data_5CNJ # _entry.id 5CNJ # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 5CNJ WWPDB D_1000211904 # _pdbx_database_related.content_type unspecified _pdbx_database_related.db_id 5CNI _pdbx_database_related.db_name PDB _pdbx_database_related.details . # _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.entry_id 5CNJ _pdbx_database_status.recvd_initial_deposition_date 2015-07-17 _pdbx_database_status.SG_entry N _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Monn, J.A.' 1 'Clawson, D.K.' 2 # _citation.abstract ? _citation.abstract_id_CAS ? _citation.book_id_ISBN ? _citation.book_publisher ? _citation.book_publisher_city ? _citation.book_title ? _citation.coordinate_linkage ? _citation.country US _citation.database_id_Medline ? _citation.details ? _citation.id primary _citation.journal_abbrev J.Med.Chem. _citation.journal_id_ASTM JMCMAR _citation.journal_id_CSD 0151 _citation.journal_id_ISSN 0022-2623 _citation.journal_full ? _citation.journal_issue ? _citation.journal_volume 58 _citation.language ? _citation.page_first 7526 _citation.page_last 7548 _citation.title ;Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist. ; _citation.year 2015 _citation.database_id_CSD ? _citation.pdbx_database_id_DOI 10.1021/acs.jmedchem.5b01124 _citation.pdbx_database_id_PubMed 26313429 _citation.unpublished_flag ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Monn, J.A.' 1 primary 'Prieto, L.' 2 primary 'Taboada, L.' 3 primary 'Hao, J.' 4 primary 'Reinhard, M.R.' 5 primary 'Henry, S.S.' 6 primary 'Beadle, C.D.' 7 primary 'Walton, L.' 8 primary 'Man, T.' 9 primary 'Rudyk, H.' 10 primary 'Clark, B.' 11 primary 'Tupper, D.' 12 primary 'Baker, S.R.' 13 primary 'Lamas, C.' 14 primary 'Montero, C.' 15 primary 'Marcos, A.' 16 primary 'Blanco, J.' 17 primary 'Bures, M.' 18 primary 'Clawson, D.K.' 19 primary 'Atwell, S.' 20 primary 'Lu, F.' 21 primary 'Wang, J.' 22 primary 'Russell, M.' 23 primary 'Heinz, B.A.' 24 primary 'Wang, X.' 25 primary 'Carter, J.H.' 26 primary 'Getman, B.G.' 27 primary 'Catlow, J.T.' 28 primary 'Swanson, S.' 29 primary 'Johnson, B.G.' 30 primary 'Shaw, D.B.' 31 primary 'McKinzie, D.L.' 32 # _cell.angle_alpha 90.00 _cell.angle_alpha_esd ? _cell.angle_beta 90.00 _cell.angle_beta_esd ? _cell.angle_gamma 90.00 _cell.angle_gamma_esd ? _cell.entry_id 5CNJ _cell.details ? _cell.formula_units_Z ? _cell.length_a 80.391 _cell.length_a_esd ? _cell.length_b 155.087 _cell.length_b_esd ? _cell.length_c 92.714 _cell.length_c_esd ? _cell.volume ? _cell.volume_esd ? _cell.Z_PDB 8 _cell.reciprocal_angle_alpha ? _cell.reciprocal_angle_beta ? _cell.reciprocal_angle_gamma ? _cell.reciprocal_angle_alpha_esd ? _cell.reciprocal_angle_beta_esd ? _cell.reciprocal_angle_gamma_esd ? _cell.reciprocal_length_a ? _cell.reciprocal_length_b ? _cell.reciprocal_length_c ? _cell.reciprocal_length_a_esd ? _cell.reciprocal_length_b_esd ? _cell.reciprocal_length_c_esd ? _cell.pdbx_unique_axis ? # _symmetry.entry_id 5CNJ _symmetry.cell_setting ? _symmetry.Int_Tables_number 18 _symmetry.space_group_name_Hall ? _symmetry.space_group_name_H-M 'P 21 21 2' _symmetry.pdbx_full_space_group_name_H-M ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Metabotropic glutamate receptor 2' 55670.797 2 ? ? 'UNP residues 2-493' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 non-polymer syn '(1R,2S,4R,5R,6R)-2-amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid' 284.292 2 ? ? ? ? 4 water nat water 18.015 147 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name mGluR2 # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;MALGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHL LPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLF QIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNISVATS EKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIE LASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRA LCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGL TLDTSLIPWASPSAGEGHHHHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;MALGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHL LPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLF QIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNISVATS EKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIE LASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRA LCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGL TLDTSLIPWASPSAGEGHHHHHH ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 MET n 1 2 ALA n 1 3 LEU n 1 4 GLY n 1 5 SER n 1 6 LEU n 1 7 LEU n 1 8 ALA n 1 9 LEU n 1 10 LEU n 1 11 ALA n 1 12 LEU n 1 13 LEU n 1 14 LEU n 1 15 LEU n 1 16 TRP n 1 17 GLY n 1 18 ALA n 1 19 VAL n 1 20 ALA n 1 21 GLU n 1 22 GLY n 1 23 PRO n 1 24 ALA n 1 25 LYS n 1 26 LYS n 1 27 VAL n 1 28 LEU n 1 29 THR n 1 30 LEU n 1 31 GLU n 1 32 GLY n 1 33 ASP n 1 34 LEU n 1 35 VAL n 1 36 LEU n 1 37 GLY n 1 38 GLY n 1 39 LEU n 1 40 PHE n 1 41 PRO n 1 42 VAL n 1 43 HIS n 1 44 GLN n 1 45 LYS n 1 46 GLY n 1 47 GLY n 1 48 PRO n 1 49 ALA n 1 50 GLU n 1 51 ASP n 1 52 CYS n 1 53 GLY n 1 54 PRO n 1 55 VAL n 1 56 ASN n 1 57 GLU n 1 58 HIS n 1 59 ARG n 1 60 GLY n 1 61 ILE n 1 62 GLN n 1 63 ARG n 1 64 LEU n 1 65 GLU n 1 66 ALA n 1 67 MET n 1 68 LEU n 1 69 PHE n 1 70 ALA n 1 71 LEU n 1 72 ASP n 1 73 ARG n 1 74 ILE n 1 75 ASN n 1 76 ARG n 1 77 ASP n 1 78 PRO n 1 79 HIS n 1 80 LEU n 1 81 LEU n 1 82 PRO n 1 83 GLY n 1 84 VAL n 1 85 ARG n 1 86 LEU n 1 87 GLY n 1 88 ALA n 1 89 HIS n 1 90 ILE n 1 91 LEU n 1 92 ASP n 1 93 SER n 1 94 CYS n 1 95 SER n 1 96 LYS n 1 97 ASP n 1 98 THR n 1 99 HIS n 1 100 ALA n 1 101 LEU n 1 102 GLU n 1 103 GLN n 1 104 ALA n 1 105 LEU n 1 106 ASP n 1 107 PHE n 1 108 VAL n 1 109 ARG n 1 110 ALA n 1 111 SER n 1 112 LEU n 1 113 SER n 1 114 ARG n 1 115 GLY n 1 116 ALA n 1 117 ASP n 1 118 GLY n 1 119 SER n 1 120 ARG n 1 121 HIS n 1 122 ILE n 1 123 CYS n 1 124 PRO n 1 125 ASP n 1 126 GLY n 1 127 SER n 1 128 TYR n 1 129 ALA n 1 130 THR n 1 131 HIS n 1 132 GLY n 1 133 ASP n 1 134 ALA n 1 135 PRO n 1 136 THR n 1 137 ALA n 1 138 ILE n 1 139 THR n 1 140 GLY n 1 141 VAL n 1 142 ILE n 1 143 GLY n 1 144 GLY n 1 145 SER n 1 146 TYR n 1 147 SER n 1 148 ASP n 1 149 VAL n 1 150 SER n 1 151 ILE n 1 152 GLN n 1 153 VAL n 1 154 ALA n 1 155 ASN n 1 156 LEU n 1 157 LEU n 1 158 ARG n 1 159 LEU n 1 160 PHE n 1 161 GLN n 1 162 ILE n 1 163 PRO n 1 164 GLN n 1 165 ILE n 1 166 SER n 1 167 TYR n 1 168 ALA n 1 169 SER n 1 170 THR n 1 171 SER n 1 172 ALA n 1 173 LYS n 1 174 LEU n 1 175 SER n 1 176 ASP n 1 177 LYS n 1 178 SER n 1 179 ARG n 1 180 TYR n 1 181 ASP n 1 182 TYR n 1 183 PHE n 1 184 ALA n 1 185 ARG n 1 186 THR n 1 187 VAL n 1 188 PRO n 1 189 PRO n 1 190 ASP n 1 191 PHE n 1 192 PHE n 1 193 GLN n 1 194 ALA n 1 195 LYS n 1 196 ALA n 1 197 MET n 1 198 ALA n 1 199 GLU n 1 200 ILE n 1 201 LEU n 1 202 ARG n 1 203 PHE n 1 204 PHE n 1 205 ASN n 1 206 TRP n 1 207 THR n 1 208 TYR n 1 209 VAL n 1 210 SER n 1 211 THR n 1 212 VAL n 1 213 ALA n 1 214 SER n 1 215 GLU n 1 216 GLY n 1 217 ASP n 1 218 TYR n 1 219 GLY n 1 220 GLU n 1 221 THR n 1 222 GLY n 1 223 ILE n 1 224 GLU n 1 225 ALA n 1 226 PHE n 1 227 GLU n 1 228 LEU n 1 229 GLU n 1 230 ALA n 1 231 ARG n 1 232 ALA n 1 233 ARG n 1 234 ASN n 1 235 ILE n 1 236 SER n 1 237 VAL n 1 238 ALA n 1 239 THR n 1 240 SER n 1 241 GLU n 1 242 LYS n 1 243 VAL n 1 244 GLY n 1 245 ARG n 1 246 ALA n 1 247 MET n 1 248 SER n 1 249 ARG n 1 250 ALA n 1 251 ALA n 1 252 PHE n 1 253 GLU n 1 254 GLY n 1 255 VAL n 1 256 VAL n 1 257 ARG n 1 258 ALA n 1 259 LEU n 1 260 LEU n 1 261 GLN n 1 262 LYS n 1 263 PRO n 1 264 SER n 1 265 ALA n 1 266 ARG n 1 267 VAL n 1 268 ALA n 1 269 VAL n 1 270 LEU n 1 271 PHE n 1 272 THR n 1 273 ARG n 1 274 SER n 1 275 GLU n 1 276 ASP n 1 277 ALA n 1 278 ARG n 1 279 GLU n 1 280 LEU n 1 281 LEU n 1 282 ALA n 1 283 ALA n 1 284 SER n 1 285 GLN n 1 286 ARG n 1 287 LEU n 1 288 ASN n 1 289 ALA n 1 290 SER n 1 291 PHE n 1 292 THR n 1 293 TRP n 1 294 VAL n 1 295 ALA n 1 296 SER n 1 297 ASP n 1 298 GLY n 1 299 TRP n 1 300 GLY n 1 301 ALA n 1 302 LEU n 1 303 GLU n 1 304 SER n 1 305 VAL n 1 306 VAL n 1 307 ALA n 1 308 GLY n 1 309 SER n 1 310 GLU n 1 311 GLY n 1 312 ALA n 1 313 ALA n 1 314 GLU n 1 315 GLY n 1 316 ALA n 1 317 ILE n 1 318 THR n 1 319 ILE n 1 320 GLU n 1 321 LEU n 1 322 ALA n 1 323 SER n 1 324 TYR n 1 325 PRO n 1 326 ILE n 1 327 SER n 1 328 ASP n 1 329 PHE n 1 330 ALA n 1 331 SER n 1 332 TYR n 1 333 PHE n 1 334 GLN n 1 335 SER n 1 336 LEU n 1 337 ASP n 1 338 PRO n 1 339 TRP n 1 340 ASN n 1 341 ASN n 1 342 SER n 1 343 ARG n 1 344 ASN n 1 345 PRO n 1 346 TRP n 1 347 PHE n 1 348 ARG n 1 349 GLU n 1 350 PHE n 1 351 TRP n 1 352 GLU n 1 353 GLN n 1 354 ARG n 1 355 PHE n 1 356 ARG n 1 357 CYS n 1 358 SER n 1 359 PHE n 1 360 ARG n 1 361 GLN n 1 362 ARG n 1 363 ASP n 1 364 CYS n 1 365 ALA n 1 366 ALA n 1 367 HIS n 1 368 SER n 1 369 LEU n 1 370 ARG n 1 371 ALA n 1 372 VAL n 1 373 PRO n 1 374 PHE n 1 375 GLU n 1 376 GLN n 1 377 GLU n 1 378 SER n 1 379 LYS n 1 380 ILE n 1 381 MET n 1 382 PHE n 1 383 VAL n 1 384 VAL n 1 385 ASN n 1 386 ALA n 1 387 VAL n 1 388 TYR n 1 389 ALA n 1 390 MET n 1 391 ALA n 1 392 HIS n 1 393 ALA n 1 394 LEU n 1 395 HIS n 1 396 ASN n 1 397 MET n 1 398 HIS n 1 399 ARG n 1 400 ALA n 1 401 LEU n 1 402 CYS n 1 403 PRO n 1 404 ASN n 1 405 THR n 1 406 THR n 1 407 ARG n 1 408 LEU n 1 409 CYS n 1 410 ASP n 1 411 ALA n 1 412 MET n 1 413 ARG n 1 414 PRO n 1 415 VAL n 1 416 ASN n 1 417 GLY n 1 418 ARG n 1 419 ARG n 1 420 LEU n 1 421 TYR n 1 422 LYS n 1 423 ASP n 1 424 PHE n 1 425 VAL n 1 426 LEU n 1 427 ASN n 1 428 VAL n 1 429 LYS n 1 430 PHE n 1 431 ASP n 1 432 ALA n 1 433 PRO n 1 434 PHE n 1 435 ARG n 1 436 PRO n 1 437 ALA n 1 438 ASP n 1 439 THR n 1 440 HIS n 1 441 ASN n 1 442 GLU n 1 443 VAL n 1 444 ARG n 1 445 PHE n 1 446 ASP n 1 447 ARG n 1 448 PHE n 1 449 GLY n 1 450 ASP n 1 451 GLY n 1 452 ILE n 1 453 GLY n 1 454 ARG n 1 455 TYR n 1 456 ASN n 1 457 ILE n 1 458 PHE n 1 459 THR n 1 460 TYR n 1 461 LEU n 1 462 ARG n 1 463 ALA n 1 464 GLY n 1 465 SER n 1 466 GLY n 1 467 ARG n 1 468 TYR n 1 469 ARG n 1 470 TYR n 1 471 GLN n 1 472 LYS n 1 473 VAL n 1 474 GLY n 1 475 TYR n 1 476 TRP n 1 477 ALA n 1 478 GLU n 1 479 GLY n 1 480 LEU n 1 481 THR n 1 482 LEU n 1 483 ASP n 1 484 THR n 1 485 SER n 1 486 LEU n 1 487 ILE n 1 488 PRO n 1 489 TRP n 1 490 ALA n 1 491 SER n 1 492 PRO n 1 493 SER n 1 494 ALA n 1 495 GLY n 1 496 GLU n 1 497 GLY n 1 498 HIS n 1 499 HIS n 1 500 HIS n 1 501 HIS n 1 502 HIS n 1 503 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type 'Biological sequence' _entity_src_gen.pdbx_beg_seq_num 1 _entity_src_gen.pdbx_end_seq_num 503 _entity_src_gen.gene_src_common_name Human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'GRM2, GPRC1B, MGLUR2' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'fall armyworm' _entity_src_gen.pdbx_host_org_scientific_name 'Spodoptera frugiperda' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7108 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line SF9 _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type BACULOVIRUS _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code GRM2_HUMAN _struct_ref.pdbx_db_accession Q14416 _struct_ref.pdbx_db_isoform ? _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;GSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPG VRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIP QISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKV GRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELAS YPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCP NTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLD TSLIPWASPSAG ; _struct_ref.pdbx_align_begin 2 # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 5CNJ A 4 ? 495 ? Q14416 2 ? 493 ? 2 493 2 1 5CNJ B 4 ? 495 ? Q14416 2 ? 493 ? 2 493 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 5CNJ MET A 1 ? UNP Q14416 ? ? 'expression tag' -1 1 1 5CNJ ALA A 2 ? UNP Q14416 ? ? 'expression tag' 0 2 1 5CNJ LEU A 3 ? UNP Q14416 ? ? 'expression tag' 1 3 1 5CNJ SER A 236 ? UNP Q14416 CYS 234 conflict 234 4 1 5CNJ GLU A 496 ? UNP Q14416 ? ? 'expression tag' 494 5 1 5CNJ GLY A 497 ? UNP Q14416 ? ? 'expression tag' 495 6 1 5CNJ HIS A 498 ? UNP Q14416 ? ? 'expression tag' 496 7 1 5CNJ HIS A 499 ? UNP Q14416 ? ? 'expression tag' 497 8 1 5CNJ HIS A 500 ? UNP Q14416 ? ? 'expression tag' 498 9 1 5CNJ HIS A 501 ? UNP Q14416 ? ? 'expression tag' 499 10 1 5CNJ HIS A 502 ? UNP Q14416 ? ? 'expression tag' 500 11 1 5CNJ HIS A 503 ? UNP Q14416 ? ? 'expression tag' 501 12 2 5CNJ MET B 1 ? UNP Q14416 ? ? 'expression tag' -1 13 2 5CNJ ALA B 2 ? UNP Q14416 ? ? 'expression tag' 0 14 2 5CNJ LEU B 3 ? UNP Q14416 ? ? 'expression tag' 1 15 2 5CNJ SER B 236 ? UNP Q14416 CYS 234 conflict 234 16 2 5CNJ GLU B 496 ? UNP Q14416 ? ? 'expression tag' 494 17 2 5CNJ GLY B 497 ? UNP Q14416 ? ? 'expression tag' 495 18 2 5CNJ HIS B 498 ? UNP Q14416 ? ? 'expression tag' 496 19 2 5CNJ HIS B 499 ? UNP Q14416 ? ? 'expression tag' 497 20 2 5CNJ HIS B 500 ? UNP Q14416 ? ? 'expression tag' 498 21 2 5CNJ HIS B 501 ? UNP Q14416 ? ? 'expression tag' 499 22 2 5CNJ HIS B 502 ? UNP Q14416 ? ? 'expression tag' 500 23 2 5CNJ HIS B 503 ? UNP Q14416 ? ? 'expression tag' 501 24 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight 52Q non-polymer . '(1R,2S,4R,5R,6R)-2-amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid' ? 'C10 H12 N4 O4 S' 284.292 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.absorpt_coefficient_mu ? _exptl.absorpt_correction_T_max ? _exptl.absorpt_correction_T_min ? _exptl.absorpt_correction_type ? _exptl.absorpt_process_details ? _exptl.entry_id 5CNJ _exptl.crystals_number ? _exptl.details ? _exptl.method 'X-RAY DIFFRACTION' _exptl.method_details ? # _exptl_crystal.colour ? _exptl_crystal.density_diffrn ? _exptl_crystal.density_Matthews 2.74 _exptl_crystal.density_method ? _exptl_crystal.density_percent_sol 55.12 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.id 1 _exptl_crystal.preparation ? _exptl_crystal.size_max ? _exptl_crystal.size_mid ? _exptl_crystal.size_min ? _exptl_crystal.size_rad ? _exptl_crystal.colour_lustre ? _exptl_crystal.colour_modifier ? _exptl_crystal.colour_primary ? _exptl_crystal.density_meas ? _exptl_crystal.density_meas_esd ? _exptl_crystal.density_meas_gt ? _exptl_crystal.density_meas_lt ? _exptl_crystal.density_meas_temp ? _exptl_crystal.density_meas_temp_esd ? _exptl_crystal.density_meas_temp_gt ? _exptl_crystal.density_meas_temp_lt ? _exptl_crystal.pdbx_crystal_image_url ? _exptl_crystal.pdbx_crystal_image_format ? _exptl_crystal.pdbx_mosaicity ? _exptl_crystal.pdbx_mosaicity_esd ? # _exptl_crystal_grow.apparatus ? _exptl_crystal_grow.atmosphere ? _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.details ? _exptl_crystal_grow.method 'VAPOR DIFFUSION' _exptl_crystal_grow.method_ref ? _exptl_crystal_grow.pH ? _exptl_crystal_grow.pressure ? _exptl_crystal_grow.pressure_esd ? _exptl_crystal_grow.seeding ? _exptl_crystal_grow.seeding_ref ? _exptl_crystal_grow.temp 295 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.temp_esd ? _exptl_crystal_grow.time ? _exptl_crystal_grow.pdbx_details '100mM Hepes pH 7 + 20% PEG 3350 + 200mM Magnesium Chloride' _exptl_crystal_grow.pdbx_pH_range 7 # _diffrn.ambient_environment ? _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.ambient_temp_esd ? _diffrn.crystal_id 1 _diffrn.crystal_support ? _diffrn.crystal_treatment ? _diffrn.details ? _diffrn.id 1 _diffrn.ambient_pressure ? _diffrn.ambient_pressure_esd ? _diffrn.ambient_pressure_gt ? _diffrn.ambient_pressure_lt ? _diffrn.ambient_temp_gt ? _diffrn.ambient_temp_lt ? # _diffrn_detector.details ? _diffrn_detector.detector CCD _diffrn_detector.diffrn_id 1 _diffrn_detector.type 'RAYONIX MX225HE' _diffrn_detector.area_resol_mean ? _diffrn_detector.dtime ? _diffrn_detector.pdbx_frames_total ? _diffrn_detector.pdbx_collection_time_total ? _diffrn_detector.pdbx_collection_date 2011-01-18 # _diffrn_radiation.collimation ? _diffrn_radiation.diffrn_id 1 _diffrn_radiation.filter_edge ? _diffrn_radiation.inhomogeneity ? _diffrn_radiation.monochromator ? _diffrn_radiation.polarisn_norm ? _diffrn_radiation.polarisn_ratio ? _diffrn_radiation.probe ? _diffrn_radiation.type ? _diffrn_radiation.xray_symbol ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_wavelength_list ? _diffrn_radiation.pdbx_wavelength ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_analyzer ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.97931 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.current ? _diffrn_source.details ? _diffrn_source.diffrn_id 1 _diffrn_source.power ? _diffrn_source.size ? _diffrn_source.source SYNCHROTRON _diffrn_source.target ? _diffrn_source.type 'APS BEAMLINE 31-ID' _diffrn_source.voltage ? _diffrn_source.take-off_angle ? _diffrn_source.pdbx_wavelength_list 0.97931 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_beamline 31-ID _diffrn_source.pdbx_synchrotron_site APS # _reflns.B_iso_Wilson_estimate 64.77 _reflns.entry_id 5CNJ _reflns.data_reduction_details ? _reflns.data_reduction_method ? _reflns.d_resolution_high 2.65 _reflns.d_resolution_low 28.04 _reflns.details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.number_all ? _reflns.number_obs 33677 _reflns.observed_criterion ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.observed_criterion_I_max ? _reflns.observed_criterion_I_min ? _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I ? _reflns.percent_possible_obs 97.94 _reflns.R_free_details ? _reflns.Rmerge_F_all ? _reflns.Rmerge_F_obs ? _reflns.Friedel_coverage ? _reflns.number_gt ? _reflns.threshold_expression ? _reflns.pdbx_redundancy 6.4 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rmerge_I_all ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_av_sigmaI ? _reflns.pdbx_netI_over_sigmaI 7.6 _reflns.pdbx_res_netI_over_av_sigmaI_2 ? _reflns.pdbx_res_netI_over_sigmaI_2 ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_d_res_high_opt ? _reflns.pdbx_d_res_low_opt ? _reflns.pdbx_d_res_opt_method ? _reflns.phase_calculation_details ? _reflns.pdbx_Rrim_I_all ? _reflns.pdbx_Rpim_I_all ? _reflns.pdbx_d_opt ? _reflns.pdbx_number_measured_all ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 _reflns.pdbx_CC_half ? _reflns.pdbx_R_split ? # _refine.aniso_B[1][1] 1.6614 _refine.aniso_B[1][2] 0.0000 _refine.aniso_B[1][3] 0.0000 _refine.aniso_B[2][2] -16.8838 _refine.aniso_B[2][3] 0.0000 _refine.aniso_B[3][3] 15.2224 _refine.B_iso_max ? _refine.B_iso_mean 57.68 _refine.B_iso_min ? _refine.correlation_coeff_Fo_to_Fc 0.9124 _refine.correlation_coeff_Fo_to_Fc_free 0.8841 _refine.details ? _refine.diff_density_max ? _refine.diff_density_max_esd ? _refine.diff_density_min ? _refine.diff_density_min_esd ? _refine.diff_density_rms ? _refine.diff_density_rms_esd ? _refine.entry_id 5CNJ _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.ls_abs_structure_details ? _refine.ls_abs_structure_Flack ? _refine.ls_abs_structure_Flack_esd ? _refine.ls_abs_structure_Rogers ? _refine.ls_abs_structure_Rogers_esd ? _refine.ls_d_res_high 2.65 _refine.ls_d_res_low 28.04 _refine.ls_extinction_coef ? _refine.ls_extinction_coef_esd ? _refine.ls_extinction_expression ? _refine.ls_extinction_method ? _refine.ls_goodness_of_fit_all ? _refine.ls_goodness_of_fit_all_esd ? _refine.ls_goodness_of_fit_obs ? _refine.ls_goodness_of_fit_obs_esd ? _refine.ls_hydrogen_treatment ? _refine.ls_matrix_type ? _refine.ls_number_constraints ? _refine.ls_number_parameters ? _refine.ls_number_reflns_all ? _refine.ls_number_reflns_obs 33677 _refine.ls_number_reflns_R_free 1005 _refine.ls_number_reflns_R_work ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_obs 97.94 _refine.ls_percent_reflns_R_free 2.98 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.1945 _refine.ls_R_factor_R_free 0.2412 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_R_factor_R_work 0.1930 _refine.ls_R_Fsqd_factor_obs ? _refine.ls_R_I_factor_obs ? _refine.ls_redundancy_reflns_all ? _refine.ls_redundancy_reflns_obs ? _refine.ls_restrained_S_all ? _refine.ls_restrained_S_obs ? _refine.ls_shift_over_esd_max ? _refine.ls_shift_over_esd_mean ? _refine.ls_structure_factor_coef ? _refine.ls_weighting_details ? _refine.ls_weighting_scheme ? _refine.ls_wR_factor_all ? _refine.ls_wR_factor_obs ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.solvent_model_details ? _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.ls_R_factor_gt ? _refine.ls_goodness_of_fit_gt ? _refine.ls_goodness_of_fit_ref ? _refine.ls_shift_over_su_max ? _refine.ls_shift_over_su_max_lt ? _refine.ls_shift_over_su_mean ? _refine.ls_shift_over_su_mean_lt ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.0 _refine.pdbx_ls_sigma_Fsqd ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_method_to_determine_struct ? _refine.pdbx_starting_model ? _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_real_space_R ? _refine.pdbx_density_correlation ? _refine.pdbx_pd_number_of_powder_patterns ? _refine.pdbx_pd_number_of_points ? _refine.pdbx_pd_meas_number_of_points ? _refine.pdbx_pd_proc_ls_prof_R_factor ? _refine.pdbx_pd_proc_ls_prof_wR_factor ? _refine.pdbx_pd_Marquardt_correlation_coeff ? _refine.pdbx_pd_Fsqrd_R_factor ? _refine.pdbx_pd_ls_matrix_band_width ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI 0.297 _refine.pdbx_overall_SU_R_free_Blow_DPI 0.293 _refine.pdbx_overall_SU_R_Blow_DPI 0.629 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_diffrn_id 1 _refine.overall_SU_B ? _refine.overall_SU_ML ? _refine.overall_SU_R_Cruickshank_DPI 0.622 _refine.overall_SU_R_free ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_average_fsc_overall ? _refine.pdbx_average_fsc_work ? _refine.pdbx_average_fsc_free ? # _refine_analyze.entry_id 5CNJ _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_analyze.Luzzati_coordinate_error_free ? _refine_analyze.Luzzati_coordinate_error_obs 0.307 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_sigma_a_free ? _refine_analyze.Luzzati_sigma_a_free_details ? _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_sigma_a_obs_details ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.RG_d_res_high ? _refine_analyze.RG_d_res_low ? _refine_analyze.RG_free ? _refine_analyze.RG_work ? _refine_analyze.RG_free_work_ratio ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6991 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 52 _refine_hist.number_atoms_solvent 147 _refine_hist.number_atoms_total 7190 _refine_hist.d_res_high 2.65 _refine_hist.d_res_low 28.04 # loop_ _refine_ls_restr.pdbx_refine_id _refine_ls_restr.criterion _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.number _refine_ls_restr.rejects _refine_ls_restr.type _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function 'X-RAY DIFFRACTION' ? 0.010 ? 7223 ? t_bond_d 2.00 HARMONIC 'X-RAY DIFFRACTION' ? 1.12 ? 9806 ? t_angle_deg 2.00 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 2449 ? t_dihedral_angle_d 2.00 SINUSOIDAL 'X-RAY DIFFRACTION' ? ? ? ? ? t_incorr_chiral_ct ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_pseud_angle ? ? 'X-RAY DIFFRACTION' ? ? ? 158 ? t_trig_c_planes 2.00 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 1090 ? t_gen_planes 5.00 HARMONIC 'X-RAY DIFFRACTION' ? ? ? 7223 ? t_it 20.00 HARMONIC 'X-RAY DIFFRACTION' ? ? ? ? ? t_nbd ? ? 'X-RAY DIFFRACTION' ? 3.01 ? ? ? t_omega_torsion ? ? 'X-RAY DIFFRACTION' ? 19.12 ? ? ? t_other_torsion ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_improper_torsion ? ? 'X-RAY DIFFRACTION' ? ? ? 918 ? t_chiral_improper_torsion 5.00 SEMIHARMONIC 'X-RAY DIFFRACTION' ? ? ? ? ? t_sum_occupancies ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_utility_distance ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_utility_angle ? ? 'X-RAY DIFFRACTION' ? ? ? ? ? t_utility_torsion ? ? 'X-RAY DIFFRACTION' ? ? ? 8326 ? t_ideal_dist_contact 4.00 SEMIHARMONIC # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.d_res_high 2.65 _refine_ls_shell.d_res_low 2.73 _refine_ls_shell.number_reflns_all 2778 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.number_reflns_R_free 79 _refine_ls_shell.number_reflns_R_work 2699 _refine_ls_shell.percent_reflns_obs 97.94 _refine_ls_shell.percent_reflns_R_free 2.84 _refine_ls_shell.R_factor_all 0.2267 _refine_ls_shell.R_factor_obs ? _refine_ls_shell.R_factor_R_free 0.3226 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.R_factor_R_work 0.2241 _refine_ls_shell.redundancy_reflns_all ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.wR_factor_all ? _refine_ls_shell.wR_factor_obs ? _refine_ls_shell.wR_factor_R_free ? _refine_ls_shell.wR_factor_R_work ? _refine_ls_shell.pdbx_total_number_of_bins_used 17 _refine_ls_shell.pdbx_phase_error ? _refine_ls_shell.pdbx_fsc_work ? _refine_ls_shell.pdbx_fsc_free ? # _struct.entry_id 5CNJ _struct.title 'mGlur2 with glutamate analog' _struct.pdbx_descriptor 'Metabotropic glutamate receptor 2' _struct.pdbx_model_details ? _struct.pdbx_formula_weight ? _struct.pdbx_formula_weight_method ? _struct.pdbx_model_type_details ? _struct.pdbx_CASP_flag ? # _struct_keywords.entry_id 5CNJ _struct_keywords.text 'glutamate receptor analog, SIGNALING PROTEIN' _struct_keywords.pdbx_keywords 'SIGNALING PROTEIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 3 ? F N N 4 ? G N N 4 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 AA1 GLY A 60 ? ASN A 75 ? GLY A 58 ASN A 73 1 ? 16 HELX_P HELX_P2 AA2 LYS A 96 ? ALA A 104 ? LYS A 94 ALA A 102 1 ? 9 HELX_P HELX_P3 AA3 LEU A 105 ? VAL A 108 ? LEU A 103 VAL A 106 5 ? 4 HELX_P HELX_P4 AA4 TYR A 146 ? PHE A 160 ? TYR A 144 PHE A 158 1 ? 15 HELX_P HELX_P5 AA5 SER A 171 ? ASP A 176 ? SER A 169 ASP A 174 5 ? 6 HELX_P HELX_P6 AA6 PRO A 189 ? PHE A 204 ? PRO A 187 PHE A 202 1 ? 16 HELX_P HELX_P7 AA7 TYR A 218 ? ARG A 233 ? TYR A 216 ARG A 231 1 ? 16 HELX_P HELX_P8 AA8 SER A 248 ? GLN A 261 ? SER A 246 GLN A 259 1 ? 14 HELX_P HELX_P9 AA9 ARG A 273 ? LEU A 287 ? ARG A 271 LEU A 285 1 ? 15 HELX_P HELX_P10 AB1 LEU A 302 ? ALA A 307 ? LEU A 300 ALA A 305 1 ? 6 HELX_P HELX_P11 AB2 SER A 309 ? GLU A 314 ? SER A 307 GLU A 312 1 ? 6 HELX_P HELX_P12 AB3 ILE A 326 ? SER A 335 ? ILE A 324 SER A 333 1 ? 10 HELX_P HELX_P13 AB4 TRP A 346 ? PHE A 355 ? TRP A 344 PHE A 353 1 ? 10 HELX_P HELX_P14 AB5 SER A 358 ? ARG A 362 ? SER A 356 ARG A 360 5 ? 5 HELX_P HELX_P15 AB6 LYS A 379 ? CYS A 402 ? LYS A 377 CYS A 400 1 ? 24 HELX_P HELX_P16 AB7 CYS A 409 ? ARG A 413 ? CYS A 407 ARG A 411 5 ? 5 HELX_P HELX_P17 AB8 ASN A 416 ? PHE A 424 ? ASN A 414 PHE A 422 1 ? 9 HELX_P HELX_P18 AB9 VAL A 425 ? ASN A 427 ? VAL A 423 ASN A 425 5 ? 3 HELX_P HELX_P19 AC1 THR A 484 ? ILE A 487 ? THR A 482 ILE A 485 5 ? 4 HELX_P HELX_P20 AC2 GLY B 60 ? ARG B 76 ? GLY B 58 ARG B 74 1 ? 17 HELX_P HELX_P21 AC3 LYS B 96 ? LEU B 105 ? LYS B 94 LEU B 103 1 ? 10 HELX_P HELX_P22 AC4 ASP B 106 ? ARG B 109 ? ASP B 104 ARG B 107 5 ? 4 HELX_P HELX_P23 AC5 TYR B 146 ? ARG B 158 ? TYR B 144 ARG B 156 1 ? 13 HELX_P HELX_P24 AC6 LEU B 159 ? GLN B 161 ? LEU B 157 GLN B 159 5 ? 3 HELX_P HELX_P25 AC7 ALA B 172 ? ASP B 176 ? ALA B 170 ASP B 174 5 ? 5 HELX_P HELX_P26 AC8 PRO B 189 ? PHE B 204 ? PRO B 187 PHE B 202 1 ? 16 HELX_P HELX_P27 AC9 GLY B 216 ? ALA B 232 ? GLY B 214 ALA B 230 1 ? 17 HELX_P HELX_P28 AD1 SER B 248 ? GLN B 261 ? SER B 246 GLN B 259 1 ? 14 HELX_P HELX_P29 AD2 ARG B 273 ? LEU B 287 ? ARG B 271 LEU B 285 1 ? 15 HELX_P HELX_P30 AD3 LEU B 302 ? ALA B 307 ? LEU B 300 ALA B 305 1 ? 6 HELX_P HELX_P31 AD4 SER B 309 ? GLU B 314 ? SER B 307 GLU B 312 1 ? 6 HELX_P HELX_P32 AD5 ILE B 326 ? SER B 335 ? ILE B 324 SER B 333 1 ? 10 HELX_P HELX_P33 AD6 TRP B 346 ? PHE B 355 ? TRP B 344 PHE B 353 1 ? 10 HELX_P HELX_P34 AD7 SER B 368 ? VAL B 372 ? SER B 366 VAL B 370 5 ? 5 HELX_P HELX_P35 AD8 LYS B 379 ? CYS B 402 ? LYS B 377 CYS B 400 1 ? 24 HELX_P HELX_P36 AD9 CYS B 409 ? ARG B 413 ? CYS B 407 ARG B 411 5 ? 5 HELX_P HELX_P37 AE1 ASN B 416 ? PHE B 424 ? ASN B 414 PHE B 422 1 ? 9 HELX_P HELX_P38 AE2 VAL B 425 ? ASN B 427 ? VAL B 423 ASN B 425 5 ? 3 HELX_P HELX_P39 AE3 GLY B 464 ? GLY B 466 ? GLY B 462 GLY B 464 5 ? 3 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 52 SG ? ? ? 1_555 A CYS 94 SG ? ? A CYS 50 A CYS 92 1_555 ? ? ? ? ? ? ? 2.023 ? disulf2 disulf ? ? A CYS 357 SG ? ? ? 1_555 A CYS 364 SG ? ? A CYS 355 A CYS 362 1_555 ? ? ? ? ? ? ? 2.045 ? disulf3 disulf ? ? A CYS 402 SG ? ? ? 1_555 A CYS 409 SG ? ? A CYS 400 A CYS 407 1_555 ? ? ? ? ? ? ? 2.038 ? disulf4 disulf ? ? B CYS 52 SG ? ? ? 1_555 B CYS 94 SG ? ? B CYS 50 B CYS 92 1_555 ? ? ? ? ? ? ? 2.033 ? disulf5 disulf ? ? B CYS 357 SG ? ? ? 1_555 B CYS 364 SG ? ? B CYS 355 B CYS 362 1_555 ? ? ? ? ? ? ? 2.046 ? disulf6 disulf ? ? B CYS 402 SG ? ? ? 1_555 B CYS 409 SG ? ? B CYS 400 B CYS 407 1_555 ? ? ? ? ? ? ? 2.039 ? covale1 covale one ? A ASN 205 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 203 A NAG 601 1_555 ? ? ? ? ? ? ? 1.436 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ARG 413 A . ? ARG 411 A PRO 414 A ? PRO 412 A 1 3.06 2 ARG 413 B . ? ARG 411 B PRO 414 B ? PRO 412 B 1 -0.49 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details AA1 ? 6 ? AA2 ? 2 ? AA3 ? 8 ? AA4 ? 2 ? AA5 ? 6 ? AA6 ? 2 ? AA7 ? 8 ? AA8 ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense AA1 1 2 ? anti-parallel AA1 2 3 ? parallel AA1 3 4 ? parallel AA1 4 5 ? parallel AA1 5 6 ? parallel AA2 1 2 ? anti-parallel AA3 1 2 ? parallel AA3 2 3 ? parallel AA3 3 4 ? parallel AA3 4 5 ? parallel AA3 5 6 ? anti-parallel AA3 6 7 ? anti-parallel AA3 7 8 ? anti-parallel AA4 1 2 ? anti-parallel AA5 1 2 ? anti-parallel AA5 2 3 ? parallel AA5 3 4 ? parallel AA5 4 5 ? parallel AA5 5 6 ? parallel AA6 1 2 ? anti-parallel AA7 1 2 ? parallel AA7 2 3 ? parallel AA7 3 4 ? parallel AA7 4 5 ? parallel AA7 5 6 ? anti-parallel AA7 6 7 ? anti-parallel AA7 7 8 ? anti-parallel AA8 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id AA1 1 LEU A 28 ? LEU A 30 ? LEU A 26 LEU A 28 AA1 2 LEU A 86 ? ASP A 92 ? LEU A 84 ASP A 90 AA1 3 LEU A 34 ? PHE A 40 ? LEU A 32 PHE A 38 AA1 4 ILE A 138 ? GLY A 143 ? ILE A 136 GLY A 141 AA1 5 GLN A 164 ? SER A 166 ? GLN A 162 SER A 164 AA1 6 PHE A 183 ? ARG A 185 ? PHE A 181 ARG A 183 AA2 1 HIS A 43 ? LYS A 45 ? HIS A 41 LYS A 43 AA2 2 CYS A 52 ? VAL A 55 ? CYS A 50 VAL A 53 AA3 1 SER A 236 ? VAL A 243 ? SER A 234 VAL A 241 AA3 2 TYR A 208 ? SER A 214 ? TYR A 206 SER A 212 AA3 3 VAL A 267 ? PHE A 271 ? VAL A 265 PHE A 269 AA3 4 THR A 292 ? ALA A 295 ? THR A 290 ALA A 293 AA3 5 ILE A 317 ? LEU A 321 ? ILE A 315 LEU A 319 AA3 6 ARG A 454 ? ARG A 462 ? ARG A 452 ARG A 460 AA3 7 TYR A 468 ? ALA A 477 ? TYR A 466 ALA A 475 AA3 8 LEU A 480 ? LEU A 482 ? LEU A 478 LEU A 480 AA4 1 LYS A 429 ? ASP A 431 ? LYS A 427 ASP A 429 AA4 2 GLU A 442 ? ARG A 444 ? GLU A 440 ARG A 442 AA5 1 LEU B 28 ? LEU B 30 ? LEU B 26 LEU B 28 AA5 2 LEU B 86 ? ASP B 92 ? LEU B 84 ASP B 90 AA5 3 LEU B 34 ? PHE B 40 ? LEU B 32 PHE B 38 AA5 4 GLY B 140 ? GLY B 143 ? GLY B 138 GLY B 141 AA5 5 GLN B 164 ? SER B 166 ? GLN B 162 SER B 164 AA5 6 PHE B 183 ? ARG B 185 ? PHE B 181 ARG B 183 AA6 1 HIS B 43 ? LYS B 45 ? HIS B 41 LYS B 43 AA6 2 CYS B 52 ? VAL B 55 ? CYS B 50 VAL B 53 AA7 1 SER B 236 ? SER B 240 ? SER B 234 SER B 238 AA7 2 TYR B 208 ? ALA B 213 ? TYR B 206 ALA B 211 AA7 3 VAL B 267 ? PHE B 271 ? VAL B 265 PHE B 269 AA7 4 THR B 292 ? ALA B 295 ? THR B 290 ALA B 293 AA7 5 ILE B 317 ? LEU B 321 ? ILE B 315 LEU B 319 AA7 6 TYR B 455 ? ARG B 462 ? TYR B 453 ARG B 460 AA7 7 TYR B 468 ? TRP B 476 ? TYR B 466 TRP B 474 AA7 8 LEU B 480 ? LEU B 482 ? LEU B 478 LEU B 480 AA8 1 LYS B 429 ? ASP B 431 ? LYS B 427 ASP B 429 AA8 2 GLU B 442 ? ARG B 444 ? GLU B 440 ARG B 442 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id AA1 1 2 N LEU A 28 ? N LEU A 26 O ILE A 90 ? O ILE A 88 AA1 2 3 O GLY A 87 ? O GLY A 85 N LEU A 34 ? N LEU A 32 AA1 3 4 N GLY A 37 ? N GLY A 35 O ILE A 142 ? O ILE A 140 AA1 4 5 N VAL A 141 ? N VAL A 139 O ILE A 165 ? O ILE A 163 AA1 5 6 N GLN A 164 ? N GLN A 162 O ALA A 184 ? O ALA A 182 AA2 1 2 N GLN A 44 ? N GLN A 42 O GLY A 53 ? O GLY A 51 AA3 1 2 O ALA A 238 ? O ALA A 236 N VAL A 209 ? N VAL A 207 AA3 2 3 N SER A 210 ? N SER A 208 O VAL A 269 ? O VAL A 267 AA3 3 4 N LEU A 270 ? N LEU A 268 O VAL A 294 ? O VAL A 292 AA3 4 5 N TRP A 293 ? N TRP A 291 O ILE A 317 ? O ILE A 315 AA3 5 6 N THR A 318 ? N THR A 316 O PHE A 458 ? O PHE A 456 AA3 6 7 N LEU A 461 ? N LEU A 459 O ARG A 469 ? O ARG A 467 AA3 7 8 N TYR A 475 ? N TYR A 473 O THR A 481 ? O THR A 479 AA4 1 2 N PHE A 430 ? N PHE A 428 O VAL A 443 ? O VAL A 441 AA5 1 2 N LEU B 28 ? N LEU B 26 O ILE B 90 ? O ILE B 88 AA5 2 3 O GLY B 87 ? O GLY B 85 N LEU B 34 ? N LEU B 32 AA5 3 4 N GLY B 37 ? N GLY B 35 O ILE B 142 ? O ILE B 140 AA5 4 5 N VAL B 141 ? N VAL B 139 O ILE B 165 ? O ILE B 163 AA5 5 6 N SER B 166 ? N SER B 164 O ALA B 184 ? O ALA B 182 AA6 1 2 N GLN B 44 ? N GLN B 42 O GLY B 53 ? O GLY B 51 AA7 1 2 O ALA B 238 ? O ALA B 236 N VAL B 209 ? N VAL B 207 AA7 2 3 N SER B 210 ? N SER B 208 O VAL B 269 ? O VAL B 267 AA7 3 4 N LEU B 270 ? N LEU B 268 O VAL B 294 ? O VAL B 292 AA7 4 5 N TRP B 293 ? N TRP B 291 O ILE B 317 ? O ILE B 315 AA7 5 6 N GLU B 320 ? N GLU B 318 O ASN B 456 ? O ASN B 454 AA7 6 7 N THR B 459 ? N THR B 457 O GLN B 471 ? O GLN B 469 AA7 7 8 N TYR B 475 ? N TYR B 473 O THR B 481 ? O THR B 479 AA8 1 2 N PHE B 430 ? N PHE B 428 O VAL B 443 ? O VAL B 441 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software A 52Q 602 ? 14 'binding site for residue 52Q A 602' AC2 Software B 52Q 601 ? 15 'binding site for residue 52Q B 601' AC3 Software A NAG 601 ? 3 'binding site for Mono-Saccharide NAG A 601 bound to ASN A 203' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 14 ARG A 59 ? ARG A 57 . ? 1_555 ? 2 AC1 14 ARG A 63 ? ARG A 61 . ? 1_555 ? 3 AC1 14 SER A 145 ? SER A 143 . ? 1_555 ? 4 AC1 14 TYR A 146 ? TYR A 144 . ? 1_555 ? 5 AC1 14 SER A 147 ? SER A 145 . ? 1_555 ? 6 AC1 14 ALA A 168 ? ALA A 166 . ? 1_555 ? 7 AC1 14 SER A 169 ? SER A 167 . ? 1_555 ? 8 AC1 14 THR A 170 ? THR A 168 . ? 1_555 ? 9 AC1 14 ARG A 273 ? ARG A 271 . ? 1_555 ? 10 AC1 14 SER A 274 ? SER A 272 . ? 1_555 ? 11 AC1 14 GLU A 275 ? GLU A 273 . ? 1_555 ? 12 AC1 14 ASP A 297 ? ASP A 295 . ? 1_555 ? 13 AC1 14 LYS A 379 ? LYS A 377 . ? 1_555 ? 14 AC1 14 HOH F . ? HOH A 755 . ? 1_555 ? 15 AC2 15 ARG B 59 ? ARG B 57 . ? 1_555 ? 16 AC2 15 ARG B 63 ? ARG B 61 . ? 1_555 ? 17 AC2 15 SER B 145 ? SER B 143 . ? 1_555 ? 18 AC2 15 TYR B 146 ? TYR B 144 . ? 1_555 ? 19 AC2 15 SER B 147 ? SER B 145 . ? 1_555 ? 20 AC2 15 ALA B 168 ? ALA B 166 . ? 1_555 ? 21 AC2 15 SER B 169 ? SER B 167 . ? 1_555 ? 22 AC2 15 THR B 170 ? THR B 168 . ? 1_555 ? 23 AC2 15 TYR B 218 ? TYR B 216 . ? 1_555 ? 24 AC2 15 ARG B 273 ? ARG B 271 . ? 1_555 ? 25 AC2 15 SER B 274 ? SER B 272 . ? 1_555 ? 26 AC2 15 GLU B 275 ? GLU B 273 . ? 1_555 ? 27 AC2 15 ASP B 297 ? ASP B 295 . ? 1_555 ? 28 AC2 15 GLY B 298 ? GLY B 296 . ? 1_555 ? 29 AC2 15 LYS B 379 ? LYS B 377 . ? 1_555 ? 30 AC3 3 PHE A 203 ? PHE A 201 . ? 1_555 ? 31 AC3 3 ASN A 205 ? ASN A 203 . ? 1_555 ? 32 AC3 3 HOH F . ? HOH A 738 . ? 1_555 ? # _atom_sites.entry_id 5CNJ _atom_sites.fract_transf_matrix[1][1] 0.012439 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.006448 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.010786 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ALA A 1 24 ? -7.501 14.544 -40.319 1.00 77.58 ? 22 ALA A N 1 ATOM 2 C CA . ALA A 1 24 ? -7.054 14.740 -38.938 1.00 77.51 ? 22 ALA A CA 1 ATOM 3 C C . ALA A 1 24 ? -5.543 15.040 -38.816 1.00 80.55 ? 22 ALA A C 1 ATOM 4 O O . ALA A 1 24 ? -4.750 14.670 -39.696 1.00 80.87 ? 22 ALA A O 1 ATOM 5 C CB . ALA A 1 24 ? -7.422 13.533 -38.079 1.00 78.17 ? 22 ALA A CB 1 ATOM 6 N N . LYS A 1 25 ? -5.162 15.711 -37.700 1.00 74.08 ? 23 LYS A N 1 ATOM 7 C CA . LYS A 1 25 ? -3.792 16.102 -37.359 1.00 71.70 ? 23 LYS A CA 1 ATOM 8 C C . LYS A 1 25 ? -3.113 15.031 -36.484 1.00 71.18 ? 23 LYS A C 1 ATOM 9 O O . LYS A 1 25 ? -3.751 14.450 -35.593 1.00 70.19 ? 23 LYS A O 1 ATOM 10 C CB . LYS A 1 25 ? -3.771 17.468 -36.639 1.00 73.61 ? 23 LYS A CB 1 ATOM 11 C CG . LYS A 1 25 ? -4.401 18.635 -37.402 1.00 75.22 ? 23 LYS A CG 1 ATOM 12 C CD . LYS A 1 25 ? -3.546 19.110 -38.562 1.00 74.44 ? 23 LYS A CD 1 ATOM 13 C CE . LYS A 1 25 ? -4.290 20.060 -39.461 1.00 72.31 ? 23 LYS A CE 1 ATOM 14 N NZ . LYS A 1 25 ? -3.696 20.072 -40.821 1.00 75.79 ? 23 LYS A NZ 1 ATOM 15 N N . LYS A 1 26 ? -1.824 14.812 -36.681 1.00 64.07 ? 24 LYS A N 1 ATOM 16 C CA . LYS A 1 26 ? -1.096 13.784 -35.960 1.00 61.50 ? 24 LYS A CA 1 ATOM 17 C C . LYS A 1 26 ? -0.627 14.215 -34.603 1.00 61.99 ? 24 LYS A C 1 ATOM 18 O O . LYS A 1 26 ? -0.603 15.370 -34.286 1.00 61.47 ? 24 LYS A O 1 ATOM 19 C CB . LYS A 1 26 ? 0.124 13.316 -36.735 1.00 61.96 ? 24 LYS A CB 1 ATOM 20 C CG . LYS A 1 26 ? 0.246 13.816 -38.144 1.00 63.60 ? 24 LYS A CG 1 ATOM 21 C CD . LYS A 1 26 ? 1.678 13.769 -38.589 1.00 62.16 ? 24 LYS A CD 1 ATOM 22 C CE . LYS A 1 26 ? 1.770 13.753 -40.088 1.00 61.09 ? 24 LYS A CE 1 ATOM 23 N NZ . LYS A 1 26 ? 2.797 14.717 -40.510 1.00 70.40 ? 24 LYS A NZ 1 ATOM 24 N N . VAL A 1 27 ? -0.217 13.248 -33.816 1.00 56.27 ? 25 VAL A N 1 ATOM 25 C CA . VAL A 1 27 ? 0.273 13.500 -32.496 1.00 55.32 ? 25 VAL A CA 1 ATOM 26 C C . VAL A 1 27 ? 1.497 12.635 -32.352 1.00 58.74 ? 25 VAL A C 1 ATOM 27 O O . VAL A 1 27 ? 1.633 11.663 -33.037 1.00 58.88 ? 25 VAL A O 1 ATOM 28 C CB . VAL A 1 27 ? -0.796 13.172 -31.433 1.00 58.24 ? 25 VAL A CB 1 ATOM 29 C CG1 . VAL A 1 27 ? -1.650 12.011 -31.853 1.00 57.81 ? 25 VAL A CG1 1 ATOM 30 C CG2 . VAL A 1 27 ? -0.194 12.912 -30.076 1.00 58.18 ? 25 VAL A CG2 1 ATOM 31 N N . LEU A 1 28 ? 2.378 12.996 -31.444 1.00 52.81 ? 26 LEU A N 1 ATOM 32 C CA . LEU A 1 28 ? 3.559 12.231 -31.170 1.00 51.65 ? 26 LEU A CA 1 ATOM 33 C C . LEU A 1 28 ? 3.393 11.566 -29.842 1.00 56.66 ? 26 LEU A C 1 ATOM 34 O O . LEU A 1 28 ? 3.343 12.237 -28.862 1.00 56.17 ? 26 LEU A O 1 ATOM 35 C CB . LEU A 1 28 ? 4.701 13.191 -31.054 1.00 51.28 ? 26 LEU A CB 1 ATOM 36 C CG . LEU A 1 28 ? 6.136 12.717 -31.091 1.00 54.62 ? 26 LEU A CG 1 ATOM 37 C CD1 . LEU A 1 28 ? 7.005 13.913 -31.362 1.00 53.96 ? 26 LEU A CD1 1 ATOM 38 C CD2 . LEU A 1 28 ? 6.549 12.049 -29.806 1.00 53.14 ? 26 LEU A CD2 1 ATOM 39 N N . THR A 1 29 ? 3.305 10.246 -29.795 1.00 53.79 ? 27 THR A N 1 ATOM 40 C CA . THR A 1 29 ? 3.119 9.566 -28.528 1.00 52.39 ? 27 THR A CA 1 ATOM 41 C C . THR A 1 29 ? 4.231 8.628 -28.220 1.00 54.88 ? 27 THR A C 1 ATOM 42 O O . THR A 1 29 ? 4.724 7.962 -29.084 1.00 55.89 ? 27 THR A O 1 ATOM 43 C CB . THR A 1 29 ? 1.840 8.737 -28.482 1.00 57.01 ? 27 THR A CB 1 ATOM 44 O OG1 . THR A 1 29 ? 1.965 7.665 -29.395 1.00 54.22 ? 27 THR A OG1 1 ATOM 45 C CG2 . THR A 1 29 ? 0.668 9.538 -28.855 1.00 58.27 ? 27 THR A CG2 1 ATOM 46 N N . LEU A 1 30 ? 4.587 8.585 -26.950 1.00 49.02 ? 28 LEU A N 1 ATOM 47 C CA . LEU A 1 30 ? 5.596 7.714 -26.398 1.00 47.50 ? 28 LEU A CA 1 ATOM 48 C C . LEU A 1 30 ? 5.042 7.099 -25.148 1.00 51.49 ? 28 LEU A C 1 ATOM 49 O O . LEU A 1 30 ? 4.406 7.771 -24.388 1.00 53.08 ? 28 LEU A O 1 ATOM 50 C CB . LEU A 1 30 ? 6.792 8.528 -26.006 1.00 46.82 ? 28 LEU A CB 1 ATOM 51 C CG . LEU A 1 30 ? 7.967 8.458 -26.938 1.00 50.11 ? 28 LEU A CG 1 ATOM 52 C CD1 . LEU A 1 30 ? 7.530 8.595 -28.367 1.00 48.47 ? 28 LEU A CD1 1 ATOM 53 C CD2 . LEU A 1 30 ? 8.901 9.562 -26.561 1.00 53.77 ? 28 LEU A CD2 1 ATOM 54 N N . GLU A 1 31 ? 5.298 5.823 -24.928 1.00 45.25 ? 29 GLU A N 1 ATOM 55 C CA . GLU A 1 31 ? 4.750 5.109 -23.800 1.00 43.58 ? 29 GLU A CA 1 ATOM 56 C C . GLU A 1 31 ? 5.588 5.195 -22.558 1.00 44.41 ? 29 GLU A C 1 ATOM 57 O O . GLU A 1 31 ? 6.778 5.266 -22.616 1.00 44.26 ? 29 GLU A O 1 ATOM 58 C CB . GLU A 1 31 ? 4.550 3.649 -24.163 1.00 45.43 ? 29 GLU A CB 1 ATOM 59 C CG . GLU A 1 31 ? 3.177 3.312 -24.703 1.00 66.04 ? 29 GLU A CG 1 ATOM 60 C CD . GLU A 1 31 ? 3.047 1.858 -25.123 1.00 107.39 ? 29 GLU A CD 1 ATOM 61 O OE1 . GLU A 1 31 ? 4.000 1.318 -25.714 1.00 115.94 ? 29 GLU A OE1 1 ATOM 62 O OE2 . GLU A 1 31 ? 1.988 1.245 -24.871 1.00 101.99 ? 29 GLU A OE2 1 ATOM 63 N N . GLY A 1 32 ? 4.929 5.170 -21.420 1.00 39.57 ? 30 GLY A N 1 ATOM 64 C CA . GLY A 1 32 ? 5.597 5.220 -20.148 1.00 39.14 ? 30 GLY A CA 1 ATOM 65 C C . GLY A 1 32 ? 4.628 4.984 -19.028 1.00 45.27 ? 30 GLY A C 1 ATOM 66 O O . GLY A 1 32 ? 3.470 4.764 -19.252 1.00 46.09 ? 30 GLY A O 1 ATOM 67 N N . ASP A 1 33 ? 5.113 5.024 -17.809 1.00 43.23 ? 31 ASP A N 1 ATOM 68 C CA . ASP A 1 33 ? 4.274 4.766 -16.671 1.00 43.99 ? 31 ASP A CA 1 ATOM 69 C C . ASP A 1 33 ? 3.500 6.010 -16.371 1.00 50.26 ? 31 ASP A C 1 ATOM 70 O O . ASP A 1 33 ? 2.320 5.986 -16.134 1.00 52.14 ? 31 ASP A O 1 ATOM 71 C CB . ASP A 1 33 ? 5.135 4.359 -15.492 1.00 46.22 ? 31 ASP A CB 1 ATOM 72 C CG . ASP A 1 33 ? 6.018 3.180 -15.800 1.00 56.83 ? 31 ASP A CG 1 ATOM 73 O OD1 . ASP A 1 33 ? 5.516 2.175 -16.281 1.00 58.40 ? 31 ASP A OD1 1 ATOM 74 O OD2 . ASP A 1 33 ? 7.220 3.238 -15.562 1.00 57.89 ? 31 ASP A OD2 1 ATOM 75 N N . LEU A 1 34 ? 4.207 7.114 -16.413 1.00 44.59 ? 32 LEU A N 1 ATOM 76 C CA . LEU A 1 34 ? 3.613 8.445 -16.299 1.00 41.67 ? 32 LEU A CA 1 ATOM 77 C C . LEU A 1 34 ? 3.822 9.118 -17.638 1.00 47.50 ? 32 LEU A C 1 ATOM 78 O O . LEU A 1 34 ? 4.910 8.996 -18.213 1.00 46.74 ? 32 LEU A O 1 ATOM 79 C CB . LEU A 1 34 ? 4.234 9.249 -15.139 1.00 39.92 ? 32 LEU A CB 1 ATOM 80 C CG . LEU A 1 34 ? 3.902 8.739 -13.716 1.00 41.68 ? 32 LEU A CG 1 ATOM 81 C CD1 . LEU A 1 34 ? 4.556 9.558 -12.667 1.00 40.17 ? 32 LEU A CD1 1 ATOM 82 C CD2 . LEU A 1 34 ? 2.438 8.740 -13.464 1.00 43.31 ? 32 LEU A CD2 1 ATOM 83 N N . VAL A 1 35 ? 2.756 9.760 -18.175 1.00 44.98 ? 33 VAL A N 1 ATOM 84 C CA . VAL A 1 35 ? 2.747 10.458 -19.469 1.00 43.75 ? 33 VAL A CA 1 ATOM 85 C C . VAL A 1 35 ? 2.610 11.997 -19.321 1.00 48.07 ? 33 VAL A C 1 ATOM 86 O O . VAL A 1 35 ? 1.675 12.513 -18.682 1.00 47.86 ? 33 VAL A O 1 ATOM 87 C CB . VAL A 1 35 ? 1.686 9.868 -20.425 1.00 47.49 ? 33 VAL A CB 1 ATOM 88 C CG1 . VAL A 1 35 ? 1.758 10.532 -21.810 1.00 47.58 ? 33 VAL A CG1 1 ATOM 89 C CG2 . VAL A 1 35 ? 1.837 8.353 -20.545 1.00 46.86 ? 33 VAL A CG2 1 ATOM 90 N N . LEU A 1 36 ? 3.565 12.709 -19.924 1.00 43.81 ? 34 LEU A N 1 ATOM 91 C CA . LEU A 1 36 ? 3.651 14.159 -19.916 1.00 42.08 ? 34 LEU A CA 1 ATOM 92 C C . LEU A 1 36 ? 3.175 14.706 -21.221 1.00 47.91 ? 34 LEU A C 1 ATOM 93 O O . LEU A 1 36 ? 3.561 14.233 -22.283 1.00 48.00 ? 34 LEU A O 1 ATOM 94 C CB . LEU A 1 36 ? 5.103 14.657 -19.639 1.00 40.79 ? 34 LEU A CB 1 ATOM 95 C CG . LEU A 1 36 ? 5.727 14.304 -18.261 1.00 42.56 ? 34 LEU A CG 1 ATOM 96 C CD1 . LEU A 1 36 ? 7.056 15.020 -18.055 1.00 40.14 ? 34 LEU A CD1 1 ATOM 97 C CD2 . LEU A 1 36 ? 4.765 14.584 -17.102 1.00 42.55 ? 34 LEU A CD2 1 ATOM 98 N N . GLY A 1 37 ? 2.353 15.729 -21.129 1.00 45.21 ? 35 GLY A N 1 ATOM 99 C CA . GLY A 1 37 ? 1.846 16.425 -22.293 1.00 44.25 ? 35 GLY A CA 1 ATOM 100 C C . GLY A 1 37 ? 2.860 17.402 -22.839 1.00 43.82 ? 35 GLY A C 1 ATOM 101 O O . GLY A 1 37 ? 3.651 17.962 -22.096 1.00 42.48 ? 35 GLY A O 1 ATOM 102 N N . GLY A 1 38 ? 2.818 17.605 -24.136 1.00 39.23 ? 36 GLY A N 1 ATOM 103 C CA . GLY A 1 38 ? 3.695 18.529 -24.819 1.00 38.47 ? 36 GLY A CA 1 ATOM 104 C C . GLY A 1 38 ? 2.894 19.380 -25.768 1.00 41.94 ? 36 GLY A C 1 ATOM 105 O O . GLY A 1 38 ? 1.941 18.888 -26.373 1.00 40.56 ? 36 GLY A O 1 ATOM 106 N N . LEU A 1 39 ? 3.279 20.666 -25.899 1.00 38.72 ? 37 LEU A N 1 ATOM 107 C CA . LEU A 1 39 ? 2.610 21.629 -26.765 1.00 37.70 ? 37 LEU A CA 1 ATOM 108 C C . LEU A 1 39 ? 3.643 22.542 -27.354 1.00 40.80 ? 37 LEU A C 1 ATOM 109 O O . LEU A 1 39 ? 4.337 23.248 -26.613 1.00 41.46 ? 37 LEU A O 1 ATOM 110 C CB . LEU A 1 39 ? 1.581 22.424 -25.966 1.00 38.04 ? 37 LEU A CB 1 ATOM 111 C CG . LEU A 1 39 ? 0.439 22.997 -26.784 1.00 43.86 ? 37 LEU A CG 1 ATOM 112 C CD1 . LEU A 1 39 ? -0.375 21.879 -27.476 1.00 44.11 ? 37 LEU A CD1 1 ATOM 113 C CD2 . LEU A 1 39 ? -0.445 23.904 -25.923 1.00 44.98 ? 37 LEU A CD2 1 ATOM 114 N N . PHE A 1 40 ? 3.811 22.464 -28.675 1.00 35.12 ? 38 PHE A N 1 ATOM 115 C CA . PHE A 1 40 ? 4.814 23.233 -29.385 1.00 35.59 ? 38 PHE A CA 1 ATOM 116 C C . PHE A 1 40 ? 4.233 23.800 -30.686 1.00 41.74 ? 38 PHE A C 1 ATOM 117 O O . PHE A 1 40 ? 3.331 23.175 -31.274 1.00 41.56 ? 38 PHE A O 1 ATOM 118 C CB . PHE A 1 40 ? 6.053 22.350 -29.690 1.00 37.11 ? 38 PHE A CB 1 ATOM 119 C CG . PHE A 1 40 ? 6.798 21.881 -28.470 1.00 37.56 ? 38 PHE A CG 1 ATOM 120 C CD1 . PHE A 1 40 ? 7.762 22.681 -27.876 1.00 37.90 ? 38 PHE A CD1 1 ATOM 121 C CD2 . PHE A 1 40 ? 6.523 20.639 -27.899 1.00 39.89 ? 38 PHE A CD2 1 ATOM 122 C CE1 . PHE A 1 40 ? 8.412 22.269 -26.712 1.00 38.07 ? 38 PHE A CE1 1 ATOM 123 C CE2 . PHE A 1 40 ? 7.170 20.227 -26.734 1.00 41.41 ? 38 PHE A CE2 1 ATOM 124 C CZ . PHE A 1 40 ? 8.113 21.050 -26.149 1.00 38.91 ? 38 PHE A CZ 1 ATOM 125 N N . PRO A 1 41 ? 4.737 24.973 -31.157 1.00 38.15 ? 39 PRO A N 1 ATOM 126 C CA . PRO A 1 41 ? 4.213 25.540 -32.408 1.00 38.32 ? 39 PRO A CA 1 ATOM 127 C C . PRO A 1 41 ? 4.951 24.896 -33.582 1.00 44.21 ? 39 PRO A C 1 ATOM 128 O O . PRO A 1 41 ? 5.847 25.512 -34.180 1.00 45.32 ? 39 PRO A O 1 ATOM 129 C CB . PRO A 1 41 ? 4.478 27.046 -32.257 1.00 39.13 ? 39 PRO A CB 1 ATOM 130 C CG . PRO A 1 41 ? 5.663 27.131 -31.366 1.00 43.85 ? 39 PRO A CG 1 ATOM 131 C CD . PRO A 1 41 ? 5.791 25.831 -30.584 1.00 39.81 ? 39 PRO A CD 1 ATOM 132 N N . VAL A 1 42 ? 4.607 23.621 -33.868 1.00 38.01 ? 40 VAL A N 1 ATOM 133 C CA . VAL A 1 42 ? 5.284 22.843 -34.892 1.00 37.33 ? 40 VAL A CA 1 ATOM 134 C C . VAL A 1 42 ? 5.153 23.560 -36.219 1.00 43.65 ? 40 VAL A C 1 ATOM 135 O O . VAL A 1 42 ? 6.164 23.766 -36.899 1.00 43.19 ? 40 VAL A O 1 ATOM 136 C CB . VAL A 1 42 ? 4.866 21.347 -34.935 1.00 40.25 ? 40 VAL A CB 1 ATOM 137 C CG1 . VAL A 1 42 ? 5.685 20.575 -35.969 1.00 39.54 ? 40 VAL A CG1 1 ATOM 138 C CG2 . VAL A 1 42 ? 4.967 20.697 -33.551 1.00 39.71 ? 40 VAL A CG2 1 ATOM 139 N N . HIS A 1 43 ? 3.927 24.014 -36.539 1.00 41.37 ? 41 HIS A N 1 ATOM 140 C CA . HIS A 1 43 ? 3.669 24.789 -37.755 1.00 41.54 ? 41 HIS A CA 1 ATOM 141 C C . HIS A 1 43 ? 3.383 26.242 -37.398 1.00 47.67 ? 41 HIS A C 1 ATOM 142 O O . HIS A 1 43 ? 3.222 26.572 -36.217 1.00 47.88 ? 41 HIS A O 1 ATOM 143 C CB . HIS A 1 43 ? 2.504 24.189 -38.553 1.00 41.23 ? 41 HIS A CB 1 ATOM 144 C CG . HIS A 1 43 ? 2.805 22.819 -39.054 1.00 43.33 ? 41 HIS A CG 1 ATOM 145 N ND1 . HIS A 1 43 ? 2.551 21.711 -38.281 1.00 44.13 ? 41 HIS A ND1 1 ATOM 146 C CD2 . HIS A 1 43 ? 3.396 22.428 -40.207 1.00 44.18 ? 41 HIS A CD2 1 ATOM 147 C CE1 . HIS A 1 43 ? 2.969 20.678 -38.987 1.00 43.33 ? 41 HIS A CE1 1 ATOM 148 N NE2 . HIS A 1 43 ? 3.477 21.060 -40.161 1.00 43.63 ? 41 HIS A NE2 1 ATOM 149 N N . GLN A 1 44 ? 3.334 27.108 -38.420 1.00 44.79 ? 42 GLN A N 1 ATOM 150 C CA . GLN A 1 44 ? 3.009 28.530 -38.274 1.00 44.14 ? 42 GLN A CA 1 ATOM 151 C C . GLN A 1 44 ? 1.500 28.623 -38.438 1.00 50.04 ? 42 GLN A C 1 ATOM 152 O O . GLN A 1 44 ? 0.856 27.619 -38.767 1.00 48.58 ? 42 GLN A O 1 ATOM 153 C CB . GLN A 1 44 ? 3.667 29.352 -39.390 1.00 44.95 ? 42 GLN A CB 1 ATOM 154 C CG . GLN A 1 44 ? 5.157 29.115 -39.591 1.00 58.28 ? 42 GLN A CG 1 ATOM 155 C CD . GLN A 1 44 ? 5.696 29.879 -40.769 1.00 73.18 ? 42 GLN A CD 1 ATOM 156 O OE1 . GLN A 1 44 ? 4.954 30.315 -41.663 1.00 73.60 ? 42 GLN A OE1 1 ATOM 157 N NE2 . GLN A 1 44 ? 7.007 30.069 -40.785 1.00 56.85 ? 42 GLN A NE2 1 ATOM 158 N N . LYS A 1 45 ? 0.936 29.822 -38.234 1.00 49.98 ? 43 LYS A N 1 ATOM 159 C CA . LYS A 1 45 ? -0.483 30.074 -38.434 1.00 51.70 ? 43 LYS A CA 1 ATOM 160 C C . LYS A 1 45 ? -0.716 29.814 -39.922 1.00 60.61 ? 43 LYS A C 1 ATOM 161 O O . LYS A 1 45 ? 0.096 30.224 -40.759 1.00 60.00 ? 43 LYS A O 1 ATOM 162 C CB . LYS A 1 45 ? -0.786 31.559 -38.161 1.00 54.43 ? 43 LYS A CB 1 ATOM 163 C CG . LYS A 1 45 ? -1.256 31.918 -36.765 1.00 71.31 ? 43 LYS A CG 1 ATOM 164 C CD . LYS A 1 45 ? -1.241 33.453 -36.546 1.00 91.71 ? 43 LYS A CD 1 ATOM 165 C CE . LYS A 1 45 ? -2.415 34.204 -37.173 1.00 112.07 ? 43 LYS A CE 1 ATOM 166 N NZ . LYS A 1 45 ? -2.381 35.670 -36.894 1.00 120.44 ? 43 LYS A NZ 1 ATOM 167 N N . GLY A 1 46 ? -1.791 29.126 -40.249 1.00 61.70 ? 44 GLY A N 1 ATOM 168 C CA . GLY A 1 46 ? -2.112 28.888 -41.650 1.00 63.57 ? 44 GLY A CA 1 ATOM 169 C C . GLY A 1 46 ? -2.638 30.158 -42.289 1.00 72.51 ? 44 GLY A C 1 ATOM 170 O O . GLY A 1 46 ? -2.646 31.223 -41.654 1.00 71.79 ? 44 GLY A O 1 ATOM 171 N N . GLY A 1 47 ? -3.099 30.047 -43.531 1.00 72.61 ? 45 GLY A N 1 ATOM 172 C CA . GLY A 1 47 ? -3.655 31.187 -44.246 1.00 73.79 ? 45 GLY A CA 1 ATOM 173 C C . GLY A 1 47 ? -4.941 31.720 -43.627 1.00 80.42 ? 45 GLY A C 1 ATOM 174 O O . GLY A 1 47 ? -5.379 31.230 -42.574 1.00 79.34 ? 45 GLY A O 1 ATOM 175 N N . PRO A 1 48 ? -5.608 32.717 -44.266 1.00 78.92 ? 46 PRO A N 1 ATOM 176 C CA . PRO A 1 48 ? -6.872 33.225 -43.693 1.00 78.73 ? 46 PRO A CA 1 ATOM 177 C C . PRO A 1 48 ? -8.008 32.189 -43.687 1.00 81.87 ? 46 PRO A C 1 ATOM 178 O O . PRO A 1 48 ? -9.021 32.423 -43.029 1.00 81.77 ? 46 PRO A O 1 ATOM 179 C CB . PRO A 1 48 ? -7.204 34.448 -44.560 1.00 80.45 ? 46 PRO A CB 1 ATOM 180 C CG . PRO A 1 48 ? -5.964 34.725 -45.365 1.00 85.16 ? 46 PRO A CG 1 ATOM 181 C CD . PRO A 1 48 ? -5.275 33.410 -45.527 1.00 80.58 ? 46 PRO A CD 1 ATOM 182 N N . ALA A 1 49 ? -7.813 31.028 -44.373 1.00 77.09 ? 47 ALA A N 1 ATOM 183 C CA . ALA A 1 49 ? -8.786 29.939 -44.486 1.00 76.63 ? 47 ALA A CA 1 ATOM 184 C C . ALA A 1 49 ? -8.218 28.506 -44.209 1.00 79.65 ? 47 ALA A C 1 ATOM 185 O O . ALA A 1 49 ? -8.959 27.526 -44.343 1.00 79.55 ? 47 ALA A O 1 ATOM 186 C CB . ALA A 1 49 ? -9.463 29.998 -45.843 1.00 77.39 ? 47 ALA A CB 1 ATOM 187 N N . GLU A 1 50 ? -6.927 28.394 -43.803 1.00 74.49 ? 48 GLU A N 1 ATOM 188 C CA . GLU A 1 50 ? -6.267 27.129 -43.425 1.00 72.97 ? 48 GLU A CA 1 ATOM 189 C C . GLU A 1 50 ? -5.770 27.250 -41.991 1.00 72.51 ? 48 GLU A C 1 ATOM 190 O O . GLU A 1 50 ? -5.288 28.316 -41.623 1.00 73.67 ? 48 GLU A O 1 ATOM 191 C CB . GLU A 1 50 ? -5.087 26.793 -44.354 1.00 74.66 ? 48 GLU A CB 1 ATOM 192 C CG . GLU A 1 50 ? -5.326 25.586 -45.257 1.00 90.64 ? 48 GLU A CG 1 ATOM 193 C CD . GLU A 1 50 ? -5.692 24.237 -44.647 1.00 118.54 ? 48 GLU A CD 1 ATOM 194 O OE1 . GLU A 1 50 ? -5.520 24.045 -43.420 1.00 113.66 ? 48 GLU A OE1 1 ATOM 195 O OE2 . GLU A 1 50 ? -6.142 23.358 -45.417 1.00 115.41 ? 48 GLU A OE2 1 ATOM 196 N N . ASP A 1 51 ? -5.865 26.194 -41.178 1.00 64.65 ? 49 ASP A N 1 ATOM 197 C CA . ASP A 1 51 ? -5.436 26.323 -39.779 1.00 62.95 ? 49 ASP A CA 1 ATOM 198 C C . ASP A 1 51 ? -3.910 26.273 -39.561 1.00 61.79 ? 49 ASP A C 1 ATOM 199 O O . ASP A 1 51 ? -3.368 27.072 -38.786 1.00 61.52 ? 49 ASP A O 1 ATOM 200 C CB . ASP A 1 51 ? -6.148 25.307 -38.865 1.00 65.20 ? 49 ASP A CB 1 ATOM 201 C CG . ASP A 1 51 ? -7.627 25.617 -38.647 1.00 73.83 ? 49 ASP A CG 1 ATOM 202 O OD1 . ASP A 1 51 ? -8.049 26.757 -38.957 1.00 74.82 ? 49 ASP A OD1 1 ATOM 203 O OD2 . ASP A 1 51 ? -8.363 24.720 -38.160 1.00 76.27 ? 49 ASP A OD2 1 ATOM 204 N N . CYS A 1 52 ? -3.224 25.344 -40.232 1.00 53.75 ? 50 CYS A N 1 ATOM 205 C CA . CYS A 1 52 ? -1.792 25.191 -40.072 1.00 51.36 ? 50 CYS A CA 1 ATOM 206 C C . CYS A 1 52 ? -1.013 25.573 -41.316 1.00 54.68 ? 50 CYS A C 1 ATOM 207 O O . CYS A 1 52 ? -1.488 25.383 -42.440 1.00 56.72 ? 50 CYS A O 1 ATOM 208 C CB . CYS A 1 52 ? -1.461 23.788 -39.576 1.00 50.61 ? 50 CYS A CB 1 ATOM 209 S SG . CYS A 1 52 ? -2.339 23.345 -38.046 1.00 53.60 ? 50 CYS A SG 1 ATOM 210 N N . GLY A 1 53 ? 0.130 26.207 -41.092 1.00 48.20 ? 51 GLY A N 1 ATOM 211 C CA . GLY A 1 53 ? 0.993 26.708 -42.152 1.00 46.85 ? 51 GLY A CA 1 ATOM 212 C C . GLY A 1 53 ? 2.264 25.909 -42.302 1.00 48.30 ? 51 GLY A C 1 ATOM 213 O O . GLY A 1 53 ? 2.308 24.755 -41.874 1.00 47.46 ? 51 GLY A O 1 ATOM 214 N N . PRO A 1 54 ? 3.329 26.476 -42.907 1.00 44.63 ? 52 PRO A N 1 ATOM 215 C CA . PRO A 1 54 ? 4.582 25.701 -43.031 1.00 43.77 ? 52 PRO A CA 1 ATOM 216 C C . PRO A 1 54 ? 5.217 25.383 -41.677 1.00 48.17 ? 52 PRO A C 1 ATOM 217 O O . PRO A 1 54 ? 4.752 25.858 -40.638 1.00 48.20 ? 52 PRO A O 1 ATOM 218 C CB . PRO A 1 54 ? 5.467 26.546 -43.945 1.00 45.22 ? 52 PRO A CB 1 ATOM 219 C CG . PRO A 1 54 ? 4.879 27.912 -43.940 1.00 49.96 ? 52 PRO A CG 1 ATOM 220 C CD . PRO A 1 54 ? 3.454 27.839 -43.476 1.00 46.02 ? 52 PRO A CD 1 ATOM 221 N N . VAL A 1 55 ? 6.227 24.516 -41.686 1.00 44.79 ? 53 VAL A N 1 ATOM 222 C CA . VAL A 1 55 ? 6.919 24.021 -40.492 1.00 43.88 ? 53 VAL A CA 1 ATOM 223 C C . VAL A 1 55 ? 7.799 25.126 -39.894 1.00 50.03 ? 53 VAL A C 1 ATOM 224 O O . VAL A 1 55 ? 8.347 25.940 -40.633 1.00 48.45 ? 53 VAL A O 1 ATOM 225 C CB . VAL A 1 55 ? 7.719 22.725 -40.804 1.00 45.81 ? 53 VAL A CB 1 ATOM 226 C CG1 . VAL A 1 55 ? 8.291 22.094 -39.551 1.00 45.40 ? 53 VAL A CG1 1 ATOM 227 C CG2 . VAL A 1 55 ? 6.872 21.718 -41.554 1.00 45.13 ? 53 VAL A CG2 1 ATOM 228 N N . ASN A 1 56 ? 7.855 25.180 -38.547 1.00 50.80 ? 54 ASN A N 1 ATOM 229 C CA . ASN A 1 56 ? 8.667 26.097 -37.740 1.00 52.21 ? 54 ASN A CA 1 ATOM 230 C C . ASN A 1 56 ? 9.848 25.269 -37.271 1.00 56.56 ? 54 ASN A C 1 ATOM 231 O O . ASN A 1 56 ? 9.694 24.459 -36.361 1.00 56.12 ? 54 ASN A O 1 ATOM 232 C CB . ASN A 1 56 ? 7.906 26.581 -36.505 1.00 55.90 ? 54 ASN A CB 1 ATOM 233 C CG . ASN A 1 56 ? 7.338 27.958 -36.566 1.00 77.07 ? 54 ASN A CG 1 ATOM 234 O OD1 . ASN A 1 56 ? 8.029 28.947 -36.842 1.00 77.80 ? 54 ASN A OD1 1 ATOM 235 N ND2 . ASN A 1 56 ? 6.091 28.053 -36.157 1.00 65.15 ? 54 ASN A ND2 1 ATOM 236 N N . GLU A 1 57 ? 11.003 25.445 -37.926 1.00 52.58 ? 55 GLU A N 1 ATOM 237 C CA . GLU A 1 57 ? 12.239 24.739 -37.645 1.00 51.81 ? 55 GLU A CA 1 ATOM 238 C C . GLU A 1 57 ? 12.752 24.925 -36.213 1.00 53.47 ? 55 GLU A C 1 ATOM 239 O O . GLU A 1 57 ? 13.022 23.931 -35.536 1.00 53.45 ? 55 GLU A O 1 ATOM 240 C CB . GLU A 1 57 ? 13.309 25.124 -38.689 1.00 53.41 ? 55 GLU A CB 1 ATOM 241 C CG . GLU A 1 57 ? 14.736 24.847 -38.244 1.00 63.15 ? 55 GLU A CG 1 ATOM 242 C CD . GLU A 1 57 ? 15.801 24.850 -39.313 1.00 77.94 ? 55 GLU A CD 1 ATOM 243 O OE1 . GLU A 1 57 ? 15.753 25.710 -40.224 1.00 69.37 ? 55 GLU A OE1 1 ATOM 244 O OE2 . GLU A 1 57 ? 16.722 24.011 -39.201 1.00 73.23 ? 55 GLU A OE2 1 ATOM 245 N N . HIS A 1 58 ? 12.874 26.177 -35.751 1.00 48.95 ? 56 HIS A N 1 ATOM 246 C CA . HIS A 1 58 ? 13.459 26.484 -34.439 1.00 48.27 ? 56 HIS A CA 1 ATOM 247 C C . HIS A 1 58 ? 12.475 26.472 -33.277 1.00 50.65 ? 56 HIS A C 1 ATOM 248 O O . HIS A 1 58 ? 12.712 25.716 -32.330 1.00 51.02 ? 56 HIS A O 1 ATOM 249 C CB . HIS A 1 58 ? 14.241 27.797 -34.499 1.00 49.09 ? 56 HIS A CB 1 ATOM 250 C CG . HIS A 1 58 ? 15.187 27.795 -35.654 1.00 52.94 ? 56 HIS A CG 1 ATOM 251 N ND1 . HIS A 1 58 ? 14.858 28.413 -36.853 1.00 55.11 ? 56 HIS A ND1 1 ATOM 252 C CD2 . HIS A 1 58 ? 16.339 27.101 -35.821 1.00 54.78 ? 56 HIS A CD2 1 ATOM 253 C CE1 . HIS A 1 58 ? 15.849 28.131 -37.682 1.00 54.73 ? 56 HIS A CE1 1 ATOM 254 N NE2 . HIS A 1 58 ? 16.767 27.347 -37.099 1.00 54.97 ? 56 HIS A NE2 1 ATOM 255 N N . ARG A 1 59 ? 11.385 27.275 -33.327 1.00 44.85 ? 57 ARG A N 1 ATOM 256 C CA . ARG A 1 59 ? 10.423 27.299 -32.229 1.00 43.40 ? 57 ARG A CA 1 ATOM 257 C C . ARG A 1 59 ? 9.565 26.030 -32.173 1.00 46.68 ? 57 ARG A C 1 ATOM 258 O O . ARG A 1 59 ? 9.051 25.708 -31.101 1.00 46.06 ? 57 ARG A O 1 ATOM 259 C CB . ARG A 1 59 ? 9.559 28.571 -32.208 1.00 41.92 ? 57 ARG A CB 1 ATOM 260 C CG . ARG A 1 59 ? 10.316 29.884 -31.917 1.00 47.57 ? 57 ARG A CG 1 ATOM 261 C CD . ARG A 1 59 ? 9.404 31.126 -32.029 1.00 62.33 ? 57 ARG A CD 1 ATOM 262 N NE . ARG A 1 59 ? 8.538 31.088 -33.220 1.00 80.63 ? 57 ARG A NE 1 ATOM 263 C CZ . ARG A 1 59 ? 8.696 31.839 -34.313 1.00 101.66 ? 57 ARG A CZ 1 ATOM 264 N NH1 . ARG A 1 59 ? 7.879 31.693 -35.348 1.00 84.37 ? 57 ARG A NH1 1 ATOM 265 N NH2 . ARG A 1 59 ? 9.664 32.749 -34.373 1.00 92.66 ? 57 ARG A NH2 1 ATOM 266 N N . GLY A 1 60 ? 9.484 25.287 -33.277 1.00 43.17 ? 58 GLY A N 1 ATOM 267 C CA . GLY A 1 60 ? 8.703 24.048 -33.331 1.00 43.59 ? 58 GLY A CA 1 ATOM 268 C C . GLY A 1 60 ? 9.469 22.742 -33.155 1.00 47.93 ? 58 GLY A C 1 ATOM 269 O O . GLY A 1 60 ? 9.399 22.120 -32.091 1.00 46.92 ? 58 GLY A O 1 ATOM 270 N N . ILE A 1 61 ? 10.162 22.299 -34.231 1.00 45.70 ? 59 ILE A N 1 ATOM 271 C CA . ILE A 1 61 ? 10.956 21.067 -34.373 1.00 45.88 ? 59 ILE A CA 1 ATOM 272 C C . ILE A 1 61 ? 12.081 21.008 -33.373 1.00 50.81 ? 59 ILE A C 1 ATOM 273 O O . ILE A 1 61 ? 12.249 19.982 -32.719 1.00 50.90 ? 59 ILE A O 1 ATOM 274 C CB . ILE A 1 61 ? 11.475 20.910 -35.851 1.00 49.27 ? 59 ILE A CB 1 ATOM 275 C CG1 . ILE A 1 61 ? 10.312 20.763 -36.868 1.00 48.87 ? 59 ILE A CG1 1 ATOM 276 C CG2 . ILE A 1 61 ? 12.523 19.779 -36.024 1.00 49.75 ? 59 ILE A CG2 1 ATOM 277 C CD1 . ILE A 1 61 ? 9.286 19.616 -36.594 1.00 48.57 ? 59 ILE A CD1 1 ATOM 278 N N . GLN A 1 62 ? 12.857 22.091 -33.250 1.00 47.72 ? 60 GLN A N 1 ATOM 279 C CA . GLN A 1 62 ? 13.977 22.097 -32.320 1.00 48.05 ? 60 GLN A CA 1 ATOM 280 C C . GLN A 1 62 ? 13.500 22.058 -30.888 1.00 51.68 ? 60 GLN A C 1 ATOM 281 O O . GLN A 1 62 ? 14.001 21.236 -30.118 1.00 52.59 ? 60 GLN A O 1 ATOM 282 C CB . GLN A 1 62 ? 14.917 23.280 -32.576 1.00 49.79 ? 60 GLN A CB 1 ATOM 283 C CG . GLN A 1 62 ? 16.379 22.940 -32.415 1.00 50.22 ? 60 GLN A CG 1 ATOM 284 C CD . GLN A 1 62 ? 17.223 24.181 -32.433 1.00 62.10 ? 60 GLN A CD 1 ATOM 285 O OE1 . GLN A 1 62 ? 17.652 24.686 -31.401 1.00 58.26 ? 60 GLN A OE1 1 ATOM 286 N NE2 . GLN A 1 62 ? 17.533 24.663 -33.607 1.00 55.44 ? 60 GLN A NE2 1 ATOM 287 N N . ARG A 1 63 ? 12.496 22.895 -30.530 1.00 46.37 ? 61 ARG A N 1 ATOM 288 C CA . ARG A 1 63 ? 11.939 22.882 -29.165 1.00 44.79 ? 61 ARG A CA 1 ATOM 289 C C . ARG A 1 63 ? 11.257 21.538 -28.856 1.00 46.98 ? 61 ARG A C 1 ATOM 290 O O . ARG A 1 63 ? 11.388 21.027 -27.749 1.00 46.24 ? 61 ARG A O 1 ATOM 291 C CB . ARG A 1 63 ? 10.956 24.030 -28.950 1.00 41.42 ? 61 ARG A CB 1 ATOM 292 C CG . ARG A 1 63 ? 11.588 25.378 -28.805 1.00 41.95 ? 61 ARG A CG 1 ATOM 293 C CD . ARG A 1 63 ? 10.585 26.414 -28.353 1.00 39.65 ? 61 ARG A CD 1 ATOM 294 N NE . ARG A 1 63 ? 11.221 27.724 -28.356 1.00 37.22 ? 61 ARG A NE 1 ATOM 295 C CZ . ARG A 1 63 ? 10.592 28.881 -28.188 1.00 46.76 ? 61 ARG A CZ 1 ATOM 296 N NH1 . ARG A 1 63 ? 9.282 28.908 -27.983 1.00 31.98 ? 61 ARG A NH1 1 ATOM 297 N NH2 . ARG A 1 63 ? 11.268 30.021 -28.225 1.00 30.61 ? 61 ARG A NH2 1 ATOM 298 N N . LEU A 1 64 ? 10.550 20.968 -29.831 1.00 44.04 ? 62 LEU A N 1 ATOM 299 C CA . LEU A 1 64 ? 9.895 19.672 -29.672 1.00 45.48 ? 62 LEU A CA 1 ATOM 300 C C . LEU A 1 64 ? 10.941 18.582 -29.409 1.00 50.01 ? 62 LEU A C 1 ATOM 301 O O . LEU A 1 64 ? 10.780 17.792 -28.481 1.00 50.42 ? 62 LEU A O 1 ATOM 302 C CB . LEU A 1 64 ? 9.044 19.353 -30.918 1.00 46.02 ? 62 LEU A CB 1 ATOM 303 C CG . LEU A 1 64 ? 8.813 17.886 -31.279 1.00 51.89 ? 62 LEU A CG 1 ATOM 304 C CD1 . LEU A 1 64 ? 7.801 17.287 -30.380 1.00 52.88 ? 62 LEU A CD1 1 ATOM 305 C CD2 . LEU A 1 64 ? 8.314 17.761 -32.695 1.00 54.88 ? 62 LEU A CD2 1 ATOM 306 N N . GLU A 1 65 ? 12.024 18.579 -30.199 1.00 45.75 ? 63 GLU A N 1 ATOM 307 C CA . GLU A 1 65 ? 13.118 17.609 -30.085 1.00 44.69 ? 63 GLU A CA 1 ATOM 308 C C . GLU A 1 65 ? 13.850 17.740 -28.766 1.00 44.03 ? 63 GLU A C 1 ATOM 309 O O . GLU A 1 65 ? 14.237 16.728 -28.179 1.00 44.18 ? 63 GLU A O 1 ATOM 310 C CB . GLU A 1 65 ? 14.078 17.702 -31.293 1.00 45.94 ? 63 GLU A CB 1 ATOM 311 C CG . GLU A 1 65 ? 13.475 17.197 -32.609 1.00 45.54 ? 63 GLU A CG 1 ATOM 312 C CD . GLU A 1 65 ? 13.306 15.693 -32.691 1.00 55.68 ? 63 GLU A CD 1 ATOM 313 O OE1 . GLU A 1 65 ? 13.896 14.984 -31.846 1.00 36.88 ? 63 GLU A OE1 1 ATOM 314 O OE2 . GLU A 1 65 ? 12.579 15.223 -33.592 1.00 48.31 ? 63 GLU A OE2 1 ATOM 315 N N . ALA A 1 66 ? 13.959 18.967 -28.266 1.00 37.51 ? 64 ALA A N 1 ATOM 316 C CA . ALA A 1 66 ? 14.558 19.265 -26.978 1.00 37.69 ? 64 ALA A CA 1 ATOM 317 C C . ALA A 1 66 ? 13.784 18.615 -25.828 1.00 43.65 ? 64 ALA A C 1 ATOM 318 O O . ALA A 1 66 ? 14.428 18.200 -24.874 1.00 46.16 ? 64 ALA A O 1 ATOM 319 C CB . ALA A 1 66 ? 14.630 20.759 -26.781 1.00 38.54 ? 64 ALA A CB 1 ATOM 320 N N . MET A 1 67 ? 12.425 18.495 -25.917 1.00 37.67 ? 65 MET A N 1 ATOM 321 C CA . MET A 1 67 ? 11.630 17.826 -24.885 1.00 37.48 ? 65 MET A CA 1 ATOM 322 C C . MET A 1 67 ? 11.909 16.307 -24.940 1.00 43.87 ? 65 MET A C 1 ATOM 323 O O . MET A 1 67 ? 12.023 15.666 -23.881 1.00 45.03 ? 65 MET A O 1 ATOM 324 C CB . MET A 1 67 ? 10.111 18.116 -25.040 1.00 38.81 ? 65 MET A CB 1 ATOM 325 C CG . MET A 1 67 ? 9.226 17.263 -24.142 1.00 40.20 ? 65 MET A CG 1 ATOM 326 S SD . MET A 1 67 ? 7.505 17.796 -23.998 1.00 42.57 ? 65 MET A SD 1 ATOM 327 C CE . MET A 1 67 ? 6.819 16.390 -23.074 1.00 37.87 ? 65 MET A CE 1 ATOM 328 N N . LEU A 1 68 ? 12.010 15.753 -26.173 1.00 39.20 ? 66 LEU A N 1 ATOM 329 C CA . LEU A 1 68 ? 12.308 14.343 -26.454 1.00 39.90 ? 66 LEU A CA 1 ATOM 330 C C . LEU A 1 68 ? 13.708 13.972 -25.973 1.00 46.10 ? 66 LEU A C 1 ATOM 331 O O . LEU A 1 68 ? 13.905 12.877 -25.448 1.00 43.78 ? 66 LEU A O 1 ATOM 332 C CB . LEU A 1 68 ? 12.156 14.027 -27.956 1.00 39.87 ? 66 LEU A CB 1 ATOM 333 C CG . LEU A 1 68 ? 10.734 14.172 -28.543 1.00 43.68 ? 66 LEU A CG 1 ATOM 334 C CD1 . LEU A 1 68 ? 10.721 13.841 -30.031 1.00 43.64 ? 66 LEU A CD1 1 ATOM 335 C CD2 . LEU A 1 68 ? 9.776 13.297 -27.838 1.00 45.10 ? 66 LEU A CD2 1 ATOM 336 N N . PHE A 1 69 ? 14.668 14.897 -26.142 1.00 45.44 ? 67 PHE A N 1 ATOM 337 C CA . PHE A 1 69 ? 16.037 14.743 -25.674 1.00 46.56 ? 67 PHE A CA 1 ATOM 338 C C . PHE A 1 69 ? 16.037 14.638 -24.151 1.00 50.55 ? 67 PHE A C 1 ATOM 339 O O . PHE A 1 69 ? 16.661 13.734 -23.595 1.00 51.47 ? 67 PHE A O 1 ATOM 340 C CB . PHE A 1 69 ? 16.898 15.924 -26.161 1.00 48.86 ? 67 PHE A CB 1 ATOM 341 C CG . PHE A 1 69 ? 18.132 16.240 -25.343 1.00 50.64 ? 67 PHE A CG 1 ATOM 342 C CD1 . PHE A 1 69 ? 19.348 15.642 -25.634 1.00 53.64 ? 67 PHE A CD1 1 ATOM 343 C CD2 . PHE A 1 69 ? 18.090 17.189 -24.327 1.00 53.30 ? 67 PHE A CD2 1 ATOM 344 C CE1 . PHE A 1 69 ? 20.497 15.973 -24.909 1.00 55.06 ? 67 PHE A CE1 1 ATOM 345 C CE2 . PHE A 1 69 ? 19.234 17.507 -23.594 1.00 56.01 ? 67 PHE A CE2 1 ATOM 346 C CZ . PHE A 1 69 ? 20.428 16.890 -23.882 1.00 54.41 ? 67 PHE A CZ 1 ATOM 347 N N . ALA A 1 70 ? 15.317 15.545 -23.479 1.00 46.94 ? 68 ALA A N 1 ATOM 348 C CA . ALA A 1 70 ? 15.205 15.537 -22.013 1.00 46.29 ? 68 ALA A CA 1 ATOM 349 C C . ALA A 1 70 ? 14.582 14.215 -21.502 1.00 50.00 ? 68 ALA A C 1 ATOM 350 O O . ALA A 1 70 ? 15.160 13.581 -20.622 1.00 51.21 ? 68 ALA A O 1 ATOM 351 C CB . ALA A 1 70 ? 14.412 16.738 -21.538 1.00 46.33 ? 68 ALA A CB 1 ATOM 352 N N . LEU A 1 71 ? 13.471 13.767 -22.116 1.00 43.69 ? 69 LEU A N 1 ATOM 353 C CA . LEU A 1 71 ? 12.811 12.522 -21.749 1.00 42.49 ? 69 LEU A CA 1 ATOM 354 C C . LEU A 1 71 ? 13.772 11.311 -21.796 1.00 46.72 ? 69 LEU A C 1 ATOM 355 O O . LEU A 1 71 ? 13.905 10.604 -20.791 1.00 46.23 ? 69 LEU A O 1 ATOM 356 C CB . LEU A 1 71 ? 11.553 12.283 -22.609 1.00 41.65 ? 69 LEU A CB 1 ATOM 357 C CG . LEU A 1 71 ? 10.315 13.162 -22.329 1.00 44.49 ? 69 LEU A CG 1 ATOM 358 C CD1 . LEU A 1 71 ? 9.232 12.988 -23.435 1.00 44.24 ? 69 LEU A CD1 1 ATOM 359 C CD2 . LEU A 1 71 ? 9.738 12.932 -20.929 1.00 41.05 ? 69 LEU A CD2 1 ATOM 360 N N . ASP A 1 72 ? 14.475 11.126 -22.932 1.00 43.09 ? 70 ASP A N 1 ATOM 361 C CA . ASP A 1 72 ? 15.459 10.067 -23.187 1.00 42.68 ? 70 ASP A CA 1 ATOM 362 C C . ASP A 1 72 ? 16.512 10.037 -22.056 1.00 52.19 ? 70 ASP A C 1 ATOM 363 O O . ASP A 1 72 ? 16.688 9.008 -21.384 1.00 53.50 ? 70 ASP A O 1 ATOM 364 C CB . ASP A 1 72 ? 16.151 10.304 -24.538 1.00 42.47 ? 70 ASP A CB 1 ATOM 365 C CG . ASP A 1 72 ? 15.356 9.988 -25.785 1.00 48.29 ? 70 ASP A CG 1 ATOM 366 O OD1 . ASP A 1 72 ? 14.144 9.713 -25.669 1.00 47.99 ? 70 ASP A OD1 1 ATOM 367 O OD2 . ASP A 1 72 ? 15.945 10.033 -26.888 1.00 58.38 ? 70 ASP A OD2 1 ATOM 368 N N . ARG A 1 73 ? 17.151 11.190 -21.817 1.00 49.14 ? 71 ARG A N 1 ATOM 369 C CA . ARG A 1 73 ? 18.154 11.383 -20.784 1.00 49.53 ? 71 ARG A CA 1 ATOM 370 C C . ARG A 1 73 ? 17.641 11.034 -19.372 1.00 55.76 ? 71 ARG A C 1 ATOM 371 O O . ARG A 1 73 ? 18.359 10.383 -18.613 1.00 56.04 ? 71 ARG A O 1 ATOM 372 C CB . ARG A 1 73 ? 18.672 12.822 -20.850 1.00 49.50 ? 71 ARG A CB 1 ATOM 373 C CG . ARG A 1 73 ? 19.622 13.040 -22.011 1.00 65.93 ? 71 ARG A CG 1 ATOM 374 C CD . ARG A 1 73 ? 21.043 12.981 -21.506 1.00 87.90 ? 71 ARG A CD 1 ATOM 375 N NE . ARG A 1 73 ? 21.983 12.443 -22.482 1.00 102.28 ? 71 ARG A NE 1 ATOM 376 C CZ . ARG A 1 73 ? 23.300 12.585 -22.389 1.00 120.49 ? 71 ARG A CZ 1 ATOM 377 N NH1 . ARG A 1 73 ? 23.832 13.274 -21.385 1.00 100.13 ? 71 ARG A NH1 1 ATOM 378 N NH2 . ARG A 1 73 ? 24.096 12.056 -23.308 1.00 117.86 ? 71 ARG A NH2 1 ATOM 379 N N . ILE A 1 74 ? 16.397 11.449 -19.035 1.00 53.28 ? 72 ILE A N 1 ATOM 380 C CA . ILE A 1 74 ? 15.744 11.186 -17.734 1.00 52.72 ? 72 ILE A CA 1 ATOM 381 C C . ILE A 1 74 ? 15.470 9.667 -17.598 1.00 56.57 ? 72 ILE A C 1 ATOM 382 O O . ILE A 1 74 ? 15.649 9.077 -16.526 1.00 55.24 ? 72 ILE A O 1 ATOM 383 C CB . ILE A 1 74 ? 14.433 12.048 -17.599 1.00 54.77 ? 72 ILE A CB 1 ATOM 384 C CG1 . ILE A 1 74 ? 14.741 13.566 -17.551 1.00 53.92 ? 72 ILE A CG1 1 ATOM 385 C CG2 . ILE A 1 74 ? 13.544 11.606 -16.404 1.00 53.94 ? 72 ILE A CG2 1 ATOM 386 C CD1 . ILE A 1 74 ? 13.520 14.467 -17.768 1.00 53.56 ? 72 ILE A CD1 1 ATOM 387 N N . ASN A 1 75 ? 15.052 9.048 -18.708 1.00 54.14 ? 73 ASN A N 1 ATOM 388 C CA . ASN A 1 75 ? 14.739 7.629 -18.782 1.00 54.11 ? 73 ASN A CA 1 ATOM 389 C C . ASN A 1 75 ? 15.979 6.705 -18.766 1.00 59.37 ? 73 ASN A C 1 ATOM 390 O O . ASN A 1 75 ? 15.810 5.487 -18.757 1.00 59.25 ? 73 ASN A O 1 ATOM 391 C CB . ASN A 1 75 ? 13.836 7.355 -19.973 1.00 52.96 ? 73 ASN A CB 1 ATOM 392 C CG . ASN A 1 75 ? 12.418 7.858 -19.793 1.00 60.24 ? 73 ASN A CG 1 ATOM 393 O OD1 . ASN A 1 75 ? 11.896 7.994 -18.667 1.00 47.29 ? 73 ASN A OD1 1 ATOM 394 N ND2 . ASN A 1 75 ? 11.750 8.098 -20.912 1.00 48.98 ? 73 ASN A ND2 1 ATOM 395 N N . ARG A 1 76 ? 17.204 7.284 -18.722 1.00 56.94 ? 74 ARG A N 1 ATOM 396 C CA . ARG A 1 76 ? 18.513 6.610 -18.612 1.00 57.11 ? 74 ARG A CA 1 ATOM 397 C C . ARG A 1 76 ? 19.129 7.014 -17.264 1.00 63.63 ? 74 ARG A C 1 ATOM 398 O O . ARG A 1 76 ? 20.147 6.446 -16.852 1.00 64.45 ? 74 ARG A O 1 ATOM 399 C CB . ARG A 1 76 ? 19.477 7.065 -19.736 1.00 56.21 ? 74 ARG A CB 1 ATOM 400 C CG . ARG A 1 76 ? 19.295 6.374 -21.080 1.00 67.53 ? 74 ARG A CG 1 ATOM 401 C CD . ARG A 1 76 ? 20.389 6.753 -22.072 1.00 83.24 ? 74 ARG A CD 1 ATOM 402 N NE . ARG A 1 76 ? 20.053 7.969 -22.823 1.00 102.39 ? 74 ARG A NE 1 ATOM 403 C CZ . ARG A 1 76 ? 20.941 8.858 -23.269 1.00 116.45 ? 74 ARG A CZ 1 ATOM 404 N NH1 . ARG A 1 76 ? 22.239 8.679 -23.050 1.00 101.28 ? 74 ARG A NH1 1 ATOM 405 N NH2 . ARG A 1 76 ? 20.535 9.937 -23.926 1.00 100.33 ? 74 ARG A NH2 1 ATOM 406 N N . ASP A 1 77 ? 18.531 8.028 -16.610 1.00 60.92 ? 75 ASP A N 1 ATOM 407 C CA . ASP A 1 77 ? 18.987 8.607 -15.350 1.00 61.54 ? 75 ASP A CA 1 ATOM 408 C C . ASP A 1 77 ? 18.646 7.696 -14.168 1.00 68.08 ? 75 ASP A C 1 ATOM 409 O O . ASP A 1 77 ? 17.478 7.354 -13.987 1.00 67.75 ? 75 ASP A O 1 ATOM 410 C CB . ASP A 1 77 ? 18.394 10.022 -15.160 1.00 63.11 ? 75 ASP A CB 1 ATOM 411 C CG . ASP A 1 77 ? 19.052 10.880 -14.097 1.00 69.32 ? 75 ASP A CG 1 ATOM 412 O OD1 . ASP A 1 77 ? 19.273 10.375 -12.974 1.00 70.96 ? 75 ASP A OD1 1 ATOM 413 O OD2 . ASP A 1 77 ? 19.307 12.069 -14.373 1.00 69.45 ? 75 ASP A OD2 1 ATOM 414 N N . PRO A 1 78 ? 19.653 7.301 -13.344 1.00 67.06 ? 76 PRO A N 1 ATOM 415 C CA . PRO A 1 78 ? 19.369 6.399 -12.214 1.00 66.67 ? 76 PRO A CA 1 ATOM 416 C C . PRO A 1 78 ? 19.112 7.135 -10.906 1.00 68.63 ? 76 PRO A C 1 ATOM 417 O O . PRO A 1 78 ? 18.985 6.502 -9.868 1.00 67.90 ? 76 PRO A O 1 ATOM 418 C CB . PRO A 1 78 ? 20.634 5.528 -12.146 1.00 68.55 ? 76 PRO A CB 1 ATOM 419 C CG . PRO A 1 78 ? 21.729 6.381 -12.744 1.00 73.32 ? 76 PRO A CG 1 ATOM 420 C CD . PRO A 1 78 ? 21.105 7.576 -13.436 1.00 69.19 ? 76 PRO A CD 1 ATOM 421 N N . HIS A 1 79 ? 19.058 8.469 -10.961 1.00 64.77 ? 77 HIS A N 1 ATOM 422 C CA . HIS A 1 79 ? 18.834 9.340 -9.811 1.00 64.22 ? 77 HIS A CA 1 ATOM 423 C C . HIS A 1 79 ? 17.565 10.175 -10.005 1.00 64.10 ? 77 HIS A C 1 ATOM 424 O O . HIS A 1 79 ? 17.194 10.983 -9.148 1.00 64.08 ? 77 HIS A O 1 ATOM 425 C CB . HIS A 1 79 ? 20.082 10.194 -9.569 1.00 65.74 ? 77 HIS A CB 1 ATOM 426 C CG . HIS A 1 79 ? 21.302 9.343 -9.419 1.00 70.37 ? 77 HIS A CG 1 ATOM 427 N ND1 . HIS A 1 79 ? 21.487 8.532 -8.301 1.00 72.51 ? 77 HIS A ND1 1 ATOM 428 C CD2 . HIS A 1 79 ? 22.302 9.105 -10.302 1.00 72.97 ? 77 HIS A CD2 1 ATOM 429 C CE1 . HIS A 1 79 ? 22.615 7.875 -8.519 1.00 72.18 ? 77 HIS A CE1 1 ATOM 430 N NE2 . HIS A 1 79 ? 23.142 8.186 -9.709 1.00 72.75 ? 77 HIS A NE2 1 ATOM 431 N N . LEU A 1 80 ? 16.876 9.926 -11.120 1.00 56.49 ? 78 LEU A N 1 ATOM 432 C CA . LEU A 1 80 ? 15.643 10.590 -11.483 1.00 54.80 ? 78 LEU A CA 1 ATOM 433 C C . LEU A 1 80 ? 14.722 9.550 -12.059 1.00 55.41 ? 78 LEU A C 1 ATOM 434 O O . LEU A 1 80 ? 14.963 8.986 -13.142 1.00 53.54 ? 78 LEU A O 1 ATOM 435 C CB . LEU A 1 80 ? 15.921 11.741 -12.465 1.00 54.82 ? 78 LEU A CB 1 ATOM 436 C CG . LEU A 1 80 ? 14.880 12.829 -12.592 1.00 58.91 ? 78 LEU A CG 1 ATOM 437 C CD1 . LEU A 1 80 ? 14.618 13.516 -11.261 1.00 57.97 ? 78 LEU A CD1 1 ATOM 438 C CD2 . LEU A 1 80 ? 15.339 13.850 -13.594 1.00 63.29 ? 78 LEU A CD2 1 ATOM 439 N N . LEU A 1 81 ? 13.684 9.259 -11.283 1.00 51.64 ? 79 LEU A N 1 ATOM 440 C CA . LEU A 1 81 ? 12.679 8.248 -11.587 1.00 52.46 ? 79 LEU A CA 1 ATOM 441 C C . LEU A 1 81 ? 13.339 6.958 -12.124 1.00 59.76 ? 79 LEU A C 1 ATOM 442 O O . LEU A 1 81 ? 13.126 6.604 -13.285 1.00 61.42 ? 79 LEU A O 1 ATOM 443 C CB . LEU A 1 81 ? 11.593 8.796 -12.541 1.00 52.05 ? 79 LEU A CB 1 ATOM 444 C CG . LEU A 1 81 ? 10.623 9.870 -12.028 1.00 55.61 ? 79 LEU A CG 1 ATOM 445 C CD1 . LEU A 1 81 ? 10.131 9.579 -10.622 1.00 55.56 ? 79 LEU A CD1 1 ATOM 446 C CD2 . LEU A 1 81 ? 11.208 11.234 -12.138 1.00 56.66 ? 79 LEU A CD2 1 ATOM 447 N N . PRO A 1 82 ? 14.213 6.299 -11.322 1.00 56.17 ? 80 PRO A N 1 ATOM 448 C CA . PRO A 1 82 ? 14.895 5.085 -11.811 1.00 55.36 ? 80 PRO A CA 1 ATOM 449 C C . PRO A 1 82 ? 13.980 3.936 -12.216 1.00 56.40 ? 80 PRO A C 1 ATOM 450 O O . PRO A 1 82 ? 14.365 3.148 -13.071 1.00 55.32 ? 80 PRO A O 1 ATOM 451 C CB . PRO A 1 82 ? 15.793 4.679 -10.633 1.00 57.23 ? 80 PRO A CB 1 ATOM 452 C CG . PRO A 1 82 ? 15.909 5.888 -9.786 1.00 61.93 ? 80 PRO A CG 1 ATOM 453 C CD . PRO A 1 82 ? 14.616 6.605 -9.931 1.00 57.94 ? 80 PRO A CD 1 ATOM 454 N N . GLY A 1 83 ? 12.800 3.847 -11.603 1.00 52.33 ? 81 GLY A N 1 ATOM 455 C CA . GLY A 1 83 ? 11.828 2.797 -11.893 1.00 51.74 ? 81 GLY A CA 1 ATOM 456 C C . GLY A 1 83 ? 10.582 3.253 -12.622 1.00 57.08 ? 81 GLY A C 1 ATOM 457 O O . GLY A 1 83 ? 9.861 2.417 -13.171 1.00 58.32 ? 81 GLY A O 1 ATOM 458 N N . VAL A 1 84 ? 10.313 4.585 -12.645 1.00 53.05 ? 82 VAL A N 1 ATOM 459 C CA . VAL A 1 84 ? 9.138 5.186 -13.311 1.00 50.75 ? 82 VAL A CA 1 ATOM 460 C C . VAL A 1 84 ? 9.577 5.743 -14.658 1.00 49.97 ? 82 VAL A C 1 ATOM 461 O O . VAL A 1 84 ? 10.394 6.654 -14.689 1.00 50.67 ? 82 VAL A O 1 ATOM 462 C CB . VAL A 1 84 ? 8.459 6.314 -12.460 1.00 54.38 ? 82 VAL A CB 1 ATOM 463 C CG1 . VAL A 1 84 ? 7.116 6.718 -13.063 1.00 54.32 ? 82 VAL A CG1 1 ATOM 464 C CG2 . VAL A 1 84 ? 8.298 5.931 -10.986 1.00 53.59 ? 82 VAL A CG2 1 ATOM 465 N N . ARG A 1 85 ? 9.048 5.212 -15.757 1.00 43.57 ? 83 ARG A N 1 ATOM 466 C CA . ARG A 1 85 ? 9.358 5.685 -17.101 1.00 42.63 ? 83 ARG A CA 1 ATOM 467 C C . ARG A 1 85 ? 8.398 6.835 -17.496 1.00 48.49 ? 83 ARG A C 1 ATOM 468 O O . ARG A 1 85 ? 7.171 6.726 -17.304 1.00 48.24 ? 83 ARG A O 1 ATOM 469 C CB . ARG A 1 85 ? 9.260 4.538 -18.120 1.00 41.74 ? 83 ARG A CB 1 ATOM 470 C CG . ARG A 1 85 ? 9.541 4.999 -19.558 1.00 57.60 ? 83 ARG A CG 1 ATOM 471 C CD . ARG A 1 85 ? 9.700 3.892 -20.585 1.00 66.79 ? 83 ARG A CD 1 ATOM 472 N NE . ARG A 1 85 ? 10.251 4.407 -21.843 1.00 68.15 ? 83 ARG A NE 1 ATOM 473 C CZ . ARG A 1 85 ? 11.547 4.615 -22.075 1.00 84.25 ? 83 ARG A CZ 1 ATOM 474 N NH1 . ARG A 1 85 ? 11.950 5.098 -23.247 1.00 65.50 ? 83 ARG A NH1 1 ATOM 475 N NH2 . ARG A 1 85 ? 12.450 4.350 -21.135 1.00 78.30 ? 83 ARG A NH2 1 ATOM 476 N N . LEU A 1 86 ? 8.963 7.915 -18.080 1.00 44.44 ? 84 LEU A N 1 ATOM 477 C CA . LEU A 1 86 ? 8.193 9.065 -18.560 1.00 43.74 ? 84 LEU A CA 1 ATOM 478 C C . LEU A 1 86 ? 7.880 9.020 -20.078 1.00 48.90 ? 84 LEU A C 1 ATOM 479 O O . LEU A 1 86 ? 8.788 9.077 -20.921 1.00 48.43 ? 84 LEU A O 1 ATOM 480 C CB . LEU A 1 86 ? 8.862 10.393 -18.180 1.00 43.11 ? 84 LEU A CB 1 ATOM 481 C CG . LEU A 1 86 ? 8.821 10.793 -16.717 1.00 46.85 ? 84 LEU A CG 1 ATOM 482 C CD1 . LEU A 1 86 ? 9.371 12.217 -16.536 1.00 46.85 ? 84 LEU A CD1 1 ATOM 483 C CD2 . LEU A 1 86 ? 7.414 10.723 -16.169 1.00 46.88 ? 84 LEU A CD2 1 ATOM 484 N N . GLY A 1 87 ? 6.589 8.886 -20.379 1.00 44.98 ? 85 GLY A N 1 ATOM 485 C CA . GLY A 1 87 ? 6.022 8.883 -21.718 1.00 43.93 ? 85 GLY A CA 1 ATOM 486 C C . GLY A 1 87 ? 5.577 10.273 -22.157 1.00 47.34 ? 85 GLY A C 1 ATOM 487 O O . GLY A 1 87 ? 5.635 11.238 -21.374 1.00 44.35 ? 85 GLY A O 1 ATOM 488 N N . ALA A 1 88 ? 5.137 10.380 -23.436 1.00 45.08 ? 86 ALA A N 1 ATOM 489 C CA . ALA A 1 88 ? 4.746 11.638 -24.057 1.00 45.01 ? 86 ALA A CA 1 ATOM 490 C C . ALA A 1 88 ? 3.455 11.601 -24.883 1.00 50.32 ? 86 ALA A C 1 ATOM 491 O O . ALA A 1 88 ? 3.035 10.541 -25.366 1.00 50.44 ? 86 ALA A O 1 ATOM 492 C CB . ALA A 1 88 ? 5.884 12.166 -24.905 1.00 45.17 ? 86 ALA A CB 1 ATOM 493 N N . HIS A 1 89 ? 2.841 12.772 -24.975 1.00 45.53 ? 87 HIS A N 1 ATOM 494 C CA . HIS A 1 89 ? 1.703 13.073 -25.821 1.00 44.58 ? 87 HIS A CA 1 ATOM 495 C C . HIS A 1 89 ? 1.836 14.515 -26.263 1.00 47.87 ? 87 HIS A C 1 ATOM 496 O O . HIS A 1 89 ? 1.262 15.392 -25.696 1.00 46.05 ? 87 HIS A O 1 ATOM 497 C CB . HIS A 1 89 ? 0.391 12.885 -25.081 1.00 45.06 ? 87 HIS A CB 1 ATOM 498 C CG . HIS A 1 89 ? -0.802 12.874 -25.972 1.00 48.45 ? 87 HIS A CG 1 ATOM 499 N ND1 . HIS A 1 89 ? -1.562 11.757 -26.162 1.00 50.37 ? 87 HIS A ND1 1 ATOM 500 C CD2 . HIS A 1 89 ? -1.366 13.836 -26.726 1.00 50.39 ? 87 HIS A CD2 1 ATOM 501 C CE1 . HIS A 1 89 ? -2.537 12.022 -27.001 1.00 49.50 ? 87 HIS A CE1 1 ATOM 502 N NE2 . HIS A 1 89 ? -2.439 13.279 -27.360 1.00 49.96 ? 87 HIS A NE2 1 ATOM 503 N N . ILE A 1 90 ? 2.615 14.733 -27.299 1.00 45.16 ? 88 ILE A N 1 ATOM 504 C CA . ILE A 1 90 ? 2.931 16.057 -27.800 1.00 44.45 ? 88 ILE A CA 1 ATOM 505 C C . ILE A 1 90 ? 1.966 16.462 -28.920 1.00 49.40 ? 88 ILE A C 1 ATOM 506 O O . ILE A 1 90 ? 1.688 15.697 -29.853 1.00 48.65 ? 88 ILE A O 1 ATOM 507 C CB . ILE A 1 90 ? 4.425 16.218 -28.163 1.00 46.61 ? 88 ILE A CB 1 ATOM 508 C CG1 . ILE A 1 90 ? 5.294 15.804 -26.945 1.00 47.26 ? 88 ILE A CG1 1 ATOM 509 C CG2 . ILE A 1 90 ? 4.690 17.671 -28.549 1.00 44.92 ? 88 ILE A CG2 1 ATOM 510 C CD1 . ILE A 1 90 ? 6.796 15.557 -27.198 1.00 53.69 ? 88 ILE A CD1 1 ATOM 511 N N . LEU A 1 91 ? 1.406 17.669 -28.760 1.00 44.38 ? 89 LEU A N 1 ATOM 512 C CA . LEU A 1 91 ? 0.435 18.221 -29.658 1.00 42.35 ? 89 LEU A CA 1 ATOM 513 C C . LEU A 1 91 ? 0.994 19.461 -30.310 1.00 45.76 ? 89 LEU A C 1 ATOM 514 O O . LEU A 1 91 ? 1.916 20.093 -29.789 1.00 45.70 ? 89 LEU A O 1 ATOM 515 C CB . LEU A 1 91 ? -0.873 18.468 -28.899 1.00 42.24 ? 89 LEU A CB 1 ATOM 516 C CG . LEU A 1 91 ? -1.613 17.176 -28.493 1.00 46.92 ? 89 LEU A CG 1 ATOM 517 C CD1 . LEU A 1 91 ? -2.674 17.442 -27.461 1.00 47.64 ? 89 LEU A CD1 1 ATOM 518 C CD2 . LEU A 1 91 ? -2.169 16.423 -29.697 1.00 46.45 ? 89 LEU A CD2 1 ATOM 519 N N . ASP A 1 92 ? 0.491 19.763 -31.496 1.00 40.97 ? 90 ASP A N 1 ATOM 520 C CA . ASP A 1 92 ? 0.964 20.888 -32.270 1.00 39.68 ? 90 ASP A CA 1 ATOM 521 C C . ASP A 1 92 ? -0.024 22.045 -32.129 1.00 45.68 ? 90 ASP A C 1 ATOM 522 O O . ASP A 1 92 ? -1.211 21.906 -32.437 1.00 45.94 ? 90 ASP A O 1 ATOM 523 C CB . ASP A 1 92 ? 1.143 20.423 -33.724 1.00 39.61 ? 90 ASP A CB 1 ATOM 524 C CG . ASP A 1 92 ? 1.439 21.457 -34.771 1.00 43.71 ? 90 ASP A CG 1 ATOM 525 O OD1 . ASP A 1 92 ? 1.702 22.622 -34.409 1.00 44.90 ? 90 ASP A OD1 1 ATOM 526 O OD2 . ASP A 1 92 ? 1.435 21.104 -35.946 1.00 53.62 ? 90 ASP A OD2 1 ATOM 527 N N . SER A 1 93 ? 0.454 23.178 -31.646 1.00 42.67 ? 91 SER A N 1 ATOM 528 C CA . SER A 1 93 ? -0.449 24.311 -31.490 1.00 42.66 ? 91 SER A CA 1 ATOM 529 C C . SER A 1 93 ? -0.789 25.017 -32.809 1.00 50.03 ? 91 SER A C 1 ATOM 530 O O . SER A 1 93 ? -1.866 25.620 -32.893 1.00 51.14 ? 91 SER A O 1 ATOM 531 C CB . SER A 1 93 ? 0.109 25.306 -30.483 1.00 41.70 ? 91 SER A CB 1 ATOM 532 O OG . SER A 1 93 ? 1.211 25.983 -31.050 1.00 39.17 ? 91 SER A OG 1 ATOM 533 N N . CYS A 1 94 ? 0.129 24.953 -33.826 1.00 46.82 ? 92 CYS A N 1 ATOM 534 C CA . CYS A 1 94 ? 0.052 25.664 -35.116 1.00 46.69 ? 92 CYS A CA 1 ATOM 535 C C . CYS A 1 94 ? 0.014 27.168 -34.889 1.00 49.28 ? 92 CYS A C 1 ATOM 536 O O . CYS A 1 94 ? -0.627 27.892 -35.661 1.00 47.34 ? 92 CYS A O 1 ATOM 537 C CB . CYS A 1 94 ? -1.132 25.204 -35.955 1.00 48.06 ? 92 CYS A CB 1 ATOM 538 S SG . CYS A 1 94 ? -0.961 23.529 -36.576 1.00 52.72 ? 92 CYS A SG 1 ATOM 539 N N . SER A 1 95 ? 0.667 27.626 -33.774 1.00 45.37 ? 93 SER A N 1 ATOM 540 C CA . SER A 1 95 ? 0.801 29.018 -33.341 1.00 43.89 ? 93 SER A CA 1 ATOM 541 C C . SER A 1 95 ? -0.534 29.755 -33.128 1.00 48.08 ? 93 SER A C 1 ATOM 542 O O . SER A 1 95 ? -0.552 30.997 -33.149 1.00 49.22 ? 93 SER A O 1 ATOM 543 C CB . SER A 1 95 ? 1.682 29.781 -34.328 1.00 45.20 ? 93 SER A CB 1 ATOM 544 O OG . SER A 1 95 ? 2.658 28.929 -34.901 1.00 48.51 ? 93 SER A OG 1 ATOM 545 N N . LYS A 1 96 ? -1.641 29.001 -32.895 1.00 43.19 ? 94 LYS A N 1 ATOM 546 C CA . LYS A 1 96 ? -3.006 29.547 -32.743 1.00 41.94 ? 94 LYS A CA 1 ATOM 547 C C . LYS A 1 96 ? -3.700 29.011 -31.500 1.00 43.93 ? 94 LYS A C 1 ATOM 548 O O . LYS A 1 96 ? -3.810 27.794 -31.318 1.00 44.39 ? 94 LYS A O 1 ATOM 549 C CB . LYS A 1 96 ? -3.821 29.184 -33.989 1.00 44.08 ? 94 LYS A CB 1 ATOM 550 C CG . LYS A 1 96 ? -4.660 30.282 -34.573 1.00 56.38 ? 94 LYS A CG 1 ATOM 551 C CD . LYS A 1 96 ? -5.433 29.707 -35.763 1.00 74.11 ? 94 LYS A CD 1 ATOM 552 C CE . LYS A 1 96 ? -6.736 30.423 -36.061 1.00 91.10 ? 94 LYS A CE 1 ATOM 553 N NZ . LYS A 1 96 ? -7.430 29.861 -37.254 1.00 96.99 ? 94 LYS A NZ 1 ATOM 554 N N . ASP A 1 97 ? -4.172 29.911 -30.643 1.00 40.00 ? 95 ASP A N 1 ATOM 555 C CA . ASP A 1 97 ? -4.851 29.556 -29.390 1.00 39.21 ? 95 ASP A CA 1 ATOM 556 C C . ASP A 1 97 ? -6.062 28.622 -29.614 1.00 43.84 ? 95 ASP A C 1 ATOM 557 O O . ASP A 1 97 ? -6.180 27.605 -28.928 1.00 43.92 ? 95 ASP A O 1 ATOM 558 C CB . ASP A 1 97 ? -5.227 30.811 -28.582 1.00 40.65 ? 95 ASP A CB 1 ATOM 559 C CG . ASP A 1 97 ? -6.095 31.864 -29.291 1.00 50.84 ? 95 ASP A CG 1 ATOM 560 O OD1 . ASP A 1 97 ? -6.510 31.622 -30.452 1.00 49.91 ? 95 ASP A OD1 1 ATOM 561 O OD2 . ASP A 1 97 ? -6.302 32.961 -28.708 1.00 53.78 ? 95 ASP A OD2 1 ATOM 562 N N . THR A 1 98 ? -6.900 28.937 -30.618 1.00 40.47 ? 96 THR A N 1 ATOM 563 C CA . THR A 1 98 ? -8.091 28.180 -30.985 1.00 41.34 ? 96 THR A CA 1 ATOM 564 C C . THR A 1 98 ? -7.728 26.792 -31.463 1.00 48.08 ? 96 THR A C 1 ATOM 565 O O . THR A 1 98 ? -8.517 25.876 -31.278 1.00 48.66 ? 96 THR A O 1 ATOM 566 C CB . THR A 1 98 ? -8.913 28.883 -32.082 1.00 48.16 ? 96 THR A CB 1 ATOM 567 O OG1 . THR A 1 98 ? -8.055 29.239 -33.164 1.00 55.68 ? 96 THR A OG1 1 ATOM 568 C CG2 . THR A 1 98 ? -9.657 30.093 -31.586 1.00 45.61 ? 96 THR A CG2 1 ATOM 569 N N . HIS A 1 99 ? -6.569 26.638 -32.119 1.00 45.05 ? 97 HIS A N 1 ATOM 570 C CA . HIS A 1 99 ? -6.154 25.336 -32.633 1.00 44.62 ? 97 HIS A CA 1 ATOM 571 C C . HIS A 1 99 ? -5.623 24.528 -31.482 1.00 45.85 ? 97 HIS A C 1 ATOM 572 O O . HIS A 1 99 ? -6.050 23.385 -31.291 1.00 42.29 ? 97 HIS A O 1 ATOM 573 C CB . HIS A 1 99 ? -5.109 25.467 -33.761 1.00 45.89 ? 97 HIS A CB 1 ATOM 574 C CG . HIS A 1 99 ? -4.781 24.153 -34.393 1.00 49.70 ? 97 HIS A CG 1 ATOM 575 N ND1 . HIS A 1 99 ? -5.359 23.768 -35.582 1.00 51.41 ? 97 HIS A ND1 1 ATOM 576 C CD2 . HIS A 1 99 ? -4.020 23.137 -33.927 1.00 52.09 ? 97 HIS A CD2 1 ATOM 577 C CE1 . HIS A 1 99 ? -4.892 22.562 -35.835 1.00 51.12 ? 97 HIS A CE1 1 ATOM 578 N NE2 . HIS A 1 99 ? -4.087 22.136 -34.862 1.00 51.88 ? 97 HIS A NE2 1 ATOM 579 N N . ALA A 1 100 ? -4.725 25.150 -30.682 1.00 44.18 ? 98 ALA A N 1 ATOM 580 C CA . ALA A 1 100 ? -4.143 24.527 -29.484 1.00 44.42 ? 98 ALA A CA 1 ATOM 581 C C . ALA A 1 100 ? -5.225 23.982 -28.562 1.00 44.23 ? 98 ALA A C 1 ATOM 582 O O . ALA A 1 100 ? -5.054 22.883 -28.054 1.00 43.08 ? 98 ALA A O 1 ATOM 583 C CB . ALA A 1 100 ? -3.282 25.528 -28.732 1.00 45.32 ? 98 ALA A CB 1 ATOM 584 N N . LEU A 1 101 ? -6.337 24.721 -28.381 1.00 39.98 ? 99 LEU A N 1 ATOM 585 C CA . LEU A 1 101 ? -7.430 24.306 -27.508 1.00 40.76 ? 99 LEU A CA 1 ATOM 586 C C . LEU A 1 101 ? -8.204 23.118 -28.036 1.00 44.04 ? 99 LEU A C 1 ATOM 587 O O . LEU A 1 101 ? -8.633 22.271 -27.245 1.00 43.10 ? 99 LEU A O 1 ATOM 588 C CB . LEU A 1 101 ? -8.369 25.449 -27.144 1.00 41.50 ? 99 LEU A CB 1 ATOM 589 C CG . LEU A 1 101 ? -9.036 25.295 -25.757 1.00 46.52 ? 99 LEU A CG 1 ATOM 590 C CD1 . LEU A 1 101 ? -8.007 25.211 -24.652 1.00 46.64 ? 99 LEU A CD1 1 ATOM 591 C CD2 . LEU A 1 101 ? -10.001 26.428 -25.472 1.00 48.46 ? 99 LEU A CD2 1 ATOM 592 N N . GLU A 1 102 ? -8.351 23.029 -29.369 1.00 40.21 ? 100 GLU A N 1 ATOM 593 C CA . GLU A 1 102 ? -8.998 21.899 -30.031 1.00 39.45 ? 100 GLU A CA 1 ATOM 594 C C . GLU A 1 102 ? -8.182 20.652 -29.688 1.00 43.89 ? 100 GLU A C 1 ATOM 595 O O . GLU A 1 102 ? -8.743 19.670 -29.211 1.00 45.61 ? 100 GLU A O 1 ATOM 596 C CB . GLU A 1 102 ? -9.014 22.098 -31.560 1.00 40.61 ? 100 GLU A CB 1 ATOM 597 C CG . GLU A 1 102 ? -10.054 23.071 -32.080 1.00 44.97 ? 100 GLU A CG 1 ATOM 598 C CD . GLU A 1 102 ? -9.769 23.635 -33.458 1.00 66.93 ? 100 GLU A CD 1 ATOM 599 O OE1 . GLU A 1 102 ? -9.074 22.966 -34.258 1.00 69.92 ? 100 GLU A OE1 1 ATOM 600 O OE2 . GLU A 1 102 ? -10.228 24.766 -33.733 1.00 71.27 ? 100 GLU A OE2 1 ATOM 601 N N . GLN A 1 103 ? -6.848 20.736 -29.864 1.00 38.17 ? 101 GLN A N 1 ATOM 602 C CA . GLN A 1 103 ? -5.885 19.677 -29.592 1.00 36.78 ? 101 GLN A CA 1 ATOM 603 C C . GLN A 1 103 ? -5.765 19.313 -28.126 1.00 40.58 ? 101 GLN A C 1 ATOM 604 O O . GLN A 1 103 ? -5.846 18.127 -27.790 1.00 39.43 ? 101 GLN A O 1 ATOM 605 C CB . GLN A 1 103 ? -4.515 20.033 -30.176 1.00 37.43 ? 101 GLN A CB 1 ATOM 606 C CG . GLN A 1 103 ? -4.530 20.162 -31.695 1.00 33.78 ? 101 GLN A CG 1 ATOM 607 C CD . GLN A 1 103 ? -4.886 18.873 -32.377 1.00 58.42 ? 101 GLN A CD 1 ATOM 608 O OE1 . GLN A 1 103 ? -4.243 17.830 -32.171 1.00 58.67 ? 101 GLN A OE1 1 ATOM 609 N NE2 . GLN A 1 103 ? -5.921 18.923 -33.206 1.00 50.38 ? 101 GLN A NE2 1 ATOM 610 N N . ALA A 1 104 ? -5.618 20.317 -27.239 1.00 37.92 ? 102 ALA A N 1 ATOM 611 C CA . ALA A 1 104 ? -5.490 20.072 -25.792 1.00 38.05 ? 102 ALA A CA 1 ATOM 612 C C . ALA A 1 104 ? -6.635 19.264 -25.177 1.00 40.25 ? 102 ALA A C 1 ATOM 613 O O . ALA A 1 104 ? -6.497 18.836 -24.044 1.00 40.01 ? 102 ALA A O 1 ATOM 614 C CB . ALA A 1 104 ? -5.288 21.373 -25.028 1.00 39.08 ? 102 ALA A CB 1 ATOM 615 N N . LEU A 1 105 ? -7.734 19.003 -25.915 1.00 36.75 ? 103 LEU A N 1 ATOM 616 C CA . LEU A 1 105 ? -8.824 18.175 -25.394 1.00 37.36 ? 103 LEU A CA 1 ATOM 617 C C . LEU A 1 105 ? -8.311 16.733 -25.153 1.00 45.44 ? 103 LEU A C 1 ATOM 618 O O . LEU A 1 105 ? -8.755 16.067 -24.218 1.00 47.60 ? 103 LEU A O 1 ATOM 619 C CB . LEU A 1 105 ? -10.003 18.146 -26.371 1.00 36.87 ? 103 LEU A CB 1 ATOM 620 C CG . LEU A 1 105 ? -10.971 19.312 -26.381 1.00 38.62 ? 103 LEU A CG 1 ATOM 621 C CD1 . LEU A 1 105 ? -12.215 18.897 -27.074 1.00 37.30 ? 103 LEU A CD1 1 ATOM 622 C CD2 . LEU A 1 105 ? -11.329 19.749 -24.998 1.00 37.39 ? 103 LEU A CD2 1 ATOM 623 N N . ASP A 1 106 ? -7.327 16.285 -25.960 1.00 41.11 ? 104 ASP A N 1 ATOM 624 C CA . ASP A 1 106 ? -6.671 14.997 -25.802 1.00 40.98 ? 104 ASP A CA 1 ATOM 625 C C . ASP A 1 106 ? -6.084 14.893 -24.426 1.00 44.06 ? 104 ASP A C 1 ATOM 626 O O . ASP A 1 106 ? -5.897 13.783 -23.926 1.00 45.75 ? 104 ASP A O 1 ATOM 627 C CB . ASP A 1 106 ? -5.529 14.849 -26.812 1.00 43.47 ? 104 ASP A CB 1 ATOM 628 C CG . ASP A 1 106 ? -6.000 14.572 -28.210 1.00 59.54 ? 104 ASP A CG 1 ATOM 629 O OD1 . ASP A 1 106 ? -7.243 14.442 -28.409 1.00 59.80 ? 104 ASP A OD1 1 ATOM 630 O OD2 . ASP A 1 106 ? -5.140 14.527 -29.122 1.00 67.36 ? 104 ASP A OD2 1 ATOM 631 N N . PHE A 1 107 ? -5.774 16.035 -23.818 1.00 38.25 ? 105 PHE A N 1 ATOM 632 C CA . PHE A 1 107 ? -5.197 16.067 -22.489 1.00 37.45 ? 105 PHE A CA 1 ATOM 633 C C . PHE A 1 107 ? -6.186 15.831 -21.360 1.00 42.36 ? 105 PHE A C 1 ATOM 634 O O . PHE A 1 107 ? -5.744 15.507 -20.270 1.00 41.57 ? 105 PHE A O 1 ATOM 635 C CB . PHE A 1 107 ? -4.479 17.396 -22.260 1.00 37.71 ? 105 PHE A CB 1 ATOM 636 C CG . PHE A 1 107 ? -3.231 17.628 -23.063 1.00 37.68 ? 105 PHE A CG 1 ATOM 637 C CD1 . PHE A 1 107 ? -2.444 16.556 -23.481 1.00 40.23 ? 105 PHE A CD1 1 ATOM 638 C CD2 . PHE A 1 107 ? -2.763 18.920 -23.288 1.00 39.49 ? 105 PHE A CD2 1 ATOM 639 C CE1 . PHE A 1 107 ? -1.240 16.770 -24.156 1.00 41.15 ? 105 PHE A CE1 1 ATOM 640 C CE2 . PHE A 1 107 ? -1.572 19.138 -23.982 1.00 43.21 ? 105 PHE A CE2 1 ATOM 641 C CZ . PHE A 1 107 ? -0.802 18.059 -24.392 1.00 41.22 ? 105 PHE A CZ 1 ATOM 642 N N . VAL A 1 108 ? -7.501 16.004 -21.593 1.00 41.76 ? 106 VAL A N 1 ATOM 643 C CA . VAL A 1 108 ? -8.506 15.975 -20.513 1.00 42.92 ? 106 VAL A CA 1 ATOM 644 C C . VAL A 1 108 ? -9.544 14.828 -20.597 1.00 51.47 ? 106 VAL A C 1 ATOM 645 O O . VAL A 1 108 ? -10.315 14.649 -19.645 1.00 50.16 ? 106 VAL A O 1 ATOM 646 C CB . VAL A 1 108 ? -9.217 17.370 -20.374 1.00 46.33 ? 106 VAL A CB 1 ATOM 647 C CG1 . VAL A 1 108 ? -8.205 18.500 -20.163 1.00 45.79 ? 106 VAL A CG1 1 ATOM 648 C CG2 . VAL A 1 108 ? -10.145 17.684 -21.558 1.00 45.80 ? 106 VAL A CG2 1 ATOM 649 N N . ARG A 1 109 ? -9.565 14.060 -21.711 1.00 53.18 ? 107 ARG A N 1 ATOM 650 C CA . ARG A 1 109 ? -10.512 12.947 -21.905 1.00 54.62 ? 107 ARG A CA 1 ATOM 651 C C . ARG A 1 109 ? -10.380 11.827 -20.847 1.00 62.48 ? 107 ARG A C 1 ATOM 652 O O . ARG A 1 109 ? -11.406 11.350 -20.346 1.00 61.62 ? 107 ARG A O 1 ATOM 653 C CB . ARG A 1 109 ? -10.452 12.385 -23.327 1.00 52.80 ? 107 ARG A CB 1 ATOM 654 C CG . ARG A 1 109 ? -10.990 13.360 -24.344 1.00 55.84 ? 107 ARG A CG 1 ATOM 655 C CD . ARG A 1 109 ? -11.579 12.716 -25.593 1.00 62.56 ? 107 ARG A CD 1 ATOM 656 N NE . ARG A 1 109 ? -12.013 13.752 -26.535 1.00 68.85 ? 107 ARG A NE 1 ATOM 657 C CZ . ARG A 1 109 ? -11.243 14.261 -27.497 1.00 79.16 ? 107 ARG A CZ 1 ATOM 658 N NH1 . ARG A 1 109 ? -10.020 13.779 -27.706 1.00 50.03 ? 107 ARG A NH1 1 ATOM 659 N NH2 . ARG A 1 109 ? -11.704 15.232 -28.280 1.00 68.01 ? 107 ARG A NH2 1 ATOM 660 N N . ALA A 1 110 ? -9.140 11.460 -20.459 1.00 62.10 ? 108 ALA A N 1 ATOM 661 C CA . ALA A 1 110 ? -8.916 10.424 -19.436 1.00 63.52 ? 108 ALA A CA 1 ATOM 662 C C . ALA A 1 110 ? -9.478 10.822 -18.071 1.00 71.31 ? 108 ALA A C 1 ATOM 663 O O . ALA A 1 110 ? -9.894 9.952 -17.289 1.00 72.34 ? 108 ALA A O 1 ATOM 664 C CB . ALA A 1 110 ? -7.444 10.119 -19.308 1.00 64.29 ? 108 ALA A CB 1 ATOM 665 N N . SER A 1 111 ? -9.494 12.143 -17.795 1.00 67.89 ? 109 SER A N 1 ATOM 666 C CA . SER A 1 111 ? -10.059 12.720 -16.578 1.00 66.97 ? 109 SER A CA 1 ATOM 667 C C . SER A 1 111 ? -11.597 12.741 -16.660 1.00 70.03 ? 109 SER A C 1 ATOM 668 O O . SER A 1 111 ? -12.250 12.890 -15.629 1.00 70.12 ? 109 SER A O 1 ATOM 669 C CB . SER A 1 111 ? -9.490 14.112 -16.342 1.00 69.79 ? 109 SER A CB 1 ATOM 670 O OG . SER A 1 111 ? -8.079 14.037 -16.218 1.00 76.76 ? 109 SER A OG 1 ATOM 671 N N . LEU A 1 112 ? -12.156 12.548 -17.889 1.00 66.29 ? 110 LEU A N 1 ATOM 672 C CA . LEU A 1 112 ? -13.576 12.456 -18.266 1.00 106.80 ? 110 LEU A CA 1 ATOM 673 C C . LEU A 1 112 ? -14.349 13.744 -18.043 1.00 133.55 ? 110 LEU A C 1 ATOM 674 O O . LEU A 1 112 ? -15.155 14.113 -18.896 1.00 99.31 ? 110 LEU A O 1 ATOM 675 C CB . LEU A 1 112 ? -14.292 11.259 -17.597 1.00 107.11 ? 110 LEU A CB 1 ATOM 676 C CG . LEU A 1 112 ? -13.703 9.855 -17.857 1.00 111.76 ? 110 LEU A CG 1 ATOM 677 C CD1 . LEU A 1 112 ? -13.686 9.014 -16.581 1.00 111.68 ? 110 LEU A CD1 1 ATOM 678 C CD2 . LEU A 1 112 ? -14.448 9.139 -18.970 1.00 113.83 ? 110 LEU A CD2 1 ATOM 679 N N . PRO A 1 135 ? -7.609 5.920 -23.912 1.00 77.58 ? 133 PRO A N 1 ATOM 680 C CA . PRO A 1 135 ? -7.846 6.939 -22.878 1.00 76.84 ? 133 PRO A CA 1 ATOM 681 C C . PRO A 1 135 ? -6.582 7.191 -22.030 1.00 77.50 ? 133 PRO A C 1 ATOM 682 O O . PRO A 1 135 ? -6.485 6.729 -20.883 1.00 77.00 ? 133 PRO A O 1 ATOM 683 C CB . PRO A 1 135 ? -9.024 6.352 -22.072 1.00 78.90 ? 133 PRO A CB 1 ATOM 684 C CG . PRO A 1 135 ? -9.179 4.871 -22.548 1.00 83.56 ? 133 PRO A CG 1 ATOM 685 C CD . PRO A 1 135 ? -8.021 4.578 -23.456 1.00 79.30 ? 133 PRO A CD 1 ATOM 686 N N . THR A 1 136 ? -5.603 7.923 -22.608 1.00 71.05 ? 134 THR A N 1 ATOM 687 C CA . THR A 1 136 ? -4.323 8.212 -21.947 1.00 69.93 ? 134 THR A CA 1 ATOM 688 C C . THR A 1 136 ? -4.429 9.284 -20.837 1.00 68.81 ? 134 THR A C 1 ATOM 689 O O . THR A 1 136 ? -4.821 10.428 -21.100 1.00 69.84 ? 134 THR A O 1 ATOM 690 C CB . THR A 1 136 ? -3.217 8.565 -22.977 1.00 80.01 ? 134 THR A CB 1 ATOM 691 O OG1 . THR A 1 136 ? -3.133 7.531 -23.957 1.00 82.75 ? 134 THR A OG1 1 ATOM 692 C CG2 . THR A 1 136 ? -1.838 8.754 -22.327 1.00 76.49 ? 134 THR A CG2 1 ATOM 693 N N . ALA A 1 137 ? -4.032 8.909 -19.614 1.00 58.70 ? 135 ALA A N 1 ATOM 694 C CA . ALA A 1 137 ? -4.001 9.811 -18.474 1.00 55.24 ? 135 ALA A CA 1 ATOM 695 C C . ALA A 1 137 ? -2.716 10.639 -18.525 1.00 52.64 ? 135 ALA A C 1 ATOM 696 O O . ALA A 1 137 ? -1.620 10.080 -18.556 1.00 50.73 ? 135 ALA A O 1 ATOM 697 C CB . ALA A 1 137 ? -4.086 9.023 -17.187 1.00 55.72 ? 135 ALA A CB 1 ATOM 698 N N . ILE A 1 138 ? -2.872 11.980 -18.595 1.00 45.45 ? 136 ILE A N 1 ATOM 699 C CA . ILE A 1 138 ? -1.805 12.988 -18.669 1.00 41.89 ? 136 ILE A CA 1 ATOM 700 C C . ILE A 1 138 ? -1.553 13.476 -17.248 1.00 43.87 ? 136 ILE A C 1 ATOM 701 O O . ILE A 1 138 ? -2.458 14.002 -16.607 1.00 41.75 ? 136 ILE A O 1 ATOM 702 C CB . ILE A 1 138 ? -2.247 14.098 -19.656 1.00 44.02 ? 136 ILE A CB 1 ATOM 703 C CG1 . ILE A 1 138 ? -2.536 13.525 -21.072 1.00 43.51 ? 136 ILE A CG1 1 ATOM 704 C CG2 . ILE A 1 138 ? -1.299 15.296 -19.706 1.00 45.45 ? 136 ILE A CG2 1 ATOM 705 C CD1 . ILE A 1 138 ? -1.454 12.616 -21.701 1.00 44.12 ? 136 ILE A CD1 1 ATOM 706 N N . THR A 1 139 ? -0.340 13.226 -16.727 1.00 41.71 ? 137 THR A N 1 ATOM 707 C CA . THR A 1 139 ? 0.042 13.571 -15.351 1.00 41.37 ? 137 THR A CA 1 ATOM 708 C C . THR A 1 139 ? 0.438 15.074 -15.196 1.00 46.60 ? 137 THR A C 1 ATOM 709 O O . THR A 1 139 ? 0.315 15.636 -14.096 1.00 48.56 ? 137 THR A O 1 ATOM 710 C CB . THR A 1 139 ? 1.109 12.580 -14.904 1.00 44.32 ? 137 THR A CB 1 ATOM 711 O OG1 . THR A 1 139 ? 0.490 11.300 -14.841 1.00 46.89 ? 137 THR A OG1 1 ATOM 712 C CG2 . THR A 1 139 ? 1.691 12.895 -13.551 1.00 40.66 ? 137 THR A CG2 1 ATOM 713 N N . GLY A 1 140 ? 0.860 15.702 -16.289 1.00 39.52 ? 138 GLY A N 1 ATOM 714 C CA . GLY A 1 140 ? 1.242 17.104 -16.300 1.00 38.91 ? 138 GLY A CA 1 ATOM 715 C C . GLY A 1 140 ? 1.597 17.496 -17.711 1.00 44.50 ? 138 GLY A C 1 ATOM 716 O O . GLY A 1 140 ? 1.903 16.614 -18.532 1.00 45.80 ? 138 GLY A O 1 ATOM 717 N N . VAL A 1 141 ? 1.550 18.812 -18.019 1.00 37.90 ? 139 VAL A N 1 ATOM 718 C CA . VAL A 1 141 ? 1.801 19.310 -19.376 1.00 37.23 ? 139 VAL A CA 1 ATOM 719 C C . VAL A 1 141 ? 2.979 20.286 -19.428 1.00 41.79 ? 139 VAL A C 1 ATOM 720 O O . VAL A 1 141 ? 3.111 21.151 -18.581 1.00 41.02 ? 139 VAL A O 1 ATOM 721 C CB . VAL A 1 141 ? 0.502 19.924 -20.004 1.00 39.70 ? 139 VAL A CB 1 ATOM 722 C CG1 . VAL A 1 141 ? 0.777 20.613 -21.336 1.00 39.38 ? 139 VAL A CG1 1 ATOM 723 C CG2 . VAL A 1 141 ? -0.592 18.886 -20.158 1.00 38.47 ? 139 VAL A CG2 1 ATOM 724 N N . ILE A 1 142 ? 3.821 20.131 -20.432 1.00 39.57 ? 140 ILE A N 1 ATOM 725 C CA . ILE A 1 142 ? 4.952 20.992 -20.692 1.00 39.57 ? 140 ILE A CA 1 ATOM 726 C C . ILE A 1 142 ? 4.534 21.723 -21.918 1.00 46.12 ? 140 ILE A C 1 ATOM 727 O O . ILE A 1 142 ? 4.260 21.096 -22.943 1.00 46.40 ? 140 ILE A O 1 ATOM 728 C CB . ILE A 1 142 ? 6.284 20.239 -20.923 1.00 42.14 ? 140 ILE A CB 1 ATOM 729 C CG1 . ILE A 1 142 ? 6.649 19.315 -19.742 1.00 41.56 ? 140 ILE A CG1 1 ATOM 730 C CG2 . ILE A 1 142 ? 7.420 21.233 -21.266 1.00 43.17 ? 140 ILE A CG2 1 ATOM 731 C CD1 . ILE A 1 142 ? 6.911 20.010 -18.371 1.00 48.65 ? 140 ILE A CD1 1 ATOM 732 N N . GLY A 1 143 ? 4.426 23.036 -21.812 1.00 42.94 ? 141 GLY A N 1 ATOM 733 C CA . GLY A 1 143 ? 4.005 23.754 -22.987 1.00 42.47 ? 141 GLY A CA 1 ATOM 734 C C . GLY A 1 143 ? 3.201 25.029 -22.884 1.00 46.32 ? 141 GLY A C 1 ATOM 735 O O . GLY A 1 143 ? 2.612 25.411 -21.858 1.00 43.34 ? 141 GLY A O 1 ATOM 736 N N . GLY A 1 144 ? 3.097 25.559 -24.080 1.00 44.03 ? 142 GLY A N 1 ATOM 737 C CA . GLY A 1 144 ? 2.584 26.842 -24.425 1.00 43.98 ? 142 GLY A CA 1 ATOM 738 C C . GLY A 1 144 ? 3.842 27.656 -24.625 1.00 46.75 ? 142 GLY A C 1 ATOM 739 O O . GLY A 1 144 ? 4.623 27.816 -23.675 1.00 45.09 ? 142 GLY A O 1 ATOM 740 N N . SER A 1 145 ? 4.092 28.050 -25.895 1.00 41.93 ? 143 SER A N 1 ATOM 741 C CA . SER A 1 145 ? 5.151 28.962 -26.309 1.00 41.67 ? 143 SER A CA 1 ATOM 742 C C . SER A 1 145 ? 4.515 30.400 -26.214 1.00 44.88 ? 143 SER A C 1 ATOM 743 O O . SER A 1 145 ? 4.863 31.185 -25.341 1.00 43.28 ? 143 SER A O 1 ATOM 744 C CB . SER A 1 145 ? 5.581 28.664 -27.750 1.00 44.64 ? 143 SER A CB 1 ATOM 745 O OG . SER A 1 145 ? 6.592 27.682 -27.893 1.00 48.11 ? 143 SER A OG 1 ATOM 746 N N . TYR A 1 146 ? 3.543 30.701 -27.090 1.00 42.25 ? 144 TYR A N 1 ATOM 747 C CA . TYR A 1 146 ? 2.862 31.987 -27.117 1.00 42.27 ? 144 TYR A CA 1 ATOM 748 C C . TYR A 1 146 ? 1.907 32.046 -25.954 1.00 43.32 ? 144 TYR A C 1 ATOM 749 O O . TYR A 1 146 ? 1.307 31.031 -25.595 1.00 43.45 ? 144 TYR A O 1 ATOM 750 C CB . TYR A 1 146 ? 2.182 32.237 -28.479 1.00 45.51 ? 144 TYR A CB 1 ATOM 751 C CG . TYR A 1 146 ? 1.640 33.637 -28.684 1.00 51.35 ? 144 TYR A CG 1 ATOM 752 C CD1 . TYR A 1 146 ? 2.442 34.763 -28.466 1.00 53.35 ? 144 TYR A CD1 1 ATOM 753 C CD2 . TYR A 1 146 ? 0.346 33.841 -29.166 1.00 53.15 ? 144 TYR A CD2 1 ATOM 754 C CE1 . TYR A 1 146 ? 1.941 36.053 -28.637 1.00 52.87 ? 144 TYR A CE1 1 ATOM 755 C CE2 . TYR A 1 146 ? -0.153 35.129 -29.375 1.00 54.29 ? 144 TYR A CE2 1 ATOM 756 C CZ . TYR A 1 146 ? 0.651 36.229 -29.117 1.00 62.75 ? 144 TYR A CZ 1 ATOM 757 O OH . TYR A 1 146 ? 0.147 37.490 -29.316 1.00 67.46 ? 144 TYR A OH 1 ATOM 758 N N . SER A 1 147 ? 1.844 33.211 -25.313 1.00 37.76 ? 145 SER A N 1 ATOM 759 C CA . SER A 1 147 ? 1.092 33.464 -24.098 1.00 36.98 ? 145 SER A CA 1 ATOM 760 C C . SER A 1 147 ? -0.400 33.194 -24.254 1.00 41.10 ? 145 SER A C 1 ATOM 761 O O . SER A 1 147 ? -0.983 32.544 -23.383 1.00 42.23 ? 145 SER A O 1 ATOM 762 C CB . SER A 1 147 ? 1.385 34.869 -23.568 1.00 38.67 ? 145 SER A CB 1 ATOM 763 O OG . SER A 1 147 ? 2.654 34.908 -22.918 1.00 40.19 ? 145 SER A OG 1 ATOM 764 N N . ASP A 1 148 ? -0.999 33.625 -25.371 1.00 35.88 ? 146 ASP A N 1 ATOM 765 C CA . ASP A 1 148 ? -2.410 33.402 -25.670 1.00 35.99 ? 146 ASP A CA 1 ATOM 766 C C . ASP A 1 148 ? -2.715 31.908 -25.540 1.00 38.64 ? 146 ASP A C 1 ATOM 767 O O . ASP A 1 148 ? -3.665 31.518 -24.858 1.00 38.48 ? 146 ASP A O 1 ATOM 768 C CB . ASP A 1 148 ? -2.738 33.927 -27.088 1.00 39.32 ? 146 ASP A CB 1 ATOM 769 C CG . ASP A 1 148 ? -3.228 35.379 -27.169 1.00 62.24 ? 146 ASP A CG 1 ATOM 770 O OD1 . ASP A 1 148 ? -2.764 36.218 -26.354 1.00 63.99 ? 146 ASP A OD1 1 ATOM 771 O OD2 . ASP A 1 148 ? -4.083 35.675 -28.046 1.00 70.70 ? 146 ASP A OD2 1 ATOM 772 N N . VAL A 1 149 ? -1.838 31.080 -26.111 1.00 35.00 ? 147 VAL A N 1 ATOM 773 C CA . VAL A 1 149 ? -1.924 29.617 -26.098 1.00 34.98 ? 147 VAL A CA 1 ATOM 774 C C . VAL A 1 149 ? -1.846 29.052 -24.671 1.00 39.56 ? 147 VAL A C 1 ATOM 775 O O . VAL A 1 149 ? -2.743 28.296 -24.282 1.00 40.54 ? 147 VAL A O 1 ATOM 776 C CB . VAL A 1 149 ? -0.863 28.991 -27.024 1.00 39.16 ? 147 VAL A CB 1 ATOM 777 C CG1 . VAL A 1 149 ? -0.985 27.475 -27.041 1.00 38.87 ? 147 VAL A CG1 1 ATOM 778 C CG2 . VAL A 1 149 ? -0.934 29.576 -28.439 1.00 38.90 ? 147 VAL A CG2 1 ATOM 779 N N . SER A 1 150 ? -0.797 29.430 -23.885 1.00 34.05 ? 148 SER A N 1 ATOM 780 C CA . SER A 1 150 ? -0.677 28.984 -22.499 1.00 33.79 ? 148 SER A CA 1 ATOM 781 C C . SER A 1 150 ? -1.886 29.335 -21.640 1.00 38.18 ? 148 SER A C 1 ATOM 782 O O . SER A 1 150 ? -2.360 28.487 -20.896 1.00 37.88 ? 148 SER A O 1 ATOM 783 C CB . SER A 1 150 ? 0.604 29.489 -21.860 1.00 36.25 ? 148 SER A CB 1 ATOM 784 O OG . SER A 1 150 ? 1.709 28.879 -22.505 1.00 40.75 ? 148 SER A OG 1 ATOM 785 N N . ILE A 1 151 ? -2.411 30.556 -21.789 1.00 35.69 ? 149 ILE A N 1 ATOM 786 C CA . ILE A 1 151 ? -3.596 31.046 -21.087 1.00 35.16 ? 149 ILE A CA 1 ATOM 787 C C . ILE A 1 151 ? -4.845 30.195 -21.421 1.00 38.02 ? 149 ILE A C 1 ATOM 788 O O . ILE A 1 151 ? -5.487 29.692 -20.508 1.00 36.27 ? 149 ILE A O 1 ATOM 789 C CB . ILE A 1 151 ? -3.776 32.564 -21.366 1.00 38.10 ? 149 ILE A CB 1 ATOM 790 C CG1 . ILE A 1 151 ? -2.609 33.332 -20.696 1.00 39.23 ? 149 ILE A CG1 1 ATOM 791 C CG2 . ILE A 1 151 ? -5.135 33.063 -20.832 1.00 36.75 ? 149 ILE A CG2 1 ATOM 792 C CD1 . ILE A 1 151 ? -2.264 34.676 -21.236 1.00 40.06 ? 149 ILE A CD1 1 ATOM 793 N N . GLN A 1 152 ? -5.148 30.023 -22.722 1.00 35.98 ? 150 GLN A N 1 ATOM 794 C CA . GLN A 1 152 ? -6.270 29.245 -23.242 1.00 36.55 ? 150 GLN A CA 1 ATOM 795 C C . GLN A 1 152 ? -6.242 27.815 -22.735 1.00 43.29 ? 150 GLN A C 1 ATOM 796 O O . GLN A 1 152 ? -7.223 27.357 -22.149 1.00 44.37 ? 150 GLN A O 1 ATOM 797 C CB . GLN A 1 152 ? -6.264 29.271 -24.770 1.00 38.14 ? 150 GLN A CB 1 ATOM 798 C CG . GLN A 1 152 ? -6.832 30.547 -25.369 1.00 50.27 ? 150 GLN A CG 1 ATOM 799 C CD . GLN A 1 152 ? -8.212 30.842 -24.838 1.00 61.83 ? 150 GLN A CD 1 ATOM 800 O OE1 . GLN A 1 152 ? -9.161 30.087 -25.119 1.00 54.08 ? 150 GLN A OE1 1 ATOM 801 N NE2 . GLN A 1 152 ? -8.364 31.991 -24.136 1.00 38.41 ? 150 GLN A NE2 1 ATOM 802 N N . VAL A 1 153 ? -5.086 27.147 -22.875 1.00 40.39 ? 151 VAL A N 1 ATOM 803 C CA . VAL A 1 153 ? -4.833 25.791 -22.397 1.00 39.90 ? 151 VAL A CA 1 ATOM 804 C C . VAL A 1 153 ? -4.955 25.696 -20.853 1.00 43.40 ? 151 VAL A C 1 ATOM 805 O O . VAL A 1 153 ? -5.595 24.767 -20.343 1.00 45.50 ? 151 VAL A O 1 ATOM 806 C CB . VAL A 1 153 ? -3.470 25.307 -22.966 1.00 43.64 ? 151 VAL A CB 1 ATOM 807 C CG1 . VAL A 1 153 ? -2.887 24.099 -22.196 1.00 42.67 ? 151 VAL A CG1 1 ATOM 808 C CG2 . VAL A 1 153 ? -3.615 25.003 -24.451 1.00 43.11 ? 151 VAL A CG2 1 ATOM 809 N N . ALA A 1 154 ? -4.406 26.675 -20.126 1.00 36.97 ? 152 ALA A N 1 ATOM 810 C CA . ALA A 1 154 ? -4.480 26.711 -18.658 1.00 36.14 ? 152 ALA A CA 1 ATOM 811 C C . ALA A 1 154 ? -5.909 26.793 -18.150 1.00 42.04 ? 152 ALA A C 1 ATOM 812 O O . ALA A 1 154 ? -6.205 26.229 -17.099 1.00 42.37 ? 152 ALA A O 1 ATOM 813 C CB . ALA A 1 154 ? -3.662 27.865 -18.102 1.00 36.22 ? 152 ALA A CB 1 ATOM 814 N N . ASN A 1 155 ? -6.800 27.467 -18.895 1.00 39.27 ? 153 ASN A N 1 ATOM 815 C CA . ASN A 1 155 ? -8.208 27.582 -18.532 1.00 39.41 ? 153 ASN A CA 1 ATOM 816 C C . ASN A 1 155 ? -8.856 26.208 -18.493 1.00 45.46 ? 153 ASN A C 1 ATOM 817 O O . ASN A 1 155 ? -9.504 25.859 -17.516 1.00 44.72 ? 153 ASN A O 1 ATOM 818 C CB . ASN A 1 155 ? -8.919 28.517 -19.502 1.00 37.50 ? 153 ASN A CB 1 ATOM 819 C CG . ASN A 1 155 ? -8.488 29.961 -19.343 1.00 47.39 ? 153 ASN A CG 1 ATOM 820 O OD1 . ASN A 1 155 ? -8.328 30.464 -18.239 1.00 32.94 ? 153 ASN A OD1 1 ATOM 821 N ND2 . ASN A 1 155 ? -8.278 30.661 -20.440 1.00 38.50 ? 153 ASN A ND2 1 ATOM 822 N N . LEU A 1 156 ? -8.562 25.388 -19.506 1.00 45.74 ? 154 LEU A N 1 ATOM 823 C CA . LEU A 1 156 ? -9.051 24.021 -19.629 1.00 46.15 ? 154 LEU A CA 1 ATOM 824 C C . LEU A 1 156 ? -8.373 23.104 -18.590 1.00 47.49 ? 154 LEU A C 1 ATOM 825 O O . LEU A 1 156 ? -9.055 22.584 -17.702 1.00 47.31 ? 154 LEU A O 1 ATOM 826 C CB . LEU A 1 156 ? -8.855 23.529 -21.079 1.00 46.77 ? 154 LEU A CB 1 ATOM 827 C CG . LEU A 1 156 ? -9.552 22.200 -21.441 1.00 52.24 ? 154 LEU A CG 1 ATOM 828 C CD1 . LEU A 1 156 ? -10.957 22.448 -21.965 1.00 51.63 ? 154 LEU A CD1 1 ATOM 829 C CD2 . LEU A 1 156 ? -8.752 21.450 -22.488 1.00 56.03 ? 154 LEU A CD2 1 ATOM 830 N N . LEU A 1 157 ? -7.027 22.995 -18.638 1.00 40.93 ? 155 LEU A N 1 ATOM 831 C CA . LEU A 1 157 ? -6.213 22.175 -17.724 1.00 38.09 ? 155 LEU A CA 1 ATOM 832 C C . LEU A 1 157 ? -6.566 22.335 -16.232 1.00 38.95 ? 155 LEU A C 1 ATOM 833 O O . LEU A 1 157 ? -6.591 21.357 -15.467 1.00 38.23 ? 155 LEU A O 1 ATOM 834 C CB . LEU A 1 157 ? -4.748 22.503 -17.974 1.00 37.61 ? 155 LEU A CB 1 ATOM 835 C CG . LEU A 1 157 ? -3.935 21.500 -18.798 1.00 41.41 ? 155 LEU A CG 1 ATOM 836 C CD1 . LEU A 1 157 ? -4.644 21.065 -20.093 1.00 40.28 ? 155 LEU A CD1 1 ATOM 837 C CD2 . LEU A 1 157 ? -2.529 22.027 -19.057 1.00 41.89 ? 155 LEU A CD2 1 ATOM 838 N N . ARG A 1 158 ? -6.866 23.567 -15.833 1.00 34.39 ? 156 ARG A N 1 ATOM 839 C CA . ARG A 1 158 ? -7.252 23.934 -14.461 1.00 33.98 ? 156 ARG A CA 1 ATOM 840 C C . ARG A 1 158 ? -8.449 23.109 -13.939 1.00 36.12 ? 156 ARG A C 1 ATOM 841 O O . ARG A 1 158 ? -8.448 22.704 -12.790 1.00 33.10 ? 156 ARG A O 1 ATOM 842 C CB . ARG A 1 158 ? -7.609 25.423 -14.435 1.00 32.89 ? 156 ARG A CB 1 ATOM 843 C CG . ARG A 1 158 ? -7.890 25.923 -13.064 1.00 40.27 ? 156 ARG A CG 1 ATOM 844 C CD . ARG A 1 158 ? -8.523 27.270 -13.086 1.00 47.83 ? 156 ARG A CD 1 ATOM 845 N NE . ARG A 1 158 ? -8.997 27.604 -11.748 1.00 55.32 ? 156 ARG A NE 1 ATOM 846 C CZ . ARG A 1 158 ? -10.236 27.401 -11.318 1.00 63.42 ? 156 ARG A CZ 1 ATOM 847 N NH1 . ARG A 1 158 ? -11.150 26.865 -12.126 1.00 34.73 ? 156 ARG A NH1 1 ATOM 848 N NH2 . ARG A 1 158 ? -10.582 27.760 -10.091 1.00 61.05 ? 156 ARG A NH2 1 ATOM 849 N N . LEU A 1 159 ? -9.459 22.888 -14.799 1.00 34.37 ? 157 LEU A N 1 ATOM 850 C CA . LEU A 1 159 ? -10.693 22.175 -14.491 1.00 34.84 ? 157 LEU A CA 1 ATOM 851 C C . LEU A 1 159 ? -10.489 20.736 -14.074 1.00 39.74 ? 157 LEU A C 1 ATOM 852 O O . LEU A 1 159 ? -11.245 20.222 -13.257 1.00 40.70 ? 157 LEU A O 1 ATOM 853 C CB . LEU A 1 159 ? -11.675 22.275 -15.685 1.00 34.92 ? 157 LEU A CB 1 ATOM 854 C CG . LEU A 1 159 ? -11.947 23.727 -16.180 1.00 38.43 ? 157 LEU A CG 1 ATOM 855 C CD1 . LEU A 1 159 ? -12.416 23.768 -17.663 1.00 38.27 ? 157 LEU A CD1 1 ATOM 856 C CD2 . LEU A 1 159 ? -12.846 24.492 -15.221 1.00 36.97 ? 157 LEU A CD2 1 ATOM 857 N N . PHE A 1 160 ? -9.425 20.126 -14.562 1.00 37.10 ? 158 PHE A N 1 ATOM 858 C CA . PHE A 1 160 ? -9.060 18.733 -14.348 1.00 36.88 ? 158 PHE A CA 1 ATOM 859 C C . PHE A 1 160 ? -7.838 18.554 -13.425 1.00 40.75 ? 158 PHE A C 1 ATOM 860 O O . PHE A 1 160 ? -7.367 17.426 -13.226 1.00 42.01 ? 158 PHE A O 1 ATOM 861 C CB . PHE A 1 160 ? -8.842 18.080 -15.719 1.00 38.96 ? 158 PHE A CB 1 ATOM 862 C CG . PHE A 1 160 ? -10.062 18.210 -16.611 1.00 41.43 ? 158 PHE A CG 1 ATOM 863 C CD1 . PHE A 1 160 ? -11.113 17.292 -16.526 1.00 45.70 ? 158 PHE A CD1 1 ATOM 864 C CD2 . PHE A 1 160 ? -10.188 19.277 -17.496 1.00 42.58 ? 158 PHE A CD2 1 ATOM 865 C CE1 . PHE A 1 160 ? -12.254 17.431 -17.329 1.00 45.75 ? 158 PHE A CE1 1 ATOM 866 C CE2 . PHE A 1 160 ? -11.329 19.417 -18.290 1.00 45.20 ? 158 PHE A CE2 1 ATOM 867 C CZ . PHE A 1 160 ? -12.350 18.490 -18.207 1.00 43.68 ? 158 PHE A CZ 1 ATOM 868 N N . GLN A 1 161 ? -7.339 19.652 -12.850 1.00 35.16 ? 159 GLN A N 1 ATOM 869 C CA . GLN A 1 161 ? -6.191 19.659 -11.929 1.00 35.18 ? 159 GLN A CA 1 ATOM 870 C C . GLN A 1 161 ? -4.864 19.241 -12.585 1.00 38.79 ? 159 GLN A C 1 ATOM 871 O O . GLN A 1 161 ? -3.983 18.762 -11.887 1.00 40.70 ? 159 GLN A O 1 ATOM 872 C CB . GLN A 1 161 ? -6.471 18.819 -10.658 1.00 36.89 ? 159 GLN A CB 1 ATOM 873 C CG . GLN A 1 161 ? -7.629 19.308 -9.783 1.00 50.28 ? 159 GLN A CG 1 ATOM 874 C CD . GLN A 1 161 ? -8.991 19.039 -10.353 1.00 67.80 ? 159 GLN A CD 1 ATOM 875 O OE1 . GLN A 1 161 ? -9.366 17.892 -10.640 1.00 69.54 ? 159 GLN A OE1 1 ATOM 876 N NE2 . GLN A 1 161 ? -9.744 20.105 -10.568 1.00 53.04 ? 159 GLN A NE2 1 ATOM 877 N N . ILE A 1 162 ? -4.687 19.488 -13.898 1.00 33.69 ? 160 ILE A N 1 ATOM 878 C CA . ILE A 1 162 ? -3.474 19.107 -14.601 1.00 32.88 ? 160 ILE A CA 1 ATOM 879 C C . ILE A 1 162 ? -2.392 20.234 -14.564 1.00 38.06 ? 160 ILE A C 1 ATOM 880 O O . ILE A 1 162 ? -2.551 21.277 -15.222 1.00 38.60 ? 160 ILE A O 1 ATOM 881 C CB . ILE A 1 162 ? -3.759 18.567 -16.039 1.00 35.23 ? 160 ILE A CB 1 ATOM 882 C CG1 . ILE A 1 162 ? -4.535 17.217 -15.961 1.00 35.24 ? 160 ILE A CG1 1 ATOM 883 C CG2 . ILE A 1 162 ? -2.448 18.371 -16.819 1.00 34.65 ? 160 ILE A CG2 1 ATOM 884 C CD1 . ILE A 1 162 ? -5.407 16.759 -17.216 1.00 28.45 ? 160 ILE A CD1 1 ATOM 885 N N . PRO A 1 163 ? -1.267 19.986 -13.826 1.00 32.82 ? 161 PRO A N 1 ATOM 886 C CA . PRO A 1 163 ? -0.162 20.960 -13.790 1.00 32.57 ? 161 PRO A CA 1 ATOM 887 C C . PRO A 1 163 ? 0.469 21.198 -15.166 1.00 39.80 ? 161 PRO A C 1 ATOM 888 O O . PRO A 1 163 ? 0.666 20.260 -15.945 1.00 39.93 ? 161 PRO A O 1 ATOM 889 C CB . PRO A 1 163 ? 0.858 20.301 -12.848 1.00 33.43 ? 161 PRO A CB 1 ATOM 890 C CG . PRO A 1 163 ? 0.067 19.353 -12.059 1.00 37.14 ? 161 PRO A CG 1 ATOM 891 C CD . PRO A 1 163 ? -0.938 18.804 -13.006 1.00 32.78 ? 161 PRO A CD 1 ATOM 892 N N . GLN A 1 164 ? 0.791 22.472 -15.442 1.00 36.23 ? 162 GLN A N 1 ATOM 893 C CA . GLN A 1 164 ? 1.352 22.990 -16.690 1.00 34.00 ? 162 GLN A CA 1 ATOM 894 C C . GLN A 1 164 ? 2.632 23.787 -16.432 1.00 38.35 ? 162 GLN A C 1 ATOM 895 O O . GLN A 1 164 ? 2.608 24.738 -15.650 1.00 40.13 ? 162 GLN A O 1 ATOM 896 C CB . GLN A 1 164 ? 0.307 23.925 -17.300 1.00 33.75 ? 162 GLN A CB 1 ATOM 897 C CG . GLN A 1 164 ? 0.674 24.540 -18.625 1.00 28.76 ? 162 GLN A CG 1 ATOM 898 C CD . GLN A 1 164 ? -0.513 25.251 -19.220 1.00 38.10 ? 162 GLN A CD 1 ATOM 899 O OE1 . GLN A 1 164 ? -1.606 25.244 -18.661 1.00 39.72 ? 162 GLN A OE1 1 ATOM 900 N NE2 . GLN A 1 164 ? -0.325 25.919 -20.344 1.00 23.34 ? 162 GLN A NE2 1 ATOM 901 N N . ILE A 1 165 ? 3.727 23.424 -17.089 1.00 33.72 ? 163 ILE A N 1 ATOM 902 C CA . ILE A 1 165 ? 4.980 24.169 -16.991 1.00 33.67 ? 163 ILE A CA 1 ATOM 903 C C . ILE A 1 165 ? 5.318 24.718 -18.356 1.00 34.85 ? 163 ILE A C 1 ATOM 904 O O . ILE A 1 165 ? 5.553 23.949 -19.302 1.00 33.74 ? 163 ILE A O 1 ATOM 905 C CB . ILE A 1 165 ? 6.184 23.438 -16.313 1.00 37.76 ? 163 ILE A CB 1 ATOM 906 C CG1 . ILE A 1 165 ? 5.753 22.772 -14.965 1.00 39.00 ? 163 ILE A CG1 1 ATOM 907 C CG2 . ILE A 1 165 ? 7.365 24.444 -16.099 1.00 37.41 ? 163 ILE A CG2 1 ATOM 908 C CD1 . ILE A 1 165 ? 6.747 21.806 -14.332 1.00 46.43 ? 163 ILE A CD1 1 ATOM 909 N N . SER A 1 166 ? 5.272 26.050 -18.496 1.00 29.51 ? 164 SER A N 1 ATOM 910 C CA . SER A 1 166 ? 5.606 26.628 -19.797 1.00 28.15 ? 164 SER A CA 1 ATOM 911 C C . SER A 1 166 ? 7.089 26.916 -19.861 1.00 31.30 ? 164 SER A C 1 ATOM 912 O O . SER A 1 166 ? 7.722 27.161 -18.848 1.00 29.84 ? 164 SER A O 1 ATOM 913 C CB . SER A 1 166 ? 4.763 27.864 -20.091 1.00 32.01 ? 164 SER A CB 1 ATOM 914 O OG . SER A 1 166 ? 5.242 28.609 -21.202 1.00 46.14 ? 164 SER A OG 1 ATOM 915 N N . TYR A 1 167 ? 7.654 26.835 -21.042 1.00 31.55 ? 165 TYR A N 1 ATOM 916 C CA . TYR A 1 167 ? 9.073 27.104 -21.270 1.00 32.73 ? 165 TYR A CA 1 ATOM 917 C C . TYR A 1 167 ? 9.283 28.472 -21.965 1.00 41.84 ? 165 TYR A C 1 ATOM 918 O O . TYR A 1 167 ? 10.429 28.882 -22.102 1.00 43.64 ? 165 TYR A O 1 ATOM 919 C CB . TYR A 1 167 ? 9.657 25.993 -22.144 1.00 32.92 ? 165 TYR A CB 1 ATOM 920 C CG . TYR A 1 167 ? 8.791 25.698 -23.353 1.00 33.82 ? 165 TYR A CG 1 ATOM 921 C CD1 . TYR A 1 167 ? 8.824 26.517 -24.479 1.00 34.44 ? 165 TYR A CD1 1 ATOM 922 C CD2 . TYR A 1 167 ? 7.910 24.623 -23.357 1.00 35.30 ? 165 TYR A CD2 1 ATOM 923 C CE1 . TYR A 1 167 ? 8.014 26.263 -25.582 1.00 32.83 ? 165 TYR A CE1 1 ATOM 924 C CE2 . TYR A 1 167 ? 7.049 24.400 -24.426 1.00 36.44 ? 165 TYR A CE2 1 ATOM 925 C CZ . TYR A 1 167 ? 7.110 25.219 -25.540 1.00 40.32 ? 165 TYR A CZ 1 ATOM 926 O OH . TYR A 1 167 ? 6.286 24.967 -26.597 1.00 39.07 ? 165 TYR A OH 1 ATOM 927 N N . ALA A 1 168 ? 8.211 29.148 -22.458 1.00 39.60 ? 166 ALA A N 1 ATOM 928 C CA . ALA A 1 168 ? 8.395 30.404 -23.199 1.00 39.72 ? 166 ALA A CA 1 ATOM 929 C C . ALA A 1 168 ? 7.358 31.517 -22.971 1.00 43.21 ? 166 ALA A C 1 ATOM 930 O O . ALA A 1 168 ? 7.608 32.645 -23.443 1.00 41.93 ? 166 ALA A O 1 ATOM 931 C CB . ALA A 1 168 ? 8.478 30.107 -24.687 1.00 40.50 ? 166 ALA A CB 1 ATOM 932 N N . SER A 1 169 ? 6.200 31.217 -22.293 1.00 38.71 ? 167 SER A N 1 ATOM 933 C CA . SER A 1 169 ? 5.118 32.206 -22.103 1.00 37.89 ? 167 SER A CA 1 ATOM 934 C C . SER A 1 169 ? 5.423 33.132 -20.957 1.00 41.28 ? 167 SER A C 1 ATOM 935 O O . SER A 1 169 ? 5.525 32.669 -19.830 1.00 38.95 ? 167 SER A O 1 ATOM 936 C CB . SER A 1 169 ? 3.761 31.533 -21.932 1.00 39.96 ? 167 SER A CB 1 ATOM 937 O OG . SER A 1 169 ? 3.531 30.667 -23.026 1.00 45.17 ? 167 SER A OG 1 ATOM 938 N N . THR A 1 170 ? 5.544 34.450 -21.247 1.00 38.54 ? 168 THR A N 1 ATOM 939 C CA . THR A 1 170 ? 5.975 35.464 -20.291 1.00 37.75 ? 168 THR A CA 1 ATOM 940 C C . THR A 1 170 ? 4.930 36.479 -19.836 1.00 42.22 ? 168 THR A C 1 ATOM 941 O O . THR A 1 170 ? 5.230 37.266 -18.939 1.00 42.63 ? 168 THR A O 1 ATOM 942 C CB . THR A 1 170 ? 7.188 36.189 -20.847 1.00 43.78 ? 168 THR A CB 1 ATOM 943 O OG1 . THR A 1 170 ? 6.844 36.748 -22.106 1.00 41.84 ? 168 THR A OG1 1 ATOM 944 C CG2 . THR A 1 170 ? 8.414 35.296 -20.972 1.00 42.45 ? 168 THR A CG2 1 ATOM 945 N N . SER A 1 171 ? 3.705 36.455 -20.384 1.00 39.68 ? 169 SER A N 1 ATOM 946 C CA . SER A 1 171 ? 2.627 37.374 -19.949 1.00 37.91 ? 169 SER A CA 1 ATOM 947 C C . SER A 1 171 ? 2.464 37.380 -18.420 1.00 41.88 ? 169 SER A C 1 ATOM 948 O O . SER A 1 171 ? 2.450 36.327 -17.782 1.00 41.82 ? 169 SER A O 1 ATOM 949 C CB . SER A 1 171 ? 1.301 36.962 -20.567 1.00 38.13 ? 169 SER A CB 1 ATOM 950 O OG . SER A 1 171 ? 0.278 37.875 -20.206 1.00 44.68 ? 169 SER A OG 1 ATOM 951 N N . ALA A 1 172 ? 2.308 38.559 -17.847 1.00 38.18 ? 170 ALA A N 1 ATOM 952 C CA . ALA A 1 172 ? 2.130 38.715 -16.409 1.00 38.39 ? 170 ALA A CA 1 ATOM 953 C C . ALA A 1 172 ? 0.781 38.149 -15.957 1.00 42.99 ? 170 ALA A C 1 ATOM 954 O O . ALA A 1 172 ? 0.602 37.797 -14.781 1.00 42.31 ? 170 ALA A O 1 ATOM 955 C CB . ALA A 1 172 ? 2.209 40.182 -16.051 1.00 39.16 ? 170 ALA A CB 1 ATOM 956 N N . LYS A 1 173 ? -0.164 38.072 -16.910 1.00 39.07 ? 171 LYS A N 1 ATOM 957 C CA . LYS A 1 173 ? -1.520 37.581 -16.723 1.00 38.91 ? 171 LYS A CA 1 ATOM 958 C C . LYS A 1 173 ? -1.433 36.201 -16.126 1.00 43.81 ? 171 LYS A C 1 ATOM 959 O O . LYS A 1 173 ? -2.157 35.919 -15.181 1.00 44.99 ? 171 LYS A O 1 ATOM 960 C CB . LYS A 1 173 ? -2.282 37.582 -18.069 1.00 41.56 ? 171 LYS A CB 1 ATOM 961 C CG . LYS A 1 173 ? -3.800 37.496 -17.947 1.00 62.43 ? 171 LYS A CG 1 ATOM 962 C CD . LYS A 1 173 ? -4.469 37.760 -19.293 1.00 71.96 ? 171 LYS A CD 1 ATOM 963 C CE . LYS A 1 173 ? -5.961 37.513 -19.268 1.00 84.05 ? 171 LYS A CE 1 ATOM 964 N NZ . LYS A 1 173 ? -6.593 37.765 -20.599 1.00 91.48 ? 171 LYS A NZ 1 ATOM 965 N N . LEU A 1 174 ? -0.473 35.377 -16.599 1.00 39.38 ? 172 LEU A N 1 ATOM 966 C CA . LEU A 1 174 ? -0.278 34.022 -16.091 1.00 38.67 ? 172 LEU A CA 1 ATOM 967 C C . LEU A 1 174 ? 0.143 33.924 -14.629 1.00 41.65 ? 172 LEU A C 1 ATOM 968 O O . LEU A 1 174 ? 0.059 32.828 -14.075 1.00 42.23 ? 172 LEU A O 1 ATOM 969 C CB . LEU A 1 174 ? 0.704 33.256 -16.962 1.00 38.52 ? 172 LEU A CB 1 ATOM 970 C CG . LEU A 1 174 ? 0.118 32.751 -18.258 1.00 42.58 ? 172 LEU A CG 1 ATOM 971 C CD1 . LEU A 1 174 ? 1.195 32.577 -19.305 1.00 42.13 ? 172 LEU A CD1 1 ATOM 972 C CD2 . LEU A 1 174 ? -0.736 31.491 -18.038 1.00 43.41 ? 172 LEU A CD2 1 ATOM 973 N N . SER A 1 175 ? 0.584 35.042 -14.002 1.00 37.49 ? 173 SER A N 1 ATOM 974 C CA . SER A 1 175 ? 1.026 35.055 -12.586 1.00 37.77 ? 173 SER A CA 1 ATOM 975 C C . SER A 1 175 ? -0.136 35.060 -11.610 1.00 42.00 ? 173 SER A C 1 ATOM 976 O O . SER A 1 175 ? 0.093 34.899 -10.418 1.00 41.09 ? 173 SER A O 1 ATOM 977 C CB . SER A 1 175 ? 1.979 36.212 -12.284 1.00 39.46 ? 173 SER A CB 1 ATOM 978 O OG . SER A 1 175 ? 3.287 36.010 -12.789 1.00 42.82 ? 173 SER A OG 1 ATOM 979 N N . ASP A 1 176 ? -1.379 35.236 -12.117 1.00 40.35 ? 174 ASP A N 1 ATOM 980 C CA . ASP A 1 176 ? -2.624 35.243 -11.338 1.00 40.25 ? 174 ASP A CA 1 ATOM 981 C C . ASP A 1 176 ? -3.091 33.795 -10.992 1.00 47.32 ? 174 ASP A C 1 ATOM 982 O O . ASP A 1 176 ? -3.646 33.079 -11.849 1.00 46.04 ? 174 ASP A O 1 ATOM 983 C CB . ASP A 1 176 ? -3.710 35.987 -12.102 1.00 40.84 ? 174 ASP A CB 1 ATOM 984 C CG . ASP A 1 176 ? -4.951 36.205 -11.289 1.00 54.42 ? 174 ASP A CG 1 ATOM 985 O OD1 . ASP A 1 176 ? -4.968 35.791 -10.104 1.00 53.56 ? 174 ASP A OD1 1 ATOM 986 O OD2 . ASP A 1 176 ? -5.908 36.809 -11.824 1.00 66.50 ? 174 ASP A OD2 1 ATOM 987 N N . LYS A 1 177 ? -2.889 33.404 -9.707 1.00 42.96 ? 175 LYS A N 1 ATOM 988 C CA . LYS A 1 177 ? -3.221 32.071 -9.187 1.00 40.55 ? 175 LYS A CA 1 ATOM 989 C C . LYS A 1 177 ? -4.704 31.884 -8.915 1.00 40.09 ? 175 LYS A C 1 ATOM 990 O O . LYS A 1 177 ? -5.155 30.732 -8.761 1.00 37.64 ? 175 LYS A O 1 ATOM 991 C CB . LYS A 1 177 ? -2.359 31.683 -7.955 1.00 39.34 ? 175 LYS A CB 1 ATOM 992 C CG . LYS A 1 177 ? -0.869 31.638 -8.246 1.00 32.55 ? 175 LYS A CG 1 ATOM 993 C CD . LYS A 1 177 ? -0.495 30.729 -9.454 1.00 45.46 ? 175 LYS A CD 1 ATOM 994 C CE . LYS A 1 177 ? -0.205 31.498 -10.723 1.00 43.24 ? 175 LYS A CE 1 ATOM 995 N NZ . LYS A 1 177 ? 0.482 30.643 -11.704 1.00 45.88 ? 175 LYS A NZ 1 ATOM 996 N N . SER A 1 178 ? -5.460 32.990 -8.879 1.00 35.17 ? 176 SER A N 1 ATOM 997 C CA . SER A 1 178 ? -6.916 32.917 -8.673 1.00 35.89 ? 176 SER A CA 1 ATOM 998 C C . SER A 1 178 ? -7.551 32.306 -9.930 1.00 43.00 ? 176 SER A C 1 ATOM 999 O O . SER A 1 178 ? -8.653 31.770 -9.839 1.00 43.73 ? 176 SER A O 1 ATOM 1000 C CB . SER A 1 178 ? -7.512 34.298 -8.378 1.00 38.16 ? 176 SER A CB 1 ATOM 1001 O OG . SER A 1 178 ? -7.891 35.025 -9.541 1.00 45.31 ? 176 SER A OG 1 ATOM 1002 N N . ARG A 1 179 ? -6.834 32.372 -11.103 1.00 40.43 ? 177 ARG A N 1 ATOM 1003 C CA . ARG A 1 179 ? -7.303 31.805 -12.377 1.00 39.75 ? 177 ARG A CA 1 ATOM 1004 C C . ARG A 1 179 ? -6.321 30.854 -13.091 1.00 43.68 ? 177 ARG A C 1 ATOM 1005 O O . ARG A 1 179 ? -6.763 30.065 -13.933 1.00 44.90 ? 177 ARG A O 1 ATOM 1006 C CB . ARG A 1 179 ? -7.782 32.881 -13.339 1.00 40.42 ? 177 ARG A CB 1 ATOM 1007 C CG . ARG A 1 179 ? -6.873 34.046 -13.508 1.00 49.19 ? 177 ARG A CG 1 ATOM 1008 C CD . ARG A 1 179 ? -7.367 34.907 -14.630 1.00 59.67 ? 177 ARG A CD 1 ATOM 1009 N NE . ARG A 1 179 ? -8.578 35.629 -14.281 1.00 69.69 ? 177 ARG A NE 1 ATOM 1010 C CZ . ARG A 1 179 ? -9.751 35.421 -14.855 1.00 97.19 ? 177 ARG A CZ 1 ATOM 1011 N NH1 . ARG A 1 179 ? -10.805 36.138 -14.495 1.00 97.58 ? 177 ARG A NH1 1 ATOM 1012 N NH2 . ARG A 1 179 ? -9.881 34.498 -15.805 1.00 82.44 ? 177 ARG A NH2 1 ATOM 1013 N N . TYR A 1 180 ? -5.019 30.893 -12.764 1.00 39.07 ? 178 TYR A N 1 ATOM 1014 C CA . TYR A 1 180 ? -4.038 29.967 -13.353 1.00 37.37 ? 178 TYR A CA 1 ATOM 1015 C C . TYR A 1 180 ? -3.334 29.256 -12.221 1.00 42.65 ? 178 TYR A C 1 ATOM 1016 O O . TYR A 1 180 ? -2.111 29.222 -12.169 1.00 43.83 ? 178 TYR A O 1 ATOM 1017 C CB . TYR A 1 180 ? -3.063 30.664 -14.348 1.00 36.67 ? 178 TYR A CB 1 ATOM 1018 C CG . TYR A 1 180 ? -3.752 31.625 -15.300 1.00 35.59 ? 178 TYR A CG 1 ATOM 1019 C CD1 . TYR A 1 180 ? -4.645 31.160 -16.273 1.00 35.36 ? 178 TYR A CD1 1 ATOM 1020 C CD2 . TYR A 1 180 ? -3.587 33.008 -15.170 1.00 34.95 ? 178 TYR A CD2 1 ATOM 1021 C CE1 . TYR A 1 180 ? -5.347 32.041 -17.088 1.00 32.04 ? 178 TYR A CE1 1 ATOM 1022 C CE2 . TYR A 1 180 ? -4.252 33.896 -16.012 1.00 34.61 ? 178 TYR A CE2 1 ATOM 1023 C CZ . TYR A 1 180 ? -5.134 33.408 -16.966 1.00 40.33 ? 178 TYR A CZ 1 ATOM 1024 O OH . TYR A 1 180 ? -5.840 34.289 -17.737 1.00 40.30 ? 178 TYR A OH 1 ATOM 1025 N N . ASP A 1 181 ? -4.121 28.651 -11.318 1.00 40.95 ? 179 ASP A N 1 ATOM 1026 C CA . ASP A 1 181 ? -3.618 27.956 -10.117 1.00 40.27 ? 179 ASP A CA 1 ATOM 1027 C C . ASP A 1 181 ? -2.794 26.704 -10.405 1.00 40.32 ? 179 ASP A C 1 ATOM 1028 O O . ASP A 1 181 ? -2.010 26.327 -9.542 1.00 39.64 ? 179 ASP A O 1 ATOM 1029 C CB . ASP A 1 181 ? -4.728 27.640 -9.089 1.00 42.40 ? 179 ASP A CB 1 ATOM 1030 C CG . ASP A 1 181 ? -6.130 27.539 -9.631 1.00 60.84 ? 179 ASP A CG 1 ATOM 1031 O OD1 . ASP A 1 181 ? -6.356 26.702 -10.508 1.00 62.68 ? 179 ASP A OD1 1 ATOM 1032 O OD2 . ASP A 1 181 ? -7.004 28.308 -9.170 1.00 71.08 ? 179 ASP A OD2 1 ATOM 1033 N N . TYR A 1 182 ? -2.886 26.113 -11.601 1.00 36.53 ? 180 TYR A N 1 ATOM 1034 C CA . TYR A 1 182 ? -2.086 24.910 -11.922 1.00 37.48 ? 180 TYR A CA 1 ATOM 1035 C C . TYR A 1 182 ? -0.931 25.196 -12.908 1.00 39.48 ? 180 TYR A C 1 ATOM 1036 O O . TYR A 1 182 ? -0.284 24.269 -13.451 1.00 37.25 ? 180 TYR A O 1 ATOM 1037 C CB . TYR A 1 182 ? -2.996 23.773 -12.432 1.00 39.96 ? 180 TYR A CB 1 ATOM 1038 C CG . TYR A 1 182 ? -3.829 23.165 -11.338 1.00 43.50 ? 180 TYR A CG 1 ATOM 1039 C CD1 . TYR A 1 182 ? -3.343 22.111 -10.574 1.00 47.26 ? 180 TYR A CD1 1 ATOM 1040 C CD2 . TYR A 1 182 ? -5.080 23.688 -11.012 1.00 44.25 ? 180 TYR A CD2 1 ATOM 1041 C CE1 . TYR A 1 182 ? -4.088 21.583 -9.515 1.00 51.68 ? 180 TYR A CE1 1 ATOM 1042 C CE2 . TYR A 1 182 ? -5.826 23.181 -9.949 1.00 44.96 ? 180 TYR A CE2 1 ATOM 1043 C CZ . TYR A 1 182 ? -5.339 22.107 -9.222 1.00 56.58 ? 180 TYR A CZ 1 ATOM 1044 O OH . TYR A 1 182 ? -6.075 21.589 -8.185 1.00 60.06 ? 180 TYR A OH 1 ATOM 1045 N N . PHE A 1 183 ? -0.678 26.486 -13.128 1.00 35.26 ? 181 PHE A N 1 ATOM 1046 C CA . PHE A 1 183 ? 0.336 26.892 -14.087 1.00 35.87 ? 181 PHE A CA 1 ATOM 1047 C C . PHE A 1 183 ? 1.597 27.399 -13.431 1.00 39.78 ? 181 PHE A C 1 ATOM 1048 O O . PHE A 1 183 ? 1.518 28.131 -12.463 1.00 40.75 ? 181 PHE A O 1 ATOM 1049 C CB . PHE A 1 183 ? -0.242 27.948 -15.052 1.00 37.29 ? 181 PHE A CB 1 ATOM 1050 C CG . PHE A 1 183 ? 0.728 28.490 -16.067 1.00 37.98 ? 181 PHE A CG 1 ATOM 1051 C CD1 . PHE A 1 183 ? 1.545 29.573 -15.765 1.00 42.12 ? 181 PHE A CD1 1 ATOM 1052 C CD2 . PHE A 1 183 ? 0.819 27.933 -17.323 1.00 38.22 ? 181 PHE A CD2 1 ATOM 1053 C CE1 . PHE A 1 183 ? 2.482 30.040 -16.686 1.00 42.67 ? 181 PHE A CE1 1 ATOM 1054 C CE2 . PHE A 1 183 ? 1.719 28.428 -18.257 1.00 41.20 ? 181 PHE A CE2 1 ATOM 1055 C CZ . PHE A 1 183 ? 2.549 29.476 -17.932 1.00 40.07 ? 181 PHE A CZ 1 ATOM 1056 N N . ALA A 1 184 ? 2.749 27.053 -14.008 1.00 34.91 ? 182 ALA A N 1 ATOM 1057 C CA . ALA A 1 184 ? 4.084 27.511 -13.645 1.00 34.69 ? 182 ALA A CA 1 ATOM 1058 C C . ALA A 1 184 ? 4.906 27.574 -14.920 1.00 39.93 ? 182 ALA A C 1 ATOM 1059 O O . ALA A 1 184 ? 4.474 27.073 -15.978 1.00 39.30 ? 182 ALA A O 1 ATOM 1060 C CB . ALA A 1 184 ? 4.730 26.576 -12.654 1.00 35.94 ? 182 ALA A CB 1 ATOM 1061 N N . ARG A 1 185 ? 6.092 28.198 -14.836 1.00 36.35 ? 183 ARG A N 1 ATOM 1062 C CA . ARG A 1 185 ? 6.947 28.385 -15.996 1.00 35.39 ? 183 ARG A CA 1 ATOM 1063 C C . ARG A 1 185 ? 8.392 28.482 -15.620 1.00 42.41 ? 183 ARG A C 1 ATOM 1064 O O . ARG A 1 185 ? 8.710 29.014 -14.563 1.00 45.61 ? 183 ARG A O 1 ATOM 1065 C CB . ARG A 1 185 ? 6.524 29.664 -16.742 1.00 33.56 ? 183 ARG A CB 1 ATOM 1066 C CG . ARG A 1 185 ? 6.075 30.817 -15.839 1.00 36.60 ? 183 ARG A CG 1 ATOM 1067 C CD . ARG A 1 185 ? 6.057 32.131 -16.586 1.00 39.20 ? 183 ARG A CD 1 ATOM 1068 N NE . ARG A 1 185 ? 5.273 33.160 -15.898 1.00 37.79 ? 183 ARG A NE 1 ATOM 1069 C CZ . ARG A 1 185 ? 4.447 34.011 -16.502 1.00 45.64 ? 183 ARG A CZ 1 ATOM 1070 N NH1 . ARG A 1 185 ? 3.785 34.915 -15.797 1.00 27.88 ? 183 ARG A NH1 1 ATOM 1071 N NH2 . ARG A 1 185 ? 4.278 33.965 -17.817 1.00 41.67 ? 183 ARG A NH2 1 ATOM 1072 N N . THR A 1 186 ? 9.284 28.066 -16.514 1.00 38.28 ? 184 THR A N 1 ATOM 1073 C CA . THR A 1 186 ? 10.729 28.162 -16.298 1.00 37.35 ? 184 THR A CA 1 ATOM 1074 C C . THR A 1 186 ? 11.296 29.503 -16.776 1.00 43.22 ? 184 THR A C 1 ATOM 1075 O O . THR A 1 186 ? 12.516 29.728 -16.698 1.00 44.12 ? 184 THR A O 1 ATOM 1076 C CB . THR A 1 186 ? 11.442 26.962 -16.887 1.00 41.27 ? 184 THR A CB 1 ATOM 1077 O OG1 . THR A 1 186 ? 10.998 26.781 -18.236 1.00 43.44 ? 184 THR A OG1 1 ATOM 1078 C CG2 . THR A 1 186 ? 11.204 25.703 -16.062 1.00 38.99 ? 184 THR A CG2 1 ATOM 1079 N N . VAL A 1 187 ? 10.411 30.408 -17.220 1.00 38.86 ? 185 VAL A N 1 ATOM 1080 C CA . VAL A 1 187 ? 10.775 31.757 -17.648 1.00 38.53 ? 185 VAL A CA 1 ATOM 1081 C C . VAL A 1 187 ? 10.241 32.781 -16.645 1.00 44.15 ? 185 VAL A C 1 ATOM 1082 O O . VAL A 1 187 ? 9.255 32.503 -15.949 1.00 44.25 ? 185 VAL A O 1 ATOM 1083 C CB . VAL A 1 187 ? 10.349 32.123 -19.103 1.00 41.99 ? 185 VAL A CB 1 ATOM 1084 C CG1 . VAL A 1 187 ? 11.196 31.388 -20.144 1.00 41.87 ? 185 VAL A CG1 1 ATOM 1085 C CG2 . VAL A 1 187 ? 8.843 31.949 -19.341 1.00 41.34 ? 185 VAL A CG2 1 ATOM 1086 N N . PRO A 1 188 ? 10.807 34.005 -16.605 1.00 41.38 ? 186 PRO A N 1 ATOM 1087 C CA . PRO A 1 188 ? 10.283 35.002 -15.671 1.00 41.38 ? 186 PRO A CA 1 ATOM 1088 C C . PRO A 1 188 ? 9.052 35.714 -16.228 1.00 46.06 ? 186 PRO A C 1 ATOM 1089 O O . PRO A 1 188 ? 8.897 35.794 -17.457 1.00 46.74 ? 186 PRO A O 1 ATOM 1090 C CB . PRO A 1 188 ? 11.461 35.981 -15.520 1.00 42.89 ? 186 PRO A CB 1 ATOM 1091 C CG . PRO A 1 188 ? 12.592 35.403 -16.336 1.00 46.66 ? 186 PRO A CG 1 ATOM 1092 C CD . PRO A 1 188 ? 11.969 34.543 -17.340 1.00 42.29 ? 186 PRO A CD 1 ATOM 1093 N N . PRO A 1 189 ? 8.198 36.314 -15.367 1.00 42.05 ? 187 PRO A N 1 ATOM 1094 C CA . PRO A 1 189 ? 7.066 37.104 -15.901 1.00 41.54 ? 187 PRO A CA 1 ATOM 1095 C C . PRO A 1 189 ? 7.591 38.409 -16.518 1.00 45.61 ? 187 PRO A C 1 ATOM 1096 O O . PRO A 1 189 ? 8.719 38.844 -16.197 1.00 45.43 ? 187 PRO A O 1 ATOM 1097 C CB . PRO A 1 189 ? 6.210 37.382 -14.663 1.00 42.38 ? 187 PRO A CB 1 ATOM 1098 C CG . PRO A 1 189 ? 7.126 37.296 -13.540 1.00 45.95 ? 187 PRO A CG 1 ATOM 1099 C CD . PRO A 1 189 ? 8.248 36.375 -13.889 1.00 41.92 ? 187 PRO A CD 1 ATOM 1100 N N . ASP A 1 190 ? 6.774 39.043 -17.377 1.00 40.32 ? 188 ASP A N 1 ATOM 1101 C CA . ASP A 1 190 ? 7.179 40.238 -18.096 1.00 40.08 ? 188 ASP A CA 1 ATOM 1102 C C . ASP A 1 190 ? 7.194 41.536 -17.304 1.00 43.65 ? 188 ASP A C 1 ATOM 1103 O O . ASP A 1 190 ? 7.579 42.554 -17.881 1.00 42.60 ? 188 ASP A O 1 ATOM 1104 C CB . ASP A 1 190 ? 6.392 40.424 -19.382 1.00 42.45 ? 188 ASP A CB 1 ATOM 1105 C CG . ASP A 1 190 ? 6.990 39.624 -20.514 1.00 45.47 ? 188 ASP A CG 1 ATOM 1106 O OD1 . ASP A 1 190 ? 8.204 39.258 -20.419 1.00 40.09 ? 188 ASP A OD1 1 ATOM 1107 O OD2 . ASP A 1 190 ? 6.242 39.301 -21.460 1.00 50.37 ? 188 ASP A OD2 1 ATOM 1108 N N . PHE A 1 191 ? 6.946 41.492 -15.988 1.00 41.77 ? 189 PHE A N 1 ATOM 1109 C CA . PHE A 1 191 ? 7.112 42.664 -15.144 1.00 42.76 ? 189 PHE A CA 1 ATOM 1110 C C . PHE A 1 191 ? 8.637 42.938 -15.072 1.00 46.84 ? 189 PHE A C 1 ATOM 1111 O O . PHE A 1 191 ? 9.056 44.102 -14.983 1.00 48.74 ? 189 PHE A O 1 ATOM 1112 C CB . PHE A 1 191 ? 6.541 42.472 -13.721 1.00 45.71 ? 189 PHE A CB 1 ATOM 1113 C CG . PHE A 1 191 ? 7.236 43.400 -12.731 1.00 50.48 ? 189 PHE A CG 1 ATOM 1114 C CD1 . PHE A 1 191 ? 7.004 44.785 -12.759 1.00 54.36 ? 189 PHE A CD1 1 ATOM 1115 C CD2 . PHE A 1 191 ? 8.219 42.911 -11.856 1.00 53.39 ? 189 PHE A CD2 1 ATOM 1116 C CE1 . PHE A 1 191 ? 7.720 45.649 -11.916 1.00 55.14 ? 189 PHE A CE1 1 ATOM 1117 C CE2 . PHE A 1 191 ? 8.920 43.778 -11.007 1.00 55.29 ? 189 PHE A CE2 1 ATOM 1118 C CZ . PHE A 1 191 ? 8.662 45.137 -11.039 1.00 53.24 ? 189 PHE A CZ 1 ATOM 1119 N N . PHE A 1 192 ? 9.452 41.885 -15.133 1.00 40.36 ? 190 PHE A N 1 ATOM 1120 C CA . PHE A 1 192 ? 10.891 42.074 -15.038 1.00 39.80 ? 190 PHE A CA 1 ATOM 1121 C C . PHE A 1 192 ? 11.469 42.662 -16.293 1.00 43.35 ? 190 PHE A C 1 ATOM 1122 O O . PHE A 1 192 ? 12.160 43.673 -16.192 1.00 43.03 ? 190 PHE A O 1 ATOM 1123 C CB . PHE A 1 192 ? 11.616 40.796 -14.580 1.00 40.71 ? 190 PHE A CB 1 ATOM 1124 C CG . PHE A 1 192 ? 11.140 40.422 -13.196 1.00 40.68 ? 190 PHE A CG 1 ATOM 1125 C CD1 . PHE A 1 192 ? 11.523 41.163 -12.091 1.00 41.99 ? 190 PHE A CD1 1 ATOM 1126 C CD2 . PHE A 1 192 ? 10.214 39.400 -13.014 1.00 43.62 ? 190 PHE A CD2 1 ATOM 1127 C CE1 . PHE A 1 192 ? 11.020 40.870 -10.828 1.00 43.79 ? 190 PHE A CE1 1 ATOM 1128 C CE2 . PHE A 1 192 ? 9.693 39.123 -11.748 1.00 46.19 ? 190 PHE A CE2 1 ATOM 1129 C CZ . PHE A 1 192 ? 10.098 39.863 -10.664 1.00 43.73 ? 190 PHE A CZ 1 ATOM 1130 N N . GLN A 1 193 ? 11.111 42.114 -17.472 1.00 39.84 ? 191 GLN A N 1 ATOM 1131 C CA . GLN A 1 193 ? 11.586 42.601 -18.777 1.00 39.03 ? 191 GLN A CA 1 ATOM 1132 C C . GLN A 1 193 ? 11.095 44.042 -19.040 1.00 41.79 ? 191 GLN A C 1 ATOM 1133 O O . GLN A 1 193 ? 11.837 44.834 -19.598 1.00 40.52 ? 191 GLN A O 1 ATOM 1134 C CB . GLN A 1 193 ? 11.131 41.626 -19.873 1.00 40.46 ? 191 GLN A CB 1 ATOM 1135 C CG . GLN A 1 193 ? 11.463 42.011 -21.328 1.00 48.77 ? 191 GLN A CG 1 ATOM 1136 C CD . GLN A 1 193 ? 11.159 40.902 -22.313 1.00 59.27 ? 191 GLN A CD 1 ATOM 1137 O OE1 . GLN A 1 193 ? 11.657 40.889 -23.428 1.00 59.32 ? 191 GLN A OE1 1 ATOM 1138 N NE2 . GLN A 1 193 ? 10.376 39.909 -21.924 1.00 42.00 ? 191 GLN A NE2 1 ATOM 1139 N N . ALA A 1 194 ? 9.853 44.374 -18.624 1.00 38.49 ? 192 ALA A N 1 ATOM 1140 C CA . ALA A 1 194 ? 9.288 45.715 -18.786 1.00 37.74 ? 192 ALA A CA 1 ATOM 1141 C C . ALA A 1 194 ? 10.057 46.699 -17.919 1.00 43.77 ? 192 ALA A C 1 ATOM 1142 O O . ALA A 1 194 ? 10.350 47.801 -18.387 1.00 44.36 ? 192 ALA A O 1 ATOM 1143 C CB . ALA A 1 194 ? 7.806 45.723 -18.432 1.00 37.77 ? 192 ALA A CB 1 ATOM 1144 N N . LYS A 1 195 ? 10.431 46.292 -16.674 1.00 40.53 ? 193 LYS A N 1 ATOM 1145 C CA . LYS A 1 195 ? 11.250 47.123 -15.789 1.00 40.78 ? 193 LYS A CA 1 ATOM 1146 C C . LYS A 1 195 ? 12.639 47.322 -16.430 1.00 44.44 ? 193 LYS A C 1 ATOM 1147 O O . LYS A 1 195 ? 13.093 48.469 -16.548 1.00 44.32 ? 193 LYS A O 1 ATOM 1148 C CB . LYS A 1 195 ? 11.383 46.489 -14.383 1.00 44.46 ? 193 LYS A CB 1 ATOM 1149 C CG . LYS A 1 195 ? 11.986 47.410 -13.307 1.00 49.15 ? 193 LYS A CG 1 ATOM 1150 C CD . LYS A 1 195 ? 11.933 46.767 -11.939 1.00 63.03 ? 193 LYS A CD 1 ATOM 1151 C CE . LYS A 1 195 ? 12.502 47.673 -10.864 1.00 74.14 ? 193 LYS A CE 1 ATOM 1152 N NZ . LYS A 1 195 ? 12.045 47.275 -9.507 1.00 81.93 ? 193 LYS A NZ 1 ATOM 1153 N N . ALA A 1 196 ? 13.283 46.217 -16.890 1.00 40.90 ? 194 ALA A N 1 ATOM 1154 C CA . ALA A 1 196 ? 14.595 46.270 -17.549 1.00 41.68 ? 194 ALA A CA 1 ATOM 1155 C C . ALA A 1 196 ? 14.636 47.322 -18.684 1.00 49.09 ? 194 ALA A C 1 ATOM 1156 O O . ALA A 1 196 ? 15.611 48.067 -18.777 1.00 50.25 ? 194 ALA A O 1 ATOM 1157 C CB . ALA A 1 196 ? 14.976 44.903 -18.082 1.00 42.11 ? 194 ALA A CB 1 ATOM 1158 N N . MET A 1 197 ? 13.551 47.419 -19.490 1.00 45.44 ? 195 MET A N 1 ATOM 1159 C CA . MET A 1 197 ? 13.395 48.373 -20.588 1.00 45.22 ? 195 MET A CA 1 ATOM 1160 C C . MET A 1 197 ? 13.419 49.820 -20.105 1.00 48.55 ? 195 MET A C 1 ATOM 1161 O O . MET A 1 197 ? 14.210 50.624 -20.603 1.00 46.31 ? 195 MET A O 1 ATOM 1162 C CB . MET A 1 197 ? 12.109 48.073 -21.385 1.00 47.36 ? 195 MET A CB 1 ATOM 1163 C CG . MET A 1 197 ? 12.174 46.753 -22.133 1.00 50.10 ? 195 MET A CG 1 ATOM 1164 S SD . MET A 1 197 ? 10.651 46.353 -22.995 1.00 53.27 ? 195 MET A SD 1 ATOM 1165 C CE . MET A 1 197 ? 11.063 44.820 -23.652 1.00 49.85 ? 195 MET A CE 1 ATOM 1166 N N . ALA A 1 198 ? 12.581 50.128 -19.108 1.00 47.10 ? 196 ALA A N 1 ATOM 1167 C CA . ALA A 1 198 ? 12.503 51.439 -18.454 1.00 47.72 ? 196 ALA A CA 1 ATOM 1168 C C . ALA A 1 198 ? 13.855 51.855 -17.833 1.00 51.40 ? 196 ALA A C 1 ATOM 1169 O O . ALA A 1 198 ? 14.191 53.039 -17.833 1.00 51.80 ? 196 ALA A O 1 ATOM 1170 C CB . ALA A 1 198 ? 11.435 51.412 -17.381 1.00 48.57 ? 196 ALA A CB 1 ATOM 1171 N N . GLU A 1 199 ? 14.617 50.884 -17.314 1.00 46.14 ? 197 GLU A N 1 ATOM 1172 C CA . GLU A 1 199 ? 15.930 51.151 -16.754 1.00 45.58 ? 197 GLU A CA 1 ATOM 1173 C C . GLU A 1 199 ? 16.941 51.463 -17.878 1.00 47.63 ? 197 GLU A C 1 ATOM 1174 O O . GLU A 1 199 ? 17.751 52.389 -17.724 1.00 48.44 ? 197 GLU A O 1 ATOM 1175 C CB . GLU A 1 199 ? 16.372 50.031 -15.790 1.00 47.02 ? 197 GLU A CB 1 ATOM 1176 C CG . GLU A 1 199 ? 15.598 50.056 -14.475 1.00 52.86 ? 197 GLU A CG 1 ATOM 1177 C CD . GLU A 1 199 ? 16.178 49.242 -13.335 1.00 67.36 ? 197 GLU A CD 1 ATOM 1178 O OE1 . GLU A 1 199 ? 17.089 48.423 -13.589 1.00 48.48 ? 197 GLU A OE1 1 ATOM 1179 O OE2 . GLU A 1 199 ? 15.720 49.418 -12.181 1.00 66.97 ? 197 GLU A OE2 1 ATOM 1180 N N . ILE A 1 200 ? 16.827 50.783 -19.045 1.00 41.85 ? 198 ILE A N 1 ATOM 1181 C CA . ILE A 1 200 ? 17.667 51.104 -20.227 1.00 39.97 ? 198 ILE A CA 1 ATOM 1182 C C . ILE A 1 200 ? 17.393 52.567 -20.658 1.00 43.32 ? 198 ILE A C 1 ATOM 1183 O O . ILE A 1 200 ? 18.346 53.317 -20.818 1.00 43.53 ? 198 ILE A O 1 ATOM 1184 C CB . ILE A 1 200 ? 17.544 50.121 -21.425 1.00 41.27 ? 198 ILE A CB 1 ATOM 1185 C CG1 . ILE A 1 200 ? 17.898 48.693 -21.021 1.00 41.01 ? 198 ILE A CG1 1 ATOM 1186 C CG2 . ILE A 1 200 ? 18.419 50.572 -22.600 1.00 41.45 ? 198 ILE A CG2 1 ATOM 1187 C CD1 . ILE A 1 200 ? 17.632 47.649 -22.070 1.00 41.08 ? 198 ILE A CD1 1 ATOM 1188 N N . LEU A 1 201 ? 16.114 52.983 -20.755 1.00 38.78 ? 199 LEU A N 1 ATOM 1189 C CA . LEU A 1 201 ? 15.766 54.346 -21.157 1.00 38.77 ? 199 LEU A CA 1 ATOM 1190 C C . LEU A 1 201 ? 16.471 55.345 -20.289 1.00 46.36 ? 199 LEU A C 1 ATOM 1191 O O . LEU A 1 201 ? 17.316 56.106 -20.788 1.00 46.01 ? 199 LEU A O 1 ATOM 1192 C CB . LEU A 1 201 ? 14.247 54.617 -21.148 1.00 38.10 ? 199 LEU A CB 1 ATOM 1193 C CG . LEU A 1 201 ? 13.337 53.851 -22.124 1.00 42.20 ? 199 LEU A CG 1 ATOM 1194 C CD1 . LEU A 1 201 ? 12.084 54.618 -22.406 1.00 40.74 ? 199 LEU A CD1 1 ATOM 1195 C CD2 . LEU A 1 201 ? 14.040 53.445 -23.438 1.00 44.92 ? 199 LEU A CD2 1 ATOM 1196 N N . ARG A 1 202 ? 16.182 55.267 -18.971 1.00 45.75 ? 200 ARG A N 1 ATOM 1197 C CA . ARG A 1 202 ? 16.722 56.091 -17.879 1.00 46.18 ? 200 ARG A CA 1 ATOM 1198 C C . ARG A 1 202 ? 18.235 56.227 -17.955 1.00 49.74 ? 200 ARG A C 1 ATOM 1199 O O . ARG A 1 202 ? 18.741 57.350 -17.968 1.00 49.12 ? 200 ARG A O 1 ATOM 1200 C CB . ARG A 1 202 ? 16.273 55.528 -16.501 1.00 46.91 ? 200 ARG A CB 1 ATOM 1201 C CG . ARG A 1 202 ? 16.303 56.516 -15.324 1.00 48.18 ? 200 ARG A CG 1 ATOM 1202 C CD . ARG A 1 202 ? 15.501 57.787 -15.574 1.00 53.71 ? 200 ARG A CD 1 ATOM 1203 N NE . ARG A 1 202 ? 16.290 58.819 -16.263 1.00 53.71 ? 200 ARG A NE 1 ATOM 1204 C CZ . ARG A 1 202 ? 15.931 60.099 -16.383 1.00 63.87 ? 200 ARG A CZ 1 ATOM 1205 N NH1 . ARG A 1 202 ? 14.776 60.528 -15.870 1.00 32.81 ? 200 ARG A NH1 1 ATOM 1206 N NH2 . ARG A 1 202 ? 16.714 60.956 -17.030 1.00 54.09 ? 200 ARG A NH2 1 ATOM 1207 N N . PHE A 1 203 ? 18.946 55.090 -18.092 1.00 47.05 ? 201 PHE A N 1 ATOM 1208 C CA . PHE A 1 203 ? 20.403 55.072 -18.214 1.00 47.50 ? 201 PHE A CA 1 ATOM 1209 C C . PHE A 1 203 ? 20.891 56.001 -19.295 1.00 51.10 ? 201 PHE A C 1 ATOM 1210 O O . PHE A 1 203 ? 21.948 56.601 -19.125 1.00 51.46 ? 201 PHE A O 1 ATOM 1211 C CB . PHE A 1 203 ? 20.918 53.655 -18.498 1.00 49.94 ? 201 PHE A CB 1 ATOM 1212 C CG . PHE A 1 203 ? 22.425 53.552 -18.564 1.00 52.31 ? 201 PHE A CG 1 ATOM 1213 C CD1 . PHE A 1 203 ? 23.173 53.283 -17.419 1.00 54.40 ? 201 PHE A CD1 1 ATOM 1214 C CD2 . PHE A 1 203 ? 23.102 53.719 -19.774 1.00 55.45 ? 201 PHE A CD2 1 ATOM 1215 C CE1 . PHE A 1 203 ? 24.573 53.206 -17.481 1.00 56.54 ? 201 PHE A CE1 1 ATOM 1216 C CE2 . PHE A 1 203 ? 24.500 53.664 -19.827 1.00 55.70 ? 201 PHE A CE2 1 ATOM 1217 C CZ . PHE A 1 203 ? 25.223 53.400 -18.682 1.00 54.34 ? 201 PHE A CZ 1 ATOM 1218 N N . PHE A 1 204 ? 20.165 56.062 -20.430 1.00 47.45 ? 202 PHE A N 1 ATOM 1219 C CA . PHE A 1 204 ? 20.552 56.870 -21.595 1.00 46.97 ? 202 PHE A CA 1 ATOM 1220 C C . PHE A 1 204 ? 19.831 58.210 -21.628 1.00 56.35 ? 202 PHE A C 1 ATOM 1221 O O . PHE A 1 204 ? 20.022 59.007 -22.551 1.00 56.90 ? 202 PHE A O 1 ATOM 1222 C CB . PHE A 1 204 ? 20.385 56.089 -22.910 1.00 46.11 ? 202 PHE A CB 1 ATOM 1223 C CG . PHE A 1 204 ? 21.300 54.901 -23.048 1.00 45.53 ? 202 PHE A CG 1 ATOM 1224 C CD1 . PHE A 1 204 ? 22.660 55.073 -23.266 1.00 47.96 ? 202 PHE A CD1 1 ATOM 1225 C CD2 . PHE A 1 204 ? 20.801 53.608 -22.969 1.00 46.37 ? 202 PHE A CD2 1 ATOM 1226 C CE1 . PHE A 1 204 ? 23.512 53.971 -23.377 1.00 48.87 ? 202 PHE A CE1 1 ATOM 1227 C CE2 . PHE A 1 204 ? 21.643 52.507 -23.106 1.00 49.45 ? 202 PHE A CE2 1 ATOM 1228 C CZ . PHE A 1 204 ? 22.996 52.690 -23.311 1.00 47.80 ? 202 PHE A CZ 1 ATOM 1229 N N . ASN A 1 205 ? 19.021 58.460 -20.596 1.00 54.82 ? 203 ASN A N 1 ATOM 1230 C CA . ASN A 1 205 ? 18.266 59.691 -20.401 1.00 55.17 ? 203 ASN A CA 1 ATOM 1231 C C . ASN A 1 205 ? 17.207 59.922 -21.487 1.00 57.41 ? 203 ASN A C 1 ATOM 1232 O O . ASN A 1 205 ? 16.950 61.082 -21.833 1.00 57.76 ? 203 ASN A O 1 ATOM 1233 C CB . ASN A 1 205 ? 19.223 60.893 -20.225 1.00 58.74 ? 203 ASN A CB 1 ATOM 1234 C CG . ASN A 1 205 ? 20.031 60.824 -18.939 1.00 82.22 ? 203 ASN A CG 1 ATOM 1235 O OD1 . ASN A 1 205 ? 19.464 60.582 -17.859 1.00 69.48 ? 203 ASN A OD1 1 ATOM 1236 N ND2 . ASN A 1 205 ? 21.366 61.038 -19.036 1.00 80.64 ? 203 ASN A ND2 1 ATOM 1237 N N . TRP A 1 206 ? 16.531 58.813 -21.959 1.00 50.64 ? 204 TRP A N 1 ATOM 1238 C CA . TRP A 1 206 ? 15.454 58.863 -22.978 1.00 48.48 ? 204 TRP A CA 1 ATOM 1239 C C . TRP A 1 206 ? 14.083 59.061 -22.284 1.00 52.70 ? 204 TRP A C 1 ATOM 1240 O O . TRP A 1 206 ? 13.372 58.095 -21.965 1.00 53.13 ? 204 TRP A O 1 ATOM 1241 C CB . TRP A 1 206 ? 15.497 57.627 -23.914 1.00 45.74 ? 204 TRP A CB 1 ATOM 1242 C CG . TRP A 1 206 ? 16.795 57.435 -24.661 1.00 45.10 ? 204 TRP A CG 1 ATOM 1243 C CD1 . TRP A 1 206 ? 17.662 58.408 -25.060 1.00 47.52 ? 204 TRP A CD1 1 ATOM 1244 C CD2 . TRP A 1 206 ? 17.341 56.194 -25.135 1.00 44.23 ? 204 TRP A CD2 1 ATOM 1245 N NE1 . TRP A 1 206 ? 18.747 57.844 -25.691 1.00 46.20 ? 204 TRP A NE1 1 ATOM 1246 C CE2 . TRP A 1 206 ? 18.551 56.495 -25.799 1.00 47.32 ? 204 TRP A CE2 1 ATOM 1247 C CE3 . TRP A 1 206 ? 16.951 54.847 -25.021 1.00 45.27 ? 204 TRP A CE3 1 ATOM 1248 C CZ2 . TRP A 1 206 ? 19.367 55.501 -26.361 1.00 46.50 ? 204 TRP A CZ2 1 ATOM 1249 C CZ3 . TRP A 1 206 ? 17.756 53.862 -25.586 1.00 46.15 ? 204 TRP A CZ3 1 ATOM 1250 C CH2 . TRP A 1 206 ? 18.941 54.193 -26.258 1.00 46.47 ? 204 TRP A CH2 1 ATOM 1251 N N . THR A 1 207 ? 13.735 60.338 -22.028 1.00 47.15 ? 205 THR A N 1 ATOM 1252 C CA . THR A 1 207 ? 12.565 60.726 -21.239 1.00 45.30 ? 205 THR A CA 1 ATOM 1253 C C . THR A 1 207 ? 11.305 61.079 -22.057 1.00 47.56 ? 205 THR A C 1 ATOM 1254 O O . THR A 1 207 ? 10.247 61.354 -21.457 1.00 47.73 ? 205 THR A O 1 ATOM 1255 C CB . THR A 1 207 ? 12.976 61.857 -20.304 1.00 54.19 ? 205 THR A CB 1 ATOM 1256 O OG1 . THR A 1 207 ? 13.390 62.963 -21.108 1.00 57.61 ? 205 THR A OG1 1 ATOM 1257 C CG2 . THR A 1 207 ? 14.121 61.446 -19.357 1.00 50.40 ? 205 THR A CG2 1 ATOM 1258 N N . TYR A 1 208 ? 11.396 61.065 -23.407 1.00 42.21 ? 206 TYR A N 1 ATOM 1259 C CA . TYR A 1 208 ? 10.238 61.310 -24.293 1.00 41.53 ? 206 TYR A CA 1 ATOM 1260 C C . TYR A 1 208 ? 10.213 60.214 -25.352 1.00 45.62 ? 206 TYR A C 1 ATOM 1261 O O . TYR A 1 208 ? 11.001 60.232 -26.299 1.00 45.56 ? 206 TYR A O 1 ATOM 1262 C CB . TYR A 1 208 ? 10.212 62.742 -24.872 1.00 42.13 ? 206 TYR A CB 1 ATOM 1263 C CG . TYR A 1 208 ? 8.902 63.133 -25.523 1.00 44.36 ? 206 TYR A CG 1 ATOM 1264 C CD1 . TYR A 1 208 ? 7.752 63.343 -24.760 1.00 46.07 ? 206 TYR A CD1 1 ATOM 1265 C CD2 . TYR A 1 208 ? 8.821 63.351 -26.898 1.00 45.48 ? 206 TYR A CD2 1 ATOM 1266 C CE1 . TYR A 1 208 ? 6.535 63.685 -25.360 1.00 45.32 ? 206 TYR A CE1 1 ATOM 1267 C CE2 . TYR A 1 208 ? 7.613 63.725 -27.506 1.00 46.10 ? 206 TYR A CE2 1 ATOM 1268 C CZ . TYR A 1 208 ? 6.473 63.889 -26.733 1.00 51.79 ? 206 TYR A CZ 1 ATOM 1269 O OH . TYR A 1 208 ? 5.277 64.237 -27.334 1.00 53.68 ? 206 TYR A OH 1 ATOM 1270 N N . VAL A 1 209 ? 9.394 59.182 -25.114 1.00 42.40 ? 207 VAL A N 1 ATOM 1271 C CA . VAL A 1 209 ? 9.352 58.020 -25.997 1.00 42.31 ? 207 VAL A CA 1 ATOM 1272 C C . VAL A 1 209 ? 7.953 57.646 -26.495 1.00 47.83 ? 207 VAL A C 1 ATOM 1273 O O . VAL A 1 209 ? 6.960 58.195 -26.043 1.00 47.05 ? 207 VAL A O 1 ATOM 1274 C CB . VAL A 1 209 ? 10.045 56.803 -25.359 1.00 44.96 ? 207 VAL A CB 1 ATOM 1275 C CG1 . VAL A 1 209 ? 11.449 57.153 -24.886 1.00 45.15 ? 207 VAL A CG1 1 ATOM 1276 C CG2 . VAL A 1 209 ? 9.206 56.214 -24.229 1.00 44.33 ? 207 VAL A CG2 1 ATOM 1277 N N . SER A 1 210 ? 7.908 56.675 -27.426 1.00 45.69 ? 208 SER A N 1 ATOM 1278 C CA . SER A 1 210 ? 6.698 56.081 -27.969 1.00 45.31 ? 208 SER A CA 1 ATOM 1279 C C . SER A 1 210 ? 6.754 54.538 -27.825 1.00 47.62 ? 208 SER A C 1 ATOM 1280 O O . SER A 1 210 ? 7.834 53.933 -27.789 1.00 45.66 ? 208 SER A O 1 ATOM 1281 C CB . SER A 1 210 ? 6.521 56.484 -29.421 1.00 50.30 ? 208 SER A CB 1 ATOM 1282 O OG . SER A 1 210 ? 6.126 57.842 -29.479 1.00 65.94 ? 208 SER A OG 1 ATOM 1283 N N . THR A 1 211 ? 5.573 53.917 -27.710 1.00 43.16 ? 209 THR A N 1 ATOM 1284 C CA . THR A 1 211 ? 5.434 52.475 -27.554 1.00 40.96 ? 209 THR A CA 1 ATOM 1285 C C . THR A 1 211 ? 4.602 51.877 -28.687 1.00 40.13 ? 209 THR A C 1 ATOM 1286 O O . THR A 1 211 ? 3.766 52.557 -29.284 1.00 36.26 ? 209 THR A O 1 ATOM 1287 C CB . THR A 1 211 ? 4.780 52.136 -26.209 1.00 44.41 ? 209 THR A CB 1 ATOM 1288 O OG1 . THR A 1 211 ? 3.423 52.576 -26.229 1.00 44.27 ? 209 THR A OG1 1 ATOM 1289 C CG2 . THR A 1 211 ? 5.513 52.733 -25.012 1.00 38.11 ? 209 THR A CG2 1 ATOM 1290 N N . VAL A 1 212 ? 4.852 50.585 -28.967 1.00 37.08 ? 210 VAL A N 1 ATOM 1291 C CA . VAL A 1 212 ? 4.130 49.759 -29.946 1.00 36.86 ? 210 VAL A CA 1 ATOM 1292 C C . VAL A 1 212 ? 3.974 48.392 -29.292 1.00 40.71 ? 210 VAL A C 1 ATOM 1293 O O . VAL A 1 212 ? 4.929 47.841 -28.742 1.00 39.85 ? 210 VAL A O 1 ATOM 1294 C CB . VAL A 1 212 ? 4.776 49.643 -31.369 1.00 40.26 ? 210 VAL A CB 1 ATOM 1295 C CG1 . VAL A 1 212 ? 3.838 48.933 -32.325 1.00 39.92 ? 210 VAL A CG1 1 ATOM 1296 C CG2 . VAL A 1 212 ? 5.181 50.999 -31.947 1.00 39.36 ? 210 VAL A CG2 1 ATOM 1297 N N . ALA A 1 213 ? 2.746 47.899 -29.263 1.00 39.26 ? 211 ALA A N 1 ATOM 1298 C CA . ALA A 1 213 ? 2.409 46.583 -28.702 1.00 38.64 ? 211 ALA A CA 1 ATOM 1299 C C . ALA A 1 213 ? 1.610 45.811 -29.732 1.00 39.05 ? 211 ALA A C 1 ATOM 1300 O O . ALA A 1 213 ? 0.850 46.416 -30.485 1.00 35.09 ? 211 ALA A O 1 ATOM 1301 C CB . ALA A 1 213 ? 1.582 46.737 -27.438 1.00 39.17 ? 211 ALA A CB 1 ATOM 1302 N N . SER A 1 214 ? 1.816 44.479 -29.782 1.00 36.82 ? 212 SER A N 1 ATOM 1303 C CA . SER A 1 214 ? 1.081 43.536 -30.629 1.00 35.50 ? 212 SER A CA 1 ATOM 1304 C C . SER A 1 214 ? -0.192 43.243 -29.836 1.00 42.31 ? 212 SER A C 1 ATOM 1305 O O . SER A 1 214 ? -0.127 43.099 -28.606 1.00 43.10 ? 212 SER A O 1 ATOM 1306 C CB . SER A 1 214 ? 1.854 42.225 -30.760 1.00 37.27 ? 212 SER A CB 1 ATOM 1307 O OG . SER A 1 214 ? 3.121 42.300 -31.396 1.00 37.99 ? 212 SER A OG 1 ATOM 1308 N N . GLU A 1 215 ? -1.346 43.178 -30.511 1.00 40.86 ? 213 GLU A N 1 ATOM 1309 C CA . GLU A 1 215 ? -2.626 42.828 -29.892 1.00 41.26 ? 213 GLU A CA 1 ATOM 1310 C C . GLU A 1 215 ? -2.394 41.439 -29.265 1.00 46.70 ? 213 GLU A C 1 ATOM 1311 O O . GLU A 1 215 ? -1.757 40.575 -29.915 1.00 48.26 ? 213 GLU A O 1 ATOM 1312 C CB . GLU A 1 215 ? -3.696 42.716 -30.990 1.00 42.86 ? 213 GLU A CB 1 ATOM 1313 C CG . GLU A 1 215 ? -5.111 43.053 -30.532 1.00 65.28 ? 213 GLU A CG 1 ATOM 1314 C CD . GLU A 1 215 ? -6.206 42.980 -31.589 1.00 102.41 ? 213 GLU A CD 1 ATOM 1315 O OE1 . GLU A 1 215 ? -7.178 42.216 -31.383 1.00 95.94 ? 213 GLU A OE1 1 ATOM 1316 O OE2 . GLU A 1 215 ? -6.108 43.699 -32.611 1.00 104.95 ? 213 GLU A OE2 1 ATOM 1317 N N . GLY A 1 216 ? -2.836 41.258 -28.017 1.00 38.82 ? 214 GLY A N 1 ATOM 1318 C CA . GLY A 1 216 ? -2.695 39.991 -27.319 1.00 37.29 ? 214 GLY A CA 1 ATOM 1319 C C . GLY A 1 216 ? -2.278 40.134 -25.873 1.00 41.88 ? 214 GLY A C 1 ATOM 1320 O O . GLY A 1 216 ? -2.093 41.246 -25.376 1.00 42.26 ? 214 GLY A O 1 ATOM 1321 N N . ASP A 1 217 ? -2.086 39.001 -25.202 1.00 38.36 ? 215 ASP A N 1 ATOM 1322 C CA . ASP A 1 217 ? -1.709 38.930 -23.797 1.00 38.88 ? 215 ASP A CA 1 ATOM 1323 C C . ASP A 1 217 ? -0.246 39.197 -23.545 1.00 42.37 ? 215 ASP A C 1 ATOM 1324 O O . ASP A 1 217 ? 0.135 39.489 -22.414 1.00 42.47 ? 215 ASP A O 1 ATOM 1325 C CB . ASP A 1 217 ? -2.106 37.573 -23.206 1.00 41.96 ? 215 ASP A CB 1 ATOM 1326 C CG . ASP A 1 217 ? -3.599 37.338 -23.153 1.00 62.86 ? 215 ASP A CG 1 ATOM 1327 O OD1 . ASP A 1 217 ? -4.319 38.212 -22.608 1.00 67.10 ? 215 ASP A OD1 1 ATOM 1328 O OD2 . ASP A 1 217 ? -4.051 36.273 -23.644 1.00 68.79 ? 215 ASP A OD2 1 ATOM 1329 N N . TYR A 1 218 ? 0.585 39.083 -24.575 1.00 38.46 ? 216 TYR A N 1 ATOM 1330 C CA . TYR A 1 218 ? 2.005 39.347 -24.441 1.00 37.30 ? 216 TYR A CA 1 ATOM 1331 C C . TYR A 1 218 ? 2.283 40.860 -24.648 1.00 42.61 ? 216 TYR A C 1 ATOM 1332 O O . TYR A 1 218 ? 2.857 41.524 -23.777 1.00 42.49 ? 216 TYR A O 1 ATOM 1333 C CB . TYR A 1 218 ? 2.794 38.451 -25.410 1.00 37.06 ? 216 TYR A CB 1 ATOM 1334 C CG . TYR A 1 218 ? 4.236 38.860 -25.609 1.00 38.22 ? 216 TYR A CG 1 ATOM 1335 C CD1 . TYR A 1 218 ? 5.179 38.679 -24.600 1.00 41.10 ? 216 TYR A CD1 1 ATOM 1336 C CD2 . TYR A 1 218 ? 4.665 39.414 -26.812 1.00 37.29 ? 216 TYR A CD2 1 ATOM 1337 C CE1 . TYR A 1 218 ? 6.509 39.062 -24.774 1.00 42.04 ? 216 TYR A CE1 1 ATOM 1338 C CE2 . TYR A 1 218 ? 5.983 39.830 -26.984 1.00 37.97 ? 216 TYR A CE2 1 ATOM 1339 C CZ . TYR A 1 218 ? 6.906 39.633 -25.968 1.00 45.49 ? 216 TYR A CZ 1 ATOM 1340 O OH . TYR A 1 218 ? 8.220 39.977 -26.138 1.00 45.91 ? 216 TYR A OH 1 ATOM 1341 N N . GLY A 1 219 ? 1.854 41.382 -25.789 1.00 39.40 ? 217 GLY A N 1 ATOM 1342 C CA . GLY A 1 219 ? 2.117 42.758 -26.172 1.00 39.32 ? 217 GLY A CA 1 ATOM 1343 C C . GLY A 1 219 ? 1.516 43.790 -25.264 1.00 42.48 ? 217 GLY A C 1 ATOM 1344 O O . GLY A 1 219 ? 2.236 44.610 -24.696 1.00 41.06 ? 217 GLY A O 1 ATOM 1345 N N . GLU A 1 220 ? 0.185 43.727 -25.129 1.00 40.38 ? 218 GLU A N 1 ATOM 1346 C CA . GLU A 1 220 ? -0.636 44.656 -24.355 1.00 39.86 ? 218 GLU A CA 1 ATOM 1347 C C . GLU A 1 220 ? -0.274 44.705 -22.851 1.00 43.63 ? 218 GLU A C 1 ATOM 1348 O O . GLU A 1 220 ? -0.096 45.816 -22.317 1.00 44.08 ? 218 GLU A O 1 ATOM 1349 C CB . GLU A 1 220 ? -2.121 44.376 -24.581 1.00 40.74 ? 218 GLU A CB 1 ATOM 1350 C CG . GLU A 1 220 ? -2.578 44.646 -26.009 1.00 53.00 ? 218 GLU A CG 1 ATOM 1351 C CD . GLU A 1 220 ? -4.055 44.399 -26.280 1.00 76.24 ? 218 GLU A CD 1 ATOM 1352 O OE1 . GLU A 1 220 ? -4.896 45.159 -25.743 1.00 63.10 ? 218 GLU A OE1 1 ATOM 1353 O OE2 . GLU A 1 220 ? -4.371 43.453 -27.039 1.00 65.12 ? 218 GLU A OE2 1 ATOM 1354 N N . THR A 1 221 ? -0.114 43.535 -22.187 1.00 37.43 ? 219 THR A N 1 ATOM 1355 C CA . THR A 1 221 ? 0.245 43.545 -20.765 1.00 38.30 ? 219 THR A CA 1 ATOM 1356 C C . THR A 1 221 ? 1.739 44.011 -20.535 1.00 44.26 ? 219 THR A C 1 ATOM 1357 O O . THR A 1 221 ? 2.031 44.698 -19.530 1.00 45.00 ? 219 THR A O 1 ATOM 1358 C CB . THR A 1 221 ? -0.097 42.196 -20.102 1.00 52.07 ? 219 THR A CB 1 ATOM 1359 O OG1 . THR A 1 221 ? 0.842 41.203 -20.497 1.00 53.32 ? 219 THR A OG1 1 ATOM 1360 C CG2 . THR A 1 221 ? -1.492 41.720 -20.434 1.00 53.33 ? 219 THR A CG2 1 ATOM 1361 N N . GLY A 1 222 ? 2.635 43.631 -21.470 1.00 37.89 ? 220 GLY A N 1 ATOM 1362 C CA . GLY A 1 222 ? 4.038 44.009 -21.472 1.00 36.68 ? 220 GLY A CA 1 ATOM 1363 C C . GLY A 1 222 ? 4.207 45.517 -21.525 1.00 41.90 ? 220 GLY A C 1 ATOM 1364 O O . GLY A 1 222 ? 4.981 46.085 -20.753 1.00 42.34 ? 220 GLY A O 1 ATOM 1365 N N . ILE A 1 223 ? 3.464 46.192 -22.408 1.00 38.57 ? 221 ILE A N 1 ATOM 1366 C CA . ILE A 1 223 ? 3.553 47.657 -22.535 1.00 37.56 ? 221 ILE A CA 1 ATOM 1367 C C . ILE A 1 223 ? 2.912 48.351 -21.353 1.00 42.24 ? 221 ILE A C 1 ATOM 1368 O O . ILE A 1 223 ? 3.383 49.405 -20.979 1.00 43.37 ? 221 ILE A O 1 ATOM 1369 C CB . ILE A 1 223 ? 3.035 48.183 -23.919 1.00 39.00 ? 221 ILE A CB 1 ATOM 1370 C CG1 . ILE A 1 223 ? 4.127 48.063 -25.011 1.00 38.91 ? 221 ILE A CG1 1 ATOM 1371 C CG2 . ILE A 1 223 ? 2.554 49.595 -23.856 1.00 38.04 ? 221 ILE A CG2 1 ATOM 1372 C CD1 . ILE A 1 223 ? 5.551 48.754 -24.754 1.00 35.86 ? 221 ILE A CD1 1 ATOM 1373 N N . GLU A 1 224 ? 1.859 47.772 -20.767 1.00 39.94 ? 222 GLU A N 1 ATOM 1374 C CA . GLU A 1 224 ? 1.154 48.325 -19.601 1.00 39.83 ? 222 GLU A CA 1 ATOM 1375 C C . GLU A 1 224 ? 2.128 48.464 -18.460 1.00 40.81 ? 222 GLU A C 1 ATOM 1376 O O . GLU A 1 224 ? 2.314 49.558 -17.948 1.00 41.67 ? 222 GLU A O 1 ATOM 1377 C CB . GLU A 1 224 ? -0.016 47.428 -19.211 1.00 41.73 ? 222 GLU A CB 1 ATOM 1378 C CG . GLU A 1 224 ? -1.178 48.204 -18.633 1.00 60.04 ? 222 GLU A CG 1 ATOM 1379 C CD . GLU A 1 224 ? -2.393 47.373 -18.258 1.00 89.25 ? 222 GLU A CD 1 ATOM 1380 O OE1 . GLU A 1 224 ? -3.525 47.912 -18.332 1.00 92.80 ? 222 GLU A OE1 1 ATOM 1381 O OE2 . GLU A 1 224 ? -2.211 46.194 -17.864 1.00 70.38 ? 222 GLU A OE2 1 ATOM 1382 N N . ALA A 1 225 ? 2.834 47.380 -18.159 1.00 36.05 ? 223 ALA A N 1 ATOM 1383 C CA . ALA A 1 225 ? 3.887 47.298 -17.167 1.00 35.53 ? 223 ALA A CA 1 ATOM 1384 C C . ALA A 1 225 ? 4.979 48.275 -17.510 1.00 43.24 ? 223 ALA A C 1 ATOM 1385 O O . ALA A 1 225 ? 5.378 49.053 -16.646 1.00 45.20 ? 223 ALA A O 1 ATOM 1386 C CB . ALA A 1 225 ? 4.448 45.887 -17.139 1.00 36.14 ? 223 ALA A CB 1 ATOM 1387 N N . PHE A 1 226 ? 5.441 48.268 -18.776 1.00 42.21 ? 224 PHE A N 1 ATOM 1388 C CA . PHE A 1 226 ? 6.484 49.171 -19.264 1.00 43.18 ? 224 PHE A CA 1 ATOM 1389 C C . PHE A 1 226 ? 6.164 50.617 -18.924 1.00 49.14 ? 224 PHE A C 1 ATOM 1390 O O . PHE A 1 226 ? 6.975 51.284 -18.256 1.00 49.95 ? 224 PHE A O 1 ATOM 1391 C CB . PHE A 1 226 ? 6.741 49.045 -20.803 1.00 44.64 ? 224 PHE A CB 1 ATOM 1392 C CG . PHE A 1 226 ? 7.664 50.157 -21.262 1.00 44.59 ? 224 PHE A CG 1 ATOM 1393 C CD1 . PHE A 1 226 ? 9.025 50.125 -20.950 1.00 46.68 ? 224 PHE A CD1 1 ATOM 1394 C CD2 . PHE A 1 226 ? 7.148 51.308 -21.852 1.00 44.45 ? 224 PHE A CD2 1 ATOM 1395 C CE1 . PHE A 1 226 ? 9.858 51.199 -21.269 1.00 47.54 ? 224 PHE A CE1 1 ATOM 1396 C CE2 . PHE A 1 226 ? 7.973 52.389 -22.146 1.00 47.41 ? 224 PHE A CE2 1 ATOM 1397 C CZ . PHE A 1 226 ? 9.326 52.325 -21.865 1.00 46.22 ? 224 PHE A CZ 1 ATOM 1398 N N . GLU A 1 227 ? 4.995 51.087 -19.406 1.00 45.15 ? 225 GLU A N 1 ATOM 1399 C CA . GLU A 1 227 ? 4.518 52.460 -19.270 1.00 45.99 ? 225 GLU A CA 1 ATOM 1400 C C . GLU A 1 227 ? 4.498 52.932 -17.829 1.00 52.16 ? 225 GLU A C 1 ATOM 1401 O O . GLU A 1 227 ? 4.904 54.073 -17.580 1.00 52.85 ? 225 GLU A O 1 ATOM 1402 C CB . GLU A 1 227 ? 3.173 52.666 -19.976 1.00 47.18 ? 225 GLU A CB 1 ATOM 1403 C CG . GLU A 1 227 ? 3.329 52.955 -21.461 1.00 52.60 ? 225 GLU A CG 1 ATOM 1404 C CD . GLU A 1 227 ? 2.081 52.908 -22.334 1.00 74.74 ? 225 GLU A CD 1 ATOM 1405 O OE1 . GLU A 1 227 ? 0.954 52.915 -21.781 1.00 73.81 ? 225 GLU A OE1 1 ATOM 1406 O OE2 . GLU A 1 227 ? 2.237 52.883 -23.582 1.00 49.07 ? 225 GLU A OE2 1 ATOM 1407 N N . LEU A 1 228 ? 4.142 52.038 -16.875 1.00 48.71 ? 226 LEU A N 1 ATOM 1408 C CA . LEU A 1 228 ? 4.152 52.353 -15.429 1.00 47.94 ? 226 LEU A CA 1 ATOM 1409 C C . LEU A 1 228 ? 5.571 52.520 -14.926 1.00 51.19 ? 226 LEU A C 1 ATOM 1410 O O . LEU A 1 228 ? 5.908 53.570 -14.392 1.00 51.32 ? 226 LEU A O 1 ATOM 1411 C CB . LEU A 1 228 ? 3.381 51.302 -14.599 1.00 47.77 ? 226 LEU A CB 1 ATOM 1412 C CG . LEU A 1 228 ? 1.855 51.193 -14.878 1.00 50.97 ? 226 LEU A CG 1 ATOM 1413 C CD1 . LEU A 1 228 ? 1.232 50.105 -14.064 1.00 49.56 ? 226 LEU A CD1 1 ATOM 1414 C CD2 . LEU A 1 228 ? 1.133 52.510 -14.608 1.00 53.34 ? 226 LEU A CD2 1 ATOM 1415 N N . GLU A 1 229 ? 6.438 51.536 -15.185 1.00 48.10 ? 227 GLU A N 1 ATOM 1416 C CA . GLU A 1 229 ? 7.861 51.630 -14.811 1.00 46.70 ? 227 GLU A CA 1 ATOM 1417 C C . GLU A 1 229 ? 8.522 52.890 -15.390 1.00 49.55 ? 227 GLU A C 1 ATOM 1418 O O . GLU A 1 229 ? 9.295 53.558 -14.713 1.00 47.55 ? 227 GLU A O 1 ATOM 1419 C CB . GLU A 1 229 ? 8.617 50.342 -15.192 1.00 47.07 ? 227 GLU A CB 1 ATOM 1420 C CG . GLU A 1 229 ? 8.209 49.137 -14.369 1.00 51.32 ? 227 GLU A CG 1 ATOM 1421 C CD . GLU A 1 229 ? 8.046 49.372 -12.875 1.00 68.13 ? 227 GLU A CD 1 ATOM 1422 O OE1 . GLU A 1 229 ? 6.969 49.011 -12.348 1.00 56.73 ? 227 GLU A OE1 1 ATOM 1423 O OE2 . GLU A 1 229 ? 8.953 49.973 -12.246 1.00 59.71 ? 227 GLU A OE2 1 ATOM 1424 N N . ALA A 1 230 ? 8.152 53.234 -16.623 1.00 48.76 ? 228 ALA A N 1 ATOM 1425 C CA . ALA A 1 230 ? 8.603 54.428 -17.332 1.00 49.79 ? 228 ALA A CA 1 ATOM 1426 C C . ALA A 1 230 ? 8.174 55.728 -16.579 1.00 53.86 ? 228 ALA A C 1 ATOM 1427 O O . ALA A 1 230 ? 9.032 56.534 -16.241 1.00 51.71 ? 228 ALA A O 1 ATOM 1428 C CB . ALA A 1 230 ? 8.052 54.419 -18.759 1.00 50.28 ? 228 ALA A CB 1 ATOM 1429 N N . ARG A 1 231 ? 6.860 55.881 -16.294 1.00 53.14 ? 229 ARG A N 1 ATOM 1430 C CA . ARG A 1 231 ? 6.224 57.011 -15.605 1.00 54.11 ? 229 ARG A CA 1 ATOM 1431 C C . ARG A 1 231 ? 6.975 57.338 -14.297 1.00 59.43 ? 229 ARG A C 1 ATOM 1432 O O . ARG A 1 231 ? 7.411 58.480 -14.094 1.00 59.49 ? 229 ARG A O 1 ATOM 1433 C CB . ARG A 1 231 ? 4.753 56.660 -15.310 1.00 56.21 ? 229 ARG A CB 1 ATOM 1434 C CG . ARG A 1 231 ? 3.819 57.876 -15.211 1.00 71.93 ? 229 ARG A CG 1 ATOM 1435 C CD . ARG A 1 231 ? 2.408 57.553 -14.705 1.00 80.99 ? 229 ARG A CD 1 ATOM 1436 N NE . ARG A 1 231 ? 1.700 56.558 -15.523 1.00 94.05 ? 229 ARG A NE 1 ATOM 1437 C CZ . ARG A 1 231 ? 0.410 56.242 -15.394 1.00 110.65 ? 229 ARG A CZ 1 ATOM 1438 N NH1 . ARG A 1 231 ? -0.351 56.866 -14.500 1.00 93.80 ? 229 ARG A NH1 1 ATOM 1439 N NH2 . ARG A 1 231 ? -0.133 55.315 -16.174 1.00 97.93 ? 229 ARG A NH2 1 ATOM 1440 N N . ALA A 1 232 ? 7.185 56.298 -13.458 1.00 54.78 ? 230 ALA A N 1 ATOM 1441 C CA . ALA A 1 232 ? 7.904 56.334 -12.182 1.00 53.60 ? 230 ALA A CA 1 ATOM 1442 C C . ALA A 1 232 ? 9.334 56.865 -12.312 1.00 57.55 ? 230 ALA A C 1 ATOM 1443 O O . ALA A 1 232 ? 9.871 57.419 -11.342 1.00 57.25 ? 230 ALA A O 1 ATOM 1444 C CB . ALA A 1 232 ? 7.946 54.945 -11.591 1.00 53.82 ? 230 ALA A CB 1 ATOM 1445 N N . ARG A 1 233 ? 9.958 56.659 -13.492 1.00 53.58 ? 231 ARG A N 1 ATOM 1446 C CA . ARG A 1 233 ? 11.317 57.111 -13.781 1.00 52.97 ? 231 ARG A CA 1 ATOM 1447 C C . ARG A 1 233 ? 11.344 58.477 -14.474 1.00 57.27 ? 231 ARG A C 1 ATOM 1448 O O . ARG A 1 233 ? 12.417 58.926 -14.890 1.00 57.07 ? 231 ARG A O 1 ATOM 1449 C CB . ARG A 1 233 ? 12.098 56.042 -14.557 1.00 51.06 ? 231 ARG A CB 1 ATOM 1450 C CG . ARG A 1 233 ? 12.733 55.011 -13.632 1.00 54.63 ? 231 ARG A CG 1 ATOM 1451 C CD . ARG A 1 233 ? 13.013 53.732 -14.365 1.00 48.45 ? 231 ARG A CD 1 ATOM 1452 N NE . ARG A 1 233 ? 13.290 52.597 -13.478 1.00 46.38 ? 231 ARG A NE 1 ATOM 1453 C CZ . ARG A 1 233 ? 12.375 51.732 -13.035 1.00 56.64 ? 231 ARG A CZ 1 ATOM 1454 N NH1 . ARG A 1 233 ? 11.096 51.887 -13.347 1.00 43.51 ? 231 ARG A NH1 1 ATOM 1455 N NH2 . ARG A 1 233 ? 12.735 50.704 -12.289 1.00 44.76 ? 231 ARG A NH2 1 ATOM 1456 N N . ASN A 1 234 ? 10.170 59.158 -14.541 1.00 54.03 ? 232 ASN A N 1 ATOM 1457 C CA . ASN A 1 234 ? 9.971 60.478 -15.159 1.00 54.68 ? 232 ASN A CA 1 ATOM 1458 C C . ASN A 1 234 ? 10.235 60.451 -16.687 1.00 58.89 ? 232 ASN A C 1 ATOM 1459 O O . ASN A 1 234 ? 10.845 61.365 -17.256 1.00 59.34 ? 232 ASN A O 1 ATOM 1460 C CB . ASN A 1 234 ? 10.757 61.600 -14.425 1.00 57.68 ? 232 ASN A CB 1 ATOM 1461 C CG . ASN A 1 234 ? 10.018 62.238 -13.261 1.00 97.34 ? 232 ASN A CG 1 ATOM 1462 O OD1 . ASN A 1 234 ? 9.334 61.579 -12.457 1.00 89.39 ? 232 ASN A OD1 1 ATOM 1463 N ND2 . ASN A 1 234 ? 10.170 63.551 -13.125 1.00 97.69 ? 232 ASN A ND2 1 ATOM 1464 N N . ILE A 1 235 ? 9.743 59.386 -17.338 1.00 55.01 ? 233 ILE A N 1 ATOM 1465 C CA . ILE A 1 235 ? 9.793 59.161 -18.785 1.00 54.32 ? 233 ILE A CA 1 ATOM 1466 C C . ILE A 1 235 ? 8.347 59.265 -19.249 1.00 57.01 ? 233 ILE A C 1 ATOM 1467 O O . ILE A 1 235 ? 7.501 58.546 -18.720 1.00 55.96 ? 233 ILE A O 1 ATOM 1468 C CB . ILE A 1 235 ? 10.396 57.762 -19.163 1.00 57.26 ? 233 ILE A CB 1 ATOM 1469 C CG1 . ILE A 1 235 ? 11.815 57.576 -18.586 1.00 57.38 ? 233 ILE A CG1 1 ATOM 1470 C CG2 . ILE A 1 235 ? 10.369 57.552 -20.705 1.00 57.24 ? 233 ILE A CG2 1 ATOM 1471 C CD1 . ILE A 1 235 ? 12.269 56.147 -18.379 1.00 62.85 ? 233 ILE A CD1 1 ATOM 1472 N N . SER A 1 236 ? 8.061 60.149 -20.217 1.00 53.96 ? 234 SER A N 1 ATOM 1473 C CA . SER A 1 236 ? 6.701 60.312 -20.738 1.00 53.67 ? 234 SER A CA 1 ATOM 1474 C C . SER A 1 236 ? 6.511 59.576 -22.068 1.00 54.00 ? 234 SER A C 1 ATOM 1475 O O . SER A 1 236 ? 7.489 59.346 -22.786 1.00 52.17 ? 234 SER A O 1 ATOM 1476 C CB . SER A 1 236 ? 6.278 61.785 -20.810 1.00 58.05 ? 234 SER A CB 1 ATOM 1477 O OG . SER A 1 236 ? 7.219 62.625 -21.454 1.00 71.73 ? 234 SER A OG 1 ATOM 1478 N N . VAL A 1 237 ? 5.255 59.189 -22.364 1.00 48.65 ? 235 VAL A N 1 ATOM 1479 C CA . VAL A 1 237 ? 4.871 58.416 -23.546 1.00 48.13 ? 235 VAL A CA 1 ATOM 1480 C C . VAL A 1 237 ? 4.045 59.284 -24.499 1.00 51.93 ? 235 VAL A C 1 ATOM 1481 O O . VAL A 1 237 ? 2.901 59.657 -24.199 1.00 53.27 ? 235 VAL A O 1 ATOM 1482 C CB . VAL A 1 237 ? 4.208 57.047 -23.170 1.00 51.36 ? 235 VAL A CB 1 ATOM 1483 C CG1 . VAL A 1 237 ? 3.415 56.441 -24.323 1.00 50.75 ? 235 VAL A CG1 1 ATOM 1484 C CG2 . VAL A 1 237 ? 5.262 56.064 -22.677 1.00 51.13 ? 235 VAL A CG2 1 ATOM 1485 N N . ALA A 1 238 ? 4.668 59.590 -25.652 1.00 45.29 ? 236 ALA A N 1 ATOM 1486 C CA . ALA A 1 238 ? 4.206 60.460 -26.721 1.00 44.32 ? 236 ALA A CA 1 ATOM 1487 C C . ALA A 1 238 ? 2.919 60.006 -27.362 1.00 48.48 ? 236 ALA A C 1 ATOM 1488 O O . ALA A 1 238 ? 2.032 60.818 -27.599 1.00 47.73 ? 236 ALA A O 1 ATOM 1489 C CB . ALA A 1 238 ? 5.307 60.610 -27.772 1.00 44.80 ? 236 ALA A CB 1 ATOM 1490 N N . THR A 1 239 ? 2.853 58.699 -27.678 1.00 46.27 ? 237 THR A N 1 ATOM 1491 C CA . THR A 1 239 ? 1.792 57.931 -28.331 1.00 45.05 ? 237 THR A CA 1 ATOM 1492 C C . THR A 1 239 ? 2.098 56.458 -28.046 1.00 48.93 ? 237 THR A C 1 ATOM 1493 O O . THR A 1 239 ? 3.262 56.091 -27.805 1.00 49.11 ? 237 THR A O 1 ATOM 1494 C CB . THR A 1 239 ? 1.748 58.228 -29.856 1.00 53.35 ? 237 THR A CB 1 ATOM 1495 O OG1 . THR A 1 239 ? 0.582 57.637 -30.434 1.00 55.96 ? 237 THR A OG1 1 ATOM 1496 C CG2 . THR A 1 239 ? 3.012 57.775 -30.616 1.00 47.24 ? 237 THR A CG2 1 ATOM 1497 N N . SER A 1 240 ? 1.054 55.629 -28.079 1.00 44.16 ? 238 SER A N 1 ATOM 1498 C CA . SER A 1 240 ? 1.117 54.200 -27.833 1.00 43.31 ? 238 SER A CA 1 ATOM 1499 C C . SER A 1 240 ? 0.363 53.591 -28.960 1.00 47.51 ? 238 SER A C 1 ATOM 1500 O O . SER A 1 240 ? -0.795 53.957 -29.209 1.00 47.34 ? 238 SER A O 1 ATOM 1501 C CB . SER A 1 240 ? 0.408 53.841 -26.527 1.00 47.49 ? 238 SER A CB 1 ATOM 1502 O OG . SER A 1 240 ? 0.902 54.544 -25.400 1.00 60.58 ? 238 SER A OG 1 ATOM 1503 N N . GLU A 1 241 ? 0.978 52.629 -29.631 1.00 43.96 ? 239 GLU A N 1 ATOM 1504 C CA . GLU A 1 241 ? 0.309 52.016 -30.761 1.00 43.21 ? 239 GLU A CA 1 ATOM 1505 C C . GLU A 1 241 ? 0.069 50.526 -30.573 1.00 46.77 ? 239 GLU A C 1 ATOM 1506 O O . GLU A 1 241 ? 0.748 49.848 -29.785 1.00 43.50 ? 239 GLU A O 1 ATOM 1507 C CB . GLU A 1 241 ? 1.048 52.327 -32.070 1.00 44.47 ? 239 GLU A CB 1 ATOM 1508 C CG . GLU A 1 241 ? 1.256 53.815 -32.335 1.00 53.14 ? 239 GLU A CG 1 ATOM 1509 C CD . GLU A 1 241 ? -0.017 54.604 -32.579 1.00 67.58 ? 239 GLU A CD 1 ATOM 1510 O OE1 . GLU A 1 241 ? -0.968 54.036 -33.163 1.00 56.07 ? 239 GLU A OE1 1 ATOM 1511 O OE2 . GLU A 1 241 ? -0.052 55.802 -32.218 1.00 58.70 ? 239 GLU A OE2 1 ATOM 1512 N N . LYS A 1 242 ? -0.925 50.039 -31.315 1.00 45.61 ? 240 LYS A N 1 ATOM 1513 C CA . LYS A 1 242 ? -1.386 48.670 -31.303 1.00 46.71 ? 240 LYS A CA 1 ATOM 1514 C C . LYS A 1 242 ? -1.240 48.070 -32.685 1.00 51.67 ? 240 LYS A C 1 ATOM 1515 O O . LYS A 1 242 ? -1.628 48.684 -33.678 1.00 52.64 ? 240 LYS A O 1 ATOM 1516 C CB . LYS A 1 242 ? -2.845 48.614 -30.826 1.00 49.80 ? 240 LYS A CB 1 ATOM 1517 C CG . LYS A 1 242 ? -3.350 47.210 -30.477 1.00 74.36 ? 240 LYS A CG 1 ATOM 1518 C CD . LYS A 1 242 ? -4.740 47.256 -29.796 1.00 88.25 ? 240 LYS A CD 1 ATOM 1519 C CE . LYS A 1 242 ? -5.895 47.565 -30.732 1.00 91.81 ? 240 LYS A CE 1 ATOM 1520 N NZ . LYS A 1 242 ? -7.015 48.235 -30.018 1.00 97.22 ? 240 LYS A NZ 1 ATOM 1521 N N . VAL A 1 243 ? -0.660 46.876 -32.745 1.00 47.41 ? 241 VAL A N 1 ATOM 1522 C CA . VAL A 1 243 ? -0.486 46.150 -33.984 1.00 46.77 ? 241 VAL A CA 1 ATOM 1523 C C . VAL A 1 243 ? -1.491 45.035 -33.951 1.00 55.61 ? 241 VAL A C 1 ATOM 1524 O O . VAL A 1 243 ? -1.384 44.145 -33.105 1.00 57.34 ? 241 VAL A O 1 ATOM 1525 C CB . VAL A 1 243 ? 0.965 45.672 -34.200 1.00 48.24 ? 241 VAL A CB 1 ATOM 1526 C CG1 . VAL A 1 243 ? 1.050 44.721 -35.385 1.00 47.04 ? 241 VAL A CG1 1 ATOM 1527 C CG2 . VAL A 1 243 ? 1.888 46.864 -34.405 1.00 47.61 ? 241 VAL A CG2 1 ATOM 1528 N N . GLY A 1 244 ? -2.483 45.126 -34.837 1.00 53.21 ? 242 GLY A N 1 ATOM 1529 C CA . GLY A 1 244 ? -3.595 44.187 -34.936 1.00 54.28 ? 242 GLY A CA 1 ATOM 1530 C C . GLY A 1 244 ? -3.232 42.756 -35.282 1.00 63.17 ? 242 GLY A C 1 ATOM 1531 O O . GLY A 1 244 ? -2.052 42.423 -35.474 1.00 63.04 ? 242 GLY A O 1 ATOM 1532 N N . ARG A 1 245 ? -4.277 41.902 -35.375 1.00 62.98 ? 243 ARG A N 1 ATOM 1533 C CA . ARG A 1 245 ? -4.164 40.466 -35.647 1.00 63.81 ? 243 ARG A CA 1 ATOM 1534 C C . ARG A 1 245 ? -3.977 40.132 -37.135 1.00 70.08 ? 243 ARG A C 1 ATOM 1535 O O . ARG A 1 245 ? -3.339 39.117 -37.445 1.00 71.12 ? 243 ARG A O 1 ATOM 1536 C CB . ARG A 1 245 ? -5.357 39.710 -35.038 1.00 63.72 ? 243 ARG A CB 1 ATOM 1537 C CG . ARG A 1 245 ? -5.408 39.816 -33.500 1.00 72.28 ? 243 ARG A CG 1 ATOM 1538 C CD . ARG A 1 245 ? -6.705 39.308 -32.871 1.00 69.48 ? 243 ARG A CD 1 ATOM 1539 N NE . ARG A 1 245 ? -7.043 37.940 -33.275 1.00 60.48 ? 243 ARG A NE 1 ATOM 1540 C CZ . ARG A 1 245 ? -6.589 36.839 -32.682 1.00 66.94 ? 243 ARG A CZ 1 ATOM 1541 N NH1 . ARG A 1 245 ? -5.783 36.926 -31.628 1.00 54.38 ? 243 ARG A NH1 1 ATOM 1542 N NH2 . ARG A 1 245 ? -6.954 35.642 -33.124 1.00 50.06 ? 243 ARG A NH2 1 ATOM 1543 N N . ALA A 1 246 ? -4.522 40.973 -38.050 1.00 66.52 ? 244 ALA A N 1 ATOM 1544 C CA . ALA A 1 246 ? -4.388 40.790 -39.508 1.00 66.18 ? 244 ALA A CA 1 ATOM 1545 C C . ALA A 1 246 ? -4.108 42.141 -40.164 1.00 68.14 ? 244 ALA A C 1 ATOM 1546 O O . ALA A 1 246 ? -5.008 42.794 -40.707 1.00 68.83 ? 244 ALA A O 1 ATOM 1547 C CB . ALA A 1 246 ? -5.643 40.154 -40.090 1.00 67.13 ? 244 ALA A CB 1 ATOM 1548 N N . MET A 1 247 ? -2.847 42.572 -40.077 1.00 61.23 ? 245 MET A N 1 ATOM 1549 C CA . MET A 1 247 ? -2.429 43.869 -40.585 1.00 59.02 ? 245 MET A CA 1 ATOM 1550 C C . MET A 1 247 ? -1.864 43.818 -42.002 1.00 60.05 ? 245 MET A C 1 ATOM 1551 O O . MET A 1 247 ? -1.166 42.871 -42.368 1.00 60.01 ? 245 MET A O 1 ATOM 1552 C CB . MET A 1 247 ? -1.431 44.505 -39.615 1.00 60.77 ? 245 MET A CB 1 ATOM 1553 C CG . MET A 1 247 ? -2.083 45.159 -38.440 1.00 63.67 ? 245 MET A CG 1 ATOM 1554 S SD . MET A 1 247 ? -1.302 46.734 -38.058 1.00 67.71 ? 245 MET A SD 1 ATOM 1555 C CE . MET A 1 247 ? -2.656 47.583 -37.378 1.00 64.90 ? 245 MET A CE 1 ATOM 1556 N N . SER A 1 248 ? -2.170 44.843 -42.796 1.00 53.28 ? 246 SER A N 1 ATOM 1557 C CA . SER A 1 248 ? -1.670 44.964 -44.163 1.00 51.40 ? 246 SER A CA 1 ATOM 1558 C C . SER A 1 248 ? -0.383 45.791 -44.129 1.00 51.93 ? 246 SER A C 1 ATOM 1559 O O . SER A 1 248 ? -0.055 46.333 -43.079 1.00 53.10 ? 246 SER A O 1 ATOM 1560 C CB . SER A 1 248 ? -2.714 45.641 -45.042 1.00 53.88 ? 246 SER A CB 1 ATOM 1561 O OG . SER A 1 248 ? -3.086 46.905 -44.514 1.00 61.61 ? 246 SER A OG 1 ATOM 1562 N N . ARG A 1 249 ? 0.352 45.881 -45.250 1.00 44.72 ? 247 ARG A N 1 ATOM 1563 C CA . ARG A 1 249 ? 1.568 46.698 -45.318 1.00 43.63 ? 247 ARG A CA 1 ATOM 1564 C C . ARG A 1 249 ? 1.206 48.175 -45.106 1.00 44.35 ? 247 ARG A C 1 ATOM 1565 O O . ARG A 1 249 ? 1.941 48.866 -44.423 1.00 41.68 ? 247 ARG A O 1 ATOM 1566 C CB . ARG A 1 249 ? 2.266 46.524 -46.667 1.00 44.06 ? 247 ARG A CB 1 ATOM 1567 C CG . ARG A 1 249 ? 3.055 45.253 -46.762 1.00 49.52 ? 247 ARG A CG 1 ATOM 1568 C CD . ARG A 1 249 ? 3.437 44.977 -48.187 1.00 54.34 ? 247 ARG A CD 1 ATOM 1569 N NE . ARG A 1 249 ? 4.564 44.057 -48.230 1.00 61.40 ? 247 ARG A NE 1 ATOM 1570 C CZ . ARG A 1 249 ? 5.441 43.987 -49.223 1.00 70.05 ? 247 ARG A CZ 1 ATOM 1571 N NH1 . ARG A 1 249 ? 6.441 43.120 -49.170 1.00 61.54 ? 247 ARG A NH1 1 ATOM 1572 N NH2 . ARG A 1 249 ? 5.330 44.787 -50.273 1.00 51.83 ? 247 ARG A NH2 1 ATOM 1573 N N . ALA A 1 250 ? 0.045 48.624 -45.651 1.00 40.66 ? 248 ALA A N 1 ATOM 1574 C CA . ALA A 1 250 ? -0.507 49.974 -45.491 1.00 40.84 ? 248 ALA A CA 1 ATOM 1575 C C . ALA A 1 250 ? -0.857 50.250 -44.005 1.00 45.34 ? 248 ALA A C 1 ATOM 1576 O O . ALA A 1 250 ? -0.704 51.385 -43.500 1.00 45.20 ? 248 ALA A O 1 ATOM 1577 C CB . ALA A 1 250 ? -1.762 50.115 -46.346 1.00 41.40 ? 248 ALA A CB 1 ATOM 1578 N N . ALA A 1 251 ? -1.326 49.199 -43.307 1.00 39.94 ? 249 ALA A N 1 ATOM 1579 C CA . ALA A 1 251 ? -1.680 49.344 -41.908 1.00 38.82 ? 249 ALA A CA 1 ATOM 1580 C C . ALA A 1 251 ? -0.403 49.601 -41.136 1.00 40.84 ? 249 ALA A C 1 ATOM 1581 O O . ALA A 1 251 ? -0.357 50.551 -40.349 1.00 41.58 ? 249 ALA A O 1 ATOM 1582 C CB . ALA A 1 251 ? -2.401 48.101 -41.404 1.00 39.44 ? 249 ALA A CB 1 ATOM 1583 N N . PHE A 1 252 ? 0.665 48.836 -41.449 1.00 35.43 ? 250 PHE A N 1 ATOM 1584 C CA . PHE A 1 252 ? 1.976 48.987 -40.813 1.00 35.10 ? 250 PHE A CA 1 ATOM 1585 C C . PHE A 1 252 ? 2.604 50.368 -41.007 1.00 40.09 ? 250 PHE A C 1 ATOM 1586 O O . PHE A 1 252 ? 3.191 50.914 -40.079 1.00 40.92 ? 250 PHE A O 1 ATOM 1587 C CB . PHE A 1 252 ? 2.926 47.879 -41.230 1.00 36.01 ? 250 PHE A CB 1 ATOM 1588 C CG . PHE A 1 252 ? 2.779 46.703 -40.312 1.00 36.29 ? 250 PHE A CG 1 ATOM 1589 C CD1 . PHE A 1 252 ? 3.307 46.736 -39.025 1.00 37.01 ? 250 PHE A CD1 1 ATOM 1590 C CD2 . PHE A 1 252 ? 2.065 45.576 -40.709 1.00 37.96 ? 250 PHE A CD2 1 ATOM 1591 C CE1 . PHE A 1 252 ? 3.128 45.663 -38.152 1.00 36.88 ? 250 PHE A CE1 1 ATOM 1592 C CE2 . PHE A 1 252 ? 1.904 44.493 -39.837 1.00 39.25 ? 250 PHE A CE2 1 ATOM 1593 C CZ . PHE A 1 252 ? 2.454 44.538 -38.573 1.00 36.14 ? 250 PHE A CZ 1 ATOM 1594 N N . GLU A 1 253 ? 2.403 50.947 -42.167 1.00 38.39 ? 251 GLU A N 1 ATOM 1595 C CA . GLU A 1 253 ? 2.847 52.280 -42.542 1.00 39.21 ? 251 GLU A CA 1 ATOM 1596 C C . GLU A 1 253 ? 2.057 53.284 -41.715 1.00 46.87 ? 251 GLU A C 1 ATOM 1597 O O . GLU A 1 253 ? 2.653 54.217 -41.167 1.00 45.93 ? 251 GLU A O 1 ATOM 1598 C CB . GLU A 1 253 ? 2.580 52.483 -44.038 1.00 40.37 ? 251 GLU A CB 1 ATOM 1599 C CG . GLU A 1 253 ? 3.549 51.717 -44.929 1.00 44.39 ? 251 GLU A CG 1 ATOM 1600 C CD . GLU A 1 253 ? 3.212 51.540 -46.398 1.00 63.45 ? 251 GLU A CD 1 ATOM 1601 O OE1 . GLU A 1 253 ? 2.331 52.263 -46.926 1.00 64.48 ? 251 GLU A OE1 1 ATOM 1602 O OE2 . GLU A 1 253 ? 3.873 50.685 -47.033 1.00 52.13 ? 251 GLU A OE2 1 ATOM 1603 N N . GLY A 1 254 ? 0.737 53.026 -41.580 1.00 45.26 ? 252 GLY A N 1 ATOM 1604 C CA . GLY A 1 254 ? -0.185 53.837 -40.791 1.00 45.29 ? 252 GLY A CA 1 ATOM 1605 C C . GLY A 1 254 ? 0.373 54.027 -39.403 1.00 52.57 ? 252 GLY A C 1 ATOM 1606 O O . GLY A 1 254 ? 0.519 55.169 -38.942 1.00 54.40 ? 252 GLY A O 1 ATOM 1607 N N . VAL A 1 255 ? 0.791 52.892 -38.772 1.00 48.27 ? 253 VAL A N 1 ATOM 1608 C CA . VAL A 1 255 ? 1.444 52.872 -37.465 1.00 47.02 ? 253 VAL A CA 1 ATOM 1609 C C . VAL A 1 255 ? 2.670 53.754 -37.512 1.00 49.11 ? 253 VAL A C 1 ATOM 1610 O O . VAL A 1 255 ? 2.772 54.626 -36.657 1.00 51.16 ? 253 VAL A O 1 ATOM 1611 C CB . VAL A 1 255 ? 1.787 51.445 -36.935 1.00 51.30 ? 253 VAL A CB 1 ATOM 1612 C CG1 . VAL A 1 255 ? 2.662 51.507 -35.678 1.00 51.15 ? 253 VAL A CG1 1 ATOM 1613 C CG2 . VAL A 1 255 ? 0.528 50.648 -36.641 1.00 51.28 ? 253 VAL A CG2 1 ATOM 1614 N N . VAL A 1 256 ? 3.586 53.562 -38.499 1.00 42.06 ? 254 VAL A N 1 ATOM 1615 C CA . VAL A 1 256 ? 4.833 54.348 -38.560 1.00 41.17 ? 254 VAL A CA 1 ATOM 1616 C C . VAL A 1 256 ? 4.546 55.858 -38.674 1.00 45.57 ? 254 VAL A C 1 ATOM 1617 O O . VAL A 1 256 ? 5.215 56.668 -38.032 1.00 44.62 ? 254 VAL A O 1 ATOM 1618 C CB . VAL A 1 256 ? 5.822 53.838 -39.643 1.00 43.88 ? 254 VAL A CB 1 ATOM 1619 C CG1 . VAL A 1 256 ? 7.045 54.747 -39.760 1.00 42.98 ? 254 VAL A CG1 1 ATOM 1620 C CG2 . VAL A 1 256 ? 6.251 52.388 -39.368 1.00 43.19 ? 254 VAL A CG2 1 ATOM 1621 N N . ARG A 1 257 ? 3.514 56.214 -39.432 1.00 43.50 ? 255 ARG A N 1 ATOM 1622 C CA . ARG A 1 257 ? 3.090 57.596 -39.629 1.00 43.28 ? 255 ARG A CA 1 ATOM 1623 C C . ARG A 1 257 ? 2.613 58.207 -38.316 1.00 46.49 ? 255 ARG A C 1 ATOM 1624 O O . ARG A 1 257 ? 2.931 59.368 -38.036 1.00 45.73 ? 255 ARG A O 1 ATOM 1625 C CB . ARG A 1 257 ? 2.028 57.688 -40.739 1.00 41.57 ? 255 ARG A CB 1 ATOM 1626 C CG . ARG A 1 257 ? 2.632 57.611 -42.132 1.00 45.55 ? 255 ARG A CG 1 ATOM 1627 C CD . ARG A 1 257 ? 1.573 57.745 -43.212 1.00 46.65 ? 255 ARG A CD 1 ATOM 1628 N NE . ARG A 1 257 ? 2.159 57.777 -44.554 1.00 42.64 ? 255 ARG A NE 1 ATOM 1629 C CZ . ARG A 1 257 ? 2.086 56.784 -45.435 1.00 66.82 ? 255 ARG A CZ 1 ATOM 1630 N NH1 . ARG A 1 257 ? 1.457 55.655 -45.126 1.00 58.92 ? 255 ARG A NH1 1 ATOM 1631 N NH2 . ARG A 1 257 ? 2.638 56.912 -46.635 1.00 58.79 ? 255 ARG A NH2 1 ATOM 1632 N N . ALA A 1 258 ? 1.917 57.401 -37.487 1.00 43.50 ? 256 ALA A N 1 ATOM 1633 C CA . ALA A 1 258 ? 1.438 57.809 -36.153 1.00 43.50 ? 256 ALA A CA 1 ATOM 1634 C C . ALA A 1 258 ? 2.611 58.116 -35.213 1.00 48.19 ? 256 ALA A C 1 ATOM 1635 O O . ALA A 1 258 ? 2.529 59.065 -34.441 1.00 48.33 ? 256 ALA A O 1 ATOM 1636 C CB . ALA A 1 258 ? 0.538 56.739 -35.556 1.00 43.67 ? 256 ALA A CB 1 ATOM 1637 N N . LEU A 1 259 ? 3.711 57.338 -35.318 1.00 45.69 ? 257 LEU A N 1 ATOM 1638 C CA . LEU A 1 259 ? 4.955 57.527 -34.568 1.00 46.06 ? 257 LEU A CA 1 ATOM 1639 C C . LEU A 1 259 ? 5.673 58.767 -35.067 1.00 52.72 ? 257 LEU A C 1 ATOM 1640 O O . LEU A 1 259 ? 6.261 59.494 -34.257 1.00 54.32 ? 257 LEU A O 1 ATOM 1641 C CB . LEU A 1 259 ? 5.891 56.308 -34.668 1.00 45.85 ? 257 LEU A CB 1 ATOM 1642 C CG . LEU A 1 259 ? 5.386 54.969 -34.071 1.00 49.98 ? 257 LEU A CG 1 ATOM 1643 C CD1 . LEU A 1 259 ? 6.345 53.830 -34.381 1.00 49.56 ? 257 LEU A CD1 1 ATOM 1644 C CD2 . LEU A 1 259 ? 5.139 55.055 -32.569 1.00 49.78 ? 257 LEU A CD2 1 ATOM 1645 N N . LEU A 1 260 ? 5.608 59.027 -36.394 1.00 48.80 ? 258 LEU A N 1 ATOM 1646 C CA . LEU A 1 260 ? 6.204 60.213 -37.030 1.00 47.70 ? 258 LEU A CA 1 ATOM 1647 C C . LEU A 1 260 ? 5.464 61.545 -36.680 1.00 54.90 ? 258 LEU A C 1 ATOM 1648 O O . LEU A 1 260 ? 6.033 62.629 -36.847 1.00 54.08 ? 258 LEU A O 1 ATOM 1649 C CB . LEU A 1 260 ? 6.347 60.024 -38.554 1.00 46.11 ? 258 LEU A CB 1 ATOM 1650 C CG . LEU A 1 260 ? 7.435 59.046 -39.025 1.00 47.37 ? 258 LEU A CG 1 ATOM 1651 C CD1 . LEU A 1 260 ? 7.238 58.670 -40.460 1.00 45.66 ? 258 LEU A CD1 1 ATOM 1652 C CD2 . LEU A 1 260 ? 8.847 59.548 -38.746 1.00 45.05 ? 258 LEU A CD2 1 ATOM 1653 N N . GLN A 1 261 ? 4.238 61.458 -36.139 1.00 54.40 ? 259 GLN A N 1 ATOM 1654 C CA . GLN A 1 261 ? 3.472 62.634 -35.727 1.00 56.16 ? 259 GLN A CA 1 ATOM 1655 C C . GLN A 1 261 ? 4.068 63.333 -34.487 1.00 65.96 ? 259 GLN A C 1 ATOM 1656 O O . GLN A 1 261 ? 3.826 64.530 -34.288 1.00 66.15 ? 259 GLN A O 1 ATOM 1657 C CB . GLN A 1 261 ? 2.003 62.278 -35.505 1.00 57.20 ? 259 GLN A CB 1 ATOM 1658 C CG . GLN A 1 261 ? 1.265 62.041 -36.813 1.00 67.84 ? 259 GLN A CG 1 ATOM 1659 C CD . GLN A 1 261 ? -0.180 61.713 -36.583 1.00 90.95 ? 259 GLN A CD 1 ATOM 1660 O OE1 . GLN A 1 261 ? -0.589 60.545 -36.600 1.00 87.06 ? 259 GLN A OE1 1 ATOM 1661 N NE2 . GLN A 1 261 ? -0.987 62.744 -36.382 1.00 85.33 ? 259 GLN A NE2 1 ATOM 1662 N N . LYS A 1 262 ? 4.862 62.588 -33.676 1.00 65.40 ? 260 LYS A N 1 ATOM 1663 C CA . LYS A 1 262 ? 5.563 63.077 -32.472 1.00 65.76 ? 260 LYS A CA 1 ATOM 1664 C C . LYS A 1 262 ? 7.067 63.035 -32.824 1.00 70.64 ? 260 LYS A C 1 ATOM 1665 O O . LYS A 1 262 ? 7.717 62.013 -32.589 1.00 70.78 ? 260 LYS A O 1 ATOM 1666 C CB . LYS A 1 262 ? 5.242 62.199 -31.228 1.00 67.52 ? 260 LYS A CB 1 ATOM 1667 C CG . LYS A 1 262 ? 3.791 61.686 -31.088 1.00 65.71 ? 260 LYS A CG 1 ATOM 1668 C CD . LYS A 1 262 ? 2.748 62.766 -30.807 1.00 61.54 ? 260 LYS A CD 1 ATOM 1669 C CE . LYS A 1 262 ? 1.367 62.154 -30.806 1.00 63.21 ? 260 LYS A CE 1 ATOM 1670 N NZ . LYS A 1 262 ? 0.356 63.013 -31.499 1.00 65.60 ? 260 LYS A NZ 1 ATOM 1671 N N . PRO A 1 263 ? 7.602 64.096 -33.485 1.00 67.70 ? 261 PRO A N 1 ATOM 1672 C CA . PRO A 1 263 ? 8.997 64.040 -33.991 1.00 67.31 ? 261 PRO A CA 1 ATOM 1673 C C . PRO A 1 263 ? 10.125 64.003 -32.962 1.00 70.44 ? 261 PRO A C 1 ATOM 1674 O O . PRO A 1 263 ? 11.224 63.548 -33.304 1.00 70.22 ? 261 PRO A O 1 ATOM 1675 C CB . PRO A 1 263 ? 9.121 65.288 -34.872 1.00 68.86 ? 261 PRO A CB 1 ATOM 1676 C CG . PRO A 1 263 ? 7.738 65.794 -35.053 1.00 73.58 ? 261 PRO A CG 1 ATOM 1677 C CD . PRO A 1 263 ? 6.941 65.354 -33.883 1.00 69.22 ? 261 PRO A CD 1 ATOM 1678 N N . SER A 1 264 ? 9.874 64.495 -31.731 1.00 65.66 ? 262 SER A N 1 ATOM 1679 C CA . SER A 1 264 ? 10.861 64.522 -30.642 1.00 64.29 ? 262 SER A CA 1 ATOM 1680 C C . SER A 1 264 ? 11.158 63.101 -30.137 1.00 67.87 ? 262 SER A C 1 ATOM 1681 O O . SER A 1 264 ? 12.328 62.777 -29.891 1.00 68.36 ? 262 SER A O 1 ATOM 1682 C CB . SER A 1 264 ? 10.374 65.399 -29.498 1.00 65.40 ? 262 SER A CB 1 ATOM 1683 O OG . SER A 1 264 ? 9.810 66.594 -30.006 1.00 70.48 ? 262 SER A OG 1 ATOM 1684 N N . ALA A 1 265 ? 10.098 62.248 -30.010 1.00 61.63 ? 263 ALA A N 1 ATOM 1685 C CA . ALA A 1 265 ? 10.233 60.854 -29.584 1.00 59.54 ? 263 ALA A CA 1 ATOM 1686 C C . ALA A 1 265 ? 10.893 60.065 -30.716 1.00 58.61 ? 263 ALA A C 1 ATOM 1687 O O . ALA A 1 265 ? 10.251 59.742 -31.721 1.00 56.64 ? 263 ALA A O 1 ATOM 1688 C CB . ALA A 1 265 ? 8.873 60.266 -29.235 1.00 60.27 ? 263 ALA A CB 1 ATOM 1689 N N . ARG A 1 266 ? 12.208 59.853 -30.588 1.00 52.88 ? 264 ARG A N 1 ATOM 1690 C CA . ARG A 1 266 ? 12.987 59.124 -31.584 1.00 51.72 ? 264 ARG A CA 1 ATOM 1691 C C . ARG A 1 266 ? 13.198 57.681 -31.123 1.00 51.47 ? 264 ARG A C 1 ATOM 1692 O O . ARG A 1 266 ? 13.731 56.846 -31.851 1.00 50.56 ? 264 ARG A O 1 ATOM 1693 C CB . ARG A 1 266 ? 14.315 59.851 -31.875 1.00 53.65 ? 264 ARG A CB 1 ATOM 1694 N N . VAL A 1 267 ? 12.737 57.392 -29.912 1.00 45.61 ? 265 VAL A N 1 ATOM 1695 C CA . VAL A 1 267 ? 12.801 56.076 -29.293 1.00 42.71 ? 265 VAL A CA 1 ATOM 1696 C C . VAL A 1 267 ? 11.426 55.449 -29.415 1.00 44.87 ? 265 VAL A C 1 ATOM 1697 O O . VAL A 1 267 ? 10.409 56.088 -29.082 1.00 43.26 ? 265 VAL A O 1 ATOM 1698 C CB . VAL A 1 267 ? 13.311 56.127 -27.830 1.00 43.56 ? 265 VAL A CB 1 ATOM 1699 C CG1 . VAL A 1 267 ? 13.327 54.736 -27.206 1.00 42.78 ? 265 VAL A CG1 1 ATOM 1700 C CG2 . VAL A 1 267 ? 14.701 56.771 -27.759 1.00 42.76 ? 265 VAL A CG2 1 ATOM 1701 N N . ALA A 1 268 ? 11.410 54.208 -29.941 1.00 40.37 ? 266 ALA A N 1 ATOM 1702 C CA . ALA A 1 268 ? 10.213 53.394 -30.122 1.00 39.88 ? 266 ALA A CA 1 ATOM 1703 C C . ALA A 1 268 ? 10.435 52.097 -29.383 1.00 42.78 ? 266 ALA A C 1 ATOM 1704 O O . ALA A 1 268 ? 11.328 51.308 -29.743 1.00 41.57 ? 266 ALA A O 1 ATOM 1705 C CB . ALA A 1 268 ? 9.943 53.140 -31.601 1.00 40.75 ? 266 ALA A CB 1 ATOM 1706 N N . VAL A 1 269 ? 9.677 51.947 -28.273 1.00 38.12 ? 267 VAL A N 1 ATOM 1707 C CA . VAL A 1 269 ? 9.713 50.819 -27.345 1.00 36.70 ? 267 VAL A CA 1 ATOM 1708 C C . VAL A 1 269 ? 8.653 49.842 -27.813 1.00 37.73 ? 267 VAL A C 1 ATOM 1709 O O . VAL A 1 269 ? 7.489 50.203 -27.919 1.00 37.22 ? 267 VAL A O 1 ATOM 1710 C CB . VAL A 1 269 ? 9.521 51.285 -25.857 1.00 40.05 ? 267 VAL A CB 1 ATOM 1711 C CG1 . VAL A 1 269 ? 9.517 50.106 -24.880 1.00 38.75 ? 267 VAL A CG1 1 ATOM 1712 C CG2 . VAL A 1 269 ? 10.582 52.327 -25.456 1.00 39.40 ? 267 VAL A CG2 1 ATOM 1713 N N . LEU A 1 270 ? 9.059 48.625 -28.090 1.00 33.47 ? 268 LEU A N 1 ATOM 1714 C CA . LEU A 1 270 ? 8.168 47.606 -28.579 1.00 32.96 ? 268 LEU A CA 1 ATOM 1715 C C . LEU A 1 270 ? 8.110 46.339 -27.776 1.00 35.00 ? 268 LEU A C 1 ATOM 1716 O O . LEU A 1 270 ? 9.097 45.816 -27.372 1.00 32.86 ? 268 LEU A O 1 ATOM 1717 C CB . LEU A 1 270 ? 8.585 47.193 -29.963 1.00 32.96 ? 268 LEU A CB 1 ATOM 1718 C CG . LEU A 1 270 ? 8.338 48.031 -31.180 1.00 37.52 ? 268 LEU A CG 1 ATOM 1719 C CD1 . LEU A 1 270 ? 8.430 49.496 -30.876 1.00 37.67 ? 268 LEU A CD1 1 ATOM 1720 C CD2 . LEU A 1 270 ? 9.386 47.631 -32.167 1.00 38.63 ? 268 LEU A CD2 1 ATOM 1721 N N . PHE A 1 271 ? 6.902 45.832 -27.632 1.00 33.86 ? 269 PHE A N 1 ATOM 1722 C CA . PHE A 1 271 ? 6.577 44.562 -26.997 1.00 35.44 ? 269 PHE A CA 1 ATOM 1723 C C . PHE A 1 271 ? 5.785 43.828 -28.083 1.00 44.44 ? 269 PHE A C 1 ATOM 1724 O O . PHE A 1 271 ? 4.553 43.780 -28.064 1.00 45.06 ? 269 PHE A O 1 ATOM 1725 C CB . PHE A 1 271 ? 5.735 44.782 -25.726 1.00 37.31 ? 269 PHE A CB 1 ATOM 1726 C CG . PHE A 1 271 ? 6.432 44.262 -24.501 1.00 38.17 ? 269 PHE A CG 1 ATOM 1727 C CD1 . PHE A 1 271 ? 6.503 42.894 -24.250 1.00 39.73 ? 269 PHE A CD1 1 ATOM 1728 C CD2 . PHE A 1 271 ? 7.057 45.134 -23.618 1.00 39.29 ? 269 PHE A CD2 1 ATOM 1729 C CE1 . PHE A 1 271 ? 7.201 42.415 -23.149 1.00 40.55 ? 269 PHE A CE1 1 ATOM 1730 C CE2 . PHE A 1 271 ? 7.738 44.652 -22.504 1.00 41.15 ? 269 PHE A CE2 1 ATOM 1731 C CZ . PHE A 1 271 ? 7.803 43.296 -22.276 1.00 39.50 ? 269 PHE A CZ 1 ATOM 1732 N N . THR A 1 272 ? 6.502 43.387 -29.121 1.00 42.85 ? 270 THR A N 1 ATOM 1733 C CA . THR A 1 272 ? 5.872 42.793 -30.288 1.00 41.89 ? 270 THR A CA 1 ATOM 1734 C C . THR A 1 272 ? 6.294 41.353 -30.598 1.00 46.33 ? 270 THR A C 1 ATOM 1735 O O . THR A 1 272 ? 7.412 40.925 -30.284 1.00 45.33 ? 270 THR A O 1 ATOM 1736 C CB . THR A 1 272 ? 6.132 43.690 -31.522 1.00 41.15 ? 270 THR A CB 1 ATOM 1737 O OG1 . THR A 1 272 ? 7.532 43.759 -31.746 1.00 45.96 ? 270 THR A OG1 1 ATOM 1738 C CG2 . THR A 1 272 ? 5.530 45.103 -31.401 1.00 29.78 ? 270 THR A CG2 1 ATOM 1739 N N . ARG A 1 273 ? 5.401 40.632 -31.293 1.00 42.37 ? 271 ARG A N 1 ATOM 1740 C CA . ARG A 1 273 ? 5.678 39.314 -31.846 1.00 40.88 ? 271 ARG A CA 1 ATOM 1741 C C . ARG A 1 273 ? 6.802 39.525 -32.907 1.00 42.90 ? 271 ARG A C 1 ATOM 1742 O O . ARG A 1 273 ? 6.973 40.638 -33.413 1.00 41.45 ? 271 ARG A O 1 ATOM 1743 C CB . ARG A 1 273 ? 4.413 38.755 -32.534 1.00 39.12 ? 271 ARG A CB 1 ATOM 1744 C CG . ARG A 1 273 ? 3.187 38.579 -31.624 1.00 43.29 ? 271 ARG A CG 1 ATOM 1745 C CD . ARG A 1 273 ? 2.095 37.704 -32.246 1.00 39.34 ? 271 ARG A CD 1 ATOM 1746 N NE . ARG A 1 273 ? 2.415 36.277 -32.104 1.00 52.46 ? 271 ARG A NE 1 ATOM 1747 C CZ . ARG A 1 273 ? 1.559 35.275 -32.308 1.00 81.95 ? 271 ARG A CZ 1 ATOM 1748 N NH1 . ARG A 1 273 ? 0.300 35.525 -32.660 1.00 77.82 ? 271 ARG A NH1 1 ATOM 1749 N NH2 . ARG A 1 273 ? 1.950 34.014 -32.139 1.00 69.76 ? 271 ARG A NH2 1 ATOM 1750 N N . SER A 1 274 ? 7.570 38.473 -33.222 1.00 40.22 ? 272 SER A N 1 ATOM 1751 C CA . SER A 1 274 ? 8.662 38.524 -34.210 1.00 39.83 ? 272 SER A CA 1 ATOM 1752 C C . SER A 1 274 ? 8.250 39.132 -35.554 1.00 43.96 ? 272 SER A C 1 ATOM 1753 O O . SER A 1 274 ? 8.922 40.038 -36.062 1.00 42.60 ? 272 SER A O 1 ATOM 1754 C CB . SER A 1 274 ? 9.206 37.124 -34.457 1.00 41.46 ? 272 SER A CB 1 ATOM 1755 O OG . SER A 1 274 ? 9.435 36.491 -33.213 1.00 50.35 ? 272 SER A OG 1 ATOM 1756 N N . GLU A 1 275 ? 7.151 38.605 -36.132 1.00 41.14 ? 273 GLU A N 1 ATOM 1757 C CA . GLU A 1 275 ? 6.634 39.008 -37.437 1.00 40.81 ? 273 GLU A CA 1 ATOM 1758 C C . GLU A 1 275 ? 6.079 40.410 -37.424 1.00 43.53 ? 273 GLU A C 1 ATOM 1759 O O . GLU A 1 275 ? 6.036 41.032 -38.486 1.00 45.17 ? 273 GLU A O 1 ATOM 1760 C CB . GLU A 1 275 ? 5.630 37.999 -38.021 1.00 42.02 ? 273 GLU A CB 1 ATOM 1761 C CG . GLU A 1 275 ? 4.696 37.371 -37.002 1.00 54.36 ? 273 GLU A CG 1 ATOM 1762 C CD . GLU A 1 275 ? 5.322 36.270 -36.175 1.00 66.05 ? 273 GLU A CD 1 ATOM 1763 O OE1 . GLU A 1 275 ? 5.158 36.302 -34.935 1.00 54.65 ? 273 GLU A OE1 1 ATOM 1764 O OE2 . GLU A 1 275 ? 6.046 35.428 -36.755 1.00 59.27 ? 273 GLU A OE2 1 ATOM 1765 N N . ASP A 1 276 ? 5.712 40.933 -36.239 1.00 35.31 ? 274 ASP A N 1 ATOM 1766 C CA . ASP A 1 276 ? 5.214 42.295 -36.134 1.00 33.94 ? 274 ASP A CA 1 ATOM 1767 C C . ASP A 1 276 ? 6.378 43.253 -36.141 1.00 37.57 ? 274 ASP A C 1 ATOM 1768 O O . ASP A 1 276 ? 6.316 44.289 -36.794 1.00 36.21 ? 274 ASP A O 1 ATOM 1769 C CB . ASP A 1 276 ? 4.343 42.476 -34.878 1.00 35.89 ? 274 ASP A CB 1 ATOM 1770 C CG . ASP A 1 276 ? 2.946 41.848 -34.913 1.00 44.89 ? 274 ASP A CG 1 ATOM 1771 O OD1 . ASP A 1 276 ? 2.454 41.505 -36.028 1.00 44.62 ? 274 ASP A OD1 1 ATOM 1772 O OD2 . ASP A 1 276 ? 2.306 41.796 -33.862 1.00 53.64 ? 274 ASP A OD2 1 ATOM 1773 N N . ALA A 1 277 ? 7.443 42.918 -35.389 1.00 36.47 ? 275 ALA A N 1 ATOM 1774 C CA . ALA A 1 277 ? 8.683 43.703 -35.321 1.00 36.12 ? 275 ALA A CA 1 ATOM 1775 C C . ALA A 1 277 ? 9.258 43.768 -36.733 1.00 40.53 ? 275 ALA A C 1 ATOM 1776 O O . ALA A 1 277 ? 9.484 44.877 -37.247 1.00 38.83 ? 275 ALA A O 1 ATOM 1777 C CB . ALA A 1 277 ? 9.673 43.058 -34.361 1.00 36.50 ? 275 ALA A CB 1 ATOM 1778 N N . ARG A 1 278 ? 9.350 42.577 -37.408 1.00 38.37 ? 276 ARG A N 1 ATOM 1779 C CA . ARG A 1 278 ? 9.782 42.431 -38.806 1.00 38.07 ? 276 ARG A CA 1 ATOM 1780 C C . ARG A 1 278 ? 9.018 43.385 -39.724 1.00 42.45 ? 276 ARG A C 1 ATOM 1781 O O . ARG A 1 278 ? 9.639 44.139 -40.474 1.00 44.51 ? 276 ARG A O 1 ATOM 1782 C CB . ARG A 1 278 ? 9.570 40.994 -39.293 1.00 37.74 ? 276 ARG A CB 1 ATOM 1783 C CG . ARG A 1 278 ? 10.180 40.730 -40.669 1.00 45.65 ? 276 ARG A CG 1 ATOM 1784 C CD . ARG A 1 278 ? 9.662 39.468 -41.325 1.00 55.57 ? 276 ARG A CD 1 ATOM 1785 N NE . ARG A 1 278 ? 8.232 39.553 -41.634 1.00 63.29 ? 276 ARG A NE 1 ATOM 1786 C CZ . ARG A 1 278 ? 7.345 38.588 -41.408 1.00 70.47 ? 276 ARG A CZ 1 ATOM 1787 N NH1 . ARG A 1 278 ? 7.727 37.435 -40.871 1.00 46.14 ? 276 ARG A NH1 1 ATOM 1788 N NH2 . ARG A 1 278 ? 6.071 38.763 -41.728 1.00 62.98 ? 276 ARG A NH2 1 ATOM 1789 N N . GLU A 1 279 ? 7.686 43.370 -39.633 1.00 38.08 ? 277 GLU A N 1 ATOM 1790 C CA . GLU A 1 279 ? 6.798 44.171 -40.461 1.00 37.73 ? 277 GLU A CA 1 ATOM 1791 C C . GLU A 1 279 ? 6.862 45.670 -40.187 1.00 43.87 ? 277 GLU A C 1 ATOM 1792 O O . GLU A 1 279 ? 6.677 46.461 -41.116 1.00 44.71 ? 277 GLU A O 1 ATOM 1793 C CB . GLU A 1 279 ? 5.364 43.653 -40.376 1.00 38.62 ? 277 GLU A CB 1 ATOM 1794 C CG . GLU A 1 279 ? 5.126 42.366 -41.157 1.00 43.48 ? 277 GLU A CG 1 ATOM 1795 C CD . GLU A 1 279 ? 5.654 42.304 -42.580 1.00 65.34 ? 277 GLU A CD 1 ATOM 1796 O OE1 . GLU A 1 279 ? 6.341 41.309 -42.898 1.00 70.93 ? 277 GLU A OE1 1 ATOM 1797 O OE2 . GLU A 1 279 ? 5.393 43.239 -43.373 1.00 61.34 ? 277 GLU A OE2 1 ATOM 1798 N N . LEU A 1 280 ? 7.175 46.057 -38.952 1.00 40.94 ? 278 LEU A N 1 ATOM 1799 C CA . LEU A 1 280 ? 7.315 47.460 -38.541 1.00 40.86 ? 278 LEU A CA 1 ATOM 1800 C C . LEU A 1 280 ? 8.599 48.080 -39.103 1.00 42.66 ? 278 LEU A C 1 ATOM 1801 O O . LEU A 1 280 ? 8.608 49.256 -39.421 1.00 43.44 ? 278 LEU A O 1 ATOM 1802 C CB . LEU A 1 280 ? 7.363 47.550 -37.001 1.00 41.19 ? 278 LEU A CB 1 ATOM 1803 C CG . LEU A 1 280 ? 6.205 48.187 -36.255 1.00 45.38 ? 278 LEU A CG 1 ATOM 1804 C CD1 . LEU A 1 280 ? 6.546 48.267 -34.783 1.00 45.03 ? 278 LEU A CD1 1 ATOM 1805 C CD2 . LEU A 1 280 ? 5.920 49.601 -36.763 1.00 46.96 ? 278 LEU A CD2 1 ATOM 1806 N N . LEU A 1 281 ? 9.636 47.292 -39.233 1.00 37.94 ? 279 LEU A N 1 ATOM 1807 C CA . LEU A 1 281 ? 10.891 47.750 -39.741 1.00 37.90 ? 279 LEU A CA 1 ATOM 1808 C C . LEU A 1 281 ? 10.797 47.986 -41.221 1.00 43.67 ? 279 LEU A C 1 ATOM 1809 O O . LEU A 1 281 ? 11.244 48.971 -41.725 1.00 45.32 ? 279 LEU A O 1 ATOM 1810 C CB . LEU A 1 281 ? 11.939 46.701 -39.477 1.00 38.06 ? 279 LEU A CB 1 ATOM 1811 C CG . LEU A 1 281 ? 12.475 46.577 -38.069 1.00 41.84 ? 279 LEU A CG 1 ATOM 1812 C CD1 . LEU A 1 281 ? 13.320 45.344 -37.889 1.00 42.06 ? 279 LEU A CD1 1 ATOM 1813 C CD2 . LEU A 1 281 ? 13.283 47.790 -37.734 1.00 41.88 ? 279 LEU A CD2 1 ATOM 1814 N N . ALA A 1 282 ? 10.198 47.044 -41.906 1.00 39.05 ? 280 ALA A N 1 ATOM 1815 C CA . ALA A 1 282 ? 9.896 47.112 -43.341 1.00 37.01 ? 280 ALA A CA 1 ATOM 1816 C C . ALA A 1 282 ? 9.184 48.408 -43.670 1.00 42.64 ? 280 ALA A C 1 ATOM 1817 O O . ALA A 1 282 ? 9.644 49.133 -44.543 1.00 44.55 ? 280 ALA A O 1 ATOM 1818 C CB . ALA A 1 282 ? 9.020 45.945 -43.731 1.00 37.01 ? 280 ALA A CB 1 ATOM 1819 N N . ALA A 1 283 ? 8.101 48.742 -42.945 1.00 39.55 ? 281 ALA A N 1 ATOM 1820 C CA . ALA A 1 283 ? 7.366 50.001 -43.160 1.00 38.54 ? 281 ALA A CA 1 ATOM 1821 C C . ALA A 1 283 ? 8.275 51.198 -42.870 1.00 43.39 ? 281 ALA A C 1 ATOM 1822 O O . ALA A 1 283 ? 8.227 52.184 -43.600 1.00 43.37 ? 281 ALA A O 1 ATOM 1823 C CB . ALA A 1 283 ? 6.115 50.058 -42.288 1.00 37.95 ? 281 ALA A CB 1 ATOM 1824 N N . SER A 1 284 ? 9.150 51.072 -41.854 1.00 40.27 ? 282 SER A N 1 ATOM 1825 C CA . SER A 1 284 ? 10.067 52.128 -41.437 1.00 41.20 ? 282 SER A CA 1 ATOM 1826 C C . SER A 1 284 ? 11.092 52.393 -42.494 1.00 45.95 ? 282 SER A C 1 ATOM 1827 O O . SER A 1 284 ? 11.483 53.537 -42.716 1.00 45.54 ? 282 SER A O 1 ATOM 1828 C CB . SER A 1 284 ? 10.720 51.778 -40.107 1.00 45.30 ? 282 SER A CB 1 ATOM 1829 O OG . SER A 1 284 ? 9.695 51.742 -39.130 1.00 54.25 ? 282 SER A OG 1 ATOM 1830 N N . GLN A 1 285 ? 11.498 51.327 -43.167 1.00 43.80 ? 283 GLN A N 1 ATOM 1831 C CA . GLN A 1 285 ? 12.435 51.354 -44.265 1.00 43.67 ? 283 GLN A CA 1 ATOM 1832 C C . GLN A 1 285 ? 11.717 51.997 -45.430 1.00 47.41 ? 283 GLN A C 1 ATOM 1833 O O . GLN A 1 285 ? 12.227 52.955 -45.996 1.00 49.18 ? 283 GLN A O 1 ATOM 1834 C CB . GLN A 1 285 ? 12.900 49.920 -44.593 1.00 45.03 ? 283 GLN A CB 1 ATOM 1835 C CG . GLN A 1 285 ? 13.956 49.824 -45.691 1.00 56.46 ? 283 GLN A CG 1 ATOM 1836 C CD . GLN A 1 285 ? 15.212 50.575 -45.327 1.00 75.21 ? 283 GLN A CD 1 ATOM 1837 O OE1 . GLN A 1 285 ? 15.412 51.718 -45.754 1.00 65.26 ? 283 GLN A OE1 1 ATOM 1838 N NE2 . GLN A 1 285 ? 16.065 49.962 -44.503 1.00 74.95 ? 283 GLN A NE2 1 ATOM 1839 N N . ARG A 1 286 ? 10.492 51.537 -45.712 1.00 41.47 ? 284 ARG A N 1 ATOM 1840 C CA . ARG A 1 286 ? 9.667 52.019 -46.806 1.00 40.47 ? 284 ARG A CA 1 ATOM 1841 C C . ARG A 1 286 ? 9.421 53.514 -46.763 1.00 46.18 ? 284 ARG A C 1 ATOM 1842 O O . ARG A 1 286 ? 9.329 54.142 -47.811 1.00 47.00 ? 284 ARG A O 1 ATOM 1843 C CB . ARG A 1 286 ? 8.338 51.287 -46.793 1.00 36.70 ? 284 ARG A CB 1 ATOM 1844 C CG . ARG A 1 286 ? 8.194 50.292 -47.901 1.00 31.90 ? 284 ARG A CG 1 ATOM 1845 C CD . ARG A 1 286 ? 7.496 49.006 -47.487 1.00 39.09 ? 284 ARG A CD 1 ATOM 1846 N NE . ARG A 1 286 ? 6.252 49.194 -46.729 1.00 37.07 ? 284 ARG A NE 1 ATOM 1847 C CZ . ARG A 1 286 ? 5.727 48.246 -45.964 1.00 54.60 ? 284 ARG A CZ 1 ATOM 1848 N NH1 . ARG A 1 286 ? 6.318 47.063 -45.863 1.00 50.67 ? 284 ARG A NH1 1 ATOM 1849 N NH2 . ARG A 1 286 ? 4.606 48.467 -45.302 1.00 46.87 ? 284 ARG A NH2 1 ATOM 1850 N N . LEU A 1 287 ? 9.285 54.080 -45.571 1.00 43.29 ? 285 LEU A N 1 ATOM 1851 C CA . LEU A 1 287 ? 8.985 55.501 -45.412 1.00 43.03 ? 285 LEU A CA 1 ATOM 1852 C C . LEU A 1 287 ? 10.240 56.365 -45.147 1.00 46.85 ? 285 LEU A C 1 ATOM 1853 O O . LEU A 1 287 ? 10.118 57.579 -44.977 1.00 45.40 ? 285 LEU A O 1 ATOM 1854 C CB . LEU A 1 287 ? 7.942 55.688 -44.297 1.00 42.50 ? 285 LEU A CB 1 ATOM 1855 C CG . LEU A 1 287 ? 6.608 54.976 -44.461 1.00 48.23 ? 285 LEU A CG 1 ATOM 1856 C CD1 . LEU A 1 287 ? 5.784 55.108 -43.205 1.00 49.05 ? 285 LEU A CD1 1 ATOM 1857 C CD2 . LEU A 1 287 ? 5.790 55.548 -45.621 1.00 50.95 ? 285 LEU A CD2 1 ATOM 1858 N N . ASN A 1 288 ? 11.434 55.739 -45.150 1.00 44.34 ? 286 ASN A N 1 ATOM 1859 C CA . ASN A 1 288 ? 12.716 56.373 -44.803 1.00 46.14 ? 286 ASN A CA 1 ATOM 1860 C C . ASN A 1 288 ? 12.663 56.959 -43.351 1.00 52.33 ? 286 ASN A C 1 ATOM 1861 O O . ASN A 1 288 ? 13.289 57.983 -43.055 1.00 52.10 ? 286 ASN A O 1 ATOM 1862 C CB . ASN A 1 288 ? 13.194 57.407 -45.857 1.00 46.94 ? 286 ASN A CB 1 ATOM 1863 C CG . ASN A 1 288 ? 14.590 57.933 -45.605 1.00 64.07 ? 286 ASN A CG 1 ATOM 1864 O OD1 . ASN A 1 288 ? 15.440 57.236 -45.026 1.00 53.18 ? 286 ASN A OD1 1 ATOM 1865 N ND2 . ASN A 1 288 ? 14.825 59.213 -45.941 1.00 53.51 ? 286 ASN A ND2 1 ATOM 1866 N N . ALA A 1 289 ? 11.895 56.284 -42.459 1.00 48.81 ? 287 ALA A N 1 ATOM 1867 C CA . ALA A 1 289 ? 11.712 56.667 -41.069 1.00 48.91 ? 287 ALA A CA 1 ATOM 1868 C C . ALA A 1 289 ? 12.797 56.069 -40.194 1.00 53.94 ? 287 ALA A C 1 ATOM 1869 O O . ALA A 1 289 ? 13.118 54.891 -40.329 1.00 54.46 ? 287 ALA A O 1 ATOM 1870 C CB . ALA A 1 289 ? 10.347 56.217 -40.592 1.00 49.80 ? 287 ALA A CB 1 ATOM 1871 N N . SER A 1 290 ? 13.376 56.876 -39.304 1.00 51.48 ? 288 SER A N 1 ATOM 1872 C CA . SER A 1 290 ? 14.444 56.420 -38.401 1.00 51.41 ? 288 SER A CA 1 ATOM 1873 C C . SER A 1 290 ? 14.030 56.456 -36.943 1.00 52.90 ? 288 SER A C 1 ATOM 1874 O O . SER A 1 290 ? 13.438 57.439 -36.474 1.00 53.92 ? 288 SER A O 1 ATOM 1875 C CB . SER A 1 290 ? 15.731 57.218 -38.608 1.00 55.44 ? 288 SER A CB 1 ATOM 1876 O OG . SER A 1 290 ? 16.518 56.638 -39.636 1.00 67.28 ? 288 SER A OG 1 ATOM 1877 N N . PHE A 1 291 ? 14.348 55.377 -36.226 1.00 45.69 ? 289 PHE A N 1 ATOM 1878 C CA . PHE A 1 291 ? 14.041 55.253 -34.814 1.00 43.53 ? 289 PHE A CA 1 ATOM 1879 C C . PHE A 1 291 ? 15.104 54.477 -34.118 1.00 46.20 ? 289 PHE A C 1 ATOM 1880 O O . PHE A 1 291 ? 15.757 53.617 -34.703 1.00 45.79 ? 289 PHE A O 1 ATOM 1881 C CB . PHE A 1 291 ? 12.700 54.521 -34.601 1.00 44.94 ? 289 PHE A CB 1 ATOM 1882 C CG . PHE A 1 291 ? 11.490 55.161 -35.227 1.00 45.84 ? 289 PHE A CG 1 ATOM 1883 C CD1 . PHE A 1 291 ? 10.861 56.241 -34.621 1.00 47.67 ? 289 PHE A CD1 1 ATOM 1884 C CD2 . PHE A 1 291 ? 10.971 54.681 -36.422 1.00 46.84 ? 289 PHE A CD2 1 ATOM 1885 C CE1 . PHE A 1 291 ? 9.734 56.830 -35.203 1.00 47.76 ? 289 PHE A CE1 1 ATOM 1886 C CE2 . PHE A 1 291 ? 9.837 55.267 -36.998 1.00 49.41 ? 289 PHE A CE2 1 ATOM 1887 C CZ . PHE A 1 291 ? 9.230 56.340 -36.387 1.00 46.83 ? 289 PHE A CZ 1 ATOM 1888 N N . THR A 1 292 ? 15.239 54.754 -32.838 1.00 43.87 ? 290 THR A N 1 ATOM 1889 C CA . THR A 1 292 ? 16.045 54.013 -31.898 1.00 43.92 ? 290 THR A CA 1 ATOM 1890 C C . THR A 1 292 ? 15.041 53.046 -31.303 1.00 48.16 ? 290 THR A C 1 ATOM 1891 O O . THR A 1 292 ? 14.127 53.462 -30.591 1.00 48.46 ? 290 THR A O 1 ATOM 1892 C CB . THR A 1 292 ? 16.687 54.962 -30.883 1.00 50.74 ? 290 THR A CB 1 ATOM 1893 O OG1 . THR A 1 292 ? 17.637 55.736 -31.612 1.00 51.96 ? 290 THR A OG1 1 ATOM 1894 C CG2 . THR A 1 292 ? 17.379 54.215 -29.710 1.00 44.64 ? 290 THR A CG2 1 ATOM 1895 N N . TRP A 1 293 ? 15.148 51.777 -31.673 1.00 45.39 ? 291 TRP A N 1 ATOM 1896 C CA . TRP A 1 293 ? 14.217 50.770 -31.174 1.00 45.36 ? 291 TRP A CA 1 ATOM 1897 C C . TRP A 1 293 ? 14.776 50.133 -29.922 1.00 49.92 ? 291 TRP A C 1 ATOM 1898 O O . TRP A 1 293 ? 15.974 49.851 -29.855 1.00 49.87 ? 291 TRP A O 1 ATOM 1899 C CB . TRP A 1 293 ? 13.985 49.655 -32.194 1.00 43.76 ? 291 TRP A CB 1 ATOM 1900 C CG . TRP A 1 293 ? 13.760 50.104 -33.599 1.00 44.05 ? 291 TRP A CG 1 ATOM 1901 C CD1 . TRP A 1 293 ? 14.696 50.222 -34.580 1.00 46.67 ? 291 TRP A CD1 1 ATOM 1902 C CD2 . TRP A 1 293 ? 12.512 50.480 -34.182 1.00 43.73 ? 291 TRP A CD2 1 ATOM 1903 N NE1 . TRP A 1 293 ? 14.113 50.685 -35.732 1.00 46.53 ? 291 TRP A NE1 1 ATOM 1904 C CE2 . TRP A 1 293 ? 12.766 50.823 -35.527 1.00 47.59 ? 291 TRP A CE2 1 ATOM 1905 C CE3 . TRP A 1 293 ? 11.195 50.543 -33.706 1.00 44.53 ? 291 TRP A CE3 1 ATOM 1906 C CZ2 . TRP A 1 293 ? 11.748 51.182 -36.412 1.00 46.25 ? 291 TRP A CZ2 1 ATOM 1907 C CZ3 . TRP A 1 293 ? 10.196 50.951 -34.573 1.00 45.71 ? 291 TRP A CZ3 1 ATOM 1908 C CH2 . TRP A 1 293 ? 10.474 51.252 -35.913 1.00 45.95 ? 291 TRP A CH2 1 ATOM 1909 N N . VAL A 1 294 ? 13.892 49.920 -28.927 1.00 45.11 ? 292 VAL A N 1 ATOM 1910 C CA . VAL A 1 294 ? 14.151 49.214 -27.677 1.00 43.35 ? 292 VAL A CA 1 ATOM 1911 C C . VAL A 1 294 ? 13.052 48.160 -27.667 1.00 44.80 ? 292 VAL A C 1 ATOM 1912 O O . VAL A 1 294 ? 11.868 48.484 -27.586 1.00 44.48 ? 292 VAL A O 1 ATOM 1913 C CB . VAL A 1 294 ? 14.153 50.120 -26.431 1.00 46.75 ? 292 VAL A CB 1 ATOM 1914 C CG1 . VAL A 1 294 ? 14.619 49.341 -25.188 1.00 45.63 ? 292 VAL A CG1 1 ATOM 1915 C CG2 . VAL A 1 294 ? 15.028 51.350 -26.665 1.00 46.86 ? 292 VAL A CG2 1 ATOM 1916 N N . ALA A 1 295 ? 13.436 46.915 -27.856 1.00 40.88 ? 293 ALA A N 1 ATOM 1917 C CA . ALA A 1 295 ? 12.471 45.838 -28.024 1.00 40.22 ? 293 ALA A CA 1 ATOM 1918 C C . ALA A 1 295 ? 12.696 44.628 -27.154 1.00 42.93 ? 293 ALA A C 1 ATOM 1919 O O . ALA A 1 295 ? 13.818 44.335 -26.730 1.00 42.71 ? 293 ALA A O 1 ATOM 1920 C CB . ALA A 1 295 ? 12.415 45.426 -29.489 1.00 40.45 ? 293 ALA A CB 1 ATOM 1921 N N . SER A 1 296 ? 11.599 43.899 -26.946 1.00 37.64 ? 294 SER A N 1 ATOM 1922 C CA . SER A 1 296 ? 11.458 42.689 -26.140 1.00 36.45 ? 294 SER A CA 1 ATOM 1923 C C . SER A 1 296 ? 11.943 41.410 -26.834 1.00 40.66 ? 294 SER A C 1 ATOM 1924 O O . SER A 1 296 ? 12.383 41.441 -27.994 1.00 39.26 ? 294 SER A O 1 ATOM 1925 C CB . SER A 1 296 ? 9.999 42.538 -25.718 1.00 36.76 ? 294 SER A CB 1 ATOM 1926 O OG . SER A 1 296 ? 9.199 42.670 -26.885 1.00 43.27 ? 294 SER A OG 1 ATOM 1927 N N . ASP A 1 297 ? 11.766 40.262 -26.149 1.00 38.77 ? 295 ASP A N 1 ATOM 1928 C CA . ASP A 1 297 ? 12.240 38.967 -26.624 1.00 39.56 ? 295 ASP A CA 1 ATOM 1929 C C . ASP A 1 297 ? 11.612 38.498 -27.945 1.00 43.47 ? 295 ASP A C 1 ATOM 1930 O O . ASP A 1 297 ? 12.154 37.602 -28.587 1.00 40.86 ? 295 ASP A O 1 ATOM 1931 C CB . ASP A 1 297 ? 12.122 37.894 -25.523 1.00 41.49 ? 295 ASP A CB 1 ATOM 1932 C CG . ASP A 1 297 ? 10.721 37.484 -25.159 1.00 45.74 ? 295 ASP A CG 1 ATOM 1933 O OD1 . ASP A 1 297 ? 9.948 38.364 -24.694 1.00 44.36 ? 295 ASP A OD1 1 ATOM 1934 O OD2 . ASP A 1 297 ? 10.406 36.264 -25.289 1.00 45.42 ? 295 ASP A OD2 1 ATOM 1935 N N . GLY A 1 298 ? 10.495 39.107 -28.334 1.00 43.44 ? 296 GLY A N 1 ATOM 1936 C CA . GLY A 1 298 ? 9.806 38.793 -29.586 1.00 44.24 ? 296 GLY A CA 1 ATOM 1937 C C . GLY A 1 298 ? 10.682 39.119 -30.790 1.00 48.25 ? 296 GLY A C 1 ATOM 1938 O O . GLY A 1 298 ? 10.686 38.382 -31.776 1.00 48.26 ? 296 GLY A O 1 ATOM 1939 N N . TRP A 1 299 ? 11.464 40.213 -30.691 1.00 42.79 ? 297 TRP A N 1 ATOM 1940 C CA . TRP A 1 299 ? 12.450 40.622 -31.690 1.00 40.68 ? 297 TRP A CA 1 ATOM 1941 C C . TRP A 1 299 ? 13.766 39.886 -31.294 1.00 44.16 ? 297 TRP A C 1 ATOM 1942 O O . TRP A 1 299 ? 14.384 39.259 -32.149 1.00 41.81 ? 297 TRP A O 1 ATOM 1943 C CB . TRP A 1 299 ? 12.598 42.178 -31.688 1.00 37.81 ? 297 TRP A CB 1 ATOM 1944 C CG . TRP A 1 299 ? 13.640 42.772 -32.608 1.00 37.98 ? 297 TRP A CG 1 ATOM 1945 C CD1 . TRP A 1 299 ? 14.782 42.172 -33.061 1.00 40.37 ? 297 TRP A CD1 1 ATOM 1946 C CD2 . TRP A 1 299 ? 13.714 44.140 -33.042 1.00 37.70 ? 297 TRP A CD2 1 ATOM 1947 N NE1 . TRP A 1 299 ? 15.532 43.064 -33.779 1.00 39.26 ? 297 TRP A NE1 1 ATOM 1948 C CE2 . TRP A 1 299 ? 14.904 44.279 -33.785 1.00 40.64 ? 297 TRP A CE2 1 ATOM 1949 C CE3 . TRP A 1 299 ? 12.904 45.271 -32.848 1.00 38.88 ? 297 TRP A CE3 1 ATOM 1950 C CZ2 . TRP A 1 299 ? 15.294 45.494 -34.345 1.00 39.92 ? 297 TRP A CZ2 1 ATOM 1951 C CZ3 . TRP A 1 299 ? 13.269 46.462 -33.439 1.00 40.25 ? 297 TRP A CZ3 1 ATOM 1952 C CH2 . TRP A 1 299 ? 14.448 46.568 -34.182 1.00 40.91 ? 297 TRP A CH2 1 ATOM 1953 N N . GLY A 1 300 ? 14.130 39.959 -29.998 1.00 42.27 ? 298 GLY A N 1 ATOM 1954 C CA . GLY A 1 300 ? 15.321 39.360 -29.393 1.00 41.75 ? 298 GLY A CA 1 ATOM 1955 C C . GLY A 1 300 ? 16.590 39.615 -30.169 1.00 45.45 ? 298 GLY A C 1 ATOM 1956 O O . GLY A 1 300 ? 16.858 40.748 -30.548 1.00 46.20 ? 298 GLY A O 1 ATOM 1957 N N . ALA A 1 301 ? 17.347 38.554 -30.459 1.00 42.34 ? 299 ALA A N 1 ATOM 1958 C CA . ALA A 1 301 ? 18.561 38.602 -31.286 1.00 41.82 ? 299 ALA A CA 1 ATOM 1959 C C . ALA A 1 301 ? 18.277 37.799 -32.526 1.00 46.09 ? 299 ALA A C 1 ATOM 1960 O O . ALA A 1 301 ? 19.159 37.081 -32.997 1.00 46.53 ? 299 ALA A O 1 ATOM 1961 C CB . ALA A 1 301 ? 19.766 38.009 -30.539 1.00 42.27 ? 299 ALA A CB 1 ATOM 1962 N N . LEU A 1 302 ? 17.030 37.873 -33.038 1.00 42.68 ? 300 LEU A N 1 ATOM 1963 C CA . LEU A 1 302 ? 16.635 37.105 -34.217 1.00 42.47 ? 300 LEU A CA 1 ATOM 1964 C C . LEU A 1 302 ? 17.039 37.811 -35.469 1.00 48.32 ? 300 LEU A C 1 ATOM 1965 O O . LEU A 1 302 ? 16.778 39.000 -35.598 1.00 48.11 ? 300 LEU A O 1 ATOM 1966 C CB . LEU A 1 302 ? 15.113 36.846 -34.273 1.00 41.75 ? 300 LEU A CB 1 ATOM 1967 C CG . LEU A 1 302 ? 14.452 36.038 -33.165 1.00 44.94 ? 300 LEU A CG 1 ATOM 1968 C CD1 . LEU A 1 302 ? 12.914 36.075 -33.307 1.00 44.17 ? 300 LEU A CD1 1 ATOM 1969 C CD2 . LEU A 1 302 ? 14.950 34.621 -33.143 1.00 45.14 ? 300 LEU A CD2 1 ATOM 1970 N N . GLU A 1 303 ? 17.591 37.080 -36.429 1.00 47.16 ? 301 GLU A N 1 ATOM 1971 C CA . GLU A 1 303 ? 17.934 37.653 -37.740 1.00 48.10 ? 301 GLU A CA 1 ATOM 1972 C C . GLU A 1 303 ? 16.684 37.719 -38.633 1.00 51.53 ? 301 GLU A C 1 ATOM 1973 O O . GLU A 1 303 ? 16.594 38.599 -39.496 1.00 52.21 ? 301 GLU A O 1 ATOM 1974 C CB . GLU A 1 303 ? 19.079 36.880 -38.406 1.00 50.21 ? 301 GLU A CB 1 ATOM 1975 C CG . GLU A 1 303 ? 20.356 36.862 -37.570 1.00 66.12 ? 301 GLU A CG 1 ATOM 1976 C CD . GLU A 1 303 ? 21.653 37.025 -38.338 1.00 98.31 ? 301 GLU A CD 1 ATOM 1977 O OE1 . GLU A 1 303 ? 21.951 36.169 -39.204 1.00 110.78 ? 301 GLU A OE1 1 ATOM 1978 O OE2 . GLU A 1 303 ? 22.392 37.993 -38.047 1.00 90.58 ? 301 GLU A OE2 1 ATOM 1979 N N . SER A 1 304 ? 15.690 36.820 -38.379 1.00 46.41 ? 302 SER A N 1 ATOM 1980 C CA . SER A 1 304 ? 14.380 36.748 -39.043 1.00 45.45 ? 302 SER A CA 1 ATOM 1981 C C . SER A 1 304 ? 13.780 38.156 -39.136 1.00 52.26 ? 302 SER A C 1 ATOM 1982 O O . SER A 1 304 ? 13.236 38.552 -40.179 1.00 55.76 ? 302 SER A O 1 ATOM 1983 C CB . SER A 1 304 ? 13.433 35.811 -38.291 1.00 20.00 ? 302 SER A CB 1 ATOM 1984 O OG . SER A 1 304 ? 13.166 36.294 -36.987 1.00 20.00 ? 302 SER A OG 1 ATOM 1985 N N . VAL A 1 305 ? 13.841 38.878 -38.003 1.00 43.98 ? 303 VAL A N 1 ATOM 1986 C CA . VAL A 1 305 ? 13.252 40.178 -37.794 1.00 41.75 ? 303 VAL A CA 1 ATOM 1987 C C . VAL A 1 305 ? 13.906 41.289 -38.634 1.00 45.81 ? 303 VAL A C 1 ATOM 1988 O O . VAL A 1 305 ? 13.195 42.134 -39.198 1.00 46.30 ? 303 VAL A O 1 ATOM 1989 C CB . VAL A 1 305 ? 13.257 40.485 -36.266 1.00 43.22 ? 303 VAL A CB 1 ATOM 1990 C CG1 . VAL A 1 305 ? 12.858 41.936 -35.970 1.00 43.03 ? 303 VAL A CG1 1 ATOM 1991 C CG2 . VAL A 1 305 ? 12.374 39.503 -35.501 1.00 41.39 ? 303 VAL A CG2 1 ATOM 1992 N N . VAL A 1 306 ? 15.229 41.286 -38.714 1.00 41.63 ? 304 VAL A N 1 ATOM 1993 C CA . VAL A 1 306 ? 15.999 42.353 -39.351 1.00 42.42 ? 304 VAL A CA 1 ATOM 1994 C C . VAL A 1 306 ? 16.357 42.103 -40.801 1.00 50.39 ? 304 VAL A C 1 ATOM 1995 O O . VAL A 1 306 ? 16.741 43.052 -41.501 1.00 50.11 ? 304 VAL A O 1 ATOM 1996 C CB . VAL A 1 306 ? 17.267 42.685 -38.517 1.00 46.34 ? 304 VAL A CB 1 ATOM 1997 C CG1 . VAL A 1 306 ? 16.896 43.405 -37.218 1.00 45.61 ? 304 VAL A CG1 1 ATOM 1998 C CG2 . VAL A 1 306 ? 18.100 41.433 -38.226 1.00 46.01 ? 304 VAL A CG2 1 ATOM 1999 N N . ALA A 1 307 ? 16.273 40.833 -41.254 1.00 49.61 ? 305 ALA A N 1 ATOM 2000 C CA . ALA A 1 307 ? 16.605 40.465 -42.638 1.00 49.33 ? 305 ALA A CA 1 ATOM 2001 C C . ALA A 1 307 ? 15.781 41.319 -43.596 1.00 52.62 ? 305 ALA A C 1 ATOM 2002 O O . ALA A 1 307 ? 14.562 41.389 -43.482 1.00 50.98 ? 305 ALA A O 1 ATOM 2003 C CB . ALA A 1 307 ? 16.328 38.983 -42.873 1.00 49.83 ? 305 ALA A CB 1 ATOM 2004 N N . GLY A 1 308 ? 16.472 42.035 -44.460 1.00 51.14 ? 306 GLY A N 1 ATOM 2005 C CA . GLY A 1 308 ? 15.851 42.930 -45.436 1.00 50.82 ? 306 GLY A CA 1 ATOM 2006 C C . GLY A 1 308 ? 15.806 44.377 -44.982 1.00 53.59 ? 306 GLY A C 1 ATOM 2007 O O . GLY A 1 308 ? 15.834 45.280 -45.816 1.00 53.83 ? 306 GLY A O 1 ATOM 2008 N N . SER A 1 309 ? 15.764 44.616 -43.653 1.00 48.25 ? 307 SER A N 1 ATOM 2009 C CA . SER A 1 309 ? 15.653 45.955 -43.089 1.00 47.13 ? 307 SER A CA 1 ATOM 2010 C C . SER A 1 309 ? 16.782 46.275 -42.122 1.00 52.23 ? 307 SER A C 1 ATOM 2011 O O . SER A 1 309 ? 16.557 46.976 -41.133 1.00 52.22 ? 307 SER A O 1 ATOM 2012 C CB . SER A 1 309 ? 14.293 46.123 -42.416 1.00 49.95 ? 307 SER A CB 1 ATOM 2013 O OG . SER A 1 309 ? 13.225 46.048 -43.348 1.00 59.61 ? 307 SER A OG 1 ATOM 2014 N N . GLU A 1 310 ? 18.019 45.822 -42.454 1.00 49.07 ? 308 GLU A N 1 ATOM 2015 C CA . GLU A 1 310 ? 19.246 46.008 -41.669 1.00 48.12 ? 308 GLU A CA 1 ATOM 2016 C C . GLU A 1 310 ? 19.505 47.461 -41.355 1.00 53.93 ? 308 GLU A C 1 ATOM 2017 O O . GLU A 1 310 ? 19.799 47.798 -40.206 1.00 56.05 ? 308 GLU A O 1 ATOM 2018 C CB . GLU A 1 310 ? 20.459 45.386 -42.368 1.00 48.93 ? 308 GLU A CB 1 ATOM 2019 C CG . GLU A 1 310 ? 20.390 43.882 -42.600 1.00 53.00 ? 308 GLU A CG 1 ATOM 2020 C CD . GLU A 1 310 ? 19.573 43.405 -43.791 1.00 66.49 ? 308 GLU A CD 1 ATOM 2021 O OE1 . GLU A 1 310 ? 19.139 44.251 -44.610 1.00 42.25 ? 308 GLU A OE1 1 ATOM 2022 O OE2 . GLU A 1 310 ? 19.347 42.176 -43.891 1.00 63.75 ? 308 GLU A OE2 1 ATOM 2023 N N . GLY A 1 311 ? 19.335 48.317 -42.347 1.00 50.08 ? 309 GLY A N 1 ATOM 2024 C CA . GLY A 1 311 ? 19.527 49.753 -42.183 1.00 50.25 ? 309 GLY A CA 1 ATOM 2025 C C . GLY A 1 311 ? 18.543 50.379 -41.215 1.00 55.02 ? 309 GLY A C 1 ATOM 2026 O O . GLY A 1 311 ? 18.945 51.139 -40.332 1.00 56.13 ? 309 GLY A O 1 ATOM 2027 N N . ALA A 1 312 ? 17.250 50.043 -41.356 1.00 50.53 ? 310 ALA A N 1 ATOM 2028 C CA . ALA A 1 312 ? 16.172 50.560 -40.503 1.00 49.32 ? 310 ALA A CA 1 ATOM 2029 C C . ALA A 1 312 ? 16.328 50.140 -39.025 1.00 52.85 ? 310 ALA A C 1 ATOM 2030 O O . ALA A 1 312 ? 15.916 50.882 -38.130 1.00 52.91 ? 310 ALA A O 1 ATOM 2031 C CB . ALA A 1 312 ? 14.830 50.091 -41.039 1.00 49.73 ? 310 ALA A CB 1 ATOM 2032 N N . ALA A 1 313 ? 16.932 48.961 -38.790 1.00 48.05 ? 311 ALA A N 1 ATOM 2033 C CA . ALA A 1 313 ? 17.142 48.327 -37.498 1.00 47.74 ? 311 ALA A CA 1 ATOM 2034 C C . ALA A 1 313 ? 18.415 48.749 -36.787 1.00 55.74 ? 311 ALA A C 1 ATOM 2035 O O . ALA A 1 313 ? 18.471 48.676 -35.560 1.00 55.35 ? 311 ALA A O 1 ATOM 2036 C CB . ALA A 1 313 ? 17.166 46.831 -37.687 1.00 48.00 ? 311 ALA A CB 1 ATOM 2037 N N . GLU A 1 314 ? 19.468 49.107 -37.548 1.00 54.59 ? 312 GLU A N 1 ATOM 2038 C CA . GLU A 1 314 ? 20.773 49.499 -37.019 1.00 54.41 ? 312 GLU A CA 1 ATOM 2039 C C . GLU A 1 314 ? 20.687 50.458 -35.819 1.00 57.33 ? 312 GLU A C 1 ATOM 2040 O O . GLU A 1 314 ? 19.962 51.458 -35.887 1.00 57.84 ? 312 GLU A O 1 ATOM 2041 C CB . GLU A 1 314 ? 21.630 50.087 -38.139 1.00 56.28 ? 312 GLU A CB 1 ATOM 2042 C CG . GLU A 1 314 ? 23.129 50.048 -37.857 1.00 68.91 ? 312 GLU A CG 1 ATOM 2043 C CD . GLU A 1 314 ? 24.014 50.818 -38.818 1.00 80.09 ? 312 GLU A CD 1 ATOM 2044 O OE1 . GLU A 1 314 ? 23.677 50.901 -40.024 1.00 74.83 ? 312 GLU A OE1 1 ATOM 2045 O OE2 . GLU A 1 314 ? 25.071 51.311 -38.363 1.00 68.43 ? 312 GLU A OE2 1 ATOM 2046 N N . GLY A 1 315 ? 21.397 50.102 -34.739 1.00 51.92 ? 313 GLY A N 1 ATOM 2047 C CA . GLY A 1 315 ? 21.468 50.858 -33.495 1.00 51.31 ? 313 GLY A CA 1 ATOM 2048 C C . GLY A 1 315 ? 20.419 50.481 -32.461 1.00 56.58 ? 313 GLY A C 1 ATOM 2049 O O . GLY A 1 315 ? 20.337 51.111 -31.398 1.00 56.91 ? 313 GLY A O 1 ATOM 2050 N N . ALA A 1 316 ? 19.603 49.450 -32.747 1.00 52.47 ? 314 ALA A N 1 ATOM 2051 C CA . ALA A 1 316 ? 18.547 49.049 -31.818 1.00 51.25 ? 314 ALA A CA 1 ATOM 2052 C C . ALA A 1 316 ? 19.101 48.429 -30.539 1.00 53.03 ? 314 ALA A C 1 ATOM 2053 O O . ALA A 1 316 ? 20.220 47.931 -30.536 1.00 53.59 ? 314 ALA A O 1 ATOM 2054 C CB . ALA A 1 316 ? 17.589 48.085 -32.495 1.00 51.58 ? 314 ALA A CB 1 ATOM 2055 N N . ILE A 1 317 ? 18.325 48.496 -29.457 1.00 47.51 ? 315 ILE A N 1 ATOM 2056 C CA . ILE A 1 317 ? 18.613 47.826 -28.195 1.00 47.65 ? 315 ILE A CA 1 ATOM 2057 C C . ILE A 1 317 ? 17.545 46.746 -28.063 1.00 50.02 ? 315 ILE A C 1 ATOM 2058 O O . ILE A 1 317 ? 16.369 47.060 -28.194 1.00 48.00 ? 315 ILE A O 1 ATOM 2059 C CB . ILE A 1 317 ? 18.648 48.767 -26.975 1.00 50.81 ? 315 ILE A CB 1 ATOM 2060 C CG1 . ILE A 1 317 ? 19.897 49.660 -27.023 1.00 51.21 ? 315 ILE A CG1 1 ATOM 2061 C CG2 . ILE A 1 317 ? 18.606 47.955 -25.674 1.00 50.54 ? 315 ILE A CG2 1 ATOM 2062 C CD1 . ILE A 1 317 ? 19.775 50.886 -26.217 1.00 54.99 ? 315 ILE A CD1 1 ATOM 2063 N N . THR A 1 318 ? 17.948 45.471 -27.919 1.00 46.63 ? 316 THR A N 1 ATOM 2064 C CA . THR A 1 318 ? 16.960 44.391 -27.826 1.00 46.06 ? 316 THR A CA 1 ATOM 2065 C C . THR A 1 318 ? 17.225 43.452 -26.686 1.00 48.34 ? 316 THR A C 1 ATOM 2066 O O . THR A 1 318 ? 18.377 43.190 -26.370 1.00 48.01 ? 316 THR A O 1 ATOM 2067 C CB . THR A 1 318 ? 16.812 43.598 -29.128 1.00 46.39 ? 316 THR A CB 1 ATOM 2068 O OG1 . THR A 1 318 ? 18.000 42.847 -29.346 1.00 42.03 ? 316 THR A OG1 1 ATOM 2069 C CG2 . THR A 1 318 ? 16.447 44.457 -30.327 1.00 39.42 ? 316 THR A CG2 1 ATOM 2070 N N . ILE A 1 319 ? 16.149 42.928 -26.096 1.00 44.69 ? 317 ILE A N 1 ATOM 2071 C CA . ILE A 1 319 ? 16.206 41.983 -24.994 1.00 46.05 ? 317 ILE A CA 1 ATOM 2072 C C . ILE A 1 319 ? 15.955 40.541 -25.476 1.00 50.49 ? 317 ILE A C 1 ATOM 2073 O O . ILE A 1 319 ? 15.169 40.275 -26.391 1.00 48.29 ? 317 ILE A O 1 ATOM 2074 C CB . ILE A 1 319 ? 15.240 42.334 -23.813 1.00 50.36 ? 317 ILE A CB 1 ATOM 2075 C CG1 . ILE A 1 319 ? 15.167 43.868 -23.465 1.00 51.15 ? 317 ILE A CG1 1 ATOM 2076 C CG2 . ILE A 1 319 ? 15.559 41.505 -22.584 1.00 51.95 ? 317 ILE A CG2 1 ATOM 2077 C CD1 . ILE A 1 319 ? 16.344 44.531 -22.847 1.00 55.49 ? 317 ILE A CD1 1 ATOM 2078 N N . GLU A 1 320 ? 16.611 39.615 -24.796 1.00 48.21 ? 318 GLU A N 1 ATOM 2079 C CA . GLU A 1 320 ? 16.479 38.185 -24.965 1.00 47.26 ? 318 GLU A CA 1 ATOM 2080 C C . GLU A 1 320 ? 16.670 37.628 -23.567 1.00 51.80 ? 318 GLU A C 1 ATOM 2081 O O . GLU A 1 320 ? 17.529 38.118 -22.834 1.00 51.41 ? 318 GLU A O 1 ATOM 2082 C CB . GLU A 1 320 ? 17.543 37.672 -25.922 1.00 48.27 ? 318 GLU A CB 1 ATOM 2083 C CG . GLU A 1 320 ? 17.023 36.555 -26.798 1.00 59.02 ? 318 GLU A CG 1 ATOM 2084 C CD . GLU A 1 320 ? 18.055 35.922 -27.704 1.00 75.07 ? 318 GLU A CD 1 ATOM 2085 O OE1 . GLU A 1 320 ? 19.144 35.558 -27.193 1.00 55.08 ? 318 GLU A OE1 1 ATOM 2086 O OE2 . GLU A 1 320 ? 17.751 35.739 -28.910 1.00 62.77 ? 318 GLU A OE2 1 ATOM 2087 N N . LEU A 1 321 ? 15.821 36.687 -23.149 1.00 49.56 ? 319 LEU A N 1 ATOM 2088 C CA . LEU A 1 321 ? 15.936 36.079 -21.813 1.00 49.89 ? 319 LEU A CA 1 ATOM 2089 C C . LEU A 1 321 ? 17.331 35.378 -21.722 1.00 56.96 ? 319 LEU A C 1 ATOM 2090 O O . LEU A 1 321 ? 17.843 34.874 -22.742 1.00 56.44 ? 319 LEU A O 1 ATOM 2091 C CB . LEU A 1 321 ? 14.774 35.085 -21.589 1.00 49.03 ? 319 LEU A CB 1 ATOM 2092 C CG . LEU A 1 321 ? 13.427 35.636 -21.062 1.00 52.02 ? 319 LEU A CG 1 ATOM 2093 C CD1 . LEU A 1 321 ? 12.820 36.706 -21.958 1.00 51.93 ? 319 LEU A CD1 1 ATOM 2094 C CD2 . LEU A 1 321 ? 12.425 34.572 -21.009 1.00 51.76 ? 319 LEU A CD2 1 ATOM 2095 N N . ALA A 1 322 ? 17.988 35.460 -20.547 1.00 54.00 ? 320 ALA A N 1 ATOM 2096 C CA . ALA A 1 322 ? 19.338 34.902 -20.394 1.00 53.76 ? 320 ALA A CA 1 ATOM 2097 C C . ALA A 1 322 ? 19.375 33.373 -20.448 1.00 57.72 ? 320 ALA A C 1 ATOM 2098 O O . ALA A 1 322 ? 18.802 32.687 -19.597 1.00 58.09 ? 320 ALA A O 1 ATOM 2099 C CB . ALA A 1 322 ? 20.013 35.431 -19.135 1.00 54.42 ? 320 ALA A CB 1 ATOM 2100 N N . SER A 1 323 ? 19.991 32.854 -21.510 1.00 53.53 ? 321 SER A N 1 ATOM 2101 C CA . SER A 1 323 ? 20.123 31.429 -21.748 1.00 52.73 ? 321 SER A CA 1 ATOM 2102 C C . SER A 1 323 ? 21.490 31.110 -22.297 1.00 56.37 ? 321 SER A C 1 ATOM 2103 O O . SER A 1 323 ? 22.185 31.971 -22.839 1.00 55.50 ? 321 SER A O 1 ATOM 2104 C CB . SER A 1 323 ? 19.047 30.939 -22.710 1.00 55.53 ? 321 SER A CB 1 ATOM 2105 O OG . SER A 1 323 ? 19.187 31.578 -23.969 1.00 64.48 ? 321 SER A OG 1 ATOM 2106 N N . TYR A 1 324 ? 21.865 29.859 -22.149 1.00 54.62 ? 322 TYR A N 1 ATOM 2107 C CA . TYR A 1 324 ? 23.129 29.309 -22.600 1.00 55.59 ? 322 TYR A CA 1 ATOM 2108 C C . TYR A 1 324 ? 22.836 28.155 -23.547 1.00 66.10 ? 322 TYR A C 1 ATOM 2109 O O . TYR A 1 324 ? 21.758 27.554 -23.460 1.00 66.61 ? 322 TYR A O 1 ATOM 2110 C CB . TYR A 1 324 ? 23.994 28.845 -21.395 1.00 54.97 ? 322 TYR A CB 1 ATOM 2111 C CG . TYR A 1 324 ? 23.307 27.936 -20.401 1.00 54.03 ? 322 TYR A CG 1 ATOM 2112 C CD1 . TYR A 1 324 ? 22.976 26.623 -20.734 1.00 55.60 ? 322 TYR A CD1 1 ATOM 2113 C CD2 . TYR A 1 324 ? 23.036 28.367 -19.111 1.00 55.03 ? 322 TYR A CD2 1 ATOM 2114 C CE1 . TYR A 1 324 ? 22.359 25.776 -19.816 1.00 56.85 ? 322 TYR A CE1 1 ATOM 2115 C CE2 . TYR A 1 324 ? 22.454 27.517 -18.170 1.00 56.27 ? 322 TYR A CE2 1 ATOM 2116 C CZ . TYR A 1 324 ? 22.092 26.232 -18.533 1.00 64.65 ? 322 TYR A CZ 1 ATOM 2117 O OH . TYR A 1 324 ? 21.466 25.429 -17.612 1.00 66.46 ? 322 TYR A OH 1 ATOM 2118 N N . PRO A 1 325 ? 23.754 27.793 -24.453 1.00 67.60 ? 323 PRO A N 1 ATOM 2119 C CA . PRO A 1 325 ? 23.467 26.646 -25.317 1.00 68.83 ? 323 PRO A CA 1 ATOM 2120 C C . PRO A 1 325 ? 23.704 25.337 -24.554 1.00 74.66 ? 323 PRO A C 1 ATOM 2121 O O . PRO A 1 325 ? 24.707 25.207 -23.837 1.00 73.82 ? 323 PRO A O 1 ATOM 2122 C CB . PRO A 1 325 ? 24.417 26.848 -26.507 1.00 70.48 ? 323 PRO A CB 1 ATOM 2123 C CG . PRO A 1 325 ? 25.570 27.602 -25.959 1.00 74.74 ? 323 PRO A CG 1 ATOM 2124 C CD . PRO A 1 325 ? 25.100 28.350 -24.719 1.00 70.25 ? 323 PRO A CD 1 ATOM 2125 N N . ILE A 1 326 ? 22.754 24.391 -24.668 1.00 72.57 ? 324 ILE A N 1 ATOM 2126 C CA . ILE A 1 326 ? 22.872 23.097 -24.002 1.00 72.84 ? 324 ILE A CA 1 ATOM 2127 C C . ILE A 1 326 ? 23.770 22.168 -24.826 1.00 78.16 ? 324 ILE A C 1 ATOM 2128 O O . ILE A 1 326 ? 23.577 21.978 -26.034 1.00 77.86 ? 324 ILE A O 1 ATOM 2129 C CB . ILE A 1 326 ? 21.498 22.515 -23.600 1.00 75.85 ? 324 ILE A CB 1 ATOM 2130 C CG1 . ILE A 1 326 ? 21.192 23.001 -22.166 1.00 76.93 ? 324 ILE A CG1 1 ATOM 2131 C CG2 . ILE A 1 326 ? 21.446 20.973 -23.708 1.00 76.25 ? 324 ILE A CG2 1 ATOM 2132 C CD1 . ILE A 1 326 ? 19.819 22.804 -21.638 1.00 89.03 ? 324 ILE A CD1 1 ATOM 2133 N N . SER A 1 327 ? 24.789 21.647 -24.136 1.00 75.79 ? 325 SER A N 1 ATOM 2134 C CA . SER A 1 327 ? 25.880 20.791 -24.616 1.00 75.82 ? 325 SER A CA 1 ATOM 2135 C C . SER A 1 327 ? 25.501 19.654 -25.604 1.00 75.98 ? 325 SER A C 1 ATOM 2136 O O . SER A 1 327 ? 25.752 19.770 -26.808 1.00 75.44 ? 325 SER A O 1 ATOM 2137 C CB . SER A 1 327 ? 26.630 20.203 -23.418 1.00 80.99 ? 325 SER A CB 1 ATOM 2138 O OG . SER A 1 327 ? 25.790 19.408 -22.590 1.00 87.84 ? 325 SER A OG 1 ATOM 2139 N N . ASP A 1 328 ? 24.937 18.560 -25.073 1.00 69.55 ? 326 ASP A N 1 ATOM 2140 C CA . ASP A 1 328 ? 24.617 17.318 -25.774 1.00 68.46 ? 326 ASP A CA 1 ATOM 2141 C C . ASP A 1 328 ? 23.427 17.384 -26.749 1.00 69.18 ? 326 ASP A C 1 ATOM 2142 O O . ASP A 1 328 ? 23.258 16.448 -27.530 1.00 68.87 ? 326 ASP A O 1 ATOM 2143 C CB . ASP A 1 328 ? 24.406 16.191 -24.742 1.00 70.56 ? 326 ASP A CB 1 ATOM 2144 C CG . ASP A 1 328 ? 25.562 16.037 -23.763 1.00 82.93 ? 326 ASP A CG 1 ATOM 2145 O OD1 . ASP A 1 328 ? 26.710 15.814 -24.228 1.00 85.38 ? 326 ASP A OD1 1 ATOM 2146 O OD2 . ASP A 1 328 ? 25.326 16.164 -22.531 1.00 85.26 ? 326 ASP A OD2 1 ATOM 2147 N N . PHE A 1 329 ? 22.614 18.469 -26.713 1.00 62.58 ? 327 PHE A N 1 ATOM 2148 C CA . PHE A 1 329 ? 21.457 18.622 -27.601 1.00 60.16 ? 327 PHE A CA 1 ATOM 2149 C C . PHE A 1 329 ? 21.850 18.847 -29.072 1.00 64.54 ? 327 PHE A C 1 ATOM 2150 O O . PHE A 1 329 ? 21.213 18.254 -29.953 1.00 64.52 ? 327 PHE A O 1 ATOM 2151 C CB . PHE A 1 329 ? 20.472 19.712 -27.111 1.00 60.28 ? 327 PHE A CB 1 ATOM 2152 C CG . PHE A 1 329 ? 19.286 19.904 -28.034 1.00 59.61 ? 327 PHE A CG 1 ATOM 2153 C CD1 . PHE A 1 329 ? 18.338 18.897 -28.196 1.00 60.44 ? 327 PHE A CD1 1 ATOM 2154 C CD2 . PHE A 1 329 ? 19.165 21.052 -28.803 1.00 59.74 ? 327 PHE A CD2 1 ATOM 2155 C CE1 . PHE A 1 329 ? 17.276 19.051 -29.082 1.00 60.05 ? 327 PHE A CE1 1 ATOM 2156 C CE2 . PHE A 1 329 ? 18.093 21.208 -29.680 1.00 61.78 ? 327 PHE A CE2 1 ATOM 2157 C CZ . PHE A 1 329 ? 17.145 20.214 -29.795 1.00 59.33 ? 327 PHE A CZ 1 ATOM 2158 N N . ALA A 1 330 ? 22.856 19.722 -29.341 1.00 59.75 ? 328 ALA A N 1 ATOM 2159 C CA . ALA A 1 330 ? 23.323 20.009 -30.702 1.00 59.80 ? 328 ALA A CA 1 ATOM 2160 C C . ALA A 1 330 ? 23.714 18.704 -31.397 1.00 66.12 ? 328 ALA A C 1 ATOM 2161 O O . ALA A 1 330 ? 23.212 18.398 -32.488 1.00 67.41 ? 328 ALA A O 1 ATOM 2162 C CB . ALA A 1 330 ? 24.512 20.957 -30.667 1.00 60.40 ? 328 ALA A CB 1 ATOM 2163 N N . SER A 1 331 ? 24.538 17.897 -30.713 1.00 61.98 ? 329 SER A N 1 ATOM 2164 C CA . SER A 1 331 ? 25.000 16.599 -31.185 1.00 61.59 ? 329 SER A CA 1 ATOM 2165 C C . SER A 1 331 ? 23.809 15.655 -31.386 1.00 63.78 ? 329 SER A C 1 ATOM 2166 O O . SER A 1 331 ? 23.725 15.016 -32.437 1.00 64.43 ? 329 SER A O 1 ATOM 2167 C CB . SER A 1 331 ? 26.021 16.024 -30.209 1.00 65.88 ? 329 SER A CB 1 ATOM 2168 O OG . SER A 1 331 ? 27.011 17.000 -29.909 1.00 75.69 ? 329 SER A OG 1 ATOM 2169 N N . TYR A 1 332 ? 22.847 15.650 -30.430 1.00 57.40 ? 330 TYR A N 1 ATOM 2170 C CA . TYR A 1 332 ? 21.625 14.854 -30.507 1.00 56.33 ? 330 TYR A CA 1 ATOM 2171 C C . TYR A 1 332 ? 20.832 15.234 -31.767 1.00 61.68 ? 330 TYR A C 1 ATOM 2172 O O . TYR A 1 332 ? 20.466 14.348 -32.554 1.00 60.79 ? 330 TYR A O 1 ATOM 2173 C CB . TYR A 1 332 ? 20.767 15.042 -29.232 1.00 56.64 ? 330 TYR A CB 1 ATOM 2174 C CG . TYR A 1 332 ? 19.328 14.596 -29.386 1.00 58.93 ? 330 TYR A CG 1 ATOM 2175 C CD1 . TYR A 1 332 ? 18.954 13.281 -29.135 1.00 60.51 ? 330 TYR A CD1 1 ATOM 2176 C CD2 . TYR A 1 332 ? 18.335 15.490 -29.792 1.00 60.10 ? 330 TYR A CD2 1 ATOM 2177 C CE1 . TYR A 1 332 ? 17.628 12.862 -29.278 1.00 61.10 ? 330 TYR A CE1 1 ATOM 2178 C CE2 . TYR A 1 332 ? 17.016 15.073 -29.983 1.00 61.04 ? 330 TYR A CE2 1 ATOM 2179 C CZ . TYR A 1 332 ? 16.661 13.760 -29.705 1.00 66.39 ? 330 TYR A CZ 1 ATOM 2180 O OH . TYR A 1 332 ? 15.356 13.338 -29.855 1.00 62.56 ? 330 TYR A OH 1 ATOM 2181 N N . PHE A 1 333 ? 20.578 16.564 -31.945 1.00 58.13 ? 331 PHE A N 1 ATOM 2182 C CA . PHE A 1 333 ? 19.802 17.123 -33.043 1.00 57.13 ? 331 PHE A CA 1 ATOM 2183 C C . PHE A 1 333 ? 20.411 16.824 -34.404 1.00 61.97 ? 331 PHE A C 1 ATOM 2184 O O . PHE A 1 333 ? 19.713 16.285 -35.261 1.00 60.97 ? 331 PHE A O 1 ATOM 2185 C CB . PHE A 1 333 ? 19.535 18.640 -32.857 1.00 58.10 ? 331 PHE A CB 1 ATOM 2186 C CG . PHE A 1 333 ? 18.351 19.123 -33.674 1.00 58.44 ? 331 PHE A CG 1 ATOM 2187 C CD1 . PHE A 1 333 ? 17.052 19.007 -33.184 1.00 59.72 ? 331 PHE A CD1 1 ATOM 2188 C CD2 . PHE A 1 333 ? 18.527 19.603 -34.971 1.00 58.96 ? 331 PHE A CD2 1 ATOM 2189 C CE1 . PHE A 1 333 ? 15.958 19.387 -33.963 1.00 59.67 ? 331 PHE A CE1 1 ATOM 2190 C CE2 . PHE A 1 333 ? 17.427 19.980 -35.752 1.00 60.69 ? 331 PHE A CE2 1 ATOM 2191 C CZ . PHE A 1 333 ? 16.153 19.872 -35.242 1.00 58.61 ? 331 PHE A CZ 1 ATOM 2192 N N . GLN A 1 334 ? 21.708 17.162 -34.596 1.00 59.72 ? 332 GLN A N 1 ATOM 2193 C CA . GLN A 1 334 ? 22.440 16.979 -35.859 1.00 59.75 ? 332 GLN A CA 1 ATOM 2194 C C . GLN A 1 334 ? 22.561 15.501 -36.294 1.00 63.66 ? 332 GLN A C 1 ATOM 2195 O O . GLN A 1 334 ? 22.648 15.226 -37.489 1.00 64.22 ? 332 GLN A O 1 ATOM 2196 C CB . GLN A 1 334 ? 23.811 17.682 -35.812 1.00 61.22 ? 332 GLN A CB 1 ATOM 2197 C CG . GLN A 1 334 ? 23.699 19.217 -35.765 1.00 74.74 ? 332 GLN A CG 1 ATOM 2198 C CD . GLN A 1 334 ? 24.983 19.936 -36.115 1.00 92.83 ? 332 GLN A CD 1 ATOM 2199 O OE1 . GLN A 1 334 ? 25.895 20.098 -35.281 1.00 80.94 ? 332 GLN A OE1 1 ATOM 2200 N NE2 . GLN A 1 334 ? 25.038 20.465 -37.337 1.00 87.29 ? 332 GLN A NE2 1 ATOM 2201 N N . SER A 1 335 ? 22.489 14.558 -35.346 1.00 59.36 ? 333 SER A N 1 ATOM 2202 C CA . SER A 1 335 ? 22.537 13.129 -35.647 1.00 58.55 ? 333 SER A CA 1 ATOM 2203 C C . SER A 1 335 ? 21.148 12.547 -35.995 1.00 60.43 ? 333 SER A C 1 ATOM 2204 O O . SER A 1 335 ? 20.982 11.312 -36.002 1.00 59.50 ? 333 SER A O 1 ATOM 2205 C CB . SER A 1 335 ? 23.191 12.364 -34.499 1.00 63.49 ? 333 SER A CB 1 ATOM 2206 O OG . SER A 1 335 ? 22.617 12.666 -33.237 1.00 77.52 ? 333 SER A OG 1 ATOM 2207 N N . LEU A 1 336 ? 20.151 13.435 -36.280 1.00 55.85 ? 334 LEU A N 1 ATOM 2208 C CA . LEU A 1 336 ? 18.775 13.037 -36.634 1.00 55.58 ? 334 LEU A CA 1 ATOM 2209 C C . LEU A 1 336 ? 18.567 12.921 -38.141 1.00 60.70 ? 334 LEU A C 1 ATOM 2210 O O . LEU A 1 336 ? 18.960 13.820 -38.895 1.00 61.26 ? 334 LEU A O 1 ATOM 2211 C CB . LEU A 1 336 ? 17.687 13.954 -36.018 1.00 55.07 ? 334 LEU A CB 1 ATOM 2212 C CG . LEU A 1 336 ? 17.473 13.878 -34.491 1.00 59.02 ? 334 LEU A CG 1 ATOM 2213 C CD1 . LEU A 1 336 ? 16.704 15.103 -33.967 1.00 58.15 ? 334 LEU A CD1 1 ATOM 2214 C CD2 . LEU A 1 336 ? 16.791 12.581 -34.079 1.00 61.41 ? 334 LEU A CD2 1 ATOM 2215 N N . ASP A 1 337 ? 17.924 11.824 -38.576 1.00 56.43 ? 335 ASP A N 1 ATOM 2216 C CA . ASP A 1 337 ? 17.644 11.590 -39.991 1.00 56.28 ? 335 ASP A CA 1 ATOM 2217 C C . ASP A 1 337 ? 16.202 11.043 -40.202 1.00 61.81 ? 335 ASP A C 1 ATOM 2218 O O . ASP A 1 337 ? 15.592 10.522 -39.257 1.00 60.58 ? 335 ASP A O 1 ATOM 2219 C CB . ASP A 1 337 ? 18.703 10.645 -40.586 1.00 57.96 ? 335 ASP A CB 1 ATOM 2220 C CG . ASP A 1 337 ? 18.508 9.211 -40.156 1.00 66.60 ? 335 ASP A CG 1 ATOM 2221 O OD1 . ASP A 1 337 ? 18.934 8.870 -39.027 1.00 68.72 ? 335 ASP A OD1 1 ATOM 2222 O OD2 . ASP A 1 337 ? 17.829 8.456 -40.898 1.00 67.59 ? 335 ASP A OD2 1 ATOM 2223 N N . PRO A 1 338 ? 15.678 11.098 -41.449 1.00 60.15 ? 336 PRO A N 1 ATOM 2224 C CA . PRO A 1 338 ? 14.301 10.632 -41.700 1.00 60.82 ? 336 PRO A CA 1 ATOM 2225 C C . PRO A 1 338 ? 13.963 9.174 -41.413 1.00 69.19 ? 336 PRO A C 1 ATOM 2226 O O . PRO A 1 338 ? 12.776 8.830 -41.420 1.00 69.22 ? 336 PRO A O 1 ATOM 2227 C CB . PRO A 1 338 ? 14.107 10.912 -43.189 1.00 62.47 ? 336 PRO A CB 1 ATOM 2228 C CG . PRO A 1 338 ? 15.084 11.959 -43.528 1.00 66.52 ? 336 PRO A CG 1 ATOM 2229 C CD . PRO A 1 338 ? 16.260 11.720 -42.657 1.00 61.95 ? 336 PRO A CD 1 ATOM 2230 N N . TRP A 1 339 ? 14.968 8.309 -41.211 1.00 68.80 ? 337 TRP A N 1 ATOM 2231 C CA . TRP A 1 339 ? 14.711 6.881 -41.010 1.00 69.77 ? 337 TRP A CA 1 ATOM 2232 C C . TRP A 1 339 ? 14.817 6.441 -39.583 1.00 73.59 ? 337 TRP A C 1 ATOM 2233 O O . TRP A 1 339 ? 14.105 5.522 -39.176 1.00 73.42 ? 337 TRP A O 1 ATOM 2234 C CB . TRP A 1 339 ? 15.602 6.025 -41.918 1.00 69.11 ? 337 TRP A CB 1 ATOM 2235 C CG . TRP A 1 339 ? 15.240 6.218 -43.349 1.00 70.50 ? 337 TRP A CG 1 ATOM 2236 C CD1 . TRP A 1 339 ? 14.271 5.552 -44.044 1.00 73.64 ? 337 TRP A CD1 1 ATOM 2237 C CD2 . TRP A 1 339 ? 15.690 7.279 -44.199 1.00 70.51 ? 337 TRP A CD2 1 ATOM 2238 N NE1 . TRP A 1 339 ? 14.145 6.086 -45.309 1.00 73.49 ? 337 TRP A NE1 1 ATOM 2239 C CE2 . TRP A 1 339 ? 15.003 7.151 -45.430 1.00 74.68 ? 337 TRP A CE2 1 ATOM 2240 C CE3 . TRP A 1 339 ? 16.652 8.298 -44.061 1.00 71.70 ? 337 TRP A CE3 1 ATOM 2241 C CZ2 . TRP A 1 339 ? 15.246 8.000 -46.512 1.00 73.75 ? 337 TRP A CZ2 1 ATOM 2242 C CZ3 . TRP A 1 339 ? 16.908 9.123 -45.144 1.00 73.21 ? 337 TRP A CZ3 1 ATOM 2243 C CH2 . TRP A 1 339 ? 16.201 8.979 -46.348 1.00 73.85 ? 337 TRP A CH2 1 ATOM 2244 N N . ASN A 1 340 ? 15.701 7.086 -38.824 1.00 69.95 ? 338 ASN A N 1 ATOM 2245 C CA . ASN A 1 340 ? 15.893 6.759 -37.426 1.00 69.50 ? 338 ASN A CA 1 ATOM 2246 C C . ASN A 1 340 ? 14.946 7.561 -36.526 1.00 73.23 ? 338 ASN A C 1 ATOM 2247 O O . ASN A 1 340 ? 14.651 7.121 -35.409 1.00 73.69 ? 338 ASN A O 1 ATOM 2248 C CB . ASN A 1 340 ? 17.365 6.901 -37.039 1.00 69.38 ? 338 ASN A CB 1 ATOM 2249 C CG . ASN A 1 340 ? 18.292 5.923 -37.755 1.00 107.48 ? 338 ASN A CG 1 ATOM 2250 O OD1 . ASN A 1 340 ? 17.876 4.888 -38.301 1.00 104.31 ? 338 ASN A OD1 1 ATOM 2251 N ND2 . ASN A 1 340 ? 19.588 6.213 -37.750 1.00 103.48 ? 338 ASN A ND2 1 ATOM 2252 N N . ASN A 1 341 ? 14.401 8.688 -37.045 1.00 67.37 ? 339 ASN A N 1 ATOM 2253 C CA . ASN A 1 341 ? 13.499 9.551 -36.281 1.00 65.30 ? 339 ASN A CA 1 ATOM 2254 C C . ASN A 1 341 ? 12.012 9.390 -36.666 1.00 66.69 ? 339 ASN A C 1 ATOM 2255 O O . ASN A 1 341 ? 11.302 10.381 -36.875 1.00 66.73 ? 339 ASN A O 1 ATOM 2256 C CB . ASN A 1 341 ? 13.954 11.011 -36.352 1.00 59.57 ? 339 ASN A CB 1 ATOM 2257 C CG . ASN A 1 341 ? 13.420 11.863 -35.236 1.00 69.05 ? 339 ASN A CG 1 ATOM 2258 O OD1 . ASN A 1 341 ? 12.811 11.366 -34.283 1.00 63.44 ? 339 ASN A OD1 1 ATOM 2259 N ND2 . ASN A 1 341 ? 13.598 13.174 -35.351 1.00 58.40 ? 339 ASN A ND2 1 ATOM 2260 N N . SER A 1 342 ? 11.528 8.140 -36.695 1.00 59.93 ? 340 SER A N 1 ATOM 2261 C CA . SER A 1 342 ? 10.122 7.855 -37.007 1.00 58.16 ? 340 SER A CA 1 ATOM 2262 C C . SER A 1 342 ? 9.147 8.347 -35.896 1.00 57.88 ? 340 SER A C 1 ATOM 2263 O O . SER A 1 342 ? 7.970 8.627 -36.192 1.00 56.77 ? 340 SER A O 1 ATOM 2264 C CB . SER A 1 342 ? 9.922 6.369 -37.288 1.00 60.84 ? 340 SER A CB 1 ATOM 2265 O OG . SER A 1 342 ? 10.284 5.607 -36.147 1.00 70.01 ? 340 SER A OG 1 ATOM 2266 N N . ARG A 1 343 ? 9.652 8.470 -34.636 1.00 50.85 ? 341 ARG A N 1 ATOM 2267 C CA . ARG A 1 343 ? 8.865 8.917 -33.486 1.00 49.15 ? 341 ARG A CA 1 ATOM 2268 C C . ARG A 1 343 ? 8.319 10.359 -33.660 1.00 54.08 ? 341 ARG A C 1 ATOM 2269 O O . ARG A 1 343 ? 7.185 10.620 -33.240 1.00 55.34 ? 341 ARG A O 1 ATOM 2270 C CB . ARG A 1 343 ? 9.617 8.728 -32.163 1.00 45.78 ? 341 ARG A CB 1 ATOM 2271 C CG . ARG A 1 343 ? 10.871 9.571 -31.948 1.00 48.83 ? 341 ARG A CG 1 ATOM 2272 C CD . ARG A 1 343 ? 11.239 9.537 -30.456 1.00 45.15 ? 341 ARG A CD 1 ATOM 2273 N NE . ARG A 1 343 ? 12.438 10.327 -30.160 1.00 39.23 ? 341 ARG A NE 1 ATOM 2274 C CZ . ARG A 1 343 ? 13.184 10.186 -29.065 1.00 56.39 ? 341 ARG A CZ 1 ATOM 2275 N NH1 . ARG A 1 343 ? 12.862 9.287 -28.145 1.00 50.71 ? 341 ARG A NH1 1 ATOM 2276 N NH2 . ARG A 1 343 ? 14.256 10.944 -28.884 1.00 37.82 ? 341 ARG A NH2 1 ATOM 2277 N N . ASN A 1 344 ? 9.073 11.254 -34.349 1.00 47.26 ? 342 ASN A N 1 ATOM 2278 C CA . ASN A 1 344 ? 8.606 12.598 -34.637 1.00 45.00 ? 342 ASN A CA 1 ATOM 2279 C C . ASN A 1 344 ? 7.761 12.558 -35.916 1.00 48.08 ? 342 ASN A C 1 ATOM 2280 O O . ASN A 1 344 ? 8.332 12.379 -36.992 1.00 47.38 ? 342 ASN A O 1 ATOM 2281 C CB . ASN A 1 344 ? 9.768 13.578 -34.764 1.00 39.98 ? 342 ASN A CB 1 ATOM 2282 C CG . ASN A 1 344 ? 9.342 15.021 -34.955 1.00 50.80 ? 342 ASN A CG 1 ATOM 2283 O OD1 . ASN A 1 344 ? 8.177 15.345 -35.282 1.00 41.20 ? 342 ASN A OD1 1 ATOM 2284 N ND2 . ASN A 1 344 ? 10.291 15.925 -34.773 1.00 29.71 ? 342 ASN A ND2 1 ATOM 2285 N N . PRO A 1 345 ? 6.414 12.784 -35.839 1.00 44.28 ? 343 PRO A N 1 ATOM 2286 C CA . PRO A 1 345 ? 5.578 12.704 -37.064 1.00 43.37 ? 343 PRO A CA 1 ATOM 2287 C C . PRO A 1 345 ? 5.672 13.896 -38.013 1.00 47.15 ? 343 PRO A C 1 ATOM 2288 O O . PRO A 1 345 ? 5.095 13.879 -39.096 1.00 48.96 ? 343 PRO A O 1 ATOM 2289 C CB . PRO A 1 345 ? 4.166 12.525 -36.510 1.00 44.82 ? 343 PRO A CB 1 ATOM 2290 C CG . PRO A 1 345 ? 4.201 13.221 -35.182 1.00 49.31 ? 343 PRO A CG 1 ATOM 2291 C CD . PRO A 1 345 ? 5.582 13.012 -34.636 1.00 44.79 ? 343 PRO A CD 1 ATOM 2292 N N . TRP A 1 346 ? 6.402 14.916 -37.627 1.00 41.73 ? 344 TRP A N 1 ATOM 2293 C CA . TRP A 1 346 ? 6.551 16.114 -38.443 1.00 40.98 ? 344 TRP A CA 1 ATOM 2294 C C . TRP A 1 346 ? 8.000 16.253 -38.964 1.00 45.76 ? 344 TRP A C 1 ATOM 2295 O O . TRP A 1 346 ? 8.321 17.220 -39.656 1.00 43.73 ? 344 TRP A O 1 ATOM 2296 C CB . TRP A 1 346 ? 6.112 17.345 -37.605 1.00 38.94 ? 344 TRP A CB 1 ATOM 2297 C CG . TRP A 1 346 ? 4.723 17.220 -37.023 1.00 39.35 ? 344 TRP A CG 1 ATOM 2298 C CD1 . TRP A 1 346 ? 3.541 17.265 -37.707 1.00 42.07 ? 344 TRP A CD1 1 ATOM 2299 C CD2 . TRP A 1 346 ? 4.379 17.002 -35.641 1.00 38.79 ? 344 TRP A CD2 1 ATOM 2300 N NE1 . TRP A 1 346 ? 2.480 17.105 -36.838 1.00 41.23 ? 344 TRP A NE1 1 ATOM 2301 C CE2 . TRP A 1 346 ? 2.966 16.927 -35.565 1.00 42.58 ? 344 TRP A CE2 1 ATOM 2302 C CE3 . TRP A 1 346 ? 5.123 16.915 -34.452 1.00 39.84 ? 344 TRP A CE3 1 ATOM 2303 C CZ2 . TRP A 1 346 ? 2.281 16.771 -34.341 1.00 41.55 ? 344 TRP A CZ2 1 ATOM 2304 C CZ3 . TRP A 1 346 ? 4.447 16.728 -33.246 1.00 41.33 ? 344 TRP A CZ3 1 ATOM 2305 C CH2 . TRP A 1 346 ? 3.042 16.658 -33.201 1.00 42.00 ? 344 TRP A CH2 1 ATOM 2306 N N . PHE A 1 347 ? 8.870 15.278 -38.636 1.00 45.56 ? 345 PHE A N 1 ATOM 2307 C CA . PHE A 1 347 ? 10.273 15.336 -39.031 1.00 46.73 ? 345 PHE A CA 1 ATOM 2308 C C . PHE A 1 347 ? 10.507 15.211 -40.571 1.00 53.82 ? 345 PHE A C 1 ATOM 2309 O O . PHE A 1 347 ? 11.383 15.917 -41.118 1.00 51.87 ? 345 PHE A O 1 ATOM 2310 C CB . PHE A 1 347 ? 11.114 14.331 -38.243 1.00 47.93 ? 345 PHE A CB 1 ATOM 2311 C CG . PHE A 1 347 ? 12.595 14.632 -38.345 1.00 49.32 ? 345 PHE A CG 1 ATOM 2312 C CD1 . PHE A 1 347 ? 13.179 15.619 -37.554 1.00 51.98 ? 345 PHE A CD1 1 ATOM 2313 C CD2 . PHE A 1 347 ? 13.403 13.946 -39.251 1.00 49.97 ? 345 PHE A CD2 1 ATOM 2314 C CE1 . PHE A 1 347 ? 14.547 15.901 -37.658 1.00 52.29 ? 345 PHE A CE1 1 ATOM 2315 C CE2 . PHE A 1 347 ? 14.764 14.231 -39.351 1.00 51.83 ? 345 PHE A CE2 1 ATOM 2316 C CZ . PHE A 1 347 ? 15.325 15.215 -38.565 1.00 50.01 ? 345 PHE A CZ 1 ATOM 2317 N N . ARG A 1 348 ? 9.713 14.336 -41.260 1.00 52.13 ? 346 ARG A N 1 ATOM 2318 C CA . ARG A 1 348 ? 9.814 14.147 -42.717 1.00 51.70 ? 346 ARG A CA 1 ATOM 2319 C C . ARG A 1 348 ? 9.471 15.461 -43.415 1.00 56.54 ? 346 ARG A C 1 ATOM 2320 O O . ARG A 1 348 ? 10.244 15.941 -44.238 1.00 56.74 ? 346 ARG A O 1 ATOM 2321 C CB . ARG A 1 348 ? 8.924 12.986 -43.204 1.00 49.63 ? 346 ARG A CB 1 ATOM 2322 C CG . ARG A 1 348 ? 9.634 11.632 -43.159 1.00 60.58 ? 346 ARG A CG 1 ATOM 2323 C CD . ARG A 1 348 ? 8.953 10.557 -44.000 1.00 73.48 ? 346 ARG A CD 1 ATOM 2324 N NE . ARG A 1 348 ? 9.500 9.228 -43.716 1.00 85.38 ? 346 ARG A NE 1 ATOM 2325 C CZ . ARG A 1 348 ? 10.385 8.591 -44.480 1.00 98.92 ? 346 ARG A CZ 1 ATOM 2326 N NH1 . ARG A 1 348 ? 10.810 9.137 -45.612 1.00 89.18 ? 346 ARG A NH1 1 ATOM 2327 N NH2 . ARG A 1 348 ? 10.839 7.395 -44.126 1.00 77.85 ? 346 ARG A NH2 1 ATOM 2328 N N . GLU A 1 349 ? 8.373 16.089 -42.994 1.00 53.46 ? 347 GLU A N 1 ATOM 2329 C CA . GLU A 1 349 ? 7.904 17.381 -43.492 1.00 53.95 ? 347 GLU A CA 1 ATOM 2330 C C . GLU A 1 349 ? 8.961 18.498 -43.347 1.00 57.58 ? 347 GLU A C 1 ATOM 2331 O O . GLU A 1 349 ? 9.133 19.330 -44.239 1.00 56.47 ? 347 GLU A O 1 ATOM 2332 C CB . GLU A 1 349 ? 6.674 17.764 -42.691 1.00 55.47 ? 347 GLU A CB 1 ATOM 2333 C CG . GLU A 1 349 ? 5.783 18.745 -43.410 1.00 67.52 ? 347 GLU A CG 1 ATOM 2334 C CD . GLU A 1 349 ? 4.594 19.137 -42.568 1.00 78.32 ? 347 GLU A CD 1 ATOM 2335 O OE1 . GLU A 1 349 ? 4.087 20.262 -42.773 1.00 63.55 ? 347 GLU A OE1 1 ATOM 2336 O OE2 . GLU A 1 349 ? 4.194 18.342 -41.682 1.00 64.42 ? 347 GLU A OE2 1 ATOM 2337 N N . PHE A 1 350 ? 9.635 18.517 -42.204 1.00 54.39 ? 348 PHE A N 1 ATOM 2338 C CA . PHE A 1 350 ? 10.674 19.477 -41.909 1.00 54.10 ? 348 PHE A CA 1 ATOM 2339 C C . PHE A 1 350 ? 11.859 19.222 -42.834 1.00 61.25 ? 348 PHE A C 1 ATOM 2340 O O . PHE A 1 350 ? 12.377 20.181 -43.402 1.00 61.25 ? 348 PHE A O 1 ATOM 2341 C CB . PHE A 1 350 ? 11.055 19.401 -40.417 1.00 55.04 ? 348 PHE A CB 1 ATOM 2342 C CG . PHE A 1 350 ? 12.466 19.818 -40.085 1.00 55.53 ? 348 PHE A CG 1 ATOM 2343 C CD1 . PHE A 1 350 ? 12.817 21.162 -40.028 1.00 58.22 ? 348 PHE A CD1 1 ATOM 2344 C CD2 . PHE A 1 350 ? 13.442 18.866 -39.806 1.00 56.15 ? 348 PHE A CD2 1 ATOM 2345 C CE1 . PHE A 1 350 ? 14.131 21.543 -39.726 1.00 59.01 ? 348 PHE A CE1 1 ATOM 2346 C CE2 . PHE A 1 350 ? 14.747 19.251 -39.491 1.00 58.32 ? 348 PHE A CE2 1 ATOM 2347 C CZ . PHE A 1 350 ? 15.087 20.584 -39.467 1.00 56.55 ? 348 PHE A CZ 1 ATOM 2348 N N . TRP A 1 351 ? 12.266 17.929 -43.011 1.00 59.85 ? 349 TRP A N 1 ATOM 2349 C CA . TRP A 1 351 ? 13.386 17.522 -43.881 1.00 59.55 ? 349 TRP A CA 1 ATOM 2350 C C . TRP A 1 351 ? 13.185 18.064 -45.299 1.00 60.63 ? 349 TRP A C 1 ATOM 2351 O O . TRP A 1 351 ? 14.041 18.806 -45.805 1.00 59.41 ? 349 TRP A O 1 ATOM 2352 C CB . TRP A 1 351 ? 13.559 15.993 -43.891 1.00 58.85 ? 349 TRP A CB 1 ATOM 2353 C CG . TRP A 1 351 ? 14.920 15.560 -44.347 1.00 60.57 ? 349 TRP A CG 1 ATOM 2354 C CD1 . TRP A 1 351 ? 15.330 15.374 -45.636 1.00 63.68 ? 349 TRP A CD1 1 ATOM 2355 C CD2 . TRP A 1 351 ? 16.077 15.350 -43.524 1.00 60.61 ? 349 TRP A CD2 1 ATOM 2356 N NE1 . TRP A 1 351 ? 16.673 15.063 -45.669 1.00 63.20 ? 349 TRP A NE1 1 ATOM 2357 C CE2 . TRP A 1 351 ? 17.151 15.015 -44.385 1.00 64.30 ? 349 TRP A CE2 1 ATOM 2358 C CE3 . TRP A 1 351 ? 16.302 15.362 -42.137 1.00 61.93 ? 349 TRP A CE3 1 ATOM 2359 C CZ2 . TRP A 1 351 ? 18.425 14.695 -43.906 1.00 63.15 ? 349 TRP A CZ2 1 ATOM 2360 C CZ3 . TRP A 1 351 ? 17.568 15.045 -41.664 1.00 63.43 ? 349 TRP A CZ3 1 ATOM 2361 C CH2 . TRP A 1 351 ? 18.613 14.721 -42.544 1.00 63.97 ? 349 TRP A CH2 1 ATOM 2362 N N . GLU A 1 352 ? 11.998 17.761 -45.884 1.00 55.95 ? 350 GLU A N 1 ATOM 2363 C CA . GLU A 1 352 ? 11.527 18.198 -47.207 1.00 55.11 ? 350 GLU A CA 1 ATOM 2364 C C . GLU A 1 352 ? 11.571 19.731 -47.337 1.00 58.49 ? 350 GLU A C 1 ATOM 2365 O O . GLU A 1 352 ? 11.978 20.241 -48.376 1.00 58.40 ? 350 GLU A O 1 ATOM 2366 C CB . GLU A 1 352 ? 10.094 17.681 -47.470 1.00 56.22 ? 350 GLU A CB 1 ATOM 2367 C CG . GLU A 1 352 ? 10.010 16.199 -47.812 1.00 63.83 ? 350 GLU A CG 1 ATOM 2368 C CD . GLU A 1 352 ? 8.713 15.685 -48.418 1.00 82.79 ? 350 GLU A CD 1 ATOM 2369 O OE1 . GLU A 1 352 ? 8.771 14.673 -49.155 1.00 82.13 ? 350 GLU A OE1 1 ATOM 2370 O OE2 . GLU A 1 352 ? 7.641 16.279 -48.158 1.00 73.11 ? 350 GLU A OE2 1 ATOM 2371 N N . GLN A 1 353 ? 11.187 20.457 -46.274 1.00 54.41 ? 351 GLN A N 1 ATOM 2372 C CA . GLN A 1 353 ? 11.205 21.920 -46.240 1.00 53.76 ? 351 GLN A CA 1 ATOM 2373 C C . GLN A 1 353 ? 12.635 22.489 -46.134 1.00 56.59 ? 351 GLN A C 1 ATOM 2374 O O . GLN A 1 353 ? 12.984 23.395 -46.899 1.00 54.56 ? 351 GLN A O 1 ATOM 2375 C CB . GLN A 1 353 ? 10.327 22.432 -45.090 1.00 54.87 ? 351 GLN A CB 1 ATOM 2376 C CG . GLN A 1 353 ? 10.156 23.936 -45.063 1.00 64.31 ? 351 GLN A CG 1 ATOM 2377 C CD . GLN A 1 353 ? 9.598 24.380 -43.745 1.00 83.92 ? 351 GLN A CD 1 ATOM 2378 O OE1 . GLN A 1 353 ? 8.386 24.356 -43.535 1.00 83.51 ? 351 GLN A OE1 1 ATOM 2379 N NE2 . GLN A 1 353 ? 10.467 24.807 -42.830 1.00 67.10 ? 351 GLN A NE2 1 ATOM 2380 N N . ARG A 1 354 ? 13.445 21.966 -45.182 1.00 53.94 ? 352 ARG A N 1 ATOM 2381 C CA . ARG A 1 354 ? 14.807 22.438 -44.904 1.00 53.87 ? 352 ARG A CA 1 ATOM 2382 C C . ARG A 1 354 ? 15.768 22.214 -46.060 1.00 57.63 ? 352 ARG A C 1 ATOM 2383 O O . ARG A 1 354 ? 16.576 23.096 -46.365 1.00 55.41 ? 352 ARG A O 1 ATOM 2384 C CB . ARG A 1 354 ? 15.354 21.830 -43.584 1.00 53.74 ? 352 ARG A CB 1 ATOM 2385 C CG . ARG A 1 354 ? 16.865 22.067 -43.291 1.00 60.65 ? 352 ARG A CG 1 ATOM 2386 C CD . ARG A 1 354 ? 17.198 23.540 -43.092 1.00 74.52 ? 352 ARG A CD 1 ATOM 2387 N NE . ARG A 1 354 ? 18.638 23.810 -43.059 1.00 88.06 ? 352 ARG A NE 1 ATOM 2388 C CZ . ARG A 1 354 ? 19.385 24.116 -44.120 1.00 99.63 ? 352 ARG A CZ 1 ATOM 2389 N NH1 . ARG A 1 354 ? 20.677 24.364 -43.979 1.00 82.53 ? 352 ARG A NH1 1 ATOM 2390 N NH2 . ARG A 1 354 ? 18.845 24.169 -45.330 1.00 88.04 ? 352 ARG A NH2 1 ATOM 2391 N N . PHE A 1 355 ? 15.682 21.034 -46.692 1.00 56.02 ? 353 PHE A N 1 ATOM 2392 C CA . PHE A 1 355 ? 16.604 20.656 -47.754 1.00 56.52 ? 353 PHE A CA 1 ATOM 2393 C C . PHE A 1 355 ? 16.012 20.729 -49.167 1.00 63.96 ? 353 PHE A C 1 ATOM 2394 O O . PHE A 1 355 ? 16.646 20.260 -50.122 1.00 63.75 ? 353 PHE A O 1 ATOM 2395 C CB . PHE A 1 355 ? 17.194 19.274 -47.457 1.00 57.63 ? 353 PHE A CB 1 ATOM 2396 C CG . PHE A 1 355 ? 18.028 19.231 -46.209 1.00 58.53 ? 353 PHE A CG 1 ATOM 2397 C CD1 . PHE A 1 355 ? 19.222 19.944 -46.124 1.00 61.10 ? 353 PHE A CD1 1 ATOM 2398 C CD2 . PHE A 1 355 ? 17.636 18.461 -45.118 1.00 61.12 ? 353 PHE A CD2 1 ATOM 2399 C CE1 . PHE A 1 355 ? 20.008 19.895 -44.960 1.00 61.95 ? 353 PHE A CE1 1 ATOM 2400 C CE2 . PHE A 1 355 ? 18.427 18.400 -43.959 1.00 63.73 ? 353 PHE A CE2 1 ATOM 2401 C CZ . PHE A 1 355 ? 19.609 19.116 -43.890 1.00 61.62 ? 353 PHE A CZ 1 ATOM 2402 N N . ARG A 1 356 ? 14.836 21.374 -49.304 1.00 62.63 ? 354 ARG A N 1 ATOM 2403 C CA . ARG A 1 356 ? 14.126 21.596 -50.570 1.00 63.12 ? 354 ARG A CA 1 ATOM 2404 C C . ARG A 1 356 ? 14.139 20.338 -51.455 1.00 68.17 ? 354 ARG A C 1 ATOM 2405 O O . ARG A 1 356 ? 14.583 20.382 -52.600 1.00 67.98 ? 354 ARG A O 1 ATOM 2406 C CB . ARG A 1 356 ? 14.704 22.818 -51.307 1.00 63.53 ? 354 ARG A CB 1 ATOM 2407 C CG . ARG A 1 356 ? 14.417 24.166 -50.662 1.00 76.45 ? 354 ARG A CG 1 ATOM 2408 C CD . ARG A 1 356 ? 14.794 25.320 -51.581 1.00 94.46 ? 354 ARG A CD 1 ATOM 2409 N NE . ARG A 1 356 ? 16.227 25.341 -51.904 1.00 111.99 ? 354 ARG A NE 1 ATOM 2410 C CZ . ARG A 1 356 ? 16.752 25.929 -52.978 1.00 131.54 ? 354 ARG A CZ 1 ATOM 2411 N NH1 . ARG A 1 356 ? 15.969 26.539 -53.862 1.00 122.77 ? 354 ARG A NH1 1 ATOM 2412 N NH2 . ARG A 1 356 ? 18.063 25.892 -53.188 1.00 115.89 ? 354 ARG A NH2 1 ATOM 2413 N N . CYS A 1 357 ? 13.688 19.210 -50.890 1.00 65.85 ? 355 CYS A N 1 ATOM 2414 C CA . CYS A 1 357 ? 13.645 17.906 -51.547 1.00 66.06 ? 355 CYS A CA 1 ATOM 2415 C C . CYS A 1 357 ? 12.301 17.165 -51.366 1.00 69.58 ? 355 CYS A C 1 ATOM 2416 O O . CYS A 1 357 ? 11.352 17.707 -50.793 1.00 68.33 ? 355 CYS A O 1 ATOM 2417 C CB . CYS A 1 357 ? 14.830 17.052 -51.102 1.00 66.83 ? 355 CYS A CB 1 ATOM 2418 S SG . CYS A 1 357 ? 14.902 16.747 -49.322 1.00 71.13 ? 355 CYS A SG 1 ATOM 2419 N N . SER A 1 358 ? 12.230 15.921 -51.868 1.00 67.26 ? 356 SER A N 1 ATOM 2420 C CA . SER A 1 358 ? 11.035 15.093 -51.790 1.00 67.53 ? 356 SER A CA 1 ATOM 2421 C C . SER A 1 358 ? 11.375 13.618 -51.675 1.00 72.20 ? 356 SER A C 1 ATOM 2422 O O . SER A 1 358 ? 12.166 13.093 -52.463 1.00 71.81 ? 356 SER A O 1 ATOM 2423 C CB . SER A 1 358 ? 10.150 15.319 -53.012 1.00 71.63 ? 356 SER A CB 1 ATOM 2424 O OG . SER A 1 358 ? 9.020 14.464 -52.996 1.00 83.61 ? 356 SER A OG 1 ATOM 2425 N N . PHE A 1 359 ? 10.733 12.943 -50.713 1.00 69.46 ? 357 PHE A N 1 ATOM 2426 C CA . PHE A 1 359 ? 10.866 11.504 -50.507 1.00 69.71 ? 357 PHE A CA 1 ATOM 2427 C C . PHE A 1 359 ? 10.238 10.760 -51.693 1.00 76.87 ? 357 PHE A C 1 ATOM 2428 O O . PHE A 1 359 ? 10.776 9.723 -52.092 1.00 76.56 ? 357 PHE A O 1 ATOM 2429 C CB . PHE A 1 359 ? 10.233 11.073 -49.162 1.00 70.81 ? 357 PHE A CB 1 ATOM 2430 C CG . PHE A 1 359 ? 10.955 11.629 -47.956 1.00 71.24 ? 357 PHE A CG 1 ATOM 2431 C CD1 . PHE A 1 359 ? 12.242 11.213 -47.641 1.00 73.61 ? 357 PHE A CD1 1 ATOM 2432 C CD2 . PHE A 1 359 ? 10.366 12.598 -47.163 1.00 72.10 ? 357 PHE A CD2 1 ATOM 2433 C CE1 . PHE A 1 359 ? 12.909 11.735 -46.538 1.00 74.00 ? 357 PHE A CE1 1 ATOM 2434 C CE2 . PHE A 1 359 ? 11.051 13.145 -46.084 1.00 74.39 ? 357 PHE A CE2 1 ATOM 2435 C CZ . PHE A 1 359 ? 12.309 12.701 -45.770 1.00 72.43 ? 357 PHE A CZ 1 ATOM 2436 N N . ARG A 1 360 ? 9.149 11.342 -52.300 1.00 75.58 ? 358 ARG A N 1 ATOM 2437 C CA . ARG A 1 360 ? 8.427 10.831 -53.481 1.00 76.58 ? 358 ARG A CA 1 ATOM 2438 C C . ARG A 1 360 ? 9.357 10.622 -54.680 1.00 82.61 ? 358 ARG A C 1 ATOM 2439 O O . ARG A 1 360 ? 9.045 9.816 -55.562 1.00 82.79 ? 358 ARG A O 1 ATOM 2440 C CB . ARG A 1 360 ? 7.269 11.764 -53.889 1.00 77.45 ? 358 ARG A CB 1 ATOM 2441 C CG . ARG A 1 360 ? 6.049 11.004 -54.420 1.00 94.07 ? 358 ARG A CG 1 ATOM 2442 C CD . ARG A 1 360 ? 5.091 11.870 -55.234 1.00 110.10 ? 358 ARG A CD 1 ATOM 2443 N NE . ARG A 1 360 ? 4.163 12.644 -54.403 1.00 115.17 ? 358 ARG A NE 1 ATOM 2444 C CZ . ARG A 1 360 ? 3.296 13.540 -54.872 1.00 124.70 ? 358 ARG A CZ 1 ATOM 2445 N NH1 . ARG A 1 360 ? 3.224 13.789 -56.176 1.00 105.45 ? 358 ARG A NH1 1 ATOM 2446 N NH2 . ARG A 1 360 ? 2.496 14.196 -54.041 1.00 110.66 ? 358 ARG A NH2 1 ATOM 2447 N N . GLN A 1 361 ? 10.499 11.340 -54.701 1.00 79.32 ? 359 GLN A N 1 ATOM 2448 C CA . GLN A 1 361 ? 11.500 11.243 -55.753 1.00 79.02 ? 359 GLN A CA 1 ATOM 2449 C C . GLN A 1 361 ? 12.907 10.940 -55.225 1.00 80.70 ? 359 GLN A C 1 ATOM 2450 O O . GLN A 1 361 ? 13.875 11.414 -55.812 1.00 80.19 ? 359 GLN A O 1 ATOM 2451 C CB . GLN A 1 361 ? 11.475 12.502 -56.638 1.00 80.94 ? 359 GLN A CB 1 ATOM 2452 C CG . GLN A 1 361 ? 10.526 12.377 -57.841 1.00 103.51 ? 359 GLN A CG 1 ATOM 2453 C CD . GLN A 1 361 ? 11.099 11.604 -59.023 1.00 122.34 ? 359 GLN A CD 1 ATOM 2454 O OE1 . GLN A 1 361 ? 12.324 11.497 -59.211 1.00 113.70 ? 359 GLN A OE1 1 ATOM 2455 N NE2 . GLN A 1 361 ? 10.214 11.084 -59.879 1.00 115.56 ? 359 GLN A NE2 1 ATOM 2456 N N . ARG A 1 362 ? 13.017 10.137 -54.134 1.00 76.47 ? 360 ARG A N 1 ATOM 2457 C CA . ARG A 1 362 ? 14.259 9.688 -53.458 1.00 76.10 ? 360 ARG A CA 1 ATOM 2458 C C . ARG A 1 362 ? 15.407 10.720 -53.486 1.00 78.35 ? 360 ARG A C 1 ATOM 2459 O O . ARG A 1 362 ? 16.584 10.366 -53.608 1.00 77.11 ? 360 ARG A O 1 ATOM 2460 C CB . ARG A 1 362 ? 14.726 8.328 -54.006 1.00 77.50 ? 360 ARG A CB 1 ATOM 2461 C CG . ARG A 1 362 ? 13.998 7.123 -53.415 1.00 90.50 ? 360 ARG A CG 1 ATOM 2462 C CD . ARG A 1 362 ? 14.189 5.893 -54.291 1.00 100.73 ? 360 ARG A CD 1 ATOM 2463 N NE . ARG A 1 362 ? 13.950 4.638 -53.573 1.00 104.86 ? 360 ARG A NE 1 ATOM 2464 C CZ . ARG A 1 362 ? 14.875 3.704 -53.367 1.00 116.09 ? 360 ARG A CZ 1 ATOM 2465 N NH1 . ARG A 1 362 ? 16.114 3.872 -53.819 1.00 100.36 ? 360 ARG A NH1 1 ATOM 2466 N NH2 . ARG A 1 362 ? 14.569 2.591 -52.713 1.00 102.44 ? 360 ARG A NH2 1 ATOM 2467 N N . ASP A 1 363 ? 15.027 11.998 -53.341 1.00 74.39 ? 361 ASP A N 1 ATOM 2468 C CA . ASP A 1 363 ? 15.850 13.211 -53.370 1.00 73.68 ? 361 ASP A CA 1 ATOM 2469 C C . ASP A 1 363 ? 16.612 13.486 -52.044 1.00 73.83 ? 361 ASP A C 1 ATOM 2470 O O . ASP A 1 363 ? 17.752 13.952 -52.073 1.00 72.41 ? 361 ASP A O 1 ATOM 2471 C CB . ASP A 1 363 ? 14.884 14.412 -53.561 1.00 76.10 ? 361 ASP A CB 1 ATOM 2472 C CG . ASP A 1 363 ? 14.796 15.084 -54.911 1.00 87.72 ? 361 ASP A CG 1 ATOM 2473 O OD1 . ASP A 1 363 ? 13.876 14.733 -55.688 1.00 94.61 ? 361 ASP A OD1 1 ATOM 2474 O OD2 . ASP A 1 363 ? 15.516 16.090 -55.116 1.00 87.75 ? 361 ASP A OD2 1 ATOM 2475 N N . CYS A 1 364 ? 15.931 13.266 -50.896 1.00 69.17 ? 362 CYS A N 1 ATOM 2476 C CA . CYS A 1 364 ? 16.319 13.682 -49.544 1.00 68.58 ? 362 CYS A CA 1 ATOM 2477 C C . CYS A 1 364 ? 17.486 12.917 -48.878 1.00 72.19 ? 362 CYS A C 1 ATOM 2478 O O . CYS A 1 364 ? 18.352 13.588 -48.321 1.00 71.02 ? 362 CYS A O 1 ATOM 2479 C CB . CYS A 1 364 ? 15.095 13.718 -48.635 1.00 68.21 ? 362 CYS A CB 1 ATOM 2480 S SG . CYS A 1 364 ? 13.876 14.995 -49.080 1.00 71.52 ? 362 CYS A SG 1 ATOM 2481 N N . ALA A 1 365 ? 17.526 11.569 -48.919 1.00 69.58 ? 363 ALA A N 1 ATOM 2482 C CA . ALA A 1 365 ? 18.612 10.755 -48.328 1.00 69.59 ? 363 ALA A CA 1 ATOM 2483 C C . ALA A 1 365 ? 20.005 11.417 -48.393 1.00 73.04 ? 363 ALA A C 1 ATOM 2484 O O . ALA A 1 365 ? 20.730 11.450 -47.397 1.00 72.91 ? 363 ALA A O 1 ATOM 2485 C CB . ALA A 1 365 ? 18.652 9.378 -48.981 1.00 70.29 ? 363 ALA A CB 1 ATOM 2486 N N . ALA A 1 366 ? 20.317 12.006 -49.551 1.00 69.63 ? 364 ALA A N 1 ATOM 2487 C CA . ALA A 1 366 ? 21.543 12.714 -49.909 1.00 70.39 ? 364 ALA A CA 1 ATOM 2488 C C . ALA A 1 366 ? 22.029 13.769 -48.895 1.00 74.83 ? 364 ALA A C 1 ATOM 2489 O O . ALA A 1 366 ? 23.154 14.266 -49.037 1.00 75.58 ? 364 ALA A O 1 ATOM 2490 C CB . ALA A 1 366 ? 21.338 13.383 -51.266 1.00 71.51 ? 364 ALA A CB 1 ATOM 2491 N N . HIS A 1 367 ? 21.254 13.998 -47.841 1.00 69.04 ? 365 HIS A N 1 ATOM 2492 C CA . HIS A 1 367 ? 21.548 15.070 -46.903 1.00 67.49 ? 365 HIS A CA 1 ATOM 2493 C C . HIS A 1 367 ? 21.831 14.670 -45.489 1.00 70.11 ? 365 HIS A C 1 ATOM 2494 O O . HIS A 1 367 ? 21.709 13.530 -45.115 1.00 70.62 ? 365 HIS A O 1 ATOM 2495 C CB . HIS A 1 367 ? 20.389 16.043 -46.839 1.00 67.66 ? 365 HIS A CB 1 ATOM 2496 C CG . HIS A 1 367 ? 20.127 16.757 -48.113 1.00 70.32 ? 365 HIS A CG 1 ATOM 2497 N ND1 . HIS A 1 367 ? 19.089 16.423 -48.943 1.00 71.69 ? 365 HIS A ND1 1 ATOM 2498 C CD2 . HIS A 1 367 ? 20.759 17.795 -48.695 1.00 71.61 ? 365 HIS A CD2 1 ATOM 2499 C CE1 . HIS A 1 367 ? 19.091 17.226 -49.984 1.00 70.97 ? 365 HIS A CE1 1 ATOM 2500 N NE2 . HIS A 1 367 ? 20.095 18.067 -49.858 1.00 71.31 ? 365 HIS A NE2 1 ATOM 2501 N N . SER A 1 368 ? 22.171 15.672 -44.703 1.00 65.06 ? 366 SER A N 1 ATOM 2502 C CA . SER A 1 368 ? 22.476 15.524 -43.286 1.00 65.12 ? 366 SER A CA 1 ATOM 2503 C C . SER A 1 368 ? 22.482 16.907 -42.616 1.00 70.00 ? 366 SER A C 1 ATOM 2504 O O . SER A 1 368 ? 22.983 17.890 -43.184 1.00 69.28 ? 366 SER A O 1 ATOM 2505 C CB . SER A 1 368 ? 23.817 14.810 -43.080 1.00 68.49 ? 366 SER A CB 1 ATOM 2506 O OG . SER A 1 368 ? 24.202 14.670 -41.719 1.00 77.59 ? 366 SER A OG 1 ATOM 2507 N N . LEU A 1 369 ? 21.967 16.958 -41.381 1.00 67.73 ? 367 LEU A N 1 ATOM 2508 C CA . LEU A 1 369 ? 21.917 18.173 -40.572 1.00 68.28 ? 367 LEU A CA 1 ATOM 2509 C C . LEU A 1 369 ? 23.289 18.552 -40.003 1.00 75.47 ? 367 LEU A C 1 ATOM 2510 O O . LEU A 1 369 ? 23.439 19.664 -39.487 1.00 76.24 ? 367 LEU A O 1 ATOM 2511 C CB . LEU A 1 369 ? 20.874 18.030 -39.445 1.00 67.98 ? 367 LEU A CB 1 ATOM 2512 C CG . LEU A 1 369 ? 19.400 18.030 -39.872 1.00 71.21 ? 367 LEU A CG 1 ATOM 2513 C CD1 . LEU A 1 369 ? 18.580 17.197 -38.927 1.00 70.76 ? 367 LEU A CD1 1 ATOM 2514 C CD2 . LEU A 1 369 ? 18.853 19.445 -39.940 1.00 71.46 ? 367 LEU A CD2 1 ATOM 2515 N N . ARG A 1 370 ? 24.279 17.630 -40.086 1.00 73.78 ? 368 ARG A N 1 ATOM 2516 C CA . ARG A 1 370 ? 25.640 17.838 -39.579 1.00 74.82 ? 368 ARG A CA 1 ATOM 2517 C C . ARG A 1 370 ? 26.505 18.641 -40.554 1.00 81.69 ? 368 ARG A C 1 ATOM 2518 O O . ARG A 1 370 ? 27.421 19.358 -40.125 1.00 81.07 ? 368 ARG A O 1 ATOM 2519 C CB . ARG A 1 370 ? 26.310 16.506 -39.233 1.00 74.26 ? 368 ARG A CB 1 ATOM 2520 C CG . ARG A 1 370 ? 27.195 16.600 -37.995 1.00 83.41 ? 368 ARG A CG 1 ATOM 2521 C CD . ARG A 1 370 ? 27.352 15.246 -37.338 1.00 90.15 ? 368 ARG A CD 1 ATOM 2522 N NE . ARG A 1 370 ? 26.916 15.272 -35.941 1.00 102.30 ? 368 ARG A NE 1 ATOM 2523 C CZ . ARG A 1 370 ? 26.351 14.244 -35.316 1.00 120.86 ? 368 ARG A CZ 1 ATOM 2524 N NH1 . ARG A 1 370 ? 25.987 14.352 -34.043 1.00 103.03 ? 368 ARG A NH1 1 ATOM 2525 N NH2 . ARG A 1 370 ? 26.144 13.099 -35.957 1.00 114.07 ? 368 ARG A NH2 1 ATOM 2526 N N . ALA A 1 371 ? 26.205 18.518 -41.864 1.00 79.46 ? 369 ALA A N 1 ATOM 2527 C CA . ALA A 1 371 ? 26.904 19.219 -42.940 1.00 79.50 ? 369 ALA A CA 1 ATOM 2528 C C . ALA A 1 371 ? 26.612 20.714 -42.855 1.00 83.14 ? 369 ALA A C 1 ATOM 2529 O O . ALA A 1 371 ? 27.478 21.543 -43.164 1.00 83.49 ? 369 ALA A O 1 ATOM 2530 C CB . ALA A 1 371 ? 26.448 18.676 -44.287 1.00 80.39 ? 369 ALA A CB 1 ATOM 2531 N N . VAL A 1 372 ? 25.385 21.045 -42.412 1.00 77.94 ? 370 VAL A N 1 ATOM 2532 C CA . VAL A 1 372 ? 24.897 22.413 -42.266 1.00 76.17 ? 370 VAL A CA 1 ATOM 2533 C C . VAL A 1 372 ? 25.142 22.944 -40.835 1.00 76.22 ? 370 VAL A C 1 ATOM 2534 O O . VAL A 1 372 ? 25.318 22.142 -39.907 1.00 73.97 ? 370 VAL A O 1 ATOM 2535 C CB . VAL A 1 372 ? 23.423 22.578 -42.752 1.00 79.83 ? 370 VAL A CB 1 ATOM 2536 C CG1 . VAL A 1 372 ? 23.340 22.438 -44.269 1.00 79.60 ? 370 VAL A CG1 1 ATOM 2537 C CG2 . VAL A 1 372 ? 22.460 21.612 -42.055 1.00 79.38 ? 370 VAL A CG2 1 ATOM 2538 N N . PRO A 1 373 ? 25.196 24.286 -40.643 1.00 72.37 ? 371 PRO A N 1 ATOM 2539 C CA . PRO A 1 373 ? 25.463 24.823 -39.295 1.00 72.63 ? 371 PRO A CA 1 ATOM 2540 C C . PRO A 1 373 ? 24.286 24.697 -38.321 1.00 76.67 ? 371 PRO A C 1 ATOM 2541 O O . PRO A 1 373 ? 23.119 24.759 -38.734 1.00 77.39 ? 371 PRO A O 1 ATOM 2542 C CB . PRO A 1 373 ? 25.818 26.297 -39.555 1.00 74.46 ? 371 PRO A CB 1 ATOM 2543 C CG . PRO A 1 373 ? 25.937 26.430 -41.066 1.00 78.41 ? 371 PRO A CG 1 ATOM 2544 C CD . PRO A 1 373 ? 25.052 25.379 -41.623 1.00 73.51 ? 371 PRO A CD 1 ATOM 2545 N N . PHE A 1 374 ? 24.596 24.512 -37.024 1.00 70.41 ? 372 PHE A N 1 ATOM 2546 C CA . PHE A 1 374 ? 23.573 24.400 -36.003 1.00 68.84 ? 372 PHE A CA 1 ATOM 2547 C C . PHE A 1 374 ? 23.517 25.643 -35.133 1.00 73.20 ? 372 PHE A C 1 ATOM 2548 O O . PHE A 1 374 ? 24.513 26.009 -34.492 1.00 72.76 ? 372 PHE A O 1 ATOM 2549 C CB . PHE A 1 374 ? 23.734 23.138 -35.148 1.00 69.83 ? 372 PHE A CB 1 ATOM 2550 C CG . PHE A 1 374 ? 22.600 22.965 -34.165 1.00 70.85 ? 372 PHE A CG 1 ATOM 2551 C CD1 . PHE A 1 374 ? 21.352 22.519 -34.588 1.00 73.28 ? 372 PHE A CD1 1 ATOM 2552 C CD2 . PHE A 1 374 ? 22.763 23.294 -32.825 1.00 72.54 ? 372 PHE A CD2 1 ATOM 2553 C CE1 . PHE A 1 374 ? 20.296 22.392 -33.685 1.00 74.12 ? 372 PHE A CE1 1 ATOM 2554 C CE2 . PHE A 1 374 ? 21.707 23.155 -31.919 1.00 74.89 ? 372 PHE A CE2 1 ATOM 2555 C CZ . PHE A 1 374 ? 20.483 22.704 -32.355 1.00 72.96 ? 372 PHE A CZ 1 ATOM 2556 N N . GLU A 1 375 ? 22.341 26.289 -35.117 1.00 68.62 ? 373 GLU A N 1 ATOM 2557 C CA . GLU A 1 375 ? 22.121 27.453 -34.291 1.00 68.16 ? 373 GLU A CA 1 ATOM 2558 C C . GLU A 1 375 ? 21.046 27.094 -33.271 1.00 69.00 ? 373 GLU A C 1 ATOM 2559 O O . GLU A 1 375 ? 19.871 26.922 -33.640 1.00 68.41 ? 373 GLU A O 1 ATOM 2560 C CB . GLU A 1 375 ? 21.740 28.679 -35.135 1.00 69.96 ? 373 GLU A CB 1 ATOM 2561 C CG . GLU A 1 375 ? 22.911 29.593 -35.462 1.00 83.82 ? 373 GLU A CG 1 ATOM 2562 C CD . GLU A 1 375 ? 23.653 29.279 -36.750 1.00 118.95 ? 373 GLU A CD 1 ATOM 2563 O OE1 . GLU A 1 375 ? 23.003 29.196 -37.820 1.00 103.95 ? 373 GLU A OE1 1 ATOM 2564 O OE2 . GLU A 1 375 ? 24.899 29.160 -36.692 1.00 127.59 ? 373 GLU A OE2 1 ATOM 2565 N N . GLN A 1 376 ? 21.458 26.933 -31.989 1.00 61.96 ? 374 GLN A N 1 ATOM 2566 C CA . GLN A 1 376 ? 20.510 26.575 -30.929 1.00 60.06 ? 374 GLN A CA 1 ATOM 2567 C C . GLN A 1 376 ? 19.485 27.681 -30.663 1.00 60.98 ? 374 GLN A C 1 ATOM 2568 O O . GLN A 1 376 ? 19.854 28.833 -30.385 1.00 60.75 ? 374 GLN A O 1 ATOM 2569 C CB . GLN A 1 376 ? 21.203 26.118 -29.635 1.00 60.57 ? 374 GLN A CB 1 ATOM 2570 C CG . GLN A 1 376 ? 20.335 25.155 -28.851 1.00 55.80 ? 374 GLN A CG 1 ATOM 2571 C CD . GLN A 1 376 ? 20.972 24.676 -27.590 1.00 64.91 ? 374 GLN A CD 1 ATOM 2572 O OE1 . GLN A 1 376 ? 20.765 25.240 -26.510 1.00 55.11 ? 374 GLN A OE1 1 ATOM 2573 N NE2 . GLN A 1 376 ? 21.738 23.600 -27.694 1.00 64.62 ? 374 GLN A NE2 1 ATOM 2574 N N . GLU A 1 377 ? 18.198 27.323 -30.796 1.00 53.61 ? 375 GLU A N 1 ATOM 2575 C CA . GLU A 1 377 ? 17.083 28.219 -30.575 1.00 52.13 ? 375 GLU A CA 1 ATOM 2576 C C . GLU A 1 377 ? 17.247 28.731 -29.164 1.00 55.70 ? 375 GLU A C 1 ATOM 2577 O O . GLU A 1 377 ? 17.532 27.942 -28.251 1.00 55.80 ? 375 GLU A O 1 ATOM 2578 C CB . GLU A 1 377 ? 15.751 27.463 -30.732 1.00 53.18 ? 375 GLU A CB 1 ATOM 2579 C CG . GLU A 1 377 ? 14.531 28.349 -30.911 1.00 56.44 ? 375 GLU A CG 1 ATOM 2580 C CD . GLU A 1 377 ? 14.076 29.140 -29.702 1.00 65.81 ? 375 GLU A CD 1 ATOM 2581 O OE1 . GLU A 1 377 ? 13.870 28.519 -28.632 1.00 52.09 ? 375 GLU A OE1 1 ATOM 2582 O OE2 . GLU A 1 377 ? 13.912 30.379 -29.832 1.00 53.45 ? 375 GLU A OE2 1 ATOM 2583 N N . SER A 1 378 ? 17.105 30.060 -29.001 1.00 50.43 ? 376 SER A N 1 ATOM 2584 C CA . SER A 1 378 ? 17.281 30.794 -27.754 1.00 49.61 ? 376 SER A CA 1 ATOM 2585 C C . SER A 1 378 ? 16.691 30.158 -26.519 1.00 51.79 ? 376 SER A C 1 ATOM 2586 O O . SER A 1 378 ? 17.311 30.272 -25.465 1.00 51.53 ? 376 SER A O 1 ATOM 2587 C CB . SER A 1 378 ? 16.746 32.216 -27.878 1.00 54.25 ? 376 SER A CB 1 ATOM 2588 O OG . SER A 1 378 ? 16.899 32.892 -26.638 1.00 66.14 ? 376 SER A OG 1 ATOM 2589 N N . LYS A 1 379 ? 15.500 29.530 -26.612 1.00 47.32 ? 377 LYS A N 1 ATOM 2590 C CA . LYS A 1 379 ? 14.846 29.009 -25.409 1.00 46.72 ? 377 LYS A CA 1 ATOM 2591 C C . LYS A 1 379 ? 14.936 27.486 -25.197 1.00 51.31 ? 377 LYS A C 1 ATOM 2592 O O . LYS A 1 379 ? 14.180 26.973 -24.365 1.00 51.85 ? 377 LYS A O 1 ATOM 2593 C CB . LYS A 1 379 ? 13.386 29.485 -25.351 1.00 47.23 ? 377 LYS A CB 1 ATOM 2594 C CG . LYS A 1 379 ? 13.289 30.933 -24.935 1.00 44.76 ? 377 LYS A CG 1 ATOM 2595 C CD . LYS A 1 379 ? 11.888 31.427 -24.954 1.00 45.85 ? 377 LYS A CD 1 ATOM 2596 C CE . LYS A 1 379 ? 11.846 32.888 -24.607 1.00 35.95 ? 377 LYS A CE 1 ATOM 2597 N NZ . LYS A 1 379 ? 11.355 33.690 -25.760 1.00 40.25 ? 377 LYS A NZ 1 ATOM 2598 N N . ILE A 1 380 ? 15.904 26.782 -25.845 1.00 46.66 ? 378 ILE A N 1 ATOM 2599 C CA . ILE A 1 380 ? 16.050 25.331 -25.656 1.00 46.45 ? 378 ILE A CA 1 ATOM 2600 C C . ILE A 1 380 ? 16.246 25.001 -24.170 1.00 49.08 ? 378 ILE A C 1 ATOM 2601 O O . ILE A 1 380 ? 15.569 24.110 -23.631 1.00 49.23 ? 378 ILE A O 1 ATOM 2602 C CB . ILE A 1 380 ? 17.133 24.685 -26.581 1.00 49.85 ? 378 ILE A CB 1 ATOM 2603 C CG1 . ILE A 1 380 ? 16.771 24.814 -28.098 1.00 49.95 ? 378 ILE A CG1 1 ATOM 2604 C CG2 . ILE A 1 380 ? 17.456 23.211 -26.184 1.00 49.94 ? 378 ILE A CG2 1 ATOM 2605 C CD1 . ILE A 1 380 ? 15.558 24.024 -28.625 1.00 58.89 ? 378 ILE A CD1 1 ATOM 2606 N N . MET A 1 381 ? 17.117 25.766 -23.502 1.00 42.56 ? 379 MET A N 1 ATOM 2607 C CA . MET A 1 381 ? 17.398 25.606 -22.078 1.00 41.36 ? 379 MET A CA 1 ATOM 2608 C C . MET A 1 381 ? 16.095 25.532 -21.301 1.00 44.74 ? 379 MET A C 1 ATOM 2609 O O . MET A 1 381 ? 15.830 24.518 -20.638 1.00 44.84 ? 379 MET A O 1 ATOM 2610 C CB . MET A 1 381 ? 18.290 26.757 -21.585 1.00 43.19 ? 379 MET A CB 1 ATOM 2611 C CG . MET A 1 381 ? 18.696 26.684 -20.135 1.00 45.90 ? 379 MET A CG 1 ATOM 2612 S SD . MET A 1 381 ? 19.429 28.292 -19.712 1.00 50.09 ? 379 MET A SD 1 ATOM 2613 C CE . MET A 1 381 ? 17.965 29.263 -19.405 1.00 46.75 ? 379 MET A CE 1 ATOM 2614 N N . PHE A 1 382 ? 15.232 26.547 -21.481 1.00 39.37 ? 380 PHE A N 1 ATOM 2615 C CA . PHE A 1 382 ? 13.954 26.604 -20.774 1.00 37.93 ? 380 PHE A CA 1 ATOM 2616 C C . PHE A 1 382 ? 13.024 25.387 -21.015 1.00 43.14 ? 380 PHE A C 1 ATOM 2617 O O . PHE A 1 382 ? 12.330 24.990 -20.091 1.00 43.90 ? 380 PHE A O 1 ATOM 2618 C CB . PHE A 1 382 ? 13.263 27.899 -21.078 1.00 38.48 ? 380 PHE A CB 1 ATOM 2619 C CG . PHE A 1 382 ? 14.041 29.144 -20.704 1.00 40.18 ? 380 PHE A CG 1 ATOM 2620 C CD1 . PHE A 1 382 ? 14.116 29.567 -19.381 1.00 42.59 ? 380 PHE A CD1 1 ATOM 2621 C CD2 . PHE A 1 382 ? 14.584 29.968 -21.687 1.00 41.83 ? 380 PHE A CD2 1 ATOM 2622 C CE1 . PHE A 1 382 ? 14.719 30.785 -19.049 1.00 41.97 ? 380 PHE A CE1 1 ATOM 2623 C CE2 . PHE A 1 382 ? 15.178 31.189 -21.353 1.00 42.91 ? 380 PHE A CE2 1 ATOM 2624 C CZ . PHE A 1 382 ? 15.239 31.585 -20.036 1.00 40.41 ? 380 PHE A CZ 1 ATOM 2625 N N . VAL A 1 383 ? 13.070 24.763 -22.206 1.00 40.26 ? 381 VAL A N 1 ATOM 2626 C CA . VAL A 1 383 ? 12.282 23.572 -22.584 1.00 40.96 ? 381 VAL A CA 1 ATOM 2627 C C . VAL A 1 383 ? 12.785 22.348 -21.780 1.00 46.72 ? 381 VAL A C 1 ATOM 2628 O O . VAL A 1 383 ? 11.981 21.627 -21.187 1.00 45.05 ? 381 VAL A O 1 ATOM 2629 C CB . VAL A 1 383 ? 12.326 23.321 -24.124 1.00 44.02 ? 381 VAL A CB 1 ATOM 2630 C CG1 . VAL A 1 383 ? 11.536 22.072 -24.530 1.00 43.60 ? 381 VAL A CG1 1 ATOM 2631 C CG2 . VAL A 1 383 ? 11.858 24.546 -24.895 1.00 43.29 ? 381 VAL A CG2 1 ATOM 2632 N N . VAL A 1 384 ? 14.126 22.157 -21.755 1.00 45.44 ? 382 VAL A N 1 ATOM 2633 C CA . VAL A 1 384 ? 14.846 21.100 -21.044 1.00 45.85 ? 382 VAL A CA 1 ATOM 2634 C C . VAL A 1 384 ? 14.582 21.266 -19.530 1.00 49.43 ? 382 VAL A C 1 ATOM 2635 O O . VAL A 1 384 ? 14.233 20.287 -18.856 1.00 49.93 ? 382 VAL A O 1 ATOM 2636 C CB . VAL A 1 384 ? 16.350 21.172 -21.444 1.00 51.09 ? 382 VAL A CB 1 ATOM 2637 C CG1 . VAL A 1 384 ? 17.271 20.529 -20.405 1.00 51.69 ? 382 VAL A CG1 1 ATOM 2638 C CG2 . VAL A 1 384 ? 16.579 20.553 -22.819 1.00 50.76 ? 382 VAL A CG2 1 ATOM 2639 N N . ASN A 1 385 ? 14.667 22.522 -19.033 1.00 44.52 ? 383 ASN A N 1 ATOM 2640 C CA . ASN A 1 385 ? 14.406 22.894 -17.639 1.00 43.55 ? 383 ASN A CA 1 ATOM 2641 C C . ASN A 1 385 ? 12.985 22.623 -17.200 1.00 46.66 ? 383 ASN A C 1 ATOM 2642 O O . ASN A 1 385 ? 12.791 22.200 -16.064 1.00 46.48 ? 383 ASN A O 1 ATOM 2643 C CB . ASN A 1 385 ? 14.788 24.351 -17.370 1.00 43.69 ? 383 ASN A CB 1 ATOM 2644 C CG . ASN A 1 385 ? 16.285 24.647 -17.382 1.00 55.63 ? 383 ASN A CG 1 ATOM 2645 O OD1 . ASN A 1 385 ? 17.115 23.861 -17.839 1.00 47.72 ? 383 ASN A OD1 1 ATOM 2646 N ND2 . ASN A 1 385 ? 16.670 25.805 -16.883 1.00 43.54 ? 383 ASN A ND2 1 ATOM 2647 N N . ALA A 1 386 ? 11.984 22.834 -18.080 1.00 43.12 ? 384 ALA A N 1 ATOM 2648 C CA . ALA A 1 386 ? 10.586 22.565 -17.705 1.00 42.39 ? 384 ALA A CA 1 ATOM 2649 C C . ALA A 1 386 ? 10.352 21.065 -17.532 1.00 45.35 ? 384 ALA A C 1 ATOM 2650 O O . ALA A 1 386 ? 9.734 20.653 -16.558 1.00 43.46 ? 384 ALA A O 1 ATOM 2651 C CB . ALA A 1 386 ? 9.631 23.134 -18.739 1.00 42.89 ? 384 ALA A CB 1 ATOM 2652 N N . VAL A 1 387 ? 10.885 20.253 -18.472 1.00 43.25 ? 385 VAL A N 1 ATOM 2653 C CA . VAL A 1 387 ? 10.778 18.791 -18.464 1.00 42.34 ? 385 VAL A CA 1 ATOM 2654 C C . VAL A 1 387 ? 11.392 18.260 -17.178 1.00 47.68 ? 385 VAL A C 1 ATOM 2655 O O . VAL A 1 387 ? 10.739 17.481 -16.475 1.00 47.16 ? 385 VAL A O 1 ATOM 2656 C CB . VAL A 1 387 ? 11.372 18.115 -19.736 1.00 44.15 ? 385 VAL A CB 1 ATOM 2657 C CG1 . VAL A 1 387 ? 11.145 16.601 -19.714 1.00 43.90 ? 385 VAL A CG1 1 ATOM 2658 C CG2 . VAL A 1 387 ? 10.771 18.699 -21.001 1.00 43.04 ? 385 VAL A CG2 1 ATOM 2659 N N . TYR A 1 388 ? 12.618 18.725 -16.846 1.00 45.36 ? 386 TYR A N 1 ATOM 2660 C CA . TYR A 1 388 ? 13.298 18.299 -15.619 1.00 45.43 ? 386 TYR A CA 1 ATOM 2661 C C . TYR A 1 388 ? 12.555 18.731 -14.389 1.00 48.09 ? 386 TYR A C 1 ATOM 2662 O O . TYR A 1 388 ? 12.363 17.898 -13.530 1.00 48.03 ? 386 TYR A O 1 ATOM 2663 C CB . TYR A 1 388 ? 14.767 18.722 -15.584 1.00 47.45 ? 386 TYR A CB 1 ATOM 2664 C CG . TYR A 1 388 ? 15.677 17.759 -16.315 1.00 50.77 ? 386 TYR A CG 1 ATOM 2665 C CD1 . TYR A 1 388 ? 15.777 17.780 -17.704 1.00 53.66 ? 386 TYR A CD1 1 ATOM 2666 C CD2 . TYR A 1 388 ? 16.445 16.828 -15.620 1.00 51.84 ? 386 TYR A CD2 1 ATOM 2667 C CE1 . TYR A 1 388 ? 16.628 16.905 -18.384 1.00 54.72 ? 386 TYR A CE1 1 ATOM 2668 C CE2 . TYR A 1 388 ? 17.299 15.947 -16.291 1.00 52.41 ? 386 TYR A CE2 1 ATOM 2669 C CZ . TYR A 1 388 ? 17.384 15.992 -17.672 1.00 58.62 ? 386 TYR A CZ 1 ATOM 2670 O OH . TYR A 1 388 ? 18.180 15.114 -18.344 1.00 61.97 ? 386 TYR A OH 1 ATOM 2671 N N . ALA A 1 389 ? 12.036 19.982 -14.343 1.00 44.16 ? 387 ALA A N 1 ATOM 2672 C CA . ALA A 1 389 ? 11.255 20.519 -13.219 1.00 42.88 ? 387 ALA A CA 1 ATOM 2673 C C . ALA A 1 389 ? 10.067 19.640 -12.877 1.00 45.05 ? 387 ALA A C 1 ATOM 2674 O O . ALA A 1 389 ? 9.832 19.354 -11.710 1.00 44.87 ? 387 ALA A O 1 ATOM 2675 C CB . ALA A 1 389 ? 10.799 21.928 -13.522 1.00 43.72 ? 387 ALA A CB 1 ATOM 2676 N N . MET A 1 390 ? 9.369 19.166 -13.896 1.00 41.79 ? 388 MET A N 1 ATOM 2677 C CA . MET A 1 390 ? 8.255 18.245 -13.776 1.00 41.52 ? 388 MET A CA 1 ATOM 2678 C C . MET A 1 390 ? 8.771 16.852 -13.348 1.00 44.83 ? 388 MET A C 1 ATOM 2679 O O . MET A 1 390 ? 8.095 16.209 -12.558 1.00 45.53 ? 388 MET A O 1 ATOM 2680 C CB . MET A 1 390 ? 7.516 18.145 -15.120 1.00 43.59 ? 388 MET A CB 1 ATOM 2681 C CG . MET A 1 390 ? 6.253 17.304 -15.041 1.00 46.35 ? 388 MET A CG 1 ATOM 2682 S SD . MET A 1 390 ? 4.874 18.246 -14.372 1.00 49.15 ? 388 MET A SD 1 ATOM 2683 C CE . MET A 1 390 ? 4.412 19.121 -15.806 1.00 45.82 ? 388 MET A CE 1 ATOM 2684 N N . ALA A 1 391 ? 9.932 16.378 -13.881 1.00 39.60 ? 389 ALA A N 1 ATOM 2685 C CA . ALA A 1 391 ? 10.518 15.062 -13.529 1.00 38.74 ? 389 ALA A CA 1 ATOM 2686 C C . ALA A 1 391 ? 10.981 15.041 -12.070 1.00 43.02 ? 389 ALA A C 1 ATOM 2687 O O . ALA A 1 391 ? 10.670 14.093 -11.351 1.00 41.99 ? 389 ALA A O 1 ATOM 2688 C CB . ALA A 1 391 ? 11.675 14.714 -14.453 1.00 39.11 ? 389 ALA A CB 1 ATOM 2689 N N . HIS A 1 392 ? 11.681 16.113 -11.621 1.00 39.64 ? 390 HIS A N 1 ATOM 2690 C CA . HIS A 1 392 ? 12.144 16.306 -10.245 1.00 38.78 ? 390 HIS A CA 1 ATOM 2691 C C . HIS A 1 392 ? 10.976 16.399 -9.306 1.00 45.76 ? 390 HIS A C 1 ATOM 2692 O O . HIS A 1 392 ? 11.034 15.812 -8.227 1.00 46.15 ? 390 HIS A O 1 ATOM 2693 C CB . HIS A 1 392 ? 13.014 17.542 -10.128 1.00 38.98 ? 390 HIS A CB 1 ATOM 2694 C CG . HIS A 1 392 ? 14.461 17.227 -10.353 1.00 42.91 ? 390 HIS A CG 1 ATOM 2695 N ND1 . HIS A 1 392 ? 14.958 16.965 -11.627 1.00 44.70 ? 390 HIS A ND1 1 ATOM 2696 C CD2 . HIS A 1 392 ? 15.463 17.079 -9.456 1.00 43.68 ? 390 HIS A CD2 1 ATOM 2697 C CE1 . HIS A 1 392 ? 16.245 16.712 -11.462 1.00 43.60 ? 390 HIS A CE1 1 ATOM 2698 N NE2 . HIS A 1 392 ? 16.588 16.753 -10.176 1.00 43.60 ? 390 HIS A NE2 1 ATOM 2699 N N . ALA A 1 393 ? 9.878 17.078 -9.739 1.00 42.39 ? 391 ALA A N 1 ATOM 2700 C CA . ALA A 1 393 ? 8.674 17.198 -8.939 1.00 41.57 ? 391 ALA A CA 1 ATOM 2701 C C . ALA A 1 393 ? 8.075 15.806 -8.745 1.00 45.43 ? 391 ALA A C 1 ATOM 2702 O O . ALA A 1 393 ? 7.693 15.446 -7.625 1.00 47.14 ? 391 ALA A O 1 ATOM 2703 C CB . ALA A 1 393 ? 7.688 18.114 -9.617 1.00 42.27 ? 391 ALA A CB 1 ATOM 2704 N N . LEU A 1 394 ? 8.082 14.990 -9.801 1.00 39.59 ? 392 LEU A N 1 ATOM 2705 C CA . LEU A 1 394 ? 7.554 13.621 -9.752 1.00 38.06 ? 392 LEU A CA 1 ATOM 2706 C C . LEU A 1 394 ? 8.455 12.724 -8.962 1.00 44.73 ? 392 LEU A C 1 ATOM 2707 O O . LEU A 1 394 ? 7.972 11.818 -8.294 1.00 45.72 ? 392 LEU A O 1 ATOM 2708 C CB . LEU A 1 394 ? 7.336 13.047 -11.155 1.00 36.54 ? 392 LEU A CB 1 ATOM 2709 C CG . LEU A 1 394 ? 6.163 13.586 -11.908 1.00 37.72 ? 392 LEU A CG 1 ATOM 2710 C CD1 . LEU A 1 394 ? 6.295 13.297 -13.407 1.00 36.68 ? 392 LEU A CD1 1 ATOM 2711 C CD2 . LEU A 1 394 ? 4.846 13.119 -11.294 1.00 33.97 ? 392 LEU A CD2 1 ATOM 2712 N N . HIS A 1 395 ? 9.757 13.003 -8.992 1.00 43.88 ? 393 HIS A N 1 ATOM 2713 C CA . HIS A 1 395 ? 10.741 12.235 -8.253 1.00 44.88 ? 393 HIS A CA 1 ATOM 2714 C C . HIS A 1 395 ? 10.562 12.453 -6.757 1.00 51.45 ? 393 HIS A C 1 ATOM 2715 O O . HIS A 1 395 ? 10.431 11.484 -6.021 1.00 53.45 ? 393 HIS A O 1 ATOM 2716 C CB . HIS A 1 395 ? 12.159 12.594 -8.698 1.00 46.03 ? 393 HIS A CB 1 ATOM 2717 C CG . HIS A 1 395 ? 13.183 11.699 -8.077 1.00 49.74 ? 393 HIS A CG 1 ATOM 2718 N ND1 . HIS A 1 395 ? 13.566 10.517 -8.683 1.00 51.23 ? 393 HIS A ND1 1 ATOM 2719 C CD2 . HIS A 1 395 ? 13.812 11.807 -6.882 1.00 51.29 ? 393 HIS A CD2 1 ATOM 2720 C CE1 . HIS A 1 395 ? 14.434 9.964 -7.857 1.00 50.67 ? 393 HIS A CE1 1 ATOM 2721 N NE2 . HIS A 1 395 ? 14.601 10.701 -6.754 1.00 51.08 ? 393 HIS A NE2 1 ATOM 2722 N N . ASN A 1 396 ? 10.538 13.718 -6.324 1.00 47.49 ? 394 ASN A N 1 ATOM 2723 C CA . ASN A 1 396 ? 10.377 14.121 -4.939 1.00 46.84 ? 394 ASN A CA 1 ATOM 2724 C C . ASN A 1 396 ? 9.032 13.665 -4.377 1.00 52.75 ? 394 ASN A C 1 ATOM 2725 O O . ASN A 1 396 ? 8.998 13.273 -3.205 1.00 54.26 ? 394 ASN A O 1 ATOM 2726 C CB . ASN A 1 396 ? 10.589 15.641 -4.779 1.00 44.15 ? 394 ASN A CB 1 ATOM 2727 C CG . ASN A 1 396 ? 11.913 16.180 -5.311 1.00 52.93 ? 394 ASN A CG 1 ATOM 2728 O OD1 . ASN A 1 396 ? 12.903 15.454 -5.520 1.00 39.83 ? 394 ASN A OD1 1 ATOM 2729 N ND2 . ASN A 1 396 ? 11.963 17.477 -5.559 1.00 40.57 ? 394 ASN A ND2 1 ATOM 2730 N N . MET A 1 397 ? 7.940 13.665 -5.207 1.00 48.99 ? 395 MET A N 1 ATOM 2731 C CA . MET A 1 397 ? 6.593 13.193 -4.794 1.00 48.21 ? 395 MET A CA 1 ATOM 2732 C C . MET A 1 397 ? 6.668 11.682 -4.585 1.00 50.98 ? 395 MET A C 1 ATOM 2733 O O . MET A 1 397 ? 6.112 11.174 -3.610 1.00 48.71 ? 395 MET A O 1 ATOM 2734 C CB . MET A 1 397 ? 5.485 13.549 -5.827 1.00 49.88 ? 395 MET A CB 1 ATOM 2735 C CG . MET A 1 397 ? 4.033 13.281 -5.338 1.00 52.09 ? 395 MET A CG 1 ATOM 2736 S SD . MET A 1 397 ? 2.818 13.627 -6.646 1.00 55.49 ? 395 MET A SD 1 ATOM 2737 C CE . MET A 1 397 ? 1.352 13.518 -5.828 1.00 51.55 ? 395 MET A CE 1 ATOM 2738 N N . HIS A 1 398 ? 7.389 10.977 -5.486 1.00 49.04 ? 396 HIS A N 1 ATOM 2739 C CA . HIS A 1 398 ? 7.597 9.527 -5.375 1.00 49.57 ? 396 HIS A CA 1 ATOM 2740 C C . HIS A 1 398 ? 8.321 9.175 -4.065 1.00 53.84 ? 396 HIS A C 1 ATOM 2741 O O . HIS A 1 398 ? 7.873 8.283 -3.366 1.00 54.25 ? 396 HIS A O 1 ATOM 2742 C CB . HIS A 1 398 ? 8.363 8.975 -6.584 1.00 50.29 ? 396 HIS A CB 1 ATOM 2743 C CG . HIS A 1 398 ? 8.474 7.483 -6.574 1.00 53.95 ? 396 HIS A CG 1 ATOM 2744 N ND1 . HIS A 1 398 ? 9.586 6.844 -6.038 1.00 55.74 ? 396 HIS A ND1 1 ATOM 2745 C CD2 . HIS A 1 398 ? 7.608 6.546 -7.026 1.00 55.34 ? 396 HIS A CD2 1 ATOM 2746 C CE1 . HIS A 1 398 ? 9.354 5.550 -6.177 1.00 54.96 ? 396 HIS A CE1 1 ATOM 2747 N NE2 . HIS A 1 398 ? 8.185 5.323 -6.776 1.00 55.13 ? 396 HIS A NE2 1 ATOM 2748 N N . ARG A 1 399 ? 9.396 9.900 -3.717 1.00 49.17 ? 397 ARG A N 1 ATOM 2749 C CA . ARG A 1 399 ? 10.144 9.691 -2.486 1.00 49.29 ? 397 ARG A CA 1 ATOM 2750 C C . ARG A 1 399 ? 9.245 9.768 -1.261 1.00 52.31 ? 397 ARG A C 1 ATOM 2751 O O . ARG A 1 399 ? 9.346 8.914 -0.380 1.00 53.08 ? 397 ARG A O 1 ATOM 2752 C CB . ARG A 1 399 ? 11.281 10.717 -2.366 1.00 53.05 ? 397 ARG A CB 1 ATOM 2753 C CG . ARG A 1 399 ? 12.510 10.211 -1.612 1.00 71.34 ? 397 ARG A CG 1 ATOM 2754 C CD . ARG A 1 399 ? 13.695 11.148 -1.791 1.00 90.98 ? 397 ARG A CD 1 ATOM 2755 N NE . ARG A 1 399 ? 14.859 10.739 -0.998 1.00 105.99 ? 397 ARG A NE 1 ATOM 2756 C CZ . ARG A 1 399 ? 16.073 10.518 -1.495 1.00 122.63 ? 397 ARG A CZ 1 ATOM 2757 N NH1 . ARG A 1 399 ? 16.304 10.662 -2.796 1.00 111.57 ? 397 ARG A NH1 1 ATOM 2758 N NH2 . ARG A 1 399 ? 17.067 10.153 -0.694 1.00 107.17 ? 397 ARG A NH2 1 ATOM 2759 N N . ALA A 1 400 ? 8.356 10.765 -1.216 1.00 47.29 ? 398 ALA A N 1 ATOM 2760 C CA . ALA A 1 400 ? 7.439 10.981 -0.100 1.00 46.13 ? 398 ALA A CA 1 ATOM 2761 C C . ALA A 1 400 ? 6.312 9.945 0.012 1.00 49.46 ? 398 ALA A C 1 ATOM 2762 O O . ALA A 1 400 ? 6.105 9.366 1.078 1.00 48.44 ? 398 ALA A O 1 ATOM 2763 C CB . ALA A 1 400 ? 6.853 12.380 -0.178 1.00 46.36 ? 398 ALA A CB 1 ATOM 2764 N N . LEU A 1 401 ? 5.578 9.746 -1.071 1.00 47.88 ? 399 LEU A N 1 ATOM 2765 C CA . LEU A 1 401 ? 4.393 8.900 -1.133 1.00 49.29 ? 399 LEU A CA 1 ATOM 2766 C C . LEU A 1 401 ? 4.663 7.420 -1.330 1.00 57.68 ? 399 LEU A C 1 ATOM 2767 O O . LEU A 1 401 ? 3.841 6.592 -0.918 1.00 58.53 ? 399 LEU A O 1 ATOM 2768 C CB . LEU A 1 401 ? 3.437 9.422 -2.233 1.00 49.17 ? 399 LEU A CB 1 ATOM 2769 C CG . LEU A 1 401 ? 2.893 10.865 -2.041 1.00 53.54 ? 399 LEU A CG 1 ATOM 2770 C CD1 . LEU A 1 401 ? 1.786 11.164 -3.007 1.00 53.60 ? 399 LEU A CD1 1 ATOM 2771 C CD2 . LEU A 1 401 ? 2.340 11.058 -0.667 1.00 55.54 ? 399 LEU A CD2 1 ATOM 2772 N N . CYS A 1 402 ? 5.777 7.086 -1.997 1.00 55.32 ? 400 CYS A N 1 ATOM 2773 C CA . CYS A 1 402 ? 6.169 5.718 -2.299 1.00 55.76 ? 400 CYS A CA 1 ATOM 2774 C C . CYS A 1 402 ? 7.494 5.401 -1.586 1.00 60.35 ? 400 CYS A C 1 ATOM 2775 O O . CYS A 1 402 ? 8.512 5.203 -2.263 1.00 58.52 ? 400 CYS A O 1 ATOM 2776 C CB . CYS A 1 402 ? 6.270 5.515 -3.810 1.00 56.51 ? 400 CYS A CB 1 ATOM 2777 S SG . CYS A 1 402 ? 4.732 5.846 -4.719 1.00 61.01 ? 400 CYS A SG 1 ATOM 2778 N N . PRO A 1 403 ? 7.507 5.340 -0.222 1.00 58.71 ? 401 PRO A N 1 ATOM 2779 C CA . PRO A 1 403 ? 8.774 5.097 0.490 1.00 59.33 ? 401 PRO A CA 1 ATOM 2780 C C . PRO A 1 403 ? 9.555 3.849 0.104 1.00 64.52 ? 401 PRO A C 1 ATOM 2781 O O . PRO A 1 403 ? 10.732 3.978 -0.239 1.00 64.57 ? 401 PRO A O 1 ATOM 2782 C CB . PRO A 1 403 ? 8.357 5.048 1.972 1.00 60.59 ? 401 PRO A CB 1 ATOM 2783 C CG . PRO A 1 403 ? 6.903 4.863 1.966 1.00 64.30 ? 401 PRO A CG 1 ATOM 2784 C CD . PRO A 1 403 ? 6.413 5.554 0.744 1.00 59.87 ? 401 PRO A CD 1 ATOM 2785 N N . ASN A 1 404 ? 8.917 2.667 0.155 1.00 61.07 ? 402 ASN A N 1 ATOM 2786 C CA . ASN A 1 404 ? 9.582 1.388 -0.065 1.00 62.07 ? 402 ASN A CA 1 ATOM 2787 C C . ASN A 1 404 ? 10.140 1.157 -1.473 1.00 67.28 ? 402 ASN A C 1 ATOM 2788 O O . ASN A 1 404 ? 11.350 0.953 -1.598 1.00 69.17 ? 402 ASN A O 1 ATOM 2789 C CB . ASN A 1 404 ? 8.668 0.217 0.340 1.00 69.75 ? 402 ASN A CB 1 ATOM 2790 C CG . ASN A 1 404 ? 8.150 0.271 1.768 1.00 100.28 ? 402 ASN A CG 1 ATOM 2791 O OD1 . ASN A 1 404 ? 8.910 0.411 2.744 1.00 93.47 ? 402 ASN A OD1 1 ATOM 2792 N ND2 . ASN A 1 404 ? 6.838 0.123 1.920 1.00 92.64 ? 402 ASN A ND2 1 ATOM 2793 N N . THR A 1 405 ? 9.279 1.159 -2.515 1.00 62.02 ? 403 THR A N 1 ATOM 2794 C CA . THR A 1 405 ? 9.626 0.847 -3.914 1.00 60.82 ? 403 THR A CA 1 ATOM 2795 C C . THR A 1 405 ? 10.244 2.015 -4.759 1.00 63.20 ? 403 THR A C 1 ATOM 2796 O O . THR A 1 405 ? 10.399 3.140 -4.272 1.00 62.76 ? 403 THR A O 1 ATOM 2797 C CB . THR A 1 405 ? 8.379 0.263 -4.603 1.00 68.17 ? 403 THR A CB 1 ATOM 2798 O OG1 . THR A 1 405 ? 8.700 -0.163 -5.932 1.00 67.60 ? 403 THR A OG1 1 ATOM 2799 C CG2 . THR A 1 405 ? 7.172 1.224 -4.600 1.00 68.19 ? 403 THR A CG2 1 ATOM 2800 N N . THR A 1 406 ? 10.640 1.685 -6.022 1.00 58.17 ? 404 THR A N 1 ATOM 2801 C CA . THR A 1 406 ? 11.137 2.585 -7.070 1.00 56.61 ? 404 THR A CA 1 ATOM 2802 C C . THR A 1 406 ? 10.102 2.642 -8.197 1.00 58.94 ? 404 THR A C 1 ATOM 2803 O O . THR A 1 406 ? 10.261 3.427 -9.131 1.00 60.16 ? 404 THR A O 1 ATOM 2804 C CB . THR A 1 406 ? 12.488 2.156 -7.658 1.00 60.95 ? 404 THR A CB 1 ATOM 2805 O OG1 . THR A 1 406 ? 12.332 0.943 -8.414 1.00 56.70 ? 404 THR A OG1 1 ATOM 2806 C CG2 . THR A 1 406 ? 13.602 2.075 -6.619 1.00 57.97 ? 404 THR A CG2 1 ATOM 2807 N N . ARG A 1 407 ? 9.069 1.796 -8.130 1.00 52.67 ? 405 ARG A N 1 ATOM 2808 C CA . ARG A 1 407 ? 7.998 1.766 -9.122 1.00 52.27 ? 405 ARG A CA 1 ATOM 2809 C C . ARG A 1 407 ? 6.837 2.626 -8.621 1.00 55.72 ? 405 ARG A C 1 ATOM 2810 O O . ARG A 1 407 ? 6.878 3.064 -7.475 1.00 55.98 ? 405 ARG A O 1 ATOM 2811 C CB . ARG A 1 407 ? 7.562 0.314 -9.414 1.00 54.47 ? 405 ARG A CB 1 ATOM 2812 C CG . ARG A 1 407 ? 8.700 -0.579 -9.934 1.00 76.82 ? 405 ARG A CG 1 ATOM 2813 C CD . ARG A 1 407 ? 8.966 -0.437 -11.432 1.00 98.63 ? 405 ARG A CD 1 ATOM 2814 N NE . ARG A 1 407 ? 10.394 -0.312 -11.752 1.00 113.36 ? 405 ARG A NE 1 ATOM 2815 C CZ . ARG A 1 407 ? 11.220 -1.338 -11.950 1.00 130.77 ? 405 ARG A CZ 1 ATOM 2816 N NH1 . ARG A 1 407 ? 10.780 -2.587 -11.838 1.00 120.76 ? 405 ARG A NH1 1 ATOM 2817 N NH2 . ARG A 1 407 ? 12.497 -1.122 -12.245 1.00 115.30 ? 405 ARG A NH2 1 ATOM 2818 N N . LEU A 1 408 ? 5.825 2.908 -9.461 1.00 51.72 ? 406 LEU A N 1 ATOM 2819 C CA . LEU A 1 408 ? 4.688 3.724 -9.014 1.00 50.97 ? 406 LEU A CA 1 ATOM 2820 C C . LEU A 1 408 ? 3.859 2.949 -8.051 1.00 52.45 ? 406 LEU A C 1 ATOM 2821 O O . LEU A 1 408 ? 3.210 1.982 -8.462 1.00 49.74 ? 406 LEU A O 1 ATOM 2822 C CB . LEU A 1 408 ? 3.754 4.107 -10.171 1.00 51.17 ? 406 LEU A CB 1 ATOM 2823 C CG . LEU A 1 408 ? 4.162 5.151 -11.151 1.00 55.78 ? 406 LEU A CG 1 ATOM 2824 C CD1 . LEU A 1 408 ? 3.165 5.159 -12.289 1.00 55.90 ? 406 LEU A CD1 1 ATOM 2825 C CD2 . LEU A 1 408 ? 4.252 6.529 -10.482 1.00 57.93 ? 406 LEU A CD2 1 ATOM 2826 N N . CYS A 1 409 ? 3.816 3.402 -6.793 1.00 51.97 ? 407 CYS A N 1 ATOM 2827 C CA . CYS A 1 409 ? 2.993 2.789 -5.754 1.00 53.91 ? 407 CYS A CA 1 ATOM 2828 C C . CYS A 1 409 ? 1.514 3.257 -5.882 1.00 60.23 ? 407 CYS A C 1 ATOM 2829 O O . CYS A 1 409 ? 1.227 4.126 -6.715 1.00 61.05 ? 407 CYS A O 1 ATOM 2830 C CB . CYS A 1 409 ? 3.573 3.060 -4.373 1.00 55.74 ? 407 CYS A CB 1 ATOM 2831 S SG . CYS A 1 409 ? 3.303 4.749 -3.766 1.00 61.14 ? 407 CYS A SG 1 ATOM 2832 N N . ASP A 1 410 ? 0.576 2.667 -5.091 1.00 56.85 ? 408 ASP A N 1 ATOM 2833 C CA . ASP A 1 410 ? -0.863 2.979 -5.138 1.00 56.18 ? 408 ASP A CA 1 ATOM 2834 C C . ASP A 1 410 ? -1.175 4.459 -4.964 1.00 58.60 ? 408 ASP A C 1 ATOM 2835 O O . ASP A 1 410 ? -2.007 5.003 -5.703 1.00 57.86 ? 408 ASP A O 1 ATOM 2836 C CB . ASP A 1 410 ? -1.657 2.133 -4.135 1.00 58.36 ? 408 ASP A CB 1 ATOM 2837 C CG . ASP A 1 410 ? -1.626 0.626 -4.368 1.00 69.13 ? 408 ASP A CG 1 ATOM 2838 O OD1 . ASP A 1 410 ? -1.652 0.201 -5.552 1.00 67.96 ? 408 ASP A OD1 1 ATOM 2839 O OD2 . ASP A 1 410 ? -1.636 -0.130 -3.363 1.00 76.59 ? 408 ASP A OD2 1 ATOM 2840 N N . ALA A 1 411 ? -0.441 5.121 -4.046 1.00 53.43 ? 409 ALA A N 1 ATOM 2841 C CA . ALA A 1 411 ? -0.539 6.553 -3.767 1.00 52.55 ? 409 ALA A CA 1 ATOM 2842 C C . ALA A 1 411 ? -0.327 7.456 -5.006 1.00 56.72 ? 409 ALA A C 1 ATOM 2843 O O . ALA A 1 411 ? -0.782 8.606 -4.994 1.00 58.25 ? 409 ALA A O 1 ATOM 2844 C CB . ALA A 1 411 ? 0.430 6.932 -2.665 1.00 53.14 ? 409 ALA A CB 1 ATOM 2845 N N . MET A 1 412 ? 0.325 6.952 -6.072 1.00 50.89 ? 410 MET A N 1 ATOM 2846 C CA . MET A 1 412 ? 0.525 7.772 -7.274 1.00 50.16 ? 410 MET A CA 1 ATOM 2847 C C . MET A 1 412 ? -0.172 7.192 -8.519 1.00 55.16 ? 410 MET A C 1 ATOM 2848 O O . MET A 1 412 ? 0.184 7.540 -9.647 1.00 55.45 ? 410 MET A O 1 ATOM 2849 C CB . MET A 1 412 ? 2.001 8.083 -7.533 1.00 51.77 ? 410 MET A CB 1 ATOM 2850 C CG . MET A 1 412 ? 2.637 8.967 -6.468 1.00 55.41 ? 410 MET A CG 1 ATOM 2851 S SD . MET A 1 412 ? 4.126 9.884 -6.991 1.00 60.39 ? 410 MET A SD 1 ATOM 2852 C CE . MET A 1 412 ? 4.948 8.690 -7.917 1.00 57.87 ? 410 MET A CE 1 ATOM 2853 N N . ARG A 1 413 ? -1.210 6.369 -8.305 1.00 51.18 ? 411 ARG A N 1 ATOM 2854 C CA . ARG A 1 413 ? -2.037 5.778 -9.370 1.00 51.08 ? 411 ARG A CA 1 ATOM 2855 C C . ARG A 1 413 ? -3.489 6.192 -9.052 1.00 52.93 ? 411 ARG A C 1 ATOM 2856 O O . ARG A 1 413 ? -4.159 5.495 -8.297 1.00 53.87 ? 411 ARG A O 1 ATOM 2857 C CB . ARG A 1 413 ? -1.890 4.222 -9.419 1.00 51.46 ? 411 ARG A CB 1 ATOM 2858 C CG . ARG A 1 413 ? -0.459 3.708 -9.649 1.00 54.49 ? 411 ARG A CG 1 ATOM 2859 C CD . ARG A 1 413 ? -0.363 2.182 -9.643 1.00 55.15 ? 411 ARG A CD 1 ATOM 2860 N NE . ARG A 1 413 ? 0.939 1.732 -10.145 1.00 67.17 ? 411 ARG A NE 1 ATOM 2861 C CZ . ARG A 1 413 ? 1.209 1.506 -11.434 1.00 86.75 ? 411 ARG A CZ 1 ATOM 2862 N NH1 . ARG A 1 413 ? 0.258 1.634 -12.352 1.00 73.55 ? 411 ARG A NH1 1 ATOM 2863 N NH2 . ARG A 1 413 ? 2.430 1.136 -11.810 1.00 69.41 ? 411 ARG A NH2 1 ATOM 2864 N N . PRO A 1 414 ? -3.972 7.372 -9.490 1.00 47.74 ? 412 PRO A N 1 ATOM 2865 C CA . PRO A 1 414 ? -3.300 8.381 -10.337 1.00 46.36 ? 412 PRO A CA 1 ATOM 2866 C C . PRO A 1 414 ? -2.525 9.375 -9.503 1.00 45.47 ? 412 PRO A C 1 ATOM 2867 O O . PRO A 1 414 ? -2.587 9.364 -8.278 1.00 46.70 ? 412 PRO A O 1 ATOM 2868 C CB . PRO A 1 414 ? -4.477 9.038 -11.086 1.00 47.85 ? 412 PRO A CB 1 ATOM 2869 C CG . PRO A 1 414 ? -5.690 8.853 -10.182 1.00 52.07 ? 412 PRO A CG 1 ATOM 2870 C CD . PRO A 1 414 ? -5.343 7.806 -9.133 1.00 48.34 ? 412 PRO A CD 1 ATOM 2871 N N . VAL A 1 415 ? -1.758 10.194 -10.147 1.00 39.17 ? 413 VAL A N 1 ATOM 2872 C CA . VAL A 1 415 ? -1.003 11.226 -9.431 1.00 38.04 ? 413 VAL A CA 1 ATOM 2873 C C . VAL A 1 415 ? -2.005 12.372 -9.114 1.00 42.65 ? 413 VAL A C 1 ATOM 2874 O O . VAL A 1 415 ? -2.712 12.825 -10.014 1.00 41.83 ? 413 VAL A O 1 ATOM 2875 C CB . VAL A 1 415 ? 0.213 11.677 -10.287 1.00 40.13 ? 413 VAL A CB 1 ATOM 2876 C CG1 . VAL A 1 415 ? 0.915 12.883 -9.705 1.00 39.38 ? 413 VAL A CG1 1 ATOM 2877 C CG2 . VAL A 1 415 ? 1.196 10.537 -10.453 1.00 39.77 ? 413 VAL A CG2 1 ATOM 2878 N N . ASN A 1 416 ? -2.122 12.778 -7.839 1.00 40.03 ? 414 ASN A N 1 ATOM 2879 C CA . ASN A 1 416 ? -3.029 13.878 -7.484 1.00 39.71 ? 414 ASN A CA 1 ATOM 2880 C C . ASN A 1 416 ? -2.338 15.172 -7.926 1.00 42.02 ? 414 ASN A C 1 ATOM 2881 O O . ASN A 1 416 ? -1.317 15.548 -7.348 1.00 41.01 ? 414 ASN A O 1 ATOM 2882 C CB . ASN A 1 416 ? -3.349 13.867 -5.973 1.00 40.50 ? 414 ASN A CB 1 ATOM 2883 C CG . ASN A 1 416 ? -4.076 15.078 -5.408 1.00 63.68 ? 414 ASN A CG 1 ATOM 2884 O OD1 . ASN A 1 416 ? -3.882 16.226 -5.806 1.00 56.14 ? 414 ASN A OD1 1 ATOM 2885 N ND2 . ASN A 1 416 ? -4.871 14.857 -4.391 1.00 58.37 ? 414 ASN A ND2 1 ATOM 2886 N N . GLY A 1 417 ? -2.877 15.790 -8.973 1.00 38.35 ? 415 GLY A N 1 ATOM 2887 C CA . GLY A 1 417 ? -2.381 17.033 -9.560 1.00 38.31 ? 415 GLY A CA 1 ATOM 2888 C C . GLY A 1 417 ? -2.278 18.221 -8.620 1.00 41.54 ? 415 GLY A C 1 ATOM 2889 O O . GLY A 1 417 ? -1.320 18.996 -8.715 1.00 39.81 ? 415 GLY A O 1 ATOM 2890 N N . ARG A 1 418 ? -3.252 18.360 -7.685 1.00 38.96 ? 416 ARG A N 1 ATOM 2891 C CA . ARG A 1 418 ? -3.282 19.447 -6.699 1.00 38.76 ? 416 ARG A CA 1 ATOM 2892 C C . ARG A 1 418 ? -2.072 19.310 -5.771 1.00 43.50 ? 416 ARG A C 1 ATOM 2893 O O . ARG A 1 418 ? -1.278 20.248 -5.629 1.00 44.25 ? 416 ARG A O 1 ATOM 2894 C CB . ARG A 1 418 ? -4.623 19.463 -5.947 1.00 40.33 ? 416 ARG A CB 1 ATOM 2895 C CG . ARG A 1 418 ? -4.853 20.704 -5.088 1.00 56.53 ? 416 ARG A CG 1 ATOM 2896 C CD . ARG A 1 418 ? -6.114 20.577 -4.257 1.00 73.35 ? 416 ARG A CD 1 ATOM 2897 N NE . ARG A 1 418 ? -6.432 21.811 -3.530 1.00 90.82 ? 416 ARG A NE 1 ATOM 2898 C CZ . ARG A 1 418 ? -7.306 22.722 -3.947 1.00 108.97 ? 416 ARG A CZ 1 ATOM 2899 N NH1 . ARG A 1 418 ? -7.948 22.559 -5.099 1.00 106.25 ? 416 ARG A NH1 1 ATOM 2900 N NH2 . ARG A 1 418 ? -7.543 23.806 -3.218 1.00 87.21 ? 416 ARG A NH2 1 ATOM 2901 N N . ARG A 1 419 ? -1.869 18.099 -5.249 1.00 39.72 ? 417 ARG A N 1 ATOM 2902 C CA . ARG A 1 419 ? -0.719 17.726 -4.445 1.00 38.66 ? 417 ARG A CA 1 ATOM 2903 C C . ARG A 1 419 ? 0.579 17.969 -5.224 1.00 41.69 ? 417 ARG A C 1 ATOM 2904 O O . ARG A 1 419 ? 1.395 18.778 -4.788 1.00 42.86 ? 417 ARG A O 1 ATOM 2905 C CB . ARG A 1 419 ? -0.836 16.261 -4.025 1.00 38.16 ? 417 ARG A CB 1 ATOM 2906 C CG . ARG A 1 419 ? 0.205 15.878 -2.998 1.00 46.12 ? 417 ARG A CG 1 ATOM 2907 C CD . ARG A 1 419 ? -0.283 16.098 -1.581 1.00 47.49 ? 417 ARG A CD 1 ATOM 2908 N NE . ARG A 1 419 ? 0.733 15.648 -0.637 1.00 52.95 ? 417 ARG A NE 1 ATOM 2909 C CZ . ARG A 1 419 ? 0.825 14.407 -0.168 1.00 63.85 ? 417 ARG A CZ 1 ATOM 2910 N NH1 . ARG A 1 419 ? -0.069 13.484 -0.521 1.00 42.86 ? 417 ARG A NH1 1 ATOM 2911 N NH2 . ARG A 1 419 ? 1.803 14.080 0.666 1.00 50.32 ? 417 ARG A NH2 1 ATOM 2912 N N . LEU A 1 420 ? 0.735 17.326 -6.386 1.00 37.41 ? 418 LEU A N 1 ATOM 2913 C CA . LEU A 1 420 ? 1.893 17.450 -7.274 1.00 37.92 ? 418 LEU A CA 1 ATOM 2914 C C . LEU A 1 420 ? 2.350 18.923 -7.498 1.00 45.37 ? 418 LEU A C 1 ATOM 2915 O O . LEU A 1 420 ? 3.541 19.213 -7.393 1.00 47.12 ? 418 LEU A O 1 ATOM 2916 C CB . LEU A 1 420 ? 1.610 16.744 -8.630 1.00 37.28 ? 418 LEU A CB 1 ATOM 2917 C CG . LEU A 1 420 ? 2.601 16.954 -9.815 1.00 41.24 ? 418 LEU A CG 1 ATOM 2918 C CD1 . LEU A 1 420 ? 4.067 16.501 -9.467 1.00 41.34 ? 418 LEU A CD1 1 ATOM 2919 C CD2 . LEU A 1 420 ? 2.100 16.260 -11.085 1.00 40.37 ? 418 LEU A CD2 1 ATOM 2920 N N . TYR A 1 421 ? 1.417 19.823 -7.818 1.00 40.71 ? 419 TYR A N 1 ATOM 2921 C CA . TYR A 1 421 ? 1.718 21.221 -8.113 1.00 39.54 ? 419 TYR A CA 1 ATOM 2922 C C . TYR A 1 421 ? 2.080 22.020 -6.869 1.00 42.06 ? 419 TYR A C 1 ATOM 2923 O O . TYR A 1 421 ? 3.154 22.613 -6.813 1.00 39.99 ? 419 TYR A O 1 ATOM 2924 C CB . TYR A 1 421 ? 0.550 21.870 -8.902 1.00 40.98 ? 419 TYR A CB 1 ATOM 2925 C CG . TYR A 1 421 ? 0.785 23.328 -9.219 1.00 44.22 ? 419 TYR A CG 1 ATOM 2926 C CD1 . TYR A 1 421 ? 1.512 23.710 -10.345 1.00 46.14 ? 419 TYR A CD1 1 ATOM 2927 C CD2 . TYR A 1 421 ? 0.343 24.328 -8.356 1.00 45.62 ? 419 TYR A CD2 1 ATOM 2928 C CE1 . TYR A 1 421 ? 1.809 25.052 -10.591 1.00 47.57 ? 419 TYR A CE1 1 ATOM 2929 C CE2 . TYR A 1 421 ? 0.644 25.668 -8.587 1.00 46.52 ? 419 TYR A CE2 1 ATOM 2930 C CZ . TYR A 1 421 ? 1.360 26.026 -9.712 1.00 52.42 ? 419 TYR A CZ 1 ATOM 2931 O OH . TYR A 1 421 ? 1.644 27.348 -9.904 1.00 52.51 ? 419 TYR A OH 1 ATOM 2932 N N . LYS A 1 422 ? 1.175 22.031 -5.872 1.00 40.64 ? 420 LYS A N 1 ATOM 2933 C CA . LYS A 1 422 ? 1.304 22.794 -4.628 1.00 39.96 ? 420 LYS A CA 1 ATOM 2934 C C . LYS A 1 422 ? 2.454 22.344 -3.736 1.00 42.51 ? 420 LYS A C 1 ATOM 2935 O O . LYS A 1 422 ? 3.142 23.186 -3.175 1.00 42.50 ? 420 LYS A O 1 ATOM 2936 C CB . LYS A 1 422 ? -0.032 22.802 -3.866 1.00 42.23 ? 420 LYS A CB 1 ATOM 2937 C CG . LYS A 1 422 ? -0.145 23.875 -2.788 1.00 64.42 ? 420 LYS A CG 1 ATOM 2938 C CD . LYS A 1 422 ? -0.750 25.173 -3.326 1.00 79.94 ? 420 LYS A CD 1 ATOM 2939 C CE . LYS A 1 422 ? -0.379 26.371 -2.476 1.00 83.12 ? 420 LYS A CE 1 ATOM 2940 N NZ . LYS A 1 422 ? -0.724 27.647 -3.154 1.00 81.16 ? 420 LYS A NZ 1 ATOM 2941 N N . ASP A 1 423 ? 2.678 21.029 -3.612 1.00 39.06 ? 421 ASP A N 1 ATOM 2942 C CA . ASP A 1 423 ? 3.705 20.493 -2.733 1.00 37.56 ? 421 ASP A CA 1 ATOM 2943 C C . ASP A 1 423 ? 5.018 20.132 -3.415 1.00 41.62 ? 421 ASP A C 1 ATOM 2944 O O . ASP A 1 423 ? 6.052 20.108 -2.748 1.00 41.42 ? 421 ASP A O 1 ATOM 2945 C CB . ASP A 1 423 ? 3.138 19.287 -1.973 1.00 39.23 ? 421 ASP A CB 1 ATOM 2946 C CG . ASP A 1 423 ? 2.142 19.592 -0.853 1.00 54.64 ? 421 ASP A CG 1 ATOM 2947 O OD1 . ASP A 1 423 ? 2.027 20.788 -0.451 1.00 55.88 ? 421 ASP A OD1 1 ATOM 2948 O OD2 . ASP A 1 423 ? 1.502 18.635 -0.350 1.00 58.32 ? 421 ASP A OD2 1 ATOM 2949 N N . PHE A 1 424 ? 5.010 19.823 -4.709 1.00 39.86 ? 422 PHE A N 1 ATOM 2950 C CA . PHE A 1 424 ? 6.266 19.386 -5.313 1.00 41.39 ? 422 PHE A CA 1 ATOM 2951 C C . PHE A 1 424 ? 6.740 20.310 -6.399 1.00 46.31 ? 422 PHE A C 1 ATOM 2952 O O . PHE A 1 424 ? 7.829 20.860 -6.232 1.00 47.94 ? 422 PHE A O 1 ATOM 2953 C CB . PHE A 1 424 ? 6.211 17.892 -5.754 1.00 43.79 ? 422 PHE A CB 1 ATOM 2954 C CG . PHE A 1 424 ? 5.917 17.036 -4.531 1.00 44.85 ? 422 PHE A CG 1 ATOM 2955 C CD1 . PHE A 1 424 ? 6.930 16.718 -3.626 1.00 48.21 ? 422 PHE A CD1 1 ATOM 2956 C CD2 . PHE A 1 424 ? 4.608 16.715 -4.188 1.00 44.51 ? 422 PHE A CD2 1 ATOM 2957 C CE1 . PHE A 1 424 ? 6.645 16.043 -2.438 1.00 48.37 ? 422 PHE A CE1 1 ATOM 2958 C CE2 . PHE A 1 424 ? 4.321 16.069 -2.992 1.00 47.29 ? 422 PHE A CE2 1 ATOM 2959 C CZ . PHE A 1 424 ? 5.339 15.734 -2.125 1.00 46.61 ? 422 PHE A CZ 1 ATOM 2960 N N . VAL A 1 425 ? 5.925 20.590 -7.426 1.00 42.39 ? 423 VAL A N 1 ATOM 2961 C CA . VAL A 1 425 ? 6.318 21.499 -8.530 1.00 42.20 ? 423 VAL A CA 1 ATOM 2962 C C . VAL A 1 425 ? 6.829 22.837 -7.980 1.00 47.15 ? 423 VAL A C 1 ATOM 2963 O O . VAL A 1 425 ? 7.929 23.259 -8.341 1.00 49.10 ? 423 VAL A O 1 ATOM 2964 C CB . VAL A 1 425 ? 5.247 21.696 -9.658 1.00 44.41 ? 423 VAL A CB 1 ATOM 2965 C CG1 . VAL A 1 425 ? 5.653 22.819 -10.613 1.00 44.07 ? 423 VAL A CG1 1 ATOM 2966 C CG2 . VAL A 1 425 ? 4.990 20.401 -10.436 1.00 43.10 ? 423 VAL A CG2 1 ATOM 2967 N N . LEU A 1 426 ? 6.087 23.445 -7.052 1.00 41.60 ? 424 LEU A N 1 ATOM 2968 C CA . LEU A 1 426 ? 6.481 24.735 -6.496 1.00 41.29 ? 424 LEU A CA 1 ATOM 2969 C C . LEU A 1 426 ? 7.728 24.682 -5.607 1.00 45.64 ? 424 LEU A C 1 ATOM 2970 O O . LEU A 1 426 ? 8.352 25.727 -5.372 1.00 43.06 ? 424 LEU A O 1 ATOM 2971 C CB . LEU A 1 426 ? 5.306 25.381 -5.734 1.00 41.25 ? 424 LEU A CB 1 ATOM 2972 C CG . LEU A 1 426 ? 4.081 25.858 -6.528 1.00 44.76 ? 424 LEU A CG 1 ATOM 2973 C CD1 . LEU A 1 426 ? 3.079 26.436 -5.611 1.00 43.13 ? 424 LEU A CD1 1 ATOM 2974 C CD2 . LEU A 1 426 ? 4.458 26.924 -7.535 1.00 50.00 ? 424 LEU A CD2 1 ATOM 2975 N N . ASN A 1 427 ? 8.096 23.471 -5.119 1.00 44.02 ? 425 ASN A N 1 ATOM 2976 C CA . ASN A 1 427 ? 9.230 23.324 -4.189 1.00 44.53 ? 425 ASN A CA 1 ATOM 2977 C C . ASN A 1 427 ? 10.467 22.655 -4.773 1.00 49.04 ? 425 ASN A C 1 ATOM 2978 O O . ASN A 1 427 ? 11.361 22.277 -4.006 1.00 47.97 ? 425 ASN A O 1 ATOM 2979 C CB . ASN A 1 427 ? 8.803 22.613 -2.904 1.00 41.22 ? 425 ASN A CB 1 ATOM 2980 C CG . ASN A 1 427 ? 7.764 23.370 -2.150 1.00 55.96 ? 425 ASN A CG 1 ATOM 2981 O OD1 . ASN A 1 427 ? 7.946 24.544 -1.802 1.00 59.00 ? 425 ASN A OD1 1 ATOM 2982 N ND2 . ASN A 1 427 ? 6.626 22.733 -1.949 1.00 40.11 ? 425 ASN A ND2 1 ATOM 2983 N N . VAL A 1 428 ? 10.523 22.521 -6.114 1.00 45.67 ? 426 VAL A N 1 ATOM 2984 C CA . VAL A 1 428 ? 11.673 21.952 -6.797 1.00 44.89 ? 426 VAL A CA 1 ATOM 2985 C C . VAL A 1 428 ? 12.842 22.952 -6.679 1.00 50.15 ? 426 VAL A C 1 ATOM 2986 O O . VAL A 1 428 ? 12.645 24.169 -6.743 1.00 47.27 ? 426 VAL A O 1 ATOM 2987 C CB . VAL A 1 428 ? 11.405 21.532 -8.280 1.00 48.16 ? 426 VAL A CB 1 ATOM 2988 C CG1 . VAL A 1 428 ? 10.252 20.564 -8.394 1.00 48.03 ? 426 VAL A CG1 1 ATOM 2989 C CG2 . VAL A 1 428 ? 11.188 22.731 -9.202 1.00 47.84 ? 426 VAL A CG2 1 ATOM 2990 N N . LYS A 1 429 ? 14.048 22.412 -6.477 1.00 50.52 ? 427 LYS A N 1 ATOM 2991 C CA . LYS A 1 429 ? 15.325 23.123 -6.405 1.00 51.22 ? 427 LYS A CA 1 ATOM 2992 C C . LYS A 1 429 ? 16.368 22.082 -6.762 1.00 58.23 ? 427 LYS A C 1 ATOM 2993 O O . LYS A 1 429 ? 16.484 21.063 -6.058 1.00 59.72 ? 427 LYS A O 1 ATOM 2994 C CB . LYS A 1 429 ? 15.568 23.736 -5.025 1.00 52.83 ? 427 LYS A CB 1 ATOM 2995 C CG . LYS A 1 429 ? 16.216 25.123 -5.107 1.00 69.98 ? 427 LYS A CG 1 ATOM 2996 C CD . LYS A 1 429 ? 16.442 25.758 -3.721 1.00 81.15 ? 427 LYS A CD 1 ATOM 2997 C CE . LYS A 1 429 ? 17.874 26.215 -3.510 1.00 96.83 ? 427 LYS A CE 1 ATOM 2998 N NZ . LYS A 1 429 ? 18.036 27.095 -2.314 1.00 106.90 ? 427 LYS A NZ 1 ATOM 2999 N N . PHE A 1 430 ? 17.041 22.267 -7.924 1.00 53.31 ? 428 PHE A N 1 ATOM 3000 C CA . PHE A 1 430 ? 18.038 21.319 -8.437 1.00 52.33 ? 428 PHE A CA 1 ATOM 3001 C C . PHE A 1 430 ? 18.952 21.990 -9.452 1.00 57.84 ? 428 PHE A C 1 ATOM 3002 O O . PHE A 1 430 ? 18.522 22.929 -10.137 1.00 57.97 ? 428 PHE A O 1 ATOM 3003 C CB . PHE A 1 430 ? 17.330 20.112 -9.077 1.00 53.93 ? 428 PHE A CB 1 ATOM 3004 C CG . PHE A 1 430 ? 16.371 20.423 -10.210 1.00 55.70 ? 428 PHE A CG 1 ATOM 3005 C CD1 . PHE A 1 430 ? 15.080 20.885 -9.950 1.00 58.32 ? 428 PHE A CD1 1 ATOM 3006 C CD2 . PHE A 1 430 ? 16.750 20.234 -11.537 1.00 58.20 ? 428 PHE A CD2 1 ATOM 3007 C CE1 . PHE A 1 430 ? 14.196 21.171 -11.000 1.00 59.07 ? 428 PHE A CE1 1 ATOM 3008 C CE2 . PHE A 1 430 ? 15.866 20.532 -12.588 1.00 60.70 ? 428 PHE A CE2 1 ATOM 3009 C CZ . PHE A 1 430 ? 14.593 20.983 -12.310 1.00 58.36 ? 428 PHE A CZ 1 ATOM 3010 N N . ASP A 1 431 ? 20.211 21.508 -9.564 1.00 54.92 ? 429 ASP A N 1 ATOM 3011 C CA . ASP A 1 431 ? 21.181 22.040 -10.536 1.00 55.42 ? 429 ASP A CA 1 ATOM 3012 C C . ASP A 1 431 ? 20.605 21.913 -11.954 1.00 58.96 ? 429 ASP A C 1 ATOM 3013 O O . ASP A 1 431 ? 20.117 20.831 -12.315 1.00 57.34 ? 429 ASP A O 1 ATOM 3014 C CB . ASP A 1 431 ? 22.510 21.263 -10.480 1.00 57.36 ? 429 ASP A CB 1 ATOM 3015 C CG . ASP A 1 431 ? 23.280 21.300 -9.177 1.00 69.51 ? 429 ASP A CG 1 ATOM 3016 O OD1 . ASP A 1 431 ? 23.010 22.206 -8.343 1.00 70.02 ? 429 ASP A OD1 1 ATOM 3017 O OD2 . ASP A 1 431 ? 24.182 20.443 -9.000 1.00 74.72 ? 429 ASP A OD2 1 ATOM 3018 N N . ALA A 1 432 ? 20.650 23.017 -12.744 1.00 55.78 ? 430 ALA A N 1 ATOM 3019 C CA . ALA A 1 432 ? 20.125 23.032 -14.116 1.00 55.26 ? 430 ALA A CA 1 ATOM 3020 C C . ALA A 1 432 ? 20.788 21.948 -14.970 1.00 61.27 ? 430 ALA A C 1 ATOM 3021 O O . ALA A 1 432 ? 21.998 21.767 -14.872 1.00 61.62 ? 430 ALA A O 1 ATOM 3022 C CB . ALA A 1 432 ? 20.303 24.396 -14.748 1.00 55.33 ? 430 ALA A CB 1 ATOM 3023 N N . PRO A 1 433 ? 20.029 21.145 -15.740 1.00 58.76 ? 431 PRO A N 1 ATOM 3024 C CA . PRO A 1 433 ? 20.681 20.094 -16.531 1.00 58.80 ? 431 PRO A CA 1 ATOM 3025 C C . PRO A 1 433 ? 21.448 20.655 -17.726 1.00 62.25 ? 431 PRO A C 1 ATOM 3026 O O . PRO A 1 433 ? 20.999 21.619 -18.367 1.00 61.23 ? 431 PRO A O 1 ATOM 3027 C CB . PRO A 1 433 ? 19.520 19.176 -16.931 1.00 60.53 ? 431 PRO A CB 1 ATOM 3028 C CG . PRO A 1 433 ? 18.346 20.084 -16.989 1.00 65.17 ? 431 PRO A CG 1 ATOM 3029 C CD . PRO A 1 433 ? 18.573 21.191 -15.993 1.00 60.72 ? 431 PRO A CD 1 ATOM 3030 N N . PHE A 1 434 ? 22.625 20.046 -17.999 1.00 59.39 ? 432 PHE A N 1 ATOM 3031 C CA . PHE A 1 434 ? 23.569 20.353 -19.094 1.00 59.53 ? 432 PHE A CA 1 ATOM 3032 C C . PHE A 1 434 ? 24.045 21.807 -19.051 1.00 67.27 ? 432 PHE A C 1 ATOM 3033 O O . PHE A 1 434 ? 24.300 22.428 -20.089 1.00 68.54 ? 432 PHE A O 1 ATOM 3034 C CB . PHE A 1 434 ? 22.991 19.951 -20.469 1.00 60.73 ? 432 PHE A CB 1 ATOM 3035 C CG . PHE A 1 434 ? 22.262 18.627 -20.416 1.00 62.22 ? 432 PHE A CG 1 ATOM 3036 C CD1 . PHE A 1 434 ? 22.966 17.426 -20.371 1.00 64.42 ? 432 PHE A CD1 1 ATOM 3037 C CD2 . PHE A 1 434 ? 20.873 18.582 -20.327 1.00 64.06 ? 432 PHE A CD2 1 ATOM 3038 C CE1 . PHE A 1 434 ? 22.294 16.208 -20.240 1.00 65.09 ? 432 PHE A CE1 1 ATOM 3039 C CE2 . PHE A 1 434 ? 20.203 17.362 -20.202 1.00 66.51 ? 432 PHE A CE2 1 ATOM 3040 C CZ . PHE A 1 434 ? 20.917 16.185 -20.164 1.00 64.26 ? 432 PHE A CZ 1 ATOM 3041 N N . ARG A 1 435 ? 24.168 22.345 -17.830 1.00 65.12 ? 433 ARG A N 1 ATOM 3042 C CA . ARG A 1 435 ? 24.621 23.708 -17.607 1.00 65.83 ? 433 ARG A CA 1 ATOM 3043 C C . ARG A 1 435 ? 26.119 23.774 -17.938 1.00 74.58 ? 433 ARG A C 1 ATOM 3044 O O . ARG A 1 435 ? 26.796 22.740 -17.785 1.00 74.38 ? 433 ARG A O 1 ATOM 3045 C CB . ARG A 1 435 ? 24.303 24.171 -16.162 1.00 63.00 ? 433 ARG A CB 1 ATOM 3046 C CG . ARG A 1 435 ? 25.039 23.453 -15.035 1.00 68.19 ? 433 ARG A CG 1 ATOM 3047 C CD . ARG A 1 435 ? 24.452 23.837 -13.690 1.00 82.74 ? 433 ARG A CD 1 ATOM 3048 N NE . ARG A 1 435 ? 25.452 23.980 -12.628 1.00 96.72 ? 433 ARG A NE 1 ATOM 3049 C CZ . ARG A 1 435 ? 25.901 22.987 -11.862 1.00 117.63 ? 433 ARG A CZ 1 ATOM 3050 N NH1 . ARG A 1 435 ? 26.797 23.227 -10.913 1.00 112.46 ? 433 ARG A NH1 1 ATOM 3051 N NH2 . ARG A 1 435 ? 25.472 21.744 -12.050 1.00 101.55 ? 433 ARG A NH2 1 ATOM 3052 N N . PRO A 1 436 ? 26.656 24.923 -18.451 1.00 73.80 ? 434 PRO A N 1 ATOM 3053 C CA . PRO A 1 436 ? 28.108 24.985 -18.732 1.00 74.37 ? 434 PRO A CA 1 ATOM 3054 C C . PRO A 1 436 ? 28.893 24.574 -17.483 1.00 81.16 ? 434 PRO A C 1 ATOM 3055 O O . PRO A 1 436 ? 28.543 25.005 -16.373 1.00 80.35 ? 434 PRO A O 1 ATOM 3056 C CB . PRO A 1 436 ? 28.338 26.456 -19.105 1.00 75.64 ? 434 PRO A CB 1 ATOM 3057 C CG . PRO A 1 436 ? 27.012 26.952 -19.539 1.00 79.48 ? 434 PRO A CG 1 ATOM 3058 C CD . PRO A 1 436 ? 26.009 26.229 -18.706 1.00 74.99 ? 434 PRO A CD 1 ATOM 3059 N N . ALA A 1 437 ? 29.886 23.665 -17.654 1.00 80.26 ? 435 ALA A N 1 ATOM 3060 C CA . ALA A 1 437 ? 30.728 23.074 -16.586 1.00 80.85 ? 435 ALA A CA 1 ATOM 3061 C C . ALA A 1 437 ? 31.098 24.037 -15.441 1.00 85.41 ? 435 ALA A C 1 ATOM 3062 O O . ALA A 1 437 ? 31.138 23.616 -14.281 1.00 85.05 ? 435 ALA A O 1 ATOM 3063 C CB . ALA A 1 437 ? 31.985 22.454 -17.187 1.00 81.55 ? 435 ALA A CB 1 ATOM 3064 N N . ASP A 1 438 ? 31.311 25.337 -15.772 1.00 82.21 ? 436 ASP A N 1 ATOM 3065 C CA . ASP A 1 438 ? 31.653 26.401 -14.830 1.00 81.94 ? 436 ASP A CA 1 ATOM 3066 C C . ASP A 1 438 ? 30.470 26.830 -13.946 1.00 86.99 ? 436 ASP A C 1 ATOM 3067 O O . ASP A 1 438 ? 30.603 26.830 -12.720 1.00 85.87 ? 436 ASP A O 1 ATOM 3068 C CB . ASP A 1 438 ? 32.233 27.612 -15.579 1.00 83.23 ? 436 ASP A CB 1 ATOM 3069 N N . THR A 1 439 ? 29.316 27.177 -14.582 1.00 85.03 ? 437 THR A N 1 ATOM 3070 C CA . THR A 1 439 ? 28.078 27.722 -13.985 1.00 84.87 ? 437 THR A CA 1 ATOM 3071 C C . THR A 1 439 ? 27.477 26.935 -12.807 1.00 86.93 ? 437 THR A C 1 ATOM 3072 O O . THR A 1 439 ? 27.658 25.719 -12.706 1.00 86.25 ? 437 THR A O 1 ATOM 3073 C CB . THR A 1 439 ? 26.991 27.927 -15.051 1.00 96.57 ? 437 THR A CB 1 ATOM 3074 O OG1 . THR A 1 439 ? 26.586 26.660 -15.563 1.00 99.42 ? 437 THR A OG1 1 ATOM 3075 C CG2 . THR A 1 439 ? 27.404 28.898 -16.175 1.00 94.09 ? 437 THR A CG2 1 ATOM 3076 N N . HIS A 1 440 ? 26.726 27.657 -11.945 1.00 82.55 ? 438 HIS A N 1 ATOM 3077 C CA . HIS A 1 440 ? 26.039 27.120 -10.772 1.00 82.38 ? 438 HIS A CA 1 ATOM 3078 C C . HIS A 1 440 ? 24.493 27.370 -10.783 1.00 85.82 ? 438 HIS A C 1 ATOM 3079 O O . HIS A 1 440 ? 23.856 27.298 -9.720 1.00 85.68 ? 438 HIS A O 1 ATOM 3080 C CB . HIS A 1 440 ? 26.693 27.658 -9.487 1.00 83.15 ? 438 HIS A CB 1 ATOM 3081 N N . ASN A 1 441 ? 23.898 27.614 -11.993 1.00 80.56 ? 439 ASN A N 1 ATOM 3082 C CA . ASN A 1 441 ? 22.456 27.870 -12.214 1.00 79.23 ? 439 ASN A CA 1 ATOM 3083 C C . ASN A 1 441 ? 21.545 26.773 -11.656 1.00 77.26 ? 439 ASN A C 1 ATOM 3084 O O . ASN A 1 441 ? 21.835 25.583 -11.804 1.00 77.34 ? 439 ASN A O 1 ATOM 3085 C CB . ASN A 1 441 ? 22.129 28.040 -13.711 1.00 83.09 ? 439 ASN A CB 1 ATOM 3086 C CG . ASN A 1 441 ? 23.039 28.958 -14.486 1.00 117.48 ? 439 ASN A CG 1 ATOM 3087 O OD1 . ASN A 1 441 ? 23.781 28.510 -15.366 1.00 111.48 ? 439 ASN A OD1 1 ATOM 3088 N ND2 . ASN A 1 441 ? 22.964 30.263 -14.221 1.00 112.80 ? 439 ASN A ND2 1 ATOM 3089 N N . GLU A 1 442 ? 20.431 27.172 -11.051 1.00 68.52 ? 440 GLU A N 1 ATOM 3090 C CA . GLU A 1 442 ? 19.489 26.197 -10.527 1.00 66.53 ? 440 GLU A CA 1 ATOM 3091 C C . GLU A 1 442 ? 18.053 26.497 -10.946 1.00 63.69 ? 440 GLU A C 1 ATOM 3092 O O . GLU A 1 442 ? 17.679 27.660 -11.096 1.00 61.76 ? 440 GLU A O 1 ATOM 3093 C CB . GLU A 1 442 ? 19.628 26.005 -9.006 1.00 68.19 ? 440 GLU A CB 1 ATOM 3094 C CG . GLU A 1 442 ? 19.384 27.248 -8.168 1.00 81.48 ? 440 GLU A CG 1 ATOM 3095 C CD . GLU A 1 442 ? 19.562 27.065 -6.672 1.00 110.96 ? 440 GLU A CD 1 ATOM 3096 O OE1 . GLU A 1 442 ? 19.406 28.067 -5.935 1.00 111.67 ? 440 GLU A OE1 1 ATOM 3097 O OE2 . GLU A 1 442 ? 19.868 25.929 -6.237 1.00 103.94 ? 440 GLU A OE2 1 ATOM 3098 N N . VAL A 1 443 ? 17.270 25.427 -11.167 1.00 56.37 ? 441 VAL A N 1 ATOM 3099 C CA . VAL A 1 443 ? 15.868 25.502 -11.558 1.00 53.81 ? 441 VAL A CA 1 ATOM 3100 C C . VAL A 1 443 ? 15.001 25.507 -10.298 1.00 55.81 ? 441 VAL A C 1 ATOM 3101 O O . VAL A 1 443 ? 15.088 24.601 -9.469 1.00 56.74 ? 441 VAL A O 1 ATOM 3102 C CB . VAL A 1 443 ? 15.465 24.389 -12.560 1.00 56.26 ? 441 VAL A CB 1 ATOM 3103 C CG1 . VAL A 1 443 ? 13.998 24.535 -13.003 1.00 55.88 ? 441 VAL A CG1 1 ATOM 3104 C CG2 . VAL A 1 443 ? 16.399 24.375 -13.772 1.00 55.44 ? 441 VAL A CG2 1 ATOM 3105 N N . ARG A 1 444 ? 14.213 26.565 -10.141 1.00 50.39 ? 442 ARG A N 1 ATOM 3106 C CA . ARG A 1 444 ? 13.289 26.780 -9.030 1.00 49.66 ? 442 ARG A CA 1 ATOM 3107 C C . ARG A 1 444 ? 12.179 27.720 -9.469 1.00 49.14 ? 442 ARG A C 1 ATOM 3108 O O . ARG A 1 444 ? 12.280 28.334 -10.536 1.00 46.71 ? 442 ARG A O 1 ATOM 3109 C CB . ARG A 1 444 ? 14.018 27.308 -7.763 1.00 52.33 ? 442 ARG A CB 1 ATOM 3110 C CG . ARG A 1 444 ? 14.704 28.668 -7.906 1.00 61.78 ? 442 ARG A CG 1 ATOM 3111 C CD . ARG A 1 444 ? 15.713 28.949 -6.804 1.00 79.18 ? 442 ARG A CD 1 ATOM 3112 N NE . ARG A 1 444 ? 15.108 28.992 -5.468 1.00 97.14 ? 442 ARG A NE 1 ATOM 3113 C CZ . ARG A 1 444 ? 15.770 29.263 -4.343 1.00 113.64 ? 442 ARG A CZ 1 ATOM 3114 N NH1 . ARG A 1 444 ? 17.070 29.536 -4.376 1.00 102.53 ? 442 ARG A NH1 1 ATOM 3115 N NH2 . ARG A 1 444 ? 15.136 29.265 -3.178 1.00 97.75 ? 442 ARG A NH2 1 ATOM 3116 N N . PHE A 1 445 ? 11.129 27.844 -8.644 1.00 44.94 ? 443 PHE A N 1 ATOM 3117 C CA . PHE A 1 445 ? 10.027 28.765 -8.946 1.00 44.56 ? 443 PHE A CA 1 ATOM 3118 C C . PHE A 1 445 ? 9.657 29.556 -7.723 1.00 47.47 ? 443 PHE A C 1 ATOM 3119 O O . PHE A 1 445 ? 9.684 28.999 -6.632 1.00 49.69 ? 443 PHE A O 1 ATOM 3120 C CB . PHE A 1 445 ? 8.770 28.003 -9.395 1.00 46.18 ? 443 PHE A CB 1 ATOM 3121 C CG . PHE A 1 445 ? 8.953 26.986 -10.488 1.00 47.57 ? 443 PHE A CG 1 ATOM 3122 C CD1 . PHE A 1 445 ? 8.934 27.367 -11.825 1.00 49.90 ? 443 PHE A CD1 1 ATOM 3123 C CD2 . PHE A 1 445 ? 9.073 25.637 -10.190 1.00 49.19 ? 443 PHE A CD2 1 ATOM 3124 C CE1 . PHE A 1 445 ? 9.083 26.420 -12.839 1.00 49.83 ? 443 PHE A CE1 1 ATOM 3125 C CE2 . PHE A 1 445 ? 9.170 24.685 -11.217 1.00 51.16 ? 443 PHE A CE2 1 ATOM 3126 C CZ . PHE A 1 445 ? 9.202 25.088 -12.528 1.00 48.20 ? 443 PHE A CZ 1 ATOM 3127 N N . ASP A 1 446 ? 9.211 30.808 -7.891 1.00 41.36 ? 444 ASP A N 1 ATOM 3128 C CA . ASP A 1 446 ? 8.675 31.579 -6.772 1.00 40.28 ? 444 ASP A CA 1 ATOM 3129 C C . ASP A 1 446 ? 7.358 30.856 -6.336 1.00 44.87 ? 444 ASP A C 1 ATOM 3130 O O . ASP A 1 446 ? 6.895 29.960 -7.063 1.00 43.90 ? 444 ASP A O 1 ATOM 3131 C CB . ASP A 1 446 ? 8.439 33.058 -7.190 1.00 41.53 ? 444 ASP A CB 1 ATOM 3132 C CG . ASP A 1 446 ? 7.093 33.404 -7.827 1.00 47.74 ? 444 ASP A CG 1 ATOM 3133 O OD1 . ASP A 1 446 ? 6.347 32.485 -8.162 1.00 46.90 ? 444 ASP A OD1 1 ATOM 3134 O OD2 . ASP A 1 446 ? 6.819 34.609 -8.037 1.00 53.37 ? 444 ASP A OD2 1 ATOM 3135 N N . ARG A 1 447 ? 6.739 31.264 -5.198 1.00 41.55 ? 445 ARG A N 1 ATOM 3136 C CA . ARG A 1 447 ? 5.517 30.647 -4.650 1.00 41.01 ? 445 ARG A CA 1 ATOM 3137 C C . ARG A 1 447 ? 4.237 30.706 -5.601 1.00 46.14 ? 445 ARG A C 1 ATOM 3138 O O . ARG A 1 447 ? 3.163 30.206 -5.246 1.00 44.78 ? 445 ARG A O 1 ATOM 3139 C CB . ARG A 1 447 ? 5.222 31.237 -3.260 1.00 39.62 ? 445 ARG A CB 1 ATOM 3140 C CG . ARG A 1 447 ? 4.693 32.687 -3.269 1.00 58.35 ? 445 ARG A CG 1 ATOM 3141 C CD . ARG A 1 447 ? 4.679 33.378 -1.904 1.00 68.23 ? 445 ARG A CD 1 ATOM 3142 N NE . ARG A 1 447 ? 4.125 32.552 -0.830 1.00 74.18 ? 445 ARG A NE 1 ATOM 3143 C CZ . ARG A 1 447 ? 4.497 32.628 0.444 1.00 89.78 ? 445 ARG A CZ 1 ATOM 3144 N NH1 . ARG A 1 447 ? 3.944 31.832 1.350 1.00 81.81 ? 445 ARG A NH1 1 ATOM 3145 N NH2 . ARG A 1 447 ? 5.414 33.512 0.827 1.00 71.74 ? 445 ARG A NH2 1 ATOM 3146 N N . PHE A 1 448 ? 4.377 31.317 -6.784 1.00 45.13 ? 446 PHE A N 1 ATOM 3147 C CA . PHE A 1 448 ? 3.315 31.500 -7.783 1.00 46.32 ? 446 PHE A CA 1 ATOM 3148 C C . PHE A 1 448 ? 3.633 30.857 -9.146 1.00 47.23 ? 446 PHE A C 1 ATOM 3149 O O . PHE A 1 448 ? 2.865 31.002 -10.083 1.00 47.24 ? 446 PHE A O 1 ATOM 3150 C CB . PHE A 1 448 ? 2.957 32.994 -7.927 1.00 49.42 ? 446 PHE A CB 1 ATOM 3151 C CG . PHE A 1 448 ? 2.428 33.608 -6.647 1.00 52.70 ? 446 PHE A CG 1 ATOM 3152 C CD1 . PHE A 1 448 ? 1.245 33.151 -6.072 1.00 55.89 ? 446 PHE A CD1 1 ATOM 3153 C CD2 . PHE A 1 448 ? 3.129 34.618 -6.000 1.00 58.23 ? 446 PHE A CD2 1 ATOM 3154 C CE1 . PHE A 1 448 ? 0.757 33.710 -4.887 1.00 57.63 ? 446 PHE A CE1 1 ATOM 3155 C CE2 . PHE A 1 448 ? 2.632 35.192 -4.817 1.00 62.34 ? 446 PHE A CE2 1 ATOM 3156 C CZ . PHE A 1 448 ? 1.451 34.726 -4.264 1.00 59.41 ? 446 PHE A CZ 1 ATOM 3157 N N . GLY A 1 449 ? 4.728 30.111 -9.211 1.00 41.64 ? 447 GLY A N 1 ATOM 3158 C CA . GLY A 1 449 ? 5.126 29.364 -10.390 1.00 41.02 ? 447 GLY A CA 1 ATOM 3159 C C . GLY A 1 449 ? 6.089 30.051 -11.323 1.00 44.13 ? 447 GLY A C 1 ATOM 3160 O O . GLY A 1 449 ? 6.589 29.416 -12.263 1.00 43.19 ? 447 GLY A O 1 ATOM 3161 N N . ASP A 1 450 ? 6.368 31.345 -11.056 1.00 39.78 ? 448 ASP A N 1 ATOM 3162 C CA . ASP A 1 450 ? 7.241 32.157 -11.888 1.00 39.36 ? 448 ASP A CA 1 ATOM 3163 C C . ASP A 1 450 ? 8.733 31.882 -11.732 1.00 44.21 ? 448 ASP A C 1 ATOM 3164 O O . ASP A 1 450 ? 9.197 31.591 -10.621 1.00 43.63 ? 448 ASP A O 1 ATOM 3165 C CB . ASP A 1 450 ? 6.960 33.640 -11.658 1.00 40.99 ? 448 ASP A CB 1 ATOM 3166 C CG . ASP A 1 450 ? 5.525 34.076 -11.866 1.00 53.01 ? 448 ASP A CG 1 ATOM 3167 O OD1 . ASP A 1 450 ? 4.922 33.685 -12.905 1.00 52.40 ? 448 ASP A OD1 1 ATOM 3168 O OD2 . ASP A 1 450 ? 5.021 34.872 -11.034 1.00 61.40 ? 448 ASP A OD2 1 ATOM 3169 N N . GLY A 1 451 ? 9.458 32.039 -12.848 1.00 41.77 ? 449 GLY A N 1 ATOM 3170 C CA . GLY A 1 451 ? 10.917 31.964 -12.958 1.00 42.48 ? 449 GLY A CA 1 ATOM 3171 C C . GLY A 1 451 ? 11.538 33.304 -12.595 1.00 50.29 ? 449 GLY A C 1 ATOM 3172 O O . GLY A 1 451 ? 10.818 34.293 -12.394 1.00 48.45 ? 449 GLY A O 1 ATOM 3173 N N . ILE A 1 452 ? 12.845 33.385 -12.580 1.00 52.13 ? 450 ILE A N 1 ATOM 3174 C CA . ILE A 1 452 ? 13.458 34.608 -12.112 1.00 54.02 ? 450 ILE A CA 1 ATOM 3175 C C . ILE A 1 452 ? 14.089 35.489 -13.175 1.00 59.96 ? 450 ILE A C 1 ATOM 3176 O O . ILE A 1 452 ? 14.807 35.025 -14.030 1.00 60.10 ? 450 ILE A O 1 ATOM 3177 C CB . ILE A 1 452 ? 14.449 34.308 -10.998 1.00 57.91 ? 450 ILE A CB 1 ATOM 3178 C CG1 . ILE A 1 452 ? 13.694 33.752 -9.789 1.00 58.36 ? 450 ILE A CG1 1 ATOM 3179 C CG2 . ILE A 1 452 ? 15.224 35.551 -10.635 1.00 58.28 ? 450 ILE A CG2 1 ATOM 3180 C CD1 . ILE A 1 452 ? 13.762 32.247 -9.674 1.00 59.81 ? 450 ILE A CD1 1 ATOM 3181 N N . GLY A 1 453 ? 13.789 36.775 -13.083 1.00 56.23 ? 451 GLY A N 1 ATOM 3182 C CA . GLY A 1 453 ? 14.179 37.801 -14.050 1.00 55.93 ? 451 GLY A CA 1 ATOM 3183 C C . GLY A 1 453 ? 15.662 37.998 -14.319 1.00 62.01 ? 451 GLY A C 1 ATOM 3184 O O . GLY A 1 453 ? 16.282 38.858 -13.674 1.00 62.76 ? 451 GLY A O 1 ATOM 3185 N N . ARG A 1 454 ? 16.231 37.224 -15.322 1.00 56.78 ? 452 ARG A N 1 ATOM 3186 C CA . ARG A 1 454 ? 17.621 37.281 -15.832 1.00 55.06 ? 452 ARG A CA 1 ATOM 3187 C C . ARG A 1 454 ? 17.602 37.535 -17.371 1.00 57.39 ? 452 ARG A C 1 ATOM 3188 O O . ARG A 1 454 ? 17.141 36.666 -18.119 1.00 59.10 ? 452 ARG A O 1 ATOM 3189 C CB . ARG A 1 454 ? 18.364 35.980 -15.546 1.00 53.74 ? 452 ARG A CB 1 ATOM 3190 C CG . ARG A 1 454 ? 18.570 35.657 -14.076 1.00 66.83 ? 452 ARG A CG 1 ATOM 3191 C CD . ARG A 1 454 ? 19.404 34.390 -13.952 1.00 79.21 ? 452 ARG A CD 1 ATOM 3192 N NE . ARG A 1 454 ? 19.681 34.037 -12.560 1.00 94.93 ? 452 ARG A NE 1 ATOM 3193 C CZ . ARG A 1 454 ? 19.002 33.132 -11.857 1.00 112.03 ? 452 ARG A CZ 1 ATOM 3194 N NH1 . ARG A 1 454 ? 17.990 32.471 -12.410 1.00 100.08 ? 452 ARG A NH1 1 ATOM 3195 N NH2 . ARG A 1 454 ? 19.332 32.878 -10.597 1.00 96.19 ? 452 ARG A NH2 1 ATOM 3196 N N . TYR A 1 455 ? 18.085 38.715 -17.848 1.00 48.63 ? 453 TYR A N 1 ATOM 3197 C CA . TYR A 1 455 ? 18.038 39.074 -19.273 1.00 45.23 ? 453 TYR A CA 1 ATOM 3198 C C . TYR A 1 455 ? 19.375 39.501 -19.860 1.00 47.18 ? 453 TYR A C 1 ATOM 3199 O O . TYR A 1 455 ? 20.160 40.163 -19.203 1.00 45.99 ? 453 TYR A O 1 ATOM 3200 C CB . TYR A 1 455 ? 17.007 40.216 -19.531 1.00 44.74 ? 453 TYR A CB 1 ATOM 3201 C CG . TYR A 1 455 ? 15.611 39.958 -19.003 1.00 46.01 ? 453 TYR A CG 1 ATOM 3202 C CD1 . TYR A 1 455 ? 14.663 39.292 -19.773 1.00 48.79 ? 453 TYR A CD1 1 ATOM 3203 C CD2 . TYR A 1 455 ? 15.245 40.348 -17.721 1.00 46.39 ? 453 TYR A CD2 1 ATOM 3204 C CE1 . TYR A 1 455 ? 13.395 38.992 -19.267 1.00 49.49 ? 453 TYR A CE1 1 ATOM 3205 C CE2 . TYR A 1 455 ? 13.990 40.034 -17.197 1.00 47.36 ? 453 TYR A CE2 1 ATOM 3206 C CZ . TYR A 1 455 ? 13.063 39.360 -17.976 1.00 53.62 ? 453 TYR A CZ 1 ATOM 3207 O OH . TYR A 1 455 ? 11.801 39.094 -17.481 1.00 53.22 ? 453 TYR A OH 1 ATOM 3208 N N . ASN A 1 456 ? 19.583 39.189 -21.143 1.00 43.73 ? 454 ASN A N 1 ATOM 3209 C CA . ASN A 1 456 ? 20.719 39.629 -21.960 1.00 42.26 ? 454 ASN A CA 1 ATOM 3210 C C . ASN A 1 456 ? 20.232 40.793 -22.823 1.00 43.15 ? 454 ASN A C 1 ATOM 3211 O O . ASN A 1 456 ? 19.149 40.704 -23.389 1.00 43.67 ? 454 ASN A O 1 ATOM 3212 C CB . ASN A 1 456 ? 21.248 38.488 -22.848 1.00 37.60 ? 454 ASN A CB 1 ATOM 3213 C CG . ASN A 1 456 ? 22.027 37.442 -22.081 1.00 60.54 ? 454 ASN A CG 1 ATOM 3214 O OD1 . ASN A 1 456 ? 22.760 37.735 -21.125 1.00 55.28 ? 454 ASN A OD1 1 ATOM 3215 N ND2 . ASN A 1 456 ? 21.871 36.186 -22.469 1.00 55.48 ? 454 ASN A ND2 1 ATOM 3216 N N . ILE A 1 457 ? 21.002 41.888 -22.877 1.00 36.77 ? 455 ILE A N 1 ATOM 3217 C CA . ILE A 1 457 ? 20.719 43.093 -23.669 1.00 35.97 ? 455 ILE A CA 1 ATOM 3218 C C . ILE A 1 457 ? 21.694 43.088 -24.877 1.00 42.91 ? 455 ILE A C 1 ATOM 3219 O O . ILE A 1 457 ? 22.905 42.873 -24.717 1.00 42.92 ? 455 ILE A O 1 ATOM 3220 C CB . ILE A 1 457 ? 20.868 44.389 -22.790 1.00 37.64 ? 455 ILE A CB 1 ATOM 3221 C CG1 . ILE A 1 457 ? 19.886 44.359 -21.581 1.00 38.67 ? 455 ILE A CG1 1 ATOM 3222 C CG2 . ILE A 1 457 ? 20.715 45.682 -23.598 1.00 32.79 ? 455 ILE A CG2 1 ATOM 3223 C CD1 . ILE A 1 457 ? 20.424 44.908 -20.349 1.00 46.03 ? 455 ILE A CD1 1 ATOM 3224 N N . PHE A 1 458 ? 21.159 43.313 -26.075 1.00 39.35 ? 456 PHE A N 1 ATOM 3225 C CA . PHE A 1 458 ? 21.960 43.354 -27.280 1.00 38.59 ? 456 PHE A CA 1 ATOM 3226 C C . PHE A 1 458 ? 21.841 44.689 -27.980 1.00 44.70 ? 456 PHE A C 1 ATOM 3227 O O . PHE A 1 458 ? 20.873 45.422 -27.766 1.00 45.28 ? 456 PHE A O 1 ATOM 3228 C CB . PHE A 1 458 ? 21.487 42.281 -28.240 1.00 40.02 ? 456 PHE A CB 1 ATOM 3229 C CG . PHE A 1 458 ? 21.660 40.871 -27.761 1.00 41.89 ? 456 PHE A CG 1 ATOM 3230 C CD1 . PHE A 1 458 ? 20.755 40.308 -26.866 1.00 44.18 ? 456 PHE A CD1 1 ATOM 3231 C CD2 . PHE A 1 458 ? 22.690 40.077 -28.252 1.00 44.52 ? 456 PHE A CD2 1 ATOM 3232 C CE1 . PHE A 1 458 ? 20.897 38.987 -26.450 1.00 45.38 ? 456 PHE A CE1 1 ATOM 3233 C CE2 . PHE A 1 458 ? 22.831 38.752 -27.833 1.00 47.37 ? 456 PHE A CE2 1 ATOM 3234 C CZ . PHE A 1 458 ? 21.933 38.216 -26.934 1.00 45.06 ? 456 PHE A CZ 1 ATOM 3235 N N . THR A 1 459 ? 22.821 44.987 -28.853 1.00 41.99 ? 457 THR A N 1 ATOM 3236 C CA . THR A 1 459 ? 22.773 46.106 -29.790 1.00 41.14 ? 457 THR A CA 1 ATOM 3237 C C . THR A 1 459 ? 22.940 45.505 -31.155 1.00 43.65 ? 457 THR A C 1 ATOM 3238 O O . THR A 1 459 ? 23.668 44.502 -31.291 1.00 42.11 ? 457 THR A O 1 ATOM 3239 C CB . THR A 1 459 ? 23.687 47.292 -29.448 1.00 49.57 ? 457 THR A CB 1 ATOM 3240 O OG1 . THR A 1 459 ? 23.141 48.466 -30.058 1.00 46.11 ? 457 THR A OG1 1 ATOM 3241 C CG2 . THR A 1 459 ? 25.143 47.092 -29.897 1.00 49.22 ? 457 THR A CG2 1 ATOM 3242 N N . TYR A 1 460 ? 22.179 46.024 -32.138 1.00 40.77 ? 458 TYR A N 1 ATOM 3243 C CA . TYR A 1 460 ? 22.274 45.569 -33.532 1.00 40.89 ? 458 TYR A CA 1 ATOM 3244 C C . TYR A 1 460 ? 23.194 46.564 -34.230 1.00 48.47 ? 458 TYR A C 1 ATOM 3245 O O . TYR A 1 460 ? 22.892 47.772 -34.281 1.00 48.35 ? 458 TYR A O 1 ATOM 3246 C CB . TYR A 1 460 ? 20.908 45.536 -34.204 1.00 41.47 ? 458 TYR A CB 1 ATOM 3247 C CG . TYR A 1 460 ? 20.932 44.915 -35.577 1.00 41.55 ? 458 TYR A CG 1 ATOM 3248 C CD1 . TYR A 1 460 ? 21.144 43.548 -35.741 1.00 42.71 ? 458 TYR A CD1 1 ATOM 3249 C CD2 . TYR A 1 460 ? 20.661 45.673 -36.707 1.00 42.10 ? 458 TYR A CD2 1 ATOM 3250 C CE1 . TYR A 1 460 ? 21.137 42.965 -36.999 1.00 40.45 ? 458 TYR A CE1 1 ATOM 3251 C CE2 . TYR A 1 460 ? 20.644 45.097 -37.974 1.00 42.92 ? 458 TYR A CE2 1 ATOM 3252 C CZ . TYR A 1 460 ? 20.889 43.742 -38.113 1.00 47.66 ? 458 TYR A CZ 1 ATOM 3253 O OH . TYR A 1 460 ? 20.874 43.164 -39.356 1.00 53.56 ? 458 TYR A OH 1 ATOM 3254 N N . LEU A 1 461 ? 24.380 46.081 -34.635 1.00 46.52 ? 459 LEU A N 1 ATOM 3255 C CA . LEU A 1 461 ? 25.391 46.933 -35.251 1.00 47.08 ? 459 LEU A CA 1 ATOM 3256 C C . LEU A 1 461 ? 25.871 46.438 -36.575 1.00 51.32 ? 459 LEU A C 1 ATOM 3257 O O . LEU A 1 461 ? 25.722 45.259 -36.904 1.00 49.28 ? 459 LEU A O 1 ATOM 3258 C CB . LEU A 1 461 ? 26.601 47.176 -34.301 1.00 47.69 ? 459 LEU A CB 1 ATOM 3259 C CG . LEU A 1 461 ? 27.301 45.954 -33.634 1.00 53.16 ? 459 LEU A CG 1 ATOM 3260 C CD1 . LEU A 1 461 ? 28.312 45.219 -34.607 1.00 53.34 ? 459 LEU A CD1 1 ATOM 3261 C CD2 . LEU A 1 461 ? 28.001 46.367 -32.357 1.00 54.49 ? 459 LEU A CD2 1 ATOM 3262 N N . ARG A 1 462 ? 26.514 47.338 -37.309 1.00 52.14 ? 460 ARG A N 1 ATOM 3263 C CA . ARG A 1 462 ? 27.181 47.015 -38.550 1.00 54.16 ? 460 ARG A CA 1 ATOM 3264 C C . ARG A 1 462 ? 28.659 46.797 -38.191 1.00 64.91 ? 460 ARG A C 1 ATOM 3265 O O . ARG A 1 462 ? 29.340 47.741 -37.777 1.00 65.16 ? 460 ARG A O 1 ATOM 3266 C CB . ARG A 1 462 ? 27.015 48.135 -39.568 1.00 53.91 ? 460 ARG A CB 1 ATOM 3267 C CG . ARG A 1 462 ? 27.104 47.591 -40.971 1.00 58.97 ? 460 ARG A CG 1 ATOM 3268 C CD . ARG A 1 462 ? 27.158 48.676 -42.007 1.00 67.08 ? 460 ARG A CD 1 ATOM 3269 N NE . ARG A 1 462 ? 27.360 48.069 -43.318 1.00 79.08 ? 460 ARG A NE 1 ATOM 3270 C CZ . ARG A 1 462 ? 27.655 48.739 -44.423 1.00 93.85 ? 460 ARG A CZ 1 ATOM 3271 N NH1 . ARG A 1 462 ? 27.794 50.061 -44.391 1.00 78.12 ? 460 ARG A NH1 1 ATOM 3272 N NH2 . ARG A 1 462 ? 27.819 48.093 -45.570 1.00 77.76 ? 460 ARG A NH2 1 ATOM 3273 N N . ALA A 1 463 ? 29.114 45.527 -38.275 1.00 66.50 ? 461 ALA A N 1 ATOM 3274 C CA . ALA A 1 463 ? 30.478 45.070 -37.982 1.00 68.44 ? 461 ALA A CA 1 ATOM 3275 C C . ALA A 1 463 ? 31.528 45.651 -38.967 1.00 76.81 ? 461 ALA A C 1 ATOM 3276 O O . ALA A 1 463 ? 31.165 46.143 -40.049 1.00 76.36 ? 461 ALA A O 1 ATOM 3277 C CB . ALA A 1 463 ? 30.527 43.539 -37.994 1.00 69.11 ? 461 ALA A CB 1 ATOM 3278 N N . GLY A 1 464 ? 32.810 45.582 -38.571 1.00 75.71 ? 462 GLY A N 1 ATOM 3279 C CA . GLY A 1 464 ? 33.943 46.051 -39.371 1.00 76.49 ? 462 GLY A CA 1 ATOM 3280 C C . GLY A 1 464 ? 33.964 45.460 -40.770 1.00 80.99 ? 462 GLY A C 1 ATOM 3281 O O . GLY A 1 464 ? 34.119 46.185 -41.764 1.00 79.94 ? 462 GLY A O 1 ATOM 3282 N N . SER A 1 465 ? 33.695 44.144 -40.845 1.00 78.16 ? 463 SER A N 1 ATOM 3283 C CA . SER A 1 465 ? 33.598 43.340 -42.065 1.00 78.58 ? 463 SER A CA 1 ATOM 3284 C C . SER A 1 465 ? 32.394 43.706 -43.006 1.00 83.05 ? 463 SER A C 1 ATOM 3285 O O . SER A 1 465 ? 32.128 42.972 -43.971 1.00 83.42 ? 463 SER A O 1 ATOM 3286 C CB . SER A 1 465 ? 33.579 41.853 -41.705 1.00 82.99 ? 463 SER A CB 1 ATOM 3287 O OG . SER A 1 465 ? 32.607 41.568 -40.712 1.00 92.91 ? 463 SER A OG 1 ATOM 3288 N N . GLY A 1 466 ? 31.711 44.830 -42.729 1.00 78.34 ? 464 GLY A N 1 ATOM 3289 C CA . GLY A 1 466 ? 30.567 45.322 -43.497 1.00 77.29 ? 464 GLY A CA 1 ATOM 3290 C C . GLY A 1 466 ? 29.217 44.734 -43.098 1.00 78.94 ? 464 GLY A C 1 ATOM 3291 O O . GLY A 1 466 ? 28.207 45.444 -43.110 1.00 78.29 ? 464 GLY A O 1 ATOM 3292 N N . ARG A 1 467 ? 29.186 43.420 -42.765 1.00 72.49 ? 465 ARG A N 1 ATOM 3293 C CA . ARG A 1 467 ? 27.981 42.685 -42.371 1.00 70.75 ? 465 ARG A CA 1 ATOM 3294 C C . ARG A 1 467 ? 27.366 43.168 -41.044 1.00 70.67 ? 465 ARG A C 1 ATOM 3295 O O . ARG A 1 467 ? 28.071 43.650 -40.150 1.00 70.60 ? 465 ARG A O 1 ATOM 3296 C CB . ARG A 1 467 ? 28.213 41.162 -42.353 1.00 71.03 ? 465 ARG A CB 1 ATOM 3297 C CG . ARG A 1 467 ? 29.213 40.678 -41.314 1.00 86.28 ? 465 ARG A CG 1 ATOM 3298 C CD . ARG A 1 467 ? 29.418 39.179 -41.396 1.00 104.43 ? 465 ARG A CD 1 ATOM 3299 N NE . ARG A 1 467 ? 30.363 38.704 -40.381 1.00 115.44 ? 465 ARG A NE 1 ATOM 3300 C CZ . ARG A 1 467 ? 30.022 38.344 -39.147 1.00 124.82 ? 465 ARG A CZ 1 ATOM 3301 N NH1 . ARG A 1 467 ? 28.756 38.412 -38.753 1.00 111.77 ? 465 ARG A NH1 1 ATOM 3302 N NH2 . ARG A 1 467 ? 30.947 37.925 -38.291 1.00 105.93 ? 465 ARG A NH2 1 ATOM 3303 N N . TYR A 1 468 ? 26.034 43.039 -40.936 1.00 62.89 ? 466 TYR A N 1 ATOM 3304 C CA . TYR A 1 468 ? 25.250 43.450 -39.767 1.00 59.61 ? 466 TYR A CA 1 ATOM 3305 C C . TYR A 1 468 ? 25.126 42.298 -38.780 1.00 61.03 ? 466 TYR A C 1 ATOM 3306 O O . TYR A 1 468 ? 24.927 41.147 -39.203 1.00 60.73 ? 466 TYR A O 1 ATOM 3307 C CB . TYR A 1 468 ? 23.852 43.900 -40.207 1.00 57.96 ? 466 TYR A CB 1 ATOM 3308 C CG . TYR A 1 468 ? 23.804 45.288 -40.795 1.00 56.10 ? 466 TYR A CG 1 ATOM 3309 C CD1 . TYR A 1 468 ? 23.943 45.492 -42.165 1.00 57.03 ? 466 TYR A CD1 1 ATOM 3310 C CD2 . TYR A 1 468 ? 23.562 46.393 -39.993 1.00 56.42 ? 466 TYR A CD2 1 ATOM 3311 C CE1 . TYR A 1 468 ? 23.875 46.771 -42.717 1.00 56.67 ? 466 TYR A CE1 1 ATOM 3312 C CE2 . TYR A 1 468 ? 23.472 47.673 -40.535 1.00 57.59 ? 466 TYR A CE2 1 ATOM 3313 C CZ . TYR A 1 468 ? 23.639 47.860 -41.896 1.00 64.75 ? 466 TYR A CZ 1 ATOM 3314 O OH . TYR A 1 468 ? 23.626 49.138 -42.404 1.00 66.79 ? 466 TYR A OH 1 ATOM 3315 N N . ARG A 1 469 ? 25.212 42.603 -37.465 1.00 54.45 ? 467 ARG A N 1 ATOM 3316 C CA . ARG A 1 469 ? 25.081 41.570 -36.439 1.00 53.36 ? 467 ARG A CA 1 ATOM 3317 C C . ARG A 1 469 ? 24.619 42.100 -35.091 1.00 54.90 ? 467 ARG A C 1 ATOM 3318 O O . ARG A 1 469 ? 24.701 43.309 -34.842 1.00 53.89 ? 467 ARG A O 1 ATOM 3319 C CB . ARG A 1 469 ? 26.399 40.767 -36.283 1.00 53.25 ? 467 ARG A CB 1 ATOM 3320 C CG . ARG A 1 469 ? 27.468 41.481 -35.460 1.00 60.87 ? 467 ARG A CG 1 ATOM 3321 C CD . ARG A 1 469 ? 28.742 40.679 -35.347 1.00 76.84 ? 467 ARG A CD 1 ATOM 3322 N NE . ARG A 1 469 ? 29.826 41.538 -34.881 1.00 93.08 ? 467 ARG A NE 1 ATOM 3323 C CZ . ARG A 1 469 ? 30.116 41.751 -33.602 1.00 109.55 ? 467 ARG A CZ 1 ATOM 3324 N NH1 . ARG A 1 469 ? 31.099 42.576 -33.270 1.00 96.51 ? 467 ARG A NH1 1 ATOM 3325 N NH2 . ARG A 1 469 ? 29.429 41.134 -32.645 1.00 94.87 ? 467 ARG A NH2 1 ATOM 3326 N N . TYR A 1 470 ? 24.168 41.169 -34.211 1.00 50.44 ? 468 TYR A N 1 ATOM 3327 C CA . TYR A 1 470 ? 23.801 41.450 -32.819 1.00 50.11 ? 468 TYR A CA 1 ATOM 3328 C C . TYR A 1 470 ? 25.052 41.210 -31.954 1.00 55.58 ? 468 TYR A C 1 ATOM 3329 O O . TYR A 1 470 ? 25.842 40.308 -32.224 1.00 55.39 ? 468 TYR A O 1 ATOM 3330 C CB . TYR A 1 470 ? 22.659 40.548 -32.323 1.00 50.34 ? 468 TYR A CB 1 ATOM 3331 C CG . TYR A 1 470 ? 21.323 40.773 -32.987 1.00 51.67 ? 468 TYR A CG 1 ATOM 3332 C CD1 . TYR A 1 470 ? 20.946 40.035 -34.105 1.00 53.58 ? 468 TYR A CD1 1 ATOM 3333 C CD2 . TYR A 1 470 ? 20.392 41.657 -32.444 1.00 52.40 ? 468 TYR A CD2 1 ATOM 3334 C CE1 . TYR A 1 470 ? 19.695 40.203 -34.696 1.00 53.89 ? 468 TYR A CE1 1 ATOM 3335 C CE2 . TYR A 1 470 ? 19.129 41.823 -33.017 1.00 52.40 ? 468 TYR A CE2 1 ATOM 3336 C CZ . TYR A 1 470 ? 18.787 41.091 -34.141 1.00 53.86 ? 468 TYR A CZ 1 ATOM 3337 O OH . TYR A 1 470 ? 17.578 41.291 -34.735 1.00 45.22 ? 468 TYR A OH 1 ATOM 3338 N N . GLN A 1 471 ? 25.203 42.002 -30.905 1.00 53.81 ? 469 GLN A N 1 ATOM 3339 C CA . GLN A 1 471 ? 26.329 41.977 -29.968 1.00 53.11 ? 469 GLN A CA 1 ATOM 3340 C C . GLN A 1 471 ? 25.793 42.132 -28.543 1.00 53.61 ? 469 GLN A C 1 ATOM 3341 O O . GLN A 1 471 ? 25.044 43.086 -28.273 1.00 51.85 ? 469 GLN A O 1 ATOM 3342 C CB . GLN A 1 471 ? 27.293 43.154 -30.318 1.00 54.70 ? 469 GLN A CB 1 ATOM 3343 C CG . GLN A 1 471 ? 28.320 43.534 -29.243 1.00 64.46 ? 469 GLN A CG 1 ATOM 3344 C CD . GLN A 1 471 ? 29.388 42.480 -29.090 1.00 69.95 ? 469 GLN A CD 1 ATOM 3345 O OE1 . GLN A 1 471 ? 30.162 42.228 -30.006 1.00 49.43 ? 469 GLN A OE1 1 ATOM 3346 N NE2 . GLN A 1 471 ? 29.419 41.806 -27.941 1.00 71.86 ? 469 GLN A NE2 1 ATOM 3347 N N . LYS A 1 472 ? 26.196 41.218 -27.633 1.00 49.10 ? 470 LYS A N 1 ATOM 3348 C CA . LYS A 1 472 ? 25.799 41.284 -26.220 1.00 48.35 ? 470 LYS A CA 1 ATOM 3349 C C . LYS A 1 472 ? 26.503 42.508 -25.622 1.00 52.96 ? 470 LYS A C 1 ATOM 3350 O O . LYS A 1 472 ? 27.699 42.700 -25.859 1.00 53.76 ? 470 LYS A O 1 ATOM 3351 C CB . LYS A 1 472 ? 26.172 39.989 -25.486 1.00 49.37 ? 470 LYS A CB 1 ATOM 3352 C CG . LYS A 1 472 ? 25.736 39.947 -24.026 1.00 62.43 ? 470 LYS A CG 1 ATOM 3353 C CD . LYS A 1 472 ? 25.990 38.579 -23.373 1.00 69.71 ? 470 LYS A CD 1 ATOM 3354 C CE . LYS A 1 472 ? 25.881 38.661 -21.866 1.00 76.63 ? 470 LYS A CE 1 ATOM 3355 N NZ . LYS A 1 472 ? 25.633 37.326 -21.253 1.00 81.22 ? 470 LYS A NZ 1 ATOM 3356 N N . VAL A 1 473 ? 25.745 43.402 -24.975 1.00 48.48 ? 471 VAL A N 1 ATOM 3357 C CA . VAL A 1 473 ? 26.310 44.646 -24.390 1.00 47.39 ? 471 VAL A CA 1 ATOM 3358 C C . VAL A 1 473 ? 25.900 44.820 -22.921 1.00 51.28 ? 471 VAL A C 1 ATOM 3359 O O . VAL A 1 473 ? 26.365 45.741 -22.244 1.00 51.63 ? 471 VAL A O 1 ATOM 3360 C CB . VAL A 1 473 ? 25.933 45.917 -25.199 1.00 49.49 ? 471 VAL A CB 1 ATOM 3361 C CG1 . VAL A 1 473 ? 26.335 45.796 -26.663 1.00 49.32 ? 471 VAL A CG1 1 ATOM 3362 C CG2 . VAL A 1 473 ? 24.448 46.267 -25.051 1.00 48.51 ? 471 VAL A CG2 1 ATOM 3363 N N . GLY A 1 474 ? 24.979 43.984 -22.475 1.00 46.34 ? 472 GLY A N 1 ATOM 3364 C CA . GLY A 1 474 ? 24.413 44.121 -21.156 1.00 46.05 ? 472 GLY A CA 1 ATOM 3365 C C . GLY A 1 474 ? 23.772 42.869 -20.646 1.00 51.50 ? 472 GLY A C 1 ATOM 3366 O O . GLY A 1 474 ? 23.791 41.819 -21.293 1.00 51.02 ? 472 GLY A O 1 ATOM 3367 N N . TYR A 1 475 ? 23.234 43.012 -19.453 1.00 50.36 ? 473 TYR A N 1 ATOM 3368 C CA . TYR A 1 475 ? 22.591 42.016 -18.628 1.00 51.46 ? 473 TYR A CA 1 ATOM 3369 C C . TYR A 1 475 ? 21.669 42.775 -17.671 1.00 51.75 ? 473 TYR A C 1 ATOM 3370 O O . TYR A 1 475 ? 21.888 43.955 -17.381 1.00 50.17 ? 473 TYR A O 1 ATOM 3371 C CB . TYR A 1 475 ? 23.678 41.245 -17.824 1.00 55.93 ? 473 TYR A CB 1 ATOM 3372 C CG . TYR A 1 475 ? 23.195 39.983 -17.130 1.00 63.44 ? 473 TYR A CG 1 ATOM 3373 C CD1 . TYR A 1 475 ? 22.875 38.833 -17.861 1.00 66.94 ? 473 TYR A CD1 1 ATOM 3374 C CD2 . TYR A 1 475 ? 23.139 39.905 -15.737 1.00 65.06 ? 473 TYR A CD2 1 ATOM 3375 C CE1 . TYR A 1 475 ? 22.452 37.659 -17.224 1.00 70.10 ? 473 TYR A CE1 1 ATOM 3376 C CE2 . TYR A 1 475 ? 22.742 38.729 -15.090 1.00 66.50 ? 473 TYR A CE2 1 ATOM 3377 C CZ . TYR A 1 475 ? 22.370 37.618 -15.837 1.00 78.72 ? 473 TYR A CZ 1 ATOM 3378 O OH . TYR A 1 475 ? 21.948 36.472 -15.193 1.00 80.20 ? 473 TYR A OH 1 ATOM 3379 N N . TRP A 1 476 ? 20.604 42.116 -17.242 1.00 48.65 ? 474 TRP A N 1 ATOM 3380 C CA . TRP A 1 476 ? 19.672 42.606 -16.240 1.00 48.00 ? 474 TRP A CA 1 ATOM 3381 C C . TRP A 1 476 ? 19.268 41.434 -15.389 1.00 53.01 ? 474 TRP A C 1 ATOM 3382 O O . TRP A 1 476 ? 18.674 40.465 -15.883 1.00 50.72 ? 474 TRP A O 1 ATOM 3383 C CB . TRP A 1 476 ? 18.455 43.333 -16.810 1.00 46.60 ? 474 TRP A CB 1 ATOM 3384 C CG . TRP A 1 476 ? 17.681 44.088 -15.748 1.00 47.86 ? 474 TRP A CG 1 ATOM 3385 C CD1 . TRP A 1 476 ? 17.700 45.437 -15.521 1.00 50.63 ? 474 TRP A CD1 1 ATOM 3386 C CD2 . TRP A 1 476 ? 16.776 43.529 -14.770 1.00 47.24 ? 474 TRP A CD2 1 ATOM 3387 N NE1 . TRP A 1 476 ? 16.856 45.756 -14.478 1.00 49.59 ? 474 TRP A NE1 1 ATOM 3388 C CE2 . TRP A 1 476 ? 16.288 44.604 -13.990 1.00 50.97 ? 474 TRP A CE2 1 ATOM 3389 C CE3 . TRP A 1 476 ? 16.293 42.232 -14.513 1.00 47.92 ? 474 TRP A CE3 1 ATOM 3390 C CZ2 . TRP A 1 476 ? 15.381 44.414 -12.939 1.00 49.85 ? 474 TRP A CZ2 1 ATOM 3391 C CZ3 . TRP A 1 476 ? 15.386 42.048 -13.481 1.00 49.32 ? 474 TRP A CZ3 1 ATOM 3392 C CH2 . TRP A 1 476 ? 14.946 43.127 -12.701 1.00 49.78 ? 474 TRP A CH2 1 ATOM 3393 N N . ALA A 1 477 ? 19.673 41.511 -14.108 1.00 51.44 ? 475 ALA A N 1 ATOM 3394 C CA . ALA A 1 477 ? 19.361 40.595 -13.021 1.00 51.95 ? 475 ALA A CA 1 ATOM 3395 C C . ALA A 1 477 ? 19.330 41.451 -11.757 1.00 60.75 ? 475 ALA A C 1 ATOM 3396 O O . ALA A 1 477 ? 20.380 41.858 -11.242 1.00 62.22 ? 475 ALA A O 1 ATOM 3397 C CB . ALA A 1 477 ? 20.399 39.509 -12.913 1.00 52.29 ? 475 ALA A CB 1 ATOM 3398 N N . GLU A 1 478 ? 18.111 41.797 -11.314 1.00 58.94 ? 476 GLU A N 1 ATOM 3399 C CA . GLU A 1 478 ? 17.841 42.658 -10.157 1.00 59.88 ? 476 GLU A CA 1 ATOM 3400 C C . GLU A 1 478 ? 18.613 43.997 -10.246 1.00 64.54 ? 476 GLU A C 1 ATOM 3401 O O . GLU A 1 478 ? 19.070 44.535 -9.227 1.00 66.13 ? 476 GLU A O 1 ATOM 3402 C CB . GLU A 1 478 ? 18.062 41.917 -8.815 1.00 61.35 ? 476 GLU A CB 1 ATOM 3403 C CG . GLU A 1 478 ? 17.049 42.302 -7.738 1.00 76.67 ? 476 GLU A CG 1 ATOM 3404 C CD . GLU A 1 478 ? 15.591 42.431 -8.167 1.00 107.34 ? 476 GLU A CD 1 ATOM 3405 O OE1 . GLU A 1 478 ? 15.076 43.575 -8.191 1.00 99.99 ? 476 GLU A OE1 1 ATOM 3406 O OE2 . GLU A 1 478 ? 14.975 41.394 -8.507 1.00 102.80 ? 476 GLU A OE2 1 ATOM 3407 N N . GLY A 1 479 ? 18.727 44.511 -11.476 1.00 57.06 ? 477 GLY A N 1 ATOM 3408 C CA . GLY A 1 479 ? 19.440 45.735 -11.782 1.00 55.16 ? 477 GLY A CA 1 ATOM 3409 C C . GLY A 1 479 ? 20.168 45.649 -13.106 1.00 56.78 ? 477 GLY A C 1 ATOM 3410 O O . GLY A 1 479 ? 20.511 44.560 -13.581 1.00 55.00 ? 477 GLY A O 1 ATOM 3411 N N . LEU A 1 480 ? 20.413 46.814 -13.699 1.00 52.37 ? 478 LEU A N 1 ATOM 3412 C CA . LEU A 1 480 ? 21.037 46.945 -15.004 1.00 51.40 ? 478 LEU A CA 1 ATOM 3413 C C . LEU A 1 480 ? 22.562 47.025 -14.970 1.00 54.23 ? 478 LEU A C 1 ATOM 3414 O O . LEU A 1 480 ? 23.106 47.758 -14.168 1.00 54.06 ? 478 LEU A O 1 ATOM 3415 C CB . LEU A 1 480 ? 20.423 48.176 -15.737 1.00 50.61 ? 478 LEU A CB 1 ATOM 3416 C CG . LEU A 1 480 ? 21.077 48.626 -17.033 1.00 53.71 ? 478 LEU A CG 1 ATOM 3417 C CD1 . LEU A 1 480 ? 20.770 47.679 -18.144 1.00 53.83 ? 478 LEU A CD1 1 ATOM 3418 C CD2 . LEU A 1 480 ? 20.692 50.036 -17.378 1.00 54.48 ? 478 LEU A CD2 1 ATOM 3419 N N . THR A 1 481 ? 23.231 46.325 -15.899 1.00 50.95 ? 479 THR A N 1 ATOM 3420 C CA . THR A 1 481 ? 24.680 46.358 -16.107 1.00 51.21 ? 479 THR A CA 1 ATOM 3421 C C . THR A 1 481 ? 24.887 46.511 -17.621 1.00 55.58 ? 479 THR A C 1 ATOM 3422 O O . THR A 1 481 ? 24.359 45.706 -18.391 1.00 54.08 ? 479 THR A O 1 ATOM 3423 C CB . THR A 1 481 ? 25.353 45.084 -15.562 1.00 59.50 ? 479 THR A CB 1 ATOM 3424 O OG1 . THR A 1 481 ? 25.156 45.007 -14.148 1.00 63.63 ? 479 THR A OG1 1 ATOM 3425 C CG2 . THR A 1 481 ? 26.843 45.024 -15.881 1.00 52.15 ? 479 THR A CG2 1 ATOM 3426 N N . LEU A 1 482 ? 25.634 47.559 -18.036 1.00 52.52 ? 480 LEU A N 1 ATOM 3427 C CA . LEU A 1 482 ? 25.913 47.856 -19.441 1.00 51.79 ? 480 LEU A CA 1 ATOM 3428 C C . LEU A 1 482 ? 27.365 48.164 -19.752 1.00 54.82 ? 480 LEU A C 1 ATOM 3429 O O . LEU A 1 482 ? 28.001 48.945 -19.039 1.00 54.43 ? 480 LEU A O 1 ATOM 3430 C CB . LEU A 1 482 ? 25.055 49.048 -19.926 1.00 51.49 ? 480 LEU A CB 1 ATOM 3431 C CG . LEU A 1 482 ? 23.654 48.743 -20.439 1.00 54.04 ? 480 LEU A CG 1 ATOM 3432 C CD1 . LEU A 1 482 ? 22.875 50.037 -20.673 1.00 52.77 ? 480 LEU A CD1 1 ATOM 3433 C CD2 . LEU A 1 482 ? 23.704 47.858 -21.677 1.00 54.32 ? 480 LEU A CD2 1 ATOM 3434 N N . ASP A 1 483 ? 27.860 47.626 -20.881 1.00 50.63 ? 481 ASP A N 1 ATOM 3435 C CA . ASP A 1 483 ? 29.195 47.942 -21.390 1.00 50.05 ? 481 ASP A CA 1 ATOM 3436 C C . ASP A 1 483 ? 29.046 48.824 -22.631 1.00 54.00 ? 481 ASP A C 1 ATOM 3437 O O . ASP A 1 483 ? 28.961 48.312 -23.759 1.00 51.67 ? 481 ASP A O 1 ATOM 3438 C CB . ASP A 1 483 ? 30.017 46.672 -21.680 1.00 51.54 ? 481 ASP A CB 1 ATOM 3439 C CG . ASP A 1 483 ? 31.493 46.900 -21.974 1.00 56.66 ? 481 ASP A CG 1 ATOM 3440 O OD1 . ASP A 1 483 ? 31.950 48.092 -21.942 1.00 56.29 ? 481 ASP A OD1 1 ATOM 3441 O OD2 . ASP A 1 483 ? 32.194 45.913 -22.217 1.00 59.26 ? 481 ASP A OD2 1 ATOM 3442 N N . THR A 1 484 ? 28.983 50.159 -22.395 1.00 52.31 ? 482 THR A N 1 ATOM 3443 C CA . THR A 1 484 ? 28.822 51.213 -23.405 1.00 53.22 ? 482 THR A CA 1 ATOM 3444 C C . THR A 1 484 ? 29.930 51.230 -24.447 1.00 61.86 ? 482 THR A C 1 ATOM 3445 O O . THR A 1 484 ? 29.701 51.680 -25.572 1.00 63.22 ? 482 THR A O 1 ATOM 3446 C CB . THR A 1 484 ? 28.704 52.573 -22.739 1.00 64.28 ? 482 THR A CB 1 ATOM 3447 O OG1 . THR A 1 484 ? 29.549 52.590 -21.591 1.00 69.57 ? 482 THR A OG1 1 ATOM 3448 C CG2 . THR A 1 484 ? 27.280 52.900 -22.333 1.00 63.57 ? 482 THR A CG2 1 ATOM 3449 N N . SER A 1 485 ? 31.136 50.740 -24.079 1.00 60.27 ? 483 SER A N 1 ATOM 3450 C CA . SER A 1 485 ? 32.294 50.641 -24.966 1.00 60.06 ? 483 SER A CA 1 ATOM 3451 C C . SER A 1 485 ? 31.904 49.818 -26.163 1.00 64.51 ? 483 SER A C 1 ATOM 3452 O O . SER A 1 485 ? 32.364 50.116 -27.264 1.00 64.87 ? 483 SER A O 1 ATOM 3453 C CB . SER A 1 485 ? 33.460 49.956 -24.261 1.00 64.35 ? 483 SER A CB 1 ATOM 3454 O OG . SER A 1 485 ? 33.553 48.576 -24.598 1.00 74.30 ? 483 SER A OG 1 ATOM 3455 N N . LEU A 1 486 ? 31.062 48.768 -25.935 1.00 60.42 ? 484 LEU A N 1 ATOM 3456 C CA . LEU A 1 486 ? 30.582 47.850 -26.965 1.00 59.86 ? 484 LEU A CA 1 ATOM 3457 C C . LEU A 1 486 ? 29.450 48.422 -27.821 1.00 63.52 ? 484 LEU A C 1 ATOM 3458 O O . LEU A 1 486 ? 29.215 47.889 -28.906 1.00 64.52 ? 484 LEU A O 1 ATOM 3459 C CB . LEU A 1 486 ? 30.192 46.471 -26.386 1.00 59.86 ? 484 LEU A CB 1 ATOM 3460 C CG . LEU A 1 486 ? 31.185 45.770 -25.427 1.00 64.02 ? 484 LEU A CG 1 ATOM 3461 C CD1 . LEU A 1 486 ? 30.621 44.457 -24.937 1.00 64.04 ? 484 LEU A CD1 1 ATOM 3462 C CD2 . LEU A 1 486 ? 32.553 45.526 -26.072 1.00 64.44 ? 484 LEU A CD2 1 ATOM 3463 N N . ILE A 1 487 ? 28.770 49.506 -27.368 1.00 59.14 ? 485 ILE A N 1 ATOM 3464 C CA . ILE A 1 487 ? 27.681 50.153 -28.130 1.00 58.69 ? 485 ILE A CA 1 ATOM 3465 C C . ILE A 1 487 ? 28.270 51.276 -29.009 1.00 66.23 ? 485 ILE A C 1 ATOM 3466 O O . ILE A 1 487 ? 28.732 52.275 -28.444 1.00 66.69 ? 485 ILE A O 1 ATOM 3467 C CB . ILE A 1 487 ? 26.499 50.643 -27.245 1.00 60.38 ? 485 ILE A CB 1 ATOM 3468 C CG1 . ILE A 1 487 ? 26.013 49.535 -26.288 1.00 60.24 ? 485 ILE A CG1 1 ATOM 3469 C CG2 . ILE A 1 487 ? 25.355 51.157 -28.113 1.00 58.53 ? 485 ILE A CG2 1 ATOM 3470 C CD1 . ILE A 1 487 ? 25.672 49.991 -24.927 1.00 61.67 ? 485 ILE A CD1 1 ATOM 3471 N N . PRO A 1 488 ? 28.286 51.112 -30.373 1.00 63.71 ? 486 PRO A N 1 ATOM 3472 C CA . PRO A 1 488 ? 28.897 52.134 -31.250 1.00 63.39 ? 486 PRO A CA 1 ATOM 3473 C C . PRO A 1 488 ? 28.434 53.576 -31.033 1.00 68.70 ? 486 PRO A C 1 ATOM 3474 O O . PRO A 1 488 ? 29.284 54.463 -30.920 1.00 70.13 ? 486 PRO A O 1 ATOM 3475 C CB . PRO A 1 488 ? 28.574 51.640 -32.664 1.00 64.77 ? 486 PRO A CB 1 ATOM 3476 C CG . PRO A 1 488 ? 28.367 50.199 -32.534 1.00 69.20 ? 486 PRO A CG 1 ATOM 3477 C CD . PRO A 1 488 ? 27.797 49.960 -31.163 1.00 65.16 ? 486 PRO A CD 1 ATOM 3478 N N . TRP A 1 489 ? 27.114 53.814 -30.942 1.00 63.58 ? 487 TRP A N 1 ATOM 3479 C CA . TRP A 1 489 ? 26.574 55.162 -30.738 1.00 62.29 ? 487 TRP A CA 1 ATOM 3480 C C . TRP A 1 489 ? 26.735 55.675 -29.299 1.00 65.21 ? 487 TRP A C 1 ATOM 3481 O O . TRP A 1 489 ? 26.314 56.804 -29.002 1.00 66.33 ? 487 TRP A O 1 ATOM 3482 C CB . TRP A 1 489 ? 25.113 55.262 -31.211 1.00 60.78 ? 487 TRP A CB 1 ATOM 3483 C CG . TRP A 1 489 ? 24.193 54.208 -30.651 1.00 61.80 ? 487 TRP A CG 1 ATOM 3484 C CD1 . TRP A 1 489 ? 23.709 53.112 -31.307 1.00 64.53 ? 487 TRP A CD1 1 ATOM 3485 C CD2 . TRP A 1 489 ? 23.631 54.165 -29.327 1.00 61.71 ? 487 TRP A CD2 1 ATOM 3486 N NE1 . TRP A 1 489 ? 22.885 52.391 -30.479 1.00 64.00 ? 487 TRP A NE1 1 ATOM 3487 C CE2 . TRP A 1 489 ? 22.783 53.038 -29.272 1.00 65.72 ? 487 TRP A CE2 1 ATOM 3488 C CE3 . TRP A 1 489 ? 23.734 54.993 -28.190 1.00 62.73 ? 487 TRP A CE3 1 ATOM 3489 C CZ2 . TRP A 1 489 ? 22.075 52.694 -28.113 1.00 65.02 ? 487 TRP A CZ2 1 ATOM 3490 C CZ3 . TRP A 1 489 ? 23.046 54.642 -27.040 1.00 64.13 ? 487 TRP A CZ3 1 ATOM 3491 C CH2 . TRP A 1 489 ? 22.240 53.499 -27.002 1.00 64.96 ? 487 TRP A CH2 1 ATOM 3492 N N . ALA A 1 490 ? 27.337 54.866 -28.408 1.00 59.60 ? 488 ALA A N 1 ATOM 3493 C CA . ALA A 1 490 ? 27.562 55.268 -27.017 1.00 87.34 ? 488 ALA A CA 1 ATOM 3494 C C . ALA A 1 490 ? 28.974 55.817 -26.816 1.00 116.23 ? 488 ALA A C 1 ATOM 3495 O O . ALA A 1 490 ? 29.282 56.922 -27.260 1.00 76.42 ? 488 ALA A O 1 ATOM 3496 C CB . ALA A 1 490 ? 27.306 54.099 -26.074 1.00 88.06 ? 488 ALA A CB 1 ATOM 3497 N N . LYS B 1 25 ? -23.072 24.328 -7.129 1.00 58.71 ? 23 LYS B N 1 ATOM 3498 C CA . LYS B 1 25 ? -23.468 22.913 -7.017 1.00 59.45 ? 23 LYS B CA 1 ATOM 3499 C C . LYS B 1 25 ? -24.830 22.548 -7.665 1.00 62.44 ? 23 LYS B C 1 ATOM 3500 O O . LYS B 1 25 ? -24.944 21.436 -8.211 1.00 63.65 ? 23 LYS B O 1 ATOM 3501 C CB . LYS B 1 25 ? -23.440 22.418 -5.556 1.00 62.33 ? 23 LYS B CB 1 ATOM 3502 C CG . LYS B 1 25 ? -22.344 21.376 -5.296 1.00 82.10 ? 23 LYS B CG 1 ATOM 3503 C CD . LYS B 1 25 ? -22.185 21.055 -3.802 1.00 92.75 ? 23 LYS B CD 1 ATOM 3504 C CE . LYS B 1 25 ? -20.907 20.295 -3.510 1.00 96.44 ? 23 LYS B CE 1 ATOM 3505 N NZ . LYS B 1 25 ? -20.745 19.993 -2.062 1.00 93.49 ? 23 LYS B NZ 1 ATOM 3506 N N . LYS B 1 26 ? -25.842 23.458 -7.599 1.00 55.12 ? 24 LYS B N 1 ATOM 3507 C CA . LYS B 1 26 ? -27.203 23.234 -8.133 1.00 52.96 ? 24 LYS B CA 1 ATOM 3508 C C . LYS B 1 26 ? -27.356 23.561 -9.625 1.00 52.44 ? 24 LYS B C 1 ATOM 3509 O O . LYS B 1 26 ? -26.717 24.493 -10.123 1.00 47.37 ? 24 LYS B O 1 ATOM 3510 C CB . LYS B 1 26 ? -28.240 24.086 -7.380 1.00 54.58 ? 24 LYS B CB 1 ATOM 3511 C CG . LYS B 1 26 ? -28.543 23.676 -5.961 1.00 56.31 ? 24 LYS B CG 1 ATOM 3512 C CD . LYS B 1 26 ? -29.433 24.742 -5.322 1.00 55.33 ? 24 LYS B CD 1 ATOM 3513 C CE . LYS B 1 26 ? -29.522 24.553 -3.830 1.00 56.51 ? 24 LYS B CE 1 ATOM 3514 N NZ . LYS B 1 26 ? -30.405 25.560 -3.189 1.00 55.94 ? 24 LYS B NZ 1 ATOM 3515 N N . VAL B 1 27 ? -28.273 22.819 -10.301 1.00 50.74 ? 25 VAL B N 1 ATOM 3516 C CA . VAL B 1 27 ? -28.686 22.999 -11.701 1.00 51.26 ? 25 VAL B CA 1 ATOM 3517 C C . VAL B 1 27 ? -30.223 23.100 -11.811 1.00 50.70 ? 25 VAL B C 1 ATOM 3518 O O . VAL B 1 27 ? -30.933 22.467 -11.028 1.00 50.99 ? 25 VAL B O 1 ATOM 3519 C CB . VAL B 1 27 ? -28.080 21.970 -12.718 1.00 56.58 ? 25 VAL B CB 1 ATOM 3520 C CG1 . VAL B 1 27 ? -28.657 20.567 -12.547 1.00 56.12 ? 25 VAL B CG1 1 ATOM 3521 C CG2 . VAL B 1 27 ? -28.294 22.441 -14.150 1.00 57.06 ? 25 VAL B CG2 1 ATOM 3522 N N . LEU B 1 28 ? -30.721 23.902 -12.764 1.00 42.24 ? 26 LEU B N 1 ATOM 3523 C CA . LEU B 1 28 ? -32.151 24.021 -13.022 1.00 40.32 ? 26 LEU B CA 1 ATOM 3524 C C . LEU B 1 28 ? -32.398 23.190 -14.272 1.00 45.04 ? 26 LEU B C 1 ATOM 3525 O O . LEU B 1 28 ? -31.879 23.553 -15.332 1.00 46.50 ? 26 LEU B O 1 ATOM 3526 C CB . LEU B 1 28 ? -32.557 25.495 -13.294 1.00 38.86 ? 26 LEU B CB 1 ATOM 3527 C CG . LEU B 1 28 ? -34.062 25.846 -13.272 1.00 39.82 ? 26 LEU B CG 1 ATOM 3528 C CD1 . LEU B 1 28 ? -34.278 27.362 -13.329 1.00 37.88 ? 26 LEU B CD1 1 ATOM 3529 C CD2 . LEU B 1 28 ? -34.872 25.092 -14.354 1.00 37.44 ? 26 LEU B CD2 1 ATOM 3530 N N . THR B 1 29 ? -33.167 22.083 -14.170 1.00 39.21 ? 27 THR B N 1 ATOM 3531 C CA . THR B 1 29 ? -33.445 21.291 -15.366 1.00 38.81 ? 27 THR B CA 1 ATOM 3532 C C . THR B 1 29 ? -34.939 21.111 -15.629 1.00 42.93 ? 27 THR B C 1 ATOM 3533 O O . THR B 1 29 ? -35.724 20.877 -14.714 1.00 42.81 ? 27 THR B O 1 ATOM 3534 C CB . THR B 1 29 ? -32.709 19.965 -15.408 1.00 41.74 ? 27 THR B CB 1 ATOM 3535 O OG1 . THR B 1 29 ? -33.232 19.102 -14.419 1.00 40.71 ? 27 THR B OG1 1 ATOM 3536 C CG2 . THR B 1 29 ? -31.215 20.117 -15.292 1.00 37.18 ? 27 THR B CG2 1 ATOM 3537 N N . LEU B 1 30 ? -35.307 21.267 -16.896 1.00 39.98 ? 28 LEU B N 1 ATOM 3538 C CA . LEU B 1 30 ? -36.662 21.162 -17.431 1.00 40.68 ? 28 LEU B CA 1 ATOM 3539 C C . LEU B 1 30 ? -36.650 20.244 -18.624 1.00 46.12 ? 28 LEU B C 1 ATOM 3540 O O . LEU B 1 30 ? -35.764 20.352 -19.478 1.00 44.08 ? 28 LEU B O 1 ATOM 3541 C CB . LEU B 1 30 ? -37.224 22.529 -17.852 1.00 40.35 ? 28 LEU B CB 1 ATOM 3542 C CG . LEU B 1 30 ? -37.595 23.530 -16.769 1.00 44.83 ? 28 LEU B CG 1 ATOM 3543 C CD1 . LEU B 1 30 ? -38.506 24.569 -17.338 1.00 45.39 ? 28 LEU B CD1 1 ATOM 3544 C CD2 . LEU B 1 30 ? -38.275 22.874 -15.580 1.00 46.70 ? 28 LEU B CD2 1 ATOM 3545 N N . GLU B 1 31 ? -37.611 19.314 -18.652 1.00 46.51 ? 29 GLU B N 1 ATOM 3546 C CA . GLU B 1 31 ? -37.741 18.339 -19.729 1.00 48.10 ? 29 GLU B CA 1 ATOM 3547 C C . GLU B 1 31 ? -38.254 18.965 -21.042 1.00 48.90 ? 29 GLU B C 1 ATOM 3548 O O . GLU B 1 31 ? -38.974 19.979 -21.037 1.00 47.79 ? 29 GLU B O 1 ATOM 3549 C CB . GLU B 1 31 ? -38.582 17.121 -19.301 1.00 50.61 ? 29 GLU B CB 1 ATOM 3550 C CG . GLU B 1 31 ? -37.801 16.100 -18.480 1.00 66.84 ? 29 GLU B CG 1 ATOM 3551 C CD . GLU B 1 31 ? -38.618 14.947 -17.916 1.00 100.28 ? 29 GLU B CD 1 ATOM 3552 O OE1 . GLU B 1 31 ? -39.781 14.758 -18.346 1.00 95.80 ? 29 GLU B OE1 1 ATOM 3553 O OE2 . GLU B 1 31 ? -38.083 14.220 -17.046 1.00 95.18 ? 29 GLU B OE2 1 ATOM 3554 N N . GLY B 1 32 ? -37.811 18.358 -22.135 1.00 44.59 ? 30 GLY B N 1 ATOM 3555 C CA . GLY B 1 32 ? -38.107 18.738 -23.510 1.00 45.31 ? 30 GLY B CA 1 ATOM 3556 C C . GLY B 1 32 ? -37.388 17.849 -24.510 1.00 49.38 ? 30 GLY B C 1 ATOM 3557 O O . GLY B 1 32 ? -36.463 17.125 -24.142 1.00 49.56 ? 30 GLY B O 1 ATOM 3558 N N . ASP B 1 33 ? -37.811 17.894 -25.775 1.00 46.51 ? 31 ASP B N 1 ATOM 3559 C CA . ASP B 1 33 ? -37.231 17.107 -26.877 1.00 46.60 ? 31 ASP B CA 1 ATOM 3560 C C . ASP B 1 33 ? -35.863 17.634 -27.233 1.00 48.58 ? 31 ASP B C 1 ATOM 3561 O O . ASP B 1 33 ? -34.962 16.856 -27.567 1.00 46.56 ? 31 ASP B O 1 ATOM 3562 C CB . ASP B 1 33 ? -38.163 17.134 -28.090 1.00 48.49 ? 31 ASP B CB 1 ATOM 3563 C CG . ASP B 1 33 ? -39.514 16.556 -27.750 1.00 59.36 ? 31 ASP B CG 1 ATOM 3564 O OD1 . ASP B 1 33 ? -39.609 15.307 -27.624 1.00 60.34 ? 31 ASP B OD1 1 ATOM 3565 O OD2 . ASP B 1 33 ? -40.458 17.352 -27.511 1.00 60.94 ? 31 ASP B OD2 1 ATOM 3566 N N . LEU B 1 34 ? -35.727 18.969 -27.138 1.00 45.38 ? 32 LEU B N 1 ATOM 3567 C CA . LEU B 1 34 ? -34.497 19.734 -27.339 1.00 45.70 ? 32 LEU B CA 1 ATOM 3568 C C . LEU B 1 34 ? -34.255 20.559 -26.068 1.00 51.01 ? 32 LEU B C 1 ATOM 3569 O O . LEU B 1 34 ? -35.142 21.285 -25.608 1.00 50.08 ? 32 LEU B O 1 ATOM 3570 C CB . LEU B 1 34 ? -34.561 20.659 -28.584 1.00 45.00 ? 32 LEU B CB 1 ATOM 3571 C CG . LEU B 1 34 ? -34.563 19.982 -29.961 1.00 48.41 ? 32 LEU B CG 1 ATOM 3572 C CD1 . LEU B 1 34 ? -34.712 21.006 -31.062 1.00 48.21 ? 32 LEU B CD1 1 ATOM 3573 C CD2 . LEU B 1 34 ? -33.305 19.178 -30.195 1.00 49.11 ? 32 LEU B CD2 1 ATOM 3574 N N . VAL B 1 35 ? -33.063 20.416 -25.492 1.00 47.56 ? 33 VAL B N 1 ATOM 3575 C CA . VAL B 1 35 ? -32.691 21.141 -24.291 1.00 46.64 ? 33 VAL B CA 1 ATOM 3576 C C . VAL B 1 35 ? -31.748 22.321 -24.612 1.00 48.22 ? 33 VAL B C 1 ATOM 3577 O O . VAL B 1 35 ? -30.658 22.125 -25.183 1.00 46.72 ? 33 VAL B O 1 ATOM 3578 C CB . VAL B 1 35 ? -32.095 20.190 -23.213 1.00 49.96 ? 33 VAL B CB 1 ATOM 3579 C CG1 . VAL B 1 35 ? -31.670 20.962 -21.958 1.00 49.34 ? 33 VAL B CG1 1 ATOM 3580 C CG2 . VAL B 1 35 ? -33.075 19.079 -22.855 1.00 49.49 ? 33 VAL B CG2 1 ATOM 3581 N N . LEU B 1 36 ? -32.171 23.536 -24.210 1.00 42.56 ? 34 LEU B N 1 ATOM 3582 C CA . LEU B 1 36 ? -31.313 24.703 -24.293 1.00 41.14 ? 34 LEU B CA 1 ATOM 3583 C C . LEU B 1 36 ? -30.620 24.932 -22.932 1.00 43.27 ? 34 LEU B C 1 ATOM 3584 O O . LEU B 1 36 ? -31.263 24.988 -21.877 1.00 41.83 ? 34 LEU B O 1 ATOM 3585 C CB . LEU B 1 36 ? -32.035 26.000 -24.685 1.00 40.48 ? 34 LEU B CB 1 ATOM 3586 C CG . LEU B 1 36 ? -33.145 26.026 -25.686 1.00 44.49 ? 34 LEU B CG 1 ATOM 3587 C CD1 . LEU B 1 36 ? -33.669 27.455 -25.801 1.00 44.41 ? 34 LEU B CD1 1 ATOM 3588 C CD2 . LEU B 1 36 ? -32.699 25.537 -27.035 1.00 46.76 ? 34 LEU B CD2 1 ATOM 3589 N N . GLY B 1 37 ? -29.316 25.107 -22.986 1.00 39.50 ? 35 GLY B N 1 ATOM 3590 C CA . GLY B 1 37 ? -28.527 25.477 -21.827 1.00 38.90 ? 35 GLY B CA 1 ATOM 3591 C C . GLY B 1 37 ? -28.668 26.975 -21.592 1.00 42.83 ? 35 GLY B C 1 ATOM 3592 O O . GLY B 1 37 ? -28.891 27.759 -22.519 1.00 42.51 ? 35 GLY B O 1 ATOM 3593 N N . GLY B 1 38 ? -28.590 27.357 -20.339 1.00 39.07 ? 36 GLY B N 1 ATOM 3594 C CA . GLY B 1 38 ? -28.726 28.728 -19.886 1.00 38.16 ? 36 GLY B CA 1 ATOM 3595 C C . GLY B 1 38 ? -27.617 29.058 -18.921 1.00 40.31 ? 36 GLY B C 1 ATOM 3596 O O . GLY B 1 38 ? -27.047 28.156 -18.293 1.00 40.23 ? 36 GLY B O 1 ATOM 3597 N N . LEU B 1 39 ? -27.255 30.340 -18.851 1.00 34.30 ? 37 LEU B N 1 ATOM 3598 C CA . LEU B 1 39 ? -26.168 30.753 -17.973 1.00 33.49 ? 37 LEU B CA 1 ATOM 3599 C C . LEU B 1 39 ? -26.476 32.123 -17.405 1.00 34.61 ? 37 LEU B C 1 ATOM 3600 O O . LEU B 1 39 ? -26.735 33.058 -18.161 1.00 32.02 ? 37 LEU B O 1 ATOM 3601 C CB . LEU B 1 39 ? -24.810 30.684 -18.709 1.00 33.55 ? 37 LEU B CB 1 ATOM 3602 C CG . LEU B 1 39 ? -23.535 30.896 -17.871 1.00 38.67 ? 37 LEU B CG 1 ATOM 3603 C CD1 . LEU B 1 39 ? -23.363 29.827 -16.812 1.00 37.15 ? 37 LEU B CD1 1 ATOM 3604 C CD2 . LEU B 1 39 ? -22.303 30.908 -18.786 1.00 42.42 ? 37 LEU B CD2 1 ATOM 3605 N N . PHE B 1 40 ? -26.606 32.194 -16.072 1.00 31.72 ? 38 PHE B N 1 ATOM 3606 C CA . PHE B 1 40 ? -26.963 33.436 -15.378 1.00 32.38 ? 38 PHE B CA 1 ATOM 3607 C C . PHE B 1 40 ? -26.132 33.685 -14.118 1.00 36.97 ? 38 PHE B C 1 ATOM 3608 O O . PHE B 1 40 ? -25.701 32.714 -13.455 1.00 35.55 ? 38 PHE B O 1 ATOM 3609 C CB . PHE B 1 40 ? -28.484 33.477 -15.046 1.00 33.41 ? 38 PHE B CB 1 ATOM 3610 C CG . PHE B 1 40 ? -29.366 33.443 -16.280 1.00 33.33 ? 38 PHE B CG 1 ATOM 3611 C CD1 . PHE B 1 40 ? -29.767 32.226 -16.836 1.00 34.33 ? 38 PHE B CD1 1 ATOM 3612 C CD2 . PHE B 1 40 ? -29.804 34.624 -16.875 1.00 32.66 ? 38 PHE B CD2 1 ATOM 3613 C CE1 . PHE B 1 40 ? -30.569 32.193 -17.964 1.00 34.75 ? 38 PHE B CE1 1 ATOM 3614 C CE2 . PHE B 1 40 ? -30.611 34.593 -18.002 1.00 34.83 ? 38 PHE B CE2 1 ATOM 3615 C CZ . PHE B 1 40 ? -30.994 33.382 -18.537 1.00 34.29 ? 38 PHE B CZ 1 ATOM 3616 N N . PRO B 1 41 ? -25.930 34.984 -13.769 1.00 33.88 ? 39 PRO B N 1 ATOM 3617 C CA . PRO B 1 41 ? -25.190 35.304 -12.542 1.00 33.93 ? 39 PRO B CA 1 ATOM 3618 C C . PRO B 1 41 ? -26.155 35.293 -11.351 1.00 37.50 ? 39 PRO B C 1 ATOM 3619 O O . PRO B 1 41 ? -26.394 36.336 -10.744 1.00 37.83 ? 39 PRO B O 1 ATOM 3620 C CB . PRO B 1 41 ? -24.596 36.703 -12.837 1.00 35.19 ? 39 PRO B CB 1 ATOM 3621 C CG . PRO B 1 41 ? -25.535 37.326 -13.843 1.00 38.67 ? 39 PRO B CG 1 ATOM 3622 C CD . PRO B 1 41 ? -26.377 36.220 -14.458 1.00 35.32 ? 39 PRO B CD 1 ATOM 3623 N N . VAL B 1 42 ? -26.723 34.116 -11.040 1.00 33.26 ? 40 VAL B N 1 ATOM 3624 C CA . VAL B 1 42 ? -27.691 33.943 -9.946 1.00 33.79 ? 40 VAL B CA 1 ATOM 3625 C C . VAL B 1 42 ? -27.152 34.521 -8.612 1.00 38.99 ? 40 VAL B C 1 ATOM 3626 O O . VAL B 1 42 ? -27.884 35.237 -7.931 1.00 38.30 ? 40 VAL B O 1 ATOM 3627 C CB . VAL B 1 42 ? -28.175 32.480 -9.825 1.00 36.85 ? 40 VAL B CB 1 ATOM 3628 C CG1 . VAL B 1 42 ? -29.275 32.347 -8.783 1.00 36.84 ? 40 VAL B CG1 1 ATOM 3629 C CG2 . VAL B 1 42 ? -28.639 31.953 -11.169 1.00 36.09 ? 40 VAL B CG2 1 ATOM 3630 N N . HIS B 1 43 ? -25.849 34.264 -8.298 1.00 35.74 ? 41 HIS B N 1 ATOM 3631 C CA . HIS B 1 43 ? -25.142 34.804 -7.142 1.00 34.76 ? 41 HIS B CA 1 ATOM 3632 C C . HIS B 1 43 ? -24.092 35.814 -7.604 1.00 44.49 ? 41 HIS B C 1 ATOM 3633 O O . HIS B 1 43 ? -23.685 35.814 -8.778 1.00 46.07 ? 41 HIS B O 1 ATOM 3634 C CB . HIS B 1 43 ? -24.475 33.682 -6.364 1.00 34.58 ? 41 HIS B CB 1 ATOM 3635 C CG . HIS B 1 43 ? -25.467 32.780 -5.702 1.00 38.35 ? 41 HIS B CG 1 ATOM 3636 N ND1 . HIS B 1 43 ? -25.952 31.659 -6.334 1.00 40.24 ? 41 HIS B ND1 1 ATOM 3637 C CD2 . HIS B 1 43 ? -26.096 32.907 -4.515 1.00 40.13 ? 41 HIS B CD2 1 ATOM 3638 C CE1 . HIS B 1 43 ? -26.838 31.127 -5.518 1.00 38.93 ? 41 HIS B CE1 1 ATOM 3639 N NE2 . HIS B 1 43 ? -26.954 31.841 -4.411 1.00 39.50 ? 41 HIS B NE2 1 ATOM 3640 N N . GLN B 1 44 ? -23.656 36.691 -6.683 1.00 42.70 ? 42 GLN B N 1 ATOM 3641 C CA . GLN B 1 44 ? -22.573 37.655 -6.909 1.00 41.78 ? 42 GLN B CA 1 ATOM 3642 C C . GLN B 1 44 ? -21.267 36.895 -6.679 1.00 45.66 ? 42 GLN B C 1 ATOM 3643 O O . GLN B 1 44 ? -21.323 35.717 -6.297 1.00 43.54 ? 42 GLN B O 1 ATOM 3644 C CB . GLN B 1 44 ? -22.692 38.848 -5.944 1.00 42.52 ? 42 GLN B CB 1 ATOM 3645 C CG . GLN B 1 44 ? -24.002 39.596 -6.090 1.00 52.71 ? 42 GLN B CG 1 ATOM 3646 C CD . GLN B 1 44 ? -24.434 40.361 -4.867 1.00 66.99 ? 42 GLN B CD 1 ATOM 3647 O OE1 . GLN B 1 44 ? -23.627 40.846 -4.072 1.00 61.56 ? 42 GLN B OE1 1 ATOM 3648 N NE2 . GLN B 1 44 ? -25.735 40.530 -4.723 1.00 63.64 ? 42 GLN B NE2 1 ATOM 3649 N N . LYS B 1 45 ? -20.097 37.535 -6.924 1.00 45.96 ? 43 LYS B N 1 ATOM 3650 C CA . LYS B 1 45 ? -18.794 36.877 -6.675 1.00 47.17 ? 43 LYS B CA 1 ATOM 3651 C C . LYS B 1 45 ? -18.604 36.791 -5.163 1.00 54.74 ? 43 LYS B C 1 ATOM 3652 O O . LYS B 1 45 ? -18.911 37.755 -4.462 1.00 52.53 ? 43 LYS B O 1 ATOM 3653 C CB . LYS B 1 45 ? -17.604 37.632 -7.293 1.00 49.63 ? 43 LYS B CB 1 ATOM 3654 C CG . LYS B 1 45 ? -17.873 38.388 -8.584 1.00 73.34 ? 43 LYS B CG 1 ATOM 3655 C CD . LYS B 1 45 ? -16.579 38.998 -9.108 1.00 90.92 ? 43 LYS B CD 1 ATOM 3656 C CE . LYS B 1 45 ? -16.785 39.895 -10.304 1.00 104.04 ? 43 LYS B CE 1 ATOM 3657 N NZ . LYS B 1 45 ? -15.615 39.849 -11.226 1.00 111.74 ? 43 LYS B NZ 1 ATOM 3658 N N . GLY B 1 46 ? -18.143 35.639 -4.681 1.00 57.14 ? 44 GLY B N 1 ATOM 3659 C CA . GLY B 1 46 ? -17.900 35.399 -3.263 1.00 59.69 ? 44 GLY B CA 1 ATOM 3660 C C . GLY B 1 46 ? -16.682 36.105 -2.691 1.00 71.58 ? 44 GLY B C 1 ATOM 3661 O O . GLY B 1 46 ? -16.038 36.931 -3.359 1.00 70.24 ? 44 GLY B O 1 ATOM 3662 N N . GLY B 1 47 ? -16.367 35.767 -1.440 1.00 75.37 ? 45 GLY B N 1 ATOM 3663 C CA . GLY B 1 47 ? -15.218 36.316 -0.728 1.00 78.02 ? 45 GLY B CA 1 ATOM 3664 C C . GLY B 1 47 ? -13.899 35.778 -1.262 1.00 87.89 ? 45 GLY B C 1 ATOM 3665 O O . GLY B 1 47 ? -13.892 34.995 -2.224 1.00 88.02 ? 45 GLY B O 1 ATOM 3666 N N . PRO B 1 48 ? -12.739 36.151 -0.664 1.00 87.50 ? 46 PRO B N 1 ATOM 3667 C CA . PRO B 1 48 ? -11.465 35.572 -1.145 1.00 87.65 ? 46 PRO B CA 1 ATOM 3668 C C . PRO B 1 48 ? -11.430 34.069 -0.837 1.00 91.16 ? 46 PRO B C 1 ATOM 3669 O O . PRO B 1 48 ? -10.770 33.290 -1.534 1.00 90.67 ? 46 PRO B O 1 ATOM 3670 C CB . PRO B 1 48 ? -10.400 36.357 -0.374 1.00 89.54 ? 46 PRO B CB 1 ATOM 3671 C CG . PRO B 1 48 ? -11.093 36.815 0.875 1.00 94.31 ? 46 PRO B CG 1 ATOM 3672 C CD . PRO B 1 48 ? -12.537 37.032 0.509 1.00 89.63 ? 46 PRO B CD 1 ATOM 3673 N N . ALA B 1 49 ? -12.219 33.678 0.189 1.00 86.93 ? 47 ALA B N 1 ATOM 3674 C CA . ALA B 1 49 ? -12.401 32.331 0.694 1.00 86.33 ? 47 ALA B CA 1 ATOM 3675 C C . ALA B 1 49 ? -13.459 31.526 -0.083 1.00 88.89 ? 47 ALA B C 1 ATOM 3676 O O . ALA B 1 49 ? -13.199 30.364 -0.412 1.00 88.21 ? 47 ALA B O 1 ATOM 3677 C CB . ALA B 1 49 ? -12.772 32.396 2.165 1.00 87.12 ? 47 ALA B CB 1 ATOM 3678 N N . GLU B 1 50 ? -14.647 32.134 -0.367 1.00 84.29 ? 48 GLU B N 1 ATOM 3679 C CA . GLU B 1 50 ? -15.780 31.463 -1.044 1.00 82.82 ? 48 GLU B CA 1 ATOM 3680 C C . GLU B 1 50 ? -15.943 31.783 -2.550 1.00 81.96 ? 48 GLU B C 1 ATOM 3681 O O . GLU B 1 50 ? -15.554 32.862 -3.011 1.00 81.98 ? 48 GLU B O 1 ATOM 3682 C CB . GLU B 1 50 ? -17.094 31.752 -0.296 1.00 84.15 ? 48 GLU B CB 1 ATOM 3683 C CG . GLU B 1 50 ? -18.110 30.625 -0.360 1.00 94.75 ? 48 GLU B CG 1 ATOM 3684 C CD . GLU B 1 50 ? -19.165 30.698 0.725 1.00 122.85 ? 48 GLU B CD 1 ATOM 3685 O OE1 . GLU B 1 50 ? -20.027 31.608 0.668 1.00 117.35 ? 48 GLU B OE1 1 ATOM 3686 O OE2 . GLU B 1 50 ? -19.118 29.850 1.646 1.00 119.19 ? 48 GLU B OE2 1 ATOM 3687 N N . ASP B 1 51 ? -16.544 30.827 -3.296 1.00 73.57 ? 49 ASP B N 1 ATOM 3688 C CA . ASP B 1 51 ? -16.833 30.905 -4.727 1.00 71.28 ? 49 ASP B CA 1 ATOM 3689 C C . ASP B 1 51 ? -18.004 31.848 -5.019 1.00 68.22 ? 49 ASP B C 1 ATOM 3690 O O . ASP B 1 51 ? -17.875 32.752 -5.844 1.00 68.26 ? 49 ASP B O 1 ATOM 3691 C CB . ASP B 1 51 ? -17.175 29.500 -5.266 1.00 73.96 ? 49 ASP B CB 1 ATOM 3692 C CG . ASP B 1 51 ? -16.020 28.515 -5.358 1.00 86.83 ? 49 ASP B CG 1 ATOM 3693 O OD1 . ASP B 1 51 ? -14.844 28.959 -5.276 1.00 85.73 ? 49 ASP B OD1 1 ATOM 3694 O OD2 . ASP B 1 51 ? -16.287 27.313 -5.594 1.00 95.47 ? 49 ASP B OD2 1 ATOM 3695 N N . CYS B 1 52 ? -19.153 31.627 -4.359 1.00 59.12 ? 50 CYS B N 1 ATOM 3696 C CA . CYS B 1 52 ? -20.362 32.419 -4.596 1.00 55.72 ? 50 CYS B CA 1 ATOM 3697 C C . CYS B 1 52 ? -20.772 33.304 -3.435 1.00 58.16 ? 50 CYS B C 1 ATOM 3698 O O . CYS B 1 52 ? -20.660 32.916 -2.273 1.00 57.24 ? 50 CYS B O 1 ATOM 3699 C CB . CYS B 1 52 ? -21.507 31.514 -5.033 1.00 53.90 ? 50 CYS B CB 1 ATOM 3700 S SG . CYS B 1 52 ? -21.053 30.380 -6.368 1.00 56.44 ? 50 CYS B SG 1 ATOM 3701 N N . GLY B 1 53 ? -21.241 34.493 -3.787 1.00 54.66 ? 51 GLY B N 1 ATOM 3702 C CA . GLY B 1 53 ? -21.735 35.492 -2.850 1.00 54.09 ? 51 GLY B CA 1 ATOM 3703 C C . GLY B 1 53 ? -23.239 35.409 -2.685 1.00 56.23 ? 51 GLY B C 1 ATOM 3704 O O . GLY B 1 53 ? -23.826 34.345 -2.907 1.00 54.52 ? 51 GLY B O 1 ATOM 3705 N N . PRO B 1 54 ? -23.896 36.512 -2.265 1.00 53.48 ? 52 PRO B N 1 ATOM 3706 C CA . PRO B 1 54 ? -25.371 36.477 -2.122 1.00 52.42 ? 52 PRO B CA 1 ATOM 3707 C C . PRO B 1 54 ? -26.079 36.563 -3.481 1.00 56.85 ? 52 PRO B C 1 ATOM 3708 O O . PRO B 1 54 ? -25.475 36.942 -4.491 1.00 56.22 ? 52 PRO B O 1 ATOM 3709 C CB . PRO B 1 54 ? -25.690 37.703 -1.250 1.00 53.22 ? 52 PRO B CB 1 ATOM 3710 C CG . PRO B 1 54 ? -24.376 38.397 -1.002 1.00 57.93 ? 52 PRO B CG 1 ATOM 3711 C CD . PRO B 1 54 ? -23.355 37.850 -1.945 1.00 54.32 ? 52 PRO B CD 1 ATOM 3712 N N . VAL B 1 55 ? -27.367 36.217 -3.483 1.00 53.53 ? 53 VAL B N 1 ATOM 3713 C CA . VAL B 1 55 ? -28.292 36.213 -4.618 1.00 52.69 ? 53 VAL B CA 1 ATOM 3714 C C . VAL B 1 55 ? -28.382 37.599 -5.312 1.00 55.42 ? 53 VAL B C 1 ATOM 3715 O O . VAL B 1 55 ? -28.329 38.634 -4.646 1.00 55.18 ? 53 VAL B O 1 ATOM 3716 C CB . VAL B 1 55 ? -29.680 35.711 -4.130 1.00 55.88 ? 53 VAL B CB 1 ATOM 3717 C CG1 . VAL B 1 55 ? -30.733 35.826 -5.216 1.00 56.23 ? 53 VAL B CG1 1 ATOM 3718 C CG2 . VAL B 1 55 ? -29.600 34.275 -3.638 1.00 55.43 ? 53 VAL B CG2 1 ATOM 3719 N N . ASN B 1 56 ? -28.506 37.588 -6.653 1.00 51.16 ? 54 ASN B N 1 ATOM 3720 C CA . ASN B 1 56 ? -28.678 38.739 -7.546 1.00 50.77 ? 54 ASN B CA 1 ATOM 3721 C C . ASN B 1 56 ? -30.149 38.810 -7.933 1.00 55.22 ? 54 ASN B C 1 ATOM 3722 O O . ASN B 1 56 ? -30.604 38.000 -8.755 1.00 55.44 ? 54 ASN B O 1 ATOM 3723 C CB . ASN B 1 56 ? -27.903 38.495 -8.796 1.00 48.90 ? 54 ASN B CB 1 ATOM 3724 C CG . ASN B 1 56 ? -26.769 39.405 -9.052 1.00 66.98 ? 54 ASN B CG 1 ATOM 3725 O OD1 . ASN B 1 56 ? -26.440 40.285 -8.253 1.00 72.44 ? 54 ASN B OD1 1 ATOM 3726 N ND2 . ASN B 1 56 ? -26.134 39.173 -10.188 1.00 47.97 ? 54 ASN B ND2 1 ATOM 3727 N N . GLU B 1 57 ? -30.904 39.735 -7.324 1.00 51.19 ? 55 GLU B N 1 ATOM 3728 C CA . GLU B 1 57 ? -32.336 39.859 -7.590 1.00 51.14 ? 55 GLU B CA 1 ATOM 3729 C C . GLU B 1 57 ? -32.666 40.210 -9.044 1.00 55.53 ? 55 GLU B C 1 ATOM 3730 O O . GLU B 1 57 ? -33.493 39.542 -9.672 1.00 55.54 ? 55 GLU B O 1 ATOM 3731 C CB . GLU B 1 57 ? -33.003 40.855 -6.623 1.00 52.49 ? 55 GLU B CB 1 ATOM 3732 C CG . GLU B 1 57 ? -34.503 40.995 -6.862 1.00 65.22 ? 55 GLU B CG 1 ATOM 3733 C CD . GLU B 1 57 ? -35.316 41.829 -5.894 1.00 86.05 ? 55 GLU B CD 1 ATOM 3734 O OE1 . GLU B 1 57 ? -36.564 41.722 -5.938 1.00 76.99 ? 55 GLU B OE1 1 ATOM 3735 O OE2 . GLU B 1 57 ? -34.716 42.598 -5.106 1.00 75.00 ? 55 GLU B OE2 1 ATOM 3736 N N . HIS B 1 58 ? -32.007 41.241 -9.571 1.00 51.54 ? 56 HIS B N 1 ATOM 3737 C CA . HIS B 1 58 ? -32.290 41.791 -10.896 1.00 50.86 ? 56 HIS B CA 1 ATOM 3738 C C . HIS B 1 58 ? -31.554 41.082 -12.052 1.00 50.02 ? 56 HIS B C 1 ATOM 3739 O O . HIS B 1 58 ? -32.228 40.472 -12.886 1.00 48.83 ? 56 HIS B O 1 ATOM 3740 C CB . HIS B 1 58 ? -32.041 43.307 -10.864 1.00 51.67 ? 56 HIS B CB 1 ATOM 3741 C CG . HIS B 1 58 ? -32.717 43.926 -9.679 1.00 55.02 ? 56 HIS B CG 1 ATOM 3742 N ND1 . HIS B 1 58 ? -34.102 44.036 -9.612 1.00 56.49 ? 56 HIS B ND1 1 ATOM 3743 C CD2 . HIS B 1 58 ? -32.189 44.337 -8.500 1.00 56.72 ? 56 HIS B CD2 1 ATOM 3744 C CE1 . HIS B 1 58 ? -34.359 44.559 -8.423 1.00 55.91 ? 56 HIS B CE1 1 ATOM 3745 N NE2 . HIS B 1 58 ? -33.240 44.758 -7.718 1.00 56.16 ? 56 HIS B NE2 1 ATOM 3746 N N . ARG B 1 59 ? -30.202 41.120 -12.085 1.00 43.08 ? 57 ARG B N 1 ATOM 3747 C CA . ARG B 1 59 ? -29.419 40.455 -13.127 1.00 42.39 ? 57 ARG B CA 1 ATOM 3748 C C . ARG B 1 59 ? -29.349 38.879 -12.992 1.00 45.44 ? 57 ARG B C 1 ATOM 3749 O O . ARG B 1 59 ? -28.956 38.184 -13.928 1.00 44.86 ? 57 ARG B O 1 ATOM 3750 C CB . ARG B 1 59 ? -28.022 41.073 -13.226 1.00 42.26 ? 57 ARG B CB 1 ATOM 3751 C CG . ARG B 1 59 ? -28.026 42.439 -13.855 1.00 45.09 ? 57 ARG B CG 1 ATOM 3752 C CD . ARG B 1 59 ? -26.645 42.995 -14.129 1.00 51.13 ? 57 ARG B CD 1 ATOM 3753 N NE . ARG B 1 59 ? -26.745 44.132 -15.054 1.00 64.75 ? 57 ARG B NE 1 ATOM 3754 C CZ . ARG B 1 59 ? -26.321 45.368 -14.806 1.00 67.90 ? 57 ARG B CZ 1 ATOM 3755 N NH1 . ARG B 1 59 ? -25.716 45.653 -13.658 1.00 35.81 ? 57 ARG B NH1 1 ATOM 3756 N NH2 . ARG B 1 59 ? -26.492 46.329 -15.709 1.00 53.14 ? 57 ARG B NH2 1 ATOM 3757 N N . GLY B 1 60 ? -29.757 38.349 -11.855 1.00 40.72 ? 58 GLY B N 1 ATOM 3758 C CA . GLY B 1 60 ? -29.744 36.924 -11.613 1.00 39.58 ? 58 GLY B CA 1 ATOM 3759 C C . GLY B 1 60 ? -31.114 36.324 -11.773 1.00 42.65 ? 58 GLY B C 1 ATOM 3760 O O . GLY B 1 60 ? -31.448 35.847 -12.857 1.00 43.41 ? 58 GLY B O 1 ATOM 3761 N N . ILE B 1 61 ? -31.928 36.383 -10.704 1.00 37.79 ? 59 ILE B N 1 ATOM 3762 C CA . ILE B 1 61 ? -33.252 35.761 -10.627 1.00 36.91 ? 59 ILE B CA 1 ATOM 3763 C C . ILE B 1 61 ? -34.224 36.230 -11.702 1.00 42.56 ? 59 ILE B C 1 ATOM 3764 O O . ILE B 1 61 ? -34.848 35.392 -12.378 1.00 42.62 ? 59 ILE B O 1 ATOM 3765 C CB . ILE B 1 61 ? -33.833 35.908 -9.210 1.00 39.67 ? 59 ILE B CB 1 ATOM 3766 C CG1 . ILE B 1 61 ? -32.936 35.163 -8.178 1.00 40.20 ? 59 ILE B CG1 1 ATOM 3767 C CG2 . ILE B 1 61 ? -35.293 35.430 -9.126 1.00 39.29 ? 59 ILE B CG2 1 ATOM 3768 C CD1 . ILE B 1 61 ? -32.684 33.587 -8.427 1.00 35.00 ? 59 ILE B CD1 1 ATOM 3769 N N . GLN B 1 62 ? -34.356 37.546 -11.861 1.00 40.84 ? 60 GLN B N 1 ATOM 3770 C CA . GLN B 1 62 ? -35.274 38.125 -12.828 1.00 41.77 ? 60 GLN B CA 1 ATOM 3771 C C . GLN B 1 62 ? -34.880 37.705 -14.260 1.00 48.32 ? 60 GLN B C 1 ATOM 3772 O O . GLN B 1 62 ? -35.748 37.260 -15.036 1.00 48.35 ? 60 GLN B O 1 ATOM 3773 C CB . GLN B 1 62 ? -35.317 39.639 -12.659 1.00 42.90 ? 60 GLN B CB 1 ATOM 3774 C CG . GLN B 1 62 ? -36.702 40.230 -12.491 1.00 47.17 ? 60 GLN B CG 1 ATOM 3775 C CD . GLN B 1 62 ? -36.614 41.725 -12.689 1.00 57.09 ? 60 GLN B CD 1 ATOM 3776 O OE1 . GLN B 1 62 ? -36.585 42.222 -13.808 1.00 48.65 ? 60 GLN B OE1 1 ATOM 3777 N NE2 . GLN B 1 62 ? -36.500 42.475 -11.614 1.00 54.76 ? 60 GLN B NE2 1 ATOM 3778 N N . ARG B 1 63 ? -33.563 37.721 -14.565 1.00 44.33 ? 61 ARG B N 1 ATOM 3779 C CA . ARG B 1 63 ? -33.107 37.312 -15.897 1.00 43.97 ? 61 ARG B CA 1 ATOM 3780 C C . ARG B 1 63 ? -33.312 35.825 -16.173 1.00 47.12 ? 61 ARG B C 1 ATOM 3781 O O . ARG B 1 63 ? -33.661 35.454 -17.293 1.00 45.98 ? 61 ARG B O 1 ATOM 3782 C CB . ARG B 1 63 ? -31.671 37.743 -16.160 1.00 42.29 ? 61 ARG B CB 1 ATOM 3783 C CG . ARG B 1 63 ? -31.586 39.197 -16.548 1.00 46.57 ? 61 ARG B CG 1 ATOM 3784 C CD . ARG B 1 63 ? -30.157 39.509 -16.797 1.00 49.04 ? 61 ARG B CD 1 ATOM 3785 N NE . ARG B 1 63 ? -29.908 40.936 -16.918 1.00 40.54 ? 61 ARG B NE 1 ATOM 3786 C CZ . ARG B 1 63 ? -28.703 41.445 -17.154 1.00 58.58 ? 61 ARG B CZ 1 ATOM 3787 N NH1 . ARG B 1 63 ? -27.646 40.642 -17.279 1.00 46.50 ? 61 ARG B NH1 1 ATOM 3788 N NH2 . ARG B 1 63 ? -28.544 42.756 -17.274 1.00 37.41 ? 61 ARG B NH2 1 ATOM 3789 N N . LEU B 1 64 ? -33.123 34.987 -15.154 1.00 43.49 ? 62 LEU B N 1 ATOM 3790 C CA . LEU B 1 64 ? -33.309 33.546 -15.274 1.00 43.14 ? 62 LEU B CA 1 ATOM 3791 C C . LEU B 1 64 ? -34.807 33.261 -15.456 1.00 43.37 ? 62 LEU B C 1 ATOM 3792 O O . LEU B 1 64 ? -35.172 32.336 -16.174 1.00 41.51 ? 62 LEU B O 1 ATOM 3793 C CB . LEU B 1 64 ? -32.761 32.864 -13.997 1.00 43.78 ? 62 LEU B CB 1 ATOM 3794 C CG . LEU B 1 64 ? -33.052 31.370 -13.776 1.00 48.70 ? 62 LEU B CG 1 ATOM 3795 C CD1 . LEU B 1 64 ? -31.984 30.764 -12.935 1.00 49.56 ? 62 LEU B CD1 1 ATOM 3796 C CD2 . LEU B 1 64 ? -34.368 31.162 -13.041 1.00 50.36 ? 62 LEU B CD2 1 ATOM 3797 N N . GLU B 1 65 ? -35.668 34.016 -14.759 1.00 38.97 ? 63 GLU B N 1 ATOM 3798 C CA . GLU B 1 65 ? -37.124 33.778 -14.855 1.00 37.36 ? 63 GLU B CA 1 ATOM 3799 C C . GLU B 1 65 ? -37.665 34.220 -16.207 1.00 37.75 ? 63 GLU B C 1 ATOM 3800 O O . GLU B 1 65 ? -38.526 33.536 -16.733 1.00 36.98 ? 63 GLU B O 1 ATOM 3801 C CB . GLU B 1 65 ? -37.897 34.365 -13.655 1.00 38.10 ? 63 GLU B CB 1 ATOM 3802 C CG . GLU B 1 65 ? -37.590 33.649 -12.340 1.00 39.88 ? 63 GLU B CG 1 ATOM 3803 C CD . GLU B 1 65 ? -38.174 32.255 -12.147 1.00 58.79 ? 63 GLU B CD 1 ATOM 3804 O OE1 . GLU B 1 65 ? -38.979 31.810 -12.996 1.00 46.92 ? 63 GLU B OE1 1 ATOM 3805 O OE2 . GLU B 1 65 ? -37.832 31.607 -11.132 1.00 52.42 ? 63 GLU B OE2 1 ATOM 3806 N N . ALA B 1 66 ? -37.074 35.277 -16.827 1.00 33.88 ? 64 ALA B N 1 ATOM 3807 C CA . ALA B 1 66 ? -37.406 35.700 -18.198 1.00 33.13 ? 64 ALA B CA 1 ATOM 3808 C C . ALA B 1 66 ? -37.166 34.551 -19.194 1.00 36.03 ? 64 ALA B C 1 ATOM 3809 O O . ALA B 1 66 ? -38.037 34.289 -20.026 1.00 36.25 ? 64 ALA B O 1 ATOM 3810 C CB . ALA B 1 66 ? -36.618 36.936 -18.586 1.00 33.89 ? 64 ALA B CB 1 ATOM 3811 N N . MET B 1 67 ? -36.050 33.800 -19.037 1.00 32.42 ? 65 MET B N 1 ATOM 3812 C CA . MET B 1 67 ? -35.774 32.585 -19.810 1.00 32.62 ? 65 MET B CA 1 ATOM 3813 C C . MET B 1 67 ? -36.921 31.557 -19.630 1.00 36.92 ? 65 MET B C 1 ATOM 3814 O O . MET B 1 67 ? -37.480 31.106 -20.627 1.00 38.27 ? 65 MET B O 1 ATOM 3815 C CB . MET B 1 67 ? -34.391 31.971 -19.460 1.00 34.92 ? 65 MET B CB 1 ATOM 3816 C CG . MET B 1 67 ? -34.118 30.634 -20.150 1.00 39.46 ? 65 MET B CG 1 ATOM 3817 S SD . MET B 1 67 ? -32.373 30.363 -20.565 1.00 44.98 ? 65 MET B SD 1 ATOM 3818 C CE . MET B 1 67 ? -32.451 28.659 -21.275 1.00 40.52 ? 65 MET B CE 1 ATOM 3819 N N . LEU B 1 68 ? -37.314 31.257 -18.380 1.00 33.53 ? 66 LEU B N 1 ATOM 3820 C CA . LEU B 1 68 ? -38.389 30.295 -18.055 1.00 34.07 ? 66 LEU B CA 1 ATOM 3821 C C . LEU B 1 68 ? -39.760 30.713 -18.608 1.00 41.71 ? 66 LEU B C 1 ATOM 3822 O O . LEU B 1 68 ? -40.505 29.875 -19.132 1.00 39.08 ? 66 LEU B O 1 ATOM 3823 C CB . LEU B 1 68 ? -38.488 30.007 -16.544 1.00 33.26 ? 66 LEU B CB 1 ATOM 3824 C CG . LEU B 1 68 ? -37.247 29.445 -15.858 1.00 37.34 ? 66 LEU B CG 1 ATOM 3825 C CD1 . LEU B 1 68 ? -37.597 28.926 -14.443 1.00 37.48 ? 66 LEU B CD1 1 ATOM 3826 C CD2 . LEU B 1 68 ? -36.606 28.356 -16.682 1.00 36.95 ? 66 LEU B CD2 1 ATOM 3827 N N . PHE B 1 69 ? -40.075 32.010 -18.465 1.00 42.09 ? 67 PHE B N 1 ATOM 3828 C CA . PHE B 1 69 ? -41.278 32.652 -18.966 1.00 44.06 ? 67 PHE B CA 1 ATOM 3829 C C . PHE B 1 69 ? -41.310 32.453 -20.478 1.00 47.55 ? 67 PHE B C 1 ATOM 3830 O O . PHE B 1 69 ? -42.316 31.972 -21.008 1.00 46.39 ? 67 PHE B O 1 ATOM 3831 C CB . PHE B 1 69 ? -41.199 34.155 -18.634 1.00 47.26 ? 67 PHE B CB 1 ATOM 3832 C CG . PHE B 1 69 ? -42.024 35.106 -19.476 1.00 50.44 ? 67 PHE B CG 1 ATOM 3833 C CD1 . PHE B 1 69 ? -43.352 35.387 -19.143 1.00 54.70 ? 67 PHE B CD1 1 ATOM 3834 C CD2 . PHE B 1 69 ? -41.443 35.814 -20.529 1.00 51.67 ? 67 PHE B CD2 1 ATOM 3835 C CE1 . PHE B 1 69 ? -44.094 36.327 -19.879 1.00 54.65 ? 67 PHE B CE1 1 ATOM 3836 C CE2 . PHE B 1 69 ? -42.185 36.753 -21.256 1.00 53.80 ? 67 PHE B CE2 1 ATOM 3837 C CZ . PHE B 1 69 ? -43.503 36.999 -20.928 1.00 52.24 ? 67 PHE B CZ 1 ATOM 3838 N N . ALA B 1 70 ? -40.182 32.814 -21.162 1.00 43.81 ? 68 ALA B N 1 ATOM 3839 C CA . ALA B 1 70 ? -40.045 32.734 -22.626 1.00 42.75 ? 68 ALA B CA 1 ATOM 3840 C C . ALA B 1 70 ? -40.274 31.327 -23.112 1.00 45.34 ? 68 ALA B C 1 ATOM 3841 O O . ALA B 1 70 ? -41.077 31.160 -24.016 1.00 44.36 ? 68 ALA B O 1 ATOM 3842 C CB . ALA B 1 70 ? -38.688 33.258 -23.085 1.00 42.89 ? 68 ALA B CB 1 ATOM 3843 N N . LEU B 1 71 ? -39.665 30.308 -22.448 1.00 41.20 ? 69 LEU B N 1 ATOM 3844 C CA . LEU B 1 71 ? -39.827 28.906 -22.838 1.00 40.41 ? 69 LEU B CA 1 ATOM 3845 C C . LEU B 1 71 ? -41.248 28.441 -22.634 1.00 47.12 ? 69 LEU B C 1 ATOM 3846 O O . LEU B 1 71 ? -41.715 27.584 -23.377 1.00 48.05 ? 69 LEU B O 1 ATOM 3847 C CB . LEU B 1 71 ? -38.872 27.979 -22.068 1.00 39.71 ? 69 LEU B CB 1 ATOM 3848 C CG . LEU B 1 71 ? -37.394 28.108 -22.355 1.00 43.79 ? 69 LEU B CG 1 ATOM 3849 C CD1 . LEU B 1 71 ? -36.604 27.376 -21.330 1.00 44.42 ? 69 LEU B CD1 1 ATOM 3850 C CD2 . LEU B 1 71 ? -37.030 27.578 -23.723 1.00 45.27 ? 69 LEU B CD2 1 ATOM 3851 N N . ASP B 1 72 ? -41.928 28.980 -21.606 1.00 44.19 ? 70 ASP B N 1 ATOM 3852 C CA . ASP B 1 72 ? -43.310 28.636 -21.302 1.00 44.37 ? 70 ASP B CA 1 ATOM 3853 C C . ASP B 1 72 ? -44.195 29.107 -22.442 1.00 49.53 ? 70 ASP B C 1 ATOM 3854 O O . ASP B 1 72 ? -44.860 28.269 -23.059 1.00 50.74 ? 70 ASP B O 1 ATOM 3855 C CB . ASP B 1 72 ? -43.753 29.173 -19.916 1.00 45.70 ? 70 ASP B CB 1 ATOM 3856 C CG . ASP B 1 72 ? -43.269 28.337 -18.728 1.00 56.74 ? 70 ASP B CG 1 ATOM 3857 O OD1 . ASP B 1 72 ? -42.894 27.153 -18.935 1.00 56.03 ? 70 ASP B OD1 1 ATOM 3858 O OD2 . ASP B 1 72 ? -43.254 28.867 -17.598 1.00 66.23 ? 70 ASP B OD2 1 ATOM 3859 N N . ARG B 1 73 ? -44.101 30.398 -22.804 1.00 45.50 ? 71 ARG B N 1 ATOM 3860 C CA . ARG B 1 73 ? -44.827 30.964 -23.941 1.00 46.40 ? 71 ARG B CA 1 ATOM 3861 C C . ARG B 1 73 ? -44.525 30.175 -25.240 1.00 51.57 ? 71 ARG B C 1 ATOM 3862 O O . ARG B 1 73 ? -45.456 29.680 -25.869 1.00 51.08 ? 71 ARG B O 1 ATOM 3863 C CB . ARG B 1 73 ? -44.524 32.466 -24.113 1.00 46.27 ? 71 ARG B CB 1 ATOM 3864 C CG . ARG B 1 73 ? -44.930 33.347 -22.941 1.00 56.28 ? 71 ARG B CG 1 ATOM 3865 C CD . ARG B 1 73 ? -46.430 33.366 -22.675 1.00 70.88 ? 71 ARG B CD 1 ATOM 3866 N NE . ARG B 1 73 ? -47.157 34.338 -23.499 1.00 88.00 ? 71 ARG B NE 1 ATOM 3867 C CZ . ARG B 1 73 ? -47.784 35.412 -23.020 1.00 102.22 ? 71 ARG B CZ 1 ATOM 3868 N NH1 . ARG B 1 73 ? -47.773 35.673 -21.717 1.00 80.31 ? 71 ARG B NH1 1 ATOM 3869 N NH2 . ARG B 1 73 ? -48.423 36.234 -23.841 1.00 97.72 ? 71 ARG B NH2 1 ATOM 3870 N N . ILE B 1 74 ? -43.220 29.993 -25.583 1.00 47.24 ? 72 ILE B N 1 ATOM 3871 C CA . ILE B 1 74 ? -42.745 29.235 -26.746 1.00 45.54 ? 72 ILE B CA 1 ATOM 3872 C C . ILE B 1 74 ? -43.417 27.845 -26.810 1.00 50.63 ? 72 ILE B C 1 ATOM 3873 O O . ILE B 1 74 ? -43.877 27.437 -27.883 1.00 51.31 ? 72 ILE B O 1 ATOM 3874 C CB . ILE B 1 74 ? -41.181 29.178 -26.798 1.00 47.02 ? 72 ILE B CB 1 ATOM 3875 C CG1 . ILE B 1 74 ? -40.585 30.558 -27.190 1.00 46.31 ? 72 ILE B CG1 1 ATOM 3876 C CG2 . ILE B 1 74 ? -40.671 28.064 -27.738 1.00 45.73 ? 72 ILE B CG2 1 ATOM 3877 C CD1 . ILE B 1 74 ? -39.119 30.796 -26.846 1.00 41.19 ? 72 ILE B CD1 1 ATOM 3878 N N . ASN B 1 75 ? -43.515 27.157 -25.665 1.00 47.53 ? 73 ASN B N 1 ATOM 3879 C CA . ASN B 1 75 ? -44.133 25.830 -25.576 1.00 47.79 ? 73 ASN B CA 1 ATOM 3880 C C . ASN B 1 75 ? -45.682 25.859 -25.659 1.00 54.20 ? 73 ASN B C 1 ATOM 3881 O O . ASN B 1 75 ? -46.293 24.816 -25.857 1.00 53.99 ? 73 ASN B O 1 ATOM 3882 C CB . ASN B 1 75 ? -43.646 25.084 -24.360 1.00 43.28 ? 73 ASN B CB 1 ATOM 3883 C CG . ASN B 1 75 ? -42.184 24.695 -24.409 1.00 44.74 ? 73 ASN B CG 1 ATOM 3884 O OD1 . ASN B 1 75 ? -41.613 24.380 -25.464 1.00 41.92 ? 73 ASN B OD1 1 ATOM 3885 N ND2 . ASN B 1 75 ? -41.585 24.577 -23.240 1.00 26.35 ? 73 ASN B ND2 1 ATOM 3886 N N . ARG B 1 76 ? -46.292 27.052 -25.590 1.00 52.11 ? 74 ARG B N 1 ATOM 3887 C CA . ARG B 1 76 ? -47.738 27.287 -25.762 1.00 52.33 ? 74 ARG B CA 1 ATOM 3888 C C . ARG B 1 76 ? -47.983 28.067 -27.090 1.00 56.56 ? 74 ARG B C 1 ATOM 3889 O O . ARG B 1 76 ? -49.103 28.507 -27.341 1.00 54.27 ? 74 ARG B O 1 ATOM 3890 C CB . ARG B 1 76 ? -48.296 28.113 -24.581 1.00 51.69 ? 74 ARG B CB 1 ATOM 3891 C CG . ARG B 1 76 ? -48.631 27.296 -23.343 1.00 58.95 ? 74 ARG B CG 1 ATOM 3892 C CD . ARG B 1 76 ? -49.534 28.063 -22.395 1.00 76.84 ? 74 ARG B CD 1 ATOM 3893 N NE . ARG B 1 76 ? -48.805 29.087 -21.640 1.00 95.35 ? 74 ARG B NE 1 ATOM 3894 C CZ . ARG B 1 76 ? -48.859 30.397 -21.877 1.00 102.85 ? 74 ARG B CZ 1 ATOM 3895 N NH1 . ARG B 1 76 ? -49.621 30.874 -22.858 1.00 82.14 ? 74 ARG B NH1 1 ATOM 3896 N NH2 . ARG B 1 76 ? -48.164 31.239 -21.127 1.00 84.74 ? 74 ARG B NH2 1 ATOM 3897 N N . ASP B 1 77 ? -46.912 28.291 -27.898 1.00 56.02 ? 75 ASP B N 1 ATOM 3898 C CA . ASP B 1 77 ? -46.961 29.015 -29.185 1.00 56.18 ? 75 ASP B CA 1 ATOM 3899 C C . ASP B 1 77 ? -47.237 27.985 -30.280 1.00 61.16 ? 75 ASP B C 1 ATOM 3900 O O . ASP B 1 77 ? -46.512 26.979 -30.363 1.00 60.12 ? 75 ASP B O 1 ATOM 3901 C CB . ASP B 1 77 ? -45.663 29.810 -29.451 1.00 57.37 ? 75 ASP B CB 1 ATOM 3902 C CG . ASP B 1 77 ? -45.824 31.004 -30.370 1.00 64.44 ? 75 ASP B CG 1 ATOM 3903 O OD1 . ASP B 1 77 ? -46.389 30.832 -31.466 1.00 65.46 ? 75 ASP B OD1 1 ATOM 3904 O OD2 . ASP B 1 77 ? -45.340 32.108 -30.006 1.00 66.79 ? 75 ASP B OD2 1 ATOM 3905 N N . PRO B 1 78 ? -48.360 28.143 -31.028 1.00 59.04 ? 76 PRO B N 1 ATOM 3906 C CA . PRO B 1 78 ? -48.718 27.123 -32.026 1.00 58.81 ? 76 PRO B CA 1 ATOM 3907 C C . PRO B 1 78 ? -47.878 27.177 -33.304 1.00 62.45 ? 76 PRO B C 1 ATOM 3908 O O . PRO B 1 78 ? -47.643 26.136 -33.923 1.00 61.17 ? 76 PRO B O 1 ATOM 3909 C CB . PRO B 1 78 ? -50.201 27.390 -32.272 1.00 60.08 ? 76 PRO B CB 1 ATOM 3910 C CG . PRO B 1 78 ? -50.357 28.841 -32.043 1.00 64.60 ? 76 PRO B CG 1 ATOM 3911 C CD . PRO B 1 78 ? -49.348 29.247 -31.011 1.00 60.46 ? 76 PRO B CD 1 ATOM 3912 N N . HIS B 1 79 ? -47.408 28.384 -33.669 1.00 58.64 ? 77 HIS B N 1 ATOM 3913 C CA . HIS B 1 79 ? -46.620 28.642 -34.863 1.00 59.07 ? 77 HIS B CA 1 ATOM 3914 C C . HIS B 1 79 ? -45.099 28.493 -34.644 1.00 60.65 ? 77 HIS B C 1 ATOM 3915 O O . HIS B 1 79 ? -44.334 28.689 -35.594 1.00 61.79 ? 77 HIS B O 1 ATOM 3916 C CB . HIS B 1 79 ? -46.956 30.044 -35.411 1.00 61.19 ? 77 HIS B CB 1 ATOM 3917 C CG . HIS B 1 79 ? -48.426 30.336 -35.524 1.00 66.07 ? 77 HIS B CG 1 ATOM 3918 N ND1 . HIS B 1 79 ? -48.909 31.640 -35.456 1.00 68.70 ? 77 HIS B ND1 1 ATOM 3919 C CD2 . HIS B 1 79 ? -49.476 29.494 -35.682 1.00 68.60 ? 77 HIS B CD2 1 ATOM 3920 C CE1 . HIS B 1 79 ? -50.226 31.545 -35.564 1.00 68.29 ? 77 HIS B CE1 1 ATOM 3921 N NE2 . HIS B 1 79 ? -50.615 30.275 -35.695 1.00 68.68 ? 77 HIS B NE2 1 ATOM 3922 N N . LEU B 1 80 ? -44.662 28.144 -33.409 1.00 52.55 ? 78 LEU B N 1 ATOM 3923 C CA . LEU B 1 80 ? -43.250 28.009 -33.047 1.00 50.24 ? 78 LEU B CA 1 ATOM 3924 C C . LEU B 1 80 ? -42.993 26.673 -32.357 1.00 55.25 ? 78 LEU B C 1 ATOM 3925 O O . LEU B 1 80 ? -43.397 26.466 -31.218 1.00 55.49 ? 78 LEU B O 1 ATOM 3926 C CB . LEU B 1 80 ? -42.834 29.215 -32.177 1.00 49.25 ? 78 LEU B CB 1 ATOM 3927 C CG . LEU B 1 80 ? -41.348 29.580 -32.007 1.00 51.26 ? 78 LEU B CG 1 ATOM 3928 C CD1 . LEU B 1 80 ? -40.613 29.703 -33.342 1.00 49.36 ? 78 LEU B CD1 1 ATOM 3929 C CD2 . LEU B 1 80 ? -41.232 30.900 -31.272 1.00 51.52 ? 78 LEU B CD2 1 ATOM 3930 N N . LEU B 1 81 ? -42.359 25.749 -33.079 1.00 53.49 ? 79 LEU B N 1 ATOM 3931 C CA . LEU B 1 81 ? -42.069 24.378 -32.647 1.00 54.07 ? 79 LEU B CA 1 ATOM 3932 C C . LEU B 1 81 ? -43.285 23.694 -31.950 1.00 61.39 ? 79 LEU B C 1 ATOM 3933 O O . LEU B 1 81 ? -43.148 23.293 -30.790 1.00 62.51 ? 79 LEU B O 1 ATOM 3934 C CB . LEU B 1 81 ? -40.792 24.305 -31.773 1.00 53.38 ? 79 LEU B CB 1 ATOM 3935 C CG . LEU B 1 81 ? -39.471 24.567 -32.463 1.00 56.61 ? 79 LEU B CG 1 ATOM 3936 C CD1 . LEU B 1 81 ? -38.415 25.033 -31.453 1.00 55.11 ? 79 LEU B CD1 1 ATOM 3937 C CD2 . LEU B 1 81 ? -39.024 23.351 -33.297 1.00 57.08 ? 79 LEU B CD2 1 ATOM 3938 N N . PRO B 1 82 ? -44.473 23.545 -32.609 1.00 57.91 ? 80 PRO B N 1 ATOM 3939 C CA . PRO B 1 82 ? -45.613 22.903 -31.922 1.00 57.36 ? 80 PRO B CA 1 ATOM 3940 C C . PRO B 1 82 ? -45.418 21.419 -31.563 1.00 59.96 ? 80 PRO B C 1 ATOM 3941 O O . PRO B 1 82 ? -46.034 20.936 -30.608 1.00 61.09 ? 80 PRO B O 1 ATOM 3942 C CB . PRO B 1 82 ? -46.782 23.122 -32.889 1.00 58.89 ? 80 PRO B CB 1 ATOM 3943 C CG . PRO B 1 82 ? -46.158 23.234 -34.207 1.00 63.34 ? 80 PRO B CG 1 ATOM 3944 C CD . PRO B 1 82 ? -44.855 23.951 -33.978 1.00 59.39 ? 80 PRO B CD 1 ATOM 3945 N N . GLY B 1 83 ? -44.560 20.725 -32.299 1.00 53.75 ? 81 GLY B N 1 ATOM 3946 C CA . GLY B 1 83 ? -44.294 19.315 -32.059 1.00 53.32 ? 81 GLY B CA 1 ATOM 3947 C C . GLY B 1 83 ? -43.033 19.048 -31.265 1.00 58.32 ? 81 GLY B C 1 ATOM 3948 O O . GLY B 1 83 ? -42.785 17.897 -30.879 1.00 58.13 ? 81 GLY B O 1 ATOM 3949 N N . VAL B 1 84 ? -42.200 20.105 -31.024 1.00 54.17 ? 82 VAL B N 1 ATOM 3950 C CA . VAL B 1 84 ? -40.924 19.935 -30.283 1.00 52.73 ? 82 VAL B CA 1 ATOM 3951 C C . VAL B 1 84 ? -40.914 20.774 -28.975 1.00 55.23 ? 82 VAL B C 1 ATOM 3952 O O . VAL B 1 84 ? -41.062 22.001 -29.014 1.00 54.07 ? 82 VAL B O 1 ATOM 3953 C CB . VAL B 1 84 ? -39.676 20.175 -31.197 1.00 55.18 ? 82 VAL B CB 1 ATOM 3954 C CG1 . VAL B 1 84 ? -38.368 19.910 -30.457 1.00 54.47 ? 82 VAL B CG1 1 ATOM 3955 C CG2 . VAL B 1 84 ? -39.749 19.316 -32.468 1.00 54.43 ? 82 VAL B CG2 1 ATOM 3956 N N . ARG B 1 85 ? -40.821 20.086 -27.814 1.00 52.09 ? 83 ARG B N 1 ATOM 3957 C CA . ARG B 1 85 ? -40.792 20.754 -26.510 1.00 51.46 ? 83 ARG B CA 1 ATOM 3958 C C . ARG B 1 85 ? -39.394 21.237 -26.217 1.00 53.86 ? 83 ARG B C 1 ATOM 3959 O O . ARG B 1 85 ? -38.431 20.486 -26.383 1.00 52.07 ? 83 ARG B O 1 ATOM 3960 C CB . ARG B 1 85 ? -41.275 19.854 -25.355 1.00 50.68 ? 83 ARG B CB 1 ATOM 3961 C CG . ARG B 1 85 ? -41.368 20.624 -24.021 1.00 50.53 ? 83 ARG B CG 1 ATOM 3962 C CD . ARG B 1 85 ? -42.288 19.974 -23.017 1.00 53.39 ? 83 ARG B CD 1 ATOM 3963 N NE . ARG B 1 85 ? -42.981 20.979 -22.214 1.00 67.22 ? 83 ARG B NE 1 ATOM 3964 C CZ . ARG B 1 85 ? -44.123 21.573 -22.560 1.00 95.73 ? 83 ARG B CZ 1 ATOM 3965 N NH1 . ARG B 1 85 ? -44.719 21.267 -23.710 1.00 87.32 ? 83 ARG B NH1 1 ATOM 3966 N NH2 . ARG B 1 85 ? -44.676 22.479 -21.760 1.00 86.65 ? 83 ARG B NH2 1 ATOM 3967 N N . LEU B 1 86 ? -39.296 22.495 -25.762 1.00 50.51 ? 84 LEU B N 1 ATOM 3968 C CA . LEU B 1 86 ? -38.029 23.103 -25.393 1.00 50.13 ? 84 LEU B CA 1 ATOM 3969 C C . LEU B 1 86 ? -37.741 22.967 -23.914 1.00 52.92 ? 84 LEU B C 1 ATOM 3970 O O . LEU B 1 86 ? -38.405 23.583 -23.080 1.00 53.36 ? 84 LEU B O 1 ATOM 3971 C CB . LEU B 1 86 ? -37.961 24.576 -25.831 1.00 50.13 ? 84 LEU B CB 1 ATOM 3972 C CG . LEU B 1 86 ? -37.759 24.869 -27.320 1.00 53.18 ? 84 LEU B CG 1 ATOM 3973 C CD1 . LEU B 1 86 ? -37.189 26.270 -27.498 1.00 52.61 ? 84 LEU B CD1 1 ATOM 3974 C CD2 . LEU B 1 86 ? -36.867 23.822 -28.004 1.00 51.46 ? 84 LEU B CD2 1 ATOM 3975 N N . GLY B 1 87 ? -36.777 22.124 -23.610 1.00 49.21 ? 85 GLY B N 1 ATOM 3976 C CA . GLY B 1 87 ? -36.306 21.892 -22.255 1.00 50.04 ? 85 GLY B CA 1 ATOM 3977 C C . GLY B 1 87 ? -35.189 22.852 -21.868 1.00 55.38 ? 85 GLY B C 1 ATOM 3978 O O . GLY B 1 87 ? -34.745 23.666 -22.694 1.00 54.96 ? 85 GLY B O 1 ATOM 3979 N N . ALA B 1 88 ? -34.733 22.778 -20.592 1.00 50.80 ? 86 ALA B N 1 ATOM 3980 C CA . ALA B 1 88 ? -33.677 23.663 -20.085 1.00 49.22 ? 86 ALA B CA 1 ATOM 3981 C C . ALA B 1 88 ? -32.686 23.002 -19.130 1.00 49.25 ? 86 ALA B C 1 ATOM 3982 O O . ALA B 1 88 ? -32.981 21.975 -18.522 1.00 48.66 ? 86 ALA B O 1 ATOM 3983 C CB . ALA B 1 88 ? -34.295 24.886 -19.438 1.00 50.17 ? 86 ALA B CB 1 ATOM 3984 N N . HIS B 1 89 ? -31.485 23.563 -19.068 1.00 43.70 ? 87 HIS B N 1 ATOM 3985 C CA . HIS B 1 89 ? -30.391 23.147 -18.199 1.00 42.99 ? 87 HIS B CA 1 ATOM 3986 C C . HIS B 1 89 ? -29.662 24.444 -17.881 1.00 45.39 ? 87 HIS B C 1 ATOM 3987 O O . HIS B 1 89 ? -28.721 24.845 -18.582 1.00 43.96 ? 87 HIS B O 1 ATOM 3988 C CB . HIS B 1 89 ? -29.496 22.100 -18.872 1.00 43.77 ? 87 HIS B CB 1 ATOM 3989 C CG . HIS B 1 89 ? -28.542 21.432 -17.935 1.00 47.60 ? 87 HIS B CG 1 ATOM 3990 N ND1 . HIS B 1 89 ? -27.311 21.983 -17.648 1.00 49.88 ? 87 HIS B ND1 1 ATOM 3991 C CD2 . HIS B 1 89 ? -28.653 20.260 -17.277 1.00 49.67 ? 87 HIS B CD2 1 ATOM 3992 C CE1 . HIS B 1 89 ? -26.720 21.142 -16.815 1.00 49.01 ? 87 HIS B CE1 1 ATOM 3993 N NE2 . HIS B 1 89 ? -27.489 20.093 -16.559 1.00 49.38 ? 87 HIS B NE2 1 ATOM 3994 N N . ILE B 1 90 ? -30.186 25.151 -16.873 1.00 41.62 ? 88 ILE B N 1 ATOM 3995 C CA . ILE B 1 90 ? -29.704 26.478 -16.489 1.00 41.22 ? 88 ILE B CA 1 ATOM 3996 C C . ILE B 1 90 ? -28.675 26.402 -15.355 1.00 44.27 ? 88 ILE B C 1 ATOM 3997 O O . ILE B 1 90 ? -28.911 25.741 -14.350 1.00 45.46 ? 88 ILE B O 1 ATOM 3998 C CB . ILE B 1 90 ? -30.896 27.432 -16.195 1.00 43.09 ? 88 ILE B CB 1 ATOM 3999 C CG1 . ILE B 1 90 ? -31.669 27.721 -17.488 1.00 40.82 ? 88 ILE B CG1 1 ATOM 4000 C CG2 . ILE B 1 90 ? -30.435 28.742 -15.546 1.00 44.44 ? 88 ILE B CG2 1 ATOM 4001 C CD1 . ILE B 1 90 ? -33.145 27.754 -17.309 1.00 29.62 ? 88 ILE B CD1 1 ATOM 4002 N N . LEU B 1 91 ? -27.524 27.068 -15.561 1.00 38.53 ? 89 LEU B N 1 ATOM 4003 C CA . LEU B 1 91 ? -26.392 27.111 -14.650 1.00 37.73 ? 89 LEU B CA 1 ATOM 4004 C C . LEU B 1 91 ? -26.154 28.486 -14.102 1.00 41.21 ? 89 LEU B C 1 ATOM 4005 O O . LEU B 1 91 ? -26.569 29.487 -14.695 1.00 43.96 ? 89 LEU B O 1 ATOM 4006 C CB . LEU B 1 91 ? -25.106 26.599 -15.331 1.00 37.83 ? 89 LEU B CB 1 ATOM 4007 C CG . LEU B 1 91 ? -25.109 25.112 -15.727 1.00 42.26 ? 89 LEU B CG 1 ATOM 4008 C CD1 . LEU B 1 91 ? -23.943 24.794 -16.571 1.00 42.11 ? 89 LEU B CD1 1 ATOM 4009 C CD2 . LEU B 1 91 ? -25.180 24.203 -14.518 1.00 45.26 ? 89 LEU B CD2 1 ATOM 4010 N N . ASP B 1 92 ? -25.495 28.528 -12.954 1.00 33.95 ? 90 ASP B N 1 ATOM 4011 C CA . ASP B 1 92 ? -25.141 29.745 -12.275 1.00 33.36 ? 90 ASP B CA 1 ATOM 4012 C C . ASP B 1 92 ? -23.648 30.016 -12.500 1.00 38.77 ? 90 ASP B C 1 ATOM 4013 O O . ASP B 1 92 ? -22.813 29.132 -12.294 1.00 36.78 ? 90 ASP B O 1 ATOM 4014 C CB . ASP B 1 92 ? -25.473 29.606 -10.776 1.00 34.35 ? 90 ASP B CB 1 ATOM 4015 C CG . ASP B 1 92 ? -25.191 30.799 -9.865 1.00 37.33 ? 90 ASP B CG 1 ATOM 4016 O OD1 . ASP B 1 92 ? -24.875 31.913 -10.387 1.00 37.53 ? 90 ASP B OD1 1 ATOM 4017 O OD2 . ASP B 1 92 ? -25.249 30.620 -8.647 1.00 36.60 ? 90 ASP B OD2 1 ATOM 4018 N N . SER B 1 93 ? -23.318 31.244 -12.927 1.00 35.95 ? 91 SER B N 1 ATOM 4019 C CA . SER B 1 93 ? -21.936 31.628 -13.162 1.00 35.52 ? 91 SER B CA 1 ATOM 4020 C C . SER B 1 93 ? -21.264 32.141 -11.898 1.00 44.87 ? 91 SER B C 1 ATOM 4021 O O . SER B 1 93 ? -20.040 32.141 -11.828 1.00 43.40 ? 91 SER B O 1 ATOM 4022 C CB . SER B 1 93 ? -21.858 32.689 -14.253 1.00 36.36 ? 91 SER B CB 1 ATOM 4023 O OG . SER B 1 93 ? -22.489 33.910 -13.904 1.00 43.16 ? 91 SER B OG 1 ATOM 4024 N N . CYS B 1 94 ? -22.060 32.624 -10.912 1.00 46.69 ? 92 CYS B N 1 ATOM 4025 C CA . CYS B 1 94 ? -21.568 33.264 -9.683 1.00 48.28 ? 92 CYS B CA 1 ATOM 4026 C C . CYS B 1 94 ? -20.740 34.505 -9.972 1.00 51.37 ? 92 CYS B C 1 ATOM 4027 O O . CYS B 1 94 ? -19.895 34.872 -9.170 1.00 52.81 ? 92 CYS B O 1 ATOM 4028 C CB . CYS B 1 94 ? -20.840 32.288 -8.762 1.00 49.99 ? 92 CYS B CB 1 ATOM 4029 S SG . CYS B 1 94 ? -21.915 31.005 -8.100 1.00 55.18 ? 92 CYS B SG 1 ATOM 4030 N N . SER B 1 95 ? -20.989 35.150 -11.122 1.00 46.36 ? 93 SER B N 1 ATOM 4031 C CA . SER B 1 95 ? -20.374 36.408 -11.575 1.00 45.42 ? 93 SER B CA 1 ATOM 4032 C C . SER B 1 95 ? -18.852 36.335 -11.732 1.00 49.97 ? 93 SER B C 1 ATOM 4033 O O . SER B 1 95 ? -18.186 37.375 -11.831 1.00 51.09 ? 93 SER B O 1 ATOM 4034 C CB . SER B 1 95 ? -20.785 37.581 -10.673 1.00 44.79 ? 93 SER B CB 1 ATOM 4035 O OG . SER B 1 95 ? -22.135 37.518 -10.235 1.00 38.30 ? 93 SER B OG 1 ATOM 4036 N N . LYS B 1 96 ? -18.305 35.114 -11.816 1.00 45.39 ? 94 LYS B N 1 ATOM 4037 C CA . LYS B 1 96 ? -16.860 34.905 -11.982 1.00 44.56 ? 94 LYS B CA 1 ATOM 4038 C C . LYS B 1 96 ? -16.652 33.942 -13.136 1.00 46.74 ? 94 LYS B C 1 ATOM 4039 O O . LYS B 1 96 ? -17.226 32.853 -13.151 1.00 47.33 ? 94 LYS B O 1 ATOM 4040 C CB . LYS B 1 96 ? -16.212 34.441 -10.651 1.00 47.65 ? 94 LYS B CB 1 ATOM 4041 C CG . LYS B 1 96 ? -14.712 34.085 -10.686 1.00 71.29 ? 94 LYS B CG 1 ATOM 4042 C CD . LYS B 1 96 ? -13.743 35.277 -10.825 1.00 80.71 ? 94 LYS B CD 1 ATOM 4043 C CE . LYS B 1 96 ? -12.331 34.788 -11.085 1.00 89.62 ? 94 LYS B CE 1 ATOM 4044 N NZ . LYS B 1 96 ? -11.401 35.899 -11.416 1.00 95.31 ? 94 LYS B NZ 1 ATOM 4045 N N . ASP B 1 97 ? -15.890 34.381 -14.137 1.00 41.88 ? 95 ASP B N 1 ATOM 4046 C CA . ASP B 1 97 ? -15.647 33.639 -15.365 1.00 41.60 ? 95 ASP B CA 1 ATOM 4047 C C . ASP B 1 97 ? -15.138 32.213 -15.162 1.00 45.99 ? 95 ASP B C 1 ATOM 4048 O O . ASP B 1 97 ? -15.592 31.300 -15.877 1.00 45.46 ? 95 ASP B O 1 ATOM 4049 C CB . ASP B 1 97 ? -14.712 34.423 -16.291 1.00 44.05 ? 95 ASP B CB 1 ATOM 4050 C CG . ASP B 1 97 ? -13.331 34.764 -15.751 1.00 49.41 ? 95 ASP B CG 1 ATOM 4051 O OD1 . ASP B 1 97 ? -13.124 34.653 -14.515 1.00 51.78 ? 95 ASP B OD1 1 ATOM 4052 O OD2 . ASP B 1 97 ? -12.474 35.181 -16.552 1.00 42.69 ? 95 ASP B OD2 1 ATOM 4053 N N . THR B 1 98 ? -14.230 32.008 -14.174 1.00 41.97 ? 96 THR B N 1 ATOM 4054 C CA . THR B 1 98 ? -13.662 30.681 -13.912 1.00 41.48 ? 96 THR B CA 1 ATOM 4055 C C . THR B 1 98 ? -14.719 29.725 -13.410 1.00 43.65 ? 96 THR B C 1 ATOM 4056 O O . THR B 1 98 ? -14.642 28.528 -13.693 1.00 43.66 ? 96 THR B O 1 ATOM 4057 C CB . THR B 1 98 ? -12.506 30.739 -12.902 1.00 53.66 ? 96 THR B CB 1 ATOM 4058 O OG1 . THR B 1 98 ? -12.989 31.297 -11.674 1.00 55.95 ? 96 THR B OG1 1 ATOM 4059 C CG2 . THR B 1 98 ? -11.276 31.480 -13.441 1.00 52.01 ? 96 THR B CG2 1 ATOM 4060 N N . HIS B 1 99 ? -15.685 30.252 -12.642 1.00 39.35 ? 97 HIS B N 1 ATOM 4061 C CA . HIS B 1 99 ? -16.769 29.475 -12.075 1.00 39.31 ? 97 HIS B CA 1 ATOM 4062 C C . HIS B 1 99 ? -17.699 29.090 -13.180 1.00 39.18 ? 97 HIS B C 1 ATOM 4063 O O . HIS B 1 99 ? -18.020 27.899 -13.314 1.00 35.77 ? 97 HIS B O 1 ATOM 4064 C CB . HIS B 1 99 ? -17.512 30.260 -10.987 1.00 41.22 ? 97 HIS B CB 1 ATOM 4065 C CG . HIS B 1 99 ? -18.479 29.406 -10.219 1.00 45.58 ? 97 HIS B CG 1 ATOM 4066 N ND1 . HIS B 1 99 ? -19.738 29.089 -10.732 1.00 48.11 ? 97 HIS B ND1 1 ATOM 4067 C CD2 . HIS B 1 99 ? -18.326 28.787 -9.027 1.00 46.88 ? 97 HIS B CD2 1 ATOM 4068 C CE1 . HIS B 1 99 ? -20.318 28.329 -9.809 1.00 47.24 ? 97 HIS B CE1 1 ATOM 4069 N NE2 . HIS B 1 99 ? -19.508 28.121 -8.769 1.00 47.07 ? 97 HIS B NE2 1 ATOM 4070 N N . ALA B 1 100 ? -18.058 30.090 -14.038 1.00 36.53 ? 98 ALA B N 1 ATOM 4071 C CA . ALA B 1 100 ? -18.917 29.867 -15.210 1.00 37.21 ? 98 ALA B CA 1 ATOM 4072 C C . ALA B 1 100 ? -18.418 28.648 -16.005 1.00 42.58 ? 98 ALA B C 1 ATOM 4073 O O . ALA B 1 100 ? -19.231 27.768 -16.296 1.00 40.77 ? 98 ALA B O 1 ATOM 4074 C CB . ALA B 1 100 ? -18.967 31.106 -16.084 1.00 37.61 ? 98 ALA B CB 1 ATOM 4075 N N . LEU B 1 101 ? -17.123 28.546 -16.224 1.00 40.67 ? 99 LEU B N 1 ATOM 4076 C CA . LEU B 1 101 ? -16.471 27.433 -16.888 1.00 42.20 ? 99 LEU B CA 1 ATOM 4077 C C . LEU B 1 101 ? -16.590 26.077 -16.212 1.00 48.83 ? 99 LEU B C 1 ATOM 4078 O O . LEU B 1 101 ? -16.805 25.081 -16.850 1.00 50.67 ? 99 LEU B O 1 ATOM 4079 C CB . LEU B 1 101 ? -15.008 27.782 -17.030 1.00 43.06 ? 99 LEU B CB 1 ATOM 4080 C CG . LEU B 1 101 ? -14.096 27.336 -18.158 1.00 48.78 ? 99 LEU B CG 1 ATOM 4081 C CD1 . LEU B 1 101 ? -14.791 27.250 -19.486 1.00 49.55 ? 99 LEU B CD1 1 ATOM 4082 C CD2 . LEU B 1 101 ? -12.954 28.309 -18.229 1.00 49.44 ? 99 LEU B CD2 1 ATOM 4083 N N . GLU B 1 102 ? -16.406 26.038 -14.914 1.00 45.01 ? 100 GLU B N 1 ATOM 4084 C CA . GLU B 1 102 ? -16.532 24.803 -14.143 1.00 43.88 ? 100 GLU B CA 1 ATOM 4085 C C . GLU B 1 102 ? -17.926 24.234 -14.352 1.00 47.95 ? 100 GLU B C 1 ATOM 4086 O O . GLU B 1 102 ? -18.102 23.025 -14.529 1.00 48.76 ? 100 GLU B O 1 ATOM 4087 C CB . GLU B 1 102 ? -16.302 25.075 -12.659 1.00 44.85 ? 100 GLU B CB 1 ATOM 4088 C CG . GLU B 1 102 ? -14.882 25.417 -12.269 1.00 52.06 ? 100 GLU B CG 1 ATOM 4089 C CD . GLU B 1 102 ? -14.720 26.056 -10.898 1.00 74.24 ? 100 GLU B CD 1 ATOM 4090 O OE1 . GLU B 1 102 ? -15.652 25.940 -10.064 1.00 65.43 ? 100 GLU B OE1 1 ATOM 4091 O OE2 . GLU B 1 102 ? -13.662 26.690 -10.666 1.00 56.08 ? 100 GLU B OE2 1 ATOM 4092 N N . GLN B 1 103 ? -18.914 25.123 -14.351 1.00 44.24 ? 101 GLN B N 1 ATOM 4093 C CA . GLN B 1 103 ? -20.320 24.789 -14.581 1.00 43.35 ? 101 GLN B CA 1 ATOM 4094 C C . GLN B 1 103 ? -20.519 24.410 -16.015 1.00 45.13 ? 101 GLN B C 1 ATOM 4095 O O . GLN B 1 103 ? -21.076 23.362 -16.283 1.00 45.27 ? 101 GLN B O 1 ATOM 4096 C CB . GLN B 1 103 ? -21.234 25.982 -14.223 1.00 44.33 ? 101 GLN B CB 1 ATOM 4097 C CG . GLN B 1 103 ? -21.264 26.351 -12.740 1.00 43.28 ? 101 GLN B CG 1 ATOM 4098 C CD . GLN B 1 103 ? -21.287 25.146 -11.865 1.00 46.64 ? 101 GLN B CD 1 ATOM 4099 O OE1 . GLN B 1 103 ? -22.252 24.366 -11.844 1.00 39.39 ? 101 GLN B OE1 1 ATOM 4100 N NE2 . GLN B 1 103 ? -20.158 24.918 -11.221 1.00 39.35 ? 101 GLN B NE2 1 ATOM 4101 N N . ALA B 1 104 ? -20.026 25.241 -16.937 1.00 40.61 ? 102 ALA B N 1 ATOM 4102 C CA . ALA B 1 104 ? -20.139 25.046 -18.371 1.00 39.40 ? 102 ALA B CA 1 ATOM 4103 C C . ALA B 1 104 ? -19.674 23.657 -18.836 1.00 39.10 ? 102 ALA B C 1 ATOM 4104 O O . ALA B 1 104 ? -20.191 23.179 -19.830 1.00 35.56 ? 102 ALA B O 1 ATOM 4105 C CB . ALA B 1 104 ? -19.443 26.164 -19.121 1.00 39.67 ? 102 ALA B CB 1 ATOM 4106 N N . LEU B 1 105 ? -18.847 22.941 -18.047 1.00 37.54 ? 103 LEU B N 1 ATOM 4107 C CA . LEU B 1 105 ? -18.484 21.547 -18.410 1.00 38.27 ? 103 LEU B CA 1 ATOM 4108 C C . LEU B 1 105 ? -19.697 20.659 -18.600 1.00 42.97 ? 103 LEU B C 1 ATOM 4109 O O . LEU B 1 105 ? -19.681 19.823 -19.485 1.00 42.82 ? 103 LEU B O 1 ATOM 4110 C CB . LEU B 1 105 ? -17.498 20.882 -17.443 1.00 37.88 ? 103 LEU B CB 1 ATOM 4111 C CG . LEU B 1 105 ? -16.018 21.087 -17.733 1.00 41.88 ? 103 LEU B CG 1 ATOM 4112 C CD1 . LEU B 1 105 ? -15.175 20.329 -16.732 1.00 41.22 ? 103 LEU B CD1 1 ATOM 4113 C CD2 . LEU B 1 105 ? -15.641 20.617 -19.149 1.00 45.26 ? 103 LEU B CD2 1 ATOM 4114 N N . ASP B 1 106 ? -20.767 20.876 -17.822 1.00 40.25 ? 104 ASP B N 1 ATOM 4115 C CA . ASP B 1 106 ? -22.042 20.150 -17.960 1.00 40.27 ? 104 ASP B CA 1 ATOM 4116 C C . ASP B 1 106 ? -22.535 20.116 -19.413 1.00 44.07 ? 104 ASP B C 1 ATOM 4117 O O . ASP B 1 106 ? -22.924 19.062 -19.905 1.00 44.56 ? 104 ASP B O 1 ATOM 4118 C CB . ASP B 1 106 ? -23.113 20.825 -17.103 1.00 41.99 ? 104 ASP B CB 1 ATOM 4119 C CG . ASP B 1 106 ? -23.034 20.466 -15.652 1.00 56.89 ? 104 ASP B CG 1 ATOM 4120 O OD1 . ASP B 1 106 ? -21.899 20.318 -15.137 1.00 59.82 ? 104 ASP B OD1 1 ATOM 4121 O OD2 . ASP B 1 106 ? -24.103 20.345 -15.019 1.00 64.73 ? 104 ASP B OD2 1 ATOM 4122 N N . PHE B 1 107 ? -22.498 21.270 -20.092 1.00 38.92 ? 105 PHE B N 1 ATOM 4123 C CA . PHE B 1 107 ? -22.916 21.448 -21.475 1.00 37.66 ? 105 PHE B CA 1 ATOM 4124 C C . PHE B 1 107 ? -22.197 20.551 -22.456 1.00 44.22 ? 105 PHE B C 1 ATOM 4125 O O . PHE B 1 107 ? -22.713 20.309 -23.547 1.00 45.79 ? 105 PHE B O 1 ATOM 4126 C CB . PHE B 1 107 ? -22.649 22.908 -21.891 1.00 38.11 ? 105 PHE B CB 1 ATOM 4127 C CG . PHE B 1 107 ? -23.445 23.958 -21.145 1.00 38.50 ? 105 PHE B CG 1 ATOM 4128 C CD1 . PHE B 1 107 ? -24.751 23.705 -20.732 1.00 39.34 ? 105 PHE B CD1 1 ATOM 4129 C CD2 . PHE B 1 107 ? -22.931 25.240 -20.958 1.00 38.36 ? 105 PHE B CD2 1 ATOM 4130 C CE1 . PHE B 1 107 ? -25.489 24.688 -20.082 1.00 39.53 ? 105 PHE B CE1 1 ATOM 4131 C CE2 . PHE B 1 107 ? -23.695 26.235 -20.355 1.00 39.05 ? 105 PHE B CE2 1 ATOM 4132 C CZ . PHE B 1 107 ? -24.964 25.956 -19.924 1.00 37.58 ? 105 PHE B CZ 1 ATOM 4133 N N . VAL B 1 108 ? -20.969 20.134 -22.120 1.00 41.65 ? 106 VAL B N 1 ATOM 4134 C CA . VAL B 1 108 ? -20.084 19.390 -23.019 1.00 41.73 ? 106 VAL B CA 1 ATOM 4135 C C . VAL B 1 108 ? -19.656 18.038 -22.487 1.00 50.61 ? 106 VAL B C 1 ATOM 4136 O O . VAL B 1 108 ? -18.922 17.330 -23.175 1.00 51.63 ? 106 VAL B O 1 ATOM 4137 C CB . VAL B 1 108 ? -18.839 20.253 -23.413 1.00 44.07 ? 106 VAL B CB 1 ATOM 4138 C CG1 . VAL B 1 108 ? -19.252 21.654 -23.850 1.00 43.01 ? 106 VAL B CG1 1 ATOM 4139 C CG2 . VAL B 1 108 ? -17.811 20.336 -22.276 1.00 43.79 ? 106 VAL B CG2 1 ATOM 4140 N N . ARG B 1 109 ? -20.058 17.691 -21.268 1.00 51.43 ? 107 ARG B N 1 ATOM 4141 C CA . ARG B 1 109 ? -19.603 16.461 -20.621 1.00 53.32 ? 107 ARG B CA 1 ATOM 4142 C C . ARG B 1 109 ? -19.908 15.175 -21.424 1.00 63.58 ? 107 ARG B C 1 ATOM 4143 O O . ARG B 1 109 ? -19.021 14.324 -21.564 1.00 64.04 ? 107 ARG B O 1 ATOM 4144 C CB . ARG B 1 109 ? -20.114 16.365 -19.187 1.00 49.69 ? 107 ARG B CB 1 ATOM 4145 C CG . ARG B 1 109 ? -19.035 15.807 -18.288 1.00 55.33 ? 107 ARG B CG 1 ATOM 4146 C CD . ARG B 1 109 ? -19.482 15.661 -16.856 1.00 53.67 ? 107 ARG B CD 1 ATOM 4147 N NE . ARG B 1 109 ? -18.649 16.458 -15.962 1.00 55.43 ? 107 ARG B NE 1 ATOM 4148 C CZ . ARG B 1 109 ? -19.022 17.617 -15.437 1.00 64.26 ? 107 ARG B CZ 1 ATOM 4149 N NH1 . ARG B 1 109 ? -18.209 18.272 -14.621 1.00 45.63 ? 107 ARG B NH1 1 ATOM 4150 N NH2 . ARG B 1 109 ? -20.223 18.119 -15.703 1.00 56.63 ? 107 ARG B NH2 1 ATOM 4151 N N . ALA B 1 110 ? -21.132 15.066 -21.975 1.00 62.74 ? 108 ALA B N 1 ATOM 4152 C CA . ALA B 1 110 ? -21.580 13.920 -22.763 1.00 63.72 ? 108 ALA B CA 1 ATOM 4153 C C . ALA B 1 110 ? -20.595 13.617 -23.882 1.00 68.64 ? 108 ALA B C 1 ATOM 4154 O O . ALA B 1 110 ? -20.012 12.539 -23.882 1.00 68.92 ? 108 ALA B O 1 ATOM 4155 C CB . ALA B 1 110 ? -22.978 14.175 -23.334 1.00 64.61 ? 108 ALA B CB 1 ATOM 4156 N N . SER B 1 111 ? -20.375 14.590 -24.785 1.00 65.94 ? 109 SER B N 1 ATOM 4157 C CA . SER B 1 111 ? -19.464 14.522 -25.922 1.00 66.51 ? 109 SER B CA 1 ATOM 4158 C C . SER B 1 111 ? -18.043 14.103 -25.509 1.00 70.69 ? 109 SER B C 1 ATOM 4159 O O . SER B 1 111 ? -17.508 13.162 -26.085 1.00 70.38 ? 109 SER B O 1 ATOM 4160 C CB . SER B 1 111 ? -19.446 15.860 -26.657 1.00 71.68 ? 109 SER B CB 1 ATOM 4161 O OG . SER B 1 111 ? -18.414 15.927 -27.630 1.00 84.80 ? 109 SER B OG 1 ATOM 4162 N N . LEU B 1 112 ? -17.479 14.749 -24.472 1.00 67.35 ? 110 LEU B N 1 ATOM 4163 C CA . LEU B 1 112 ? -16.147 14.492 -23.920 1.00 67.46 ? 110 LEU B CA 1 ATOM 4164 C C . LEU B 1 112 ? -16.008 13.058 -23.289 1.00 75.77 ? 110 LEU B C 1 ATOM 4165 O O . LEU B 1 112 ? -14.926 12.687 -22.801 1.00 76.80 ? 110 LEU B O 1 ATOM 4166 C CB . LEU B 1 112 ? -15.803 15.624 -22.918 1.00 66.91 ? 110 LEU B CB 1 ATOM 4167 C CG . LEU B 1 112 ? -14.328 15.880 -22.582 1.00 70.79 ? 110 LEU B CG 1 ATOM 4168 C CD1 . LEU B 1 112 ? -13.622 16.662 -23.667 1.00 70.17 ? 110 LEU B CD1 1 ATOM 4169 C CD2 . LEU B 1 112 ? -14.201 16.620 -21.278 1.00 73.88 ? 110 LEU B CD2 1 ATOM 4170 N N . SER B 1 113 ? -17.110 12.254 -23.348 1.00 72.95 ? 111 SER B N 1 ATOM 4171 C CA . SER B 1 113 ? -17.254 10.858 -22.900 1.00 81.47 ? 111 SER B CA 1 ATOM 4172 C C . SER B 1 113 ? -16.535 10.498 -21.590 1.00 123.92 ? 111 SER B C 1 ATOM 4173 O O . SER B 1 113 ? -17.070 10.720 -20.501 1.00 91.07 ? 111 SER B O 1 ATOM 4174 C CB . SER B 1 113 ? -16.890 9.891 -24.029 1.00 83.44 ? 111 SER B CB 1 ATOM 4175 O OG . SER B 1 113 ? -17.726 10.058 -25.168 1.00 86.28 ? 111 SER B OG 1 ATOM 4176 N N . PRO B 1 135 ? -25.761 15.862 -18.630 1.00 80.31 ? 133 PRO B N 1 ATOM 4177 C CA . PRO B 1 135 ? -26.779 16.168 -19.654 1.00 79.73 ? 133 PRO B CA 1 ATOM 4178 C C . PRO B 1 135 ? -26.448 15.451 -20.957 1.00 83.79 ? 133 PRO B C 1 ATOM 4179 O O . PRO B 1 135 ? -25.325 15.581 -21.471 1.00 83.32 ? 133 PRO B O 1 ATOM 4180 C CB . PRO B 1 135 ? -26.730 17.699 -19.795 1.00 81.12 ? 133 PRO B CB 1 ATOM 4181 C CG . PRO B 1 135 ? -25.757 18.184 -18.773 1.00 85.54 ? 133 PRO B CG 1 ATOM 4182 C CD . PRO B 1 135 ? -24.927 17.030 -18.302 1.00 81.50 ? 133 PRO B CD 1 ATOM 4183 N N . THR B 1 136 ? -27.422 14.668 -21.475 1.00 79.38 ? 134 THR B N 1 ATOM 4184 C CA . THR B 1 136 ? -27.255 13.863 -22.694 1.00 77.61 ? 134 THR B CA 1 ATOM 4185 C C . THR B 1 136 ? -26.916 14.727 -23.928 1.00 76.76 ? 134 THR B C 1 ATOM 4186 O O . THR B 1 136 ? -26.020 14.337 -24.679 1.00 77.52 ? 134 THR B O 1 ATOM 4187 C CB . THR B 1 136 ? -28.442 12.897 -22.939 1.00 83.92 ? 134 THR B CB 1 ATOM 4188 O OG1 . THR B 1 136 ? -28.316 12.327 -24.242 1.00 82.79 ? 134 THR B OG1 1 ATOM 4189 C CG2 . THR B 1 136 ? -29.811 13.564 -22.800 1.00 82.67 ? 134 THR B CG2 1 ATOM 4190 N N . ALA B 1 137 ? -27.600 15.884 -24.124 1.00 67.28 ? 135 ALA B N 1 ATOM 4191 C CA . ALA B 1 137 ? -27.375 16.764 -25.276 1.00 64.33 ? 135 ALA B CA 1 ATOM 4192 C C . ALA B 1 137 ? -27.867 18.195 -25.039 1.00 64.13 ? 135 ALA B C 1 ATOM 4193 O O . ALA B 1 137 ? -29.003 18.385 -24.606 1.00 64.49 ? 135 ALA B O 1 ATOM 4194 C CB . ALA B 1 137 ? -28.053 16.190 -26.508 1.00 64.67 ? 135 ALA B CB 1 ATOM 4195 N N . ILE B 1 138 ? -27.002 19.196 -25.308 1.00 55.60 ? 136 ILE B N 1 ATOM 4196 C CA . ILE B 1 138 ? -27.323 20.628 -25.196 1.00 52.45 ? 136 ILE B CA 1 ATOM 4197 C C . ILE B 1 138 ? -27.348 21.200 -26.618 1.00 52.97 ? 136 ILE B C 1 ATOM 4198 O O . ILE B 1 138 ? -26.320 21.243 -27.308 1.00 52.04 ? 136 ILE B O 1 ATOM 4199 C CB . ILE B 1 138 ? -26.397 21.414 -24.204 1.00 53.76 ? 136 ILE B CB 1 ATOM 4200 C CG1 . ILE B 1 138 ? -26.582 20.936 -22.748 1.00 53.32 ? 136 ILE B CG1 1 ATOM 4201 C CG2 . ILE B 1 138 ? -26.569 22.949 -24.324 1.00 52.92 ? 136 ILE B CG2 1 ATOM 4202 C CD1 . ILE B 1 138 ? -27.951 21.236 -22.109 1.00 55.00 ? 136 ILE B CD1 1 ATOM 4203 N N . THR B 1 139 ? -28.526 21.617 -27.050 1.00 47.29 ? 137 THR B N 1 ATOM 4204 C CA . THR B 1 139 ? -28.712 22.121 -28.400 1.00 46.79 ? 137 THR B CA 1 ATOM 4205 C C . THR B 1 139 ? -28.105 23.549 -28.597 1.00 49.48 ? 137 THR B C 1 ATOM 4206 O O . THR B 1 139 ? -27.745 23.904 -29.725 1.00 49.62 ? 137 THR B O 1 ATOM 4207 C CB . THR B 1 139 ? -30.201 21.979 -28.747 1.00 50.28 ? 137 THR B CB 1 ATOM 4208 O OG1 . THR B 1 139 ? -30.407 20.633 -29.196 1.00 51.38 ? 137 THR B OG1 1 ATOM 4209 C CG2 . THR B 1 139 ? -30.673 22.964 -29.806 1.00 44.02 ? 137 THR B CG2 1 ATOM 4210 N N . GLY B 1 140 ? -28.017 24.335 -27.529 1.00 42.84 ? 138 GLY B N 1 ATOM 4211 C CA . GLY B 1 140 ? -27.514 25.700 -27.621 1.00 41.26 ? 138 GLY B CA 1 ATOM 4212 C C . GLY B 1 140 ? -27.548 26.392 -26.284 1.00 41.75 ? 138 GLY B C 1 ATOM 4213 O O . GLY B 1 140 ? -28.323 26.003 -25.406 1.00 41.97 ? 138 GLY B O 1 ATOM 4214 N N . VAL B 1 141 ? -26.699 27.402 -26.116 1.00 34.83 ? 139 VAL B N 1 ATOM 4215 C CA . VAL B 1 141 ? -26.553 28.104 -24.841 1.00 33.74 ? 139 VAL B CA 1 ATOM 4216 C C . VAL B 1 141 ? -27.018 29.579 -24.901 1.00 37.39 ? 139 VAL B C 1 ATOM 4217 O O . VAL B 1 141 ? -26.516 30.387 -25.688 1.00 34.78 ? 139 VAL B O 1 ATOM 4218 C CB . VAL B 1 141 ? -25.099 27.957 -24.298 1.00 36.41 ? 139 VAL B CB 1 ATOM 4219 C CG1 . VAL B 1 141 ? -24.861 28.791 -23.029 1.00 35.04 ? 139 VAL B CG1 1 ATOM 4220 C CG2 . VAL B 1 141 ? -24.734 26.478 -24.082 1.00 35.94 ? 139 VAL B CG2 1 ATOM 4221 N N . ILE B 1 142 ? -27.980 29.903 -24.034 1.00 35.98 ? 140 ILE B N 1 ATOM 4222 C CA . ILE B 1 142 ? -28.515 31.244 -23.850 1.00 36.60 ? 140 ILE B CA 1 ATOM 4223 C C . ILE B 1 142 ? -27.755 31.708 -22.667 1.00 42.26 ? 140 ILE B C 1 ATOM 4224 O O . ILE B 1 142 ? -28.022 31.279 -21.542 1.00 43.87 ? 140 ILE B O 1 ATOM 4225 C CB . ILE B 1 142 ? -30.042 31.279 -23.540 1.00 39.40 ? 140 ILE B CB 1 ATOM 4226 C CG1 . ILE B 1 142 ? -30.884 30.730 -24.723 1.00 39.40 ? 140 ILE B CG1 1 ATOM 4227 C CG2 . ILE B 1 142 ? -30.488 32.709 -23.083 1.00 38.86 ? 140 ILE B CG2 1 ATOM 4228 C CD1 . ILE B 1 142 ? -30.527 31.293 -26.123 1.00 41.22 ? 140 ILE B CD1 1 ATOM 4229 N N . GLY B 1 143 ? -26.797 32.560 -22.900 1.00 37.45 ? 141 GLY B N 1 ATOM 4230 C CA . GLY B 1 143 ? -26.064 32.996 -21.754 1.00 37.56 ? 141 GLY B CA 1 ATOM 4231 C C . GLY B 1 143 ? -24.782 33.729 -21.961 1.00 43.91 ? 141 GLY B C 1 ATOM 4232 O O . GLY B 1 143 ? -24.179 33.766 -23.055 1.00 42.76 ? 141 GLY B O 1 ATOM 4233 N N . GLY B 1 144 ? -24.338 34.131 -20.790 1.00 40.64 ? 142 GLY B N 1 ATOM 4234 C CA . GLY B 1 144 ? -23.230 34.990 -20.542 1.00 41.07 ? 142 GLY B CA 1 ATOM 4235 C C . GLY B 1 144 ? -23.892 36.325 -20.281 1.00 45.87 ? 142 GLY B C 1 ATOM 4236 O O . GLY B 1 144 ? -24.684 36.817 -21.107 1.00 43.93 ? 142 GLY B O 1 ATOM 4237 N N . SER B 1 145 ? -23.651 36.849 -19.082 1.00 42.38 ? 143 SER B N 1 ATOM 4238 C CA . SER B 1 145 ? -24.091 38.176 -18.694 1.00 42.79 ? 143 SER B CA 1 ATOM 4239 C C . SER B 1 145 ? -22.863 39.075 -18.930 1.00 47.93 ? 143 SER B C 1 ATOM 4240 O O . SER B 1 145 ? -22.842 39.860 -19.866 1.00 47.10 ? 143 SER B O 1 ATOM 4241 C CB . SER B 1 145 ? -24.524 38.200 -17.225 1.00 44.42 ? 143 SER B CB 1 ATOM 4242 O OG . SER B 1 145 ? -25.935 38.235 -17.112 1.00 46.25 ? 143 SER B OG 1 ATOM 4243 N N . TYR B 1 146 ? -21.825 38.886 -18.110 1.00 46.74 ? 144 TYR B N 1 ATOM 4244 C CA . TYR B 1 146 ? -20.550 39.595 -18.141 1.00 47.67 ? 144 TYR B CA 1 ATOM 4245 C C . TYR B 1 146 ? -19.739 39.093 -19.327 1.00 45.82 ? 144 TYR B C 1 ATOM 4246 O O . TYR B 1 146 ? -19.559 37.872 -19.472 1.00 43.66 ? 144 TYR B O 1 ATOM 4247 C CB . TYR B 1 146 ? -19.753 39.296 -16.854 1.00 51.53 ? 144 TYR B CB 1 ATOM 4248 C CG . TYR B 1 146 ? -20.406 39.697 -15.550 1.00 57.99 ? 144 TYR B CG 1 ATOM 4249 C CD1 . TYR B 1 146 ? -21.404 38.913 -14.977 1.00 60.88 ? 144 TYR B CD1 1 ATOM 4250 C CD2 . TYR B 1 146 ? -19.935 40.783 -14.821 1.00 60.48 ? 144 TYR B CD2 1 ATOM 4251 C CE1 . TYR B 1 146 ? -21.974 39.249 -13.751 1.00 63.41 ? 144 TYR B CE1 1 ATOM 4252 C CE2 . TYR B 1 146 ? -20.478 41.112 -13.582 1.00 62.41 ? 144 TYR B CE2 1 ATOM 4253 C CZ . TYR B 1 146 ? -21.511 40.353 -13.056 1.00 75.41 ? 144 TYR B CZ 1 ATOM 4254 O OH . TYR B 1 146 ? -22.060 40.687 -11.832 1.00 81.79 ? 144 TYR B OH 1 ATOM 4255 N N . SER B 1 147 ? -19.196 40.032 -20.122 1.00 39.94 ? 145 SER B N 1 ATOM 4256 C CA . SER B 1 147 ? -18.377 39.764 -21.314 1.00 39.86 ? 145 SER B CA 1 ATOM 4257 C C . SER B 1 147 ? -17.305 38.701 -21.060 1.00 45.45 ? 145 SER B C 1 ATOM 4258 O O . SER B 1 147 ? -17.172 37.794 -21.871 1.00 42.55 ? 145 SER B O 1 ATOM 4259 C CB . SER B 1 147 ? -17.713 41.045 -21.804 1.00 42.51 ? 145 SER B CB 1 ATOM 4260 O OG . SER B 1 147 ? -18.612 41.956 -22.416 1.00 48.30 ? 145 SER B OG 1 ATOM 4261 N N . ASP B 1 148 ? -16.581 38.796 -19.902 1.00 45.60 ? 146 ASP B N 1 ATOM 4262 C CA . ASP B 1 148 ? -15.513 37.892 -19.490 1.00 46.63 ? 146 ASP B CA 1 ATOM 4263 C C . ASP B 1 148 ? -15.986 36.439 -19.358 1.00 49.68 ? 146 ASP B C 1 ATOM 4264 O O . ASP B 1 148 ? -15.268 35.512 -19.754 1.00 48.78 ? 146 ASP B O 1 ATOM 4265 C CB . ASP B 1 148 ? -14.817 38.402 -18.218 1.00 50.35 ? 146 ASP B CB 1 ATOM 4266 C CG . ASP B 1 148 ? -13.456 39.105 -18.437 1.00 73.07 ? 146 ASP B CG 1 ATOM 4267 O OD1 . ASP B 1 148 ? -12.905 39.024 -19.581 1.00 73.45 ? 146 ASP B OD1 1 ATOM 4268 O OD2 . ASP B 1 148 ? -12.919 39.696 -17.454 1.00 79.02 ? 146 ASP B OD2 1 ATOM 4269 N N . VAL B 1 149 ? -17.230 36.263 -18.888 1.00 44.79 ? 147 VAL B N 1 ATOM 4270 C CA . VAL B 1 149 ? -17.916 34.979 -18.753 1.00 42.95 ? 147 VAL B CA 1 ATOM 4271 C C . VAL B 1 149 ? -18.235 34.424 -20.168 1.00 46.54 ? 147 VAL B C 1 ATOM 4272 O O . VAL B 1 149 ? -17.916 33.262 -20.465 1.00 46.80 ? 147 VAL B O 1 ATOM 4273 C CB . VAL B 1 149 ? -19.193 35.160 -17.884 1.00 44.93 ? 147 VAL B CB 1 ATOM 4274 C CG1 . VAL B 1 149 ? -20.144 33.988 -18.032 1.00 44.25 ? 147 VAL B CG1 1 ATOM 4275 C CG2 . VAL B 1 149 ? -18.832 35.384 -16.417 1.00 44.25 ? 147 VAL B CG2 1 ATOM 4276 N N . SER B 1 150 ? -18.852 35.257 -21.027 1.00 41.18 ? 148 SER B N 1 ATOM 4277 C CA . SER B 1 150 ? -19.232 34.873 -22.385 1.00 41.02 ? 148 SER B CA 1 ATOM 4278 C C . SER B 1 150 ? -18.042 34.488 -23.219 1.00 47.01 ? 148 SER B C 1 ATOM 4279 O O . SER B 1 150 ? -18.166 33.550 -24.015 1.00 48.17 ? 148 SER B O 1 ATOM 4280 C CB . SER B 1 150 ? -20.044 35.965 -23.083 1.00 42.18 ? 148 SER B CB 1 ATOM 4281 O OG . SER B 1 150 ? -21.259 36.190 -22.387 1.00 43.79 ? 148 SER B OG 1 ATOM 4282 N N . ILE B 1 151 ? -16.894 35.195 -23.030 1.00 42.15 ? 149 ILE B N 1 ATOM 4283 C CA . ILE B 1 151 ? -15.635 34.938 -23.724 1.00 41.89 ? 149 ILE B CA 1 ATOM 4284 C C . ILE B 1 151 ? -15.054 33.562 -23.265 1.00 46.00 ? 149 ILE B C 1 ATOM 4285 O O . ILE B 1 151 ? -14.731 32.729 -24.101 1.00 46.63 ? 149 ILE B O 1 ATOM 4286 C CB . ILE B 1 151 ? -14.649 36.131 -23.554 1.00 44.97 ? 149 ILE B CB 1 ATOM 4287 C CG1 . ILE B 1 151 ? -15.114 37.348 -24.409 1.00 45.33 ? 149 ILE B CG1 1 ATOM 4288 C CG2 . ILE B 1 151 ? -13.224 35.728 -23.939 1.00 44.80 ? 149 ILE B CG2 1 ATOM 4289 C CD1 . ILE B 1 151 ? -14.658 38.793 -23.956 1.00 43.65 ? 149 ILE B CD1 1 ATOM 4290 N N . GLN B 1 152 ? -14.967 33.339 -21.955 1.00 40.92 ? 150 GLN B N 1 ATOM 4291 C CA . GLN B 1 152 ? -14.487 32.112 -21.335 1.00 40.74 ? 150 GLN B CA 1 ATOM 4292 C C . GLN B 1 152 ? -15.302 30.888 -21.773 1.00 43.36 ? 150 GLN B C 1 ATOM 4293 O O . GLN B 1 152 ? -14.731 29.875 -22.179 1.00 41.64 ? 150 GLN B O 1 ATOM 4294 C CB . GLN B 1 152 ? -14.593 32.260 -19.808 1.00 42.53 ? 150 GLN B CB 1 ATOM 4295 C CG . GLN B 1 152 ? -13.704 31.310 -19.012 1.00 67.62 ? 150 GLN B CG 1 ATOM 4296 C CD . GLN B 1 152 ? -12.414 31.941 -18.578 1.00 84.55 ? 150 GLN B CD 1 ATOM 4297 O OE1 . GLN B 1 152 ? -11.557 32.284 -19.397 1.00 79.10 ? 150 GLN B OE1 1 ATOM 4298 N NE2 . GLN B 1 152 ? -12.253 32.105 -17.273 1.00 76.99 ? 150 GLN B NE2 1 ATOM 4299 N N . VAL B 1 153 ? -16.646 30.998 -21.677 1.00 39.87 ? 151 VAL B N 1 ATOM 4300 C CA . VAL B 1 153 ? -17.599 29.941 -22.021 1.00 37.36 ? 151 VAL B CA 1 ATOM 4301 C C . VAL B 1 153 ? -17.610 29.709 -23.540 1.00 40.61 ? 151 VAL B C 1 ATOM 4302 O O . VAL B 1 153 ? -17.678 28.560 -23.979 1.00 41.32 ? 151 VAL B O 1 ATOM 4303 C CB . VAL B 1 153 ? -18.984 30.236 -21.390 1.00 38.77 ? 151 VAL B CB 1 ATOM 4304 C CG1 . VAL B 1 153 ? -20.071 29.268 -21.883 1.00 37.71 ? 151 VAL B CG1 1 ATOM 4305 C CG2 . VAL B 1 153 ? -18.886 30.203 -19.872 1.00 37.75 ? 151 VAL B CG2 1 ATOM 4306 N N . ALA B 1 154 ? -17.471 30.778 -24.332 1.00 36.84 ? 152 ALA B N 1 ATOM 4307 C CA . ALA B 1 154 ? -17.387 30.656 -25.797 1.00 37.16 ? 152 ALA B CA 1 ATOM 4308 C C . ALA B 1 154 ? -16.206 29.786 -26.216 1.00 41.21 ? 152 ALA B C 1 ATOM 4309 O O . ALA B 1 154 ? -16.370 28.956 -27.103 1.00 41.35 ? 152 ALA B O 1 ATOM 4310 C CB . ALA B 1 154 ? -17.224 32.025 -26.425 1.00 37.96 ? 152 ALA B CB 1 ATOM 4311 N N . ASN B 1 155 ? -15.017 29.971 -25.562 1.00 36.74 ? 153 ASN B N 1 ATOM 4312 C CA . ASN B 1 155 ? -13.771 29.267 -25.856 1.00 36.09 ? 153 ASN B CA 1 ATOM 4313 C C . ASN B 1 155 ? -13.876 27.775 -25.659 1.00 41.39 ? 153 ASN B C 1 ATOM 4314 O O . ASN B 1 155 ? -13.150 27.030 -26.299 1.00 42.38 ? 153 ASN B O 1 ATOM 4315 C CB . ASN B 1 155 ? -12.601 29.862 -25.091 1.00 37.08 ? 153 ASN B CB 1 ATOM 4316 C CG . ASN B 1 155 ? -12.211 31.229 -25.618 1.00 54.04 ? 153 ASN B CG 1 ATOM 4317 O OD1 . ASN B 1 155 ? -12.613 31.629 -26.711 1.00 38.70 ? 153 ASN B OD1 1 ATOM 4318 N ND2 . ASN B 1 155 ? -11.479 32.013 -24.830 1.00 46.39 ? 153 ASN B ND2 1 ATOM 4319 N N . LEU B 1 156 ? -14.831 27.335 -24.853 1.00 37.83 ? 154 LEU B N 1 ATOM 4320 C CA . LEU B 1 156 ? -15.082 25.923 -24.614 1.00 36.58 ? 154 LEU B CA 1 ATOM 4321 C C . LEU B 1 156 ? -16.214 25.433 -25.514 1.00 40.08 ? 154 LEU B C 1 ATOM 4322 O O . LEU B 1 156 ? -16.098 24.369 -26.119 1.00 39.19 ? 154 LEU B O 1 ATOM 4323 C CB . LEU B 1 156 ? -15.403 25.689 -23.113 1.00 35.38 ? 154 LEU B CB 1 ATOM 4324 C CG . LEU B 1 156 ? -15.840 24.276 -22.744 1.00 38.05 ? 154 LEU B CG 1 ATOM 4325 C CD1 . LEU B 1 156 ? -14.655 23.370 -22.580 1.00 37.79 ? 154 LEU B CD1 1 ATOM 4326 C CD2 . LEU B 1 156 ? -16.723 24.283 -21.509 1.00 38.46 ? 154 LEU B CD2 1 ATOM 4327 N N . LEU B 1 157 ? -17.260 26.208 -25.643 1.00 36.64 ? 155 LEU B N 1 ATOM 4328 C CA . LEU B 1 157 ? -18.405 25.791 -26.395 1.00 37.00 ? 155 LEU B CA 1 ATOM 4329 C C . LEU B 1 157 ? -18.131 25.616 -27.865 1.00 43.93 ? 155 LEU B C 1 ATOM 4330 O O . LEU B 1 157 ? -18.688 24.762 -28.465 1.00 45.79 ? 155 LEU B O 1 ATOM 4331 C CB . LEU B 1 157 ? -19.544 26.758 -26.195 1.00 36.46 ? 155 LEU B CB 1 ATOM 4332 C CG . LEU B 1 157 ? -20.236 26.812 -24.859 1.00 39.06 ? 155 LEU B CG 1 ATOM 4333 C CD1 . LEU B 1 157 ? -21.359 27.800 -24.911 1.00 38.65 ? 155 LEU B CD1 1 ATOM 4334 C CD2 . LEU B 1 157 ? -20.777 25.476 -24.490 1.00 38.70 ? 155 LEU B CD2 1 ATOM 4335 N N . ARG B 1 158 ? -17.259 26.430 -28.426 1.00 39.65 ? 156 ARG B N 1 ATOM 4336 C CA . ARG B 1 158 ? -16.821 26.337 -29.821 1.00 38.73 ? 156 ARG B CA 1 ATOM 4337 C C . ARG B 1 158 ? -16.090 25.014 -30.142 1.00 43.63 ? 156 ARG B C 1 ATOM 4338 O O . ARG B 1 158 ? -16.137 24.584 -31.295 1.00 44.87 ? 156 ARG B O 1 ATOM 4339 C CB . ARG B 1 158 ? -15.955 27.543 -30.212 1.00 36.67 ? 156 ARG B CB 1 ATOM 4340 C CG . ARG B 1 158 ? -14.517 27.509 -29.650 1.00 37.48 ? 156 ARG B CG 1 ATOM 4341 C CD . ARG B 1 158 ? -13.590 28.389 -30.462 1.00 42.23 ? 156 ARG B CD 1 ATOM 4342 N NE . ARG B 1 158 ? -13.429 27.887 -31.824 1.00 46.50 ? 156 ARG B NE 1 ATOM 4343 C CZ . ARG B 1 158 ? -12.425 27.111 -32.240 1.00 62.72 ? 156 ARG B CZ 1 ATOM 4344 N NH1 . ARG B 1 158 ? -11.452 26.758 -31.404 1.00 45.84 ? 156 ARG B NH1 1 ATOM 4345 N NH2 . ARG B 1 158 ? -12.378 26.695 -33.499 1.00 47.51 ? 156 ARG B NH2 1 ATOM 4346 N N . LEU B 1 159 ? -15.406 24.382 -29.143 1.00 38.18 ? 157 LEU B N 1 ATOM 4347 C CA . LEU B 1 159 ? -14.700 23.101 -29.295 1.00 37.18 ? 157 LEU B CA 1 ATOM 4348 C C . LEU B 1 159 ? -15.692 21.951 -29.490 1.00 41.73 ? 157 LEU B C 1 ATOM 4349 O O . LEU B 1 159 ? -15.269 20.840 -29.781 1.00 41.68 ? 157 LEU B O 1 ATOM 4350 C CB . LEU B 1 159 ? -13.873 22.759 -28.038 1.00 37.19 ? 157 LEU B CB 1 ATOM 4351 C CG . LEU B 1 159 ? -12.874 23.753 -27.469 1.00 40.86 ? 157 LEU B CG 1 ATOM 4352 C CD1 . LEU B 1 159 ? -12.441 23.314 -26.091 1.00 41.20 ? 157 LEU B CD1 1 ATOM 4353 C CD2 . LEU B 1 159 ? -11.685 23.919 -28.378 1.00 40.66 ? 157 LEU B CD2 1 ATOM 4354 N N . PHE B 1 160 ? -16.992 22.193 -29.214 1.00 38.81 ? 158 PHE B N 1 ATOM 4355 C CA . PHE B 1 160 ? -18.067 21.200 -29.291 1.00 37.39 ? 158 PHE B CA 1 ATOM 4356 C C . PHE B 1 160 ? -19.181 21.596 -30.272 1.00 43.65 ? 158 PHE B C 1 ATOM 4357 O O . PHE B 1 160 ? -20.199 20.910 -30.369 1.00 43.49 ? 158 PHE B O 1 ATOM 4358 C CB . PHE B 1 160 ? -18.608 20.901 -27.889 1.00 37.31 ? 158 PHE B CB 1 ATOM 4359 C CG . PHE B 1 160 ? -17.526 20.350 -26.995 1.00 37.94 ? 158 PHE B CG 1 ATOM 4360 C CD1 . PHE B 1 160 ? -16.709 21.203 -26.252 1.00 39.51 ? 158 PHE B CD1 1 ATOM 4361 C CD2 . PHE B 1 160 ? -17.283 18.982 -26.932 1.00 39.01 ? 158 PHE B CD2 1 ATOM 4362 C CE1 . PHE B 1 160 ? -15.698 20.697 -25.447 1.00 39.61 ? 158 PHE B CE1 1 ATOM 4363 C CE2 . PHE B 1 160 ? -16.240 18.476 -26.147 1.00 40.60 ? 158 PHE B CE2 1 ATOM 4364 C CZ . PHE B 1 160 ? -15.458 19.334 -25.417 1.00 38.71 ? 158 PHE B CZ 1 ATOM 4365 N N . GLN B 1 161 ? -18.958 22.680 -31.028 1.00 41.18 ? 159 GLN B N 1 ATOM 4366 C CA . GLN B 1 161 ? -19.904 23.193 -32.019 1.00 42.19 ? 159 GLN B CA 1 ATOM 4367 C C . GLN B 1 161 ? -21.263 23.573 -31.374 1.00 45.46 ? 159 GLN B C 1 ATOM 4368 O O . GLN B 1 161 ? -22.300 23.435 -32.013 1.00 44.88 ? 159 GLN B O 1 ATOM 4369 C CB . GLN B 1 161 ? -20.078 22.236 -33.237 1.00 43.99 ? 159 GLN B CB 1 ATOM 4370 C CG . GLN B 1 161 ? -18.822 21.959 -34.063 1.00 52.96 ? 159 GLN B CG 1 ATOM 4371 C CD . GLN B 1 161 ? -17.926 20.894 -33.453 1.00 75.28 ? 159 GLN B CD 1 ATOM 4372 O OE1 . GLN B 1 161 ? -18.359 19.774 -33.113 1.00 68.66 ? 159 GLN B OE1 1 ATOM 4373 N NE2 . GLN B 1 161 ? -16.647 21.233 -33.283 1.00 66.99 ? 159 GLN B NE2 1 ATOM 4374 N N . ILE B 1 162 ? -21.247 24.034 -30.095 1.00 40.13 ? 160 ILE B N 1 ATOM 4375 C CA . ILE B 1 162 ? -22.461 24.448 -29.418 1.00 38.50 ? 160 ILE B CA 1 ATOM 4376 C C . ILE B 1 162 ? -22.719 25.943 -29.642 1.00 41.23 ? 160 ILE B C 1 ATOM 4377 O O . ILE B 1 162 ? -21.948 26.783 -29.157 1.00 39.87 ? 160 ILE B O 1 ATOM 4378 C CB . ILE B 1 162 ? -22.497 24.058 -27.919 1.00 40.98 ? 160 ILE B CB 1 ATOM 4379 C CG1 . ILE B 1 162 ? -22.328 22.533 -27.729 1.00 41.06 ? 160 ILE B CG1 1 ATOM 4380 C CG2 . ILE B 1 162 ? -23.798 24.566 -27.265 1.00 39.28 ? 160 ILE B CG2 1 ATOM 4381 C CD1 . ILE B 1 162 ? -21.883 22.147 -26.366 1.00 43.89 ? 160 ILE B CD1 1 ATOM 4382 N N . PRO B 1 163 ? -23.816 26.284 -30.360 1.00 37.52 ? 161 PRO B N 1 ATOM 4383 C CA . PRO B 1 163 ? -24.173 27.718 -30.540 1.00 37.08 ? 161 PRO B CA 1 ATOM 4384 C C . PRO B 1 163 ? -24.474 28.448 -29.218 1.00 39.48 ? 161 PRO B C 1 ATOM 4385 O O . PRO B 1 163 ? -25.026 27.863 -28.275 1.00 39.38 ? 161 PRO B O 1 ATOM 4386 C CB . PRO B 1 163 ? -25.417 27.674 -31.436 1.00 38.35 ? 161 PRO B CB 1 ATOM 4387 C CG . PRO B 1 163 ? -25.464 26.266 -31.992 1.00 41.79 ? 161 PRO B CG 1 ATOM 4388 C CD . PRO B 1 163 ? -24.821 25.392 -30.975 1.00 37.44 ? 161 PRO B CD 1 ATOM 4389 N N . GLN B 1 164 ? -24.092 29.724 -29.148 1.00 33.82 ? 162 GLN B N 1 ATOM 4390 C CA . GLN B 1 164 ? -24.280 30.561 -27.962 1.00 32.42 ? 162 GLN B CA 1 ATOM 4391 C C . GLN B 1 164 ? -24.855 31.959 -28.302 1.00 36.69 ? 162 GLN B C 1 ATOM 4392 O O . GLN B 1 164 ? -24.412 32.606 -29.260 1.00 34.71 ? 162 GLN B O 1 ATOM 4393 C CB . GLN B 1 164 ? -22.957 30.674 -27.220 1.00 32.96 ? 162 GLN B CB 1 ATOM 4394 C CG . GLN B 1 164 ? -22.942 31.593 -26.011 1.00 40.75 ? 162 GLN B CG 1 ATOM 4395 C CD . GLN B 1 164 ? -21.564 31.671 -25.444 1.00 41.05 ? 162 GLN B CD 1 ATOM 4396 O OE1 . GLN B 1 164 ? -20.676 30.956 -25.872 1.00 37.90 ? 162 GLN B OE1 1 ATOM 4397 N NE2 . GLN B 1 164 ? -21.350 32.515 -24.454 1.00 33.82 ? 162 GLN B NE2 1 ATOM 4398 N N . ILE B 1 165 ? -25.884 32.388 -27.529 1.00 34.58 ? 163 ILE B N 1 ATOM 4399 C CA . ILE B 1 165 ? -26.514 33.693 -27.689 1.00 34.52 ? 163 ILE B CA 1 ATOM 4400 C C . ILE B 1 165 ? -26.465 34.463 -26.355 1.00 38.94 ? 163 ILE B C 1 ATOM 4401 O O . ILE B 1 165 ? -27.046 34.023 -25.380 1.00 39.57 ? 163 ILE B O 1 ATOM 4402 C CB . ILE B 1 165 ? -27.939 33.681 -28.354 1.00 37.02 ? 163 ILE B CB 1 ATOM 4403 C CG1 . ILE B 1 165 ? -28.039 32.654 -29.495 1.00 36.67 ? 163 ILE B CG1 1 ATOM 4404 C CG2 . ILE B 1 165 ? -28.357 35.121 -28.827 1.00 36.46 ? 163 ILE B CG2 1 ATOM 4405 C CD1 . ILE B 1 165 ? -29.403 32.503 -30.093 1.00 48.99 ? 163 ILE B CD1 1 ATOM 4406 N N . SER B 1 166 ? -25.750 35.584 -26.311 1.00 35.67 ? 164 SER B N 1 ATOM 4407 C CA . SER B 1 166 ? -25.708 36.374 -25.090 1.00 36.21 ? 164 SER B CA 1 ATOM 4408 C C . SER B 1 166 ? -26.770 37.455 -25.146 1.00 39.41 ? 164 SER B C 1 ATOM 4409 O O . SER B 1 166 ? -27.030 38.007 -26.213 1.00 39.23 ? 164 SER B O 1 ATOM 4410 C CB . SER B 1 166 ? -24.332 36.995 -24.829 1.00 39.00 ? 164 SER B CB 1 ATOM 4411 O OG . SER B 1 166 ? -24.357 37.677 -23.578 1.00 39.98 ? 164 SER B OG 1 ATOM 4412 N N . TYR B 1 167 ? -27.318 37.790 -23.969 1.00 33.43 ? 165 TYR B N 1 ATOM 4413 C CA . TYR B 1 167 ? -28.378 38.765 -23.765 1.00 32.20 ? 165 TYR B CA 1 ATOM 4414 C C . TYR B 1 167 ? -27.843 40.048 -23.111 1.00 36.24 ? 165 TYR B C 1 ATOM 4415 O O . TYR B 1 167 ? -28.599 40.996 -22.902 1.00 33.10 ? 165 TYR B O 1 ATOM 4416 C CB . TYR B 1 167 ? -29.480 38.113 -22.894 1.00 31.37 ? 165 TYR B CB 1 ATOM 4417 C CG . TYR B 1 167 ? -28.925 37.445 -21.659 1.00 30.58 ? 165 TYR B CG 1 ATOM 4418 C CD1 . TYR B 1 167 ? -28.517 38.199 -20.559 1.00 31.57 ? 165 TYR B CD1 1 ATOM 4419 C CD2 . TYR B 1 167 ? -28.751 36.060 -21.604 1.00 30.55 ? 165 TYR B CD2 1 ATOM 4420 C CE1 . TYR B 1 167 ? -27.943 37.598 -19.440 1.00 29.44 ? 165 TYR B CE1 1 ATOM 4421 C CE2 . TYR B 1 167 ? -28.213 35.442 -20.464 1.00 30.03 ? 165 TYR B CE2 1 ATOM 4422 C CZ . TYR B 1 167 ? -27.788 36.223 -19.399 1.00 32.09 ? 165 TYR B CZ 1 ATOM 4423 O OH . TYR B 1 167 ? -27.210 35.681 -18.282 1.00 35.83 ? 165 TYR B OH 1 ATOM 4424 N N . ALA B 1 168 ? -26.526 40.072 -22.796 1.00 35.79 ? 166 ALA B N 1 ATOM 4425 C CA . ALA B 1 168 ? -25.921 41.164 -22.045 1.00 35.69 ? 166 ALA B CA 1 ATOM 4426 C C . ALA B 1 168 ? -24.491 41.510 -22.365 1.00 44.74 ? 166 ALA B C 1 ATOM 4427 O O . ALA B 1 168 ? -24.069 42.614 -22.013 1.00 47.38 ? 166 ALA B O 1 ATOM 4428 C CB . ALA B 1 168 ? -26.007 40.833 -20.573 1.00 36.07 ? 166 ALA B CB 1 ATOM 4429 N N . SER B 1 169 ? -23.697 40.561 -22.905 1.00 41.96 ? 167 SER B N 1 ATOM 4430 C CA . SER B 1 169 ? -22.266 40.789 -23.184 1.00 40.99 ? 167 SER B CA 1 ATOM 4431 C C . SER B 1 169 ? -22.031 41.732 -24.360 1.00 44.64 ? 167 SER B C 1 ATOM 4432 O O . SER B 1 169 ? -22.494 41.478 -25.474 1.00 44.48 ? 167 SER B O 1 ATOM 4433 C CB . SER B 1 169 ? -21.536 39.469 -23.371 1.00 41.95 ? 167 SER B CB 1 ATOM 4434 O OG . SER B 1 169 ? -21.536 38.782 -22.134 1.00 47.59 ? 167 SER B OG 1 ATOM 4435 N N . THR B 1 170 ? -21.313 42.821 -24.109 1.00 39.82 ? 168 THR B N 1 ATOM 4436 C CA . THR B 1 170 ? -21.113 43.830 -25.144 1.00 39.40 ? 168 THR B CA 1 ATOM 4437 C C . THR B 1 170 ? -19.653 44.118 -25.526 1.00 44.88 ? 168 THR B C 1 ATOM 4438 O O . THR B 1 170 ? -19.455 45.035 -26.320 1.00 47.14 ? 168 THR B O 1 ATOM 4439 C CB . THR B 1 170 ? -21.824 45.143 -24.764 1.00 37.95 ? 168 THR B CB 1 ATOM 4440 O OG1 . THR B 1 170 ? -21.424 45.524 -23.440 1.00 42.07 ? 168 THR B OG1 1 ATOM 4441 C CG2 . THR B 1 170 ? -23.335 45.060 -24.880 1.00 25.23 ? 168 THR B CG2 1 ATOM 4442 N N . SER B 1 171 ? -18.651 43.335 -25.066 1.00 39.31 ? 169 SER B N 1 ATOM 4443 C CA . SER B 1 171 ? -17.263 43.584 -25.482 1.00 39.43 ? 169 SER B CA 1 ATOM 4444 C C . SER B 1 171 ? -17.122 43.511 -27.020 1.00 47.64 ? 169 SER B C 1 ATOM 4445 O O . SER B 1 171 ? -17.823 42.735 -27.679 1.00 47.52 ? 169 SER B O 1 ATOM 4446 C CB . SER B 1 171 ? -16.307 42.608 -24.813 1.00 42.03 ? 169 SER B CB 1 ATOM 4447 O OG . SER B 1 171 ? -14.974 42.922 -25.171 1.00 53.72 ? 169 SER B OG 1 ATOM 4448 N N . ALA B 1 172 ? -16.279 44.376 -27.598 1.00 46.34 ? 170 ALA B N 1 ATOM 4449 C CA . ALA B 1 172 ? -16.110 44.416 -29.058 1.00 45.61 ? 170 ALA B CA 1 ATOM 4450 C C . ALA B 1 172 ? -15.413 43.169 -29.583 1.00 48.65 ? 170 ALA B C 1 ATOM 4451 O O . ALA B 1 172 ? -15.741 42.734 -30.675 1.00 47.89 ? 170 ALA B O 1 ATOM 4452 C CB . ALA B 1 172 ? -15.367 45.665 -29.482 1.00 45.82 ? 170 ALA B CB 1 ATOM 4453 N N . LYS B 1 173 ? -14.496 42.574 -28.784 1.00 45.40 ? 171 LYS B N 1 ATOM 4454 C CA . LYS B 1 173 ? -13.759 41.332 -29.083 1.00 45.16 ? 171 LYS B CA 1 ATOM 4455 C C . LYS B 1 173 ? -14.704 40.258 -29.670 1.00 45.07 ? 171 LYS B C 1 ATOM 4456 O O . LYS B 1 173 ? -14.409 39.684 -30.711 1.00 43.90 ? 171 LYS B O 1 ATOM 4457 C CB . LYS B 1 173 ? -13.146 40.733 -27.788 1.00 48.30 ? 171 LYS B CB 1 ATOM 4458 C CG . LYS B 1 173 ? -12.031 41.503 -27.123 1.00 68.38 ? 171 LYS B CG 1 ATOM 4459 C CD . LYS B 1 173 ? -11.184 40.480 -26.379 1.00 80.19 ? 171 LYS B CD 1 ATOM 4460 C CE . LYS B 1 173 ? -9.843 40.991 -25.937 1.00 92.61 ? 171 LYS B CE 1 ATOM 4461 N NZ . LYS B 1 173 ? -9.078 39.920 -25.243 1.00 108.69 ? 171 LYS B NZ 1 ATOM 4462 N N . LEU B 1 174 ? -15.844 40.011 -28.992 1.00 38.61 ? 172 LEU B N 1 ATOM 4463 C CA . LEU B 1 174 ? -16.837 39.020 -29.370 1.00 38.05 ? 172 LEU B CA 1 ATOM 4464 C C . LEU B 1 174 ? -17.353 39.140 -30.813 1.00 42.26 ? 172 LEU B C 1 ATOM 4465 O O . LEU B 1 174 ? -17.823 38.156 -31.378 1.00 43.95 ? 172 LEU B O 1 ATOM 4466 C CB . LEU B 1 174 ? -17.979 39.035 -28.362 1.00 38.11 ? 172 LEU B CB 1 ATOM 4467 C CG . LEU B 1 174 ? -17.614 38.457 -26.979 1.00 41.62 ? 172 LEU B CG 1 ATOM 4468 C CD1 . LEU B 1 174 ? -18.579 38.960 -25.878 1.00 39.86 ? 172 LEU B CD1 1 ATOM 4469 C CD2 . LEU B 1 174 ? -17.495 36.913 -27.041 1.00 42.41 ? 172 LEU B CD2 1 ATOM 4470 N N . SER B 1 175 ? -17.189 40.291 -31.434 1.00 37.51 ? 173 SER B N 1 ATOM 4471 C CA . SER B 1 175 ? -17.574 40.496 -32.823 1.00 38.17 ? 173 SER B CA 1 ATOM 4472 C C . SER B 1 175 ? -16.663 39.736 -33.845 1.00 41.76 ? 173 SER B C 1 ATOM 4473 O O . SER B 1 175 ? -17.067 39.547 -35.006 1.00 39.59 ? 173 SER B O 1 ATOM 4474 C CB . SER B 1 175 ? -17.609 41.985 -33.130 1.00 41.53 ? 173 SER B CB 1 ATOM 4475 O OG . SER B 1 175 ? -18.432 42.635 -32.175 1.00 51.27 ? 173 SER B OG 1 ATOM 4476 N N . ASP B 1 176 ? -15.471 39.274 -33.380 1.00 38.81 ? 174 ASP B N 1 ATOM 4477 C CA . ASP B 1 176 ? -14.465 38.546 -34.144 1.00 39.98 ? 174 ASP B CA 1 ATOM 4478 C C . ASP B 1 176 ? -14.898 37.118 -34.373 1.00 44.67 ? 174 ASP B C 1 ATOM 4479 O O . ASP B 1 176 ? -14.824 36.305 -33.464 1.00 44.65 ? 174 ASP B O 1 ATOM 4480 C CB . ASP B 1 176 ? -13.085 38.587 -33.425 1.00 42.56 ? 174 ASP B CB 1 ATOM 4481 C CG . ASP B 1 176 ? -11.873 38.085 -34.217 1.00 53.53 ? 174 ASP B CG 1 ATOM 4482 O OD1 . ASP B 1 176 ? -12.063 37.556 -35.341 1.00 52.01 ? 174 ASP B OD1 1 ATOM 4483 O OD2 . ASP B 1 176 ? -10.733 38.221 -33.710 1.00 60.01 ? 174 ASP B OD2 1 ATOM 4484 N N . LYS B 1 177 ? -15.282 36.786 -35.603 1.00 42.04 ? 175 LYS B N 1 ATOM 4485 C CA . LYS B 1 177 ? -15.693 35.417 -35.885 1.00 41.79 ? 175 LYS B CA 1 ATOM 4486 C C . LYS B 1 177 ? -14.498 34.484 -36.149 1.00 47.32 ? 175 LYS B C 1 ATOM 4487 O O . LYS B 1 177 ? -14.692 33.287 -36.385 1.00 46.85 ? 175 LYS B O 1 ATOM 4488 C CB . LYS B 1 177 ? -16.759 35.351 -36.981 1.00 41.58 ? 175 LYS B CB 1 ATOM 4489 C CG . LYS B 1 177 ? -17.979 36.255 -36.730 1.00 40.66 ? 175 LYS B CG 1 ATOM 4490 C CD . LYS B 1 177 ? -18.820 35.883 -35.493 1.00 47.04 ? 175 LYS B CD 1 ATOM 4491 C CE . LYS B 1 177 ? -18.342 36.599 -34.253 1.00 40.76 ? 175 LYS B CE 1 ATOM 4492 N NZ . LYS B 1 177 ? -19.042 36.148 -33.041 1.00 38.41 ? 175 LYS B NZ 1 ATOM 4493 N N . SER B 1 178 ? -13.267 35.019 -36.026 1.00 44.50 ? 176 SER B N 1 ATOM 4494 C CA . SER B 1 178 ? -12.053 34.216 -36.189 1.00 43.90 ? 176 SER B CA 1 ATOM 4495 C C . SER B 1 178 ? -11.756 33.511 -34.866 1.00 44.62 ? 176 SER B C 1 ATOM 4496 O O . SER B 1 178 ? -11.181 32.431 -34.892 1.00 42.79 ? 176 SER B O 1 ATOM 4497 C CB . SER B 1 178 ? -10.877 35.064 -36.683 1.00 47.12 ? 176 SER B CB 1 ATOM 4498 O OG . SER B 1 178 ? -9.744 35.116 -35.827 1.00 53.52 ? 176 SER B OG 1 ATOM 4499 N N . ARG B 1 179 ? -12.251 34.058 -33.762 1.00 41.09 ? 177 ARG B N 1 ATOM 4500 C CA . ARG B 1 179 ? -12.077 33.479 -32.435 1.00 40.47 ? 177 ARG B CA 1 ATOM 4501 C C . ARG B 1 179 ? -13.329 33.012 -31.729 1.00 44.25 ? 177 ARG B C 1 ATOM 4502 O O . ARG B 1 179 ? -13.292 32.084 -30.984 1.00 47.18 ? 177 ARG B O 1 ATOM 4503 C CB . ARG B 1 179 ? -11.360 34.451 -31.525 1.00 39.35 ? 177 ARG B CB 1 ATOM 4504 C CG . ARG B 1 179 ? -10.289 35.224 -32.210 1.00 46.95 ? 177 ARG B CG 1 ATOM 4505 C CD . ARG B 1 179 ? -10.044 36.533 -31.537 1.00 59.00 ? 177 ARG B CD 1 ATOM 4506 N NE . ARG B 1 179 ? -9.273 36.321 -30.337 1.00 63.68 ? 177 ARG B NE 1 ATOM 4507 C CZ . ARG B 1 179 ? -8.857 37.301 -29.570 1.00 76.11 ? 177 ARG B CZ 1 ATOM 4508 N NH1 . ARG B 1 179 ? -9.145 38.535 -29.901 1.00 49.30 ? 177 ARG B NH1 1 ATOM 4509 N NH2 . ARG B 1 179 ? -8.177 37.049 -28.483 1.00 71.52 ? 177 ARG B NH2 1 ATOM 4510 N N . TYR B 1 180 ? -14.426 33.701 -31.934 1.00 39.26 ? 178 TYR B N 1 ATOM 4511 C CA . TYR B 1 180 ? -15.737 33.393 -31.310 1.00 38.41 ? 178 TYR B CA 1 ATOM 4512 C C . TYR B 1 180 ? -16.771 33.079 -32.400 1.00 43.97 ? 178 TYR B C 1 ATOM 4513 O O . TYR B 1 180 ? -17.778 33.781 -32.571 1.00 42.75 ? 178 TYR B O 1 ATOM 4514 C CB . TYR B 1 180 ? -16.186 34.553 -30.399 1.00 37.46 ? 178 TYR B CB 1 ATOM 4515 C CG . TYR B 1 180 ? -15.048 35.175 -29.615 1.00 37.32 ? 178 TYR B CG 1 ATOM 4516 C CD1 . TYR B 1 180 ? -14.520 34.543 -28.487 1.00 37.54 ? 178 TYR B CD1 1 ATOM 4517 C CD2 . TYR B 1 180 ? -14.507 36.412 -29.987 1.00 37.67 ? 178 TYR B CD2 1 ATOM 4518 C CE1 . TYR B 1 180 ? -13.484 35.121 -27.749 1.00 37.01 ? 178 TYR B CE1 1 ATOM 4519 C CE2 . TYR B 1 180 ? -13.467 36.996 -29.258 1.00 37.93 ? 178 TYR B CE2 1 ATOM 4520 C CZ . TYR B 1 180 ? -12.953 36.340 -28.145 1.00 46.15 ? 178 TYR B CZ 1 ATOM 4521 O OH . TYR B 1 180 ? -11.930 36.908 -27.414 1.00 50.95 ? 178 TYR B OH 1 ATOM 4522 N N . ASP B 1 181 ? -16.489 31.984 -33.140 1.00 40.50 ? 179 ASP B N 1 ATOM 4523 C CA . ASP B 1 181 ? -17.234 31.521 -34.314 1.00 37.96 ? 179 ASP B CA 1 ATOM 4524 C C . ASP B 1 181 ? -18.562 30.806 -34.001 1.00 37.46 ? 179 ASP B C 1 ATOM 4525 O O . ASP B 1 181 ? -19.298 30.503 -34.947 1.00 35.92 ? 179 ASP B O 1 ATOM 4526 C CB . ASP B 1 181 ? -16.329 30.673 -35.218 1.00 38.52 ? 179 ASP B CB 1 ATOM 4527 C CG . ASP B 1 181 ? -15.692 29.477 -34.561 1.00 51.09 ? 179 ASP B CG 1 ATOM 4528 O OD1 . ASP B 1 181 ? -15.132 29.635 -33.461 1.00 55.30 ? 179 ASP B OD1 1 ATOM 4529 O OD2 . ASP B 1 181 ? -15.701 28.389 -35.176 1.00 55.86 ? 179 ASP B OD2 1 ATOM 4530 N N . TYR B 1 182 ? -18.903 30.597 -32.709 1.00 33.00 ? 180 TYR B N 1 ATOM 4531 C CA . TYR B 1 182 ? -20.188 29.986 -32.302 1.00 33.73 ? 180 TYR B CA 1 ATOM 4532 C C . TYR B 1 182 ? -20.972 30.923 -31.384 1.00 39.63 ? 180 TYR B C 1 ATOM 4533 O O . TYR B 1 182 ? -21.900 30.509 -30.698 1.00 40.21 ? 180 TYR B O 1 ATOM 4534 C CB . TYR B 1 182 ? -19.971 28.600 -31.652 1.00 35.81 ? 180 TYR B CB 1 ATOM 4535 C CG . TYR B 1 182 ? -19.770 27.513 -32.678 1.00 37.17 ? 180 TYR B CG 1 ATOM 4536 C CD1 . TYR B 1 182 ? -18.507 27.252 -33.208 1.00 38.33 ? 180 TYR B CD1 1 ATOM 4537 C CD2 . TYR B 1 182 ? -20.853 26.821 -33.203 1.00 38.65 ? 180 TYR B CD2 1 ATOM 4538 C CE1 . TYR B 1 182 ? -18.330 26.326 -34.227 1.00 38.19 ? 180 TYR B CE1 1 ATOM 4539 C CE2 . TYR B 1 182 ? -20.693 25.913 -34.244 1.00 40.64 ? 180 TYR B CE2 1 ATOM 4540 C CZ . TYR B 1 182 ? -19.426 25.650 -34.738 1.00 50.97 ? 180 TYR B CZ 1 ATOM 4541 O OH . TYR B 1 182 ? -19.272 24.738 -35.754 1.00 55.15 ? 180 TYR B OH 1 ATOM 4542 N N . PHE B 1 183 ? -20.579 32.206 -31.377 1.00 36.50 ? 181 PHE B N 1 ATOM 4543 C CA . PHE B 1 183 ? -21.160 33.242 -30.528 1.00 34.34 ? 181 PHE B CA 1 ATOM 4544 C C . PHE B 1 183 ? -21.968 34.208 -31.353 1.00 37.39 ? 181 PHE B C 1 ATOM 4545 O O . PHE B 1 183 ? -21.569 34.592 -32.464 1.00 34.97 ? 181 PHE B O 1 ATOM 4546 C CB . PHE B 1 183 ? -20.058 33.995 -29.744 1.00 34.83 ? 181 PHE B CB 1 ATOM 4547 C CG . PHE B 1 183 ? -20.569 35.102 -28.856 1.00 35.36 ? 181 PHE B CG 1 ATOM 4548 C CD1 . PHE B 1 183 ? -20.721 36.400 -29.348 1.00 39.29 ? 181 PHE B CD1 1 ATOM 4549 C CD2 . PHE B 1 183 ? -20.888 34.857 -27.530 1.00 35.27 ? 181 PHE B CD2 1 ATOM 4550 C CE1 . PHE B 1 183 ? -21.212 37.423 -28.529 1.00 39.46 ? 181 PHE B CE1 1 ATOM 4551 C CE2 . PHE B 1 183 ? -21.364 35.878 -26.710 1.00 38.08 ? 181 PHE B CE2 1 ATOM 4552 C CZ . PHE B 1 183 ? -21.544 37.149 -27.219 1.00 36.96 ? 181 PHE B CZ 1 ATOM 4553 N N . ALA B 1 184 ? -23.112 34.595 -30.773 1.00 33.98 ? 182 ALA B N 1 ATOM 4554 C CA . ALA B 1 184 ? -24.080 35.560 -31.269 1.00 33.21 ? 182 ALA B CA 1 ATOM 4555 C C . ALA B 1 184 ? -24.682 36.240 -30.049 1.00 37.18 ? 182 ALA B C 1 ATOM 4556 O O . ALA B 1 184 ? -24.614 35.700 -28.939 1.00 33.53 ? 182 ALA B O 1 ATOM 4557 C CB . ALA B 1 184 ? -25.155 34.876 -32.097 1.00 33.53 ? 182 ALA B CB 1 ATOM 4558 N N . ARG B 1 185 ? -25.179 37.472 -30.239 1.00 36.29 ? 183 ARG B N 1 ATOM 4559 C CA . ARG B 1 185 ? -25.759 38.246 -29.153 1.00 37.42 ? 183 ARG B CA 1 ATOM 4560 C C . ARG B 1 185 ? -26.915 39.104 -29.595 1.00 42.74 ? 183 ARG B C 1 ATOM 4561 O O . ARG B 1 185 ? -26.935 39.552 -30.744 1.00 46.61 ? 183 ARG B O 1 ATOM 4562 C CB . ARG B 1 185 ? -24.697 39.069 -28.436 1.00 39.36 ? 183 ARG B CB 1 ATOM 4563 C CG . ARG B 1 185 ? -23.835 39.903 -29.351 1.00 44.35 ? 183 ARG B CG 1 ATOM 4564 C CD . ARG B 1 185 ? -22.986 40.841 -28.538 1.00 38.77 ? 183 ARG B CD 1 ATOM 4565 N NE . ARG B 1 185 ? -21.842 41.265 -29.330 1.00 35.87 ? 183 ARG B NE 1 ATOM 4566 C CZ . ARG B 1 185 ? -20.681 41.629 -28.818 1.00 35.16 ? 183 ARG B CZ 1 ATOM 4567 N NH1 . ARG B 1 185 ? -20.522 41.699 -27.509 1.00 29.06 ? 183 ARG B NH1 1 ATOM 4568 N NH2 . ARG B 1 185 ? -19.682 41.972 -29.613 1.00 21.94 ? 183 ARG B NH2 1 ATOM 4569 N N . THR B 1 186 ? -27.904 39.291 -28.722 1.00 35.66 ? 184 THR B N 1 ATOM 4570 C CA . THR B 1 186 ? -29.063 40.102 -29.064 1.00 35.28 ? 184 THR B CA 1 ATOM 4571 C C . THR B 1 186 ? -28.803 41.581 -28.730 1.00 44.68 ? 184 THR B C 1 ATOM 4572 O O . THR B 1 186 ? -29.605 42.451 -29.062 1.00 47.35 ? 184 THR B O 1 ATOM 4573 C CB . THR B 1 186 ? -30.337 39.525 -28.478 1.00 38.59 ? 184 THR B CB 1 ATOM 4574 O OG1 . THR B 1 186 ? -30.253 39.445 -27.042 1.00 41.71 ? 184 THR B OG1 1 ATOM 4575 C CG2 . THR B 1 186 ? -30.685 38.186 -29.097 1.00 30.51 ? 184 THR B CG2 1 ATOM 4576 N N . VAL B 1 187 ? -27.651 41.864 -28.127 1.00 40.94 ? 185 VAL B N 1 ATOM 4577 C CA . VAL B 1 187 ? -27.197 43.207 -27.795 1.00 39.19 ? 185 VAL B CA 1 ATOM 4578 C C . VAL B 1 187 ? -26.119 43.659 -28.832 1.00 44.48 ? 185 VAL B C 1 ATOM 4579 O O . VAL B 1 187 ? -25.432 42.791 -29.406 1.00 43.93 ? 185 VAL B O 1 ATOM 4580 C CB . VAL B 1 187 ? -26.654 43.280 -26.336 1.00 40.25 ? 185 VAL B CB 1 ATOM 4581 C CG1 . VAL B 1 187 ? -27.767 43.093 -25.329 1.00 39.05 ? 185 VAL B CG1 1 ATOM 4582 C CG2 . VAL B 1 187 ? -25.517 42.291 -26.090 1.00 39.47 ? 185 VAL B CG2 1 ATOM 4583 N N . PRO B 1 188 ? -25.921 44.987 -29.053 1.00 40.71 ? 186 PRO B N 1 ATOM 4584 C CA . PRO B 1 188 ? -24.859 45.423 -29.987 1.00 41.40 ? 186 PRO B CA 1 ATOM 4585 C C . PRO B 1 188 ? -23.472 45.469 -29.328 1.00 48.01 ? 186 PRO B C 1 ATOM 4586 O O . PRO B 1 188 ? -23.411 45.521 -28.103 1.00 49.97 ? 186 PRO B O 1 ATOM 4587 C CB . PRO B 1 188 ? -25.298 46.832 -30.376 1.00 43.06 ? 186 PRO B CB 1 ATOM 4588 C CG . PRO B 1 188 ? -26.080 47.327 -29.192 1.00 47.35 ? 186 PRO B CG 1 ATOM 4589 C CD . PRO B 1 188 ? -26.654 46.139 -28.485 1.00 42.31 ? 186 PRO B CD 1 ATOM 4590 N N . PRO B 1 189 ? -22.345 45.538 -30.071 1.00 44.20 ? 187 PRO B N 1 ATOM 4591 C CA . PRO B 1 189 ? -21.047 45.653 -29.387 1.00 44.76 ? 187 PRO B CA 1 ATOM 4592 C C . PRO B 1 189 ? -20.822 47.076 -28.831 1.00 52.84 ? 187 PRO B C 1 ATOM 4593 O O . PRO B 1 189 ? -21.480 48.041 -29.266 1.00 54.47 ? 187 PRO B O 1 ATOM 4594 C CB . PRO B 1 189 ? -20.046 45.336 -30.506 1.00 46.09 ? 187 PRO B CB 1 ATOM 4595 C CG . PRO B 1 189 ? -20.725 45.812 -31.749 1.00 49.55 ? 187 PRO B CG 1 ATOM 4596 C CD . PRO B 1 189 ? -22.181 45.513 -31.544 1.00 45.31 ? 187 PRO B CD 1 ATOM 4597 N N . ASP B 1 190 ? -19.852 47.222 -27.919 1.00 48.72 ? 188 ASP B N 1 ATOM 4598 C CA . ASP B 1 190 ? -19.523 48.512 -27.337 1.00 49.38 ? 188 ASP B CA 1 ATOM 4599 C C . ASP B 1 190 ? -18.858 49.493 -28.304 1.00 57.38 ? 188 ASP B C 1 ATOM 4600 O O . ASP B 1 190 ? -18.702 50.675 -27.957 1.00 57.13 ? 188 ASP B O 1 ATOM 4601 C CB . ASP B 1 190 ? -18.708 48.347 -26.069 1.00 50.60 ? 188 ASP B CB 1 ATOM 4602 C CG . ASP B 1 190 ? -19.591 47.899 -24.932 1.00 57.62 ? 188 ASP B CG 1 ATOM 4603 O OD1 . ASP B 1 190 ? -20.824 48.156 -24.995 1.00 56.34 ? 188 ASP B OD1 1 ATOM 4604 O OD2 . ASP B 1 190 ? -19.075 47.229 -24.017 1.00 65.15 ? 188 ASP B OD2 1 ATOM 4605 N N . PHE B 1 191 ? -18.559 49.031 -29.547 1.00 55.21 ? 189 PHE B N 1 ATOM 4606 C CA . PHE B 1 191 ? -18.004 49.850 -30.613 1.00 54.82 ? 189 PHE B CA 1 ATOM 4607 C C . PHE B 1 191 ? -18.912 51.064 -30.811 1.00 60.58 ? 189 PHE B C 1 ATOM 4608 O O . PHE B 1 191 ? -18.430 52.189 -30.832 1.00 59.67 ? 189 PHE B O 1 ATOM 4609 C CB . PHE B 1 191 ? -17.905 49.021 -31.890 1.00 56.38 ? 189 PHE B CB 1 ATOM 4610 C CG . PHE B 1 191 ? -17.603 49.807 -33.145 1.00 58.48 ? 189 PHE B CG 1 ATOM 4611 C CD1 . PHE B 1 191 ? -16.308 50.243 -33.418 1.00 61.65 ? 189 PHE B CD1 1 ATOM 4612 C CD2 . PHE B 1 191 ? -18.607 50.080 -34.074 1.00 60.42 ? 189 PHE B CD2 1 ATOM 4613 C CE1 . PHE B 1 191 ? -16.026 50.945 -34.590 1.00 62.39 ? 189 PHE B CE1 1 ATOM 4614 C CE2 . PHE B 1 191 ? -18.325 50.782 -35.243 1.00 62.93 ? 189 PHE B CE2 1 ATOM 4615 C CZ . PHE B 1 191 ? -17.036 51.208 -35.496 1.00 61.21 ? 189 PHE B CZ 1 ATOM 4616 N N . PHE B 1 192 ? -20.228 50.811 -30.871 1.00 59.80 ? 190 PHE B N 1 ATOM 4617 C CA . PHE B 1 192 ? -21.311 51.766 -31.039 1.00 60.72 ? 190 PHE B CA 1 ATOM 4618 C C . PHE B 1 192 ? -21.653 52.503 -29.743 1.00 63.51 ? 190 PHE B C 1 ATOM 4619 O O . PHE B 1 192 ? -22.152 53.626 -29.821 1.00 62.97 ? 190 PHE B O 1 ATOM 4620 C CB . PHE B 1 192 ? -22.558 51.036 -31.553 1.00 63.87 ? 190 PHE B CB 1 ATOM 4621 C CG . PHE B 1 192 ? -22.430 50.462 -32.942 1.00 66.72 ? 190 PHE B CG 1 ATOM 4622 C CD1 . PHE B 1 192 ? -21.980 49.164 -33.135 1.00 70.22 ? 190 PHE B CD1 1 ATOM 4623 C CD2 . PHE B 1 192 ? -22.787 51.214 -34.059 1.00 70.27 ? 190 PHE B CD2 1 ATOM 4624 C CE1 . PHE B 1 192 ? -21.857 48.638 -34.424 1.00 72.03 ? 190 PHE B CE1 1 ATOM 4625 C CE2 . PHE B 1 192 ? -22.670 50.684 -35.348 1.00 73.40 ? 190 PHE B CE2 1 ATOM 4626 C CZ . PHE B 1 192 ? -22.206 49.400 -35.521 1.00 71.44 ? 190 PHE B CZ 1 ATOM 4627 N N . GLN B 1 193 ? -21.428 51.887 -28.551 1.00 58.78 ? 191 GLN B N 1 ATOM 4628 C CA . GLN B 1 193 ? -21.744 52.598 -27.296 1.00 57.24 ? 191 GLN B CA 1 ATOM 4629 C C . GLN B 1 193 ? -20.799 53.767 -27.147 1.00 59.16 ? 191 GLN B C 1 ATOM 4630 O O . GLN B 1 193 ? -21.262 54.899 -27.047 1.00 57.84 ? 191 GLN B O 1 ATOM 4631 C CB . GLN B 1 193 ? -21.703 51.687 -26.062 1.00 58.02 ? 191 GLN B CB 1 ATOM 4632 C CG . GLN B 1 193 ? -22.438 52.318 -24.873 1.00 61.70 ? 191 GLN B CG 1 ATOM 4633 C CD . GLN B 1 193 ? -22.664 51.439 -23.656 1.00 68.08 ? 191 GLN B CD 1 ATOM 4634 O OE1 . GLN B 1 193 ? -23.141 51.911 -22.625 1.00 50.34 ? 191 GLN B OE1 1 ATOM 4635 N NE2 . GLN B 1 193 ? -22.354 50.149 -23.727 1.00 67.33 ? 191 GLN B NE2 1 ATOM 4636 N N . ALA B 1 194 ? -19.475 53.485 -27.241 1.00 55.06 ? 192 ALA B N 1 ATOM 4637 C CA . ALA B 1 194 ? -18.358 54.438 -27.211 1.00 54.60 ? 192 ALA B CA 1 ATOM 4638 C C . ALA B 1 194 ? -18.543 55.577 -28.239 1.00 57.82 ? 192 ALA B C 1 ATOM 4639 O O . ALA B 1 194 ? -18.425 56.753 -27.883 1.00 55.05 ? 192 ALA B O 1 ATOM 4640 C CB . ALA B 1 194 ? -17.064 53.696 -27.479 1.00 55.24 ? 192 ALA B CB 1 ATOM 4641 N N . LYS B 1 195 ? -18.919 55.204 -29.487 1.00 56.93 ? 193 LYS B N 1 ATOM 4642 C CA . LYS B 1 195 ? -19.240 56.069 -30.624 1.00 58.41 ? 193 LYS B CA 1 ATOM 4643 C C . LYS B 1 195 ? -20.357 57.045 -30.233 1.00 66.02 ? 193 LYS B C 1 ATOM 4644 O O . LYS B 1 195 ? -20.311 58.200 -30.650 1.00 66.52 ? 193 LYS B O 1 ATOM 4645 C CB . LYS B 1 195 ? -19.694 55.196 -31.812 1.00 62.27 ? 193 LYS B CB 1 ATOM 4646 C CG . LYS B 1 195 ? -20.036 55.952 -33.104 1.00 82.47 ? 193 LYS B CG 1 ATOM 4647 C CD . LYS B 1 195 ? -19.043 55.709 -34.233 1.00 88.83 ? 193 LYS B CD 1 ATOM 4648 C CE . LYS B 1 195 ? -19.331 54.493 -35.075 1.00 93.01 ? 193 LYS B CE 1 ATOM 4649 N NZ . LYS B 1 195 ? -18.248 54.277 -36.067 1.00 101.75 ? 193 LYS B NZ 1 ATOM 4650 N N . ALA B 1 196 ? -21.353 56.580 -29.427 1.00 63.20 ? 194 ALA B N 1 ATOM 4651 C CA . ALA B 1 196 ? -22.451 57.411 -28.928 1.00 62.14 ? 194 ALA B CA 1 ATOM 4652 C C . ALA B 1 196 ? -21.935 58.366 -27.837 1.00 64.30 ? 194 ALA B C 1 ATOM 4653 O O . ALA B 1 196 ? -22.195 59.573 -27.925 1.00 62.79 ? 194 ALA B O 1 ATOM 4654 C CB . ALA B 1 196 ? -23.555 56.537 -28.370 1.00 62.64 ? 194 ALA B CB 1 ATOM 4655 N N . MET B 1 197 ? -21.198 57.826 -26.829 1.00 60.29 ? 195 MET B N 1 ATOM 4656 C CA . MET B 1 197 ? -20.631 58.584 -25.710 1.00 61.13 ? 195 MET B CA 1 ATOM 4657 C C . MET B 1 197 ? -19.784 59.757 -26.195 1.00 68.11 ? 195 MET B C 1 ATOM 4658 O O . MET B 1 197 ? -19.960 60.884 -25.722 1.00 67.52 ? 195 MET B O 1 ATOM 4659 C CB . MET B 1 197 ? -19.807 57.681 -24.777 1.00 63.81 ? 195 MET B CB 1 ATOM 4660 C CG . MET B 1 197 ? -20.648 56.901 -23.783 1.00 68.20 ? 195 MET B CG 1 ATOM 4661 S SD . MET B 1 197 ? -19.745 55.510 -23.032 1.00 73.60 ? 195 MET B SD 1 ATOM 4662 C CE . MET B 1 197 ? -19.241 56.232 -21.499 1.00 70.13 ? 195 MET B CE 1 ATOM 4663 N N . ALA B 1 198 ? -18.899 59.499 -27.179 1.00 66.32 ? 196 ALA B N 1 ATOM 4664 C CA . ALA B 1 198 ? -18.051 60.525 -27.767 1.00 65.51 ? 196 ALA B CA 1 ATOM 4665 C C . ALA B 1 198 ? -18.899 61.530 -28.546 1.00 70.40 ? 196 ALA B C 1 ATOM 4666 O O . ALA B 1 198 ? -18.610 62.719 -28.467 1.00 70.49 ? 196 ALA B O 1 ATOM 4667 C CB . ALA B 1 198 ? -16.991 59.892 -28.652 1.00 65.97 ? 196 ALA B CB 1 ATOM 4668 N N . GLU B 1 199 ? -19.980 61.076 -29.239 1.00 68.14 ? 197 GLU B N 1 ATOM 4669 C CA . GLU B 1 199 ? -20.886 61.963 -29.991 1.00 68.62 ? 197 GLU B CA 1 ATOM 4670 C C . GLU B 1 199 ? -21.652 62.947 -29.088 1.00 76.26 ? 197 GLU B C 1 ATOM 4671 O O . GLU B 1 199 ? -21.937 64.067 -29.522 1.00 77.50 ? 197 GLU B O 1 ATOM 4672 C CB . GLU B 1 199 ? -21.843 61.188 -30.906 1.00 69.59 ? 197 GLU B CB 1 ATOM 4673 C CG . GLU B 1 199 ? -21.230 60.883 -32.263 1.00 77.99 ? 197 GLU B CG 1 ATOM 4674 C CD . GLU B 1 199 ? -22.170 60.532 -33.405 1.00 96.16 ? 197 GLU B CD 1 ATOM 4675 O OE1 . GLU B 1 199 ? -23.311 61.047 -33.424 1.00 96.35 ? 197 GLU B OE1 1 ATOM 4676 O OE2 . GLU B 1 199 ? -21.739 59.792 -34.321 1.00 82.07 ? 197 GLU B OE2 1 ATOM 4677 N N . ILE B 1 200 ? -21.948 62.546 -27.830 1.00 72.64 ? 198 ILE B N 1 ATOM 4678 C CA . ILE B 1 200 ? -22.609 63.399 -26.837 1.00 71.97 ? 198 ILE B CA 1 ATOM 4679 C C . ILE B 1 200 ? -21.663 64.556 -26.513 1.00 75.28 ? 198 ILE B C 1 ATOM 4680 O O . ILE B 1 200 ? -22.080 65.709 -26.580 1.00 76.03 ? 198 ILE B O 1 ATOM 4681 C CB . ILE B 1 200 ? -23.027 62.604 -25.556 1.00 74.83 ? 198 ILE B CB 1 ATOM 4682 C CG1 . ILE B 1 200 ? -24.067 61.524 -25.888 1.00 75.07 ? 198 ILE B CG1 1 ATOM 4683 C CG2 . ILE B 1 200 ? -23.544 63.536 -24.436 1.00 75.15 ? 198 ILE B CG2 1 ATOM 4684 C CD1 . ILE B 1 200 ? -24.107 60.418 -24.898 1.00 79.74 ? 198 ILE B CD1 1 ATOM 4685 N N . LEU B 1 201 ? -20.392 64.242 -26.205 1.00 70.63 ? 199 LEU B N 1 ATOM 4686 C CA . LEU B 1 201 ? -19.339 65.204 -25.867 1.00 70.44 ? 199 LEU B CA 1 ATOM 4687 C C . LEU B 1 201 ? -19.114 66.278 -26.951 1.00 76.72 ? 199 LEU B C 1 ATOM 4688 O O . LEU B 1 201 ? -19.084 67.469 -26.616 1.00 76.90 ? 199 LEU B O 1 ATOM 4689 C CB . LEU B 1 201 ? -18.038 64.469 -25.526 1.00 69.90 ? 199 LEU B CB 1 ATOM 4690 C CG . LEU B 1 201 ? -17.800 64.115 -24.059 1.00 74.23 ? 199 LEU B CG 1 ATOM 4691 C CD1 . LEU B 1 201 ? -18.871 63.171 -23.501 1.00 74.53 ? 199 LEU B CD1 1 ATOM 4692 C CD2 . LEU B 1 201 ? -16.470 63.464 -23.897 1.00 75.85 ? 199 LEU B CD2 1 ATOM 4693 N N . ARG B 1 202 ? -19.031 65.864 -28.239 1.00 74.07 ? 200 ARG B N 1 ATOM 4694 C CA . ARG B 1 202 ? -18.864 66.760 -29.395 1.00 74.86 ? 200 ARG B CA 1 ATOM 4695 C C . ARG B 1 202 ? -20.039 67.738 -29.546 1.00 79.92 ? 200 ARG B C 1 ATOM 4696 O O . ARG B 1 202 ? -19.817 68.897 -29.908 1.00 79.89 ? 200 ARG B O 1 ATOM 4697 C CB . ARG B 1 202 ? -18.679 65.962 -30.698 1.00 76.06 ? 200 ARG B CB 1 ATOM 4698 N N . PHE B 1 203 ? -21.282 67.263 -29.270 1.00 76.32 ? 201 PHE B N 1 ATOM 4699 C CA . PHE B 1 203 ? -22.513 68.052 -29.315 1.00 76.36 ? 201 PHE B CA 1 ATOM 4700 C C . PHE B 1 203 ? -22.487 69.123 -28.228 1.00 80.11 ? 201 PHE B C 1 ATOM 4701 O O . PHE B 1 203 ? -22.981 70.233 -28.435 1.00 79.95 ? 201 PHE B O 1 ATOM 4702 C CB . PHE B 1 203 ? -23.725 67.135 -29.103 1.00 78.62 ? 201 PHE B CB 1 ATOM 4703 C CG . PHE B 1 203 ? -25.088 67.789 -28.986 1.00 80.85 ? 201 PHE B CG 1 ATOM 4704 C CD1 . PHE B 1 203 ? -25.515 68.342 -27.780 1.00 84.07 ? 201 PHE B CD1 1 ATOM 4705 C CD2 . PHE B 1 203 ? -25.985 67.760 -30.050 1.00 83.44 ? 201 PHE B CD2 1 ATOM 4706 C CE1 . PHE B 1 203 ? -26.789 68.908 -27.662 1.00 85.06 ? 201 PHE B CE1 1 ATOM 4707 C CE2 . PHE B 1 203 ? -27.267 68.313 -29.925 1.00 86.23 ? 201 PHE B CE2 1 ATOM 4708 C CZ . PHE B 1 203 ? -27.660 68.882 -28.731 1.00 84.16 ? 201 PHE B CZ 1 ATOM 4709 N N . PHE B 1 204 ? -21.951 68.765 -27.059 1.00 76.05 ? 202 PHE B N 1 ATOM 4710 C CA . PHE B 1 204 ? -21.863 69.660 -25.928 1.00 75.36 ? 202 PHE B CA 1 ATOM 4711 C C . PHE B 1 204 ? -20.556 70.424 -25.879 1.00 81.80 ? 202 PHE B C 1 ATOM 4712 O O . PHE B 1 204 ? -20.330 71.183 -24.934 1.00 82.08 ? 202 PHE B O 1 ATOM 4713 C CB . PHE B 1 204 ? -22.129 68.899 -24.634 1.00 76.47 ? 202 PHE B CB 1 ATOM 4714 C CG . PHE B 1 204 ? -23.585 68.602 -24.386 1.00 77.67 ? 202 PHE B CG 1 ATOM 4715 C CD1 . PHE B 1 204 ? -24.555 69.579 -24.583 1.00 79.97 ? 202 PHE B CD1 1 ATOM 4716 C CD2 . PHE B 1 204 ? -23.988 67.351 -23.931 1.00 79.76 ? 202 PHE B CD2 1 ATOM 4717 C CE1 . PHE B 1 204 ? -25.899 69.310 -24.339 1.00 80.62 ? 202 PHE B CE1 1 ATOM 4718 C CE2 . PHE B 1 204 ? -25.335 67.082 -23.688 1.00 82.18 ? 202 PHE B CE2 1 ATOM 4719 C CZ . PHE B 1 204 ? -26.279 68.065 -23.892 1.00 80.24 ? 202 PHE B CZ 1 ATOM 4720 N N . ASN B 1 205 ? -19.708 70.257 -26.911 1.00 79.79 ? 203 ASN B N 1 ATOM 4721 C CA . ASN B 1 205 ? -18.412 70.935 -27.061 1.00 80.57 ? 203 ASN B CA 1 ATOM 4722 C C . ASN B 1 205 ? -17.460 70.699 -25.850 1.00 85.55 ? 203 ASN B C 1 ATOM 4723 O O . ASN B 1 205 ? -16.743 71.614 -25.419 1.00 85.05 ? 203 ASN B O 1 ATOM 4724 C CB . ASN B 1 205 ? -18.602 72.443 -27.386 1.00 80.92 ? 203 ASN B CB 1 ATOM 4725 C CG . ASN B 1 205 ? -19.437 72.711 -28.623 1.00 101.23 ? 203 ASN B CG 1 ATOM 4726 O OD1 . ASN B 1 205 ? -18.998 72.494 -29.759 1.00 92.58 ? 203 ASN B OD1 1 ATOM 4727 N ND2 . ASN B 1 205 ? -20.650 73.223 -28.433 1.00 92.86 ? 203 ASN B ND2 1 ATOM 4728 N N . TRP B 1 206 ? -17.454 69.452 -25.328 1.00 82.75 ? 204 TRP B N 1 ATOM 4729 C CA . TRP B 1 206 ? -16.601 69.028 -24.212 1.00 82.95 ? 204 TRP B CA 1 ATOM 4730 C C . TRP B 1 206 ? -15.308 68.433 -24.781 1.00 85.99 ? 204 TRP B C 1 ATOM 4731 O O . TRP B 1 206 ? -15.233 67.231 -25.057 1.00 85.28 ? 204 TRP B O 1 ATOM 4732 C CB . TRP B 1 206 ? -17.347 68.041 -23.292 1.00 82.18 ? 204 TRP B CB 1 ATOM 4733 C CG . TRP B 1 206 ? -18.613 68.591 -22.688 1.00 83.61 ? 204 TRP B CG 1 ATOM 4734 C CD1 . TRP B 1 206 ? -18.941 69.905 -22.519 1.00 86.56 ? 204 TRP B CD1 1 ATOM 4735 C CD2 . TRP B 1 206 ? -19.703 67.832 -22.143 1.00 83.57 ? 204 TRP B CD2 1 ATOM 4736 N NE1 . TRP B 1 206 ? -20.179 70.012 -21.928 1.00 86.14 ? 204 TRP B NE1 1 ATOM 4737 C CE2 . TRP B 1 206 ? -20.651 68.756 -21.647 1.00 87.53 ? 204 TRP B CE2 1 ATOM 4738 C CE3 . TRP B 1 206 ? -19.964 66.459 -22.008 1.00 84.90 ? 204 TRP B CE3 1 ATOM 4739 C CZ2 . TRP B 1 206 ? -21.858 68.353 -21.063 1.00 86.81 ? 204 TRP B CZ2 1 ATOM 4740 C CZ3 . TRP B 1 206 ? -21.140 66.062 -21.387 1.00 86.46 ? 204 TRP B CZ3 1 ATOM 4741 C CH2 . TRP B 1 206 ? -22.071 67.002 -20.924 1.00 87.04 ? 204 TRP B CH2 1 ATOM 4742 N N . THR B 1 207 ? -14.304 69.307 -24.995 1.00 81.85 ? 205 THR B N 1 ATOM 4743 C CA . THR B 1 207 ? -13.009 68.979 -25.601 1.00 80.87 ? 205 THR B CA 1 ATOM 4744 C C . THR B 1 207 ? -11.987 68.442 -24.574 1.00 82.65 ? 205 THR B C 1 ATOM 4745 O O . THR B 1 207 ? -11.147 67.633 -24.952 1.00 82.23 ? 205 THR B O 1 ATOM 4746 C CB . THR B 1 207 ? -12.506 70.193 -26.413 1.00 88.18 ? 205 THR B CB 1 ATOM 4747 O OG1 . THR B 1 207 ? -13.444 70.431 -27.459 1.00 82.77 ? 205 THR B OG1 1 ATOM 4748 C CG2 . THR B 1 207 ? -11.122 69.981 -27.041 1.00 90.21 ? 205 THR B CG2 1 ATOM 4749 N N . TYR B 1 208 ? -12.093 68.792 -23.308 1.00 78.03 ? 206 TYR B N 1 ATOM 4750 C CA . TYR B 1 208 ? -11.176 68.243 -22.323 1.00 77.71 ? 206 TYR B CA 1 ATOM 4751 C C . TYR B 1 208 ? -11.922 67.441 -21.283 1.00 81.28 ? 206 TYR B C 1 ATOM 4752 O O . TYR B 1 208 ? -12.803 67.972 -20.631 1.00 80.84 ? 206 TYR B O 1 ATOM 4753 C CB . TYR B 1 208 ? -10.413 69.372 -21.653 1.00 78.84 ? 206 TYR B CB 1 ATOM 4754 C CG . TYR B 1 208 ? -9.114 68.977 -21.025 1.00 80.80 ? 206 TYR B CG 1 ATOM 4755 C CD1 . TYR B 1 208 ? -8.081 68.492 -21.778 1.00 82.92 ? 206 TYR B CD1 1 ATOM 4756 C CD2 . TYR B 1 208 ? -8.920 69.112 -19.676 1.00 81.88 ? 206 TYR B CD2 1 ATOM 4757 C CE1 . TYR B 1 208 ? -6.887 68.133 -21.195 1.00 85.25 ? 206 TYR B CE1 1 ATOM 4758 C CE2 . TYR B 1 208 ? -7.732 68.763 -19.083 1.00 82.95 ? 206 TYR B CE2 1 ATOM 4759 C CZ . TYR B 1 208 ? -6.721 68.272 -19.846 1.00 91.99 ? 206 TYR B CZ 1 ATOM 4760 O OH . TYR B 1 208 ? -5.544 67.928 -19.248 1.00 93.47 ? 206 TYR B OH 1 ATOM 4761 N N . VAL B 1 209 ? -11.560 66.163 -21.133 1.00 77.85 ? 207 VAL B N 1 ATOM 4762 C CA . VAL B 1 209 ? -12.283 65.207 -20.287 1.00 76.97 ? 207 VAL B CA 1 ATOM 4763 C C . VAL B 1 209 ? -11.437 64.030 -19.841 1.00 78.80 ? 207 VAL B C 1 ATOM 4764 O O . VAL B 1 209 ? -10.379 63.806 -20.369 1.00 78.97 ? 207 VAL B O 1 ATOM 4765 C CB . VAL B 1 209 ? -13.473 64.642 -21.045 1.00 80.40 ? 207 VAL B CB 1 ATOM 4766 C CG1 . VAL B 1 209 ? -14.350 65.775 -21.525 1.00 79.95 ? 207 VAL B CG1 1 ATOM 4767 C CG2 . VAL B 1 209 ? -12.989 63.829 -22.225 1.00 80.15 ? 207 VAL B CG2 1 ATOM 4768 N N . SER B 1 210 ? -11.921 63.264 -18.879 1.00 73.03 ? 208 SER B N 1 ATOM 4769 C CA . SER B 1 210 ? -11.185 62.105 -18.410 1.00 72.13 ? 208 SER B CA 1 ATOM 4770 C C . SER B 1 210 ? -11.994 60.815 -18.436 1.00 76.40 ? 208 SER B C 1 ATOM 4771 O O . SER B 1 210 ? -13.157 60.804 -18.809 1.00 76.33 ? 208 SER B O 1 ATOM 4772 C CB . SER B 1 210 ? -10.709 62.364 -17.019 1.00 74.17 ? 208 SER B CB 1 ATOM 4773 O OG . SER B 1 210 ? -11.368 63.497 -16.547 1.00 81.73 ? 208 SER B OG 1 ATOM 4774 N N . THR B 1 211 ? -11.356 59.721 -18.038 1.00 71.48 ? 209 THR B N 1 ATOM 4775 C CA . THR B 1 211 ? -11.953 58.417 -18.154 1.00 69.92 ? 209 THR B CA 1 ATOM 4776 C C . THR B 1 211 ? -11.694 57.536 -16.984 1.00 72.49 ? 209 THR B C 1 ATOM 4777 O O . THR B 1 211 ? -10.580 57.455 -16.530 1.00 72.64 ? 209 THR B O 1 ATOM 4778 C CB . THR B 1 211 ? -11.346 57.664 -19.322 1.00 71.33 ? 209 THR B CB 1 ATOM 4779 O OG1 . THR B 1 211 ? -9.973 57.416 -19.056 1.00 67.42 ? 209 THR B OG1 1 ATOM 4780 C CG2 . THR B 1 211 ? -11.463 58.457 -20.554 1.00 68.84 ? 209 THR B CG2 1 ATOM 4781 N N . VAL B 1 212 ? -12.704 56.808 -16.549 1.00 67.04 ? 210 VAL B N 1 ATOM 4782 C CA . VAL B 1 212 ? -12.462 55.732 -15.630 1.00 65.57 ? 210 VAL B CA 1 ATOM 4783 C C . VAL B 1 212 ? -12.943 54.459 -16.270 1.00 68.56 ? 210 VAL B C 1 ATOM 4784 O O . VAL B 1 212 ? -13.643 54.504 -17.240 1.00 67.23 ? 210 VAL B O 1 ATOM 4785 C CB . VAL B 1 212 ? -13.179 55.925 -14.319 1.00 68.09 ? 210 VAL B CB 1 ATOM 4786 C CG1 . VAL B 1 212 ? -12.715 54.877 -13.346 1.00 67.67 ? 210 VAL B CG1 1 ATOM 4787 C CG2 . VAL B 1 212 ? -12.883 57.292 -13.786 1.00 67.48 ? 210 VAL B CG2 1 ATOM 4788 N N . ALA B 1 213 ? -12.547 53.323 -15.725 1.00 65.42 ? 211 ALA B N 1 ATOM 4789 C CA . ALA B 1 213 ? -12.879 52.050 -16.328 1.00 65.05 ? 211 ALA B CA 1 ATOM 4790 C C . ALA B 1 213 ? -12.391 50.872 -15.513 1.00 68.47 ? 211 ALA B C 1 ATOM 4791 O O . ALA B 1 213 ? -11.340 50.926 -14.920 1.00 66.41 ? 211 ALA B O 1 ATOM 4792 C CB . ALA B 1 213 ? -12.305 51.985 -17.710 1.00 65.76 ? 211 ALA B CB 1 ATOM 4793 N N . SER B 1 214 ? -13.130 49.801 -15.483 1.00 64.71 ? 212 SER B N 1 ATOM 4794 C CA . SER B 1 214 ? -12.857 48.663 -14.636 1.00 64.07 ? 212 SER B CA 1 ATOM 4795 C C . SER B 1 214 ? -12.020 47.561 -15.272 1.00 68.48 ? 212 SER B C 1 ATOM 4796 O O . SER B 1 214 ? -12.029 47.372 -16.467 1.00 67.49 ? 212 SER B O 1 ATOM 4797 C CB . SER B 1 214 ? -14.175 48.096 -14.176 1.00 65.81 ? 212 SER B CB 1 ATOM 4798 O OG . SER B 1 214 ? -15.151 48.365 -15.138 1.00 67.64 ? 212 SER B OG 1 ATOM 4799 N N . GLU B 1 215 ? -11.336 46.828 -14.468 1.00 66.03 ? 213 GLU B N 1 ATOM 4800 C CA . GLU B 1 215 ? -10.575 45.705 -14.950 1.00 66.86 ? 213 GLU B CA 1 ATOM 4801 C C . GLU B 1 215 ? -11.538 44.703 -15.521 1.00 71.18 ? 213 GLU B C 1 ATOM 4802 O O . GLU B 1 215 ? -12.519 44.337 -14.893 1.00 71.85 ? 213 GLU B O 1 ATOM 4803 C CB . GLU B 1 215 ? -9.745 45.074 -13.830 1.00 68.68 ? 213 GLU B CB 1 ATOM 4804 C CG . GLU B 1 215 ? -9.343 43.618 -14.055 1.00 84.25 ? 213 GLU B CG 1 ATOM 4805 C CD . GLU B 1 215 ? -8.515 43.052 -12.918 1.00 108.91 ? 213 GLU B CD 1 ATOM 4806 O OE1 . GLU B 1 215 ? -8.312 41.829 -12.868 1.00 88.60 ? 213 GLU B OE1 1 ATOM 4807 O OE2 . GLU B 1 215 ? -8.059 43.834 -12.071 1.00 108.84 ? 213 GLU B OE2 1 ATOM 4808 N N . GLY B 1 216 ? -11.244 44.255 -16.725 1.00 65.07 ? 214 GLY B N 1 ATOM 4809 C CA . GLY B 1 216 ? -12.033 43.237 -17.390 1.00 63.58 ? 214 GLY B CA 1 ATOM 4810 C C . GLY B 1 216 ? -12.168 43.595 -18.838 1.00 65.43 ? 214 GLY B C 1 ATOM 4811 O O . GLY B 1 216 ? -11.909 44.740 -19.226 1.00 65.00 ? 214 GLY B O 1 ATOM 4812 N N . ASP B 1 217 ? -12.588 42.624 -19.636 1.00 61.03 ? 215 ASP B N 1 ATOM 4813 C CA . ASP B 1 217 ? -12.730 42.807 -21.064 1.00 61.08 ? 215 ASP B CA 1 ATOM 4814 C C . ASP B 1 217 ? -13.636 43.976 -21.427 1.00 64.43 ? 215 ASP B C 1 ATOM 4815 O O . ASP B 1 217 ? -13.157 44.903 -22.066 1.00 66.04 ? 215 ASP B O 1 ATOM 4816 C CB . ASP B 1 217 ? -13.143 41.514 -21.756 1.00 63.58 ? 215 ASP B CB 1 ATOM 4817 C CG . ASP B 1 217 ? -12.193 41.238 -22.882 1.00 78.07 ? 215 ASP B CG 1 ATOM 4818 O OD1 . ASP B 1 217 ? -12.149 42.057 -23.823 1.00 81.55 ? 215 ASP B OD1 1 ATOM 4819 O OD2 . ASP B 1 217 ? -11.397 40.274 -22.765 1.00 79.98 ? 215 ASP B OD2 1 ATOM 4820 N N . TYR B 1 218 ? -14.887 43.994 -20.930 1.00 57.14 ? 216 TYR B N 1 ATOM 4821 C CA . TYR B 1 218 ? -15.871 45.073 -21.135 1.00 54.05 ? 216 TYR B CA 1 ATOM 4822 C C . TYR B 1 218 ? -15.332 46.522 -20.990 1.00 58.18 ? 216 TYR B C 1 ATOM 4823 O O . TYR B 1 218 ? -15.425 47.296 -21.941 1.00 57.82 ? 216 TYR B O 1 ATOM 4824 C CB . TYR B 1 218 ? -17.063 44.862 -20.181 1.00 51.39 ? 216 TYR B CB 1 ATOM 4825 C CG . TYR B 1 218 ? -18.001 46.040 -20.022 1.00 48.24 ? 216 TYR B CG 1 ATOM 4826 C CD1 . TYR B 1 218 ? -18.926 46.355 -21.010 1.00 49.23 ? 216 TYR B CD1 1 ATOM 4827 C CD2 . TYR B 1 218 ? -18.036 46.776 -18.837 1.00 47.81 ? 216 TYR B CD2 1 ATOM 4828 C CE1 . TYR B 1 218 ? -19.849 47.382 -20.834 1.00 50.08 ? 216 TYR B CE1 1 ATOM 4829 C CE2 . TYR B 1 218 ? -18.938 47.826 -18.659 1.00 47.37 ? 216 TYR B CE2 1 ATOM 4830 C CZ . TYR B 1 218 ? -19.849 48.119 -19.658 1.00 50.77 ? 216 TYR B CZ 1 ATOM 4831 O OH . TYR B 1 218 ? -20.772 49.115 -19.485 1.00 42.27 ? 216 TYR B OH 1 ATOM 4832 N N . GLY B 1 219 ? -14.857 46.867 -19.789 1.00 54.05 ? 217 GLY B N 1 ATOM 4833 C CA . GLY B 1 219 ? -14.431 48.209 -19.430 1.00 54.08 ? 217 GLY B CA 1 ATOM 4834 C C . GLY B 1 219 ? -13.190 48.683 -20.136 1.00 59.81 ? 217 GLY B C 1 ATOM 4835 O O . GLY B 1 219 ? -13.210 49.747 -20.771 1.00 58.41 ? 217 GLY B O 1 ATOM 4836 N N . GLU B 1 220 ? -12.091 47.893 -20.000 1.00 58.48 ? 218 GLU B N 1 ATOM 4837 C CA . GLU B 1 220 ? -10.784 48.163 -20.620 1.00 58.09 ? 218 GLU B CA 1 ATOM 4838 C C . GLU B 1 220 ? -10.952 48.403 -22.128 1.00 62.91 ? 218 GLU B C 1 ATOM 4839 O O . GLU B 1 220 ? -10.712 49.530 -22.592 1.00 64.44 ? 218 GLU B O 1 ATOM 4840 C CB . GLU B 1 220 ? -9.779 47.042 -20.312 1.00 59.17 ? 218 GLU B CB 1 ATOM 4841 C CG . GLU B 1 220 ? -9.451 46.887 -18.827 1.00 63.72 ? 218 GLU B CG 1 ATOM 4842 C CD . GLU B 1 220 ? -8.139 46.182 -18.526 1.00 79.65 ? 218 GLU B CD 1 ATOM 4843 O OE1 . GLU B 1 220 ? -7.077 46.718 -18.917 1.00 91.56 ? 218 GLU B OE1 1 ATOM 4844 O OE2 . GLU B 1 220 ? -8.162 45.130 -17.847 1.00 66.39 ? 218 GLU B OE2 1 ATOM 4845 N N . THR B 1 221 ? -11.524 47.409 -22.853 1.00 57.23 ? 219 THR B N 1 ATOM 4846 C CA . THR B 1 221 ? -11.795 47.494 -24.298 1.00 56.13 ? 219 THR B CA 1 ATOM 4847 C C . THR B 1 221 ? -12.936 48.468 -24.637 1.00 61.90 ? 219 THR B C 1 ATOM 4848 O O . THR B 1 221 ? -13.188 48.747 -25.814 1.00 62.04 ? 219 THR B O 1 ATOM 4849 C CB . THR B 1 221 ? -12.030 46.096 -24.941 1.00 57.23 ? 219 THR B CB 1 ATOM 4850 O OG1 . THR B 1 221 ? -13.351 45.612 -24.636 1.00 51.13 ? 219 THR B OG1 1 ATOM 4851 C CG2 . THR B 1 221 ? -10.942 45.062 -24.583 1.00 51.19 ? 219 THR B CG2 1 ATOM 4852 N N . GLY B 1 222 ? -13.636 48.949 -23.619 1.00 59.97 ? 220 GLY B N 1 ATOM 4853 C CA . GLY B 1 222 ? -14.740 49.881 -23.819 1.00 60.63 ? 220 GLY B CA 1 ATOM 4854 C C . GLY B 1 222 ? -14.255 51.312 -23.866 1.00 65.70 ? 220 GLY B C 1 ATOM 4855 O O . GLY B 1 222 ? -14.706 52.116 -24.690 1.00 64.84 ? 220 GLY B O 1 ATOM 4856 N N . ILE B 1 223 ? -13.316 51.618 -22.988 1.00 64.15 ? 221 ILE B N 1 ATOM 4857 C CA . ILE B 1 223 ? -12.758 52.946 -22.893 1.00 66.01 ? 221 ILE B CA 1 ATOM 4858 C C . ILE B 1 223 ? -11.773 53.225 -24.056 1.00 74.12 ? 221 ILE B C 1 ATOM 4859 O O . ILE B 1 223 ? -11.714 54.365 -24.513 1.00 74.22 ? 221 ILE B O 1 ATOM 4860 C CB . ILE B 1 223 ? -12.185 53.179 -21.466 1.00 69.02 ? 221 ILE B CB 1 ATOM 4861 C CG1 . ILE B 1 223 ? -12.352 54.632 -21.034 1.00 69.58 ? 221 ILE B CG1 1 ATOM 4862 C CG2 . ILE B 1 223 ? -10.757 52.681 -21.284 1.00 69.61 ? 221 ILE B CG2 1 ATOM 4863 C CD1 . ILE B 1 223 ? -13.822 55.062 -20.750 1.00 78.95 ? 221 ILE B CD1 1 ATOM 4864 N N . GLU B 1 224 ? -11.065 52.187 -24.582 1.00 72.55 ? 222 GLU B N 1 ATOM 4865 C CA . GLU B 1 224 ? -10.152 52.380 -25.715 1.00 72.82 ? 222 GLU B CA 1 ATOM 4866 C C . GLU B 1 224 ? -10.954 52.796 -26.940 1.00 79.52 ? 222 GLU B C 1 ATOM 4867 O O . GLU B 1 224 ? -10.535 53.694 -27.677 1.00 80.26 ? 222 GLU B O 1 ATOM 4868 C CB . GLU B 1 224 ? -9.272 51.145 -25.992 1.00 74.01 ? 222 GLU B CB 1 ATOM 4869 C CG . GLU B 1 224 ? -10.032 49.859 -26.264 1.00 85.25 ? 222 GLU B CG 1 ATOM 4870 C CD . GLU B 1 224 ? -9.285 48.766 -27.003 1.00 97.17 ? 222 GLU B CD 1 ATOM 4871 O OE1 . GLU B 1 224 ? -8.371 48.156 -26.402 1.00 92.08 ? 222 GLU B OE1 1 ATOM 4872 O OE2 . GLU B 1 224 ? -9.649 48.487 -28.168 1.00 80.86 ? 222 GLU B OE2 1 ATOM 4873 N N . ALA B 1 225 ? -12.152 52.196 -27.099 1.00 76.25 ? 223 ALA B N 1 ATOM 4874 C CA . ALA B 1 225 ? -13.083 52.500 -28.181 1.00 75.94 ? 223 ALA B CA 1 ATOM 4875 C C . ALA B 1 225 ? -13.619 53.932 -28.043 1.00 79.88 ? 223 ALA B C 1 ATOM 4876 O O . ALA B 1 225 ? -13.899 54.579 -29.054 1.00 80.53 ? 223 ALA B O 1 ATOM 4877 C CB . ALA B 1 225 ? -14.231 51.502 -28.173 1.00 76.55 ? 223 ALA B CB 1 ATOM 4878 N N . PHE B 1 226 ? -13.762 54.425 -26.797 1.00 75.50 ? 224 PHE B N 1 ATOM 4879 C CA . PHE B 1 226 ? -14.246 55.777 -26.552 1.00 75.14 ? 224 PHE B CA 1 ATOM 4880 C C . PHE B 1 226 ? -13.168 56.759 -26.972 1.00 80.67 ? 224 PHE B C 1 ATOM 4881 O O . PHE B 1 226 ? -13.414 57.588 -27.847 1.00 80.30 ? 224 PHE B O 1 ATOM 4882 C CB . PHE B 1 226 ? -14.689 55.986 -25.079 1.00 76.59 ? 224 PHE B CB 1 ATOM 4883 C CG . PHE B 1 226 ? -14.804 57.447 -24.709 1.00 77.98 ? 224 PHE B CG 1 ATOM 4884 C CD1 . PHE B 1 226 ? -15.841 58.232 -25.216 1.00 81.30 ? 224 PHE B CD1 1 ATOM 4885 C CD2 . PHE B 1 226 ? -13.830 58.061 -23.931 1.00 79.88 ? 224 PHE B CD2 1 ATOM 4886 C CE1 . PHE B 1 226 ? -15.908 59.600 -24.938 1.00 82.05 ? 224 PHE B CE1 1 ATOM 4887 C CE2 . PHE B 1 226 ? -13.892 59.431 -23.662 1.00 82.99 ? 224 PHE B CE2 1 ATOM 4888 C CZ . PHE B 1 226 ? -14.931 60.189 -24.164 1.00 81.22 ? 224 PHE B CZ 1 ATOM 4889 N N . GLU B 1 227 ? -11.961 56.618 -26.376 1.00 78.25 ? 225 GLU B N 1 ATOM 4890 C CA . GLU B 1 227 ? -10.760 57.424 -26.612 1.00 78.08 ? 225 GLU B CA 1 ATOM 4891 C C . GLU B 1 227 ? -10.409 57.526 -28.117 1.00 83.06 ? 225 GLU B C 1 ATOM 4892 O O . GLU B 1 227 ? -10.097 58.618 -28.600 1.00 83.04 ? 225 GLU B O 1 ATOM 4893 C CB . GLU B 1 227 ? -9.594 56.889 -25.760 1.00 79.00 ? 225 GLU B CB 1 ATOM 4894 C CG . GLU B 1 227 ? -9.829 57.080 -24.265 1.00 84.65 ? 225 GLU B CG 1 ATOM 4895 C CD . GLU B 1 227 ? -8.777 56.539 -23.315 1.00 100.13 ? 225 GLU B CD 1 ATOM 4896 O OE1 . GLU B 1 227 ? -7.935 55.722 -23.752 1.00 104.96 ? 225 GLU B OE1 1 ATOM 4897 O OE2 . GLU B 1 227 ? -8.811 56.913 -22.120 1.00 85.61 ? 225 GLU B OE2 1 ATOM 4898 N N . LEU B 1 228 ? -10.555 56.414 -28.860 1.00 79.66 ? 226 LEU B N 1 ATOM 4899 C CA . LEU B 1 228 ? -10.334 56.364 -30.304 1.00 80.13 ? 226 LEU B CA 1 ATOM 4900 C C . LEU B 1 228 ? -11.343 57.273 -31.040 1.00 84.79 ? 226 LEU B C 1 ATOM 4901 O O . LEU B 1 228 ? -10.934 58.080 -31.875 1.00 84.69 ? 226 LEU B O 1 ATOM 4902 C CB . LEU B 1 228 ? -10.455 54.915 -30.797 1.00 80.30 ? 226 LEU B CB 1 ATOM 4903 C CG . LEU B 1 228 ? -10.321 54.703 -32.294 1.00 84.90 ? 226 LEU B CG 1 ATOM 4904 C CD1 . LEU B 1 228 ? -8.938 55.112 -32.774 1.00 84.91 ? 226 LEU B CD1 1 ATOM 4905 C CD2 . LEU B 1 228 ? -10.634 53.265 -32.673 1.00 87.07 ? 226 LEU B CD2 1 ATOM 4906 N N . GLU B 1 229 ? -12.652 57.149 -30.710 1.00 81.38 ? 227 GLU B N 1 ATOM 4907 C CA . GLU B 1 229 ? -13.750 57.945 -31.285 1.00 80.65 ? 227 GLU B CA 1 ATOM 4908 C C . GLU B 1 229 ? -13.666 59.427 -30.839 1.00 84.89 ? 227 GLU B C 1 ATOM 4909 O O . GLU B 1 229 ? -14.133 60.332 -31.555 1.00 83.35 ? 227 GLU B O 1 ATOM 4910 C CB . GLU B 1 229 ? -15.108 57.341 -30.885 1.00 81.48 ? 227 GLU B CB 1 ATOM 4911 C CG . GLU B 1 229 ? -15.461 56.059 -31.623 1.00 89.61 ? 227 GLU B CG 1 ATOM 4912 C CD . GLU B 1 229 ? -15.782 56.166 -33.105 1.00 108.68 ? 227 GLU B CD 1 ATOM 4913 O OE1 . GLU B 1 229 ? -16.224 57.247 -33.559 1.00 93.48 ? 227 GLU B OE1 1 ATOM 4914 O OE2 . GLU B 1 229 ? -15.639 55.139 -33.806 1.00 105.19 ? 227 GLU B OE2 1 ATOM 4915 N N . ALA B 1 230 ? -13.068 59.652 -29.643 1.00 81.68 ? 228 ALA B N 1 ATOM 4916 C CA . ALA B 1 230 ? -12.868 60.957 -29.031 1.00 81.59 ? 228 ALA B CA 1 ATOM 4917 C C . ALA B 1 230 ? -11.821 61.719 -29.828 1.00 86.30 ? 228 ALA B C 1 ATOM 4918 O O . ALA B 1 230 ? -12.117 62.816 -30.328 1.00 85.95 ? 228 ALA B O 1 ATOM 4919 C CB . ALA B 1 230 ? -12.430 60.798 -27.582 1.00 82.20 ? 228 ALA B CB 1 ATOM 4920 N N . ARG B 1 231 ? -10.620 61.100 -30.005 1.00 82.79 ? 229 ARG B N 1 ATOM 4921 C CA . ARG B 1 231 ? -9.488 61.647 -30.758 1.00 82.26 ? 229 ARG B CA 1 ATOM 4922 C C . ARG B 1 231 ? -9.893 62.032 -32.190 1.00 84.33 ? 229 ARG B C 1 ATOM 4923 O O . ARG B 1 231 ? -9.520 63.105 -32.664 1.00 84.37 ? 229 ARG B O 1 ATOM 4924 C CB . ARG B 1 231 ? -8.292 60.680 -30.738 1.00 84.52 ? 229 ARG B CB 1 ATOM 4925 C CG . ARG B 1 231 ? -7.647 60.528 -29.358 1.00 100.43 ? 229 ARG B CG 1 ATOM 4926 C CD . ARG B 1 231 ? -6.228 59.989 -29.427 1.00 117.93 ? 229 ARG B CD 1 ATOM 4927 N NE . ARG B 1 231 ? -5.251 61.062 -29.643 1.00 133.64 ? 229 ARG B NE 1 ATOM 4928 C CZ . ARG B 1 231 ? -3.930 60.894 -29.671 1.00 149.45 ? 229 ARG B CZ 1 ATOM 4929 N NH1 . ARG B 1 231 ? -3.403 59.687 -29.500 1.00 137.36 ? 229 ARG B NH1 1 ATOM 4930 N NH2 . ARG B 1 231 ? -3.127 61.932 -29.871 1.00 135.08 ? 229 ARG B NH2 1 ATOM 4931 N N . ALA B 1 232 ? -10.731 61.208 -32.833 1.00 79.63 ? 230 ALA B N 1 ATOM 4932 C CA . ALA B 1 232 ? -11.265 61.451 -34.180 1.00 79.19 ? 230 ALA B CA 1 ATOM 4933 C C . ALA B 1 232 ? -12.181 62.700 -34.254 1.00 82.42 ? 230 ALA B C 1 ATOM 4934 O O . ALA B 1 232 ? -12.394 63.249 -35.335 1.00 80.66 ? 230 ALA B O 1 ATOM 4935 C CB . ALA B 1 232 ? -12.024 60.221 -34.659 1.00 79.75 ? 230 ALA B CB 1 ATOM 4936 N N . ARG B 1 233 ? -12.712 63.137 -33.102 1.00 80.28 ? 231 ARG B N 1 ATOM 4937 C CA . ARG B 1 233 ? -13.630 64.269 -32.987 1.00 80.76 ? 231 ARG B CA 1 ATOM 4938 C C . ARG B 1 233 ? -12.975 65.526 -32.396 1.00 85.49 ? 231 ARG B C 1 ATOM 4939 O O . ARG B 1 233 ? -13.655 66.544 -32.199 1.00 84.15 ? 231 ARG B O 1 ATOM 4940 C CB . ARG B 1 233 ? -14.844 63.842 -32.154 1.00 80.79 ? 231 ARG B CB 1 ATOM 4941 C CG . ARG B 1 233 ? -15.941 63.248 -33.013 1.00 82.95 ? 231 ARG B CG 1 ATOM 4942 C CD . ARG B 1 233 ? -17.068 62.647 -32.195 1.00 75.89 ? 231 ARG B CD 1 ATOM 4943 N NE . ARG B 1 233 ? -17.992 61.916 -33.060 1.00 69.46 ? 231 ARG B NE 1 ATOM 4944 C CZ . ARG B 1 233 ? -17.803 60.662 -33.463 1.00 75.36 ? 231 ARG B CZ 1 ATOM 4945 N NH1 . ARG B 1 233 ? -16.730 59.985 -33.070 1.00 51.09 ? 231 ARG B NH1 1 ATOM 4946 N NH2 . ARG B 1 233 ? -18.684 60.077 -34.264 1.00 63.48 ? 231 ARG B NH2 1 ATOM 4947 N N . ASN B 1 234 ? -11.636 65.453 -32.165 1.00 82.83 ? 232 ASN B N 1 ATOM 4948 C CA . ASN B 1 234 ? -10.772 66.477 -31.554 1.00 82.37 ? 232 ASN B CA 1 ATOM 4949 C C . ASN B 1 234 ? -11.135 66.633 -30.076 1.00 84.25 ? 232 ASN B C 1 ATOM 4950 O O . ASN B 1 234 ? -11.365 67.741 -29.598 1.00 83.70 ? 232 ASN B O 1 ATOM 4951 C CB . ASN B 1 234 ? -10.770 67.832 -32.322 1.00 84.72 ? 232 ASN B CB 1 ATOM 4952 C CG . ASN B 1 234 ? -10.481 67.746 -33.807 1.00 107.21 ? 232 ASN B CG 1 ATOM 4953 O OD1 . ASN B 1 234 ? -9.545 67.059 -34.255 1.00 103.33 ? 232 ASN B OD1 1 ATOM 4954 N ND2 . ASN B 1 234 ? -11.264 68.484 -34.600 1.00 94.24 ? 232 ASN B ND2 1 ATOM 4955 N N . ILE B 1 235 ? -11.232 65.499 -29.368 1.00 80.46 ? 233 ILE B N 1 ATOM 4956 C CA . ILE B 1 235 ? -11.538 65.458 -27.935 1.00 80.59 ? 233 ILE B CA 1 ATOM 4957 C C . ILE B 1 235 ? -10.318 64.907 -27.201 1.00 85.46 ? 233 ILE B C 1 ATOM 4958 O O . ILE B 1 235 ? -9.839 63.816 -27.521 1.00 86.03 ? 233 ILE B O 1 ATOM 4959 C CB . ILE B 1 235 ? -12.898 64.762 -27.589 1.00 83.28 ? 233 ILE B CB 1 ATOM 4960 C CG1 . ILE B 1 235 ? -14.068 65.733 -27.876 1.00 84.01 ? 233 ILE B CG1 1 ATOM 4961 C CG2 . ILE B 1 235 ? -12.953 64.303 -26.126 1.00 82.73 ? 233 ILE B CG2 1 ATOM 4962 C CD1 . ILE B 1 235 ? -15.415 65.120 -28.179 1.00 92.27 ? 233 ILE B CD1 1 ATOM 4963 N N . SER B 1 236 ? -9.789 65.709 -26.268 1.00 81.19 ? 234 SER B N 1 ATOM 4964 C CA . SER B 1 236 ? -8.608 65.432 -25.463 1.00 81.15 ? 234 SER B CA 1 ATOM 4965 C C . SER B 1 236 ? -8.947 64.615 -24.217 1.00 84.73 ? 234 SER B C 1 ATOM 4966 O O . SER B 1 236 ? -10.065 64.702 -23.709 1.00 84.34 ? 234 SER B O 1 ATOM 4967 C CB . SER B 1 236 ? -7.938 66.742 -25.047 1.00 85.30 ? 234 SER B CB 1 ATOM 4968 O OG . SER B 1 236 ? -7.422 67.472 -26.150 1.00 95.36 ? 234 SER B OG 1 ATOM 4969 N N . VAL B 1 237 ? -7.967 63.847 -23.714 1.00 81.06 ? 235 VAL B N 1 ATOM 4970 C CA . VAL B 1 237 ? -8.109 63.055 -22.502 1.00 81.07 ? 235 VAL B CA 1 ATOM 4971 C C . VAL B 1 237 ? -7.089 63.534 -21.461 1.00 85.89 ? 235 VAL B C 1 ATOM 4972 O O . VAL B 1 237 ? -5.901 63.631 -21.758 1.00 86.00 ? 235 VAL B O 1 ATOM 4973 C CB . VAL B 1 237 ? -8.118 61.513 -22.747 1.00 85.29 ? 235 VAL B CB 1 ATOM 4974 C CG1 . VAL B 1 237 ? -6.888 61.043 -23.522 1.00 85.60 ? 235 VAL B CG1 1 ATOM 4975 C CG2 . VAL B 1 237 ? -8.287 60.727 -21.447 1.00 85.03 ? 235 VAL B CG2 1 ATOM 4976 N N . ALA B 1 238 ? -7.578 63.870 -20.255 1.00 83.36 ? 236 ALA B N 1 ATOM 4977 C CA . ALA B 1 238 ? -6.809 64.367 -19.105 1.00 83.25 ? 236 ALA B CA 1 ATOM 4978 C C . ALA B 1 238 ? -6.058 63.234 -18.393 1.00 87.06 ? 236 ALA B C 1 ATOM 4979 O O . ALA B 1 238 ? -4.826 63.226 -18.346 1.00 86.25 ? 236 ALA B O 1 ATOM 4980 C CB . ALA B 1 238 ? -7.754 65.052 -18.131 1.00 84.03 ? 236 ALA B CB 1 ATOM 4981 N N . THR B 1 239 ? -6.822 62.290 -17.828 1.00 83.64 ? 237 THR B N 1 ATOM 4982 C CA . THR B 1 239 ? -6.331 61.096 -17.153 1.00 83.06 ? 237 THR B CA 1 ATOM 4983 C C . THR B 1 239 ? -7.186 59.890 -17.595 1.00 85.28 ? 237 THR B C 1 ATOM 4984 O O . THR B 1 239 ? -8.344 60.058 -18.000 1.00 84.61 ? 237 THR B O 1 ATOM 4985 C CB . THR B 1 239 ? -6.220 61.298 -15.623 1.00 92.30 ? 237 THR B CB 1 ATOM 4986 O OG1 . THR B 1 239 ? -5.611 60.141 -15.038 1.00 91.18 ? 237 THR B OG1 1 ATOM 4987 C CG2 . THR B 1 239 ? -7.572 61.574 -14.949 1.00 92.03 ? 237 THR B CG2 1 ATOM 4988 N N . SER B 1 240 ? -6.586 58.690 -17.551 1.00 79.64 ? 238 SER B N 1 ATOM 4989 C CA . SER B 1 240 ? -7.218 57.435 -17.913 1.00 78.49 ? 238 SER B CA 1 ATOM 4990 C C . SER B 1 240 ? -7.008 56.497 -16.750 1.00 81.82 ? 238 SER B C 1 ATOM 4991 O O . SER B 1 240 ? -5.895 56.026 -16.525 1.00 81.83 ? 238 SER B O 1 ATOM 4992 C CB . SER B 1 240 ? -6.633 56.891 -19.214 1.00 81.45 ? 238 SER B CB 1 ATOM 4993 O OG . SER B 1 240 ? -6.916 57.760 -20.299 1.00 87.52 ? 238 SER B OG 1 ATOM 4994 N N . GLU B 1 241 ? -8.065 56.295 -15.952 1.00 78.10 ? 239 GLU B N 1 ATOM 4995 C CA . GLU B 1 241 ? -8.003 55.511 -14.728 1.00 77.35 ? 239 GLU B CA 1 ATOM 4996 C C . GLU B 1 241 ? -8.529 54.080 -14.860 1.00 79.48 ? 239 GLU B C 1 ATOM 4997 O O . GLU B 1 241 ? -9.304 53.789 -15.768 1.00 77.51 ? 239 GLU B O 1 ATOM 4998 C CB . GLU B 1 241 ? -8.701 56.265 -13.599 1.00 78.76 ? 239 GLU B CB 1 ATOM 4999 C CG . GLU B 1 241 ? -7.944 57.514 -13.166 1.00 92.71 ? 239 GLU B CG 1 ATOM 5000 C CD . GLU B 1 241 ? -6.527 57.335 -12.643 1.00 118.19 ? 239 GLU B CD 1 ATOM 5001 O OE1 . GLU B 1 241 ? -6.278 56.354 -11.901 1.00 118.77 ? 239 GLU B OE1 1 ATOM 5002 O OE2 . GLU B 1 241 ? -5.672 58.197 -12.954 1.00 106.25 ? 239 GLU B OE2 1 ATOM 5003 N N . LYS B 1 242 ? -8.058 53.189 -13.957 1.00 76.54 ? 240 LYS B N 1 ATOM 5004 C CA . LYS B 1 242 ? -8.380 51.761 -13.892 1.00 77.03 ? 240 LYS B CA 1 ATOM 5005 C C . LYS B 1 242 ? -8.960 51.418 -12.506 1.00 84.95 ? 240 LYS B C 1 ATOM 5006 O O . LYS B 1 242 ? -8.410 51.867 -11.497 1.00 85.42 ? 240 LYS B O 1 ATOM 5007 C CB . LYS B 1 242 ? -7.104 50.939 -14.170 1.00 78.64 ? 240 LYS B CB 1 ATOM 5008 C CG . LYS B 1 242 ? -7.312 49.516 -14.679 1.00 82.55 ? 240 LYS B CG 1 ATOM 5009 C CD . LYS B 1 242 ? -6.030 48.692 -14.490 1.00 86.22 ? 240 LYS B CD 1 ATOM 5010 C CE . LYS B 1 242 ? -6.102 47.299 -15.079 1.00 88.63 ? 240 LYS B CE 1 ATOM 5011 N NZ . LYS B 1 242 ? -5.458 47.229 -16.420 1.00 89.16 ? 240 LYS B NZ 1 ATOM 5012 N N . VAL B 1 243 ? -10.073 50.640 -12.455 1.00 83.75 ? 241 VAL B N 1 ATOM 5013 C CA . VAL B 1 243 ? -10.729 50.246 -11.198 1.00 84.99 ? 241 VAL B CA 1 ATOM 5014 C C . VAL B 1 243 ? -11.057 48.731 -11.119 1.00 93.37 ? 241 VAL B C 1 ATOM 5015 O O . VAL B 1 243 ? -11.560 48.152 -12.080 1.00 92.85 ? 241 VAL B O 1 ATOM 5016 C CB . VAL B 1 243 ? -11.980 51.107 -10.847 1.00 88.64 ? 241 VAL B CB 1 ATOM 5017 C CG1 . VAL B 1 243 ? -11.594 52.525 -10.450 1.00 88.37 ? 241 VAL B CG1 1 ATOM 5018 C CG2 . VAL B 1 243 ? -13.007 51.125 -11.971 1.00 88.47 ? 241 VAL B CG2 1 ATOM 5019 N N . GLY B 1 244 ? -10.786 48.127 -9.960 1.00 93.09 ? 242 GLY B N 1 ATOM 5020 C CA . GLY B 1 244 ? -11.083 46.723 -9.679 1.00 94.16 ? 242 GLY B CA 1 ATOM 5021 C C . GLY B 1 244 ? -12.163 46.568 -8.620 1.00 101.32 ? 242 GLY B C 1 ATOM 5022 O O . GLY B 1 244 ? -12.595 47.563 -8.033 1.00 101.47 ? 242 GLY B O 1 ATOM 5023 N N . ARG B 1 245 ? -12.617 45.321 -8.365 1.00 99.98 ? 243 ARG B N 1 ATOM 5024 C CA . ARG B 1 245 ? -13.637 44.986 -7.344 1.00 100.38 ? 243 ARG B CA 1 ATOM 5025 C C . ARG B 1 245 ? -12.952 44.833 -5.976 1.00 103.70 ? 243 ARG B C 1 ATOM 5026 O O . ARG B 1 245 ? -13.529 45.211 -4.948 1.00 102.75 ? 243 ARG B O 1 ATOM 5027 C CB . ARG B 1 245 ? -14.369 43.679 -7.718 1.00 102.68 ? 243 ARG B CB 1 ATOM 5028 C CG . ARG B 1 245 ? -15.506 43.268 -6.778 1.00 113.43 ? 243 ARG B CG 1 ATOM 5029 C CD . ARG B 1 245 ? -15.697 41.763 -6.771 1.00 118.30 ? 243 ARG B CD 1 ATOM 5030 N NE . ARG B 1 245 ? -16.841 41.371 -5.946 1.00 121.02 ? 243 ARG B NE 1 ATOM 5031 C CZ . ARG B 1 245 ? -16.752 40.839 -4.731 1.00 128.55 ? 243 ARG B CZ 1 ATOM 5032 N NH1 . ARG B 1 245 ? -15.564 40.609 -4.184 1.00 111.82 ? 243 ARG B NH1 1 ATOM 5033 N NH2 . ARG B 1 245 ? -17.851 40.521 -4.058 1.00 112.23 ? 243 ARG B NH2 1 ATOM 5034 N N . ALA B 1 246 ? -11.712 44.274 -5.985 1.00 99.86 ? 244 ALA B N 1 ATOM 5035 C CA . ALA B 1 246 ? -10.854 44.067 -4.813 1.00 98.78 ? 244 ALA B CA 1 ATOM 5036 C C . ALA B 1 246 ? -10.543 45.417 -4.126 1.00 100.76 ? 244 ALA B C 1 ATOM 5037 O O . ALA B 1 246 ? -10.397 45.456 -2.896 1.00 100.33 ? 244 ALA B O 1 ATOM 5038 C CB . ALA B 1 246 ? -9.567 43.367 -5.230 1.00 99.24 ? 244 ALA B CB 1 ATOM 5039 N N . MET B 1 247 ? -10.497 46.518 -4.937 1.00 95.16 ? 245 MET B N 1 ATOM 5040 C CA . MET B 1 247 ? -10.255 47.915 -4.553 1.00 94.36 ? 245 MET B CA 1 ATOM 5041 C C . MET B 1 247 ? -11.139 48.327 -3.384 1.00 98.18 ? 245 MET B C 1 ATOM 5042 O O . MET B 1 247 ? -12.357 48.135 -3.445 1.00 98.36 ? 245 MET B O 1 ATOM 5043 C CB . MET B 1 247 ? -10.563 48.849 -5.738 1.00 96.50 ? 245 MET B CB 1 ATOM 5044 C CG . MET B 1 247 ? -9.353 49.450 -6.405 1.00 99.87 ? 245 MET B CG 1 ATOM 5045 S SD . MET B 1 247 ? -9.858 50.831 -7.469 1.00 103.71 ? 245 MET B SD 1 ATOM 5046 C CE . MET B 1 247 ? -8.314 51.283 -8.176 1.00 100.29 ? 245 MET B CE 1 ATOM 5047 N N . SER B 1 248 ? -10.532 48.892 -2.325 1.00 94.05 ? 246 SER B N 1 ATOM 5048 C CA . SER B 1 248 ? -11.261 49.356 -1.143 1.00 93.58 ? 246 SER B CA 1 ATOM 5049 C C . SER B 1 248 ? -11.533 50.869 -1.172 1.00 95.63 ? 246 SER B C 1 ATOM 5050 O O . SER B 1 248 ? -11.054 51.566 -2.075 1.00 94.22 ? 246 SER B O 1 ATOM 5051 C CB . SER B 1 248 ? -10.561 48.926 0.146 1.00 97.91 ? 246 SER B CB 1 ATOM 5052 O OG . SER B 1 248 ? -11.009 47.653 0.589 1.00 106.41 ? 246 SER B OG 1 ATOM 5053 N N . ARG B 1 249 ? -12.338 51.356 -0.192 1.00 91.65 ? 247 ARG B N 1 ATOM 5054 C CA . ARG B 1 249 ? -12.778 52.748 -0.025 1.00 91.01 ? 247 ARG B CA 1 ATOM 5055 C C . ARG B 1 249 ? -11.673 53.785 -0.292 1.00 92.56 ? 247 ARG B C 1 ATOM 5056 O O . ARG B 1 249 ? -11.896 54.729 -1.056 1.00 91.12 ? 247 ARG B O 1 ATOM 5057 C CB . ARG B 1 249 ? -13.413 52.947 1.363 1.00 92.02 ? 247 ARG B CB 1 ATOM 5058 N N . ALA B 1 250 ? -10.478 53.565 0.304 1.00 88.39 ? 248 ALA B N 1 ATOM 5059 C CA . ALA B 1 250 ? -9.272 54.395 0.188 1.00 87.48 ? 248 ALA B CA 1 ATOM 5060 C C . ALA B 1 250 ? -8.787 54.512 -1.260 1.00 89.08 ? 248 ALA B C 1 ATOM 5061 O O . ALA B 1 250 ? -8.506 55.623 -1.727 1.00 88.06 ? 248 ALA B O 1 ATOM 5062 C CB . ALA B 1 250 ? -8.165 53.815 1.059 1.00 88.21 ? 248 ALA B CB 1 ATOM 5063 N N . ALA B 1 251 ? -8.711 53.357 -1.966 1.00 84.45 ? 249 ALA B N 1 ATOM 5064 C CA . ALA B 1 251 ? -8.279 53.253 -3.358 1.00 83.45 ? 249 ALA B CA 1 ATOM 5065 C C . ALA B 1 251 ? -9.240 53.971 -4.305 1.00 87.22 ? 249 ALA B C 1 ATOM 5066 O O . ALA B 1 251 ? -8.793 54.537 -5.301 1.00 87.02 ? 249 ALA B O 1 ATOM 5067 C CB . ALA B 1 251 ? -8.126 51.794 -3.756 1.00 83.96 ? 249 ALA B CB 1 ATOM 5068 N N . PHE B 1 252 ? -10.549 53.967 -3.994 1.00 83.43 ? 250 PHE B N 1 ATOM 5069 C CA . PHE B 1 252 ? -11.531 54.652 -4.820 1.00 83.53 ? 250 PHE B CA 1 ATOM 5070 C C . PHE B 1 252 ? -11.400 56.168 -4.683 1.00 88.46 ? 250 PHE B C 1 ATOM 5071 O O . PHE B 1 252 ? -11.597 56.893 -5.665 1.00 88.59 ? 250 PHE B O 1 ATOM 5072 C CB . PHE B 1 252 ? -12.961 54.175 -4.515 1.00 85.37 ? 250 PHE B CB 1 ATOM 5073 C CG . PHE B 1 252 ? -13.425 53.060 -5.420 1.00 86.84 ? 250 PHE B CG 1 ATOM 5074 C CD1 . PHE B 1 252 ? -13.889 53.331 -6.703 1.00 90.26 ? 250 PHE B CD1 1 ATOM 5075 C CD2 . PHE B 1 252 ? -13.386 51.738 -4.996 1.00 88.50 ? 250 PHE B CD2 1 ATOM 5076 C CE1 . PHE B 1 252 ? -14.285 52.293 -7.555 1.00 91.04 ? 250 PHE B CE1 1 ATOM 5077 C CE2 . PHE B 1 252 ? -13.778 50.703 -5.847 1.00 91.25 ? 250 PHE B CE2 1 ATOM 5078 C CZ . PHE B 1 252 ? -14.227 50.987 -7.120 1.00 89.68 ? 250 PHE B CZ 1 ATOM 5079 N N . GLU B 1 253 ? -11.040 56.639 -3.470 1.00 84.66 ? 251 GLU B N 1 ATOM 5080 C CA . GLU B 1 253 ? -10.843 58.060 -3.162 1.00 83.99 ? 251 GLU B CA 1 ATOM 5081 C C . GLU B 1 253 ? -9.659 58.613 -3.954 1.00 85.99 ? 251 GLU B C 1 ATOM 5082 O O . GLU B 1 253 ? -9.717 59.747 -4.438 1.00 84.04 ? 251 GLU B O 1 ATOM 5083 C CB . GLU B 1 253 ? -10.652 58.276 -1.653 1.00 85.24 ? 251 GLU B CB 1 ATOM 5084 C CG . GLU B 1 253 ? -11.934 58.119 -0.859 1.00 94.19 ? 251 GLU B CG 1 ATOM 5085 C CD . GLU B 1 253 ? -11.811 58.489 0.603 1.00 118.82 ? 251 GLU B CD 1 ATOM 5086 O OE1 . GLU B 1 253 ? -11.625 57.572 1.437 1.00 117.96 ? 251 GLU B OE1 1 ATOM 5087 O OE2 . GLU B 1 253 ? -11.905 59.698 0.916 1.00 113.78 ? 251 GLU B OE2 1 ATOM 5088 N N . GLY B 1 254 ? -8.633 57.775 -4.118 1.00 82.56 ? 252 GLY B N 1 ATOM 5089 C CA . GLY B 1 254 ? -7.434 58.091 -4.881 1.00 82.89 ? 252 GLY B CA 1 ATOM 5090 C C . GLY B 1 254 ? -7.713 58.346 -6.349 1.00 88.05 ? 252 GLY B C 1 ATOM 5091 O O . GLY B 1 254 ? -7.027 59.167 -6.969 1.00 88.42 ? 252 GLY B O 1 ATOM 5092 N N . VAL B 1 255 ? -8.740 57.650 -6.909 1.00 84.11 ? 253 VAL B N 1 ATOM 5093 C CA . VAL B 1 255 ? -9.173 57.774 -8.307 1.00 83.81 ? 253 VAL B CA 1 ATOM 5094 C C . VAL B 1 255 ? -9.780 59.163 -8.527 1.00 88.65 ? 253 VAL B C 1 ATOM 5095 O O . VAL B 1 255 ? -9.437 59.844 -9.496 1.00 88.50 ? 253 VAL B O 1 ATOM 5096 C CB . VAL B 1 255 ? -10.145 56.643 -8.745 1.00 87.42 ? 253 VAL B CB 1 ATOM 5097 C CG1 . VAL B 1 255 ? -10.388 56.678 -10.256 1.00 87.15 ? 253 VAL B CG1 1 ATOM 5098 C CG2 . VAL B 1 255 ? -9.625 55.271 -8.329 1.00 87.17 ? 253 VAL B CG2 1 ATOM 5099 N N . VAL B 1 256 ? -10.673 59.568 -7.611 1.00 85.55 ? 254 VAL B N 1 ATOM 5100 C CA . VAL B 1 256 ? -11.356 60.862 -7.569 1.00 85.67 ? 254 VAL B CA 1 ATOM 5101 C C . VAL B 1 256 ? -10.291 61.950 -7.409 1.00 89.68 ? 254 VAL B C 1 ATOM 5102 O O . VAL B 1 256 ? -10.346 62.960 -8.113 1.00 88.28 ? 254 VAL B O 1 ATOM 5103 C CB . VAL B 1 256 ? -12.382 60.884 -6.403 1.00 90.16 ? 254 VAL B CB 1 ATOM 5104 C CG1 . VAL B 1 256 ? -13.137 62.205 -6.347 1.00 89.93 ? 254 VAL B CG1 1 ATOM 5105 C CG2 . VAL B 1 256 ? -13.358 59.717 -6.510 1.00 90.32 ? 254 VAL B CG2 1 ATOM 5106 N N . ARG B 1 257 ? -9.304 61.712 -6.495 1.00 87.25 ? 255 ARG B N 1 ATOM 5107 C CA . ARG B 1 257 ? -8.161 62.588 -6.228 1.00 86.95 ? 255 ARG B CA 1 ATOM 5108 C C . ARG B 1 257 ? -7.422 62.794 -7.540 1.00 90.23 ? 255 ARG B C 1 ATOM 5109 O O . ARG B 1 257 ? -7.237 63.938 -7.958 1.00 89.39 ? 255 ARG B O 1 ATOM 5110 C CB . ARG B 1 257 ? -7.211 61.962 -5.182 1.00 86.90 ? 255 ARG B CB 1 ATOM 5111 C CG . ARG B 1 257 ? -7.599 62.228 -3.729 1.00 95.22 ? 255 ARG B CG 1 ATOM 5112 C CD . ARG B 1 257 ? -6.571 61.673 -2.758 1.00 98.49 ? 255 ARG B CD 1 ATOM 5113 N NE . ARG B 1 257 ? -7.162 61.353 -1.454 1.00 106.47 ? 255 ARG B NE 1 ATOM 5114 C CZ . ARG B 1 257 ? -7.214 60.130 -0.925 1.00 119.56 ? 255 ARG B CZ 1 ATOM 5115 N NH1 . ARG B 1 257 ? -6.698 59.092 -1.577 1.00 103.67 ? 255 ARG B NH1 1 ATOM 5116 N NH2 . ARG B 1 257 ? -7.771 59.938 0.265 1.00 103.44 ? 255 ARG B NH2 1 ATOM 5117 N N . ALA B 1 258 ? -7.086 61.670 -8.224 1.00 86.59 ? 256 ALA B N 1 ATOM 5118 C CA . ALA B 1 258 ? -6.388 61.638 -9.513 1.00 86.23 ? 256 ALA B CA 1 ATOM 5119 C C . ALA B 1 258 ? -7.134 62.394 -10.619 1.00 89.32 ? 256 ALA B C 1 ATOM 5120 O O . ALA B 1 258 ? -6.495 63.045 -11.441 1.00 88.99 ? 256 ALA B O 1 ATOM 5121 C CB . ALA B 1 258 ? -6.111 60.202 -9.936 1.00 86.78 ? 256 ALA B CB 1 ATOM 5122 N N . LEU B 1 259 ? -8.474 62.345 -10.614 1.00 85.57 ? 257 LEU B N 1 ATOM 5123 C CA . LEU B 1 259 ? -9.310 63.031 -11.611 1.00 85.34 ? 257 LEU B CA 1 ATOM 5124 C C . LEU B 1 259 ? -9.344 64.564 -11.401 1.00 89.41 ? 257 LEU B C 1 ATOM 5125 O O . LEU B 1 259 ? -9.731 65.318 -12.306 1.00 88.86 ? 257 LEU B O 1 ATOM 5126 C CB . LEU B 1 259 ? -10.732 62.427 -11.628 1.00 84.97 ? 257 LEU B CB 1 ATOM 5127 C CG . LEU B 1 259 ? -11.067 61.470 -12.777 1.00 88.77 ? 257 LEU B CG 1 ATOM 5128 C CD1 . LEU B 1 259 ? -10.543 60.079 -12.508 1.00 88.50 ? 257 LEU B CD1 1 ATOM 5129 C CD2 . LEU B 1 259 ? -12.570 61.370 -12.968 1.00 91.31 ? 257 LEU B CD2 1 ATOM 5130 N N . LEU B 1 260 ? -8.912 65.013 -10.212 1.00 85.75 ? 258 LEU B N 1 ATOM 5131 C CA . LEU B 1 260 ? -8.860 66.428 -9.865 1.00 85.12 ? 258 LEU B CA 1 ATOM 5132 C C . LEU B 1 260 ? -7.552 67.091 -10.314 1.00 87.91 ? 258 LEU B C 1 ATOM 5133 O O . LEU B 1 260 ? -7.568 68.281 -10.609 1.00 85.94 ? 258 LEU B O 1 ATOM 5134 C CB . LEU B 1 260 ? -9.116 66.630 -8.360 1.00 84.95 ? 258 LEU B CB 1 ATOM 5135 C CG . LEU B 1 260 ? -10.527 66.283 -7.866 1.00 88.72 ? 258 LEU B CG 1 ATOM 5136 C CD1 . LEU B 1 260 ? -10.525 65.978 -6.401 1.00 88.62 ? 258 LEU B CD1 1 ATOM 5137 C CD2 . LEU B 1 260 ? -11.512 67.391 -8.160 1.00 90.42 ? 258 LEU B CD2 1 ATOM 5138 N N . GLN B 1 261 ? -6.443 66.303 -10.416 1.00 86.25 ? 259 GLN B N 1 ATOM 5139 C CA . GLN B 1 261 ? -5.087 66.719 -10.838 1.00 87.12 ? 259 GLN B CA 1 ATOM 5140 C C . GLN B 1 261 ? -5.119 67.539 -12.127 1.00 94.76 ? 259 GLN B C 1 ATOM 5141 O O . GLN B 1 261 ? -4.295 68.438 -12.327 1.00 94.60 ? 259 GLN B O 1 ATOM 5142 C CB . GLN B 1 261 ? -4.146 65.510 -11.014 1.00 88.28 ? 259 GLN B CB 1 ATOM 5143 C CG . GLN B 1 261 ? -4.025 64.577 -9.807 1.00 106.70 ? 259 GLN B CG 1 ATOM 5144 C CD . GLN B 1 261 ? -3.621 65.256 -8.523 1.00 125.29 ? 259 GLN B CD 1 ATOM 5145 O OE1 . GLN B 1 261 ? -4.442 65.461 -7.620 1.00 118.01 ? 259 GLN B OE1 1 ATOM 5146 N NE2 . GLN B 1 261 ? -2.344 65.596 -8.406 1.00 120.22 ? 259 GLN B NE2 1 ATOM 5147 N N . LYS B 1 262 ? -6.077 67.213 -13.000 1.00 93.42 ? 260 LYS B N 1 ATOM 5148 C CA . LYS B 1 262 ? -6.350 67.939 -14.227 1.00 93.91 ? 260 LYS B CA 1 ATOM 5149 C C . LYS B 1 262 ? -7.781 68.495 -14.051 1.00 99.84 ? 260 LYS B C 1 ATOM 5150 O O . LYS B 1 262 ? -8.770 67.800 -14.319 1.00 99.37 ? 260 LYS B O 1 ATOM 5151 C CB . LYS B 1 262 ? -6.118 67.054 -15.454 1.00 95.69 ? 260 LYS B CB 1 ATOM 5152 C CG . LYS B 1 262 ? -4.657 67.127 -15.891 1.00 102.49 ? 260 LYS B CG 1 ATOM 5153 C CD . LYS B 1 262 ? -4.175 65.912 -16.637 1.00 105.44 ? 260 LYS B CD 1 ATOM 5154 C CE . LYS B 1 262 ? -2.912 66.218 -17.404 1.00 105.72 ? 260 LYS B CE 1 ATOM 5155 N NZ . LYS B 1 262 ? -2.388 65.011 -18.091 1.00 110.19 ? 260 LYS B NZ 1 ATOM 5156 N N . PRO B 1 263 ? -7.887 69.697 -13.416 1.00 97.36 ? 261 PRO B N 1 ATOM 5157 C CA . PRO B 1 263 ? -9.216 70.243 -13.087 1.00 97.07 ? 261 PRO B CA 1 ATOM 5158 C C . PRO B 1 263 ? -9.939 70.920 -14.240 1.00 100.12 ? 261 PRO B C 1 ATOM 5159 O O . PRO B 1 263 ? -11.121 71.267 -14.100 1.00 99.00 ? 261 PRO B O 1 ATOM 5160 C CB . PRO B 1 263 ? -8.940 71.203 -11.921 1.00 98.88 ? 261 PRO B CB 1 ATOM 5161 C CG . PRO B 1 263 ? -7.434 71.342 -11.837 1.00 103.40 ? 261 PRO B CG 1 ATOM 5162 C CD . PRO B 1 263 ? -6.816 70.617 -12.986 1.00 98.93 ? 261 PRO B CD 1 ATOM 5163 N N . SER B 1 264 ? -9.245 71.077 -15.391 1.00 96.40 ? 262 SER B N 1 ATOM 5164 C CA . SER B 1 264 ? -9.821 71.652 -16.607 1.00 95.75 ? 262 SER B CA 1 ATOM 5165 C C . SER B 1 264 ? -10.834 70.649 -17.205 1.00 97.75 ? 262 SER B C 1 ATOM 5166 O O . SER B 1 264 ? -11.696 71.035 -18.005 1.00 97.36 ? 262 SER B O 1 ATOM 5167 C CB . SER B 1 264 ? -8.722 72.010 -17.602 1.00 99.07 ? 262 SER B CB 1 ATOM 5168 N N . ALA B 1 265 ? -10.732 69.363 -16.771 1.00 92.17 ? 263 ALA B N 1 ATOM 5169 C CA . ALA B 1 265 ? -11.616 68.256 -17.134 1.00 90.51 ? 263 ALA B CA 1 ATOM 5170 C C . ALA B 1 265 ? -12.601 68.013 -15.990 1.00 90.86 ? 263 ALA B C 1 ATOM 5171 O O . ALA B 1 265 ? -12.260 67.400 -14.968 1.00 89.02 ? 263 ALA B O 1 ATOM 5172 C CB . ALA B 1 265 ? -10.809 66.998 -17.424 1.00 91.04 ? 263 ALA B CB 1 ATOM 5173 N N . ARG B 1 266 ? -13.807 68.579 -16.149 1.00 86.66 ? 264 ARG B N 1 ATOM 5174 C CA . ARG B 1 266 ? -14.931 68.450 -15.221 1.00 85.99 ? 264 ARG B CA 1 ATOM 5175 C C . ARG B 1 266 ? -15.706 67.172 -15.581 1.00 87.63 ? 264 ARG B C 1 ATOM 5176 O O . ARG B 1 266 ? -16.092 66.419 -14.684 1.00 87.58 ? 264 ARG B O 1 ATOM 5177 C CB . ARG B 1 266 ? -15.853 69.680 -15.307 1.00 86.33 ? 264 ARG B CB 1 ATOM 5178 N N . VAL B 1 267 ? -15.882 66.917 -16.905 1.00 81.34 ? 265 VAL B N 1 ATOM 5179 C CA . VAL B 1 267 ? -16.575 65.757 -17.472 1.00 79.69 ? 265 VAL B CA 1 ATOM 5180 C C . VAL B 1 267 ? -15.755 64.475 -17.277 1.00 79.27 ? 265 VAL B C 1 ATOM 5181 O O . VAL B 1 267 ? -14.582 64.430 -17.646 1.00 78.84 ? 265 VAL B O 1 ATOM 5182 C CB . VAL B 1 267 ? -16.991 65.986 -18.963 1.00 83.93 ? 265 VAL B CB 1 ATOM 5183 C CG1 . VAL B 1 267 ? -17.715 64.774 -19.562 1.00 83.67 ? 265 VAL B CG1 1 ATOM 5184 C CG2 . VAL B 1 267 ? -17.830 67.253 -19.131 1.00 83.83 ? 265 VAL B CG2 1 ATOM 5185 N N . ALA B 1 268 ? -16.377 63.446 -16.687 1.00 73.39 ? 266 ALA B N 1 ATOM 5186 C CA . ALA B 1 268 ? -15.753 62.139 -16.477 1.00 72.29 ? 266 ALA B CA 1 ATOM 5187 C C . ALA B 1 268 ? -16.511 61.107 -17.315 1.00 73.14 ? 266 ALA B C 1 ATOM 5188 O O . ALA B 1 268 ? -17.745 61.085 -17.303 1.00 72.88 ? 266 ALA B O 1 ATOM 5189 C CB . ALA B 1 268 ? -15.771 61.758 -15.000 1.00 72.94 ? 266 ALA B CB 1 ATOM 5190 N N . VAL B 1 269 ? -15.776 60.292 -18.083 1.00 66.22 ? 267 VAL B N 1 ATOM 5191 C CA . VAL B 1 269 ? -16.379 59.278 -18.941 1.00 64.25 ? 267 VAL B CA 1 ATOM 5192 C C . VAL B 1 269 ? -16.108 57.884 -18.358 1.00 64.97 ? 267 VAL B C 1 ATOM 5193 O O . VAL B 1 269 ? -14.949 57.499 -18.220 1.00 64.34 ? 267 VAL B O 1 ATOM 5194 C CB . VAL B 1 269 ? -15.954 59.473 -20.422 1.00 67.69 ? 267 VAL B CB 1 ATOM 5195 C CG1 . VAL B 1 269 ? -16.418 58.315 -21.294 1.00 67.20 ? 267 VAL B CG1 1 ATOM 5196 C CG2 . VAL B 1 269 ? -16.496 60.798 -20.967 1.00 67.21 ? 267 VAL B CG2 1 ATOM 5197 N N . LEU B 1 270 ? -17.147 57.150 -18.007 1.00 60.69 ? 268 LEU B N 1 ATOM 5198 C CA . LEU B 1 270 ? -16.988 55.872 -17.335 1.00 60.64 ? 268 LEU B CA 1 ATOM 5199 C C . LEU B 1 270 ? -17.524 54.703 -18.128 1.00 63.63 ? 268 LEU B C 1 ATOM 5200 O O . LEU B 1 270 ? -18.590 54.789 -18.682 1.00 63.06 ? 268 LEU B O 1 ATOM 5201 C CB . LEU B 1 270 ? -17.721 55.897 -16.013 1.00 60.86 ? 268 LEU B CB 1 ATOM 5202 C CG . LEU B 1 270 ? -17.057 56.524 -14.811 1.00 65.09 ? 268 LEU B CG 1 ATOM 5203 C CD1 . LEU B 1 270 ? -16.362 57.804 -15.221 1.00 64.16 ? 268 LEU B CD1 1 ATOM 5204 C CD2 . LEU B 1 270 ? -18.117 56.781 -13.773 1.00 67.12 ? 268 LEU B CD2 1 ATOM 5205 N N . PHE B 1 271 ? -16.749 53.620 -18.157 1.00 59.14 ? 269 PHE B N 1 ATOM 5206 C CA . PHE B 1 271 ? -17.067 52.307 -18.734 1.00 57.14 ? 269 PHE B CA 1 ATOM 5207 C C . PHE B 1 271 ? -16.817 51.350 -17.585 1.00 60.76 ? 269 PHE B C 1 ATOM 5208 O O . PHE B 1 271 ? -15.796 50.665 -17.549 1.00 60.85 ? 269 PHE B O 1 ATOM 5209 C CB . PHE B 1 271 ? -16.174 51.984 -19.958 1.00 57.38 ? 269 PHE B CB 1 ATOM 5210 C CG . PHE B 1 271 ? -16.959 51.781 -21.230 1.00 57.06 ? 269 PHE B CG 1 ATOM 5211 C CD1 . PHE B 1 271 ? -17.574 50.562 -21.501 1.00 59.19 ? 269 PHE B CD1 1 ATOM 5212 C CD2 . PHE B 1 271 ? -17.141 52.827 -22.127 1.00 57.80 ? 269 PHE B CD2 1 ATOM 5213 C CE1 . PHE B 1 271 ? -18.349 50.388 -22.663 1.00 59.90 ? 269 PHE B CE1 1 ATOM 5214 C CE2 . PHE B 1 271 ? -17.899 52.645 -23.298 1.00 60.48 ? 269 PHE B CE2 1 ATOM 5215 C CZ . PHE B 1 271 ? -18.495 51.424 -23.559 1.00 58.30 ? 269 PHE B CZ 1 ATOM 5216 N N . THR B 1 272 ? -17.695 51.410 -16.575 1.00 57.50 ? 270 THR B N 1 ATOM 5217 C CA . THR B 1 272 ? -17.536 50.628 -15.352 1.00 57.66 ? 270 THR B CA 1 ATOM 5218 C C . THR B 1 272 ? -18.708 49.692 -15.028 1.00 62.43 ? 270 THR B C 1 ATOM 5219 O O . THR B 1 272 ? -19.833 49.837 -15.555 1.00 61.71 ? 270 THR B O 1 ATOM 5220 C CB . THR B 1 272 ? -17.215 51.543 -14.142 1.00 64.21 ? 270 THR B CB 1 ATOM 5221 O OG1 . THR B 1 272 ? -18.224 52.543 -14.005 1.00 59.70 ? 270 THR B OG1 1 ATOM 5222 C CG2 . THR B 1 272 ? -15.832 52.196 -14.240 1.00 65.02 ? 270 THR B CG2 1 ATOM 5223 N N . ARG B 1 273 ? -18.416 48.726 -14.120 1.00 58.16 ? 271 ARG B N 1 ATOM 5224 C CA . ARG B 1 273 ? -19.398 47.787 -13.591 1.00 57.38 ? 271 ARG B CA 1 ATOM 5225 C C . ARG B 1 273 ? -20.259 48.590 -12.613 1.00 60.60 ? 271 ARG B C 1 ATOM 5226 O O . ARG B 1 273 ? -19.883 49.706 -12.259 1.00 61.00 ? 271 ARG B O 1 ATOM 5227 C CB . ARG B 1 273 ? -18.716 46.569 -12.933 1.00 55.23 ? 271 ARG B CB 1 ATOM 5228 C CG . ARG B 1 273 ? -17.985 45.709 -13.948 1.00 60.10 ? 271 ARG B CG 1 ATOM 5229 C CD . ARG B 1 273 ? -17.704 44.296 -13.497 1.00 75.81 ? 271 ARG B CD 1 ATOM 5230 N NE . ARG B 1 273 ? -17.093 43.543 -14.596 1.00 91.17 ? 271 ARG B NE 1 ATOM 5231 C CZ . ARG B 1 273 ? -16.745 42.261 -14.547 1.00 108.50 ? 271 ARG B CZ 1 ATOM 5232 N NH1 . ARG B 1 273 ? -16.200 41.674 -15.608 1.00 87.60 ? 271 ARG B NH1 1 ATOM 5233 N NH2 . ARG B 1 273 ? -16.945 41.552 -13.441 1.00 100.09 ? 271 ARG B NH2 1 ATOM 5234 N N . SER B 1 274 ? -21.443 48.088 -12.258 1.00 56.35 ? 272 SER B N 1 ATOM 5235 C CA . SER B 1 274 ? -22.380 48.799 -11.381 1.00 54.94 ? 272 SER B CA 1 ATOM 5236 C C . SER B 1 274 ? -21.749 49.226 -10.070 1.00 58.79 ? 272 SER B C 1 ATOM 5237 O O . SER B 1 274 ? -21.713 50.422 -9.774 1.00 58.34 ? 272 SER B O 1 ATOM 5238 C CB . SER B 1 274 ? -23.621 47.953 -11.122 1.00 56.12 ? 272 SER B CB 1 ATOM 5239 O OG . SER B 1 274 ? -24.289 47.716 -12.343 1.00 60.45 ? 272 SER B OG 1 ATOM 5240 N N . GLU B 1 275 ? -21.205 48.252 -9.329 1.00 55.94 ? 273 GLU B N 1 ATOM 5241 C CA . GLU B 1 275 ? -20.554 48.416 -8.038 1.00 57.09 ? 273 GLU B CA 1 ATOM 5242 C C . GLU B 1 275 ? -19.275 49.251 -8.087 1.00 62.03 ? 273 GLU B C 1 ATOM 5243 O O . GLU B 1 275 ? -18.833 49.717 -7.043 1.00 63.03 ? 273 GLU B O 1 ATOM 5244 C CB . GLU B 1 275 ? -20.304 47.062 -7.356 1.00 59.03 ? 273 GLU B CB 1 ATOM 5245 C CG . GLU B 1 275 ? -19.871 45.925 -8.270 1.00 70.53 ? 273 GLU B CG 1 ATOM 5246 C CD . GLU B 1 275 ? -20.989 45.320 -9.100 1.00 85.43 ? 273 GLU B CD 1 ATOM 5247 O OE1 . GLU B 1 275 ? -20.975 45.545 -10.329 1.00 70.62 ? 273 GLU B OE1 1 ATOM 5248 O OE2 . GLU B 1 275 ? -21.914 44.700 -8.525 1.00 78.38 ? 273 GLU B OE2 1 ATOM 5249 N N . ASP B 1 276 ? -18.688 49.458 -9.267 1.00 58.05 ? 274 ASP B N 1 ATOM 5250 C CA . ASP B 1 276 ? -17.510 50.315 -9.379 1.00 58.09 ? 274 ASP B CA 1 ATOM 5251 C C . ASP B 1 276 ? -17.971 51.754 -9.536 1.00 62.68 ? 274 ASP B C 1 ATOM 5252 O O . ASP B 1 276 ? -17.429 52.653 -8.892 1.00 62.74 ? 274 ASP B O 1 ATOM 5253 C CB . ASP B 1 276 ? -16.607 49.880 -10.544 1.00 59.93 ? 274 ASP B CB 1 ATOM 5254 C CG . ASP B 1 276 ? -15.980 48.512 -10.339 1.00 72.66 ? 274 ASP B CG 1 ATOM 5255 O OD1 . ASP B 1 276 ? -15.839 48.086 -9.164 1.00 72.53 ? 274 ASP B OD1 1 ATOM 5256 O OD2 . ASP B 1 276 ? -15.648 47.854 -11.350 1.00 82.30 ? 274 ASP B OD2 1 ATOM 5257 N N . ALA B 1 277 ? -19.001 51.966 -10.365 1.00 59.58 ? 275 ALA B N 1 ATOM 5258 C CA . ALA B 1 277 ? -19.606 53.274 -10.583 1.00 59.93 ? 275 ALA B CA 1 ATOM 5259 C C . ALA B 1 277 ? -20.144 53.760 -9.238 1.00 63.97 ? 275 ALA B C 1 ATOM 5260 O O . ALA B 1 277 ? -19.857 54.893 -8.847 1.00 62.90 ? 275 ALA B O 1 ATOM 5261 C CB . ALA B 1 277 ? -20.734 53.168 -11.605 1.00 60.67 ? 275 ALA B CB 1 ATOM 5262 N N . ARG B 1 278 ? -20.838 52.848 -8.501 1.00 60.42 ? 276 ARG B N 1 ATOM 5263 C CA . ARG B 1 278 ? -21.408 53.057 -7.168 1.00 59.95 ? 276 ARG B CA 1 ATOM 5264 C C . ARG B 1 278 ? -20.366 53.611 -6.216 1.00 65.24 ? 276 ARG B C 1 ATOM 5265 O O . ARG B 1 278 ? -20.576 54.671 -5.635 1.00 63.72 ? 276 ARG B O 1 ATOM 5266 C CB . ARG B 1 278 ? -21.972 51.738 -6.606 1.00 56.50 ? 276 ARG B CB 1 ATOM 5267 C CG . ARG B 1 278 ? -22.756 51.916 -5.307 1.00 57.85 ? 276 ARG B CG 1 ATOM 5268 C CD . ARG B 1 278 ? -23.198 50.608 -4.712 1.00 58.16 ? 276 ARG B CD 1 ATOM 5269 N NE . ARG B 1 278 ? -22.072 49.846 -4.181 1.00 73.49 ? 276 ARG B NE 1 ATOM 5270 C CZ . ARG B 1 278 ? -22.004 48.518 -4.146 1.00 87.78 ? 276 ARG B CZ 1 ATOM 5271 N NH1 . ARG B 1 278 ? -23.006 47.781 -4.615 1.00 68.28 ? 276 ARG B NH1 1 ATOM 5272 N NH2 . ARG B 1 278 ? -20.929 47.915 -3.652 1.00 76.43 ? 276 ARG B NH2 1 ATOM 5273 N N . GLU B 1 279 ? -19.239 52.895 -6.089 1.00 65.00 ? 277 GLU B N 1 ATOM 5274 C CA . GLU B 1 279 ? -18.123 53.236 -5.222 1.00 66.14 ? 277 GLU B CA 1 ATOM 5275 C C . GLU B 1 279 ? -17.481 54.583 -5.549 1.00 73.02 ? 277 GLU B C 1 ATOM 5276 O O . GLU B 1 279 ? -17.393 55.433 -4.667 1.00 73.06 ? 277 GLU B O 1 ATOM 5277 C CB . GLU B 1 279 ? -17.094 52.106 -5.188 1.00 67.26 ? 277 GLU B CB 1 ATOM 5278 C CG . GLU B 1 279 ? -17.469 50.997 -4.217 1.00 78.15 ? 277 GLU B CG 1 ATOM 5279 C CD . GLU B 1 279 ? -18.100 51.477 -2.925 1.00 101.63 ? 277 GLU B CD 1 ATOM 5280 O OE1 . GLU B 1 279 ? -19.344 51.396 -2.813 1.00 96.65 ? 277 GLU B OE1 1 ATOM 5281 O OE2 . GLU B 1 279 ? -17.365 52.033 -2.076 1.00 98.34 ? 277 GLU B OE2 1 ATOM 5282 N N . LEU B 1 280 ? -17.103 54.799 -6.809 1.00 71.14 ? 278 LEU B N 1 ATOM 5283 C CA . LEU B 1 280 ? -16.499 56.037 -7.294 1.00 71.80 ? 278 LEU B CA 1 ATOM 5284 C C . LEU B 1 280 ? -17.429 57.236 -7.047 1.00 75.84 ? 278 LEU B C 1 ATOM 5285 O O . LEU B 1 280 ? -16.957 58.345 -6.803 1.00 75.12 ? 278 LEU B O 1 ATOM 5286 C CB . LEU B 1 280 ? -16.218 55.871 -8.792 1.00 72.41 ? 278 LEU B CB 1 ATOM 5287 C CG . LEU B 1 280 ? -15.395 56.942 -9.480 1.00 77.94 ? 278 LEU B CG 1 ATOM 5288 C CD1 . LEU B 1 280 ? -13.909 56.700 -9.280 1.00 78.50 ? 278 LEU B CD1 1 ATOM 5289 C CD2 . LEU B 1 280 ? -15.714 56.983 -10.950 1.00 80.54 ? 278 LEU B CD2 1 ATOM 5290 N N . LEU B 1 281 ? -18.744 56.999 -7.097 1.00 73.33 ? 279 LEU B N 1 ATOM 5291 C CA . LEU B 1 281 ? -19.781 58.006 -6.859 1.00 73.00 ? 279 LEU B CA 1 ATOM 5292 C C . LEU B 1 281 ? -19.884 58.283 -5.360 1.00 75.56 ? 279 LEU B C 1 ATOM 5293 O O . LEU B 1 281 ? -20.086 59.440 -4.968 1.00 74.34 ? 279 LEU B O 1 ATOM 5294 C CB . LEU B 1 281 ? -21.120 57.494 -7.414 1.00 73.14 ? 279 LEU B CB 1 ATOM 5295 C CG . LEU B 1 281 ? -22.198 58.495 -7.795 1.00 78.18 ? 279 LEU B CG 1 ATOM 5296 C CD1 . LEU B 1 281 ? -21.709 59.479 -8.829 1.00 78.09 ? 279 LEU B CD1 1 ATOM 5297 C CD2 . LEU B 1 281 ? -23.398 57.767 -8.355 1.00 82.15 ? 279 LEU B CD2 1 ATOM 5298 N N . ALA B 1 282 ? -19.714 57.226 -4.523 1.00 71.75 ? 280 ALA B N 1 ATOM 5299 C CA . ALA B 1 282 ? -19.748 57.343 -3.065 1.00 71.54 ? 280 ALA B CA 1 ATOM 5300 C C . ALA B 1 282 ? -18.513 58.120 -2.590 1.00 77.27 ? 280 ALA B C 1 ATOM 5301 O O . ALA B 1 282 ? -18.642 59.048 -1.779 1.00 77.88 ? 280 ALA B O 1 ATOM 5302 C CB . ALA B 1 282 ? -19.798 55.969 -2.421 1.00 71.92 ? 280 ALA B CB 1 ATOM 5303 N N . ALA B 1 283 ? -17.334 57.790 -3.164 1.00 73.33 ? 281 ALA B N 1 ATOM 5304 C CA . ALA B 1 283 ? -16.056 58.438 -2.891 1.00 73.26 ? 281 ALA B CA 1 ATOM 5305 C C . ALA B 1 283 ? -16.147 59.927 -3.201 1.00 78.29 ? 281 ALA B C 1 ATOM 5306 O O . ALA B 1 283 ? -15.597 60.733 -2.457 1.00 78.24 ? 281 ALA B O 1 ATOM 5307 C CB . ALA B 1 283 ? -14.957 57.794 -3.716 1.00 73.88 ? 281 ALA B CB 1 ATOM 5308 N N . SER B 1 284 ? -16.894 60.289 -4.259 1.00 75.48 ? 282 SER B N 1 ATOM 5309 C CA . SER B 1 284 ? -17.119 61.678 -4.666 1.00 75.57 ? 282 SER B CA 1 ATOM 5310 C C . SER B 1 284 ? -17.915 62.457 -3.598 1.00 81.01 ? 282 SER B C 1 ATOM 5311 O O . SER B 1 284 ? -17.459 63.524 -3.196 1.00 80.93 ? 282 SER B O 1 ATOM 5312 C CB . SER B 1 284 ? -17.798 61.748 -6.033 1.00 77.01 ? 282 SER B CB 1 ATOM 5313 O OG . SER B 1 284 ? -17.052 61.045 -7.011 1.00 79.10 ? 282 SER B OG 1 ATOM 5314 N N . GLN B 1 285 ? -19.063 61.908 -3.112 1.00 78.40 ? 283 GLN B N 1 ATOM 5315 C CA . GLN B 1 285 ? -19.885 62.527 -2.057 1.00 78.47 ? 283 GLN B CA 1 ATOM 5316 C C . GLN B 1 285 ? -19.076 62.634 -0.753 1.00 85.05 ? 283 GLN B C 1 ATOM 5317 O O . GLN B 1 285 ? -19.154 63.668 -0.091 1.00 85.25 ? 283 GLN B O 1 ATOM 5318 C CB . GLN B 1 285 ? -21.215 61.766 -1.838 1.00 79.19 ? 283 GLN B CB 1 ATOM 5319 C CG . GLN B 1 285 ? -22.256 62.546 -1.006 1.00 84.26 ? 283 GLN B CG 1 ATOM 5320 C CD . GLN B 1 285 ? -23.664 62.578 -1.597 1.00 95.35 ? 283 GLN B CD 1 ATOM 5321 O OE1 . GLN B 1 285 ? -23.868 62.815 -2.799 1.00 90.42 ? 283 GLN B OE1 1 ATOM 5322 N NE2 . GLN B 1 285 ? -24.681 62.429 -0.745 1.00 72.30 ? 283 GLN B NE2 1 ATOM 5323 N N . ARG B 1 286 ? -18.268 61.583 -0.429 1.00 82.50 ? 284 ARG B N 1 ATOM 5324 C CA . ARG B 1 286 ? -17.372 61.468 0.731 1.00 82.40 ? 284 ARG B CA 1 ATOM 5325 C C . ARG B 1 286 ? -16.449 62.690 0.869 1.00 87.59 ? 284 ARG B C 1 ATOM 5326 O O . ARG B 1 286 ? -16.443 63.342 1.914 1.00 87.54 ? 284 ARG B O 1 ATOM 5327 C CB . ARG B 1 286 ? -16.487 60.221 0.580 1.00 81.55 ? 284 ARG B CB 1 ATOM 5328 C CG . ARG B 1 286 ? -16.817 59.042 1.466 1.00 87.04 ? 284 ARG B CG 1 ATOM 5329 C CD . ARG B 1 286 ? -15.725 58.005 1.289 1.00 96.79 ? 284 ARG B CD 1 ATOM 5330 N NE . ARG B 1 286 ? -16.259 56.665 1.044 1.00 111.29 ? 284 ARG B NE 1 ATOM 5331 C CZ . ARG B 1 286 ? -15.799 55.824 0.122 1.00 128.61 ? 284 ARG B CZ 1 ATOM 5332 N NH1 . ARG B 1 286 ? -14.797 56.179 -0.672 1.00 113.53 ? 284 ARG B NH1 1 ATOM 5333 N NH2 . ARG B 1 286 ? -16.338 54.620 -0.014 1.00 121.10 ? 284 ARG B NH2 1 ATOM 5334 N N . LEU B 1 287 ? -15.664 62.985 -0.183 1.00 84.45 ? 285 LEU B N 1 ATOM 5335 C CA . LEU B 1 287 ? -14.724 64.108 -0.195 1.00 84.03 ? 285 LEU B CA 1 ATOM 5336 C C . LEU B 1 287 ? -15.242 65.306 -1.026 1.00 89.11 ? 285 LEU B C 1 ATOM 5337 O O . LEU B 1 287 ? -14.452 66.102 -1.534 1.00 88.68 ? 285 LEU B O 1 ATOM 5338 C CB . LEU B 1 287 ? -13.315 63.649 -0.623 1.00 83.53 ? 285 LEU B CB 1 ATOM 5339 C CG . LEU B 1 287 ? -13.184 62.940 -1.963 1.00 87.42 ? 285 LEU B CG 1 ATOM 5340 C CD1 . LEU B 1 287 ? -12.542 63.834 -2.988 1.00 87.86 ? 285 LEU B CD1 1 ATOM 5341 C CD2 . LEU B 1 287 ? -12.376 61.695 -1.824 1.00 88.70 ? 285 LEU B CD2 1 ATOM 5342 N N . ASN B 1 288 ? -16.583 65.444 -1.113 1.00 86.50 ? 286 ASN B N 1 ATOM 5343 C CA . ASN B 1 288 ? -17.309 66.507 -1.810 1.00 86.36 ? 286 ASN B CA 1 ATOM 5344 C C . ASN B 1 288 ? -16.638 66.930 -3.135 1.00 90.89 ? 286 ASN B C 1 ATOM 5345 O O . ASN B 1 288 ? -16.037 68.008 -3.216 1.00 91.65 ? 286 ASN B O 1 ATOM 5346 C CB . ASN B 1 288 ? -17.557 67.701 -0.871 1.00 87.59 ? 286 ASN B CB 1 ATOM 5347 C CG . ASN B 1 288 ? -18.589 68.693 -1.371 1.00 117.77 ? 286 ASN B CG 1 ATOM 5348 O OD1 . ASN B 1 288 ? -19.705 68.328 -1.778 1.00 114.09 ? 286 ASN B OD1 1 ATOM 5349 N ND2 . ASN B 1 288 ? -18.255 69.982 -1.312 1.00 108.46 ? 286 ASN B ND2 1 ATOM 5350 N N . ALA B 1 289 ? -16.713 66.053 -4.158 1.00 85.98 ? 287 ALA B N 1 ATOM 5351 C CA . ALA B 1 289 ? -16.166 66.303 -5.494 1.00 84.91 ? 287 ALA B CA 1 ATOM 5352 C C . ALA B 1 289 ? -17.299 66.437 -6.523 1.00 87.34 ? 287 ALA B C 1 ATOM 5353 O O . ALA B 1 289 ? -18.311 65.739 -6.412 1.00 87.18 ? 287 ALA B O 1 ATOM 5354 C CB . ALA B 1 289 ? -15.219 65.188 -5.887 1.00 85.47 ? 287 ALA B CB 1 ATOM 5355 N N . SER B 1 290 ? -17.131 67.336 -7.517 1.00 82.23 ? 288 SER B N 1 ATOM 5356 C CA . SER B 1 290 ? -18.141 67.599 -8.550 1.00 81.17 ? 288 SER B CA 1 ATOM 5357 C C . SER B 1 290 ? -17.665 67.293 -10.009 1.00 83.72 ? 288 SER B C 1 ATOM 5358 O O . SER B 1 290 ? -16.793 67.992 -10.554 1.00 83.07 ? 288 SER B O 1 ATOM 5359 C CB . SER B 1 290 ? -18.669 69.027 -8.420 1.00 83.88 ? 288 SER B CB 1 ATOM 5360 O OG . SER B 1 290 ? -19.664 69.330 -9.386 1.00 91.77 ? 288 SER B OG 1 ATOM 5361 N N . PHE B 1 291 ? -18.274 66.247 -10.633 1.00 77.65 ? 289 PHE B N 1 ATOM 5362 C CA . PHE B 1 291 ? -17.971 65.812 -12.000 1.00 75.04 ? 289 PHE B CA 1 ATOM 5363 C C . PHE B 1 291 ? -19.206 65.739 -12.891 1.00 77.21 ? 289 PHE B C 1 ATOM 5364 O O . PHE B 1 291 ? -20.327 65.572 -12.402 1.00 76.22 ? 289 PHE B O 1 ATOM 5365 C CB . PHE B 1 291 ? -17.296 64.443 -11.992 1.00 75.99 ? 289 PHE B CB 1 ATOM 5366 C CG . PHE B 1 291 ? -15.986 64.360 -11.251 1.00 76.84 ? 289 PHE B CG 1 ATOM 5367 C CD1 . PHE B 1 291 ? -14.791 64.711 -11.874 1.00 79.10 ? 289 PHE B CD1 1 ATOM 5368 C CD2 . PHE B 1 291 ? -15.935 63.870 -9.950 1.00 77.77 ? 289 PHE B CD2 1 ATOM 5369 C CE1 . PHE B 1 291 ? -13.571 64.596 -11.197 1.00 79.39 ? 289 PHE B CE1 1 ATOM 5370 C CE2 . PHE B 1 291 ? -14.711 63.744 -9.277 1.00 79.92 ? 289 PHE B CE2 1 ATOM 5371 C CZ . PHE B 1 291 ? -13.539 64.114 -9.902 1.00 77.80 ? 289 PHE B CZ 1 ATOM 5372 N N . THR B 1 292 ? -18.993 65.864 -14.211 1.00 73.25 ? 290 THR B N 1 ATOM 5373 C CA . THR B 1 292 ? -20.052 65.725 -15.211 1.00 72.43 ? 290 THR B CA 1 ATOM 5374 C C . THR B 1 292 ? -19.881 64.304 -15.786 1.00 74.07 ? 290 THR B C 1 ATOM 5375 O O . THR B 1 292 ? -19.166 64.101 -16.773 1.00 73.84 ? 290 THR B O 1 ATOM 5376 C CB . THR B 1 292 ? -20.038 66.888 -16.238 1.00 79.67 ? 290 THR B CB 1 ATOM 5377 O OG1 . THR B 1 292 ? -20.041 68.138 -15.543 1.00 83.14 ? 290 THR B OG1 1 ATOM 5378 C CG2 . THR B 1 292 ? -21.216 66.829 -17.240 1.00 74.63 ? 290 THR B CG2 1 ATOM 5379 N N . TRP B 1 293 ? -20.491 63.311 -15.112 1.00 67.53 ? 291 TRP B N 1 ATOM 5380 C CA . TRP B 1 293 ? -20.396 61.917 -15.528 1.00 65.01 ? 291 TRP B CA 1 ATOM 5381 C C . TRP B 1 293 ? -21.143 61.638 -16.839 1.00 66.00 ? 291 TRP B C 1 ATOM 5382 O O . TRP B 1 293 ? -22.273 62.089 -17.045 1.00 64.80 ? 291 TRP B O 1 ATOM 5383 C CB . TRP B 1 293 ? -20.912 60.965 -14.451 1.00 62.96 ? 291 TRP B CB 1 ATOM 5384 C CG . TRP B 1 293 ? -20.632 61.346 -13.031 1.00 63.91 ? 291 TRP B CG 1 ATOM 5385 C CD1 . TRP B 1 293 ? -21.492 61.957 -12.166 1.00 66.95 ? 291 TRP B CD1 1 ATOM 5386 C CD2 . TRP B 1 293 ? -19.456 61.031 -12.271 1.00 63.60 ? 291 TRP B CD2 1 ATOM 5387 N NE1 . TRP B 1 293 ? -20.911 62.077 -10.926 1.00 66.52 ? 291 TRP B NE1 1 ATOM 5388 C CE2 . TRP B 1 293 ? -19.668 61.495 -10.956 1.00 67.89 ? 291 TRP B CE2 1 ATOM 5389 C CE3 . TRP B 1 293 ? -18.229 60.425 -12.580 1.00 64.76 ? 291 TRP B CE3 1 ATOM 5390 C CZ2 . TRP B 1 293 ? -18.708 61.348 -9.944 1.00 67.27 ? 291 TRP B CZ2 1 ATOM 5391 C CZ3 . TRP B 1 293 ? -17.275 60.288 -11.583 1.00 66.17 ? 291 TRP B CZ3 1 ATOM 5392 C CH2 . TRP B 1 293 ? -17.517 60.743 -10.283 1.00 66.82 ? 291 TRP B CH2 1 ATOM 5393 N N . VAL B 1 294 ? -20.477 60.901 -17.720 1.00 60.53 ? 292 VAL B N 1 ATOM 5394 C CA . VAL B 1 294 ? -21.009 60.364 -18.959 1.00 59.91 ? 292 VAL B CA 1 ATOM 5395 C C . VAL B 1 294 ? -20.688 58.872 -18.781 1.00 63.05 ? 292 VAL B C 1 ATOM 5396 O O . VAL B 1 294 ? -19.511 58.508 -18.784 1.00 64.29 ? 292 VAL B O 1 ATOM 5397 C CB . VAL B 1 294 ? -20.396 61.029 -20.212 1.00 64.14 ? 292 VAL B CB 1 ATOM 5398 C CG1 . VAL B 1 294 ? -20.638 60.187 -21.465 1.00 64.43 ? 292 VAL B CG1 1 ATOM 5399 C CG2 . VAL B 1 294 ? -20.964 62.431 -20.401 1.00 63.80 ? 292 VAL B CG2 1 ATOM 5400 N N . ALA B 1 295 ? -21.700 58.034 -18.458 1.00 56.85 ? 293 ALA B N 1 ATOM 5401 C CA . ALA B 1 295 ? -21.402 56.634 -18.125 1.00 55.27 ? 293 ALA B CA 1 ATOM 5402 C C . ALA B 1 295 ? -22.136 55.601 -18.947 1.00 56.01 ? 293 ALA B C 1 ATOM 5403 O O . ALA B 1 295 ? -23.264 55.833 -19.377 1.00 54.14 ? 293 ALA B O 1 ATOM 5404 C CB . ALA B 1 295 ? -21.632 56.385 -16.641 1.00 56.01 ? 293 ALA B CB 1 ATOM 5405 N N . SER B 1 296 ? -21.482 54.430 -19.127 1.00 52.08 ? 294 SER B N 1 ATOM 5406 C CA . SER B 1 296 ? -21.962 53.270 -19.898 1.00 50.44 ? 294 SER B CA 1 ATOM 5407 C C . SER B 1 296 ? -23.061 52.452 -19.207 1.00 53.02 ? 294 SER B C 1 ATOM 5408 O O . SER B 1 296 ? -23.364 52.689 -18.036 1.00 52.84 ? 294 SER B O 1 ATOM 5409 C CB . SER B 1 296 ? -20.795 52.371 -20.289 1.00 50.57 ? 294 SER B CB 1 ATOM 5410 O OG . SER B 1 296 ? -20.287 51.734 -19.133 1.00 52.08 ? 294 SER B OG 1 ATOM 5411 N N . ASP B 1 297 ? -23.627 51.462 -19.944 1.00 48.30 ? 295 ASP B N 1 ATOM 5412 C CA . ASP B 1 297 ? -24.721 50.562 -19.565 1.00 46.87 ? 295 ASP B CA 1 ATOM 5413 C C . ASP B 1 297 ? -24.578 49.909 -18.176 1.00 50.20 ? 295 ASP B C 1 ATOM 5414 O O . ASP B 1 297 ? -25.599 49.648 -17.537 1.00 50.63 ? 295 ASP B O 1 ATOM 5415 C CB . ASP B 1 297 ? -24.971 49.501 -20.653 1.00 48.38 ? 295 ASP B CB 1 ATOM 5416 C CG . ASP B 1 297 ? -23.982 48.347 -20.683 1.00 59.81 ? 295 ASP B CG 1 ATOM 5417 O OD1 . ASP B 1 297 ? -22.814 48.566 -21.096 1.00 58.80 ? 295 ASP B OD1 1 ATOM 5418 O OD2 . ASP B 1 297 ? -24.379 47.222 -20.324 1.00 67.12 ? 295 ASP B OD2 1 ATOM 5419 N N . GLY B 1 298 ? -23.348 49.659 -17.734 1.00 46.93 ? 296 GLY B N 1 ATOM 5420 C CA . GLY B 1 298 ? -23.041 49.120 -16.407 1.00 47.63 ? 296 GLY B CA 1 ATOM 5421 C C . GLY B 1 298 ? -23.737 49.889 -15.304 1.00 54.93 ? 296 GLY B C 1 ATOM 5422 O O . GLY B 1 298 ? -24.454 49.294 -14.501 1.00 56.10 ? 296 GLY B O 1 ATOM 5423 N N . TRP B 1 299 ? -23.623 51.226 -15.329 1.00 53.04 ? 297 TRP B N 1 ATOM 5424 C CA . TRP B 1 299 ? -24.319 52.126 -14.419 1.00 54.19 ? 297 TRP B CA 1 ATOM 5425 C C . TRP B 1 299 ? -25.768 52.257 -14.951 1.00 55.28 ? 297 TRP B C 1 ATOM 5426 O O . TRP B 1 299 ? -26.701 52.138 -14.161 1.00 54.10 ? 297 TRP B O 1 ATOM 5427 C CB . TRP B 1 299 ? -23.577 53.495 -14.364 1.00 54.86 ? 297 TRP B CB 1 ATOM 5428 C CG . TRP B 1 299 ? -24.294 54.703 -13.783 1.00 57.54 ? 297 TRP B CG 1 ATOM 5429 C CD1 . TRP B 1 299 ? -25.642 54.925 -13.719 1.00 60.65 ? 297 TRP B CD1 1 ATOM 5430 C CD2 . TRP B 1 299 ? -23.672 55.891 -13.265 1.00 58.17 ? 297 TRP B CD2 1 ATOM 5431 N NE1 . TRP B 1 299 ? -25.897 56.169 -13.197 1.00 60.49 ? 297 TRP B NE1 1 ATOM 5432 C CE2 . TRP B 1 299 ? -24.707 56.777 -12.889 1.00 62.04 ? 297 TRP B CE2 1 ATOM 5433 C CE3 . TRP B 1 299 ? -22.332 56.284 -13.057 1.00 59.88 ? 297 TRP B CE3 1 ATOM 5434 C CZ2 . TRP B 1 299 ? -24.450 58.051 -12.370 1.00 61.53 ? 297 TRP B CZ2 1 ATOM 5435 C CZ3 . TRP B 1 299 ? -22.077 57.542 -12.527 1.00 61.19 ? 297 TRP B CZ3 1 ATOM 5436 C CH2 . TRP B 1 299 ? -23.127 58.406 -12.179 1.00 61.82 ? 297 TRP B CH2 1 ATOM 5437 N N . GLY B 1 300 ? -25.924 52.512 -16.260 1.00 50.11 ? 298 GLY B N 1 ATOM 5438 C CA . GLY B 1 300 ? -27.214 52.702 -16.922 1.00 50.20 ? 298 GLY B CA 1 ATOM 5439 C C . GLY B 1 300 ? -28.169 53.580 -16.141 1.00 56.70 ? 298 GLY B C 1 ATOM 5440 O O . GLY B 1 300 ? -27.785 54.665 -15.717 1.00 57.54 ? 298 GLY B O 1 ATOM 5441 N N . ALA B 1 301 ? -29.412 53.118 -15.910 1.00 54.35 ? 299 ALA B N 1 ATOM 5442 C CA . ALA B 1 301 ? -30.385 53.856 -15.075 1.00 53.39 ? 299 ALA B CA 1 ATOM 5443 C C . ALA B 1 301 ? -30.713 53.043 -13.785 1.00 56.23 ? 299 ALA B C 1 ATOM 5444 O O . ALA B 1 301 ? -31.870 52.924 -13.369 1.00 55.27 ? 299 ALA B O 1 ATOM 5445 C CB . ALA B 1 301 ? -31.637 54.210 -15.862 1.00 53.66 ? 299 ALA B CB 1 ATOM 5446 N N . LEU B 1 302 ? -29.656 52.496 -13.163 1.00 52.60 ? 300 LEU B N 1 ATOM 5447 C CA . LEU B 1 302 ? -29.740 51.740 -11.925 1.00 53.63 ? 300 LEU B CA 1 ATOM 5448 C C . LEU B 1 302 ? -29.797 52.674 -10.724 1.00 59.31 ? 300 LEU B C 1 ATOM 5449 O O . LEU B 1 302 ? -28.890 53.491 -10.528 1.00 58.62 ? 300 LEU B O 1 ATOM 5450 C CB . LEU B 1 302 ? -28.582 50.729 -11.774 1.00 53.70 ? 300 LEU B CB 1 ATOM 5451 C CG . LEU B 1 302 ? -28.535 49.579 -12.797 1.00 58.42 ? 300 LEU B CG 1 ATOM 5452 C CD1 . LEU B 1 302 ? -27.299 48.766 -12.616 1.00 58.61 ? 300 LEU B CD1 1 ATOM 5453 C CD2 . LEU B 1 302 ? -29.735 48.665 -12.688 1.00 60.41 ? 300 LEU B CD2 1 ATOM 5454 N N . GLU B 1 303 ? -30.891 52.559 -9.931 1.00 56.64 ? 301 GLU B N 1 ATOM 5455 C CA . GLU B 1 303 ? -31.122 53.353 -8.729 1.00 55.97 ? 301 GLU B CA 1 ATOM 5456 C C . GLU B 1 303 ? -30.091 52.941 -7.667 1.00 60.59 ? 301 GLU B C 1 ATOM 5457 O O . GLU B 1 303 ? -29.616 53.812 -6.956 1.00 61.44 ? 301 GLU B O 1 ATOM 5458 C CB . GLU B 1 303 ? -32.571 53.213 -8.219 1.00 56.95 ? 301 GLU B CB 1 ATOM 5459 C CG . GLU B 1 303 ? -33.664 53.632 -9.199 1.00 64.86 ? 301 GLU B CG 1 ATOM 5460 C CD . GLU B 1 303 ? -34.075 55.097 -9.266 1.00 98.01 ? 301 GLU B CD 1 ATOM 5461 O OE1 . GLU B 1 303 ? -33.492 55.934 -8.538 1.00 101.92 ? 301 GLU B OE1 1 ATOM 5462 O OE2 . GLU B 1 303 ? -34.985 55.411 -10.069 1.00 94.25 ? 301 GLU B OE2 1 ATOM 5463 N N . SER B 1 304 ? -29.692 51.644 -7.629 1.00 56.26 ? 302 SER B N 1 ATOM 5464 C CA . SER B 1 304 ? -28.693 51.040 -6.720 1.00 55.74 ? 302 SER B CA 1 ATOM 5465 C C . SER B 1 304 ? -27.295 51.655 -6.798 1.00 60.70 ? 302 SER B C 1 ATOM 5466 O O . SER B 1 304 ? -26.583 51.697 -5.797 1.00 61.36 ? 302 SER B O 1 ATOM 5467 C CB . SER B 1 304 ? -28.592 49.538 -6.995 1.00 20.00 ? 302 SER B CB 1 ATOM 5468 O OG . SER B 1 304 ? -28.072 49.291 -8.290 1.00 20.00 ? 302 SER B OG 1 ATOM 5469 N N . VAL B 1 305 ? -26.890 52.075 -7.988 1.00 58.16 ? 303 VAL B N 1 ATOM 5470 C CA . VAL B 1 305 ? -25.590 52.685 -8.281 1.00 59.04 ? 303 VAL B CA 1 ATOM 5471 C C . VAL B 1 305 ? -25.505 54.057 -7.564 1.00 67.33 ? 303 VAL B C 1 ATOM 5472 O O . VAL B 1 305 ? -24.485 54.374 -6.945 1.00 66.82 ? 303 VAL B O 1 ATOM 5473 C CB . VAL B 1 305 ? -25.410 52.773 -9.844 1.00 61.83 ? 303 VAL B CB 1 ATOM 5474 C CG1 . VAL B 1 305 ? -24.522 53.929 -10.291 1.00 61.39 ? 303 VAL B CG1 1 ATOM 5475 C CG2 . VAL B 1 305 ? -24.910 51.456 -10.423 1.00 61.37 ? 303 VAL B CG2 1 ATOM 5476 N N . VAL B 1 306 ? -26.606 54.826 -7.614 1.00 66.96 ? 304 VAL B N 1 ATOM 5477 C CA . VAL B 1 306 ? -26.691 56.173 -7.078 1.00 68.97 ? 304 VAL B CA 1 ATOM 5478 C C . VAL B 1 306 ? -27.179 56.244 -5.629 1.00 76.75 ? 304 VAL B C 1 ATOM 5479 O O . VAL B 1 306 ? -26.661 57.069 -4.869 1.00 77.61 ? 304 VAL B O 1 ATOM 5480 C CB . VAL B 1 306 ? -27.528 57.083 -7.994 1.00 73.84 ? 304 VAL B CB 1 ATOM 5481 C CG1 . VAL B 1 306 ? -27.534 58.504 -7.460 1.00 74.27 ? 304 VAL B CG1 1 ATOM 5482 C CG2 . VAL B 1 306 ? -26.985 57.066 -9.418 1.00 73.51 ? 304 VAL B CG2 1 ATOM 5483 N N . ALA B 1 307 ? -28.184 55.424 -5.257 1.00 73.67 ? 305 ALA B N 1 ATOM 5484 C CA . ALA B 1 307 ? -28.771 55.361 -3.917 1.00 72.93 ? 305 ALA B CA 1 ATOM 5485 C C . ALA B 1 307 ? -27.737 55.606 -2.822 1.00 75.65 ? 305 ALA B C 1 ATOM 5486 O O . ALA B 1 307 ? -26.815 54.800 -2.655 1.00 74.49 ? 305 ALA B O 1 ATOM 5487 C CB . ALA B 1 307 ? -29.436 54.013 -3.706 1.00 73.69 ? 305 ALA B CB 1 ATOM 5488 N N . GLY B 1 308 ? -27.871 56.754 -2.151 1.00 72.41 ? 306 GLY B N 1 ATOM 5489 C CA . GLY B 1 308 ? -27.005 57.181 -1.055 1.00 72.38 ? 306 GLY B CA 1 ATOM 5490 C C . GLY B 1 308 ? -26.025 58.291 -1.387 1.00 76.58 ? 306 GLY B C 1 ATOM 5491 O O . GLY B 1 308 ? -25.652 59.065 -0.502 1.00 76.49 ? 306 GLY B O 1 ATOM 5492 N N . SER B 1 309 ? -25.583 58.366 -2.653 1.00 72.76 ? 307 SER B N 1 ATOM 5493 C CA . SER B 1 309 ? -24.622 59.368 -3.147 1.00 72.59 ? 307 SER B CA 1 ATOM 5494 C C . SER B 1 309 ? -25.279 60.247 -4.232 1.00 75.92 ? 307 SER B C 1 ATOM 5495 O O . SER B 1 309 ? -24.618 60.638 -5.206 1.00 76.46 ? 307 SER B O 1 ATOM 5496 C CB . SER B 1 309 ? -23.387 58.672 -3.720 1.00 77.24 ? 307 SER B CB 1 ATOM 5497 O OG . SER B 1 309 ? -23.680 57.878 -4.859 1.00 89.64 ? 307 SER B OG 1 ATOM 5498 N N . GLU B 1 310 ? -26.585 60.543 -4.060 1.00 70.29 ? 308 GLU B N 1 ATOM 5499 C CA . GLU B 1 310 ? -27.394 61.307 -5.003 1.00 69.70 ? 308 GLU B CA 1 ATOM 5500 C C . GLU B 1 310 ? -26.833 62.656 -5.400 1.00 74.21 ? 308 GLU B C 1 ATOM 5501 O O . GLU B 1 310 ? -26.818 62.972 -6.593 1.00 73.23 ? 308 GLU B O 1 ATOM 5502 C CB . GLU B 1 310 ? -28.815 61.473 -4.484 1.00 70.80 ? 308 GLU B CB 1 ATOM 5503 C CG . GLU B 1 310 ? -29.715 60.329 -4.891 1.00 75.70 ? 308 GLU B CG 1 ATOM 5504 C CD . GLU B 1 310 ? -30.171 59.401 -3.785 1.00 82.49 ? 308 GLU B CD 1 ATOM 5505 O OE1 . GLU B 1 310 ? -29.569 59.413 -2.685 1.00 51.91 ? 308 GLU B OE1 1 ATOM 5506 O OE2 . GLU B 1 310 ? -31.144 58.652 -4.032 1.00 78.55 ? 308 GLU B OE2 1 ATOM 5507 N N . GLY B 1 311 ? -26.400 63.433 -4.407 1.00 72.58 ? 309 GLY B N 1 ATOM 5508 C CA . GLY B 1 311 ? -25.843 64.769 -4.599 1.00 73.43 ? 309 GLY B CA 1 ATOM 5509 C C . GLY B 1 311 ? -24.741 64.835 -5.640 1.00 78.63 ? 309 GLY B C 1 ATOM 5510 O O . GLY B 1 311 ? -24.834 65.627 -6.585 1.00 78.26 ? 309 GLY B O 1 ATOM 5511 N N . ALA B 1 312 ? -23.715 63.958 -5.482 1.00 75.90 ? 310 ALA B N 1 ATOM 5512 C CA . ALA B 1 312 ? -22.554 63.791 -6.371 1.00 76.08 ? 310 ALA B CA 1 ATOM 5513 C C . ALA B 1 312 ? -22.993 63.422 -7.798 1.00 80.89 ? 310 ALA B C 1 ATOM 5514 O O . ALA B 1 312 ? -22.473 63.979 -8.774 1.00 81.15 ? 310 ALA B O 1 ATOM 5515 C CB . ALA B 1 312 ? -21.630 62.708 -5.818 1.00 76.69 ? 310 ALA B CB 1 ATOM 5516 N N . ALA B 1 313 ? -23.975 62.501 -7.901 1.00 76.17 ? 311 ALA B N 1 ATOM 5517 C CA . ALA B 1 313 ? -24.525 62.008 -9.157 1.00 74.85 ? 311 ALA B CA 1 ATOM 5518 C C . ALA B 1 313 ? -25.359 63.018 -9.911 1.00 75.55 ? 311 ALA B C 1 ATOM 5519 O O . ALA B 1 313 ? -25.424 62.924 -11.139 1.00 75.05 ? 311 ALA B O 1 ATOM 5520 C CB . ALA B 1 313 ? -25.344 60.762 -8.910 1.00 75.60 ? 311 ALA B CB 1 ATOM 5521 N N . GLU B 1 314 ? -26.018 63.959 -9.203 1.00 70.17 ? 312 GLU B N 1 ATOM 5522 C CA . GLU B 1 314 ? -26.885 64.957 -9.843 1.00 69.52 ? 312 GLU B CA 1 ATOM 5523 C C . GLU B 1 314 ? -26.237 65.567 -11.100 1.00 72.98 ? 312 GLU B C 1 ATOM 5524 O O . GLU B 1 314 ? -25.099 66.046 -11.037 1.00 73.80 ? 312 GLU B O 1 ATOM 5525 C CB . GLU B 1 314 ? -27.331 66.042 -8.842 1.00 70.61 ? 312 GLU B CB 1 ATOM 5526 C CG . GLU B 1 314 ? -28.467 66.920 -9.356 1.00 77.72 ? 312 GLU B CG 1 ATOM 5527 C CD . GLU B 1 314 ? -29.017 67.986 -8.421 1.00 89.17 ? 312 GLU B CD 1 ATOM 5528 O OE1 . GLU B 1 314 ? -28.735 67.939 -7.199 1.00 78.17 ? 312 GLU B OE1 1 ATOM 5529 O OE2 . GLU B 1 314 ? -29.782 68.845 -8.913 1.00 72.87 ? 312 GLU B OE2 1 ATOM 5530 N N . GLY B 1 315 ? -26.932 65.455 -12.228 1.00 67.35 ? 313 GLY B N 1 ATOM 5531 C CA . GLY B 1 315 ? -26.463 65.981 -13.505 1.00 66.41 ? 313 GLY B CA 1 ATOM 5532 C C . GLY B 1 315 ? -25.837 65.005 -14.489 1.00 68.31 ? 313 GLY B C 1 ATOM 5533 O O . GLY B 1 315 ? -25.650 65.370 -15.652 1.00 68.35 ? 313 GLY B O 1 ATOM 5534 N N . ALA B 1 316 ? -25.505 63.761 -14.047 1.00 62.06 ? 314 ALA B N 1 ATOM 5535 C CA . ALA B 1 316 ? -24.894 62.712 -14.882 1.00 59.70 ? 314 ALA B CA 1 ATOM 5536 C C . ALA B 1 316 ? -25.733 62.355 -16.092 1.00 61.96 ? 314 ALA B C 1 ATOM 5537 O O . ALA B 1 316 ? -26.952 62.407 -16.025 1.00 60.12 ? 314 ALA B O 1 ATOM 5538 C CB . ALA B 1 316 ? -24.638 61.465 -14.057 1.00 59.89 ? 314 ALA B CB 1 ATOM 5539 N N . ILE B 1 317 ? -25.064 62.039 -17.210 1.00 60.14 ? 315 ILE B N 1 ATOM 5540 C CA . ILE B 1 317 ? -25.651 61.559 -18.464 1.00 60.07 ? 315 ILE B CA 1 ATOM 5541 C C . ILE B 1 317 ? -25.224 60.090 -18.622 1.00 65.91 ? 315 ILE B C 1 ATOM 5542 O O . ILE B 1 317 ? -24.022 59.798 -18.626 1.00 66.55 ? 315 ILE B O 1 ATOM 5543 C CB . ILE B 1 317 ? -25.270 62.418 -19.681 1.00 62.79 ? 315 ILE B CB 1 ATOM 5544 C CG1 . ILE B 1 317 ? -25.960 63.796 -19.583 1.00 62.73 ? 315 ILE B CG1 1 ATOM 5545 C CG2 . ILE B 1 317 ? -25.635 61.674 -20.986 1.00 63.32 ? 315 ILE B CG2 1 ATOM 5546 C CD1 . ILE B 1 317 ? -25.974 64.590 -20.822 1.00 67.25 ? 315 ILE B CD1 1 ATOM 5547 N N . THR B 1 318 ? -26.198 59.155 -18.667 1.00 61.68 ? 316 THR B N 1 ATOM 5548 C CA . THR B 1 318 ? -25.852 57.732 -18.739 1.00 60.14 ? 316 THR B CA 1 ATOM 5549 C C . THR B 1 318 ? -26.514 57.013 -19.903 1.00 62.76 ? 316 THR B C 1 ATOM 5550 O O . THR B 1 318 ? -27.575 57.404 -20.385 1.00 62.10 ? 316 THR B O 1 ATOM 5551 C CB . THR B 1 318 ? -26.089 57.009 -17.399 1.00 56.66 ? 316 THR B CB 1 ATOM 5552 O OG1 . THR B 1 318 ? -27.478 56.879 -17.154 1.00 42.93 ? 316 THR B OG1 1 ATOM 5553 C CG2 . THR B 1 318 ? -25.435 57.713 -16.228 1.00 56.91 ? 316 THR B CG2 1 ATOM 5554 N N . ILE B 1 319 ? -25.859 55.947 -20.345 1.00 59.77 ? 317 ILE B N 1 ATOM 5555 C CA . ILE B 1 319 ? -26.284 55.104 -21.460 1.00 58.95 ? 317 ILE B CA 1 ATOM 5556 C C . ILE B 1 319 ? -26.834 53.769 -20.961 1.00 60.44 ? 317 ILE B C 1 ATOM 5557 O O . ILE B 1 319 ? -26.261 53.128 -20.077 1.00 59.39 ? 317 ILE B O 1 ATOM 5558 C CB . ILE B 1 319 ? -25.139 54.937 -22.519 1.00 62.07 ? 317 ILE B CB 1 ATOM 5559 C CG1 . ILE B 1 319 ? -24.502 56.308 -22.930 1.00 62.44 ? 317 ILE B CG1 1 ATOM 5560 C CG2 . ILE B 1 319 ? -25.578 54.121 -23.757 1.00 62.73 ? 317 ILE B CG2 1 ATOM 5561 C CD1 . ILE B 1 319 ? -25.494 57.419 -23.402 1.00 67.49 ? 317 ILE B CD1 1 ATOM 5562 N N . GLU B 1 320 ? -27.991 53.407 -21.501 1.00 55.81 ? 318 GLU B N 1 ATOM 5563 C CA . GLU B 1 320 ? -28.680 52.147 -21.284 1.00 54.60 ? 318 GLU B CA 1 ATOM 5564 C C . GLU B 1 320 ? -29.016 51.674 -22.677 1.00 58.54 ? 318 GLU B C 1 ATOM 5565 O O . GLU B 1 320 ? -29.522 52.461 -23.482 1.00 57.92 ? 318 GLU B O 1 ATOM 5566 C CB . GLU B 1 320 ? -29.965 52.330 -20.474 1.00 55.09 ? 318 GLU B CB 1 ATOM 5567 C CG . GLU B 1 320 ? -30.144 51.274 -19.405 1.00 60.55 ? 318 GLU B CG 1 ATOM 5568 C CD . GLU B 1 320 ? -31.363 51.389 -18.503 1.00 78.68 ? 318 GLU B CD 1 ATOM 5569 O OE1 . GLU B 1 320 ? -32.506 51.270 -19.012 1.00 81.14 ? 318 GLU B OE1 1 ATOM 5570 O OE2 . GLU B 1 320 ? -31.165 51.479 -17.268 1.00 48.64 ? 318 GLU B OE2 1 ATOM 5571 N N . LEU B 1 321 ? -28.675 50.416 -22.985 1.00 54.55 ? 319 LEU B N 1 ATOM 5572 C CA . LEU B 1 321 ? -28.990 49.793 -24.265 1.00 54.32 ? 319 LEU B CA 1 ATOM 5573 C C . LEU B 1 321 ? -30.503 49.897 -24.398 1.00 58.98 ? 319 LEU B C 1 ATOM 5574 O O . LEU B 1 321 ? -31.226 49.613 -23.431 1.00 59.73 ? 319 LEU B O 1 ATOM 5575 C CB . LEU B 1 321 ? -28.566 48.310 -24.253 1.00 53.92 ? 319 LEU B CB 1 ATOM 5576 C CG . LEU B 1 321 ? -27.176 47.972 -24.777 1.00 57.43 ? 319 LEU B CG 1 ATOM 5577 C CD1 . LEU B 1 321 ? -26.078 48.513 -23.890 1.00 56.85 ? 319 LEU B CD1 1 ATOM 5578 C CD2 . LEU B 1 321 ? -27.003 46.512 -24.849 1.00 59.26 ? 319 LEU B CD2 1 ATOM 5579 N N . ALA B 1 322 ? -30.961 50.414 -25.536 1.00 54.36 ? 320 ALA B N 1 ATOM 5580 C CA . ALA B 1 322 ? -32.373 50.635 -25.816 1.00 53.85 ? 320 ALA B CA 1 ATOM 5581 C C . ALA B 1 322 ? -33.202 49.347 -25.758 1.00 55.17 ? 320 ALA B C 1 ATOM 5582 O O . ALA B 1 322 ? -32.952 48.395 -26.521 1.00 54.52 ? 320 ALA B O 1 ATOM 5583 C CB . ALA B 1 322 ? -32.548 51.333 -27.162 1.00 54.55 ? 320 ALA B CB 1 ATOM 5584 N N . SER B 1 323 ? -34.168 49.328 -24.818 1.00 48.70 ? 321 SER B N 1 ATOM 5585 C CA . SER B 1 323 ? -35.079 48.210 -24.604 1.00 47.95 ? 321 SER B CA 1 ATOM 5586 C C . SER B 1 323 ? -36.443 48.722 -24.157 1.00 49.80 ? 321 SER B C 1 ATOM 5587 O O . SER B 1 323 ? -36.605 49.911 -23.914 1.00 49.89 ? 321 SER B O 1 ATOM 5588 C CB . SER B 1 323 ? -34.518 47.256 -23.548 1.00 51.42 ? 321 SER B CB 1 ATOM 5589 O OG . SER B 1 323 ? -34.533 47.853 -22.260 1.00 57.60 ? 321 SER B OG 1 ATOM 5590 N N . TYR B 1 324 ? -37.408 47.831 -24.009 1.00 44.61 ? 322 TYR B N 1 ATOM 5591 C CA . TYR B 1 324 ? -38.730 48.222 -23.534 1.00 44.42 ? 322 TYR B CA 1 ATOM 5592 C C . TYR B 1 324 ? -39.171 47.237 -22.457 1.00 50.19 ? 322 TYR B C 1 ATOM 5593 O O . TYR B 1 324 ? -38.742 46.075 -22.507 1.00 50.48 ? 322 TYR B O 1 ATOM 5594 C CB . TYR B 1 324 ? -39.747 48.250 -24.702 1.00 44.22 ? 322 TYR B CB 1 ATOM 5595 C CG . TYR B 1 324 ? -39.637 47.065 -25.637 1.00 44.52 ? 322 TYR B CG 1 ATOM 5596 C CD1 . TYR B 1 324 ? -40.109 45.805 -25.262 1.00 45.67 ? 322 TYR B CD1 1 ATOM 5597 C CD2 . TYR B 1 324 ? -39.050 47.196 -26.896 1.00 43.96 ? 322 TYR B CD2 1 ATOM 5598 C CE1 . TYR B 1 324 ? -40.002 44.712 -26.117 1.00 46.14 ? 322 TYR B CE1 1 ATOM 5599 C CE2 . TYR B 1 324 ? -38.952 46.111 -27.763 1.00 43.97 ? 322 TYR B CE2 1 ATOM 5600 C CZ . TYR B 1 324 ? -39.430 44.873 -27.369 1.00 54.74 ? 322 TYR B CZ 1 ATOM 5601 O OH . TYR B 1 324 ? -39.312 43.798 -28.211 1.00 64.28 ? 322 TYR B OH 1 ATOM 5602 N N . PRO B 1 325 ? -40.043 47.623 -21.496 1.00 46.99 ? 323 PRO B N 1 ATOM 5603 C CA . PRO B 1 325 ? -40.538 46.618 -20.526 1.00 46.59 ? 323 PRO B CA 1 ATOM 5604 C C . PRO B 1 325 ? -41.514 45.627 -21.186 1.00 48.42 ? 323 PRO B C 1 ATOM 5605 O O . PRO B 1 325 ? -42.011 45.886 -22.279 1.00 46.32 ? 323 PRO B O 1 ATOM 5606 C CB . PRO B 1 325 ? -41.266 47.475 -19.490 1.00 47.95 ? 323 PRO B CB 1 ATOM 5607 C CG . PRO B 1 325 ? -41.820 48.605 -20.307 1.00 52.12 ? 323 PRO B CG 1 ATOM 5608 C CD . PRO B 1 325 ? -40.682 48.935 -21.265 1.00 47.84 ? 323 PRO B CD 1 ATOM 5609 N N . ILE B 1 326 ? -41.769 44.496 -20.520 1.00 46.82 ? 324 ILE B N 1 ATOM 5610 C CA . ILE B 1 326 ? -42.717 43.454 -20.931 1.00 47.24 ? 324 ILE B CA 1 ATOM 5611 C C . ILE B 1 326 ? -43.780 43.285 -19.801 1.00 54.40 ? 324 ILE B C 1 ATOM 5612 O O . ILE B 1 326 ? -43.486 42.751 -18.717 1.00 54.51 ? 324 ILE B O 1 ATOM 5613 C CB . ILE B 1 326 ? -41.986 42.136 -21.314 1.00 50.06 ? 324 ILE B CB 1 ATOM 5614 C CG1 . ILE B 1 326 ? -41.038 42.339 -22.515 1.00 50.13 ? 324 ILE B CG1 1 ATOM 5615 C CG2 . ILE B 1 326 ? -42.982 41.006 -21.587 1.00 51.84 ? 324 ILE B CG2 1 ATOM 5616 C CD1 . ILE B 1 326 ? -39.786 41.371 -22.536 1.00 56.78 ? 324 ILE B CD1 1 ATOM 5617 N N . SER B 1 327 ? -45.005 43.773 -20.047 1.00 53.22 ? 325 SER B N 1 ATOM 5618 C CA . SER B 1 327 ? -46.092 43.701 -19.049 1.00 53.62 ? 325 SER B CA 1 ATOM 5619 C C . SER B 1 327 ? -46.446 42.266 -18.660 1.00 56.21 ? 325 SER B C 1 ATOM 5620 O O . SER B 1 327 ? -46.704 42.013 -17.486 1.00 56.46 ? 325 SER B O 1 ATOM 5621 C CB . SER B 1 327 ? -47.320 44.488 -19.505 1.00 57.39 ? 325 SER B CB 1 ATOM 5622 O OG . SER B 1 327 ? -48.418 44.421 -18.608 1.00 69.20 ? 325 SER B OG 1 ATOM 5623 N N . ASP B 1 328 ? -46.423 41.333 -19.623 1.00 51.76 ? 326 ASP B N 1 ATOM 5624 C CA . ASP B 1 328 ? -46.698 39.929 -19.331 1.00 51.90 ? 326 ASP B CA 1 ATOM 5625 C C . ASP B 1 328 ? -45.650 39.347 -18.393 1.00 55.03 ? 326 ASP B C 1 ATOM 5626 O O . ASP B 1 328 ? -46.017 38.542 -17.542 1.00 56.42 ? 326 ASP B O 1 ATOM 5627 C CB . ASP B 1 328 ? -46.839 39.078 -20.607 1.00 54.46 ? 326 ASP B CB 1 ATOM 5628 C CG . ASP B 1 328 ? -48.181 39.205 -21.322 1.00 72.70 ? 326 ASP B CG 1 ATOM 5629 O OD1 . ASP B 1 328 ? -49.219 39.400 -20.627 1.00 76.01 ? 326 ASP B OD1 1 ATOM 5630 O OD2 . ASP B 1 328 ? -48.204 39.080 -22.571 1.00 78.09 ? 326 ASP B OD2 1 ATOM 5631 N N . PHE B 1 329 ? -44.366 39.798 -18.496 1.00 48.26 ? 327 PHE B N 1 ATOM 5632 C CA . PHE B 1 329 ? -43.300 39.303 -17.621 1.00 46.35 ? 327 PHE B CA 1 ATOM 5633 C C . PHE B 1 329 ? -43.437 39.788 -16.180 1.00 51.78 ? 327 PHE B C 1 ATOM 5634 O O . PHE B 1 329 ? -43.199 38.986 -15.274 1.00 51.89 ? 327 PHE B O 1 ATOM 5635 C CB . PHE B 1 329 ? -41.894 39.576 -18.174 1.00 46.25 ? 327 PHE B CB 1 ATOM 5636 C CG . PHE B 1 329 ? -40.785 39.088 -17.270 1.00 44.47 ? 327 PHE B CG 1 ATOM 5637 C CD1 . PHE B 1 329 ? -40.575 37.726 -17.072 1.00 44.36 ? 327 PHE B CD1 1 ATOM 5638 C CD2 . PHE B 1 329 ? -39.970 39.989 -16.594 1.00 43.98 ? 327 PHE B CD2 1 ATOM 5639 C CE1 . PHE B 1 329 ? -39.575 37.279 -16.211 1.00 43.23 ? 327 PHE B CE1 1 ATOM 5640 C CE2 . PHE B 1 329 ? -38.953 39.537 -15.754 1.00 45.40 ? 327 PHE B CE2 1 ATOM 5641 C CZ . PHE B 1 329 ? -38.759 38.183 -15.579 1.00 42.54 ? 327 PHE B CZ 1 ATOM 5642 N N . ALA B 1 330 ? -43.794 41.078 -15.967 1.00 49.45 ? 328 ALA B N 1 ATOM 5643 C CA . ALA B 1 330 ? -44.070 41.657 -14.631 1.00 49.92 ? 328 ALA B CA 1 ATOM 5644 C C . ALA B 1 330 ? -45.136 40.827 -13.881 1.00 53.91 ? 328 ALA B C 1 ATOM 5645 O O . ALA B 1 330 ? -44.919 40.452 -12.731 1.00 53.16 ? 328 ALA B O 1 ATOM 5646 C CB . ALA B 1 330 ? -44.557 43.094 -14.763 1.00 50.46 ? 328 ALA B CB 1 ATOM 5647 N N . SER B 1 331 ? -46.250 40.513 -14.560 1.00 51.48 ? 329 SER B N 1 ATOM 5648 C CA . SER B 1 331 ? -47.357 39.711 -14.044 1.00 52.95 ? 329 SER B CA 1 ATOM 5649 C C . SER B 1 331 ? -46.847 38.325 -13.654 1.00 56.78 ? 329 SER B C 1 ATOM 5650 O O . SER B 1 331 ? -47.176 37.827 -12.581 1.00 58.22 ? 329 SER B O 1 ATOM 5651 C CB . SER B 1 331 ? -48.454 39.573 -15.107 1.00 59.44 ? 329 SER B CB 1 ATOM 5652 O OG . SER B 1 331 ? -48.852 40.818 -15.665 1.00 70.26 ? 329 SER B OG 1 ATOM 5653 N N . TYR B 1 332 ? -46.032 37.718 -14.525 1.00 50.76 ? 330 TYR B N 1 ATOM 5654 C CA . TYR B 1 332 ? -45.434 36.406 -14.319 1.00 49.65 ? 330 TYR B CA 1 ATOM 5655 C C . TYR B 1 332 ? -44.533 36.392 -13.055 1.00 52.40 ? 330 TYR B C 1 ATOM 5656 O O . TYR B 1 332 ? -44.660 35.511 -12.197 1.00 51.48 ? 330 TYR B O 1 ATOM 5657 C CB . TYR B 1 332 ? -44.635 36.011 -15.580 1.00 49.62 ? 330 TYR B CB 1 ATOM 5658 C CG . TYR B 1 332 ? -43.713 34.832 -15.369 1.00 49.29 ? 330 TYR B CG 1 ATOM 5659 C CD1 . TYR B 1 332 ? -44.196 33.529 -15.420 1.00 50.17 ? 330 TYR B CD1 1 ATOM 5660 C CD2 . TYR B 1 332 ? -42.360 35.019 -15.085 1.00 49.27 ? 330 TYR B CD2 1 ATOM 5661 C CE1 . TYR B 1 332 ? -43.352 32.437 -15.215 1.00 49.33 ? 330 TYR B CE1 1 ATOM 5662 C CE2 . TYR B 1 332 ? -41.513 33.932 -14.852 1.00 49.34 ? 330 TYR B CE2 1 ATOM 5663 C CZ . TYR B 1 332 ? -42.016 32.643 -14.918 1.00 53.68 ? 330 TYR B CZ 1 ATOM 5664 O OH . TYR B 1 332 ? -41.209 31.556 -14.694 1.00 55.62 ? 330 TYR B OH 1 ATOM 5665 N N . PHE B 1 333 ? -43.609 37.351 -12.976 1.00 48.05 ? 331 PHE B N 1 ATOM 5666 C CA . PHE B 1 333 ? -42.645 37.441 -11.892 1.00 46.85 ? 331 PHE B CA 1 ATOM 5667 C C . PHE B 1 333 ? -43.285 37.683 -10.538 1.00 50.96 ? 331 PHE B C 1 ATOM 5668 O O . PHE B 1 333 ? -42.909 37.040 -9.554 1.00 48.37 ? 331 PHE B O 1 ATOM 5669 C CB . PHE B 1 333 ? -41.572 38.494 -12.196 1.00 47.72 ? 331 PHE B CB 1 ATOM 5670 C CG . PHE B 1 333 ? -40.354 38.276 -11.336 1.00 48.78 ? 331 PHE B CG 1 ATOM 5671 C CD1 . PHE B 1 333 ? -39.378 37.361 -11.707 1.00 51.03 ? 331 PHE B CD1 1 ATOM 5672 C CD2 . PHE B 1 333 ? -40.204 38.950 -10.129 1.00 50.23 ? 331 PHE B CD2 1 ATOM 5673 C CE1 . PHE B 1 333 ? -38.274 37.135 -10.894 1.00 51.83 ? 331 PHE B CE1 1 ATOM 5674 C CE2 . PHE B 1 333 ? -39.094 38.738 -9.330 1.00 52.43 ? 331 PHE B CE2 1 ATOM 5675 C CZ . PHE B 1 333 ? -38.136 37.828 -9.716 1.00 50.84 ? 331 PHE B CZ 1 ATOM 5676 N N . GLN B 1 334 ? -44.274 38.608 -10.506 1.00 48.91 ? 332 GLN B N 1 ATOM 5677 C CA . GLN B 1 334 ? -45.005 39.010 -9.312 1.00 47.34 ? 332 GLN B CA 1 ATOM 5678 C C . GLN B 1 334 ? -45.911 37.901 -8.793 1.00 49.65 ? 332 GLN B C 1 ATOM 5679 O O . GLN B 1 334 ? -46.222 37.871 -7.613 1.00 50.35 ? 332 GLN B O 1 ATOM 5680 C CB . GLN B 1 334 ? -45.760 40.314 -9.556 1.00 48.54 ? 332 GLN B CB 1 ATOM 5681 C CG . GLN B 1 334 ? -44.846 41.548 -9.611 1.00 64.07 ? 332 GLN B CG 1 ATOM 5682 C CD . GLN B 1 334 ? -45.632 42.815 -9.355 1.00 90.61 ? 332 GLN B CD 1 ATOM 5683 O OE1 . GLN B 1 334 ? -46.406 43.280 -10.202 1.00 89.76 ? 332 GLN B OE1 1 ATOM 5684 N NE2 . GLN B 1 334 ? -45.469 43.401 -8.175 1.00 80.49 ? 332 GLN B NE2 1 ATOM 5685 N N . SER B 1 335 ? -46.289 36.969 -9.644 1.00 45.45 ? 333 SER B N 1 ATOM 5686 C CA . SER B 1 335 ? -47.129 35.858 -9.225 1.00 45.44 ? 333 SER B CA 1 ATOM 5687 C C . SER B 1 335 ? -46.302 34.637 -8.729 1.00 48.07 ? 333 SER B C 1 ATOM 5688 O O . SER B 1 335 ? -46.901 33.621 -8.358 1.00 45.97 ? 333 SER B O 1 ATOM 5689 C CB . SER B 1 335 ? -48.090 35.471 -10.346 1.00 49.14 ? 333 SER B CB 1 ATOM 5690 O OG . SER B 1 335 ? -47.394 35.016 -11.496 1.00 62.45 ? 333 SER B OG 1 ATOM 5691 N N . LEU B 1 336 ? -44.937 34.746 -8.701 1.00 43.92 ? 334 LEU B N 1 ATOM 5692 C CA . LEU B 1 336 ? -44.074 33.633 -8.254 1.00 43.18 ? 334 LEU B CA 1 ATOM 5693 C C . LEU B 1 336 ? -44.019 33.549 -6.732 1.00 50.51 ? 334 LEU B C 1 ATOM 5694 O O . LEU B 1 336 ? -43.925 34.574 -6.054 1.00 51.78 ? 334 LEU B O 1 ATOM 5695 C CB . LEU B 1 336 ? -42.638 33.702 -8.824 1.00 42.24 ? 334 LEU B CB 1 ATOM 5696 C CG . LEU B 1 336 ? -42.431 33.798 -10.331 1.00 46.08 ? 334 LEU B CG 1 ATOM 5697 C CD1 . LEU B 1 336 ? -41.007 34.180 -10.641 1.00 45.38 ? 334 LEU B CD1 1 ATOM 5698 C CD2 . LEU B 1 336 ? -42.786 32.504 -11.038 1.00 47.57 ? 334 LEU B CD2 1 ATOM 5699 N N . ASP B 1 337 ? -44.051 32.324 -6.199 1.00 48.24 ? 335 ASP B N 1 ATOM 5700 C CA . ASP B 1 337 ? -44.010 32.062 -4.760 1.00 48.17 ? 335 ASP B CA 1 ATOM 5701 C C . ASP B 1 337 ? -43.190 30.795 -4.437 1.00 51.83 ? 335 ASP B C 1 ATOM 5702 O O . ASP B 1 337 ? -43.103 29.913 -5.287 1.00 49.10 ? 335 ASP B O 1 ATOM 5703 C CB . ASP B 1 337 ? -45.424 32.047 -4.156 1.00 49.94 ? 335 ASP B CB 1 ATOM 5704 C CG . ASP B 1 337 ? -46.139 30.721 -4.222 1.00 64.39 ? 335 ASP B CG 1 ATOM 5705 O OD1 . ASP B 1 337 ? -45.790 29.814 -3.420 1.00 65.80 ? 335 ASP B OD1 1 ATOM 5706 O OD2 . ASP B 1 337 ? -47.100 30.610 -5.012 1.00 70.94 ? 335 ASP B OD2 1 ATOM 5707 N N . PRO B 1 338 ? -42.600 30.692 -3.216 1.00 51.55 ? 336 PRO B N 1 ATOM 5708 C CA . PRO B 1 338 ? -41.714 29.552 -2.895 1.00 52.44 ? 336 PRO B CA 1 ATOM 5709 C C . PRO B 1 338 ? -42.305 28.160 -2.962 1.00 59.08 ? 336 PRO B C 1 ATOM 5710 O O . PRO B 1 338 ? -41.574 27.189 -3.173 1.00 59.57 ? 336 PRO B O 1 ATOM 5711 C CB . PRO B 1 338 ? -41.288 29.841 -1.468 1.00 54.07 ? 336 PRO B CB 1 ATOM 5712 C CG . PRO B 1 338 ? -41.400 31.278 -1.336 1.00 58.14 ? 336 PRO B CG 1 ATOM 5713 C CD . PRO B 1 338 ? -42.590 31.674 -2.118 1.00 53.31 ? 336 PRO B CD 1 ATOM 5714 N N . TRP B 1 339 ? -43.610 28.065 -2.758 1.00 56.32 ? 337 TRP B N 1 ATOM 5715 C CA . TRP B 1 339 ? -44.319 26.805 -2.781 1.00 56.37 ? 337 TRP B CA 1 ATOM 5716 C C . TRP B 1 339 ? -44.731 26.425 -4.223 1.00 60.68 ? 337 TRP B C 1 ATOM 5717 O O . TRP B 1 339 ? -44.713 25.242 -4.558 1.00 61.88 ? 337 TRP B O 1 ATOM 5718 C CB . TRP B 1 339 ? -45.475 26.858 -1.764 1.00 55.26 ? 337 TRP B CB 1 ATOM 5719 C CG . TRP B 1 339 ? -44.947 27.053 -0.365 1.00 56.43 ? 337 TRP B CG 1 ATOM 5720 C CD1 . TRP B 1 339 ? -44.449 26.086 0.462 1.00 59.59 ? 337 TRP B CD1 1 ATOM 5721 C CD2 . TRP B 1 339 ? -44.706 28.304 0.295 1.00 56.17 ? 337 TRP B CD2 1 ATOM 5722 N NE1 . TRP B 1 339 ? -43.934 26.652 1.605 1.00 58.92 ? 337 TRP B NE1 1 ATOM 5723 C CE2 . TRP B 1 339 ? -44.083 28.012 1.533 1.00 60.22 ? 337 TRP B CE2 1 ATOM 5724 C CE3 . TRP B 1 339 ? -44.937 29.653 -0.047 1.00 57.35 ? 337 TRP B CE3 1 ATOM 5725 C CZ2 . TRP B 1 339 ? -43.689 29.016 2.431 1.00 59.56 ? 337 TRP B CZ2 1 ATOM 5726 C CZ3 . TRP B 1 339 ? -44.566 30.643 0.850 1.00 58.59 ? 337 TRP B CZ3 1 ATOM 5727 C CH2 . TRP B 1 339 ? -43.923 30.323 2.059 1.00 59.35 ? 337 TRP B CH2 1 ATOM 5728 N N . ASN B 1 340 ? -45.003 27.418 -5.099 1.00 54.70 ? 338 ASN B N 1 ATOM 5729 C CA . ASN B 1 340 ? -45.385 27.149 -6.495 1.00 53.16 ? 338 ASN B CA 1 ATOM 5730 C C . ASN B 1 340 ? -44.240 27.245 -7.508 1.00 53.11 ? 338 ASN B C 1 ATOM 5731 O O . ASN B 1 340 ? -44.444 26.890 -8.663 1.00 50.45 ? 338 ASN B O 1 ATOM 5732 C CB . ASN B 1 340 ? -46.553 28.044 -6.941 1.00 56.18 ? 338 ASN B CB 1 ATOM 5733 C CG . ASN B 1 340 ? -47.922 27.628 -6.435 1.00 97.59 ? 338 ASN B CG 1 ATOM 5734 O OD1 . ASN B 1 340 ? -48.273 26.433 -6.383 1.00 94.46 ? 338 ASN B OD1 1 ATOM 5735 N ND2 . ASN B 1 340 ? -48.755 28.618 -6.101 1.00 92.23 ? 338 ASN B ND2 1 ATOM 5736 N N . ASN B 1 341 ? -43.044 27.727 -7.100 1.00 49.15 ? 339 ASN B N 1 ATOM 5737 C CA . ASN B 1 341 ? -41.916 27.858 -8.029 1.00 47.51 ? 339 ASN B CA 1 ATOM 5738 C C . ASN B 1 341 ? -40.769 26.859 -7.726 1.00 50.03 ? 339 ASN B C 1 ATOM 5739 O O . ASN B 1 341 ? -39.583 27.166 -7.939 1.00 51.40 ? 339 ASN B O 1 ATOM 5740 C CB . ASN B 1 341 ? -41.430 29.314 -8.106 1.00 42.02 ? 339 ASN B CB 1 ATOM 5741 C CG . ASN B 1 341 ? -40.547 29.618 -9.288 1.00 56.89 ? 339 ASN B CG 1 ATOM 5742 O OD1 . ASN B 1 341 ? -40.366 28.794 -10.192 1.00 50.36 ? 339 ASN B OD1 1 ATOM 5743 N ND2 . ASN B 1 341 ? -39.934 30.792 -9.279 1.00 48.65 ? 339 ASN B ND2 1 ATOM 5744 N N . SER B 1 342 ? -41.132 25.642 -7.305 1.00 43.15 ? 340 SER B N 1 ATOM 5745 C CA . SER B 1 342 ? -40.174 24.579 -6.990 1.00 43.22 ? 340 SER B CA 1 ATOM 5746 C C . SER B 1 342 ? -39.082 24.355 -8.070 1.00 48.49 ? 340 SER B C 1 ATOM 5747 O O . SER B 1 342 ? -37.931 24.015 -7.724 1.00 47.95 ? 340 SER B O 1 ATOM 5748 C CB . SER B 1 342 ? -40.905 23.269 -6.728 1.00 45.93 ? 340 SER B CB 1 ATOM 5749 O OG . SER B 1 342 ? -41.436 22.759 -7.939 1.00 58.33 ? 340 SER B OG 1 ATOM 5750 N N . ARG B 1 343 ? -39.458 24.556 -9.367 1.00 43.63 ? 341 ARG B N 1 ATOM 5751 C CA . ARG B 1 343 ? -38.595 24.335 -10.526 1.00 42.62 ? 341 ARG B CA 1 ATOM 5752 C C . ARG B 1 343 ? -37.370 25.234 -10.536 1.00 46.71 ? 341 ARG B C 1 ATOM 5753 O O . ARG B 1 343 ? -36.407 24.920 -11.238 1.00 47.54 ? 341 ARG B O 1 ATOM 5754 C CB . ARG B 1 343 ? -39.373 24.405 -11.852 1.00 41.59 ? 341 ARG B CB 1 ATOM 5755 C CG . ARG B 1 343 ? -39.704 25.803 -12.340 1.00 39.66 ? 341 ARG B CG 1 ATOM 5756 C CD . ARG B 1 343 ? -40.331 25.792 -13.736 1.00 35.99 ? 341 ARG B CD 1 ATOM 5757 N NE . ARG B 1 343 ? -40.737 27.158 -14.063 1.00 36.64 ? 341 ARG B NE 1 ATOM 5758 C CZ . ARG B 1 343 ? -41.245 27.556 -15.220 1.00 49.87 ? 341 ARG B CZ 1 ATOM 5759 N NH1 . ARG B 1 343 ? -41.436 26.683 -16.204 1.00 25.32 ? 341 ARG B NH1 1 ATOM 5760 N NH2 . ARG B 1 343 ? -41.555 28.840 -15.411 1.00 32.59 ? 341 ARG B NH2 1 ATOM 5761 N N . ASN B 1 344 ? -37.392 26.344 -9.768 1.00 41.09 ? 342 ASN B N 1 ATOM 5762 C CA . ASN B 1 344 ? -36.215 27.183 -9.645 1.00 38.80 ? 342 ASN B CA 1 ATOM 5763 C C . ASN B 1 344 ? -35.485 26.748 -8.359 1.00 43.74 ? 342 ASN B C 1 ATOM 5764 O O . ASN B 1 344 ? -36.005 26.975 -7.248 1.00 43.53 ? 342 ASN B O 1 ATOM 5765 C CB . ASN B 1 344 ? -36.567 28.657 -9.645 1.00 30.56 ? 342 ASN B CB 1 ATOM 5766 C CG . ASN B 1 344 ? -35.330 29.526 -9.581 1.00 43.25 ? 342 ASN B CG 1 ATOM 5767 O OD1 . ASN B 1 344 ? -34.189 29.054 -9.421 1.00 39.51 ? 342 ASN B OD1 1 ATOM 5768 N ND2 . ASN B 1 344 ? -35.518 30.813 -9.734 1.00 26.58 ? 342 ASN B ND2 1 ATOM 5769 N N . PRO B 1 345 ? -34.305 26.083 -8.483 1.00 40.02 ? 343 PRO B N 1 ATOM 5770 C CA . PRO B 1 345 ? -33.589 25.600 -7.278 1.00 39.41 ? 343 PRO B CA 1 ATOM 5771 C C . PRO B 1 345 ? -33.128 26.703 -6.329 1.00 44.85 ? 343 PRO B C 1 ATOM 5772 O O . PRO B 1 345 ? -32.919 26.460 -5.140 1.00 44.38 ? 343 PRO B O 1 ATOM 5773 C CB . PRO B 1 345 ? -32.385 24.833 -7.854 1.00 40.67 ? 343 PRO B CB 1 ATOM 5774 C CG . PRO B 1 345 ? -32.187 25.355 -9.204 1.00 44.90 ? 343 PRO B CG 1 ATOM 5775 C CD . PRO B 1 345 ? -33.573 25.719 -9.708 1.00 41.25 ? 343 PRO B CD 1 ATOM 5776 N N . TRP B 1 346 ? -33.011 27.925 -6.859 1.00 42.21 ? 344 TRP B N 1 ATOM 5777 C CA . TRP B 1 346 ? -32.539 29.096 -6.141 1.00 41.58 ? 344 TRP B CA 1 ATOM 5778 C C . TRP B 1 346 ? -33.606 30.055 -5.620 1.00 45.66 ? 344 TRP B C 1 ATOM 5779 O O . TRP B 1 346 ? -33.260 30.970 -4.872 1.00 45.75 ? 344 TRP B O 1 ATOM 5780 C CB . TRP B 1 346 ? -31.582 29.853 -7.052 1.00 39.68 ? 344 TRP B CB 1 ATOM 5781 C CG . TRP B 1 346 ? -30.399 29.042 -7.461 1.00 40.18 ? 344 TRP B CG 1 ATOM 5782 C CD1 . TRP B 1 346 ? -29.346 28.668 -6.677 1.00 43.08 ? 344 TRP B CD1 1 ATOM 5783 C CD2 . TRP B 1 346 ? -30.113 28.558 -8.778 1.00 39.80 ? 344 TRP B CD2 1 ATOM 5784 N NE1 . TRP B 1 346 ? -28.424 27.964 -7.424 1.00 42.54 ? 344 TRP B NE1 1 ATOM 5785 C CE2 . TRP B 1 346 ? -28.855 27.910 -8.724 1.00 43.51 ? 344 TRP B CE2 1 ATOM 5786 C CE3 . TRP B 1 346 ? -30.774 28.643 -10.009 1.00 40.49 ? 344 TRP B CE3 1 ATOM 5787 C CZ2 . TRP B 1 346 ? -28.250 27.368 -9.852 1.00 41.87 ? 344 TRP B CZ2 1 ATOM 5788 C CZ3 . TRP B 1 346 ? -30.185 28.065 -11.116 1.00 41.24 ? 344 TRP B CZ3 1 ATOM 5789 C CH2 . TRP B 1 346 ? -28.935 27.447 -11.032 1.00 41.62 ? 344 TRP B CH2 1 ATOM 5790 N N . PHE B 1 347 ? -34.875 29.879 -6.007 1.00 42.12 ? 345 PHE B N 1 ATOM 5791 C CA . PHE B 1 347 ? -35.941 30.800 -5.615 1.00 41.58 ? 345 PHE B CA 1 ATOM 5792 C C . PHE B 1 347 ? -36.150 30.915 -4.095 1.00 45.87 ? 345 PHE B C 1 ATOM 5793 O O . PHE B 1 347 ? -36.314 32.039 -3.602 1.00 47.25 ? 345 PHE B O 1 ATOM 5794 C CB . PHE B 1 347 ? -37.234 30.451 -6.334 1.00 43.41 ? 345 PHE B CB 1 ATOM 5795 C CG . PHE B 1 347 ? -38.261 31.548 -6.319 1.00 45.33 ? 345 PHE B CG 1 ATOM 5796 C CD1 . PHE B 1 347 ? -38.134 32.658 -7.161 1.00 49.06 ? 345 PHE B CD1 1 ATOM 5797 C CD2 . PHE B 1 347 ? -39.354 31.485 -5.459 1.00 46.53 ? 345 PHE B CD2 1 ATOM 5798 C CE1 . PHE B 1 347 ? -39.091 33.679 -7.150 1.00 50.22 ? 345 PHE B CE1 1 ATOM 5799 C CE2 . PHE B 1 347 ? -40.307 32.508 -5.443 1.00 50.38 ? 345 PHE B CE2 1 ATOM 5800 C CZ . PHE B 1 347 ? -40.171 33.601 -6.283 1.00 49.04 ? 345 PHE B CZ 1 ATOM 5801 N N . ARG B 1 348 ? -36.106 29.786 -3.347 1.00 40.45 ? 346 ARG B N 1 ATOM 5802 C CA . ARG B 1 348 ? -36.225 29.821 -1.880 1.00 40.48 ? 346 ARG B CA 1 ATOM 5803 C C . ARG B 1 348 ? -35.069 30.657 -1.236 1.00 44.42 ? 346 ARG B C 1 ATOM 5804 O O . ARG B 1 348 ? -35.304 31.400 -0.278 1.00 44.42 ? 346 ARG B O 1 ATOM 5805 C CB . ARG B 1 348 ? -36.293 28.403 -1.289 1.00 42.02 ? 346 ARG B CB 1 ATOM 5806 C CG . ARG B 1 348 ? -37.702 27.814 -1.371 1.00 55.79 ? 346 ARG B CG 1 ATOM 5807 C CD . ARG B 1 348 ? -37.755 26.348 -0.981 1.00 63.37 ? 346 ARG B CD 1 ATOM 5808 N NE . ARG B 1 348 ? -38.221 26.178 0.392 1.00 72.72 ? 346 ARG B NE 1 ATOM 5809 C CZ . ARG B 1 348 ? -39.488 25.999 0.744 1.00 82.36 ? 346 ARG B CZ 1 ATOM 5810 N NH1 . ARG B 1 348 ? -39.816 25.888 2.026 1.00 74.92 ? 346 ARG B NH1 1 ATOM 5811 N NH2 . ARG B 1 348 ? -40.435 25.915 -0.181 1.00 62.62 ? 346 ARG B NH2 1 ATOM 5812 N N . GLU B 1 349 ? -33.839 30.573 -1.805 1.00 38.26 ? 347 GLU B N 1 ATOM 5813 C CA . GLU B 1 349 ? -32.706 31.345 -1.333 1.00 36.87 ? 347 GLU B CA 1 ATOM 5814 C C . GLU B 1 349 ? -32.919 32.829 -1.674 1.00 43.55 ? 347 GLU B C 1 ATOM 5815 O O . GLU B 1 349 ? -32.711 33.682 -0.814 1.00 44.43 ? 347 GLU B O 1 ATOM 5816 C CB . GLU B 1 349 ? -31.425 30.812 -1.940 1.00 37.97 ? 347 GLU B CB 1 ATOM 5817 C CG . GLU B 1 349 ? -30.203 31.115 -1.103 1.00 47.99 ? 347 GLU B CG 1 ATOM 5818 C CD . GLU B 1 349 ? -28.937 31.304 -1.908 1.00 74.69 ? 347 GLU B CD 1 ATOM 5819 O OE1 . GLU B 1 349 ? -28.118 32.178 -1.529 1.00 75.69 ? 347 GLU B OE1 1 ATOM 5820 O OE2 . GLU B 1 349 ? -28.789 30.614 -2.946 1.00 50.73 ? 347 GLU B OE2 1 ATOM 5821 N N . PHE B 1 350 ? -33.367 33.142 -2.902 1.00 40.43 ? 348 PHE B N 1 ATOM 5822 C CA . PHE B 1 350 ? -33.688 34.517 -3.271 1.00 40.63 ? 348 PHE B CA 1 ATOM 5823 C C . PHE B 1 350 ? -34.692 35.103 -2.242 1.00 47.30 ? 348 PHE B C 1 ATOM 5824 O O . PHE B 1 350 ? -34.452 36.182 -1.717 1.00 46.91 ? 348 PHE B O 1 ATOM 5825 C CB . PHE B 1 350 ? -34.285 34.580 -4.701 1.00 41.82 ? 348 PHE B CB 1 ATOM 5826 C CG . PHE B 1 350 ? -35.254 35.722 -4.966 1.00 41.47 ? 348 PHE B CG 1 ATOM 5827 C CD1 . PHE B 1 350 ? -34.797 37.036 -5.085 1.00 43.35 ? 348 PHE B CD1 1 ATOM 5828 C CD2 . PHE B 1 350 ? -36.619 35.481 -5.100 1.00 40.37 ? 348 PHE B CD2 1 ATOM 5829 C CE1 . PHE B 1 350 ? -35.697 38.090 -5.320 1.00 43.30 ? 348 PHE B CE1 1 ATOM 5830 C CE2 . PHE B 1 350 ? -37.509 36.531 -5.345 1.00 42.50 ? 348 PHE B CE2 1 ATOM 5831 C CZ . PHE B 1 350 ? -37.044 37.825 -5.463 1.00 40.95 ? 348 PHE B CZ 1 ATOM 5832 N N . TRP B 1 351 ? -35.774 34.350 -1.938 1.00 45.27 ? 349 TRP B N 1 ATOM 5833 C CA . TRP B 1 351 ? -36.870 34.731 -1.049 1.00 45.25 ? 349 TRP B CA 1 ATOM 5834 C C . TRP B 1 351 ? -36.413 35.056 0.380 1.00 47.73 ? 349 TRP B C 1 ATOM 5835 O O . TRP B 1 351 ? -36.702 36.149 0.874 1.00 46.03 ? 349 TRP B O 1 ATOM 5836 C CB . TRP B 1 351 ? -37.938 33.648 -1.085 1.00 44.63 ? 349 TRP B CB 1 ATOM 5837 C CG . TRP B 1 351 ? -39.278 34.064 -0.563 1.00 46.34 ? 349 TRP B CG 1 ATOM 5838 C CD1 . TRP B 1 351 ? -39.714 33.980 0.730 1.00 49.39 ? 349 TRP B CD1 1 ATOM 5839 C CD2 . TRP B 1 351 ? -40.404 34.503 -1.338 1.00 46.15 ? 349 TRP B CD2 1 ATOM 5840 N NE1 . TRP B 1 351 ? -41.043 34.339 0.806 1.00 48.50 ? 349 TRP B NE1 1 ATOM 5841 C CE2 . TRP B 1 351 ? -41.489 34.671 -0.447 1.00 49.84 ? 349 TRP B CE2 1 ATOM 5842 C CE3 . TRP B 1 351 ? -40.606 34.761 -2.703 1.00 47.60 ? 349 TRP B CE3 1 ATOM 5843 C CZ2 . TRP B 1 351 ? -42.743 35.122 -0.872 1.00 49.13 ? 349 TRP B CZ2 1 ATOM 5844 C CZ3 . TRP B 1 351 ? -41.869 35.148 -3.132 1.00 49.09 ? 349 TRP B CZ3 1 ATOM 5845 C CH2 . TRP B 1 351 ? -42.913 35.345 -2.222 1.00 49.58 ? 349 TRP B CH2 1 ATOM 5846 N N . GLU B 1 352 ? -35.638 34.146 1.013 1.00 43.70 ? 350 GLU B N 1 ATOM 5847 C CA . GLU B 1 352 ? -35.072 34.371 2.361 1.00 41.78 ? 350 GLU B CA 1 ATOM 5848 C C . GLU B 1 352 ? -34.291 35.680 2.380 1.00 43.26 ? 350 GLU B C 1 ATOM 5849 O O . GLU B 1 352 ? -34.545 36.497 3.232 1.00 41.49 ? 350 GLU B O 1 ATOM 5850 C CB . GLU B 1 352 ? -34.179 33.196 2.810 1.00 42.32 ? 350 GLU B CB 1 ATOM 5851 C CG . GLU B 1 352 ? -34.948 31.898 3.004 1.00 48.72 ? 350 GLU B CG 1 ATOM 5852 C CD . GLU B 1 352 ? -34.236 30.736 3.665 1.00 59.79 ? 350 GLU B CD 1 ATOM 5853 O OE1 . GLU B 1 352 ? -34.912 29.957 4.373 1.00 51.56 ? 350 GLU B OE1 1 ATOM 5854 O OE2 . GLU B 1 352 ? -33.007 30.597 3.479 1.00 54.46 ? 350 GLU B OE2 1 ATOM 5855 N N . GLN B 1 353 ? -33.410 35.897 1.393 1.00 41.44 ? 351 GLN B N 1 ATOM 5856 C CA . GLN B 1 353 ? -32.596 37.101 1.224 1.00 42.45 ? 351 GLN B CA 1 ATOM 5857 C C . GLN B 1 353 ? -33.485 38.354 1.015 1.00 48.84 ? 351 GLN B C 1 ATOM 5858 O O . GLN B 1 353 ? -33.331 39.340 1.746 1.00 47.82 ? 351 GLN B O 1 ATOM 5859 C CB . GLN B 1 353 ? -31.627 36.934 0.030 1.00 43.50 ? 351 GLN B CB 1 ATOM 5860 C CG . GLN B 1 353 ? -30.763 38.182 -0.226 1.00 58.60 ? 351 GLN B CG 1 ATOM 5861 C CD . GLN B 1 353 ? -29.671 38.011 -1.256 1.00 69.93 ? 351 GLN B CD 1 ATOM 5862 O OE1 . GLN B 1 353 ? -28.878 37.053 -1.231 1.00 64.70 ? 351 GLN B OE1 1 ATOM 5863 N NE2 . GLN B 1 353 ? -29.558 38.996 -2.129 1.00 51.91 ? 351 GLN B NE2 1 ATOM 5864 N N . ARG B 1 354 ? -34.388 38.299 0.000 1.00 45.65 ? 352 ARG B N 1 ATOM 5865 C CA . ARG B 1 354 ? -35.325 39.359 -0.399 1.00 44.75 ? 352 ARG B CA 1 ATOM 5866 C C . ARG B 1 354 ? -36.223 39.789 0.762 1.00 46.81 ? 352 ARG B C 1 ATOM 5867 O O . ARG B 1 354 ? -36.325 40.977 1.020 1.00 45.72 ? 352 ARG B O 1 ATOM 5868 C CB . ARG B 1 354 ? -36.145 38.955 -1.685 1.00 41.09 ? 352 ARG B CB 1 ATOM 5869 C CG . ARG B 1 354 ? -37.276 39.901 -2.135 1.00 41.88 ? 352 ARG B CG 1 ATOM 5870 C CD . ARG B 1 354 ? -36.785 41.325 -2.447 1.00 48.77 ? 352 ARG B CD 1 ATOM 5871 N NE . ARG B 1 354 ? -37.871 42.301 -2.569 1.00 53.35 ? 352 ARG B NE 1 ATOM 5872 C CZ . ARG B 1 354 ? -38.403 42.972 -1.547 1.00 65.97 ? 352 ARG B CZ 1 ATOM 5873 N NH1 . ARG B 1 354 ? -39.393 43.836 -1.753 1.00 44.01 ? 352 ARG B NH1 1 ATOM 5874 N NH2 . ARG B 1 354 ? -37.972 42.762 -0.307 1.00 52.25 ? 352 ARG B NH2 1 ATOM 5875 N N . PHE B 1 355 ? -36.808 38.827 1.482 1.00 44.07 ? 353 PHE B N 1 ATOM 5876 C CA . PHE B 1 355 ? -37.729 39.081 2.591 1.00 44.20 ? 353 PHE B CA 1 ATOM 5877 C C . PHE B 1 355 ? -37.143 38.851 4.003 1.00 49.62 ? 353 PHE B C 1 ATOM 5878 O O . PHE B 1 355 ? -37.904 38.625 4.954 1.00 47.78 ? 353 PHE B O 1 ATOM 5879 C CB . PHE B 1 355 ? -39.001 38.262 2.391 1.00 45.45 ? 353 PHE B CB 1 ATOM 5880 C CG . PHE B 1 355 ? -39.785 38.668 1.169 1.00 46.77 ? 353 PHE B CG 1 ATOM 5881 C CD1 . PHE B 1 355 ? -40.310 39.953 1.051 1.00 48.68 ? 353 PHE B CD1 1 ATOM 5882 C CD2 . PHE B 1 355 ? -40.000 37.766 0.129 1.00 48.65 ? 353 PHE B CD2 1 ATOM 5883 C CE1 . PHE B 1 355 ? -41.062 40.318 -0.078 1.00 49.47 ? 353 PHE B CE1 1 ATOM 5884 C CE2 . PHE B 1 355 ? -40.748 38.135 -1.001 1.00 50.58 ? 353 PHE B CE2 1 ATOM 5885 C CZ . PHE B 1 355 ? -41.288 39.400 -1.087 1.00 48.29 ? 353 PHE B CZ 1 ATOM 5886 N N . ARG B 1 356 ? -35.789 38.953 4.141 1.00 47.58 ? 354 ARG B N 1 ATOM 5887 C CA . ARG B 1 356 ? -35.034 38.784 5.402 1.00 47.23 ? 354 ARG B CA 1 ATOM 5888 C C . ARG B 1 356 ? -35.731 37.791 6.358 1.00 51.06 ? 354 ARG B C 1 ATOM 5889 O O . ARG B 1 356 ? -35.955 38.092 7.534 1.00 51.94 ? 354 ARG B O 1 ATOM 5890 C CB . ARG B 1 356 ? -34.715 40.159 6.073 1.00 46.24 ? 354 ARG B CB 1 ATOM 5891 C CG . ARG B 1 356 ? -33.681 41.035 5.334 1.00 45.22 ? 354 ARG B CG 1 ATOM 5892 C CD . ARG B 1 356 ? -32.240 40.659 5.610 1.00 50.84 ? 354 ARG B CD 1 ATOM 5893 N NE . ARG B 1 356 ? -31.616 40.021 4.447 1.00 79.58 ? 354 ARG B NE 1 ATOM 5894 C CZ . ARG B 1 356 ? -30.748 40.614 3.626 1.00 103.74 ? 354 ARG B CZ 1 ATOM 5895 N NH1 . ARG B 1 356 ? -30.239 39.949 2.596 1.00 88.28 ? 354 ARG B NH1 1 ATOM 5896 N NH2 . ARG B 1 356 ? -30.374 41.872 3.837 1.00 96.78 ? 354 ARG B NH2 1 ATOM 5897 N N . CYS B 1 357 ? -36.120 36.620 5.807 1.00 48.19 ? 355 CYS B N 1 ATOM 5898 C CA . CYS B 1 357 ? -36.825 35.532 6.499 1.00 48.05 ? 355 CYS B CA 1 ATOM 5899 C C . CYS B 1 357 ? -36.070 34.214 6.418 1.00 48.92 ? 355 CYS B C 1 ATOM 5900 O O . CYS B 1 357 ? -34.963 34.172 5.886 1.00 49.67 ? 355 CYS B O 1 ATOM 5901 C CB . CYS B 1 357 ? -38.257 35.393 5.981 1.00 49.02 ? 355 CYS B CB 1 ATOM 5902 S SG . CYS B 1 357 ? -38.389 34.841 4.256 1.00 53.15 ? 355 CYS B SG 1 ATOM 5903 N N . SER B 1 358 ? -36.678 33.139 6.935 1.00 43.89 ? 356 SER B N 1 ATOM 5904 C CA . SER B 1 358 ? -36.130 31.777 6.927 1.00 43.00 ? 356 SER B CA 1 ATOM 5905 C C . SER B 1 358 ? -37.272 30.766 6.927 1.00 47.08 ? 356 SER B C 1 ATOM 5906 O O . SER B 1 358 ? -38.231 30.905 7.687 1.00 46.02 ? 356 SER B O 1 ATOM 5907 C CB . SER B 1 358 ? -35.190 31.551 8.105 1.00 45.01 ? 356 SER B CB 1 ATOM 5908 O OG . SER B 1 358 ? -34.689 30.225 8.135 1.00 53.46 ? 356 SER B OG 1 ATOM 5909 N N . PHE B 1 359 ? -37.175 29.779 6.029 1.00 44.92 ? 357 PHE B N 1 ATOM 5910 C CA . PHE B 1 359 ? -38.161 28.723 5.843 1.00 44.63 ? 357 PHE B CA 1 ATOM 5911 C C . PHE B 1 359 ? -38.207 27.786 7.013 1.00 48.57 ? 357 PHE B C 1 ATOM 5912 O O . PHE B 1 359 ? -39.291 27.305 7.349 1.00 50.26 ? 357 PHE B O 1 ATOM 5913 C CB . PHE B 1 359 ? -37.951 27.988 4.510 1.00 46.87 ? 357 PHE B CB 1 ATOM 5914 C CG . PHE B 1 359 ? -38.389 28.818 3.326 1.00 48.81 ? 357 PHE B CG 1 ATOM 5915 C CD1 . PHE B 1 359 ? -39.740 28.949 3.005 1.00 52.39 ? 357 PHE B CD1 1 ATOM 5916 C CD2 . PHE B 1 359 ? -37.458 29.493 2.551 1.00 50.49 ? 357 PHE B CD2 1 ATOM 5917 C CE1 . PHE B 1 359 ? -40.144 29.727 1.922 1.00 53.18 ? 357 PHE B CE1 1 ATOM 5918 C CE2 . PHE B 1 359 ? -37.861 30.272 1.470 1.00 53.69 ? 357 PHE B CE2 1 ATOM 5919 C CZ . PHE B 1 359 ? -39.199 30.411 1.182 1.00 52.19 ? 357 PHE B CZ 1 ATOM 5920 N N . ARG B 1 360 ? -37.057 27.583 7.678 1.00 44.65 ? 358 ARG B N 1 ATOM 5921 C CA . ARG B 1 360 ? -36.904 26.789 8.901 1.00 44.85 ? 358 ARG B CA 1 ATOM 5922 C C . ARG B 1 360 ? -37.759 27.450 9.983 1.00 50.14 ? 358 ARG B C 1 ATOM 5923 O O . ARG B 1 360 ? -38.636 26.793 10.541 1.00 50.95 ? 358 ARG B O 1 ATOM 5924 C CB . ARG B 1 360 ? -35.437 26.794 9.334 1.00 45.06 ? 358 ARG B CB 1 ATOM 5925 C CG . ARG B 1 360 ? -35.038 25.616 10.186 1.00 49.61 ? 358 ARG B CG 1 ATOM 5926 C CD . ARG B 1 360 ? -33.916 24.870 9.506 1.00 55.19 ? 358 ARG B CD 1 ATOM 5927 N NE . ARG B 1 360 ? -32.624 25.523 9.705 1.00 63.66 ? 358 ARG B NE 1 ATOM 5928 C CZ . ARG B 1 360 ? -31.477 25.082 9.198 1.00 78.04 ? 358 ARG B CZ 1 ATOM 5929 N NH1 . ARG B 1 360 ? -30.349 25.750 9.414 1.00 67.37 ? 358 ARG B NH1 1 ATOM 5930 N NH2 . ARG B 1 360 ? -31.446 23.966 8.478 1.00 56.23 ? 358 ARG B NH2 1 ATOM 5931 N N . GLN B 1 361 ? -37.570 28.783 10.168 1.00 46.38 ? 359 GLN B N 1 ATOM 5932 C CA . GLN B 1 361 ? -38.274 29.674 11.092 1.00 46.23 ? 359 GLN B CA 1 ATOM 5933 C C . GLN B 1 361 ? -39.766 29.832 10.821 1.00 51.28 ? 359 GLN B C 1 ATOM 5934 O O . GLN B 1 361 ? -40.500 30.270 11.711 1.00 51.15 ? 359 GLN B O 1 ATOM 5935 C CB . GLN B 1 361 ? -37.610 31.068 11.119 1.00 47.40 ? 359 GLN B CB 1 ATOM 5936 C CG . GLN B 1 361 ? -36.375 31.156 12.028 1.00 61.60 ? 359 GLN B CG 1 ATOM 5937 C CD . GLN B 1 361 ? -36.635 30.619 13.420 1.00 71.59 ? 359 GLN B CD 1 ATOM 5938 O OE1 . GLN B 1 361 ? -37.579 31.038 14.134 1.00 62.15 ? 359 GLN B OE1 1 ATOM 5939 N NE2 . GLN B 1 361 ? -35.864 29.606 13.783 1.00 52.93 ? 359 GLN B NE2 1 ATOM 5940 N N . ARG B 1 362 ? -40.191 29.561 9.574 1.00 48.77 ? 360 ARG B N 1 ATOM 5941 C CA . ARG B 1 362 ? -41.574 29.617 9.094 1.00 48.46 ? 360 ARG B CA 1 ATOM 5942 C C . ARG B 1 362 ? -42.131 31.062 9.071 1.00 52.94 ? 360 ARG B C 1 ATOM 5943 O O . ARG B 1 362 ? -43.350 31.270 9.173 1.00 54.15 ? 360 ARG B O 1 ATOM 5944 C CB . ARG B 1 362 ? -42.477 28.620 9.877 1.00 45.24 ? 360 ARG B CB 1 ATOM 5945 C CG . ARG B 1 362 ? -42.020 27.180 9.685 1.00 59.09 ? 360 ARG B CG 1 ATOM 5946 C CD . ARG B 1 362 ? -42.220 26.321 10.915 1.00 75.55 ? 360 ARG B CD 1 ATOM 5947 N NE . ARG B 1 362 ? -41.283 25.189 10.962 1.00 81.63 ? 360 ARG B NE 1 ATOM 5948 C CZ . ARG B 1 362 ? -41.450 24.106 11.720 1.00 94.24 ? 360 ARG B CZ 1 ATOM 5949 N NH1 . ARG B 1 362 ? -42.530 23.980 12.485 1.00 89.57 ? 360 ARG B NH1 1 ATOM 5950 N NH2 . ARG B 1 362 ? -40.547 23.133 11.704 1.00 69.78 ? 360 ARG B NH2 1 ATOM 5951 N N . ASP B 1 363 ? -41.251 32.051 8.856 1.00 47.77 ? 361 ASP B N 1 ATOM 5952 C CA . ASP B 1 363 ? -41.676 33.458 8.763 1.00 47.26 ? 361 ASP B CA 1 ATOM 5953 C C . ASP B 1 363 ? -41.609 34.024 7.318 1.00 50.25 ? 361 ASP B C 1 ATOM 5954 O O . ASP B 1 363 ? -41.593 35.241 7.162 1.00 48.05 ? 361 ASP B O 1 ATOM 5955 C CB . ASP B 1 363 ? -40.859 34.330 9.739 1.00 49.40 ? 361 ASP B CB 1 ATOM 5956 C CG . ASP B 1 363 ? -39.411 34.530 9.337 1.00 61.71 ? 361 ASP B CG 1 ATOM 5957 O OD1 . ASP B 1 363 ? -38.834 33.608 8.688 1.00 63.07 ? 361 ASP B OD1 1 ATOM 5958 O OD2 . ASP B 1 363 ? -38.877 35.637 9.589 1.00 67.30 ? 361 ASP B OD2 1 ATOM 5959 N N . CYS B 1 364 ? -41.592 33.142 6.276 1.00 49.28 ? 362 CYS B N 1 ATOM 5960 C CA . CYS B 1 364 ? -41.510 33.509 4.846 1.00 49.86 ? 362 CYS B CA 1 ATOM 5961 C C . CYS B 1 364 ? -42.881 33.615 4.123 1.00 56.26 ? 362 CYS B C 1 ATOM 5962 O O . CYS B 1 364 ? -42.978 34.354 3.142 1.00 55.96 ? 362 CYS B O 1 ATOM 5963 C CB . CYS B 1 364 ? -40.580 32.558 4.097 1.00 49.81 ? 362 CYS B CB 1 ATOM 5964 S SG . CYS B 1 364 ? -38.801 32.839 4.356 1.00 53.60 ? 362 CYS B SG 1 ATOM 5965 N N . ALA B 1 365 ? -43.915 32.859 4.578 1.00 53.75 ? 363 ALA B N 1 ATOM 5966 C CA . ALA B 1 365 ? -45.262 32.817 3.969 1.00 53.63 ? 363 ALA B CA 1 ATOM 5967 C C . ALA B 1 365 ? -46.054 34.145 3.975 1.00 57.70 ? 363 ALA B C 1 ATOM 5968 O O . ALA B 1 365 ? -46.947 34.333 3.144 1.00 56.95 ? 363 ALA B O 1 ATOM 5969 C CB . ALA B 1 365 ? -46.094 31.719 4.620 1.00 54.16 ? 363 ALA B CB 1 ATOM 5970 N N . ALA B 1 366 ? -45.751 35.031 4.922 1.00 54.29 ? 364 ALA B N 1 ATOM 5971 C CA . ALA B 1 366 ? -46.413 36.319 5.072 1.00 54.40 ? 364 ALA B CA 1 ATOM 5972 C C . ALA B 1 366 ? -46.244 37.179 3.818 1.00 58.03 ? 364 ALA B C 1 ATOM 5973 O O . ALA B 1 366 ? -47.236 37.638 3.234 1.00 59.20 ? 364 ALA B O 1 ATOM 5974 C CB . ALA B 1 366 ? -45.843 37.041 6.292 1.00 55.30 ? 364 ALA B CB 1 ATOM 5975 N N . HIS B 1 367 ? -44.984 37.334 3.385 1.00 52.38 ? 365 HIS B N 1 ATOM 5976 C CA . HIS B 1 367 ? -44.510 38.124 2.245 1.00 50.23 ? 365 HIS B CA 1 ATOM 5977 C C . HIS B 1 367 ? -45.108 37.748 0.879 1.00 55.63 ? 365 HIS B C 1 ATOM 5978 O O . HIS B 1 367 ? -45.559 36.614 0.681 1.00 53.78 ? 365 HIS B O 1 ATOM 5979 C CB . HIS B 1 367 ? -42.999 38.022 2.184 1.00 49.14 ? 365 HIS B CB 1 ATOM 5980 C CG . HIS B 1 367 ? -42.314 38.308 3.480 1.00 51.23 ? 365 HIS B CG 1 ATOM 5981 N ND1 . HIS B 1 367 ? -42.068 39.606 3.894 1.00 52.25 ? 365 HIS B ND1 1 ATOM 5982 C CD2 . HIS B 1 367 ? -41.789 37.453 4.388 1.00 52.43 ? 365 HIS B CD2 1 ATOM 5983 C CE1 . HIS B 1 367 ? -41.396 39.501 5.032 1.00 51.45 ? 365 HIS B CE1 1 ATOM 5984 N NE2 . HIS B 1 367 ? -41.207 38.227 5.375 1.00 51.77 ? 365 HIS B NE2 1 ATOM 5985 N N . SER B 1 368 ? -45.074 38.711 -0.073 1.00 54.87 ? 366 SER B N 1 ATOM 5986 C CA . SER B 1 368 ? -45.589 38.575 -1.447 1.00 55.63 ? 366 SER B CA 1 ATOM 5987 C C . SER B 1 368 ? -44.965 39.613 -2.396 1.00 61.88 ? 366 SER B C 1 ATOM 5988 O O . SER B 1 368 ? -44.801 40.776 -2.032 1.00 60.78 ? 366 SER B O 1 ATOM 5989 C CB . SER B 1 368 ? -47.117 38.674 -1.465 1.00 59.35 ? 366 SER B CB 1 ATOM 5990 O OG . SER B 1 368 ? -47.671 38.797 -2.765 1.00 69.64 ? 366 SER B OG 1 ATOM 5991 N N . LEU B 1 369 ? -44.639 39.182 -3.622 1.00 61.81 ? 367 LEU B N 1 ATOM 5992 C CA . LEU B 1 369 ? -44.041 40.034 -4.658 1.00 62.49 ? 367 LEU B CA 1 ATOM 5993 C C . LEU B 1 369 ? -45.046 41.030 -5.233 1.00 69.89 ? 367 LEU B C 1 ATOM 5994 O O . LEU B 1 369 ? -44.634 42.103 -5.696 1.00 70.06 ? 367 LEU B O 1 ATOM 5995 C CB . LEU B 1 369 ? -43.380 39.199 -5.768 1.00 61.76 ? 367 LEU B CB 1 ATOM 5996 C CG . LEU B 1 369 ? -42.139 38.401 -5.346 1.00 64.65 ? 367 LEU B CG 1 ATOM 5997 C CD1 . LEU B 1 369 ? -41.893 37.252 -6.283 1.00 64.77 ? 367 LEU B CD1 1 ATOM 5998 C CD2 . LEU B 1 369 ? -40.907 39.270 -5.260 1.00 62.29 ? 367 LEU B CD2 1 ATOM 5999 N N . ARG B 1 370 ? -46.367 40.692 -5.154 1.00 67.47 ? 368 ARG B N 1 ATOM 6000 C CA . ARG B 1 370 ? -47.489 41.534 -5.608 1.00 67.31 ? 368 ARG B CA 1 ATOM 6001 C C . ARG B 1 370 ? -47.640 42.762 -4.730 1.00 73.33 ? 368 ARG B C 1 ATOM 6002 O O . ARG B 1 370 ? -48.185 43.765 -5.182 1.00 73.75 ? 368 ARG B O 1 ATOM 6003 C CB . ARG B 1 370 ? -48.810 40.753 -5.579 1.00 64.18 ? 368 ARG B CB 1 ATOM 6004 C CG . ARG B 1 370 ? -49.055 39.923 -6.813 1.00 73.11 ? 368 ARG B CG 1 ATOM 6005 C CD . ARG B 1 370 ? -49.730 38.610 -6.469 1.00 82.17 ? 368 ARG B CD 1 ATOM 6006 N NE . ARG B 1 370 ? -50.251 37.939 -7.662 1.00 87.66 ? 368 ARG B NE 1 ATOM 6007 C CZ . ARG B 1 370 ? -50.620 36.662 -7.710 1.00 103.28 ? 368 ARG B CZ 1 ATOM 6008 N NH1 . ARG B 1 370 ? -50.508 35.888 -6.634 1.00 91.92 ? 368 ARG B NH1 1 ATOM 6009 N NH2 . ARG B 1 370 ? -51.091 36.145 -8.836 1.00 88.52 ? 368 ARG B NH2 1 ATOM 6010 N N . ALA B 1 371 ? -47.210 42.667 -3.466 1.00 71.23 ? 369 ALA B N 1 ATOM 6011 C CA . ALA B 1 371 ? -47.339 43.743 -2.488 1.00 71.81 ? 369 ALA B CA 1 ATOM 6012 C C . ALA B 1 371 ? -46.077 44.607 -2.369 1.00 76.83 ? 369 ALA B C 1 ATOM 6013 O O . ALA B 1 371 ? -45.953 45.399 -1.435 1.00 76.21 ? 369 ALA B O 1 ATOM 6014 C CB . ALA B 1 371 ? -47.734 43.161 -1.135 1.00 72.55 ? 369 ALA B CB 1 ATOM 6015 N N . VAL B 1 372 ? -45.142 44.463 -3.317 1.00 74.64 ? 370 VAL B N 1 ATOM 6016 C CA . VAL B 1 372 ? -43.893 45.242 -3.312 1.00 74.65 ? 370 VAL B CA 1 ATOM 6017 C C . VAL B 1 372 ? -43.704 45.959 -4.694 1.00 76.12 ? 370 VAL B C 1 ATOM 6018 O O . VAL B 1 372 ? -44.325 45.536 -5.680 1.00 74.98 ? 370 VAL B O 1 ATOM 6019 C CB . VAL B 1 372 ? -42.638 44.426 -2.822 1.00 79.13 ? 370 VAL B CB 1 ATOM 6020 C CG1 . VAL B 1 372 ? -42.824 43.909 -1.391 1.00 79.01 ? 370 VAL B CG1 1 ATOM 6021 C CG2 . VAL B 1 372 ? -42.274 43.280 -3.768 1.00 79.00 ? 370 VAL B CG2 1 ATOM 6022 N N . PRO B 1 373 ? -42.917 47.059 -4.786 1.00 71.53 ? 371 PRO B N 1 ATOM 6023 C CA . PRO B 1 373 ? -42.795 47.761 -6.084 1.00 71.19 ? 371 PRO B CA 1 ATOM 6024 C C . PRO B 1 373 ? -41.961 47.029 -7.134 1.00 73.22 ? 371 PRO B C 1 ATOM 6025 O O . PRO B 1 373 ? -40.747 46.876 -6.950 1.00 74.21 ? 371 PRO B O 1 ATOM 6026 C CB . PRO B 1 373 ? -42.197 49.119 -5.706 1.00 73.05 ? 371 PRO B CB 1 ATOM 6027 C CG . PRO B 1 373 ? -41.467 48.876 -4.434 1.00 77.27 ? 371 PRO B CG 1 ATOM 6028 C CD . PRO B 1 373 ? -42.133 47.730 -3.727 1.00 72.80 ? 371 PRO B CD 1 ATOM 6029 N N . PHE B 1 374 ? -42.604 46.573 -8.238 1.00 65.88 ? 372 PHE B N 1 ATOM 6030 C CA . PHE B 1 374 ? -41.875 45.851 -9.278 1.00 63.44 ? 372 PHE B CA 1 ATOM 6031 C C . PHE B 1 374 ? -41.117 46.770 -10.218 1.00 64.46 ? 372 PHE B C 1 ATOM 6032 O O . PHE B 1 374 ? -41.666 47.705 -10.805 1.00 62.78 ? 372 PHE B O 1 ATOM 6033 C CB . PHE B 1 374 ? -42.729 44.847 -10.061 1.00 64.46 ? 372 PHE B CB 1 ATOM 6034 C CG . PHE B 1 374 ? -41.912 44.000 -11.021 1.00 65.41 ? 372 PHE B CG 1 ATOM 6035 C CD1 . PHE B 1 374 ? -41.067 42.999 -10.551 1.00 67.51 ? 372 PHE B CD1 1 ATOM 6036 C CD2 . PHE B 1 374 ? -41.985 44.206 -12.395 1.00 66.41 ? 372 PHE B CD2 1 ATOM 6037 C CE1 . PHE B 1 374 ? -40.320 42.216 -11.441 1.00 67.64 ? 372 PHE B CE1 1 ATOM 6038 C CE2 . PHE B 1 374 ? -41.229 43.428 -13.279 1.00 67.99 ? 372 PHE B CE2 1 ATOM 6039 C CZ . PHE B 1 374 ? -40.409 42.436 -12.797 1.00 65.89 ? 372 PHE B CZ 1 ATOM 6040 N N . GLU B 1 375 ? -39.830 46.466 -10.354 1.00 59.60 ? 373 GLU B N 1 ATOM 6041 C CA . GLU B 1 375 ? -38.913 47.187 -11.203 1.00 58.17 ? 373 GLU B CA 1 ATOM 6042 C C . GLU B 1 375 ? -38.181 46.179 -12.083 1.00 56.50 ? 373 GLU B C 1 ATOM 6043 O O . GLU B 1 375 ? -37.269 45.479 -11.630 1.00 56.08 ? 373 GLU B O 1 ATOM 6044 C CB . GLU B 1 375 ? -37.989 48.085 -10.358 1.00 59.92 ? 373 GLU B CB 1 ATOM 6045 C CG . GLU B 1 375 ? -38.694 49.364 -9.902 1.00 77.14 ? 373 GLU B CG 1 ATOM 6046 C CD . GLU B 1 375 ? -38.340 49.933 -8.536 1.00 113.38 ? 373 GLU B CD 1 ATOM 6047 O OE1 . GLU B 1 375 ? -37.181 49.754 -8.088 1.00 115.49 ? 373 GLU B OE1 1 ATOM 6048 O OE2 . GLU B 1 375 ? -39.218 50.592 -7.928 1.00 106.16 ? 373 GLU B OE2 1 ATOM 6049 N N . GLN B 1 376 ? -38.626 46.082 -13.319 1.00 48.85 ? 374 GLN B N 1 ATOM 6050 C CA . GLN B 1 376 ? -38.058 45.191 -14.288 1.00 46.19 ? 374 GLN B CA 1 ATOM 6051 C C . GLN B 1 376 ? -36.672 45.603 -14.624 1.00 49.79 ? 374 GLN B C 1 ATOM 6052 O O . GLN B 1 376 ? -36.379 46.757 -14.705 1.00 50.03 ? 374 GLN B O 1 ATOM 6053 C CB . GLN B 1 376 ? -38.888 45.181 -15.543 1.00 45.95 ? 374 GLN B CB 1 ATOM 6054 C CG . GLN B 1 376 ? -38.531 44.066 -16.487 1.00 52.34 ? 374 GLN B CG 1 ATOM 6055 C CD . GLN B 1 376 ? -39.478 43.954 -17.640 1.00 65.35 ? 374 GLN B CD 1 ATOM 6056 O OE1 . GLN B 1 376 ? -39.082 43.926 -18.780 1.00 60.41 ? 374 GLN B OE1 1 ATOM 6057 N NE2 . GLN B 1 376 ? -40.736 43.888 -17.341 1.00 57.79 ? 374 GLN B NE2 1 ATOM 6058 N N . GLU B 1 377 ? -35.821 44.621 -14.821 1.00 45.07 ? 375 GLU B N 1 ATOM 6059 C CA . GLU B 1 377 ? -34.429 44.832 -15.176 1.00 44.50 ? 375 GLU B CA 1 ATOM 6060 C C . GLU B 1 377 ? -34.410 45.232 -16.667 1.00 46.49 ? 375 GLU B C 1 ATOM 6061 O O . GLU B 1 377 ? -35.200 44.718 -17.465 1.00 45.57 ? 375 GLU B O 1 ATOM 6062 C CB . GLU B 1 377 ? -33.614 43.553 -14.869 1.00 46.01 ? 375 GLU B CB 1 ATOM 6063 C CG . GLU B 1 377 ? -32.113 43.779 -14.747 1.00 55.90 ? 375 GLU B CG 1 ATOM 6064 C CD . GLU B 1 377 ? -31.394 43.957 -16.070 1.00 61.55 ? 375 GLU B CD 1 ATOM 6065 O OE1 . GLU B 1 377 ? -31.818 43.309 -17.050 1.00 57.74 ? 375 GLU B OE1 1 ATOM 6066 O OE2 . GLU B 1 377 ? -30.449 44.775 -16.144 1.00 49.35 ? 375 GLU B OE2 1 ATOM 6067 N N . SER B 1 378 ? -33.551 46.193 -17.011 1.00 42.29 ? 376 SER B N 1 ATOM 6068 C CA . SER B 1 378 ? -33.456 46.801 -18.333 1.00 41.56 ? 376 SER B CA 1 ATOM 6069 C C . SER B 1 378 ? -33.292 45.818 -19.478 1.00 44.56 ? 376 SER B C 1 ATOM 6070 O O . SER B 1 378 ? -33.959 45.974 -20.494 1.00 45.15 ? 376 SER B O 1 ATOM 6071 C CB . SER B 1 378 ? -32.351 47.858 -18.374 1.00 46.16 ? 376 SER B CB 1 ATOM 6072 O OG . SER B 1 378 ? -32.403 48.598 -19.587 1.00 57.21 ? 376 SER B OG 1 ATOM 6073 N N . LYS B 1 379 ? -32.431 44.813 -19.319 1.00 39.08 ? 377 LYS B N 1 ATOM 6074 C CA . LYS B 1 379 ? -32.126 43.853 -20.369 1.00 37.27 ? 377 LYS B CA 1 ATOM 6075 C C . LYS B 1 379 ? -33.074 42.635 -20.436 1.00 40.91 ? 377 LYS B C 1 ATOM 6076 O O . LYS B 1 379 ? -32.731 41.654 -21.099 1.00 42.78 ? 377 LYS B O 1 ATOM 6077 C CB . LYS B 1 379 ? -30.651 43.406 -20.252 1.00 37.95 ? 377 LYS B CB 1 ATOM 6078 C CG . LYS B 1 379 ? -29.670 44.557 -20.386 1.00 35.99 ? 377 LYS B CG 1 ATOM 6079 C CD . LYS B 1 379 ? -28.253 44.068 -20.665 1.00 48.48 ? 377 LYS B CD 1 ATOM 6080 C CE . LYS B 1 379 ? -27.253 45.167 -20.998 1.00 44.95 ? 377 LYS B CE 1 ATOM 6081 N NZ . LYS B 1 379 ? -26.781 45.882 -19.776 1.00 43.75 ? 377 LYS B NZ 1 ATOM 6082 N N . ILE B 1 380 ? -34.248 42.675 -19.802 1.00 35.98 ? 378 ILE B N 1 ATOM 6083 C CA . ILE B 1 380 ? -35.170 41.525 -19.856 1.00 37.09 ? 378 ILE B CA 1 ATOM 6084 C C . ILE B 1 380 ? -35.566 41.207 -21.303 1.00 44.65 ? 378 ILE B C 1 ATOM 6085 O O . ILE B 1 380 ? -35.622 40.040 -21.674 1.00 46.63 ? 378 ILE B O 1 ATOM 6086 C CB . ILE B 1 380 ? -36.400 41.695 -18.903 1.00 40.73 ? 378 ILE B CB 1 ATOM 6087 C CG1 . ILE B 1 380 ? -36.013 41.587 -17.409 1.00 41.38 ? 378 ILE B CG1 1 ATOM 6088 C CG2 . ILE B 1 380 ? -37.558 40.746 -19.250 1.00 41.42 ? 378 ILE B CG2 1 ATOM 6089 C CD1 . ILE B 1 380 ? -35.420 40.166 -16.883 1.00 48.38 ? 378 ILE B CD1 1 ATOM 6090 N N . MET B 1 381 ? -35.793 42.249 -22.124 1.00 42.92 ? 379 MET B N 1 ATOM 6091 C CA . MET B 1 381 ? -36.129 42.174 -23.561 1.00 43.00 ? 379 MET B CA 1 ATOM 6092 C C . MET B 1 381 ? -35.039 41.368 -24.276 1.00 42.16 ? 379 MET B C 1 ATOM 6093 O O . MET B 1 381 ? -35.328 40.441 -25.010 1.00 39.79 ? 379 MET B O 1 ATOM 6094 C CB . MET B 1 381 ? -36.235 43.612 -24.137 1.00 46.05 ? 379 MET B CB 1 ATOM 6095 C CG . MET B 1 381 ? -36.560 43.689 -25.613 1.00 50.34 ? 379 MET B CG 1 ATOM 6096 S SD . MET B 1 381 ? -36.019 45.272 -26.326 1.00 56.10 ? 379 MET B SD 1 ATOM 6097 C CE . MET B 1 381 ? -34.487 44.820 -26.967 1.00 53.39 ? 379 MET B CE 1 ATOM 6098 N N . PHE B 1 382 ? -33.785 41.685 -23.984 1.00 39.41 ? 380 PHE B N 1 ATOM 6099 C CA . PHE B 1 382 ? -32.640 40.964 -24.507 1.00 39.41 ? 380 PHE B CA 1 ATOM 6100 C C . PHE B 1 382 ? -32.637 39.488 -24.129 1.00 43.82 ? 380 PHE B C 1 ATOM 6101 O O . PHE B 1 382 ? -32.306 38.683 -24.967 1.00 46.98 ? 380 PHE B O 1 ATOM 6102 C CB . PHE B 1 382 ? -31.356 41.663 -24.106 1.00 41.21 ? 380 PHE B CB 1 ATOM 6103 C CG . PHE B 1 382 ? -31.255 43.032 -24.728 1.00 43.86 ? 380 PHE B CG 1 ATOM 6104 C CD1 . PHE B 1 382 ? -31.134 43.182 -26.113 1.00 46.74 ? 380 PHE B CD1 1 ATOM 6105 C CD2 . PHE B 1 382 ? -31.300 44.181 -23.937 1.00 47.15 ? 380 PHE B CD2 1 ATOM 6106 C CE1 . PHE B 1 382 ? -31.011 44.460 -26.687 1.00 48.15 ? 380 PHE B CE1 1 ATOM 6107 C CE2 . PHE B 1 382 ? -31.205 45.461 -24.516 1.00 49.69 ? 380 PHE B CE2 1 ATOM 6108 C CZ . PHE B 1 382 ? -31.062 45.590 -25.888 1.00 47.56 ? 380 PHE B CZ 1 ATOM 6109 N N . VAL B 1 383 ? -33.077 39.122 -22.926 1.00 38.78 ? 381 VAL B N 1 ATOM 6110 C CA . VAL B 1 383 ? -33.151 37.724 -22.502 1.00 38.05 ? 381 VAL B CA 1 ATOM 6111 C C . VAL B 1 383 ? -34.254 36.981 -23.257 1.00 42.72 ? 381 VAL B C 1 ATOM 6112 O O . VAL B 1 383 ? -33.983 35.886 -23.743 1.00 43.12 ? 381 VAL B O 1 ATOM 6113 C CB . VAL B 1 383 ? -33.232 37.529 -20.954 1.00 39.93 ? 381 VAL B CB 1 ATOM 6114 C CG1 . VAL B 1 383 ? -33.043 36.061 -20.579 1.00 38.63 ? 381 VAL B CG1 1 ATOM 6115 C CG2 . VAL B 1 383 ? -32.187 38.384 -20.243 1.00 38.97 ? 381 VAL B CG2 1 ATOM 6116 N N . VAL B 1 384 ? -35.461 37.585 -23.403 1.00 40.12 ? 382 VAL B N 1 ATOM 6117 C CA . VAL B 1 384 ? -36.602 37.011 -24.162 1.00 40.16 ? 382 VAL B CA 1 ATOM 6118 C C . VAL B 1 384 ? -36.249 36.883 -25.650 1.00 40.61 ? 382 VAL B C 1 ATOM 6119 O O . VAL B 1 384 ? -36.394 35.812 -26.258 1.00 40.74 ? 382 VAL B O 1 ATOM 6120 C CB . VAL B 1 384 ? -37.935 37.796 -23.927 1.00 44.54 ? 382 VAL B CB 1 ATOM 6121 C CG1 . VAL B 1 384 ? -39.063 37.308 -24.844 1.00 44.40 ? 382 VAL B CG1 1 ATOM 6122 C CG2 . VAL B 1 384 ? -38.363 37.703 -22.474 1.00 43.80 ? 382 VAL B CG2 1 ATOM 6123 N N . ASN B 1 385 ? -35.746 37.959 -26.218 1.00 36.33 ? 383 ASN B N 1 ATOM 6124 C CA . ASN B 1 385 ? -35.308 37.956 -27.611 1.00 37.13 ? 383 ASN B CA 1 ATOM 6125 C C . ASN B 1 385 ? -34.307 36.834 -27.888 1.00 41.46 ? 383 ASN B C 1 ATOM 6126 O O . ASN B 1 385 ? -34.478 36.103 -28.867 1.00 41.41 ? 383 ASN B O 1 ATOM 6127 C CB . ASN B 1 385 ? -34.736 39.327 -28.020 1.00 35.14 ? 383 ASN B CB 1 ATOM 6128 C CG . ASN B 1 385 ? -35.764 40.441 -28.021 1.00 59.18 ? 383 ASN B CG 1 ATOM 6129 O OD1 . ASN B 1 385 ? -36.998 40.237 -28.012 1.00 41.00 ? 383 ASN B OD1 1 ATOM 6130 N ND2 . ASN B 1 385 ? -35.271 41.666 -28.026 1.00 62.45 ? 383 ASN B ND2 1 ATOM 6131 N N . ALA B 1 386 ? -33.290 36.679 -27.014 1.00 38.19 ? 384 ALA B N 1 ATOM 6132 C CA . ALA B 1 386 ? -32.270 35.640 -27.162 1.00 38.60 ? 384 ALA B CA 1 ATOM 6133 C C . ALA B 1 386 ? -32.842 34.226 -27.098 1.00 42.58 ? 384 ALA B C 1 ATOM 6134 O O . ALA B 1 386 ? -32.364 33.347 -27.818 1.00 42.72 ? 384 ALA B O 1 ATOM 6135 C CB . ALA B 1 386 ? -31.149 35.831 -26.159 1.00 38.96 ? 384 ALA B CB 1 ATOM 6136 N N . VAL B 1 387 ? -33.903 34.025 -26.297 1.00 38.91 ? 385 VAL B N 1 ATOM 6137 C CA . VAL B 1 387 ? -34.539 32.706 -26.162 1.00 38.08 ? 385 VAL B CA 1 ATOM 6138 C C . VAL B 1 387 ? -35.337 32.420 -27.407 1.00 40.72 ? 385 VAL B C 1 ATOM 6139 O O . VAL B 1 387 ? -35.169 31.365 -28.022 1.00 39.05 ? 385 VAL B O 1 ATOM 6140 C CB . VAL B 1 387 ? -35.335 32.517 -24.851 1.00 40.97 ? 385 VAL B CB 1 ATOM 6141 C CG1 . VAL B 1 387 ? -35.928 31.120 -24.787 1.00 40.99 ? 385 VAL B CG1 1 ATOM 6142 C CG2 . VAL B 1 387 ? -34.447 32.764 -23.627 1.00 40.19 ? 385 VAL B CG2 1 ATOM 6143 N N . TYR B 1 388 ? -36.108 33.422 -27.846 1.00 37.84 ? 386 TYR B N 1 ATOM 6144 C CA . TYR B 1 388 ? -36.882 33.351 -29.073 1.00 36.16 ? 386 TYR B CA 1 ATOM 6145 C C . TYR B 1 388 ? -36.007 33.176 -30.289 1.00 39.42 ? 386 TYR B C 1 ATOM 6146 O O . TYR B 1 388 ? -36.370 32.391 -31.152 1.00 41.96 ? 386 TYR B O 1 ATOM 6147 C CB . TYR B 1 388 ? -37.778 34.559 -29.193 1.00 36.85 ? 386 TYR B CB 1 ATOM 6148 C CG . TYR B 1 388 ? -39.143 34.319 -28.588 1.00 39.70 ? 386 TYR B CG 1 ATOM 6149 C CD1 . TYR B 1 388 ? -39.373 34.519 -27.226 1.00 40.95 ? 386 TYR B CD1 1 ATOM 6150 C CD2 . TYR B 1 388 ? -40.215 33.910 -29.379 1.00 40.64 ? 386 TYR B CD2 1 ATOM 6151 C CE1 . TYR B 1 388 ? -40.636 34.317 -26.669 1.00 42.09 ? 386 TYR B CE1 1 ATOM 6152 C CE2 . TYR B 1 388 ? -41.478 33.696 -28.832 1.00 41.57 ? 386 TYR B CE2 1 ATOM 6153 C CZ . TYR B 1 388 ? -41.687 33.901 -27.478 1.00 50.81 ? 386 TYR B CZ 1 ATOM 6154 O OH . TYR B 1 388 ? -42.952 33.705 -26.963 1.00 52.06 ? 386 TYR B OH 1 ATOM 6155 N N . ALA B 1 389 ? -34.837 33.828 -30.345 1.00 34.31 ? 387 ALA B N 1 ATOM 6156 C CA . ALA B 1 389 ? -33.911 33.672 -31.471 1.00 34.87 ? 387 ALA B CA 1 ATOM 6157 C C . ALA B 1 389 ? -33.438 32.221 -31.623 1.00 42.39 ? 387 ALA B C 1 ATOM 6158 O O . ALA B 1 389 ? -33.389 31.706 -32.739 1.00 43.41 ? 387 ALA B O 1 ATOM 6159 C CB . ALA B 1 389 ? -32.722 34.598 -31.320 1.00 35.34 ? 387 ALA B CB 1 ATOM 6160 N N . MET B 1 390 ? -33.138 31.547 -30.513 1.00 39.56 ? 388 MET B N 1 ATOM 6161 C CA . MET B 1 390 ? -32.706 30.160 -30.562 1.00 38.77 ? 388 MET B CA 1 ATOM 6162 C C . MET B 1 390 ? -33.879 29.283 -30.983 1.00 42.87 ? 388 MET B C 1 ATOM 6163 O O . MET B 1 390 ? -33.668 28.302 -31.698 1.00 43.33 ? 388 MET B O 1 ATOM 6164 C CB . MET B 1 390 ? -32.115 29.720 -29.205 1.00 40.77 ? 388 MET B CB 1 ATOM 6165 C CG . MET B 1 390 ? -31.340 28.423 -29.273 1.00 44.07 ? 388 MET B CG 1 ATOM 6166 S SD . MET B 1 390 ? -29.755 28.582 -30.153 1.00 48.66 ? 388 MET B SD 1 ATOM 6167 C CE . MET B 1 390 ? -28.634 29.093 -28.804 1.00 44.88 ? 388 MET B CE 1 ATOM 6168 N N . ALA B 1 391 ? -35.117 29.652 -30.581 1.00 38.93 ? 389 ALA B N 1 ATOM 6169 C CA . ALA B 1 391 ? -36.330 28.879 -30.909 1.00 38.83 ? 389 ALA B CA 1 ATOM 6170 C C . ALA B 1 391 ? -36.701 29.001 -32.392 1.00 45.09 ? 389 ALA B C 1 ATOM 6171 O O . ALA B 1 391 ? -37.031 28.008 -33.039 1.00 45.14 ? 389 ALA B O 1 ATOM 6172 C CB . ALA B 1 391 ? -37.486 29.323 -30.033 1.00 39.44 ? 389 ALA B CB 1 ATOM 6173 N N . HIS B 1 392 ? -36.611 30.222 -32.932 1.00 43.13 ? 390 HIS B N 1 ATOM 6174 C CA . HIS B 1 392 ? -36.869 30.512 -34.330 1.00 42.92 ? 390 HIS B CA 1 ATOM 6175 C C . HIS B 1 392 ? -35.885 29.751 -35.219 1.00 48.42 ? 390 HIS B C 1 ATOM 6176 O O . HIS B 1 392 ? -36.313 29.098 -36.175 1.00 50.13 ? 390 HIS B O 1 ATOM 6177 C CB . HIS B 1 392 ? -36.850 32.021 -34.559 1.00 43.53 ? 390 HIS B CB 1 ATOM 6178 C CG . HIS B 1 392 ? -38.182 32.640 -34.307 1.00 46.89 ? 390 HIS B CG 1 ATOM 6179 N ND1 . HIS B 1 392 ? -39.127 32.742 -35.311 1.00 48.19 ? 390 HIS B ND1 1 ATOM 6180 C CD2 . HIS B 1 392 ? -38.714 33.115 -33.156 1.00 49.52 ? 390 HIS B CD2 1 ATOM 6181 C CE1 . HIS B 1 392 ? -40.189 33.295 -34.756 1.00 48.09 ? 390 HIS B CE1 1 ATOM 6182 N NE2 . HIS B 1 392 ? -39.992 33.547 -33.461 1.00 49.13 ? 390 HIS B NE2 1 ATOM 6183 N N . ALA B 1 393 ? -34.602 29.729 -34.828 1.00 43.74 ? 391 ALA B N 1 ATOM 6184 C CA . ALA B 1 393 ? -33.522 28.988 -35.500 1.00 43.75 ? 391 ALA B CA 1 ATOM 6185 C C . ALA B 1 393 ? -33.833 27.497 -35.592 1.00 47.88 ? 391 ALA B C 1 ATOM 6186 O O . ALA B 1 393 ? -33.649 26.906 -36.635 1.00 47.01 ? 391 ALA B O 1 ATOM 6187 C CB . ALA B 1 393 ? -32.185 29.204 -34.762 1.00 44.44 ? 391 ALA B CB 1 ATOM 6188 N N . LEU B 1 394 ? -34.338 26.900 -34.515 1.00 47.36 ? 392 LEU B N 1 ATOM 6189 C CA . LEU B 1 394 ? -34.665 25.474 -34.468 1.00 47.21 ? 392 LEU B CA 1 ATOM 6190 C C . LEU B 1 394 ? -35.883 25.150 -35.285 1.00 52.88 ? 392 LEU B C 1 ATOM 6191 O O . LEU B 1 394 ? -35.903 24.105 -35.924 1.00 53.33 ? 392 LEU B O 1 ATOM 6192 C CB . LEU B 1 394 ? -34.840 25.000 -33.019 1.00 46.61 ? 392 LEU B CB 1 ATOM 6193 C CG . LEU B 1 394 ? -33.573 24.978 -32.162 1.00 49.56 ? 392 LEU B CG 1 ATOM 6194 C CD1 . LEU B 1 394 ? -33.914 24.879 -30.694 1.00 49.47 ? 392 LEU B CD1 1 ATOM 6195 C CD2 . LEU B 1 394 ? -32.667 23.853 -32.570 1.00 51.41 ? 392 LEU B CD2 1 ATOM 6196 N N . HIS B 1 395 ? -36.897 26.038 -35.270 1.00 50.26 ? 393 HIS B N 1 ATOM 6197 C CA . HIS B 1 395 ? -38.138 25.882 -36.034 1.00 50.27 ? 393 HIS B CA 1 ATOM 6198 C C . HIS B 1 395 ? -37.757 25.873 -37.499 1.00 55.67 ? 393 HIS B C 1 ATOM 6199 O O . HIS B 1 395 ? -38.136 24.958 -38.229 1.00 57.65 ? 393 HIS B O 1 ATOM 6200 C CB . HIS B 1 395 ? -39.103 27.048 -35.759 1.00 51.01 ? 393 HIS B CB 1 ATOM 6201 C CG . HIS B 1 395 ? -40.445 26.887 -36.416 1.00 54.41 ? 393 HIS B CG 1 ATOM 6202 N ND1 . HIS B 1 395 ? -41.550 26.445 -35.706 1.00 56.03 ? 393 HIS B ND1 1 ATOM 6203 C CD2 . HIS B 1 395 ? -40.807 27.083 -37.703 1.00 56.13 ? 393 HIS B CD2 1 ATOM 6204 C CE1 . HIS B 1 395 ? -42.539 26.392 -36.576 1.00 55.41 ? 393 HIS B CE1 1 ATOM 6205 N NE2 . HIS B 1 395 ? -42.142 26.768 -37.791 1.00 55.81 ? 393 HIS B NE2 1 ATOM 6206 N N . ASN B 1 396 ? -36.960 26.879 -37.908 1.00 49.55 ? 394 ASN B N 1 ATOM 6207 C CA . ASN B 1 396 ? -36.441 27.041 -39.253 1.00 46.66 ? 394 ASN B CA 1 ATOM 6208 C C . ASN B 1 396 ? -35.594 25.841 -39.672 1.00 48.59 ? 394 ASN B C 1 ATOM 6209 O O . ASN B 1 396 ? -35.764 25.345 -40.790 1.00 49.09 ? 394 ASN B O 1 ATOM 6210 C CB . ASN B 1 396 ? -35.726 28.386 -39.368 1.00 39.21 ? 394 ASN B CB 1 ATOM 6211 C CG . ASN B 1 396 ? -36.699 29.553 -39.195 1.00 49.26 ? 394 ASN B CG 1 ATOM 6212 O OD1 . ASN B 1 396 ? -37.916 29.357 -39.127 1.00 51.21 ? 394 ASN B OD1 1 ATOM 6213 N ND2 . ASN B 1 396 ? -36.213 30.798 -39.113 1.00 28.80 ? 394 ASN B ND2 1 ATOM 6214 N N . MET B 1 397 ? -34.782 25.299 -38.746 1.00 43.52 ? 395 MET B N 1 ATOM 6215 C CA . MET B 1 397 ? -33.970 24.107 -39.012 1.00 43.45 ? 395 MET B CA 1 ATOM 6216 C C . MET B 1 397 ? -34.872 22.906 -39.189 1.00 48.90 ? 395 MET B C 1 ATOM 6217 O O . MET B 1 397 ? -34.628 22.110 -40.090 1.00 49.59 ? 395 MET B O 1 ATOM 6218 C CB . MET B 1 397 ? -32.920 23.864 -37.910 1.00 45.39 ? 395 MET B CB 1 ATOM 6219 C CG . MET B 1 397 ? -32.041 22.658 -38.151 1.00 48.73 ? 395 MET B CG 1 ATOM 6220 S SD . MET B 1 397 ? -30.549 22.799 -37.173 1.00 53.40 ? 395 MET B SD 1 ATOM 6221 C CE . MET B 1 397 ? -29.646 21.402 -37.696 1.00 49.71 ? 395 MET B CE 1 ATOM 6222 N N . HIS B 1 398 ? -35.936 22.810 -38.360 1.00 46.02 ? 396 HIS B N 1 ATOM 6223 C CA . HIS B 1 398 ? -36.918 21.734 -38.381 1.00 45.93 ? 396 HIS B CA 1 ATOM 6224 C C . HIS B 1 398 ? -37.769 21.726 -39.650 1.00 53.15 ? 396 HIS B C 1 ATOM 6225 O O . HIS B 1 398 ? -38.142 20.649 -40.145 1.00 54.68 ? 396 HIS B O 1 ATOM 6226 C CB . HIS B 1 398 ? -37.809 21.815 -37.160 1.00 46.00 ? 396 HIS B CB 1 ATOM 6227 C CG . HIS B 1 398 ? -38.833 20.733 -37.127 1.00 48.58 ? 396 HIS B CG 1 ATOM 6228 N ND1 . HIS B 1 398 ? -40.151 20.986 -37.443 1.00 49.37 ? 396 HIS B ND1 1 ATOM 6229 C CD2 . HIS B 1 398 ? -38.685 19.415 -36.858 1.00 49.48 ? 396 HIS B CD2 1 ATOM 6230 C CE1 . HIS B 1 398 ? -40.769 19.823 -37.327 1.00 48.50 ? 396 HIS B CE1 1 ATOM 6231 N NE2 . HIS B 1 398 ? -39.924 18.848 -36.984 1.00 48.90 ? 396 HIS B NE2 1 ATOM 6232 N N . ARG B 1 399 ? -38.075 22.920 -40.173 1.00 48.56 ? 397 ARG B N 1 ATOM 6233 C CA . ARG B 1 399 ? -38.861 23.094 -41.389 1.00 47.72 ? 397 ARG B CA 1 ATOM 6234 C C . ARG B 1 399 ? -38.061 22.519 -42.539 1.00 53.31 ? 397 ARG B C 1 ATOM 6235 O O . ARG B 1 399 ? -38.600 21.755 -43.348 1.00 53.93 ? 397 ARG B O 1 ATOM 6236 C CB . ARG B 1 399 ? -39.191 24.585 -41.594 1.00 44.07 ? 397 ARG B CB 1 ATOM 6237 C CG . ARG B 1 399 ? -39.836 24.910 -42.926 1.00 45.10 ? 397 ARG B CG 1 ATOM 6238 C CD . ARG B 1 399 ? -40.530 26.250 -42.841 1.00 55.83 ? 397 ARG B CD 1 ATOM 6239 N NE . ARG B 1 399 ? -39.621 27.392 -42.923 1.00 54.78 ? 397 ARG B NE 1 ATOM 6240 C CZ . ARG B 1 399 ? -39.700 28.460 -42.140 1.00 73.39 ? 397 ARG B CZ 1 ATOM 6241 N NH1 . ARG B 1 399 ? -40.613 28.519 -41.177 1.00 67.86 ? 397 ARG B NH1 1 ATOM 6242 N NH2 . ARG B 1 399 ? -38.862 29.475 -42.305 1.00 63.17 ? 397 ARG B NH2 1 ATOM 6243 N N . ALA B 1 400 ? -36.751 22.821 -42.553 1.00 50.02 ? 398 ALA B N 1 ATOM 6244 C CA . ALA B 1 400 ? -35.845 22.327 -43.568 1.00 50.37 ? 398 ALA B CA 1 ATOM 6245 C C . ALA B 1 400 ? -35.460 20.858 -43.403 1.00 56.97 ? 398 ALA B C 1 ATOM 6246 O O . ALA B 1 400 ? -35.308 20.180 -44.418 1.00 58.77 ? 398 ALA B O 1 ATOM 6247 C CB . ALA B 1 400 ? -34.594 23.179 -43.609 1.00 51.06 ? 398 ALA B CB 1 ATOM 6248 N N . LEU B 1 401 ? -35.243 20.366 -42.176 1.00 53.53 ? 399 LEU B N 1 ATOM 6249 C CA . LEU B 1 401 ? -34.751 18.989 -42.027 1.00 54.73 ? 399 LEU B CA 1 ATOM 6250 C C . LEU B 1 401 ? -35.837 17.942 -41.819 1.00 62.34 ? 399 LEU B C 1 ATOM 6251 O O . LEU B 1 401 ? -35.589 16.755 -42.033 1.00 60.96 ? 399 LEU B O 1 ATOM 6252 C CB . LEU B 1 401 ? -33.671 18.865 -40.916 1.00 54.41 ? 399 LEU B CB 1 ATOM 6253 C CG . LEU B 1 401 ? -32.335 19.631 -41.064 1.00 58.56 ? 399 LEU B CG 1 ATOM 6254 C CD1 . LEU B 1 401 ? -31.221 18.909 -40.364 1.00 57.24 ? 399 LEU B CD1 1 ATOM 6255 C CD2 . LEU B 1 401 ? -31.923 19.833 -42.525 1.00 62.87 ? 399 LEU B CD2 1 ATOM 6256 N N . CYS B 1 402 ? -37.016 18.362 -41.387 1.00 62.92 ? 400 CYS B N 1 ATOM 6257 C CA . CYS B 1 402 ? -38.083 17.424 -41.110 1.00 65.53 ? 400 CYS B CA 1 ATOM 6258 C C . CYS B 1 402 ? -39.308 17.894 -41.863 1.00 70.00 ? 400 CYS B C 1 ATOM 6259 O O . CYS B 1 402 ? -40.173 18.563 -41.282 1.00 69.16 ? 400 CYS B O 1 ATOM 6260 C CB . CYS B 1 402 ? -38.331 17.333 -39.608 1.00 67.78 ? 400 CYS B CB 1 ATOM 6261 S SG . CYS B 1 402 ? -36.836 17.043 -38.617 1.00 72.76 ? 400 CYS B SG 1 ATOM 6262 N N . PRO B 1 403 ? -39.361 17.601 -43.189 1.00 67.19 ? 401 PRO B N 1 ATOM 6263 C CA . PRO B 1 403 ? -40.476 18.117 -44.008 1.00 67.18 ? 401 PRO B CA 1 ATOM 6264 C C . PRO B 1 403 ? -41.857 17.510 -43.740 1.00 72.15 ? 401 PRO B C 1 ATOM 6265 O O . PRO B 1 403 ? -42.853 18.245 -43.703 1.00 70.80 ? 401 PRO B O 1 ATOM 6266 C CB . PRO B 1 403 ? -40.013 17.856 -45.446 1.00 68.53 ? 401 PRO B CB 1 ATOM 6267 C CG . PRO B 1 403 ? -39.028 16.758 -45.347 1.00 72.32 ? 401 PRO B CG 1 ATOM 6268 C CD . PRO B 1 403 ? -38.381 16.852 -44.012 1.00 67.88 ? 401 PRO B CD 1 ATOM 6269 N N . ASN B 1 404 ? -41.919 16.181 -43.580 1.00 70.62 ? 402 ASN B N 1 ATOM 6270 C CA . ASN B 1 404 ? -43.179 15.460 -43.402 1.00 71.75 ? 402 ASN B CA 1 ATOM 6271 C C . ASN B 1 404 ? -43.800 15.675 -41.996 1.00 76.67 ? 402 ASN B C 1 ATOM 6272 O O . ASN B 1 404 ? -44.850 16.325 -41.891 1.00 76.61 ? 402 ASN B O 1 ATOM 6273 C CB . ASN B 1 404 ? -43.006 13.960 -43.763 1.00 74.71 ? 402 ASN B CB 1 ATOM 6274 C CG . ASN B 1 404 ? -42.456 13.690 -45.168 1.00 98.54 ? 402 ASN B CG 1 ATOM 6275 O OD1 . ASN B 1 404 ? -42.914 14.244 -46.180 1.00 89.96 ? 402 ASN B OD1 1 ATOM 6276 N ND2 . ASN B 1 404 ? -41.470 12.805 -45.265 1.00 90.85 ? 402 ASN B ND2 1 ATOM 6277 N N . THR B 1 405 ? -43.112 15.186 -40.929 1.00 72.41 ? 403 THR B N 1 ATOM 6278 C CA . THR B 1 405 ? -43.517 15.245 -39.512 1.00 71.09 ? 403 THR B CA 1 ATOM 6279 C C . THR B 1 405 ? -43.385 16.634 -38.850 1.00 74.13 ? 403 THR B C 1 ATOM 6280 O O . THR B 1 405 ? -42.517 17.431 -39.220 1.00 73.56 ? 403 THR B O 1 ATOM 6281 C CB . THR B 1 405 ? -42.766 14.170 -38.693 1.00 74.38 ? 403 THR B CB 1 ATOM 6282 O OG1 . THR B 1 405 ? -43.263 14.174 -37.360 1.00 72.76 ? 403 THR B OG1 1 ATOM 6283 C CG2 . THR B 1 405 ? -41.239 14.343 -38.703 1.00 71.02 ? 403 THR B CG2 1 ATOM 6284 N N . THR B 1 406 ? -44.253 16.888 -37.837 1.00 70.10 ? 404 THR B N 1 ATOM 6285 C CA . THR B 1 406 ? -44.277 18.114 -37.012 1.00 69.06 ? 404 THR B CA 1 ATOM 6286 C C . THR B 1 406 ? -43.365 17.888 -35.794 1.00 68.85 ? 404 THR B C 1 ATOM 6287 O O . THR B 1 406 ? -43.079 18.818 -35.038 1.00 68.98 ? 404 THR B O 1 ATOM 6288 C CB . THR B 1 406 ? -45.715 18.433 -36.528 1.00 81.29 ? 404 THR B CB 1 ATOM 6289 O OG1 . THR B 1 406 ? -46.172 17.385 -35.667 1.00 84.79 ? 404 THR B OG1 1 ATOM 6290 C CG2 . THR B 1 406 ? -46.701 18.637 -37.671 1.00 81.52 ? 404 THR B CG2 1 ATOM 6291 N N . ARG B 1 407 ? -42.928 16.621 -35.639 1.00 61.71 ? 405 ARG B N 1 ATOM 6292 C CA . ARG B 1 407 ? -42.106 16.156 -34.541 1.00 61.01 ? 405 ARG B CA 1 ATOM 6293 C C . ARG B 1 407 ? -40.620 16.095 -34.905 1.00 65.47 ? 405 ARG B C 1 ATOM 6294 O O . ARG B 1 407 ? -40.258 16.238 -36.078 1.00 65.00 ? 405 ARG B O 1 ATOM 6295 C CB . ARG B 1 407 ? -42.635 14.790 -34.040 1.00 60.81 ? 405 ARG B CB 1 ATOM 6296 C CG . ARG B 1 407 ? -44.074 14.814 -33.455 1.00 68.60 ? 405 ARG B CG 1 ATOM 6297 C CD . ARG B 1 407 ? -44.119 15.200 -31.983 1.00 82.27 ? 405 ARG B CD 1 ATOM 6298 N NE . ARG B 1 407 ? -45.480 15.192 -31.448 1.00 100.91 ? 405 ARG B NE 1 ATOM 6299 C CZ . ARG B 1 407 ? -45.830 15.704 -30.270 1.00 124.61 ? 405 ARG B CZ 1 ATOM 6300 N NH1 . ARG B 1 407 ? -44.918 16.262 -29.479 1.00 111.19 ? 405 ARG B NH1 1 ATOM 6301 N NH2 . ARG B 1 407 ? -47.095 15.653 -29.869 1.00 118.06 ? 405 ARG B NH2 1 ATOM 6302 N N . LEU B 1 408 ? -39.775 15.877 -33.904 1.00 62.14 ? 406 LEU B N 1 ATOM 6303 C CA . LEU B 1 408 ? -38.356 15.816 -34.111 1.00 61.25 ? 406 LEU B CA 1 ATOM 6304 C C . LEU B 1 408 ? -37.987 14.573 -34.870 1.00 67.64 ? 406 LEU B C 1 ATOM 6305 O O . LEU B 1 408 ? -38.149 13.478 -34.379 1.00 67.01 ? 406 LEU B O 1 ATOM 6306 C CB . LEU B 1 408 ? -37.649 15.863 -32.768 1.00 60.63 ? 406 LEU B CB 1 ATOM 6307 C CG . LEU B 1 408 ? -36.176 16.205 -32.706 1.00 63.76 ? 406 LEU B CG 1 ATOM 6308 C CD1 . LEU B 1 408 ? -35.945 17.511 -33.402 1.00 63.71 ? 406 LEU B CD1 1 ATOM 6309 C CD2 . LEU B 1 408 ? -35.780 16.331 -31.271 1.00 66.23 ? 406 LEU B CD2 1 ATOM 6310 N N . CYS B 1 409 ? -37.476 14.770 -36.076 1.00 67.29 ? 407 CYS B N 1 ATOM 6311 C CA . CYS B 1 409 ? -37.097 13.681 -36.988 1.00 68.34 ? 407 CYS B CA 1 ATOM 6312 C C . CYS B 1 409 ? -35.625 13.271 -36.802 1.00 72.29 ? 407 CYS B C 1 ATOM 6313 O O . CYS B 1 409 ? -34.908 13.951 -36.063 1.00 72.27 ? 407 CYS B O 1 ATOM 6314 C CB . CYS B 1 409 ? -37.434 14.019 -38.441 1.00 69.24 ? 407 CYS B CB 1 ATOM 6315 S SG . CYS B 1 409 ? -36.289 15.181 -39.241 1.00 73.37 ? 407 CYS B SG 1 ATOM 6316 N N . ASP B 1 410 ? -35.186 12.155 -37.441 1.00 69.10 ? 408 ASP B N 1 ATOM 6317 C CA . ASP B 1 410 ? -33.829 11.593 -37.299 1.00 69.32 ? 408 ASP B CA 1 ATOM 6318 C C . ASP B 1 410 ? -32.696 12.515 -37.782 1.00 73.76 ? 408 ASP B C 1 ATOM 6319 O O . ASP B 1 410 ? -31.542 12.342 -37.368 1.00 73.70 ? 408 ASP B O 1 ATOM 6320 C CB . ASP B 1 410 ? -33.729 10.214 -37.970 1.00 71.33 ? 408 ASP B CB 1 ATOM 6321 C CG . ASP B 1 410 ? -34.648 9.145 -37.392 1.00 82.32 ? 408 ASP B CG 1 ATOM 6322 O OD1 . ASP B 1 410 ? -35.479 9.480 -36.506 1.00 81.54 ? 408 ASP B OD1 1 ATOM 6323 O OD2 . ASP B 1 410 ? -34.549 7.979 -37.834 1.00 89.89 ? 408 ASP B OD2 1 ATOM 6324 N N . ALA B 1 411 ? -33.026 13.487 -38.650 1.00 70.26 ? 409 ALA B N 1 ATOM 6325 C CA . ALA B 1 411 ? -32.079 14.479 -39.164 1.00 69.23 ? 409 ALA B CA 1 ATOM 6326 C C . ALA B 1 411 ? -31.600 15.370 -38.008 1.00 69.98 ? 409 ALA B C 1 ATOM 6327 O O . ALA B 1 411 ? -30.402 15.663 -37.913 1.00 71.01 ? 409 ALA B O 1 ATOM 6328 C CB . ALA B 1 411 ? -32.737 15.324 -40.251 1.00 69.66 ? 409 ALA B CB 1 ATOM 6329 N N . MET B 1 412 ? -32.523 15.742 -37.102 1.00 61.82 ? 410 MET B N 1 ATOM 6330 C CA . MET B 1 412 ? -32.217 16.588 -35.953 1.00 59.92 ? 410 MET B CA 1 ATOM 6331 C C . MET B 1 412 ? -31.855 15.783 -34.666 1.00 64.04 ? 410 MET B C 1 ATOM 6332 O O . MET B 1 412 ? -31.786 16.350 -33.573 1.00 63.09 ? 410 MET B O 1 ATOM 6333 C CB . MET B 1 412 ? -33.349 17.585 -35.729 1.00 61.37 ? 410 MET B CB 1 ATOM 6334 C CG . MET B 1 412 ? -33.250 18.792 -36.624 1.00 64.14 ? 410 MET B CG 1 ATOM 6335 S SD . MET B 1 412 ? -34.675 19.884 -36.466 1.00 67.68 ? 410 MET B SD 1 ATOM 6336 C CE . MET B 1 412 ? -34.258 20.755 -34.984 1.00 64.19 ? 410 MET B CE 1 ATOM 6337 N N . ARG B 1 413 ? -31.546 14.480 -34.830 1.00 60.87 ? 411 ARG B N 1 ATOM 6338 C CA . ARG B 1 413 ? -31.144 13.564 -33.760 1.00 60.05 ? 411 ARG B CA 1 ATOM 6339 C C . ARG B 1 413 ? -29.722 13.007 -34.058 1.00 63.28 ? 411 ARG B C 1 ATOM 6340 O O . ARG B 1 413 ? -29.605 11.955 -34.709 1.00 63.64 ? 411 ARG B O 1 ATOM 6341 C CB . ARG B 1 413 ? -32.157 12.412 -33.629 1.00 59.32 ? 411 ARG B CB 1 ATOM 6342 C CG . ARG B 1 413 ? -33.540 12.812 -33.140 1.00 69.78 ? 411 ARG B CG 1 ATOM 6343 C CD . ARG B 1 413 ? -34.310 11.588 -32.677 1.00 80.18 ? 411 ARG B CD 1 ATOM 6344 N NE . ARG B 1 413 ? -35.761 11.775 -32.715 1.00 91.16 ? 411 ARG B NE 1 ATOM 6345 C CZ . ARG B 1 413 ? -36.478 12.306 -31.728 1.00 104.11 ? 411 ARG B CZ 1 ATOM 6346 N NH1 . ARG B 1 413 ? -35.883 12.741 -30.622 1.00 87.75 ? 411 ARG B NH1 1 ATOM 6347 N NH2 . ARG B 1 413 ? -37.795 12.418 -31.843 1.00 90.06 ? 411 ARG B NH2 1 ATOM 6348 N N . PRO B 1 414 ? -28.628 13.703 -33.642 1.00 57.40 ? 412 PRO B N 1 ATOM 6349 C CA . PRO B 1 414 ? -28.585 14.987 -32.916 1.00 55.83 ? 412 PRO B CA 1 ATOM 6350 C C . PRO B 1 414 ? -28.524 16.171 -33.867 1.00 55.37 ? 412 PRO B C 1 ATOM 6351 O O . PRO B 1 414 ? -28.198 15.998 -35.040 1.00 58.05 ? 412 PRO B O 1 ATOM 6352 C CB . PRO B 1 414 ? -27.283 14.879 -32.110 1.00 57.38 ? 412 PRO B CB 1 ATOM 6353 C CG . PRO B 1 414 ? -26.377 13.995 -32.949 1.00 62.75 ? 412 PRO B CG 1 ATOM 6354 C CD . PRO B 1 414 ? -27.261 13.215 -33.923 1.00 58.51 ? 412 PRO B CD 1 ATOM 6355 N N . VAL B 1 415 ? -28.823 17.366 -33.360 1.00 44.88 ? 413 VAL B N 1 ATOM 6356 C CA . VAL B 1 415 ? -28.736 18.609 -34.120 1.00 41.81 ? 413 VAL B CA 1 ATOM 6357 C C . VAL B 1 415 ? -27.256 18.902 -34.427 1.00 45.67 ? 413 VAL B C 1 ATOM 6358 O O . VAL B 1 415 ? -26.414 18.751 -33.542 1.00 47.52 ? 413 VAL B O 1 ATOM 6359 C CB . VAL B 1 415 ? -29.379 19.781 -33.338 1.00 42.10 ? 413 VAL B CB 1 ATOM 6360 C CG1 . VAL B 1 415 ? -29.014 21.130 -33.955 1.00 41.15 ? 413 VAL B CG1 1 ATOM 6361 C CG2 . VAL B 1 415 ? -30.888 19.608 -33.234 1.00 41.04 ? 413 VAL B CG2 1 ATOM 6362 N N . ASN B 1 416 ? -26.945 19.288 -35.669 1.00 38.97 ? 414 ASN B N 1 ATOM 6363 C CA . ASN B 1 416 ? -25.601 19.684 -36.054 1.00 38.10 ? 414 ASN B CA 1 ATOM 6364 C C . ASN B 1 416 ? -25.481 21.190 -35.674 1.00 41.87 ? 414 ASN B C 1 ATOM 6365 O O . ASN B 1 416 ? -26.196 22.037 -36.230 1.00 41.91 ? 414 ASN B O 1 ATOM 6366 C CB . ASN B 1 416 ? -25.371 19.470 -37.563 1.00 37.19 ? 414 ASN B CB 1 ATOM 6367 C CG . ASN B 1 416 ? -23.982 19.822 -38.048 1.00 67.18 ? 414 ASN B CG 1 ATOM 6368 O OD1 . ASN B 1 416 ? -23.531 20.974 -37.998 1.00 69.55 ? 414 ASN B OD1 1 ATOM 6369 N ND2 . ASN B 1 416 ? -23.281 18.838 -38.559 1.00 58.79 ? 414 ASN B ND2 1 ATOM 6370 N N . GLY B 1 417 ? -24.601 21.487 -34.718 1.00 36.39 ? 415 GLY B N 1 ATOM 6371 C CA . GLY B 1 417 ? -24.384 22.842 -34.220 1.00 35.47 ? 415 GLY B CA 1 ATOM 6372 C C . GLY B 1 417 ? -23.893 23.820 -35.259 1.00 39.82 ? 415 GLY B C 1 ATOM 6373 O O . GLY B 1 417 ? -24.442 24.932 -35.370 1.00 37.42 ? 415 GLY B O 1 ATOM 6374 N N . ARG B 1 418 ? -22.886 23.388 -36.069 1.00 38.11 ? 416 ARG B N 1 ATOM 6375 C CA . ARG B 1 418 ? -22.314 24.233 -37.128 1.00 38.95 ? 416 ARG B CA 1 ATOM 6376 C C . ARG B 1 418 ? -23.384 24.753 -38.038 1.00 44.50 ? 416 ARG B C 1 ATOM 6377 O O . ARG B 1 418 ? -23.505 25.969 -38.223 1.00 45.25 ? 416 ARG B O 1 ATOM 6378 C CB . ARG B 1 418 ? -21.215 23.511 -37.924 1.00 41.05 ? 416 ARG B CB 1 ATOM 6379 C CG . ARG B 1 418 ? -20.471 24.395 -38.913 1.00 59.46 ? 416 ARG B CG 1 ATOM 6380 C CD . ARG B 1 418 ? -19.228 23.702 -39.442 1.00 79.33 ? 416 ARG B CD 1 ATOM 6381 N NE . ARG B 1 418 ? -19.044 23.916 -40.881 1.00 90.24 ? 416 ARG B NE 1 ATOM 6382 C CZ . ARG B 1 418 ? -18.176 24.771 -41.416 1.00 106.21 ? 416 ARG B CZ 1 ATOM 6383 N NH1 . ARG B 1 418 ? -18.082 24.892 -42.734 1.00 98.23 ? 416 ARG B NH1 1 ATOM 6384 N NH2 . ARG B 1 418 ? -17.393 25.509 -40.637 1.00 89.37 ? 416 ARG B NH2 1 ATOM 6385 N N . ARG B 1 419 ? -24.186 23.829 -38.569 1.00 42.20 ? 417 ARG B N 1 ATOM 6386 C CA . ARG B 1 419 ? -25.303 24.083 -39.477 1.00 42.03 ? 417 ARG B CA 1 ATOM 6387 C C . ARG B 1 419 ? -26.324 24.978 -38.803 1.00 47.08 ? 417 ARG B C 1 ATOM 6388 O O . ARG B 1 419 ? -26.762 25.974 -39.398 1.00 48.16 ? 417 ARG B O 1 ATOM 6389 C CB . ARG B 1 419 ? -25.937 22.742 -39.845 1.00 42.68 ? 417 ARG B CB 1 ATOM 6390 C CG . ARG B 1 419 ? -26.242 22.613 -41.317 1.00 45.93 ? 417 ARG B CG 1 ATOM 6391 C CD . ARG B 1 419 ? -27.101 21.404 -41.545 1.00 49.50 ? 417 ARG B CD 1 ATOM 6392 N NE . ARG B 1 419 ? -27.926 21.580 -42.735 1.00 61.09 ? 417 ARG B NE 1 ATOM 6393 C CZ . ARG B 1 419 ? -28.544 20.592 -43.364 1.00 66.04 ? 417 ARG B CZ 1 ATOM 6394 N NH1 . ARG B 1 419 ? -28.444 19.348 -42.920 1.00 59.93 ? 417 ARG B NH1 1 ATOM 6395 N NH2 . ARG B 1 419 ? -29.274 20.839 -44.435 1.00 47.55 ? 417 ARG B NH2 1 ATOM 6396 N N . LEU B 1 420 ? -26.667 24.643 -37.534 1.00 43.40 ? 418 LEU B N 1 ATOM 6397 C CA . LEU B 1 420 ? -27.616 25.395 -36.728 1.00 42.82 ? 418 LEU B CA 1 ATOM 6398 C C . LEU B 1 420 ? -27.197 26.884 -36.610 1.00 47.52 ? 418 LEU B C 1 ATOM 6399 O O . LEU B 1 420 ? -27.984 27.776 -36.969 1.00 47.54 ? 418 LEU B O 1 ATOM 6400 C CB . LEU B 1 420 ? -27.853 24.737 -35.341 1.00 41.90 ? 418 LEU B CB 1 ATOM 6401 C CG . LEU B 1 420 ? -28.665 25.565 -34.296 1.00 45.19 ? 418 LEU B CG 1 ATOM 6402 C CD1 . LEU B 1 420 ? -30.068 25.909 -34.799 1.00 44.61 ? 418 LEU B CD1 1 ATOM 6403 C CD2 . LEU B 1 420 ? -28.799 24.819 -33.004 1.00 46.69 ? 418 LEU B CD2 1 ATOM 6404 N N . TYR B 1 421 ? -25.951 27.129 -36.156 1.00 41.42 ? 419 TYR B N 1 ATOM 6405 C CA . TYR B 1 421 ? -25.426 28.472 -35.952 1.00 39.46 ? 419 TYR B CA 1 ATOM 6406 C C . TYR B 1 421 ? -25.294 29.274 -37.248 1.00 43.46 ? 419 TYR B C 1 ATOM 6407 O O . TYR B 1 421 ? -25.834 30.386 -37.334 1.00 41.29 ? 419 TYR B O 1 ATOM 6408 C CB . TYR B 1 421 ? -24.100 28.438 -35.158 1.00 39.10 ? 419 TYR B CB 1 ATOM 6409 C CG . TYR B 1 421 ? -23.462 29.805 -35.063 1.00 39.34 ? 419 TYR B CG 1 ATOM 6410 C CD1 . TYR B 1 421 ? -23.971 30.773 -34.208 1.00 40.91 ? 419 TYR B CD1 1 ATOM 6411 C CD2 . TYR B 1 421 ? -22.410 30.167 -35.903 1.00 39.54 ? 419 TYR B CD2 1 ATOM 6412 C CE1 . TYR B 1 421 ? -23.437 32.058 -34.174 1.00 43.08 ? 419 TYR B CE1 1 ATOM 6413 C CE2 . TYR B 1 421 ? -21.869 31.452 -35.876 1.00 39.09 ? 419 TYR B CE2 1 ATOM 6414 C CZ . TYR B 1 421 ? -22.372 32.385 -34.996 1.00 45.96 ? 419 TYR B CZ 1 ATOM 6415 O OH . TYR B 1 421 ? -21.834 33.641 -34.965 1.00 49.78 ? 419 TYR B OH 1 ATOM 6416 N N . LYS B 1 422 ? -24.549 28.719 -38.231 1.00 42.67 ? 420 LYS B N 1 ATOM 6417 C CA . LYS B 1 422 ? -24.224 29.353 -39.514 1.00 43.26 ? 420 LYS B CA 1 ATOM 6418 C C . LYS B 1 422 ? -25.414 29.582 -40.424 1.00 46.43 ? 420 LYS B C 1 ATOM 6419 O O . LYS B 1 422 ? -25.603 30.695 -40.920 1.00 46.33 ? 420 LYS B O 1 ATOM 6420 C CB . LYS B 1 422 ? -23.129 28.562 -40.257 1.00 46.04 ? 420 LYS B CB 1 ATOM 6421 C CG . LYS B 1 422 ? -21.705 29.060 -39.941 1.00 60.50 ? 420 LYS B CG 1 ATOM 6422 C CD . LYS B 1 422 ? -20.622 28.052 -40.372 1.00 71.14 ? 420 LYS B CD 1 ATOM 6423 C CE . LYS B 1 422 ? -19.243 28.405 -39.866 1.00 81.34 ? 420 LYS B CE 1 ATOM 6424 N NZ . LYS B 1 422 ? -18.259 28.508 -40.977 1.00 90.22 ? 420 LYS B NZ 1 ATOM 6425 N N . ASP B 1 423 ? -26.236 28.562 -40.611 1.00 42.00 ? 421 ASP B N 1 ATOM 6426 C CA . ASP B 1 423 ? -27.339 28.683 -41.540 1.00 42.13 ? 421 ASP B CA 1 ATOM 6427 C C . ASP B 1 423 ? -28.665 29.041 -40.920 1.00 45.25 ? 421 ASP B C 1 ATOM 6428 O O . ASP B 1 423 ? -29.525 29.527 -41.661 1.00 44.35 ? 421 ASP B O 1 ATOM 6429 C CB . ASP B 1 423 ? -27.458 27.410 -42.388 1.00 43.86 ? 421 ASP B CB 1 ATOM 6430 C CG . ASP B 1 423 ? -26.132 27.019 -43.021 1.00 45.48 ? 421 ASP B CG 1 ATOM 6431 O OD1 . ASP B 1 423 ? -25.312 27.948 -43.320 1.00 42.53 ? 421 ASP B OD1 1 ATOM 6432 O OD2 . ASP B 1 423 ? -25.889 25.792 -43.186 1.00 47.51 ? 421 ASP B OD2 1 ATOM 6433 N N . PHE B 1 424 ? -28.850 28.842 -39.591 1.00 40.67 ? 422 PHE B N 1 ATOM 6434 C CA . PHE B 1 424 ? -30.156 29.189 -39.001 1.00 39.05 ? 422 PHE B CA 1 ATOM 6435 C C . PHE B 1 424 ? -30.080 30.331 -37.997 1.00 42.33 ? 422 PHE B C 1 ATOM 6436 O O . PHE B 1 424 ? -30.777 31.319 -38.237 1.00 42.93 ? 422 PHE B O 1 ATOM 6437 C CB . PHE B 1 424 ? -30.915 27.964 -38.438 1.00 39.25 ? 422 PHE B CB 1 ATOM 6438 C CG . PHE B 1 424 ? -31.169 26.963 -39.539 1.00 39.56 ? 422 PHE B CG 1 ATOM 6439 C CD1 . PHE B 1 424 ? -30.227 25.977 -39.836 1.00 41.15 ? 422 PHE B CD1 1 ATOM 6440 C CD2 . PHE B 1 424 ? -32.277 27.091 -40.375 1.00 40.49 ? 422 PHE B CD2 1 ATOM 6441 C CE1 . PHE B 1 424 ? -30.429 25.091 -40.893 1.00 41.16 ? 422 PHE B CE1 1 ATOM 6442 C CE2 . PHE B 1 424 ? -32.497 26.185 -41.412 1.00 42.05 ? 422 PHE B CE2 1 ATOM 6443 C CZ . PHE B 1 424 ? -31.567 25.196 -41.669 1.00 40.32 ? 422 PHE B CZ 1 ATOM 6444 N N . VAL B 1 425 ? -29.257 30.239 -36.908 1.00 37.41 ? 423 VAL B N 1 ATOM 6445 C CA . VAL B 1 425 ? -29.146 31.322 -35.885 1.00 36.34 ? 423 VAL B CA 1 ATOM 6446 C C . VAL B 1 425 ? -28.944 32.701 -36.576 1.00 39.92 ? 423 VAL B C 1 ATOM 6447 O O . VAL B 1 425 ? -29.787 33.588 -36.488 1.00 38.48 ? 423 VAL B O 1 ATOM 6448 C CB . VAL B 1 425 ? -28.045 31.073 -34.799 1.00 38.79 ? 423 VAL B CB 1 ATOM 6449 C CG1 . VAL B 1 425 ? -27.884 32.300 -33.893 1.00 38.51 ? 423 VAL B CG1 1 ATOM 6450 C CG2 . VAL B 1 425 ? -28.326 29.822 -33.969 1.00 38.40 ? 423 VAL B CG2 1 ATOM 6451 N N . LEU B 1 426 ? -27.849 32.821 -37.319 1.00 37.35 ? 424 LEU B N 1 ATOM 6452 C CA . LEU B 1 426 ? -27.481 34.026 -38.035 1.00 37.38 ? 424 LEU B CA 1 ATOM 6453 C C . LEU B 1 426 ? -28.511 34.503 -39.092 1.00 43.39 ? 424 LEU B C 1 ATOM 6454 O O . LEU B 1 426 ? -28.441 35.655 -39.514 1.00 43.69 ? 424 LEU B O 1 ATOM 6455 C CB . LEU B 1 426 ? -26.094 33.822 -38.689 1.00 36.25 ? 424 LEU B CB 1 ATOM 6456 C CG . LEU B 1 426 ? -24.876 33.642 -37.761 1.00 36.91 ? 424 LEU B CG 1 ATOM 6457 C CD1 . LEU B 1 426 ? -23.593 33.694 -38.566 1.00 34.15 ? 424 LEU B CD1 1 ATOM 6458 C CD2 . LEU B 1 426 ? -24.845 34.698 -36.652 1.00 37.11 ? 424 LEU B CD2 1 ATOM 6459 N N . ASN B 1 427 ? -29.455 33.642 -39.503 1.00 39.75 ? 425 ASN B N 1 ATOM 6460 C CA . ASN B 1 427 ? -30.395 33.996 -40.562 1.00 39.45 ? 425 ASN B CA 1 ATOM 6461 C C . ASN B 1 427 ? -31.818 34.171 -40.107 1.00 46.45 ? 425 ASN B C 1 ATOM 6462 O O . ASN B 1 427 ? -32.716 34.226 -40.958 1.00 45.42 ? 425 ASN B O 1 ATOM 6463 C CB . ASN B 1 427 ? -30.314 33.011 -41.714 1.00 31.55 ? 425 ASN B CB 1 ATOM 6464 C CG . ASN B 1 427 ? -29.063 33.178 -42.523 1.00 44.51 ? 425 ASN B CG 1 ATOM 6465 O OD1 . ASN B 1 427 ? -28.539 34.295 -42.719 1.00 45.12 ? 425 ASN B OD1 1 ATOM 6466 N ND2 . ASN B 1 427 ? -28.534 32.065 -42.983 1.00 27.82 ? 425 ASN B ND2 1 ATOM 6467 N N . VAL B 1 428 ? -32.033 34.295 -38.777 1.00 43.52 ? 426 VAL B N 1 ATOM 6468 C CA . VAL B 1 428 ? -33.376 34.537 -38.258 1.00 43.14 ? 426 VAL B CA 1 ATOM 6469 C C . VAL B 1 428 ? -33.773 35.984 -38.590 1.00 49.94 ? 426 VAL B C 1 ATOM 6470 O O . VAL B 1 428 ? -32.914 36.873 -38.677 1.00 48.12 ? 426 VAL B O 1 ATOM 6471 C CB . VAL B 1 428 ? -33.550 34.214 -36.740 1.00 45.85 ? 426 VAL B CB 1 ATOM 6472 C CG1 . VAL B 1 428 ? -33.326 32.733 -36.444 1.00 45.36 ? 426 VAL B CG1 1 ATOM 6473 C CG2 . VAL B 1 428 ? -32.686 35.110 -35.833 1.00 45.03 ? 426 VAL B CG2 1 ATOM 6474 N N . LYS B 1 429 ? -35.073 36.201 -38.797 1.00 49.84 ? 427 LYS B N 1 ATOM 6475 C CA . LYS B 1 429 ? -35.646 37.524 -39.051 1.00 50.23 ? 427 LYS B CA 1 ATOM 6476 C C . LYS B 1 429 ? -37.113 37.466 -38.678 1.00 54.92 ? 427 LYS B C 1 ATOM 6477 O O . LYS B 1 429 ? -37.936 37.026 -39.475 1.00 55.70 ? 427 LYS B O 1 ATOM 6478 C CB . LYS B 1 429 ? -35.439 37.993 -40.503 1.00 51.68 ? 427 LYS B CB 1 ATOM 6479 C CG . LYS B 1 429 ? -35.499 39.509 -40.656 1.00 58.87 ? 427 LYS B CG 1 ATOM 6480 C CD . LYS B 1 429 ? -35.358 39.897 -42.118 1.00 66.09 ? 427 LYS B CD 1 ATOM 6481 C CE . LYS B 1 429 ? -36.086 41.171 -42.463 1.00 77.41 ? 427 LYS B CE 1 ATOM 6482 N NZ . LYS B 1 429 ? -35.970 41.485 -43.911 1.00 91.54 ? 427 LYS B NZ 1 ATOM 6483 N N . PHE B 1 430 ? -37.434 37.872 -37.449 1.00 50.47 ? 428 PHE B N 1 ATOM 6484 C CA . PHE B 1 430 ? -38.810 37.862 -36.961 1.00 49.48 ? 428 PHE B CA 1 ATOM 6485 C C . PHE B 1 430 ? -39.103 39.093 -36.138 1.00 54.10 ? 428 PHE B C 1 ATOM 6486 O O . PHE B 1 430 ? -38.179 39.706 -35.587 1.00 51.83 ? 428 PHE B O 1 ATOM 6487 C CB . PHE B 1 430 ? -39.098 36.581 -36.154 1.00 50.85 ? 428 PHE B CB 1 ATOM 6488 C CG . PHE B 1 430 ? -38.278 36.386 -34.893 1.00 52.64 ? 428 PHE B CG 1 ATOM 6489 C CD1 . PHE B 1 430 ? -36.993 35.844 -34.951 1.00 55.72 ? 428 PHE B CD1 1 ATOM 6490 C CD2 . PHE B 1 430 ? -38.809 36.692 -33.644 1.00 54.76 ? 428 PHE B CD2 1 ATOM 6491 C CE1 . PHE B 1 430 ? -36.248 35.644 -33.794 1.00 56.04 ? 428 PHE B CE1 1 ATOM 6492 C CE2 . PHE B 1 430 ? -38.064 36.483 -32.481 1.00 57.78 ? 428 PHE B CE2 1 ATOM 6493 C CZ . PHE B 1 430 ? -36.792 35.956 -32.565 1.00 56.12 ? 428 PHE B CZ 1 ATOM 6494 N N . ASP B 1 431 ? -40.404 39.428 -36.008 1.00 53.52 ? 429 ASP B N 1 ATOM 6495 C CA . ASP B 1 431 ? -40.833 40.547 -35.171 1.00 54.61 ? 429 ASP B CA 1 ATOM 6496 C C . ASP B 1 431 ? -40.583 40.172 -33.718 1.00 58.15 ? 429 ASP B C 1 ATOM 6497 O O . ASP B 1 431 ? -41.019 39.088 -33.288 1.00 57.77 ? 429 ASP B O 1 ATOM 6498 C CB . ASP B 1 431 ? -42.322 40.876 -35.399 1.00 57.27 ? 429 ASP B CB 1 ATOM 6499 C CG . ASP B 1 431 ? -42.634 41.428 -36.774 1.00 79.55 ? 429 ASP B CG 1 ATOM 6500 O OD1 . ASP B 1 431 ? -41.782 42.165 -37.331 1.00 83.75 ? 429 ASP B OD1 1 ATOM 6501 O OD2 . ASP B 1 431 ? -43.740 41.162 -37.279 1.00 87.93 ? 429 ASP B OD2 1 ATOM 6502 N N . ALA B 1 432 ? -39.827 41.029 -32.990 1.00 53.78 ? 430 ALA B N 1 ATOM 6503 C CA . ALA B 1 432 ? -39.515 40.829 -31.569 1.00 53.69 ? 430 ALA B CA 1 ATOM 6504 C C . ALA B 1 432 ? -40.811 40.639 -30.773 1.00 59.53 ? 430 ALA B C 1 ATOM 6505 O O . ALA B 1 432 ? -41.756 41.416 -30.985 1.00 60.66 ? 430 ALA B O 1 ATOM 6506 C CB . ALA B 1 432 ? -38.744 42.019 -31.027 1.00 54.38 ? 430 ALA B CB 1 ATOM 6507 N N . PRO B 1 433 ? -40.943 39.582 -29.929 1.00 55.73 ? 431 PRO B N 1 ATOM 6508 C CA . PRO B 1 433 ? -42.219 39.396 -29.205 1.00 55.10 ? 431 PRO B CA 1 ATOM 6509 C C . PRO B 1 433 ? -42.440 40.442 -28.112 1.00 57.38 ? 431 PRO B C 1 ATOM 6510 O O . PRO B 1 433 ? -41.489 41.123 -27.694 1.00 57.09 ? 431 PRO B O 1 ATOM 6511 C CB . PRO B 1 433 ? -42.129 37.966 -28.652 1.00 56.23 ? 431 PRO B CB 1 ATOM 6512 C CG . PRO B 1 433 ? -40.829 37.408 -29.175 1.00 60.23 ? 431 PRO B CG 1 ATOM 6513 C CD . PRO B 1 433 ? -39.963 38.550 -29.541 1.00 56.23 ? 431 PRO B CD 1 ATOM 6514 N N . PHE B 1 434 ? -43.717 40.610 -27.712 1.00 52.39 ? 432 PHE B N 1 ATOM 6515 C CA . PHE B 1 434 ? -44.197 41.515 -26.658 1.00 51.60 ? 432 PHE B CA 1 ATOM 6516 C C . PHE B 1 434 ? -43.765 42.984 -26.867 1.00 57.41 ? 432 PHE B C 1 ATOM 6517 O O . PHE B 1 434 ? -43.759 43.769 -25.913 1.00 58.39 ? 432 PHE B O 1 ATOM 6518 C CB . PHE B 1 434 ? -43.801 40.990 -25.250 1.00 52.46 ? 432 PHE B CB 1 ATOM 6519 C CG . PHE B 1 434 ? -43.982 39.499 -25.036 1.00 53.96 ? 432 PHE B CG 1 ATOM 6520 C CD1 . PHE B 1 434 ? -45.228 38.969 -24.719 1.00 56.10 ? 432 PHE B CD1 1 ATOM 6521 C CD2 . PHE B 1 434 ? -42.898 38.629 -25.123 1.00 56.41 ? 432 PHE B CD2 1 ATOM 6522 C CE1 . PHE B 1 434 ? -45.391 37.598 -24.501 1.00 56.74 ? 432 PHE B CE1 1 ATOM 6523 C CE2 . PHE B 1 434 ? -43.064 37.252 -24.928 1.00 58.64 ? 432 PHE B CE2 1 ATOM 6524 C CZ . PHE B 1 434 ? -44.309 36.747 -24.610 1.00 56.74 ? 432 PHE B CZ 1 ATOM 6525 N N . ARG B 1 435 ? -43.430 43.357 -28.107 1.00 54.60 ? 433 ARG B N 1 ATOM 6526 C CA . ARG B 1 435 ? -42.972 44.712 -28.422 1.00 55.26 ? 433 ARG B CA 1 ATOM 6527 C C . ARG B 1 435 ? -44.111 45.748 -28.346 1.00 61.89 ? 433 ARG B C 1 ATOM 6528 O O . ARG B 1 435 ? -45.261 45.382 -28.591 1.00 61.17 ? 433 ARG B O 1 ATOM 6529 C CB . ARG B 1 435 ? -42.215 44.763 -29.783 1.00 54.08 ? 433 ARG B CB 1 ATOM 6530 C CG . ARG B 1 435 ? -43.080 44.596 -31.032 1.00 54.00 ? 433 ARG B CG 1 ATOM 6531 C CD . ARG B 1 435 ? -42.266 44.539 -32.312 1.00 63.07 ? 433 ARG B CD 1 ATOM 6532 N NE . ARG B 1 435 ? -43.117 44.730 -33.496 1.00 67.31 ? 433 ARG B NE 1 ATOM 6533 C CZ . ARG B 1 435 ? -42.716 44.603 -34.763 1.00 69.67 ? 433 ARG B CZ 1 ATOM 6534 N NH1 . ARG B 1 435 ? -43.566 44.810 -35.757 1.00 46.21 ? 433 ARG B NH1 1 ATOM 6535 N NH2 . ARG B 1 435 ? -41.457 44.287 -35.043 1.00 52.40 ? 433 ARG B NH2 1 ATOM 6536 N N . PRO B 1 436 ? -43.828 47.040 -28.032 1.00 61.04 ? 434 PRO B N 1 ATOM 6537 C CA . PRO B 1 436 ? -44.910 48.045 -28.037 1.00 61.88 ? 434 PRO B CA 1 ATOM 6538 C C . PRO B 1 436 ? -45.462 48.289 -29.447 1.00 72.67 ? 434 PRO B C 1 ATOM 6539 O O . PRO B 1 436 ? -44.850 47.879 -30.443 1.00 71.93 ? 434 PRO B O 1 ATOM 6540 C CB . PRO B 1 436 ? -44.233 49.315 -27.501 1.00 63.06 ? 434 PRO B CB 1 ATOM 6541 C CG . PRO B 1 436 ? -42.903 48.884 -26.967 1.00 67.25 ? 434 PRO B CG 1 ATOM 6542 C CD . PRO B 1 436 ? -42.523 47.657 -27.719 1.00 62.63 ? 434 PRO B CD 1 ATOM 6543 N N . ALA B 1 437 ? -46.633 48.959 -29.532 1.00 74.29 ? 435 ALA B N 1 ATOM 6544 C CA . ALA B 1 437 ? -47.263 49.316 -30.811 1.00 75.23 ? 435 ALA B CA 1 ATOM 6545 C C . ALA B 1 437 ? -46.416 50.377 -31.572 1.00 80.88 ? 435 ALA B C 1 ATOM 6546 O O . ALA B 1 437 ? -46.325 50.317 -32.806 1.00 79.32 ? 435 ALA B O 1 ATOM 6547 C CB . ALA B 1 437 ? -48.687 49.813 -30.580 1.00 75.66 ? 435 ALA B CB 1 ATOM 6548 N N . ASP B 1 438 ? -45.752 51.294 -30.821 1.00 80.34 ? 436 ASP B N 1 ATOM 6549 C CA . ASP B 1 438 ? -44.896 52.371 -31.357 1.00 81.80 ? 436 ASP B CA 1 ATOM 6550 C C . ASP B 1 438 ? -43.684 51.847 -32.154 1.00 89.28 ? 436 ASP B C 1 ATOM 6551 O O . ASP B 1 438 ? -43.614 52.062 -33.376 1.00 89.14 ? 436 ASP B O 1 ATOM 6552 C CB . ASP B 1 438 ? -44.446 53.341 -30.243 1.00 83.31 ? 436 ASP B CB 1 ATOM 6553 N N . THR B 1 439 ? -42.761 51.133 -31.466 1.00 86.96 ? 437 THR B N 1 ATOM 6554 C CA . THR B 1 439 ? -41.546 50.582 -32.074 1.00 87.27 ? 437 THR B CA 1 ATOM 6555 C C . THR B 1 439 ? -41.805 49.252 -32.768 1.00 89.48 ? 437 THR B C 1 ATOM 6556 O O . THR B 1 439 ? -42.480 48.383 -32.209 1.00 89.07 ? 437 THR B O 1 ATOM 6557 C CB . THR B 1 439 ? -40.387 50.458 -31.044 1.00 102.12 ? 437 THR B CB 1 ATOM 6558 O OG1 . THR B 1 439 ? -40.718 49.490 -30.042 1.00 102.44 ? 437 THR B OG1 1 ATOM 6559 C CG2 . THR B 1 439 ? -39.987 51.803 -30.403 1.00 101.59 ? 437 THR B CG2 1 ATOM 6560 N N . HIS B 1 440 ? -41.250 49.094 -33.980 1.00 84.40 ? 438 HIS B N 1 ATOM 6561 C CA . HIS B 1 440 ? -41.346 47.847 -34.728 1.00 83.24 ? 438 HIS B CA 1 ATOM 6562 C C . HIS B 1 440 ? -39.934 47.262 -34.921 1.00 81.13 ? 438 HIS B C 1 ATOM 6563 O O . HIS B 1 440 ? -39.251 47.515 -35.926 1.00 80.81 ? 438 HIS B O 1 ATOM 6564 C CB . HIS B 1 440 ? -42.193 47.958 -36.014 1.00 84.94 ? 438 HIS B CB 1 ATOM 6565 C CG . HIS B 1 440 ? -41.889 49.118 -36.920 1.00 89.05 ? 438 HIS B CG 1 ATOM 6566 N ND1 . HIS B 1 440 ? -42.255 50.417 -36.587 1.00 91.01 ? 438 HIS B ND1 1 ATOM 6567 C CD2 . HIS B 1 440 ? -41.379 49.119 -38.175 1.00 90.84 ? 438 HIS B CD2 1 ATOM 6568 C CE1 . HIS B 1 440 ? -41.894 51.166 -37.616 1.00 90.34 ? 438 HIS B CE1 1 ATOM 6569 N NE2 . HIS B 1 440 ? -41.370 50.429 -38.598 1.00 90.68 ? 438 HIS B NE2 1 ATOM 6570 N N . ASN B 1 441 ? -39.495 46.525 -33.877 1.00 71.91 ? 439 ASN B N 1 ATOM 6571 C CA . ASN B 1 441 ? -38.179 45.906 -33.733 1.00 68.92 ? 439 ASN B CA 1 ATOM 6572 C C . ASN B 1 441 ? -38.167 44.487 -34.219 1.00 67.64 ? 439 ASN B C 1 ATOM 6573 O O . ASN B 1 441 ? -39.037 43.684 -33.878 1.00 67.17 ? 439 ASN B O 1 ATOM 6574 C CB . ASN B 1 441 ? -37.729 45.872 -32.258 1.00 67.94 ? 439 ASN B CB 1 ATOM 6575 C CG . ASN B 1 441 ? -37.896 47.143 -31.482 1.00 83.52 ? 439 ASN B CG 1 ATOM 6576 O OD1 . ASN B 1 441 ? -36.959 47.929 -31.332 1.00 82.45 ? 439 ASN B OD1 1 ATOM 6577 N ND2 . ASN B 1 441 ? -39.074 47.333 -30.912 1.00 70.08 ? 439 ASN B ND2 1 ATOM 6578 N N . GLU B 1 442 ? -37.117 44.148 -34.928 1.00 60.79 ? 440 GLU B N 1 ATOM 6579 C CA . GLU B 1 442 ? -36.912 42.788 -35.395 1.00 58.77 ? 440 GLU B CA 1 ATOM 6580 C C . GLU B 1 442 ? -35.777 42.163 -34.603 1.00 57.11 ? 440 GLU B C 1 ATOM 6581 O O . GLU B 1 442 ? -34.891 42.872 -34.110 1.00 55.00 ? 440 GLU B O 1 ATOM 6582 C CB . GLU B 1 442 ? -36.544 42.767 -36.891 1.00 60.04 ? 440 GLU B CB 1 ATOM 6583 C CG . GLU B 1 442 ? -37.688 43.113 -37.814 1.00 68.91 ? 440 GLU B CG 1 ATOM 6584 C CD . GLU B 1 442 ? -37.422 42.762 -39.259 1.00 85.65 ? 440 GLU B CD 1 ATOM 6585 O OE1 . GLU B 1 442 ? -36.673 43.513 -39.926 1.00 71.26 ? 440 GLU B OE1 1 ATOM 6586 O OE2 . GLU B 1 442 ? -37.985 41.748 -39.729 1.00 83.01 ? 440 GLU B OE2 1 ATOM 6587 N N . VAL B 1 443 ? -35.812 40.836 -34.480 1.00 52.09 ? 441 VAL B N 1 ATOM 6588 C CA . VAL B 1 443 ? -34.718 40.076 -33.888 1.00 51.04 ? 441 VAL B CA 1 ATOM 6589 C C . VAL B 1 443 ? -33.941 39.566 -35.111 1.00 52.58 ? 441 VAL B C 1 ATOM 6590 O O . VAL B 1 443 ? -34.481 38.815 -35.926 1.00 52.72 ? 441 VAL B O 1 ATOM 6591 C CB . VAL B 1 443 ? -35.152 38.947 -32.914 1.00 53.88 ? 441 VAL B CB 1 ATOM 6592 C CG1 . VAL B 1 443 ? -33.938 38.270 -32.276 1.00 53.28 ? 441 VAL B CG1 1 ATOM 6593 C CG2 . VAL B 1 443 ? -36.091 39.476 -31.839 1.00 53.24 ? 441 VAL B CG2 1 ATOM 6594 N N . ARG B 1 444 ? -32.736 40.078 -35.296 1.00 48.55 ? 442 ARG B N 1 ATOM 6595 C CA . ARG B 1 444 ? -31.883 39.719 -36.426 1.00 49.56 ? 442 ARG B CA 1 ATOM 6596 C C . ARG B 1 444 ? -30.414 39.859 -36.066 1.00 52.89 ? 442 ARG B C 1 ATOM 6597 O O . ARG B 1 444 ? -30.044 40.756 -35.306 1.00 53.07 ? 442 ARG B O 1 ATOM 6598 C CB . ARG B 1 444 ? -32.255 40.529 -37.701 1.00 51.45 ? 442 ARG B CB 1 ATOM 6599 C CG . ARG B 1 444 ? -31.896 42.033 -37.659 1.00 67.36 ? 442 ARG B CG 1 ATOM 6600 C CD . ARG B 1 444 ? -32.908 42.946 -38.345 1.00 81.01 ? 442 ARG B CD 1 ATOM 6601 N NE . ARG B 1 444 ? -33.200 42.537 -39.722 1.00 94.30 ? 442 ARG B NE 1 ATOM 6602 C CZ . ARG B 1 444 ? -32.538 42.957 -40.794 1.00 106.65 ? 442 ARG B CZ 1 ATOM 6603 N NH1 . ARG B 1 444 ? -31.532 43.815 -40.670 1.00 99.88 ? 442 ARG B NH1 1 ATOM 6604 N NH2 . ARG B 1 444 ? -32.879 42.526 -42.000 1.00 85.32 ? 442 ARG B NH2 1 ATOM 6605 N N . PHE B 1 445 ? -29.578 38.979 -36.605 1.00 48.45 ? 443 PHE B N 1 ATOM 6606 C CA . PHE B 1 445 ? -28.139 39.064 -36.353 1.00 48.04 ? 443 PHE B CA 1 ATOM 6607 C C . PHE B 1 445 ? -27.435 39.600 -37.594 1.00 53.15 ? 443 PHE B C 1 ATOM 6608 O O . PHE B 1 445 ? -27.814 39.260 -38.732 1.00 51.91 ? 443 PHE B O 1 ATOM 6609 C CB . PHE B 1 445 ? -27.547 37.690 -35.960 1.00 49.31 ? 443 PHE B CB 1 ATOM 6610 C CG . PHE B 1 445 ? -28.144 37.130 -34.699 1.00 50.23 ? 443 PHE B CG 1 ATOM 6611 C CD1 . PHE B 1 445 ? -29.280 36.327 -34.744 1.00 53.28 ? 443 PHE B CD1 1 ATOM 6612 C CD2 . PHE B 1 445 ? -27.627 37.475 -33.454 1.00 50.71 ? 443 PHE B CD2 1 ATOM 6613 C CE1 . PHE B 1 445 ? -29.880 35.872 -33.562 1.00 53.49 ? 443 PHE B CE1 1 ATOM 6614 C CE2 . PHE B 1 445 ? -28.238 37.032 -32.277 1.00 52.31 ? 443 PHE B CE2 1 ATOM 6615 C CZ . PHE B 1 445 ? -29.355 36.235 -32.339 1.00 50.40 ? 443 PHE B CZ 1 ATOM 6616 N N . ASP B 1 446 ? -26.391 40.420 -37.377 1.00 49.53 ? 444 ASP B N 1 ATOM 6617 C CA . ASP B 1 446 ? -25.599 40.887 -38.494 1.00 48.53 ? 444 ASP B CA 1 ATOM 6618 C C . ASP B 1 446 ? -24.571 39.793 -38.860 1.00 53.15 ? 444 ASP B C 1 ATOM 6619 O O . ASP B 1 446 ? -24.641 38.681 -38.325 1.00 50.95 ? 444 ASP B O 1 ATOM 6620 C CB . ASP B 1 446 ? -24.996 42.289 -38.222 1.00 49.93 ? 444 ASP B CB 1 ATOM 6621 C CG . ASP B 1 446 ? -23.815 42.417 -37.271 1.00 59.37 ? 444 ASP B CG 1 ATOM 6622 O OD1 . ASP B 1 446 ? -23.135 41.407 -37.026 1.00 61.22 ? 444 ASP B OD1 1 ATOM 6623 O OD2 . ASP B 1 446 ? -23.514 43.557 -36.849 1.00 62.73 ? 444 ASP B OD2 1 ATOM 6624 N N . ARG B 1 447 ? -23.620 40.127 -39.756 1.00 53.25 ? 445 ARG B N 1 ATOM 6625 C CA . ARG B 1 447 ? -22.523 39.296 -40.282 1.00 54.15 ? 445 ARG B CA 1 ATOM 6626 C C . ARG B 1 447 ? -21.641 38.741 -39.171 1.00 57.88 ? 445 ARG B C 1 ATOM 6627 O O . ARG B 1 447 ? -21.169 37.607 -39.281 1.00 57.82 ? 445 ARG B O 1 ATOM 6628 C CB . ARG B 1 447 ? -21.665 40.170 -41.210 1.00 58.51 ? 445 ARG B CB 1 ATOM 6629 C CG . ARG B 1 447 ? -20.758 39.427 -42.207 1.00 75.52 ? 445 ARG B CG 1 ATOM 6630 C CD . ARG B 1 447 ? -20.416 40.276 -43.435 1.00 85.02 ? 445 ARG B CD 1 ATOM 6631 N NE . ARG B 1 447 ? -20.425 41.718 -43.152 1.00 94.03 ? 445 ARG B NE 1 ATOM 6632 C CZ . ARG B 1 447 ? -19.356 42.426 -42.805 1.00 109.11 ? 445 ARG B CZ 1 ATOM 6633 N NH1 . ARG B 1 447 ? -18.163 41.846 -42.723 1.00 100.95 ? 445 ARG B NH1 1 ATOM 6634 N NH2 . ARG B 1 447 ? -19.465 43.726 -42.555 1.00 89.40 ? 445 ARG B NH2 1 ATOM 6635 N N . PHE B 1 448 ? -21.447 39.551 -38.100 1.00 52.71 ? 446 PHE B N 1 ATOM 6636 C CA . PHE B 1 448 ? -20.622 39.295 -36.918 1.00 51.06 ? 446 PHE B CA 1 ATOM 6637 C C . PHE B 1 448 ? -21.357 38.702 -35.710 1.00 51.35 ? 446 PHE B C 1 ATOM 6638 O O . PHE B 1 448 ? -20.788 38.675 -34.606 1.00 52.72 ? 446 PHE B O 1 ATOM 6639 C CB . PHE B 1 448 ? -19.976 40.620 -36.479 1.00 52.80 ? 446 PHE B CB 1 ATOM 6640 C CG . PHE B 1 448 ? -19.320 41.427 -37.568 1.00 54.14 ? 446 PHE B CG 1 ATOM 6641 C CD1 . PHE B 1 448 ? -18.410 40.838 -38.441 1.00 57.08 ? 446 PHE B CD1 1 ATOM 6642 C CD2 . PHE B 1 448 ? -19.570 42.786 -37.690 1.00 56.04 ? 446 PHE B CD2 1 ATOM 6643 C CE1 . PHE B 1 448 ? -17.792 41.590 -39.436 1.00 57.91 ? 446 PHE B CE1 1 ATOM 6644 C CE2 . PHE B 1 448 ? -18.949 43.539 -38.683 1.00 58.70 ? 446 PHE B CE2 1 ATOM 6645 C CZ . PHE B 1 448 ? -18.066 42.935 -39.552 1.00 56.84 ? 446 PHE B CZ 1 ATOM 6646 N N . GLY B 1 449 ? -22.615 38.315 -35.896 1.00 44.04 ? 447 GLY B N 1 ATOM 6647 C CA . GLY B 1 449 ? -23.473 37.797 -34.830 1.00 42.57 ? 447 GLY B CA 1 ATOM 6648 C C . GLY B 1 449 ? -23.996 38.823 -33.825 1.00 43.26 ? 447 GLY B C 1 ATOM 6649 O O . GLY B 1 449 ? -24.545 38.438 -32.789 1.00 42.88 ? 447 GLY B O 1 ATOM 6650 N N . ASP B 1 450 ? -23.886 40.136 -34.142 1.00 37.18 ? 448 ASP B N 1 ATOM 6651 C CA . ASP B 1 450 ? -24.276 41.242 -33.269 1.00 36.39 ? 448 ASP B CA 1 ATOM 6652 C C . ASP B 1 450 ? -25.672 41.853 -33.504 1.00 43.46 ? 448 ASP B C 1 ATOM 6653 O O . ASP B 1 450 ? -26.239 41.781 -34.605 1.00 43.33 ? 448 ASP B O 1 ATOM 6654 C CB . ASP B 1 450 ? -23.214 42.347 -33.354 1.00 37.34 ? 448 ASP B CB 1 ATOM 6655 C CG . ASP B 1 450 ? -21.843 41.913 -32.883 1.00 54.88 ? 448 ASP B CG 1 ATOM 6656 O OD1 . ASP B 1 450 ? -21.769 41.013 -32.033 1.00 61.24 ? 448 ASP B OD1 1 ATOM 6657 O OD2 . ASP B 1 450 ? -20.841 42.453 -33.390 1.00 56.06 ? 448 ASP B OD2 1 ATOM 6658 N N . GLY B 1 451 ? -26.165 42.508 -32.458 1.00 42.43 ? 449 GLY B N 1 ATOM 6659 C CA . GLY B 1 451 ? -27.405 43.264 -32.456 1.00 44.03 ? 449 GLY B CA 1 ATOM 6660 C C . GLY B 1 451 ? -27.220 44.686 -32.975 1.00 52.71 ? 449 GLY B C 1 ATOM 6661 O O . GLY B 1 451 ? -26.097 45.144 -33.225 1.00 51.68 ? 449 GLY B O 1 ATOM 6662 N N . ILE B 1 452 ? -28.343 45.388 -33.163 1.00 54.05 ? 450 ILE B N 1 ATOM 6663 C CA . ILE B 1 452 ? -28.384 46.746 -33.695 1.00 55.79 ? 450 ILE B CA 1 ATOM 6664 C C . ILE B 1 452 ? -27.980 47.744 -32.620 1.00 60.12 ? 450 ILE B C 1 ATOM 6665 O O . ILE B 1 452 ? -28.469 47.647 -31.495 1.00 60.49 ? 450 ILE B O 1 ATOM 6666 C CB . ILE B 1 452 ? -29.781 46.994 -34.351 1.00 60.13 ? 450 ILE B CB 1 ATOM 6667 C CG1 . ILE B 1 452 ? -29.760 46.488 -35.820 1.00 62.31 ? 450 ILE B CG1 1 ATOM 6668 C CG2 . ILE B 1 452 ? -30.186 48.454 -34.331 1.00 60.90 ? 450 ILE B CG2 1 ATOM 6669 C CD1 . ILE B 1 452 ? -31.074 45.730 -36.357 1.00 73.33 ? 450 ILE B CD1 1 ATOM 6670 N N . GLY B 1 453 ? -27.083 48.665 -32.978 1.00 56.70 ? 451 GLY B N 1 ATOM 6671 C CA . GLY B 1 453 ? -26.576 49.723 -32.105 1.00 57.30 ? 451 GLY B CA 1 ATOM 6672 C C . GLY B 1 453 ? -27.598 50.773 -31.690 1.00 63.15 ? 451 GLY B C 1 ATOM 6673 O O . GLY B 1 453 ? -27.494 51.938 -32.089 1.00 64.04 ? 451 GLY B O 1 ATOM 6674 N N . ARG B 1 454 ? -28.594 50.361 -30.881 1.00 59.42 ? 452 ARG B N 1 ATOM 6675 C CA . ARG B 1 454 ? -29.663 51.197 -30.331 1.00 58.93 ? 452 ARG B CA 1 ATOM 6676 C C . ARG B 1 454 ? -29.480 51.357 -28.820 1.00 61.72 ? 452 ARG B C 1 ATOM 6677 O O . ARG B 1 454 ? -29.426 50.373 -28.070 1.00 60.43 ? 452 ARG B O 1 ATOM 6678 C CB . ARG B 1 454 ? -31.055 50.656 -30.680 1.00 58.43 ? 452 ARG B CB 1 ATOM 6679 C CG . ARG B 1 454 ? -31.490 51.029 -32.082 1.00 74.67 ? 452 ARG B CG 1 ATOM 6680 C CD . ARG B 1 454 ? -32.768 50.315 -32.481 1.00 90.49 ? 452 ARG B CD 1 ATOM 6681 N NE . ARG B 1 454 ? -33.178 50.712 -33.826 1.00 99.96 ? 452 ARG B NE 1 ATOM 6682 C CZ . ARG B 1 454 ? -34.069 50.063 -34.566 1.00 112.19 ? 452 ARG B CZ 1 ATOM 6683 N NH1 . ARG B 1 454 ? -34.649 48.959 -34.106 1.00 92.09 ? 452 ARG B NH1 1 ATOM 6684 N NH2 . ARG B 1 454 ? -34.381 50.506 -35.778 1.00 100.32 ? 452 ARG B NH2 1 ATOM 6685 N N . TYR B 1 455 ? -29.346 52.618 -28.400 1.00 57.16 ? 453 TYR B N 1 ATOM 6686 C CA . TYR B 1 455 ? -29.089 53.025 -27.039 1.00 56.22 ? 453 TYR B CA 1 ATOM 6687 C C . TYR B 1 455 ? -30.046 54.133 -26.680 1.00 60.54 ? 453 TYR B C 1 ATOM 6688 O O . TYR B 1 455 ? -30.523 54.848 -27.562 1.00 60.44 ? 453 TYR B O 1 ATOM 6689 C CB . TYR B 1 455 ? -27.643 53.532 -26.914 1.00 57.24 ? 453 TYR B CB 1 ATOM 6690 C CG . TYR B 1 455 ? -26.602 52.519 -27.340 1.00 59.40 ? 453 TYR B CG 1 ATOM 6691 C CD1 . TYR B 1 455 ? -26.196 52.423 -28.665 1.00 61.20 ? 453 TYR B CD1 1 ATOM 6692 C CD2 . TYR B 1 455 ? -26.005 51.672 -26.414 1.00 60.33 ? 453 TYR B CD2 1 ATOM 6693 C CE1 . TYR B 1 455 ? -25.269 51.465 -29.069 1.00 62.08 ? 453 TYR B CE1 1 ATOM 6694 C CE2 . TYR B 1 455 ? -25.061 50.726 -26.802 1.00 60.78 ? 453 TYR B CE2 1 ATOM 6695 C CZ . TYR B 1 455 ? -24.696 50.623 -28.133 1.00 66.16 ? 453 TYR B CZ 1 ATOM 6696 O OH . TYR B 1 455 ? -23.761 49.690 -28.523 1.00 66.57 ? 453 TYR B OH 1 ATOM 6697 N N . ASN B 1 456 ? -30.351 54.248 -25.376 1.00 55.66 ? 454 ASN B N 1 ATOM 6698 C CA . ASN B 1 456 ? -31.191 55.277 -24.798 1.00 53.90 ? 454 ASN B CA 1 ATOM 6699 C C . ASN B 1 456 ? -30.298 56.107 -23.925 1.00 56.01 ? 454 ASN B C 1 ATOM 6700 O O . ASN B 1 456 ? -29.502 55.561 -23.163 1.00 54.68 ? 454 ASN B O 1 ATOM 6701 C CB . ASN B 1 456 ? -32.328 54.674 -23.971 1.00 51.75 ? 454 ASN B CB 1 ATOM 6702 C CG . ASN B 1 456 ? -33.519 54.286 -24.792 1.00 66.52 ? 454 ASN B CG 1 ATOM 6703 O OD1 . ASN B 1 456 ? -33.841 54.939 -25.789 1.00 65.78 ? 454 ASN B OD1 1 ATOM 6704 N ND2 . ASN B 1 456 ? -34.216 53.223 -24.385 1.00 50.86 ? 454 ASN B ND2 1 ATOM 6705 N N . ILE B 1 457 ? -30.415 57.432 -24.049 1.00 53.09 ? 455 ILE B N 1 ATOM 6706 C CA . ILE B 1 457 ? -29.642 58.390 -23.258 1.00 52.45 ? 455 ILE B CA 1 ATOM 6707 C C . ILE B 1 457 ? -30.536 58.931 -22.157 1.00 55.40 ? 455 ILE B C 1 ATOM 6708 O O . ILE B 1 457 ? -31.709 59.229 -22.415 1.00 54.55 ? 455 ILE B O 1 ATOM 6709 C CB . ILE B 1 457 ? -29.031 59.506 -24.131 1.00 55.29 ? 455 ILE B CB 1 ATOM 6710 C CG1 . ILE B 1 457 ? -28.418 58.911 -25.420 1.00 56.35 ? 455 ILE B CG1 1 ATOM 6711 C CG2 . ILE B 1 457 ? -27.977 60.259 -23.338 1.00 55.35 ? 455 ILE B CG2 1 ATOM 6712 C CD1 . ILE B 1 457 ? -28.383 59.833 -26.563 1.00 67.25 ? 455 ILE B CD1 1 ATOM 6713 N N . PHE B 1 458 ? -29.993 58.999 -20.921 1.00 51.09 ? 456 PHE B N 1 ATOM 6714 C CA . PHE B 1 458 ? -30.695 59.465 -19.724 1.00 50.65 ? 456 PHE B CA 1 ATOM 6715 C C . PHE B 1 458 ? -29.883 60.517 -19.023 1.00 57.51 ? 456 PHE B C 1 ATOM 6716 O O . PHE B 1 458 ? -28.667 60.586 -19.223 1.00 55.72 ? 456 PHE B O 1 ATOM 6717 C CB . PHE B 1 458 ? -30.895 58.306 -18.703 1.00 51.66 ? 456 PHE B CB 1 ATOM 6718 C CG . PHE B 1 458 ? -31.782 57.166 -19.137 1.00 52.75 ? 456 PHE B CG 1 ATOM 6719 C CD1 . PHE B 1 458 ? -33.163 57.237 -18.979 1.00 55.05 ? 456 PHE B CD1 1 ATOM 6720 C CD2 . PHE B 1 458 ? -31.240 56.019 -19.716 1.00 53.55 ? 456 PHE B CD2 1 ATOM 6721 C CE1 . PHE B 1 458 ? -33.988 56.189 -19.415 1.00 54.87 ? 456 PHE B CE1 1 ATOM 6722 C CE2 . PHE B 1 458 ? -32.071 54.993 -20.180 1.00 55.40 ? 456 PHE B CE2 1 ATOM 6723 C CZ . PHE B 1 458 ? -33.434 55.074 -20.006 1.00 52.89 ? 456 PHE B CZ 1 ATOM 6724 N N . THR B 1 459 ? -30.556 61.286 -18.134 1.00 58.23 ? 457 THR B N 1 ATOM 6725 C CA . THR B 1 459 ? -29.950 62.222 -17.178 1.00 59.33 ? 457 THR B CA 1 ATOM 6726 C C . THR B 1 459 ? -30.545 62.029 -15.788 1.00 65.07 ? 457 THR B C 1 ATOM 6727 O O . THR B 1 459 ? -31.738 61.756 -15.658 1.00 65.01 ? 457 THR B O 1 ATOM 6728 C CB . THR B 1 459 ? -29.928 63.698 -17.620 1.00 64.61 ? 457 THR B CB 1 ATOM 6729 O OG1 . THR B 1 459 ? -28.910 64.327 -16.846 1.00 66.15 ? 457 THR B OG1 1 ATOM 6730 C CG2 . THR B 1 459 ? -31.247 64.428 -17.374 1.00 59.73 ? 457 THR B CG2 1 ATOM 6731 N N . TYR B 1 460 ? -29.710 62.152 -14.764 1.00 63.98 ? 458 TYR B N 1 ATOM 6732 C CA . TYR B 1 460 ? -30.136 62.055 -13.374 1.00 65.37 ? 458 TYR B CA 1 ATOM 6733 C C . TYR B 1 460 ? -30.381 63.486 -12.898 1.00 72.34 ? 458 TYR B C 1 ATOM 6734 O O . TYR B 1 460 ? -29.474 64.327 -12.960 1.00 72.24 ? 458 TYR B O 1 ATOM 6735 C CB . TYR B 1 460 ? -29.048 61.383 -12.522 1.00 66.83 ? 458 TYR B CB 1 ATOM 6736 C CG . TYR B 1 460 ? -29.557 60.804 -11.220 1.00 69.30 ? 458 TYR B CG 1 ATOM 6737 C CD1 . TYR B 1 460 ? -30.319 59.642 -11.204 1.00 71.66 ? 458 TYR B CD1 1 ATOM 6738 C CD2 . TYR B 1 460 ? -29.218 61.378 -9.998 1.00 70.02 ? 458 TYR B CD2 1 ATOM 6739 C CE1 . TYR B 1 460 ? -30.741 59.068 -10.009 1.00 72.19 ? 458 TYR B CE1 1 ATOM 6740 C CE2 . TYR B 1 460 ? -29.660 60.828 -8.794 1.00 70.71 ? 458 TYR B CE2 1 ATOM 6741 C CZ . TYR B 1 460 ? -30.422 59.669 -8.806 1.00 76.32 ? 458 TYR B CZ 1 ATOM 6742 O OH . TYR B 1 460 ? -30.856 59.081 -7.643 1.00 74.47 ? 458 TYR B OH 1 ATOM 6743 N N . LEU B 1 461 ? -31.611 63.771 -12.461 1.00 70.86 ? 459 LEU B N 1 ATOM 6744 C CA . LEU B 1 461 ? -32.007 65.103 -12.006 1.00 71.48 ? 459 LEU B CA 1 ATOM 6745 C C . LEU B 1 461 ? -32.708 65.134 -10.640 1.00 79.38 ? 459 LEU B C 1 ATOM 6746 O O . LEU B 1 461 ? -33.357 64.150 -10.258 1.00 79.43 ? 459 LEU B O 1 ATOM 6747 C CB . LEU B 1 461 ? -32.873 65.798 -13.077 1.00 71.31 ? 459 LEU B CB 1 ATOM 6748 C CG . LEU B 1 461 ? -34.056 65.024 -13.692 1.00 75.51 ? 459 LEU B CG 1 ATOM 6749 C CD1 . LEU B 1 461 ? -35.297 65.088 -12.810 1.00 75.75 ? 459 LEU B CD1 1 ATOM 6750 C CD2 . LEU B 1 461 ? -34.400 65.578 -15.047 1.00 76.20 ? 459 LEU B CD2 1 ATOM 6751 N N . ARG B 1 462 ? -32.590 66.286 -9.913 1.00 78.41 ? 460 ARG B N 1 ATOM 6752 C CA . ARG B 1 462 ? -33.285 66.514 -8.635 1.00 78.29 ? 460 ARG B CA 1 ATOM 6753 C C . ARG B 1 462 ? -34.676 66.983 -8.993 1.00 80.42 ? 460 ARG B C 1 ATOM 6754 O O . ARG B 1 462 ? -34.852 68.114 -9.441 1.00 80.07 ? 460 ARG B O 1 ATOM 6755 C CB . ARG B 1 462 ? -32.585 67.553 -7.738 1.00 79.40 ? 460 ARG B CB 1 ATOM 6756 C CG . ARG B 1 462 ? -33.126 67.545 -6.309 1.00 90.51 ? 460 ARG B CG 1 ATOM 6757 C CD . ARG B 1 462 ? -32.670 68.750 -5.505 1.00 97.50 ? 460 ARG B CD 1 ATOM 6758 N NE . ARG B 1 462 ? -33.465 68.947 -4.287 1.00 101.56 ? 460 ARG B NE 1 ATOM 6759 C CZ . ARG B 1 462 ? -34.652 69.553 -4.251 1.00 112.28 ? 460 ARG B CZ 1 ATOM 6760 N NH1 . ARG B 1 462 ? -35.292 69.702 -3.101 1.00 96.80 ? 460 ARG B NH1 1 ATOM 6761 N NH2 . ARG B 1 462 ? -35.207 70.011 -5.369 1.00 96.15 ? 460 ARG B NH2 1 ATOM 6762 N N . ALA B 1 463 ? -35.646 66.081 -8.865 1.00 76.06 ? 461 ALA B N 1 ATOM 6763 C CA . ALA B 1 463 ? -37.041 66.334 -9.164 1.00 75.32 ? 461 ALA B CA 1 ATOM 6764 C C . ALA B 1 463 ? -37.719 67.064 -7.995 1.00 79.52 ? 461 ALA B C 1 ATOM 6765 O O . ALA B 1 463 ? -37.042 67.612 -7.098 1.00 78.34 ? 461 ALA B O 1 ATOM 6766 C CB . ALA B 1 463 ? -37.748 65.025 -9.462 1.00 75.83 ? 461 ALA B CB 1 ATOM 6767 N N . GLY B 1 464 ? -39.052 67.085 -8.049 1.00 76.02 ? 462 GLY B N 1 ATOM 6768 C CA . GLY B 1 464 ? -39.899 67.712 -7.048 1.00 75.49 ? 462 GLY B CA 1 ATOM 6769 C C . GLY B 1 464 ? -39.831 67.056 -5.686 1.00 77.58 ? 462 GLY B C 1 ATOM 6770 O O . GLY B 1 464 ? -39.799 65.822 -5.562 1.00 75.49 ? 462 GLY B O 1 ATOM 6771 N N . SER B 1 465 ? -39.831 67.911 -4.655 1.00 74.35 ? 463 SER B N 1 ATOM 6772 C CA . SER B 1 465 ? -39.838 67.552 -3.239 1.00 73.86 ? 463 SER B CA 1 ATOM 6773 C C . SER B 1 465 ? -38.706 66.603 -2.860 1.00 75.23 ? 463 SER B C 1 ATOM 6774 O O . SER B 1 465 ? -38.958 65.516 -2.339 1.00 73.75 ? 463 SER B O 1 ATOM 6775 C CB . SER B 1 465 ? -41.210 67.022 -2.804 1.00 78.15 ? 463 SER B CB 1 ATOM 6776 O OG . SER B 1 465 ? -41.495 65.733 -3.325 1.00 88.58 ? 463 SER B OG 1 ATOM 6777 N N . GLY B 1 466 ? -37.478 67.037 -3.155 1.00 70.84 ? 464 GLY B N 1 ATOM 6778 C CA . GLY B 1 466 ? -36.231 66.354 -2.825 1.00 69.94 ? 464 GLY B CA 1 ATOM 6779 C C . GLY B 1 466 ? -36.035 64.942 -3.331 1.00 73.01 ? 464 GLY B C 1 ATOM 6780 O O . GLY B 1 466 ? -35.168 64.227 -2.825 1.00 72.78 ? 464 GLY B O 1 ATOM 6781 N N . ARG B 1 467 ? -36.816 64.529 -4.331 1.00 68.54 ? 465 ARG B N 1 ATOM 6782 C CA . ARG B 1 467 ? -36.688 63.193 -4.900 1.00 67.31 ? 465 ARG B CA 1 ATOM 6783 C C . ARG B 1 467 ? -35.765 63.256 -6.088 1.00 72.20 ? 465 ARG B C 1 ATOM 6784 O O . ARG B 1 467 ? -35.710 64.286 -6.756 1.00 71.48 ? 465 ARG B O 1 ATOM 6785 C CB . ARG B 1 467 ? -38.050 62.663 -5.314 1.00 63.64 ? 465 ARG B CB 1 ATOM 6786 C CG . ARG B 1 467 ? -38.960 62.421 -4.124 1.00 65.65 ? 465 ARG B CG 1 ATOM 6787 C CD . ARG B 1 467 ? -39.827 61.202 -4.342 1.00 63.50 ? 465 ARG B CD 1 ATOM 6788 N NE . ARG B 1 467 ? -40.577 60.855 -3.143 1.00 68.84 ? 465 ARG B NE 1 ATOM 6789 C CZ . ARG B 1 467 ? -41.745 61.391 -2.810 1.00 86.27 ? 465 ARG B CZ 1 ATOM 6790 N NH1 . ARG B 1 467 ? -42.307 62.314 -3.586 1.00 72.90 ? 465 ARG B NH1 1 ATOM 6791 N NH2 . ARG B 1 467 ? -42.358 61.015 -1.698 1.00 74.60 ? 465 ARG B NH2 1 ATOM 6792 N N . TYR B 1 468 ? -35.014 62.181 -6.336 1.00 70.44 ? 466 TYR B N 1 ATOM 6793 C CA . TYR B 1 468 ? -34.100 62.111 -7.479 1.00 71.17 ? 466 TYR B CA 1 ATOM 6794 C C . TYR B 1 468 ? -34.560 61.033 -8.441 1.00 72.97 ? 466 TYR B C 1 ATOM 6795 O O . TYR B 1 468 ? -35.007 59.970 -8.002 1.00 73.13 ? 466 TYR B O 1 ATOM 6796 C CB . TYR B 1 468 ? -32.672 61.810 -7.027 1.00 73.70 ? 466 TYR B CB 1 ATOM 6797 C CG . TYR B 1 468 ? -31.930 62.993 -6.459 1.00 77.85 ? 466 TYR B CG 1 ATOM 6798 C CD1 . TYR B 1 468 ? -31.237 63.870 -7.290 1.00 80.62 ? 466 TYR B CD1 1 ATOM 6799 C CD2 . TYR B 1 468 ? -31.885 63.220 -5.085 1.00 79.00 ? 466 TYR B CD2 1 ATOM 6800 C CE1 . TYR B 1 468 ? -30.517 64.946 -6.767 1.00 82.71 ? 466 TYR B CE1 1 ATOM 6801 C CE2 . TYR B 1 468 ? -31.171 64.293 -4.550 1.00 80.15 ? 466 TYR B CE2 1 ATOM 6802 C CZ . TYR B 1 468 ? -30.497 65.161 -5.396 1.00 90.21 ? 466 TYR B CZ 1 ATOM 6803 O OH . TYR B 1 468 ? -29.794 66.222 -4.877 1.00 92.86 ? 466 TYR B OH 1 ATOM 6804 N N . ARG B 1 469 ? -34.438 61.294 -9.745 1.00 66.81 ? 467 ARG B N 1 ATOM 6805 C CA . ARG B 1 469 ? -34.838 60.323 -10.758 1.00 65.37 ? 467 ARG B CA 1 ATOM 6806 C C . ARG B 1 469 ? -34.016 60.406 -12.053 1.00 68.18 ? 467 ARG B C 1 ATOM 6807 O O . ARG B 1 469 ? -33.339 61.409 -12.309 1.00 67.98 ? 467 ARG B O 1 ATOM 6808 C CB . ARG B 1 469 ? -36.357 60.410 -11.056 1.00 62.06 ? 467 ARG B CB 1 ATOM 6809 C CG . ARG B 1 469 ? -36.842 61.758 -11.557 1.00 67.55 ? 467 ARG B CG 1 ATOM 6810 C CD . ARG B 1 469 ? -37.858 61.603 -12.668 1.00 81.11 ? 467 ARG B CD 1 ATOM 6811 N NE . ARG B 1 469 ? -38.499 62.877 -12.990 1.00 96.08 ? 467 ARG B NE 1 ATOM 6812 C CZ . ARG B 1 469 ? -39.676 63.268 -12.509 1.00 118.34 ? 467 ARG B CZ 1 ATOM 6813 N NH1 . ARG B 1 469 ? -40.366 62.477 -11.692 1.00 107.40 ? 467 ARG B NH1 1 ATOM 6814 N NH2 . ARG B 1 469 ? -40.179 64.448 -12.847 1.00 109.11 ? 467 ARG B NH2 1 ATOM 6815 N N . TYR B 1 470 ? -34.114 59.346 -12.878 1.00 62.05 ? 468 TYR B N 1 ATOM 6816 C CA . TYR B 1 470 ? -33.500 59.279 -14.194 1.00 60.35 ? 468 TYR B CA 1 ATOM 6817 C C . TYR B 1 470 ? -34.548 59.686 -15.231 1.00 63.76 ? 468 TYR B C 1 ATOM 6818 O O . TYR B 1 470 ? -35.675 59.186 -15.193 1.00 62.73 ? 468 TYR B O 1 ATOM 6819 C CB . TYR B 1 470 ? -33.046 57.849 -14.498 1.00 60.36 ? 468 TYR B CB 1 ATOM 6820 C CG . TYR B 1 470 ? -31.811 57.387 -13.768 1.00 59.04 ? 468 TYR B CG 1 ATOM 6821 C CD1 . TYR B 1 470 ? -30.539 57.736 -14.222 1.00 60.41 ? 468 TYR B CD1 1 ATOM 6822 C CD2 . TYR B 1 470 ? -31.902 56.506 -12.695 1.00 58.33 ? 468 TYR B CD2 1 ATOM 6823 C CE1 . TYR B 1 470 ? -29.390 57.277 -13.579 1.00 59.57 ? 468 TYR B CE1 1 ATOM 6824 C CE2 . TYR B 1 470 ? -30.762 56.037 -12.048 1.00 58.89 ? 468 TYR B CE2 1 ATOM 6825 C CZ . TYR B 1 470 ? -29.507 56.422 -12.499 1.00 66.38 ? 468 TYR B CZ 1 ATOM 6826 O OH . TYR B 1 470 ? -28.375 55.941 -11.901 1.00 68.63 ? 468 TYR B OH 1 ATOM 6827 N N . GLN B 1 471 ? -34.169 60.558 -16.173 1.00 61.45 ? 469 GLN B N 1 ATOM 6828 C CA . GLN B 1 471 ? -35.052 61.029 -17.236 1.00 62.59 ? 469 GLN B CA 1 ATOM 6829 C C . GLN B 1 471 ? -34.437 60.748 -18.614 1.00 68.46 ? 469 GLN B C 1 ATOM 6830 O O . GLN B 1 471 ? -33.245 60.987 -18.808 1.00 68.90 ? 469 GLN B O 1 ATOM 6831 C CB . GLN B 1 471 ? -35.332 62.538 -17.041 1.00 64.49 ? 469 GLN B CB 1 ATOM 6832 C CG . GLN B 1 471 ? -36.076 63.263 -18.183 1.00 84.80 ? 469 GLN B CG 1 ATOM 6833 C CD . GLN B 1 471 ? -37.539 62.889 -18.304 1.00 109.28 ? 469 GLN B CD 1 ATOM 6834 O OE1 . GLN B 1 471 ? -38.326 63.009 -17.348 1.00 107.38 ? 469 GLN B OE1 1 ATOM 6835 N NE2 . GLN B 1 471 ? -37.943 62.466 -19.503 1.00 97.26 ? 469 GLN B NE2 1 ATOM 6836 N N . LYS B 1 472 ? -35.256 60.278 -19.574 1.00 65.54 ? 470 LYS B N 1 ATOM 6837 C CA . LYS B 1 472 ? -34.806 60.014 -20.947 1.00 65.37 ? 470 LYS B CA 1 ATOM 6838 C C . LYS B 1 472 ? -34.684 61.327 -21.755 1.00 71.32 ? 470 LYS B C 1 ATOM 6839 O O . LYS B 1 472 ? -35.693 61.931 -22.141 1.00 70.96 ? 470 LYS B O 1 ATOM 6840 C CB . LYS B 1 472 ? -35.712 58.988 -21.651 1.00 65.78 ? 470 LYS B CB 1 ATOM 6841 C CG . LYS B 1 472 ? -35.275 58.657 -23.064 1.00 66.92 ? 470 LYS B CG 1 ATOM 6842 C CD . LYS B 1 472 ? -36.145 57.588 -23.674 1.00 74.77 ? 470 LYS B CD 1 ATOM 6843 C CE . LYS B 1 472 ? -35.865 57.428 -25.141 1.00 80.89 ? 470 LYS B CE 1 ATOM 6844 N NZ . LYS B 1 472 ? -36.523 56.212 -25.680 1.00 89.76 ? 470 LYS B NZ 1 ATOM 6845 N N . VAL B 1 473 ? -33.433 61.724 -22.037 1.00 69.36 ? 471 VAL B N 1 ATOM 6846 C CA . VAL B 1 473 ? -33.077 62.938 -22.780 1.00 70.11 ? 471 VAL B CA 1 ATOM 6847 C C . VAL B 1 473 ? -32.956 62.720 -24.307 1.00 76.94 ? 471 VAL B C 1 ATOM 6848 O O . VAL B 1 473 ? -32.989 63.685 -25.068 1.00 76.81 ? 471 VAL B O 1 ATOM 6849 C CB . VAL B 1 473 ? -31.814 63.613 -22.189 1.00 73.69 ? 471 VAL B CB 1 ATOM 6850 C CG1 . VAL B 1 473 ? -32.043 63.975 -20.725 1.00 73.62 ? 471 VAL B CG1 1 ATOM 6851 C CG2 . VAL B 1 473 ? -30.577 62.733 -22.337 1.00 73.20 ? 471 VAL B CG2 1 ATOM 6852 N N . GLY B 1 474 ? -32.816 61.466 -24.729 1.00 75.28 ? 472 GLY B N 1 ATOM 6853 C CA . GLY B 1 474 ? -32.686 61.107 -26.134 1.00 75.23 ? 472 GLY B CA 1 ATOM 6854 C C . GLY B 1 474 ? -32.255 59.675 -26.368 1.00 79.72 ? 472 GLY B C 1 ATOM 6855 O O . GLY B 1 474 ? -32.398 58.816 -25.489 1.00 79.61 ? 472 GLY B O 1 ATOM 6856 N N . TYR B 1 475 ? -31.732 59.420 -27.577 1.00 76.09 ? 473 TYR B N 1 ATOM 6857 C CA . TYR B 1 475 ? -31.300 58.110 -28.040 1.00 76.04 ? 473 TYR B CA 1 ATOM 6858 C C . TYR B 1 475 ? -30.211 58.232 -29.112 1.00 79.55 ? 473 TYR B C 1 ATOM 6859 O O . TYR B 1 475 ? -30.119 59.269 -29.781 1.00 78.11 ? 473 TYR B O 1 ATOM 6860 C CB . TYR B 1 475 ? -32.511 57.327 -28.601 1.00 78.04 ? 473 TYR B CB 1 ATOM 6861 C CG . TYR B 1 475 ? -33.160 57.965 -29.814 1.00 81.48 ? 473 TYR B CG 1 ATOM 6862 C CD1 . TYR B 1 475 ? -34.164 58.922 -29.672 1.00 83.97 ? 473 TYR B CD1 1 ATOM 6863 C CD2 . TYR B 1 475 ? -32.793 57.591 -31.105 1.00 82.54 ? 473 TYR B CD2 1 ATOM 6864 C CE1 . TYR B 1 475 ? -34.768 59.508 -30.785 1.00 85.21 ? 473 TYR B CE1 1 ATOM 6865 C CE2 . TYR B 1 475 ? -33.373 58.188 -32.226 1.00 83.53 ? 473 TYR B CE2 1 ATOM 6866 C CZ . TYR B 1 475 ? -34.367 59.141 -32.061 1.00 91.57 ? 473 TYR B CZ 1 ATOM 6867 O OH . TYR B 1 475 ? -34.951 59.723 -33.162 1.00 92.32 ? 473 TYR B OH 1 ATOM 6868 N N . TRP B 1 476 ? -29.416 57.151 -29.294 1.00 76.54 ? 474 TRP B N 1 ATOM 6869 C CA . TRP B 1 476 ? -28.377 57.046 -30.314 1.00 76.48 ? 474 TRP B CA 1 ATOM 6870 C C . TRP B 1 476 ? -28.627 55.840 -31.193 1.00 78.43 ? 474 TRP B C 1 ATOM 6871 O O . TRP B 1 476 ? -28.378 54.705 -30.780 1.00 78.10 ? 474 TRP B O 1 ATOM 6872 C CB . TRP B 1 476 ? -26.969 56.968 -29.714 1.00 76.26 ? 474 TRP B CB 1 ATOM 6873 C CG . TRP B 1 476 ? -25.902 57.280 -30.727 1.00 78.31 ? 474 TRP B CG 1 ATOM 6874 C CD1 . TRP B 1 476 ? -25.259 58.472 -30.888 1.00 81.54 ? 474 TRP B CD1 1 ATOM 6875 C CD2 . TRP B 1 476 ? -25.411 56.416 -31.767 1.00 78.38 ? 474 TRP B CD2 1 ATOM 6876 N NE1 . TRP B 1 476 ? -24.380 58.399 -31.942 1.00 81.34 ? 474 TRP B NE1 1 ATOM 6877 C CE2 . TRP B 1 476 ? -24.457 57.150 -32.504 1.00 82.62 ? 474 TRP B CE2 1 ATOM 6878 C CE3 . TRP B 1 476 ? -25.673 55.086 -32.139 1.00 79.68 ? 474 TRP B CE3 1 ATOM 6879 C CZ2 . TRP B 1 476 ? -23.764 56.600 -33.588 1.00 81.74 ? 474 TRP B CZ2 1 ATOM 6880 C CZ3 . TRP B 1 476 ? -24.999 54.548 -33.219 1.00 81.17 ? 474 TRP B CZ3 1 ATOM 6881 C CH2 . TRP B 1 476 ? -24.053 55.299 -33.928 1.00 81.79 ? 474 TRP B CH2 1 ATOM 6882 N N . ALA B 1 477 ? -29.070 56.084 -32.422 1.00 74.06 ? 475 ALA B N 1 ATOM 6883 C CA . ALA B 1 477 ? -29.323 55.043 -33.410 1.00 73.92 ? 475 ALA B CA 1 ATOM 6884 C C . ALA B 1 477 ? -28.903 55.614 -34.749 1.00 78.84 ? 475 ALA B C 1 ATOM 6885 O O . ALA B 1 477 ? -29.693 56.268 -35.437 1.00 78.02 ? 475 ALA B O 1 ATOM 6886 C CB . ALA B 1 477 ? -30.798 54.647 -33.409 1.00 74.62 ? 475 ALA B CB 1 ATOM 6887 N N . GLU B 1 478 ? -27.614 55.393 -35.082 1.00 77.03 ? 476 GLU B N 1 ATOM 6888 C CA . GLU B 1 478 ? -26.903 55.897 -36.269 1.00 77.36 ? 476 GLU B CA 1 ATOM 6889 C C . GLU B 1 478 ? -26.918 57.436 -36.295 1.00 79.58 ? 476 GLU B C 1 ATOM 6890 O O . GLU B 1 478 ? -27.360 58.077 -37.250 1.00 78.50 ? 476 GLU B O 1 ATOM 6891 C CB . GLU B 1 478 ? -27.360 55.244 -37.595 1.00 78.97 ? 476 GLU B CB 1 ATOM 6892 C CG . GLU B 1 478 ? -26.455 54.089 -38.020 1.00 94.40 ? 476 GLU B CG 1 ATOM 6893 C CD . GLU B 1 478 ? -24.946 54.227 -37.823 1.00 119.19 ? 476 GLU B CD 1 ATOM 6894 O OE1 . GLU B 1 478 ? -24.349 53.294 -37.238 1.00 126.03 ? 476 GLU B OE1 1 ATOM 6895 O OE2 . GLU B 1 478 ? -24.364 55.263 -38.225 1.00 102.01 ? 476 GLU B OE2 1 ATOM 6896 N N . GLY B 1 479 ? -26.414 57.985 -35.203 1.00 75.63 ? 477 GLY B N 1 ATOM 6897 C CA . GLY B 1 479 ? -26.363 59.408 -34.930 1.00 75.13 ? 477 GLY B CA 1 ATOM 6898 C C . GLY B 1 479 ? -27.009 59.708 -33.594 1.00 78.65 ? 477 GLY B C 1 ATOM 6899 O O . GLY B 1 479 ? -27.832 58.935 -33.083 1.00 78.09 ? 477 GLY B O 1 ATOM 6900 N N . LEU B 1 480 ? -26.625 60.830 -33.020 1.00 74.83 ? 478 LEU B N 1 ATOM 6901 C CA . LEU B 1 480 ? -27.143 61.291 -31.746 1.00 74.79 ? 478 LEU B CA 1 ATOM 6902 C C . LEU B 1 480 ? -28.503 61.980 -31.971 1.00 80.94 ? 478 LEU B C 1 ATOM 6903 O O . LEU B 1 480 ? -28.776 62.437 -33.082 1.00 81.24 ? 478 LEU B O 1 ATOM 6904 C CB . LEU B 1 480 ? -26.097 62.246 -31.147 1.00 74.13 ? 478 LEU B CB 1 ATOM 6905 C CG . LEU B 1 480 ? -26.398 62.954 -29.856 1.00 78.05 ? 478 LEU B CG 1 ATOM 6906 C CD1 . LEU B 1 480 ? -26.619 61.983 -28.746 1.00 78.36 ? 478 LEU B CD1 1 ATOM 6907 C CD2 . LEU B 1 480 ? -25.269 63.843 -29.496 1.00 80.26 ? 478 LEU B CD2 1 ATOM 6908 N N . THR B 1 481 ? -29.380 61.976 -30.950 1.00 77.60 ? 479 THR B N 1 ATOM 6909 C CA . THR B 1 481 ? -30.689 62.639 -30.967 1.00 77.02 ? 479 THR B CA 1 ATOM 6910 C C . THR B 1 481 ? -30.961 63.133 -29.554 1.00 80.65 ? 479 THR B C 1 ATOM 6911 O O . THR B 1 481 ? -31.137 62.337 -28.637 1.00 79.77 ? 479 THR B O 1 ATOM 6912 C CB . THR B 1 481 ? -31.801 61.756 -31.564 1.00 83.52 ? 479 THR B CB 1 ATOM 6913 O OG1 . THR B 1 481 ? -31.349 61.186 -32.793 1.00 87.29 ? 479 THR B OG1 1 ATOM 6914 C CG2 . THR B 1 481 ? -33.096 62.529 -31.806 1.00 77.66 ? 479 THR B CG2 1 ATOM 6915 N N . LEU B 1 482 ? -30.921 64.447 -29.374 1.00 78.14 ? 480 LEU B N 1 ATOM 6916 C CA . LEU B 1 482 ? -31.126 65.066 -28.073 1.00 77.92 ? 480 LEU B CA 1 ATOM 6917 C C . LEU B 1 482 ? -32.213 66.136 -28.059 1.00 83.80 ? 480 LEU B C 1 ATOM 6918 O O . LEU B 1 482 ? -32.499 66.781 -29.075 1.00 83.72 ? 480 LEU B O 1 ATOM 6919 C CB . LEU B 1 482 ? -29.806 65.639 -27.531 1.00 77.34 ? 480 LEU B CB 1 ATOM 6920 C CG . LEU B 1 482 ? -28.929 64.673 -26.754 1.00 81.16 ? 480 LEU B CG 1 ATOM 6921 C CD1 . LEU B 1 482 ? -27.497 65.155 -26.720 1.00 81.35 ? 480 LEU B CD1 1 ATOM 6922 C CD2 . LEU B 1 482 ? -29.422 64.518 -25.340 1.00 82.21 ? 480 LEU B CD2 1 ATOM 6923 N N . ASP B 1 483 ? -32.827 66.288 -26.885 1.00 81.04 ? 481 ASP B N 1 ATOM 6924 C CA . ASP B 1 483 ? -33.823 67.286 -26.543 1.00 80.73 ? 481 ASP B CA 1 ATOM 6925 C C . ASP B 1 483 ? -33.297 67.835 -25.221 1.00 83.79 ? 481 ASP B C 1 ATOM 6926 O O . ASP B 1 483 ? -33.549 67.269 -24.156 1.00 82.03 ? 481 ASP B O 1 ATOM 6927 C CB . ASP B 1 483 ? -35.233 66.673 -26.419 1.00 82.43 ? 481 ASP B CB 1 ATOM 6928 C CG . ASP B 1 483 ? -36.333 67.703 -26.258 1.00 93.72 ? 481 ASP B CG 1 ATOM 6929 O OD1 . ASP B 1 483 ? -36.364 68.675 -27.052 1.00 95.00 ? 481 ASP B OD1 1 ATOM 6930 O OD2 . ASP B 1 483 ? -37.185 67.523 -25.366 1.00 99.41 ? 481 ASP B OD2 1 ATOM 6931 N N . THR B 1 484 ? -32.455 68.878 -25.322 1.00 81.34 ? 482 THR B N 1 ATOM 6932 C CA . THR B 1 484 ? -31.792 69.524 -24.183 1.00 81.41 ? 482 THR B CA 1 ATOM 6933 C C . THR B 1 484 ? -32.799 70.262 -23.267 1.00 84.77 ? 482 THR B C 1 ATOM 6934 O O . THR B 1 484 ? -32.433 70.642 -22.151 1.00 84.46 ? 482 THR B O 1 ATOM 6935 C CB . THR B 1 484 ? -30.609 70.405 -24.651 1.00 88.77 ? 482 THR B CB 1 ATOM 6936 O OG1 . THR B 1 484 ? -31.052 71.309 -25.661 1.00 90.79 ? 482 THR B OG1 1 ATOM 6937 C CG2 . THR B 1 484 ? -29.436 69.585 -25.176 1.00 84.18 ? 482 THR B CG2 1 ATOM 6938 N N . SER B 1 485 ? -34.074 70.411 -23.712 1.00 80.68 ? 483 SER B N 1 ATOM 6939 C CA . SER B 1 485 ? -35.142 71.021 -22.910 1.00 80.21 ? 483 SER B CA 1 ATOM 6940 C C . SER B 1 485 ? -35.327 70.201 -21.623 1.00 84.98 ? 483 SER B C 1 ATOM 6941 O O . SER B 1 485 ? -35.379 70.777 -20.535 1.00 85.75 ? 483 SER B O 1 ATOM 6942 C CB . SER B 1 485 ? -36.443 71.110 -23.708 1.00 83.14 ? 483 SER B CB 1 ATOM 6943 O OG . SER B 1 485 ? -37.241 69.938 -23.656 1.00 92.10 ? 483 SER B OG 1 ATOM 6944 N N . LEU B 1 486 ? -35.313 68.844 -21.759 1.00 80.28 ? 484 LEU B N 1 ATOM 6945 C CA . LEU B 1 486 ? -35.425 67.866 -20.669 1.00 78.91 ? 484 LEU B CA 1 ATOM 6946 C C . LEU B 1 486 ? -34.175 67.851 -19.791 1.00 82.85 ? 484 LEU B C 1 ATOM 6947 O O . LEU B 1 486 ? -34.253 67.378 -18.656 1.00 82.52 ? 484 LEU B O 1 ATOM 6948 C CB . LEU B 1 486 ? -35.716 66.451 -21.210 1.00 78.55 ? 484 LEU B CB 1 ATOM 6949 C CG . LEU B 1 486 ? -36.866 66.309 -22.226 1.00 82.73 ? 484 LEU B CG 1 ATOM 6950 C CD1 . LEU B 1 486 ? -36.750 65.014 -23.003 1.00 82.79 ? 484 LEU B CD1 1 ATOM 6951 C CD2 . LEU B 1 486 ? -38.232 66.410 -21.562 1.00 83.69 ? 484 LEU B CD2 1 ATOM 6952 N N . ILE B 1 487 ? -33.027 68.363 -20.306 1.00 79.89 ? 485 ILE B N 1 ATOM 6953 C CA . ILE B 1 487 ? -31.766 68.439 -19.546 1.00 80.20 ? 485 ILE B CA 1 ATOM 6954 C C . ILE B 1 487 ? -31.784 69.727 -18.695 1.00 86.55 ? 485 ILE B C 1 ATOM 6955 O O . ILE B 1 487 ? -31.924 70.826 -19.264 1.00 87.00 ? 485 ILE B O 1 ATOM 6956 C CB . ILE B 1 487 ? -30.465 68.330 -20.413 1.00 82.53 ? 485 ILE B CB 1 ATOM 6957 C CG1 . ILE B 1 487 ? -30.548 67.162 -21.427 1.00 82.66 ? 485 ILE B CG1 1 ATOM 6958 C CG2 . ILE B 1 487 ? -29.206 68.241 -19.515 1.00 81.85 ? 485 ILE B CG2 1 ATOM 6959 C CD1 . ILE B 1 487 ? -29.374 66.976 -22.433 1.00 83.87 ? 485 ILE B CD1 1 ATOM 6960 N N . PRO B 1 488 ? -31.636 69.610 -17.345 1.00 82.49 ? 486 PRO B N 1 ATOM 6961 C CA . PRO B 1 488 ? -31.670 70.815 -16.493 1.00 82.07 ? 486 PRO B CA 1 ATOM 6962 C C . PRO B 1 488 ? -30.546 71.822 -16.771 1.00 85.35 ? 486 PRO B C 1 ATOM 6963 O O . PRO B 1 488 ? -30.844 72.929 -17.222 1.00 83.98 ? 486 PRO B O 1 ATOM 6964 C CB . PRO B 1 488 ? -31.636 70.253 -15.059 1.00 83.67 ? 486 PRO B CB 1 ATOM 6965 C CG . PRO B 1 488 ? -32.016 68.831 -15.187 1.00 88.31 ? 486 PRO B CG 1 ATOM 6966 C CD . PRO B 1 488 ? -31.497 68.391 -16.527 1.00 83.76 ? 486 PRO B CD 1 ATOM 6967 N N . TRP B 1 489 ? -29.267 71.416 -16.572 1.00 82.40 ? 487 TRP B N 1 ATOM 6968 C CA . TRP B 1 489 ? -28.067 72.249 -16.750 1.00 82.26 ? 487 TRP B CA 1 ATOM 6969 C C . TRP B 1 489 ? -27.796 72.752 -18.191 1.00 84.10 ? 487 TRP B C 1 ATOM 6970 O O . TRP B 1 489 ? -26.826 73.481 -18.393 1.00 82.74 ? 487 TRP B O 1 ATOM 6971 C CB . TRP B 1 489 ? -26.814 71.540 -16.197 1.00 81.43 ? 487 TRP B CB 1 ATOM 6972 C CG . TRP B 1 489 ? -26.584 70.127 -16.666 1.00 82.73 ? 487 TRP B CG 1 ATOM 6973 C CD1 . TRP B 1 489 ? -26.599 69.003 -15.893 1.00 85.65 ? 487 TRP B CD1 1 ATOM 6974 C CD2 . TRP B 1 489 ? -26.175 69.703 -17.983 1.00 82.50 ? 487 TRP B CD2 1 ATOM 6975 N NE1 . TRP B 1 489 ? -26.262 67.904 -16.646 1.00 85.16 ? 487 TRP B NE1 1 ATOM 6976 C CE2 . TRP B 1 489 ? -25.991 68.306 -17.932 1.00 86.70 ? 487 TRP B CE2 1 ATOM 6977 C CE3 . TRP B 1 489 ? -25.933 70.370 -19.198 1.00 83.41 ? 487 TRP B CE3 1 ATOM 6978 C CZ2 . TRP B 1 489 ? -25.605 67.561 -19.056 1.00 85.91 ? 487 TRP B CZ2 1 ATOM 6979 C CZ3 . TRP B 1 489 ? -25.564 69.631 -20.310 1.00 84.73 ? 487 TRP B CZ3 1 ATOM 6980 C CH2 . TRP B 1 489 ? -25.397 68.245 -20.233 1.00 85.44 ? 487 TRP B CH2 1 ATOM 6981 N N . ALA B 1 490 ? -28.631 72.358 -19.175 1.00 80.44 ? 488 ALA B N 1 ATOM 6982 C CA . ALA B 1 490 ? -28.504 72.740 -20.582 1.00 103.66 ? 488 ALA B CA 1 ATOM 6983 C C . ALA B 1 490 ? -28.766 74.228 -20.816 1.00 133.79 ? 488 ALA B C 1 ATOM 6984 O O . ALA B 1 490 ? -28.261 74.796 -21.785 1.00 96.75 ? 488 ALA B O 1 ATOM 6985 C CB . ALA B 1 490 ? -29.450 71.909 -21.426 1.00 104.33 ? 488 ALA B CB 1 HETATM 6986 C C1 . NAG C 2 . ? 22.249 61.009 -17.904 1.00 82.28 ? 601 NAG A C1 1 HETATM 6987 C C2 . NAG C 2 . ? 23.697 60.759 -18.335 1.00 82.61 ? 601 NAG A C2 1 HETATM 6988 C C3 . NAG C 2 . ? 24.621 60.907 -17.125 1.00 85.44 ? 601 NAG A C3 1 HETATM 6989 C C4 . NAG C 2 . ? 24.436 62.280 -16.486 1.00 85.59 ? 601 NAG A C4 1 HETATM 6990 C C5 . NAG C 2 . ? 22.975 62.450 -16.070 1.00 87.22 ? 601 NAG A C5 1 HETATM 6991 C C6 . NAG C 2 . ? 22.654 63.810 -15.480 1.00 90.50 ? 601 NAG A C6 1 HETATM 6992 C C7 . NAG C 2 . ? 24.078 59.323 -20.306 1.00 74.54 ? 601 NAG A C7 1 HETATM 6993 C C8 . NAG C 2 . ? 24.527 57.964 -20.755 1.00 71.32 ? 601 NAG A C8 1 HETATM 6994 N N2 . NAG C 2 . ? 23.903 59.473 -18.981 1.00 78.20 ? 601 NAG A N2 1 HETATM 6995 O O3 . NAG C 2 . ? 25.977 60.715 -17.512 1.00 87.02 ? 601 NAG A O3 1 HETATM 6996 O O4 . NAG C 2 . ? 25.301 62.429 -15.362 1.00 85.48 ? 601 NAG A O4 1 HETATM 6997 O O5 . NAG C 2 . ? 22.113 62.263 -17.210 1.00 85.46 ? 601 NAG A O5 1 HETATM 6998 O O6 . NAG C 2 . ? 23.130 64.905 -16.267 1.00 91.50 ? 601 NAG A O6 1 HETATM 6999 O O7 . NAG C 2 . ? 23.876 60.239 -21.102 1.00 73.21 ? 601 NAG A O7 1 HETATM 7000 C C7 . 52Q D 3 . ? 6.668 33.929 -28.032 1.00 41.81 ? 602 52Q A C7 1 HETATM 7001 C C6 . 52Q D 3 . ? 7.976 33.629 -27.410 1.00 38.68 ? 602 52Q A C6 1 HETATM 7002 C C1 . 52Q D 3 . ? 6.949 34.506 -32.691 1.00 59.57 ? 602 52Q A C1 1 HETATM 7003 C C5 . 52Q D 3 . ? 6.468 35.902 -26.802 1.00 47.82 ? 602 52Q A C5 1 HETATM 7004 C C4 . 52Q D 3 . ? 5.138 34.922 -25.243 1.00 46.80 ? 602 52Q A C4 1 HETATM 7005 C C3 . 52Q D 3 . ? 8.551 32.398 -27.765 1.00 38.58 ? 602 52Q A C3 1 HETATM 7006 C C2 . 52Q D 3 . ? 6.695 35.526 -30.824 1.00 57.71 ? 602 52Q A C2 1 HETATM 7007 C C8 . 52Q D 3 . ? 6.749 33.597 -26.595 1.00 42.23 ? 602 52Q A C8 1 HETATM 7008 C C9 . 52Q D 3 . ? 6.184 35.298 -28.141 1.00 46.35 ? 602 52Q A C9 1 HETATM 7009 C C10 . 52Q D 3 . ? 6.516 34.795 -25.802 1.00 46.02 ? 602 52Q A C10 1 HETATM 7010 N N11 . 52Q D 3 . ? 5.698 34.833 -32.587 1.00 60.32 ? 602 52Q A N11 1 HETATM 7011 N N12 . 52Q D 3 . ? 5.536 35.476 -31.408 1.00 59.95 ? 602 52Q A N12 1 HETATM 7012 N N13 . 52Q D 3 . ? 7.620 34.930 -31.599 1.00 59.98 ? 602 52Q A N13 1 HETATM 7013 N N14 . 52Q D 3 . ? 7.575 35.087 -24.850 1.00 44.26 ? 602 52Q A N14 1 HETATM 7014 O O15 . 52Q D 3 . ? 7.742 31.326 -27.833 1.00 40.93 ? 602 52Q A O15 1 HETATM 7015 O O16 . 52Q D 3 . ? 5.039 35.032 -23.903 1.00 51.26 ? 602 52Q A O16 1 HETATM 7016 O O17 . 52Q D 3 . ? 9.760 32.392 -28.031 1.00 35.98 ? 602 52Q A O17 1 HETATM 7017 O O18 . 52Q D 3 . ? 4.233 34.922 -26.092 1.00 44.02 ? 602 52Q A O18 1 HETATM 7018 S S19 . 52Q D 3 . ? 7.128 36.224 -29.325 1.00 51.08 ? 602 52Q A S19 1 HETATM 7019 C C7 . 52Q E 3 . ? -22.707 43.527 -17.338 1.00 44.39 ? 601 52Q B C7 1 HETATM 7020 C C6 . 52Q E 3 . ? -23.889 44.015 -18.076 1.00 41.34 ? 601 52Q B C6 1 HETATM 7021 C C1 . 52Q E 3 . ? -21.360 44.162 -12.781 1.00 61.00 ? 601 52Q B C1 1 HETATM 7022 C C5 . 52Q E 3 . ? -21.210 44.864 -18.564 1.00 46.16 ? 601 52Q B C5 1 HETATM 7023 C C4 . 52Q E 3 . ? -20.679 43.158 -19.970 1.00 35.77 ? 601 52Q B C4 1 HETATM 7024 C C3 . 52Q E 3 . ? -25.095 43.367 -17.768 1.00 43.54 ? 601 52Q B C3 1 HETATM 7025 C C2 . 52Q E 3 . ? -21.917 45.170 -14.588 1.00 59.85 ? 601 52Q B C2 1 HETATM 7026 C C8 . 52Q E 3 . ? -22.864 43.219 -18.776 1.00 41.32 ? 601 52Q B C8 1 HETATM 7027 C C9 . 52Q E 3 . ? -21.527 44.380 -17.177 1.00 50.43 ? 601 52Q B C9 1 HETATM 7028 C C10 . 52Q E 3 . ? -21.871 43.961 -19.553 1.00 42.58 ? 601 52Q B C10 1 HETATM 7029 N N11 . 52Q E 3 . ? -22.563 44.624 -12.624 1.00 61.64 ? 601 52Q B N11 1 HETATM 7030 N N12 . 52Q E 3 . ? -22.913 45.263 -13.770 1.00 61.80 ? 601 52Q B N12 1 HETATM 7031 N N13 . 52Q E 3 . ? -20.910 44.488 -14.011 1.00 61.50 ? 601 52Q B N13 1 HETATM 7032 N N14 . 52Q E 3 . ? -22.433 44.801 -20.613 1.00 41.64 ? 601 52Q B N14 1 HETATM 7033 O O15 . 52Q E 3 . ? -25.034 42.121 -17.264 1.00 40.51 ? 601 52Q B O15 1 HETATM 7034 O O16 . 52Q E 3 . ? -20.032 42.644 -19.046 1.00 29.48 ? 601 52Q B O16 1 HETATM 7035 O O17 . 52Q E 3 . ? -26.144 44.000 -17.964 1.00 46.94 ? 601 52Q B O17 1 HETATM 7036 O O18 . 52Q E 3 . ? -20.441 43.101 -21.294 1.00 38.60 ? 601 52Q B O18 1 HETATM 7037 S S19 . 52Q E 3 . ? -21.857 45.810 -16.160 1.00 57.28 ? 601 52Q B S19 1 HETATM 7038 O O . HOH F 4 . ? -7.230 33.771 -26.391 1.00 64.77 ? 701 HOH A O 1 HETATM 7039 O O . HOH F 4 . ? 8.132 28.189 -4.478 1.00 44.53 ? 702 HOH A O 1 HETATM 7040 O O . HOH F 4 . ? -0.133 36.134 -26.286 1.00 52.58 ? 703 HOH A O 1 HETATM 7041 O O . HOH F 4 . ? 11.651 5.651 -8.883 1.00 44.72 ? 704 HOH A O 1 HETATM 7042 O O . HOH F 4 . ? 5.277 8.881 -32.711 1.00 62.67 ? 705 HOH A O 1 HETATM 7043 O O . HOH F 4 . ? 13.275 12.423 -31.816 1.00 48.28 ? 706 HOH A O 1 HETATM 7044 O O . HOH F 4 . ? 19.955 13.862 -12.546 1.00 47.16 ? 707 HOH A O 1 HETATM 7045 O O . HOH F 4 . ? 10.777 26.012 -6.448 1.00 54.32 ? 708 HOH A O 1 HETATM 7046 O O . HOH F 4 . ? -9.159 30.179 -15.741 1.00 35.65 ? 709 HOH A O 1 HETATM 7047 O O . HOH F 4 . ? 0.319 9.516 -16.838 1.00 56.75 ? 710 HOH A O 1 HETATM 7048 O O . HOH F 4 . ? 1.734 50.815 -27.309 1.00 31.38 ? 711 HOH A O 1 HETATM 7049 O O . HOH F 4 . ? 0.651 39.626 -27.788 1.00 39.71 ? 712 HOH A O 1 HETATM 7050 O O . HOH F 4 . ? 10.348 37.628 -19.194 1.00 30.12 ? 713 HOH A O 1 HETATM 7051 O O . HOH F 4 . ? -9.110 29.522 -8.011 1.00 46.87 ? 714 HOH A O 1 HETATM 7052 O O . HOH F 4 . ? -1.708 15.035 -12.423 1.00 39.04 ? 715 HOH A O 1 HETATM 7053 O O . HOH F 4 . ? -1.454 10.303 -13.253 1.00 51.37 ? 716 HOH A O 1 HETATM 7054 O O . HOH F 4 . ? 3.758 40.443 -21.468 1.00 35.81 ? 717 HOH A O 1 HETATM 7055 O O . HOH F 4 . ? 19.066 23.074 -40.208 1.00 50.29 ? 718 HOH A O 1 HETATM 7056 O O . HOH F 4 . ? 26.110 50.015 -36.208 1.00 47.47 ? 719 HOH A O 1 HETATM 7057 O O . HOH F 4 . ? -5.545 14.772 -31.803 1.00 57.79 ? 720 HOH A O 1 HETATM 7058 O O . HOH F 4 . ? -13.318 21.503 -12.035 1.00 51.42 ? 721 HOH A O 1 HETATM 7059 O O . HOH F 4 . ? 13.416 60.175 -27.579 1.00 48.35 ? 722 HOH A O 1 HETATM 7060 O O . HOH F 4 . ? 9.649 18.865 -5.016 1.00 48.09 ? 723 HOH A O 1 HETATM 7061 O O . HOH F 4 . ? 20.417 11.042 -32.913 1.00 39.62 ? 724 HOH A O 1 HETATM 7062 O O . HOH F 4 . ? 3.168 40.938 -18.964 1.00 39.31 ? 725 HOH A O 1 HETATM 7063 O O . HOH F 4 . ? 12.450 59.482 -39.155 1.00 43.68 ? 726 HOH A O 1 HETATM 7064 O O . HOH F 4 . ? -2.763 24.545 -16.240 1.00 47.10 ? 727 HOH A O 1 HETATM 7065 O O . HOH F 4 . ? -5.934 30.227 -46.254 1.00 52.74 ? 728 HOH A O 1 HETATM 7066 O O . HOH F 4 . ? 6.058 14.585 -41.604 1.00 52.79 ? 729 HOH A O 1 HETATM 7067 O O . HOH F 4 . ? 14.001 35.533 -28.433 1.00 42.02 ? 730 HOH A O 1 HETATM 7068 O O . HOH F 4 . ? 17.997 34.403 -35.724 1.00 45.05 ? 731 HOH A O 1 HETATM 7069 O O . HOH F 4 . ? 25.161 50.035 -16.810 1.00 71.70 ? 732 HOH A O 1 HETATM 7070 O O . HOH F 4 . ? -8.713 37.261 -12.005 1.00 66.56 ? 733 HOH A O 1 HETATM 7071 O O . HOH F 4 . ? 3.637 59.925 -20.193 1.00 52.45 ? 734 HOH A O 1 HETATM 7072 O O . HOH F 4 . ? 20.091 35.128 -24.586 1.00 65.60 ? 735 HOH A O 1 HETATM 7073 O O . HOH F 4 . ? -9.735 23.079 -10.323 1.00 43.00 ? 736 HOH A O 1 HETATM 7074 O O . HOH F 4 . ? 12.253 6.964 -33.938 1.00 50.03 ? 737 HOH A O 1 HETATM 7075 O O . HOH F 4 . ? 23.673 57.493 -16.982 1.00 64.20 ? 738 HOH A O 1 HETATM 7076 O O . HOH F 4 . ? -1.016 40.900 -38.721 1.00 54.29 ? 739 HOH A O 1 HETATM 7077 O O . HOH F 4 . ? -5.765 37.902 -14.436 1.00 55.82 ? 740 HOH A O 1 HETATM 7078 O O . HOH F 4 . ? 2.509 7.152 1.575 1.00 58.75 ? 741 HOH A O 1 HETATM 7079 O O . HOH F 4 . ? 22.228 11.701 -42.937 1.00 55.40 ? 742 HOH A O 1 HETATM 7080 O O . HOH F 4 . ? -1.094 11.460 -5.405 1.00 40.85 ? 743 HOH A O 1 HETATM 7081 O O . HOH F 4 . ? 17.499 9.982 -36.355 1.00 73.51 ? 744 HOH A O 1 HETATM 7082 O O . HOH F 4 . ? 20.162 30.063 -10.450 1.00 50.24 ? 745 HOH A O 1 HETATM 7083 O O . HOH F 4 . ? 8.053 33.283 -3.512 1.00 43.78 ? 746 HOH A O 1 HETATM 7084 O O . HOH F 4 . ? 2.728 32.080 -37.622 1.00 26.96 ? 747 HOH A O 1 HETATM 7085 O O . HOH F 4 . ? 27.744 38.866 -28.519 1.00 52.00 ? 748 HOH A O 1 HETATM 7086 O O . HOH F 4 . ? 17.859 51.854 -33.611 1.00 49.21 ? 749 HOH A O 1 HETATM 7087 O O . HOH F 4 . ? 2.688 26.392 -28.524 1.00 17.06 ? 750 HOH A O 1 HETATM 7088 O O . HOH F 4 . ? -9.724 28.938 -22.396 1.00 37.48 ? 751 HOH A O 1 HETATM 7089 O O . HOH F 4 . ? 16.479 2.561 -18.809 1.00 40.93 ? 752 HOH A O 1 HETATM 7090 O O . HOH F 4 . ? 18.924 27.763 -25.071 1.00 50.82 ? 753 HOH A O 1 HETATM 7091 O O . HOH F 4 . ? 6.041 2.405 -0.705 1.00 55.64 ? 754 HOH A O 1 HETATM 7092 O O . HOH F 4 . ? 12.197 33.638 -29.297 1.00 49.59 ? 755 HOH A O 1 HETATM 7093 O O . HOH F 4 . ? 14.158 35.261 -25.248 1.00 46.40 ? 756 HOH A O 1 HETATM 7094 O O . HOH F 4 . ? 6.882 65.963 -30.532 1.00 62.99 ? 757 HOH A O 1 HETATM 7095 O O . HOH F 4 . ? -5.222 45.484 -42.128 1.00 48.33 ? 758 HOH A O 1 HETATM 7096 O O . HOH F 4 . ? -8.652 33.704 -18.797 1.00 45.00 ? 759 HOH A O 1 HETATM 7097 O O . HOH F 4 . ? 10.945 28.924 -35.877 1.00 30.91 ? 760 HOH A O 1 HETATM 7098 O O . HOH F 4 . ? -9.527 29.601 -28.136 1.00 43.28 ? 761 HOH A O 1 HETATM 7099 O O . HOH F 4 . ? 3.411 31.440 -31.276 1.00 55.80 ? 762 HOH A O 1 HETATM 7100 O O . HOH F 4 . ? -3.813 26.415 -14.526 1.00 40.03 ? 763 HOH A O 1 HETATM 7101 O O . HOH F 4 . ? 15.061 10.262 -50.301 1.00 48.11 ? 764 HOH A O 1 HETATM 7102 O O . HOH F 4 . ? 0.008 43.871 -47.618 1.00 39.64 ? 765 HOH A O 1 HETATM 7103 O O . HOH F 4 . ? -5.735 15.103 -10.043 1.00 42.57 ? 766 HOH A O 1 HETATM 7104 O O . HOH F 4 . ? -3.983 11.339 -35.886 1.00 55.79 ? 767 HOH A O 1 HETATM 7105 O O . HOH F 4 . ? -5.753 48.297 -45.420 1.00 50.42 ? 768 HOH A O 1 HETATM 7106 O O . HOH F 4 . ? 18.682 53.029 -14.780 1.00 42.96 ? 769 HOH A O 1 HETATM 7107 O O . HOH F 4 . ? -2.067 12.449 -2.789 1.00 39.10 ? 770 HOH A O 1 HETATM 7108 O O . HOH F 4 . ? -1.876 35.270 -7.293 1.00 33.70 ? 771 HOH A O 1 HETATM 7109 O O . HOH F 4 . ? -2.584 37.278 -31.694 1.00 44.69 ? 772 HOH A O 1 HETATM 7110 O O . HOH F 4 . ? 17.610 26.910 -43.128 1.00 49.43 ? 773 HOH A O 1 HETATM 7111 O O . HOH F 4 . ? -4.952 17.506 -2.479 1.00 53.76 ? 774 HOH A O 1 HETATM 7112 O O . HOH F 4 . ? 2.782 8.602 -32.766 1.00 53.00 ? 775 HOH A O 1 HETATM 7113 O O . HOH F 4 . ? 22.833 4.642 -17.562 1.00 53.80 ? 776 HOH A O 1 HETATM 7114 O O . HOH F 4 . ? 23.760 50.982 -14.735 1.00 49.76 ? 777 HOH A O 1 HETATM 7115 O O . HOH F 4 . ? 4.685 35.714 -41.608 1.00 59.58 ? 778 HOH A O 1 HETATM 7116 O O . HOH F 4 . ? 16.523 53.646 -13.069 1.00 41.81 ? 779 HOH A O 1 HETATM 7117 O O . HOH F 4 . ? 18.604 54.067 -37.945 1.00 58.77 ? 780 HOH A O 1 HETATM 7118 O O . HOH F 4 . ? -8.198 41.883 -35.824 1.00 45.78 ? 781 HOH A O 1 HETATM 7119 O O . HOH G 4 . ? -10.272 40.005 -31.401 1.00 56.52 ? 701 HOH B O 1 HETATM 7120 O O . HOH G 4 . ? -44.519 18.134 -27.871 1.00 47.41 ? 702 HOH B O 1 HETATM 7121 O O . HOH G 4 . ? -38.374 23.844 10.678 1.00 55.18 ? 703 HOH B O 1 HETATM 7122 O O . HOH G 4 . ? -29.673 28.257 -3.233 1.00 38.36 ? 704 HOH B O 1 HETATM 7123 O O . HOH G 4 . ? -43.835 25.071 -29.009 1.00 56.56 ? 705 HOH B O 1 HETATM 7124 O O . HOH G 4 . ? -30.795 19.157 -26.358 1.00 45.80 ? 706 HOH B O 1 HETATM 7125 O O . HOH G 4 . ? -45.404 36.460 -4.923 1.00 48.79 ? 707 HOH B O 1 HETATM 7126 O O . HOH G 4 . ? -33.304 41.962 1.351 1.00 48.54 ? 708 HOH B O 1 HETATM 7127 O O . HOH G 4 . ? -36.310 44.807 -20.901 1.00 36.66 ? 709 HOH B O 1 HETATM 7128 O O . HOH G 4 . ? -46.915 31.055 -7.664 1.00 60.44 ? 710 HOH B O 1 HETATM 7129 O O . HOH G 4 . ? -30.259 37.480 -38.857 1.00 44.96 ? 711 HOH B O 1 HETATM 7130 O O . HOH G 4 . ? -10.923 31.911 -28.745 1.00 37.61 ? 712 HOH B O 1 HETATM 7131 O O . HOH G 4 . ? -34.179 45.150 -4.571 1.00 73.65 ? 713 HOH B O 1 HETATM 7132 O O . HOH G 4 . ? -40.444 29.558 -12.806 1.00 52.04 ? 714 HOH B O 1 HETATM 7133 O O . HOH G 4 . ? -34.404 53.843 -13.411 1.00 51.98 ? 715 HOH B O 1 HETATM 7134 O O . HOH G 4 . ? -12.137 29.480 -21.557 1.00 40.57 ? 716 HOH B O 1 HETATM 7135 O O . HOH G 4 . ? -22.990 17.068 -21.720 1.00 49.79 ? 717 HOH B O 1 HETATM 7136 O O . HOH G 4 . ? -5.904 47.940 -21.019 1.00 57.28 ? 718 HOH B O 1 HETATM 7137 O O . HOH G 4 . ? -9.311 33.861 -29.222 1.00 51.91 ? 719 HOH B O 1 HETATM 7138 O O . HOH G 4 . ? -41.450 27.441 5.695 1.00 40.55 ? 720 HOH B O 1 HETATM 7139 O O . HOH G 4 . ? -11.141 31.897 -22.129 1.00 43.67 ? 721 HOH B O 1 HETATM 7140 O O . HOH G 4 . ? -29.648 47.652 -29.031 1.00 54.38 ? 722 HOH B O 1 HETATM 7141 O O . HOH G 4 . ? -33.067 20.785 -10.725 1.00 51.13 ? 723 HOH B O 1 HETATM 7142 O O . HOH G 4 . ? -32.935 28.196 -2.832 1.00 28.13 ? 724 HOH B O 1 HETATM 7143 O O . HOH G 4 . ? -30.767 31.473 2.155 1.00 50.78 ? 725 HOH B O 1 HETATM 7144 O O . HOH G 4 . ? -45.129 34.427 -28.537 1.00 65.47 ? 726 HOH B O 1 HETATM 7145 O O . HOH G 4 . ? -22.678 16.801 -15.741 1.00 78.76 ? 727 HOH B O 1 HETATM 7146 O O . HOH G 4 . ? -16.430 54.288 -38.197 1.00 58.40 ? 728 HOH B O 1 HETATM 7147 O O . HOH G 4 . ? -23.256 35.114 -16.314 1.00 28.04 ? 729 HOH B O 1 HETATM 7148 O O . HOH G 4 . ? -24.887 26.330 -11.322 1.00 37.81 ? 730 HOH B O 1 HETATM 7149 O O . HOH G 4 . ? -39.962 14.721 -42.194 1.00 54.26 ? 731 HOH B O 1 HETATM 7150 O O . HOH G 4 . ? -42.088 23.948 -16.124 1.00 63.24 ? 732 HOH B O 1 HETATM 7151 O O . HOH G 4 . ? -19.815 29.911 -28.338 1.00 27.38 ? 733 HOH B O 1 HETATM 7152 O O . HOH G 4 . ? -46.390 41.862 -22.431 1.00 50.22 ? 734 HOH B O 1 HETATM 7153 O O . HOH G 4 . ? -49.926 33.160 -7.327 1.00 60.30 ? 735 HOH B O 1 HETATM 7154 O O . HOH G 4 . ? -16.665 38.830 -15.760 1.00 49.76 ? 736 HOH B O 1 HETATM 7155 O O . HOH G 4 . ? -12.386 35.668 -19.517 1.00 42.58 ? 737 HOH B O 1 HETATM 7156 O O . HOH G 4 . ? -39.264 18.406 -16.447 1.00 50.20 ? 738 HOH B O 1 HETATM 7157 O O . HOH G 4 . ? -17.900 30.672 -29.984 1.00 33.40 ? 739 HOH B O 1 HETATM 7158 O O . HOH G 4 . ? -29.504 42.049 -6.237 1.00 47.93 ? 740 HOH B O 1 HETATM 7159 O O . HOH G 4 . ? -35.184 22.278 -11.511 1.00 47.52 ? 741 HOH B O 1 HETATM 7160 O O . HOH G 4 . ? -15.591 42.153 -18.433 1.00 39.70 ? 742 HOH B O 1 HETATM 7161 O O . HOH G 4 . ? -35.370 18.214 -46.626 1.00 52.77 ? 743 HOH B O 1 HETATM 7162 O O . HOH G 4 . ? -7.913 40.643 -22.615 1.00 57.28 ? 744 HOH B O 1 HETATM 7163 O O . HOH G 4 . ? -36.885 33.606 -38.426 1.00 24.91 ? 745 HOH B O 1 HETATM 7164 O O . HOH G 4 . ? -45.660 38.643 -28.858 1.00 48.82 ? 746 HOH B O 1 HETATM 7165 O O . HOH G 4 . ? -38.112 54.416 -23.889 1.00 52.93 ? 747 HOH B O 1 HETATM 7166 O O . HOH G 4 . ? -9.883 39.329 -13.366 1.00 45.80 ? 748 HOH B O 1 HETATM 7167 O O . HOH G 4 . ? -8.653 38.210 -35.871 1.00 64.98 ? 749 HOH B O 1 HETATM 7168 O O . HOH G 4 . ? -32.897 50.334 -10.243 1.00 67.46 ? 750 HOH B O 1 HETATM 7169 O O . HOH G 4 . ? -37.354 50.024 -35.072 1.00 65.26 ? 751 HOH B O 1 HETATM 7170 O O . HOH G 4 . ? -44.257 23.907 -7.480 1.00 56.93 ? 752 HOH B O 1 HETATM 7171 O O . HOH G 4 . ? -35.933 26.759 -4.168 1.00 48.49 ? 753 HOH B O 1 HETATM 7172 O O . HOH G 4 . ? -14.865 37.366 -14.319 1.00 38.39 ? 754 HOH B O 1 HETATM 7173 O O . HOH G 4 . ? -19.004 49.358 -0.297 1.00 55.82 ? 755 HOH B O 1 HETATM 7174 O O . HOH G 4 . ? -44.665 21.173 -27.648 1.00 48.96 ? 756 HOH B O 1 HETATM 7175 O O . HOH G 4 . ? -28.805 42.473 -9.448 1.00 31.91 ? 757 HOH B O 1 HETATM 7176 O O . HOH G 4 . ? -25.783 48.963 -35.995 1.00 52.46 ? 758 HOH B O 1 HETATM 7177 O O . HOH G 4 . ? -27.650 23.848 9.186 1.00 58.12 ? 759 HOH B O 1 HETATM 7178 O O . HOH G 4 . ? -42.416 29.971 5.563 1.00 34.91 ? 760 HOH B O 1 HETATM 7179 O O . HOH G 4 . ? -23.115 20.994 -11.719 1.00 53.01 ? 761 HOH B O 1 HETATM 7180 O O . HOH G 4 . ? -30.678 39.882 -40.934 1.00 50.75 ? 762 HOH B O 1 HETATM 7181 O O . HOH G 4 . ? -31.133 43.039 -4.333 1.00 50.35 ? 763 HOH B O 1 HETATM 7182 O O . HOH G 4 . ? -25.009 43.233 -10.144 1.00 66.16 ? 764 HOH B O 1 HETATM 7183 O O . HOH G 4 . ? -36.185 23.355 7.861 1.00 47.14 ? 765 HOH B O 1 HETATM 7184 O O . HOH G 4 . ? -18.974 47.173 -35.696 1.00 48.77 ? 766 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 MET 1 -1 ? ? ? A . n A 1 2 ALA 2 0 ? ? ? A . n A 1 3 LEU 3 1 ? ? ? A . n A 1 4 GLY 4 2 ? ? ? A . n A 1 5 SER 5 3 ? ? ? A . n A 1 6 LEU 6 4 ? ? ? A . n A 1 7 LEU 7 5 ? ? ? A . n A 1 8 ALA 8 6 ? ? ? A . n A 1 9 LEU 9 7 ? ? ? A . n A 1 10 LEU 10 8 ? ? ? A . n A 1 11 ALA 11 9 ? ? ? A . n A 1 12 LEU 12 10 ? ? ? A . n A 1 13 LEU 13 11 ? ? ? A . n A 1 14 LEU 14 12 ? ? ? A . n A 1 15 LEU 15 13 ? ? ? A . n A 1 16 TRP 16 14 ? ? ? A . n A 1 17 GLY 17 15 ? ? ? A . n A 1 18 ALA 18 16 ? ? ? A . n A 1 19 VAL 19 17 ? ? ? A . n A 1 20 ALA 20 18 ? ? ? A . n A 1 21 GLU 21 19 ? ? ? A . n A 1 22 GLY 22 20 ? ? ? A . n A 1 23 PRO 23 21 ? ? ? A . n A 1 24 ALA 24 22 22 ALA ALA A . n A 1 25 LYS 25 23 23 LYS LYS A . n A 1 26 LYS 26 24 24 LYS LYS A . n A 1 27 VAL 27 25 25 VAL VAL A . n A 1 28 LEU 28 26 26 LEU LEU A . n A 1 29 THR 29 27 27 THR THR A . n A 1 30 LEU 30 28 28 LEU LEU A . n A 1 31 GLU 31 29 29 GLU GLU A . n A 1 32 GLY 32 30 30 GLY GLY A . n A 1 33 ASP 33 31 31 ASP ASP A . n A 1 34 LEU 34 32 32 LEU LEU A . n A 1 35 VAL 35 33 33 VAL VAL A . n A 1 36 LEU 36 34 34 LEU LEU A . n A 1 37 GLY 37 35 35 GLY GLY A . n A 1 38 GLY 38 36 36 GLY GLY A . n A 1 39 LEU 39 37 37 LEU LEU A . n A 1 40 PHE 40 38 38 PHE PHE A . n A 1 41 PRO 41 39 39 PRO PRO A . n A 1 42 VAL 42 40 40 VAL VAL A . n A 1 43 HIS 43 41 41 HIS HIS A . n A 1 44 GLN 44 42 42 GLN GLN A . n A 1 45 LYS 45 43 43 LYS LYS A . n A 1 46 GLY 46 44 44 GLY GLY A . n A 1 47 GLY 47 45 45 GLY GLY A . n A 1 48 PRO 48 46 46 PRO PRO A . n A 1 49 ALA 49 47 47 ALA ALA A . n A 1 50 GLU 50 48 48 GLU GLU A . n A 1 51 ASP 51 49 49 ASP ASP A . n A 1 52 CYS 52 50 50 CYS CYS A . n A 1 53 GLY 53 51 51 GLY GLY A . n A 1 54 PRO 54 52 52 PRO PRO A . n A 1 55 VAL 55 53 53 VAL VAL A . n A 1 56 ASN 56 54 54 ASN ASN A . n A 1 57 GLU 57 55 55 GLU GLU A . n A 1 58 HIS 58 56 56 HIS HIS A . n A 1 59 ARG 59 57 57 ARG ARG A . n A 1 60 GLY 60 58 58 GLY GLY A . n A 1 61 ILE 61 59 59 ILE ILE A . n A 1 62 GLN 62 60 60 GLN GLN A . n A 1 63 ARG 63 61 61 ARG ARG A . n A 1 64 LEU 64 62 62 LEU LEU A . n A 1 65 GLU 65 63 63 GLU GLU A . n A 1 66 ALA 66 64 64 ALA ALA A . n A 1 67 MET 67 65 65 MET MET A . n A 1 68 LEU 68 66 66 LEU LEU A . n A 1 69 PHE 69 67 67 PHE PHE A . n A 1 70 ALA 70 68 68 ALA ALA A . n A 1 71 LEU 71 69 69 LEU LEU A . n A 1 72 ASP 72 70 70 ASP ASP A . n A 1 73 ARG 73 71 71 ARG ARG A . n A 1 74 ILE 74 72 72 ILE ILE A . n A 1 75 ASN 75 73 73 ASN ASN A . n A 1 76 ARG 76 74 74 ARG ARG A . n A 1 77 ASP 77 75 75 ASP ASP A . n A 1 78 PRO 78 76 76 PRO PRO A . n A 1 79 HIS 79 77 77 HIS HIS A . n A 1 80 LEU 80 78 78 LEU LEU A . n A 1 81 LEU 81 79 79 LEU LEU A . n A 1 82 PRO 82 80 80 PRO PRO A . n A 1 83 GLY 83 81 81 GLY GLY A . n A 1 84 VAL 84 82 82 VAL VAL A . n A 1 85 ARG 85 83 83 ARG ARG A . n A 1 86 LEU 86 84 84 LEU LEU A . n A 1 87 GLY 87 85 85 GLY GLY A . n A 1 88 ALA 88 86 86 ALA ALA A . n A 1 89 HIS 89 87 87 HIS HIS A . n A 1 90 ILE 90 88 88 ILE ILE A . n A 1 91 LEU 91 89 89 LEU LEU A . n A 1 92 ASP 92 90 90 ASP ASP A . n A 1 93 SER 93 91 91 SER SER A . n A 1 94 CYS 94 92 92 CYS CYS A . n A 1 95 SER 95 93 93 SER SER A . n A 1 96 LYS 96 94 94 LYS LYS A . n A 1 97 ASP 97 95 95 ASP ASP A . n A 1 98 THR 98 96 96 THR THR A . n A 1 99 HIS 99 97 97 HIS HIS A . n A 1 100 ALA 100 98 98 ALA ALA A . n A 1 101 LEU 101 99 99 LEU LEU A . n A 1 102 GLU 102 100 100 GLU GLU A . n A 1 103 GLN 103 101 101 GLN GLN A . n A 1 104 ALA 104 102 102 ALA ALA A . n A 1 105 LEU 105 103 103 LEU LEU A . n A 1 106 ASP 106 104 104 ASP ASP A . n A 1 107 PHE 107 105 105 PHE PHE A . n A 1 108 VAL 108 106 106 VAL VAL A . n A 1 109 ARG 109 107 107 ARG ARG A . n A 1 110 ALA 110 108 108 ALA ALA A . n A 1 111 SER 111 109 109 SER SER A . n A 1 112 LEU 112 110 110 LEU LEU A . n A 1 113 SER 113 111 ? ? ? A . n A 1 114 ARG 114 112 ? ? ? A . n A 1 115 GLY 115 113 ? ? ? A . n A 1 116 ALA 116 114 ? ? ? A . n A 1 117 ASP 117 115 ? ? ? A . n A 1 118 GLY 118 116 ? ? ? A . n A 1 119 SER 119 117 ? ? ? A . n A 1 120 ARG 120 118 ? ? ? A . n A 1 121 HIS 121 119 ? ? ? A . n A 1 122 ILE 122 120 ? ? ? A . n A 1 123 CYS 123 121 ? ? ? A . n A 1 124 PRO 124 122 ? ? ? A . n A 1 125 ASP 125 123 ? ? ? A . n A 1 126 GLY 126 124 ? ? ? A . n A 1 127 SER 127 125 ? ? ? A . n A 1 128 TYR 128 126 ? ? ? A . n A 1 129 ALA 129 127 ? ? ? A . n A 1 130 THR 130 128 ? ? ? A . n A 1 131 HIS 131 129 ? ? ? A . n A 1 132 GLY 132 130 ? ? ? A . n A 1 133 ASP 133 131 ? ? ? A . n A 1 134 ALA 134 132 ? ? ? A . n A 1 135 PRO 135 133 133 PRO PRO A . n A 1 136 THR 136 134 134 THR THR A . n A 1 137 ALA 137 135 135 ALA ALA A . n A 1 138 ILE 138 136 136 ILE ILE A . n A 1 139 THR 139 137 137 THR THR A . n A 1 140 GLY 140 138 138 GLY GLY A . n A 1 141 VAL 141 139 139 VAL VAL A . n A 1 142 ILE 142 140 140 ILE ILE A . n A 1 143 GLY 143 141 141 GLY GLY A . n A 1 144 GLY 144 142 142 GLY GLY A . n A 1 145 SER 145 143 143 SER SER A . n A 1 146 TYR 146 144 144 TYR TYR A . n A 1 147 SER 147 145 145 SER SER A . n A 1 148 ASP 148 146 146 ASP ASP A . n A 1 149 VAL 149 147 147 VAL VAL A . n A 1 150 SER 150 148 148 SER SER A . n A 1 151 ILE 151 149 149 ILE ILE A . n A 1 152 GLN 152 150 150 GLN GLN A . n A 1 153 VAL 153 151 151 VAL VAL A . n A 1 154 ALA 154 152 152 ALA ALA A . n A 1 155 ASN 155 153 153 ASN ASN A . n A 1 156 LEU 156 154 154 LEU LEU A . n A 1 157 LEU 157 155 155 LEU LEU A . n A 1 158 ARG 158 156 156 ARG ARG A . n A 1 159 LEU 159 157 157 LEU LEU A . n A 1 160 PHE 160 158 158 PHE PHE A . n A 1 161 GLN 161 159 159 GLN GLN A . n A 1 162 ILE 162 160 160 ILE ILE A . n A 1 163 PRO 163 161 161 PRO PRO A . n A 1 164 GLN 164 162 162 GLN GLN A . n A 1 165 ILE 165 163 163 ILE ILE A . n A 1 166 SER 166 164 164 SER SER A . n A 1 167 TYR 167 165 165 TYR TYR A . n A 1 168 ALA 168 166 166 ALA ALA A . n A 1 169 SER 169 167 167 SER SER A . n A 1 170 THR 170 168 168 THR THR A . n A 1 171 SER 171 169 169 SER SER A . n A 1 172 ALA 172 170 170 ALA ALA A . n A 1 173 LYS 173 171 171 LYS LYS A . n A 1 174 LEU 174 172 172 LEU LEU A . n A 1 175 SER 175 173 173 SER SER A . n A 1 176 ASP 176 174 174 ASP ASP A . n A 1 177 LYS 177 175 175 LYS LYS A . n A 1 178 SER 178 176 176 SER SER A . n A 1 179 ARG 179 177 177 ARG ARG A . n A 1 180 TYR 180 178 178 TYR TYR A . n A 1 181 ASP 181 179 179 ASP ASP A . n A 1 182 TYR 182 180 180 TYR TYR A . n A 1 183 PHE 183 181 181 PHE PHE A . n A 1 184 ALA 184 182 182 ALA ALA A . n A 1 185 ARG 185 183 183 ARG ARG A . n A 1 186 THR 186 184 184 THR THR A . n A 1 187 VAL 187 185 185 VAL VAL A . n A 1 188 PRO 188 186 186 PRO PRO A . n A 1 189 PRO 189 187 187 PRO PRO A . n A 1 190 ASP 190 188 188 ASP ASP A . n A 1 191 PHE 191 189 189 PHE PHE A . n A 1 192 PHE 192 190 190 PHE PHE A . n A 1 193 GLN 193 191 191 GLN GLN A . n A 1 194 ALA 194 192 192 ALA ALA A . n A 1 195 LYS 195 193 193 LYS LYS A . n A 1 196 ALA 196 194 194 ALA ALA A . n A 1 197 MET 197 195 195 MET MET A . n A 1 198 ALA 198 196 196 ALA ALA A . n A 1 199 GLU 199 197 197 GLU GLU A . n A 1 200 ILE 200 198 198 ILE ILE A . n A 1 201 LEU 201 199 199 LEU LEU A . n A 1 202 ARG 202 200 200 ARG ARG A . n A 1 203 PHE 203 201 201 PHE PHE A . n A 1 204 PHE 204 202 202 PHE PHE A . n A 1 205 ASN 205 203 203 ASN ASN A . n A 1 206 TRP 206 204 204 TRP TRP A . n A 1 207 THR 207 205 205 THR THR A . n A 1 208 TYR 208 206 206 TYR TYR A . n A 1 209 VAL 209 207 207 VAL VAL A . n A 1 210 SER 210 208 208 SER SER A . n A 1 211 THR 211 209 209 THR THR A . n A 1 212 VAL 212 210 210 VAL VAL A . n A 1 213 ALA 213 211 211 ALA ALA A . n A 1 214 SER 214 212 212 SER SER A . n A 1 215 GLU 215 213 213 GLU GLU A . n A 1 216 GLY 216 214 214 GLY GLY A . n A 1 217 ASP 217 215 215 ASP ASP A . n A 1 218 TYR 218 216 216 TYR TYR A . n A 1 219 GLY 219 217 217 GLY GLY A . n A 1 220 GLU 220 218 218 GLU GLU A . n A 1 221 THR 221 219 219 THR THR A . n A 1 222 GLY 222 220 220 GLY GLY A . n A 1 223 ILE 223 221 221 ILE ILE A . n A 1 224 GLU 224 222 222 GLU GLU A . n A 1 225 ALA 225 223 223 ALA ALA A . n A 1 226 PHE 226 224 224 PHE PHE A . n A 1 227 GLU 227 225 225 GLU GLU A . n A 1 228 LEU 228 226 226 LEU LEU A . n A 1 229 GLU 229 227 227 GLU GLU A . n A 1 230 ALA 230 228 228 ALA ALA A . n A 1 231 ARG 231 229 229 ARG ARG A . n A 1 232 ALA 232 230 230 ALA ALA A . n A 1 233 ARG 233 231 231 ARG ARG A . n A 1 234 ASN 234 232 232 ASN ASN A . n A 1 235 ILE 235 233 233 ILE ILE A . n A 1 236 SER 236 234 234 SER SER A . n A 1 237 VAL 237 235 235 VAL VAL A . n A 1 238 ALA 238 236 236 ALA ALA A . n A 1 239 THR 239 237 237 THR THR A . n A 1 240 SER 240 238 238 SER SER A . n A 1 241 GLU 241 239 239 GLU GLU A . n A 1 242 LYS 242 240 240 LYS LYS A . n A 1 243 VAL 243 241 241 VAL VAL A . n A 1 244 GLY 244 242 242 GLY GLY A . n A 1 245 ARG 245 243 243 ARG ARG A . n A 1 246 ALA 246 244 244 ALA ALA A . n A 1 247 MET 247 245 245 MET MET A . n A 1 248 SER 248 246 246 SER SER A . n A 1 249 ARG 249 247 247 ARG ARG A . n A 1 250 ALA 250 248 248 ALA ALA A . n A 1 251 ALA 251 249 249 ALA ALA A . n A 1 252 PHE 252 250 250 PHE PHE A . n A 1 253 GLU 253 251 251 GLU GLU A . n A 1 254 GLY 254 252 252 GLY GLY A . n A 1 255 VAL 255 253 253 VAL VAL A . n A 1 256 VAL 256 254 254 VAL VAL A . n A 1 257 ARG 257 255 255 ARG ARG A . n A 1 258 ALA 258 256 256 ALA ALA A . n A 1 259 LEU 259 257 257 LEU LEU A . n A 1 260 LEU 260 258 258 LEU LEU A . n A 1 261 GLN 261 259 259 GLN GLN A . n A 1 262 LYS 262 260 260 LYS LYS A . n A 1 263 PRO 263 261 261 PRO PRO A . n A 1 264 SER 264 262 262 SER SER A . n A 1 265 ALA 265 263 263 ALA ALA A . n A 1 266 ARG 266 264 264 ARG ARG A . n A 1 267 VAL 267 265 265 VAL VAL A . n A 1 268 ALA 268 266 266 ALA ALA A . n A 1 269 VAL 269 267 267 VAL VAL A . n A 1 270 LEU 270 268 268 LEU LEU A . n A 1 271 PHE 271 269 269 PHE PHE A . n A 1 272 THR 272 270 270 THR THR A . n A 1 273 ARG 273 271 271 ARG ARG A . n A 1 274 SER 274 272 272 SER SER A . n A 1 275 GLU 275 273 273 GLU GLU A . n A 1 276 ASP 276 274 274 ASP ASP A . n A 1 277 ALA 277 275 275 ALA ALA A . n A 1 278 ARG 278 276 276 ARG ARG A . n A 1 279 GLU 279 277 277 GLU GLU A . n A 1 280 LEU 280 278 278 LEU LEU A . n A 1 281 LEU 281 279 279 LEU LEU A . n A 1 282 ALA 282 280 280 ALA ALA A . n A 1 283 ALA 283 281 281 ALA ALA A . n A 1 284 SER 284 282 282 SER SER A . n A 1 285 GLN 285 283 283 GLN GLN A . n A 1 286 ARG 286 284 284 ARG ARG A . n A 1 287 LEU 287 285 285 LEU LEU A . n A 1 288 ASN 288 286 286 ASN ASN A . n A 1 289 ALA 289 287 287 ALA ALA A . n A 1 290 SER 290 288 288 SER SER A . n A 1 291 PHE 291 289 289 PHE PHE A . n A 1 292 THR 292 290 290 THR THR A . n A 1 293 TRP 293 291 291 TRP TRP A . n A 1 294 VAL 294 292 292 VAL VAL A . n A 1 295 ALA 295 293 293 ALA ALA A . n A 1 296 SER 296 294 294 SER SER A . n A 1 297 ASP 297 295 295 ASP ASP A . n A 1 298 GLY 298 296 296 GLY GLY A . n A 1 299 TRP 299 297 297 TRP TRP A . n A 1 300 GLY 300 298 298 GLY GLY A . n A 1 301 ALA 301 299 299 ALA ALA A . n A 1 302 LEU 302 300 300 LEU LEU A . n A 1 303 GLU 303 301 301 GLU GLU A . n A 1 304 SER 304 302 302 SER SER A . n A 1 305 VAL 305 303 303 VAL VAL A . n A 1 306 VAL 306 304 304 VAL VAL A . n A 1 307 ALA 307 305 305 ALA ALA A . n A 1 308 GLY 308 306 306 GLY GLY A . n A 1 309 SER 309 307 307 SER SER A . n A 1 310 GLU 310 308 308 GLU GLU A . n A 1 311 GLY 311 309 309 GLY GLY A . n A 1 312 ALA 312 310 310 ALA ALA A . n A 1 313 ALA 313 311 311 ALA ALA A . n A 1 314 GLU 314 312 312 GLU GLU A . n A 1 315 GLY 315 313 313 GLY GLY A . n A 1 316 ALA 316 314 314 ALA ALA A . n A 1 317 ILE 317 315 315 ILE ILE A . n A 1 318 THR 318 316 316 THR THR A . n A 1 319 ILE 319 317 317 ILE ILE A . n A 1 320 GLU 320 318 318 GLU GLU A . n A 1 321 LEU 321 319 319 LEU LEU A . n A 1 322 ALA 322 320 320 ALA ALA A . n A 1 323 SER 323 321 321 SER SER A . n A 1 324 TYR 324 322 322 TYR TYR A . n A 1 325 PRO 325 323 323 PRO PRO A . n A 1 326 ILE 326 324 324 ILE ILE A . n A 1 327 SER 327 325 325 SER SER A . n A 1 328 ASP 328 326 326 ASP ASP A . n A 1 329 PHE 329 327 327 PHE PHE A . n A 1 330 ALA 330 328 328 ALA ALA A . n A 1 331 SER 331 329 329 SER SER A . n A 1 332 TYR 332 330 330 TYR TYR A . n A 1 333 PHE 333 331 331 PHE PHE A . n A 1 334 GLN 334 332 332 GLN GLN A . n A 1 335 SER 335 333 333 SER SER A . n A 1 336 LEU 336 334 334 LEU LEU A . n A 1 337 ASP 337 335 335 ASP ASP A . n A 1 338 PRO 338 336 336 PRO PRO A . n A 1 339 TRP 339 337 337 TRP TRP A . n A 1 340 ASN 340 338 338 ASN ASN A . n A 1 341 ASN 341 339 339 ASN ASN A . n A 1 342 SER 342 340 340 SER SER A . n A 1 343 ARG 343 341 341 ARG ARG A . n A 1 344 ASN 344 342 342 ASN ASN A . n A 1 345 PRO 345 343 343 PRO PRO A . n A 1 346 TRP 346 344 344 TRP TRP A . n A 1 347 PHE 347 345 345 PHE PHE A . n A 1 348 ARG 348 346 346 ARG ARG A . n A 1 349 GLU 349 347 347 GLU GLU A . n A 1 350 PHE 350 348 348 PHE PHE A . n A 1 351 TRP 351 349 349 TRP TRP A . n A 1 352 GLU 352 350 350 GLU GLU A . n A 1 353 GLN 353 351 351 GLN GLN A . n A 1 354 ARG 354 352 352 ARG ARG A . n A 1 355 PHE 355 353 353 PHE PHE A . n A 1 356 ARG 356 354 354 ARG ARG A . n A 1 357 CYS 357 355 355 CYS CYS A . n A 1 358 SER 358 356 356 SER SER A . n A 1 359 PHE 359 357 357 PHE PHE A . n A 1 360 ARG 360 358 358 ARG ARG A . n A 1 361 GLN 361 359 359 GLN GLN A . n A 1 362 ARG 362 360 360 ARG ARG A . n A 1 363 ASP 363 361 361 ASP ASP A . n A 1 364 CYS 364 362 362 CYS CYS A . n A 1 365 ALA 365 363 363 ALA ALA A . n A 1 366 ALA 366 364 364 ALA ALA A . n A 1 367 HIS 367 365 365 HIS HIS A . n A 1 368 SER 368 366 366 SER SER A . n A 1 369 LEU 369 367 367 LEU LEU A . n A 1 370 ARG 370 368 368 ARG ARG A . n A 1 371 ALA 371 369 369 ALA ALA A . n A 1 372 VAL 372 370 370 VAL VAL A . n A 1 373 PRO 373 371 371 PRO PRO A . n A 1 374 PHE 374 372 372 PHE PHE A . n A 1 375 GLU 375 373 373 GLU GLU A . n A 1 376 GLN 376 374 374 GLN GLN A . n A 1 377 GLU 377 375 375 GLU GLU A . n A 1 378 SER 378 376 376 SER SER A . n A 1 379 LYS 379 377 377 LYS LYS A . n A 1 380 ILE 380 378 378 ILE ILE A . n A 1 381 MET 381 379 379 MET MET A . n A 1 382 PHE 382 380 380 PHE PHE A . n A 1 383 VAL 383 381 381 VAL VAL A . n A 1 384 VAL 384 382 382 VAL VAL A . n A 1 385 ASN 385 383 383 ASN ASN A . n A 1 386 ALA 386 384 384 ALA ALA A . n A 1 387 VAL 387 385 385 VAL VAL A . n A 1 388 TYR 388 386 386 TYR TYR A . n A 1 389 ALA 389 387 387 ALA ALA A . n A 1 390 MET 390 388 388 MET MET A . n A 1 391 ALA 391 389 389 ALA ALA A . n A 1 392 HIS 392 390 390 HIS HIS A . n A 1 393 ALA 393 391 391 ALA ALA A . n A 1 394 LEU 394 392 392 LEU LEU A . n A 1 395 HIS 395 393 393 HIS HIS A . n A 1 396 ASN 396 394 394 ASN ASN A . n A 1 397 MET 397 395 395 MET MET A . n A 1 398 HIS 398 396 396 HIS HIS A . n A 1 399 ARG 399 397 397 ARG ARG A . n A 1 400 ALA 400 398 398 ALA ALA A . n A 1 401 LEU 401 399 399 LEU LEU A . n A 1 402 CYS 402 400 400 CYS CYS A . n A 1 403 PRO 403 401 401 PRO PRO A . n A 1 404 ASN 404 402 402 ASN ASN A . n A 1 405 THR 405 403 403 THR THR A . n A 1 406 THR 406 404 404 THR THR A . n A 1 407 ARG 407 405 405 ARG ARG A . n A 1 408 LEU 408 406 406 LEU LEU A . n A 1 409 CYS 409 407 407 CYS CYS A . n A 1 410 ASP 410 408 408 ASP ASP A . n A 1 411 ALA 411 409 409 ALA ALA A . n A 1 412 MET 412 410 410 MET MET A . n A 1 413 ARG 413 411 411 ARG ARG A . n A 1 414 PRO 414 412 412 PRO PRO A . n A 1 415 VAL 415 413 413 VAL VAL A . n A 1 416 ASN 416 414 414 ASN ASN A . n A 1 417 GLY 417 415 415 GLY GLY A . n A 1 418 ARG 418 416 416 ARG ARG A . n A 1 419 ARG 419 417 417 ARG ARG A . n A 1 420 LEU 420 418 418 LEU LEU A . n A 1 421 TYR 421 419 419 TYR TYR A . n A 1 422 LYS 422 420 420 LYS LYS A . n A 1 423 ASP 423 421 421 ASP ASP A . n A 1 424 PHE 424 422 422 PHE PHE A . n A 1 425 VAL 425 423 423 VAL VAL A . n A 1 426 LEU 426 424 424 LEU LEU A . n A 1 427 ASN 427 425 425 ASN ASN A . n A 1 428 VAL 428 426 426 VAL VAL A . n A 1 429 LYS 429 427 427 LYS LYS A . n A 1 430 PHE 430 428 428 PHE PHE A . n A 1 431 ASP 431 429 429 ASP ASP A . n A 1 432 ALA 432 430 430 ALA ALA A . n A 1 433 PRO 433 431 431 PRO PRO A . n A 1 434 PHE 434 432 432 PHE PHE A . n A 1 435 ARG 435 433 433 ARG ARG A . n A 1 436 PRO 436 434 434 PRO PRO A . n A 1 437 ALA 437 435 435 ALA ALA A . n A 1 438 ASP 438 436 436 ASP ASP A . n A 1 439 THR 439 437 437 THR THR A . n A 1 440 HIS 440 438 438 HIS HIS A . n A 1 441 ASN 441 439 439 ASN ASN A . n A 1 442 GLU 442 440 440 GLU GLU A . n A 1 443 VAL 443 441 441 VAL VAL A . n A 1 444 ARG 444 442 442 ARG ARG A . n A 1 445 PHE 445 443 443 PHE PHE A . n A 1 446 ASP 446 444 444 ASP ASP A . n A 1 447 ARG 447 445 445 ARG ARG A . n A 1 448 PHE 448 446 446 PHE PHE A . n A 1 449 GLY 449 447 447 GLY GLY A . n A 1 450 ASP 450 448 448 ASP ASP A . n A 1 451 GLY 451 449 449 GLY GLY A . n A 1 452 ILE 452 450 450 ILE ILE A . n A 1 453 GLY 453 451 451 GLY GLY A . n A 1 454 ARG 454 452 452 ARG ARG A . n A 1 455 TYR 455 453 453 TYR TYR A . n A 1 456 ASN 456 454 454 ASN ASN A . n A 1 457 ILE 457 455 455 ILE ILE A . n A 1 458 PHE 458 456 456 PHE PHE A . n A 1 459 THR 459 457 457 THR THR A . n A 1 460 TYR 460 458 458 TYR TYR A . n A 1 461 LEU 461 459 459 LEU LEU A . n A 1 462 ARG 462 460 460 ARG ARG A . n A 1 463 ALA 463 461 461 ALA ALA A . n A 1 464 GLY 464 462 462 GLY GLY A . n A 1 465 SER 465 463 463 SER SER A . n A 1 466 GLY 466 464 464 GLY GLY A . n A 1 467 ARG 467 465 465 ARG ARG A . n A 1 468 TYR 468 466 466 TYR TYR A . n A 1 469 ARG 469 467 467 ARG ARG A . n A 1 470 TYR 470 468 468 TYR TYR A . n A 1 471 GLN 471 469 469 GLN GLN A . n A 1 472 LYS 472 470 470 LYS LYS A . n A 1 473 VAL 473 471 471 VAL VAL A . n A 1 474 GLY 474 472 472 GLY GLY A . n A 1 475 TYR 475 473 473 TYR TYR A . n A 1 476 TRP 476 474 474 TRP TRP A . n A 1 477 ALA 477 475 475 ALA ALA A . n A 1 478 GLU 478 476 476 GLU GLU A . n A 1 479 GLY 479 477 477 GLY GLY A . n A 1 480 LEU 480 478 478 LEU LEU A . n A 1 481 THR 481 479 479 THR THR A . n A 1 482 LEU 482 480 480 LEU LEU A . n A 1 483 ASP 483 481 481 ASP ASP A . n A 1 484 THR 484 482 482 THR THR A . n A 1 485 SER 485 483 483 SER SER A . n A 1 486 LEU 486 484 484 LEU LEU A . n A 1 487 ILE 487 485 485 ILE ILE A . n A 1 488 PRO 488 486 486 PRO PRO A . n A 1 489 TRP 489 487 487 TRP TRP A . n A 1 490 ALA 490 488 488 ALA ALA A . n A 1 491 SER 491 489 ? ? ? A . n A 1 492 PRO 492 490 ? ? ? A . n A 1 493 SER 493 491 ? ? ? A . n A 1 494 ALA 494 492 ? ? ? A . n A 1 495 GLY 495 493 ? ? ? A . n A 1 496 GLU 496 494 ? ? ? A . n A 1 497 GLY 497 495 ? ? ? A . n A 1 498 HIS 498 496 ? ? ? A . n A 1 499 HIS 499 497 ? ? ? A . n A 1 500 HIS 500 498 ? ? ? A . n A 1 501 HIS 501 499 ? ? ? A . n A 1 502 HIS 502 500 ? ? ? A . n A 1 503 HIS 503 501 ? ? ? A . n B 1 1 MET 1 -1 ? ? ? B . n B 1 2 ALA 2 0 ? ? ? B . n B 1 3 LEU 3 1 ? ? ? B . n B 1 4 GLY 4 2 ? ? ? B . n B 1 5 SER 5 3 ? ? ? B . n B 1 6 LEU 6 4 ? ? ? B . n B 1 7 LEU 7 5 ? ? ? B . n B 1 8 ALA 8 6 ? ? ? B . n B 1 9 LEU 9 7 ? ? ? B . n B 1 10 LEU 10 8 ? ? ? B . n B 1 11 ALA 11 9 ? ? ? B . n B 1 12 LEU 12 10 ? ? ? B . n B 1 13 LEU 13 11 ? ? ? B . n B 1 14 LEU 14 12 ? ? ? B . n B 1 15 LEU 15 13 ? ? ? B . n B 1 16 TRP 16 14 ? ? ? B . n B 1 17 GLY 17 15 ? ? ? B . n B 1 18 ALA 18 16 ? ? ? B . n B 1 19 VAL 19 17 ? ? ? B . n B 1 20 ALA 20 18 ? ? ? B . n B 1 21 GLU 21 19 ? ? ? B . n B 1 22 GLY 22 20 ? ? ? B . n B 1 23 PRO 23 21 ? ? ? B . n B 1 24 ALA 24 22 ? ? ? B . n B 1 25 LYS 25 23 23 LYS LYS B . n B 1 26 LYS 26 24 24 LYS LYS B . n B 1 27 VAL 27 25 25 VAL VAL B . n B 1 28 LEU 28 26 26 LEU LEU B . n B 1 29 THR 29 27 27 THR THR B . n B 1 30 LEU 30 28 28 LEU LEU B . n B 1 31 GLU 31 29 29 GLU GLU B . n B 1 32 GLY 32 30 30 GLY GLY B . n B 1 33 ASP 33 31 31 ASP ASP B . n B 1 34 LEU 34 32 32 LEU LEU B . n B 1 35 VAL 35 33 33 VAL VAL B . n B 1 36 LEU 36 34 34 LEU LEU B . n B 1 37 GLY 37 35 35 GLY GLY B . n B 1 38 GLY 38 36 36 GLY GLY B . n B 1 39 LEU 39 37 37 LEU LEU B . n B 1 40 PHE 40 38 38 PHE PHE B . n B 1 41 PRO 41 39 39 PRO PRO B . n B 1 42 VAL 42 40 40 VAL VAL B . n B 1 43 HIS 43 41 41 HIS HIS B . n B 1 44 GLN 44 42 42 GLN GLN B . n B 1 45 LYS 45 43 43 LYS LYS B . n B 1 46 GLY 46 44 44 GLY GLY B . n B 1 47 GLY 47 45 45 GLY GLY B . n B 1 48 PRO 48 46 46 PRO PRO B . n B 1 49 ALA 49 47 47 ALA ALA B . n B 1 50 GLU 50 48 48 GLU GLU B . n B 1 51 ASP 51 49 49 ASP ASP B . n B 1 52 CYS 52 50 50 CYS CYS B . n B 1 53 GLY 53 51 51 GLY GLY B . n B 1 54 PRO 54 52 52 PRO PRO B . n B 1 55 VAL 55 53 53 VAL VAL B . n B 1 56 ASN 56 54 54 ASN ASN B . n B 1 57 GLU 57 55 55 GLU GLU B . n B 1 58 HIS 58 56 56 HIS HIS B . n B 1 59 ARG 59 57 57 ARG ARG B . n B 1 60 GLY 60 58 58 GLY GLY B . n B 1 61 ILE 61 59 59 ILE ILE B . n B 1 62 GLN 62 60 60 GLN GLN B . n B 1 63 ARG 63 61 61 ARG ARG B . n B 1 64 LEU 64 62 62 LEU LEU B . n B 1 65 GLU 65 63 63 GLU GLU B . n B 1 66 ALA 66 64 64 ALA ALA B . n B 1 67 MET 67 65 65 MET MET B . n B 1 68 LEU 68 66 66 LEU LEU B . n B 1 69 PHE 69 67 67 PHE PHE B . n B 1 70 ALA 70 68 68 ALA ALA B . n B 1 71 LEU 71 69 69 LEU LEU B . n B 1 72 ASP 72 70 70 ASP ASP B . n B 1 73 ARG 73 71 71 ARG ARG B . n B 1 74 ILE 74 72 72 ILE ILE B . n B 1 75 ASN 75 73 73 ASN ASN B . n B 1 76 ARG 76 74 74 ARG ARG B . n B 1 77 ASP 77 75 75 ASP ASP B . n B 1 78 PRO 78 76 76 PRO PRO B . n B 1 79 HIS 79 77 77 HIS HIS B . n B 1 80 LEU 80 78 78 LEU LEU B . n B 1 81 LEU 81 79 79 LEU LEU B . n B 1 82 PRO 82 80 80 PRO PRO B . n B 1 83 GLY 83 81 81 GLY GLY B . n B 1 84 VAL 84 82 82 VAL VAL B . n B 1 85 ARG 85 83 83 ARG ARG B . n B 1 86 LEU 86 84 84 LEU LEU B . n B 1 87 GLY 87 85 85 GLY GLY B . n B 1 88 ALA 88 86 86 ALA ALA B . n B 1 89 HIS 89 87 87 HIS HIS B . n B 1 90 ILE 90 88 88 ILE ILE B . n B 1 91 LEU 91 89 89 LEU LEU B . n B 1 92 ASP 92 90 90 ASP ASP B . n B 1 93 SER 93 91 91 SER SER B . n B 1 94 CYS 94 92 92 CYS CYS B . n B 1 95 SER 95 93 93 SER SER B . n B 1 96 LYS 96 94 94 LYS LYS B . n B 1 97 ASP 97 95 95 ASP ASP B . n B 1 98 THR 98 96 96 THR THR B . n B 1 99 HIS 99 97 97 HIS HIS B . n B 1 100 ALA 100 98 98 ALA ALA B . n B 1 101 LEU 101 99 99 LEU LEU B . n B 1 102 GLU 102 100 100 GLU GLU B . n B 1 103 GLN 103 101 101 GLN GLN B . n B 1 104 ALA 104 102 102 ALA ALA B . n B 1 105 LEU 105 103 103 LEU LEU B . n B 1 106 ASP 106 104 104 ASP ASP B . n B 1 107 PHE 107 105 105 PHE PHE B . n B 1 108 VAL 108 106 106 VAL VAL B . n B 1 109 ARG 109 107 107 ARG ARG B . n B 1 110 ALA 110 108 108 ALA ALA B . n B 1 111 SER 111 109 109 SER SER B . n B 1 112 LEU 112 110 110 LEU LEU B . n B 1 113 SER 113 111 111 SER SER B . n B 1 114 ARG 114 112 ? ? ? B . n B 1 115 GLY 115 113 ? ? ? B . n B 1 116 ALA 116 114 ? ? ? B . n B 1 117 ASP 117 115 ? ? ? B . n B 1 118 GLY 118 116 ? ? ? B . n B 1 119 SER 119 117 ? ? ? B . n B 1 120 ARG 120 118 ? ? ? B . n B 1 121 HIS 121 119 ? ? ? B . n B 1 122 ILE 122 120 ? ? ? B . n B 1 123 CYS 123 121 ? ? ? B . n B 1 124 PRO 124 122 ? ? ? B . n B 1 125 ASP 125 123 ? ? ? B . n B 1 126 GLY 126 124 ? ? ? B . n B 1 127 SER 127 125 ? ? ? B . n B 1 128 TYR 128 126 ? ? ? B . n B 1 129 ALA 129 127 ? ? ? B . n B 1 130 THR 130 128 ? ? ? B . n B 1 131 HIS 131 129 ? ? ? B . n B 1 132 GLY 132 130 ? ? ? B . n B 1 133 ASP 133 131 ? ? ? B . n B 1 134 ALA 134 132 ? ? ? B . n B 1 135 PRO 135 133 133 PRO PRO B . n B 1 136 THR 136 134 134 THR THR B . n B 1 137 ALA 137 135 135 ALA ALA B . n B 1 138 ILE 138 136 136 ILE ILE B . n B 1 139 THR 139 137 137 THR THR B . n B 1 140 GLY 140 138 138 GLY GLY B . n B 1 141 VAL 141 139 139 VAL VAL B . n B 1 142 ILE 142 140 140 ILE ILE B . n B 1 143 GLY 143 141 141 GLY GLY B . n B 1 144 GLY 144 142 142 GLY GLY B . n B 1 145 SER 145 143 143 SER SER B . n B 1 146 TYR 146 144 144 TYR TYR B . n B 1 147 SER 147 145 145 SER SER B . n B 1 148 ASP 148 146 146 ASP ASP B . n B 1 149 VAL 149 147 147 VAL VAL B . n B 1 150 SER 150 148 148 SER SER B . n B 1 151 ILE 151 149 149 ILE ILE B . n B 1 152 GLN 152 150 150 GLN GLN B . n B 1 153 VAL 153 151 151 VAL VAL B . n B 1 154 ALA 154 152 152 ALA ALA B . n B 1 155 ASN 155 153 153 ASN ASN B . n B 1 156 LEU 156 154 154 LEU LEU B . n B 1 157 LEU 157 155 155 LEU LEU B . n B 1 158 ARG 158 156 156 ARG ARG B . n B 1 159 LEU 159 157 157 LEU LEU B . n B 1 160 PHE 160 158 158 PHE PHE B . n B 1 161 GLN 161 159 159 GLN GLN B . n B 1 162 ILE 162 160 160 ILE ILE B . n B 1 163 PRO 163 161 161 PRO PRO B . n B 1 164 GLN 164 162 162 GLN GLN B . n B 1 165 ILE 165 163 163 ILE ILE B . n B 1 166 SER 166 164 164 SER SER B . n B 1 167 TYR 167 165 165 TYR TYR B . n B 1 168 ALA 168 166 166 ALA ALA B . n B 1 169 SER 169 167 167 SER SER B . n B 1 170 THR 170 168 168 THR THR B . n B 1 171 SER 171 169 169 SER SER B . n B 1 172 ALA 172 170 170 ALA ALA B . n B 1 173 LYS 173 171 171 LYS LYS B . n B 1 174 LEU 174 172 172 LEU LEU B . n B 1 175 SER 175 173 173 SER SER B . n B 1 176 ASP 176 174 174 ASP ASP B . n B 1 177 LYS 177 175 175 LYS LYS B . n B 1 178 SER 178 176 176 SER SER B . n B 1 179 ARG 179 177 177 ARG ARG B . n B 1 180 TYR 180 178 178 TYR TYR B . n B 1 181 ASP 181 179 179 ASP ASP B . n B 1 182 TYR 182 180 180 TYR TYR B . n B 1 183 PHE 183 181 181 PHE PHE B . n B 1 184 ALA 184 182 182 ALA ALA B . n B 1 185 ARG 185 183 183 ARG ARG B . n B 1 186 THR 186 184 184 THR THR B . n B 1 187 VAL 187 185 185 VAL VAL B . n B 1 188 PRO 188 186 186 PRO PRO B . n B 1 189 PRO 189 187 187 PRO PRO B . n B 1 190 ASP 190 188 188 ASP ASP B . n B 1 191 PHE 191 189 189 PHE PHE B . n B 1 192 PHE 192 190 190 PHE PHE B . n B 1 193 GLN 193 191 191 GLN GLN B . n B 1 194 ALA 194 192 192 ALA ALA B . n B 1 195 LYS 195 193 193 LYS LYS B . n B 1 196 ALA 196 194 194 ALA ALA B . n B 1 197 MET 197 195 195 MET MET B . n B 1 198 ALA 198 196 196 ALA ALA B . n B 1 199 GLU 199 197 197 GLU GLU B . n B 1 200 ILE 200 198 198 ILE ILE B . n B 1 201 LEU 201 199 199 LEU LEU B . n B 1 202 ARG 202 200 200 ARG ARG B . n B 1 203 PHE 203 201 201 PHE PHE B . n B 1 204 PHE 204 202 202 PHE PHE B . n B 1 205 ASN 205 203 203 ASN ASN B . n B 1 206 TRP 206 204 204 TRP TRP B . n B 1 207 THR 207 205 205 THR THR B . n B 1 208 TYR 208 206 206 TYR TYR B . n B 1 209 VAL 209 207 207 VAL VAL B . n B 1 210 SER 210 208 208 SER SER B . n B 1 211 THR 211 209 209 THR THR B . n B 1 212 VAL 212 210 210 VAL VAL B . n B 1 213 ALA 213 211 211 ALA ALA B . n B 1 214 SER 214 212 212 SER SER B . n B 1 215 GLU 215 213 213 GLU GLU B . n B 1 216 GLY 216 214 214 GLY GLY B . n B 1 217 ASP 217 215 215 ASP ASP B . n B 1 218 TYR 218 216 216 TYR TYR B . n B 1 219 GLY 219 217 217 GLY GLY B . n B 1 220 GLU 220 218 218 GLU GLU B . n B 1 221 THR 221 219 219 THR THR B . n B 1 222 GLY 222 220 220 GLY GLY B . n B 1 223 ILE 223 221 221 ILE ILE B . n B 1 224 GLU 224 222 222 GLU GLU B . n B 1 225 ALA 225 223 223 ALA ALA B . n B 1 226 PHE 226 224 224 PHE PHE B . n B 1 227 GLU 227 225 225 GLU GLU B . n B 1 228 LEU 228 226 226 LEU LEU B . n B 1 229 GLU 229 227 227 GLU GLU B . n B 1 230 ALA 230 228 228 ALA ALA B . n B 1 231 ARG 231 229 229 ARG ARG B . n B 1 232 ALA 232 230 230 ALA ALA B . n B 1 233 ARG 233 231 231 ARG ARG B . n B 1 234 ASN 234 232 232 ASN ASN B . n B 1 235 ILE 235 233 233 ILE ILE B . n B 1 236 SER 236 234 234 SER SER B . n B 1 237 VAL 237 235 235 VAL VAL B . n B 1 238 ALA 238 236 236 ALA ALA B . n B 1 239 THR 239 237 237 THR THR B . n B 1 240 SER 240 238 238 SER SER B . n B 1 241 GLU 241 239 239 GLU GLU B . n B 1 242 LYS 242 240 240 LYS LYS B . n B 1 243 VAL 243 241 241 VAL VAL B . n B 1 244 GLY 244 242 242 GLY GLY B . n B 1 245 ARG 245 243 243 ARG ARG B . n B 1 246 ALA 246 244 244 ALA ALA B . n B 1 247 MET 247 245 245 MET MET B . n B 1 248 SER 248 246 246 SER SER B . n B 1 249 ARG 249 247 247 ARG ARG B . n B 1 250 ALA 250 248 248 ALA ALA B . n B 1 251 ALA 251 249 249 ALA ALA B . n B 1 252 PHE 252 250 250 PHE PHE B . n B 1 253 GLU 253 251 251 GLU GLU B . n B 1 254 GLY 254 252 252 GLY GLY B . n B 1 255 VAL 255 253 253 VAL VAL B . n B 1 256 VAL 256 254 254 VAL VAL B . n B 1 257 ARG 257 255 255 ARG ARG B . n B 1 258 ALA 258 256 256 ALA ALA B . n B 1 259 LEU 259 257 257 LEU LEU B . n B 1 260 LEU 260 258 258 LEU LEU B . n B 1 261 GLN 261 259 259 GLN GLN B . n B 1 262 LYS 262 260 260 LYS LYS B . n B 1 263 PRO 263 261 261 PRO PRO B . n B 1 264 SER 264 262 262 SER SER B . n B 1 265 ALA 265 263 263 ALA ALA B . n B 1 266 ARG 266 264 264 ARG ARG B . n B 1 267 VAL 267 265 265 VAL VAL B . n B 1 268 ALA 268 266 266 ALA ALA B . n B 1 269 VAL 269 267 267 VAL VAL B . n B 1 270 LEU 270 268 268 LEU LEU B . n B 1 271 PHE 271 269 269 PHE PHE B . n B 1 272 THR 272 270 270 THR THR B . n B 1 273 ARG 273 271 271 ARG ARG B . n B 1 274 SER 274 272 272 SER SER B . n B 1 275 GLU 275 273 273 GLU GLU B . n B 1 276 ASP 276 274 274 ASP ASP B . n B 1 277 ALA 277 275 275 ALA ALA B . n B 1 278 ARG 278 276 276 ARG ARG B . n B 1 279 GLU 279 277 277 GLU GLU B . n B 1 280 LEU 280 278 278 LEU LEU B . n B 1 281 LEU 281 279 279 LEU LEU B . n B 1 282 ALA 282 280 280 ALA ALA B . n B 1 283 ALA 283 281 281 ALA ALA B . n B 1 284 SER 284 282 282 SER SER B . n B 1 285 GLN 285 283 283 GLN GLN B . n B 1 286 ARG 286 284 284 ARG ARG B . n B 1 287 LEU 287 285 285 LEU LEU B . n B 1 288 ASN 288 286 286 ASN ASN B . n B 1 289 ALA 289 287 287 ALA ALA B . n B 1 290 SER 290 288 288 SER SER B . n B 1 291 PHE 291 289 289 PHE PHE B . n B 1 292 THR 292 290 290 THR THR B . n B 1 293 TRP 293 291 291 TRP TRP B . n B 1 294 VAL 294 292 292 VAL VAL B . n B 1 295 ALA 295 293 293 ALA ALA B . n B 1 296 SER 296 294 294 SER SER B . n B 1 297 ASP 297 295 295 ASP ASP B . n B 1 298 GLY 298 296 296 GLY GLY B . n B 1 299 TRP 299 297 297 TRP TRP B . n B 1 300 GLY 300 298 298 GLY GLY B . n B 1 301 ALA 301 299 299 ALA ALA B . n B 1 302 LEU 302 300 300 LEU LEU B . n B 1 303 GLU 303 301 301 GLU GLU B . n B 1 304 SER 304 302 302 SER SER B . n B 1 305 VAL 305 303 303 VAL VAL B . n B 1 306 VAL 306 304 304 VAL VAL B . n B 1 307 ALA 307 305 305 ALA ALA B . n B 1 308 GLY 308 306 306 GLY GLY B . n B 1 309 SER 309 307 307 SER SER B . n B 1 310 GLU 310 308 308 GLU GLU B . n B 1 311 GLY 311 309 309 GLY GLY B . n B 1 312 ALA 312 310 310 ALA ALA B . n B 1 313 ALA 313 311 311 ALA ALA B . n B 1 314 GLU 314 312 312 GLU GLU B . n B 1 315 GLY 315 313 313 GLY GLY B . n B 1 316 ALA 316 314 314 ALA ALA B . n B 1 317 ILE 317 315 315 ILE ILE B . n B 1 318 THR 318 316 316 THR THR B . n B 1 319 ILE 319 317 317 ILE ILE B . n B 1 320 GLU 320 318 318 GLU GLU B . n B 1 321 LEU 321 319 319 LEU LEU B . n B 1 322 ALA 322 320 320 ALA ALA B . n B 1 323 SER 323 321 321 SER SER B . n B 1 324 TYR 324 322 322 TYR TYR B . n B 1 325 PRO 325 323 323 PRO PRO B . n B 1 326 ILE 326 324 324 ILE ILE B . n B 1 327 SER 327 325 325 SER SER B . n B 1 328 ASP 328 326 326 ASP ASP B . n B 1 329 PHE 329 327 327 PHE PHE B . n B 1 330 ALA 330 328 328 ALA ALA B . n B 1 331 SER 331 329 329 SER SER B . n B 1 332 TYR 332 330 330 TYR TYR B . n B 1 333 PHE 333 331 331 PHE PHE B . n B 1 334 GLN 334 332 332 GLN GLN B . n B 1 335 SER 335 333 333 SER SER B . n B 1 336 LEU 336 334 334 LEU LEU B . n B 1 337 ASP 337 335 335 ASP ASP B . n B 1 338 PRO 338 336 336 PRO PRO B . n B 1 339 TRP 339 337 337 TRP TRP B . n B 1 340 ASN 340 338 338 ASN ASN B . n B 1 341 ASN 341 339 339 ASN ASN B . n B 1 342 SER 342 340 340 SER SER B . n B 1 343 ARG 343 341 341 ARG ARG B . n B 1 344 ASN 344 342 342 ASN ASN B . n B 1 345 PRO 345 343 343 PRO PRO B . n B 1 346 TRP 346 344 344 TRP TRP B . n B 1 347 PHE 347 345 345 PHE PHE B . n B 1 348 ARG 348 346 346 ARG ARG B . n B 1 349 GLU 349 347 347 GLU GLU B . n B 1 350 PHE 350 348 348 PHE PHE B . n B 1 351 TRP 351 349 349 TRP TRP B . n B 1 352 GLU 352 350 350 GLU GLU B . n B 1 353 GLN 353 351 351 GLN GLN B . n B 1 354 ARG 354 352 352 ARG ARG B . n B 1 355 PHE 355 353 353 PHE PHE B . n B 1 356 ARG 356 354 354 ARG ARG B . n B 1 357 CYS 357 355 355 CYS CYS B . n B 1 358 SER 358 356 356 SER SER B . n B 1 359 PHE 359 357 357 PHE PHE B . n B 1 360 ARG 360 358 358 ARG ARG B . n B 1 361 GLN 361 359 359 GLN GLN B . n B 1 362 ARG 362 360 360 ARG ARG B . n B 1 363 ASP 363 361 361 ASP ASP B . n B 1 364 CYS 364 362 362 CYS CYS B . n B 1 365 ALA 365 363 363 ALA ALA B . n B 1 366 ALA 366 364 364 ALA ALA B . n B 1 367 HIS 367 365 365 HIS HIS B . n B 1 368 SER 368 366 366 SER SER B . n B 1 369 LEU 369 367 367 LEU LEU B . n B 1 370 ARG 370 368 368 ARG ARG B . n B 1 371 ALA 371 369 369 ALA ALA B . n B 1 372 VAL 372 370 370 VAL VAL B . n B 1 373 PRO 373 371 371 PRO PRO B . n B 1 374 PHE 374 372 372 PHE PHE B . n B 1 375 GLU 375 373 373 GLU GLU B . n B 1 376 GLN 376 374 374 GLN GLN B . n B 1 377 GLU 377 375 375 GLU GLU B . n B 1 378 SER 378 376 376 SER SER B . n B 1 379 LYS 379 377 377 LYS LYS B . n B 1 380 ILE 380 378 378 ILE ILE B . n B 1 381 MET 381 379 379 MET MET B . n B 1 382 PHE 382 380 380 PHE PHE B . n B 1 383 VAL 383 381 381 VAL VAL B . n B 1 384 VAL 384 382 382 VAL VAL B . n B 1 385 ASN 385 383 383 ASN ASN B . n B 1 386 ALA 386 384 384 ALA ALA B . n B 1 387 VAL 387 385 385 VAL VAL B . n B 1 388 TYR 388 386 386 TYR TYR B . n B 1 389 ALA 389 387 387 ALA ALA B . n B 1 390 MET 390 388 388 MET MET B . n B 1 391 ALA 391 389 389 ALA ALA B . n B 1 392 HIS 392 390 390 HIS HIS B . n B 1 393 ALA 393 391 391 ALA ALA B . n B 1 394 LEU 394 392 392 LEU LEU B . n B 1 395 HIS 395 393 393 HIS HIS B . n B 1 396 ASN 396 394 394 ASN ASN B . n B 1 397 MET 397 395 395 MET MET B . n B 1 398 HIS 398 396 396 HIS HIS B . n B 1 399 ARG 399 397 397 ARG ARG B . n B 1 400 ALA 400 398 398 ALA ALA B . n B 1 401 LEU 401 399 399 LEU LEU B . n B 1 402 CYS 402 400 400 CYS CYS B . n B 1 403 PRO 403 401 401 PRO PRO B . n B 1 404 ASN 404 402 402 ASN ASN B . n B 1 405 THR 405 403 403 THR THR B . n B 1 406 THR 406 404 404 THR THR B . n B 1 407 ARG 407 405 405 ARG ARG B . n B 1 408 LEU 408 406 406 LEU LEU B . n B 1 409 CYS 409 407 407 CYS CYS B . n B 1 410 ASP 410 408 408 ASP ASP B . n B 1 411 ALA 411 409 409 ALA ALA B . n B 1 412 MET 412 410 410 MET MET B . n B 1 413 ARG 413 411 411 ARG ARG B . n B 1 414 PRO 414 412 412 PRO PRO B . n B 1 415 VAL 415 413 413 VAL VAL B . n B 1 416 ASN 416 414 414 ASN ASN B . n B 1 417 GLY 417 415 415 GLY GLY B . n B 1 418 ARG 418 416 416 ARG ARG B . n B 1 419 ARG 419 417 417 ARG ARG B . n B 1 420 LEU 420 418 418 LEU LEU B . n B 1 421 TYR 421 419 419 TYR TYR B . n B 1 422 LYS 422 420 420 LYS LYS B . n B 1 423 ASP 423 421 421 ASP ASP B . n B 1 424 PHE 424 422 422 PHE PHE B . n B 1 425 VAL 425 423 423 VAL VAL B . n B 1 426 LEU 426 424 424 LEU LEU B . n B 1 427 ASN 427 425 425 ASN ASN B . n B 1 428 VAL 428 426 426 VAL VAL B . n B 1 429 LYS 429 427 427 LYS LYS B . n B 1 430 PHE 430 428 428 PHE PHE B . n B 1 431 ASP 431 429 429 ASP ASP B . n B 1 432 ALA 432 430 430 ALA ALA B . n B 1 433 PRO 433 431 431 PRO PRO B . n B 1 434 PHE 434 432 432 PHE PHE B . n B 1 435 ARG 435 433 433 ARG ARG B . n B 1 436 PRO 436 434 434 PRO PRO B . n B 1 437 ALA 437 435 435 ALA ALA B . n B 1 438 ASP 438 436 436 ASP ASP B . n B 1 439 THR 439 437 437 THR THR B . n B 1 440 HIS 440 438 438 HIS HIS B . n B 1 441 ASN 441 439 439 ASN ASN B . n B 1 442 GLU 442 440 440 GLU GLU B . n B 1 443 VAL 443 441 441 VAL VAL B . n B 1 444 ARG 444 442 442 ARG ARG B . n B 1 445 PHE 445 443 443 PHE PHE B . n B 1 446 ASP 446 444 444 ASP ASP B . n B 1 447 ARG 447 445 445 ARG ARG B . n B 1 448 PHE 448 446 446 PHE PHE B . n B 1 449 GLY 449 447 447 GLY GLY B . n B 1 450 ASP 450 448 448 ASP ASP B . n B 1 451 GLY 451 449 449 GLY GLY B . n B 1 452 ILE 452 450 450 ILE ILE B . n B 1 453 GLY 453 451 451 GLY GLY B . n B 1 454 ARG 454 452 452 ARG ARG B . n B 1 455 TYR 455 453 453 TYR TYR B . n B 1 456 ASN 456 454 454 ASN ASN B . n B 1 457 ILE 457 455 455 ILE ILE B . n B 1 458 PHE 458 456 456 PHE PHE B . n B 1 459 THR 459 457 457 THR THR B . n B 1 460 TYR 460 458 458 TYR TYR B . n B 1 461 LEU 461 459 459 LEU LEU B . n B 1 462 ARG 462 460 460 ARG ARG B . n B 1 463 ALA 463 461 461 ALA ALA B . n B 1 464 GLY 464 462 462 GLY GLY B . n B 1 465 SER 465 463 463 SER SER B . n B 1 466 GLY 466 464 464 GLY GLY B . n B 1 467 ARG 467 465 465 ARG ARG B . n B 1 468 TYR 468 466 466 TYR TYR B . n B 1 469 ARG 469 467 467 ARG ARG B . n B 1 470 TYR 470 468 468 TYR TYR B . n B 1 471 GLN 471 469 469 GLN GLN B . n B 1 472 LYS 472 470 470 LYS LYS B . n B 1 473 VAL 473 471 471 VAL VAL B . n B 1 474 GLY 474 472 472 GLY GLY B . n B 1 475 TYR 475 473 473 TYR TYR B . n B 1 476 TRP 476 474 474 TRP TRP B . n B 1 477 ALA 477 475 475 ALA ALA B . n B 1 478 GLU 478 476 476 GLU GLU B . n B 1 479 GLY 479 477 477 GLY GLY B . n B 1 480 LEU 480 478 478 LEU LEU B . n B 1 481 THR 481 479 479 THR THR B . n B 1 482 LEU 482 480 480 LEU LEU B . n B 1 483 ASP 483 481 481 ASP ASP B . n B 1 484 THR 484 482 482 THR THR B . n B 1 485 SER 485 483 483 SER SER B . n B 1 486 LEU 486 484 484 LEU LEU B . n B 1 487 ILE 487 485 485 ILE ILE B . n B 1 488 PRO 488 486 486 PRO PRO B . n B 1 489 TRP 489 487 487 TRP TRP B . n B 1 490 ALA 490 488 488 ALA ALA B . n B 1 491 SER 491 489 ? ? ? B . n B 1 492 PRO 492 490 ? ? ? B . n B 1 493 SER 493 491 ? ? ? B . n B 1 494 ALA 494 492 ? ? ? B . n B 1 495 GLY 495 493 ? ? ? B . n B 1 496 GLU 496 494 ? ? ? B . n B 1 497 GLY 497 495 ? ? ? B . n B 1 498 HIS 498 496 ? ? ? B . n B 1 499 HIS 499 497 ? ? ? B . n B 1 500 HIS 500 498 ? ? ? B . n B 1 501 HIS 501 499 ? ? ? B . n B 1 502 HIS 502 500 ? ? ? B . n B 1 503 HIS 503 501 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 601 500 NAG NAG A . D 3 52Q 1 602 1 52Q SX1 A . E 3 52Q 1 601 2 52Q SX1 B . F 4 HOH 1 701 99 HOH HOH A . F 4 HOH 2 702 18 HOH HOH A . F 4 HOH 3 703 165 HOH HOH A . F 4 HOH 4 704 185 HOH HOH A . F 4 HOH 5 705 195 HOH HOH A . F 4 HOH 6 706 183 HOH HOH A . F 4 HOH 7 707 109 HOH HOH A . F 4 HOH 8 708 179 HOH HOH A . F 4 HOH 9 709 104 HOH HOH A . F 4 HOH 10 710 91 HOH HOH A . F 4 HOH 11 711 24 HOH HOH A . F 4 HOH 12 712 166 HOH HOH A . F 4 HOH 13 713 98 HOH HOH A . F 4 HOH 14 714 8 HOH HOH A . F 4 HOH 15 715 105 HOH HOH A . F 4 HOH 16 716 225 HOH HOH A . F 4 HOH 17 717 9 HOH HOH A . F 4 HOH 18 718 15 HOH HOH A . F 4 HOH 19 719 126 HOH HOH A . F 4 HOH 20 720 88 HOH HOH A . F 4 HOH 21 721 150 HOH HOH A . F 4 HOH 22 722 146 HOH HOH A . F 4 HOH 23 723 108 HOH HOH A . F 4 HOH 24 724 44 HOH HOH A . F 4 HOH 25 725 173 HOH HOH A . F 4 HOH 26 726 103 HOH HOH A . F 4 HOH 27 727 194 HOH HOH A . F 4 HOH 28 728 209 HOH HOH A . F 4 HOH 29 729 191 HOH HOH A . F 4 HOH 30 730 170 HOH HOH A . F 4 HOH 31 731 50 HOH HOH A . F 4 HOH 32 732 181 HOH HOH A . F 4 HOH 33 733 226 HOH HOH A . F 4 HOH 34 734 101 HOH HOH A . F 4 HOH 35 735 172 HOH HOH A . F 4 HOH 36 736 62 HOH HOH A . F 4 HOH 37 737 162 HOH HOH A . F 4 HOH 38 738 241 HOH HOH A . F 4 HOH 39 739 143 HOH HOH A . F 4 HOH 40 740 48 HOH HOH A . F 4 HOH 41 741 107 HOH HOH A . F 4 HOH 42 742 75 HOH HOH A . F 4 HOH 43 743 106 HOH HOH A . F 4 HOH 44 744 184 HOH HOH A . F 4 HOH 45 745 66 HOH HOH A . F 4 HOH 46 746 112 HOH HOH A . F 4 HOH 47 747 1 HOH HOH A . F 4 HOH 48 748 110 HOH HOH A . F 4 HOH 49 749 3 HOH HOH A . F 4 HOH 50 750 2 HOH HOH A . F 4 HOH 51 751 164 HOH HOH A . F 4 HOH 52 752 36 HOH HOH A . F 4 HOH 53 753 228 HOH HOH A . F 4 HOH 54 754 229 HOH HOH A . F 4 HOH 55 755 140 HOH HOH A . F 4 HOH 56 756 12 HOH HOH A . F 4 HOH 57 757 69 HOH HOH A . F 4 HOH 58 758 217 HOH HOH A . F 4 HOH 59 759 32 HOH HOH A . F 4 HOH 60 760 74 HOH HOH A . F 4 HOH 61 761 153 HOH HOH A . F 4 HOH 62 762 67 HOH HOH A . F 4 HOH 63 763 97 HOH HOH A . F 4 HOH 64 764 159 HOH HOH A . F 4 HOH 65 765 31 HOH HOH A . F 4 HOH 66 766 81 HOH HOH A . F 4 HOH 67 767 60 HOH HOH A . F 4 HOH 68 768 130 HOH HOH A . F 4 HOH 69 769 29 HOH HOH A . F 4 HOH 70 770 51 HOH HOH A . F 4 HOH 71 771 47 HOH HOH A . F 4 HOH 72 772 94 HOH HOH A . F 4 HOH 73 773 208 HOH HOH A . F 4 HOH 74 774 16 HOH HOH A . F 4 HOH 75 775 39 HOH HOH A . F 4 HOH 76 776 204 HOH HOH A . F 4 HOH 77 777 182 HOH HOH A . F 4 HOH 78 778 21 HOH HOH A . F 4 HOH 79 779 180 HOH HOH A . F 4 HOH 80 780 221 HOH HOH A . F 4 HOH 81 781 218 HOH HOH A . G 4 HOH 1 701 169 HOH HOH B . G 4 HOH 2 702 42 HOH HOH B . G 4 HOH 3 703 238 HOH HOH B . G 4 HOH 4 704 203 HOH HOH B . G 4 HOH 5 705 174 HOH HOH B . G 4 HOH 6 706 77 HOH HOH B . G 4 HOH 7 707 68 HOH HOH B . G 4 HOH 8 708 215 HOH HOH B . G 4 HOH 9 709 128 HOH HOH B . G 4 HOH 10 710 236 HOH HOH B . G 4 HOH 11 711 79 HOH HOH B . G 4 HOH 12 712 198 HOH HOH B . G 4 HOH 13 713 214 HOH HOH B . G 4 HOH 14 714 176 HOH HOH B . G 4 HOH 15 715 155 HOH HOH B . G 4 HOH 16 716 197 HOH HOH B . G 4 HOH 17 717 152 HOH HOH B . G 4 HOH 18 718 117 HOH HOH B . G 4 HOH 19 719 167 HOH HOH B . G 4 HOH 20 720 239 HOH HOH B . G 4 HOH 21 721 125 HOH HOH B . G 4 HOH 22 722 190 HOH HOH B . G 4 HOH 23 723 113 HOH HOH B . G 4 HOH 24 724 11 HOH HOH B . G 4 HOH 25 725 122 HOH HOH B . G 4 HOH 26 726 200 HOH HOH B . G 4 HOH 27 727 193 HOH HOH B . G 4 HOH 28 728 46 HOH HOH B . G 4 HOH 29 729 5 HOH HOH B . G 4 HOH 30 730 129 HOH HOH B . G 4 HOH 31 731 196 HOH HOH B . G 4 HOH 32 732 121 HOH HOH B . G 4 HOH 33 733 10 HOH HOH B . G 4 HOH 34 734 142 HOH HOH B . G 4 HOH 35 735 70 HOH HOH B . G 4 HOH 36 736 188 HOH HOH B . G 4 HOH 37 737 87 HOH HOH B . G 4 HOH 38 738 73 HOH HOH B . G 4 HOH 39 739 233 HOH HOH B . G 4 HOH 40 740 95 HOH HOH B . G 4 HOH 41 741 205 HOH HOH B . G 4 HOH 42 742 7 HOH HOH B . G 4 HOH 43 743 124 HOH HOH B . G 4 HOH 44 744 134 HOH HOH B . G 4 HOH 45 745 34 HOH HOH B . G 4 HOH 46 746 28 HOH HOH B . G 4 HOH 47 747 120 HOH HOH B . G 4 HOH 48 748 145 HOH HOH B . G 4 HOH 49 749 199 HOH HOH B . G 4 HOH 50 750 213 HOH HOH B . G 4 HOH 51 751 163 HOH HOH B . G 4 HOH 52 752 237 HOH HOH B . G 4 HOH 53 753 86 HOH HOH B . G 4 HOH 54 754 53 HOH HOH B . G 4 HOH 55 755 63 HOH HOH B . G 4 HOH 56 756 148 HOH HOH B . G 4 HOH 57 757 55 HOH HOH B . G 4 HOH 58 758 131 HOH HOH B . G 4 HOH 59 759 240 HOH HOH B . G 4 HOH 60 760 4 HOH HOH B . G 4 HOH 61 761 33 HOH HOH B . G 4 HOH 62 762 22 HOH HOH B . G 4 HOH 63 763 17 HOH HOH B . G 4 HOH 64 764 212 HOH HOH B . G 4 HOH 65 765 160 HOH HOH B . G 4 HOH 66 766 141 HOH HOH B . # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2015-09-09 2 'Structure model' 1 1 2015-10-07 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Database references' # loop_ _software.citation_id _software.classification _software.compiler_name _software.compiler_version _software.contact_author _software.contact_author_email _software.date _software.description _software.dependencies _software.hardware _software.language _software.location _software.mods _software.name _software.os _software.os_version _software.type _software.version _software.pdbx_ordinal ? refinement ? ? ? ? ? ? ? ? ? ? ? BUSTER ? ? ? 2.11.5 1 ? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? MOSFLM ? ? ? . 2 ? 'data scaling' ? ? ? ? ? ? ? ? ? ? ? SCALA ? ? ? . 3 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ALA A 102 ? ? -55.79 -9.16 2 1 ALA A 166 ? ? -142.14 -11.51 3 1 SER A 325 ? ? -42.48 -77.71 4 1 ASN A 339 ? ? -103.46 50.56 5 1 ARG A 360 ? ? 33.39 37.90 6 1 ALA A 364 ? ? -48.67 -4.14 7 1 CYS A 400 ? ? -116.74 67.16 8 1 ALA A 435 ? ? -36.63 -35.17 9 1 SER A 463 ? ? -66.25 10.39 10 1 LEU B 110 ? ? -64.42 0.69 11 1 SER B 143 ? ? -97.02 -68.93 12 1 ALA B 166 ? ? -147.49 -24.49 13 1 TYR B 178 ? ? -118.93 63.15 14 1 ALA B 211 ? ? -177.15 144.51 15 1 ASN B 286 ? ? 37.92 71.64 16 1 ALA B 305 ? ? -34.56 111.04 17 1 ARG B 354 ? ? 30.51 48.29 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ARG 264 ? CG ? A ARG 266 CG 2 1 Y 1 A ARG 264 ? CD ? A ARG 266 CD 3 1 Y 1 A ARG 264 ? NE ? A ARG 266 NE 4 1 Y 1 A ARG 264 ? CZ ? A ARG 266 CZ 5 1 Y 1 A ARG 264 ? NH1 ? A ARG 266 NH1 6 1 Y 1 A ARG 264 ? NH2 ? A ARG 266 NH2 7 1 Y 1 A ASP 436 ? CG ? A ASP 438 CG 8 1 Y 1 A ASP 436 ? OD1 ? A ASP 438 OD1 9 1 Y 1 A ASP 436 ? OD2 ? A ASP 438 OD2 10 1 Y 1 A HIS 438 ? CG ? A HIS 440 CG 11 1 Y 1 A HIS 438 ? ND1 ? A HIS 440 ND1 12 1 Y 1 A HIS 438 ? CD2 ? A HIS 440 CD2 13 1 Y 1 A HIS 438 ? CE1 ? A HIS 440 CE1 14 1 Y 1 A HIS 438 ? NE2 ? A HIS 440 NE2 15 1 Y 1 B ARG 200 ? CG ? B ARG 202 CG 16 1 Y 1 B ARG 200 ? CD ? B ARG 202 CD 17 1 Y 1 B ARG 200 ? NE ? B ARG 202 NE 18 1 Y 1 B ARG 200 ? CZ ? B ARG 202 CZ 19 1 Y 1 B ARG 200 ? NH1 ? B ARG 202 NH1 20 1 Y 1 B ARG 200 ? NH2 ? B ARG 202 NH2 21 1 Y 1 B ARG 247 ? CG ? B ARG 249 CG 22 1 Y 1 B ARG 247 ? CD ? B ARG 249 CD 23 1 Y 1 B ARG 247 ? NE ? B ARG 249 NE 24 1 Y 1 B ARG 247 ? CZ ? B ARG 249 CZ 25 1 Y 1 B ARG 247 ? NH1 ? B ARG 249 NH1 26 1 Y 1 B ARG 247 ? NH2 ? B ARG 249 NH2 27 1 Y 1 B SER 262 ? OG ? B SER 264 OG 28 1 Y 1 B ARG 264 ? CG ? B ARG 266 CG 29 1 Y 1 B ARG 264 ? CD ? B ARG 266 CD 30 1 Y 1 B ARG 264 ? NE ? B ARG 266 NE 31 1 Y 1 B ARG 264 ? CZ ? B ARG 266 CZ 32 1 Y 1 B ARG 264 ? NH1 ? B ARG 266 NH1 33 1 Y 1 B ARG 264 ? NH2 ? B ARG 266 NH2 34 1 Y 1 B ASP 436 ? CG ? B ASP 438 CG 35 1 Y 1 B ASP 436 ? OD1 ? B ASP 438 OD1 36 1 Y 1 B ASP 436 ? OD2 ? B ASP 438 OD2 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A MET -1 ? A MET 1 2 1 Y 1 A ALA 0 ? A ALA 2 3 1 Y 1 A LEU 1 ? A LEU 3 4 1 Y 1 A GLY 2 ? A GLY 4 5 1 Y 1 A SER 3 ? A SER 5 6 1 Y 1 A LEU 4 ? A LEU 6 7 1 Y 1 A LEU 5 ? A LEU 7 8 1 Y 1 A ALA 6 ? A ALA 8 9 1 Y 1 A LEU 7 ? A LEU 9 10 1 Y 1 A LEU 8 ? A LEU 10 11 1 Y 1 A ALA 9 ? A ALA 11 12 1 Y 1 A LEU 10 ? A LEU 12 13 1 Y 1 A LEU 11 ? A LEU 13 14 1 Y 1 A LEU 12 ? A LEU 14 15 1 Y 1 A LEU 13 ? A LEU 15 16 1 Y 1 A TRP 14 ? A TRP 16 17 1 Y 1 A GLY 15 ? A GLY 17 18 1 Y 1 A ALA 16 ? A ALA 18 19 1 Y 1 A VAL 17 ? A VAL 19 20 1 Y 1 A ALA 18 ? A ALA 20 21 1 Y 1 A GLU 19 ? A GLU 21 22 1 Y 1 A GLY 20 ? A GLY 22 23 1 Y 1 A PRO 21 ? A PRO 23 24 1 Y 1 A SER 111 ? A SER 113 25 1 Y 1 A ARG 112 ? A ARG 114 26 1 Y 1 A GLY 113 ? A GLY 115 27 1 Y 1 A ALA 114 ? A ALA 116 28 1 Y 1 A ASP 115 ? A ASP 117 29 1 Y 1 A GLY 116 ? A GLY 118 30 1 Y 1 A SER 117 ? A SER 119 31 1 Y 1 A ARG 118 ? A ARG 120 32 1 Y 1 A HIS 119 ? A HIS 121 33 1 Y 1 A ILE 120 ? A ILE 122 34 1 Y 1 A CYS 121 ? A CYS 123 35 1 Y 1 A PRO 122 ? A PRO 124 36 1 Y 1 A ASP 123 ? A ASP 125 37 1 Y 1 A GLY 124 ? A GLY 126 38 1 Y 1 A SER 125 ? A SER 127 39 1 Y 1 A TYR 126 ? A TYR 128 40 1 Y 1 A ALA 127 ? A ALA 129 41 1 Y 1 A THR 128 ? A THR 130 42 1 Y 1 A HIS 129 ? A HIS 131 43 1 Y 1 A GLY 130 ? A GLY 132 44 1 Y 1 A ASP 131 ? A ASP 133 45 1 Y 1 A ALA 132 ? A ALA 134 46 1 Y 1 A SER 489 ? A SER 491 47 1 Y 1 A PRO 490 ? A PRO 492 48 1 Y 1 A SER 491 ? A SER 493 49 1 Y 1 A ALA 492 ? A ALA 494 50 1 Y 1 A GLY 493 ? A GLY 495 51 1 Y 1 A GLU 494 ? A GLU 496 52 1 Y 1 A GLY 495 ? A GLY 497 53 1 Y 1 A HIS 496 ? A HIS 498 54 1 Y 1 A HIS 497 ? A HIS 499 55 1 Y 1 A HIS 498 ? A HIS 500 56 1 Y 1 A HIS 499 ? A HIS 501 57 1 Y 1 A HIS 500 ? A HIS 502 58 1 Y 1 A HIS 501 ? A HIS 503 59 1 Y 1 B MET -1 ? B MET 1 60 1 Y 1 B ALA 0 ? B ALA 2 61 1 Y 1 B LEU 1 ? B LEU 3 62 1 Y 1 B GLY 2 ? B GLY 4 63 1 Y 1 B SER 3 ? B SER 5 64 1 Y 1 B LEU 4 ? B LEU 6 65 1 Y 1 B LEU 5 ? B LEU 7 66 1 Y 1 B ALA 6 ? B ALA 8 67 1 Y 1 B LEU 7 ? B LEU 9 68 1 Y 1 B LEU 8 ? B LEU 10 69 1 Y 1 B ALA 9 ? B ALA 11 70 1 Y 1 B LEU 10 ? B LEU 12 71 1 Y 1 B LEU 11 ? B LEU 13 72 1 Y 1 B LEU 12 ? B LEU 14 73 1 Y 1 B LEU 13 ? B LEU 15 74 1 Y 1 B TRP 14 ? B TRP 16 75 1 Y 1 B GLY 15 ? B GLY 17 76 1 Y 1 B ALA 16 ? B ALA 18 77 1 Y 1 B VAL 17 ? B VAL 19 78 1 Y 1 B ALA 18 ? B ALA 20 79 1 Y 1 B GLU 19 ? B GLU 21 80 1 Y 1 B GLY 20 ? B GLY 22 81 1 Y 1 B PRO 21 ? B PRO 23 82 1 Y 1 B ALA 22 ? B ALA 24 83 1 Y 1 B ARG 112 ? B ARG 114 84 1 Y 1 B GLY 113 ? B GLY 115 85 1 Y 1 B ALA 114 ? B ALA 116 86 1 Y 1 B ASP 115 ? B ASP 117 87 1 Y 1 B GLY 116 ? B GLY 118 88 1 Y 1 B SER 117 ? B SER 119 89 1 Y 1 B ARG 118 ? B ARG 120 90 1 Y 1 B HIS 119 ? B HIS 121 91 1 Y 1 B ILE 120 ? B ILE 122 92 1 Y 1 B CYS 121 ? B CYS 123 93 1 Y 1 B PRO 122 ? B PRO 124 94 1 Y 1 B ASP 123 ? B ASP 125 95 1 Y 1 B GLY 124 ? B GLY 126 96 1 Y 1 B SER 125 ? B SER 127 97 1 Y 1 B TYR 126 ? B TYR 128 98 1 Y 1 B ALA 127 ? B ALA 129 99 1 Y 1 B THR 128 ? B THR 130 100 1 Y 1 B HIS 129 ? B HIS 131 101 1 Y 1 B GLY 130 ? B GLY 132 102 1 Y 1 B ASP 131 ? B ASP 133 103 1 Y 1 B ALA 132 ? B ALA 134 104 1 Y 1 B SER 489 ? B SER 491 105 1 Y 1 B PRO 490 ? B PRO 492 106 1 Y 1 B SER 491 ? B SER 493 107 1 Y 1 B ALA 492 ? B ALA 494 108 1 Y 1 B GLY 493 ? B GLY 495 109 1 Y 1 B GLU 494 ? B GLU 496 110 1 Y 1 B GLY 495 ? B GLY 497 111 1 Y 1 B HIS 496 ? B HIS 498 112 1 Y 1 B HIS 497 ? B HIS 499 113 1 Y 1 B HIS 498 ? B HIS 500 114 1 Y 1 B HIS 499 ? B HIS 501 115 1 Y 1 B HIS 500 ? B HIS 502 116 1 Y 1 B HIS 501 ? B HIS 503 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 '(1R,2S,4R,5R,6R)-2-amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid' 52Q 4 water HOH #