804 -38.377 15.216 1.00 51.02 ? 294 GLU E N 1 ATOM 5406 C CA . GLU E 2 87 ? -50.760 -37.935 16.134 1.00 60.61 ? 294 GLU E CA 1 ATOM 5407 C C . GLU E 2 87 ? -49.599 -37.351 15.338 1.00 52.30 ? 294 GLU E C 1 ATOM 5408 O O . GLU E 2 87 ? -49.190 -37.916 14.324 1.00 42.31 ? 294 GLU E O 1 ATOM 5409 C CB . GLU E 2 87 ? -50.296 -39.104 17.014 1.00 69.42 ? 294 GLU E CB 1 ATOM 5410 C CG . GLU E 2 87 ? -49.037 -38.859 17.839 1.00 82.43 ? 294 GLU E CG 1 ATOM 5411 C CD . GLU E 2 87 ? -49.259 -37.964 19.047 1.00 94.70 ? 294 GLU E CD 1 ATOM 5412 O OE1 . GLU E 2 87 ? -48.308 -37.815 19.842 1.00 97.94 ? 294 GLU E OE1 1 ATOM 5413 O OE2 . GLU E 2 87 ? -50.368 -37.410 19.210 1.00 103.74 ? 294 GLU E OE2 1 ATOM 5414 N N . GLN E 2 88 ? -49.091 -36.208 15.789 1.00 55.14 ? 295 GLN E N 1 ATOM 5415 C CA . GLN E 2 88 ? -47.927 -35.578 15.162 1.00 54.96 ? 295 GLN E CA 1 ATOM 5416 C C . GLN E 2 88 ? -46.627 -35.961 15.868 1.00 54.13 ? 295 GLN E C 1 ATOM 5417 O O . GLN E 2 88 ? -46.640 -36.365 17.032 1.00 58.65 ? 295 GLN E O 1 ATOM 5418 C CB . GLN E 2 88 ? -48.092 -34.054 15.117 1.00 47.08 ? 295 GLN E CB 1 ATOM 5419 C CG . GLN E 2 88 ? -49.262 -33.586 14.267 1.00 51.36 ? 295 GLN E CG 1 ATOM 5420 C CD . GLN E 2 88 ? -49.205 -34.120 12.847 1.00 53.70 ? 295 GLN E CD 1 ATOM 5421 O OE1 . GLN E 2 88 ? -48.350 -33.725 12.055 1.00 56.05 ? 295 GLN E OE1 1 ATOM 5422 N NE2 . GLN E 2 88 ? -50.122 -35.023 12.519 1.00 59.55 ? 295 GLN E NE2 1 ATOM 5423 N N . TYR E 2 89 ? -45.508 -35.830 15.157 1.00 65.78 ? 296 TYR E N 1 ATOM 5424 C CA . TYR E 2 89 ? -44.187 -36.141 15.712 1.00 63.83 ? 296 TYR E CA 1 ATOM 5425 C C . TYR E 2 89 ? -43.887 -35.319 16.969 1.00 60.47 ? 296 TYR E C 1 ATOM 5426 O O . TYR E 2 89 ? -43.152 -35.771 17.853 1.00 66.14 ? 296 TYR E O 1 ATOM 5427 C CB . TYR E 2 89 ? -43.094 -35.935 14.659 1.00 55.85 ? 296 TYR E CB 1 ATOM 5428 N N . ASN E 2 90 ? -44.477 -34.127 17.047 1.00 59.46 ? 297 ASN E N 1 ATOM 5429 C CA . ASN E 2 90 ? -44.294 -33.229 18.190 1.00 63.72 ? 297 ASN E CA 1 ATOM 5430 C C . ASN E 2 90 ? -45.336 -33.393 19.310 1.00 65.63 ? 297 ASN E C 1 ATOM 5431 O O . ASN E 2 90 ? -45.662 -32.429 20.012 1.00 58.35 ? 297 ASN E O 1 ATOM 5432 C CB . ASN E 2 90 ? -44.238 -31.771 17.712 1.00 66.71 ? 297 ASN E CB 1 ATOM 5433 C CG . ASN E 2 90 ? -45.481 -31.357 16.944 1.00 70.70 ? 297 ASN E CG 1 ATOM 5434 O OD1 . ASN E 2 90 ? -46.526 -32.008 17.021 1.00 61.55 ? 297 ASN E OD1 1 ATOM 5435 N ND2 . ASN E 2 90 ? -45.373 -30.263 16.198 1.00 68.61 ? 297 ASN E ND2 1 ATOM 5436 N N . SER E 2 91 ? -45.863 -34.612 19.447 1.00 69.85 ? 298 SER E N 1 ATOM 5437 C CA . SER E 2 91 ? -46.705 -35.031 20.591 1.00 76.64 ? 298 SER E CA 1 ATOM 5438 C C . SER E 2 91 ? -48.103 -34.391 20.716 1.00 71.71 ? 298 SER E C 1 ATOM 5439 O O . SER E 2 91 ? -48.742 -34.490 21.766 1.00 68.11 ? 298 SER E O 1 ATOM 5440 C CB . SER E 2 91 ? -45.932 -34.916 21.919 1.00 73.42 ? 298 SER E CB 1 ATOM 5441 N N . THR E 2 92 ? -48.576 -33.747 19.650 1.00 73.43 ? 299 THR E N 1 ATOM 5442 C CA . THR E 2 92 ? -49.929 -33.175 19.631 1.00 59.62 ? 299 THR E CA 1 ATOM 5443 C C . THR E 2 92 ? -50.772 -33.849 18.557 1.00 58.67 ? 299 THR E C 1 ATOM 5444 O O . THR E 2 92 ? -50.244 -34.593 17.725 1.00 53.58 ? 299 THR E O 1 ATOM 5445 C CB . THR E 2 92 ? -49.920 -31.651 19.384 1.00 63.71 ? 299 THR E CB 1 ATOM 5446 O OG1 . THR E 2 92 ? -49.248 -31.360 18.150 1.00 57.87 ? 299 THR E OG1 1 ATOM 5447 C CG2 . THR E 2 92 ? -49.234 -30.913 20.531 1.00 68.57 ? 299 THR E CG2 1 ATOM 5448 N N . TYR E 2 93 ? -52.078 -33.586 18.580 1.00 51.64 ? 300 TYR E N 1 ATOM 5449 C CA . TYR E 2 93 ? -53.006 -34.168 17.613 1.00 53.94 ? 300 TYR E CA 1 ATOM 5450 C C . TYR E 2 93 ? -53.412 -33.214 16.490 1.00 53.28 ? 300 TYR E C 1 ATOM 5451 O O . TYR E 2 93 ? -53.548 -32.006 16.702 1.00 48.33 ? 300 TYR E O 1 ATOM 5452 C CB . TYR E 2 93 ? -54.255 -34.707 18.313 1.00 50.90 ? 300 TYR E CB 1 ATOM 5453 C CG . TYR E 2 93 ? -54.088 -36.088 18.907 1.00 57.55 ? 300 TYR E CG 1 ATOM 5454 C CD1 . TYR E 2 93 ? -54.371 -36.326 20.251 1.00 66.04 ? 300 TYR E CD1 1 ATOM 5455 C CD2 . TYR E 2 93 ? -53.652 -37.160 18.125 1.00 63.36 ? 300 TYR E CD2 1 ATOM 5456 C CE1 . TYR E 2 93 ? -54.221 -37.590 20.801 1.00 77.82 ? 300 TYR E CE1 1 ATOM 5457 C CE2 . TYR E 2 93 ? -53.500 -38.428 18.664 1.00 68.74 ? 300 TYR E CE2 1 ATOM 5458 C CZ . TYR E 2 93 ? -53.785 -38.637 20.002 1.00 76.03 ? 300 TYR E CZ 1 ATOM 5459 O OH . TYR E 2 93 ? -53.638 -39.892 20.545 1.00 79.84 ? 300 TYR E OH 1 ATOM 5460 N N . ARG E 2 94 ? -53.602 -33.789 15.304 1.00 45.39 ? 301 ARG E N 1 ATOM 5461 C CA . ARG E 2 94 ? -54.087 -33.085 14.122 1.00 45.12 ? 301 ARG E CA 1 ATOM 5462 C C . ARG E 2 94 ? -55.508 -33.582 13.836 1.00 46.71 ? 301 ARG E C 1 ATOM 5463 O O . ARG E 2 94 ? -55.706 -34.757 13.496 1.00 50.83 ? 301 ARG E O 1 ATOM 5464 C CB . ARG E 2 94 ? -53.181 -33.393 12.922 1.00 35.28 ? 301 ARG E CB 1 ATOM 5465 C CG . ARG E 2 94 ? -53.161 -32.335 11.832 1.00 38.32 ? 301 ARG E CG 1 ATOM 5466 C CD . ARG E 2 94 ? -52.992 -32.957 10.446 1.00 46.55 ? 301 ARG E CD 1 ATOM 5467 N NE . ARG E 2 94 ? -52.799 -31.947 9.403 1.00 43.36 ? 301 ARG E NE 1 ATOM 5468 C CZ . ARG E 2 94 ? -53.228 -32.055 8.142 1.00 53.74 ? 301 ARG E CZ 1 ATOM 5469 N NH1 . ARG E 2 94 ? -53.902 -33.130 7.742 1.00 51.66 ? 301 ARG E NH1 1 ATOM 5470 N NH2 . ARG E 2 94 ? -52.993 -31.072 7.275 1.00 44.76 ? 301 ARG E NH2 1 ATOM 5471 N N . VAL E 2 95 ? -56.491 -32.694 13.985 1.00 43.57 ? 302 VAL E N 1 ATOM 5472 C CA . VAL E 2 95 ? -57.904 -33.050 13.797 1.00 35.84 ? 302 VAL E CA 1 ATOM 5473 C C . VAL E 2 95 ? -58.486 -32.333 12.589 1.00 35.50 ? 302 VAL E C 1 ATOM 5474 O O . VAL E 2 95 ? -58.441 -31.105 12.498 1.00 43.88 ? 302 VAL E O 1 ATOM 5475 C CB . VAL E 2 95 ? -58.758 -32.721 15.038 1.00 36.91 ? 302 VAL E CB 1 ATOM 5476 C CG1 . VAL E 2 95 ? -60.171 -33.267 14.874 1.00 29.58 ? 302 VAL E CG1 1 ATOM 5477 C CG2 . VAL E 2 95 ? -58.118 -33.284 16.301 1.00 37.48 ? 302 VAL E CG2 1 ATOM 5478 N N . VAL E 2 96 ? -59.053 -33.110 11.678 1.00 32.91 ? 303 VAL E N 1 ATOM 5479 C CA . VAL E 2 96 ? -59.513 -32.593 10.401 1.00 33.59 ? 303 VAL E CA 1 ATOM 5480 C C . VAL E 2 96 ? -60.985 -32.953 10.158 1.00 32.59 ? 303 VAL E C 1 ATOM 5481 O O . VAL E 2 96 ? -61.364 -34.119 10.226 1.00 35.55 ? 303 VAL E O 1 ATOM 5482 C CB . VAL E 2 96 ? -58.662 -33.179 9.261 1.00 29.45 ? 303 VAL E CB 1 ATOM 5483 C CG1 . VAL E 2 96 ? -59.142 -32.683 7.907 1.00 29.87 ? 303 VAL E CG1 1 ATOM 5484 C CG2 . VAL E 2 96 ? -57.185 -32.886 9.474 1.00 33.34 ? 303 VAL E CG2 1 ATOM 5485 N N . SER E 2 97 ? -61.805 -31.945 9.872 1.00 32.06 ? 304 SER E N 1 ATOM 5486 C CA . SER E 2 97 ? -63.172 -32.161 9.418 1.00 30.89 ? 304 SER E CA 1 ATOM 5487 C C . SER E 2 97 ? -63.307 -31.688 7.974 1.00 30.32 ? 304 SER E C 1 ATOM 5488 O O . SER E 2 97 ? -62.837 -30.612 7.611 1.00 36.42 ? 304 SER E O 1 ATOM 5489 C CB . SER E 2 97 ? -64.174 -31.435 10.318 1.00 32.36 ? 304 SER E CB 1 ATOM 5490 O OG . SER E 2 97 ? -65.488 -31.474 9.767 1.00 35.91 ? 304 SER E OG 1 ATOM 5491 N N . VAL E 2 98 ? -63.950 -32.507 7.158 1.00 34.10 ? 305 VAL E N 1 ATOM 5492 C CA . VAL E 2 98 ? -64.122 -32.230 5.743 1.00 27.84 ? 305 VAL E CA 1 ATOM 5493 C C . VAL E 2 98 ? -65.604 -32.023 5.464 1.00 34.05 ? 305 VAL E C 1 ATOM 5494 O O . VAL E 2 98 ? -66.440 -32.835 5.876 1.00 34.90 ? 305 VAL E O 1 ATOM 5495 C CB . VAL E 2 98 ? -63.615 -33.406 4.896 1.00 35.97 ? 305 VAL E CB 1 ATOM 5496 C CG1 . VAL E 2 98 ? -63.850 -33.147 3.413 1.00 35.29 ? 305 VAL E CG1 1 ATOM 5497 C CG2 . VAL E 2 98 ? -62.135 -33.651 5.173 1.00 41.11 ? 305 VAL E CG2 1 ATOM 5498 N N . LEU E 2 99 ? -65.923 -30.918 4.793 1.00 31.94 ? 306 LEU E N 1 ATOM 5499 C CA . LEU E 2 99 ? -67.273 -30.654 4.330 1.00 29.83 ? 306 LEU E CA 1 ATOM 5500 C C . LEU E 2 99 ? -67.331 -30.698 2.802 1.00 30.63 ? 306 LEU E C 1 ATOM 5501 O O . LEU E 2 99 ? -66.648 -29.927 2.131 1.00 36.26 ? 306 LEU E O 1 ATOM 5502 C CB . LEU E 2 99 ? -67.752 -29.281 4.815 1.00 31.72 ? 306 LEU E CB 1 ATOM 5503 C CG . LEU E 2 99 ? -69.197 -28.907 4.440 1.00 33.39 ? 306 LEU E CG 1 ATOM 5504 C CD1 . LEU E 2 99 ? -70.161 -29.695 5.310 1.00 26.76 ? 306 LEU E CD1 1 ATOM 5505 C CD2 . LEU E 2 99 ? -69.443 -27.403 4.557 1.00 32.02 ? 306 LEU E CD2 1 ATOM 5506 N N . THR E 2 100 ? -68.157 -31.594 2.266 1.00 33.54 ? 307 THR E N 1 ATOM 5507 C CA . THR E 2 100 ? -68.419 -31.653 0.829 1.00 34.97 ? 307 THR E CA 1 ATOM 5508 C C . THR E 2 100 ? -69.305 -30.472 0.406 1.00 40.17 ? 307 THR E C 1 ATOM 5509 O O . THR E 2 100 ? -70.110 -29.977 1.198 1.00 43.13 ? 307 THR E O 1 ATOM 5510 C CB . THR E 2 100 ? -69.061 -33.002 0.439 1.00 37.95 ? 307 THR E CB 1 ATOM 5511 O OG1 . THR E 2 100 ? -68.139 -34.060 0.725 1.00 38.10 ? 307 THR E OG1 1 ATOM 5512 C CG2 . THR E 2 100 ? -69.401 -33.049 -1.046 1.00 43.32 ? 307 THR E CG2 1 ATOM 5513 N N . VAL E 2 101 ? -69.131 -30.008 -0.829 1.00 32.64 ? 308 VAL E N 1 ATOM 5514 C CA . VAL E 2 101 ? -69.846 -28.843 -1.315 1.00 36.08 ? 308 VAL E CA 1 ATOM 5515 C C . VAL E 2 101 ? -70.327 -29.094 -2.738 1.00 43.40 ? 308 VAL E C 1 ATOM 5516 O O . VAL E 2 101 ? -69.728 -29.881 -3.480 1.00 32.47 ? 308 VAL E O 1 ATOM 5517 C CB . VAL E 2 101 ? -68.986 -27.547 -1.267 1.00 37.88 ? 308 VAL E CB 1 ATOM 5518 C CG1 . VAL E 2 101 ? -68.348 -27.354 0.106 1.00 30.79 ? 308 VAL E CG1 1 ATOM 5519 C CG2 . VAL E 2 101 ? -67.917 -27.541 -2.357 1.00 34.89 ? 308 VAL E CG2 1 ATOM 5520 N N . LEU E 2 102 ? -71.420 -28.434 -3.104 1.00 44.62 ? 309 LEU E N 1 ATOM 5521 C CA . LEU E 2 102 ? -71.874 -28.455 -4.473 1.00 44.83 ? 309 LEU E CA 1 ATOM 5522 C C . LEU E 2 102 ? -70.958 -27.547 -5.272 1.00 42.14 ? 309 LEU E C 1 ATOM 5523 O O . LEU E 2 102 ? -70.516 -26.513 -4.769 1.00 41.10 ? 309 LEU E O 1 ATOM 5524 C CB . LEU E 2 102 ? -73.315 -27.966 -4.573 1.00 45.48 ? 309 LEU E CB 1 ATOM 5525 C CG . LEU E 2 102 ? -74.462 -28.737 -3.917 1.00 50.64 ? 309 LEU E CG 1 ATOM 5526 C CD1 . LEU E 2 102 ? -75.779 -28.229 -4.502 1.00 42.58 ? 309 LEU E CD1 1 ATOM 5527 C CD2 . LEU E 2 102 ? -74.327 -30.247 -4.095 1.00 41.31 ? 309 LEU E CD2 1 ATOM 5528 N N . HIS E 2 103 ? -70.668 -27.949 -6.507 1.00 44.89 ? 310 HIS E N 1 ATOM 5529 C CA . HIS E 2 103 ? -69.877 -27.140 -7.432 1.00 41.96 ? 310 HIS E CA 1 ATOM 5530 C C . HIS E 2 103 ? -70.458 -25.756 -7.568 1.00 45.01 ? 310 HIS E C 1 ATOM 5531 O O . HIS E 2 103 ? -69.772 -24.759 -7.298 1.00 42.34 ? 310 HIS E O 1 ATOM 5532 C CB . HIS E 2 103 ? -69.800 -27.817 -8.790 1.00 43.67 ? 310 HIS E CB 1 ATOM 5533 C CG . HIS E 2 103 ? -69.381 -29.263 -8.725 1.00 50.70 ? 310 HIS E CG 1 ATOM 5534 N ND1 . HIS E 2 103 ? -70.221 -30.243 -8.341 1.00 55.50 ? 310 HIS E ND1 1 ATOM 5535 C CD2 . HIS E 2 103 ? -68.168 -29.877 -9.021 1.00 50.19 ? 310 HIS E CD2 1 ATOM 5536 C CE1 . HIS E 2 103 ? -69.580 -31.422 -8.383 1.00 49.33 ? 310 HIS E CE1 1 ATOM 5537 N NE2 . HIS E 2 103 ? -68.321 -31.196 -8.801 1.00 57.29 ? 310 HIS E NE2 1 ATOM 5538 N N . GLN E 2 104 ? -71.733 -25.690 -7.962 1.00 43.76 ? 311 GLN E N 1 ATOM 5539 C CA . GLN E 2 104 ? -72.454 -24.426 -8.132 1.00 42.53 ? 311 GLN E CA 1 ATOM 5540 C C . GLN E 2 104 ? -72.378 -23.566 -6.872 1.00 39.89 ? 311 GLN E C 1 ATOM 5541 O O . GLN E 2 104 ? -72.004 -22.399 -6.949 1.00 46.79 ? 311 GLN E O 1 ATOM 5542 C CB . GLN E 2 104 ? -73.916 -24.666 -8.524 1.00 39.84 ? 311 GLN E CB 1 ATOM 5543 N N . ASP E 2 105 ? -72.708 -24.152 -5.722 1.00 35.33 ? 312 ASP E N 1 ATOM 5544 C CA . ASP E 2 105 ? -72.634 -23.450 -4.427 1.00 36.52 ? 312 ASP E CA 1 ATOM 5545 C C . ASP E 2 105 ? -71.329 -22.688 -4.239 1.00 40.58 ? 312 ASP E C 1 ATOM 5546 O O . ASP E 2 105 ? -71.340 -21.501 -3.894 1.00 44.96 ? 312 ASP E O 1 ATOM 5547 C CB . ASP E 2 105 ? -72.802 -24.434 -3.270 1.00 36.60 ? 312 ASP E CB 1 ATOM 5548 C CG . ASP E 2 105 ? -74.246 -24.777 -2.991 1.00 43.28 ? 312 ASP E CG 1 ATOM 5549 O OD1 . ASP E 2 105 ? -75.121 -24.467 -3.826 1.00 54.54 ? 312 ASP E OD1 1 ATOM 5550 O OD2 . ASP E 2 105 ? -74.509 -25.359 -1.920 1.00 54.61 ? 312 ASP E OD2 1 ATOM 5551 N N . TRP E 2 106 ? -70.208 -23.379 -4.449 1.00 41.67 ? 313 TRP E N 1 ATOM 5552 C CA . TRP E 2 106 ? -68.889 -22.766 -4.316 1.00 34.38 ? 313 TRP E CA 1 ATOM 5553 C C . TRP E 2 106 ? -68.660 -21.717 -5.370 1.00 38.23 ? 313 TRP E C 1 ATOM 5554 O O . TRP E 2 106 ? -68.165 -20.633 -5.066 1.00 37.17 ? 313 TRP E O 1 ATOM 5555 C CB . TRP E 2 106 ? -67.789 -23.816 -4.384 1.00 34.41 ? 313 TRP E CB 1 ATOM 5556 C CG . TRP E 2 106 ? -66.421 -23.192 -4.329 1.00 28.65 ? 313 TRP E CG 1 ATOM 5557 C CD1 . TRP E 2 106 ? -65.608 -22.812 -5.400 1.00 25.24 ? 313 TRP E CD1 1 ATOM 5558 C CD2 . TRP E 2 106 ? -65.681 -22.809 -3.126 1.00 22.35 ? 313 TRP E CD2 1 ATOM 5559 N NE1 . TRP E 2 106 ? -64.443 -22.248 -4.945 1.00 25.97 ? 313 TRP E NE1 1 ATOM 5560 C CE2 . TRP E 2 106 ? -64.425 -22.218 -3.587 1.00 23.72 ? 313 TRP E CE2 1 ATOM 5561 C CE3 . TRP E 2 106 ? -65.932 -22.890 -1.758 1.00 26.27 ? 313 TRP E CE3 1 ATOM 5562 C CZ2 . TRP E 2 106 ? -63.472 -21.742 -2.705 1.00 25.55 ? 313 TRP E CZ2 1 ATOM 5563 C CZ3 . TRP E 2 106 ? -64.962 -22.415 -0.877 1.00 23.31 ? 313 TRP E CZ3 1 ATOM 5564 C CH2 . TRP E 2 106 ? -63.763 -21.851 -1.338 1.00 24.06 ? 313 TRP E CH2 1 ATOM 5565 N N . LEU E 2 107 ? -69.016 -22.036 -6.615 1.00 34.89 ? 314 LEU E N 1 ATOM 5566 C CA . LEU E 2 107 ? -68.835 -21.123 -7.744 1.00 41.05 ? 314 LEU E CA 1 ATOM 5567 C C . LEU E 2 107 ? -69.728 -19.869 -7.676 1.00 47.62 ? 314 LEU E C 1 ATOM 5568 O O . LEU E 2 107 ? -69.453 -18.874 -8.342 1.00 56.26 ? 314 LEU E O 1 ATOM 5569 C CB . LEU E 2 107 ? -69.018 -21.863 -9.081 1.00 39.02 ? 314 LEU E CB 1 ATOM 5570 C CG . LEU E 2 107 ? -67.969 -22.916 -9.477 1.00 42.90 ? 314 LEU E CG 1 ATOM 5571 C CD1 . LEU E 2 107 ? -68.323 -23.559 -10.814 1.00 44.60 ? 314 LEU E CD1 1 ATOM 5572 C CD2 . LEU E 2 107 ? -66.561 -22.328 -9.536 1.00 41.67 ? 314 LEU E CD2 1 ATOM 5573 N N . ASN E 2 108 ? -70.783 -19.925 -6.867 1.00 50.85 ? 315 ASN E N 1 ATOM 5574 C CA . ASN E 2 108 ? -71.649 -18.768 -6.625 1.00 50.35 ? 315 ASN E CA 1 ATOM 5575 C C . ASN E 2 108 ? -71.227 -17.987 -5.375 1.00 48.04 ? 315 ASN E C 1 ATOM 5576 O O . ASN E 2 108 ? -71.912 -17.058 -4.940 1.00 48.79 ? 315 ASN E O 1 ATOM 5577 C CB . ASN E 2 108 ? -73.118 -19.202 -6.537 1.00 49.55 ? 315 ASN E CB 1 ATOM 5578 C CG . ASN E 2 108 ? -73.634 -19.797 -7.840 1.00 55.90 ? 315 ASN E CG 1 ATOM 5579 O OD1 . ASN E 2 108 ? -73.133 -19.485 -8.925 1.00 62.34 ? 315 ASN E OD1 1 ATOM 5580 N ND2 . ASN E 2 108 ? -74.647 -20.659 -7.739 1.00 49.54 ? 315 ASN E ND2 1 ATOM 5581 N N . GLY E 2 109 ? -70.095 -18.383 -4.804 1.00 38.88 ? 316 GLY E N 1 ATOM 5582 C CA . GLY E 2 109 ? -69.441 -17.609 -3.765 1.00 35.68 ? 316 GLY E CA 1 ATOM 5583 C C . GLY E 2 109 ? -70.104 -17.687 -2.410 1.00 37.20 ? 316 GLY E C 1 ATOM 5584 O O . GLY E 2 109 ? -70.067 -16.726 -1.646 1.00 47.28 ? 316 GLY E O 1 ATOM 5585 N N . LYS E 2 110 ? -70.712 -18.828 -2.104 1.00 39.35 ? 317 LYS E N 1 ATOM 5586 C CA . LYS E 2 110 ? -71.275 -19.043 -0.782 1.00 43.37 ? 317 LYS E CA 1 ATOM 5587 C C . LYS E 2 110 ? -70.144 -19.155 0.232 1.00 47.14 ? 317 LYS E C 1 ATOM 5588 O O . LYS E 2 110 ? -69.048 -19.623 -0.090 1.00 48.82 ? 317 LYS E O 1 ATOM 5589 C CB . LYS E 2 110 ? -72.186 -20.270 -0.764 1.00 51.23 ? 317 LYS E CB 1 ATOM 5590 C CG . LYS E 2 110 ? -73.595 -19.980 -1.261 1.00 58.05 ? 317 LYS E CG 1 ATOM 5591 C CD . LYS E 2 110 ? -74.268 -21.229 -1.808 1.00 58.44 ? 317 LYS E CD 1 ATOM 5592 C CE . LYS E 2 110 ? -75.782 -21.080 -1.865 1.00 52.29 ? 317 LYS E CE 1 ATOM 5593 N NZ . LYS E 2 110 ? -76.365 -21.093 -0.494 1.00 61.43 ? 317 LYS E NZ 1 ATOM 5594 N N . GLU E 2 111 ? -70.408 -18.693 1.447 1.00 43.77 ? 318 GLU E N 1 ATOM 5595 C CA . GLU E 2 111 ? -69.382 -18.613 2.474 1.00 42.49 ? 318 GLU E CA 1 ATOM 5596 C C . GLU E 2 111 ? -69.446 -19.831 3.371 1.00 39.89 ? 318 GLU E C 1 ATOM 5597 O O . GLU E 2 111 ? -70.513 -20.185 3.878 1.00 35.19 ? 318 GLU E O 1 ATOM 5598 C CB . GLU E 2 111 ? -69.532 -17.325 3.298 1.00 42.98 ? 318 GLU E CB 1 ATOM 5599 C CG . GLU E 2 111 ? -69.416 -16.051 2.470 1.00 48.00 ? 318 GLU E CG 1 ATOM 5600 C CD . GLU E 2 111 ? -68.877 -14.873 3.257 1.00 58.61 ? 318 GLU E CD 1 ATOM 5601 O OE1 . GLU E 2 111 ? -69.417 -14.567 4.345 1.00 61.35 ? 318 GLU E OE1 1 ATOM 5602 O OE2 . GLU E 2 111 ? -67.912 -14.242 2.778 1.00 61.55 ? 318 GLU E OE2 1 ATOM 5603 N N . TYR E 2 112 ? -68.298 -20.476 3.560 1.00 40.05 ? 319 TYR E N 1 ATOM 5604 C CA . TYR E 2 112 ? -68.216 -21.630 4.440 1.00 31.05 ? 319 TYR E CA 1 ATOM 5605 C C . TYR E 2 112 ? -67.464 -21.292 5.726 1.00 30.74 ? 319 TYR E C 1 ATOM 5606 O O . TYR E 2 112 ? -66.308 -20.871 5.690 1.00 35.51 ? 319 TYR E O 1 ATOM 5607 C CB . TYR E 2 112 ? -67.608 -22.811 3.705 1.00 24.90 ? 319 TYR E CB 1 ATOM 5608 C CG . TYR E 2 112 ? -68.411 -23.214 2.473 1.00 27.68 ? 319 TYR E CG 1 ATOM 5609 C CD1 . TYR E 2 112 ? -68.218 -22.566 1.247 1.00 24.15 ? 319 TYR E CD1 1 ATOM 5610 C CD2 . TYR E 2 112 ? -69.374 -24.234 2.535 1.00 26.05 ? 319 TYR E CD2 1 ATOM 5611 C CE1 . TYR E 2 112 ? -68.951 -22.922 0.121 1.00 27.45 ? 319 TYR E CE1 1 ATOM 5612 C CE2 . TYR E 2 112 ? -70.109 -24.599 1.409 1.00 28.25 ? 319 TYR E CE2 1 ATOM 5613 C CZ . TYR E 2 112 ? -69.890 -23.942 0.203 1.00 32.27 ? 319 TYR E CZ 1 ATOM 5614 O OH . TYR E 2 112 ? -70.604 -24.290 -0.930 1.00 36.32 ? 319 TYR E OH 1 ATOM 5615 N N . LYS E 2 113 ? -68.144 -21.463 6.855 1.00 34.58 ? 320 LYS E N 1 ATOM 5616 C CA . LYS E 2 113 ? -67.582 -21.145 8.167 1.00 35.53 ? 320 LYS E CA 1 ATOM 5617 C C . LYS E 2 113 ? -67.403 -22.402 9.010 1.00 37.51 ? 320 LYS E C 1 ATOM 5618 O O . LYS E 2 113 ? -68.299 -23.238 9.097 1.00 36.21 ? 320 LYS E O 1 ATOM 5619 C CB . LYS E 2 113 ? -68.485 -20.158 8.907 1.00 34.53 ? 320 LYS E CB 1 ATOM 5620 C CG . LYS E 2 113 ? -67.906 -19.652 10.225 1.00 43.04 ? 320 LYS E CG 1 ATOM 5621 C CD . LYS E 2 113 ? -69.004 -19.272 11.208 1.00 50.65 ? 320 LYS E CD 1 ATOM 5622 C CE . LYS E 2 113 ? -69.753 -18.009 10.797 1.00 51.16 ? 320 LYS E CE 1 ATOM 5623 N NZ . LYS E 2 113 ? -70.784 -17.647 11.809 1.00 62.07 ? 320 LYS E NZ 1 ATOM 5624 N N . CYS E 2 114 ? -66.239 -22.509 9.637 1.00 37.81 ? 321 CYS E N 1 ATOM 5625 C CA . CYS E 2 114 ? -65.914 -23.612 10.511 1.00 41.65 ? 321 CYS E CA 1 ATOM 5626 C C . CYS E 2 114 ? -65.683 -23.073 11.926 1.00 42.89 ? 321 CYS E C 1 ATOM 5627 O O . CYS E 2 114 ? -64.744 -22.307 12.153 1.00 41.09 ? 321 CYS E O 1 ATOM 5628 C CB . CYS E 2 114 ? -64.649 -24.319 9.996 1.00 49.83 ? 321 CYS E CB 1 ATOM 5629 S SG . CYS E 2 114 ? -64.129 -25.740 10.985 1.00 55.28 ? 321 CYS E SG 1 ATOM 5630 N N . LYS E 2 115 ? -66.543 -23.468 12.865 1.00 47.54 ? 322 LYS E N 1 ATOM 5631 C CA . LYS E 2 115 ? -66.361 -23.139 14.280 1.00 45.27 ? 322 LYS E CA 1 ATOM 5632 C C . LYS E 2 115 ? -65.772 -24.343 15.015 1.00 49.29 ? 322 LYS E C 1 ATOM 5633 O O . LYS E 2 115 ? -66.321 -25.444 14.952 1.00 47.83 ? 322 LYS E O 1 ATOM 5634 C CB . LYS E 2 115 ? -67.690 -22.725 14.914 1.00 45.64 ? 322 LYS E CB 1 ATOM 5635 C CG . LYS E 2 115 ? -67.547 -22.097 16.297 1.00 50.04 ? 322 LYS E CG 1 ATOM 5636 C CD . LYS E 2 115 ? -68.866 -21.530 16.808 1.00 50.09 ? 322 LYS E CD 1 ATOM 5637 C CE . LYS E 2 115 ? -69.680 -22.575 17.559 1.00 47.79 ? 322 LYS E CE 1 ATOM 5638 N NZ . LYS E 2 115 ? -71.052 -22.095 17.881 1.00 43.26 ? 322 LYS E NZ 1 ATOM 5639 N N . VAL E 2 116 ? -64.651 -24.129 15.699 1.00 47.56 ? 323 VAL E N 1 ATOM 5640 C CA . VAL E 2 116 ? -63.960 -25.207 16.397 1.00 51.17 ? 323 VAL E CA 1 ATOM 5641 C C . VAL E 2 116 ? -64.021 -24.996 17.910 1.00 59.33 ? 323 VAL E C 1 ATOM 5642 O O . VAL E 2 116 ? -63.568 -23.973 18.420 1.00 60.95 ? 323 VAL E O 1 ATOM 5643 C CB . VAL E 2 116 ? -62.490 -25.350 15.923 1.00 49.52 ? 323 VAL E CB 1 ATOM 5644 C CG1 . VAL E 2 116 ? -61.701 -26.249 16.863 1.00 48.33 ? 323 VAL E CG1 1 ATOM 5645 C CG2 . VAL E 2 116 ? -62.430 -25.895 14.502 1.00 48.09 ? 323 VAL E CG2 1 ATOM 5646 N N . SER E 2 117 ? -64.587 -25.969 18.617 1.00 64.64 ? 324 SER E N 1 ATOM 5647 C CA . SER E 2 117 ? -64.677 -25.906 20.071 1.00 59.01 ? 324 SER E CA 1 ATOM 5648 C C . SER E 2 117 ? -63.882 -27.024 20.738 1.00 59.87 ? 324 SER E C 1 ATOM 5649 O O . SER E 2 117 ? -63.896 -28.177 20.291 1.00 56.50 ? 324 SER E O 1 ATOM 5650 C CB . SER E 2 117 ? -66.135 -25.927 20.527 1.00 61.28 ? 324 SER E CB 1 ATOM 5651 O OG . SER E 2 117 ? -66.774 -24.698 20.233 1.00 67.42 ? 324 SER E OG 1 ATOM 5652 N N . ASN E 2 118 ? -63.193 -26.658 21.813 1.00 62.41 ? 325 ASN E N 1 ATOM 5653 C CA . ASN E 2 118 ? -62.300 -27.547 22.541 1.00 60.66 ? 325 ASN E CA 1 ATOM 5654 C C . ASN E 2 118 ? -62.073 -26.969 23.935 1.00 67.97 ? 325 ASN E C 1 ATOM 5655 O O . ASN E 2 118 ? -62.134 -25.751 24.118 1.00 66.27 ? 325 ASN E O 1 ATOM 5656 C CB . ASN E 2 118 ? -60.974 -27.677 21.784 1.00 61.97 ? 325 ASN E CB 1 ATOM 5657 C CG . ASN E 2 118 ? -59.957 -28.534 22.512 1.00 68.15 ? 325 ASN E CG 1 ATOM 5658 O OD1 . ASN E 2 118 ? -59.035 -28.015 23.145 1.00 61.22 ? 325 ASN E OD1 1 ATOM 5659 N ND2 . ASN E 2 118 ? -60.119 -29.854 22.429 1.00 62.82 ? 325 ASN E ND2 1 ATOM 5660 N N . LYS E 2 119 ? -61.816 -27.842 24.908 1.00 71.20 ? 326 LYS E N 1 ATOM 5661 C CA . LYS E 2 119 ? -61.642 -27.438 26.308 1.00 69.76 ? 326 LYS E CA 1 ATOM 5662 C C . LYS E 2 119 ? -60.417 -26.549 26.550 1.00 76.07 ? 326 LYS E C 1 ATOM 5663 O O . LYS E 2 119 ? -60.432 -25.711 27.453 1.00 82.43 ? 326 LYS E O 1 ATOM 5664 C CB . LYS E 2 119 ? -61.600 -28.668 27.223 1.00 63.16 ? 326 LYS E CB 1 ATOM 5665 N N . ALA E 2 120 ? -59.369 -26.720 25.742 1.00 77.27 ? 327 ALA E N 1 ATOM 5666 C CA . ALA E 2 120 ? -58.161 -25.886 25.842 1.00 65.36 ? 327 ALA E CA 1 ATOM 5667 C C . ALA E 2 120 ? -58.311 -24.519 25.159 1.00 69.77 ? 327 ALA E C 1 ATOM 5668 O O . ALA E 2 120 ? -57.361 -23.731 25.106 1.00 76.57 ? 327 ALA E O 1 ATOM 5669 C CB . ALA E 2 120 ? -56.952 -26.629 25.293 1.00 54.42 ? 327 ALA E CB 1 ATOM 5670 N N . LEU E 2 121 ? -59.508 -24.245 24.644 1.00 63.00 ? 328 LEU E N 1 ATOM 5671 C CA . LEU E 2 121 ? -59.817 -22.974 24.000 1.00 61.03 ? 328 LEU E CA 1 ATOM 5672 C C . LEU E 2 121 ? -60.616 -22.054 24.915 1.00 69.07 ? 328 LEU E C 1 ATOM 5673 O O . LEU E 2 121 ? -61.636 -22.473 25.464 1.00 70.10 ? 328 LEU E O 1 ATOM 5674 C CB . LEU E 2 121 ? -60.599 -23.215 22.706 1.00 64.19 ? 328 LEU E CB 1 ATOM 5675 C CG . LEU E 2 121 ? -59.918 -22.982 21.352 1.00 64.23 ? 328 LEU E CG 1 ATOM 5676 C CD1 . LEU E 2 121 ? -58.407 -23.166 21.402 1.00 57.65 ? 328 LEU E CD1 1 ATOM 5677 C CD2 . LEU E 2 121 ? -60.553 -23.857 20.280 1.00 61.10 ? 328 LEU E CD2 1 ATOM 5678 N N . PRO E 2 122 ? -60.165 -20.789 25.072 1.00 75.83 ? 329 PRO E N 1 ATOM 5679 C CA . PRO E 2 122 ? -60.894 -19.817 25.896 1.00 71.94 ? 329 PRO E CA 1 ATOM 5680 C C . PRO E 2 122 ? -62.287 -19.543 25.328 1.00 70.85 ? 329 PRO E C 1 ATOM 5681 O O . PRO E 2 122 ? -63.245 -19.356 26.084 1.00 70.06 ? 329 PRO E O 1 ATOM 5682 C CB . PRO E 2 122 ? -60.017 -18.558 25.820 1.00 79.39 ? 329 PRO E CB 1 ATOM 5683 C CG . PRO E 2 122 ? -59.195 -18.722 24.581 1.00 74.09 ? 329 PRO E CG 1 ATOM 5684 C CD . PRO E 2 122 ? -58.959 -20.198 24.456 1.00 79.78 ? 329 PRO E CD 1 ATOM 5685 N N . ALA E 2 123 ? -62.375 -19.531 24.001 1.00 63.09 ? 330 ALA E N 1 ATOM 5686 C CA . ALA E 2 123 ? -63.625 -19.381 23.269 1.00 66.11 ? 330 ALA E CA 1 ATOM 5687 C C . ALA E 2 123 ? -63.446 -20.039 21.899 1.00 67.02 ? 330 ALA E C 1 ATOM 5688 O O . ALA E 2 123 ? -62.318 -20.123 21.402 1.00 65.77 ? 330 ALA E O 1 ATOM 5689 C CB . ALA E 2 123 ? -63.978 -17.907 23.117 1.00 71.12 ? 330 ALA E CB 1 ATOM 5690 N N . PRO E 2 124 ? -64.547 -20.517 21.286 1.00 66.53 ? 331 PRO E N 1 ATOM 5691 C CA . PRO E 2 124 ? -64.427 -21.192 19.992 1.00 64.97 ? 331 PRO E CA 1 ATOM 5692 C C . PRO E 2 124 ? -63.750 -20.330 18.927 1.00 59.86 ? 331 PRO E C 1 ATOM 5693 O O . PRO E 2 124 ? -64.083 -19.155 18.783 1.00 74.15 ? 331 PRO E O 1 ATOM 5694 C CB . PRO E 2 124 ? -65.886 -21.463 19.602 1.00 65.31 ? 331 PRO E CB 1 ATOM 5695 C CG . PRO E 2 124 ? -66.615 -21.530 20.896 1.00 67.19 ? 331 PRO E CG 1 ATOM 5696 C CD . PRO E 2 124 ? -65.941 -20.514 21.772 1.00 68.94 ? 331 PRO E CD 1 ATOM 5697 N N . ILE E 2 125 ? -62.795 -20.913 18.206 1.00 62.09 ? 332 ILE E N 1 ATOM 5698 C CA . ILE E 2 125 ? -62.176 -20.242 17.067 1.00 60.56 ? 332 ILE E CA 1 ATOM 5699 C C . ILE E 2 125 ? -63.022 -20.507 15.834 1.00 58.45 ? 332 ILE E C 1 ATOM 5700 O O . ILE E 2 125 ? -63.447 -21.639 15.594 1.00 62.93 ? 332 ILE E O 1 ATOM 5701 C CB . ILE E 2 125 ? -60.743 -20.741 16.781 1.00 59.54 ? 332 ILE E CB 1 ATOM 5702 C CG1 . ILE E 2 125 ? -59.905 -20.796 18.061 1.00 54.96 ? 332 ILE E CG1 1 ATOM 5703 C CG2 . ILE E 2 125 ? -60.071 -19.862 15.730 1.00 66.02 ? 332 ILE E CG2 1 ATOM 5704 C CD1 . ILE E 2 125 ? -58.534 -21.419 17.873 1.00 56.44 ? 332 ILE E CD1 1 ATOM 5705 N N . GLU E 2 126 ? -63.262 -19.451 15.063 1.00 56.48 ? 333 GLU E N 1 ATOM 5706 C CA . GLU E 2 126 ? -63.957 -19.553 13.789 1.00 51.42 ? 333 GLU E CA 1 ATOM 5707 C C . GLU E 2 126 ? -63.066 -19.022 12.669 1.00 54.07 ? 333 GLU E C 1 ATOM 5708 O O . GLU E 2 126 ? -62.332 -18.052 12.855 1.00 55.08 ? 333 GLU E O 1 ATOM 5709 C CB . GLU E 2 126 ? -65.272 -18.763 13.815 1.00 53.18 ? 333 GLU E CB 1 ATOM 5710 C CG . GLU E 2 126 ? -66.179 -19.072 14.998 1.00 67.71 ? 333 GLU E CG 1 ATOM 5711 C CD . GLU E 2 126 ? -67.561 -18.449 14.880 1.00 75.53 ? 333 GLU E CD 1 ATOM 5712 O OE1 . GLU E 2 126 ? -68.228 -18.295 15.922 1.00 75.10 ? 333 GLU E OE1 1 ATOM 5713 O OE2 . GLU E 2 126 ? -67.989 -18.118 13.754 1.00 76.63 ? 333 GLU E OE2 1 ATOM 5714 N N . LYS E 2 127 ? -63.126 -19.683 11.516 1.00 47.34 ? 334 LYS E N 1 ATOM 5715 C CA . LYS E 2 127 ? -62.507 -19.192 10.288 1.00 45.58 ? 334 LYS E CA 1 ATOM 5716 C C . LYS E 2 127 ? -63.531 -19.316 9.178 1.00 44.69 ? 334 LYS E C 1 ATOM 5717 O O . LYS E 2 127 ? -64.412 -20.178 9.221 1.00 45.54 ? 334 LYS E O 1 ATOM 5718 C CB . LYS E 2 127 ? -61.255 -19.995 9.918 1.00 49.80 ? 334 LYS E CB 1 ATOM 5719 C CG . LYS E 2 127 ? -60.172 -20.052 10.990 1.00 52.61 ? 334 LYS E CG 1 ATOM 5720 C CD . LYS E 2 127 ? -59.259 -18.836 11.000 1.00 53.39 ? 334 LYS E CD 1 ATOM 5721 C CE . LYS E 2 127 ? -58.632 -18.680 12.380 1.00 63.34 ? 334 LYS E CE 1 ATOM 5722 N NZ . LYS E 2 127 ? -57.449 -17.781 12.390 1.00 67.86 ? 334 LYS E NZ 1 ATOM 5723 N N . THR E 2 128 ? -63.410 -18.444 8.187 1.00 44.05 ? 335 THR E N 1 ATOM 5724 C CA . THR E 2 128 ? -64.355 -18.383 7.087 1.00 41.32 ? 335 THR E CA 1 ATOM 5725 C C . THR E 2 128 ? -63.548 -18.230 5.809 1.00 39.75 ? 335 THR E C 1 ATOM 5726 O O . THR E 2 128 ? -62.525 -17.555 5.789 1.00 50.33 ? 335 THR E O 1 ATOM 5727 C CB . THR E 2 128 ? -65.315 -17.173 7.244 1.00 46.95 ? 335 THR E CB 1 ATOM 5728 O OG1 . THR E 2 128 ? -65.866 -17.159 8.569 1.00 54.30 ? 335 THR E OG1 1 ATOM 5729 C CG2 . THR E 2 128 ? -66.455 -17.216 6.220 1.00 43.72 ? 335 THR E CG2 1 ATOM 5730 N N . ILE E 2 129 ? -64.011 -18.877 4.751 1.00 36.78 ? 336 ILE E N 1 ATOM 5731 C CA . ILE E 2 129 ? -63.418 -18.749 3.431 1.00 39.35 ? 336 ILE E CA 1 ATOM 5732 C C . ILE E 2 129 ? -64.523 -18.876 2.398 1.00 38.01 ? 336 ILE E C 1 ATOM 5733 O O . ILE E 2 129 ? -65.654 -19.256 2.727 1.00 40.98 ? 336 ILE E O 1 ATOM 5734 C CB . ILE E 2 129 ? -62.330 -19.830 3.144 1.00 48.28 ? 336 ILE E CB 1 ATOM 5735 C CG1 . ILE E 2 129 ? -62.899 -21.249 3.259 1.00 42.86 ? 336 ILE E CG1 1 ATOM 5736 C CG2 . ILE E 2 129 ? -61.098 -19.645 4.027 1.00 51.34 ? 336 ILE E CG2 1 ATOM 5737 C CD1 . ILE E 2 129 ? -63.116 -21.931 1.927 1.00 46.64 ? 336 ILE E CD1 1 ATOM 5738 N N . SER E 2 130 ? -64.180 -18.559 1.154 1.00 31.91 ? 337 SER E N 1 ATOM 5739 C CA . SER E 2 130 ? -65.057 -18.739 0.003 1.00 32.60 ? 337 SER E CA 1 ATOM 5740 C C . SER E 2 130 ? -64.256 -18.374 -1.227 1.00 29.98 ? 337 SER E C 1 ATOM 5741 O O . SER E 2 130 ? -63.113 -17.927 -1.125 1.00 35.98 ? 337 SER E O 1 ATOM 5742 C CB . SER E 2 130 ? -66.275 -17.820 0.101 1.00 43.04 ? 337 SER E CB 1 ATOM 5743 O OG . SER E 2 130 ? -65.879 -16.462 0.046 1.00 47.97 ? 337 SER E OG 1 ATOM 5744 N N . LYS E 2 131 ? -64.849 -18.558 -2.397 1.00 35.90 ? 338 LYS E N 1 ATOM 5745 C CA . LYS E 2 131 ? -64.225 -18.147 -3.644 1.00 33.55 ? 338 LYS E CA 1 ATOM 5746 C C . LYS E 2 131 ? -63.825 -16.659 -3.577 1.00 41.00 ? 338 LYS E C 1 ATOM 5747 O O . LYS E 2 131 ? -64.431 -15.880 -2.832 1.00 40.56 ? 338 LYS E O 1 ATOM 5748 C CB . LYS E 2 131 ? -65.219 -18.375 -4.773 1.00 39.41 ? 338 LYS E CB 1 ATOM 5749 C CG . LYS E 2 131 ? -64.601 -18.472 -6.153 1.00 43.73 ? 338 LYS E CG 1 ATOM 5750 C CD . LYS E 2 131 ? -65.682 -18.572 -7.215 1.00 49.20 ? 338 LYS E CD 1 ATOM 5751 C CE . LYS E 2 131 ? -66.459 -17.275 -7.353 1.00 46.11 ? 338 LYS E CE 1 ATOM 5752 N NZ . LYS E 2 131 ? -67.185 -17.279 -8.648 1.00 50.16 ? 338 LYS E NZ 1 ATOM 5753 N N . ALA E 2 132 ? -62.807 -16.259 -4.337 1.00 36.95 ? 339 ALA E N 1 ATOM 5754 C CA . ALA E 2 132 ? -62.433 -14.846 -4.374 1.00 42.08 ? 339 ALA E CA 1 ATOM 5755 C C . ALA E 2 132 ? -63.562 -14.035 -5.010 1.00 40.47 ? 339 ALA E C 1 ATOM 5756 O O . ALA E 2 132 ? -64.239 -14.510 -5.916 1.00 37.00 ? 339 ALA E O 1 ATOM 5757 C CB . ALA E 2 132 ? -61.118 -14.642 -5.108 1.00 34.30 ? 339 ALA E CB 1 ATOM 5758 N N . LYS E 2 133 ? -63.776 -12.822 -4.512 1.00 45.34 ? 340 LYS E N 1 ATOM 5759 C CA . LYS E 2 133 ? -64.913 -12.012 -4.946 1.00 42.45 ? 340 LYS E CA 1 ATOM 5760 C C . LYS E 2 133 ? -64.630 -11.197 -6.207 1.00 40.70 ? 340 LYS E C 1 ATOM 5761 O O . LYS E 2 133 ? -63.518 -10.714 -6.414 1.00 44.87 ? 340 LYS E O 1 ATOM 5762 C CB . LYS E 2 133 ? -65.384 -11.098 -3.813 1.00 45.93 ? 340 LYS E CB 1 ATOM 5763 C CG . LYS E 2 133 ? -65.609 -11.827 -2.494 1.00 57.42 ? 340 LYS E CG 1 ATOM 5764 C CD . LYS E 2 133 ? -66.945 -11.482 -1.859 1.00 66.55 ? 340 LYS E CD 1 ATOM 5765 C CE . LYS E 2 133 ? -68.072 -12.328 -2.439 1.00 74.10 ? 340 LYS E CE 1 ATOM 5766 N NZ . LYS E 2 133 ? -69.321 -12.236 -1.630 1.00 65.55 ? 340 LYS E NZ 1 ATOM 5767 N N . GLY E 2 134 ? -65.652 -11.047 -7.041 1.00 37.41 ? 341 GLY E N 1 ATOM 5768 C CA . GLY E 2 134 ? -65.575 -10.180 -8.210 1.00 33.53 ? 341 GLY E CA 1 ATOM 5769 C C . GLY E 2 134 ? -66.110 -10.864 -9.453 1.00 30.97 ? 341 GLY E C 1 ATOM 5770 O O . GLY E 2 134 ? -66.055 -12.081 -9.569 1.00 28.68 ? 341 GLY E O 1 ATOM 5771 N N . GLN E 2 135 ? -66.626 -10.081 -10.388 1.00 30.81 ? 342 GLN E N 1 ATOM 5772 C CA . GLN E 2 135 ? -67.207 -10.656 -11.590 1.00 37.41 ? 342 GLN E CA 1 ATOM 5773 C C . GLN E 2 135 ? -66.224 -11.570 -12.327 1.00 35.59 ? 342 GLN E C 1 ATOM 5774 O O . GLN E 2 135 ? -65.136 -11.132 -12.711 1.00 42.65 ? 342 GLN E O 1 ATOM 5775 C CB . GLN E 2 135 ? -67.716 -9.566 -12.522 1.00 37.54 ? 342 GLN E CB 1 ATOM 5776 C CG . GLN E 2 135 ? -68.213 -10.095 -13.857 1.00 41.53 ? 342 GLN E CG 1 ATOM 5777 C CD . GLN E 2 135 ? -68.820 -9.007 -14.701 1.00 51.61 ? 342 GLN E CD 1 ATOM 5778 O OE1 . GLN E 2 135 ? -68.809 -7.836 -14.313 1.00 49.22 ? 342 GLN E OE1 1 ATOM 5779 N NE2 . GLN E 2 135 ? -69.352 -9.379 -15.866 1.00 51.27 ? 342 GLN E NE2 1 ATOM 5780 N N . PRO E 2 136 ? -66.605 -12.843 -12.519 1.00 33.60 ? 343 PRO E N 1 ATOM 5781 C CA . PRO E 2 136 ? -65.783 -13.753 -13.312 1.00 33.16 ? 343 PRO E CA 1 ATOM 5782 C C . PRO E 2 136 ? -65.582 -13.238 -14.737 1.00 38.51 ? 343 PRO E C 1 ATOM 5783 O O . PRO E 2 136 ? -66.510 -12.693 -15.337 1.00 39.71 ? 343 PRO E O 1 ATOM 5784 C CB . PRO E 2 136 ? -66.597 -15.058 -13.323 1.00 34.40 ? 343 PRO E CB 1 ATOM 5785 C CG . PRO E 2 136 ? -67.509 -14.963 -12.136 1.00 37.51 ? 343 PRO E CG 1 ATOM 5786 C CD . PRO E 2 136 ? -67.815 -13.502 -11.984 1.00 32.74 ? 343 PRO E CD 1 ATOM 5787 N N . ARG E 2 137 ? -64.367 -13.415 -15.254 1.00 39.79 ? 344 ARG E N 1 ATOM 5788 C CA . ARG E 2 137 ? -64.006 -13.020 -16.611 1.00 36.54 ? 344 ARG E CA 1 ATOM 5789 C C . ARG E 2 137 ? -63.406 -14.190 -17.381 1.00 41.23 ? 344 ARG E C 1 ATOM 5790 O O . ARG E 2 137 ? -62.630 -14.983 -16.835 1.00 42.89 ? 344 ARG E O 1 ATOM 5791 C CB . ARG E 2 137 ? -63.017 -11.861 -16.584 1.00 32.38 ? 344 ARG E CB 1 ATOM 5792 C CG . ARG E 2 137 ? -63.659 -10.487 -16.460 1.00 33.56 ? 344 ARG E CG 1 ATOM 5793 C CD . ARG E 2 137 ? -62.622 -9.376 -16.617 1.00 42.02 ? 344 ARG E CD 1 ATOM 5794 N NE . ARG E 2 137 ? -62.035 -9.356 -17.960 1.00 40.28 ? 344 ARG E NE 1 ATOM 5795 C CZ . ARG E 2 137 ? -61.147 -8.460 -18.381 1.00 43.68 ? 344 ARG E CZ 1 ATOM 5796 N NH1 . ARG E 2 137 ? -60.716 -7.492 -17.568 1.00 38.14 ? 344 ARG E NH1 1 ATOM 5797 N NH2 . ARG E 2 137 ? -60.685 -8.535 -19.623 1.00 39.14 ? 344 ARG E NH2 1 ATOM 5798 N N . GLU E 2 138 ? -63.766 -14.275 -18.657 1.00 45.10 ? 345 GLU E N 1 ATOM 5799 C CA . GLU E 2 138 ? -63.417 -15.409 -19.503 1.00 42.37 ? 345 GLU E CA 1 ATOM 5800 C C . GLU E 2 138 ? -61.959 -15.363 -19.978 1.00 44.86 ? 345 GLU E C 1 ATOM 5801 O O . GLU E 2 138 ? -61.506 -14.336 -20.490 1.00 47.19 ? 345 GLU E O 1 ATOM 5802 C CB . GLU E 2 138 ? -64.371 -15.465 -20.698 1.00 42.36 ? 345 GLU E CB 1 ATOM 5803 C CG . GLU E 2 138 ? -64.145 -16.641 -21.635 1.00 46.25 ? 345 GLU E CG 1 ATOM 5804 C CD . GLU E 2 138 ? -64.841 -16.465 -22.970 1.00 48.43 ? 345 GLU E CD 1 ATOM 5805 O OE1 . GLU E 2 138 ? -65.567 -15.464 -23.147 1.00 49.41 ? 345 GLU E OE1 1 ATOM 5806 O OE2 . GLU E 2 138 ? -64.662 -17.333 -23.846 1.00 52.95 ? 345 GLU E OE2 1 ATOM 5807 N N . PRO E 2 139 ? -61.222 -16.482 -19.810 1.00 43.74 ? 346 PRO E N 1 ATOM 5808 C CA . PRO E 2 139 ? -59.849 -16.609 -20.296 1.00 44.70 ? 346 PRO E CA 1 ATOM 5809 C C . PRO E 2 139 ? -59.734 -16.485 -21.808 1.00 46.22 ? 346 PRO E C 1 ATOM 5810 O O . PRO E 2 139 ? -60.462 -17.152 -22.542 1.00 55.92 ? 346 PRO E O 1 ATOM 5811 C CB . PRO E 2 139 ? -59.457 -18.031 -19.889 1.00 41.40 ? 346 PRO E CB 1 ATOM 5812 C CG . PRO E 2 139 ? -60.332 -18.355 -18.738 1.00 46.27 ? 346 PRO E CG 1 ATOM 5813 C CD . PRO E 2 139 ? -61.619 -17.624 -18.964 1.00 47.27 ? 346 PRO E CD 1 ATOM 5814 N N . GLN E 2 140 ? -58.825 -15.628 -22.260 1.00 42.86 ? 347 GLN E N 1 ATOM 5815 C CA . GLN E 2 140 ? -58.415 -15.614 -23.654 1.00 42.35 ? 347 GLN E CA 1 ATOM 5816 C C . GLN E 2 140 ? -57.222 -16.553 -23.780 1.00 40.50 ? 347 GLN E C 1 ATOM 5817 O O . GLN E 2 140 ? -56.194 -16.363 -23.119 1.00 35.31 ? 347 GLN E O 1 ATOM 5818 C CB . GLN E 2 140 ? -58.025 -14.207 -24.090 1.00 46.13 ? 347 GLN E CB 1 ATOM 5819 C CG . GLN E 2 140 ? -59.137 -13.173 -24.001 1.00 44.51 ? 347 GLN E CG 1 ATOM 5820 C CD . GLN E 2 140 ? -58.587 -11.763 -23.875 1.00 52.00 ? 347 GLN E CD 1 ATOM 5821 O OE1 . GLN E 2 140 ? -58.826 -11.079 -22.878 1.00 51.59 ? 347 GLN E OE1 1 ATOM 5822 N NE2 . GLN E 2 140 ? -57.827 -11.328 -24.877 1.00 52.07 ? 347 GLN E NE2 1 ATOM 5823 N N . VAL E 2 141 ? -57.371 -17.574 -24.618 1.00 37.53 ? 348 VAL E N 1 ATOM 5824 C CA . VAL E 2 141 ? -56.353 -18.604 -24.768 1.00 35.85 ? 348 VAL E CA 1 ATOM 5825 C C . VAL E 2 141 ? -55.710 -18.477 -26.144 1.00 39.66 ? 348 VAL E C 1 ATOM 5826 O O . VAL E 2 141 ? -56.380 -18.621 -27.170 1.00 41.15 ? 348 VAL E O 1 ATOM 5827 C CB . VAL E 2 141 ? -56.928 -20.028 -24.549 1.00 35.10 ? 348 VAL E CB 1 ATOM 5828 C CG1 . VAL E 2 141 ? -55.820 -21.071 -24.551 1.00 37.12 ? 348 VAL E CG1 1 ATOM 5829 C CG2 . VAL E 2 141 ? -57.686 -20.108 -23.237 1.00 31.02 ? 348 VAL E CG2 1 ATOM 5830 N N . TYR E 2 142 ? -54.408 -18.193 -26.147 1.00 35.73 ? 349 TYR E N 1 ATOM 5831 C CA . TYR E 2 142 ? -53.658 -17.978 -27.371 1.00 35.33 ? 349 TYR E CA 1 ATOM 5832 C C . TYR E 2 142 ? -52.412 -18.851 -27.417 1.00 47.38 ? 349 TYR E C 1 ATOM 5833 O O . TYR E 2 142 ? -51.538 -18.769 -26.542 1.00 53.21 ? 349 TYR E O 1 ATOM 5834 C CB . TYR E 2 142 ? -53.246 -16.511 -27.501 1.00 36.59 ? 349 TYR E CB 1 ATOM 5835 C CG . TYR E 2 142 ? -54.375 -15.510 -27.408 1.00 38.72 ? 349 TYR E CG 1 ATOM 5836 C CD1 . TYR E 2 142 ? -55.373 -15.449 -28.392 1.00 37.64 ? 349 TYR E CD1 1 ATOM 5837 C CD2 . TYR E 2 142 ? -54.439 -14.606 -26.347 1.00 32.29 ? 349 TYR E CD2 1 ATOM 5838 C CE1 . TYR E 2 142 ? -56.405 -14.520 -28.311 1.00 31.66 ? 349 TYR E CE1 1 ATOM 5839 C CE2 . TYR E 2 142 ? -55.466 -13.672 -26.262 1.00 35.34 ? 349 TYR E CE2 1 ATOM 5840 C CZ . TYR E 2 142 ? -56.443 -13.632 -27.243 1.00 34.24 ? 349 TYR E CZ 1 ATOM 5841 O OH . TYR E 2 142 ? -57.456 -12.701 -27.158 1.00 37.66 ? 349 TYR E OH 1 ATOM 5842 N N . THR E 2 143 ? -52.338 -19.691 -28.442 1.00 43.81 ? 350 THR E N 1 ATOM 5843 C CA . THR E 2 143 ? -51.157 -20.500 -28.690 1.00 46.68 ? 350 THR E CA 1 ATOM 5844 C C . THR E 2 143 ? -50.173 -19.724 -29.566 1.00 46.10 ? 350 THR E C 1 ATOM 5845 O O . THR E 2 143 ? -50.571 -19.053 -30.524 1.00 47.56 ? 350 THR E O 1 ATOM 5846 C CB . THR E 2 143 ? -51.526 -21.839 -29.351 1.00 48.44 ? 350 THR E CB 1 ATOM 5847 O OG1 . THR E 2 143 ? -52.371 -21.593 -30.485 1.00 55.30 ? 350 THR E OG1 1 ATOM 5848 C CG2 . THR E 2 143 ? -52.257 -22.725 -28.358 1.00 47.68 ? 350 THR E CG2 1 ATOM 5849 N N . LEU E 2 144 ? -48.893 -19.804 -29.221 1.00 40.93 ? 351 LEU E N 1 ATOM 5850 C CA . LEU E 2 144 ? -47.872 -19.004 -29.888 1.00 47.62 ? 351 LEU E CA 1 ATOM 5851 C C . LEU E 2 144 ? -46.740 -19.897 -30.371 1.00 53.26 ? 351 LEU E C 1 ATOM 5852 O O . LEU E 2 144 ? -46.041 -20.502 -29.548 1.00 54.36 ? 351 LEU E O 1 ATOM 5853 C CB . LEU E 2 144 ? -47.333 -17.906 -28.958 1.00 38.50 ? 351 LEU E CB 1 ATOM 5854 C CG . LEU E 2 144 ? -48.316 -16.917 -28.318 1.00 37.92 ? 351 LEU E CG 1 ATOM 5855 C CD1 . LEU E 2 144 ? -47.652 -16.162 -27.170 1.00 36.24 ? 351 LEU E CD1 1 ATOM 5856 C CD2 . LEU E 2 144 ? -48.903 -15.943 -29.327 1.00 31.05 ? 351 LEU E CD2 1 ATOM 5857 N N . PRO E 2 145 ? -46.574 -20.000 -31.708 1.00 49.81 ? 352 PRO E N 1 ATOM 5858 C CA . PRO E 2 145 ? -45.552 -20.855 -32.322 1.00 53.90 ? 352 PRO E CA 1 ATOM 5859 C C . PRO E 2 145 ? -44.138 -20.447 -31.908 1.00 63.75 ? 352 PRO E C 1 ATOM 5860 O O . PRO E 2 145 ? -43.916 -19.280 -31.565 1.00 69.52 ? 352 PRO E O 1 ATOM 5861 C CB . PRO E 2 145 ? -45.758 -20.656 -33.834 1.00 43.75 ? 352 PRO E CB 1 ATOM 5862 C CG . PRO E 2 145 ? -46.676 -19.497 -33.983 1.00 47.44 ? 352 PRO E CG 1 ATOM 5863 C CD . PRO E 2 145 ? -47.460 -19.384 -32.714 1.00 53.15 ? 352 PRO E CD 1 ATOM 5864 N N . PRO E 2 146 ? -43.189 -21.405 -31.932 1.00 63.44 ? 353 PRO E N 1 ATOM 5865 C CA . PRO E 2 146 ? -41.817 -21.155 -31.484 1.00 64.29 ? 353 PRO E CA 1 ATOM 5866 C C . PRO E 2 146 ? -41.067 -20.213 -32.419 1.00 71.47 ? 353 PRO E C 1 ATOM 5867 O O . PRO E 2 146 ? -41.285 -20.247 -33.637 1.00 70.11 ? 353 PRO E O 1 ATOM 5868 C CB . PRO E 2 146 ? -41.183 -22.548 -31.500 1.00 60.79 ? 353 PRO E CB 1 ATOM 5869 C CG . PRO E 2 146 ? -41.961 -23.302 -32.523 1.00 57.06 ? 353 PRO E CG 1 ATOM 5870 C CD . PRO E 2 146 ? -43.362 -22.780 -32.441 1.00 53.69 ? 353 PRO E CD 1 ATOM 5871 N N . SER E 2 147 ? -40.208 -19.375 -31.841 1.00 69.20 ? 354 SER E N 1 ATOM 5872 C CA . SER E 2 147 ? -39.381 -18.429 -32.605 1.00 78.72 ? 354 SER E CA 1 ATOM 5873 C C . SER E 2 147 ? -38.482 -19.120 -33.637 1.00 80.64 ? 354 SER E C 1 ATOM 5874 O O . SER E 2 147 ? -37.999 -20.234 -33.404 1.00 77.82 ? 354 SER E O 1 ATOM 5875 C CB . SER E 2 147 ? -38.528 -17.582 -31.652 1.00 72.39 ? 354 SER E CB 1 ATOM 5876 O OG . SER E 2 147 ? -37.428 -16.982 -32.322 1.00 65.33 ? 354 SER E OG 1 ATOM 5877 N N . ARG E 2 148 ? -38.267 -18.444 -34.769 1.00 76.47 ? 355 ARG E N 1 ATOM 5878 C CA . ARG E 2 148 ? -37.339 -18.904 -35.810 1.00 76.04 ? 355 ARG E CA 1 ATOM 5879 C C . ARG E 2 148 ? -35.921 -19.061 -35.249 1.00 69.18 ? 355 ARG E C 1 ATOM 5880 O O . ARG E 2 148 ? -35.211 -20.016 -35.589 1.00 54.38 ? 355 ARG E O 1 ATOM 5881 C CB . ARG E 2 148 ? -37.343 -17.944 -37.009 1.00 61.13 ? 355 ARG E CB 1 ATOM 5882 N N . GLU E 2 149 ? -35.541 -18.135 -34.368 1.00 66.15 ? 356 GLU E N 1 ATOM 5883 C CA . GLU E 2 149 ? -34.228 -18.136 -33.724 1.00 68.99 ? 356 GLU E CA 1 ATOM 5884 C C . GLU E 2 149 ? -34.061 -19.251 -32.679 1.00 69.51 ? 356 GLU E C 1 ATOM 5885 O O . GLU E 2 149 ? -33.023 -19.331 -32.012 1.00 64.85 ? 356 GLU E O 1 ATOM 5886 C CB . GLU E 2 149 ? -33.934 -16.759 -33.109 1.00 63.97 ? 356 GLU E CB 1 ATOM 5887 N N . GLU E 2 150 ? -35.080 -20.103 -32.545 1.00 70.24 ? 357 GLU E N 1 ATOM 5888 C CA . GLU E 2 150 ? -35.027 -21.278 -31.662 1.00 76.68 ? 357 GLU E CA 1 ATOM 5889 C C . GLU E 2 150 ? -34.997 -22.599 -32.446 1.00 71.85 ? 357 GLU E C 1 ATOM 5890 O O . GLU E 2 150 ? -34.820 -23.667 -31.859 1.00 79.15 ? 357 GLU E O 1 ATOM 5891 C CB . GLU E 2 150 ? -36.209 -21.273 -30.674 1.00 79.32 ? 357 GLU E CB 1 ATOM 5892 C CG . GLU E 2 150 ? -36.079 -22.258 -29.510 1.00 74.75 ? 357 GLU E CG 1 ATOM 5893 C CD . GLU E 2 150 ? -37.292 -22.280 -28.591 1.00 74.57 ? 357 GLU E CD 1 ATOM 5894 O OE1 . GLU E 2 150 ? -38.434 -22.123 -29.082 1.00 69.30 ? 357 GLU E OE1 1 ATOM 5895 O OE2 . GLU E 2 150 ? -37.101 -22.468 -27.368 1.00 68.22 ? 357 GLU E OE2 1 ATOM 5896 N N . MET E 2 151 ? -35.160 -22.520 -33.766 1.00 74.39 ? 358 MET E N 1 ATOM 5897 C CA . MET E 2 151 ? -35.260 -23.712 -34.619 1.00 78.79 ? 358 MET E CA 1 ATOM 5898 C C . MET E 2 151 ? -33.969 -24.514 -34.742 1.00 84.99 ? 358 MET E C 1 ATOM 5899 O O . MET E 2 151 ? -34.000 -25.732 -34.961 1.00 81.31 ? 358 MET E O 1 ATOM 5900 C CB . MET E 2 151 ? -35.785 -23.344 -36.004 1.00 75.67 ? 358 MET E CB 1 ATOM 5901 C CG . MET E 2 151 ? -37.279 -23.088 -36.021 1.00 82.04 ? 358 MET E CG 1 ATOM 5902 S SD . MET E 2 151 ? -38.179 -24.304 -35.037 1.00 79.14 ? 358 MET E SD 1 ATOM 5903 C CE . MET E 2 151 ? -39.844 -23.991 -35.609 1.00 73.98 ? 358 MET E CE 1 ATOM 5904 N N . THR E 2 152 ? -32.843 -23.820 -34.605 1.00 91.97 ? 359 THR E N 1 ATOM 5905 C CA . THR E 2 152 ? -31.531 -24.456 -34.585 1.00 93.44 ? 359 THR E CA 1 ATOM 5906 C C . THR E 2 152 ? -31.113 -24.740 -33.138 1.00 89.31 ? 359 THR E C 1 ATOM 5907 O O . THR E 2 152 ? -30.043 -24.322 -32.687 1.00 86.69 ? 359 THR E O 1 ATOM 5908 C CB . THR E 2 152 ? -30.475 -23.604 -35.321 1.00 95.05 ? 359 THR E CB 1 ATOM 5909 O OG1 . THR E 2 152 ? -30.530 -22.253 -34.844 1.00 84.71 ? 359 THR E OG1 1 ATOM 5910 C CG2 . THR E 2 152 ? -30.723 -23.622 -36.835 1.00 87.82 ? 359 THR E CG2 1 ATOM 5911 N N . LYS E 2 153 ? -31.988 -25.445 -32.419 1.00 86.59 ? 360 LYS E N 1 ATOM 5912 C CA . LYS E 2 153 ? -31.744 -25.878 -31.041 1.00 83.99 ? 360 LYS E CA 1 ATOM 5913 C C . LYS E 2 153 ? -32.197 -27.329 -30.851 1.00 84.48 ? 360 LYS E C 1 ATOM 5914 O O . LYS E 2 153 ? -32.959 -27.862 -31.667 1.00 72.23 ? 360 LYS E O 1 ATOM 5915 C CB . LYS E 2 153 ? -32.464 -24.963 -30.041 1.00 77.27 ? 360 LYS E CB 1 ATOM 5916 C CG . LYS E 2 153 ? -31.824 -23.593 -29.838 1.00 75.20 ? 360 LYS E CG 1 ATOM 5917 C CD . LYS E 2 153 ? -30.654 -23.629 -28.862 1.00 65.81 ? 360 LYS E CD 1 ATOM 5918 C CE . LYS E 2 153 ? -31.117 -23.858 -27.428 1.00 74.85 ? 360 LYS E CE 1 ATOM 5919 N NZ . LYS E 2 153 ? -30.006 -23.763 -26.434 1.00 65.99 ? 360 LYS E NZ 1 ATOM 5920 N N . ASN E 2 154 ? -31.724 -27.959 -29.775 1.00 89.37 ? 361 ASN E N 1 ATOM 5921 C CA . ASN E 2 154 ? -32.074 -29.347 -29.458 1.00 99.32 ? 361 ASN E CA 1 ATOM 5922 C C . ASN E 2 154 ? -33.575 -29.548 -29.229 1.00 105.62 ? 361 ASN E C 1 ATOM 5923 O O . ASN E 2 154 ? -34.137 -30.576 -29.615 1.00 103.43 ? 361 ASN E O 1 ATOM 5924 C CB . ASN E 2 154 ? -31.277 -29.846 -28.248 1.00 90.38 ? 361 ASN E CB 1 ATOM 5925 N N . GLN E 2 155 ? -34.212 -28.557 -28.605 1.00 101.26 ? 362 GLN E N 1 ATOM 5926 C CA . GLN E 2 155 ? -35.651 -28.583 -28.329 1.00 93.30 ? 362 GLN E CA 1 ATOM 5927 C C . GLN E 2 155 ? -36.295 -27.212 -28.557 1.00 94.37 ? 362 GLN E C 1 ATOM 5928 O O . GLN E 2 155 ? -35.629 -26.179 -28.436 1.00 102.99 ? 362 GLN E O 1 ATOM 5929 C CB . GLN E 2 155 ? -35.903 -29.040 -26.891 1.00 80.38 ? 362 GLN E CB 1 ATOM 5930 C CG . GLN E 2 155 ? -35.744 -30.533 -26.664 1.00 66.75 ? 362 GLN E CG 1 ATOM 5931 C CD . GLN E 2 155 ? -35.729 -30.904 -25.196 1.00 70.87 ? 362 GLN E CD 1 ATOM 5932 O OE1 . GLN E 2 155 ? -35.462 -30.069 -24.329 1.00 66.16 ? 362 GLN E OE1 1 ATOM 5933 N NE2 . GLN E 2 155 ? -36.008 -32.168 -24.908 1.00 69.65 ? 362 GLN E NE2 1 ATOM 5934 N N . VAL E 2 156 ? -37.586 -27.210 -28.888 1.00 87.09 ? 363 VAL E N 1 ATOM 5935 C CA . VAL E 2 156 ? -38.340 -25.961 -29.075 1.00 73.21 ? 363 VAL E CA 1 ATOM 5936 C C . VAL E 2 156 ? -39.479 -25.806 -28.062 1.00 71.72 ? 363 VAL E C 1 ATOM 5937 O O . VAL E 2 156 ? -40.051 -26.794 -27.593 1.00 63.87 ? 363 VAL E O 1 ATOM 5938 C CB . VAL E 2 156 ? -38.883 -25.795 -30.517 1.00 63.60 ? 363 VAL E CB 1 ATOM 5939 C CG1 . VAL E 2 156 ? -37.736 -25.702 -31.514 1.00 64.71 ? 363 VAL E CG1 1 ATOM 5940 C CG2 . VAL E 2 156 ? -39.838 -26.921 -30.887 1.00 50.85 ? 363 VAL E CG2 1 ATOM 5941 N N . SER E 2 157 ? -39.795 -24.555 -27.738 1.00 73.72 ? 364 SER E N 1 ATOM 5942 C CA . SER E 2 157 ? -40.833 -24.230 -26.766 1.00 62.11 ? 364 SER E CA 1 ATOM 5943 C C . SER E 2 157 ? -42.141 -23.912 -27.479 1.00 58.14 ? 364 SER E C 1 ATOM 5944 O O . SER E 2 157 ? -42.179 -23.048 -28.358 1.00 56.96 ? 364 SER E O 1 ATOM 5945 C CB . SER E 2 157 ? -40.412 -23.028 -25.910 1.00 62.35 ? 364 SER E CB 1 ATOM 5946 O OG . SER E 2 157 ? -39.026 -23.051 -25.611 1.00 65.54 ? 364 SER E OG 1 ATOM 5947 N N . LEU E 2 158 ? -43.203 -24.627 -27.112 1.00 54.07 ? 365 LEU E N 1 ATOM 5948 C CA . LEU E 2 158 ? -44.557 -24.285 -27.547 1.00 50.17 ? 365 LEU E CA 1 ATOM 5949 C C . LEU E 2 158 ? -45.257 -23.527 -26.426 1.00 50.10 ? 365 LEU E C 1 ATOM 5950 O O . LEU E 2 158 ? -45.291 -23.985 -25.274 1.00 43.12 ? 365 LEU E O 1 ATOM 5951 C CB . LEU E 2 158 ? -45.362 -25.530 -27.926 1.00 51.19 ? 365 LEU E CB 1 ATOM 5952 C CG . LEU E 2 158 ? -44.825 -26.512 -28.968 1.00 50.20 ? 365 LEU E CG 1 ATOM 5953 C CD1 . LEU E 2 158 ? -45.966 -27.409 -29.412 1.00 49.07 ? 365 LEU E CD1 1 ATOM 5954 C CD2 . LEU E 2 158 ? -44.205 -25.805 -30.165 1.00 50.32 ? 365 LEU E CD2 1 ATOM 5955 N N . VAL E 2 159 ? -45.818 -22.372 -26.776 1.00 48.77 ? 366 VAL E N 1 ATOM 5956 C CA . VAL E 2 159 ? -46.285 -21.406 -25.784 1.00 42.65 ? 366 VAL E CA 1 ATOM 5957 C C . VAL E 2 159 ? -47.805 -21.234 -25.791 1.00 45.17 ? 366 VAL E C 1 ATOM 5958 O O . VAL E 2 159 ? -48.432 -21.052 -26.843 1.00 40.87 ? 366 VAL E O 1 ATOM 5959 C CB . VAL E 2 159 ? -45.586 -20.040 -25.967 1.00 40.81 ? 366 VAL E CB 1 ATOM 5960 C CG1 . VAL E 2 159 ? -45.942 -19.083 -24.839 1.00 37.31 ? 366 VAL E CG1 1 ATOM 5961 C CG2 . VAL E 2 159 ? -44.076 -20.222 -26.028 1.00 35.35 ? 366 VAL E CG2 1 ATOM 5962 N N . CYS E 2 160 ? -48.387 -21.312 -24.600 1.00 38.74 ? 367 CYS E N 1 ATOM 5963 C CA . CYS E 2 160 ? -49.795 -21.020 -24.420 1.00 37.20 ? 367 CYS E CA 1 ATOM 5964 C C . CYS E 2 160 ? -49.963 -19.819 -23.498 1.00 32.26 ? 367 CYS E C 1 ATOM 5965 O O . CYS E 2 160 ? -49.686 -19.911 -22.293 1.00 39.14 ? 367 CYS E O 1 ATOM 5966 C CB . CYS E 2 160 ? -50.502 -22.246 -23.838 1.00 40.64 ? 367 CYS E CB 1 ATOM 5967 S SG . CYS E 2 160 ? -52.301 -22.259 -23.972 1.00 58.92 ? 367 CYS E SG 1 ATOM 5968 N N . LEU E 2 161 ? -50.407 -18.697 -24.065 1.00 32.74 ? 368 LEU E N 1 ATOM 5969 C CA . LEU E 2 161 ? -50.789 -17.512 -23.288 1.00 28.50 ? 368 LEU E CA 1 ATOM 5970 C C . LEU E 2 161 ? -52.270 -17.551 -22.917 1.00 30.96 ? 368 LEU E C 1 ATOM 5971 O O . LEU E 2 161 ? -53.142 -17.617 -23.788 1.00 33.33 ? 368 LEU E O 1 ATOM 5972 C CB . LEU E 2 161 ? -50.447 -16.207 -24.045 1.00 28.01 ? 368 LEU E CB 1 ATOM 5973 C CG . LEU E 2 161 ? -51.085 -14.860 -23.644 1.00 27.80 ? 368 LEU E CG 1 ATOM 5974 C CD1 . LEU E 2 161 ? -50.767 -14.439 -22.204 1.00 25.62 ? 368 LEU E CD1 1 ATOM 5975 C CD2 . LEU E 2 161 ? -50.668 -13.757 -24.604 1.00 27.99 ? 368 LEU E CD2 1 ATOM 5976 N N . VAL E 2 162 ? -52.541 -17.507 -21.615 1.00 26.85 ? 369 VAL E N 1 ATOM 5977 C CA . VAL E 2 162 ? -53.902 -17.446 -21.092 1.00 26.81 ? 369 VAL E CA 1 ATOM 5978 C C . VAL E 2 162 ? -54.044 -16.116 -20.358 1.00 28.76 ? 369 VAL E C 1 ATOM 5979 O O . VAL E 2 162 ? -53.385 -15.905 -19.338 1.00 34.26 ? 369 VAL E O 1 ATOM 5980 C CB . VAL E 2 162 ? -54.198 -18.603 -20.109 1.00 27.59 ? 369 VAL E CB 1 ATOM 5981 C CG1 . VAL E 2 162 ? -55.679 -18.652 -19.761 1.00 27.36 ? 369 VAL E CG1 1 ATOM 5982 C CG2 . VAL E 2 162 ? -53.738 -19.944 -20.675 1.00 31.78 ? 369 VAL E CG2 1 ATOM 5983 N N . LYS E 2 163 ? -54.891 -15.223 -20.862 1.00 28.39 ? 370 LYS E N 1 ATOM 5984 C CA . LYS E 2 163 ? -54.992 -13.873 -20.281 1.00 36.80 ? 370 LYS E CA 1 ATOM 5985 C C . LYS E 2 163 ? -56.429 -13.361 -20.071 1.00 38.65 ? 370 LYS E C 1 ATOM 5986 O O . LYS E 2 163 ? -57.389 -13.909 -20.619 1.00 38.15 ? 370 LYS E O 1 ATOM 5987 C CB . LYS E 2 163 ? -54.140 -12.869 -21.074 1.00 28.77 ? 370 LYS E CB 1 ATOM 5988 C CG . LYS E 2 163 ? -54.769 -12.334 -22.354 1.00 37.28 ? 370 LYS E CG 1 ATOM 5989 C CD . LYS E 2 163 ? -53.930 -11.191 -22.927 1.00 37.63 ? 370 LYS E CD 1 ATOM 5990 C CE . LYS E 2 163 ? -54.794 -10.079 -23.508 1.00 42.59 ? 370 LYS E CE 1 ATOM 5991 N NZ . LYS E 2 163 ? -55.210 -9.051 -22.508 1.00 50.79 ? 370 LYS E NZ 1 ATOM 5992 N N . GLY E 2 164 ? -56.560 -12.329 -19.242 1.00 37.23 ? 371 GLY E N 1 ATOM 5993 C CA . GLY E 2 164 ? -57.849 -11.673 -18.990 1.00 36.95 ? 371 GLY E CA 1 ATOM 5994 C C . GLY E 2 164 ? -58.835 -12.460 -18.133 1.00 38.82 ? 371 GLY E C 1 ATOM 5995 O O . GLY E 2 164 ? -60.035 -12.170 -18.125 1.00 36.78 ? 371 GLY E O 1 ATOM 5996 N N . PHE E 2 165 ? -58.340 -13.459 -17.413 1.00 33.75 ? 372 PHE E N 1 ATOM 5997 C CA . PHE E 2 165 ? -59.224 -14.304 -16.627 1.00 31.30 ? 372 PHE E CA 1 ATOM 5998 C C . PHE E 2 165 ? -59.308 -13.853 -15.177 1.00 32.40 ? 372 PHE E C 1 ATOM 5999 O O . PHE E 2 165 ? -58.329 -13.362 -14.614 1.00 29.80 ? 372 PHE E O 1 ATOM 6000 C CB . PHE E 2 165 ? -58.866 -15.799 -16.741 1.00 27.57 ? 372 PHE E CB 1 ATOM 6001 C CG . PHE E 2 165 ? -57.508 -16.171 -16.196 1.00 30.11 ? 372 PHE E CG 1 ATOM 6002 C CD1 . PHE E 2 165 ? -56.388 -16.185 -17.023 1.00 29.79 ? 372 PHE E CD1 1 ATOM 6003 C CD2 . PHE E 2 165 ? -57.358 -16.569 -14.871 1.00 27.59 ? 372 PHE E CD2 1 ATOM 6004 C CE1 . PHE E 2 165 ? -55.140 -16.557 -16.526 1.00 32.54 ? 372 PHE E CE1 1 ATOM 6005 C CE2 . PHE E 2 165 ? -56.117 -16.938 -14.371 1.00 32.17 ? 372 PHE E CE2 1 ATOM 6006 C CZ . PHE E 2 165 ? -55.004 -16.932 -15.200 1.00 33.87 ? 372 PHE E CZ 1 ATOM 6007 N N . TYR E 2 166 ? -60.513 -13.978 -14.625 1.00 32.07 ? 373 TYR E N 1 ATOM 6008 C CA . TYR E 2 166 ? -60.793 -13.790 -13.210 1.00 30.33 ? 373 TYR E CA 1 ATOM 6009 C C . TYR E 2 166 ? -61.888 -14.806 -12.845 1.00 32.73 ? 373 TYR E C 1 ATOM 6010 O O . TYR E 2 166 ? -62.734 -15.132 -13.685 1.00 33.22 ? 373 TYR E O 1 ATOM 6011 C CB . TYR E 2 166 ? -61.240 -12.341 -12.874 1.00 30.94 ? 373 TYR E CB 1 ATOM 6012 C CG . TYR E 2 166 ? -61.213 -12.066 -11.360 1.00 26.40 ? 373 TYR E CG 1 ATOM 6013 C CD1 . TYR E 2 166 ? -62.363 -12.207 -10.585 1.00 28.30 ? 373 TYR E CD1 1 ATOM 6014 C CD2 . TYR E 2 166 ? -60.025 -11.726 -10.709 1.00 28.00 ? 373 TYR E CD2 1 ATOM 6015 C CE1 . TYR E 2 166 ? -62.336 -12.005 -9.204 1.00 29.53 ? 373 TYR E CE1 1 ATOM 6016 C CE2 . TYR E 2 166 ? -59.987 -11.509 -9.326 1.00 28.32 ? 373 TYR E CE2 1 ATOM 6017 C CZ . TYR E 2 166 ? -61.150 -11.653 -8.583 1.00 29.41 ? 373 TYR E CZ 1 ATOM 6018 O OH . TYR E 2 166 ? -61.133 -11.455 -7.219 1.00 30.04 ? 373 TYR E OH 1 ATOM 6019 N N . PRO E 2 167 ? -61.847 -15.356 -11.617 1.00 31.63 ? 374 PRO E N 1 ATOM 6020 C CA . PRO E 2 167 ? -60.725 -15.253 -10.679 1.00 36.40 ? 374 PRO E CA 1 ATOM 6021 C C . PRO E 2 167 ? -59.526 -16.090 -11.152 1.00 35.25 ? 374 PRO E C 1 ATOM 6022 O O . PRO E 2 167 ? -59.567 -16.651 -12.257 1.00 32.67 ? 374 PRO E O 1 ATOM 6023 C CB . PRO E 2 167 ? -61.313 -15.754 -9.355 1.00 33.18 ? 374 PRO E CB 1 ATOM 6024 C CG . PRO E 2 167 ? -62.496 -16.573 -9.731 1.00 34.63 ? 374 PRO E CG 1 ATOM 6025 C CD . PRO E 2 167 ? -63.024 -16.011 -11.020 1.00 34.55 ? 374 PRO E CD 1 ATOM 6026 N N . SER E 2 168 ? -58.474 -16.161 -10.342 1.00 32.07 ? 375 SER E N 1 ATOM 6027 C CA . SER E 2 168 ? -57.220 -16.800 -10.764 1.00 32.09 ? 375 SER E CA 1 ATOM 6028 C C . SER E 2 168 ? -57.256 -18.323 -10.690 1.00 32.73 ? 375 SER E C 1 ATOM 6029 O O . SER E 2 168 ? -56.303 -18.981 -11.085 1.00 33.14 ? 375 SER E O 1 ATOM 6030 C CB . SER E 2 168 ? -56.056 -16.288 -9.923 1.00 35.04 ? 375 SER E CB 1 ATOM 6031 O OG . SER E 2 168 ? -56.238 -16.624 -8.557 1.00 42.31 ? 375 SER E OG 1 ATOM 6032 N N . ASP E 2 169 ? -58.349 -18.875 -10.169 1.00 37.71 ? 376 ASP E N 1 ATOM 6033 C CA . ASP E 2 169 ? -58.501 -20.317 -10.028 1.00 41.08 ? 376 ASP E CA 1 ATOM 6034 C C . ASP E 2 169 ? -58.542 -20.942 -11.408 1.00 40.23 ? 376 ASP E C 1 ATOM 6035 O O . ASP E 2 169 ? -59.439 -20.668 -12.206 1.00 38.77 ? 376 ASP E O 1 ATOM 6036 C CB . ASP E 2 169 ? -59.758 -20.646 -9.224 1.00 50.69 ? 376 ASP E CB 1 ATOM 6037 C CG . ASP E 2 169 ? -59.719 -20.058 -7.820 1.00 62.16 ? 376 ASP E CG 1 ATOM 6038 O OD1 . ASP E 2 169 ? -60.741 -19.479 -7.387 1.00 69.55 ? 376 ASP E OD1 1 ATOM 6039 O OD2 . ASP E 2 169 ? -58.662 -20.160 -7.156 1.00 57.82 ? 376 ASP E OD2 1 ATOM 6040 N N . ILE E 2 170 ? -57.538 -21.757 -11.699 1.00 40.09 ? 377 ILE E N 1 ATOM 6041 C CA . ILE E 2 170 ? -57.337 -22.227 -13.058 1.00 40.12 ? 377 ILE E CA 1 ATOM 6042 C C . ILE E 2 170 ? -56.597 -23.564 -13.115 1.00 40.19 ? 377 ILE E C 1 ATOM 6043 O O . ILE E 2 170 ? -56.037 -24.032 -12.115 1.00 39.51 ? 377 ILE E O 1 ATOM 6044 C CB . ILE E 2 170 ? -56.634 -21.133 -13.911 1.00 42.76 ? 377 ILE E CB 1 ATOM 6045 C CG1 . ILE E 2 170 ? -56.836 -21.382 -15.416 1.00 29.14 ? 377 ILE E CG1 1 ATOM 6046 C CG2 . ILE E 2 170 ? -55.174 -20.972 -13.503 1.00 40.04 ? 377 ILE E CG2 1 ATOM 6047 C CD1 . ILE E 2 170 ? -56.805 -20.119 -16.248 1.00 36.22 ? 377 ILE E CD1 1 ATOM 6048 N N . ALA E 2 171 ? -56.649 -24.192 -14.284 1.00 31.80 ? 378 ALA E N 1 ATOM 6049 C CA . ALA E 2 171 ? -55.890 -25.388 -14.564 1.00 34.13 ? 378 ALA E CA 1 ATOM 6050 C C . ALA E 2 171 ? -55.519 -25.338 -16.035 1.00 36.94 ? 378 ALA E C 1 ATOM 6051 O O . ALA E 2 171 ? -56.366 -25.054 -16.876 1.00 32.83 ? 378 ALA E O 1 ATOM 6052 C CB . ALA E 2 171 ? -56.709 -26.631 -14.248 1.00 40.33 ? 378 ALA E CB 1 ATOM 6053 N N . VAL E 2 172 ? -54.238 -25.559 -16.325 1.00 41.03 ? 379 VAL E N 1 ATOM 6054 C CA . VAL E 2 172 ? -53.729 -25.553 -17.688 1.00 40.76 ? 379 VAL E CA 1 ATOM 6055 C C . VAL E 2 172 ? -52.986 -26.864 -17.895 1.00 46.36 ? 379 VAL E C 1 ATOM 6056 O O . VAL E 2 172 ? -52.087 -27.201 -17.124 1.00 42.45 ? 379 VAL E O 1 ATOM 6057 C CB . VAL E 2 172 ? -52.778 -24.356 -17.963 1.00 42.92 ? 379 VAL E CB 1 ATOM 6058 C CG1 . VAL E 2 172 ? -52.287 -24.377 -19.404 1.00 40.00 ? 379 VAL E CG1 1 ATOM 6059 C CG2 . VAL E 2 172 ? -53.466 -23.027 -17.673 1.00 42.46 ? 379 VAL E CG2 1 ATOM 6060 N N . GLU E 2 173 ? -53.377 -27.603 -18.931 1.00 43.56 ? 380 GLU E N 1 ATOM 6061 C CA . GLU E 2 173 ? -52.734 -28.870 -19.264 1.00 51.17 ? 380 GLU E CA 1 ATOM 6062 C C . GLU E 2 173 ? -52.440 -28.971 -20.753 1.00 51.88 ? 380 GLU E C 1 ATOM 6063 O O . GLU E 2 173 ? -53.038 -28.265 -21.570 1.00 41.15 ? 380 GLU E O 1 ATOM 6064 C CB . GLU E 2 173 ? -53.592 -30.055 -18.806 1.00 58.03 ? 380 GLU E CB 1 ATOM 6065 C CG . GLU E 2 173 ? -53.390 -30.415 -17.341 1.00 63.95 ? 380 GLU E CG 1 ATOM 6066 C CD . GLU E 2 173 ? -54.658 -30.880 -16.648 1.00 64.05 ? 380 GLU E CD 1 ATOM 6067 O OE1 . GLU E 2 173 ? -55.506 -31.548 -17.287 1.00 73.61 ? 380 GLU E OE1 1 ATOM 6068 O OE2 . GLU E 2 173 ? -54.800 -30.576 -15.446 1.00 60.82 ? 380 GLU E OE2 1 ATOM 6069 N N . TRP E 2 174 ? -51.512 -29.862 -21.087 1.00 56.47 ? 381 TRP E N 1 ATOM 6070 C CA . TRP E 2 174 ? -51.051 -30.046 -22.453 1.00 63.87 ? 381 TRP E CA 1 ATOM 6071 C C . TRP E 2 174 ? -51.217 -31.473 -22.863 1.00 60.29 ? 381 TRP E C 1 ATOM 6072 O O . TRP E 2 174 ? -51.080 -32.381 -22.040 1.00 58.63 ? 381 TRP E O 1 ATOM 6073 C CB . TRP E 2 174 ? -49.579 -29.687 -22.554 1.00 59.77 ? 381 TRP E CB 1 ATOM 6074 C CG . TRP E 2 174 ? -49.260 -28.220 -22.698 1.00 45.39 ? 381 TRP E CG 1 ATOM 6075 C CD1 . TRP E 2 174 ? -48.886 -27.331 -21.695 1.00 49.86 ? 381 TRP E CD1 1 ATOM 6076 C CD2 . TRP E 2 174 ? -49.222 -27.432 -23.942 1.00 41.89 ? 381 TRP E CD2 1 ATOM 6077 N NE1 . TRP E 2 174 ? -48.637 -26.084 -22.214 1.00 44.61 ? 381 TRP E NE1 1 ATOM 6078 C CE2 . TRP E 2 174 ? -48.817 -26.079 -23.558 1.00 40.09 ? 381 TRP E CE2 1 ATOM 6079 C CE3 . TRP E 2 174 ? -49.472 -27.705 -25.284 1.00 41.59 ? 381 TRP E CE3 1 ATOM 6080 C CZ2 . TRP E 2 174 ? -48.679 -25.059 -24.492 1.00 36.36 ? 381 TRP E CZ2 1 ATOM 6081 C CZ3 . TRP E 2 174 ? -49.336 -26.667 -26.214 1.00 39.28 ? 381 TRP E CZ3 1 ATOM 6082 C CH2 . TRP E 2 174 ? -48.948 -25.378 -25.826 1.00 38.11 ? 381 TRP E CH2 1 ATOM 6083 N N . GLU E 2 175 ? -51.490 -31.684 -24.147 1.00 58.86 ? 382 GLU E N 1 ATOM 6084 C CA . GLU E 2 175 ? -51.705 -33.026 -24.681 1.00 63.72 ? 382 GLU E CA 1 ATOM 6085 C C . GLU E 2 175 ? -51.508 -33.113 -26.199 1.00 67.81 ? 382 GLU E C 1 ATOM 6086 O O . GLU E 2 175 ? -51.664 -32.119 -26.913 1.00 69.79 ? 382 GLU E O 1 ATOM 6087 C CB . GLU E 2 175 ? -53.106 -33.510 -24.315 1.00 63.85 ? 382 GLU E CB 1 ATOM 6088 C CG . GLU E 2 175 ? -54.178 -32.457 -24.524 1.00 65.40 ? 382 GLU E CG 1 ATOM 6089 C CD . GLU E 2 175 ? -55.460 -33.042 -25.060 1.00 62.83 ? 382 GLU E CD 1 ATOM 6090 O OE1 . GLU E 2 175 ? -55.888 -32.614 -26.154 1.00 70.24 ? 382 GLU E OE1 1 ATOM 6091 O OE2 . GLU E 2 175 ? -56.025 -33.934 -24.397 1.00 62.57 ? 382 GLU E OE2 1 ATOM 6092 N N . SER E 2 176 ? -51.168 -34.309 -26.679 1.00 73.45 ? 383 SER E N 1 ATOM 6093 C CA . SER E 2 176 ? -51.076 -34.581 -28.115 1.00 78.68 ? 383 SER E CA 1 ATOM 6094 C C . SER E 2 176 ? -51.768 -35.893 -28.468 1.00 82.85 ? 383 SER E C 1 ATOM 6095 O O . SER E 2 176 ? -51.543 -36.920 -27.816 1.00 76.28 ? 383 SER E O 1 ATOM 6096 C CB . SER E 2 176 ? -49.620 -34.620 -28.577 1.00 73.38 ? 383 SER E CB 1 ATOM 6097 O OG . SER E 2 176 ? -49.547 -34.601 -29.991 1.00 66.27 ? 383 SER E OG 1 ATOM 6098 N N . ASN E 2 177 ? -52.607 -35.841 -29.503 1.00 84.12 ? 384 ASN E N 1 ATOM 6099 C CA . ASN E 2 177 ? -53.398 -36.988 -29.964 1.00 85.74 ? 384 ASN E CA 1 ATOM 6100 C C . ASN E 2 177 ? -54.153 -37.698 -28.834 1.00 80.36 ? 384 ASN E C 1 ATOM 6101 O O . ASN E 2 177 ? -54.140 -38.926 -28.738 1.00 78.22 ? 384 ASN E O 1 ATOM 6102 C CB . ASN E 2 177 ? -52.520 -37.969 -30.753 1.00 83.51 ? 384 ASN E CB 1 ATOM 6103 N N . GLY E 2 178 ? -54.802 -36.909 -27.980 1.00 72.97 ? 385 GLY E N 1 ATOM 6104 C CA . GLY E 2 178 ? -55.559 -37.432 -26.843 1.00 73.99 ? 385 GLY E CA 1 ATOM 6105 C C . GLY E 2 178 ? -54.718 -38.131 -25.787 1.00 75.97 ? 385 GLY E C 1 ATOM 6106 O O . GLY E 2 178 ? -55.204 -39.034 -25.103 1.00 78.62 ? 385 GLY E O 1 ATOM 6107 N N . GLN E 2 179 ? -53.456 -37.723 -25.659 1.00 71.23 ? 386 GLN E N 1 ATOM 6108 C CA . GLN E 2 179 ? -52.546 -38.291 -24.659 1.00 71.95 ? 386 GLN E CA 1 ATOM 6109 C C . GLN E 2 179 ? -51.765 -37.171 -23.968 1.00 66.14 ? 386 GLN E C 1 ATOM 6110 O O . GLN E 2 179 ? -51.160 -36.339 -24.641 1.00 63.70 ? 386 GLN E O 1 ATOM 6111 C CB . GLN E 2 179 ? -51.564 -39.287 -25.298 1.00 84.44 ? 386 GLN E CB 1 ATOM 6112 C CG . GLN E 2 179 ? -52.153 -40.266 -26.314 1.00 81.48 ? 386 GLN E CG 1 ATOM 6113 C CD . GLN E 2 179 ? -53.018 -41.350 -25.692 1.00 84.23 ? 386 GLN E CD 1 ATOM 6114 O OE1 . GLN E 2 179 ? -52.792 -41.782 -24.557 1.00 76.26 ? 386 GLN E OE1 1 ATOM 6115 N NE2 . GLN E 2 179 ? -54.013 -41.804 -26.443 1.00 84.61 ? 386 GLN E NE2 1 ATOM 6116 N N . PRO E 2 180 ? -51.762 -37.153 -22.622 1.00 64.03 ? 387 PRO E N 1 ATOM 6117 C CA . PRO E 2 180 ? -51.095 -36.073 -21.885 1.00 63.41 ? 387 PRO E CA 1 ATOM 6118 C C . PRO E 2 180 ? -49.595 -35.945 -22.178 1.00 68.17 ? 387 PRO E C 1 ATOM 6119 O O . PRO E 2 180 ? -48.866 -36.940 -22.146 1.00 69.54 ? 387 PRO E O 1 ATOM 6120 C CB . PRO E 2 180 ? -51.329 -36.446 -20.410 1.00 61.74 ? 387 PRO E CB 1 ATOM 6121 C CG . PRO E 2 180 ? -51.677 -37.898 -20.419 1.00 66.97 ? 387 PRO E CG 1 ATOM 6122 C CD . PRO E 2 180 ? -52.400 -38.123 -21.713 1.00 66.70 ? 387 PRO E CD 1 ATOM 6123 N N . GLU E 2 181 ? -49.160 -34.721 -22.481 1.00 65.89 ? 388 GLU E N 1 ATOM 6124 C CA . GLU E 2 181 ? -47.739 -34.385 -22.603 1.00 59.31 ? 388 GLU E CA 1 ATOM 6125 C C . GLU E 2 181 ? -47.303 -33.795 -21.270 1.00 53.01 ? 388 GLU E C 1 ATOM 6126 O O . GLU E 2 181 ? -47.895 -32.828 -20.802 1.00 55.06 ? 388 GLU E O 1 ATOM 6127 C CB . GLU E 2 181 ? -47.520 -33.365 -23.720 1.00 59.42 ? 388 GLU E CB 1 ATOM 6128 C CG . GLU E 2 181 ? -48.054 -33.791 -25.079 1.00 68.52 ? 388 GLU E CG 1 ATOM 6129 C CD . GLU E 2 181 ? -47.115 -34.733 -25.801 1.00 77.68 ? 388 GLU E CD 1 ATOM 6130 O OE1 . GLU E 2 181 ? -45.988 -34.308 -26.132 1.00 79.78 ? 388 GLU E OE1 1 ATOM 6131 O OE2 . GLU E 2 181 ? -47.507 -35.894 -26.041 1.00 86.77 ? 388 GLU E OE2 1 ATOM 6132 N N . ASN E 2 182 ? -46.291 -34.382 -20.643 1.00 50.92 ? 389 ASN E N 1 ATOM 6133 C CA . ASN E 2 182 ? -45.952 -34.000 -19.272 1.00 60.82 ? 389 ASN E CA 1 ATOM 6134 C C . ASN E 2 182 ? -44.714 -33.118 -19.146 1.00 57.55 ? 389 ASN E C 1 ATOM 6135 O O . ASN E 2 182 ? -44.324 -32.751 -18.029 1.00 57.92 ? 389 ASN E O 1 ATOM 6136 C CB . ASN E 2 182 ? -45.817 -35.240 -18.371 1.00 61.71 ? 389 ASN E CB 1 ATOM 6137 C CG . ASN E 2 182 ? -47.153 -35.748 -17.847 1.00 63.39 ? 389 ASN E CG 1 ATOM 6138 O OD1 . ASN E 2 182 ? -48.210 -35.471 -18.409 1.00 69.44 ? 389 ASN E OD1 1 ATOM 6139 N ND2 . ASN E 2 182 ? -47.102 -36.510 -16.759 1.00 70.76 ? 389 ASN E ND2 1 ATOM 6140 N N . ASN E 2 183 ? -44.103 -32.769 -20.277 1.00 47.84 ? 390 ASN E N 1 ATOM 6141 C CA . ASN E 2 183 ? -42.881 -31.963 -20.250 1.00 56.79 ? 390 ASN E CA 1 ATOM 6142 C C . ASN E 2 183 ? -43.144 -30.455 -20.375 1.00 59.83 ? 390 ASN E C 1 ATOM 6143 O O . ASN E 2 183 ? -42.489 -29.750 -21.149 1.00 65.58 ? 390 ASN E O 1 ATOM 6144 C CB . ASN E 2 183 ? -41.861 -32.456 -21.289 1.00 59.23 ? 390 ASN E CB 1 ATOM 6145 C CG . ASN E 2 183 ? -40.446 -31.978 -20.987 1.00 64.64 ? 390 ASN E CG 1 ATOM 6146 O OD1 . ASN E 2 183 ? -39.977 -32.060 -19.847 1.00 64.79 ? 390 ASN E OD1 1 ATOM 6147 N ND2 . ASN E 2 183 ? -39.762 -31.465 -22.010 1.00 53.08 ? 390 ASN E ND2 1 ATOM 6148 N N . TYR E 2 184 ? -44.108 -29.968 -19.600 1.00 55.32 ? 391 TYR E N 1 ATOM 6149 C CA . TYR E 2 184 ? -44.432 -28.553 -19.593 1.00 50.79 ? 391 TYR E CA 1 ATOM 6150 C C . TYR E 2 184 ? -44.243 -27.945 -18.217 1.00 49.88 ? 391 TYR E C 1 ATOM 6151 O O . TYR E 2 184 ? -44.289 -28.642 -17.200 1.00 49.81 ? 391 TYR E O 1 ATOM 6152 C CB . TYR E 2 184 ? -45.864 -28.296 -20.108 1.00 50.48 ? 391 TYR E CB 1 ATOM 6153 C CG . TYR E 2 184 ? -46.988 -28.803 -19.218 1.00 53.01 ? 391 TYR E CG 1 ATOM 6154 C CD1 . TYR E 2 184 ? -47.400 -28.085 -18.084 1.00 48.59 ? 391 TYR E CD1 1 ATOM 6155 C CD2 . TYR E 2 184 ? -47.655 -29.989 -19.519 1.00 49.05 ? 391 TYR E CD2 1 ATOM 6156 C CE1 . TYR E 2 184 ? -48.430 -28.547 -17.272 1.00 45.97 ? 391 TYR E CE1 1 ATOM 6157 C CE2 . TYR E 2 184 ? -48.692 -30.455 -18.719 1.00 51.81 ? 391 TYR E CE2 1 ATOM 6158 C CZ . TYR E 2 184 ? -49.072 -29.735 -17.597 1.00 53.34 ? 391 TYR E CZ 1 ATOM 6159 O OH . TYR E 2 184 ? -50.096 -30.201 -16.807 1.00 56.97 ? 391 TYR E OH 1 ATOM 6160 N N . LYS E 2 185 ? -44.009 -26.639 -18.196 1.00 45.70 ? 392 LYS E N 1 ATOM 6161 C CA . LYS E 2 185 ? -44.166 -25.871 -16.974 1.00 44.40 ? 392 LYS E CA 1 ATOM 6162 C C . LYS E 2 185 ? -45.107 -24.699 -17.249 1.00 48.07 ? 392 LYS E C 1 ATOM 6163 O O . LYS E 2 185 ? -45.348 -24.335 -18.411 1.00 49.65 ? 392 LYS E O 1 ATOM 6164 C CB . LYS E 2 185 ? -42.815 -25.406 -16.420 1.00 41.28 ? 392 LYS E CB 1 ATOM 6165 C CG . LYS E 2 185 ? -41.858 -26.528 -16.042 1.00 37.34 ? 392 LYS E CG 1 ATOM 6166 C CD . LYS E 2 185 ? -42.061 -27.002 -14.612 1.00 35.05 ? 392 LYS E CD 1 ATOM 6167 C CE . LYS E 2 185 ? -41.260 -28.269 -14.350 1.00 42.63 ? 392 LYS E CE 1 ATOM 6168 N NZ . LYS E 2 185 ? -41.368 -28.713 -12.930 1.00 47.04 ? 392 LYS E NZ 1 ATOM 6169 N N . THR E 2 186 ? -45.646 -24.136 -16.172 1.00 36.63 ? 393 THR E N 1 ATOM 6170 C CA . THR E 2 186 ? -46.660 -23.092 -16.228 1.00 34.62 ? 393 THR E CA 1 ATOM 6171 C C . THR E 2 186 ? -46.339 -22.119 -15.106 1.00 40.93 ? 393 THR E C 1 ATOM 6172 O O . THR E 2 186 ? -46.097 -22.547 -13.969 1.00 32.11 ? 393 THR E O 1 ATOM 6173 C CB . THR E 2 186 ? -48.072 -23.667 -15.956 1.00 36.19 ? 393 THR E CB 1 ATOM 6174 O OG1 . THR E 2 186 ? -48.378 -24.703 -16.899 1.00 39.96 ? 393 THR E OG1 1 ATOM 6175 C CG2 . THR E 2 186 ? -49.145 -22.577 -16.047 1.00 36.00 ? 393 THR E CG2 1 ATOM 6176 N N . THR E 2 187 ? -46.344 -20.825 -15.420 1.00 37.30 ? 394 THR E N 1 ATOM 6177 C CA . THR E 2 187 ? -46.130 -19.783 -14.418 1.00 37.40 ? 394 THR E CA 1 ATOM 6178 C C . THR E 2 187 ? -47.341 -19.727 -13.490 1.00 36.82 ? 394 THR E C 1 ATOM 6179 O O . THR E 2 187 ? -48.443 -20.063 -13.909 1.00 38.90 ? 394 THR E O 1 ATOM 6180 C CB . THR E 2 187 ? -45.924 -18.394 -15.070 1.00 39.20 ? 394 THR E CB 1 ATOM 6181 O OG1 . THR E 2 187 ? -47.131 -17.984 -15.728 1.00 41.20 ? 394 THR E OG1 1 ATOM 6182 C CG2 . THR E 2 187 ? -44.764 -18.419 -16.083 1.00 30.48 ? 394 THR E CG2 1 ATOM 6183 N N . PRO E 2 188 ? -47.143 -19.316 -12.224 1.00 37.41 ? 395 PRO E N 1 ATOM 6184 C CA . PRO E 2 188 ? -48.311 -18.970 -11.419 1.00 42.99 ? 395 PRO E CA 1 ATOM 6185 C C . PRO E 2 188 ? -49.076 -17.818 -12.093 1.00 42.63 ? 395 PRO E C 1 ATOM 6186 O O . PRO E 2 188 ? -48.531 -17.172 -12.984 1.00 39.49 ? 395 PRO E O 1 ATOM 6187 C CB . PRO E 2 188 ? -47.706 -18.511 -10.078 1.00 37.38 ? 395 PRO E CB 1 ATOM 6188 C CG . PRO E 2 188 ? -46.256 -18.296 -10.337 1.00 38.16 ? 395 PRO E CG 1 ATOM 6189 C CD . PRO E 2 188 ? -45.895 -19.236 -11.444 1.00 39.62 ? 395 PRO E CD 1 ATOM 6190 N N . PRO E 2 189 ? -50.336 -17.579 -11.693 1.00 39.79 ? 396 PRO E N 1 ATOM 6191 C CA . PRO E 2 189 ? -51.057 -16.466 -12.303 1.00 37.54 ? 396 PRO E CA 1 ATOM 6192 C C . PRO E 2 189 ? -50.467 -15.129 -11.876 1.00 34.35 ? 396 PRO E C 1 ATOM 6193 O O . PRO E 2 189 ? -50.034 -14.981 -10.730 1.00 29.82 ? 396 PRO E O 1 ATOM 6194 C CB . PRO E 2 189 ? -52.479 -16.631 -11.763 1.00 30.07 ? 396 PRO E CB 1 ATOM 6195 C CG . PRO E 2 189 ? -52.573 -18.068 -11.364 1.00 32.33 ? 396 PRO E CG 1 ATOM 6196 C CD . PRO E 2 189 ? -51.210 -18.369 -10.811 1.00 34.17 ? 396 PRO E CD 1 ATOM 6197 N N . VAL E 2 190 ? -50.434 -14.175 -12.800 1.00 29.63 ? 397 VAL E N 1 ATOM 6198 C CA . VAL E 2 190 ? -49.886 -12.849 -12.515 1.00 31.21 ? 397 VAL E CA 1 ATOM 6199 C C . VAL E 2 190 ? -51.010 -11.823 -12.577 1.00 31.32 ? 397 VAL E C 1 ATOM 6200 O O . VAL E 2 190 ? -51.836 -11.880 -13.484 1.00 32.78 ? 397 VAL E O 1 ATOM 6201 C CB . VAL E 2 190 ? -48.753 -12.482 -13.499 1.00 30.81 ? 397 VAL E CB 1 ATOM 6202 C CG1 . VAL E 2 190 ? -48.197 -11.092 -13.208 1.00 35.85 ? 397 VAL E CG1 1 ATOM 6203 C CG2 . VAL E 2 190 ? -47.639 -13.507 -13.415 1.00 27.25 ? 397 VAL E CG2 1 ATOM 6204 N N . LEU E 2 191 ? -51.054 -10.906 -11.609 1.00 28.71 ? 398 LEU E N 1 ATOM 6205 C CA . LEU E 2 191 ? -52.065 -9.846 -11.611 1.00 31.57 ? 398 LEU E CA 1 ATOM 6206 C C . LEU E 2 191 ? -51.710 -8.828 -12.687 1.00 34.08 ? 398 LEU E C 1 ATOM 6207 O O . LEU E 2 191 ? -50.585 -8.326 -12.730 1.00 31.02 ? 398 LEU E O 1 ATOM 6208 C CB . LEU E 2 191 ? -52.202 -9.159 -10.238 1.00 34.22 ? 398 LEU E CB 1 ATOM 6209 C CG . LEU E 2 191 ? -53.313 -8.096 -10.137 1.00 40.02 ? 398 LEU E CG 1 ATOM 6210 C CD1 . LEU E 2 191 ? -54.689 -8.671 -10.478 1.00 41.09 ? 398 LEU E CD1 1 ATOM 6211 C CD2 . LEU E 2 191 ? -53.351 -7.413 -8.774 1.00 33.64 ? 398 LEU E CD2 1 ATOM 6212 N N . ASP E 2 192 ? -52.664 -8.559 -13.571 1.00 30.63 ? 399 ASP E N 1 ATOM 6213 C CA . ASP E 2 192 ? -52.433 -7.657 -14.686 1.00 36.19 ? 399 ASP E CA 1 ATOM 6214 C C . ASP E 2 192 ? -52.981 -6.290 -14.289 1.00 38.37 ? 399 ASP E C 1 ATOM 6215 O O . ASP E 2 192 ? -53.650 -6.164 -13.258 1.00 43.09 ? 399 ASP E O 1 ATOM 6216 C CB . ASP E 2 192 ? -53.127 -8.204 -15.936 1.00 32.46 ? 399 ASP E CB 1 ATOM 6217 C CG . ASP E 2 192 ? -52.424 -7.828 -17.215 1.00 38.03 ? 399 ASP E CG 1 ATOM 6218 O OD1 . ASP E 2 192 ? -51.670 -6.830 -17.235 1.00 47.66 ? 399 ASP E OD1 1 ATOM 6219 O OD2 . ASP E 2 192 ? -52.634 -8.544 -18.218 1.00 36.46 ? 399 ASP E OD2 1 ATOM 6220 N N . SER E 2 193 ? -52.704 -5.265 -15.087 1.00 37.88 ? 400 SER E N 1 ATOM 6221 C CA . SER E 2 193 ? -53.135 -3.910 -14.735 1.00 37.53 ? 400 SER E CA 1 ATOM 6222 C C . SER E 2 193 ? -54.645 -3.648 -14.876 1.00 37.92 ? 400 SER E C 1 ATOM 6223 O O . SER E 2 193 ? -55.138 -2.668 -14.335 1.00 32.93 ? 400 SER E O 1 ATOM 6224 C CB . SER E 2 193 ? -52.336 -2.874 -15.523 1.00 38.01 ? 400 SER E CB 1 ATOM 6225 O OG . SER E 2 193 ? -52.435 -3.124 -16.909 1.00 39.05 ? 400 SER E OG 1 ATOM 6226 N N . ASP E 2 194 ? -55.375 -4.498 -15.603 1.00 35.77 ? 401 ASP E N 1 ATOM 6227 C CA . ASP E 2 194 ? -56.843 -4.355 -15.682 1.00 32.19 ? 401 ASP E CA 1 ATOM 6228 C C . ASP E 2 194 ? -57.580 -5.093 -14.551 1.00 30.89 ? 401 ASP E C 1 ATOM 6229 O O . ASP E 2 194 ? -58.806 -5.003 -14.425 1.00 29.44 ? 401 ASP E O 1 ATOM 6230 C CB . ASP E 2 194 ? -57.394 -4.763 -17.064 1.00 30.53 ? 401 ASP E CB 1 ATOM 6231 C CG . ASP E 2 194 ? -57.173 -6.228 -17.380 1.00 34.52 ? 401 ASP E CG 1 ATOM 6232 O OD1 . ASP E 2 194 ? -56.513 -6.927 -16.580 1.00 33.68 ? 401 ASP E OD1 1 ATOM 6233 O OD2 . ASP E 2 194 ? -57.661 -6.683 -18.442 1.00 34.81 ? 401 ASP E OD2 1 ATOM 6234 N N . GLY E 2 195 ? -56.826 -5.802 -13.718 1.00 33.60 ? 402 GLY E N 1 ATOM 6235 C CA . GLY E 2 195 ? -57.386 -6.433 -12.523 1.00 31.03 ? 402 GLY E CA 1 ATOM 6236 C C . GLY E 2 195 ? -57.699 -7.897 -12.753 1.00 33.09 ? 402 GLY E C 1 ATOM 6237 O O . GLY E 2 195 ? -58.211 -8.578 -11.858 1.00 24.94 ? 402 GLY E O 1 ATOM 6238 N N . SER E 2 196 ? -57.406 -8.375 -13.965 1.00 28.57 ? 403 SER E N 1 ATOM 6239 C CA . SER E 2 196 ? -57.528 -9.788 -14.287 1.00 26.79 ? 403 SER E CA 1 ATOM 6240 C C . SER E 2 196 ? -56.149 -10.443 -14.159 1.00 25.17 ? 403 SER E C 1 ATOM 6241 O O . SER E 2 196 ? -55.155 -9.758 -13.887 1.00 29.74 ? 403 SER E O 1 ATOM 6242 C CB . SER E 2 196 ? -58.106 -9.954 -15.704 1.00 31.42 ? 403 SER E CB 1 ATOM 6243 O OG . SER E 2 196 ? -57.207 -9.491 -16.691 1.00 27.84 ? 403 SER E OG 1 ATOM 6244 N N . PHE E 2 197 ? -56.084 -11.760 -14.331 1.00 26.59 ? 404 PHE E N 1 ATOM 6245 C CA . PHE E 2 197 ? -54.806 -12.469 -14.313 1.00 23.01 ? 404 PHE E CA 1 ATOM 6246 C C . PHE E 2 197 ? -54.398 -12.977 -15.692 1.00 28.12 ? 404 PHE E C 1 ATOM 6247 O O . PHE E 2 197 ? -55.231 -13.134 -16.573 1.00 20.26 ? 404 PHE E O 1 ATOM 6248 C CB . PHE E 2 197 ? -54.842 -13.643 -13.344 1.00 25.11 ? 404 PHE E CB 1 ATOM 6249 C CG . PHE E 2 197 ? -55.091 -13.245 -11.908 1.00 26.96 ? 404 PHE E CG 1 ATOM 6250 C CD1 . PHE E 2 197 ? -56.390 -13.066 -11.437 1.00 25.99 ? 404 PHE E CD1 1 ATOM 6251 C CD2 . PHE E 2 197 ? -54.033 -13.069 -11.029 1.00 26.18 ? 404 PHE E CD2 1 ATOM 6252 C CE1 . PHE E 2 197 ? -56.621 -12.716 -10.112 1.00 30.33 ? 404 PHE E CE1 1 ATOM 6253 C CE2 . PHE E 2 197 ? -54.256 -12.719 -9.702 1.00 24.13 ? 404 PHE E CE2 1 ATOM 6254 C CZ . PHE E 2 197 ? -55.550 -12.536 -9.244 1.00 25.71 ? 404 PHE E CZ 1 ATOM 6255 N N . PHE E 2 198 ? -53.102 -13.207 -15.864 1.00 27.79 ? 405 PHE E N 1 ATOM 6256 C CA . PHE E 2 198 ? -52.608 -13.938 -17.007 1.00 28.35 ? 405 PHE E CA 1 ATOM 6257 C C . PHE E 2 198 ? -51.558 -14.938 -16.556 1.00 29.33 ? 405 PHE E C 1 ATOM 6258 O O . PHE E 2 198 ? -50.991 -14.826 -15.453 1.00 32.58 ? 405 PHE E O 1 ATOM 6259 C CB . PHE E 2 198 ? -52.036 -12.992 -18.064 1.00 27.50 ? 405 PHE E CB 1 ATOM 6260 C CG . PHE E 2 198 ? -50.696 -12.435 -17.714 1.00 26.01 ? 405 PHE E CG 1 ATOM 6261 C CD1 . PHE E 2 198 ? -49.531 -13.082 -18.116 1.00 26.54 ? 405 PHE E CD1 1 ATOM 6262 C CD2 . PHE E 2 198 ? -50.594 -11.260 -16.991 1.00 22.08 ? 405 PHE E CD2 1 ATOM 6263 C CE1 . PHE E 2 198 ? -48.288 -12.570 -17.790 1.00 27.54 ? 405 PHE E CE1 1 ATOM 6264 C CE2 . PHE E 2 198 ? -49.361 -10.734 -16.679 1.00 22.53 ? 405 PHE E CE2 1 ATOM 6265 C CZ . PHE E 2 198 ? -48.202 -11.395 -17.064 1.00 26.31 ? 405 PHE E CZ 1 ATOM 6266 N N . LEU E 2 199 ? -51.322 -15.932 -17.401 1.00 24.48 ? 406 LEU E N 1 ATOM 6267 C CA . LEU E 2 199 ? -50.223 -16.871 -17.204 1.00 25.99 ? 406 LEU E CA 1 ATOM 6268 C C . LEU E 2 199 ? -49.691 -17.366 -18.552 1.00 29.21 ? 406 LEU E C 1 ATOM 6269 O O . LEU E 2 199 ? -50.316 -17.145 -19.589 1.00 28.52 ? 406 LEU E O 1 ATOM 6270 C CB . LEU E 2 199 ? -50.644 -18.053 -16.305 1.00 26.85 ? 406 LEU E CB 1 ATOM 6271 C CG . LEU E 2 199 ? -51.783 -19.018 -16.654 1.00 26.82 ? 406 LEU E CG 1 ATOM 6272 C CD1 . LEU E 2 199 ? -51.459 -19.833 -17.894 1.00 28.61 ? 406 LEU E CD1 1 ATOM 6273 C CD2 . LEU E 2 199 ? -52.054 -19.962 -15.487 1.00 27.01 ? 406 LEU E CD2 1 ATOM 6274 N N . TYR E 2 200 ? -48.538 -18.029 -18.513 1.00 27.03 ? 407 TYR E N 1 ATOM 6275 C CA . TYR E 2 200 ? -47.952 -18.663 -19.677 1.00 30.25 ? 407 TYR E CA 1 ATOM 6276 C C . TYR E 2 200 ? -47.642 -20.131 -19.365 1.00 29.96 ? 407 TYR E C 1 ATOM 6277 O O . TYR E 2 200 ? -47.122 -20.454 -18.288 1.00 33.01 ? 407 TYR E O 1 ATOM 6278 C CB . TYR E 2 200 ? -46.654 -17.953 -20.045 1.00 30.92 ? 407 TYR E CB 1 ATOM 6279 C CG . TYR E 2 200 ? -46.812 -16.659 -20.801 1.00 32.00 ? 407 TYR E CG 1 ATOM 6280 C CD1 . TYR E 2 200 ? -46.871 -16.659 -22.188 1.00 32.40 ? 407 TYR E CD1 1 ATOM 6281 C CD2 . TYR E 2 200 ? -46.871 -15.432 -20.134 1.00 28.92 ? 407 TYR E CD2 1 ATOM 6282 C CE1 . TYR E 2 200 ? -46.999 -15.478 -22.897 1.00 30.70 ? 407 TYR E CE1 1 ATOM 6283 C CE2 . TYR E 2 200 ? -46.993 -14.240 -20.834 1.00 29.81 ? 407 TYR E CE2 1 ATOM 6284 C CZ . TYR E 2 200 ? -47.051 -14.282 -22.223 1.00 26.73 ? 407 TYR E CZ 1 ATOM 6285 O OH . TYR E 2 200 ? -47.170 -13.129 -22.941 1.00 26.71 ? 407 TYR E OH 1 ATOM 6286 N N . SER E 2 201 ? -47.968 -21.012 -20.300 1.00 29.86 ? 408 SER E N 1 ATOM 6287 C CA . SER E 2 201 ? -47.613 -22.418 -20.184 1.00 39.43 ? 408 SER E CA 1 ATOM 6288 C C . SER E 2 201 ? -46.663 -22.750 -21.320 1.00 42.93 ? 408 SER E C 1 ATOM 6289 O O . SER E 2 201 ? -46.975 -22.515 -22.490 1.00 48.66 ? 408 SER E O 1 ATOM 6290 C CB . SER E 2 201 ? -48.856 -23.317 -20.240 1.00 41.73 ? 408 SER E CB 1 ATOM 6291 O OG . SER E 2 201 ? -48.549 -24.665 -19.891 1.00 35.91 ? 408 SER E OG 1 ATOM 6292 N N . PHE E 2 202 ? -45.494 -23.270 -20.961 1.00 50.76 ? 409 PHE E N 1 ATOM 6293 C CA . PHE E 2 202 ? -44.481 -23.658 -21.937 1.00 50.85 ? 409 PHE E CA 1 ATOM 6294 C C . PHE E 2 202 ? -44.335 -25.168 -21.964 1.00 53.46 ? 409 PHE E C 1 ATOM 6295 O O . PHE E 2 202 ? -43.958 -25.781 -20.963 1.00 53.16 ? 409 PHE E O 1 ATOM 6296 C CB . PHE E 2 202 ? -43.128 -23.018 -21.610 1.00 43.49 ? 409 PHE E CB 1 ATOM 6297 C CG . PHE E 2 202 ? -43.134 -21.518 -21.682 1.00 55.48 ? 409 PHE E CG 1 ATOM 6298 C CD1 . PHE E 2 202 ? -43.436 -20.754 -20.562 1.00 55.83 ? 409 PHE E CD1 1 ATOM 6299 C CD2 . PHE E 2 202 ? -42.832 -20.866 -22.867 1.00 57.64 ? 409 PHE E CD2 1 ATOM 6300 C CE1 . PHE E 2 202 ? -43.439 -19.369 -20.622 1.00 51.45 ? 409 PHE E CE1 1 ATOM 6301 C CE2 . PHE E 2 202 ? -42.840 -19.483 -22.931 1.00 53.14 ? 409 PHE E CE2 1 ATOM 6302 C CZ . PHE E 2 202 ? -43.142 -18.734 -21.809 1.00 49.11 ? 409 PHE E CZ 1 ATOM 6303 N N . LEU E 2 203 ? -44.655 -25.758 -23.109 1.00 54.67 ? 410 LEU E N 1 ATOM 6304 C CA . LEU E 2 203 ? -44.388 -27.165 -23.346 1.00 60.35 ? 410 LEU E CA 1 ATOM 6305 C C . LEU E 2 203 ? -43.142 -27.280 -24.215 1.00 61.06 ? 410 LEU E C 1 ATOM 6306 O O . LEU E 2 203 ? -43.055 -26.655 -25.280 1.00 54.29 ? 410 LEU E O 1 ATOM 6307 C CB . LEU E 2 203 ? -45.590 -27.856 -24.008 1.00 52.58 ? 410 LEU E CB 1 ATOM 6308 C CG . LEU E 2 203 ? -45.421 -29.316 -24.461 1.00 54.71 ? 410 LEU E CG 1 ATOM 6309 C CD1 . LEU E 2 203 ? -45.273 -30.272 -23.284 1.00 50.75 ? 410 LEU E CD1 1 ATOM 6310 C CD2 . LEU E 2 203 ? -46.579 -29.740 -25.351 1.00 46.24 ? 410 LEU E CD2 1 ATOM 6311 N N . THR E 2 204 ? -42.177 -28.068 -23.748 1.00 56.67 ? 411 THR E N 1 ATOM 6312 C CA . THR E 2 204 ? -40.952 -28.293 -24.499 1.00 54.86 ? 411 THR E CA 1 ATOM 6313 C C . THR E 2 204 ? -41.017 -29.632 -25.226 1.00 57.87 ? 411 THR E C 1 ATOM 6314 O O . THR E 2 204 ? -41.082 -30.689 -24.596 1.00 63.06 ? 411 THR E O 1 ATOM 6315 C CB . THR E 2 204 ? -39.699 -28.216 -23.602 1.00 58.76 ? 411 THR E CB 1 ATOM 6316 O OG1 . THR E 2 204 ? -39.809 -27.092 -22.721 1.00 55.76 ? 411 THR E OG1 1 ATOM 6317 C CG2 . THR E 2 204 ? -38.447 -28.048 -24.450 1.00 52.86 ? 411 THR E CG2 1 ATOM 6318 N N . VAL E 2 205 ? -41.028 -29.566 -26.557 1.00 60.22 ? 412 VAL E N 1 ATOM 6319 C CA . VAL E 2 205 ? -40.984 -30.759 -27.406 1.00 70.69 ? 412 VAL E CA 1 ATOM 6320 C C . VAL E 2 205 ? -39.615 -30.905 -28.082 1.00 96.66 ? 412 VAL E C 1 ATOM 6321 O O . VAL E 2 205 ? -38.936 -29.906 -28.349 1.00 106.06 ? 412 VAL E O 1 ATOM 6322 C CB . VAL E 2 205 ? -42.107 -30.758 -28.476 1.00 67.69 ? 412 VAL E CB 1 ATOM 6323 C CG1 . VAL E 2 205 ? -43.472 -30.942 -27.827 1.00 58.55 ? 412 VAL E CG1 1 ATOM 6324 C CG2 . VAL E 2 205 ? -42.072 -29.489 -29.322 1.00 55.77 ? 412 VAL E CG2 1 ATOM 6325 N N . ASP E 2 206 ? -39.214 -32.149 -28.348 1.00 97.67 ? 413 ASP E N 1 ATOM 6326 C CA . ASP E 2 206 ? -37.972 -32.427 -29.068 1.00 96.35 ? 413 ASP E CA 1 ATOM 6327 C C . ASP E 2 206 ? -38.034 -31.815 -30.468 1.00 101.10 ? 413 ASP E C 1 ATOM 6328 O O . ASP E 2 206 ? -39.064 -31.904 -31.139 1.00 100.92 ? 413 ASP E O 1 ATOM 6329 C CB . ASP E 2 206 ? -37.723 -33.935 -29.147 1.00 89.20 ? 413 ASP E CB 1 ATOM 6330 N N . LYS E 2 207 ? -36.934 -31.187 -30.889 1.00 102.16 ? 414 LYS E N 1 ATOM 6331 C CA . LYS E 2 207 ? -36.866 -30.433 -32.152 1.00 94.41 ? 414 LYS E CA 1 ATOM 6332 C C . LYS E 2 207 ? -37.572 -31.111 -33.331 1.00 91.12 ? 414 LYS E C 1 ATOM 6333 O O . LYS E 2 207 ? -38.382 -30.484 -34.021 1.00 76.40 ? 414 LYS E O 1 ATOM 6334 C CB . LYS E 2 207 ? -35.410 -30.118 -32.517 1.00 79.26 ? 414 LYS E CB 1 ATOM 6335 N N . SER E 2 208 ? -37.264 -32.392 -33.537 1.00 98.57 ? 415 SER E N 1 ATOM 6336 C CA . SER E 2 208 ? -37.853 -33.198 -34.611 1.00 88.31 ? 415 SER E CA 1 ATOM 6337 C C . SER E 2 208 ? -39.364 -33.375 -34.457 1.00 81.18 ? 415 SER E C 1 ATOM 6338 O O . SER E 2 208 ? -40.107 -33.252 -35.432 1.00 80.85 ? 415 SER E O 1 ATOM 6339 C CB . SER E 2 208 ? -37.167 -34.566 -34.687 1.00 75.97 ? 415 SER E CB 1 ATOM 6340 N N . ARG E 2 209 ? -39.805 -33.652 -33.228 1.00 83.82 ? 416 ARG E N 1 ATOM 6341 C CA . ARG E 2 209 ? -41.219 -33.912 -32.925 1.00 77.16 ? 416 ARG E CA 1 ATOM 6342 C C . ARG E 2 209 ? -42.143 -32.802 -33.433 1.00 77.34 ? 416 ARG E C 1 ATOM 6343 O O . ARG E 2 209 ? -43.226 -33.077 -33.953 1.00 84.23 ? 416 ARG E O 1 ATOM 6344 C CB . ARG E 2 209 ? -41.417 -34.145 -31.420 1.00 63.54 ? 416 ARG E CB 1 ATOM 6345 N N . TRP E 2 210 ? -41.703 -31.555 -33.288 1.00 78.87 ? 417 TRP E N 1 ATOM 6346 C CA . TRP E 2 210 ? -42.443 -30.406 -33.800 1.00 89.34 ? 417 TRP E CA 1 ATOM 6347 C C . TRP E 2 210 ? -42.353 -30.316 -35.301 1.00 96.94 ? 417 TRP E C 1 ATOM 6348 O O . TRP E 2 210 ? -43.361 -30.073 -35.976 1.00 86.77 ? 417 TRP E O 1 ATOM 6349 C CB . TRP E 2 210 ? -41.946 -29.121 -33.139 1.00 90.30 ? 417 TRP E CB 1 ATOM 6350 C CG . TRP E 2 210 ? -42.400 -27.841 -33.808 1.00 84.93 ? 417 TRP E CG 1 ATOM 6351 C CD1 . TRP E 2 210 ? -41.627 -26.954 -34.553 1.00 84.04 ? 417 TRP E CD1 1 ATOM 6352 C CD2 . TRP E 2 210 ? -43.751 -27.259 -33.815 1.00 78.81 ? 417 TRP E CD2 1 ATOM 6353 N NE1 . TRP E 2 210 ? -42.383 -25.901 -35.004 1.00 71.97 ? 417 TRP E NE1 1 ATOM 6354 C CE2 . TRP E 2 210 ? -43.660 -26.019 -34.599 1.00 72.89 ? 417 TRP E CE2 1 ATOM 6355 C CE3 . TRP E 2 210 ? -44.978 -27.626 -33.274 1.00 79.64 ? 417 TRP E CE3 1 ATOM 6356 C CZ2 . TRP E 2 210 ? -44.760 -25.202 -34.816 1.00 70.95 ? 417 TRP E CZ2 1 ATOM 6357 C CZ3 . TRP E 2 210 ? -46.079 -26.791 -33.497 1.00 77.85 ? 417 TRP E CZ3 1 ATOM 6358 C CH2 . TRP E 2 210 ? -45.969 -25.608 -34.249 1.00 78.86 ? 417 TRP E CH2 1 ATOM 6359 N N . GLN E 2 211 ? -41.144 -30.526 -35.830 1.00 100.71 ? 418 GLN E N 1 ATOM 6360 C CA . GLN E 2 211 ? -40.874 -30.431 -37.269 1.00 95.71 ? 418 GLN E CA 1 ATOM 6361 C C . GLN E 2 211 ? -41.572 -31.522 -38.084 1.00 96.01 ? 418 GLN E C 1 ATOM 6362 O O . GLN E 2 211 ? -41.787 -31.362 -39.288 1.00 86.88 ? 418 GLN E O 1 ATOM 6363 C CB . GLN E 2 211 ? -39.364 -30.445 -37.538 1.00 87.24 ? 418 GLN E CB 1 ATOM 6364 N N . GLN E 2 212 ? -41.930 -32.619 -37.414 1.00 100.57 ? 419 GLN E N 1 ATOM 6365 C CA . GLN E 2 212 ? -42.647 -33.736 -38.033 1.00 95.24 ? 419 GLN E CA 1 ATOM 6366 C C . GLN E 2 212 ? -44.094 -33.391 -38.413 1.00 98.05 ? 419 GLN E C 1 ATOM 6367 O O . GLN E 2 212 ? -44.740 -34.145 -39.142 1.00 100.78 ? 419 GLN E O 1 ATOM 6368 C CB . GLN E 2 212 ? -42.613 -34.966 -37.119 1.00 82.75 ? 419 GLN E CB 1 ATOM 6369 N N . GLY E 2 213 ? -44.597 -32.262 -37.911 1.00 105.07 ? 420 GLY E N 1 ATOM 6370 C CA . GLY E 2 213 ? -45.923 -31.756 -38.283 1.00 105.40 ? 420 GLY E CA 1 ATOM 6371 C C . GLY E 2 213 ? -47.079 -32.148 -37.373 1.00 100.03 ? 420 GLY E C 1 ATOM 6372 O O . GLY E 2 213 ? -48.245 -31.929 -37.716 1.00 82.09 ? 420 GLY E O 1 ATOM 6373 N N . ASN E 2 214 ? -46.757 -32.718 -36.213 1.00 96.94 ? 421 ASN E N 1 ATOM 6374 C CA . ASN E 2 214 ? -47.758 -33.178 -35.248 1.00 93.56 ? 421 ASN E CA 1 ATOM 6375 C C . ASN E 2 214 ? -48.594 -32.039 -34.670 1.00 98.19 ? 421 ASN E C 1 ATOM 6376 O O . ASN E 2 214 ? -48.122 -30.904 -34.569 1.00 106.56 ? 421 ASN E O 1 ATOM 6377 C CB . ASN E 2 214 ? -47.085 -33.952 -34.108 1.00 95.97 ? 421 ASN E CB 1 ATOM 6378 C CG . ASN E 2 214 ? -46.262 -35.128 -34.603 1.00 93.26 ? 421 ASN E CG 1 ATOM 6379 O OD1 . ASN E 2 214 ? -45.067 -35.224 -34.319 1.00 79.58 ? 421 ASN E OD1 1 ATOM 6380 N ND2 . ASN E 2 214 ? -46.897 -36.028 -35.349 1.00 96.57 ? 421 ASN E ND2 1 ATOM 6381 N N . VAL E 2 215 ? -49.835 -32.353 -34.298 1.00 85.53 ? 422 VAL E N 1 ATOM 6382 C CA . VAL E 2 215 ? -50.741 -31.390 -33.663 1.00 79.06 ? 422 VAL E CA 1 ATOM 6383 C C . VAL E 2 215 ? -50.573 -31.410 -32.136 1.00 69.01 ? 422 VAL E C 1 ATOM 6384 O O . VAL E 2 215 ? -50.457 -32.478 -31.528 1.00 65.64 ? 422 VAL E O 1 ATOM 6385 C CB . VAL E 2 215 ? -52.214 -31.639 -34.087 1.00 79.84 ? 422 VAL E CB 1 ATOM 6386 C CG1 . VAL E 2 215 ? -53.203 -31.091 -33.066 1.00 81.92 ? 422 VAL E CG1 1 ATOM 6387 C CG2 . VAL E 2 215 ? -52.485 -31.039 -35.461 1.00 76.66 ? 422 VAL E CG2 1 ATOM 6388 N N . PHE E 2 216 ? -50.536 -30.225 -31.532 1.00 67.55 ? 423 PHE E N 1 ATOM 6389 C CA . PHE E 2 216 ? -50.446 -30.093 -30.076 1.00 64.48 ? 423 PHE E CA 1 ATOM 6390 C C . PHE E 2 216 ? -51.552 -29.213 -29.513 1.00 68.18 ? 423 PHE E C 1 ATOM 6391 O O . PHE E 2 216 ? -51.918 -28.200 -30.109 1.00 67.00 ? 423 PHE E O 1 ATOM 6392 C CB . PHE E 2 216 ? -49.081 -29.554 -29.654 1.00 62.23 ? 423 PHE E CB 1 ATOM 6393 C CG . PHE E 2 216 ? -47.986 -30.575 -29.712 1.00 60.18 ? 423 PHE E CG 1 ATOM 6394 C CD1 . PHE E 2 216 ? -47.151 -30.654 -30.818 1.00 58.92 ? 423 PHE E CD1 1 ATOM 6395 C CD2 . PHE E 2 216 ? -47.792 -31.463 -28.662 1.00 67.94 ? 423 PHE E CD2 1 ATOM 6396 C CE1 . PHE E 2 216 ? -46.141 -31.599 -30.876 1.00 72.38 ? 423 PHE E CE1 1 ATOM 6397 C CE2 . PHE E 2 216 ? -46.784 -32.413 -28.713 1.00 77.66 ? 423 PHE E CE2 1 ATOM 6398 C CZ . PHE E 2 216 ? -45.958 -32.482 -29.823 1.00 81.44 ? 423 PHE E CZ 1 ATOM 6399 N N . SER E 2 217 ? -52.070 -29.603 -28.354 1.00 71.40 ? 424 SER E N 1 ATOM 6400 C CA . SER E 2 217 ? -53.209 -28.919 -27.760 1.00 61.41 ? 424 SER E CA 1 ATOM 6401 C C . SER E 2 217 ? -52.940 -28.385 -26.358 1.00 61.79 ? 424 SER E C 1 ATOM 6402 O O . SER E 2 217 ? -52.342 -29.063 -25.512 1.00 52.14 ? 424 SER E O 1 ATOM 6403 C CB . SER E 2 217 ? -54.437 -29.830 -27.763 1.00 60.06 ? 424 SER E CB 1 ATOM 6404 O OG . SER E 2 217 ? -54.857 -30.079 -29.091 1.00 62.09 ? 424 SER E OG 1 ATOM 6405 N N . CYS E 2 218 ? -53.383 -27.147 -26.149 1.00 58.20 ? 425 CYS E N 1 ATOM 6406 C CA . CYS E 2 218 ? -53.358 -26.488 -24.857 1.00 49.91 ? 425 CYS E CA 1 ATOM 6407 C C . CYS E 2 218 ? -54.772 -26.484 -24.314 1.00 45.15 ? 425 CYS E C 1 ATOM 6408 O O . CYS E 2 218 ? -55.676 -25.927 -24.933 1.00 44.10 ? 425 CYS E O 1 ATOM 6409 C CB . CYS E 2 218 ? -52.861 -25.049 -25.001 1.00 54.01 ? 425 CYS E CB 1 ATOM 6410 S SG . CYS E 2 218 ? -52.765 -24.162 -23.435 1.00 68.85 ? 425 CYS E SG 1 ATOM 6411 N N . SER E 2 219 ? -54.956 -27.108 -23.157 1.00 52.66 ? 426 SER E N 1 ATOM 6412 C CA . SER E 2 219 ? -56.272 -27.211 -22.541 1.00 57.77 ? 426 SER E CA 1 ATOM 6413 C C . SER E 2 219 ? -56.350 -26.281 -21.354 1.00 53.32 ? 426 SER E C 1 ATOM 6414 O O . SER E 2 219 ? -55.411 -26.199 -20.555 1.00 68.62 ? 426 SER E O 1 ATOM 6415 C CB . SER E 2 219 ? -56.559 -28.648 -22.094 1.00 60.09 ? 426 SER E CB 1 ATOM 6416 O OG . SER E 2 219 ? -56.320 -29.566 -23.145 1.00 56.90 ? 426 SER E OG 1 ATOM 6417 N N . VAL E 2 220 ? -57.470 -25.573 -21.246 1.00 51.10 ? 427 VAL E N 1 ATOM 6418 C CA . VAL E 2 220 ? -57.695 -24.658 -20.131 1.00 48.41 ? 427 VAL E CA 1 ATOM 6419 C C . VAL E 2 220 ? -59.045 -24.962 -19.471 1.00 44.94 ? 427 VAL E C 1 ATOM 6420 O O . VAL E 2 220 ? -60.066 -25.109 -20.151 1.00 42.91 ? 427 VAL E O 1 ATOM 6421 C CB . VAL E 2 220 ? -57.586 -23.177 -20.579 1.00 52.54 ? 427 VAL E CB 1 ATOM 6422 C CG1 . VAL E 2 220 ? -57.887 -22.223 -19.431 1.00 47.93 ? 427 VAL E CG1 1 ATOM 6423 C CG2 . VAL E 2 220 ? -56.198 -22.888 -21.138 1.00 47.72 ? 427 VAL E CG2 1 ATOM 6424 N N . MET E 2 221 ? -59.016 -25.095 -18.147 1.00 42.27 ? 428 MET E N 1 ATOM 6425 C CA . MET E 2 221 ? -60.215 -25.243 -17.335 1.00 46.96 ? 428 MET E CA 1 ATOM 6426 C C . MET E 2 221 ? -60.381 -24.058 -16.391 1.00 45.82 ? 428 MET E C 1 ATOM 6427 O O . MET E 2 221 ? -59.500 -23.754 -15.583 1.00 38.08 ? 428 MET E O 1 ATOM 6428 C CB . MET E 2 221 ? -60.194 -26.554 -16.556 1.00 52.32 ? 428 MET E CB 1 ATOM 6429 C CG . MET E 2 221 ? -60.866 -27.700 -17.288 1.00 53.66 ? 428 MET E CG 1 ATOM 6430 S SD . MET E 2 221 ? -60.822 -29.224 -16.332 1.00 61.99 ? 428 MET E SD 1 ATOM 6431 C CE . MET E 2 221 ? -59.469 -30.090 -17.118 1.00 65.95 ? 428 MET E CE 1 ATOM 6432 N N . HIS E 2 222 ? -61.522 -23.389 -16.525 1.00 46.21 ? 429 HIS E N 1 ATOM 6433 C CA . HIS E 2 222 ? -61.827 -22.161 -15.805 1.00 41.17 ? 429 HIS E CA 1 ATOM 6434 C C . HIS E 2 222 ? -63.314 -21.975 -15.825 1.00 42.26 ? 429 HIS E C 1 ATOM 6435 O O . HIS E 2 222 ? -63.976 -22.335 -16.800 1.00 47.45 ? 429 HIS E O 1 ATOM 6436 C CB . HIS E 2 222 ? -61.130 -20.983 -16.467 1.00 42.66 ? 429 HIS E CB 1 ATOM 6437 C CG . HIS E 2 222 ? -61.189 -19.703 -15.666 1.00 38.60 ? 429 HIS E CG 1 ATOM 6438 N ND1 . HIS E 2 222 ? -62.219 -18.837 -15.759 1.00 36.54 ? 429 HIS E ND1 1 ATOM 6439 C CD2 . HIS E 2 222 ? -60.290 -19.149 -14.755 1.00 37.05 ? 429 HIS E CD2 1 ATOM 6440 C CE1 . HIS E 2 222 ? -61.998 -17.788 -14.944 1.00 35.49 ? 429 HIS E CE1 1 ATOM 6441 N NE2 . HIS E 2 222 ? -60.819 -17.976 -14.330 1.00 30.71 ? 429 HIS E NE2 1 ATOM 6442 N N . GLU E 2 223 ? -63.854 -21.400 -14.757 1.00 37.73 ? 430 GLU E N 1 ATOM 6443 C CA . GLU E 2 223 ? -65.307 -21.324 -14.565 1.00 40.95 ? 430 GLU E CA 1 ATOM 6444 C C . GLU E 2 223 ? -66.030 -20.462 -15.593 1.00 39.93 ? 430 GLU E C 1 ATOM 6445 O O . GLU E 2 223 ? -67.227 -20.635 -15.811 1.00 44.78 ? 430 GLU E O 1 ATOM 6446 C CB . GLU E 2 223 ? -65.633 -20.807 -13.165 1.00 36.19 ? 430 GLU E CB 1 ATOM 6447 C CG . GLU E 2 223 ? -65.127 -19.395 -12.907 1.00 44.57 ? 430 GLU E CG 1 ATOM 6448 C CD . GLU E 2 223 ? -65.704 -18.789 -11.650 1.00 46.38 ? 430 GLU E CD 1 ATOM 6449 O OE1 . GLU E 2 223 ? -65.011 -18.817 -10.614 1.00 66.05 ? 430 GLU E OE1 1 ATOM 6450 O OE2 . GLU E 2 223 ? -66.853 -18.295 -11.696 1.00 51.28 ? 430 GLU E OE2 1 ATOM 6451 N N . ALA E 2 224 ? -65.309 -19.527 -16.203 1.00 35.15 ? 431 ALA E N 1 ATOM 6452 C CA . ALA E 2 224 ? -65.919 -18.545 -17.077 1.00 33.36 ? 431 ALA E CA 1 ATOM 6453 C C . ALA E 2 224 ? -65.817 -18.950 -18.552 1.00 41.35 ? 431 ALA E C 1 ATOM 6454 O O . ALA E 2 224 ? -66.185 -18.189 -19.453 1.00 42.27 ? 431 ALA E O 1 ATOM 6455 C CB . ALA E 2 224 ? -65.312 -17.175 -16.828 1.00 40.91 ? 431 ALA E CB 1 ATOM 6456 N N . LEU E 2 225 ? -65.327 -20.159 -18.791 1.00 37.83 ? 432 LEU E N 1 ATOM 6457 C CA . LEU E 2 225 ? -65.314 -20.714 -20.135 1.00 45.33 ? 432 LEU E CA 1 ATOM 6458 C C . LEU E 2 225 ? -66.581 -21.526 -20.343 1.00 49.18 ? 432 LEU E C 1 ATOM 6459 O O . LEU E 2 225 ? -67.137 -22.061 -19.380 1.00 53.21 ? 432 LEU E O 1 ATOM 6460 C CB . LEU E 2 225 ? -64.098 -21.615 -20.317 1.00 41.92 ? 432 LEU E CB 1 ATOM 6461 C CG . LEU E 2 225 ? -62.718 -20.969 -20.256 1.00 36.09 ? 432 LEU E CG 1 ATOM 6462 C CD1 . LEU E 2 225 ? -61.666 -22.069 -20.222 1.00 29.89 ? 432 LEU E CD1 1 ATOM 6463 C CD2 . LEU E 2 225 ? -62.513 -20.035 -21.440 1.00 39.05 ? 432 LEU E CD2 1 ATOM 6464 N N . HIS E 2 226 ? -67.038 -21.614 -21.591 1.00 50.63 ? 433 HIS E N 1 ATOM 6465 C CA . HIS E 2 226 ? -68.151 -22.498 -21.938 1.00 53.95 ? 433 HIS E CA 1 ATOM 6466 C C . HIS E 2 226 ? -67.793 -23.908 -21.562 1.00 55.03 ? 433 HIS E C 1 ATOM 6467 O O . HIS E 2 226 ? -66.759 -24.427 -21.990 1.00 53.56 ? 433 HIS E O 1 ATOM 6468 C CB . HIS E 2 226 ? -68.487 -22.404 -23.425 1.00 56.62 ? 433 HIS E CB 1 ATOM 6469 N N . ASN E 2 227 ? -68.634 -24.523 -20.731 1.00 51.18 ? 434 ASN E N 1 ATOM 6470 C CA . ASN E 2 227 ? -68.397 -25.871 -20.184 1.00 52.06 ? 434 ASN E CA 1 ATOM 6471 C C . ASN E 2 227 ? -67.190 -25.944 -19.249 1.00 48.86 ? 434 ASN E C 1 ATOM 6472 O O . ASN E 2 227 ? -66.667 -27.035 -18.970 1.00 44.58 ? 434 ASN E O 1 ATOM 6473 C CB . ASN E 2 227 ? -68.282 -26.921 -21.300 1.00 53.42 ? 434 ASN E CB 1 ATOM 6474 C CG . ASN E 2 227 ? -69.491 -26.936 -22.211 1.00 59.46 ? 434 ASN E CG 1 ATOM 6475 O OD1 . ASN E 2 227 ? -70.630 -26.985 -21.743 1.00 56.85 ? 434 ASN E OD1 1 ATOM 6476 N ND2 . ASN E 2 227 ? -69.250 -26.891 -23.521 1.00 52.67 ? 434 ASN E ND2 1 ATOM 6477 N N . ALA E 2 228 ? -66.764 -24.774 -18.767 1.00 43.89 ? 435 ALA E N 1 ATOM 6478 C CA . ALA E 2 228 ? -65.637 -24.651 -17.838 1.00 38.73 ? 435 ALA E CA 1 ATOM 6479 C C . ALA E 2 228 ? -64.352 -25.230 -18.444 1.00 39.18 ? 435 ALA E C 1 ATOM 6480 O O . ALA E 2 228 ? -63.469 -25.687 -17.731 1.00 39.75 ? 435 ALA E O 1 ATOM 6481 C CB . ALA E 2 228 ? -65.973 -25.305 -16.495 1.00 31.55 ? 435 ALA E CB 1 ATOM 6482 N N . TYR E 2 229 ? -64.265 -25.209 -19.774 1.00 37.94 ? 436 TYR E N 1 ATOM 6483 C CA . TYR E 2 229 ? -63.185 -25.870 -20.486 1.00 39.59 ? 436 TYR E CA 1 ATOM 6484 C C . TYR E 2 229 ? -63.084 -25.309 -21.882 1.00 48.52 ? 436 TYR E C 1 ATOM 6485 O O . TYR E 2 229 ? -64.094 -25.017 -22.519 1.00 46.50 ? 436 TYR E O 1 ATOM 6486 C CB . TYR E 2 229 ? -63.422 -27.388 -20.542 1.00 46.61 ? 436 TYR E CB 1 ATOM 6487 C CG . TYR E 2 229 ? -62.505 -28.177 -21.463 1.00 46.66 ? 436 TYR E CG 1 ATOM 6488 C CD1 . TYR E 2 229 ? -62.831 -28.368 -22.810 1.00 55.34 ? 436 TYR E CD1 1 ATOM 6489 C CD2 . TYR E 2 229 ? -61.331 -28.761 -20.983 1.00 54.48 ? 436 TYR E CD2 1 ATOM 6490 C CE1 . TYR E 2 229 ? -62.005 -29.097 -23.657 1.00 53.81 ? 436 TYR E CE1 1 ATOM 6491 C CE2 . TYR E 2 229 ? -60.500 -29.497 -21.821 1.00 55.08 ? 436 TYR E CE2 1 ATOM 6492 C CZ . TYR E 2 229 ? -60.841 -29.658 -23.158 1.00 61.00 ? 436 TYR E CZ 1 ATOM 6493 O OH . TYR E 2 229 ? -60.022 -30.379 -24.004 1.00 65.27 ? 436 TYR E OH 1 ATOM 6494 N N . THR E 2 230 ? -61.847 -25.151 -22.341 1.00 51.44 ? 437 THR E N 1 ATOM 6495 C CA . THR E 2 230 ? -61.577 -24.794 -23.721 1.00 47.08 ? 437 THR E CA 1 ATOM 6496 C C . THR E 2 230 ? -60.241 -25.386 -24.156 1.00 47.29 ? 437 THR E C 1 ATOM 6497 O O . THR E 2 230 ? -59.403 -25.753 -23.320 1.00 40.99 ? 437 THR E O 1 ATOM 6498 C CB . THR E 2 230 ? -61.594 -23.269 -23.941 1.00 50.68 ? 437 THR E CB 1 ATOM 6499 O OG1 . THR E 2 230 ? -61.735 -22.998 -25.340 1.00 48.51 ? 437 THR E OG1 1 ATOM 6500 C CG2 . THR E 2 230 ? -60.311 -22.617 -23.416 1.00 46.17 ? 437 THR E CG2 1 ATOM 6501 N N . GLN E 2 231 ? -60.052 -25.483 -25.467 1.00 42.64 ? 438 GLN E N 1 ATOM 6502 C CA . GLN E 2 231 ? -58.830 -26.037 -26.008 1.00 42.42 ? 438 GLN E CA 1 ATOM 6503 C C . GLN E 2 231 ? -58.416 -25.279 -27.255 1.00 45.39 ? 438 GLN E C 1 ATOM 6504 O O . GLN E 2 231 ? -59.247 -24.954 -28.099 1.00 50.00 ? 438 GLN E O 1 ATOM 6505 C CB . GLN E 2 231 ? -59.027 -27.515 -26.327 1.00 52.90 ? 438 GLN E CB 1 ATOM 6506 C CG . GLN E 2 231 ? -57.739 -28.307 -26.449 1.00 53.58 ? 438 GLN E CG 1 ATOM 6507 C CD . GLN E 2 231 ? -57.997 -29.772 -26.728 1.00 62.80 ? 438 GLN E CD 1 ATOM 6508 O OE1 . GLN E 2 231 ? -58.492 -30.135 -27.798 1.00 56.91 ? 438 GLN E OE1 1 ATOM 6509 N NE2 . GLN E 2 231 ? -57.662 -30.626 -25.764 1.00 54.39 ? 438 GLN E NE2 1 ATOM 6510 N N . LYS E 2 232 ? -57.124 -24.982 -27.349 1.00 53.35 ? 439 LYS E N 1 ATOM 6511 C CA . LYS E 2 232 ? -56.547 -24.384 -28.548 1.00 51.66 ? 439 LYS E CA 1 ATOM 6512 C C . LYS E 2 232 ? -55.376 -25.246 -28.999 1.00 51.07 ? 439 LYS E C 1 ATOM 6513 O O . LYS E 2 232 ? -54.555 -25.677 -28.179 1.00 52.51 ? 439 LYS E O 1 ATOM 6514 C CB . LYS E 2 232 ? -56.092 -22.944 -28.284 1.00 49.00 ? 439 LYS E CB 1 ATOM 6515 C CG . LYS E 2 232 ? -57.189 -22.003 -27.808 1.00 50.60 ? 439 LYS E CG 1 ATOM 6516 C CD . LYS E 2 232 ? -58.011 -21.422 -28.945 1.00 47.53 ? 439 LYS E CD 1 ATOM 6517 C CE . LYS E 2 232 ? -59.141 -20.571 -28.389 1.00 48.59 ? 439 LYS E CE 1 ATOM 6518 N NZ . LYS E 2 232 ? -59.614 -19.562 -29.377 1.00 60.70 ? 439 LYS E NZ 1 ATOM 6519 N N . SER E 2 233 ? -55.311 -25.515 -30.297 1.00 61.67 ? 440 SER E N 1 ATOM 6520 C CA . SER E 2 233 ? -54.323 -26.453 -30.830 1.00 70.53 ? 440 SER E CA 1 ATOM 6521 C C . SER E 2 233 ? -53.355 -25.783 -31.794 1.00 63.38 ? 440 SER E C 1 ATOM 6522 O O . SER E 2 233 ? -53.719 -24.846 -32.501 1.00 55.10 ? 440 SER E O 1 ATOM 6523 C CB . SER E 2 233 ? -55.004 -27.665 -31.479 1.00 72.07 ? 440 SER E CB 1 ATOM 6524 O OG . SER E 2 233 ? -56.035 -27.260 -32.361 1.00 80.56 ? 440 SER E OG 1 ATOM 6525 N N . LEU E 2 234 ? -52.123 -26.284 -31.810 1.00 64.99 ? 441 LEU E N 1 ATOM 6526 C CA . LEU E 2 234 ? -51.029 -25.657 -32.537 1.00 73.00 ? 441 LEU E CA 1 ATOM 6527 C C . LEU E 2 234 ? -50.159 -26.695 -33.252 1.00 77.80 ? 441 LEU E C 1 ATOM 6528 O O . LEU E 2 234 ? -49.717 -27.670 -32.639 1.00 76.87 ? 441 LEU E O 1 ATOM 6529 C CB . LEU E 2 234 ? -50.186 -24.829 -31.560 1.00 73.68 ? 441 LEU E CB 1 ATOM 6530 C CG . LEU E 2 234 ? -49.170 -23.805 -32.074 1.00 74.57 ? 441 LEU E CG 1 ATOM 6531 C CD1 . LEU E 2 234 ? -49.846 -22.624 -32.764 1.00 76.78 ? 441 LEU E CD1 1 ATOM 6532 C CD2 . LEU E 2 234 ? -48.300 -23.328 -30.920 1.00 61.03 ? 441 LEU E CD2 1 ATOM 6533 N N . SER E 2 235 ? -49.929 -26.480 -34.547 1.00 81.69 ? 442 SER E N 1 ATOM 6534 C CA . SER E 2 235 ? -49.055 -27.343 -35.354 1.00 91.76 ? 442 SER E CA 1 ATOM 6535 C C . SER E 2 235 ? -48.226 -26.529 -36.355 1.00 89.84 ? 442 SER E C 1 ATOM 6536 O O . SER E 2 235 ? -48.283 -25.296 -36.358 1.00 85.78 ? 442 SER E O 1 ATOM 6537 C CB . SER E 2 235 ? -49.858 -28.444 -36.063 1.00 94.48 ? 442 SER E CB 1 ATOM 6538 O OG . SER E 2 235 ? -50.731 -27.907 -37.040 1.00 102.82 ? 442 SER E OG 1 ATOM 6539 N N . LEU E 2 236 ? -47.446 -27.221 -37.186 1.00 96.07 ? 443 LEU E N 1 ATOM 6540 C CA . LEU E 2 236 ? -46.587 -26.568 -38.175 1.00 94.20 ? 443 LEU E CA 1 ATOM 6541 C C . LEU E 2 236 ? -47.250 -26.549 -39.551 1.00 83.92 ? 443 LEU E C 1 ATOM 6542 O O . LEU E 2 236 ? -47.379 -25.496 -40.176 1.00 72.39 ? 443 LEU E O 1 ATOM 6543 C CB . LEU E 2 236 ? -45.228 -27.272 -38.251 1.00 94.04 ? 443 LEU E CB 1 ATOM 6544 C CG . LEU E 2 236 ? -43.963 -26.421 -38.425 1.00 94.35 ? 443 LEU E CG 1 ATOM 6545 C CD1 . LEU E 2 236 ? -42.730 -27.290 -38.243 1.00 98.43 ? 443 LEU E CD1 1 ATOM 6546 C CD2 . LEU E 2 236 ? -43.907 -25.698 -39.766 1.00 95.68 ? 443 LEU E CD2 1 ATOM 6547 N N . ASP F 3 1 ? -15.775 -4.465 -26.081 1.00 49.33 ? 1 ASP F N 1 ATOM 6548 C CA . ASP F 3 1 ? -16.974 -3.614 -26.335 1.00 54.11 ? 1 ASP F CA 1 ATOM 6549 C C . ASP F 3 1 ? -17.834 -3.447 -25.082 1.00 52.05 ? 1 ASP F C 1 ATOM 6550 O O . ASP F 3 1 ? -17.715 -4.229 -24.134 1.00 48.52 ? 1 ASP F O 1 ATOM 6551 C CB . ASP F 3 1 ? -17.815 -4.193 -27.485 1.00 61.06 ? 1 ASP F CB 1 ATOM 6552 C CG . ASP F 3 1 ? -18.188 -5.656 -27.269 1.00 67.37 ? 1 ASP F CG 1 ATOM 6553 O OD1 . ASP F 3 1 ? -19.398 -5.960 -27.236 1.00 73.54 ? 1 ASP F OD1 1 ATOM 6554 O OD2 . ASP F 3 1 ? -17.277 -6.503 -27.134 1.00 70.22 ? 1 ASP F OD2 1 ATOM 6555 N N . CYS F 3 2 ? -18.700 -2.431 -25.103 1.00 46.17 ? 2 CYS F N 1 ATOM 6556 C CA . CYS F 3 2 ? -19.623 -2.138 -24.004 1.00 57.96 ? 2 CYS F CA 1 ATOM 6557 C C . CYS F 3 2 ? -21.090 -2.375 -24.380 1.00 54.92 ? 2 CYS F C 1 ATOM 6558 O O . CYS F 3 2 ? -21.438 -2.430 -25.559 1.00 50.74 ? 2 CYS F O 1 ATOM 6559 C CB . CYS F 3 2 ? -19.443 -0.693 -23.535 1.00 52.96 ? 2 CYS F CB 1 ATOM 6560 S SG . CYS F 3 2 ? -17.828 -0.339 -22.806 1.00 69.67 ? 2 CYS F SG 1 ATOM 6561 N N . ALA F 3 3 ? -21.938 -2.531 -23.364 1.00 52.11 ? 3 ALA F N 1 ATOM 6562 C CA . ALA F 3 3 ? -23.385 -2.577 -23.559 1.00 41.95 ? 3 ALA F CA 1 ATOM 6563 C C . ALA F 3 3 ? -24.062 -1.455 -22.787 1.00 40.06 ? 3 ALA F C 1 ATOM 6564 O O . ALA F 3 3 ? -23.696 -1.150 -21.643 1.00 37.14 ? 3 ALA F O 1 ATOM 6565 C CB . ALA F 3 3 ? -23.946 -3.924 -23.150 1.00 42.96 ? 3 ALA F CB 1 ATOM 6566 N N . TRP F 3 4 ? -25.044 -0.834 -23.433 1.00 38.13 ? 4 TRP F N 1 ATOM 6567 C CA . TRP F 3 4 ? -25.783 0.284 -22.855 1.00 40.49 ? 4 TRP F CA 1 ATOM 6568 C C . TRP F 3 4 ? -27.248 -0.046 -22.707 1.00 38.45 ? 4 TRP F C 1 ATOM 6569 O O . TRP F 3 4 ? -27.790 -0.859 -23.452 1.00 37.76 ? 4 TRP F O 1 ATOM 6570 C CB . TRP F 3 4 ? -25.582 1.546 -23.694 1.00 39.87 ? 4 TRP F CB 1 ATOM 6571 C CG . TRP F 3 4 ? -24.136 1.994 -23.779 1.00 47.78 ? 4 TRP F CG 1 ATOM 6572 C CD1 . TRP F 3 4 ? -23.132 1.496 -24.616 1.00 42.10 ? 4 TRP F CD1 1 ATOM 6573 C CD2 . TRP F 3 4 ? -23.481 3.052 -22.989 1.00 46.10 ? 4 TRP F CD2 1 ATOM 6574 N NE1 . TRP F 3 4 ? -21.945 2.153 -24.403 1.00 45.46 ? 4 TRP F NE1 1 ATOM 6575 C CE2 . TRP F 3 4 ? -22.083 3.100 -23.445 1.00 44.40 ? 4 TRP F CE2 1 ATOM 6576 C CE3 . TRP F 3 4 ? -23.897 3.931 -21.991 1.00 45.27 ? 4 TRP F CE3 1 ATOM 6577 C CZ2 . TRP F 3 4 ? -21.163 3.994 -22.909 1.00 52.12 ? 4 TRP F CZ2 1 ATOM 6578 C CZ3 . TRP F 3 4 ? -22.959 4.828 -21.454 1.00 57.69 ? 4 TRP F CZ3 1 ATOM 6579 C CH2 . TRP F 3 4 ? -21.625 4.857 -21.902 1.00 56.42 ? 4 TRP F CH2 1 ATOM 6580 N N . HIS F 3 5 ? -27.891 0.578 -21.724 1.00 42.12 ? 5 HIS F N 1 ATOM 6581 C CA . HIS F 3 5 ? -29.310 0.362 -21.431 1.00 43.47 ? 5 HIS F CA 1 ATOM 6582 C C . HIS F 3 5 ? -29.967 1.684 -21.158 1.00 45.98 ? 5 HIS F C 1 ATOM 6583 O O . HIS F 3 5 ? -29.821 2.251 -20.060 1.00 52.54 ? 5 HIS F O 1 ATOM 6584 C CB . HIS F 3 5 ? -29.479 -0.589 -20.243 1.00 39.79 ? 5 HIS F CB 1 ATOM 6585 C CG . HIS F 3 5 ? -30.890 -0.663 -19.711 1.00 40.25 ? 5 HIS F CG 1 ATOM 6586 N ND1 . HIS F 3 5 ? -31.869 -1.329 -20.348 1.00 42.64 ? 5 HIS F ND1 1 ATOM 6587 C CD2 . HIS F 3 5 ? -31.464 -0.122 -18.562 1.00 47.23 ? 5 HIS F CD2 1 ATOM 6588 C CE1 . HIS F 3 5 ? -33.013 -1.223 -19.649 1.00 41.99 ? 5 HIS F CE1 1 ATOM 6589 N NE2 . HIS F 3 5 ? -32.764 -0.486 -18.553 1.00 53.28 ? 5 HIS F NE2 1 ATOM 6590 N N . LEU F 3 6 ? -30.697 2.174 -22.162 1.00 40.48 ? 6 LEU F N 1 ATOM 6591 C CA . LEU F 3 6 ? -31.307 3.515 -22.157 1.00 45.44 ? 6 LEU F CA 1 ATOM 6592 C C . LEU F 3 6 ? -30.269 4.609 -21.910 1.00 50.21 ? 6 LEU F C 1 ATOM 6593 O O . LEU F 3 6 ? -30.492 5.526 -21.115 1.00 48.30 ? 6 LEU F O 1 ATOM 6594 C CB . LEU F 3 6 ? -32.462 3.615 -21.146 1.00 44.38 ? 6 LEU F CB 1 ATOM 6595 C CG . LEU F 3 6 ? -33.684 2.704 -21.341 1.00 52.77 ? 6 LEU F CG 1 ATOM 6596 C CD1 . LEU F 3 6 ? -34.487 2.634 -20.047 1.00 53.89 ? 6 LEU F CD1 1 ATOM 6597 C CD2 . LEU F 3 6 ? -34.561 3.140 -22.517 1.00 44.60 ? 6 LEU F CD2 1 ATOM 6598 N N . GLY F 3 7 ? -29.131 4.495 -22.596 1.00 57.30 ? 7 GLY F N 1 ATOM 6599 C CA . GLY F 3 7 ? -28.033 5.452 -22.457 1.00 58.18 ? 7 GLY F CA 1 ATOM 6600 C C . GLY F 3 7 ? -27.227 5.343 -21.170 1.00 54.06 ? 7 GLY F C 1 ATOM 6601 O O . GLY F 3 7 ? -26.333 6.156 -20.928 1.00 51.83 ? 7 GLY F O 1 ATOM 6602 N N . GLU F 3 8 ? -27.539 4.344 -20.344 1.00 57.59 ? 8 GLU F N 1 ATOM 6603 C CA . GLU F 3 8 ? -26.783 4.087 -19.117 1.00 54.06 ? 8 GLU F CA 1 ATOM 6604 C C . GLU F 3 8 ? -25.893 2.850 -19.294 1.00 49.93 ? 8 GLU F C 1 ATOM 6605 O O . GLU F 3 8 ? -26.323 1.839 -19.867 1.00 45.03 ? 8 GLU F O 1 ATOM 6606 C CB . GLU F 3 8 ? -27.722 3.927 -17.917 1.00 58.50 ? 8 GLU F CB 1 ATOM 6607 C CG . GLU F 3 8 ? -27.112 4.389 -16.600 1.00 73.96 ? 8 GLU F CG 1 ATOM 6608 C CD . GLU F 3 8 ? -27.943 4.019 -15.381 1.00 87.52 ? 8 GLU F CD 1 ATOM 6609 O OE1 . GLU F 3 8 ? -29.138 3.688 -15.539 1.00 99.63 ? 8 GLU F OE1 1 ATOM 6610 O OE2 . GLU F 3 8 ? -27.399 4.058 -14.256 1.00 81.42 ? 8 GLU F OE2 1 ATOM 6611 N N . LEU F 3 9 ? -24.653 2.937 -18.813 1.00 44.59 ? 9 LEU F N 1 ATOM 6612 C CA . LEU F 3 9 ? -23.665 1.875 -19.037 1.00 43.80 ? 9 LEU F CA 1 ATOM 6613 C C . LEU F 3 9 ? -23.960 0.607 -18.224 1.00 41.57 ? 9 LEU F C 1 ATOM 6614 O O . LEU F 3 9 ? -24.161 0.671 -17.003 1.00 37.36 ? 9 LEU F O 1 ATOM 6615 C CB . LEU F 3 9 ? -22.233 2.383 -18.770 1.00 39.42 ? 9 LEU F CB 1 ATOM 6616 C CG . LEU F 3 9 ? -21.059 1.455 -19.117 1.00 37.05 ? 9 LEU F CG 1 ATOM 6617 C CD1 . LEU F 3 9 ? -20.982 1.150 -20.609 1.00 36.88 ? 9 LEU F CD1 1 ATOM 6618 C CD2 . LEU F 3 9 ? -19.737 2.037 -18.634 1.00 39.33 ? 9 LEU F CD2 1 ATOM 6619 N N . VAL F 3 10 ? -23.979 -0.537 -18.914 1.00 33.87 ? 10 VAL F N 1 ATOM 6620 C CA . VAL F 3 10 ? -24.253 -1.832 -18.277 1.00 35.75 ? 10 VAL F CA 1 ATOM 6621 C C . VAL F 3 10 ? -22.953 -2.502 -17.855 1.00 34.30 ? 10 VAL F C 1 ATOM 6622 O O . VAL F 3 10 ? -22.706 -2.706 -16.669 1.00 36.36 ? 10 VAL F O 1 ATOM 6623 C CB . VAL F 3 10 ? -25.054 -2.794 -19.196 1.00 35.43 ? 10 VAL F CB 1 ATOM 6624 C CG1 . VAL F 3 10 ? -25.377 -4.098 -18.471 1.00 42.46 ? 10 VAL F CG1 1 ATOM 6625 C CG2 . VAL F 3 10 ? -26.338 -2.136 -19.680 1.00 33.12 ? 10 VAL F CG2 1 ATOM 6626 N N . TRP F 3 11 ? -22.125 -2.835 -18.839 1.00 32.80 ? 11 TRP F N 1 ATOM 6627 C CA . TRP F 3 11 ? -20.908 -3.599 -18.611 1.00 36.06 ? 11 TRP F CA 1 ATOM 6628 C C . TRP F 3 11 ? -20.070 -3.519 -19.842 1.00 42.95 ? 11 TRP F C 1 ATOM 6629 O O . TRP F 3 11 ? -20.588 -3.281 -20.940 1.00 44.18 ? 11 TRP F O 1 ATOM 6630 C CB . TRP F 3 11 ? -21.271 -5.051 -18.343 1.00 36.01 ? 11 TRP F CB 1 ATOM 6631 C CG . TRP F 3 11 ? -20.308 -5.841 -17.496 1.00 34.53 ? 11 TRP F CG 1 ATOM 6632 C CD1 . TRP F 3 11 ? -19.351 -6.761 -17.929 1.00 34.27 ? 11 TRP F CD1 1 ATOM 6633 C CD2 . TRP F 3 11 ? -20.214 -5.846 -16.024 1.00 27.51 ? 11 TRP F CD2 1 ATOM 6634 N NE1 . TRP F 3 11 ? -18.685 -7.311 -16.858 1.00 32.31 ? 11 TRP F NE1 1 ATOM 6635 C CE2 . TRP F 3 11 ? -19.155 -6.805 -15.685 1.00 31.80 ? 11 TRP F CE2 1 ATOM 6636 C CE3 . TRP F 3 11 ? -20.877 -5.174 -14.994 1.00 29.36 ? 11 TRP F CE3 1 ATOM 6637 C CZ2 . TRP F 3 11 ? -18.784 -7.060 -14.360 1.00 30.11 ? 11 TRP F CZ2 1 ATOM 6638 C CZ3 . TRP F 3 11 ? -20.494 -5.433 -13.661 1.00 26.69 ? 11 TRP F CZ3 1 ATOM 6639 C CH2 . TRP F 3 11 ? -19.474 -6.360 -13.356 1.00 30.11 ? 11 TRP F CH2 1 ATOM 6640 N N . CYS F 3 12 ? -18.765 -3.714 -19.671 1.00 45.93 ? 12 CYS F N 1 ATOM 6641 C CA . CYS F 3 12 ? -17.838 -3.798 -20.795 1.00 48.24 ? 12 CYS F CA 1 ATOM 6642 C C . CYS F 3 12 ? -16.917 -5.009 -20.634 1.00 46.78 ? 12 CYS F C 1 ATOM 6643 O O . CYS F 3 12 ? -16.538 -5.361 -19.516 1.00 38.80 ? 12 CYS F O 1 ATOM 6644 C CB . CYS F 3 12 ? -17.011 -2.521 -20.890 1.00 49.58 ? 12 CYS F CB 1 ATOM 6645 S SG . CYS F 3 12 ? -17.977 -0.990 -20.866 1.00 54.17 ? 12 CYS F SG 1 ATOM 6646 N N . THR F 3 13 ? -16.599 -5.670 -21.746 1.00 44.72 ? 13 THR F N 1 ATOM 6647 C CA . THR F 3 13 ? -15.532 -6.658 -21.755 1.00 57.84 ? 13 THR F CA 1 ATOM 6648 C C . THR F 3 13 ? -14.262 -5.934 -22.186 1.00 68.39 ? 13 THR F C 1 ATOM 6649 O O . THR F 3 13 ? -14.140 -5.510 -23.336 1.00 67.01 ? 13 THR F O 1 ATOM 6650 C CB . THR F 3 13 ? -15.805 -7.860 -22.689 1.00 63.20 ? 13 THR F CB 1 ATOM 6651 O OG1 . THR F 3 13 ? -16.205 -7.396 -23.985 1.00 72.92 ? 13 THR F OG1 1 ATOM 6652 C CG2 . THR F 3 13 ? -16.880 -8.773 -22.110 1.00 60.92 ? 13 THR F CG2 1 ATOM 6653 O OXT . THR F 3 13 ? -13.346 -5.731 -21.386 1.00 70.86 ? 13 THR F OXT 1 HETATM 6654 C C1 . NAG G 4 . ? -14.036 3.056 -14.318 1.00 43.39 ? 501 NAG A C1 1 HETATM 6655 C C2 . NAG G 4 . ? -14.083 4.579 -14.457 1.00 47.97 ? 501 NAG A C2 1 HETATM 6656 C C3 . NAG G 4 . ? -13.049 5.262 -13.569 1.00 47.62 ? 501 NAG A C3 1 HETATM 6657 C C4 . NAG G 4 . ? -13.035 4.688 -12.141 1.00 43.73 ? 501 NAG A C4 1 HETATM 6658 C C5 . NAG G 4 . ? -13.030 3.147 -12.184 1.00 41.83 ? 501 NAG A C5 1 HETATM 6659 C C6 . NAG G 4 . ? -13.141 2.483 -10.812 1.00 43.32 ? 501 NAG A C6 1 HETATM 6660 C C7 . NAG G 4 . ? -14.840 5.598 -16.531 1.00 55.57 ? 501 NAG A C7 1 HETATM 6661 C C8 . NAG G 4 . ? -14.504 5.989 -17.942 1.00 57.96 ? 501 NAG A C8 1 HETATM 6662 N N2 . NAG G 4 . ? -13.878 4.999 -15.831 1.00 51.03 ? 501 NAG A N2 1 HETATM 6663 O O3 . NAG G 4 . ? -13.335 6.642 -13.572 1.00 52.11 ? 501 NAG A O3 1 HETATM 6664 O O4 . NAG G 4 . ? -11.886 5.131 -11.445 1.00 43.43 ? 501 NAG A O4 1 HETATM 6665 O O5 . NAG G 4 . ? -14.120 2.690 -12.953 1.00 37.70 ? 501 NAG A O5 1 HETATM 6666 O O6 . NAG G 4 . ? -14.309 2.957 -10.199 1.00 43.98 ? 501 NAG A O6 1 HETATM 6667 O O7 . NAG G 4 . ? -15.963 5.827 -16.080 1.00 53.59 ? 501 NAG A O7 1 HETATM 6668 C C1 . NAG H 4 . ? -12.190 6.188 -10.527 1.00 42.06 ? 502 NAG A C1 1 HETATM 6669 C C2 . NAG H 4 . ? -11.344 6.045 -9.268 1.00 39.83 ? 502 NAG A C2 1 HETATM 6670 C C3 . NAG H 4 . ? -11.558 7.239 -8.342 1.00 44.03 ? 502 NAG A C3 1 HETATM 6671 C C4 . NAG H 4 . ? -11.358 8.564 -9.087 1.00 40.95 ? 502 NAG A C4 1 HETATM 6672 C C5 . NAG H 4 . ? -12.263 8.552 -10.316 1.00 43.77 ? 502 NAG A C5 1 HETATM 6673 C C6 . NAG H 4 . ? -12.159 9.830 -11.140 1.00 43.12 ? 502 NAG A C6 1 HETATM 6674 C C7 . NAG H 4 . ? -10.748 3.891 -8.265 1.00 52.38 ? 502 NAG A C7 1 HETATM 6675 C C8 . NAG H 4 . ? -11.258 2.671 -7.549 1.00 45.90 ? 502 NAG A C8 1 HETATM 6676 N N2 . NAG H 4 . ? -11.663 4.811 -8.575 1.00 43.93 ? 502 NAG A N2 1 HETATM 6677 O O3 . NAG H 4 . ? -10.706 7.135 -7.218 1.00 38.46 ? 502 NAG A O3 1 HETATM 6678 O O4 . NAG H 4 . ? -11.759 9.653 -8.293 1.00 38.32 ? 502 NAG A O4 1 HETATM 6679 O O5 . NAG H 4 . ? -11.936 7.440 -11.130 1.00 54.19 ? 502 NAG A O5 1 HETATM 6680 O O6 . NAG H 4 . ? -11.651 9.507 -12.414 1.00 49.44 ? 502 NAG A O6 1 HETATM 6681 O O7 . NAG H 4 . ? -9.547 3.996 -8.533 1.00 53.83 ? 502 NAG A O7 1 HETATM 6682 C C1 . BMA I 5 . ? -10.731 10.185 -7.445 1.00 40.01 ? 503 BMA A C1 1 HETATM 6683 C C2 . BMA I 5 . ? -11.000 11.678 -7.331 1.00 44.00 ? 503 BMA A C2 1 HETATM 6684 C C3 . BMA I 5 . ? -10.100 12.351 -6.301 1.00 49.56 ? 503 BMA A C3 1 HETATM 6685 C C4 . BMA I 5 . ? -10.152 11.621 -4.961 1.00 40.34 ? 503 BMA A C4 1 HETATM 6686 C C5 . BMA I 5 . ? -9.915 10.122 -5.147 1.00 40.14 ? 503 BMA A C5 1 HETATM 6687 C C6 . BMA I 5 . ? -10.096 9.318 -3.856 1.00 36.01 ? 503 BMA A C6 1 HETATM 6688 O O2 . BMA I 5 . ? -12.360 11.860 -6.928 1.00 45.76 ? 503 BMA A O2 1 HETATM 6689 O O3 . BMA I 5 . ? -10.554 13.702 -6.138 1.00 54.36 ? 503 BMA A O3 1 HETATM 6690 O O4 . BMA I 5 . ? -9.138 12.165 -4.124 1.00 47.82 ? 503 BMA A O4 1 HETATM 6691 O O5 . BMA I 5 . ? -10.778 9.569 -6.157 1.00 35.39 ? 503 BMA A O5 1 HETATM 6692 O O6 . BMA I 5 . ? -9.905 7.946 -4.242 1.00 37.24 ? 503 BMA A O6 1 HETATM 6693 C C1 . MAN J 6 . ? -9.879 7.040 -3.130 1.00 43.07 ? 504 MAN A C1 1 HETATM 6694 C C2 . MAN J 6 . ? -9.272 5.716 -3.611 1.00 40.15 ? 504 MAN A C2 1 HETATM 6695 C C3 . MAN J 6 . ? -10.224 5.002 -4.558 1.00 41.09 ? 504 MAN A C3 1 HETATM 6696 C C4 . MAN J 6 . ? -11.586 4.793 -3.880 1.00 43.48 ? 504 MAN A C4 1 HETATM 6697 C C5 . MAN J 6 . ? -12.115 6.118 -3.304 1.00 49.49 ? 504 MAN A C5 1 HETATM 6698 C C6 . MAN J 6 . ? -13.331 5.900 -2.413 1.00 49.26 ? 504 MAN A C6 1 HETATM 6699 O O2 . MAN J 6 . ? -9.068 4.832 -2.537 1.00 30.46 ? 504 MAN A O2 1 HETATM 6700 O O3 . MAN J 6 . ? -9.635 3.776 -4.909 1.00 30.58 ? 504 MAN A O3 1 HETATM 6701 O O4 . MAN J 6 . ? -12.512 4.239 -4.798 1.00 41.96 ? 504 MAN A O4 1 HETATM 6702 O O5 . MAN J 6 . ? -11.143 6.815 -2.523 1.00 50.50 ? 504 MAN A O5 1 HETATM 6703 O O6 . MAN J 6 . ? -13.783 7.169 -1.992 1.00 51.42 ? 504 MAN A O6 1 HETATM 6704 C C1 . NAG K 4 . ? -7.777 5.026 -1.953 1.00 37.65 ? 505 NAG A C1 1 HETATM 6705 C C2 . NAG K 4 . ? -7.875 4.708 -0.465 1.00 40.11 ? 505 NAG A C2 1 HETATM 6706 C C3 . NAG K 4 . ? -6.515 4.890 0.203 1.00 45.99 ? 505 NAG A C3 1 HETATM 6707 C C4 . NAG K 4 . ? -5.387 4.210 -0.584 1.00 46.97 ? 505 NAG A C4 1 HETATM 6708 C C5 . NAG K 4 . ? -5.484 4.560 -2.075 1.00 37.86 ? 505 NAG A C5 1 HETATM 6709 C C6 . NAG K 4 . ? -4.473 3.816 -2.923 1.00 33.53 ? 505 NAG A C6 1 HETATM 6710 C C7 . NAG K 4 . ? -10.077 5.374 0.450 1.00 49.73 ? 505 NAG A C7 1 HETATM 6711 C C8 . NAG K 4 . ? -10.856 6.499 1.089 1.00 39.63 ? 505 NAG A C8 1 HETATM 6712 N N2 . NAG K 4 . ? -8.799 5.637 0.148 1.00 45.10 ? 505 NAG A N2 1 HETATM 6713 O O3 . NAG K 4 . ? -6.577 4.391 1.523 1.00 46.77 ? 505 NAG A O3 1 HETATM 6714 O O4 . NAG K 4 . ? -4.138 4.613 -0.052 1.00 60.15 ? 505 NAG A O4 1 HETATM 6715 O O5 . NAG K 4 . ? -6.775 4.236 -2.552 1.00 41.58 ? 505 NAG A O5 1 HETATM 6716 O O6 . NAG K 4 . ? -4.756 2.439 -2.886 1.00 40.08 ? 505 NAG A O6 1 HETATM 6717 O O7 . NAG K 4 . ? -10.617 4.289 0.234 1.00 41.61 ? 505 NAG A O7 1 HETATM 6718 C C1 . GAL L 7 . ? -3.371 3.474 0.399 1.00 70.00 ? 506 GAL A C1 1 HETATM 6719 C C2 . GAL L 7 . ? -2.016 3.916 0.961 1.00 65.15 ? 506 GAL A C2 1 HETATM 6720 C C3 . GAL L 7 . ? -1.194 2.672 1.304 1.00 54.93 ? 506 GAL A C3 1 HETATM 6721 C C4 . GAL L 7 . ? -1.978 1.702 2.195 1.00 63.17 ? 506 GAL A C4 1 HETATM 6722 C C5 . GAL L 7 . ? -3.359 1.423 1.586 1.00 69.60 ? 506 GAL A C5 1 HETATM 6723 C C6 . GAL L 7 . ? -4.208 0.507 2.464 1.00 69.58 ? 506 GAL A C6 1 HETATM 6724 O O2 . GAL L 7 . ? -1.299 4.717 0.042 1.00 60.13 ? 506 GAL A O2 1 HETATM 6725 O O3 . GAL L 7 . ? 0.004 3.071 1.916 1.00 43.89 ? 506 GAL A O3 1 HETATM 6726 O O4 . GAL L 7 . ? -2.107 2.237 3.498 1.00 57.50 ? 506 GAL A O4 1 HETATM 6727 O O5 . GAL L 7 . ? -4.032 2.655 1.357 1.00 75.97 ? 506 GAL A O5 1 HETATM 6728 O O6 . GAL L 7 . ? -5.515 0.418 1.934 1.00 77.76 ? 506 GAL A O6 1 HETATM 6729 C C1 . FUC M 8 . ? -14.874 2.008 -9.279 1.00 50.01 ? 507 FUC A C1 1 HETATM 6730 C C2 . FUC M 8 . ? -15.527 2.801 -8.153 1.00 52.61 ? 507 FUC A C2 1 HETATM 6731 C C3 . FUC M 8 . ? -16.665 3.640 -8.750 1.00 53.87 ? 507 FUC A C3 1 HETATM 6732 C C4 . FUC M 8 . ? -17.673 2.728 -9.446 1.00 49.32 ? 507 FUC A C4 1 HETATM 6733 C C5 . FUC M 8 . ? -16.986 1.767 -10.418 1.00 47.72 ? 507 FUC A C5 1 HETATM 6734 C C6 . FUC M 8 . ? -17.962 0.683 -10.839 1.00 49.22 ? 507 FUC A C6 1 HETATM 6735 O O2 . FUC M 8 . ? -14.568 3.617 -7.520 1.00 60.53 ? 507 FUC A O2 1 HETATM 6736 O O3 . FUC M 8 . ? -17.321 4.392 -7.757 1.00 50.97 ? 507 FUC A O3 1 HETATM 6737 O O4 . FUC M 8 . ? -18.379 1.993 -8.466 1.00 59.85 ? 507 FUC A O4 1 HETATM 6738 O O5 . FUC M 8 . ? -15.839 1.138 -9.858 1.00 48.78 ? 507 FUC A O5 1 HETATM 6739 C C1 . MAN N 6 . ? -9.562 14.662 -6.560 1.00 55.59 ? 508 MAN A C1 1 HETATM 6740 C C2 . MAN N 6 . ? -9.837 15.977 -5.821 1.00 66.54 ? 508 MAN A C2 1 HETATM 6741 C C3 . MAN N 6 . ? -11.101 16.650 -6.373 1.00 62.21 ? 508 MAN A C3 1 HETATM 6742 C C4 . MAN N 6 . ? -11.098 16.725 -7.905 1.00 66.11 ? 508 MAN A C4 1 HETATM 6743 C C5 . MAN N 6 . ? -10.765 15.350 -8.506 1.00 61.15 ? 508 MAN A C5 1 HETATM 6744 C C6 . MAN N 6 . ? -10.673 15.362 -10.029 1.00 61.21 ? 508 MAN A C6 1 HETATM 6745 O O2 . MAN N 6 . ? -8.714 16.840 -5.885 1.00 65.22 ? 508 MAN A O2 1 HETATM 6746 O O3 . MAN N 6 . ? -11.229 17.932 -5.807 1.00 85.49 ? 508 MAN A O3 1 HETATM 6747 O O4 . MAN N 6 . ? -12.360 17.174 -8.355 1.00 60.33 ? 508 MAN A O4 1 HETATM 6748 O O5 . MAN N 6 . ? -9.541 14.866 -7.965 1.00 61.31 ? 508 MAN A O5 1 HETATM 6749 O O6 . MAN N 6 . ? -11.194 14.152 -10.543 1.00 53.65 ? 508 MAN A O6 1 HETATM 6750 C C1 . NAG O 4 . ? -15.712 29.727 -15.180 1.00 58.88 ? 501 NAG B C1 1 HETATM 6751 C C2 . NAG O 4 . ? -15.899 28.217 -15.344 1.00 65.23 ? 501 NAG B C2 1 HETATM 6752 C C3 . NAG O 4 . ? -17.004 27.717 -14.407 1.00 64.50 ? 501 NAG B C3 1 HETATM 6753 C C4 . NAG O 4 . ? -16.794 28.221 -12.971 1.00 61.18 ? 501 NAG B C4 1 HETATM 6754 C C5 . NAG O 4 . ? -16.582 29.741 -13.007 1.00 64.29 ? 501 NAG B C5 1 HETATM 6755 C C6 . NAG O 4 . ? -16.463 30.397 -11.628 1.00 67.78 ? 501 NAG B C6 1 HETATM 6756 C C7 . NAG O 4 . ? -15.646 26.912 -17.435 1.00 74.33 ? 501 NAG B C7 1 HETATM 6757 C C8 . NAG O 4 . ? -16.068 26.785 -18.871 1.00 68.70 ? 501 NAG B C8 1 HETATM 6758 N N2 . NAG O 4 . ? -16.190 27.918 -16.740 1.00 77.64 ? 501 NAG B N2 1 HETATM 6759 O O3 . NAG O 4 . ? -17.061 26.308 -14.443 1.00 61.92 ? 501 NAG B O3 1 HETATM 6760 O O4 . NAG O 4 . ? -17.938 27.955 -12.189 1.00 62.66 ? 501 NAG B O4 1 HETATM 6761 O O5 . NAG O 4 . ? -15.466 30.047 -13.822 1.00 60.48 ? 501 NAG B O5 1 HETATM 6762 O O6 . NAG O 4 . ? -15.320 29.960 -10.930 1.00 78.20 ? 501 NAG B O6 1 HETATM 6763 O O7 . NAG O 4 . ? -14.842 26.107 -16.967 1.00 78.87 ? 501 NAG B O7 1 HETATM 6764 C C1 . NAG P 4 . ? -17.738 26.845 -11.303 1.00 57.84 ? 502 NAG B C1 1 HETATM 6765 C C2 . NAG P 4 . ? -18.539 27.096 -10.038 1.00 53.60 ? 502 NAG B C2 1 HETATM 6766 C C3 . NAG P 4 . ? -18.425 25.928 -9.064 1.00 55.71 ? 502 NAG B C3 1 HETATM 6767 C C4 . NAG P 4 . ? -18.782 24.605 -9.757 1.00 57.35 ? 502 NAG B C4 1 HETATM 6768 C C5 . NAG P 4 . ? -17.969 24.498 -11.057 1.00 61.63 ? 502 NAG B C5 1 HETATM 6769 C C6 . NAG P 4 . ? -18.271 23.226 -11.847 1.00 60.86 ? 502 NAG B C6 1 HETATM 6770 C C7 . NAG P 4 . ? -19.104 29.295 -9.224 1.00 73.21 ? 502 NAG B C7 1 HETATM 6771 C C8 . NAG P 4 . ? -18.663 30.559 -8.542 1.00 66.68 ? 502 NAG B C8 1 HETATM 6772 N N2 . NAG P 4 . ? -18.180 28.344 -9.393 1.00 59.11 ? 502 NAG B N2 1 HETATM 6773 O O3 . NAG P 4 . ? -19.278 26.197 -7.970 1.00 47.43 ? 502 NAG B O3 1 HETATM 6774 O O4 . NAG P 4 . ? -18.475 23.500 -8.930 1.00 57.21 ? 502 NAG B O4 1 HETATM 6775 O O5 . NAG P 4 . ? -18.190 25.635 -11.879 1.00 59.61 ? 502 NAG B O5 1 HETATM 6776 O O6 . NAG P 4 . ? -18.381 23.503 -13.229 1.00 66.07 ? 502 NAG B O6 1 HETATM 6777 O O7 . NAG P 4 . ? -20.276 29.179 -9.601 1.00 72.31 ? 502 NAG B O7 1 HETATM 6778 C C1 . BMA Q 5 . ? -19.557 23.066 -8.070 1.00 54.70 ? 503 BMA B C1 1 HETATM 6779 C C2 . BMA Q 5 . ? -19.631 21.528 -8.116 1.00 59.64 ? 503 BMA B C2 1 HETATM 6780 C C3 . BMA Q 5 . ? -20.328 20.870 -6.911 1.00 65.32 ? 503 BMA B C3 1 HETATM 6781 C C4 . BMA Q 5 . ? -20.029 21.560 -5.581 1.00 62.04 ? 503 BMA B C4 1 HETATM 6782 C C5 . BMA Q 5 . ? -20.288 23.056 -5.736 1.00 59.11 ? 503 BMA B C5 1 HETATM 6783 C C6 . BMA Q 5 . ? -20.130 23.838 -4.431 1.00 54.45 ? 503 BMA B C6 1 HETATM 6784 O O2 . BMA Q 5 . ? -18.324 20.956 -8.286 1.00 60.90 ? 503 BMA B O2 1 HETATM 6785 O O3 . BMA Q 5 . ? -19.942 19.491 -6.828 1.00 70.17 ? 503 BMA B O3 1 HETATM 6786 O O4 . BMA Q 5 . ? -20.862 21.009 -4.551 1.00 64.22 ? 503 BMA B O4 1 HETATM 6787 O O5 . BMA Q 5 . ? -19.408 23.589 -6.736 1.00 48.72 ? 503 BMA B O5 1 HETATM 6788 O O6 . BMA Q 5 . ? -20.469 25.185 -4.778 1.00 59.38 ? 503 BMA B O6 1 HETATM 6789 C C1 . MAN R 6 . ? -20.499 26.108 -3.671 1.00 64.00 ? 504 MAN B C1 1 HETATM 6790 C C2 . MAN R 6 . ? -21.058 27.437 -4.194 1.00 58.70 ? 504 MAN B C2 1 HETATM 6791 C C3 . MAN R 6 . ? -20.094 27.974 -5.265 1.00 63.64 ? 504 MAN B C3 1 HETATM 6792 C C4 . MAN R 6 . ? -18.626 28.005 -4.810 1.00 69.96 ? 504 MAN B C4 1 HETATM 6793 C C5 . MAN R 6 . ? -18.209 26.806 -3.941 1.00 68.69 ? 504 MAN B C5 1 HETATM 6794 C C6 . MAN R 6 . ? -16.979 27.120 -3.093 1.00 65.49 ? 504 MAN B C6 1 HETATM 6795 O O2 . MAN R 6 . ? -21.223 28.370 -3.142 1.00 46.93 ? 504 MAN B O2 1 HETATM 6796 O O3 . MAN R 6 . ? -20.472 29.247 -5.740 1.00 42.91 ? 504 MAN B O3 1 HETATM 6797 O O4 . MAN R 6 . ? -17.837 28.040 -5.982 1.00 70.60 ? 504 MAN B O4 1 HETATM 6798 O O5 . MAN R 6 . ? -19.239 26.356 -3.065 1.00 72.06 ? 504 MAN B O5 1 HETATM 6799 O O6 . MAN R 6 . ? -16.624 25.978 -2.341 1.00 56.74 ? 504 MAN B O6 1 HETATM 6800 C C1 . NAG S 4 . ? -22.524 28.237 -2.525 1.00 51.55 ? 505 NAG B C1 1 HETATM 6801 C C2 . NAG S 4 . ? -22.453 28.661 -1.054 1.00 53.29 ? 505 NAG B C2 1 HETATM 6802 C C3 . NAG S 4 . ? -23.832 28.696 -0.389 1.00 46.79 ? 505 NAG B C3 1 HETATM 6803 C C4 . NAG S 4 . ? -24.919 29.318 -1.264 1.00 51.55 ? 505 NAG B C4 1 HETATM 6804 C C5 . NAG S 4 . ? -24.820 28.839 -2.719 1.00 50.74 ? 505 NAG B C5 1 HETATM 6805 C C6 . NAG S 4 . ? -25.693 29.669 -3.649 1.00 60.28 ? 505 NAG B C6 1 HETATM 6806 C C7 . NAG S 4 . ? -20.256 27.931 -0.253 1.00 69.42 ? 505 NAG B C7 1 HETATM 6807 C C8 . NAG S 4 . ? -19.485 26.893 0.510 1.00 70.50 ? 505 NAG B C8 1 HETATM 6808 N N2 . NAG S 4 . ? -21.576 27.747 -0.341 1.00 63.09 ? 505 NAG B N2 1 HETATM 6809 O O3 . NAG S 4 . ? -23.779 29.446 0.805 1.00 54.05 ? 505 NAG B O3 1 HETATM 6810 O O4 . NAG S 4 . ? -26.174 28.987 -0.698 1.00 47.21 ? 505 NAG B O4 1 HETATM 6811 O O5 . NAG S 4 . ? -23.504 28.992 -3.200 1.00 54.57 ? 505 NAG B O5 1 HETATM 6812 O O6 . NAG S 4 . ? -25.397 31.044 -3.511 1.00 65.60 ? 505 NAG B O6 1 HETATM 6813 O O7 . NAG S 4 . ? -19.668 28.884 -0.765 1.00 70.87 ? 505 NAG B O7 1 HETATM 6814 C C1 . GAL T 7 . ? -26.958 30.146 -0.338 1.00 56.85 ? 506 GAL B C1 1 HETATM 6815 C C2 . GAL T 7 . ? -28.322 29.664 0.165 1.00 62.89 ? 506 GAL B C2 1 HETATM 6816 C C3 . GAL T 7 . ? -29.214 30.816 0.631 1.00 61.47 ? 506 GAL B C3 1 HETATM 6817 C C4 . GAL T 7 . ? -28.470 31.872 1.464 1.00 72.82 ? 506 GAL B C4 1 HETATM 6818 C C5 . GAL T 7 . ? -27.065 32.165 0.903 1.00 73.68 ? 506 GAL B C5 1 HETATM 6819 C C6 . GAL T 7 . ? -26.239 33.048 1.836 1.00 69.97 ? 506 GAL B C6 1 HETATM 6820 O O2 . GAL T 7 . ? -29.000 28.951 -0.849 1.00 62.00 ? 506 GAL B O2 1 HETATM 6821 O O3 . GAL T 7 . ? -30.282 30.263 1.370 1.00 57.95 ? 506 GAL B O3 1 HETATM 6822 O O4 . GAL T 7 . ? -28.410 31.473 2.823 1.00 71.62 ? 506 GAL B O4 1 HETATM 6823 O O5 . GAL T 7 . ? -26.353 30.965 0.644 1.00 69.44 ? 506 GAL B O5 1 HETATM 6824 O O6 . GAL T 7 . ? -25.112 33.536 1.145 1.00 75.74 ? 506 GAL B O6 1 HETATM 6825 C C1 . MAN U 6 . ? -21.013 18.658 -7.310 1.00 81.28 ? 507 MAN B C1 1 HETATM 6826 C C2 . MAN U 6 . ? -21.328 17.635 -6.211 1.00 88.69 ? 507 MAN B C2 1 HETATM 6827 C C3 . MAN U 6 . ? -20.504 16.358 -6.363 1.00 83.99 ? 507 MAN B C3 1 HETATM 6828 C C4 . MAN U 6 . ? -20.392 15.840 -7.803 1.00 80.10 ? 507 MAN B C4 1 HETATM 6829 C C5 . MAN U 6 . ? -20.967 16.757 -8.892 1.00 83.13 ? 507 MAN B C5 1 HETATM 6830 C C6 . MAN U 6 . ? -22.446 16.485 -9.210 1.00 83.03 ? 507 MAN B C6 1 HETATM 6831 O O2 . MAN U 6 . ? -22.713 17.350 -6.167 1.00 92.85 ? 507 MAN B O2 1 HETATM 6832 O O3 . MAN U 6 . ? -21.055 15.355 -5.538 1.00 86.96 ? 507 MAN B O3 1 HETATM 6833 O O4 . MAN U 6 . ? -19.021 15.676 -8.079 1.00 72.60 ? 507 MAN B O4 1 HETATM 6834 O O5 . MAN U 6 . ? -20.719 18.132 -8.607 1.00 79.27 ? 507 MAN B O5 1 HETATM 6835 O O6 . MAN U 6 . ? -22.733 16.839 -10.545 1.00 83.15 ? 507 MAN B O6 1 HETATM 6836 C C1 . FUC V 8 . ? -14.921 31.001 -10.011 1.00 84.89 ? 508 FUC B C1 1 HETATM 6837 C C2 . FUC V 8 . ? -14.471 30.392 -8.680 1.00 85.06 ? 508 FUC B C2 1 HETATM 6838 C C3 . FUC V 8 . ? -13.078 29.757 -8.796 1.00 89.23 ? 508 FUC B C3 1 HETATM 6839 C C4 . FUC V 8 . ? -12.077 30.675 -9.508 1.00 86.97 ? 508 FUC B C4 1 HETATM 6840 C C5 . FUC V 8 . ? -12.683 31.211 -10.808 1.00 87.86 ? 508 FUC B C5 1 HETATM 6841 C C6 . FUC V 8 . ? -11.738 32.158 -11.541 1.00 74.14 ? 508 FUC B C6 1 HETATM 6842 O O2 . FUC V 8 . ? -15.408 29.426 -8.258 1.00 85.56 ? 508 FUC B O2 1 HETATM 6843 O O3 . FUC V 8 . ? -12.599 29.412 -7.513 1.00 93.99 ? 508 FUC B O3 1 HETATM 6844 O O4 . FUC V 8 . ? -11.705 31.748 -8.665 1.00 86.51 ? 508 FUC B O4 1 HETATM 6845 O O5 . FUC V 8 . ? -13.913 31.862 -10.527 1.00 94.49 ? 508 FUC B O5 1 HETATM 6846 C C1 . NAG W 4 . ? -44.305 -3.146 13.683 1.00 41.94 ? 501 NAG D C1 1 HETATM 6847 C C2 . NAG W 4 . ? -44.516 -4.661 13.739 1.00 43.03 ? 501 NAG D C2 1 HETATM 6848 C C3 . NAG W 4 . ? -43.555 -5.393 12.806 1.00 41.74 ? 501 NAG D C3 1 HETATM 6849 C C4 . NAG W 4 . ? -43.459 -4.756 11.412 1.00 38.84 ? 501 NAG D C4 1 HETATM 6850 C C5 . NAG W 4 . ? -43.320 -3.230 11.524 1.00 36.76 ? 501 NAG D C5 1 HETATM 6851 C C6 . NAG W 4 . ? -43.385 -2.528 10.173 1.00 40.06 ? 501 NAG D C6 1 HETATM 6852 C C7 . NAG W 4 . ? -45.360 -5.700 15.794 1.00 51.64 ? 501 NAG D C7 1 HETATM 6853 C C8 . NAG W 4 . ? -45.038 -6.174 17.190 1.00 40.66 ? 501 NAG D C8 1 HETATM 6854 N N2 . NAG W 4 . ? -44.354 -5.160 15.097 1.00 44.18 ? 501 NAG D N2 1 HETATM 6855 O O3 . NAG W 4 . ? -43.942 -6.739 12.715 1.00 40.08 ? 501 NAG D O3 1 HETATM 6856 O O4 . NAG W 4 . ? -42.301 -5.236 10.761 1.00 39.78 ? 501 NAG D O4 1 HETATM 6857 O O5 . NAG W 4 . ? -44.339 -2.701 12.335 1.00 40.47 ? 501 NAG D O5 1 HETATM 6858 O O6 . NAG W 4 . ? -44.541 -2.917 9.473 1.00 34.96 ? 501 NAG D O6 1 HETATM 6859 O O7 . NAG W 4 . ? -46.509 -5.816 15.355 1.00 44.66 ? 501 NAG D O7 1 HETATM 6860 C C1 . NAG X 4 . ? -42.609 -6.289 9.833 1.00 40.82 ? 502 NAG D C1 1 HETATM 6861 C C2 . NAG X 4 . ? -41.783 -6.123 8.560 1.00 36.92 ? 502 NAG D C2 1 HETATM 6862 C C3 . NAG X 4 . ? -42.052 -7.294 7.611 1.00 37.61 ? 502 NAG D C3 1 HETATM 6863 C C4 . NAG X 4 . ? -41.816 -8.630 8.343 1.00 39.83 ? 502 NAG D C4 1 HETATM 6864 C C5 . NAG X 4 . ? -42.712 -8.624 9.591 1.00 44.11 ? 502 NAG D C5 1 HETATM 6865 C C6 . NAG X 4 . ? -42.663 -9.893 10.430 1.00 38.08 ? 502 NAG D C6 1 HETATM 6866 C C7 . NAG X 4 . ? -41.150 -3.941 7.565 1.00 38.16 ? 502 NAG D C7 1 HETATM 6867 C C8 . NAG X 4 . ? -41.676 -2.665 6.960 1.00 31.36 ? 502 NAG D C8 1 HETATM 6868 N N2 . NAG X 4 . ? -42.069 -4.836 7.948 1.00 34.99 ? 502 NAG D N2 1 HETATM 6869 O O3 . NAG X 4 . ? -41.224 -7.159 6.476 1.00 37.54 ? 502 NAG D O3 1 HETATM 6870 O O4 . NAG X 4 . ? -42.148 -9.765 7.573 1.00 37.89 ? 502 NAG D O4 1 HETATM 6871 O O5 . NAG X 4 . ? -42.339 -7.543 10.414 1.00 46.18 ? 502 NAG D O5 1 HETATM 6872 O O6 . NAG X 4 . ? -41.385 -9.972 11.001 1.00 51.42 ? 502 NAG D O6 1 HETATM 6873 O O7 . NAG X 4 . ? -39.932 -4.111 7.674 1.00 47.53 ? 502 NAG D O7 1 HETATM 6874 C C1 . BMA Y 5 . ? -41.079 -10.298 6.765 1.00 41.58 ? 503 BMA D C1 1 HETATM 6875 C C2 . BMA Y 5 . ? -41.331 -11.788 6.562 1.00 47.16 ? 503 BMA D C2 1 HETATM 6876 C C3 . BMA Y 5 . ? -40.306 -12.403 5.611 1.00 49.82 ? 503 BMA D C3 1 HETATM 6877 C C4 . BMA Y 5 . ? -40.302 -11.651 4.285 1.00 48.47 ? 503 BMA D C4 1 HETATM 6878 C C5 . BMA Y 5 . ? -40.057 -10.172 4.559 1.00 47.50 ? 503 BMA D C5 1 HETATM 6879 C C6 . BMA Y 5 . ? -40.135 -9.354 3.279 1.00 46.58 ? 503 BMA D C6 1 HETATM 6880 O O2 . BMA Y 5 . ? -42.632 -11.935 5.979 1.00 46.64 ? 503 BMA D O2 1 HETATM 6881 O O3 . BMA Y 5 . ? -40.620 -13.781 5.378 1.00 53.94 ? 503 BMA D O3 1 HETATM 6882 O O4 . BMA Y 5 . ? -39.294 -12.187 3.421 1.00 61.38 ? 503 BMA D O4 1 HETATM 6883 O O5 . BMA Y 5 . ? -41.033 -9.664 5.480 1.00 44.61 ? 503 BMA D O5 1 HETATM 6884 O O6 . BMA Y 5 . ? -39.972 -7.988 3.667 1.00 45.39 ? 503 BMA D O6 1 HETATM 6885 C C1 . MAN Z 6 . ? -39.934 -7.136 2.514 1.00 44.40 ? 504 MAN D C1 1 HETATM 6886 C C2 . MAN Z 6 . ? -39.413 -5.763 2.931 1.00 41.86 ? 504 MAN D C2 1 HETATM 6887 C C3 . MAN Z 6 . ? -40.436 -5.072 3.815 1.00 43.88 ? 504 MAN D C3 1 HETATM 6888 C C4 . MAN Z 6 . ? -41.780 -4.972 3.089 1.00 46.96 ? 504 MAN D C4 1 HETATM 6889 C C5 . MAN Z 6 . ? -42.206 -6.379 2.666 1.00 53.59 ? 504 MAN D C5 1 HETATM 6890 C C6 . MAN Z 6 . ? -43.486 -6.401 1.844 1.00 52.87 ? 504 MAN D C6 1 HETATM 6891 O O2 . MAN Z 6 . ? -39.227 -4.951 1.798 1.00 36.37 ? 504 MAN D O2 1 HETATM 6892 O O3 . MAN Z 6 . ? -39.961 -3.807 4.188 1.00 31.49 ? 504 MAN D O3 1 HETATM 6893 O O4 . MAN Z 6 . ? -42.726 -4.396 3.961 1.00 56.60 ? 504 MAN D O4 1 HETATM 6894 O O5 . MAN Z 6 . ? -41.192 -6.993 1.875 1.00 58.98 ? 504 MAN D O5 1 HETATM 6895 O O6 . MAN Z 6 . ? -43.600 -7.705 1.319 1.00 47.48 ? 504 MAN D O6 1 HETATM 6896 C C1 . NAG AA 4 . ? -37.930 -5.180 1.224 1.00 33.33 ? 505 NAG D C1 1 HETATM 6897 C C2 . NAG AA 4 . ? -38.016 -4.911 -0.281 1.00 43.15 ? 505 NAG D C2 1 HETATM 6898 C C3 . NAG AA 4 . ? -36.649 -4.878 -0.954 1.00 40.65 ? 505 NAG D C3 1 HETATM 6899 C C4 . NAG AA 4 . ? -35.607 -4.084 -0.152 1.00 39.00 ? 505 NAG D C4 1 HETATM 6900 C C5 . NAG AA 4 . ? -35.673 -4.555 1.307 1.00 36.15 ? 505 NAG D C5 1 HETATM 6901 C C6 . NAG AA 4 . ? -34.698 -3.856 2.237 1.00 27.86 ? 505 NAG D C6 1 HETATM 6902 C C7 . NAG AA 4 . ? -40.118 -5.610 -1.290 1.00 52.53 ? 505 NAG D C7 1 HETATM 6903 C C8 . NAG AA 4 . ? -40.899 -6.717 -1.942 1.00 48.01 ? 505 NAG D C8 1 HETATM 6904 N N2 . NAG AA 4 . ? -38.869 -5.897 -0.923 1.00 48.93 ? 505 NAG D N2 1 HETATM 6905 O O3 . NAG AA 4 . ? -36.854 -4.328 -2.231 1.00 49.37 ? 505 NAG D O3 1 HETATM 6906 O O4 . NAG AA 4 . ? -34.315 -4.341 -0.675 1.00 44.91 ? 505 NAG D O4 1 HETATM 6907 O O5 . NAG AA 4 . ? -36.973 -4.331 1.804 1.00 37.81 ? 505 NAG D O5 1 HETATM 6908 O O6 . NAG AA 4 . ? -35.020 -2.486 2.307 1.00 32.38 ? 505 NAG D O6 1 HETATM 6909 O O7 . NAG AA 4 . ? -40.629 -4.503 -1.114 1.00 55.62 ? 505 NAG D O7 1 HETATM 6910 C C1 . GAL BA 7 . ? -33.515 -3.154 -0.847 1.00 52.90 ? 506 GAL D C1 1 HETATM 6911 C C2 . GAL BA 7 . ? -32.128 -3.571 -1.374 1.00 57.73 ? 506 GAL D C2 1 HETATM 6912 C C3 . GAL BA 7 . ? -31.302 -2.384 -1.885 1.00 51.70 ? 506 GAL D C3 1 HETATM 6913 C C4 . GAL BA 7 . ? -32.133 -1.407 -2.716 1.00 56.83 ? 506 GAL D C4 1 HETATM 6914 C C5 . GAL BA 7 . ? -33.376 -1.045 -1.908 1.00 62.16 ? 506 GAL D C5 1 HETATM 6915 C C6 . GAL BA 7 . ? -34.223 0.040 -2.558 1.00 61.93 ? 506 GAL D C6 1 HETATM 6916 O O2 . GAL BA 7 . ? -31.371 -4.257 -0.393 1.00 46.90 ? 506 GAL D O2 1 HETATM 6917 O O3 . GAL BA 7 . ? -30.238 -2.889 -2.647 1.00 49.12 ? 506 GAL D O3 1 HETATM 6918 O O4 . GAL BA 7 . ? -32.504 -1.995 -3.948 1.00 50.78 ? 506 GAL D O4 1 HETATM 6919 O O5 . GAL BA 7 . ? -34.144 -2.216 -1.707 1.00 65.56 ? 506 GAL D O5 1 HETATM 6920 O O6 . GAL BA 7 . ? -34.752 0.829 -1.514 1.00 76.03 ? 506 GAL D O6 1 HETATM 6921 C C1 . FUC CA 8 . ? -45.218 -1.777 8.915 1.00 37.14 ? 507 FUC D C1 1 HETATM 6922 C C2 . FUC CA 8 . ? -46.001 -2.237 7.688 1.00 36.52 ? 507 FUC D C2 1 HETATM 6923 C C3 . FUC CA 8 . ? -47.200 -3.117 8.075 1.00 43.55 ? 507 FUC D C3 1 HETATM 6924 C C4 . FUC CA 8 . ? -47.990 -2.525 9.247 1.00 45.04 ? 507 FUC D C4 1 HETATM 6925 C C5 . FUC CA 8 . ? -47.054 -2.062 10.366 1.00 44.67 ? 507 FUC D C5 1 HETATM 6926 C C6 . FUC CA 8 . ? -47.799 -1.396 11.517 1.00 36.07 ? 507 FUC D C6 1 HETATM 6927 O O2 . FUC CA 8 . ? -45.115 -2.974 6.893 1.00 38.79 ? 507 FUC D O2 1 HETATM 6928 O O3 . FUC CA 8 . ? -48.076 -3.256 6.977 1.00 48.88 ? 507 FUC D O3 1 HETATM 6929 O O4 . FUC CA 8 . ? -48.754 -1.428 8.784 1.00 45.17 ? 507 FUC D O4 1 HETATM 6930 O O5 . FUC CA 8 . ? -46.101 -1.160 9.827 1.00 45.35 ? 507 FUC D O5 1 HETATM 6931 C C1 . MAN DA 6 . ? -39.514 -14.616 5.783 1.00 61.83 ? 508 MAN D C1 1 HETATM 6932 C C2 . MAN DA 6 . ? -39.556 -15.944 5.035 1.00 75.32 ? 508 MAN D C2 1 HETATM 6933 C C3 . MAN DA 6 . ? -40.848 -16.682 5.394 1.00 73.04 ? 508 MAN D C3 1 HETATM 6934 C C4 . MAN DA 6 . ? -41.085 -16.755 6.907 1.00 69.53 ? 508 MAN D C4 1 HETATM 6935 C C5 . MAN DA 6 . ? -40.768 -15.428 7.613 1.00 68.81 ? 508 MAN D C5 1 HETATM 6936 C C6 . MAN DA 6 . ? -40.753 -15.554 9.136 1.00 60.15 ? 508 MAN D C6 1 HETATM 6937 O O2 . MAN DA 6 . ? -38.424 -16.723 5.384 1.00 72.71 ? 508 MAN D O2 1 HETATM 6938 O O3 . MAN DA 6 . ? -40.824 -17.979 4.850 1.00 85.81 ? 508 MAN D O3 1 HETATM 6939 O O4 . MAN DA 6 . ? -42.444 -17.060 7.118 1.00 71.55 ? 508 MAN D O4 1 HETATM 6940 O O5 . MAN DA 6 . ? -39.531 -14.894 7.165 1.00 58.09 ? 508 MAN D O5 1 HETATM 6941 O O6 . MAN DA 6 . ? -39.614 -14.905 9.657 1.00 59.98 ? 508 MAN D O6 1 HETATM 6942 I I . IOD EA 9 . ? -37.736 -5.774 -35.944 1.00 35.71 ? 509 IOD D I 1 HETATM 6943 C C1 . NAG FA 4 . ? -46.475 -29.773 15.419 1.00 61.08 ? 501 NAG E C1 1 HETATM 6944 C C2 . NAG FA 4 . ? -46.539 -28.248 15.441 1.00 57.57 ? 501 NAG E C2 1 HETATM 6945 C C3 . NAG FA 4 . ? -47.614 -27.725 14.497 1.00 53.73 ? 501 NAG E C3 1 HETATM 6946 C C4 . NAG FA 4 . ? -47.504 -28.352 13.107 1.00 55.84 ? 501 NAG E C4 1 HETATM 6947 C C5 . NAG FA 4 . ? -47.460 -29.879 13.258 1.00 58.23 ? 501 NAG E C5 1 HETATM 6948 C C6 . NAG FA 4 . ? -47.351 -30.636 11.931 1.00 64.40 ? 501 NAG E C6 1 HETATM 6949 C C7 . NAG FA 4 . ? -45.959 -27.137 17.545 1.00 79.40 ? 501 NAG E C7 1 HETATM 6950 C C8 . NAG FA 4 . ? -46.435 -26.763 18.920 1.00 74.02 ? 501 NAG E C8 1 HETATM 6951 N N2 . NAG FA 4 . ? -46.829 -27.805 16.788 1.00 74.03 ? 501 NAG E N2 1 HETATM 6952 O O3 . NAG FA 4 . ? -47.510 -26.323 14.412 1.00 59.99 ? 501 NAG E O3 1 HETATM 6953 O O4 . NAG FA 4 . ? -48.629 -27.998 12.329 1.00 62.31 ? 501 NAG E O4 1 HETATM 6954 O O5 . NAG FA 4 . ? -46.381 -30.252 14.094 1.00 57.61 ? 501 NAG E O5 1 HETATM 6955 O O6 . NAG FA 4 . ? -46.327 -30.110 11.115 1.00 70.37 ? 501 NAG E O6 1 HETATM 6956 O O7 . NAG FA 4 . ? -44.825 -26.828 17.172 1.00 82.44 ? 501 NAG E O7 1 HETATM 6957 C C1 . NAG GA 4 . ? -48.343 -26.949 11.382 1.00 63.23 ? 502 NAG E C1 1 HETATM 6958 C C2 . NAG GA 4 . ? -49.131 -27.205 10.094 1.00 57.89 ? 502 NAG E C2 1 HETATM 6959 C C3 . NAG GA 4 . ? -48.909 -26.079 9.086 1.00 57.23 ? 502 NAG E C3 1 HETATM 6960 C C4 . NAG GA 4 . ? -49.237 -24.724 9.725 1.00 58.63 ? 502 NAG E C4 1 HETATM 6961 C C5 . NAG GA 4 . ? -48.427 -24.590 11.024 1.00 59.19 ? 502 NAG E C5 1 HETATM 6962 C C6 . NAG GA 4 . ? -48.693 -23.276 11.751 1.00 65.16 ? 502 NAG E C6 1 HETATM 6963 C C7 . NAG GA 4 . ? -49.828 -29.399 9.293 1.00 57.31 ? 502 NAG E C7 1 HETATM 6964 C C8 . NAG GA 4 . ? -49.461 -30.708 8.652 1.00 43.82 ? 502 NAG E C8 1 HETATM 6965 N N2 . NAG GA 4 . ? -48.851 -28.502 9.488 1.00 54.29 ? 502 NAG E N2 1 HETATM 6966 O O3 . NAG GA 4 . ? -49.700 -26.313 7.940 1.00 63.82 ? 502 NAG E O3 1 HETATM 6967 O O4 . NAG GA 4 . ? -48.877 -23.657 8.872 1.00 52.03 ? 502 NAG E O4 1 HETATM 6968 O O5 . NAG GA 4 . ? -48.694 -25.673 11.900 1.00 60.23 ? 502 NAG E O5 1 HETATM 6969 O O6 . NAG GA 4 . ? -47.764 -23.119 12.803 1.00 69.51 ? 502 NAG E O6 1 HETATM 6970 O O7 . NAG GA 4 . ? -51.001 -29.202 9.617 1.00 64.80 ? 502 NAG E O7 1 HETATM 6971 C C1 . BMA HA 5 . ? -49.945 -23.190 8.028 1.00 58.57 ? 503 BMA E C1 1 HETATM 6972 C C2 . BMA HA 5 . ? -49.886 -21.660 7.948 1.00 63.43 ? 503 BMA E C2 1 HETATM 6973 C C3 . BMA HA 5 . ? -50.801 -21.083 6.854 1.00 65.75 ? 503 BMA E C3 1 HETATM 6974 C C4 . BMA HA 5 . ? -50.670 -21.844 5.537 1.00 57.28 ? 503 BMA E C4 1 HETATM 6975 C C5 . BMA HA 5 . ? -50.795 -23.351 5.766 1.00 56.70 ? 503 BMA E C5 1 HETATM 6976 C C6 . BMA HA 5 . ? -50.597 -24.168 4.489 1.00 54.76 ? 503 BMA E C6 1 HETATM 6977 O O2 . BMA HA 5 . ? -48.529 -21.268 7.712 1.00 67.27 ? 503 BMA E O2 1 HETATM 6978 O O3 . BMA HA 5 . ? -50.518 -19.695 6.603 1.00 71.04 ? 503 BMA E O3 1 HETATM 6979 O O4 . BMA HA 5 . ? -51.691 -21.380 4.651 1.00 58.28 ? 503 BMA E O4 1 HETATM 6980 O O5 . BMA HA 5 . ? -49.824 -23.776 6.727 1.00 51.72 ? 503 BMA E O5 1 HETATM 6981 O O6 . BMA HA 5 . ? -50.497 -25.540 4.885 1.00 51.91 ? 503 BMA E O6 1 HETATM 6982 C C1 . MAN IA 6 . ? -50.777 -26.450 3.804 1.00 62.97 ? 504 MAN E C1 1 HETATM 6983 C C2 . MAN IA 6 . ? -51.396 -27.735 4.370 1.00 56.48 ? 504 MAN E C2 1 HETATM 6984 C C3 . MAN IA 6 . ? -50.391 -28.366 5.324 1.00 59.45 ? 504 MAN E C3 1 HETATM 6985 C C4 . MAN IA 6 . ? -49.063 -28.627 4.597 1.00 71.76 ? 504 MAN E C4 1 HETATM 6986 C C5 . MAN IA 6 . ? -48.575 -27.370 3.857 1.00 76.16 ? 504 MAN E C5 1 HETATM 6987 C C6 . MAN IA 6 . ? -47.385 -27.656 2.946 1.00 72.28 ? 504 MAN E C6 1 HETATM 6988 O O2 . MAN IA 6 . ? -51.667 -28.685 3.359 1.00 50.85 ? 504 MAN E O2 1 HETATM 6989 O O3 . MAN IA 6 . ? -50.933 -29.555 5.842 1.00 51.59 ? 504 MAN E O3 1 HETATM 6990 O O4 . MAN IA 6 . ? -48.090 -29.049 5.526 1.00 75.36 ? 504 MAN E O4 1 HETATM 6991 O O5 . MAN IA 6 . ? -49.613 -26.789 3.075 1.00 73.15 ? 504 MAN E O5 1 HETATM 6992 O O6 . MAN IA 6 . ? -47.032 -26.472 2.266 1.00 69.99 ? 504 MAN E O6 1 HETATM 6993 C C1 . NAG JA 4 . ? -52.950 -28.465 2.739 1.00 54.80 ? 505 NAG E C1 1 HETATM 6994 C C2 . NAG JA 4 . ? -52.865 -28.801 1.249 1.00 51.68 ? 505 NAG E C2 1 HETATM 6995 C C3 . NAG JA 4 . ? -54.218 -28.622 0.567 1.00 51.46 ? 505 NAG E C3 1 HETATM 6996 C C4 . NAG JA 4 . ? -55.322 -29.324 1.351 1.00 49.29 ? 505 NAG E C4 1 HETATM 6997 C C5 . NAG JA 4 . ? -55.260 -28.960 2.838 1.00 44.59 ? 505 NAG E C5 1 HETATM 6998 C C6 . NAG JA 4 . ? -56.224 -29.784 3.682 1.00 48.58 ? 505 NAG E C6 1 HETATM 6999 C C7 . NAG JA 4 . ? -50.585 -28.427 0.496 1.00 60.52 ? 505 NAG E C7 1 HETATM 7000 C C8 . NAG JA 4 . ? -49.625 -27.520 -0.223 1.00 62.31 ? 505 NAG E C8 1 HETATM 7001 N N2 . NAG JA 4 . ? -51.850 -28.010 0.579 1.00 54.68 ? 505 NAG E N2 1 HETATM 7002 O O3 . NAG JA 4 . ? -54.168 -29.186 -0.722 1.00 46.86 ? 505 NAG E O3 1 HETATM 7003 O O4 . NAG JA 4 . ? -56.557 -28.969 0.775 1.00 46.07 ? 505 NAG E O4 1 HETATM 7004 O O5 . NAG JA 4 . ? -53.970 -29.239 3.332 1.00 54.42 ? 505 NAG E O5 1 HETATM 7005 O O6 . NAG JA 4 . ? -56.099 -31.147 3.336 1.00 56.21 ? 505 NAG E O6 1 HETATM 7006 O O7 . NAG JA 4 . ? -50.199 -29.494 0.981 1.00 55.23 ? 505 NAG E O7 1 HETATM 7007 C C1 . GAL KA 7 . ? -57.380 -30.115 0.491 1.00 52.64 ? 506 GAL E C1 1 HETATM 7008 C C2 . GAL KA 7 . ? -58.705 -29.593 -0.069 1.00 56.15 ? 506 GAL E C2 1 HETATM 7009 C C3 . GAL KA 7 . ? -59.598 -30.698 -0.640 1.00 61.75 ? 506 GAL E C3 1 HETATM 7010 C C4 . GAL KA 7 . ? -58.822 -31.795 -1.378 1.00 69.45 ? 506 GAL E C4 1 HETATM 7011 C C5 . GAL KA 7 . ? -57.560 -32.189 -0.600 1.00 64.94 ? 506 GAL E C5 1 HETATM 7012 C C6 . GAL KA 7 . ? -56.739 -33.260 -1.311 1.00 66.04 ? 506 GAL E C6 1 HETATM 7013 O O2 . GAL KA 7 . ? -59.404 -28.908 0.952 1.00 50.39 ? 506 GAL E O2 1 HETATM 7014 O O3 . GAL KA 7 . ? -60.541 -30.109 -1.510 1.00 68.63 ? 506 GAL E O3 1 HETATM 7015 O O4 . GAL KA 7 . ? -58.491 -31.353 -2.681 1.00 72.13 ? 506 GAL E O4 1 HETATM 7016 O O5 . GAL KA 7 . ? -56.765 -31.039 -0.386 1.00 57.63 ? 506 GAL E O5 1 HETATM 7017 O O6 . GAL KA 7 . ? -55.571 -33.509 -0.562 1.00 62.29 ? 506 GAL E O6 1 HETATM 7018 C C1 . MAN LA 6 . ? -51.574 -18.843 7.099 1.00 84.24 ? 507 MAN E C1 1 HETATM 7019 C C2 . MAN LA 6 . ? -51.675 -17.565 6.251 1.00 89.11 ? 507 MAN E C2 1 HETATM 7020 C C3 . MAN LA 6 . ? -51.422 -16.300 7.078 1.00 81.15 ? 507 MAN E C3 1 HETATM 7021 C C4 . MAN LA 6 . ? -50.246 -16.450 8.049 1.00 86.32 ? 507 MAN E C4 1 HETATM 7022 C C5 . MAN LA 6 . ? -50.268 -17.782 8.806 1.00 85.46 ? 507 MAN E C5 1 HETATM 7023 C C6 . MAN LA 6 . ? -50.229 -17.552 10.311 1.00 87.24 ? 507 MAN E C6 1 HETATM 7024 O O2 . MAN LA 6 . ? -52.941 -17.471 5.625 1.00 88.87 ? 507 MAN E O2 1 HETATM 7025 O O3 . MAN LA 6 . ? -52.589 -15.969 7.803 1.00 78.64 ? 507 MAN E O3 1 HETATM 7026 O O4 . MAN LA 6 . ? -49.030 -16.344 7.340 1.00 80.56 ? 507 MAN E O4 1 HETATM 7027 O O5 . MAN LA 6 . ? -51.426 -18.535 8.479 1.00 88.22 ? 507 MAN E O5 1 HETATM 7028 O O6 . MAN LA 6 . ? -50.451 -18.776 10.975 1.00 83.62 ? 507 MAN E O6 1 HETATM 7029 C C1 . FUC MA 8 . ? -45.232 -31.043 11.005 1.00 80.37 ? 508 FUC E C1 1 HETATM 7030 C C2 . FUC MA 8 . ? -44.497 -30.789 9.695 1.00 77.75 ? 508 FUC E C2 1 HETATM 7031 C C3 . FUC MA 8 . ? -43.841 -29.410 9.740 1.00 77.29 ? 508 FUC E C3 1 HETATM 7032 C C4 . FUC MA 8 . ? -42.950 -29.264 10.976 1.00 87.86 ? 508 FUC E C4 1 HETATM 7033 C C5 . FUC MA 8 . ? -43.708 -29.673 12.247 1.00 97.65 ? 508 FUC E C5 1 HETATM 7034 C C6 . FUC MA 8 . ? -42.833 -29.671 13.505 1.00 89.43 ? 508 FUC E C6 1 HETATM 7035 O O2 . FUC MA 8 . ? -45.404 -30.858 8.621 1.00 75.46 ? 508 FUC E O2 1 HETATM 7036 O O3 . FUC MA 8 . ? -43.085 -29.219 8.569 1.00 82.91 ? 508 FUC E O3 1 HETATM 7037 O O4 . FUC MA 8 . ? -41.800 -30.065 10.813 1.00 96.57 ? 508 FUC E O4 1 HETATM 7038 O O5 . FUC MA 8 . ? -44.304 -30.956 12.076 1.00 98.95 ? 508 FUC E O5 1 HETATM 7039 O O . HOH NA 10 . ? -22.293 8.208 22.275 1.00 27.46 ? 601 HOH A O 1 HETATM 7040 O O . HOH NA 10 . ? 0.924 3.108 4.263 1.00 30.29 ? 602 HOH A O 1 HETATM 7041 O O . HOH NA 10 . ? 6.091 0.128 -10.259 1.00 38.47 ? 603 HOH A O 1 HETATM 7042 O O . HOH NA 10 . ? 1.509 2.810 -23.279 1.00 39.22 ? 604 HOH A O 1 HETATM 7043 O O . HOH NA 10 . ? -15.161 10.923 11.008 1.00 37.37 ? 605 HOH A O 1 HETATM 7044 O O . HOH NA 10 . ? 4.513 19.251 9.097 1.00 41.83 ? 606 HOH A O 1 HETATM 7045 O O . HOH NA 10 . ? -10.635 23.074 9.759 1.00 51.88 ? 607 HOH A O 1 HETATM 7046 O O . HOH NA 10 . ? 12.843 5.632 9.131 1.00 34.62 ? 608 HOH A O 1 HETATM 7047 O O . HOH NA 10 . ? -10.136 7.361 15.223 1.00 37.50 ? 609 HOH A O 1 HETATM 7048 O O . HOH NA 10 . ? -4.006 -5.515 -7.995 1.00 42.46 ? 610 HOH A O 1 HETATM 7049 O O . HOH NA 10 . ? 11.898 5.258 -11.204 1.00 30.48 ? 611 HOH A O 1 HETATM 7050 O O . HOH NA 10 . ? -4.433 -0.542 11.938 1.00 44.56 ? 612 HOH A O 1 HETATM 7051 O O . HOH NA 10 . ? -14.024 -3.028 -19.359 1.00 50.94 ? 613 HOH A O 1 HETATM 7052 O O . HOH NA 10 . ? -10.424 -2.089 33.506 1.00 41.59 ? 614 HOH A O 1 HETATM 7053 O O . HOH NA 10 . ? -10.072 2.715 -14.535 1.00 29.90 ? 615 HOH A O 1 HETATM 7054 O O . HOH NA 10 . ? -0.865 -3.035 -1.742 1.00 48.90 ? 616 HOH A O 1 HETATM 7055 O O . HOH NA 10 . ? -6.281 3.834 13.727 1.00 41.90 ? 617 HOH A O 1 HETATM 7056 O O . HOH NA 10 . ? -17.675 15.448 31.896 1.00 37.78 ? 618 HOH A O 1 HETATM 7057 O O . HOH NA 10 . ? 8.484 -0.449 -2.809 1.00 35.53 ? 619 HOH A O 1 HETATM 7058 O O . HOH NA 10 . ? -15.348 2.873 34.968 1.00 26.63 ? 620 HOH A O 1 HETATM 7059 O O . HOH NA 10 . ? 6.894 7.765 -16.741 1.00 31.28 ? 621 HOH A O 1 HETATM 7060 O O . HOH NA 10 . ? 2.048 12.336 12.872 1.00 35.96 ? 622 HOH A O 1 HETATM 7061 O O . HOH NA 10 . ? -14.475 7.599 13.158 1.00 36.22 ? 623 HOH A O 1 HETATM 7062 O O . HOH NA 10 . ? -26.363 8.517 25.323 1.00 46.28 ? 624 HOH A O 1 HETATM 7063 O O . HOH NA 10 . ? -9.875 -8.065 -18.527 1.00 43.68 ? 625 HOH A O 1 HETATM 7064 O O . HOH NA 10 . ? -21.389 12.933 28.092 1.00 25.02 ? 626 HOH A O 1 HETATM 7065 O O . HOH NA 10 . ? -19.193 6.840 19.803 1.00 31.61 ? 627 HOH A O 1 HETATM 7066 O O . HOH NA 10 . ? 3.821 10.435 25.248 1.00 39.97 ? 628 HOH A O 1 HETATM 7067 O O . HOH NA 10 . ? -26.273 0.152 33.061 1.00 14.85 ? 629 HOH A O 1 HETATM 7068 O O . HOH NA 10 . ? 12.791 10.520 15.500 1.00 48.78 ? 630 HOH A O 1 HETATM 7069 O O . HOH NA 10 . ? 1.659 18.031 1.838 1.00 36.16 ? 631 HOH A O 1 HETATM 7070 O O . HOH NA 10 . ? 5.041 20.809 20.566 1.00 39.87 ? 632 HOH A O 1 HETATM 7071 O O . HOH NA 10 . ? 11.968 2.710 7.712 1.00 39.76 ? 633 HOH A O 1 HETATM 7072 O O . HOH NA 10 . ? -9.363 4.501 14.034 1.00 47.79 ? 634 HOH A O 1 HETATM 7073 O O . HOH NA 10 . ? -8.049 6.268 -7.390 1.00 48.39 ? 635 HOH A O 1 HETATM 7074 O O . HOH NA 10 . ? -1.220 -2.564 -12.249 1.00 23.86 ? 636 HOH A O 1 HETATM 7075 O O . HOH NA 10 . ? -7.894 8.178 1.037 1.00 34.64 ? 637 HOH A O 1 HETATM 7076 O O . HOH NA 10 . ? -5.420 -7.488 -16.025 1.00 49.36 ? 638 HOH A O 1 HETATM 7077 O O . HOH NA 10 . ? -17.983 12.626 27.465 1.00 29.82 ? 639 HOH A O 1 HETATM 7078 O O . HOH NA 10 . ? -4.900 12.011 10.152 1.00 41.56 ? 640 HOH A O 1 HETATM 7079 O O . HOH NA 10 . ? -20.211 -1.419 25.606 1.00 29.87 ? 641 HOH A O 1 HETATM 7080 O O . HOH NA 10 . ? -2.045 25.591 9.703 1.00 32.58 ? 642 HOH A O 1 HETATM 7081 O O . HOH NA 10 . ? -9.710 -8.028 27.622 1.00 51.21 ? 643 HOH A O 1 HETATM 7082 O O . HOH NA 10 . ? -19.369 -0.567 22.879 1.00 26.47 ? 644 HOH A O 1 HETATM 7083 O O . HOH NA 10 . ? -21.759 7.783 37.819 1.00 38.56 ? 645 HOH A O 1 HETATM 7084 O O . HOH NA 10 . ? 0.785 24.825 13.811 1.00 43.40 ? 646 HOH A O 1 HETATM 7085 O O . HOH NA 10 . ? -3.638 -1.646 16.381 1.00 43.17 ? 647 HOH A O 1 HETATM 7086 O O . HOH NA 10 . ? -1.505 18.546 7.902 1.00 35.88 ? 648 HOH A O 1 HETATM 7087 O O . HOH NA 10 . ? 10.791 18.178 -9.241 1.00 45.49 ? 649 HOH A O 1 HETATM 7088 O O . HOH NA 10 . ? -5.153 13.925 -9.340 1.00 50.83 ? 650 HOH A O 1 HETATM 7089 O O . HOH NA 10 . ? 10.714 10.267 20.509 1.00 38.57 ? 651 HOH A O 1 HETATM 7090 O O . HOH NA 10 . ? 12.564 16.387 -10.442 1.00 44.47 ? 652 HOH A O 1 HETATM 7091 O O . HOH NA 10 . ? 11.409 5.695 -0.395 1.00 38.37 ? 653 HOH A O 1 HETATM 7092 O O . HOH NA 10 . ? 1.022 -7.516 -4.577 1.00 40.68 ? 654 HOH A O 1 HETATM 7093 O O . HOH NA 10 . ? 16.571 2.915 -5.705 1.00 38.09 ? 655 HOH A O 1 HETATM 7094 O O . HOH NA 10 . ? 11.974 14.640 -12.412 1.00 37.98 ? 656 HOH A O 1 HETATM 7095 O O . HOH NA 10 . ? 7.241 0.893 -15.097 1.00 22.60 ? 657 HOH A O 1 HETATM 7096 O O . HOH NA 10 . ? -4.605 13.145 -14.306 1.00 32.71 ? 658 HOH A O 1 HETATM 7097 O O . HOH NA 10 . ? -5.944 13.569 -12.113 1.00 32.24 ? 659 HOH A O 1 HETATM 7098 O O . HOH NA 10 . ? -23.044 -1.976 36.755 1.00 28.68 ? 660 HOH A O 1 HETATM 7099 O O . HOH NA 10 . ? -5.751 13.000 -4.706 1.00 42.17 ? 661 HOH A O 1 HETATM 7100 O O . HOH NA 10 . ? -30.924 14.628 28.979 1.00 46.58 ? 662 HOH A O 1 HETATM 7101 O O . HOH NA 10 . ? 7.820 0.831 -12.609 1.00 28.77 ? 663 HOH A O 1 HETATM 7102 O O . HOH NA 10 . ? -5.124 8.880 1.187 1.00 36.41 ? 664 HOH A O 1 HETATM 7103 O O . HOH OA 10 . ? -31.189 7.079 14.104 1.00 39.54 ? 601 HOH B O 1 HETATM 7104 O O . HOH OA 10 . ? -20.565 29.576 15.272 1.00 42.00 ? 602 HOH B O 1 HETATM 7105 O O . HOH OA 10 . ? -28.667 8.077 8.997 1.00 27.03 ? 603 HOH B O 1 HETATM 7106 O O . HOH OA 10 . ? -31.092 11.788 20.210 1.00 44.69 ? 604 HOH B O 1 HETATM 7107 O O . HOH OA 10 . ? -20.927 26.203 15.537 1.00 48.11 ? 605 HOH B O 1 HETATM 7108 O O . HOH OA 10 . ? -37.787 19.911 2.011 1.00 36.36 ? 606 HOH B O 1 HETATM 7109 O O . HOH OA 10 . ? -34.055 8.955 12.612 1.00 32.66 ? 607 HOH B O 1 HETATM 7110 O O . HOH OA 10 . ? -28.601 36.157 -13.140 1.00 32.63 ? 608 HOH B O 1 HETATM 7111 O O . HOH OA 10 . ? -41.804 28.601 -12.791 1.00 33.08 ? 609 HOH B O 1 HETATM 7112 O O . HOH OA 10 . ? -42.987 29.975 -18.435 1.00 59.77 ? 610 HOH B O 1 HETATM 7113 O O . HOH OA 10 . ? -40.702 31.202 -9.890 1.00 32.60 ? 611 HOH B O 1 HETATM 7114 O O . HOH OA 10 . ? -47.991 17.890 -5.151 1.00 38.68 ? 612 HOH B O 1 HETATM 7115 O O . HOH OA 10 . ? -40.964 19.909 -7.119 1.00 36.14 ? 613 HOH B O 1 HETATM 7116 O O . HOH OA 10 . ? 0.011 28.560 30.846 1.00 42.84 ? 614 HOH B O 1 HETATM 7117 O O . HOH OA 10 . ? -28.736 15.396 7.364 1.00 43.79 ? 615 HOH B O 1 HETATM 7118 O O . HOH OA 10 . ? -31.251 3.128 14.052 1.00 22.41 ? 616 HOH B O 1 HETATM 7119 O O . HOH OA 10 . ? -10.359 19.132 28.855 1.00 46.40 ? 617 HOH B O 1 HETATM 7120 O O . HOH OA 10 . ? -33.244 39.108 -7.346 1.00 49.05 ? 618 HOH B O 1 HETATM 7121 O O . HOH OA 10 . ? -31.329 9.198 12.667 1.00 45.59 ? 619 HOH B O 1 HETATM 7122 O O . HOH OA 10 . ? -18.784 8.042 10.549 1.00 41.28 ? 620 HOH B O 1 HETATM 7123 O O . HOH OA 10 . ? -37.401 32.646 -16.002 1.00 32.32 ? 621 HOH B O 1 HETATM 7124 O O . HOH OA 10 . ? -26.355 20.410 -7.787 1.00 42.03 ? 622 HOH B O 1 HETATM 7125 O O . HOH OA 10 . ? -21.971 24.536 -0.625 1.00 40.71 ? 623 HOH B O 1 HETATM 7126 O O . HOH OA 10 . ? -24.781 36.751 2.762 1.00 50.89 ? 624 HOH B O 1 HETATM 7127 O O . HOH OA 10 . ? -37.522 32.813 -13.451 1.00 37.89 ? 625 HOH B O 1 HETATM 7128 O O . HOH PA 10 . ? 15.789 2.854 22.632 1.00 44.94 ? 101 HOH C O 1 HETATM 7129 O O . HOH QA 10 . ? -40.642 -2.722 13.964 1.00 49.18 ? 601 HOH D O 1 HETATM 7130 O O . HOH QA 10 . ? -51.198 -1.638 9.341 1.00 31.45 ? 602 HOH D O 1 HETATM 7131 O O . HOH QA 10 . ? -35.674 -1.151 -22.120 1.00 42.41 ? 603 HOH D O 1 HETATM 7132 O O . HOH QA 10 . ? -44.994 -3.203 -35.393 1.00 30.27 ? 604 HOH D O 1 HETATM 7133 O O . HOH QA 10 . ? -23.665 -7.512 16.450 1.00 30.96 ? 605 HOH D O 1 HETATM 7134 O O . HOH QA 10 . ? -24.220 0.098 9.904 1.00 32.26 ? 606 HOH D O 1 HETATM 7135 O O . HOH QA 10 . ? -38.254 1.343 -30.918 1.00 35.52 ? 607 HOH D O 1 HETATM 7136 O O . HOH QA 10 . ? -44.389 -7.887 -13.772 1.00 34.05 ? 608 HOH D O 1 HETATM 7137 O O . HOH QA 10 . ? -34.467 5.452 7.515 1.00 33.50 ? 609 HOH D O 1 HETATM 7138 O O . HOH QA 10 . ? -24.798 -18.972 -9.598 1.00 41.35 ? 610 HOH D O 1 HETATM 7139 O O . HOH QA 10 . ? -46.687 -15.442 -31.751 1.00 36.17 ? 611 HOH D O 1 HETATM 7140 O O . HOH QA 10 . ? -24.732 -12.999 -24.795 1.00 36.57 ? 612 HOH D O 1 HETATM 7141 O O . HOH QA 10 . ? -32.860 -4.994 -30.621 1.00 34.17 ? 613 HOH D O 1 HETATM 7142 O O . HOH QA 10 . ? -12.564 -7.574 13.692 1.00 38.39 ? 614 HOH D O 1 HETATM 7143 O O . HOH QA 10 . ? -39.840 -7.418 -15.764 1.00 33.90 ? 615 HOH D O 1 HETATM 7144 O O . HOH QA 10 . ? -44.250 2.991 19.024 1.00 47.93 ? 616 HOH D O 1 HETATM 7145 O O . HOH QA 10 . ? -54.710 0.533 -21.488 1.00 35.69 ? 617 HOH D O 1 HETATM 7146 O O . HOH QA 10 . ? -29.565 -30.470 -15.890 1.00 34.07 ? 618 HOH D O 1 HETATM 7147 O O . HOH QA 10 . ? -34.076 -8.397 -32.469 1.00 26.37 ? 619 HOH D O 1 HETATM 7148 O O . HOH QA 10 . ? -49.064 -6.025 -19.759 1.00 43.59 ? 620 HOH D O 1 HETATM 7149 O O . HOH QA 10 . ? -45.680 1.518 10.145 1.00 41.53 ? 621 HOH D O 1 HETATM 7150 O O . HOH QA 10 . ? -42.024 -8.452 -39.187 1.00 47.26 ? 622 HOH D O 1 HETATM 7151 O O . HOH QA 10 . ? -35.635 1.731 -28.079 1.00 34.24 ? 623 HOH D O 1 HETATM 7152 O O . HOH QA 10 . ? -31.763 2.595 11.504 1.00 19.73 ? 624 HOH D O 1 HETATM 7153 O O . HOH QA 10 . ? -35.295 -4.524 21.709 1.00 31.24 ? 625 HOH D O 1 HETATM 7154 O O . HOH QA 10 . ? -19.154 -13.564 5.610 1.00 36.36 ? 626 HOH D O 1 HETATM 7155 O O . HOH QA 10 . ? -46.002 0.887 -22.241 1.00 36.97 ? 627 HOH D O 1 HETATM 7156 O O . HOH QA 10 . ? -43.867 3.844 -20.516 1.00 35.37 ? 628 HOH D O 1 HETATM 7157 O O . HOH QA 10 . ? -34.025 -14.421 -30.527 1.00 46.50 ? 629 HOH D O 1 HETATM 7158 O O . HOH QA 10 . ? -37.015 2.041 8.114 1.00 32.59 ? 630 HOH D O 1 HETATM 7159 O O . HOH QA 10 . ? -16.553 -5.323 -8.741 1.00 43.25 ? 631 HOH D O 1 HETATM 7160 O O . HOH QA 10 . ? -18.303 -6.269 -1.493 1.00 41.45 ? 632 HOH D O 1 HETATM 7161 O O . HOH QA 10 . ? -47.640 -12.747 -27.968 1.00 26.21 ? 633 HOH D O 1 HETATM 7162 O O . HOH QA 10 . ? -28.943 -24.997 -14.636 1.00 32.89 ? 634 HOH D O 1 HETATM 7163 O O . HOH QA 10 . ? -46.246 4.838 -30.719 1.00 40.96 ? 635 HOH D O 1 HETATM 7164 O O . HOH QA 10 . ? -27.094 -21.319 -3.148 1.00 40.08 ? 636 HOH D O 1 HETATM 7165 O O . HOH QA 10 . ? -47.861 -4.021 13.514 1.00 39.24 ? 637 HOH D O 1 HETATM 7166 O O . HOH QA 10 . ? -19.576 -2.378 8.367 1.00 33.79 ? 638 HOH D O 1 HETATM 7167 O O . HOH QA 10 . ? -26.248 -0.321 30.634 1.00 29.21 ? 639 HOH D O 1 HETATM 7168 O O . HOH QA 10 . ? -39.850 1.697 -34.868 1.00 43.28 ? 640 HOH D O 1 HETATM 7169 O O . HOH QA 10 . ? -43.539 7.136 19.715 1.00 50.25 ? 641 HOH D O 1 HETATM 7170 O O . HOH QA 10 . ? -19.200 -10.151 -20.467 1.00 46.08 ? 642 HOH D O 1 HETATM 7171 O O . HOH QA 10 . ? -44.337 -4.176 -14.282 1.00 38.43 ? 643 HOH D O 1 HETATM 7172 O O . HOH QA 10 . ? -45.306 -9.329 -39.395 1.00 45.82 ? 644 HOH D O 1 HETATM 7173 O O . HOH QA 10 . ? -51.207 -13.221 -28.264 1.00 35.25 ? 645 HOH D O 1 HETATM 7174 O O . HOH QA 10 . ? -18.499 -4.660 11.365 1.00 43.52 ? 646 HOH D O 1 HETATM 7175 O O . HOH QA 10 . ? -34.583 -13.107 13.182 1.00 32.81 ? 647 HOH D O 1 HETATM 7176 O O . HOH QA 10 . ? -28.300 1.342 16.489 1.00 32.58 ? 648 HOH D O 1 HETATM 7177 O O . HOH QA 10 . ? -38.339 -6.427 6.777 1.00 43.17 ? 649 HOH D O 1 HETATM 7178 O O . HOH QA 10 . ? -31.868 -25.325 -9.817 1.00 37.72 ? 650 HOH D O 1 HETATM 7179 O O . HOH QA 10 . ? -39.827 2.513 8.223 1.00 41.15 ? 651 HOH D O 1 HETATM 7180 O O . HOH QA 10 . ? -27.787 -12.130 -13.070 1.00 30.67 ? 652 HOH D O 1 HETATM 7181 O O . HOH QA 10 . ? -30.910 -15.502 -27.177 1.00 38.20 ? 653 HOH D O 1 HETATM 7182 O O . HOH QA 10 . ? -36.835 -5.846 -14.402 1.00 36.50 ? 654 HOH D O 1 HETATM 7183 O O . HOH QA 10 . ? -33.489 -7.200 -4.128 1.00 36.21 ? 655 HOH D O 1 HETATM 7184 O O . HOH QA 10 . ? -31.610 -0.338 -29.811 1.00 45.69 ? 656 HOH D O 1 HETATM 7185 O O . HOH QA 10 . ? -23.228 -0.869 14.603 1.00 23.59 ? 657 HOH D O 1 HETATM 7186 O O . HOH QA 10 . ? -49.820 1.315 -26.371 1.00 44.35 ? 658 HOH D O 1 HETATM 7187 O O . HOH QA 10 . ? -18.367 -14.108 12.810 1.00 47.05 ? 659 HOH D O 1 HETATM 7188 O O . HOH QA 10 . ? -19.203 -17.169 8.997 1.00 42.70 ? 660 HOH D O 1 HETATM 7189 O O . HOH QA 10 . ? -33.453 -15.582 13.003 1.00 39.11 ? 661 HOH D O 1 HETATM 7190 O O . HOH QA 10 . ? -36.294 -12.685 4.225 1.00 45.19 ? 662 HOH D O 1 HETATM 7191 O O . HOH QA 10 . ? -31.606 -15.627 -30.076 1.00 58.78 ? 663 HOH D O 1 HETATM 7192 O O . HOH QA 10 . ? -38.425 -9.148 -0.933 1.00 32.43 ? 664 HOH D O 1 HETATM 7193 O O . HOH QA 10 . ? -22.461 -0.625 12.085 1.00 36.49 ? 665 HOH D O 1 HETATM 7194 O O . HOH QA 10 . ? -45.353 -8.217 -11.357 1.00 43.62 ? 666 HOH D O 1 HETATM 7195 O O . HOH QA 10 . ? -47.622 -4.789 21.784 1.00 43.79 ? 667 HOH D O 1 HETATM 7196 O O . HOH RA 10 . ? -56.311 -8.322 -19.619 1.00 36.55 ? 601 HOH E O 1 HETATM 7197 O O . HOH RA 10 . ? -72.496 -28.310 11.990 1.00 38.19 ? 602 HOH E O 1 HETATM 7198 O O . HOH RA 10 . ? -50.251 -30.809 15.861 1.00 56.38 ? 603 HOH E O 1 HETATM 7199 O O . HOH RA 10 . ? -60.909 -11.473 -20.471 1.00 39.34 ? 604 HOH E O 1 HETATM 7200 O O . HOH RA 10 . ? -73.307 -27.766 -7.716 1.00 45.23 ? 605 HOH E O 1 HETATM 7201 O O . HOH RA 10 . ? -50.294 -25.921 -15.502 1.00 38.86 ? 606 HOH E O 1 HETATM 7202 O O . HOH RA 10 . ? -44.938 -22.512 -11.561 1.00 42.92 ? 607 HOH E O 1 HETATM 7203 O O . HOH RA 10 . ? -57.860 -7.780 -9.275 1.00 37.03 ? 608 HOH E O 1 HETATM 7204 O O . HOH RA 10 . ? -54.957 -10.264 -18.076 1.00 36.95 ? 609 HOH E O 1 HETATM 7205 O O . HOH RA 10 . ? -63.543 -34.677 17.394 1.00 46.84 ? 610 HOH E O 1 HETATM 7206 O O . HOH RA 10 . ? -60.688 -3.013 -14.787 1.00 28.44 ? 611 HOH E O 1 HETATM 7207 O O . HOH RA 10 . ? -53.189 -4.330 -11.202 1.00 36.67 ? 612 HOH E O 1 HETATM 7208 O O . HOH RA 10 . ? -48.517 -7.787 -10.896 1.00 29.83 ? 613 HOH E O 1 HETATM 7209 O O . HOH RA 10 . ? -60.760 -7.069 -14.782 1.00 41.13 ? 614 HOH E O 1 HETATM 7210 O O . HOH RA 10 . ? -71.306 -19.458 6.815 1.00 40.07 ? 615 HOH E O 1 HETATM 7211 O O . HOH RA 10 . ? -42.450 -20.243 -28.621 1.00 49.02 ? 616 HOH E O 1 HETATM 7212 O O . HOH RA 10 . ? -59.339 -35.956 12.907 1.00 33.15 ? 617 HOH E O 1 HETATM 7213 O O . HOH RA 10 . ? -50.164 -22.141 -12.860 1.00 42.33 ? 618 HOH E O 1 HETATM 7214 O O . HOH RA 10 . ? -56.141 -21.531 -7.615 1.00 41.99 ? 619 HOH E O 1 HETATM 7215 O O . HOH RA 10 . ? -77.878 -17.845 4.194 1.00 41.09 ? 620 HOH E O 1 HETATM 7216 O O . HOH RA 10 . ? -61.524 -15.456 -1.346 1.00 49.70 ? 621 HOH E O 1 HETATM 7217 O O . HOH RA 10 . ? -52.230 -25.035 0.828 1.00 34.59 ? 622 HOH E O 1 HETATM 7218 O O . HOH RA 10 . ? -49.460 -10.817 -9.030 1.00 40.70 ? 623 HOH E O 1 HETATM 7219 O O . HOH RA 10 . ? -71.411 -30.891 9.937 1.00 41.98 ? 624 HOH E O 1 HETATM 7220 O O . HOH RA 10 . ? -68.252 -32.539 15.678 1.00 33.74 ? 625 HOH E O 1 HETATM 7221 O O . HOH RA 10 . ? -58.253 -14.802 -7.041 1.00 39.57 ? 626 HOH E O 1 HETATM 7222 O O . HOH RA 10 . ? -52.882 -26.843 -13.662 1.00 41.38 ? 627 HOH E O 1 HETATM 7223 O O . HOH RA 10 . ? -61.120 -9.069 -13.244 1.00 32.26 ? 628 HOH E O 1 HETATM 7224 O O . HOH RA 10 . ? -56.343 -25.823 -0.630 1.00 44.02 ? 629 HOH E O 1 HETATM 7225 O O . HOH RA 10 . ? -57.125 -28.210 -18.077 1.00 45.22 ? 630 HOH E O 1 HETATM 7226 O O . HOH RA 10 . ? -70.449 -12.447 -14.618 1.00 47.74 ? 631 HOH E O 1 HETATM 7227 O O . HOH RA 10 . ? -61.929 -40.129 5.003 1.00 49.28 ? 632 HOH E O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ASP 1 221 ? ? ? A . n A 1 2 LYS 2 222 ? ? ? A . n A 1 3 THR 3 223 ? ? ? A . n A 1 4 HIS 4 224 ? ? ? A . n A 1 5 THR 5 225 ? ? ? A . n A 1 6 CYS 6 226 ? ? ? A . n A 1 7 PRO 7 227 ? ? ? A . n A 1 8 PRO 8 228 ? ? ? A . n A 1 9 CYS 9 229 ? ? ? A . n A 1 10 PRO 10 230 ? ? ? A . n A 1 11 ALA 11 231 ? ? ? A . n A 1 12 PRO 12 232 ? ? ? A . n A 1 13 GLU 13 233 ? ? ? A . n A 1 14 LEU 14 234 ? ? ? A . n A 1 15 LEU 15 235 ? ? ? A . n A 1 16 GLY 16 236 ? ? ? A . n A 1 17 GLY 17 237 237 GLY GLY A . n A 1 18 PRO 18 238 238 PRO PRO A . n A 1 19 SER 19 239 239 SER SER A . n A 1 20 VAL 20 240 240 VAL VAL A . n A 1 21 PHE 21 241 241 PHE PHE A . n A 1 22 LEU 22 242 242 LEU LEU A . n A 1 23 PHE 23 243 243 PHE PHE A . n A 1 24 PRO 24 244 244 PRO PRO A . n A 1 25 PRO 25 245 245 PRO PRO A . n A 1 26 LYS 26 246 246 LYS LYS A . n A 1 27 PRO 27 247 247 PRO PRO A . n A 1 28 LYS 28 248 248 LYS LYS A . n A 1 29 ASP 29 249 249 ASP ASP A . n A 1 30 THR 30 250 250 THR THR A . n A 1 31 LEU 31 251 251 LEU LEU A . n A 1 32 MET 32 252 252 MET MET A . n A 1 33 ILE 33 253 253 ILE ILE A . n A 1 34 SER 34 254 254 SER SER A . n A 1 35 ARG 35 255 255 ARG ARG A . n A 1 36 THR 36 256 256 THR THR A . n A 1 37 PRO 37 257 257 PRO PRO A . n A 1 38 GLU 38 258 258 GLU GLU A . n A 1 39 VAL 39 259 259 VAL VAL A . n A 1 40 THR 40 260 260 THR THR A . n A 1 41 CYS 41 261 261 CYS CYS A . n A 1 42 VAL 42 262 262 VAL VAL A . n A 1 43 VAL 43 263 263 VAL VAL A . n A 1 44 VAL 44 264 264 VAL VAL A . n A 1 45 ASP 45 265 265 ASP ASP A . n A 1 46 VAL 46 266 266 VAL VAL A . n A 1 47 SER 47 267 267 SER SER A . n A 1 48 HIS 48 268 268 HIS HIS A . n A 1 49 GLU 49 269 269 GLU GLU A . n A 1 50 ASP 50 270 270 ASP ASP A . n A 1 51 PRO 51 271 271 PRO PRO A . n A 1 52 GLU 52 272 272 GLU GLU A . n A 1 53 VAL 53 273 273 VAL VAL A . n A 1 54 LYS 54 274 274 LYS LYS A . n A 1 55 PHE 55 275 275 PHE PHE A . n A 1 56 ASN 56 276 276 ASN ASN A . n A 1 57 TRP 57 277 277 TRP TRP A . n A 1 58 TYR 58 278 278 TYR TYR A . n A 1 59 VAL 59 279 279 VAL VAL A . n A 1 60 ASP 60 280 280 ASP ASP A . n A 1 61 GLY 61 281 281 GLY GLY A . n A 1 62 VAL 62 282 282 VAL VAL A . n A 1 63 GLU 63 283 283 GLU GLU A . n A 1 64 VAL 64 284 284 VAL VAL A . n A 1 65 HIS 65 285 285 HIS HIS A . n A 1 66 ASN 66 286 286 ASN ASN A . n A 1 67 ALA 67 287 287 ALA ALA A . n A 1 68 LYS 68 288 288 LYS LYS A . n A 1 69 THR 69 289 289 THR THR A . n A 1 70 LYS 70 290 290 LYS LYS A . n A 1 71 PRO 71 291 291 PRO PRO A . n A 1 72 ARG 72 292 292 ARG ARG A . n A 1 73 GLU 73 293 293 GLU GLU A . n A 1 74 GLU 74 294 294 GLU GLU A . n A 1 75 GLN 75 295 295 GLN GLN A . n A 1 76 TYR 76 296 296 TYR TYR A . n A 1 77 ASN 77 297 297 ASN ASN A . n A 1 78 SER 78 298 298 SER SER A . n A 1 79 THR 79 299 299 THR THR A . n A 1 80 TYR 80 300 300 TYR TYR A . n A 1 81 ARG 81 301 301 ARG ARG A . n A 1 82 VAL 82 302 302 VAL VAL A . n A 1 83 VAL 83 303 303 VAL VAL A . n A 1 84 SER 84 304 304 SER SER A . n A 1 85 VAL 85 305 305 VAL VAL A . n A 1 86 LEU 86 306 306 LEU LEU A . n A 1 87 THR 87 307 307 THR THR A . n A 1 88 VAL 88 308 308 VAL VAL A . n A 1 89 LEU 89 309 309 LEU LEU A . n A 1 90 HIS 90 310 310 HIS HIS A . n A 1 91 GLN 91 311 311 GLN GLN A . n A 1 92 ASP 92 312 312 ASP ASP A . n A 1 93 TRP 93 313 313 TRP TRP A . n A 1 94 LEU 94 314 314 LEU LEU A . n A 1 95 ASN 95 315 315 ASN ASN A . n A 1 96 GLY 96 316 316 GLY GLY A . n A 1 97 LYS 97 317 317 LYS LYS A . n A 1 98 GLU 98 318 318 GLU GLU A . n A 1 99 TYR 99 319 319 TYR TYR A . n A 1 100 LYS 100 320 320 LYS LYS A . n A 1 101 CYS 101 321 321 CYS CYS A . n A 1 102 LYS 102 322 322 LYS LYS A . n A 1 103 VAL 103 323 323 VAL VAL A . n A 1 104 SER 104 324 324 SER SER A . n A 1 105 ASN 105 325 325 ASN ASN A . n A 1 106 LYS 106 326 326 LYS LYS A . n A 1 107 ALA 107 327 327 ALA ALA A . n A 1 108 LEU 108 328 328 LEU LEU A . n A 1 109 PRO 109 329 329 PRO PRO A . n A 1 110 ALA 110 330 330 ALA ALA A . n A 1 111 PRO 111 331 331 PRO PRO A . n A 1 112 ILE 112 332 332 ILE ILE A . n A 1 113 GLU 113 333 333 GLU GLU A . n A 1 114 LYS 114 334 334 LYS LYS A . n A 1 115 THR 115 335 335 THR THR A . n A 1 116 ILE 116 336 336 ILE ILE A . n A 1 117 SER 117 337 337 SER SER A . n A 1 118 LYS 118 338 338 LYS LYS A . n A 1 119 ALA 119 339 339 ALA ALA A . n A 1 120 LYS 120 340 340 LYS LYS A . n A 1 121 GLY 121 341 341 GLY GLY A . n A 1 122 GLN 122 342 342 GLN GLN A . n A 1 123 PRO 123 343 343 PRO PRO A . n A 1 124 ARG 124 344 344 ARG ARG A . n A 1 125 GLU 125 345 345 GLU GLU A . n A 1 126 PRO 126 346 346 PRO PRO A . n A 1 127 GLN 127 347 347 GLN GLN A . n A 1 128 VAL 128 348 348 VAL VAL A . n A 1 129 TYR 129 349 349 TYR TYR A . n A 1 130 THR 130 350 350 THR THR A . n A 1 131 LEU 131 351 351 LEU LEU A . n A 1 132 PRO 132 352 352 PRO PRO A . n A 1 133 PRO 133 353 353 PRO PRO A . n A 1 134 SER 134 354 354 SER SER A . n A 1 135 ARG 135 355 355 ARG ARG A . n A 1 136 GLU 136 356 356 GLU GLU A . n A 1 137 GLU 137 357 357 GLU GLU A . n A 1 138 MET 138 358 358 MET MET A . n A 1 139 THR 139 359 359 THR THR A . n A 1 140 LYS 140 360 360 LYS LYS A . n A 1 141 ASN 141 361 361 ASN ASN A . n A 1 142 GLN 142 362 362 GLN GLN A . n A 1 143 VAL 143 363 363 VAL VAL A . n A 1 144 SER 144 364 364 SER SER A . n A 1 145 LEU 145 365 365 LEU LEU A . n A 1 146 THR 146 366 366 THR THR A . n A 1 147 CYS 147 367 367 CYS CYS A . n A 1 148 VAL 148 368 368 VAL VAL A . n A 1 149 VAL 149 369 369 VAL VAL A . n A 1 150 LYS 150 370 370 LYS LYS A . n A 1 151 GLY 151 371 371 GLY GLY A . n A 1 152 PHE 152 372 372 PHE PHE A . n A 1 153 TYR 153 373 373 TYR TYR A . n A 1 154 PRO 154 374 374 PRO PRO A . n A 1 155 SER 155 375 375 SER SER A . n A 1 156 ASP 156 376 376 ASP ASP A . n A 1 157 ILE 157 377 377 ILE ILE A . n A 1 158 ALA 158 378 378 ALA ALA A . n A 1 159 VAL 159 379 379 VAL VAL A . n A 1 160 GLU 160 380 380 GLU GLU A . n A 1 161 TRP 161 381 381 TRP TRP A . n A 1 162 GLU 162 382 382 GLU GLU A . n A 1 163 SER 163 383 383 SER SER A . n A 1 164 ASN 164 384 384 ASN ASN A . n A 1 165 GLY 165 385 385 GLY GLY A . n A 1 166 GLN 166 386 386 GLN GLN A . n A 1 167 PRO 167 387 387 PRO PRO A . n A 1 168 GLU 168 388 388 GLU GLU A . n A 1 169 ASN 169 389 389 ASN ASN A . n A 1 170 ASN 170 390 390 ASN ASN A . n A 1 171 TYR 171 391 391 TYR TYR A . n A 1 172 LYS 172 392 392 LYS LYS A . n A 1 173 THR 173 393 393 THR THR A . n A 1 174 THR 174 394 394 THR THR A . n A 1 175 PRO 175 395 395 PRO PRO A . n A 1 176 PRO 176 396 396 PRO PRO A . n A 1 177 VAL 177 397 397 VAL VAL A . n A 1 178 LEU 178 398 398 LEU LEU A . n A 1 179 ASP 179 399 399 ASP ASP A . n A 1 180 SER 180 400 400 SER SER A . n A 1 181 ASP 181 401 401 ASP ASP A . n A 1 182 GLY 182 402 402 GLY GLY A . n A 1 183 SER 183 403 403 SER SER A . n A 1 184 PHE 184 404 404 PHE PHE A . n A 1 185 PHE 185 405 405 PHE PHE A . n A 1 186 LEU 186 406 406 LEU LEU A . n A 1 187 ALA 187 407 407 ALA ALA A . n A 1 188 SER 188 408 408 SER SER A . n A 1 189 LYS 189 409 409 LYS LYS A . n A 1 190 LEU 190 410 410 LEU LEU A . n A 1 191 THR 191 411 411 THR THR A . n A 1 192 VAL 192 412 412 VAL VAL A . n A 1 193 ASP 193 413 413 ASP ASP A . n A 1 194 LYS 194 414 414 LYS LYS A . n A 1 195 SER 195 415 415 SER SER A . n A 1 196 ARG 196 416 416 ARG ARG A . n A 1 197 TRP 197 417 417 TRP TRP A . n A 1 198 GLN 198 418 418 GLN GLN A . n A 1 199 GLN 199 419 419 GLN GLN A . n A 1 200 GLY 200 420 420 GLY GLY A . n A 1 201 ASN 201 421 421 ASN ASN A . n A 1 202 VAL 202 422 422 VAL VAL A . n A 1 203 PHE 203 423 423 PHE PHE A . n A 1 204 SER 204 424 424 SER SER A . n A 1 205 CYS 205 425 425 CYS CYS A . n A 1 206 SER 206 426 426 SER SER A . n A 1 207 VAL 207 427 427 VAL VAL A . n A 1 208 MET 208 428 428 MET MET A . n A 1 209 HIS 209 429 429 HIS HIS A . n A 1 210 GLU 210 430 430 GLU GLU A . n A 1 211 ALA 211 431 431 ALA ALA A . n A 1 212 LEU 212 432 432 LEU LEU A . n A 1 213 HIS 213 433 433 HIS HIS A . n A 1 214 ASN 214 434 434 ASN ASN A . n A 1 215 HIS 215 435 435 HIS HIS A . n A 1 216 TYR 216 436 436 TYR TYR A . n A 1 217 THR 217 437 437 THR THR A . n A 1 218 GLN 218 438 438 GLN GLN A . n A 1 219 LYS 219 439 439 LYS LYS A . n A 1 220 SER 220 440 440 SER SER A . n A 1 221 LEU 221 441 441 LEU LEU A . n A 1 222 SER 222 442 442 SER SER A . n A 1 223 LEU 223 443 443 LEU LEU A . n A 1 224 SER 224 444 ? ? ? A . n A 1 225 PRO 225 445 ? ? ? A . n A 1 226 GLY 226 446 ? ? ? A . n A 1 227 LYS 227 447 ? ? ? A . n B 2 1 HIS 1 208 ? ? ? B . n B 2 2 HIS 2 209 ? ? ? B . n B 2 3 HIS 3 210 ? ? ? B . n B 2 4 HIS 4 211 ? ? ? B . n B 2 5 HIS 5 212 ? ? ? B . n B 2 6 HIS 6 213 ? ? ? B . n B 2 7 HIS 7 214 ? ? ? B . n B 2 8 HIS 8 215 ? ? ? B . n B 2 9 SER 9 216 ? ? ? B . n B 2 10 GLY 10 217 ? ? ? B . n B 2 11 SER 11 218 ? ? ? B . n B 2 12 GLY 12 219 ? ? ? B . n B 2 13 SER 13 220 ? ? ? B . n B 2 14 ASP 14 221 ? ? ? B . n B 2 15 LYS 15 222 ? ? ? B . n B 2 16 THR 16 223 ? ? ? B . n B 2 17 HIS 17 224 ? ? ? B . n B 2 18 THR 18 225 ? ? ? B . n B 2 19 CYS 19 226 ? ? ? B . n B 2 20 PRO 20 227 ? ? ? B . n B 2 21 PRO 21 228 ? ? ? B . n B 2 22 CYS 22 229 ? ? ? B . n B 2 23 PRO 23 230 ? ? ? B . n B 2 24 ALA 24 231 ? ? ? B . n B 2 25 PRO 25 232 ? ? ? B . n B 2 26 GLU 26 233 ? ? ? B . n B 2 27 LEU 27 234 ? ? ? B . n B 2 28 LEU 28 235 ? ? ? B . n B 2 29 GLY 29 236 ? ? ? B . n B 2 30 GLY 30 237 237 GLY GLY B . n B 2 31 PRO 31 238 238 PRO PRO B . n B 2 32 SER 32 239 239 SER SER B . n B 2 33 VAL 33 240 240 VAL VAL B . n B 2 34 PHE 34 241 241 PHE PHE B . n B 2 35 LEU 35 242 242 LEU LEU B . n B 2 36 PHE 36 243 243 PHE PHE B . n B 2 37 PRO 37 244 244 PRO PRO B . n B 2 38 PRO 38 245 245 PRO PRO B . n B 2 39 LYS 39 246 246 LYS LYS B . n B 2 40 PRO 40 247 247 PRO PRO B . n B 2 41 LYS 41 248 248 LYS LYS B . n B 2 42 ASP 42 249 249 ASP ASP B . n B 2 43 THR 43 250 250 THR THR B . n B 2 44 LEU 44 251 251 LEU LEU B . n B 2 45 GLU 45 252 252 GLU GLU B . n B 2 46 ALA 46 253 253 ALA ALA B . n B 2 47 SER 47 254 254 SER SER B . n B 2 48 ARG 48 255 255 ARG ARG B . n B 2 49 THR 49 256 256 THR THR B . n B 2 50 PRO 50 257 257 PRO PRO B . n B 2 51 GLU 51 258 258 GLU GLU B . n B 2 52 VAL 52 259 259 VAL VAL B . n B 2 53 THR 53 260 260 THR THR B . n B 2 54 CYS 54 261 261 CYS CYS B . n B 2 55 VAL 55 262 262 VAL VAL B . n B 2 56 VAL 56 263 263 VAL VAL B . n B 2 57 VAL 57 264 264 VAL VAL B . n B 2 58 ASP 58 265 265 ASP ASP B . n B 2 59 VAL 59 266 266 VAL VAL B . n B 2 60 SER 60 267 267 SER SER B . n B 2 61 HIS 61 268 268 HIS HIS B . n B 2 62 GLU 62 269 269 GLU GLU B . n B 2 63 ASP 63 270 270 ASP ASP B . n B 2 64 PRO 64 271 271 PRO PRO B . n B 2 65 GLU 65 272 272 GLU GLU B . n B 2 66 VAL 66 273 273 VAL VAL B . n B 2 67 LYS 67 274 274 LYS LYS B . n B 2 68 PHE 68 275 275 PHE PHE B . n B 2 69 ASN 69 276 276 ASN ASN B . n B 2 70 TRP 70 277 277 TRP TRP B . n B 2 71 TYR 71 278 278 TYR TYR B . n B 2 72 VAL 72 279 279 VAL VAL B . n B 2 73 ASP 73 280 280 ASP ASP B . n B 2 74 GLY 74 281 281 GLY GLY B . n B 2 75 VAL 75 282 282 VAL VAL B . n B 2 76 GLU 76 283 283 GLU GLU B . n B 2 77 VAL 77 284 284 VAL VAL B . n B 2 78 HIS 78 285 285 HIS HIS B . n B 2 79 ASN 79 286 286 ASN ASN B . n B 2 80 ALA 80 287 287 ALA ALA B . n B 2 81 LYS 81 288 288 LYS LYS B . n B 2 82 THR 82 289 289 THR THR B . n B 2 83 LYS 83 290 290 LYS LYS B . n B 2 84 PRO 84 291 291 PRO PRO B . n B 2 85 ARG 85 292 292 ARG ARG B . n B 2 86 GLU 86 293 293 GLU GLU B . n B 2 87 GLU 87 294 294 GLU GLU B . n B 2 88 GLN 88 295 295 GLN GLN B . n B 2 89 TYR 89 296 296 TYR TYR B . n B 2 90 ASN 90 297 297 ASN ASN B . n B 2 91 SER 91 298 298 SER SER B . n B 2 92 THR 92 299 299 THR THR B . n B 2 93 TYR 93 300 300 TYR TYR B . n B 2 94 ARG 94 301 301 ARG ARG B . n B 2 95 VAL 95 302 302 VAL VAL B . n B 2 96 VAL 96 303 303 VAL VAL B . n B 2 97 SER 97 304 304 SER SER B . n B 2 98 VAL 98 305 305 VAL VAL B . n B 2 99 LEU 99 306 306 LEU LEU B . n B 2 100 THR 100 307 307 THR THR B . n B 2 101 VAL 101 308 308 VAL VAL B . n B 2 102 LEU 102 309 309 LEU LEU B . n B 2 103 HIS 103 310 310 HIS HIS B . n B 2 104 GLN 104 311 311 GLN GLN B . n B 2 105 ASP 105 312 312 ASP ASP B . n B 2 106 TRP 106 313 313 TRP TRP B . n B 2 107 LEU 107 314 314 LEU LEU B . n B 2 108 ASN 108 315 315 ASN ASN B . n B 2 109 GLY 109 316 316 GLY GLY B . n B 2 110 LYS 110 317 317 LYS LYS B . n B 2 111 GLU 111 318 318 GLU GLU B . n B 2 112 TYR 112 319 319 TYR TYR B . n B 2 113 LYS 113 320 320 LYS LYS B . n B 2 114 CYS 114 321 321 CYS CYS B . n B 2 115 LYS 115 322 322 LYS LYS B . n B 2 116 VAL 116 323 323 VAL VAL B . n B 2 117 SER 117 324 324 SER SER B . n B 2 118 ASN 118 325 325 ASN ASN B . n B 2 119 LYS 119 326 326 LYS LYS B . n B 2 120 ALA 120 327 327 ALA ALA B . n B 2 121 LEU 121 328 328 LEU LEU B . n B 2 122 PRO 122 329 329 PRO PRO B . n B 2 123 ALA 123 330 330 ALA ALA B . n B 2 124 PRO 124 331 331 PRO PRO B . n B 2 125 ILE 125 332 332 ILE ILE B . n B 2 126 GLU 126 333 333 GLU GLU B . n B 2 127 LYS 127 334 334 LYS LYS B . n B 2 128 THR 128 335 335 THR THR B . n B 2 129 ILE 129 336 336 ILE ILE B . n B 2 130 SER 130 337 337 SER SER B . n B 2 131 LYS 131 338 338 LYS LYS B . n B 2 132 ALA 132 339 339 ALA ALA B . n B 2 133 LYS 133 340 340 LYS LYS B . n B 2 134 GLY 134 341 341 GLY GLY B . n B 2 135 GLN 135 342 342 GLN GLN B . n B 2 136 PRO 136 343 343 PRO PRO B . n B 2 137 ARG 137 344 344 ARG ARG B . n B 2 138 GLU 138 345 345 GLU GLU B . n B 2 139 PRO 139 346 346 PRO PRO B . n B 2 140 GLN 140 347 347 GLN GLN B . n B 2 141 VAL 141 348 348 VAL VAL B . n B 2 142 TYR 142 349 349 TYR TYR B . n B 2 143 THR 143 350 350 THR THR B . n B 2 144 LEU 144 351 351 LEU LEU B . n B 2 145 PRO 145 352 352 PRO PRO B . n B 2 146 PRO 146 353 353 PRO PRO B . n B 2 147 SER 147 354 354 SER SER B . n B 2 148 ARG 148 355 355 ARG ARG B . n B 2 149 GLU 149 356 356 GLU GLU B . n B 2 150 GLU 150 357 357 GLU GLU B . n B 2 151 MET 151 358 358 MET MET B . n B 2 152 THR 152 359 359 THR THR B . n B 2 153 LYS 153 360 360 LYS LYS B . n B 2 154 ASN 154 361 361 ASN ASN B . n B 2 155 GLN 155 362 362 GLN GLN B . n B 2 156 VAL 156 363 363 VAL VAL B . n B 2 157 SER 157 364 364 SER SER B . n B 2 158 LEU 158 365 365 LEU LEU B . n B 2 159 VAL 159 366 366 VAL VAL B . n B 2 160 CYS 160 367 367 CYS CYS B . n B 2 161 LEU 161 368 368 LEU LEU B . n B 2 162 VAL 162 369 369 VAL VAL B . n B 2 163 LYS 163 370 370 LYS LYS B . n B 2 164 GLY 164 371 371 GLY GLY B . n B 2 165 PHE 165 372 372 PHE PHE B . n B 2 166 TYR 166 373 373 TYR TYR B . n B 2 167 PRO 167 374 374 PRO PRO B . n B 2 168 SER 168 375 375 SER SER B . n B 2 169 ASP 169 376 376 ASP ASP B . n B 2 170 ILE 170 377 377 ILE ILE B . n B 2 171 ALA 171 378 378 ALA ALA B . n B 2 172 VAL 172 379 379 VAL VAL B . n B 2 173 GLU 173 380 380 GLU GLU B . n B 2 174 TRP 174 381 381 TRP TRP B . n B 2 175 GLU 175 382 382 GLU GLU B . n B 2 176 SER 176 383 383 SER SER B . n B 2 177 ASN 177 384 384 ASN ASN B . n B 2 178 GLY 178 385 385 GLY GLY B . n B 2 179 GLN 179 386 386 GLN GLN B . n B 2 180 PRO 180 387 387 PRO PRO B . n B 2 181 GLU 181 388 388 GLU GLU B . n B 2 182 ASN 182 389 389 ASN ASN B . n B 2 183 ASN 183 390 390 ASN ASN B . n B 2 184 TYR 184 391 391 TYR TYR B . n B 2 185 LYS 185 392 392 LYS LYS B . n B 2 186 THR 186 393 393 THR THR B . n B 2 187 THR 187 394 394 THR THR B . n B 2 188 PRO 188 395 395 PRO PRO B . n B 2 189 PRO 189 396 396 PRO PRO B . n B 2 190 VAL 190 397 397 VAL VAL B . n B 2 191 LEU 191 398 398 LEU LEU B . n B 2 192 ASP 192 399 399 ASP ASP B . n B 2 193 SER 193 400 400 SER SER B . n B 2 194 ASP 194 401 401 ASP ASP B . n B 2 195 GLY 195 402 402 GLY GLY B . n B 2 196 SER 196 403 403 SER SER B . n B 2 197 PHE 197 404 404 PHE PHE B . n B 2 198 PHE 198 405 405 PHE PHE B . n B 2 199 LEU 199 406 406 LEU LEU B . n B 2 200 TYR 200 407 407 TYR TYR B . n B 2 201 SER 201 408 408 SER SER B . n B 2 202 PHE 202 409 409 PHE PHE B . n B 2 203 LEU 203 410 410 LEU LEU B . n B 2 204 THR 204 411 411 THR THR B . n B 2 205 VAL 205 412 412 VAL VAL B . n B 2 206 ASP 206 413 413 ASP ASP B . n B 2 207 LYS 207 414 414 LYS LYS B . n B 2 208 SER 208 415 415 SER SER B . n B 2 209 ARG 209 416 416 ARG ARG B . n B 2 210 TRP 210 417 417 TRP TRP B . n B 2 211 GLN 211 418 418 GLN GLN B . n B 2 212 GLN 212 419 419 GLN GLN B . n B 2 213 GLY 213 420 ? ? ? B . n B 2 214 ASN 214 421 421 ASN ASN B . n B 2 215 VAL 215 422 422 VAL VAL B . n B 2 216 PHE 216 423 423 PHE PHE B . n B 2 217 SER 217 424 424 SER SER B . n B 2 218 CYS 218 425 425 CYS CYS B . n B 2 219 SER 219 426 426 SER SER B . n B 2 220 VAL 220 427 427 VAL VAL B . n B 2 221 MET 221 428 428 MET MET B . n B 2 222 HIS 222 429 429 HIS HIS B . n B 2 223 GLU 223 430 430 GLU GLU B . n B 2 224 ALA 224 431 431 ALA ALA B . n B 2 225 LEU 225 432 432 LEU LEU B . n B 2 226 HIS 226 433 433 HIS HIS B . n B 2 227 ASN 227 434 434 ASN ASN B . n B 2 228 ALA 228 435 435 ALA ALA B . n B 2 229 TYR 229 436 436 TYR TYR B . n B 2 230 THR 230 437 437 THR THR B . n B 2 231 GLN 231 438 438 GLN GLN B . n B 2 232 LYS 232 439 439 LYS LYS B . n B 2 233 SER 233 440 440 SER SER B . n B 2 234 LEU 234 441 441 LEU LEU B . n B 2 235 SER 235 442 442 SER SER B . n B 2 236 LEU 236 443 443 LEU LEU B . n B 2 237 SER 237 444 ? ? ? B . n B 2 238 PRO 238 445 ? ? ? B . n B 2 239 GLY 239 446 ? ? ? B . n B 2 240 LYS 240 447 ? ? ? B . n C 3 1 ASP 1 1 1 ASP ASP C . n C 3 2 CYS 2 2 2 CYS CYS C . n C 3 3 ALA 3 3 3 ALA ALA C . n C 3 4 TRP 4 4 4 TRP TRP C . n C 3 5 HIS 5 5 5 HIS HIS C . n C 3 6 LEU 6 6 6 LEU LEU C . n C 3 7 GLY 7 7 7 GLY GLY C . n C 3 8 GLU 8 8 8 GLU GLU C . n C 3 9 LEU 9 9 9 LEU LEU C . n C 3 10 VAL 10 10 10 VAL VAL C . n C 3 11 TRP 11 11 11 TRP TRP C . n C 3 12 CYS 12 12 12 CYS CYS C . n C 3 13 THR 13 13 13 THR THR C . n D 1 1 ASP 1 221 ? ? ? D . n D 1 2 LYS 2 222 ? ? ? D . n D 1 3 THR 3 223 ? ? ? D . n D 1 4 HIS 4 224 ? ? ? D . n D 1 5 THR 5 225 ? ? ? D . n D 1 6 CYS 6 226 ? ? ? D . n D 1 7 PRO 7 227 ? ? ? D . n D 1 8 PRO 8 228 ? ? ? D . n D 1 9 CYS 9 229 ? ? ? D . n D 1 10 PRO 10 230 ? ? ? D . n D 1 11 ALA 11 231 ? ? ? D . n D 1 12 PRO 12 232 ? ? ? D . n D 1 13 GLU 13 233 ? ? ? D . n D 1 14 LEU 14 234 ? ? ? D . n D 1 15 LEU 15 235 ? ? ? D . n D 1 16 GLY 16 236 ? ? ? D . n D 1 17 GLY 17 237 237 GLY GLY D . n D 1 18 PRO 18 238 238 PRO PRO D . n D 1 19 SER 19 239 239 SER SER D . n D 1 20 VAL 20 240 240 VAL VAL D . n D 1 21 PHE 21 241 241 PHE PHE D . n D 1 22 LEU 22 242 242 LEU LEU D . n D 1 23 PHE 23 243 243 PHE PHE D . n D 1 24 PRO 24 244 244 PRO PRO D . n D 1 25 PRO 25 245 245 PRO PRO D . n D 1 26 LYS 26 246 246 LYS LYS D . n D 1 27 PRO 27 247 247 PRO PRO D . n D 1 28 LYS 28 248 248 LYS LYS D . n D 1 29 ASP 29 249 249 ASP ASP D . n D 1 30 THR 30 250 250 THR THR D . n D 1 31 LEU 31 251 251 LEU LEU D . n D 1 32 MET 32 252 252 MET MET D . n D 1 33 ILE 33 253 253 ILE ILE D . n D 1 34 SER 34 254 254 SER SER D . n D 1 35 ARG 35 255 255 ARG ARG D . n D 1 36 THR 36 256 256 THR THR D . n D 1 37 PRO 37 257 257 PRO PRO D . n D 1 38 GLU 38 258 258 GLU GLU D . n D 1 39 VAL 39 259 259 VAL VAL D . n D 1 40 THR 40 260 260 THR THR D . n D 1 41 CYS 41 261 261 CYS CYS D . n D 1 42 VAL 42 262 262 VAL VAL D . n D 1 43 VAL 43 263 263 VAL VAL D . n D 1 44 VAL 44 264 264 VAL VAL D . n D 1 45 ASP 45 265 265 ASP ASP D . n D 1 46 VAL 46 266 266 VAL VAL D . n D 1 47 SER 47 267 267 SER SER D . n D 1 48 HIS 48 268 268 HIS HIS D . n D 1 49 GLU 49 269 269 GLU GLU D . n D 1 50 ASP 50 270 270 ASP ASP D . n D 1 51 PRO 51 271 271 PRO PRO D . n D 1 52 GLU 52 272 272 GLU GLU D . n D 1 53 VAL 53 273 273 VAL VAL D . n D 1 54 LYS 54 274 274 LYS LYS D . n D 1 55 PHE 55 275 275 PHE PHE D . n D 1 56 ASN 56 276 276 ASN ASN D . n D 1 57 TRP 57 277 277 TRP TRP D . n D 1 58 TYR 58 278 278 TYR TYR D . n D 1 59 VAL 59 279 279 VAL VAL D . n D 1 60 ASP 60 280 280 ASP ASP D . n D 1 61 GLY 61 281 281 GLY GLY D . n D 1 62 VAL 62 282 282 VAL VAL D . n D 1 63 GLU 63 283 283 GLU GLU D . n D 1 64 VAL 64 284 284 VAL VAL D . n D 1 65 HIS 65 285 285 HIS HIS D . n D 1 66 ASN 66 286 286 ASN ASN D . n D 1 67 ALA 67 287 287 ALA ALA D . n D 1 68 LYS 68 288 288 LYS LYS D . n D 1 69 THR 69 289 289 THR THR D . n D 1 70 LYS 70 290 290 LYS LYS D . n D 1 71 PRO 71 291 291 PRO PRO D . n D 1 72 ARG 72 292 292 ARG ARG D . n D 1 73 GLU 73 293 293 GLU GLU D . n D 1 74 GLU 74 294 294 GLU GLU D . n D 1 75 GLN 75 295 295 GLN GLN D . n D 1 76 TYR 76 296 296 TYR TYR D . n D 1 77 ASN 77 297 297 ASN ASN D . n D 1 78 SER 78 298 298 SER SER D . n D 1 79 THR 79 299 299 THR THR D . n D 1 80 TYR 80 300 300 TYR TYR D . n D 1 81 ARG 81 301 301 ARG ARG D . n D 1 82 VAL 82 302 302 VAL VAL D . n D 1 83 VAL 83 303 303 VAL VAL D . n D 1 84 SER 84 304 304 SER SER D . n D 1 85 VAL 85 305 305 VAL VAL D . n D 1 86 LEU 86 306 306 LEU LEU D . n D 1 87 THR 87 307 307 THR THR D . n D 1 88 VAL 88 308 308 VAL VAL D . n D 1 89 LEU 89 309 309 LEU LEU D . n D 1 90 HIS 90 310 310 HIS HIS D . n D 1 91 GLN 91 311 311 GLN GLN D . n D 1 92 ASP 92 312 312 ASP ASP D . n D 1 93 TRP 93 313 313 TRP TRP D . n D 1 94 LEU 94 314 314 LEU LEU D . n D 1 95 ASN 95 315 315 ASN ASN D . n D 1 96 GLY 96 316 316 GLY GLY D . n D 1 97 LYS 97 317 317 LYS LYS D . n D 1 98 GLU 98 318 318 GLU GLU D . n D 1 99 TYR 99 319 319 TYR TYR D . n D 1 100 LYS 100 320 320 LYS LYS D . n D 1 101 CYS 101 321 321 CYS CYS D . n D 1 102 LYS 102 322 322 LYS LYS D . n D 1 103 VAL 103 323 323 VAL VAL D . n D 1 104 SER 104 324 324 SER SER D . n D 1 105 ASN 105 325 325 ASN ASN D . n D 1 106 LYS 106 326 326 LYS LYS D . n D 1 107 ALA 107 327 327 ALA ALA D . n D 1 108 LEU 108 328 328 LEU LEU D . n D 1 109 PRO 109 329 329 PRO PRO D . n D 1 110 ALA 110 330 330 ALA ALA D . n D 1 111 PRO 111 331 331 PRO PRO D . n D 1 112 ILE 112 332 332 ILE ILE D . n D 1 113 GLU 113 333 333 GLU GLU D . n D 1 114 LYS 114 334 334 LYS LYS D . n D 1 115 THR 115 335 335 THR THR D . n D 1 116 ILE 116 336 336 ILE ILE D . n D 1 117 SER 117 337 337 SER SER D . n D 1 118 LYS 118 338 338 LYS LYS D . n D 1 119 ALA 119 339 339 ALA ALA D . n D 1 120 LYS 120 340 340 LYS LYS D . n D 1 121 GLY 121 341 341 GLY GLY D . n D 1 122 GLN 122 342 342 GLN GLN D . n D 1 123 PRO 123 343 343 PRO PRO D . n D 1 124 ARG 124 344 344 ARG ARG D . n D 1 125 GLU 125 345 345 GLU GLU D . n D 1 126 PRO 126 346 346 PRO PRO D . n D 1 127 GLN 127 347 347 GLN GLN D . n D 1 128 VAL 128 348 348 VAL VAL D . n D 1 129 TYR 129 349 349 TYR TYR D . n D 1 130 THR 130 350 350 THR THR D . n D 1 131 LEU 131 351 351 LEU LEU D . n D 1 132 PRO 132 352 352 PRO PRO D . n D 1 133 PRO 133 353 353 PRO PRO D . n D 1 134 SER 134 354 354 SER SER D . n D 1 135 ARG 135 355 355 ARG ARG D . n D 1 136 GLU 136 356 356 GLU GLU D . n D 1 137 GLU 137 357 357 GLU GLU D . n D 1 138 MET 138 358 358 MET MET D . n D 1 139 THR 139 359 359 THR THR D . n D 1 140 LYS 140 360 360 LYS LYS D . n D 1 141 ASN 141 361 361 ASN ASN D . n D 1 142 GLN 142 362 362 GLN GLN D . n D 1 143 VAL 143 363 363 VAL VAL D . n D 1 144 SER 144 364 364 SER SER D . n D 1 145 LEU 145 365 365 LEU LEU D . n D 1 146 THR 146 366 366 THR THR D . n D 1 147 CYS 147 367 367 CYS CYS D . n D 1 148 VAL 148 368 368 VAL VAL D . n D 1 149 VAL 149 369 369 VAL VAL D . n D 1 150 LYS 150 370 370 LYS LYS D . n D 1 151 GLY 151 371 371 GLY GLY D . n D 1 152 PHE 152 372 372 PHE PHE D . n D 1 153 TYR 153 373 373 TYR TYR D . n D 1 154 PRO 154 374 374 PRO PRO D . n D 1 155 SER 155 375 375 SER SER D . n D 1 156 ASP 156 376 376 ASP ASP D . n D 1 157 ILE 157 377 377 ILE ILE D . n D 1 158 ALA 158 378 378 ALA ALA D . n D 1 159 VAL 159 379 379 VAL VAL D . n D 1 160 GLU 160 380 380 GLU GLU D . n D 1 161 TRP 161 381 381 TRP TRP D . n D 1 162 GLU 162 382 382 GLU GLU D . n D 1 163 SER 163 383 383 SER SER D . n D 1 164 ASN 164 384 384 ASN ASN D . n D 1 165 GLY 165 385 385 GLY GLY D . n D 1 166 GLN 166 386 386 GLN GLN D . n D 1 167 PRO 167 387 387 PRO PRO D . n D 1 168 GLU 168 388 388 GLU GLU D . n D 1 169 ASN 169 389 389 ASN ASN D . n D 1 170 ASN 170 390 390 ASN ASN D . n D 1 171 TYR 171 391 391 TYR TYR D . n D 1 172 LYS 172 392 392 LYS LYS D . n D 1 173 THR 173 393 393 THR THR D . n D 1 174 THR 174 394 394 THR THR D . n D 1 175 PRO 175 395 395 PRO PRO D . n D 1 176 PRO 176 396 396 PRO PRO D . n D 1 177 VAL 177 397 397 VAL VAL D . n D 1 178 LEU 178 398 398 LEU LEU D . n D 1 179 ASP 179 399 399 ASP ASP D . n D 1 180 SER 180 400 400 SER SER D . n D 1 181 ASP 181 401 401 ASP ASP D . n D 1 182 GLY 182 402 402 GLY GLY D . n D 1 183 SER 183 403 403 SER SER D . n D 1 184 PHE 184 404 404 PHE PHE D . n D 1 185 PHE 185 405 405 PHE PHE D . n D 1 186 LEU 186 406 406 LEU LEU D . n D 1 187 ALA 187 407 407 ALA ALA D . n D 1 188 SER 188 408 408 SER SER D . n D 1 189 LYS 189 409 409 LYS LYS D . n D 1 190 LEU 190 410 410 LEU LEU D . n D 1 191 THR 191 411 411 THR THR D . n D 1 192 VAL 192 412 412 VAL VAL D . n D 1 193 ASP 193 413 413 ASP ASP D . n D 1 194 LYS 194 414 414 LYS LYS D . n D 1 195 SER 195 415 415 SER SER D . n D 1 196 ARG 196 416 416 ARG ARG D . n D 1 197 TRP 197 417 417 TRP TRP D . n D 1 198 GLN 198 418 418 GLN GLN D . n D 1 199 GLN 199 419 419 GLN GLN D . n D 1 200 GLY 200 420 420 GLY GLY D . n D 1 201 ASN 201 421 421 ASN ASN D . n D 1 202 VAL 202 422 422 VAL VAL D . n D 1 203 PHE 203 423 423 PHE PHE D . n D 1 204 SER 204 424 424 SER SER D . n D 1 205 CYS 205 425 425 CYS CYS D . n D 1 206 SER 206 426 426 SER SER D . n D 1 207 VAL 207 427 427 VAL VAL D . n D 1 208 MET 208 428 428 MET MET D . n D 1 209 HIS 209 429 429 HIS HIS D . n D 1 210 GLU 210 430 430 GLU GLU D . n D 1 211 ALA 211 431 431 ALA ALA D . n D 1 212 LEU 212 432 432 LEU LEU D . n D 1 213 HIS 213 433 433 HIS HIS D . n D 1 214 ASN 214 434 434 ASN ASN D . n D 1 215 HIS 215 435 435 HIS HIS D . n D 1 216 TYR 216 436 436 TYR TYR D . n D 1 217 THR 217 437 437 THR THR D . n D 1 218 GLN 218 438 438 GLN GLN D . n D 1 219 LYS 219 439 439 LYS LYS D . n D 1 220 SER 220 440 440 SER SER D . n D 1 221 LEU 221 441 441 LEU LEU D . n D 1 222 SER 222 442 442 SER SER D . n D 1 223 LEU 223 443 443 LEU LEU D . n D 1 224 SER 224 444 ? ? ? D . n D 1 225 PRO 225 445 ? ? ? D . n D 1 226 GLY 226 446 ? ? ? D . n D 1 227 LYS 227 447 ? ? ? D . n E 2 1 HIS 1 208 ? ? ? E . n E 2 2 HIS 2 209 ? ? ? E . n E 2 3 HIS 3 210 ? ? ? E . n E 2 4 HIS 4 211 ? ? ? E . n E 2 5 HIS 5 212 ? ? ? E . n E 2 6 HIS 6 213 ? ? ? E . n E 2 7 HIS 7 214 ? ? ? E . n E 2 8 HIS 8 215 ? ? ? E . n E 2 9 SER 9 216 ? ? ? E . n E 2 10 GLY 10 217 ? ? ? E . n E 2 11 SER 11 218 ? ? ? E . n E 2 12 GLY 12 219 ? ? ? E . n E 2 13 SER 13 220 ? ? ? E . n E 2 14 ASP 14 221 ? ? ? E . n E 2 15 LYS 15 222 ? ? ? E . n E 2 16 THR 16 223 ? ? ? E . n E 2 17 HIS 17 224 ? ? ? E . n E 2 18 THR 18 225 ? ? ? E . n E 2 19 CYS 19 226 ? ? ? E . n E 2 20 PRO 20 227 ? ? ? E . n E 2 21 PRO 21 228 ? ? ? E . n E 2 22 CYS 22 229 ? ? ? E . n E 2 23 PRO 23 230 ? ? ? E . n E 2 24 ALA 24 231 ? ? ? E . n E 2 25 PRO 25 232 ? ? ? E . n E 2 26 GLU 26 233 ? ? ? E . n E 2 27 LEU 27 234 ? ? ? E . n E 2 28 LEU 28 235 ? ? ? E . n E 2 29 GLY 29 236 ? ? ? E . n E 2 30 GLY 30 237 237 GLY GLY E . n E 2 31 PRO 31 238 238 PRO PRO E . n E 2 32 SER 32 239 239 SER SER E . n E 2 33 VAL 33 240 240 VAL VAL E . n E 2 34 PHE 34 241 241 PHE PHE E . n E 2 35 LEU 35 242 242 LEU LEU E . n E 2 36 PHE 36 243 243 PHE PHE E . n E 2 37 PRO 37 244 244 PRO PRO E . n E 2 38 PRO 38 245 245 PRO PRO E . n E 2 39 LYS 39 246 246 LYS LYS E . n E 2 40 PRO 40 247 247 PRO PRO E . n E 2 41 LYS 41 248 248 LYS LYS E . n E 2 42 ASP 42 249 249 ASP ASP E . n E 2 43 THR 43 250 250 THR THR E . n E 2 44 LEU 44 251 251 LEU LEU E . n E 2 45 GLU 45 252 252 GLU GLU E . n E 2 46 ALA 46 253 253 ALA ALA E . n E 2 47 SER 47 254 254 SER SER E . n E 2 48 ARG 48 255 255 ARG ARG E . n E 2 49 THR 49 256 256 THR THR E . n E 2 50 PRO 50 257 257 PRO PRO E . n E 2 51 GLU 51 258 258 GLU GLU E . n E 2 52 VAL 52 259 259 VAL VAL E . n E 2 53 THR 53 260 260 THR THR E . n E 2 54 CYS 54 261 261 CYS CYS E . n E 2 55 VAL 55 262 262 VAL VAL E . n E 2 56 VAL 56 263 263 VAL VAL E . n E 2 57 VAL 57 264 264 VAL VAL E . n E 2 58 ASP 58 265 265 ASP ASP E . n E 2 59 VAL 59 266 266 VAL VAL E . n E 2 60 SER 60 267 267 SER SER E . n E 2 61 HIS 61 268 268 HIS HIS E . n E 2 62 GLU 62 269 269 GLU GLU E . n E 2 63 ASP 63 270 270 ASP ASP E . n E 2 64 PRO 64 271 271 PRO PRO E . n E 2 65 GLU 65 272 272 GLU GLU E . n E 2 66 VAL 66 273 273 VAL VAL E . n E 2 67 LYS 67 274 274 LYS LYS E . n E 2 68 PHE 68 275 275 PHE PHE E . n E 2 69 ASN 69 276 276 ASN ASN E . n E 2 70 TRP 70 277 277 TRP TRP E . n E 2 71 TYR 71 278 278 TYR TYR E . n E 2 72 VAL 72 279 279 VAL VAL E . n E 2 73 ASP 73 280 280 ASP ASP E . n E 2 74 GLY 74 281 281 GLY GLY E . n E 2 75 VAL 75 282 282 VAL VAL E . n E 2 76 GLU 76 283 283 GLU GLU E . n E 2 77 VAL 77 284 284 VAL VAL E . n E 2 78 HIS 78 285 285 HIS HIS E . n E 2 79 ASN 79 286 286 ASN ASN E . n E 2 80 ALA 80 287 287 ALA ALA E . n E 2 81 LYS 81 288 288 LYS LYS E . n E 2 82 THR 82 289 289 THR THR E . n E 2 83 LYS 83 290 290 LYS LYS E . n E 2 84 PRO 84 291 291 PRO PRO E . n E 2 85 ARG 85 292 292 ARG ARG E . n E 2 86 GLU 86 293 293 GLU GLU E . n E 2 87 GLU 87 294 294 GLU GLU E . n E 2 88 GLN 88 295 295 GLN GLN E . n E 2 89 TYR 89 296 296 TYR TYR E . n E 2 90 ASN 90 297 297 ASN ASN E . n E 2 91 SER 91 298 298 SER SER E . n E 2 92 THR 92 299 299 THR THR E . n E 2 93 TYR 93 300 300 TYR TYR E . n E 2 94 ARG 94 301 301 ARG ARG E . n E 2 95 VAL 95 302 302 VAL VAL E . n E 2 96 VAL 96 303 303 VAL VAL E . n E 2 97 SER 97 304 304 SER SER E . n E 2 98 VAL 98 305 305 VAL VAL E . n E 2 99 LEU 99 306 306 LEU LEU E . n E 2 100 THR 100 307 307 THR THR E . n E 2 101 VAL 101 308 308 VAL VAL E . n E 2 102 LEU 102 309 309 LEU LEU E . n E 2 103 HIS 103 310 310 HIS HIS E . n E 2 104 GLN 104 311 311 GLN GLN E . n E 2 105 ASP 105 312 312 ASP ASP E . n E 2 106 TRP 106 313 313 TRP TRP E . n E 2 107 LEU 107 314 314 LEU LEU E . n E 2 108 ASN 108 315 315 ASN ASN E . n E 2 109 GLY 109 316 316 GLY GLY E . n E 2 110 LYS 110 317 317 LYS LYS E . n E 2 111 GLU 111 318 318 GLU GLU E . n E 2 112 TYR 112 319 319 TYR TYR E . n E 2 113 LYS 113 320 320 LYS LYS E . n E 2 114 CYS 114 321 321 CYS CYS E . n E 2 115 LYS 115 322 322 LYS LYS E . n E 2 116 VAL 116 323 323 VAL VAL E . n E 2 117 SER 117 324 324 SER SER E . n E 2 118 ASN 118 325 325 ASN ASN E . n E 2 119 LYS 119 326 326 LYS LYS E . n E 2 120 ALA 120 327 327 ALA ALA E . n E 2 121 LEU 121 328 328 LEU LEU E . n E 2 122 PRO 122 329 329 PRO PRO E . n E 2 123 ALA 123 330 330 ALA ALA E . n E 2 124 PRO 124 331 331 PRO PRO E . n E 2 125 ILE 125 332 332 ILE ILE E . n E 2 126 GLU 126 333 333 GLU GLU E . n E 2 127 LYS 127 334 334 LYS LYS E . n E 2 128 THR 128 335 335 THR THR E . n E 2 129 ILE 129 336 336 ILE ILE E . n E 2 130 SER 130 337 337 SER SER E . n E 2 131 LYS 131 338 338 LYS LYS E . n E 2 132 ALA 132 339 339 ALA ALA E . n E 2 133 LYS 133 340 340 LYS LYS E . n E 2 134 GLY 134 341 341 GLY GLY E . n E 2 135 GLN 135 342 342 GLN GLN E . n E 2 136 PRO 136 343 343 PRO PRO E . n E 2 137 ARG 137 344 344 ARG ARG E . n E 2 138 GLU 138 345 345 GLU GLU E . n E 2 139 PRO 139 346 346 PRO PRO E . n E 2 140 GLN 140 347 347 GLN GLN E . n E 2 141 VAL 141 348 348 VAL VAL E . n E 2 142 TYR 142 349 349 TYR TYR E . n E 2 143 THR 143 350 350 THR THR E . n E 2 144 LEU 144 351 351 LEU LEU E . n E 2 145 PRO 145 352 352 PRO PRO E . n E 2 146 PRO 146 353 353 PRO PRO E . n E 2 147 SER 147 354 354 SER SER E . n E 2 148 ARG 148 355 355 ARG ARG E . n E 2 149 GLU 149 356 356 GLU GLU E . n E 2 150 GLU 150 357 357 GLU GLU E . n E 2 151 MET 151 358 358 MET MET E . n E 2 152 THR 152 359 359 THR THR E . n E 2 153 LYS 153 360 360 LYS LYS E . n E 2 154 ASN 154 361 361 ASN ASN E . n E 2 155 GLN 155 362 362 GLN GLN E . n E 2 156 VAL 156 363 363 VAL VAL E . n E 2 157 SER 157 364 364 SER SER E . n E 2 158 LEU 158 365 365 LEU LEU E . n E 2 159 VAL 159 366 366 VAL VAL E . n E 2 160 CYS 160 367 367 CYS CYS E . n E 2 161 LEU 161 368 368 LEU LEU E . n E 2 162 VAL 162 369 369 VAL VAL E . n E 2 163 LYS 163 370 370 LYS LYS E . n E 2 164 GLY 164 371 371 GLY GLY E . n E 2 165 PHE 165 372 372 PHE PHE E . n E 2 166 TYR 166 373 373 TYR TYR E . n E 2 167 PRO 167 374 374 PRO PRO E . n E 2 168 SER 168 375 375 SER SER E . n E 2 169 ASP 169 376 376 ASP ASP E . n E 2 170 ILE 170 377 377 ILE ILE E . n E 2 171 ALA 171 378 378 ALA ALA E . n E 2 172 VAL 172 379 379 VAL VAL E . n E 2 173 GLU 173 380 380 GLU GLU E . n E 2 174 TRP 174 381 381 TRP TRP E . n E 2 175 GLU 175 382 382 GLU GLU E . n E 2 176 SER 176 383 383 SER SER E . n E 2 177 ASN 177 384 384 ASN ASN E . n E 2 178 GLY 178 385 385 GLY GLY E . n E 2 179 GLN 179 386 386 GLN GLN E . n E 2 180 PRO 180 387 387 PRO PRO E . n E 2 181 GLU 181 388 388 GLU GLU E . n E 2 182 ASN 182 389 389 ASN ASN E . n E 2 183 ASN 183 390 390 ASN ASN E . n E 2 184 TYR 184 391 391 TYR TYR E . n E 2 185 LYS 185 392 392 LYS LYS E . n E 2 186 THR 186 393 393 THR THR E . n E 2 187 THR 187 394 394 THR THR E . n E 2 188 PRO 188 395 395 PRO PRO E . n E 2 189 PRO 189 396 396 PRO PRO E . n E 2 190 VAL 190 397 397 VAL VAL E . n E 2 191 LEU 191 398 398 LEU LEU E . n E 2 192 ASP 192 399 399 ASP ASP E . n E 2 193 SER 193 400 400 SER SER E . n E 2 194 ASP 194 401 401 ASP ASP E . n E 2 195 GLY 195 402 402 GLY GLY E . n E 2 196 SER 196 403 403 SER SER E . n E 2 197 PHE 197 404 404 PHE PHE E . n E 2 198 PHE 198 405 405 PHE PHE E . n E 2 199 LEU 199 406 406 LEU LEU E . n E 2 200 TYR 200 407 407 TYR TYR E . n E 2 201 SER 201 408 408 SER SER E . n E 2 202 PHE 202 409 409 PHE PHE E . n E 2 203 LEU 203 410 410 LEU LEU E . n E 2 204 THR 204 411 411 THR THR E . n E 2 205 VAL 205 412 412 VAL VAL E . n E 2 206 ASP 206 413 413 ASP ASP E . n E 2 207 LYS 207 414 414 LYS LYS E . n E 2 208 SER 208 415 415 SER SER E . n E 2 209 ARG 209 416 416 ARG ARG E . n E 2 210 TRP 210 417 417 TRP TRP E . n E 2 211 GLN 211 418 418 GLN GLN E . n E 2 212 GLN 212 419 419 GLN GLN E . n E 2 213 GLY 213 420 420 GLY GLY E . n E 2 214 ASN 214 421 421 ASN ASN E . n E 2 215 VAL 215 422 422 VAL VAL E . n E 2 216 PHE 216 423 423 PHE PHE E . n E 2 217 SER 217 424 424 SER SER E . n E 2 218 CYS 218 425 425 CYS CYS E . n E 2 219 SER 219 426 426 SER SER E . n E 2 220 VAL 220 427 427 VAL VAL E . n E 2 221 MET 221 428 428 MET MET E . n E 2 222 HIS 222 429 429 HIS HIS E . n E 2 223 GLU 223 430 430 GLU GLU E . n E 2 224 ALA 224 431 431 ALA ALA E . n E 2 225 LEU 225 432 432 LEU LEU E . n E 2 226 HIS 226 433 433 HIS HIS E . n E 2 227 ASN 227 434 434 ASN ASN E . n E 2 228 ALA 228 435 435 ALA ALA E . n E 2 229 TYR 229 436 436 TYR TYR E . n E 2 230 THR 230 437 437 THR THR E . n E 2 231 GLN 231 438 438 GLN GLN E . n E 2 232 LYS 232 439 439 LYS LYS E . n E 2 233 SER 233 440 440 SER SER E . n E 2 234 LEU 234 441 441 LEU LEU E . n E 2 235 SER 235 442 442 SER SER E . n E 2 236 LEU 236 443 443 LEU LEU E . n E 2 237 SER 237 444 ? ? ? E . n E 2 238 PRO 238 445 ? ? ? E . n E 2 239 GLY 239 446 ? ? ? E . n E 2 240 LYS 240 447 ? ? ? E . n F 3 1 ASP 1 1 1 ASP ASP F . n F 3 2 CYS 2 2 2 CYS CYS F . n F 3 3 ALA 3 3 3 ALA ALA F . n F 3 4 TRP 4 4 4 TRP TRP F . n F 3 5 HIS 5 5 5 HIS HIS F . n F 3 6 LEU 6 6 6 LEU LEU F . n F 3 7 GLY 7 7 7 GLY GLY F . n F 3 8 GLU 8 8 8 GLU GLU F . n F 3 9 LEU 9 9 9 LEU LEU F . n F 3 10 VAL 10 10 10 VAL VAL F . n F 3 11 TRP 11 11 11 TRP TRP F . n F 3 12 CYS 12 12 12 CYS CYS F . n F 3 13 THR 13 13 13 THR THR F . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code G 4 NAG 1 501 17 NAG NAG A . H 4 NAG 2 502 18 NAG NAG A . I 5 BMA 3 503 19 BMA BMA A . J 6 MAN 4 504 20 MAN MAN A . K 4 NAG 5 505 21 NAG NAG A . L 7 GAL 6 506 22 GAL GAL A . M 8 FUC 7 507 23 FUC FUC A . N 6 MAN 8 508 24 MAN MAN A . O 4 NAG 1 501 25 NAG NAG B . P 4 NAG 2 502 26 NAG NAG B . Q 5 BMA 3 503 27 BMA BMA B . R 6 MAN 4 504 28 MAN MAN B . S 4 NAG 5 505 29 NAG NAG B . T 7 GAL 6 506 30 GAL GAL B . U 6 MAN 7 507 31 MAN MAN B . V 8 FUC 8 508 32 FUC FUC B . W 4 NAG 1 501 1 NAG NAG D . X 4 NAG 2 502 2 NAG NAG D . Y 5 BMA 3 503 3 BMA BMA D . Z 6 MAN 4 504 4 MAN MAN D . AA 4 NAG 5 505 5 NAG NAG D . BA 7 GAL 6 506 6 GAL GAL D . CA 8 FUC 7 507 7 FUC FUC D . DA 6 MAN 8 508 8 MAN MAN D . EA 9 IOD 1 509 33 IOD IOD D . FA 4 NAG 1 501 9 NAG NAG E . GA 4 NAG 2 502 10 NAG NAG E . HA 5 BMA 3 503 11 BMA BMA E . IA 6 MAN 4 504 12 MAN MAN E . JA 4 NAG 5 505 13 NAG NAG E . KA 7 GAL 6 506 14 GAL GAL E . LA 6 MAN 7 507 15 MAN MAN E . MA 8 FUC 8 508 16 FUC FUC E . NA 10 HOH 1 601 29 HOH HOH A . NA 10 HOH 2 602 79 HOH HOH A . NA 10 HOH 3 603 109 HOH HOH A . NA 10 HOH 4 604 184 HOH HOH A . NA 10 HOH 5 605 170 HOH HOH A . NA 10 HOH 6 606 140 HOH HOH A . NA 10 HOH 7 607 98 HOH HOH A . NA 10 HOH 8 608 19 HOH HOH A . NA 10 HOH 9 609 54 HOH HOH A . NA 10 HOH 10 610 141 HOH HOH A . NA 10 HOH 11 611 9 HOH HOH A . NA 10 HOH 12 612 143 HOH HOH A . NA 10 HOH 13 613 10 HOH HOH A . NA 10 HOH 14 614 103 HOH HOH A . NA 10 HOH 15 615 15 HOH HOH A . NA 10 HOH 16 616 32 HOH HOH A . NA 10 HOH 17 617 149 HOH HOH A . NA 10 HOH 18 618 55 HOH HOH A . NA 10 HOH 19 619 164 HOH HOH A . NA 10 HOH 20 620 3 HOH HOH A . NA 10 HOH 21 621 74 HOH HOH A . NA 10 HOH 22 622 34 HOH HOH A . NA 10 HOH 23 623 47 HOH HOH A . NA 10 HOH 24 624 182 HOH HOH A . NA 10 HOH 25 625 46 HOH HOH A . NA 10 HOH 26 626 1 HOH HOH A . NA 10 HOH 27 627 70 HOH HOH A . NA 10 HOH 28 628 174 HOH HOH A . NA 10 HOH 29 629 6 HOH HOH A . NA 10 HOH 30 630 139 HOH HOH A . NA 10 HOH 31 631 56 HOH HOH A . NA 10 HOH 32 632 95 HOH HOH A . NA 10 HOH 33 633 181 HOH HOH A . NA 10 HOH 34 634 176 HOH HOH A . NA 10 HOH 35 635 124 HOH HOH A . NA 10 HOH 36 636 22 HOH HOH A . NA 10 HOH 37 637 35 HOH HOH A . NA 10 HOH 38 638 167 HOH HOH A . NA 10 HOH 39 639 2 HOH HOH A . NA 10 HOH 40 640 94 HOH HOH A . NA 10 HOH 41 641 81 HOH HOH A . NA 10 HOH 42 642 13 HOH HOH A . NA 10 HOH 43 643 172 HOH HOH A . NA 10 HOH 44 644 33 HOH HOH A . NA 10 HOH 45 645 162 HOH HOH A . NA 10 HOH 46 646 157 HOH HOH A . NA 10 HOH 47 647 148 HOH HOH A . NA 10 HOH 48 648 107 HOH HOH A . NA 10 HOH 49 649 48 HOH HOH A . NA 10 HOH 50 650 90 HOH HOH A . NA 10 HOH 51 651 92 HOH HOH A . NA 10 HOH 52 652 159 HOH HOH A . NA 10 HOH 53 653 50 HOH HOH A . NA 10 HOH 54 654 59 HOH HOH A . NA 10 HOH 55 655 146 HOH HOH A . NA 10 HOH 56 656 18 HOH HOH A . NA 10 HOH 57 657 16 HOH HOH A . NA 10 HOH 58 658 30 HOH HOH A . NA 10 HOH 59 659 187 HOH HOH A . NA 10 HOH 60 660 87 HOH HOH A . NA 10 HOH 61 661 153 HOH HOH A . NA 10 HOH 62 662 177 HOH HOH A . NA 10 HOH 63 663 65 HOH HOH A . NA 10 HOH 64 664 175 HOH HOH A . OA 10 HOH 1 601 64 HOH HOH B . OA 10 HOH 2 602 80 HOH HOH B . OA 10 HOH 3 603 11 HOH HOH B . OA 10 HOH 4 604 189 HOH HOH B . OA 10 HOH 5 605 168 HOH HOH B . OA 10 HOH 6 606 5 HOH HOH B . OA 10 HOH 7 607 39 HOH HOH B . OA 10 HOH 8 608 42 HOH HOH B . OA 10 HOH 9 609 112 HOH HOH B . OA 10 HOH 10 610 131 HOH HOH B . OA 10 HOH 11 611 136 HOH HOH B . OA 10 HOH 12 612 104 HOH HOH B . OA 10 HOH 13 613 17 HOH HOH B . OA 10 HOH 14 614 155 HOH HOH B . OA 10 HOH 15 615 108 HOH HOH B . OA 10 HOH 16 616 66 HOH HOH B . OA 10 HOH 17 617 129 HOH HOH B . OA 10 HOH 18 618 165 HOH HOH B . OA 10 HOH 19 619 67 HOH HOH B . OA 10 HOH 20 620 111 HOH HOH B . OA 10 HOH 21 621 14 HOH HOH B . OA 10 HOH 22 622 119 HOH HOH B . OA 10 HOH 23 623 105 HOH HOH B . OA 10 HOH 24 624 147 HOH HOH B . OA 10 HOH 25 625 178 HOH HOH B . PA 10 HOH 1 101 51 HOH HOH C . QA 10 HOH 1 601 53 HOH HOH D . QA 10 HOH 2 602 91 HOH HOH D . QA 10 HOH 3 603 134 HOH HOH D . QA 10 HOH 4 604 4 HOH HOH D . QA 10 HOH 5 605 41 HOH HOH D . QA 10 HOH 6 606 152 HOH HOH D . QA 10 HOH 7 607 144 HOH HOH D . QA 10 HOH 8 608 23 HOH HOH D . QA 10 HOH 9 609 61 HOH HOH D . QA 10 HOH 10 610 183 HOH HOH D . QA 10 HOH 11 611 123 HOH HOH D . QA 10 HOH 12 612 82 HOH HOH D . QA 10 HOH 13 613 137 HOH HOH D . QA 10 HOH 14 614 101 HOH HOH D . QA 10 HOH 15 615 127 HOH HOH D . QA 10 HOH 16 616 128 HOH HOH D . QA 10 HOH 17 617 113 HOH HOH D . QA 10 HOH 18 618 78 HOH HOH D . QA 10 HOH 19 619 28 HOH HOH D . QA 10 HOH 20 620 156 HOH HOH D . QA 10 HOH 21 621 100 HOH HOH D . QA 10 HOH 22 622 154 HOH HOH D . QA 10 HOH 23 623 38 HOH HOH D . QA 10 HOH 24 624 26 HOH HOH D . QA 10 HOH 25 625 27 HOH HOH D . QA 10 HOH 26 626 62 HOH HOH D . QA 10 HOH 27 627 118 HOH HOH D . QA 10 HOH 28 628 49 HOH HOH D . QA 10 HOH 29 629 24 HOH HOH D . QA 10 HOH 30 630 63 HOH HOH D . QA 10 HOH 31 631 21 HOH HOH D . QA 10 HOH 32 632 121 HOH HOH D . QA 10 HOH 33 633 7 HOH HOH D . QA 10 HOH 34 634 68 HOH HOH D . QA 10 HOH 35 635 58 HOH HOH D . QA 10 HOH 36 636 120 HOH HOH D . QA 10 HOH 37 637 83 HOH HOH D . QA 10 HOH 38 638 52 HOH HOH D . QA 10 HOH 39 639 125 HOH HOH D . QA 10 HOH 40 640 173 HOH HOH D . QA 10 HOH 41 641 179 HOH HOH D . QA 10 HOH 42 642 69 HOH HOH D . QA 10 HOH 43 643 57 HOH HOH D . QA 10 HOH 44 644 40 HOH HOH D . QA 10 HOH 45 645 8 HOH HOH D . QA 10 HOH 46 646 171 HOH HOH D . QA 10 HOH 47 647 88 HOH HOH D . QA 10 HOH 48 648 96 HOH HOH D . QA 10 HOH 49 649 130 HOH HOH D . QA 10 HOH 50 650 163 HOH HOH D . QA 10 HOH 51 651 60 HOH HOH D . QA 10 HOH 52 652 97 HOH HOH D . QA 10 HOH 53 653 77 HOH HOH D . QA 10 HOH 54 654 102 HOH HOH D . QA 10 HOH 55 655 84 HOH HOH D . QA 10 HOH 56 656 188 HOH HOH D . QA 10 HOH 57 657 20 HOH HOH D . QA 10 HOH 58 658 106 HOH HOH D . QA 10 HOH 59 659 85 HOH HOH D . QA 10 HOH 60 660 12 HOH HOH D . QA 10 HOH 61 661 93 HOH HOH D . QA 10 HOH 62 662 45 HOH HOH D . QA 10 HOH 63 663 180 HOH HOH D . QA 10 HOH 64 664 43 HOH HOH D . QA 10 HOH 65 665 76 HOH HOH D . QA 10 HOH 66 666 89 HOH HOH D . QA 10 HOH 67 667 132 HOH HOH D . RA 10 HOH 1 601 99 HOH HOH E . RA 10 HOH 2 602 117 HOH HOH E . RA 10 HOH 3 603 133 HOH HOH E . RA 10 HOH 4 604 161 HOH HOH E . RA 10 HOH 5 605 160 HOH HOH E . RA 10 HOH 6 606 158 HOH HOH E . RA 10 HOH 7 607 138 HOH HOH E . RA 10 HOH 8 608 25 HOH HOH E . RA 10 HOH 9 609 37 HOH HOH E . RA 10 HOH 10 610 186 HOH HOH E . RA 10 HOH 11 611 75 HOH HOH E . RA 10 HOH 12 612 166 HOH HOH E . RA 10 HOH 13 613 72 HOH HOH E . RA 10 HOH 14 614 145 HOH HOH E . RA 10 HOH 15 615 185 HOH HOH E . RA 10 HOH 16 616 126 HOH HOH E . RA 10 HOH 17 617 110 HOH HOH E . RA 10 HOH 18 618 116 HOH HOH E . RA 10 HOH 19 619 71 HOH HOH E . RA 10 HOH 20 620 73 HOH HOH E . RA 10 HOH 21 621 169 HOH HOH E . RA 10 HOH 22 622 44 HOH HOH E . RA 10 HOH 23 623 36 HOH HOH E . RA 10 HOH 24 624 151 HOH HOH E . RA 10 HOH 25 625 31 HOH HOH E . RA 10 HOH 26 626 114 HOH HOH E . RA 10 HOH 27 627 135 HOH HOH E . RA 10 HOH 28 628 86 HOH HOH E . RA 10 HOH 29 629 150 HOH HOH E . RA 10 HOH 30 630 142 HOH HOH E . RA 10 HOH 31 631 115 HOH HOH E . RA 10 HOH 32 632 122 HOH HOH E . # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA trimeric 3 2 author_and_software_defined_assembly PISA trimeric 3 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,B,C,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,NA,OA,PA 2 1 D,E,F,W,X,Y,Z,AA,BA,CA,DA,EA,FA,GA,HA,IA,JA,KA,LA,MA,QA,RA # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 8720 ? 1 MORE 44 ? 1 'SSA (A^2)' 21170 ? 2 'ABSA (A^2)' 8700 ? 2 MORE 48 ? 2 'SSA (A^2)' 20860 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2016-03-30 2 'Structure model' 1 1 2016-04-27 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.7.0017 1 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? SCALA ? ? ? 3.3.20 2 ? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? 3.15 3 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? iMOSFLM ? ? ? . 4 ? phasing ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? . 5 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 CG _pdbx_validate_rmsd_bond.auth_asym_id_1 D _pdbx_validate_rmsd_bond.auth_comp_id_1 LYS _pdbx_validate_rmsd_bond.auth_seq_id_1 360 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 ? _pdbx_validate_rmsd_bond.auth_atom_id_2 CD _pdbx_validate_rmsd_bond.auth_asym_id_2 D _pdbx_validate_rmsd_bond.auth_comp_id_2 LYS _pdbx_validate_rmsd_bond.auth_seq_id_2 360 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 ? _pdbx_validate_rmsd_bond.bond_value 1.272 _pdbx_validate_rmsd_bond.bond_target_value 1.520 _pdbx_validate_rmsd_bond.bond_deviation -0.248 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.034 _pdbx_validate_rmsd_bond.linker_flag N # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 CB _pdbx_validate_rmsd_angle.auth_asym_id_1 D _pdbx_validate_rmsd_angle.auth_comp_id_1 LYS _pdbx_validate_rmsd_angle.auth_seq_id_1 360 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CG _pdbx_validate_rmsd_angle.auth_asym_id_2 D _pdbx_validate_rmsd_angle.auth_comp_id_2 LYS _pdbx_validate_rmsd_angle.auth_seq_id_2 360 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 CD _pdbx_validate_rmsd_angle.auth_asym_id_3 D _pdbx_validate_rmsd_angle.auth_comp_id_3 LYS _pdbx_validate_rmsd_angle.auth_seq_id_3 360 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 144.66 _pdbx_validate_rmsd_angle.angle_target_value 111.60 _pdbx_validate_rmsd_angle.angle_deviation 33.06 _pdbx_validate_rmsd_angle.angle_standard_deviation 2.60 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 SER A 298 ? ? 92.72 -10.88 2 1 ALA B 327 ? ? -91.45 44.34 3 1 THR B 359 ? ? -94.23 42.32 4 1 PRO B 374 ? ? -69.07 -177.02 5 1 VAL C 10 ? ? -90.16 -65.43 6 1 SER D 298 ? ? 107.56 -21.02 7 1 ALA D 339 ? ? -38.99 132.05 8 1 ASN D 390 ? ? -80.65 49.85 9 1 ASN D 434 ? ? 48.83 25.68 10 1 THR E 359 ? ? -93.60 54.20 11 1 ASN E 390 ? ? -93.29 46.78 12 1 VAL F 10 ? ? -92.56 -64.03 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A LYS 326 ? CD ? A LYS 106 CD 2 1 Y 1 A LYS 326 ? CE ? A LYS 106 CE 3 1 Y 1 A LYS 326 ? NZ ? A LYS 106 NZ 4 1 Y 1 A ARG 355 ? CG ? A ARG 135 CG 5 1 Y 1 A ARG 355 ? CD ? A ARG 135 CD 6 1 Y 1 A ARG 355 ? NE ? A ARG 135 NE 7 1 Y 1 A ARG 355 ? CZ ? A ARG 135 CZ 8 1 Y 1 A ARG 355 ? NH1 ? A ARG 135 NH1 9 1 Y 1 A ARG 355 ? NH2 ? A ARG 135 NH2 10 1 Y 1 A LYS 360 ? CD ? A LYS 140 CD 11 1 Y 1 A LYS 360 ? CE ? A LYS 140 CE 12 1 Y 1 A LYS 360 ? NZ ? A LYS 140 NZ 13 1 Y 1 A LYS 370 ? CE ? A LYS 150 CE 14 1 Y 1 A LYS 370 ? NZ ? A LYS 150 NZ 15 1 Y 1 B LYS 248 ? NZ ? B LYS 41 NZ 16 1 Y 1 B GLU 269 ? CG ? B GLU 62 CG 17 1 Y 1 B GLU 269 ? CD ? B GLU 62 CD 18 1 Y 1 B GLU 269 ? OE1 ? B GLU 62 OE1 19 1 Y 1 B GLU 269 ? OE2 ? B GLU 62 OE2 20 1 Y 1 B ASP 270 ? CG ? B ASP 63 CG 21 1 Y 1 B ASP 270 ? OD1 ? B ASP 63 OD1 22 1 Y 1 B ASP 270 ? OD2 ? B ASP 63 OD2 23 1 Y 1 B GLU 293 ? CG ? B GLU 86 CG 24 1 Y 1 B GLU 293 ? CD ? B GLU 86 CD 25 1 Y 1 B GLU 293 ? OE1 ? B GLU 86 OE1 26 1 Y 1 B GLU 293 ? OE2 ? B GLU 86 OE2 27 1 Y 1 B TYR 296 ? CG ? B TYR 89 CG 28 1 Y 1 B TYR 296 ? CD1 ? B TYR 89 CD1 29 1 Y 1 B TYR 296 ? CD2 ? B TYR 89 CD2 30 1 Y 1 B TYR 296 ? CE1 ? B TYR 89 CE1 31 1 Y 1 B TYR 296 ? CE2 ? B TYR 89 CE2 32 1 Y 1 B TYR 296 ? CZ ? B TYR 89 CZ 33 1 Y 1 B TYR 296 ? OH ? B TYR 89 OH 34 1 Y 1 B GLN 311 ? CG ? B GLN 104 CG 35 1 Y 1 B GLN 311 ? CD ? B GLN 104 CD 36 1 Y 1 B GLN 311 ? OE1 ? B GLN 104 OE1 37 1 Y 1 B GLN 311 ? NE2 ? B GLN 104 NE2 38 1 Y 1 B LYS 326 ? CG ? B LYS 119 CG 39 1 Y 1 B LYS 326 ? CD ? B LYS 119 CD 40 1 Y 1 B LYS 326 ? CE ? B LYS 119 CE 41 1 Y 1 B LYS 326 ? NZ ? B LYS 119 NZ 42 1 Y 1 B LYS 340 ? NZ ? B LYS 133 NZ 43 1 Y 1 B ARG 355 ? CG ? B ARG 148 CG 44 1 Y 1 B ARG 355 ? CD ? B ARG 148 CD 45 1 Y 1 B ARG 355 ? NE ? B ARG 148 NE 46 1 Y 1 B ARG 355 ? CZ ? B ARG 148 CZ 47 1 Y 1 B ARG 355 ? NH1 ? B ARG 148 NH1 48 1 Y 1 B ARG 355 ? NH2 ? B ARG 148 NH2 49 1 Y 1 B THR 359 ? OG1 ? B THR 152 OG1 50 1 Y 1 B THR 359 ? CG2 ? B THR 152 CG2 51 1 Y 1 B LYS 360 ? CE ? B LYS 153 CE 52 1 Y 1 B LYS 360 ? NZ ? B LYS 153 NZ 53 1 Y 1 B ASN 361 ? CG ? B ASN 154 CG 54 1 Y 1 B ASN 361 ? OD1 ? B ASN 154 OD1 55 1 Y 1 B ASN 361 ? ND2 ? B ASN 154 ND2 56 1 Y 1 B GLN 386 ? CG ? B GLN 179 CG 57 1 Y 1 B GLN 386 ? CD ? B GLN 179 CD 58 1 Y 1 B GLN 386 ? OE1 ? B GLN 179 OE1 59 1 Y 1 B GLN 386 ? NE2 ? B GLN 179 NE2 60 1 Y 1 B ASN 389 ? CG ? B ASN 182 CG 61 1 Y 1 B ASN 389 ? OD1 ? B ASN 182 OD1 62 1 Y 1 B ASN 389 ? ND2 ? B ASN 182 ND2 63 1 Y 1 B ASP 413 ? CG ? B ASP 206 CG 64 1 Y 1 B ASP 413 ? OD1 ? B ASP 206 OD1 65 1 Y 1 B ASP 413 ? OD2 ? B ASP 206 OD2 66 1 Y 1 B LYS 414 ? CG ? B LYS 207 CG 67 1 Y 1 B LYS 414 ? CD ? B LYS 207 CD 68 1 Y 1 B LYS 414 ? CE ? B LYS 207 CE 69 1 Y 1 B LYS 414 ? NZ ? B LYS 207 NZ 70 1 Y 1 B SER 415 ? OG ? B SER 208 OG 71 1 Y 1 B GLN 419 ? CG ? B GLN 212 CG 72 1 Y 1 B GLN 419 ? CD ? B GLN 212 CD 73 1 Y 1 B GLN 419 ? OE1 ? B GLN 212 OE1 74 1 Y 1 B GLN 419 ? NE2 ? B GLN 212 NE2 75 1 Y 1 B ASN 421 ? CG ? B ASN 214 CG 76 1 Y 1 B ASN 421 ? OD1 ? B ASN 214 OD1 77 1 Y 1 B ASN 421 ? ND2 ? B ASN 214 ND2 78 1 Y 1 D LYS 288 ? NZ ? D LYS 68 NZ 79 1 Y 1 D LYS 322 ? CE ? D LYS 102 CE 80 1 Y 1 D LYS 322 ? NZ ? D LYS 102 NZ 81 1 Y 1 D LYS 340 ? CE ? D LYS 120 CE 82 1 Y 1 D LYS 340 ? NZ ? D LYS 120 NZ 83 1 Y 1 D ARG 355 ? CG ? D ARG 135 CG 84 1 Y 1 D ARG 355 ? CD ? D ARG 135 CD 85 1 Y 1 D ARG 355 ? NE ? D ARG 135 NE 86 1 Y 1 D ARG 355 ? CZ ? D ARG 135 CZ 87 1 Y 1 D ARG 355 ? NH1 ? D ARG 135 NH1 88 1 Y 1 D ARG 355 ? NH2 ? D ARG 135 NH2 89 1 Y 1 D LYS 360 ? CE ? D LYS 140 CE 90 1 Y 1 D LYS 360 ? NZ ? D LYS 140 NZ 91 1 Y 0 D LYS 360 ? CD ? D LYS 140 CD 92 1 Y 1 D LYS 370 ? CE ? D LYS 150 CE 93 1 Y 1 D LYS 370 ? NZ ? D LYS 150 NZ 94 1 Y 1 D LYS 414 ? NZ ? D LYS 194 NZ 95 1 Y 1 E GLU 269 ? CG ? E GLU 62 CG 96 1 Y 1 E GLU 269 ? CD ? E GLU 62 CD 97 1 Y 1 E GLU 269 ? OE1 ? E GLU 62 OE1 98 1 Y 1 E GLU 269 ? OE2 ? E GLU 62 OE2 99 1 Y 1 E ASP 270 ? CG ? E ASP 63 CG 100 1 Y 1 E ASP 270 ? OD1 ? E ASP 63 OD1 101 1 Y 1 E ASP 270 ? OD2 ? E ASP 63 OD2 102 1 Y 1 E GLU 272 ? CG ? E GLU 65 CG 103 1 Y 1 E GLU 272 ? CD ? E GLU 65 CD 104 1 Y 1 E GLU 272 ? OE1 ? E GLU 65 OE1 105 1 Y 1 E GLU 272 ? OE2 ? E GLU 65 OE2 106 1 Y 1 E LYS 274 ? CG ? E LYS 67 CG 107 1 Y 1 E LYS 274 ? CD ? E LYS 67 CD 108 1 Y 1 E LYS 274 ? CE ? E LYS 67 CE 109 1 Y 1 E LYS 274 ? NZ ? E LYS 67 NZ 110 1 Y 1 E TYR 296 ? CG ? E TYR 89 CG 111 1 Y 1 E TYR 296 ? CD1 ? E TYR 89 CD1 112 1 Y 1 E TYR 296 ? CD2 ? E TYR 89 CD2 113 1 Y 1 E TYR 296 ? CE1 ? E TYR 89 CE1 114 1 Y 1 E TYR 296 ? CE2 ? E TYR 89 CE2 115 1 Y 1 E TYR 296 ? CZ ? E TYR 89 CZ 116 1 Y 1 E TYR 296 ? OH ? E TYR 89 OH 117 1 Y 1 E SER 298 ? OG ? E SER 91 OG 118 1 Y 1 E GLN 311 ? CG ? E GLN 104 CG 119 1 Y 1 E GLN 311 ? CD ? E GLN 104 CD 120 1 Y 1 E GLN 311 ? OE1 ? E GLN 104 OE1 121 1 Y 1 E GLN 311 ? NE2 ? E GLN 104 NE2 122 1 Y 1 E LYS 326 ? CG ? E LYS 119 CG 123 1 Y 1 E LYS 326 ? CD ? E LYS 119 CD 124 1 Y 1 E LYS 326 ? CE ? E LYS 119 CE 125 1 Y 1 E LYS 326 ? NZ ? E LYS 119 NZ 126 1 Y 1 E ARG 355 ? CG ? E ARG 148 CG 127 1 Y 1 E ARG 355 ? CD ? E ARG 148 CD 128 1 Y 1 E ARG 355 ? NE ? E ARG 148 NE 129 1 Y 1 E ARG 355 ? CZ ? E ARG 148 CZ 130 1 Y 1 E ARG 355 ? NH1 ? E ARG 148 NH1 131 1 Y 1 E ARG 355 ? NH2 ? E ARG 148 NH2 132 1 Y 1 E GLU 356 ? CG ? E GLU 149 CG 133 1 Y 1 E GLU 356 ? CD ? E GLU 149 CD 134 1 Y 1 E GLU 356 ? OE1 ? E GLU 149 OE1 135 1 Y 1 E GLU 356 ? OE2 ? E GLU 149 OE2 136 1 Y 1 E ASN 361 ? CG ? E ASN 154 CG 137 1 Y 1 E ASN 361 ? OD1 ? E ASN 154 OD1 138 1 Y 1 E ASN 361 ? ND2 ? E ASN 154 ND2 139 1 Y 1 E ASN 384 ? CG ? E ASN 177 CG 140 1 Y 1 E ASN 384 ? OD1 ? E ASN 177 OD1 141 1 Y 1 E ASN 384 ? ND2 ? E ASN 177 ND2 142 1 Y 1 E ASP 413 ? CG ? E ASP 206 CG 143 1 Y 1 E ASP 413 ? OD1 ? E ASP 206 OD1 144 1 Y 1 E ASP 413 ? OD2 ? E ASP 206 OD2 145 1 Y 1 E LYS 414 ? CG ? E LYS 207 CG 146 1 Y 1 E LYS 414 ? CD ? E LYS 207 CD 147 1 Y 1 E LYS 414 ? CE ? E LYS 207 CE 148 1 Y 1 E LYS 414 ? NZ ? E LYS 207 NZ 149 1 Y 1 E SER 415 ? OG ? E SER 208 OG 150 1 Y 1 E ARG 416 ? CG ? E ARG 209 CG 151 1 Y 1 E ARG 416 ? CD ? E ARG 209 CD 152 1 Y 1 E ARG 416 ? NE ? E ARG 209 NE 153 1 Y 1 E ARG 416 ? CZ ? E ARG 209 CZ 154 1 Y 1 E ARG 416 ? NH1 ? E ARG 209 NH1 155 1 Y 1 E ARG 416 ? NH2 ? E ARG 209 NH2 156 1 Y 1 E GLN 418 ? CG ? E GLN 211 CG 157 1 Y 1 E GLN 418 ? CD ? E GLN 211 CD 158 1 Y 1 E GLN 418 ? OE1 ? E GLN 211 OE1 159 1 Y 1 E GLN 418 ? NE2 ? E GLN 211 NE2 160 1 Y 1 E GLN 419 ? CG ? E GLN 212 CG 161 1 Y 1 E GLN 419 ? CD ? E GLN 212 CD 162 1 Y 1 E GLN 419 ? OE1 ? E GLN 212 OE1 163 1 Y 1 E GLN 419 ? NE2 ? E GLN 212 NE2 164 1 Y 1 E HIS 433 ? CG ? E HIS 226 CG 165 1 Y 1 E HIS 433 ? ND1 ? E HIS 226 ND1 166 1 Y 1 E HIS 433 ? CD2 ? E HIS 226 CD2 167 1 Y 1 E HIS 433 ? CE1 ? E HIS 226 CE1 168 1 Y 1 E HIS 433 ? NE2 ? E HIS 226 NE2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ASP 221 ? A ASP 1 2 1 Y 1 A LYS 222 ? A LYS 2 3 1 Y 1 A THR 223 ? A THR 3 4 1 Y 1 A HIS 224 ? A HIS 4 5 1 Y 1 A THR 225 ? A THR 5 6 1 Y 1 A CYS 226 ? A CYS 6 7 1 Y 1 A PRO 227 ? A PRO 7 8 1 Y 1 A PRO 228 ? A PRO 8 9 1 Y 1 A CYS 229 ? A CYS 9 10 1 Y 1 A PRO 230 ? A PRO 10 11 1 Y 1 A ALA 231 ? A ALA 11 12 1 Y 1 A PRO 232 ? A PRO 12 13 1 Y 1 A GLU 233 ? A GLU 13 14 1 Y 1 A LEU 234 ? A LEU 14 15 1 Y 1 A LEU 235 ? A LEU 15 16 1 Y 1 A GLY 236 ? A GLY 16 17 1 Y 1 A SER 444 ? A SER 224 18 1 Y 1 A PRO 445 ? A PRO 225 19 1 Y 1 A GLY 446 ? A GLY 226 20 1 Y 1 A LYS 447 ? A LYS 227 21 1 Y 1 B HIS 208 ? B HIS 1 22 1 Y 1 B HIS 209 ? B HIS 2 23 1 Y 1 B HIS 210 ? B HIS 3 24 1 Y 1 B HIS 211 ? B HIS 4 25 1 Y 1 B HIS 212 ? B HIS 5 26 1 Y 1 B HIS 213 ? B HIS 6 27 1 Y 1 B HIS 214 ? B HIS 7 28 1 Y 1 B HIS 215 ? B HIS 8 29 1 Y 1 B SER 216 ? B SER 9 30 1 Y 1 B GLY 217 ? B GLY 10 31 1 Y 1 B SER 218 ? B SER 11 32 1 Y 1 B GLY 219 ? B GLY 12 33 1 Y 1 B SER 220 ? B SER 13 34 1 Y 1 B ASP 221 ? B ASP 14 35 1 Y 1 B LYS 222 ? B LYS 15 36 1 Y 1 B THR 223 ? B THR 16 37 1 Y 1 B HIS 224 ? B HIS 17 38 1 Y 1 B THR 225 ? B THR 18 39 1 Y 1 B CYS 226 ? B CYS 19 40 1 Y 1 B PRO 227 ? B PRO 20 41 1 Y 1 B PRO 228 ? B PRO 21 42 1 Y 1 B CYS 229 ? B CYS 22 43 1 Y 1 B PRO 230 ? B PRO 23 44 1 Y 1 B ALA 231 ? B ALA 24 45 1 Y 1 B PRO 232 ? B PRO 25 46 1 Y 1 B GLU 233 ? B GLU 26 47 1 Y 1 B LEU 234 ? B LEU 27 48 1 Y 1 B LEU 235 ? B LEU 28 49 1 Y 1 B GLY 236 ? B GLY 29 50 1 Y 1 B GLY 420 ? B GLY 213 51 1 Y 1 B SER 444 ? B SER 237 52 1 Y 1 B PRO 445 ? B PRO 238 53 1 Y 1 B GLY 446 ? B GLY 239 54 1 Y 1 B LYS 447 ? B LYS 240 55 1 Y 1 D ASP 221 ? D ASP 1 56 1 Y 1 D LYS 222 ? D LYS 2 57 1 Y 1 D THR 223 ? D THR 3 58 1 Y 1 D HIS 224 ? D HIS 4 59 1 Y 1 D THR 225 ? D THR 5 60 1 Y 1 D CYS 226 ? D CYS 6 61 1 Y 1 D PRO 227 ? D PRO 7 62 1 Y 1 D PRO 228 ? D PRO 8 63 1 Y 1 D CYS 229 ? D CYS 9 64 1 Y 1 D PRO 230 ? D PRO 10 65 1 Y 1 D ALA 231 ? D ALA 11 66 1 Y 1 D PRO 232 ? D PRO 12 67 1 Y 1 D GLU 233 ? D GLU 13 68 1 Y 1 D LEU 234 ? D LEU 14 69 1 Y 1 D LEU 235 ? D LEU 15 70 1 Y 1 D GLY 236 ? D GLY 16 71 1 Y 1 D SER 444 ? D SER 224 72 1 Y 1 D PRO 445 ? D PRO 225 73 1 Y 1 D GLY 446 ? D GLY 226 74 1 Y 1 D LYS 447 ? D LYS 227 75 1 Y 1 E HIS 208 ? E HIS 1 76 1 Y 1 E HIS 209 ? E HIS 2 77 1 Y 1 E HIS 210 ? E HIS 3 78 1 Y 1 E HIS 211 ? E HIS 4 79 1 Y 1 E HIS 212 ? E HIS 5 80 1 Y 1 E HIS 213 ? E HIS 6 81 1 Y 1 E HIS 214 ? E HIS 7 82 1 Y 1 E HIS 215 ? E HIS 8 83 1 Y 1 E SER 216 ? E SER 9 84 1 Y 1 E GLY 217 ? E GLY 10 85 1 Y 1 E SER 218 ? E SER 11 86 1 Y 1 E GLY 219 ? E GLY 12 87 1 Y 1 E SER 220 ? E SER 13 88 1 Y 1 E ASP 221 ? E ASP 14 89 1 Y 1 E LYS 222 ? E LYS 15 90 1 Y 1 E THR 223 ? E THR 16 91 1 Y 1 E HIS 224 ? E HIS 17 92 1 Y 1 E THR 225 ? E THR 18 93 1 Y 1 E CYS 226 ? E CYS 19 94 1 Y 1 E PRO 227 ? E PRO 20 95 1 Y 1 E PRO 228 ? E PRO 21 96 1 Y 1 E CYS 229 ? E CYS 22 97 1 Y 1 E PRO 230 ? E PRO 23 98 1 Y 1 E ALA 231 ? E ALA 24 99 1 Y 1 E PRO 232 ? E PRO 25 100 1 Y 1 E GLU 233 ? E GLU 26 101 1 Y 1 E LEU 234 ? E LEU 27 102 1 Y 1 E LEU 235 ? E LEU 28 103 1 Y 1 E GLY 236 ? E GLY 29 104 1 Y 1 E SER 444 ? E SER 237 105 1 Y 1 E PRO 445 ? E PRO 238 106 1 Y 1 E GLY 446 ? E GLY 239 107 1 Y 1 E LYS 447 ? E LYS 240 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 4 N-ACETYL-D-GLUCOSAMINE NAG 5 BETA-D-MANNOSE BMA 6 ALPHA-D-MANNOSE MAN 7 BETA-D-GALACTOSE GAL 8 ALPHA-L-FUCOSE FUC 9 'IODIDE ION' IOD 10 water HOH #