data_5DF0 # _entry.id 5DF0 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.285 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5DF0 WWPDB D_1000213110 # _pdbx_database_related.db_name PDB _pdbx_database_related.details . _pdbx_database_related.db_id 5DEZ _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5DF0 _pdbx_database_status.recvd_initial_deposition_date 2015-08-26 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Mou, T.-C.' 1 'Sprang, S.R.' 2 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country ? _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev 'To Be Published' _citation.journal_id_ASTM ? _citation.journal_id_CSD 0353 _citation.journal_id_ISSN ? _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume ? _citation.language ? _citation.page_first ? _citation.page_last ? _citation.title 'Crystal structure of AcMNPV Chitinase A' _citation.year ? _citation.database_id_CSD ? _citation.pdbx_database_id_DOI ? _citation.pdbx_database_id_PubMed ? _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Mou, T.-C.' 1 primary 'Sprang, S.R.' 2 # _cell.entry_id 5DF0 _cell.length_a 96.712 _cell.length_b 112.766 _cell.length_c 129.591 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? # _symmetry.entry_id 5DF0 _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Ac-ChiA 60875.121 2 3.2.1.14 ? ? ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 6 ? ? ? ? 3 non-polymer syn '2-deoxy-2-(ethanethioylamino)-beta-D-glucopyranose' 237.273 2 ? ? ? ? 4 non-polymer syn '(2R,3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methylhexahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol' 221.274 2 ? ? ? ? 5 non-polymer man 'CHLORIDE ION' 35.453 1 ? ? ? ? 6 non-polymer man 'SULFATE ION' 96.063 5 ? ? ? ? 7 water nat water 18.015 16 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name Chitinase # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;MLYKLLNVLWLVAVSNAIPGTPVIDWADRNYALVEINYEATAYENLIKPKEQVDVQVSWNVWNGDIGDIAYVLFDEQQVW KGDAESKRATIKVLVSGQFNMRVKLCNEDGCSVSDPVLVKVADTDGGHLAPLEYTWLENNKPGRREDKIVAAYFVEWGVY GRNFPVDKVPLPNLSHLLYGFIPICGGDGINDALKTISGSFESLQRSCKGREDFKVAIHDPWAAVQKPQKSVSAWNEPYK GNFGQLMAAKLANPHLKILPSIGGWTLSDPFYFMHDVEKRNVFVDSVKEFLQVWKFFDGVDVDWEFPGGKGANPSLGDAE RDAKTYILLLEELRAMLDDLEAQTGRVYELTSAISAGYDKIAVVNYAEAQKSLGKIFLMSYDFKGAWSNTDLGYQTTVYA PSWNSEELYTTHYAVDALLKQGVDPNKIIVGVAMYGRGWTGVTNYTNDNYFSGTGNGPVSGTWEDGVVDYRQIQKDLNNY VYTFDSAAQASYVFDKSKGDLISFDSVDSVLGKVKYVDRNKLGGLFAWEIDADNGDLLNAINAQF ; _entity_poly.pdbx_seq_one_letter_code_can ;MLYKLLNVLWLVAVSNAIPGTPVIDWADRNYALVEINYEATAYENLIKPKEQVDVQVSWNVWNGDIGDIAYVLFDEQQVW KGDAESKRATIKVLVSGQFNMRVKLCNEDGCSVSDPVLVKVADTDGGHLAPLEYTWLENNKPGRREDKIVAAYFVEWGVY GRNFPVDKVPLPNLSHLLYGFIPICGGDGINDALKTISGSFESLQRSCKGREDFKVAIHDPWAAVQKPQKSVSAWNEPYK GNFGQLMAAKLANPHLKILPSIGGWTLSDPFYFMHDVEKRNVFVDSVKEFLQVWKFFDGVDVDWEFPGGKGANPSLGDAE RDAKTYILLLEELRAMLDDLEAQTGRVYELTSAISAGYDKIAVVNYAEAQKSLGKIFLMSYDFKGAWSNTDLGYQTTVYA PSWNSEELYTTHYAVDALLKQGVDPNKIIVGVAMYGRGWTGVTNYTNDNYFSGTGNGPVSGTWEDGVVDYRQIQKDLNNY VYTFDSAAQASYVFDKSKGDLISFDSVDSVLGKVKYVDRNKLGGLFAWEIDADNGDLLNAINAQF ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 MET n 1 2 LEU n 1 3 TYR n 1 4 LYS n 1 5 LEU n 1 6 LEU n 1 7 ASN n 1 8 VAL n 1 9 LEU n 1 10 TRP n 1 11 LEU n 1 12 VAL n 1 13 ALA n 1 14 VAL n 1 15 SER n 1 16 ASN n 1 17 ALA n 1 18 ILE n 1 19 PRO n 1 20 GLY n 1 21 THR n 1 22 PRO n 1 23 VAL n 1 24 ILE n 1 25 ASP n 1 26 TRP n 1 27 ALA n 1 28 ASP n 1 29 ARG n 1 30 ASN n 1 31 TYR n 1 32 ALA n 1 33 LEU n 1 34 VAL n 1 35 GLU n 1 36 ILE n 1 37 ASN n 1 38 TYR n 1 39 GLU n 1 40 ALA n 1 41 THR n 1 42 ALA n 1 43 TYR n 1 44 GLU n 1 45 ASN n 1 46 LEU n 1 47 ILE n 1 48 LYS n 1 49 PRO n 1 50 LYS n 1 51 GLU n 1 52 GLN n 1 53 VAL n 1 54 ASP n 1 55 VAL n 1 56 GLN n 1 57 VAL n 1 58 SER n 1 59 TRP n 1 60 ASN n 1 61 VAL n 1 62 TRP n 1 63 ASN n 1 64 GLY n 1 65 ASP n 1 66 ILE n 1 67 GLY n 1 68 ASP n 1 69 ILE n 1 70 ALA n 1 71 TYR n 1 72 VAL n 1 73 LEU n 1 74 PHE n 1 75 ASP n 1 76 GLU n 1 77 GLN n 1 78 GLN n 1 79 VAL n 1 80 TRP n 1 81 LYS n 1 82 GLY n 1 83 ASP n 1 84 ALA n 1 85 GLU n 1 86 SER n 1 87 LYS n 1 88 ARG n 1 89 ALA n 1 90 THR n 1 91 ILE n 1 92 LYS n 1 93 VAL n 1 94 LEU n 1 95 VAL n 1 96 SER n 1 97 GLY n 1 98 GLN n 1 99 PHE n 1 100 ASN n 1 101 MET n 1 102 ARG n 1 103 VAL n 1 104 LYS n 1 105 LEU n 1 106 CYS n 1 107 ASN n 1 108 GLU n 1 109 ASP n 1 110 GLY n 1 111 CYS n 1 112 SER n 1 113 VAL n 1 114 SER n 1 115 ASP n 1 116 PRO n 1 117 VAL n 1 118 LEU n 1 119 VAL n 1 120 LYS n 1 121 VAL n 1 122 ALA n 1 123 ASP n 1 124 THR n 1 125 ASP n 1 126 GLY n 1 127 GLY n 1 128 HIS n 1 129 LEU n 1 130 ALA n 1 131 PRO n 1 132 LEU n 1 133 GLU n 1 134 TYR n 1 135 THR n 1 136 TRP n 1 137 LEU n 1 138 GLU n 1 139 ASN n 1 140 ASN n 1 141 LYS n 1 142 PRO n 1 143 GLY n 1 144 ARG n 1 145 ARG n 1 146 GLU n 1 147 ASP n 1 148 LYS n 1 149 ILE n 1 150 VAL n 1 151 ALA n 1 152 ALA n 1 153 TYR n 1 154 PHE n 1 155 VAL n 1 156 GLU n 1 157 TRP n 1 158 GLY n 1 159 VAL n 1 160 TYR n 1 161 GLY n 1 162 ARG n 1 163 ASN n 1 164 PHE n 1 165 PRO n 1 166 VAL n 1 167 ASP n 1 168 LYS n 1 169 VAL n 1 170 PRO n 1 171 LEU n 1 172 PRO n 1 173 ASN n 1 174 LEU n 1 175 SER n 1 176 HIS n 1 177 LEU n 1 178 LEU n 1 179 TYR n 1 180 GLY n 1 181 PHE n 1 182 ILE n 1 183 PRO n 1 184 ILE n 1 185 CYS n 1 186 GLY n 1 187 GLY n 1 188 ASP n 1 189 GLY n 1 190 ILE n 1 191 ASN n 1 192 ASP n 1 193 ALA n 1 194 LEU n 1 195 LYS n 1 196 THR n 1 197 ILE n 1 198 SER n 1 199 GLY n 1 200 SER n 1 201 PHE n 1 202 GLU n 1 203 SER n 1 204 LEU n 1 205 GLN n 1 206 ARG n 1 207 SER n 1 208 CYS n 1 209 LYS n 1 210 GLY n 1 211 ARG n 1 212 GLU n 1 213 ASP n 1 214 PHE n 1 215 LYS n 1 216 VAL n 1 217 ALA n 1 218 ILE n 1 219 HIS n 1 220 ASP n 1 221 PRO n 1 222 TRP n 1 223 ALA n 1 224 ALA n 1 225 VAL n 1 226 GLN n 1 227 LYS n 1 228 PRO n 1 229 GLN n 1 230 LYS n 1 231 SER n 1 232 VAL n 1 233 SER n 1 234 ALA n 1 235 TRP n 1 236 ASN n 1 237 GLU n 1 238 PRO n 1 239 TYR n 1 240 LYS n 1 241 GLY n 1 242 ASN n 1 243 PHE n 1 244 GLY n 1 245 GLN n 1 246 LEU n 1 247 MET n 1 248 ALA n 1 249 ALA n 1 250 LYS n 1 251 LEU n 1 252 ALA n 1 253 ASN n 1 254 PRO n 1 255 HIS n 1 256 LEU n 1 257 LYS n 1 258 ILE n 1 259 LEU n 1 260 PRO n 1 261 SER n 1 262 ILE n 1 263 GLY n 1 264 GLY n 1 265 TRP n 1 266 THR n 1 267 LEU n 1 268 SER n 1 269 ASP n 1 270 PRO n 1 271 PHE n 1 272 TYR n 1 273 PHE n 1 274 MET n 1 275 HIS n 1 276 ASP n 1 277 VAL n 1 278 GLU n 1 279 LYS n 1 280 ARG n 1 281 ASN n 1 282 VAL n 1 283 PHE n 1 284 VAL n 1 285 ASP n 1 286 SER n 1 287 VAL n 1 288 LYS n 1 289 GLU n 1 290 PHE n 1 291 LEU n 1 292 GLN n 1 293 VAL n 1 294 TRP n 1 295 LYS n 1 296 PHE n 1 297 PHE n 1 298 ASP n 1 299 GLY n 1 300 VAL n 1 301 ASP n 1 302 VAL n 1 303 ASP n 1 304 TRP n 1 305 GLU n 1 306 PHE n 1 307 PRO n 1 308 GLY n 1 309 GLY n 1 310 LYS n 1 311 GLY n 1 312 ALA n 1 313 ASN n 1 314 PRO n 1 315 SER n 1 316 LEU n 1 317 GLY n 1 318 ASP n 1 319 ALA n 1 320 GLU n 1 321 ARG n 1 322 ASP n 1 323 ALA n 1 324 LYS n 1 325 THR n 1 326 TYR n 1 327 ILE n 1 328 LEU n 1 329 LEU n 1 330 LEU n 1 331 GLU n 1 332 GLU n 1 333 LEU n 1 334 ARG n 1 335 ALA n 1 336 MET n 1 337 LEU n 1 338 ASP n 1 339 ASP n 1 340 LEU n 1 341 GLU n 1 342 ALA n 1 343 GLN n 1 344 THR n 1 345 GLY n 1 346 ARG n 1 347 VAL n 1 348 TYR n 1 349 GLU n 1 350 LEU n 1 351 THR n 1 352 SER n 1 353 ALA n 1 354 ILE n 1 355 SER n 1 356 ALA n 1 357 GLY n 1 358 TYR n 1 359 ASP n 1 360 LYS n 1 361 ILE n 1 362 ALA n 1 363 VAL n 1 364 VAL n 1 365 ASN n 1 366 TYR n 1 367 ALA n 1 368 GLU n 1 369 ALA n 1 370 GLN n 1 371 LYS n 1 372 SER n 1 373 LEU n 1 374 GLY n 1 375 LYS n 1 376 ILE n 1 377 PHE n 1 378 LEU n 1 379 MET n 1 380 SER n 1 381 TYR n 1 382 ASP n 1 383 PHE n 1 384 LYS n 1 385 GLY n 1 386 ALA n 1 387 TRP n 1 388 SER n 1 389 ASN n 1 390 THR n 1 391 ASP n 1 392 LEU n 1 393 GLY n 1 394 TYR n 1 395 GLN n 1 396 THR n 1 397 THR n 1 398 VAL n 1 399 TYR n 1 400 ALA n 1 401 PRO n 1 402 SER n 1 403 TRP n 1 404 ASN n 1 405 SER n 1 406 GLU n 1 407 GLU n 1 408 LEU n 1 409 TYR n 1 410 THR n 1 411 THR n 1 412 HIS n 1 413 TYR n 1 414 ALA n 1 415 VAL n 1 416 ASP n 1 417 ALA n 1 418 LEU n 1 419 LEU n 1 420 LYS n 1 421 GLN n 1 422 GLY n 1 423 VAL n 1 424 ASP n 1 425 PRO n 1 426 ASN n 1 427 LYS n 1 428 ILE n 1 429 ILE n 1 430 VAL n 1 431 GLY n 1 432 VAL n 1 433 ALA n 1 434 MET n 1 435 TYR n 1 436 GLY n 1 437 ARG n 1 438 GLY n 1 439 TRP n 1 440 THR n 1 441 GLY n 1 442 VAL n 1 443 THR n 1 444 ASN n 1 445 TYR n 1 446 THR n 1 447 ASN n 1 448 ASP n 1 449 ASN n 1 450 TYR n 1 451 PHE n 1 452 SER n 1 453 GLY n 1 454 THR n 1 455 GLY n 1 456 ASN n 1 457 GLY n 1 458 PRO n 1 459 VAL n 1 460 SER n 1 461 GLY n 1 462 THR n 1 463 TRP n 1 464 GLU n 1 465 ASP n 1 466 GLY n 1 467 VAL n 1 468 VAL n 1 469 ASP n 1 470 TYR n 1 471 ARG n 1 472 GLN n 1 473 ILE n 1 474 GLN n 1 475 LYS n 1 476 ASP n 1 477 LEU n 1 478 ASN n 1 479 ASN n 1 480 TYR n 1 481 VAL n 1 482 TYR n 1 483 THR n 1 484 PHE n 1 485 ASP n 1 486 SER n 1 487 ALA n 1 488 ALA n 1 489 GLN n 1 490 ALA n 1 491 SER n 1 492 TYR n 1 493 VAL n 1 494 PHE n 1 495 ASP n 1 496 LYS n 1 497 SER n 1 498 LYS n 1 499 GLY n 1 500 ASP n 1 501 LEU n 1 502 ILE n 1 503 SER n 1 504 PHE n 1 505 ASP n 1 506 SER n 1 507 VAL n 1 508 ASP n 1 509 SER n 1 510 VAL n 1 511 LEU n 1 512 GLY n 1 513 LYS n 1 514 VAL n 1 515 LYS n 1 516 TYR n 1 517 VAL n 1 518 ASP n 1 519 ARG n 1 520 ASN n 1 521 LYS n 1 522 LEU n 1 523 GLY n 1 524 GLY n 1 525 LEU n 1 526 PHE n 1 527 ALA n 1 528 TRP n 1 529 GLU n 1 530 ILE n 1 531 ASP n 1 532 ALA n 1 533 ASP n 1 534 ASN n 1 535 GLY n 1 536 ASP n 1 537 LEU n 1 538 LEU n 1 539 ASN n 1 540 ALA n 1 541 ILE n 1 542 ASN n 1 543 ALA n 1 544 GLN n 1 545 PHE n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 545 _entity_src_gen.gene_src_common_name AcMNPV _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'ChiA, Ac-ChiA' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Autographa californica nuclear polyhedrosis virus' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 46015 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name Alphabaculovirus _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 558016 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code Q70SQ1_NPVAC _struct_ref.pdbx_db_accession Q70SQ1 _struct_ref.pdbx_db_isoform ? _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;MLYKLLNVLWLVAVSNAIPGTPVIDWADRNYALVEINYEATAYENLIKPKEQVDVQVSWNVWNGDIGDIAYVLFDEQQVW KGDAESKRATIKVLVSGQFNMRVKLCNEDGCSVSDPVLVKVADTDGGHLAPLEYTWLENNKPGRREDKIVAAYFVEWGVY GRNFPVDKVPLPNLSHLLYGFIPICGGDGINDALKTISGSFESLQRSCKGREDFKVAIHDPWAAVQKPQKSVSAWNEPYK GNFGQLMAAKLANPHLKILPSIGGWTLSDPFYFMHDVEKRNVFVDSVKEFLQVWKFFDGVDVDWEFPGGKGANPSLGDAE RDAKTYILLLEELRAMLDDLEAQTGRVYELTSAISAGYDKIAVVNYAEAQKSLGKIFLMSYDFKGAWSNTDLGYQTTVYA PSWNSEELYTTHYAVDALLKQGVDPNKIIVGVAMYGRGWTGVTNYTNDNYFSGTGNGPVSGTWEDGVVDYRQIQKDLNNY VYTFDSAAQASYVFDKSKGDLISFDSVDSVLGKVKYVDRNKLGGLFAWEIDADNGDLLNAINAQF ; _struct_ref.pdbx_align_begin 1 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5DF0 A 1 ? 545 ? Q70SQ1 1 ? 545 ? 1 545 2 1 5DF0 B 1 ? 545 ? Q70SQ1 1 ? 545 ? 1 545 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight 58Y non-polymer . '(2R,3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methylhexahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol' ? 'C8 H15 N O4 S' 221.274 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CL non-polymer . 'CHLORIDE ION' ? 'Cl -1' 35.453 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SN5 non-polymer . '2-deoxy-2-(ethanethioylamino)-beta-D-glucopyranose' ? 'C8 H15 N O5 S' 237.273 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5DF0 _exptl.crystals_number 1 _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.87 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 57.14 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details 'Ammonium sulfate, MES' _exptl_crystal_grow.pdbx_pH_range 6.5 # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector PIXEL _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'PSI PILATUS 6M' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2014-07-16 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator 'Si (111)' _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.979 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'SSRL BEAMLINE BL11-1' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.979 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline BL11-1 _diffrn_source.pdbx_synchrotron_site SSRL # _reflns.B_iso_Wilson_estimate ? _reflns.entry_id 5DF0 _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 3.251 _reflns.d_resolution_low 28.09 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 20513 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 89.64 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 5.4 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value 0.125 _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 3.58 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _reflns_shell.d_res_high 3.251 _reflns_shell.d_res_low 3.367 _reflns_shell.meanI_over_sigI_all ? _reflns_shell.meanI_over_sigI_obs 2.13 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_possible ? _reflns_shell.number_unique_all ? _reflns_shell.number_unique_obs ? _reflns_shell.percent_possible_all 81.95 _reflns_shell.percent_possible_obs ? _reflns_shell.Rmerge_F_all ? _reflns_shell.Rmerge_F_obs ? _reflns_shell.Rmerge_I_all ? _reflns_shell.Rmerge_I_obs ? _reflns_shell.meanI_over_sigI_gt ? _reflns_shell.meanI_over_uI_all ? _reflns_shell.meanI_over_uI_gt ? _reflns_shell.number_measured_gt ? _reflns_shell.number_unique_gt ? _reflns_shell.percent_possible_gt ? _reflns_shell.Rmerge_F_gt ? _reflns_shell.Rmerge_I_gt ? _reflns_shell.pdbx_redundancy 2.3 _reflns_shell.pdbx_Rsym_value 0.127 _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_netI_over_sigmaI_all ? _reflns_shell.pdbx_netI_over_sigmaI_obs ? _reflns_shell.pdbx_Rrim_I_all ? _reflns_shell.pdbx_Rpim_I_all ? _reflns_shell.pdbx_rejects ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 _reflns_shell.pdbx_CC_half ? _reflns_shell.pdbx_R_split ? # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 5DF0 _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.ls_number_reflns_obs 20291 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 1.43 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 14.978 _refine.ls_d_res_high 3.251 _refine.ls_percent_reflns_obs 89.58 _refine.ls_R_factor_obs 0.2318 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.2259 _refine.ls_R_factor_R_free 0.2856 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 9.75 _refine.ls_number_reflns_R_free 1978 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean ? _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.11 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.90 _refine.pdbx_ls_cross_valid_method 'FREE R-VALUE' _refine.details ? _refine.pdbx_starting_model 1EDQ _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.43 _refine.pdbx_overall_phase_error 25.47 _refine.overall_SU_B ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8334 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 171 _refine_hist.number_atoms_solvent 16 _refine_hist.number_atoms_total 8521 _refine_hist.d_res_high 3.251 _refine_hist.d_res_low 14.978 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function f_bond_d 0.002 ? ? 8724 'X-RAY DIFFRACTION' ? f_angle_d 0.485 ? ? 11878 'X-RAY DIFFRACTION' ? f_dihedral_angle_d 10.238 ? ? 5008 'X-RAY DIFFRACTION' ? f_chiral_restr 0.043 ? ? 1285 'X-RAY DIFFRACTION' ? f_plane_restr 0.003 ? ? 1520 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.pdbx_refine_id _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_R_work _refine_ls_shell.percent_reflns_obs _refine_ls_shell.R_factor_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.number_reflns_all _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_obs _refine_ls_shell.number_reflns_obs 'X-RAY DIFFRACTION' . 3.2506 3.3310 1174 0.3003 81.00 0.3855 . . 126 . . . . 'X-RAY DIFFRACTION' . 3.3310 3.4200 1203 0.2818 85.00 0.3361 . . 131 . . . . 'X-RAY DIFFRACTION' . 3.4200 3.5194 1247 0.2783 85.00 0.3410 . . 134 . . . . 'X-RAY DIFFRACTION' . 3.5194 3.6314 1175 0.2809 83.00 0.3663 . . 128 . . . . 'X-RAY DIFFRACTION' . 3.6314 3.7593 1196 0.2591 82.00 0.3383 . . 128 . . . . 'X-RAY DIFFRACTION' . 3.7593 3.9072 1345 0.2283 92.00 0.2829 . . 146 . . . . 'X-RAY DIFFRACTION' . 3.9072 4.0816 1347 0.2169 94.00 0.2600 . . 146 . . . . 'X-RAY DIFFRACTION' . 4.0816 4.2920 1377 0.2014 95.00 0.2872 . . 149 . . . . 'X-RAY DIFFRACTION' . 4.2920 4.5538 1370 0.2003 94.00 0.2631 . . 147 . . . . 'X-RAY DIFFRACTION' . 4.5538 4.8940 1363 0.1888 92.00 0.2379 . . 147 . . . . 'X-RAY DIFFRACTION' . 4.8940 5.3658 1328 0.1977 91.00 0.2688 . . 144 . . . . 'X-RAY DIFFRACTION' . 5.3658 6.0960 1337 0.2212 91.00 0.2782 . . 144 . . . . 'X-RAY DIFFRACTION' . 6.0960 7.5152 1428 0.2167 95.00 0.2714 . . 155 . . . . 'X-RAY DIFFRACTION' . 7.5152 14.9781 1423 0.1959 92.00 0.2241 . . 153 . . . . # _struct.entry_id 5DF0 _struct.title 'Crystal structure of AcMNPV Chitinase A in complex WITH CHITOTRIO-THIAZOLINE DITHIOAMIDE' _struct.pdbx_descriptor 'Ac-ChiA (E.C.3.2.1.14)' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5DF0 _struct_keywords.text 'Chitinase, AcMNPV, chitin, Glycosidase, HYDROLASE' _struct_keywords.pdbx_keywords HYDROLASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 3 ? G N N 4 ? H N N 5 ? I N N 6 ? J N N 6 ? K N N 6 ? L N N 2 ? M N N 2 ? N N N 2 ? O N N 3 ? P N N 4 ? Q N N 6 ? R N N 6 ? S N N 7 ? T N N 7 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 TRP A 157 ? TYR A 160 ? TRP A 157 TYR A 160 5 ? 4 HELX_P HELX_P2 AA2 PRO A 165 ? VAL A 169 ? PRO A 165 VAL A 169 5 ? 5 HELX_P HELX_P3 AA3 PRO A 170 ? LEU A 174 ? PRO A 170 LEU A 174 5 ? 5 HELX_P HELX_P4 AA4 ASN A 191 ? ILE A 197 ? ASN A 191 ILE A 197 5 ? 7 HELX_P HELX_P5 AA5 GLY A 199 ? CYS A 208 ? GLY A 199 CYS A 208 1 ? 10 HELX_P HELX_P6 AA6 ASP A 220 ? GLN A 226 ? ASP A 220 GLN A 226 1 ? 7 HELX_P HELX_P7 AA7 LYS A 240 ? ASN A 253 ? LYS A 240 ASN A 253 1 ? 14 HELX_P HELX_P8 AA8 SER A 268 ? MET A 274 ? SER A 268 MET A 274 5 ? 7 HELX_P HELX_P9 AA9 GLU A 278 ? TRP A 294 ? GLU A 278 TRP A 294 1 ? 17 HELX_P HELX_P10 AB1 ASP A 318 ? GLY A 345 ? ASP A 318 GLY A 345 1 ? 28 HELX_P HELX_P11 AB2 GLY A 357 ? ALA A 362 ? GLY A 357 ALA A 362 1 ? 6 HELX_P HELX_P12 AB3 ASN A 365 ? GLN A 370 ? ASN A 365 GLN A 370 1 ? 6 HELX_P HELX_P13 AB4 THR A 410 ? GLN A 421 ? THR A 410 GLN A 421 1 ? 12 HELX_P HELX_P14 AB5 ASP A 424 ? ASN A 426 ? ASP A 424 ASN A 426 5 ? 3 HELX_P HELX_P15 AB6 TYR A 470 ? ASP A 476 ? TYR A 470 ASP A 476 1 ? 7 HELX_P HELX_P16 AB7 LEU A 477 ? TYR A 480 ? LEU A 477 TYR A 480 5 ? 4 HELX_P HELX_P17 AB8 SER A 506 ? ARG A 519 ? SER A 506 ARG A 519 1 ? 14 HELX_P HELX_P18 AB9 GLU A 529 ? ASP A 533 ? GLU A 529 ASP A 533 5 ? 5 HELX_P HELX_P19 AC1 GLY A 535 ? ASN A 542 ? GLY A 535 ASN A 542 1 ? 8 HELX_P HELX_P20 AC2 ALA B 42 ? LEU B 46 ? ALA B 42 LEU B 46 1 ? 5 HELX_P HELX_P21 AC3 TRP B 157 ? TYR B 160 ? TRP B 157 TYR B 160 5 ? 4 HELX_P HELX_P22 AC4 PRO B 165 ? VAL B 169 ? PRO B 165 VAL B 169 5 ? 5 HELX_P HELX_P23 AC5 PRO B 170 ? LEU B 174 ? PRO B 170 LEU B 174 5 ? 5 HELX_P HELX_P24 AC6 ASN B 191 ? ILE B 197 ? ASN B 191 ILE B 197 5 ? 7 HELX_P HELX_P25 AC7 GLY B 199 ? CYS B 208 ? GLY B 199 CYS B 208 1 ? 10 HELX_P HELX_P26 AC8 ASP B 220 ? GLN B 226 ? ASP B 220 GLN B 226 1 ? 7 HELX_P HELX_P27 AC9 LYS B 240 ? ASN B 253 ? LYS B 240 ASN B 253 1 ? 14 HELX_P HELX_P28 AD1 SER B 268 ? MET B 274 ? SER B 268 MET B 274 5 ? 7 HELX_P HELX_P29 AD2 ASP B 276 ? TRP B 294 ? ASP B 276 TRP B 294 1 ? 19 HELX_P HELX_P30 AD3 ASP B 318 ? GLY B 345 ? ASP B 318 GLY B 345 1 ? 28 HELX_P HELX_P31 AD4 GLY B 357 ? ALA B 362 ? GLY B 357 ALA B 362 1 ? 6 HELX_P HELX_P32 AD5 GLU B 368 ? SER B 372 ? GLU B 368 SER B 372 5 ? 5 HELX_P HELX_P33 AD6 THR B 410 ? LYS B 420 ? THR B 410 LYS B 420 1 ? 11 HELX_P HELX_P34 AD7 TYR B 470 ? ASP B 476 ? TYR B 470 ASP B 476 1 ? 7 HELX_P HELX_P35 AD8 LEU B 477 ? TYR B 480 ? LEU B 477 TYR B 480 5 ? 4 HELX_P HELX_P36 AD9 SER B 506 ? ASN B 520 ? SER B 506 ASN B 520 1 ? 15 HELX_P HELX_P37 AE1 GLU B 529 ? ASP B 533 ? GLU B 529 ASP B 533 5 ? 5 HELX_P HELX_P38 AE2 GLY B 535 ? ASN B 542 ? GLY B 535 ASN B 542 1 ? 8 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 106 SG ? ? ? 1_555 A CYS 111 SG ? ? A CYS 106 A CYS 111 1_555 ? ? ? ? ? ? ? 2.032 ? disulf2 disulf ? ? A CYS 185 SG ? ? ? 1_555 A CYS 208 SG ? ? A CYS 185 A CYS 208 1_555 ? ? ? ? ? ? ? 2.032 ? disulf3 disulf ? ? B CYS 106 SG ? ? ? 1_555 B CYS 111 SG ? ? B CYS 106 B CYS 111 1_555 ? ? ? ? ? ? ? 2.031 ? disulf4 disulf ? ? B CYS 185 SG ? ? ? 1_555 B CYS 208 SG ? ? B CYS 185 B CYS 208 1_555 ? ? ? ? ? ? ? 2.033 ? covale1 covale one ? B ASN 444 ND2 ? ? ? 1_555 N NAG . C1 ? ? B ASN 444 B NAG 603 1_555 ? ? ? ? ? ? ? 1.446 ? covale2 covale one ? F SN5 . C1 ? ? ? 1_555 G 58Y . O4 ? ? A SN5 604 A 58Y 605 1_555 ? ? ? ? ? ? ? 1.444 ? covale3 covale one ? O SN5 . C1 ? ? ? 1_555 P 58Y . O4 ? ? B SN5 604 B 58Y 605 1_555 ? ? ? ? ? ? ? 1.444 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PRO 142 A . ? PRO 142 A GLY 143 A ? GLY 143 A 1 1.88 2 GLY 180 A . ? GLY 180 A PHE 181 A ? PHE 181 A 1 0.46 3 GLU 305 A . ? GLU 305 A PHE 306 A ? PHE 306 A 1 -2.71 4 TRP 528 A . ? TRP 528 A GLU 529 A ? GLU 529 A 1 -3.95 5 GLY 180 B . ? GLY 180 B PHE 181 B ? PHE 181 B 1 0.94 6 GLU 305 B . ? GLU 305 B PHE 306 B ? PHE 306 B 1 -3.84 7 TRP 528 B . ? TRP 528 B GLU 529 B ? GLU 529 B 1 -2.42 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 3 ? AA2 ? 5 ? AA3 ? 4 ? AA4 ? 2 ? AA5 ? 9 ? AA6 ? 5 ? AA7 ? 3 ? AA8 ? 5 ? AA9 ? 4 ? AB1 ? 2 ? AB2 ? 9 ? AB3 ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? anti-parallel AA2 1 2 ? parallel AA2 2 3 ? anti-parallel AA2 3 4 ? anti-parallel AA2 4 5 ? anti-parallel AA3 1 2 ? parallel AA3 2 3 ? anti-parallel AA3 3 4 ? anti-parallel AA4 1 2 ? anti-parallel AA5 1 2 ? parallel AA5 2 3 ? parallel AA5 3 4 ? parallel AA5 4 5 ? parallel AA5 5 6 ? parallel AA5 6 7 ? parallel AA5 7 8 ? parallel AA5 8 9 ? parallel AA6 1 2 ? anti-parallel AA6 2 3 ? anti-parallel AA6 3 4 ? anti-parallel AA6 4 5 ? anti-parallel AA7 1 2 ? anti-parallel AA7 2 3 ? anti-parallel AA8 1 2 ? parallel AA8 2 3 ? anti-parallel AA8 3 4 ? anti-parallel AA8 4 5 ? anti-parallel AA9 1 2 ? parallel AA9 2 3 ? anti-parallel AA9 3 4 ? anti-parallel AB1 1 2 ? anti-parallel AB2 1 2 ? parallel AB2 2 3 ? parallel AB2 3 4 ? parallel AB2 4 5 ? parallel AB2 5 6 ? parallel AB2 6 7 ? parallel AB2 7 8 ? parallel AB2 8 9 ? parallel AB3 1 2 ? anti-parallel AB3 2 3 ? anti-parallel AB3 3 4 ? anti-parallel AB3 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 THR A 21 ? ILE A 24 ? THR A 21 ILE A 24 AA1 2 VAL A 53 ? TRP A 62 ? VAL A 53 TRP A 62 AA1 3 ARG A 88 ? VAL A 93 ? ARG A 88 VAL A 93 AA2 1 ASN A 30 ? ALA A 32 ? ASN A 30 ALA A 32 AA2 2 VAL A 117 ? ALA A 122 ? VAL A 117 ALA A 122 AA2 3 GLY A 97 ? CYS A 106 ? GLY A 97 CYS A 106 AA2 4 ILE A 69 ? LEU A 73 ? ILE A 69 LEU A 73 AA2 5 GLN A 78 ? ASP A 83 ? GLN A 78 ASP A 83 AA3 1 ASN A 30 ? ALA A 32 ? ASN A 30 ALA A 32 AA3 2 VAL A 117 ? ALA A 122 ? VAL A 117 ALA A 122 AA3 3 GLY A 97 ? CYS A 106 ? GLY A 97 CYS A 106 AA3 4 CYS A 111 ? VAL A 113 ? CYS A 111 VAL A 113 AA4 1 VAL A 34 ? ILE A 36 ? VAL A 34 ILE A 36 AA4 2 ILE A 47 ? PRO A 49 ? ILE A 47 PRO A 49 AA5 1 ILE A 149 ? VAL A 155 ? ILE A 149 VAL A 155 AA5 2 HIS A 176 ? ILE A 182 ? HIS A 176 ILE A 182 AA5 3 LYS A 257 ? GLY A 263 ? LYS A 257 GLY A 263 AA5 4 GLY A 299 ? ASP A 303 ? GLY A 299 ASP A 303 AA5 5 GLU A 349 ? SER A 355 ? GLU A 349 SER A 355 AA5 6 LYS A 375 ? MET A 379 ? LYS A 375 MET A 379 AA5 7 ILE A 428 ? ALA A 433 ? ILE A 428 ALA A 433 AA5 8 GLY A 524 ? TRP A 528 ? GLY A 524 TRP A 528 AA5 9 ILE A 149 ? VAL A 155 ? ILE A 149 VAL A 155 AA6 1 VAL A 467 ? ASP A 469 ? VAL A 467 ASP A 469 AA6 2 TYR A 435 ? TRP A 439 ? TYR A 435 TRP A 439 AA6 3 ASP A 500 ? PHE A 504 ? ASP A 500 PHE A 504 AA6 4 ALA A 490 ? ASP A 495 ? ALA A 490 ASP A 495 AA6 5 VAL A 481 ? ASP A 485 ? VAL A 481 ASP A 485 AA7 1 THR B 21 ? ILE B 24 ? THR B 21 ILE B 24 AA7 2 VAL B 53 ? TRP B 62 ? VAL B 53 TRP B 62 AA7 3 ARG B 88 ? VAL B 93 ? ARG B 88 VAL B 93 AA8 1 ASN B 30 ? ALA B 32 ? ASN B 30 ALA B 32 AA8 2 VAL B 117 ? ALA B 122 ? VAL B 117 ALA B 122 AA8 3 GLY B 97 ? CYS B 106 ? GLY B 97 CYS B 106 AA8 4 ILE B 69 ? PHE B 74 ? ILE B 69 PHE B 74 AA8 5 GLN B 77 ? GLY B 82 ? GLN B 77 GLY B 82 AA9 1 ASN B 30 ? ALA B 32 ? ASN B 30 ALA B 32 AA9 2 VAL B 117 ? ALA B 122 ? VAL B 117 ALA B 122 AA9 3 GLY B 97 ? CYS B 106 ? GLY B 97 CYS B 106 AA9 4 CYS B 111 ? VAL B 113 ? CYS B 111 VAL B 113 AB1 1 VAL B 34 ? ILE B 36 ? VAL B 34 ILE B 36 AB1 2 ILE B 47 ? PRO B 49 ? ILE B 47 PRO B 49 AB2 1 ILE B 149 ? VAL B 155 ? ILE B 149 VAL B 155 AB2 2 HIS B 176 ? ILE B 182 ? HIS B 176 ILE B 182 AB2 3 LYS B 257 ? GLY B 264 ? LYS B 257 GLY B 264 AB2 4 GLY B 299 ? TRP B 304 ? GLY B 299 TRP B 304 AB2 5 GLU B 349 ? SER B 355 ? GLU B 349 SER B 355 AB2 6 LYS B 375 ? MET B 379 ? LYS B 375 MET B 379 AB2 7 ILE B 428 ? ALA B 433 ? ILE B 428 ALA B 433 AB2 8 GLY B 524 ? TRP B 528 ? GLY B 524 TRP B 528 AB2 9 ILE B 149 ? VAL B 155 ? ILE B 149 VAL B 155 AB3 1 VAL B 467 ? ASP B 469 ? VAL B 467 ASP B 469 AB3 2 TYR B 435 ? TRP B 439 ? TYR B 435 TRP B 439 AB3 3 ASP B 500 ? PHE B 504 ? ASP B 500 PHE B 504 AB3 4 ALA B 490 ? ASP B 495 ? ALA B 490 ASP B 495 AB3 5 VAL B 481 ? ASP B 485 ? VAL B 481 ASP B 485 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N VAL A 23 ? N VAL A 23 O ASN A 60 ? O ASN A 60 AA1 2 3 N VAL A 55 ? N VAL A 55 O ILE A 91 ? O ILE A 91 AA2 1 2 N TYR A 31 ? N TYR A 31 O LYS A 120 ? O LYS A 120 AA2 2 3 O VAL A 117 ? O VAL A 117 N MET A 101 ? N MET A 101 AA2 3 4 O CYS A 106 ? O CYS A 106 N ILE A 69 ? N ILE A 69 AA2 4 5 N VAL A 72 ? N VAL A 72 O VAL A 79 ? O VAL A 79 AA3 1 2 N TYR A 31 ? N TYR A 31 O LYS A 120 ? O LYS A 120 AA3 2 3 O VAL A 117 ? O VAL A 117 N MET A 101 ? N MET A 101 AA3 3 4 N LEU A 105 ? N LEU A 105 O SER A 112 ? O SER A 112 AA4 1 2 N GLU A 35 ? N GLU A 35 O LYS A 48 ? O LYS A 48 AA5 1 2 N PHE A 154 ? N PHE A 154 O LEU A 178 ? O LEU A 178 AA5 2 3 N ILE A 182 ? N ILE A 182 O SER A 261 ? O SER A 261 AA5 3 4 N ILE A 262 ? N ILE A 262 O ASP A 301 ? O ASP A 301 AA5 4 5 N VAL A 300 ? N VAL A 300 O GLU A 349 ? O GLU A 349 AA5 5 6 N ILE A 354 ? N ILE A 354 O MET A 379 ? O MET A 379 AA5 6 7 N LEU A 378 ? N LEU A 378 O ILE A 429 ? O ILE A 429 AA5 7 8 N VAL A 432 ? N VAL A 432 O PHE A 526 ? O PHE A 526 AA5 8 9 O LEU A 525 ? O LEU A 525 N ILE A 149 ? N ILE A 149 AA6 1 2 O VAL A 468 ? O VAL A 468 N GLY A 436 ? N GLY A 436 AA6 2 3 N ARG A 437 ? N ARG A 437 O SER A 503 ? O SER A 503 AA6 3 4 O ILE A 502 ? O ILE A 502 N VAL A 493 ? N VAL A 493 AA6 4 5 O ALA A 490 ? O ALA A 490 N ASP A 485 ? N ASP A 485 AA7 1 2 N VAL B 23 ? N VAL B 23 O ASN B 60 ? O ASN B 60 AA7 2 3 N VAL B 53 ? N VAL B 53 O VAL B 93 ? O VAL B 93 AA8 1 2 N TYR B 31 ? N TYR B 31 O LYS B 120 ? O LYS B 120 AA8 2 3 O VAL B 119 ? O VAL B 119 N PHE B 99 ? N PHE B 99 AA8 3 4 O LYS B 104 ? O LYS B 104 N TYR B 71 ? N TYR B 71 AA8 4 5 N ALA B 70 ? N ALA B 70 O GLY B 82 ? O GLY B 82 AA9 1 2 N TYR B 31 ? N TYR B 31 O LYS B 120 ? O LYS B 120 AA9 2 3 O VAL B 119 ? O VAL B 119 N PHE B 99 ? N PHE B 99 AA9 3 4 N LEU B 105 ? N LEU B 105 O SER B 112 ? O SER B 112 AB1 1 2 N GLU B 35 ? N GLU B 35 O LYS B 48 ? O LYS B 48 AB2 1 2 N ALA B 152 ? N ALA B 152 O LEU B 178 ? O LEU B 178 AB2 2 3 N ILE B 182 ? N ILE B 182 O SER B 261 ? O SER B 261 AB2 3 4 N ILE B 262 ? N ILE B 262 O ASP B 301 ? O ASP B 301 AB2 4 5 N VAL B 300 ? N VAL B 300 O THR B 351 ? O THR B 351 AB2 5 6 N ILE B 354 ? N ILE B 354 O MET B 379 ? O MET B 379 AB2 6 7 N ILE B 376 ? N ILE B 376 O ILE B 429 ? O ILE B 429 AB2 7 8 N VAL B 432 ? N VAL B 432 O PHE B 526 ? O PHE B 526 AB2 8 9 O LEU B 525 ? O LEU B 525 N ILE B 149 ? N ILE B 149 AB3 1 2 O VAL B 468 ? O VAL B 468 N GLY B 436 ? N GLY B 436 AB3 2 3 N ARG B 437 ? N ARG B 437 O SER B 503 ? O SER B 503 AB3 3 4 O ILE B 502 ? O ILE B 502 N VAL B 493 ? N VAL B 493 AB3 4 5 O ALA B 490 ? O ALA B 490 N ASP B 485 ? N ASP B 485 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A NAG 601 ? 5 'binding site for residue NAG A 601' AC2 Software A NAG 602 ? 8 'binding site for residue NAG A 602' AC3 Software A NAG 603 ? 6 'binding site for residue NAG A 603' AC4 Software A CL 606 ? 1 'binding site for residue CL A 606' AC5 Software A SO4 607 ? 2 'binding site for residue SO4 A 607' AC6 Software A SO4 608 ? 3 'binding site for residue SO4 A 608' AC7 Software A SO4 609 ? 3 'binding site for residue SO4 A 609' AC8 Software B NAG 601 ? 5 'binding site for residue NAG B 601' AC9 Software B NAG 602 ? 7 'binding site for residue NAG B 602' AD1 Software B SO4 606 ? 2 'binding site for residue SO4 B 606' AD2 Software B SO4 607 ? 3 'binding site for residue SO4 B 607' AD3 Software B NAG 603 ? 2 'binding site for Mono-Saccharide NAG B 603 bound to ASN B 444' AD4 Software A SN5 604 ? 15 'binding site for residues SN5 A 604 and 58Y A 605' AD5 Software B SN5 604 ? 14 'binding site for residues SN5 B 604 and 58Y B 605' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 5 ASP A 125 ? ASP A 125 . ? 1_555 ? 2 AC1 5 LYS A 250 ? LYS A 250 . ? 1_555 ? 3 AC1 5 LYS A 295 ? LYS A 295 . ? 1_555 ? 4 AC1 5 ASP A 298 ? ASP A 298 . ? 1_555 ? 5 AC1 5 ARG A 346 ? ARG A 346 . ? 1_555 ? 6 AC2 8 TRP A 26 ? TRP A 26 . ? 1_555 ? 7 AC2 8 ASP A 28 ? ASP A 28 . ? 1_555 ? 8 AC2 8 ARG A 29 ? ARG A 29 . ? 1_555 ? 9 AC2 8 ASN A 30 ? ASN A 30 . ? 1_555 ? 10 AC2 8 TRP A 235 ? TRP A 235 . ? 1_555 ? 11 AC2 8 ASN A 236 ? ASN A 236 . ? 1_555 ? 12 AC2 8 GLU B 133 ? GLU B 133 . ? 1_555 ? 13 AC2 8 TRP B 136 ? TRP B 136 . ? 1_555 ? 14 AC3 6 TRP A 265 ? TRP A 265 . ? 1_555 ? 15 AC3 6 ASP A 382 ? ASP A 382 . ? 1_555 ? 16 AC3 6 TRP A 387 ? TRP A 387 . ? 1_555 ? 17 AC3 6 ARG A 437 ? ARG A 437 . ? 1_555 ? 18 AC3 6 SN5 F . ? SN5 A 604 . ? 1_555 ? 19 AC3 6 58Y G . ? 58Y A 605 . ? 1_555 ? 20 AC4 1 VAL A 53 ? VAL A 53 . ? 1_555 ? 21 AC5 2 PRO A 49 ? PRO A 49 . ? 1_555 ? 22 AC5 2 GLU A 289 ? GLU A 289 . ? 1_555 ? 23 AC6 3 ARG A 211 ? ARG A 211 . ? 1_555 ? 24 AC6 3 LYS A 215 ? LYS A 215 . ? 1_555 ? 25 AC6 3 GLU A 289 ? GLU A 289 . ? 1_555 ? 26 AC7 3 TRP A 80 ? TRP A 80 . ? 1_555 ? 27 AC7 3 ALA A 89 ? ALA A 89 . ? 1_555 ? 28 AC7 3 THR A 90 ? THR A 90 . ? 1_555 ? 29 AC8 5 ASP B 382 ? ASP B 382 . ? 1_555 ? 30 AC8 5 TRP B 387 ? TRP B 387 . ? 1_555 ? 31 AC8 5 ARG B 437 ? ARG B 437 . ? 1_555 ? 32 AC8 5 SN5 O . ? SN5 B 604 . ? 1_555 ? 33 AC8 5 58Y P . ? 58Y B 605 . ? 1_555 ? 34 AC9 7 TYR B 358 ? TYR B 358 . ? 1_555 ? 35 AC9 7 PHE B 383 ? PHE B 383 . ? 1_555 ? 36 AC9 7 LYS B 384 ? LYS B 384 . ? 1_555 ? 37 AC9 7 ASP B 391 ? ASP B 391 . ? 1_555 ? 38 AC9 7 GLU B 407 ? GLU B 407 . ? 1_555 ? 39 AC9 7 LEU B 408 ? LEU B 408 . ? 1_555 ? 40 AC9 7 TYR B 409 ? TYR B 409 . ? 1_555 ? 41 AD1 2 LYS B 168 ? LYS B 168 . ? 1_555 ? 42 AD1 2 ARG B 471 ? ARG B 471 . ? 1_555 ? 43 AD2 3 ARG B 211 ? ARG B 211 . ? 1_555 ? 44 AD2 3 SER B 286 ? SER B 286 . ? 1_555 ? 45 AD2 3 GLU B 289 ? GLU B 289 . ? 1_555 ? 46 AD3 2 ASN B 444 ? ASN B 444 . ? 1_555 ? 47 AD3 2 THR B 454 ? THR B 454 . ? 1_555 ? 48 AD4 15 TYR A 153 ? TYR A 153 . ? 1_555 ? 49 AD4 15 PHE A 181 ? PHE A 181 . ? 1_555 ? 50 AD4 15 ILE A 197 ? ILE A 197 . ? 1_555 ? 51 AD4 15 TRP A 265 ? TRP A 265 . ? 1_555 ? 52 AD4 15 THR A 266 ? THR A 266 . ? 1_555 ? 53 AD4 15 GLU A 305 ? GLU A 305 . ? 1_555 ? 54 AD4 15 MET A 379 ? MET A 379 . ? 1_555 ? 55 AD4 15 TYR A 381 ? TYR A 381 . ? 1_555 ? 56 AD4 15 ASP A 382 ? ASP A 382 . ? 1_555 ? 57 AD4 15 TYR A 435 ? TYR A 435 . ? 1_555 ? 58 AD4 15 ARG A 437 ? ARG A 437 . ? 1_555 ? 59 AD4 15 VAL A 467 ? VAL A 467 . ? 1_555 ? 60 AD4 15 TRP A 528 ? TRP A 528 . ? 1_555 ? 61 AD4 15 GLU A 529 ? GLU A 529 . ? 1_555 ? 62 AD4 15 NAG E . ? NAG A 603 . ? 1_555 ? 63 AD5 14 TYR B 153 ? TYR B 153 . ? 1_555 ? 64 AD5 14 PHE B 181 ? PHE B 181 . ? 1_555 ? 65 AD5 14 ILE B 197 ? ILE B 197 . ? 1_555 ? 66 AD5 14 TRP B 265 ? TRP B 265 . ? 1_555 ? 67 AD5 14 THR B 266 ? THR B 266 . ? 1_555 ? 68 AD5 14 GLU B 305 ? GLU B 305 . ? 1_555 ? 69 AD5 14 MET B 379 ? MET B 379 . ? 1_555 ? 70 AD5 14 TYR B 381 ? TYR B 381 . ? 1_555 ? 71 AD5 14 ASP B 382 ? ASP B 382 . ? 1_555 ? 72 AD5 14 TYR B 435 ? TYR B 435 . ? 1_555 ? 73 AD5 14 VAL B 467 ? VAL B 467 . ? 1_555 ? 74 AD5 14 TRP B 528 ? TRP B 528 . ? 1_555 ? 75 AD5 14 GLU B 529 ? GLU B 529 . ? 1_555 ? 76 AD5 14 NAG L . ? NAG B 601 . ? 1_555 ? # _atom_sites.entry_id 5DF0 _atom_sites.fract_transf_matrix[1][1] 0.010340 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.008868 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007717 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CL N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ILE A 1 18 ? -51.220 24.389 263.866 1.00 43.39 ? 18 ILE A N 1 ATOM 2 C CA . ILE A 1 18 ? -52.404 24.532 264.701 1.00 37.86 ? 18 ILE A CA 1 ATOM 3 C C . ILE A 1 18 ? -51.990 24.737 266.154 1.00 34.44 ? 18 ILE A C 1 ATOM 4 O O . ILE A 1 18 ? -50.905 24.315 266.556 1.00 40.50 ? 18 ILE A O 1 ATOM 5 C CB . ILE A 1 18 ? -53.338 23.312 264.559 1.00 42.40 ? 18 ILE A CB 1 ATOM 6 C CG1 . ILE A 1 18 ? -52.687 22.063 265.157 1.00 59.57 ? 18 ILE A CG1 1 ATOM 7 C CG2 . ILE A 1 18 ? -53.696 23.084 263.099 1.00 51.39 ? 18 ILE A CG2 1 ATOM 8 C CD1 . ILE A 1 18 ? -53.643 20.905 265.338 1.00 42.57 ? 18 ILE A CD1 1 ATOM 9 N N . PRO A 1 19 ? -52.840 25.392 266.940 1.00 34.79 ? 19 PRO A N 1 ATOM 10 C CA . PRO A 1 19 ? -52.556 25.540 268.370 1.00 35.76 ? 19 PRO A CA 1 ATOM 11 C C . PRO A 1 19 ? -52.577 24.192 269.073 1.00 37.81 ? 19 PRO A C 1 ATOM 12 O O . PRO A 1 19 ? -52.893 23.151 268.494 1.00 38.61 ? 19 PRO A O 1 ATOM 13 C CB . PRO A 1 19 ? -53.681 26.449 268.877 1.00 39.30 ? 19 PRO A CB 1 ATOM 14 C CG . PRO A 1 19 ? -54.244 27.094 267.659 1.00 50.02 ? 19 PRO A CG 1 ATOM 15 C CD . PRO A 1 19 ? -54.064 26.110 266.547 1.00 46.43 ? 19 PRO A CD 1 ATOM 16 N N . GLY A 1 20 ? -52.231 24.229 270.356 1.00 41.97 ? 20 GLY A N 1 ATOM 17 C CA . GLY A 1 20 ? -52.221 23.010 271.140 1.00 39.64 ? 20 GLY A CA 1 ATOM 18 C C . GLY A 1 20 ? -53.610 22.422 271.290 1.00 36.51 ? 20 GLY A C 1 ATOM 19 O O . GLY A 1 20 ? -54.622 23.122 271.219 1.00 37.76 ? 20 GLY A O 1 ATOM 20 N N . THR A 1 21 ? -53.654 21.114 271.489 1.00 37.80 ? 21 THR A N 1 ATOM 21 C CA . THR A 1 21 ? -54.926 20.443 271.719 1.00 32.01 ? 21 THR A CA 1 ATOM 22 C C . THR A 1 21 ? -55.461 20.823 273.094 1.00 32.59 ? 21 THR A C 1 ATOM 23 O O . THR A 1 21 ? -54.756 20.645 274.097 1.00 34.56 ? 21 THR A O 1 ATOM 24 C CB . THR A 1 21 ? -54.773 18.926 271.593 1.00 34.01 ? 21 THR A CB 1 ATOM 25 O OG1 . THR A 1 21 ? -55.956 18.279 272.078 1.00 34.08 ? 21 THR A OG1 1 ATOM 26 C CG2 . THR A 1 21 ? -53.556 18.421 272.362 1.00 46.75 ? 21 THR A CG2 1 ATOM 27 N N . PRO A 1 22 ? -56.670 21.362 273.192 1.00 30.88 ? 22 PRO A N 1 ATOM 28 C CA . PRO A 1 22 ? -57.203 21.739 274.502 1.00 29.81 ? 22 PRO A CA 1 ATOM 29 C C . PRO A 1 22 ? -57.830 20.553 275.214 1.00 27.75 ? 22 PRO A C 1 ATOM 30 O O . PRO A 1 22 ? -58.399 19.650 274.597 1.00 25.27 ? 22 PRO A O 1 ATOM 31 C CB . PRO A 1 22 ? -58.252 22.806 274.162 1.00 27.18 ? 22 PRO A CB 1 ATOM 32 C CG . PRO A 1 22 ? -58.596 22.586 272.700 1.00 26.53 ? 22 PRO A CG 1 ATOM 33 C CD . PRO A 1 22 ? -57.650 21.572 272.115 1.00 27.96 ? 22 PRO A CD 1 ATOM 34 N N . VAL A 1 23 ? -57.703 20.560 276.538 1.00 27.49 ? 23 VAL A N 1 ATOM 35 C CA . VAL A 1 23 ? -58.239 19.503 277.387 1.00 26.59 ? 23 VAL A CA 1 ATOM 36 C C . VAL A 1 23 ? -59.085 20.162 278.465 1.00 25.33 ? 23 VAL A C 1 ATOM 37 O O . VAL A 1 23 ? -58.548 20.806 279.374 1.00 24.69 ? 23 VAL A O 1 ATOM 38 C CB . VAL A 1 23 ? -57.140 18.640 278.016 1.00 27.57 ? 23 VAL A CB 1 ATOM 39 C CG1 . VAL A 1 23 ? -57.762 17.619 278.950 1.00 32.39 ? 23 VAL A CG1 1 ATOM 40 C CG2 . VAL A 1 23 ? -56.319 17.954 276.935 1.00 32.97 ? 23 VAL A CG2 1 ATOM 41 N N . ILE A 1 24 ? -60.403 19.990 278.374 1.00 26.16 ? 24 ILE A N 1 ATOM 42 C CA . ILE A 1 24 ? -61.312 20.596 279.337 1.00 28.02 ? 24 ILE A CA 1 ATOM 43 C C . ILE A 1 24 ? -61.128 19.934 280.695 1.00 26.46 ? 24 ILE A C 1 ATOM 44 O O . ILE A 1 24 ? -61.209 18.705 280.822 1.00 25.87 ? 24 ILE A O 1 ATOM 45 C CB . ILE A 1 24 ? -62.762 20.477 278.848 1.00 29.08 ? 24 ILE A CB 1 ATOM 46 C CG1 . ILE A 1 24 ? -62.911 21.120 277.469 1.00 29.17 ? 24 ILE A CG1 1 ATOM 47 C CG2 . ILE A 1 24 ? -63.708 21.128 279.833 1.00 28.39 ? 24 ILE A CG2 1 ATOM 48 C CD1 . ILE A 1 24 ? -64.321 21.086 276.929 1.00 22.57 ? 24 ILE A CD1 1 ATOM 49 N N . ASP A 1 25 ? -60.876 20.746 281.718 1.00 24.60 ? 25 ASP A N 1 ATOM 50 C CA . ASP A 1 25 ? -60.696 20.224 283.064 1.00 26.77 ? 25 ASP A CA 1 ATOM 51 C C . ASP A 1 25 ? -61.994 19.614 283.581 1.00 30.29 ? 25 ASP A C 1 ATOM 52 O O . ASP A 1 25 ? -63.094 20.019 283.199 1.00 32.81 ? 25 ASP A O 1 ATOM 53 C CB . ASP A 1 25 ? -60.228 21.329 284.009 1.00 31.02 ? 25 ASP A CB 1 ATOM 54 C CG . ASP A 1 25 ? -58.989 22.040 283.505 1.00 51.07 ? 25 ASP A CG 1 ATOM 55 O OD1 . ASP A 1 25 ? -58.224 21.427 282.731 1.00 51.58 ? 25 ASP A OD1 1 ATOM 56 O OD2 . ASP A 1 25 ? -58.779 23.211 283.884 1.00 37.85 ? 25 ASP A OD2 1 ATOM 57 N N . TRP A 1 26 ? -61.855 18.627 284.462 1.00 32.33 ? 26 TRP A N 1 ATOM 58 C CA . TRP A 1 26 ? -63.014 17.926 284.991 1.00 28.46 ? 26 TRP A CA 1 ATOM 59 C C . TRP A 1 26 ? -63.696 18.749 286.074 1.00 30.69 ? 26 TRP A C 1 ATOM 60 O O . TRP A 1 26 ? -63.039 19.342 286.934 1.00 30.19 ? 26 TRP A O 1 ATOM 61 C CB . TRP A 1 26 ? -62.615 16.562 285.555 1.00 29.18 ? 26 TRP A CB 1 ATOM 62 C CG . TRP A 1 26 ? -63.792 15.770 286.037 1.00 28.76 ? 26 TRP A CG 1 ATOM 63 C CD1 . TRP A 1 26 ? -64.538 14.887 285.312 1.00 30.65 ? 26 TRP A CD1 1 ATOM 64 C CD2 . TRP A 1 26 ? -64.372 15.802 287.347 1.00 32.94 ? 26 TRP A CD2 1 ATOM 65 N NE1 . TRP A 1 26 ? -65.540 14.362 286.090 1.00 38.20 ? 26 TRP A NE1 1 ATOM 66 C CE2 . TRP A 1 26 ? -65.461 14.908 287.344 1.00 36.59 ? 26 TRP A CE2 1 ATOM 67 C CE3 . TRP A 1 26 ? -64.074 16.498 288.523 1.00 35.97 ? 26 TRP A CE3 1 ATOM 68 C CZ2 . TRP A 1 26 ? -66.252 14.692 288.471 1.00 38.92 ? 26 TRP A CZ2 1 ATOM 69 C CZ3 . TRP A 1 26 ? -64.861 16.281 289.640 1.00 46.58 ? 26 TRP A CZ3 1 ATOM 70 C CH2 . TRP A 1 26 ? -65.937 15.386 289.606 1.00 42.97 ? 26 TRP A CH2 1 ATOM 71 N N . ALA A 1 27 ? -65.024 18.771 286.027 1.00 35.60 ? 27 ALA A N 1 ATOM 72 C CA . ALA A 1 27 ? -65.851 19.450 287.016 1.00 35.03 ? 27 ALA A CA 1 ATOM 73 C C . ALA A 1 27 ? -67.285 18.984 286.812 1.00 33.95 ? 27 ALA A C 1 ATOM 74 O O . ALA A 1 27 ? -67.622 18.387 285.786 1.00 33.23 ? 27 ALA A O 1 ATOM 75 C CB . ALA A 1 27 ? -65.746 20.973 286.900 1.00 36.03 ? 27 ALA A CB 1 ATOM 76 N N . ASP A 1 28 ? -68.127 19.260 287.804 1.00 36.63 ? 28 ASP A N 1 ATOM 77 C CA . ASP A 1 28 ? -69.541 18.929 287.691 1.00 40.67 ? 28 ASP A CA 1 ATOM 78 C C . ASP A 1 28 ? -70.222 19.904 286.741 1.00 37.93 ? 28 ASP A C 1 ATOM 79 O O . ASP A 1 28 ? -70.234 21.115 286.985 1.00 63.40 ? 28 ASP A O 1 ATOM 80 C CB . ASP A 1 28 ? -70.216 18.961 289.059 1.00 49.01 ? 28 ASP A CB 1 ATOM 81 C CG . ASP A 1 28 ? -71.730 18.973 288.955 1.00 54.62 ? 28 ASP A CG 1 ATOM 82 O OD1 . ASP A 1 28 ? -72.291 18.039 288.345 1.00 72.82 ? 28 ASP A OD1 1 ATOM 83 O OD2 . ASP A 1 28 ? -72.358 19.916 289.481 1.00 45.44 ? 28 ASP A OD2 1 ATOM 84 N N . ARG A 1 29 ? -70.792 19.378 285.660 1.00 35.33 ? 29 ARG A N 1 ATOM 85 C CA . ARG A 1 29 ? -71.490 20.185 284.670 1.00 31.85 ? 29 ARG A CA 1 ATOM 86 C C . ARG A 1 29 ? -72.978 19.857 284.623 1.00 32.03 ? 29 ARG A C 1 ATOM 87 O O . ARG A 1 29 ? -73.618 19.970 283.575 1.00 29.62 ? 29 ARG A O 1 ATOM 88 C CB . ARG A 1 29 ? -70.835 20.015 283.301 1.00 28.23 ? 29 ARG A CB 1 ATOM 89 C CG . ARG A 1 29 ? -69.474 20.682 283.255 1.00 33.22 ? 29 ARG A CG 1 ATOM 90 C CD . ARG A 1 29 ? -68.640 20.287 282.057 1.00 37.13 ? 29 ARG A CD 1 ATOM 91 N NE . ARG A 1 29 ? -67.387 21.035 282.061 1.00 44.25 ? 29 ARG A NE 1 ATOM 92 C CZ . ARG A 1 29 ? -66.290 20.647 282.703 1.00 45.34 ? 29 ARG A CZ 1 ATOM 93 N NH1 . ARG A 1 29 ? -66.289 19.512 283.388 1.00 49.01 ? 29 ARG A NH1 1 ATOM 94 N NH2 . ARG A 1 29 ? -65.196 21.394 282.663 1.00 31.67 ? 29 ARG A NH2 1 ATOM 95 N N . ASN A 1 30 ? -73.533 19.448 285.761 1.00 33.22 ? 30 ASN A N 1 ATOM 96 C CA . ASN A 1 30 ? -74.971 19.270 285.931 1.00 33.00 ? 30 ASN A CA 1 ATOM 97 C C . ASN A 1 30 ? -75.502 20.534 286.595 1.00 35.35 ? 30 ASN A C 1 ATOM 98 O O . ASN A 1 30 ? -75.308 20.747 287.795 1.00 29.36 ? 30 ASN A O 1 ATOM 99 C CB . ASN A 1 30 ? -75.276 18.028 286.761 1.00 41.53 ? 30 ASN A CB 1 ATOM 100 C CG . ASN A 1 30 ? -74.877 16.747 286.059 1.00 45.07 ? 30 ASN A CG 1 ATOM 101 O OD1 . ASN A 1 30 ? -73.915 16.720 285.293 1.00 44.97 ? 30 ASN A OD1 1 ATOM 102 N ND2 . ASN A 1 30 ? -75.618 15.676 286.316 1.00 57.74 ? 30 ASN A ND2 1 ATOM 103 N N . TYR A 1 31 ? -76.163 21.377 285.810 1.00 31.66 ? 31 TYR A N 1 ATOM 104 C CA . TYR A 1 31 ? -76.662 22.658 286.280 1.00 30.24 ? 31 TYR A CA 1 ATOM 105 C C . TYR A 1 31 ? -78.182 22.633 286.370 1.00 26.89 ? 31 TYR A C 1 ATOM 106 O O . TYR A 1 31 ? -78.854 21.830 285.717 1.00 26.37 ? 31 TYR A O 1 ATOM 107 C CB . TYR A 1 31 ? -76.205 23.791 285.357 1.00 39.36 ? 31 TYR A CB 1 ATOM 108 C CG . TYR A 1 31 ? -74.707 23.996 285.343 1.00 23.57 ? 31 TYR A CG 1 ATOM 109 C CD1 . TYR A 1 31 ? -74.042 24.474 286.464 1.00 23.23 ? 31 TYR A CD1 1 ATOM 110 C CD2 . TYR A 1 31 ? -73.958 23.713 284.209 1.00 23.60 ? 31 TYR A CD2 1 ATOM 111 C CE1 . TYR A 1 31 ? -72.674 24.664 286.457 1.00 23.87 ? 31 TYR A CE1 1 ATOM 112 C CE2 . TYR A 1 31 ? -72.590 23.899 284.192 1.00 23.93 ? 31 TYR A CE2 1 ATOM 113 C CZ . TYR A 1 31 ? -71.953 24.375 285.319 1.00 23.28 ? 31 TYR A CZ 1 ATOM 114 O OH . TYR A 1 31 ? -70.590 24.561 285.307 1.00 22.69 ? 31 TYR A OH 1 ATOM 115 N N . ALA A 1 32 ? -78.720 23.529 287.194 1.00 26.67 ? 32 ALA A N 1 ATOM 116 C CA . ALA A 1 32 ? -80.156 23.599 287.426 1.00 28.28 ? 32 ALA A CA 1 ATOM 117 C C . ALA A 1 32 ? -80.587 25.053 287.524 1.00 23.51 ? 32 ALA A C 1 ATOM 118 O O . ALA A 1 32 ? -79.995 25.827 288.282 1.00 25.12 ? 32 ALA A O 1 ATOM 119 C CB . ALA A 1 32 ? -80.546 22.847 288.703 1.00 39.71 ? 32 ALA A CB 1 ATOM 120 N N . LEU A 1 33 ? -81.621 25.420 286.763 1.00 25.50 ? 33 LEU A N 1 ATOM 121 C CA . LEU A 1 33 ? -82.158 26.773 286.842 1.00 25.74 ? 33 LEU A CA 1 ATOM 122 C C . LEU A 1 33 ? -82.950 27.003 288.121 1.00 31.56 ? 33 LEU A C 1 ATOM 123 O O . LEU A 1 33 ? -83.205 28.159 288.476 1.00 37.91 ? 33 LEU A O 1 ATOM 124 C CB . LEU A 1 33 ? -83.035 27.062 285.623 1.00 25.53 ? 33 LEU A CB 1 ATOM 125 C CG . LEU A 1 33 ? -82.290 27.253 284.301 1.00 23.72 ? 33 LEU A CG 1 ATOM 126 C CD1 . LEU A 1 33 ? -83.192 26.991 283.104 1.00 22.52 ? 33 LEU A CD1 1 ATOM 127 C CD2 . LEU A 1 33 ? -81.703 28.654 284.228 1.00 30.69 ? 33 LEU A CD2 1 ATOM 128 N N . VAL A 1 34 ? -83.353 25.936 288.810 1.00 29.03 ? 34 VAL A N 1 ATOM 129 C CA . VAL A 1 34 ? -84.021 26.017 290.107 1.00 23.08 ? 34 VAL A CA 1 ATOM 130 C C . VAL A 1 34 ? -83.375 24.950 290.984 1.00 22.64 ? 34 VAL A C 1 ATOM 131 O O . VAL A 1 34 ? -83.713 23.766 290.881 1.00 23.85 ? 34 VAL A O 1 ATOM 132 C CB . VAL A 1 34 ? -85.538 25.806 290.007 1.00 22.01 ? 34 VAL A CB 1 ATOM 133 C CG1 . VAL A 1 34 ? -86.185 25.909 291.377 1.00 21.65 ? 34 VAL A CG1 1 ATOM 134 C CG2 . VAL A 1 34 ? -86.163 26.815 289.053 1.00 27.55 ? 34 VAL A CG2 1 ATOM 135 N N . GLU A 1 35 ? -82.453 25.360 291.851 1.00 22.32 ? 35 GLU A N 1 ATOM 136 C CA . GLU A 1 35 ? -81.818 24.410 292.754 1.00 22.68 ? 35 GLU A CA 1 ATOM 137 C C . GLU A 1 35 ? -82.824 23.867 293.760 1.00 22.23 ? 35 GLU A C 1 ATOM 138 O O . GLU A 1 35 ? -83.804 24.527 294.113 1.00 24.52 ? 35 GLU A O 1 ATOM 139 C CB . GLU A 1 35 ? -80.654 25.059 293.501 1.00 30.66 ? 35 GLU A CB 1 ATOM 140 C CG . GLU A 1 35 ? -79.479 25.486 292.640 1.00 39.34 ? 35 GLU A CG 1 ATOM 141 C CD . GLU A 1 35 ? -78.305 25.953 293.482 1.00 40.69 ? 35 GLU A CD 1 ATOM 142 O OE1 . GLU A 1 35 ? -78.244 25.576 294.670 1.00 47.54 ? 35 GLU A OE1 1 ATOM 143 O OE2 . GLU A 1 35 ? -77.436 26.681 292.960 1.00 44.14 ? 35 GLU A OE2 1 ATOM 144 N N . ILE A 1 36 ? -82.563 22.650 294.228 1.00 20.23 ? 36 ILE A N 1 ATOM 145 C CA . ILE A 1 36 ? -83.391 21.982 295.223 1.00 21.69 ? 36 ILE A CA 1 ATOM 146 C C . ILE A 1 36 ? -82.490 21.545 296.368 1.00 22.15 ? 36 ILE A C 1 ATOM 147 O O . ILE A 1 36 ? -81.596 20.713 296.176 1.00 25.06 ? 36 ILE A O 1 ATOM 148 C CB . ILE A 1 36 ? -84.139 20.774 294.637 1.00 23.54 ? 36 ILE A CB 1 ATOM 149 C CG1 . ILE A 1 36 ? -85.066 21.216 293.504 1.00 24.05 ? 36 ILE A CG1 1 ATOM 150 C CG2 . ILE A 1 36 ? -84.917 20.058 295.725 1.00 22.83 ? 36 ILE A CG2 1 ATOM 151 C CD1 . ILE A 1 36 ? -86.126 22.200 293.938 1.00 47.52 ? 36 ILE A CD1 1 ATOM 152 N N . ASN A 1 37 ? -82.716 22.111 297.549 1.00 22.65 ? 37 ASN A N 1 ATOM 153 C CA . ASN A 1 37 ? -82.010 21.691 298.753 1.00 22.82 ? 37 ASN A CA 1 ATOM 154 C C . ASN A 1 37 ? -82.750 20.484 299.316 1.00 25.52 ? 37 ASN A C 1 ATOM 155 O O . ASN A 1 37 ? -83.883 20.608 299.790 1.00 42.79 ? 37 ASN A O 1 ATOM 156 C CB . ASN A 1 37 ? -81.943 22.844 299.753 1.00 25.23 ? 37 ASN A CB 1 ATOM 157 C CG . ASN A 1 37 ? -81.292 22.460 301.081 1.00 34.20 ? 37 ASN A CG 1 ATOM 158 O OD1 . ASN A 1 37 ? -81.171 21.286 301.429 1.00 37.38 ? 37 ASN A OD1 1 ATOM 159 N ND2 . ASN A 1 37 ? -80.867 23.469 301.832 1.00 34.45 ? 37 ASN A ND2 1 ATOM 160 N N . TYR A 1 38 ? -82.113 19.316 299.264 1.00 24.94 ? 38 TYR A N 1 ATOM 161 C CA . TYR A 1 38 ? -82.745 18.071 299.679 1.00 27.42 ? 38 TYR A CA 1 ATOM 162 C C . TYR A 1 38 ? -82.664 17.827 301.181 1.00 28.38 ? 38 TYR A C 1 ATOM 163 O O . TYR A 1 38 ? -83.033 16.740 301.638 1.00 28.29 ? 38 TYR A O 1 ATOM 164 C CB . TYR A 1 38 ? -82.126 16.894 298.921 1.00 25.99 ? 38 TYR A CB 1 ATOM 165 C CG . TYR A 1 38 ? -82.580 16.810 297.484 1.00 22.32 ? 38 TYR A CG 1 ATOM 166 C CD1 . TYR A 1 38 ? -83.700 16.070 297.133 1.00 23.99 ? 38 TYR A CD1 1 ATOM 167 C CD2 . TYR A 1 38 ? -81.897 17.481 296.478 1.00 22.27 ? 38 TYR A CD2 1 ATOM 168 C CE1 . TYR A 1 38 ? -84.124 15.993 295.822 1.00 25.63 ? 38 TYR A CE1 1 ATOM 169 C CE2 . TYR A 1 38 ? -82.314 17.410 295.163 1.00 24.12 ? 38 TYR A CE2 1 ATOM 170 C CZ . TYR A 1 38 ? -83.428 16.665 294.841 1.00 27.18 ? 38 TYR A CZ 1 ATOM 171 O OH . TYR A 1 38 ? -83.851 16.588 293.535 1.00 25.64 ? 38 TYR A OH 1 ATOM 172 N N . GLU A 1 39 ? -82.194 18.805 301.955 1.00 31.25 ? 39 GLU A N 1 ATOM 173 C CA . GLU A 1 39 ? -82.195 18.711 303.407 1.00 29.77 ? 39 GLU A CA 1 ATOM 174 C C . GLU A 1 39 ? -83.129 19.711 304.070 1.00 29.35 ? 39 GLU A C 1 ATOM 175 O O . GLU A 1 39 ? -83.323 19.637 305.288 1.00 30.74 ? 39 GLU A O 1 ATOM 176 C CB . GLU A 1 39 ? -80.774 18.907 303.961 1.00 34.27 ? 39 GLU A CB 1 ATOM 177 C CG . GLU A 1 39 ? -79.776 17.834 303.545 1.00 42.67 ? 39 GLU A CG 1 ATOM 178 C CD . GLU A 1 39 ? -79.052 18.167 302.254 1.00 64.26 ? 39 GLU A CD 1 ATOM 179 O OE1 . GLU A 1 39 ? -79.368 19.207 301.641 1.00 45.50 ? 39 GLU A OE1 1 ATOM 180 O OE2 . GLU A 1 39 ? -78.159 17.390 301.855 1.00 47.34 ? 39 GLU A OE2 1 ATOM 181 N N . ALA A 1 40 ? -83.714 20.631 303.310 1.00 25.46 ? 40 ALA A N 1 ATOM 182 C CA . ALA A 1 40 ? -84.545 21.674 303.884 1.00 26.46 ? 40 ALA A CA 1 ATOM 183 C C . ALA A 1 40 ? -85.965 21.172 304.129 1.00 31.93 ? 40 ALA A C 1 ATOM 184 O O . ALA A 1 40 ? -86.437 20.218 303.504 1.00 41.07 ? 40 ALA A O 1 ATOM 185 C CB . ALA A 1 40 ? -84.578 22.899 302.969 1.00 29.46 ? 40 ALA A CB 1 ATOM 186 N N . THR A 1 41 ? -86.644 21.834 305.064 1.00 35.78 ? 41 THR A N 1 ATOM 187 C CA . THR A 1 41 ? -88.044 21.566 305.362 1.00 29.35 ? 41 THR A CA 1 ATOM 188 C C . THR A 1 41 ? -88.967 22.718 305.005 1.00 26.92 ? 41 THR A C 1 ATOM 189 O O . THR A 1 41 ? -90.124 22.479 304.656 1.00 27.92 ? 41 THR A O 1 ATOM 190 C CB . THR A 1 41 ? -88.222 21.236 306.850 1.00 40.35 ? 41 THR A CB 1 ATOM 191 O OG1 . THR A 1 41 ? -87.385 22.094 307.636 1.00 49.27 ? 41 THR A OG1 1 ATOM 192 C CG2 . THR A 1 41 ? -87.848 19.788 307.124 1.00 33.98 ? 41 THR A CG2 1 ATOM 193 N N . ALA A 1 42 ? -88.485 23.955 305.084 1.00 28.96 ? 42 ALA A N 1 ATOM 194 C CA . ALA A 1 42 ? -89.285 25.112 304.721 1.00 25.79 ? 42 ALA A CA 1 ATOM 195 C C . ALA A 1 42 ? -89.205 25.363 303.220 1.00 25.27 ? 42 ALA A C 1 ATOM 196 O O . ALA A 1 42 ? -88.249 24.970 302.548 1.00 26.15 ? 42 ALA A O 1 ATOM 197 C CB . ALA A 1 42 ? -88.823 26.351 305.487 1.00 27.33 ? 42 ALA A CB 1 ATOM 198 N N . TYR A 1 43 ? -90.230 26.040 302.696 1.00 22.49 ? 43 TYR A N 1 ATOM 199 C CA . TYR A 1 43 ? -90.321 26.233 301.253 1.00 27.76 ? 43 TYR A CA 1 ATOM 200 C C . TYR A 1 43 ? -89.336 27.288 300.763 1.00 31.39 ? 43 TYR A C 1 ATOM 201 O O . TYR A 1 43 ? -88.778 27.159 299.667 1.00 38.13 ? 43 TYR A O 1 ATOM 202 C CB . TYR A 1 43 ? -91.749 26.611 300.862 1.00 23.76 ? 43 TYR A CB 1 ATOM 203 C CG . TYR A 1 43 ? -91.951 26.763 299.371 1.00 21.10 ? 43 TYR A CG 1 ATOM 204 C CD1 . TYR A 1 43 ? -92.186 25.656 298.567 1.00 20.31 ? 43 TYR A CD1 1 ATOM 205 C CD2 . TYR A 1 43 ? -91.908 28.012 298.768 1.00 21.47 ? 43 TYR A CD2 1 ATOM 206 C CE1 . TYR A 1 43 ? -92.370 25.789 297.205 1.00 20.27 ? 43 TYR A CE1 1 ATOM 207 C CE2 . TYR A 1 43 ? -92.092 28.155 297.406 1.00 22.39 ? 43 TYR A CE2 1 ATOM 208 C CZ . TYR A 1 43 ? -92.323 27.040 296.630 1.00 19.68 ? 43 TYR A CZ 1 ATOM 209 O OH . TYR A 1 43 ? -92.507 27.176 295.274 1.00 19.39 ? 43 TYR A OH 1 ATOM 210 N N . GLU A 1 44 ? -89.112 28.341 301.553 1.00 35.55 ? 44 GLU A N 1 ATOM 211 C CA . GLU A 1 44 ? -88.205 29.400 301.120 1.00 29.06 ? 44 GLU A CA 1 ATOM 212 C C . GLU A 1 44 ? -86.764 28.915 301.043 1.00 33.60 ? 44 GLU A C 1 ATOM 213 O O . GLU A 1 44 ? -85.978 29.438 300.245 1.00 28.34 ? 44 GLU A O 1 ATOM 214 C CB . GLU A 1 44 ? -88.314 30.604 302.055 1.00 30.89 ? 44 GLU A CB 1 ATOM 215 C CG . GLU A 1 44 ? -89.646 31.325 301.967 1.00 31.29 ? 44 GLU A CG 1 ATOM 216 C CD . GLU A 1 44 ? -89.559 32.771 302.412 1.00 38.32 ? 44 GLU A CD 1 ATOM 217 O OE1 . GLU A 1 44 ? -88.733 33.072 303.298 1.00 60.75 ? 44 GLU A OE1 1 ATOM 218 O OE2 . GLU A 1 44 ? -90.316 33.607 301.874 1.00 38.42 ? 44 GLU A OE2 1 ATOM 219 N N . ASN A 1 45 ? -86.398 27.926 301.855 1.00 29.76 ? 45 ASN A N 1 ATOM 220 C CA . ASN A 1 45 ? -85.078 27.315 301.796 1.00 30.48 ? 45 ASN A CA 1 ATOM 221 C C . ASN A 1 45 ? -85.071 26.011 301.011 1.00 30.17 ? 45 ASN A C 1 ATOM 222 O O . ASN A 1 45 ? -84.012 25.391 300.874 1.00 29.06 ? 45 ASN A O 1 ATOM 223 C CB . ASN A 1 45 ? -84.542 27.077 303.211 1.00 28.95 ? 45 ASN A CB 1 ATOM 224 C CG . ASN A 1 45 ? -84.548 28.337 304.053 1.00 39.78 ? 45 ASN A CG 1 ATOM 225 O OD1 . ASN A 1 45 ? -84.386 29.443 303.536 1.00 37.94 ? 45 ASN A OD1 1 ATOM 226 N ND2 . ASN A 1 45 ? -84.732 28.178 305.359 1.00 52.62 ? 45 ASN A ND2 1 ATOM 227 N N . LEU A 1 46 ? -86.224 25.584 300.495 1.00 28.84 ? 46 LEU A N 1 ATOM 228 C CA . LEU A 1 46 ? -86.280 24.379 299.675 1.00 28.48 ? 46 LEU A CA 1 ATOM 229 C C . LEU A 1 46 ? -85.781 24.646 298.261 1.00 24.16 ? 46 LEU A C 1 ATOM 230 O O . LEU A 1 46 ? -84.995 23.865 297.712 1.00 22.67 ? 46 LEU A O 1 ATOM 231 C CB . LEU A 1 46 ? -87.709 23.837 299.631 1.00 23.86 ? 46 LEU A CB 1 ATOM 232 C CG . LEU A 1 46 ? -87.966 22.742 298.593 1.00 23.77 ? 46 LEU A CG 1 ATOM 233 C CD1 . LEU A 1 46 ? -87.241 21.461 298.965 1.00 25.02 ? 46 LEU A CD1 1 ATOM 234 C CD2 . LEU A 1 46 ? -89.457 22.501 298.413 1.00 28.88 ? 46 LEU A CD2 1 ATOM 235 N N . ILE A 1 47 ? -86.234 25.738 297.654 1.00 23.84 ? 47 ILE A N 1 ATOM 236 C CA . ILE A 1 47 ? -85.950 26.028 296.259 1.00 27.83 ? 47 ILE A CA 1 ATOM 237 C C . ILE A 1 47 ? -85.055 27.256 296.167 1.00 29.04 ? 47 ILE A C 1 ATOM 238 O O . ILE A 1 47 ? -84.974 28.078 297.085 1.00 36.07 ? 47 ILE A O 1 ATOM 239 C CB . ILE A 1 47 ? -87.243 26.236 295.446 1.00 25.62 ? 47 ILE A CB 1 ATOM 240 C CG1 . ILE A 1 47 ? -88.006 27.455 295.967 1.00 21.17 ? 47 ILE A CG1 1 ATOM 241 C CG2 . ILE A 1 47 ? -88.114 24.993 295.511 1.00 23.71 ? 47 ILE A CG2 1 ATOM 242 C CD1 . ILE A 1 47 ? -89.214 27.818 295.136 1.00 29.98 ? 47 ILE A CD1 1 ATOM 243 N N . LYS A 1 48 ? -84.372 27.370 295.032 1.00 24.60 ? 48 LYS A N 1 ATOM 244 C CA . LYS A 1 48 ? -83.524 28.522 294.727 1.00 24.92 ? 48 LYS A CA 1 ATOM 245 C C . LYS A 1 48 ? -83.677 28.842 293.249 1.00 28.01 ? 48 LYS A C 1 ATOM 246 O O . LYS A 1 48 ? -82.861 28.429 292.416 1.00 27.29 ? 48 LYS A O 1 ATOM 247 C CB . LYS A 1 48 ? -82.063 28.246 295.089 1.00 36.77 ? 48 LYS A CB 1 ATOM 248 C CG . LYS A 1 48 ? -81.156 29.462 294.984 1.00 69.37 ? 48 LYS A CG 1 ATOM 249 C CD . LYS A 1 48 ? -79.705 29.099 295.257 1.00 46.67 ? 48 LYS A CD 1 ATOM 250 C CE . LYS A 1 48 ? -78.862 30.340 295.505 1.00 50.34 ? 48 LYS A CE 1 ATOM 251 N NZ . LYS A 1 48 ? -77.459 29.997 295.869 1.00 62.11 ? 48 LYS A NZ 1 ATOM 252 N N . PRO A 1 49 ? -84.733 29.569 292.881 1.00 32.19 ? 49 PRO A N 1 ATOM 253 C CA . PRO A 1 49 ? -84.919 29.930 291.470 1.00 29.20 ? 49 PRO A CA 1 ATOM 254 C C . PRO A 1 49 ? -83.819 30.867 291.001 1.00 32.96 ? 49 PRO A C 1 ATOM 255 O O . PRO A 1 49 ? -83.370 31.746 291.740 1.00 31.61 ? 49 PRO A O 1 ATOM 256 C CB . PRO A 1 49 ? -86.290 30.619 291.452 1.00 29.68 ? 49 PRO A CB 1 ATOM 257 C CG . PRO A 1 49 ? -86.946 30.231 292.746 1.00 27.15 ? 49 PRO A CG 1 ATOM 258 C CD . PRO A 1 49 ? -85.833 30.057 293.726 1.00 34.65 ? 49 PRO A CD 1 ATOM 259 N N . LYS A 1 50 ? -83.384 30.672 289.759 1.00 34.25 ? 50 LYS A N 1 ATOM 260 C CA . LYS A 1 50 ? -82.265 31.420 289.203 1.00 38.43 ? 50 LYS A CA 1 ATOM 261 C C . LYS A 1 50 ? -82.705 32.227 287.994 1.00 42.06 ? 50 LYS A C 1 ATOM 262 O O . LYS A 1 50 ? -83.432 31.725 287.131 1.00 38.27 ? 50 LYS A O 1 ATOM 263 C CB . LYS A 1 50 ? -81.113 30.494 288.811 1.00 36.24 ? 50 LYS A CB 1 ATOM 264 C CG . LYS A 1 50 ? -80.367 29.912 289.989 1.00 34.54 ? 50 LYS A CG 1 ATOM 265 C CD . LYS A 1 50 ? -79.109 29.206 289.531 1.00 33.48 ? 50 LYS A CD 1 ATOM 266 C CE . LYS A 1 50 ? -78.487 28.429 290.667 1.00 37.34 ? 50 LYS A CE 1 ATOM 267 N NZ . LYS A 1 50 ? -77.904 29.330 291.699 1.00 43.15 ? 50 LYS A NZ 1 ATOM 268 N N . GLU A 1 51 ? -82.256 33.482 287.949 1.00 49.09 ? 51 GLU A N 1 ATOM 269 C CA . GLU A 1 51 ? -82.398 34.302 286.753 1.00 50.33 ? 51 GLU A CA 1 ATOM 270 C C . GLU A 1 51 ? -81.762 33.619 285.548 1.00 52.70 ? 51 GLU A C 1 ATOM 271 O O . GLU A 1 51 ? -82.348 33.567 284.461 1.00 42.91 ? 51 GLU A O 1 ATOM 272 C CB . GLU A 1 51 ? -81.768 35.680 286.997 1.00 66.17 ? 51 GLU A CB 1 ATOM 273 C CG . GLU A 1 51 ? -80.303 35.665 287.487 1.00 82.19 ? 51 GLU A CG 1 ATOM 274 C CD . GLU A 1 51 ? -80.129 35.168 288.920 1.00 74.37 ? 51 GLU A CD 1 ATOM 275 O OE1 . GLU A 1 51 ? -81.145 34.881 289.588 1.00 87.79 ? 51 GLU A OE1 1 ATOM 276 O OE2 . GLU A 1 51 ? -78.970 35.042 289.370 1.00 55.07 ? 51 GLU A OE2 1 ATOM 277 N N . GLN A 1 52 ? -80.562 33.075 285.733 1.00 58.81 ? 52 GLN A N 1 ATOM 278 C CA . GLN A 1 52 ? -79.821 32.406 284.675 1.00 36.68 ? 52 GLN A CA 1 ATOM 279 C C . GLN A 1 52 ? -78.908 31.375 285.322 1.00 35.32 ? 52 GLN A C 1 ATOM 280 O O . GLN A 1 52 ? -78.821 31.277 286.549 1.00 39.71 ? 52 GLN A O 1 ATOM 281 C CB . GLN A 1 52 ? -79.015 33.408 283.842 1.00 37.39 ? 52 GLN A CB 1 ATOM 282 C CG . GLN A 1 52 ? -77.911 34.097 284.631 1.00 40.33 ? 52 GLN A CG 1 ATOM 283 C CD . GLN A 1 52 ? -77.413 35.367 283.971 1.00 36.25 ? 52 GLN A CD 1 ATOM 284 O OE1 . GLN A 1 52 ? -78.196 36.149 283.433 1.00 36.27 ? 52 GLN A OE1 1 ATOM 285 N NE2 . GLN A 1 52 ? -76.103 35.579 284.011 1.00 48.85 ? 52 GLN A NE2 1 ATOM 286 N N . VAL A 1 53 ? -78.219 30.604 284.487 1.00 29.79 ? 53 VAL A N 1 ATOM 287 C CA . VAL A 1 53 ? -77.207 29.665 284.949 1.00 30.97 ? 53 VAL A CA 1 ATOM 288 C C . VAL A 1 53 ? -75.928 29.925 284.168 1.00 25.73 ? 53 VAL A C 1 ATOM 289 O O . VAL A 1 53 ? -75.971 30.281 282.984 1.00 35.63 ? 53 VAL A O 1 ATOM 290 C CB . VAL A 1 53 ? -77.667 28.196 284.808 1.00 30.72 ? 53 VAL A CB 1 ATOM 291 C CG1 . VAL A 1 53 ? -77.743 27.778 283.348 1.00 24.24 ? 53 VAL A CG1 1 ATOM 292 C CG2 . VAL A 1 53 ? -76.752 27.276 285.597 1.00 28.88 ? 53 VAL A CG2 1 ATOM 293 N N . ASP A 1 54 ? -74.790 29.774 284.837 1.00 24.76 ? 54 ASP A N 1 ATOM 294 C CA . ASP A 1 54 ? -73.485 30.092 284.265 1.00 29.28 ? 54 ASP A CA 1 ATOM 295 C C . ASP A 1 54 ? -72.701 28.795 284.099 1.00 25.12 ? 54 ASP A C 1 ATOM 296 O O . ASP A 1 54 ? -72.193 28.236 285.075 1.00 22.23 ? 54 ASP A O 1 ATOM 297 C CB . ASP A 1 54 ? -72.739 31.090 285.145 1.00 28.85 ? 54 ASP A CB 1 ATOM 298 C CG . ASP A 1 54 ? -73.401 32.452 285.168 1.00 34.18 ? 54 ASP A CG 1 ATOM 299 O OD1 . ASP A 1 54 ? -73.325 33.170 284.149 1.00 27.79 ? 54 ASP A OD1 1 ATOM 300 O OD2 . ASP A 1 54 ? -74.002 32.802 286.205 1.00 41.27 ? 54 ASP A OD2 1 ATOM 301 N N . VAL A 1 55 ? -72.606 28.322 282.860 1.00 22.27 ? 55 VAL A N 1 ATOM 302 C CA . VAL A 1 55 ? -71.825 27.131 282.545 1.00 22.29 ? 55 VAL A CA 1 ATOM 303 C C . VAL A 1 55 ? -70.354 27.530 282.510 1.00 25.32 ? 55 VAL A C 1 ATOM 304 O O . VAL A 1 55 ? -69.932 28.304 281.648 1.00 46.98 ? 55 VAL A O 1 ATOM 305 C CB . VAL A 1 55 ? -72.263 26.506 281.216 1.00 23.81 ? 55 VAL A CB 1 ATOM 306 C CG1 . VAL A 1 55 ? -71.329 25.369 280.832 1.00 28.98 ? 55 VAL A CG1 1 ATOM 307 C CG2 . VAL A 1 55 ? -73.696 26.012 281.312 1.00 24.40 ? 55 VAL A CG2 1 ATOM 308 N N . GLN A 1 56 ? -69.573 27.005 283.449 1.00 31.27 ? 56 GLN A N 1 ATOM 309 C CA . GLN A 1 56 ? -68.157 27.321 283.559 1.00 25.99 ? 56 GLN A CA 1 ATOM 310 C C . GLN A 1 56 ? -67.322 26.207 282.943 1.00 26.32 ? 56 GLN A C 1 ATOM 311 O O . GLN A 1 56 ? -67.583 25.022 283.171 1.00 30.64 ? 56 GLN A O 1 ATOM 312 C CB . GLN A 1 56 ? -67.757 27.526 285.021 1.00 26.15 ? 56 GLN A CB 1 ATOM 313 C CG . GLN A 1 56 ? -68.298 28.805 285.636 1.00 28.86 ? 56 GLN A CG 1 ATOM 314 C CD . GLN A 1 56 ? -67.982 28.919 287.114 1.00 38.26 ? 56 GLN A CD 1 ATOM 315 O OE1 . GLN A 1 56 ? -67.738 27.918 287.786 1.00 61.94 ? 56 GLN A OE1 1 ATOM 316 N NE2 . GLN A 1 56 ? -67.988 30.143 287.628 1.00 42.56 ? 56 GLN A NE2 1 ATOM 317 N N . VAL A 1 57 ? -66.316 26.596 282.162 1.00 26.51 ? 57 VAL A N 1 ATOM 318 C CA . VAL A 1 57 ? -65.426 25.651 281.497 1.00 30.74 ? 57 VAL A CA 1 ATOM 319 C C . VAL A 1 57 ? -64.000 26.177 281.584 1.00 30.26 ? 57 VAL A C 1 ATOM 320 O O . VAL A 1 57 ? -63.750 27.360 281.326 1.00 39.67 ? 57 VAL A O 1 ATOM 321 C CB . VAL A 1 57 ? -65.835 25.415 280.029 1.00 30.15 ? 57 VAL A CB 1 ATOM 322 C CG1 . VAL A 1 57 ? -66.113 26.733 279.329 1.00 27.70 ? 57 VAL A CG1 1 ATOM 323 C CG2 . VAL A 1 57 ? -64.760 24.632 279.290 1.00 28.95 ? 57 VAL A CG2 1 ATOM 324 N N . SER A 1 58 ? -63.070 25.302 281.961 1.00 27.36 ? 58 SER A N 1 ATOM 325 C CA . SER A 1 58 ? -61.654 25.626 282.016 1.00 29.88 ? 58 SER A CA 1 ATOM 326 C C . SER A 1 58 ? -60.865 24.497 281.372 1.00 30.36 ? 58 SER A C 1 ATOM 327 O O . SER A 1 58 ? -61.299 23.342 281.369 1.00 31.00 ? 58 SER A O 1 ATOM 328 C CB . SER A 1 58 ? -61.182 25.847 283.457 1.00 31.57 ? 58 SER A CB 1 ATOM 329 O OG . SER A 1 58 ? -62.114 26.636 284.177 1.00 33.86 ? 58 SER A OG 1 ATOM 330 N N . TRP A 1 59 ? -59.699 24.835 280.826 1.00 28.71 ? 59 TRP A N 1 ATOM 331 C CA . TRP A 1 59 ? -58.925 23.856 280.080 1.00 28.67 ? 59 TRP A CA 1 ATOM 332 C C . TRP A 1 59 ? -57.439 24.155 280.203 1.00 30.56 ? 59 TRP A C 1 ATOM 333 O O . TRP A 1 59 ? -57.030 25.257 280.577 1.00 31.11 ? 59 TRP A O 1 ATOM 334 C CB . TRP A 1 59 ? -59.336 23.828 278.603 1.00 39.94 ? 59 TRP A CB 1 ATOM 335 C CG . TRP A 1 59 ? -58.996 25.080 277.853 1.00 33.31 ? 59 TRP A CG 1 ATOM 336 C CD1 . TRP A 1 59 ? -57.891 25.300 277.083 1.00 30.78 ? 59 TRP A CD1 1 ATOM 337 C CD2 . TRP A 1 59 ? -59.768 26.286 277.800 1.00 33.45 ? 59 TRP A CD2 1 ATOM 338 N NE1 . TRP A 1 59 ? -57.927 26.567 276.554 1.00 32.54 ? 59 TRP A NE1 1 ATOM 339 C CE2 . TRP A 1 59 ? -59.069 27.193 276.979 1.00 35.48 ? 59 TRP A CE2 1 ATOM 340 C CE3 . TRP A 1 59 ? -60.982 26.686 278.366 1.00 39.19 ? 59 TRP A CE3 1 ATOM 341 C CZ2 . TRP A 1 59 ? -59.544 28.475 276.710 1.00 40.08 ? 59 TRP A CZ2 1 ATOM 342 C CZ3 . TRP A 1 59 ? -61.451 27.960 278.099 1.00 31.57 ? 59 TRP A CZ3 1 ATOM 343 C CH2 . TRP A 1 59 ? -60.733 28.839 277.279 1.00 31.91 ? 59 TRP A CH2 1 ATOM 344 N N . ASN A 1 60 ? -56.636 23.143 279.885 1.00 31.15 ? 60 ASN A N 1 ATOM 345 C CA . ASN A 1 60 ? -55.192 23.265 279.775 1.00 27.55 ? 60 ASN A CA 1 ATOM 346 C C . ASN A 1 60 ? -54.773 22.884 278.362 1.00 28.95 ? 60 ASN A C 1 ATOM 347 O O . ASN A 1 60 ? -55.499 22.193 277.642 1.00 35.71 ? 60 ASN A O 1 ATOM 348 C CB . ASN A 1 60 ? -54.474 22.382 280.802 1.00 26.76 ? 60 ASN A CB 1 ATOM 349 C CG . ASN A 1 60 ? -54.781 22.784 282.229 1.00 30.73 ? 60 ASN A CG 1 ATOM 350 O OD1 . ASN A 1 60 ? -54.903 23.969 282.539 1.00 31.76 ? 60 ASN A OD1 1 ATOM 351 N ND2 . ASN A 1 60 ? -54.907 21.798 283.109 1.00 47.41 ? 60 ASN A ND2 1 ATOM 352 N N . VAL A 1 61 ? -53.588 23.340 277.965 1.00 26.57 ? 61 VAL A N 1 ATOM 353 C CA . VAL A 1 61 ? -53.109 23.197 276.596 1.00 28.45 ? 61 VAL A CA 1 ATOM 354 C C . VAL A 1 61 ? -51.898 22.275 276.582 1.00 34.97 ? 61 VAL A C 1 ATOM 355 O O . VAL A 1 61 ? -50.942 22.478 277.340 1.00 37.22 ? 61 VAL A O 1 ATOM 356 C CB . VAL A 1 61 ? -52.767 24.562 275.977 1.00 36.38 ? 61 VAL A CB 1 ATOM 357 C CG1 . VAL A 1 61 ? -52.381 24.398 274.521 1.00 44.43 ? 61 VAL A CG1 1 ATOM 358 C CG2 . VAL A 1 61 ? -53.947 25.510 276.111 1.00 67.96 ? 61 VAL A CG2 1 ATOM 359 N N . TRP A 1 62 ? -51.946 21.263 275.721 1.00 38.66 ? 62 TRP A N 1 ATOM 360 C CA . TRP A 1 62 ? -50.819 20.388 275.445 1.00 51.99 ? 62 TRP A CA 1 ATOM 361 C C . TRP A 1 62 ? -50.567 20.386 273.943 1.00 50.34 ? 62 TRP A C 1 ATOM 362 O O . TRP A 1 62 ? -51.448 20.724 273.150 1.00 43.75 ? 62 TRP A O 1 ATOM 363 C CB . TRP A 1 62 ? -51.075 18.955 275.941 1.00 44.50 ? 62 TRP A CB 1 ATOM 364 C CG . TRP A 1 62 ? -51.535 18.871 277.372 1.00 40.88 ? 62 TRP A CG 1 ATOM 365 C CD1 . TRP A 1 62 ? -52.794 19.106 277.846 1.00 38.21 ? 62 TRP A CD1 1 ATOM 366 C CD2 . TRP A 1 62 ? -50.743 18.506 278.509 1.00 46.07 ? 62 TRP A CD2 1 ATOM 367 N NE1 . TRP A 1 62 ? -52.831 18.923 279.207 1.00 37.90 ? 62 TRP A NE1 1 ATOM 368 C CE2 . TRP A 1 62 ? -51.584 18.553 279.638 1.00 42.30 ? 62 TRP A CE2 1 ATOM 369 C CE3 . TRP A 1 62 ? -49.402 18.150 278.681 1.00 64.52 ? 62 TRP A CE3 1 ATOM 370 C CZ2 . TRP A 1 62 ? -51.129 18.256 280.921 1.00 49.51 ? 62 TRP A CZ2 1 ATOM 371 C CZ3 . TRP A 1 62 ? -48.953 17.857 279.954 1.00 79.05 ? 62 TRP A CZ3 1 ATOM 372 C CH2 . TRP A 1 62 ? -49.813 17.911 281.058 1.00 58.60 ? 62 TRP A CH2 1 ATOM 373 N N . ASN A 1 63 ? -49.347 20.003 273.560 1.00 47.07 ? 63 ASN A N 1 ATOM 374 C CA . ASN A 1 63 ? -48.971 19.809 272.158 1.00 51.90 ? 63 ASN A CA 1 ATOM 375 C C . ASN A 1 63 ? -49.055 21.131 271.389 1.00 62.47 ? 63 ASN A C 1 ATOM 376 O O . ASN A 1 63 ? -49.777 21.276 270.398 1.00 92.84 ? 63 ASN A O 1 ATOM 377 C CB . ASN A 1 63 ? -49.827 18.712 271.513 1.00 56.75 ? 63 ASN A CB 1 ATOM 378 C CG . ASN A 1 63 ? -49.520 18.508 270.038 1.00 65.35 ? 63 ASN A CG 1 ATOM 379 O OD1 . ASN A 1 63 ? -48.478 18.929 269.534 1.00 72.24 ? 63 ASN A OD1 1 ATOM 380 N ND2 . ASN A 1 63 ? -50.453 17.885 269.332 1.00 58.62 ? 63 ASN A ND2 1 ATOM 381 N N . GLY A 1 64 ? -48.310 22.112 271.884 1.00 49.08 ? 64 GLY A N 1 ATOM 382 C CA . GLY A 1 64 ? -48.148 23.385 271.213 1.00 44.59 ? 64 GLY A CA 1 ATOM 383 C C . GLY A 1 64 ? -48.559 24.555 272.089 1.00 42.06 ? 64 GLY A C 1 ATOM 384 O O . GLY A 1 64 ? -48.672 24.456 273.316 1.00 41.46 ? 64 GLY A O 1 ATOM 385 N N . ASP A 1 65 ? -48.769 25.691 271.429 1.00 41.86 ? 65 ASP A N 1 ATOM 386 C CA . ASP A 1 65 ? -49.098 26.924 272.119 1.00 45.55 ? 65 ASP A CA 1 ATOM 387 C C . ASP A 1 65 ? -50.600 27.010 272.389 1.00 40.73 ? 65 ASP A C 1 ATOM 388 O O . ASP A 1 65 ? -51.390 26.153 271.984 1.00 48.96 ? 65 ASP A O 1 ATOM 389 C CB . ASP A 1 65 ? -48.623 28.125 271.308 1.00 46.71 ? 65 ASP A CB 1 ATOM 390 C CG . ASP A 1 65 ? -49.266 28.199 269.937 1.00 57.43 ? 65 ASP A CG 1 ATOM 391 O OD1 . ASP A 1 65 ? -48.750 27.561 269.002 1.00 85.33 ? 65 ASP A OD1 1 ATOM 392 O OD2 . ASP A 1 65 ? -50.286 28.909 269.795 1.00 51.54 ? 65 ASP A OD2 1 ATOM 393 N N . ILE A 1 66 ? -51.002 28.080 273.082 1.00 38.67 ? 66 ILE A N 1 ATOM 394 C CA . ILE A 1 66 ? -52.390 28.233 273.516 1.00 35.66 ? 66 ILE A CA 1 ATOM 395 C C . ILE A 1 66 ? -53.292 28.843 272.457 1.00 38.02 ? 66 ILE A C 1 ATOM 396 O O . ILE A 1 66 ? -54.508 28.924 272.669 1.00 38.24 ? 66 ILE A O 1 ATOM 397 C CB . ILE A 1 66 ? -52.462 29.093 274.791 1.00 33.39 ? 66 ILE A CB 1 ATOM 398 C CG1 . ILE A 1 66 ? -51.829 30.461 274.540 1.00 33.53 ? 66 ILE A CG1 1 ATOM 399 C CG2 . ILE A 1 66 ? -51.762 28.393 275.944 1.00 31.24 ? 66 ILE A CG2 1 ATOM 400 C CD1 . ILE A 1 66 ? -51.951 31.401 275.707 1.00 36.45 ? 66 ILE A CD1 1 ATOM 401 N N . GLY A 1 67 ? -52.744 29.274 271.329 1.00 37.20 ? 67 GLY A N 1 ATOM 402 C CA . GLY A 1 67 ? -53.541 29.860 270.274 1.00 35.46 ? 67 GLY A CA 1 ATOM 403 C C . GLY A 1 67 ? -53.833 31.332 270.510 1.00 34.02 ? 67 GLY A C 1 ATOM 404 O O . GLY A 1 67 ? -53.677 31.868 271.606 1.00 35.44 ? 67 GLY A O 1 ATOM 405 N N . ASP A 1 68 ? -54.275 31.996 269.440 1.00 32.52 ? 68 ASP A N 1 ATOM 406 C CA . ASP A 1 68 ? -54.527 33.432 269.510 1.00 35.46 ? 68 ASP A CA 1 ATOM 407 C C . ASP A 1 68 ? -55.913 33.742 270.064 1.00 42.98 ? 68 ASP A C 1 ATOM 408 O O . ASP A 1 68 ? -56.070 34.678 270.855 1.00 71.41 ? 68 ASP A O 1 ATOM 409 C CB . ASP A 1 68 ? -54.352 34.062 268.128 1.00 38.37 ? 68 ASP A CB 1 ATOM 410 C CG . ASP A 1 68 ? -52.934 33.938 267.607 1.00 38.87 ? 68 ASP A CG 1 ATOM 411 O OD1 . ASP A 1 68 ? -52.012 33.765 268.431 1.00 41.79 ? 68 ASP A OD1 1 ATOM 412 O OD2 . ASP A 1 68 ? -52.740 34.014 266.376 1.00 40.16 ? 68 ASP A OD2 1 ATOM 413 N N . ILE A 1 69 ? -56.927 32.976 269.663 1.00 33.73 ? 69 ILE A N 1 ATOM 414 C CA . ILE A 1 69 ? -58.300 33.212 270.093 1.00 31.61 ? 69 ILE A CA 1 ATOM 415 C C . ILE A 1 69 ? -58.924 31.882 270.493 1.00 30.67 ? 69 ILE A C 1 ATOM 416 O O . ILE A 1 69 ? -58.550 30.819 269.987 1.00 31.49 ? 69 ILE A O 1 ATOM 417 C CB . ILE A 1 69 ? -59.127 33.917 268.991 1.00 31.16 ? 69 ILE A CB 1 ATOM 418 C CG1 . ILE A 1 69 ? -60.425 34.489 269.565 1.00 31.50 ? 69 ILE A CG1 1 ATOM 419 C CG2 . ILE A 1 69 ? -59.409 32.970 267.834 1.00 34.85 ? 69 ILE A CG2 1 ATOM 420 C CD1 . ILE A 1 69 ? -61.084 35.518 268.672 1.00 39.53 ? 69 ILE A CD1 1 ATOM 421 N N . ALA A 1 70 ? -59.877 31.944 271.421 1.00 30.40 ? 70 ALA A N 1 ATOM 422 C CA . ALA A 1 70 ? -60.509 30.762 271.989 1.00 29.85 ? 70 ALA A CA 1 ATOM 423 C C . ALA A 1 70 ? -62.018 30.834 271.811 1.00 30.25 ? 70 ALA A C 1 ATOM 424 O O . ALA A 1 70 ? -62.629 31.882 272.038 1.00 32.29 ? 70 ALA A O 1 ATOM 425 C CB . ALA A 1 70 ? -60.169 30.623 273.476 1.00 29.17 ? 70 ALA A CB 1 ATOM 426 N N . TYR A 1 71 ? -62.616 29.713 271.413 1.00 28.93 ? 71 TYR A N 1 ATOM 427 C CA . TYR A 1 71 ? -64.057 29.598 271.254 1.00 27.68 ? 71 TYR A CA 1 ATOM 428 C C . TYR A 1 71 ? -64.595 28.469 272.122 1.00 26.24 ? 71 TYR A C 1 ATOM 429 O O . TYR A 1 71 ? -63.875 27.534 272.483 1.00 27.12 ? 71 TYR A O 1 ATOM 430 C CB . TYR A 1 71 ? -64.449 29.338 269.792 1.00 28.23 ? 71 TYR A CB 1 ATOM 431 C CG . TYR A 1 71 ? -63.926 30.350 268.800 1.00 28.23 ? 71 TYR A CG 1 ATOM 432 C CD1 . TYR A 1 71 ? -64.560 31.573 268.627 1.00 29.69 ? 71 TYR A CD1 1 ATOM 433 C CD2 . TYR A 1 71 ? -62.813 30.074 268.019 1.00 29.60 ? 71 TYR A CD2 1 ATOM 434 C CE1 . TYR A 1 71 ? -64.091 32.498 267.715 1.00 32.82 ? 71 TYR A CE1 1 ATOM 435 C CE2 . TYR A 1 71 ? -62.337 30.991 267.103 1.00 33.11 ? 71 TYR A CE2 1 ATOM 436 C CZ . TYR A 1 71 ? -62.980 32.202 266.955 1.00 34.41 ? 71 TYR A CZ 1 ATOM 437 O OH . TYR A 1 71 ? -62.510 33.119 266.045 1.00 44.52 ? 71 TYR A OH 1 ATOM 438 N N . VAL A 1 72 ? -65.880 28.570 272.453 1.00 26.21 ? 72 VAL A N 1 ATOM 439 C CA . VAL A 1 72 ? -66.626 27.511 273.121 1.00 26.32 ? 72 VAL A CA 1 ATOM 440 C C . VAL A 1 72 ? -67.809 27.151 272.236 1.00 26.66 ? 72 VAL A C 1 ATOM 441 O O . VAL A 1 72 ? -68.486 28.038 271.704 1.00 26.35 ? 72 VAL A O 1 ATOM 442 C CB . VAL A 1 72 ? -67.094 27.935 274.529 1.00 23.77 ? 72 VAL A CB 1 ATOM 443 C CG1 . VAL A 1 72 ? -67.954 26.851 275.156 1.00 23.47 ? 72 VAL A CG1 1 ATOM 444 C CG2 . VAL A 1 72 ? -65.897 28.243 275.412 1.00 21.57 ? 72 VAL A CG2 1 ATOM 445 N N . LEU A 1 73 ? -68.053 25.853 272.068 1.00 26.50 ? 73 LEU A N 1 ATOM 446 C CA . LEU A 1 73 ? -69.023 25.356 271.100 1.00 29.88 ? 73 LEU A CA 1 ATOM 447 C C . LEU A 1 73 ? -70.085 24.527 271.809 1.00 33.39 ? 73 LEU A C 1 ATOM 448 O O . LEU A 1 73 ? -69.761 23.547 272.488 1.00 37.07 ? 73 LEU A O 1 ATOM 449 C CB . LEU A 1 73 ? -68.328 24.529 270.017 1.00 27.63 ? 73 LEU A CB 1 ATOM 450 C CG . LEU A 1 73 ? -67.255 25.270 269.214 1.00 27.68 ? 73 LEU A CG 1 ATOM 451 C CD1 . LEU A 1 73 ? -66.711 24.393 268.098 1.00 33.25 ? 73 LEU A CD1 1 ATOM 452 C CD2 . LEU A 1 73 ? -67.798 26.577 268.660 1.00 30.45 ? 73 LEU A CD2 1 ATOM 453 N N . PHE A 1 74 ? -71.350 24.919 271.643 1.00 32.59 ? 74 PHE A N 1 ATOM 454 C CA . PHE A 1 74 ? -72.480 24.166 272.178 1.00 33.75 ? 74 PHE A CA 1 ATOM 455 C C . PHE A 1 74 ? -73.330 23.566 271.065 1.00 46.99 ? 74 PHE A C 1 ATOM 456 O O . PHE A 1 74 ? -74.521 23.882 270.990 1.00 102.62 ? 74 PHE A O 1 ATOM 457 C CB . PHE A 1 74 ? -73.387 25.051 273.040 1.00 32.78 ? 74 PHE A CB 1 ATOM 458 C CG . PHE A 1 74 ? -72.813 25.425 274.376 1.00 29.87 ? 74 PHE A CG 1 ATOM 459 C CD1 . PHE A 1 74 ? -71.579 24.960 274.789 1.00 28.35 ? 74 PHE A CD1 1 ATOM 460 C CD2 . PHE A 1 74 ? -73.536 26.241 275.231 1.00 28.60 ? 74 PHE A CD2 1 ATOM 461 C CE1 . PHE A 1 74 ? -71.075 25.316 276.025 1.00 41.95 ? 74 PHE A CE1 1 ATOM 462 C CE2 . PHE A 1 74 ? -73.037 26.595 276.465 1.00 30.64 ? 74 PHE A CE2 1 ATOM 463 C CZ . PHE A 1 74 ? -71.805 26.133 276.864 1.00 45.97 ? 74 PHE A CZ 1 ATOM 464 N N . ASP A 1 75 ? -72.718 22.720 270.218 1.00 44.94 ? 75 ASP A N 1 ATOM 465 C CA . ASP A 1 75 ? -73.279 21.977 269.079 1.00 54.34 ? 75 ASP A CA 1 ATOM 466 C C . ASP A 1 75 ? -72.434 22.217 267.835 1.00 50.64 ? 75 ASP A C 1 ATOM 467 O O . ASP A 1 75 ? -72.956 22.181 266.716 1.00 53.84 ? 75 ASP A O 1 ATOM 468 C CB . ASP A 1 75 ? -74.730 22.344 268.737 1.00 79.14 ? 75 ASP A CB 1 ATOM 469 C CG . ASP A 1 75 ? -75.740 21.672 269.647 1.00 77.56 ? 75 ASP A CG 1 ATOM 470 O OD1 . ASP A 1 75 ? -75.457 20.561 270.142 1.00 54.12 ? 75 ASP A OD1 1 ATOM 471 O OD2 . ASP A 1 75 ? -76.818 22.264 269.869 1.00 58.70 ? 75 ASP A OD2 1 ATOM 472 N N . GLU A 1 76 ? -71.136 22.458 268.021 1.00 45.05 ? 76 GLU A N 1 ATOM 473 C CA . GLU A 1 76 ? -70.236 22.931 266.968 1.00 48.29 ? 76 GLU A CA 1 ATOM 474 C C . GLU A 1 76 ? -70.647 24.301 266.438 1.00 59.14 ? 76 GLU A C 1 ATOM 475 O O . GLU A 1 76 ? -70.280 24.674 265.319 1.00 83.42 ? 76 GLU A O 1 ATOM 476 C CB . GLU A 1 76 ? -70.129 21.929 265.810 1.00 53.32 ? 76 GLU A CB 1 ATOM 477 C CG . GLU A 1 76 ? -69.677 20.538 266.215 1.00 52.06 ? 76 GLU A CG 1 ATOM 478 C CD . GLU A 1 76 ? -69.812 19.535 265.085 1.00 44.76 ? 76 GLU A CD 1 ATOM 479 O OE1 . GLU A 1 76 ? -69.178 19.739 264.028 1.00 51.57 ? 76 GLU A OE1 1 ATOM 480 O OE2 . GLU A 1 76 ? -70.554 18.545 265.252 1.00 43.48 ? 76 GLU A OE2 1 ATOM 481 N N . GLN A 1 77 ? -71.410 25.057 267.224 1.00 47.22 ? 77 GLN A N 1 ATOM 482 C CA . GLN A 1 77 ? -71.788 26.424 266.898 1.00 50.43 ? 77 GLN A CA 1 ATOM 483 C C . GLN A 1 77 ? -71.351 27.344 268.029 1.00 36.94 ? 77 GLN A C 1 ATOM 484 O O . GLN A 1 77 ? -71.445 26.984 269.207 1.00 34.73 ? 77 GLN A O 1 ATOM 485 C CB . GLN A 1 77 ? -73.299 26.545 266.659 1.00 52.26 ? 77 GLN A CB 1 ATOM 486 C CG . GLN A 1 77 ? -73.811 25.740 265.468 1.00 57.76 ? 77 GLN A CG 1 ATOM 487 C CD . GLN A 1 77 ? -73.522 26.405 264.131 1.00 73.81 ? 77 GLN A CD 1 ATOM 488 O OE1 . GLN A 1 77 ? -72.858 27.440 264.067 1.00 87.98 ? 77 GLN A OE1 1 ATOM 489 N NE2 . GLN A 1 77 ? -74.021 25.808 263.054 1.00 57.83 ? 77 GLN A NE2 1 ATOM 490 N N . GLN A 1 78 ? -70.879 28.533 267.662 1.00 35.01 ? 78 GLN A N 1 ATOM 491 C CA . GLN A 1 78 ? -70.227 29.423 268.614 1.00 31.78 ? 78 GLN A CA 1 ATOM 492 C C . GLN A 1 78 ? -71.198 29.909 269.684 1.00 29.16 ? 78 GLN A C 1 ATOM 493 O O . GLN A 1 78 ? -72.351 30.242 269.397 1.00 30.90 ? 78 GLN A O 1 ATOM 494 C CB . GLN A 1 78 ? -69.625 30.619 267.880 1.00 33.43 ? 78 GLN A CB 1 ATOM 495 C CG . GLN A 1 78 ? -68.564 31.366 268.664 1.00 31.23 ? 78 GLN A CG 1 ATOM 496 C CD . GLN A 1 78 ? -68.262 32.726 268.072 1.00 37.31 ? 78 GLN A CD 1 ATOM 497 O OE1 . GLN A 1 78 ? -68.930 33.712 268.382 1.00 53.90 ? 78 GLN A OE1 1 ATOM 498 N NE2 . GLN A 1 78 ? -67.260 32.784 267.204 1.00 45.39 ? 78 GLN A NE2 1 ATOM 499 N N . VAL A 1 79 ? -70.720 29.946 270.929 1.00 30.14 ? 79 VAL A N 1 ATOM 500 C CA . VAL A 1 79 ? -71.497 30.472 272.048 1.00 29.19 ? 79 VAL A CA 1 ATOM 501 C C . VAL A 1 79 ? -70.617 31.352 272.927 1.00 38.53 ? 79 VAL A C 1 ATOM 502 O O . VAL A 1 79 ? -71.100 31.966 273.885 1.00 53.92 ? 79 VAL A O 1 ATOM 503 C CB . VAL A 1 79 ? -72.132 29.344 272.885 1.00 27.15 ? 79 VAL A CB 1 ATOM 504 C CG1 . VAL A 1 79 ? -73.016 28.455 272.024 1.00 44.85 ? 79 VAL A CG1 1 ATOM 505 C CG2 . VAL A 1 79 ? -71.056 28.528 273.581 1.00 29.04 ? 79 VAL A CG2 1 ATOM 506 N N . TRP A 1 80 ? -69.323 31.420 272.616 1.00 31.52 ? 80 TRP A N 1 ATOM 507 C CA . TRP A 1 80 ? -68.396 32.187 273.437 1.00 27.97 ? 80 TRP A CA 1 ATOM 508 C C . TRP A 1 80 ? -67.114 32.436 272.656 1.00 27.93 ? 80 TRP A C 1 ATOM 509 O O . TRP A 1 80 ? -66.744 31.652 271.779 1.00 41.55 ? 80 TRP A O 1 ATOM 510 C CB . TRP A 1 80 ? -68.084 31.461 274.753 1.00 27.43 ? 80 TRP A CB 1 ATOM 511 C CG . TRP A 1 80 ? -67.232 32.248 275.707 1.00 26.90 ? 80 TRP A CG 1 ATOM 512 C CD1 . TRP A 1 80 ? -67.666 33.108 276.673 1.00 37.89 ? 80 TRP A CD1 1 ATOM 513 C CD2 . TRP A 1 80 ? -65.802 32.239 275.792 1.00 25.72 ? 80 TRP A CD2 1 ATOM 514 N NE1 . TRP A 1 80 ? -66.596 33.638 277.351 1.00 28.46 ? 80 TRP A NE1 1 ATOM 515 C CE2 . TRP A 1 80 ? -65.440 33.121 276.829 1.00 25.95 ? 80 TRP A CE2 1 ATOM 516 C CE3 . TRP A 1 80 ? -64.792 31.573 275.091 1.00 29.88 ? 80 TRP A CE3 1 ATOM 517 C CZ2 . TRP A 1 80 ? -64.112 33.354 277.182 1.00 30.18 ? 80 TRP A CZ2 1 ATOM 518 C CZ3 . TRP A 1 80 ? -63.475 31.806 275.443 1.00 27.60 ? 80 TRP A CZ3 1 ATOM 519 C CH2 . TRP A 1 80 ? -63.147 32.688 276.479 1.00 28.49 ? 80 TRP A CH2 1 ATOM 520 N N . LYS A 1 81 ? -66.447 33.541 272.985 1.00 30.72 ? 81 LYS A N 1 ATOM 521 C CA . LYS A 1 81 ? -65.129 33.839 272.444 1.00 29.83 ? 81 LYS A CA 1 ATOM 522 C C . LYS A 1 81 ? -64.425 34.806 273.384 1.00 28.60 ? 81 LYS A C 1 ATOM 523 O O . LYS A 1 81 ? -65.070 35.583 274.092 1.00 29.71 ? 81 LYS A O 1 ATOM 524 C CB . LYS A 1 81 ? -65.204 34.424 271.028 1.00 32.26 ? 81 LYS A CB 1 ATOM 525 C CG . LYS A 1 81 ? -65.837 35.801 270.940 1.00 38.06 ? 81 LYS A CG 1 ATOM 526 C CD . LYS A 1 81 ? -65.472 36.476 269.628 1.00 48.95 ? 81 LYS A CD 1 ATOM 527 C CE . LYS A 1 81 ? -66.080 37.863 269.525 1.00 60.23 ? 81 LYS A CE 1 ATOM 528 N NZ . LYS A 1 81 ? -67.564 37.813 269.420 1.00 92.76 ? 81 LYS A NZ 1 ATOM 529 N N . GLY A 1 82 ? -63.095 34.742 273.388 1.00 27.81 ? 82 GLY A N 1 ATOM 530 C CA . GLY A 1 82 ? -62.303 35.602 274.248 1.00 33.96 ? 82 GLY A CA 1 ATOM 531 C C . GLY A 1 82 ? -60.811 35.363 274.141 1.00 37.28 ? 82 GLY A C 1 ATOM 532 O O . GLY A 1 82 ? -60.306 35.021 273.068 1.00 55.85 ? 82 GLY A O 1 ATOM 533 N N . ASP A 1 83 ? -60.094 35.540 275.249 1.00 35.76 ? 83 ASP A N 1 ATOM 534 C CA . ASP A 1 83 ? -58.650 35.354 275.276 1.00 37.74 ? 83 ASP A CA 1 ATOM 535 C C . ASP A 1 83 ? -58.315 33.912 275.635 1.00 36.07 ? 83 ASP A C 1 ATOM 536 O O . ASP A 1 83 ? -58.855 33.363 276.602 1.00 38.06 ? 83 ASP A O 1 ATOM 537 C CB . ASP A 1 83 ? -58.000 36.309 276.278 1.00 47.11 ? 83 ASP A CB 1 ATOM 538 C CG . ASP A 1 83 ? -58.462 37.740 276.102 1.00 66.25 ? 83 ASP A CG 1 ATOM 539 O OD1 . ASP A 1 83 ? -59.273 37.995 275.186 1.00 72.08 ? 83 ASP A OD1 1 ATOM 540 O OD2 . ASP A 1 83 ? -58.015 38.612 276.876 1.00 56.17 ? 83 ASP A OD2 1 ATOM 541 N N . ALA A 1 84 ? -57.421 33.304 274.854 1.00 35.09 ? 84 ALA A N 1 ATOM 542 C CA . ALA A 1 84 ? -56.978 31.945 275.134 1.00 30.78 ? 84 ALA A CA 1 ATOM 543 C C . ALA A 1 84 ? -56.000 31.877 276.297 1.00 32.56 ? 84 ALA A C 1 ATOM 544 O O . ALA A 1 84 ? -55.793 30.792 276.851 1.00 32.14 ? 84 ALA A O 1 ATOM 545 C CB . ALA A 1 84 ? -56.339 31.332 273.887 1.00 33.90 ? 84 ALA A CB 1 ATOM 546 N N . GLU A 1 85 ? -55.393 33.005 276.674 1.00 38.99 ? 85 GLU A N 1 ATOM 547 C CA . GLU A 1 85 ? -54.498 33.016 277.826 1.00 38.44 ? 85 GLU A CA 1 ATOM 548 C C . GLU A 1 85 ? -55.252 32.749 279.120 1.00 37.40 ? 85 GLU A C 1 ATOM 549 O O . GLU A 1 85 ? -54.689 32.173 280.058 1.00 48.97 ? 85 GLU A O 1 ATOM 550 C CB . GLU A 1 85 ? -53.763 34.356 277.918 1.00 40.80 ? 85 GLU A CB 1 ATOM 551 C CG . GLU A 1 85 ? -52.869 34.690 276.730 1.00 42.33 ? 85 GLU A CG 1 ATOM 552 C CD . GLU A 1 85 ? -53.640 35.205 275.529 1.00 51.46 ? 85 GLU A CD 1 ATOM 553 O OE1 . GLU A 1 85 ? -54.872 35.382 275.637 1.00 77.74 ? 85 GLU A OE1 1 ATOM 554 O OE2 . GLU A 1 85 ? -53.012 35.433 274.474 1.00 51.76 ? 85 GLU A OE2 1 ATOM 555 N N . SER A 1 86 ? -56.521 33.158 279.189 1.00 40.09 ? 86 SER A N 1 ATOM 556 C CA . SER A 1 86 ? -57.297 32.974 280.409 1.00 40.18 ? 86 SER A CA 1 ATOM 557 C C . SER A 1 86 ? -57.572 31.504 280.691 1.00 36.39 ? 86 SER A C 1 ATOM 558 O O . SER A 1 86 ? -57.670 31.109 281.858 1.00 36.62 ? 86 SER A O 1 ATOM 559 C CB . SER A 1 86 ? -58.611 33.748 280.312 1.00 35.79 ? 86 SER A CB 1 ATOM 560 O OG . SER A 1 86 ? -59.302 33.422 279.119 1.00 32.23 ? 86 SER A OG 1 ATOM 561 N N . LYS A 1 87 ? -57.697 30.686 279.643 1.00 34.17 ? 87 LYS A N 1 ATOM 562 C CA . LYS A 1 87 ? -58.008 29.262 279.775 1.00 33.42 ? 87 LYS A CA 1 ATOM 563 C C . LYS A 1 87 ? -59.286 29.035 280.576 1.00 32.11 ? 87 LYS A C 1 ATOM 564 O O . LYS A 1 87 ? -59.431 28.022 281.264 1.00 39.25 ? 87 LYS A O 1 ATOM 565 C CB . LYS A 1 87 ? -56.841 28.490 280.399 1.00 47.41 ? 87 LYS A CB 1 ATOM 566 C CG . LYS A 1 87 ? -55.548 28.560 279.604 1.00 33.80 ? 87 LYS A CG 1 ATOM 567 C CD . LYS A 1 87 ? -54.459 27.728 280.261 1.00 30.25 ? 87 LYS A CD 1 ATOM 568 C CE . LYS A 1 87 ? -53.168 27.777 279.464 1.00 34.86 ? 87 LYS A CE 1 ATOM 569 N NZ . LYS A 1 87 ? -52.116 26.908 280.060 1.00 34.13 ? 87 LYS A NZ 1 ATOM 570 N N . ARG A 1 88 ? -60.222 29.978 280.492 1.00 33.09 ? 88 ARG A N 1 ATOM 571 C CA . ARG A 1 88 ? -61.468 29.902 281.238 1.00 33.68 ? 88 ARG A CA 1 ATOM 572 C C . ARG A 1 88 ? -62.560 30.600 280.443 1.00 31.99 ? 88 ARG A C 1 ATOM 573 O O . ARG A 1 88 ? -62.302 31.570 279.725 1.00 30.16 ? 88 ARG A O 1 ATOM 574 C CB . ARG A 1 88 ? -61.333 30.539 282.626 1.00 39.23 ? 88 ARG A CB 1 ATOM 575 C CG . ARG A 1 88 ? -62.537 30.334 283.531 1.00 32.50 ? 88 ARG A CG 1 ATOM 576 C CD . ARG A 1 88 ? -62.456 31.221 284.758 1.00 35.38 ? 88 ARG A CD 1 ATOM 577 N NE . ARG A 1 88 ? -63.434 30.848 285.775 1.00 37.27 ? 88 ARG A NE 1 ATOM 578 C CZ . ARG A 1 88 ? -63.463 31.355 287.003 1.00 47.70 ? 88 ARG A CZ 1 ATOM 579 N NH1 . ARG A 1 88 ? -62.565 32.259 287.371 1.00 56.30 ? 88 ARG A NH1 1 ATOM 580 N NH2 . ARG A 1 88 ? -64.389 30.959 287.866 1.00 43.24 ? 88 ARG A NH2 1 ATOM 581 N N . ALA A 1 89 ? -63.784 30.096 280.578 1.00 33.68 ? 89 ALA A N 1 ATOM 582 C CA . ALA A 1 89 ? -64.931 30.686 279.907 1.00 30.92 ? 89 ALA A CA 1 ATOM 583 C C . ALA A 1 89 ? -66.174 30.450 280.750 1.00 29.47 ? 89 ALA A C 1 ATOM 584 O O . ALA A 1 89 ? -66.338 29.380 281.343 1.00 30.73 ? 89 ALA A O 1 ATOM 585 C CB . ALA A 1 89 ? -65.122 30.103 278.503 1.00 27.82 ? 89 ALA A CB 1 ATOM 586 N N . THR A 1 90 ? -67.040 31.459 280.803 1.00 27.64 ? 90 THR A N 1 ATOM 587 C CA . THR A 1 90 ? -68.310 31.378 281.514 1.00 24.35 ? 90 THR A CA 1 ATOM 588 C C . THR A 1 90 ? -69.420 31.737 280.539 1.00 23.60 ? 90 THR A C 1 ATOM 589 O O . THR A 1 90 ? -69.436 32.847 279.997 1.00 26.18 ? 90 THR A O 1 ATOM 590 C CB . THR A 1 90 ? -68.332 32.313 282.726 1.00 24.22 ? 90 THR A CB 1 ATOM 591 O OG1 . THR A 1 90 ? -67.247 31.984 283.603 1.00 28.10 ? 90 THR A OG1 1 ATOM 592 C CG2 . THR A 1 90 ? -69.644 32.178 283.479 1.00 26.34 ? 90 THR A CG2 1 ATOM 593 N N . ILE A 1 91 ? -70.339 30.803 280.314 1.00 22.51 ? 91 ILE A N 1 ATOM 594 C CA . ILE A 1 91 ? -71.392 30.952 279.316 1.00 25.63 ? 91 ILE A CA 1 ATOM 595 C C . ILE A 1 91 ? -72.732 31.056 280.028 1.00 24.46 ? 91 ILE A C 1 ATOM 596 O O . ILE A 1 91 ? -73.050 30.234 280.896 1.00 22.80 ? 91 ILE A O 1 ATOM 597 C CB . ILE A 1 91 ? -71.392 29.784 278.315 1.00 25.70 ? 91 ILE A CB 1 ATOM 598 C CG1 . ILE A 1 91 ? -70.025 29.653 277.639 1.00 27.14 ? 91 ILE A CG1 1 ATOM 599 C CG2 . ILE A 1 91 ? -72.478 29.982 277.271 1.00 26.20 ? 91 ILE A CG2 1 ATOM 600 C CD1 . ILE A 1 91 ? -69.120 28.617 278.274 1.00 25.72 ? 91 ILE A CD1 1 ATOM 601 N N . LYS A 1 92 ? -73.515 32.065 279.656 1.00 28.05 ? 92 LYS A N 1 ATOM 602 C CA . LYS A 1 92 ? -74.850 32.253 280.207 1.00 24.53 ? 92 LYS A CA 1 ATOM 603 C C . LYS A 1 92 ? -75.842 31.388 279.438 1.00 22.47 ? 92 LYS A C 1 ATOM 604 O O . LYS A 1 92 ? -75.944 31.493 278.211 1.00 26.87 ? 92 LYS A O 1 ATOM 605 C CB . LYS A 1 92 ? -75.249 33.724 280.132 1.00 26.10 ? 92 LYS A CB 1 ATOM 606 C CG . LYS A 1 92 ? -76.624 34.029 280.695 1.00 31.24 ? 92 LYS A CG 1 ATOM 607 C CD . LYS A 1 92 ? -76.975 35.494 280.511 1.00 26.35 ? 92 LYS A CD 1 ATOM 608 C CE . LYS A 1 92 ? -77.093 35.848 279.037 1.00 26.28 ? 92 LYS A CE 1 ATOM 609 N NZ . LYS A 1 92 ? -77.401 37.289 278.832 1.00 34.64 ? 92 LYS A NZ 1 ATOM 610 N N . VAL A 1 93 ? -76.570 30.537 280.155 1.00 24.20 ? 93 VAL A N 1 ATOM 611 C CA . VAL A 1 93 ? -77.579 29.663 279.567 1.00 22.87 ? 93 VAL A CA 1 ATOM 612 C C . VAL A 1 93 ? -78.915 29.969 280.228 1.00 23.75 ? 93 VAL A C 1 ATOM 613 O O . VAL A 1 93 ? -78.998 30.052 281.458 1.00 22.78 ? 93 VAL A O 1 ATOM 614 C CB . VAL A 1 93 ? -77.209 28.177 279.730 1.00 23.15 ? 93 VAL A CB 1 ATOM 615 C CG1 . VAL A 1 93 ? -78.347 27.290 279.254 1.00 24.22 ? 93 VAL A CG1 1 ATOM 616 C CG2 . VAL A 1 93 ? -75.931 27.863 278.967 1.00 24.86 ? 93 VAL A CG2 1 ATOM 617 N N . LEU A 1 94 ? -79.956 30.140 279.410 1.00 28.12 ? 94 LEU A N 1 ATOM 618 C CA . LEU A 1 94 ? -81.275 30.510 279.903 1.00 27.09 ? 94 LEU A CA 1 ATOM 619 C C . LEU A 1 94 ? -82.305 29.394 279.822 1.00 27.75 ? 94 LEU A C 1 ATOM 620 O O . LEU A 1 94 ? -83.321 29.468 280.520 1.00 30.20 ? 94 LEU A O 1 ATOM 621 C CB . LEU A 1 94 ? -81.812 31.727 279.134 1.00 29.07 ? 94 LEU A CB 1 ATOM 622 C CG . LEU A 1 94 ? -81.571 33.121 279.720 1.00 24.99 ? 94 LEU A CG 1 ATOM 623 C CD1 . LEU A 1 94 ? -80.127 33.306 280.155 1.00 27.21 ? 94 LEU A CD1 1 ATOM 624 C CD2 . LEU A 1 94 ? -81.969 34.191 278.714 1.00 35.58 ? 94 LEU A CD2 1 ATOM 625 N N . VAL A 1 95 ? -82.080 28.375 278.998 1.00 26.91 ? 95 VAL A N 1 ATOM 626 C CA . VAL A 1 95 ? -83.051 27.308 278.801 1.00 25.87 ? 95 VAL A CA 1 ATOM 627 C C . VAL A 1 95 ? -82.418 25.977 279.176 1.00 28.39 ? 95 VAL A C 1 ATOM 628 O O . VAL A 1 95 ? -81.203 25.787 279.065 1.00 25.29 ? 95 VAL A O 1 ATOM 629 C CB . VAL A 1 95 ? -83.573 27.273 277.349 1.00 20.23 ? 95 VAL A CB 1 ATOM 630 C CG1 . VAL A 1 95 ? -84.446 28.484 277.073 1.00 30.28 ? 95 VAL A CG1 1 ATOM 631 C CG2 . VAL A 1 95 ? -82.411 27.214 276.371 1.00 26.46 ? 95 VAL A CG2 1 ATOM 632 N N . SER A 1 96 ? -83.260 25.050 279.624 1.00 33.18 ? 96 SER A N 1 ATOM 633 C CA . SER A 1 96 ? -82.792 23.726 279.998 1.00 29.88 ? 96 SER A CA 1 ATOM 634 C C . SER A 1 96 ? -82.442 22.908 278.759 1.00 29.28 ? 96 SER A C 1 ATOM 635 O O . SER A 1 96 ? -82.838 23.226 277.634 1.00 37.93 ? 96 SER A O 1 ATOM 636 C CB . SER A 1 96 ? -83.854 22.998 280.820 1.00 26.76 ? 96 SER A CB 1 ATOM 637 O OG . SER A 1 96 ? -85.127 23.104 280.208 1.00 27.42 ? 96 SER A OG 1 ATOM 638 N N . GLY A 1 97 ? -81.692 21.844 278.978 1.00 25.96 ? 97 GLY A N 1 ATOM 639 C CA . GLY A 1 97 ? -81.306 20.956 277.898 1.00 28.24 ? 97 GLY A CA 1 ATOM 640 C C . GLY A 1 97 ? -79.918 20.398 278.121 1.00 29.96 ? 97 GLY A C 1 ATOM 641 O O . GLY A 1 97 ? -79.175 20.827 279.002 1.00 26.81 ? 97 GLY A O 1 ATOM 642 N N . GLN A 1 98 ? -79.577 19.416 277.291 1.00 31.03 ? 98 GLN A N 1 ATOM 643 C CA . GLN A 1 98 ? -78.279 18.760 277.322 1.00 27.12 ? 98 GLN A CA 1 ATOM 644 C C . GLN A 1 98 ? -77.561 18.998 276.002 1.00 25.74 ? 98 GLN A C 1 ATOM 645 O O . GLN A 1 98 ? -78.177 18.953 274.932 1.00 25.77 ? 98 GLN A O 1 ATOM 646 C CB . GLN A 1 98 ? -78.427 17.259 277.582 1.00 27.13 ? 98 GLN A CB 1 ATOM 647 C CG . GLN A 1 98 ? -79.060 16.928 278.925 1.00 43.85 ? 98 GLN A CG 1 ATOM 648 C CD . GLN A 1 98 ? -79.290 15.443 279.110 1.00 50.47 ? 98 GLN A CD 1 ATOM 649 O OE1 . GLN A 1 98 ? -79.370 14.692 278.139 1.00 52.20 ? 98 GLN A OE1 1 ATOM 650 N NE2 . GLN A 1 98 ? -79.393 15.009 280.361 1.00 35.10 ? 98 GLN A NE2 1 ATOM 651 N N . PHE A 1 99 ? -76.257 19.252 276.080 1.00 23.04 ? 99 PHE A N 1 ATOM 652 C CA . PHE A 1 99 ? -75.479 19.586 274.896 1.00 20.76 ? 99 PHE A CA 1 ATOM 653 C C . PHE A 1 99 ? -74.012 19.290 275.162 1.00 18.69 ? 99 PHE A C 1 ATOM 654 O O . PHE A 1 99 ? -73.561 19.267 276.311 1.00 20.59 ? 99 PHE A O 1 ATOM 655 C CB . PHE A 1 99 ? -75.674 21.054 274.500 1.00 25.59 ? 99 PHE A CB 1 ATOM 656 C CG . PHE A 1 99 ? -75.575 22.012 275.654 1.00 26.87 ? 99 PHE A CG 1 ATOM 657 C CD1 . PHE A 1 99 ? -74.341 22.442 276.114 1.00 25.68 ? 99 PHE A CD1 1 ATOM 658 C CD2 . PHE A 1 99 ? -76.717 22.481 276.281 1.00 33.66 ? 99 PHE A CD2 1 ATOM 659 C CE1 . PHE A 1 99 ? -74.250 23.321 277.176 1.00 24.22 ? 99 PHE A CE1 1 ATOM 660 C CE2 . PHE A 1 99 ? -76.632 23.360 277.343 1.00 26.42 ? 99 PHE A CE2 1 ATOM 661 C CZ . PHE A 1 99 ? -75.396 23.781 277.791 1.00 23.96 ? 99 PHE A CZ 1 ATOM 662 N N . ASN A 1 100 ? -73.272 19.067 274.079 1.00 19.11 ? 100 ASN A N 1 ATOM 663 C CA . ASN A 1 100 ? -71.841 18.808 274.154 1.00 18.53 ? 100 ASN A CA 1 ATOM 664 C C . ASN A 1 100 ? -71.075 20.121 274.067 1.00 22.67 ? 100 ASN A C 1 ATOM 665 O O . ASN A 1 100 ? -71.300 20.921 273.153 1.00 23.16 ? 100 ASN A O 1 ATOM 666 C CB . ASN A 1 100 ? -71.399 17.865 273.035 1.00 15.99 ? 100 ASN A CB 1 ATOM 667 C CG . ASN A 1 100 ? -72.003 16.482 273.165 1.00 14.15 ? 100 ASN A CG 1 ATOM 668 O OD1 . ASN A 1 100 ? -72.310 16.026 274.267 1.00 16.87 ? 100 ASN A OD1 1 ATOM 669 N ND2 . ASN A 1 100 ? -72.176 15.804 272.037 1.00 12.97 ? 100 ASN A ND2 1 ATOM 670 N N . MET A 1 101 ? -70.170 20.336 275.017 1.00 22.76 ? 101 MET A N 1 ATOM 671 C CA . MET A 1 101 ? -69.358 21.542 275.079 1.00 21.55 ? 101 MET A CA 1 ATOM 672 C C . MET A 1 101 ? -67.919 21.216 274.708 1.00 21.97 ? 101 MET A C 1 ATOM 673 O O . MET A 1 101 ? -67.319 20.294 275.273 1.00 21.12 ? 101 MET A O 1 ATOM 674 C CB . MET A 1 101 ? -69.415 22.173 276.471 1.00 21.17 ? 101 MET A CB 1 ATOM 675 C CG . MET A 1 101 ? -68.454 23.331 276.659 1.00 21.59 ? 101 MET A CG 1 ATOM 676 S SD . MET A 1 101 ? -68.632 24.105 278.273 1.00 12.72 ? 101 MET A SD 1 ATOM 677 C CE . MET A 1 101 ? -68.268 22.724 279.347 1.00 23.56 ? 101 MET A CE 1 ATOM 678 N N . ARG A 1 102 ? -67.371 21.974 273.762 1.00 25.24 ? 102 ARG A N 1 ATOM 679 C CA . ARG A 1 102 ? -65.992 21.823 273.330 1.00 23.51 ? 102 ARG A CA 1 ATOM 680 C C . ARG A 1 102 ? -65.298 23.176 273.364 1.00 23.97 ? 102 ARG A C 1 ATOM 681 O O . ARG A 1 102 ? -65.927 24.220 273.176 1.00 24.05 ? 102 ARG A O 1 ATOM 682 C CB . ARG A 1 102 ? -65.901 21.236 271.915 1.00 21.77 ? 102 ARG A CB 1 ATOM 683 C CG . ARG A 1 102 ? -66.349 19.793 271.799 1.00 21.85 ? 102 ARG A CG 1 ATOM 684 C CD . ARG A 1 102 ? -66.409 19.361 270.344 1.00 28.09 ? 102 ARG A CD 1 ATOM 685 N NE . ARG A 1 102 ? -65.686 18.115 270.110 1.00 36.24 ? 102 ARG A NE 1 ATOM 686 C CZ . ARG A 1 102 ? -65.756 17.410 268.986 1.00 58.30 ? 102 ARG A CZ 1 ATOM 687 N NH1 . ARG A 1 102 ? -66.519 17.829 267.985 1.00 50.08 ? 102 ARG A NH1 1 ATOM 688 N NH2 . ARG A 1 102 ? -65.063 16.287 268.861 1.00 50.10 ? 102 ARG A NH2 1 ATOM 689 N N . VAL A 1 103 ? -63.991 23.146 273.608 1.00 24.26 ? 103 VAL A N 1 ATOM 690 C CA . VAL A 1 103 ? -63.144 24.330 273.531 1.00 25.59 ? 103 VAL A CA 1 ATOM 691 C C . VAL A 1 103 ? -62.365 24.268 272.227 1.00 25.81 ? 103 VAL A C 1 ATOM 692 O O . VAL A 1 103 ? -61.743 23.245 271.914 1.00 25.04 ? 103 VAL A O 1 ATOM 693 C CB . VAL A 1 103 ? -62.198 24.423 274.740 1.00 30.41 ? 103 VAL A CB 1 ATOM 694 C CG1 . VAL A 1 103 ? -61.305 25.648 274.620 1.00 26.57 ? 103 VAL A CG1 1 ATOM 695 C CG2 . VAL A 1 103 ? -62.996 24.470 276.031 1.00 33.18 ? 103 VAL A CG2 1 ATOM 696 N N . LYS A 1 104 ? -62.402 25.355 271.463 1.00 26.60 ? 104 LYS A N 1 ATOM 697 C CA . LYS A 1 104 ? -61.779 25.416 270.143 1.00 26.49 ? 104 LYS A CA 1 ATOM 698 C C . LYS A 1 104 ? -60.798 26.583 270.121 1.00 28.05 ? 104 LYS A C 1 ATOM 699 O O . LYS A 1 104 ? -61.208 27.746 270.045 1.00 27.81 ? 104 LYS A O 1 ATOM 700 C CB . LYS A 1 104 ? -62.836 25.552 269.051 1.00 26.50 ? 104 LYS A CB 1 ATOM 701 C CG . LYS A 1 104 ? -62.290 25.477 267.635 1.00 26.51 ? 104 LYS A CG 1 ATOM 702 C CD . LYS A 1 104 ? -63.419 25.420 266.618 1.00 26.59 ? 104 LYS A CD 1 ATOM 703 C CE . LYS A 1 104 ? -62.889 25.474 265.196 1.00 26.81 ? 104 LYS A CE 1 ATOM 704 N NZ . LYS A 1 104 ? -63.985 25.485 264.190 1.00 27.14 ? 104 LYS A NZ 1 ATOM 705 N N . LEU A 1 105 ? -59.507 26.270 270.187 1.00 28.57 ? 105 LEU A N 1 ATOM 706 C CA . LEU A 1 105 ? -58.455 27.272 270.093 1.00 29.71 ? 105 LEU A CA 1 ATOM 707 C C . LEU A 1 105 ? -58.063 27.453 268.632 1.00 31.41 ? 105 LEU A C 1 ATOM 708 O O . LEU A 1 105 ? -57.736 26.480 267.947 1.00 31.22 ? 105 LEU A O 1 ATOM 709 C CB . LEU A 1 105 ? -57.239 26.860 270.923 1.00 31.29 ? 105 LEU A CB 1 ATOM 710 C CG . LEU A 1 105 ? -57.498 26.495 272.387 1.00 30.02 ? 105 LEU A CG 1 ATOM 711 C CD1 . LEU A 1 105 ? -56.198 26.144 273.094 1.00 46.55 ? 105 LEU A CD1 1 ATOM 712 C CD2 . LEU A 1 105 ? -58.210 27.624 273.107 1.00 27.14 ? 105 LEU A CD2 1 ATOM 713 N N . CYS A 1 106 ? -58.097 28.697 268.160 1.00 32.40 ? 106 CYS A N 1 ATOM 714 C CA . CYS A 1 106 ? -57.826 29.007 266.765 1.00 36.47 ? 106 CYS A CA 1 ATOM 715 C C . CYS A 1 106 ? -56.744 30.072 266.667 1.00 39.34 ? 106 CYS A C 1 ATOM 716 O O . CYS A 1 106 ? -56.584 30.904 267.565 1.00 52.66 ? 106 CYS A O 1 ATOM 717 C CB . CYS A 1 106 ? -59.085 29.504 266.044 1.00 34.61 ? 106 CYS A CB 1 ATOM 718 S SG . CYS A 1 106 ? -60.342 28.253 265.699 1.00 36.28 ? 106 CYS A SG 1 ATOM 719 N N . ASN A 1 107 ? -56.006 30.041 265.562 1.00 40.19 ? 107 ASN A N 1 ATOM 720 C CA . ASN A 1 107 ? -55.028 31.079 265.257 1.00 49.06 ? 107 ASN A CA 1 ATOM 721 C C . ASN A 1 107 ? -54.811 31.099 263.744 1.00 48.41 ? 107 ASN A C 1 ATOM 722 O O . ASN A 1 107 ? -55.658 30.620 262.981 1.00 44.80 ? 107 ASN A O 1 ATOM 723 C CB . ASN A 1 107 ? -53.730 30.858 266.054 1.00 51.68 ? 107 ASN A CB 1 ATOM 724 C CG . ASN A 1 107 ? -53.030 29.561 265.695 1.00 43.25 ? 107 ASN A CG 1 ATOM 725 O OD1 . ASN A 1 107 ? -53.503 28.789 264.862 1.00 44.12 ? 107 ASN A OD1 1 ATOM 726 N ND2 . ASN A 1 107 ? -51.891 29.314 266.330 1.00 45.14 ? 107 ASN A ND2 1 ATOM 727 N N . GLU A 1 108 ? -53.672 31.647 263.312 1.00 50.80 ? 108 GLU A N 1 ATOM 728 C CA . GLU A 1 108 ? -53.400 31.766 261.883 1.00 43.96 ? 108 GLU A CA 1 ATOM 729 C C . GLU A 1 108 ? -53.193 30.402 261.237 1.00 43.06 ? 108 GLU A C 1 ATOM 730 O O . GLU A 1 108 ? -53.601 30.186 260.090 1.00 45.37 ? 108 GLU A O 1 ATOM 731 C CB . GLU A 1 108 ? -52.180 32.659 261.658 1.00 42.02 ? 108 GLU A CB 1 ATOM 732 C CG . GLU A 1 108 ? -51.998 33.141 260.225 1.00 51.33 ? 108 GLU A CG 1 ATOM 733 C CD . GLU A 1 108 ? -51.247 32.146 259.360 1.00 41.22 ? 108 GLU A CD 1 ATOM 734 O OE1 . GLU A 1 108 ? -51.615 31.987 258.177 1.00 44.45 ? 108 GLU A OE1 1 ATOM 735 O OE2 . GLU A 1 108 ? -50.289 31.523 259.863 1.00 45.73 ? 108 GLU A OE2 1 ATOM 736 N N . ASP A 1 109 ? -52.559 29.473 261.951 1.00 47.53 ? 109 ASP A N 1 ATOM 737 C CA . ASP A 1 109 ? -52.289 28.145 261.412 1.00 48.27 ? 109 ASP A CA 1 ATOM 738 C C . ASP A 1 109 ? -53.587 27.402 261.127 1.00 49.24 ? 109 ASP A C 1 ATOM 739 O O . ASP A 1 109 ? -53.957 27.203 259.965 1.00 41.91 ? 109 ASP A O 1 ATOM 740 C CB . ASP A 1 109 ? -51.422 27.337 262.380 1.00 56.81 ? 109 ASP A CB 1 ATOM 741 C CG . ASP A 1 109 ? -50.357 28.180 263.053 1.00 84.27 ? 109 ASP A CG 1 ATOM 742 O OD1 . ASP A 1 109 ? -49.327 28.468 262.408 1.00 94.76 ? 109 ASP A OD1 1 ATOM 743 O OD2 . ASP A 1 109 ? -50.549 28.551 264.229 1.00 80.97 ? 109 ASP A OD2 1 ATOM 744 N N . GLY A 1 110 ? -54.276 26.993 262.176 1.00 56.99 ? 110 GLY A N 1 ATOM 745 C CA . GLY A 1 110 ? -55.540 26.297 262.042 1.00 43.14 ? 110 GLY A CA 1 ATOM 746 C C . GLY A 1 110 ? -56.307 26.378 263.337 1.00 38.87 ? 110 GLY A C 1 ATOM 747 O O . GLY A 1 110 ? -56.197 27.352 264.085 1.00 48.14 ? 110 GLY A O 1 ATOM 748 N N . CYS A 1 111 ? -57.093 25.340 263.611 1.00 36.67 ? 111 CYS A N 1 ATOM 749 C CA . CYS A 1 111 ? -57.880 25.274 264.833 1.00 32.14 ? 111 CYS A CA 1 ATOM 750 C C . CYS A 1 111 ? -57.781 23.877 265.424 1.00 39.02 ? 111 CYS A C 1 ATOM 751 O O . CYS A 1 111 ? -57.715 22.887 264.690 1.00 36.51 ? 111 CYS A O 1 ATOM 752 C CB . CYS A 1 111 ? -59.349 25.622 264.576 1.00 35.35 ? 111 CYS A CB 1 ATOM 753 S SG . CYS A 1 111 ? -59.663 27.316 264.029 1.00 47.48 ? 111 CYS A SG 1 ATOM 754 N N . SER A 1 112 ? -57.770 23.806 266.751 1.00 35.16 ? 112 SER A N 1 ATOM 755 C CA . SER A 1 112 ? -57.766 22.545 267.477 1.00 30.41 ? 112 SER A CA 1 ATOM 756 C C . SER A 1 112 ? -59.059 22.421 268.269 1.00 26.15 ? 112 SER A C 1 ATOM 757 O O . SER A 1 112 ? -59.564 23.411 268.807 1.00 26.63 ? 112 SER A O 1 ATOM 758 C CB . SER A 1 112 ? -56.561 22.449 268.417 1.00 32.54 ? 112 SER A CB 1 ATOM 759 O OG . SER A 1 112 ? -56.605 23.458 269.411 1.00 34.49 ? 112 SER A OG 1 ATOM 760 N N . VAL A 1 113 ? -59.590 21.204 268.340 1.00 28.72 ? 113 VAL A N 1 ATOM 761 C CA . VAL A 1 113 ? -60.866 20.935 268.992 1.00 24.69 ? 113 VAL A CA 1 ATOM 762 C C . VAL A 1 113 ? -60.627 19.992 270.163 1.00 24.51 ? 113 VAL A C 1 ATOM 763 O O . VAL A 1 113 ? -59.954 18.966 270.014 1.00 26.95 ? 113 VAL A O 1 ATOM 764 C CB . VAL A 1 113 ? -61.890 20.335 268.011 1.00 23.07 ? 113 VAL A CB 1 ATOM 765 C CG1 . VAL A 1 113 ? -63.256 20.230 268.670 1.00 27.76 ? 113 VAL A CG1 1 ATOM 766 C CG2 . VAL A 1 113 ? -61.968 21.174 266.747 1.00 25.45 ? 113 VAL A CG2 1 ATOM 767 N N . SER A 1 114 ? -61.180 20.340 271.320 1.00 23.21 ? 114 SER A N 1 ATOM 768 C CA . SER A 1 114 ? -61.057 19.507 272.503 1.00 23.21 ? 114 SER A CA 1 ATOM 769 C C . SER A 1 114 ? -62.000 18.311 272.414 1.00 22.72 ? 114 SER A C 1 ATOM 770 O O . SER A 1 114 ? -62.906 18.256 271.578 1.00 25.41 ? 114 SER A O 1 ATOM 771 C CB . SER A 1 114 ? -61.357 20.320 273.761 1.00 24.34 ? 114 SER A CB 1 ATOM 772 O OG . SER A 1 114 ? -62.725 20.685 273.812 1.00 23.93 ? 114 SER A OG 1 ATOM 773 N N . ASP A 1 115 ? -61.775 17.338 273.290 1.00 25.48 ? 115 ASP A N 1 ATOM 774 C CA . ASP A 1 115 ? -62.712 16.234 273.411 1.00 26.44 ? 115 ASP A CA 1 ATOM 775 C C . ASP A 1 115 ? -63.994 16.725 274.079 1.00 29.66 ? 115 ASP A C 1 ATOM 776 O O . ASP A 1 115 ? -63.936 17.451 275.076 1.00 28.25 ? 115 ASP A O 1 ATOM 777 C CB . ASP A 1 115 ? -62.103 15.086 274.214 1.00 26.90 ? 115 ASP A CB 1 ATOM 778 C CG . ASP A 1 115 ? -61.141 14.247 273.395 1.00 30.08 ? 115 ASP A CG 1 ATOM 779 O OD1 . ASP A 1 115 ? -61.293 14.206 272.155 1.00 32.29 ? 115 ASP A OD1 1 ATOM 780 O OD2 . ASP A 1 115 ? -60.238 13.623 273.990 1.00 29.17 ? 115 ASP A OD2 1 ATOM 781 N N . PRO A 1 116 ? -65.159 16.356 273.554 1.00 30.62 ? 116 PRO A N 1 ATOM 782 C CA . PRO A 1 116 ? -66.408 16.922 274.071 1.00 28.25 ? 116 PRO A CA 1 ATOM 783 C C . PRO A 1 116 ? -66.788 16.348 275.426 1.00 24.02 ? 116 PRO A C 1 ATOM 784 O O . PRO A 1 116 ? -66.510 15.189 275.744 1.00 24.84 ? 116 PRO A O 1 ATOM 785 C CB . PRO A 1 116 ? -67.437 16.540 273.001 1.00 25.62 ? 116 PRO A CB 1 ATOM 786 C CG . PRO A 1 116 ? -66.880 15.309 272.377 1.00 23.20 ? 116 PRO A CG 1 ATOM 787 C CD . PRO A 1 116 ? -65.385 15.468 272.401 1.00 26.19 ? 116 PRO A CD 1 ATOM 788 N N . VAL A 1 117 ? -67.428 17.192 276.232 1.00 23.09 ? 117 VAL A N 1 ATOM 789 C CA . VAL A 1 117 ? -68.072 16.780 277.470 1.00 25.18 ? 117 VAL A CA 1 ATOM 790 C C . VAL A 1 117 ? -69.537 17.183 277.384 1.00 21.39 ? 117 VAL A C 1 ATOM 791 O O . VAL A 1 117 ? -69.912 18.103 276.654 1.00 19.93 ? 117 VAL A O 1 ATOM 792 C CB . VAL A 1 117 ? -67.408 17.393 278.721 1.00 24.74 ? 117 VAL A CB 1 ATOM 793 C CG1 . VAL A 1 117 ? -65.968 16.921 278.846 1.00 23.74 ? 117 VAL A CG1 1 ATOM 794 C CG2 . VAL A 1 117 ? -67.479 18.911 278.672 1.00 22.79 ? 117 VAL A CG2 1 ATOM 795 N N . LEU A 1 118 ? -70.372 16.477 278.138 1.00 22.47 ? 118 LEU A N 1 ATOM 796 C CA . LEU A 1 118 ? -71.811 16.698 278.118 1.00 22.63 ? 118 LEU A CA 1 ATOM 797 C C . LEU A 1 118 ? -72.227 17.536 279.320 1.00 22.67 ? 118 LEU A C 1 ATOM 798 O O . LEU A 1 118 ? -71.865 17.222 280.459 1.00 22.13 ? 118 LEU A O 1 ATOM 799 C CB . LEU A 1 118 ? -72.566 15.368 278.098 1.00 22.78 ? 118 LEU A CB 1 ATOM 800 C CG . LEU A 1 118 ? -74.087 15.422 278.251 1.00 18.81 ? 118 LEU A CG 1 ATOM 801 C CD1 . LEU A 1 118 ? -74.750 14.460 277.290 1.00 25.75 ? 118 LEU A CD1 1 ATOM 802 C CD2 . LEU A 1 118 ? -74.478 15.077 279.672 1.00 22.76 ? 118 LEU A CD2 1 ATOM 803 N N . VAL A 1 119 ? -72.988 18.596 279.059 1.00 26.15 ? 119 VAL A N 1 ATOM 804 C CA . VAL A 1 119 ? -73.477 19.506 280.087 1.00 24.58 ? 119 VAL A CA 1 ATOM 805 C C . VAL A 1 119 ? -74.982 19.320 280.218 1.00 23.62 ? 119 VAL A C 1 ATOM 806 O O . VAL A 1 119 ? -75.689 19.183 279.213 1.00 28.21 ? 119 VAL A O 1 ATOM 807 C CB . VAL A 1 119 ? -73.133 20.971 279.751 1.00 21.24 ? 119 VAL A CB 1 ATOM 808 C CG1 . VAL A 1 119 ? -73.531 21.893 280.894 1.00 24.27 ? 119 VAL A CG1 1 ATOM 809 C CG2 . VAL A 1 119 ? -71.653 21.109 279.434 1.00 21.80 ? 119 VAL A CG2 1 ATOM 810 N N . LYS A 1 120 ? -75.470 19.311 281.457 1.00 23.12 ? 120 LYS A N 1 ATOM 811 C CA . LYS A 1 120 ? -76.894 19.189 281.743 1.00 25.28 ? 120 LYS A CA 1 ATOM 812 C C . LYS A 1 120 ? -77.374 20.453 282.441 1.00 25.38 ? 120 LYS A C 1 ATOM 813 O O . LYS A 1 120 ? -76.849 20.820 283.498 1.00 23.03 ? 120 LYS A O 1 ATOM 814 C CB . LYS A 1 120 ? -77.189 17.962 282.609 1.00 32.85 ? 120 LYS A CB 1 ATOM 815 C CG . LYS A 1 120 ? -76.636 16.656 282.071 1.00 39.15 ? 120 LYS A CG 1 ATOM 816 C CD . LYS A 1 120 ? -77.091 15.481 282.923 1.00 39.13 ? 120 LYS A CD 1 ATOM 817 C CE . LYS A 1 120 ? -76.227 14.253 282.689 1.00 50.86 ? 120 LYS A CE 1 ATOM 818 N NZ . LYS A 1 120 ? -76.644 13.102 283.536 1.00 56.84 ? 120 LYS A NZ 1 ATOM 819 N N . VAL A 1 121 ? -78.368 21.110 281.852 1.00 25.14 ? 121 VAL A N 1 ATOM 820 C CA . VAL A 1 121 ? -79.030 22.262 282.451 1.00 25.27 ? 121 VAL A CA 1 ATOM 821 C C . VAL A 1 121 ? -80.457 21.847 282.776 1.00 24.51 ? 121 VAL A C 1 ATOM 822 O O . VAL A 1 121 ? -81.226 21.489 281.876 1.00 25.54 ? 121 VAL A O 1 ATOM 823 C CB . VAL A 1 121 ? -79.004 23.483 281.520 1.00 25.88 ? 121 VAL A CB 1 ATOM 824 C CG1 . VAL A 1 121 ? -79.645 24.681 282.202 1.00 31.90 ? 121 VAL A CG1 1 ATOM 825 C CG2 . VAL A 1 121 ? -77.576 23.801 281.105 1.00 25.30 ? 121 VAL A CG2 1 ATOM 826 N N . ALA A 1 122 ? -80.809 21.889 284.056 1.00 25.92 ? 122 ALA A N 1 ATOM 827 C CA . ALA A 1 122 ? -82.092 21.391 284.524 1.00 28.57 ? 122 ALA A CA 1 ATOM 828 C C . ALA A 1 122 ? -83.065 22.534 284.784 1.00 29.33 ? 122 ALA A C 1 ATOM 829 O O . ALA A 1 122 ? -82.673 23.641 285.162 1.00 36.87 ? 122 ALA A O 1 ATOM 830 C CB . ALA A 1 122 ? -81.922 20.560 285.796 1.00 25.91 ? 122 ALA A CB 1 ATOM 831 N N . ASP A 1 123 ? -84.347 22.246 284.576 1.00 28.04 ? 123 ASP A N 1 ATOM 832 C CA . ASP A 1 123 ? -85.420 23.193 284.836 1.00 26.03 ? 123 ASP A CA 1 ATOM 833 C C . ASP A 1 123 ? -86.710 22.402 284.982 1.00 24.46 ? 123 ASP A C 1 ATOM 834 O O . ASP A 1 123 ? -86.788 21.235 284.591 1.00 53.30 ? 123 ASP A O 1 ATOM 835 C CB . ASP A 1 123 ? -85.533 24.239 283.720 1.00 26.41 ? 123 ASP A CB 1 ATOM 836 C CG . ASP A 1 123 ? -86.366 25.438 284.124 1.00 26.09 ? 123 ASP A CG 1 ATOM 837 O OD1 . ASP A 1 123 ? -86.660 25.581 285.329 1.00 37.57 ? 123 ASP A OD1 1 ATOM 838 O OD2 . ASP A 1 123 ? -86.722 26.241 283.236 1.00 21.74 ? 123 ASP A OD2 1 ATOM 839 N N . THR A 1 124 ? -87.727 23.051 285.549 1.00 22.55 ? 124 THR A N 1 ATOM 840 C CA . THR A 1 124 ? -88.977 22.352 285.826 1.00 23.55 ? 124 THR A CA 1 ATOM 841 C C . THR A 1 124 ? -89.807 22.079 284.579 1.00 21.62 ? 124 THR A C 1 ATOM 842 O O . THR A 1 124 ? -90.925 21.569 284.709 1.00 23.20 ? 124 THR A O 1 ATOM 843 C CB . THR A 1 124 ? -89.812 23.138 286.838 1.00 20.84 ? 124 THR A CB 1 ATOM 844 O OG1 . THR A 1 124 ? -90.124 24.432 286.306 1.00 20.57 ? 124 THR A OG1 1 ATOM 845 C CG2 . THR A 1 124 ? -89.046 23.288 288.145 1.00 19.74 ? 124 THR A CG2 1 ATOM 846 N N . ASP A 1 125 ? -89.306 22.395 283.385 1.00 21.05 ? 125 ASP A N 1 ATOM 847 C CA . ASP A 1 125 ? -90.001 22.011 282.164 1.00 27.04 ? 125 ASP A CA 1 ATOM 848 C C . ASP A 1 125 ? -89.664 20.594 281.716 1.00 28.03 ? 125 ASP A C 1 ATOM 849 O O . ASP A 1 125 ? -90.266 20.107 280.753 1.00 29.64 ? 125 ASP A O 1 ATOM 850 C CB . ASP A 1 125 ? -89.689 23.001 281.037 1.00 37.50 ? 125 ASP A CB 1 ATOM 851 C CG . ASP A 1 125 ? -88.200 23.231 280.848 1.00 39.44 ? 125 ASP A CG 1 ATOM 852 O OD1 . ASP A 1 125 ? -87.395 22.372 281.262 1.00 44.72 ? 125 ASP A OD1 1 ATOM 853 O OD2 . ASP A 1 125 ? -87.835 24.276 280.269 1.00 29.25 ? 125 ASP A OD2 1 ATOM 854 N N . GLY A 1 126 ? -88.723 19.929 282.382 1.00 25.56 ? 126 GLY A N 1 ATOM 855 C CA . GLY A 1 126 ? -88.386 18.562 282.043 1.00 29.21 ? 126 GLY A CA 1 ATOM 856 C C . GLY A 1 126 ? -87.492 18.397 280.838 1.00 24.46 ? 126 GLY A C 1 ATOM 857 O O . GLY A 1 126 ? -87.389 17.286 280.308 1.00 22.71 ? 126 GLY A O 1 ATOM 858 N N . GLY A 1 127 ? -86.834 19.467 280.387 1.00 27.74 ? 127 GLY A N 1 ATOM 859 C CA . GLY A 1 127 ? -85.963 19.370 279.228 1.00 26.71 ? 127 GLY A CA 1 ATOM 860 C C . GLY A 1 127 ? -84.749 18.491 279.441 1.00 34.49 ? 127 GLY A C 1 ATOM 861 O O . GLY A 1 127 ? -84.129 18.055 278.465 1.00 37.19 ? 127 GLY A O 1 ATOM 862 N N . HIS A 1 128 ? -84.393 18.222 280.695 1.00 32.80 ? 128 HIS A N 1 ATOM 863 C CA . HIS A 1 128 ? -83.264 17.365 281.025 1.00 26.31 ? 128 HIS A CA 1 ATOM 864 C C . HIS A 1 128 ? -83.679 15.930 281.320 1.00 28.92 ? 128 HIS A C 1 ATOM 865 O O . HIS A 1 128 ? -82.810 15.082 281.547 1.00 44.33 ? 128 HIS A O 1 ATOM 866 C CB . HIS A 1 128 ? -82.511 17.933 282.230 1.00 24.17 ? 128 HIS A CB 1 ATOM 867 C CG . HIS A 1 128 ? -83.283 17.857 283.511 1.00 27.13 ? 128 HIS A CG 1 ATOM 868 N ND1 . HIS A 1 128 ? -84.333 18.702 283.798 1.00 25.22 ? 128 HIS A ND1 1 ATOM 869 C CD2 . HIS A 1 128 ? -83.162 17.031 284.577 1.00 29.30 ? 128 HIS A CD2 1 ATOM 870 C CE1 . HIS A 1 128 ? -84.824 18.403 284.987 1.00 27.93 ? 128 HIS A CE1 1 ATOM 871 N NE2 . HIS A 1 128 ? -84.131 17.392 285.481 1.00 25.72 ? 128 HIS A NE2 1 ATOM 872 N N . LEU A 1 129 ? -84.975 15.638 281.320 1.00 26.69 ? 129 LEU A N 1 ATOM 873 C CA . LEU A 1 129 ? -85.492 14.336 281.708 1.00 23.70 ? 129 LEU A CA 1 ATOM 874 C C . LEU A 1 129 ? -85.939 13.544 280.486 1.00 21.35 ? 129 LEU A C 1 ATOM 875 O O . LEU A 1 129 ? -86.229 14.099 279.423 1.00 19.64 ? 129 LEU A O 1 ATOM 876 C CB . LEU A 1 129 ? -86.664 14.484 282.684 1.00 22.33 ? 129 LEU A CB 1 ATOM 877 C CG . LEU A 1 129 ? -86.336 15.043 284.069 1.00 26.10 ? 129 LEU A CG 1 ATOM 878 C CD1 . LEU A 1 129 ? -87.583 15.083 284.936 1.00 26.36 ? 129 LEU A CD1 1 ATOM 879 C CD2 . LEU A 1 129 ? -85.248 14.217 284.733 1.00 25.26 ? 129 LEU A CD2 1 ATOM 880 N N . ALA A 1 130 ? -85.989 12.224 280.658 1.00 21.66 ? 130 ALA A N 1 ATOM 881 C CA . ALA A 1 130 ? -86.483 11.255 279.698 1.00 22.60 ? 130 ALA A CA 1 ATOM 882 C C . ALA A 1 130 ? -87.933 10.899 280.007 1.00 23.04 ? 130 ALA A C 1 ATOM 883 O O . ALA A 1 130 ? -88.350 10.934 281.169 1.00 27.24 ? 130 ALA A O 1 ATOM 884 C CB . ALA A 1 130 ? -85.628 9.984 279.719 1.00 35.96 ? 130 ALA A CB 1 ATOM 885 N N . PRO A 1 131 ? -88.722 10.564 278.986 1.00 25.52 ? 131 PRO A N 1 ATOM 886 C CA . PRO A 1 131 ? -90.145 10.282 279.214 1.00 21.25 ? 131 PRO A CA 1 ATOM 887 C C . PRO A 1 131 ? -90.357 9.155 280.215 1.00 22.16 ? 131 PRO A C 1 ATOM 888 O O . PRO A 1 131 ? -89.693 8.117 280.165 1.00 18.39 ? 131 PRO A O 1 ATOM 889 C CB . PRO A 1 131 ? -90.651 9.895 277.821 1.00 20.71 ? 131 PRO A CB 1 ATOM 890 C CG . PRO A 1 131 ? -89.755 10.640 276.895 1.00 24.15 ? 131 PRO A CG 1 ATOM 891 C CD . PRO A 1 131 ? -88.398 10.607 277.549 1.00 31.36 ? 131 PRO A CD 1 ATOM 892 N N . LEU A 1 132 ? -91.292 9.377 281.136 1.00 23.47 ? 132 LEU A N 1 ATOM 893 C CA . LEU A 1 132 ? -91.706 8.371 282.114 1.00 22.56 ? 132 LEU A CA 1 ATOM 894 C C . LEU A 1 132 ? -93.039 7.805 281.638 1.00 21.90 ? 132 LEU A C 1 ATOM 895 O O . LEU A 1 132 ? -94.105 8.356 281.913 1.00 21.71 ? 132 LEU A O 1 ATOM 896 C CB . LEU A 1 132 ? -91.810 8.973 283.511 1.00 20.24 ? 132 LEU A CB 1 ATOM 897 C CG . LEU A 1 132 ? -92.344 8.057 284.615 1.00 16.10 ? 132 LEU A CG 1 ATOM 898 C CD1 . LEU A 1 132 ? -91.548 6.763 284.674 1.00 47.85 ? 132 LEU A CD1 1 ATOM 899 C CD2 . LEU A 1 132 ? -92.329 8.765 285.961 1.00 14.89 ? 132 LEU A CD2 1 ATOM 900 N N . GLU A 1 133 ? -92.973 6.694 280.911 1.00 26.24 ? 133 GLU A N 1 ATOM 901 C CA . GLU A 1 133 ? -94.169 6.090 280.344 1.00 28.28 ? 133 GLU A CA 1 ATOM 902 C C . GLU A 1 133 ? -94.901 5.261 281.391 1.00 29.88 ? 133 GLU A C 1 ATOM 903 O O . GLU A 1 133 ? -94.281 4.613 282.239 1.00 32.26 ? 133 GLU A O 1 ATOM 904 C CB . GLU A 1 133 ? -93.809 5.215 279.145 1.00 27.28 ? 133 GLU A CB 1 ATOM 905 C CG . GLU A 1 133 ? -93.105 5.962 278.028 1.00 29.46 ? 133 GLU A CG 1 ATOM 906 C CD . GLU A 1 133 ? -92.773 5.066 276.854 1.00 55.44 ? 133 GLU A CD 1 ATOM 907 O OE1 . GLU A 1 133 ? -91.594 4.676 276.719 1.00 52.93 ? 133 GLU A OE1 1 ATOM 908 O OE2 . GLU A 1 133 ? -93.689 4.752 276.066 1.00 56.88 ? 133 GLU A OE2 1 ATOM 909 N N . TYR A 1 134 ? -96.228 5.285 281.323 1.00 27.33 ? 134 TYR A N 1 ATOM 910 C CA . TYR A 1 134 ? -97.057 4.518 282.243 1.00 27.93 ? 134 TYR A CA 1 ATOM 911 C C . TYR A 1 134 ? -97.157 3.073 281.770 1.00 28.47 ? 134 TYR A C 1 ATOM 912 O O . TYR A 1 134 ? -97.679 2.804 280.683 1.00 32.35 ? 134 TYR A O 1 ATOM 913 C CB . TYR A 1 134 ? -98.446 5.142 282.354 1.00 26.19 ? 134 TYR A CB 1 ATOM 914 C CG . TYR A 1 134 ? -99.437 4.287 283.113 1.00 41.35 ? 134 TYR A CG 1 ATOM 915 C CD1 . TYR A 1 134 ? -99.343 4.134 284.489 1.00 37.78 ? 134 TYR A CD1 1 ATOM 916 C CD2 . TYR A 1 134 ? -100.468 3.633 282.450 1.00 29.37 ? 134 TYR A CD2 1 ATOM 917 C CE1 . TYR A 1 134 ? -100.247 3.352 285.184 1.00 19.81 ? 134 TYR A CE1 1 ATOM 918 C CE2 . TYR A 1 134 ? -101.376 2.851 283.137 1.00 22.24 ? 134 TYR A CE2 1 ATOM 919 C CZ . TYR A 1 134 ? -101.261 2.714 284.504 1.00 20.14 ? 134 TYR A CZ 1 ATOM 920 O OH . TYR A 1 134 ? -102.162 1.936 285.193 1.00 27.00 ? 134 TYR A OH 1 ATOM 921 N N . THR A 1 135 ? -96.652 2.147 282.581 1.00 24.65 ? 135 THR A N 1 ATOM 922 C CA . THR A 1 135 ? -96.854 0.729 282.326 1.00 26.36 ? 135 THR A CA 1 ATOM 923 C C . THR A 1 135 ? -98.225 0.320 282.848 1.00 35.54 ? 135 THR A C 1 ATOM 924 O O . THR A 1 135 ? -98.555 0.571 284.011 1.00 49.92 ? 135 THR A O 1 ATOM 925 C CB . THR A 1 135 ? -95.758 -0.103 282.991 1.00 28.29 ? 135 THR A CB 1 ATOM 926 O OG1 . THR A 1 135 ? -95.937 -0.086 284.412 1.00 37.76 ? 135 THR A OG1 1 ATOM 927 C CG2 . THR A 1 135 ? -94.386 0.462 282.651 1.00 47.53 ? 135 THR A CG2 1 ATOM 928 N N . TRP A 1 136 ? -99.023 -0.304 281.985 1.00 28.16 ? 136 TRP A N 1 ATOM 929 C CA . TRP A 1 136 ? -100.420 -0.579 282.301 1.00 26.79 ? 136 TRP A CA 1 ATOM 930 C C . TRP A 1 136 ? -100.528 -1.566 283.459 1.00 23.04 ? 136 TRP A C 1 ATOM 931 O O . TRP A 1 136 ? -100.103 -2.721 283.347 1.00 30.40 ? 136 TRP A O 1 ATOM 932 C CB . TRP A 1 136 ? -101.139 -1.108 281.064 1.00 24.58 ? 136 TRP A CB 1 ATOM 933 C CG . TRP A 1 136 ? -101.177 -0.106 279.954 1.00 25.28 ? 136 TRP A CG 1 ATOM 934 C CD1 . TRP A 1 136 ? -100.302 -0.001 278.913 1.00 26.67 ? 136 TRP A CD1 1 ATOM 935 C CD2 . TRP A 1 136 ? -102.127 0.952 279.787 1.00 31.09 ? 136 TRP A CD2 1 ATOM 936 N NE1 . TRP A 1 136 ? -100.656 1.049 278.101 1.00 36.19 ? 136 TRP A NE1 1 ATOM 937 C CE2 . TRP A 1 136 ? -101.773 1.651 278.617 1.00 33.37 ? 136 TRP A CE2 1 ATOM 938 C CE3 . TRP A 1 136 ? -103.247 1.373 280.511 1.00 28.24 ? 136 TRP A CE3 1 ATOM 939 C CZ2 . TRP A 1 136 ? -102.496 2.747 278.155 1.00 28.86 ? 136 TRP A CZ2 1 ATOM 940 C CZ3 . TRP A 1 136 ? -103.964 2.459 280.050 1.00 30.34 ? 136 TRP A CZ3 1 ATOM 941 C CH2 . TRP A 1 136 ? -103.587 3.134 278.883 1.00 44.26 ? 136 TRP A CH2 1 ATOM 942 N N . LEU A 1 137 ? -101.104 -1.110 284.566 1.00 20.54 ? 137 LEU A N 1 ATOM 943 C CA . LEU A 1 137 ? -101.272 -1.909 285.769 1.00 22.22 ? 137 LEU A CA 1 ATOM 944 C C . LEU A 1 137 ? -102.748 -2.189 286.017 1.00 22.14 ? 137 LEU A C 1 ATOM 945 O O . LEU A 1 137 ? -103.630 -1.455 285.561 1.00 21.18 ? 137 LEU A O 1 ATOM 946 C CB . LEU A 1 137 ? -100.672 -1.201 286.988 1.00 25.69 ? 137 LEU A CB 1 ATOM 947 C CG . LEU A 1 137 ? -99.227 -0.715 286.879 1.00 30.75 ? 137 LEU A CG 1 ATOM 948 C CD1 . LEU A 1 137 ? -98.809 0.001 288.153 1.00 68.49 ? 137 LEU A CD1 1 ATOM 949 C CD2 . LEU A 1 137 ? -98.291 -1.874 286.578 1.00 56.23 ? 137 LEU A CD2 1 ATOM 950 N N . GLU A 1 138 ? -103.000 -3.268 286.756 1.00 23.18 ? 138 GLU A N 1 ATOM 951 C CA . GLU A 1 138 ? -104.344 -3.673 287.192 1.00 18.50 ? 138 GLU A CA 1 ATOM 952 C C . GLU A 1 138 ? -105.208 -3.877 285.949 1.00 18.59 ? 138 GLU A C 1 ATOM 953 O O . GLU A 1 138 ? -104.790 -4.606 285.035 1.00 19.01 ? 138 GLU A O 1 ATOM 954 C CB . GLU A 1 138 ? -104.870 -2.660 288.201 1.00 17.92 ? 138 GLU A CB 1 ATOM 955 C CG . GLU A 1 138 ? -103.926 -2.390 289.357 1.00 19.19 ? 138 GLU A CG 1 ATOM 956 C CD . GLU A 1 138 ? -104.542 -1.492 290.409 1.00 36.09 ? 138 GLU A CD 1 ATOM 957 O OE1 . GLU A 1 138 ? -105.295 -2.009 291.261 1.00 19.77 ? 138 GLU A OE1 1 ATOM 958 O OE2 . GLU A 1 138 ? -104.278 -0.272 290.385 1.00 38.28 ? 138 GLU A OE2 1 ATOM 959 N N . ASN A 1 139 ? -106.393 -3.272 285.864 1.00 21.12 ? 139 ASN A N 1 ATOM 960 C CA . ASN A 1 139 ? -107.309 -3.490 284.753 1.00 22.92 ? 139 ASN A CA 1 ATOM 961 C C . ASN A 1 139 ? -107.391 -2.294 283.811 1.00 20.80 ? 139 ASN A C 1 ATOM 962 O O . ASN A 1 139 ? -108.288 -2.248 282.963 1.00 24.99 ? 139 ASN A O 1 ATOM 963 C CB . ASN A 1 139 ? -108.702 -3.837 285.283 1.00 22.78 ? 139 ASN A CB 1 ATOM 964 C CG . ASN A 1 139 ? -108.692 -5.044 286.201 1.00 32.14 ? 139 ASN A CG 1 ATOM 965 O OD1 . ASN A 1 139 ? -107.843 -5.927 286.075 1.00 24.24 ? 139 ASN A OD1 1 ATOM 966 N ND2 . ASN A 1 139 ? -109.637 -5.087 287.133 1.00 40.12 ? 139 ASN A ND2 1 ATOM 967 N N . ASN A 1 140 ? -106.484 -1.330 283.938 1.00 18.62 ? 140 ASN A N 1 ATOM 968 C CA . ASN A 1 140 ? -106.481 -0.184 283.039 1.00 23.10 ? 140 ASN A CA 1 ATOM 969 C C . ASN A 1 140 ? -106.082 -0.620 281.635 1.00 24.34 ? 140 ASN A C 1 ATOM 970 O O . ASN A 1 140 ? -105.107 -1.356 281.457 1.00 42.17 ? 140 ASN A O 1 ATOM 971 C CB . ASN A 1 140 ? -105.522 0.890 283.550 1.00 30.53 ? 140 ASN A CB 1 ATOM 972 C CG . ASN A 1 140 ? -106.000 1.539 284.833 1.00 27.00 ? 140 ASN A CG 1 ATOM 973 O OD1 . ASN A 1 140 ? -106.794 2.479 284.808 1.00 19.21 ? 140 ASN A OD1 1 ATOM 974 N ND2 . ASN A 1 140 ? -105.514 1.042 285.965 1.00 22.42 ? 140 ASN A ND2 1 ATOM 975 N N . LYS A 1 141 ? -106.837 -0.169 280.637 1.00 26.55 ? 141 LYS A N 1 ATOM 976 C CA . LYS A 1 141 ? -106.528 -0.464 279.246 1.00 33.09 ? 141 LYS A CA 1 ATOM 977 C C . LYS A 1 141 ? -106.936 0.727 278.394 1.00 38.59 ? 141 LYS A C 1 ATOM 978 O O . LYS A 1 141 ? -107.880 1.443 278.749 1.00 43.84 ? 141 LYS A O 1 ATOM 979 C CB . LYS A 1 141 ? -107.241 -1.737 278.759 1.00 32.63 ? 141 LYS A CB 1 ATOM 980 C CG . LYS A 1 141 ? -108.592 -1.999 279.397 1.00 31.87 ? 141 LYS A CG 1 ATOM 981 C CD . LYS A 1 141 ? -109.236 -3.249 278.811 1.00 36.07 ? 141 LYS A CD 1 ATOM 982 C CE . LYS A 1 141 ? -110.456 -3.682 279.610 1.00 39.16 ? 141 LYS A CE 1 ATOM 983 N NZ . LYS A 1 141 ? -111.532 -2.653 279.593 1.00 35.01 ? 141 LYS A NZ 1 ATOM 984 N N . PRO A 1 142 ? -106.239 0.976 277.272 1.00 35.65 ? 142 PRO A N 1 ATOM 985 C CA . PRO A 1 142 ? -106.538 2.067 276.332 1.00 38.42 ? 142 PRO A CA 1 ATOM 986 C C . PRO A 1 142 ? -107.973 2.019 275.805 1.00 46.67 ? 142 PRO A C 1 ATOM 987 O O . PRO A 1 142 ? -108.556 0.936 275.758 1.00 88.38 ? 142 PRO A O 1 ATOM 988 C CB . PRO A 1 142 ? -105.534 1.834 275.195 1.00 52.94 ? 142 PRO A CB 1 ATOM 989 C CG . PRO A 1 142 ? -104.431 1.061 275.809 1.00 38.58 ? 142 PRO A CG 1 ATOM 990 C CD . PRO A 1 142 ? -105.059 0.198 276.853 1.00 32.54 ? 142 PRO A CD 1 ATOM 991 N N . GLY A 1 143 ? -108.533 3.162 275.410 1.00 47.73 ? 143 GLY A N 1 ATOM 992 C CA . GLY A 1 143 ? -107.827 4.432 275.423 1.00 43.03 ? 143 GLY A CA 1 ATOM 993 C C . GLY A 1 143 ? -108.502 5.522 276.233 1.00 50.27 ? 143 GLY A C 1 ATOM 994 O O . GLY A 1 143 ? -108.967 5.283 277.347 1.00 67.70 ? 143 GLY A O 1 ATOM 995 N N . ARG A 1 144 ? -108.562 6.725 275.665 1.00 37.52 ? 144 ARG A N 1 ATOM 996 C CA . ARG A 1 144 ? -109.048 7.902 276.369 1.00 34.95 ? 144 ARG A CA 1 ATOM 997 C C . ARG A 1 144 ? -110.181 8.554 275.588 1.00 36.82 ? 144 ARG A C 1 ATOM 998 O O . ARG A 1 144 ? -110.189 8.554 274.354 1.00 51.75 ? 144 ARG A O 1 ATOM 999 C CB . ARG A 1 144 ? -107.916 8.919 276.591 1.00 32.96 ? 144 ARG A CB 1 ATOM 1000 C CG . ARG A 1 144 ? -108.291 10.105 277.465 1.00 36.53 ? 144 ARG A CG 1 ATOM 1001 C CD . ARG A 1 144 ? -107.163 11.126 277.542 1.00 36.17 ? 144 ARG A CD 1 ATOM 1002 N NE . ARG A 1 144 ? -106.971 11.839 276.282 1.00 27.06 ? 144 ARG A NE 1 ATOM 1003 C CZ . ARG A 1 144 ? -106.032 11.543 275.389 1.00 24.43 ? 144 ARG A CZ 1 ATOM 1004 N NH1 . ARG A 1 144 ? -105.188 10.546 275.616 1.00 23.92 ? 144 ARG A NH1 1 ATOM 1005 N NH2 . ARG A 1 144 ? -105.933 12.247 274.270 1.00 24.72 ? 144 ARG A NH2 1 ATOM 1006 N N . ARG A 1 145 ? -111.142 9.108 276.326 1.00 37.31 ? 145 ARG A N 1 ATOM 1007 C CA . ARG A 1 145 ? -112.231 9.882 275.740 1.00 40.46 ? 145 ARG A CA 1 ATOM 1008 C C . ARG A 1 145 ? -111.706 11.277 275.418 1.00 39.44 ? 145 ARG A C 1 ATOM 1009 O O . ARG A 1 145 ? -111.491 12.090 276.322 1.00 37.92 ? 145 ARG A O 1 ATOM 1010 C CB . ARG A 1 145 ? -113.414 9.942 276.702 1.00 45.97 ? 145 ARG A CB 1 ATOM 1011 C CG . ARG A 1 145 ? -114.618 10.708 276.182 1.00 78.63 ? 145 ARG A CG 1 ATOM 1012 C CD . ARG A 1 145 ? -115.335 9.936 275.088 1.00 70.73 ? 145 ARG A CD 1 ATOM 1013 N NE . ARG A 1 145 ? -116.489 10.668 274.572 1.00 72.75 ? 145 ARG A NE 1 ATOM 1014 C CZ . ARG A 1 145 ? -117.732 10.510 275.015 1.00 67.00 ? 145 ARG A CZ 1 ATOM 1015 N NH1 . ARG A 1 145 ? -117.986 9.643 275.986 1.00 70.86 ? 145 ARG A NH1 1 ATOM 1016 N NH2 . ARG A 1 145 ? -118.721 11.218 274.488 1.00 57.39 ? 145 ARG A NH2 1 ATOM 1017 N N . GLU A 1 146 ? -111.502 11.559 274.131 1.00 38.24 ? 146 GLU A N 1 ATOM 1018 C CA . GLU A 1 146 ? -110.786 12.763 273.726 1.00 36.43 ? 146 GLU A CA 1 ATOM 1019 C C . GLU A 1 146 ? -111.689 13.973 273.529 1.00 41.00 ? 146 GLU A C 1 ATOM 1020 O O . GLU A 1 146 ? -111.233 15.107 273.714 1.00 47.61 ? 146 GLU A O 1 ATOM 1021 C CB . GLU A 1 146 ? -110.002 12.496 272.438 1.00 37.70 ? 146 GLU A CB 1 ATOM 1022 C CG . GLU A 1 146 ? -108.887 11.477 272.606 1.00 38.00 ? 146 GLU A CG 1 ATOM 1023 C CD . GLU A 1 146 ? -107.894 11.502 271.464 1.00 36.45 ? 146 GLU A CD 1 ATOM 1024 O OE1 . GLU A 1 146 ? -108.111 12.267 270.502 1.00 35.87 ? 146 GLU A OE1 1 ATOM 1025 O OE2 . GLU A 1 146 ? -106.895 10.754 271.529 1.00 61.01 ? 146 GLU A OE2 1 ATOM 1026 N N . ASP A 1 147 ? -112.951 13.772 273.156 1.00 45.12 ? 147 ASP A N 1 ATOM 1027 C CA . ASP A 1 147 ? -113.858 14.896 272.964 1.00 43.48 ? 147 ASP A CA 1 ATOM 1028 C C . ASP A 1 147 ? -114.481 15.383 274.265 1.00 39.51 ? 147 ASP A C 1 ATOM 1029 O O . ASP A 1 147 ? -115.196 16.391 274.250 1.00 51.75 ? 147 ASP A O 1 ATOM 1030 C CB . ASP A 1 147 ? -114.964 14.526 271.972 1.00 46.04 ? 147 ASP A CB 1 ATOM 1031 C CG . ASP A 1 147 ? -115.784 13.339 272.432 1.00 58.62 ? 147 ASP A CG 1 ATOM 1032 O OD1 . ASP A 1 147 ? -115.212 12.439 273.080 1.00 66.25 ? 147 ASP A OD1 1 ATOM 1033 O OD2 . ASP A 1 147 ? -116.998 13.307 272.144 1.00 74.17 ? 147 ASP A OD2 1 ATOM 1034 N N . LYS A 1 148 ? -114.232 14.701 275.380 1.00 40.35 ? 148 LYS A N 1 ATOM 1035 C CA . LYS A 1 148 ? -114.759 15.095 276.677 1.00 36.74 ? 148 LYS A CA 1 ATOM 1036 C C . LYS A 1 148 ? -113.627 15.127 277.695 1.00 31.22 ? 148 LYS A C 1 ATOM 1037 O O . LYS A 1 148 ? -112.604 14.454 277.541 1.00 31.46 ? 148 LYS A O 1 ATOM 1038 C CB . LYS A 1 148 ? -115.869 14.144 277.149 1.00 41.35 ? 148 LYS A CB 1 ATOM 1039 C CG . LYS A 1 148 ? -117.049 14.046 276.193 1.00 45.92 ? 148 LYS A CG 1 ATOM 1040 C CD . LYS A 1 148 ? -117.830 15.350 276.140 1.00 50.29 ? 148 LYS A CD 1 ATOM 1041 C CE . LYS A 1 148 ? -119.067 15.218 275.267 1.00 43.68 ? 148 LYS A CE 1 ATOM 1042 N NZ . LYS A 1 148 ? -119.811 16.504 275.163 1.00 40.67 ? 148 LYS A NZ 1 ATOM 1043 N N . ILE A 1 149 ? -113.823 15.919 278.744 1.00 30.00 ? 149 ILE A N 1 ATOM 1044 C CA . ILE A 1 149 ? -112.803 16.104 279.770 1.00 26.79 ? 149 ILE A CA 1 ATOM 1045 C C . ILE A 1 149 ? -112.801 14.894 280.695 1.00 23.42 ? 149 ILE A C 1 ATOM 1046 O O . ILE A 1 149 ? -113.822 14.562 281.305 1.00 22.26 ? 149 ILE A O 1 ATOM 1047 C CB . ILE A 1 149 ? -113.039 17.400 280.559 1.00 26.40 ? 149 ILE A CB 1 ATOM 1048 C CG1 . ILE A 1 149 ? -112.989 18.609 279.624 1.00 29.08 ? 149 ILE A CG1 1 ATOM 1049 C CG2 . ILE A 1 149 ? -112.015 17.539 281.674 1.00 26.30 ? 149 ILE A CG2 1 ATOM 1050 C CD1 . ILE A 1 149 ? -111.669 18.773 278.907 1.00 31.62 ? 149 ILE A CD1 1 ATOM 1051 N N . VAL A 1 150 ? -111.651 14.234 280.802 1.00 22.43 ? 150 VAL A N 1 ATOM 1052 C CA . VAL A 1 150 ? -111.461 13.104 281.705 1.00 23.03 ? 150 VAL A CA 1 ATOM 1053 C C . VAL A 1 150 ? -110.357 13.504 282.676 1.00 24.09 ? 150 VAL A C 1 ATOM 1054 O O . VAL A 1 150 ? -109.167 13.390 282.360 1.00 23.55 ? 150 VAL A O 1 ATOM 1055 C CB . VAL A 1 150 ? -111.109 11.813 280.960 1.00 25.73 ? 150 VAL A CB 1 ATOM 1056 C CG1 . VAL A 1 150 ? -111.018 10.648 281.934 1.00 23.63 ? 150 VAL A CG1 1 ATOM 1057 C CG2 . VAL A 1 150 ? -112.137 11.529 279.876 1.00 28.93 ? 150 VAL A CG2 1 ATOM 1058 N N . ALA A 1 151 ? -110.744 13.975 283.855 1.00 24.23 ? 151 ALA A N 1 ATOM 1059 C CA . ALA A 1 151 ? -109.808 14.439 284.866 1.00 21.42 ? 151 ALA A CA 1 ATOM 1060 C C . ALA A 1 151 ? -109.770 13.470 286.039 1.00 19.12 ? 151 ALA A C 1 ATOM 1061 O O . ALA A 1 151 ? -110.638 12.607 286.199 1.00 21.20 ? 151 ALA A O 1 ATOM 1062 C CB . ALA A 1 151 ? -110.181 15.845 285.350 1.00 23.23 ? 151 ALA A CB 1 ATOM 1063 N N . ALA A 1 152 ? -108.740 13.625 286.866 1.00 15.94 ? 152 ALA A N 1 ATOM 1064 C CA . ALA A 1 152 ? -108.575 12.802 288.054 1.00 16.22 ? 152 ALA A CA 1 ATOM 1065 C C . ALA A 1 152 ? -107.690 13.547 289.039 1.00 18.58 ? 152 ALA A C 1 ATOM 1066 O O . ALA A 1 152 ? -106.862 14.374 288.648 1.00 22.07 ? 152 ALA A O 1 ATOM 1067 C CB . ALA A 1 152 ? -107.972 11.434 287.718 1.00 14.91 ? 152 ALA A CB 1 ATOM 1068 N N . TYR A 1 153 ? -107.877 13.246 290.319 1.00 15.31 ? 153 TYR A N 1 ATOM 1069 C CA . TYR A 1 153 ? -107.130 13.886 291.392 1.00 15.35 ? 153 TYR A CA 1 ATOM 1070 C C . TYR A 1 153 ? -106.028 12.960 291.885 1.00 18.95 ? 153 TYR A C 1 ATOM 1071 O O . TYR A 1 153 ? -106.289 11.803 292.231 1.00 22.02 ? 153 TYR A O 1 ATOM 1072 C CB . TYR A 1 153 ? -108.051 14.258 292.552 1.00 16.75 ? 153 TYR A CB 1 ATOM 1073 C CG . TYR A 1 153 ? -108.665 15.634 292.454 1.00 21.67 ? 153 TYR A CG 1 ATOM 1074 C CD1 . TYR A 1 153 ? -107.978 16.753 292.904 1.00 23.47 ? 153 TYR A CD1 1 ATOM 1075 C CD2 . TYR A 1 153 ? -109.939 15.814 291.932 1.00 37.06 ? 153 TYR A CD2 1 ATOM 1076 C CE1 . TYR A 1 153 ? -108.535 18.014 292.824 1.00 24.87 ? 153 TYR A CE1 1 ATOM 1077 C CE2 . TYR A 1 153 ? -110.507 17.072 291.851 1.00 23.51 ? 153 TYR A CE2 1 ATOM 1078 C CZ . TYR A 1 153 ? -109.799 18.168 292.296 1.00 25.77 ? 153 TYR A CZ 1 ATOM 1079 O OH . TYR A 1 153 ? -110.356 19.423 292.217 1.00 34.03 ? 153 TYR A OH 1 ATOM 1080 N N . PHE A 1 154 ? -104.803 13.476 291.924 1.00 17.60 ? 154 PHE A N 1 ATOM 1081 C CA . PHE A 1 154 ? -103.662 12.765 292.485 1.00 14.07 ? 154 PHE A CA 1 ATOM 1082 C C . PHE A 1 154 ? -103.345 13.358 293.851 1.00 12.85 ? 154 PHE A C 1 ATOM 1083 O O . PHE A 1 154 ? -103.108 14.565 293.967 1.00 13.44 ? 154 PHE A O 1 ATOM 1084 C CB . PHE A 1 154 ? -102.452 12.857 291.556 1.00 15.60 ? 154 PHE A CB 1 ATOM 1085 C CG . PHE A 1 154 ? -101.224 12.176 292.091 1.00 16.20 ? 154 PHE A CG 1 ATOM 1086 C CD1 . PHE A 1 154 ? -101.059 10.809 291.953 1.00 16.23 ? 154 PHE A CD1 1 ATOM 1087 C CD2 . PHE A 1 154 ? -100.228 12.905 292.721 1.00 14.86 ? 154 PHE A CD2 1 ATOM 1088 C CE1 . PHE A 1 154 ? -99.929 10.180 292.438 1.00 16.48 ? 154 PHE A CE1 1 ATOM 1089 C CE2 . PHE A 1 154 ? -99.097 12.282 293.209 1.00 14.20 ? 154 PHE A CE2 1 ATOM 1090 C CZ . PHE A 1 154 ? -98.947 10.917 293.067 1.00 17.49 ? 154 PHE A CZ 1 ATOM 1091 N N . VAL A 1 155 ? -103.345 12.517 294.876 1.00 13.80 ? 155 VAL A N 1 ATOM 1092 C CA . VAL A 1 155 ? -103.094 12.977 296.236 1.00 17.56 ? 155 VAL A CA 1 ATOM 1093 C C . VAL A 1 155 ? -101.593 13.080 296.467 1.00 18.72 ? 155 VAL A C 1 ATOM 1094 O O . VAL A 1 155 ? -100.815 12.228 296.018 1.00 20.14 ? 155 VAL A O 1 ATOM 1095 C CB . VAL A 1 155 ? -103.760 12.037 297.256 1.00 20.40 ? 155 VAL A CB 1 ATOM 1096 C CG1 . VAL A 1 155 ? -105.269 12.206 297.219 1.00 24.68 ? 155 VAL A CG1 1 ATOM 1097 C CG2 . VAL A 1 155 ? -103.379 10.595 296.977 1.00 24.54 ? 155 VAL A CG2 1 ATOM 1098 N N . GLU A 1 156 ? -101.180 14.137 297.168 1.00 18.18 ? 156 GLU A N 1 ATOM 1099 C CA . GLU A 1 156 ? -99.762 14.327 297.456 1.00 16.83 ? 156 GLU A CA 1 ATOM 1100 C C . GLU A 1 156 ? -99.250 13.276 298.433 1.00 17.92 ? 156 GLU A C 1 ATOM 1101 O O . GLU A 1 156 ? -98.122 12.789 298.295 1.00 18.10 ? 156 GLU A O 1 ATOM 1102 C CB . GLU A 1 156 ? -99.528 15.734 298.006 1.00 15.50 ? 156 GLU A CB 1 ATOM 1103 C CG . GLU A 1 156 ? -98.111 15.996 298.485 1.00 16.55 ? 156 GLU A CG 1 ATOM 1104 C CD . GLU A 1 156 ? -97.865 17.460 298.791 1.00 18.90 ? 156 GLU A CD 1 ATOM 1105 O OE1 . GLU A 1 156 ? -97.904 17.836 299.981 1.00 19.55 ? 156 GLU A OE1 1 ATOM 1106 O OE2 . GLU A 1 156 ? -97.634 18.236 297.840 1.00 16.80 ? 156 GLU A OE2 1 ATOM 1107 N N . TRP A 1 157 ? -100.065 12.909 299.418 1.00 19.54 ? 157 TRP A N 1 ATOM 1108 C CA . TRP A 1 157 ? -99.687 11.932 300.430 1.00 18.98 ? 157 TRP A CA 1 ATOM 1109 C C . TRP A 1 157 ? -99.888 10.492 299.973 1.00 20.07 ? 157 TRP A C 1 ATOM 1110 O O . TRP A 1 157 ? -99.851 9.584 300.809 1.00 19.78 ? 157 TRP A O 1 ATOM 1111 C CB . TRP A 1 157 ? -100.477 12.182 301.718 1.00 21.97 ? 157 TRP A CB 1 ATOM 1112 C CG . TRP A 1 157 ? -101.964 12.093 301.537 1.00 26.97 ? 157 TRP A CG 1 ATOM 1113 C CD1 . TRP A 1 157 ? -102.761 11.022 301.818 1.00 42.08 ? 157 TRP A CD1 1 ATOM 1114 C CD2 . TRP A 1 157 ? -102.832 13.117 301.033 1.00 25.68 ? 157 TRP A CD2 1 ATOM 1115 N NE1 . TRP A 1 157 ? -104.070 11.315 301.522 1.00 41.00 ? 157 TRP A NE1 1 ATOM 1116 C CE2 . TRP A 1 157 ? -104.141 12.595 301.038 1.00 27.81 ? 157 TRP A CE2 1 ATOM 1117 C CE3 . TRP A 1 157 ? -102.630 14.424 300.579 1.00 22.79 ? 157 TRP A CE3 1 ATOM 1118 C CZ2 . TRP A 1 157 ? -105.240 13.333 300.607 1.00 29.03 ? 157 TRP A CZ2 1 ATOM 1119 C CZ3 . TRP A 1 157 ? -103.724 15.154 300.151 1.00 20.98 ? 157 TRP A CZ3 1 ATOM 1120 C CH2 . TRP A 1 157 ? -105.012 14.607 300.168 1.00 23.91 ? 157 TRP A CH2 1 ATOM 1121 N N . GLY A 1 158 ? -100.097 10.262 298.677 1.00 18.54 ? 158 GLY A N 1 ATOM 1122 C CA . GLY A 1 158 ? -100.333 8.921 298.178 1.00 16.40 ? 158 GLY A CA 1 ATOM 1123 C C . GLY A 1 158 ? -99.105 8.048 298.054 1.00 17.63 ? 158 GLY A C 1 ATOM 1124 O O . GLY A 1 158 ? -99.240 6.850 297.788 1.00 16.63 ? 158 GLY A O 1 ATOM 1125 N N . VAL A 1 159 ? -97.909 8.614 298.240 1.00 19.64 ? 159 VAL A N 1 ATOM 1126 C CA . VAL A 1 159 ? -96.681 7.829 298.126 1.00 20.41 ? 159 VAL A CA 1 ATOM 1127 C C . VAL A 1 159 ? -96.347 7.062 299.392 1.00 23.12 ? 159 VAL A C 1 ATOM 1128 O O . VAL A 1 159 ? -95.436 6.226 299.374 1.00 23.70 ? 159 VAL A O 1 ATOM 1129 C CB . VAL A 1 159 ? -95.482 8.726 297.766 1.00 23.54 ? 159 VAL A CB 1 ATOM 1130 C CG1 . VAL A 1 159 ? -95.707 9.402 296.423 1.00 24.73 ? 159 VAL A CG1 1 ATOM 1131 C CG2 . VAL A 1 159 ? -95.249 9.752 298.859 1.00 22.19 ? 159 VAL A CG2 1 ATOM 1132 N N . TYR A 1 160 ? -97.054 7.318 300.492 1.00 22.13 ? 160 TYR A N 1 ATOM 1133 C CA . TYR A 1 160 ? -96.772 6.639 301.750 1.00 18.49 ? 160 TYR A CA 1 ATOM 1134 C C . TYR A 1 160 ? -97.538 5.326 301.852 1.00 20.04 ? 160 TYR A C 1 ATOM 1135 O O . TYR A 1 160 ? -97.220 4.360 301.151 1.00 23.16 ? 160 TYR A O 1 ATOM 1136 C CB . TYR A 1 160 ? -97.111 7.545 302.934 1.00 17.90 ? 160 TYR A CB 1 ATOM 1137 C CG . TYR A 1 160 ? -96.284 8.808 302.990 1.00 21.15 ? 160 TYR A CG 1 ATOM 1138 C CD1 . TYR A 1 160 ? -94.917 8.754 303.224 1.00 19.76 ? 160 TYR A CD1 1 ATOM 1139 C CD2 . TYR A 1 160 ? -96.868 10.054 302.811 1.00 25.95 ? 160 TYR A CD2 1 ATOM 1140 C CE1 . TYR A 1 160 ? -94.155 9.904 303.277 1.00 20.12 ? 160 TYR A CE1 1 ATOM 1141 C CE2 . TYR A 1 160 ? -96.114 11.211 302.862 1.00 25.13 ? 160 TYR A CE2 1 ATOM 1142 C CZ . TYR A 1 160 ? -94.758 11.129 303.096 1.00 23.63 ? 160 TYR A CZ 1 ATOM 1143 O OH . TYR A 1 160 ? -94.001 12.276 303.148 1.00 35.98 ? 160 TYR A OH 1 ATOM 1144 N N . GLY A 1 161 ? -98.546 5.285 302.726 1.00 15.98 ? 161 GLY A N 1 ATOM 1145 C CA . GLY A 1 161 ? -99.288 4.050 302.929 1.00 15.49 ? 161 GLY A CA 1 ATOM 1146 C C . GLY A 1 161 ? -99.997 3.575 301.676 1.00 19.74 ? 161 GLY A C 1 ATOM 1147 O O . GLY A 1 161 ? -100.081 2.372 301.417 1.00 24.77 ? 161 GLY A O 1 ATOM 1148 N N . ARG A 1 162 ? -100.515 4.512 300.878 1.00 19.29 ? 162 ARG A N 1 ATOM 1149 C CA . ARG A 1 162 ? -101.198 4.131 299.646 1.00 17.89 ? 162 ARG A CA 1 ATOM 1150 C C . ARG A 1 162 ? -100.231 3.558 298.619 1.00 17.72 ? 162 ARG A C 1 ATOM 1151 O O . ARG A 1 162 ? -100.625 2.707 297.812 1.00 18.45 ? 162 ARG A O 1 ATOM 1152 C CB . ARG A 1 162 ? -101.944 5.333 299.067 1.00 23.16 ? 162 ARG A CB 1 ATOM 1153 C CG . ARG A 1 162 ? -103.194 5.713 299.842 1.00 21.18 ? 162 ARG A CG 1 ATOM 1154 C CD . ARG A 1 162 ? -103.846 6.961 299.271 1.00 17.40 ? 162 ARG A CD 1 ATOM 1155 N NE . ARG A 1 162 ? -105.186 7.175 299.810 1.00 22.29 ? 162 ARG A NE 1 ATOM 1156 C CZ . ARG A 1 162 ? -105.439 7.706 301.002 1.00 24.22 ? 162 ARG A CZ 1 ATOM 1157 N NH1 . ARG A 1 162 ? -104.442 8.080 301.792 1.00 24.91 ? 162 ARG A NH1 1 ATOM 1158 N NH2 . ARG A 1 162 ? -106.693 7.862 301.406 1.00 24.03 ? 162 ARG A NH2 1 ATOM 1159 N N . ASN A 1 163 ? -98.975 4.002 298.635 1.00 18.45 ? 163 ASN A N 1 ATOM 1160 C CA . ASN A 1 163 ? -97.934 3.514 297.731 1.00 21.05 ? 163 ASN A CA 1 ATOM 1161 C C . ASN A 1 163 ? -98.375 3.637 296.272 1.00 17.75 ? 163 ASN A C 1 ATOM 1162 O O . ASN A 1 163 ? -98.462 2.658 295.529 1.00 17.35 ? 163 ASN A O 1 ATOM 1163 C CB . ASN A 1 163 ? -97.548 2.072 298.072 1.00 28.86 ? 163 ASN A CB 1 ATOM 1164 C CG . ASN A 1 163 ? -96.272 1.631 297.383 1.00 29.30 ? 163 ASN A CG 1 ATOM 1165 O OD1 . ASN A 1 163 ? -95.343 2.419 297.206 1.00 23.58 ? 163 ASN A OD1 1 ATOM 1166 N ND2 . ASN A 1 163 ? -96.221 0.364 296.986 1.00 50.25 ? 163 ASN A ND2 1 ATOM 1167 N N . PHE A 1 164 ? -98.656 4.873 295.871 1.00 16.68 ? 164 PHE A N 1 ATOM 1168 C CA . PHE A 1 164 ? -99.153 5.172 294.528 1.00 15.15 ? 164 PHE A CA 1 ATOM 1169 C C . PHE A 1 164 ? -98.459 6.418 294.002 1.00 15.69 ? 164 PHE A C 1 ATOM 1170 O O . PHE A 1 164 ? -99.016 7.522 294.031 1.00 13.71 ? 164 PHE A O 1 ATOM 1171 C CB . PHE A 1 164 ? -100.673 5.349 294.535 1.00 16.88 ? 164 PHE A CB 1 ATOM 1172 C CG . PHE A 1 164 ? -101.317 5.132 293.197 1.00 16.40 ? 164 PHE A CG 1 ATOM 1173 C CD1 . PHE A 1 164 ? -101.379 6.156 292.268 1.00 18.22 ? 164 PHE A CD1 1 ATOM 1174 C CD2 . PHE A 1 164 ? -101.871 3.906 292.873 1.00 15.99 ? 164 PHE A CD2 1 ATOM 1175 C CE1 . PHE A 1 164 ? -101.975 5.959 291.038 1.00 15.60 ? 164 PHE A CE1 1 ATOM 1176 C CE2 . PHE A 1 164 ? -102.469 3.703 291.644 1.00 15.52 ? 164 PHE A CE2 1 ATOM 1177 C CZ . PHE A 1 164 ? -102.521 4.731 290.727 1.00 15.39 ? 164 PHE A CZ 1 ATOM 1178 N N . PRO A 1 165 ? -97.233 6.281 293.513 1.00 17.69 ? 165 PRO A N 1 ATOM 1179 C CA . PRO A 1 165 ? -96.528 7.418 292.915 1.00 21.73 ? 165 PRO A CA 1 ATOM 1180 C C . PRO A 1 165 ? -97.065 7.711 291.517 1.00 20.76 ? 165 PRO A C 1 ATOM 1181 O O . PRO A 1 165 ? -97.977 7.052 291.022 1.00 18.64 ? 165 PRO A O 1 ATOM 1182 C CB . PRO A 1 165 ? -95.073 6.945 292.878 1.00 17.10 ? 165 PRO A CB 1 ATOM 1183 C CG . PRO A 1 165 ? -95.172 5.466 292.781 1.00 14.22 ? 165 PRO A CG 1 ATOM 1184 C CD . PRO A 1 165 ? -96.389 5.075 293.569 1.00 17.33 ? 165 PRO A CD 1 ATOM 1185 N N . VAL A 1 166 ? -96.467 8.722 290.880 1.00 13.62 ? 166 VAL A N 1 ATOM 1186 C CA . VAL A 1 166 ? -96.947 9.180 289.579 1.00 13.49 ? 166 VAL A CA 1 ATOM 1187 C C . VAL A 1 166 ? -96.807 8.091 288.525 1.00 16.08 ? 166 VAL A C 1 ATOM 1188 O O . VAL A 1 166 ? -97.644 7.979 287.620 1.00 16.07 ? 166 VAL A O 1 ATOM 1189 C CB . VAL A 1 166 ? -96.203 10.463 289.163 1.00 14.27 ? 166 VAL A CB 1 ATOM 1190 C CG1 . VAL A 1 166 ? -96.724 10.974 287.830 1.00 11.54 ? 166 VAL A CG1 1 ATOM 1191 C CG2 . VAL A 1 166 ? -96.341 11.525 290.241 1.00 42.50 ? 166 VAL A CG2 1 ATOM 1192 N N . ASP A 1 167 ? -95.764 7.264 288.624 1.00 15.51 ? 167 ASP A N 1 ATOM 1193 C CA . ASP A 1 167 ? -95.553 6.202 287.646 1.00 14.45 ? 167 ASP A CA 1 ATOM 1194 C C . ASP A 1 167 ? -96.649 5.144 287.672 1.00 15.51 ? 167 ASP A C 1 ATOM 1195 O O . ASP A 1 167 ? -96.642 4.250 286.818 1.00 14.04 ? 167 ASP A O 1 ATOM 1196 C CB . ASP A 1 167 ? -94.189 5.550 287.873 1.00 12.85 ? 167 ASP A CB 1 ATOM 1197 C CG . ASP A 1 167 ? -94.013 5.047 289.289 1.00 14.07 ? 167 ASP A CG 1 ATOM 1198 O OD1 . ASP A 1 167 ? -94.453 3.916 289.579 1.00 35.89 ? 167 ASP A OD1 1 ATOM 1199 O OD2 . ASP A 1 167 ? -93.432 5.785 290.113 1.00 13.96 ? 167 ASP A OD2 1 ATOM 1200 N N . LYS A 1 168 ? -97.583 5.219 288.620 1.00 13.85 ? 168 LYS A N 1 ATOM 1201 C CA . LYS A 1 168 ? -98.736 4.331 288.657 1.00 15.48 ? 168 LYS A CA 1 ATOM 1202 C C . LYS A 1 168 ? -100.013 4.990 288.156 1.00 15.94 ? 168 LYS A C 1 ATOM 1203 O O . LYS A 1 168 ? -101.038 4.310 288.042 1.00 14.77 ? 168 LYS A O 1 ATOM 1204 C CB . LYS A 1 168 ? -98.967 3.818 290.083 1.00 14.34 ? 168 LYS A CB 1 ATOM 1205 C CG . LYS A 1 168 ? -97.890 2.888 290.609 1.00 12.82 ? 168 LYS A CG 1 ATOM 1206 C CD . LYS A 1 168 ? -98.280 2.344 291.973 1.00 14.75 ? 168 LYS A CD 1 ATOM 1207 C CE . LYS A 1 168 ? -97.314 1.276 292.449 1.00 20.51 ? 168 LYS A CE 1 ATOM 1208 N NZ . LYS A 1 168 ? -97.745 0.691 293.749 1.00 44.32 ? 168 LYS A NZ 1 ATOM 1209 N N . VAL A 1 169 ? -99.980 6.281 287.854 1.00 15.54 ? 169 VAL A N 1 ATOM 1210 C CA . VAL A 1 169 ? -101.199 7.011 287.501 1.00 15.86 ? 169 VAL A CA 1 ATOM 1211 C C . VAL A 1 169 ? -101.533 6.735 286.037 1.00 20.17 ? 169 VAL A C 1 ATOM 1212 O O . VAL A 1 169 ? -100.664 6.907 285.169 1.00 21.15 ? 169 VAL A O 1 ATOM 1213 C CB . VAL A 1 169 ? -101.020 8.504 287.751 1.00 14.49 ? 169 VAL A CB 1 ATOM 1214 C CG1 . VAL A 1 169 ? -102.292 9.256 287.396 1.00 15.43 ? 169 VAL A CG1 1 ATOM 1215 C CG2 . VAL A 1 169 ? -100.631 8.752 289.196 1.00 13.73 ? 169 VAL A CG2 1 ATOM 1216 N N . PRO A 1 170 ? -102.764 6.322 285.724 1.00 19.69 ? 170 PRO A N 1 ATOM 1217 C CA . PRO A 1 170 ? -103.116 6.033 284.327 1.00 18.39 ? 170 PRO A CA 1 ATOM 1218 C C . PRO A 1 170 ? -103.254 7.296 283.491 1.00 19.82 ? 170 PRO A C 1 ATOM 1219 O O . PRO A 1 170 ? -104.358 7.663 283.079 1.00 19.87 ? 170 PRO A O 1 ATOM 1220 C CB . PRO A 1 170 ? -104.456 5.291 284.442 1.00 22.79 ? 170 PRO A CB 1 ATOM 1221 C CG . PRO A 1 170 ? -104.633 4.985 285.911 1.00 22.64 ? 170 PRO A CG 1 ATOM 1222 C CD . PRO A 1 170 ? -103.877 6.038 286.642 1.00 16.17 ? 170 PRO A CD 1 ATOM 1223 N N . LEU A 1 171 ? -102.129 7.959 283.234 1.00 20.71 ? 171 LEU A N 1 ATOM 1224 C CA . LEU A 1 171 ? -102.161 9.213 282.485 1.00 20.47 ? 171 LEU A CA 1 ATOM 1225 C C . LEU A 1 171 ? -102.634 9.073 281.041 1.00 23.58 ? 171 LEU A C 1 ATOM 1226 O O . LEU A 1 171 ? -103.306 10.002 280.559 1.00 30.05 ? 171 LEU A O 1 ATOM 1227 C CB . LEU A 1 171 ? -100.777 9.869 282.541 1.00 18.54 ? 171 LEU A CB 1 ATOM 1228 C CG . LEU A 1 171 ? -100.319 10.212 283.958 1.00 21.66 ? 171 LEU A CG 1 ATOM 1229 C CD1 . LEU A 1 171 ? -98.904 10.745 283.945 1.00 18.26 ? 171 LEU A CD1 1 ATOM 1230 C CD2 . LEU A 1 171 ? -101.267 11.219 284.586 1.00 17.19 ? 171 LEU A CD2 1 ATOM 1231 N N . PRO A 1 172 ? -102.323 8.003 280.296 1.00 22.98 ? 172 PRO A N 1 ATOM 1232 C CA . PRO A 1 172 ? -102.859 7.899 278.926 1.00 24.09 ? 172 PRO A CA 1 ATOM 1233 C C . PRO A 1 172 ? -104.375 7.979 278.842 1.00 25.19 ? 172 PRO A C 1 ATOM 1234 O O . PRO A 1 172 ? -104.899 8.349 277.785 1.00 34.80 ? 172 PRO A O 1 ATOM 1235 C CB . PRO A 1 172 ? -102.344 6.534 278.454 1.00 23.44 ? 172 PRO A CB 1 ATOM 1236 C CG . PRO A 1 172 ? -101.086 6.346 279.202 1.00 23.43 ? 172 PRO A CG 1 ATOM 1237 C CD . PRO A 1 172 ? -101.317 6.955 280.556 1.00 21.23 ? 172 PRO A CD 1 ATOM 1238 N N . ASN A 1 173 ? -105.096 7.650 279.913 1.00 23.34 ? 173 ASN A N 1 ATOM 1239 C CA . ASN A 1 173 ? -106.549 7.745 279.936 1.00 24.07 ? 173 ASN A CA 1 ATOM 1240 C C . ASN A 1 173 ? -107.039 9.007 280.636 1.00 23.02 ? 173 ASN A C 1 ATOM 1241 O O . ASN A 1 173 ? -108.195 9.059 281.069 1.00 25.65 ? 173 ASN A O 1 ATOM 1242 C CB . ASN A 1 173 ? -107.151 6.508 280.606 1.00 26.17 ? 173 ASN A CB 1 ATOM 1243 C CG . ASN A 1 173 ? -106.861 5.232 279.843 1.00 28.26 ? 173 ASN A CG 1 ATOM 1244 O OD1 . ASN A 1 173 ? -106.493 5.265 278.670 1.00 27.80 ? 173 ASN A OD1 1 ATOM 1245 N ND2 . ASN A 1 173 ? -107.033 4.095 280.508 1.00 26.10 ? 173 ASN A ND2 1 ATOM 1246 N N . LEU A 1 174 ? -106.188 10.024 280.755 1.00 20.19 ? 174 LEU A N 1 ATOM 1247 C CA . LEU A 1 174 ? -106.528 11.247 281.467 1.00 21.52 ? 174 LEU A CA 1 ATOM 1248 C C . LEU A 1 174 ? -106.150 12.463 280.636 1.00 26.26 ? 174 LEU A C 1 ATOM 1249 O O . LEU A 1 174 ? -105.072 12.507 280.036 1.00 32.34 ? 174 LEU A O 1 ATOM 1250 C CB . LEU A 1 174 ? -105.821 11.317 282.825 1.00 17.87 ? 174 LEU A CB 1 ATOM 1251 C CG . LEU A 1 174 ? -106.212 10.267 283.863 1.00 16.57 ? 174 LEU A CG 1 ATOM 1252 C CD1 . LEU A 1 174 ? -105.416 10.462 285.142 1.00 15.82 ? 174 LEU A CD1 1 ATOM 1253 C CD2 . LEU A 1 174 ? -107.702 10.330 284.143 1.00 16.10 ? 174 LEU A CD2 1 ATOM 1254 N N . SER A 1 175 ? -107.045 13.449 280.608 1.00 25.79 ? 175 SER A N 1 ATOM 1255 C CA . SER A 1 175 ? -106.761 14.740 279.997 1.00 24.99 ? 175 SER A CA 1 ATOM 1256 C C . SER A 1 175 ? -106.290 15.777 281.004 1.00 26.84 ? 175 SER A C 1 ATOM 1257 O O . SER A 1 175 ? -105.556 16.699 280.632 1.00 40.78 ? 175 SER A O 1 ATOM 1258 C CB . SER A 1 175 ? -108.001 15.271 279.271 1.00 25.95 ? 175 SER A CB 1 ATOM 1259 O OG . SER A 1 175 ? -109.052 15.528 280.185 1.00 41.71 ? 175 SER A OG 1 ATOM 1260 N N . HIS A 1 176 ? -106.696 15.649 282.265 1.00 22.83 ? 176 HIS A N 1 ATOM 1261 C CA . HIS A 1 176 ? -106.224 16.506 283.342 1.00 21.79 ? 176 HIS A CA 1 ATOM 1262 C C . HIS A 1 176 ? -105.746 15.650 284.503 1.00 20.13 ? 176 HIS A C 1 ATOM 1263 O O . HIS A 1 176 ? -106.360 14.630 284.829 1.00 19.16 ? 176 HIS A O 1 ATOM 1264 C CB . HIS A 1 176 ? -107.314 17.463 283.839 1.00 26.86 ? 176 HIS A CB 1 ATOM 1265 C CG . HIS A 1 176 ? -107.760 18.466 282.822 1.00 26.75 ? 176 HIS A CG 1 ATOM 1266 N ND1 . HIS A 1 176 ? -108.636 18.156 281.805 1.00 39.90 ? 176 HIS A ND1 1 ATOM 1267 C CD2 . HIS A 1 176 ? -107.459 19.777 282.674 1.00 23.61 ? 176 HIS A CD2 1 ATOM 1268 C CE1 . HIS A 1 176 ? -108.854 19.233 281.072 1.00 40.74 ? 176 HIS A CE1 1 ATOM 1269 N NE2 . HIS A 1 176 ? -108.151 20.230 281.577 1.00 30.01 ? 176 HIS A NE2 1 ATOM 1270 N N . LEU A 1 177 ? -104.648 16.073 285.122 1.00 20.21 ? 177 LEU A N 1 ATOM 1271 C CA . LEU A 1 177 ? -104.147 15.478 286.355 1.00 18.47 ? 177 LEU A CA 1 ATOM 1272 C C . LEU A 1 177 ? -104.127 16.581 287.404 1.00 19.35 ? 177 LEU A C 1 ATOM 1273 O O . LEU A 1 177 ? -103.343 17.530 287.299 1.00 25.53 ? 177 LEU A O 1 ATOM 1274 C CB . LEU A 1 177 ? -102.761 14.867 286.154 1.00 19.50 ? 177 LEU A CB 1 ATOM 1275 C CG . LEU A 1 177 ? -102.263 13.861 287.198 1.00 17.47 ? 177 LEU A CG 1 ATOM 1276 C CD1 . LEU A 1 177 ? -101.647 14.560 288.401 1.00 16.68 ? 177 LEU A CD1 1 ATOM 1277 C CD2 . LEU A 1 177 ? -103.392 12.938 287.633 1.00 20.53 ? 177 LEU A CD2 1 ATOM 1278 N N . LEU A 1 178 ? -104.993 16.464 288.404 1.00 19.24 ? 178 LEU A N 1 ATOM 1279 C CA . LEU A 1 178 ? -105.175 17.505 289.408 1.00 20.11 ? 178 LEU A CA 1 ATOM 1280 C C . LEU A 1 178 ? -104.353 17.143 290.639 1.00 17.86 ? 178 LEU A C 1 ATOM 1281 O O . LEU A 1 178 ? -104.628 16.143 291.308 1.00 20.46 ? 178 LEU A O 1 ATOM 1282 C CB . LEU A 1 178 ? -106.656 17.665 289.743 1.00 22.43 ? 178 LEU A CB 1 ATOM 1283 C CG . LEU A 1 178 ? -107.534 17.980 288.527 1.00 24.75 ? 178 LEU A CG 1 ATOM 1284 C CD1 . LEU A 1 178 ? -108.984 18.180 288.925 1.00 24.07 ? 178 LEU A CD1 1 ATOM 1285 C CD2 . LEU A 1 178 ? -107.012 19.204 287.790 1.00 23.47 ? 178 LEU A CD2 1 ATOM 1286 N N . TYR A 1 179 ? -103.350 17.965 290.937 1.00 17.75 ? 179 TYR A N 1 ATOM 1287 C CA . TYR A 1 179 ? -102.432 17.718 292.043 1.00 17.16 ? 179 TYR A CA 1 ATOM 1288 C C . TYR A 1 179 ? -102.981 18.380 293.301 1.00 14.22 ? 179 TYR A C 1 ATOM 1289 O O . TYR A 1 179 ? -102.983 19.610 293.414 1.00 15.40 ? 179 TYR A O 1 ATOM 1290 C CB . TYR A 1 179 ? -101.038 18.243 291.709 1.00 15.78 ? 179 TYR A CB 1 ATOM 1291 C CG . TYR A 1 179 ? -100.009 17.997 292.790 1.00 13.97 ? 179 TYR A CG 1 ATOM 1292 C CD1 . TYR A 1 179 ? -99.262 16.827 292.811 1.00 14.71 ? 179 TYR A CD1 1 ATOM 1293 C CD2 . TYR A 1 179 ? -99.777 18.939 293.783 1.00 14.16 ? 179 TYR A CD2 1 ATOM 1294 C CE1 . TYR A 1 179 ? -98.320 16.600 293.794 1.00 14.50 ? 179 TYR A CE1 1 ATOM 1295 C CE2 . TYR A 1 179 ? -98.839 18.720 294.770 1.00 17.83 ? 179 TYR A CE2 1 ATOM 1296 C CZ . TYR A 1 179 ? -98.113 17.550 294.770 1.00 14.17 ? 179 TYR A CZ 1 ATOM 1297 O OH . TYR A 1 179 ? -97.176 17.330 295.750 1.00 13.33 ? 179 TYR A OH 1 ATOM 1298 N N . GLY A 1 180 ? -103.439 17.567 294.245 1.00 15.01 ? 180 GLY A N 1 ATOM 1299 C CA . GLY A 1 180 ? -103.943 18.075 295.505 1.00 15.13 ? 180 GLY A CA 1 ATOM 1300 C C . GLY A 1 180 ? -103.104 17.641 296.691 1.00 15.90 ? 180 GLY A C 1 ATOM 1301 O O . GLY A 1 180 ? -102.762 16.465 296.813 1.00 17.55 ? 180 GLY A O 1 ATOM 1302 N N . PHE A 1 181 ? -102.770 18.584 297.567 1.00 16.96 ? 181 PHE A N 1 ATOM 1303 C CA . PHE A 1 181 ? -103.189 19.973 297.418 1.00 20.52 ? 181 PHE A CA 1 ATOM 1304 C C . PHE A 1 181 ? -102.026 20.936 297.630 1.00 22.62 ? 181 PHE A C 1 ATOM 1305 O O . PHE A 1 181 ? -101.057 20.614 298.317 1.00 21.24 ? 181 PHE A O 1 ATOM 1306 C CB . PHE A 1 181 ? -104.312 20.304 298.402 1.00 19.81 ? 181 PHE A CB 1 ATOM 1307 C CG . PHE A 1 181 ? -105.626 19.661 298.067 1.00 20.45 ? 181 PHE A CG 1 ATOM 1308 C CD1 . PHE A 1 181 ? -106.383 20.116 297.001 1.00 21.15 ? 181 PHE A CD1 1 ATOM 1309 C CD2 . PHE A 1 181 ? -106.109 18.607 298.823 1.00 20.97 ? 181 PHE A CD2 1 ATOM 1310 C CE1 . PHE A 1 181 ? -107.592 19.528 296.690 1.00 19.33 ? 181 PHE A CE1 1 ATOM 1311 C CE2 . PHE A 1 181 ? -107.318 18.015 298.518 1.00 24.59 ? 181 PHE A CE2 1 ATOM 1312 C CZ . PHE A 1 181 ? -108.060 18.477 297.450 1.00 22.89 ? 181 PHE A CZ 1 ATOM 1313 N N . ILE A 1 182 ? -102.132 22.119 297.036 1.00 22.47 ? 182 ILE A N 1 ATOM 1314 C CA . ILE A 1 182 ? -101.157 23.187 297.231 1.00 21.24 ? 182 ILE A CA 1 ATOM 1315 C C . ILE A 1 182 ? -101.651 24.062 298.380 1.00 22.06 ? 182 ILE A C 1 ATOM 1316 O O . ILE A 1 182 ? -102.706 24.701 298.243 1.00 23.57 ? 182 ILE A O 1 ATOM 1317 C CB . ILE A 1 182 ? -100.964 24.014 295.956 1.00 19.76 ? 182 ILE A CB 1 ATOM 1318 C CG1 . ILE A 1 182 ? -100.393 23.138 294.839 1.00 21.17 ? 182 ILE A CG1 1 ATOM 1319 C CG2 . ILE A 1 182 ? -100.055 25.202 296.228 1.00 22.23 ? 182 ILE A CG2 1 ATOM 1320 C CD1 . ILE A 1 182 ? -99.096 22.453 295.206 1.00 22.57 ? 182 ILE A CD1 1 ATOM 1321 N N . PRO A 1 183 ? -100.941 24.122 299.499 1.00 21.85 ? 183 PRO A N 1 ATOM 1322 C CA . PRO A 1 183 ? -101.459 24.826 300.674 1.00 22.83 ? 183 PRO A CA 1 ATOM 1323 C C . PRO A 1 183 ? -101.261 26.333 300.574 1.00 23.23 ? 183 PRO A C 1 ATOM 1324 O O . PRO A 1 183 ? -100.581 26.851 299.688 1.00 23.74 ? 183 PRO A O 1 ATOM 1325 C CB . PRO A 1 183 ? -100.627 24.241 301.816 1.00 24.17 ? 183 PRO A CB 1 ATOM 1326 C CG . PRO A 1 183 ? -99.321 23.929 301.174 1.00 23.80 ? 183 PRO A CG 1 ATOM 1327 C CD . PRO A 1 183 ? -99.643 23.481 299.769 1.00 22.64 ? 183 PRO A CD 1 ATOM 1328 N N . ILE A 1 184 ? -101.886 27.033 301.518 1.00 25.90 ? 184 ILE A N 1 ATOM 1329 C CA . ILE A 1 184 ? -101.697 28.464 301.715 1.00 27.13 ? 184 ILE A CA 1 ATOM 1330 C C . ILE A 1 184 ? -101.135 28.668 303.113 1.00 25.93 ? 184 ILE A C 1 ATOM 1331 O O . ILE A 1 184 ? -101.704 28.173 304.093 1.00 25.09 ? 184 ILE A O 1 ATOM 1332 C CB . ILE A 1 184 ? -103.008 29.249 301.533 1.00 24.45 ? 184 ILE A CB 1 ATOM 1333 C CG1 . ILE A 1 184 ? -103.609 28.958 300.161 1.00 25.13 ? 184 ILE A CG1 1 ATOM 1334 C CG2 . ILE A 1 184 ? -102.755 30.738 301.681 1.00 22.99 ? 184 ILE A CG2 1 ATOM 1335 C CD1 . ILE A 1 184 ? -102.689 29.324 299.033 1.00 24.80 ? 184 ILE A CD1 1 ATOM 1336 N N . CYS A 1 185 ? -100.022 29.390 303.202 1.00 26.51 ? 185 CYS A N 1 ATOM 1337 C CA . CYS A 1 185 ? -99.341 29.556 304.477 1.00 29.82 ? 185 CYS A CA 1 ATOM 1338 C C . CYS A 1 185 ? -100.219 30.316 305.466 1.00 30.47 ? 185 CYS A C 1 ATOM 1339 O O . CYS A 1 185 ? -101.029 31.167 305.091 1.00 32.08 ? 185 CYS A O 1 ATOM 1340 C CB . CYS A 1 185 ? -98.014 30.286 304.278 1.00 33.25 ? 185 CYS A CB 1 ATOM 1341 S SG . CYS A 1 185 ? -96.723 29.275 303.514 1.00 37.89 ? 185 CYS A SG 1 ATOM 1342 N N . GLY A 1 186 ? -100.051 29.991 306.744 1.00 29.73 ? 186 GLY A N 1 ATOM 1343 C CA . GLY A 1 186 ? -100.827 30.610 307.798 1.00 24.69 ? 186 GLY A CA 1 ATOM 1344 C C . GLY A 1 186 ? -100.738 29.844 309.101 1.00 25.62 ? 186 GLY A C 1 ATOM 1345 O O . GLY A 1 186 ? -100.639 28.613 309.097 1.00 25.16 ? 186 GLY A O 1 ATOM 1346 N N . GLY A 1 187 ? -100.768 30.556 310.217 1.00 27.41 ? 187 GLY A N 1 ATOM 1347 C CA . GLY A 1 187 ? -100.666 29.960 311.538 1.00 44.96 ? 187 GLY A CA 1 ATOM 1348 C C . GLY A 1 187 ? -102.019 29.767 312.186 1.00 27.45 ? 187 GLY A C 1 ATOM 1349 O O . GLY A 1 187 ? -102.985 29.344 311.540 1.00 26.30 ? 187 GLY A O 1 ATOM 1350 N N . ASP A 1 188 ? -102.090 30.078 313.479 1.00 26.42 ? 188 ASP A N 1 ATOM 1351 C CA . ASP A 1 188 ? -103.339 29.940 314.214 1.00 25.69 ? 188 ASP A CA 1 ATOM 1352 C C . ASP A 1 188 ? -104.395 30.883 313.652 1.00 24.67 ? 188 ASP A C 1 ATOM 1353 O O . ASP A 1 188 ? -104.122 32.052 313.366 1.00 23.24 ? 188 ASP A O 1 ATOM 1354 C CB . ASP A 1 188 ? -103.115 30.224 315.699 1.00 25.68 ? 188 ASP A CB 1 ATOM 1355 C CG . ASP A 1 188 ? -102.280 29.156 316.377 1.00 32.30 ? 188 ASP A CG 1 ATOM 1356 O OD1 . ASP A 1 188 ? -102.403 27.973 315.995 1.00 44.37 ? 188 ASP A OD1 1 ATOM 1357 O OD2 . ASP A 1 188 ? -101.502 29.499 317.291 1.00 33.27 ? 188 ASP A OD2 1 ATOM 1358 N N . GLY A 1 189 ? -105.613 30.365 313.493 1.00 26.14 ? 189 GLY A N 1 ATOM 1359 C CA . GLY A 1 189 ? -106.702 31.121 312.921 1.00 25.35 ? 189 GLY A CA 1 ATOM 1360 C C . GLY A 1 189 ? -106.750 31.137 311.410 1.00 27.15 ? 189 GLY A C 1 ATOM 1361 O O . GLY A 1 189 ? -107.822 31.374 310.842 1.00 27.51 ? 189 GLY A O 1 ATOM 1362 N N . ILE A 1 190 ? -105.628 30.889 310.737 1.00 26.25 ? 190 ILE A N 1 ATOM 1363 C CA . ILE A 1 190 ? -105.592 30.899 309.280 1.00 26.31 ? 190 ILE A CA 1 ATOM 1364 C C . ILE A 1 190 ? -105.658 29.495 308.685 1.00 38.96 ? 190 ILE A C 1 ATOM 1365 O O . ILE A 1 190 ? -106.086 29.345 307.530 1.00 26.69 ? 190 ILE A O 1 ATOM 1366 C CB . ILE A 1 190 ? -104.335 31.639 308.777 1.00 23.36 ? 190 ILE A CB 1 ATOM 1367 C CG1 . ILE A 1 190 ? -104.115 32.906 309.602 1.00 25.09 ? 190 ILE A CG1 1 ATOM 1368 C CG2 . ILE A 1 190 ? -104.468 31.996 307.305 1.00 26.84 ? 190 ILE A CG2 1 ATOM 1369 C CD1 . ILE A 1 190 ? -102.894 33.690 309.198 1.00 43.32 ? 190 ILE A CD1 1 ATOM 1370 N N . ASN A 1 191 ? -105.256 28.471 309.431 1.00 49.00 ? 191 ASN A N 1 ATOM 1371 C CA . ASN A 1 191 ? -105.355 27.090 308.970 1.00 30.78 ? 191 ASN A CA 1 ATOM 1372 C C . ASN A 1 191 ? -105.677 26.176 310.151 1.00 30.07 ? 191 ASN A C 1 ATOM 1373 O O . ASN A 1 191 ? -105.038 25.144 310.362 1.00 29.77 ? 191 ASN A O 1 ATOM 1374 C CB . ASN A 1 191 ? -104.073 26.656 308.260 1.00 27.67 ? 191 ASN A CB 1 ATOM 1375 C CG . ASN A 1 191 ? -103.974 27.200 306.851 1.00 25.87 ? 191 ASN A CG 1 ATOM 1376 O OD1 . ASN A 1 191 ? -104.661 26.731 305.945 1.00 24.66 ? 191 ASN A OD1 1 ATOM 1377 N ND2 . ASN A 1 191 ? -103.115 28.193 306.657 1.00 34.38 ? 191 ASN A ND2 1 ATOM 1378 N N . ASP A 1 192 ? -106.685 26.554 310.942 1.00 30.08 ? 192 ASP A N 1 ATOM 1379 C CA . ASP A 1 192 ? -107.106 25.720 312.062 1.00 30.68 ? 192 ASP A CA 1 ATOM 1380 C C . ASP A 1 192 ? -107.689 24.390 311.608 1.00 31.76 ? 192 ASP A C 1 ATOM 1381 O O . ASP A 1 192 ? -107.692 23.432 312.389 1.00 30.26 ? 192 ASP A O 1 ATOM 1382 C CB . ASP A 1 192 ? -108.133 26.459 312.921 1.00 30.08 ? 192 ASP A CB 1 ATOM 1383 C CG . ASP A 1 192 ? -107.582 27.735 313.520 1.00 31.08 ? 192 ASP A CG 1 ATOM 1384 O OD1 . ASP A 1 192 ? -106.343 27.881 313.575 1.00 31.57 ? 192 ASP A OD1 1 ATOM 1385 O OD2 . ASP A 1 192 ? -108.390 28.589 313.943 1.00 48.41 ? 192 ASP A OD2 1 ATOM 1386 N N . ALA A 1 193 ? -108.180 24.309 310.369 1.00 32.24 ? 193 ALA A N 1 ATOM 1387 C CA . ALA A 1 193 ? -108.764 23.064 309.883 1.00 30.10 ? 193 ALA A CA 1 ATOM 1388 C C . ALA A 1 193 ? -107.732 21.949 309.805 1.00 38.68 ? 193 ALA A C 1 ATOM 1389 O O . ALA A 1 193 ? -108.084 20.769 309.921 1.00 38.54 ? 193 ALA A O 1 ATOM 1390 C CB . ALA A 1 193 ? -109.408 23.287 308.515 1.00 29.19 ? 193 ALA A CB 1 ATOM 1391 N N . LEU A 1 194 ? -106.457 22.295 309.610 1.00 36.02 ? 194 LEU A N 1 ATOM 1392 C CA . LEU A 1 194 ? -105.412 21.280 309.582 1.00 33.01 ? 194 LEU A CA 1 ATOM 1393 C C . LEU A 1 194 ? -105.197 20.641 310.945 1.00 34.61 ? 194 LEU A C 1 ATOM 1394 O O . LEU A 1 194 ? -104.700 19.512 311.015 1.00 37.76 ? 194 LEU A O 1 ATOM 1395 C CB . LEU A 1 194 ? -104.094 21.874 309.085 1.00 34.88 ? 194 LEU A CB 1 ATOM 1396 C CG . LEU A 1 194 ? -103.923 22.089 307.581 1.00 45.44 ? 194 LEU A CG 1 ATOM 1397 C CD1 . LEU A 1 194 ? -104.723 23.289 307.109 1.00 50.76 ? 194 LEU A CD1 1 ATOM 1398 C CD2 . LEU A 1 194 ? -102.451 22.245 307.230 1.00 33.20 ? 194 LEU A CD2 1 ATOM 1399 N N . LYS A 1 195 ? -105.557 21.334 312.027 1.00 28.04 ? 195 LYS A N 1 ATOM 1400 C CA . LYS A 1 195 ? -105.425 20.766 313.362 1.00 29.30 ? 195 LYS A CA 1 ATOM 1401 C C . LYS A 1 195 ? -106.344 19.574 313.586 1.00 30.25 ? 195 LYS A C 1 ATOM 1402 O O . LYS A 1 195 ? -106.170 18.859 314.579 1.00 38.13 ? 195 LYS A O 1 ATOM 1403 C CB . LYS A 1 195 ? -105.692 21.841 314.417 1.00 29.52 ? 195 LYS A CB 1 ATOM 1404 C CG . LYS A 1 195 ? -104.753 23.032 314.320 1.00 29.60 ? 195 LYS A CG 1 ATOM 1405 C CD . LYS A 1 195 ? -105.106 24.109 315.330 1.00 28.95 ? 195 LYS A CD 1 ATOM 1406 C CE . LYS A 1 195 ? -104.066 25.216 315.330 1.00 28.09 ? 195 LYS A CE 1 ATOM 1407 N NZ . LYS A 1 195 ? -104.444 26.335 316.234 1.00 32.63 ? 195 LYS A NZ 1 ATOM 1408 N N . THR A 1 196 ? -107.313 19.344 312.696 1.00 29.05 ? 196 THR A N 1 ATOM 1409 C CA . THR A 1 196 ? -108.123 18.134 312.781 1.00 32.87 ? 196 THR A CA 1 ATOM 1410 C C . THR A 1 196 ? -107.294 16.889 312.495 1.00 34.14 ? 196 THR A C 1 ATOM 1411 O O . THR A 1 196 ? -107.635 15.797 312.963 1.00 37.37 ? 196 THR A O 1 ATOM 1412 C CB . THR A 1 196 ? -109.302 18.220 311.811 1.00 33.42 ? 196 THR A CB 1 ATOM 1413 O OG1 . THR A 1 196 ? -108.812 18.317 310.468 1.00 34.77 ? 196 THR A OG1 1 ATOM 1414 C CG2 . THR A 1 196 ? -110.157 19.439 312.121 1.00 34.75 ? 196 THR A CG2 1 ATOM 1415 N N . ILE A 1 197 ? -106.212 17.030 311.734 1.00 31.66 ? 197 ILE A N 1 ATOM 1416 C CA . ILE A 1 197 ? -105.291 15.940 311.439 1.00 29.54 ? 197 ILE A CA 1 ATOM 1417 C C . ILE A 1 197 ? -104.013 16.174 312.232 1.00 35.92 ? 197 ILE A C 1 ATOM 1418 O O . ILE A 1 197 ? -103.409 17.250 312.143 1.00 40.51 ? 197 ILE A O 1 ATOM 1419 C CB . ILE A 1 197 ? -104.994 15.842 309.933 1.00 28.02 ? 197 ILE A CB 1 ATOM 1420 C CG1 . ILE A 1 197 ? -106.296 15.720 309.140 1.00 29.81 ? 197 ILE A CG1 1 ATOM 1421 C CG2 . ILE A 1 197 ? -104.078 14.663 309.645 1.00 32.10 ? 197 ILE A CG2 1 ATOM 1422 C CD1 . ILE A 1 197 ? -106.093 15.655 307.642 1.00 29.43 ? 197 ILE A CD1 1 ATOM 1423 N N . SER A 1 198 ? -103.604 15.171 313.005 1.00 29.68 ? 198 SER A N 1 ATOM 1424 C CA . SER A 1 198 ? -102.415 15.304 313.836 1.00 32.11 ? 198 SER A CA 1 ATOM 1425 C C . SER A 1 198 ? -101.164 15.374 312.969 1.00 31.80 ? 198 SER A C 1 ATOM 1426 O O . SER A 1 198 ? -100.970 14.552 312.069 1.00 30.21 ? 198 SER A O 1 ATOM 1427 C CB . SER A 1 198 ? -102.318 14.134 314.813 1.00 39.91 ? 198 SER A CB 1 ATOM 1428 O OG . SER A 1 198 ? -101.515 13.094 314.284 1.00 54.88 ? 198 SER A OG 1 ATOM 1429 N N . GLY A 1 199 ? -100.313 16.363 313.245 1.00 33.10 ? 199 GLY A N 1 ATOM 1430 C CA . GLY A 1 199 ? -99.090 16.560 312.500 1.00 35.57 ? 199 GLY A CA 1 ATOM 1431 C C . GLY A 1 199 ? -99.243 17.286 311.183 1.00 34.82 ? 199 GLY A C 1 ATOM 1432 O O . GLY A 1 199 ? -98.239 17.746 310.626 1.00 35.02 ? 199 GLY A O 1 ATOM 1433 N N . SER A 1 200 ? -100.466 17.408 310.663 1.00 32.28 ? 200 SER A N 1 ATOM 1434 C CA . SER A 1 200 ? -100.657 18.076 309.380 1.00 31.29 ? 200 SER A CA 1 ATOM 1435 C C . SER A 1 200 ? -100.520 19.588 309.518 1.00 33.85 ? 200 SER A C 1 ATOM 1436 O O . SER A 1 200 ? -99.949 20.249 308.643 1.00 36.36 ? 200 SER A O 1 ATOM 1437 C CB . SER A 1 200 ? -102.020 17.706 308.798 1.00 31.00 ? 200 SER A CB 1 ATOM 1438 O OG . SER A 1 200 ? -102.245 18.374 307.571 1.00 34.37 ? 200 SER A OG 1 ATOM 1439 N N . PHE A 1 201 ? -101.039 20.153 310.611 1.00 36.97 ? 201 PHE A N 1 ATOM 1440 C CA . PHE A 1 201 ? -100.908 21.590 310.832 1.00 33.79 ? 201 PHE A CA 1 ATOM 1441 C C . PHE A 1 201 ? -99.459 21.977 311.094 1.00 42.79 ? 201 PHE A C 1 ATOM 1442 O O . PHE A 1 201 ? -98.975 22.988 310.571 1.00 52.31 ? 201 PHE A O 1 ATOM 1443 C CB . PHE A 1 201 ? -101.803 22.024 311.993 1.00 44.15 ? 201 PHE A CB 1 ATOM 1444 C CG . PHE A 1 201 ? -101.594 23.449 312.421 1.00 34.58 ? 201 PHE A CG 1 ATOM 1445 C CD1 . PHE A 1 201 ? -102.211 24.485 311.742 1.00 32.22 ? 201 PHE A CD1 1 ATOM 1446 C CD2 . PHE A 1 201 ? -100.793 23.751 313.510 1.00 34.95 ? 201 PHE A CD2 1 ATOM 1447 C CE1 . PHE A 1 201 ? -102.025 25.797 312.133 1.00 32.30 ? 201 PHE A CE1 1 ATOM 1448 C CE2 . PHE A 1 201 ? -100.603 25.060 313.906 1.00 33.12 ? 201 PHE A CE2 1 ATOM 1449 C CZ . PHE A 1 201 ? -101.220 26.084 313.217 1.00 32.65 ? 201 PHE A CZ 1 ATOM 1450 N N . GLU A 1 202 ? -98.751 21.186 311.902 1.00 41.27 ? 202 GLU A N 1 ATOM 1451 C CA . GLU A 1 202 ? -97.356 21.489 312.200 1.00 41.28 ? 202 GLU A CA 1 ATOM 1452 C C . GLU A 1 202 ? -96.474 21.326 310.971 1.00 37.60 ? 202 GLU A C 1 ATOM 1453 O O . GLU A 1 202 ? -95.465 22.028 310.836 1.00 37.83 ? 202 GLU A O 1 ATOM 1454 C CB . GLU A 1 202 ? -96.854 20.600 313.339 1.00 55.68 ? 202 GLU A CB 1 ATOM 1455 C CG . GLU A 1 202 ? -97.550 20.824 314.679 1.00 52.61 ? 202 GLU A CG 1 ATOM 1456 C CD . GLU A 1 202 ? -98.958 20.255 314.724 1.00 44.00 ? 202 GLU A CD 1 ATOM 1457 O OE1 . GLU A 1 202 ? -99.331 19.504 313.799 1.00 48.86 ? 202 GLU A OE1 1 ATOM 1458 O OE2 . GLU A 1 202 ? -99.695 20.565 315.683 1.00 42.35 ? 202 GLU A OE2 1 ATOM 1459 N N . SER A 1 203 ? -96.834 20.413 310.066 1.00 38.21 ? 203 SER A N 1 ATOM 1460 C CA . SER A 1 203 ? -96.053 20.234 308.848 1.00 39.52 ? 203 SER A CA 1 ATOM 1461 C C . SER A 1 203 ? -96.129 21.468 307.958 1.00 30.99 ? 203 SER A C 1 ATOM 1462 O O . SER A 1 203 ? -95.150 21.819 307.289 1.00 32.83 ? 203 SER A O 1 ATOM 1463 C CB . SER A 1 203 ? -96.535 18.996 308.092 1.00 35.36 ? 203 SER A CB 1 ATOM 1464 O OG . SER A 1 203 ? -95.635 18.651 307.053 1.00 42.98 ? 203 SER A OG 1 ATOM 1465 N N . LEU A 1 204 ? -97.281 22.142 307.939 1.00 29.99 ? 204 LEU A N 1 ATOM 1466 C CA . LEU A 1 204 ? -97.407 23.359 307.146 1.00 29.25 ? 204 LEU A CA 1 ATOM 1467 C C . LEU A 1 204 ? -96.643 24.518 307.772 1.00 29.51 ? 204 LEU A C 1 ATOM 1468 O O . LEU A 1 204 ? -96.108 25.367 307.050 1.00 39.46 ? 204 LEU A O 1 ATOM 1469 C CB . LEU A 1 204 ? -98.880 23.727 306.975 1.00 29.86 ? 204 LEU A CB 1 ATOM 1470 C CG . LEU A 1 204 ? -99.153 24.972 306.130 1.00 29.91 ? 204 LEU A CG 1 ATOM 1471 C CD1 . LEU A 1 204 ? -98.595 24.789 304.729 1.00 26.26 ? 204 LEU A CD1 1 ATOM 1472 C CD2 . LEU A 1 204 ? -100.640 25.279 306.082 1.00 58.89 ? 204 LEU A CD2 1 ATOM 1473 N N . GLN A 1 205 ? -96.580 24.571 309.104 1.00 30.26 ? 205 GLN A N 1 ATOM 1474 C CA . GLN A 1 205 ? -95.846 25.644 309.767 1.00 31.57 ? 205 GLN A CA 1 ATOM 1475 C C . GLN A 1 205 ? -94.353 25.545 309.478 1.00 33.99 ? 205 GLN A C 1 ATOM 1476 O O . GLN A 1 205 ? -93.713 26.540 309.118 1.00 28.94 ? 205 GLN A O 1 ATOM 1477 C CB . GLN A 1 205 ? -96.112 25.608 311.271 1.00 32.98 ? 205 GLN A CB 1 ATOM 1478 C CG . GLN A 1 205 ? -97.575 25.779 311.641 1.00 34.52 ? 205 GLN A CG 1 ATOM 1479 C CD . GLN A 1 205 ? -98.206 26.982 310.969 1.00 42.50 ? 205 GLN A CD 1 ATOM 1480 O OE1 . GLN A 1 205 ? -97.686 28.095 311.046 1.00 52.46 ? 205 GLN A OE1 1 ATOM 1481 N NE2 . GLN A 1 205 ? -99.335 26.764 310.305 1.00 39.47 ? 205 GLN A NE2 1 ATOM 1482 N N . ARG A 1 206 ? -93.779 24.348 309.627 1.00 31.07 ? 206 ARG A N 1 ATOM 1483 C CA . ARG A 1 206 ? -92.365 24.167 309.327 1.00 32.16 ? 206 ARG A CA 1 ATOM 1484 C C . ARG A 1 206 ? -92.081 24.231 307.833 1.00 30.96 ? 206 ARG A C 1 ATOM 1485 O O . ARG A 1 206 ? -90.923 24.415 307.443 1.00 47.93 ? 206 ARG A O 1 ATOM 1486 C CB . ARG A 1 206 ? -91.865 22.841 309.905 1.00 32.58 ? 206 ARG A CB 1 ATOM 1487 C CG . ARG A 1 206 ? -92.579 21.609 309.378 1.00 34.42 ? 206 ARG A CG 1 ATOM 1488 C CD . ARG A 1 206 ? -92.135 20.363 310.130 1.00 36.88 ? 206 ARG A CD 1 ATOM 1489 N NE . ARG A 1 206 ? -92.836 19.166 309.676 1.00 41.49 ? 206 ARG A NE 1 ATOM 1490 C CZ . ARG A 1 206 ? -92.333 18.286 308.816 1.00 38.10 ? 206 ARG A CZ 1 ATOM 1491 N NH1 . ARG A 1 206 ? -91.120 18.467 308.312 1.00 33.84 ? 206 ARG A NH1 1 ATOM 1492 N NH2 . ARG A 1 206 ? -93.043 17.225 308.460 1.00 34.33 ? 206 ARG A NH2 1 ATOM 1493 N N . SER A 1 207 ? -93.105 24.082 306.991 1.00 27.65 ? 207 SER A N 1 ATOM 1494 C CA . SER A 1 207 ? -92.929 24.305 305.561 1.00 25.51 ? 207 SER A CA 1 ATOM 1495 C C . SER A 1 207 ? -92.998 25.785 305.213 1.00 25.02 ? 207 SER A C 1 ATOM 1496 O O . SER A 1 207 ? -92.417 26.211 304.209 1.00 31.85 ? 207 SER A O 1 ATOM 1497 C CB . SER A 1 207 ? -93.980 23.528 304.768 1.00 24.06 ? 207 SER A CB 1 ATOM 1498 O OG . SER A 1 207 ? -93.806 22.131 304.921 1.00 36.06 ? 207 SER A OG 1 ATOM 1499 N N . CYS A 1 208 ? -93.701 26.576 306.024 1.00 22.28 ? 208 CYS A N 1 ATOM 1500 C CA . CYS A 1 208 ? -93.769 28.021 305.859 1.00 25.66 ? 208 CYS A CA 1 ATOM 1501 C C . CYS A 1 208 ? -92.851 28.758 306.832 1.00 26.10 ? 208 CYS A C 1 ATOM 1502 O O . CYS A 1 208 ? -93.165 29.873 307.254 1.00 27.19 ? 208 CYS A O 1 ATOM 1503 C CB . CYS A 1 208 ? -95.211 28.508 306.016 1.00 35.79 ? 208 CYS A CB 1 ATOM 1504 S SG . CYS A 1 208 ? -96.403 27.787 304.860 1.00 28.73 ? 208 CYS A SG 1 ATOM 1505 N N . LYS A 1 209 ? -91.726 28.153 307.206 1.00 27.16 ? 209 LYS A N 1 ATOM 1506 C CA . LYS A 1 209 ? -90.794 28.805 308.116 1.00 26.67 ? 209 LYS A CA 1 ATOM 1507 C C . LYS A 1 209 ? -90.063 29.924 307.384 1.00 26.53 ? 209 LYS A C 1 ATOM 1508 O O . LYS A 1 209 ? -89.512 29.713 306.298 1.00 43.21 ? 209 LYS A O 1 ATOM 1509 C CB . LYS A 1 209 ? -89.807 27.781 308.684 1.00 25.69 ? 209 LYS A CB 1 ATOM 1510 C CG . LYS A 1 209 ? -89.234 28.167 310.039 1.00 25.51 ? 209 LYS A CG 1 ATOM 1511 C CD . LYS A 1 209 ? -90.338 28.340 311.068 1.00 25.84 ? 209 LYS A CD 1 ATOM 1512 C CE . LYS A 1 209 ? -89.773 28.683 312.434 1.00 24.45 ? 209 LYS A CE 1 ATOM 1513 N NZ . LYS A 1 209 ? -90.840 28.703 313.470 1.00 37.18 ? 209 LYS A NZ 1 ATOM 1514 N N . GLY A 1 210 ? -90.073 31.123 307.969 1.00 26.73 ? 210 GLY A N 1 ATOM 1515 C CA . GLY A 1 210 ? -89.531 32.291 307.322 1.00 35.50 ? 210 GLY A CA 1 ATOM 1516 C C . GLY A 1 210 ? -90.422 32.880 306.245 1.00 29.69 ? 210 GLY A C 1 ATOM 1517 O O . GLY A 1 210 ? -90.249 34.046 305.885 1.00 37.51 ? 210 GLY A O 1 ATOM 1518 N N . ARG A 1 211 ? -91.381 32.118 305.733 1.00 30.27 ? 211 ARG A N 1 ATOM 1519 C CA . ARG A 1 211 ? -92.372 32.610 304.787 1.00 31.00 ? 211 ARG A CA 1 ATOM 1520 C C . ARG A 1 211 ? -93.624 33.009 305.554 1.00 30.70 ? 211 ARG A C 1 ATOM 1521 O O . ARG A 1 211 ? -94.147 32.220 306.347 1.00 45.66 ? 211 ARG A O 1 ATOM 1522 C CB . ARG A 1 211 ? -92.703 31.534 303.752 1.00 28.94 ? 211 ARG A CB 1 ATOM 1523 C CG . ARG A 1 211 ? -93.434 32.025 302.498 1.00 28.76 ? 211 ARG A CG 1 ATOM 1524 C CD . ARG A 1 211 ? -93.927 30.816 301.712 1.00 30.78 ? 211 ARG A CD 1 ATOM 1525 N NE . ARG A 1 211 ? -94.254 31.154 300.337 1.00 28.51 ? 211 ARG A NE 1 ATOM 1526 C CZ . ARG A 1 211 ? -93.355 31.295 299.373 1.00 30.85 ? 211 ARG A CZ 1 ATOM 1527 N NH1 . ARG A 1 211 ? -92.066 31.130 299.631 1.00 40.51 ? 211 ARG A NH1 1 ATOM 1528 N NH2 . ARG A 1 211 ? -93.750 31.613 298.152 1.00 35.22 ? 211 ARG A NH2 1 ATOM 1529 N N . GLU A 1 212 ? -94.118 34.215 305.307 1.00 30.35 ? 212 GLU A N 1 ATOM 1530 C CA . GLU A 1 212 ? -95.261 34.692 306.068 1.00 41.36 ? 212 GLU A CA 1 ATOM 1531 C C . GLU A 1 212 ? -96.567 34.480 305.303 1.00 33.13 ? 212 GLU A C 1 ATOM 1532 O O . GLU A 1 212 ? -96.584 34.106 304.130 1.00 30.32 ? 212 GLU A O 1 ATOM 1533 C CB . GLU A 1 212 ? -95.077 36.156 306.472 1.00 62.33 ? 212 GLU A CB 1 ATOM 1534 C CG . GLU A 1 212 ? -93.950 36.332 307.486 1.00 48.49 ? 212 GLU A CG 1 ATOM 1535 C CD . GLU A 1 212 ? -94.405 36.955 308.789 1.00 64.49 ? 212 GLU A CD 1 ATOM 1536 O OE1 . GLU A 1 212 ? -95.617 37.208 308.933 1.00 63.33 ? 212 GLU A OE1 1 ATOM 1537 O OE2 . GLU A 1 212 ? -93.550 37.164 309.678 1.00 54.13 ? 212 GLU A OE2 1 ATOM 1538 N N . ASP A 1 213 ? -97.671 34.747 305.997 1.00 31.69 ? 213 ASP A N 1 ATOM 1539 C CA . ASP A 1 213 ? -98.957 34.133 305.697 1.00 27.95 ? 213 ASP A CA 1 ATOM 1540 C C . ASP A 1 213 ? -99.491 34.531 304.321 1.00 29.18 ? 213 ASP A C 1 ATOM 1541 O O . ASP A 1 213 ? -99.051 35.503 303.701 1.00 29.74 ? 213 ASP A O 1 ATOM 1542 C CB . ASP A 1 213 ? -99.975 34.502 306.774 1.00 24.17 ? 213 ASP A CB 1 ATOM 1543 C CG . ASP A 1 213 ? -99.514 34.102 308.160 1.00 25.62 ? 213 ASP A CG 1 ATOM 1544 O OD1 . ASP A 1 213 ? -98.782 33.098 308.273 1.00 37.08 ? 213 ASP A OD1 1 ATOM 1545 O OD2 . ASP A 1 213 ? -99.864 34.802 309.133 1.00 25.53 ? 213 ASP A OD2 1 ATOM 1546 N N . PHE A 1 214 ? -100.454 33.734 303.846 1.00 35.62 ? 214 PHE A N 1 ATOM 1547 C CA . PHE A 1 214 ? -101.226 33.975 302.628 1.00 27.91 ? 214 PHE A CA 1 ATOM 1548 C C . PHE A 1 214 ? -100.391 33.862 301.358 1.00 28.11 ? 214 PHE A C 1 ATOM 1549 O O . PHE A 1 214 ? -100.749 34.437 300.328 1.00 26.42 ? 214 PHE A O 1 ATOM 1550 C CB . PHE A 1 214 ? -101.938 35.330 302.690 1.00 27.72 ? 214 PHE A CB 1 ATOM 1551 C CG . PHE A 1 214 ? -103.006 35.391 303.741 1.00 32.01 ? 214 PHE A CG 1 ATOM 1552 C CD1 . PHE A 1 214 ? -104.281 34.918 303.482 1.00 36.89 ? 214 PHE A CD1 1 ATOM 1553 C CD2 . PHE A 1 214 ? -102.723 35.881 305.005 1.00 37.21 ? 214 PHE A CD2 1 ATOM 1554 C CE1 . PHE A 1 214 ? -105.260 34.959 304.455 1.00 44.33 ? 214 PHE A CE1 1 ATOM 1555 C CE2 . PHE A 1 214 ? -103.697 35.921 305.983 1.00 29.08 ? 214 PHE A CE2 1 ATOM 1556 C CZ . PHE A 1 214 ? -104.967 35.462 305.707 1.00 36.33 ? 214 PHE A CZ 1 ATOM 1557 N N . LYS A 1 215 ? -99.291 33.115 301.407 1.00 27.32 ? 215 LYS A N 1 ATOM 1558 C CA . LYS A 1 215 ? -98.491 32.795 300.234 1.00 25.93 ? 215 LYS A CA 1 ATOM 1559 C C . LYS A 1 215 ? -98.551 31.297 299.982 1.00 26.74 ? 215 LYS A C 1 ATOM 1560 O O . LYS A 1 215 ? -98.602 30.502 300.927 1.00 25.10 ? 215 LYS A O 1 ATOM 1561 C CB . LYS A 1 215 ? -97.034 33.235 300.411 1.00 30.65 ? 215 LYS A CB 1 ATOM 1562 C CG . LYS A 1 215 ? -96.730 34.622 299.880 1.00 34.79 ? 215 LYS A CG 1 ATOM 1563 C CD . LYS A 1 215 ? -95.299 35.029 300.177 1.00 41.34 ? 215 LYS A CD 1 ATOM 1564 C CE . LYS A 1 215 ? -94.997 36.412 299.627 1.00 55.07 ? 215 LYS A CE 1 ATOM 1565 N NZ . LYS A 1 215 ? -93.606 36.840 299.941 1.00 67.88 ? 215 LYS A NZ 1 ATOM 1566 N N . VAL A 1 216 ? -98.545 30.912 298.705 1.00 26.93 ? 216 VAL A N 1 ATOM 1567 C CA . VAL A 1 216 ? -98.579 29.497 298.365 1.00 23.54 ? 216 VAL A CA 1 ATOM 1568 C C . VAL A 1 216 ? -97.250 28.848 298.733 1.00 27.54 ? 216 VAL A C 1 ATOM 1569 O O . VAL A 1 216 ? -96.201 29.504 298.792 1.00 31.25 ? 216 VAL A O 1 ATOM 1570 C CB . VAL A 1 216 ? -98.901 29.293 296.873 1.00 20.40 ? 216 VAL A CB 1 ATOM 1571 C CG1 . VAL A 1 216 ? -100.192 29.997 296.510 1.00 19.53 ? 216 VAL A CG1 1 ATOM 1572 C CG2 . VAL A 1 216 ? -97.755 29.784 296.004 1.00 23.85 ? 216 VAL A CG2 1 ATOM 1573 N N . ALA A 1 217 ? -97.296 27.547 298.990 1.00 21.94 ? 217 ALA A N 1 ATOM 1574 C CA . ALA A 1 217 ? -96.106 26.790 299.350 1.00 19.41 ? 217 ALA A CA 1 ATOM 1575 C C . ALA A 1 217 ? -96.366 25.323 299.017 1.00 20.38 ? 217 ALA A C 1 ATOM 1576 O O . ALA A 1 217 ? -97.216 25.010 298.177 1.00 22.62 ? 217 ALA A O 1 ATOM 1577 C CB . ALA A 1 217 ? -95.753 27.013 300.830 1.00 19.51 ? 217 ALA A CB 1 ATOM 1578 N N . ILE A 1 218 ? -95.632 24.428 299.671 1.00 19.39 ? 218 ILE A N 1 ATOM 1579 C CA . ILE A 1 218 ? -95.814 22.991 299.522 1.00 19.81 ? 218 ILE A CA 1 ATOM 1580 C C . ILE A 1 218 ? -96.000 22.396 300.909 1.00 22.58 ? 218 ILE A C 1 ATOM 1581 O O . ILE A 1 218 ? -95.216 22.682 301.820 1.00 21.78 ? 218 ILE A O 1 ATOM 1582 C CB . ILE A 1 218 ? -94.624 22.331 298.801 1.00 18.87 ? 218 ILE A CB 1 ATOM 1583 C CG1 . ILE A 1 218 ? -94.447 22.929 297.405 1.00 18.61 ? 218 ILE A CG1 1 ATOM 1584 C CG2 . ILE A 1 218 ? -94.822 20.827 298.716 1.00 30.25 ? 218 ILE A CG2 1 ATOM 1585 C CD1 . ILE A 1 218 ? -93.277 22.353 296.643 1.00 19.67 ? 218 ILE A CD1 1 ATOM 1586 N N . HIS A 1 219 ? -97.041 21.576 301.068 1.00 21.94 ? 219 HIS A N 1 ATOM 1587 C CA . HIS A 1 219 ? -97.333 20.996 302.375 1.00 24.61 ? 219 HIS A CA 1 ATOM 1588 C C . HIS A 1 219 ? -96.211 20.069 302.825 1.00 28.05 ? 219 HIS A C 1 ATOM 1589 O O . HIS A 1 219 ? -95.710 20.180 303.950 1.00 33.57 ? 219 HIS A O 1 ATOM 1590 C CB . HIS A 1 219 ? -98.666 20.250 302.328 1.00 27.81 ? 219 HIS A CB 1 ATOM 1591 C CG . HIS A 1 219 ? -99.269 20.008 303.676 1.00 28.74 ? 219 HIS A CG 1 ATOM 1592 N ND1 . HIS A 1 219 ? -100.398 19.240 303.859 1.00 27.34 ? 219 HIS A ND1 1 ATOM 1593 C CD2 . HIS A 1 219 ? -98.901 20.435 304.907 1.00 29.32 ? 219 HIS A CD2 1 ATOM 1594 C CE1 . HIS A 1 219 ? -100.700 19.203 305.144 1.00 27.89 ? 219 HIS A CE1 1 ATOM 1595 N NE2 . HIS A 1 219 ? -99.808 19.921 305.802 1.00 30.29 ? 219 HIS A NE2 1 ATOM 1596 N N . ASP A 1 220 ? -95.802 19.147 301.958 1.00 26.40 ? 220 ASP A N 1 ATOM 1597 C CA . ASP A 1 220 ? -94.714 18.218 302.252 1.00 26.70 ? 220 ASP A CA 1 ATOM 1598 C C . ASP A 1 220 ? -93.699 18.284 301.120 1.00 31.60 ? 220 ASP A C 1 ATOM 1599 O O . ASP A 1 220 ? -93.945 17.740 300.029 1.00 30.50 ? 220 ASP A O 1 ATOM 1600 C CB . ASP A 1 220 ? -95.231 16.796 302.433 1.00 26.42 ? 220 ASP A CB 1 ATOM 1601 C CG . ASP A 1 220 ? -94.137 15.825 302.825 1.00 29.73 ? 220 ASP A CG 1 ATOM 1602 O OD1 . ASP A 1 220 ? -93.088 16.279 303.330 1.00 28.88 ? 220 ASP A OD1 1 ATOM 1603 O OD2 . ASP A 1 220 ? -94.324 14.606 302.626 1.00 59.21 ? 220 ASP A OD2 1 ATOM 1604 N N . PRO A 1 221 ? -92.554 18.938 301.333 1.00 28.07 ? 221 PRO A N 1 ATOM 1605 C CA . PRO A 1 221 ? -91.538 18.998 300.272 1.00 26.68 ? 221 PRO A CA 1 ATOM 1606 C C . PRO A 1 221 ? -90.852 17.670 300.013 1.00 37.26 ? 221 PRO A C 1 ATOM 1607 O O . PRO A 1 221 ? -90.241 17.507 298.950 1.00 30.62 ? 221 PRO A O 1 ATOM 1608 C CB . PRO A 1 221 ? -90.548 20.045 300.797 1.00 26.30 ? 221 PRO A CB 1 ATOM 1609 C CG . PRO A 1 221 ? -90.678 19.955 302.281 1.00 26.87 ? 221 PRO A CG 1 ATOM 1610 C CD . PRO A 1 221 ? -92.130 19.657 302.547 1.00 27.53 ? 221 PRO A CD 1 ATOM 1611 N N . TRP A 1 222 ? -90.932 16.719 300.946 1.00 25.93 ? 222 TRP A N 1 ATOM 1612 C CA . TRP A 1 222 ? -90.299 15.420 300.741 1.00 24.07 ? 222 TRP A CA 1 ATOM 1613 C C . TRP A 1 222 ? -90.969 14.657 299.605 1.00 24.60 ? 222 TRP A C 1 ATOM 1614 O O . TRP A 1 222 ? -90.334 14.340 298.592 1.00 24.96 ? 222 TRP A O 1 ATOM 1615 C CB . TRP A 1 222 ? -90.339 14.604 302.033 1.00 29.02 ? 222 TRP A CB 1 ATOM 1616 C CG . TRP A 1 222 ? -89.888 13.191 301.845 1.00 30.29 ? 222 TRP A CG 1 ATOM 1617 C CD1 . TRP A 1 222 ? -90.674 12.076 301.818 1.00 41.19 ? 222 TRP A CD1 1 ATOM 1618 C CD2 . TRP A 1 222 ? -88.545 12.740 301.639 1.00 27.75 ? 222 TRP A CD2 1 ATOM 1619 N NE1 . TRP A 1 222 ? -89.902 10.957 301.616 1.00 35.58 ? 222 TRP A NE1 1 ATOM 1620 C CE2 . TRP A 1 222 ? -88.591 11.339 301.503 1.00 28.63 ? 222 TRP A CE2 1 ATOM 1621 C CE3 . TRP A 1 222 ? -87.307 13.385 301.561 1.00 30.87 ? 222 TRP A CE3 1 ATOM 1622 C CZ2 . TRP A 1 222 ? -87.448 10.572 301.293 1.00 30.59 ? 222 TRP A CZ2 1 ATOM 1623 C CZ3 . TRP A 1 222 ? -86.174 12.622 301.352 1.00 55.34 ? 222 TRP A CZ3 1 ATOM 1624 C CH2 . TRP A 1 222 ? -86.252 11.230 301.220 1.00 41.72 ? 222 TRP A CH2 1 ATOM 1625 N N . ALA A 1 223 ? -92.258 14.349 299.758 1.00 25.44 ? 223 ALA A N 1 ATOM 1626 C CA . ALA A 1 223 ? -92.977 13.612 298.728 1.00 25.04 ? 223 ALA A CA 1 ATOM 1627 C C . ALA A 1 223 ? -93.121 14.406 297.438 1.00 22.69 ? 223 ALA A C 1 ATOM 1628 O O . ALA A 1 223 ? -93.305 13.807 296.374 1.00 21.68 ? 223 ALA A O 1 ATOM 1629 C CB . ALA A 1 223 ? -94.357 13.206 299.242 1.00 22.15 ? 223 ALA A CB 1 ATOM 1630 N N . ALA A 1 224 ? -93.031 15.734 297.506 1.00 21.81 ? 224 ALA A N 1 ATOM 1631 C CA . ALA A 1 224 ? -93.282 16.557 296.330 1.00 20.84 ? 224 ALA A CA 1 ATOM 1632 C C . ALA A 1 224 ? -92.081 16.586 295.391 1.00 21.73 ? 224 ALA A C 1 ATOM 1633 O O . ALA A 1 224 ? -92.231 16.402 294.179 1.00 26.39 ? 224 ALA A O 1 ATOM 1634 C CB . ALA A 1 224 ? -93.662 17.975 296.755 1.00 21.74 ? 224 ALA A CB 1 ATOM 1635 N N . VAL A 1 225 ? -90.882 16.811 295.928 1.00 20.78 ? 225 VAL A N 1 ATOM 1636 C CA . VAL A 1 225 ? -89.726 17.067 295.074 1.00 20.67 ? 225 VAL A CA 1 ATOM 1637 C C . VAL A 1 225 ? -88.477 16.364 295.597 1.00 24.42 ? 225 VAL A C 1 ATOM 1638 O O . VAL A 1 225 ? -87.457 16.297 294.902 1.00 28.47 ? 225 VAL A O 1 ATOM 1639 C CB . VAL A 1 225 ? -89.484 18.582 294.939 1.00 21.74 ? 225 VAL A CB 1 ATOM 1640 C CG1 . VAL A 1 225 ? -88.781 19.121 296.175 1.00 23.41 ? 225 VAL A CG1 1 ATOM 1641 C CG2 . VAL A 1 225 ? -88.696 18.896 293.675 1.00 29.44 ? 225 VAL A CG2 1 ATOM 1642 N N . GLN A 1 226 ? -88.541 15.825 296.815 1.00 29.92 ? 226 GLN A N 1 ATOM 1643 C CA . GLN A 1 226 ? -87.368 15.226 297.442 1.00 21.51 ? 226 GLN A CA 1 ATOM 1644 C C . GLN A 1 226 ? -87.362 13.705 297.450 1.00 22.70 ? 226 GLN A C 1 ATOM 1645 O O . GLN A 1 226 ? -86.289 13.111 297.337 1.00 27.20 ? 226 GLN A O 1 ATOM 1646 C CB . GLN A 1 226 ? -87.224 15.716 298.888 1.00 21.93 ? 226 GLN A CB 1 ATOM 1647 C CG . GLN A 1 226 ? -86.965 17.203 299.026 1.00 21.97 ? 226 GLN A CG 1 ATOM 1648 C CD . GLN A 1 226 ? -86.754 17.624 300.467 1.00 22.72 ? 226 GLN A CD 1 ATOM 1649 O OE1 . GLN A 1 226 ? -87.074 16.883 301.397 1.00 26.60 ? 226 GLN A OE1 1 ATOM 1650 N NE2 . GLN A 1 226 ? -86.206 18.815 300.658 1.00 22.52 ? 226 GLN A NE2 1 ATOM 1651 N N . LYS A 1 227 ? -88.514 13.062 297.586 1.00 23.28 ? 227 LYS A N 1 ATOM 1652 C CA . LYS A 1 227 ? -88.537 11.611 297.755 1.00 29.73 ? 227 LYS A CA 1 ATOM 1653 C C . LYS A 1 227 ? -88.062 10.916 296.482 1.00 23.85 ? 227 LYS A C 1 ATOM 1654 O O . LYS A 1 227 ? -88.554 11.226 295.393 1.00 28.56 ? 227 LYS A O 1 ATOM 1655 C CB . LYS A 1 227 ? -89.939 11.134 298.123 1.00 25.64 ? 227 LYS A CB 1 ATOM 1656 C CG . LYS A 1 227 ? -90.028 9.641 298.403 1.00 22.17 ? 227 LYS A CG 1 ATOM 1657 C CD . LYS A 1 227 ? -91.430 9.237 298.824 1.00 22.81 ? 227 LYS A CD 1 ATOM 1658 C CE . LYS A 1 227 ? -91.456 7.807 299.335 1.00 20.80 ? 227 LYS A CE 1 ATOM 1659 N NZ . LYS A 1 227 ? -90.660 7.653 300.583 1.00 20.70 ? 227 LYS A NZ 1 ATOM 1660 N N . PRO A 1 228 ? -87.113 9.983 296.574 1.00 20.66 ? 228 PRO A N 1 ATOM 1661 C CA . PRO A 1 228 ? -86.662 9.264 295.374 1.00 22.45 ? 228 PRO A CA 1 ATOM 1662 C C . PRO A 1 228 ? -87.765 8.366 294.833 1.00 26.32 ? 228 PRO A C 1 ATOM 1663 O O . PRO A 1 228 ? -88.368 7.585 295.573 1.00 46.69 ? 228 PRO A O 1 ATOM 1664 C CB . PRO A 1 228 ? -85.466 8.445 295.876 1.00 23.38 ? 228 PRO A CB 1 ATOM 1665 C CG . PRO A 1 228 ? -85.064 9.085 297.169 1.00 22.97 ? 228 PRO A CG 1 ATOM 1666 C CD . PRO A 1 228 ? -86.331 9.613 297.764 1.00 23.00 ? 228 PRO A CD 1 ATOM 1667 N N . GLN A 1 229 ? -88.025 8.482 293.533 1.00 24.62 ? 229 GLN A N 1 ATOM 1668 C CA . GLN A 1 229 ? -89.051 7.698 292.860 1.00 18.60 ? 229 GLN A CA 1 ATOM 1669 C C . GLN A 1 229 ? -88.492 7.165 291.547 1.00 17.76 ? 229 GLN A C 1 ATOM 1670 O O . GLN A 1 229 ? -87.322 7.372 291.215 1.00 21.82 ? 229 GLN A O 1 ATOM 1671 C CB . GLN A 1 229 ? -90.318 8.529 292.614 1.00 17.66 ? 229 GLN A CB 1 ATOM 1672 C CG . GLN A 1 229 ? -91.002 9.032 293.876 1.00 20.95 ? 229 GLN A CG 1 ATOM 1673 C CD . GLN A 1 229 ? -91.715 7.938 294.649 1.00 21.61 ? 229 GLN A CD 1 ATOM 1674 O OE1 . GLN A 1 229 ? -91.698 6.768 294.264 1.00 22.15 ? 229 GLN A OE1 1 ATOM 1675 N NE2 . GLN A 1 229 ? -92.344 8.316 295.754 1.00 21.89 ? 229 GLN A NE2 1 ATOM 1676 N N . LYS A 1 230 ? -89.346 6.473 290.799 1.00 15.16 ? 230 LYS A N 1 ATOM 1677 C CA . LYS A 1 230 ? -88.928 5.873 289.541 1.00 15.28 ? 230 LYS A CA 1 ATOM 1678 C C . LYS A 1 230 ? -88.564 6.951 288.528 1.00 17.20 ? 230 LYS A C 1 ATOM 1679 O O . LYS A 1 230 ? -89.216 7.994 288.445 1.00 19.37 ? 230 LYS A O 1 ATOM 1680 C CB . LYS A 1 230 ? -90.040 4.968 289.004 1.00 12.55 ? 230 LYS A CB 1 ATOM 1681 C CG . LYS A 1 230 ? -89.715 4.247 287.709 1.00 12.15 ? 230 LYS A CG 1 ATOM 1682 C CD . LYS A 1 230 ? -90.650 3.070 287.468 1.00 11.11 ? 230 LYS A CD 1 ATOM 1683 C CE . LYS A 1 230 ? -90.720 2.155 288.691 1.00 18.72 ? 230 LYS A CE 1 ATOM 1684 N NZ . LYS A 1 230 ? -91.606 0.978 288.452 1.00 24.98 ? 230 LYS A NZ 1 ATOM 1685 N N . SER A 1 231 ? -87.484 6.702 287.784 1.00 16.38 ? 231 SER A N 1 ATOM 1686 C CA . SER A 1 231 ? -86.984 7.580 286.731 1.00 19.48 ? 231 SER A CA 1 ATOM 1687 C C . SER A 1 231 ? -86.448 8.891 287.298 1.00 19.54 ? 231 SER A C 1 ATOM 1688 O O . SER A 1 231 ? -85.987 9.755 286.547 1.00 18.47 ? 231 SER A O 1 ATOM 1689 C CB . SER A 1 231 ? -88.071 7.847 285.682 1.00 15.29 ? 231 SER A CB 1 ATOM 1690 O OG . SER A 1 231 ? -89.114 8.644 286.213 1.00 18.75 ? 231 SER A OG 1 ATOM 1691 N N . VAL A 1 232 ? -86.469 9.040 288.621 1.00 22.11 ? 232 VAL A N 1 ATOM 1692 C CA . VAL A 1 232 ? -85.871 10.202 289.271 1.00 27.02 ? 232 VAL A CA 1 ATOM 1693 C C . VAL A 1 232 ? -85.181 9.746 290.551 1.00 35.96 ? 232 VAL A C 1 ATOM 1694 O O . VAL A 1 232 ? -85.264 10.409 291.592 1.00 42.36 ? 232 VAL A O 1 ATOM 1695 C CB . VAL A 1 232 ? -86.922 11.291 289.559 1.00 23.59 ? 232 VAL A CB 1 ATOM 1696 C CG1 . VAL A 1 232 ? -87.202 12.098 288.299 1.00 23.13 ? 232 VAL A CG1 1 ATOM 1697 C CG2 . VAL A 1 232 ? -88.198 10.674 290.110 1.00 24.28 ? 232 VAL A CG2 1 ATOM 1698 N N . SER A 1 233 ? -84.499 8.604 290.484 1.00 28.44 ? 233 SER A N 1 ATOM 1699 C CA . SER A 1 233 ? -83.865 8.004 291.650 1.00 33.13 ? 233 SER A CA 1 ATOM 1700 C C . SER A 1 233 ? -82.371 8.289 291.732 1.00 43.68 ? 233 SER A C 1 ATOM 1701 O O . SER A 1 233 ? -81.706 7.771 292.636 1.00 45.95 ? 233 SER A O 1 ATOM 1702 C CB . SER A 1 233 ? -84.103 6.488 291.658 1.00 37.92 ? 233 SER A CB 1 ATOM 1703 O OG . SER A 1 233 ? -83.632 5.902 292.860 1.00 68.57 ? 233 SER A OG 1 ATOM 1704 N N . ALA A 1 234 ? -81.830 9.097 290.825 1.00 34.59 ? 234 ALA A N 1 ATOM 1705 C CA . ALA A 1 234 ? -80.405 9.387 290.838 1.00 36.82 ? 234 ALA A CA 1 ATOM 1706 C C . ALA A 1 234 ? -80.030 10.205 292.071 1.00 37.94 ? 234 ALA A C 1 ATOM 1707 O O . ALA A 1 234 ? -80.852 10.910 292.661 1.00 37.91 ? 234 ALA A O 1 ATOM 1708 C CB . ALA A 1 234 ? -79.994 10.132 289.567 1.00 39.44 ? 234 ALA A CB 1 ATOM 1709 N N . TRP A 1 235 ? -78.758 10.096 292.461 1.00 38.31 ? 235 TRP A N 1 ATOM 1710 C CA . TRP A 1 235 ? -78.278 10.827 293.628 1.00 42.68 ? 235 TRP A CA 1 ATOM 1711 C C . TRP A 1 235 ? -78.129 12.313 293.328 1.00 40.63 ? 235 TRP A C 1 ATOM 1712 O O . TRP A 1 235 ? -78.404 13.157 294.190 1.00 43.71 ? 235 TRP A O 1 ATOM 1713 C CB . TRP A 1 235 ? -76.954 10.231 294.105 1.00 46.63 ? 235 TRP A CB 1 ATOM 1714 C CG . TRP A 1 235 ? -75.870 10.283 293.074 1.00 59.86 ? 235 TRP A CG 1 ATOM 1715 C CD1 . TRP A 1 235 ? -75.647 9.380 292.075 1.00 67.59 ? 235 TRP A CD1 1 ATOM 1716 C CD2 . TRP A 1 235 ? -74.852 11.282 292.946 1.00 53.86 ? 235 TRP A CD2 1 ATOM 1717 N NE1 . TRP A 1 235 ? -74.558 9.759 291.329 1.00 57.68 ? 235 TRP A NE1 1 ATOM 1718 C CE2 . TRP A 1 235 ? -74.051 10.923 291.844 1.00 50.57 ? 235 TRP A CE2 1 ATOM 1719 C CE3 . TRP A 1 235 ? -74.542 12.447 293.655 1.00 51.60 ? 235 TRP A CE3 1 ATOM 1720 C CZ2 . TRP A 1 235 ? -72.961 11.687 291.434 1.00 55.87 ? 235 TRP A CZ2 1 ATOM 1721 C CZ3 . TRP A 1 235 ? -73.459 13.203 293.246 1.00 53.73 ? 235 TRP A CZ3 1 ATOM 1722 C CH2 . TRP A 1 235 ? -72.681 12.819 292.147 1.00 53.45 ? 235 TRP A CH2 1 ATOM 1723 N N . ASN A 1 236 ? -77.697 12.654 292.115 1.00 39.89 ? 236 ASN A N 1 ATOM 1724 C CA . ASN A 1 236 ? -77.597 14.038 291.678 1.00 40.90 ? 236 ASN A CA 1 ATOM 1725 C C . ASN A 1 236 ? -78.847 14.505 290.944 1.00 39.53 ? 236 ASN A C 1 ATOM 1726 O O . ASN A 1 236 ? -78.775 15.460 290.160 1.00 36.13 ? 236 ASN A O 1 ATOM 1727 C CB . ASN A 1 236 ? -76.369 14.222 290.787 1.00 46.96 ? 236 ASN A CB 1 ATOM 1728 C CG . ASN A 1 236 ? -76.376 13.296 289.588 1.00 44.34 ? 236 ASN A CG 1 ATOM 1729 O OD1 . ASN A 1 236 ? -77.055 12.270 289.586 1.00 42.67 ? 236 ASN A OD1 1 ATOM 1730 N ND2 . ASN A 1 236 ? -75.620 13.655 288.558 1.00 51.03 ? 236 ASN A ND2 1 ATOM 1731 N N . GLU A 1 237 ? -79.978 13.853 291.174 1.00 54.95 ? 237 GLU A N 1 ATOM 1732 C CA . GLU A 1 237 ? -81.211 14.192 290.474 1.00 35.95 ? 237 GLU A CA 1 ATOM 1733 C C . GLU A 1 237 ? -81.663 15.592 290.863 1.00 32.73 ? 237 GLU A C 1 ATOM 1734 O O . GLU A 1 237 ? -81.888 15.852 292.053 1.00 45.40 ? 237 GLU A O 1 ATOM 1735 C CB . GLU A 1 237 ? -82.298 13.173 290.798 1.00 31.76 ? 237 GLU A CB 1 ATOM 1736 C CG . GLU A 1 237 ? -83.458 13.172 289.819 1.00 48.51 ? 237 GLU A CG 1 ATOM 1737 C CD . GLU A 1 237 ? -83.011 12.941 288.389 1.00 34.63 ? 237 GLU A CD 1 ATOM 1738 O OE1 . GLU A 1 237 ? -82.327 11.929 288.136 1.00 39.94 ? 237 GLU A OE1 1 ATOM 1739 O OE2 . GLU A 1 237 ? -83.345 13.772 287.519 1.00 49.16 ? 237 GLU A OE2 1 ATOM 1740 N N . PRO A 1 238 ? -81.800 16.519 289.912 1.00 30.70 ? 238 PRO A N 1 ATOM 1741 C CA . PRO A 1 238 ? -82.226 17.879 290.282 1.00 30.09 ? 238 PRO A CA 1 ATOM 1742 C C . PRO A 1 238 ? -83.632 17.933 290.852 1.00 32.11 ? 238 PRO A C 1 ATOM 1743 O O . PRO A 1 238 ? -83.891 18.713 291.776 1.00 32.86 ? 238 PRO A O 1 ATOM 1744 C CB . PRO A 1 238 ? -82.117 18.651 288.959 1.00 26.71 ? 238 PRO A CB 1 ATOM 1745 C CG . PRO A 1 238 ? -81.222 17.818 288.088 1.00 33.12 ? 238 PRO A CG 1 ATOM 1746 C CD . PRO A 1 238 ? -81.488 16.403 288.480 1.00 32.28 ? 238 PRO A CD 1 ATOM 1747 N N . TYR A 1 239 ? -84.549 17.119 290.332 1.00 28.67 ? 239 TYR A N 1 ATOM 1748 C CA . TYR A 1 239 ? -85.937 17.117 290.778 1.00 25.51 ? 239 TYR A CA 1 ATOM 1749 C C . TYR A 1 239 ? -86.396 15.680 290.964 1.00 27.14 ? 239 TYR A C 1 ATOM 1750 O O . TYR A 1 239 ? -86.348 14.883 290.021 1.00 28.03 ? 239 TYR A O 1 ATOM 1751 C CB . TYR A 1 239 ? -86.838 17.844 289.777 1.00 24.97 ? 239 TYR A CB 1 ATOM 1752 C CG . TYR A 1 239 ? -86.334 19.215 289.388 1.00 27.59 ? 239 TYR A CG 1 ATOM 1753 C CD1 . TYR A 1 239 ? -86.310 20.254 290.309 1.00 27.81 ? 239 TYR A CD1 1 ATOM 1754 C CD2 . TYR A 1 239 ? -85.880 19.470 288.101 1.00 25.98 ? 239 TYR A CD2 1 ATOM 1755 C CE1 . TYR A 1 239 ? -85.848 21.508 289.959 1.00 26.26 ? 239 TYR A CE1 1 ATOM 1756 C CE2 . TYR A 1 239 ? -85.417 20.721 287.742 1.00 26.38 ? 239 TYR A CE2 1 ATOM 1757 C CZ . TYR A 1 239 ? -85.403 21.736 288.674 1.00 25.35 ? 239 TYR A CZ 1 ATOM 1758 O OH . TYR A 1 239 ? -84.943 22.984 288.321 1.00 22.18 ? 239 TYR A OH 1 ATOM 1759 N N . LYS A 1 240 ? -86.838 15.352 292.178 1.00 29.17 ? 240 LYS A N 1 ATOM 1760 C CA . LYS A 1 240 ? -87.384 14.032 292.469 1.00 24.79 ? 240 LYS A CA 1 ATOM 1761 C C . LYS A 1 240 ? -88.846 14.152 292.879 1.00 26.57 ? 240 LYS A C 1 ATOM 1762 O O . LYS A 1 240 ? -89.523 15.116 292.506 1.00 21.71 ? 240 LYS A O 1 ATOM 1763 C CB . LYS A 1 240 ? -86.576 13.342 293.570 1.00 23.19 ? 240 LYS A CB 1 ATOM 1764 C CG . LYS A 1 240 ? -85.073 13.355 293.349 1.00 26.00 ? 240 LYS A CG 1 ATOM 1765 C CD . LYS A 1 240 ? -84.345 12.669 294.496 1.00 30.89 ? 240 LYS A CD 1 ATOM 1766 C CE . LYS A 1 240 ? -82.839 12.843 294.382 1.00 35.20 ? 240 LYS A CE 1 ATOM 1767 N NZ . LYS A 1 240 ? -82.129 12.375 295.605 1.00 46.06 ? 240 LYS A NZ 1 ATOM 1768 N N . GLY A 1 241 ? -89.339 13.180 293.643 1.00 27.48 ? 241 GLY A N 1 ATOM 1769 C CA . GLY A 1 241 ? -90.677 13.230 294.197 1.00 22.73 ? 241 GLY A CA 1 ATOM 1770 C C . GLY A 1 241 ? -91.775 13.255 293.142 1.00 19.03 ? 241 GLY A C 1 ATOM 1771 O O . GLY A 1 241 ? -91.591 12.869 291.985 1.00 15.68 ? 241 GLY A O 1 ATOM 1772 N N . ASN A 1 242 ? -92.945 13.727 293.578 1.00 16.88 ? 242 ASN A N 1 ATOM 1773 C CA . ASN A 1 242 ? -94.089 13.817 292.677 1.00 17.01 ? 242 ASN A CA 1 ATOM 1774 C C . ASN A 1 242 ? -93.849 14.842 291.577 1.00 18.09 ? 242 ASN A C 1 ATOM 1775 O O . ASN A 1 242 ? -94.229 14.621 290.422 1.00 17.20 ? 242 ASN A O 1 ATOM 1776 C CB . ASN A 1 242 ? -95.353 14.166 293.463 1.00 16.45 ? 242 ASN A CB 1 ATOM 1777 C CG . ASN A 1 242 ? -95.636 13.180 294.577 1.00 15.52 ? 242 ASN A CG 1 ATOM 1778 O OD1 . ASN A 1 242 ? -95.237 12.019 294.509 1.00 24.28 ? 242 ASN A OD1 1 ATOM 1779 N ND2 . ASN A 1 242 ? -96.327 13.640 295.613 1.00 11.88 ? 242 ASN A ND2 1 ATOM 1780 N N . PHE A 1 243 ? -93.217 15.969 291.915 1.00 20.08 ? 243 PHE A N 1 ATOM 1781 C CA . PHE A 1 243 ? -92.997 17.016 290.922 1.00 23.23 ? 243 PHE A CA 1 ATOM 1782 C C . PHE A 1 243 ? -92.038 16.556 289.832 1.00 25.28 ? 243 PHE A C 1 ATOM 1783 O O . PHE A 1 243 ? -92.261 16.830 288.647 1.00 50.47 ? 243 PHE A O 1 ATOM 1784 C CB . PHE A 1 243 ? -92.472 18.282 291.597 1.00 24.21 ? 243 PHE A CB 1 ATOM 1785 C CG . PHE A 1 243 ? -93.537 19.097 292.273 1.00 23.00 ? 243 PHE A CG 1 ATOM 1786 C CD1 . PHE A 1 243 ? -94.852 18.665 292.297 1.00 21.19 ? 243 PHE A CD1 1 ATOM 1787 C CD2 . PHE A 1 243 ? -93.223 20.303 292.873 1.00 22.58 ? 243 PHE A CD2 1 ATOM 1788 C CE1 . PHE A 1 243 ? -95.832 19.417 292.915 1.00 19.34 ? 243 PHE A CE1 1 ATOM 1789 C CE2 . PHE A 1 243 ? -94.198 21.060 293.492 1.00 22.37 ? 243 PHE A CE2 1 ATOM 1790 C CZ . PHE A 1 243 ? -95.503 20.616 293.513 1.00 20.16 ? 243 PHE A CZ 1 ATOM 1791 N N . GLY A 1 244 ? -90.966 15.858 290.211 1.00 20.55 ? 244 GLY A N 1 ATOM 1792 C CA . GLY A 1 244 ? -90.009 15.398 289.217 1.00 23.93 ? 244 GLY A CA 1 ATOM 1793 C C . GLY A 1 244 ? -90.609 14.405 288.240 1.00 29.95 ? 244 GLY A C 1 ATOM 1794 O O . GLY A 1 244 ? -90.344 14.466 287.037 1.00 29.95 ? 244 GLY A O 1 ATOM 1795 N N . GLN A 1 245 ? -91.428 13.479 288.743 1.00 23.46 ? 245 GLN A N 1 ATOM 1796 C CA . GLN A 1 245 ? -92.064 12.504 287.863 1.00 19.45 ? 245 GLN A CA 1 ATOM 1797 C C . GLN A 1 245 ? -93.061 13.171 286.926 1.00 17.12 ? 245 GLN A C 1 ATOM 1798 O O . GLN A 1 245 ? -93.178 12.782 285.758 1.00 16.64 ? 245 GLN A O 1 ATOM 1799 C CB . GLN A 1 245 ? -92.750 11.417 288.690 1.00 16.69 ? 245 GLN A CB 1 ATOM 1800 C CG . GLN A 1 245 ? -91.797 10.418 289.319 1.00 17.45 ? 245 GLN A CG 1 ATOM 1801 C CD . GLN A 1 245 ? -92.523 9.278 290.005 1.00 14.74 ? 245 GLN A CD 1 ATOM 1802 O OE1 . GLN A 1 245 ? -93.487 9.494 290.740 1.00 15.40 ? 245 GLN A OE1 1 ATOM 1803 N NE2 . GLN A 1 245 ? -92.067 8.056 289.763 1.00 13.83 ? 245 GLN A NE2 1 ATOM 1804 N N . LEU A 1 246 ? -93.787 14.179 287.416 1.00 19.15 ? 246 LEU A N 1 ATOM 1805 C CA . LEU A 1 246 ? -94.759 14.866 286.571 1.00 22.73 ? 246 LEU A CA 1 ATOM 1806 C C . LEU A 1 246 ? -94.082 15.608 285.425 1.00 21.55 ? 246 LEU A C 1 ATOM 1807 O O . LEU A 1 246 ? -94.690 15.791 284.364 1.00 18.88 ? 246 LEU A O 1 ATOM 1808 C CB . LEU A 1 246 ? -95.600 15.828 287.410 1.00 16.14 ? 246 LEU A CB 1 ATOM 1809 C CG . LEU A 1 246 ? -96.593 15.187 288.384 1.00 15.15 ? 246 LEU A CG 1 ATOM 1810 C CD1 . LEU A 1 246 ? -97.172 16.228 289.330 1.00 13.92 ? 246 LEU A CD1 1 ATOM 1811 C CD2 . LEU A 1 246 ? -97.701 14.458 287.642 1.00 15.48 ? 246 LEU A CD2 1 ATOM 1812 N N . MET A 1 247 ? -92.834 16.042 285.616 1.00 18.64 ? 247 MET A N 1 ATOM 1813 C CA . MET A 1 247 ? -92.085 16.641 284.516 1.00 18.07 ? 247 MET A CA 1 ATOM 1814 C C . MET A 1 247 ? -91.810 15.614 283.426 1.00 17.18 ? 247 MET A C 1 ATOM 1815 O O . MET A 1 247 ? -92.034 15.877 282.238 1.00 18.57 ? 247 MET A O 1 ATOM 1816 C CB . MET A 1 247 ? -90.772 17.234 285.028 1.00 21.93 ? 247 MET A CB 1 ATOM 1817 C CG . MET A 1 247 ? -90.921 18.229 286.162 1.00 19.64 ? 247 MET A CG 1 ATOM 1818 S SD . MET A 1 247 ? -89.324 18.719 286.835 1.00 15.77 ? 247 MET A SD 1 ATOM 1819 C CE . MET A 1 247 ? -89.832 19.598 288.309 1.00 20.19 ? 247 MET A CE 1 ATOM 1820 N N . ALA A 1 248 ? -91.322 14.434 283.814 1.00 16.86 ? 248 ALA A N 1 ATOM 1821 C CA . ALA A 1 248 ? -91.039 13.391 282.836 1.00 18.22 ? 248 ALA A CA 1 ATOM 1822 C C . ALA A 1 248 ? -92.317 12.766 282.293 1.00 19.77 ? 248 ALA A C 1 ATOM 1823 O O . ALA A 1 248 ? -92.323 12.246 281.172 1.00 20.47 ? 248 ALA A O 1 ATOM 1824 C CB . ALA A 1 248 ? -90.147 12.318 283.459 1.00 18.69 ? 248 ALA A CB 1 ATOM 1825 N N . ALA A 1 249 ? -93.402 12.808 283.068 1.00 20.91 ? 249 ALA A N 1 ATOM 1826 C CA . ALA A 1 249 ? -94.655 12.212 282.619 1.00 19.59 ? 249 ALA A CA 1 ATOM 1827 C C . ALA A 1 249 ? -95.277 13.015 281.484 1.00 19.14 ? 249 ALA A C 1 ATOM 1828 O O . ALA A 1 249 ? -95.835 12.438 280.543 1.00 17.74 ? 249 ALA A O 1 ATOM 1829 C CB . ALA A 1 249 ? -95.627 12.095 283.791 1.00 18.36 ? 249 ALA A CB 1 ATOM 1830 N N . LYS A 1 250 ? -95.193 14.346 281.554 1.00 19.05 ? 250 LYS A N 1 ATOM 1831 C CA . LYS A 1 250 ? -95.725 15.182 280.483 1.00 20.79 ? 250 LYS A CA 1 ATOM 1832 C C . LYS A 1 250 ? -95.004 14.954 279.163 1.00 21.18 ? 250 LYS A C 1 ATOM 1833 O O . LYS A 1 250 ? -95.566 15.248 278.103 1.00 22.79 ? 250 LYS A O 1 ATOM 1834 C CB . LYS A 1 250 ? -95.640 16.658 280.871 1.00 22.79 ? 250 LYS A CB 1 ATOM 1835 C CG . LYS A 1 250 ? -96.613 17.066 281.960 1.00 28.39 ? 250 LYS A CG 1 ATOM 1836 C CD . LYS A 1 250 ? -96.689 18.578 282.099 1.00 26.07 ? 250 LYS A CD 1 ATOM 1837 C CE . LYS A 1 250 ? -97.144 19.230 280.804 1.00 29.67 ? 250 LYS A CE 1 ATOM 1838 N NZ . LYS A 1 250 ? -97.236 20.711 280.932 1.00 27.62 ? 250 LYS A NZ 1 ATOM 1839 N N . LEU A 1 251 ? -93.773 14.443 279.202 1.00 22.83 ? 251 LEU A N 1 ATOM 1840 C CA . LEU A 1 251 ? -93.068 14.116 277.969 1.00 21.45 ? 251 LEU A CA 1 ATOM 1841 C C . LEU A 1 251 ? -93.593 12.822 277.361 1.00 21.61 ? 251 LEU A C 1 ATOM 1842 O O . LEU A 1 251 ? -93.765 12.731 276.140 1.00 26.83 ? 251 LEU A O 1 ATOM 1843 C CB . LEU A 1 251 ? -91.567 14.014 278.237 1.00 19.35 ? 251 LEU A CB 1 ATOM 1844 C CG . LEU A 1 251 ? -90.942 15.231 278.919 1.00 18.32 ? 251 LEU A CG 1 ATOM 1845 C CD1 . LEU A 1 251 ? -89.477 14.977 279.223 1.00 46.18 ? 251 LEU A CD1 1 ATOM 1846 C CD2 . LEU A 1 251 ? -91.110 16.472 278.058 1.00 25.59 ? 251 LEU A CD2 1 ATOM 1847 N N . ALA A 1 252 ? -93.851 11.812 278.195 1.00 19.77 ? 252 ALA A N 1 ATOM 1848 C CA . ALA A 1 252 ? -94.449 10.579 277.698 1.00 16.81 ? 252 ALA A CA 1 ATOM 1849 C C . ALA A 1 252 ? -95.923 10.767 277.370 1.00 17.75 ? 252 ALA A C 1 ATOM 1850 O O . ALA A 1 252 ? -96.465 10.051 276.521 1.00 20.62 ? 252 ALA A O 1 ATOM 1851 C CB . ALA A 1 252 ? -94.272 9.457 278.720 1.00 18.49 ? 252 ALA A CB 1 ATOM 1852 N N . ASN A 1 253 ? -96.585 11.721 278.028 1.00 19.16 ? 253 ASN A N 1 ATOM 1853 C CA . ASN A 1 253 ? -97.989 12.041 277.787 1.00 18.74 ? 253 ASN A CA 1 ATOM 1854 C C . ASN A 1 253 ? -98.076 13.514 277.404 1.00 20.40 ? 253 ASN A C 1 ATOM 1855 O O . ASN A 1 253 ? -98.421 14.364 278.239 1.00 31.30 ? 253 ASN A O 1 ATOM 1856 C CB . ASN A 1 253 ? -98.849 11.736 279.013 1.00 16.13 ? 253 ASN A CB 1 ATOM 1857 C CG . ASN A 1 253 ? -98.677 10.313 279.505 1.00 17.11 ? 253 ASN A CG 1 ATOM 1858 O OD1 . ASN A 1 253 ? -99.336 9.393 279.022 1.00 31.91 ? 253 ASN A OD1 1 ATOM 1859 N ND2 . ASN A 1 253 ? -97.788 10.126 280.473 1.00 15.75 ? 253 ASN A ND2 1 ATOM 1860 N N . PRO A 1 254 ? -97.765 13.855 276.151 1.00 21.55 ? 254 PRO A N 1 ATOM 1861 C CA . PRO A 1 254 ? -97.836 15.268 275.748 1.00 20.94 ? 254 PRO A CA 1 ATOM 1862 C C . PRO A 1 254 ? -99.251 15.813 275.744 1.00 20.29 ? 254 PRO A C 1 ATOM 1863 O O . PRO A 1 254 ? -99.437 17.026 275.903 1.00 34.94 ? 254 PRO A O 1 ATOM 1864 C CB . PRO A 1 254 ? -97.224 15.260 274.342 1.00 19.22 ? 254 PRO A CB 1 ATOM 1865 C CG . PRO A 1 254 ? -97.514 13.888 273.831 1.00 25.30 ? 254 PRO A CG 1 ATOM 1866 C CD . PRO A 1 254 ? -97.403 12.977 275.025 1.00 26.00 ? 254 PRO A CD 1 ATOM 1867 N N . HIS A 1 255 ? -100.255 14.952 275.568 1.00 18.72 ? 255 HIS A N 1 ATOM 1868 C CA . HIS A 1 255 ? -101.640 15.399 275.654 1.00 18.83 ? 255 HIS A CA 1 ATOM 1869 C C . HIS A 1 255 ? -101.997 15.843 277.065 1.00 19.29 ? 255 HIS A C 1 ATOM 1870 O O . HIS A 1 255 ? -102.856 16.714 277.242 1.00 20.52 ? 255 HIS A O 1 ATOM 1871 C CB . HIS A 1 255 ? -102.576 14.274 275.218 1.00 21.66 ? 255 HIS A CB 1 ATOM 1872 C CG . HIS A 1 255 ? -102.687 13.168 276.220 1.00 20.45 ? 255 HIS A CG 1 ATOM 1873 N ND1 . HIS A 1 255 ? -101.820 12.097 276.246 1.00 29.14 ? 255 HIS A ND1 1 ATOM 1874 C CD2 . HIS A 1 255 ? -103.555 12.975 277.242 1.00 21.36 ? 255 HIS A CD2 1 ATOM 1875 C CE1 . HIS A 1 255 ? -102.152 11.289 277.237 1.00 24.21 ? 255 HIS A CE1 1 ATOM 1876 N NE2 . HIS A 1 255 ? -103.202 11.798 277.856 1.00 21.42 ? 255 HIS A NE2 1 ATOM 1877 N N . LEU A 1 256 ? -101.351 15.259 278.071 1.00 21.53 ? 256 LEU A N 1 ATOM 1878 C CA . LEU A 1 256 ? -101.741 15.483 279.454 1.00 30.03 ? 256 LEU A CA 1 ATOM 1879 C C . LEU A 1 256 ? -101.481 16.924 279.874 1.00 24.14 ? 256 LEU A C 1 ATOM 1880 O O . LEU A 1 256 ? -100.452 17.515 279.535 1.00 24.24 ? 256 LEU A O 1 ATOM 1881 C CB . LEU A 1 256 ? -100.985 14.528 280.377 1.00 24.34 ? 256 LEU A CB 1 ATOM 1882 C CG . LEU A 1 256 ? -101.207 14.723 281.877 1.00 20.62 ? 256 LEU A CG 1 ATOM 1883 C CD1 . LEU A 1 256 ? -102.579 14.210 282.292 1.00 19.55 ? 256 LEU A CD1 1 ATOM 1884 C CD2 . LEU A 1 256 ? -100.107 14.049 282.675 1.00 19.23 ? 256 LEU A CD2 1 ATOM 1885 N N . LYS A 1 257 ? -102.430 17.485 280.616 1.00 23.00 ? 257 LYS A N 1 ATOM 1886 C CA . LYS A 1 257 ? -102.317 18.811 281.204 1.00 20.45 ? 257 LYS A CA 1 ATOM 1887 C C . LYS A 1 257 ? -102.466 18.685 282.713 1.00 16.94 ? 257 LYS A C 1 ATOM 1888 O O . LYS A 1 257 ? -103.396 18.031 283.196 1.00 17.84 ? 257 LYS A O 1 ATOM 1889 C CB . LYS A 1 257 ? -103.375 19.750 280.623 1.00 25.62 ? 257 LYS A CB 1 ATOM 1890 C CG . LYS A 1 257 ? -103.532 19.616 279.114 1.00 44.83 ? 257 LYS A CG 1 ATOM 1891 C CD . LYS A 1 257 ? -104.553 20.595 278.564 1.00 38.89 ? 257 LYS A CD 1 ATOM 1892 C CE . LYS A 1 257 ? -105.881 20.449 279.285 1.00 36.98 ? 257 LYS A CE 1 ATOM 1893 N NZ . LYS A 1 257 ? -106.335 19.032 279.306 1.00 80.15 ? 257 LYS A NZ 1 ATOM 1894 N N . ILE A 1 258 ? -101.547 19.298 283.453 1.00 16.32 ? 258 ILE A N 1 ATOM 1895 C CA . ILE A 1 258 ? -101.481 19.167 284.903 1.00 15.45 ? 258 ILE A CA 1 ATOM 1896 C C . ILE A 1 258 ? -101.861 20.500 285.529 1.00 16.16 ? 258 ILE A C 1 ATOM 1897 O O . ILE A 1 258 ? -101.389 21.556 285.091 1.00 17.28 ? 258 ILE A O 1 ATOM 1898 C CB . ILE A 1 258 ? -100.083 18.719 285.360 1.00 14.62 ? 258 ILE A CB 1 ATOM 1899 C CG1 . ILE A 1 258 ? -99.699 17.413 284.668 1.00 13.81 ? 258 ILE A CG1 1 ATOM 1900 C CG2 . ILE A 1 258 ? -100.044 18.549 286.870 1.00 12.24 ? 258 ILE A CG2 1 ATOM 1901 C CD1 . ILE A 1 258 ? -98.357 16.879 285.088 1.00 15.91 ? 258 ILE A CD1 1 ATOM 1902 N N . LEU A 1 259 ? -102.713 20.449 286.551 1.00 18.55 ? 259 LEU A N 1 ATOM 1903 C CA . LEU A 1 259 ? -103.178 21.642 287.234 1.00 20.31 ? 259 LEU A CA 1 ATOM 1904 C C . LEU A 1 259 ? -102.935 21.515 288.731 1.00 18.82 ? 259 LEU A C 1 ATOM 1905 O O . LEU A 1 259 ? -103.196 20.458 289.317 1.00 16.42 ? 259 LEU A O 1 ATOM 1906 C CB . LEU A 1 259 ? -104.673 21.876 286.974 1.00 20.55 ? 259 LEU A CB 1 ATOM 1907 C CG . LEU A 1 259 ? -105.071 22.179 285.530 1.00 21.73 ? 259 LEU A CG 1 ATOM 1908 C CD1 . LEU A 1 259 ? -106.580 22.324 285.409 1.00 26.73 ? 259 LEU A CD1 1 ATOM 1909 C CD2 . LEU A 1 259 ? -104.364 23.424 285.027 1.00 18.71 ? 259 LEU A CD2 1 ATOM 1910 N N . PRO A 1 260 ? -102.431 22.568 289.374 1.00 18.10 ? 260 PRO A N 1 ATOM 1911 C CA . PRO A 1 260 ? -102.248 22.527 290.829 1.00 17.13 ? 260 PRO A CA 1 ATOM 1912 C C . PRO A 1 260 ? -103.515 22.907 291.578 1.00 18.27 ? 260 PRO A C 1 ATOM 1913 O O . PRO A 1 260 ? -104.074 23.988 291.364 1.00 18.46 ? 260 PRO A O 1 ATOM 1914 C CB . PRO A 1 260 ? -101.126 23.543 291.061 1.00 16.48 ? 260 PRO A CB 1 ATOM 1915 C CG . PRO A 1 260 ? -101.336 24.553 289.978 1.00 18.44 ? 260 PRO A CG 1 ATOM 1916 C CD . PRO A 1 260 ? -101.870 23.794 288.781 1.00 18.26 ? 260 PRO A CD 1 ATOM 1917 N N . SER A 1 261 ? -103.979 22.024 292.457 1.00 15.91 ? 261 SER A N 1 ATOM 1918 C CA . SER A 1 261 ? -105.198 22.258 293.222 1.00 17.13 ? 261 SER A CA 1 ATOM 1919 C C . SER A 1 261 ? -104.837 22.991 294.508 1.00 17.01 ? 261 SER A C 1 ATOM 1920 O O . SER A 1 261 ? -104.174 22.431 295.388 1.00 16.67 ? 261 SER A O 1 ATOM 1921 C CB . SER A 1 261 ? -105.914 20.942 293.513 1.00 20.04 ? 261 SER A CB 1 ATOM 1922 O OG . SER A 1 261 ? -106.560 20.451 292.351 1.00 25.75 ? 261 SER A OG 1 ATOM 1923 N N . ILE A 1 262 ? -105.269 24.242 294.614 1.00 17.09 ? 262 ILE A N 1 ATOM 1924 C CA . ILE A 1 262 ? -105.005 25.075 295.780 1.00 16.68 ? 262 ILE A CA 1 ATOM 1925 C C . ILE A 1 262 ? -106.202 24.967 296.713 1.00 20.06 ? 262 ILE A C 1 ATOM 1926 O O . ILE A 1 262 ? -107.299 25.435 296.388 1.00 22.31 ? 262 ILE A O 1 ATOM 1927 C CB . ILE A 1 262 ? -104.740 26.533 295.383 1.00 17.10 ? 262 ILE A CB 1 ATOM 1928 C CG1 . ILE A 1 262 ? -103.655 26.608 294.307 1.00 22.23 ? 262 ILE A CG1 1 ATOM 1929 C CG2 . ILE A 1 262 ? -104.350 27.351 296.599 1.00 16.69 ? 262 ILE A CG2 1 ATOM 1930 C CD1 . ILE A 1 262 ? -103.344 28.021 293.863 1.00 17.12 ? 262 ILE A CD1 1 ATOM 1931 N N . GLY A 1 263 ? -105.998 24.358 297.877 1.00 19.43 ? 263 GLY A N 1 ATOM 1932 C CA . GLY A 1 263 ? -107.051 24.274 298.869 1.00 18.89 ? 263 GLY A CA 1 ATOM 1933 C C . GLY A 1 263 ? -107.419 22.860 299.265 1.00 21.39 ? 263 GLY A C 1 ATOM 1934 O O . GLY A 1 263 ? -106.578 22.101 299.753 1.00 20.83 ? 263 GLY A O 1 ATOM 1935 N N . GLY A 1 264 ? -108.674 22.494 299.052 1.00 20.56 ? 264 GLY A N 1 ATOM 1936 C CA . GLY A 1 264 ? -109.180 21.213 299.490 1.00 20.22 ? 264 GLY A CA 1 ATOM 1937 C C . GLY A 1 264 ? -110.055 21.339 300.719 1.00 24.16 ? 264 GLY A C 1 ATOM 1938 O O . GLY A 1 264 ? -110.522 22.418 301.087 1.00 24.84 ? 264 GLY A O 1 ATOM 1939 N N . TRP A 1 265 ? -110.273 20.197 301.371 1.00 25.63 ? 265 TRP A N 1 ATOM 1940 C CA . TRP A 1 265 ? -111.130 20.188 302.551 1.00 27.66 ? 265 TRP A CA 1 ATOM 1941 C C . TRP A 1 265 ? -110.457 20.873 303.734 1.00 25.26 ? 265 TRP A C 1 ATOM 1942 O O . TRP A 1 265 ? -111.092 21.659 304.446 1.00 31.26 ? 265 TRP A O 1 ATOM 1943 C CB . TRP A 1 265 ? -111.518 18.754 302.912 1.00 27.03 ? 265 TRP A CB 1 ATOM 1944 C CG . TRP A 1 265 ? -112.343 18.659 304.159 1.00 28.74 ? 265 TRP A CG 1 ATOM 1945 C CD1 . TRP A 1 265 ? -111.939 18.192 305.375 1.00 30.75 ? 265 TRP A CD1 1 ATOM 1946 C CD2 . TRP A 1 265 ? -113.712 19.050 304.314 1.00 29.77 ? 265 TRP A CD2 1 ATOM 1947 N NE1 . TRP A 1 265 ? -112.972 18.263 306.277 1.00 32.57 ? 265 TRP A NE1 1 ATOM 1948 C CE2 . TRP A 1 265 ? -114.072 18.787 305.651 1.00 35.40 ? 265 TRP A CE2 1 ATOM 1949 C CE3 . TRP A 1 265 ? -114.669 19.595 303.453 1.00 34.04 ? 265 TRP A CE3 1 ATOM 1950 C CZ2 . TRP A 1 265 ? -115.347 19.051 306.146 1.00 41.29 ? 265 TRP A CZ2 1 ATOM 1951 C CZ3 . TRP A 1 265 ? -115.935 19.856 303.947 1.00 36.06 ? 265 TRP A CZ3 1 ATOM 1952 C CH2 . TRP A 1 265 ? -116.262 19.584 305.281 1.00 37.04 ? 265 TRP A CH2 1 ATOM 1953 N N . THR A 1 266 ? -109.173 20.599 303.953 1.00 22.28 ? 266 THR A N 1 ATOM 1954 C CA . THR A 1 266 ? -108.478 21.126 305.120 1.00 26.95 ? 266 THR A CA 1 ATOM 1955 C C . THR A 1 266 ? -107.777 22.452 304.853 1.00 32.90 ? 266 THR A C 1 ATOM 1956 O O . THR A 1 266 ? -107.622 23.256 305.778 1.00 31.96 ? 266 THR A O 1 ATOM 1957 C CB . THR A 1 266 ? -107.454 20.107 305.628 1.00 26.98 ? 266 THR A CB 1 ATOM 1958 O OG1 . THR A 1 266 ? -106.495 19.835 304.599 1.00 24.61 ? 266 THR A OG1 1 ATOM 1959 C CG2 . THR A 1 266 ? -108.144 18.810 306.021 1.00 24.97 ? 266 THR A CG2 1 ATOM 1960 N N . LEU A 1 267 ? -107.358 22.706 303.613 1.00 25.72 ? 267 LEU A N 1 ATOM 1961 C CA . LEU A 1 267 ? -106.559 23.878 303.282 1.00 20.61 ? 267 LEU A CA 1 ATOM 1962 C C . LEU A 1 267 ? -107.392 25.022 302.712 1.00 24.68 ? 267 LEU A C 1 ATOM 1963 O O . LEU A 1 267 ? -106.844 25.898 302.035 1.00 35.10 ? 267 LEU A O 1 ATOM 1964 C CB . LEU A 1 267 ? -105.454 23.495 302.297 1.00 20.05 ? 267 LEU A CB 1 ATOM 1965 C CG . LEU A 1 267 ? -104.384 22.518 302.785 1.00 23.08 ? 267 LEU A CG 1 ATOM 1966 C CD1 . LEU A 1 267 ? -103.585 21.982 301.611 1.00 30.98 ? 267 LEU A CD1 1 ATOM 1967 C CD2 . LEU A 1 267 ? -103.467 23.194 303.782 1.00 25.62 ? 267 LEU A CD2 1 ATOM 1968 N N . SER A 1 268 ? -108.698 25.039 302.972 1.00 22.41 ? 268 SER A N 1 ATOM 1969 C CA . SER A 1 268 ? -109.568 26.079 302.439 1.00 22.33 ? 268 SER A CA 1 ATOM 1970 C C . SER A 1 268 ? -109.720 27.276 303.367 1.00 24.55 ? 268 SER A C 1 ATOM 1971 O O . SER A 1 268 ? -110.305 28.283 302.957 1.00 27.79 ? 268 SER A O 1 ATOM 1972 C CB . SER A 1 268 ? -110.956 25.506 302.132 1.00 24.37 ? 268 SER A CB 1 ATOM 1973 O OG . SER A 1 268 ? -110.893 24.543 301.097 1.00 25.79 ? 268 SER A OG 1 ATOM 1974 N N . ASP A 1 269 ? -109.206 27.194 304.593 1.00 25.46 ? 269 ASP A N 1 ATOM 1975 C CA . ASP A 1 269 ? -109.419 28.270 305.559 1.00 27.93 ? 269 ASP A CA 1 ATOM 1976 C C . ASP A 1 269 ? -108.864 29.624 305.121 1.00 24.32 ? 269 ASP A C 1 ATOM 1977 O O . ASP A 1 269 ? -109.563 30.632 305.326 1.00 36.52 ? 269 ASP A O 1 ATOM 1978 C CB . ASP A 1 269 ? -108.838 27.860 306.918 1.00 29.28 ? 269 ASP A CB 1 ATOM 1979 C CG . ASP A 1 269 ? -109.726 26.879 307.656 1.00 31.90 ? 269 ASP A CG 1 ATOM 1980 O OD1 . ASP A 1 269 ? -110.465 26.128 306.987 1.00 30.23 ? 269 ASP A OD1 1 ATOM 1981 O OD2 . ASP A 1 269 ? -109.686 26.861 308.904 1.00 31.41 ? 269 ASP A OD2 1 ATOM 1982 N N . PRO A 1 270 ? -107.661 29.740 304.546 1.00 21.27 ? 270 PRO A N 1 ATOM 1983 C CA . PRO A 1 270 ? -107.169 31.076 304.168 1.00 23.22 ? 270 PRO A CA 1 ATOM 1984 C C . PRO A 1 270 ? -107.997 31.763 303.096 1.00 27.68 ? 270 PRO A C 1 ATOM 1985 O O . PRO A 1 270 ? -107.851 32.978 302.912 1.00 31.44 ? 270 PRO A O 1 ATOM 1986 C CB . PRO A 1 270 ? -105.742 30.800 303.675 1.00 21.12 ? 270 PRO A CB 1 ATOM 1987 C CG . PRO A 1 270 ? -105.355 29.535 304.344 1.00 31.00 ? 270 PRO A CG 1 ATOM 1988 C CD . PRO A 1 270 ? -106.610 28.721 304.371 1.00 32.68 ? 270 PRO A CD 1 ATOM 1989 N N . PHE A 1 271 ? -108.855 31.033 302.379 1.00 24.87 ? 271 PHE A N 1 ATOM 1990 C CA . PHE A 1 271 ? -109.696 31.665 301.367 1.00 20.78 ? 271 PHE A CA 1 ATOM 1991 C C . PHE A 1 271 ? -110.673 32.651 301.992 1.00 21.76 ? 271 PHE A C 1 ATOM 1992 O O . PHE A 1 271 ? -110.932 33.721 301.430 1.00 21.74 ? 271 PHE A O 1 ATOM 1993 C CB . PHE A 1 271 ? -110.453 30.602 300.573 1.00 20.19 ? 271 PHE A CB 1 ATOM 1994 C CG . PHE A 1 271 ? -109.628 29.922 299.522 1.00 19.86 ? 271 PHE A CG 1 ATOM 1995 C CD1 . PHE A 1 271 ? -108.822 30.659 298.672 1.00 19.93 ? 271 PHE A CD1 1 ATOM 1996 C CD2 . PHE A 1 271 ? -109.663 28.547 299.380 1.00 18.65 ? 271 PHE A CD2 1 ATOM 1997 C CE1 . PHE A 1 271 ? -108.064 30.035 297.700 1.00 18.23 ? 271 PHE A CE1 1 ATOM 1998 C CE2 . PHE A 1 271 ? -108.907 27.917 298.411 1.00 18.81 ? 271 PHE A CE2 1 ATOM 1999 C CZ . PHE A 1 271 ? -108.107 28.662 297.570 1.00 17.16 ? 271 PHE A CZ 1 ATOM 2000 N N . TYR A 1 272 ? -111.225 32.309 303.159 1.00 26.30 ? 272 TYR A N 1 ATOM 2001 C CA . TYR A 1 272 ? -112.237 33.151 303.789 1.00 23.81 ? 272 TYR A CA 1 ATOM 2002 C C . TYR A 1 272 ? -111.693 34.514 304.193 1.00 23.42 ? 272 TYR A C 1 ATOM 2003 O O . TYR A 1 272 ? -112.479 35.447 304.390 1.00 22.01 ? 272 TYR A O 1 ATOM 2004 C CB . TYR A 1 272 ? -112.819 32.443 305.015 1.00 31.72 ? 272 TYR A CB 1 ATOM 2005 C CG . TYR A 1 272 ? -113.458 31.105 304.715 1.00 24.16 ? 272 TYR A CG 1 ATOM 2006 C CD1 . TYR A 1 272 ? -112.706 29.938 304.718 1.00 23.21 ? 272 TYR A CD1 1 ATOM 2007 C CD2 . TYR A 1 272 ? -114.814 31.008 304.435 1.00 26.85 ? 272 TYR A CD2 1 ATOM 2008 C CE1 . TYR A 1 272 ? -113.285 28.714 304.447 1.00 25.09 ? 272 TYR A CE1 1 ATOM 2009 C CE2 . TYR A 1 272 ? -115.402 29.788 304.163 1.00 25.65 ? 272 TYR A CE2 1 ATOM 2010 C CZ . TYR A 1 272 ? -114.632 28.644 304.170 1.00 26.64 ? 272 TYR A CZ 1 ATOM 2011 O OH . TYR A 1 272 ? -115.211 27.426 303.900 1.00 27.12 ? 272 TYR A OH 1 ATOM 2012 N N . PHE A 1 273 ? -110.375 34.654 304.320 1.00 22.78 ? 273 PHE A N 1 ATOM 2013 C CA . PHE A 1 273 ? -109.767 35.913 304.725 1.00 22.47 ? 273 PHE A CA 1 ATOM 2014 C C . PHE A 1 273 ? -109.393 36.807 303.552 1.00 21.01 ? 273 PHE A C 1 ATOM 2015 O O . PHE A 1 273 ? -108.972 37.947 303.775 1.00 23.15 ? 273 PHE A O 1 ATOM 2016 C CB . PHE A 1 273 ? -108.515 35.652 305.567 1.00 22.13 ? 273 PHE A CB 1 ATOM 2017 C CG . PHE A 1 273 ? -108.785 34.923 306.848 1.00 24.77 ? 273 PHE A CG 1 ATOM 2018 C CD1 . PHE A 1 273 ? -109.273 35.597 307.954 1.00 27.47 ? 273 PHE A CD1 1 ATOM 2019 C CD2 . PHE A 1 273 ? -108.543 33.564 306.950 1.00 24.51 ? 273 PHE A CD2 1 ATOM 2020 C CE1 . PHE A 1 273 ? -109.520 34.930 309.136 1.00 30.62 ? 273 PHE A CE1 1 ATOM 2021 C CE2 . PHE A 1 273 ? -108.787 32.891 308.130 1.00 25.76 ? 273 PHE A CE2 1 ATOM 2022 C CZ . PHE A 1 273 ? -109.277 33.575 309.224 1.00 33.45 ? 273 PHE A CZ 1 ATOM 2023 N N . MET A 1 274 ? -109.532 36.330 302.317 1.00 20.70 ? 274 MET A N 1 ATOM 2024 C CA . MET A 1 274 ? -109.088 37.090 301.156 1.00 19.64 ? 274 MET A CA 1 ATOM 2025 C C . MET A 1 274 ? -110.056 38.195 300.757 1.00 21.20 ? 274 MET A C 1 ATOM 2026 O O . MET A 1 274 ? -109.912 38.766 299.671 1.00 23.77 ? 274 MET A O 1 ATOM 2027 C CB . MET A 1 274 ? -108.837 36.149 299.978 1.00 18.99 ? 274 MET A CB 1 ATOM 2028 C CG . MET A 1 274 ? -107.690 35.190 300.235 1.00 18.68 ? 274 MET A CG 1 ATOM 2029 S SD . MET A 1 274 ? -107.110 34.333 298.765 1.00 13.28 ? 274 MET A SD 1 ATOM 2030 C CE . MET A 1 274 ? -105.963 33.174 299.505 1.00 21.13 ? 274 MET A CE 1 ATOM 2031 N N . HIS A 1 275 ? -111.039 38.507 301.602 1.00 21.90 ? 275 HIS A N 1 ATOM 2032 C CA . HIS A 1 275 ? -111.792 39.740 301.428 1.00 22.90 ? 275 HIS A CA 1 ATOM 2033 C C . HIS A 1 275 ? -110.948 40.958 301.776 1.00 28.33 ? 275 HIS A C 1 ATOM 2034 O O . HIS A 1 275 ? -111.244 42.062 301.308 1.00 32.38 ? 275 HIS A O 1 ATOM 2035 C CB . HIS A 1 275 ? -113.046 39.716 302.301 1.00 20.28 ? 275 HIS A CB 1 ATOM 2036 C CG . HIS A 1 275 ? -112.757 39.534 303.758 1.00 22.07 ? 275 HIS A CG 1 ATOM 2037 N ND1 . HIS A 1 275 ? -112.452 38.308 304.309 1.00 32.63 ? 275 HIS A ND1 1 ATOM 2038 C CD2 . HIS A 1 275 ? -112.711 40.425 304.777 1.00 26.15 ? 275 HIS A CD2 1 ATOM 2039 C CE1 . HIS A 1 275 ? -112.238 38.451 305.604 1.00 25.81 ? 275 HIS A CE1 1 ATOM 2040 N NE2 . HIS A 1 275 ? -112.389 39.726 305.914 1.00 25.27 ? 275 HIS A NE2 1 ATOM 2041 N N . ASP A 1 276 ? -109.900 40.772 302.576 1.00 35.16 ? 276 ASP A N 1 ATOM 2042 C CA . ASP A 1 276 ? -109.097 41.869 303.089 1.00 36.98 ? 276 ASP A CA 1 ATOM 2043 C C . ASP A 1 276 ? -108.223 42.450 301.976 1.00 38.63 ? 276 ASP A C 1 ATOM 2044 O O . ASP A 1 276 ? -108.082 41.865 300.899 1.00 33.12 ? 276 ASP A O 1 ATOM 2045 C CB . ASP A 1 276 ? -108.258 41.385 304.275 1.00 50.82 ? 276 ASP A CB 1 ATOM 2046 C CG . ASP A 1 276 ? -107.591 42.520 305.028 1.00 65.15 ? 276 ASP A CG 1 ATOM 2047 O OD1 . ASP A 1 276 ? -107.863 43.690 304.705 1.00 64.96 ? 276 ASP A OD1 1 ATOM 2048 O OD2 . ASP A 1 276 ? -106.809 42.247 305.960 1.00 69.36 ? 276 ASP A OD2 1 ATOM 2049 N N . VAL A 1 277 ? -107.624 43.615 302.271 1.00 49.38 ? 277 VAL A N 1 ATOM 2050 C CA . VAL A 1 277 ? -106.924 44.505 301.338 1.00 71.35 ? 277 VAL A CA 1 ATOM 2051 C C . VAL A 1 277 ? -106.594 43.852 299.998 1.00 48.38 ? 277 VAL A C 1 ATOM 2052 O O . VAL A 1 277 ? -107.041 44.324 298.945 1.00 45.84 ? 277 VAL A O 1 ATOM 2053 C CB . VAL A 1 277 ? -105.660 45.110 302.003 1.00 104.44 ? 277 VAL A CB 1 ATOM 2054 C CG1 . VAL A 1 277 ? -106.009 45.699 303.344 1.00 81.54 ? 277 VAL A CG1 1 ATOM 2055 C CG2 . VAL A 1 277 ? -104.546 44.085 302.226 1.00 69.28 ? 277 VAL A CG2 1 ATOM 2056 N N . GLU A 1 278 ? -105.867 42.736 300.048 1.00 42.29 ? 278 GLU A N 1 ATOM 2057 C CA . GLU A 1 278 ? -105.355 41.975 298.918 1.00 45.99 ? 278 GLU A CA 1 ATOM 2058 C C . GLU A 1 278 ? -104.192 41.134 299.424 1.00 44.77 ? 278 GLU A C 1 ATOM 2059 O O . GLU A 1 278 ? -103.125 41.088 298.802 1.00 41.77 ? 278 GLU A O 1 ATOM 2060 C CB . GLU A 1 278 ? -104.909 42.857 297.747 1.00 52.23 ? 278 GLU A CB 1 ATOM 2061 C CG . GLU A 1 278 ? -104.829 42.099 296.429 1.00 56.92 ? 278 GLU A CG 1 ATOM 2062 C CD . GLU A 1 278 ? -105.519 42.792 295.273 1.00 94.04 ? 278 GLU A CD 1 ATOM 2063 O OE1 . GLU A 1 278 ? -105.572 44.039 295.265 1.00 106.36 ? 278 GLU A OE1 1 ATOM 2064 O OE2 . GLU A 1 278 ? -105.990 42.084 294.358 1.00 117.96 ? 278 GLU A OE2 1 ATOM 2065 N N . LYS A 1 279 ? -104.379 40.486 300.578 1.00 35.10 ? 279 LYS A N 1 ATOM 2066 C CA . LYS A 1 279 ? -103.640 39.258 300.833 1.00 31.60 ? 279 LYS A CA 1 ATOM 2067 C C . LYS A 1 279 ? -103.837 38.296 299.676 1.00 33.59 ? 279 LYS A C 1 ATOM 2068 O O . LYS A 1 279 ? -103.037 37.373 299.488 1.00 58.55 ? 279 LYS A O 1 ATOM 2069 C CB . LYS A 1 279 ? -104.103 38.621 302.145 1.00 29.75 ? 279 LYS A CB 1 ATOM 2070 C CG . LYS A 1 279 ? -104.415 39.619 303.248 1.00 32.72 ? 279 LYS A CG 1 ATOM 2071 C CD . LYS A 1 279 ? -104.367 38.954 304.609 1.00 29.89 ? 279 LYS A CD 1 ATOM 2072 C CE . LYS A 1 279 ? -105.396 39.545 305.550 1.00 32.76 ? 279 LYS A CE 1 ATOM 2073 N NZ . LYS A 1 279 ? -105.388 38.902 306.890 1.00 28.62 ? 279 LYS A NZ 1 ATOM 2074 N N . ARG A 1 280 ? -104.920 38.496 298.923 1.00 28.54 ? 280 ARG A N 1 ATOM 2075 C CA . ARG A 1 280 ? -105.085 37.932 297.591 1.00 35.65 ? 280 ARG A CA 1 ATOM 2076 C C . ARG A 1 280 ? -103.840 38.135 296.731 1.00 49.68 ? 280 ARG A C 1 ATOM 2077 O O . ARG A 1 280 ? -103.396 37.211 296.045 1.00 43.30 ? 280 ARG A O 1 ATOM 2078 C CB . ARG A 1 280 ? -106.310 38.584 296.950 1.00 33.73 ? 280 ARG A CB 1 ATOM 2079 C CG . ARG A 1 280 ? -107.005 37.802 295.870 1.00 42.70 ? 280 ARG A CG 1 ATOM 2080 C CD . ARG A 1 280 ? -108.487 38.146 295.902 1.00 31.84 ? 280 ARG A CD 1 ATOM 2081 N NE . ARG A 1 280 ? -108.729 39.555 295.588 1.00 31.48 ? 280 ARG A NE 1 ATOM 2082 C CZ . ARG A 1 280 ? -109.248 40.433 296.442 1.00 32.33 ? 280 ARG A CZ 1 ATOM 2083 N NH1 . ARG A 1 280 ? -109.585 40.052 297.668 1.00 28.63 ? 280 ARG A NH1 1 ATOM 2084 N NH2 . ARG A 1 280 ? -109.435 41.692 296.071 1.00 31.46 ? 280 ARG A NH2 1 ATOM 2085 N N . ASN A 1 281 ? -103.266 39.345 296.736 1.00 42.22 ? 281 ASN A N 1 ATOM 2086 C CA . ASN A 1 281 ? -102.017 39.553 296.001 1.00 46.14 ? 281 ASN A CA 1 ATOM 2087 C C . ASN A 1 281 ? -100.886 38.739 296.611 1.00 36.12 ? 281 ASN A C 1 ATOM 2088 O O . ASN A 1 281 ? -100.121 38.088 295.892 1.00 36.90 ? 281 ASN A O 1 ATOM 2089 C CB . ASN A 1 281 ? -101.639 41.035 295.958 1.00 55.55 ? 281 ASN A CB 1 ATOM 2090 C CG . ASN A 1 281 ? -101.991 41.684 294.635 1.00 71.44 ? 281 ASN A CG 1 ATOM 2091 O OD1 . ASN A 1 281 ? -102.048 41.018 293.602 1.00 107.89 ? 281 ASN A OD1 1 ATOM 2092 N ND2 . ASN A 1 281 ? -102.207 42.994 294.655 1.00 71.91 ? 281 ASN A ND2 1 ATOM 2093 N N . VAL A 1 282 ? -100.764 38.766 297.941 1.00 31.70 ? 282 VAL A N 1 ATOM 2094 C CA . VAL A 1 282 ? -99.856 37.850 298.624 1.00 30.09 ? 282 VAL A CA 1 ATOM 2095 C C . VAL A 1 282 ? -100.125 36.422 298.175 1.00 45.51 ? 282 VAL A C 1 ATOM 2096 O O . VAL A 1 282 ? -99.202 35.604 298.068 1.00 70.02 ? 282 VAL A O 1 ATOM 2097 C CB . VAL A 1 282 ? -100.000 38.009 300.152 1.00 28.93 ? 282 VAL A CB 1 ATOM 2098 C CG1 . VAL A 1 282 ? -98.999 37.145 300.885 1.00 33.59 ? 282 VAL A CG1 1 ATOM 2099 C CG2 . VAL A 1 282 ? -99.852 39.473 300.550 1.00 32.99 ? 282 VAL A CG2 1 ATOM 2100 N N . PHE A 1 283 ? -101.387 36.108 297.882 1.00 29.62 ? 283 PHE A N 1 ATOM 2101 C CA . PHE A 1 283 ? -101.749 34.827 297.288 1.00 27.74 ? 283 PHE A CA 1 ATOM 2102 C C . PHE A 1 283 ? -101.452 34.801 295.790 1.00 28.98 ? 283 PHE A C 1 ATOM 2103 O O . PHE A 1 283 ? -100.693 33.951 295.315 1.00 33.15 ? 283 PHE A O 1 ATOM 2104 C CB . PHE A 1 283 ? -103.229 34.540 297.558 1.00 26.19 ? 283 PHE A CB 1 ATOM 2105 C CG . PHE A 1 283 ? -103.795 33.416 296.742 1.00 26.48 ? 283 PHE A CG 1 ATOM 2106 C CD1 . PHE A 1 283 ? -103.494 32.100 297.038 1.00 24.92 ? 283 PHE A CD1 1 ATOM 2107 C CD2 . PHE A 1 283 ? -104.640 33.683 295.678 1.00 26.31 ? 283 PHE A CD2 1 ATOM 2108 C CE1 . PHE A 1 283 ? -104.024 31.069 296.284 1.00 23.19 ? 283 PHE A CE1 1 ATOM 2109 C CE2 . PHE A 1 283 ? -105.170 32.658 294.922 1.00 24.28 ? 283 PHE A CE2 1 ATOM 2110 C CZ . PHE A 1 283 ? -104.862 31.350 295.225 1.00 24.66 ? 283 PHE A CZ 1 ATOM 2111 N N . VAL A 1 284 ? -102.031 35.740 295.035 1.00 29.47 ? 284 VAL A N 1 ATOM 2112 C CA . VAL A 1 284 ? -101.939 35.696 293.574 1.00 28.27 ? 284 VAL A CA 1 ATOM 2113 C C . VAL A 1 284 ? -100.492 35.839 293.116 1.00 30.52 ? 284 VAL A C 1 ATOM 2114 O O . VAL A 1 284 ? -100.014 35.070 292.273 1.00 33.33 ? 284 VAL A O 1 ATOM 2115 C CB . VAL A 1 284 ? -102.838 36.774 292.941 1.00 28.45 ? 284 VAL A CB 1 ATOM 2116 C CG1 . VAL A 1 284 ? -102.588 36.858 291.447 1.00 28.75 ? 284 VAL A CG1 1 ATOM 2117 C CG2 . VAL A 1 284 ? -104.304 36.469 293.205 1.00 27.60 ? 284 VAL A CG2 1 ATOM 2118 N N . ASP A 1 285 ? -99.775 36.833 293.651 1.00 33.12 ? 285 ASP A N 1 ATOM 2119 C CA . ASP A 1 285 ? -98.378 37.011 293.261 1.00 32.34 ? 285 ASP A CA 1 ATOM 2120 C C . ASP A 1 285 ? -97.547 35.782 293.599 1.00 32.04 ? 285 ASP A C 1 ATOM 2121 O O . ASP A 1 285 ? -96.578 35.475 292.895 1.00 54.02 ? 285 ASP A O 1 ATOM 2122 C CB . ASP A 1 285 ? -97.786 38.251 293.931 1.00 37.17 ? 285 ASP A CB 1 ATOM 2123 C CG . ASP A 1 285 ? -98.554 39.514 293.600 1.00 43.45 ? 285 ASP A CG 1 ATOM 2124 O OD1 . ASP A 1 285 ? -99.610 39.413 292.942 1.00 43.51 ? 285 ASP A OD1 1 ATOM 2125 O OD2 . ASP A 1 285 ? -98.100 40.608 293.996 1.00 72.47 ? 285 ASP A OD2 1 ATOM 2126 N N . SER A 1 286 ? -97.908 35.067 294.666 1.00 28.06 ? 286 SER A N 1 ATOM 2127 C CA . SER A 1 286 ? -97.246 33.800 294.952 1.00 30.54 ? 286 SER A CA 1 ATOM 2128 C C . SER A 1 286 ? -97.668 32.728 293.956 1.00 26.61 ? 286 SER A C 1 ATOM 2129 O O . SER A 1 286 ? -96.852 31.889 293.558 1.00 26.80 ? 286 SER A O 1 ATOM 2130 C CB . SER A 1 286 ? -97.548 33.359 296.384 1.00 30.46 ? 286 SER A CB 1 ATOM 2131 O OG . SER A 1 286 ? -98.933 33.130 296.565 1.00 28.31 ? 286 SER A OG 1 ATOM 2132 N N . VAL A 1 287 ? -98.938 32.741 293.540 1.00 26.71 ? 287 VAL A N 1 ATOM 2133 C CA . VAL A 1 287 ? -99.387 31.818 292.501 1.00 26.16 ? 287 VAL A CA 1 ATOM 2134 C C . VAL A 1 287 ? -98.656 32.093 291.195 1.00 26.24 ? 287 VAL A C 1 ATOM 2135 O O . VAL A 1 287 ? -98.298 31.166 290.459 1.00 49.78 ? 287 VAL A O 1 ATOM 2136 C CB . VAL A 1 287 ? -100.915 31.907 292.320 1.00 23.48 ? 287 VAL A CB 1 ATOM 2137 C CG1 . VAL A 1 287 ? -101.371 30.995 291.194 1.00 18.63 ? 287 VAL A CG1 1 ATOM 2138 C CG2 . VAL A 1 287 ? -101.628 31.532 293.603 1.00 23.31 ? 287 VAL A CG2 1 ATOM 2139 N N . LYS A 1 288 ? -98.412 33.370 290.890 1.00 25.86 ? 288 LYS A N 1 ATOM 2140 C CA . LYS A 1 288 ? -97.760 33.703 289.628 1.00 26.82 ? 288 LYS A CA 1 ATOM 2141 C C . LYS A 1 288 ? -96.298 33.276 289.621 1.00 29.19 ? 288 LYS A C 1 ATOM 2142 O O . LYS A 1 288 ? -95.765 32.925 288.563 1.00 35.60 ? 288 LYS A O 1 ATOM 2143 C CB . LYS A 1 288 ? -97.892 35.201 289.341 1.00 34.70 ? 288 LYS A CB 1 ATOM 2144 C CG . LYS A 1 288 ? -96.595 35.990 289.411 1.00 41.52 ? 288 LYS A CG 1 ATOM 2145 C CD . LYS A 1 288 ? -96.729 37.318 288.683 1.00 64.84 ? 288 LYS A CD 1 ATOM 2146 C CE . LYS A 1 288 ? -95.369 37.905 288.344 1.00 93.63 ? 288 LYS A CE 1 ATOM 2147 N NZ . LYS A 1 288 ? -95.485 39.087 287.446 1.00 93.11 ? 288 LYS A NZ 1 ATOM 2148 N N . GLU A 1 289 ? -95.637 33.288 290.781 1.00 28.64 ? 289 GLU A N 1 ATOM 2149 C CA . GLU A 1 289 ? -94.279 32.764 290.850 1.00 28.67 ? 289 GLU A CA 1 ATOM 2150 C C . GLU A 1 289 ? -94.270 31.247 290.969 1.00 24.53 ? 289 GLU A C 1 ATOM 2151 O O . GLU A 1 289 ? -93.369 30.593 290.435 1.00 24.30 ? 289 GLU A O 1 ATOM 2152 C CB . GLU A 1 289 ? -93.519 33.394 292.020 1.00 38.75 ? 289 GLU A CB 1 ATOM 2153 C CG . GLU A 1 289 ? -92.093 32.875 292.174 1.00 49.80 ? 289 GLU A CG 1 ATOM 2154 C CD . GLU A 1 289 ? -91.116 33.948 292.611 1.00 46.53 ? 289 GLU A CD 1 ATOM 2155 O OE1 . GLU A 1 289 ? -91.404 34.652 293.600 1.00 70.23 ? 289 GLU A OE1 1 ATOM 2156 O OE2 . GLU A 1 289 ? -90.055 34.084 291.964 1.00 44.36 ? 289 GLU A OE2 1 ATOM 2157 N N . PHE A 1 290 ? -95.268 30.676 291.648 1.00 23.10 ? 290 PHE A N 1 ATOM 2158 C CA . PHE A 1 290 ? -95.372 29.225 291.745 1.00 24.42 ? 290 PHE A CA 1 ATOM 2159 C C . PHE A 1 290 ? -95.477 28.575 290.372 1.00 24.59 ? 290 PHE A C 1 ATOM 2160 O O . PHE A 1 290 ? -94.992 27.456 290.176 1.00 38.76 ? 290 PHE A O 1 ATOM 2161 C CB . PHE A 1 290 ? -96.580 28.851 292.606 1.00 23.46 ? 290 PHE A CB 1 ATOM 2162 C CG . PHE A 1 290 ? -96.611 27.409 293.024 1.00 23.79 ? 290 PHE A CG 1 ATOM 2163 C CD1 . PHE A 1 290 ? -97.189 26.449 292.210 1.00 24.58 ? 290 PHE A CD1 1 ATOM 2164 C CD2 . PHE A 1 290 ? -96.071 27.015 294.236 1.00 24.30 ? 290 PHE A CD2 1 ATOM 2165 C CE1 . PHE A 1 290 ? -97.221 25.124 292.594 1.00 21.90 ? 290 PHE A CE1 1 ATOM 2166 C CE2 . PHE A 1 290 ? -96.101 25.691 294.625 1.00 23.76 ? 290 PHE A CE2 1 ATOM 2167 C CZ . PHE A 1 290 ? -96.676 24.744 293.803 1.00 23.35 ? 290 PHE A CZ 1 ATOM 2168 N N . LEU A 1 291 ? -96.096 29.259 289.410 1.00 21.44 ? 291 LEU A N 1 ATOM 2169 C CA . LEU A 1 291 ? -96.300 28.691 288.085 1.00 21.60 ? 291 LEU A CA 1 ATOM 2170 C C . LEU A 1 291 ? -95.122 28.909 287.147 1.00 21.51 ? 291 LEU A C 1 ATOM 2171 O O . LEU A 1 291 ? -94.977 28.157 286.177 1.00 28.63 ? 291 LEU A O 1 ATOM 2172 C CB . LEU A 1 291 ? -97.567 29.269 287.452 1.00 22.69 ? 291 LEU A CB 1 ATOM 2173 C CG . LEU A 1 291 ? -98.868 28.893 288.162 1.00 20.22 ? 291 LEU A CG 1 ATOM 2174 C CD1 . LEU A 1 291 ? -100.061 29.406 287.382 1.00 21.93 ? 291 LEU A CD1 1 ATOM 2175 C CD2 . LEU A 1 291 ? -98.958 27.388 288.366 1.00 19.35 ? 291 LEU A CD2 1 ATOM 2176 N N . GLN A 1 292 ? -94.286 29.917 287.396 1.00 23.53 ? 292 GLN A N 1 ATOM 2177 C CA . GLN A 1 292 ? -93.063 30.076 286.620 1.00 24.40 ? 292 GLN A CA 1 ATOM 2178 C C . GLN A 1 292 ? -91.863 29.414 287.279 1.00 18.62 ? 292 GLN A C 1 ATOM 2179 O O . GLN A 1 292 ? -90.881 29.117 286.590 1.00 19.31 ? 292 GLN A O 1 ATOM 2180 C CB . GLN A 1 292 ? -92.767 31.559 286.372 1.00 29.32 ? 292 GLN A CB 1 ATOM 2181 C CG . GLN A 1 292 ? -92.759 32.424 287.613 1.00 41.22 ? 292 GLN A CG 1 ATOM 2182 C CD . GLN A 1 292 ? -92.976 33.890 287.293 1.00 30.10 ? 292 GLN A CD 1 ATOM 2183 O OE1 . GLN A 1 292 ? -93.089 34.272 286.128 1.00 25.39 ? 292 GLN A OE1 1 ATOM 2184 N NE2 . GLN A 1 292 ? -93.039 34.720 288.328 1.00 41.98 ? 292 GLN A NE2 1 ATOM 2185 N N . VAL A 1 293 ? -91.916 29.180 288.591 1.00 18.97 ? 293 VAL A N 1 ATOM 2186 C CA . VAL A 1 293 ? -90.928 28.312 289.224 1.00 21.29 ? 293 VAL A CA 1 ATOM 2187 C C . VAL A 1 293 ? -91.161 26.867 288.805 1.00 20.52 ? 293 VAL A C 1 ATOM 2188 O O . VAL A 1 293 ? -90.244 26.183 288.337 1.00 24.29 ? 293 VAL A O 1 ATOM 2189 C CB . VAL A 1 293 ? -90.969 28.471 290.754 1.00 20.66 ? 293 VAL A CB 1 ATOM 2190 C CG1 . VAL A 1 293 ? -90.256 27.309 291.426 1.00 19.37 ? 293 VAL A CG1 1 ATOM 2191 C CG2 . VAL A 1 293 ? -90.338 29.790 291.165 1.00 24.53 ? 293 VAL A CG2 1 ATOM 2192 N N . TRP A 1 294 ? -92.394 26.388 288.954 1.00 19.42 ? 294 TRP A N 1 ATOM 2193 C CA . TRP A 1 294 ? -92.787 25.048 288.527 1.00 19.55 ? 294 TRP A CA 1 ATOM 2194 C C . TRP A 1 294 ? -93.524 25.189 287.200 1.00 16.55 ? 294 TRP A C 1 ATOM 2195 O O . TRP A 1 294 ? -94.721 25.485 287.171 1.00 17.93 ? 294 TRP A O 1 ATOM 2196 C CB . TRP A 1 294 ? -93.656 24.373 289.582 1.00 18.67 ? 294 TRP A CB 1 ATOM 2197 C CG . TRP A 1 294 ? -93.097 24.467 290.964 1.00 21.00 ? 294 TRP A CG 1 ATOM 2198 C CD1 . TRP A 1 294 ? -93.494 25.320 291.952 1.00 23.16 ? 294 TRP A CD1 1 ATOM 2199 C CD2 . TRP A 1 294 ? -92.034 23.682 291.515 1.00 19.87 ? 294 TRP A CD2 1 ATOM 2200 N NE1 . TRP A 1 294 ? -92.747 25.113 293.085 1.00 26.24 ? 294 TRP A NE1 1 ATOM 2201 C CE2 . TRP A 1 294 ? -91.842 24.113 292.843 1.00 20.21 ? 294 TRP A CE2 1 ATOM 2202 C CE3 . TRP A 1 294 ? -91.226 22.657 291.016 1.00 21.34 ? 294 TRP A CE3 1 ATOM 2203 C CZ2 . TRP A 1 294 ? -90.877 23.554 293.677 1.00 19.30 ? 294 TRP A CZ2 1 ATOM 2204 C CZ3 . TRP A 1 294 ? -90.268 22.104 291.846 1.00 21.66 ? 294 TRP A CZ3 1 ATOM 2205 C CH2 . TRP A 1 294 ? -90.102 22.553 293.161 1.00 21.08 ? 294 TRP A CH2 1 ATOM 2206 N N . LYS A 1 295 ? -92.805 24.976 286.098 1.00 18.42 ? 295 LYS A N 1 ATOM 2207 C CA . LYS A 1 295 ? -93.376 25.198 284.776 1.00 17.89 ? 295 LYS A CA 1 ATOM 2208 C C . LYS A 1 295 ? -94.230 24.035 284.289 1.00 19.58 ? 295 LYS A C 1 ATOM 2209 O O . LYS A 1 295 ? -95.014 24.216 283.351 1.00 21.42 ? 295 LYS A O 1 ATOM 2210 C CB . LYS A 1 295 ? -92.263 25.476 283.764 1.00 18.33 ? 295 LYS A CB 1 ATOM 2211 C CG . LYS A 1 295 ? -91.416 26.688 284.106 1.00 20.47 ? 295 LYS A CG 1 ATOM 2212 C CD . LYS A 1 295 ? -90.259 26.852 283.137 1.00 24.69 ? 295 LYS A CD 1 ATOM 2213 C CE . LYS A 1 295 ? -89.409 28.058 283.502 1.00 32.18 ? 295 LYS A CE 1 ATOM 2214 N NZ . LYS A 1 295 ? -88.178 28.143 282.669 1.00 72.80 ? 295 LYS A NZ 1 ATOM 2215 N N . PHE A 1 296 ? -94.106 22.854 284.898 1.00 19.52 ? 296 PHE A N 1 ATOM 2216 C CA . PHE A 1 296 ? -94.878 21.703 284.445 1.00 21.19 ? 296 PHE A CA 1 ATOM 2217 C C . PHE A 1 296 ? -96.366 21.829 284.745 1.00 20.78 ? 296 PHE A C 1 ATOM 2218 O O . PHE A 1 296 ? -97.155 21.053 284.196 1.00 37.84 ? 296 PHE A O 1 ATOM 2219 C CB . PHE A 1 296 ? -94.321 20.417 285.062 1.00 22.15 ? 296 PHE A CB 1 ATOM 2220 C CG . PHE A 1 296 ? -94.383 20.381 286.562 1.00 22.40 ? 296 PHE A CG 1 ATOM 2221 C CD1 . PHE A 1 296 ? -93.342 20.887 287.321 1.00 22.12 ? 296 PHE A CD1 1 ATOM 2222 C CD2 . PHE A 1 296 ? -95.471 19.825 287.212 1.00 20.11 ? 296 PHE A CD2 1 ATOM 2223 C CE1 . PHE A 1 296 ? -93.392 20.852 288.700 1.00 19.54 ? 296 PHE A CE1 1 ATOM 2224 C CE2 . PHE A 1 296 ? -95.525 19.787 288.590 1.00 19.67 ? 296 PHE A CE2 1 ATOM 2225 C CZ . PHE A 1 296 ? -94.485 20.302 289.334 1.00 17.50 ? 296 PHE A CZ 1 ATOM 2226 N N . PHE A 1 297 ? -96.768 22.771 285.594 1.00 17.37 ? 297 PHE A N 1 ATOM 2227 C CA . PHE A 1 297 ? -98.180 23.062 285.779 1.00 17.10 ? 297 PHE A CA 1 ATOM 2228 C C . PHE A 1 297 ? -98.704 23.880 284.604 1.00 17.90 ? 297 PHE A C 1 ATOM 2229 O O . PHE A 1 297 ? -97.959 24.617 283.952 1.00 19.82 ? 297 PHE A O 1 ATOM 2230 C CB . PHE A 1 297 ? -98.414 23.816 287.087 1.00 16.28 ? 297 PHE A CB 1 ATOM 2231 C CG . PHE A 1 297 ? -98.170 22.989 288.315 1.00 14.49 ? 297 PHE A CG 1 ATOM 2232 C CD1 . PHE A 1 297 ? -98.942 21.870 288.575 1.00 15.41 ? 297 PHE A CD1 1 ATOM 2233 C CD2 . PHE A 1 297 ? -97.177 23.334 289.215 1.00 16.93 ? 297 PHE A CD2 1 ATOM 2234 C CE1 . PHE A 1 297 ? -98.725 21.108 289.706 1.00 17.98 ? 297 PHE A CE1 1 ATOM 2235 C CE2 . PHE A 1 297 ? -96.955 22.575 290.347 1.00 17.90 ? 297 PHE A CE2 1 ATOM 2236 C CZ . PHE A 1 297 ? -97.731 21.462 290.594 1.00 17.15 ? 297 PHE A CZ 1 ATOM 2237 N N . ASP A 1 298 ? -100.004 23.745 284.336 1.00 18.29 ? 298 ASP A N 1 ATOM 2238 C CA . ASP A 1 298 ? -100.621 24.386 283.181 1.00 22.14 ? 298 ASP A CA 1 ATOM 2239 C C . ASP A 1 298 ? -101.758 25.325 283.569 1.00 23.47 ? 298 ASP A C 1 ATOM 2240 O O . ASP A 1 298 ? -102.602 25.646 282.726 1.00 26.81 ? 298 ASP A O 1 ATOM 2241 C CB . ASP A 1 298 ? -101.122 23.332 282.192 1.00 25.21 ? 298 ASP A CB 1 ATOM 2242 C CG . ASP A 1 298 ? -100.010 22.436 281.686 1.00 31.23 ? 298 ASP A CG 1 ATOM 2243 O OD1 . ASP A 1 298 ? -99.168 22.919 280.900 1.00 38.95 ? 298 ASP A OD1 1 ATOM 2244 O OD2 . ASP A 1 298 ? -99.979 21.250 282.073 1.00 21.97 ? 298 ASP A OD2 1 ATOM 2245 N N . GLY A 1 299 ? -101.803 25.775 284.814 1.00 24.71 ? 299 GLY A N 1 ATOM 2246 C CA . GLY A 1 299 ? -102.842 26.716 285.204 1.00 23.52 ? 299 GLY A CA 1 ATOM 2247 C C . GLY A 1 299 ? -103.007 26.759 286.715 1.00 19.30 ? 299 GLY A C 1 ATOM 2248 O O . GLY A 1 299 ? -102.047 26.571 287.461 1.00 20.83 ? 299 GLY A O 1 ATOM 2249 N N . VAL A 1 300 ? -104.240 27.041 287.136 1.00 15.66 ? 300 VAL A N 1 ATOM 2250 C CA . VAL A 1 300 ? -104.603 27.125 288.548 1.00 15.03 ? 300 VAL A CA 1 ATOM 2251 C C . VAL A 1 300 ? -105.941 26.429 288.748 1.00 21.15 ? 300 VAL A C 1 ATOM 2252 O O . VAL A 1 300 ? -106.827 26.504 287.890 1.00 22.64 ? 300 VAL A O 1 ATOM 2253 C CB . VAL A 1 300 ? -104.689 28.586 289.046 1.00 14.91 ? 300 VAL A CB 1 ATOM 2254 C CG1 . VAL A 1 300 ? -104.796 28.627 290.562 1.00 16.10 ? 300 VAL A CG1 1 ATOM 2255 C CG2 . VAL A 1 300 ? -103.496 29.401 288.581 1.00 17.98 ? 300 VAL A CG2 1 ATOM 2256 N N . ASP A 1 301 ? -106.089 25.753 289.886 1.00 21.59 ? 301 ASP A N 1 ATOM 2257 C CA . ASP A 1 301 ? -107.358 25.162 290.295 1.00 21.87 ? 301 ASP A CA 1 ATOM 2258 C C . ASP A 1 301 ? -107.686 25.656 291.695 1.00 21.62 ? 301 ASP A C 1 ATOM 2259 O O . ASP A 1 301 ? -106.919 25.418 292.634 1.00 26.50 ? 301 ASP A O 1 ATOM 2260 C CB . ASP A 1 301 ? -107.300 23.633 290.263 1.00 22.28 ? 301 ASP A CB 1 ATOM 2261 C CG . ASP A 1 301 ? -108.634 22.995 290.597 1.00 24.98 ? 301 ASP A CG 1 ATOM 2262 O OD1 . ASP A 1 301 ? -109.677 23.552 290.195 1.00 21.89 ? 301 ASP A OD1 1 ATOM 2263 O OD2 . ASP A 1 301 ? -108.640 21.936 291.260 1.00 25.44 ? 301 ASP A OD2 1 ATOM 2264 N N . VAL A 1 302 ? -108.816 26.340 291.834 1.00 20.96 ? 302 VAL A N 1 ATOM 2265 C CA . VAL A 1 302 ? -109.230 26.937 293.098 1.00 18.39 ? 302 VAL A CA 1 ATOM 2266 C C . VAL A 1 302 ? -110.264 26.017 293.733 1.00 17.10 ? 302 VAL A C 1 ATOM 2267 O O . VAL A 1 302 ? -111.381 25.877 293.227 1.00 17.30 ? 302 VAL A O 1 ATOM 2268 C CB . VAL A 1 302 ? -109.792 28.350 292.898 1.00 21.01 ? 302 VAL A CB 1 ATOM 2269 C CG1 . VAL A 1 302 ? -110.170 28.964 294.237 1.00 18.63 ? 302 VAL A CG1 1 ATOM 2270 C CG2 . VAL A 1 302 ? -108.783 29.218 292.170 1.00 22.43 ? 302 VAL A CG2 1 ATOM 2271 N N . ASP A 1 303 ? -109.901 25.398 294.851 1.00 15.69 ? 303 ASP A N 1 ATOM 2272 C CA . ASP A 1 303 ? -110.775 24.466 295.550 1.00 15.22 ? 303 ASP A CA 1 ATOM 2273 C C . ASP A 1 303 ? -111.190 25.069 296.889 1.00 16.31 ? 303 ASP A C 1 ATOM 2274 O O . ASP A 1 303 ? -110.827 24.581 297.961 1.00 22.88 ? 303 ASP A O 1 ATOM 2275 C CB . ASP A 1 303 ? -110.070 23.120 295.733 1.00 16.59 ? 303 ASP A CB 1 ATOM 2276 C CG . ASP A 1 303 ? -109.634 22.510 294.417 1.00 18.68 ? 303 ASP A CG 1 ATOM 2277 O OD1 . ASP A 1 303 ? -110.362 21.647 293.887 1.00 20.27 ? 303 ASP A OD1 1 ATOM 2278 O OD2 . ASP A 1 303 ? -108.563 22.900 293.908 1.00 27.97 ? 303 ASP A OD2 1 ATOM 2279 N N . TRP A 1 304 ? -111.965 26.149 296.819 1.00 17.36 ? 304 TRP A N 1 ATOM 2280 C CA . TRP A 1 304 ? -112.485 26.786 298.022 1.00 19.04 ? 304 TRP A CA 1 ATOM 2281 C C . TRP A 1 304 ? -113.665 25.974 298.540 1.00 19.73 ? 304 TRP A C 1 ATOM 2282 O O . TRP A 1 304 ? -114.683 25.838 297.852 1.00 19.35 ? 304 TRP A O 1 ATOM 2283 C CB . TRP A 1 304 ? -112.899 28.228 297.737 1.00 18.13 ? 304 TRP A CB 1 ATOM 2284 C CG . TRP A 1 304 ? -113.278 29.015 298.967 1.00 19.88 ? 304 TRP A CG 1 ATOM 2285 C CD1 . TRP A 1 304 ? -113.353 28.552 300.251 1.00 21.80 ? 304 TRP A CD1 1 ATOM 2286 C CD2 . TRP A 1 304 ? -113.627 30.403 299.024 1.00 23.70 ? 304 TRP A CD2 1 ATOM 2287 N NE1 . TRP A 1 304 ? -113.730 29.563 301.099 1.00 23.00 ? 304 TRP A NE1 1 ATOM 2288 C CE2 . TRP A 1 304 ? -113.904 30.710 300.371 1.00 24.06 ? 304 TRP A CE2 1 ATOM 2289 C CE3 . TRP A 1 304 ? -113.733 31.417 298.067 1.00 24.74 ? 304 TRP A CE3 1 ATOM 2290 C CZ2 . TRP A 1 304 ? -114.278 31.986 300.784 1.00 25.12 ? 304 TRP A CZ2 1 ATOM 2291 C CZ3 . TRP A 1 304 ? -114.106 32.683 298.479 1.00 23.75 ? 304 TRP A CZ3 1 ATOM 2292 C CH2 . TRP A 1 304 ? -114.373 32.956 299.825 1.00 25.92 ? 304 TRP A CH2 1 ATOM 2293 N N . GLU A 1 305 ? -113.529 25.439 299.748 1.00 20.14 ? 305 GLU A N 1 ATOM 2294 C CA . GLU A 1 305 ? -114.567 24.606 300.341 1.00 24.27 ? 305 GLU A CA 1 ATOM 2295 C C . GLU A 1 305 ? -114.958 25.101 301.731 1.00 28.11 ? 305 GLU A C 1 ATOM 2296 O O . GLU A 1 305 ? -114.290 24.776 302.712 1.00 27.65 ? 305 GLU A O 1 ATOM 2297 C CB . GLU A 1 305 ? -114.100 23.151 300.429 1.00 22.15 ? 305 GLU A CB 1 ATOM 2298 C CG . GLU A 1 305 ? -113.775 22.510 299.091 1.00 25.11 ? 305 GLU A CG 1 ATOM 2299 C CD . GLU A 1 305 ? -113.351 21.061 299.232 1.00 21.98 ? 305 GLU A CD 1 ATOM 2300 O OE1 . GLU A 1 305 ? -113.596 20.471 300.305 1.00 21.99 ? 305 GLU A OE1 1 ATOM 2301 O OE2 . GLU A 1 305 ? -112.771 20.513 298.271 1.00 37.37 ? 305 GLU A OE2 1 ATOM 2302 N N . PHE A 1 306 ? -116.031 25.883 301.825 1.00 26.20 ? 306 PHE A N 1 ATOM 2303 C CA . PHE A 1 306 ? -116.810 26.333 300.674 1.00 26.66 ? 306 PHE A CA 1 ATOM 2304 C C . PHE A 1 306 ? -117.106 27.823 300.827 1.00 30.36 ? 306 PHE A C 1 ATOM 2305 O O . PHE A 1 306 ? -117.111 28.339 301.944 1.00 45.34 ? 306 PHE A O 1 ATOM 2306 C CB . PHE A 1 306 ? -118.119 25.543 300.549 1.00 28.97 ? 306 PHE A CB 1 ATOM 2307 C CG . PHE A 1 306 ? -117.932 24.054 300.511 1.00 25.06 ? 306 PHE A CG 1 ATOM 2308 C CD1 . PHE A 1 306 ? -117.698 23.404 299.311 1.00 20.68 ? 306 PHE A CD1 1 ATOM 2309 C CD2 . PHE A 1 306 ? -117.999 23.304 301.672 1.00 27.13 ? 306 PHE A CD2 1 ATOM 2310 C CE1 . PHE A 1 306 ? -117.525 22.035 299.272 1.00 24.00 ? 306 PHE A CE1 1 ATOM 2311 C CE2 . PHE A 1 306 ? -117.829 21.934 301.639 1.00 26.78 ? 306 PHE A CE2 1 ATOM 2312 C CZ . PHE A 1 306 ? -117.593 21.299 300.437 1.00 28.20 ? 306 PHE A CZ 1 ATOM 2313 N N . PRO A 1 307 ? -117.351 28.521 299.713 1.00 28.05 ? 307 PRO A N 1 ATOM 2314 C CA . PRO A 1 307 ? -117.716 29.941 299.812 1.00 26.32 ? 307 PRO A CA 1 ATOM 2315 C C . PRO A 1 307 ? -119.042 30.138 300.527 1.00 29.39 ? 307 PRO A C 1 ATOM 2316 O O . PRO A 1 307 ? -120.107 29.863 299.966 1.00 35.14 ? 307 PRO A O 1 ATOM 2317 C CB . PRO A 1 307 ? -117.789 30.396 298.348 1.00 22.18 ? 307 PRO A CB 1 ATOM 2318 C CG . PRO A 1 307 ? -117.059 29.352 297.569 1.00 24.54 ? 307 PRO A CG 1 ATOM 2319 C CD . PRO A 1 307 ? -117.243 28.073 298.315 1.00 28.91 ? 307 PRO A CD 1 ATOM 2320 N N . GLY A 1 308 ? -118.986 30.608 301.771 1.00 27.75 ? 308 GLY A N 1 ATOM 2321 C CA . GLY A 1 308 ? -120.183 30.810 302.561 1.00 31.27 ? 308 GLY A CA 1 ATOM 2322 C C . GLY A 1 308 ? -120.239 29.914 303.780 1.00 34.26 ? 308 GLY A C 1 ATOM 2323 O O . GLY A 1 308 ? -121.300 29.744 304.389 1.00 35.05 ? 308 GLY A O 1 ATOM 2324 N N . GLY A 1 309 ? -119.099 29.331 304.143 1.00 40.47 ? 309 GLY A N 1 ATOM 2325 C CA . GLY A 1 309 ? -119.025 28.453 305.295 1.00 40.27 ? 309 GLY A CA 1 ATOM 2326 C C . GLY A 1 309 ? -118.980 26.986 304.921 1.00 41.45 ? 309 GLY A C 1 ATOM 2327 O O . GLY A 1 309 ? -118.353 26.612 303.926 1.00 69.70 ? 309 GLY A O 1 ATOM 2328 N N . LYS A 1 310 ? -119.641 26.146 305.724 1.00 42.36 ? 310 LYS A N 1 ATOM 2329 C CA . LYS A 1 310 ? -119.802 24.714 305.471 1.00 43.49 ? 310 LYS A CA 1 ATOM 2330 C C . LYS A 1 310 ? -118.478 23.957 305.417 1.00 43.12 ? 310 LYS A C 1 ATOM 2331 O O . LYS A 1 310 ? -118.471 22.732 305.262 1.00 39.38 ? 310 LYS A O 1 ATOM 2332 C CB . LYS A 1 310 ? -120.563 24.472 304.163 1.00 45.95 ? 310 LYS A CB 1 ATOM 2333 C CG . LYS A 1 310 ? -121.587 25.532 303.802 1.00 64.70 ? 310 LYS A CG 1 ATOM 2334 C CD . LYS A 1 310 ? -121.762 25.582 302.302 1.00 72.37 ? 310 LYS A CD 1 ATOM 2335 C CE . LYS A 1 310 ? -122.097 26.976 301.814 1.00 62.87 ? 310 LYS A CE 1 ATOM 2336 N NZ . LYS A 1 310 ? -120.856 27.764 301.591 1.00 41.83 ? 310 LYS A NZ 1 ATOM 2337 N N . GLY A 1 311 ? -117.359 24.661 305.544 1.00 67.68 ? 311 GLY A N 1 ATOM 2338 C CA . GLY A 1 311 ? -116.061 24.046 305.388 1.00 64.08 ? 311 GLY A CA 1 ATOM 2339 C C . GLY A 1 311 ? -115.690 23.170 306.572 1.00 34.97 ? 311 GLY A C 1 ATOM 2340 O O . GLY A 1 311 ? -116.500 22.841 307.439 1.00 35.41 ? 311 GLY A O 1 ATOM 2341 N N . ALA A 1 312 ? -114.413 22.781 306.591 1.00 35.11 ? 312 ALA A N 1 ATOM 2342 C CA . ALA A 1 312 ? -113.903 21.995 307.708 1.00 35.72 ? 312 ALA A CA 1 ATOM 2343 C C . ALA A 1 312 ? -113.923 22.794 309.002 1.00 34.95 ? 312 ALA A C 1 ATOM 2344 O O . ALA A 1 312 ? -114.071 22.219 310.086 1.00 33.33 ? 312 ALA A O 1 ATOM 2345 C CB . ALA A 1 312 ? -112.488 21.502 307.406 1.00 35.00 ? 312 ALA A CB 1 ATOM 2346 N N . ASN A 1 313 ? -113.779 24.115 308.909 1.00 31.10 ? 313 ASN A N 1 ATOM 2347 C CA . ASN A 1 313 ? -113.860 24.981 310.073 1.00 31.57 ? 313 ASN A CA 1 ATOM 2348 C C . ASN A 1 313 ? -115.248 25.597 310.126 1.00 31.52 ? 313 ASN A C 1 ATOM 2349 O O . ASN A 1 313 ? -115.566 26.453 309.287 1.00 38.30 ? 313 ASN A O 1 ATOM 2350 C CB . ASN A 1 313 ? -112.794 26.072 310.009 1.00 31.72 ? 313 ASN A CB 1 ATOM 2351 C CG . ASN A 1 313 ? -112.579 26.757 311.342 1.00 30.50 ? 313 ASN A CG 1 ATOM 2352 O OD1 . ASN A 1 313 ? -113.374 26.602 312.269 1.00 37.26 ? 313 ASN A OD1 1 ATOM 2353 N ND2 . ASN A 1 313 ? -111.500 27.522 311.445 1.00 32.07 ? 313 ASN A ND2 1 ATOM 2354 N N . PRO A 1 314 ? -116.106 25.202 311.072 1.00 30.91 ? 314 PRO A N 1 ATOM 2355 C CA . PRO A 1 314 ? -117.457 25.781 311.130 1.00 33.20 ? 314 PRO A CA 1 ATOM 2356 C C . PRO A 1 314 ? -117.485 27.229 311.587 1.00 31.56 ? 314 PRO A C 1 ATOM 2357 O O . PRO A 1 314 ? -118.526 27.882 311.435 1.00 37.88 ? 314 PRO A O 1 ATOM 2358 C CB . PRO A 1 314 ? -118.182 24.873 312.131 1.00 31.31 ? 314 PRO A CB 1 ATOM 2359 C CG . PRO A 1 314 ? -117.093 24.358 313.011 1.00 30.24 ? 314 PRO A CG 1 ATOM 2360 C CD . PRO A 1 314 ? -115.888 24.194 312.124 1.00 31.57 ? 314 PRO A CD 1 ATOM 2361 N N . SER A 1 315 ? -116.386 27.751 312.136 1.00 30.91 ? 315 SER A N 1 ATOM 2362 C CA . SER A 1 315 ? -116.387 29.125 312.628 1.00 31.66 ? 315 SER A CA 1 ATOM 2363 C C . SER A 1 315 ? -116.382 30.135 311.489 1.00 29.70 ? 315 SER A C 1 ATOM 2364 O O . SER A 1 315 ? -116.841 31.269 311.667 1.00 31.00 ? 315 SER A O 1 ATOM 2365 C CB . SER A 1 315 ? -115.184 29.356 313.541 1.00 31.46 ? 315 SER A CB 1 ATOM 2366 O OG . SER A 1 315 ? -115.179 28.438 314.620 1.00 39.18 ? 315 SER A OG 1 ATOM 2367 N N . LEU A 1 316 ? -115.877 29.750 310.322 1.00 34.82 ? 316 LEU A N 1 ATOM 2368 C CA . LEU A 1 316 ? -115.770 30.656 309.190 1.00 31.14 ? 316 LEU A CA 1 ATOM 2369 C C . LEU A 1 316 ? -117.023 30.595 308.328 1.00 29.38 ? 316 LEU A C 1 ATOM 2370 O O . LEU A 1 316 ? -117.720 29.578 308.278 1.00 29.00 ? 316 LEU A O 1 ATOM 2371 C CB . LEU A 1 316 ? -114.541 30.318 308.346 1.00 32.97 ? 316 LEU A CB 1 ATOM 2372 C CG . LEU A 1 316 ? -113.244 30.095 309.125 1.00 33.48 ? 316 LEU A CG 1 ATOM 2373 C CD1 . LEU A 1 316 ? -112.144 29.583 308.209 1.00 44.72 ? 316 LEU A CD1 1 ATOM 2374 C CD2 . LEU A 1 316 ? -112.813 31.375 309.823 1.00 45.85 ? 316 LEU A CD2 1 ATOM 2375 N N . GLY A 1 317 ? -117.303 31.701 307.644 1.00 29.14 ? 317 GLY A N 1 ATOM 2376 C CA . GLY A 1 317 ? -118.440 31.760 306.749 1.00 29.96 ? 317 GLY A CA 1 ATOM 2377 C C . GLY A 1 317 ? -119.150 33.097 306.736 1.00 31.44 ? 317 GLY A C 1 ATOM 2378 O O . GLY A 1 317 ? -119.440 33.671 307.789 1.00 43.50 ? 317 GLY A O 1 ATOM 2379 N N . ASP A 1 318 ? -119.429 33.603 305.538 1.00 29.94 ? 318 ASP A N 1 ATOM 2380 C CA . ASP A 1 318 ? -120.224 34.818 305.379 1.00 30.59 ? 318 ASP A CA 1 ATOM 2381 C C . ASP A 1 318 ? -120.856 34.762 303.999 1.00 31.04 ? 318 ASP A C 1 ATOM 2382 O O . ASP A 1 318 ? -120.142 34.615 303.002 1.00 30.81 ? 318 ASP A O 1 ATOM 2383 C CB . ASP A 1 318 ? -119.363 36.071 305.548 1.00 30.26 ? 318 ASP A CB 1 ATOM 2384 C CG . ASP A 1 318 ? -120.193 37.333 305.694 1.00 30.80 ? 318 ASP A CG 1 ATOM 2385 O OD1 . ASP A 1 318 ? -121.429 37.221 305.823 1.00 37.44 ? 318 ASP A OD1 1 ATOM 2386 O OD2 . ASP A 1 318 ? -119.608 38.435 305.702 1.00 38.34 ? 318 ASP A OD2 1 ATOM 2387 N N . ALA A 1 319 ? -122.185 34.873 303.946 1.00 30.64 ? 319 ALA A N 1 ATOM 2388 C CA . ALA A 1 319 ? -122.926 34.569 302.724 1.00 31.94 ? 319 ALA A CA 1 ATOM 2389 C C . ALA A 1 319 ? -122.449 35.417 301.550 1.00 34.43 ? 319 ALA A C 1 ATOM 2390 O O . ALA A 1 319 ? -121.901 34.896 300.572 1.00 33.84 ? 319 ALA A O 1 ATOM 2391 C CB . ALA A 1 319 ? -124.424 34.770 302.960 1.00 66.38 ? 319 ALA A CB 1 ATOM 2392 N N . GLU A 1 320 ? -122.650 36.730 301.628 1.00 51.36 ? 320 GLU A N 1 ATOM 2393 C CA . GLU A 1 320 ? -122.382 37.613 300.502 1.00 43.41 ? 320 GLU A CA 1 ATOM 2394 C C . GLU A 1 320 ? -121.031 38.313 300.596 1.00 44.47 ? 320 GLU A C 1 ATOM 2395 O O . GLU A 1 320 ? -120.736 39.176 299.764 1.00 65.92 ? 320 GLU A O 1 ATOM 2396 C CB . GLU A 1 320 ? -123.511 38.634 300.358 1.00 48.94 ? 320 GLU A CB 1 ATOM 2397 C CG . GLU A 1 320 ? -124.830 38.001 299.930 1.00 62.37 ? 320 GLU A CG 1 ATOM 2398 C CD . GLU A 1 320 ? -125.964 39.000 299.827 1.00 65.65 ? 320 GLU A CD 1 ATOM 2399 O OE1 . GLU A 1 320 ? -125.779 40.160 300.249 1.00 55.55 ? 320 GLU A OE1 1 ATOM 2400 O OE2 . GLU A 1 320 ? -127.043 38.623 299.323 1.00 67.50 ? 320 GLU A OE2 1 ATOM 2401 N N . ARG A 1 321 ? -120.204 37.965 301.584 1.00 36.07 ? 321 ARG A N 1 ATOM 2402 C CA . ARG A 1 321 ? -118.797 38.346 301.516 1.00 28.75 ? 321 ARG A CA 1 ATOM 2403 C C . ARG A 1 321 ? -118.015 37.360 300.660 1.00 36.33 ? 321 ARG A C 1 ATOM 2404 O O . ARG A 1 321 ? -117.257 37.760 299.769 1.00 40.23 ? 321 ARG A O 1 ATOM 2405 C CB . ARG A 1 321 ? -118.182 38.419 302.914 1.00 26.29 ? 321 ARG A CB 1 ATOM 2406 C CG . ARG A 1 321 ? -116.934 39.287 302.971 1.00 26.15 ? 321 ARG A CG 1 ATOM 2407 C CD . ARG A 1 321 ? -116.186 39.157 304.289 1.00 26.03 ? 321 ARG A CD 1 ATOM 2408 N NE . ARG A 1 321 ? -117.047 38.752 305.395 1.00 42.63 ? 321 ARG A NE 1 ATOM 2409 C CZ . ARG A 1 321 ? -116.602 38.481 306.617 1.00 34.79 ? 321 ARG A CZ 1 ATOM 2410 N NH1 . ARG A 1 321 ? -115.307 38.572 306.886 1.00 27.70 ? 321 ARG A NH1 1 ATOM 2411 N NH2 . ARG A 1 321 ? -117.448 38.118 307.570 1.00 32.86 ? 321 ARG A NH2 1 ATOM 2412 N N . ASP A 1 322 ? -118.194 36.064 300.921 1.00 37.88 ? 322 ASP A N 1 ATOM 2413 C CA . ASP A 1 322 ? -117.507 35.041 300.145 1.00 27.32 ? 322 ASP A CA 1 ATOM 2414 C C . ASP A 1 322 ? -117.983 35.019 298.700 1.00 26.94 ? 322 ASP A C 1 ATOM 2415 O O . ASP A 1 322 ? -117.195 34.725 297.796 1.00 24.12 ? 322 ASP A O 1 ATOM 2416 C CB . ASP A 1 322 ? -117.716 33.673 300.791 1.00 29.70 ? 322 ASP A CB 1 ATOM 2417 C CG . ASP A 1 322 ? -117.131 33.594 302.185 1.00 33.53 ? 322 ASP A CG 1 ATOM 2418 O OD1 . ASP A 1 322 ? -116.239 34.408 302.503 1.00 39.24 ? 322 ASP A OD1 1 ATOM 2419 O OD2 . ASP A 1 322 ? -117.566 32.721 302.965 1.00 34.70 ? 322 ASP A OD2 1 ATOM 2420 N N . ALA A 1 323 ? -119.260 35.331 298.466 1.00 30.18 ? 323 ALA A N 1 ATOM 2421 C CA . ALA A 1 323 ? -119.800 35.284 297.111 1.00 28.78 ? 323 ALA A CA 1 ATOM 2422 C C . ALA A 1 323 ? -119.108 36.292 296.204 1.00 23.81 ? 323 ALA A C 1 ATOM 2423 O O . ALA A 1 323 ? -118.905 36.029 295.013 1.00 18.45 ? 323 ALA A O 1 ATOM 2424 C CB . ALA A 1 323 ? -121.307 35.533 297.138 1.00 34.74 ? 323 ALA A CB 1 ATOM 2425 N N . LYS A 1 324 ? -118.742 37.454 296.745 1.00 26.31 ? 324 LYS A N 1 ATOM 2426 C CA . LYS A 1 324 ? -118.010 38.447 295.970 1.00 25.18 ? 324 LYS A CA 1 ATOM 2427 C C . LYS A 1 324 ? -116.508 38.194 295.996 1.00 22.22 ? 324 LYS A C 1 ATOM 2428 O O . LYS A 1 324 ? -115.824 38.423 294.992 1.00 21.61 ? 324 LYS A O 1 ATOM 2429 C CB . LYS A 1 324 ? -118.316 39.854 296.489 1.00 23.11 ? 324 LYS A CB 1 ATOM 2430 C CG . LYS A 1 324 ? -117.718 40.965 295.644 1.00 20.66 ? 324 LYS A CG 1 ATOM 2431 C CD . LYS A 1 324 ? -118.283 40.946 294.233 1.00 20.62 ? 324 LYS A CD 1 ATOM 2432 C CE . LYS A 1 324 ? -117.489 41.851 293.305 1.00 23.44 ? 324 LYS A CE 1 ATOM 2433 N NZ . LYS A 1 324 ? -117.368 43.233 293.843 1.00 34.85 ? 324 LYS A NZ 1 ATOM 2434 N N . THR A 1 325 ? -115.982 37.723 297.130 1.00 23.51 ? 325 THR A N 1 ATOM 2435 C CA . THR A 1 325 ? -114.570 37.363 297.198 1.00 24.56 ? 325 THR A CA 1 ATOM 2436 C C . THR A 1 325 ? -114.247 36.236 296.225 1.00 26.60 ? 325 THR A C 1 ATOM 2437 O O . THR A 1 325 ? -113.200 36.252 295.567 1.00 20.25 ? 325 THR A O 1 ATOM 2438 C CB . THR A 1 325 ? -114.197 36.961 298.625 1.00 22.18 ? 325 THR A CB 1 ATOM 2439 O OG1 . THR A 1 325 ? -114.528 38.025 299.526 1.00 20.98 ? 325 THR A OG1 1 ATOM 2440 C CG2 . THR A 1 325 ? -112.709 36.667 298.727 1.00 19.26 ? 325 THR A CG2 1 ATOM 2441 N N . TYR A 1 326 ? -115.142 35.250 296.118 1.00 21.82 ? 326 TYR A N 1 ATOM 2442 C CA . TYR A 1 326 ? -114.950 34.167 295.160 1.00 19.22 ? 326 TYR A CA 1 ATOM 2443 C C . TYR A 1 326 ? -114.917 34.685 293.729 1.00 19.56 ? 326 TYR A C 1 ATOM 2444 O O . TYR A 1 326 ? -114.201 34.134 292.886 1.00 20.15 ? 326 TYR A O 1 ATOM 2445 C CB . TYR A 1 326 ? -116.060 33.128 295.329 1.00 19.27 ? 326 TYR A CB 1 ATOM 2446 C CG . TYR A 1 326 ? -115.895 31.877 294.498 1.00 20.67 ? 326 TYR A CG 1 ATOM 2447 C CD1 . TYR A 1 326 ? -115.110 30.823 294.942 1.00 16.62 ? 326 TYR A CD1 1 ATOM 2448 C CD2 . TYR A 1 326 ? -116.542 31.743 293.278 1.00 23.16 ? 326 TYR A CD2 1 ATOM 2449 C CE1 . TYR A 1 326 ? -114.965 29.675 294.188 1.00 16.41 ? 326 TYR A CE1 1 ATOM 2450 C CE2 . TYR A 1 326 ? -116.405 30.599 292.519 1.00 19.36 ? 326 TYR A CE2 1 ATOM 2451 C CZ . TYR A 1 326 ? -115.615 29.569 292.977 1.00 17.37 ? 326 TYR A CZ 1 ATOM 2452 O OH . TYR A 1 326 ? -115.475 28.429 292.221 1.00 20.23 ? 326 TYR A OH 1 ATOM 2453 N N . ILE A 1 327 ? -115.676 35.742 293.437 1.00 20.59 ? 327 ILE A N 1 ATOM 2454 C CA . ILE A 1 327 ? -115.658 36.326 292.101 1.00 19.45 ? 327 ILE A CA 1 ATOM 2455 C C . ILE A 1 327 ? -114.383 37.128 291.885 1.00 21.90 ? 327 ILE A C 1 ATOM 2456 O O . ILE A 1 327 ? -113.711 36.987 290.857 1.00 22.12 ? 327 ILE A O 1 ATOM 2457 C CB . ILE A 1 327 ? -116.912 37.192 291.879 1.00 20.64 ? 327 ILE A CB 1 ATOM 2458 C CG1 . ILE A 1 327 ? -118.173 36.330 291.925 1.00 21.58 ? 327 ILE A CG1 1 ATOM 2459 C CG2 . ILE A 1 327 ? -116.820 37.928 290.552 1.00 21.92 ? 327 ILE A CG2 1 ATOM 2460 C CD1 . ILE A 1 327 ? -118.190 35.221 290.902 1.00 27.98 ? 327 ILE A CD1 1 ATOM 2461 N N . LEU A 1 328 ? -114.030 37.979 292.852 1.00 23.97 ? 328 LEU A N 1 ATOM 2462 C CA . LEU A 1 328 ? -112.822 38.788 292.723 1.00 26.64 ? 328 LEU A CA 1 ATOM 2463 C C . LEU A 1 328 ? -111.571 37.925 292.648 1.00 31.93 ? 328 LEU A C 1 ATOM 2464 O O . LEU A 1 328 ? -110.611 38.283 291.957 1.00 25.07 ? 328 LEU A O 1 ATOM 2465 C CB . LEU A 1 328 ? -112.720 39.768 293.892 1.00 23.68 ? 328 LEU A CB 1 ATOM 2466 C CG . LEU A 1 328 ? -113.775 40.873 293.958 1.00 26.11 ? 328 LEU A CG 1 ATOM 2467 C CD1 . LEU A 1 328 ? -113.619 41.687 295.232 1.00 27.76 ? 328 LEU A CD1 1 ATOM 2468 C CD2 . LEU A 1 328 ? -113.693 41.771 292.732 1.00 28.03 ? 328 LEU A CD2 1 ATOM 2469 N N . LEU A 1 329 ? -111.562 36.789 293.350 1.00 46.11 ? 329 LEU A N 1 ATOM 2470 C CA . LEU A 1 329 ? -110.409 35.896 293.312 1.00 26.66 ? 329 LEU A CA 1 ATOM 2471 C C . LEU A 1 329 ? -110.201 35.326 291.914 1.00 23.78 ? 329 LEU A C 1 ATOM 2472 O O . LEU A 1 329 ? -109.075 35.296 291.404 1.00 23.21 ? 329 LEU A O 1 ATOM 2473 C CB . LEU A 1 329 ? -110.589 34.772 294.334 1.00 24.68 ? 329 LEU A CB 1 ATOM 2474 C CG . LEU A 1 329 ? -109.406 33.836 294.581 1.00 22.27 ? 329 LEU A CG 1 ATOM 2475 C CD1 . LEU A 1 329 ? -108.163 34.619 294.945 1.00 21.68 ? 329 LEU A CD1 1 ATOM 2476 C CD2 . LEU A 1 329 ? -109.745 32.839 295.676 1.00 25.89 ? 329 LEU A CD2 1 ATOM 2477 N N . LEU A 1 330 ? -111.281 34.873 291.275 1.00 22.91 ? 330 LEU A N 1 ATOM 2478 C CA . LEU A 1 330 ? -111.157 34.283 289.946 1.00 23.60 ? 330 LEU A CA 1 ATOM 2479 C C . LEU A 1 330 ? -110.844 35.340 288.895 1.00 26.83 ? 330 LEU A C 1 ATOM 2480 O O . LEU A 1 330 ? -110.075 35.084 287.961 1.00 25.58 ? 330 LEU A O 1 ATOM 2481 C CB . LEU A 1 330 ? -112.439 33.534 289.587 1.00 24.38 ? 330 LEU A CB 1 ATOM 2482 C CG . LEU A 1 330 ? -112.836 32.396 290.526 1.00 26.28 ? 330 LEU A CG 1 ATOM 2483 C CD1 . LEU A 1 330 ? -114.159 31.792 290.090 1.00 26.91 ? 330 LEU A CD1 1 ATOM 2484 C CD2 . LEU A 1 330 ? -111.746 31.336 290.587 1.00 22.63 ? 330 LEU A CD2 1 ATOM 2485 N N . GLU A 1 331 ? -111.437 36.529 289.024 1.00 28.61 ? 331 GLU A N 1 ATOM 2486 C CA . GLU A 1 331 ? -111.179 37.592 288.058 1.00 26.99 ? 331 GLU A CA 1 ATOM 2487 C C . GLU A 1 331 ? -109.710 37.993 288.059 1.00 27.47 ? 331 GLU A C 1 ATOM 2488 O O . GLU A 1 331 ? -109.110 38.188 286.995 1.00 24.76 ? 331 GLU A O 1 ATOM 2489 C CB . GLU A 1 331 ? -112.064 38.802 288.358 1.00 26.63 ? 331 GLU A CB 1 ATOM 2490 C CG . GLU A 1 331 ? -113.546 38.567 288.123 1.00 33.54 ? 331 GLU A CG 1 ATOM 2491 C CD . GLU A 1 331 ? -114.386 39.780 288.466 1.00 27.43 ? 331 GLU A CD 1 ATOM 2492 O OE1 . GLU A 1 331 ? -113.859 40.703 289.122 1.00 23.19 ? 331 GLU A OE1 1 ATOM 2493 O OE2 . GLU A 1 331 ? -115.573 39.812 288.080 1.00 21.79 ? 331 GLU A OE2 1 ATOM 2494 N N . GLU A 1 332 ? -109.112 38.116 289.244 1.00 27.75 ? 332 GLU A N 1 ATOM 2495 C CA . GLU A 1 332 ? -107.713 38.516 289.330 1.00 27.98 ? 332 GLU A CA 1 ATOM 2496 C C . GLU A 1 332 ? -106.770 37.375 288.972 1.00 26.19 ? 332 GLU A C 1 ATOM 2497 O O . GLU A 1 332 ? -105.694 37.620 288.413 1.00 24.49 ? 332 GLU A O 1 ATOM 2498 C CB . GLU A 1 332 ? -107.407 39.042 290.733 1.00 27.12 ? 332 GLU A CB 1 ATOM 2499 C CG . GLU A 1 332 ? -108.225 40.265 291.114 1.00 28.81 ? 332 GLU A CG 1 ATOM 2500 C CD . GLU A 1 332 ? -108.262 40.495 292.609 1.00 30.48 ? 332 GLU A CD 1 ATOM 2501 O OE1 . GLU A 1 332 ? -107.620 39.717 293.342 1.00 35.88 ? 332 GLU A OE1 1 ATOM 2502 O OE2 . GLU A 1 332 ? -108.940 41.445 293.053 1.00 31.84 ? 332 GLU A OE2 1 ATOM 2503 N N . LEU A 1 333 ? -107.147 36.132 289.280 1.00 26.67 ? 333 LEU A N 1 ATOM 2504 C CA . LEU A 1 333 ? -106.328 34.996 288.872 1.00 25.29 ? 333 LEU A CA 1 ATOM 2505 C C . LEU A 1 333 ? -106.348 34.819 287.359 1.00 24.06 ? 333 LEU A C 1 ATOM 2506 O O . LEU A 1 333 ? -105.314 34.522 286.751 1.00 25.17 ? 333 LEU A O 1 ATOM 2507 C CB . LEU A 1 333 ? -106.806 33.722 289.568 1.00 22.47 ? 333 LEU A CB 1 ATOM 2508 C CG . LEU A 1 333 ? -106.383 33.549 291.027 1.00 18.32 ? 333 LEU A CG 1 ATOM 2509 C CD1 . LEU A 1 333 ? -106.941 32.259 291.588 1.00 21.96 ? 333 LEU A CD1 1 ATOM 2510 C CD2 . LEU A 1 333 ? -104.871 33.561 291.141 1.00 19.53 ? 333 LEU A CD2 1 ATOM 2511 N N . ARG A 1 334 ? -107.515 34.999 286.735 1.00 23.78 ? 334 ARG A N 1 ATOM 2512 C CA . ARG A 1 334 ? -107.597 34.896 285.282 1.00 25.81 ? 334 ARG A CA 1 ATOM 2513 C C . ARG A 1 334 ? -106.766 35.980 284.609 1.00 28.89 ? 334 ARG A C 1 ATOM 2514 O O . ARG A 1 334 ? -106.067 35.715 283.624 1.00 26.52 ? 334 ARG A O 1 ATOM 2515 C CB . ARG A 1 334 ? -109.055 34.978 284.833 1.00 27.04 ? 334 ARG A CB 1 ATOM 2516 C CG . ARG A 1 334 ? -109.267 34.798 283.337 1.00 23.67 ? 334 ARG A CG 1 ATOM 2517 C CD . ARG A 1 334 ? -108.965 33.375 282.894 1.00 27.76 ? 334 ARG A CD 1 ATOM 2518 N NE . ARG A 1 334 ? -107.607 33.227 282.379 1.00 28.03 ? 334 ARG A NE 1 ATOM 2519 C CZ . ARG A 1 334 ? -107.072 32.066 282.015 1.00 25.70 ? 334 ARG A CZ 1 ATOM 2520 N NH1 . ARG A 1 334 ? -107.778 30.949 282.113 1.00 22.27 ? 334 ARG A NH1 1 ATOM 2521 N NH2 . ARG A 1 334 ? -105.830 32.021 281.554 1.00 37.32 ? 334 ARG A NH2 1 ATOM 2522 N N . ALA A 1 335 ? -106.828 37.208 285.128 1.00 26.59 ? 335 ALA A N 1 ATOM 2523 C CA . ALA A 1 335 ? -106.016 38.286 284.574 1.00 24.56 ? 335 ALA A CA 1 ATOM 2524 C C . ALA A 1 335 ? -104.531 38.018 284.779 1.00 23.83 ? 335 ALA A C 1 ATOM 2525 O O . ALA A 1 335 ? -103.711 38.332 283.908 1.00 27.45 ? 335 ALA A O 1 ATOM 2526 C CB . ALA A 1 335 ? -106.414 39.621 285.202 1.00 25.36 ? 335 ALA A CB 1 ATOM 2527 N N . MET A 1 336 ? -104.167 37.437 285.924 1.00 22.14 ? 336 MET A N 1 ATOM 2528 C CA . MET A 1 336 ? -102.772 37.081 286.157 1.00 22.28 ? 336 MET A CA 1 ATOM 2529 C C . MET A 1 336 ? -102.319 35.989 285.197 1.00 24.42 ? 336 MET A C 1 ATOM 2530 O O . MET A 1 336 ? -101.196 36.034 284.682 1.00 26.69 ? 336 MET A O 1 ATOM 2531 C CB . MET A 1 336 ? -102.582 36.647 287.613 1.00 19.50 ? 336 MET A CB 1 ATOM 2532 C CG . MET A 1 336 ? -101.189 36.135 287.961 1.00 18.54 ? 336 MET A CG 1 ATOM 2533 S SD . MET A 1 336 ? -100.944 34.379 287.623 1.00 19.15 ? 336 MET A SD 1 ATOM 2534 C CE . MET A 1 336 ? -102.347 33.672 288.480 1.00 22.92 ? 336 MET A CE 1 ATOM 2535 N N . LEU A 1 337 ? -103.179 34.998 284.946 1.00 24.08 ? 337 LEU A N 1 ATOM 2536 C CA . LEU A 1 337 ? -102.840 33.953 283.987 1.00 23.03 ? 337 LEU A CA 1 ATOM 2537 C C . LEU A 1 337 ? -102.737 34.502 282.570 1.00 25.85 ? 337 LEU A C 1 ATOM 2538 O O . LEU A 1 337 ? -101.931 34.007 281.775 1.00 25.17 ? 337 LEU A O 1 ATOM 2539 C CB . LEU A 1 337 ? -103.872 32.829 284.044 1.00 22.16 ? 337 LEU A CB 1 ATOM 2540 C CG . LEU A 1 337 ? -103.912 32.002 285.329 1.00 21.18 ? 337 LEU A CG 1 ATOM 2541 C CD1 . LEU A 1 337 ? -104.999 30.945 285.246 1.00 22.91 ? 337 LEU A CD1 1 ATOM 2542 C CD2 . LEU A 1 337 ? -102.562 31.365 285.584 1.00 19.52 ? 337 LEU A CD2 1 ATOM 2543 N N . ASP A 1 338 ? -103.540 35.516 282.236 1.00 27.92 ? 338 ASP A N 1 ATOM 2544 C CA . ASP A 1 338 ? -103.436 36.133 280.918 1.00 27.63 ? 338 ASP A CA 1 ATOM 2545 C C . ASP A 1 338 ? -102.077 36.787 280.715 1.00 28.29 ? 338 ASP A C 1 ATOM 2546 O O . ASP A 1 338 ? -101.568 36.826 279.589 1.00 31.75 ? 338 ASP A O 1 ATOM 2547 C CB . ASP A 1 338 ? -104.554 37.157 280.724 1.00 25.75 ? 338 ASP A CB 1 ATOM 2548 C CG . ASP A 1 338 ? -105.930 36.525 280.726 1.00 33.95 ? 338 ASP A CG 1 ATOM 2549 O OD1 . ASP A 1 338 ? -106.032 35.318 280.420 1.00 39.26 ? 338 ASP A OD1 1 ATOM 2550 O OD2 . ASP A 1 338 ? -106.911 37.234 281.033 1.00 42.17 ? 338 ASP A OD2 1 ATOM 2551 N N . ASP A 1 339 ? -101.476 37.307 281.788 1.00 24.91 ? 339 ASP A N 1 ATOM 2552 C CA . ASP A 1 339 ? -100.126 37.849 281.682 1.00 25.85 ? 339 ASP A CA 1 ATOM 2553 C C . ASP A 1 339 ? -99.109 36.740 281.450 1.00 28.16 ? 339 ASP A C 1 ATOM 2554 O O . ASP A 1 339 ? -98.163 36.910 280.672 1.00 30.66 ? 339 ASP A O 1 ATOM 2555 C CB . ASP A 1 339 ? -99.780 38.646 282.938 1.00 30.44 ? 339 ASP A CB 1 ATOM 2556 C CG . ASP A 1 339 ? -100.680 39.850 283.129 1.00 44.59 ? 339 ASP A CG 1 ATOM 2557 O OD1 . ASP A 1 339 ? -100.747 40.695 282.212 1.00 55.16 ? 339 ASP A OD1 1 ATOM 2558 O OD2 . ASP A 1 339 ? -101.321 39.952 284.197 1.00 42.17 ? 339 ASP A OD2 1 ATOM 2559 N N . LEU A 1 340 ? -99.289 35.596 282.115 1.00 26.22 ? 340 LEU A N 1 ATOM 2560 C CA . LEU A 1 340 ? -98.417 34.454 281.868 1.00 28.78 ? 340 LEU A CA 1 ATOM 2561 C C . LEU A 1 340 ? -98.576 33.931 280.448 1.00 25.64 ? 340 LEU A C 1 ATOM 2562 O O . LEU A 1 340 ? -97.604 33.460 279.847 1.00 37.57 ? 340 LEU A O 1 ATOM 2563 C CB . LEU A 1 340 ? -98.708 33.341 282.876 1.00 23.79 ? 340 LEU A CB 1 ATOM 2564 C CG . LEU A 1 340 ? -98.009 33.420 284.234 1.00 22.70 ? 340 LEU A CG 1 ATOM 2565 C CD1 . LEU A 1 340 ? -98.436 32.261 285.119 1.00 19.56 ? 340 LEU A CD1 1 ATOM 2566 C CD2 . LEU A 1 340 ? -96.500 33.432 284.059 1.00 28.34 ? 340 LEU A CD2 1 ATOM 2567 N N . GLU A 1 341 ? -99.789 34.007 279.896 1.00 24.40 ? 341 GLU A N 1 ATOM 2568 C CA . GLU A 1 341 ? -100.019 33.512 278.543 1.00 26.52 ? 341 GLU A CA 1 ATOM 2569 C C . GLU A 1 341 ? -99.263 34.341 277.513 1.00 27.65 ? 341 GLU A C 1 ATOM 2570 O O . GLU A 1 341 ? -98.732 33.797 276.538 1.00 34.27 ? 341 GLU A O 1 ATOM 2571 C CB . GLU A 1 341 ? -101.516 33.510 278.234 1.00 29.56 ? 341 GLU A CB 1 ATOM 2572 C CG . GLU A 1 341 ? -102.308 32.463 279.000 1.00 28.66 ? 341 GLU A CG 1 ATOM 2573 C CD . GLU A 1 341 ? -103.765 32.420 278.588 1.00 27.97 ? 341 GLU A CD 1 ATOM 2574 O OE1 . GLU A 1 341 ? -104.175 33.269 277.770 1.00 30.44 ? 341 GLU A OE1 1 ATOM 2575 O OE2 . GLU A 1 341 ? -104.499 31.539 279.081 1.00 24.03 ? 341 GLU A OE2 1 ATOM 2576 N N . ALA A 1 342 ? -99.204 35.659 277.708 1.00 28.37 ? 342 ALA A N 1 ATOM 2577 C CA . ALA A 1 342 ? -98.483 36.512 276.771 1.00 39.21 ? 342 ALA A CA 1 ATOM 2578 C C . ALA A 1 342 ? -96.983 36.503 277.029 1.00 34.75 ? 342 ALA A C 1 ATOM 2579 O O . ALA A 1 342 ? -96.197 36.711 276.097 1.00 30.11 ? 342 ALA A O 1 ATOM 2580 C CB . ALA A 1 342 ? -99.019 37.943 276.843 1.00 43.72 ? 342 ALA A CB 1 ATOM 2581 N N . GLN A 1 343 ? -96.568 36.262 278.273 1.00 40.28 ? 343 GLN A N 1 ATOM 2582 C CA . GLN A 1 343 ? -95.147 36.268 278.601 1.00 35.64 ? 343 GLN A CA 1 ATOM 2583 C C . GLN A 1 343 ? -94.483 34.942 278.249 1.00 29.97 ? 343 GLN A C 1 ATOM 2584 O O . GLN A 1 343 ? -93.336 34.922 277.787 1.00 33.49 ? 343 GLN A O 1 ATOM 2585 C CB . GLN A 1 343 ? -94.960 36.597 280.085 1.00 35.83 ? 343 GLN A CB 1 ATOM 2586 C CG . GLN A 1 343 ? -93.633 36.154 280.678 1.00 50.72 ? 343 GLN A CG 1 ATOM 2587 C CD . GLN A 1 343 ? -93.522 36.481 282.155 1.00 56.24 ? 343 GLN A CD 1 ATOM 2588 O OE1 . GLN A 1 343 ? -94.312 37.259 282.691 1.00 53.30 ? 343 GLN A OE1 1 ATOM 2589 N NE2 . GLN A 1 343 ? -92.538 35.888 282.821 1.00 51.55 ? 343 GLN A NE2 1 ATOM 2590 N N . THR A 1 344 ? -95.188 33.827 278.446 1.00 29.03 ? 344 THR A N 1 ATOM 2591 C CA . THR A 1 344 ? -94.640 32.510 278.152 1.00 26.36 ? 344 THR A CA 1 ATOM 2592 C C . THR A 1 344 ? -95.079 31.957 276.803 1.00 25.93 ? 344 THR A C 1 ATOM 2593 O O . THR A 1 344 ? -94.468 30.996 276.321 1.00 27.45 ? 344 THR A O 1 ATOM 2594 C CB . THR A 1 344 ? -95.037 31.510 279.245 1.00 27.13 ? 344 THR A CB 1 ATOM 2595 O OG1 . THR A 1 344 ? -96.444 31.252 279.172 1.00 26.14 ? 344 THR A OG1 1 ATOM 2596 C CG2 . THR A 1 344 ? -94.700 32.063 280.620 1.00 43.65 ? 344 THR A CG2 1 ATOM 2597 N N . GLY A 1 345 ? -96.109 32.530 276.186 1.00 26.38 ? 345 GLY A N 1 ATOM 2598 C CA . GLY A 1 345 ? -96.627 32.003 274.941 1.00 26.65 ? 345 GLY A CA 1 ATOM 2599 C C . GLY A 1 345 ? -97.487 30.769 275.082 1.00 26.44 ? 345 GLY A C 1 ATOM 2600 O O . GLY A 1 345 ? -97.879 30.185 274.066 1.00 24.90 ? 345 GLY A O 1 ATOM 2601 N N . ARG A 1 346 ? -97.795 30.356 276.307 1.00 25.84 ? 346 ARG A N 1 ATOM 2602 C CA . ARG A 1 346 ? -98.585 29.167 276.573 1.00 25.02 ? 346 ARG A CA 1 ATOM 2603 C C . ARG A 1 346 ? -100.037 29.552 276.839 1.00 24.65 ? 346 ARG A C 1 ATOM 2604 O O . ARG A 1 346 ? -100.399 30.730 276.890 1.00 25.35 ? 346 ARG A O 1 ATOM 2605 C CB . ARG A 1 346 ? -98.000 28.402 277.761 1.00 27.06 ? 346 ARG A CB 1 ATOM 2606 C CG . ARG A 1 346 ? -96.540 28.021 277.601 1.00 43.63 ? 346 ARG A CG 1 ATOM 2607 C CD . ARG A 1 346 ? -95.965 27.497 278.906 1.00 39.24 ? 346 ARG A CD 1 ATOM 2608 N NE . ARG A 1 346 ? -96.807 26.464 279.501 1.00 43.48 ? 346 ARG A NE 1 ATOM 2609 C CZ . ARG A 1 346 ? -96.576 25.902 280.683 1.00 40.21 ? 346 ARG A CZ 1 ATOM 2610 N NH1 . ARG A 1 346 ? -95.526 26.276 281.402 1.00 32.90 ? 346 ARG A NH1 1 ATOM 2611 N NH2 . ARG A 1 346 ? -97.394 24.968 281.148 1.00 29.26 ? 346 ARG A NH2 1 ATOM 2612 N N . VAL A 1 347 ? -100.880 28.537 277.011 1.00 22.92 ? 347 VAL A N 1 ATOM 2613 C CA . VAL A 1 347 ? -102.252 28.718 277.466 1.00 25.25 ? 347 VAL A CA 1 ATOM 2614 C C . VAL A 1 347 ? -102.344 28.191 278.893 1.00 24.42 ? 347 VAL A C 1 ATOM 2615 O O . VAL A 1 347 ? -101.809 27.120 279.209 1.00 23.24 ? 347 VAL A O 1 ATOM 2616 C CB . VAL A 1 347 ? -103.265 28.035 276.526 1.00 25.17 ? 347 VAL A CB 1 ATOM 2617 C CG1 . VAL A 1 347 ? -102.971 28.409 275.082 1.00 22.45 ? 347 VAL A CG1 1 ATOM 2618 C CG2 . VAL A 1 347 ? -103.252 26.522 276.682 1.00 30.64 ? 347 VAL A CG2 1 ATOM 2619 N N . TYR A 1 348 ? -102.978 28.970 279.765 1.00 27.02 ? 348 TYR A N 1 ATOM 2620 C CA . TYR A 1 348 ? -103.096 28.642 281.178 1.00 28.97 ? 348 TYR A CA 1 ATOM 2621 C C . TYR A 1 348 ? -104.569 28.619 281.554 1.00 29.74 ? 348 TYR A C 1 ATOM 2622 O O . TYR A 1 348 ? -105.323 29.523 281.178 1.00 35.90 ? 348 TYR A O 1 ATOM 2623 C CB . TYR A 1 348 ? -102.332 29.650 282.043 1.00 26.57 ? 348 TYR A CB 1 ATOM 2624 C CG . TYR A 1 348 ? -100.840 29.401 282.109 1.00 26.05 ? 348 TYR A CG 1 ATOM 2625 C CD1 . TYR A 1 348 ? -100.292 28.613 283.112 1.00 26.47 ? 348 TYR A CD1 1 ATOM 2626 C CD2 . TYR A 1 348 ? -99.980 29.955 281.169 1.00 24.49 ? 348 TYR A CD2 1 ATOM 2627 C CE1 . TYR A 1 348 ? -98.930 28.384 283.179 1.00 31.99 ? 348 TYR A CE1 1 ATOM 2628 C CE2 . TYR A 1 348 ? -98.616 29.730 281.227 1.00 25.12 ? 348 TYR A CE2 1 ATOM 2629 C CZ . TYR A 1 348 ? -98.097 28.944 282.234 1.00 29.10 ? 348 TYR A CZ 1 ATOM 2630 O OH . TYR A 1 348 ? -96.742 28.715 282.299 1.00 26.14 ? 348 TYR A OH 1 ATOM 2631 N N . GLU A 1 349 ? -104.972 27.590 282.290 1.00 25.31 ? 349 GLU A N 1 ATOM 2632 C CA . GLU A 1 349 ? -106.368 27.374 282.633 1.00 27.58 ? 349 GLU A CA 1 ATOM 2633 C C . GLU A 1 349 ? -106.639 27.760 284.081 1.00 24.51 ? 349 GLU A C 1 ATOM 2634 O O . GLU A 1 349 ? -105.761 27.681 284.942 1.00 23.97 ? 349 GLU A O 1 ATOM 2635 C CB . GLU A 1 349 ? -106.758 25.913 282.402 1.00 27.09 ? 349 GLU A CB 1 ATOM 2636 C CG . GLU A 1 349 ? -106.707 25.494 280.946 1.00 32.50 ? 349 GLU A CG 1 ATOM 2637 C CD . GLU A 1 349 ? -106.961 24.015 280.753 1.00 24.89 ? 349 GLU A CD 1 ATOM 2638 O OE1 . GLU A 1 349 ? -107.586 23.394 281.638 1.00 24.64 ? 349 GLU A OE1 1 ATOM 2639 O OE2 . GLU A 1 349 ? -106.536 23.475 279.712 1.00 26.22 ? 349 GLU A OE2 1 ATOM 2640 N N . LEU A 1 350 ? -107.874 28.180 284.339 1.00 23.05 ? 350 LEU A N 1 ATOM 2641 C CA . LEU A 1 350 ? -108.321 28.545 285.681 1.00 21.00 ? 350 LEU A CA 1 ATOM 2642 C C . LEU A 1 350 ? -109.594 27.757 285.966 1.00 22.31 ? 350 LEU A C 1 ATOM 2643 O O . LEU A 1 350 ? -110.668 28.099 285.465 1.00 22.60 ? 350 LEU A O 1 ATOM 2644 C CB . LEU A 1 350 ? -108.555 30.047 285.799 1.00 21.41 ? 350 LEU A CB 1 ATOM 2645 C CG . LEU A 1 350 ? -109.114 30.536 287.134 1.00 22.21 ? 350 LEU A CG 1 ATOM 2646 C CD1 . LEU A 1 350 ? -108.237 30.075 288.287 1.00 17.98 ? 350 LEU A CD1 1 ATOM 2647 C CD2 . LEU A 1 350 ? -109.246 32.048 287.129 1.00 27.12 ? 350 LEU A CD2 1 ATOM 2648 N N . THR A 1 351 ? -109.470 26.700 286.759 1.00 23.92 ? 351 THR A N 1 ATOM 2649 C CA . THR A 1 351 ? -110.589 25.836 287.099 1.00 25.92 ? 351 THR A CA 1 ATOM 2650 C C . THR A 1 351 ? -110.944 25.993 288.571 1.00 23.17 ? 351 THR A C 1 ATOM 2651 O O . THR A 1 351 ? -110.240 26.650 289.342 1.00 21.49 ? 351 THR A O 1 ATOM 2652 C CB . THR A 1 351 ? -110.263 24.372 286.785 1.00 29.43 ? 351 THR A CB 1 ATOM 2653 O OG1 . THR A 1 351 ? -109.234 23.911 287.668 1.00 27.08 ? 351 THR A OG1 1 ATOM 2654 C CG2 . THR A 1 351 ? -109.791 24.229 285.347 1.00 49.02 ? 351 THR A CG2 1 ATOM 2655 N N . SER A 1 352 ? -112.056 25.371 288.955 1.00 23.38 ? 352 SER A N 1 ATOM 2656 C CA . SER A 1 352 ? -112.519 25.435 290.335 1.00 21.40 ? 352 SER A CA 1 ATOM 2657 C C . SER A 1 352 ? -113.459 24.272 290.603 1.00 20.05 ? 352 SER A C 1 ATOM 2658 O O . SER A 1 352 ? -114.351 23.996 289.796 1.00 21.98 ? 352 SER A O 1 ATOM 2659 C CB . SER A 1 352 ? -113.226 26.763 290.621 1.00 21.01 ? 352 SER A CB 1 ATOM 2660 O OG . SER A 1 352 ? -113.818 26.753 291.908 1.00 17.50 ? 352 SER A OG 1 ATOM 2661 N N . ALA A 1 353 ? -113.256 23.600 291.731 1.00 18.92 ? 353 ALA A N 1 ATOM 2662 C CA . ALA A 1 353 ? -114.159 22.551 292.178 1.00 22.06 ? 353 ALA A CA 1 ATOM 2663 C C . ALA A 1 353 ? -115.188 23.150 293.126 1.00 21.06 ? 353 ALA A C 1 ATOM 2664 O O . ALA A 1 353 ? -114.831 23.844 294.083 1.00 21.34 ? 353 ALA A O 1 ATOM 2665 C CB . ALA A 1 353 ? -113.392 21.423 292.867 1.00 21.57 ? 353 ALA A CB 1 ATOM 2666 N N . ILE A 1 354 ? -116.463 22.889 292.851 1.00 19.97 ? 354 ILE A N 1 ATOM 2667 C CA . ILE A 1 354 ? -117.555 23.442 293.636 1.00 21.50 ? 354 ILE A CA 1 ATOM 2668 C C . ILE A 1 354 ? -118.354 22.298 294.242 1.00 21.97 ? 354 ILE A C 1 ATOM 2669 O O . ILE A 1 354 ? -118.291 21.152 293.790 1.00 23.70 ? 354 ILE A O 1 ATOM 2670 C CB . ILE A 1 354 ? -118.470 24.352 292.794 1.00 26.99 ? 354 ILE A CB 1 ATOM 2671 C CG1 . ILE A 1 354 ? -119.271 23.516 291.795 1.00 25.15 ? 354 ILE A CG1 1 ATOM 2672 C CG2 . ILE A 1 354 ? -117.644 25.390 292.059 1.00 27.68 ? 354 ILE A CG2 1 ATOM 2673 C CD1 . ILE A 1 354 ? -120.406 24.270 291.142 1.00 38.81 ? 354 ILE A CD1 1 ATOM 2674 N N . SER A 1 355 ? -119.113 22.624 295.281 1.00 23.98 ? 355 SER A N 1 ATOM 2675 C CA . SER A 1 355 ? -119.977 21.641 295.911 1.00 23.46 ? 355 SER A CA 1 ATOM 2676 C C . SER A 1 355 ? -121.211 21.389 295.055 1.00 23.24 ? 355 SER A C 1 ATOM 2677 O O . SER A 1 355 ? -121.638 22.243 294.273 1.00 26.47 ? 355 SER A O 1 ATOM 2678 C CB . SER A 1 355 ? -120.401 22.105 297.303 1.00 23.94 ? 355 SER A CB 1 ATOM 2679 O OG . SER A 1 355 ? -121.132 21.089 297.965 1.00 24.42 ? 355 SER A OG 1 ATOM 2680 N N . ALA A 1 356 ? -121.781 20.196 295.209 1.00 22.04 ? 356 ALA A N 1 ATOM 2681 C CA . ALA A 1 356 ? -123.006 19.823 294.517 1.00 21.83 ? 356 ALA A CA 1 ATOM 2682 C C . ALA A 1 356 ? -124.244 20.032 295.377 1.00 23.02 ? 356 ALA A C 1 ATOM 2683 O O . ALA A 1 356 ? -125.323 19.548 295.022 1.00 24.77 ? 356 ALA A O 1 ATOM 2684 C CB . ALA A 1 356 ? -122.929 18.369 294.052 1.00 23.06 ? 356 ALA A CB 1 ATOM 2685 N N . GLY A 1 357 ? -124.112 20.735 296.500 1.00 24.52 ? 357 GLY A N 1 ATOM 2686 C CA . GLY A 1 357 ? -125.246 21.017 297.359 1.00 25.57 ? 357 GLY A CA 1 ATOM 2687 C C . GLY A 1 357 ? -125.956 22.279 296.914 1.00 27.89 ? 357 GLY A C 1 ATOM 2688 O O . GLY A 1 357 ? -125.334 23.334 296.767 1.00 30.30 ? 357 GLY A O 1 ATOM 2689 N N . TYR A 1 358 ? -127.270 22.165 296.700 1.00 23.94 ? 358 TYR A N 1 ATOM 2690 C CA . TYR A 1 358 ? -128.046 23.304 296.221 1.00 29.49 ? 358 TYR A CA 1 ATOM 2691 C C . TYR A 1 358 ? -127.996 24.463 297.208 1.00 34.98 ? 358 TYR A C 1 ATOM 2692 O O . TYR A 1 358 ? -127.952 25.631 296.803 1.00 38.48 ? 358 TYR A O 1 ATOM 2693 C CB . TYR A 1 358 ? -129.492 22.881 295.963 1.00 26.98 ? 358 TYR A CB 1 ATOM 2694 C CG . TYR A 1 358 ? -130.272 22.562 297.218 1.00 24.41 ? 358 TYR A CG 1 ATOM 2695 C CD1 . TYR A 1 358 ? -130.198 21.306 297.804 1.00 24.69 ? 358 TYR A CD1 1 ATOM 2696 C CD2 . TYR A 1 358 ? -131.085 23.517 297.817 1.00 24.94 ? 358 TYR A CD2 1 ATOM 2697 C CE1 . TYR A 1 358 ? -130.907 21.010 298.952 1.00 23.89 ? 358 TYR A CE1 1 ATOM 2698 C CE2 . TYR A 1 358 ? -131.796 23.230 298.964 1.00 24.13 ? 358 TYR A CE2 1 ATOM 2699 C CZ . TYR A 1 358 ? -131.704 21.975 299.527 1.00 22.20 ? 358 TYR A CZ 1 ATOM 2700 O OH . TYR A 1 358 ? -132.412 21.684 300.669 1.00 26.89 ? 358 TYR A OH 1 ATOM 2701 N N . ASP A 1 359 ? -128.001 24.161 298.508 1.00 28.63 ? 359 ASP A N 1 ATOM 2702 C CA . ASP A 1 359 ? -127.889 25.206 299.518 1.00 29.32 ? 359 ASP A CA 1 ATOM 2703 C C . ASP A 1 359 ? -126.556 25.933 299.436 1.00 32.71 ? 359 ASP A C 1 ATOM 2704 O O . ASP A 1 359 ? -126.425 27.034 299.982 1.00 48.25 ? 359 ASP A O 1 ATOM 2705 C CB . ASP A 1 359 ? -128.068 24.606 300.912 1.00 29.73 ? 359 ASP A CB 1 ATOM 2706 C CG . ASP A 1 359 ? -127.045 23.531 301.215 1.00 34.06 ? 359 ASP A CG 1 ATOM 2707 O OD1 . ASP A 1 359 ? -126.658 22.801 300.278 1.00 30.29 ? 359 ASP A OD1 1 ATOM 2708 O OD2 . ASP A 1 359 ? -126.624 23.418 302.385 1.00 55.99 ? 359 ASP A OD2 1 ATOM 2709 N N . LYS A 1 360 ? -125.571 25.343 298.765 1.00 30.90 ? 360 LYS A N 1 ATOM 2710 C CA . LYS A 1 360 ? -124.241 25.916 298.620 1.00 29.04 ? 360 LYS A CA 1 ATOM 2711 C C . LYS A 1 360 ? -124.012 26.522 297.243 1.00 29.43 ? 360 LYS A C 1 ATOM 2712 O O . LYS A 1 360 ? -123.322 27.539 297.125 1.00 27.41 ? 360 LYS A O 1 ATOM 2713 C CB . LYS A 1 360 ? -123.190 24.840 298.895 1.00 31.52 ? 360 LYS A CB 1 ATOM 2714 C CG . LYS A 1 360 ? -123.609 23.886 300.003 1.00 43.85 ? 360 LYS A CG 1 ATOM 2715 C CD . LYS A 1 360 ? -122.670 22.706 300.127 1.00 35.74 ? 360 LYS A CD 1 ATOM 2716 C CE . LYS A 1 360 ? -123.116 21.766 301.235 1.00 44.75 ? 360 LYS A CE 1 ATOM 2717 N NZ . LYS A 1 360 ? -122.316 20.511 301.253 1.00 43.87 ? 360 LYS A NZ 1 ATOM 2718 N N . ILE A 1 361 ? -124.583 25.917 296.199 1.00 30.02 ? 361 ILE A N 1 ATOM 2719 C CA . ILE A 1 361 ? -124.503 26.491 294.860 1.00 28.29 ? 361 ILE A CA 1 ATOM 2720 C C . ILE A 1 361 ? -125.225 27.829 294.805 1.00 30.21 ? 361 ILE A C 1 ATOM 2721 O O . ILE A 1 361 ? -124.808 28.740 294.080 1.00 41.21 ? 361 ILE A O 1 ATOM 2722 C CB . ILE A 1 361 ? -125.068 25.497 293.825 1.00 22.27 ? 361 ILE A CB 1 ATOM 2723 C CG1 . ILE A 1 361 ? -124.279 24.188 293.854 1.00 23.68 ? 361 ILE A CG1 1 ATOM 2724 C CG2 . ILE A 1 361 ? -125.047 26.096 292.429 1.00 22.47 ? 361 ILE A CG2 1 ATOM 2725 C CD1 . ILE A 1 361 ? -124.741 23.179 292.828 1.00 24.72 ? 361 ILE A CD1 1 ATOM 2726 N N . ALA A 1 362 ? -126.307 27.979 295.573 1.00 28.51 ? 362 ALA A N 1 ATOM 2727 C CA . ALA A 1 362 ? -127.059 29.228 295.573 1.00 50.98 ? 362 ALA A CA 1 ATOM 2728 C C . ALA A 1 362 ? -126.255 30.397 296.127 1.00 31.63 ? 362 ALA A C 1 ATOM 2729 O O . ALA A 1 362 ? -126.583 31.551 295.833 1.00 34.68 ? 362 ALA A O 1 ATOM 2730 C CB . ALA A 1 362 ? -128.350 29.064 296.375 1.00 33.43 ? 362 ALA A CB 1 ATOM 2731 N N . VAL A 1 363 ? -125.212 30.129 296.916 1.00 23.65 ? 363 VAL A N 1 ATOM 2732 C CA . VAL A 1 363 ? -124.425 31.213 297.494 1.00 27.72 ? 363 VAL A CA 1 ATOM 2733 C C . VAL A 1 363 ? -123.620 31.927 296.415 1.00 30.45 ? 363 VAL A C 1 ATOM 2734 O O . VAL A 1 363 ? -123.556 33.161 296.382 1.00 31.02 ? 363 VAL A O 1 ATOM 2735 C CB . VAL A 1 363 ? -123.517 30.674 298.614 1.00 28.39 ? 363 VAL A CB 1 ATOM 2736 C CG1 . VAL A 1 363 ? -122.662 31.793 299.191 1.00 26.44 ? 363 VAL A CG1 1 ATOM 2737 C CG2 . VAL A 1 363 ? -124.352 30.022 299.704 1.00 37.41 ? 363 VAL A CG2 1 ATOM 2738 N N . VAL A 1 364 ? -123.002 31.168 295.515 1.00 26.45 ? 364 VAL A N 1 ATOM 2739 C CA . VAL A 1 364 ? -122.143 31.715 294.472 1.00 23.45 ? 364 VAL A CA 1 ATOM 2740 C C . VAL A 1 364 ? -122.933 31.800 293.175 1.00 21.98 ? 364 VAL A C 1 ATOM 2741 O O . VAL A 1 364 ? -123.605 30.839 292.783 1.00 26.34 ? 364 VAL A O 1 ATOM 2742 C CB . VAL A 1 364 ? -120.880 30.858 294.287 1.00 27.52 ? 364 VAL A CB 1 ATOM 2743 C CG1 . VAL A 1 364 ? -120.022 31.414 293.165 1.00 39.43 ? 364 VAL A CG1 1 ATOM 2744 C CG2 . VAL A 1 364 ? -120.095 30.787 295.584 1.00 35.50 ? 364 VAL A CG2 1 ATOM 2745 N N . ASN A 1 365 ? -122.850 32.946 292.506 1.00 19.99 ? 365 ASN A N 1 ATOM 2746 C CA . ASN A 1 365 ? -123.477 33.131 291.199 1.00 23.65 ? 365 ASN A CA 1 ATOM 2747 C C . ASN A 1 365 ? -122.445 32.777 290.138 1.00 22.75 ? 365 ASN A C 1 ATOM 2748 O O . ASN A 1 365 ? -121.564 33.580 289.817 1.00 22.35 ? 365 ASN A O 1 ATOM 2749 C CB . ASN A 1 365 ? -123.986 34.559 291.038 1.00 33.55 ? 365 ASN A CB 1 ATOM 2750 C CG . ASN A 1 365 ? -124.386 34.877 289.610 1.00 26.64 ? 365 ASN A CG 1 ATOM 2751 O OD1 . ASN A 1 365 ? -124.930 34.030 288.902 1.00 44.54 ? 365 ASN A OD1 1 ATOM 2752 N ND2 . ASN A 1 365 ? -124.116 36.104 289.179 1.00 25.13 ? 365 ASN A ND2 1 ATOM 2753 N N . TYR A 1 366 ? -122.551 31.570 289.588 1.00 22.91 ? 366 TYR A N 1 ATOM 2754 C CA . TYR A 1 366 ? -121.570 31.081 288.629 1.00 23.91 ? 366 TYR A CA 1 ATOM 2755 C C . TYR A 1 366 ? -121.801 31.598 287.216 1.00 25.25 ? 366 TYR A C 1 ATOM 2756 O O . TYR A 1 366 ? -121.000 31.291 286.327 1.00 26.07 ? 366 TYR A O 1 ATOM 2757 C CB . TYR A 1 366 ? -121.556 29.551 288.629 1.00 24.98 ? 366 TYR A CB 1 ATOM 2758 C CG . TYR A 1 366 ? -121.230 28.959 289.979 1.00 25.55 ? 366 TYR A CG 1 ATOM 2759 C CD1 . TYR A 1 366 ? -119.915 28.726 290.353 1.00 24.07 ? 366 TYR A CD1 1 ATOM 2760 C CD2 . TYR A 1 366 ? -122.235 28.635 290.879 1.00 25.21 ? 366 TYR A CD2 1 ATOM 2761 C CE1 . TYR A 1 366 ? -119.609 28.189 291.586 1.00 26.19 ? 366 TYR A CE1 1 ATOM 2762 C CE2 . TYR A 1 366 ? -121.939 28.095 292.115 1.00 26.50 ? 366 TYR A CE2 1 ATOM 2763 C CZ . TYR A 1 366 ? -120.624 27.873 292.462 1.00 29.62 ? 366 TYR A CZ 1 ATOM 2764 O OH . TYR A 1 366 ? -120.321 27.335 293.692 1.00 32.84 ? 366 TYR A OH 1 ATOM 2765 N N . ALA A 1 367 ? -122.868 32.365 286.980 1.00 24.01 ? 367 ALA A N 1 ATOM 2766 C CA . ALA A 1 367 ? -123.010 33.033 285.692 1.00 22.66 ? 367 ALA A CA 1 ATOM 2767 C C . ALA A 1 367 ? -121.912 34.067 285.489 1.00 21.76 ? 367 ALA A C 1 ATOM 2768 O O . ALA A 1 367 ? -121.454 34.276 284.359 1.00 22.11 ? 367 ALA A O 1 ATOM 2769 C CB . ALA A 1 367 ? -124.386 33.688 285.585 1.00 24.16 ? 367 ALA A CB 1 ATOM 2770 N N . GLU A 1 368 ? -121.479 34.718 286.567 1.00 20.53 ? 368 GLU A N 1 ATOM 2771 C CA . GLU A 1 368 ? -120.357 35.643 286.519 1.00 21.58 ? 368 GLU A CA 1 ATOM 2772 C C . GLU A 1 368 ? -119.018 34.938 286.676 1.00 23.91 ? 368 GLU A C 1 ATOM 2773 O O . GLU A 1 368 ? -118.019 35.381 286.098 1.00 29.99 ? 368 GLU A O 1 ATOM 2774 C CB . GLU A 1 368 ? -120.508 36.706 287.612 1.00 22.66 ? 368 GLU A CB 1 ATOM 2775 C CG . GLU A 1 368 ? -119.448 37.795 287.591 1.00 25.18 ? 368 GLU A CG 1 ATOM 2776 C CD . GLU A 1 368 ? -119.715 38.852 286.540 1.00 26.37 ? 368 GLU A CD 1 ATOM 2777 O OE1 . GLU A 1 368 ? -120.795 38.813 285.915 1.00 20.76 ? 368 GLU A OE1 1 ATOM 2778 O OE2 . GLU A 1 368 ? -118.846 39.727 286.342 1.00 21.25 ? 368 GLU A OE2 1 ATOM 2779 N N . ALA A 1 369 ? -118.980 33.842 287.438 1.00 22.75 ? 369 ALA A N 1 ATOM 2780 C CA . ALA A 1 369 ? -117.724 33.134 287.653 1.00 24.19 ? 369 ALA A CA 1 ATOM 2781 C C . ALA A 1 369 ? -117.300 32.341 286.424 1.00 26.65 ? 369 ALA A C 1 ATOM 2782 O O . ALA A 1 369 ? -116.105 32.089 286.235 1.00 33.60 ? 369 ALA A O 1 ATOM 2783 C CB . ALA A 1 369 ? -117.843 32.207 288.862 1.00 24.18 ? 369 ALA A CB 1 ATOM 2784 N N . GLN A 1 370 ? -118.254 31.942 285.579 1.00 25.82 ? 370 GLN A N 1 ATOM 2785 C CA . GLN A 1 370 ? -117.918 31.109 284.431 1.00 30.26 ? 370 GLN A CA 1 ATOM 2786 C C . GLN A 1 370 ? -117.145 31.868 283.361 1.00 35.62 ? 370 GLN A C 1 ATOM 2787 O O . GLN A 1 370 ? -116.510 31.235 282.512 1.00 31.81 ? 370 GLN A O 1 ATOM 2788 C CB . GLN A 1 370 ? -119.183 30.505 283.820 1.00 33.05 ? 370 GLN A CB 1 ATOM 2789 C CG . GLN A 1 370 ? -120.023 31.486 283.025 1.00 29.45 ? 370 GLN A CG 1 ATOM 2790 C CD . GLN A 1 370 ? -121.161 30.808 282.290 1.00 36.24 ? 370 GLN A CD 1 ATOM 2791 O OE1 . GLN A 1 370 ? -121.204 29.582 282.187 1.00 34.37 ? 370 GLN A OE1 1 ATOM 2792 N NE2 . GLN A 1 370 ? -122.088 31.603 281.773 1.00 54.59 ? 370 GLN A NE2 1 ATOM 2793 N N . LYS A 1 371 ? -117.184 33.200 283.371 1.00 29.97 ? 371 LYS A N 1 ATOM 2794 C CA . LYS A 1 371 ? -116.385 33.961 282.421 1.00 33.05 ? 371 LYS A CA 1 ATOM 2795 C C . LYS A 1 371 ? -114.931 34.087 282.861 1.00 31.84 ? 371 LYS A C 1 ATOM 2796 O O . LYS A 1 371 ? -114.106 34.598 282.096 1.00 35.15 ? 371 LYS A O 1 ATOM 2797 C CB . LYS A 1 371 ? -117.007 35.344 282.200 1.00 42.29 ? 371 LYS A CB 1 ATOM 2798 C CG . LYS A 1 371 ? -116.560 36.029 280.915 1.00 74.73 ? 371 LYS A CG 1 ATOM 2799 C CD . LYS A 1 371 ? -117.686 36.831 280.286 1.00 83.11 ? 371 LYS A CD 1 ATOM 2800 C CE . LYS A 1 371 ? -118.582 35.940 279.440 1.00 73.20 ? 371 LYS A CE 1 ATOM 2801 N NZ . LYS A 1 371 ? -117.798 35.102 278.489 1.00 55.65 ? 371 LYS A NZ 1 ATOM 2802 N N . SER A 1 372 ? -114.601 33.627 284.069 1.00 29.03 ? 372 SER A N 1 ATOM 2803 C CA . SER A 1 372 ? -113.220 33.486 284.501 1.00 47.24 ? 372 SER A CA 1 ATOM 2804 C C . SER A 1 372 ? -112.775 32.036 284.616 1.00 33.28 ? 372 SER A C 1 ATOM 2805 O O . SER A 1 372 ? -111.574 31.766 284.525 1.00 28.58 ? 372 SER A O 1 ATOM 2806 C CB . SER A 1 372 ? -113.006 34.182 285.853 1.00 32.89 ? 372 SER A CB 1 ATOM 2807 O OG . SER A 1 372 ? -113.315 35.562 285.768 1.00 27.97 ? 372 SER A OG 1 ATOM 2808 N N . LEU A 1 373 ? -113.707 31.106 284.808 1.00 28.37 ? 373 LEU A N 1 ATOM 2809 C CA . LEU A 1 373 ? -113.393 29.687 284.871 1.00 26.27 ? 373 LEU A CA 1 ATOM 2810 C C . LEU A 1 373 ? -113.544 29.052 283.497 1.00 25.04 ? 373 LEU A C 1 ATOM 2811 O O . LEU A 1 373 ? -114.479 29.364 282.754 1.00 26.77 ? 373 LEU A O 1 ATOM 2812 C CB . LEU A 1 373 ? -114.304 28.976 285.872 1.00 32.27 ? 373 LEU A CB 1 ATOM 2813 C CG . LEU A 1 373 ? -114.178 29.388 287.338 1.00 29.90 ? 373 LEU A CG 1 ATOM 2814 C CD1 . LEU A 1 373 ? -115.182 28.630 288.190 1.00 24.09 ? 373 LEU A CD1 1 ATOM 2815 C CD2 . LEU A 1 373 ? -112.762 29.142 287.831 1.00 27.47 ? 373 LEU A CD2 1 ATOM 2816 N N . GLY A 1 374 ? -112.617 28.161 283.162 1.00 29.20 ? 374 GLY A N 1 ATOM 2817 C CA . GLY A 1 374 ? -112.710 27.423 281.920 1.00 32.19 ? 374 GLY A CA 1 ATOM 2818 C C . GLY A 1 374 ? -113.525 26.159 282.087 1.00 29.73 ? 374 GLY A C 1 ATOM 2819 O O . GLY A 1 374 ? -114.211 25.719 281.160 1.00 41.73 ? 374 GLY A O 1 ATOM 2820 N N . LYS A 1 375 ? -113.456 25.570 283.279 1.00 30.01 ? 375 LYS A N 1 ATOM 2821 C CA . LYS A 1 375 ? -114.191 24.357 283.599 1.00 34.10 ? 375 LYS A CA 1 ATOM 2822 C C . LYS A 1 375 ? -114.606 24.409 285.061 1.00 32.06 ? 375 LYS A C 1 ATOM 2823 O O . LYS A 1 375 ? -113.971 25.082 285.877 1.00 29.96 ? 375 LYS A O 1 ATOM 2824 C CB . LYS A 1 375 ? -113.355 23.099 283.327 1.00 31.49 ? 375 LYS A CB 1 ATOM 2825 C CG . LYS A 1 375 ? -113.174 22.776 281.853 1.00 36.03 ? 375 LYS A CG 1 ATOM 2826 C CD . LYS A 1 375 ? -112.141 21.685 281.647 1.00 43.21 ? 375 LYS A CD 1 ATOM 2827 C CE . LYS A 1 375 ? -110.744 22.273 281.547 1.00 50.50 ? 375 LYS A CE 1 ATOM 2828 N NZ . LYS A 1 375 ? -110.638 23.267 280.444 1.00 48.15 ? 375 LYS A NZ 1 ATOM 2829 N N . ILE A 1 376 ? -115.679 23.691 285.384 1.00 30.58 ? 376 ILE A N 1 ATOM 2830 C CA . ILE A 1 376 ? -116.209 23.627 286.741 1.00 27.79 ? 376 ILE A CA 1 ATOM 2831 C C . ILE A 1 376 ? -116.293 22.164 287.146 1.00 26.11 ? 376 ILE A C 1 ATOM 2832 O O . ILE A 1 376 ? -117.018 21.383 286.517 1.00 25.39 ? 376 ILE A O 1 ATOM 2833 C CB . ILE A 1 376 ? -117.588 24.298 286.856 1.00 27.33 ? 376 ILE A CB 1 ATOM 2834 C CG1 . ILE A 1 376 ? -117.481 25.793 286.548 1.00 31.87 ? 376 ILE A CG1 1 ATOM 2835 C CG2 . ILE A 1 376 ? -118.171 24.075 288.240 1.00 23.55 ? 376 ILE A CG2 1 ATOM 2836 C CD1 . ILE A 1 376 ? -118.799 26.529 286.634 1.00 30.33 ? 376 ILE A CD1 1 ATOM 2837 N N . PHE A 1 377 ? -115.558 21.793 288.191 1.00 22.08 ? 377 PHE A N 1 ATOM 2838 C CA . PHE A 1 377 ? -115.550 20.421 288.694 1.00 22.26 ? 377 PHE A CA 1 ATOM 2839 C C . PHE A 1 377 ? -116.645 20.290 289.745 1.00 26.85 ? 377 PHE A C 1 ATOM 2840 O O . PHE A 1 377 ? -116.451 20.640 290.911 1.00 39.26 ? 377 PHE A O 1 ATOM 2841 C CB . PHE A 1 377 ? -114.181 20.061 289.262 1.00 23.00 ? 377 PHE A CB 1 ATOM 2842 C CG . PHE A 1 377 ? -113.083 20.063 288.239 1.00 22.21 ? 377 PHE A CG 1 ATOM 2843 C CD1 . PHE A 1 377 ? -113.079 19.140 287.206 1.00 22.12 ? 377 PHE A CD1 1 ATOM 2844 C CD2 . PHE A 1 377 ? -112.052 20.984 288.311 1.00 23.04 ? 377 PHE A CD2 1 ATOM 2845 C CE1 . PHE A 1 377 ? -112.070 19.138 286.263 1.00 24.73 ? 377 PHE A CE1 1 ATOM 2846 C CE2 . PHE A 1 377 ? -111.040 20.985 287.371 1.00 27.50 ? 377 PHE A CE2 1 ATOM 2847 C CZ . PHE A 1 377 ? -111.049 20.062 286.346 1.00 31.23 ? 377 PHE A CZ 1 ATOM 2848 N N . LEU A 1 378 ? -117.803 19.782 289.330 1.00 25.72 ? 378 LEU A N 1 ATOM 2849 C CA . LEU A 1 378 ? -118.942 19.618 290.227 1.00 23.90 ? 378 LEU A CA 1 ATOM 2850 C C . LEU A 1 378 ? -118.725 18.374 291.079 1.00 23.70 ? 378 LEU A C 1 ATOM 2851 O O . LEU A 1 378 ? -118.849 17.247 290.588 1.00 23.91 ? 378 LEU A O 1 ATOM 2852 C CB . LEU A 1 378 ? -120.237 19.522 289.427 1.00 23.43 ? 378 LEU A CB 1 ATOM 2853 C CG . LEU A 1 378 ? -121.526 19.336 290.227 1.00 22.65 ? 378 LEU A CG 1 ATOM 2854 C CD1 . LEU A 1 378 ? -121.763 20.530 291.133 1.00 30.68 ? 378 LEU A CD1 1 ATOM 2855 C CD2 . LEU A 1 378 ? -122.707 19.124 289.294 1.00 22.23 ? 378 LEU A CD2 1 ATOM 2856 N N . MET A 1 379 ? -118.401 18.575 292.356 1.00 22.51 ? 379 MET A N 1 ATOM 2857 C CA . MET A 1 379 ? -118.124 17.471 293.275 1.00 22.64 ? 379 MET A CA 1 ATOM 2858 C C . MET A 1 379 ? -119.438 16.778 293.624 1.00 26.28 ? 379 MET A C 1 ATOM 2859 O O . MET A 1 379 ? -120.058 17.023 294.661 1.00 25.87 ? 379 MET A O 1 ATOM 2860 C CB . MET A 1 379 ? -117.411 17.977 294.523 1.00 19.83 ? 379 MET A CB 1 ATOM 2861 C CG . MET A 1 379 ? -115.990 18.450 294.274 1.00 16.47 ? 379 MET A CG 1 ATOM 2862 S SD . MET A 1 379 ? -115.176 19.034 295.771 1.00 12.18 ? 379 MET A SD 1 ATOM 2863 C CE . MET A 1 379 ? -116.274 20.355 296.270 1.00 26.88 ? 379 MET A CE 1 ATOM 2864 N N . SER A 1 380 ? -119.864 15.886 292.733 1.00 25.79 ? 380 SER A N 1 ATOM 2865 C CA . SER A 1 380 ? -121.121 15.157 292.902 1.00 23.72 ? 380 SER A CA 1 ATOM 2866 C C . SER A 1 380 ? -120.896 13.874 293.706 1.00 24.68 ? 380 SER A C 1 ATOM 2867 O O . SER A 1 380 ? -121.111 12.757 293.236 1.00 22.93 ? 380 SER A O 1 ATOM 2868 C CB . SER A 1 380 ? -121.744 14.859 291.544 1.00 25.97 ? 380 SER A CB 1 ATOM 2869 O OG . SER A 1 380 ? -120.876 14.071 290.749 1.00 23.26 ? 380 SER A OG 1 ATOM 2870 N N . TYR A 1 381 ? -120.451 14.060 294.944 1.00 29.32 ? 381 TYR A N 1 ATOM 2871 C CA . TYR A 1 381 ? -120.258 12.954 295.873 1.00 27.88 ? 381 TYR A CA 1 ATOM 2872 C C . TYR A 1 381 ? -120.298 13.510 297.291 1.00 27.45 ? 381 TYR A C 1 ATOM 2873 O O . TYR A 1 381 ? -120.500 14.709 297.503 1.00 43.62 ? 381 TYR A O 1 ATOM 2874 C CB . TYR A 1 381 ? -118.951 12.204 295.589 1.00 25.31 ? 381 TYR A CB 1 ATOM 2875 C CG . TYR A 1 381 ? -117.771 13.093 295.266 1.00 23.23 ? 381 TYR A CG 1 ATOM 2876 C CD1 . TYR A 1 381 ? -117.005 13.661 296.275 1.00 22.36 ? 381 TYR A CD1 1 ATOM 2877 C CD2 . TYR A 1 381 ? -117.416 13.354 293.949 1.00 22.93 ? 381 TYR A CD2 1 ATOM 2878 C CE1 . TYR A 1 381 ? -115.923 14.470 295.982 1.00 22.18 ? 381 TYR A CE1 1 ATOM 2879 C CE2 . TYR A 1 381 ? -116.337 14.162 293.646 1.00 22.66 ? 381 TYR A CE2 1 ATOM 2880 C CZ . TYR A 1 381 ? -115.594 14.716 294.665 1.00 21.01 ? 381 TYR A CZ 1 ATOM 2881 O OH . TYR A 1 381 ? -114.519 15.520 294.366 1.00 17.94 ? 381 TYR A OH 1 ATOM 2882 N N . ASP A 1 382 ? -120.111 12.617 298.264 1.00 25.56 ? 382 ASP A N 1 ATOM 2883 C CA . ASP A 1 382 ? -120.163 12.959 299.686 1.00 24.16 ? 382 ASP A CA 1 ATOM 2884 C C . ASP A 1 382 ? -121.522 13.528 300.080 1.00 29.34 ? 382 ASP A C 1 ATOM 2885 O O . ASP A 1 382 ? -121.623 14.346 300.998 1.00 40.79 ? 382 ASP A O 1 ATOM 2886 C CB . ASP A 1 382 ? -119.042 13.930 300.068 1.00 26.17 ? 382 ASP A CB 1 ATOM 2887 C CG . ASP A 1 382 ? -117.667 13.323 299.895 1.00 38.43 ? 382 ASP A CG 1 ATOM 2888 O OD1 . ASP A 1 382 ? -117.554 12.082 299.972 1.00 43.92 ? 382 ASP A OD1 1 ATOM 2889 O OD2 . ASP A 1 382 ? -116.699 14.081 299.678 1.00 32.32 ? 382 ASP A OD2 1 ATOM 2890 N N . PHE A 1 383 ? -122.579 13.099 299.386 1.00 29.69 ? 383 PHE A N 1 ATOM 2891 C CA . PHE A 1 383 ? -123.926 13.525 299.750 1.00 30.88 ? 383 PHE A CA 1 ATOM 2892 C C . PHE A 1 383 ? -124.336 12.947 301.098 1.00 30.50 ? 383 PHE A C 1 ATOM 2893 O O . PHE A 1 383 ? -124.936 13.644 301.925 1.00 26.13 ? 383 PHE A O 1 ATOM 2894 C CB . PHE A 1 383 ? -124.919 13.108 298.666 1.00 33.43 ? 383 PHE A CB 1 ATOM 2895 C CG . PHE A 1 383 ? -124.714 13.807 297.353 1.00 29.93 ? 383 PHE A CG 1 ATOM 2896 C CD1 . PHE A 1 383 ? -124.352 15.142 297.312 1.00 29.81 ? 383 PHE A CD1 1 ATOM 2897 C CD2 . PHE A 1 383 ? -124.875 13.125 296.158 1.00 32.01 ? 383 PHE A CD2 1 ATOM 2898 C CE1 . PHE A 1 383 ? -124.163 15.786 296.106 1.00 34.18 ? 383 PHE A CE1 1 ATOM 2899 C CE2 . PHE A 1 383 ? -124.687 13.764 294.948 1.00 31.64 ? 383 PHE A CE2 1 ATOM 2900 C CZ . PHE A 1 383 ? -124.329 15.095 294.921 1.00 28.85 ? 383 PHE A CZ 1 ATOM 2901 N N . LYS A 1 384 ? -124.026 11.675 301.334 1.00 33.12 ? 384 LYS A N 1 ATOM 2902 C CA . LYS A 1 384 ? -124.297 11.012 302.599 1.00 31.60 ? 384 LYS A CA 1 ATOM 2903 C C . LYS A 1 384 ? -123.022 10.337 303.081 1.00 32.86 ? 384 LYS A C 1 ATOM 2904 O O . LYS A 1 384 ? -122.192 9.903 302.278 1.00 32.46 ? 384 LYS A O 1 ATOM 2905 C CB . LYS A 1 384 ? -125.422 9.977 302.465 1.00 34.96 ? 384 LYS A CB 1 ATOM 2906 C CG . LYS A 1 384 ? -126.709 10.525 301.869 1.00 40.98 ? 384 LYS A CG 1 ATOM 2907 C CD . LYS A 1 384 ? -127.373 11.536 302.787 1.00 34.27 ? 384 LYS A CD 1 ATOM 2908 C CE . LYS A 1 384 ? -128.733 11.951 302.250 1.00 29.32 ? 384 LYS A CE 1 ATOM 2909 N NZ . LYS A 1 384 ? -128.658 12.409 300.835 1.00 39.81 ? 384 LYS A NZ 1 ATOM 2910 N N . GLY A 1 385 ? -122.871 10.250 304.399 1.00 30.07 ? 385 GLY A N 1 ATOM 2911 C CA . GLY A 1 385 ? -121.660 9.672 304.947 1.00 33.06 ? 385 GLY A CA 1 ATOM 2912 C C . GLY A 1 385 ? -121.877 9.135 306.344 1.00 31.88 ? 385 GLY A C 1 ATOM 2913 O O . GLY A 1 385 ? -122.976 9.199 306.900 1.00 29.72 ? 385 GLY A O 1 ATOM 2914 N N . ALA A 1 386 ? -120.795 8.601 306.908 1.00 32.17 ? 386 ALA A N 1 ATOM 2915 C CA . ALA A 1 386 ? -120.814 8.025 308.246 1.00 34.65 ? 386 ALA A CA 1 ATOM 2916 C C . ALA A 1 386 ? -120.832 9.075 309.348 1.00 35.64 ? 386 ALA A C 1 ATOM 2917 O O . ALA A 1 386 ? -120.840 8.708 310.528 1.00 41.99 ? 386 ALA A O 1 ATOM 2918 C CB . ALA A 1 386 ? -119.609 7.101 308.436 1.00 37.62 ? 386 ALA A CB 1 ATOM 2919 N N . TRP A 1 387 ? -120.833 10.363 309.001 1.00 35.38 ? 387 TRP A N 1 ATOM 2920 C CA . TRP A 1 387 ? -120.916 11.411 310.009 1.00 36.87 ? 387 TRP A CA 1 ATOM 2921 C C . TRP A 1 387 ? -122.287 11.486 310.666 1.00 35.30 ? 387 TRP A C 1 ATOM 2922 O O . TRP A 1 387 ? -122.421 12.142 311.704 1.00 48.97 ? 387 TRP A O 1 ATOM 2923 C CB . TRP A 1 387 ? -120.564 12.766 309.391 1.00 31.93 ? 387 TRP A CB 1 ATOM 2924 C CG . TRP A 1 387 ? -121.290 13.056 308.113 1.00 34.16 ? 387 TRP A CG 1 ATOM 2925 C CD1 . TRP A 1 387 ? -122.574 13.496 307.981 1.00 34.59 ? 387 TRP A CD1 1 ATOM 2926 C CD2 . TRP A 1 387 ? -120.769 12.935 306.784 1.00 32.40 ? 387 TRP A CD2 1 ATOM 2927 N NE1 . TRP A 1 387 ? -122.888 13.652 306.653 1.00 38.37 ? 387 TRP A NE1 1 ATOM 2928 C CE2 . TRP A 1 387 ? -121.796 13.314 305.897 1.00 36.08 ? 387 TRP A CE2 1 ATOM 2929 C CE3 . TRP A 1 387 ? -119.536 12.541 306.257 1.00 31.83 ? 387 TRP A CE3 1 ATOM 2930 C CZ2 . TRP A 1 387 ? -121.628 13.311 304.514 1.00 34.09 ? 387 TRP A CZ2 1 ATOM 2931 C CZ3 . TRP A 1 387 ? -119.370 12.538 304.884 1.00 31.99 ? 387 TRP A CZ3 1 ATOM 2932 C CH2 . TRP A 1 387 ? -120.410 12.920 304.028 1.00 31.41 ? 387 TRP A CH2 1 ATOM 2933 N N . SER A 1 388 ? -123.298 10.835 310.094 1.00 33.92 ? 388 SER A N 1 ATOM 2934 C CA . SER A 1 388 ? -124.641 10.821 310.661 1.00 38.27 ? 388 SER A CA 1 ATOM 2935 C C . SER A 1 388 ? -125.206 9.416 310.534 1.00 45.71 ? 388 SER A C 1 ATOM 2936 O O . SER A 1 388 ? -125.424 8.933 309.419 1.00 48.91 ? 388 SER A O 1 ATOM 2937 C CB . SER A 1 388 ? -125.552 11.831 309.958 1.00 59.13 ? 388 SER A CB 1 ATOM 2938 O OG . SER A 1 388 ? -126.880 11.745 310.446 1.00 38.45 ? 388 SER A OG 1 ATOM 2939 N N . ASN A 1 389 ? -125.439 8.763 311.674 1.00 35.83 ? 389 ASN A N 1 ATOM 2940 C CA . ASN A 1 389 ? -126.042 7.437 311.667 1.00 34.11 ? 389 ASN A CA 1 ATOM 2941 C C . ASN A 1 389 ? -127.529 7.471 311.343 1.00 32.97 ? 389 ASN A C 1 ATOM 2942 O O . ASN A 1 389 ? -128.108 6.416 311.062 1.00 33.53 ? 389 ASN A O 1 ATOM 2943 C CB . ASN A 1 389 ? -125.825 6.754 313.018 1.00 36.41 ? 389 ASN A CB 1 ATOM 2944 C CG . ASN A 1 389 ? -124.364 6.465 313.296 1.00 41.05 ? 389 ASN A CG 1 ATOM 2945 O OD1 . ASN A 1 389 ? -123.529 6.502 312.392 1.00 47.08 ? 389 ASN A OD1 1 ATOM 2946 N ND2 . ASN A 1 389 ? -124.046 6.174 314.552 1.00 48.70 ? 389 ASN A ND2 1 ATOM 2947 N N . THR A 1 390 ? -128.155 8.646 311.374 1.00 32.36 ? 390 THR A N 1 ATOM 2948 C CA . THR A 1 390 ? -129.579 8.774 311.081 1.00 32.98 ? 390 THR A CA 1 ATOM 2949 C C . THR A 1 390 ? -129.830 8.939 309.585 1.00 31.21 ? 390 THR A C 1 ATOM 2950 O O . THR A 1 390 ? -130.572 8.158 308.981 1.00 32.53 ? 390 THR A O 1 ATOM 2951 C CB . THR A 1 390 ? -130.169 9.959 311.854 1.00 30.89 ? 390 THR A CB 1 ATOM 2952 O OG1 . THR A 1 390 ? -129.521 11.170 311.443 1.00 39.85 ? 390 THR A OG1 1 ATOM 2953 C CG2 . THR A 1 390 ? -129.973 9.770 313.350 1.00 34.40 ? 390 THR A CG2 1 ATOM 2954 N N . ASP A 1 391 ? -129.214 9.952 308.976 1.00 33.65 ? 391 ASP A N 1 ATOM 2955 C CA . ASP A 1 391 ? -129.429 10.261 307.563 1.00 35.93 ? 391 ASP A CA 1 ATOM 2956 C C . ASP A 1 391 ? -128.637 9.269 306.715 1.00 33.28 ? 391 ASP A C 1 ATOM 2957 O O . ASP A 1 391 ? -127.527 9.537 306.248 1.00 37.22 ? 391 ASP A O 1 ATOM 2958 C CB . ASP A 1 391 ? -129.033 11.701 307.264 1.00 47.25 ? 391 ASP A CB 1 ATOM 2959 C CG . ASP A 1 391 ? -129.316 12.099 305.827 1.00 33.22 ? 391 ASP A CG 1 ATOM 2960 O OD1 . ASP A 1 391 ? -130.084 11.385 305.149 1.00 30.63 ? 391 ASP A OD1 1 ATOM 2961 O OD2 . ASP A 1 391 ? -128.770 13.128 305.376 1.00 32.65 ? 391 ASP A OD2 1 ATOM 2962 N N . LEU A 1 392 ? -129.229 8.095 306.516 1.00 29.71 ? 392 LEU A N 1 ATOM 2963 C CA . LEU A 1 392 ? -128.661 7.089 305.632 1.00 30.31 ? 392 LEU A CA 1 ATOM 2964 C C . LEU A 1 392 ? -129.158 7.313 304.210 1.00 35.15 ? 392 LEU A C 1 ATOM 2965 O O . LEU A 1 392 ? -130.339 7.595 303.989 1.00 37.34 ? 392 LEU A O 1 ATOM 2966 C CB . LEU A 1 392 ? -129.028 5.679 306.098 1.00 34.77 ? 392 LEU A CB 1 ATOM 2967 C CG . LEU A 1 392 ? -128.673 5.292 307.535 1.00 31.89 ? 392 LEU A CG 1 ATOM 2968 C CD1 . LEU A 1 392 ? -128.884 3.802 307.752 1.00 33.86 ? 392 LEU A CD1 1 ATOM 2969 C CD2 . LEU A 1 392 ? -127.242 5.684 307.864 1.00 32.40 ? 392 LEU A CD2 1 ATOM 2970 N N . GLY A 1 393 ? -128.251 7.190 303.251 1.00 33.13 ? 393 GLY A N 1 ATOM 2971 C CA . GLY A 1 393 ? -128.618 7.394 301.864 1.00 31.18 ? 393 GLY A CA 1 ATOM 2972 C C . GLY A 1 393 ? -127.446 7.119 300.951 1.00 32.42 ? 393 GLY A C 1 ATOM 2973 O O . GLY A 1 393 ? -126.436 6.542 301.359 1.00 40.75 ? 393 GLY A O 1 ATOM 2974 N N . TYR A 1 394 ? -127.597 7.544 299.700 1.00 33.09 ? 394 TYR A N 1 ATOM 2975 C CA . TYR A 1 394 ? -126.558 7.345 298.699 1.00 30.14 ? 394 TYR A CA 1 ATOM 2976 C C . TYR A 1 394 ? -125.511 8.447 298.805 1.00 31.04 ? 394 TYR A C 1 ATOM 2977 O O . TYR A 1 394 ? -125.840 9.636 298.755 1.00 42.60 ? 394 TYR A O 1 ATOM 2978 C CB . TYR A 1 394 ? -127.161 7.324 297.295 1.00 29.10 ? 394 TYR A CB 1 ATOM 2979 C CG . TYR A 1 394 ? -128.089 6.158 297.028 1.00 34.20 ? 394 TYR A CG 1 ATOM 2980 C CD1 . TYR A 1 394 ? -128.110 5.050 297.867 1.00 34.10 ? 394 TYR A CD1 1 ATOM 2981 C CD2 . TYR A 1 394 ? -128.942 6.164 295.932 1.00 30.61 ? 394 TYR A CD2 1 ATOM 2982 C CE1 . TYR A 1 394 ? -128.956 3.985 297.623 1.00 30.82 ? 394 TYR A CE1 1 ATOM 2983 C CE2 . TYR A 1 394 ? -129.791 5.103 295.680 1.00 28.19 ? 394 TYR A CE2 1 ATOM 2984 C CZ . TYR A 1 394 ? -129.793 4.017 296.529 1.00 28.67 ? 394 TYR A CZ 1 ATOM 2985 O OH . TYR A 1 394 ? -130.637 2.958 296.281 1.00 28.63 ? 394 TYR A OH 1 ATOM 2986 N N . GLN A 1 395 ? -124.246 8.046 298.955 1.00 33.57 ? 395 GLN A N 1 ATOM 2987 C CA . GLN A 1 395 ? -123.161 9.021 298.991 1.00 29.34 ? 395 GLN A CA 1 ATOM 2988 C C . GLN A 1 395 ? -123.032 9.746 297.658 1.00 37.20 ? 395 GLN A C 1 ATOM 2989 O O . GLN A 1 395 ? -122.803 10.960 297.620 1.00 38.97 ? 395 GLN A O 1 ATOM 2990 C CB . GLN A 1 395 ? -121.850 8.327 299.359 1.00 29.52 ? 395 GLN A CB 1 ATOM 2991 C CG . GLN A 1 395 ? -120.607 9.004 298.810 1.00 32.10 ? 395 GLN A CG 1 ATOM 2992 C CD . GLN A 1 395 ? -119.438 8.050 298.679 1.00 44.49 ? 395 GLN A CD 1 ATOM 2993 O OE1 . GLN A 1 395 ? -119.178 7.243 299.570 1.00 57.15 ? 395 GLN A OE1 1 ATOM 2994 N NE2 . GLN A 1 395 ? -118.726 8.139 297.563 1.00 48.02 ? 395 GLN A NE2 1 ATOM 2995 N N . THR A 1 396 ? -123.180 9.018 296.554 1.00 32.99 ? 396 THR A N 1 ATOM 2996 C CA . THR A 1 396 ? -123.157 9.601 295.222 1.00 27.63 ? 396 THR A CA 1 ATOM 2997 C C . THR A 1 396 ? -124.213 8.922 294.364 1.00 26.80 ? 396 THR A C 1 ATOM 2998 O O . THR A 1 396 ? -124.392 7.702 294.434 1.00 29.34 ? 396 THR A O 1 ATOM 2999 C CB . THR A 1 396 ? -121.774 9.469 294.569 1.00 28.72 ? 396 THR A CB 1 ATOM 3000 O OG1 . THR A 1 396 ? -121.853 9.860 293.192 1.00 27.03 ? 396 THR A OG1 1 ATOM 3001 C CG2 . THR A 1 396 ? -121.263 8.039 294.665 1.00 27.36 ? 396 THR A CG2 1 ATOM 3002 N N . THR A 1 397 ? -124.914 9.719 293.564 1.00 26.52 ? 397 THR A N 1 ATOM 3003 C CA . THR A 1 397 ? -125.993 9.216 292.724 1.00 26.32 ? 397 THR A CA 1 ATOM 3004 C C . THR A 1 397 ? -126.331 10.272 291.685 1.00 27.37 ? 397 THR A C 1 ATOM 3005 O O . THR A 1 397 ? -126.089 11.465 291.886 1.00 27.82 ? 397 THR A O 1 ATOM 3006 C CB . THR A 1 397 ? -127.237 8.866 293.548 1.00 25.16 ? 397 THR A CB 1 ATOM 3007 O OG1 . THR A 1 397 ? -128.333 8.590 292.667 1.00 28.87 ? 397 THR A OG1 1 ATOM 3008 C CG2 . THR A 1 397 ? -127.610 10.019 294.464 1.00 28.27 ? 397 THR A CG2 1 ATOM 3009 N N . VAL A 1 398 ? -126.898 9.816 290.570 1.00 26.65 ? 398 VAL A N 1 ATOM 3010 C CA . VAL A 1 398 ? -127.353 10.736 289.531 1.00 28.47 ? 398 VAL A CA 1 ATOM 3011 C C . VAL A 1 398 ? -128.734 11.280 289.868 1.00 38.93 ? 398 VAL A C 1 ATOM 3012 O O . VAL A 1 398 ? -128.937 12.496 289.962 1.00 42.40 ? 398 VAL A O 1 ATOM 3013 C CB . VAL A 1 398 ? -127.345 10.044 288.157 1.00 26.91 ? 398 VAL A CB 1 ATOM 3014 C CG1 . VAL A 1 398 ? -127.721 11.034 287.066 1.00 31.78 ? 398 VAL A CG1 1 ATOM 3015 C CG2 . VAL A 1 398 ? -125.985 9.438 287.882 1.00 38.92 ? 398 VAL A CG2 1 ATOM 3016 N N . TYR A 1 399 ? -129.699 10.389 290.060 1.00 33.97 ? 399 TYR A N 1 ATOM 3017 C CA . TYR A 1 399 ? -131.074 10.757 290.360 1.00 33.47 ? 399 TYR A CA 1 ATOM 3018 C C . TYR A 1 399 ? -131.408 10.386 291.802 1.00 30.20 ? 399 TYR A C 1 ATOM 3019 O O . TYR A 1 399 ? -130.568 9.882 292.554 1.00 29.00 ? 399 TYR A O 1 ATOM 3020 C CB . TYR A 1 399 ? -132.033 10.085 289.375 1.00 39.62 ? 399 TYR A CB 1 ATOM 3021 C CG . TYR A 1 399 ? -131.771 10.452 287.932 1.00 33.10 ? 399 TYR A CG 1 ATOM 3022 C CD1 . TYR A 1 399 ? -132.141 11.693 287.433 1.00 33.34 ? 399 TYR A CD1 1 ATOM 3023 C CD2 . TYR A 1 399 ? -131.152 9.557 287.070 1.00 33.35 ? 399 TYR A CD2 1 ATOM 3024 C CE1 . TYR A 1 399 ? -131.902 12.033 286.115 1.00 36.00 ? 399 TYR A CE1 1 ATOM 3025 C CE2 . TYR A 1 399 ? -130.910 9.888 285.750 1.00 36.74 ? 399 TYR A CE2 1 ATOM 3026 C CZ . TYR A 1 399 ? -131.285 11.127 285.278 1.00 39.19 ? 399 TYR A CZ 1 ATOM 3027 O OH . TYR A 1 399 ? -131.047 11.460 283.965 1.00 38.13 ? 399 TYR A OH 1 ATOM 3028 N N . ALA A 1 400 ? -132.656 10.643 292.183 1.00 27.47 ? 400 ALA A N 1 ATOM 3029 C CA . ALA A 1 400 ? -133.108 10.388 293.540 1.00 25.55 ? 400 ALA A CA 1 ATOM 3030 C C . ALA A 1 400 ? -133.335 8.894 293.763 1.00 25.43 ? 400 ALA A C 1 ATOM 3031 O O . ALA A 1 400 ? -133.735 8.176 292.842 1.00 24.70 ? 400 ALA A O 1 ATOM 3032 C CB . ALA A 1 400 ? -134.396 11.153 293.822 1.00 34.25 ? 400 ALA A CB 1 ATOM 3033 N N . PRO A 1 401 ? -133.088 8.405 294.979 1.00 26.41 ? 401 PRO A N 1 ATOM 3034 C CA . PRO A 1 401 ? -133.226 6.968 295.245 1.00 31.90 ? 401 PRO A CA 1 ATOM 3035 C C . PRO A 1 401 ? -134.642 6.469 294.996 1.00 46.25 ? 401 PRO A C 1 ATOM 3036 O O . PRO A 1 401 ? -135.607 7.236 294.939 1.00 34.18 ? 401 PRO A O 1 ATOM 3037 C CB . PRO A 1 401 ? -132.850 6.844 296.727 1.00 27.52 ? 401 PRO A CB 1 ATOM 3038 C CG . PRO A 1 401 ? -132.001 8.034 297.002 1.00 25.48 ? 401 PRO A CG 1 ATOM 3039 C CD . PRO A 1 401 ? -132.552 9.132 296.143 1.00 23.44 ? 401 PRO A CD 1 ATOM 3040 N N . SER A 1 402 ? -134.755 5.147 294.844 1.00 47.37 ? 402 SER A N 1 ATOM 3041 C CA . SER A 1 402 ? -136.061 4.535 294.627 1.00 34.60 ? 402 SER A CA 1 ATOM 3042 C C . SER A 1 402 ? -136.945 4.647 295.862 1.00 29.59 ? 402 SER A C 1 ATOM 3043 O O . SER A 1 402 ? -138.169 4.768 295.738 1.00 31.16 ? 402 SER A O 1 ATOM 3044 C CB . SER A 1 402 ? -135.893 3.070 294.224 1.00 29.59 ? 402 SER A CB 1 ATOM 3045 O OG . SER A 1 402 ? -135.147 2.953 293.026 1.00 30.78 ? 402 SER A OG 1 ATOM 3046 N N . TRP A 1 403 ? -136.351 4.610 297.051 1.00 30.79 ? 403 TRP A N 1 ATOM 3047 C CA . TRP A 1 403 ? -137.084 4.727 298.303 1.00 28.49 ? 403 TRP A CA 1 ATOM 3048 C C . TRP A 1 403 ? -137.275 6.171 298.750 1.00 30.10 ? 403 TRP A C 1 ATOM 3049 O O . TRP A 1 403 ? -137.821 6.402 299.833 1.00 29.63 ? 403 TRP A O 1 ATOM 3050 C CB . TRP A 1 403 ? -136.369 3.929 299.399 1.00 31.38 ? 403 TRP A CB 1 ATOM 3051 C CG . TRP A 1 403 ? -134.875 4.024 299.322 1.00 32.42 ? 403 TRP A CG 1 ATOM 3052 C CD1 . TRP A 1 403 ? -134.035 3.179 298.656 1.00 33.30 ? 403 TRP A CD1 1 ATOM 3053 C CD2 . TRP A 1 403 ? -134.045 5.021 299.927 1.00 31.84 ? 403 TRP A CD2 1 ATOM 3054 N NE1 . TRP A 1 403 ? -132.733 3.588 298.810 1.00 34.10 ? 403 TRP A NE1 1 ATOM 3055 C CE2 . TRP A 1 403 ? -132.712 4.716 299.587 1.00 32.20 ? 403 TRP A CE2 1 ATOM 3056 C CE3 . TRP A 1 403 ? -134.298 6.141 300.724 1.00 32.67 ? 403 TRP A CE3 1 ATOM 3057 C CZ2 . TRP A 1 403 ? -131.637 5.490 300.015 1.00 33.84 ? 403 TRP A CZ2 1 ATOM 3058 C CZ3 . TRP A 1 403 ? -133.229 6.907 301.149 1.00 31.99 ? 403 TRP A CZ3 1 ATOM 3059 C CH2 . TRP A 1 403 ? -131.916 6.579 300.794 1.00 35.36 ? 403 TRP A CH2 1 ATOM 3060 N N . ASN A 1 404 ? -136.840 7.143 297.943 1.00 28.43 ? 404 ASN A N 1 ATOM 3061 C CA . ASN A 1 404 ? -137.048 8.558 298.253 1.00 28.57 ? 404 ASN A CA 1 ATOM 3062 C C . ASN A 1 404 ? -136.850 9.320 296.942 1.00 30.78 ? 404 ASN A C 1 ATOM 3063 O O . ASN A 1 404 ? -135.712 9.596 296.554 1.00 32.97 ? 404 ASN A O 1 ATOM 3064 C CB . ASN A 1 404 ? -136.093 9.037 299.334 1.00 29.40 ? 404 ASN A CB 1 ATOM 3065 C CG . ASN A 1 404 ? -136.306 10.493 299.698 1.00 39.36 ? 404 ASN A CG 1 ATOM 3066 O OD1 . ASN A 1 404 ? -135.902 11.395 298.964 1.00 36.47 ? 404 ASN A OD1 1 ATOM 3067 N ND2 . ASN A 1 404 ? -136.946 10.729 300.837 1.00 58.29 ? 404 ASN A ND2 1 ATOM 3068 N N . SER A 1 405 ? -137.956 9.654 296.281 1.00 32.29 ? 405 SER A N 1 ATOM 3069 C CA . SER A 1 405 ? -137.928 10.104 294.895 1.00 38.58 ? 405 SER A CA 1 ATOM 3070 C C . SER A 1 405 ? -137.675 11.600 294.739 1.00 36.28 ? 405 SER A C 1 ATOM 3071 O O . SER A 1 405 ? -137.812 12.120 293.626 1.00 37.85 ? 405 SER A O 1 ATOM 3072 C CB . SER A 1 405 ? -139.235 9.727 294.194 1.00 73.99 ? 405 SER A CB 1 ATOM 3073 O OG . SER A 1 405 ? -139.424 10.505 293.025 1.00 62.34 ? 405 SER A OG 1 ATOM 3074 N N . GLU A 1 406 ? -137.314 12.305 295.805 1.00 35.08 ? 406 GLU A N 1 ATOM 3075 C CA . GLU A 1 406 ? -136.828 13.673 295.653 1.00 37.47 ? 406 GLU A CA 1 ATOM 3076 C C . GLU A 1 406 ? -135.840 14.007 296.769 1.00 33.80 ? 406 GLU A C 1 ATOM 3077 O O . GLU A 1 406 ? -136.045 14.905 297.584 1.00 44.74 ? 406 GLU A O 1 ATOM 3078 C CB . GLU A 1 406 ? -137.973 14.683 295.605 1.00 43.68 ? 406 GLU A CB 1 ATOM 3079 C CG . GLU A 1 406 ? -137.563 15.972 294.892 1.00 51.71 ? 406 GLU A CG 1 ATOM 3080 C CD . GLU A 1 406 ? -138.607 17.067 294.968 1.00 76.05 ? 406 GLU A CD 1 ATOM 3081 O OE1 . GLU A 1 406 ? -139.639 16.866 295.640 1.00 92.07 ? 406 GLU A OE1 1 ATOM 3082 O OE2 . GLU A 1 406 ? -138.386 18.137 294.359 1.00 57.10 ? 406 GLU A OE2 1 ATOM 3083 N N . GLU A 1 407 ? -134.738 13.267 296.817 1.00 30.29 ? 407 GLU A N 1 ATOM 3084 C CA . GLU A 1 407 ? -133.552 13.749 297.509 1.00 26.11 ? 407 GLU A CA 1 ATOM 3085 C C . GLU A 1 407 ? -132.906 14.827 296.651 1.00 24.93 ? 407 GLU A C 1 ATOM 3086 O O . GLU A 1 407 ? -132.583 14.587 295.483 1.00 24.69 ? 407 GLU A O 1 ATOM 3087 C CB . GLU A 1 407 ? -132.579 12.603 297.769 1.00 25.71 ? 407 GLU A CB 1 ATOM 3088 C CG . GLU A 1 407 ? -131.321 13.011 298.521 1.00 23.27 ? 407 GLU A CG 1 ATOM 3089 C CD . GLU A 1 407 ? -131.611 13.525 299.918 1.00 23.57 ? 407 GLU A CD 1 ATOM 3090 O OE1 . GLU A 1 407 ? -132.315 12.826 300.675 1.00 27.38 ? 407 GLU A OE1 1 ATOM 3091 O OE2 . GLU A 1 407 ? -131.129 14.626 300.258 1.00 21.05 ? 407 GLU A OE2 1 ATOM 3092 N N . LEU A 1 408 ? -132.745 16.023 297.209 1.00 24.39 ? 408 LEU A N 1 ATOM 3093 C CA . LEU A 1 408 ? -132.178 17.116 296.433 1.00 24.04 ? 408 LEU A CA 1 ATOM 3094 C C . LEU A 1 408 ? -130.659 17.062 296.360 1.00 22.96 ? 408 LEU A C 1 ATOM 3095 O O . LEU A 1 408 ? -130.063 17.846 295.614 1.00 22.04 ? 408 LEU A O 1 ATOM 3096 C CB . LEU A 1 408 ? -132.635 18.457 297.009 1.00 26.78 ? 408 LEU A CB 1 ATOM 3097 C CG . LEU A 1 408 ? -134.155 18.634 297.012 1.00 26.83 ? 408 LEU A CG 1 ATOM 3098 C CD1 . LEU A 1 408 ? -134.599 19.558 298.135 1.00 43.63 ? 408 LEU A CD1 1 ATOM 3099 C CD2 . LEU A 1 408 ? -134.643 19.140 295.663 1.00 27.78 ? 408 LEU A CD2 1 ATOM 3100 N N . TYR A 1 409 ? -130.025 16.156 297.104 1.00 21.59 ? 409 TYR A N 1 ATOM 3101 C CA . TYR A 1 409 ? -128.580 15.943 297.014 1.00 22.66 ? 409 TYR A CA 1 ATOM 3102 C C . TYR A 1 409 ? -128.293 14.847 295.987 1.00 26.56 ? 409 TYR A C 1 ATOM 3103 O O . TYR A 1 409 ? -127.919 13.718 296.309 1.00 28.43 ? 409 TYR A O 1 ATOM 3104 C CB . TYR A 1 409 ? -128.005 15.593 298.380 1.00 23.75 ? 409 TYR A CB 1 ATOM 3105 C CG . TYR A 1 409 ? -127.464 16.775 299.151 1.00 27.66 ? 409 TYR A CG 1 ATOM 3106 C CD1 . TYR A 1 409 ? -127.778 18.076 298.780 1.00 30.66 ? 409 TYR A CD1 1 ATOM 3107 C CD2 . TYR A 1 409 ? -126.629 16.589 300.244 1.00 27.42 ? 409 TYR A CD2 1 ATOM 3108 C CE1 . TYR A 1 409 ? -127.281 19.157 299.484 1.00 36.10 ? 409 TYR A CE1 1 ATOM 3109 C CE2 . TYR A 1 409 ? -126.127 17.663 300.952 1.00 33.84 ? 409 TYR A CE2 1 ATOM 3110 C CZ . TYR A 1 409 ? -126.455 18.945 300.568 1.00 34.73 ? 409 TYR A CZ 1 ATOM 3111 O OH . TYR A 1 409 ? -125.957 20.018 301.271 1.00 37.18 ? 409 TYR A OH 1 ATOM 3112 N N . THR A 1 410 ? -128.494 15.203 294.721 1.00 25.72 ? 410 THR A N 1 ATOM 3113 C CA . THR A 1 410 ? -128.206 14.317 293.603 1.00 26.06 ? 410 THR A CA 1 ATOM 3114 C C . THR A 1 410 ? -127.423 15.070 292.539 1.00 31.22 ? 410 THR A C 1 ATOM 3115 O O . THR A 1 410 ? -127.392 16.303 292.512 1.00 46.04 ? 410 THR A O 1 ATOM 3116 C CB . THR A 1 410 ? -129.482 13.735 292.975 1.00 28.44 ? 410 THR A CB 1 ATOM 3117 O OG1 . THR A 1 410 ? -130.234 14.784 292.349 1.00 28.13 ? 410 THR A OG1 1 ATOM 3118 C CG2 . THR A 1 410 ? -130.334 13.028 294.019 1.00 39.68 ? 410 THR A CG2 1 ATOM 3119 N N . THR A 1 411 ? -126.786 14.300 291.654 1.00 32.56 ? 411 THR A N 1 ATOM 3120 C CA . THR A 1 411 ? -126.052 14.902 290.546 1.00 29.81 ? 411 THR A CA 1 ATOM 3121 C C . THR A 1 411 ? -126.992 15.642 289.605 1.00 31.92 ? 411 THR A C 1 ATOM 3122 O O . THR A 1 411 ? -126.641 16.700 289.070 1.00 35.51 ? 411 THR A O 1 ATOM 3123 C CB . THR A 1 411 ? -125.272 13.826 289.789 1.00 29.85 ? 411 THR A CB 1 ATOM 3124 O OG1 . THR A 1 411 ? -124.427 13.117 290.703 1.00 28.94 ? 411 THR A OG1 1 ATOM 3125 C CG2 . THR A 1 411 ? -124.417 14.451 288.698 1.00 28.05 ? 411 THR A CG2 1 ATOM 3126 N N . HIS A 1 412 ? -128.199 15.109 289.403 1.00 38.54 ? 412 HIS A N 1 ATOM 3127 C CA . HIS A 1 412 ? -129.143 15.733 288.481 1.00 32.58 ? 412 HIS A CA 1 ATOM 3128 C C . HIS A 1 412 ? -129.572 17.109 288.973 1.00 28.55 ? 412 HIS A C 1 ATOM 3129 O O . HIS A 1 412 ? -129.544 18.088 288.218 1.00 33.15 ? 412 HIS A O 1 ATOM 3130 C CB . HIS A 1 412 ? -130.361 14.832 288.283 1.00 43.97 ? 412 HIS A CB 1 ATOM 3131 C CG . HIS A 1 412 ? -131.395 15.413 287.371 1.00 33.42 ? 412 HIS A CG 1 ATOM 3132 N ND1 . HIS A 1 412 ? -131.236 15.465 286.003 1.00 34.70 ? 412 HIS A ND1 1 ATOM 3133 C CD2 . HIS A 1 412 ? -132.600 15.972 287.631 1.00 35.91 ? 412 HIS A CD2 1 ATOM 3134 C CE1 . HIS A 1 412 ? -132.300 16.029 285.459 1.00 44.05 ? 412 HIS A CE1 1 ATOM 3135 N NE2 . HIS A 1 412 ? -133.143 16.345 286.426 1.00 49.13 ? 412 HIS A NE2 1 ATOM 3136 N N . TYR A 1 413 ? -129.981 17.203 290.240 1.00 25.59 ? 413 TYR A N 1 ATOM 3137 C CA . TYR A 1 413 ? -130.460 18.478 290.761 1.00 27.11 ? 413 TYR A CA 1 ATOM 3138 C C . TYR A 1 413 ? -129.341 19.509 290.816 1.00 25.78 ? 413 TYR A C 1 ATOM 3139 O O . TYR A 1 413 ? -129.575 20.701 290.582 1.00 24.76 ? 413 TYR A O 1 ATOM 3140 C CB . TYR A 1 413 ? -131.079 18.280 292.144 1.00 26.93 ? 413 TYR A CB 1 ATOM 3141 C CG . TYR A 1 413 ? -131.845 19.483 292.641 1.00 22.72 ? 413 TYR A CG 1 ATOM 3142 C CD1 . TYR A 1 413 ? -133.124 19.755 292.173 1.00 22.26 ? 413 TYR A CD1 1 ATOM 3143 C CD2 . TYR A 1 413 ? -131.293 20.344 293.577 1.00 27.06 ? 413 TYR A CD2 1 ATOM 3144 C CE1 . TYR A 1 413 ? -133.831 20.853 292.623 1.00 23.37 ? 413 TYR A CE1 1 ATOM 3145 C CE2 . TYR A 1 413 ? -131.992 21.444 294.033 1.00 32.30 ? 413 TYR A CE2 1 ATOM 3146 C CZ . TYR A 1 413 ? -133.259 21.694 293.554 1.00 24.37 ? 413 TYR A CZ 1 ATOM 3147 O OH . TYR A 1 413 ? -133.956 22.790 294.009 1.00 23.49 ? 413 TYR A OH 1 ATOM 3148 N N . ALA A 1 414 ? -128.117 19.071 291.116 1.00 26.25 ? 414 ALA A N 1 ATOM 3149 C CA . ALA A 1 414 ? -126.992 19.998 291.161 1.00 22.61 ? 414 ALA A CA 1 ATOM 3150 C C . ALA A 1 414 ? -126.652 20.523 289.772 1.00 22.77 ? 414 ALA A C 1 ATOM 3151 O O . ALA A 1 414 ? -126.313 21.701 289.614 1.00 23.31 ? 414 ALA A O 1 ATOM 3152 C CB . ALA A 1 414 ? -125.777 19.321 291.791 1.00 24.27 ? 414 ALA A CB 1 ATOM 3153 N N . VAL A 1 415 ? -126.735 19.663 288.754 1.00 22.93 ? 415 VAL A N 1 ATOM 3154 C CA . VAL A 1 415 ? -126.455 20.099 287.387 1.00 24.54 ? 415 VAL A CA 1 ATOM 3155 C C . VAL A 1 415 ? -127.483 21.132 286.942 1.00 27.13 ? 415 VAL A C 1 ATOM 3156 O O . VAL A 1 415 ? -127.133 22.198 286.421 1.00 27.06 ? 415 VAL A O 1 ATOM 3157 C CB . VAL A 1 415 ? -126.416 18.892 286.433 1.00 24.40 ? 415 VAL A CB 1 ATOM 3158 C CG1 . VAL A 1 415 ? -126.496 19.355 284.988 1.00 27.38 ? 415 VAL A CG1 1 ATOM 3159 C CG2 . VAL A 1 415 ? -125.148 18.086 286.656 1.00 25.24 ? 415 VAL A CG2 1 ATOM 3160 N N . ASP A 1 416 ? -128.769 20.834 287.148 1.00 28.71 ? 416 ASP A N 1 ATOM 3161 C CA . ASP A 1 416 ? -129.814 21.777 286.765 1.00 44.43 ? 416 ASP A CA 1 ATOM 3162 C C . ASP A 1 416 ? -129.713 23.077 287.552 1.00 32.95 ? 416 ASP A C 1 ATOM 3163 O O . ASP A 1 416 ? -130.036 24.148 287.023 1.00 38.23 ? 416 ASP A O 1 ATOM 3164 C CB . ASP A 1 416 ? -131.193 21.145 286.960 1.00 29.96 ? 416 ASP A CB 1 ATOM 3165 C CG . ASP A 1 416 ? -131.598 20.261 285.798 1.00 35.50 ? 416 ASP A CG 1 ATOM 3166 O OD1 . ASP A 1 416 ? -132.454 20.690 284.995 1.00 28.91 ? 416 ASP A OD1 1 ATOM 3167 O OD2 . ASP A 1 416 ? -131.060 19.139 285.687 1.00 46.27 ? 416 ASP A OD2 1 ATOM 3168 N N . ALA A 1 417 ? -129.272 23.007 288.810 1.00 26.76 ? 417 ALA A N 1 ATOM 3169 C CA . ALA A 1 417 ? -129.101 24.223 289.600 1.00 30.60 ? 417 ALA A CA 1 ATOM 3170 C C . ALA A 1 417 ? -128.096 25.162 288.948 1.00 31.07 ? 417 ALA A C 1 ATOM 3171 O O . ALA A 1 417 ? -128.305 26.381 288.914 1.00 30.03 ? 417 ALA A O 1 ATOM 3172 C CB . ALA A 1 417 ? -128.667 23.870 291.022 1.00 28.68 ? 417 ALA A CB 1 ATOM 3173 N N . LEU A 1 418 ? -126.999 24.614 288.422 1.00 27.88 ? 418 LEU A N 1 ATOM 3174 C CA . LEU A 1 418 ? -126.060 25.430 287.662 1.00 25.88 ? 418 LEU A CA 1 ATOM 3175 C C . LEU A 1 418 ? -126.688 25.924 286.366 1.00 31.51 ? 418 LEU A C 1 ATOM 3176 O O . LEU A 1 418 ? -126.464 27.068 285.956 1.00 32.46 ? 418 LEU A O 1 ATOM 3177 C CB . LEU A 1 418 ? -124.789 24.632 287.367 1.00 27.62 ? 418 LEU A CB 1 ATOM 3178 C CG . LEU A 1 418 ? -123.903 24.252 288.552 1.00 27.73 ? 418 LEU A CG 1 ATOM 3179 C CD1 . LEU A 1 418 ? -122.773 23.347 288.094 1.00 23.92 ? 418 LEU A CD1 1 ATOM 3180 C CD2 . LEU A 1 418 ? -123.352 25.497 289.225 1.00 39.81 ? 418 LEU A CD2 1 ATOM 3181 N N . LEU A 1 419 ? -127.486 25.075 285.711 1.00 31.60 ? 419 LEU A N 1 ATOM 3182 C CA . LEU A 1 419 ? -128.081 25.448 284.432 1.00 33.67 ? 419 LEU A CA 1 ATOM 3183 C C . LEU A 1 419 ? -129.073 26.593 284.592 1.00 38.39 ? 419 LEU A C 1 ATOM 3184 O O . LEU A 1 419 ? -129.135 27.488 283.741 1.00 42.33 ? 419 LEU A O 1 ATOM 3185 C CB . LEU A 1 419 ? -128.761 24.234 283.800 1.00 32.91 ? 419 LEU A CB 1 ATOM 3186 C CG . LEU A 1 419 ? -127.846 23.068 283.423 1.00 30.14 ? 419 LEU A CG 1 ATOM 3187 C CD1 . LEU A 1 419 ? -128.653 21.913 282.854 1.00 30.60 ? 419 LEU A CD1 1 ATOM 3188 C CD2 . LEU A 1 419 ? -126.779 23.519 282.439 1.00 42.30 ? 419 LEU A CD2 1 ATOM 3189 N N . LYS A 1 420 ? -129.859 26.578 285.672 1.00 35.45 ? 420 LYS A N 1 ATOM 3190 C CA . LYS A 1 420 ? -130.813 27.657 285.909 1.00 41.16 ? 420 LYS A CA 1 ATOM 3191 C C . LYS A 1 420 ? -130.108 28.998 286.068 1.00 40.99 ? 420 LYS A C 1 ATOM 3192 O O . LYS A 1 420 ? -130.652 30.037 285.676 1.00 72.73 ? 420 LYS A O 1 ATOM 3193 C CB . LYS A 1 420 ? -131.660 27.337 287.144 1.00 46.65 ? 420 LYS A CB 1 ATOM 3194 C CG . LYS A 1 420 ? -132.407 28.523 287.742 1.00 72.46 ? 420 LYS A CG 1 ATOM 3195 C CD . LYS A 1 420 ? -133.840 28.591 287.239 1.00 81.33 ? 420 LYS A CD 1 ATOM 3196 C CE . LYS A 1 420 ? -134.667 29.586 288.041 1.00 59.05 ? 420 LYS A CE 1 ATOM 3197 N NZ . LYS A 1 420 ? -134.292 30.995 287.743 1.00 54.24 ? 420 LYS A NZ 1 ATOM 3198 N N . GLN A 1 421 ? -128.894 28.993 286.619 1.00 32.99 ? 421 GLN A N 1 ATOM 3199 C CA . GLN A 1 421 ? -128.119 30.216 286.773 1.00 33.08 ? 421 GLN A CA 1 ATOM 3200 C C . GLN A 1 421 ? -127.508 30.704 285.466 1.00 34.63 ? 421 GLN A C 1 ATOM 3201 O O . GLN A 1 421 ? -126.996 31.827 285.424 1.00 50.21 ? 421 GLN A O 1 ATOM 3202 C CB . GLN A 1 421 ? -127.010 30.006 287.806 1.00 27.88 ? 421 GLN A CB 1 ATOM 3203 C CG . GLN A 1 421 ? -127.515 29.624 289.185 1.00 26.20 ? 421 GLN A CG 1 ATOM 3204 C CD . GLN A 1 421 ? -126.435 29.705 290.243 1.00 22.54 ? 421 GLN A CD 1 ATOM 3205 O OE1 . GLN A 1 421 ? -125.374 30.286 290.019 1.00 20.12 ? 421 GLN A OE1 1 ATOM 3206 N NE2 . GLN A 1 421 ? -126.699 29.120 291.405 1.00 25.26 ? 421 GLN A NE2 1 ATOM 3207 N N . GLY A 1 422 ? -127.550 29.901 284.409 1.00 33.49 ? 422 GLY A N 1 ATOM 3208 C CA . GLY A 1 422 ? -126.952 30.265 283.144 1.00 35.22 ? 422 GLY A CA 1 ATOM 3209 C C . GLY A 1 422 ? -125.601 29.648 282.866 1.00 37.01 ? 422 GLY A C 1 ATOM 3210 O O . GLY A 1 422 ? -124.930 30.073 281.919 1.00 33.88 ? 422 GLY A O 1 ATOM 3211 N N . VAL A 1 423 ? -125.179 28.664 283.660 1.00 30.25 ? 423 VAL A N 1 ATOM 3212 C CA . VAL A 1 423 ? -123.890 28.021 283.444 1.00 29.14 ? 423 VAL A CA 1 ATOM 3213 C C . VAL A 1 423 ? -123.958 27.169 282.186 1.00 27.23 ? 423 VAL A C 1 ATOM 3214 O O . VAL A 1 423 ? -124.899 26.387 281.996 1.00 27.19 ? 423 VAL A O 1 ATOM 3215 C CB . VAL A 1 423 ? -123.499 27.178 284.667 1.00 27.90 ? 423 VAL A CB 1 ATOM 3216 C CG1 . VAL A 1 423 ? -122.236 26.379 284.386 1.00 26.38 ? 423 VAL A CG1 1 ATOM 3217 C CG2 . VAL A 1 423 ? -123.319 28.066 285.884 1.00 27.50 ? 423 VAL A CG2 1 ATOM 3218 N N . ASP A 1 424 ? -122.966 27.324 281.315 1.00 25.68 ? 424 ASP A N 1 ATOM 3219 C CA . ASP A 1 424 ? -122.893 26.490 280.127 1.00 25.25 ? 424 ASP A CA 1 ATOM 3220 C C . ASP A 1 424 ? -122.753 25.026 280.536 1.00 27.73 ? 424 ASP A C 1 ATOM 3221 O O . ASP A 1 424 ? -122.061 24.718 281.514 1.00 26.53 ? 424 ASP A O 1 ATOM 3222 C CB . ASP A 1 424 ? -121.709 26.899 279.249 1.00 28.15 ? 424 ASP A CB 1 ATOM 3223 C CG . ASP A 1 424 ? -121.811 28.328 278.760 1.00 47.35 ? 424 ASP A CG 1 ATOM 3224 O OD1 . ASP A 1 424 ? -122.897 28.929 278.897 1.00 37.24 ? 424 ASP A OD1 1 ATOM 3225 O OD2 . ASP A 1 424 ? -120.804 28.850 278.237 1.00 48.53 ? 424 ASP A OD2 1 ATOM 3226 N N . PRO A 1 425 ? -123.397 24.100 279.823 1.00 32.75 ? 425 PRO A N 1 ATOM 3227 C CA . PRO A 1 425 ? -123.214 22.684 280.165 1.00 28.97 ? 425 PRO A CA 1 ATOM 3228 C C . PRO A 1 425 ? -121.849 22.158 279.763 1.00 28.73 ? 425 PRO A C 1 ATOM 3229 O O . PRO A 1 425 ? -121.345 21.228 280.404 1.00 30.91 ? 425 PRO A O 1 ATOM 3230 C CB . PRO A 1 425 ? -124.351 21.981 279.408 1.00 29.84 ? 425 PRO A CB 1 ATOM 3231 C CG . PRO A 1 425 ? -124.830 22.960 278.370 1.00 30.34 ? 425 PRO A CG 1 ATOM 3232 C CD . PRO A 1 425 ? -124.146 24.283 278.569 1.00 29.55 ? 425 PRO A CD 1 ATOM 3233 N N . ASN A 1 426 ? -121.227 22.740 278.735 1.00 31.22 ? 426 ASN A N 1 ATOM 3234 C CA . ASN A 1 426 ? -119.884 22.333 278.339 1.00 32.42 ? 426 ASN A CA 1 ATOM 3235 C C . ASN A 1 426 ? -118.856 22.579 279.434 1.00 28.93 ? 426 ASN A C 1 ATOM 3236 O O . ASN A 1 426 ? -117.806 21.928 279.442 1.00 40.93 ? 426 ASN A O 1 ATOM 3237 C CB . ASN A 1 426 ? -119.466 23.072 277.067 1.00 34.64 ? 426 ASN A CB 1 ATOM 3238 C CG . ASN A 1 426 ? -119.921 22.365 275.806 1.00 52.79 ? 426 ASN A CG 1 ATOM 3239 O OD1 . ASN A 1 426 ? -120.758 21.463 275.852 1.00 55.35 ? 426 ASN A OD1 1 ATOM 3240 N ND2 . ASN A 1 426 ? -119.370 22.773 274.668 1.00 41.99 ? 426 ASN A ND2 1 ATOM 3241 N N . LYS A 1 427 ? -119.131 23.499 280.353 1.00 26.72 ? 427 LYS A N 1 ATOM 3242 C CA . LYS A 1 427 ? -118.202 23.844 281.418 1.00 27.09 ? 427 LYS A CA 1 ATOM 3243 C C . LYS A 1 427 ? -118.455 23.064 282.701 1.00 26.62 ? 427 LYS A C 1 ATOM 3244 O O . LYS A 1 427 ? -117.759 23.294 283.696 1.00 25.75 ? 427 LYS A O 1 ATOM 3245 C CB . LYS A 1 427 ? -118.277 25.347 281.706 1.00 25.67 ? 427 LYS A CB 1 ATOM 3246 C CG . LYS A 1 427 ? -118.123 26.210 280.463 1.00 30.41 ? 427 LYS A CG 1 ATOM 3247 C CD . LYS A 1 427 ? -118.314 27.687 280.767 1.00 33.39 ? 427 LYS A CD 1 ATOM 3248 C CE . LYS A 1 427 ? -116.989 28.383 281.028 1.00 35.39 ? 427 LYS A CE 1 ATOM 3249 N NZ . LYS A 1 427 ? -116.294 27.866 282.237 1.00 72.49 ? 427 LYS A NZ 1 ATOM 3250 N N . ILE A 1 428 ? -119.425 22.153 282.704 1.00 27.49 ? 428 ILE A N 1 ATOM 3251 C CA . ILE A 1 428 ? -119.786 21.380 283.887 1.00 25.77 ? 428 ILE A CA 1 ATOM 3252 C C . ILE A 1 428 ? -119.113 20.019 283.805 1.00 26.46 ? 428 ILE A C 1 ATOM 3253 O O . ILE A 1 428 ? -119.237 19.316 282.794 1.00 30.62 ? 428 ILE A O 1 ATOM 3254 C CB . ILE A 1 428 ? -121.311 21.232 284.012 1.00 23.26 ? 428 ILE A CB 1 ATOM 3255 C CG1 . ILE A 1 428 ? -121.977 22.607 284.090 1.00 24.67 ? 428 ILE A CG1 1 ATOM 3256 C CG2 . ILE A 1 428 ? -121.668 20.396 285.231 1.00 23.04 ? 428 ILE A CG2 1 ATOM 3257 C CD1 . ILE A 1 428 ? -123.486 22.551 284.138 1.00 27.80 ? 428 ILE A CD1 1 ATOM 3258 N N . ILE A 1 429 ? -118.404 19.644 284.866 1.00 25.76 ? 429 ILE A N 1 ATOM 3259 C CA . ILE A 1 429 ? -117.714 18.362 284.951 1.00 22.51 ? 429 ILE A CA 1 ATOM 3260 C C . ILE A 1 429 ? -118.319 17.583 286.109 1.00 24.42 ? 429 ILE A C 1 ATOM 3261 O O . ILE A 1 429 ? -118.315 18.056 287.252 1.00 25.30 ? 429 ILE A O 1 ATOM 3262 C CB . ILE A 1 429 ? -116.199 18.539 285.138 1.00 21.11 ? 429 ILE A CB 1 ATOM 3263 C CG1 . ILE A 1 429 ? -115.635 19.473 284.066 1.00 23.05 ? 429 ILE A CG1 1 ATOM 3264 C CG2 . ILE A 1 429 ? -115.498 17.193 285.083 1.00 43.66 ? 429 ILE A CG2 1 ATOM 3265 C CD1 . ILE A 1 429 ? -115.843 18.980 282.654 1.00 23.59 ? 429 ILE A CD1 1 ATOM 3266 N N . VAL A 1 430 ? -118.834 16.392 285.815 1.00 25.35 ? 430 VAL A N 1 ATOM 3267 C CA . VAL A 1 430 ? -119.521 15.580 286.813 1.00 21.87 ? 430 VAL A CA 1 ATOM 3268 C C . VAL A 1 430 ? -118.500 14.794 287.623 1.00 20.65 ? 430 VAL A C 1 ATOM 3269 O O . VAL A 1 430 ? -117.532 14.251 287.078 1.00 20.06 ? 430 VAL A O 1 ATOM 3270 C CB . VAL A 1 430 ? -120.543 14.651 286.134 1.00 21.37 ? 430 VAL A CB 1 ATOM 3271 C CG1 . VAL A 1 430 ? -121.088 13.631 287.120 1.00 29.14 ? 430 VAL A CG1 1 ATOM 3272 C CG2 . VAL A 1 430 ? -121.673 15.472 285.546 1.00 21.93 ? 430 VAL A CG2 1 ATOM 3273 N N . GLY A 1 431 ? -118.717 14.732 288.936 1.00 25.42 ? 431 GLY A N 1 ATOM 3274 C CA . GLY A 1 431 ? -117.781 14.082 289.833 1.00 24.71 ? 431 GLY A CA 1 ATOM 3275 C C . GLY A 1 431 ? -118.067 12.604 289.999 1.00 21.50 ? 431 GLY A C 1 ATOM 3276 O O . GLY A 1 431 ? -119.212 12.203 290.224 1.00 19.11 ? 431 GLY A O 1 ATOM 3277 N N . VAL A 1 432 ? -117.016 11.797 289.890 1.00 24.32 ? 432 VAL A N 1 ATOM 3278 C CA . VAL A 1 432 ? -117.081 10.359 290.116 1.00 27.12 ? 432 VAL A CA 1 ATOM 3279 C C . VAL A 1 432 ? -116.342 10.056 291.409 1.00 26.37 ? 432 VAL A C 1 ATOM 3280 O O . VAL A 1 432 ? -115.243 10.574 291.639 1.00 25.58 ? 432 VAL A O 1 ATOM 3281 C CB . VAL A 1 432 ? -116.480 9.575 288.937 1.00 24.09 ? 432 VAL A CB 1 ATOM 3282 C CG1 . VAL A 1 432 ? -116.523 8.081 289.213 1.00 22.75 ? 432 VAL A CG1 1 ATOM 3283 C CG2 . VAL A 1 432 ? -117.219 9.905 287.655 1.00 23.24 ? 432 VAL A CG2 1 ATOM 3284 N N . ALA A 1 433 ? -116.945 9.227 292.256 1.00 23.18 ? 433 ALA A N 1 ATOM 3285 C CA . ALA A 1 433 ? -116.352 8.841 293.530 1.00 21.46 ? 433 ALA A CA 1 ATOM 3286 C C . ALA A 1 433 ? -115.687 7.478 293.375 1.00 23.18 ? 433 ALA A C 1 ATOM 3287 O O . ALA A 1 433 ? -116.369 6.451 293.288 1.00 30.02 ? 433 ALA A O 1 ATOM 3288 C CB . ALA A 1 433 ? -117.404 8.812 294.634 1.00 24.38 ? 433 ALA A CB 1 ATOM 3289 N N . MET A 1 434 ? -114.357 7.473 293.346 1.00 22.82 ? 434 MET A N 1 ATOM 3290 C CA . MET A 1 434 ? -113.571 6.240 293.311 1.00 24.87 ? 434 MET A CA 1 ATOM 3291 C C . MET A 1 434 ? -113.423 5.604 294.684 1.00 25.56 ? 434 MET A C 1 ATOM 3292 O O . MET A 1 434 ? -112.398 4.986 294.984 1.00 26.27 ? 434 MET A O 1 ATOM 3293 C CB . MET A 1 434 ? -112.207 6.516 292.690 1.00 23.52 ? 434 MET A CB 1 ATOM 3294 C CG . MET A 1 434 ? -112.266 6.777 291.191 1.00 20.65 ? 434 MET A CG 1 ATOM 3295 S SD . MET A 1 434 ? -110.637 7.075 290.483 1.00 8.26 ? 434 MET A SD 1 ATOM 3296 C CE . MET A 1 434 ? -110.987 6.940 288.734 1.00 15.64 ? 434 MET A CE 1 ATOM 3297 N N . TYR A 1 435 ? -114.441 5.719 295.530 1.00 24.80 ? 435 TYR A N 1 ATOM 3298 C CA . TYR A 1 435 ? -114.405 5.188 296.887 1.00 25.52 ? 435 TYR A CA 1 ATOM 3299 C C . TYR A 1 435 ? -115.842 4.982 297.354 1.00 29.04 ? 435 TYR A C 1 ATOM 3300 O O . TYR A 1 435 ? -116.793 5.157 296.586 1.00 26.27 ? 435 TYR A O 1 ATOM 3301 C CB . TYR A 1 435 ? -113.629 6.126 297.818 1.00 29.49 ? 435 TYR A CB 1 ATOM 3302 C CG . TYR A 1 435 ? -114.231 7.511 297.916 1.00 27.41 ? 435 TYR A CG 1 ATOM 3303 C CD1 . TYR A 1 435 ? -113.966 8.476 296.954 1.00 25.42 ? 435 TYR A CD1 1 ATOM 3304 C CD2 . TYR A 1 435 ? -115.073 7.849 298.966 1.00 29.57 ? 435 TYR A CD2 1 ATOM 3305 C CE1 . TYR A 1 435 ? -114.519 9.741 297.035 1.00 26.10 ? 435 TYR A CE1 1 ATOM 3306 C CE2 . TYR A 1 435 ? -115.630 9.111 299.057 1.00 36.37 ? 435 TYR A CE2 1 ATOM 3307 C CZ . TYR A 1 435 ? -115.350 10.053 298.090 1.00 33.03 ? 435 TYR A CZ 1 ATOM 3308 O OH . TYR A 1 435 ? -115.906 11.310 298.181 1.00 51.64 ? 435 TYR A OH 1 ATOM 3309 N N . GLY A 1 436 ? -116.002 4.613 298.620 1.00 38.33 ? 436 GLY A N 1 ATOM 3310 C CA . GLY A 1 436 ? -117.327 4.433 299.173 1.00 30.88 ? 436 GLY A CA 1 ATOM 3311 C C . GLY A 1 436 ? -117.399 4.690 300.662 1.00 29.24 ? 436 GLY A C 1 ATOM 3312 O O . GLY A 1 436 ? -116.524 4.254 301.415 1.00 45.68 ? 436 GLY A O 1 ATOM 3313 N N . ARG A 1 437 ? -118.431 5.403 301.098 1.00 26.72 ? 437 ARG A N 1 ATOM 3314 C CA . ARG A 1 437 ? -118.688 5.623 302.513 1.00 30.65 ? 437 ARG A CA 1 ATOM 3315 C C . ARG A 1 437 ? -119.757 4.652 302.992 1.00 35.69 ? 437 ARG A C 1 ATOM 3316 O O . ARG A 1 437 ? -120.697 4.337 302.257 1.00 39.23 ? 437 ARG A O 1 ATOM 3317 C CB . ARG A 1 437 ? -119.121 7.065 302.779 1.00 34.68 ? 437 ARG A CB 1 ATOM 3318 C CG . ARG A 1 437 ? -117.963 8.041 302.844 1.00 43.73 ? 437 ARG A CG 1 ATOM 3319 C CD . ARG A 1 437 ? -118.417 9.420 303.279 1.00 32.39 ? 437 ARG A CD 1 ATOM 3320 N NE . ARG A 1 437 ? -117.293 10.238 303.723 1.00 29.52 ? 437 ARG A NE 1 ATOM 3321 C CZ . ARG A 1 437 ? -116.468 10.885 302.908 1.00 33.64 ? 437 ARG A CZ 1 ATOM 3322 N NH1 . ARG A 1 437 ? -116.632 10.812 301.595 1.00 36.99 ? 437 ARG A NH1 1 ATOM 3323 N NH2 . ARG A 1 437 ? -115.472 11.603 303.407 1.00 37.03 ? 437 ARG A NH2 1 ATOM 3324 N N . GLY A 1 438 ? -119.605 4.175 304.226 1.00 36.83 ? 438 GLY A N 1 ATOM 3325 C CA . GLY A 1 438 ? -120.503 3.158 304.730 1.00 34.34 ? 438 GLY A CA 1 ATOM 3326 C C . GLY A 1 438 ? -120.717 3.256 306.224 1.00 39.81 ? 438 GLY A C 1 ATOM 3327 O O . GLY A 1 438 ? -120.031 3.995 306.934 1.00 52.65 ? 438 GLY A O 1 ATOM 3328 N N . TRP A 1 439 ? -121.693 2.483 306.691 1.00 37.91 ? 439 TRP A N 1 ATOM 3329 C CA . TRP A 1 439 ? -122.043 2.398 308.099 1.00 36.51 ? 439 TRP A CA 1 ATOM 3330 C C . TRP A 1 439 ? -121.996 0.940 308.531 1.00 38.68 ? 439 TRP A C 1 ATOM 3331 O O . TRP A 1 439 ? -122.178 0.031 307.716 1.00 45.35 ? 439 TRP A O 1 ATOM 3332 C CB . TRP A 1 439 ? -123.440 2.977 308.370 1.00 36.93 ? 439 TRP A CB 1 ATOM 3333 C CG . TRP A 1 439 ? -123.649 4.365 307.835 1.00 35.19 ? 439 TRP A CG 1 ATOM 3334 C CD1 . TRP A 1 439 ? -123.637 5.527 308.548 1.00 37.47 ? 439 TRP A CD1 1 ATOM 3335 C CD2 . TRP A 1 439 ? -123.914 4.733 306.474 1.00 33.73 ? 439 TRP A CD2 1 ATOM 3336 N NE1 . TRP A 1 439 ? -123.872 6.596 307.718 1.00 35.71 ? 439 TRP A NE1 1 ATOM 3337 C CE2 . TRP A 1 439 ? -124.045 6.135 306.439 1.00 34.00 ? 439 TRP A CE2 1 ATOM 3338 C CE3 . TRP A 1 439 ? -124.050 4.014 305.283 1.00 33.62 ? 439 TRP A CE3 1 ATOM 3339 C CZ2 . TRP A 1 439 ? -124.305 6.832 305.261 1.00 28.61 ? 439 TRP A CZ2 1 ATOM 3340 C CZ3 . TRP A 1 439 ? -124.307 4.708 304.114 1.00 33.36 ? 439 TRP A CZ3 1 ATOM 3341 C CH2 . TRP A 1 439 ? -124.432 6.102 304.112 1.00 25.97 ? 439 TRP A CH2 1 ATOM 3342 N N . THR A 1 440 ? -121.752 0.721 309.820 1.00 38.81 ? 440 THR A N 1 ATOM 3343 C CA . THR A 1 440 ? -121.691 -0.619 310.381 1.00 39.89 ? 440 THR A CA 1 ATOM 3344 C C . THR A 1 440 ? -122.804 -0.809 311.402 1.00 51.28 ? 440 THR A C 1 ATOM 3345 O O . THR A 1 440 ? -123.264 0.149 312.031 1.00 60.63 ? 440 THR A O 1 ATOM 3346 C CB . THR A 1 440 ? -120.332 -0.898 311.039 1.00 42.87 ? 440 THR A CB 1 ATOM 3347 O OG1 . THR A 1 440 ? -120.296 -2.253 311.505 1.00 44.10 ? 440 THR A OG1 1 ATOM 3348 C CG2 . THR A 1 440 ? -120.105 0.036 312.216 1.00 43.20 ? 440 THR A CG2 1 ATOM 3349 N N . GLY A 1 441 ? -123.234 -2.059 311.556 1.00 47.21 ? 441 GLY A N 1 ATOM 3350 C CA . GLY A 1 441 ? -124.274 -2.398 312.507 1.00 45.44 ? 441 GLY A CA 1 ATOM 3351 C C . GLY A 1 441 ? -125.587 -1.688 312.255 1.00 43.25 ? 441 GLY A C 1 ATOM 3352 O O . GLY A 1 441 ? -126.194 -1.149 313.185 1.00 50.58 ? 441 GLY A O 1 ATOM 3353 N N . VAL A 1 442 ? -126.035 -1.676 311.000 1.00 40.52 ? 442 VAL A N 1 ATOM 3354 C CA . VAL A 1 442 ? -127.292 -1.023 310.652 1.00 43.87 ? 442 VAL A CA 1 ATOM 3355 C C . VAL A 1 442 ? -128.439 -1.789 311.300 1.00 47.26 ? 442 VAL A C 1 ATOM 3356 O O . VAL A 1 442 ? -128.654 -2.973 311.016 1.00 56.66 ? 442 VAL A O 1 ATOM 3357 C CB . VAL A 1 442 ? -127.465 -0.940 309.131 1.00 44.41 ? 442 VAL A CB 1 ATOM 3358 C CG1 . VAL A 1 442 ? -128.833 -0.374 308.783 1.00 58.44 ? 442 VAL A CG1 1 ATOM 3359 C CG2 . VAL A 1 442 ? -126.357 -0.096 308.517 1.00 44.77 ? 442 VAL A CG2 1 ATOM 3360 N N . THR A 1 443 ? -129.180 -1.115 312.173 1.00 45.65 ? 443 THR A N 1 ATOM 3361 C CA . THR A 1 443 ? -130.230 -1.737 312.965 1.00 46.15 ? 443 THR A CA 1 ATOM 3362 C C . THR A 1 443 ? -131.552 -1.011 312.756 1.00 49.82 ? 443 THR A C 1 ATOM 3363 O O . THR A 1 443 ? -131.612 0.067 312.157 1.00 84.36 ? 443 THR A O 1 ATOM 3364 C CB . THR A 1 443 ? -129.869 -1.732 314.457 1.00 61.11 ? 443 THR A CB 1 ATOM 3365 O OG1 . THR A 1 443 ? -129.334 -0.451 314.815 1.00 47.72 ? 443 THR A OG1 1 ATOM 3366 C CG2 . THR A 1 443 ? -128.837 -2.803 314.762 1.00 54.03 ? 443 THR A CG2 1 ATOM 3367 N N . ASN A 1 444 ? -132.618 -1.630 313.263 1.00 48.31 ? 444 ASN A N 1 ATOM 3368 C CA . ASN A 1 444 ? -133.949 -1.030 313.347 1.00 44.32 ? 444 ASN A CA 1 ATOM 3369 C C . ASN A 1 444 ? -134.428 -0.543 311.976 1.00 46.83 ? 444 ASN A C 1 ATOM 3370 O O . ASN A 1 444 ? -134.559 0.651 311.710 1.00 48.08 ? 444 ASN A O 1 ATOM 3371 C CB . ASN A 1 444 ? -133.956 0.109 314.371 1.00 44.82 ? 444 ASN A CB 1 ATOM 3372 C CG . ASN A 1 444 ? -133.520 -0.346 315.750 1.00 40.42 ? 444 ASN A CG 1 ATOM 3373 O OD1 . ASN A 1 444 ? -133.744 -1.493 316.137 1.00 39.81 ? 444 ASN A OD1 1 ATOM 3374 N ND2 . ASN A 1 444 ? -132.892 0.552 316.499 1.00 43.71 ? 444 ASN A ND2 1 ATOM 3375 N N . TYR A 1 445 ? -134.695 -1.516 311.108 1.00 47.14 ? 445 TYR A N 1 ATOM 3376 C CA . TYR A 1 445 ? -135.131 -1.232 309.750 1.00 48.91 ? 445 TYR A CA 1 ATOM 3377 C C . TYR A 1 445 ? -136.243 -2.192 309.358 1.00 52.55 ? 445 TYR A C 1 ATOM 3378 O O . TYR A 1 445 ? -136.337 -3.307 309.880 1.00 78.05 ? 445 TYR A O 1 ATOM 3379 C CB . TYR A 1 445 ? -133.969 -1.340 308.751 1.00 55.09 ? 445 TYR A CB 1 ATOM 3380 C CG . TYR A 1 445 ? -133.385 -2.730 308.638 1.00 61.61 ? 445 TYR A CG 1 ATOM 3381 C CD1 . TYR A 1 445 ? -133.860 -3.632 307.693 1.00 63.14 ? 445 TYR A CD1 1 ATOM 3382 C CD2 . TYR A 1 445 ? -132.364 -3.145 309.482 1.00 65.04 ? 445 TYR A CD2 1 ATOM 3383 C CE1 . TYR A 1 445 ? -133.332 -4.903 307.589 1.00 84.30 ? 445 TYR A CE1 1 ATOM 3384 C CE2 . TYR A 1 445 ? -131.829 -4.415 309.386 1.00 70.88 ? 445 TYR A CE2 1 ATOM 3385 C CZ . TYR A 1 445 ? -132.317 -5.289 308.438 1.00 82.48 ? 445 TYR A CZ 1 ATOM 3386 O OH . TYR A 1 445 ? -131.787 -6.555 308.339 1.00 99.83 ? 445 TYR A OH 1 ATOM 3387 N N . THR A 1 446 ? -137.080 -1.747 308.429 1.00 51.26 ? 446 THR A N 1 ATOM 3388 C CA . THR A 1 446 ? -138.143 -2.564 307.867 1.00 51.24 ? 446 THR A CA 1 ATOM 3389 C C . THR A 1 446 ? -137.747 -3.058 306.481 1.00 54.34 ? 446 THR A C 1 ATOM 3390 O O . THR A 1 446 ? -136.809 -2.551 305.861 1.00 52.03 ? 446 THR A O 1 ATOM 3391 C CB . THR A 1 446 ? -139.450 -1.774 307.776 1.00 46.29 ? 446 THR A CB 1 ATOM 3392 O OG1 . THR A 1 446 ? -139.281 -0.672 306.875 1.00 45.84 ? 446 THR A OG1 1 ATOM 3393 C CG2 . THR A 1 446 ? -139.850 -1.240 309.142 1.00 41.60 ? 446 THR A CG2 1 ATOM 3394 N N . ASN A 1 447 ? -138.477 -4.062 306.007 1.00 73.69 ? 447 ASN A N 1 ATOM 3395 C CA . ASN A 1 447 ? -138.334 -4.573 304.637 1.00 60.99 ? 447 ASN A CA 1 ATOM 3396 C C . ASN A 1 447 ? -136.889 -5.043 304.438 1.00 55.01 ? 447 ASN A C 1 ATOM 3397 O O . ASN A 1 447 ? -136.228 -5.483 305.388 1.00 57.29 ? 447 ASN A O 1 ATOM 3398 C CB . ASN A 1 447 ? -138.801 -3.506 303.658 1.00 60.55 ? 447 ASN A CB 1 ATOM 3399 C CG . ASN A 1 447 ? -139.055 -4.054 302.269 1.00 66.01 ? 447 ASN A CG 1 ATOM 3400 O OD1 . ASN A 1 447 ? -139.327 -5.240 302.100 1.00 54.73 ? 447 ASN A OD1 1 ATOM 3401 N ND2 . ASN A 1 447 ? -138.964 -3.188 301.265 1.00 54.04 ? 447 ASN A ND2 1 ATOM 3402 N N . ASP A 1 448 ? -136.390 -4.961 303.204 1.00 54.31 ? 448 ASP A N 1 ATOM 3403 C CA . ASP A 1 448 ? -134.985 -5.187 302.897 1.00 57.67 ? 448 ASP A CA 1 ATOM 3404 C C . ASP A 1 448 ? -134.280 -3.893 302.505 1.00 63.22 ? 448 ASP A C 1 ATOM 3405 O O . ASP A 1 448 ? -133.205 -3.931 301.898 1.00 79.73 ? 448 ASP A O 1 ATOM 3406 C CB . ASP A 1 448 ? -134.839 -6.239 301.795 1.00 61.46 ? 448 ASP A CB 1 ATOM 3407 C CG . ASP A 1 448 ? -135.423 -5.785 300.470 1.00 52.44 ? 448 ASP A CG 1 ATOM 3408 O OD1 . ASP A 1 448 ? -136.275 -4.872 300.472 1.00 58.76 ? 448 ASP A OD1 1 ATOM 3409 O OD2 . ASP A 1 448 ? -135.027 -6.344 299.426 1.00 41.56 ? 448 ASP A OD2 1 ATOM 3410 N N . ASN A 1 449 ? -134.875 -2.748 302.829 1.00 66.06 ? 449 ASN A N 1 ATOM 3411 C CA . ASN A 1 449 ? -134.253 -1.450 302.610 1.00 55.48 ? 449 ASN A CA 1 ATOM 3412 C C . ASN A 1 449 ? -133.507 -1.045 303.876 1.00 67.05 ? 449 ASN A C 1 ATOM 3413 O O . ASN A 1 449 ? -134.125 -0.825 304.923 1.00 65.53 ? 449 ASN A O 1 ATOM 3414 C CB . ASN A 1 449 ? -135.303 -0.404 302.239 1.00 47.18 ? 449 ASN A CB 1 ATOM 3415 C CG . ASN A 1 449 ? -134.723 0.991 302.133 1.00 44.51 ? 449 ASN A CG 1 ATOM 3416 O OD1 . ASN A 1 449 ? -133.549 1.164 301.804 1.00 52.72 ? 449 ASN A OD1 1 ATOM 3417 N ND2 . ASN A 1 449 ? -135.542 1.996 302.413 1.00 44.02 ? 449 ASN A ND2 1 ATOM 3418 N N . TYR A 1 450 ? -132.185 -0.956 303.780 1.00 51.54 ? 450 TYR A N 1 ATOM 3419 C CA . TYR A 1 450 ? -131.339 -0.699 304.937 1.00 49.43 ? 450 TYR A CA 1 ATOM 3420 C C . TYR A 1 450 ? -131.026 0.778 305.131 1.00 46.98 ? 450 TYR A C 1 ATOM 3421 O O . TYR A 1 450 ? -130.293 1.123 306.064 1.00 67.28 ? 450 TYR A O 1 ATOM 3422 C CB . TYR A 1 450 ? -130.040 -1.499 304.817 1.00 51.49 ? 450 TYR A CB 1 ATOM 3423 C CG . TYR A 1 450 ? -130.240 -2.862 304.194 1.00 54.95 ? 450 TYR A CG 1 ATOM 3424 C CD1 . TYR A 1 450 ? -130.694 -3.933 304.953 1.00 66.46 ? 450 TYR A CD1 1 ATOM 3425 C CD2 . TYR A 1 450 ? -129.978 -3.078 302.848 1.00 49.04 ? 450 TYR A CD2 1 ATOM 3426 C CE1 . TYR A 1 450 ? -130.883 -5.179 304.388 1.00 61.59 ? 450 TYR A CE1 1 ATOM 3427 C CE2 . TYR A 1 450 ? -130.161 -4.321 302.274 1.00 49.93 ? 450 TYR A CE2 1 ATOM 3428 C CZ . TYR A 1 450 ? -130.614 -5.368 303.049 1.00 54.47 ? 450 TYR A CZ 1 ATOM 3429 O OH . TYR A 1 450 ? -130.799 -6.608 302.483 1.00 59.51 ? 450 TYR A OH 1 ATOM 3430 N N . PHE A 1 451 ? -131.557 1.653 304.280 1.00 46.90 ? 451 PHE A N 1 ATOM 3431 C CA . PHE A 1 451 ? -131.389 3.090 304.444 1.00 54.27 ? 451 PHE A CA 1 ATOM 3432 C C . PHE A 1 451 ? -132.496 3.722 305.274 1.00 41.07 ? 451 PHE A C 1 ATOM 3433 O O . PHE A 1 451 ? -132.362 4.882 305.680 1.00 37.47 ? 451 PHE A O 1 ATOM 3434 C CB . PHE A 1 451 ? -131.316 3.769 303.073 1.00 41.65 ? 451 PHE A CB 1 ATOM 3435 C CG . PHE A 1 451 ? -130.254 3.202 302.176 1.00 54.72 ? 451 PHE A CG 1 ATOM 3436 C CD1 . PHE A 1 451 ? -128.941 3.627 302.283 1.00 62.83 ? 451 PHE A CD1 1 ATOM 3437 C CD2 . PHE A 1 451 ? -130.567 2.238 301.232 1.00 42.98 ? 451 PHE A CD2 1 ATOM 3438 C CE1 . PHE A 1 451 ? -127.959 3.107 301.461 1.00 56.44 ? 451 PHE A CE1 1 ATOM 3439 C CE2 . PHE A 1 451 ? -129.588 1.713 300.407 1.00 55.63 ? 451 PHE A CE2 1 ATOM 3440 C CZ . PHE A 1 451 ? -128.283 2.148 300.523 1.00 42.48 ? 451 PHE A CZ 1 ATOM 3441 N N . SER A 1 452 ? -133.583 2.994 305.531 1.00 41.87 ? 452 SER A N 1 ATOM 3442 C CA . SER A 1 452 ? -134.628 3.467 306.427 1.00 41.57 ? 452 SER A CA 1 ATOM 3443 C C . SER A 1 452 ? -134.284 3.252 307.893 1.00 42.34 ? 452 SER A C 1 ATOM 3444 O O . SER A 1 452 ? -134.990 3.775 308.762 1.00 64.20 ? 452 SER A O 1 ATOM 3445 C CB . SER A 1 452 ? -135.951 2.769 306.105 1.00 40.82 ? 452 SER A CB 1 ATOM 3446 O OG . SER A 1 452 ? -135.790 1.362 306.090 1.00 44.78 ? 452 SER A OG 1 ATOM 3447 N N . GLY A 1 453 ? -133.227 2.503 308.186 1.00 41.56 ? 453 GLY A N 1 ATOM 3448 C CA . GLY A 1 453 ? -132.830 2.211 309.546 1.00 42.13 ? 453 GLY A CA 1 ATOM 3449 C C . GLY A 1 453 ? -131.806 3.188 310.081 1.00 37.13 ? 453 GLY A C 1 ATOM 3450 O O . GLY A 1 453 ? -131.631 4.296 309.567 1.00 34.85 ? 453 GLY A O 1 ATOM 3451 N N . THR A 1 454 ? -131.123 2.764 311.142 1.00 33.32 ? 454 THR A N 1 ATOM 3452 C CA . THR A 1 454 ? -130.103 3.568 311.802 1.00 34.64 ? 454 THR A CA 1 ATOM 3453 C C . THR A 1 454 ? -128.865 2.716 312.033 1.00 40.21 ? 454 THR A C 1 ATOM 3454 O O . THR A 1 454 ? -128.960 1.621 312.596 1.00 44.10 ? 454 THR A O 1 ATOM 3455 C CB . THR A 1 454 ? -130.605 4.127 313.140 1.00 34.61 ? 454 THR A CB 1 ATOM 3456 O OG1 . THR A 1 454 ? -130.913 3.044 314.026 1.00 35.00 ? 454 THR A OG1 1 ATOM 3457 C CG2 . THR A 1 454 ? -131.846 4.985 312.939 1.00 38.13 ? 454 THR A CG2 1 ATOM 3458 N N . GLY A 1 455 ? -127.708 3.219 311.599 1.00 40.00 ? 455 GLY A N 1 ATOM 3459 C CA . GLY A 1 455 ? -126.459 2.534 311.847 1.00 39.87 ? 455 GLY A CA 1 ATOM 3460 C C . GLY A 1 455 ? -125.892 2.847 313.219 1.00 49.12 ? 455 GLY A C 1 ATOM 3461 O O . GLY A 1 455 ? -126.376 3.716 313.943 1.00 39.76 ? 455 GLY A O 1 ATOM 3462 N N . ASN A 1 456 ? -124.837 2.112 313.580 1.00 46.76 ? 456 ASN A N 1 ATOM 3463 C CA . ASN A 1 456 ? -124.162 2.277 314.867 1.00 45.62 ? 456 ASN A CA 1 ATOM 3464 C C . ASN A 1 456 ? -122.651 2.339 314.625 1.00 37.80 ? 456 ASN A C 1 ATOM 3465 O O . ASN A 1 456 ? -121.906 1.428 314.987 1.00 36.66 ? 456 ASN A O 1 ATOM 3466 C CB . ASN A 1 456 ? -124.532 1.151 315.835 1.00 38.41 ? 456 ASN A CB 1 ATOM 3467 C CG . ASN A 1 456 ? -123.996 1.386 317.235 1.00 38.41 ? 456 ASN A CG 1 ATOM 3468 O OD1 . ASN A 1 456 ? -123.240 0.574 317.768 1.00 37.73 ? 456 ASN A OD1 1 ATOM 3469 N ND2 . ASN A 1 456 ? -124.386 2.503 317.838 1.00 48.46 ? 456 ASN A ND2 1 ATOM 3470 N N . GLY A 1 457 ? -122.204 3.428 314.005 1.00 35.54 ? 457 GLY A N 1 ATOM 3471 C CA . GLY A 1 457 ? -120.794 3.655 313.798 1.00 38.71 ? 457 GLY A CA 1 ATOM 3472 C C . GLY A 1 457 ? -120.381 3.556 312.344 1.00 38.51 ? 457 GLY A C 1 ATOM 3473 O O . GLY A 1 457 ? -121.139 3.096 311.484 1.00 46.98 ? 457 GLY A O 1 ATOM 3474 N N . PRO A 1 458 ? -119.163 3.994 312.044 1.00 36.72 ? 458 PRO A N 1 ATOM 3475 C CA . PRO A 1 458 ? -118.668 3.928 310.668 1.00 37.55 ? 458 PRO A CA 1 ATOM 3476 C C . PRO A 1 458 ? -118.137 2.549 310.314 1.00 36.63 ? 458 PRO A C 1 ATOM 3477 O O . PRO A 1 458 ? -117.635 1.807 311.162 1.00 36.06 ? 458 PRO A O 1 ATOM 3478 C CB . PRO A 1 458 ? -117.542 4.968 310.653 1.00 47.74 ? 458 PRO A CB 1 ATOM 3479 C CG . PRO A 1 458 ? -117.037 4.969 312.056 1.00 41.81 ? 458 PRO A CG 1 ATOM 3480 C CD . PRO A 1 458 ? -118.227 4.698 312.939 1.00 37.27 ? 458 PRO A CD 1 ATOM 3481 N N . VAL A 1 459 ? -118.251 2.217 309.027 1.00 36.92 ? 459 VAL A N 1 ATOM 3482 C CA . VAL A 1 459 ? -117.760 0.933 308.542 1.00 36.99 ? 459 VAL A CA 1 ATOM 3483 C C . VAL A 1 459 ? -116.234 0.908 308.589 1.00 39.82 ? 459 VAL A C 1 ATOM 3484 O O . VAL A 1 459 ? -115.561 1.945 308.596 1.00 50.26 ? 459 VAL A O 1 ATOM 3485 C CB . VAL A 1 459 ? -118.282 0.664 307.119 1.00 37.43 ? 459 VAL A CB 1 ATOM 3486 C CG1 . VAL A 1 459 ? -117.570 1.554 306.110 1.00 46.02 ? 459 VAL A CG1 1 ATOM 3487 C CG2 . VAL A 1 459 ? -118.148 -0.810 306.749 1.00 43.20 ? 459 VAL A CG2 1 ATOM 3488 N N . SER A 1 460 ? -115.683 -0.303 308.641 1.00 42.79 ? 460 SER A N 1 ATOM 3489 C CA . SER A 1 460 ? -114.236 -0.476 308.599 1.00 49.13 ? 460 SER A CA 1 ATOM 3490 C C . SER A 1 460 ? -113.707 -0.033 307.241 1.00 56.21 ? 460 SER A C 1 ATOM 3491 O O . SER A 1 460 ? -114.147 -0.534 306.201 1.00 53.01 ? 460 SER A O 1 ATOM 3492 C CB . SER A 1 460 ? -113.870 -1.933 308.871 1.00 47.93 ? 460 SER A CB 1 ATOM 3493 O OG . SER A 1 460 ? -114.108 -2.740 307.731 1.00 55.95 ? 460 SER A OG 1 ATOM 3494 N N . GLY A 1 461 ? -112.760 0.907 307.248 1.00 47.71 ? 461 GLY A N 1 ATOM 3495 C CA . GLY A 1 461 ? -112.236 1.491 306.037 1.00 59.06 ? 461 GLY A CA 1 ATOM 3496 C C . GLY A 1 461 ? -110.826 1.018 305.715 1.00 42.50 ? 461 GLY A C 1 ATOM 3497 O O . GLY A 1 461 ? -110.138 0.400 306.526 1.00 38.49 ? 461 GLY A O 1 ATOM 3498 N N . THR A 1 462 ? -110.406 1.329 304.489 1.00 36.22 ? 462 THR A N 1 ATOM 3499 C CA . THR A 1 462 ? -109.074 0.973 304.016 1.00 33.29 ? 462 THR A CA 1 ATOM 3500 C C . THR A 1 462 ? -108.011 1.760 304.770 1.00 38.41 ? 462 THR A C 1 ATOM 3501 O O . THR A 1 462 ? -107.252 1.193 305.562 1.00 65.56 ? 462 THR A O 1 ATOM 3502 C CB . THR A 1 462 ? -108.949 1.229 302.513 1.00 31.04 ? 462 THR A CB 1 ATOM 3503 O OG1 . THR A 1 462 ? -110.097 0.699 301.838 1.00 30.27 ? 462 THR A OG1 1 ATOM 3504 C CG2 . THR A 1 462 ? -107.695 0.565 301.965 1.00 33.53 ? 462 THR A CG2 1 ATOM 3505 N N . TRP A 1 463 ? -107.949 3.067 304.525 1.00 35.35 ? 463 TRP A N 1 ATOM 3506 C CA . TRP A 1 463 ? -107.020 3.953 305.214 1.00 33.32 ? 463 TRP A CA 1 ATOM 3507 C C . TRP A 1 463 ? -107.683 4.728 306.342 1.00 38.80 ? 463 TRP A C 1 ATOM 3508 O O . TRP A 1 463 ? -107.073 4.925 307.397 1.00 54.67 ? 463 TRP A O 1 ATOM 3509 C CB . TRP A 1 463 ? -106.393 4.933 304.219 1.00 30.25 ? 463 TRP A CB 1 ATOM 3510 C CG . TRP A 1 463 ? -106.050 4.297 302.910 1.00 26.73 ? 463 TRP A CG 1 ATOM 3511 C CD1 . TRP A 1 463 ? -106.717 4.445 301.730 1.00 26.56 ? 463 TRP A CD1 1 ATOM 3512 C CD2 . TRP A 1 463 ? -104.970 3.393 302.650 1.00 24.83 ? 463 TRP A CD2 1 ATOM 3513 N NE1 . TRP A 1 463 ? -106.114 3.698 300.747 1.00 23.04 ? 463 TRP A NE1 1 ATOM 3514 C CE2 . TRP A 1 463 ? -105.039 3.042 301.287 1.00 24.87 ? 463 TRP A CE2 1 ATOM 3515 C CE3 . TRP A 1 463 ? -103.949 2.850 303.435 1.00 25.25 ? 463 TRP A CE3 1 ATOM 3516 C CZ2 . TRP A 1 463 ? -104.126 2.174 300.693 1.00 25.71 ? 463 TRP A CZ2 1 ATOM 3517 C CZ3 . TRP A 1 463 ? -103.044 1.988 302.843 1.00 23.95 ? 463 TRP A CZ3 1 ATOM 3518 C CH2 . TRP A 1 463 ? -103.139 1.658 301.486 1.00 22.38 ? 463 TRP A CH2 1 ATOM 3519 N N . GLU A 1 464 ? -108.921 5.171 306.140 1.00 43.93 ? 464 GLU A N 1 ATOM 3520 C CA . GLU A 1 464 ? -109.715 5.821 307.172 1.00 54.46 ? 464 GLU A CA 1 ATOM 3521 C C . GLU A 1 464 ? -111.052 5.105 307.276 1.00 51.11 ? 464 GLU A C 1 ATOM 3522 O O . GLU A 1 464 ? -111.705 4.856 306.258 1.00 58.61 ? 464 GLU A O 1 ATOM 3523 C CB . GLU A 1 464 ? -109.934 7.306 306.863 1.00 77.25 ? 464 GLU A CB 1 ATOM 3524 C CG . GLU A 1 464 ? -110.860 8.011 307.845 1.00 74.95 ? 464 GLU A CG 1 ATOM 3525 C CD . GLU A 1 464 ? -110.963 9.502 307.586 1.00 89.08 ? 464 GLU A CD 1 ATOM 3526 O OE1 . GLU A 1 464 ? -111.527 9.888 306.541 1.00 83.84 ? 464 GLU A OE1 1 ATOM 3527 O OE2 . GLU A 1 464 ? -110.481 10.288 308.429 1.00 108.17 ? 464 GLU A OE2 1 ATOM 3528 N N . ASP A 1 465 ? -111.449 4.765 308.499 1.00 52.50 ? 465 ASP A N 1 ATOM 3529 C CA . ASP A 1 465 ? -112.726 4.101 308.704 1.00 45.49 ? 465 ASP A CA 1 ATOM 3530 C C . ASP A 1 465 ? -113.877 5.023 308.316 1.00 46.04 ? 465 ASP A C 1 ATOM 3531 O O . ASP A 1 465 ? -113.825 6.241 308.510 1.00 45.67 ? 465 ASP A O 1 ATOM 3532 C CB . ASP A 1 465 ? -112.872 3.649 310.156 1.00 44.77 ? 465 ASP A CB 1 ATOM 3533 C CG . ASP A 1 465 ? -112.217 2.307 310.413 1.00 43.23 ? 465 ASP A CG 1 ATOM 3534 O OD1 . ASP A 1 465 ? -111.597 1.758 309.478 1.00 52.74 ? 465 ASP A OD1 1 ATOM 3535 O OD2 . ASP A 1 465 ? -112.323 1.799 311.548 1.00 43.22 ? 465 ASP A OD2 1 ATOM 3536 N N . GLY A 1 466 ? -114.925 4.423 307.756 1.00 55.08 ? 466 GLY A N 1 ATOM 3537 C CA . GLY A 1 466 ? -116.019 5.169 307.178 1.00 41.29 ? 466 GLY A CA 1 ATOM 3538 C C . GLY A 1 466 ? -115.883 5.433 305.695 1.00 38.43 ? 466 GLY A C 1 ATOM 3539 O O . GLY A 1 466 ? -116.864 5.845 305.063 1.00 42.88 ? 466 GLY A O 1 ATOM 3540 N N . VAL A 1 467 ? -114.701 5.217 305.123 1.00 32.84 ? 467 VAL A N 1 ATOM 3541 C CA . VAL A 1 467 ? -114.456 5.377 303.695 1.00 31.46 ? 467 VAL A CA 1 ATOM 3542 C C . VAL A 1 467 ? -113.682 4.159 303.212 1.00 33.73 ? 467 VAL A C 1 ATOM 3543 O O . VAL A 1 467 ? -112.690 3.764 303.833 1.00 35.49 ? 467 VAL A O 1 ATOM 3544 C CB . VAL A 1 467 ? -113.676 6.669 303.384 1.00 36.31 ? 467 VAL A CB 1 ATOM 3545 C CG1 . VAL A 1 467 ? -113.411 6.781 301.891 1.00 38.10 ? 467 VAL A CG1 1 ATOM 3546 C CG2 . VAL A 1 467 ? -114.434 7.888 303.884 1.00 47.27 ? 467 VAL A CG2 1 ATOM 3547 N N . VAL A 1 468 ? -114.133 3.565 302.110 1.00 33.86 ? 468 VAL A N 1 ATOM 3548 C CA . VAL A 1 468 ? -113.523 2.361 301.560 1.00 30.46 ? 468 VAL A CA 1 ATOM 3549 C C . VAL A 1 468 ? -113.156 2.625 300.107 1.00 27.20 ? 468 VAL A C 1 ATOM 3550 O O . VAL A 1 468 ? -113.989 3.106 299.331 1.00 25.05 ? 468 VAL A O 1 ATOM 3551 C CB . VAL A 1 468 ? -114.461 1.143 301.667 1.00 28.56 ? 468 VAL A CB 1 ATOM 3552 C CG1 . VAL A 1 468 ? -113.819 -0.079 301.033 1.00 36.05 ? 468 VAL A CG1 1 ATOM 3553 C CG2 . VAL A 1 468 ? -114.816 0.873 303.120 1.00 36.62 ? 468 VAL A CG2 1 ATOM 3554 N N . ASP A 1 469 ? -111.914 2.313 299.743 1.00 26.82 ? 469 ASP A N 1 ATOM 3555 C CA . ASP A 1 469 ? -111.487 2.451 298.359 1.00 26.62 ? 469 ASP A CA 1 ATOM 3556 C C . ASP A 1 469 ? -112.262 1.486 297.469 1.00 27.67 ? 469 ASP A C 1 ATOM 3557 O O . ASP A 1 469 ? -112.678 0.407 297.899 1.00 27.18 ? 469 ASP A O 1 ATOM 3558 C CB . ASP A 1 469 ? -109.986 2.184 298.227 1.00 25.22 ? 469 ASP A CB 1 ATOM 3559 C CG . ASP A 1 469 ? -109.142 3.224 298.935 1.00 25.71 ? 469 ASP A CG 1 ATOM 3560 O OD1 . ASP A 1 469 ? -109.397 4.432 298.748 1.00 40.94 ? 469 ASP A OD1 1 ATOM 3561 O OD2 . ASP A 1 469 ? -108.213 2.832 299.671 1.00 22.91 ? 469 ASP A OD2 1 ATOM 3562 N N . TYR A 1 470 ? -112.454 1.886 296.210 1.00 28.90 ? 470 TYR A N 1 ATOM 3563 C CA . TYR A 1 470 ? -113.175 1.030 295.274 1.00 30.27 ? 470 TYR A CA 1 ATOM 3564 C C . TYR A 1 470 ? -112.430 -0.273 295.017 1.00 28.58 ? 470 TYR A C 1 ATOM 3565 O O . TYR A 1 470 ? -113.059 -1.311 294.783 1.00 43.88 ? 470 TYR A O 1 ATOM 3566 C CB . TYR A 1 470 ? -113.417 1.770 293.957 1.00 32.77 ? 470 TYR A CB 1 ATOM 3567 C CG . TYR A 1 470 ? -113.935 0.879 292.850 1.00 31.43 ? 470 TYR A CG 1 ATOM 3568 C CD1 . TYR A 1 470 ? -115.276 0.529 292.787 1.00 31.05 ? 470 TYR A CD1 1 ATOM 3569 C CD2 . TYR A 1 470 ? -113.082 0.384 291.870 1.00 29.38 ? 470 TYR A CD2 1 ATOM 3570 C CE1 . TYR A 1 470 ? -115.754 -0.286 291.781 1.00 52.28 ? 470 TYR A CE1 1 ATOM 3571 C CE2 . TYR A 1 470 ? -113.552 -0.433 290.861 1.00 27.41 ? 470 TYR A CE2 1 ATOM 3572 C CZ . TYR A 1 470 ? -114.888 -0.765 290.822 1.00 32.51 ? 470 TYR A CZ 1 ATOM 3573 O OH . TYR A 1 470 ? -115.362 -1.578 289.819 1.00 45.69 ? 470 TYR A OH 1 ATOM 3574 N N . ARG A 1 471 ? -111.096 -0.239 295.055 1.00 25.04 ? 471 ARG A N 1 ATOM 3575 C CA . ARG A 1 471 ? -110.317 -1.444 294.789 1.00 24.94 ? 471 ARG A CA 1 ATOM 3576 C C . ARG A 1 471 ? -110.545 -2.501 295.862 1.00 33.97 ? 471 ARG A C 1 ATOM 3577 O O . ARG A 1 471 ? -110.679 -3.690 295.549 1.00 27.84 ? 471 ARG A O 1 ATOM 3578 C CB . ARG A 1 471 ? -108.833 -1.094 294.680 1.00 24.37 ? 471 ARG A CB 1 ATOM 3579 C CG . ARG A 1 471 ? -107.910 -2.299 294.634 1.00 24.72 ? 471 ARG A CG 1 ATOM 3580 C CD . ARG A 1 471 ? -106.501 -1.900 294.229 1.00 20.48 ? 471 ARG A CD 1 ATOM 3581 N NE . ARG A 1 471 ? -106.046 -0.698 294.921 1.00 20.49 ? 471 ARG A NE 1 ATOM 3582 C CZ . ARG A 1 471 ? -105.551 0.372 294.308 1.00 20.41 ? 471 ARG A CZ 1 ATOM 3583 N NH1 . ARG A 1 471 ? -105.442 0.390 292.986 1.00 17.25 ? 471 ARG A NH1 1 ATOM 3584 N NH2 . ARG A 1 471 ? -105.160 1.423 295.015 1.00 18.74 ? 471 ARG A NH2 1 ATOM 3585 N N . GLN A 1 472 ? -110.598 -2.090 297.130 1.00 29.78 ? 472 GLN A N 1 ATOM 3586 C CA . GLN A 1 472 ? -110.838 -3.049 298.203 1.00 28.13 ? 472 GLN A CA 1 ATOM 3587 C C . GLN A 1 472 ? -112.268 -3.574 298.169 1.00 28.34 ? 472 GLN A C 1 ATOM 3588 O O . GLN A 1 472 ? -112.525 -4.701 298.610 1.00 30.35 ? 472 GLN A O 1 ATOM 3589 C CB . GLN A 1 472 ? -110.527 -2.410 299.558 1.00 26.87 ? 472 GLN A CB 1 ATOM 3590 C CG . GLN A 1 472 ? -110.790 -3.311 300.755 1.00 28.64 ? 472 GLN A CG 1 ATOM 3591 C CD . GLN A 1 472 ? -110.693 -2.574 302.074 1.00 30.86 ? 472 GLN A CD 1 ATOM 3592 O OE1 . GLN A 1 472 ? -110.886 -1.361 302.136 1.00 29.81 ? 472 GLN A OE1 1 ATOM 3593 N NE2 . GLN A 1 472 ? -110.387 -3.306 303.139 1.00 51.97 ? 472 GLN A NE2 1 ATOM 3594 N N . ILE A 1 473 ? -113.206 -2.780 297.646 1.00 28.48 ? 473 ILE A N 1 ATOM 3595 C CA . ILE A 1 473 ? -114.584 -3.241 297.503 1.00 27.71 ? 473 ILE A CA 1 ATOM 3596 C C . ILE A 1 473 ? -114.644 -4.464 296.597 1.00 26.99 ? 473 ILE A C 1 ATOM 3597 O O . ILE A 1 473 ? -115.385 -5.418 296.863 1.00 31.60 ? 473 ILE A O 1 ATOM 3598 C CB . ILE A 1 473 ? -115.477 -2.101 296.977 1.00 34.62 ? 473 ILE A CB 1 ATOM 3599 C CG1 . ILE A 1 473 ? -115.596 -0.993 298.024 1.00 28.76 ? 473 ILE A CG1 1 ATOM 3600 C CG2 . ILE A 1 473 ? -116.853 -2.625 296.594 1.00 49.77 ? 473 ILE A CG2 1 ATOM 3601 C CD1 . ILE A 1 473 ? -116.443 0.177 297.582 1.00 30.37 ? 473 ILE A CD1 1 ATOM 3602 N N . GLN A 1 474 ? -113.857 -4.460 295.519 1.00 26.94 ? 474 GLN A N 1 ATOM 3603 C CA . GLN A 1 474 ? -113.845 -5.601 294.610 1.00 27.59 ? 474 GLN A CA 1 ATOM 3604 C C . GLN A 1 474 ? -113.244 -6.836 295.271 1.00 30.28 ? 474 GLN A C 1 ATOM 3605 O O . GLN A 1 474 ? -113.679 -7.961 295.001 1.00 30.64 ? 474 GLN A O 1 ATOM 3606 C CB . GLN A 1 474 ? -113.081 -5.245 293.335 1.00 29.24 ? 474 GLN A CB 1 ATOM 3607 C CG . GLN A 1 474 ? -113.729 -4.139 292.519 1.00 32.23 ? 474 GLN A CG 1 ATOM 3608 C CD . GLN A 1 474 ? -115.163 -4.457 292.145 1.00 36.21 ? 474 GLN A CD 1 ATOM 3609 O OE1 . GLN A 1 474 ? -115.497 -5.599 291.829 1.00 43.75 ? 474 GLN A OE1 1 ATOM 3610 N NE2 . GLN A 1 474 ? -116.022 -3.446 292.184 1.00 43.44 ? 474 GLN A NE2 1 ATOM 3611 N N . LYS A 1 475 ? -112.243 -6.649 296.135 1.00 29.18 ? 475 LYS A N 1 ATOM 3612 C CA . LYS A 1 475 ? -111.651 -7.791 296.827 1.00 31.32 ? 475 LYS A CA 1 ATOM 3613 C C . LYS A 1 475 ? -112.635 -8.413 297.809 1.00 33.84 ? 475 LYS A C 1 ATOM 3614 O O . LYS A 1 475 ? -112.740 -9.642 297.899 1.00 65.99 ? 475 LYS A O 1 ATOM 3615 C CB . LYS A 1 475 ? -110.372 -7.369 297.550 1.00 36.92 ? 475 LYS A CB 1 ATOM 3616 C CG . LYS A 1 475 ? -109.441 -6.488 296.729 1.00 50.23 ? 475 LYS A CG 1 ATOM 3617 C CD . LYS A 1 475 ? -108.056 -6.377 297.365 1.00 44.88 ? 475 LYS A CD 1 ATOM 3618 C CE . LYS A 1 475 ? -108.066 -6.756 298.841 1.00 46.34 ? 475 LYS A CE 1 ATOM 3619 N NZ . LYS A 1 475 ? -106.907 -6.181 299.577 1.00 70.70 ? 475 LYS A NZ 1 ATOM 3620 N N . ASP A 1 476 ? -113.362 -7.583 298.555 1.00 29.44 ? 476 ASP A N 1 ATOM 3621 C CA . ASP A 1 476 ? -114.348 -8.052 299.516 1.00 29.82 ? 476 ASP A CA 1 ATOM 3622 C C . ASP A 1 476 ? -115.741 -8.179 298.910 1.00 30.54 ? 476 ASP A C 1 ATOM 3623 O O . ASP A 1 476 ? -116.732 -8.163 299.648 1.00 33.87 ? 476 ASP A O 1 ATOM 3624 C CB . ASP A 1 476 ? -114.389 -7.113 300.724 1.00 30.18 ? 476 ASP A CB 1 ATOM 3625 C CG . ASP A 1 476 ? -113.026 -6.917 301.355 1.00 29.14 ? 476 ASP A CG 1 ATOM 3626 O OD1 . ASP A 1 476 ? -112.160 -7.802 301.190 1.00 33.12 ? 476 ASP A OD1 1 ATOM 3627 O OD2 . ASP A 1 476 ? -112.818 -5.877 302.014 1.00 28.02 ? 476 ASP A OD2 1 ATOM 3628 N N . LEU A 1 477 ? -115.835 -8.316 297.585 1.00 27.87 ? 477 LEU A N 1 ATOM 3629 C CA . LEU A 1 477 ? -117.131 -8.248 296.917 1.00 30.74 ? 477 LEU A CA 1 ATOM 3630 C C . LEU A 1 477 ? -118.032 -9.419 297.289 1.00 31.53 ? 477 LEU A C 1 ATOM 3631 O O . LEU A 1 477 ? -119.259 -9.271 297.306 1.00 34.89 ? 477 LEU A O 1 ATOM 3632 C CB . LEU A 1 477 ? -116.933 -8.185 295.402 1.00 39.98 ? 477 LEU A CB 1 ATOM 3633 C CG . LEU A 1 477 ? -118.177 -7.963 294.540 1.00 25.16 ? 477 LEU A CG 1 ATOM 3634 C CD1 . LEU A 1 477 ? -118.921 -6.718 294.992 1.00 25.41 ? 477 LEU A CD1 1 ATOM 3635 C CD2 . LEU A 1 477 ? -117.797 -7.861 293.072 1.00 25.81 ? 477 LEU A CD2 1 ATOM 3636 N N . ASN A 1 478 ? -117.457 -10.581 297.591 1.00 32.87 ? 478 ASN A N 1 ATOM 3637 C CA . ASN A 1 478 ? -118.242 -11.748 297.971 1.00 35.21 ? 478 ASN A CA 1 ATOM 3638 C C . ASN A 1 478 ? -118.519 -11.814 299.469 1.00 37.00 ? 478 ASN A C 1 ATOM 3639 O O . ASN A 1 478 ? -119.052 -12.821 299.944 1.00 44.88 ? 478 ASN A O 1 ATOM 3640 C CB . ASN A 1 478 ? -117.549 -13.029 297.503 1.00 39.28 ? 478 ASN A CB 1 ATOM 3641 C CG . ASN A 1 478 ? -117.412 -13.092 295.995 1.00 59.69 ? 478 ASN A CG 1 ATOM 3642 O OD1 . ASN A 1 478 ? -118.202 -12.492 295.266 1.00 46.11 ? 478 ASN A OD1 1 ATOM 3643 N ND2 . ASN A 1 478 ? -116.409 -13.820 295.520 1.00 61.14 ? 478 ASN A ND2 1 ATOM 3644 N N . ASN A 1 479 ? -118.165 -10.771 300.219 1.00 33.10 ? 479 ASN A N 1 ATOM 3645 C CA . ASN A 1 479 ? -118.638 -10.609 301.586 1.00 34.04 ? 479 ASN A CA 1 ATOM 3646 C C . ASN A 1 479 ? -119.869 -9.718 301.673 1.00 46.79 ? 479 ASN A C 1 ATOM 3647 O O . ASN A 1 479 ? -120.492 -9.648 302.738 1.00 48.33 ? 479 ASN A O 1 ATOM 3648 C CB . ASN A 1 479 ? -117.529 -10.032 302.477 1.00 42.20 ? 479 ASN A CB 1 ATOM 3649 C CG . ASN A 1 479 ? -116.273 -10.879 302.466 1.00 39.32 ? 479 ASN A CG 1 ATOM 3650 O OD1 . ASN A 1 479 ? -116.326 -12.083 302.217 1.00 39.10 ? 479 ASN A OD1 1 ATOM 3651 N ND2 . ASN A 1 479 ? -115.135 -10.253 302.742 1.00 51.68 ? 479 ASN A ND2 1 ATOM 3652 N N . TYR A 1 480 ? -120.231 -9.044 300.586 1.00 34.78 ? 480 TYR A N 1 ATOM 3653 C CA . TYR A 1 480 ? -121.390 -8.169 300.534 1.00 34.22 ? 480 TYR A CA 1 ATOM 3654 C C . TYR A 1 480 ? -122.379 -8.689 299.499 1.00 30.48 ? 480 TYR A C 1 ATOM 3655 O O . TYR A 1 480 ? -122.088 -9.609 298.729 1.00 28.56 ? 480 TYR A O 1 ATOM 3656 C CB . TYR A 1 480 ? -120.984 -6.731 300.188 1.00 44.72 ? 480 TYR A CB 1 ATOM 3657 C CG . TYR A 1 480 ? -119.880 -6.155 301.046 1.00 33.63 ? 480 TYR A CG 1 ATOM 3658 C CD1 . TYR A 1 480 ? -120.115 -5.792 302.364 1.00 41.62 ? 480 TYR A CD1 1 ATOM 3659 C CD2 . TYR A 1 480 ? -118.608 -5.955 300.528 1.00 30.40 ? 480 TYR A CD2 1 ATOM 3660 C CE1 . TYR A 1 480 ? -119.108 -5.260 303.148 1.00 49.78 ? 480 TYR A CE1 1 ATOM 3661 C CE2 . TYR A 1 480 ? -117.595 -5.425 301.303 1.00 29.44 ? 480 TYR A CE2 1 ATOM 3662 C CZ . TYR A 1 480 ? -117.850 -5.079 302.612 1.00 34.63 ? 480 TYR A CZ 1 ATOM 3663 O OH . TYR A 1 480 ? -116.845 -4.549 303.387 1.00 34.57 ? 480 TYR A OH 1 ATOM 3664 N N . VAL A 1 481 ? -123.560 -8.081 299.484 1.00 31.31 ? 481 VAL A N 1 ATOM 3665 C CA . VAL A 1 481 ? -124.593 -8.369 298.495 1.00 29.15 ? 481 VAL A CA 1 ATOM 3666 C C . VAL A 1 481 ? -124.755 -7.121 297.639 1.00 28.05 ? 481 VAL A C 1 ATOM 3667 O O . VAL A 1 481 ? -125.211 -6.077 298.123 1.00 27.70 ? 481 VAL A O 1 ATOM 3668 C CB . VAL A 1 481 ? -125.920 -8.776 299.150 1.00 29.10 ? 481 VAL A CB 1 ATOM 3669 C CG1 . VAL A 1 481 ? -127.030 -8.824 298.112 1.00 29.84 ? 481 VAL A CG1 1 ATOM 3670 C CG2 . VAL A 1 481 ? -125.775 -10.122 299.844 1.00 33.00 ? 481 VAL A CG2 1 ATOM 3671 N N . TYR A 1 482 ? -124.378 -7.224 296.368 1.00 29.10 ? 482 TYR A N 1 ATOM 3672 C CA . TYR A 1 482 ? -124.402 -6.070 295.480 1.00 28.66 ? 482 TYR A CA 1 ATOM 3673 C C . TYR A 1 482 ? -125.833 -5.701 295.113 1.00 30.41 ? 482 TYR A C 1 ATOM 3674 O O . TYR A 1 482 ? -126.696 -6.568 294.951 1.00 30.92 ? 482 TYR A O 1 ATOM 3675 C CB . TYR A 1 482 ? -123.590 -6.361 294.217 1.00 32.57 ? 482 TYR A CB 1 ATOM 3676 C CG . TYR A 1 482 ? -123.592 -5.241 293.201 1.00 32.87 ? 482 TYR A CG 1 ATOM 3677 C CD1 . TYR A 1 482 ? -122.711 -4.174 293.315 1.00 35.36 ? 482 TYR A CD1 1 ATOM 3678 C CD2 . TYR A 1 482 ? -124.465 -5.256 292.120 1.00 41.20 ? 482 TYR A CD2 1 ATOM 3679 C CE1 . TYR A 1 482 ? -122.705 -3.149 292.388 1.00 37.38 ? 482 TYR A CE1 1 ATOM 3680 C CE2 . TYR A 1 482 ? -124.466 -4.236 291.187 1.00 43.44 ? 482 TYR A CE2 1 ATOM 3681 C CZ . TYR A 1 482 ? -123.584 -3.186 291.326 1.00 37.72 ? 482 TYR A CZ 1 ATOM 3682 O OH . TYR A 1 482 ? -123.581 -2.168 290.400 1.00 33.77 ? 482 TYR A OH 1 ATOM 3683 N N . THR A 1 483 ? -126.081 -4.399 294.982 1.00 36.45 ? 483 THR A N 1 ATOM 3684 C CA . THR A 1 483 ? -127.395 -3.899 294.599 1.00 38.65 ? 483 THR A CA 1 ATOM 3685 C C . THR A 1 483 ? -127.221 -2.615 293.804 1.00 36.11 ? 483 THR A C 1 ATOM 3686 O O . THR A 1 483 ? -126.565 -1.679 294.269 1.00 34.03 ? 483 THR A O 1 ATOM 3687 C CB . THR A 1 483 ? -128.278 -3.643 295.825 1.00 30.39 ? 483 THR A CB 1 ATOM 3688 O OG1 . THR A 1 483 ? -128.407 -4.851 296.585 1.00 32.10 ? 483 THR A OG1 1 ATOM 3689 C CG2 . THR A 1 483 ? -129.659 -3.177 295.391 1.00 35.24 ? 483 THR A CG2 1 ATOM 3690 N N . PHE A 1 484 ? -127.807 -2.578 292.613 1.00 38.11 ? 484 PHE A N 1 ATOM 3691 C CA . PHE A 1 484 ? -127.770 -1.413 291.741 1.00 39.63 ? 484 PHE A CA 1 ATOM 3692 C C . PHE A 1 484 ? -129.154 -0.782 291.702 1.00 43.24 ? 484 PHE A C 1 ATOM 3693 O O . PHE A 1 484 ? -130.153 -1.485 291.522 1.00 61.76 ? 484 PHE A O 1 ATOM 3694 C CB . PHE A 1 484 ? -127.314 -1.803 290.333 1.00 40.07 ? 484 PHE A CB 1 ATOM 3695 C CG . PHE A 1 484 ? -127.250 -0.651 289.370 1.00 36.20 ? 484 PHE A CG 1 ATOM 3696 C CD1 . PHE A 1 484 ? -126.384 0.407 289.590 1.00 36.48 ? 484 PHE A CD1 1 ATOM 3697 C CD2 . PHE A 1 484 ? -128.043 -0.635 288.236 1.00 34.45 ? 484 PHE A CD2 1 ATOM 3698 C CE1 . PHE A 1 484 ? -126.320 1.466 288.704 1.00 35.60 ? 484 PHE A CE1 1 ATOM 3699 C CE2 . PHE A 1 484 ? -127.982 0.419 287.344 1.00 43.32 ? 484 PHE A CE2 1 ATOM 3700 C CZ . PHE A 1 484 ? -127.119 1.471 287.579 1.00 40.87 ? 484 PHE A CZ 1 ATOM 3701 N N . ASP A 1 485 ? -129.215 0.534 291.883 1.00 40.94 ? 485 ASP A N 1 ATOM 3702 C CA . ASP A 1 485 ? -130.480 1.267 291.878 1.00 30.33 ? 485 ASP A CA 1 ATOM 3703 C C . ASP A 1 485 ? -130.619 1.901 290.497 1.00 33.10 ? 485 ASP A C 1 ATOM 3704 O O . ASP A 1 485 ? -130.238 3.051 290.279 1.00 47.77 ? 485 ASP A O 1 ATOM 3705 C CB . ASP A 1 485 ? -130.513 2.302 292.998 1.00 27.95 ? 485 ASP A CB 1 ATOM 3706 C CG . ASP A 1 485 ? -131.887 2.921 293.191 1.00 29.28 ? 485 ASP A CG 1 ATOM 3707 O OD1 . ASP A 1 485 ? -132.676 2.973 292.225 1.00 31.98 ? 485 ASP A OD1 1 ATOM 3708 O OD2 . ASP A 1 485 ? -132.179 3.359 294.324 1.00 28.58 ? 485 ASP A OD2 1 ATOM 3709 N N . SER A 1 486 ? -131.180 1.135 289.558 1.00 31.36 ? 486 SER A N 1 ATOM 3710 C CA . SER A 1 486 ? -131.300 1.590 288.177 1.00 35.95 ? 486 SER A CA 1 ATOM 3711 C C . SER A 1 486 ? -132.184 2.820 288.028 1.00 37.80 ? 486 SER A C 1 ATOM 3712 O O . SER A 1 486 ? -132.151 3.459 286.971 1.00 45.23 ? 486 SER A O 1 ATOM 3713 C CB . SER A 1 486 ? -131.838 0.457 287.300 1.00 38.44 ? 486 SER A CB 1 ATOM 3714 O OG . SER A 1 486 ? -133.099 0.007 287.763 1.00 45.24 ? 486 SER A OG 1 ATOM 3715 N N . ALA A 1 487 ? -132.972 3.166 289.047 1.00 38.11 ? 487 ALA A N 1 ATOM 3716 C CA . ALA A 1 487 ? -133.760 4.391 288.988 1.00 35.80 ? 487 ALA A CA 1 ATOM 3717 C C . ALA A 1 487 ? -132.911 5.612 289.318 1.00 33.12 ? 487 ALA A C 1 ATOM 3718 O O . ALA A 1 487 ? -133.024 6.648 288.653 1.00 33.25 ? 487 ALA A O 1 ATOM 3719 C CB . ALA A 1 487 ? -134.952 4.296 289.941 1.00 37.78 ? 487 ALA A CB 1 ATOM 3720 N N . ALA A 1 488 ? -132.055 5.506 290.333 1.00 35.39 ? 488 ALA A N 1 ATOM 3721 C CA . ALA A 1 488 ? -131.198 6.605 290.753 1.00 37.78 ? 488 ALA A CA 1 ATOM 3722 C C . ALA A 1 488 ? -129.811 6.558 290.129 1.00 40.57 ? 488 ALA A C 1 ATOM 3723 O O . ALA A 1 488 ? -129.043 7.511 290.304 1.00 36.28 ? 488 ALA A O 1 ATOM 3724 C CB . ALA A 1 488 ? -131.058 6.613 292.278 1.00 32.97 ? 488 ALA A CB 1 ATOM 3725 N N . GLN A 1 489 ? -129.476 5.480 289.417 1.00 35.53 ? 489 GLN A N 1 ATOM 3726 C CA . GLN A 1 489 ? -128.147 5.291 288.833 1.00 32.91 ? 489 GLN A CA 1 ATOM 3727 C C . GLN A 1 489 ? -127.068 5.309 289.915 1.00 28.39 ? 489 GLN A C 1 ATOM 3728 O O . GLN A 1 489 ? -126.087 6.051 289.838 1.00 28.55 ? 489 GLN A O 1 ATOM 3729 C CB . GLN A 1 489 ? -127.863 6.339 287.752 1.00 29.18 ? 489 GLN A CB 1 ATOM 3730 C CG . GLN A 1 489 ? -128.844 6.330 286.590 1.00 28.16 ? 489 GLN A CG 1 ATOM 3731 C CD . GLN A 1 489 ? -128.503 5.294 285.538 1.00 30.15 ? 489 GLN A CD 1 ATOM 3732 O OE1 . GLN A 1 489 ? -128.131 4.164 285.855 1.00 35.28 ? 489 GLN A OE1 1 ATOM 3733 N NE2 . GLN A 1 489 ? -128.626 5.677 284.272 1.00 30.51 ? 489 GLN A NE2 1 ATOM 3734 N N . ALA A 1 490 ? -127.262 4.480 290.938 1.00 26.59 ? 490 ALA A N 1 ATOM 3735 C CA . ALA A 1 490 ? -126.321 4.375 292.043 1.00 29.61 ? 490 ALA A CA 1 ATOM 3736 C C . ALA A 1 490 ? -126.203 2.918 292.465 1.00 32.26 ? 490 ALA A C 1 ATOM 3737 O O . ALA A 1 490 ? -127.051 2.084 292.140 1.00 31.66 ? 490 ALA A O 1 ATOM 3738 C CB . ALA A 1 490 ? -126.747 5.239 293.236 1.00 28.47 ? 490 ALA A CB 1 ATOM 3739 N N . SER A 1 491 ? -125.136 2.621 293.203 1.00 32.44 ? 491 SER A N 1 ATOM 3740 C CA . SER A 1 491 ? -124.854 1.270 293.658 1.00 33.65 ? 491 SER A CA 1 ATOM 3741 C C . SER A 1 491 ? -124.519 1.281 295.141 1.00 34.38 ? 491 SER A C 1 ATOM 3742 O O . SER A 1 491 ? -124.058 2.289 295.684 1.00 35.09 ? 491 SER A O 1 ATOM 3743 C CB . SER A 1 491 ? -123.692 0.643 292.874 1.00 45.32 ? 491 SER A CB 1 ATOM 3744 O OG . SER A 1 491 ? -123.947 0.653 291.482 1.00 42.78 ? 491 SER A OG 1 ATOM 3745 N N . TYR A 1 492 ? -124.759 0.146 295.792 1.00 31.26 ? 492 TYR A N 1 ATOM 3746 C CA . TYR A 1 492 ? -124.380 -0.035 297.186 1.00 29.65 ? 492 TYR A CA 1 ATOM 3747 C C . TYR A 1 492 ? -124.284 -1.527 297.466 1.00 33.89 ? 492 TYR A C 1 ATOM 3748 O O . TYR A 1 492 ? -124.733 -2.360 296.675 1.00 39.21 ? 492 TYR A O 1 ATOM 3749 C CB . TYR A 1 492 ? -125.367 0.647 298.139 1.00 29.98 ? 492 TYR A CB 1 ATOM 3750 C CG . TYR A 1 492 ? -126.779 0.111 298.076 1.00 34.35 ? 492 TYR A CG 1 ATOM 3751 C CD1 . TYR A 1 492 ? -127.684 0.592 297.140 1.00 38.60 ? 492 TYR A CD1 1 ATOM 3752 C CD2 . TYR A 1 492 ? -127.211 -0.867 298.962 1.00 32.54 ? 492 TYR A CD2 1 ATOM 3753 C CE1 . TYR A 1 492 ? -128.976 0.109 297.082 1.00 31.19 ? 492 TYR A CE1 1 ATOM 3754 C CE2 . TYR A 1 492 ? -128.501 -1.357 298.911 1.00 33.92 ? 492 TYR A CE2 1 ATOM 3755 C CZ . TYR A 1 492 ? -129.379 -0.865 297.970 1.00 31.69 ? 492 TYR A CZ 1 ATOM 3756 O OH . TYR A 1 492 ? -130.666 -1.349 297.915 1.00 32.90 ? 492 TYR A OH 1 ATOM 3757 N N . VAL A 1 493 ? -123.686 -1.854 298.609 1.00 34.05 ? 493 VAL A N 1 ATOM 3758 C CA . VAL A 1 493 ? -123.482 -3.236 299.024 1.00 32.23 ? 493 VAL A CA 1 ATOM 3759 C C . VAL A 1 493 ? -123.851 -3.363 300.494 1.00 33.49 ? 493 VAL A C 1 ATOM 3760 O O . VAL A 1 493 ? -123.794 -2.391 301.254 1.00 33.07 ? 493 VAL A O 1 ATOM 3761 C CB . VAL A 1 493 ? -122.030 -3.699 298.780 1.00 31.53 ? 493 VAL A CB 1 ATOM 3762 C CG1 . VAL A 1 493 ? -121.761 -3.857 297.292 1.00 32.69 ? 493 VAL A CG1 1 ATOM 3763 C CG2 . VAL A 1 493 ? -121.048 -2.721 299.406 1.00 46.98 ? 493 VAL A CG2 1 ATOM 3764 N N . PHE A 1 494 ? -124.231 -4.575 300.897 1.00 33.39 ? 494 PHE A N 1 ATOM 3765 C CA . PHE A 1 494 ? -124.675 -4.821 302.260 1.00 37.43 ? 494 PHE A CA 1 ATOM 3766 C C . PHE A 1 494 ? -124.196 -6.188 302.726 1.00 36.84 ? 494 PHE A C 1 ATOM 3767 O O . PHE A 1 494 ? -124.120 -7.138 301.943 1.00 35.49 ? 494 PHE A O 1 ATOM 3768 C CB . PHE A 1 494 ? -126.203 -4.738 302.379 1.00 41.11 ? 494 PHE A CB 1 ATOM 3769 C CG . PHE A 1 494 ? -126.703 -4.815 303.792 1.00 43.59 ? 494 PHE A CG 1 ATOM 3770 C CD1 . PHE A 1 494 ? -126.613 -3.717 304.631 1.00 48.88 ? 494 PHE A CD1 1 ATOM 3771 C CD2 . PHE A 1 494 ? -127.263 -5.982 304.282 1.00 51.30 ? 494 PHE A CD2 1 ATOM 3772 C CE1 . PHE A 1 494 ? -127.071 -3.782 305.933 1.00 56.76 ? 494 PHE A CE1 1 ATOM 3773 C CE2 . PHE A 1 494 ? -127.723 -6.051 305.584 1.00 51.86 ? 494 PHE A CE2 1 ATOM 3774 C CZ . PHE A 1 494 ? -127.627 -4.951 306.410 1.00 57.28 ? 494 PHE A CZ 1 ATOM 3775 N N . ASP A 1 495 ? -123.880 -6.273 304.017 1.00 39.22 ? 495 ASP A N 1 ATOM 3776 C CA . ASP A 1 495 ? -123.435 -7.514 304.647 1.00 43.38 ? 495 ASP A CA 1 ATOM 3777 C C . ASP A 1 495 ? -124.151 -7.640 305.984 1.00 50.42 ? 495 ASP A C 1 ATOM 3778 O O . ASP A 1 495 ? -123.844 -6.901 306.924 1.00 49.88 ? 495 ASP A O 1 ATOM 3779 C CB . ASP A 1 495 ? -121.918 -7.528 304.836 1.00 44.64 ? 495 ASP A CB 1 ATOM 3780 C CG . ASP A 1 495 ? -121.422 -8.804 305.485 1.00 52.17 ? 495 ASP A CG 1 ATOM 3781 O OD1 . ASP A 1 495 ? -122.137 -9.826 305.420 1.00 76.84 ? 495 ASP A OD1 1 ATOM 3782 O OD2 . ASP A 1 495 ? -120.314 -8.784 306.062 1.00 58.55 ? 495 ASP A OD2 1 ATOM 3783 N N . LYS A 1 496 ? -125.097 -8.577 306.071 1.00 59.40 ? 496 LYS A N 1 ATOM 3784 C CA . LYS A 1 496 ? -125.893 -8.735 307.283 1.00 58.74 ? 496 LYS A CA 1 ATOM 3785 C C . LYS A 1 496 ? -125.099 -9.309 308.450 1.00 54.80 ? 496 LYS A C 1 ATOM 3786 O O . LYS A 1 496 ? -125.599 -9.289 309.580 1.00 54.25 ? 496 LYS A O 1 ATOM 3787 C CB . LYS A 1 496 ? -127.105 -9.625 307.004 1.00 68.38 ? 496 LYS A CB 1 ATOM 3788 C CG . LYS A 1 496 ? -127.641 -9.525 305.587 1.00 65.86 ? 496 LYS A CG 1 ATOM 3789 C CD . LYS A 1 496 ? -128.963 -10.262 305.445 1.00 80.20 ? 496 LYS A CD 1 ATOM 3790 C CE . LYS A 1 496 ? -130.079 -9.534 306.180 1.00 95.35 ? 496 LYS A CE 1 ATOM 3791 N NZ . LYS A 1 496 ? -131.341 -9.499 305.390 1.00 82.53 ? 496 LYS A NZ 1 ATOM 3792 N N . SER A 1 497 ? -123.889 -9.818 308.212 1.00 56.89 ? 497 SER A N 1 ATOM 3793 C CA . SER A 1 497 ? -123.101 -10.390 309.300 1.00 57.32 ? 497 SER A CA 1 ATOM 3794 C C . SER A 1 497 ? -122.677 -9.316 310.294 1.00 56.68 ? 497 SER A C 1 ATOM 3795 O O . SER A 1 497 ? -122.837 -9.482 311.509 1.00 73.58 ? 497 SER A O 1 ATOM 3796 C CB . SER A 1 497 ? -121.881 -11.119 308.738 1.00 62.06 ? 497 SER A CB 1 ATOM 3797 O OG . SER A 1 497 ? -120.970 -10.210 308.148 1.00 65.29 ? 497 SER A OG 1 ATOM 3798 N N . LYS A 1 498 ? -122.134 -8.204 309.797 1.00 58.11 ? 498 LYS A N 1 ATOM 3799 C CA . LYS A 1 498 ? -121.721 -7.094 310.646 1.00 66.19 ? 498 LYS A CA 1 ATOM 3800 C C . LYS A 1 498 ? -122.480 -5.808 310.339 1.00 50.86 ? 498 LYS A C 1 ATOM 3801 O O . LYS A 1 498 ? -122.135 -4.753 310.883 1.00 55.19 ? 498 LYS A O 1 ATOM 3802 C CB . LYS A 1 498 ? -120.212 -6.855 310.520 1.00 60.60 ? 498 LYS A CB 1 ATOM 3803 C CG . LYS A 1 498 ? -119.413 -8.073 310.077 1.00 53.91 ? 498 LYS A CG 1 ATOM 3804 C CD . LYS A 1 498 ? -119.267 -9.080 311.208 1.00 58.90 ? 498 LYS A CD 1 ATOM 3805 C CE . LYS A 1 498 ? -118.364 -10.236 310.809 1.00 52.88 ? 498 LYS A CE 1 ATOM 3806 N NZ . LYS A 1 498 ? -118.176 -11.209 311.921 1.00 46.47 ? 498 LYS A NZ 1 ATOM 3807 N N . GLY A 1 499 ? -123.499 -5.867 309.488 1.00 48.71 ? 499 GLY A N 1 ATOM 3808 C CA . GLY A 1 499 ? -124.291 -4.688 309.175 1.00 52.46 ? 499 GLY A CA 1 ATOM 3809 C C . GLY A 1 499 ? -123.550 -3.622 308.398 1.00 58.65 ? 499 GLY A C 1 ATOM 3810 O O . GLY A 1 499 ? -123.777 -2.426 308.624 1.00 57.62 ? 499 GLY A O 1 ATOM 3811 N N . ASP A 1 500 ? -122.671 -4.023 307.483 1.00 54.71 ? 500 ASP A N 1 ATOM 3812 C CA . ASP A 1 500 ? -121.866 -3.084 306.709 1.00 40.85 ? 500 ASP A CA 1 ATOM 3813 C C . ASP A 1 500 ? -122.634 -2.692 305.451 1.00 38.36 ? 500 ASP A C 1 ATOM 3814 O O . ASP A 1 500 ? -122.835 -3.517 304.555 1.00 40.70 ? 500 ASP A O 1 ATOM 3815 C CB . ASP A 1 500 ? -120.513 -3.696 306.358 1.00 42.96 ? 500 ASP A CB 1 ATOM 3816 C CG . ASP A 1 500 ? -119.645 -3.927 307.579 1.00 52.35 ? 500 ASP A CG 1 ATOM 3817 O OD1 . ASP A 1 500 ? -119.690 -3.093 308.507 1.00 48.89 ? 500 ASP A OD1 1 ATOM 3818 O OD2 . ASP A 1 500 ? -118.916 -4.941 307.608 1.00 55.53 ? 500 ASP A OD2 1 ATOM 3819 N N . LEU A 1 501 ? -123.060 -1.432 305.385 1.00 36.28 ? 501 LEU A N 1 ATOM 3820 C CA . LEU A 1 501 ? -123.790 -0.891 304.242 1.00 36.99 ? 501 LEU A CA 1 ATOM 3821 C C . LEU A 1 501 ? -122.964 0.241 303.646 1.00 38.14 ? 501 LEU A C 1 ATOM 3822 O O . LEU A 1 501 ? -122.846 1.309 304.253 1.00 36.54 ? 501 LEU A O 1 ATOM 3823 C CB . LEU A 1 501 ? -125.174 -0.399 304.661 1.00 41.59 ? 501 LEU A CB 1 ATOM 3824 C CG . LEU A 1 501 ? -125.946 0.434 303.636 1.00 37.02 ? 501 LEU A CG 1 ATOM 3825 C CD1 . LEU A 1 501 ? -126.311 -0.403 302.421 1.00 40.86 ? 501 LEU A CD1 1 ATOM 3826 C CD2 . LEU A 1 501 ? -127.186 1.040 304.271 1.00 42.95 ? 501 LEU A CD2 1 ATOM 3827 N N . ILE A 1 502 ? -122.408 0.014 302.459 1.00 38.78 ? 502 ILE A N 1 ATOM 3828 C CA . ILE A 1 502 ? -121.468 0.937 301.831 1.00 38.43 ? 502 ILE A CA 1 ATOM 3829 C C . ILE A 1 502 ? -122.050 1.410 300.507 1.00 32.59 ? 502 ILE A C 1 ATOM 3830 O O . ILE A 1 502 ? -122.479 0.592 299.685 1.00 31.37 ? 502 ILE A O 1 ATOM 3831 C CB . ILE A 1 502 ? -120.093 0.280 301.617 1.00 37.88 ? 502 ILE A CB 1 ATOM 3832 C CG1 . ILE A 1 502 ? -119.490 -0.140 302.959 1.00 34.00 ? 502 ILE A CG1 1 ATOM 3833 C CG2 . ILE A 1 502 ? -119.157 1.223 300.878 1.00 38.47 ? 502 ILE A CG2 1 ATOM 3834 C CD1 . ILE A 1 502 ? -118.241 -0.978 302.827 1.00 34.19 ? 502 ILE A CD1 1 ATOM 3835 N N . SER A 1 503 ? -122.055 2.724 300.300 1.00 32.32 ? 503 SER A N 1 ATOM 3836 C CA . SER A 1 503 ? -122.500 3.335 299.054 1.00 30.33 ? 503 SER A CA 1 ATOM 3837 C C . SER A 1 503 ? -121.290 3.845 298.286 1.00 29.89 ? 503 SER A C 1 ATOM 3838 O O . SER A 1 503 ? -120.470 4.586 298.837 1.00 33.67 ? 503 SER A O 1 ATOM 3839 C CB . SER A 1 503 ? -123.477 4.482 299.322 1.00 26.76 ? 503 SER A CB 1 ATOM 3840 O OG . SER A 1 503 ? -123.716 5.229 298.142 1.00 27.81 ? 503 SER A OG 1 ATOM 3841 N N . PHE A 1 504 ? -121.185 3.457 297.018 1.00 30.38 ? 504 PHE A N 1 ATOM 3842 C CA . PHE A 1 504 ? -120.024 3.797 296.206 1.00 31.81 ? 504 PHE A CA 1 ATOM 3843 C C . PHE A 1 504 ? -120.457 3.907 294.748 1.00 31.24 ? 504 PHE A C 1 ATOM 3844 O O . PHE A 1 504 ? -121.647 3.837 294.426 1.00 30.00 ? 504 PHE A O 1 ATOM 3845 C CB . PHE A 1 504 ? -118.910 2.760 296.400 1.00 28.26 ? 504 PHE A CB 1 ATOM 3846 C CG . PHE A 1 504 ? -119.241 1.400 295.852 1.00 31.21 ? 504 PHE A CG 1 ATOM 3847 C CD1 . PHE A 1 504 ? -120.010 0.511 296.584 1.00 32.22 ? 504 PHE A CD1 1 ATOM 3848 C CD2 . PHE A 1 504 ? -118.776 1.006 294.608 1.00 34.34 ? 504 PHE A CD2 1 ATOM 3849 C CE1 . PHE A 1 504 ? -120.315 -0.740 296.085 1.00 31.91 ? 504 PHE A CE1 1 ATOM 3850 C CE2 . PHE A 1 504 ? -119.077 -0.245 294.102 1.00 32.90 ? 504 PHE A CE2 1 ATOM 3851 C CZ . PHE A 1 504 ? -119.847 -1.119 294.842 1.00 29.98 ? 504 PHE A CZ 1 ATOM 3852 N N . ASP A 1 505 ? -119.478 4.084 293.862 1.00 31.38 ? 505 ASP A N 1 ATOM 3853 C CA . ASP A 1 505 ? -119.702 4.169 292.423 1.00 32.54 ? 505 ASP A CA 1 ATOM 3854 C C . ASP A 1 505 ? -119.111 2.928 291.768 1.00 33.96 ? 505 ASP A C 1 ATOM 3855 O O . ASP A 1 505 ? -117.889 2.739 291.772 1.00 41.60 ? 505 ASP A O 1 ATOM 3856 C CB . ASP A 1 505 ? -119.078 5.437 291.842 1.00 31.27 ? 505 ASP A CB 1 ATOM 3857 C CG . ASP A 1 505 ? -120.095 6.533 291.606 1.00 35.63 ? 505 ASP A CG 1 ATOM 3858 O OD1 . ASP A 1 505 ? -121.302 6.220 291.534 1.00 44.29 ? 505 ASP A OD1 1 ATOM 3859 O OD2 . ASP A 1 505 ? -119.688 7.707 291.485 1.00 34.48 ? 505 ASP A OD2 1 ATOM 3860 N N . SER A 1 506 ? -119.974 2.086 291.208 1.00 31.00 ? 506 SER A N 1 ATOM 3861 C CA . SER A 1 506 ? -119.534 0.907 290.483 1.00 29.74 ? 506 SER A CA 1 ATOM 3862 C C . SER A 1 506 ? -119.421 1.231 288.995 1.00 29.70 ? 506 SER A C 1 ATOM 3863 O O . SER A 1 506 ? -119.600 2.372 288.566 1.00 30.19 ? 506 SER A O 1 ATOM 3864 C CB . SER A 1 506 ? -120.494 -0.256 290.723 1.00 38.80 ? 506 SER A CB 1 ATOM 3865 O OG . SER A 1 506 ? -121.768 0.012 290.164 1.00 37.70 ? 506 SER A OG 1 ATOM 3866 N N . VAL A 1 507 ? -119.116 0.209 288.193 1.00 32.11 ? 507 VAL A N 1 ATOM 3867 C CA . VAL A 1 507 ? -119.043 0.404 286.748 1.00 33.58 ? 507 VAL A CA 1 ATOM 3868 C C . VAL A 1 507 ? -120.415 0.764 286.193 1.00 37.79 ? 507 VAL A C 1 ATOM 3869 O O . VAL A 1 507 ? -120.533 1.556 285.250 1.00 35.08 ? 507 VAL A O 1 ATOM 3870 C CB . VAL A 1 507 ? -118.467 -0.853 286.068 1.00 36.12 ? 507 VAL A CB 1 ATOM 3871 C CG1 . VAL A 1 507 ? -118.310 -0.627 284.571 1.00 35.92 ? 507 VAL A CG1 1 ATOM 3872 C CG2 . VAL A 1 507 ? -117.138 -1.235 286.700 1.00 79.00 ? 507 VAL A CG2 1 ATOM 3873 N N . ASP A 1 508 ? -121.473 0.198 286.779 1.00 34.77 ? 508 ASP A N 1 ATOM 3874 C CA . ASP A 1 508 ? -122.826 0.485 286.313 1.00 33.69 ? 508 ASP A CA 1 ATOM 3875 C C . ASP A 1 508 ? -123.186 1.948 286.537 1.00 37.76 ? 508 ASP A C 1 ATOM 3876 O O . ASP A 1 508 ? -123.648 2.634 285.618 1.00 46.11 ? 508 ASP A O 1 ATOM 3877 C CB . ASP A 1 508 ? -123.826 -0.428 287.024 1.00 33.01 ? 508 ASP A CB 1 ATOM 3878 C CG . ASP A 1 508 ? -123.578 -1.897 286.746 1.00 33.94 ? 508 ASP A CG 1 ATOM 3879 O OD1 . ASP A 1 508 ? -123.153 -2.228 285.619 1.00 36.01 ? 508 ASP A OD1 1 ATOM 3880 O OD2 . ASP A 1 508 ? -123.806 -2.720 287.657 1.00 32.78 ? 508 ASP A OD2 1 ATOM 3881 N N . SER A 1 509 ? -122.978 2.444 287.759 1.00 36.97 ? 509 SER A N 1 ATOM 3882 C CA . SER A 1 509 ? -123.352 3.819 288.076 1.00 31.33 ? 509 SER A CA 1 ATOM 3883 C C . SER A 1 509 ? -122.524 4.820 287.282 1.00 28.85 ? 509 SER A C 1 ATOM 3884 O O . SER A 1 509 ? -123.046 5.845 286.830 1.00 29.65 ? 509 SER A O 1 ATOM 3885 C CB . SER A 1 509 ? -123.202 4.069 289.576 1.00 31.52 ? 509 SER A CB 1 ATOM 3886 O OG . SER A 1 509 ? -121.880 3.799 290.005 1.00 39.59 ? 509 SER A OG 1 ATOM 3887 N N . VAL A 1 510 ? -121.231 4.541 287.101 1.00 30.40 ? 510 VAL A N 1 ATOM 3888 C CA . VAL A 1 510 ? -120.381 5.444 286.332 1.00 30.35 ? 510 VAL A CA 1 ATOM 3889 C C . VAL A 1 510 ? -120.819 5.477 284.874 1.00 29.83 ? 510 VAL A C 1 ATOM 3890 O O . VAL A 1 510 ? -120.877 6.545 284.253 1.00 29.63 ? 510 VAL A O 1 ATOM 3891 C CB . VAL A 1 510 ? -118.903 5.038 286.473 1.00 32.60 ? 510 VAL A CB 1 ATOM 3892 C CG1 . VAL A 1 510 ? -118.038 5.828 285.504 1.00 29.75 ? 510 VAL A CG1 1 ATOM 3893 C CG2 . VAL A 1 510 ? -118.433 5.257 287.901 1.00 28.76 ? 510 VAL A CG2 1 ATOM 3894 N N . LEU A 1 511 ? -121.142 4.312 284.305 1.00 31.99 ? 511 LEU A N 1 ATOM 3895 C CA . LEU A 1 511 ? -121.609 4.273 282.923 1.00 37.97 ? 511 LEU A CA 1 ATOM 3896 C C . LEU A 1 511 ? -122.914 5.037 282.754 1.00 40.06 ? 511 LEU A C 1 ATOM 3897 O O . LEU A 1 511 ? -123.146 5.643 281.701 1.00 45.72 ? 511 LEU A O 1 ATOM 3898 C CB . LEU A 1 511 ? -121.771 2.825 282.462 1.00 35.61 ? 511 LEU A CB 1 ATOM 3899 C CG . LEU A 1 511 ? -120.478 2.132 282.029 1.00 40.19 ? 511 LEU A CG 1 ATOM 3900 C CD1 . LEU A 1 511 ? -120.676 0.628 281.929 1.00 39.90 ? 511 LEU A CD1 1 ATOM 3901 C CD2 . LEU A 1 511 ? -119.972 2.703 280.713 1.00 66.61 ? 511 LEU A CD2 1 ATOM 3902 N N . GLY A 1 512 ? -123.777 5.021 283.772 1.00 36.29 ? 512 GLY A N 1 ATOM 3903 C CA . GLY A 1 512 ? -124.956 5.867 283.737 1.00 41.87 ? 512 GLY A CA 1 ATOM 3904 C C . GLY A 1 512 ? -124.614 7.342 283.785 1.00 36.72 ? 512 GLY A C 1 ATOM 3905 O O . GLY A 1 512 ? -125.308 8.165 283.181 1.00 44.33 ? 512 GLY A O 1 ATOM 3906 N N . LYS A 1 513 ? -123.541 7.697 284.496 1.00 32.13 ? 513 LYS A N 1 ATOM 3907 C CA . LYS A 1 513 ? -123.084 9.080 284.524 1.00 33.12 ? 513 LYS A CA 1 ATOM 3908 C C . LYS A 1 513 ? -122.511 9.521 283.185 1.00 34.12 ? 513 LYS A C 1 ATOM 3909 O O . LYS A 1 513 ? -122.483 10.724 282.904 1.00 41.28 ? 513 LYS A O 1 ATOM 3910 C CB . LYS A 1 513 ? -122.032 9.267 285.619 1.00 29.38 ? 513 LYS A CB 1 ATOM 3911 C CG . LYS A 1 513 ? -122.542 9.023 287.027 1.00 23.19 ? 513 LYS A CG 1 ATOM 3912 C CD . LYS A 1 513 ? -121.501 9.405 288.065 1.00 22.12 ? 513 LYS A CD 1 ATOM 3913 C CE . LYS A 1 513 ? -122.068 9.319 289.473 1.00 22.01 ? 513 LYS A CE 1 ATOM 3914 N NZ . LYS A 1 513 ? -121.091 9.778 290.498 1.00 25.36 ? 513 LYS A NZ 1 ATOM 3915 N N . VAL A 1 514 ? -122.055 8.579 282.358 1.00 35.22 ? 514 VAL A N 1 ATOM 3916 C CA . VAL A 1 514 ? -121.458 8.938 281.075 1.00 36.48 ? 514 VAL A CA 1 ATOM 3917 C C . VAL A 1 514 ? -122.506 9.539 280.148 1.00 47.32 ? 514 VAL A C 1 ATOM 3918 O O . VAL A 1 514 ? -122.295 10.603 279.554 1.00 50.65 ? 514 VAL A O 1 ATOM 3919 C CB . VAL A 1 514 ? -120.778 7.713 280.438 1.00 35.14 ? 514 VAL A CB 1 ATOM 3920 C CG1 . VAL A 1 514 ? -120.253 8.061 279.055 1.00 40.40 ? 514 VAL A CG1 1 ATOM 3921 C CG2 . VAL A 1 514 ? -119.653 7.211 281.327 1.00 35.59 ? 514 VAL A CG2 1 ATOM 3922 N N . LYS A 1 515 ? -123.654 8.870 280.012 1.00 43.19 ? 515 LYS A N 1 ATOM 3923 C CA . LYS A 1 515 ? -124.692 9.374 279.119 1.00 44.78 ? 515 LYS A CA 1 ATOM 3924 C C . LYS A 1 515 ? -125.360 10.624 279.676 1.00 43.06 ? 515 LYS A C 1 ATOM 3925 O O . LYS A 1 515 ? -125.802 11.482 278.903 1.00 44.41 ? 515 LYS A O 1 ATOM 3926 C CB . LYS A 1 515 ? -125.726 8.284 278.844 1.00 66.83 ? 515 LYS A CB 1 ATOM 3927 C CG . LYS A 1 515 ? -125.115 6.927 278.543 1.00 77.89 ? 515 LYS A CG 1 ATOM 3928 C CD . LYS A 1 515 ? -126.013 6.107 277.635 1.00 72.70 ? 515 LYS A CD 1 ATOM 3929 C CE . LYS A 1 515 ? -126.059 4.653 278.065 1.00 69.13 ? 515 LYS A CE 1 ATOM 3930 N NZ . LYS A 1 515 ? -126.821 3.816 277.097 1.00 74.19 ? 515 LYS A NZ 1 ATOM 3931 N N . TYR A 1 516 ? -125.447 10.749 281.004 1.00 38.54 ? 516 TYR A N 1 ATOM 3932 C CA . TYR A 1 516 ? -125.899 12.010 281.583 1.00 35.88 ? 516 TYR A CA 1 ATOM 3933 C C . TYR A 1 516 ? -124.968 13.153 281.206 1.00 37.01 ? 516 TYR A C 1 ATOM 3934 O O . TYR A 1 516 ? -125.402 14.306 281.112 1.00 53.90 ? 516 TYR A O 1 ATOM 3935 C CB . TYR A 1 516 ? -126.007 11.896 283.104 1.00 35.87 ? 516 TYR A CB 1 ATOM 3936 C CG . TYR A 1 516 ? -126.676 13.092 283.741 1.00 34.54 ? 516 TYR A CG 1 ATOM 3937 C CD1 . TYR A 1 516 ? -128.059 13.204 283.775 1.00 45.43 ? 516 TYR A CD1 1 ATOM 3938 C CD2 . TYR A 1 516 ? -125.922 14.119 284.293 1.00 36.06 ? 516 TYR A CD2 1 ATOM 3939 C CE1 . TYR A 1 516 ? -128.673 14.301 284.349 1.00 36.12 ? 516 TYR A CE1 1 ATOM 3940 C CE2 . TYR A 1 516 ? -126.526 15.219 284.868 1.00 42.35 ? 516 TYR A CE2 1 ATOM 3941 C CZ . TYR A 1 516 ? -127.901 15.305 284.894 1.00 36.08 ? 516 TYR A CZ 1 ATOM 3942 O OH . TYR A 1 516 ? -128.503 16.401 285.466 1.00 34.89 ? 516 TYR A OH 1 ATOM 3943 N N . VAL A 1 517 ? -123.688 12.854 280.990 1.00 38.41 ? 517 VAL A N 1 ATOM 3944 C CA . VAL A 1 517 ? -122.760 13.863 280.498 1.00 35.58 ? 517 VAL A CA 1 ATOM 3945 C C . VAL A 1 517 ? -122.871 14.000 278.983 1.00 40.80 ? 517 VAL A C 1 ATOM 3946 O O . VAL A 1 517 ? -122.694 15.097 278.439 1.00 56.85 ? 517 VAL A O 1 ATOM 3947 C CB . VAL A 1 517 ? -121.327 13.508 280.937 1.00 34.81 ? 517 VAL A CB 1 ATOM 3948 C CG1 . VAL A 1 517 ? -120.294 14.310 280.156 1.00 46.79 ? 517 VAL A CG1 1 ATOM 3949 C CG2 . VAL A 1 517 ? -121.160 13.724 282.432 1.00 31.48 ? 517 VAL A CG2 1 ATOM 3950 N N . ASP A 1 518 ? -123.202 12.911 278.287 1.00 42.79 ? 518 ASP A N 1 ATOM 3951 C CA . ASP A 1 518 ? -123.136 12.862 276.831 1.00 44.87 ? 518 ASP A CA 1 ATOM 3952 C C . ASP A 1 518 ? -124.072 13.861 276.161 1.00 46.35 ? 518 ASP A C 1 ATOM 3953 O O . ASP A 1 518 ? -123.607 14.821 275.538 1.00 61.50 ? 518 ASP A O 1 ATOM 3954 C CB . ASP A 1 518 ? -123.435 11.445 276.339 1.00 47.48 ? 518 ASP A CB 1 ATOM 3955 C CG . ASP A 1 518 ? -122.245 10.517 276.484 1.00 45.34 ? 518 ASP A CG 1 ATOM 3956 O OD1 . ASP A 1 518 ? -121.126 11.021 276.728 1.00 43.62 ? 518 ASP A OD1 1 ATOM 3957 O OD2 . ASP A 1 518 ? -122.424 9.288 276.357 1.00 47.11 ? 518 ASP A OD2 1 ATOM 3958 N N . ARG A 1 519 ? -125.388 13.653 276.263 1.00 48.34 ? 519 ARG A N 1 ATOM 3959 C CA . ARG A 1 519 ? -126.332 14.516 275.559 1.00 52.46 ? 519 ARG A CA 1 ATOM 3960 C C . ARG A 1 519 ? -127.214 15.335 276.495 1.00 59.72 ? 519 ARG A C 1 ATOM 3961 O O . ARG A 1 519 ? -128.284 15.799 276.087 1.00 74.66 ? 519 ARG A O 1 ATOM 3962 C CB . ARG A 1 519 ? -127.173 13.708 274.571 1.00 68.32 ? 519 ARG A CB 1 ATOM 3963 C CG . ARG A 1 519 ? -126.308 13.021 273.533 1.00 68.59 ? 519 ARG A CG 1 ATOM 3964 C CD . ARG A 1 519 ? -126.625 13.520 272.135 1.00 95.14 ? 519 ARG A CD 1 ATOM 3965 N NE . ARG A 1 519 ? -125.404 13.813 271.393 1.00 92.99 ? 519 ARG A NE 1 ATOM 3966 C CZ . ARG A 1 519 ? -125.355 14.560 270.295 1.00 68.21 ? 519 ARG A CZ 1 ATOM 3967 N NH1 . ARG A 1 519 ? -126.461 15.102 269.808 1.00 68.28 ? 519 ARG A NH1 1 ATOM 3968 N NH2 . ARG A 1 519 ? -124.194 14.772 269.687 1.00 64.50 ? 519 ARG A NH2 1 ATOM 3969 N N . ASN A 1 520 ? -126.792 15.521 277.741 1.00 43.12 ? 520 ASN A N 1 ATOM 3970 C CA . ASN A 1 520 ? -127.015 16.793 278.412 1.00 37.97 ? 520 ASN A CA 1 ATOM 3971 C C . ASN A 1 520 ? -125.897 17.770 278.086 1.00 38.83 ? 520 ASN A C 1 ATOM 3972 O O . ASN A 1 520 ? -125.876 18.883 278.623 1.00 38.99 ? 520 ASN A O 1 ATOM 3973 C CB . ASN A 1 520 ? -127.132 16.606 279.928 1.00 33.46 ? 520 ASN A CB 1 ATOM 3974 C CG . ASN A 1 520 ? -128.336 15.774 280.324 1.00 35.80 ? 520 ASN A CG 1 ATOM 3975 O OD1 . ASN A 1 520 ? -128.225 14.573 280.567 1.00 39.76 ? 520 ASN A OD1 1 ATOM 3976 N ND2 . ASN A 1 520 ? -129.498 16.414 280.393 1.00 44.48 ? 520 ASN A ND2 1 ATOM 3977 N N . LYS A 1 521 ? -124.968 17.352 277.222 1.00 40.18 ? 521 LYS A N 1 ATOM 3978 C CA . LYS A 1 521 ? -123.874 18.180 276.718 1.00 37.11 ? 521 LYS A CA 1 ATOM 3979 C C . LYS A 1 521 ? -122.995 18.698 277.851 1.00 33.17 ? 521 LYS A C 1 ATOM 3980 O O . LYS A 1 521 ? -122.512 19.831 277.822 1.00 33.38 ? 521 LYS A O 1 ATOM 3981 C CB . LYS A 1 521 ? -124.400 19.328 275.854 1.00 38.03 ? 521 LYS A CB 1 ATOM 3982 C CG . LYS A 1 521 ? -125.047 18.870 274.547 1.00 41.00 ? 521 LYS A CG 1 ATOM 3983 C CD . LYS A 1 521 ? -124.322 17.681 273.912 1.00 43.31 ? 521 LYS A CD 1 ATOM 3984 C CE . LYS A 1 521 ? -122.959 18.061 273.345 1.00 51.52 ? 521 LYS A CE 1 ATOM 3985 N NZ . LYS A 1 521 ? -122.148 16.855 273.013 1.00 48.25 ? 521 LYS A NZ 1 ATOM 3986 N N . LEU A 1 522 ? -122.773 17.854 278.853 1.00 32.87 ? 522 LEU A N 1 ATOM 3987 C CA . LEU A 1 522 ? -121.871 18.208 279.933 1.00 31.76 ? 522 LEU A CA 1 ATOM 3988 C C . LEU A 1 522 ? -120.422 18.005 279.498 1.00 31.10 ? 522 LEU A C 1 ATOM 3989 O O . LEU A 1 522 ? -120.122 17.239 278.577 1.00 32.16 ? 522 LEU A O 1 ATOM 3990 C CB . LEU A 1 522 ? -122.186 17.392 281.186 1.00 33.53 ? 522 LEU A CB 1 ATOM 3991 C CG . LEU A 1 522 ? -123.580 17.669 281.758 1.00 31.17 ? 522 LEU A CG 1 ATOM 3992 C CD1 . LEU A 1 522 ? -123.811 16.902 283.046 1.00 28.11 ? 522 LEU A CD1 1 ATOM 3993 C CD2 . LEU A 1 522 ? -123.784 19.162 281.975 1.00 30.14 ? 522 LEU A CD2 1 ATOM 3994 N N . GLY A 1 523 ? -119.518 18.716 280.175 1.00 32.36 ? 523 GLY A N 1 ATOM 3995 C CA . GLY A 1 523 ? -118.134 18.754 279.730 1.00 30.97 ? 523 GLY A CA 1 ATOM 3996 C C . GLY A 1 523 ? -117.431 17.414 279.827 1.00 28.55 ? 523 GLY A C 1 ATOM 3997 O O . GLY A 1 523 ? -116.725 17.006 278.900 1.00 34.53 ? 523 GLY A O 1 ATOM 3998 N N . GLY A 1 524 ? -117.606 16.715 280.942 1.00 26.20 ? 524 GLY A N 1 ATOM 3999 C CA . GLY A 1 524 ? -116.935 15.436 281.116 1.00 27.39 ? 524 GLY A CA 1 ATOM 4000 C C . GLY A 1 524 ? -117.068 14.931 282.534 1.00 24.12 ? 524 GLY A C 1 ATOM 4001 O O . GLY A 1 524 ? -118.053 15.219 283.224 1.00 21.85 ? 524 GLY A O 1 ATOM 4002 N N . LEU A 1 525 ? -116.061 14.174 282.961 1.00 20.93 ? 525 LEU A N 1 ATOM 4003 C CA . LEU A 1 525 ? -116.060 13.549 284.274 1.00 19.39 ? 525 LEU A CA 1 ATOM 4004 C C . LEU A 1 525 ? -114.701 13.727 284.934 1.00 21.62 ? 525 LEU A C 1 ATOM 4005 O O . LEU A 1 525 ? -113.664 13.705 284.264 1.00 23.53 ? 525 LEU A O 1 ATOM 4006 C CB . LEU A 1 525 ? -116.398 12.052 284.188 1.00 21.46 ? 525 LEU A CB 1 ATOM 4007 C CG . LEU A 1 525 ? -117.732 11.636 283.561 1.00 25.36 ? 525 LEU A CG 1 ATOM 4008 C CD1 . LEU A 1 525 ? -117.610 11.496 282.049 1.00 26.68 ? 525 LEU A CD1 1 ATOM 4009 C CD2 . LEU A 1 525 ? -118.236 10.343 284.178 1.00 29.21 ? 525 LEU A CD2 1 ATOM 4010 N N . PHE A 1 526 ? -114.720 13.913 286.252 1.00 22.31 ? 526 PHE A N 1 ATOM 4011 C CA . PHE A 1 526 ? -113.519 13.917 287.072 1.00 21.15 ? 526 PHE A CA 1 ATOM 4012 C C . PHE A 1 526 ? -113.765 13.040 288.292 1.00 22.01 ? 526 PHE A C 1 ATOM 4013 O O . PHE A 1 526 ? -114.909 12.795 288.682 1.00 21.71 ? 526 PHE A O 1 ATOM 4014 C CB . PHE A 1 526 ? -113.117 15.340 287.494 1.00 21.62 ? 526 PHE A CB 1 ATOM 4015 C CG . PHE A 1 526 ? -113.861 15.858 288.692 1.00 22.94 ? 526 PHE A CG 1 ATOM 4016 C CD1 . PHE A 1 526 ? -115.137 16.378 288.561 1.00 20.17 ? 526 PHE A CD1 1 ATOM 4017 C CD2 . PHE A 1 526 ? -113.279 15.835 289.950 1.00 23.60 ? 526 PHE A CD2 1 ATOM 4018 C CE1 . PHE A 1 526 ? -115.819 16.861 289.660 1.00 21.13 ? 526 PHE A CE1 1 ATOM 4019 C CE2 . PHE A 1 526 ? -113.959 16.313 291.054 1.00 19.99 ? 526 PHE A CE2 1 ATOM 4020 C CZ . PHE A 1 526 ? -115.231 16.826 290.908 1.00 22.00 ? 526 PHE A CZ 1 ATOM 4021 N N . ALA A 1 527 ? -112.678 12.561 288.895 1.00 22.16 ? 527 ALA A N 1 ATOM 4022 C CA . ALA A 1 527 ? -112.790 11.552 289.936 1.00 23.69 ? 527 ALA A CA 1 ATOM 4023 C C . ALA A 1 527 ? -111.833 11.836 291.084 1.00 20.88 ? 527 ALA A C 1 ATOM 4024 O O . ALA A 1 527 ? -110.788 12.468 290.908 1.00 24.01 ? 527 ALA A O 1 ATOM 4025 C CB . ALA A 1 527 ? -112.522 10.148 289.381 1.00 25.15 ? 527 ALA A CB 1 ATOM 4026 N N . TRP A 1 528 ? -112.215 11.356 292.264 1.00 19.37 ? 528 TRP A N 1 ATOM 4027 C CA . TRP A 1 528 ? -111.369 11.363 293.452 1.00 19.69 ? 528 TRP A CA 1 ATOM 4028 C C . TRP A 1 528 ? -111.505 10.011 294.143 1.00 22.48 ? 528 TRP A C 1 ATOM 4029 O O . TRP A 1 528 ? -112.618 9.592 294.455 1.00 35.79 ? 528 TRP A O 1 ATOM 4030 C CB . TRP A 1 528 ? -111.764 12.493 294.410 1.00 19.22 ? 528 TRP A CB 1 ATOM 4031 C CG . TRP A 1 528 ? -111.051 12.450 295.742 1.00 22.71 ? 528 TRP A CG 1 ATOM 4032 C CD1 . TRP A 1 528 ? -111.286 11.584 296.773 1.00 22.27 ? 528 TRP A CD1 1 ATOM 4033 C CD2 . TRP A 1 528 ? -110.009 13.326 296.190 1.00 26.69 ? 528 TRP A CD2 1 ATOM 4034 N NE1 . TRP A 1 528 ? -110.444 11.855 297.823 1.00 26.43 ? 528 TRP A NE1 1 ATOM 4035 C CE2 . TRP A 1 528 ? -109.653 12.923 297.491 1.00 28.71 ? 528 TRP A CE2 1 ATOM 4036 C CE3 . TRP A 1 528 ? -109.342 14.411 295.616 1.00 22.22 ? 528 TRP A CE3 1 ATOM 4037 C CZ2 . TRP A 1 528 ? -108.655 13.563 298.224 1.00 28.41 ? 528 TRP A CZ2 1 ATOM 4038 C CZ3 . TRP A 1 528 ? -108.352 15.044 296.343 1.00 20.23 ? 528 TRP A CZ3 1 ATOM 4039 C CH2 . TRP A 1 528 ? -108.020 14.620 297.634 1.00 23.73 ? 528 TRP A CH2 1 ATOM 4040 N N . GLU A 1 529 ? -110.393 9.321 294.378 1.00 19.08 ? 529 GLU A N 1 ATOM 4041 C CA . GLU A 1 529 ? -109.073 9.751 293.937 1.00 17.09 ? 529 GLU A CA 1 ATOM 4042 C C . GLU A 1 529 ? -108.479 8.674 293.034 1.00 16.22 ? 529 GLU A C 1 ATOM 4043 O O . GLU A 1 529 ? -108.879 7.512 293.104 1.00 19.28 ? 529 GLU A O 1 ATOM 4044 C CB . GLU A 1 529 ? -108.167 10.030 295.139 1.00 18.71 ? 529 GLU A CB 1 ATOM 4045 C CG . GLU A 1 529 ? -108.238 8.969 296.225 1.00 19.26 ? 529 GLU A CG 1 ATOM 4046 C CD . GLU A 1 529 ? -107.596 9.416 297.525 1.00 35.04 ? 529 GLU A CD 1 ATOM 4047 O OE1 . GLU A 1 529 ? -106.620 8.774 297.965 1.00 41.41 ? 529 GLU A OE1 1 ATOM 4048 O OE2 . GLU A 1 529 ? -108.070 10.411 298.111 1.00 30.93 ? 529 GLU A OE2 1 ATOM 4049 N N . ILE A 1 530 ? -107.522 9.064 292.188 1.00 13.81 ? 530 ILE A N 1 ATOM 4050 C CA . ILE A 1 530 ? -107.052 8.182 291.124 1.00 13.83 ? 530 ILE A CA 1 ATOM 4051 C C . ILE A 1 530 ? -106.353 6.942 291.666 1.00 15.82 ? 530 ILE A C 1 ATOM 4052 O O . ILE A 1 530 ? -106.299 5.915 290.982 1.00 24.10 ? 530 ILE A O 1 ATOM 4053 C CB . ILE A 1 530 ? -106.130 8.963 290.161 1.00 13.94 ? 530 ILE A CB 1 ATOM 4054 C CG1 . ILE A 1 530 ? -105.933 8.187 288.858 1.00 17.84 ? 530 ILE A CG1 1 ATOM 4055 C CG2 . ILE A 1 530 ? -104.790 9.259 290.816 1.00 14.88 ? 530 ILE A CG2 1 ATOM 4056 C CD1 . ILE A 1 530 ? -107.226 7.775 288.195 1.00 12.87 ? 530 ILE A CD1 1 ATOM 4057 N N . ASP A 1 531 ? -105.823 7.002 292.888 1.00 15.81 ? 531 ASP A N 1 ATOM 4058 C CA . ASP A 1 531 ? -105.102 5.862 293.440 1.00 14.14 ? 531 ASP A CA 1 ATOM 4059 C C . ASP A 1 531 ? -106.026 4.753 293.921 1.00 17.08 ? 531 ASP A C 1 ATOM 4060 O O . ASP A 1 531 ? -105.581 3.607 294.050 1.00 17.42 ? 531 ASP A O 1 ATOM 4061 C CB . ASP A 1 531 ? -104.208 6.315 294.593 1.00 15.50 ? 531 ASP A CB 1 ATOM 4062 C CG . ASP A 1 531 ? -104.994 6.948 295.717 1.00 20.61 ? 531 ASP A CG 1 ATOM 4063 O OD1 . ASP A 1 531 ? -105.471 6.206 296.601 1.00 20.50 ? 531 ASP A OD1 1 ATOM 4064 O OD2 . ASP A 1 531 ? -105.139 8.187 295.712 1.00 20.64 ? 531 ASP A OD2 1 ATOM 4065 N N . ALA A 1 532 ? -107.294 5.060 294.191 1.00 18.28 ? 532 ALA A N 1 ATOM 4066 C CA . ALA A 1 532 ? -108.215 4.063 294.719 1.00 19.54 ? 532 ALA A CA 1 ATOM 4067 C C . ALA A 1 532 ? -108.875 3.223 293.635 1.00 15.81 ? 532 ALA A C 1 ATOM 4068 O O . ALA A 1 532 ? -109.559 2.249 293.963 1.00 18.27 ? 532 ALA A O 1 ATOM 4069 C CB . ALA A 1 532 ? -109.290 4.740 295.569 1.00 16.26 ? 532 ALA A CB 1 ATOM 4070 N N . ASP A 1 533 ? -108.688 3.567 292.365 1.00 14.78 ? 533 ASP A N 1 ATOM 4071 C CA . ASP A 1 533 ? -109.272 2.814 291.266 1.00 19.62 ? 533 ASP A CA 1 ATOM 4072 C C . ASP A 1 533 ? -108.352 1.669 290.863 1.00 27.35 ? 533 ASP A C 1 ATOM 4073 O O . ASP A 1 533 ? -107.125 1.797 290.907 1.00 51.41 ? 533 ASP A O 1 ATOM 4074 C CB . ASP A 1 533 ? -109.528 3.726 290.065 1.00 18.90 ? 533 ASP A CB 1 ATOM 4075 C CG . ASP A 1 533 ? -110.202 3.004 288.915 1.00 19.34 ? 533 ASP A CG 1 ATOM 4076 O OD1 . ASP A 1 533 ? -110.925 2.020 289.171 1.00 19.90 ? 533 ASP A OD1 1 ATOM 4077 O OD2 . ASP A 1 533 ? -110.005 3.421 287.754 1.00 25.96 ? 533 ASP A OD2 1 ATOM 4078 N N . ASN A 1 534 ? -108.955 0.546 290.472 1.00 22.36 ? 534 ASN A N 1 ATOM 4079 C CA . ASN A 1 534 ? -108.214 -0.609 289.982 1.00 20.48 ? 534 ASN A CA 1 ATOM 4080 C C . ASN A 1 534 ? -108.338 -0.768 288.470 1.00 22.67 ? 534 ASN A C 1 ATOM 4081 O O . ASN A 1 534 ? -108.060 -1.847 287.937 1.00 22.03 ? 534 ASN A O 1 ATOM 4082 C CB . ASN A 1 534 ? -108.673 -1.881 290.698 1.00 20.02 ? 534 ASN A CB 1 ATOM 4083 C CG . ASN A 1 534 ? -110.053 -2.334 290.263 1.00 25.09 ? 534 ASN A CG 1 ATOM 4084 O OD1 . ASN A 1 534 ? -110.864 -1.537 289.794 1.00 30.17 ? 534 ASN A OD1 1 ATOM 4085 N ND2 . ASN A 1 534 ? -110.326 -3.624 290.419 1.00 21.05 ? 534 ASN A ND2 1 ATOM 4086 N N . GLY A 1 535 ? -108.753 0.287 287.770 1.00 24.22 ? 535 GLY A N 1 ATOM 4087 C CA . GLY A 1 535 ? -108.905 0.266 286.335 1.00 22.32 ? 535 GLY A CA 1 ATOM 4088 C C . GLY A 1 535 ? -110.338 0.186 285.851 1.00 22.01 ? 535 GLY A C 1 ATOM 4089 O O . GLY A 1 535 ? -110.617 0.589 284.717 1.00 23.56 ? 535 GLY A O 1 ATOM 4090 N N . ASP A 1 536 ? -111.254 -0.316 286.682 1.00 21.97 ? 536 ASP A N 1 ATOM 4091 C CA . ASP A 1 536 ? -112.639 -0.472 286.249 1.00 24.12 ? 536 ASP A CA 1 ATOM 4092 C C . ASP A 1 536 ? -113.305 0.880 286.028 1.00 26.86 ? 536 ASP A C 1 ATOM 4093 O O . ASP A 1 536 ? -113.940 1.109 284.992 1.00 51.21 ? 536 ASP A O 1 ATOM 4094 C CB . ASP A 1 536 ? -113.421 -1.287 287.279 1.00 25.32 ? 536 ASP A CB 1 ATOM 4095 C CG . ASP A 1 536 ? -112.857 -2.677 287.475 1.00 29.95 ? 536 ASP A CG 1 ATOM 4096 O OD1 . ASP A 1 536 ? -112.279 -3.227 286.516 1.00 47.75 ? 536 ASP A OD1 1 ATOM 4097 O OD2 . ASP A 1 536 ? -112.988 -3.218 288.593 1.00 32.08 ? 536 ASP A OD2 1 ATOM 4098 N N . LEU A 1 537 ? -113.166 1.791 286.993 1.00 25.25 ? 537 LEU A N 1 ATOM 4099 C CA . LEU A 1 537 ? -113.924 3.037 286.951 1.00 23.32 ? 537 LEU A CA 1 ATOM 4100 C C . LEU A 1 537 ? -113.431 3.959 285.842 1.00 27.75 ? 537 LEU A C 1 ATOM 4101 O O . LEU A 1 537 ? -114.239 4.572 285.136 1.00 33.96 ? 537 LEU A O 1 ATOM 4102 C CB . LEU A 1 537 ? -113.848 3.736 288.308 1.00 21.33 ? 537 LEU A CB 1 ATOM 4103 C CG . LEU A 1 537 ? -114.355 2.906 289.489 1.00 21.60 ? 537 LEU A CG 1 ATOM 4104 C CD1 . LEU A 1 537 ? -114.355 3.725 290.766 1.00 23.80 ? 537 LEU A CD1 1 ATOM 4105 C CD2 . LEU A 1 537 ? -115.743 2.358 289.202 1.00 35.58 ? 537 LEU A CD2 1 ATOM 4106 N N . LEU A 1 538 ? -112.112 4.070 285.671 1.00 23.95 ? 538 LEU A N 1 ATOM 4107 C CA . LEU A 1 538 ? -111.579 4.974 284.657 1.00 24.13 ? 538 LEU A CA 1 ATOM 4108 C C . LEU A 1 538 ? -111.903 4.484 283.251 1.00 27.75 ? 538 LEU A C 1 ATOM 4109 O O . LEU A 1 538 ? -112.140 5.293 282.346 1.00 27.76 ? 538 LEU A O 1 ATOM 4110 C CB . LEU A 1 538 ? -110.072 5.137 284.839 1.00 23.24 ? 538 LEU A CB 1 ATOM 4111 C CG . LEU A 1 538 ? -109.391 6.102 283.868 1.00 24.67 ? 538 LEU A CG 1 ATOM 4112 C CD1 . LEU A 1 538 ? -110.033 7.476 283.947 1.00 23.60 ? 538 LEU A CD1 1 ATOM 4113 C CD2 . LEU A 1 538 ? -107.908 6.188 284.165 1.00 30.85 ? 538 LEU A CD2 1 ATOM 4114 N N . ASN A 1 539 ? -111.916 3.165 283.047 1.00 28.79 ? 539 ASN A N 1 ATOM 4115 C CA . ASN A 1 539 ? -112.294 2.623 281.745 1.00 29.78 ? 539 ASN A CA 1 ATOM 4116 C C . ASN A 1 539 ? -113.752 2.924 281.426 1.00 39.82 ? 539 ASN A C 1 ATOM 4117 O O . ASN A 1 539 ? -114.097 3.197 280.270 1.00 56.55 ? 539 ASN A O 1 ATOM 4118 C CB . ASN A 1 539 ? -112.040 1.117 281.710 1.00 31.00 ? 539 ASN A CB 1 ATOM 4119 C CG . ASN A 1 539 ? -110.566 0.776 281.746 1.00 32.54 ? 539 ASN A CG 1 ATOM 4120 O OD1 . ASN A 1 539 ? -109.713 1.659 281.824 1.00 29.69 ? 539 ASN A OD1 1 ATOM 4121 N ND2 . ASN A 1 539 ? -110.259 -0.514 281.708 1.00 36.96 ? 539 ASN A ND2 1 ATOM 4122 N N . ALA A 1 540 ? -114.623 2.878 282.436 1.00 29.94 ? 540 ALA A N 1 ATOM 4123 C CA . ALA A 1 540 ? -116.027 3.202 282.216 1.00 32.51 ? 540 ALA A CA 1 ATOM 4124 C C . ALA A 1 540 ? -116.216 4.673 281.872 1.00 37.00 ? 540 ALA A C 1 ATOM 4125 O O . ALA A 1 540 ? -117.135 5.019 281.120 1.00 52.53 ? 540 ALA A O 1 ATOM 4126 C CB . ALA A 1 540 ? -116.851 2.835 283.450 1.00 34.44 ? 540 ALA A CB 1 ATOM 4127 N N . ILE A 1 541 ? -115.363 5.549 282.406 1.00 36.62 ? 541 ILE A N 1 ATOM 4128 C CA . ILE A 1 541 ? -115.462 6.971 282.092 1.00 34.96 ? 541 ILE A CA 1 ATOM 4129 C C . ILE A 1 541 ? -115.122 7.219 280.628 1.00 33.86 ? 541 ILE A C 1 ATOM 4130 O O . ILE A 1 541 ? -115.759 8.041 279.958 1.00 37.37 ? 541 ILE A O 1 ATOM 4131 C CB . ILE A 1 541 ? -114.556 7.786 283.033 1.00 28.91 ? 541 ILE A CB 1 ATOM 4132 C CG1 . ILE A 1 541 ? -115.011 7.627 284.484 1.00 26.16 ? 541 ILE A CG1 1 ATOM 4133 C CG2 . ILE A 1 541 ? -114.550 9.253 282.637 1.00 26.23 ? 541 ILE A CG2 1 ATOM 4134 C CD1 . ILE A 1 541 ? -114.148 8.369 285.479 1.00 26.66 ? 541 ILE A CD1 1 ATOM 4135 N N . ASN A 1 542 ? -114.126 6.506 280.105 1.00 33.96 ? 542 ASN A N 1 ATOM 4136 C CA . ASN A 1 542 ? -113.654 6.694 278.741 1.00 40.12 ? 542 ASN A CA 1 ATOM 4137 C C . ASN A 1 542 ? -114.381 5.805 277.736 1.00 44.94 ? 542 ASN A C 1 ATOM 4138 O O . ASN A 1 542 ? -113.864 5.580 276.636 1.00 46.44 ? 542 ASN A O 1 ATOM 4139 C CB . ASN A 1 542 ? -112.148 6.436 278.669 1.00 39.11 ? 542 ASN A CB 1 ATOM 4140 C CG . ASN A 1 542 ? -111.346 7.442 279.472 1.00 37.76 ? 542 ASN A CG 1 ATOM 4141 O OD1 . ASN A 1 542 ? -110.977 8.503 278.969 1.00 36.13 ? 542 ASN A OD1 1 ATOM 4142 N ND2 . ASN A 1 542 ? -111.072 7.112 280.728 1.00 39.23 ? 542 ASN A ND2 1 ATOM 4143 N N . ALA A 1 543 ? -115.562 5.302 278.085 1.00 48.27 ? 543 ALA A N 1 ATOM 4144 C CA . ALA A 1 543 ? -116.275 4.383 277.208 1.00 54.35 ? 543 ALA A CA 1 ATOM 4145 C C . ALA A 1 543 ? -116.850 5.124 276.008 1.00 61.99 ? 543 ALA A C 1 ATOM 4146 O O . ALA A 1 543 ? -117.581 6.108 276.161 1.00 64.36 ? 543 ALA A O 1 ATOM 4147 C CB . ALA A 1 543 ? -117.390 3.676 277.977 1.00 58.62 ? 543 ALA A CB 1 ATOM 4148 N N . GLN A 1 544 ? -116.518 4.648 274.810 1.00 77.79 ? 544 GLN A N 1 ATOM 4149 C CA . GLN A 1 544 ? -117.043 5.210 273.572 1.00 73.40 ? 544 GLN A CA 1 ATOM 4150 C C . GLN A 1 544 ? -118.335 4.490 273.205 1.00 84.74 ? 544 GLN A C 1 ATOM 4151 O O . GLN A 1 544 ? -118.325 3.283 272.940 1.00 91.64 ? 544 GLN A O 1 ATOM 4152 C CB . GLN A 1 544 ? -116.023 5.083 272.441 1.00 72.05 ? 544 GLN A CB 1 ATOM 4153 C CG . GLN A 1 544 ? -114.579 5.268 272.871 1.00 82.06 ? 544 GLN A CG 1 ATOM 4154 C CD . GLN A 1 544 ? -113.612 5.162 271.708 1.00 72.27 ? 544 GLN A CD 1 ATOM 4155 O OE1 . GLN A 1 544 ? -113.687 5.934 270.753 1.00 67.24 ? 544 GLN A OE1 1 ATOM 4156 N NE2 . GLN A 1 544 ? -112.697 4.203 271.783 1.00 67.23 ? 544 GLN A NE2 1 ATOM 4157 N N . PHE A 1 545 ? -119.441 5.227 273.188 1.00 89.42 ? 545 PHE A N 1 ATOM 4158 C CA . PHE A 1 545 ? -120.737 4.653 272.841 1.00 86.95 ? 545 PHE A CA 1 ATOM 4159 C C . PHE A 1 545 ? -121.265 5.233 271.533 1.00 78.85 ? 545 PHE A C 1 ATOM 4160 O O . PHE A 1 545 ? -122.353 4.877 271.080 1.00 68.82 ? 545 PHE A O 1 ATOM 4161 C CB . PHE A 1 545 ? -121.750 4.888 273.965 1.00 82.66 ? 545 PHE A CB 1 ATOM 4162 C CG . PHE A 1 545 ? -121.545 4.004 275.165 1.00 82.75 ? 545 PHE A CG 1 ATOM 4163 C CD1 . PHE A 1 545 ? -120.569 3.020 275.165 1.00 104.56 ? 545 PHE A CD1 1 ATOM 4164 C CD2 . PHE A 1 545 ? -122.331 4.159 276.295 1.00 75.41 ? 545 PHE A CD2 1 ATOM 4165 C CE1 . PHE A 1 545 ? -120.380 2.209 276.267 1.00 113.40 ? 545 PHE A CE1 1 ATOM 4166 C CE2 . PHE A 1 545 ? -122.148 3.351 277.401 1.00 83.45 ? 545 PHE A CE2 1 ATOM 4167 C CZ . PHE A 1 545 ? -121.171 2.374 277.386 1.00 123.98 ? 545 PHE A CZ 1 ATOM 4168 N N . ILE B 1 18 ? -115.487 24.424 260.968 1.00 43.94 ? 18 ILE B N 1 ATOM 4169 C CA . ILE B 1 18 ? -114.298 23.617 261.211 1.00 43.16 ? 18 ILE B CA 1 ATOM 4170 C C . ILE B 1 18 ? -114.662 22.136 261.212 1.00 42.17 ? 18 ILE B C 1 ATOM 4171 O O . ILE B 1 18 ? -115.791 21.770 261.544 1.00 47.65 ? 18 ILE B O 1 ATOM 4172 C CB . ILE B 1 18 ? -113.614 24.020 262.533 1.00 47.32 ? 18 ILE B CB 1 ATOM 4173 C CG1 . ILE B 1 18 ? -114.485 23.638 263.732 1.00 42.07 ? 18 ILE B CG1 1 ATOM 4174 C CG2 . ILE B 1 18 ? -113.317 25.511 262.544 1.00 56.36 ? 18 ILE B CG2 1 ATOM 4175 C CD1 . ILE B 1 18 ? -113.757 23.693 265.056 1.00 42.60 ? 18 ILE B CD1 1 ATOM 4176 N N . PRO B 1 19 ? -113.717 21.283 260.825 1.00 40.69 ? 19 PRO B N 1 ATOM 4177 C CA . PRO B 1 19 ? -113.963 19.838 260.869 1.00 44.92 ? 19 PRO B CA 1 ATOM 4178 C C . PRO B 1 19 ? -114.112 19.352 262.302 1.00 37.46 ? 19 PRO B C 1 ATOM 4179 O O . PRO B 1 19 ? -113.781 20.042 263.269 1.00 36.34 ? 19 PRO B O 1 ATOM 4180 C CB . PRO B 1 19 ? -112.720 19.238 260.203 1.00 39.65 ? 19 PRO B CB 1 ATOM 4181 C CG . PRO B 1 19 ? -112.125 20.359 259.415 1.00 37.24 ? 19 PRO B CG 1 ATOM 4182 C CD . PRO B 1 19 ? -112.423 21.599 260.198 1.00 38.23 ? 19 PRO B CD 1 ATOM 4183 N N . GLY B 1 20 ? -114.626 18.132 262.428 1.00 40.40 ? 20 GLY B N 1 ATOM 4184 C CA . GLY B 1 20 ? -114.762 17.526 263.736 1.00 48.27 ? 20 GLY B CA 1 ATOM 4185 C C . GLY B 1 20 ? -113.419 17.302 264.403 1.00 41.20 ? 20 GLY B C 1 ATOM 4186 O O . GLY B 1 20 ? -112.364 17.305 263.767 1.00 43.42 ? 20 GLY B O 1 ATOM 4187 N N . THR B 1 21 ? -113.467 17.113 265.714 1.00 42.96 ? 21 THR B N 1 ATOM 4188 C CA . THR B 1 21 ? -112.243 16.894 266.472 1.00 42.82 ? 21 THR B CA 1 ATOM 4189 C C . THR B 1 21 ? -111.620 15.560 266.076 1.00 44.70 ? 21 THR B C 1 ATOM 4190 O O . THR B 1 21 ? -112.313 14.535 266.063 1.00 63.35 ? 21 THR B O 1 ATOM 4191 C CB . THR B 1 21 ? -112.523 16.931 267.975 1.00 54.67 ? 21 THR B CB 1 ATOM 4192 O OG1 . THR B 1 21 ? -111.405 16.386 268.687 1.00 61.98 ? 21 THR B OG1 1 ATOM 4193 C CG2 . THR B 1 21 ? -113.782 16.141 268.314 1.00 59.73 ? 21 THR B CG2 1 ATOM 4194 N N . PRO B 1 22 ? -110.332 15.528 265.736 1.00 39.32 ? 22 PRO B N 1 ATOM 4195 C CA . PRO B 1 22 ? -109.701 14.270 265.326 1.00 38.12 ? 22 PRO B CA 1 ATOM 4196 C C . PRO B 1 22 ? -109.156 13.482 266.507 1.00 37.12 ? 22 PRO B C 1 ATOM 4197 O O . PRO B 1 22 ? -108.598 14.030 267.459 1.00 41.22 ? 22 PRO B O 1 ATOM 4198 C CB . PRO B 1 22 ? -108.568 14.740 264.401 1.00 36.65 ? 22 PRO B CB 1 ATOM 4199 C CG . PRO B 1 22 ? -108.344 16.210 264.735 1.00 35.84 ? 22 PRO B CG 1 ATOM 4200 C CD . PRO B 1 22 ? -109.377 16.647 265.735 1.00 36.58 ? 22 PRO B CD 1 ATOM 4201 N N . VAL B 1 23 ? -109.332 12.165 266.435 1.00 34.51 ? 23 VAL B N 1 ATOM 4202 C CA . VAL B 1 23 ? -108.924 11.248 267.492 1.00 33.95 ? 23 VAL B CA 1 ATOM 4203 C C . VAL B 1 23 ? -107.965 10.238 266.882 1.00 36.46 ? 23 VAL B C 1 ATOM 4204 O O . VAL B 1 23 ? -108.383 9.354 266.123 1.00 35.33 ? 23 VAL B O 1 ATOM 4205 C CB . VAL B 1 23 ? -110.124 10.547 268.140 1.00 36.14 ? 23 VAL B CB 1 ATOM 4206 C CG1 . VAL B 1 23 ? -109.651 9.504 269.140 1.00 38.16 ? 23 VAL B CG1 1 ATOM 4207 C CG2 . VAL B 1 23 ? -111.024 11.568 268.810 1.00 40.08 ? 23 VAL B CG2 1 ATOM 4208 N N . ILE B 1 24 ? -106.681 10.365 267.215 1.00 51.99 ? 24 ILE B N 1 ATOM 4209 C CA . ILE B 1 24 ? -105.673 9.456 266.689 1.00 35.74 ? 24 ILE B CA 1 ATOM 4210 C C . ILE B 1 24 ? -105.839 8.089 267.339 1.00 34.32 ? 24 ILE B C 1 ATOM 4211 O O . ILE B 1 24 ? -105.870 7.969 268.570 1.00 35.71 ? 24 ILE B O 1 ATOM 4212 C CB . ILE B 1 24 ? -104.266 10.021 266.928 1.00 32.23 ? 24 ILE B CB 1 ATOM 4213 C CG1 . ILE B 1 24 ? -104.147 11.421 266.327 1.00 35.48 ? 24 ILE B CG1 1 ATOM 4214 C CG2 . ILE B 1 24 ? -103.224 9.110 266.319 1.00 33.08 ? 24 ILE B CG2 1 ATOM 4215 C CD1 . ILE B 1 24 ? -102.797 12.066 266.549 1.00 48.03 ? 24 ILE B CD1 1 ATOM 4216 N N . ASP B 1 25 ? -105.948 7.053 266.512 1.00 35.88 ? 25 ASP B N 1 ATOM 4217 C CA . ASP B 1 25 ? -106.156 5.704 267.018 1.00 37.22 ? 25 ASP B CA 1 ATOM 4218 C C . ASP B 1 25 ? -104.938 5.226 267.801 1.00 37.75 ? 25 ASP B C 1 ATOM 4219 O O . ASP B 1 25 ? -103.799 5.609 267.521 1.00 55.11 ? 25 ASP B O 1 ATOM 4220 C CB . ASP B 1 25 ? -106.442 4.741 265.867 1.00 37.13 ? 25 ASP B CB 1 ATOM 4221 C CG . ASP B 1 25 ? -107.478 5.280 264.901 1.00 43.97 ? 25 ASP B CG 1 ATOM 4222 O OD1 . ASP B 1 25 ? -108.328 6.089 265.328 1.00 51.12 ? 25 ASP B OD1 1 ATOM 4223 O OD2 . ASP B 1 25 ? -107.440 4.895 263.713 1.00 40.67 ? 25 ASP B OD2 1 ATOM 4224 N N . TRP B 1 26 ? -105.190 4.377 268.794 1.00 35.17 ? 26 TRP B N 1 ATOM 4225 C CA . TRP B 1 26 ? -104.105 3.827 269.593 1.00 37.65 ? 26 TRP B CA 1 ATOM 4226 C C . TRP B 1 26 ? -103.318 2.800 268.789 1.00 38.59 ? 26 TRP B C 1 ATOM 4227 O O . TRP B 1 26 ? -103.887 2.015 268.026 1.00 40.38 ? 26 TRP B O 1 ATOM 4228 C CB . TRP B 1 26 ? -104.647 3.184 270.868 1.00 51.34 ? 26 TRP B CB 1 ATOM 4229 C CG . TRP B 1 26 ? -103.568 2.640 271.760 1.00 63.09 ? 26 TRP B CG 1 ATOM 4230 C CD1 . TRP B 1 26 ? -102.920 3.302 272.762 1.00 47.69 ? 26 TRP B CD1 1 ATOM 4231 C CD2 . TRP B 1 26 ? -103.006 1.322 271.722 1.00 43.09 ? 26 TRP B CD2 1 ATOM 4232 N NE1 . TRP B 1 26 ? -101.994 2.478 273.353 1.00 39.70 ? 26 TRP B NE1 1 ATOM 4233 C CE2 . TRP B 1 26 ? -102.026 1.257 272.732 1.00 40.40 ? 26 TRP B CE2 1 ATOM 4234 C CE3 . TRP B 1 26 ? -103.237 0.191 270.933 1.00 43.34 ? 26 TRP B CE3 1 ATOM 4235 C CZ2 . TRP B 1 26 ? -101.279 0.106 272.974 1.00 57.94 ? 26 TRP B CZ2 1 ATOM 4236 C CZ3 . TRP B 1 26 ? -102.494 -0.951 271.175 1.00 55.70 ? 26 TRP B CZ3 1 ATOM 4237 C CH2 . TRP B 1 26 ? -101.527 -0.985 272.187 1.00 49.50 ? 26 TRP B CH2 1 ATOM 4238 N N . ALA B 1 27 ? -102.002 2.809 268.971 1.00 38.73 ? 27 ALA B N 1 ATOM 4239 C CA . ALA B 1 27 ? -101.111 1.870 268.302 1.00 38.25 ? 27 ALA B CA 1 ATOM 4240 C C . ALA B 1 27 ? -99.753 1.941 268.984 1.00 38.78 ? 27 ALA B C 1 ATOM 4241 O O . ALA B 1 27 ? -99.467 2.867 269.747 1.00 36.34 ? 27 ALA B O 1 ATOM 4242 C CB . ALA B 1 27 ? -100.986 2.170 266.806 1.00 37.80 ? 27 ALA B CB 1 ATOM 4243 N N . ASP B 1 28 ? -98.920 0.943 268.703 1.00 48.37 ? 28 ASP B N 1 ATOM 4244 C CA . ASP B 1 28 ? -97.549 0.940 269.193 1.00 35.79 ? 28 ASP B CA 1 ATOM 4245 C C . ASP B 1 28 ? -96.717 1.883 268.333 1.00 32.03 ? 28 ASP B C 1 ATOM 4246 O O . ASP B 1 28 ? -96.602 1.685 267.119 1.00 29.52 ? 28 ASP B O 1 ATOM 4247 C CB . ASP B 1 28 ? -96.971 -0.473 269.164 1.00 38.13 ? 28 ASP B CB 1 ATOM 4248 C CG . ASP B 1 28 ? -95.500 -0.509 269.531 1.00 40.66 ? 28 ASP B CG 1 ATOM 4249 O OD1 . ASP B 1 28 ? -95.063 0.348 270.328 1.00 39.78 ? 28 ASP B OD1 1 ATOM 4250 O OD2 . ASP B 1 28 ? -94.779 -1.390 269.019 1.00 49.83 ? 28 ASP B OD2 1 ATOM 4251 N N . ARG B 1 29 ? -96.144 2.909 268.958 1.00 32.20 ? 29 ARG B N 1 ATOM 4252 C CA . ARG B 1 29 ? -95.383 3.927 268.245 1.00 31.26 ? 29 ARG B CA 1 ATOM 4253 C C . ARG B 1 29 ? -93.911 3.910 268.643 1.00 31.67 ? 29 ARG B C 1 ATOM 4254 O O . ARG B 1 29 ? -93.242 4.945 268.633 1.00 29.12 ? 29 ARG B O 1 ATOM 4255 C CB . ARG B 1 29 ? -95.999 5.306 268.469 1.00 27.65 ? 29 ARG B CB 1 ATOM 4256 C CG . ARG B 1 29 ? -97.323 5.466 267.748 1.00 29.97 ? 29 ARG B CG 1 ATOM 4257 C CD . ARG B 1 29 ? -98.057 6.732 268.136 1.00 42.48 ? 29 ARG B CD 1 ATOM 4258 N NE . ARG B 1 29 ? -99.306 6.841 267.390 1.00 30.80 ? 29 ARG B NE 1 ATOM 4259 C CZ . ARG B 1 29 ? -100.463 6.336 267.803 1.00 32.59 ? 29 ARG B CZ 1 ATOM 4260 N NH1 . ARG B 1 29 ? -100.532 5.691 268.959 1.00 40.79 ? 29 ARG B NH1 1 ATOM 4261 N NH2 . ARG B 1 29 ? -101.552 6.472 267.060 1.00 38.81 ? 29 ARG B NH2 1 ATOM 4262 N N . ASN B 1 30 ? -93.400 2.734 268.997 1.00 31.26 ? 30 ASN B N 1 ATOM 4263 C CA . ASN B 1 30 ? -91.976 2.529 269.250 1.00 31.17 ? 30 ASN B CA 1 ATOM 4264 C C . ASN B 1 30 ? -91.381 1.898 267.997 1.00 32.62 ? 30 ASN B C 1 ATOM 4265 O O . ASN B 1 30 ? -91.491 0.688 267.785 1.00 63.85 ? 30 ASN B O 1 ATOM 4266 C CB . ASN B 1 30 ? -91.757 1.654 270.480 1.00 33.14 ? 30 ASN B CB 1 ATOM 4267 C CG . ASN B 1 30 ? -92.180 2.337 271.766 1.00 40.94 ? 30 ASN B CG 1 ATOM 4268 O OD1 . ASN B 1 30 ? -91.447 3.159 272.315 1.00 44.81 ? 30 ASN B OD1 1 ATOM 4269 N ND2 . ASN B 1 30 ? -93.367 1.998 272.253 1.00 39.89 ? 30 ASN B ND2 1 ATOM 4270 N N . TYR B 1 31 ? -90.760 2.722 267.162 1.00 27.26 ? 31 TYR B N 1 ATOM 4271 C CA . TYR B 1 31 ? -90.163 2.274 265.914 1.00 25.64 ? 31 TYR B CA 1 ATOM 4272 C C . TYR B 1 31 ? -88.650 2.176 266.058 1.00 24.58 ? 31 TYR B C 1 ATOM 4273 O O . TYR B 1 31 ? -88.045 2.791 266.939 1.00 25.61 ? 31 TYR B O 1 ATOM 4274 C CB . TYR B 1 31 ? -90.525 3.222 264.767 1.00 26.95 ? 31 TYR B CB 1 ATOM 4275 C CG . TYR B 1 31 ? -92.004 3.262 264.453 1.00 29.87 ? 31 TYR B CG 1 ATOM 4276 C CD1 . TYR B 1 31 ? -92.867 4.068 265.184 1.00 28.01 ? 31 TYR B CD1 1 ATOM 4277 C CD2 . TYR B 1 31 ? -92.538 2.490 263.430 1.00 38.69 ? 31 TYR B CD2 1 ATOM 4278 C CE1 . TYR B 1 31 ? -94.219 4.105 264.902 1.00 28.17 ? 31 TYR B CE1 1 ATOM 4279 C CE2 . TYR B 1 31 ? -93.890 2.521 263.141 1.00 35.12 ? 31 TYR B CE2 1 ATOM 4280 C CZ . TYR B 1 31 ? -94.725 3.330 263.881 1.00 26.67 ? 31 TYR B CZ 1 ATOM 4281 O OH . TYR B 1 31 ? -96.072 3.366 263.600 1.00 26.67 ? 31 TYR B OH 1 ATOM 4282 N N . ALA B 1 32 ? -88.041 1.390 265.174 1.00 22.63 ? 32 ALA B N 1 ATOM 4283 C CA . ALA B 1 32 ? -86.602 1.169 265.220 1.00 19.80 ? 32 ALA B CA 1 ATOM 4284 C C . ALA B 1 32 ? -86.069 0.997 263.808 1.00 21.13 ? 32 ALA B C 1 ATOM 4285 O O . ALA B 1 32 ? -86.612 0.206 263.030 1.00 25.09 ? 32 ALA B O 1 ATOM 4286 C CB . ALA B 1 32 ? -86.259 -0.060 266.069 1.00 23.35 ? 32 ALA B CB 1 ATOM 4287 N N . LEU B 1 33 ? -85.010 1.741 263.482 1.00 23.41 ? 33 LEU B N 1 ATOM 4288 C CA . LEU B 1 33 ? -84.346 1.566 262.196 1.00 25.31 ? 33 LEU B CA 1 ATOM 4289 C C . LEU B 1 33 ? -83.633 0.224 262.100 1.00 25.43 ? 33 LEU B C 1 ATOM 4290 O O . LEU B 1 33 ? -83.405 -0.266 260.989 1.00 27.64 ? 33 LEU B O 1 ATOM 4291 C CB . LEU B 1 33 ? -83.354 2.706 261.957 1.00 21.33 ? 33 LEU B CB 1 ATOM 4292 C CG . LEU B 1 33 ? -83.958 4.062 261.590 1.00 21.94 ? 33 LEU B CG 1 ATOM 4293 C CD1 . LEU B 1 33 ? -82.999 5.192 261.928 1.00 24.20 ? 33 LEU B CD1 1 ATOM 4294 C CD2 . LEU B 1 33 ? -84.330 4.099 260.115 1.00 25.90 ? 33 LEU B CD2 1 ATOM 4295 N N . VAL B 1 34 ? -83.274 -0.372 263.234 1.00 24.19 ? 34 VAL B N 1 ATOM 4296 C CA . VAL B 1 34 ? -82.677 -1.703 263.290 1.00 24.49 ? 34 VAL B CA 1 ATOM 4297 C C . VAL B 1 34 ? -83.446 -2.468 264.360 1.00 24.06 ? 34 VAL B C 1 ATOM 4298 O O . VAL B 1 34 ? -83.206 -2.283 265.558 1.00 27.37 ? 34 VAL B O 1 ATOM 4299 C CB . VAL B 1 34 ? -81.177 -1.666 263.608 1.00 26.37 ? 34 VAL B CB 1 ATOM 4300 C CG1 . VAL B 1 34 ? -80.601 -3.074 263.608 1.00 32.37 ? 34 VAL B CG1 1 ATOM 4301 C CG2 . VAL B 1 34 ? -80.437 -0.781 262.614 1.00 26.53 ? 34 VAL B CG2 1 ATOM 4302 N N . GLU B 1 35 ? -84.376 -3.321 263.937 1.00 23.41 ? 35 GLU B N 1 ATOM 4303 C CA . GLU B 1 35 ? -85.197 -4.067 264.880 1.00 24.96 ? 35 GLU B CA 1 ATOM 4304 C C . GLU B 1 35 ? -84.406 -5.209 265.503 1.00 24.58 ? 35 GLU B C 1 ATOM 4305 O O . GLU B 1 35 ? -83.563 -5.830 264.851 1.00 25.67 ? 35 GLU B O 1 ATOM 4306 C CB . GLU B 1 35 ? -86.447 -4.617 264.192 1.00 31.24 ? 35 GLU B CB 1 ATOM 4307 C CG . GLU B 1 35 ? -87.420 -3.552 263.718 1.00 37.18 ? 35 GLU B CG 1 ATOM 4308 C CD . GLU B 1 35 ? -88.748 -4.138 263.284 1.00 47.10 ? 35 GLU B CD 1 ATOM 4309 O OE1 . GLU B 1 35 ? -89.229 -5.078 263.952 1.00 66.34 ? 35 GLU B OE1 1 ATOM 4310 O OE2 . GLU B 1 35 ? -89.317 -3.657 262.283 1.00 78.01 ? 35 GLU B OE2 1 ATOM 4311 N N . ILE B 1 36 ? -84.691 -5.486 266.773 1.00 26.29 ? 36 ILE B N 1 ATOM 4312 C CA . ILE B 1 36 ? -84.025 -6.537 267.533 1.00 25.77 ? 36 ILE B CA 1 ATOM 4313 C C . ILE B 1 36 ? -85.084 -7.542 267.959 1.00 22.95 ? 36 ILE B C 1 ATOM 4314 O O . ILE B 1 36 ? -85.966 -7.222 268.766 1.00 23.54 ? 36 ILE B O 1 ATOM 4315 C CB . ILE B 1 36 ? -83.275 -5.984 268.751 1.00 25.29 ? 36 ILE B CB 1 ATOM 4316 C CG1 . ILE B 1 36 ? -82.147 -5.052 268.307 1.00 30.50 ? 36 ILE B CG1 1 ATOM 4317 C CG2 . ILE B 1 36 ? -82.732 -7.121 269.602 1.00 25.05 ? 36 ILE B CG2 1 ATOM 4318 C CD1 . ILE B 1 36 ? -81.125 -5.715 267.414 1.00 22.86 ? 36 ILE B CD1 1 ATOM 4319 N N . ASN B 1 37 ? -85.004 -8.755 267.418 1.00 23.48 ? 37 ASN B N 1 ATOM 4320 C CA . ASN B 1 37 ? -85.904 -9.833 267.810 1.00 23.22 ? 37 ASN B CA 1 ATOM 4321 C C . ASN B 1 37 ? -85.404 -10.400 269.132 1.00 23.24 ? 37 ASN B C 1 ATOM 4322 O O . ASN B 1 37 ? -84.358 -11.054 269.177 1.00 26.48 ? 37 ASN B O 1 ATOM 4323 C CB . ASN B 1 37 ? -85.956 -10.901 266.719 1.00 20.16 ? 37 ASN B CB 1 ATOM 4324 C CG . ASN B 1 37 ? -86.890 -12.057 267.056 1.00 24.44 ? 37 ASN B CG 1 ATOM 4325 O OD1 . ASN B 1 37 ? -87.320 -12.227 268.197 1.00 31.73 ? 37 ASN B OD1 1 ATOM 4326 N ND2 . ASN B 1 37 ? -87.202 -12.865 266.050 1.00 25.64 ? 37 ASN B ND2 1 ATOM 4327 N N . TYR B 1 38 ? -86.147 -10.153 270.209 1.00 23.52 ? 38 TYR B N 1 ATOM 4328 C CA . TYR B 1 38 ? -85.725 -10.567 271.540 1.00 29.40 ? 38 TYR B CA 1 ATOM 4329 C C . TYR B 1 38 ? -85.952 -12.048 271.812 1.00 37.68 ? 38 TYR B C 1 ATOM 4330 O O . TYR B 1 38 ? -85.667 -12.506 272.924 1.00 36.15 ? 38 TYR B O 1 ATOM 4331 C CB . TYR B 1 38 ? -86.439 -9.728 272.602 1.00 25.47 ? 38 TYR B CB 1 ATOM 4332 C CG . TYR B 1 38 ? -85.896 -8.323 272.711 1.00 24.63 ? 38 TYR B CG 1 ATOM 4333 C CD1 . TYR B 1 38 ? -84.886 -8.020 273.611 1.00 29.35 ? 38 TYR B CD1 1 ATOM 4334 C CD2 . TYR B 1 38 ? -86.388 -7.302 271.909 1.00 26.05 ? 38 TYR B CD2 1 ATOM 4335 C CE1 . TYR B 1 38 ? -84.381 -6.742 273.713 1.00 32.88 ? 38 TYR B CE1 1 ATOM 4336 C CE2 . TYR B 1 38 ? -85.890 -6.017 272.005 1.00 27.91 ? 38 TYR B CE2 1 ATOM 4337 C CZ . TYR B 1 38 ? -84.887 -5.744 272.910 1.00 30.07 ? 38 TYR B CZ 1 ATOM 4338 O OH . TYR B 1 38 ? -84.384 -4.469 273.016 1.00 33.47 ? 38 TYR B OH 1 ATOM 4339 N N . GLU B 1 39 ? -86.457 -12.804 270.839 1.00 25.54 ? 39 GLU B N 1 ATOM 4340 C CA . GLU B 1 39 ? -86.571 -14.249 270.963 1.00 25.44 ? 39 GLU B CA 1 ATOM 4341 C C . GLU B 1 39 ? -85.608 -15.001 270.058 1.00 25.91 ? 39 GLU B C 1 ATOM 4342 O O . GLU B 1 39 ? -85.486 -16.224 270.193 1.00 36.44 ? 39 GLU B O 1 ATOM 4343 C CB . GLU B 1 39 ? -88.007 -14.702 270.660 1.00 29.43 ? 39 GLU B CB 1 ATOM 4344 C CG . GLU B 1 39 ? -89.056 -14.118 271.593 1.00 28.91 ? 39 GLU B CG 1 ATOM 4345 C CD . GLU B 1 39 ? -88.945 -14.653 273.008 1.00 35.14 ? 39 GLU B CD 1 ATOM 4346 O OE1 . GLU B 1 39 ? -88.364 -15.743 273.192 1.00 33.37 ? 39 GLU B OE1 1 ATOM 4347 O OE2 . GLU B 1 39 ? -89.442 -13.984 273.938 1.00 33.64 ? 39 GLU B OE2 1 ATOM 4348 N N . ALA B 1 40 ? -84.923 -14.311 269.152 1.00 25.33 ? 40 ALA B N 1 ATOM 4349 C CA . ALA B 1 40 ? -84.026 -14.965 268.214 1.00 28.87 ? 40 ALA B CA 1 ATOM 4350 C C . ALA B 1 40 ? -82.719 -15.354 268.891 1.00 34.88 ? 40 ALA B C 1 ATOM 4351 O O . ALA B 1 40 ? -82.242 -14.683 269.811 1.00 30.87 ? 40 ALA B O 1 ATOM 4352 C CB . ALA B 1 40 ? -83.739 -14.054 267.022 1.00 31.56 ? 40 ALA B CB 1 ATOM 4353 N N . THR B 1 41 ? -82.140 -16.457 268.421 1.00 52.44 ? 41 THR B N 1 ATOM 4354 C CA . THR B 1 41 ? -80.844 -16.925 268.891 1.00 32.69 ? 41 THR B CA 1 ATOM 4355 C C . THR B 1 41 ? -79.739 -16.774 267.859 1.00 28.87 ? 41 THR B C 1 ATOM 4356 O O . THR B 1 41 ? -78.586 -16.563 268.237 1.00 39.96 ? 41 THR B O 1 ATOM 4357 C CB . THR B 1 41 ? -80.929 -18.397 269.314 1.00 35.68 ? 41 THR B CB 1 ATOM 4358 O OG1 . THR B 1 41 ? -81.790 -19.106 268.414 1.00 42.79 ? 41 THR B OG1 1 ATOM 4359 C CG2 . THR B 1 41 ? -81.479 -18.513 270.727 1.00 36.97 ? 41 THR B CG2 1 ATOM 4360 N N . ALA B 1 42 ? -80.063 -16.873 266.574 1.00 28.96 ? 42 ALA B N 1 ATOM 4361 C CA . ALA B 1 42 ? -79.075 -16.683 265.524 1.00 27.07 ? 42 ALA B CA 1 ATOM 4362 C C . ALA B 1 42 ? -78.926 -15.203 265.194 1.00 29.34 ? 42 ALA B C 1 ATOM 4363 O O . ALA B 1 42 ? -79.858 -14.411 265.356 1.00 33.54 ? 42 ALA B O 1 ATOM 4364 C CB . ALA B 1 42 ? -79.466 -17.462 264.268 1.00 33.17 ? 42 ALA B CB 1 ATOM 4365 N N . TYR B 1 43 ? -77.732 -14.835 264.724 1.00 30.38 ? 43 TYR B N 1 ATOM 4366 C CA . TYR B 1 43 ? -77.466 -13.437 264.404 1.00 30.75 ? 43 TYR B CA 1 ATOM 4367 C C . TYR B 1 43 ? -78.273 -12.969 263.200 1.00 31.74 ? 43 TYR B C 1 ATOM 4368 O O . TYR B 1 43 ? -78.633 -11.789 263.120 1.00 41.57 ? 43 TYR B O 1 ATOM 4369 C CB . TYR B 1 43 ? -75.972 -13.230 264.153 1.00 29.91 ? 43 TYR B CB 1 ATOM 4370 C CG . TYR B 1 43 ? -75.571 -11.780 264.004 1.00 25.68 ? 43 TYR B CG 1 ATOM 4371 C CD1 . TYR B 1 43 ? -75.303 -10.995 265.117 1.00 22.46 ? 43 TYR B CD1 1 ATOM 4372 C CD2 . TYR B 1 43 ? -75.461 -11.196 262.749 1.00 26.73 ? 43 TYR B CD2 1 ATOM 4373 C CE1 . TYR B 1 43 ? -74.937 -9.670 264.984 1.00 22.76 ? 43 TYR B CE1 1 ATOM 4374 C CE2 . TYR B 1 43 ? -75.095 -9.873 262.607 1.00 25.93 ? 43 TYR B CE2 1 ATOM 4375 C CZ . TYR B 1 43 ? -74.835 -9.114 263.728 1.00 23.20 ? 43 TYR B CZ 1 ATOM 4376 O OH . TYR B 1 43 ? -74.470 -7.795 263.592 1.00 22.84 ? 43 TYR B OH 1 ATOM 4377 N N . GLU B 1 44 ? -78.565 -13.869 262.258 1.00 26.90 ? 44 GLU B N 1 ATOM 4378 C CA . GLU B 1 44 ? -79.321 -13.477 261.074 1.00 29.86 ? 44 GLU B CA 1 ATOM 4379 C C . GLU B 1 44 ? -80.762 -13.120 261.415 1.00 28.27 ? 44 GLU B C 1 ATOM 4380 O O . GLU B 1 44 ? -81.371 -12.290 260.730 1.00 33.18 ? 44 GLU B O 1 ATOM 4381 C CB . GLU B 1 44 ? -79.282 -14.592 260.031 1.00 45.59 ? 44 GLU B CB 1 ATOM 4382 C CG . GLU B 1 44 ? -77.916 -14.798 259.399 1.00 34.15 ? 44 GLU B CG 1 ATOM 4383 C CD . GLU B 1 44 ? -77.673 -13.866 258.230 1.00 37.62 ? 44 GLU B CD 1 ATOM 4384 O OE1 . GLU B 1 44 ? -78.659 -13.440 257.593 1.00 34.91 ? 44 GLU B OE1 1 ATOM 4385 O OE2 . GLU B 1 44 ? -76.496 -13.556 257.949 1.00 74.60 ? 44 GLU B OE2 1 ATOM 4386 N N . ASN B 1 45 ? -81.323 -13.730 262.456 1.00 26.66 ? 45 ASN B N 1 ATOM 4387 C CA . ASN B 1 45 ? -82.671 -13.417 262.909 1.00 26.43 ? 45 ASN B CA 1 ATOM 4388 C C . ASN B 1 45 ? -82.690 -12.417 264.056 1.00 26.12 ? 45 ASN B C 1 ATOM 4389 O O . ASN B 1 45 ? -83.773 -11.998 264.476 1.00 27.15 ? 45 ASN B O 1 ATOM 4390 C CB . ASN B 1 45 ? -83.400 -14.698 263.331 1.00 28.31 ? 45 ASN B CB 1 ATOM 4391 C CG . ASN B 1 45 ? -83.444 -15.733 262.227 1.00 33.10 ? 45 ASN B CG 1 ATOM 4392 O OD1 . ASN B 1 45 ? -83.448 -15.395 261.044 1.00 30.74 ? 45 ASN B OD1 1 ATOM 4393 N ND2 . ASN B 1 45 ? -83.478 -17.005 262.609 1.00 60.67 ? 45 ASN B ND2 1 ATOM 4394 N N . LEU B 1 46 ? -81.524 -12.024 264.568 1.00 26.52 ? 46 LEU B N 1 ATOM 4395 C CA . LEU B 1 46 ? -81.475 -11.092 265.689 1.00 27.03 ? 46 LEU B CA 1 ATOM 4396 C C . LEU B 1 46 ? -81.779 -9.666 265.247 1.00 23.96 ? 46 LEU B C 1 ATOM 4397 O O . LEU B 1 46 ? -82.604 -8.981 265.861 1.00 22.31 ? 46 LEU B O 1 ATOM 4398 C CB . LEU B 1 46 ? -80.105 -11.158 266.366 1.00 26.01 ? 46 LEU B CB 1 ATOM 4399 C CG . LEU B 1 46 ? -79.842 -10.096 267.435 1.00 26.54 ? 46 LEU B CG 1 ATOM 4400 C CD1 . LEU B 1 46 ? -80.800 -10.260 268.602 1.00 25.51 ? 46 LEU B CD1 1 ATOM 4401 C CD2 . LEU B 1 46 ? -78.398 -10.151 267.908 1.00 24.67 ? 46 LEU B CD2 1 ATOM 4402 N N . ILE B 1 47 ? -81.126 -9.205 264.186 1.00 27.14 ? 47 ILE B N 1 ATOM 4403 C CA . ILE B 1 47 ? -81.228 -7.819 263.755 1.00 29.65 ? 47 ILE B CA 1 ATOM 4404 C C . ILE B 1 47 ? -82.053 -7.739 262.477 1.00 32.14 ? 47 ILE B C 1 ATOM 4405 O O . ILE B 1 47 ? -82.204 -8.712 261.732 1.00 35.21 ? 47 ILE B O 1 ATOM 4406 C CB . ILE B 1 47 ? -79.839 -7.182 263.546 1.00 23.12 ? 47 ILE B CB 1 ATOM 4407 C CG1 . ILE B 1 47 ? -79.102 -7.877 262.401 1.00 25.73 ? 47 ILE B CG1 1 ATOM 4408 C CG2 . ILE B 1 47 ? -79.023 -7.263 264.822 1.00 28.93 ? 47 ILE B CG2 1 ATOM 4409 C CD1 . ILE B 1 47 ? -77.765 -7.253 262.071 1.00 28.80 ? 47 ILE B CD1 1 ATOM 4410 N N . LYS B 1 48 ? -82.597 -6.550 262.232 1.00 34.00 ? 48 LYS B N 1 ATOM 4411 C CA . LYS B 1 48 ? -83.328 -6.248 261.001 1.00 28.47 ? 48 LYS B CA 1 ATOM 4412 C C . LYS B 1 48 ? -83.007 -4.819 260.597 1.00 26.25 ? 48 LYS B C 1 ATOM 4413 O O . LYS B 1 48 ? -83.753 -3.882 260.906 1.00 25.50 ? 48 LYS B O 1 ATOM 4414 C CB . LYS B 1 48 ? -84.835 -6.446 261.183 1.00 30.23 ? 48 LYS B CB 1 ATOM 4415 C CG . LYS B 1 48 ? -85.628 -6.342 259.887 1.00 36.40 ? 48 LYS B CG 1 ATOM 4416 C CD . LYS B 1 48 ? -87.113 -6.565 260.119 1.00 46.52 ? 48 LYS B CD 1 ATOM 4417 C CE . LYS B 1 48 ? -87.814 -6.981 258.834 1.00 51.80 ? 48 LYS B CE 1 ATOM 4418 N NZ . LYS B 1 48 ? -88.912 -7.956 259.085 1.00 46.83 ? 48 LYS B NZ 1 ATOM 4419 N N . PRO B 1 49 ? -81.885 -4.611 259.910 1.00 27.06 ? 49 PRO B N 1 ATOM 4420 C CA . PRO B 1 49 ? -81.520 -3.252 259.493 1.00 33.41 ? 49 PRO B CA 1 ATOM 4421 C C . PRO B 1 49 ? -82.471 -2.727 258.429 1.00 29.80 ? 49 PRO B C 1 ATOM 4422 O O . PRO B 1 49 ? -82.837 -3.437 257.490 1.00 27.47 ? 49 PRO B O 1 ATOM 4423 C CB . PRO B 1 49 ? -80.099 -3.417 258.939 1.00 31.99 ? 49 PRO B CB 1 ATOM 4424 C CG . PRO B 1 49 ? -79.615 -4.731 259.482 1.00 25.54 ? 49 PRO B CG 1 ATOM 4425 C CD . PRO B 1 49 ? -80.834 -5.588 259.587 1.00 23.73 ? 49 PRO B CD 1 ATOM 4426 N N . LYS B 1 50 ? -82.868 -1.466 258.584 1.00 27.43 ? 50 LYS B N 1 ATOM 4427 C CA . LYS B 1 50 ? -83.785 -0.815 257.658 1.00 29.57 ? 50 LYS B CA 1 ATOM 4428 C C . LYS B 1 50 ? -83.177 0.490 257.172 1.00 33.47 ? 50 LYS B C 1 ATOM 4429 O O . LYS B 1 50 ? -82.656 1.273 257.974 1.00 38.15 ? 50 LYS B O 1 ATOM 4430 C CB . LYS B 1 50 ? -85.143 -0.545 258.312 1.00 31.10 ? 50 LYS B CB 1 ATOM 4431 C CG . LYS B 1 50 ? -85.935 -1.793 258.648 1.00 35.03 ? 50 LYS B CG 1 ATOM 4432 C CD . LYS B 1 50 ? -87.314 -1.436 259.169 1.00 31.67 ? 50 LYS B CD 1 ATOM 4433 C CE . LYS B 1 50 ? -88.083 -2.678 259.574 1.00 44.25 ? 50 LYS B CE 1 ATOM 4434 N NZ . LYS B 1 50 ? -89.455 -2.352 260.052 1.00 42.08 ? 50 LYS B NZ 1 ATOM 4435 N N . GLU B 1 51 ? -83.242 0.717 255.858 1.00 35.23 ? 51 GLU B N 1 ATOM 4436 C CA . GLU B 1 51 ? -82.850 2.011 255.310 1.00 43.82 ? 51 GLU B CA 1 ATOM 4437 C C . GLU B 1 51 ? -83.720 3.124 255.876 1.00 37.34 ? 51 GLU B C 1 ATOM 4438 O O . GLU B 1 51 ? -83.226 4.212 256.194 1.00 36.87 ? 51 GLU B O 1 ATOM 4439 C CB . GLU B 1 51 ? -82.946 1.984 253.784 1.00 50.98 ? 51 GLU B CB 1 ATOM 4440 C CG . GLU B 1 51 ? -81.980 1.030 253.096 1.00 56.10 ? 51 GLU B CG 1 ATOM 4441 C CD . GLU B 1 51 ? -80.545 1.526 253.108 1.00 76.77 ? 51 GLU B CD 1 ATOM 4442 O OE1 . GLU B 1 51 ? -80.308 2.674 253.541 1.00 78.51 ? 51 GLU B OE1 1 ATOM 4443 O OE2 . GLU B 1 51 ? -79.653 0.767 252.677 1.00 67.24 ? 51 GLU B OE2 1 ATOM 4444 N N . GLN B 1 52 ? -85.017 2.864 256.015 1.00 35.80 ? 52 GLN B N 1 ATOM 4445 C CA . GLN B 1 52 ? -85.972 3.849 256.493 1.00 33.89 ? 52 GLN B CA 1 ATOM 4446 C C . GLN B 1 52 ? -86.998 3.156 257.376 1.00 34.15 ? 52 GLN B C 1 ATOM 4447 O O . GLN B 1 52 ? -87.121 1.929 257.374 1.00 60.63 ? 52 GLN B O 1 ATOM 4448 C CB . GLN B 1 52 ? -86.677 4.555 255.329 1.00 37.05 ? 52 GLN B CB 1 ATOM 4449 C CG . GLN B 1 52 ? -87.649 3.654 254.582 1.00 34.76 ? 52 GLN B CG 1 ATOM 4450 C CD . GLN B 1 52 ? -88.013 4.189 253.213 1.00 37.60 ? 52 GLN B CD 1 ATOM 4451 O OE1 . GLN B 1 52 ? -87.175 4.755 252.512 1.00 65.26 ? 52 GLN B OE1 1 ATOM 4452 N NE2 . GLN B 1 52 ? -89.270 4.011 252.824 1.00 40.52 ? 52 GLN B NE2 1 ATOM 4453 N N . VAL B 1 53 ? -87.737 3.959 258.133 1.00 30.33 ? 53 VAL B N 1 ATOM 4454 C CA . VAL B 1 53 ? -88.855 3.478 258.932 1.00 32.31 ? 53 VAL B CA 1 ATOM 4455 C C . VAL B 1 53 ? -90.079 4.311 258.577 1.00 47.26 ? 53 VAL B C 1 ATOM 4456 O O . VAL B 1 53 ? -89.971 5.517 258.327 1.00 50.80 ? 53 VAL B O 1 ATOM 4457 C CB . VAL B 1 53 ? -88.551 3.533 260.446 1.00 27.08 ? 53 VAL B CB 1 ATOM 4458 C CG1 . VAL B 1 53 ? -88.437 4.970 260.933 1.00 28.35 ? 53 VAL B CG1 1 ATOM 4459 C CG2 . VAL B 1 53 ? -89.609 2.773 261.233 1.00 31.72 ? 53 VAL B CG2 1 ATOM 4460 N N . ASP B 1 54 ? -91.238 3.661 258.523 1.00 29.15 ? 54 ASP B N 1 ATOM 4461 C CA . ASP B 1 54 ? -92.485 4.300 258.118 1.00 29.09 ? 54 ASP B CA 1 ATOM 4462 C C . ASP B 1 54 ? -93.365 4.480 259.348 1.00 30.34 ? 54 ASP B C 1 ATOM 4463 O O . ASP B 1 54 ? -93.926 3.509 259.865 1.00 38.81 ? 54 ASP B O 1 ATOM 4464 C CB . ASP B 1 54 ? -93.197 3.477 257.047 1.00 32.30 ? 54 ASP B CB 1 ATOM 4465 C CG . ASP B 1 54 ? -92.442 3.452 255.734 1.00 32.71 ? 54 ASP B CG 1 ATOM 4466 O OD1 . ASP B 1 54 ? -92.421 4.489 255.039 1.00 32.33 ? 54 ASP B OD1 1 ATOM 4467 O OD2 . ASP B 1 54 ? -91.871 2.394 255.395 1.00 38.55 ? 54 ASP B OD2 1 ATOM 4468 N N . VAL B 1 55 ? -93.481 5.721 259.813 1.00 30.09 ? 55 VAL B N 1 ATOM 4469 C CA . VAL B 1 55 ? -94.376 6.048 260.918 1.00 24.55 ? 55 VAL B CA 1 ATOM 4470 C C . VAL B 1 55 ? -95.790 6.148 260.356 1.00 26.44 ? 55 VAL B C 1 ATOM 4471 O O . VAL B 1 55 ? -96.104 7.068 259.598 1.00 43.04 ? 55 VAL B O 1 ATOM 4472 C CB . VAL B 1 55 ? -93.961 7.348 261.616 1.00 23.74 ? 55 VAL B CB 1 ATOM 4473 C CG1 . VAL B 1 55 ? -95.016 7.765 262.627 1.00 25.73 ? 55 VAL B CG1 1 ATOM 4474 C CG2 . VAL B 1 55 ? -92.613 7.172 262.295 1.00 25.97 ? 55 VAL B CG2 1 ATOM 4475 N N . GLN B 1 56 ? -96.642 5.196 260.720 1.00 26.98 ? 56 GLN B N 1 ATOM 4476 C CA . GLN B 1 56 ? -98.018 5.152 260.250 1.00 26.43 ? 56 GLN B CA 1 ATOM 4477 C C . GLN B 1 56 ? -98.953 5.658 261.340 1.00 28.22 ? 56 GLN B C 1 ATOM 4478 O O . GLN B 1 56 ? -98.814 5.291 262.511 1.00 31.28 ? 56 GLN B O 1 ATOM 4479 C CB . GLN B 1 56 ? -98.409 3.732 259.839 1.00 26.68 ? 56 GLN B CB 1 ATOM 4480 C CG . GLN B 1 56 ? -97.708 3.240 258.584 1.00 31.89 ? 56 GLN B CG 1 ATOM 4481 C CD . GLN B 1 56 ? -97.975 1.776 258.303 1.00 34.71 ? 56 GLN B CD 1 ATOM 4482 O OE1 . GLN B 1 56 ? -99.090 1.392 257.949 1.00 30.32 ? 56 GLN B OE1 1 ATOM 4483 N NE2 . GLN B 1 56 ? -96.950 0.947 258.462 1.00 33.76 ? 56 GLN B NE2 1 ATOM 4484 N N . VAL B 1 57 ? -99.903 6.503 260.948 1.00 25.79 ? 57 VAL B N 1 ATOM 4485 C CA . VAL B 1 57 ? -100.852 7.102 261.879 1.00 23.74 ? 57 VAL B CA 1 ATOM 4486 C C . VAL B 1 57 ? -102.232 7.107 261.238 1.00 25.84 ? 57 VAL B C 1 ATOM 4487 O O . VAL B 1 57 ? -102.386 7.505 260.078 1.00 29.19 ? 57 VAL B O 1 ATOM 4488 C CB . VAL B 1 57 ? -100.429 8.528 262.287 1.00 24.30 ? 57 VAL B CB 1 ATOM 4489 C CG1 . VAL B 1 57 ? -100.074 9.358 261.065 1.00 32.65 ? 57 VAL B CG1 1 ATOM 4490 C CG2 . VAL B 1 57 ? -101.528 9.202 263.092 1.00 30.84 ? 57 VAL B CG2 1 ATOM 4491 N N . SER B 1 58 ? -103.231 6.652 261.988 1.00 27.29 ? 58 SER B N 1 ATOM 4492 C CA . SER B 1 58 ? -104.618 6.668 261.553 1.00 34.27 ? 58 SER B CA 1 ATOM 4493 C C . SER B 1 58 ? -105.467 7.316 262.637 1.00 45.09 ? 58 SER B C 1 ATOM 4494 O O . SER B 1 58 ? -105.075 7.379 263.806 1.00 40.32 ? 58 SER B O 1 ATOM 4495 C CB . SER B 1 58 ? -105.131 5.255 261.244 1.00 37.10 ? 58 SER B CB 1 ATOM 4496 O OG . SER B 1 58 ? -106.402 5.302 260.622 1.00 65.99 ? 58 SER B OG 1 ATOM 4497 N N . TRP B 1 59 ? -106.642 7.798 262.241 1.00 47.92 ? 59 TRP B N 1 ATOM 4498 C CA . TRP B 1 59 ? -107.483 8.559 263.152 1.00 38.55 ? 59 TRP B CA 1 ATOM 4499 C C . TRP B 1 59 ? -108.945 8.410 262.755 1.00 39.89 ? 59 TRP B C 1 ATOM 4500 O O . TRP B 1 59 ? -109.274 7.955 261.656 1.00 44.56 ? 59 TRP B O 1 ATOM 4501 C CB . TRP B 1 59 ? -107.083 10.038 263.167 1.00 41.82 ? 59 TRP B CB 1 ATOM 4502 C CG . TRP B 1 59 ? -107.318 10.730 261.857 1.00 41.62 ? 59 TRP B CG 1 ATOM 4503 C CD1 . TRP B 1 59 ? -108.425 11.438 261.490 1.00 39.36 ? 59 TRP B CD1 1 ATOM 4504 C CD2 . TRP B 1 59 ? -106.426 10.771 260.736 1.00 37.43 ? 59 TRP B CD2 1 ATOM 4505 N NE1 . TRP B 1 59 ? -108.277 11.920 260.212 1.00 34.21 ? 59 TRP B NE1 1 ATOM 4506 C CE2 . TRP B 1 59 ? -107.058 11.525 259.727 1.00 36.52 ? 59 TRP B CE2 1 ATOM 4507 C CE3 . TRP B 1 59 ? -105.155 10.245 260.488 1.00 35.97 ? 59 TRP B CE3 1 ATOM 4508 C CZ2 . TRP B 1 59 ? -106.463 11.766 258.492 1.00 35.47 ? 59 TRP B CZ2 1 ATOM 4509 C CZ3 . TRP B 1 59 ? -104.566 10.486 259.260 1.00 35.38 ? 59 TRP B CZ3 1 ATOM 4510 C CH2 . TRP B 1 59 ? -105.219 11.239 258.278 1.00 34.44 ? 59 TRP B CH2 1 ATOM 4511 N N . ASN B 1 60 ? -109.821 8.801 263.676 1.00 38.80 ? 60 ASN B N 1 ATOM 4512 C CA . ASN B 1 60 ? -111.252 8.893 263.437 1.00 40.55 ? 60 ASN B CA 1 ATOM 4513 C C . ASN B 1 60 ? -111.724 10.305 263.757 1.00 41.24 ? 60 ASN B C 1 ATOM 4514 O O . ASN B 1 60 ? -111.033 11.075 264.430 1.00 41.50 ? 60 ASN B O 1 ATOM 4515 C CB . ASN B 1 60 ? -112.031 7.872 264.277 1.00 43.38 ? 60 ASN B CB 1 ATOM 4516 C CG . ASN B 1 60 ? -111.834 6.449 263.795 1.00 52.35 ? 60 ASN B CG 1 ATOM 4517 O OD1 . ASN B 1 60 ? -111.707 6.200 262.596 1.00 59.88 ? 60 ASN B OD1 1 ATOM 4518 N ND2 . ASN B 1 60 ? -111.813 5.506 264.729 1.00 56.23 ? 60 ASN B ND2 1 ATOM 4519 N N . VAL B 1 61 ? -112.914 10.641 263.267 1.00 42.11 ? 61 VAL B N 1 ATOM 4520 C CA . VAL B 1 61 ? -113.481 11.975 263.416 1.00 41.37 ? 61 VAL B CA 1 ATOM 4521 C C . VAL B 1 61 ? -114.801 11.863 264.164 1.00 40.60 ? 61 VAL B C 1 ATOM 4522 O O . VAL B 1 61 ? -115.648 11.030 263.819 1.00 39.87 ? 61 VAL B O 1 ATOM 4523 C CB . VAL B 1 61 ? -113.685 12.661 262.053 1.00 44.51 ? 61 VAL B CB 1 ATOM 4524 C CG1 . VAL B 1 61 ? -114.193 14.079 262.247 1.00 65.56 ? 61 VAL B CG1 1 ATOM 4525 C CG2 . VAL B 1 61 ? -112.389 12.656 261.257 1.00 51.23 ? 61 VAL B CG2 1 ATOM 4526 N N . TRP B 1 62 ? -114.974 12.700 265.185 1.00 40.98 ? 62 TRP B N 1 ATOM 4527 C CA . TRP B 1 62 ? -116.201 12.754 265.964 1.00 53.76 ? 62 TRP B CA 1 ATOM 4528 C C . TRP B 1 62 ? -116.813 14.144 265.863 1.00 48.50 ? 62 TRP B C 1 ATOM 4529 O O . TRP B 1 62 ? -116.102 15.144 265.722 1.00 48.29 ? 62 TRP B O 1 ATOM 4530 C CB . TRP B 1 62 ? -115.953 12.415 267.440 1.00 47.24 ? 62 TRP B CB 1 ATOM 4531 C CG . TRP B 1 62 ? -115.248 11.111 267.671 1.00 44.45 ? 62 TRP B CG 1 ATOM 4532 C CD1 . TRP B 1 62 ? -115.139 10.068 266.798 1.00 55.49 ? 62 TRP B CD1 1 ATOM 4533 C CD2 . TRP B 1 62 ? -114.555 10.713 268.859 1.00 56.41 ? 62 TRP B CD2 1 ATOM 4534 N NE1 . TRP B 1 62 ? -114.418 9.047 267.368 1.00 46.68 ? 62 TRP B NE1 1 ATOM 4535 C CE2 . TRP B 1 62 ? -114.049 9.418 268.634 1.00 41.59 ? 62 TRP B CE2 1 ATOM 4536 C CE3 . TRP B 1 62 ? -114.314 11.326 270.092 1.00 50.39 ? 62 TRP B CE3 1 ATOM 4537 C CZ2 . TRP B 1 62 ? -113.315 8.727 269.594 1.00 43.82 ? 62 TRP B CZ2 1 ATOM 4538 C CZ3 . TRP B 1 62 ? -113.585 10.637 271.045 1.00 44.83 ? 62 TRP B CZ3 1 ATOM 4539 C CH2 . TRP B 1 62 ? -113.095 9.351 270.791 1.00 43.23 ? 62 TRP B CH2 1 ATOM 4540 N N . ASN B 1 63 ? -118.144 14.191 265.941 1.00 50.37 ? 63 ASN B N 1 ATOM 4541 C CA . ASN B 1 63 ? -118.911 15.437 265.953 1.00 49.14 ? 63 ASN B CA 1 ATOM 4542 C C . ASN B 1 63 ? -118.604 16.274 264.706 1.00 52.39 ? 63 ASN B C 1 ATOM 4543 O O . ASN B 1 63 ? -117.942 17.311 264.753 1.00 51.81 ? 63 ASN B O 1 ATOM 4544 C CB . ASN B 1 63 ? -118.639 16.225 267.243 1.00 64.67 ? 63 ASN B CB 1 ATOM 4545 C CG . ASN B 1 63 ? -119.386 17.549 267.297 1.00 67.86 ? 63 ASN B CG 1 ATOM 4546 O OD1 . ASN B 1 63 ? -120.375 17.749 266.592 1.00 54.53 ? 63 ASN B OD1 1 ATOM 4547 N ND2 . ASN B 1 63 ? -118.906 18.465 268.132 1.00 58.53 ? 63 ASN B ND2 1 ATOM 4548 N N . GLY B 1 64 ? -119.100 15.780 263.581 1.00 53.23 ? 64 GLY B N 1 ATOM 4549 C CA . GLY B 1 64 ? -119.026 16.499 262.327 1.00 65.39 ? 64 GLY B CA 1 ATOM 4550 C C . GLY B 1 64 ? -118.327 15.698 261.249 1.00 61.50 ? 64 GLY B C 1 ATOM 4551 O O . GLY B 1 64 ? -118.060 14.501 261.389 1.00 53.69 ? 64 GLY B O 1 ATOM 4552 N N . ASP B 1 65 ? -118.023 16.389 260.153 1.00 61.69 ? 65 ASP B N 1 ATOM 4553 C CA . ASP B 1 65 ? -117.434 15.778 258.975 1.00 54.84 ? 65 ASP B CA 1 ATOM 4554 C C . ASP B 1 65 ? -115.934 15.572 259.155 1.00 53.21 ? 65 ASP B C 1 ATOM 4555 O O . ASP B 1 65 ? -115.301 16.137 260.051 1.00 50.41 ? 65 ASP B O 1 ATOM 4556 C CB . ASP B 1 65 ? -117.695 16.641 257.741 1.00 60.14 ? 65 ASP B CB 1 ATOM 4557 C CG . ASP B 1 65 ? -117.136 18.042 257.884 1.00 65.33 ? 65 ASP B CG 1 ATOM 4558 O OD1 . ASP B 1 65 ? -117.844 18.909 258.438 1.00 65.24 ? 65 ASP B OD1 1 ATOM 4559 O OD2 . ASP B 1 65 ? -115.989 18.277 257.450 1.00 90.58 ? 65 ASP B OD2 1 ATOM 4560 N N . ILE B 1 66 ? -115.366 14.749 258.270 1.00 51.10 ? 66 ILE B N 1 ATOM 4561 C CA . ILE B 1 66 ? -113.948 14.417 258.330 1.00 47.29 ? 66 ILE B CA 1 ATOM 4562 C C . ILE B 1 66 ? -113.049 15.543 257.849 1.00 47.93 ? 66 ILE B C 1 ATOM 4563 O O . ILE B 1 66 ? -111.831 15.473 258.038 1.00 57.58 ? 66 ILE B O 1 ATOM 4564 C CB . ILE B 1 66 ? -113.662 13.149 257.501 1.00 49.88 ? 66 ILE B CB 1 ATOM 4565 C CG1 . ILE B 1 66 ? -114.088 13.363 256.047 1.00 56.99 ? 66 ILE B CG1 1 ATOM 4566 C CG2 . ILE B 1 66 ? -114.377 11.949 258.102 1.00 70.03 ? 66 ILE B CG2 1 ATOM 4567 C CD1 . ILE B 1 66 ? -113.778 12.193 255.141 1.00 48.85 ? 66 ILE B CD1 1 ATOM 4568 N N . GLY B 1 67 ? -113.612 16.578 257.232 1.00 45.12 ? 67 GLY B N 1 ATOM 4569 C CA . GLY B 1 67 ? -112.825 17.651 256.668 1.00 42.61 ? 67 GLY B CA 1 ATOM 4570 C C . GLY B 1 67 ? -112.439 17.383 255.225 1.00 42.43 ? 67 GLY B C 1 ATOM 4571 O O . GLY B 1 67 ? -112.657 16.303 254.670 1.00 43.21 ? 67 GLY B O 1 ATOM 4572 N N . ASP B 1 68 ? -111.843 18.400 254.606 1.00 46.92 ? 68 ASP B N 1 ATOM 4573 C CA . ASP B 1 68 ? -111.460 18.336 253.201 1.00 44.42 ? 68 ASP B CA 1 ATOM 4574 C C . ASP B 1 68 ? -110.009 17.926 252.991 1.00 44.16 ? 68 ASP B C 1 ATOM 4575 O O . ASP B 1 68 ? -109.715 17.167 252.063 1.00 47.76 ? 68 ASP B O 1 ATOM 4576 C CB . ASP B 1 68 ? -111.710 19.687 252.524 1.00 45.22 ? 68 ASP B CB 1 ATOM 4577 C CG . ASP B 1 68 ? -113.165 20.107 252.584 1.00 51.00 ? 68 ASP B CG 1 ATOM 4578 O OD1 . ASP B 1 68 ? -114.038 19.220 252.686 1.00 80.27 ? 68 ASP B OD1 1 ATOM 4579 O OD2 . ASP B 1 68 ? -113.436 21.325 252.523 1.00 67.29 ? 68 ASP B OD2 1 ATOM 4580 N N . ILE B 1 69 ? -109.091 18.409 253.828 1.00 38.40 ? 69 ILE B N 1 ATOM 4581 C CA . ILE B 1 69 ? -107.674 18.100 253.692 1.00 37.24 ? 69 ILE B CA 1 ATOM 4582 C C . ILE B 1 69 ? -107.096 17.843 255.078 1.00 41.10 ? 69 ILE B C 1 ATOM 4583 O O . ILE B 1 69 ? -107.542 18.417 256.076 1.00 44.57 ? 69 ILE B O 1 ATOM 4584 C CB . ILE B 1 69 ? -106.912 19.230 252.957 1.00 36.64 ? 69 ILE B CB 1 ATOM 4585 C CG1 . ILE B 1 69 ? -105.571 18.723 252.424 1.00 46.77 ? 69 ILE B CG1 1 ATOM 4586 C CG2 . ILE B 1 69 ? -106.718 20.439 253.862 1.00 41.59 ? 69 ILE B CG2 1 ATOM 4587 C CD1 . ILE B 1 69 ? -104.975 19.603 251.347 1.00 57.73 ? 69 ILE B CD1 1 ATOM 4588 N N . ALA B 1 70 ? -106.104 16.955 255.137 1.00 43.18 ? 70 ALA B N 1 ATOM 4589 C CA . ALA B 1 70 ? -105.531 16.508 256.398 1.00 38.88 ? 70 ALA B CA 1 ATOM 4590 C C . ALA B 1 70 ? -104.020 16.677 256.382 1.00 38.80 ? 70 ALA B C 1 ATOM 4591 O O . ALA B 1 70 ? -103.368 16.421 255.366 1.00 40.00 ? 70 ALA B O 1 ATOM 4592 C CB . ALA B 1 70 ? -105.887 15.043 256.680 1.00 64.17 ? 70 ALA B CB 1 ATOM 4593 N N . TYR B 1 71 ? -103.470 17.103 257.517 1.00 36.70 ? 71 TYR B N 1 ATOM 4594 C CA . TYR B 1 71 ? -102.037 17.282 257.693 1.00 33.02 ? 71 TYR B CA 1 ATOM 4595 C C . TYR B 1 71 ? -101.555 16.478 258.893 1.00 30.72 ? 71 TYR B C 1 ATOM 4596 O O . TYR B 1 71 ? -102.292 16.275 259.863 1.00 32.23 ? 71 TYR B O 1 ATOM 4597 C CB . TYR B 1 71 ? -101.673 18.760 257.898 1.00 37.12 ? 71 TYR B CB 1 ATOM 4598 C CG . TYR B 1 71 ? -102.052 19.669 256.752 1.00 38.82 ? 71 TYR B CG 1 ATOM 4599 C CD1 . TYR B 1 71 ? -101.261 19.747 255.617 1.00 38.23 ? 71 TYR B CD1 1 ATOM 4600 C CD2 . TYR B 1 71 ? -103.195 20.454 256.809 1.00 38.59 ? 71 TYR B CD2 1 ATOM 4601 C CE1 . TYR B 1 71 ? -101.599 20.574 254.566 1.00 40.40 ? 71 TYR B CE1 1 ATOM 4602 C CE2 . TYR B 1 71 ? -103.542 21.287 255.762 1.00 42.01 ? 71 TYR B CE2 1 ATOM 4603 C CZ . TYR B 1 71 ? -102.739 21.342 254.643 1.00 42.15 ? 71 TYR B CZ 1 ATOM 4604 O OH . TYR B 1 71 ? -103.073 22.166 253.596 1.00 42.67 ? 71 TYR B OH 1 ATOM 4605 N N . VAL B 1 72 ? -100.307 16.023 258.818 1.00 28.69 ? 72 VAL B N 1 ATOM 4606 C CA . VAL B 1 72 ? -99.631 15.356 259.926 1.00 27.88 ? 72 VAL B CA 1 ATOM 4607 C C . VAL B 1 72 ? -98.511 16.268 260.404 1.00 27.84 ? 72 VAL B C 1 ATOM 4608 O O . VAL B 1 72 ? -97.746 16.799 259.590 1.00 26.93 ? 72 VAL B O 1 ATOM 4609 C CB . VAL B 1 72 ? -99.087 13.978 259.513 1.00 25.08 ? 72 VAL B CB 1 ATOM 4610 C CG1 . VAL B 1 72 ? -98.323 13.343 260.663 1.00 25.15 ? 72 VAL B CG1 1 ATOM 4611 C CG2 . VAL B 1 72 ? -100.225 13.079 259.072 1.00 26.05 ? 72 VAL B CG2 1 ATOM 4612 N N . LEU B 1 73 ? -98.416 16.453 261.718 1.00 25.87 ? 73 LEU B N 1 ATOM 4613 C CA . LEU B 1 73 ? -97.510 17.429 262.308 1.00 25.73 ? 73 LEU B CA 1 ATOM 4614 C C . LEU B 1 73 ? -96.499 16.730 263.205 1.00 28.69 ? 73 LEU B C 1 ATOM 4615 O O . LEU B 1 73 ? -96.872 16.145 264.227 1.00 25.86 ? 73 LEU B O 1 ATOM 4616 C CB . LEU B 1 73 ? -98.286 18.478 263.107 1.00 27.72 ? 73 LEU B CB 1 ATOM 4617 C CG . LEU B 1 73 ? -99.321 19.297 262.335 1.00 32.43 ? 73 LEU B CG 1 ATOM 4618 C CD1 . LEU B 1 73 ? -99.953 20.340 263.241 1.00 35.84 ? 73 LEU B CD1 1 ATOM 4619 C CD2 . LEU B 1 73 ? -98.687 19.951 261.118 1.00 40.78 ? 73 LEU B CD2 1 ATOM 4620 N N . PHE B 1 74 ? -95.227 16.794 262.821 1.00 32.42 ? 74 PHE B N 1 ATOM 4621 C CA . PHE B 1 74 ? -94.118 16.451 263.702 1.00 30.54 ? 74 PHE B CA 1 ATOM 4622 C C . PHE B 1 74 ? -93.515 17.745 264.227 1.00 31.51 ? 74 PHE B C 1 ATOM 4623 O O . PHE B 1 74 ? -93.261 18.670 263.449 1.00 43.31 ? 74 PHE B O 1 ATOM 4624 C CB . PHE B 1 74 ? -93.041 15.641 262.978 1.00 31.42 ? 74 PHE B CB 1 ATOM 4625 C CG . PHE B 1 74 ? -93.497 14.293 262.497 1.00 30.57 ? 74 PHE B CG 1 ATOM 4626 C CD1 . PHE B 1 74 ? -94.710 13.759 262.899 1.00 41.64 ? 74 PHE B CD1 1 ATOM 4627 C CD2 . PHE B 1 74 ? -92.696 13.552 261.646 1.00 29.82 ? 74 PHE B CD2 1 ATOM 4628 C CE1 . PHE B 1 74 ? -95.116 12.517 262.449 1.00 56.38 ? 74 PHE B CE1 1 ATOM 4629 C CE2 . PHE B 1 74 ? -93.095 12.312 261.198 1.00 28.84 ? 74 PHE B CE2 1 ATOM 4630 C CZ . PHE B 1 74 ? -94.306 11.794 261.599 1.00 43.51 ? 74 PHE B CZ 1 ATOM 4631 N N . ASP B 1 75 ? -93.290 17.811 265.541 1.00 29.18 ? 75 ASP B N 1 ATOM 4632 C CA . ASP B 1 75 ? -92.735 19.006 266.180 1.00 34.56 ? 75 ASP B CA 1 ATOM 4633 C C . ASP B 1 75 ? -93.571 20.246 265.877 1.00 37.64 ? 75 ASP B C 1 ATOM 4634 O O . ASP B 1 75 ? -93.041 21.358 265.808 1.00 39.42 ? 75 ASP B O 1 ATOM 4635 C CB . ASP B 1 75 ? -91.282 19.242 265.756 1.00 44.60 ? 75 ASP B CB 1 ATOM 4636 C CG . ASP B 1 75 ? -90.409 18.024 265.956 1.00 58.19 ? 75 ASP B CG 1 ATOM 4637 O OD1 . ASP B 1 75 ? -90.561 17.350 266.995 1.00 61.25 ? 75 ASP B OD1 1 ATOM 4638 O OD2 . ASP B 1 75 ? -89.575 17.738 265.071 1.00 48.12 ? 75 ASP B OD2 1 ATOM 4639 N N . GLU B 1 76 ? -94.879 20.057 265.687 1.00 36.94 ? 76 GLU B N 1 ATOM 4640 C CA . GLU B 1 76 ? -95.785 21.111 265.226 1.00 37.50 ? 76 GLU B CA 1 ATOM 4641 C C . GLU B 1 76 ? -95.379 21.647 263.854 1.00 36.69 ? 76 GLU B C 1 ATOM 4642 O O . GLU B 1 76 ? -95.565 22.829 263.560 1.00 44.61 ? 76 GLU B O 1 ATOM 4643 C CB . GLU B 1 76 ? -95.879 22.260 266.237 1.00 39.25 ? 76 GLU B CB 1 ATOM 4644 C CG . GLU B 1 76 ? -96.429 21.867 267.598 1.00 48.30 ? 76 GLU B CG 1 ATOM 4645 C CD . GLU B 1 76 ? -97.943 21.795 267.619 1.00 40.07 ? 76 GLU B CD 1 ATOM 4646 O OE1 . GLU B 1 76 ? -98.581 22.353 266.701 1.00 46.39 ? 76 GLU B OE1 1 ATOM 4647 O OE2 . GLU B 1 76 ? -98.496 21.189 268.560 1.00 39.95 ? 76 GLU B OE2 1 ATOM 4648 N N . GLN B 1 77 ? -94.825 20.785 263.000 1.00 36.94 ? 77 GLN B N 1 ATOM 4649 C CA . GLN B 1 77 ? -94.431 21.169 261.652 1.00 36.76 ? 77 GLN B CA 1 ATOM 4650 C C . GLN B 1 77 ? -94.978 20.160 260.651 1.00 34.79 ? 77 GLN B C 1 ATOM 4651 O O . GLN B 1 77 ? -95.107 18.969 260.949 1.00 35.41 ? 77 GLN B O 1 ATOM 4652 C CB . GLN B 1 77 ? -92.899 21.285 261.521 1.00 44.57 ? 77 GLN B CB 1 ATOM 4653 C CG . GLN B 1 77 ? -92.211 20.096 260.866 1.00 48.64 ? 77 GLN B CG 1 ATOM 4654 C CD . GLN B 1 77 ? -90.707 20.271 260.771 1.00 68.74 ? 77 GLN B CD 1 ATOM 4655 O OE1 . GLN B 1 77 ? -90.196 21.390 260.827 1.00 55.72 ? 77 GLN B OE1 1 ATOM 4656 N NE2 . GLN B 1 77 ? -89.990 19.162 260.629 1.00 73.38 ? 77 GLN B NE2 1 ATOM 4657 N N . GLN B 1 78 ? -95.304 20.654 259.459 1.00 34.46 ? 78 GLN B N 1 ATOM 4658 C CA . GLN B 1 78 ? -95.917 19.822 258.431 1.00 37.85 ? 78 GLN B CA 1 ATOM 4659 C C . GLN B 1 78 ? -94.926 18.785 257.917 1.00 33.51 ? 78 GLN B C 1 ATOM 4660 O O . GLN B 1 78 ? -93.778 19.112 257.601 1.00 38.27 ? 78 GLN B O 1 ATOM 4661 C CB . GLN B 1 78 ? -96.411 20.693 257.278 1.00 37.56 ? 78 GLN B CB 1 ATOM 4662 C CG . GLN B 1 78 ? -97.503 20.062 256.434 1.00 34.81 ? 78 GLN B CG 1 ATOM 4663 C CD . GLN B 1 78 ? -97.677 20.760 255.099 1.00 33.51 ? 78 GLN B CD 1 ATOM 4664 O OE1 . GLN B 1 78 ? -96.956 20.481 254.143 1.00 45.77 ? 78 GLN B OE1 1 ATOM 4665 N NE2 . GLN B 1 78 ? -98.631 21.679 255.032 1.00 36.55 ? 78 GLN B NE2 1 ATOM 4666 N N . VAL B 1 79 ? -95.370 17.530 257.832 1.00 30.45 ? 79 VAL B N 1 ATOM 4667 C CA . VAL B 1 79 ? -94.522 16.445 257.349 1.00 31.71 ? 79 VAL B CA 1 ATOM 4668 C C . VAL B 1 79 ? -95.283 15.583 256.348 1.00 36.09 ? 79 VAL B C 1 ATOM 4669 O O . VAL B 1 79 ? -94.681 14.786 255.619 1.00 52.48 ? 79 VAL B O 1 ATOM 4670 C CB . VAL B 1 79 ? -93.991 15.584 258.511 1.00 30.96 ? 79 VAL B CB 1 ATOM 4671 C CG1 . VAL B 1 79 ? -93.189 16.430 259.487 1.00 36.17 ? 79 VAL B CG1 1 ATOM 4672 C CG2 . VAL B 1 79 ? -95.138 14.884 259.222 1.00 41.35 ? 79 VAL B CG2 1 ATOM 4673 N N . TRP B 1 80 ? -96.604 15.731 256.304 1.00 32.61 ? 80 TRP B N 1 ATOM 4674 C CA . TRP B 1 80 ? -97.429 14.919 255.419 1.00 35.01 ? 80 TRP B CA 1 ATOM 4675 C C . TRP B 1 80 ? -98.760 15.623 255.208 1.00 41.17 ? 80 TRP B C 1 ATOM 4676 O O . TRP B 1 80 ? -99.233 16.352 256.084 1.00 40.38 ? 80 TRP B O 1 ATOM 4677 C CB . TRP B 1 80 ? -97.650 13.515 255.994 1.00 36.25 ? 80 TRP B CB 1 ATOM 4678 C CG . TRP B 1 80 ? -98.358 12.569 255.068 1.00 42.94 ? 80 TRP B CG 1 ATOM 4679 C CD1 . TRP B 1 80 ? -97.783 11.728 254.160 1.00 56.81 ? 80 TRP B CD1 1 ATOM 4680 C CD2 . TRP B 1 80 ? -99.773 12.360 254.966 1.00 36.77 ? 80 TRP B CD2 1 ATOM 4681 N NE1 . TRP B 1 80 ? -98.750 11.012 253.498 1.00 43.29 ? 80 TRP B NE1 1 ATOM 4682 C CE2 . TRP B 1 80 ? -99.980 11.382 253.973 1.00 39.91 ? 80 TRP B CE2 1 ATOM 4683 C CE3 . TRP B 1 80 ? -100.884 12.908 255.615 1.00 35.12 ? 80 TRP B CE3 1 ATOM 4684 C CZ2 . TRP B 1 80 ? -101.251 10.939 253.615 1.00 44.58 ? 80 TRP B CZ2 1 ATOM 4685 C CZ3 . TRP B 1 80 ? -102.145 12.467 255.258 1.00 36.55 ? 80 TRP B CZ3 1 ATOM 4686 C CH2 . TRP B 1 80 ? -102.318 11.493 254.267 1.00 39.98 ? 80 TRP B CH2 1 ATOM 4687 N N . LYS B 1 81 ? -99.359 15.400 254.039 1.00 33.67 ? 81 LYS B N 1 ATOM 4688 C CA . LYS B 1 81 ? -100.657 15.988 253.749 1.00 34.05 ? 81 LYS B CA 1 ATOM 4689 C C . LYS B 1 81 ? -101.394 15.137 252.726 1.00 35.75 ? 81 LYS B C 1 ATOM 4690 O O . LYS B 1 81 ? -100.789 14.406 251.938 1.00 40.80 ? 81 LYS B O 1 ATOM 4691 C CB . LYS B 1 81 ? -100.527 17.434 253.255 1.00 39.71 ? 81 LYS B CB 1 ATOM 4692 C CG . LYS B 1 81 ? -99.968 17.603 251.856 1.00 43.29 ? 81 LYS B CG 1 ATOM 4693 C CD . LYS B 1 81 ? -100.399 18.945 251.281 1.00 65.17 ? 81 LYS B CD 1 ATOM 4694 C CE . LYS B 1 81 ? -99.827 19.178 249.895 1.00 62.31 ? 81 LYS B CE 1 ATOM 4695 N NZ . LYS B 1 81 ? -98.353 19.381 249.941 1.00 49.30 ? 81 LYS B NZ 1 ATOM 4696 N N . GLY B 1 82 ? -102.718 15.248 252.755 1.00 37.45 ? 82 GLY B N 1 ATOM 4697 C CA . GLY B 1 82 ? -103.561 14.487 251.854 1.00 42.14 ? 82 GLY B CA 1 ATOM 4698 C C . GLY B 1 82 ? -105.017 14.662 252.235 1.00 41.10 ? 82 GLY B C 1 ATOM 4699 O O . GLY B 1 82 ? -105.366 15.576 252.982 1.00 44.18 ? 82 GLY B O 1 ATOM 4700 N N . ASP B 1 83 ? -105.856 13.774 251.713 1.00 41.91 ? 83 ASP B N 1 ATOM 4701 C CA . ASP B 1 83 ? -107.279 13.819 252.016 1.00 46.50 ? 83 ASP B CA 1 ATOM 4702 C C . ASP B 1 83 ? -107.554 13.091 253.324 1.00 48.55 ? 83 ASP B C 1 ATOM 4703 O O . ASP B 1 83 ? -106.932 12.068 253.627 1.00 55.39 ? 83 ASP B O 1 ATOM 4704 C CB . ASP B 1 83 ? -108.090 13.190 250.881 1.00 52.37 ? 83 ASP B CB 1 ATOM 4705 C CG . ASP B 1 83 ? -109.591 13.408 251.030 1.00 67.05 ? 83 ASP B CG 1 ATOM 4706 O OD1 . ASP B 1 83 ? -110.087 13.528 252.172 1.00 70.56 ? 83 ASP B OD1 1 ATOM 4707 O OD2 . ASP B 1 83 ? -110.282 13.461 249.992 1.00 93.72 ? 83 ASP B OD2 1 ATOM 4708 N N . ALA B 1 84 ? -108.491 13.629 254.104 1.00 44.19 ? 84 ALA B N 1 ATOM 4709 C CA . ALA B 1 84 ? -108.941 12.973 255.323 1.00 45.31 ? 84 ALA B CA 1 ATOM 4710 C C . ALA B 1 84 ? -109.896 11.821 255.048 1.00 43.69 ? 84 ALA B C 1 ATOM 4711 O O . ALA B 1 84 ? -110.300 11.134 255.993 1.00 44.30 ? 84 ALA B O 1 ATOM 4712 C CB . ALA B 1 84 ? -109.608 13.986 256.256 1.00 42.10 ? 84 ALA B CB 1 ATOM 4713 N N . GLU B 1 85 ? -110.271 11.605 253.784 1.00 47.66 ? 85 GLU B N 1 ATOM 4714 C CA . GLU B 1 85 ? -111.085 10.446 253.431 1.00 56.36 ? 85 GLU B CA 1 ATOM 4715 C C . GLU B 1 85 ? -110.394 9.149 253.827 1.00 58.11 ? 85 GLU B C 1 ATOM 4716 O O . GLU B 1 85 ? -111.033 8.228 254.351 1.00 69.65 ? 85 GLU B O 1 ATOM 4717 C CB . GLU B 1 85 ? -111.379 10.457 251.930 1.00 59.35 ? 85 GLU B CB 1 ATOM 4718 C CG . GLU B 1 85 ? -111.432 9.077 251.293 1.00 60.46 ? 85 GLU B CG 1 ATOM 4719 C CD . GLU B 1 85 ? -111.327 9.126 249.783 1.00 72.49 ? 85 GLU B CD 1 ATOM 4720 O OE1 . GLU B 1 85 ? -111.116 10.228 249.236 1.00 80.42 ? 85 GLU B OE1 1 ATOM 4721 O OE2 . GLU B 1 85 ? -111.448 8.060 249.143 1.00 63.81 ? 85 GLU B OE2 1 ATOM 4722 N N . SER B 1 86 ? -109.084 9.063 253.593 1.00 52.36 ? 86 SER B N 1 ATOM 4723 C CA . SER B 1 86 ? -108.357 7.834 253.887 1.00 50.43 ? 86 SER B CA 1 ATOM 4724 C C . SER B 1 86 ? -108.244 7.586 255.384 1.00 45.71 ? 86 SER B C 1 ATOM 4725 O O . SER B 1 86 ? -108.165 6.428 255.810 1.00 47.15 ? 86 SER B O 1 ATOM 4726 C CB . SER B 1 86 ? -106.967 7.886 253.254 1.00 58.30 ? 86 SER B CB 1 ATOM 4727 O OG . SER B 1 86 ? -106.242 9.013 253.717 1.00 65.33 ? 86 SER B OG 1 ATOM 4728 N N . LYS B 1 87 ? -108.238 8.650 256.193 1.00 42.43 ? 87 LYS B N 1 ATOM 4729 C CA . LYS B 1 87 ? -107.981 8.545 257.632 1.00 40.81 ? 87 LYS B CA 1 ATOM 4730 C C . LYS B 1 87 ? -106.689 7.779 257.899 1.00 45.44 ? 87 LYS B C 1 ATOM 4731 O O . LYS B 1 87 ? -106.556 7.080 258.906 1.00 51.52 ? 87 LYS B O 1 ATOM 4732 C CB . LYS B 1 87 ? -109.158 7.894 258.364 1.00 41.35 ? 87 LYS B CB 1 ATOM 4733 C CG . LYS B 1 87 ? -110.482 8.622 258.198 1.00 43.34 ? 87 LYS B CG 1 ATOM 4734 C CD . LYS B 1 87 ? -111.592 7.918 258.965 1.00 48.99 ? 87 LYS B CD 1 ATOM 4735 C CE . LYS B 1 87 ? -112.914 8.655 258.831 1.00 58.21 ? 87 LYS B CE 1 ATOM 4736 N NZ . LYS B 1 87 ? -113.996 8.013 259.629 1.00 57.49 ? 87 LYS B NZ 1 ATOM 4737 N N . ARG B 1 88 ? -105.729 7.912 256.987 1.00 41.62 ? 88 ARG B N 1 ATOM 4738 C CA . ARG B 1 88 ? -104.507 7.125 256.993 1.00 40.18 ? 88 ARG B CA 1 ATOM 4739 C C . ARG B 1 88 ? -103.348 8.004 256.552 1.00 39.13 ? 88 ARG B C 1 ATOM 4740 O O . ARG B 1 88 ? -103.511 8.867 255.685 1.00 56.26 ? 88 ARG B O 1 ATOM 4741 C CB . ARG B 1 88 ? -104.632 5.911 256.061 1.00 48.64 ? 88 ARG B CB 1 ATOM 4742 C CG . ARG B 1 88 ? -103.372 5.072 255.932 1.00 54.97 ? 88 ARG B CG 1 ATOM 4743 C CD . ARG B 1 88 ? -103.558 3.957 254.916 1.00 87.49 ? 88 ARG B CD 1 ATOM 4744 N NE . ARG B 1 88 ? -103.757 4.478 253.566 1.00 82.54 ? 88 ARG B NE 1 ATOM 4745 C CZ . ARG B 1 88 ? -102.774 4.739 252.711 1.00 73.03 ? 88 ARG B CZ 1 ATOM 4746 N NH1 . ARG B 1 88 ? -101.512 4.531 253.063 1.00 76.36 ? 88 ARG B NH1 1 ATOM 4747 N NH2 . ARG B 1 88 ? -103.050 5.210 251.503 1.00 64.96 ? 88 ARG B NH2 1 ATOM 4748 N N . ALA B 1 89 ? -102.182 7.783 257.152 1.00 35.83 ? 89 ALA B N 1 ATOM 4749 C CA . ALA B 1 89 ? -100.989 8.526 256.782 1.00 32.63 ? 89 ALA B CA 1 ATOM 4750 C C . ALA B 1 89 ? -99.764 7.664 257.039 1.00 30.46 ? 89 ALA B C 1 ATOM 4751 O O . ALA B 1 89 ? -99.674 6.989 258.068 1.00 29.76 ? 89 ALA B O 1 ATOM 4752 C CB . ALA B 1 89 ? -100.886 9.843 257.558 1.00 35.48 ? 89 ALA B CB 1 ATOM 4753 N N . THR B 1 90 ? -98.828 7.689 256.092 1.00 29.12 ? 90 THR B N 1 ATOM 4754 C CA . THR B 1 90 ? -97.566 6.968 256.205 1.00 25.87 ? 90 THR B CA 1 ATOM 4755 C C . THR B 1 90 ? -96.435 7.956 255.972 1.00 28.75 ? 90 THR B C 1 ATOM 4756 O O . THR B 1 90 ? -96.311 8.510 254.875 1.00 28.28 ? 90 THR B O 1 ATOM 4757 C CB . THR B 1 90 ? -97.491 5.816 255.200 1.00 27.51 ? 90 THR B CB 1 ATOM 4758 O OG1 . THR B 1 90 ? -98.648 4.982 255.338 1.00 37.34 ? 90 THR B OG1 1 ATOM 4759 C CG2 . THR B 1 90 ? -96.242 4.983 255.441 1.00 34.16 ? 90 THR B CG2 1 ATOM 4760 N N . ILE B 1 91 ? -95.617 8.177 256.997 1.00 29.53 ? 91 ILE B N 1 ATOM 4761 C CA . ILE B 1 91 ? -94.535 9.154 256.950 1.00 27.08 ? 91 ILE B CA 1 ATOM 4762 C C . ILE B 1 91 ? -93.209 8.414 257.034 1.00 29.14 ? 91 ILE B C 1 ATOM 4763 O O . ILE B 1 91 ? -93.025 7.551 257.901 1.00 27.38 ? 91 ILE B O 1 ATOM 4764 C CB . ILE B 1 91 ? -94.655 10.193 258.078 1.00 27.88 ? 91 ILE B CB 1 ATOM 4765 C CG1 . ILE B 1 91 ? -96.033 10.858 258.059 1.00 28.90 ? 91 ILE B CG1 1 ATOM 4766 C CG2 . ILE B 1 91 ? -93.568 11.244 257.941 1.00 31.73 ? 91 ILE B CG2 1 ATOM 4767 C CD1 . ILE B 1 91 ? -97.032 10.241 259.017 1.00 29.01 ? 91 ILE B CD1 1 ATOM 4768 N N . LYS B 1 92 ? -92.289 8.756 256.138 1.00 29.46 ? 92 LYS B N 1 ATOM 4769 C CA . LYS B 1 92 ? -90.967 8.146 256.096 1.00 26.31 ? 92 LYS B CA 1 ATOM 4770 C C . LYS B 1 92 ? -90.025 8.918 257.013 1.00 25.22 ? 92 LYS B C 1 ATOM 4771 O O . LYS B 1 92 ? -89.862 10.133 256.861 1.00 34.92 ? 92 LYS B O 1 ATOM 4772 C CB . LYS B 1 92 ? -90.436 8.132 254.664 1.00 25.95 ? 92 LYS B CB 1 ATOM 4773 C CG . LYS B 1 92 ? -89.029 7.590 254.521 1.00 30.14 ? 92 LYS B CG 1 ATOM 4774 C CD . LYS B 1 92 ? -88.579 7.622 253.070 1.00 34.58 ? 92 LYS B CD 1 ATOM 4775 C CE . LYS B 1 92 ? -88.376 9.049 252.588 1.00 29.84 ? 92 LYS B CE 1 ATOM 4776 N NZ . LYS B 1 92 ? -87.905 9.096 251.177 1.00 29.65 ? 92 LYS B NZ 1 ATOM 4777 N N . VAL B 1 93 ? -89.409 8.214 257.959 1.00 24.78 ? 93 VAL B N 1 ATOM 4778 C CA . VAL B 1 93 ? -88.476 8.805 258.910 1.00 25.15 ? 93 VAL B CA 1 ATOM 4779 C C . VAL B 1 93 ? -87.116 8.150 258.714 1.00 30.98 ? 93 VAL B C 1 ATOM 4780 O O . VAL B 1 93 ? -87.023 6.920 258.619 1.00 42.22 ? 93 VAL B O 1 ATOM 4781 C CB . VAL B 1 93 ? -88.964 8.642 260.362 1.00 24.24 ? 93 VAL B CB 1 ATOM 4782 C CG1 . VAL B 1 93 ? -87.908 9.130 261.340 1.00 24.51 ? 93 VAL B CG1 1 ATOM 4783 C CG2 . VAL B 1 93 ? -90.268 9.395 260.564 1.00 26.51 ? 93 VAL B CG2 1 ATOM 4784 N N . LEU B 1 94 ? -86.067 8.970 258.652 1.00 25.17 ? 94 LEU B N 1 ATOM 4785 C CA . LEU B 1 94 ? -84.717 8.490 258.388 1.00 22.70 ? 94 LEU B CA 1 ATOM 4786 C C . LEU B 1 94 ? -83.797 8.532 259.597 1.00 23.68 ? 94 LEU B C 1 ATOM 4787 O O . LEU B 1 94 ? -82.842 7.756 259.651 1.00 24.43 ? 94 LEU B O 1 ATOM 4788 C CB . LEU B 1 94 ? -84.074 9.306 257.258 1.00 24.95 ? 94 LEU B CB 1 ATOM 4789 C CG . LEU B 1 94 ? -84.239 8.834 255.810 1.00 30.23 ? 94 LEU B CG 1 ATOM 4790 C CD1 . LEU B 1 94 ? -85.693 8.548 255.476 1.00 26.71 ? 94 LEU B CD1 1 ATOM 4791 C CD2 . LEU B 1 94 ? -83.662 9.862 254.846 1.00 23.80 ? 94 LEU B CD2 1 ATOM 4792 N N . VAL B 1 95 ? -84.050 9.415 260.560 1.00 28.79 ? 95 VAL B N 1 ATOM 4793 C CA . VAL B 1 95 ? -83.149 9.622 261.686 1.00 23.36 ? 95 VAL B CA 1 ATOM 4794 C C . VAL B 1 95 ? -83.874 9.278 262.980 1.00 23.21 ? 95 VAL B C 1 ATOM 4795 O O . VAL B 1 95 ? -85.080 9.502 263.118 1.00 23.93 ? 95 VAL B O 1 ATOM 4796 C CB . VAL B 1 95 ? -82.615 11.071 261.728 1.00 28.41 ? 95 VAL B CB 1 ATOM 4797 C CG1 . VAL B 1 95 ? -81.464 11.193 262.717 1.00 29.56 ? 95 VAL B CG1 1 ATOM 4798 C CG2 . VAL B 1 95 ? -82.184 11.519 260.340 1.00 56.52 ? 95 VAL B CG2 1 ATOM 4799 N N . SER B 1 96 ? -83.123 8.729 263.932 1.00 23.87 ? 96 SER B N 1 ATOM 4800 C CA . SER B 1 96 ? -83.676 8.402 265.236 1.00 21.67 ? 96 SER B CA 1 ATOM 4801 C C . SER B 1 96 ? -84.043 9.671 266.000 1.00 25.59 ? 96 SER B C 1 ATOM 4802 O O . SER B 1 96 ? -83.550 10.767 265.717 1.00 32.42 ? 96 SER B O 1 ATOM 4803 C CB . SER B 1 96 ? -82.680 7.575 266.049 1.00 19.15 ? 96 SER B CB 1 ATOM 4804 O OG . SER B 1 96 ? -81.414 8.209 266.096 1.00 17.17 ? 96 SER B OG 1 ATOM 4805 N N . GLY B 1 97 ? -84.923 9.510 266.985 1.00 25.09 ? 97 GLY B N 1 ATOM 4806 C CA . GLY B 1 97 ? -85.350 10.626 267.806 1.00 24.32 ? 97 GLY B CA 1 ATOM 4807 C C . GLY B 1 97 ? -86.810 10.561 268.203 1.00 24.86 ? 97 GLY B C 1 ATOM 4808 O O . GLY B 1 97 ? -87.576 9.762 267.658 1.00 22.69 ? 97 GLY B O 1 ATOM 4809 N N . GLN B 1 98 ? -87.205 11.401 269.154 1.00 25.48 ? 98 GLN B N 1 ATOM 4810 C CA . GLN B 1 98 ? -88.578 11.469 269.628 1.00 26.11 ? 98 GLN B CA 1 ATOM 4811 C C . GLN B 1 98 ? -89.226 12.768 269.167 1.00 26.55 ? 98 GLN B C 1 ATOM 4812 O O . GLN B 1 98 ? -88.552 13.786 268.983 1.00 25.69 ? 98 GLN B O 1 ATOM 4813 C CB . GLN B 1 98 ? -88.638 11.371 271.154 1.00 27.94 ? 98 GLN B CB 1 ATOM 4814 C CG . GLN B 1 98 ? -88.119 10.061 271.715 1.00 40.21 ? 98 GLN B CG 1 ATOM 4815 C CD . GLN B 1 98 ? -88.195 10.009 273.227 1.00 54.31 ? 98 GLN B CD 1 ATOM 4816 O OE1 . GLN B 1 98 ? -88.285 11.042 273.891 1.00 33.36 ? 98 GLN B OE1 1 ATOM 4817 N NE2 . GLN B 1 98 ? -88.159 8.803 273.781 1.00 67.50 ? 98 GLN B NE2 1 ATOM 4818 N N . PHE B 1 99 ? -90.544 12.723 268.985 1.00 26.44 ? 99 PHE B N 1 ATOM 4819 C CA . PHE B 1 99 ? -91.293 13.895 268.553 1.00 23.28 ? 99 PHE B CA 1 ATOM 4820 C C . PHE B 1 99 ? -92.775 13.658 268.800 1.00 23.38 ? 99 PHE B C 1 ATOM 4821 O O . PHE B 1 99 ? -93.235 12.517 268.892 1.00 24.55 ? 99 PHE B O 1 ATOM 4822 C CB . PHE B 1 99 ? -91.034 14.218 267.076 1.00 24.60 ? 99 PHE B CB 1 ATOM 4823 C CG . PHE B 1 99 ? -91.164 13.034 266.161 1.00 23.75 ? 99 PHE B CG 1 ATOM 4824 C CD1 . PHE B 1 99 ? -92.395 12.675 265.638 1.00 25.40 ? 99 PHE B CD1 1 ATOM 4825 C CD2 . PHE B 1 99 ? -90.052 12.282 265.822 1.00 25.17 ? 99 PHE B CD2 1 ATOM 4826 C CE1 . PHE B 1 99 ? -92.515 11.588 264.795 1.00 26.19 ? 99 PHE B CE1 1 ATOM 4827 C CE2 . PHE B 1 99 ? -90.166 11.193 264.981 1.00 41.06 ? 99 PHE B CE2 1 ATOM 4828 C CZ . PHE B 1 99 ? -91.399 10.846 264.467 1.00 29.77 ? 99 PHE B CZ 1 ATOM 4829 N N . ASN B 1 100 ? -93.516 14.759 268.907 1.00 25.10 ? 100 ASN B N 1 ATOM 4830 C CA . ASN B 1 100 ? -94.960 14.710 269.089 1.00 21.84 ? 100 ASN B CA 1 ATOM 4831 C C . ASN B 1 100 ? -95.646 14.749 267.730 1.00 22.35 ? 100 ASN B C 1 ATOM 4832 O O . ASN B 1 100 ? -95.366 15.630 266.911 1.00 34.58 ? 100 ASN B O 1 ATOM 4833 C CB . ASN B 1 100 ? -95.439 15.875 269.956 1.00 18.61 ? 100 ASN B CB 1 ATOM 4834 C CG . ASN B 1 100 ? -94.803 15.878 271.331 1.00 20.92 ? 100 ASN B CG 1 ATOM 4835 O OD1 . ASN B 1 100 ? -94.462 14.827 271.872 1.00 28.33 ? 100 ASN B OD1 1 ATOM 4836 N ND2 . ASN B 1 100 ? -94.641 17.064 271.905 1.00 16.08 ? 100 ASN B ND2 1 ATOM 4837 N N . MET B 1 101 ? -96.542 13.795 267.495 1.00 21.57 ? 101 MET B N 1 ATOM 4838 C CA . MET B 1 101 ? -97.259 13.681 266.233 1.00 20.46 ? 101 MET B CA 1 ATOM 4839 C C . MET B 1 101 ? -98.712 14.089 266.429 1.00 21.51 ? 101 MET B C 1 ATOM 4840 O O . MET B 1 101 ? -99.364 13.643 267.379 1.00 22.02 ? 101 MET B O 1 ATOM 4841 C CB . MET B 1 101 ? -97.178 12.257 265.683 1.00 18.77 ? 101 MET B CB 1 ATOM 4842 C CG . MET B 1 101 ? -97.935 12.058 264.384 1.00 18.00 ? 101 MET B CG 1 ATOM 4843 S SD . MET B 1 101 ? -97.766 10.383 263.750 1.00 5.00 ? 101 MET B SD 1 ATOM 4844 C CE . MET B 1 101 ? -98.345 9.435 265.154 1.00 18.67 ? 101 MET B CE 1 ATOM 4845 N N . ARG B 1 102 ? -99.213 14.934 265.530 1.00 22.41 ? 102 ARG B N 1 ATOM 4846 C CA . ARG B 1 102 ? -100.577 15.434 265.605 1.00 23.51 ? 102 ARG B CA 1 ATOM 4847 C C . ARG B 1 102 ? -101.194 15.412 264.215 1.00 26.12 ? 102 ARG B C 1 ATOM 4848 O O . ARG B 1 102 ? -100.502 15.587 263.209 1.00 25.04 ? 102 ARG B O 1 ATOM 4849 C CB . ARG B 1 102 ? -100.624 16.859 266.180 1.00 27.02 ? 102 ARG B CB 1 ATOM 4850 C CG . ARG B 1 102 ? -100.034 16.973 267.575 1.00 29.01 ? 102 ARG B CG 1 ATOM 4851 C CD . ARG B 1 102 ? -99.947 18.412 268.056 1.00 35.50 ? 102 ARG B CD 1 ATOM 4852 N NE . ARG B 1 102 ? -101.258 19.014 268.282 1.00 52.43 ? 102 ARG B NE 1 ATOM 4853 C CZ . ARG B 1 102 ? -101.501 19.940 269.205 1.00 47.54 ? 102 ARG B CZ 1 ATOM 4854 N NH1 . ARG B 1 102 ? -100.520 20.369 269.987 1.00 57.49 ? 102 ARG B NH1 1 ATOM 4855 N NH2 . ARG B 1 102 ? -102.722 20.437 269.350 1.00 41.67 ? 102 ARG B NH2 1 ATOM 4856 N N . VAL B 1 103 ? -102.505 15.192 264.169 1.00 28.50 ? 103 VAL B N 1 ATOM 4857 C CA . VAL B 1 103 ? -103.265 15.197 262.924 1.00 25.29 ? 103 VAL B CA 1 ATOM 4858 C C . VAL B 1 103 ? -104.002 16.523 262.811 1.00 25.45 ? 103 VAL B C 1 ATOM 4859 O O . VAL B 1 103 ? -104.586 17.010 263.787 1.00 28.97 ? 103 VAL B O 1 ATOM 4860 C CB . VAL B 1 103 ? -104.242 14.007 262.860 1.00 26.22 ? 103 VAL B CB 1 ATOM 4861 C CG1 . VAL B 1 103 ? -105.043 14.042 261.567 1.00 30.53 ? 103 VAL B CG1 1 ATOM 4862 C CG2 . VAL B 1 103 ? -103.483 12.698 262.976 1.00 31.34 ? 103 VAL B CG2 1 ATOM 4863 N N . LYS B 1 104 ? -103.972 17.110 261.617 1.00 26.94 ? 104 LYS B N 1 ATOM 4864 C CA . LYS B 1 104 ? -104.529 18.435 261.363 1.00 30.39 ? 104 LYS B CA 1 ATOM 4865 C C . LYS B 1 104 ? -105.621 18.313 260.309 1.00 32.07 ? 104 LYS B C 1 ATOM 4866 O O . LYS B 1 104 ? -105.334 18.030 259.142 1.00 33.97 ? 104 LYS B O 1 ATOM 4867 C CB . LYS B 1 104 ? -103.432 19.397 260.910 1.00 46.91 ? 104 LYS B CB 1 ATOM 4868 C CG . LYS B 1 104 ? -103.883 20.827 260.667 1.00 45.17 ? 104 LYS B CG 1 ATOM 4869 C CD . LYS B 1 104 ? -104.190 21.542 261.968 1.00 68.58 ? 104 LYS B CD 1 ATOM 4870 C CE . LYS B 1 104 ? -103.796 23.009 261.892 1.00 63.42 ? 104 LYS B CE 1 ATOM 4871 N NZ . LYS B 1 104 ? -104.309 23.668 260.660 1.00 66.59 ? 104 LYS B NZ 1 ATOM 4872 N N . LEU B 1 105 ? -106.869 18.525 260.718 1.00 34.93 ? 105 LEU B N 1 ATOM 4873 C CA . LEU B 1 105 ? -108.008 18.527 259.809 1.00 36.34 ? 105 LEU B CA 1 ATOM 4874 C C . LEU B 1 105 ? -108.400 19.965 259.505 1.00 35.33 ? 105 LEU B C 1 ATOM 4875 O O . LEU B 1 105 ? -108.611 20.759 260.427 1.00 35.73 ? 105 LEU B O 1 ATOM 4876 C CB . LEU B 1 105 ? -109.196 17.779 260.414 1.00 37.49 ? 105 LEU B CB 1 ATOM 4877 C CG . LEU B 1 105 ? -108.980 16.329 260.846 1.00 37.13 ? 105 LEU B CG 1 ATOM 4878 C CD1 . LEU B 1 105 ? -110.277 15.744 261.382 1.00 41.25 ? 105 LEU B CD1 1 ATOM 4879 C CD2 . LEU B 1 105 ? -108.449 15.496 259.692 1.00 64.09 ? 105 LEU B CD2 1 ATOM 4880 N N . CYS B 1 106 ? -108.506 20.296 258.220 1.00 32.82 ? 106 CYS B N 1 ATOM 4881 C CA . CYS B 1 106 ? -108.818 21.652 257.791 1.00 35.39 ? 106 CYS B CA 1 ATOM 4882 C C . CYS B 1 106 ? -110.028 21.651 256.868 1.00 36.83 ? 106 CYS B C 1 ATOM 4883 O O . CYS B 1 106 ? -110.267 20.695 256.126 1.00 39.61 ? 106 CYS B O 1 ATOM 4884 C CB . CYS B 1 106 ? -107.629 22.304 257.074 1.00 32.64 ? 106 CYS B CB 1 ATOM 4885 S SG . CYS B 1 106 ? -106.332 22.938 258.162 1.00 41.76 ? 106 CYS B SG 1 ATOM 4886 N N . ASN B 1 107 ? -110.788 22.746 256.921 1.00 38.67 ? 107 ASN B N 1 ATOM 4887 C CA . ASN B 1 107 ? -111.954 22.945 256.073 1.00 39.59 ? 107 ASN B CA 1 ATOM 4888 C C . ASN B 1 107 ? -111.933 24.379 255.556 1.00 38.72 ? 107 ASN B C 1 ATOM 4889 O O . ASN B 1 107 ? -110.990 25.136 255.806 1.00 42.95 ? 107 ASN B O 1 ATOM 4890 C CB . ASN B 1 107 ? -113.250 22.636 256.833 1.00 42.42 ? 107 ASN B CB 1 ATOM 4891 C CG . ASN B 1 107 ? -114.405 22.294 255.910 1.00 53.87 ? 107 ASN B CG 1 ATOM 4892 O OD1 . ASN B 1 107 ? -114.456 22.748 254.767 1.00 63.11 ? 107 ASN B OD1 1 ATOM 4893 N ND2 . ASN B 1 107 ? -115.338 21.488 256.402 1.00 48.51 ? 107 ASN B ND2 1 ATOM 4894 N N . GLU B 1 108 ? -112.987 24.753 254.827 1.00 38.60 ? 108 GLU B N 1 ATOM 4895 C CA . GLU B 1 108 ? -113.055 26.093 254.252 1.00 38.00 ? 108 GLU B CA 1 ATOM 4896 C C . GLU B 1 108 ? -113.084 27.161 255.339 1.00 38.50 ? 108 GLU B C 1 ATOM 4897 O O . GLU B 1 108 ? -112.487 28.233 255.182 1.00 37.26 ? 108 GLU B O 1 ATOM 4898 C CB . GLU B 1 108 ? -114.281 26.207 253.342 1.00 47.37 ? 108 GLU B CB 1 ATOM 4899 C CG . GLU B 1 108 ? -114.383 27.510 252.553 1.00 41.29 ? 108 GLU B CG 1 ATOM 4900 C CD . GLU B 1 108 ? -115.007 28.640 253.351 1.00 49.67 ? 108 GLU B CD 1 ATOM 4901 O OE1 . GLU B 1 108 ? -115.955 28.374 254.120 1.00 40.14 ? 108 GLU B OE1 1 ATOM 4902 O OE2 . GLU B 1 108 ? -114.549 29.794 253.212 1.00 59.01 ? 108 GLU B OE2 1 ATOM 4903 N N . ASP B 1 109 ? -113.771 26.890 256.447 1.00 43.40 ? 109 ASP B N 1 ATOM 4904 C CA . ASP B 1 109 ? -113.840 27.844 257.547 1.00 47.16 ? 109 ASP B CA 1 ATOM 4905 C C . ASP B 1 109 ? -112.523 27.858 258.313 1.00 49.49 ? 109 ASP B C 1 ATOM 4906 O O . ASP B 1 109 ? -111.750 28.817 258.214 1.00 63.53 ? 109 ASP B O 1 ATOM 4907 C CB . ASP B 1 109 ? -115.003 27.504 258.484 1.00 52.61 ? 109 ASP B CB 1 ATOM 4908 C CG . ASP B 1 109 ? -115.392 28.666 259.384 1.00 59.30 ? 109 ASP B CG 1 ATOM 4909 O OD1 . ASP B 1 109 ? -114.522 29.504 259.702 1.00 119.37 ? 109 ASP B OD1 1 ATOM 4910 O OD2 . ASP B 1 109 ? -116.574 28.739 259.779 1.00 49.81 ? 109 ASP B OD2 1 ATOM 4911 N N . GLY B 1 110 ? -112.262 26.802 259.077 1.00 50.31 ? 110 GLY B N 1 ATOM 4912 C CA . GLY B 1 110 ? -111.045 26.717 259.859 1.00 61.67 ? 110 GLY B CA 1 ATOM 4913 C C . GLY B 1 110 ? -110.499 25.308 259.955 1.00 49.83 ? 110 GLY B C 1 ATOM 4914 O O . GLY B 1 110 ? -110.803 24.459 259.112 1.00 72.57 ? 110 GLY B O 1 ATOM 4915 N N . CYS B 1 111 ? -109.694 25.044 260.982 1.00 36.13 ? 111 CYS B N 1 ATOM 4916 C CA . CYS B 1 111 ? -109.076 23.742 261.168 1.00 34.95 ? 111 CYS B CA 1 ATOM 4917 C C . CYS B 1 111 ? -109.225 23.291 262.613 1.00 33.29 ? 111 CYS B C 1 ATOM 4918 O O . CYS B 1 111 ? -109.342 24.109 263.529 1.00 39.50 ? 111 CYS B O 1 ATOM 4919 C CB . CYS B 1 111 ? -107.590 23.766 260.789 1.00 35.42 ? 111 CYS B CB 1 ATOM 4920 S SG . CYS B 1 111 ? -107.227 24.463 259.161 1.00 34.02 ? 111 CYS B SG 1 ATOM 4921 N N . SER B 1 112 ? -109.218 21.974 262.806 1.00 33.95 ? 112 SER B N 1 ATOM 4922 C CA . SER B 1 112 ? -109.251 21.359 264.126 1.00 33.91 ? 112 SER B CA 1 ATOM 4923 C C . SER B 1 112 ? -108.026 20.472 264.291 1.00 38.43 ? 112 SER B C 1 ATOM 4924 O O . SER B 1 112 ? -107.611 19.790 263.348 1.00 38.61 ? 112 SER B O 1 ATOM 4925 C CB . SER B 1 112 ? -110.528 20.539 264.329 1.00 38.04 ? 112 SER B CB 1 ATOM 4926 O OG . SER B 1 112 ? -110.588 19.457 263.417 1.00 39.69 ? 112 SER B OG 1 ATOM 4927 N N . VAL B 1 113 ? -107.449 20.481 265.490 1.00 37.64 ? 113 VAL B N 1 ATOM 4928 C CA . VAL B 1 113 ? -106.189 19.802 265.763 1.00 36.87 ? 113 VAL B CA 1 ATOM 4929 C C . VAL B 1 113 ? -106.431 18.698 266.782 1.00 43.40 ? 113 VAL B C 1 ATOM 4930 O O . VAL B 1 113 ? -107.203 18.874 267.732 1.00 52.38 ? 113 VAL B O 1 ATOM 4931 C CB . VAL B 1 113 ? -105.114 20.785 266.271 1.00 44.61 ? 113 VAL B CB 1 ATOM 4932 C CG1 . VAL B 1 113 ? -103.742 20.130 266.251 1.00 68.20 ? 113 VAL B CG1 1 ATOM 4933 C CG2 . VAL B 1 113 ? -105.122 22.060 265.441 1.00 57.93 ? 113 VAL B CG2 1 ATOM 4934 N N . SER B 1 114 ? -105.763 17.564 266.585 1.00 36.63 ? 114 SER B N 1 ATOM 4935 C CA . SER B 1 114 ? -105.901 16.420 267.472 1.00 32.63 ? 114 SER B CA 1 ATOM 4936 C C . SER B 1 114 ? -104.973 16.558 268.676 1.00 30.95 ? 114 SER B C 1 ATOM 4937 O O . SER B 1 114 ? -104.173 17.492 268.783 1.00 34.17 ? 114 SER B O 1 ATOM 4938 C CB . SER B 1 114 ? -105.613 15.127 266.714 1.00 34.07 ? 114 SER B CB 1 ATOM 4939 O OG . SER B 1 114 ? -104.261 15.074 266.297 1.00 30.55 ? 114 SER B OG 1 ATOM 4940 N N . ASP B 1 115 ? -105.083 15.605 269.603 1.00 31.80 ? 115 ASP B N 1 ATOM 4941 C CA . ASP B 1 115 ? -104.189 15.561 270.747 1.00 29.54 ? 115 ASP B CA 1 ATOM 4942 C C . ASP B 1 115 ? -102.843 14.963 270.344 1.00 36.43 ? 115 ASP B C 1 ATOM 4943 O O . ASP B 1 115 ? -102.781 14.068 269.497 1.00 29.15 ? 115 ASP B O 1 ATOM 4944 C CB . ASP B 1 115 ? -104.803 14.740 271.876 1.00 23.87 ? 115 ASP B CB 1 ATOM 4945 C CG . ASP B 1 115 ? -105.835 15.518 272.667 1.00 23.01 ? 115 ASP B CG 1 ATOM 4946 O OD1 . ASP B 1 115 ? -105.740 16.762 272.704 1.00 23.55 ? 115 ASP B OD1 1 ATOM 4947 O OD2 . ASP B 1 115 ? -106.741 14.886 273.249 1.00 30.01 ? 115 ASP B OD2 1 ATOM 4948 N N . PRO B 1 116 ? -101.749 15.442 270.934 1.00 24.98 ? 116 PRO B N 1 ATOM 4949 C CA . PRO B 1 116 ? -100.425 14.951 270.537 1.00 23.13 ? 116 PRO B CA 1 ATOM 4950 C C . PRO B 1 116 ? -100.089 13.611 271.174 1.00 21.59 ? 116 PRO B C 1 ATOM 4951 O O . PRO B 1 116 ? -100.404 13.352 272.338 1.00 21.06 ? 116 PRO B O 1 ATOM 4952 C CB . PRO B 1 116 ? -99.483 16.051 271.040 1.00 23.61 ? 116 PRO B CB 1 ATOM 4953 C CG . PRO B 1 116 ? -100.182 16.603 272.233 1.00 22.77 ? 116 PRO B CG 1 ATOM 4954 C CD . PRO B 1 116 ? -101.659 16.535 271.920 1.00 28.73 ? 116 PRO B CD 1 ATOM 4955 N N . VAL B 1 117 ? -99.435 12.757 270.390 1.00 20.59 ? 117 VAL B N 1 ATOM 4956 C CA . VAL B 1 117 ? -98.916 11.482 270.867 1.00 19.12 ? 117 VAL B CA 1 ATOM 4957 C C . VAL B 1 117 ? -97.411 11.471 270.648 1.00 22.21 ? 117 VAL B C 1 ATOM 4958 O O . VAL B 1 117 ? -96.887 12.158 269.765 1.00 27.92 ? 117 VAL B O 1 ATOM 4959 C CB . VAL B 1 117 ? -99.579 10.277 270.167 1.00 20.51 ? 117 VAL B CB 1 ATOM 4960 C CG1 . VAL B 1 117 ? -101.074 10.266 270.436 1.00 26.88 ? 117 VAL B CG1 1 ATOM 4961 C CG2 . VAL B 1 117 ? -99.299 10.311 268.674 1.00 22.55 ? 117 VAL B CG2 1 ATOM 4962 N N . LEU B 1 118 ? -96.713 10.686 271.463 1.00 24.96 ? 118 LEU B N 1 ATOM 4963 C CA . LEU B 1 118 ? -95.257 10.634 271.430 1.00 23.12 ? 118 LEU B CA 1 ATOM 4964 C C . LEU B 1 118 ? -94.809 9.479 270.542 1.00 23.15 ? 118 LEU B C 1 ATOM 4965 O O . LEU B 1 118 ? -95.159 8.321 270.795 1.00 23.19 ? 118 LEU B O 1 ATOM 4966 C CB . LEU B 1 118 ? -94.691 10.478 272.840 1.00 25.45 ? 118 LEU B CB 1 ATOM 4967 C CG . LEU B 1 118 ? -93.210 10.110 272.949 1.00 24.67 ? 118 LEU B CG 1 ATOM 4968 C CD1 . LEU B 1 118 ? -92.339 11.145 272.253 1.00 37.57 ? 118 LEU B CD1 1 ATOM 4969 C CD2 . LEU B 1 118 ? -92.806 9.955 274.409 1.00 23.42 ? 118 LEU B CD2 1 ATOM 4970 N N . VAL B 1 119 ? -94.039 9.798 269.504 1.00 23.93 ? 119 VAL B N 1 ATOM 4971 C CA . VAL B 1 119 ? -93.464 8.804 268.606 1.00 22.98 ? 119 VAL B CA 1 ATOM 4972 C C . VAL B 1 119 ? -91.983 8.669 268.923 1.00 26.64 ? 119 VAL B C 1 ATOM 4973 O O . VAL B 1 119 ? -91.297 9.666 269.180 1.00 40.52 ? 119 VAL B O 1 ATOM 4974 C CB . VAL B 1 119 ? -93.679 9.192 267.131 1.00 20.02 ? 119 VAL B CB 1 ATOM 4975 C CG1 . VAL B 1 119 ? -93.171 8.094 266.206 1.00 22.03 ? 119 VAL B CG1 1 ATOM 4976 C CG2 . VAL B 1 119 ? -95.144 9.476 266.870 1.00 35.53 ? 119 VAL B CG2 1 ATOM 4977 N N . LYS B 1 120 ? -91.487 7.434 268.914 1.00 27.19 ? 120 LYS B N 1 ATOM 4978 C CA . LYS B 1 120 ? -90.080 7.151 269.167 1.00 25.25 ? 120 LYS B CA 1 ATOM 4979 C C . LYS B 1 120 ? -89.512 6.380 267.986 1.00 23.36 ? 120 LYS B C 1 ATOM 4980 O O . LYS B 1 120 ? -90.028 5.316 267.628 1.00 32.05 ? 120 LYS B O 1 ATOM 4981 C CB . LYS B 1 120 ? -89.899 6.358 270.463 1.00 29.29 ? 120 LYS B CB 1 ATOM 4982 C CG . LYS B 1 120 ? -90.714 6.882 271.628 1.00 31.46 ? 120 LYS B CG 1 ATOM 4983 C CD . LYS B 1 120 ? -90.373 6.144 272.908 1.00 50.63 ? 120 LYS B CD 1 ATOM 4984 C CE . LYS B 1 120 ? -91.476 6.300 273.936 1.00 48.55 ? 120 LYS B CE 1 ATOM 4985 N NZ . LYS B 1 120 ? -92.739 5.644 273.494 1.00 37.63 ? 120 LYS B NZ 1 ATOM 4986 N N . VAL B 1 121 ? -88.458 6.920 267.382 1.00 21.11 ? 121 VAL B N 1 ATOM 4987 C CA . VAL B 1 121 ? -87.721 6.254 266.316 1.00 19.92 ? 121 VAL B CA 1 ATOM 4988 C C . VAL B 1 121 ? -86.349 5.897 266.867 1.00 22.98 ? 121 VAL B C 1 ATOM 4989 O O . VAL B 1 121 ? -85.623 6.772 267.357 1.00 24.61 ? 121 VAL B O 1 ATOM 4990 C CB . VAL B 1 121 ? -87.608 7.135 265.064 1.00 21.30 ? 121 VAL B CB 1 ATOM 4991 C CG1 . VAL B 1 121 ? -86.875 6.392 263.961 1.00 34.29 ? 121 VAL B CG1 1 ATOM 4992 C CG2 . VAL B 1 121 ? -88.989 7.564 264.596 1.00 22.50 ? 121 VAL B CG2 1 ATOM 4993 N N . ALA B 1 122 ? -85.996 4.619 266.796 1.00 22.94 ? 122 ALA B N 1 ATOM 4994 C CA . ALA B 1 122 ? -84.789 4.108 267.421 1.00 20.90 ? 122 ALA B CA 1 ATOM 4995 C C . ALA B 1 122 ? -83.726 3.784 266.381 1.00 21.33 ? 122 ALA B C 1 ATOM 4996 O O . ALA B 1 122 ? -84.032 3.433 265.238 1.00 29.58 ? 122 ALA B O 1 ATOM 4997 C CB . ALA B 1 122 ? -85.088 2.859 268.250 1.00 18.88 ? 122 ALA B CB 1 ATOM 4998 N N . ASP B 1 123 ? -82.469 3.904 266.799 1.00 21.14 ? 123 ASP B N 1 ATOM 4999 C CA . ASP B 1 123 ? -81.332 3.525 265.974 1.00 21.19 ? 123 ASP B CA 1 ATOM 5000 C C . ASP B 1 123 ? -80.155 3.249 266.895 1.00 20.26 ? 123 ASP B C 1 ATOM 5001 O O . ASP B 1 123 ? -80.131 3.686 268.048 1.00 20.50 ? 123 ASP B O 1 ATOM 5002 C CB . ASP B 1 123 ? -80.986 4.609 264.948 1.00 21.57 ? 123 ASP B CB 1 ATOM 5003 C CG . ASP B 1 123 ? -80.023 4.119 263.884 1.00 22.41 ? 123 ASP B CG 1 ATOM 5004 O OD1 . ASP B 1 123 ? -79.794 2.894 263.808 1.00 25.91 ? 123 ASP B OD1 1 ATOM 5005 O OD2 . ASP B 1 123 ? -79.498 4.958 263.123 1.00 26.88 ? 123 ASP B OD2 1 ATOM 5006 N N . THR B 1 124 ? -79.174 2.517 266.369 1.00 18.76 ? 124 THR B N 1 ATOM 5007 C CA . THR B 1 124 ? -78.034 2.105 267.179 1.00 18.72 ? 124 THR B CA 1 ATOM 5008 C C . THR B 1 124 ? -77.063 3.239 267.479 1.00 20.07 ? 124 THR B C 1 ATOM 5009 O O . THR B 1 124 ? -76.042 2.991 268.130 1.00 20.88 ? 124 THR B O 1 ATOM 5010 C CB . THR B 1 124 ? -77.295 0.955 266.494 1.00 18.95 ? 124 THR B CB 1 ATOM 5011 O OG1 . THR B 1 124 ? -76.907 1.350 265.172 1.00 20.33 ? 124 THR B OG1 1 ATOM 5012 C CG2 . THR B 1 124 ? -78.193 -0.272 266.415 1.00 18.51 ? 124 THR B CG2 1 ATOM 5013 N N . ASP B 1 125 ? -77.339 4.463 267.030 1.00 17.56 ? 125 ASP B N 1 ATOM 5014 C CA . ASP B 1 125 ? -76.531 5.605 267.437 1.00 16.16 ? 125 ASP B CA 1 ATOM 5015 C C . ASP B 1 125 ? -76.971 6.187 268.774 1.00 20.79 ? 125 ASP B C 1 ATOM 5016 O O . ASP B 1 125 ? -76.241 7.004 269.345 1.00 20.39 ? 125 ASP B O 1 ATOM 5017 C CB . ASP B 1 125 ? -76.562 6.693 266.358 1.00 14.75 ? 125 ASP B CB 1 ATOM 5018 C CG . ASP B 1 125 ? -77.968 7.021 265.891 1.00 19.63 ? 125 ASP B CG 1 ATOM 5019 O OD1 . ASP B 1 125 ? -78.925 6.829 266.670 1.00 24.28 ? 125 ASP B OD1 1 ATOM 5020 O OD2 . ASP B 1 125 ? -78.115 7.480 264.739 1.00 17.78 ? 125 ASP B OD2 1 ATOM 5021 N N . GLY B 1 126 ? -78.133 5.789 269.282 1.00 21.30 ? 126 GLY B N 1 ATOM 5022 C CA . GLY B 1 126 ? -78.604 6.245 270.571 1.00 23.53 ? 126 GLY B CA 1 ATOM 5023 C C . GLY B 1 126 ? -79.429 7.511 270.556 1.00 21.21 ? 126 GLY B C 1 ATOM 5024 O O . GLY B 1 126 ? -79.680 8.076 271.627 1.00 26.01 ? 126 GLY B O 1 ATOM 5025 N N . GLY B 1 127 ? -79.867 7.971 269.383 1.00 18.41 ? 127 GLY B N 1 ATOM 5026 C CA . GLY B 1 127 ? -80.654 9.192 269.291 1.00 19.68 ? 127 GLY B CA 1 ATOM 5027 C C . GLY B 1 127 ? -81.980 9.141 270.021 1.00 19.13 ? 127 GLY B C 1 ATOM 5028 O O . GLY B 1 127 ? -82.608 10.191 270.203 1.00 34.71 ? 127 GLY B O 1 ATOM 5029 N N . HIS B 1 128 ? -82.419 7.958 270.440 1.00 20.43 ? 128 HIS B N 1 ATOM 5030 C CA . HIS B 1 128 ? -83.658 7.787 271.184 1.00 21.38 ? 128 HIS B CA 1 ATOM 5031 C C . HIS B 1 128 ? -83.425 7.524 272.665 1.00 19.45 ? 128 HIS B C 1 ATOM 5032 O O . HIS B 1 128 ? -84.394 7.407 273.420 1.00 18.89 ? 128 HIS B O 1 ATOM 5033 C CB . HIS B 1 128 ? -84.469 6.636 270.584 1.00 20.69 ? 128 HIS B CB 1 ATOM 5034 C CG . HIS B 1 128 ? -83.791 5.307 270.698 1.00 20.94 ? 128 HIS B CG 1 ATOM 5035 N ND1 . HIS B 1 128 ? -82.741 4.936 269.886 1.00 20.37 ? 128 HIS B ND1 1 ATOM 5036 C CD2 . HIS B 1 128 ? -84.005 4.265 271.535 1.00 21.18 ? 128 HIS B CD2 1 ATOM 5037 C CE1 . HIS B 1 128 ? -82.340 3.721 270.215 1.00 21.50 ? 128 HIS B CE1 1 ATOM 5038 N NE2 . HIS B 1 128 ? -83.090 3.292 271.213 1.00 24.97 ? 128 HIS B NE2 1 ATOM 5039 N N . LEU B 1 129 ? -82.171 7.427 273.095 1.00 19.12 ? 129 LEU B N 1 ATOM 5040 C CA . LEU B 1 129 ? -81.826 7.057 274.458 1.00 19.71 ? 129 LEU B CA 1 ATOM 5041 C C . LEU B 1 129 ? -81.359 8.274 275.247 1.00 21.72 ? 129 LEU B C 1 ATOM 5042 O O . LEU B 1 129 ? -80.962 9.298 274.683 1.00 26.93 ? 129 LEU B O 1 ATOM 5043 C CB . LEU B 1 129 ? -80.736 5.979 274.470 1.00 20.69 ? 129 LEU B CB 1 ATOM 5044 C CG . LEU B 1 129 ? -81.117 4.628 273.862 1.00 21.24 ? 129 LEU B CG 1 ATOM 5045 C CD1 . LEU B 1 129 ? -79.942 3.668 273.916 1.00 28.71 ? 129 LEU B CD1 1 ATOM 5046 C CD2 . LEU B 1 129 ? -82.322 4.041 274.576 1.00 24.54 ? 129 LEU B CD2 1 ATOM 5047 N N . ALA B 1 130 ? -81.413 8.142 276.590 1.00 22.79 ? 130 ALA B N 1 ATOM 5048 C CA . ALA B 1 130 ? -81.014 9.131 277.577 1.00 22.71 ? 130 ALA B CA 1 ATOM 5049 C C . ALA B 1 130 ? -79.609 8.838 278.092 1.00 27.47 ? 130 ALA B C 1 ATOM 5050 O O . ALA B 1 130 ? -79.190 7.678 278.140 1.00 42.07 ? 130 ALA B O 1 ATOM 5051 C CB . ALA B 1 130 ? -81.995 9.149 278.753 1.00 26.95 ? 130 ALA B CB 1 ATOM 5052 N N . PRO B 1 131 ? -78.859 9.871 278.475 1.00 25.14 ? 131 PRO B N 1 ATOM 5053 C CA . PRO B 1 131 ? -77.479 9.656 278.929 1.00 23.96 ? 131 PRO B CA 1 ATOM 5054 C C . PRO B 1 131 ? -77.416 8.756 280.155 1.00 23.75 ? 131 PRO B C 1 ATOM 5055 O O . PRO B 1 131 ? -78.134 8.958 281.137 1.00 24.43 ? 131 PRO B O 1 ATOM 5056 C CB . PRO B 1 131 ? -76.992 11.073 279.248 1.00 23.82 ? 131 PRO B CB 1 ATOM 5057 C CG . PRO B 1 131 ? -77.804 11.944 278.363 1.00 24.67 ? 131 PRO B CG 1 ATOM 5058 C CD . PRO B 1 131 ? -79.166 11.304 278.327 1.00 42.35 ? 131 PRO B CD 1 ATOM 5059 N N . LEU B 1 132 ? -76.543 7.753 280.087 1.00 23.04 ? 132 LEU B N 1 ATOM 5060 C CA . LEU B 1 132 ? -76.283 6.846 281.204 1.00 27.55 ? 132 LEU B CA 1 ATOM 5061 C C . LEU B 1 132 ? -75.020 7.341 281.901 1.00 26.09 ? 132 LEU B C 1 ATOM 5062 O O . LEU B 1 132 ? -73.900 7.010 281.511 1.00 24.22 ? 132 LEU B O 1 ATOM 5063 C CB . LEU B 1 132 ? -76.143 5.408 280.720 1.00 26.96 ? 132 LEU B CB 1 ATOM 5064 C CG . LEU B 1 132 ? -75.720 4.369 281.761 1.00 23.85 ? 132 LEU B CG 1 ATOM 5065 C CD1 . LEU B 1 132 ? -76.664 4.383 282.951 1.00 24.40 ? 132 LEU B CD1 1 ATOM 5066 C CD2 . LEU B 1 132 ? -75.657 2.983 281.138 1.00 28.01 ? 132 LEU B CD2 1 ATOM 5067 N N . GLU B 1 133 ? -75.208 8.149 282.939 1.00 26.38 ? 133 GLU B N 1 ATOM 5068 C CA . GLU B 1 133 ? -74.086 8.727 283.662 1.00 30.10 ? 133 GLU B CA 1 ATOM 5069 C C . GLU B 1 133 ? -73.524 7.726 284.662 1.00 31.14 ? 133 GLU B C 1 ATOM 5070 O O . GLU B 1 133 ? -74.270 7.001 285.326 1.00 40.92 ? 133 GLU B O 1 ATOM 5071 C CB . GLU B 1 133 ? -74.519 10.006 284.380 1.00 34.55 ? 133 GLU B CB 1 ATOM 5072 C CG . GLU B 1 133 ? -73.387 10.754 285.062 1.00 58.32 ? 133 GLU B CG 1 ATOM 5073 C CD . GLU B 1 133 ? -73.817 12.111 285.579 1.00 47.21 ? 133 GLU B CD 1 ATOM 5074 O OE1 . GLU B 1 133 ? -74.080 13.007 284.750 1.00 46.67 ? 133 GLU B OE1 1 ATOM 5075 O OE2 . GLU B 1 133 ? -73.894 12.281 286.814 1.00 50.67 ? 133 GLU B OE2 1 ATOM 5076 N N . TYR B 1 134 ? -72.197 7.688 284.763 1.00 29.95 ? 134 TYR B N 1 ATOM 5077 C CA . TYR B 1 134 ? -71.524 6.764 285.667 1.00 32.34 ? 134 TYR B CA 1 ATOM 5078 C C . TYR B 1 134 ? -71.533 7.317 287.087 1.00 32.48 ? 134 TYR B C 1 ATOM 5079 O O . TYR B 1 134 ? -70.973 8.387 287.347 1.00 33.91 ? 134 TYR B O 1 ATOM 5080 C CB . TYR B 1 134 ? -70.091 6.511 285.203 1.00 28.96 ? 134 TYR B CB 1 ATOM 5081 C CG . TYR B 1 134 ? -69.236 5.813 286.238 1.00 27.10 ? 134 TYR B CG 1 ATOM 5082 C CD1 . TYR B 1 134 ? -69.382 4.455 286.488 1.00 43.80 ? 134 TYR B CD1 1 ATOM 5083 C CD2 . TYR B 1 134 ? -68.284 6.514 286.967 1.00 26.20 ? 134 TYR B CD2 1 ATOM 5084 C CE1 . TYR B 1 134 ? -68.604 3.815 287.436 1.00 39.19 ? 134 TYR B CE1 1 ATOM 5085 C CE2 . TYR B 1 134 ? -67.502 5.882 287.914 1.00 25.56 ? 134 TYR B CE2 1 ATOM 5086 C CZ . TYR B 1 134 ? -67.666 4.534 288.146 1.00 25.08 ? 134 TYR B CZ 1 ATOM 5087 O OH . TYR B 1 134 ? -66.888 3.904 289.090 1.00 23.49 ? 134 TYR B OH 1 ATOM 5088 N N . THR B 1 135 ? -72.166 6.587 288.001 1.00 32.55 ? 135 THR B N 1 ATOM 5089 C CA . THR B 1 135 ? -72.072 6.900 289.419 1.00 30.66 ? 135 THR B CA 1 ATOM 5090 C C . THR B 1 135 ? -70.752 6.366 289.959 1.00 37.04 ? 135 THR B C 1 ATOM 5091 O O . THR B 1 135 ? -70.410 5.200 289.742 1.00 53.85 ? 135 THR B O 1 ATOM 5092 C CB . THR B 1 135 ? -73.247 6.296 290.186 1.00 37.97 ? 135 THR B CB 1 ATOM 5093 O OG1 . THR B 1 135 ? -74.477 6.806 289.657 1.00 64.43 ? 135 THR B OG1 1 ATOM 5094 C CG2 . THR B 1 135 ? -73.154 6.643 291.664 1.00 38.53 ? 135 THR B CG2 1 ATOM 5095 N N . TRP B 1 136 ? -70.009 7.221 290.656 1.00 29.54 ? 136 TRP B N 1 ATOM 5096 C CA . TRP B 1 136 ? -68.655 6.880 291.083 1.00 28.94 ? 136 TRP B CA 1 ATOM 5097 C C . TRP B 1 136 ? -68.711 5.849 292.205 1.00 27.88 ? 136 TRP B C 1 ATOM 5098 O O . TRP B 1 136 ? -69.190 6.139 293.305 1.00 27.26 ? 136 TRP B O 1 ATOM 5099 C CB . TRP B 1 136 ? -67.916 8.141 291.516 1.00 29.21 ? 136 TRP B CB 1 ATOM 5100 C CG . TRP B 1 136 ? -67.772 9.124 290.396 1.00 28.87 ? 136 TRP B CG 1 ATOM 5101 C CD1 . TRP B 1 136 ? -68.635 10.130 290.072 1.00 30.74 ? 136 TRP B CD1 1 ATOM 5102 C CD2 . TRP B 1 136 ? -66.716 9.175 289.428 1.00 28.71 ? 136 TRP B CD2 1 ATOM 5103 N NE1 . TRP B 1 136 ? -68.175 10.813 288.973 1.00 31.74 ? 136 TRP B NE1 1 ATOM 5104 C CE2 . TRP B 1 136 ? -66.999 10.246 288.558 1.00 30.32 ? 136 TRP B CE2 1 ATOM 5105 C CE3 . TRP B 1 136 ? -65.555 8.424 289.219 1.00 29.26 ? 136 TRP B CE3 1 ATOM 5106 C CZ2 . TRP B 1 136 ? -66.165 10.584 287.495 1.00 31.38 ? 136 TRP B CZ2 1 ATOM 5107 C CZ3 . TRP B 1 136 ? -64.729 8.762 288.163 1.00 27.03 ? 136 TRP B CZ3 1 ATOM 5108 C CH2 . TRP B 1 136 ? -65.038 9.832 287.315 1.00 27.59 ? 136 TRP B CH2 1 ATOM 5109 N N . LEU B 1 137 ? -68.217 4.646 291.925 1.00 26.91 ? 137 LEU B N 1 ATOM 5110 C CA . LEU B 1 137 ? -68.271 3.525 292.850 1.00 29.00 ? 137 LEU B CA 1 ATOM 5111 C C . LEU B 1 137 ? -66.873 3.158 293.332 1.00 27.38 ? 137 LEU B C 1 ATOM 5112 O O . LEU B 1 137 ? -65.877 3.405 292.646 1.00 27.85 ? 137 LEU B O 1 ATOM 5113 C CB . LEU B 1 137 ? -68.915 2.299 292.194 1.00 27.77 ? 137 LEU B CB 1 ATOM 5114 C CG . LEU B 1 137 ? -70.319 2.442 291.609 1.00 24.69 ? 137 LEU B CG 1 ATOM 5115 C CD1 . LEU B 1 137 ? -70.760 1.133 290.976 1.00 19.93 ? 137 LEU B CD1 1 ATOM 5116 C CD2 . LEU B 1 137 ? -71.305 2.879 292.679 1.00 32.69 ? 137 LEU B CD2 1 ATOM 5117 N N . GLU B 1 138 ? -66.820 2.561 294.520 1.00 27.46 ? 138 GLU B N 1 ATOM 5118 C CA . GLU B 1 138 ? -65.599 1.975 295.094 1.00 31.42 ? 138 GLU B CA 1 ATOM 5119 C C . GLU B 1 138 ? -64.550 3.078 295.226 1.00 37.05 ? 138 GLU B C 1 ATOM 5120 O O . GLU B 1 138 ? -64.858 4.143 295.785 1.00 65.92 ? 138 GLU B O 1 ATOM 5121 C CB . GLU B 1 138 ? -65.187 0.772 294.253 1.00 28.94 ? 138 GLU B CB 1 ATOM 5122 C CG . GLU B 1 138 ? -66.286 -0.257 294.058 1.00 30.08 ? 138 GLU B CG 1 ATOM 5123 C CD . GLU B 1 138 ? -65.797 -1.496 293.337 1.00 22.92 ? 138 GLU B CD 1 ATOM 5124 O OE1 . GLU B 1 138 ? -65.219 -2.381 294.002 1.00 23.46 ? 138 GLU B OE1 1 ATOM 5125 O OE2 . GLU B 1 138 ? -65.987 -1.585 292.106 1.00 21.49 ? 138 GLU B OE2 1 ATOM 5126 N N . ASN B 1 139 ? -63.325 2.878 294.745 1.00 32.50 ? 139 ASN B N 1 ATOM 5127 C CA . ASN B 1 139 ? -62.250 3.849 294.888 1.00 33.90 ? 139 ASN B CA 1 ATOM 5128 C C . ASN B 1 139 ? -61.987 4.631 293.608 1.00 32.43 ? 139 ASN B C 1 ATOM 5129 O O . ASN B 1 139 ? -60.964 5.316 293.513 1.00 31.21 ? 139 ASN B O 1 ATOM 5130 C CB . ASN B 1 139 ? -60.968 3.147 295.340 1.00 43.17 ? 139 ASN B CB 1 ATOM 5131 C CG . ASN B 1 139 ? -61.155 2.367 296.626 1.00 38.04 ? 139 ASN B CG 1 ATOM 5132 O OD1 . ASN B 1 139 ? -61.973 2.728 297.470 1.00 58.45 ? 139 ASN B OD1 1 ATOM 5133 N ND2 . ASN B 1 139 ? -60.396 1.288 296.779 1.00 53.80 ? 139 ASN B ND2 1 ATOM 5134 N N . ASN B 1 140 ? -62.877 4.542 292.624 1.00 31.53 ? 140 ASN B N 1 ATOM 5135 C CA . ASN B 1 140 ? -62.692 5.281 291.382 1.00 27.29 ? 140 ASN B CA 1 ATOM 5136 C C . ASN B 1 140 ? -62.846 6.776 291.631 1.00 25.95 ? 140 ASN B C 1 ATOM 5137 O O . ASN B 1 140 ? -63.845 7.223 292.202 1.00 26.87 ? 140 ASN B O 1 ATOM 5138 C CB . ASN B 1 140 ? -63.695 4.813 290.330 1.00 38.10 ? 140 ASN B CB 1 ATOM 5139 C CG . ASN B 1 140 ? -63.412 3.407 289.841 1.00 43.47 ? 140 ASN B CG 1 ATOM 5140 O OD1 . ASN B 1 140 ? -62.591 3.204 288.947 1.00 48.08 ? 140 ASN B OD1 1 ATOM 5141 N ND2 . ASN B 1 140 ? -64.093 2.428 290.425 1.00 38.93 ? 140 ASN B ND2 1 ATOM 5142 N N . LYS B 1 141 ? -61.851 7.548 291.202 1.00 27.54 ? 141 LYS B N 1 ATOM 5143 C CA . LYS B 1 141 ? -61.846 8.986 291.394 1.00 27.08 ? 141 LYS B CA 1 ATOM 5144 C C . LYS B 1 141 ? -61.695 9.698 290.056 1.00 35.68 ? 141 LYS B C 1 ATOM 5145 O O . LYS B 1 141 ? -61.038 9.183 289.145 1.00 24.75 ? 141 LYS B O 1 ATOM 5146 C CB . LYS B 1 141 ? -60.714 9.414 292.336 1.00 25.20 ? 141 LYS B CB 1 ATOM 5147 C CG . LYS B 1 141 ? -60.817 8.807 293.725 1.00 33.98 ? 141 LYS B CG 1 ATOM 5148 C CD . LYS B 1 141 ? -59.645 9.210 294.602 1.00 32.17 ? 141 LYS B CD 1 ATOM 5149 C CE . LYS B 1 141 ? -59.700 8.504 295.947 1.00 42.33 ? 141 LYS B CE 1 ATOM 5150 N NZ . LYS B 1 141 ? -58.539 8.857 296.811 1.00 36.33 ? 141 LYS B NZ 1 ATOM 5151 N N . PRO B 1 142 ? -62.302 10.875 289.902 1.00 28.29 ? 142 PRO B N 1 ATOM 5152 C CA . PRO B 1 142 ? -62.229 11.584 288.621 1.00 28.31 ? 142 PRO B CA 1 ATOM 5153 C C . PRO B 1 142 ? -60.801 11.971 288.266 1.00 23.10 ? 142 PRO B C 1 ATOM 5154 O O . PRO B 1 142 ? -59.920 12.078 289.121 1.00 24.51 ? 142 PRO B O 1 ATOM 5155 C CB . PRO B 1 142 ? -63.101 12.825 288.850 1.00 26.56 ? 142 PRO B CB 1 ATOM 5156 C CG . PRO B 1 142 ? -63.991 12.464 289.992 1.00 29.25 ? 142 PRO B CG 1 ATOM 5157 C CD . PRO B 1 142 ? -63.172 11.568 290.867 1.00 25.28 ? 142 PRO B CD 1 ATOM 5158 N N . GLY B 1 143 ? -60.583 12.183 286.971 1.00 22.60 ? 143 GLY B N 1 ATOM 5159 C CA . GLY B 1 143 ? -59.269 12.527 286.469 1.00 23.34 ? 143 GLY B CA 1 ATOM 5160 C C . GLY B 1 143 ? -58.776 11.553 285.420 1.00 23.56 ? 143 GLY B C 1 ATOM 5161 O O . GLY B 1 143 ? -58.596 10.365 285.704 1.00 24.47 ? 143 GLY B O 1 ATOM 5162 N N . ARG B 1 144 ? -58.558 12.041 284.203 1.00 23.00 ? 144 ARG B N 1 ATOM 5163 C CA . ARG B 1 144 ? -58.107 11.219 283.091 1.00 25.35 ? 144 ARG B CA 1 ATOM 5164 C C . ARG B 1 144 ? -56.776 11.742 282.572 1.00 30.46 ? 144 ARG B C 1 ATOM 5165 O O . ARG B 1 144 ? -56.548 12.955 282.537 1.00 34.12 ? 144 ARG B O 1 ATOM 5166 C CB . ARG B 1 144 ? -59.140 11.207 281.957 1.00 26.09 ? 144 ARG B CB 1 ATOM 5167 C CG . ARG B 1 144 ? -58.846 10.194 280.861 1.00 27.60 ? 144 ARG B CG 1 ATOM 5168 C CD . ARG B 1 144 ? -59.961 10.136 279.828 1.00 24.08 ? 144 ARG B CD 1 ATOM 5169 N NE . ARG B 1 144 ? -59.964 11.301 278.949 1.00 24.42 ? 144 ARG B NE 1 ATOM 5170 C CZ . ARG B 1 144 ? -60.811 12.319 279.058 1.00 28.28 ? 144 ARG B CZ 1 ATOM 5171 N NH1 . ARG B 1 144 ? -61.731 12.319 280.012 1.00 28.91 ? 144 ARG B NH1 1 ATOM 5172 N NH2 . ARG B 1 144 ? -60.740 13.336 278.211 1.00 55.53 ? 144 ARG B NH2 1 ATOM 5173 N N . ARG B 1 145 ? -55.898 10.822 282.178 1.00 33.78 ? 145 ARG B N 1 ATOM 5174 C CA . ARG B 1 145 ? -54.647 11.215 281.543 1.00 32.96 ? 145 ARG B CA 1 ATOM 5175 C C . ARG B 1 145 ? -54.946 11.913 280.224 1.00 33.73 ? 145 ARG B C 1 ATOM 5176 O O . ARG B 1 145 ? -55.517 11.316 279.307 1.00 32.61 ? 145 ARG B O 1 ATOM 5177 C CB . ARG B 1 145 ? -53.756 9.995 281.321 1.00 56.90 ? 145 ARG B CB 1 ATOM 5178 C CG . ARG B 1 145 ? -52.400 10.329 280.724 1.00 43.64 ? 145 ARG B CG 1 ATOM 5179 C CD . ARG B 1 145 ? -51.589 11.198 281.671 1.00 41.76 ? 145 ARG B CD 1 ATOM 5180 N NE . ARG B 1 145 ? -50.271 11.515 281.130 1.00 38.77 ? 145 ARG B NE 1 ATOM 5181 C CZ . ARG B 1 145 ? -49.165 10.836 281.413 1.00 36.09 ? 145 ARG B CZ 1 ATOM 5182 N NH1 . ARG B 1 145 ? -49.213 9.799 282.237 1.00 33.64 ? 145 ARG B NH1 1 ATOM 5183 N NH2 . ARG B 1 145 ? -48.010 11.196 280.873 1.00 49.76 ? 145 ARG B NH2 1 ATOM 5184 N N . GLU B 1 146 ? -54.555 13.181 280.134 1.00 38.23 ? 146 GLU B N 1 ATOM 5185 C CA . GLU B 1 146 ? -55.025 14.054 279.067 1.00 37.27 ? 146 GLU B CA 1 ATOM 5186 C C . GLU B 1 146 ? -54.191 13.973 277.797 1.00 34.84 ? 146 GLU B C 1 ATOM 5187 O O . GLU B 1 146 ? -54.723 14.204 276.705 1.00 36.33 ? 146 GLU B O 1 ATOM 5188 C CB . GLU B 1 146 ? -55.059 15.499 279.570 1.00 39.93 ? 146 GLU B CB 1 ATOM 5189 C CG . GLU B 1 146 ? -53.932 15.848 280.523 1.00 42.26 ? 146 GLU B CG 1 ATOM 5190 C CD . GLU B 1 146 ? -54.263 17.037 281.403 1.00 60.71 ? 146 GLU B CD 1 ATOM 5191 O OE1 . GLU B 1 146 ? -54.347 18.166 280.876 1.00 67.17 ? 146 GLU B OE1 1 ATOM 5192 O OE2 . GLU B 1 146 ? -54.438 16.842 282.624 1.00 63.54 ? 146 GLU B OE2 1 ATOM 5193 N N . ASP B 1 147 ? -52.906 13.650 277.901 1.00 35.90 ? 147 ASP B N 1 ATOM 5194 C CA . ASP B 1 147 ? -52.019 13.662 276.747 1.00 39.34 ? 147 ASP B CA 1 ATOM 5195 C C . ASP B 1 147 ? -51.751 12.277 276.175 1.00 54.87 ? 147 ASP B C 1 ATOM 5196 O O . ASP B 1 147 ? -51.089 12.172 275.137 1.00 66.40 ? 147 ASP B O 1 ATOM 5197 C CB . ASP B 1 147 ? -50.691 14.333 277.114 1.00 43.72 ? 147 ASP B CB 1 ATOM 5198 C CG . ASP B 1 147 ? -50.024 13.687 278.310 1.00 54.02 ? 147 ASP B CG 1 ATOM 5199 O OD1 . ASP B 1 147 ? -50.748 13.234 279.222 1.00 54.83 ? 147 ASP B OD1 1 ATOM 5200 O OD2 . ASP B 1 147 ? -48.777 13.631 278.339 1.00 56.27 ? 147 ASP B OD2 1 ATOM 5201 N N . LYS B 1 148 ? -52.243 11.216 276.812 1.00 42.09 ? 148 LYS B N 1 ATOM 5202 C CA . LYS B 1 148 ? -51.945 9.861 276.372 1.00 37.67 ? 148 LYS B CA 1 ATOM 5203 C C . LYS B 1 148 ? -53.204 9.006 276.430 1.00 32.18 ? 148 LYS B C 1 ATOM 5204 O O . LYS B 1 148 ? -54.191 9.355 277.083 1.00 31.85 ? 148 LYS B O 1 ATOM 5205 C CB . LYS B 1 148 ? -50.822 9.238 277.214 1.00 39.92 ? 148 LYS B CB 1 ATOM 5206 C CG . LYS B 1 148 ? -49.493 9.967 277.072 1.00 49.03 ? 148 LYS B CG 1 ATOM 5207 C CD . LYS B 1 148 ? -48.385 9.308 277.869 1.00 40.91 ? 148 LYS B CD 1 ATOM 5208 C CE . LYS B 1 148 ? -47.021 9.824 277.436 1.00 54.88 ? 148 LYS B CE 1 ATOM 5209 N NZ . LYS B 1 148 ? -47.126 10.863 276.370 1.00 59.46 ? 148 LYS B NZ 1 ATOM 5210 N N . ILE B 1 149 ? -53.150 7.874 275.734 1.00 32.96 ? 149 ILE B N 1 ATOM 5211 C CA . ILE B 1 149 ? -54.312 7.008 275.569 1.00 30.72 ? 149 ILE B CA 1 ATOM 5212 C C . ILE B 1 149 ? -54.465 6.124 276.798 1.00 27.03 ? 149 ILE B C 1 ATOM 5213 O O . ILE B 1 149 ? -53.501 5.499 277.254 1.00 26.61 ? 149 ILE B O 1 ATOM 5214 C CB . ILE B 1 149 ? -54.178 6.161 274.293 1.00 26.77 ? 149 ILE B CB 1 ATOM 5215 C CG1 . ILE B 1 149 ? -54.108 7.062 273.060 1.00 25.55 ? 149 ILE B CG1 1 ATOM 5216 C CG2 . ILE B 1 149 ? -55.335 5.182 274.176 1.00 25.95 ? 149 ILE B CG2 1 ATOM 5217 C CD1 . ILE B 1 149 ? -55.347 7.900 272.848 1.00 35.30 ? 149 ILE B CD1 1 ATOM 5218 N N . VAL B 1 150 ? -55.681 6.064 277.335 1.00 26.06 ? 150 VAL B N 1 ATOM 5219 C CA . VAL B 1 150 ? -56.011 5.212 278.474 1.00 22.96 ? 150 VAL B CA 1 ATOM 5220 C C . VAL B 1 150 ? -57.194 4.350 278.053 1.00 26.19 ? 150 VAL B C 1 ATOM 5221 O O . VAL B 1 150 ? -58.342 4.811 278.062 1.00 33.55 ? 150 VAL B O 1 ATOM 5222 C CB . VAL B 1 150 ? -56.333 6.017 279.737 1.00 23.30 ? 150 VAL B CB 1 ATOM 5223 C CG1 . VAL B 1 150 ? -56.734 5.085 280.870 1.00 22.42 ? 150 VAL B CG1 1 ATOM 5224 C CG2 . VAL B 1 150 ? -55.138 6.861 280.140 1.00 28.75 ? 150 VAL B CG2 1 ATOM 5225 N N . ALA B 1 151 ? -56.924 3.104 277.683 1.00 32.53 ? 151 ALA B N 1 ATOM 5226 C CA . ALA B 1 151 ? -57.949 2.172 277.241 1.00 30.14 ? 151 ALA B CA 1 ATOM 5227 C C . ALA B 1 151 ? -58.183 1.102 278.299 1.00 23.23 ? 151 ALA B C 1 ATOM 5228 O O . ALA B 1 151 ? -57.405 0.937 279.241 1.00 28.24 ? 151 ALA B O 1 ATOM 5229 C CB . ALA B 1 151 ? -57.561 1.530 275.904 1.00 27.18 ? 151 ALA B CB 1 ATOM 5230 N N . ALA B 1 152 ? -59.282 0.371 278.130 1.00 26.40 ? 152 ALA B N 1 ATOM 5231 C CA . ALA B 1 152 ? -59.633 -0.712 279.037 1.00 23.36 ? 152 ALA B CA 1 ATOM 5232 C C . ALA B 1 152 ? -60.520 -1.698 278.295 1.00 20.91 ? 152 ALA B C 1 ATOM 5233 O O . ALA B 1 152 ? -61.174 -1.352 277.308 1.00 22.88 ? 152 ALA B O 1 ATOM 5234 C CB . ALA B 1 152 ? -60.333 -0.192 280.297 1.00 18.54 ? 152 ALA B CB 1 ATOM 5235 N N . TYR B 1 153 ? -60.535 -2.932 278.788 1.00 17.09 ? 153 TYR B N 1 ATOM 5236 C CA . TYR B 1 153 ? -61.274 -4.021 278.166 1.00 18.70 ? 153 TYR B CA 1 ATOM 5237 C C . TYR B 1 153 ? -62.509 -4.352 278.991 1.00 18.43 ? 153 TYR B C 1 ATOM 5238 O O . TYR B 1 153 ? -62.412 -4.571 280.203 1.00 18.77 ? 153 TYR B O 1 ATOM 5239 C CB . TYR B 1 153 ? -60.399 -5.265 278.024 1.00 19.71 ? 153 TYR B CB 1 ATOM 5240 C CG . TYR B 1 153 ? -59.692 -5.387 276.695 1.00 19.88 ? 153 TYR B CG 1 ATOM 5241 C CD1 . TYR B 1 153 ? -60.336 -5.936 275.595 1.00 20.12 ? 153 TYR B CD1 1 ATOM 5242 C CD2 . TYR B 1 153 ? -58.377 -4.973 276.543 1.00 21.31 ? 153 TYR B CD2 1 ATOM 5243 C CE1 . TYR B 1 153 ? -59.696 -6.057 274.378 1.00 21.95 ? 153 TYR B CE1 1 ATOM 5244 C CE2 . TYR B 1 153 ? -57.726 -5.092 275.330 1.00 22.96 ? 153 TYR B CE2 1 ATOM 5245 C CZ . TYR B 1 153 ? -58.391 -5.633 274.250 1.00 22.10 ? 153 TYR B CZ 1 ATOM 5246 O OH . TYR B 1 153 ? -57.751 -5.753 273.038 1.00 23.04 ? 153 TYR B OH 1 ATOM 5247 N N . PHE B 1 154 ? -63.661 -4.398 278.328 1.00 18.27 ? 154 PHE B N 1 ATOM 5248 C CA . PHE B 1 154 ? -64.911 -4.838 278.931 1.00 19.30 ? 154 PHE B CA 1 ATOM 5249 C C . PHE B 1 154 ? -65.275 -6.201 278.361 1.00 20.68 ? 154 PHE B C 1 ATOM 5250 O O . PHE B 1 154 ? -65.334 -6.371 277.139 1.00 17.47 ? 154 PHE B O 1 ATOM 5251 C CB . PHE B 1 154 ? -66.033 -3.832 278.670 1.00 18.26 ? 154 PHE B CB 1 ATOM 5252 C CG . PHE B 1 154 ? -67.379 -4.281 279.166 1.00 20.30 ? 154 PHE B CG 1 ATOM 5253 C CD1 . PHE B 1 154 ? -67.715 -4.157 280.504 1.00 20.52 ? 154 PHE B CD1 1 ATOM 5254 C CD2 . PHE B 1 154 ? -68.309 -4.822 278.294 1.00 19.02 ? 154 PHE B CD2 1 ATOM 5255 C CE1 . PHE B 1 154 ? -68.951 -4.569 280.964 1.00 20.12 ? 154 PHE B CE1 1 ATOM 5256 C CE2 . PHE B 1 154 ? -69.547 -5.236 278.748 1.00 17.75 ? 154 PHE B CE2 1 ATOM 5257 C CZ . PHE B 1 154 ? -69.868 -5.108 280.085 1.00 17.10 ? 154 PHE B CZ 1 ATOM 5258 N N . VAL B 1 155 ? -65.513 -7.166 279.242 1.00 19.97 ? 155 VAL B N 1 ATOM 5259 C CA . VAL B 1 155 ? -65.823 -8.530 278.833 1.00 21.03 ? 155 VAL B CA 1 ATOM 5260 C C . VAL B 1 155 ? -67.327 -8.673 278.653 1.00 21.87 ? 155 VAL B C 1 ATOM 5261 O O . VAL B 1 155 ? -68.119 -8.170 279.460 1.00 19.94 ? 155 VAL B O 1 ATOM 5262 C CB . VAL B 1 155 ? -65.279 -9.547 279.854 1.00 22.83 ? 155 VAL B CB 1 ATOM 5263 C CG1 . VAL B 1 155 ? -63.760 -9.598 279.790 1.00 20.78 ? 155 VAL B CG1 1 ATOM 5264 C CG2 . VAL B 1 155 ? -65.738 -9.194 281.258 1.00 36.56 ? 155 VAL B CG2 1 ATOM 5265 N N . GLU B 1 156 ? -67.723 -9.358 277.579 1.00 22.65 ? 156 GLU B N 1 ATOM 5266 C CA . GLU B 1 156 ? -69.143 -9.551 277.297 1.00 22.46 ? 156 GLU B CA 1 ATOM 5267 C C . GLU B 1 156 ? -69.814 -10.389 278.377 1.00 22.79 ? 156 GLU B C 1 ATOM 5268 O O . GLU B 1 156 ? -70.933 -10.085 278.806 1.00 22.78 ? 156 GLU B O 1 ATOM 5269 C CB . GLU B 1 156 ? -69.313 -10.203 275.925 1.00 25.08 ? 156 GLU B CB 1 ATOM 5270 C CG . GLU B 1 156 ? -70.746 -10.545 275.558 1.00 25.53 ? 156 GLU B CG 1 ATOM 5271 C CD . GLU B 1 156 ? -70.880 -10.997 274.117 1.00 26.79 ? 156 GLU B CD 1 ATOM 5272 O OE1 . GLU B 1 156 ? -70.934 -12.221 273.877 1.00 27.30 ? 156 GLU B OE1 1 ATOM 5273 O OE2 . GLU B 1 156 ? -70.930 -10.127 273.222 1.00 26.22 ? 156 GLU B OE2 1 ATOM 5274 N N . TRP B 1 157 ? -69.143 -11.442 278.834 1.00 21.62 ? 157 TRP B N 1 ATOM 5275 C CA . TRP B 1 157 ? -69.681 -12.343 279.843 1.00 20.71 ? 157 TRP B CA 1 ATOM 5276 C C . TRP B 1 157 ? -69.551 -11.801 281.262 1.00 24.46 ? 157 TRP B C 1 ATOM 5277 O O . TRP B 1 157 ? -69.849 -12.528 282.215 1.00 24.00 ? 157 TRP B O 1 ATOM 5278 C CB . TRP B 1 157 ? -68.988 -13.704 279.742 1.00 22.14 ? 157 TRP B CB 1 ATOM 5279 C CG . TRP B 1 157 ? -67.506 -13.626 279.936 1.00 26.72 ? 157 TRP B CG 1 ATOM 5280 C CD1 . TRP B 1 157 ? -66.819 -13.825 281.097 1.00 28.08 ? 157 TRP B CD1 1 ATOM 5281 C CD2 . TRP B 1 157 ? -66.526 -13.318 278.938 1.00 24.26 ? 157 TRP B CD2 1 ATOM 5282 N NE1 . TRP B 1 157 ? -65.471 -13.664 280.883 1.00 25.69 ? 157 TRP B NE1 1 ATOM 5283 C CE2 . TRP B 1 157 ? -65.265 -13.352 279.565 1.00 22.16 ? 157 TRP B CE2 1 ATOM 5284 C CE3 . TRP B 1 157 ? -66.592 -13.019 277.574 1.00 25.23 ? 157 TRP B CE3 1 ATOM 5285 C CZ2 . TRP B 1 157 ? -64.082 -13.099 278.877 1.00 28.44 ? 157 TRP B CZ2 1 ATOM 5286 C CZ3 . TRP B 1 157 ? -65.416 -12.767 276.892 1.00 25.71 ? 157 TRP B CZ3 1 ATOM 5287 C CH2 . TRP B 1 157 ? -64.178 -12.809 277.544 1.00 29.42 ? 157 TRP B CH2 1 ATOM 5288 N N . GLY B 1 158 ? -69.118 -10.551 281.427 1.00 26.02 ? 158 GLY B N 1 ATOM 5289 C CA . GLY B 1 158 ? -68.970 -9.985 282.756 1.00 25.44 ? 158 GLY B CA 1 ATOM 5290 C C . GLY B 1 158 ? -70.271 -9.619 283.435 1.00 25.72 ? 158 GLY B C 1 ATOM 5291 O O . GLY B 1 158 ? -70.259 -9.315 284.633 1.00 26.76 ? 158 GLY B O 1 ATOM 5292 N N . VAL B 1 159 ? -71.392 -9.644 282.705 1.00 25.17 ? 159 VAL B N 1 ATOM 5293 C CA . VAL B 1 159 ? -72.683 -9.280 283.278 1.00 23.77 ? 159 VAL B CA 1 ATOM 5294 C C . VAL B 1 159 ? -73.364 -10.446 283.976 1.00 23.86 ? 159 VAL B C 1 ATOM 5295 O O . VAL B 1 159 ? -74.506 -10.301 284.434 1.00 22.15 ? 159 VAL B O 1 ATOM 5296 C CB . VAL B 1 159 ? -73.625 -8.711 282.198 1.00 21.86 ? 159 VAL B CB 1 ATOM 5297 C CG1 . VAL B 1 159 ? -73.017 -7.471 281.573 1.00 20.10 ? 159 VAL B CG1 1 ATOM 5298 C CG2 . VAL B 1 159 ? -73.914 -9.764 281.145 1.00 20.19 ? 159 VAL B CG2 1 ATOM 5299 N N . TYR B 1 160 ? -72.707 -11.601 284.068 1.00 24.83 ? 160 TYR B N 1 ATOM 5300 C CA . TYR B 1 160 ? -73.299 -12.752 284.739 1.00 26.06 ? 160 TYR B CA 1 ATOM 5301 C C . TYR B 1 160 ? -72.747 -12.905 286.150 1.00 25.71 ? 160 TYR B C 1 ATOM 5302 O O . TYR B 1 160 ? -73.061 -12.102 287.035 1.00 33.96 ? 160 TYR B O 1 ATOM 5303 C CB . TYR B 1 160 ? -73.061 -14.027 283.930 1.00 23.94 ? 160 TYR B CB 1 ATOM 5304 C CG . TYR B 1 160 ? -73.665 -13.989 282.547 1.00 21.21 ? 160 TYR B CG 1 ATOM 5305 C CD1 . TYR B 1 160 ? -75.039 -13.898 282.375 1.00 23.88 ? 160 TYR B CD1 1 ATOM 5306 C CD2 . TYR B 1 160 ? -72.866 -14.055 281.413 1.00 21.56 ? 160 TYR B CD2 1 ATOM 5307 C CE1 . TYR B 1 160 ? -75.600 -13.863 281.117 1.00 22.52 ? 160 TYR B CE1 1 ATOM 5308 C CE2 . TYR B 1 160 ? -73.420 -14.023 280.148 1.00 22.39 ? 160 TYR B CE2 1 ATOM 5309 C CZ . TYR B 1 160 ? -74.788 -13.928 280.007 1.00 21.48 ? 160 TYR B CZ 1 ATOM 5310 O OH . TYR B 1 160 ? -75.351 -13.895 278.755 1.00 22.46 ? 160 TYR B OH 1 ATOM 5311 N N . GLY B 1 161 ? -71.928 -13.935 286.367 1.00 20.22 ? 161 GLY B N 1 ATOM 5312 C CA . GLY B 1 161 ? -71.396 -14.175 287.698 1.00 19.70 ? 161 GLY B CA 1 ATOM 5313 C C . GLY B 1 161 ? -70.536 -13.033 288.201 1.00 20.27 ? 161 GLY B C 1 ATOM 5314 O O . GLY B 1 161 ? -70.544 -12.715 289.393 1.00 24.87 ? 161 GLY B O 1 ATOM 5315 N N . ARG B 1 162 ? -69.785 -12.396 287.300 1.00 23.31 ? 162 ARG B N 1 ATOM 5316 C CA . ARG B 1 162 ? -68.952 -11.268 287.703 1.00 25.06 ? 162 ARG B CA 1 ATOM 5317 C C . ARG B 1 162 ? -69.792 -10.062 288.100 1.00 24.39 ? 162 ARG B C 1 ATOM 5318 O O . ARG B 1 162 ? -69.338 -9.232 288.895 1.00 27.81 ? 162 ARG B O 1 ATOM 5319 C CB . ARG B 1 162 ? -67.982 -10.905 286.579 1.00 22.77 ? 162 ARG B CB 1 ATOM 5320 C CG . ARG B 1 162 ? -66.930 -11.972 286.320 1.00 25.82 ? 162 ARG B CG 1 ATOM 5321 C CD . ARG B 1 162 ? -66.029 -11.611 285.152 1.00 25.32 ? 162 ARG B CD 1 ATOM 5322 N NE . ARG B 1 162 ? -64.818 -12.427 285.132 1.00 26.80 ? 162 ARG B NE 1 ATOM 5323 C CZ . ARG B 1 162 ? -64.746 -13.648 284.611 1.00 29.45 ? 162 ARG B CZ 1 ATOM 5324 N NH1 . ARG B 1 162 ? -65.818 -14.204 284.065 1.00 44.89 ? 162 ARG B NH1 1 ATOM 5325 N NH2 . ARG B 1 162 ? -63.600 -14.315 284.639 1.00 28.75 ? 162 ARG B NH2 1 ATOM 5326 N N . ASN B 1 163 ? -71.010 -9.955 287.566 1.00 22.66 ? 163 ASN B N 1 ATOM 5327 C CA . ASN B 1 163 ? -71.955 -8.895 287.920 1.00 23.42 ? 163 ASN B CA 1 ATOM 5328 C C . ASN B 1 163 ? -71.333 -7.512 287.716 1.00 22.96 ? 163 ASN B C 1 ATOM 5329 O O . ASN B 1 163 ? -71.158 -6.730 288.652 1.00 25.24 ? 163 ASN B O 1 ATOM 5330 C CB . ASN B 1 163 ? -72.455 -9.071 289.358 1.00 23.87 ? 163 ASN B CB 1 ATOM 5331 C CG . ASN B 1 163 ? -73.672 -8.223 289.659 1.00 22.92 ? 163 ASN B CG 1 ATOM 5332 O OD1 . ASN B 1 163 ? -74.549 -8.052 288.812 1.00 18.54 ? 163 ASN B OD1 1 ATOM 5333 N ND2 . ASN B 1 163 ? -73.733 -7.683 290.870 1.00 31.16 ? 163 ASN B ND2 1 ATOM 5334 N N . PHE B 1 164 ? -70.997 -7.224 286.462 1.00 19.68 ? 164 PHE B N 1 ATOM 5335 C CA . PHE B 1 164 ? -70.364 -5.960 286.088 1.00 19.32 ? 164 PHE B CA 1 ATOM 5336 C C . PHE B 1 164 ? -70.874 -5.527 284.723 1.00 18.33 ? 164 PHE B C 1 ATOM 5337 O O . PHE B 1 164 ? -70.242 -5.783 283.691 1.00 18.96 ? 164 PHE B O 1 ATOM 5338 C CB . PHE B 1 164 ? -68.839 -6.088 286.087 1.00 19.93 ? 164 PHE B CB 1 ATOM 5339 C CG . PHE B 1 164 ? -68.121 -4.785 286.284 1.00 15.80 ? 164 PHE B CG 1 ATOM 5340 C CD1 . PHE B 1 164 ? -67.843 -3.962 285.206 1.00 14.54 ? 164 PHE B CD1 1 ATOM 5341 C CD2 . PHE B 1 164 ? -67.714 -4.387 287.546 1.00 16.74 ? 164 PHE B CD2 1 ATOM 5342 C CE1 . PHE B 1 164 ? -67.180 -2.764 285.384 1.00 16.51 ? 164 PHE B CE1 1 ATOM 5343 C CE2 . PHE B 1 164 ? -67.049 -3.191 287.731 1.00 17.18 ? 164 PHE B CE2 1 ATOM 5344 C CZ . PHE B 1 164 ? -66.782 -2.379 286.648 1.00 18.90 ? 164 PHE B CZ 1 ATOM 5345 N N . PRO B 1 165 ? -72.021 -4.864 284.679 1.00 16.99 ? 165 PRO B N 1 ATOM 5346 C CA . PRO B 1 165 ? -72.536 -4.326 283.418 1.00 19.42 ? 165 PRO B CA 1 ATOM 5347 C C . PRO B 1 165 ? -71.770 -3.068 283.019 1.00 20.89 ? 165 PRO B C 1 ATOM 5348 O O . PRO B 1 165 ? -70.835 -2.636 283.690 1.00 16.65 ? 165 PRO B O 1 ATOM 5349 C CB . PRO B 1 165 ? -73.998 -4.021 283.745 1.00 19.86 ? 165 PRO B CB 1 ATOM 5350 C CG . PRO B 1 165 ? -73.984 -3.720 285.204 1.00 18.39 ? 165 PRO B CG 1 ATOM 5351 C CD . PRO B 1 165 ? -72.945 -4.627 285.801 1.00 16.44 ? 165 PRO B CD 1 ATOM 5352 N N . VAL B 1 166 ? -72.194 -2.475 281.900 1.00 19.56 ? 166 VAL B N 1 ATOM 5353 C CA . VAL B 1 166 ? -71.517 -1.288 281.387 1.00 21.11 ? 166 VAL B CA 1 ATOM 5354 C C . VAL B 1 166 ? -71.689 -0.107 282.334 1.00 19.79 ? 166 VAL B C 1 ATOM 5355 O O . VAL B 1 166 ? -70.781 0.722 282.475 1.00 17.91 ? 166 VAL B O 1 ATOM 5356 C CB . VAL B 1 166 ? -72.028 -0.955 279.974 1.00 21.13 ? 166 VAL B CB 1 ATOM 5357 C CG1 . VAL B 1 166 ? -71.299 0.255 279.416 1.00 20.11 ? 166 VAL B CG1 1 ATOM 5358 C CG2 . VAL B 1 166 ? -71.860 -2.155 279.056 1.00 20.52 ? 166 VAL B CG2 1 ATOM 5359 N N . ASP B 1 167 ? -72.837 -0.014 283.009 1.00 20.81 ? 167 ASP B N 1 ATOM 5360 C CA . ASP B 1 167 ? -73.098 1.109 283.903 1.00 18.84 ? 167 ASP B CA 1 ATOM 5361 C C . ASP B 1 167 ? -72.154 1.151 285.099 1.00 17.17 ? 167 ASP B C 1 ATOM 5362 O O . ASP B 1 167 ? -72.162 2.145 285.834 1.00 21.69 ? 167 ASP B O 1 ATOM 5363 C CB . ASP B 1 167 ? -74.552 1.071 284.382 1.00 16.49 ? 167 ASP B CB 1 ATOM 5364 C CG . ASP B 1 167 ? -74.920 -0.248 285.031 1.00 15.26 ? 167 ASP B CG 1 ATOM 5365 O OD1 . ASP B 1 167 ? -74.544 -0.465 286.201 1.00 13.40 ? 167 ASP B OD1 1 ATOM 5366 O OD2 . ASP B 1 167 ? -75.596 -1.064 284.371 1.00 16.72 ? 167 ASP B OD2 1 ATOM 5367 N N . LYS B 1 168 ? -71.348 0.112 285.313 1.00 16.20 ? 168 LYS B N 1 ATOM 5368 C CA . LYS B 1 168 ? -70.323 0.125 286.346 1.00 18.53 ? 168 LYS B CA 1 ATOM 5369 C C . LYS B 1 168 ? -68.954 0.541 285.824 1.00 19.98 ? 168 LYS B C 1 ATOM 5370 O O . LYS B 1 168 ? -68.053 0.792 286.630 1.00 17.75 ? 168 LYS B O 1 ATOM 5371 C CB . LYS B 1 168 ? -70.207 -1.256 287.004 1.00 17.74 ? 168 LYS B CB 1 ATOM 5372 C CG . LYS B 1 168 ? -71.432 -1.691 287.789 1.00 18.04 ? 168 LYS B CG 1 ATOM 5373 C CD . LYS B 1 168 ? -71.161 -2.990 288.533 1.00 21.34 ? 168 LYS B CD 1 ATOM 5374 C CE . LYS B 1 168 ? -72.327 -3.377 289.427 1.00 26.89 ? 168 LYS B CE 1 ATOM 5375 N NZ . LYS B 1 168 ? -72.037 -4.616 290.202 1.00 50.51 ? 168 LYS B NZ 1 ATOM 5376 N N . VAL B 1 169 ? -68.778 0.620 284.509 1.00 18.68 ? 169 VAL B N 1 ATOM 5377 C CA . VAL B 1 169 ? -67.476 0.909 283.913 1.00 17.47 ? 169 VAL B CA 1 ATOM 5378 C C . VAL B 1 169 ? -67.150 2.387 284.095 1.00 19.81 ? 169 VAL B C 1 ATOM 5379 O O . VAL B 1 169 ? -67.892 3.251 283.605 1.00 20.29 ? 169 VAL B O 1 ATOM 5380 C CB . VAL B 1 169 ? -67.445 0.519 282.427 1.00 14.69 ? 169 VAL B CB 1 ATOM 5381 C CG1 . VAL B 1 169 ? -66.071 0.786 281.841 1.00 14.62 ? 169 VAL B CG1 1 ATOM 5382 C CG2 . VAL B 1 169 ? -67.833 -0.940 282.254 1.00 14.57 ? 169 VAL B CG2 1 ATOM 5383 N N . PRO B 1 170 ? -66.064 2.723 284.790 1.00 18.77 ? 170 PRO B N 1 ATOM 5384 C CA . PRO B 1 170 ? -65.692 4.137 284.943 1.00 19.56 ? 170 PRO B CA 1 ATOM 5385 C C . PRO B 1 170 ? -65.175 4.744 283.648 1.00 19.67 ? 170 PRO B C 1 ATOM 5386 O O . PRO B 1 170 ? -63.967 4.935 283.475 1.00 22.45 ? 170 PRO B O 1 ATOM 5387 C CB . PRO B 1 170 ? -64.603 4.099 286.024 1.00 21.43 ? 170 PRO B CB 1 ATOM 5388 C CG . PRO B 1 170 ? -64.068 2.710 285.980 1.00 21.65 ? 170 PRO B CG 1 ATOM 5389 C CD . PRO B 1 170 ? -65.198 1.825 285.572 1.00 18.76 ? 170 PRO B CD 1 ATOM 5390 N N . LEU B 1 171 ? -66.090 5.052 282.735 1.00 21.05 ? 171 LEU B N 1 ATOM 5391 C CA . LEU B 1 171 ? -65.775 5.638 281.436 1.00 24.15 ? 171 LEU B CA 1 ATOM 5392 C C . LEU B 1 171 ? -65.205 7.056 281.506 1.00 22.02 ? 171 LEU B C 1 ATOM 5393 O O . LEU B 1 171 ? -64.370 7.405 280.661 1.00 21.51 ? 171 LEU B O 1 ATOM 5394 C CB . LEU B 1 171 ? -67.019 5.624 280.547 1.00 21.59 ? 171 LEU B CB 1 ATOM 5395 C CG . LEU B 1 171 ? -67.570 4.229 280.255 1.00 19.80 ? 171 LEU B CG 1 ATOM 5396 C CD1 . LEU B 1 171 ? -68.884 4.323 279.509 1.00 38.73 ? 171 LEU B CD1 1 ATOM 5397 C CD2 . LEU B 1 171 ? -66.558 3.425 279.459 1.00 25.52 ? 171 LEU B CD2 1 ATOM 5398 N N . PRO B 1 172 ? -65.627 7.915 282.447 1.00 21.83 ? 172 PRO B N 1 ATOM 5399 C CA . PRO B 1 172 ? -64.994 9.244 282.532 1.00 24.68 ? 172 PRO B CA 1 ATOM 5400 C C . PRO B 1 172 ? -63.483 9.200 282.693 1.00 29.07 ? 172 PRO B C 1 ATOM 5401 O O . PRO B 1 172 ? -62.800 10.149 282.286 1.00 37.28 ? 172 PRO B O 1 ATOM 5402 C CB . PRO B 1 172 ? -65.672 9.876 283.753 1.00 26.16 ? 172 PRO B CB 1 ATOM 5403 C CG . PRO B 1 172 ? -67.000 9.247 283.797 1.00 44.62 ? 172 PRO B CG 1 ATOM 5404 C CD . PRO B 1 172 ? -66.817 7.837 283.318 1.00 23.30 ? 172 PRO B CD 1 ATOM 5405 N N . ASN B 1 173 ? -62.936 8.131 283.272 1.00 26.96 ? 173 ASN B N 1 ATOM 5406 C CA . ASN B 1 173 ? -61.496 7.970 283.411 1.00 22.86 ? 173 ASN B CA 1 ATOM 5407 C C . ASN B 1 173 ? -60.901 7.097 282.312 1.00 23.02 ? 173 ASN B C 1 ATOM 5408 O O . ASN B 1 173 ? -59.818 6.531 282.497 1.00 24.44 ? 173 ASN B O 1 ATOM 5409 C CB . ASN B 1 173 ? -61.158 7.395 284.786 1.00 21.97 ? 173 ASN B CB 1 ATOM 5410 C CG . ASN B 1 173 ? -61.559 8.318 285.917 1.00 25.86 ? 173 ASN B CG 1 ATOM 5411 O OD1 . ASN B 1 173 ? -61.766 9.514 285.712 1.00 24.99 ? 173 ASN B OD1 1 ATOM 5412 N ND2 . ASN B 1 173 ? -61.668 7.769 287.120 1.00 29.15 ? 173 ASN B ND2 1 ATOM 5413 N N . LEU B 1 174 ? -61.584 6.978 281.176 1.00 21.68 ? 174 LEU B N 1 ATOM 5414 C CA . LEU B 1 174 ? -61.110 6.170 280.063 1.00 21.90 ? 174 LEU B CA 1 ATOM 5415 C C . LEU B 1 174 ? -61.294 6.934 278.763 1.00 21.86 ? 174 LEU B C 1 ATOM 5416 O O . LEU B 1 174 ? -62.307 7.612 278.568 1.00 22.92 ? 174 LEU B O 1 ATOM 5417 C CB . LEU B 1 174 ? -61.854 4.830 279.981 1.00 21.58 ? 174 LEU B CB 1 ATOM 5418 C CG . LEU B 1 174 ? -61.693 3.867 281.156 1.00 19.58 ? 174 LEU B CG 1 ATOM 5419 C CD1 . LEU B 1 174 ? -62.589 2.655 280.970 1.00 27.19 ? 174 LEU B CD1 1 ATOM 5420 C CD2 . LEU B 1 174 ? -60.243 3.443 281.289 1.00 20.43 ? 174 LEU B CD2 1 ATOM 5421 N N . SER B 1 175 ? -60.308 6.820 277.876 1.00 22.26 ? 175 SER B N 1 ATOM 5422 C CA . SER B 1 175 ? -60.415 7.397 276.543 1.00 22.92 ? 175 SER B CA 1 ATOM 5423 C C . SER B 1 175 ? -60.946 6.401 275.525 1.00 24.82 ? 175 SER B C 1 ATOM 5424 O O . SER B 1 175 ? -61.597 6.805 274.554 1.00 22.50 ? 175 SER B O 1 ATOM 5425 C CB . SER B 1 175 ? -59.054 7.921 276.079 1.00 22.22 ? 175 SER B CB 1 ATOM 5426 O OG . SER B 1 175 ? -58.149 6.854 275.858 1.00 22.46 ? 175 SER B OG 1 ATOM 5427 N N . HIS B 1 176 ? -60.685 5.112 275.725 1.00 26.31 ? 176 HIS B N 1 ATOM 5428 C CA . HIS B 1 176 ? -61.144 4.072 274.819 1.00 26.39 ? 176 HIS B CA 1 ATOM 5429 C C . HIS B 1 176 ? -61.709 2.909 275.619 1.00 27.73 ? 176 HIS B C 1 ATOM 5430 O O . HIS B 1 176 ? -61.187 2.563 276.682 1.00 24.83 ? 176 HIS B O 1 ATOM 5431 C CB . HIS B 1 176 ? -60.012 3.580 273.910 1.00 25.15 ? 176 HIS B CB 1 ATOM 5432 C CG . HIS B 1 176 ? -59.536 4.606 272.931 1.00 24.42 ? 176 HIS B CG 1 ATOM 5433 N ND1 . HIS B 1 176 ? -58.763 5.685 273.300 1.00 23.84 ? 176 HIS B ND1 1 ATOM 5434 C CD2 . HIS B 1 176 ? -59.727 4.719 271.595 1.00 25.92 ? 176 HIS B CD2 1 ATOM 5435 C CE1 . HIS B 1 176 ? -58.496 6.418 272.234 1.00 30.26 ? 176 HIS B CE1 1 ATOM 5436 N NE2 . HIS B 1 176 ? -59.069 5.854 271.186 1.00 34.17 ? 176 HIS B NE2 1 ATOM 5437 N N . LEU B 1 177 ? -62.781 2.315 275.100 1.00 26.50 ? 177 LEU B N 1 ATOM 5438 C CA . LEU B 1 177 ? -63.412 1.144 275.694 1.00 25.67 ? 177 LEU B CA 1 ATOM 5439 C C . LEU B 1 177 ? -63.386 0.029 274.660 1.00 22.14 ? 177 LEU B C 1 ATOM 5440 O O . LEU B 1 177 ? -63.970 0.166 273.580 1.00 26.56 ? 177 LEU B O 1 ATOM 5441 C CB . LEU B 1 177 ? -64.846 1.455 276.135 1.00 23.56 ? 177 LEU B CB 1 ATOM 5442 C CG . LEU B 1 177 ? -65.562 0.506 277.104 1.00 17.98 ? 177 LEU B CG 1 ATOM 5443 C CD1 . LEU B 1 177 ? -66.112 -0.733 276.405 1.00 19.33 ? 177 LEU B CD1 1 ATOM 5444 C CD2 . LEU B 1 177 ? -64.638 0.113 278.246 1.00 18.94 ? 177 LEU B CD2 1 ATOM 5445 N N . LEU B 1 178 ? -62.707 -1.067 274.988 1.00 19.56 ? 178 LEU B N 1 ATOM 5446 C CA . LEU B 1 178 ? -62.526 -2.184 274.069 1.00 21.94 ? 178 LEU B CA 1 ATOM 5447 C C . LEU B 1 178 ? -63.496 -3.296 274.453 1.00 21.53 ? 178 LEU B C 1 ATOM 5448 O O . LEU B 1 178 ? -63.354 -3.915 275.513 1.00 21.64 ? 178 LEU B O 1 ATOM 5449 C CB . LEU B 1 178 ? -61.079 -2.669 274.093 1.00 20.90 ? 178 LEU B CB 1 ATOM 5450 C CG . LEU B 1 178 ? -60.055 -1.583 273.748 1.00 24.50 ? 178 LEU B CG 1 ATOM 5451 C CD1 . LEU B 1 178 ? -58.638 -2.125 273.787 1.00 20.39 ? 178 LEU B CD1 1 ATOM 5452 C CD2 . LEU B 1 178 ? -60.359 -0.975 272.388 1.00 25.12 ? 178 LEU B CD2 1 ATOM 5453 N N . TYR B 1 179 ? -64.478 -3.544 273.590 1.00 21.23 ? 179 TYR B N 1 ATOM 5454 C CA . TYR B 1 179 ? -65.515 -4.540 273.843 1.00 20.38 ? 179 TYR B CA 1 ATOM 5455 C C . TYR B 1 179 ? -65.048 -5.892 273.314 1.00 20.48 ? 179 TYR B C 1 ATOM 5456 O O . TYR B 1 179 ? -64.952 -6.093 272.100 1.00 21.11 ? 179 TYR B O 1 ATOM 5457 C CB . TYR B 1 179 ? -66.830 -4.121 273.191 1.00 19.13 ? 179 TYR B CB 1 ATOM 5458 C CG . TYR B 1 179 ? -67.972 -5.078 273.446 1.00 22.37 ? 179 TYR B CG 1 ATOM 5459 C CD1 . TYR B 1 179 ? -68.730 -4.992 274.605 1.00 21.64 ? 179 TYR B CD1 1 ATOM 5460 C CD2 . TYR B 1 179 ? -68.293 -6.067 272.525 1.00 22.98 ? 179 TYR B CD2 1 ATOM 5461 C CE1 . TYR B 1 179 ? -69.774 -5.864 274.841 1.00 19.77 ? 179 TYR B CE1 1 ATOM 5462 C CE2 . TYR B 1 179 ? -69.334 -6.943 272.752 1.00 18.65 ? 179 TYR B CE2 1 ATOM 5463 C CZ . TYR B 1 179 ? -70.071 -6.837 273.912 1.00 17.98 ? 179 TYR B CZ 1 ATOM 5464 O OH . TYR B 1 179 ? -71.110 -7.707 274.141 1.00 21.08 ? 179 TYR B OH 1 ATOM 5465 N N . GLY B 1 180 ? -64.773 -6.819 274.225 1.00 19.74 ? 180 GLY B N 1 ATOM 5466 C CA . GLY B 1 180 ? -64.353 -8.155 273.847 1.00 20.17 ? 180 GLY B CA 1 ATOM 5467 C C . GLY B 1 180 ? -65.313 -9.234 274.309 1.00 19.83 ? 180 GLY B C 1 ATOM 5468 O O . GLY B 1 180 ? -65.769 -9.217 275.453 1.00 17.13 ? 180 GLY B O 1 ATOM 5469 N N . PHE B 1 181 ? -65.620 -10.178 273.423 1.00 21.70 ? 181 PHE B N 1 ATOM 5470 C CA . PHE B 1 181 ? -65.054 -10.200 272.078 1.00 21.43 ? 181 PHE B CA 1 ATOM 5471 C C . PHE B 1 181 ? -66.129 -10.403 271.016 1.00 21.19 ? 181 PHE B C 1 ATOM 5472 O O . PHE B 1 181 ? -67.163 -11.014 271.277 1.00 19.35 ? 181 PHE B O 1 ATOM 5473 C CB . PHE B 1 181 ? -64.000 -11.302 271.960 1.00 18.58 ? 181 PHE B CB 1 ATOM 5474 C CG . PHE B 1 181 ? -62.785 -11.074 272.810 1.00 20.04 ? 181 PHE B CG 1 ATOM 5475 C CD1 . PHE B 1 181 ? -61.820 -10.157 272.430 1.00 20.13 ? 181 PHE B CD1 1 ATOM 5476 C CD2 . PHE B 1 181 ? -62.605 -11.778 273.989 1.00 21.04 ? 181 PHE B CD2 1 ATOM 5477 C CE1 . PHE B 1 181 ? -60.701 -9.945 273.209 1.00 20.26 ? 181 PHE B CE1 1 ATOM 5478 C CE2 . PHE B 1 181 ? -61.487 -11.570 274.773 1.00 19.28 ? 181 PHE B CE2 1 ATOM 5479 C CZ . PHE B 1 181 ? -60.534 -10.653 274.381 1.00 20.57 ? 181 PHE B CZ 1 ATOM 5480 N N . ILE B 1 182 ? -65.876 -9.890 269.815 1.00 23.64 ? 182 ILE B N 1 ATOM 5481 C CA . ILE B 1 182 ? -66.766 -10.079 268.675 1.00 22.52 ? 182 ILE B CA 1 ATOM 5482 C C . ILE B 1 182 ? -66.267 -11.296 267.896 1.00 21.53 ? 182 ILE B C 1 ATOM 5483 O O . ILE B 1 182 ? -65.186 -11.221 267.288 1.00 20.40 ? 182 ILE B O 1 ATOM 5484 C CB . ILE B 1 182 ? -66.815 -8.833 267.784 1.00 22.08 ? 182 ILE B CB 1 ATOM 5485 C CG1 . ILE B 1 182 ? -67.449 -7.668 268.543 1.00 24.85 ? 182 ILE B CG1 1 ATOM 5486 C CG2 . ILE B 1 182 ? -67.583 -9.121 266.505 1.00 22.15 ? 182 ILE B CG2 1 ATOM 5487 C CD1 . ILE B 1 182 ? -68.820 -7.980 269.094 1.00 20.66 ? 182 ILE B CD1 1 ATOM 5488 N N . PRO B 1 183 ? -66.999 -12.403 267.883 1.00 24.16 ? 183 PRO B N 1 ATOM 5489 C CA . PRO B 1 183 ? -66.478 -13.635 267.286 1.00 26.82 ? 183 PRO B CA 1 ATOM 5490 C C . PRO B 1 183 ? -66.568 -13.616 265.766 1.00 30.50 ? 183 PRO B C 1 ATOM 5491 O O . PRO B 1 183 ? -67.105 -12.696 265.150 1.00 29.31 ? 183 PRO B O 1 ATOM 5492 C CB . PRO B 1 183 ? -67.393 -14.711 267.874 1.00 25.46 ? 183 PRO B CB 1 ATOM 5493 C CG . PRO B 1 183 ? -68.683 -14.010 268.049 1.00 26.12 ? 183 PRO B CG 1 ATOM 5494 C CD . PRO B 1 183 ? -68.340 -12.600 268.459 1.00 25.30 ? 183 PRO B CD 1 ATOM 5495 N N . ILE B 1 184 ? -66.020 -14.671 265.171 1.00 34.46 ? 184 ILE B N 1 ATOM 5496 C CA . ILE B 1 184 ? -66.058 -14.899 263.733 1.00 32.75 ? 184 ILE B CA 1 ATOM 5497 C C . ILE B 1 184 ? -66.706 -16.255 263.495 1.00 32.61 ? 184 ILE B C 1 ATOM 5498 O O . ILE B 1 184 ? -66.286 -17.258 264.083 1.00 34.49 ? 184 ILE B O 1 ATOM 5499 C CB . ILE B 1 184 ? -64.650 -14.847 263.112 1.00 32.25 ? 184 ILE B CB 1 ATOM 5500 C CG1 . ILE B 1 184 ? -63.951 -13.538 263.481 1.00 30.15 ? 184 ILE B CG1 1 ATOM 5501 C CG2 . ILE B 1 184 ? -64.732 -14.989 261.609 1.00 35.07 ? 184 ILE B CG2 1 ATOM 5502 C CD1 . ILE B 1 184 ? -62.564 -13.405 262.895 1.00 28.76 ? 184 ILE B CD1 1 ATOM 5503 N N . CYS B 1 185 ? -67.725 -16.281 262.640 1.00 35.07 ? 185 CYS B N 1 ATOM 5504 C CA . CYS B 1 185 ? -68.502 -17.494 262.429 1.00 36.37 ? 185 CYS B CA 1 ATOM 5505 C C . CYS B 1 185 ? -67.652 -18.594 261.801 1.00 37.30 ? 185 CYS B C 1 ATOM 5506 O O . CYS B 1 185 ? -66.741 -18.337 261.010 1.00 39.20 ? 185 CYS B O 1 ATOM 5507 C CB . CYS B 1 185 ? -69.714 -17.204 261.544 1.00 39.74 ? 185 CYS B CB 1 ATOM 5508 S SG . CYS B 1 185 ? -71.023 -16.237 262.338 1.00 46.00 ? 185 CYS B SG 1 ATOM 5509 N N . GLY B 1 186 ? -67.967 -19.835 262.166 1.00 37.45 ? 186 GLY B N 1 ATOM 5510 C CA . GLY B 1 186 ? -67.249 -20.992 261.668 1.00 38.03 ? 186 GLY B CA 1 ATOM 5511 C C . GLY B 1 186 ? -67.548 -22.248 262.461 1.00 37.03 ? 186 GLY B C 1 ATOM 5512 O O . GLY B 1 186 ? -67.764 -22.184 263.675 1.00 34.51 ? 186 GLY B O 1 ATOM 5513 N N . GLY B 1 187 ? -67.562 -23.391 261.791 1.00 44.24 ? 187 GLY B N 1 ATOM 5514 C CA . GLY B 1 187 ? -67.867 -24.673 262.410 1.00 39.79 ? 187 GLY B CA 1 ATOM 5515 C C . GLY B 1 187 ? -66.620 -25.416 262.838 1.00 30.29 ? 187 GLY B C 1 ATOM 5516 O O . GLY B 1 187 ? -65.673 -24.827 263.372 1.00 32.45 ? 187 GLY B O 1 ATOM 5517 N N . ASP B 1 188 ? -66.620 -26.727 262.608 1.00 25.97 ? 188 ASP B N 1 ATOM 5518 C CA . ASP B 1 188 ? -65.466 -27.547 262.947 1.00 26.66 ? 188 ASP B CA 1 ATOM 5519 C C . ASP B 1 188 ? -64.281 -27.192 262.061 1.00 28.10 ? 188 ASP B C 1 ATOM 5520 O O . ASP B 1 188 ? -64.424 -27.002 260.850 1.00 39.94 ? 188 ASP B O 1 ATOM 5521 C CB . ASP B 1 188 ? -65.803 -29.031 262.801 1.00 29.55 ? 188 ASP B CB 1 ATOM 5522 C CG . ASP B 1 188 ? -66.796 -29.508 263.840 1.00 31.26 ? 188 ASP B CG 1 ATOM 5523 O OD1 . ASP B 1 188 ? -66.690 -29.078 265.007 1.00 44.56 ? 188 ASP B OD1 1 ATOM 5524 O OD2 . ASP B 1 188 ? -67.683 -30.314 263.489 1.00 33.52 ? 188 ASP B OD2 1 ATOM 5525 N N . GLY B 1 189 ? -63.101 -27.105 262.673 1.00 28.78 ? 189 GLY B N 1 ATOM 5526 C CA . GLY B 1 189 ? -61.901 -26.709 261.973 1.00 30.02 ? 189 GLY B CA 1 ATOM 5527 C C . GLY B 1 189 ? -61.696 -25.217 261.843 1.00 28.80 ? 189 GLY B C 1 ATOM 5528 O O . GLY B 1 189 ? -60.578 -24.785 261.540 1.00 29.08 ? 189 GLY B O 1 ATOM 5529 N N . ILE B 1 190 ? -62.734 -24.412 262.061 1.00 30.28 ? 190 ILE B N 1 ATOM 5530 C CA . ILE B 1 190 ? -62.607 -22.962 261.981 1.00 28.94 ? 190 ILE B CA 1 ATOM 5531 C C . ILE B 1 190 ? -62.557 -22.305 263.359 1.00 28.53 ? 190 ILE B C 1 ATOM 5532 O O . ILE B 1 190 ? -62.008 -21.201 263.485 1.00 29.47 ? 190 ILE B O 1 ATOM 5533 C CB . ILE B 1 190 ? -63.753 -22.363 261.138 1.00 29.55 ? 190 ILE B CB 1 ATOM 5534 C CG1 . ILE B 1 190 ? -63.961 -23.190 259.868 1.00 33.26 ? 190 ILE B CG1 1 ATOM 5535 C CG2 . ILE B 1 190 ? -63.461 -20.916 260.769 1.00 33.63 ? 190 ILE B CG2 1 ATOM 5536 C CD1 . ILE B 1 190 ? -65.102 -22.709 259.001 1.00 51.15 ? 190 ILE B CD1 1 ATOM 5537 N N . ASN B 1 191 ? -63.097 -22.950 264.389 1.00 28.84 ? 191 ASN B N 1 ATOM 5538 C CA . ASN B 1 191 ? -63.089 -22.422 265.751 1.00 30.26 ? 191 ASN B CA 1 ATOM 5539 C C . ASN B 1 191 ? -62.924 -23.562 266.748 1.00 28.17 ? 191 ASN B C 1 ATOM 5540 O O . ASN B 1 191 ? -63.661 -23.675 267.728 1.00 28.18 ? 191 ASN B O 1 ATOM 5541 C CB . ASN B 1 191 ? -64.361 -21.629 266.043 1.00 30.23 ? 191 ASN B CB 1 ATOM 5542 C CG . ASN B 1 191 ? -64.337 -20.246 265.431 1.00 32.61 ? 191 ASN B CG 1 ATOM 5543 O OD1 . ASN B 1 191 ? -63.645 -19.353 265.917 1.00 33.13 ? 191 ASN B OD1 1 ATOM 5544 N ND2 . ASN B 1 191 ? -65.094 -20.062 264.358 1.00 44.11 ? 191 ASN B ND2 1 ATOM 5545 N N . ASP B 1 192 ? -61.940 -24.429 266.498 1.00 29.17 ? 192 ASP B N 1 ATOM 5546 C CA . ASP B 1 192 ? -61.696 -25.559 267.387 1.00 32.44 ? 192 ASP B CA 1 ATOM 5547 C C . ASP B 1 192 ? -61.169 -25.128 268.750 1.00 29.81 ? 192 ASP B C 1 ATOM 5548 O O . ASP B 1 192 ? -61.251 -25.908 269.705 1.00 27.16 ? 192 ASP B O 1 ATOM 5549 C CB . ASP B 1 192 ? -60.714 -26.540 266.742 1.00 41.00 ? 192 ASP B CB 1 ATOM 5550 C CG . ASP B 1 192 ? -61.252 -27.153 265.463 1.00 34.21 ? 192 ASP B CG 1 ATOM 5551 O OD1 . ASP B 1 192 ? -62.485 -27.138 265.264 1.00 27.39 ? 192 ASP B OD1 1 ATOM 5552 O OD2 . ASP B 1 192 ? -60.441 -27.661 264.662 1.00 36.19 ? 192 ASP B OD2 1 ATOM 5553 N N . ALA B 1 193 ? -60.627 -23.914 268.864 1.00 28.79 ? 193 ALA B N 1 ATOM 5554 C CA . ALA B 1 193 ? -60.155 -23.435 270.158 1.00 25.70 ? 193 ALA B CA 1 ATOM 5555 C C . ALA B 1 193 ? -61.300 -23.156 271.121 1.00 25.14 ? 193 ALA B C 1 ATOM 5556 O O . ALA B 1 193 ? -61.074 -23.104 272.334 1.00 26.96 ? 193 ALA B O 1 ATOM 5557 C CB . ALA B 1 193 ? -59.308 -22.175 269.982 1.00 23.71 ? 193 ALA B CB 1 ATOM 5558 N N . LEU B 1 194 ? -62.520 -22.977 270.610 1.00 24.88 ? 194 LEU B N 1 ATOM 5559 C CA . LEU B 1 194 ? -63.663 -22.720 271.477 1.00 27.19 ? 194 LEU B CA 1 ATOM 5560 C C . LEU B 1 194 ? -64.108 -23.962 272.234 1.00 30.87 ? 194 LEU B C 1 ATOM 5561 O O . LEU B 1 194 ? -64.760 -23.836 273.276 1.00 46.10 ? 194 LEU B O 1 ATOM 5562 C CB . LEU B 1 194 ? -64.830 -22.170 270.658 1.00 27.53 ? 194 LEU B CB 1 ATOM 5563 C CG . LEU B 1 194 ? -64.748 -20.697 270.268 1.00 26.17 ? 194 LEU B CG 1 ATOM 5564 C CD1 . LEU B 1 194 ? -65.889 -20.345 269.335 1.00 28.01 ? 194 LEU B CD1 1 ATOM 5565 C CD2 . LEU B 1 194 ? -64.768 -19.814 271.504 1.00 26.38 ? 194 LEU B CD2 1 ATOM 5566 N N . LYS B 1 195 ? -63.775 -25.153 271.735 1.00 27.01 ? 195 LYS B N 1 ATOM 5567 C CA . LYS B 1 195 ? -64.157 -26.389 272.406 1.00 27.83 ? 195 LYS B CA 1 ATOM 5568 C C . LYS B 1 195 ? -63.448 -26.578 273.740 1.00 25.34 ? 195 LYS B C 1 ATOM 5569 O O . LYS B 1 195 ? -63.845 -27.457 274.513 1.00 23.56 ? 195 LYS B O 1 ATOM 5570 C CB . LYS B 1 195 ? -63.880 -27.582 271.489 1.00 30.89 ? 195 LYS B CB 1 ATOM 5571 C CG . LYS B 1 195 ? -64.582 -27.488 270.142 1.00 30.36 ? 195 LYS B CG 1 ATOM 5572 C CD . LYS B 1 195 ? -64.097 -28.557 269.177 1.00 42.08 ? 195 LYS B CD 1 ATOM 5573 C CE . LYS B 1 195 ? -64.890 -28.523 267.880 1.00 37.45 ? 195 LYS B CE 1 ATOM 5574 N NZ . LYS B 1 195 ? -64.352 -29.477 266.871 1.00 39.60 ? 195 LYS B NZ 1 ATOM 5575 N N . THR B 1 196 ? -62.416 -25.782 274.028 1.00 26.31 ? 196 THR B N 1 ATOM 5576 C CA . THR B 1 196 ? -61.764 -25.854 275.331 1.00 27.07 ? 196 THR B CA 1 ATOM 5577 C C . THR B 1 196 ? -62.688 -25.370 276.442 1.00 29.05 ? 196 THR B C 1 ATOM 5578 O O . THR B 1 196 ? -62.572 -25.823 277.586 1.00 31.90 ? 196 THR B O 1 ATOM 5579 C CB . THR B 1 196 ? -60.472 -25.035 275.313 1.00 27.94 ? 196 THR B CB 1 ATOM 5580 O OG1 . THR B 1 196 ? -59.696 -25.393 274.162 1.00 23.58 ? 196 THR B OG1 1 ATOM 5581 C CG2 . THR B 1 196 ? -59.648 -25.295 276.565 1.00 36.86 ? 196 THR B CG2 1 ATOM 5582 N N . ILE B 1 197 ? -63.611 -24.465 276.126 1.00 31.40 ? 197 ILE B N 1 ATOM 5583 C CA . ILE B 1 197 ? -64.577 -23.946 277.086 1.00 31.50 ? 197 ILE B CA 1 ATOM 5584 C C . ILE B 1 197 ? -65.911 -24.638 276.847 1.00 36.72 ? 197 ILE B C 1 ATOM 5585 O O . ILE B 1 197 ? -66.369 -24.742 275.702 1.00 48.52 ? 197 ILE B O 1 ATOM 5586 C CB . ILE B 1 197 ? -64.717 -22.419 276.965 1.00 31.89 ? 197 ILE B CB 1 ATOM 5587 C CG1 . ILE B 1 197 ? -63.343 -21.752 277.048 1.00 33.30 ? 197 ILE B CG1 1 ATOM 5588 C CG2 . ILE B 1 197 ? -65.638 -21.880 278.047 1.00 36.24 ? 197 ILE B CG2 1 ATOM 5589 C CD1 . ILE B 1 197 ? -63.385 -20.253 276.877 1.00 35.87 ? 197 ILE B CD1 1 ATOM 5590 N N . SER B 1 198 ? -66.534 -25.110 277.924 1.00 36.93 ? 198 SER B N 1 ATOM 5591 C CA . SER B 1 198 ? -67.773 -25.866 277.806 1.00 46.76 ? 198 SER B CA 1 ATOM 5592 C C . SER B 1 198 ? -68.909 -24.967 277.333 1.00 35.53 ? 198 SER B C 1 ATOM 5593 O O . SER B 1 198 ? -69.145 -23.894 277.896 1.00 34.50 ? 198 SER B O 1 ATOM 5594 C CB . SER B 1 198 ? -68.129 -26.506 279.147 1.00 45.56 ? 198 SER B CB 1 ATOM 5595 O OG . SER B 1 198 ? -66.979 -27.056 279.767 1.00 51.61 ? 198 SER B OG 1 ATOM 5596 N N . GLY B 1 199 ? -69.613 -25.409 276.291 1.00 36.02 ? 199 GLY B N 1 ATOM 5597 C CA . GLY B 1 199 ? -70.724 -24.664 275.739 1.00 32.42 ? 199 GLY B CA 1 ATOM 5598 C C . GLY B 1 199 ? -70.356 -23.427 274.952 1.00 32.11 ? 199 GLY B C 1 ATOM 5599 O O . GLY B 1 199 ? -71.245 -22.814 274.350 1.00 31.06 ? 199 GLY B O 1 ATOM 5600 N N . SER B 1 200 ? -69.080 -23.035 274.931 1.00 34.26 ? 200 SER B N 1 ATOM 5601 C CA . SER B 1 200 ? -68.690 -21.838 274.194 1.00 31.79 ? 200 SER B CA 1 ATOM 5602 C C . SER B 1 200 ? -68.731 -22.075 272.691 1.00 29.80 ? 200 SER B C 1 ATOM 5603 O O . SER B 1 200 ? -69.216 -21.224 271.936 1.00 27.47 ? 200 SER B O 1 ATOM 5604 C CB . SER B 1 200 ? -67.297 -21.386 274.629 1.00 30.51 ? 200 SER B CB 1 ATOM 5605 O OG . SER B 1 200 ? -66.897 -20.224 273.927 1.00 31.69 ? 200 SER B OG 1 ATOM 5606 N N . PHE B 1 201 ? -68.223 -23.223 272.236 1.00 30.91 ? 201 PHE B N 1 ATOM 5607 C CA . PHE B 1 201 ? -68.274 -23.536 270.811 1.00 31.69 ? 201 PHE B CA 1 ATOM 5608 C C . PHE B 1 201 ? -69.712 -23.707 270.340 1.00 33.59 ? 201 PHE B C 1 ATOM 5609 O O . PHE B 1 201 ? -70.065 -23.286 269.232 1.00 42.92 ? 201 PHE B O 1 ATOM 5610 C CB . PHE B 1 201 ? -67.458 -24.796 270.519 1.00 28.24 ? 201 PHE B CB 1 ATOM 5611 C CG . PHE B 1 201 ? -67.502 -25.230 269.079 1.00 32.60 ? 201 PHE B CG 1 ATOM 5612 C CD1 . PHE B 1 201 ? -66.651 -24.664 268.145 1.00 31.85 ? 201 PHE B CD1 1 ATOM 5613 C CD2 . PHE B 1 201 ? -68.391 -26.208 268.662 1.00 32.75 ? 201 PHE B CD2 1 ATOM 5614 C CE1 . PHE B 1 201 ? -66.689 -25.061 266.821 1.00 29.92 ? 201 PHE B CE1 1 ATOM 5615 C CE2 . PHE B 1 201 ? -68.433 -26.607 267.339 1.00 29.98 ? 201 PHE B CE2 1 ATOM 5616 C CZ . PHE B 1 201 ? -67.581 -26.033 266.419 1.00 27.16 ? 201 PHE B CZ 1 ATOM 5617 N N . GLU B 1 202 ? -70.558 -24.319 271.172 1.00 40.11 ? 202 GLU B N 1 ATOM 5618 C CA . GLU B 1 202 ? -71.953 -24.518 270.794 1.00 33.36 ? 202 GLU B CA 1 ATOM 5619 C C . GLU B 1 202 ? -72.709 -23.198 270.726 1.00 31.41 ? 202 GLU B C 1 ATOM 5620 O O . GLU B 1 202 ? -73.622 -23.051 269.905 1.00 32.63 ? 202 GLU B O 1 ATOM 5621 C CB . GLU B 1 202 ? -72.641 -25.466 271.778 1.00 35.98 ? 202 GLU B CB 1 ATOM 5622 C CG . GLU B 1 202 ? -72.037 -26.865 271.859 1.00 40.42 ? 202 GLU B CG 1 ATOM 5623 C CD . GLU B 1 202 ? -70.783 -26.923 272.714 1.00 34.07 ? 202 GLU B CD 1 ATOM 5624 O OE1 . GLU B 1 202 ? -69.749 -26.355 272.302 1.00 35.35 ? 202 GLU B OE1 1 ATOM 5625 O OE2 . GLU B 1 202 ? -70.832 -27.534 273.801 1.00 34.25 ? 202 GLU B OE2 1 ATOM 5626 N N . SER B 1 203 ? -72.347 -22.233 271.575 1.00 35.79 ? 203 SER B N 1 ATOM 5627 C CA . SER B 1 203 ? -73.047 -20.953 271.583 1.00 30.05 ? 203 SER B CA 1 ATOM 5628 C C . SER B 1 203 ? -72.800 -20.176 270.296 1.00 27.91 ? 203 SER B C 1 ATOM 5629 O O . SER B 1 203 ? -73.716 -19.538 269.765 1.00 28.77 ? 203 SER B O 1 ATOM 5630 C CB . SER B 1 203 ? -72.621 -20.128 272.796 1.00 31.21 ? 203 SER B CB 1 ATOM 5631 O OG . SER B 1 203 ? -72.863 -20.833 274.001 1.00 52.48 ? 203 SER B OG 1 ATOM 5632 N N . LEU B 1 204 ? -71.569 -20.216 269.779 1.00 30.87 ? 204 LEU B N 1 ATOM 5633 C CA . LEU B 1 204 ? -71.277 -19.511 268.536 1.00 27.83 ? 204 LEU B CA 1 ATOM 5634 C C . LEU B 1 204 ? -72.005 -20.145 267.358 1.00 29.04 ? 204 LEU B C 1 ATOM 5635 O O . LEU B 1 204 ? -72.515 -19.436 266.484 1.00 29.79 ? 204 LEU B O 1 ATOM 5636 C CB . LEU B 1 204 ? -69.771 -19.484 268.282 1.00 27.97 ? 204 LEU B CB 1 ATOM 5637 C CG . LEU B 1 204 ? -69.374 -18.708 267.026 1.00 30.51 ? 204 LEU B CG 1 ATOM 5638 C CD1 . LEU B 1 204 ? -69.859 -17.275 267.132 1.00 32.57 ? 204 LEU B CD1 1 ATOM 5639 C CD2 . LEU B 1 204 ? -67.875 -18.754 266.793 1.00 58.76 ? 204 LEU B CD2 1 ATOM 5640 N N . GLN B 1 205 ? -72.060 -21.478 267.316 1.00 31.35 ? 205 GLN B N 1 ATOM 5641 C CA . GLN B 1 205 ? -72.815 -22.156 266.267 1.00 31.57 ? 205 GLN B CA 1 ATOM 5642 C C . GLN B 1 205 ? -74.292 -21.794 266.343 1.00 29.91 ? 205 GLN B C 1 ATOM 5643 O O . GLN B 1 205 ? -74.924 -21.493 265.324 1.00 28.23 ? 205 GLN B O 1 ATOM 5644 C CB . GLN B 1 205 ? -72.625 -23.670 266.377 1.00 34.20 ? 205 GLN B CB 1 ATOM 5645 C CG . GLN B 1 205 ? -71.176 -24.126 266.346 1.00 41.28 ? 205 GLN B CG 1 ATOM 5646 C CD . GLN B 1 205 ? -70.442 -23.655 265.108 1.00 44.78 ? 205 GLN B CD 1 ATOM 5647 O OE1 . GLN B 1 205 ? -70.941 -23.784 263.990 1.00 37.09 ? 205 GLN B OE1 1 ATOM 5648 N NE2 . GLN B 1 205 ? -69.248 -23.107 265.300 1.00 42.83 ? 205 GLN B NE2 1 ATOM 5649 N N . ARG B 1 206 ? -74.859 -21.815 267.552 1.00 29.75 ? 206 ARG B N 1 ATOM 5650 C CA . ARG B 1 206 ? -76.247 -21.403 267.725 1.00 29.14 ? 206 ARG B CA 1 ATOM 5651 C C . ARG B 1 206 ? -76.430 -19.926 267.405 1.00 28.03 ? 206 ARG B C 1 ATOM 5652 O O . ARG B 1 206 ? -77.527 -19.503 267.023 1.00 36.71 ? 206 ARG B O 1 ATOM 5653 C CB . ARG B 1 206 ? -76.705 -21.711 269.151 1.00 32.76 ? 206 ARG B CB 1 ATOM 5654 C CG . ARG B 1 206 ? -78.203 -21.584 269.373 1.00 40.50 ? 206 ARG B CG 1 ATOM 5655 C CD . ARG B 1 206 ? -78.618 -22.150 270.724 1.00 38.34 ? 206 ARG B CD 1 ATOM 5656 N NE . ARG B 1 206 ? -78.063 -21.394 271.844 1.00 52.94 ? 206 ARG B NE 1 ATOM 5657 C CZ . ARG B 1 206 ? -77.031 -21.794 272.580 1.00 58.59 ? 206 ARG B CZ 1 ATOM 5658 N NH1 . ARG B 1 206 ? -76.433 -22.949 272.317 1.00 49.99 ? 206 ARG B NH1 1 ATOM 5659 N NH2 . ARG B 1 206 ? -76.595 -21.041 273.581 1.00 49.01 ? 206 ARG B NH2 1 ATOM 5660 N N . SER B 1 207 ? -75.370 -19.128 267.547 1.00 25.90 ? 207 SER B N 1 ATOM 5661 C CA . SER B 1 207 ? -75.438 -17.723 267.168 1.00 26.42 ? 207 SER B CA 1 ATOM 5662 C C . SER B 1 207 ? -75.185 -17.523 265.679 1.00 25.98 ? 207 SER B C 1 ATOM 5663 O O . SER B 1 207 ? -75.692 -16.560 265.093 1.00 25.49 ? 207 SER B O 1 ATOM 5664 C CB . SER B 1 207 ? -74.436 -16.908 267.986 1.00 31.23 ? 207 SER B CB 1 ATOM 5665 O OG . SER B 1 207 ? -74.452 -15.545 267.602 1.00 51.68 ? 207 SER B OG 1 ATOM 5666 N N . CYS B 1 208 ? -74.410 -18.411 265.055 1.00 28.71 ? 208 CYS B N 1 ATOM 5667 C CA . CYS B 1 208 ? -74.117 -18.343 263.628 1.00 35.62 ? 208 CYS B CA 1 ATOM 5668 C C . CYS B 1 208 ? -74.949 -19.330 262.816 1.00 27.21 ? 208 CYS B C 1 ATOM 5669 O O . CYS B 1 208 ? -74.521 -19.756 261.737 1.00 37.49 ? 208 CYS B O 1 ATOM 5670 C CB . CYS B 1 208 ? -72.629 -18.585 263.371 1.00 38.32 ? 208 CYS B CB 1 ATOM 5671 S SG . CYS B 1 208 ? -71.504 -17.315 263.993 1.00 31.09 ? 208 CYS B SG 1 ATOM 5672 N N . LYS B 1 209 ? -76.125 -19.709 263.310 1.00 24.01 ? 209 LYS B N 1 ATOM 5673 C CA . LYS B 1 209 ? -76.966 -20.647 262.577 1.00 24.55 ? 209 LYS B CA 1 ATOM 5674 C C . LYS B 1 209 ? -77.460 -20.004 261.288 1.00 24.15 ? 209 LYS B C 1 ATOM 5675 O O . LYS B 1 209 ? -77.990 -18.888 261.301 1.00 20.46 ? 209 LYS B O 1 ATOM 5676 C CB . LYS B 1 209 ? -78.148 -21.097 263.434 1.00 22.97 ? 209 LYS B CB 1 ATOM 5677 C CG . LYS B 1 209 ? -78.631 -22.500 263.104 1.00 22.13 ? 209 LYS B CG 1 ATOM 5678 C CD . LYS B 1 209 ? -79.782 -22.929 263.996 1.00 27.15 ? 209 LYS B CD 1 ATOM 5679 C CE . LYS B 1 209 ? -81.117 -22.480 263.425 1.00 43.05 ? 209 LYS B CE 1 ATOM 5680 N NZ . LYS B 1 209 ? -82.263 -23.154 264.095 1.00 24.40 ? 209 LYS B NZ 1 ATOM 5681 N N . GLY B 1 210 ? -77.275 -20.706 260.171 1.00 28.61 ? 210 GLY B N 1 ATOM 5682 C CA . GLY B 1 210 ? -77.609 -20.177 258.866 1.00 28.83 ? 210 GLY B CA 1 ATOM 5683 C C . GLY B 1 210 ? -76.683 -19.097 258.355 1.00 28.11 ? 210 GLY B C 1 ATOM 5684 O O . GLY B 1 210 ? -76.743 -18.770 257.163 1.00 30.48 ? 210 GLY B O 1 ATOM 5685 N N . ARG B 1 211 ? -75.832 -18.533 259.207 1.00 29.31 ? 211 ARG B N 1 ATOM 5686 C CA . ARG B 1 211 ? -74.901 -17.489 258.808 1.00 32.29 ? 211 ARG B CA 1 ATOM 5687 C C . ARG B 1 211 ? -73.617 -18.127 258.297 1.00 30.46 ? 211 ARG B C 1 ATOM 5688 O O . ARG B 1 211 ? -73.175 -19.157 258.813 1.00 31.82 ? 211 ARG B O 1 ATOM 5689 C CB . ARG B 1 211 ? -74.609 -16.564 259.989 1.00 33.57 ? 211 ARG B CB 1 ATOM 5690 C CG . ARG B 1 211 ? -74.194 -15.156 259.609 1.00 36.39 ? 211 ARG B CG 1 ATOM 5691 C CD . ARG B 1 211 ? -73.704 -14.395 260.832 1.00 36.63 ? 211 ARG B CD 1 ATOM 5692 N NE . ARG B 1 211 ? -73.764 -12.947 260.649 1.00 37.14 ? 211 ARG B NE 1 ATOM 5693 C CZ . ARG B 1 211 ? -72.943 -12.249 259.872 1.00 40.40 ? 211 ARG B CZ 1 ATOM 5694 N NH1 . ARG B 1 211 ? -71.984 -12.858 259.191 1.00 42.65 ? 211 ARG B NH1 1 ATOM 5695 N NH2 . ARG B 1 211 ? -73.083 -10.935 259.775 1.00 40.42 ? 211 ARG B NH2 1 ATOM 5696 N N . GLU B 1 212 ? -73.022 -17.514 257.280 1.00 34.20 ? 212 GLU B N 1 ATOM 5697 C CA . GLU B 1 212 ? -71.904 -18.142 256.595 1.00 41.85 ? 212 GLU B CA 1 ATOM 5698 C C . GLU B 1 212 ? -70.580 -17.796 257.272 1.00 47.03 ? 212 GLU B C 1 ATOM 5699 O O . GLU B 1 212 ? -70.477 -16.845 258.051 1.00 49.32 ? 212 GLU B O 1 ATOM 5700 C CB . GLU B 1 212 ? -71.886 -17.744 255.120 1.00 47.36 ? 212 GLU B CB 1 ATOM 5701 C CG . GLU B 1 212 ? -72.546 -18.790 254.230 1.00 63.21 ? 212 GLU B CG 1 ATOM 5702 C CD . GLU B 1 212 ? -71.985 -18.822 252.824 1.00 64.64 ? 212 GLU B CD 1 ATOM 5703 O OE1 . GLU B 1 212 ? -71.082 -18.016 252.522 1.00 65.59 ? 212 GLU B OE1 1 ATOM 5704 O OE2 . GLU B 1 212 ? -72.452 -19.657 252.020 1.00 56.46 ? 212 GLU B OE2 1 ATOM 5705 N N . ASP B 1 213 ? -69.560 -18.588 256.953 1.00 62.76 ? 213 ASP B N 1 ATOM 5706 C CA . ASP B 1 213 ? -68.335 -18.661 257.734 1.00 55.08 ? 213 ASP B CA 1 ATOM 5707 C C . ASP B 1 213 ? -67.437 -17.447 257.496 1.00 51.39 ? 213 ASP B C 1 ATOM 5708 O O . ASP B 1 213 ? -67.639 -16.652 256.574 1.00 60.36 ? 213 ASP B O 1 ATOM 5709 C CB . ASP B 1 213 ? -67.576 -19.944 257.400 1.00 57.27 ? 213 ASP B CB 1 ATOM 5710 C CG . ASP B 1 213 ? -68.430 -21.183 257.567 1.00 56.64 ? 213 ASP B CG 1 ATOM 5711 O OD1 . ASP B 1 213 ? -69.219 -21.486 256.648 1.00 63.58 ? 213 ASP B OD1 1 ATOM 5712 O OD2 . ASP B 1 213 ? -68.313 -21.854 258.613 1.00 51.43 ? 213 ASP B OD2 1 ATOM 5713 N N . PHE B 1 214 ? -66.423 -17.323 258.359 1.00 46.54 ? 214 PHE B N 1 ATOM 5714 C CA . PHE B 1 214 ? -65.405 -16.275 258.266 1.00 47.09 ? 214 PHE B CA 1 ATOM 5715 C C . PHE B 1 214 ? -66.032 -14.885 258.271 1.00 44.26 ? 214 PHE B C 1 ATOM 5716 O O . PHE B 1 214 ? -65.627 -13.998 257.518 1.00 45.64 ? 214 PHE B O 1 ATOM 5717 C CB . PHE B 1 214 ? -64.520 -16.469 257.034 1.00 49.81 ? 214 PHE B CB 1 ATOM 5718 C CG . PHE B 1 214 ? -63.693 -17.717 257.081 1.00 64.05 ? 214 PHE B CG 1 ATOM 5719 C CD1 . PHE B 1 214 ? -62.479 -17.733 257.744 1.00 47.74 ? 214 PHE B CD1 1 ATOM 5720 C CD2 . PHE B 1 214 ? -64.134 -18.877 256.467 1.00 76.30 ? 214 PHE B CD2 1 ATOM 5721 C CE1 . PHE B 1 214 ? -61.719 -18.883 257.792 1.00 46.47 ? 214 PHE B CE1 1 ATOM 5722 C CE2 . PHE B 1 214 ? -63.377 -20.030 256.511 1.00 61.04 ? 214 PHE B CE2 1 ATOM 5723 C CZ . PHE B 1 214 ? -62.168 -20.034 257.173 1.00 59.38 ? 214 PHE B CZ 1 ATOM 5724 N N . LYS B 1 215 ? -67.022 -14.692 259.138 1.00 51.55 ? 215 LYS B N 1 ATOM 5725 C CA . LYS B 1 215 ? -67.776 -13.450 259.177 1.00 43.99 ? 215 LYS B CA 1 ATOM 5726 C C . LYS B 1 215 ? -68.191 -13.161 260.612 1.00 39.17 ? 215 LYS B C 1 ATOM 5727 O O . LYS B 1 215 ? -68.553 -14.076 261.358 1.00 64.26 ? 215 LYS B O 1 ATOM 5728 C CB . LYS B 1 215 ? -68.994 -13.529 258.256 1.00 43.96 ? 215 LYS B CB 1 ATOM 5729 C CG . LYS B 1 215 ? -68.875 -12.673 257.014 1.00 50.04 ? 215 LYS B CG 1 ATOM 5730 C CD . LYS B 1 215 ? -69.424 -11.296 257.282 1.00 67.10 ? 215 LYS B CD 1 ATOM 5731 C CE . LYS B 1 215 ? -69.482 -10.456 256.024 1.00 71.76 ? 215 LYS B CE 1 ATOM 5732 N NZ . LYS B 1 215 ? -68.161 -9.884 255.712 1.00 49.32 ? 215 LYS B NZ 1 ATOM 5733 N N . VAL B 1 216 ? -68.140 -11.882 260.991 1.00 33.91 ? 216 VAL B N 1 ATOM 5734 C CA . VAL B 1 216 ? -68.335 -11.515 262.386 1.00 33.23 ? 216 VAL B CA 1 ATOM 5735 C C . VAL B 1 216 ? -69.801 -11.662 262.771 1.00 36.89 ? 216 VAL B C 1 ATOM 5736 O O . VAL B 1 216 ? -70.707 -11.586 261.931 1.00 37.62 ? 216 VAL B O 1 ATOM 5737 C CB . VAL B 1 216 ? -67.839 -10.083 262.657 1.00 34.91 ? 216 VAL B CB 1 ATOM 5738 C CG1 . VAL B 1 216 ? -66.378 -9.943 262.274 1.00 34.13 ? 216 VAL B CG1 1 ATOM 5739 C CG2 . VAL B 1 216 ? -68.699 -9.073 261.919 1.00 42.89 ? 216 VAL B CG2 1 ATOM 5740 N N . ALA B 1 217 ? -70.031 -11.877 264.063 1.00 38.31 ? 217 ALA B N 1 ATOM 5741 C CA . ALA B 1 217 ? -71.373 -11.929 264.625 1.00 39.85 ? 217 ALA B CA 1 ATOM 5742 C C . ALA B 1 217 ? -71.314 -11.493 266.082 1.00 34.71 ? 217 ALA B C 1 ATOM 5743 O O . ALA B 1 217 ? -70.502 -10.637 266.444 1.00 41.30 ? 217 ALA B O 1 ATOM 5744 C CB . ALA B 1 217 ? -71.964 -13.334 264.497 1.00 41.51 ? 217 ALA B CB 1 ATOM 5745 N N . ILE B 1 218 ? -72.164 -12.071 266.925 1.00 31.66 ? 218 ILE B N 1 ATOM 5746 C CA . ILE B 1 218 ? -72.132 -11.829 268.361 1.00 29.43 ? 218 ILE B CA 1 ATOM 5747 C C . ILE B 1 218 ? -72.118 -13.176 269.066 1.00 30.12 ? 218 ILE B C 1 ATOM 5748 O O . ILE B 1 218 ? -72.932 -14.052 268.754 1.00 32.03 ? 218 ILE B O 1 ATOM 5749 C CB . ILE B 1 218 ? -73.324 -10.977 268.835 1.00 25.32 ? 218 ILE B CB 1 ATOM 5750 C CG1 . ILE B 1 218 ? -73.336 -9.627 268.115 1.00 24.23 ? 218 ILE B CG1 1 ATOM 5751 C CG2 . ILE B 1 218 ? -73.264 -10.776 270.337 1.00 24.74 ? 218 ILE B CG2 1 ATOM 5752 C CD1 . ILE B 1 218 ? -74.510 -8.750 268.482 1.00 25.60 ? 218 ILE B CD1 1 ATOM 5753 N N . HIS B 1 219 ? -71.190 -13.343 270.009 1.00 28.99 ? 219 HIS B N 1 ATOM 5754 C CA . HIS B 1 219 ? -71.058 -14.620 270.701 1.00 28.62 ? 219 HIS B CA 1 ATOM 5755 C C . HIS B 1 219 ? -72.279 -14.903 271.565 1.00 27.55 ? 219 HIS B C 1 ATOM 5756 O O . HIS B 1 219 ? -72.850 -15.999 271.514 1.00 25.03 ? 219 HIS B O 1 ATOM 5757 C CB . HIS B 1 219 ? -69.784 -14.624 271.546 1.00 26.80 ? 219 HIS B CB 1 ATOM 5758 C CG . HIS B 1 219 ? -69.266 -15.994 271.851 1.00 24.28 ? 219 HIS B CG 1 ATOM 5759 N ND1 . HIS B 1 219 ? -68.166 -16.211 272.653 1.00 24.03 ? 219 HIS B ND1 1 ATOM 5760 C CD2 . HIS B 1 219 ? -69.693 -17.217 271.459 1.00 24.68 ? 219 HIS B CD2 1 ATOM 5761 C CE1 . HIS B 1 219 ? -67.940 -17.510 272.744 1.00 32.23 ? 219 HIS B CE1 1 ATOM 5762 N NE2 . HIS B 1 219 ? -68.853 -18.142 272.029 1.00 26.46 ? 219 HIS B NE2 1 ATOM 5763 N N . ASP B 1 220 ? -72.697 -13.923 272.361 1.00 26.36 ? 220 ASP B N 1 ATOM 5764 C CA . ASP B 1 220 ? -73.850 -14.056 273.247 1.00 24.64 ? 220 ASP B CA 1 ATOM 5765 C C . ASP B 1 220 ? -74.765 -12.865 273.007 1.00 25.12 ? 220 ASP B C 1 ATOM 5766 O O . ASP B 1 220 ? -74.579 -11.794 273.603 1.00 40.12 ? 220 ASP B O 1 ATOM 5767 C CB . ASP B 1 220 ? -73.413 -14.145 274.707 1.00 24.74 ? 220 ASP B CB 1 ATOM 5768 C CG . ASP B 1 220 ? -74.581 -14.285 275.659 1.00 24.85 ? 220 ASP B CG 1 ATOM 5769 O OD1 . ASP B 1 220 ? -75.677 -14.678 275.211 1.00 24.93 ? 220 ASP B OD1 1 ATOM 5770 O OD2 . ASP B 1 220 ? -74.398 -14.003 276.860 1.00 23.09 ? 220 ASP B OD2 1 ATOM 5771 N N . PRO B 1 221 ? -75.770 -13.012 272.139 1.00 25.16 ? 221 PRO B N 1 ATOM 5772 C CA . PRO B 1 221 ? -76.680 -11.887 271.880 1.00 25.07 ? 221 PRO B CA 1 ATOM 5773 C C . PRO B 1 221 ? -77.541 -11.526 273.074 1.00 23.45 ? 221 PRO B C 1 ATOM 5774 O O . PRO B 1 221 ? -78.080 -10.413 273.112 1.00 20.82 ? 221 PRO B O 1 ATOM 5775 C CB . PRO B 1 221 ? -77.529 -12.393 270.709 1.00 24.63 ? 221 PRO B CB 1 ATOM 5776 C CG . PRO B 1 221 ? -77.579 -13.868 270.930 1.00 31.56 ? 221 PRO B CG 1 ATOM 5777 C CD . PRO B 1 221 ? -76.208 -14.239 271.452 1.00 26.23 ? 221 PRO B CD 1 ATOM 5778 N N . TRP B 1 222 ? -77.688 -12.427 274.045 1.00 26.49 ? 222 TRP B N 1 ATOM 5779 C CA . TRP B 1 222 ? -78.424 -12.101 275.261 1.00 25.03 ? 222 TRP B CA 1 ATOM 5780 C C . TRP B 1 222 ? -77.732 -10.991 276.041 1.00 23.61 ? 222 TRP B C 1 ATOM 5781 O O . TRP B 1 222 ? -78.299 -9.913 276.252 1.00 31.47 ? 222 TRP B O 1 ATOM 5782 C CB . TRP B 1 222 ? -78.586 -13.351 276.127 1.00 28.02 ? 222 TRP B CB 1 ATOM 5783 C CG . TRP B 1 222 ? -79.164 -13.043 277.461 1.00 26.60 ? 222 TRP B CG 1 ATOM 5784 C CD1 . TRP B 1 222 ? -78.527 -13.108 278.665 1.00 25.70 ? 222 TRP B CD1 1 ATOM 5785 C CD2 . TRP B 1 222 ? -80.482 -12.561 277.729 1.00 25.12 ? 222 TRP B CD2 1 ATOM 5786 N NE1 . TRP B 1 222 ? -79.378 -12.726 279.671 1.00 23.42 ? 222 TRP B NE1 1 ATOM 5787 C CE2 . TRP B 1 222 ? -80.585 -12.383 279.122 1.00 25.09 ? 222 TRP B CE2 1 ATOM 5788 C CE3 . TRP B 1 222 ? -81.591 -12.277 276.929 1.00 26.27 ? 222 TRP B CE3 1 ATOM 5789 C CZ2 . TRP B 1 222 ? -81.751 -11.931 279.730 1.00 29.52 ? 222 TRP B CZ2 1 ATOM 5790 C CZ3 . TRP B 1 222 ? -82.745 -11.827 277.533 1.00 33.25 ? 222 TRP B CZ3 1 ATOM 5791 C CH2 . TRP B 1 222 ? -82.816 -11.655 278.920 1.00 41.30 ? 222 TRP B CH2 1 ATOM 5792 N N . ALA B 1 223 ? -76.497 -11.239 276.480 1.00 21.84 ? 223 ALA B N 1 ATOM 5793 C CA . ALA B 1 223 ? -75.756 -10.230 277.225 1.00 23.00 ? 223 ALA B CA 1 ATOM 5794 C C . ALA B 1 223 ? -75.444 -9.003 276.382 1.00 22.80 ? 223 ALA B C 1 ATOM 5795 O O . ALA B 1 223 ? -75.211 -7.925 276.938 1.00 22.87 ? 223 ALA B O 1 ATOM 5796 C CB . ALA B 1 223 ? -74.460 -10.830 277.768 1.00 27.77 ? 223 ALA B CB 1 ATOM 5797 N N . ALA B 1 224 ? -75.448 -9.138 275.056 1.00 20.12 ? 224 ALA B N 1 ATOM 5798 C CA . ALA B 1 224 ? -75.040 -8.034 274.197 1.00 18.31 ? 224 ALA B CA 1 ATOM 5799 C C . ALA B 1 224 ? -76.154 -7.009 274.020 1.00 20.83 ? 224 ALA B C 1 ATOM 5800 O O . ALA B 1 224 ? -75.931 -5.807 274.201 1.00 26.07 ? 224 ALA B O 1 ATOM 5801 C CB . ALA B 1 224 ? -74.588 -8.567 272.838 1.00 20.22 ? 224 ALA B CB 1 ATOM 5802 N N . VAL B 1 225 ? -77.358 -7.457 273.666 1.00 19.21 ? 225 VAL B N 1 ATOM 5803 C CA . VAL B 1 225 ? -78.391 -6.526 273.227 1.00 16.52 ? 225 VAL B CA 1 ATOM 5804 C C . VAL B 1 225 ? -79.764 -6.911 273.766 1.00 19.03 ? 225 VAL B C 1 ATOM 5805 O O . VAL B 1 225 ? -80.728 -6.149 273.630 1.00 22.86 ? 225 VAL B O 1 ATOM 5806 C CB . VAL B 1 225 ? -78.410 -6.441 271.688 1.00 16.89 ? 225 VAL B CB 1 ATOM 5807 C CG1 . VAL B 1 225 ? -79.118 -7.650 271.094 1.00 20.49 ? 225 VAL B CG1 1 ATOM 5808 C CG2 . VAL B 1 225 ? -79.046 -5.138 271.220 1.00 20.62 ? 225 VAL B CG2 1 ATOM 5809 N N . GLN B 1 226 ? -79.873 -8.083 274.391 1.00 22.89 ? 226 GLN B N 1 ATOM 5810 C CA . GLN B 1 226 ? -81.173 -8.576 274.831 1.00 25.37 ? 226 GLN B CA 1 ATOM 5811 C C . GLN B 1 226 ? -81.395 -8.530 276.335 1.00 26.21 ? 226 GLN B C 1 ATOM 5812 O O . GLN B 1 226 ? -82.541 -8.382 276.765 1.00 24.86 ? 226 GLN B O 1 ATOM 5813 C CB . GLN B 1 226 ? -81.391 -10.017 274.354 1.00 22.55 ? 226 GLN B CB 1 ATOM 5814 C CG . GLN B 1 226 ? -81.493 -10.179 272.850 1.00 24.55 ? 226 GLN B CG 1 ATOM 5815 C CD . GLN B 1 226 ? -81.715 -11.622 272.443 1.00 27.12 ? 226 GLN B CD 1 ATOM 5816 O OE1 . GLN B 1 226 ? -81.504 -12.541 273.234 1.00 26.76 ? 226 GLN B OE1 1 ATOM 5817 N NE2 . GLN B 1 226 ? -82.152 -11.828 271.207 1.00 37.77 ? 226 GLN B NE2 1 ATOM 5818 N N . LYS B 1 227 ? -80.353 -8.657 277.145 1.00 26.00 ? 227 LYS B N 1 ATOM 5819 C CA . LYS B 1 227 ? -80.553 -8.744 278.589 1.00 25.92 ? 227 LYS B CA 1 ATOM 5820 C C . LYS B 1 227 ? -80.977 -7.388 279.144 1.00 29.73 ? 227 LYS B C 1 ATOM 5821 O O . LYS B 1 227 ? -80.337 -6.374 278.845 1.00 43.27 ? 227 LYS B O 1 ATOM 5822 C CB . LYS B 1 227 ? -79.284 -9.222 279.288 1.00 24.89 ? 227 LYS B CB 1 ATOM 5823 C CG . LYS B 1 227 ? -79.456 -9.411 280.788 1.00 24.23 ? 227 LYS B CG 1 ATOM 5824 C CD . LYS B 1 227 ? -78.216 -10.008 281.427 1.00 25.36 ? 227 LYS B CD 1 ATOM 5825 C CE . LYS B 1 227 ? -78.481 -10.392 282.874 1.00 30.70 ? 227 LYS B CE 1 ATOM 5826 N NZ . LYS B 1 227 ? -79.025 -9.253 283.663 1.00 31.31 ? 227 LYS B NZ 1 ATOM 5827 N N . PRO B 1 228 ? -82.042 -7.326 279.942 1.00 30.35 ? 228 PRO B N 1 ATOM 5828 C CA . PRO B 1 228 ? -82.447 -6.044 280.534 1.00 27.10 ? 228 PRO B CA 1 ATOM 5829 C C . PRO B 1 228 ? -81.380 -5.517 281.483 1.00 28.08 ? 228 PRO B C 1 ATOM 5830 O O . PRO B 1 228 ? -80.905 -6.230 282.369 1.00 37.31 ? 228 PRO B O 1 ATOM 5831 C CB . PRO B 1 228 ? -83.744 -6.391 281.276 1.00 31.67 ? 228 PRO B CB 1 ATOM 5832 C CG . PRO B 1 228 ? -84.234 -7.648 280.627 1.00 48.82 ? 228 PRO B CG 1 ATOM 5833 C CD . PRO B 1 228 ? -83.000 -8.402 280.244 1.00 30.72 ? 228 PRO B CD 1 ATOM 5834 N N . GLN B 1 229 ? -81.005 -4.255 281.291 1.00 28.87 ? 229 GLN B N 1 ATOM 5835 C CA . GLN B 1 229 ? -79.970 -3.615 282.089 1.00 26.62 ? 229 GLN B CA 1 ATOM 5836 C C . GLN B 1 229 ? -80.454 -2.243 282.547 1.00 27.50 ? 229 GLN B C 1 ATOM 5837 O O . GLN B 1 229 ? -81.572 -1.816 282.238 1.00 29.76 ? 229 GLN B O 1 ATOM 5838 C CB . GLN B 1 229 ? -78.657 -3.506 281.302 1.00 25.98 ? 229 GLN B CB 1 ATOM 5839 C CG . GLN B 1 229 ? -78.010 -4.845 280.963 1.00 28.21 ? 229 GLN B CG 1 ATOM 5840 C CD . GLN B 1 229 ? -77.412 -5.538 282.178 1.00 26.67 ? 229 GLN B CD 1 ATOM 5841 O OE1 . GLN B 1 229 ? -77.443 -5.011 283.290 1.00 24.75 ? 229 GLN B OE1 1 ATOM 5842 N NE2 . GLN B 1 229 ? -76.860 -6.727 281.966 1.00 38.15 ? 229 GLN B NE2 1 ATOM 5843 N N . LYS B 1 230 ? -79.596 -1.553 283.298 1.00 29.71 ? 230 LYS B N 1 ATOM 5844 C CA . LYS B 1 230 ? -79.930 -0.229 283.810 1.00 27.89 ? 230 LYS B CA 1 ATOM 5845 C C . LYS B 1 230 ? -80.143 0.752 282.661 1.00 24.68 ? 230 LYS B C 1 ATOM 5846 O O . LYS B 1 230 ? -79.430 0.713 281.655 1.00 24.91 ? 230 LYS B O 1 ATOM 5847 C CB . LYS B 1 230 ? -78.814 0.268 284.731 1.00 24.30 ? 230 LYS B CB 1 ATOM 5848 C CG . LYS B 1 230 ? -79.062 1.629 285.349 1.00 25.75 ? 230 LYS B CG 1 ATOM 5849 C CD . LYS B 1 230 ? -78.134 1.835 286.534 1.00 31.58 ? 230 LYS B CD 1 ATOM 5850 C CE . LYS B 1 230 ? -78.226 3.250 287.077 1.00 38.04 ? 230 LYS B CE 1 ATOM 5851 N NZ . LYS B 1 230 ? -77.543 4.244 286.209 1.00 26.72 ? 230 LYS B NZ 1 ATOM 5852 N N . SER B 1 231 ? -81.143 1.625 282.812 1.00 27.02 ? 231 SER B N 1 ATOM 5853 C CA . SER B 1 231 ? -81.585 2.622 281.838 1.00 29.33 ? 231 SER B CA 1 ATOM 5854 C C . SER B 1 231 ? -82.144 2.000 280.563 1.00 30.86 ? 231 SER B C 1 ATOM 5855 O O . SER B 1 231 ? -82.556 2.742 279.658 1.00 41.42 ? 231 SER B O 1 ATOM 5856 C CB . SER B 1 231 ? -80.476 3.611 281.451 1.00 29.63 ? 231 SER B CB 1 ATOM 5857 O OG . SER B 1 231 ? -79.531 3.005 280.589 1.00 36.92 ? 231 SER B OG 1 ATOM 5858 N N . VAL B 1 232 ? -82.150 0.675 280.443 1.00 33.41 ? 232 VAL B N 1 ATOM 5859 C CA . VAL B 1 232 ? -82.714 -0.018 279.289 1.00 33.55 ? 232 VAL B CA 1 ATOM 5860 C C . VAL B 1 232 ? -83.430 -1.268 279.778 1.00 38.08 ? 232 VAL B C 1 ATOM 5861 O O . VAL B 1 232 ? -83.268 -2.354 279.208 1.00 35.59 ? 232 VAL B O 1 ATOM 5862 C CB . VAL B 1 232 ? -81.639 -0.383 278.249 1.00 28.34 ? 232 VAL B CB 1 ATOM 5863 C CG1 . VAL B 1 232 ? -81.284 0.818 277.379 1.00 30.65 ? 232 VAL B CG1 1 ATOM 5864 C CG2 . VAL B 1 232 ? -80.398 -0.909 278.944 1.00 36.49 ? 232 VAL B CG2 1 ATOM 5865 N N . SER B 1 233 ? -84.242 -1.119 280.824 1.00 35.24 ? 233 SER B N 1 ATOM 5866 C CA . SER B 1 233 ? -84.900 -2.247 281.466 1.00 36.98 ? 233 SER B CA 1 ATOM 5867 C C . SER B 1 233 ? -86.374 -2.373 281.111 1.00 40.95 ? 233 SER B C 1 ATOM 5868 O O . SER B 1 233 ? -86.976 -3.407 281.415 1.00 44.07 ? 233 SER B O 1 ATOM 5869 C CB . SER B 1 233 ? -84.750 -2.151 282.988 1.00 41.70 ? 233 SER B CB 1 ATOM 5870 O OG . SER B 1 233 ? -85.275 -0.932 283.485 1.00 85.24 ? 233 SER B OG 1 ATOM 5871 N N . ALA B 1 234 ? -86.974 -1.353 280.499 1.00 43.54 ? 234 ALA B N 1 ATOM 5872 C CA . ALA B 1 234 ? -88.324 -1.501 279.976 1.00 49.54 ? 234 ALA B CA 1 ATOM 5873 C C . ALA B 1 234 ? -88.337 -2.571 278.892 1.00 52.13 ? 234 ALA B C 1 ATOM 5874 O O . ALA B 1 234 ? -87.333 -2.812 278.218 1.00 58.61 ? 234 ALA B O 1 ATOM 5875 C CB . ALA B 1 234 ? -88.834 -0.171 279.422 1.00 71.83 ? 234 ALA B CB 1 ATOM 5876 N N . TRP B 1 235 ? -89.480 -3.235 278.729 1.00 52.23 ? 235 TRP B N 1 ATOM 5877 C CA . TRP B 1 235 ? -89.508 -4.365 277.811 1.00 57.93 ? 235 TRP B CA 1 ATOM 5878 C C . TRP B 1 235 ? -89.861 -3.975 276.384 1.00 58.17 ? 235 TRP B C 1 ATOM 5879 O O . TRP B 1 235 ? -89.628 -4.772 275.469 1.00 78.06 ? 235 TRP B O 1 ATOM 5880 C CB . TRP B 1 235 ? -90.479 -5.446 278.291 1.00 70.96 ? 235 TRP B CB 1 ATOM 5881 C CG . TRP B 1 235 ? -90.018 -6.806 277.864 1.00 105.19 ? 235 TRP B CG 1 ATOM 5882 C CD1 . TRP B 1 235 ? -88.891 -7.449 278.283 1.00 92.25 ? 235 TRP B CD1 1 ATOM 5883 C CD2 . TRP B 1 235 ? -90.635 -7.668 276.900 1.00 105.53 ? 235 TRP B CD2 1 ATOM 5884 N NE1 . TRP B 1 235 ? -88.779 -8.665 277.659 1.00 87.48 ? 235 TRP B NE1 1 ATOM 5885 C CE2 . TRP B 1 235 ? -89.836 -8.825 276.805 1.00 80.65 ? 235 TRP B CE2 1 ATOM 5886 C CE3 . TRP B 1 235 ? -91.790 -7.580 276.118 1.00 101.56 ? 235 TRP B CE3 1 ATOM 5887 C CZ2 . TRP B 1 235 ? -90.154 -9.885 275.961 1.00 74.26 ? 235 TRP B CZ2 1 ATOM 5888 C CZ3 . TRP B 1 235 ? -92.104 -8.636 275.279 1.00 98.52 ? 235 TRP B CZ3 1 ATOM 5889 C CH2 . TRP B 1 235 ? -91.289 -9.772 275.208 1.00 80.44 ? 235 TRP B CH2 1 ATOM 5890 N N . ASN B 1 236 ? -90.416 -2.784 276.164 1.00 55.90 ? 236 ASN B N 1 ATOM 5891 C CA . ASN B 1 236 ? -90.526 -2.241 274.818 1.00 66.54 ? 236 ASN B CA 1 ATOM 5892 C C . ASN B 1 236 ? -89.265 -1.493 274.401 1.00 47.17 ? 236 ASN B C 1 ATOM 5893 O O . ASN B 1 236 ? -89.295 -0.728 273.429 1.00 38.79 ? 236 ASN B O 1 ATOM 5894 C CB . ASN B 1 236 ? -91.762 -1.340 274.696 1.00 60.43 ? 236 ASN B CB 1 ATOM 5895 C CG . ASN B 1 236 ? -91.718 -0.135 275.620 1.00 53.76 ? 236 ASN B CG 1 ATOM 5896 O OD1 . ASN B 1 236 ? -90.706 0.146 276.261 1.00 54.39 ? 236 ASN B OD1 1 ATOM 5897 N ND2 . ASN B 1 236 ? -92.827 0.592 275.681 1.00 65.05 ? 236 ASN B ND2 1 ATOM 5898 N N . GLU B 1 237 ? -88.168 -1.697 275.119 1.00 44.93 ? 237 GLU B N 1 ATOM 5899 C CA . GLU B 1 237 ? -86.904 -1.054 274.794 1.00 40.77 ? 237 GLU B CA 1 ATOM 5900 C C . GLU B 1 237 ? -86.352 -1.640 273.503 1.00 38.90 ? 237 GLU B C 1 ATOM 5901 O O . GLU B 1 237 ? -86.196 -2.865 273.407 1.00 52.36 ? 237 GLU B O 1 ATOM 5902 C CB . GLU B 1 237 ? -85.905 -1.244 275.931 1.00 41.83 ? 237 GLU B CB 1 ATOM 5903 C CG . GLU B 1 237 ? -84.751 -0.259 275.927 1.00 57.90 ? 237 GLU B CG 1 ATOM 5904 C CD . GLU B 1 237 ? -85.217 1.179 276.043 1.00 55.08 ? 237 GLU B CD 1 ATOM 5905 O OE1 . GLU B 1 237 ? -85.918 1.499 277.025 1.00 48.11 ? 237 GLU B OE1 1 ATOM 5906 O OE2 . GLU B 1 237 ? -84.883 1.988 275.152 1.00 40.73 ? 237 GLU B OE2 1 ATOM 5907 N N . PRO B 1 238 ? -86.049 -0.822 272.495 1.00 34.84 ? 238 PRO B N 1 ATOM 5908 C CA . PRO B 1 238 ? -85.537 -1.381 271.235 1.00 30.45 ? 238 PRO B CA 1 ATOM 5909 C C . PRO B 1 238 ? -84.153 -1.991 271.365 1.00 34.39 ? 238 PRO B C 1 ATOM 5910 O O . PRO B 1 238 ? -83.827 -2.916 270.611 1.00 30.87 ? 238 PRO B O 1 ATOM 5911 C CB . PRO B 1 238 ? -85.534 -0.170 270.294 1.00 26.39 ? 238 PRO B CB 1 ATOM 5912 C CG . PRO B 1 238 ? -85.437 1.007 271.209 1.00 28.58 ? 238 PRO B CG 1 ATOM 5913 C CD . PRO B 1 238 ? -86.198 0.641 272.440 1.00 32.80 ? 238 PRO B CD 1 ATOM 5914 N N . TYR B 1 239 ? -83.331 -1.511 272.298 1.00 55.89 ? 239 TYR B N 1 ATOM 5915 C CA . TYR B 1 239 ? -81.970 -2.009 272.467 1.00 32.79 ? 239 TYR B CA 1 ATOM 5916 C C . TYR B 1 239 ? -81.673 -2.145 273.951 1.00 30.25 ? 239 TYR B C 1 ATOM 5917 O O . TYR B 1 239 ? -81.770 -1.166 274.697 1.00 39.25 ? 239 TYR B O 1 ATOM 5918 C CB . TYR B 1 239 ? -80.953 -1.074 271.804 1.00 24.67 ? 239 TYR B CB 1 ATOM 5919 C CG . TYR B 1 239 ? -81.224 -0.811 270.342 1.00 21.78 ? 239 TYR B CG 1 ATOM 5920 C CD1 . TYR B 1 239 ? -81.078 -1.816 269.397 1.00 20.24 ? 239 TYR B CD1 1 ATOM 5921 C CD2 . TYR B 1 239 ? -81.628 0.443 269.907 1.00 21.17 ? 239 TYR B CD2 1 ATOM 5922 C CE1 . TYR B 1 239 ? -81.327 -1.580 268.059 1.00 20.45 ? 239 TYR B CE1 1 ATOM 5923 C CE2 . TYR B 1 239 ? -81.879 0.690 268.571 1.00 29.22 ? 239 TYR B CE2 1 ATOM 5924 C CZ . TYR B 1 239 ? -81.727 -0.326 267.652 1.00 23.22 ? 239 TYR B CZ 1 ATOM 5925 O OH . TYR B 1 239 ? -81.975 -0.087 266.320 1.00 19.57 ? 239 TYR B OH 1 ATOM 5926 N N . LYS B 1 240 ? -81.312 -3.356 274.377 1.00 26.73 ? 240 LYS B N 1 ATOM 5927 C CA . LYS B 1 240 ? -80.879 -3.585 275.750 1.00 24.01 ? 240 LYS B CA 1 ATOM 5928 C C . LYS B 1 240 ? -79.455 -4.123 275.777 1.00 23.78 ? 240 LYS B C 1 ATOM 5929 O O . LYS B 1 240 ? -78.642 -3.792 274.908 1.00 23.50 ? 240 LYS B O 1 ATOM 5930 C CB . LYS B 1 240 ? -81.808 -4.564 276.469 1.00 27.24 ? 240 LYS B CB 1 ATOM 5931 C CG . LYS B 1 240 ? -83.290 -4.310 276.288 1.00 33.85 ? 240 LYS B CG 1 ATOM 5932 C CD . LYS B 1 240 ? -84.083 -5.383 277.013 1.00 33.35 ? 240 LYS B CD 1 ATOM 5933 C CE . LYS B 1 240 ? -85.556 -5.332 276.667 1.00 42.99 ? 240 LYS B CE 1 ATOM 5934 N NZ . LYS B 1 240 ? -86.232 -6.592 277.074 1.00 45.63 ? 240 LYS B NZ 1 ATOM 5935 N N . GLY B 1 241 ? -79.153 -4.958 276.768 1.00 28.38 ? 241 GLY B N 1 ATOM 5936 C CA . GLY B 1 241 ? -77.863 -5.600 276.888 1.00 37.37 ? 241 GLY B CA 1 ATOM 5937 C C . GLY B 1 241 ? -76.723 -4.603 277.036 1.00 20.39 ? 241 GLY B C 1 ATOM 5938 O O . GLY B 1 241 ? -76.908 -3.433 277.382 1.00 21.26 ? 241 GLY B O 1 ATOM 5939 N N . ASN B 1 242 ? -75.516 -5.098 276.760 1.00 19.15 ? 242 ASN B N 1 ATOM 5940 C CA . ASN B 1 242 ? -74.340 -4.238 276.819 1.00 20.17 ? 242 ASN B CA 1 ATOM 5941 C C . ASN B 1 242 ? -74.373 -3.186 275.719 1.00 22.28 ? 242 ASN B C 1 ATOM 5942 O O . ASN B 1 242 ? -73.958 -2.042 275.936 1.00 23.25 ? 242 ASN B O 1 ATOM 5943 C CB . ASN B 1 242 ? -73.069 -5.079 276.721 1.00 20.96 ? 242 ASN B CB 1 ATOM 5944 C CG . ASN B 1 242 ? -72.987 -6.127 277.806 1.00 22.00 ? 242 ASN B CG 1 ATOM 5945 O OD1 . ASN B 1 242 ? -73.589 -5.979 278.868 1.00 20.72 ? 242 ASN B OD1 1 ATOM 5946 N ND2 . ASN B 1 242 ? -72.245 -7.196 277.545 1.00 25.14 ? 242 ASN B ND2 1 ATOM 5947 N N . PHE B 1 243 ? -74.867 -3.552 274.534 1.00 20.31 ? 243 PHE B N 1 ATOM 5948 C CA . PHE B 1 243 ? -74.937 -2.591 273.438 1.00 19.35 ? 243 PHE B CA 1 ATOM 5949 C C . PHE B 1 243 ? -75.863 -1.432 273.779 1.00 19.89 ? 243 PHE B C 1 ATOM 5950 O O . PHE B 1 243 ? -75.538 -0.270 273.511 1.00 21.83 ? 243 PHE B O 1 ATOM 5951 C CB . PHE B 1 243 ? -75.397 -3.283 272.155 1.00 17.75 ? 243 PHE B CB 1 ATOM 5952 C CG . PHE B 1 243 ? -74.339 -4.129 271.504 1.00 19.70 ? 243 PHE B CG 1 ATOM 5953 C CD1 . PHE B 1 243 ? -73.098 -4.298 272.096 1.00 19.70 ? 243 PHE B CD1 1 ATOM 5954 C CD2 . PHE B 1 243 ? -74.586 -4.750 270.292 1.00 22.89 ? 243 PHE B CD2 1 ATOM 5955 C CE1 . PHE B 1 243 ? -72.127 -5.074 271.494 1.00 23.87 ? 243 PHE B CE1 1 ATOM 5956 C CE2 . PHE B 1 243 ? -73.619 -5.526 269.685 1.00 24.37 ? 243 PHE B CE2 1 ATOM 5957 C CZ . PHE B 1 243 ? -72.388 -5.689 270.287 1.00 24.97 ? 243 PHE B CZ 1 ATOM 5958 N N . GLY B 1 244 ? -77.018 -1.727 274.378 1.00 21.44 ? 244 GLY B N 1 ATOM 5959 C CA . GLY B 1 244 ? -77.951 -0.667 274.723 1.00 23.72 ? 244 GLY B CA 1 ATOM 5960 C C . GLY B 1 244 ? -77.374 0.323 275.715 1.00 21.00 ? 244 GLY B C 1 ATOM 5961 O O . GLY B 1 244 ? -77.587 1.532 275.596 1.00 23.33 ? 244 GLY B O 1 ATOM 5962 N N . GLN B 1 245 ? -76.633 -0.174 276.707 1.00 19.46 ? 245 GLN B N 1 ATOM 5963 C CA . GLN B 1 245 ? -76.005 0.725 277.669 1.00 21.70 ? 245 GLN B CA 1 ATOM 5964 C C . GLN B 1 245 ? -74.846 1.487 277.037 1.00 21.66 ? 245 GLN B C 1 ATOM 5965 O O . GLN B 1 245 ? -74.628 2.663 277.350 1.00 20.22 ? 245 GLN B O 1 ATOM 5966 C CB . GLN B 1 245 ? -75.532 -0.058 278.893 1.00 21.03 ? 245 GLN B CB 1 ATOM 5967 C CG . GLN B 1 245 ? -76.654 -0.499 279.818 1.00 19.76 ? 245 GLN B CG 1 ATOM 5968 C CD . GLN B 1 245 ? -76.138 -1.150 281.086 1.00 25.72 ? 245 GLN B CD 1 ATOM 5969 O OE1 . GLN B 1 245 ? -75.214 -1.962 281.050 1.00 39.11 ? 245 GLN B OE1 1 ATOM 5970 N NE2 . GLN B 1 245 ? -76.734 -0.793 282.218 1.00 22.98 ? 245 GLN B NE2 1 ATOM 5971 N N . LEU B 1 246 ? -74.095 0.836 276.144 1.00 34.13 ? 246 LEU B N 1 ATOM 5972 C CA . LEU B 1 246 ? -72.995 1.518 275.467 1.00 20.79 ? 246 LEU B CA 1 ATOM 5973 C C . LEU B 1 246 ? -73.499 2.688 274.632 1.00 21.99 ? 246 LEU B C 1 ATOM 5974 O O . LEU B 1 246 ? -72.829 3.722 274.533 1.00 22.28 ? 246 LEU B O 1 ATOM 5975 C CB . LEU B 1 246 ? -72.217 0.531 274.597 1.00 20.71 ? 246 LEU B CB 1 ATOM 5976 C CG . LEU B 1 246 ? -71.290 -0.445 275.324 1.00 20.89 ? 246 LEU B CG 1 ATOM 5977 C CD1 . LEU B 1 246 ? -70.743 -1.481 274.358 1.00 32.41 ? 246 LEU B CD1 1 ATOM 5978 C CD2 . LEU B 1 246 ? -70.154 0.307 275.995 1.00 21.17 ? 246 LEU B CD2 1 ATOM 5979 N N . MET B 1 247 ? -74.677 2.545 274.021 1.00 23.12 ? 247 MET B N 1 ATOM 5980 C CA . MET B 1 247 ? -75.272 3.663 273.297 1.00 22.71 ? 247 MET B CA 1 ATOM 5981 C C . MET B 1 247 ? -75.589 4.812 274.245 1.00 22.09 ? 247 MET B C 1 ATOM 5982 O O . MET B 1 247 ? -75.284 5.975 273.957 1.00 20.53 ? 247 MET B O 1 ATOM 5983 C CB . MET B 1 247 ? -76.537 3.208 272.570 1.00 19.69 ? 247 MET B CB 1 ATOM 5984 C CG . MET B 1 247 ? -76.332 2.059 271.602 1.00 16.54 ? 247 MET B CG 1 ATOM 5985 S SD . MET B 1 247 ? -77.896 1.451 270.946 1.00 18.11 ? 247 MET B SD 1 ATOM 5986 C CE . MET B 1 247 ? -77.354 -0.023 270.088 1.00 21.58 ? 247 MET B CE 1 ATOM 5987 N N . ALA B 1 248 ? -76.200 4.500 275.390 1.00 23.11 ? 248 ALA B N 1 ATOM 5988 C CA . ALA B 1 248 ? -76.561 5.539 276.346 1.00 27.31 ? 248 ALA B CA 1 ATOM 5989 C C . ALA B 1 248 ? -75.343 6.074 277.086 1.00 27.92 ? 248 ALA B C 1 ATOM 5990 O O . ALA B 1 248 ? -75.293 7.266 277.409 1.00 30.89 ? 248 ALA B O 1 ATOM 5991 C CB . ALA B 1 248 ? -77.591 5.001 277.339 1.00 32.03 ? 248 ALA B CB 1 ATOM 5992 N N . ALA B 1 249 ? -74.358 5.217 277.365 1.00 26.36 ? 249 ALA B N 1 ATOM 5993 C CA . ALA B 1 249 ? -73.154 5.681 278.044 1.00 25.89 ? 249 ALA B CA 1 ATOM 5994 C C . ALA B 1 249 ? -72.303 6.561 277.139 1.00 20.33 ? 249 ALA B C 1 ATOM 5995 O O . ALA B 1 249 ? -71.621 7.470 277.626 1.00 21.50 ? 249 ALA B O 1 ATOM 5996 C CB . ALA B 1 249 ? -72.339 4.491 278.546 1.00 35.49 ? 249 ALA B CB 1 ATOM 5997 N N . LYS B 1 250 ? -72.329 6.309 275.828 1.00 21.00 ? 250 LYS B N 1 ATOM 5998 C CA . LYS B 1 250 ? -71.575 7.145 274.901 1.00 19.33 ? 250 LYS B CA 1 ATOM 5999 C C . LYS B 1 250 ? -72.121 8.565 274.857 1.00 19.39 ? 250 LYS B C 1 ATOM 6000 O O . LYS B 1 250 ? -71.373 9.507 274.575 1.00 18.44 ? 250 LYS B O 1 ATOM 6001 C CB . LYS B 1 250 ? -71.593 6.527 273.504 1.00 24.27 ? 250 LYS B CB 1 ATOM 6002 C CG . LYS B 1 250 ? -70.562 7.106 272.552 1.00 19.29 ? 250 LYS B CG 1 ATOM 6003 C CD . LYS B 1 250 ? -70.465 6.274 271.287 1.00 17.30 ? 250 LYS B CD 1 ATOM 6004 C CE . LYS B 1 250 ? -69.388 6.803 270.360 1.00 16.27 ? 250 LYS B CE 1 ATOM 6005 N NZ . LYS B 1 250 ? -69.288 5.979 269.127 1.00 18.71 ? 250 LYS B NZ 1 ATOM 6006 N N . LEU B 1 251 ? -73.416 8.739 275.125 1.00 17.79 ? 251 LEU B N 1 ATOM 6007 C CA . LEU B 1 251 ? -73.980 10.082 275.194 1.00 17.32 ? 251 LEU B CA 1 ATOM 6008 C C . LEU B 1 251 ? -73.470 10.821 276.424 1.00 19.90 ? 251 LEU B C 1 ATOM 6009 O O . LEU B 1 251 ? -73.039 11.976 276.333 1.00 34.74 ? 251 LEU B O 1 ATOM 6010 C CB . LEU B 1 251 ? -75.507 10.011 275.196 1.00 17.96 ? 251 LEU B CB 1 ATOM 6011 C CG . LEU B 1 251 ? -76.140 9.288 274.005 1.00 21.13 ? 251 LEU B CG 1 ATOM 6012 C CD1 . LEU B 1 251 ? -77.655 9.268 274.128 1.00 21.00 ? 251 LEU B CD1 1 ATOM 6013 C CD2 . LEU B 1 251 ? -75.713 9.936 272.696 1.00 16.62 ? 251 LEU B CD2 1 ATOM 6014 N N . ALA B 1 252 ? -73.501 10.164 277.586 1.00 18.42 ? 252 ALA B N 1 ATOM 6015 C CA . ALA B 1 252 ? -72.986 10.777 278.804 1.00 17.95 ? 252 ALA B CA 1 ATOM 6016 C C . ALA B 1 252 ? -71.476 10.969 278.761 1.00 18.56 ? 252 ALA B C 1 ATOM 6017 O O . ALA B 1 252 ? -70.956 11.843 279.461 1.00 19.04 ? 252 ALA B O 1 ATOM 6018 C CB . ALA B 1 252 ? -73.368 9.935 280.021 1.00 30.28 ? 252 ALA B CB 1 ATOM 6019 N N . ASN B 1 253 ? -70.764 10.176 277.963 1.00 18.22 ? 253 ASN B N 1 ATOM 6020 C CA . ASN B 1 253 ? -69.317 10.299 277.795 1.00 17.62 ? 253 ASN B CA 1 ATOM 6021 C C . ASN B 1 253 ? -69.022 10.450 276.309 1.00 19.18 ? 253 ASN B C 1 ATOM 6022 O O . ASN B 1 253 ? -68.637 9.483 275.638 1.00 32.51 ? 253 ASN B O 1 ATOM 6023 C CB . ASN B 1 253 ? -68.585 9.095 278.388 1.00 20.45 ? 253 ASN B CB 1 ATOM 6024 C CG . ASN B 1 253 ? -68.927 8.867 279.845 1.00 24.63 ? 253 ASN B CG 1 ATOM 6025 O OD1 . ASN B 1 253 ? -68.260 9.385 280.740 1.00 25.93 ? 253 ASN B OD1 1 ATOM 6026 N ND2 . ASN B 1 253 ? -69.971 8.086 280.092 1.00 25.30 ? 253 ASN B ND2 1 ATOM 6027 N N . PRO B 1 254 ? -69.200 11.654 275.758 1.00 20.12 ? 254 PRO B N 1 ATOM 6028 C CA . PRO B 1 254 ? -68.934 11.845 274.323 1.00 21.05 ? 254 PRO B CA 1 ATOM 6029 C C . PRO B 1 254 ? -67.460 11.793 273.967 1.00 22.48 ? 254 PRO B C 1 ATOM 6030 O O . PRO B 1 254 ? -67.133 11.572 272.794 1.00 22.18 ? 254 PRO B O 1 ATOM 6031 C CB . PRO B 1 254 ? -69.532 13.228 274.039 1.00 22.67 ? 254 PRO B CB 1 ATOM 6032 C CG . PRO B 1 254 ? -69.436 13.941 275.344 1.00 18.73 ? 254 PRO B CG 1 ATOM 6033 C CD . PRO B 1 254 ? -69.652 12.896 276.408 1.00 19.19 ? 254 PRO B CD 1 ATOM 6034 N N . HIS B 1 255 ? -66.562 11.989 274.934 1.00 21.92 ? 255 HIS B N 1 ATOM 6035 C CA . HIS B 1 255 ? -65.136 11.846 274.663 1.00 21.63 ? 255 HIS B CA 1 ATOM 6036 C C . HIS B 1 255 ? -64.761 10.396 274.393 1.00 19.94 ? 255 HIS B C 1 ATOM 6037 O O . HIS B 1 255 ? -63.758 10.129 273.722 1.00 20.98 ? 255 HIS B O 1 ATOM 6038 C CB . HIS B 1 255 ? -64.324 12.373 275.844 1.00 28.87 ? 255 HIS B CB 1 ATOM 6039 C CG . HIS B 1 255 ? -64.416 11.511 277.063 1.00 25.20 ? 255 HIS B CG 1 ATOM 6040 N ND1 . HIS B 1 255 ? -65.430 11.634 277.988 1.00 30.95 ? 255 HIS B ND1 1 ATOM 6041 C CD2 . HIS B 1 255 ? -63.628 10.501 277.503 1.00 24.63 ? 255 HIS B CD2 1 ATOM 6042 C CE1 . HIS B 1 255 ? -65.259 10.743 278.948 1.00 40.90 ? 255 HIS B CE1 1 ATOM 6043 N NE2 . HIS B 1 255 ? -64.173 10.042 278.677 1.00 38.45 ? 255 HIS B NE2 1 ATOM 6044 N N . LEU B 1 256 ? -65.550 9.457 274.906 1.00 21.81 ? 256 LEU B N 1 ATOM 6045 C CA . LEU B 1 256 ? -65.202 8.046 274.840 1.00 21.39 ? 256 LEU B CA 1 ATOM 6046 C C . LEU B 1 256 ? -65.232 7.535 273.405 1.00 20.21 ? 256 LEU B C 1 ATOM 6047 O O . LEU B 1 256 ? -66.107 7.896 272.614 1.00 20.29 ? 256 LEU B O 1 ATOM 6048 C CB . LEU B 1 256 ? -66.165 7.230 275.702 1.00 19.56 ? 256 LEU B CB 1 ATOM 6049 C CG . LEU B 1 256 ? -65.994 5.712 275.693 1.00 21.08 ? 256 LEU B CG 1 ATOM 6050 C CD1 . LEU B 1 256 ? -64.735 5.306 276.444 1.00 35.82 ? 256 LEU B CD1 1 ATOM 6051 C CD2 . LEU B 1 256 ? -67.221 5.033 276.278 1.00 20.53 ? 256 LEU B CD2 1 ATOM 6052 N N . LYS B 1 257 ? -64.260 6.690 273.075 1.00 20.17 ? 257 LYS B N 1 ATOM 6053 C CA . LYS B 1 257 ? -64.210 5.988 271.800 1.00 21.98 ? 257 LYS B CA 1 ATOM 6054 C C . LYS B 1 257 ? -64.395 4.501 272.062 1.00 23.24 ? 257 LYS B C 1 ATOM 6055 O O . LYS B 1 257 ? -63.653 3.910 272.853 1.00 52.65 ? 257 LYS B O 1 ATOM 6056 C CB . LYS B 1 257 ? -62.882 6.243 271.083 1.00 36.48 ? 257 LYS B CB 1 ATOM 6057 C CG . LYS B 1 257 ? -62.367 7.671 271.202 1.00 28.10 ? 257 LYS B CG 1 ATOM 6058 C CD . LYS B 1 257 ? -63.296 8.665 270.525 1.00 32.39 ? 257 LYS B CD 1 ATOM 6059 C CE . LYS B 1 257 ? -62.732 10.076 270.590 1.00 31.66 ? 257 LYS B CE 1 ATOM 6060 N NZ . LYS B 1 257 ? -63.662 11.081 270.005 1.00 29.38 ? 257 LYS B NZ 1 ATOM 6061 N N . ILE B 1 258 ? -65.384 3.900 271.408 1.00 20.50 ? 258 ILE B N 1 ATOM 6062 C CA . ILE B 1 258 ? -65.745 2.504 271.628 1.00 21.28 ? 258 ILE B CA 1 ATOM 6063 C C . ILE B 1 258 ? -65.297 1.693 270.422 1.00 20.71 ? 258 ILE B C 1 ATOM 6064 O O . ILE B 1 258 ? -65.654 2.013 269.282 1.00 21.22 ? 258 ILE B O 1 ATOM 6065 C CB . ILE B 1 258 ? -67.255 2.347 271.872 1.00 22.74 ? 258 ILE B CB 1 ATOM 6066 C CG1 . ILE B 1 258 ? -67.679 3.165 273.091 1.00 20.75 ? 258 ILE B CG1 1 ATOM 6067 C CG2 . ILE B 1 258 ? -67.608 0.886 272.077 1.00 21.78 ? 258 ILE B CG2 1 ATOM 6068 C CD1 . ILE B 1 258 ? -69.144 3.039 273.432 1.00 19.26 ? 258 ILE B CD1 1 ATOM 6069 N N . LEU B 1 259 ? -64.514 0.643 270.673 1.00 18.91 ? 259 LEU B N 1 ATOM 6070 C CA . LEU B 1 259 ? -63.980 -0.187 269.610 1.00 20.97 ? 259 LEU B CA 1 ATOM 6071 C C . LEU B 1 259 ? -64.354 -1.648 269.826 1.00 22.82 ? 259 LEU B C 1 ATOM 6072 O O . LEU B 1 259 ? -64.299 -2.144 270.957 1.00 22.83 ? 259 LEU B O 1 ATOM 6073 C CB . LEU B 1 259 ? -62.449 -0.069 269.521 1.00 22.12 ? 259 LEU B CB 1 ATOM 6074 C CG . LEU B 1 259 ? -61.844 1.218 268.954 1.00 23.01 ? 259 LEU B CG 1 ATOM 6075 C CD1 . LEU B 1 259 ? -61.849 2.340 269.984 1.00 30.52 ? 259 LEU B CD1 1 ATOM 6076 C CD2 . LEU B 1 259 ? -60.435 0.958 268.444 1.00 23.90 ? 259 LEU B CD2 1 ATOM 6077 N N . PRO B 1 260 ? -64.742 -2.360 268.767 1.00 19.92 ? 260 PRO B N 1 ATOM 6078 C CA . PRO B 1 260 ? -65.042 -3.791 268.900 1.00 20.43 ? 260 PRO B CA 1 ATOM 6079 C C . PRO B 1 260 ? -63.772 -4.626 268.807 1.00 23.44 ? 260 PRO B C 1 ATOM 6080 O O . PRO B 1 260 ? -62.987 -4.485 267.866 1.00 24.44 ? 260 PRO B O 1 ATOM 6081 C CB . PRO B 1 260 ? -65.979 -4.062 267.719 1.00 22.79 ? 260 PRO B CB 1 ATOM 6082 C CG . PRO B 1 260 ? -65.529 -3.083 266.682 1.00 22.19 ? 260 PRO B CG 1 ATOM 6083 C CD . PRO B 1 260 ? -65.081 -1.847 267.429 1.00 19.23 ? 260 PRO B CD 1 ATOM 6084 N N . SER B 1 261 ? -63.574 -5.498 269.791 1.00 29.95 ? 261 SER B N 1 ATOM 6085 C CA . SER B 1 261 ? -62.420 -6.391 269.820 1.00 24.50 ? 261 SER B CA 1 ATOM 6086 C C . SER B 1 261 ? -62.800 -7.693 269.127 1.00 20.37 ? 261 SER B C 1 ATOM 6087 O O . SER B 1 261 ? -63.592 -8.480 269.657 1.00 19.41 ? 261 SER B O 1 ATOM 6088 C CB . SER B 1 261 ? -61.963 -6.637 271.255 1.00 22.93 ? 261 SER B CB 1 ATOM 6089 O OG . SER B 1 261 ? -61.440 -5.453 271.829 1.00 40.39 ? 261 SER B OG 1 ATOM 6090 N N . ILE B 1 262 ? -62.240 -7.919 267.944 1.00 19.25 ? 262 ILE B N 1 ATOM 6091 C CA . ILE B 1 262 ? -62.549 -9.087 267.130 1.00 19.44 ? 262 ILE B CA 1 ATOM 6092 C C . ILE B 1 262 ? -61.467 -10.129 267.374 1.00 20.92 ? 262 ILE B C 1 ATOM 6093 O O . ILE B 1 262 ? -60.323 -9.965 266.938 1.00 33.70 ? 262 ILE B O 1 ATOM 6094 C CB . ILE B 1 262 ? -62.646 -8.727 265.642 1.00 20.12 ? 262 ILE B CB 1 ATOM 6095 C CG1 . ILE B 1 262 ? -63.685 -7.626 265.427 1.00 18.88 ? 262 ILE B CG1 1 ATOM 6096 C CG2 . ILE B 1 262 ? -62.990 -9.958 264.818 1.00 21.79 ? 262 ILE B CG2 1 ATOM 6097 C CD1 . ILE B 1 262 ? -63.824 -7.195 263.985 1.00 24.55 ? 262 ILE B CD1 1 ATOM 6098 N N . GLY B 1 263 ? -61.824 -11.205 268.070 1.00 19.66 ? 263 GLY B N 1 ATOM 6099 C CA . GLY B 1 263 ? -60.891 -12.291 268.294 1.00 23.59 ? 263 GLY B CA 1 ATOM 6100 C C . GLY B 1 263 ? -60.668 -12.627 269.753 1.00 27.45 ? 263 GLY B C 1 ATOM 6101 O O . GLY B 1 263 ? -61.623 -12.858 270.500 1.00 31.90 ? 263 GLY B O 1 ATOM 6102 N N . GLY B 1 264 ? -59.411 -12.658 270.168 1.00 26.56 ? 264 GLY B N 1 ATOM 6103 C CA . GLY B 1 264 ? -59.043 -13.022 271.517 1.00 27.03 ? 264 GLY B CA 1 ATOM 6104 C C . GLY B 1 264 ? -58.268 -14.323 271.568 1.00 30.23 ? 264 GLY B C 1 ATOM 6105 O O . GLY B 1 264 ? -57.708 -14.796 270.575 1.00 41.13 ? 264 GLY B O 1 ATOM 6106 N N . TRP B 1 265 ? -58.242 -14.915 272.763 1.00 29.79 ? 265 TRP B N 1 ATOM 6107 C CA . TRP B 1 265 ? -57.525 -16.173 272.946 1.00 31.05 ? 265 TRP B CA 1 ATOM 6108 C C . TRP B 1 265 ? -58.244 -17.327 272.258 1.00 26.70 ? 265 TRP B C 1 ATOM 6109 O O . TRP B 1 265 ? -57.608 -18.153 271.592 1.00 27.50 ? 265 TRP B O 1 ATOM 6110 C CB . TRP B 1 265 ? -57.350 -16.463 274.437 1.00 41.70 ? 265 TRP B CB 1 ATOM 6111 C CG . TRP B 1 265 ? -56.612 -17.736 274.731 1.00 33.00 ? 265 TRP B CG 1 ATOM 6112 C CD1 . TRP B 1 265 ? -57.135 -18.886 275.249 1.00 29.28 ? 265 TRP B CD1 1 ATOM 6113 C CD2 . TRP B 1 265 ? -55.215 -17.986 274.532 1.00 32.80 ? 265 TRP B CD2 1 ATOM 6114 N NE1 . TRP B 1 265 ? -56.152 -19.836 275.382 1.00 28.45 ? 265 TRP B NE1 1 ATOM 6115 C CE2 . TRP B 1 265 ? -54.964 -19.309 274.948 1.00 33.19 ? 265 TRP B CE2 1 ATOM 6116 C CE3 . TRP B 1 265 ? -54.152 -17.221 274.040 1.00 32.88 ? 265 TRP B CE3 1 ATOM 6117 C CZ2 . TRP B 1 265 ? -53.696 -19.883 274.888 1.00 37.52 ? 265 TRP B CZ2 1 ATOM 6118 C CZ3 . TRP B 1 265 ? -52.894 -17.793 273.981 1.00 32.42 ? 265 TRP B CZ3 1 ATOM 6119 C CH2 . TRP B 1 265 ? -52.677 -19.111 274.403 1.00 35.53 ? 265 TRP B CH2 1 ATOM 6120 N N . THR B 1 266 ? -59.567 -17.398 272.399 1.00 25.69 ? 266 THR B N 1 ATOM 6121 C CA . THR B 1 266 ? -60.341 -18.525 271.899 1.00 24.50 ? 266 THR B CA 1 ATOM 6122 C C . THR B 1 266 ? -60.976 -18.275 270.537 1.00 25.50 ? 266 THR B C 1 ATOM 6123 O O . THR B 1 266 ? -61.433 -19.231 269.903 1.00 25.94 ? 266 THR B O 1 ATOM 6124 C CB . THR B 1 266 ? -61.443 -18.894 272.900 1.00 22.42 ? 266 THR B CB 1 ATOM 6125 O OG1 . THR B 1 266 ? -62.319 -17.775 273.082 1.00 20.38 ? 266 THR B OG1 1 ATOM 6126 C CG2 . THR B 1 266 ? -60.837 -19.276 274.240 1.00 23.52 ? 266 THR B CG2 1 ATOM 6127 N N . LEU B 1 267 ? -61.015 -17.028 270.071 1.00 27.46 ? 267 LEU B N 1 ATOM 6128 C CA . LEU B 1 267 ? -61.701 -16.686 268.832 1.00 25.21 ? 267 LEU B CA 1 ATOM 6129 C C . LEU B 1 267 ? -60.744 -16.306 267.709 1.00 37.59 ? 267 LEU B C 1 ATOM 6130 O O . LEU B 1 267 ? -61.183 -15.746 266.699 1.00 56.84 ? 267 LEU B O 1 ATOM 6131 C CB . LEU B 1 267 ? -62.693 -15.547 269.081 1.00 23.64 ? 267 LEU B CB 1 ATOM 6132 C CG . LEU B 1 267 ? -63.877 -15.886 269.986 1.00 26.04 ? 267 LEU B CG 1 ATOM 6133 C CD1 . LEU B 1 267 ? -64.608 -14.625 270.417 1.00 23.35 ? 267 LEU B CD1 1 ATOM 6134 C CD2 . LEU B 1 267 ? -64.823 -16.843 269.284 1.00 36.17 ? 267 LEU B CD2 1 ATOM 6135 N N . SER B 1 268 ? -59.453 -16.599 267.853 1.00 30.16 ? 268 SER B N 1 ATOM 6136 C CA . SER B 1 268 ? -58.465 -16.231 266.849 1.00 28.32 ? 268 SER B CA 1 ATOM 6137 C C . SER B 1 268 ? -58.281 -17.287 265.768 1.00 27.76 ? 268 SER B C 1 ATOM 6138 O O . SER B 1 268 ? -57.535 -17.044 264.813 1.00 26.33 ? 268 SER B O 1 ATOM 6139 C CB . SER B 1 268 ? -57.114 -15.953 267.516 1.00 35.28 ? 268 SER B CB 1 ATOM 6140 O OG . SER B 1 268 ? -57.185 -14.818 268.360 1.00 38.57 ? 268 SER B OG 1 ATOM 6141 N N . ASP B 1 269 ? -58.941 -18.437 265.888 1.00 31.00 ? 269 ASP B N 1 ATOM 6142 C CA . ASP B 1 269 ? -58.724 -19.521 264.933 1.00 32.43 ? 269 ASP B CA 1 ATOM 6143 C C . ASP B 1 269 ? -59.084 -19.171 263.491 1.00 32.46 ? 269 ASP B C 1 ATOM 6144 O O . ASP B 1 269 ? -58.325 -19.569 262.590 1.00 32.41 ? 269 ASP B O 1 ATOM 6145 C CB . ASP B 1 269 ? -59.488 -20.769 265.393 1.00 31.74 ? 269 ASP B CB 1 ATOM 6146 C CG . ASP B 1 269 ? -58.811 -21.468 266.552 1.00 30.55 ? 269 ASP B CG 1 ATOM 6147 O OD1 . ASP B 1 269 ? -58.035 -20.806 267.272 1.00 25.58 ? 269 ASP B OD1 1 ATOM 6148 O OD2 . ASP B 1 269 ? -59.052 -22.678 266.741 1.00 43.28 ? 269 ASP B OD2 1 ATOM 6149 N N . PRO B 1 270 ? -60.185 -18.472 263.189 1.00 30.04 ? 270 PRO B N 1 ATOM 6150 C CA . PRO B 1 270 ? -60.469 -18.153 261.779 1.00 29.15 ? 270 PRO B CA 1 ATOM 6151 C C . PRO B 1 270 ? -59.423 -17.266 261.126 1.00 30.31 ? 270 PRO B C 1 ATOM 6152 O O . PRO B 1 270 ? -59.384 -17.190 259.892 1.00 34.04 ? 270 PRO B O 1 ATOM 6153 C CB . PRO B 1 270 ? -61.832 -17.451 261.843 1.00 33.32 ? 270 PRO B CB 1 ATOM 6154 C CG . PRO B 1 270 ? -62.445 -17.932 263.104 1.00 44.51 ? 270 PRO B CG 1 ATOM 6155 C CD . PRO B 1 270 ? -61.305 -18.075 264.062 1.00 31.11 ? 270 PRO B CD 1 ATOM 6156 N N . PHE B 1 271 ? -58.576 -16.595 261.910 1.00 33.09 ? 271 PHE B N 1 ATOM 6157 C CA . PHE B 1 271 ? -57.580 -15.698 261.334 1.00 34.34 ? 271 PHE B CA 1 ATOM 6158 C C . PHE B 1 271 ? -56.543 -16.459 260.517 1.00 35.11 ? 271 PHE B C 1 ATOM 6159 O O . PHE B 1 271 ? -56.107 -15.985 259.461 1.00 40.26 ? 271 PHE B O 1 ATOM 6160 C CB . PHE B 1 271 ? -56.897 -14.897 262.442 1.00 33.43 ? 271 PHE B CB 1 ATOM 6161 C CG . PHE B 1 271 ? -57.737 -13.785 262.997 1.00 29.26 ? 271 PHE B CG 1 ATOM 6162 C CD1 . PHE B 1 271 ? -58.442 -12.943 262.154 1.00 28.09 ? 271 PHE B CD1 1 ATOM 6163 C CD2 . PHE B 1 271 ? -57.822 -13.581 264.363 1.00 29.58 ? 271 PHE B CD2 1 ATOM 6164 C CE1 . PHE B 1 271 ? -59.214 -11.918 262.664 1.00 28.40 ? 271 PHE B CE1 1 ATOM 6165 C CE2 . PHE B 1 271 ? -58.593 -12.558 264.879 1.00 24.69 ? 271 PHE B CE2 1 ATOM 6166 C CZ . PHE B 1 271 ? -59.290 -11.726 264.028 1.00 26.13 ? 271 PHE B CZ 1 ATOM 6167 N N . TYR B 1 272 ? -56.135 -17.640 260.988 1.00 33.85 ? 272 TYR B N 1 ATOM 6168 C CA . TYR B 1 272 ? -55.073 -18.387 260.322 1.00 37.81 ? 272 TYR B CA 1 ATOM 6169 C C . TYR B 1 272 ? -55.452 -18.812 258.910 1.00 43.28 ? 272 TYR B C 1 ATOM 6170 O O . TYR B 1 272 ? -54.562 -19.029 258.081 1.00 49.46 ? 272 TYR B O 1 ATOM 6171 C CB . TYR B 1 272 ? -54.696 -19.618 261.149 1.00 38.30 ? 272 TYR B CB 1 ATOM 6172 C CG . TYR B 1 272 ? -54.216 -19.300 262.547 1.00 35.05 ? 272 TYR B CG 1 ATOM 6173 C CD1 . TYR B 1 272 ? -55.109 -19.209 263.605 1.00 35.52 ? 272 TYR B CD1 1 ATOM 6174 C CD2 . TYR B 1 272 ? -52.868 -19.094 262.808 1.00 42.73 ? 272 TYR B CD2 1 ATOM 6175 C CE1 . TYR B 1 272 ? -54.674 -18.918 264.884 1.00 36.11 ? 272 TYR B CE1 1 ATOM 6176 C CE2 . TYR B 1 272 ? -52.424 -18.803 264.083 1.00 41.22 ? 272 TYR B CE2 1 ATOM 6177 C CZ . TYR B 1 272 ? -53.331 -18.717 265.117 1.00 38.13 ? 272 TYR B CZ 1 ATOM 6178 O OH . TYR B 1 272 ? -52.894 -18.428 266.389 1.00 39.03 ? 272 TYR B OH 1 ATOM 6179 N N . PHE B 1 273 ? -56.744 -18.936 258.617 1.00 40.56 ? 273 PHE B N 1 ATOM 6180 C CA . PHE B 1 273 ? -57.204 -19.352 257.299 1.00 38.15 ? 273 PHE B CA 1 ATOM 6181 C C . PHE B 1 273 ? -57.398 -18.185 256.342 1.00 35.34 ? 273 PHE B C 1 ATOM 6182 O O . PHE B 1 273 ? -57.716 -18.412 255.170 1.00 35.35 ? 273 PHE B O 1 ATOM 6183 C CB . PHE B 1 273 ? -58.516 -20.131 257.422 1.00 36.17 ? 273 PHE B CB 1 ATOM 6184 C CG . PHE B 1 273 ? -58.421 -21.340 258.302 1.00 34.17 ? 273 PHE B CG 1 ATOM 6185 C CD1 . PHE B 1 273 ? -57.958 -22.543 257.798 1.00 39.43 ? 273 PHE B CD1 1 ATOM 6186 C CD2 . PHE B 1 273 ? -58.791 -21.274 259.634 1.00 32.23 ? 273 PHE B CD2 1 ATOM 6187 C CE1 . PHE B 1 273 ? -57.868 -23.659 258.606 1.00 53.91 ? 273 PHE B CE1 1 ATOM 6188 C CE2 . PHE B 1 273 ? -58.704 -22.385 260.447 1.00 33.94 ? 273 PHE B CE2 1 ATOM 6189 C CZ . PHE B 1 273 ? -58.241 -23.579 259.932 1.00 40.68 ? 273 PHE B CZ 1 ATOM 6190 N N . MET B 1 274 ? -57.213 -16.951 256.804 1.00 34.80 ? 274 MET B N 1 ATOM 6191 C CA . MET B 1 274 ? -57.437 -15.777 255.971 1.00 37.92 ? 274 MET B CA 1 ATOM 6192 C C . MET B 1 274 ? -56.310 -15.521 254.979 1.00 44.34 ? 274 MET B C 1 ATOM 6193 O O . MET B 1 274 ? -56.300 -14.463 254.340 1.00 51.97 ? 274 MET B O 1 ATOM 6194 C CB . MET B 1 274 ? -57.659 -14.542 256.848 1.00 37.35 ? 274 MET B CB 1 ATOM 6195 C CG . MET B 1 274 ? -58.885 -14.652 257.737 1.00 40.45 ? 274 MET B CG 1 ATOM 6196 S SD . MET B 1 274 ? -59.335 -13.106 258.541 1.00 33.90 ? 274 MET B SD 1 ATOM 6197 C CE . MET B 1 274 ? -60.692 -13.657 259.571 1.00 32.92 ? 274 MET B CE 1 ATOM 6198 N N . HIS B 1 275 ? -55.363 -16.452 254.833 1.00 44.05 ? 275 HIS B N 1 ATOM 6199 C CA . HIS B 1 275 ? -54.411 -16.346 253.734 1.00 46.48 ? 275 HIS B CA 1 ATOM 6200 C C . HIS B 1 275 ? -55.111 -16.500 252.391 1.00 45.78 ? 275 HIS B C 1 ATOM 6201 O O . HIS B 1 275 ? -54.637 -15.971 251.379 1.00 47.27 ? 275 HIS B O 1 ATOM 6202 C CB . HIS B 1 275 ? -53.300 -17.386 253.887 1.00 47.49 ? 275 HIS B CB 1 ATOM 6203 C CG . HIS B 1 275 ? -53.793 -18.798 253.939 1.00 55.17 ? 275 HIS B CG 1 ATOM 6204 N ND1 . HIS B 1 275 ? -54.167 -19.413 255.115 1.00 69.29 ? 275 HIS B ND1 1 ATOM 6205 C CD2 . HIS B 1 275 ? -53.966 -19.718 252.962 1.00 50.14 ? 275 HIS B CD2 1 ATOM 6206 C CE1 . HIS B 1 275 ? -54.553 -20.650 254.858 1.00 48.91 ? 275 HIS B CE1 1 ATOM 6207 N NE2 . HIS B 1 275 ? -54.441 -20.860 253.559 1.00 50.17 ? 275 HIS B NE2 1 ATOM 6208 N N . ASP B 1 276 ? -56.234 -17.214 252.365 1.00 44.99 ? 276 ASP B N 1 ATOM 6209 C CA . ASP B 1 276 ? -57.092 -17.223 251.189 1.00 46.22 ? 276 ASP B CA 1 ATOM 6210 C C . ASP B 1 276 ? -57.668 -15.831 250.966 1.00 49.51 ? 276 ASP B C 1 ATOM 6211 O O . ASP B 1 276 ? -58.185 -15.203 251.895 1.00 51.55 ? 276 ASP B O 1 ATOM 6212 C CB . ASP B 1 276 ? -58.217 -18.243 251.363 1.00 47.12 ? 276 ASP B CB 1 ATOM 6213 C CG . ASP B 1 276 ? -58.948 -18.535 250.066 1.00 47.23 ? 276 ASP B CG 1 ATOM 6214 O OD1 . ASP B 1 276 ? -58.613 -17.914 249.036 1.00 53.77 ? 276 ASP B OD1 1 ATOM 6215 O OD2 . ASP B 1 276 ? -59.863 -19.383 250.078 1.00 46.18 ? 276 ASP B OD2 1 ATOM 6216 N N . VAL B 1 277 ? -57.577 -15.347 249.725 1.00 54.78 ? 277 VAL B N 1 ATOM 6217 C CA . VAL B 1 277 ? -58.020 -13.990 249.434 1.00 54.54 ? 277 VAL B CA 1 ATOM 6218 C C . VAL B 1 277 ? -59.538 -13.875 249.414 1.00 52.87 ? 277 VAL B C 1 ATOM 6219 O O . VAL B 1 277 ? -60.071 -12.777 249.610 1.00 52.25 ? 277 VAL B O 1 ATOM 6220 C CB . VAL B 1 277 ? -57.421 -13.502 248.101 1.00 61.40 ? 277 VAL B CB 1 ATOM 6221 C CG1 . VAL B 1 277 ? -55.929 -13.794 248.053 1.00 62.21 ? 277 VAL B CG1 1 ATOM 6222 C CG2 . VAL B 1 277 ? -58.131 -14.147 246.922 1.00 91.80 ? 277 VAL B CG2 1 ATOM 6223 N N . GLU B 1 278 ? -60.255 -14.978 249.193 1.00 59.35 ? 278 GLU B N 1 ATOM 6224 C CA . GLU B 1 278 ? -61.707 -14.933 249.090 1.00 56.68 ? 278 GLU B CA 1 ATOM 6225 C C . GLU B 1 278 ? -62.418 -15.304 250.385 1.00 51.85 ? 278 GLU B C 1 ATOM 6226 O O . GLU B 1 278 ? -63.635 -15.119 250.474 1.00 61.66 ? 278 GLU B O 1 ATOM 6227 C CB . GLU B 1 278 ? -62.191 -15.840 247.954 1.00 64.25 ? 278 GLU B CB 1 ATOM 6228 C CG . GLU B 1 278 ? -62.910 -15.075 246.853 1.00 80.06 ? 278 GLU B CG 1 ATOM 6229 C CD . GLU B 1 278 ? -63.011 -15.854 245.558 1.00 100.68 ? 278 GLU B CD 1 ATOM 6230 O OE1 . GLU B 1 278 ? -63.381 -17.045 245.603 1.00 82.68 ? 278 GLU B OE1 1 ATOM 6231 O OE2 . GLU B 1 278 ? -62.719 -15.270 244.493 1.00 103.03 ? 278 GLU B OE2 1 ATOM 6232 N N . LYS B 1 279 ? -61.701 -15.824 251.380 1.00 48.83 ? 279 LYS B N 1 ATOM 6233 C CA . LYS B 1 279 ? -62.234 -15.927 252.731 1.00 45.43 ? 279 LYS B CA 1 ATOM 6234 C C . LYS B 1 279 ? -61.770 -14.787 253.626 1.00 42.97 ? 279 LYS B C 1 ATOM 6235 O O . LYS B 1 279 ? -62.230 -14.688 254.768 1.00 44.85 ? 279 LYS B O 1 ATOM 6236 C CB . LYS B 1 279 ? -61.852 -17.270 253.368 1.00 46.20 ? 279 LYS B CB 1 ATOM 6237 C CG . LYS B 1 279 ? -62.095 -18.475 252.475 1.00 50.87 ? 279 LYS B CG 1 ATOM 6238 C CD . LYS B 1 279 ? -61.937 -19.774 253.249 1.00 52.40 ? 279 LYS B CD 1 ATOM 6239 C CE . LYS B 1 279 ? -61.584 -20.934 252.332 1.00 70.52 ? 279 LYS B CE 1 ATOM 6240 N NZ . LYS B 1 279 ? -61.468 -22.218 253.079 1.00 48.60 ? 279 LYS B NZ 1 ATOM 6241 N N . ARG B 1 280 ? -60.877 -13.929 253.134 1.00 44.69 ? 280 ARG B N 1 ATOM 6242 C CA . ARG B 1 280 ? -60.441 -12.741 253.855 1.00 42.29 ? 280 ARG B CA 1 ATOM 6243 C C . ARG B 1 280 ? -61.305 -11.530 253.525 1.00 41.63 ? 280 ARG B C 1 ATOM 6244 O O . ARG B 1 280 ? -61.803 -10.854 254.430 1.00 43.21 ? 280 ARG B O 1 ATOM 6245 C CB . ARG B 1 280 ? -58.976 -12.439 253.532 1.00 48.50 ? 280 ARG B CB 1 ATOM 6246 C CG . ARG B 1 280 ? -58.394 -11.272 254.307 1.00 46.77 ? 280 ARG B CG 1 ATOM 6247 C CD . ARG B 1 280 ? -56.937 -11.036 253.943 1.00 51.50 ? 280 ARG B CD 1 ATOM 6248 N NE . ARG B 1 280 ? -56.792 -10.674 252.535 1.00 52.02 ? 280 ARG B NE 1 ATOM 6249 C CZ . ARG B 1 280 ? -56.417 -11.519 251.581 1.00 73.25 ? 280 ARG B CZ 1 ATOM 6250 N NH1 . ARG B 1 280 ? -56.128 -12.778 251.882 1.00 57.24 ? 280 ARG B NH1 1 ATOM 6251 N NH2 . ARG B 1 280 ? -56.323 -11.103 250.325 1.00 80.28 ? 280 ARG B NH2 1 ATOM 6252 N N . ASN B 1 281 ? -61.489 -11.242 252.233 1.00 44.18 ? 281 ASN B N 1 ATOM 6253 C CA . ASN B 1 281 ? -62.337 -10.122 251.845 1.00 44.26 ? 281 ASN B CA 1 ATOM 6254 C C . ASN B 1 281 ? -63.774 -10.324 252.298 1.00 43.78 ? 281 ASN B C 1 ATOM 6255 O O . ASN B 1 281 ? -64.506 -9.342 252.462 1.00 48.52 ? 281 ASN B O 1 ATOM 6256 C CB . ASN B 1 281 ? -62.285 -9.906 250.331 1.00 45.53 ? 281 ASN B CB 1 ATOM 6257 C CG . ASN B 1 281 ? -62.757 -11.114 249.553 1.00 52.33 ? 281 ASN B CG 1 ATOM 6258 O OD1 . ASN B 1 281 ? -62.927 -12.198 250.109 1.00 86.32 ? 281 ASN B OD1 1 ATOM 6259 N ND2 . ASN B 1 281 ? -62.971 -10.934 248.254 1.00 50.05 ? 281 ASN B ND2 1 ATOM 6260 N N . VAL B 1 282 ? -64.195 -11.574 252.498 1.00 45.13 ? 282 VAL B N 1 ATOM 6261 C CA . VAL B 1 282 ? -65.473 -11.828 253.157 1.00 43.01 ? 282 VAL B CA 1 ATOM 6262 C C . VAL B 1 282 ? -65.462 -11.241 254.561 1.00 41.41 ? 282 VAL B C 1 ATOM 6263 O O . VAL B 1 282 ? -66.354 -10.475 254.939 1.00 48.38 ? 282 VAL B O 1 ATOM 6264 C CB . VAL B 1 282 ? -65.779 -13.336 253.178 1.00 47.60 ? 282 VAL B CB 1 ATOM 6265 C CG1 . VAL B 1 282 ? -66.893 -13.634 254.164 1.00 42.94 ? 282 VAL B CG1 1 ATOM 6266 C CG2 . VAL B 1 282 ? -66.174 -13.811 251.793 1.00 59.87 ? 282 VAL B CG2 1 ATOM 6267 N N . PHE B 1 283 ? -64.436 -11.575 255.348 1.00 40.65 ? 283 PHE B N 1 ATOM 6268 C CA . PHE B 1 283 ? -64.361 -11.094 256.725 1.00 38.30 ? 283 PHE B CA 1 ATOM 6269 C C . PHE B 1 283 ? -64.324 -9.572 256.793 1.00 40.14 ? 283 PHE B C 1 ATOM 6270 O O . PHE B 1 283 ? -64.895 -8.972 257.711 1.00 45.96 ? 283 PHE B O 1 ATOM 6271 C CB . PHE B 1 283 ? -63.132 -11.686 257.413 1.00 43.90 ? 283 PHE B CB 1 ATOM 6272 C CG . PHE B 1 283 ? -62.748 -10.977 258.678 1.00 32.55 ? 283 PHE B CG 1 ATOM 6273 C CD1 . PHE B 1 283 ? -63.491 -11.141 259.834 1.00 30.51 ? 283 PHE B CD1 1 ATOM 6274 C CD2 . PHE B 1 283 ? -61.641 -10.147 258.711 1.00 35.85 ? 283 PHE B CD2 1 ATOM 6275 C CE1 . PHE B 1 283 ? -63.137 -10.488 260.997 1.00 29.80 ? 283 PHE B CE1 1 ATOM 6276 C CE2 . PHE B 1 283 ? -61.283 -9.492 259.871 1.00 34.03 ? 283 PHE B CE2 1 ATOM 6277 C CZ . PHE B 1 283 ? -62.032 -9.663 261.016 1.00 30.14 ? 283 PHE B CZ 1 ATOM 6278 N N . VAL B 1 284 ? -63.658 -8.931 255.832 1.00 40.78 ? 284 VAL B N 1 ATOM 6279 C CA . VAL B 1 284 ? -63.462 -7.486 255.900 1.00 42.68 ? 284 VAL B CA 1 ATOM 6280 C C . VAL B 1 284 ? -64.782 -6.743 255.727 1.00 44.24 ? 284 VAL B C 1 ATOM 6281 O O . VAL B 1 284 ? -64.945 -5.624 256.231 1.00 66.75 ? 284 VAL B O 1 ATOM 6282 C CB . VAL B 1 284 ? -62.418 -7.060 254.847 1.00 56.69 ? 284 VAL B CB 1 ATOM 6283 C CG1 . VAL B 1 284 ? -62.268 -5.545 254.796 1.00 45.72 ? 284 VAL B CG1 1 ATOM 6284 C CG2 . VAL B 1 284 ? -61.079 -7.725 255.129 1.00 54.94 ? 284 VAL B CG2 1 ATOM 6285 N N . ASP B 1 285 ? -65.759 -7.360 255.060 1.00 41.91 ? 285 ASP B N 1 ATOM 6286 C CA . ASP B 1 285 ? -66.915 -6.606 254.583 1.00 43.28 ? 285 ASP B CA 1 ATOM 6287 C C . ASP B 1 285 ? -67.880 -6.248 255.711 1.00 44.80 ? 285 ASP B C 1 ATOM 6288 O O . ASP B 1 285 ? -68.475 -5.165 255.693 1.00 45.05 ? 285 ASP B O 1 ATOM 6289 C CB . ASP B 1 285 ? -67.629 -7.390 253.485 1.00 42.22 ? 285 ASP B CB 1 ATOM 6290 C CG . ASP B 1 285 ? -66.867 -7.372 252.176 1.00 40.80 ? 285 ASP B CG 1 ATOM 6291 O OD1 . ASP B 1 285 ? -65.722 -6.874 252.167 1.00 48.38 ? 285 ASP B OD1 1 ATOM 6292 O OD2 . ASP B 1 285 ? -67.409 -7.850 251.160 1.00 35.97 ? 285 ASP B OD2 1 ATOM 6293 N N . SER B 1 286 ? -68.075 -7.137 256.689 1.00 44.18 ? 286 SER B N 1 ATOM 6294 C CA . SER B 1 286 ? -68.949 -6.771 257.803 1.00 47.26 ? 286 SER B CA 1 ATOM 6295 C C . SER B 1 286 ? -68.332 -5.702 258.688 1.00 44.86 ? 286 SER B C 1 ATOM 6296 O O . SER B 1 286 ? -69.060 -4.871 259.239 1.00 42.80 ? 286 SER B O 1 ATOM 6297 C CB . SER B 1 286 ? -69.336 -7.988 258.637 1.00 51.49 ? 286 SER B CB 1 ATOM 6298 O OG . SER B 1 286 ? -70.525 -8.569 258.129 1.00 100.21 ? 286 SER B OG 1 ATOM 6299 N N . VAL B 1 287 ? -67.006 -5.680 258.827 1.00 45.23 ? 287 VAL B N 1 ATOM 6300 C CA . VAL B 1 287 ? -66.388 -4.573 259.546 1.00 48.18 ? 287 VAL B CA 1 ATOM 6301 C C . VAL B 1 287 ? -66.800 -3.238 258.941 1.00 65.36 ? 287 VAL B C 1 ATOM 6302 O O . VAL B 1 287 ? -66.748 -2.206 259.615 1.00 85.46 ? 287 VAL B O 1 ATOM 6303 C CB . VAL B 1 287 ? -64.858 -4.751 259.570 1.00 64.52 ? 287 VAL B CB 1 ATOM 6304 C CG1 . VAL B 1 287 ? -64.236 -3.764 260.519 1.00 68.12 ? 287 VAL B CG1 1 ATOM 6305 C CG2 . VAL B 1 287 ? -64.501 -6.177 259.969 1.00 52.83 ? 287 VAL B CG2 1 ATOM 6306 N N . LYS B 1 288 ? -67.247 -3.244 257.687 1.00 47.28 ? 288 LYS B N 1 ATOM 6307 C CA . LYS B 1 288 ? -67.963 -2.128 257.092 1.00 45.51 ? 288 LYS B CA 1 ATOM 6308 C C . LYS B 1 288 ? -69.457 -2.196 257.382 1.00 42.30 ? 288 LYS B C 1 ATOM 6309 O O . LYS B 1 288 ? -70.092 -1.158 257.580 1.00 48.99 ? 288 LYS B O 1 ATOM 6310 C CB . LYS B 1 288 ? -67.723 -2.108 255.580 1.00 48.62 ? 288 LYS B CB 1 ATOM 6311 C CG . LYS B 1 288 ? -68.538 -1.097 254.777 1.00 43.48 ? 288 LYS B CG 1 ATOM 6312 C CD . LYS B 1 288 ? -68.035 -1.042 253.344 1.00 41.14 ? 288 LYS B CD 1 ATOM 6313 C CE . LYS B 1 288 ? -68.699 0.070 252.568 1.00 50.30 ? 288 LYS B CE 1 ATOM 6314 N NZ . LYS B 1 288 ? -68.071 0.269 251.239 1.00 67.92 ? 288 LYS B NZ 1 ATOM 6315 N N . GLU B 1 289 ? -70.027 -3.402 257.423 1.00 42.39 ? 289 GLU B N 1 ATOM 6316 C CA . GLU B 1 289 ? -71.460 -3.594 257.627 1.00 39.58 ? 289 GLU B CA 1 ATOM 6317 C C . GLU B 1 289 ? -71.837 -3.659 259.105 1.00 35.86 ? 289 GLU B C 1 ATOM 6318 O O . GLU B 1 289 ? -72.870 -3.111 259.504 1.00 49.09 ? 289 GLU B O 1 ATOM 6319 C CB . GLU B 1 289 ? -71.916 -4.873 256.918 1.00 41.57 ? 289 GLU B CB 1 ATOM 6320 C CG . GLU B 1 289 ? -73.386 -5.212 257.092 1.00 42.47 ? 289 GLU B CG 1 ATOM 6321 C CD . GLU B 1 289 ? -74.270 -4.526 256.068 1.00 44.05 ? 289 GLU B CD 1 ATOM 6322 O OE1 . GLU B 1 289 ? -73.747 -4.122 255.010 1.00 50.26 ? 289 GLU B OE1 1 ATOM 6323 O OE2 . GLU B 1 289 ? -75.488 -4.394 256.315 1.00 46.27 ? 289 GLU B OE2 1 ATOM 6324 N N . PHE B 1 290 ? -71.023 -4.336 259.920 1.00 35.40 ? 290 PHE B N 1 ATOM 6325 C CA . PHE B 1 290 ? -71.251 -4.374 261.363 1.00 33.89 ? 290 PHE B CA 1 ATOM 6326 C C . PHE B 1 290 ? -71.258 -2.971 261.956 1.00 31.15 ? 290 PHE B C 1 ATOM 6327 O O . PHE B 1 290 ? -72.007 -2.689 262.898 1.00 35.39 ? 290 PHE B O 1 ATOM 6328 C CB . PHE B 1 290 ? -70.173 -5.239 262.026 1.00 35.09 ? 290 PHE B CB 1 ATOM 6329 C CG . PHE B 1 290 ? -70.459 -5.610 263.454 1.00 28.08 ? 290 PHE B CG 1 ATOM 6330 C CD1 . PHE B 1 290 ? -70.149 -4.740 264.486 1.00 28.19 ? 290 PHE B CD1 1 ATOM 6331 C CD2 . PHE B 1 290 ? -71.001 -6.844 263.766 1.00 30.54 ? 290 PHE B CD2 1 ATOM 6332 C CE1 . PHE B 1 290 ? -70.396 -5.084 265.799 1.00 28.39 ? 290 PHE B CE1 1 ATOM 6333 C CE2 . PHE B 1 290 ? -71.251 -7.194 265.080 1.00 35.98 ? 290 PHE B CE2 1 ATOM 6334 C CZ . PHE B 1 290 ? -70.948 -6.313 266.097 1.00 28.53 ? 290 PHE B CZ 1 ATOM 6335 N N . LEU B 1 291 ? -70.433 -2.074 261.413 1.00 30.60 ? 291 LEU B N 1 ATOM 6336 C CA . LEU B 1 291 ? -70.362 -0.714 261.932 1.00 29.13 ? 291 LEU B CA 1 ATOM 6337 C C . LEU B 1 291 ? -71.503 0.166 261.441 1.00 27.81 ? 291 LEU B C 1 ATOM 6338 O O . LEU B 1 291 ? -71.830 1.155 262.106 1.00 28.01 ? 291 LEU B O 1 ATOM 6339 C CB . LEU B 1 291 ? -69.019 -0.078 261.567 1.00 33.52 ? 291 LEU B CB 1 ATOM 6340 C CG . LEU B 1 291 ? -67.796 -0.715 262.231 1.00 33.46 ? 291 LEU B CG 1 ATOM 6341 C CD1 . LEU B 1 291 ? -66.516 0.024 261.862 1.00 36.37 ? 291 LEU B CD1 1 ATOM 6342 C CD2 . LEU B 1 291 ? -67.966 -0.787 263.736 1.00 27.48 ? 291 LEU B CD2 1 ATOM 6343 N N . GLN B 1 292 ? -72.108 -0.157 260.295 1.00 25.77 ? 292 GLN B N 1 ATOM 6344 C CA . GLN B 1 292 ? -73.319 0.548 259.888 1.00 25.99 ? 292 GLN B CA 1 ATOM 6345 C C . GLN B 1 292 ? -74.530 0.062 260.674 1.00 27.67 ? 292 GLN B C 1 ATOM 6346 O O . GLN B 1 292 ? -75.421 0.854 260.998 1.00 35.63 ? 292 GLN B O 1 ATOM 6347 C CB . GLN B 1 292 ? -73.558 0.384 258.387 1.00 30.35 ? 292 GLN B CB 1 ATOM 6348 C CG . GLN B 1 292 ? -72.385 0.804 257.525 1.00 36.82 ? 292 GLN B CG 1 ATOM 6349 C CD . GLN B 1 292 ? -72.593 0.480 256.059 1.00 39.19 ? 292 GLN B CD 1 ATOM 6350 O OE1 . GLN B 1 292 ? -73.707 0.186 255.629 1.00 49.27 ? 292 GLN B OE1 1 ATOM 6351 N NE2 . GLN B 1 292 ? -71.516 0.532 255.283 1.00 43.35 ? 292 GLN B NE2 1 ATOM 6352 N N . VAL B 1 293 ? -74.585 -1.235 260.980 1.00 27.33 ? 293 VAL B N 1 ATOM 6353 C CA . VAL B 1 293 ? -75.633 -1.739 261.860 1.00 25.80 ? 293 VAL B CA 1 ATOM 6354 C C . VAL B 1 293 ? -75.435 -1.204 263.271 1.00 23.91 ? 293 VAL B C 1 ATOM 6355 O O . VAL B 1 293 ? -76.352 -0.637 263.874 1.00 22.94 ? 293 VAL B O 1 ATOM 6356 C CB . VAL B 1 293 ? -75.661 -3.278 261.837 1.00 25.81 ? 293 VAL B CB 1 ATOM 6357 C CG1 . VAL B 1 293 ? -76.498 -3.810 262.991 1.00 23.60 ? 293 VAL B CG1 1 ATOM 6358 C CG2 . VAL B 1 293 ? -76.198 -3.778 260.506 1.00 29.32 ? 293 VAL B CG2 1 ATOM 6359 N N . TRP B 1 294 ? -74.231 -1.363 263.811 1.00 25.05 ? 294 TRP B N 1 ATOM 6360 C CA . TRP B 1 294 ? -73.881 -0.887 265.146 1.00 24.29 ? 294 TRP B CA 1 ATOM 6361 C C . TRP B 1 294 ? -72.999 0.346 264.982 1.00 25.34 ? 294 TRP B C 1 ATOM 6362 O O . TRP B 1 294 ? -71.784 0.234 264.800 1.00 29.95 ? 294 TRP B O 1 ATOM 6363 C CB . TRP B 1 294 ? -73.185 -1.983 265.943 1.00 25.66 ? 294 TRP B CB 1 ATOM 6364 C CG . TRP B 1 294 ? -73.914 -3.285 265.882 1.00 24.85 ? 294 TRP B CG 1 ATOM 6365 C CD1 . TRP B 1 294 ? -73.587 -4.373 265.128 1.00 25.46 ? 294 TRP B CD1 1 ATOM 6366 C CD2 . TRP B 1 294 ? -75.111 -3.630 266.587 1.00 23.58 ? 294 TRP B CD2 1 ATOM 6367 N NE1 . TRP B 1 294 ? -74.499 -5.380 265.329 1.00 37.60 ? 294 TRP B NE1 1 ATOM 6368 C CE2 . TRP B 1 294 ? -75.446 -4.948 266.220 1.00 26.21 ? 294 TRP B CE2 1 ATOM 6369 C CE3 . TRP B 1 294 ? -75.929 -2.955 267.497 1.00 22.37 ? 294 TRP B CE3 1 ATOM 6370 C CZ2 . TRP B 1 294 ? -76.563 -5.603 266.731 1.00 27.51 ? 294 TRP B CZ2 1 ATOM 6371 C CZ3 . TRP B 1 294 ? -77.037 -3.607 268.002 1.00 21.78 ? 294 TRP B CZ3 1 ATOM 6372 C CH2 . TRP B 1 294 ? -77.344 -4.917 267.618 1.00 26.74 ? 294 TRP B CH2 1 ATOM 6373 N N . LYS B 1 295 ? -73.620 1.523 265.051 1.00 26.52 ? 295 LYS B N 1 ATOM 6374 C CA . LYS B 1 295 ? -72.925 2.776 264.797 1.00 25.39 ? 295 LYS B CA 1 ATOM 6375 C C . LYS B 1 295 ? -72.182 3.309 266.014 1.00 21.72 ? 295 LYS B C 1 ATOM 6376 O O . LYS B 1 295 ? -71.355 4.214 265.865 1.00 24.09 ? 295 LYS B O 1 ATOM 6377 C CB . LYS B 1 295 ? -73.924 3.824 264.301 1.00 19.26 ? 295 LYS B CB 1 ATOM 6378 C CG . LYS B 1 295 ? -74.675 3.401 263.047 1.00 22.00 ? 295 LYS B CG 1 ATOM 6379 C CD . LYS B 1 295 ? -75.788 4.374 262.698 1.00 20.57 ? 295 LYS B CD 1 ATOM 6380 C CE . LYS B 1 295 ? -76.541 3.919 261.458 1.00 20.03 ? 295 LYS B CE 1 ATOM 6381 N NZ . LYS B 1 295 ? -77.737 4.762 261.185 1.00 18.70 ? 295 LYS B NZ 1 ATOM 6382 N N . PHE B 1 296 ? -72.447 2.772 267.207 1.00 20.82 ? 296 PHE B N 1 ATOM 6383 C CA . PHE B 1 296 ? -71.812 3.281 268.416 1.00 21.55 ? 296 PHE B CA 1 ATOM 6384 C C . PHE B 1 296 ? -70.348 2.877 268.536 1.00 21.82 ? 296 PHE B C 1 ATOM 6385 O O . PHE B 1 296 ? -69.655 3.397 269.416 1.00 19.44 ? 296 PHE B O 1 ATOM 6386 C CB . PHE B 1 296 ? -72.590 2.822 269.652 1.00 30.13 ? 296 PHE B CB 1 ATOM 6387 C CG . PHE B 1 296 ? -72.581 1.335 269.863 1.00 24.75 ? 296 PHE B CG 1 ATOM 6388 C CD1 . PHE B 1 296 ? -73.484 0.523 269.199 1.00 24.18 ? 296 PHE B CD1 1 ATOM 6389 C CD2 . PHE B 1 296 ? -71.681 0.752 270.739 1.00 22.27 ? 296 PHE B CD2 1 ATOM 6390 C CE1 . PHE B 1 296 ? -73.483 -0.843 269.393 1.00 36.10 ? 296 PHE B CE1 1 ATOM 6391 C CE2 . PHE B 1 296 ? -71.675 -0.615 270.938 1.00 20.68 ? 296 PHE B CE2 1 ATOM 6392 C CZ . PHE B 1 296 ? -72.578 -1.413 270.264 1.00 31.66 ? 296 PHE B CZ 1 ATOM 6393 N N . PHE B 1 297 ? -69.866 1.973 267.689 1.00 20.75 ? 297 PHE B N 1 ATOM 6394 C CA . PHE B 1 297 ? -68.445 1.663 267.650 1.00 20.86 ? 297 PHE B CA 1 ATOM 6395 C C . PHE B 1 297 ? -67.705 2.705 266.819 1.00 22.09 ? 297 PHE B C 1 ATOM 6396 O O . PHE B 1 297 ? -68.233 3.240 265.841 1.00 23.13 ? 297 PHE B O 1 ATOM 6397 C CB . PHE B 1 297 ? -68.208 0.269 267.067 1.00 21.26 ? 297 PHE B CB 1 ATOM 6398 C CG . PHE B 1 297 ? -68.658 -0.854 267.960 1.00 21.66 ? 297 PHE B CG 1 ATOM 6399 C CD1 . PHE B 1 297 ? -68.082 -1.043 269.204 1.00 20.82 ? 297 PHE B CD1 1 ATOM 6400 C CD2 . PHE B 1 297 ? -69.645 -1.732 267.545 1.00 20.87 ? 297 PHE B CD2 1 ATOM 6401 C CE1 . PHE B 1 297 ? -68.490 -2.079 270.024 1.00 16.60 ? 297 PHE B CE1 1 ATOM 6402 C CE2 . PHE B 1 297 ? -70.056 -2.770 268.360 1.00 17.87 ? 297 PHE B CE2 1 ATOM 6403 C CZ . PHE B 1 297 ? -69.477 -2.944 269.601 1.00 16.22 ? 297 PHE B CZ 1 ATOM 6404 N N . ASP B 1 298 ? -66.465 2.991 267.218 1.00 22.59 ? 298 ASP B N 1 ATOM 6405 C CA . ASP B 1 298 ? -65.661 4.023 266.574 1.00 23.89 ? 298 ASP B CA 1 ATOM 6406 C C . ASP B 1 298 ? -64.462 3.464 265.819 1.00 24.03 ? 298 ASP B C 1 ATOM 6407 O O . ASP B 1 298 ? -63.568 4.231 265.447 1.00 29.05 ? 298 ASP B O 1 ATOM 6408 C CB . ASP B 1 298 ? -65.186 5.048 267.606 1.00 19.25 ? 298 ASP B CB 1 ATOM 6409 C CG . ASP B 1 298 ? -66.332 5.762 268.286 1.00 24.16 ? 298 ASP B CG 1 ATOM 6410 O OD1 . ASP B 1 298 ? -67.011 6.572 267.620 1.00 24.77 ? 298 ASP B OD1 1 ATOM 6411 O OD2 . ASP B 1 298 ? -66.554 5.515 269.490 1.00 43.11 ? 298 ASP B OD2 1 ATOM 6412 N N . GLY B 1 299 ? -64.415 2.157 265.582 1.00 20.64 ? 299 GLY B N 1 ATOM 6413 C CA . GLY B 1 299 ? -63.291 1.598 264.858 1.00 24.08 ? 299 GLY B CA 1 ATOM 6414 C C . GLY B 1 299 ? -63.214 0.087 264.859 1.00 35.86 ? 299 GLY B C 1 ATOM 6415 O O . GLY B 1 299 ? -64.237 -0.596 264.759 1.00 28.91 ? 299 GLY B O 1 ATOM 6416 N N . VAL B 1 300 ? -61.995 -0.448 264.930 1.00 30.69 ? 300 VAL B N 1 ATOM 6417 C CA . VAL B 1 300 ? -61.755 -1.887 264.939 1.00 21.80 ? 300 VAL B CA 1 ATOM 6418 C C . VAL B 1 300 ? -60.626 -2.182 265.915 1.00 23.66 ? 300 VAL B C 1 ATOM 6419 O O . VAL B 1 300 ? -59.685 -1.392 266.050 1.00 28.39 ? 300 VAL B O 1 ATOM 6420 C CB . VAL B 1 300 ? -61.385 -2.433 263.541 1.00 24.95 ? 300 VAL B CB 1 ATOM 6421 C CG1 . VAL B 1 300 ? -61.575 -3.944 263.487 1.00 22.86 ? 300 VAL B CG1 1 ATOM 6422 C CG2 . VAL B 1 300 ? -62.171 -1.742 262.444 1.00 32.85 ? 300 VAL B CG2 1 ATOM 6423 N N . ASP B 1 301 ? -60.717 -3.324 266.591 1.00 23.45 ? 301 ASP B N 1 ATOM 6424 C CA . ASP B 1 301 ? -59.616 -3.860 267.381 1.00 22.19 ? 301 ASP B CA 1 ATOM 6425 C C . ASP B 1 301 ? -59.373 -5.293 266.936 1.00 21.59 ? 301 ASP B C 1 ATOM 6426 O O . ASP B 1 301 ? -60.237 -6.156 267.119 1.00 22.57 ? 301 ASP B O 1 ATOM 6427 C CB . ASP B 1 301 ? -59.914 -3.803 268.881 1.00 23.24 ? 301 ASP B CB 1 ATOM 6428 C CG . ASP B 1 301 ? -58.706 -4.161 269.724 1.00 20.34 ? 301 ASP B CG 1 ATOM 6429 O OD1 . ASP B 1 301 ? -57.573 -3.864 269.292 1.00 19.63 ? 301 ASP B OD1 1 ATOM 6430 O OD2 . ASP B 1 301 ? -58.888 -4.740 270.815 1.00 18.25 ? 301 ASP B OD2 1 ATOM 6431 N N . VAL B 1 302 ? -58.208 -5.541 266.349 1.00 23.14 ? 302 VAL B N 1 ATOM 6432 C CA . VAL B 1 302 ? -57.856 -6.849 265.812 1.00 21.92 ? 302 VAL B CA 1 ATOM 6433 C C . VAL B 1 302 ? -57.051 -7.586 266.872 1.00 21.90 ? 302 VAL B C 1 ATOM 6434 O O . VAL B 1 302 ? -55.913 -7.213 267.174 1.00 22.37 ? 302 VAL B O 1 ATOM 6435 C CB . VAL B 1 302 ? -57.072 -6.727 264.499 1.00 19.90 ? 302 VAL B CB 1 ATOM 6436 C CG1 . VAL B 1 302 ? -56.770 -8.105 263.936 1.00 26.75 ? 302 VAL B CG1 1 ATOM 6437 C CG2 . VAL B 1 302 ? -57.849 -5.890 263.494 1.00 20.47 ? 302 VAL B CG2 1 ATOM 6438 N N . ASP B 1 303 ? -57.635 -8.638 267.441 1.00 20.83 ? 303 ASP B N 1 ATOM 6439 C CA . ASP B 1 303 ? -56.955 -9.409 268.473 1.00 21.39 ? 303 ASP B CA 1 ATOM 6440 C C . ASP B 1 303 ? -56.574 -10.793 267.964 1.00 25.37 ? 303 ASP B C 1 ATOM 6441 O O . ASP B 1 303 ? -56.996 -11.809 268.526 1.00 29.10 ? 303 ASP B O 1 ATOM 6442 C CB . ASP B 1 303 ? -57.831 -9.517 269.721 1.00 22.58 ? 303 ASP B CB 1 ATOM 6443 C CG . ASP B 1 303 ? -58.145 -8.164 270.328 1.00 22.57 ? 303 ASP B CG 1 ATOM 6444 O OD1 . ASP B 1 303 ? -57.363 -7.696 271.181 1.00 21.78 ? 303 ASP B OD1 1 ATOM 6445 O OD2 . ASP B 1 303 ? -59.168 -7.562 269.945 1.00 25.06 ? 303 ASP B OD2 1 ATOM 6446 N N . TRP B 1 304 ? -55.778 -10.840 266.897 1.00 32.99 ? 304 TRP B N 1 ATOM 6447 C CA . TRP B 1 304 ? -55.269 -12.101 266.369 1.00 31.32 ? 304 TRP B CA 1 ATOM 6448 C C . TRP B 1 304 ? -54.217 -12.646 267.326 1.00 34.83 ? 304 TRP B C 1 ATOM 6449 O O . TRP B 1 304 ? -53.142 -12.057 267.479 1.00 61.71 ? 304 TRP B O 1 ATOM 6450 C CB . TRP B 1 304 ? -54.695 -11.885 264.971 1.00 30.87 ? 304 TRP B CB 1 ATOM 6451 C CG . TRP B 1 304 ? -54.249 -13.135 264.257 1.00 32.94 ? 304 TRP B CG 1 ATOM 6452 C CD1 . TRP B 1 304 ? -54.118 -14.388 264.784 1.00 33.52 ? 304 TRP B CD1 1 ATOM 6453 C CD2 . TRP B 1 304 ? -53.883 -13.244 262.875 1.00 35.09 ? 304 TRP B CD2 1 ATOM 6454 N NE1 . TRP B 1 304 ? -53.688 -15.266 263.819 1.00 35.49 ? 304 TRP B NE1 1 ATOM 6455 C CE2 . TRP B 1 304 ? -53.537 -14.589 262.639 1.00 36.64 ? 304 TRP B CE2 1 ATOM 6456 C CE3 . TRP B 1 304 ? -53.814 -12.334 261.816 1.00 35.62 ? 304 TRP B CE3 1 ATOM 6457 C CZ2 . TRP B 1 304 ? -53.130 -15.045 261.387 1.00 42.17 ? 304 TRP B CZ2 1 ATOM 6458 C CZ3 . TRP B 1 304 ? -53.408 -12.789 260.575 1.00 36.33 ? 304 TRP B CZ3 1 ATOM 6459 C CH2 . TRP B 1 304 ? -53.072 -14.132 260.371 1.00 41.92 ? 304 TRP B CH2 1 ATOM 6460 N N . GLU B 1 305 ? -54.519 -13.768 267.970 1.00 30.08 ? 305 GLU B N 1 ATOM 6461 C CA . GLU B 1 305 ? -53.623 -14.331 268.972 1.00 32.02 ? 305 GLU B CA 1 ATOM 6462 C C . GLU B 1 305 ? -53.292 -15.796 268.702 1.00 39.60 ? 305 GLU B C 1 ATOM 6463 O O . GLU B 1 305 ? -54.059 -16.684 269.070 1.00 52.78 ? 305 GLU B O 1 ATOM 6464 C CB . GLU B 1 305 ? -54.234 -14.195 270.367 1.00 30.60 ? 305 GLU B CB 1 ATOM 6465 C CG . GLU B 1 305 ? -54.469 -12.763 270.812 1.00 30.06 ? 305 GLU B CG 1 ATOM 6466 C CD . GLU B 1 305 ? -55.027 -12.678 272.218 1.00 32.59 ? 305 GLU B CD 1 ATOM 6467 O OE1 . GLU B 1 305 ? -54.981 -13.696 272.940 1.00 45.63 ? 305 GLU B OE1 1 ATOM 6468 O OE2 . GLU B 1 305 ? -55.511 -11.593 272.602 1.00 35.79 ? 305 GLU B OE2 1 ATOM 6469 N N . PHE B 1 306 ? -52.154 -16.051 268.060 1.00 54.58 ? 306 PHE B N 1 ATOM 6470 C CA . PHE B 1 306 ? -51.277 -15.005 267.546 1.00 38.13 ? 306 PHE B CA 1 ATOM 6471 C C . PHE B 1 306 ? -50.902 -15.343 266.108 1.00 41.95 ? 306 PHE B C 1 ATOM 6472 O O . PHE B 1 306 ? -50.939 -16.509 265.718 1.00 58.57 ? 306 PHE B O 1 ATOM 6473 C CB . PHE B 1 306 ? -50.013 -14.867 268.402 1.00 39.65 ? 306 PHE B CB 1 ATOM 6474 C CG . PHE B 1 306 ? -50.284 -14.729 269.871 1.00 34.69 ? 306 PHE B CG 1 ATOM 6475 C CD1 . PHE B 1 306 ? -50.602 -13.498 270.418 1.00 34.83 ? 306 PHE B CD1 1 ATOM 6476 C CD2 . PHE B 1 306 ? -50.198 -15.827 270.709 1.00 37.10 ? 306 PHE B CD2 1 ATOM 6477 C CE1 . PHE B 1 306 ? -50.852 -13.371 271.769 1.00 34.07 ? 306 PHE B CE1 1 ATOM 6478 C CE2 . PHE B 1 306 ? -50.440 -15.703 272.062 1.00 40.41 ? 306 PHE B CE2 1 ATOM 6479 C CZ . PHE B 1 306 ? -50.766 -14.473 272.593 1.00 34.32 ? 306 PHE B CZ 1 ATOM 6480 N N . PRO B 1 307 ? -50.545 -14.334 265.312 1.00 39.20 ? 307 PRO B N 1 ATOM 6481 C CA . PRO B 1 307 ? -50.074 -14.623 263.952 1.00 40.81 ? 307 PRO B CA 1 ATOM 6482 C C . PRO B 1 307 ? -48.751 -15.369 263.976 1.00 43.28 ? 307 PRO B C 1 ATOM 6483 O O . PRO B 1 307 ? -47.708 -14.795 264.305 1.00 44.88 ? 307 PRO B O 1 ATOM 6484 C CB . PRO B 1 307 ? -49.938 -13.234 263.314 1.00 41.42 ? 307 PRO B CB 1 ATOM 6485 C CG . PRO B 1 307 ? -50.682 -12.297 264.221 1.00 40.77 ? 307 PRO B CG 1 ATOM 6486 C CD . PRO B 1 307 ? -50.590 -12.889 265.587 1.00 38.83 ? 307 PRO B CD 1 ATOM 6487 N N . GLY B 1 308 ? -48.789 -16.655 263.641 1.00 48.13 ? 308 GLY B N 1 ATOM 6488 C CA . GLY B 1 308 ? -47.623 -17.517 263.695 1.00 50.54 ? 308 GLY B CA 1 ATOM 6489 C C . GLY B 1 308 ? -47.775 -18.727 264.595 1.00 54.18 ? 308 GLY B C 1 ATOM 6490 O O . GLY B 1 308 ? -46.927 -19.630 264.535 1.00 54.81 ? 308 GLY B O 1 ATOM 6491 N N . GLY B 1 309 ? -48.811 -18.788 265.433 1.00 47.79 ? 309 GLY B N 1 ATOM 6492 C CA . GLY B 1 309 ? -49.027 -19.935 266.293 1.00 48.66 ? 309 GLY B CA 1 ATOM 6493 C C . GLY B 1 309 ? -49.114 -19.609 267.770 1.00 45.42 ? 309 GLY B C 1 ATOM 6494 O O . GLY B 1 309 ? -49.391 -18.467 268.149 1.00 46.22 ? 309 GLY B O 1 ATOM 6495 N N . LYS B 1 310 ? -48.894 -20.629 268.607 1.00 41.30 ? 310 LYS B N 1 ATOM 6496 C CA . LYS B 1 310 ? -48.860 -20.513 270.062 1.00 40.58 ? 310 LYS B CA 1 ATOM 6497 C C . LYS B 1 310 ? -50.244 -20.196 270.622 1.00 44.23 ? 310 LYS B C 1 ATOM 6498 O O . LYS B 1 310 ? -50.434 -20.162 271.842 1.00 42.05 ? 310 LYS B O 1 ATOM 6499 C CB . LYS B 1 310 ? -47.817 -19.466 270.496 1.00 42.29 ? 310 LYS B CB 1 ATOM 6500 C CG . LYS B 1 310 ? -47.642 -19.344 272.019 1.00 47.77 ? 310 LYS B CG 1 ATOM 6501 C CD . LYS B 1 310 ? -46.257 -18.916 272.437 1.00 77.61 ? 310 LYS B CD 1 ATOM 6502 C CE . LYS B 1 310 ? -46.155 -18.926 273.961 1.00 72.33 ? 310 LYS B CE 1 ATOM 6503 N NZ . LYS B 1 310 ? -47.260 -18.164 274.629 1.00 47.76 ? 310 LYS B NZ 1 ATOM 6504 N N . GLY B 1 311 ? -51.230 -20.021 269.743 1.00 41.88 ? 311 GLY B N 1 ATOM 6505 C CA . GLY B 1 311 ? -52.599 -19.799 270.165 1.00 37.94 ? 311 GLY B CA 1 ATOM 6506 C C . GLY B 1 311 ? -53.173 -20.950 270.966 1.00 45.56 ? 311 GLY B C 1 ATOM 6507 O O . GLY B 1 311 ? -52.477 -21.932 271.243 1.00 37.69 ? 311 GLY B O 1 ATOM 6508 N N . ALA B 1 312 ? -54.447 -20.838 271.345 1.00 34.95 ? 312 ALA B N 1 ATOM 6509 C CA . ALA B 1 312 ? -55.080 -21.894 272.125 1.00 31.31 ? 312 ALA B CA 1 ATOM 6510 C C . ALA B 1 312 ? -55.077 -23.222 271.381 1.00 31.64 ? 312 ALA B C 1 ATOM 6511 O O . ALA B 1 312 ? -55.046 -24.285 272.010 1.00 33.83 ? 312 ALA B O 1 ATOM 6512 C CB . ALA B 1 312 ? -56.507 -21.489 272.490 1.00 34.43 ? 312 ALA B CB 1 ATOM 6513 N N . ASN B 1 313 ? -55.100 -23.184 270.049 1.00 32.08 ? 313 ASN B N 1 ATOM 6514 C CA . ASN B 1 313 ? -55.072 -24.398 269.249 1.00 43.45 ? 313 ASN B CA 1 ATOM 6515 C C . ASN B 1 313 ? -53.656 -24.633 268.747 1.00 38.01 ? 313 ASN B C 1 ATOM 6516 O O . ASN B 1 313 ? -53.177 -23.868 267.896 1.00 39.27 ? 313 ASN B O 1 ATOM 6517 C CB . ASN B 1 313 ? -56.043 -24.291 268.075 1.00 45.63 ? 313 ASN B CB 1 ATOM 6518 C CG . ASN B 1 313 ? -56.339 -25.634 267.439 1.00 41.35 ? 313 ASN B CG 1 ATOM 6519 O OD1 . ASN B 1 313 ? -56.237 -26.676 268.086 1.00 58.02 ? 313 ASN B OD1 1 ATOM 6520 N ND2 . ASN B 1 313 ? -56.712 -25.616 266.165 1.00 38.56 ? 313 ASN B ND2 1 ATOM 6521 N N . PRO B 1 314 ? -52.950 -25.660 269.232 1.00 37.65 ? 314 PRO B N 1 ATOM 6522 C CA . PRO B 1 314 ? -51.573 -25.890 268.769 1.00 42.37 ? 314 PRO B CA 1 ATOM 6523 C C . PRO B 1 314 ? -51.484 -26.435 267.353 1.00 36.56 ? 314 PRO B C 1 ATOM 6524 O O . PRO B 1 314 ? -50.376 -26.495 266.804 1.00 36.50 ? 314 PRO B O 1 ATOM 6525 C CB . PRO B 1 314 ? -51.032 -26.901 269.785 1.00 44.80 ? 314 PRO B CB 1 ATOM 6526 C CG . PRO B 1 314 ? -52.244 -27.660 270.214 1.00 50.42 ? 314 PRO B CG 1 ATOM 6527 C CD . PRO B 1 314 ? -53.372 -26.657 270.230 1.00 41.43 ? 314 PRO B CD 1 ATOM 6528 N N . SER B 1 315 ? -52.605 -26.832 266.747 1.00 36.42 ? 315 SER B N 1 ATOM 6529 C CA . SER B 1 315 ? -52.563 -27.347 265.383 1.00 38.68 ? 315 SER B CA 1 ATOM 6530 C C . SER B 1 315 ? -52.331 -26.234 264.369 1.00 37.49 ? 315 SER B C 1 ATOM 6531 O O . SER B 1 315 ? -51.734 -26.474 263.313 1.00 39.33 ? 315 SER B O 1 ATOM 6532 C CB . SER B 1 315 ? -53.858 -28.092 265.063 1.00 41.44 ? 315 SER B CB 1 ATOM 6533 O OG . SER B 1 315 ? -54.113 -29.107 266.018 1.00 63.20 ? 315 SER B OG 1 ATOM 6534 N N . LEU B 1 316 ? -52.788 -25.023 264.668 1.00 38.70 ? 316 LEU B N 1 ATOM 6535 C CA . LEU B 1 316 ? -52.673 -23.901 263.751 1.00 39.27 ? 316 LEU B CA 1 ATOM 6536 C C . LEU B 1 316 ? -51.393 -23.120 264.016 1.00 40.46 ? 316 LEU B C 1 ATOM 6537 O O . LEU B 1 316 ? -50.933 -23.010 265.155 1.00 43.53 ? 316 LEU B O 1 ATOM 6538 C CB . LEU B 1 316 ? -53.880 -22.973 263.885 1.00 39.55 ? 316 LEU B CB 1 ATOM 6539 C CG . LEU B 1 316 ? -55.253 -23.646 263.898 1.00 37.02 ? 316 LEU B CG 1 ATOM 6540 C CD1 . LEU B 1 316 ? -56.338 -22.644 264.259 1.00 58.17 ? 316 LEU B CD1 1 ATOM 6541 C CD2 . LEU B 1 316 ? -55.545 -24.299 262.556 1.00 33.34 ? 316 LEU B CD2 1 ATOM 6542 N N . GLY B 1 317 ? -50.819 -22.574 262.947 1.00 42.48 ? 317 GLY B N 1 ATOM 6543 C CA . GLY B 1 317 ? -49.650 -21.732 263.093 1.00 51.02 ? 317 GLY B CA 1 ATOM 6544 C C . GLY B 1 317 ? -48.628 -21.845 261.983 1.00 71.95 ? 317 GLY B C 1 ATOM 6545 O O . GLY B 1 317 ? -48.163 -22.941 261.654 1.00 90.84 ? 317 GLY B O 1 ATOM 6546 N N . ASP B 1 318 ? -48.276 -20.705 261.394 1.00 63.50 ? 318 ASP B N 1 ATOM 6547 C CA . ASP B 1 318 ? -47.165 -20.623 260.453 1.00 65.13 ? 318 ASP B CA 1 ATOM 6548 C C . ASP B 1 318 ? -46.611 -19.211 260.533 1.00 67.01 ? 318 ASP B C 1 ATOM 6549 O O . ASP B 1 318 ? -47.346 -18.245 260.306 1.00 72.67 ? 318 ASP B O 1 ATOM 6550 C CB . ASP B 1 318 ? -47.604 -20.960 259.028 1.00 66.43 ? 318 ASP B CB 1 ATOM 6551 C CG . ASP B 1 318 ? -46.438 -21.026 258.063 1.00 72.65 ? 318 ASP B CG 1 ATOM 6552 O OD1 . ASP B 1 318 ? -45.278 -21.065 258.525 1.00 81.52 ? 318 ASP B OD1 1 ATOM 6553 O OD2 . ASP B 1 318 ? -46.679 -21.045 256.841 1.00 68.46 ? 318 ASP B OD2 1 ATOM 6554 N N . ALA B 1 319 ? -45.322 -19.097 260.854 1.00 67.93 ? 319 ALA B N 1 ATOM 6555 C CA . ALA B 1 319 ? -44.748 -17.802 261.203 1.00 72.11 ? 319 ALA B CA 1 ATOM 6556 C C . ALA B 1 319 ? -44.772 -16.839 260.021 1.00 72.14 ? 319 ALA B C 1 ATOM 6557 O O . ALA B 1 319 ? -45.399 -15.776 260.081 1.00 69.64 ? 319 ALA B O 1 ATOM 6558 C CB . ALA B 1 319 ? -43.321 -17.989 261.721 1.00 103.63 ? 319 ALA B CB 1 ATOM 6559 N N . GLU B 1 320 ? -44.096 -17.197 258.933 1.00 75.87 ? 320 GLU B N 1 ATOM 6560 C CA . GLU B 1 320 ? -43.813 -16.254 257.860 1.00 80.67 ? 320 GLU B CA 1 ATOM 6561 C C . GLU B 1 320 ? -44.837 -16.285 256.730 1.00 74.05 ? 320 GLU B C 1 ATOM 6562 O O . GLU B 1 320 ? -44.622 -15.630 255.705 1.00 74.47 ? 320 GLU B O 1 ATOM 6563 C CB . GLU B 1 320 ? -42.408 -16.503 257.307 1.00 127.86 ? 320 GLU B CB 1 ATOM 6564 C CG . GLU B 1 320 ? -41.304 -16.174 258.303 1.00 130.68 ? 320 GLU B CG 1 ATOM 6565 C CD . GLU B 1 320 ? -39.917 -16.454 257.761 1.00 140.67 ? 320 GLU B CD 1 ATOM 6566 O OE1 . GLU B 1 320 ? -39.812 -17.084 256.689 1.00 149.25 ? 320 GLU B OE1 1 ATOM 6567 O OE2 . GLU B 1 320 ? -38.932 -16.043 258.410 1.00 137.96 ? 320 GLU B OE2 1 ATOM 6568 N N . ARG B 1 321 ? -45.940 -17.018 256.884 1.00 71.08 ? 321 ARG B N 1 ATOM 6569 C CA . ARG B 1 321 ? -47.058 -16.903 255.954 1.00 69.78 ? 321 ARG B CA 1 ATOM 6570 C C . ARG B 1 321 ? -48.201 -16.082 256.534 1.00 74.10 ? 321 ARG B C 1 ATOM 6571 O O . ARG B 1 321 ? -48.735 -15.197 255.858 1.00 93.22 ? 321 ARG B O 1 ATOM 6572 C CB . ARG B 1 321 ? -47.574 -18.284 255.530 1.00 68.36 ? 321 ARG B CB 1 ATOM 6573 C CG . ARG B 1 321 ? -48.493 -18.219 254.314 1.00 64.30 ? 321 ARG B CG 1 ATOM 6574 C CD . ARG B 1 321 ? -48.492 -19.498 253.487 1.00 61.25 ? 321 ARG B CD 1 ATOM 6575 N NE . ARG B 1 321 ? -48.085 -20.675 254.249 1.00 70.00 ? 321 ARG B NE 1 ATOM 6576 C CZ . ARG B 1 321 ? -47.020 -21.416 253.966 1.00 60.57 ? 321 ARG B CZ 1 ATOM 6577 N NH1 . ARG B 1 321 ? -46.244 -21.103 252.939 1.00 58.32 ? 321 ARG B NH1 1 ATOM 6578 N NH2 . ARG B 1 321 ? -46.727 -22.472 254.714 1.00 73.18 ? 321 ARG B NH2 1 ATOM 6579 N N . ASP B 1 322 ? -48.587 -16.354 257.783 1.00 74.81 ? 322 ASP B N 1 ATOM 6580 C CA . ASP B 1 322 ? -49.561 -15.505 258.456 1.00 67.84 ? 322 ASP B CA 1 ATOM 6581 C C . ASP B 1 322 ? -49.025 -14.100 258.679 1.00 61.65 ? 322 ASP B C 1 ATOM 6582 O O . ASP B 1 322 ? -49.815 -13.166 258.855 1.00 60.23 ? 322 ASP B O 1 ATOM 6583 C CB . ASP B 1 322 ? -49.972 -16.128 259.789 1.00 93.63 ? 322 ASP B CB 1 ATOM 6584 C CG . ASP B 1 322 ? -50.816 -17.373 259.612 1.00 113.66 ? 322 ASP B CG 1 ATOM 6585 O OD1 . ASP B 1 322 ? -51.366 -17.569 258.509 1.00 122.11 ? 322 ASP B OD1 1 ATOM 6586 O OD2 . ASP B 1 322 ? -50.924 -18.158 260.576 1.00 110.95 ? 322 ASP B OD2 1 ATOM 6587 N N . ALA B 1 323 ? -47.700 -13.930 258.676 1.00 62.64 ? 323 ALA B N 1 ATOM 6588 C CA . ALA B 1 323 ? -47.126 -12.593 258.762 1.00 62.81 ? 323 ALA B CA 1 ATOM 6589 C C . ALA B 1 323 ? -47.508 -11.747 257.557 1.00 59.37 ? 323 ALA B C 1 ATOM 6590 O O . ALA B 1 323 ? -47.631 -10.523 257.672 1.00 59.80 ? 323 ALA B O 1 ATOM 6591 C CB . ALA B 1 323 ? -45.605 -12.681 258.893 1.00 90.62 ? 323 ALA B CB 1 ATOM 6592 N N . LYS B 1 324 ? -47.700 -12.377 256.397 1.00 57.93 ? 324 LYS B N 1 ATOM 6593 C CA . LYS B 1 324 ? -48.177 -11.649 255.228 1.00 55.64 ? 324 LYS B CA 1 ATOM 6594 C C . LYS B 1 324 ? -49.679 -11.408 255.305 1.00 63.46 ? 324 LYS B C 1 ATOM 6595 O O . LYS B 1 324 ? -50.163 -10.349 254.892 1.00 81.20 ? 324 LYS B O 1 ATOM 6596 C CB . LYS B 1 324 ? -47.823 -12.414 253.953 1.00 61.62 ? 324 LYS B CB 1 ATOM 6597 C CG . LYS B 1 324 ? -46.344 -12.730 253.809 1.00 82.81 ? 324 LYS B CG 1 ATOM 6598 C CD . LYS B 1 324 ? -45.527 -11.472 253.573 1.00 90.98 ? 324 LYS B CD 1 ATOM 6599 C CE . LYS B 1 324 ? -44.070 -11.807 253.295 1.00 92.04 ? 324 LYS B CE 1 ATOM 6600 N NZ . LYS B 1 324 ? -43.377 -12.332 254.505 1.00 98.23 ? 324 LYS B NZ 1 ATOM 6601 N N . THR B 1 325 ? -50.427 -12.380 255.834 1.00 76.72 ? 325 THR B N 1 ATOM 6602 C CA . THR B 1 325 ? -51.870 -12.214 255.979 1.00 54.08 ? 325 THR B CA 1 ATOM 6603 C C . THR B 1 325 ? -52.197 -11.091 256.954 1.00 45.65 ? 325 THR B C 1 ATOM 6604 O O . THR B 1 325 ? -53.081 -10.267 256.690 1.00 46.07 ? 325 THR B O 1 ATOM 6605 C CB . THR B 1 325 ? -52.503 -13.527 256.445 1.00 53.04 ? 325 THR B CB 1 ATOM 6606 O OG1 . THR B 1 325 ? -52.240 -14.556 255.483 1.00 50.64 ? 325 THR B OG1 1 ATOM 6607 C CG2 . THR B 1 325 ? -54.007 -13.367 256.610 1.00 57.43 ? 325 THR B CG2 1 ATOM 6608 N N . TYR B 1 326 ? -51.488 -11.039 258.084 1.00 45.14 ? 326 TYR B N 1 ATOM 6609 C CA . TYR B 1 326 ? -51.733 -9.998 259.077 1.00 41.74 ? 326 TYR B CA 1 ATOM 6610 C C . TYR B 1 326 ? -51.511 -8.609 258.490 1.00 42.00 ? 326 TYR B C 1 ATOM 6611 O O . TYR B 1 326 ? -52.239 -7.666 258.818 1.00 41.29 ? 326 TYR B O 1 ATOM 6612 C CB . TYR B 1 326 ? -50.832 -10.226 260.292 1.00 42.48 ? 326 TYR B CB 1 ATOM 6613 C CG . TYR B 1 326 ? -51.012 -9.232 261.418 1.00 37.93 ? 326 TYR B CG 1 ATOM 6614 C CD1 . TYR B 1 326 ? -51.961 -9.440 262.410 1.00 39.05 ? 326 TYR B CD1 1 ATOM 6615 C CD2 . TYR B 1 326 ? -50.217 -8.097 261.501 1.00 41.75 ? 326 TYR B CD2 1 ATOM 6616 C CE1 . TYR B 1 326 ? -52.119 -8.539 263.446 1.00 41.74 ? 326 TYR B CE1 1 ATOM 6617 C CE2 . TYR B 1 326 ? -50.365 -7.195 262.533 1.00 40.33 ? 326 TYR B CE2 1 ATOM 6618 C CZ . TYR B 1 326 ? -51.319 -7.418 263.501 1.00 38.44 ? 326 TYR B CZ 1 ATOM 6619 O OH . TYR B 1 326 ? -51.469 -6.516 264.527 1.00 32.55 ? 326 TYR B OH 1 ATOM 6620 N N . ILE B 1 327 ? -50.512 -8.465 257.618 1.00 45.52 ? 327 ILE B N 1 ATOM 6621 C CA . ILE B 1 327 ? -50.271 -7.179 256.972 1.00 45.02 ? 327 ILE B CA 1 ATOM 6622 C C . ILE B 1 327 ? -51.396 -6.856 255.998 1.00 58.16 ? 327 ILE B C 1 ATOM 6623 O O . ILE B 1 327 ? -51.988 -5.771 256.041 1.00 80.61 ? 327 ILE B O 1 ATOM 6624 C CB . ILE B 1 327 ? -48.903 -7.181 256.267 1.00 47.29 ? 327 ILE B CB 1 ATOM 6625 C CG1 . ILE B 1 327 ? -47.772 -7.300 257.290 1.00 55.92 ? 327 ILE B CG1 1 ATOM 6626 C CG2 . ILE B 1 327 ? -48.738 -5.928 255.420 1.00 49.62 ? 327 ILE B CG2 1 ATOM 6627 C CD1 . ILE B 1 327 ? -47.803 -6.236 258.362 1.00 58.87 ? 327 ILE B CD1 1 ATOM 6628 N N . LEU B 1 328 ? -51.712 -7.800 255.109 1.00 46.97 ? 328 LEU B N 1 ATOM 6629 C CA . LEU B 1 328 ? -52.705 -7.544 254.072 1.00 45.11 ? 328 LEU B CA 1 ATOM 6630 C C . LEU B 1 328 ? -54.110 -7.420 254.652 1.00 44.46 ? 328 LEU B C 1 ATOM 6631 O O . LEU B 1 328 ? -54.958 -6.732 254.072 1.00 45.12 ? 328 LEU B O 1 ATOM 6632 C CB . LEU B 1 328 ? -52.633 -8.650 253.019 1.00 47.85 ? 328 LEU B CB 1 ATOM 6633 C CG . LEU B 1 328 ? -53.653 -8.706 251.885 1.00 59.12 ? 328 LEU B CG 1 ATOM 6634 C CD1 . LEU B 1 328 ? -53.539 -7.481 251.000 1.00 76.56 ? 328 LEU B CD1 1 ATOM 6635 C CD2 . LEU B 1 328 ? -53.402 -9.961 251.077 1.00 62.16 ? 328 LEU B CD2 1 ATOM 6636 N N . LEU B 1 329 ? -54.373 -8.060 255.794 1.00 43.56 ? 329 LEU B N 1 ATOM 6637 C CA . LEU B 1 329 ? -55.660 -7.877 256.458 1.00 37.91 ? 329 LEU B CA 1 ATOM 6638 C C . LEU B 1 329 ? -55.812 -6.455 256.982 1.00 35.84 ? 329 LEU B C 1 ATOM 6639 O O . LEU B 1 329 ? -56.875 -5.842 256.832 1.00 40.19 ? 329 LEU B O 1 ATOM 6640 C CB . LEU B 1 329 ? -55.815 -8.883 257.598 1.00 34.39 ? 329 LEU B CB 1 ATOM 6641 C CG . LEU B 1 329 ? -57.155 -8.867 258.337 1.00 31.78 ? 329 LEU B CG 1 ATOM 6642 C CD1 . LEU B 1 329 ? -58.303 -9.154 257.382 1.00 33.71 ? 329 LEU B CD1 1 ATOM 6643 C CD2 . LEU B 1 329 ? -57.151 -9.858 259.490 1.00 30.19 ? 329 LEU B CD2 1 ATOM 6644 N N . LEU B 1 330 ? -54.759 -5.913 257.597 1.00 33.33 ? 330 LEU B N 1 ATOM 6645 C CA . LEU B 1 330 ? -54.833 -4.561 258.139 1.00 32.21 ? 330 LEU B CA 1 ATOM 6646 C C . LEU B 1 330 ? -54.914 -3.522 257.028 1.00 35.97 ? 330 LEU B C 1 ATOM 6647 O O . LEU B 1 330 ? -55.586 -2.496 257.179 1.00 37.28 ? 330 LEU B O 1 ATOM 6648 C CB . LEU B 1 330 ? -53.629 -4.294 259.036 1.00 34.41 ? 330 LEU B CB 1 ATOM 6649 C CG . LEU B 1 330 ? -53.539 -5.141 260.305 1.00 35.16 ? 330 LEU B CG 1 ATOM 6650 C CD1 . LEU B 1 330 ? -52.315 -4.745 261.103 1.00 37.27 ? 330 LEU B CD1 1 ATOM 6651 C CD2 . LEU B 1 330 ? -54.800 -4.995 261.139 1.00 46.09 ? 330 LEU B CD2 1 ATOM 6652 N N . GLU B 1 331 ? -54.230 -3.768 255.907 1.00 42.53 ? 331 GLU B N 1 ATOM 6653 C CA . GLU B 1 331 ? -54.313 -2.850 254.776 1.00 46.61 ? 331 GLU B CA 1 ATOM 6654 C C . GLU B 1 331 ? -55.731 -2.785 254.225 1.00 48.27 ? 331 GLU B C 1 ATOM 6655 O O . GLU B 1 331 ? -56.248 -1.698 253.942 1.00 39.33 ? 331 GLU B O 1 ATOM 6656 C CB . GLU B 1 331 ? -53.337 -3.277 253.680 1.00 44.24 ? 331 GLU B CB 1 ATOM 6657 C CG . GLU B 1 331 ? -51.873 -3.184 254.073 1.00 44.14 ? 331 GLU B CG 1 ATOM 6658 C CD . GLU B 1 331 ? -50.948 -3.660 252.972 1.00 43.93 ? 331 GLU B CD 1 ATOM 6659 O OE1 . GLU B 1 331 ? -51.440 -4.289 252.012 1.00 38.33 ? 331 GLU B OE1 1 ATOM 6660 O OE2 . GLU B 1 331 ? -49.730 -3.403 253.067 1.00 54.78 ? 331 GLU B OE2 1 ATOM 6661 N N . GLU B 1 332 ? -56.377 -3.942 254.073 1.00 39.78 ? 332 GLU B N 1 ATOM 6662 C CA . GLU B 1 332 ? -57.745 -3.967 253.566 1.00 37.77 ? 332 GLU B CA 1 ATOM 6663 C C . GLU B 1 332 ? -58.721 -3.384 254.581 1.00 34.97 ? 332 GLU B C 1 ATOM 6664 O O . GLU B 1 332 ? -59.684 -2.706 254.205 1.00 32.94 ? 332 GLU B O 1 ATOM 6665 C CB . GLU B 1 332 ? -58.137 -5.398 253.199 1.00 39.74 ? 332 GLU B CB 1 ATOM 6666 C CG . GLU B 1 332 ? -57.324 -5.983 252.054 1.00 40.57 ? 332 GLU B CG 1 ATOM 6667 C CD . GLU B 1 332 ? -57.460 -7.489 251.950 1.00 44.37 ? 332 GLU B CD 1 ATOM 6668 O OE1 . GLU B 1 332 ? -58.147 -8.086 252.805 1.00 49.81 ? 332 GLU B OE1 1 ATOM 6669 O OE2 . GLU B 1 332 ? -56.876 -8.077 251.016 1.00 49.84 ? 332 GLU B OE2 1 ATOM 6670 N N . LEU B 1 333 ? -58.489 -3.638 255.872 1.00 34.01 ? 333 LEU B N 1 ATOM 6671 C CA . LEU B 1 333 ? -59.345 -3.059 256.902 1.00 32.21 ? 333 LEU B CA 1 ATOM 6672 C C . LEU B 1 333 ? -59.193 -1.545 256.955 1.00 34.19 ? 333 LEU B C 1 ATOM 6673 O O . LEU B 1 333 ? -60.179 -0.823 257.143 1.00 34.09 ? 333 LEU B O 1 ATOM 6674 C CB . LEU B 1 333 ? -59.025 -3.676 258.264 1.00 30.52 ? 333 LEU B CB 1 ATOM 6675 C CG . LEU B 1 333 ? -59.574 -5.076 258.546 1.00 32.26 ? 333 LEU B CG 1 ATOM 6676 C CD1 . LEU B 1 333 ? -59.169 -5.535 259.938 1.00 28.52 ? 333 LEU B CD1 1 ATOM 6677 C CD2 . LEU B 1 333 ? -61.084 -5.108 258.386 1.00 40.48 ? 333 LEU B CD2 1 ATOM 6678 N N . ARG B 1 334 ? -57.966 -1.046 256.790 1.00 33.94 ? 334 ARG B N 1 ATOM 6679 C CA . ARG B 1 334 ? -57.751 0.397 256.794 1.00 42.18 ? 334 ARG B CA 1 ATOM 6680 C C . ARG B 1 334 ? -58.403 1.055 255.585 1.00 38.79 ? 334 ARG B C 1 ATOM 6681 O O . ARG B 1 334 ? -59.037 2.109 255.711 1.00 37.36 ? 334 ARG B O 1 ATOM 6682 C CB . ARG B 1 334 ? -56.255 0.704 256.831 1.00 38.15 ? 334 ARG B CB 1 ATOM 6683 C CG . ARG B 1 334 ? -55.916 2.187 256.884 1.00 36.91 ? 334 ARG B CG 1 ATOM 6684 C CD . ARG B 1 334 ? -56.360 2.818 258.195 1.00 34.81 ? 334 ARG B CD 1 ATOM 6685 N NE . ARG B 1 334 ? -57.672 3.449 258.088 1.00 35.95 ? 334 ARG B NE 1 ATOM 6686 C CZ . ARG B 1 334 ? -58.299 4.042 259.098 1.00 36.64 ? 334 ARG B CZ 1 ATOM 6687 N NH1 . ARG B 1 334 ? -57.735 4.088 260.297 1.00 35.06 ? 334 ARG B NH1 1 ATOM 6688 N NH2 . ARG B 1 334 ? -59.492 4.591 258.909 1.00 38.03 ? 334 ARG B NH2 1 ATOM 6689 N N . ALA B 1 335 ? -58.261 0.446 254.404 1.00 38.14 ? 335 ALA B N 1 ATOM 6690 C CA . ALA B 1 335 ? -58.887 1.001 253.209 1.00 36.16 ? 335 ALA B CA 1 ATOM 6691 C C . ALA B 1 335 ? -60.405 0.958 253.305 1.00 37.86 ? 335 ALA B C 1 ATOM 6692 O O . ALA B 1 335 ? -61.087 1.848 252.783 1.00 54.76 ? 335 ALA B O 1 ATOM 6693 C CB . ALA B 1 335 ? -58.412 0.248 251.967 1.00 50.68 ? 335 ALA B CB 1 ATOM 6694 N N . MET B 1 336 ? -60.951 -0.063 253.967 1.00 36.54 ? 336 MET B N 1 ATOM 6695 C CA . MET B 1 336 ? -62.398 -0.150 254.131 1.00 40.20 ? 336 MET B CA 1 ATOM 6696 C C . MET B 1 336 ? -62.909 0.913 255.096 1.00 37.81 ? 336 MET B C 1 ATOM 6697 O O . MET B 1 336 ? -63.947 1.537 254.846 1.00 37.99 ? 336 MET B O 1 ATOM 6698 C CB . MET B 1 336 ? -62.779 -1.554 254.605 1.00 47.97 ? 336 MET B CB 1 ATOM 6699 C CG . MET B 1 336 ? -64.218 -1.721 255.067 1.00 31.03 ? 336 MET B CG 1 ATOM 6700 S SD . MET B 1 336 ? -64.463 -1.279 256.798 1.00 20.90 ? 336 MET B SD 1 ATOM 6701 C CE . MET B 1 336 ? -63.138 -2.212 257.548 1.00 37.68 ? 336 MET B CE 1 ATOM 6702 N N . LEU B 1 337 ? -62.199 1.128 256.207 1.00 44.16 ? 337 LEU B N 1 ATOM 6703 C CA . LEU B 1 337 ? -62.614 2.149 257.163 1.00 37.51 ? 337 LEU B CA 1 ATOM 6704 C C . LEU B 1 337 ? -62.548 3.540 256.547 1.00 53.05 ? 337 LEU B C 1 ATOM 6705 O O . LEU B 1 337 ? -63.380 4.402 256.854 1.00 49.40 ? 337 LEU B O 1 ATOM 6706 C CB . LEU B 1 337 ? -61.746 2.084 258.417 1.00 41.05 ? 337 LEU B CB 1 ATOM 6707 C CG . LEU B 1 337 ? -61.904 0.867 259.324 1.00 34.79 ? 337 LEU B CG 1 ATOM 6708 C CD1 . LEU B 1 337 ? -60.962 0.996 260.505 1.00 39.94 ? 337 LEU B CD1 1 ATOM 6709 C CD2 . LEU B 1 337 ? -63.343 0.727 259.792 1.00 34.26 ? 337 LEU B CD2 1 ATOM 6710 N N . ASP B 1 338 ? -61.559 3.781 255.682 1.00 38.59 ? 338 ASP B N 1 ATOM 6711 C CA . ASP B 1 338 ? -61.467 5.071 255.010 1.00 38.13 ? 338 ASP B CA 1 ATOM 6712 C C . ASP B 1 338 ? -62.686 5.331 254.137 1.00 38.70 ? 338 ASP B C 1 ATOM 6713 O O . ASP B 1 338 ? -63.098 6.485 253.975 1.00 41.49 ? 338 ASP B O 1 ATOM 6714 C CB . ASP B 1 338 ? -60.186 5.140 254.180 1.00 39.09 ? 338 ASP B CB 1 ATOM 6715 C CG . ASP B 1 338 ? -58.936 5.070 255.035 1.00 37.97 ? 338 ASP B CG 1 ATOM 6716 O OD1 . ASP B 1 338 ? -59.001 5.463 256.219 1.00 33.59 ? 338 ASP B OD1 1 ATOM 6717 O OD2 . ASP B 1 338 ? -57.890 4.618 254.525 1.00 60.01 ? 338 ASP B OD2 1 ATOM 6718 N N . ASP B 1 339 ? -63.274 4.277 253.568 1.00 37.21 ? 339 ASP B N 1 ATOM 6719 C CA . ASP B 1 339 ? -64.548 4.435 252.877 1.00 36.71 ? 339 ASP B CA 1 ATOM 6720 C C . ASP B 1 339 ? -65.643 4.847 253.850 1.00 39.55 ? 339 ASP B C 1 ATOM 6721 O O . ASP B 1 339 ? -66.465 5.715 253.537 1.00 61.13 ? 339 ASP B O 1 ATOM 6722 C CB . ASP B 1 339 ? -64.926 3.139 252.160 1.00 40.31 ? 339 ASP B CB 1 ATOM 6723 C CG . ASP B 1 339 ? -63.964 2.789 251.044 1.00 41.99 ? 339 ASP B CG 1 ATOM 6724 O OD1 . ASP B 1 339 ? -62.858 3.367 251.008 1.00 50.60 ? 339 ASP B OD1 1 ATOM 6725 O OD2 . ASP B 1 339 ? -64.314 1.934 250.202 1.00 50.26 ? 339 ASP B OD2 1 ATOM 6726 N N . LEU B 1 340 ? -65.662 4.241 255.040 1.00 39.20 ? 340 LEU B N 1 ATOM 6727 C CA . LEU B 1 340 ? -66.652 4.606 256.049 1.00 46.29 ? 340 LEU B CA 1 ATOM 6728 C C . LEU B 1 340 ? -66.471 6.047 256.508 1.00 41.12 ? 340 LEU B C 1 ATOM 6729 O O . LEU B 1 340 ? -67.453 6.747 256.781 1.00 38.40 ? 340 LEU B O 1 ATOM 6730 C CB . LEU B 1 340 ? -66.561 3.654 257.243 1.00 38.90 ? 340 LEU B CB 1 ATOM 6731 C CG . LEU B 1 340 ? -67.391 2.371 257.202 1.00 42.42 ? 340 LEU B CG 1 ATOM 6732 C CD1 . LEU B 1 340 ? -67.050 1.485 258.388 1.00 80.75 ? 340 LEU B CD1 1 ATOM 6733 C CD2 . LEU B 1 340 ? -68.873 2.698 257.193 1.00 43.53 ? 340 LEU B CD2 1 ATOM 6734 N N . GLU B 1 341 ? -65.220 6.507 256.604 1.00 36.50 ? 341 GLU B N 1 ATOM 6735 C CA . GLU B 1 341 ? -64.971 7.875 257.047 1.00 34.50 ? 341 GLU B CA 1 ATOM 6736 C C . GLU B 1 341 ? -65.525 8.886 256.052 1.00 36.00 ? 341 GLU B C 1 ATOM 6737 O O . GLU B 1 341 ? -66.136 9.885 256.447 1.00 35.67 ? 341 GLU B O 1 ATOM 6738 C CB . GLU B 1 341 ? -63.474 8.092 257.266 1.00 34.32 ? 341 GLU B CB 1 ATOM 6739 C CG . GLU B 1 341 ? -62.907 7.312 258.441 1.00 34.65 ? 341 GLU B CG 1 ATOM 6740 C CD . GLU B 1 341 ? -61.441 7.606 258.683 1.00 31.51 ? 341 GLU B CD 1 ATOM 6741 O OE1 . GLU B 1 341 ? -60.830 8.315 257.856 1.00 36.82 ? 341 GLU B OE1 1 ATOM 6742 O OE2 . GLU B 1 341 ? -60.900 7.131 259.703 1.00 31.83 ? 341 GLU B OE2 1 ATOM 6743 N N . ALA B 1 342 ? -65.324 8.644 254.755 1.00 51.15 ? 342 ALA B N 1 ATOM 6744 C CA . ALA B 1 342 ? -65.944 9.490 253.744 1.00 38.82 ? 342 ALA B CA 1 ATOM 6745 C C . ALA B 1 342 ? -67.432 9.207 253.596 1.00 39.40 ? 342 ALA B C 1 ATOM 6746 O O . ALA B 1 342 ? -68.168 10.064 253.097 1.00 42.45 ? 342 ALA B O 1 ATOM 6747 C CB . ALA B 1 342 ? -65.242 9.308 252.398 1.00 52.58 ? 342 ALA B CB 1 ATOM 6748 N N . GLN B 1 343 ? -67.887 8.027 254.021 1.00 42.57 ? 343 GLN B N 1 ATOM 6749 C CA . GLN B 1 343 ? -69.302 7.687 253.938 1.00 43.42 ? 343 GLN B CA 1 ATOM 6750 C C . GLN B 1 343 ? -70.105 8.357 255.045 1.00 42.55 ? 343 GLN B C 1 ATOM 6751 O O . GLN B 1 343 ? -71.222 8.831 254.807 1.00 73.61 ? 343 GLN B O 1 ATOM 6752 C CB . GLN B 1 343 ? -69.476 6.169 254.005 1.00 49.52 ? 343 GLN B CB 1 ATOM 6753 C CG . GLN B 1 343 ? -70.650 5.621 253.217 1.00 55.35 ? 343 GLN B CG 1 ATOM 6754 C CD . GLN B 1 343 ? -70.920 4.163 253.536 1.00 77.60 ? 343 GLN B CD 1 ATOM 6755 O OE1 . GLN B 1 343 ? -70.287 3.583 254.417 1.00 73.64 ? 343 GLN B OE1 1 ATOM 6756 N NE2 . GLN B 1 343 ? -71.864 3.564 252.820 1.00 99.83 ? 343 GLN B NE2 1 ATOM 6757 N N . THR B 1 344 ? -69.553 8.410 256.258 1.00 35.67 ? 344 THR B N 1 ATOM 6758 C CA . THR B 1 344 ? -70.267 8.928 257.415 1.00 33.31 ? 344 THR B CA 1 ATOM 6759 C C . THR B 1 344 ? -69.712 10.243 257.942 1.00 31.69 ? 344 THR B C 1 ATOM 6760 O O . THR B 1 344 ? -70.313 10.825 258.851 1.00 34.32 ? 344 THR B O 1 ATOM 6761 C CB . THR B 1 344 ? -70.252 7.895 258.551 1.00 34.24 ? 344 THR B CB 1 ATOM 6762 O OG1 . THR B 1 344 ? -68.906 7.700 259.002 1.00 33.19 ? 344 THR B OG1 1 ATOM 6763 C CG2 . THR B 1 344 ? -70.815 6.566 258.070 1.00 39.65 ? 344 THR B CG2 1 ATOM 6764 N N . GLY B 1 345 ? -68.594 10.726 257.405 1.00 31.80 ? 345 GLY B N 1 ATOM 6765 C CA . GLY B 1 345 ? -67.971 11.912 257.955 1.00 29.53 ? 345 GLY B CA 1 ATOM 6766 C C . GLY B 1 345 ? -67.350 11.723 259.319 1.00 26.89 ? 345 GLY B C 1 ATOM 6767 O O . GLY B 1 345 ? -66.984 12.712 259.961 1.00 28.88 ? 345 GLY B O 1 ATOM 6768 N N . ARG B 1 346 ? -67.215 10.483 259.780 1.00 26.46 ? 346 ARG B N 1 ATOM 6769 C CA . ARG B 1 346 ? -66.695 10.175 261.100 1.00 26.61 ? 346 ARG B CA 1 ATOM 6770 C C . ARG B 1 346 ? -65.216 9.808 261.013 1.00 29.28 ? 346 ARG B C 1 ATOM 6771 O O . ARG B 1 346 ? -64.608 9.793 259.939 1.00 29.02 ? 346 ARG B O 1 ATOM 6772 C CB . ARG B 1 346 ? -67.503 9.041 261.733 1.00 26.64 ? 346 ARG B CB 1 ATOM 6773 C CG . ARG B 1 346 ? -68.983 9.339 261.887 1.00 34.86 ? 346 ARG B CG 1 ATOM 6774 C CD . ARG B 1 346 ? -69.754 8.087 262.271 1.00 29.14 ? 346 ARG B CD 1 ATOM 6775 N NE . ARG B 1 346 ? -69.212 7.450 263.467 1.00 21.97 ? 346 ARG B NE 1 ATOM 6776 C CZ . ARG B 1 346 ? -69.712 6.349 264.017 1.00 21.54 ? 346 ARG B CZ 1 ATOM 6777 N NH1 . ARG B 1 346 ? -70.771 5.759 263.479 1.00 21.45 ? 346 ARG B NH1 1 ATOM 6778 N NH2 . ARG B 1 346 ? -69.155 5.836 265.105 1.00 26.27 ? 346 ARG B NH2 1 ATOM 6779 N N . VAL B 1 347 ? -64.633 9.503 262.168 1.00 27.61 ? 347 VAL B N 1 ATOM 6780 C CA . VAL B 1 347 ? -63.246 9.066 262.272 1.00 28.69 ? 347 VAL B CA 1 ATOM 6781 C C . VAL B 1 347 ? -63.248 7.644 262.812 1.00 31.46 ? 347 VAL B C 1 ATOM 6782 O O . VAL B 1 347 ? -63.737 7.397 263.922 1.00 40.95 ? 347 VAL B O 1 ATOM 6783 C CB . VAL B 1 347 ? -62.418 9.994 263.175 1.00 34.31 ? 347 VAL B CB 1 ATOM 6784 C CG1 . VAL B 1 347 ? -61.002 9.462 263.324 1.00 36.92 ? 347 VAL B CG1 1 ATOM 6785 C CG2 . VAL B 1 347 ? -62.408 11.408 262.615 1.00 59.46 ? 347 VAL B CG2 1 ATOM 6786 N N . TYR B 1 348 ? -62.710 6.712 262.031 1.00 30.18 ? 348 TYR B N 1 ATOM 6787 C CA . TYR B 1 348 ? -62.641 5.308 262.411 1.00 29.55 ? 348 TYR B CA 1 ATOM 6788 C C . TYR B 1 348 ? -61.191 4.911 262.644 1.00 32.32 ? 348 TYR B C 1 ATOM 6789 O O . TYR B 1 348 ? -60.318 5.217 261.825 1.00 35.07 ? 348 TYR B O 1 ATOM 6790 C CB . TYR B 1 348 ? -63.269 4.415 261.338 1.00 32.18 ? 348 TYR B CB 1 ATOM 6791 C CG . TYR B 1 348 ? -64.780 4.397 261.368 1.00 34.51 ? 348 TYR B CG 1 ATOM 6792 C CD1 . TYR B 1 348 ? -65.466 3.595 262.270 1.00 33.60 ? 348 TYR B CD1 1 ATOM 6793 C CD2 . TYR B 1 348 ? -65.522 5.178 260.491 1.00 53.67 ? 348 TYR B CD2 1 ATOM 6794 C CE1 . TYR B 1 348 ? -66.847 3.574 262.303 1.00 32.19 ? 348 TYR B CE1 1 ATOM 6795 C CE2 . TYR B 1 348 ? -66.905 5.163 260.516 1.00 44.56 ? 348 TYR B CE2 1 ATOM 6796 C CZ . TYR B 1 348 ? -67.561 4.359 261.423 1.00 32.63 ? 348 TYR B CZ 1 ATOM 6797 O OH . TYR B 1 348 ? -68.937 4.339 261.452 1.00 31.40 ? 348 TYR B OH 1 ATOM 6798 N N . GLU B 1 349 ? -60.942 4.233 263.758 1.00 31.73 ? 349 GLU B N 1 ATOM 6799 C CA . GLU B 1 349 ? -59.614 3.771 264.128 1.00 31.92 ? 349 GLU B CA 1 ATOM 6800 C C . GLU B 1 349 ? -59.449 2.295 263.786 1.00 27.96 ? 349 GLU B C 1 ATOM 6801 O O . GLU B 1 349 ? -60.419 1.546 263.658 1.00 25.23 ? 349 GLU B O 1 ATOM 6802 C CB . GLU B 1 349 ? -59.363 3.994 265.622 1.00 30.24 ? 349 GLU B CB 1 ATOM 6803 C CG . GLU B 1 349 ? -59.408 5.451 266.050 1.00 30.25 ? 349 GLU B CG 1 ATOM 6804 C CD . GLU B 1 349 ? -59.320 5.619 267.553 1.00 24.04 ? 349 GLU B CD 1 ATOM 6805 O OE1 . GLU B 1 349 ? -58.806 4.702 268.227 1.00 26.14 ? 349 GLU B OE1 1 ATOM 6806 O OE2 . GLU B 1 349 ? -59.764 6.669 268.063 1.00 29.68 ? 349 GLU B OE2 1 ATOM 6807 N N . LEU B 1 350 ? -58.193 1.883 263.634 1.00 31.23 ? 350 LEU B N 1 ATOM 6808 C CA . LEU B 1 350 ? -57.844 0.488 263.376 1.00 29.83 ? 350 LEU B CA 1 ATOM 6809 C C . LEU B 1 350 ? -56.684 0.133 264.299 1.00 24.77 ? 350 LEU B C 1 ATOM 6810 O O . LEU B 1 350 ? -55.540 0.519 264.045 1.00 24.24 ? 350 LEU B O 1 ATOM 6811 C CB . LEU B 1 350 ? -57.483 0.263 261.911 1.00 28.37 ? 350 LEU B CB 1 ATOM 6812 C CG . LEU B 1 350 ? -57.040 -1.154 261.538 1.00 26.68 ? 350 LEU B CG 1 ATOM 6813 C CD1 . LEU B 1 350 ? -58.092 -2.175 261.940 1.00 23.82 ? 350 LEU B CD1 1 ATOM 6814 C CD2 . LEU B 1 350 ? -56.744 -1.245 260.051 1.00 38.34 ? 350 LEU B CD2 1 ATOM 6815 N N . THR B 1 351 ? -56.980 -0.592 265.371 1.00 23.50 ? 351 THR B N 1 ATOM 6816 C CA . THR B 1 351 ? -55.986 -0.971 266.360 1.00 24.60 ? 351 THR B CA 1 ATOM 6817 C C . THR B 1 351 ? -55.858 -2.487 266.411 1.00 22.46 ? 351 THR B C 1 ATOM 6818 O O . THR B 1 351 ? -56.664 -3.226 265.841 1.00 19.43 ? 351 THR B O 1 ATOM 6819 C CB . THR B 1 351 ? -56.348 -0.427 267.746 1.00 23.66 ? 351 THR B CB 1 ATOM 6820 O OG1 . THR B 1 351 ? -57.517 -1.099 268.232 1.00 20.36 ? 351 THR B OG1 1 ATOM 6821 C CG2 . THR B 1 351 ? -56.620 1.066 267.677 1.00 27.55 ? 351 THR B CG2 1 ATOM 6822 N N . SER B 1 352 ? -54.824 -2.944 267.113 1.00 26.28 ? 352 SER B N 1 ATOM 6823 C CA . SER B 1 352 ? -54.564 -4.367 267.258 1.00 24.59 ? 352 SER B CA 1 ATOM 6824 C C . SER B 1 352 ? -53.774 -4.604 268.534 1.00 24.03 ? 352 SER B C 1 ATOM 6825 O O . SER B 1 352 ? -52.881 -3.824 268.874 1.00 23.77 ? 352 SER B O 1 ATOM 6826 C CB . SER B 1 352 ? -53.796 -4.925 266.057 1.00 27.37 ? 352 SER B CB 1 ATOM 6827 O OG . SER B 1 352 ? -53.407 -6.268 266.286 1.00 35.72 ? 352 SER B OG 1 ATOM 6828 N N . ALA B 1 353 ? -54.109 -5.684 269.232 1.00 24.09 ? 353 ALA B N 1 ATOM 6829 C CA . ALA B 1 353 ? -53.416 -6.077 270.450 1.00 22.14 ? 353 ALA B CA 1 ATOM 6830 C C . ALA B 1 353 ? -52.457 -7.216 270.138 1.00 22.40 ? 353 ALA B C 1 ATOM 6831 O O . ALA B 1 353 ? -52.865 -8.246 269.592 1.00 22.22 ? 353 ALA B O 1 ATOM 6832 C CB . ALA B 1 353 ? -54.406 -6.496 271.537 1.00 21.32 ? 353 ALA B CB 1 ATOM 6833 N N . ILE B 1 354 ? -51.185 -7.024 270.479 1.00 23.29 ? 354 ILE B N 1 ATOM 6834 C CA . ILE B 1 354 ? -50.148 -8.008 270.210 1.00 24.76 ? 354 ILE B CA 1 ATOM 6835 C C . ILE B 1 354 ? -49.535 -8.441 271.534 1.00 24.15 ? 354 ILE B C 1 ATOM 6836 O O . ILE B 1 354 ? -49.637 -7.753 272.551 1.00 27.00 ? 354 ILE B O 1 ATOM 6837 C CB . ILE B 1 354 ? -49.063 -7.463 269.263 1.00 31.21 ? 354 ILE B CB 1 ATOM 6838 C CG1 . ILE B 1 354 ? -48.238 -6.387 269.971 1.00 29.36 ? 354 ILE B CG1 1 ATOM 6839 C CG2 . ILE B 1 354 ? -49.702 -6.892 268.010 1.00 31.38 ? 354 ILE B CG2 1 ATOM 6840 C CD1 . ILE B 1 354 ? -47.015 -5.952 269.201 1.00 31.67 ? 354 ILE B CD1 1 ATOM 6841 N N . SER B 1 355 ? -48.888 -9.601 271.507 1.00 31.78 ? 355 SER B N 1 ATOM 6842 C CA . SER B 1 355 ? -48.254 -10.124 272.703 1.00 30.95 ? 355 SER B CA 1 ATOM 6843 C C . SER B 1 355 ? -46.907 -9.451 272.940 1.00 35.01 ? 355 SER B C 1 ATOM 6844 O O . SER B 1 355 ? -46.280 -8.908 272.026 1.00 33.17 ? 355 SER B O 1 ATOM 6845 C CB . SER B 1 355 ? -48.065 -11.635 272.599 1.00 27.27 ? 355 SER B CB 1 ATOM 6846 O OG . SER B 1 355 ? -47.554 -12.166 273.809 1.00 27.96 ? 355 SER B OG 1 ATOM 6847 N N . ALA B 1 356 ? -46.463 -9.500 274.194 1.00 35.88 ? 356 ALA B N 1 ATOM 6848 C CA . ALA B 1 356 ? -45.189 -8.928 274.599 1.00 28.63 ? 356 ALA B CA 1 ATOM 6849 C C . ALA B 1 356 ? -44.049 -9.938 274.541 1.00 30.31 ? 356 ALA B C 1 ATOM 6850 O O . ALA B 1 356 ? -43.030 -9.748 275.216 1.00 30.96 ? 356 ALA B O 1 ATOM 6851 C CB . ALA B 1 356 ? -45.303 -8.341 276.006 1.00 27.28 ? 356 ALA B CB 1 ATOM 6852 N N . GLY B 1 357 ? -44.196 -11.002 273.755 1.00 34.68 ? 357 GLY B N 1 ATOM 6853 C CA . GLY B 1 357 ? -43.171 -12.010 273.621 1.00 38.03 ? 357 GLY B CA 1 ATOM 6854 C C . GLY B 1 357 ? -42.298 -11.745 272.413 1.00 31.76 ? 357 GLY B C 1 ATOM 6855 O O . GLY B 1 357 ? -42.791 -11.653 271.287 1.00 29.97 ? 357 GLY B O 1 ATOM 6856 N N . TYR B 1 358 ? -40.990 -11.624 272.654 1.00 34.84 ? 358 TYR B N 1 ATOM 6857 C CA . TYR B 1 358 ? -40.056 -11.343 271.568 1.00 32.69 ? 358 TYR B CA 1 ATOM 6858 C C . TYR B 1 358 ? -40.108 -12.426 270.500 1.00 33.99 ? 358 TYR B C 1 ATOM 6859 O O . TYR B 1 358 ? -39.961 -12.139 269.307 1.00 34.56 ? 358 TYR B O 1 ATOM 6860 C CB . TYR B 1 358 ? -38.638 -11.202 272.122 1.00 28.85 ? 358 TYR B CB 1 ATOM 6861 C CG . TYR B 1 358 ? -38.037 -12.506 272.594 1.00 30.76 ? 358 TYR B CG 1 ATOM 6862 C CD1 . TYR B 1 358 ? -38.298 -12.991 273.867 1.00 33.38 ? 358 TYR B CD1 1 ATOM 6863 C CD2 . TYR B 1 358 ? -37.204 -13.248 271.767 1.00 31.83 ? 358 TYR B CD2 1 ATOM 6864 C CE1 . TYR B 1 358 ? -37.753 -14.183 274.301 1.00 35.44 ? 358 TYR B CE1 1 ATOM 6865 C CE2 . TYR B 1 358 ? -36.654 -14.439 272.192 1.00 34.01 ? 358 TYR B CE2 1 ATOM 6866 C CZ . TYR B 1 358 ? -36.931 -14.901 273.460 1.00 34.59 ? 358 TYR B CZ 1 ATOM 6867 O OH . TYR B 1 358 ? -36.384 -16.087 273.887 1.00 51.65 ? 358 TYR B OH 1 ATOM 6868 N N . ASP B 1 359 ? -40.316 -13.680 270.909 1.00 32.59 ? 359 ASP B N 1 ATOM 6869 C CA . ASP B 1 359 ? -40.473 -14.762 269.946 1.00 30.80 ? 359 ASP B CA 1 ATOM 6870 C C . ASP B 1 359 ? -41.729 -14.597 269.103 1.00 34.34 ? 359 ASP B C 1 ATOM 6871 O O . ASP B 1 359 ? -41.817 -15.189 268.022 1.00 36.41 ? 359 ASP B O 1 ATOM 6872 C CB . ASP B 1 359 ? -40.502 -16.109 270.669 1.00 30.94 ? 359 ASP B CB 1 ATOM 6873 C CG . ASP B 1 359 ? -41.584 -16.177 271.729 1.00 34.27 ? 359 ASP B CG 1 ATOM 6874 O OD1 . ASP B 1 359 ? -41.847 -15.142 272.377 1.00 35.00 ? 359 ASP B OD1 1 ATOM 6875 O OD2 . ASP B 1 359 ? -42.169 -17.264 271.916 1.00 46.73 ? 359 ASP B OD2 1 ATOM 6876 N N . LYS B 1 360 ? -42.695 -13.811 269.573 1.00 35.63 ? 360 LYS B N 1 ATOM 6877 C CA . LYS B 1 360 ? -43.912 -13.506 268.833 1.00 34.24 ? 360 LYS B CA 1 ATOM 6878 C C . LYS B 1 360 ? -43.843 -12.160 268.129 1.00 34.01 ? 360 LYS B C 1 ATOM 6879 O O . LYS B 1 360 ? -44.358 -12.020 267.015 1.00 36.69 ? 360 LYS B O 1 ATOM 6880 C CB . LYS B 1 360 ? -45.116 -13.524 269.778 1.00 33.29 ? 360 LYS B CB 1 ATOM 6881 C CG . LYS B 1 360 ? -45.096 -14.672 270.772 1.00 36.37 ? 360 LYS B CG 1 ATOM 6882 C CD . LYS B 1 360 ? -46.001 -14.376 271.950 1.00 52.72 ? 360 LYS B CD 1 ATOM 6883 C CE . LYS B 1 360 ? -45.935 -15.467 272.999 1.00 42.59 ? 360 LYS B CE 1 ATOM 6884 N NZ . LYS B 1 360 ? -44.531 -15.820 273.343 1.00 40.17 ? 360 LYS B NZ 1 ATOM 6885 N N . ILE B 1 361 ? -43.217 -11.163 268.760 1.00 34.09 ? 361 ILE B N 1 ATOM 6886 C CA . ILE B 1 361 ? -43.029 -9.866 268.116 1.00 35.75 ? 361 ILE B CA 1 ATOM 6887 C C . ILE B 1 361 ? -42.110 -9.996 266.909 1.00 44.78 ? 361 ILE B C 1 ATOM 6888 O O . ILE B 1 361 ? -42.238 -9.244 265.935 1.00 47.76 ? 361 ILE B O 1 ATOM 6889 C CB . ILE B 1 361 ? -42.489 -8.842 269.136 1.00 33.47 ? 361 ILE B CB 1 ATOM 6890 C CG1 . ILE B 1 361 ? -43.435 -8.726 270.332 1.00 39.38 ? 361 ILE B CG1 1 ATOM 6891 C CG2 . ILE B 1 361 ? -42.293 -7.481 268.489 1.00 39.28 ? 361 ILE B CG2 1 ATOM 6892 C CD1 . ILE B 1 361 ? -42.980 -7.729 271.376 1.00 35.18 ? 361 ILE B CD1 1 ATOM 6893 N N . ALA B 1 362 ? -41.181 -10.953 266.941 1.00 50.09 ? 362 ALA B N 1 ATOM 6894 C CA . ALA B 1 362 ? -40.273 -11.153 265.820 1.00 41.60 ? 362 ALA B CA 1 ATOM 6895 C C . ALA B 1 362 ? -40.934 -11.849 264.638 1.00 46.30 ? 362 ALA B C 1 ATOM 6896 O O . ALA B 1 362 ? -40.417 -11.761 263.520 1.00 51.03 ? 362 ALA B O 1 ATOM 6897 C CB . ALA B 1 362 ? -39.049 -11.956 266.265 1.00 40.37 ? 362 ALA B CB 1 ATOM 6898 N N . VAL B 1 363 ? -42.054 -12.538 264.856 1.00 45.46 ? 363 VAL B N 1 ATOM 6899 C CA . VAL B 1 363 ? -42.757 -13.224 263.776 1.00 47.44 ? 363 VAL B CA 1 ATOM 6900 C C . VAL B 1 363 ? -43.301 -12.183 262.809 1.00 49.23 ? 363 VAL B C 1 ATOM 6901 O O . VAL B 1 363 ? -42.756 -11.988 261.716 1.00 50.16 ? 363 VAL B O 1 ATOM 6902 C CB . VAL B 1 363 ? -43.883 -14.124 264.317 1.00 48.36 ? 363 VAL B CB 1 ATOM 6903 C CG1 . VAL B 1 363 ? -44.687 -14.714 263.169 1.00 59.46 ? 363 VAL B CG1 1 ATOM 6904 C CG2 . VAL B 1 363 ? -43.306 -15.227 265.186 1.00 47.87 ? 363 VAL B CG2 1 ATOM 6905 N N . VAL B 1 364 ? -44.375 -11.509 263.202 1.00 53.89 ? 364 VAL B N 1 ATOM 6906 C CA . VAL B 1 364 ? -44.907 -10.389 262.437 1.00 66.19 ? 364 VAL B CA 1 ATOM 6907 C C . VAL B 1 364 ? -44.266 -9.115 262.959 1.00 62.39 ? 364 VAL B C 1 ATOM 6908 O O . VAL B 1 364 ? -44.332 -8.822 264.157 1.00 72.88 ? 364 VAL B O 1 ATOM 6909 C CB . VAL B 1 364 ? -46.437 -10.318 262.546 1.00 65.48 ? 364 VAL B CB 1 ATOM 6910 C CG1 . VAL B 1 364 ? -46.968 -9.204 261.661 1.00 61.89 ? 364 VAL B CG1 1 ATOM 6911 C CG2 . VAL B 1 364 ? -47.048 -11.647 262.171 1.00 86.85 ? 364 VAL B CG2 1 ATOM 6912 N N . ASN B 1 365 ? -43.645 -8.359 262.064 1.00 53.83 ? 365 ASN B N 1 ATOM 6913 C CA . ASN B 1 365 ? -42.881 -7.179 262.435 1.00 57.29 ? 365 ASN B CA 1 ATOM 6914 C C . ASN B 1 365 ? -43.590 -5.940 261.901 1.00 52.61 ? 365 ASN B C 1 ATOM 6915 O O . ASN B 1 365 ? -43.944 -5.883 260.718 1.00 48.89 ? 365 ASN B O 1 ATOM 6916 C CB . ASN B 1 365 ? -41.452 -7.292 261.910 1.00 68.95 ? 365 ASN B CB 1 ATOM 6917 C CG . ASN B 1 365 ? -40.484 -7.782 262.970 1.00 81.50 ? 365 ASN B CG 1 ATOM 6918 O OD1 . ASN B 1 365 ? -39.776 -6.992 263.594 1.00 64.67 ? 365 ASN B OD1 1 ATOM 6919 N ND2 . ASN B 1 365 ? -40.455 -9.091 263.184 1.00 87.06 ? 365 ASN B ND2 1 ATOM 6920 N N . TYR B 1 366 ? -43.780 -4.950 262.773 1.00 50.07 ? 366 TYR B N 1 ATOM 6921 C CA . TYR B 1 366 ? -44.847 -3.969 262.627 1.00 44.51 ? 366 TYR B CA 1 ATOM 6922 C C . TYR B 1 366 ? -44.397 -2.642 262.029 1.00 45.17 ? 366 TYR B C 1 ATOM 6923 O O . TYR B 1 366 ? -45.147 -1.663 262.104 1.00 53.94 ? 366 TYR B O 1 ATOM 6924 C CB . TYR B 1 366 ? -45.509 -3.721 263.984 1.00 45.67 ? 366 TYR B CB 1 ATOM 6925 C CG . TYR B 1 366 ? -46.011 -4.982 264.649 1.00 49.65 ? 366 TYR B CG 1 ATOM 6926 C CD1 . TYR B 1 366 ? -47.314 -5.421 264.462 1.00 56.96 ? 366 TYR B CD1 1 ATOM 6927 C CD2 . TYR B 1 366 ? -45.179 -5.732 265.469 1.00 50.57 ? 366 TYR B CD2 1 ATOM 6928 C CE1 . TYR B 1 366 ? -47.771 -6.575 265.069 1.00 54.14 ? 366 TYR B CE1 1 ATOM 6929 C CE2 . TYR B 1 366 ? -45.627 -6.882 266.082 1.00 48.86 ? 366 TYR B CE2 1 ATOM 6930 C CZ . TYR B 1 366 ? -46.923 -7.301 265.878 1.00 46.45 ? 366 TYR B CZ 1 ATOM 6931 O OH . TYR B 1 366 ? -47.367 -8.451 266.489 1.00 61.73 ? 366 TYR B OH 1 ATOM 6932 N N . ALA B 1 367 ? -43.200 -2.571 261.441 1.00 48.32 ? 367 ALA B N 1 ATOM 6933 C CA . ALA B 1 367 ? -42.842 -1.359 260.711 1.00 43.24 ? 367 ALA B CA 1 ATOM 6934 C C . ALA B 1 367 ? -43.748 -1.165 259.505 1.00 40.18 ? 367 ALA B C 1 ATOM 6935 O O . ALA B 1 367 ? -44.026 -0.026 259.111 1.00 39.44 ? 367 ALA B O 1 ATOM 6936 C CB . ALA B 1 367 ? -41.379 -1.399 260.272 1.00 49.82 ? 367 ALA B CB 1 ATOM 6937 N N . GLU B 1 368 ? -44.218 -2.262 258.913 1.00 47.02 ? 368 GLU B N 1 ATOM 6938 C CA . GLU B 1 368 ? -45.216 -2.203 257.856 1.00 42.74 ? 368 GLU B CA 1 ATOM 6939 C C . GLU B 1 368 ? -46.634 -2.157 258.403 1.00 60.07 ? 368 GLU B C 1 ATOM 6940 O O . GLU B 1 368 ? -47.503 -1.514 257.801 1.00 56.08 ? 368 GLU B O 1 ATOM 6941 C CB . GLU B 1 368 ? -45.068 -3.411 256.926 1.00 41.30 ? 368 GLU B CB 1 ATOM 6942 C CG . GLU B 1 368 ? -44.024 -3.238 255.840 1.00 39.95 ? 368 GLU B CG 1 ATOM 6943 C CD . GLU B 1 368 ? -44.431 -2.213 254.802 1.00 35.09 ? 368 GLU B CD 1 ATOM 6944 O OE1 . GLU B 1 368 ? -45.648 -2.035 254.584 1.00 35.93 ? 368 GLU B OE1 1 ATOM 6945 O OE2 . GLU B 1 368 ? -43.535 -1.582 254.206 1.00 40.30 ? 368 GLU B OE2 1 ATOM 6946 N N . ALA B 1 369 ? -46.884 -2.820 259.535 1.00 53.08 ? 369 ALA B N 1 ATOM 6947 C CA . ALA B 1 369 ? -48.226 -2.836 260.106 1.00 54.15 ? 369 ALA B CA 1 ATOM 6948 C C . ALA B 1 369 ? -48.632 -1.469 260.638 1.00 39.13 ? 369 ALA B C 1 ATOM 6949 O O . ALA B 1 369 ? -49.828 -1.163 260.702 1.00 41.71 ? 369 ALA B O 1 ATOM 6950 C CB . ALA B 1 369 ? -48.314 -3.883 261.217 1.00 67.66 ? 369 ALA B CB 1 ATOM 6951 N N . GLN B 1 370 ? -47.663 -0.637 261.024 1.00 37.63 ? 370 GLN B N 1 ATOM 6952 C CA . GLN B 1 370 ? -47.984 0.691 261.531 1.00 35.80 ? 370 GLN B CA 1 ATOM 6953 C C . GLN B 1 370 ? -48.473 1.634 260.440 1.00 33.53 ? 370 GLN B C 1 ATOM 6954 O O . GLN B 1 370 ? -49.002 2.703 260.763 1.00 33.26 ? 370 GLN B O 1 ATOM 6955 C CB . GLN B 1 370 ? -46.769 1.299 262.234 1.00 40.57 ? 370 GLN B CB 1 ATOM 6956 C CG . GLN B 1 370 ? -45.690 1.805 261.293 1.00 45.69 ? 370 GLN B CG 1 ATOM 6957 C CD . GLN B 1 370 ? -44.570 2.518 262.025 1.00 42.75 ? 370 GLN B CD 1 ATOM 6958 O OE1 . GLN B 1 370 ? -44.655 2.760 263.229 1.00 43.72 ? 370 GLN B OE1 1 ATOM 6959 N NE2 . GLN B 1 370 ? -43.513 2.862 261.299 1.00 45.71 ? 370 GLN B NE2 1 ATOM 6960 N N . LYS B 1 371 ? -48.314 1.270 259.167 1.00 33.08 ? 371 LYS B N 1 ATOM 6961 C CA . LYS B 1 371 ? -48.842 2.079 258.075 1.00 33.72 ? 371 LYS B CA 1 ATOM 6962 C C . LYS B 1 371 ? -50.357 1.996 257.960 1.00 34.15 ? 371 LYS B C 1 ATOM 6963 O O . LYS B 1 371 ? -50.939 2.704 257.131 1.00 40.65 ? 371 LYS B O 1 ATOM 6964 C CB . LYS B 1 371 ? -48.191 1.664 256.754 1.00 35.87 ? 371 LYS B CB 1 ATOM 6965 C CG . LYS B 1 371 ? -46.684 1.857 256.732 1.00 47.59 ? 371 LYS B CG 1 ATOM 6966 C CD . LYS B 1 371 ? -46.129 1.750 255.324 1.00 35.87 ? 371 LYS B CD 1 ATOM 6967 C CE . LYS B 1 371 ? -44.622 1.941 255.315 1.00 38.28 ? 371 LYS B CE 1 ATOM 6968 N NZ . LYS B 1 371 ? -43.900 0.730 255.787 1.00 50.14 ? 371 LYS B NZ 1 ATOM 6969 N N . SER B 1 372 ? -51.004 1.152 258.762 1.00 32.66 ? 372 SER B N 1 ATOM 6970 C CA . SER B 1 372 ? -52.457 1.081 258.818 1.00 30.36 ? 372 SER B CA 1 ATOM 6971 C C . SER B 1 372 ? -53.018 1.107 260.231 1.00 36.67 ? 372 SER B C 1 ATOM 6972 O O . SER B 1 372 ? -54.188 1.471 260.399 1.00 67.28 ? 372 SER B O 1 ATOM 6973 C CB . SER B 1 372 ? -52.962 -0.186 258.113 1.00 32.74 ? 372 SER B CB 1 ATOM 6974 O OG . SER B 1 372 ? -52.458 -1.348 258.743 1.00 35.19 ? 372 SER B OG 1 ATOM 6975 N N . LEU B 1 373 ? -52.236 0.741 261.244 1.00 33.04 ? 373 LEU B N 1 ATOM 6976 C CA . LEU B 1 373 ? -52.710 0.764 262.619 1.00 30.41 ? 373 LEU B CA 1 ATOM 6977 C C . LEU B 1 373 ? -52.553 2.153 263.220 1.00 27.82 ? 373 LEU B C 1 ATOM 6978 O O . LEU B 1 373 ? -51.590 2.868 262.929 1.00 29.26 ? 373 LEU B O 1 ATOM 6979 C CB . LEU B 1 373 ? -51.949 -0.255 263.466 1.00 29.74 ? 373 LEU B CB 1 ATOM 6980 C CG . LEU B 1 373 ? -52.159 -1.725 263.109 1.00 33.94 ? 373 LEU B CG 1 ATOM 6981 C CD1 . LEU B 1 373 ? -51.360 -2.623 264.039 1.00 28.89 ? 373 LEU B CD1 1 ATOM 6982 C CD2 . LEU B 1 373 ? -53.638 -2.069 263.168 1.00 40.68 ? 373 LEU B CD2 1 ATOM 6983 N N . GLY B 1 374 ? -53.511 2.532 264.061 1.00 28.72 ? 374 GLY B N 1 ATOM 6984 C CA . GLY B 1 374 ? -53.438 3.792 264.771 1.00 32.24 ? 374 GLY B CA 1 ATOM 6985 C C . GLY B 1 374 ? -52.846 3.628 266.155 1.00 33.19 ? 374 GLY B C 1 ATOM 6986 O O . GLY B 1 374 ? -52.228 4.554 266.689 1.00 42.14 ? 374 GLY B O 1 ATOM 6987 N N . LYS B 1 375 ? -53.035 2.447 266.741 1.00 27.32 ? 375 LYS B N 1 ATOM 6988 C CA . LYS B 1 375 ? -52.491 2.120 268.051 1.00 28.84 ? 375 LYS B CA 1 ATOM 6989 C C . LYS B 1 375 ? -52.224 0.623 268.114 1.00 27.80 ? 375 LYS B C 1 ATOM 6990 O O . LYS B 1 375 ? -52.914 -0.173 267.472 1.00 39.04 ? 375 LYS B O 1 ATOM 6991 C CB . LYS B 1 375 ? -53.439 2.537 269.184 1.00 27.85 ? 375 LYS B CB 1 ATOM 6992 C CG . LYS B 1 375 ? -53.383 4.015 269.536 1.00 33.62 ? 375 LYS B CG 1 ATOM 6993 C CD . LYS B 1 375 ? -54.620 4.456 270.297 1.00 42.70 ? 375 LYS B CD 1 ATOM 6994 C CE . LYS B 1 375 ? -55.762 4.764 269.345 1.00 29.92 ? 375 LYS B CE 1 ATOM 6995 N NZ . LYS B 1 375 ? -57.033 4.117 269.768 1.00 27.47 ? 375 LYS B NZ 1 ATOM 6996 N N . ILE B 1 376 ? -51.212 0.250 268.893 1.00 26.84 ? 376 ILE B N 1 ATOM 6997 C CA . ILE B 1 376 ? -50.824 -1.143 269.083 1.00 25.63 ? 376 ILE B CA 1 ATOM 6998 C C . ILE B 1 376 ? -50.869 -1.439 270.574 1.00 24.35 ? 376 ILE B C 1 ATOM 6999 O O . ILE B 1 376 ? -50.121 -0.838 271.355 1.00 26.13 ? 376 ILE B O 1 ATOM 7000 C CB . ILE B 1 376 ? -49.428 -1.433 268.510 1.00 26.43 ? 376 ILE B CB 1 ATOM 7001 C CG1 . ILE B 1 376 ? -49.408 -1.184 267.000 1.00 25.71 ? 376 ILE B CG1 1 ATOM 7002 C CG2 . ILE B 1 376 ? -49.011 -2.859 268.825 1.00 23.93 ? 376 ILE B CG2 1 ATOM 7003 C CD1 . ILE B 1 376 ? -48.067 -1.457 266.356 1.00 26.85 ? 376 ILE B CD1 1 ATOM 7004 N N . PHE B 1 377 ? -51.743 -2.363 270.968 1.00 24.37 ? 377 PHE B N 1 ATOM 7005 C CA . PHE B 1 377 ? -51.927 -2.711 272.376 1.00 23.70 ? 377 PHE B CA 1 ATOM 7006 C C . PHE B 1 377 ? -50.978 -3.849 272.724 1.00 25.95 ? 377 PHE B C 1 ATOM 7007 O O . PHE B 1 377 ? -51.285 -5.026 272.537 1.00 29.46 ? 377 PHE B O 1 ATOM 7008 C CB . PHE B 1 377 ? -53.378 -3.083 272.652 1.00 22.47 ? 377 PHE B CB 1 ATOM 7009 C CG . PHE B 1 377 ? -54.344 -1.952 272.443 1.00 25.80 ? 377 PHE B CG 1 ATOM 7010 C CD1 . PHE B 1 377 ? -54.351 -0.864 273.299 1.00 24.53 ? 377 PHE B CD1 1 ATOM 7011 C CD2 . PHE B 1 377 ? -55.251 -1.982 271.398 1.00 26.20 ? 377 PHE B CD2 1 ATOM 7012 C CE1 . PHE B 1 377 ? -55.238 0.177 273.113 1.00 25.94 ? 377 PHE B CE1 1 ATOM 7013 C CE2 . PHE B 1 377 ? -56.143 -0.944 271.208 1.00 25.63 ? 377 PHE B CE2 1 ATOM 7014 C CZ . PHE B 1 377 ? -56.136 0.137 272.065 1.00 30.75 ? 377 PHE B CZ 1 ATOM 7015 N N . LEU B 1 378 ? -49.807 -3.493 273.248 1.00 25.72 ? 378 LEU B N 1 ATOM 7016 C CA . LEU B 1 378 ? -48.804 -4.487 273.617 1.00 22.09 ? 378 LEU B CA 1 ATOM 7017 C C . LEU B 1 378 ? -49.242 -5.195 274.893 1.00 26.92 ? 378 LEU B C 1 ATOM 7018 O O . LEU B 1 378 ? -49.197 -4.614 275.982 1.00 38.90 ? 378 LEU B O 1 ATOM 7019 C CB . LEU B 1 378 ? -47.444 -3.820 273.797 1.00 23.54 ? 378 LEU B CB 1 ATOM 7020 C CG . LEU B 1 378 ? -46.290 -4.741 274.189 1.00 26.97 ? 378 LEU B CG 1 ATOM 7021 C CD1 . LEU B 1 378 ? -45.993 -5.717 273.065 1.00 32.03 ? 378 LEU B CD1 1 ATOM 7022 C CD2 . LEU B 1 378 ? -45.054 -3.932 274.541 1.00 26.34 ? 378 LEU B CD2 1 ATOM 7023 N N . MET B 1 379 ? -49.665 -6.452 274.761 1.00 29.25 ? 379 MET B N 1 ATOM 7024 C CA . MET B 1 379 ? -50.170 -7.244 275.882 1.00 26.17 ? 379 MET B CA 1 ATOM 7025 C C . MET B 1 379 ? -49.001 -7.641 276.780 1.00 28.46 ? 379 MET B C 1 ATOM 7026 O O . MET B 1 379 ? -48.441 -8.736 276.689 1.00 28.36 ? 379 MET B O 1 ATOM 7027 C CB . MET B 1 379 ? -50.922 -8.464 275.365 1.00 20.78 ? 379 MET B CB 1 ATOM 7028 C CG . MET B 1 379 ? -52.187 -8.119 274.597 1.00 20.04 ? 379 MET B CG 1 ATOM 7029 S SD . MET B 1 379 ? -52.908 -9.541 273.762 1.00 17.67 ? 379 MET B SD 1 ATOM 7030 C CE . MET B 1 379 ? -52.659 -10.816 274.991 1.00 38.98 ? 379 MET B CE 1 ATOM 7031 N N . SER B 1 380 ? -48.636 -6.727 277.678 1.00 27.62 ? 380 SER B N 1 ATOM 7032 C CA . SER B 1 380 ? -47.480 -6.916 278.555 1.00 27.44 ? 380 SER B CA 1 ATOM 7033 C C . SER B 1 380 ? -47.903 -7.543 279.885 1.00 25.61 ? 380 SER B C 1 ATOM 7034 O O . SER B 1 380 ? -47.710 -6.987 280.966 1.00 24.95 ? 380 SER B O 1 ATOM 7035 C CB . SER B 1 380 ? -46.763 -5.589 278.773 1.00 29.60 ? 380 SER B CB 1 ATOM 7036 O OG . SER B 1 380 ? -47.637 -4.626 279.336 1.00 26.23 ? 380 SER B OG 1 ATOM 7037 N N . TYR B 1 381 ? -48.487 -8.732 279.786 1.00 26.27 ? 381 TYR B N 1 ATOM 7038 C CA . TYR B 1 381 ? -48.897 -9.489 280.962 1.00 32.12 ? 381 TYR B CA 1 ATOM 7039 C C . TYR B 1 381 ? -48.960 -10.965 280.588 1.00 37.71 ? 381 TYR B C 1 ATOM 7040 O O . TYR B 1 381 ? -48.717 -11.346 279.440 1.00 40.10 ? 381 TYR B O 1 ATOM 7041 C CB . TYR B 1 381 ? -50.232 -8.979 281.514 1.00 38.30 ? 381 TYR B CB 1 ATOM 7042 C CG . TYR B 1 381 ? -51.234 -8.580 280.456 1.00 26.26 ? 381 TYR B CG 1 ATOM 7043 C CD1 . TYR B 1 381 ? -52.004 -9.533 279.803 1.00 32.76 ? 381 TYR B CD1 1 ATOM 7044 C CD2 . TYR B 1 381 ? -51.416 -7.246 280.116 1.00 26.02 ? 381 TYR B CD2 1 ATOM 7045 C CE1 . TYR B 1 381 ? -52.923 -9.168 278.836 1.00 35.73 ? 381 TYR B CE1 1 ATOM 7046 C CE2 . TYR B 1 381 ? -52.331 -6.872 279.152 1.00 28.76 ? 381 TYR B CE2 1 ATOM 7047 C CZ . TYR B 1 381 ? -53.082 -7.837 278.516 1.00 29.96 ? 381 TYR B CZ 1 ATOM 7048 O OH . TYR B 1 381 ? -53.995 -7.467 277.555 1.00 24.93 ? 381 TYR B OH 1 ATOM 7049 N N . ASP B 1 382 ? -49.286 -11.795 281.582 1.00 30.11 ? 382 ASP B N 1 ATOM 7050 C CA . ASP B 1 382 ? -49.320 -13.250 281.426 1.00 27.04 ? 382 ASP B CA 1 ATOM 7051 C C . ASP B 1 382 ? -47.963 -13.797 280.988 1.00 26.24 ? 382 ASP B C 1 ATOM 7052 O O . ASP B 1 382 ? -47.879 -14.749 280.211 1.00 29.17 ? 382 ASP B O 1 ATOM 7053 C CB . ASP B 1 382 ? -50.422 -13.684 280.456 1.00 28.06 ? 382 ASP B CB 1 ATOM 7054 C CG . ASP B 1 382 ? -51.811 -13.390 280.984 1.00 29.52 ? 382 ASP B CG 1 ATOM 7055 O OD1 . ASP B 1 382 ? -51.995 -13.411 282.218 1.00 29.90 ? 382 ASP B OD1 1 ATOM 7056 O OD2 . ASP B 1 382 ? -52.719 -13.136 280.166 1.00 40.80 ? 382 ASP B OD2 1 ATOM 7057 N N . PHE B 1 383 ? -46.888 -13.183 281.489 1.00 28.64 ? 383 PHE B N 1 ATOM 7058 C CA . PHE B 1 383 ? -45.554 -13.718 281.237 1.00 36.43 ? 383 PHE B CA 1 ATOM 7059 C C . PHE B 1 383 ? -45.363 -15.057 281.934 1.00 30.94 ? 383 PHE B C 1 ATOM 7060 O O . PHE B 1 383 ? -44.795 -15.992 281.357 1.00 29.05 ? 383 PHE B O 1 ATOM 7061 C CB . PHE B 1 383 ? -44.488 -12.722 281.697 1.00 35.06 ? 383 PHE B CB 1 ATOM 7062 C CG . PHE B 1 383 ? -44.439 -11.464 280.881 1.00 27.10 ? 383 PHE B CG 1 ATOM 7063 C CD1 . PHE B 1 383 ? -44.595 -11.506 279.507 1.00 27.13 ? 383 PHE B CD1 1 ATOM 7064 C CD2 . PHE B 1 383 ? -44.238 -10.237 281.490 1.00 27.12 ? 383 PHE B CD2 1 ATOM 7065 C CE1 . PHE B 1 383 ? -44.549 -10.351 278.755 1.00 25.30 ? 383 PHE B CE1 1 ATOM 7066 C CE2 . PHE B 1 383 ? -44.192 -9.077 280.743 1.00 27.14 ? 383 PHE B CE2 1 ATOM 7067 C CZ . PHE B 1 383 ? -44.348 -9.134 279.374 1.00 25.66 ? 383 PHE B CZ 1 ATOM 7068 N N . LYS B 1 384 ? -45.829 -15.166 283.175 1.00 32.89 ? 384 LYS B N 1 ATOM 7069 C CA . LYS B 1 384 ? -45.746 -16.392 283.949 1.00 31.48 ? 384 LYS B CA 1 ATOM 7070 C C . LYS B 1 384 ? -47.129 -16.724 284.490 1.00 29.79 ? 384 LYS B C 1 ATOM 7071 O O . LYS B 1 384 ? -47.977 -15.846 284.658 1.00 31.14 ? 384 LYS B O 1 ATOM 7072 C CB . LYS B 1 384 ? -44.742 -16.259 285.101 1.00 29.89 ? 384 LYS B CB 1 ATOM 7073 C CG . LYS B 1 384 ? -43.375 -15.748 284.673 1.00 31.86 ? 384 LYS B CG 1 ATOM 7074 C CD . LYS B 1 384 ? -42.650 -16.728 283.767 1.00 42.51 ? 384 LYS B CD 1 ATOM 7075 C CE . LYS B 1 384 ? -41.250 -16.228 283.443 1.00 38.43 ? 384 LYS B CE 1 ATOM 7076 N NZ . LYS B 1 384 ? -40.471 -17.215 282.650 1.00 41.07 ? 384 LYS B NZ 1 ATOM 7077 N N . GLY B 1 385 ? -47.353 -18.007 284.762 1.00 30.47 ? 385 GLY B N 1 ATOM 7078 C CA . GLY B 1 385 ? -48.658 -18.426 285.231 1.00 30.81 ? 385 GLY B CA 1 ATOM 7079 C C . GLY B 1 385 ? -48.604 -19.781 285.901 1.00 36.44 ? 385 GLY B C 1 ATOM 7080 O O . GLY B 1 385 ? -47.547 -20.405 286.019 1.00 28.65 ? 385 GLY B O 1 ATOM 7081 N N . ALA B 1 386 ? -49.779 -20.230 286.341 1.00 37.58 ? 386 ALA B N 1 ATOM 7082 C CA . ALA B 1 386 ? -49.924 -21.508 287.025 1.00 28.86 ? 386 ALA B CA 1 ATOM 7083 C C . ALA B 1 386 ? -49.895 -22.699 286.078 1.00 29.99 ? 386 ALA B C 1 ATOM 7084 O O . ALA B 1 386 ? -49.967 -23.841 286.545 1.00 29.77 ? 386 ALA B O 1 ATOM 7085 C CB . ALA B 1 386 ? -51.223 -21.524 287.834 1.00 29.23 ? 386 ALA B CB 1 ATOM 7086 N N . TRP B 1 387 ? -49.796 -22.466 284.767 1.00 28.76 ? 387 TRP B N 1 ATOM 7087 C CA . TRP B 1 387 ? -49.664 -23.568 283.823 1.00 30.16 ? 387 TRP B CA 1 ATOM 7088 C C . TRP B 1 387 ? -48.351 -24.318 283.995 1.00 38.63 ? 387 TRP B C 1 ATOM 7089 O O . TRP B 1 387 ? -48.217 -25.435 283.484 1.00 58.60 ? 387 TRP B O 1 ATOM 7090 C CB . TRP B 1 387 ? -49.789 -23.047 282.391 1.00 30.13 ? 387 TRP B CB 1 ATOM 7091 C CG . TRP B 1 387 ? -48.914 -21.866 282.108 1.00 31.06 ? 387 TRP B CG 1 ATOM 7092 C CD1 . TRP B 1 387 ? -47.573 -21.879 281.857 1.00 32.65 ? 387 TRP B CD1 1 ATOM 7093 C CD2 . TRP B 1 387 ? -49.320 -20.494 282.046 1.00 34.18 ? 387 TRP B CD2 1 ATOM 7094 N NE1 . TRP B 1 387 ? -47.119 -20.601 281.643 1.00 34.75 ? 387 TRP B NE1 1 ATOM 7095 C CE2 . TRP B 1 387 ? -48.172 -19.731 281.753 1.00 33.84 ? 387 TRP B CE2 1 ATOM 7096 C CE3 . TRP B 1 387 ? -50.543 -19.836 282.209 1.00 37.78 ? 387 TRP B CE3 1 ATOM 7097 C CZ2 . TRP B 1 387 ? -48.211 -18.345 281.620 1.00 42.06 ? 387 TRP B CZ2 1 ATOM 7098 C CZ3 . TRP B 1 387 ? -50.579 -18.460 282.077 1.00 32.78 ? 387 TRP B CZ3 1 ATOM 7099 C CH2 . TRP B 1 387 ? -49.421 -17.730 281.786 1.00 38.42 ? 387 TRP B CH2 1 ATOM 7100 N N . SER B 1 388 ? -47.384 -23.732 284.698 1.00 35.08 ? 388 SER B N 1 ATOM 7101 C CA . SER B 1 388 ? -46.110 -24.384 284.978 1.00 33.60 ? 388 SER B CA 1 ATOM 7102 C C . SER B 1 388 ? -45.724 -24.089 286.418 1.00 34.43 ? 388 SER B C 1 ATOM 7103 O O . SER B 1 388 ? -45.498 -22.929 286.775 1.00 38.25 ? 388 SER B O 1 ATOM 7104 C CB . SER B 1 388 ? -45.016 -23.904 284.019 1.00 34.65 ? 388 SER B CB 1 ATOM 7105 O OG . SER B 1 388 ? -43.760 -24.466 284.358 1.00 35.75 ? 388 SER B OG 1 ATOM 7106 N N . ASN B 1 389 ? -45.658 -25.133 287.243 1.00 36.39 ? 389 ASN B N 1 ATOM 7107 C CA . ASN B 1 389 ? -45.210 -24.983 288.621 1.00 34.20 ? 389 ASN B CA 1 ATOM 7108 C C . ASN B 1 389 ? -43.704 -24.798 288.733 1.00 37.13 ? 389 ASN B C 1 ATOM 7109 O O . ASN B 1 389 ? -43.220 -24.437 289.811 1.00 41.79 ? 389 ASN B O 1 ATOM 7110 C CB . ASN B 1 389 ? -45.637 -26.195 289.451 1.00 37.75 ? 389 ASN B CB 1 ATOM 7111 C CG . ASN B 1 389 ? -47.141 -26.305 289.591 1.00 44.09 ? 389 ASN B CG 1 ATOM 7112 O OD1 . ASN B 1 389 ? -47.874 -25.364 289.291 1.00 64.16 ? 389 ASN B OD1 1 ATOM 7113 N ND2 . ASN B 1 389 ? -47.609 -27.458 290.055 1.00 57.09 ? 389 ASN B ND2 1 ATOM 7114 N N . THR B 1 390 ? -42.958 -25.039 287.656 1.00 36.37 ? 390 THR B N 1 ATOM 7115 C CA . THR B 1 390 ? -41.510 -24.881 287.662 1.00 32.77 ? 390 THR B CA 1 ATOM 7116 C C . THR B 1 390 ? -41.092 -23.458 287.308 1.00 33.16 ? 390 THR B C 1 ATOM 7117 O O . THR B 1 390 ? -40.334 -22.826 288.050 1.00 44.21 ? 390 THR B O 1 ATOM 7118 C CB . THR B 1 390 ? -40.869 -25.873 286.686 1.00 34.38 ? 390 THR B CB 1 ATOM 7119 O OG1 . THR B 1 390 ? -41.353 -25.621 285.361 1.00 36.43 ? 390 THR B OG1 1 ATOM 7120 C CG2 . THR B 1 390 ? -41.210 -27.302 287.079 1.00 37.79 ? 390 THR B CG2 1 ATOM 7121 N N . ASP B 1 391 ? -41.583 -22.942 286.180 1.00 33.64 ? 391 ASP B N 1 ATOM 7122 C CA . ASP B 1 391 ? -41.208 -21.613 285.698 1.00 35.96 ? 391 ASP B CA 1 ATOM 7123 C C . ASP B 1 391 ? -42.003 -20.565 286.474 1.00 32.28 ? 391 ASP B C 1 ATOM 7124 O O . ASP B 1 391 ? -42.989 -19.997 285.998 1.00 32.02 ? 391 ASP B O 1 ATOM 7125 C CB . ASP B 1 391 ? -41.444 -21.502 284.197 1.00 38.42 ? 391 ASP B CB 1 ATOM 7126 C CG . ASP B 1 391 ? -40.965 -20.182 283.625 1.00 42.35 ? 391 ASP B CG 1 ATOM 7127 O OD1 . ASP B 1 391 ? -40.187 -19.481 284.306 1.00 72.97 ? 391 ASP B OD1 1 ATOM 7128 O OD2 . ASP B 1 391 ? -41.367 -19.845 282.492 1.00 41.49 ? 391 ASP B OD2 1 ATOM 7129 N N . LEU B 1 392 ? -41.556 -20.308 287.699 1.00 31.04 ? 392 LEU B N 1 ATOM 7130 C CA . LEU B 1 392 ? -42.159 -19.288 288.543 1.00 29.95 ? 392 LEU B CA 1 ATOM 7131 C C . LEU B 1 392 ? -41.496 -17.944 288.275 1.00 31.55 ? 392 LEU B C 1 ATOM 7132 O O . LEU B 1 392 ? -40.265 -17.847 288.240 1.00 34.05 ? 392 LEU B O 1 ATOM 7133 C CB . LEU B 1 392 ? -42.029 -19.657 290.021 1.00 30.25 ? 392 LEU B CB 1 ATOM 7134 C CG . LEU B 1 392 ? -42.550 -21.030 290.447 1.00 30.95 ? 392 LEU B CG 1 ATOM 7135 C CD1 . LEU B 1 392 ? -42.572 -21.142 291.963 1.00 32.71 ? 392 LEU B CD1 1 ATOM 7136 C CD2 . LEU B 1 392 ? -43.931 -21.278 289.872 1.00 36.76 ? 392 LEU B CD2 1 ATOM 7137 N N . GLY B 1 393 ? -42.311 -16.916 288.085 1.00 32.82 ? 393 GLY B N 1 ATOM 7138 C CA . GLY B 1 393 ? -41.785 -15.595 287.819 1.00 33.87 ? 393 GLY B CA 1 ATOM 7139 C C . GLY B 1 393 ? -42.883 -14.558 287.868 1.00 34.21 ? 393 GLY B C 1 ATOM 7140 O O . GLY B 1 393 ? -43.986 -14.815 288.352 1.00 39.08 ? 393 GLY B O 1 ATOM 7141 N N . TYR B 1 394 ? -42.565 -13.374 287.352 1.00 33.87 ? 394 TYR B N 1 ATOM 7142 C CA . TYR B 1 394 ? -43.522 -12.277 287.333 1.00 32.56 ? 394 TYR B CA 1 ATOM 7143 C C . TYR B 1 394 ? -44.494 -12.442 286.173 1.00 31.78 ? 394 TYR B C 1 ATOM 7144 O O . TYR B 1 394 ? -44.079 -12.607 285.021 1.00 31.51 ? 394 TYR B O 1 ATOM 7145 C CB . TYR B 1 394 ? -42.800 -10.933 287.228 1.00 30.11 ? 394 TYR B CB 1 ATOM 7146 C CG . TYR B 1 394 ? -41.955 -10.590 288.432 1.00 29.27 ? 394 TYR B CG 1 ATOM 7147 C CD1 . TYR B 1 394 ? -42.178 -11.200 289.658 1.00 34.94 ? 394 TYR B CD1 1 ATOM 7148 C CD2 . TYR B 1 394 ? -40.941 -9.646 288.346 1.00 28.90 ? 394 TYR B CD2 1 ATOM 7149 C CE1 . TYR B 1 394 ? -41.410 -10.887 290.760 1.00 33.50 ? 394 TYR B CE1 1 ATOM 7150 C CE2 . TYR B 1 394 ? -40.169 -9.325 289.446 1.00 31.22 ? 394 TYR B CE2 1 ATOM 7151 C CZ . TYR B 1 394 ? -40.408 -9.950 290.650 1.00 29.64 ? 394 TYR B CZ 1 ATOM 7152 O OH . TYR B 1 394 ? -39.644 -9.639 291.752 1.00 26.65 ? 394 TYR B OH 1 ATOM 7153 N N . GLN B 1 395 ? -45.791 -12.401 286.482 1.00 28.80 ? 395 GLN B N 1 ATOM 7154 C CA . GLN B 1 395 ? -46.802 -12.437 285.431 1.00 27.19 ? 395 GLN B CA 1 ATOM 7155 C C . GLN B 1 395 ? -46.691 -11.218 284.526 1.00 30.61 ? 395 GLN B C 1 ATOM 7156 O O . GLN B 1 395 ? -46.810 -11.329 283.300 1.00 29.56 ? 395 GLN B O 1 ATOM 7157 C CB . GLN B 1 395 ? -48.196 -12.521 286.049 1.00 28.76 ? 395 GLN B CB 1 ATOM 7158 C CG . GLN B 1 395 ? -49.299 -11.972 285.164 1.00 28.68 ? 395 GLN B CG 1 ATOM 7159 C CD . GLN B 1 395 ? -50.511 -11.533 285.954 1.00 35.67 ? 395 GLN B CD 1 ATOM 7160 O OE1 . GLN B 1 395 ? -50.942 -12.215 286.882 1.00 66.48 ? 395 GLN B OE1 1 ATOM 7161 N NE2 . GLN B 1 395 ? -51.067 -10.386 285.592 1.00 31.84 ? 395 GLN B NE2 1 ATOM 7162 N N . THR B 1 396 ? -46.465 -10.045 285.113 1.00 33.86 ? 396 THR B N 1 ATOM 7163 C CA . THR B 1 396 ? -46.264 -8.825 284.348 1.00 27.03 ? 396 THR B CA 1 ATOM 7164 C C . THR B 1 396 ? -45.260 -7.949 285.082 1.00 27.40 ? 396 THR B C 1 ATOM 7165 O O . THR B 1 396 ? -45.302 -7.837 286.311 1.00 25.58 ? 396 THR B O 1 ATOM 7166 C CB . THR B 1 396 ? -47.581 -8.071 284.124 1.00 25.35 ? 396 THR B CB 1 ATOM 7167 O OG1 . THR B 1 396 ? -47.321 -6.841 283.436 1.00 26.97 ? 396 THR B OG1 1 ATOM 7168 C CG2 . THR B 1 396 ? -48.277 -7.780 285.448 1.00 30.00 ? 396 THR B CG2 1 ATOM 7169 N N . THR B 1 397 ? -44.353 -7.343 284.321 1.00 35.91 ? 397 THR B N 1 ATOM 7170 C CA . THR B 1 397 ? -43.294 -6.527 284.896 1.00 29.09 ? 397 THR B CA 1 ATOM 7171 C C . THR B 1 397 ? -42.700 -5.652 283.805 1.00 26.86 ? 397 THR B C 1 ATOM 7172 O O . THR B 1 397 ? -42.802 -5.958 282.614 1.00 26.43 ? 397 THR B O 1 ATOM 7173 C CB . THR B 1 397 ? -42.202 -7.388 285.537 1.00 27.43 ? 397 THR B CB 1 ATOM 7174 O OG1 . THR B 1 397 ? -41.121 -6.549 285.957 1.00 26.61 ? 397 THR B OG1 1 ATOM 7175 C CG2 . THR B 1 397 ? -41.684 -8.417 284.545 1.00 27.51 ? 397 THR B CG2 1 ATOM 7176 N N . VAL B 1 398 ? -42.068 -4.560 284.231 1.00 27.93 ? 398 VAL B N 1 ATOM 7177 C CA . VAL B 1 398 ? -41.427 -3.650 283.286 1.00 28.65 ? 398 VAL B CA 1 ATOM 7178 C C . VAL B 1 398 ? -40.038 -4.153 282.915 1.00 29.62 ? 398 VAL B C 1 ATOM 7179 O O . VAL B 1 398 ? -39.736 -4.386 281.739 1.00 27.92 ? 398 VAL B O 1 ATOM 7180 C CB . VAL B 1 398 ? -41.372 -2.224 283.863 1.00 26.39 ? 398 VAL B CB 1 ATOM 7181 C CG1 . VAL B 1 398 ? -40.805 -1.261 282.833 1.00 27.32 ? 398 VAL B CG1 1 ATOM 7182 C CG2 . VAL B 1 398 ? -42.754 -1.780 284.310 1.00 26.31 ? 398 VAL B CG2 1 ATOM 7183 N N . TYR B 1 399 ? -39.177 -4.326 283.911 1.00 28.83 ? 399 TYR B N 1 ATOM 7184 C CA . TYR B 1 399 ? -37.811 -4.784 283.713 1.00 30.84 ? 399 TYR B CA 1 ATOM 7185 C C . TYR B 1 399 ? -37.674 -6.224 284.195 1.00 33.76 ? 399 TYR B C 1 ATOM 7186 O O . TYR B 1 399 ? -38.646 -6.867 284.602 1.00 32.83 ? 399 TYR B O 1 ATOM 7187 C CB . TYR B 1 399 ? -36.827 -3.866 284.440 1.00 31.40 ? 399 TYR B CB 1 ATOM 7188 C CG . TYR B 1 399 ? -36.929 -2.417 284.029 1.00 28.50 ? 399 TYR B CG 1 ATOM 7189 C CD1 . TYR B 1 399 ? -36.396 -1.978 282.826 1.00 27.53 ? 399 TYR B CD1 1 ATOM 7190 C CD2 . TYR B 1 399 ? -37.561 -1.489 284.844 1.00 34.21 ? 399 TYR B CD2 1 ATOM 7191 C CE1 . TYR B 1 399 ? -36.489 -0.654 282.449 1.00 28.52 ? 399 TYR B CE1 1 ATOM 7192 C CE2 . TYR B 1 399 ? -37.658 -0.163 284.473 1.00 30.22 ? 399 TYR B CE2 1 ATOM 7193 C CZ . TYR B 1 399 ? -37.121 0.249 283.274 1.00 31.26 ? 399 TYR B CZ 1 ATOM 7194 O OH . TYR B 1 399 ? -37.215 1.569 282.899 1.00 52.30 ? 399 TYR B OH 1 ATOM 7195 N N . ALA B 1 400 ? -36.446 -6.730 284.145 1.00 42.72 ? 400 ALA B N 1 ATOM 7196 C CA . ALA B 1 400 ? -36.184 -8.092 284.578 1.00 34.82 ? 400 ALA B CA 1 ATOM 7197 C C . ALA B 1 400 ? -36.109 -8.165 286.102 1.00 31.16 ? 400 ALA B C 1 ATOM 7198 O O . ALA B 1 400 ? -35.642 -7.226 286.751 1.00 40.67 ? 400 ALA B O 1 ATOM 7199 C CB . ALA B 1 400 ? -34.884 -8.601 283.969 1.00 44.63 ? 400 ALA B CB 1 ATOM 7200 N N . PRO B 1 401 ? -36.565 -9.271 286.692 1.00 29.31 ? 401 PRO B N 1 ATOM 7201 C CA . PRO B 1 401 ? -36.624 -9.371 288.157 1.00 30.11 ? 401 PRO B CA 1 ATOM 7202 C C . PRO B 1 401 ? -35.256 -9.219 288.807 1.00 35.75 ? 401 PRO B C 1 ATOM 7203 O O . PRO B 1 401 ? -34.205 -9.286 288.166 1.00 36.98 ? 401 PRO B O 1 ATOM 7204 C CB . PRO B 1 401 ? -37.196 -10.773 288.393 1.00 31.20 ? 401 PRO B CB 1 ATOM 7205 C CG . PRO B 1 401 ? -37.957 -11.079 287.152 1.00 31.06 ? 401 PRO B CG 1 ATOM 7206 C CD . PRO B 1 401 ? -37.197 -10.427 286.034 1.00 33.41 ? 401 PRO B CD 1 ATOM 7207 N N . SER B 1 402 ? -35.288 -9.010 290.126 1.00 48.79 ? 402 SER B N 1 ATOM 7208 C CA . SER B 1 402 ? -34.051 -8.879 290.891 1.00 34.60 ? 402 SER B CA 1 ATOM 7209 C C . SER B 1 402 ? -33.306 -10.205 290.970 1.00 37.86 ? 402 SER B C 1 ATOM 7210 O O . SER B 1 402 ? -32.072 -10.237 290.896 1.00 63.81 ? 402 SER B O 1 ATOM 7211 C CB . SER B 1 402 ? -34.360 -8.352 292.292 1.00 36.15 ? 402 SER B CB 1 ATOM 7212 O OG . SER B 1 402 ? -33.387 -8.782 293.228 1.00 34.87 ? 402 SER B OG 1 ATOM 7213 N N . TRP B 1 403 ? -34.036 -11.308 291.120 1.00 33.90 ? 403 TRP B N 1 ATOM 7214 C CA . TRP B 1 403 ? -33.441 -12.635 291.213 1.00 35.22 ? 403 TRP B CA 1 ATOM 7215 C C . TRP B 1 403 ? -33.121 -13.243 289.852 1.00 38.60 ? 403 TRP B C 1 ATOM 7216 O O . TRP B 1 403 ? -32.600 -14.363 289.800 1.00 71.39 ? 403 TRP B O 1 ATOM 7217 C CB . TRP B 1 403 ? -34.375 -13.562 291.996 1.00 46.11 ? 403 TRP B CB 1 ATOM 7218 C CG . TRP B 1 403 ? -35.818 -13.348 291.662 1.00 32.53 ? 403 TRP B CG 1 ATOM 7219 C CD1 . TRP B 1 403 ? -36.709 -12.568 292.339 1.00 30.99 ? 403 TRP B CD1 1 ATOM 7220 C CD2 . TRP B 1 403 ? -36.538 -13.917 290.563 1.00 30.55 ? 403 TRP B CD2 1 ATOM 7221 N NE1 . TRP B 1 403 ? -37.938 -12.615 291.730 1.00 32.28 ? 403 TRP B NE1 1 ATOM 7222 C CE2 . TRP B 1 403 ? -37.860 -13.438 290.637 1.00 33.44 ? 403 TRP B CE2 1 ATOM 7223 C CE3 . TRP B 1 403 ? -36.193 -14.787 289.525 1.00 31.38 ? 403 TRP B CE3 1 ATOM 7224 C CZ2 . TRP B 1 403 ? -38.837 -13.798 289.711 1.00 37.03 ? 403 TRP B CZ2 1 ATOM 7225 C CZ3 . TRP B 1 403 ? -37.164 -15.142 288.607 1.00 31.77 ? 403 TRP B CZ3 1 ATOM 7226 C CH2 . TRP B 1 403 ? -38.469 -14.650 288.707 1.00 32.48 ? 403 TRP B CH2 1 ATOM 7227 N N . ASN B 1 404 ? -33.415 -12.539 288.759 1.00 35.98 ? 404 ASN B N 1 ATOM 7228 C CA . ASN B 1 404 ? -33.081 -13.017 287.415 1.00 38.62 ? 404 ASN B CA 1 ATOM 7229 C C . ASN B 1 404 ? -33.089 -11.766 286.529 1.00 42.67 ? 404 ASN B C 1 ATOM 7230 O O . ASN B 1 404 ? -34.134 -11.372 286.014 1.00 53.60 ? 404 ASN B O 1 ATOM 7231 C CB . ASN B 1 404 ? -34.063 -14.069 286.929 1.00 40.77 ? 404 ASN B CB 1 ATOM 7232 C CG . ASN B 1 404 ? -33.723 -14.615 285.549 1.00 55.00 ? 404 ASN B CG 1 ATOM 7233 O OD1 . ASN B 1 404 ? -33.004 -13.991 284.769 1.00 65.17 ? 404 ASN B OD1 1 ATOM 7234 N ND2 . ASN B 1 404 ? -34.245 -15.798 285.247 1.00 49.84 ? 404 ASN B ND2 1 ATOM 7235 N N . SER B 1 405 ? -31.913 -11.162 286.362 1.00 49.59 ? 405 SER B N 1 ATOM 7236 C CA . SER B 1 405 ? -31.804 -9.795 285.870 1.00 62.61 ? 405 SER B CA 1 ATOM 7237 C C . SER B 1 405 ? -31.747 -9.688 284.348 1.00 55.10 ? 405 SER B C 1 ATOM 7238 O O . SER B 1 405 ? -31.455 -8.604 283.833 1.00 65.15 ? 405 SER B O 1 ATOM 7239 C CB . SER B 1 405 ? -30.577 -9.116 286.481 1.00 69.13 ? 405 SER B CB 1 ATOM 7240 O OG . SER B 1 405 ? -30.220 -7.960 285.745 1.00 80.39 ? 405 SER B OG 1 ATOM 7241 N N . GLU B 1 406 ? -32.027 -10.765 283.621 1.00 52.00 ? 406 GLU B N 1 ATOM 7242 C CA . GLU B 1 406 ? -32.179 -10.704 282.167 1.00 65.34 ? 406 GLU B CA 1 ATOM 7243 C C . GLU B 1 406 ? -33.231 -11.714 281.707 1.00 69.81 ? 406 GLU B C 1 ATOM 7244 O O . GLU B 1 406 ? -32.983 -12.595 280.886 1.00 58.95 ? 406 GLU B O 1 ATOM 7245 C CB . GLU B 1 406 ? -30.845 -10.914 281.452 1.00 68.53 ? 406 GLU B CB 1 ATOM 7246 C CG . GLU B 1 406 ? -29.966 -9.662 281.333 1.00 62.41 ? 406 GLU B CG 1 ATOM 7247 C CD . GLU B 1 406 ? -30.751 -8.420 280.921 1.00 59.58 ? 406 GLU B CD 1 ATOM 7248 O OE1 . GLU B 1 406 ? -31.602 -8.518 280.013 1.00 60.43 ? 406 GLU B OE1 1 ATOM 7249 O OE2 . GLU B 1 406 ? -30.516 -7.341 281.508 1.00 62.83 ? 406 GLU B OE2 1 ATOM 7250 N N . GLU B 1 407 ? -34.442 -11.579 282.240 1.00 52.01 ? 407 GLU B N 1 ATOM 7251 C CA . GLU B 1 407 ? -35.593 -12.279 281.692 1.00 44.79 ? 407 GLU B CA 1 ATOM 7252 C C . GLU B 1 407 ? -36.072 -11.548 280.445 1.00 45.45 ? 407 GLU B C 1 ATOM 7253 O O . GLU B 1 407 ? -36.330 -10.341 280.484 1.00 71.41 ? 407 GLU B O 1 ATOM 7254 C CB . GLU B 1 407 ? -36.713 -12.360 282.728 1.00 43.49 ? 407 GLU B CB 1 ATOM 7255 C CG . GLU B 1 407 ? -38.025 -12.899 282.184 1.00 41.13 ? 407 GLU B CG 1 ATOM 7256 C CD . GLU B 1 407 ? -37.949 -14.367 281.816 1.00 39.84 ? 407 GLU B CD 1 ATOM 7257 O OE1 . GLU B 1 407 ? -37.645 -15.190 282.705 1.00 48.52 ? 407 GLU B OE1 1 ATOM 7258 O OE2 . GLU B 1 407 ? -38.189 -14.695 280.636 1.00 39.90 ? 407 GLU B OE2 1 ATOM 7259 N N . LEU B 1 408 ? -36.175 -12.272 279.332 1.00 41.20 ? 408 LEU B N 1 ATOM 7260 C CA . LEU B 1 408 ? -36.577 -11.644 278.081 1.00 38.82 ? 408 LEU B CA 1 ATOM 7261 C C . LEU B 1 408 ? -38.077 -11.404 277.986 1.00 51.47 ? 408 LEU B C 1 ATOM 7262 O O . LEU B 1 408 ? -38.516 -10.714 277.059 1.00 52.13 ? 408 LEU B O 1 ATOM 7263 C CB . LEU B 1 408 ? -36.110 -12.486 276.891 1.00 38.07 ? 408 LEU B CB 1 ATOM 7264 C CG . LEU B 1 408 ? -34.595 -12.629 276.740 1.00 44.62 ? 408 LEU B CG 1 ATOM 7265 C CD1 . LEU B 1 408 ? -34.249 -13.814 275.852 1.00 48.80 ? 408 LEU B CD1 1 ATOM 7266 C CD2 . LEU B 1 408 ? -33.986 -11.345 276.195 1.00 39.99 ? 408 LEU B CD2 1 ATOM 7267 N N . TYR B 1 409 ? -38.869 -11.946 278.909 1.00 38.71 ? 409 TYR B N 1 ATOM 7268 C CA . TYR B 1 409 ? -40.305 -11.675 278.952 1.00 33.78 ? 409 TYR B CA 1 ATOM 7269 C C . TYR B 1 409 ? -40.586 -10.556 279.954 1.00 37.81 ? 409 TYR B C 1 ATOM 7270 O O . TYR B 1 409 ? -41.089 -10.766 281.059 1.00 39.61 ? 409 TYR B O 1 ATOM 7271 C CB . TYR B 1 409 ? -41.082 -12.942 279.292 1.00 31.87 ? 409 TYR B CB 1 ATOM 7272 C CG . TYR B 1 409 ? -41.515 -13.737 278.082 1.00 32.26 ? 409 TYR B CG 1 ATOM 7273 C CD1 . TYR B 1 409 ? -41.002 -13.460 276.823 1.00 34.36 ? 409 TYR B CD1 1 ATOM 7274 C CD2 . TYR B 1 409 ? -42.453 -14.754 278.198 1.00 30.53 ? 409 TYR B CD2 1 ATOM 7275 C CE1 . TYR B 1 409 ? -41.399 -14.182 275.715 1.00 33.48 ? 409 TYR B CE1 1 ATOM 7276 C CE2 . TYR B 1 409 ? -42.857 -15.481 277.096 1.00 33.95 ? 409 TYR B CE2 1 ATOM 7277 C CZ . TYR B 1 409 ? -42.328 -15.190 275.857 1.00 35.67 ? 409 TYR B CZ 1 ATOM 7278 O OH . TYR B 1 409 ? -42.727 -15.911 274.755 1.00 29.99 ? 409 TYR B OH 1 ATOM 7279 N N . THR B 1 410 ? -40.234 -9.341 279.539 1.00 30.98 ? 410 THR B N 1 ATOM 7280 C CA . THR B 1 410 ? -40.503 -8.134 280.305 1.00 27.35 ? 410 THR B CA 1 ATOM 7281 C C . THR B 1 410 ? -41.089 -7.077 279.382 1.00 28.70 ? 410 THR B C 1 ATOM 7282 O O . THR B 1 410 ? -41.007 -7.178 278.155 1.00 29.21 ? 410 THR B O 1 ATOM 7283 C CB . THR B 1 410 ? -39.238 -7.587 280.983 1.00 33.36 ? 410 THR B CB 1 ATOM 7284 O OG1 . THR B 1 410 ? -38.296 -7.174 279.984 1.00 33.61 ? 410 THR B OG1 1 ATOM 7285 C CG2 . THR B 1 410 ? -38.607 -8.642 281.877 1.00 58.85 ? 410 THR B CG2 1 ATOM 7286 N N . THR B 1 411 ? -41.687 -6.050 279.991 1.00 29.43 ? 411 THR B N 1 ATOM 7287 C CA . THR B 1 411 ? -42.289 -4.982 279.201 1.00 28.37 ? 411 THR B CA 1 ATOM 7288 C C . THR B 1 411 ? -41.224 -4.153 278.494 1.00 26.60 ? 411 THR B C 1 ATOM 7289 O O . THR B 1 411 ? -41.419 -3.736 277.346 1.00 26.58 ? 411 THR B O 1 ATOM 7290 C CB . THR B 1 411 ? -43.158 -4.091 280.087 1.00 27.23 ? 411 THR B CB 1 ATOM 7291 O OG1 . THR B 1 411 ? -44.092 -4.903 280.810 1.00 28.63 ? 411 THR B OG1 1 ATOM 7292 C CG2 . THR B 1 411 ? -43.924 -3.085 279.243 1.00 29.12 ? 411 THR B CG2 1 ATOM 7293 N N . HIS B 1 412 ? -40.093 -3.907 279.159 1.00 26.63 ? 412 HIS B N 1 ATOM 7294 C CA . HIS B 1 412 ? -39.013 -3.144 278.540 1.00 30.55 ? 412 HIS B CA 1 ATOM 7295 C C . HIS B 1 412 ? -38.544 -3.803 277.250 1.00 30.97 ? 412 HIS B C 1 ATOM 7296 O O . HIS B 1 412 ? -38.516 -3.171 276.188 1.00 32.53 ? 412 HIS B O 1 ATOM 7297 C CB . HIS B 1 412 ? -37.849 -2.985 279.522 1.00 34.34 ? 412 HIS B CB 1 ATOM 7298 C CG . HIS B 1 412 ? -36.684 -2.227 278.962 1.00 38.49 ? 412 HIS B CG 1 ATOM 7299 N ND1 . HIS B 1 412 ? -35.876 -2.729 277.964 1.00 40.39 ? 412 HIS B ND1 1 ATOM 7300 C CD2 . HIS B 1 412 ? -36.200 -0.995 279.251 1.00 42.38 ? 412 HIS B CD2 1 ATOM 7301 C CE1 . HIS B 1 412 ? -34.942 -1.845 277.668 1.00 63.65 ? 412 HIS B CE1 1 ATOM 7302 N NE2 . HIS B 1 412 ? -35.115 -0.784 278.435 1.00 79.68 ? 412 HIS B NE2 1 ATOM 7303 N N . TYR B 1 413 ? -38.167 -5.081 277.326 1.00 31.90 ? 413 TYR B N 1 ATOM 7304 C CA . TYR B 1 413 ? -37.684 -5.778 276.139 1.00 29.93 ? 413 TYR B CA 1 ATOM 7305 C C . TYR B 1 413 ? -38.758 -5.835 275.060 1.00 28.02 ? 413 TYR B C 1 ATOM 7306 O O . TYR B 1 413 ? -38.457 -5.715 273.867 1.00 27.87 ? 413 TYR B O 1 ATOM 7307 C CB . TYR B 1 413 ? -37.219 -7.184 276.510 1.00 27.51 ? 413 TYR B CB 1 ATOM 7308 C CG . TYR B 1 413 ? -36.365 -7.837 275.451 1.00 27.10 ? 413 TYR B CG 1 ATOM 7309 C CD1 . TYR B 1 413 ? -35.009 -7.558 275.357 1.00 23.33 ? 413 TYR B CD1 1 ATOM 7310 C CD2 . TYR B 1 413 ? -36.915 -8.725 274.539 1.00 30.00 ? 413 TYR B CD2 1 ATOM 7311 C CE1 . TYR B 1 413 ? -34.223 -8.150 274.389 1.00 22.63 ? 413 TYR B CE1 1 ATOM 7312 C CE2 . TYR B 1 413 ? -36.138 -9.322 273.568 1.00 33.52 ? 413 TYR B CE2 1 ATOM 7313 C CZ . TYR B 1 413 ? -34.794 -9.032 273.496 1.00 23.81 ? 413 TYR B CZ 1 ATOM 7314 O OH . TYR B 1 413 ? -34.019 -9.626 272.528 1.00 27.30 ? 413 TYR B OH 1 ATOM 7315 N N . ALA B 1 414 ? -40.018 -6.010 275.462 1.00 28.12 ? 414 ALA B N 1 ATOM 7316 C CA . ALA B 1 414 ? -41.109 -6.032 274.494 1.00 27.82 ? 414 ALA B CA 1 ATOM 7317 C C . ALA B 1 414 ? -41.301 -4.662 273.856 1.00 38.22 ? 414 ALA B C 1 ATOM 7318 O O . ALA B 1 414 ? -41.463 -4.552 272.635 1.00 39.51 ? 414 ALA B O 1 ATOM 7319 C CB . ALA B 1 414 ? -42.396 -6.499 275.169 1.00 30.01 ? 414 ALA B CB 1 ATOM 7320 N N . VAL B 1 415 ? -41.296 -3.604 274.671 1.00 32.34 ? 415 VAL B N 1 ATOM 7321 C CA . VAL B 1 415 ? -41.371 -2.250 274.128 1.00 31.34 ? 415 VAL B CA 1 ATOM 7322 C C . VAL B 1 415 ? -40.160 -1.966 273.252 1.00 30.63 ? 415 VAL B C 1 ATOM 7323 O O . VAL B 1 415 ? -40.287 -1.422 272.148 1.00 32.79 ? 415 VAL B O 1 ATOM 7324 C CB . VAL B 1 415 ? -41.500 -1.222 275.268 1.00 33.83 ? 415 VAL B CB 1 ATOM 7325 C CG1 . VAL B 1 415 ? -41.231 0.182 274.753 1.00 33.37 ? 415 VAL B CG1 1 ATOM 7326 C CG2 . VAL B 1 415 ? -42.881 -1.299 275.901 1.00 60.81 ? 415 VAL B CG2 1 ATOM 7327 N N . ASP B 1 416 ? -38.970 -2.345 273.721 1.00 33.13 ? 416 ASP B N 1 ATOM 7328 C CA . ASP B 1 416 ? -37.758 -2.096 272.950 1.00 37.59 ? 416 ASP B CA 1 ATOM 7329 C C . ASP B 1 416 ? -37.707 -2.948 271.688 1.00 34.25 ? 416 ASP B C 1 ATOM 7330 O O . ASP B 1 416 ? -37.068 -2.555 270.706 1.00 35.20 ? 416 ASP B O 1 ATOM 7331 C CB . ASP B 1 416 ? -36.525 -2.351 273.815 1.00 33.11 ? 416 ASP B CB 1 ATOM 7332 C CG . ASP B 1 416 ? -35.366 -1.443 273.457 1.00 36.14 ? 416 ASP B CG 1 ATOM 7333 O OD1 . ASP B 1 416 ? -35.010 -0.578 274.285 1.00 37.28 ? 416 ASP B OD1 1 ATOM 7334 O OD2 . ASP B 1 416 ? -34.811 -1.595 272.349 1.00 59.69 ? 416 ASP B OD2 1 ATOM 7335 N N . ALA B 1 417 ? -38.366 -4.110 271.694 1.00 34.27 ? 417 ALA B N 1 ATOM 7336 C CA . ALA B 1 417 ? -38.386 -4.952 270.501 1.00 30.26 ? 417 ALA B CA 1 ATOM 7337 C C . ALA B 1 417 ? -39.092 -4.253 269.347 1.00 31.71 ? 417 ALA B C 1 ATOM 7338 O O . ALA B 1 417 ? -38.656 -4.346 268.194 1.00 32.87 ? 417 ALA B O 1 ATOM 7339 C CB . ALA B 1 417 ? -39.059 -6.288 270.810 1.00 34.69 ? 417 ALA B CB 1 ATOM 7340 N N . LEU B 1 418 ? -40.187 -3.549 269.639 1.00 33.15 ? 418 LEU B N 1 ATOM 7341 C CA . LEU B 1 418 ? -40.879 -2.797 268.597 1.00 36.36 ? 418 LEU B CA 1 ATOM 7342 C C . LEU B 1 418 ? -40.045 -1.611 268.132 1.00 53.19 ? 418 LEU B C 1 ATOM 7343 O O . LEU B 1 418 ? -40.031 -1.284 266.940 1.00 72.99 ? 418 LEU B O 1 ATOM 7344 C CB . LEU B 1 418 ? -42.240 -2.326 269.107 1.00 33.83 ? 418 LEU B CB 1 ATOM 7345 C CG . LEU B 1 418 ? -43.271 -3.409 269.426 1.00 32.94 ? 418 LEU B CG 1 ATOM 7346 C CD1 . LEU B 1 418 ? -44.481 -2.806 270.118 1.00 33.56 ? 418 LEU B CD1 1 ATOM 7347 C CD2 . LEU B 1 418 ? -43.685 -4.124 268.157 1.00 34.28 ? 418 LEU B CD2 1 ATOM 7348 N N . LEU B 1 419 ? -39.336 -0.962 269.059 1.00 37.24 ? 419 LEU B N 1 ATOM 7349 C CA . LEU B 1 419 ? -38.563 0.226 268.711 1.00 35.98 ? 419 LEU B CA 1 ATOM 7350 C C . LEU B 1 419 ? -37.421 -0.111 267.761 1.00 41.32 ? 419 LEU B C 1 ATOM 7351 O O . LEU B 1 419 ? -37.080 0.692 266.885 1.00 51.13 ? 419 LEU B O 1 ATOM 7352 C CB . LEU B 1 419 ? -38.024 0.888 269.978 1.00 32.90 ? 419 LEU B CB 1 ATOM 7353 C CG . LEU B 1 419 ? -39.056 1.446 270.958 1.00 34.95 ? 419 LEU B CG 1 ATOM 7354 C CD1 . LEU B 1 419 ? -38.366 2.112 272.139 1.00 26.44 ? 419 LEU B CD1 1 ATOM 7355 C CD2 . LEU B 1 419 ? -39.995 2.422 270.263 1.00 35.78 ? 419 LEU B CD2 1 ATOM 7356 N N . LYS B 1 420 ? -36.822 -1.295 267.912 1.00 43.08 ? 420 LYS B N 1 ATOM 7357 C CA . LYS B 1 420 ? -35.670 -1.664 267.096 1.00 50.07 ? 420 LYS B CA 1 ATOM 7358 C C . LYS B 1 420 ? -36.009 -1.769 265.616 1.00 59.23 ? 420 LYS B C 1 ATOM 7359 O O . LYS B 1 420 ? -35.096 -1.798 264.784 1.00 99.52 ? 420 LYS B O 1 ATOM 7360 C CB . LYS B 1 420 ? -35.081 -2.990 267.579 1.00 43.46 ? 420 LYS B CB 1 ATOM 7361 C CG . LYS B 1 420 ? -34.411 -2.925 268.939 1.00 41.79 ? 420 LYS B CG 1 ATOM 7362 C CD . LYS B 1 420 ? -32.905 -3.079 268.809 1.00 39.53 ? 420 LYS B CD 1 ATOM 7363 C CE . LYS B 1 420 ? -32.368 -4.093 269.804 1.00 37.69 ? 420 LYS B CE 1 ATOM 7364 N NZ . LYS B 1 420 ? -30.881 -4.096 269.837 1.00 38.19 ? 420 LYS B NZ 1 ATOM 7365 N N . GLN B 1 421 ? -37.291 -1.836 265.268 1.00 47.83 ? 421 GLN B N 1 ATOM 7366 C CA . GLN B 1 421 ? -37.694 -1.939 263.873 1.00 53.84 ? 421 GLN B CA 1 ATOM 7367 C C . GLN B 1 421 ? -37.987 -0.592 263.229 1.00 56.34 ? 421 GLN B C 1 ATOM 7368 O O . GLN B 1 421 ? -37.947 -0.484 261.998 1.00 59.31 ? 421 GLN B O 1 ATOM 7369 C CB . GLN B 1 421 ? -38.937 -2.821 263.747 1.00 55.93 ? 421 GLN B CB 1 ATOM 7370 C CG . GLN B 1 421 ? -39.199 -3.287 262.337 1.00 59.42 ? 421 GLN B CG 1 ATOM 7371 C CD . GLN B 1 421 ? -40.443 -4.125 262.227 1.00 83.31 ? 421 GLN B CD 1 ATOM 7372 O OE1 . GLN B 1 421 ? -41.070 -4.462 263.232 1.00 75.92 ? 421 GLN B OE1 1 ATOM 7373 N NE2 . GLN B 1 421 ? -40.826 -4.449 260.998 1.00 86.38 ? 421 GLN B NE2 1 ATOM 7374 N N . GLY B 1 422 ? -38.271 0.433 264.025 1.00 51.30 ? 422 GLY B N 1 ATOM 7375 C CA . GLY B 1 422 ? -38.763 1.695 263.513 1.00 55.89 ? 422 GLY B CA 1 ATOM 7376 C C . GLY B 1 422 ? -40.201 1.986 263.876 1.00 48.70 ? 422 GLY B C 1 ATOM 7377 O O . GLY B 1 422 ? -40.747 2.993 263.409 1.00 67.79 ? 422 GLY B O 1 ATOM 7378 N N . VAL B 1 423 ? -40.835 1.130 264.678 1.00 45.11 ? 423 VAL B N 1 ATOM 7379 C CA . VAL B 1 423 ? -42.181 1.405 265.163 1.00 45.64 ? 423 VAL B CA 1 ATOM 7380 C C . VAL B 1 423 ? -42.140 2.660 266.018 1.00 45.66 ? 423 VAL B C 1 ATOM 7381 O O . VAL B 1 423 ? -41.421 2.722 267.023 1.00 44.04 ? 423 VAL B O 1 ATOM 7382 C CB . VAL B 1 423 ? -42.728 0.209 265.948 1.00 43.64 ? 423 VAL B CB 1 ATOM 7383 C CG1 . VAL B 1 423 ? -44.075 0.550 266.567 1.00 45.85 ? 423 VAL B CG1 1 ATOM 7384 C CG2 . VAL B 1 423 ? -42.840 -1.012 265.048 1.00 62.52 ? 423 VAL B CG2 1 ATOM 7385 N N . ASP B 1 424 ? -42.896 3.673 265.613 1.00 46.23 ? 424 ASP B N 1 ATOM 7386 C CA . ASP B 1 424 ? -42.919 4.916 266.364 1.00 46.26 ? 424 ASP B CA 1 ATOM 7387 C C . ASP B 1 424 ? -43.482 4.662 267.760 1.00 42.31 ? 424 ASP B C 1 ATOM 7388 O O . ASP B 1 424 ? -44.416 3.866 267.917 1.00 54.04 ? 424 ASP B O 1 ATOM 7389 C CB . ASP B 1 424 ? -43.763 5.967 265.642 1.00 54.12 ? 424 ASP B CB 1 ATOM 7390 C CG . ASP B 1 424 ? -43.321 6.191 264.211 1.00 72.35 ? 424 ASP B CG 1 ATOM 7391 O OD1 . ASP B 1 424 ? -42.188 5.794 263.867 1.00 86.85 ? 424 ASP B OD1 1 ATOM 7392 O OD2 . ASP B 1 424 ? -44.110 6.762 263.429 1.00 56.89 ? 424 ASP B OD2 1 ATOM 7393 N N . PRO B 1 425 ? -42.939 5.308 268.796 1.00 36.79 ? 425 PRO B N 1 ATOM 7394 C CA . PRO B 1 425 ? -43.487 5.132 270.149 1.00 37.15 ? 425 PRO B CA 1 ATOM 7395 C C . PRO B 1 425 ? -44.887 5.699 270.321 1.00 43.16 ? 425 PRO B C 1 ATOM 7396 O O . PRO B 1 425 ? -45.453 5.582 271.413 1.00 37.81 ? 425 PRO B O 1 ATOM 7397 C CB . PRO B 1 425 ? -42.477 5.876 271.040 1.00 35.39 ? 425 PRO B CB 1 ATOM 7398 C CG . PRO B 1 425 ? -41.276 6.131 270.172 1.00 36.41 ? 425 PRO B CG 1 ATOM 7399 C CD . PRO B 1 425 ? -41.787 6.223 268.777 1.00 38.73 ? 425 PRO B CD 1 ATOM 7400 N N . ASN B 1 426 ? -45.459 6.307 269.280 1.00 52.64 ? 426 ASN B N 1 ATOM 7401 C CA . ASN B 1 426 ? -46.806 6.857 269.380 1.00 42.25 ? 426 ASN B CA 1 ATOM 7402 C C . ASN B 1 426 ? -47.848 5.757 269.539 1.00 39.83 ? 426 ASN B C 1 ATOM 7403 O O . ASN B 1 426 ? -48.836 5.929 270.261 1.00 59.80 ? 426 ASN B O 1 ATOM 7404 C CB . ASN B 1 426 ? -47.109 7.700 268.142 1.00 47.76 ? 426 ASN B CB 1 ATOM 7405 C CG . ASN B 1 426 ? -47.021 6.895 266.856 1.00 75.43 ? 426 ASN B CG 1 ATOM 7406 O OD1 . ASN B 1 426 ? -46.586 5.744 266.861 1.00 74.39 ? 426 ASN B OD1 1 ATOM 7407 N ND2 . ASN B 1 426 ? -47.437 7.498 265.748 1.00 59.65 ? 426 ASN B ND2 1 ATOM 7408 N N . LYS B 1 427 ? -47.645 4.621 268.876 1.00 34.76 ? 427 LYS B N 1 ATOM 7409 C CA . LYS B 1 427 ? -48.658 3.580 268.777 1.00 34.94 ? 427 LYS B CA 1 ATOM 7410 C C . LYS B 1 427 ? -48.464 2.450 269.778 1.00 36.15 ? 427 LYS B C 1 ATOM 7411 O O . LYS B 1 427 ? -49.318 1.562 269.858 1.00 37.36 ? 427 LYS B O 1 ATOM 7412 C CB . LYS B 1 427 ? -48.681 3.017 267.352 1.00 34.70 ? 427 LYS B CB 1 ATOM 7413 C CG . LYS B 1 427 ? -49.129 4.033 266.313 1.00 36.27 ? 427 LYS B CG 1 ATOM 7414 C CD . LYS B 1 427 ? -48.907 3.545 264.894 1.00 37.77 ? 427 LYS B CD 1 ATOM 7415 C CE . LYS B 1 427 ? -49.128 4.674 263.899 1.00 32.72 ? 427 LYS B CE 1 ATOM 7416 N NZ . LYS B 1 427 ? -48.879 4.244 262.498 1.00 32.97 ? 427 LYS B NZ 1 ATOM 7417 N N . ILE B 1 428 ? -47.379 2.461 270.545 1.00 40.98 ? 428 ILE B N 1 ATOM 7418 C CA . ILE B 1 428 ? -47.121 1.403 271.517 1.00 32.15 ? 428 ILE B CA 1 ATOM 7419 C C . ILE B 1 428 ? -47.872 1.724 272.803 1.00 31.01 ? 428 ILE B C 1 ATOM 7420 O O . ILE B 1 428 ? -47.613 2.744 273.450 1.00 39.04 ? 428 ILE B O 1 ATOM 7421 C CB . ILE B 1 428 ? -45.617 1.244 271.777 1.00 34.50 ? 428 ILE B CB 1 ATOM 7422 C CG1 . ILE B 1 428 ? -44.882 0.962 270.466 1.00 35.48 ? 428 ILE B CG1 1 ATOM 7423 C CG2 . ILE B 1 428 ? -45.367 0.130 272.781 1.00 32.65 ? 428 ILE B CG2 1 ATOM 7424 C CD1 . ILE B 1 428 ? -43.382 0.869 270.614 1.00 36.33 ? 428 ILE B CD1 1 ATOM 7425 N N . ILE B 1 429 ? -48.804 0.851 273.176 1.00 30.40 ? 429 ILE B N 1 ATOM 7426 C CA . ILE B 1 429 ? -49.627 1.020 274.368 1.00 28.19 ? 429 ILE B CA 1 ATOM 7427 C C . ILE B 1 429 ? -49.273 -0.095 275.343 1.00 26.58 ? 429 ILE B C 1 ATOM 7428 O O . ILE B 1 429 ? -49.513 -1.276 275.060 1.00 24.42 ? 429 ILE B O 1 ATOM 7429 C CB . ILE B 1 429 ? -51.124 1.002 274.029 1.00 24.06 ? 429 ILE B CB 1 ATOM 7430 C CG1 . ILE B 1 429 ? -51.424 1.966 272.880 1.00 25.67 ? 429 ILE B CG1 1 ATOM 7431 C CG2 . ILE B 1 429 ? -51.948 1.372 275.249 1.00 25.08 ? 429 ILE B CG2 1 ATOM 7432 C CD1 . ILE B 1 429 ? -51.108 3.407 273.194 1.00 28.17 ? 429 ILE B CD1 1 ATOM 7433 N N . VAL B 1 430 ? -48.709 0.277 276.487 1.00 25.58 ? 430 VAL B N 1 ATOM 7434 C CA . VAL B 1 430 ? -48.276 -0.699 277.481 1.00 24.33 ? 430 VAL B CA 1 ATOM 7435 C C . VAL B 1 430 ? -49.494 -1.260 278.201 1.00 23.70 ? 430 VAL B C 1 ATOM 7436 O O . VAL B 1 430 ? -50.375 -0.510 278.639 1.00 20.71 ? 430 VAL B O 1 ATOM 7437 C CB . VAL B 1 430 ? -47.287 -0.066 278.471 1.00 24.16 ? 430 VAL B CB 1 ATOM 7438 C CG1 . VAL B 1 430 ? -46.997 -1.021 279.619 1.00 25.18 ? 430 VAL B CG1 1 ATOM 7439 C CG2 . VAL B 1 430 ? -46.006 0.315 277.756 1.00 43.39 ? 430 VAL B CG2 1 ATOM 7440 N N . GLY B 1 431 ? -49.541 -2.582 278.334 1.00 26.08 ? 431 GLY B N 1 ATOM 7441 C CA . GLY B 1 431 ? -50.665 -3.241 278.968 1.00 24.25 ? 431 GLY B CA 1 ATOM 7442 C C . GLY B 1 431 ? -50.515 -3.310 280.480 1.00 22.39 ? 431 GLY B C 1 ATOM 7443 O O . GLY B 1 431 ? -49.452 -3.640 281.003 1.00 29.29 ? 431 GLY B O 1 ATOM 7444 N N . VAL B 1 432 ? -51.599 -2.983 281.172 1.00 21.41 ? 432 VAL B N 1 ATOM 7445 C CA . VAL B 1 432 ? -51.681 -3.090 282.623 1.00 21.73 ? 432 VAL B CA 1 ATOM 7446 C C . VAL B 1 432 ? -52.619 -4.240 282.955 1.00 18.97 ? 432 VAL B C 1 ATOM 7447 O O . VAL B 1 432 ? -53.744 -4.303 282.441 1.00 20.77 ? 432 VAL B O 1 ATOM 7448 C CB . VAL B 1 432 ? -52.164 -1.775 283.258 1.00 25.24 ? 432 VAL B CB 1 ATOM 7449 C CG1 . VAL B 1 432 ? -52.259 -1.917 284.769 1.00 26.93 ? 432 VAL B CG1 1 ATOM 7450 C CG2 . VAL B 1 432 ? -51.229 -0.636 282.879 1.00 29.59 ? 432 VAL B CG2 1 ATOM 7451 N N . ALA B 1 433 ? -52.153 -5.153 283.803 1.00 22.04 ? 433 ALA B N 1 ATOM 7452 C CA . ALA B 1 433 ? -52.927 -6.319 284.214 1.00 25.55 ? 433 ALA B CA 1 ATOM 7453 C C . ALA B 1 433 ? -53.687 -5.999 285.496 1.00 25.92 ? 433 ALA B C 1 ATOM 7454 O O . ALA B 1 433 ? -53.084 -5.828 286.561 1.00 51.96 ? 433 ALA B O 1 ATOM 7455 C CB . ALA B 1 433 ? -52.017 -7.528 284.408 1.00 24.51 ? 433 ALA B CB 1 ATOM 7456 N N . MET B 1 434 ? -55.016 -5.929 285.388 1.00 22.74 ? 434 MET B N 1 ATOM 7457 C CA . MET B 1 434 ? -55.900 -5.722 286.528 1.00 22.78 ? 434 MET B CA 1 ATOM 7458 C C . MET B 1 434 ? -56.220 -7.014 287.273 1.00 29.06 ? 434 MET B C 1 ATOM 7459 O O . MET B 1 434 ? -57.304 -7.137 287.862 1.00 38.91 ? 434 MET B O 1 ATOM 7460 C CB . MET B 1 434 ? -57.184 -5.027 286.073 1.00 22.65 ? 434 MET B CB 1 ATOM 7461 C CG . MET B 1 434 ? -56.973 -3.563 285.692 1.00 28.98 ? 434 MET B CG 1 ATOM 7462 S SD . MET B 1 434 ? -58.493 -2.722 285.215 1.00 9.33 ? 434 MET B SD 1 ATOM 7463 C CE . MET B 1 434 ? -57.941 -1.022 285.247 1.00 16.63 ? 434 MET B CE 1 ATOM 7464 N N . TYR B 1 435 ? -55.295 -7.973 287.278 1.00 26.18 ? 435 TYR B N 1 ATOM 7465 C CA . TYR B 1 435 ? -55.498 -9.259 287.930 1.00 23.95 ? 435 TYR B CA 1 ATOM 7466 C C . TYR B 1 435 ? -54.140 -9.823 288.336 1.00 26.34 ? 435 TYR B C 1 ATOM 7467 O O . TYR B 1 435 ? -53.089 -9.256 288.025 1.00 33.86 ? 435 TYR B O 1 ATOM 7468 C CB . TYR B 1 435 ? -56.254 -10.225 287.010 1.00 22.26 ? 435 TYR B CB 1 ATOM 7469 C CG . TYR B 1 435 ? -55.549 -10.479 285.694 1.00 23.65 ? 435 TYR B CG 1 ATOM 7470 C CD1 . TYR B 1 435 ? -55.760 -9.649 284.603 1.00 20.38 ? 435 TYR B CD1 1 ATOM 7471 C CD2 . TYR B 1 435 ? -54.671 -11.546 285.544 1.00 27.46 ? 435 TYR B CD2 1 ATOM 7472 C CE1 . TYR B 1 435 ? -55.117 -9.868 283.402 1.00 20.21 ? 435 TYR B CE1 1 ATOM 7473 C CE2 . TYR B 1 435 ? -54.020 -11.774 284.340 1.00 28.74 ? 435 TYR B CE2 1 ATOM 7474 C CZ . TYR B 1 435 ? -54.250 -10.930 283.273 1.00 25.30 ? 435 TYR B CZ 1 ATOM 7475 O OH . TYR B 1 435 ? -53.608 -11.152 282.077 1.00 24.23 ? 435 TYR B OH 1 ATOM 7476 N N . GLY B 1 436 ? -54.167 -10.958 289.027 1.00 25.46 ? 436 GLY B N 1 ATOM 7477 C CA . GLY B 1 436 ? -52.934 -11.594 289.440 1.00 24.21 ? 436 GLY B CA 1 ATOM 7478 C C . GLY B 1 436 ? -52.946 -13.100 289.289 1.00 26.76 ? 436 GLY B C 1 ATOM 7479 O O . GLY B 1 436 ? -53.875 -13.767 289.751 1.00 36.52 ? 436 GLY B O 1 ATOM 7480 N N . ARG B 1 437 ? -51.928 -13.649 288.630 1.00 28.31 ? 437 ARG B N 1 ATOM 7481 C CA . ARG B 1 437 ? -51.777 -15.091 288.505 1.00 29.79 ? 437 ARG B CA 1 ATOM 7482 C C . ARG B 1 437 ? -50.887 -15.601 289.628 1.00 31.47 ? 437 ARG B C 1 ATOM 7483 O O . ARG B 1 437 ? -49.951 -14.917 290.051 1.00 28.20 ? 437 ARG B O 1 ATOM 7484 C CB . ARG B 1 437 ? -51.183 -15.458 287.144 1.00 27.49 ? 437 ARG B CB 1 ATOM 7485 C CG . ARG B 1 437 ? -52.110 -15.158 285.978 1.00 39.19 ? 437 ARG B CG 1 ATOM 7486 C CD . ARG B 1 437 ? -51.491 -15.572 284.656 1.00 43.68 ? 437 ARG B CD 1 ATOM 7487 N NE . ARG B 1 437 ? -52.483 -15.620 283.587 1.00 28.82 ? 437 ARG B NE 1 ATOM 7488 C CZ . ARG B 1 437 ? -53.255 -16.673 283.341 1.00 29.62 ? 437 ARG B CZ 1 ATOM 7489 N NH1 . ARG B 1 437 ? -53.146 -17.762 284.087 1.00 34.46 ? 437 ARG B NH1 1 ATOM 7490 N NH2 . ARG B 1 437 ? -54.134 -16.637 282.350 1.00 33.24 ? 437 ARG B NH2 1 ATOM 7491 N N . GLY B 1 438 ? -51.187 -16.802 290.120 1.00 32.21 ? 438 GLY B N 1 ATOM 7492 C CA . GLY B 1 438 ? -50.479 -17.296 291.282 1.00 25.03 ? 438 GLY B CA 1 ATOM 7493 C C . GLY B 1 438 ? -50.427 -18.805 291.362 1.00 27.85 ? 438 GLY B C 1 ATOM 7494 O O . GLY B 1 438 ? -51.080 -19.524 290.601 1.00 30.64 ? 438 GLY B O 1 ATOM 7495 N N . TRP B 1 439 ? -49.627 -19.272 292.316 1.00 29.72 ? 439 TRP B N 1 ATOM 7496 C CA . TRP B 1 439 ? -49.454 -20.685 292.607 1.00 26.31 ? 439 TRP B CA 1 ATOM 7497 C C . TRP B 1 439 ? -49.711 -20.913 294.090 1.00 29.72 ? 439 TRP B C 1 ATOM 7498 O O . TRP B 1 439 ? -49.589 -19.998 294.908 1.00 31.93 ? 439 TRP B O 1 ATOM 7499 C CB . TRP B 1 439 ? -48.044 -21.167 292.237 1.00 25.39 ? 439 TRP B CB 1 ATOM 7500 C CG . TRP B 1 439 ? -47.610 -20.774 290.856 1.00 25.04 ? 439 TRP B CG 1 ATOM 7501 C CD1 . TRP B 1 439 ? -47.643 -21.550 289.735 1.00 28.86 ? 439 TRP B CD1 1 ATOM 7502 C CD2 . TRP B 1 439 ? -47.083 -19.504 290.450 1.00 24.05 ? 439 TRP B CD2 1 ATOM 7503 N NE1 . TRP B 1 439 ? -47.165 -20.845 288.657 1.00 27.92 ? 439 TRP B NE1 1 ATOM 7504 C CE2 . TRP B 1 439 ? -46.817 -19.586 289.069 1.00 26.86 ? 439 TRP B CE2 1 ATOM 7505 C CE3 . TRP B 1 439 ? -46.809 -18.308 291.119 1.00 24.50 ? 439 TRP B CE3 1 ATOM 7506 C CZ2 . TRP B 1 439 ? -46.290 -18.518 288.346 1.00 26.95 ? 439 TRP B CZ2 1 ATOM 7507 C CZ3 . TRP B 1 439 ? -46.288 -17.249 290.400 1.00 24.62 ? 439 TRP B CZ3 1 ATOM 7508 C CH2 . TRP B 1 439 ? -46.034 -17.361 289.028 1.00 23.86 ? 439 TRP B CH2 1 ATOM 7509 N N . THR B 1 440 ? -50.069 -22.147 294.434 1.00 32.83 ? 440 THR B N 1 ATOM 7510 C CA . THR B 1 440 ? -50.353 -22.511 295.814 1.00 38.04 ? 440 THR B CA 1 ATOM 7511 C C . THR B 1 440 ? -49.334 -23.526 296.311 1.00 49.10 ? 440 THR B C 1 ATOM 7512 O O . THR B 1 440 ? -48.785 -24.314 295.534 1.00 40.55 ? 440 THR B O 1 ATOM 7513 C CB . THR B 1 440 ? -51.771 -23.081 295.968 1.00 38.52 ? 440 THR B CB 1 ATOM 7514 O OG1 . THR B 1 440 ? -52.023 -23.370 297.349 1.00 39.14 ? 440 THR B OG1 1 ATOM 7515 C CG2 . THR B 1 440 ? -51.932 -24.355 295.155 1.00 52.76 ? 440 THR B CG2 1 ATOM 7516 N N . GLY B 1 441 ? -49.081 -23.491 297.617 1.00 50.31 ? 441 GLY B N 1 ATOM 7517 C CA . GLY B 1 441 ? -48.161 -24.433 298.236 1.00 46.79 ? 441 GLY B CA 1 ATOM 7518 C C . GLY B 1 441 ? -46.763 -24.405 297.660 1.00 41.17 ? 441 GLY B C 1 ATOM 7519 O O . GLY B 1 441 ? -46.141 -25.462 297.495 1.00 42.92 ? 441 GLY B O 1 ATOM 7520 N N . VAL B 1 442 ? -46.254 -23.216 297.345 1.00 39.57 ? 442 VAL B N 1 ATOM 7521 C CA . VAL B 1 442 ? -44.919 -23.093 296.770 1.00 39.93 ? 442 VAL B CA 1 ATOM 7522 C C . VAL B 1 442 ? -43.892 -23.495 297.822 1.00 39.85 ? 442 VAL B C 1 ATOM 7523 O O . VAL B 1 442 ? -43.763 -22.845 298.866 1.00 37.19 ? 442 VAL B O 1 ATOM 7524 C CB . VAL B 1 442 ? -44.669 -21.668 296.261 1.00 35.84 ? 442 VAL B CB 1 ATOM 7525 C CG1 . VAL B 1 442 ? -43.236 -21.523 295.780 1.00 42.56 ? 442 VAL B CG1 1 ATOM 7526 C CG2 . VAL B 1 442 ? -45.651 -21.324 295.152 1.00 35.53 ? 442 VAL B CG2 1 ATOM 7527 N N . THR B 1 443 ? -43.157 -24.570 297.549 1.00 39.85 ? 443 THR B N 1 ATOM 7528 C CA . THR B 1 443 ? -42.204 -25.137 298.493 1.00 39.11 ? 443 THR B CA 1 ATOM 7529 C C . THR B 1 443 ? -40.846 -25.291 297.817 1.00 39.66 ? 443 THR B C 1 ATOM 7530 O O . THR B 1 443 ? -40.680 -24.996 296.629 1.00 39.57 ? 443 THR B O 1 ATOM 7531 C CB . THR B 1 443 ? -42.695 -26.487 299.029 1.00 51.81 ? 443 THR B CB 1 ATOM 7532 O OG1 . THR B 1 443 ? -41.823 -26.937 300.073 1.00 49.93 ? 443 THR B OG1 1 ATOM 7533 C CG2 . THR B 1 443 ? -42.721 -27.525 297.914 1.00 56.80 ? 443 THR B CG2 1 ATOM 7534 N N . ASN B 1 444 ? -39.869 -25.761 298.599 1.00 44.50 ? 444 ASN B N 1 ATOM 7535 C CA . ASN B 1 444 ? -38.517 -26.038 298.122 1.00 40.66 ? 444 ASN B CA 1 ATOM 7536 C C . ASN B 1 444 ? -37.906 -24.794 297.489 1.00 38.55 ? 444 ASN B C 1 ATOM 7537 O O . ASN B 1 444 ? -37.810 -24.702 296.262 1.00 40.19 ? 444 ASN B O 1 ATOM 7538 C CB . ASN B 1 444 ? -38.533 -27.218 297.138 1.00 41.39 ? 444 ASN B CB 1 ATOM 7539 C CG . ASN B 1 444 ? -37.136 -27.655 296.703 1.00 38.51 ? 444 ASN B CG 1 ATOM 7540 O OD1 . ASN B 1 444 ? -36.208 -26.852 296.650 1.00 47.55 ? 444 ASN B OD1 1 ATOM 7541 N ND2 . ASN B 1 444 ? -36.986 -28.948 296.408 1.00 47.35 ? 444 ASN B ND2 1 ATOM 7542 N N . TYR B 1 445 ? -37.477 -23.840 298.313 1.00 38.09 ? 445 TYR B N 1 ATOM 7543 C CA . TYR B 1 445 ? -36.877 -22.615 297.807 1.00 38.88 ? 445 TYR B CA 1 ATOM 7544 C C . TYR B 1 445 ? -35.859 -22.090 298.807 1.00 40.08 ? 445 TYR B C 1 ATOM 7545 O O . TYR B 1 445 ? -36.070 -22.168 300.020 1.00 42.64 ? 445 TYR B O 1 ATOM 7546 C CB . TYR B 1 445 ? -37.936 -21.539 297.531 1.00 37.95 ? 445 TYR B CB 1 ATOM 7547 C CG . TYR B 1 445 ? -38.851 -21.250 298.701 1.00 37.86 ? 445 TYR B CG 1 ATOM 7548 C CD1 . TYR B 1 445 ? -38.537 -20.261 299.625 1.00 39.75 ? 445 TYR B CD1 1 ATOM 7549 C CD2 . TYR B 1 445 ? -40.031 -21.959 298.876 1.00 47.39 ? 445 TYR B CD2 1 ATOM 7550 C CE1 . TYR B 1 445 ? -39.370 -19.992 300.694 1.00 38.72 ? 445 TYR B CE1 1 ATOM 7551 C CE2 . TYR B 1 445 ? -40.871 -21.696 299.942 1.00 62.14 ? 445 TYR B CE2 1 ATOM 7552 C CZ . TYR B 1 445 ? -40.536 -20.712 300.847 1.00 41.46 ? 445 TYR B CZ 1 ATOM 7553 O OH . TYR B 1 445 ? -41.368 -20.448 301.910 1.00 38.79 ? 445 TYR B OH 1 ATOM 7554 N N . THR B 1 446 ? -34.754 -21.562 298.286 1.00 40.60 ? 446 THR B N 1 ATOM 7555 C CA . THR B 1 446 ? -33.789 -20.845 299.103 1.00 41.99 ? 446 THR B CA 1 ATOM 7556 C C . THR B 1 446 ? -34.221 -19.389 299.241 1.00 45.80 ? 446 THR B C 1 ATOM 7557 O O . THR B 1 446 ? -35.279 -18.982 298.751 1.00 54.43 ? 446 THR B O 1 ATOM 7558 C CB . THR B 1 446 ? -32.393 -20.931 298.490 1.00 45.89 ? 446 THR B CB 1 ATOM 7559 O OG1 . THR B 1 446 ? -32.379 -20.233 297.238 1.00 41.77 ? 446 THR B OG1 1 ATOM 7560 C CG2 . THR B 1 446 ? -31.995 -22.377 298.261 1.00 62.83 ? 446 THR B CG2 1 ATOM 7561 N N . ASN B 1 447 ? -33.392 -18.598 299.917 1.00 49.19 ? 447 ASN B N 1 ATOM 7562 C CA . ASN B 1 447 ? -33.579 -17.144 299.995 1.00 73.34 ? 447 ASN B CA 1 ATOM 7563 C C . ASN B 1 447 ? -34.958 -16.885 300.614 1.00 52.79 ? 447 ASN B C 1 ATOM 7564 O O . ASN B 1 447 ? -35.462 -17.701 301.397 1.00 50.50 ? 447 ASN B O 1 ATOM 7565 C CB . ASN B 1 447 ? -33.358 -16.549 298.603 1.00 77.73 ? 447 ASN B CB 1 ATOM 7566 C CG . ASN B 1 447 ? -33.355 -15.029 298.589 1.00 70.18 ? 447 ASN B CG 1 ATOM 7567 O OD1 . ASN B 1 447 ? -33.817 -14.382 299.528 1.00 70.10 ? 447 ASN B OD1 1 ATOM 7568 N ND2 . ASN B 1 447 ? -32.849 -14.453 297.504 1.00 58.85 ? 447 ASN B ND2 1 ATOM 7569 N N . ASP B 1 448 ? -35.574 -15.750 300.285 1.00 49.44 ? 448 ASP B N 1 ATOM 7570 C CA . ASP B 1 448 ? -36.991 -15.522 300.537 1.00 48.42 ? 448 ASP B CA 1 ATOM 7571 C C . ASP B 1 448 ? -37.729 -15.159 299.255 1.00 66.28 ? 448 ASP B C 1 ATOM 7572 O O . ASP B 1 448 ? -38.842 -14.629 299.312 1.00 79.92 ? 448 ASP B O 1 ATOM 7573 C CB . ASP B 1 448 ? -37.197 -14.445 301.603 1.00 48.16 ? 448 ASP B CB 1 ATOM 7574 C CG . ASP B 1 448 ? -37.112 -14.999 303.011 1.00 46.84 ? 448 ASP B CG 1 ATOM 7575 O OD1 . ASP B 1 448 ? -37.449 -16.187 303.202 1.00 43.87 ? 448 ASP B OD1 1 ATOM 7576 O OD2 . ASP B 1 448 ? -36.717 -14.249 303.927 1.00 55.89 ? 448 ASP B OD2 1 ATOM 7577 N N . ASN B 1 449 ? -37.123 -15.423 298.099 1.00 49.39 ? 449 ASN B N 1 ATOM 7578 C CA . ASN B 1 449 ? -37.817 -15.309 296.825 1.00 57.61 ? 449 ASN B CA 1 ATOM 7579 C C . ASN B 1 449 ? -38.468 -16.652 296.512 1.00 45.21 ? 449 ASN B C 1 ATOM 7580 O O . ASN B 1 449 ? -37.795 -17.687 296.462 1.00 44.16 ? 449 ASN B O 1 ATOM 7581 C CB . ASN B 1 449 ? -36.870 -14.856 295.709 1.00 45.06 ? 449 ASN B CB 1 ATOM 7582 C CG . ASN B 1 449 ? -35.865 -15.918 295.310 1.00 44.36 ? 449 ASN B CG 1 ATOM 7583 O OD1 . ASN B 1 449 ? -35.344 -16.647 296.151 1.00 47.85 ? 449 ASN B OD1 1 ATOM 7584 N ND2 . ASN B 1 449 ? -35.592 -16.012 294.014 1.00 40.47 ? 449 ASN B ND2 1 ATOM 7585 N N . TYR B 1 450 ? -39.783 -16.636 296.345 1.00 43.45 ? 450 TYR B N 1 ATOM 7586 C CA . TYR B 1 450 ? -40.565 -17.849 296.171 1.00 44.11 ? 450 TYR B CA 1 ATOM 7587 C C . TYR B 1 450 ? -40.716 -18.239 294.709 1.00 47.47 ? 450 TYR B C 1 ATOM 7588 O O . TYR B 1 450 ? -41.475 -19.162 294.396 1.00 69.20 ? 450 TYR B O 1 ATOM 7589 C CB . TYR B 1 450 ? -41.926 -17.666 296.840 1.00 65.59 ? 450 TYR B CB 1 ATOM 7590 C CG . TYR B 1 450 ? -41.825 -16.799 298.075 1.00 48.15 ? 450 TYR B CG 1 ATOM 7591 C CD1 . TYR B 1 450 ? -41.401 -17.333 299.285 1.00 52.19 ? 450 TYR B CD1 1 ATOM 7592 C CD2 . TYR B 1 450 ? -42.118 -15.442 298.025 1.00 47.26 ? 450 TYR B CD2 1 ATOM 7593 C CE1 . TYR B 1 450 ? -41.291 -16.545 300.414 1.00 50.43 ? 450 TYR B CE1 1 ATOM 7594 C CE2 . TYR B 1 450 ? -42.009 -14.646 299.150 1.00 47.14 ? 450 TYR B CE2 1 ATOM 7595 C CZ . TYR B 1 450 ? -41.599 -15.204 300.342 1.00 50.54 ? 450 TYR B CZ 1 ATOM 7596 O OH . TYR B 1 450 ? -41.489 -14.417 301.465 1.00 44.59 ? 450 TYR B OH 1 ATOM 7597 N N . PHE B 1 451 ? -40.007 -17.557 293.813 1.00 37.40 ? 451 PHE B N 1 ATOM 7598 C CA . PHE B 1 451 ? -39.924 -17.950 292.416 1.00 37.89 ? 451 PHE B CA 1 ATOM 7599 C C . PHE B 1 451 ? -38.799 -18.942 292.158 1.00 41.91 ? 451 PHE B C 1 ATOM 7600 O O . PHE B 1 451 ? -38.772 -19.564 291.090 1.00 39.70 ? 451 PHE B O 1 ATOM 7601 C CB . PHE B 1 451 ? -39.744 -16.710 291.538 1.00 33.56 ? 451 PHE B CB 1 ATOM 7602 C CG . PHE B 1 451 ? -40.758 -15.637 291.803 1.00 35.37 ? 451 PHE B CG 1 ATOM 7603 C CD1 . PHE B 1 451 ? -42.019 -15.706 291.237 1.00 35.35 ? 451 PHE B CD1 1 ATOM 7604 C CD2 . PHE B 1 451 ? -40.460 -14.571 292.635 1.00 33.21 ? 451 PHE B CD2 1 ATOM 7605 C CE1 . PHE B 1 451 ? -42.958 -14.725 291.480 1.00 32.75 ? 451 PHE B CE1 1 ATOM 7606 C CE2 . PHE B 1 451 ? -41.397 -13.588 292.885 1.00 35.76 ? 451 PHE B CE2 1 ATOM 7607 C CZ . PHE B 1 451 ? -42.649 -13.666 292.307 1.00 35.32 ? 451 PHE B CZ 1 ATOM 7608 N N . SER B 1 452 ? -37.876 -19.099 293.107 1.00 44.35 ? 452 SER B N 1 ATOM 7609 C CA . SER B 1 452 ? -36.888 -20.166 293.056 1.00 41.16 ? 452 SER B CA 1 ATOM 7610 C C . SER B 1 452 ? -37.475 -21.518 293.429 1.00 39.72 ? 452 SER B C 1 ATOM 7611 O O . SER B 1 452 ? -36.838 -22.546 293.175 1.00 38.43 ? 452 SER B O 1 ATOM 7612 C CB . SER B 1 452 ? -35.719 -19.845 293.992 1.00 41.07 ? 452 SER B CB 1 ATOM 7613 O OG . SER B 1 452 ? -36.176 -19.611 295.315 1.00 40.75 ? 452 SER B OG 1 ATOM 7614 N N . GLY B 1 453 ? -38.665 -21.541 294.017 1.00 39.53 ? 453 GLY B N 1 ATOM 7615 C CA . GLY B 1 453 ? -39.279 -22.762 294.489 1.00 38.34 ? 453 GLY B CA 1 ATOM 7616 C C . GLY B 1 453 ? -40.104 -23.463 293.436 1.00 44.11 ? 453 GLY B C 1 ATOM 7617 O O . GLY B 1 453 ? -39.887 -23.320 292.230 1.00 50.20 ? 453 GLY B O 1 ATOM 7618 N N . THR B 1 454 ? -41.071 -24.242 293.913 1.00 45.30 ? 454 THR B N 1 ATOM 7619 C CA . THR B 1 454 ? -41.964 -24.998 293.049 1.00 43.96 ? 454 THR B CA 1 ATOM 7620 C C . THR B 1 454 ? -43.343 -25.039 293.683 1.00 37.56 ? 454 THR B C 1 ATOM 7621 O O . THR B 1 454 ? -43.486 -25.455 294.836 1.00 37.57 ? 454 THR B O 1 ATOM 7622 C CB . THR B 1 454 ? -41.448 -26.422 292.821 1.00 38.80 ? 454 THR B CB 1 ATOM 7623 O OG1 . THR B 1 454 ? -40.105 -26.372 292.325 1.00 38.23 ? 454 THR B OG1 1 ATOM 7624 C CG2 . THR B 1 454 ? -42.328 -27.150 291.817 1.00 46.82 ? 454 THR B CG2 1 ATOM 7625 N N . GLY B 1 455 ? -44.351 -24.598 292.934 1.00 37.66 ? 455 GLY B N 1 ATOM 7626 C CA . GLY B 1 455 ? -45.709 -24.677 293.417 1.00 52.04 ? 455 GLY B CA 1 ATOM 7627 C C . GLY B 1 455 ? -46.300 -26.062 293.249 1.00 41.77 ? 455 GLY B C 1 ATOM 7628 O O . GLY B 1 455 ? -45.780 -26.912 292.528 1.00 41.12 ? 455 GLY B O 1 ATOM 7629 N N . ASN B 1 456 ? -47.411 -26.293 293.943 1.00 45.09 ? 456 ASN B N 1 ATOM 7630 C CA . ASN B 1 456 ? -48.107 -27.567 293.832 1.00 51.15 ? 456 ASN B CA 1 ATOM 7631 C C . ASN B 1 456 ? -49.550 -27.327 293.411 1.00 48.99 ? 456 ASN B C 1 ATOM 7632 O O . ASN B 1 456 ? -50.485 -27.688 294.133 1.00 51.18 ? 456 ASN B O 1 ATOM 7633 C CB . ASN B 1 456 ? -48.043 -28.335 295.155 1.00 58.59 ? 456 ASN B CB 1 ATOM 7634 C CG . ASN B 1 456 ? -48.431 -29.796 295.004 1.00 92.14 ? 456 ASN B CG 1 ATOM 7635 O OD1 . ASN B 1 456 ? -49.051 -30.190 294.017 1.00 75.54 ? 456 ASN B OD1 1 ATOM 7636 N ND2 . ASN B 1 456 ? -48.063 -30.608 295.988 1.00 136.60 ? 456 ASN B ND2 1 ATOM 7637 N N . GLY B 1 457 ? -49.738 -26.712 292.246 1.00 46.61 ? 457 GLY B N 1 ATOM 7638 C CA . GLY B 1 457 ? -51.057 -26.420 291.743 1.00 52.11 ? 457 GLY B CA 1 ATOM 7639 C C . GLY B 1 457 ? -51.331 -24.932 291.671 1.00 40.07 ? 457 GLY B C 1 ATOM 7640 O O . GLY B 1 457 ? -50.571 -24.110 292.191 1.00 41.42 ? 457 GLY B O 1 ATOM 7641 N N . PRO B 1 458 ? -52.426 -24.558 291.017 1.00 37.91 ? 458 PRO B N 1 ATOM 7642 C CA . PRO B 1 458 ? -52.780 -23.141 290.915 1.00 38.08 ? 458 PRO B CA 1 ATOM 7643 C C . PRO B 1 458 ? -53.393 -22.613 292.201 1.00 33.14 ? 458 PRO B C 1 ATOM 7644 O O . PRO B 1 458 ? -54.063 -23.331 292.945 1.00 31.88 ? 458 PRO B O 1 ATOM 7645 C CB . PRO B 1 458 ? -53.802 -23.119 289.772 1.00 34.62 ? 458 PRO B CB 1 ATOM 7646 C CG . PRO B 1 458 ? -54.440 -24.462 289.834 1.00 37.72 ? 458 PRO B CG 1 ATOM 7647 C CD . PRO B 1 458 ? -53.359 -25.419 290.269 1.00 59.80 ? 458 PRO B CD 1 ATOM 7648 N N . VAL B 1 459 ? -53.151 -21.325 292.452 1.00 33.88 ? 459 VAL B N 1 ATOM 7649 C CA . VAL B 1 459 ? -53.729 -20.675 293.620 1.00 33.14 ? 459 VAL B CA 1 ATOM 7650 C C . VAL B 1 459 ? -55.241 -20.582 293.452 1.00 34.82 ? 459 VAL B C 1 ATOM 7651 O O . VAL B 1 459 ? -55.769 -20.566 292.331 1.00 33.93 ? 459 VAL B O 1 ATOM 7652 C CB . VAL B 1 459 ? -53.101 -19.284 293.834 1.00 33.15 ? 459 VAL B CB 1 ATOM 7653 C CG1 . VAL B 1 459 ? -53.629 -18.291 292.807 1.00 29.60 ? 459 VAL B CG1 1 ATOM 7654 C CG2 . VAL B 1 459 ? -53.346 -18.788 295.254 1.00 32.93 ? 459 VAL B CG2 1 ATOM 7655 N N . SER B 1 460 ? -55.950 -20.541 294.577 1.00 37.54 ? 460 SER B N 1 ATOM 7656 C CA . SER B 1 460 ? -57.402 -20.416 294.550 1.00 42.30 ? 460 SER B CA 1 ATOM 7657 C C . SER B 1 460 ? -57.788 -19.057 293.978 1.00 34.20 ? 460 SER B C 1 ATOM 7658 O O . SER B 1 460 ? -57.501 -18.017 294.580 1.00 36.92 ? 460 SER B O 1 ATOM 7659 C CB . SER B 1 460 ? -57.975 -20.595 295.953 1.00 60.64 ? 460 SER B CB 1 ATOM 7660 O OG . SER B 1 460 ? -57.373 -21.697 296.610 1.00 66.77 ? 460 SER B OG 1 ATOM 7661 N N . GLY B 1 461 ? -58.436 -19.066 292.812 1.00 33.94 ? 461 GLY B N 1 ATOM 7662 C CA . GLY B 1 461 ? -58.800 -17.850 292.123 1.00 33.06 ? 461 GLY B CA 1 ATOM 7663 C C . GLY B 1 461 ? -60.255 -17.460 292.340 1.00 34.72 ? 461 GLY B C 1 ATOM 7664 O O . GLY B 1 461 ? -61.043 -18.165 292.966 1.00 50.23 ? 461 GLY B O 1 ATOM 7665 N N . THR B 1 462 ? -60.601 -16.293 291.797 1.00 33.94 ? 462 THR B N 1 ATOM 7666 C CA . THR B 1 462 ? -61.959 -15.777 291.901 1.00 33.19 ? 462 THR B CA 1 ATOM 7667 C C . THR B 1 462 ? -62.901 -16.582 291.018 1.00 31.44 ? 462 THR B C 1 ATOM 7668 O O . THR B 1 462 ? -63.767 -17.307 291.517 1.00 36.96 ? 462 THR B O 1 ATOM 7669 C CB . THR B 1 462 ? -62.011 -14.300 291.506 1.00 33.45 ? 462 THR B CB 1 ATOM 7670 O OG1 . THR B 1 462 ? -60.937 -13.594 292.139 1.00 32.40 ? 462 THR B OG1 1 ATOM 7671 C CG2 . THR B 1 462 ? -63.332 -13.686 291.940 1.00 53.16 ? 462 THR B CG2 1 ATOM 7672 N N . TRP B 1 463 ? -62.736 -16.460 289.702 1.00 32.57 ? 463 TRP B N 1 ATOM 7673 C CA . TRP B 1 463 ? -63.573 -17.158 288.736 1.00 34.72 ? 463 TRP B CA 1 ATOM 7674 C C . TRP B 1 463 ? -62.876 -18.375 288.142 1.00 34.61 ? 463 TRP B C 1 ATOM 7675 O O . TRP B 1 463 ? -63.478 -19.447 288.035 1.00 30.17 ? 463 TRP B O 1 ATOM 7676 C CB . TRP B 1 463 ? -63.992 -16.195 287.619 1.00 34.68 ? 463 TRP B CB 1 ATOM 7677 C CG . TRP B 1 463 ? -64.280 -14.814 288.116 1.00 31.45 ? 463 TRP B CG 1 ATOM 7678 C CD1 . TRP B 1 463 ? -63.511 -13.702 287.936 1.00 38.05 ? 463 TRP B CD1 1 ATOM 7679 C CD2 . TRP B 1 463 ? -65.408 -14.399 288.896 1.00 32.38 ? 463 TRP B CD2 1 ATOM 7680 N NE1 . TRP B 1 463 ? -64.094 -12.618 288.545 1.00 32.51 ? 463 TRP B NE1 1 ATOM 7681 C CE2 . TRP B 1 463 ? -65.259 -13.020 289.143 1.00 30.64 ? 463 TRP B CE2 1 ATOM 7682 C CE3 . TRP B 1 463 ? -66.530 -15.058 289.406 1.00 45.45 ? 463 TRP B CE3 1 ATOM 7683 C CZ2 . TRP B 1 463 ? -66.190 -12.288 289.876 1.00 31.49 ? 463 TRP B CZ2 1 ATOM 7684 C CZ3 . TRP B 1 463 ? -67.454 -14.330 290.133 1.00 56.91 ? 463 TRP B CZ3 1 ATOM 7685 C CH2 . TRP B 1 463 ? -67.278 -12.960 290.362 1.00 34.90 ? 463 TRP B CH2 1 ATOM 7686 N N . GLU B 1 464 ? -61.611 -18.229 287.758 1.00 34.95 ? 464 GLU B N 1 ATOM 7687 C CA . GLU B 1 464 ? -60.818 -19.311 287.195 1.00 33.29 ? 464 GLU B CA 1 ATOM 7688 C C . GLU B 1 464 ? -59.611 -19.566 288.085 1.00 31.78 ? 464 GLU B C 1 ATOM 7689 O O . GLU B 1 464 ? -59.002 -18.624 288.603 1.00 42.14 ? 464 GLU B O 1 ATOM 7690 C CB . GLU B 1 464 ? -60.367 -18.976 285.767 1.00 34.88 ? 464 GLU B CB 1 ATOM 7691 C CG . GLU B 1 464 ? -59.148 -19.749 285.290 1.00 38.82 ? 464 GLU B CG 1 ATOM 7692 C CD . GLU B 1 464 ? -58.807 -19.470 283.840 1.00 48.67 ? 464 GLU B CD 1 ATOM 7693 O OE1 . GLU B 1 464 ? -59.720 -19.099 283.072 1.00 46.43 ? 464 GLU B OE1 1 ATOM 7694 O OE2 . GLU B 1 464 ? -57.624 -19.621 283.468 1.00 50.26 ? 464 GLU B OE2 1 ATOM 7695 N N . ASP B 1 465 ? -59.276 -20.841 288.270 1.00 34.02 ? 465 ASP B N 1 ATOM 7696 C CA . ASP B 1 465 ? -58.110 -21.198 289.065 1.00 35.09 ? 465 ASP B CA 1 ATOM 7697 C C . ASP B 1 465 ? -56.836 -20.687 288.403 1.00 33.13 ? 465 ASP B C 1 ATOM 7698 O O . ASP B 1 465 ? -56.693 -20.721 287.178 1.00 29.94 ? 465 ASP B O 1 ATOM 7699 C CB . ASP B 1 465 ? -58.036 -22.714 289.251 1.00 35.05 ? 465 ASP B CB 1 ATOM 7700 C CG . ASP B 1 465 ? -58.925 -23.205 290.374 1.00 39.15 ? 465 ASP B CG 1 ATOM 7701 O OD1 . ASP B 1 465 ? -59.680 -22.386 290.936 1.00 39.42 ? 465 ASP B OD1 1 ATOM 7702 O OD2 . ASP B 1 465 ? -58.867 -24.411 290.695 1.00 45.89 ? 465 ASP B OD2 1 ATOM 7703 N N . GLY B 1 466 ? -55.905 -20.210 289.227 1.00 36.26 ? 466 GLY B N 1 ATOM 7704 C CA . GLY B 1 466 ? -54.665 -19.649 288.741 1.00 45.04 ? 466 GLY B CA 1 ATOM 7705 C C . GLY B 1 466 ? -54.718 -18.174 288.410 1.00 33.38 ? 466 GLY B C 1 ATOM 7706 O O . GLY B 1 466 ? -53.673 -17.591 288.095 1.00 31.64 ? 466 GLY B O 1 ATOM 7707 N N . VAL B 1 467 ? -55.895 -17.554 288.461 1.00 29.35 ? 467 VAL B N 1 ATOM 7708 C CA . VAL B 1 467 ? -56.063 -16.131 288.193 1.00 28.97 ? 467 VAL B CA 1 ATOM 7709 C C . VAL B 1 467 ? -56.938 -15.541 289.289 1.00 28.35 ? 467 VAL B C 1 ATOM 7710 O O . VAL B 1 467 ? -58.013 -16.075 289.585 1.00 29.73 ? 467 VAL B O 1 ATOM 7711 C CB . VAL B 1 467 ? -56.691 -15.872 286.810 1.00 33.11 ? 467 VAL B CB 1 ATOM 7712 C CG1 . VAL B 1 467 ? -56.890 -14.379 286.589 1.00 25.93 ? 467 VAL B CG1 1 ATOM 7713 C CG2 . VAL B 1 467 ? -55.828 -16.466 285.708 1.00 36.61 ? 467 VAL B CG2 1 ATOM 7714 N N . VAL B 1 468 ? -56.482 -14.443 289.886 1.00 25.24 ? 468 VAL B N 1 ATOM 7715 C CA . VAL B 1 468 ? -57.206 -13.759 290.950 1.00 27.16 ? 468 VAL B CA 1 ATOM 7716 C C . VAL B 1 468 ? -57.416 -12.312 290.532 1.00 26.71 ? 468 VAL B C 1 ATOM 7717 O O . VAL B 1 468 ? -56.471 -11.646 290.092 1.00 24.65 ? 468 VAL B O 1 ATOM 7718 C CB . VAL B 1 468 ? -56.456 -13.835 292.292 1.00 29.31 ? 468 VAL B CB 1 ATOM 7719 C CG1 . VAL B 1 468 ? -57.205 -13.060 293.365 1.00 28.92 ? 468 VAL B CG1 1 ATOM 7720 C CG2 . VAL B 1 468 ? -56.263 -15.283 292.711 1.00 35.88 ? 468 VAL B CG2 1 ATOM 7721 N N . ASP B 1 469 ? -58.650 -11.831 290.661 1.00 26.89 ? 469 ASP B N 1 ATOM 7722 C CA . ASP B 1 469 ? -58.937 -10.434 290.371 1.00 27.12 ? 469 ASP B CA 1 ATOM 7723 C C . ASP B 1 469 ? -58.168 -9.531 291.328 1.00 26.07 ? 469 ASP B C 1 ATOM 7724 O O . ASP B 1 469 ? -57.948 -9.868 292.494 1.00 28.74 ? 469 ASP B O 1 ATOM 7725 C CB . ASP B 1 469 ? -60.437 -10.157 290.487 1.00 27.65 ? 469 ASP B CB 1 ATOM 7726 C CG . ASP B 1 469 ? -61.246 -10.848 289.408 1.00 35.97 ? 469 ASP B CG 1 ATOM 7727 O OD1 . ASP B 1 469 ? -60.885 -10.726 288.219 1.00 45.69 ? 469 ASP B OD1 1 ATOM 7728 O OD2 . ASP B 1 469 ? -62.250 -11.507 289.749 1.00 31.92 ? 469 ASP B OD2 1 ATOM 7729 N N . TYR B 1 470 ? -57.752 -8.367 290.820 1.00 24.08 ? 470 TYR B N 1 ATOM 7730 C CA . TYR B 1 470 ? -57.039 -7.415 291.665 1.00 26.84 ? 470 TYR B CA 1 ATOM 7731 C C . TYR B 1 470 ? -57.900 -6.951 292.831 1.00 28.48 ? 470 TYR B C 1 ATOM 7732 O O . TYR B 1 470 ? -57.377 -6.675 293.917 1.00 39.63 ? 470 TYR B O 1 ATOM 7733 C CB . TYR B 1 470 ? -56.580 -6.211 290.842 1.00 30.36 ? 470 TYR B CB 1 ATOM 7734 C CG . TYR B 1 470 ? -56.043 -5.076 291.684 1.00 28.36 ? 470 TYR B CG 1 ATOM 7735 C CD1 . TYR B 1 470 ? -54.738 -5.095 292.153 1.00 25.68 ? 470 TYR B CD1 1 ATOM 7736 C CD2 . TYR B 1 470 ? -56.844 -3.991 292.019 1.00 28.02 ? 470 TYR B CD2 1 ATOM 7737 C CE1 . TYR B 1 470 ? -54.243 -4.066 292.925 1.00 29.00 ? 470 TYR B CE1 1 ATOM 7738 C CE2 . TYR B 1 470 ? -56.358 -2.958 292.795 1.00 26.43 ? 470 TYR B CE2 1 ATOM 7739 C CZ . TYR B 1 470 ? -55.056 -3.000 293.245 1.00 29.37 ? 470 TYR B CZ 1 ATOM 7740 O OH . TYR B 1 470 ? -54.562 -1.974 294.016 1.00 38.00 ? 470 TYR B OH 1 ATOM 7741 N N . ARG B 1 471 ? -59.215 -6.856 292.625 1.00 25.51 ? 471 ARG B N 1 ATOM 7742 C CA . ARG B 1 471 ? -60.103 -6.412 293.694 1.00 26.78 ? 471 ARG B CA 1 ATOM 7743 C C . ARG B 1 471 ? -60.050 -7.360 294.885 1.00 31.32 ? 471 ARG B C 1 ATOM 7744 O O . ARG B 1 471 ? -60.069 -6.920 296.040 1.00 40.11 ? 471 ARG B O 1 ATOM 7745 C CB . ARG B 1 471 ? -61.533 -6.286 293.168 1.00 30.15 ? 471 ARG B CB 1 ATOM 7746 C CG . ARG B 1 471 ? -62.570 -6.028 294.249 1.00 27.42 ? 471 ARG B CG 1 ATOM 7747 C CD . ARG B 1 471 ? -63.862 -5.460 293.681 1.00 24.13 ? 471 ARG B CD 1 ATOM 7748 N NE . ARG B 1 471 ? -64.299 -6.161 292.478 1.00 25.14 ? 471 ARG B NE 1 ATOM 7749 C CZ . ARG B 1 471 ? -64.627 -5.558 291.341 1.00 27.50 ? 471 ARG B CZ 1 ATOM 7750 N NH1 . ARG B 1 471 ? -64.570 -4.236 291.249 1.00 24.50 ? 471 ARG B NH1 1 ATOM 7751 N NH2 . ARG B 1 471 ? -65.015 -6.275 290.295 1.00 38.97 ? 471 ARG B NH2 1 ATOM 7752 N N . GLN B 1 472 ? -59.970 -8.665 294.624 1.00 29.27 ? 472 GLN B N 1 ATOM 7753 C CA . GLN B 1 472 ? -59.922 -9.635 295.711 1.00 32.44 ? 472 GLN B CA 1 ATOM 7754 C C . GLN B 1 472 ? -58.555 -9.670 296.383 1.00 33.27 ? 472 GLN B C 1 ATOM 7755 O O . GLN B 1 472 ? -58.470 -9.936 297.588 1.00 57.73 ? 472 GLN B O 1 ATOM 7756 C CB . GLN B 1 472 ? -60.307 -11.024 295.187 1.00 36.66 ? 472 GLN B CB 1 ATOM 7757 C CG . GLN B 1 472 ? -59.902 -12.182 296.084 1.00 39.38 ? 472 GLN B CG 1 ATOM 7758 C CD . GLN B 1 472 ? -60.107 -13.531 295.425 1.00 52.23 ? 472 GLN B CD 1 ATOM 7759 O OE1 . GLN B 1 472 ? -60.324 -13.618 294.218 1.00 52.59 ? 472 GLN B OE1 1 ATOM 7760 N NE2 . GLN B 1 472 ? -60.044 -14.594 296.219 1.00 50.94 ? 472 GLN B NE2 1 ATOM 7761 N N . ILE B 1 473 ? -57.484 -9.392 295.633 1.00 28.04 ? 473 ILE B N 1 ATOM 7762 C CA . ILE B 1 473 ? -56.146 -9.361 296.221 1.00 25.17 ? 473 ILE B CA 1 ATOM 7763 C C . ILE B 1 473 ? -56.076 -8.325 297.335 1.00 30.21 ? 473 ILE B C 1 ATOM 7764 O O . ILE B 1 473 ? -55.479 -8.566 298.392 1.00 33.89 ? 473 ILE B O 1 ATOM 7765 C CB . ILE B 1 473 ? -55.089 -9.091 295.134 1.00 21.50 ? 473 ILE B CB 1 ATOM 7766 C CG1 . ILE B 1 473 ? -55.045 -10.241 294.129 1.00 24.07 ? 473 ILE B CG1 1 ATOM 7767 C CG2 . ILE B 1 473 ? -53.718 -8.883 295.759 1.00 24.07 ? 473 ILE B CG2 1 ATOM 7768 C CD1 . ILE B 1 473 ? -53.999 -10.066 293.053 1.00 25.31 ? 473 ILE B CD1 1 ATOM 7769 N N . GLN B 1 474 ? -56.692 -7.159 297.122 1.00 31.13 ? 474 GLN B N 1 ATOM 7770 C CA . GLN B 1 474 ? -56.671 -6.108 298.135 1.00 31.07 ? 474 GLN B CA 1 ATOM 7771 C C . GLN B 1 474 ? -57.399 -6.526 299.405 1.00 34.42 ? 474 GLN B C 1 ATOM 7772 O O . GLN B 1 474 ? -57.077 -6.035 300.493 1.00 37.54 ? 474 GLN B O 1 ATOM 7773 C CB . GLN B 1 474 ? -57.289 -4.829 297.573 1.00 29.78 ? 474 GLN B CB 1 ATOM 7774 C CG . GLN B 1 474 ? -56.564 -4.269 296.366 1.00 36.09 ? 474 GLN B CG 1 ATOM 7775 C CD . GLN B 1 474 ? -55.156 -3.821 296.696 1.00 32.14 ? 474 GLN B CD 1 ATOM 7776 O OE1 . GLN B 1 474 ? -54.201 -4.177 296.008 1.00 35.95 ? 474 GLN B OE1 1 ATOM 7777 N NE2 . GLN B 1 474 ? -55.021 -3.028 297.752 1.00 42.70 ? 474 GLN B NE2 1 ATOM 7778 N N . LYS B 1 475 ? -58.379 -7.424 299.293 1.00 36.04 ? 475 LYS B N 1 ATOM 7779 C CA . LYS B 1 475 ? -59.158 -7.821 300.463 1.00 42.09 ? 475 LYS B CA 1 ATOM 7780 C C . LYS B 1 475 ? -58.409 -8.836 301.320 1.00 40.97 ? 475 LYS B C 1 ATOM 7781 O O . LYS B 1 475 ? -58.476 -8.779 302.553 1.00 60.09 ? 475 LYS B O 1 ATOM 7782 C CB . LYS B 1 475 ? -60.519 -8.376 300.031 1.00 42.99 ? 475 LYS B CB 1 ATOM 7783 C CG . LYS B 1 475 ? -61.282 -7.522 299.011 1.00 50.16 ? 475 LYS B CG 1 ATOM 7784 C CD . LYS B 1 475 ? -61.075 -6.019 299.222 1.00 80.83 ? 475 LYS B CD 1 ATOM 7785 C CE . LYS B 1 475 ? -62.230 -5.212 298.661 1.00 66.25 ? 475 LYS B CE 1 ATOM 7786 N NZ . LYS B 1 475 ? -62.815 -5.856 297.459 1.00 75.94 ? 475 LYS B NZ 1 ATOM 7787 N N . ASP B 1 476 ? -57.696 -9.769 300.690 1.00 37.99 ? 476 ASP B N 1 ATOM 7788 C CA . ASP B 1 476 ? -56.861 -10.728 301.399 1.00 41.69 ? 476 ASP B CA 1 ATOM 7789 C C . ASP B 1 476 ? -55.447 -10.207 301.630 1.00 36.95 ? 476 ASP B C 1 ATOM 7790 O O . ASP B 1 476 ? -54.543 -11.001 301.911 1.00 43.60 ? 476 ASP B O 1 ATOM 7791 C CB . ASP B 1 476 ? -56.809 -12.052 300.633 1.00 60.71 ? 476 ASP B CB 1 ATOM 7792 C CG . ASP B 1 476 ? -58.185 -12.621 300.354 1.00 47.73 ? 476 ASP B CG 1 ATOM 7793 O OD1 . ASP B 1 476 ? -59.128 -12.303 301.108 1.00 45.85 ? 476 ASP B OD1 1 ATOM 7794 O OD2 . ASP B 1 476 ? -58.323 -13.392 299.380 1.00 36.01 ? 476 ASP B OD2 1 ATOM 7795 N N . LEU B 1 477 ? -55.243 -8.891 301.528 1.00 35.59 ? 477 LEU B N 1 ATOM 7796 C CA . LEU B 1 477 ? -53.889 -8.345 301.529 1.00 36.15 ? 477 LEU B CA 1 ATOM 7797 C C . LEU B 1 477 ? -53.174 -8.613 302.847 1.00 52.06 ? 477 LEU B C 1 ATOM 7798 O O . LEU B 1 477 ? -51.964 -8.868 302.862 1.00 47.21 ? 477 LEU B O 1 ATOM 7799 C CB . LEU B 1 477 ? -53.930 -6.846 301.237 1.00 35.26 ? 477 LEU B CB 1 ATOM 7800 C CG . LEU B 1 477 ? -52.578 -6.143 301.101 1.00 31.98 ? 477 LEU B CG 1 ATOM 7801 C CD1 . LEU B 1 477 ? -51.677 -6.903 300.141 1.00 38.92 ? 477 LEU B CD1 1 ATOM 7802 C CD2 . LEU B 1 477 ? -52.765 -4.706 300.641 1.00 30.83 ? 477 LEU B CD2 1 ATOM 7803 N N . ASN B 1 478 ? -53.898 -8.562 303.964 1.00 39.47 ? 478 ASN B N 1 ATOM 7804 C CA . ASN B 1 478 ? -53.281 -8.837 305.255 1.00 42.29 ? 478 ASN B CA 1 ATOM 7805 C C . ASN B 1 478 ? -53.005 -10.325 305.452 1.00 39.40 ? 478 ASN B C 1 ATOM 7806 O O . ASN B 1 478 ? -52.212 -10.685 306.328 1.00 44.16 ? 478 ASN B O 1 ATOM 7807 C CB . ASN B 1 478 ? -54.166 -8.269 306.376 1.00 52.87 ? 478 ASN B CB 1 ATOM 7808 C CG . ASN B 1 478 ? -53.942 -8.942 307.718 1.00 84.03 ? 478 ASN B CG 1 ATOM 7809 O OD1 . ASN B 1 478 ? -54.587 -9.938 308.043 1.00 102.55 ? 478 ASN B OD1 1 ATOM 7810 N ND2 . ASN B 1 478 ? -53.018 -8.399 308.504 1.00 82.93 ? 478 ASN B ND2 1 ATOM 7811 N N . ASN B 1 479 ? -53.612 -11.193 304.638 1.00 35.67 ? 479 ASN B N 1 ATOM 7812 C CA . ASN B 1 479 ? -53.211 -12.592 304.602 1.00 35.09 ? 479 ASN B CA 1 ATOM 7813 C C . ASN B 1 479 ? -51.884 -12.796 303.886 1.00 33.61 ? 479 ASN B C 1 ATOM 7814 O O . ASN B 1 479 ? -51.266 -13.853 304.047 1.00 45.54 ? 479 ASN B O 1 ATOM 7815 C CB . ASN B 1 479 ? -54.287 -13.447 303.924 1.00 34.74 ? 479 ASN B CB 1 ATOM 7816 C CG . ASN B 1 479 ? -55.617 -13.395 304.645 1.00 35.57 ? 479 ASN B CG 1 ATOM 7817 O OD1 . ASN B 1 479 ? -55.671 -13.167 305.853 1.00 40.82 ? 479 ASN B OD1 1 ATOM 7818 N ND2 . ASN B 1 479 ? -56.700 -13.606 303.907 1.00 38.50 ? 479 ASN B ND2 1 ATOM 7819 N N . TYR B 1 480 ? -51.435 -11.821 303.103 1.00 33.31 ? 480 TYR B N 1 ATOM 7820 C CA . TYR B 1 480 ? -50.191 -11.915 302.354 1.00 30.55 ? 480 TYR B CA 1 ATOM 7821 C C . TYR B 1 480 ? -49.175 -10.906 302.874 1.00 27.87 ? 480 TYR B C 1 ATOM 7822 O O . TYR B 1 480 ? -49.480 -10.039 303.697 1.00 28.62 ? 480 TYR B O 1 ATOM 7823 C CB . TYR B 1 480 ? -50.427 -11.682 300.857 1.00 30.04 ? 480 TYR B CB 1 ATOM 7824 C CG . TYR B 1 480 ? -51.447 -12.592 300.212 1.00 31.77 ? 480 TYR B CG 1 ATOM 7825 C CD1 . TYR B 1 480 ? -51.152 -13.921 299.948 1.00 31.16 ? 480 TYR B CD1 1 ATOM 7826 C CD2 . TYR B 1 480 ? -52.693 -12.112 299.837 1.00 33.53 ? 480 TYR B CD2 1 ATOM 7827 C CE1 . TYR B 1 480 ? -52.079 -14.754 299.350 1.00 43.60 ? 480 TYR B CE1 1 ATOM 7828 C CE2 . TYR B 1 480 ? -53.627 -12.936 299.240 1.00 33.02 ? 480 TYR B CE2 1 ATOM 7829 C CZ . TYR B 1 480 ? -53.315 -14.255 298.998 1.00 37.48 ? 480 TYR B CZ 1 ATOM 7830 O OH . TYR B 1 480 ? -54.244 -15.076 298.401 1.00 38.56 ? 480 TYR B OH 1 ATOM 7831 N N . VAL B 1 481 ? -47.951 -11.033 302.369 1.00 25.39 ? 481 VAL B N 1 ATOM 7832 C CA . VAL B 1 481 ? -46.871 -10.089 302.633 1.00 23.81 ? 481 VAL B CA 1 ATOM 7833 C C . VAL B 1 481 ? -46.484 -9.454 301.306 1.00 24.25 ? 481 VAL B C 1 ATOM 7834 O O . VAL B 1 481 ? -46.044 -10.152 300.384 1.00 24.45 ? 481 VAL B O 1 ATOM 7835 C CB . VAL B 1 481 ? -45.660 -10.767 303.292 1.00 23.16 ? 481 VAL B CB 1 ATOM 7836 C CG1 . VAL B 1 481 ? -44.452 -9.844 303.251 1.00 24.40 ? 481 VAL B CG1 1 ATOM 7837 C CG2 . VAL B 1 481 ? -45.986 -11.159 304.723 1.00 25.91 ? 481 VAL B CG2 1 ATOM 7838 N N . TYR B 1 482 ? -46.651 -8.140 301.209 1.00 27.67 ? 482 TYR B N 1 ATOM 7839 C CA . TYR B 1 482 ? -46.370 -7.432 299.970 1.00 28.44 ? 482 TYR B CA 1 ATOM 7840 C C . TYR B 1 482 ? -44.868 -7.271 299.772 1.00 29.97 ? 482 TYR B C 1 ATOM 7841 O O . TYR B 1 482 ? -44.100 -7.152 300.731 1.00 28.11 ? 482 TYR B O 1 ATOM 7842 C CB . TYR B 1 482 ? -47.050 -6.062 299.971 1.00 29.17 ? 482 TYR B CB 1 ATOM 7843 C CG . TYR B 1 482 ? -46.813 -5.250 298.717 1.00 28.70 ? 482 TYR B CG 1 ATOM 7844 C CD1 . TYR B 1 482 ? -47.549 -5.489 297.564 1.00 28.03 ? 482 TYR B CD1 1 ATOM 7845 C CD2 . TYR B 1 482 ? -45.861 -4.240 298.688 1.00 27.96 ? 482 TYR B CD2 1 ATOM 7846 C CE1 . TYR B 1 482 ? -47.339 -4.750 296.416 1.00 25.22 ? 482 TYR B CE1 1 ATOM 7847 C CE2 . TYR B 1 482 ? -45.644 -3.495 297.544 1.00 25.34 ? 482 TYR B CE2 1 ATOM 7848 C CZ . TYR B 1 482 ? -46.385 -3.754 296.412 1.00 26.68 ? 482 TYR B CZ 1 ATOM 7849 O OH . TYR B 1 482 ? -46.174 -3.015 295.271 1.00 27.47 ? 482 TYR B OH 1 ATOM 7850 N N . THR B 1 483 ? -44.453 -7.275 298.507 1.00 31.91 ? 483 THR B N 1 ATOM 7851 C CA . THR B 1 483 ? -43.052 -7.091 298.152 1.00 31.37 ? 483 THR B CA 1 ATOM 7852 C C . THR B 1 483 ? -42.977 -6.434 296.783 1.00 30.55 ? 483 THR B C 1 ATOM 7853 O O . THR B 1 483 ? -43.552 -6.944 295.818 1.00 28.92 ? 483 THR B O 1 ATOM 7854 C CB . THR B 1 483 ? -42.295 -8.424 298.141 1.00 28.41 ? 483 THR B CB 1 ATOM 7855 O OG1 . THR B 1 483 ? -42.421 -9.060 299.418 1.00 27.98 ? 483 THR B OG1 1 ATOM 7856 C CG2 . THR B 1 483 ? -40.823 -8.193 297.839 1.00 30.92 ? 483 THR B CG2 1 ATOM 7857 N N . PHE B 1 484 ? -42.272 -5.309 296.706 1.00 29.38 ? 484 PHE B N 1 ATOM 7858 C CA . PHE B 1 484 ? -42.119 -4.557 295.469 1.00 30.08 ? 484 PHE B CA 1 ATOM 7859 C C . PHE B 1 484 ? -40.691 -4.698 294.963 1.00 30.10 ? 484 PHE B C 1 ATOM 7860 O O . PHE B 1 484 ? -39.736 -4.445 295.705 1.00 43.41 ? 484 PHE B O 1 ATOM 7861 C CB . PHE B 1 484 ? -42.464 -3.081 295.677 1.00 27.37 ? 484 PHE B CB 1 ATOM 7862 C CG . PHE B 1 484 ? -42.311 -2.242 294.439 1.00 26.52 ? 484 PHE B CG 1 ATOM 7863 C CD1 . PHE B 1 484 ? -43.086 -2.489 293.319 1.00 26.94 ? 484 PHE B CD1 1 ATOM 7864 C CD2 . PHE B 1 484 ? -41.395 -1.205 294.398 1.00 25.07 ? 484 PHE B CD2 1 ATOM 7865 C CE1 . PHE B 1 484 ? -42.948 -1.719 292.179 1.00 25.99 ? 484 PHE B CE1 1 ATOM 7866 C CE2 . PHE B 1 484 ? -41.253 -0.431 293.262 1.00 25.13 ? 484 PHE B CE2 1 ATOM 7867 C CZ . PHE B 1 484 ? -42.030 -0.689 292.151 1.00 23.95 ? 484 PHE B CZ 1 ATOM 7868 N N . ASP B 1 485 ? -40.550 -5.102 293.702 1.00 26.10 ? 485 ASP B N 1 ATOM 7869 C CA . ASP B 1 485 ? -39.242 -5.248 293.067 1.00 24.92 ? 485 ASP B CA 1 ATOM 7870 C C . ASP B 1 485 ? -38.937 -3.946 292.339 1.00 27.06 ? 485 ASP B C 1 ATOM 7871 O O . ASP B 1 485 ? -39.254 -3.779 291.162 1.00 27.67 ? 485 ASP B O 1 ATOM 7872 C CB . ASP B 1 485 ? -39.232 -6.442 292.121 1.00 27.25 ? 485 ASP B CB 1 ATOM 7873 C CG . ASP B 1 485 ? -37.832 -6.828 291.674 1.00 29.70 ? 485 ASP B CG 1 ATOM 7874 O OD1 . ASP B 1 485 ? -36.926 -5.971 291.709 1.00 31.09 ? 485 ASP B OD1 1 ATOM 7875 O OD2 . ASP B 1 485 ? -37.640 -7.998 291.280 1.00 37.10 ? 485 ASP B OD2 1 ATOM 7876 N N . SER B 1 486 ? -38.302 -3.012 293.051 1.00 33.30 ? 486 SER B N 1 ATOM 7877 C CA . SER B 1 486 ? -37.971 -1.714 292.472 1.00 30.53 ? 486 SER B CA 1 ATOM 7878 C C . SER B 1 486 ? -37.010 -1.819 291.296 1.00 30.84 ? 486 SER B C 1 ATOM 7879 O O . SER B 1 486 ? -36.868 -0.845 290.547 1.00 33.29 ? 486 SER B O 1 ATOM 7880 C CB . SER B 1 486 ? -37.381 -0.799 293.547 1.00 28.92 ? 486 SER B CB 1 ATOM 7881 O OG . SER B 1 486 ? -36.255 -1.396 294.164 1.00 33.80 ? 486 SER B OG 1 ATOM 7882 N N . ALA B 1 487 ? -36.348 -2.963 291.114 1.00 29.61 ? 487 ALA B N 1 ATOM 7883 C CA . ALA B 1 487 ? -35.501 -3.155 289.942 1.00 31.02 ? 487 ALA B CA 1 ATOM 7884 C C . ALA B 1 487 ? -36.336 -3.439 288.702 1.00 34.23 ? 487 ALA B C 1 ATOM 7885 O O . ALA B 1 487 ? -36.149 -2.805 287.657 1.00 30.42 ? 487 ALA B O 1 ATOM 7886 C CB . ALA B 1 487 ? -34.507 -4.290 290.193 1.00 37.47 ? 487 ALA B CB 1 ATOM 7887 N N . ALA B 1 488 ? -37.263 -4.388 288.801 1.00 31.09 ? 488 ALA B N 1 ATOM 7888 C CA . ALA B 1 488 ? -38.148 -4.733 287.700 1.00 29.13 ? 488 ALA B CA 1 ATOM 7889 C C . ALA B 1 488 ? -39.427 -3.909 287.681 1.00 36.46 ? 488 ALA B C 1 ATOM 7890 O O . ALA B 1 488 ? -40.182 -3.994 286.707 1.00 33.24 ? 488 ALA B O 1 ATOM 7891 C CB . ALA B 1 488 ? -38.506 -6.220 287.761 1.00 42.30 ? 488 ALA B CB 1 ATOM 7892 N N . GLN B 1 489 ? -39.676 -3.114 288.722 1.00 34.20 ? 489 GLN B N 1 ATOM 7893 C CA . GLN B 1 489 ? -40.931 -2.384 288.889 1.00 30.12 ? 489 GLN B CA 1 ATOM 7894 C C . GLN B 1 489 ? -42.122 -3.335 288.801 1.00 29.25 ? 489 GLN B C 1 ATOM 7895 O O . GLN B 1 489 ? -43.053 -3.146 288.015 1.00 48.11 ? 489 GLN B O 1 ATOM 7896 C CB . GLN B 1 489 ? -41.050 -1.243 287.876 1.00 33.95 ? 489 GLN B CB 1 ATOM 7897 C CG . GLN B 1 489 ? -39.921 -0.229 287.959 1.00 30.03 ? 489 GLN B CG 1 ATOM 7898 C CD . GLN B 1 489 ? -40.130 0.955 287.037 1.00 35.97 ? 489 GLN B CD 1 ATOM 7899 O OE1 . GLN B 1 489 ? -40.261 0.797 285.824 1.00 42.10 ? 489 GLN B OE1 1 ATOM 7900 N NE2 . GLN B 1 489 ? -40.163 2.152 287.610 1.00 47.60 ? 489 GLN B NE2 1 ATOM 7901 N N . ALA B 1 490 ? -42.074 -4.382 289.621 1.00 32.10 ? 490 ALA B N 1 ATOM 7902 C CA . ALA B 1 490 ? -43.124 -5.383 289.687 1.00 35.99 ? 490 ALA B CA 1 ATOM 7903 C C . ALA B 1 490 ? -43.477 -5.653 291.142 1.00 28.28 ? 490 ALA B C 1 ATOM 7904 O O . ALA B 1 490 ? -42.690 -5.388 292.054 1.00 24.93 ? 490 ALA B O 1 ATOM 7905 C CB . ALA B 1 490 ? -42.708 -6.688 289.000 1.00 26.62 ? 490 ALA B CB 1 ATOM 7906 N N . SER B 1 491 ? -44.675 -6.192 291.347 1.00 29.59 ? 491 SER B N 1 ATOM 7907 C CA . SER B 1 491 ? -45.189 -6.458 292.680 1.00 28.04 ? 491 SER B CA 1 ATOM 7908 C C . SER B 1 491 ? -45.672 -7.897 292.771 1.00 26.92 ? 491 SER B C 1 ATOM 7909 O O . SER B 1 491 ? -46.114 -8.486 291.781 1.00 24.24 ? 491 SER B O 1 ATOM 7910 C CB . SER B 1 491 ? -46.337 -5.505 293.039 1.00 34.98 ? 491 SER B CB 1 ATOM 7911 O OG . SER B 1 491 ? -45.921 -4.152 292.963 1.00 43.83 ? 491 SER B OG 1 ATOM 7912 N N . TYR B 1 492 ? -45.579 -8.456 293.975 1.00 26.29 ? 492 TYR B N 1 ATOM 7913 C CA . TYR B 1 492 ? -46.122 -9.779 294.244 1.00 25.79 ? 492 TYR B CA 1 ATOM 7914 C C . TYR B 1 492 ? -46.396 -9.895 295.735 1.00 26.24 ? 492 TYR B C 1 ATOM 7915 O O . TYR B 1 492 ? -45.862 -9.134 296.545 1.00 24.37 ? 492 TYR B O 1 ATOM 7916 C CB . TYR B 1 492 ? -45.179 -10.893 293.771 1.00 28.39 ? 492 TYR B CB 1 ATOM 7917 C CG . TYR B 1 492 ? -43.810 -10.896 294.419 1.00 30.69 ? 492 TYR B CG 1 ATOM 7918 C CD1 . TYR B 1 492 ? -43.595 -11.526 295.640 1.00 30.31 ? 492 TYR B CD1 1 ATOM 7919 C CD2 . TYR B 1 492 ? -42.730 -10.280 293.804 1.00 39.02 ? 492 TYR B CD2 1 ATOM 7920 C CE1 . TYR B 1 492 ? -42.346 -11.534 296.230 1.00 31.37 ? 492 TYR B CE1 1 ATOM 7921 C CE2 . TYR B 1 492 ? -41.477 -10.284 294.385 1.00 31.94 ? 492 TYR B CE2 1 ATOM 7922 C CZ . TYR B 1 492 ? -41.290 -10.912 295.597 1.00 32.22 ? 492 TYR B CZ 1 ATOM 7923 O OH . TYR B 1 492 ? -40.043 -10.916 296.178 1.00 31.44 ? 492 TYR B OH 1 ATOM 7924 N N . VAL B 1 493 ? -47.240 -10.865 296.083 1.00 27.38 ? 493 VAL B N 1 ATOM 7925 C CA . VAL B 1 493 ? -47.612 -11.128 297.464 1.00 27.36 ? 493 VAL B CA 1 ATOM 7926 C C . VAL B 1 493 ? -47.361 -12.598 297.764 1.00 27.96 ? 493 VAL B C 1 ATOM 7927 O O . VAL B 1 493 ? -47.335 -13.445 296.869 1.00 30.19 ? 493 VAL B O 1 ATOM 7928 C CB . VAL B 1 493 ? -49.083 -10.763 297.751 1.00 26.47 ? 493 VAL B CB 1 ATOM 7929 C CG1 . VAL B 1 493 ? -49.268 -9.256 297.740 1.00 40.17 ? 493 VAL B CG1 1 ATOM 7930 C CG2 . VAL B 1 493 ? -50.001 -11.426 296.736 1.00 24.60 ? 493 VAL B CG2 1 ATOM 7931 N N . PHE B 1 494 ? -47.174 -12.896 299.048 1.00 28.12 ? 494 PHE B N 1 ATOM 7932 C CA . PHE B 1 494 ? -46.917 -14.264 299.470 1.00 28.61 ? 494 PHE B CA 1 ATOM 7933 C C . PHE B 1 494 ? -47.514 -14.501 300.848 1.00 27.74 ? 494 PHE B C 1 ATOM 7934 O O . PHE B 1 494 ? -47.496 -13.613 301.704 1.00 39.37 ? 494 PHE B O 1 ATOM 7935 C CB . PHE B 1 494 ? -45.419 -14.575 299.490 1.00 31.22 ? 494 PHE B CB 1 ATOM 7936 C CG . PHE B 1 494 ? -45.110 -16.037 299.631 1.00 34.31 ? 494 PHE B CG 1 ATOM 7937 C CD1 . PHE B 1 494 ? -45.193 -16.881 298.539 1.00 33.90 ? 494 PHE B CD1 1 ATOM 7938 C CD2 . PHE B 1 494 ? -44.744 -16.569 300.856 1.00 36.21 ? 494 PHE B CD2 1 ATOM 7939 C CE1 . PHE B 1 494 ? -44.914 -18.228 298.661 1.00 35.44 ? 494 PHE B CE1 1 ATOM 7940 C CE2 . PHE B 1 494 ? -44.463 -17.916 300.984 1.00 35.51 ? 494 PHE B CE2 1 ATOM 7941 C CZ . PHE B 1 494 ? -44.548 -18.746 299.886 1.00 39.84 ? 494 PHE B CZ 1 ATOM 7942 N N . ASP B 1 495 ? -48.035 -15.709 301.051 1.00 29.72 ? 495 ASP B N 1 ATOM 7943 C CA . ASP B 1 495 ? -48.606 -16.133 302.325 1.00 31.02 ? 495 ASP B CA 1 ATOM 7944 C C . ASP B 1 495 ? -47.827 -17.349 302.809 1.00 37.55 ? 495 ASP B C 1 ATOM 7945 O O . ASP B 1 495 ? -47.896 -18.419 302.196 1.00 33.69 ? 495 ASP B O 1 ATOM 7946 C CB . ASP B 1 495 ? -50.093 -16.452 302.181 1.00 36.11 ? 495 ASP B CB 1 ATOM 7947 C CG . ASP B 1 495 ? -50.746 -16.806 303.502 1.00 39.58 ? 495 ASP B CG 1 ATOM 7948 O OD1 . ASP B 1 495 ? -50.159 -16.499 304.562 1.00 33.49 ? 495 ASP B OD1 1 ATOM 7949 O OD2 . ASP B 1 495 ? -51.851 -17.389 303.482 1.00 33.38 ? 495 ASP B OD2 1 ATOM 7950 N N . LYS B 1 496 ? -47.089 -17.183 303.909 1.00 49.10 ? 496 LYS B N 1 ATOM 7951 C CA . LYS B 1 496 ? -46.292 -18.278 304.450 1.00 42.85 ? 496 LYS B CA 1 ATOM 7952 C C . LYS B 1 496 ? -47.151 -19.410 305.001 1.00 37.14 ? 496 LYS B C 1 ATOM 7953 O O . LYS B 1 496 ? -46.644 -20.523 305.177 1.00 37.13 ? 496 LYS B O 1 ATOM 7954 C CB . LYS B 1 496 ? -45.362 -17.759 305.548 1.00 40.90 ? 496 LYS B CB 1 ATOM 7955 C CG . LYS B 1 496 ? -43.901 -18.147 305.376 1.00 52.98 ? 496 LYS B CG 1 ATOM 7956 C CD . LYS B 1 496 ? -43.273 -17.437 304.189 1.00 54.35 ? 496 LYS B CD 1 ATOM 7957 C CE . LYS B 1 496 ? -41.802 -17.791 304.049 1.00 53.95 ? 496 LYS B CE 1 ATOM 7958 N NZ . LYS B 1 496 ? -41.593 -19.256 303.890 1.00 45.27 ? 496 LYS B NZ 1 ATOM 7959 N N . SER B 1 497 ? -48.433 -19.156 305.274 1.00 32.93 ? 497 SER B N 1 ATOM 7960 C CA . SER B 1 497 ? -49.268 -20.178 305.896 1.00 32.81 ? 497 SER B CA 1 ATOM 7961 C C . SER B 1 497 ? -49.618 -21.288 304.913 1.00 31.11 ? 497 SER B C 1 ATOM 7962 O O . SER B 1 497 ? -49.560 -22.473 305.263 1.00 33.62 ? 497 SER B O 1 ATOM 7963 C CB . SER B 1 497 ? -50.537 -19.545 306.466 1.00 39.40 ? 497 SER B CB 1 ATOM 7964 O OG . SER B 1 497 ? -51.384 -19.076 305.433 1.00 57.94 ? 497 SER B OG 1 ATOM 7965 N N . LYS B 1 498 ? -49.984 -20.932 303.679 1.00 31.50 ? 498 LYS B N 1 ATOM 7966 C CA . LYS B 1 498 ? -50.363 -21.925 302.682 1.00 35.50 ? 498 LYS B CA 1 ATOM 7967 C C . LYS B 1 498 ? -49.581 -21.783 301.380 1.00 33.25 ? 498 LYS B C 1 ATOM 7968 O O . LYS B 1 498 ? -49.938 -22.424 300.385 1.00 36.62 ? 498 LYS B O 1 ATOM 7969 C CB . LYS B 1 498 ? -51.869 -21.858 302.399 1.00 54.55 ? 498 LYS B CB 1 ATOM 7970 C CG . LYS B 1 498 ? -52.501 -23.212 302.090 1.00 75.80 ? 498 LYS B CG 1 ATOM 7971 C CD . LYS B 1 498 ? -53.954 -23.072 301.662 1.00 67.18 ? 498 LYS B CD 1 ATOM 7972 C CE . LYS B 1 498 ? -54.554 -24.423 301.303 1.00 50.14 ? 498 LYS B CE 1 ATOM 7973 N NZ . LYS B 1 498 ? -53.623 -25.246 300.481 1.00 47.42 ? 498 LYS B NZ 1 ATOM 7974 N N . GLY B 1 499 ? -48.532 -20.966 301.358 1.00 31.92 ? 499 GLY B N 1 ATOM 7975 C CA . GLY B 1 499 ? -47.672 -20.887 300.186 1.00 34.66 ? 499 GLY B CA 1 ATOM 7976 C C . GLY B 1 499 ? -48.338 -20.332 298.946 1.00 37.58 ? 499 GLY B C 1 ATOM 7977 O O . GLY B 1 499 ? -48.133 -20.860 297.846 1.00 35.06 ? 499 GLY B O 1 ATOM 7978 N N . ASP B 1 500 ? -49.131 -19.275 299.096 1.00 39.32 ? 500 ASP B N 1 ATOM 7979 C CA . ASP B 1 500 ? -49.783 -18.629 297.963 1.00 36.48 ? 500 ASP B CA 1 ATOM 7980 C C . ASP B 1 500 ? -48.904 -17.488 297.464 1.00 29.80 ? 500 ASP B C 1 ATOM 7981 O O . ASP B 1 500 ? -48.691 -16.505 298.180 1.00 29.16 ? 500 ASP B O 1 ATOM 7982 C CB . ASP B 1 500 ? -51.166 -18.110 298.353 1.00 41.06 ? 500 ASP B CB 1 ATOM 7983 C CG . ASP B 1 500 ? -52.147 -19.227 298.646 1.00 59.62 ? 500 ASP B CG 1 ATOM 7984 O OD1 . ASP B 1 500 ? -52.010 -20.313 298.044 1.00 52.43 ? 500 ASP B OD1 1 ATOM 7985 O OD2 . ASP B 1 500 ? -53.057 -19.018 299.475 1.00 65.03 ? 500 ASP B OD2 1 ATOM 7986 N N . LEU B 1 501 ? -48.398 -17.620 296.240 1.00 27.67 ? 501 LEU B N 1 ATOM 7987 C CA . LEU B 1 501 ? -47.535 -16.619 295.619 1.00 26.94 ? 501 LEU B CA 1 ATOM 7988 C C . LEU B 1 501 ? -48.246 -16.075 294.388 1.00 25.23 ? 501 LEU B C 1 ATOM 7989 O O . LEU B 1 501 ? -48.388 -16.785 293.389 1.00 25.93 ? 501 LEU B O 1 ATOM 7990 C CB . LEU B 1 501 ? -46.182 -17.221 295.243 1.00 29.50 ? 501 LEU B CB 1 ATOM 7991 C CG . LEU B 1 501 ? -45.234 -16.318 294.452 1.00 29.81 ? 501 LEU B CG 1 ATOM 7992 C CD1 . LEU B 1 501 ? -44.724 -15.177 295.318 1.00 32.38 ? 501 LEU B CD1 1 ATOM 7993 C CD2 . LEU B 1 501 ? -44.080 -17.124 293.881 1.00 33.15 ? 501 LEU B CD2 1 ATOM 7994 N N . ILE B 1 502 ? -48.676 -14.817 294.452 1.00 27.81 ? 502 ILE B N 1 ATOM 7995 C CA . ILE B 1 502 ? -49.435 -14.182 293.380 1.00 30.36 ? 502 ILE B CA 1 ATOM 7996 C C . ILE B 1 502 ? -48.625 -13.018 292.830 1.00 28.14 ? 502 ILE B C 1 ATOM 7997 O O . ILE B 1 502 ? -48.173 -12.155 293.591 1.00 26.59 ? 502 ILE B O 1 ATOM 7998 C CB . ILE B 1 502 ? -50.813 -13.699 293.869 1.00 27.11 ? 502 ILE B CB 1 ATOM 7999 C CG1 . ILE B 1 502 ? -51.612 -14.864 294.453 1.00 40.72 ? 502 ILE B CG1 1 ATOM 8000 C CG2 . ILE B 1 502 ? -51.580 -13.040 292.733 1.00 29.43 ? 502 ILE B CG2 1 ATOM 8001 C CD1 . ILE B 1 502 ? -52.903 -14.442 295.118 1.00 28.81 ? 502 ILE B CD1 1 ATOM 8002 N N . SER B 1 503 ? -48.448 -12.994 291.511 1.00 27.40 ? 503 SER B N 1 ATOM 8003 C CA . SER B 1 503 ? -47.787 -11.894 290.820 1.00 28.05 ? 503 SER B CA 1 ATOM 8004 C C . SER B 1 503 ? -48.849 -11.036 290.143 1.00 28.06 ? 503 SER B C 1 ATOM 8005 O O . SER B 1 503 ? -49.573 -11.519 289.266 1.00 28.83 ? 503 SER B O 1 ATOM 8006 C CB . SER B 1 503 ? -46.783 -12.416 289.793 1.00 31.31 ? 503 SER B CB 1 ATOM 8007 O OG . SER B 1 503 ? -46.366 -11.383 288.918 1.00 37.33 ? 503 SER B OG 1 ATOM 8008 N N . PHE B 1 504 ? -48.937 -9.770 290.544 1.00 30.15 ? 504 PHE B N 1 ATOM 8009 C CA . PHE B 1 504 ? -49.982 -8.878 290.064 1.00 39.70 ? 504 PHE B CA 1 ATOM 8010 C C . PHE B 1 504 ? -49.408 -7.479 289.889 1.00 31.40 ? 504 PHE B C 1 ATOM 8011 O O . PHE B 1 504 ? -48.222 -7.233 290.130 1.00 51.23 ? 504 PHE B O 1 ATOM 8012 C CB . PHE B 1 504 ? -51.175 -8.866 291.027 1.00 34.72 ? 504 PHE B CB 1 ATOM 8013 C CG . PHE B 1 504 ? -50.905 -8.144 292.315 1.00 31.22 ? 504 PHE B CG 1 ATOM 8014 C CD1 . PHE B 1 504 ? -50.197 -8.758 293.332 1.00 30.90 ? 504 PHE B CD1 1 ATOM 8015 C CD2 . PHE B 1 504 ? -51.372 -6.856 292.514 1.00 29.21 ? 504 PHE B CD2 1 ATOM 8016 C CE1 . PHE B 1 504 ? -49.949 -8.098 294.517 1.00 30.53 ? 504 PHE B CE1 1 ATOM 8017 C CE2 . PHE B 1 504 ? -51.128 -6.192 293.700 1.00 23.91 ? 504 PHE B CE2 1 ATOM 8018 C CZ . PHE B 1 504 ? -50.416 -6.814 294.702 1.00 27.52 ? 504 PHE B CZ 1 ATOM 8019 N N . ASP B 1 505 ? -50.268 -6.555 289.467 1.00 25.55 ? 505 ASP B N 1 ATOM 8020 C CA . ASP B 1 505 ? -49.912 -5.151 289.293 1.00 26.40 ? 505 ASP B CA 1 ATOM 8021 C C . ASP B 1 505 ? -50.568 -4.343 290.405 1.00 25.61 ? 505 ASP B C 1 ATOM 8022 O O . ASP B 1 505 ? -51.795 -4.199 290.435 1.00 25.23 ? 505 ASP B O 1 ATOM 8023 C CB . ASP B 1 505 ? -50.342 -4.638 287.920 1.00 28.03 ? 505 ASP B CB 1 ATOM 8024 C CG . ASP B 1 505 ? -49.207 -4.635 286.918 1.00 33.76 ? 505 ASP B CG 1 ATOM 8025 O OD1 . ASP B 1 505 ? -48.036 -4.555 287.344 1.00 31.18 ? 505 ASP B OD1 1 ATOM 8026 O OD2 . ASP B 1 505 ? -49.486 -4.705 285.702 1.00 45.26 ? 505 ASP B OD2 1 ATOM 8027 N N . SER B 1 506 ? -49.753 -3.824 291.318 1.00 25.56 ? 506 SER B N 1 ATOM 8028 C CA . SER B 1 506 ? -50.233 -2.949 292.372 1.00 22.61 ? 506 SER B CA 1 ATOM 8029 C C . SER B 1 506 ? -50.176 -1.499 291.899 1.00 21.47 ? 506 SER B C 1 ATOM 8030 O O . SER B 1 506 ? -49.819 -1.206 290.757 1.00 23.71 ? 506 SER B O 1 ATOM 8031 C CB . SER B 1 506 ? -49.413 -3.145 293.646 1.00 23.92 ? 506 SER B CB 1 ATOM 8032 O OG . SER B 1 506 ? -48.081 -2.700 293.464 1.00 22.41 ? 506 SER B OG 1 ATOM 8033 N N . VAL B 1 507 ? -50.532 -0.573 292.793 1.00 19.88 ? 507 VAL B N 1 ATOM 8034 C CA . VAL B 1 507 ? -50.443 0.846 292.459 1.00 20.48 ? 507 VAL B CA 1 ATOM 8035 C C . VAL B 1 507 ? -49.002 1.226 292.143 1.00 24.32 ? 507 VAL B C 1 ATOM 8036 O O . VAL B 1 507 ? -48.740 2.054 291.261 1.00 25.72 ? 507 VAL B O 1 ATOM 8037 C CB . VAL B 1 507 ? -51.017 1.702 293.603 1.00 21.14 ? 507 VAL B CB 1 ATOM 8038 C CG1 . VAL B 1 507 ? -50.988 3.177 293.233 1.00 23.55 ? 507 VAL B CG1 1 ATOM 8039 C CG2 . VAL B 1 507 ? -52.432 1.261 293.937 1.00 23.36 ? 507 VAL B CG2 1 ATOM 8040 N N . ASP B 1 508 ? -48.046 0.615 292.845 1.00 27.65 ? 508 ASP B N 1 ATOM 8041 C CA . ASP B 1 508 ? -46.637 0.921 292.616 1.00 25.05 ? 508 ASP B CA 1 ATOM 8042 C C . ASP B 1 508 ? -46.208 0.513 291.213 1.00 24.83 ? 508 ASP B C 1 ATOM 8043 O O . ASP B 1 508 ? -45.635 1.316 290.467 1.00 43.29 ? 508 ASP B O 1 ATOM 8044 C CB . ASP B 1 508 ? -45.775 0.219 293.664 1.00 24.70 ? 508 ASP B CB 1 ATOM 8045 C CG . ASP B 1 508 ? -46.181 0.566 295.078 1.00 26.77 ? 508 ASP B CG 1 ATOM 8046 O OD1 . ASP B 1 508 ? -46.580 1.725 295.314 1.00 43.37 ? 508 ASP B OD1 1 ATOM 8047 O OD2 . ASP B 1 508 ? -46.105 -0.322 295.953 1.00 26.86 ? 508 ASP B OD2 1 ATOM 8048 N N . SER B 1 509 ? -46.479 -0.738 290.835 1.00 23.10 ? 509 SER B N 1 ATOM 8049 C CA . SER B 1 509 ? -46.035 -1.233 289.537 1.00 27.94 ? 509 SER B CA 1 ATOM 8050 C C . SER B 1 509 ? -46.749 -0.521 288.395 1.00 27.35 ? 509 SER B C 1 ATOM 8051 O O . SER B 1 509 ? -46.153 -0.279 287.340 1.00 25.05 ? 509 SER B O 1 ATOM 8052 C CB . SER B 1 509 ? -46.256 -2.741 289.450 1.00 29.42 ? 509 SER B CB 1 ATOM 8053 O OG . SER B 1 509 ? -47.624 -3.054 289.627 1.00 25.02 ? 509 SER B OG 1 ATOM 8054 N N . VAL B 1 510 ? -48.026 -0.181 288.582 1.00 28.01 ? 510 VAL B N 1 ATOM 8055 C CA . VAL B 1 510 ? -48.741 0.581 287.561 1.00 28.67 ? 510 VAL B CA 1 ATOM 8056 C C . VAL B 1 510 ? -48.106 1.953 287.387 1.00 30.17 ? 510 VAL B C 1 ATOM 8057 O O . VAL B 1 510 ? -47.903 2.423 286.260 1.00 42.61 ? 510 VAL B O 1 ATOM 8058 C CB . VAL B 1 510 ? -50.235 0.691 287.916 1.00 26.95 ? 510 VAL B CB 1 ATOM 8059 C CG1 . VAL B 1 510 ? -50.937 1.630 286.951 1.00 27.96 ? 510 VAL B CG1 1 ATOM 8060 C CG2 . VAL B 1 510 ? -50.889 -0.679 287.878 1.00 27.72 ? 510 VAL B CG2 1 ATOM 8061 N N . LEU B 1 511 ? -47.775 2.613 288.500 1.00 36.98 ? 511 LEU B N 1 ATOM 8062 C CA . LEU B 1 511 ? -47.123 3.915 288.417 1.00 30.48 ? 511 LEU B CA 1 ATOM 8063 C C . LEU B 1 511 ? -45.781 3.814 287.701 1.00 35.59 ? 511 LEU B C 1 ATOM 8064 O O . LEU B 1 511 ? -45.392 4.726 286.960 1.00 54.96 ? 511 LEU B O 1 ATOM 8065 C CB . LEU B 1 511 ? -46.949 4.500 289.817 1.00 29.14 ? 511 LEU B CB 1 ATOM 8066 C CG . LEU B 1 511 ? -47.263 5.976 289.965 1.00 37.50 ? 511 LEU B CG 1 ATOM 8067 C CD1 . LEU B 1 511 ? -48.738 6.215 289.837 1.00 37.37 ? 511 LEU B CD1 1 ATOM 8068 C CD2 . LEU B 1 511 ? -46.738 6.520 291.278 1.00 73.47 ? 511 LEU B CD2 1 ATOM 8069 N N . GLY B 1 512 ? -45.063 2.707 287.901 1.00 34.69 ? 512 GLY B N 1 ATOM 8070 C CA . GLY B 1 512 ? -43.839 2.488 287.148 1.00 32.03 ? 512 GLY B CA 1 ATOM 8071 C C . GLY B 1 512 ? -44.090 2.375 285.658 1.00 27.29 ? 512 GLY B C 1 ATOM 8072 O O . GLY B 1 512 ? -43.298 2.858 284.846 1.00 29.07 ? 512 GLY B O 1 ATOM 8073 N N . LYS B 1 513 ? -45.201 1.738 285.277 1.00 24.04 ? 513 LYS B N 1 ATOM 8074 C CA . LYS B 1 513 ? -45.571 1.685 283.868 1.00 26.02 ? 513 LYS B CA 1 ATOM 8075 C C . LYS B 1 513 ? -45.948 3.062 283.341 1.00 28.09 ? 513 LYS B C 1 ATOM 8076 O O . LYS B 1 513 ? -45.740 3.349 282.157 1.00 27.35 ? 513 LYS B O 1 ATOM 8077 C CB . LYS B 1 513 ? -46.726 0.706 283.660 1.00 24.51 ? 513 LYS B CB 1 ATOM 8078 C CG . LYS B 1 513 ? -46.407 -0.731 284.033 1.00 22.80 ? 513 LYS B CG 1 ATOM 8079 C CD . LYS B 1 513 ? -47.545 -1.658 283.640 1.00 23.96 ? 513 LYS B CD 1 ATOM 8080 C CE . LYS B 1 513 ? -47.208 -3.109 283.938 1.00 26.03 ? 513 LYS B CE 1 ATOM 8081 N NZ . LYS B 1 513 ? -48.290 -4.028 283.490 1.00 24.39 ? 513 LYS B NZ 1 ATOM 8082 N N . VAL B 1 514 ? -46.503 3.922 284.198 1.00 29.11 ? 514 VAL B N 1 ATOM 8083 C CA . VAL B 1 514 ? -46.845 5.277 283.777 1.00 27.84 ? 514 VAL B CA 1 ATOM 8084 C C . VAL B 1 514 ? -45.584 6.057 283.427 1.00 29.30 ? 514 VAL B C 1 ATOM 8085 O O . VAL B 1 514 ? -45.478 6.644 282.344 1.00 30.58 ? 514 VAL B O 1 ATOM 8086 C CB . VAL B 1 514 ? -47.661 5.990 284.869 1.00 26.41 ? 514 VAL B CB 1 ATOM 8087 C CG1 . VAL B 1 514 ? -47.962 7.419 284.454 1.00 42.34 ? 514 VAL B CG1 1 ATOM 8088 C CG2 . VAL B 1 514 ? -48.948 5.234 285.151 1.00 27.07 ? 514 VAL B CG2 1 ATOM 8089 N N . LYS B 1 515 ? -44.607 6.067 284.337 1.00 29.31 ? 515 LYS B N 1 ATOM 8090 C CA . LYS B 1 515 ? -43.373 6.800 284.081 1.00 29.79 ? 515 LYS B CA 1 ATOM 8091 C C . LYS B 1 515 ? -42.541 6.141 282.988 1.00 28.91 ? 515 LYS B C 1 ATOM 8092 O O . LYS B 1 515 ? -41.773 6.826 282.303 1.00 29.39 ? 515 LYS B O 1 ATOM 8093 C CB . LYS B 1 515 ? -42.564 6.933 285.370 1.00 31.31 ? 515 LYS B CB 1 ATOM 8094 C CG . LYS B 1 515 ? -43.357 7.528 286.524 1.00 40.79 ? 515 LYS B CG 1 ATOM 8095 C CD . LYS B 1 515 ? -43.078 6.812 287.834 1.00 58.89 ? 515 LYS B CD 1 ATOM 8096 C CE . LYS B 1 515 ? -41.601 6.846 288.182 1.00 64.87 ? 515 LYS B CE 1 ATOM 8097 N NZ . LYS B 1 515 ? -41.326 6.148 289.468 1.00 63.89 ? 515 LYS B NZ 1 ATOM 8098 N N . TYR B 1 516 ? -42.674 4.825 282.806 1.00 28.61 ? 516 TYR B N 1 ATOM 8099 C CA . TYR B 1 516 ? -42.012 4.183 281.676 1.00 28.00 ? 516 TYR B CA 1 ATOM 8100 C C . TYR B 1 516 ? -42.625 4.624 280.354 1.00 28.74 ? 516 TYR B C 1 ATOM 8101 O O . TYR B 1 516 ? -41.922 4.705 279.341 1.00 29.30 ? 516 TYR B O 1 ATOM 8102 C CB . TYR B 1 516 ? -42.077 2.661 281.811 1.00 28.83 ? 516 TYR B CB 1 ATOM 8103 C CG . TYR B 1 516 ? -41.323 1.929 280.724 1.00 31.24 ? 516 TYR B CG 1 ATOM 8104 C CD1 . TYR B 1 516 ? -39.961 1.688 280.838 1.00 28.84 ? 516 TYR B CD1 1 ATOM 8105 C CD2 . TYR B 1 516 ? -41.973 1.482 279.581 1.00 35.17 ? 516 TYR B CD2 1 ATOM 8106 C CE1 . TYR B 1 516 ? -39.267 1.023 279.846 1.00 32.34 ? 516 TYR B CE1 1 ATOM 8107 C CE2 . TYR B 1 516 ? -41.288 0.816 278.583 1.00 32.55 ? 516 TYR B CE2 1 ATOM 8108 C CZ . TYR B 1 516 ? -39.936 0.589 278.721 1.00 34.33 ? 516 TYR B CZ 1 ATOM 8109 O OH . TYR B 1 516 ? -39.253 -0.073 277.728 1.00 56.61 ? 516 TYR B OH 1 ATOM 8110 N N . VAL B 1 517 ? -43.928 4.911 280.344 1.00 30.70 ? 517 VAL B N 1 ATOM 8111 C CA . VAL B 1 517 ? -44.572 5.417 279.138 1.00 30.91 ? 517 VAL B CA 1 ATOM 8112 C C . VAL B 1 517 ? -44.202 6.878 278.909 1.00 31.03 ? 517 VAL B C 1 ATOM 8113 O O . VAL B 1 517 ? -43.975 7.306 277.771 1.00 31.54 ? 517 VAL B O 1 ATOM 8114 C CB . VAL B 1 517 ? -46.096 5.221 279.234 1.00 32.57 ? 517 VAL B CB 1 ATOM 8115 C CG1 . VAL B 1 517 ? -46.820 6.072 278.206 1.00 40.31 ? 517 VAL B CG1 1 ATOM 8116 C CG2 . VAL B 1 517 ? -46.451 3.755 279.052 1.00 35.17 ? 517 VAL B CG2 1 ATOM 8117 N N . ASP B 1 518 ? -44.117 7.660 279.987 1.00 29.86 ? 518 ASP B N 1 ATOM 8118 C CA . ASP B 1 518 ? -43.858 9.090 279.862 1.00 29.42 ? 518 ASP B CA 1 ATOM 8119 C C . ASP B 1 518 ? -42.463 9.354 279.308 1.00 30.45 ? 518 ASP B C 1 ATOM 8120 O O . ASP B 1 518 ? -42.304 10.034 278.287 1.00 30.38 ? 518 ASP B O 1 ATOM 8121 C CB . ASP B 1 518 ? -44.034 9.771 281.220 1.00 30.08 ? 518 ASP B CB 1 ATOM 8122 C CG . ASP B 1 518 ? -45.448 9.655 281.748 1.00 31.99 ? 518 ASP B CG 1 ATOM 8123 O OD1 . ASP B 1 518 ? -46.366 9.408 280.938 1.00 42.89 ? 518 ASP B OD1 1 ATOM 8124 O OD2 . ASP B 1 518 ? -45.643 9.812 282.971 1.00 31.08 ? 518 ASP B OD2 1 ATOM 8125 N N . ARG B 1 519 ? -41.435 8.820 279.973 1.00 33.10 ? 519 ARG B N 1 ATOM 8126 C CA . ARG B 1 519 ? -40.062 9.110 279.573 1.00 34.32 ? 519 ARG B CA 1 ATOM 8127 C C . ARG B 1 519 ? -39.726 8.521 278.209 1.00 33.17 ? 519 ARG B C 1 ATOM 8128 O O . ARG B 1 519 ? -38.853 9.047 277.509 1.00 33.55 ? 519 ARG B O 1 ATOM 8129 C CB . ARG B 1 519 ? -39.085 8.583 280.624 1.00 33.20 ? 519 ARG B CB 1 ATOM 8130 C CG . ARG B 1 519 ? -39.434 8.967 282.052 1.00 44.53 ? 519 ARG B CG 1 ATOM 8131 C CD . ARG B 1 519 ? -38.530 8.254 283.043 1.00 39.16 ? 519 ARG B CD 1 ATOM 8132 N NE . ARG B 1 519 ? -39.002 8.395 284.417 1.00 38.44 ? 519 ARG B NE 1 ATOM 8133 C CZ . ARG B 1 519 ? -38.445 9.198 285.317 1.00 37.75 ? 519 ARG B CZ 1 ATOM 8134 N NH1 . ARG B 1 519 ? -37.397 9.936 284.985 1.00 36.47 ? 519 ARG B NH1 1 ATOM 8135 N NH2 . ARG B 1 519 ? -38.937 9.265 286.546 1.00 51.60 ? 519 ARG B NH2 1 ATOM 8136 N N . ASN B 1 520 ? -40.398 7.442 277.814 1.00 32.75 ? 520 ASN B N 1 ATOM 8137 C CA . ASN B 1 520 ? -40.097 6.752 276.568 1.00 35.21 ? 520 ASN B CA 1 ATOM 8138 C C . ASN B 1 520 ? -41.043 7.131 275.436 1.00 44.60 ? 520 ASN B C 1 ATOM 8139 O O . ASN B 1 520 ? -41.080 6.429 274.419 1.00 34.57 ? 520 ASN B O 1 ATOM 8140 C CB . ASN B 1 520 ? -40.120 5.238 276.783 1.00 32.52 ? 520 ASN B CB 1 ATOM 8141 C CG . ASN B 1 520 ? -38.897 4.737 277.524 1.00 41.07 ? 520 ASN B CG 1 ATOM 8142 O OD1 . ASN B 1 520 ? -37.841 4.526 276.929 1.00 34.30 ? 520 ASN B OD1 1 ATOM 8143 N ND2 . ASN B 1 520 ? -39.034 4.547 278.831 1.00 49.87 ? 520 ASN B ND2 1 ATOM 8144 N N . LYS B 1 521 ? -41.812 8.211 275.591 1.00 33.05 ? 521 LYS B N 1 ATOM 8145 C CA . LYS B 1 521 ? -42.646 8.761 274.522 1.00 34.65 ? 521 LYS B CA 1 ATOM 8146 C C . LYS B 1 521 ? -43.709 7.753 274.066 1.00 39.71 ? 521 LYS B C 1 ATOM 8147 O O . LYS B 1 521 ? -44.228 7.828 272.949 1.00 45.08 ? 521 LYS B O 1 ATOM 8148 C CB . LYS B 1 521 ? -41.747 9.240 273.365 1.00 36.39 ? 521 LYS B CB 1 ATOM 8149 C CG . LYS B 1 521 ? -42.394 9.820 272.108 1.00 54.10 ? 521 LYS B CG 1 ATOM 8150 C CD . LYS B 1 521 ? -41.324 10.229 271.105 1.00 37.22 ? 521 LYS B CD 1 ATOM 8151 C CE . LYS B 1 521 ? -41.911 10.500 269.731 1.00 37.80 ? 521 LYS B CE 1 ATOM 8152 N NZ . LYS B 1 521 ? -40.885 10.330 268.661 1.00 38.21 ? 521 LYS B NZ 1 ATOM 8153 N N . LEU B 1 522 ? -44.066 6.814 274.938 1.00 34.18 ? 522 LEU B N 1 ATOM 8154 C CA . LEU B 1 522 ? -45.007 5.770 274.570 1.00 34.15 ? 522 LEU B CA 1 ATOM 8155 C C . LEU B 1 522 ? -46.427 6.325 274.481 1.00 32.89 ? 522 LEU B C 1 ATOM 8156 O O . LEU B 1 522 ? -46.747 7.390 275.017 1.00 34.51 ? 522 LEU B O 1 ATOM 8157 C CB . LEU B 1 522 ? -44.942 4.617 275.569 1.00 38.50 ? 522 LEU B CB 1 ATOM 8158 C CG . LEU B 1 522 ? -43.593 3.901 275.618 1.00 36.05 ? 522 LEU B CG 1 ATOM 8159 C CD1 . LEU B 1 522 ? -43.612 2.778 276.637 1.00 33.72 ? 522 LEU B CD1 1 ATOM 8160 C CD2 . LEU B 1 522 ? -43.224 3.372 274.240 1.00 33.57 ? 522 LEU B CD2 1 ATOM 8161 N N . GLY B 1 523 ? -47.288 5.574 273.791 1.00 31.93 ? 523 GLY B N 1 ATOM 8162 C CA . GLY B 1 523 ? -48.613 6.082 273.476 1.00 33.03 ? 523 GLY B CA 1 ATOM 8163 C C . GLY B 1 523 ? -49.524 6.191 274.684 1.00 31.70 ? 523 GLY B C 1 ATOM 8164 O O . GLY B 1 523 ? -50.238 7.184 274.844 1.00 44.25 ? 523 GLY B O 1 ATOM 8165 N N . GLY B 1 524 ? -49.527 5.175 275.538 1.00 33.14 ? 524 GLY B N 1 ATOM 8166 C CA . GLY B 1 524 ? -50.393 5.194 276.702 1.00 27.54 ? 524 GLY B CA 1 ATOM 8167 C C . GLY B 1 524 ? -50.506 3.808 277.313 1.00 23.65 ? 524 GLY B C 1 ATOM 8168 O O . GLY B 1 524 ? -49.636 2.960 277.129 1.00 29.17 ? 524 GLY B O 1 ATOM 8169 N N . LEU B 1 525 ? -51.606 3.606 278.037 1.00 22.18 ? 525 LEU B N 1 ATOM 8170 C CA . LEU B 1 525 ? -51.838 2.383 278.791 1.00 21.86 ? 525 LEU B CA 1 ATOM 8171 C C . LEU B 1 525 ? -53.219 1.824 278.481 1.00 25.18 ? 525 LEU B C 1 ATOM 8172 O O . LEU B 1 525 ? -54.188 2.576 278.350 1.00 33.95 ? 525 LEU B O 1 ATOM 8173 C CB . LEU B 1 525 ? -51.711 2.633 280.298 1.00 19.28 ? 525 LEU B CB 1 ATOM 8174 C CG . LEU B 1 525 ? -50.338 3.076 280.803 1.00 19.98 ? 525 LEU B CG 1 ATOM 8175 C CD1 . LEU B 1 525 ? -50.421 3.537 282.246 1.00 37.47 ? 525 LEU B CD1 1 ATOM 8176 C CD2 . LEU B 1 525 ? -49.335 1.948 280.665 1.00 25.04 ? 525 LEU B CD2 1 ATOM 8177 N N . PHE B 1 526 ? -53.299 0.500 278.365 1.00 26.02 ? 526 PHE B N 1 ATOM 8178 C CA . PHE B 1 526 ? -54.564 -0.208 278.229 1.00 23.56 ? 526 PHE B CA 1 ATOM 8179 C C . PHE B 1 526 ? -54.588 -1.359 279.223 1.00 21.24 ? 526 PHE B C 1 ATOM 8180 O O . PHE B 1 526 ? -53.541 -1.889 279.604 1.00 23.75 ? 526 PHE B O 1 ATOM 8181 C CB . PHE B 1 526 ? -54.779 -0.721 276.798 1.00 24.41 ? 526 PHE B CB 1 ATOM 8182 C CG . PHE B 1 526 ? -54.052 -1.998 276.491 1.00 22.76 ? 526 PHE B CG 1 ATOM 8183 C CD1 . PHE B 1 526 ? -52.707 -1.983 276.165 1.00 23.72 ? 526 PHE B CD1 1 ATOM 8184 C CD2 . PHE B 1 526 ? -54.717 -3.212 276.511 1.00 23.65 ? 526 PHE B CD2 1 ATOM 8185 C CE1 . PHE B 1 526 ? -52.037 -3.154 275.876 1.00 26.83 ? 526 PHE B CE1 1 ATOM 8186 C CE2 . PHE B 1 526 ? -54.052 -4.388 276.224 1.00 34.28 ? 526 PHE B CE2 1 ATOM 8187 C CZ . PHE B 1 526 ? -52.709 -4.358 275.907 1.00 28.29 ? 526 PHE B CZ 1 ATOM 8188 N N . ALA B 1 527 ? -55.790 -1.747 279.643 1.00 18.75 ? 527 ALA B N 1 ATOM 8189 C CA . ALA B 1 527 ? -55.942 -2.650 280.774 1.00 19.98 ? 527 ALA B CA 1 ATOM 8190 C C . ALA B 1 527 ? -56.833 -3.835 280.428 1.00 22.36 ? 527 ALA B C 1 ATOM 8191 O O . ALA B 1 527 ? -57.670 -3.779 279.523 1.00 26.63 ? 527 ALA B O 1 ATOM 8192 C CB . ALA B 1 527 ? -56.516 -1.919 281.995 1.00 17.25 ? 527 ALA B CB 1 ATOM 8193 N N . TRP B 1 528 ? -56.625 -4.916 281.174 1.00 22.98 ? 528 TRP B N 1 ATOM 8194 C CA . TRP B 1 528 ? -57.489 -6.092 281.166 1.00 21.82 ? 528 TRP B CA 1 ATOM 8195 C C . TRP B 1 528 ? -57.547 -6.644 282.585 1.00 21.68 ? 528 TRP B C 1 ATOM 8196 O O . TRP B 1 528 ? -56.515 -7.012 283.143 1.00 24.77 ? 528 TRP B O 1 ATOM 8197 C CB . TRP B 1 528 ? -56.971 -7.164 280.200 1.00 21.82 ? 528 TRP B CB 1 ATOM 8198 C CG . TRP B 1 528 ? -57.743 -8.462 280.268 1.00 22.40 ? 528 TRP B CG 1 ATOM 8199 C CD1 . TRP B 1 528 ? -57.630 -9.434 281.221 1.00 23.91 ? 528 TRP B CD1 1 ATOM 8200 C CD2 . TRP B 1 528 ? -58.728 -8.930 279.338 1.00 25.00 ? 528 TRP B CD2 1 ATOM 8201 N NE1 . TRP B 1 528 ? -58.492 -10.467 280.951 1.00 30.10 ? 528 TRP B NE1 1 ATOM 8202 C CE2 . TRP B 1 528 ? -59.175 -10.184 279.798 1.00 25.41 ? 528 TRP B CE2 1 ATOM 8203 C CE3 . TRP B 1 528 ? -59.275 -8.411 278.162 1.00 24.45 ? 528 TRP B CE3 1 ATOM 8204 C CZ2 . TRP B 1 528 ? -60.146 -10.922 279.127 1.00 28.37 ? 528 TRP B CZ2 1 ATOM 8205 C CZ3 . TRP B 1 528 ? -60.240 -9.145 277.498 1.00 22.93 ? 528 TRP B CZ3 1 ATOM 8206 C CH2 . TRP B 1 528 ? -60.663 -10.388 277.980 1.00 23.01 ? 528 TRP B CH2 1 ATOM 8207 N N . GLU B 1 529 ? -58.735 -6.699 283.181 1.00 20.52 ? 529 GLU B N 1 ATOM 8208 C CA . GLU B 1 529 ? -59.967 -6.215 282.571 1.00 18.58 ? 529 GLU B CA 1 ATOM 8209 C C . GLU B 1 529 ? -60.625 -5.205 283.508 1.00 25.11 ? 529 GLU B C 1 ATOM 8210 O O . GLU B 1 529 ? -60.341 -5.191 284.705 1.00 32.08 ? 529 GLU B O 1 ATOM 8211 C CB . GLU B 1 529 ? -60.904 -7.385 282.265 1.00 20.12 ? 529 GLU B CB 1 ATOM 8212 C CG . GLU B 1 529 ? -61.089 -8.348 283.430 1.00 22.36 ? 529 GLU B CG 1 ATOM 8213 C CD . GLU B 1 529 ? -61.809 -9.622 283.028 1.00 34.25 ? 529 GLU B CD 1 ATOM 8214 O OE1 . GLU B 1 529 ? -62.860 -9.934 283.625 1.00 20.67 ? 529 GLU B OE1 1 ATOM 8215 O OE2 . GLU B 1 529 ? -61.321 -10.313 282.110 1.00 60.81 ? 529 GLU B OE2 1 ATOM 8216 N N . ILE B 1 530 ? -61.510 -4.366 282.961 1.00 16.99 ? 530 ILE B N 1 ATOM 8217 C CA . ILE B 1 530 ? -62.011 -3.220 283.717 1.00 15.89 ? 530 ILE B CA 1 ATOM 8218 C C . ILE B 1 530 ? -62.844 -3.660 284.917 1.00 16.74 ? 530 ILE B C 1 ATOM 8219 O O . ILE B 1 530 ? -62.923 -2.941 285.921 1.00 24.08 ? 530 ILE B O 1 ATOM 8220 C CB . ILE B 1 530 ? -62.808 -2.280 282.792 1.00 14.32 ? 530 ILE B CB 1 ATOM 8221 C CG1 . ILE B 1 530 ? -63.104 -0.955 283.497 1.00 15.67 ? 530 ILE B CG1 1 ATOM 8222 C CG2 . ILE B 1 530 ? -64.105 -2.936 282.342 1.00 13.57 ? 530 ILE B CG2 1 ATOM 8223 C CD1 . ILE B 1 530 ? -61.877 -0.279 284.067 1.00 13.15 ? 530 ILE B CD1 1 ATOM 8224 N N . ASP B 1 531 ? -63.462 -4.838 284.851 1.00 16.51 ? 531 ASP B N 1 ATOM 8225 C CA . ASP B 1 531 ? -64.334 -5.282 285.931 1.00 16.90 ? 531 ASP B CA 1 ATOM 8226 C C . ASP B 1 531 ? -63.568 -5.778 287.149 1.00 19.60 ? 531 ASP B C 1 ATOM 8227 O O . ASP B 1 531 ? -64.151 -5.865 288.235 1.00 18.05 ? 531 ASP B O 1 ATOM 8228 C CB . ASP B 1 531 ? -65.264 -6.387 285.434 1.00 14.46 ? 531 ASP B CB 1 ATOM 8229 C CG . ASP B 1 531 ? -64.511 -7.570 284.878 1.00 13.68 ? 531 ASP B CG 1 ATOM 8230 O OD1 . ASP B 1 531 ? -64.128 -8.458 285.667 1.00 17.53 ? 531 ASP B OD1 1 ATOM 8231 O OD2 . ASP B 1 531 ? -64.297 -7.605 283.650 1.00 14.71 ? 531 ASP B OD2 1 ATOM 8232 N N . ALA B 1 532 ? -62.286 -6.101 287.000 1.00 22.94 ? 532 ALA B N 1 ATOM 8233 C CA . ALA B 1 532 ? -61.505 -6.666 288.091 1.00 25.30 ? 532 ALA B CA 1 ATOM 8234 C C . ALA B 1 532 ? -60.872 -5.612 288.990 1.00 25.26 ? 532 ALA B C 1 ATOM 8235 O O . ALA B 1 532 ? -60.337 -5.964 290.047 1.00 25.44 ? 532 ALA B O 1 ATOM 8236 C CB . ALA B 1 532 ? -60.412 -7.583 287.535 1.00 21.56 ? 532 ALA B CB 1 ATOM 8237 N N . ASP B 1 533 ? -60.920 -4.342 288.605 1.00 23.38 ? 533 ASP B N 1 ATOM 8238 C CA . ASP B 1 533 ? -60.333 -3.273 289.397 1.00 26.23 ? 533 ASP B CA 1 ATOM 8239 C C . ASP B 1 533 ? -61.329 -2.764 290.432 1.00 25.81 ? 533 ASP B C 1 ATOM 8240 O O . ASP B 1 533 ? -62.538 -2.719 290.191 1.00 55.44 ? 533 ASP B O 1 ATOM 8241 C CB . ASP B 1 533 ? -59.886 -2.120 288.496 1.00 26.28 ? 533 ASP B CB 1 ATOM 8242 C CG . ASP B 1 533 ? -59.308 -0.956 289.278 1.00 28.03 ? 533 ASP B CG 1 ATOM 8243 O OD1 . ASP B 1 533 ? -58.739 -1.189 290.364 1.00 30.43 ? 533 ASP B OD1 1 ATOM 8244 O OD2 . ASP B 1 533 ? -59.431 0.196 288.810 1.00 45.45 ? 533 ASP B OD2 1 ATOM 8245 N N . ASN B 1 534 ? -60.804 -2.385 291.598 1.00 22.09 ? 534 ASN B N 1 ATOM 8246 C CA . ASN B 1 534 ? -61.596 -1.750 292.641 1.00 22.27 ? 534 ASN B CA 1 ATOM 8247 C C . ASN B 1 534 ? -61.397 -0.239 292.673 1.00 25.93 ? 534 ASN B C 1 ATOM 8248 O O . ASN B 1 534 ? -61.720 0.405 293.676 1.00 41.56 ? 534 ASN B O 1 ATOM 8249 C CB . ASN B 1 534 ? -61.270 -2.362 294.006 1.00 24.69 ? 534 ASN B CB 1 ATOM 8250 C CG . ASN B 1 534 ? -59.916 -1.933 294.533 1.00 25.27 ? 534 ASN B CG 1 ATOM 8251 O OD1 . ASN B 1 534 ? -59.010 -1.607 293.766 1.00 25.79 ? 534 ASN B OD1 1 ATOM 8252 N ND2 . ASN B 1 534 ? -59.772 -1.928 295.853 1.00 23.49 ? 534 ASN B ND2 1 ATOM 8253 N N . GLY B 1 535 ? -60.869 0.337 291.592 1.00 25.46 ? 535 GLY B N 1 ATOM 8254 C CA . GLY B 1 535 ? -60.601 1.748 291.490 1.00 26.89 ? 535 GLY B CA 1 ATOM 8255 C C . GLY B 1 535 ? -59.149 2.121 291.717 1.00 26.56 ? 535 GLY B C 1 ATOM 8256 O O . GLY B 1 535 ? -58.704 3.163 291.224 1.00 49.99 ? 535 GLY B O 1 ATOM 8257 N N . ASP B 1 536 ? -58.400 1.289 292.443 1.00 24.04 ? 536 ASP B N 1 ATOM 8258 C CA . ASP B 1 536 ? -57.022 1.633 292.782 1.00 25.85 ? 536 ASP B CA 1 ATOM 8259 C C . ASP B 1 536 ? -56.137 1.696 291.544 1.00 26.03 ? 536 ASP B C 1 ATOM 8260 O O . ASP B 1 536 ? -55.313 2.608 291.410 1.00 26.17 ? 536 ASP B O 1 ATOM 8261 C CB . ASP B 1 536 ? -56.462 0.625 293.785 1.00 29.33 ? 536 ASP B CB 1 ATOM 8262 C CG . ASP B 1 536 ? -57.196 0.649 295.111 1.00 27.98 ? 536 ASP B CG 1 ATOM 8263 O OD1 . ASP B 1 536 ? -57.816 1.684 295.430 1.00 28.50 ? 536 ASP B OD1 1 ATOM 8264 O OD2 . ASP B 1 536 ? -57.151 -0.368 295.836 1.00 24.48 ? 536 ASP B OD2 1 ATOM 8265 N N . LEU B 1 537 ? -56.290 0.739 290.628 1.00 25.31 ? 537 LEU B N 1 ATOM 8266 C CA . LEU B 1 537 ? -55.386 0.667 289.485 1.00 27.00 ? 537 LEU B CA 1 ATOM 8267 C C . LEU B 1 537 ? -55.693 1.751 288.460 1.00 26.87 ? 537 LEU B C 1 ATOM 8268 O O . LEU B 1 537 ? -54.779 2.410 287.951 1.00 26.00 ? 537 LEU B O 1 ATOM 8269 C CB . LEU B 1 537 ? -55.459 -0.718 288.844 1.00 23.56 ? 537 LEU B CB 1 ATOM 8270 C CG . LEU B 1 537 ? -55.017 -1.872 289.744 1.00 26.58 ? 537 LEU B CG 1 ATOM 8271 C CD1 . LEU B 1 537 ? -54.913 -3.164 288.954 1.00 29.83 ? 537 LEU B CD1 1 ATOM 8272 C CD2 . LEU B 1 537 ? -53.692 -1.541 290.408 1.00 23.80 ? 537 LEU B CD2 1 ATOM 8273 N N . LEU B 1 538 ? -56.974 1.948 288.137 1.00 23.13 ? 538 LEU B N 1 ATOM 8274 C CA . LEU B 1 538 ? -57.322 2.904 287.091 1.00 23.54 ? 538 LEU B CA 1 ATOM 8275 C C . LEU B 1 538 ? -56.956 4.327 287.496 1.00 27.19 ? 538 LEU B C 1 ATOM 8276 O O . LEU B 1 538 ? -56.559 5.136 286.648 1.00 26.21 ? 538 LEU B O 1 ATOM 8277 C CB . LEU B 1 538 ? -58.809 2.802 286.754 1.00 21.93 ? 538 LEU B CB 1 ATOM 8278 C CG . LEU B 1 538 ? -59.243 3.667 285.570 1.00 21.40 ? 538 LEU B CG 1 ATOM 8279 C CD1 . LEU B 1 538 ? -58.317 3.439 284.385 1.00 26.55 ? 538 LEU B CD1 1 ATOM 8280 C CD2 . LEU B 1 538 ? -60.676 3.372 285.187 1.00 21.16 ? 538 LEU B CD2 1 ATOM 8281 N N . ASN B 1 539 ? -57.080 4.653 288.784 1.00 26.89 ? 539 ASN B N 1 ATOM 8282 C CA . ASN B 1 539 ? -56.606 5.949 289.257 1.00 24.93 ? 539 ASN B CA 1 ATOM 8283 C C . ASN B 1 539 ? -55.100 6.076 289.078 1.00 31.77 ? 539 ASN B C 1 ATOM 8284 O O . ASN B 1 539 ? -54.596 7.148 288.722 1.00 59.14 ? 539 ASN B O 1 ATOM 8285 C CB . ASN B 1 539 ? -56.990 6.151 290.723 1.00 23.30 ? 539 ASN B CB 1 ATOM 8286 C CG . ASN B 1 539 ? -58.488 6.159 290.937 1.00 24.28 ? 539 ASN B CG 1 ATOM 8287 O OD1 . ASN B 1 539 ? -59.262 6.023 289.990 1.00 25.17 ? 539 ASN B OD1 1 ATOM 8288 N ND2 . ASN B 1 539 ? -58.907 6.316 292.187 1.00 24.89 ? 539 ASN B ND2 1 ATOM 8289 N N . ALA B 1 540 ? -54.364 4.987 289.313 1.00 29.18 ? 540 ALA B N 1 ATOM 8290 C CA . ALA B 1 540 ? -52.918 5.016 289.124 1.00 28.31 ? 540 ALA B CA 1 ATOM 8291 C C . ALA B 1 540 ? -52.545 5.098 287.650 1.00 24.55 ? 540 ALA B C 1 ATOM 8292 O O . ALA B 1 540 ? -51.509 5.678 287.307 1.00 27.19 ? 540 ALA B O 1 ATOM 8293 C CB . ALA B 1 540 ? -52.280 3.785 289.766 1.00 33.63 ? 540 ALA B CB 1 ATOM 8294 N N . ILE B 1 541 ? -53.371 4.528 286.769 1.00 23.61 ? 541 ILE B N 1 ATOM 8295 C CA . ILE B 1 541 ? -53.091 4.586 285.336 1.00 27.76 ? 541 ILE B CA 1 ATOM 8296 C C . ILE B 1 541 ? -53.120 6.028 284.845 1.00 27.11 ? 541 ILE B C 1 ATOM 8297 O O . ILE B 1 541 ? -52.315 6.428 283.995 1.00 25.82 ? 541 ILE B O 1 ATOM 8298 C CB . ILE B 1 541 ? -54.088 3.702 284.563 1.00 26.22 ? 541 ILE B CB 1 ATOM 8299 C CG1 . ILE B 1 541 ? -53.889 2.228 284.920 1.00 24.47 ? 541 ILE B CG1 1 ATOM 8300 C CG2 . ILE B 1 541 ? -53.949 3.907 283.063 1.00 27.97 ? 541 ILE B CG2 1 ATOM 8301 C CD1 . ILE B 1 541 ? -54.867 1.300 284.239 1.00 25.12 ? 541 ILE B CD1 1 ATOM 8302 N N . ASN B 1 542 ? -54.035 6.834 285.381 1.00 23.82 ? 542 ASN B N 1 ATOM 8303 C CA . ASN B 1 542 ? -54.224 8.208 284.940 1.00 28.52 ? 542 ASN B CA 1 ATOM 8304 C C . ASN B 1 542 ? -53.435 9.212 285.774 1.00 32.62 ? 542 ASN B C 1 ATOM 8305 O O . ASN B 1 542 ? -53.743 10.409 285.735 1.00 47.18 ? 542 ASN B O 1 ATOM 8306 C CB . ASN B 1 542 ? -55.712 8.563 284.963 1.00 29.36 ? 542 ASN B CB 1 ATOM 8307 C CG . ASN B 1 542 ? -56.522 7.734 283.988 1.00 31.65 ? 542 ASN B CG 1 ATOM 8308 O OD1 . ASN B 1 542 ? -56.658 8.087 282.818 1.00 29.40 ? 542 ASN B OD1 1 ATOM 8309 N ND2 . ASN B 1 542 ? -57.063 6.619 284.467 1.00 36.77 ? 542 ASN B ND2 1 ATOM 8310 N N . ALA B 1 543 ? -52.432 8.758 286.521 1.00 32.96 ? 543 ALA B N 1 ATOM 8311 C CA . ALA B 1 543 ? -51.651 9.664 287.353 1.00 34.73 ? 543 ALA B CA 1 ATOM 8312 C C . ALA B 1 543 ? -50.830 10.607 286.483 1.00 34.53 ? 543 ALA B C 1 ATOM 8313 O O . ALA B 1 543 ? -50.096 10.169 285.592 1.00 31.40 ? 543 ALA B O 1 ATOM 8314 C CB . ALA B 1 543 ? -50.740 8.873 288.289 1.00 48.72 ? 543 ALA B CB 1 ATOM 8315 N N . GLN B 1 544 ? -50.954 11.905 286.746 1.00 39.56 ? 544 GLN B N 1 ATOM 8316 C CA . GLN B 1 544 ? -50.288 12.937 285.964 1.00 42.80 ? 544 GLN B CA 1 ATOM 8317 C C . GLN B 1 544 ? -48.994 13.345 286.657 1.00 48.72 ? 544 GLN B C 1 ATOM 8318 O O . GLN B 1 544 ? -49.011 13.744 287.827 1.00 48.92 ? 544 GLN B O 1 ATOM 8319 C CB . GLN B 1 544 ? -51.202 14.149 285.778 1.00 39.23 ? 544 GLN B CB 1 ATOM 8320 C CG . GLN B 1 544 ? -50.675 15.184 284.798 1.00 41.39 ? 544 GLN B CG 1 ATOM 8321 C CD . GLN B 1 544 ? -50.487 14.625 283.401 1.00 43.75 ? 544 GLN B CD 1 ATOM 8322 O OE1 . GLN B 1 544 ? -51.456 14.333 282.702 1.00 40.12 ? 544 GLN B OE1 1 ATOM 8323 N NE2 . GLN B 1 544 ? -49.234 14.473 282.988 1.00 49.34 ? 544 GLN B NE2 1 ATOM 8324 N N . PHE B 1 545 ? -47.882 13.244 285.937 1.00 47.19 ? 545 PHE B N 1 ATOM 8325 C CA . PHE B 1 545 ? -46.592 13.694 286.447 1.00 49.51 ? 545 PHE B CA 1 ATOM 8326 C C . PHE B 1 545 ? -46.144 14.964 285.730 1.00 45.84 ? 545 PHE B C 1 ATOM 8327 O O . PHE B 1 545 ? -45.707 15.924 286.364 1.00 47.77 ? 545 PHE B O 1 ATOM 8328 C CB . PHE B 1 545 ? -45.532 12.601 286.290 1.00 58.23 ? 545 PHE B CB 1 ATOM 8329 C CG . PHE B 1 545 ? -45.714 11.437 287.223 1.00 46.34 ? 545 PHE B CG 1 ATOM 8330 C CD1 . PHE B 1 545 ? -45.313 11.526 288.546 1.00 39.57 ? 545 PHE B CD1 1 ATOM 8331 C CD2 . PHE B 1 545 ? -46.276 10.253 286.777 1.00 42.39 ? 545 PHE B CD2 1 ATOM 8332 C CE1 . PHE B 1 545 ? -45.475 10.458 289.408 1.00 40.24 ? 545 PHE B CE1 1 ATOM 8333 C CE2 . PHE B 1 545 ? -46.440 9.182 287.635 1.00 36.12 ? 545 PHE B CE2 1 ATOM 8334 C CZ . PHE B 1 545 ? -46.039 9.285 288.952 1.00 38.83 ? 545 PHE B CZ 1 HETATM 8335 C C1 . NAG C 2 . ? -93.459 23.303 277.107 1.00 48.77 ? 601 NAG A C1 1 HETATM 8336 C C2 . NAG C 2 . ? -94.600 22.804 277.989 1.00 42.17 ? 601 NAG A C2 1 HETATM 8337 C C3 . NAG C 2 . ? -95.888 22.697 277.177 1.00 47.02 ? 601 NAG A C3 1 HETATM 8338 C C4 . NAG C 2 . ? -96.186 24.015 276.474 1.00 62.06 ? 601 NAG A C4 1 HETATM 8339 C C5 . NAG C 2 . ? -94.977 24.463 275.659 1.00 53.96 ? 601 NAG A C5 1 HETATM 8340 C C6 . NAG C 2 . ? -95.158 25.825 275.030 1.00 45.52 ? 601 NAG A C6 1 HETATM 8341 C C7 . NAG C 2 . ? -93.997 21.371 279.893 1.00 51.37 ? 601 NAG A C7 1 HETATM 8342 C C8 . NAG C 2 . ? -94.048 22.616 280.726 1.00 40.62 ? 601 NAG A C8 1 HETATM 8343 N N2 . NAG C 2 . ? -94.270 21.522 278.592 1.00 42.30 ? 601 NAG A N2 1 HETATM 8344 O O1 . NAG C 2 . ? -92.314 23.456 277.881 1.00 47.61 ? 601 NAG A O1 1 HETATM 8345 O O3 . NAG C 2 . ? -96.964 22.353 278.042 1.00 56.85 ? 601 NAG A O3 1 HETATM 8346 O O4 . NAG C 2 . ? -97.304 23.861 275.607 1.00 72.04 ? 601 NAG A O4 1 HETATM 8347 O O5 . NAG C 2 . ? -93.823 24.549 276.509 1.00 70.18 ? 601 NAG A O5 1 HETATM 8348 O O6 . NAG C 2 . ? -94.028 26.657 275.256 1.00 42.03 ? 601 NAG A O6 1 HETATM 8349 O O7 . NAG C 2 . ? -93.720 20.277 280.375 1.00 61.47 ? 601 NAG A O7 1 HETATM 8350 C C1 . NAG D 2 . ? -70.307 13.482 288.158 1.00 68.92 ? 602 NAG A C1 1 HETATM 8351 C C2 . NAG D 2 . ? -70.577 14.971 287.944 1.00 56.89 ? 602 NAG A C2 1 HETATM 8352 C C3 . NAG D 2 . ? -71.290 15.194 286.613 1.00 54.95 ? 602 NAG A C3 1 HETATM 8353 C C4 . NAG D 2 . ? -70.503 14.554 285.478 1.00 54.38 ? 602 NAG A C4 1 HETATM 8354 C C5 . NAG D 2 . ? -70.227 13.084 285.787 1.00 66.33 ? 602 NAG A C5 1 HETATM 8355 C C6 . NAG D 2 . ? -69.335 12.425 284.761 1.00 80.62 ? 602 NAG A C6 1 HETATM 8356 C C7 . NAG D 2 . ? -72.564 15.163 289.410 1.00 89.28 ? 602 NAG A C7 1 HETATM 8357 C C8 . NAG D 2 . ? -73.160 15.897 290.573 1.00 61.70 ? 602 NAG A C8 1 HETATM 8358 N N2 . NAG D 2 . ? -71.333 15.549 289.046 1.00 73.72 ? 602 NAG A N2 1 HETATM 8359 O O1 . NAG D 2 . ? -69.603 13.307 289.344 1.00 83.00 ? 602 NAG A O1 1 HETATM 8360 O O3 . NAG D 2 . ? -71.436 16.590 286.378 1.00 51.68 ? 602 NAG A O3 1 HETATM 8361 O O4 . NAG D 2 . ? -71.237 14.648 284.262 1.00 52.01 ? 602 NAG A O4 1 HETATM 8362 O O5 . NAG D 2 . ? -69.559 12.964 287.053 1.00 72.09 ? 602 NAG A O5 1 HETATM 8363 O O6 . NAG D 2 . ? -68.470 13.367 284.142 1.00 56.02 ? 602 NAG A O6 1 HETATM 8364 O O7 . NAG D 2 . ? -73.170 14.265 288.830 1.00 98.73 ? 602 NAG A O7 1 HETATM 8365 C C1 . NAG E 2 . ? -116.524 15.652 305.846 1.00 41.99 ? 603 NAG A C1 1 HETATM 8366 C C2 . NAG E 2 . ? -115.449 14.580 306.020 1.00 42.91 ? 603 NAG A C2 1 HETATM 8367 C C3 . NAG E 2 . ? -114.326 14.786 305.006 1.00 39.23 ? 603 NAG A C3 1 HETATM 8368 C C4 . NAG E 2 . ? -114.890 14.877 303.594 1.00 37.83 ? 603 NAG A C4 1 HETATM 8369 C C5 . NAG E 2 . ? -115.982 15.940 303.531 1.00 37.95 ? 603 NAG A C5 1 HETATM 8370 C C6 . NAG E 2 . ? -116.666 16.008 302.186 1.00 37.90 ? 603 NAG A C6 1 HETATM 8371 C C7 . NAG E 2 . ? -114.370 13.520 307.955 1.00 71.89 ? 603 NAG A C7 1 HETATM 8372 C C8 . NAG E 2 . ? -113.880 13.712 309.358 1.00 60.16 ? 603 NAG A C8 1 HETATM 8373 N N2 . NAG E 2 . ? -114.923 14.590 307.375 1.00 73.88 ? 603 NAG A N2 1 HETATM 8374 O O1 . NAG E 2 . ? -117.571 15.401 306.726 1.00 39.89 ? 603 NAG A O1 1 HETATM 8375 O O3 . NAG E 2 . ? -113.406 13.704 305.089 1.00 40.46 ? 603 NAG A O3 1 HETATM 8376 O O4 . NAG E 2 . ? -113.856 15.207 302.674 1.00 40.63 ? 603 NAG A O4 1 HETATM 8377 O O5 . NAG E 2 . ? -116.999 15.646 304.499 1.00 41.89 ? 603 NAG A O5 1 HETATM 8378 O O6 . NAG E 2 . ? -117.418 17.205 302.044 1.00 38.88 ? 603 NAG A O6 1 HETATM 8379 O O7 . NAG E 2 . ? -114.268 12.445 307.372 1.00 77.74 ? 603 NAG A O7 1 HETATM 8380 C C1 . SN5 F 3 . ? -110.349 14.643 302.046 1.00 34.17 ? 604 SN5 A C1 1 HETATM 8381 S S7 . SN5 F 3 . ? -110.032 10.800 300.726 1.00 29.43 ? 604 SN5 A S7 1 HETATM 8382 C C2 . SN5 F 3 . ? -109.689 13.360 302.395 1.00 35.39 ? 604 SN5 A C2 1 HETATM 8383 C C3 . SN5 F 3 . ? -108.765 13.483 303.515 1.00 32.24 ? 604 SN5 A C3 1 HETATM 8384 C C4 . SN5 F 3 . ? -107.766 14.554 303.304 1.00 37.72 ? 604 SN5 A C4 1 HETATM 8385 C C5 . SN5 F 3 . ? -108.439 15.913 303.046 1.00 36.36 ? 604 SN5 A C5 1 HETATM 8386 C C6 . SN5 F 3 . ? -107.461 16.894 302.736 1.00 30.97 ? 604 SN5 A C6 1 HETATM 8387 C C7 . SN5 F 3 . ? -110.791 11.031 302.123 1.00 40.31 ? 604 SN5 A C7 1 HETATM 8388 C C8 . SN5 F 3 . ? -111.535 9.885 302.781 1.00 41.72 ? 604 SN5 A C8 1 HETATM 8389 N N2 . SN5 F 3 . ? -110.767 12.346 302.767 1.00 41.17 ? 604 SN5 A N2 1 HETATM 8390 O O3 . SN5 F 3 . ? -108.046 12.189 303.702 1.00 35.93 ? 604 SN5 A O3 1 HETATM 8391 O O4 . SN5 F 3 . ? -106.924 14.653 304.477 1.00 72.23 ? 604 SN5 A O4 1 HETATM 8392 O O5 . SN5 F 3 . ? -109.389 15.725 301.849 1.00 37.79 ? 604 SN5 A O5 1 HETATM 8393 O O6 . SN5 F 3 . ? -108.085 18.101 302.462 1.00 31.12 ? 604 SN5 A O6 1 HETATM 8394 C C1 . 58Y G 4 . ? -113.285 16.376 298.222 1.00 24.11 ? 605 58Y A C1 1 HETATM 8395 C C2 . 58Y G 4 . ? -112.293 17.148 298.891 1.00 24.99 ? 605 58Y A C2 1 HETATM 8396 C C3 . 58Y G 4 . ? -111.090 16.362 299.192 1.00 28.26 ? 605 58Y A C3 1 HETATM 8397 C C4 . 58Y G 4 . ? -111.349 14.990 299.827 1.00 29.53 ? 605 58Y A C4 1 HETATM 8398 C C5 . 58Y G 4 . ? -112.559 14.240 299.251 1.00 29.98 ? 605 58Y A C5 1 HETATM 8399 C C6 . 58Y G 4 . ? -112.978 13.091 300.223 1.00 30.26 ? 605 58Y A C6 1 HETATM 8400 C C7 . 58Y G 4 . ? -112.121 17.732 296.463 1.00 21.55 ? 605 58Y A C7 1 HETATM 8401 C C8 . 58Y G 4 . ? -110.902 17.673 295.512 1.00 19.23 ? 605 58Y A C8 1 HETATM 8402 N N2 . 58Y G 4 . ? -111.718 18.206 297.781 1.00 23.74 ? 605 58Y A N2 1 HETATM 8403 S S1 . 58Y G 4 . ? -112.723 16.252 296.709 1.00 29.14 ? 605 58Y A S1 1 HETATM 8404 O O3 . 58Y G 4 . ? -110.259 17.143 300.082 1.00 40.19 ? 605 58Y A O3 1 HETATM 8405 O O4 . 58Y G 4 . ? -111.449 15.109 301.234 1.00 30.81 ? 605 58Y A O4 1 HETATM 8406 O O5 . 58Y G 4 . ? -113.635 15.005 299.047 1.00 26.00 ? 605 58Y A O5 1 HETATM 8407 O O6 . 58Y G 4 . ? -114.273 13.382 300.698 1.00 30.67 ? 605 58Y A O6 1 HETATM 8408 CL CL . CL H 5 . ? -75.166 28.864 288.505 1.00 20.29 ? 606 CL A CL 1 HETATM 8409 S S . SO4 I 6 . ? -87.971 33.442 288.377 1.00 72.14 ? 607 SO4 A S 1 HETATM 8410 O O1 . SO4 I 6 . ? -87.978 32.017 288.694 1.00 42.86 ? 607 SO4 A O1 1 HETATM 8411 O O2 . SO4 I 6 . ? -88.151 33.621 286.939 1.00 66.73 ? 607 SO4 A O2 1 HETATM 8412 O O3 . SO4 I 6 . ? -86.694 34.023 288.781 1.00 59.57 ? 607 SO4 A O3 1 HETATM 8413 O O4 . SO4 I 6 . ? -89.057 34.106 289.091 1.00 41.16 ? 607 SO4 A O4 1 HETATM 8414 S S . SO4 J 6 . ? -92.202 34.679 296.856 1.00 39.07 ? 608 SO4 A S 1 HETATM 8415 O O1 . SO4 J 6 . ? -90.818 34.527 296.417 1.00 38.37 ? 608 SO4 A O1 1 HETATM 8416 O O2 . SO4 J 6 . ? -92.968 35.382 295.831 1.00 50.07 ? 608 SO4 A O2 1 HETATM 8417 O O3 . SO4 J 6 . ? -92.786 33.361 297.077 1.00 40.20 ? 608 SO4 A O3 1 HETATM 8418 O O4 . SO4 J 6 . ? -92.238 35.443 298.099 1.00 59.96 ? 608 SO4 A O4 1 HETATM 8419 S S . SO4 K 6 . ? -65.739 34.909 280.704 1.00 41.85 ? 609 SO4 A S 1 HETATM 8420 O O1 . SO4 K 6 . ? -66.141 33.796 279.849 1.00 32.69 ? 609 SO4 A O1 1 HETATM 8421 O O2 . SO4 K 6 . ? -65.734 36.143 279.925 1.00 48.98 ? 609 SO4 A O2 1 HETATM 8422 O O3 . SO4 K 6 . ? -66.680 35.036 281.812 1.00 42.70 ? 609 SO4 A O3 1 HETATM 8423 O O4 . SO4 K 6 . ? -64.401 34.661 281.230 1.00 44.02 ? 609 SO4 A O4 1 HETATM 8424 C C1 . NAG L 2 . ? -52.815 -19.015 278.614 1.00 60.90 ? 601 NAG B C1 1 HETATM 8425 C C2 . NAG L 2 . ? -53.971 -19.125 279.607 1.00 37.10 ? 601 NAG B C2 1 HETATM 8426 C C3 . NAG L 2 . ? -55.106 -18.185 279.209 1.00 34.41 ? 601 NAG B C3 1 HETATM 8427 C C4 . NAG L 2 . ? -54.586 -16.767 279.017 1.00 33.29 ? 601 NAG B C4 1 HETATM 8428 C C5 . NAG L 2 . ? -53.411 -16.765 278.044 1.00 42.51 ? 601 NAG B C5 1 HETATM 8429 C C6 . NAG L 2 . ? -52.770 -15.406 277.890 1.00 34.73 ? 601 NAG B C6 1 HETATM 8430 C C7 . NAG L 2 . ? -54.452 -21.199 280.830 1.00 38.25 ? 601 NAG B C7 1 HETATM 8431 C C8 . NAG L 2 . ? -54.981 -22.598 280.735 1.00 41.84 ? 601 NAG B C8 1 HETATM 8432 N N2 . NAG L 2 . ? -54.450 -20.495 279.694 1.00 36.16 ? 601 NAG B N2 1 HETATM 8433 O O1 . NAG L 2 . ? -51.764 -19.817 279.041 1.00 42.08 ? 601 NAG B O1 1 HETATM 8434 O O3 . NAG L 2 . ? -56.108 -18.200 280.219 1.00 33.01 ? 601 NAG B O3 1 HETATM 8435 O O4 . NAG L 2 . ? -55.620 -15.933 278.507 1.00 33.94 ? 601 NAG B O4 1 HETATM 8436 O O5 . NAG L 2 . ? -52.390 -17.654 278.519 1.00 60.04 ? 601 NAG B O5 1 HETATM 8437 O O6 . NAG L 2 . ? -53.146 -14.789 276.666 1.00 37.41 ? 601 NAG B O6 1 HETATM 8438 O O7 . NAG L 2 . ? -54.046 -20.728 281.888 1.00 57.62 ? 601 NAG B O7 1 HETATM 8439 C C1 . NAG M 2 . ? -39.581 -19.300 277.232 1.00 54.95 ? 602 NAG B C1 1 HETATM 8440 C C2 . NAG M 2 . ? -38.470 -18.249 277.249 1.00 59.02 ? 602 NAG B C2 1 HETATM 8441 C C3 . NAG M 2 . ? -38.249 -17.731 278.669 1.00 52.17 ? 602 NAG B C3 1 HETATM 8442 C C4 . NAG M 2 . ? -39.563 -17.261 279.278 1.00 44.89 ? 602 NAG B C4 1 HETATM 8443 C C5 . NAG M 2 . ? -40.611 -18.364 279.179 1.00 46.26 ? 602 NAG B C5 1 HETATM 8444 C C6 . NAG M 2 . ? -41.973 -17.934 279.670 1.00 47.00 ? 602 NAG B C6 1 HETATM 8445 C C7 . NAG M 2 . ? -36.272 -18.039 276.170 1.00 77.22 ? 602 NAG B C7 1 HETATM 8446 C C8 . NAG M 2 . ? -35.069 -18.773 275.660 1.00 62.64 ? 602 NAG B C8 1 HETATM 8447 N N2 . NAG M 2 . ? -37.236 -18.795 276.707 1.00 89.59 ? 602 NAG B N2 1 HETATM 8448 O O1 . NAG M 2 . ? -39.825 -19.690 275.920 1.00 52.21 ? 602 NAG B O1 1 HETATM 8449 O O3 . NAG M 2 . ? -37.318 -16.655 278.645 1.00 68.19 ? 602 NAG B O3 1 HETATM 8450 O O4 . NAG M 2 . ? -39.369 -16.915 280.645 1.00 48.46 ? 602 NAG B O4 1 HETATM 8451 O O5 . NAG M 2 . ? -40.768 -18.755 277.808 1.00 62.86 ? 602 NAG B O5 1 HETATM 8452 O O6 . NAG M 2 . ? -42.317 -18.588 280.884 1.00 47.25 ? 602 NAG B O6 1 HETATM 8453 O O7 . NAG M 2 . ? -36.368 -16.818 276.097 1.00 63.24 ? 602 NAG B O7 1 HETATM 8454 C C1 . NAG N 2 . ? -35.826 -29.169 295.574 1.00 53.24 ? 603 NAG B C1 1 HETATM 8455 C C2 . NAG N 2 . ? -35.760 -28.875 294.075 1.00 38.51 ? 603 NAG B C2 1 HETATM 8456 C C3 . NAG N 2 . ? -34.535 -29.543 293.455 1.00 44.11 ? 603 NAG B C3 1 HETATM 8457 C C4 . NAG N 2 . ? -33.271 -29.141 294.203 1.00 37.61 ? 603 NAG B C4 1 HETATM 8458 C C5 . NAG N 2 . ? -33.426 -29.451 295.687 1.00 36.14 ? 603 NAG B C5 1 HETATM 8459 C C6 . NAG N 2 . ? -32.255 -28.979 296.515 1.00 38.24 ? 603 NAG B C6 1 HETATM 8460 C C7 . NAG N 2 . ? -37.476 -28.717 292.325 1.00 40.43 ? 603 NAG B C7 1 HETATM 8461 C C8 . NAG N 2 . ? -38.732 -29.314 291.767 1.00 42.29 ? 603 NAG B C8 1 HETATM 8462 N N2 . NAG N 2 . ? -36.973 -29.319 293.407 1.00 39.09 ? 603 NAG B N2 1 HETATM 8463 O O3 . NAG N 2 . ? -34.428 -29.169 292.086 1.00 52.64 ? 603 NAG B O3 1 HETATM 8464 O O4 . NAG N 2 . ? -32.153 -29.853 293.688 1.00 38.64 ? 603 NAG B O4 1 HETATM 8465 O O5 . NAG N 2 . ? -34.587 -28.783 296.201 1.00 38.65 ? 603 NAG B O5 1 HETATM 8466 O O6 . NAG N 2 . ? -32.686 -28.422 297.749 1.00 44.06 ? 603 NAG B O6 1 HETATM 8467 O O7 . NAG N 2 . ? -36.941 -27.736 291.820 1.00 43.52 ? 603 NAG B O7 1 HETATM 8468 C C1 . SN5 O 3 . ? -58.785 -14.981 278.521 1.00 34.17 ? 604 SN5 B C1 1 HETATM 8469 S S7 . SN5 O 3 . ? -59.386 -13.372 282.217 1.00 29.43 ? 604 SN5 B S7 1 HETATM 8470 C C2 . SN5 O 3 . ? -59.590 -15.196 279.750 1.00 35.39 ? 604 SN5 B C2 1 HETATM 8471 C C3 . SN5 O 3 . ? -60.571 -16.264 279.607 1.00 32.24 ? 604 SN5 B C3 1 HETATM 8472 C C4 . SN5 O 3 . ? -61.444 -16.070 278.428 1.00 37.72 ? 604 SN5 B C4 1 HETATM 8473 C C5 . SN5 O 3 . ? -60.626 -15.951 277.131 1.00 36.36 ? 604 SN5 B C5 1 HETATM 8474 C C6 . SN5 O 3 . ? -61.480 -15.654 276.037 1.00 30.97 ? 604 SN5 B C6 1 HETATM 8475 C C7 . SN5 O 3 . ? -58.704 -14.825 282.157 1.00 40.31 ? 604 SN5 B C7 1 HETATM 8476 C C8 . SN5 O 3 . ? -58.122 -15.443 283.413 1.00 41.72 ? 604 SN5 B C8 1 HETATM 8477 N N2 . SN5 O 3 . ? -58.643 -15.559 280.891 1.00 41.17 ? 604 SN5 B N2 1 HETATM 8478 O O3 . SN5 O 3 . ? -61.424 -16.313 280.830 1.00 35.93 ? 604 SN5 B O3 1 HETATM 8479 O O4 . SN5 O 3 . ? -62.350 -17.193 278.320 1.00 72.23 ? 604 SN5 B O4 1 HETATM 8480 O O5 . SN5 O 3 . ? -59.619 -14.804 277.336 1.00 37.79 ? 604 SN5 B O5 1 HETATM 8481 O O6 . SN5 O 3 . ? -60.724 -15.506 274.885 1.00 31.12 ? 604 SN5 B O6 1 HETATM 8482 C C1 . 58Y P 4 . ? -55.441 -11.478 276.850 1.00 24.11 ? 605 58Y B C1 1 HETATM 8483 C C2 . 58Y P 4 . ? -56.396 -12.139 276.027 1.00 24.99 ? 605 58Y B C2 1 HETATM 8484 C C3 . 58Y P 4 . ? -57.688 -12.309 276.704 1.00 28.26 ? 605 58Y B C3 1 HETATM 8485 C C4 . 58Y P 4 . ? -57.608 -12.858 278.134 1.00 29.53 ? 605 58Y B C4 1 HETATM 8486 C C5 . 58Y P 4 . ? -56.440 -12.305 278.964 1.00 29.98 ? 605 58Y B C5 1 HETATM 8487 C C6 . 58Y P 4 . ? -56.203 -13.215 280.211 1.00 30.26 ? 605 58Y B C6 1 HETATM 8488 C C7 . 58Y P 4 . ? -56.345 -9.753 275.271 1.00 21.55 ? 605 58Y B C7 1 HETATM 8489 C C8 . 58Y P 4 . ? -57.496 -8.728 275.142 1.00 19.23 ? 605 58Y B C8 1 HETATM 8490 N N2 . 58Y P 4 . ? -56.788 -11.075 274.845 1.00 23.74 ? 605 58Y B N2 1 HETATM 8491 S S1 . 58Y P 4 . ? -55.908 -9.929 276.817 1.00 29.14 ? 605 58Y B S1 1 HETATM 8492 O O3 . 58Y P 4 . ? -58.497 -13.200 275.902 1.00 40.19 ? 605 58Y B O3 1 HETATM 8493 O O4 . 58Y P 4 . ? -57.592 -14.274 278.118 1.00 30.81 ? 605 58Y B O4 1 HETATM 8494 O O5 . 58Y P 4 . ? -55.283 -12.222 278.301 1.00 26.00 ? 605 58Y B O5 1 HETATM 8495 O O6 . 58Y P 4 . ? -54.921 -13.788 280.085 1.00 30.67 ? 605 58Y B O6 1 HETATM 8496 S S . SO4 Q 6 . ? -69.238 -5.017 292.714 1.00 72.46 ? 606 SO4 B S 1 HETATM 8497 O O1 . SO4 Q 6 . ? -68.234 -5.034 291.654 1.00 49.59 ? 606 SO4 B O1 1 HETATM 8498 O O2 . SO4 Q 6 . ? -70.570 -5.092 292.120 1.00 63.28 ? 606 SO4 B O2 1 HETATM 8499 O O3 . SO4 Q 6 . ? -69.035 -6.160 293.598 1.00 58.73 ? 606 SO4 B O3 1 HETATM 8500 O O4 . SO4 Q 6 . ? -69.113 -3.781 293.480 1.00 54.42 ? 606 SO4 B O4 1 HETATM 8501 S S . SO4 R 6 . ? -74.423 -9.362 256.633 1.00 51.69 ? 607 SO4 B S 1 HETATM 8502 O O1 . SO4 R 6 . ? -73.398 -8.980 255.667 1.00 44.74 ? 607 SO4 B O1 1 HETATM 8503 O O2 . SO4 R 6 . ? -75.426 -10.195 255.976 1.00 44.55 ? 607 SO4 B O2 1 HETATM 8504 O O3 . SO4 R 6 . ? -73.807 -10.110 257.723 1.00 44.32 ? 607 SO4 B O3 1 HETATM 8505 O O4 . SO4 R 6 . ? -75.063 -8.163 257.167 1.00 61.44 ? 607 SO4 B O4 1 HETATM 8506 O O . HOH S 7 . ? -90.610 7.735 302.940 1.00 14.74 ? 701 HOH A O 1 HETATM 8507 O O . HOH S 7 . ? -128.915 28.225 292.534 1.00 21.38 ? 702 HOH A O 1 HETATM 8508 O O . HOH S 7 . ? -93.982 -0.761 295.379 1.00 12.16 ? 703 HOH A O 1 HETATM 8509 O O . HOH S 7 . ? -85.022 4.399 288.636 1.00 13.29 ? 704 HOH A O 1 HETATM 8510 O O . HOH T 7 . ? -61.413 1.135 287.922 1.00 26.87 ? 701 HOH B O 1 HETATM 8511 O O . HOH T 7 . ? -41.576 -12.028 283.614 1.00 25.14 ? 702 HOH B O 1 HETATM 8512 O O . HOH T 7 . ? -83.203 -18.292 266.010 1.00 21.33 ? 703 HOH B O 1 HETATM 8513 O O . HOH T 7 . ? -51.469 -1.436 295.485 1.00 19.02 ? 704 HOH B O 1 HETATM 8514 O O . HOH T 7 . ? -83.910 1.528 284.653 1.00 27.81 ? 705 HOH B O 1 HETATM 8515 O O . HOH T 7 . ? -39.636 12.072 285.273 1.00 18.00 ? 706 HOH B O 1 HETATM 8516 O O . HOH T 7 . ? -36.433 3.204 280.311 1.00 32.72 ? 707 HOH B O 1 HETATM 8517 O O . HOH T 7 . ? -85.827 2.156 282.921 1.00 33.51 ? 708 HOH B O 1 HETATM 8518 O O . HOH T 7 . ? -56.558 4.774 263.254 1.00 28.77 ? 709 HOH B O 1 HETATM 8519 O O . HOH T 7 . ? -57.791 -27.573 262.652 1.00 17.83 ? 710 HOH B O 1 HETATM 8520 O O . HOH T 7 . ? -35.071 -5.238 273.153 1.00 39.66 ? 711 HOH B O 1 HETATM 8521 O O . HOH T 7 . ? -65.173 -1.578 249.816 1.00 21.49 ? 712 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 MET 1 1 ? ? ? A . n A 1 2 LEU 2 2 ? ? ? A . n A 1 3 TYR 3 3 ? ? ? A . n A 1 4 LYS 4 4 ? ? ? A . n A 1 5 LEU 5 5 ? ? ? A . n A 1 6 LEU 6 6 ? ? ? A . n A 1 7 ASN 7 7 ? ? ? A . n A 1 8 VAL 8 8 ? ? ? A . n A 1 9 LEU 9 9 ? ? ? A . n A 1 10 TRP 10 10 ? ? ? A . n A 1 11 LEU 11 11 ? ? ? A . n A 1 12 VAL 12 12 ? ? ? A . n A 1 13 ALA 13 13 ? ? ? A . n A 1 14 VAL 14 14 ? ? ? A . n A 1 15 SER 15 15 ? ? ? A . n A 1 16 ASN 16 16 ? ? ? A . n A 1 17 ALA 17 17 ? ? ? A . n A 1 18 ILE 18 18 18 ILE ILE A . n A 1 19 PRO 19 19 19 PRO PRO A . n A 1 20 GLY 20 20 20 GLY GLY A . n A 1 21 THR 21 21 21 THR THR A . n A 1 22 PRO 22 22 22 PRO PRO A . n A 1 23 VAL 23 23 23 VAL VAL A . n A 1 24 ILE 24 24 24 ILE ILE A . n A 1 25 ASP 25 25 25 ASP ASP A . n A 1 26 TRP 26 26 26 TRP TRP A . n A 1 27 ALA 27 27 27 ALA ALA A . n A 1 28 ASP 28 28 28 ASP ASP A . n A 1 29 ARG 29 29 29 ARG ARG A . n A 1 30 ASN 30 30 30 ASN ASN A . n A 1 31 TYR 31 31 31 TYR TYR A . n A 1 32 ALA 32 32 32 ALA ALA A . n A 1 33 LEU 33 33 33 LEU LEU A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 GLU 35 35 35 GLU GLU A . n A 1 36 ILE 36 36 36 ILE ILE A . n A 1 37 ASN 37 37 37 ASN ASN A . n A 1 38 TYR 38 38 38 TYR TYR A . n A 1 39 GLU 39 39 39 GLU GLU A . n A 1 40 ALA 40 40 40 ALA ALA A . n A 1 41 THR 41 41 41 THR THR A . n A 1 42 ALA 42 42 42 ALA ALA A . n A 1 43 TYR 43 43 43 TYR TYR A . n A 1 44 GLU 44 44 44 GLU GLU A . n A 1 45 ASN 45 45 45 ASN ASN A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 ILE 47 47 47 ILE ILE A . n A 1 48 LYS 48 48 48 LYS LYS A . n A 1 49 PRO 49 49 49 PRO PRO A . n A 1 50 LYS 50 50 50 LYS LYS A . n A 1 51 GLU 51 51 51 GLU GLU A . n A 1 52 GLN 52 52 52 GLN GLN A . n A 1 53 VAL 53 53 53 VAL VAL A . n A 1 54 ASP 54 54 54 ASP ASP A . n A 1 55 VAL 55 55 55 VAL VAL A . n A 1 56 GLN 56 56 56 GLN GLN A . n A 1 57 VAL 57 57 57 VAL VAL A . n A 1 58 SER 58 58 58 SER SER A . n A 1 59 TRP 59 59 59 TRP TRP A . n A 1 60 ASN 60 60 60 ASN ASN A . n A 1 61 VAL 61 61 61 VAL VAL A . n A 1 62 TRP 62 62 62 TRP TRP A . n A 1 63 ASN 63 63 63 ASN ASN A . n A 1 64 GLY 64 64 64 GLY GLY A . n A 1 65 ASP 65 65 65 ASP ASP A . n A 1 66 ILE 66 66 66 ILE ILE A . n A 1 67 GLY 67 67 67 GLY GLY A . n A 1 68 ASP 68 68 68 ASP ASP A . n A 1 69 ILE 69 69 69 ILE ILE A . n A 1 70 ALA 70 70 70 ALA ALA A . n A 1 71 TYR 71 71 71 TYR TYR A . n A 1 72 VAL 72 72 72 VAL VAL A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 PHE 74 74 74 PHE PHE A . n A 1 75 ASP 75 75 75 ASP ASP A . n A 1 76 GLU 76 76 76 GLU GLU A . n A 1 77 GLN 77 77 77 GLN GLN A . n A 1 78 GLN 78 78 78 GLN GLN A . n A 1 79 VAL 79 79 79 VAL VAL A . n A 1 80 TRP 80 80 80 TRP TRP A . n A 1 81 LYS 81 81 81 LYS LYS A . n A 1 82 GLY 82 82 82 GLY GLY A . n A 1 83 ASP 83 83 83 ASP ASP A . n A 1 84 ALA 84 84 84 ALA ALA A . n A 1 85 GLU 85 85 85 GLU GLU A . n A 1 86 SER 86 86 86 SER SER A . n A 1 87 LYS 87 87 87 LYS LYS A . n A 1 88 ARG 88 88 88 ARG ARG A . n A 1 89 ALA 89 89 89 ALA ALA A . n A 1 90 THR 90 90 90 THR THR A . n A 1 91 ILE 91 91 91 ILE ILE A . n A 1 92 LYS 92 92 92 LYS LYS A . n A 1 93 VAL 93 93 93 VAL VAL A . n A 1 94 LEU 94 94 94 LEU LEU A . n A 1 95 VAL 95 95 95 VAL VAL A . n A 1 96 SER 96 96 96 SER SER A . n A 1 97 GLY 97 97 97 GLY GLY A . n A 1 98 GLN 98 98 98 GLN GLN A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 ASN 100 100 100 ASN ASN A . n A 1 101 MET 101 101 101 MET MET A . n A 1 102 ARG 102 102 102 ARG ARG A . n A 1 103 VAL 103 103 103 VAL VAL A . n A 1 104 LYS 104 104 104 LYS LYS A . n A 1 105 LEU 105 105 105 LEU LEU A . n A 1 106 CYS 106 106 106 CYS CYS A . n A 1 107 ASN 107 107 107 ASN ASN A . n A 1 108 GLU 108 108 108 GLU GLU A . n A 1 109 ASP 109 109 109 ASP ASP A . n A 1 110 GLY 110 110 110 GLY GLY A . n A 1 111 CYS 111 111 111 CYS CYS A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 VAL 113 113 113 VAL VAL A . n A 1 114 SER 114 114 114 SER SER A . n A 1 115 ASP 115 115 115 ASP ASP A . n A 1 116 PRO 116 116 116 PRO PRO A . n A 1 117 VAL 117 117 117 VAL VAL A . n A 1 118 LEU 118 118 118 LEU LEU A . n A 1 119 VAL 119 119 119 VAL VAL A . n A 1 120 LYS 120 120 120 LYS LYS A . n A 1 121 VAL 121 121 121 VAL VAL A . n A 1 122 ALA 122 122 122 ALA ALA A . n A 1 123 ASP 123 123 123 ASP ASP A . n A 1 124 THR 124 124 124 THR THR A . n A 1 125 ASP 125 125 125 ASP ASP A . n A 1 126 GLY 126 126 126 GLY GLY A . n A 1 127 GLY 127 127 127 GLY GLY A . n A 1 128 HIS 128 128 128 HIS HIS A . n A 1 129 LEU 129 129 129 LEU LEU A . n A 1 130 ALA 130 130 130 ALA ALA A . n A 1 131 PRO 131 131 131 PRO PRO A . n A 1 132 LEU 132 132 132 LEU LEU A . n A 1 133 GLU 133 133 133 GLU GLU A . n A 1 134 TYR 134 134 134 TYR TYR A . n A 1 135 THR 135 135 135 THR THR A . n A 1 136 TRP 136 136 136 TRP TRP A . n A 1 137 LEU 137 137 137 LEU LEU A . n A 1 138 GLU 138 138 138 GLU GLU A . n A 1 139 ASN 139 139 139 ASN ASN A . n A 1 140 ASN 140 140 140 ASN ASN A . n A 1 141 LYS 141 141 141 LYS LYS A . n A 1 142 PRO 142 142 142 PRO PRO A . n A 1 143 GLY 143 143 143 GLY GLY A . n A 1 144 ARG 144 144 144 ARG ARG A . n A 1 145 ARG 145 145 145 ARG ARG A . n A 1 146 GLU 146 146 146 GLU GLU A . n A 1 147 ASP 147 147 147 ASP ASP A . n A 1 148 LYS 148 148 148 LYS LYS A . n A 1 149 ILE 149 149 149 ILE ILE A . n A 1 150 VAL 150 150 150 VAL VAL A . n A 1 151 ALA 151 151 151 ALA ALA A . n A 1 152 ALA 152 152 152 ALA ALA A . n A 1 153 TYR 153 153 153 TYR TYR A . n A 1 154 PHE 154 154 154 PHE PHE A . n A 1 155 VAL 155 155 155 VAL VAL A . n A 1 156 GLU 156 156 156 GLU GLU A . n A 1 157 TRP 157 157 157 TRP TRP A . n A 1 158 GLY 158 158 158 GLY GLY A . n A 1 159 VAL 159 159 159 VAL VAL A . n A 1 160 TYR 160 160 160 TYR TYR A . n A 1 161 GLY 161 161 161 GLY GLY A . n A 1 162 ARG 162 162 162 ARG ARG A . n A 1 163 ASN 163 163 163 ASN ASN A . n A 1 164 PHE 164 164 164 PHE PHE A . n A 1 165 PRO 165 165 165 PRO PRO A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 ASP 167 167 167 ASP ASP A . n A 1 168 LYS 168 168 168 LYS LYS A . n A 1 169 VAL 169 169 169 VAL VAL A . n A 1 170 PRO 170 170 170 PRO PRO A . n A 1 171 LEU 171 171 171 LEU LEU A . n A 1 172 PRO 172 172 172 PRO PRO A . n A 1 173 ASN 173 173 173 ASN ASN A . n A 1 174 LEU 174 174 174 LEU LEU A . n A 1 175 SER 175 175 175 SER SER A . n A 1 176 HIS 176 176 176 HIS HIS A . n A 1 177 LEU 177 177 177 LEU LEU A . n A 1 178 LEU 178 178 178 LEU LEU A . n A 1 179 TYR 179 179 179 TYR TYR A . n A 1 180 GLY 180 180 180 GLY GLY A . n A 1 181 PHE 181 181 181 PHE PHE A . n A 1 182 ILE 182 182 182 ILE ILE A . n A 1 183 PRO 183 183 183 PRO PRO A . n A 1 184 ILE 184 184 184 ILE ILE A . n A 1 185 CYS 185 185 185 CYS CYS A . n A 1 186 GLY 186 186 186 GLY GLY A . n A 1 187 GLY 187 187 187 GLY GLY A . n A 1 188 ASP 188 188 188 ASP ASP A . n A 1 189 GLY 189 189 189 GLY GLY A . n A 1 190 ILE 190 190 190 ILE ILE A . n A 1 191 ASN 191 191 191 ASN ASN A . n A 1 192 ASP 192 192 192 ASP ASP A . n A 1 193 ALA 193 193 193 ALA ALA A . n A 1 194 LEU 194 194 194 LEU LEU A . n A 1 195 LYS 195 195 195 LYS LYS A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 ILE 197 197 197 ILE ILE A . n A 1 198 SER 198 198 198 SER SER A . n A 1 199 GLY 199 199 199 GLY GLY A . n A 1 200 SER 200 200 200 SER SER A . n A 1 201 PHE 201 201 201 PHE PHE A . n A 1 202 GLU 202 202 202 GLU GLU A . n A 1 203 SER 203 203 203 SER SER A . n A 1 204 LEU 204 204 204 LEU LEU A . n A 1 205 GLN 205 205 205 GLN GLN A . n A 1 206 ARG 206 206 206 ARG ARG A . n A 1 207 SER 207 207 207 SER SER A . n A 1 208 CYS 208 208 208 CYS CYS A . n A 1 209 LYS 209 209 209 LYS LYS A . n A 1 210 GLY 210 210 210 GLY GLY A . n A 1 211 ARG 211 211 211 ARG ARG A . n A 1 212 GLU 212 212 212 GLU GLU A . n A 1 213 ASP 213 213 213 ASP ASP A . n A 1 214 PHE 214 214 214 PHE PHE A . n A 1 215 LYS 215 215 215 LYS LYS A . n A 1 216 VAL 216 216 216 VAL VAL A . n A 1 217 ALA 217 217 217 ALA ALA A . n A 1 218 ILE 218 218 218 ILE ILE A . n A 1 219 HIS 219 219 219 HIS HIS A . n A 1 220 ASP 220 220 220 ASP ASP A . n A 1 221 PRO 221 221 221 PRO PRO A . n A 1 222 TRP 222 222 222 TRP TRP A . n A 1 223 ALA 223 223 223 ALA ALA A . n A 1 224 ALA 224 224 224 ALA ALA A . n A 1 225 VAL 225 225 225 VAL VAL A . n A 1 226 GLN 226 226 226 GLN GLN A . n A 1 227 LYS 227 227 227 LYS LYS A . n A 1 228 PRO 228 228 228 PRO PRO A . n A 1 229 GLN 229 229 229 GLN GLN A . n A 1 230 LYS 230 230 230 LYS LYS A . n A 1 231 SER 231 231 231 SER SER A . n A 1 232 VAL 232 232 232 VAL VAL A . n A 1 233 SER 233 233 233 SER SER A . n A 1 234 ALA 234 234 234 ALA ALA A . n A 1 235 TRP 235 235 235 TRP TRP A . n A 1 236 ASN 236 236 236 ASN ASN A . n A 1 237 GLU 237 237 237 GLU GLU A . n A 1 238 PRO 238 238 238 PRO PRO A . n A 1 239 TYR 239 239 239 TYR TYR A . n A 1 240 LYS 240 240 240 LYS LYS A . n A 1 241 GLY 241 241 241 GLY GLY A . n A 1 242 ASN 242 242 242 ASN ASN A . n A 1 243 PHE 243 243 243 PHE PHE A . n A 1 244 GLY 244 244 244 GLY GLY A . n A 1 245 GLN 245 245 245 GLN GLN A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 MET 247 247 247 MET MET A . n A 1 248 ALA 248 248 248 ALA ALA A . n A 1 249 ALA 249 249 249 ALA ALA A . n A 1 250 LYS 250 250 250 LYS LYS A . n A 1 251 LEU 251 251 251 LEU LEU A . n A 1 252 ALA 252 252 252 ALA ALA A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 PRO 254 254 254 PRO PRO A . n A 1 255 HIS 255 255 255 HIS HIS A . n A 1 256 LEU 256 256 256 LEU LEU A . n A 1 257 LYS 257 257 257 LYS LYS A . n A 1 258 ILE 258 258 258 ILE ILE A . n A 1 259 LEU 259 259 259 LEU LEU A . n A 1 260 PRO 260 260 260 PRO PRO A . n A 1 261 SER 261 261 261 SER SER A . n A 1 262 ILE 262 262 262 ILE ILE A . n A 1 263 GLY 263 263 263 GLY GLY A . n A 1 264 GLY 264 264 264 GLY GLY A . n A 1 265 TRP 265 265 265 TRP TRP A . n A 1 266 THR 266 266 266 THR THR A . n A 1 267 LEU 267 267 267 LEU LEU A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 ASP 269 269 269 ASP ASP A . n A 1 270 PRO 270 270 270 PRO PRO A . n A 1 271 PHE 271 271 271 PHE PHE A . n A 1 272 TYR 272 272 272 TYR TYR A . n A 1 273 PHE 273 273 273 PHE PHE A . n A 1 274 MET 274 274 274 MET MET A . n A 1 275 HIS 275 275 275 HIS HIS A . n A 1 276 ASP 276 276 276 ASP ASP A . n A 1 277 VAL 277 277 277 VAL VAL A . n A 1 278 GLU 278 278 278 GLU GLU A . n A 1 279 LYS 279 279 279 LYS LYS A . n A 1 280 ARG 280 280 280 ARG ARG A . n A 1 281 ASN 281 281 281 ASN ASN A . n A 1 282 VAL 282 282 282 VAL VAL A . n A 1 283 PHE 283 283 283 PHE PHE A . n A 1 284 VAL 284 284 284 VAL VAL A . n A 1 285 ASP 285 285 285 ASP ASP A . n A 1 286 SER 286 286 286 SER SER A . n A 1 287 VAL 287 287 287 VAL VAL A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 GLU 289 289 289 GLU GLU A . n A 1 290 PHE 290 290 290 PHE PHE A . n A 1 291 LEU 291 291 291 LEU LEU A . n A 1 292 GLN 292 292 292 GLN GLN A . n A 1 293 VAL 293 293 293 VAL VAL A . n A 1 294 TRP 294 294 294 TRP TRP A . n A 1 295 LYS 295 295 295 LYS LYS A . n A 1 296 PHE 296 296 296 PHE PHE A . n A 1 297 PHE 297 297 297 PHE PHE A . n A 1 298 ASP 298 298 298 ASP ASP A . n A 1 299 GLY 299 299 299 GLY GLY A . n A 1 300 VAL 300 300 300 VAL VAL A . n A 1 301 ASP 301 301 301 ASP ASP A . n A 1 302 VAL 302 302 302 VAL VAL A . n A 1 303 ASP 303 303 303 ASP ASP A . n A 1 304 TRP 304 304 304 TRP TRP A . n A 1 305 GLU 305 305 305 GLU GLU A . n A 1 306 PHE 306 306 306 PHE PHE A . n A 1 307 PRO 307 307 307 PRO PRO A . n A 1 308 GLY 308 308 308 GLY GLY A . n A 1 309 GLY 309 309 309 GLY GLY A . n A 1 310 LYS 310 310 310 LYS LYS A . n A 1 311 GLY 311 311 311 GLY GLY A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 ASN 313 313 313 ASN ASN A . n A 1 314 PRO 314 314 314 PRO PRO A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 LEU 316 316 316 LEU LEU A . n A 1 317 GLY 317 317 317 GLY GLY A . n A 1 318 ASP 318 318 318 ASP ASP A . n A 1 319 ALA 319 319 319 ALA ALA A . n A 1 320 GLU 320 320 320 GLU GLU A . n A 1 321 ARG 321 321 321 ARG ARG A . n A 1 322 ASP 322 322 322 ASP ASP A . n A 1 323 ALA 323 323 323 ALA ALA A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 THR 325 325 325 THR THR A . n A 1 326 TYR 326 326 326 TYR TYR A . n A 1 327 ILE 327 327 327 ILE ILE A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 LEU 329 329 329 LEU LEU A . n A 1 330 LEU 330 330 330 LEU LEU A . n A 1 331 GLU 331 331 331 GLU GLU A . n A 1 332 GLU 332 332 332 GLU GLU A . n A 1 333 LEU 333 333 333 LEU LEU A . n A 1 334 ARG 334 334 334 ARG ARG A . n A 1 335 ALA 335 335 335 ALA ALA A . n A 1 336 MET 336 336 336 MET MET A . n A 1 337 LEU 337 337 337 LEU LEU A . n A 1 338 ASP 338 338 338 ASP ASP A . n A 1 339 ASP 339 339 339 ASP ASP A . n A 1 340 LEU 340 340 340 LEU LEU A . n A 1 341 GLU 341 341 341 GLU GLU A . n A 1 342 ALA 342 342 342 ALA ALA A . n A 1 343 GLN 343 343 343 GLN GLN A . n A 1 344 THR 344 344 344 THR THR A . n A 1 345 GLY 345 345 345 GLY GLY A . n A 1 346 ARG 346 346 346 ARG ARG A . n A 1 347 VAL 347 347 347 VAL VAL A . n A 1 348 TYR 348 348 348 TYR TYR A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 LEU 350 350 350 LEU LEU A . n A 1 351 THR 351 351 351 THR THR A . n A 1 352 SER 352 352 352 SER SER A . n A 1 353 ALA 353 353 353 ALA ALA A . n A 1 354 ILE 354 354 354 ILE ILE A . n A 1 355 SER 355 355 355 SER SER A . n A 1 356 ALA 356 356 356 ALA ALA A . n A 1 357 GLY 357 357 357 GLY GLY A . n A 1 358 TYR 358 358 358 TYR TYR A . n A 1 359 ASP 359 359 359 ASP ASP A . n A 1 360 LYS 360 360 360 LYS LYS A . n A 1 361 ILE 361 361 361 ILE ILE A . n A 1 362 ALA 362 362 362 ALA ALA A . n A 1 363 VAL 363 363 363 VAL VAL A . n A 1 364 VAL 364 364 364 VAL VAL A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 TYR 366 366 366 TYR TYR A . n A 1 367 ALA 367 367 367 ALA ALA A . n A 1 368 GLU 368 368 368 GLU GLU A . n A 1 369 ALA 369 369 369 ALA ALA A . n A 1 370 GLN 370 370 370 GLN GLN A . n A 1 371 LYS 371 371 371 LYS LYS A . n A 1 372 SER 372 372 372 SER SER A . n A 1 373 LEU 373 373 373 LEU LEU A . n A 1 374 GLY 374 374 374 GLY GLY A . n A 1 375 LYS 375 375 375 LYS LYS A . n A 1 376 ILE 376 376 376 ILE ILE A . n A 1 377 PHE 377 377 377 PHE PHE A . n A 1 378 LEU 378 378 378 LEU LEU A . n A 1 379 MET 379 379 379 MET MET A . n A 1 380 SER 380 380 380 SER SER A . n A 1 381 TYR 381 381 381 TYR TYR A . n A 1 382 ASP 382 382 382 ASP ASP A . n A 1 383 PHE 383 383 383 PHE PHE A . n A 1 384 LYS 384 384 384 LYS LYS A . n A 1 385 GLY 385 385 385 GLY GLY A . n A 1 386 ALA 386 386 386 ALA ALA A . n A 1 387 TRP 387 387 387 TRP TRP A . n A 1 388 SER 388 388 388 SER SER A . n A 1 389 ASN 389 389 389 ASN ASN A . n A 1 390 THR 390 390 390 THR THR A . n A 1 391 ASP 391 391 391 ASP ASP A . n A 1 392 LEU 392 392 392 LEU LEU A . n A 1 393 GLY 393 393 393 GLY GLY A . n A 1 394 TYR 394 394 394 TYR TYR A . n A 1 395 GLN 395 395 395 GLN GLN A . n A 1 396 THR 396 396 396 THR THR A . n A 1 397 THR 397 397 397 THR THR A . n A 1 398 VAL 398 398 398 VAL VAL A . n A 1 399 TYR 399 399 399 TYR TYR A . n A 1 400 ALA 400 400 400 ALA ALA A . n A 1 401 PRO 401 401 401 PRO PRO A . n A 1 402 SER 402 402 402 SER SER A . n A 1 403 TRP 403 403 403 TRP TRP A . n A 1 404 ASN 404 404 404 ASN ASN A . n A 1 405 SER 405 405 405 SER SER A . n A 1 406 GLU 406 406 406 GLU GLU A . n A 1 407 GLU 407 407 407 GLU GLU A . n A 1 408 LEU 408 408 408 LEU LEU A . n A 1 409 TYR 409 409 409 TYR TYR A . n A 1 410 THR 410 410 410 THR THR A . n A 1 411 THR 411 411 411 THR THR A . n A 1 412 HIS 412 412 412 HIS HIS A . n A 1 413 TYR 413 413 413 TYR TYR A . n A 1 414 ALA 414 414 414 ALA ALA A . n A 1 415 VAL 415 415 415 VAL VAL A . n A 1 416 ASP 416 416 416 ASP ASP A . n A 1 417 ALA 417 417 417 ALA ALA A . n A 1 418 LEU 418 418 418 LEU LEU A . n A 1 419 LEU 419 419 419 LEU LEU A . n A 1 420 LYS 420 420 420 LYS LYS A . n A 1 421 GLN 421 421 421 GLN GLN A . n A 1 422 GLY 422 422 422 GLY GLY A . n A 1 423 VAL 423 423 423 VAL VAL A . n A 1 424 ASP 424 424 424 ASP ASP A . n A 1 425 PRO 425 425 425 PRO PRO A . n A 1 426 ASN 426 426 426 ASN ASN A . n A 1 427 LYS 427 427 427 LYS LYS A . n A 1 428 ILE 428 428 428 ILE ILE A . n A 1 429 ILE 429 429 429 ILE ILE A . n A 1 430 VAL 430 430 430 VAL VAL A . n A 1 431 GLY 431 431 431 GLY GLY A . n A 1 432 VAL 432 432 432 VAL VAL A . n A 1 433 ALA 433 433 433 ALA ALA A . n A 1 434 MET 434 434 434 MET MET A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 GLY 436 436 436 GLY GLY A . n A 1 437 ARG 437 437 437 ARG ARG A . n A 1 438 GLY 438 438 438 GLY GLY A . n A 1 439 TRP 439 439 439 TRP TRP A . n A 1 440 THR 440 440 440 THR THR A . n A 1 441 GLY 441 441 441 GLY GLY A . n A 1 442 VAL 442 442 442 VAL VAL A . n A 1 443 THR 443 443 443 THR THR A . n A 1 444 ASN 444 444 444 ASN ASN A . n A 1 445 TYR 445 445 445 TYR TYR A . n A 1 446 THR 446 446 446 THR THR A . n A 1 447 ASN 447 447 447 ASN ASN A . n A 1 448 ASP 448 448 448 ASP ASP A . n A 1 449 ASN 449 449 449 ASN ASN A . n A 1 450 TYR 450 450 450 TYR TYR A . n A 1 451 PHE 451 451 451 PHE PHE A . n A 1 452 SER 452 452 452 SER SER A . n A 1 453 GLY 453 453 453 GLY GLY A . n A 1 454 THR 454 454 454 THR THR A . n A 1 455 GLY 455 455 455 GLY GLY A . n A 1 456 ASN 456 456 456 ASN ASN A . n A 1 457 GLY 457 457 457 GLY GLY A . n A 1 458 PRO 458 458 458 PRO PRO A . n A 1 459 VAL 459 459 459 VAL VAL A . n A 1 460 SER 460 460 460 SER SER A . n A 1 461 GLY 461 461 461 GLY GLY A . n A 1 462 THR 462 462 462 THR THR A . n A 1 463 TRP 463 463 463 TRP TRP A . n A 1 464 GLU 464 464 464 GLU GLU A . n A 1 465 ASP 465 465 465 ASP ASP A . n A 1 466 GLY 466 466 466 GLY GLY A . n A 1 467 VAL 467 467 467 VAL VAL A . n A 1 468 VAL 468 468 468 VAL VAL A . n A 1 469 ASP 469 469 469 ASP ASP A . n A 1 470 TYR 470 470 470 TYR TYR A . n A 1 471 ARG 471 471 471 ARG ARG A . n A 1 472 GLN 472 472 472 GLN GLN A . n A 1 473 ILE 473 473 473 ILE ILE A . n A 1 474 GLN 474 474 474 GLN GLN A . n A 1 475 LYS 475 475 475 LYS LYS A . n A 1 476 ASP 476 476 476 ASP ASP A . n A 1 477 LEU 477 477 477 LEU LEU A . n A 1 478 ASN 478 478 478 ASN ASN A . n A 1 479 ASN 479 479 479 ASN ASN A . n A 1 480 TYR 480 480 480 TYR TYR A . n A 1 481 VAL 481 481 481 VAL VAL A . n A 1 482 TYR 482 482 482 TYR TYR A . n A 1 483 THR 483 483 483 THR THR A . n A 1 484 PHE 484 484 484 PHE PHE A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 SER 486 486 486 SER SER A . n A 1 487 ALA 487 487 487 ALA ALA A . n A 1 488 ALA 488 488 488 ALA ALA A . n A 1 489 GLN 489 489 489 GLN GLN A . n A 1 490 ALA 490 490 490 ALA ALA A . n A 1 491 SER 491 491 491 SER SER A . n A 1 492 TYR 492 492 492 TYR TYR A . n A 1 493 VAL 493 493 493 VAL VAL A . n A 1 494 PHE 494 494 494 PHE PHE A . n A 1 495 ASP 495 495 495 ASP ASP A . n A 1 496 LYS 496 496 496 LYS LYS A . n A 1 497 SER 497 497 497 SER SER A . n A 1 498 LYS 498 498 498 LYS LYS A . n A 1 499 GLY 499 499 499 GLY GLY A . n A 1 500 ASP 500 500 500 ASP ASP A . n A 1 501 LEU 501 501 501 LEU LEU A . n A 1 502 ILE 502 502 502 ILE ILE A . n A 1 503 SER 503 503 503 SER SER A . n A 1 504 PHE 504 504 504 PHE PHE A . n A 1 505 ASP 505 505 505 ASP ASP A . n A 1 506 SER 506 506 506 SER SER A . n A 1 507 VAL 507 507 507 VAL VAL A . n A 1 508 ASP 508 508 508 ASP ASP A . n A 1 509 SER 509 509 509 SER SER A . n A 1 510 VAL 510 510 510 VAL VAL A . n A 1 511 LEU 511 511 511 LEU LEU A . n A 1 512 GLY 512 512 512 GLY GLY A . n A 1 513 LYS 513 513 513 LYS LYS A . n A 1 514 VAL 514 514 514 VAL VAL A . n A 1 515 LYS 515 515 515 LYS LYS A . n A 1 516 TYR 516 516 516 TYR TYR A . n A 1 517 VAL 517 517 517 VAL VAL A . n A 1 518 ASP 518 518 518 ASP ASP A . n A 1 519 ARG 519 519 519 ARG ARG A . n A 1 520 ASN 520 520 520 ASN ASN A . n A 1 521 LYS 521 521 521 LYS LYS A . n A 1 522 LEU 522 522 522 LEU LEU A . n A 1 523 GLY 523 523 523 GLY GLY A . n A 1 524 GLY 524 524 524 GLY GLY A . n A 1 525 LEU 525 525 525 LEU LEU A . n A 1 526 PHE 526 526 526 PHE PHE A . n A 1 527 ALA 527 527 527 ALA ALA A . n A 1 528 TRP 528 528 528 TRP TRP A . n A 1 529 GLU 529 529 529 GLU GLU A . n A 1 530 ILE 530 530 530 ILE ILE A . n A 1 531 ASP 531 531 531 ASP ASP A . n A 1 532 ALA 532 532 532 ALA ALA A . n A 1 533 ASP 533 533 533 ASP ASP A . n A 1 534 ASN 534 534 534 ASN ASN A . n A 1 535 GLY 535 535 535 GLY GLY A . n A 1 536 ASP 536 536 536 ASP ASP A . n A 1 537 LEU 537 537 537 LEU LEU A . n A 1 538 LEU 538 538 538 LEU LEU A . n A 1 539 ASN 539 539 539 ASN ASN A . n A 1 540 ALA 540 540 540 ALA ALA A . n A 1 541 ILE 541 541 541 ILE ILE A . n A 1 542 ASN 542 542 542 ASN ASN A . n A 1 543 ALA 543 543 543 ALA ALA A . n A 1 544 GLN 544 544 544 GLN GLN A . n A 1 545 PHE 545 545 545 PHE PHE A . n B 1 1 MET 1 1 ? ? ? B . n B 1 2 LEU 2 2 ? ? ? B . n B 1 3 TYR 3 3 ? ? ? B . n B 1 4 LYS 4 4 ? ? ? B . n B 1 5 LEU 5 5 ? ? ? B . n B 1 6 LEU 6 6 ? ? ? B . n B 1 7 ASN 7 7 ? ? ? B . n B 1 8 VAL 8 8 ? ? ? B . n B 1 9 LEU 9 9 ? ? ? B . n B 1 10 TRP 10 10 ? ? ? B . n B 1 11 LEU 11 11 ? ? ? B . n B 1 12 VAL 12 12 ? ? ? B . n B 1 13 ALA 13 13 ? ? ? B . n B 1 14 VAL 14 14 ? ? ? B . n B 1 15 SER 15 15 ? ? ? B . n B 1 16 ASN 16 16 ? ? ? B . n B 1 17 ALA 17 17 ? ? ? B . n B 1 18 ILE 18 18 18 ILE ILE B . n B 1 19 PRO 19 19 19 PRO PRO B . n B 1 20 GLY 20 20 20 GLY GLY B . n B 1 21 THR 21 21 21 THR THR B . n B 1 22 PRO 22 22 22 PRO PRO B . n B 1 23 VAL 23 23 23 VAL VAL B . n B 1 24 ILE 24 24 24 ILE ILE B . n B 1 25 ASP 25 25 25 ASP ASP B . n B 1 26 TRP 26 26 26 TRP TRP B . n B 1 27 ALA 27 27 27 ALA ALA B . n B 1 28 ASP 28 28 28 ASP ASP B . n B 1 29 ARG 29 29 29 ARG ARG B . n B 1 30 ASN 30 30 30 ASN ASN B . n B 1 31 TYR 31 31 31 TYR TYR B . n B 1 32 ALA 32 32 32 ALA ALA B . n B 1 33 LEU 33 33 33 LEU LEU B . n B 1 34 VAL 34 34 34 VAL VAL B . n B 1 35 GLU 35 35 35 GLU GLU B . n B 1 36 ILE 36 36 36 ILE ILE B . n B 1 37 ASN 37 37 37 ASN ASN B . n B 1 38 TYR 38 38 38 TYR TYR B . n B 1 39 GLU 39 39 39 GLU GLU B . n B 1 40 ALA 40 40 40 ALA ALA B . n B 1 41 THR 41 41 41 THR THR B . n B 1 42 ALA 42 42 42 ALA ALA B . n B 1 43 TYR 43 43 43 TYR TYR B . n B 1 44 GLU 44 44 44 GLU GLU B . n B 1 45 ASN 45 45 45 ASN ASN B . n B 1 46 LEU 46 46 46 LEU LEU B . n B 1 47 ILE 47 47 47 ILE ILE B . n B 1 48 LYS 48 48 48 LYS LYS B . n B 1 49 PRO 49 49 49 PRO PRO B . n B 1 50 LYS 50 50 50 LYS LYS B . n B 1 51 GLU 51 51 51 GLU GLU B . n B 1 52 GLN 52 52 52 GLN GLN B . n B 1 53 VAL 53 53 53 VAL VAL B . n B 1 54 ASP 54 54 54 ASP ASP B . n B 1 55 VAL 55 55 55 VAL VAL B . n B 1 56 GLN 56 56 56 GLN GLN B . n B 1 57 VAL 57 57 57 VAL VAL B . n B 1 58 SER 58 58 58 SER SER B . n B 1 59 TRP 59 59 59 TRP TRP B . n B 1 60 ASN 60 60 60 ASN ASN B . n B 1 61 VAL 61 61 61 VAL VAL B . n B 1 62 TRP 62 62 62 TRP TRP B . n B 1 63 ASN 63 63 63 ASN ASN B . n B 1 64 GLY 64 64 64 GLY GLY B . n B 1 65 ASP 65 65 65 ASP ASP B . n B 1 66 ILE 66 66 66 ILE ILE B . n B 1 67 GLY 67 67 67 GLY GLY B . n B 1 68 ASP 68 68 68 ASP ASP B . n B 1 69 ILE 69 69 69 ILE ILE B . n B 1 70 ALA 70 70 70 ALA ALA B . n B 1 71 TYR 71 71 71 TYR TYR B . n B 1 72 VAL 72 72 72 VAL VAL B . n B 1 73 LEU 73 73 73 LEU LEU B . n B 1 74 PHE 74 74 74 PHE PHE B . n B 1 75 ASP 75 75 75 ASP ASP B . n B 1 76 GLU 76 76 76 GLU GLU B . n B 1 77 GLN 77 77 77 GLN GLN B . n B 1 78 GLN 78 78 78 GLN GLN B . n B 1 79 VAL 79 79 79 VAL VAL B . n B 1 80 TRP 80 80 80 TRP TRP B . n B 1 81 LYS 81 81 81 LYS LYS B . n B 1 82 GLY 82 82 82 GLY GLY B . n B 1 83 ASP 83 83 83 ASP ASP B . n B 1 84 ALA 84 84 84 ALA ALA B . n B 1 85 GLU 85 85 85 GLU GLU B . n B 1 86 SER 86 86 86 SER SER B . n B 1 87 LYS 87 87 87 LYS LYS B . n B 1 88 ARG 88 88 88 ARG ARG B . n B 1 89 ALA 89 89 89 ALA ALA B . n B 1 90 THR 90 90 90 THR THR B . n B 1 91 ILE 91 91 91 ILE ILE B . n B 1 92 LYS 92 92 92 LYS LYS B . n B 1 93 VAL 93 93 93 VAL VAL B . n B 1 94 LEU 94 94 94 LEU LEU B . n B 1 95 VAL 95 95 95 VAL VAL B . n B 1 96 SER 96 96 96 SER SER B . n B 1 97 GLY 97 97 97 GLY GLY B . n B 1 98 GLN 98 98 98 GLN GLN B . n B 1 99 PHE 99 99 99 PHE PHE B . n B 1 100 ASN 100 100 100 ASN ASN B . n B 1 101 MET 101 101 101 MET MET B . n B 1 102 ARG 102 102 102 ARG ARG B . n B 1 103 VAL 103 103 103 VAL VAL B . n B 1 104 LYS 104 104 104 LYS LYS B . n B 1 105 LEU 105 105 105 LEU LEU B . n B 1 106 CYS 106 106 106 CYS CYS B . n B 1 107 ASN 107 107 107 ASN ASN B . n B 1 108 GLU 108 108 108 GLU GLU B . n B 1 109 ASP 109 109 109 ASP ASP B . n B 1 110 GLY 110 110 110 GLY GLY B . n B 1 111 CYS 111 111 111 CYS CYS B . n B 1 112 SER 112 112 112 SER SER B . n B 1 113 VAL 113 113 113 VAL VAL B . n B 1 114 SER 114 114 114 SER SER B . n B 1 115 ASP 115 115 115 ASP ASP B . n B 1 116 PRO 116 116 116 PRO PRO B . n B 1 117 VAL 117 117 117 VAL VAL B . n B 1 118 LEU 118 118 118 LEU LEU B . n B 1 119 VAL 119 119 119 VAL VAL B . n B 1 120 LYS 120 120 120 LYS LYS B . n B 1 121 VAL 121 121 121 VAL VAL B . n B 1 122 ALA 122 122 122 ALA ALA B . n B 1 123 ASP 123 123 123 ASP ASP B . n B 1 124 THR 124 124 124 THR THR B . n B 1 125 ASP 125 125 125 ASP ASP B . n B 1 126 GLY 126 126 126 GLY GLY B . n B 1 127 GLY 127 127 127 GLY GLY B . n B 1 128 HIS 128 128 128 HIS HIS B . n B 1 129 LEU 129 129 129 LEU LEU B . n B 1 130 ALA 130 130 130 ALA ALA B . n B 1 131 PRO 131 131 131 PRO PRO B . n B 1 132 LEU 132 132 132 LEU LEU B . n B 1 133 GLU 133 133 133 GLU GLU B . n B 1 134 TYR 134 134 134 TYR TYR B . n B 1 135 THR 135 135 135 THR THR B . n B 1 136 TRP 136 136 136 TRP TRP B . n B 1 137 LEU 137 137 137 LEU LEU B . n B 1 138 GLU 138 138 138 GLU GLU B . n B 1 139 ASN 139 139 139 ASN ASN B . n B 1 140 ASN 140 140 140 ASN ASN B . n B 1 141 LYS 141 141 141 LYS LYS B . n B 1 142 PRO 142 142 142 PRO PRO B . n B 1 143 GLY 143 143 143 GLY GLY B . n B 1 144 ARG 144 144 144 ARG ARG B . n B 1 145 ARG 145 145 145 ARG ARG B . n B 1 146 GLU 146 146 146 GLU GLU B . n B 1 147 ASP 147 147 147 ASP ASP B . n B 1 148 LYS 148 148 148 LYS LYS B . n B 1 149 ILE 149 149 149 ILE ILE B . n B 1 150 VAL 150 150 150 VAL VAL B . n B 1 151 ALA 151 151 151 ALA ALA B . n B 1 152 ALA 152 152 152 ALA ALA B . n B 1 153 TYR 153 153 153 TYR TYR B . n B 1 154 PHE 154 154 154 PHE PHE B . n B 1 155 VAL 155 155 155 VAL VAL B . n B 1 156 GLU 156 156 156 GLU GLU B . n B 1 157 TRP 157 157 157 TRP TRP B . n B 1 158 GLY 158 158 158 GLY GLY B . n B 1 159 VAL 159 159 159 VAL VAL B . n B 1 160 TYR 160 160 160 TYR TYR B . n B 1 161 GLY 161 161 161 GLY GLY B . n B 1 162 ARG 162 162 162 ARG ARG B . n B 1 163 ASN 163 163 163 ASN ASN B . n B 1 164 PHE 164 164 164 PHE PHE B . n B 1 165 PRO 165 165 165 PRO PRO B . n B 1 166 VAL 166 166 166 VAL VAL B . n B 1 167 ASP 167 167 167 ASP ASP B . n B 1 168 LYS 168 168 168 LYS LYS B . n B 1 169 VAL 169 169 169 VAL VAL B . n B 1 170 PRO 170 170 170 PRO PRO B . n B 1 171 LEU 171 171 171 LEU LEU B . n B 1 172 PRO 172 172 172 PRO PRO B . n B 1 173 ASN 173 173 173 ASN ASN B . n B 1 174 LEU 174 174 174 LEU LEU B . n B 1 175 SER 175 175 175 SER SER B . n B 1 176 HIS 176 176 176 HIS HIS B . n B 1 177 LEU 177 177 177 LEU LEU B . n B 1 178 LEU 178 178 178 LEU LEU B . n B 1 179 TYR 179 179 179 TYR TYR B . n B 1 180 GLY 180 180 180 GLY GLY B . n B 1 181 PHE 181 181 181 PHE PHE B . n B 1 182 ILE 182 182 182 ILE ILE B . n B 1 183 PRO 183 183 183 PRO PRO B . n B 1 184 ILE 184 184 184 ILE ILE B . n B 1 185 CYS 185 185 185 CYS CYS B . n B 1 186 GLY 186 186 186 GLY GLY B . n B 1 187 GLY 187 187 187 GLY GLY B . n B 1 188 ASP 188 188 188 ASP ASP B . n B 1 189 GLY 189 189 189 GLY GLY B . n B 1 190 ILE 190 190 190 ILE ILE B . n B 1 191 ASN 191 191 191 ASN ASN B . n B 1 192 ASP 192 192 192 ASP ASP B . n B 1 193 ALA 193 193 193 ALA ALA B . n B 1 194 LEU 194 194 194 LEU LEU B . n B 1 195 LYS 195 195 195 LYS LYS B . n B 1 196 THR 196 196 196 THR THR B . n B 1 197 ILE 197 197 197 ILE ILE B . n B 1 198 SER 198 198 198 SER SER B . n B 1 199 GLY 199 199 199 GLY GLY B . n B 1 200 SER 200 200 200 SER SER B . n B 1 201 PHE 201 201 201 PHE PHE B . n B 1 202 GLU 202 202 202 GLU GLU B . n B 1 203 SER 203 203 203 SER SER B . n B 1 204 LEU 204 204 204 LEU LEU B . n B 1 205 GLN 205 205 205 GLN GLN B . n B 1 206 ARG 206 206 206 ARG ARG B . n B 1 207 SER 207 207 207 SER SER B . n B 1 208 CYS 208 208 208 CYS CYS B . n B 1 209 LYS 209 209 209 LYS LYS B . n B 1 210 GLY 210 210 210 GLY GLY B . n B 1 211 ARG 211 211 211 ARG ARG B . n B 1 212 GLU 212 212 212 GLU GLU B . n B 1 213 ASP 213 213 213 ASP ASP B . n B 1 214 PHE 214 214 214 PHE PHE B . n B 1 215 LYS 215 215 215 LYS LYS B . n B 1 216 VAL 216 216 216 VAL VAL B . n B 1 217 ALA 217 217 217 ALA ALA B . n B 1 218 ILE 218 218 218 ILE ILE B . n B 1 219 HIS 219 219 219 HIS HIS B . n B 1 220 ASP 220 220 220 ASP ASP B . n B 1 221 PRO 221 221 221 PRO PRO B . n B 1 222 TRP 222 222 222 TRP TRP B . n B 1 223 ALA 223 223 223 ALA ALA B . n B 1 224 ALA 224 224 224 ALA ALA B . n B 1 225 VAL 225 225 225 VAL VAL B . n B 1 226 GLN 226 226 226 GLN GLN B . n B 1 227 LYS 227 227 227 LYS LYS B . n B 1 228 PRO 228 228 228 PRO PRO B . n B 1 229 GLN 229 229 229 GLN GLN B . n B 1 230 LYS 230 230 230 LYS LYS B . n B 1 231 SER 231 231 231 SER SER B . n B 1 232 VAL 232 232 232 VAL VAL B . n B 1 233 SER 233 233 233 SER SER B . n B 1 234 ALA 234 234 234 ALA ALA B . n B 1 235 TRP 235 235 235 TRP TRP B . n B 1 236 ASN 236 236 236 ASN ASN B . n B 1 237 GLU 237 237 237 GLU GLU B . n B 1 238 PRO 238 238 238 PRO PRO B . n B 1 239 TYR 239 239 239 TYR TYR B . n B 1 240 LYS 240 240 240 LYS LYS B . n B 1 241 GLY 241 241 241 GLY GLY B . n B 1 242 ASN 242 242 242 ASN ASN B . n B 1 243 PHE 243 243 243 PHE PHE B . n B 1 244 GLY 244 244 244 GLY GLY B . n B 1 245 GLN 245 245 245 GLN GLN B . n B 1 246 LEU 246 246 246 LEU LEU B . n B 1 247 MET 247 247 247 MET MET B . n B 1 248 ALA 248 248 248 ALA ALA B . n B 1 249 ALA 249 249 249 ALA ALA B . n B 1 250 LYS 250 250 250 LYS LYS B . n B 1 251 LEU 251 251 251 LEU LEU B . n B 1 252 ALA 252 252 252 ALA ALA B . n B 1 253 ASN 253 253 253 ASN ASN B . n B 1 254 PRO 254 254 254 PRO PRO B . n B 1 255 HIS 255 255 255 HIS HIS B . n B 1 256 LEU 256 256 256 LEU LEU B . n B 1 257 LYS 257 257 257 LYS LYS B . n B 1 258 ILE 258 258 258 ILE ILE B . n B 1 259 LEU 259 259 259 LEU LEU B . n B 1 260 PRO 260 260 260 PRO PRO B . n B 1 261 SER 261 261 261 SER SER B . n B 1 262 ILE 262 262 262 ILE ILE B . n B 1 263 GLY 263 263 263 GLY GLY B . n B 1 264 GLY 264 264 264 GLY GLY B . n B 1 265 TRP 265 265 265 TRP TRP B . n B 1 266 THR 266 266 266 THR THR B . n B 1 267 LEU 267 267 267 LEU LEU B . n B 1 268 SER 268 268 268 SER SER B . n B 1 269 ASP 269 269 269 ASP ASP B . n B 1 270 PRO 270 270 270 PRO PRO B . n B 1 271 PHE 271 271 271 PHE PHE B . n B 1 272 TYR 272 272 272 TYR TYR B . n B 1 273 PHE 273 273 273 PHE PHE B . n B 1 274 MET 274 274 274 MET MET B . n B 1 275 HIS 275 275 275 HIS HIS B . n B 1 276 ASP 276 276 276 ASP ASP B . n B 1 277 VAL 277 277 277 VAL VAL B . n B 1 278 GLU 278 278 278 GLU GLU B . n B 1 279 LYS 279 279 279 LYS LYS B . n B 1 280 ARG 280 280 280 ARG ARG B . n B 1 281 ASN 281 281 281 ASN ASN B . n B 1 282 VAL 282 282 282 VAL VAL B . n B 1 283 PHE 283 283 283 PHE PHE B . n B 1 284 VAL 284 284 284 VAL VAL B . n B 1 285 ASP 285 285 285 ASP ASP B . n B 1 286 SER 286 286 286 SER SER B . n B 1 287 VAL 287 287 287 VAL VAL B . n B 1 288 LYS 288 288 288 LYS LYS B . n B 1 289 GLU 289 289 289 GLU GLU B . n B 1 290 PHE 290 290 290 PHE PHE B . n B 1 291 LEU 291 291 291 LEU LEU B . n B 1 292 GLN 292 292 292 GLN GLN B . n B 1 293 VAL 293 293 293 VAL VAL B . n B 1 294 TRP 294 294 294 TRP TRP B . n B 1 295 LYS 295 295 295 LYS LYS B . n B 1 296 PHE 296 296 296 PHE PHE B . n B 1 297 PHE 297 297 297 PHE PHE B . n B 1 298 ASP 298 298 298 ASP ASP B . n B 1 299 GLY 299 299 299 GLY GLY B . n B 1 300 VAL 300 300 300 VAL VAL B . n B 1 301 ASP 301 301 301 ASP ASP B . n B 1 302 VAL 302 302 302 VAL VAL B . n B 1 303 ASP 303 303 303 ASP ASP B . n B 1 304 TRP 304 304 304 TRP TRP B . n B 1 305 GLU 305 305 305 GLU GLU B . n B 1 306 PHE 306 306 306 PHE PHE B . n B 1 307 PRO 307 307 307 PRO PRO B . n B 1 308 GLY 308 308 308 GLY GLY B . n B 1 309 GLY 309 309 309 GLY GLY B . n B 1 310 LYS 310 310 310 LYS LYS B . n B 1 311 GLY 311 311 311 GLY GLY B . n B 1 312 ALA 312 312 312 ALA ALA B . n B 1 313 ASN 313 313 313 ASN ASN B . n B 1 314 PRO 314 314 314 PRO PRO B . n B 1 315 SER 315 315 315 SER SER B . n B 1 316 LEU 316 316 316 LEU LEU B . n B 1 317 GLY 317 317 317 GLY GLY B . n B 1 318 ASP 318 318 318 ASP ASP B . n B 1 319 ALA 319 319 319 ALA ALA B . n B 1 320 GLU 320 320 320 GLU GLU B . n B 1 321 ARG 321 321 321 ARG ARG B . n B 1 322 ASP 322 322 322 ASP ASP B . n B 1 323 ALA 323 323 323 ALA ALA B . n B 1 324 LYS 324 324 324 LYS LYS B . n B 1 325 THR 325 325 325 THR THR B . n B 1 326 TYR 326 326 326 TYR TYR B . n B 1 327 ILE 327 327 327 ILE ILE B . n B 1 328 LEU 328 328 328 LEU LEU B . n B 1 329 LEU 329 329 329 LEU LEU B . n B 1 330 LEU 330 330 330 LEU LEU B . n B 1 331 GLU 331 331 331 GLU GLU B . n B 1 332 GLU 332 332 332 GLU GLU B . n B 1 333 LEU 333 333 333 LEU LEU B . n B 1 334 ARG 334 334 334 ARG ARG B . n B 1 335 ALA 335 335 335 ALA ALA B . n B 1 336 MET 336 336 336 MET MET B . n B 1 337 LEU 337 337 337 LEU LEU B . n B 1 338 ASP 338 338 338 ASP ASP B . n B 1 339 ASP 339 339 339 ASP ASP B . n B 1 340 LEU 340 340 340 LEU LEU B . n B 1 341 GLU 341 341 341 GLU GLU B . n B 1 342 ALA 342 342 342 ALA ALA B . n B 1 343 GLN 343 343 343 GLN GLN B . n B 1 344 THR 344 344 344 THR THR B . n B 1 345 GLY 345 345 345 GLY GLY B . n B 1 346 ARG 346 346 346 ARG ARG B . n B 1 347 VAL 347 347 347 VAL VAL B . n B 1 348 TYR 348 348 348 TYR TYR B . n B 1 349 GLU 349 349 349 GLU GLU B . n B 1 350 LEU 350 350 350 LEU LEU B . n B 1 351 THR 351 351 351 THR THR B . n B 1 352 SER 352 352 352 SER SER B . n B 1 353 ALA 353 353 353 ALA ALA B . n B 1 354 ILE 354 354 354 ILE ILE B . n B 1 355 SER 355 355 355 SER SER B . n B 1 356 ALA 356 356 356 ALA ALA B . n B 1 357 GLY 357 357 357 GLY GLY B . n B 1 358 TYR 358 358 358 TYR TYR B . n B 1 359 ASP 359 359 359 ASP ASP B . n B 1 360 LYS 360 360 360 LYS LYS B . n B 1 361 ILE 361 361 361 ILE ILE B . n B 1 362 ALA 362 362 362 ALA ALA B . n B 1 363 VAL 363 363 363 VAL VAL B . n B 1 364 VAL 364 364 364 VAL VAL B . n B 1 365 ASN 365 365 365 ASN ASN B . n B 1 366 TYR 366 366 366 TYR TYR B . n B 1 367 ALA 367 367 367 ALA ALA B . n B 1 368 GLU 368 368 368 GLU GLU B . n B 1 369 ALA 369 369 369 ALA ALA B . n B 1 370 GLN 370 370 370 GLN GLN B . n B 1 371 LYS 371 371 371 LYS LYS B . n B 1 372 SER 372 372 372 SER SER B . n B 1 373 LEU 373 373 373 LEU LEU B . n B 1 374 GLY 374 374 374 GLY GLY B . n B 1 375 LYS 375 375 375 LYS LYS B . n B 1 376 ILE 376 376 376 ILE ILE B . n B 1 377 PHE 377 377 377 PHE PHE B . n B 1 378 LEU 378 378 378 LEU LEU B . n B 1 379 MET 379 379 379 MET MET B . n B 1 380 SER 380 380 380 SER SER B . n B 1 381 TYR 381 381 381 TYR TYR B . n B 1 382 ASP 382 382 382 ASP ASP B . n B 1 383 PHE 383 383 383 PHE PHE B . n B 1 384 LYS 384 384 384 LYS LYS B . n B 1 385 GLY 385 385 385 GLY GLY B . n B 1 386 ALA 386 386 386 ALA ALA B . n B 1 387 TRP 387 387 387 TRP TRP B . n B 1 388 SER 388 388 388 SER SER B . n B 1 389 ASN 389 389 389 ASN ASN B . n B 1 390 THR 390 390 390 THR THR B . n B 1 391 ASP 391 391 391 ASP ASP B . n B 1 392 LEU 392 392 392 LEU LEU B . n B 1 393 GLY 393 393 393 GLY GLY B . n B 1 394 TYR 394 394 394 TYR TYR B . n B 1 395 GLN 395 395 395 GLN GLN B . n B 1 396 THR 396 396 396 THR THR B . n B 1 397 THR 397 397 397 THR THR B . n B 1 398 VAL 398 398 398 VAL VAL B . n B 1 399 TYR 399 399 399 TYR TYR B . n B 1 400 ALA 400 400 400 ALA ALA B . n B 1 401 PRO 401 401 401 PRO PRO B . n B 1 402 SER 402 402 402 SER SER B . n B 1 403 TRP 403 403 403 TRP TRP B . n B 1 404 ASN 404 404 404 ASN ASN B . n B 1 405 SER 405 405 405 SER SER B . n B 1 406 GLU 406 406 406 GLU GLU B . n B 1 407 GLU 407 407 407 GLU GLU B . n B 1 408 LEU 408 408 408 LEU LEU B . n B 1 409 TYR 409 409 409 TYR TYR B . n B 1 410 THR 410 410 410 THR THR B . n B 1 411 THR 411 411 411 THR THR B . n B 1 412 HIS 412 412 412 HIS HIS B . n B 1 413 TYR 413 413 413 TYR TYR B . n B 1 414 ALA 414 414 414 ALA ALA B . n B 1 415 VAL 415 415 415 VAL VAL B . n B 1 416 ASP 416 416 416 ASP ASP B . n B 1 417 ALA 417 417 417 ALA ALA B . n B 1 418 LEU 418 418 418 LEU LEU B . n B 1 419 LEU 419 419 419 LEU LEU B . n B 1 420 LYS 420 420 420 LYS LYS B . n B 1 421 GLN 421 421 421 GLN GLN B . n B 1 422 GLY 422 422 422 GLY GLY B . n B 1 423 VAL 423 423 423 VAL VAL B . n B 1 424 ASP 424 424 424 ASP ASP B . n B 1 425 PRO 425 425 425 PRO PRO B . n B 1 426 ASN 426 426 426 ASN ASN B . n B 1 427 LYS 427 427 427 LYS LYS B . n B 1 428 ILE 428 428 428 ILE ILE B . n B 1 429 ILE 429 429 429 ILE ILE B . n B 1 430 VAL 430 430 430 VAL VAL B . n B 1 431 GLY 431 431 431 GLY GLY B . n B 1 432 VAL 432 432 432 VAL VAL B . n B 1 433 ALA 433 433 433 ALA ALA B . n B 1 434 MET 434 434 434 MET MET B . n B 1 435 TYR 435 435 435 TYR TYR B . n B 1 436 GLY 436 436 436 GLY GLY B . n B 1 437 ARG 437 437 437 ARG ARG B . n B 1 438 GLY 438 438 438 GLY GLY B . n B 1 439 TRP 439 439 439 TRP TRP B . n B 1 440 THR 440 440 440 THR THR B . n B 1 441 GLY 441 441 441 GLY GLY B . n B 1 442 VAL 442 442 442 VAL VAL B . n B 1 443 THR 443 443 443 THR THR B . n B 1 444 ASN 444 444 444 ASN ASN B . n B 1 445 TYR 445 445 445 TYR TYR B . n B 1 446 THR 446 446 446 THR THR B . n B 1 447 ASN 447 447 447 ASN ASN B . n B 1 448 ASP 448 448 448 ASP ASP B . n B 1 449 ASN 449 449 449 ASN ASN B . n B 1 450 TYR 450 450 450 TYR TYR B . n B 1 451 PHE 451 451 451 PHE PHE B . n B 1 452 SER 452 452 452 SER SER B . n B 1 453 GLY 453 453 453 GLY GLY B . n B 1 454 THR 454 454 454 THR THR B . n B 1 455 GLY 455 455 455 GLY GLY B . n B 1 456 ASN 456 456 456 ASN ASN B . n B 1 457 GLY 457 457 457 GLY GLY B . n B 1 458 PRO 458 458 458 PRO PRO B . n B 1 459 VAL 459 459 459 VAL VAL B . n B 1 460 SER 460 460 460 SER SER B . n B 1 461 GLY 461 461 461 GLY GLY B . n B 1 462 THR 462 462 462 THR THR B . n B 1 463 TRP 463 463 463 TRP TRP B . n B 1 464 GLU 464 464 464 GLU GLU B . n B 1 465 ASP 465 465 465 ASP ASP B . n B 1 466 GLY 466 466 466 GLY GLY B . n B 1 467 VAL 467 467 467 VAL VAL B . n B 1 468 VAL 468 468 468 VAL VAL B . n B 1 469 ASP 469 469 469 ASP ASP B . n B 1 470 TYR 470 470 470 TYR TYR B . n B 1 471 ARG 471 471 471 ARG ARG B . n B 1 472 GLN 472 472 472 GLN GLN B . n B 1 473 ILE 473 473 473 ILE ILE B . n B 1 474 GLN 474 474 474 GLN GLN B . n B 1 475 LYS 475 475 475 LYS LYS B . n B 1 476 ASP 476 476 476 ASP ASP B . n B 1 477 LEU 477 477 477 LEU LEU B . n B 1 478 ASN 478 478 478 ASN ASN B . n B 1 479 ASN 479 479 479 ASN ASN B . n B 1 480 TYR 480 480 480 TYR TYR B . n B 1 481 VAL 481 481 481 VAL VAL B . n B 1 482 TYR 482 482 482 TYR TYR B . n B 1 483 THR 483 483 483 THR THR B . n B 1 484 PHE 484 484 484 PHE PHE B . n B 1 485 ASP 485 485 485 ASP ASP B . n B 1 486 SER 486 486 486 SER SER B . n B 1 487 ALA 487 487 487 ALA ALA B . n B 1 488 ALA 488 488 488 ALA ALA B . n B 1 489 GLN 489 489 489 GLN GLN B . n B 1 490 ALA 490 490 490 ALA ALA B . n B 1 491 SER 491 491 491 SER SER B . n B 1 492 TYR 492 492 492 TYR TYR B . n B 1 493 VAL 493 493 493 VAL VAL B . n B 1 494 PHE 494 494 494 PHE PHE B . n B 1 495 ASP 495 495 495 ASP ASP B . n B 1 496 LYS 496 496 496 LYS LYS B . n B 1 497 SER 497 497 497 SER SER B . n B 1 498 LYS 498 498 498 LYS LYS B . n B 1 499 GLY 499 499 499 GLY GLY B . n B 1 500 ASP 500 500 500 ASP ASP B . n B 1 501 LEU 501 501 501 LEU LEU B . n B 1 502 ILE 502 502 502 ILE ILE B . n B 1 503 SER 503 503 503 SER SER B . n B 1 504 PHE 504 504 504 PHE PHE B . n B 1 505 ASP 505 505 505 ASP ASP B . n B 1 506 SER 506 506 506 SER SER B . n B 1 507 VAL 507 507 507 VAL VAL B . n B 1 508 ASP 508 508 508 ASP ASP B . n B 1 509 SER 509 509 509 SER SER B . n B 1 510 VAL 510 510 510 VAL VAL B . n B 1 511 LEU 511 511 511 LEU LEU B . n B 1 512 GLY 512 512 512 GLY GLY B . n B 1 513 LYS 513 513 513 LYS LYS B . n B 1 514 VAL 514 514 514 VAL VAL B . n B 1 515 LYS 515 515 515 LYS LYS B . n B 1 516 TYR 516 516 516 TYR TYR B . n B 1 517 VAL 517 517 517 VAL VAL B . n B 1 518 ASP 518 518 518 ASP ASP B . n B 1 519 ARG 519 519 519 ARG ARG B . n B 1 520 ASN 520 520 520 ASN ASN B . n B 1 521 LYS 521 521 521 LYS LYS B . n B 1 522 LEU 522 522 522 LEU LEU B . n B 1 523 GLY 523 523 523 GLY GLY B . n B 1 524 GLY 524 524 524 GLY GLY B . n B 1 525 LEU 525 525 525 LEU LEU B . n B 1 526 PHE 526 526 526 PHE PHE B . n B 1 527 ALA 527 527 527 ALA ALA B . n B 1 528 TRP 528 528 528 TRP TRP B . n B 1 529 GLU 529 529 529 GLU GLU B . n B 1 530 ILE 530 530 530 ILE ILE B . n B 1 531 ASP 531 531 531 ASP ASP B . n B 1 532 ALA 532 532 532 ALA ALA B . n B 1 533 ASP 533 533 533 ASP ASP B . n B 1 534 ASN 534 534 534 ASN ASN B . n B 1 535 GLY 535 535 535 GLY GLY B . n B 1 536 ASP 536 536 536 ASP ASP B . n B 1 537 LEU 537 537 537 LEU LEU B . n B 1 538 LEU 538 538 538 LEU LEU B . n B 1 539 ASN 539 539 539 ASN ASN B . n B 1 540 ALA 540 540 540 ALA ALA B . n B 1 541 ILE 541 541 541 ILE ILE B . n B 1 542 ASN 542 542 542 ASN ASN B . n B 1 543 ALA 543 543 543 ALA ALA B . n B 1 544 GLN 544 544 544 GLN GLN B . n B 1 545 PHE 545 545 545 PHE PHE B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 601 546 NAG NAG A . D 2 NAG 1 602 547 NAG NAG A . E 2 NAG 1 603 550 NAG NAG A . F 3 SN5 1 604 561 SN5 SN5 A . G 4 58Y 1 605 560 58Y NGT A . H 5 CL 1 606 554 CL CL A . I 6 SO4 1 607 766 SO4 SO4 A . J 6 SO4 1 608 767 SO4 SO4 A . K 6 SO4 1 609 768 SO4 SO4 A . L 2 NAG 1 601 550 NAG NAG B . M 2 NAG 1 602 552 NAG NAG B . N 2 NAG 1 603 553 NAG NAG B . O 3 SN5 1 604 561 SN5 SN5 B . P 4 58Y 1 605 560 58Y NGT B . Q 6 SO4 1 606 901 SO4 SO4 B . R 6 SO4 1 607 902 SO4 SO4 B . S 7 HOH 1 701 616 HOH HOH A . S 7 HOH 2 702 609 HOH HOH A . S 7 HOH 3 703 717 HOH HOH A . S 7 HOH 4 704 765 HOH HOH A . T 7 HOH 1 701 565 HOH HOH B . T 7 HOH 2 702 577 HOH HOH B . T 7 HOH 3 703 900 HOH HOH B . T 7 HOH 4 704 684 HOH HOH B . T 7 HOH 5 705 774 HOH HOH B . T 7 HOH 6 706 639 HOH HOH B . T 7 HOH 7 707 750 HOH HOH B . T 7 HOH 8 708 877 HOH HOH B . T 7 HOH 9 709 736 HOH HOH B . T 7 HOH 10 710 702 HOH HOH B . T 7 HOH 11 711 641 HOH HOH B . T 7 HOH 12 712 854 HOH HOH B . # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA monomeric 1 2 author_and_software_defined_assembly PISA monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,C,D,E,F,G,H,I,J,K,S 2 1 B,L,M,N,O,P,Q,R,T # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2016-09-07 2 'Structure model' 1 1 2017-09-20 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Author supporting evidence' 2 2 'Structure model' 'Derived calculations' # loop_ _pdbx_audit_revision_category.ordinal _pdbx_audit_revision_category.revision_ordinal _pdbx_audit_revision_category.data_content_type _pdbx_audit_revision_category.category 1 2 'Structure model' pdbx_audit_support 2 2 'Structure model' pdbx_struct_oper_list # loop_ _pdbx_audit_revision_item.ordinal _pdbx_audit_revision_item.revision_ordinal _pdbx_audit_revision_item.data_content_type _pdbx_audit_revision_item.item 1 2 'Structure model' '_pdbx_audit_support.funding_organization' 2 2 'Structure model' '_pdbx_struct_oper_list.symmetry_operation' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.10.1_2155: ???)' 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? . 3 ? phasing ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? . 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 NZ B LYS 215 ? ? O B VAL 282 ? ? 2.05 2 1 OH B TYR 160 ? ? OD2 B ASP 220 ? ? 2.12 3 1 O B SER 286 ? ? N B PHE 290 ? ? 2.15 4 1 O A GLY 264 ? ? OG A SER 268 ? ? 2.16 5 1 OG1 B THR 462 ? ? OE1 B GLN 472 ? ? 2.17 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 PHE A 74 ? ? -113.01 59.10 2 1 ASP A 75 ? ? 128.39 29.89 3 1 ASN A 107 ? ? -156.01 -158.73 4 1 ASP A 109 ? ? -63.70 -71.34 5 1 GLU A 138 ? ? 58.44 -128.52 6 1 TYR A 160 ? ? -87.69 -108.97 7 1 ASN A 191 ? ? -144.85 48.86 8 1 ALA A 217 ? ? -157.04 -157.37 9 1 VAL A 232 ? ? -140.87 41.10 10 1 LYS A 240 ? ? -117.09 -155.06 11 1 VAL A 277 ? ? -14.90 -56.79 12 1 GLU A 278 ? ? 158.98 45.26 13 1 ASP A 303 ? ? -112.29 66.55 14 1 LYS A 310 ? ? 61.39 -2.70 15 1 ASN A 404 ? ? -161.78 98.74 16 1 GLU A 406 ? ? -150.38 61.54 17 1 MET A 434 ? ? -80.50 34.04 18 1 ASN A 447 ? ? 58.75 -150.23 19 1 ASN B 63 ? ? 57.06 71.26 20 1 ASP B 109 ? ? -74.95 -72.57 21 1 GLU B 138 ? ? 59.71 -129.67 22 1 TYR B 160 ? ? -100.44 -109.17 23 1 ASN B 191 ? ? -144.31 48.72 24 1 ALA B 217 ? ? -151.88 -146.51 25 1 VAL B 225 ? ? -140.40 -8.19 26 1 SER B 231 ? ? 64.42 -1.52 27 1 VAL B 232 ? ? -141.07 46.81 28 1 LYS B 240 ? ? -119.79 -148.05 29 1 ASP B 303 ? ? -110.46 58.77 30 1 LYS B 310 ? ? 68.42 -2.69 31 1 VAL B 363 ? ? -66.11 -75.50 32 1 SER B 380 ? ? -92.89 59.72 33 1 GLU B 406 ? ? -146.35 57.80 34 1 MET B 434 ? ? -83.42 30.61 35 1 ASN B 444 ? ? 56.43 76.05 36 1 ASN B 447 ? ? 58.72 -152.39 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 ARG _pdbx_validate_peptide_omega.auth_asym_id_1 A _pdbx_validate_peptide_omega.auth_seq_id_1 519 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 ASN _pdbx_validate_peptide_omega.auth_asym_id_2 A _pdbx_validate_peptide_omega.auth_seq_id_2 520 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega 142.47 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A MET 1 ? A MET 1 2 1 Y 1 A LEU 2 ? A LEU 2 3 1 Y 1 A TYR 3 ? A TYR 3 4 1 Y 1 A LYS 4 ? A LYS 4 5 1 Y 1 A LEU 5 ? A LEU 5 6 1 Y 1 A LEU 6 ? A LEU 6 7 1 Y 1 A ASN 7 ? A ASN 7 8 1 Y 1 A VAL 8 ? A VAL 8 9 1 Y 1 A LEU 9 ? A LEU 9 10 1 Y 1 A TRP 10 ? A TRP 10 11 1 Y 1 A LEU 11 ? A LEU 11 12 1 Y 1 A VAL 12 ? A VAL 12 13 1 Y 1 A ALA 13 ? A ALA 13 14 1 Y 1 A VAL 14 ? A VAL 14 15 1 Y 1 A SER 15 ? A SER 15 16 1 Y 1 A ASN 16 ? A ASN 16 17 1 Y 1 A ALA 17 ? A ALA 17 18 1 Y 1 B MET 1 ? B MET 1 19 1 Y 1 B LEU 2 ? B LEU 2 20 1 Y 1 B TYR 3 ? B TYR 3 21 1 Y 1 B LYS 4 ? B LYS 4 22 1 Y 1 B LEU 5 ? B LEU 5 23 1 Y 1 B LEU 6 ? B LEU 6 24 1 Y 1 B ASN 7 ? B ASN 7 25 1 Y 1 B VAL 8 ? B VAL 8 26 1 Y 1 B LEU 9 ? B LEU 9 27 1 Y 1 B TRP 10 ? B TRP 10 28 1 Y 1 B LEU 11 ? B LEU 11 29 1 Y 1 B VAL 12 ? B VAL 12 30 1 Y 1 B ALA 13 ? B ALA 13 31 1 Y 1 B VAL 14 ? B VAL 14 32 1 Y 1 B SER 15 ? B SER 15 33 1 Y 1 B ASN 16 ? B ASN 16 34 1 Y 1 B ALA 17 ? B ALA 17 # _pdbx_audit_support.funding_organization 'National Institutes of Health/National Institute of General Medical Sciences' _pdbx_audit_support.country 'United States' _pdbx_audit_support.grant_number P20GM103546 _pdbx_audit_support.ordinal 1 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 '2-deoxy-2-(ethanethioylamino)-beta-D-glucopyranose' SN5 4 '(2R,3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methylhexahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol' 58Y 5 'CHLORIDE ION' CL 6 'SULFATE ION' SO4 7 water HOH #